LOCUS       DAFAZV010000001       171673 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFAZV010000001 DAFAZV010000000
VERSION     DAFAZV010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 171673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 171673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..171673
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.001"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            137..1801
                     /locus_tag="KOU88_000001"
     CDS             137..1801
                     /locus_tag="KOU88_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBK3209930.1"
                     /translation="MNNENEQLKSDLLINDEKIKNLNFKIPWYYSLWTISILILSTFS
                     TYSISFIVAIIFLFKRNKIMKKHKDSISILLSDVEKINNKYILLNDEIKMKEKHFEDL
                     CESNENKLKELSNLLDKKKVEIDKFDSENQDKFKLIEELKIEKERLDNLIKDKNILKD
                     NINTLNSHLEELKNEREELRDINTTLKNKKEELKRLSEELIQTEDEVLLQSFGLYNPK
                     YDFENSDEYMEKLKEIREMQKLLIRNKTGVKYSDSWTVDGSVQKGRTMTNQNIKTALK
                     LFNSECDIAMSKVSFKNIDSIEKRIRKAFTDTNKLNTSNKVSIKENYLNLKIDELYLY
                     YEYLQMKEEEKEEQRALREQMKEEALVQKEIENQKRKLKKEELQFKNELLRLKSTIPE
                     DENDKLEWEQKINSIEEKLALLSKDLDDVLNREQNTRAGHVYIISNIGSFGENIYKIG
                     VTRRLDPTERINELSSASVPFKYDIHATIFSEDAPKLESALHKAFDNKRVNKVNNRKE
                     FFEVTLDEIRSEVEKNFDKTVEYTKLAEAQEYRQTLKIQELNNKLA"
     gene            2256..2657
                     /locus_tag="KOU88_000002"
     CDS             2256..2657
                     /locus_tag="KOU88_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBK3209931.1"
                     /translation="MKKDIYVYPAILSYDENGISVEFPDLPGCYTCGDTTEEALKMAK
                     EALGLHLYGMEEDNDIIPNSTTIDKLNLEKNQIPTLIEIYMPIHRKAIENYSVKKTLT
                     IPQWLNREAEKHKVNFSQILQEALKNHLNIH"
     gene            2722..3840
                     /locus_tag="KOU88_000003"
     CDS             2722..3840
                     /locus_tag="KOU88_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK3209932.1"
                     /translation="MNIKSAFIRKRGGKFYVYVEYIEETTGKIKQKSYGSYEKKKDAE
                     KHLIEIKSTINNNKFITPSKTTLVERCYKYIMSNEKKWSPYTTVNRKSWVKNYIEPFF
                     KDTILIDVNPSLLQIFIDKNFDGSAPSTAKVRYNFLSSVLKEAYRLKEISENPCDFVK
                     LPAQNVTYEIEIYNREETLLLIEKLKDSLIEIPILLMLLLGLRIGEVAGLRWSDVDLD
                     NSIININQILIYANSKITFKEPKTAKSKRTLSVPKELIEKLKIEKLKQNKIKLQGTLE
                     NENNLVCLNTNLKPWIPTALSKTFHNFIKRNNLRNIRVHDLRHTNASLLLLGGTNMKV
                     VSERLGHTDIKITMNRYSHVLEEMDKEASDNLSKLLFK"
     gene            complement(3991..4671)
                     /locus_tag="KOU88_000004"
     CDS             complement(3991..4671)
                     /locus_tag="KOU88_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3209933.1"
                     /translation="MQTKILIIDGDKDNCQKLKGFLEEKGISIDLAYNCEEAIGKIFS
                     NKYDLIFLEIILSDGDGWTLCKKIRNVTTCPIVYMTYINEDQSILNALNSGGDDYLIK
                     PLNLEILYAKVKAILRRMNSYVNNNENNTKLEEYNRTSGVIKLEDKIIKLTPTENKLL
                     NFFIENPEKTLTTKEIYEHVWMNEYLEDNYSVVVAVNGLRKKIEKDYKNPQKIITIRG
                     AGYYFNKE"
     gene            complement(4721..6736)
                     /locus_tag="KOU88_000005"
     CDS             complement(4721..6736)
                     /locus_tag="KOU88_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBK3209934.1"
                     /translation="MKKYNILKGTLIVLIVSLLAITGLNLLYKYDNKYTYKSIRASNG
                     ILTIDNDTFTKGKLVFLIDDWEFYNHKIFKPNDFTEQDIKPEYVFIGQYPDFSMRKGT
                     QSPYGNATYRMRIKNEGKDKLLSLELPEIFSASEVWINGEMVSKLGDVGTEKYRPKIK
                     NSVVSFIAKKNTEIIINVSNFSHYYSGLYYPPALGETKDISNMMFYRLLFYSIICFTT
                     FAIAIFSLSVWFLSNKSKIYLYFGCMCVFFAIHVSYPFVHLLGLPLVSFTYAVEDLSY
                     FMVVLCIICINGSISKIEENKVYRFLILPLGITMSIISIVIPIILFPYDMYFVNIYGK
                     LIDIYKYIVFIYILMSSLVSIYKKTCSEHISSYILVSVNTVFGISILFDAVTSNRFEP
                     IFTGWQTEYCGFVIVILFSVMMINRNRIIIKENEKLTRNLEHEVEVRTNELTTLLNER
                     KRFLADVAHDLKAPVSAIQAFIDLIKVGNIHVDEETRTYLYAINQKSNEVQNRVRSLQ
                     EFTSQDKSIGISEKICLNNFIKEIYENNLPDTQACGVNFEAYVLEKKIYAKINKEMLT
                     RAFENLIYNALTFTPFDGKIILSMDKEDGFAIIKISDNGKGIPPENIPKVFDRFFTER
                     DNNEPKGQGLGLYIVKSIIREHGGEIFVDSELGKGTVFTIKLSLCFL"
     gene            complement(6808..7485)
                     /locus_tag="KOU88_000006"
     CDS             complement(6808..7485)
                     /locus_tag="KOU88_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3209935.1"
                     /translation="MYNLLVVDDDVDILNINQIYFSNIGFNVYTSETAKDAMDIVESI
                     VLDCIILDISLPDIDGYKMCNDIKEKVNIPIIFLSNYEHEEEKVRGFLAGGDDYITKP
                     YSLKELELRIYARMRQYKNITSVPNVLKFSALVINVNSRKVTFDGESIDLTTMEFEIL
                     LFLAENKEQVFSKIEIYNQVWKMPDIGDQHTVQVHIAQMRKKINSLSREHQYIQTVWG
                     KGYKFVP"
     regulatory      complement(8065..8148)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            complement(8381..9214)
                     /locus_tag="KOU88_000007"
     CDS             complement(8381..9214)
                     /locus_tag="KOU88_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3209936.1"
                     /translation="MFKKKIGVLLASTMLVGALAVGCGSNSGDSGDSSKVSVSGSTSI
                     GPLMETIGEKFQEKNQGVSVEVQQIGSSGGIKNAIEGTSEIGMSSRDLKDEEKSAGLK
                     ETKIAIDGIALITNTANSVKNLTMDQVKGIYTGKITNWKEVGGNDAPIVIVSREEGSG
                     TRDGFQEIVGFDSEELTKDAQISDGSGNIKTTVEGNENAIGYISFGYVDEKVNSLKIN
                     DVEATDANVIANKYPISRPFILVNKEDGLSEKGKALIDYILSDEGQALVSEKGFIKVN
                     Q"
     gene            complement(9466..11250)
                     /gene="pepF"
                     /locus_tag="KOU88_000008"
     CDS             complement(9466..11250)
                     /gene="pepF"
                     /locus_tag="KOU88_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBK3209937.1"
                     /translation="MGTDRSTIEEKYKWKIDKMYSSKEEIEKDISKVKNLIQEVKEYK
                     GKLSESKENLYKVLNISENASRIVQNLYVYTHMKQHEDTRINDNQGRATKTEMLSTDL
                     GVATSYIVPEILAIEENKLSEYLKDEKLSFYAKYIKDILRDKPHTLSEREEEILAATS
                     ELSTIPENVYDMLAYADMEFPEIEDEEGNKVKLSHSNYSLFIKSKNSRVRKDAFEGEF
                     STYEKYKNTFASTLYGGIKSEIFYAKTRKYNSAIEASLFSDDVSLDVYNNLISAIDKS
                     IPNLNKYVELKKKFLGLNEIHMYDLYVPLTDKFDMDIPYDKAQDIILEALKPLGEEYL
                     KIIKSAFDEGWIDVYDNEGKKGGAYSWGSYDSHPYILMSYKNDLNSLFTLIHELGHSV
                     HSHYSRTSQPFLYSDYKIFVAEVASTLNELLLINYLLENSKSKDETIYLLNYYLEQFR
                     TTVHRQTMFAEFEKIVHQRVESGEPLTADEFTNIYYKLNEKYYGKSAIVDKQIGIEWA
                     RIPHFYSNFYVYKYATGFSAASALSQQILSEGSTAVDRYINFLKSGGSEYPLEQLKSA
                     GVDMTKKESIEEALNVFAELVNKLEKEL"
     gene            complement(11316..11981)
                     /locus_tag="KOU88_000009"
     CDS             complement(11316..11981)
                     /locus_tag="KOU88_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBK3209938.1"
                     /translation="MIDIGSKEIAIRLLLALIIGGIIGLEREKIRQFAGFRTHILIAI
                     GSCIVSITSIQLFFDYNLYTNADPARMPAQVLSGIGFLGAGAILKNKGGVKGLTTAAG
                     MWATACIGIAVGYGYYELAILGGLFVMIALFVLRIINTFLFSQEKNVLILKLSNLDSI
                     PFLYDKFEKNQLIVRNMEIECRNEEYWKVNFFVSYAKRIHLHDVMKEINMIEGVINVD
                     YLD"
     gene            complement(12132..12293)
                     /locus_tag="KOU88_000010"
     CDS             complement(12132..12293)
                     /locus_tag="KOU88_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-phosphate phosphatase Spo0E family
                     protein"
                     /protein_id="HBK3209939.1"
                     /translation="MANNELEALKNEIEAVREEINTYIEYPEIFQEELVESSKKIDIL
                     INKYMYLSK"
     gene            complement(12371..12880)
                     /locus_tag="KOU88_000011"
     CDS             complement(12371..12880)
                     /locus_tag="KOU88_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBK3209940.1"
                     /translation="MKTRKMTFLGLMIGYSLALYVLETYIPNPLIVIFPGAKLGLSNI
                     ITLISLMLLGVKDTVIIVTIRVILSSIFAGPLSYLLFSIGGAYLSLLFMYLASKIKDL
                     SLIGISIIGAIGHNIGQLIVASLIIENILAIGYLPFMLMASLVTGMFVGLVSRYTIPK
                     LKHFYSKFY"
     gene            13086..13304
                     /locus_tag="KOU88_000012"
     CDS             13086..13304
                     /locus_tag="KOU88_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBK3209941.1"
                     /translation="MTVYDLKIGEKGFINSIDGDIKLSKRLLALGCINSTEIEVKKVA
                     PLGDPIIIRFRGFDLAIRKSDAKNISLQ"
     gene            13322..15268
                     /gene="feoB"
                     /locus_tag="KOU88_000013"
     CDS             13322..15268
                     /gene="feoB"
                     /locus_tag="KOU88_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBK3209942.1"
                     /translation="MINVALLGNPNVGKTTVFNLLTGSNQYVGNWPGVTIEKKEGFLG
                     KEIKVVDLPGIYAMDTFSNEEKVSKSYLENEDVDVIVNVVDASNLSRNLYLTTQLMQF
                     NKPIVILLNMLDIAESKGVNIDAKKLSEELGVIVVPIIAKKKNGVDRIEEEIKGATQK
                     AFIYQKNFGSETETYKKLESILSRCTKTTYTQKKSISDKIDNIVLNPILAYPIFIGVL
                     FLLFKFTFDWVGGPLQEGFASLIEAYISAPVSDMLSNSSPWFKSLIVDGIIGGVGGTL
                     PFFPLIFTLFFGISLFEDSGYMSRTAFLMDKVMRKVGLSGKAFIPIVMGMGCSSPAIM
                     ATRTLESEKDRRVTALIAPLMTCGAKLPIYALFVAIFFPHNAALVTTSLYLVGIVMAI
                     VVALFLNKTAFKTEAEPFILELPEYRIPTIDALIKNTWNKSKGFLIRVVTVMFAMSVV
                     IWGLSSFNVFGYTEDINVSFLATLGHIISPIFKPLGFDDWRTSVAILSGLGAKEIVVN
                     SLNILYGNLTVVLPTIFNGVTAYTFLIFTALYTPCIAALATMKKEYGNKMMFTSFAYQ
                     FILAWIMAFIVKSIGGVLFMGNSIIEALIGGIIIVLALFILFNKFKSTKNGNVCSGCS
                     ICSGCPSANSCSSKEDSNKKNNAH"
     gene            complement(15447..16502)
                     /locus_tag="KOU88_000014"
     CDS             complement(15447..16502)
                     /locus_tag="KOU88_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK3209943.1"
                     /translation="MTIQDYMLETAVRMREIISNADSLFNEVKRTNLKKIIITGSGTS
                     YHSGVQVQPYLQNLLDIDVVKMYPFMITEDTFKFDNENTLVVGVSQGGSSYSTYNAMK
                     LAEDKGCKIASMAGCKNALIDEISDYILTVNCGEEKSGAKTKGYYCTKLNLMLLGLQI
                     AREKGIISSEKYNEEINKILDAINRFEAVYKLSKQWIERNKEKLVNSKEIRIIGHSDI
                     YGDTLEAALKLLETMRIPVTGYEFEEFIHGIYNAINSDSTIFILDTGKEPRVTKMIDV
                     LSGWTENVFAIGRDVTENDKNLKIDITDNPYYQTFNFIVPIQLICGEIPTLRGVDPSV
                     PKDTRFHMKLGSKKLNK"
     gene            complement(16550..17350)
                     /locus_tag="KOU88_000015"
     CDS             complement(16550..17350)
                     /locus_tag="KOU88_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK3209944.1"
                     /translation="MNKLTKKELRSMFWRSFALQGAFNYERMQNLGYCYSMLPAIKKL
                     YNKKENQAKAIERHLEIFNTTTVVVPAILGITAAMEEENANNPEFDESSISAVKTALM
                     GPLAGIGDSLFWGTFRIIAAGVGVSLAKEGNIFGPLLFLLLYNIPAFALRIFGLKYGY
                     QVGVNSLERIQREGLMEKIMSMATTVGLFVVGGMVATMLSITTPLKFNLNGAEVILQD
                     ILDKIIPNMLPLTFAFVIYYMLKRKVSVTKLTIGTIVTGIALHAIGLL"
     gene            complement(17343..18134)
                     /locus_tag="KOU88_000016"
     CDS             complement(17343..18134)
                     /locus_tag="KOU88_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3209945.1"
                     /translation="MLVQATMLAIIAGVGILDGRIFGQSMLDRPIVTGMLVGLVLGDI
                     KSGIMIGAQLELIWMGIAGIGAATPPDVVTGGVLGTAFAILSGNGAEVALAVAVPVAV
                     LAQSLGVLVRIINSYFSQKAVFYAKQADFKKVTIMMWLPVILFFLSTSVPTFLAIMIG
                     ADKVTALINAIPKVILDGLGVAGTLLPAVGFALLMDMLLSKKMSVFFFIGFLLASYGG
                     LDITAIALFGVCVAFVLNFYINNKENNQNPQLAINTLTEGEIDFE"
     gene            complement(18174..18596)
                     /locus_tag="KOU88_000017"
     CDS             complement(18174..18596)
                     /locus_tag="KOU88_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBK3209946.1"
                     /translation="MKKFLIATHGELSRELVDTSKLIIGSLTNIEYFCMTTDKSADDA
                     EKEIRSILSNNKDSEEFVVLTDVFGGSVANICTNLLLQGFKFELLTGVNLPMLLSILL
                     LVEEDTKLIVKSGLEEAKNGIVYVNELLENQNKIKNVM"
     gene            complement(18612..19091)
                     /locus_tag="KOU88_000018"
     CDS             complement(18612..19091)
                     /locus_tag="KOU88_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3209947.1"
                     /translation="MVSLMRIDDRLIHGQVAYGWATSLGINVILVANDEAKNDQMKAM
                     SLNLAKPSNVTLYIRGVEESGEIVEKFASSKKSNVLVLVKNTKDALVVAKNSGGVLKE
                     INVGGLRYEEGKKKLTDLVAVDDDDINNFKQIGDLGIDIEFRMLPRDKKKQLSDLIK"
     gene            complement(19223..21979)
                     /locus_tag="KOU88_000019"
     CDS             complement(19223..21979)
                     /locus_tag="KOU88_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3209948.1"
                     /translation="MRDEILSFVNECVLFNNFDELKKESGIITEDIVKKFNLSRTQSS
                     RLLNDLVKSDNLIKINSRPVIFLPKNKINDVVGPTKKSIYENLDELKNECKLLKQETV
                     FNSIIGYDNSLKEVIEQIKTAVLYPNGGLTIMLTGESGVGKTFLAKIIYKYSVSSNVL
                     EKNSPYNVLNCAQYYNNLELLSSLLFGHVKGAYTGANESRAGLIEQSDGGVLFLDEVH
                     RLNSEGQEKLFTFMDTGTFSRIGENGVIRKARVRLIFATTESLSEFLQTFLRRIPINI
                     YVPNIEERGTIEKRKIVEHFIYEESKVLGLPIEITQITLNAILKIKFKGNIGECKNVI
                     KYACGRAYAKNQRRNGNIFVTLQDLPRNLYIENVDIFQFQSGKSKSIIFSPKQFSIEM
                     SNGRNKRNIIYQSFIKCLDYFDRLEKNEITKEKFSKKSSNLMIRLMDNLVFSNNDENN
                     NVLMELIISIMQDIFRNLEVNNNIKYDGNNVLAFSSYLYLKDESYQLSDEYKALENKL
                     LIYLKKESYKEYSIIIKISTLITNRLDMYLNNVDIIIMIIFIKSTIIRMKFNQVNATI
                     IAHGYATASSMANVCNRMLGKNIFTAIDMPIDATIADVSKQMSRYLEGDRIKNGLIVL
                     FDMGSLNLIYEDLKNKINSPMLFIDQISTISALEVGNLLMQGKNIEEIAEIMDEETKP
                     NIQLYYPQKNKEYAIISSCFTGIGTAIKIQHLLSESLIGIVDVKIIPYDYDSLVSMGD
                     KEPVFEMYDVMAIVGTANPNVNGVDFILLEDIISGKGEDDVFRIFSRVVENEKIKNIN
                     DSIVKNFSLIRVIDSLTILDSKKIIERIEEGINAIENIQKKKLSNDKKISLYVHLSCM
                     IERLVRQTEIEEYTDMDLLIKNHHSEVKLIKNAFSVLEKSYSVQIPISEIGYIYNIIY
                     GLPQ"
     gene            complement(22577..23380)
                     /gene="proC"
                     /locus_tag="KOU88_000020"
     CDS             complement(22577..23380)
                     /gene="proC"
                     /locus_tag="KOU88_000020"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBK3209949.1"
                     /translation="MKTLGFIGSGNMGSAMIGGIVQSGLVKAEDITVSDLSQVALDKV
                     KEKFGVNTTTDSKVAVTNSDVVIVALKPNICEKALTPLKELIDANKIIVSIAAGKTIE
                     SLESFIGSDKKIVRVMPNTPALVGEGMSALCKNSNVTDEELNMIKALFESFGEAEIVS
                     EYLMDTVTGISGSSPAYVFMFIEAMADAAVLAGMPRQQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPAGTTIEAVKVLEEEGFRAAVIKSIVACIDKSKDMSK"
     gene            complement(23705..26074)
                     /locus_tag="KOU88_000021"
     CDS             complement(23705..26074)
                     /locus_tag="KOU88_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBK3209950.1"
                     /translation="MARGTFERTKKLREESINAEPHISIERAVLMTEAYKKYEGSVEI
                     PVLRALSFKHYIENRTLSINDGELIVGEKGDSPNGAPTYPEICCHTMEDLEVMHNRDI
                     INFSVSEEARKIHKEEIIPFWKKRQTRDKIINAMTPEWLAAYEAGMFTEFMEQRAPGH
                     TVCGDTIYKKGFLDLKKDIEARLKELDFLNDLDAYNKKADLEAMAIACDAMVILGKRY
                     AEKARQMAEEETDEAKKKDLLLIAETCDVVPAHKPETYHQAIQMYWFVHIGVTTELNI
                     WDAFTPGRLDQHLNPFYERDVENGILDRDRAQELLECLWVKFNNQPAPPKVGITLKES
                     STYTDFANINTGGINPDGQDGVNEVSYIILDVMDEMKLIQPSSNVQISKKTPQKFLKR
                     ACEISRKGWGQPAFYNTEAIVQELMEAGKTIEDARLGGTSGCVETGCFGKEAYVLTGY
                     MNIPKILELTLNNGYDPISKKQIGIETGDPRNFQSYEELFEAFKKQLHYMIDIKIEGN
                     AVIENICAKHMPCPLMSTIVDDCIEKGKDYQRGGARYNTRYIQGVGIGTITDSLTAIK
                     YNVFDKKKFDMDTLLKALDANFEGYEAILNLVSNKTPKYGNDDDYADEIMQEIFNAYY
                     NEVTGRPTVCGGEYRVDMLPTTCHIYFGEIMGASPNGRLCAKPVSEGISPEKGGDTNG
                     PTAVIKSCAKMDHIKTGGTLLNQRFAPSVVQGEKGLDNMANLVRAYFNMDGHHIQFNV
                     FDKNVLLEAQKNPQDYKDLIVRVAGYSDHFNNLSRTLQDEIIGRTEQTF"
     gene            complement(26079..26987)
                     /locus_tag="KOU88_000022"
     CDS             complement(26079..26987)
                     /locus_tag="KOU88_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBK3209951.1"
                     /translation="MNPLVINLQKCSIHDGPGIRSTVFFKGCPLECVWCHNPESQTYT
                     KQVLYNEERCSKCEACINICPHKAIYKGETKICLDQDKCEFCETCLDYCVNNAREIVG
                     QEYSVRDLVKEIEKDRIFYEESGGGVTLSGGEVMAQDMDFICGVINMCKSKGIHVAID
                     TCGYAKSENYERVAKCADLFLYDIKLIDEDKHIKFTGKSNDLILKNVKILSELGANIN
                     IRIPLIVGVNVDDENLEVKKMIEFLKPLNIQAVSLLPYHNIGKHKYDKIYKKYEGEEL
                     QRPSEEKLEEIKRLFEASNFNTKIGG"
     gene            complement(27332..28411)
                     /locus_tag="KOU88_000023"
     CDS             complement(27332..28411)
                     /locus_tag="KOU88_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBK3209952.1"
                     /translation="MSRRKKGISLVILVAIISSILSSFLTIILVKDNLVSKSTGSSTP
                     IVVNDDGKSQNIYQAVAEKATPSVVGITTTSVDTSNMFAIPTETQGVGTGIIVDSNGY
                     ILTNSHVISDGQATSVNVLFNDGSTTSGKVVWFDQQLDLAIVKVDKTGLTPAEFADSD
                     KVKVGDISIAIGNPLGLDFQKTVTQGIISGLDRTIQTEKTNMTGLLQTDASINAGNSG
                     GPLLNQKGQVIGINTAKASQAEGLGFAIPINTAKSIVEEVIKNGKYEKVTLGIKGTDV
                     SNYEAATGTKLSTDKGVYVAEVISGSSAEKAGVKVGDIITKVGDTDITGMNDLNKKLY
                     TFSKGASTKITVNRGGKAVTINVNF"
     gene            complement(28567..29916)
                     /locus_tag="KOU88_000024"
     CDS             complement(28567..29916)
                     /locus_tag="KOU88_000024"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBK3209953.1"
                     /translation="MGKINFDYSKATEFFCQNEIDVMQPYVDVAHDMLHNKTGLGNTF
                     LGWIDLPKNYDKEEFDRIKKSAEKIKSDSDVLLVIGIGGSYLGSRAAIDMVSHSFRNG
                     LKKEQRKAPEVYFVGHNISSTYIMDLLDIIEGKDISVNVISKSGTTTEPALAFRIFKD
                     YLEKKYGKEEARKRIYATTDASKGALRQLATEEGYETFVIPDDVGGRFSVLTAVGLLP
                     IAAAGLDIDAMMKGANDAREAFQNPDLKSNDSYRYAVARTILHRKGKDVELLVNYEPQ
                     LHYVSEWWKQLYGESEGKENKGLFPASVDFSTDLHSMGQYIQDGKRLLFETVLNVENC
                     KRNITISSEEVDLDGLNYLAGKTVDFVNHKAFEGTLLAHTDGKVPNLVINIPQLDEYN
                     FGYLVYFFEKACGISGYLLGVNPFDQPGVEAYKKNMFALLGKPGYEKEKEELEKRLK"
     gene            complement(30181..31809)
                     /locus_tag="KOU88_000025"
     CDS             complement(30181..31809)
                     /locus_tag="KOU88_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBK3209954.1"
                     /translation="MNIIISLMGGLGLFLYGMNLMGEGLQKSAGTKLKKIIKLLTSNL
                     FMGVLVGTGVTAVIQSSSATTVMVVGFVNAGIMTLKQAIGVIMGANIGTTVTAQLVSF
                     DLTGMAPVALGVGIILYLFGNKPRIKNIAEILIGFGILFTGMDFMKMAVEPLRDYQGF
                     TDLLVTFGRYPLLGLLLGFGITAIIQSSSASMGMLVALAAEGLVPLSAALPILYGQNI
                     GTCVTSLLSSIGANKNARRAAMMHLIFNVLGTVIFLIFLNKPVVSMVTSWDPSNVARQ
                     IANTHTLFNIISVLILLPFTNLIIKLAIKLVPDRAGDIDEDETKTIKYIDDRMIETPS
                     IALANTIKEALRMGEKAKESLNASMEALVEHSTEKIDKTYRRERLINDLQKAILNYLL
                     KLSKAPLDDDSREVVDTLFNTVNDIERIGDHAKNIAELSQVAIDSNISFSEEGQSELD
                     VMYNRVVSAYTYALESMRTDNVDLACKVIKIEEQVDIMEKSCRANHMYRLNNNLCSIE
                     NGVIYLDVISNLERISDHAVNIAQQVIAKRLGND"
     gene            complement(31933..33537)
                     /locus_tag="KOU88_000026"
     CDS             complement(31933..33537)
                     /locus_tag="KOU88_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209955.1"
                     /translation="MLRVSNVKLGIDKDISLLKDVILKKLKIKEKNLVKYSIYKESID
                     ARKKGKMEFVYSVDVEVKDENKILNSKIKDVTKIKEIRYVNVPVGDKKLKNNPLVIGS
                     GPAGLFAGLLLAQMGYEPIILERGLDVDSRTKDISDFWTTRKLKNNSNVQFGEGGAGT
                     FSDGKLTTRIKDIRCRKVLEELVQFGAPDEILYSHKPHVGTDILKNVVKNIRNEIISL
                     GGQVRFNSKVTDIVVSNDSIQSVIINDTEKIDTDTIILAVGHSARDTYEMLYSRGIKI
                     VQKPFAIGARVEHPQDLINKAQYKDFYNHPRLGAADYRLIEHVSNGRTAYTFCMCPGG
                     SVIASASNDFEIVTNGMSEHARDKINANSAFLVNVTPEDFKSDNPLAGVHFQQKYEKL
                     AFELGGKNYNAPVQLVGDFINNKTSLNLGSVEPSYRPGYTLTNLSECLPSFVTETMRE
                     AFISLDKKLNGFAMYDAVLTGVETRSSSPIRIVRDENTLESVSIKNLYPCGEGAGYAG
                     GIVTAAVDGIKCAEKIIQKYTNNTKI"
     gene            complement(33585..33902)
                     /locus_tag="KOU88_000027"
     CDS             complement(33585..33902)
                     /locus_tag="KOU88_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209956.1"
                     /translation="MDYIGIENITPYENTYEFSVYEYDDEITLGSEKLYVCELRVVLI
                     KVNSLYVERLHKSVEAMVLVKNLKKDLDKTLVVNKIKNFVLDEIWVENLVKENIEVIF
                     VES"
     gene            complement(33907..34272)
                     /locus_tag="KOU88_000028"
     CDS             complement(33907..34272)
                     /locus_tag="KOU88_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209957.1"
                     /translation="MSLSLGNAIAVSTNFIKSNPAVPVYNGEEIYAVIYHIEIGYNNG
                     VSPDTKQYIIIDYKEFDLSMDKKNELINIAKEYCKSKGIVENENLEINLLDNEEAENF
                     LEKVFNNMKVIRGLITKKG"
     gene            complement(34353..35390)
                     /locus_tag="KOU88_000029"
     CDS             complement(34353..35390)
                     /locus_tag="KOU88_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBK3209958.1"
                     /translation="MLGRNELCPCGSGKKYKKCCLNKDIVSERACRKTELSQKQYTDL
                     YSKLYDYSRQDKFKEECEKAKEMFYIMQNDSVNEKFERFFNTYLIQDHIMENKKVMTV
                     GFLEENGANLSQSEVSILKSMFESYVSIYEVKEVSAGKIVLKDCLSGNELCTEDVKLL
                     RSFKIGSCMIARIVDIEGTNILIDITISISNEVKDIILKDIMNLFNQYQDVYKDMKSF
                     LIYHTHILYKYIQQLLDPSIAEYLKRERDKNDTKVNSENELAEEECKVLDTLKENVEK
                     ENIDACIEFWNEYKKNHENIKGAENGWAAAVEYYVKKEAGQPITQVQISKKYDISSST
                     LGKRYKDLKIS"
     gene            complement(35643..36227)
                     /locus_tag="KOU88_000030"
     CDS             complement(35643..36227)
                     /locus_tag="KOU88_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209959.1"
                     /translation="MRLNNREKNLLKILLILVIILASDIAVSYLEENLTSLKNEKQNI
                     INKINNQDNYQIKDNKHIDDKYIESVESNKNEELKNNFNNSFLDKKTNKDIVLLVENE
                     LRDIVNVEYINQESSLDNHNKKQVNLEIKVNGELANVLKLEGVMKKLRLNNKLEKIEI
                     NKLKVNNFDVQNIPNEYKQEKDNIVECKMTVRVI"
     gene            complement(36242..36685)
                     /locus_tag="KOU88_000031"
     CDS             complement(36242..36685)
                     /locus_tag="KOU88_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209960.1"
                     /translation="MKVDKTINFLNGFKKTKPCNKIYKIIIVLILTCILFKSFMYVKS
                     INELEDYISQNKLVDKSRHTLPTTDKTREKFSKIKLNEIKKIYETIGINSITKISIDK
                     NKLEMEGVCSDLDVLNNLRKIKYIKYYYIDSIVRDGEYYRFRIKS"
     gene            complement(36686..37558)
                     /locus_tag="KOU88_000032"
     CDS             complement(36686..37558)
                     /locus_tag="KOU88_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein PilM"
                     /protein_id="HBK3209961.1"
                     /translation="MAIIKKILNLEINDDYIRLVFLRKGHKKVFIDKSIIKEINFDIK
                     NDSNSIEKIKYIEDVVRFVKEEIGKSKILYKNLYFNIQIQDIVIRNVEVLNTKKKRDI
                     LSMIEFEITQYIPININNYSIKYKVINSKNDKLNIQVILFPKSIIQLIKNISENLNMN
                     PKTININFDILQKLINLNLIENFSEEGVFIECKKSQLIINITKDKKIRETYLLSKEGK
                     SYEFIKRLLRDFKYVYYYGIENCFIEEYFKYTDKSIEVNPLRLKDKVKVENNFDADLE
                     DNRINYINSIGMII"
     gene            complement(37611..37970)
                     /locus_tag="KOU88_000033"
     CDS             complement(37611..37970)
                     /locus_tag="KOU88_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBK3209962.1"
                     /translation="MINLINKKRKGFTLVEMIVVVTILGVISSIALVKYSKVQESAKL
                     NADYTNAANIVTAASMAINDDEKTIDSLSVETLKEKGYLNTVPVPQSTSGKFELVIND
                     SGTDISVNINSKQFYPK"
     gene            complement(38024..39109)
                     /locus_tag="KOU88_000034"
     CDS             complement(38024..39109)
                     /locus_tag="KOU88_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBK3209963.1"
                     /translation="MRLSKNIFYNLEKFYLVLNRISDKEIRVICKEIGILLESGCEIT
                     KIFEIIESQSSKKVKNLLSIVSNHIQKGNSIAESFQITGIFSKFFISMIKAGETSGNL
                     DIIMSDLSNYYDKEYKLKMKIITISIYPIILIILSILSMLFIFVFVIPNFQVVFTNNG
                     IEPPLITRVLMGISTVVTNNLAYIIFSFILFSIGSIYFFITNDNIKKLINSLKFKIPF
                     IKKINQLVATTRFSRALSVLISSGIQIVEAIDMSASVIDNEFIYERLKISNNYIKKGN
                     SIGKSLNLANIFPKLFISMANTGEESGKLDKSLNVINKFYENELNNKIEQIMKFIEPM
                     LIVFMGLIIGTFILAMVVPMFDAITNF"
     gene            complement(39280..40659)
                     /locus_tag="KOU88_000035"
     CDS             complement(39280..40659)
                     /locus_tag="KOU88_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBK3209964.1"
                     /translation="MIKIILEESSLPMLIPEKLAKKYNVFPVEFQDDNLVVEIEDEDI
                     YALQDLRLATGKEIILKKEKKELISEKIEKYYNSFELDEDYAKKLFENLLEKAIKENA
                     SDIHIEPFKEHLIVRMRVDGELKEVSKFLVDVYPSLSTVIKLKASMDITEKRLPQDGR
                     VDIKLGGNLIDIRVSSIPTVYGEKIVLRILNRDTFLKDKLELGFSEEAIKSINRIINK
                     RAGILLVTGPTGSGKTTTVYSLLNDLKGINKNIMTIENPVEYKMDGISQIQVNSKVGL
                     SFDVGLRAILRQDPDIIMVGEIRDAETAKIAVRAAITGHLVISTLHTNDAVSSIARLL
                     EMQIPPYLLNASLIGVISQKLVRKVCNHCSHEIMIKDNFSGDVNTKVAVGCEKCNDKG
                     YFGRTAIYEILEINDDIKTCIRNMEDSSTIKDVAQNNGMITFEDSCKRLINEKITTLE
                     ECLVVNEMI"
     gene            complement(40652..41332)
                     /locus_tag="KOU88_000036"
     CDS             complement(40652..41332)
                     /locus_tag="KOU88_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBK3209965.1"
                     /translation="MKKQYVFIILASTILGILVGTIFRDYSNEETVYTSKDKSIRKEI
                     KMTRKSIKELTKEKDKLDKEINSMKQNQKNSEEISEIETLRDSLSYSDVKGSGIILSI
                     DAIDEKTGNIANSIDYNKILVKVINELKVNGGKYIEINGQRINQYSEVVLAGSHININ
                     GVPVAQPYEIKCIGDKEKLSNYVDKGSKYLDSIQTNYPMKISIKTEENISMKKMNIPN
                     KLKYIKGD"
     gene            complement(41723..42802)
                     /locus_tag="KOU88_000037"
     CDS             complement(41723..42802)
                     /locus_tag="KOU88_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3209966.1"
                     /translation="MEGKVKKAFPGGNTSQGSYSFFDYIIPENVKRVFCLKGGPGVGK
                     SSLMKKIYKEFLHRGYDIDLYHCPSDPSSLDGLVIKKLGVVLMDATAPHTMDPKLPGA
                     LDEIINLGDYWNTEELEKNKQEISVYDKDISNSFKRAFKFLKSAEPIFRDIEEKYSDC
                     MDYGKVNLVTEEFIKRLFDGVKSTGNLKREKHLFGSAITPVGCLDYTENILKDVKKVY
                     YLDGEIGTGKTTLLNKVYKKAIEKGLNVEVYHYPLIPEKIETVLLTDLDIGITISTTF
                     KEEDTIDLNQFLNREKLLKYEEDIKFDEKVLDDLICWAVLNLKRAKSKHDIIESYYSP
                     NMRFDEVGKLRDKLIKRILKYEENL"
     regulatory      43090..43205
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            43380..44750
                     /locus_tag="KOU88_000038"
     CDS             43380..44750
                     /locus_tag="KOU88_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3209967.1"
                     /translation="MKQKWIVLIIICIGVFMSTLDGSILNIANPTIAADFKINMSQIQ
                     WVVTAYMLVVTATMLFFGKLGDKVGSNRLYTLGFFIFTIGSFLCSMSNNLSTLISSRI
                     FQAVGASILMATGLGIVSNAFPANEKGKAIGITGAVVGIGNMSGPVIGGIILEHFGWP
                     SIFIINIPIGIIAVFLGIKFLPKPVLDEQNKSFDIPGLLLFASCTTLILLAMNEKGNT
                     RLYLGITALIIFLLLALREVKFEQSFIDLPLFKNRNFTVGNIIGVACYFPQMAVSFLL
                     PFYLEQLKNLSPMMAGYVMTVHPLIMVLIAPIAGSLSDKHGAKNILTASFSFMTISLV
                     GMALLKADSPLYLLIVCLVIFGLGLGAFSSPNNSSILADVPPQKQGYGGSFLATIRNL
                     SFALGTAFFSSFFAQSLTYNQKFKSHTSAYVIASNQSYWIAASVCFIGLILTVFFMRK
                     TDKSIS"
     gene            complement(45015..45626)
                     /locus_tag="KOU88_000039"
     CDS             complement(45015..45626)
                     /locus_tag="KOU88_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBK3209968.1"
                     /translation="MKIRSSEITMSAVNKSQYPAEGIPEIALAGRSNVGKSSIINTLL
                     NRRNFARTSQTPGKTRTINFYLINNEFYFVDLPGYGYAKIAKSEKEKWGGIMERYLES
                     RQELCSIFLLVDIRHEPTADDKLMYEWIKHFGYNCVVIATKADKISRGQYQKHISIIR
                     KKLQMESSEKVIPVSSLKKTGVEELWEEIVNQYNQHGYEITVD"
     gene            complement(45616..47979)
                     /gene="lon"
                     /locus_tag="KOU88_000040"
     CDS             complement(45616..47979)
                     /gene="lon"
                     /locus_tag="KOU88_000040"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBK3209969.1"
                     /translation="MEQNYTKIDHELPLIPLRGLAIFPYMILNFDIGREISLKALDQA
                     MMDEELIFLTSQKEAEVDEPGEEDFYHVGTICKVKQMIKLPGDTVRVLVEGVSRGRVK
                     KIEQEDGYFRAVIEEIVFDSDNLDSETEVEIEAFVRNVFDAFEEYINIGNRVSPEILI
                     SLADIEDVDRFIDTIAANIYLKSSQKQEILEEFDIRKRLELIYSILLEEIDILKIEKK
                     ITLRVKKQMNKVQKEYYLREQLKAIQKELGEEEDINSEADEYREKLKKIKAPKTTKEK
                     IEKEIDKFSKISSMSPDVSVSRNYLDTIFSLPWNKETKDKLDITKAKDILDEDHYGLE
                     KVKERILEYLAIRTLAKSLKGPIICLVGPPGTGKTSIVKSIARALNRKFVRISLGGVR
                     DEAEIRGHRRTYVGSIPGRIINGVKEAQTKNPVFLFDEIDKMAADYKGDPASAMLEVL
                     DPEQNKDFVDHYLEIPFDLSKILFVTTANSLSNIPRPLLDRMEVIEVSGYIEEEKLNI
                     AKKYLLPKQIKEHALKENFIKIDDETLRSIINHYTREAGVRTLERTIGKICRKVAKKY
                     VEDPTLEEVVINKSDLETYLGKDMFKYQLAEVNPQIGLVNGLAWTEVGGVTLEVEVNV
                     LKGKGEIVLTGKLGDVMKESAKTGISYIRSIVDKFDIDPEFYKTNDIHIHIPEGAVPK
                     DGPSAGITMALAVISALTKRPVPGNIAMTGEITLRGRVLAVGGVKEKLLAAHRAGITK
                     VLIPKECEADLDEIPENVKEKMEFVLVEHMDEVLEQALLKSGENNEN"
     gene            48159..48671
                     /locus_tag="KOU88_000041"
     CDS             48159..48671
                     /locus_tag="KOU88_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBK3209970.1"
                     /translation="MLKLFLTFLKIGAFTFGGGYAMVPLIQDELVNKQKLLEQEEFID
                     YLSIAQSYPGVLAVNISVLLGYKLYGIPGVLICTLGSALPSFCIVLVLSYLYFKNSSS
                     KILDGFFKGVAPVVIALILYSFTSMFKKLPKSKTNILLLIIAVLSVGVFNISPIYLII
                     GGGVYSLCQK"
     gene            48659..49186
                     /locus_tag="KOU88_000042"
     CDS             48659..49186
                     /locus_tag="KOU88_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBK3209971.1"
                     /translation="MSEIILLFLIFLKIGAFSFGGGYAMLPFIQQEFISKYHFITNQE
                     FLDLLAISQSTPGPVAINSATFVGFKTAGFFGSLAATIGVTIFALIGLTIISKLFSKF
                     KNNKKVENLLTVLRPITLGFILSAAFSSAKEVNWDLYGIIAFIASFYLLYKGKIGSIA
                     IVFVFGILGILLTFL"
     gene            complement(49257..50507)
                     /gene="clpX"
                     /locus_tag="KOU88_000043"
     CDS             complement(49257..50507)
                     /gene="clpX"
                     /locus_tag="KOU88_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBK3209972.1"
                     /translation="MSKYEEKRQLKCSFCGKNQDQVRRLIAGPNVYICDECVELCDEI
                     IQEEIEDTIDEDTTSLPKPKEMMEILNDYVIGQEKAKKALSVAVYNHYKRIYSKKSSS
                     KDIEIQKSNILLLGPTGSGKTLLAQTLARTLNVPFAMADATSLTEAGYVGEDVENILL
                     KLIQAADFDIEKAERGIIYIDEIDKIARKSENPSITRDVSGEGVQQALLKILEGTVAN
                     VPPQGGRKHPHQEFLKIDTTNVLFILGGAFDGLEKIIQKRGGDKTLGFGAKIESKKEL
                     DLGKLYEKVLPEDLLKYGIIPEFIGRIPVLATLELLDEDALMQILQEPKNALVKQYKK
                     LLELDDVELEFEEGALRAIAKKAIERNTGARGLRSIVESVMMETMFEVPSRDNIKKVI
                     VTEKSVNEDSVNPIIVLKDQEESA"
     gene            complement(50526..51110)
                     /gene="clpP"
                     /locus_tag="KOU88_000044"
     CDS             complement(50526..51110)
                     /gene="clpP"
                     /locus_tag="KOU88_000044"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBK3209973.1"
                     /translation="MALVPVVVEQTGRGERSYDIFSRLLKDRIIFLGDQVNDATAGLI
                     VAQLLFLEAEDPDKDIHLYINSPGGSITSGMAIYDTMQYIKPDVSTICIGMAASMGAF
                     LLAAGAKGKRLALPNSEIMIHQPLGGAQGQATDIEIHAKRILKIKETLNEILSERTGQ
                     PLEKIKMDTERDNFMSALEAKEYGLIDEVFTKRP"
     gene            complement(51260..52546)
                     /locus_tag="KOU88_000045"
     CDS             complement(51260..52546)
                     /locus_tag="KOU88_000045"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBK3209974.1"
                     /translation="MKAELIKKEGNKVTLKITVDNNKFEAAVNKAYNKSRNKYNIPGF
                     RKGKAPRIVIETQYGKGIFYNDAIEILFPEVYPEAIKELDIDPIDNPDLDIEEISKDN
                     GLVMVLNVEVKPEFELGNYKGIEIAKVENTVSDENVDAKLQEMVEKNARLVSVEDKAL
                     EDGDTAIIDFEGFENGVAFDGGKGENYNLVIGSNTFIPGFEEQLVGKKAGEEVEVNVT
                     FPEEYHSQDLAGKPVVFNVKINDVKVKELSALDDEFAKDTSEFDSLDELKADVRAKLE
                     EEAKNRADAETRNSVVEKVAENTEIEIPEVMIQHQIDNMLNELNYQLQYQGFGLQQLL
                     EMTGRTMEELREERKEDAKKLVKSSLVLEAITKAEGIEATEEEFKAELEKMASAYNME
                     VEKIEASLRDADKEDIKGQIKIRKTIDLLVDNATIA"
     gene            complement(52740..53210)
                     /locus_tag="KOU88_000046"
     CDS             complement(52740..53210)
                     /locus_tag="KOU88_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK3209975.1"
                     /translation="MKIGIVSDTHMMIKNMEKTIPYLKECDLIIHAGDNFTDSRYIHS
                     MTNVGIIAVKGNCDFDAVEEEVVFEVANKTIFLCHGDKYGVKYGTNMLEKKATEVDAD
                     IVIFGHTHTPFREIKDGVLYINPGSTSLPRGVSYKSFVIMDIEEDDIKIEEIRI"
     gene            complement(53210..54559)
                     /gene="rph"
                     /locus_tag="KOU88_000047"
     CDS             complement(53210..54559)
                     /gene="rph"
                     /locus_tag="KOU88_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBK3209976.1"
                     /translation="MTRSYDRSNEQIRPVKITRDYTKYAEGSVLIEMGETKVICTASV
                     EEKVPPFLRNSGTGWINAEYSMLPRATQQRKIRDASRGKIDGRTQEIQRLIGRAIRSV
                     VDLNKLGERTIWVDCDVIQADGGTRTASITGAFVAVAEAIYKLYKAKTIKEMPITNFV
                     SAISVGIVNGIHMLDLCYEEDSKAQVDMNIIMTDKCEFVEVQGTGEEKPFSRADLNLL
                     LELGEKGNKELIRLQREALGEISDEILGMDYGNEVVIATNNAHKLEEIGEILKDFEYK
                     VYSLKDVDLAGIEIVEDGKTFEHNALIKARTIAKKTKLIAISDDSGLEVDALGKKPGV
                     YSARYAGEHATDEENRKKLLKAMQNVPMSKRNARFVSAIAVVFPDGKEFVVRGICEGM
                     IGFEEKGKNGFGYDSLFIVKGYDKTFGEIPSVIKNSISHRANALKLMKQEFIKRVVK"
     gene            complement(54719..56743)
                     /gene="ligA"
                     /locus_tag="KOU88_000048"
     CDS             complement(54719..56743)
                     /gene="ligA"
                     /locus_tag="KOU88_000048"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBK3209977.1"
                     /translation="MSVKDEINKLIETINYHNERYYNQDSPEISDYEYDKLMKELISL
                     EEEHPELKKIDSPTNRVGGKPLDKFNQIVHKTPMLSLSNAFSEQDLRDFDKRVQEYVG
                     ENVEYVVEFKIDGLSVGLTYNNGEFEKGATRGDGVVGEDISQNLMTVKSIPLKINDKK
                     ELIVRGEVYISKDNFRKVNEQQEEQEQPLFANPRNLAAGSLRQLDPKLTAKRPLDIFV
                     FNMENIEEYDLESHSESLEYLEKLGFSVSQSYKVCKSIDEVIEHIEYWTDNRGNLDYE
                     IDGMVIKVNNIKQRDEMGYTAKSPRWAIAYKFPAEKKKTKIVDIIVEVGRTGTITPSA
                     ILEPVRLAGTTVSRATLHNEDYIREKDIKINDTVLVQKAGDIIPQVLEVIKEERTGDE
                     IDFKMPEKCPVCSEPTIRLEGEAAVKCINMSCPAQIRRGIIHFVSRDAMNIDGLGESI
                     ITLLLNEKIIQDVSDLYYIKKEDVVDLERMGEKSADNLINSIEKSKENDLWRLINGLG
                     IKFIGVKAAKILAYNFKDLDEVISATSEQLEELEEFGSIMANSVVEFFKEDKNMNVIN
                     KLKNVGVNTKSLDNTGEKVEKIFEGMKIVLTGTLPTLKRNDAKDMIEKRGGKATSSVS
                     KSTTFVLAGEEAGSKLTKANDLGIKVIDEERFLELLKLSSKDEVKAVLES"
     gene            complement(56929..57867)
                     /locus_tag="KOU88_000049"
     CDS             complement(56929..57867)
                     /locus_tag="KOU88_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBK3209978.1"
                     /translation="MKVLFTINYGKEKFDKIRELGYDVIHYSEDSIENNEDVNTADVL
                     VTYNPFERLDISKMKNLQYIQTTSVGIDQLPKEEVLKRNIKIANNRGGYSVPIGESIV
                     LYILEIYKNSAKFFKQQQNKEWKMDFSVSELYGQRVGFLGTGTISSEAAKRLKAFGVE
                     IWGVNTDGSSKKYFDKCFAAEDMNIVFEECDIVVVAMPSTKSTDGIVNKDMFKLMKDG
                     SVFINVGRGNTVNQKDLEECVEKFRGVALDVFESEPLNKDNKLWECENVIVTPHNSWV
                     SDKNKERTFNMVYNNLKHYIMENKPVDNVVDISRGY"
     gene            complement(57969..58391)
                     /locus_tag="KOU88_000050"
     CDS             complement(57969..58391)
                     /locus_tag="KOU88_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3783 domain-containing protein"
                     /protein_id="HBK3209979.1"
                     /translation="MSFEKINNNNLDKIHNRKCIMLVNFNKKELSLIKNVSNFAGIRD
                     HIILSDKNGENIIRDILDGNISNECENGIKSKSVIFNNTPSTQVNAFLEGLKKVRINR
                     PFTAMVTETSIDWTLNNLIENLVQERNAMSLGKTIEHK"
     gene            58579..59862
                     /locus_tag="KOU88_000051"
     CDS             58579..59862
                     /locus_tag="KOU88_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugated bile salt MFS transporter"
                     /protein_id="HBK3209980.1"
                     /translation="MNTLLNNKFSIKNFSNAWVIVLGCMLIQAVPFSIVASIQPQFIS
                     YVVEGEGFSLASFSLIFTIGTIASAIASPFIGVLFSKVNIKILYLLGCIISSIAFATF
                     SICTELWQFYTVSCIVQIGATIISAIGIPVLISAWFDEESKGKALGFAFAGGSIGSIF
                     LQPLAVRLLATQGYSRSYLIFGIIALIVGIPVILFILRMPKDINEKVKSKGKKEKASD
                     TISPSVWGYTLKEAKKIKYFWIMTIGFIFVGIYVSSLSVQYPTYLRNYLNPILIGTVG
                     STFALFALIGNLFGGLLFDKFGQTKPLIISFVLVLIATLSLLLVDKSSTFAFVFAILK
                     GLSVFAYMIGPAYLTGSFFGQKEFGSIYGIVQLIFAVGFALGSTLFGLLVDNFGYRFS
                     WSIIILSVIIAYTLLIITSIGMKKLNKERLDKLMQ"
     gene            complement(59940..60455)
                     /locus_tag="KOU88_000052"
     CDS             complement(59940..60455)
                     /locus_tag="KOU88_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBK3209981.1"
                     /translation="MNYFVIADPDKCIGCRTCMIGCVVAHSDEDIFYQNPDEINFNPK
                     LSVIKTKEVSAPIQCRHCEDAPCAKACPNGGIVRVGNTIKINEENCIGCKTCMLACPI
                     GAIDIVTLKDVDEGKLCFRERMTANKCDFCIESPEGPACVNVCPTKAFTIVKDEDIDS
                     KVKNKRKLAIL"
     gene            complement(60455..61831)
                     /locus_tag="KOU88_000053"
     CDS             complement(60455..61831)
                     /locus_tag="KOU88_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBK3209982.1"
                     /translation="MIINIDKDLCTGCRECSKVCPVNAIEGEEGKPQEINLDRCVMCG
                     QCVQTCKSYASVIDEGFEFLQEKKQEREIPESINEPIFAAYNVCDIDKVKKALSDPNV
                     FTMVQCAPAVRVALGEDFGYYLGYLGAGKMAAALRALNFDRVYDTNFAADLTIMEEGS
                     ELIKRVTEGGTLPMFTSCCPAWVKFMEKNYPKLTNHLSSCKSPQQMGGAIFKTYGAEI
                     NNVDASKIFSVSIMPCTCKKYECDREEMDSSGYRDVDVVLTTRELAYLIKDMGIDFKN
                     LREEKFDSPLGSYSGAGTIFGVTGGVMEAAIRTGYELITGESIPDVEVKQVRGENGFR
                     KSTIKIGDLDLRVGVVSGLKNVIPVLEDLEKGKLDVDFIEVMTCPVGCVSGGGQPKIL
                     LEEYKELAYENRTKATYVHDEHLAIRKSHENPDIKKLYDEYLVEPLGEKSHHLLHTTY
                     CIGKEVAK"
     gene            complement(61856..62407)
                     /locus_tag="KOU88_000054"
     CDS             complement(61856..62407)
                     /locus_tag="KOU88_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBK3209983.1"
                     /translation="MKNKIGSFVIADPNKCTGCRACEVACFTMHNQHNNVGYTVGTVD
                     IPVIPRLYLVKGDNFCMPIQCRHCEDAPCLNSCPQKAIVKENNIMSVNEEKCIGCKTC
                     LLACPFGAIDLLPQYEDGKEVEQVILDENKKIAYKCDLCKDNEKIACISACPQEALKL
                     VTPIDDKKAKNRQAALSLLLTNK"
     gene            complement(62444..62659)
                     /locus_tag="KOU88_000055"
     CDS             complement(62444..62659)
                     /locus_tag="KOU88_000055"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209984.1"
                     /translation="MQIHRELSKSENEYMCTKKEEQRYSKCEICGVLIDDTDKVYNNT
                     YNLCKKCKRNISTEKIVKYINIYDENN"
     gene            complement(62628..63461)
                     /gene="fdhD"
                     /locus_tag="KOU88_000056"
     CDS             complement(62628..63461)
                     /gene="fdhD"
                     /locus_tag="KOU88_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBK3209985.1"
                     /translation="MNNIYSKTKLQENSKDKVFENSYSLVDYKYLNSFNVEVSKINEH
                     EVSIDNEEIIAEYPLSFILNDKYINTFLCTPYNLEELIVGFLKTKGYIENKKSLLKFE
                     INESERFAKVTIQEKQKNQDEQIIFLNSLDYITCAPVKSNIKINYDTIYSIMDKNLNS
                     SELFKNTGGVHSVSVFNFDKKIVTCEDVARHNAMDKAIGFCVLNDITLKDKIVAVSGR
                     ISLEMILKAAMTQIPIVVSKSAPTNLSIELSKKLNITLIGFVRGRRMNIYANPQRVIK
                     K"
     gene            complement(63510..65654)
                     /gene="fdhF"
                     /locus_tag="KOU88_000057"
     CDS             complement(63510..65654)
                     /gene="fdhF"
                     /locus_tag="KOU88_000057"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(65238..65240),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HBK3209986.1"
                     /translation="MEKKILTVCPYCGAGCQLYLVVKDNKILRAEPANGRTNQESLCL
                     KGRYGWDFLNDPKILTPRLKKPMIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSI
                     MGTGSARGPGNEANYIMQKFMRATIGTNNVDHCARVUHAPSVAGLAYSLGSGAMSNSI
                     PEIENADVLFIFGYNGADSHPIVANRIVKAKKNGAKLIVTDPRVTESARIADIHLPIK
                     GGTNMVLVNAFGNVLIEEGLYNKEFVQNHTQGFDEYKEIVKPYTAKYAEKITGIPEEL
                     IRKAMREYAKGKKAMILYGMGVCQFGQAVDVVKGLASIALLTGNFGRESVGIGPVRGQ
                     NNVQGACDMGALPNVYPGYQNVTDDKIREKFEKAWGVKLSPNNGYSLTQVPDLVLKEK
                     KLKAYYIFGEDPVQSDPDASEVREALDELEFVIVQDIFMNKTALHADVILPATSWGEH
                     EGVYTCADRGFQLMRKAIEPQGDVKPDWQIISEISTAMGYPMNYKNTKEIWDELRQLC
                     PSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLYEGQKFSTPNGKGNLFAAEWRPPM
                     EVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLEDEPGRVQINSNDAEKLGIEDDE
                     LVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNELTIANLDPISKTPEYKYCA
                     VKLEKLEDQELAEKCVREEYQSLKDKMTATNI"
     gene            complement(65905..66963)
                     /locus_tag="KOU88_000058"
     CDS             complement(65905..66963)
                     /locus_tag="KOU88_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBK3209987.1"
                     /translation="MDRLKNIRKSLLQYTFLFLLIGITIYLVFKTLDIKMLSNVMVMV
                     DKKFLFIGALAIMCHIMLEGVVMKIIIESTHKVNIRFIGFKLAIMGFYYNLITPFASG
                     SQPVQIYVLKKCKMPLSKASAVVTNKSIIFQIVVTFYCTILVLMNFAMLEKQMKMIMP
                     LVFLGIAINSFVLIMIILVILNPKKIKYFMRITIKHLSKIKFLKFLDNKIESIESFID
                     DYSKAINFFAKNKKVLISTIIVTFIQLSAYFSVSFWIYKAFNLQGYSYIYILTLQAFL
                     YMAISPIPTPGNVGANELAFFTIFKSVFPQPLMGYAVFLYGGFMYYLILIGSGIFTVI
                     THYRMKNRIGRNIVLSEN"
     gene            complement(67174..67833)
                     /gene="cprR"
                     /locus_tag="KOU88_000059"
     CDS             complement(67174..67833)
                     /gene="cprR"
                     /locus_tag="KOU88_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CprR"
                     /protein_id="HBK3209988.1"
                     /translation="MSKILVVDDELDMLKLIENVLKRDGHEVKVISDVEKAMNMDFNY
                     FNLIILDVMMPKMDGFEVCKTIRNKVDCPILFLTAKNMESDIMYGLGIGADDYITKPF
                     GVGELRARITAHLRRESREKKNLLTISNVQFNFLGKEVSIDGKKINFTKSEYLICEFL
                     AKNKGQVFSKERIYESVYGFDGESDISTITEHIKNIRSKLKQYDIYTIETVWGIGYKW
                     V"
     gene            68139..68768
                     /locus_tag="KOU88_000060"
     CDS             68139..68768
                     /locus_tag="KOU88_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3786 domain-containing protein"
                     /protein_id="HBK3209989.1"
                     /translation="MDEKITKNNYNVPFDYVRKKLKELDPHTISNLSNIPFNNDLNRF
                     TLNFFDRQYIIDYPSGEVWNSNGSLCNNFELKILIVRYLINAKGIPRTNKYVTFKEIP
                     GGNVYYPNFLNRTLYRLSEVFTSQIDKYKLVMEKIGAEKVNMGDLAYRFTYMGNTSMI
                     FILWFGDDEFPPNSNILFDSNIVYYFNAEDLAVVPDTAINAILNKINQL"
     gene            68795..69433
                     /locus_tag="KOU88_000061"
     CDS             68795..69433
                     /locus_tag="KOU88_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prenyltransferase"
                     /protein_id="HBK3209990.1"
                     /translation="MIFSTWREDGRFKLYPNGGIYPCHTANAANVLCHMGYASDIRMQ
                     KTFQHFLDTQYTDGGWRCNKFSFGRGPETEYSNPLPTLNILNAFRFSNYLNKESKLDK
                     AVDFLLDHWTIKKPIGPCHYGIGTLFMQVEYPFRNYNLFLYVYVLSFYNRAKKDNRFL
                     EALKILESKMIGNKIVVERVVPKLSKLSFCKKGESSEIATTHYYEILKNLEK"
     gene            complement(69529..70317)
                     /locus_tag="KOU88_000062"
     CDS             complement(69529..70317)
                     /locus_tag="KOU88_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209991.1"
                     /translation="MCILELIKFELKKIELKHVLIFVIISILCIFITGILDYNELIFY
                     NDVPIMDTYSIAGWLGIIKISDVFIPIMSAITIIYVFSKDYSGNINEILTLYNKKKYN
                     QFIVFRWCVILAIYTVLLLISITIVYTFTSVKGFNIDKIDFVYSVKPIDVFLKTFPTL
                     LWYTTFPLMILTLTKNRFTTIAILITYTFADIFFILHMYPFVSMINVNGFYIQKMFYM
                     PNNIDVRFNELKNYFFINRGSLVVISIIIVFYIARKSTVLKKSK"
     gene            complement(70318..71190)
                     /locus_tag="KOU88_000063"
     CDS             complement(70318..71190)
                     /locus_tag="KOU88_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3209992.1"
                     /translation="MINKLEIRNLNFNYKNKKALDNINLTLTDGVVALLGPNGAGKST
                     LMRLLVTLYETSIGEIELNNIKYSKNNEKIKANVGYVPQDFDMYNNINGQEYLEFVAK
                     MRGVSKNDLKKHIQKVVSKVNLDKFINKKIGTYSGGVKRRLGIAQALIGDSKLIVMDE
                     PTVGLDPEQRNEFRRLLPEISKNSIVLISTHIVEDIQFNCDKLIILNQGKILYDGTIN
                     KFIDMVEVYSVVVSNDEFEYLERNIDIIDYRRVKDGVQVKYIGKNTEKLKDSLRIDTT
                     LQDAYINFLHKELK"
     gene            complement(71205..72914)
                     /locus_tag="KOU88_000064"
     CDS             complement(71205..72914)
                     /locus_tag="KOU88_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209993.1"
                     /translation="MSSIKVISDFITKIIRKNILFAITIIIINYHLIQRWTHISNRGI
                     SFNDYLSLSVYTCMTISILTMLNVIFYMRKSYDTVKILCRNNFDYFLGISVAVTRNNF
                     IFCCIPIIYAIAYSSLIRTLSIVTIKSTIFILIFEWFLPLTILSIVISFISVIINNLI
                     LKITLSSVFLYLTSTKMLDRVIDIKEPFFKALFKSLNIFEDQSYAYYSDFVGKVNNSA
                     YVIDKIIPTLFAITLIIVAYLILNDIRKKQIKSLIVIVVYSILFIGLNYISIDMSTYR
                     DEERSYGEYLKKSNISDIKIKSHDMKIDFKSKSNIKDRIVLLNTSNEELTNINMILDE
                     IFDIKYIKVNSENIKFNKKKDLIEVNLKESLEPNDEVTLDIEYEGYINVLTSWNQNKY
                     IATKDDIMLPPGSLAWYPKVNQSSYMAYKINLSSKSNVYSNLPLLNKTSNFLKKDYIF
                     EGKSNDIAIYAGEFKEEVKDDIKIIYPSDSNVNMDIEEKIKFLIETRNEILGDSKASV
                     DAKKYVDEVDNVMESIKRKKINMILVADLPSNEFLYEDSKGEKISITIYHWLSGNILI
                     IDK"
     gene            complement(73061..73642)
                     /locus_tag="KOU88_000065"
     CDS             complement(73061..73642)
                     /locus_tag="KOU88_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBK3209994.1"
                     /translation="MFKRLSYKFANILVNNEIVESEDFEIYRYGFETLIYFIVNILVA
                     LFIGIIFDRFIHTVIFLSCYCTLRQFTGGYHARNYKECTLTFAVIYLITIFSANNIDI
                     NKYKYLLVLLMIISILTIYKLAPLEHRNKPLSESEKKHYRKTVQKILFVIICLIILCK
                     ILNIFQQYVIYAIISIYWIAILIYIGMKVNSDQ"
     gene            complement(73701..73841)
                     /locus_tag="KOU88_000066"
     CDS             complement(73701..73841)
                     /locus_tag="KOU88_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBK3209995.1"
                     /translation="MKKIALNLLKNISALSFGIAVLSANSASSWVAHQAKEPQALQKL
                     KK"
     gene            complement(73853..75169)
                     /locus_tag="KOU88_000067"
     CDS             complement(73853..75169)
                     /locus_tag="KOU88_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK3209996.1"
                     /translation="MLTNLSVGFWNIINLVSGTIDWIIFFLVIHLVGKRKISNIRYIF
                     TTIIIIIFMAYINVVKVFPNIKILLCMVIGISFYITSYEDKIYKSIIVSLLFWLGLMV
                     AEGSAVGLVVFINKLNNINITQHENLFRIQAIIMSKVFLFIGFILFKYFKLSLDFKPK
                     DMILIGIPILSNIVSLLLIFEYNLRVNTITTENLFIFIFAILLILSSSIILLIVIGKI
                     VQDDKLNLEYELINERIKTNYRNYENINEVHDRLKYVYHDLKNHMICIKNYDTKEEII
                     SYINNLEFQISEFEHFKNTGNKTLDLILAEKISICKKYDIQIEDNINISKLNFIKNND
                     ICSIFANSLDNAIEACMDINNEIEKRIEVKATYINKFAIIKFINTKVNDIKLIDKRIQ
                     TSKDDDKIHGIGLASIKYIVNKYGGETIVNYSDNEFILKIMIPIKS"
     gene            complement(75163..75873)
                     /locus_tag="KOU88_000068"
     CDS             complement(75163..75873)
                     /locus_tag="KOU88_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3209997.1"
                     /translation="MINIGICDDELHYRIKIKDILSEILSSYPINYNIYEFSAGEELL
                     NNYPKDLDILIMDIQMKTINGMDTARKIREFDHKLEIIFVTSFVEFMQEGYEVKAYRY
                     ILKPINKEKISKSVLPCINEMMKKRNNYLTINVKNYVDRIKIDSITYIETDRPNILIY
                     THDDMYITKMSISKIEKILNEYGFFRCHNSYIVNLKLVESMSGSTVIVDGKSIPISKY
                     RVKGLKLAITNILGDIVC"
     gene            complement(76312..76887)
                     /locus_tag="KOU88_000069"
     CDS             complement(76312..76887)
                     /locus_tag="KOU88_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1062 domain-containing protein"
                     /protein_id="HBK3209998.1"
                     /translation="MKKITWEVEYISRLPVIRYCKKCGKKTEYICSGLFRVNAQHKYL
                     DIWLIYKCSNCDSTWNSTIYSRVNPKSLNPEILEQFHTNDYNLVKQYAMNMELLHRNG
                     AEVGIPEYKIVGQEININDLTQVHIISKYPCQLKVSTLLREKLGLSRKVFDEMLDCGI
                     IRSNSGVDLKKGKLNYEIMLDIGKEKQKSSN"
     gene            complement(77180..77458)
                     /locus_tag="KOU88_000070"
     CDS             complement(77180..77458)
                     /locus_tag="KOU88_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3209999.1"
                     /translation="MSYKKAIHILPEELLELIQEYVDGECIYIPRKSNNKKEWGSNTP
                     TREELSIRNMQIYEDYQVGYDLQYLSEKYYLSLKSIQRIVLQEKRKDI"
     gene            complement(77767..78528)
                     /locus_tag="KOU88_000071"
     CDS             complement(77767..78528)
                     /locus_tag="KOU88_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase"
                     /protein_id="HBK3210000.1"
                     /translation="MKNKIEISMNNFVKNYHKSNNITTKWQELLFAYASAEDDMFQKL
                     KSVVGTSHAMPKDFLENGKTIITYFIPFDESVNNSNIGGFECSEIWARAYIETNMLIS
                     NLNDFLCEELEKIGANSYAIPGSYNFDSEKLVSDWSQRHVAFIAGLGTFGLNNMLITE
                     KGCCGRIGSIITSLELEPTKRPENEYCLYKHNNSCKKCVNKCVKEALKEDGFNRNKCY
                     EMCMINEKKYTYIGGCDICGKCIVGVPCSVINPSR"
     gene            complement(78697..80760)
                     /gene="bclA3"
                     /locus_tag="KOU88_000072"
     CDS             complement(78697..80760)
                     /gene="bclA3"
                     /locus_tag="KOU88_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA3"
                     /protein_id="HBK3210001.1"
                     /translation="MLLIMSRNKYFGPFDDNDYNNGYDKYDDCNNGRDDYNSCDCHHC
                     CPPSCVGPTGPMGPRGRTGPTGPTGPTGPGVGATGPTGPTGPTGPTGNTGNTGATGLR
                     GPTGATGATGPTGATGAIGFGVTGPTGPTGATGATGADGVTGPTGPTGATGADGITGP
                     TGATGATGFGVTGPTGPTGATGVGVTGATGLIGPTGATGTPGATGPTGAIGATGIGIT
                     GPTGATGATGADGATGVTGPTGPTGATGADGVTGPTGATGATGIGITGPTGPTGATGI
                     GITGATGLIGPTGATGTPGATGPTGATGPTGVGVTGATGATGATGADGATGVTGPTGA
                     TGATGANGLVGPTGATGAAGTPGATGPTGATGPTGVGITGATGATGATGPTGADGATG
                     PTGATGNTGADGVAGPTGATGATGNTGADGATGPTGATGATGADGATGPTGATGATGV
                     AGATGATGPTGATGATGADGATGPTGATGATGADGATGPTGATGATGVTGATGPTGPT
                     GATGATGASAIIPFASGIPLSLTTIAGGLVGTPGFVGFGSSAPGLSIVGGVIDLTNAA
                     GTLTNFAFSMPRDGTITSISAYFSTTAALSLVGSTITITATLYQSTAPNNSFTAVPGA
                     TVTLAPPLTGILSVGSISSGIVTGLNIAATAQTRFLLVFTATASGLSLVNTVAGYASA
                     GIAIN"
     gene            complement(80827..81903)
                     /locus_tag="KOU88_000073"
     CDS             complement(80827..81903)
                     /locus_tag="KOU88_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3210002.1"
                     /translation="MITISLCMIVKNEEEVIGRCLECVKDIVDEIIIVDTGSTDSTKE
                     IVSKYTDMVYDFEWIDDFSAARNFSFSKASKDYTMWLDADDIILEADREKLLKIKESL
                     DTSIDIVMAKYNVSFDENGNPTLSYYRERLFKRSSNHKWVDPIHEVVPLFGEVFYSDI
                     AISHKKLHRQDPLRNLRIFEKMISEGKTLEPRHQFYYSRELYYNARYKEAIEGFTKFL
                     DSSRGWIEDCISACRDLATCYYLINDEKSALYSLFRSFEFDEPRAEICCDIGKHMFDR
                     QKYKEAIFWYKVALTRDKNDTNGGFKSNDCYGYIPSIQLSVCYDRLGESDKAIYYHEK
                     TKEIKPNDSAVLHNENYFSKFKNS"
     gene            complement(82215..82799)
                     /gene="clpP"
                     /locus_tag="KOU88_000074"
     CDS             complement(82215..82799)
                     /gene="clpP"
                     /locus_tag="KOU88_000074"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBK3210003.1"
                     /translation="MSLVPHVIEQTGQGERSYDIYSKLLKDRIIFIGEEINDAIASLV
                     VAQLLFLESEDPDSDIIIYINSPGGSATSGFAIYDTMNYVRCDVSTICIGMAASMSAF
                     LLAGGTHGKRCALPNSEIMIHQPMGGAKGQATDVKIAVDNILKIKERLDKILSENTGK
                     SIEDIRRDTDRDNFMTALEAKEYGLIDYIMNRNE"
     gene            complement(82796..83254)
                     /locus_tag="KOU88_000075"
     CDS             complement(82796..83254)
                     /locus_tag="KOU88_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210004.1"
                     /translation="MEIIDYIEENLTENLNLDKIAYIANYSKYHLHRMFTNVVGCTIH
                     QYIQRRRLTEAARQLIFTDKYIIDIAITVGYSTHQSFTLAFRNLYKESPQVYRNKDEF
                     YPIQQRFVLNLNHQIQSEKCISYANMNYKQRRDEINSYLNFNINCEVKVA"
     gene            complement(83477..84892)
                     /locus_tag="KOU88_000076"
     CDS             complement(83477..84892)
                     /locus_tag="KOU88_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK3210005.1"
                     /translation="MWITINRNSNISLSRQIYCEIKDMILDGSLKFEQKLPSSRTLSK
                     ELSVSRNTVLDAYNQLIAEGYLETRNGYGTIVAKGISGHKVDFKLNDTFRDEKDLHTN
                     KQKNYIDFRSGVPELKLFPRKELSKLYKQILYDLSDSDFRYGSTAGVWVLRVEISKYL
                     FRTRGIRCNPKNIMIVSGSTQGLSLISQLLYKSNKKVAVEDPIHKGLLKVISSIGYSV
                     VGIKVDDKGMNTNLIKSIKGISFVYTTPSHQYPLGGILPIQRRLELIKCATENDYYII
                     EDDYDSEFRYEGQPISSLYELSPNKVIYIGSFSKILSPAIRVGFMLLPDNILESYKTL
                     KMYSDVHTETILQHVLAEFIGNGGLEKYIFRMKKLYNRKRKYLIKVLNTEFKNEFKIK
                     GEAAGLHIVAHFYNVKFTESLIHKIFEAGIKVYPIQQYAIENILEYDHEIILGYAHLS
                     FDEIEKGVKILSKIIHMNQGT"
     gene            85007..85675
                     /locus_tag="KOU88_000077"
     CDS             85007..85675
                     /locus_tag="KOU88_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBK3210006.1"
                     /translation="MLEVSHKVKEIYPNIKFGVMVINITHSKPNKENFLVLKNSTIKN
                     IIEQHPEYNRKEKIKTEPVSSYIKYYKKFKKTYPVLLQLESILLKSKGIPDVGVTIES
                     MFLAELKNLLLTAGHDLDKMELPLKIELANGSEHFYGIGGKEHILTKDDLFLSDNIGI
                     LSSILNGPDNRTAITKDTKNIMYFVYGPDKISEKQIQDHLNDIKHYISSAFPDLKVNS
                     IDIF"
     gene            complement(85852..86370)
                     /locus_tag="KOU88_000078"
     CDS             complement(85852..86370)
                     /locus_tag="KOU88_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK3210007.1"
                     /translation="MNFVELAKKRYSCRNYQDRKVEKEKLEKVLDVARIAPTGGNRQP
                     QRLIVIQEKEGINKLSKAANIYDAPLAILVCGDKDKVWTRPFDGKQLTDIDTSIVTDH
                     MMLQATELGLASVWVCYFNPDIIREEFSLPDNLEPINILLMGYESKIPESPERHEKTR
                     VPLSEIVSYETL"
     gene            86522..86845
                     /locus_tag="KOU88_000079"
     CDS             86522..86845
                     /locus_tag="KOU88_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210008.1"
                     /translation="MKKCLDNYSCPIEATLALIGGKYKTLILWHLKDTILRFNELKKL
                     IPKATPKMLTQQLRELESDGLIIRVVYPVVPPKVEYSLSDFGKSIIPILDSMCDWGSD
                     YLENL"
     gene            complement(86850..87434)
                     /locus_tag="KOU88_000080"
     CDS             complement(86850..87434)
                     /locus_tag="KOU88_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBK3210009.1"
                     /translation="MKVLVFLAKGFETMEFSVFVDVMGWARNDYGHDIDVVTCGFKKQ
                     VMSTFNIQVLVDKTIEEVCVDDYDALAIPGGFEEFGFYDEAYDSSFLNLIREFNSKEK
                     IIASICVAALPVGKSCVLKNRKATTYHLKNGKRQRQLSEFDVNVVNEPIVVDKNIITS
                     YCPETAPHVAFKLLEMLTSKEQMDEVKLAMGFKL"
     gene            complement(87483..87938)
                     /locus_tag="KOU88_000081"
     CDS             complement(87483..87938)
                     /locus_tag="KOU88_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBK3210010.1"
                     /translation="MDEIDLKIINSLKKNSRASTSEISRQINLSVPAVSERIRKIEQS
                     NLIQKYTIQINREKTKYKLLAFIFINTDLSKSMKEFKKTILEYDTVLECHHISGEYDY
                     LIKVLAEDTSSLEEFISVTLKEIGGIQKANTTIVLSTIKEEFNTIKDIF"
     gene            88820..90358
                     /locus_tag="KOU88_000082"
     CDS             88820..90358
                     /locus_tag="KOU88_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK3210011.1"
                     /translation="MSLLKVTNLSQCFMDKSLYEKANFDLFKGEHIGVVGQNGTGKST
                     LIKILLGEVVPDSGEIKWQPNINIGHLDQYAEINRDTTISLYLHTAFEELYKIEKEMN
                     LLYQKSAISENEQYLIKASDYQEQLIASNFYSIDNEINKIANGLGLDSIGMNRVVGEL
                     SGGQRAKVILAKLLLSNHDVLLLDEPTNFLDKEHVEWLSNYLNTFNGAFIVVSHDFDF
                     LEKISTGILDIEFGMIKKYHGKYSEFLKQKSHLREDYIRRYQAQQKKIEKEETFIRKN
                     KAGVNSKIARGRQKQLDKIERIAPPSFTGKPNIQFSEIEISAQNALTITNLEVGYYYS
                     LLPKLNFSVDGGQKIVITGFNGIGKSTLLKTLVKDIPRISGDFQFSEQVKIGYYEQDL
                     KWENPDKTPLQIVADKYPKLNTKEIRRHLARCGVKEEHVSRSVSTLSGGEQSKVKLCC
                     MMLSPCNFLILDEPTNHFDAETKDALQNALKQFRGSIILVSHEEKFYKGWIDKVFNIE
                     KQLV"
     gene            complement(90630..91343)
                     /locus_tag="KOU88_000083"
     CDS             complement(90630..91343)
                     /locus_tag="KOU88_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210012.1"
                     /translation="MDTCFNKKILLVDDEKDIVDLIEEVLINDGFKNIIKAYNGLDAI
                     SLCKIACPDVVILDIMLPDIDGIEVCKKIREFSYCSILFLSSKNDDIDKILGLSSGGD
                     DYITKPFSPREIAFRVKAQLRRQQYQSIVPSDSEVIKIGDITIDIEGNRVYKDRNEIE
                     LTGREYHLLSYMAQNVNKIIGKERLYEQVWGVYSSICDNTIMVHIRHIREKIEDNPSN
                     PKILITVKGLGYKLVNRID"
     gene            complement(91791..93170)
                     /locus_tag="KOU88_000084"
     CDS             complement(91791..93170)
                     /locus_tag="KOU88_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3210013.1"
                     /translation="MSDVYYSENHEQDNLYEQDNLLAQRFNLFTLLKFAFPTIFMMIF
                     MGLYTIVDTIFVSRFINTNALSAINIVCPIINLIVGIGTMLATGGSAIVARKMGNGDI
                     EGANKAFSLIVLSGVVIGVIITGIGIVFMDYIIIWLGASEVLIKYCRSYLFIILVFAS
                     ANILQVLFQCLFVTAGKPQFGLWLVLGAGCANIILDYVFIVLLQMGISGAALATGVGY
                     LIPTVSGMVFFSKNKGLLKFCIPRLDKRILFEACFNGSSEMVSQLSTAVTTFLFNAMM
                     MKLIGEDGVAAITIIIYSQFLLTSLYIGFSMGVAPIISYNYGSENNTQLNHVFKICIL
                     FISVASLLVFIFSISCSPIIVEIFSQRGSRVYEIARSGFYIFSFSFIFCGYNIFTSSM
                     FTALSNGKVSAILSFLRTFGFITIGLLILPNILNINGIWLAVPSAEILTLFLTIFCIC
                     KYKNRYKYM"
     gene            complement(93455..94249)
                     /locus_tag="KOU88_000085"
     CDS             complement(93455..94249)
                     /locus_tag="KOU88_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBK3210014.1"
                     /translation="MMKKNLKIIFMLLKMKLSKMMVFRFDFFGAFFVDSSLFILQLLM
                     FNSIYSHVDSIGGWKQGEMLIFIGTFSLINAINMTIFFFGIYDIPRKIQEGELDYYIT
                     KPLDPLFRLTFENINIGSSPLILASILIVLYGISELNSEITLAMIIIYIFMVLLMTLL
                     FYDVCIILRTVSFFVISSSAIMRLEDNLLPMNMKIPGVIYEGVFKVLFYLILPYGIMS
                     TIPTQILAGTITINGLIYSILIVFLFTLFMWRFWKLGMRHYKSASS"
     gene            complement(94246..95109)
                     /locus_tag="KOU88_000086"
     CDS             complement(94246..95109)
                     /locus_tag="KOU88_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HBK3210015.1"
                     /translation="MSIMSNYNEASSNYSMFYKFKQSIRRYYEVAKINFKVQLIWRFD
                     VVVNMVFTIVKILFAYILWKAIFGENKIVSGFTFNSMLSYYIISSFLAGIDMSKSTSE
                     EICNRVKLGTFSKYMIIPINVQNYFIAKNFGMTCFYFVFNMISAFVWIFIFKIDFAFT
                     SNPVQILISILMIFLGFIFMMKLHFFIGILSFKFLEISFFRMIIENIVEFITGTMIPL
                     VLLPETIVTVMKVFPFYYTTYLPSMLLIGRNSNEAIQGLIILALWVLFFSVVNKVMYK
                     RMRTLFDGVGI"
     gene            complement(95087..96082)
                     /locus_tag="KOU88_000087"
     CDS             complement(95087..96082)
                     /locus_tag="KOU88_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3210016.1"
                     /translation="MSIIELNELTKSYRRFEKKAGFMGSVKSLFNRKYTEKTAISSFD
                     LKIEEGEFVGLIGQNGAGKTTLIKMLTGIIAPSSGEISVMGYYPNKLENNFKKQYAVV
                     MGQKSQLFFELTPADTFLLFKELYDISNEEYKKNLDYFIELFEVSDYLNVQVRTLSLG
                     ERMKMELIVALLHNPKILFLDEPTIGLDAIAQKQIRYFLKEVNETKGTTIILTSHYME
                     DIKSLCSRSIVVENSRKIYDGSTEKLFNHFQKYKKITVSFSNETNIVFPKDCKVVEQT
                     NHKTSVIVPKERGNETIKWIFDKYDVKDVMIEEEDIGSIVERIYKKGSDEYYEQL"
     gene            96786..97742
                     /locus_tag="KOU88_000088"
     CDS             96786..97742
                     /locus_tag="KOU88_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBK3210017.1"
                     /translation="MENNTIQKQLRDLSKKIWHIYILNPEEENLKFIISLLDDNLALI
                     GTGKHEFYETLEEFIIGLEKDQTESEQIDFEIIDEWYSCTKVTDEAFIVYGTLWVIEK
                     DYLEKDIYVEMDTRFTMVYRVTDDMIKLIHVHHSIPNFDQMKDEYYPKTITEKAQEAL
                     AMANEFKLKSEKDLMTGLYNRHFFEVHIKEMLKTVSHGYFYIFDLDNFKQVNDIFGHV
                     RGDEILIQFSNILTKVFVNDAIIGRLGGDEFAVFEYSNQSKENVENKAKKVLELCLES
                     NSCSIGISKLENNSDTFQSLYKQSDYALYYSKRNNKGNFSWF"
     gene            complement(98142..99032)
                     /locus_tag="KOU88_000089"
     CDS             complement(98142..99032)
                     /locus_tag="KOU88_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210018.1"
                     /translation="MKKNILTTMITMIIILMMSMTVMAEPYQEDETSSLEKQSANERN
                     QTNIGTMDGRVQTNAISKGANYDPKYPLKGMLTQLGLNTTGKEGWDLLYGGNPNGVEL
                     RADGKYYYINKGMEGLGFYAAALSGVSYQRIGFGKLDPIEVIADGNWISYKQAQDTLT
                     VIRNFLNSFDWRNASEMERANRAAKLVTEAKYADSKYCNIVYGNLVDKRGVCGSFASS
                     FHLLTRLMGMDSLSILNPSLNHAWNYIQIDGKWYRFDGSEISAFGGSLDFDYRKLKDA
                     TREMTTYYDAKALSILGFNQ"
     gene            complement(99210..99908)
                     /locus_tag="KOU88_000090"
     CDS             complement(99210..99908)
                     /locus_tag="KOU88_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210019.1"
                     /translation="MKISSQYRSQYSFRYESNINNTRINESMVKKNETVGKDTYLSNI
                     MKQKQELNDRIRDLKYRQEVYTKKINDAIKNLCKSEIRETTNNFSNIEIGIKNSIIED
                     KNKSTMLDENSTYLNTNDEKESLITKESNEKIEEEILNDEKLEELEQKKDYKEDSNKK
                     EKVSEDLSLVGKTREELENMLKNFINLTQEEIMKLESRIEKLDKDAEEYKQNSKTNIF
                     DKTDEQKKHINVLI"
     gene            complement(100444..101511)
                     /gene="rsgA"
                     /locus_tag="KOU88_000091"
     CDS             complement(100444..101511)
                     /gene="rsgA"
                     /locus_tag="KOU88_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBK3210020.1"
                     /translation="MNGMKQINLQDYGLNRNFITQSMEYHDLYLARIISQEKNFYQAV
                     CVNGVLFAEVSGKLRFEATIQSDFPTVGDFVMLDRCNNKNGNAIIHHVLHRKSLFVRK
                     AAGKVNEEQVVAANIDIVFLCMSLNKDFNIHRLERYLSLTWESGAIPVVVLTKSDLCD
                     NVYRKLQVVNSIALGVDVVVTSSIEPDGYKQISKYIKPGCTVALLGSSGVGKSSLINC
                     LLGGEFLNTKEIRIDDDKGRHATTRRELFLISGGGIVIDTPGMRELGMWDVSEGLDKS
                     FADIEAYFGKCHFRNCTHTSEPGCAIWKAIAHQELSPKRWESYRRLKTEAVFADNKSE
                     YLAKKEKKFKNISKINKKIRR"
     gene            complement(101508..101909)
                     /locus_tag="KOU88_000092"
     CDS             complement(101508..101909)
                     /locus_tag="KOU88_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNHCP domain-containing protein"
                     /protein_id="HBK3210021.1"
                     /translation="MNYKNRKRAYYQENSCMDNFICKNCGCLVVPEGAGTQHRNHCPH
                     CLHSLHVDIIPGDRAADCDANMEPIGVWVRKNGEWAIIHRCTRCGHLSSNRIAADDNS
                     VKLMSIALKPLAQPPFPLERIIEKLEKEETE"
     regulatory      102705..102801
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            102855..103031
                     /locus_tag="KOU88_000093"
     CDS             102855..103031
                     /locus_tag="KOU88_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210022.1"
                     /translation="MFRDKMDRCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            103441..104079
                     /locus_tag="KOU88_000094"
     CDS             103441..104079
                     /locus_tag="KOU88_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210023.1"
                     /translation="MSNQRKDFDITNDMFQESIPITTKIILEDMPSNDELNHVFSKGC
                     ERKMKKRKIVLITLLLIGVLLLGSILYNLFLGKTANISMLKESWNFDIPIPNKEIEVF
                     DTQDSINGDGQNYFIQGFSEKNFKKVFNLKGGIVVSKDNINEIEKYIDKFKRDSVNIN
                     KSNKNKIEEDFKKYKLEVKKDDKYIYKRNYENYVVLIIKKDEQKLYSLIWNQ"
     gene            complement(104573..106333)
                     /locus_tag="KOU88_000095"
     CDS             complement(104573..106333)
                     /locus_tag="KOU88_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK3210024.1"
                     /translation="MQEVEVIKAKNVLSRQARGKAIERLRVAAYCRVSTDSEDQLNSY
                     KSQVQYYTDMIKKNKEWVLADIYADEAITGTQVTKREDFQRMINDCMNGEIDMVFTKS
                     ISRFARNTLDTLKYVRMLKERNIAVYFEDEKINTLTMDGELLLVVLSSVAQQEVENIS
                     ANVKKGLKMKMKRGELVGFQGCIGYDYHPEDKTITVNQEEAEIVRYIFNRYVDGAGGS
                     VIGQELESLGYKTKYGSSTWAPSTVIGIIKNEKYKGDILLGKTFTVDPISKRRLENMG
                     EEDKFYMKDHHEPIISEEVFEKAQEILNRRNKNRTTVGSGKREKYSRKYAFSCMLECG
                     FCGGTLTRRNWHSGSQYSKVIWQCVTATKKGKKFCKHSKGIPETAIEEAFVESYRLLC
                     DDNKDVLEEFLQRMDDTLSSSVVSKQLAKAEKEIDALEKKKSKLVDMRLEEIIDKETY
                     ESKYADLVSKQEQLVEERQKLQETSDNEKDIKKRLKEFKKTLEQNEVLDKFDRYVFES
                     IVEKVIVGGLDENGNVDPAQLTFVYKTGLKNSVDGAKFKPQRKNARGRHRTNELCSHD
                     SNEVDKMCSDSSNDTCGNCS"
     gene            complement(106396..106539)
                     /locus_tag="KOU88_000096"
     CDS             complement(106396..106539)
                     /locus_tag="KOU88_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210025.1"
                     /translation="MNNIIRYSMQIAMLKQLLARKLISEKEYTLVKQRLMKDYKVLSD
                     ITA"
     gene            complement(106858..107097)
                     /locus_tag="KOU88_000097"
     CDS             complement(106858..107097)
                     /locus_tag="KOU88_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3210026.1"
                     /translation="MMKSTKKCPSFSTISSAADGNEVAIEKILNHYDAYISKASLRPF
                     YDEHGNMYIVLDMELKGRIRAALIKVILGFEVKVK"
     gene            complement(107102..107518)
                     /locus_tag="KOU88_000098"
     CDS             complement(107102..107518)
                     /locus_tag="KOU88_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002592281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3210027.1"
                     /translation="MKPSSFEGAIRLQFDCLARKVVGRTVKNYDRELGRRARRETPFC
                     DLSEMELNQIGVMDEYCVEFTSFDVFGSEVHIYDERLCEAIKELTESRRNILLMSYFL
                     EMTDAEIAEVMEMERFSVCRNRLHTLKLIKDMYEEE"
     gene            complement(107515..107814)
                     /locus_tag="KOU88_000099"
     CDS             complement(107515..107814)
                     /locus_tag="KOU88_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210028.1"
                     /translation="MKHLHIQQLSTIGSSLKKHLNSTEHNAPICGFLQHITGIICLAQ
                     DQYVCIALVLFYCIKLFQKIFVVGYQIPPFTVSVSAKRGRSLFALATFAGKGVRL"
     gene            complement(108865..109032)
                     /locus_tag="KOU88_000100"
     CDS             complement(108865..109032)
                     /locus_tag="KOU88_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002587909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210029.1"
                     /translation="MNWKELWMTLFGTTEWLGLNIGFWVAMAVVLLIVIVMNVVFWSM
                     KPKKDTKESYK"
     gene            complement(109045..111810)
                     /gene="mgtA"
                     /locus_tag="KOU88_000101"
     CDS             complement(109045..111810)
                     /gene="mgtA"
                     /locus_tag="KOU88_000101"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002571344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBK3210030.1"
                     /translation="MNKKENRMAIRQTVEKAVIRDEQNRRIQFAATNPIKEVLKKLHT
                     TLRGLEVDEVSVSRAKYGTNKVTHEKKKSLAKRLVGAFINPFTAILFCLALVSTITDM
                     IFPYFSLFGSVPEDFDSLTVVIILTMVFISGTLRFVQESRSGNAAEKLLAMITTTCTV
                     TRRNYEKKELPMDDLVVGDIVHLSAGDMIPADVRILDAKDLFVSQASLTGESEPIEKT
                     PNVSAQKESVTDYTNIAFMGSNVISGSATAVVVCVGDHTLFGSMASAVAGEAVETSFT
                     KGVNAVSWVLIRFMLIMVPLVFFVNGITKGDWLAAFLFGVSIAVGLTPEMLPMIVTTC
                     LAKGAVSMSKKQTIVKNLNSIQNFGAIDILCTDKTGTLTQDKVVLEYHLNVNGEDDTR
                     VLRHAYLNSYFQTGYKNLMDLAIIHKTEEEEAADSRLIDLSENYVKVDEIPFDFTRRR
                     LTTVVQDNKGKTQMVTKGAVEEMLSICAFAECNGGVQPLTDDVRYRILETVDNLNDKG
                     FRVLAIAQKSNPSPIGAFGVKDECDMVLIGYLAFLDPPKESTADAIKALKDHGVITKI
                     LTGDNDKVTRTICKQVGLEVRNMLLGSDLEQMGDAELARVAESTDVFAKLTPDQKARV
                     VSVLRENGHTVGFMGDGINDAAAMKAADIGISVDTAVDVAKESADIILLEKDLMVLEQ
                     GIIEGRKTYANMIKYIKMTASSNFGNMFSVLAASALLPFLPMMSVHLIFLNLIYDLSC
                     TAIPWDNVDEEFITKPRKWDASSVGSFMIWIGPTSSIFDFTTYIFMYFVFCPLFVSNG
                     VLFNDLPAHFSGAELAMLQAQYIGMFQAGWFVESMWSQTLVIHMIRTPKLPFVQSRAS
                     APVTLLTMTGIIVLTIIPFTVFGTMLGFVALPAAYFAYLIPCILLYMTLATSLKKAYV
                     RHFGELL"
     gene            complement(111976..112287)
                     /locus_tag="KOU88_000102"
     CDS             complement(111976..112287)
                     /locus_tag="KOU88_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBK3210031.1"
                     /translation="MDFTCIFFGILFTLAGFWLAFGKGYRHLSLWKNMPQEEKDKINI
                     VPLCRNVGEMIALNGIIFLMKGFLPGFSNHWFVFAIIAWLIVAGFDVWYIEKSVRYRN
                     Q"
     gene            complement(112534..113211)
                     /locus_tag="KOU88_000103"
     CDS             complement(112534..113211)
                     /locus_tag="KOU88_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBK3210032.1"
                     /translation="MFYTDFILRIALSLTLGFLIGLERQLTGHPAGIRINVLICMGTS
                     FFTLFPMLYGSDQVFRVGSSIISGVGFLCSGVIFKDRGTVRGMNTAATLWCTAAIGIL
                     ASTGMYAMAITAATILIGSNLILRPFARKFHPITSSDESEKQYRISVTCQEKAEQDIR
                     LLLINSNSCKTLFLNNLESGDVVGDKVEIVAEYCSVGKSKNNILEGIVGQVLVIPEVI
                     SAGWEVL"
     gene            complement(113349..113852)
                     /locus_tag="KOU88_000104"
     CDS             complement(113349..113852)
                     /locus_tag="KOU88_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006566797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK3210033.1"
                     /translation="MKKNISYIPMDSALEIWLLEKLLRDPPDSDCAKDLLSGIQEMIR
                     GEVSSLLLGASEESDWPVGTLSDRILAGDLEIYPRGRKVLIKGSEVNLTPKEFDILYF
                     LVQNKGEVFTKEQIYRAVWEEDYILDNSNIMAFIRKLRKKIEPAPDCPTYILTIWGIG
                     YKFNDQI"
     gene            complement(113868..116531)
                     /gene="mgtA"
                     /locus_tag="KOU88_000105"
     CDS             complement(113868..116531)
                     /gene="mgtA"
                     /locus_tag="KOU88_000105"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBK3210034.1"
                     /translation="MSKATLFDSRIKKYAYCRTSEIYRDIGSSPDGLSIEQIGSMREK
                     YGANSFNGRKNDTTMQRLRRAFINPFHVILFVLGIVSLVTDVFVASNFARNATTAIII
                     FSMIVISGVIRLIQELRAKSAAAQLDRLVHESVTVRRDGKLIEIPGEELVVGDIVLFS
                     AGDRVPADIRLTKITDLFISQAAITGESAIIEKSCRKLSYGEQDTLTQLENLAFMATT
                     VISGKGEGIVLAVGKDTLYGGFTKPDSDDKNSFKKGADSIAWVMIRFMAILVPIVFIL
                     LGITDGKWMESFAFALSVAVGLMPEMLPMVITACLAKGSLAMSKKQTIIKDINAMQSF
                     GSMDVLCMDKTGTLTNESILLEYYMDIFGNENAEVLDLAYLNSCYHSGVCNTIDNAIL
                     ACNTMPGREAHYANLLTKFQKADEIPFDYARKFVSTLVQDSNGNSQLIMKGDIEHIFS
                     RCNHVEYRGKLLPMGQDARHSVSSVVGEMLQDGMKVIAVARKNVGAQKKITPDDEWGM
                     TLVGYLSFFDAPKQTAKESVTALKRLKVIPKILTGDQAAIAVSVCRRVGISTERILTG
                     TQLDEMTDCELKKAVEHTHVFAELTPGHKVRLVSAMQDNGHSVGFLGDGVNDIPALNE
                     ANVGISVDTAVDAAKDAADVVLLQKDLNVLEQGVMEGRKTFTNMLKYIKITASSNFGN
                     IFSIICASAFLPFLPMTSIQILLLNLLYDTLCIVLPWDNVDEEEMLSPRDWSGKTLRQ
                     FMLSFGPISSLFDIVTFLFLYYFLCPMLCGGATYLQLTDPSLQLQYVALFQTGWFLES
                     MWTQVLILHFLRTSKIPFFQSRASAPVISITLVGIIAFTSLTFVGGASLFGLTKLPLW
                     YFVFLLLVVSLYMLLNSVAKYFYKKKYQELI"
     gene            complement(116624..116833)
                     /locus_tag="KOU88_000106"
     CDS             complement(116624..116833)
                     /locus_tag="KOU88_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210035.1"
                     /translation="MVKVKTKKKFVSTHMCQGEMPIYVRERYEKMLAVSIRAPNLEGM
                     VENFDKDLSHPNETDLIELKNAISK"
     gene            116783..117119
                     /locus_tag="KOU88_000107"
                     /pseudo
     CDS             116783..117119
                     /locus_tag="KOU88_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729345.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(117318..118220)
                     /locus_tag="KOU88_000108"
     CDS             complement(117318..118220)
                     /locus_tag="KOU88_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210036.1"
                     /translation="MFKKNKKSTENVKEKKVRTVKVGTHKKTVIALWVVLIESVSFGV
                     YKNFTAIDQHTTHEKEVIELRLQDTNGIENFVKNFAKSYYTWSNSKEAIEARTQAING
                     YLTKELQDLNVDTIRTDIPTSSTITDVIVWSIEQSGTDTFSATYEVDQQIEEGEQTTA
                     VKATYTVKVHVDDDGNMVIIQNPTLAPAIEKSDYEPKTPEADASVDADTINDATAFLE
                     TFFKLYPTATEKELAYYVSGNVLESIGRDYLYSELVNPIFTVDGDNVKVKVAVKFIDN
                     QTKATQVSQFELVLHKDSNWKIIG"
     gene            complement(118236..119243)
                     /locus_tag="KOU88_000109"
     CDS             complement(118236..119243)
                     /locus_tag="KOU88_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK3210037.1"
                     /translation="MKLKHIAIIGSLFPILFSLVLFLGVLISADSDDENSNFSSGITG
                     MNLSAEVLKHQPMVEKYARENGISEYVHVLLAIIQVESGGTAEDVMQSSESLGLLPNS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ESFAREKSVGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVAHFDNATAQAIM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNKMYHAGDPIGYADLSSSYWQQHLIGAGRVK
                     E"
     gene            complement(119246..121450)
                     /locus_tag="KOU88_000110"
     CDS             complement(119246..121450)
                     /locus_tag="KOU88_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3210038.1"
                     /translation="MKERIQSAFTKRKILHFLKMALFVVALSLILLSLLGTVAHATGL
                     VDDTINAENLYSKYPLSNYQLDFFVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTENGFSSTGFYVGFLLLIIL
                     VVGMYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVQQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIITVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRP
                     YLFMRHRARRMEHRIARAVSAGGISGGVAGAVAGSAVAGKRSERKNTASKENRGNTTS
                     SMGQRAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKR
                     GMVQEQQSRQTGRLEKQEQHKKSIAVKRMELQKAQEARHRKTDGSATTGATRPHERPA
                     TASTVPKTSVEKMQEIKRPATAPTSKASEPVKTNVIKERPLSSGASDMKATQSAQPVH
                     RQNVEKVVSQETRQNYTKDRRTKVQQTQTVQKNQQTTEKNRNIVTKKGQKKK"
     gene            complement(121450..123900)
                     /locus_tag="KOU88_000111"
     CDS             complement(121450..123900)
                     /locus_tag="KOU88_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210039.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLREVAVQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGIAYEDYEYQLPKKKLKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNVIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGENTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            complement(123878..124276)
                     /locus_tag="KOU88_000112"
     CDS             complement(123878..124276)
                     /locus_tag="KOU88_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210040.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLHKQILNETITAVRSVNYVPDKIY"
     gene            complement(124394..124897)
                     /locus_tag="KOU88_000113"
     CDS             complement(124394..124897)
                     /locus_tag="KOU88_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK3210041.1"
                     /translation="MIDDMAVYIANLGRYNEGYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAVHDTDNFPIDIGEYVSIEELNEMYEMIEELPDYIVECLDEFISHYGTLEEVVEH
                     KDDIYFYPDCETMTDVAYYYIDELNALGDIPANLQNYIDYEAYGRDLDMGGRFIETSR
                     GICEIPY"
     gene            complement(124915..125418)
                     /locus_tag="KOU88_000114"
     CDS             complement(124915..125418)
                     /locus_tag="KOU88_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK3210042.1"
                     /translation="MQETRVLVETRGTTGEETISYWFDLPIDVAEFEEKLGVGAESGD
                     YRIIEKVLPYADEVHEHTSVYQLNELDFMYRQLSSDMQEEYVSLLTVYENLEALYICR
                     NVITVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLQEHGKFLVTEH
                     GIFELPE"
     gene            complement(125337..125633)
                     /locus_tag="KOU88_000115"
     CDS             complement(125337..125633)
                     /locus_tag="KOU88_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210043.1"
                     /translation="MNDIFKDMQAKVGCEYISDLPSYKRKVWHEMKRLNPADYEEKQL
                     EDFSKYVFGMSYQTIKDVRKQQKGREEQCRKQGCWWKREEQLAKKQYHTGLTCR"
     gene            complement(125716..126357)
                     /locus_tag="KOU88_000116"
     CDS             complement(125716..126357)
                     /locus_tag="KOU88_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloramphenicol acetyltransferase CAT"
                     /protein_id="HBK3210044.1"
                     /translation="MEYKYTKIDLEKWNRGKLFQSYIDDMRIVMSLTVDIDVTNLIEF
                     SKSHDLKFYPAMIWVVSKVVNEHDEFKYSWDNKGNLIKWDYISPSYAEFHKEDENFTK
                     MVTDFSDSIFEFHERFMLDREKHKMERAFVANQPLNFFDVSCLPWVKYNHFDVHVFDE
                     GKFLAPVITWGKYELERERYIMPLTMNIHHAVADGFHLSRFFNEVQELINSIS"
     gene            complement(126565..126786)
                     /locus_tag="KOU88_000117"
     CDS             complement(126565..126786)
                     /locus_tag="KOU88_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210045.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(126787..126921)
                     /locus_tag="KOU88_000118"
     CDS             complement(126787..126921)
                     /locus_tag="KOU88_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBK3210046.1"
                     /translation="MWELVKDFLLVSMGMGIGVVLMCILSIGKEADYEMKQLEESEDN
                     "
     gene            complement(126934..128130)
                     /locus_tag="KOU88_000119"
     CDS             complement(126934..128130)
                     /locus_tag="KOU88_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBK3210047.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASGITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LVDGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKSRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLNEADIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNDRWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKKIDKGNGTDYMETIEKQATLSEKHEMIIKQQTTPA
                     KDLVES"
     gene            complement(128314..129708)
                     /locus_tag="KOU88_000120"
     CDS             complement(128314..129708)
                     /locus_tag="KOU88_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210048.1"
                     /translation="MRKIWNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNIKQLM
                     RTDWEHFSLLEKGLTLSPYNLITILIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNSFYEGMVQRSEEMKQHSNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLKTIGSLAQARQ
                     DGTATCEAKGDGTD"
     gene            complement(129775..130389)
                     /locus_tag="KOU88_000121"
     CDS             complement(129775..130389)
                     /locus_tag="KOU88_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210049.1"
                     /translation="MSEKLLDLLKIFLEKYLVPTVIAIVFSFIAYYVTPTDNKLLVKF
                     TIWGYAVFLFCVWFLIIELVIWLVQKIQYHNYSKGVEQRNKQRQAEEWQQSLEFLWTD
                     VDNLSSSDYKLLLRFIKNENQPYCSSGTPMGHCLLNSDWVHKTVSKPAKRVLIKSNQR
                     TSSKAIPIPVYETISETYQYILREDIYQMLKYSYEKYGKISHFK"
     gene            complement(130480..130863)
                     /locus_tag="KOU88_000122"
     CDS             complement(130480..130863)
                     /locus_tag="KOU88_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK3210050.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNAGNPQNHTPQGQTKK"
     gene            complement(130879..131205)
                     /locus_tag="KOU88_000123"
     CDS             complement(130879..131205)
                     /locus_tag="KOU88_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK3210051.1"
                     /translation="MEMKYVVPDMTQSFGTLEFAGESEPVFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            complement(131444..134488)
                     /locus_tag="KOU88_000124"
     CDS             complement(131444..134488)
                     /locus_tag="KOU88_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBK3210052.1"
                     /translation="MKKMLKRLCTGFLALATIVTALPTTPVHAESKQYWTESKERVGI
                     VEKVMNDGSIGSTFNEGMMKVEGETAYCIDINTDFKNGYKTRTDASSRMSADQISDVA
                     LSLEYVKQYGEAHKELNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITDGNG
                     NYSISGATYGVFSDKDCTKQLATLTTDENGNTNVVEVKAGTVYIKELSAPAGYKVDKT
                     VYPLTIKAGETATLKVSDTPKVTDTLIELFKIDMETQKDNPQGNASLAGAKFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSDETTHYITKLANAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPKGYLLDGAYMQAGDKSEQIKGVYVTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNAVLVEGKLYKKNEVVKTIR
                     TDIEGVASTSADLLPYGNFRIVESEAPDGYLTDGAKPIDFAITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSADWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEEMCCDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFVADEEEMKVEISYTFNASALGGKNPVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LKGLEVGTKYKLVGWQMLKAENAELLINGKRVESDYTFTADSETMKVEVAFTFDATSL
                     DGKQLVTFEELYDLSNPDKPKKVTEHKDIEDEGQTITFKEKPEEPEKPETPQTPEKPN
                     RPSDSPKTGDSTNVMAFIVMLFASAGGLAGTYLYKRRKMKKS"
     gene            complement(134733..136097)
                     /gene="rlmD"
                     /locus_tag="KOU88_000125"
     CDS             complement(134733..136097)
                     /gene="rlmD"
                     /locus_tag="KOU88_000125"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBK3210053.1"
                     /translation="MLSKNEMYIVDIVDIGQGGVGVGKYNGITVFVEGGLIQDKVKVR
                     INKVKKNYAVGDIVEIIEKSPFRVKRVCSENLRDCGGCQIQDLDYNKQLEMKTNEVKQ
                     VLSRIGKLEDVEVHDTIGMDNPYRYRNKAQFPIQKNNGIPIIGFYKKKTHDVISTEKC
                     VIQHEINDKIVKIIKTYIRAYKVSIYDEKTHTGLIRHLVTKIGFTTKEVMVVLVANGN
                     KLPYLKELASVLKENIPGFKTLVVNVNQKDTNAILGRENIVIYGDGKINDYIGDLVFE
                     ISPLSFFQVNPVQTKVLYDKALEYANLNDTDTVFDIYCGIGTISLFLAQKAKKVYGIE
                     IIDDAIKDAKINAKLNNIHNAEFYVGKAEEIVPKMYREGKTANVVVVDPPRKGCDEKV
                     LETIVSMNPERIVYVSCNPSTLARDLDYLNVHGFKCVEAQPVDMFPHSTHVETCVLLQ
                     RRTM"
     gene            complement(136272..138032)
                     /gene="pyk"
                     /locus_tag="KOU88_000126"
     CDS             complement(136272..138032)
                     /gene="pyk"
                     /locus_tag="KOU88_000126"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBK3210054.1"
                     /translation="MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSH
                     EEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGNFEDPEVFLEEGQKFTITMKDIM
                     GTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV
                     NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQ
                     IISKIENQEGVENLDEILKVSDGIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPV
                     VTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAGKYPVEAVKMMATIA
                     KRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSK
                     FRPKSPIIATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGE
                     LVVITAGVPVGVSGTTNLIKVHVISEEIVQGIGVGTQTVEGKVRIIKNGNACVDFNEG
                     DILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSATDITNLVKDG
                     EVVTVDASRGVVYRGSTRVL"
     gene            complement(138084..139043)
                     /gene="pfkA"
                     /locus_tag="KOU88_000127"
     CDS             complement(138084..139043)
                     /gene="pfkA"
                     /locus_tag="KOU88_000127"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBK3210055.1"
                     /translation="MKTIGLLTSGGDAPGMNAAIRAVVRSAIYYGCKVYGINRGYKGL
                     LEEDLTEMNLSSVGDIIHRGGTILKSSRCEEFKTEEGRLKAVKILKKYKIDCLVVIGG
                     DGSFAGAQKLSDLGFPAIGIPGTIDNDLAYTDYTIGFDTAMNTIIDAIGKIRDTSSSH
                     ERVNIVEVMGRHCGDLALYAGLAGGAETIIVPEVEITVDEVALRLKTTQKRGKRHSII
                     VLAEGVGSASDLEKELKKESGADLRVTVLGHVQRGGSPTVSDRILASRLGVRAVELLL
                     DGKSARVVGIKENKIIDLEISEALAQKKVFDKEAYEMAKILSI"
     gene            complement(139252..142821)
                     /locus_tag="KOU88_000128"
     CDS             complement(139252..142821)
                     /locus_tag="KOU88_000128"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBK3210056.1"
                     /translation="MNKDFAHLHVHTEYSLLDGFSRVKKLIKRAKELNMNSIAITDHG
                     CMFGVIDFYKTAIKEGIKPIIGCEVYTAARGLRDKDPNYDKYQGHLVLLAKNMEGYKN
                     LIKIVSTSYVEGFYYKPRVDMEELKKHNKGIIALSACLAGDVARALMNRNYEKAKQFA
                     LDYRDIFGEENFFLEIQDHNLPEQKEVNSGLVKLSKETGIPLVATNDVHYVNKEDSKI
                     HDVLMCIQMGKTLNDPNRMRFGSDEFYLKSREEMEELFPYALEAIDNTVKIADMCNVE
                     FDFNTIHLPKYDVPEGYTPETYLRELCFNGLKERYDNPSNEILERLNYELDVIEKMGY
                     VEYFLIVWDFINFSKENNIIVGPGRGSAAGSIVAYTLKITDIDPIKYSLLFERFLNPE
                     RISMPDIDIDFCYERREEVIDYVKRKYGDDHVAQIITFGTMGAKAAIRDVGRVLDIGY
                     NKVDKVAKEIPFALGMTIDKALDTNPNLKELYDQDPETKEIINISKQIEGMLRHASTH
                     AAGVVISKNPVDEYVPLYKHQDAITTQFTMTTLEELGLLKMDFLGLRTLTVIRDTLDL
                     IEKNRVIKNYTEKIDFSKMDYDDPKVYEMLSSGNTLGVFQLESAGMRSFMKQLKPDNF
                     EDIVAGISLFRPGPMDSIPAYIKNKSNPKDVTYLHEKLKPIMEVTYGCLVYQEQVMQV
                     VRDLGGYSYGRSDLVRRAMSKKKMDVMEEERQYFIHGKFDEDGNIEIAGCIRNGVEEE
                     IANKIFDDMIDFARYAFNKSHAAAYGVLAYETAYLKTYYPVEFMAALITSVMGNTDKV
                     VEYIRECKVLEIDVLPPDINKSFSKFSVEGDNIRFGLAAVKNVGVNIINNIIAERESN
                     GLFVDLVDLVKRLDQKDTNKRVIESLIKCGAFDNISENRASLMAGYESLLESVSMDRK
                     KNVQGQISLFDAFGDSEEDSDFQQIYSLPKRQEYEERERLNLEKEVLGMYVSGHPLSQ
                     FEKELQEKTSMDNGKLNSLKEEEESYLQMNETDVIMGGMIVTKTIKTTKRNEIMAFIE
                     LEDLYGAIEIIVFPQLLQKYNVILNEDNIIYVKGTLSIKEGENAKLIAREIKDINDDT
                     DFADRNYNSGRTRNVENIKPESGKKLYLKIDSMSDTDTTNNIVEIAKQYPGNDSIYLY
                     PMDENINGKRKAYKMTGALTCICDEFINNLEELLPKDNIKVKA"
     gene            complement(142978..143925)
                     /gene="whiA"
                     /locus_tag="KOU88_000129"
     CDS             complement(142978..143925)
                     /gene="whiA"
                     /locus_tag="KOU88_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBK3210057.1"
                     /translation="MSFSTETKNELARVISGNECCNIAELSALVKSGGSIQIVGYKKL
                     NLKITTELNSIARKVFKLLKKNFNINTTISVNKNQMLKRNNSYVLMVTSEMGSEMLLK
                     KLGILEDKEGFFTINKISENLIKHEGCKRAFIRGAFLGGGSISDPEKNYHMEFVTNNE
                     EFADSLKELINSLGFNSKIVARKNNHVVYIKESEQISDLLSIIGGHHALLSLQNTKIV
                     KEMRNNVNRIVNCETANLSKTVNAAVRQVENIKLIQETIGISSLPENLQEIAKIRIEY
                     EDMTLKELGEMLEPPIGKSGVNHRLRKIEEIATDLKKKS"
     gene            complement(143942..144367)
                     /locus_tag="KOU88_000130"
     CDS             complement(143942..144367)
                     /locus_tag="KOU88_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK3210058.1"
                     /translation="MREEVSAGGVVLFGNTILLLRKFNGDWVLPKGKVEEGENNQEAA
                     LREVSEETGVKADILKYLGEIHYTFKENWDENRAVHKTVFWYLMQAKNMDTIPQKEEG
                     FIDAKFIHLDRVVDLARYDDEKEIIKVALQEIKKRLKKN"
     gene            complement(144436..145542)
                     /locus_tag="KOU88_000131"
     CDS             complement(144436..145542)
                     /locus_tag="KOU88_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBK3210059.1"
                     /translation="MAKLLIIVGILGWIALIVSLFIYKKAKNEKVKLFQRSIVENREP
                     NVVVIGGGTGQSVFLRGLKHTTQNITAIVTVADDGGGSGVLREDLGMLPPGDIRNCLL
                     ALANIEPTMNEVMQYRFTEGLLKGQSFGNLFLAAMNGLYGNFEKAVYKLSEIFAITGR
                     VLPVTLEDVNLVAKLKNGNIINGESSIPEESKIQKSSIDKIFLNPKDVKPLKDVIASI
                     YDADIIIMGPGSLYTSIIPNLLVEGIVDAIKSSVAPKVYIANIMTQPGETEGYNVLEH
                     VNAIVEHTDENLIDYVIANNEILPEEMLDLYKQDGAEQVLLDKKQKDKLKEMGIKTVE
                     KNLIEIKNNYIRHDAKYISNIVIELALNHNYNKS"
     gene            complement(145554..146411)
                     /gene="rapZ"
                     /locus_tag="KOU88_000132"
     CDS             complement(145554..146411)
                     /gene="rapZ"
                     /locus_tag="KOU88_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBK3210060.1"
                     /translation="MKFVIVTGLSGSGKSETMRALEDMGFYCVDNLPPALITKFAELC
                     YQPNSSIDKVALGIDIRGRKFFEALHESLNYLEKENYEYEMVYLDCNDDVLLKRYKMT
                     RRNHPLAKDMQIPEGIKMERKIMEPLKELSTCIIDTTNMKPKDLKEEIKKIYSSGEDN
                     PNLTISVVSFGFKHGILADADLVFDVRFLPNPYYVEELRAKTGDDKEVRDYVMNSKIS
                     EEFYVKLLDMIHFLVPQYIEEGKQHLVIGVGCTGGRHRSVTITNLIAEDLSNKGYRVV
                     KKHRDSMLR"
     gene            complement(146442..147155)
                     /locus_tag="KOU88_000133"
     CDS             complement(146442..147155)
                     /locus_tag="KOU88_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBK3210061.1"
                     /translation="MKILADYHTHTLYSHGKGTIEDNVKVAISKGIKTIGISDHSYKH
                     IAYGVKKKDILKMREEVDYLNDKYTDINILLGMECNILDDKGNIDMDDKFIRDFDYIM
                     AGYHFGSTPTSLRSLLNHCNNYIFKTEKAKEYNTKAVINAISNNDIFIITHPGDKGDV
                     YIEEVAKTAKKTNTRLEINSSHSFLNVNQLNKIKGLENKFIIGSDAHCPERVGDFELA
                     MKTISDSNLDISLVENIII"
     gene            complement(147159..148073)
                     /gene="murB"
                     /locus_tag="KOU88_000134"
     CDS             complement(147159..148073)
                     /gene="murB"
                     /locus_tag="KOU88_000134"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBK3210062.1"
                     /translation="MNNQDIYINLLNILSKEDIKVDEPMKKHISFRVGGPADILVRPR
                     TEEQLKNVLKLVKEESIPYLIIGNGSNILIKDGGIRGVVIELADNFNSYEINDTRMTA
                     QSGALLSVLGKALQKQELKGFEFASGIPGTLGGALAMNAGAYGGEMKDIVKSVRLMDM
                     EGNIFELSNEQMEFGYRKSIISKNGYIALSAELELQEGNYDEIKSLMDDLATRRITKQ
                     PLNFASAGSTFKRPTGYFAGKLIEETGLRGLTLRGAQVSEKHCGFVVNQGEASAKDIL
                     DLIYVIKSAVYAKFGVMLEEEVKILGED"
     gene            complement(148346..149116)
                     /locus_tag="KOU88_000135"
     CDS             complement(148346..149116)
                     /locus_tag="KOU88_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBK3210063.1"
                     /translation="MSKGFLTPGETAQATISAGIKKANISTQNAILLGLFGGAFIGFG
                     ALGSMIVSQTFGKIDPGVASFLSAMVFPVGLMLVVVAGAELFTGNTLMAIALMDKKIT
                     LGKMLRNWGLVYFANLVGSILLVALVFYSSTLTGDAATKAIAVAEAKVNSTIASMFLK
                     AILCNILVVLAVWMATASQDIMSKLASCWTVIMLFVLCGFQHSVANMFFIPMGMALGA
                     NITMVQFITNLVFVTLGNIVGGSIVVGGIYYLCYVKNS"
     gene            149434..150915
                     /gene="cls"
                     /locus_tag="KOU88_000136"
     CDS             149434..150915
                     /gene="cls"
                     /locus_tag="KOU88_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBK3210064.1"
                     /translation="MFDISFFEMSIYEIAVTTIYIINFMVILNLIFREKRNINTTLTW
                     LLILVLIPALGFILYIAFGRNISKNNMFRLKEKDDKIIKSNILDTQVKLQSTSEIDSD
                     IHQHKDMIYALANSNNAHYTNNNDVWIYAESSQFFNSLLEELKKAKKYINIQFYIFKD
                     DKIGTEIIDILIDKAKEGVEVRLLFDAVGGRTLKNSTLSRLKESGVKVGSFFPSFLKI
                     VNFNLNYRNHRKIVVIDGKVGFVGGYNVGDEYLGRNPKFGLWRDTHTKLTGDCVIDLN
                     MRFILDWRYTTKEDLDLEKYFIEEDTNSNHPSENIGIQIVSSGPDISELDEIKYGYLK
                     MIQKARKYIYIQSPYLILDSTFIDTLKIACLSGVDVRVMIPSKPDHPFVYWASYSYAG
                     ELLKFGAKIYTYGQNAFLHAKTIVIDDSICSIGTANMDIRSFELNFEVNAFMYSSKKA
                     LEQRIIFENDILNSKEITLDIYNSRSTYIKIKESISRLLSAVL"
     gene            151233..151730
                     /locus_tag="KOU88_000137"
     CDS             151233..151730
                     /locus_tag="KOU88_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase subunit E"
                     /protein_id="HBK3210065.1"
                     /translation="MCDFISHNKQLFDELDIFIDSLATKEGALIQVLHEAQGIFGYLP
                     KEVQLHVARKLGVAPAKVYGVVTFYSYFTTEPVGKYKISVCLGTVCFVKGADKILSAF
                     EKQLGIKVGETTSDFKFSLEGLRCLGACGLAPVVTVNGKVYGKVKPDQVSEILDTYRE
                     LELNC"
     gene            151747..153633
                     /locus_tag="KOU88_000138"
     CDS             151747..153633
                     /locus_tag="KOU88_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBK3210066.1"
                     /translation="MRKVNSFDELKVLADELKPNLSLRKNYSKENVLRRELLVCCDTG
                     CTSSNSLEIVSELENEIKKSGIQDKVSVRLTGCFGFCAQGPIVKVYPDNVFYVKVEPS
                     DAEKIVQSHLIRNTVVEELLYEEESLSKKVEEQEEMSFYKKQLRIALKNCGLIDPDSI
                     EEYIANDGYLALGKCLTSLTPQEVIAEVKTSGLRGRGGAGFPTGSKWEAASKNPAGPT
                     DKKFVVCNADEGDPGAFMDRSVLEGDPHSVLEAMAICGYAIGSDTGYIYIRAEYPKSI
                     ERLKVAIAQAEKYGLLGENILGTGFNFKLELKYGAGAFVCGEGTALMHSIEGRRGEPR
                     MKTYSSSKSGLWKSPTCLNNVETFANIPAIILKGGDWFANLGTEDSSGTKVFALGGKV
                     ENVGLVEVPMGTTLRDIVFEIGGGIPEGKKFKAVQTGGPSGGCIPTEHLDTPIDFGSL
                     SSIGSMMGSGGMLVLDESDCMVDIAKFFLEFTVEESCGKCTPCRIGTTRLLEILTKIT
                     EGNGTLQDLDDLENLAETIQTASLCGLGKAAPNPVLSTLQYFKDEYIAHVVDKKCPAG
                     KCQNLLSYFITDDCKGCTKCSRVCPAGCITGSVKEQHTIDTSKCLKCGACIDNCTFNA
                     IIKK"
     gene            153656..155437
                     /locus_tag="KOU88_000139"
     CDS             153656..155437
                     /locus_tag="KOU88_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase small subunit"
                     /protein_id="HBK3210067.1"
                     /translation="MSLVNLTINGKHVSAPSGTSILDAAKLINIKIHNLCHLHMNEID
                     KLDTCASCRVCMVETERGLVPACGTVIKEGMKVQTNSAKALNARRTIVELLLSDHPQD
                     CFVCEKNGDCELQTIAADLGVRKIRYQGSKSFAGKDTSTKSLVKDHSKCILCRRCETV
                     CNDIQTVGALSGVNRGFNTLVSTFFNSDMVETECTFCGQCISVCPTGALTEVDNVPKL
                     WDVLNKKEKTIVVQVAPAVRVAIGEEFGLEPGSISTGKMVAALKALGFEHVFDTNFGA
                     DFTIMEEATEFIERIQKGENLPILTSCCPAWVNFLEHNYPDKLNLASSCKSPQGMFGS
                     IAKNYYAPKILGINPEELYVVSVMPCVAKKYEASREELSESGILDVDLSITTRELAKM
                     IKEAAIDLPNLQDQDFDNPLGKSTGAASIFGASGGVLEAALRTSYEKITNKTLDNVNF
                     TNVRGLKGIREASIDVDGTTVNVCIVNTLKNARKIMDKVRSGECKYHIIEVMACPGGC
                     VGGAGQPYHHGNTEIVDRRANALYEIDRNKAIRKSHENPDLQAIYKDFFGEPNSDVAH
                     KYLHTHYFDKSCVYGECPQECACEEAK"
     gene            complement(155577..157373)
                     /locus_tag="KOU88_000140"
     CDS             complement(155577..157373)
                     /locus_tag="KOU88_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate oxidoreductase"
                     /protein_id="HBK3210068.1"
                     /translation="MGIEYFSKLLESSTEKELLLSKKSNNISTARLISFLIVIAGFAI
                     GFYNKNIVGIFVGVLSIIIFIALLVIHSKVKEEETYFKSKSEVLNKYIKRFGDGWKEF
                     KIDGKEYLKDENSQAKDLDLFGRASLYQYICVANTSYGKNFLAKYLWNENPDENVILE
                     RQRAIKELLSKDDFSIHIQTLSNIIGKEQKNNSDSSIESFIEYGENKNVYIPKWMHIF
                     TWGLPTATILSFIFCMLGFLPVLPVFLLFIIQLGFSGFGYPRLMQTLAPLFSFSRSIQ
                     VYEKMFEVLEKETFESAYLKELQDKLSKGSGVSRGVKQLNSIGNAVNLRYNQILYIIA
                     CGVLMWNYHCAEALERWKGIYGNQIRDWFESIGEFEALISLTVVSHVKENTCFPVIKY
                     EDTPRLKVEEVYHPLIAEKSVIANSIQLNSQTCIITGSNMSGKTTFLRSIGVNLVLAY
                     AGAPVCAKSFDATCMAIFTSMRIQDDVSQGISTFYAEILRIKSMIQYSLKELPMLVLV
                     DEIFKGTNSADRIIGASEAVKKLSKPWVISMVTTHDFELCDLSGSGDVEVVNYHFSEY
                     YVDDKIHFDYKIKDGRCKTTNAKQLMRMAGIL"
     gene            complement(157587..158516)
                     /locus_tag="KOU88_000141"
     CDS             complement(157587..158516)
                     /locus_tag="KOU88_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBK3210069.1"
                     /translation="METSNKVSIREIIKELKLKVVYMPDDVDYYVYSQDINRPGLQFA
                     GYFDYFAYERIQIVGKTEYNFFGLMDSHIREEVLDRFFSYEIPALIISRDLEIKPDVI
                     EKAKKYKRILLSTNRNTTRLINRLSNYLDNKLAPHTTIHGVLVDIYGIGVLIKGESSI
                     GKSETALELIQRGNRLVADDAVEIRKLDESMLVGQSPELIRHFLEIRGIGIIDVRSLY
                     GVGAIKNSKMIDLVVHLEAWDETKYYDRLGLDKEYEEILGVNVEKLVVPVKPGRNTAM
                     ILEVAAMNFRQRGMGYDAAQEFTKKLSKLIDTK"
     gene            complement(158516..160333)
                     /gene="uvrC"
                     /locus_tag="KOU88_000142"
     CDS             complement(158516..160333)
                     /gene="uvrC"
                     /locus_tag="KOU88_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBK3210070.1"
                     /translation="MFDIQEHLKKLPSEPGVYLMKDKYDHIIYVGKAISLKNRVRQYF
                     QSSKNHTSKVKSMVKNIYKFEYIITDSELEALILECNLIKRYRPKYNVVLRDDKTYPY
                     IKVTTNEDYPRILKVRRVLKDKAKYFGPYTNITAVNDTLELISSTYPIRSCKIDIDKA
                     IKNKTRPCLNLHINKCLGPCTGNVSKEEYGKMIEEIIMCLSGKEEKLMELLKEKMNES
                     SMNFRFEEAAVYRDKIKSLEEMIQKQKIDATVSDLNQDVVAMARAHNEACVQVFFIRN
                     GKIVGREHFILEGVMDSPRASILSSFVKQFYNEQEYIPKELIIEDEIEDSSILEEWLS
                     SKKGQKVTIRVPQKGEKKSLVEMVRKNAVEYLEKFSDMNKRKYEKSIGALEELKQILN
                     LEKLPIRIEAYDISNIQGVDSIGSMVVYTNAKKDKKEYRRYKIKTVIGPNDYDSMAEI
                     VDRRLKHGNLPDLILLDGGKGQVSAVKKVLELNDVDIPLWGMYKDDKHRTKGLICKEK
                     EIELDKTTNLYRFIASIQEEVHNYAITYHRSLRNKALTKSILDDIQGIGEKRKKSLLN
                     HFKDVDAIKKATMEELLEVDGMNKSIADNVYNFFRKEEN"
     gene            complement(160592..163417)
                     /gene="uvrA"
                     /locus_tag="KOU88_000143"
     CDS             complement(160592..163417)
                     /gene="uvrA"
                     /locus_tag="KOU88_000143"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBK3210071.1"
                     /translation="MEDKIIIRGAKEHNLKNIDLELPRDKFIVFTGLSGSGKSSLAFD
                     TIYAEGQRRYVESLSAYARQFLGQMEKPNVEYIEGLSPAISIDQKTTSKNPRSTVGTV
                     TEIYDYLRLLFARVGDVYCPTCGEKISQMTIQEIVDKMLDFPDRTKLQILSPIVRGQK
                     GTHKKVFDNIKKEGFVRVRVNGENYEVSDDIILNKNQKHNIEVVVDRIVIKDGIESRL
                     ADSIETAVKLSDGLVIAQIIDGEEILFSTKFACPEHGIGIEELSPRMFSFNAPFGACD
                     VCNGLGESKEVDPELVVPNKDLSIKQGAVAAWGSTGVNDDTYYSKMIKSLAEHFNVSL
                     TTPFKDLPDDFVEELLYGKDNIIVEFTYESKFGGTRNYKSYFEGVIVNLERRYRETNS
                     DYMRDKIEEYMAERPCPKCKGMRLKKEVLSVLVDGKNIMEVTNLSVNELIDFMENINL
                     TEKQRFIAHEIIKEIKGRAMFLRDVGLDYLNLSRKAGTLSGGEAQRIRLATQIGSALV
                     GVLYVLDEPSIGLHQRDNDRLITTLRHLTDLGNTLIVVEHDEDTMREADYVIDIGPGA
                     GIHGGEIVAQGTLDEIIENENSITGQYLSGKKQILLPETTREGNGSFIEIVKASENNL
                     KNIDVKFPLGKFTCITGVSGSGKSTLINDILYKGVASKVNRLKQRAGKHKEIKGIESI
                     DKVINIDQSPIGRTPRSNPATYTGVFDFIRDIFASTNEAKARGYKKGRFSFNVKGGRC
                     EACKGDGIIKIEMHFLPDVYVPCEICKGERYNRETLQVKYKDKTISDILDMNVEEAVE
                     FFENIPNIKRKLETLMDVGLSYIKLGQPSTQLSGGEAQRIKLAAELSKRPTGKTLYIL
                     DEPTTGLHMADVDKLIQVLQRLADTGNTIIVIEHNLDVIKTCDYVIDLGPEGGDKGGT
                     IVATGTPKEVSKVDGSYTGQFLKKYFS"
     gene            complement(163436..165406)
                     /gene="uvrB"
                     /locus_tag="KOU88_000144"
     CDS             complement(163436..165406)
                     /gene="uvrB"
                     /locus_tag="KOU88_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBK3210072.1"
                     /translation="MDFKIKSDFKPTGDQPEAIKSIVDSINRNEKFSTLLGVTGSGKT
                     FTMANIIQQVKKPTLIMAHNKTLAAQLYSEFKEFFPDNAVEYFVSYYDYYQPEAYVAH
                     SDTYIEKDASINDEIDKLRHSATASILERRDTIIISSVSCIYGLGDPKDYKELMLSIR
                     PGMQRDRDDVIKRLIEIQYERNDINFTRGTFRVRGDILEIFPASNDEKAIRIEFFGDE
                     VDRITEIDYVTGKIVGTRNHVVIFPASHYVTTPERIEKAIVEIENELQEQIKFFKEND
                     RLLEAQRIEQRTKYDIEMLKEIGFCQGIENYSRHITGRSEGERPYTLMDFFPDDYLII
                     VDEAHVTIPQVRGMYAGDRSRKTSLIENGFRLPSALDNRPLNFQEFEGNINQMLFVSA
                     TPGPYEIQHSETIAEQIIRPTGLLDPIVEVRPINNQIDDLVGEITKTIEKNERVLITT
                     LTKKMSEDLTNYLKEIGIKVKYLHSDIVTLERTEIIRDLRLGKFDVLVGINLLREGLD
                     IPEVSLIAILDADKEGFLRSETALIQTIGRAARNENGRVIMYADRITDSMQNAIDETK
                     RRRDIQNLYNEEHNIIPKTIQKNIRDSIEATKVAEEEVVYGISDTDDKDEIRANIDKL
                     KSEMMEAAQNLQFERAAELRDKVKQLEEKLEK"
     gene            complement(165593..166855)
                     /locus_tag="KOU88_000145"
     CDS             complement(165593..166855)
                     /locus_tag="KOU88_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBK3210073.1"
                     /translation="MTKVIVLSVDSLFEKDLEFVKNLPNFKSILENCSIVKNINCVYP
                     TLTYPCHTSMVTGVYPKKHGIYHNEKFDPNKENKDWYWYSKDIKAKTIIDVAKENNLT
                     TSSVLWPVMGANPNIDYNIAEIWAPSREDDPRETFERSSSKVIMDGIYNRHCHYIDWK
                     LEPNMDLFGVNCSVDIIKEYKPDLMLIHLATLDHTRHNYGLFNDEVDKALKMNDKWLG
                     DIIQATKDAGTYKDTNFIILGDHGHLRVDKVINPNVLLKSNGFIKVENGEVKDFDAYV
                     NSSGISAQIIVNNLDRLTELRELLEEFKEELFIENIFTKEEASNLGLEGDFEMVIEGL
                     EGISFGNDFEGSIIKDSDIKDYKFAVATHGHLPTKGNRPPFIAFGPNIKGGVVIEEGD
                     LRAHAATILKMFNLKLDGVEKEAFDFIM"
     gene            complement(166918..168222)
                     /locus_tag="KOU88_000146"
     CDS             complement(166918..168222)
                     /locus_tag="KOU88_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3210074.1"
                     /translation="MKLKRKLATGLAITLLLGSLVGCSNSNDANASKGEKTDSNITKI
                     DFWAPLGGTNGETAQKMVDQFNSEHKDVQVNMLKQKDYYENATKLQAALTSKDQPDVT
                     LLEITQTGTFASAGALVDMSKYFDKTYQERFFSGLLTNSYYEDKFVGMPFNRSTPILY
                     INKDMATKAGLDPSGPKSWEELKDYASKMTNKSEDTYGFETPIDIWFYEAMVMQSGGE
                     ITNGKKVAFNNEAGQAPVKFWQDMMKAGIMKMPPGEDYNAWDVAKQDFVNGKVGMIFT
                     STADLAGLMQQTEGKFEISTAFLPKNQKYATPTGGANLVMLEGGTDKEKEASAEFIEW
                     MTQTDKIVQFSSSTGYLPTTEDATNSEKLQTLYKEKPQYKVATDQLQYAVALPMLNGY
                     KEATDKLMDEIKKGLTDLNANPKDVVSKGTSAMQAVIDKTNK"
     gene            complement(168253..169113)
                     /locus_tag="KOU88_000147"
     CDS             complement(168253..169113)
                     /locus_tag="KOU88_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK3210075.1"
                     /translation="MDIIQPIKKDKVDIKKIASKSIEILILLLLSAIFIFPFIWMLST
                     SFKNPQEMMQLPPTIIPNDIVLENYSTAWHSGPFFRYLLNSVFVTGSVLIVQFLVMVP
                     AAYAFSKIKFKGEKMLFGLLLVGLMIPPQVTFLPVYMMMSKFGFINTYVPLIIPFMTS
                     SFGIFLLRQNFMQISDEIIEAAKLDNASDLKIMFRIMVPMAKPAVITFILFNFIYHWN
                     NYFWPLVMTNTDAIRTLPIGVALLKSSEGITAWNVIMAGNIILILPIILVYIFANKKV
                     KEAFMYSGIK"
     gene            complement(169157..170026)
                     /locus_tag="KOU88_000148"
     CDS             complement(169157..170026)
                     /locus_tag="KOU88_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK3210076.1"
                     /translation="MKKQFNKAYLYITPAIIGTLLFIVYPIIKTISLSFKSGSLLSST
                     FENVGLNNYTELLKNPEFIQTITNTAIYTFFMVTISISLAIVLAVWLNKNSIIHNLTQ
                     SIIFTPHVISLVSVAVLWLWIMEPQYGFLNWILSTLHLPTSKWLSSESSALMSLILIG
                     IWKTLGYNILIVLSGLKSIPNYIYEASKLDNANKITNFFKVTLPLLSPTIFFLMITTT
                     TASFQVFDEISIMTQGGPVGSTNMLSYYIYESGFIYYDIGQASAASMFLLAIVMIATY
                     ANFRLLSKKVHYQ"
     gene            complement(170010..171080)
                     /locus_tag="KOU88_000149"
     CDS             complement(170010..171080)
                     /locus_tag="KOU88_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210077.1"
                     /translation="MADIRLENVTKSYNKKNTVIENLNLTIEDGSFTVLVGPSGCGKS
                     TTLRMIAGLEDITSGRLKIEENDVTKTDASKRDIAMVFQNYALYPHMTVRENIEFGLK
                     NKKVEKEKREKLITEVIDVVGLREYLNVKPGNLSGGQRQRVALARAMVKNPKVFLMDE
                     PLSNLDAKLRNQMRTELIQLHQKLKSTFVYVTHDQVEAMSMADKIVIMNKGKIMQIGS
                     PKKIYQNPKNLFVAQFIGSPCMNILDIKNDIKFGFRPEKATLESINIDGKNDDVFSLF
                     GKVVTKEVLGNETIYCLSVLNREIRVKTENDIFDIGRTLRISVLEKDLYYFDKNGERI
                     EDVKVCKSMYSKIKGDIYEKAI"
     gene            complement(171535..171651)
                     /gene="rrf"
                     /locus_tag="KOU88_000150"
     rRNA            complement(171535..171651)
                     /gene="rrf"
                     /locus_tag="KOU88_000150"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT        54160 a        31220 c        21472 g        64821 t
ORIGIN      
        1 ataaatatag tatttacttt ttaatgctat ttaattacat atttttccta aatacatagc
       61 atttttgtag aaaattttat atacttaaat tgttattatc atgaagtaga acaaaaaata
      121 aaaaaggagt tttgatatga acaatgaaaa tgaacagtta aaaagtgatt tactcatcaa
      181 cgatgaaaaa atcaaaaatc ttaatttcaa gataccctgg tattattctt tatggactat
      241 atccatacta attctttcta cgttttcaac atactctata tcatttatag ttgcaataat
      301 attcttattt aaaagaaata agataatgaa aaaacataaa gatagcatta gtatactatt
      361 atctgatgtc gaaaaaatca ataataaata tattttatta aatgatgaaa ttaaaatgaa
      421 agaaaaacac tttgaagatt tatgtgaatc aaatgaaaat aagttaaaag aattatccaa
      481 tctattagac aaaaagaaag ttgaaattga taaatttgat tcagaaaacc aagataaatt
      541 taaacttatc gaagaactaa aaatagaaaa agaaagactt gataatctta taaaagataa
      601 aaatatactt aaagataata ttaatacttt aaattctcat ttagaagaat taaaaaatga
      661 aagggaggag cttagagata taaacacaac tttaaaaaat aaaaaagaag aactaaaaag
      721 attatcagaa gaattaatac agactgaaga tgaggttctg cttcaatcat ttggattata
      781 taatccaaaa tatgattttg aaaactctga tgaatatatg gaaaaattaa aagaaataag
      841 agaaatgcaa aaactattaa taagaaataa aacaggtgta aaatattctg attcttggac
      901 tgttgatgga agtgttcaaa aaggtagaac tatgactaat caaaatatta aaacagctct
      961 taaactcttc aatagtgagt gcgacattgc tatgtcaaaa gttagtttta aaaatattga
     1021 ttctatagaa aaaagaatac gaaaagcatt tactgataca aataaattaa atacttcaaa
     1081 taaggtttct ataaaagaaa actatcttaa tttgaaaata gatgagcttt atttatatta
     1141 tgaatacctt caaatgaaag aagaggaaaa agaagaacaa agagctttga gagaacaaat
     1201 gaaagaagaa gctcttgttc aaaaagaaat agaaaatcaa aaaagaaaac taaaaaaaga
     1261 agaattacaa tttaagaatg aattacttag actaaaatca actataccag aagatgaaaa
     1321 cgacaaatta gaatgggaac aaaaaatcaa ttctatagaa gaaaaactag ctttactatc
     1381 aaaagattta gatgatgtat taaatagaga acaaaataca agagcaggac atgtatacat
     1441 aatctccaat atcggtagtt ttggagaaaa tatatataaa ataggagtaa ctagaagatt
     1501 agacccaact gagagaataa atgaattaag tagtgcatca gttcctttta aatatgatat
     1561 acatgcgact atatttagcg aagatgcacc taaattagag tcagctttac ataaagcttt
     1621 tgataataaa agagttaata aggtaaataa tagaaaagaa ttcttcgaag ttactcttga
     1681 tgaaataagg tcagaagttg agaaaaattt cgataagact gtagaatata caaaattagc
     1741 agaagcacaa gaatatagac aaacgttaaa aatacaagaa ttaaataata aattagctta
     1801 aatatattca aacaattata atttaataaa atattatttt tgaatatctg taccaatttg
     1861 tgatataata atagcaagga gataaaattt actttttaaa aggtgaattt ctctaattga
     1921 ttagaattta aaagttattt ctttaaatca cccttattgg cgtttgggtg attttttatt
     1981 ttctcgtaaa tgtaagctga cacaatacca gccactatac tcaataaaaa gttaattaac
     2041 atataaattc acctccttcc tacattggaa tttggcgttt atatgagaaa atcaccctta
     2101 gcttttcaat tttattctcc ttgctaaaaa tattataaca cataactctt acatatttta
     2161 cctatatatt acatttaaat ttttatttta gtttattctt attatttaca cgtatataag
     2221 cacgttttat aatataattg taaggggttg atataatgaa aaaagatata tatgtatatc
     2281 ctgctatact aagctacgat gagaatggta tctctgtaga atttcctgat ttaccaggtt
     2341 gttacacatg tggagataca acagaagaag ccttaaaaat ggcaaaagaa gctctagggc
     2401 tacatttata tggcatggaa gaagataatg acataatacc aaattcaaca actatagata
     2461 aattaaactt agagaaaaat caaataccta ctttgataga aatatatatg ccaattcaca
     2521 gaaaagctat agaaaattac tctgttaaaa aaacgctgac tatccctcag tggcttaatc
     2581 gagaagctga gaagcataag gttaatttct ctcaaatact tcaagaagct ttaaaaaatc
     2641 accttaacat tcattagaaa ttagagcagt ctaactgctc ttttatataa aacatataaa
     2701 cttataaagg ggcgtacata tatgaatatc aaatcagctt ttataagaaa aagaggggga
     2761 aaattctatg tatatgtgga gtacatagag gaaacaactg gcaagataaa acagaaaagt
     2821 tacggaagtt atgaaaagaa aaaggatgct gaaaaacatt taattgaaat aaagtctact
     2881 ataaacaata ataagtttat tactccaagt aaaacaactc ttgtagagag gtgttataaa
     2941 tacataatgt caaatgaaaa aaaatggtct ccctatacaa ctgtaaatag aaaatcgtgg
     3001 gttaaaaatt atatagagcc tttttttaaa gatacaatat tgatagatgt aaaccctagc
     3061 cttcttcaaa tctttataga taaaaatttt gatggttctg caccatcaac tgcaaaagtt
     3121 agatataatt ttctatcttc tgttttaaaa gaagcttata ggctaaaaga aatatctgaa
     3181 aatccttgcg attttgtaaa attgccagct caaaatgtta catatgaaat tgaaatatat
     3241 aatagagaag aaacgctatt gttaatagag aagttgaaag atagtttgat agagataccc
     3301 attctcttaa tgttgctgtt aggtttaaga attggagagg tagctggtct tagatggtct
     3361 gatgttgatt tagataatag tataataaat attaaccaaa ttctcatata tgcaaatagt
     3421 aaaataactt ttaaagaacc aaaaactgca aaatcaaaaa gaacgttgtc agttccaaaa
     3481 gaattaattg aaaaattaaa aatagaaaaa ttaaaacaaa acaaaattaa attacaaggt
     3541 acacttgaaa atgaaaataa tttagtatgt ttaaatacaa atttaaagcc ttggatacca
     3601 actgcattaa gtaaaacttt tcataacttt attaaaagaa ataatttaag aaatattaga
     3661 gtacatgatt taagacatac aaacgcaagt ttgcttttgc taggaggtac taatatgaaa
     3721 gttgtttcag aaagattagg tcatacagat ataaaaataa ctatgaatag gtactctcat
     3781 gttttagagg aaatggacaa agaagcttct gataatttaa gtaaacttct atttaaataa
     3841 taaaaactga ctgtcagtta aatgtcagtt gaacctaaaa aaataggttt tgtcagttaa
     3901 atgtcagtca gttagtttat aataatttct tttaaatacc gctaaaactg cacattttaa
     3961 cacttattta tgtttgttta tacgtattta ttattcttta ttaaaataat atcctgctcc
     4021 tcttattgtt ataattttct gaggattttt ataatctttc tctattttct ttcttaatcc
     4081 attcactgca actaccacac tatagttatc ctctaagtat tcattcatcc atacatgttc
     4141 atatatctct ttagtagtca aagtcttttc aggattctct ataaaaaagt ttaacaactt
     4201 attttctgtt ggagtcaatt ttattatttt atcttctaac tttattactc cactagttct
     4261 attatattcc tctaattttg tattattttc attattattt acatatgagt tcattcttct
     4321 taaaatagct tttacttttg cgtataatat ttctaaattt agaggcttta ttaagtaatc
     4381 gtctccacca gaatttaaag catttaaaat gctttggtct tcatttatat aagtcatata
     4441 aacaattgga caagtagtta catttctaat ttttttacaa agagtccatc catcaccatc
     4501 acttagaatt atttctaaaa atattaaatc atatttattg ctaaatattt ttccaatagc
     4561 ttcttcacaa ttatatgcta aatctatact tattcctttt tcctccagaa atccttttag
     4621 cttctggcaa ttatccttgt ctccatctat tatcaatatc ttagtttgca ttataatcac
     4681 tcccaaatat cattattctt ttatattaaa taagctatta ttataaaaaa catagactta
     4741 attttattgt aaaaacagtt ccttttccta gttctgaatc tacaaagatt tctccaccat
     4801 gctctcttat aatggatttg acaatatata gccctaaccc ttgccctttt ggctcattat
     4861 tgtctctttc tgtaaagaat ctgtcaaata cctttggtat attttctgga ggtatacctt
     4921 ttccattatc agaaatttta ataattgcaa atccatcttc tttatccatt gataaaatta
     4981 tctttccatc aaatggagta aaggtcaaag cattataaat taaattctca aatgctcttg
     5041 taagcatctc tttatttatc tttgcatata tttttttctc caatacgtaa gcttcaaagt
     5101 ttacaccaca tgcttgtgta tctggcaaat tattttcata tatctcttta ataaaattat
     5161 tcagacatat tttttcacta ataccaatgc ttttatcttg tgatgtaaat tcttgcaaac
     5221 tacgtactct attttgtact tcatttgact tttgatttat agcataaaga taggttcttg
     5281 tctcttcatc tacatgaata ttaccaacct ttatcaaatc tataaatgct tgtatagccg
     5341 aaacaggtgc ctttaaatca tgtgctacat ctgccaagaa tcttttacgt tcatttaaca
     5401 atgttgtaag ttcattagtt ctcacttcaa cttcatgttc aagattcctt gtaagttttt
     5461 cattctcttt tattattatt ctattcctgt ttatcatcat aacagaaaat aaaataacaa
     5521 ttacaaaccc acaatattct gtttgccacc ctgtaaatat aggctcaaat ctattactcg
     5581 taactgcatc aaataatatg ctaattccaa aaacagtgtt tactgaaact aaaatataag
     5641 aacttatatg ctcagagcat gtctttttat atattgaaac cagcgaagac attaatatat
     5701 atataaatac aatatattta tatatgtcta ttaacttccc atatatgttg acaaagtaca
     5761 tatcatatgg aaaaagaata attggtatca ctatagatat gatactcatt gtaattccta
     5821 atggtaaaat taaaaatctg tacactttat tttcttctat tttggatata cttccattta
     5881 tacaaataat acataaaact accataaaat atgacaaatc ttcaaccgca tatgtaaagc
     5941 ttaccaaagg cagtcctaac aaatgtacaa agggatagga tacatggatg gcaaagaaaa
     6001 cacacataca tccaaaatat aagtaaattt tacttttgtt tgaaagaaac catacagaca
     6061 atgaaaatat agctattgca aaagttgtga agcaaattat actataaaaa agtaatcgat
     6121 aaaacatcat attacttatg tcctttgttt ctcctaatgc aggcggataa tacaaaccac
     6181 tataataatg tgaaaaattc gatacattga ttataatttc tgtatttttc tttgcaataa
     6241 aacttactac tgaattttta attttgggtc tatatttttc tgttcctaca tctcctaatt
     6301 tagaaaccat ttctccattt atccatactt cacttgcgga aaaaatctca ggaagctcta
     6361 aacttagtag cttatccttg ccttcatttt ttattctcat acgataagta gcattcccat
     6421 atggtgactg agtccccttt ctcatagaaa aatctggata ttgacctata aaaacatatt
     6481 ctggttttat atcttgctct gtaaaatcat tcggtttaaa tattttatga ttataaaact
     6541 cccagtcatc tatcaaaaag acaagtttac ctttagtgaa agtatcatta tctatagtta
     6601 aaattccatt acttgctcta atagacttat atgtatattt attatcatat ttatacagaa
     6661 gatttaatcc tgttattgcc aacagagaga ctatcaatac aatgagagtt ccttttagta
     6721 tattatactt tttcattgta tcaaccacat ctctttcata gtagtattaa ataaaacaag
     6781 aactatttat taattacagt atctcactta tggtacaaac ttatatcctt ttccccatac
     6841 ggtttgaatg tattgatgct ccctgcttaa agaattaatt ttttttctca tctgtgcaat
     6901 atgaacctgc actgtatgtt gatctccaat atcaggcatt ttccaaactt ggttatatat
     6961 ctctatcttc gaaaatactt gttctttgtt ttcagctaga aacaataata tttcaaattc
     7021 catagtagtt aaatctatac tttctccatc aaaagttact tttcttgaat ttacatttat
     7081 tactaacgct gaaaacttta acacattagg aactgatgta atatttttgt actgcctcat
     7141 acgagcatat attctaagtt caagttcttt taaactatag ggttttgtta tataatcatc
     7201 ccccccagct aaaaatcccc gaactttttc ttcttcatgc tcataattag ataaaaatat
     7261 tataggtatg ttaacctttt cttttatatc attgcacatt ttatatccat ctatatctgg
     7321 caatgaaata tccaaaatta tacagtctaa aactatactc tctactatat ccatagcatc
     7381 tttagcagtc tctgatgtat atacattaaa acctatatta gaaaaataaa tttgatttat
     7441 gtttaaaata tcaacatcat catctacaac cagtaaatta tacattacac cactccattc
     7501 aaaggtattt taattataat tccaagtttt atagttatta caaattataa tgttttattt
     7561 tcatatataa ctggtattat tattttataa tatctttaca aactagacta taatacttaa
     7621 gtatttttga ataattcttg aatattgtat taaacattaa gattcattat taaatactaa
     7681 ttaaagtctc cgattgttgg agaatggagc ttaaagtcat tttcacgtat aaatttatta
     7741 tttttctaga aacttgtcta ttggctagtt tgagtattga tttatatgat ttatatggtt
     7801 ataatataaa ataaattgta ttattttggt aaatatattg ttacaaaagg tttatattct
     7861 gcatctcaat gtttataaaa actttatttt cttattataa tactattatt cttttaaaaa
     7921 aatttccctt ttccaacaaa tggctacttt aaaagccaaa attttaccta tcaataaaaa
     7981 tcttaacgac taatactcct attttcaaat tttgcaacat atttgttaat tttaaaacaa
     8041 aaaaagacta tgcaatataa aaattatatt catagccggt tgcaccacta actccatata
     8101 tctctagatg cccaataata agatatactt ctcagtttct aaaatatttt tattaaaaat
     8161 cttttatata ttttcataaa tttctttttt attctaacat tgtaatatta ttttgtcaat
     8221 atttccatat tcttagagat aagatactaa aatacctatt ttatctaaag atatttatat
     8281 ttctacattc aataatagac aataccctgc aagttaaagc atcattttta tgagcttatc
     8341 tcacagggta ttatatgttt actttatatt ataactcttg ttattgatta actttaataa
     8401 atcctttttc tgaaacaagt gcttgtcctt catcacttaa tatataatct attaaagctt
     8461 tacctttttc tgacaaacca tcttctttat taactaatat aaatggtctt gatattggat
     8521 atttattagc tattacattt gcatcagttg cttcaacatc atttattttt aaactattta
     8581 ctttctcatc aacatatcca aatgatatat atcctatagc attttcattt ccttcaactg
     8641 tagtttttat atttcctgaa ccatcactta tttgtgcatc tttagttagt tcttctgaat
     8701 caaaccctac aatttcttgg aatccatctc tagttcctga accttcttct cttgatacta
     8761 ttactattgg tgcatcattt cctcctactt ctttccagtt agtaatcttt cctgtatata
     8821 tacctttaac ttggtccatt gtcagatttt ttactgagtt tgcagtatta gttatcaatg
     8881 ctataccatc tattgctatt ttagtttcct ttaatccagc acttttttct tcatctttta
     8941 aatctcttga actcattcct atttcagatg ttccttctat agcatttttt atacctccag
     9001 aagaaccaat ctgttgtact tctacactaa caccttgatt tttttcttga aacttttctc
     9061 cgatagtttc cataagagga cctattgaag ttgaacctga aacagaaact ttgcttgaat
     9121 ctcctgaatc tcctgagtta gagccacatc ctactgctaa agctccaact aacattgtac
     9181 tagctaaaag aacgcctatt ttctttttaa acattttact tacccccgct tatattttaa
     9241 ttttttgttg tcatttttct atattttaat aatacagatt ctttgttaaa tgaatattag
     9301 agcagggtta agtaaatgta aatattgtta aatacatgta aaaacttaat tttatatgat
     9361 ttattcttaa ttagattaac tttttaaagt tactttaggc agatataaac ataatacaac
     9421 tcatattatc agaagtcttc attgaagcta tcaacctatc acatcctata attctttttc
     9481 tagtttatta actaattcag caaatacatt taaggcttcc tctatagatt cttttttcgt
     9541 catatctaca ccagcagatt ttaattgttc tagtgggtat tctgaccctc cactttttaa
     9601 gaagtttata tatctatcta ctgcagtact tccttctgaa agtatctgtt gacttaaagc
     9661 acttgcagca gaaaaccctg tggcatactt atatacatag aagtttgaat aaaaatgagg
     9721 tattctcgcc cattctattc ctatttgttt atctactatt gcagattttc cataatactt
     9781 ttcatttaat ttgtagtata tattagtaaa ttcatcagca gtaagtggtt ctccactctc
     9841 taccctttga tgtacaattt tttcaaattc agcaaacata gtttgtctat gaactgtagt
     9901 tctaaattgt tctaaataat aatttaataa gtatatagtt tcatccttag acttagaatt
     9961 ttctaataaa taatttataa gaagtaattc atttaatgta gatgcaactt ctgcaacgaa
    10021 tatcttatag tccgaatata aaaatggttg acttgttctt gaataatgac tgtgaacaga
    10081 gtgccctaat tcatgaatta aagtgaatag agaattaagg tcatttttat agctcattaa
    10141 tatataagga tgtgaatcat aacttcccca agaataagct cctccttttt taccttcatt
    10201 atcatataca tcaatccacc cttcatcaaa agcacttttt atgatcttca agtattcttc
    10261 tcctaaaggt ttaagtgcct ctaatatgat atcctgtgct ttatcatatg gtatatccat
    10321 gtcaaattta tctgtcaaag gaacatacaa atcatacatg tgtatttcat tcaatcctaa
    10381 aaatttcttt ttaagctcaa catatttatt tagattagga atacttttat ctatagctga
    10441 tataagatta ttgtaaacat ctaaacttac atcatctgaa aataaagacg cttctattgc
    10501 tgaattatac tttctagttt ttgcgtaaaa tatctctgat tttattccac cataaagcgt
    10561 tgaggcaaat gtatttttat atttctcata tgttgaaaat tcaccttcaa aagcgtcttt
    10621 tctaactcta ctattcttac tttttataaa taaagagtag tttgaatgag aaagcttaac
    10681 cttattcccc tcctcatctt ctatctcagg aaattccata tctgcatatg ctaacatatc
    10741 gtatacattt tctggaattg tcgataattc tgatgtagct gcaagtattt cttcctctcg
    10801 ttcactcaaa gtatgtggtt tatctctcaa tatatccttt atatattttg cataaaagga
    10861 tagcttctca tcttttaagt attcacttaa cttattctct tctatcgcca gtatttctgg
    10921 aactatataa gaagtagcca cacctaaatc agtagataac atttctgtct tagtggctct
    10981 tccttgatta tcattaattc tagtatcttc atgttgtttc atatgagtat atacatataa
    11041 attttgaaca atcctagatg cattttcaga gatatttaat actttatata agttctcctt
    11101 actctcagaa agcttccctt tatattcttt tacttcttgg ataagatttt ttactttact
    11161 tatgtctttt tcaatttcct ctttactgga gtacatctta tctatcttcc atttgtactt
    11221 ttcttctatt gtacttctat cagttcccat atcatacacc tctattttaa tttgttttat
    11281 attttattca ctttacaaaa tatattgtat atattttagt ccaaataatc tacatttatt
    11341 actccttcta tcatatttat ttctttcata acgtcgtgta agtgtattct cttagcataa
    11401 gatacaaaaa aattaacctt ccagtattct tcattacgac attctatttc catatttctt
    11461 acgataagtt gatttttttc aaatttatca tataaaaaag gtatagagtc caaattgctt
    11521 aattttaata tcaacacatt cttttcttgg ctaaataaaa acgtattgat tatcctaagc
    11581 acaaataatg ctatcattac aaataatcca cctagaattg ccaattcata ataaccatat
    11641 ccaactgcta taccaataca tgcagttgcc cacatcccag cagctgtagt aagccctttt
    11701 actccacctt tattttttaa aattgctcct gcacctaaaa aaccaattcc agataatact
    11761 tgagcaggca ttcttgctgg gtcagcattt gtatacaaat tataatcaaa gaataattga
    11821 atcgaagtta ttgaaacaat acaagaacct attgcaatta gtatatgtgt cctaaatcct
    11881 gcaaactgtc ttattttttc tctctctaag cctattattc ctcctattat tagtgctaat
    11941 agtaacctta ttgctatctc cttacttcct atatcaatca taatataaaa ccctcctgac
    12001 ttaattacaa cttatgtcct acagataatt tacacatcag aaatactatt ttatatctta
    12061 atattattat taatatatgt aaaatatagc catctgttaa tttttgatac aaaaaaaccc
    12121 acaactgtgg gctatttgct taggtacatg tatttattta ttaatatatc tattttctta
    12181 cttgattcta ctaactcttc ttgaaatatt tctggatatt ctatgtatgt atttatctct
    12241 tccctaactg cttcaatctc attttttaac gcttctaatt cattgttcgc cataataatc
    12301 accactatta caaatttgta tatttttata tacattttat caaacaatat tatattttgt
    12361 caatattatg tcaataaaac ttactataaa aatgctttaa tttaggtatt gtatacctgg
    12421 atactaagcc tacaaacata ccagttacta atgatgccat taacataaat ggtaagtacc
    12481 ctatagcaag tatattttct atgattaaac ttgcaactat taattgacct atattatgcc
    12541 ctattgcacc tataatgctt atccctatta gtgataaatc ttttatttta ctcgctaaat
    12601 acataaataa aagactcaga taagctcctc ctatactaaa tagtagatat gataaagggc
    12661 ctgcaaatat tgatgacaaa attaccctga tagtaacaat tataacagta tctttgacac
    12721 ctaacaacat taatgaaatt aaagttataa tattgctcaa acccaatttt gcccctggaa
    12781 atataactat aagaggattt ggtatatatg tctctaatac atataaagct aaactatacc
    12841 ctatcataag acctaaaaat gtcatttttc tagttttcat taagttaact cctccaaatt
    12901 ttatctatca tcttacatta taatacaaaa tatataaaaa cacctaattt agactaaaat
    12961 atttttaatc tatttagaat aaatattagt tatttcaatg tgcaattacc tctataaatc
    13021 ttgacttttt gtatcatact tgttacaatt ttaatgataa tgaatttcat taggaggtgt
    13081 taataatgac tgtttacgat ttaaaaatag gagaaaaagg atttattaat agtatagatg
    13141 gagatattaa attatctaaa agattgcttg cacttggatg tataaatagt actgaaatag
    13201 aagttaaaaa ggttgcccca cttggagacc caattataat tagatttaga ggctttgacc
    13261 ttgcgattag aaaatctgat gctaaaaata tttctttaca ataatagagg aggagctacc
    13321 cgtgattaat gtagcattat taggaaaccc aaatgtcggt aaaactactg tttttaatct
    13381 acttacaggt tcaaatcaat atgtaggtaa ctggcctggt gttactatag aaaaaaaaga
    13441 aggatttctt ggaaaagaga taaaggttgt cgatttacct ggtatatatg caatggatac
    13501 tttctcaaat gaagaaaagg tttctaaatc atatttagaa aatgaagatg ttgatgtaat
    13561 agtaaatgta gttgatgctt ctaatttatc aagaaacctt tacttaacaa ctcaacttat
    13621 gcaatttaac aagcctatag ttatattgct taatatgtta gacattgcag aatctaaagg
    13681 agttaatata gatgccaaaa aattaagtga agaacttgga gtaattgttg ttccaattat
    13741 agcaaaaaag aaaaatggtg ttgataggat agaagaagag attaagggag ctacgcaaaa
    13801 agcttttata tatcagaaaa actttggaag tgaaacagaa acatataaaa aattagaatc
    13861 cattttatca agatgtacaa aaactacata tacacaaaag aaatctatca gtgataagat
    13921 agacaatata gtcttgaatc ctatattagc atatccaata tttattggtg tattgttcct
    13981 cttatttaaa tttacctttg actgggtcgg aggtccacta caagagggat ttgctagtct
    14041 tatagaggct tatatttctg cacctgttag tgatatgtta tctaactcta gcccatggtt
    14101 taaatcactt atagttgatg gaataattgg aggtgttggt ggtactttac cattcttccc
    14161 tttaatattt acattattct ttggtatatc gttgtttgaa gatagtggat atatgtcaag
    14221 aacagcattt ttaatggata aagttatgag aaaggttggt ctatctggta aagcttttat
    14281 acctatagtt atgggtatgg gatgttcttc tccagctata atggcaacta gaacattgga
    14341 aagcgaaaaa gatagaagag ttacagctct tattgcacca cttatgactt gtggagcaaa
    14401 gctacctata tatgcactat ttgtagctat attctttcca cataatgctg ctttagtaac
    14461 tacatcactg tatttggtgg gtatagttat ggcaattgta gttgcattat tcttaaataa
    14521 aacagccttt aaaacagagg ctgaaccatt tatattagaa ttaccagaat atagaatccc
    14581 tactatagat gcacttatta aaaatacttg gaataaatca aaaggtttct tgataagagt
    14641 tgttactgtc atgtttgcaa tgtcagtcgt aatttgggga ctttcttcat tcaatgtttt
    14701 tggatataca gaagatataa atgtaagctt cttggctact ctaggtcata ttatatctcc
    14761 tatattcaaa cctcttggtt ttgatgattg gagaacttca gttgctattt taagtggtct
    14821 tggagcaaaa gaaatcgtag taaactcttt aaatatacta tatggtaatc taactgttgt
    14881 cttaccaaca atatttaatg gagttactgc atatacattc ttgatattta ctgctttata
    14941 tactccatgt atagctgcac ttgcaactat gaaaaaagaa tatggcaata aaatgatgtt
    15001 tacatcattt gcatatcaat ttatactagc atggataatg gcttttatag ttaaaagtat
    15061 aggtggagta ctatttatgg gtaattcaat aatagaagct ttgataggtg gaataattat
    15121 agtccttgca ctctttattc tgtttaataa attcaagtct acaaaaaacg gaaatgtctg
    15181 tagtggatgt tctatttgtt ctggatgtcc aagtgctaat tcttgctcaa gtaaggaaga
    15241 cagcaataaa aaaaataatg cacactaata tataaatatt ttagtttaaa ataagataaa
    15301 agtgggtgtc tcaaaattaa ctttttagtt catgaggcac tcttttttat agaaaatcaa
    15361 atatattttc atcatttcaa cagtaaaaaa gagcttatct agtaaaaaag aggcttatct
    15421 ctattttgag acaacctctt tttttgttac ttattcagtt tcttgctacc taacttcatg
    15481 tggaacctag tatcttttgg aacacttggg tctacacctc ttaatgtagg tatttcccca
    15541 catattagtt gtataggtac tataaaatta aatgtttgat agtaaggatt atctgtgata
    15601 tcaatcttta aatttttatc attttctgta acatctctac ctatagcaaa tacattttcc
    15661 gtccaaccag aaagtacatc aatcatctta gttactctag gttcttttcc tgtatctagt
    15721 ataaatatag tagaatcact atttatagca ttatatatac catgtataaa ctcttcaaac
    15781 tcatacccag ttacaggtat tctcattgtt tccaataatt ttaatgctgc ttctaatgta
    15841 tctccatata tatcagagtg acctattatt cttatttctt tagaattaac taacttttct
    15901 ttgtttcttt caatccattg tttagagagc ttatacactg cttcaaatct attaattgcg
    15961 tctaatatct tatttatttc ctcattgtac ttttcactag atattatacc tttttctcta
    16021 gctatttgaa gacctaataa cattaagttt aactttgtac aataatatcc ttttgtttta
    16081 gctccagatt tttcttcacc acaatttact gttaatatat aatcagaaat ctcatctatt
    16141 aaagcattct tacaacctgc catagatgct attttacagc ccttatcttc agctaacttc
    16201 atagcgttgt atgtagaata actactccca ccttgagata cacctactac tagggtattt
    16261 tcattatcaa acttgaatgt atcttcagtt atcataaatg gatacatttt cacaacatct
    16321 atatctaata aattttgtaa atatggttgt acttgcactc ctgagtgata gctagtacct
    16381 gaacctgtta ttataatctt ttttagattt gttctcttaa cttcattaaa taagctatct
    16441 gcattagata taatttctct cattctaact gctgtttcta acatataatc ttgtattgtc
    16501 attttataca ccttccttat ctatatattc aataaattat aattaatttc tataacaaac
    16561 ctatagcatg taaagcgatt cctgttacta tagtgcctat agttaatttt gttacactta
    16621 cctttctctt taacatgtag tatattacaa atgcaaaggt taaaggtaac atattaggta
    16681 ttattttatc tagtatatct tgtaaaatta cttctgcacc atttaagttg aatttcagag
    16741 gagtagttat actcaacata gttgcaacca ttcctcctac aacgaataaa ccaacagttg
    16801 tagccataga cattattttc tccataagtc cctctctttg tattctttca agagaattta
    16861 cccctacttg ataaccatac ttaagtccaa atattctaag ggcaaatgct ggtatattgt
    16921 ataatagtaa gaataatagt ggtccaaaga tattaccttc ttttgcaagt gatactccta
    16981 ctcctgctgc tataatccta aatgttcccc agaataatga atcaccaatt cctgcaagag
    17041 gtcccataag agctgtttta acagcactaa ttgaactttc atcaaattct ggattattag
    17101 cattctcttc ttccatagct gctgttatac ctaatatagc aggaactact actgtcgttg
    17161 tattaaaaat ctccaaatgc ctttctattg cttttgcttg attttctttc ttattgtata
    17221 gcttctttat tgcaggtaac attgaataac agtaacctaa gttttgcatt ctttcgtaat
    17281 taaatgcacc ttgaagagca aatgaacgcc aaaacatact tcttaattct ttttttgtta
    17341 atttattcaa agtcaatctc tccttccgtt aaagtattga ttgctaattg aggattttga
    17401 ttattttctt tgttattgat ataaaagttt agtacaaatg ctacacatac tccaaataaa
    17461 gctatagcag ttatatctaa tccaccataa gatgctaaca aaaaccctat aaagaaaaat
    17521 acagacatct tttttgaaag taacatatcc ataagcaatg caaaacctac tgctggcaac
    17581 aatgttcctg caacacccag tccgtctaat ataactttag gtattgcatt tatcaatgct
    17641 gtaactttat cagcaccaat cataattgct aaaaaggttg gaactgatgt acttaaaaag
    17701 aataatatta ctggcaacca catcattatg gtaactttct taaaatcagc ttgtttagca
    17761 tagaaaactg ccttttgaga aaagtacgaa tttattattc taactaatac tccaagagat
    17821 tgtgctaaga ctgctactgg tactgctact gctaaagcaa cttctgcacc attacctgat
    17881 aatatagcaa aagctgtacc taatacacct cctgttacta catctggagg agtagctgca
    17941 cctattcctg caattcccat ccaaattaat tcaagctgtg caccaatcat aattcctgat
    18001 tttatgtctc ctaaaactaa tcctactaac atacctgtaa ctattggcct atcaagcata
    18061 gattgaccaa atatacgccc atctagtata ccaactcctg ctataatagc taacatagta
    18121 gcttgtacta acatattgaa cctccatttt aacttagttt aatttacatt aaattacatt
    18181 acatttttga ttttgttttg attttctaat aactcattta cataaacaat tccatttttt
    18241 gcttcctcta atcctgattt aactattagt tttgtatcct cctcaactaa taaaagtata
    18301 gataaaagca ttggtaaatt tactcctgtc aataattcaa atttgaaccc ttgtaaaagt
    18361 aagtttgtac atatgtttgc cacacttcca ccaaaaacat ctgttaagac aacaaattct
    18421 tcactatctt tattatttga taatatactt ctaatttctt tctcagcatc atctgctgat
    18481 ttatccgttg tcatacaaaa atactcaata ttagttaatg aaccaattat taatttactt
    18541 gtgtcaacaa gctctctgga caattctcca tgtgttgcaa ttagaaattt tttcattctc
    18601 tttctcctaa attattttat taaatctgat agttgtttct ttttgtctct aggtaacatt
    18661 ctaaattcta tatcaatccc taaatcacct atttgtttaa agttatttat atcatcatca
    18721 tcaacagcaa ctaaatctgt aagtttcttc ttcccttcct catatcttaa tcctcctaca
    18781 tttatttctt ttaatactcc tcctgaattt ttagctacaa ctaaagcatc tttggtattt
    18841 tttactaaca ctaatacatt gcttttcttt gaagaagcaa atttttctac tatttctcca
    18901 gattcctcta ccccccttat atataaagtt acattgctag gtttcgctaa gttcagtgac
    18961 atagctttca tttggtcatt ttttgcttca tcatttgcaa ctagtattac atttatacct
    19021 agtgatgttg cccatccata tgcaacctga ccatgtatca atctgtcatc aattctcatc
    19081 aaagatacca ttttccccaa atcctccatc atacattaaa atttttattg tttatactct
    19141 catttatcta taaaagcaaa aagtatgcca aatactggca tactttttta aatttcattc
    19201 acttattttg taatcttgta ttttactgtg gtagaccata gataatatta taaatatatc
    19261 ctatctctga aattggtatt tgcacactat aactcttttc tagcacacta aatgcatttt
    19321 ttattagttt tacttcacta tgatggtttt tgattaacaa atccatatca gtatactctt
    19381 caatttcagt ttgtctaact aatctttcaa tcatacaact taagtgaaca tataaagaaa
    19441 tctttttatc atttgaaagt tttttctttt gaatattttc tatagcatta attccttctt
    19501 ctattctctc tattatcttt tttgaatcta aaatagttag actatctatt actctaatta
    19561 atgaaaaatt ctttacaata gaatcattta tgttctttat tttttcattt tctactactc
    19621 tgctaaatat tctaaaaaca tcatcttctc cttttcctga tattatatcc tctaataata
    19681 taaaatctac cccattcaca tttggattgg cagttcctac tatagccatc acatcataca
    19741 tttcaaaaac tggttcttta tctcccatag aaacaagact atcataatca taaggtatta
    19801 ttttgacatc aactattcca attaaacttt cggaaagtag atgttggatt tttatagcag
    19861 tacctatccc tgtaaaacaa gatgatatta tagcatattc tttatttttt tgaggataat
    19921 acaattgtat attaggttta gtttcttcat ccataatttc tgcaatctct tcaatgtttt
    19981 taccttgcat taataaattt cctacttcta gtgcagaaat agtggatatt tggtctataa
    20041 ataacattgg gctatttatc ttattcttta aatcttcata tataagatta agagagccca
    20101 tatcaaataa cacaattaaa ccattcttta tcctatctcc ctctaggtat ctagacattt
    20161 gttttgatac atcagcaata gtagcatcta taggcatatc aatagctgta aatatatttt
    20221 tacccaacat ccgattacat acattcgcca tactactggc agtagcatat ccatgtgcta
    20281 taatagtcgc attaacttga ttaaatttca ttcttataat tgttgattta ataaatataa
    20341 tcattatgat tatatctaca ttattaagat acatatccaa tctattcgtt attaatgttg
    20401 atattttaat tattatagag tattctttgt aactctcttt ttttaaatat attagtaatt
    20461 tattttctaa agctttatac tcatcagaca attgataaga ttcgtccttc aaataaagat
    20521 aagacgaaaa tgccaataca ttattcccat catattttat attgttatta acttctaaat
    20581 ttctaaatat atcctgcatt atcgatatta taagctccat aagtacgtta ttattttcat
    20641 cattatttga aaagactaaa ttgtccatta gtctaatcat tagattagaa ctctttttac
    20701 taaatttttc ctttgttatt tcattttttt ctagtctatc aaagtaatct aaacatttta
    20761 tgaaactttg atagattata tttcttttat ttcttccatt tgacatttca atactaaatt
    20821 gtttaggaga aaagataatg cttttgcttt taccactttg gaattgaaat atatctacat
    20881 tttctatata aagatttcta ggaaggtctt gaagagtaac aaaaatattt ccatttcttc
    20941 tttgattttt tgcataagct cgtccacatg catattttat tacattttta cattcaccta
    21001 tattcccctt gaattttatc tttaaaatcg catttaatgt aatttgagtt atctctatag
    21061 gcaaaccaag taccttactt tcttcataaa taaaatgttc tacaatcttt cttttttcaa
    21121 tagtccctct ttcttctata ttgggaacat aaatatttat gggtattctt cttaaaaagg
    21181 tttgtaaaaa ttcagataga ctttctgttg tagcaaatat taatcttacc ctagcttttc
    21241 taattactcc attctctcca atcctagaaa acgtacctgt atccataaat gtaaataact
    21301 tttcctgacc ttcactattt aatctatgta cttcatctaa aaataaaaca ccaccatctg
    21361 attgttctat tagacctgct ctagattcat ttgctccagt atatgctcct tttacatgcc
    21421 caaataatag actagacaat aactccaaat tattataata ctgcgcacag tttaacacat
    21481 tgtatggaga atttttttct aatacattac tgcttacact atatttgtat attatcttgg
    21541 ctaaaaaagt ttttcctact ccactttcac ctgtcagcat tattgtaagt ccgccatttg
    21601 gataaagtac agcggttttt atttgttcga ttacttcttt taagctatta tcatatccta
    21661 tgatactatt aaacacagtc tcttgcttta ataatttaca ctcattttta agttcatcta
    21721 aattttcata aatacttttt tttgtaggtc ctactacatc atttatttta tttttaggta
    21781 aaaaaataac aggtctactg tttatcttta taagattatc agattttact aaatcattta
    21841 ataatctact tgattgagtt ctacttaaat taaacttttt tactatatct tctgttatta
    21901 tgccactttc ttttttaagt tcatcaaagt tgttaaataa tacacattca tttacaaaac
    21961 ttaaaatttc atccctcatg ttcaacctcc aatacaaata tcaataatac tataatatta
    22021 gtatatcatt tatatattta tgaaaaagat aattatattc ctatcttgat tctcttttgt
    22081 aagattgtaa aatcaaactt tttataagta taaaatctag attttttaac ataatctcaa
    22141 ggttcttatc tttccatata tctgacatag aatttatata agaatatatt tattgtattt
    22201 attataataa aaagtaaaac attataggta ttttaaaact tattagcgaa gaaaatattt
    22261 gtaactttta ttaccttatg aatattattt caaatttaaa aaggctataa ataaatttat
    22321 ttttaaataa atctacttat aacctcacaa taatacttat aaattttatt ttttcacaat
    22381 gatatatctc aaatatagtt aaaaatatat ctatttaatt attaatattt aagtaataaa
    22441 ttatcactca atcattaaat tcctttttat agtaaattac tcttatttta cttataccaa
    22501 atacatttat gtatagatat aaataagcac taaaaaaaca attcaagaaa ccatatagta
    22561 aacttaatta catctgttat ttgctcatat ctttagactt atctatacaa gcaacaatag
    22621 attttataac tgctgctcta aagccttctt cttctaatac cttaacagct tctatagtag
    22681 ttcctgctgg agaacaaacc atatctttta attcacctgg atgttttcca gtttcaagaa
    22741 ccatcttagc tgaccccatt actgcttgag atgcaaattt ataagcttgt tgtcttggca
    22801 ttccagctaa tactgctgca tctgccatag cttctataaa cataaataca tatgcaggag
    22861 aagaaccact aatacctgta actgtatcca ttaaatattc tgatactatt tctgcctcac
    22921 caaaagattc aaacagagcc ttaatcatat ttaactcttc atctgttaca ttactatttt
    22981 tacaaagagc tgacattcct tcgccaacaa gggctggagt attaggcatt actcttacta
    23041 tttttttatc tgaacctata aaactttcca gactttctat agttttacct gctgctatag
    23101 atactattat tttatttgca tctattaatt ctttaagtgg agttaaagcc ttttcgcata
    23161 tattaggttt aagtgctact attaccacat cagaatttgt aacagctacc tttgaatcag
    23221 ttgtagtatt tactccaaat ttttctttta ctttatctaa ggcaacttgg cttaaatctg
    23281 atacagttat atcttctgcc tttactaatc ctgactgtac tatgccacct atcattgcac
    23341 ttcccatatt ccctgaacca ataaatccta aagttttcat atcaaatctc cttttttcta
    23401 ttagttttat tttaaagtag ctaaattgac tttattttaa ctgcttaaaa ttatcttatt
    23461 tttataaaat ataaccttat tataactata ataaattatt cttttgtatg tattacttac
    23521 taatatgtgt atgatttact aaatataaat ttaacgattt tttcattaaa cttaacgagc
    23581 taacttccta tttagaaagt tagctcataa ttaatctaaa attttaaaaa tggaatcaaa
    23641 ccatttatac tttattatat cagttacgat tttatatagt aagaagtttt atttacaagc
    23701 aaacctagaa tgtttgctca gttcttccta ttatctcatc ttgtagtgtt ctacttaaat
    23761 tattgaaatg gtcactatat cctgcaactc taactattaa gtctttataa tcctgaggat
    23821 tcttttgagc ctctaacagt acatttttat caaatacatt aaattgtata tgatgaccat
    23881 ccatattaaa gtatgctctt actagattag ccatattatc taaccctttt tctccttgaa
    23941 ctactgatgg tgcaaatctt tgatttaata atgttccacc agtttttatg tggtccatct
    24001 tagcacaaga ttttataact gctgtaggtc cattagtatc tccacctttt tcaggtgaaa
    24061 ttccctctga aactggtttt gcacaaagtc taccatttgg acttgctccc ataatttctc
    24121 caaagtatat atgacaagtt gttggtaaca tatctactct gtattctcca ccacaaacag
    24181 ttggtctacc agttacctca ttgtaatatg cattgaatat ctcttgcatt atttcatcag
    24241 cataatcatc atcatttcca tatttaggag tcttatttga aactaaatta agtatagctt
    24301 catatccttc aaaattagca tcaagtgctt taagcaatgt atccatatcg aattttttct
    24361 tatcaaatac attatatttt attgctgtta aactatctgt tatagttcct ataccaacac
    24421 cttgtatata tctagtgttg tatcttgctc cacctctttg gtaatccttg cctttttcta
    24481 tacaatcatc aactattgta gacataagtg gacaaggcat gtgttttgca catatatttt
    24541 ctatcacagc atttccttct atttttatgt caatcatata atgtaattgc tttttaaatg
    24601 cttcaaatag ttcctcataa gattggaaat ttctagggtc tccagtttca atacctattt
    24661 gttttttact aattgggtca tatccattat ttaatgttaa ttcaagtatt tttggaatgt
    24721 tcatatatcc agttagaaca tatgcttctt taccaaaaca tccagtttca acacaaccac
    24781 tggttccacc aagtcttgca tcttctatag tttttccagc ttccataagc tcttgaacta
    24841 ttgcttcagt attataaaat gctggttgac cccatccttt tcttgatatt tcacaagctc
    24901 tctttaagaa tttttgagga gtctttttac ttatttgaac atttgaacta ggttgtatca
    24961 atttcatttc atccataaca tcaagtatta tataactaac ttcattaaca ccatcttgac
    25021 catctggatt tattccacca gtgtttatat ttgcaaaatc tgtatatgtg ctactttctt
    25081 ttaatgttat accaactttt ggtggtgctg gctgattgtt aaatttaacc cataaacatt
    25141 caagtaattc ttgtgctcta tctctatcta gtattccatt ttctacatct ctttcataga
    25201 aaggatttag atgttggtca agtcttcctg gagtaaaagc atcccatata ttaagttcag
    25261 tagtaacccc tatatgaaca aaccaataca tttgtatagc ttgatgataa gtttctggtt
    25321 tgtgagctgg tacaacatca caagtttcag caattagtaa taaatctttt ttcttagctt
    25381 catctgtttc ttcttctgcc atttgtcttg ctttctcagc atatctttta cctaatataa
    25441 ccattgcatc acaagctatt gccatagctt ctaaatctgc ttttttatta tatgcatcta
    25501 aatcattaag aaaatctagc tcttttaatc ttgcttctat gtctttcttt aaatctaaaa
    25561 atcctttttt atatattgta tctccacaaa ctgtatgtcc tggagctctt tgttccataa
    25621 actctgtaaa catacctgct tcatatgctg ctaaccactc aggtgtcatt gcatttatta
    25681 tcttatctct tgtttgtctc tttttccaaa aaggaattat ttcttcttta tgtatttttc
    25741 tagcttcttc tgatacgcta aaatttatta tatctctatt gtgcattact tctaaatctt
    25801 ccattgtatg acaacaaatt tctggatatg ttggtgctcc attaggagaa tcaccttttt
    25861 cacctactat taattctcca tcatttatgc taagagttct attctcaata taatgcttaa
    25921 atgataaagc acgaagtaca ggaatctcta cacttccctc atatttttta taagcttctg
    25981 tcataagtac tgctctttca atagatatgt gtggttctgc attaatactt tcttctctta
    26041 attttttagt tctctcaaaa gttcctcttg ccattttatt accctccaat cttagtattg
    26101 aaattacttg cttcaaacag tctttttatt tcctctaatt tttcttctga tggtctttgt
    26161 agttcttctc cttcatactt tttataaatt ttatcatact tgtgtttacc aatattatga
    26221 tatggaagaa gacttactgc ttgtatattc aaaggcttta aaaactctat cattttttta
    26281 acctctaaat tttcatcatc tacatttact cctacaatta atggtattct tatatttatg
    26341 ttagccccta attcacttaa aatcttaaca tttttcagta ttaagtcatt tgattttcct
    26401 gtaaatttta tgtgcttatc ttcatcaata agcttaatat catataaaaa caaatctgca
    26461 catttagcaa ctctttcata attttctgac tttgcatagc cacatgtatc aattgctaca
    26521 tggattccct ttgatttgca catgtttatt actccacaaa tgaagtccat atcttgagcc
    26581 attacttctc cacctgatag agttactcca ccacctgatt cttcatagaa aattctatcc
    26641 ttctctatct ctttaaccaa atctcttaca gaatactctt gaccaacaat ctctcttgca
    26701 ttgtttacac aatagtctaa gcaagtttca caaaactcac acttatcttg gtctaagcat
    26761 atttttgttt cacctttgta aattgcctta tgagggcata tatttataca tgcttcacat
    26821 tttgaacatc tttcttcatt atacaaaact tgttttgtat atgtttgact ctctggatta
    26881 tgacaccaaa cacattcaag tgggcaccct ttaaaaaata ctgtacttct tatccctggt
    26941 ccatcatgta tgctacattt ttgtaagttt ataactaatg gattcatgat ttttcacccc
    27001 taaataatat ccattccatt ttttcatttt tatgcaattc atcttcatag aatataccta
    27061 tgaaaagcat ttctacaatt acataatact atatttgtta ttattttgtc tatatatttt
    27121 tagtaatatt aaaaaatttt attttattat gatatttata ttgtttttgt aaattaaatt
    27181 taaatattta ttaaatttat ttttataaga aaatatagca ataaactata aacaatacat
    27241 cattttaatt aatttagatg tatatactat aaaaattaaa taaaaataga gactacactt
    27301 taccatgtag tctctatctt tctggtcata tttagaaatt cacatttatt gttactgctt
    27361 ttccgcctct atttactgtt atttttgtac tagcaccttt tgagaaagta tacaactttt
    27421 tatttaaatc attcatacct gttatatctg tatctcctac tttagttata atatccccta
    27481 cctttactcc agctttttct gctgatgaac cagatattac ttctgcaaca taaacacctt
    27541 tatcagtact taattttgta cctgttgctg cttcataatt tgatacatct gtacctttta
    27601 tgcctaaagt tactttttca tattttccat ttttgattac ttcttcaact atactcttag
    27661 ctgtattgat tggtattgca aatcctaatc cttctgcttg agaagctttt gctgtgttta
    27721 taccaattac ttgacctttt tgatttaaca atggtcctcc actatttcct gcatttatac
    27781 ttgcatcagt ttgtaataaa ccagtcatat tagttttttc tgtttgtata gttctatcta
    27841 atccacttat tatcccttga gtaactgttt tttgaaaatc taatccaaga ggattaccta
    27901 ttgctattga tatatctcca acttttactt tgtcactatc agcaaattct gctggtgtta
    27961 gtccagtttt atcaacctta actatagcta aatcaagttg ttggtcaaac catactactt
    28021 tacctgaagt tgttgaacca tcattgaata atacatttac acttgtagct tgaccatctg
    28081 atataacatg agaattagta agtatatatc catttgaatc aactatgatt ccagttccta
    28141 caccttgtgt ttcagttggt attgcaaaca tattactagt atcaacacta gttgttgtaa
    28201 tacctacgac agatggcgta gctttttctg caactgcttg ataaatattt tgactcttac
    28261 catcatcatt tacaactatc ggcgtagaac ttcctgtaga tttacttact aaattgtcct
    28321 taactaaaat tattgttaga aaactactaa gtattgaact tattatagca actaatatta
    28381 ctaaacttat ccctttcttt cttcttgaca tctcatacca ctccctatct taatataata
    28441 taaattatca aaatatattt ttcccaattt ttcataaaaa aaatgaaatc atctattttg
    28501 agtaaactcc tttttgatga tttcattata ttattttaat cttaattaaa ccttaactat
    28561 ttaaaattat ttaagtcttt tttctagctc ttccttttct ttttcataac ctggtttgcc
    28621 tagtaaagca aacatatttt tcttgtaagc ttctactcct ggttggtcaa atggattaac
    28681 tcccaataaa tatccactta ttccacaagc cttctcaaag aaataaacta aatatccaaa
    28741 attatactca tctagttgag gtatatttat tactaaatta ggtacttttc catctgtatg
    28801 agccaataga gttccttcaa aagctttatg atttacaaaa tctacagtct tacctgctaa
    28861 ataatttaaa ccatctaagt ctacttcctc tgaacttata gttatatttc tcttacagtt
    28921 ttcaacatta agtactgtct caaataaaag cctttttcca tcttgtatgt attgacccat
    28981 agaatgtaaa tctgttgaga aatctacaga agcagggaat aaacctttat tttcttttcc
    29041 ttcactttct ccataaagct gtttccacca ctcacttaca taatgtagtt gaggttcata
    29101 gttcactaat aactctacat cttttccttt tctatgtaaa attgttctag caacagcata
    29161 tctataacta tcattacttt ttaagtcagg attttgaaat gcttctctag catcatttgc
    29221 gcctttcatc atagcatcaa tatcaagtcc agcagcagca ataggaagta acccaactgc
    29281 tgtcaataca gaaaaacgac cacctacatc atctggtatt acaaaagtct catatccttc
    29341 ttctgtagct aactgtctaa gtgcaccttt acttgcatct gttgttgcat aaattctctt
    29401 tcttgcttct tccttaccat actttttctc taagtaatct ttaaatattc taaaagccag
    29461 agctggttct gtagtagttc ctgatttaga tattacattt acagaaatat cctttccttc
    29521 aattatatct aataaatcca taatatatgt tgagcttata ttatgcccta caaaatatac
    29581 ttctggagcc tttctttgct cttttttaag tccattccta aaagaatgac ttaccatatc
    29641 tatagcagct ctcgaaccta aataagagcc tcctatacct attaccaaaa gaacatctga
    29701 gtctgatttt atcttctcag cagatttttt tattctgtca aactcttctt tatcataatt
    29761 tttaggaagg tctatccatc ctaaaaaagt atttcctaaa ccagttttat tatgtaacat
    29821 gtcgtgcgca acatctacat atggttgcat gacatctatt tcgttttgac aaaaaaactc
    29881 tgtagcttta ctataatcaa aatttatttt tcccatttaa atccctcttt tcagcatatt
    29941 cgttttaaag agattataac acaaaatata ggtgtttttt ttaaaagttt gccacaaaat
    30001 catacatatc tcatcattta ttatcaggaa atcgattctt ctaaatgcta taactatgta
    30061 taaatttaaa aattttagtc aaataaattt acaaaaaaag aaactctaaa cgtatcattt
    30121 aaagtttctc ttttatttat cctctatttt aaattttata ttattttaaa ttaattattt
    30181 ttaatcattt cctaatctct ttgctataac ttgttgtgct atattgacag catggtcaga
    30241 tattctctct aaattactta ttacgtctaa ataaataact ccattttcta tactacatag
    30301 attattgttc aatctataca tgtgattagc tctacaagat ttctccatta tatcaacttg
    30361 ttcttcaatt tttataacct tacaagctaa atcaacatta tcagttctca ttgattctaa
    30421 tgcataagta tatgctgaaa caactctatt atacataaca tcaagttcag attgtccttc
    30481 ttctgagaaa gaaatatttg aatctattgc aacttgcgat aattcagcta tatttttagc
    30541 gtggtcacca attctttcta tatcattgac tgtattaaac aaagtatcca caacttctct
    30601 tgaatcatca tctaaaggtg cttttgaaag tttaagtaaa taatttaaaa tagctttctg
    30661 taaatcattg attaatctct ctcgcctata tgtcttatct attttttcag ttgaatgttc
    30721 tactaaagct tccatagatg catttaggct ttccttcgcc ttctcaccca tacgaagtgc
    30781 ttcttttatc gtatttgcaa gagctataga aggagtttct atcattctat catctatata
    30841 tttaatagtt ttagtttcat cttcatctat atcacctgct ctatcaggaa caagctttat
    30901 agctagtttt ataataagat ttgtaaatgg taaaagtatc aatacagata ttatattaaa
    30961 caatgtatgt gtattagcta tttgtcttgc aacattgctt gggtcccaac ttgtaaccat
    31021 gcttactact ggtttattca agaatattaa gaatatcact gttcctaaaa cattgaagat
    31081 tagatgcatc atagctgctc ttcgtgcatt tttgttagca ccaatacttg ataacagtga
    31141 agttacacat gtaccaatat tttggccata aagaattggc agtgctgctg ataatggcac
    31201 tagaccttct gctgccagtg caaccaacat acccatagat gcacttgaac tttgtattat
    31261 tgctgtaatc ccaaatccca ataataatcc aagtagtgga tatctaccaa atgtaacaag
    31321 taagtcagta aatccttgat agtctcttag tggctccact gccatcttca taaaatccat
    31381 acctgtaaat aatataccaa aacctataag tatttcggct atatttttta ttctaggctt
    31441 atttccaaat aaataaagta taatacctac acctaatgct actggggcca taccagttaa
    31501 gtcgaaagat accaattggg ctgtaacagt agtccctata ttagcaccca ttataactcc
    31561 tattgcctgt tttaaagtca ttattcctgc atttacgaaa ccaacaacca ttacagtagt
    31621 agcacttgaa ctttgtatta ctgctgtaac tcctgtacct accaaaactc ccataaatag
    31681 gttactagta agtagtttta ttatcttttt tagctttgtc ccagcagatt tttgaagacc
    31741 ttctcccata aggttcatac catataagaa cagacctaat ccacccatta gacttattat
    31801 aatgttcaaa ttatttcctc cttgtaaaga gattactgta tctaaaaatt ttataaccta
    31861 ttgtatttta tcaaattata ggagtgataa tgttaaattc atgttaaata ttaaaaaatc
    31921 attaagttta tgttaaattt ttgtattatt ggtgtatttt tgtattattt tttctgcaca
    31981 ttttatacca tcaactgctg ctgtaactat accacctgca tatccagcac cttcaccaca
    32041 tggatataga ttcttaatac tcactgattc taaagtattt tcatctctta ctattcttat
    32101 tggtgatgat gacctagttt ctactcccgt caaaacagca tcatacattg caaacccatt
    32161 caatttttta tcaagagata taaacgcttc tctcatagtc tctgttacga agctaggcaa
    32221 acattcactt aaatttgtaa gtgtatatcc tggtctatat gatggctcaa cacttcctaa
    32281 attcaaagaa gtcttattgt ttataaaatc tccaacaagc tgaactggtg cattataatt
    32341 ttttccacct aattcaaaag ctaatttttc atacttctgc tggaaatgaa cacctgctag
    32401 tggattatca ctcttaaaat cttctggcgt tacatttact aaaaatgcac tatttgcatt
    32461 tattttatct cttgcatgtt cactcatacc atttgtaact atttcaaaat catttgatgc
    32521 agatgctatg acactacctc ctggacacat acaaaaagta tatgctgttc ttccatttga
    32581 aacatgctct ataagtctat aatctgcagc tcctaaccta ggatgattat aaaaatcctt
    32641 gtactgtgct ttatttatta aatcttgtgg atgttcaact ctagctccta ttgcaaaagg
    32701 tttttgaact atttttatac ctcttgaata caacatttca taagtatctc ttgcactatg
    32761 tccaacagct aatataattg tatctgtatc tattttttca gtatcattta ttattacaga
    32821 ttgtatagaa tcatttgata caactatatc tgttactttt gaattaaatc taacttgacc
    32881 acctaaactt attatttcat ttcttatatt tttaactaca ttttttaata tatctgttcc
    32941 aacatgtggc ttatgtgagt ataatatttc atctggtgct ccaaactgaa ctaactcttc
    33001 taatactttt ctacatcgta tatcttttat tctagttgta agtttaccat ccgaaaaagt
    33061 tcctgctcca ccttctccaa attgaacgtt tgaattattt tttaattttc tagttgtcca
    33121 aaaatcactt atatctttgg ttctactgtc tacatcaaga cctctttcaa gtatgattgg
    33181 ttcataaccc atttgagcta aaagcagacc tgcaaacaaa ccagctggtc cactaccaat
    33241 taccaaagga ttattcttta attttttatc acccacaggt acatttacgt atctgatttc
    33301 ctttattttt gttacatctt ttatttttga gttaagtatt ttattttcat ctttaacttc
    33361 tacatctaca gaataaacaa attccatttt tccttttttt ctagcatcta tagattcttt
    33421 atatatacta tatttgacta agtttttttc ttttattttt agcttcttaa gtataacatc
    33481 ttttaataaa gatatatctt tatcaattcc aagttttaca ttagatactc ttaacatatt
    33541 gttttcctct cttagattgt aatataaaaa agctagggtt attcctagct ttctacaaat
    33601 ataacttcta tattctcttt tactagattt tctacccaaa tctcatctag cacaaaattc
    33661 tttattttgt ttacaacaag tgttttatct aaatcttttt tcaagttttt tactaagacc
    33721 attgcttcaa ctgatttatg caatctttca acatacagag aattaacttt aatcaataca
    33781 acccttaatt cacatacata taacttttca ctacctaagg tgatttcatc atcatattca
    33841 tatacactaa attcatatgt attttcataa ggtgttatat tttctattcc tatatagtcc
    33901 atttatttat ccttttttag ttataagacc tcttataacc ttcatattat taaacacctt
    33961 ttctaagaag ttctctgctt cttcattgtc taaaaggttt atttcaaggt tttcgttttc
    34021 tacaatacct ttagatttac aatactcttt agcaatattt attagttcat tttttttatc
    34081 catagataaa tcaaactctt tatagtctat tattatatat tgtttggtat caggtgatac
    34141 accattatta tatcctattt ctatatgata aataactgca tatatttctt ctccgttgta
    34201 cacaggtaca gctgggttag attttataaa gttcgttgat acagcaattg catttcctaa
    34261 actaagactc attattaata cctctttcta aacattatac atatattata ctatagattc
    34321 tttatctatg acttaaagct ttttataatt aattaagata tttttaaatc cttgtatctc
    34381 tttcctagtg tactagagct tatatcgtat ttctttgata tttgaacttg agttataggt
    34441 tgtcctgctt cttttttaac atagtattca acagcagctg cccaaccatt ttcagctcct
    34501 tttatatttt catgattttt cttatattca ttccaaaact ctatacatgc atctatattt
    34561 tctttttcta cattttcttt aagagtatct aaaactttac attcttcttc agctaattca
    34621 ttttctgaat taacttttgt atcgttttta tctctttctc tctttaaata ttcagctata
    34681 cttgggtcta aaagctgttg tatatacttg tatagtatat gtgtatgata aattaagaac
    34741 gacttcatat ctttgtatac atcttgatat tgattgaata gattcataat atcctttaaa
    34801 attatatctt taacctcatt tgatatactt atagttatat ctatcaatat gttagttcct
    34861 tcaatatcaa ctattctagc tatcatacaa cttccgattt taaaacttct cagaagtttt
    34921 acatcttctg tacaaagttc atttccactt aaacagtcct ttaatactat ttttccagca
    34981 gaaacttctt ttacctcata aatacttacg tatgattcaa acatactttt taatattgat
    35041 acttctgatt gacttaggtt tgcaccattt tcttcaagaa aaccaactgt cataaccttt
    35101 ttattttcca ttatgtggtc ttgtattaaa taagtattaa aaaatctttc aaatttttca
    35161 tttacactat cattttgcat tatataaaac atttctttag ctttttcaca ttcttcttta
    35221 aacttatcct gtcttgaata atcatataac tttgaatata aatctgtata ttgtttttgt
    35281 gaaagttcag tttttctgca tgctctttct gaaacaatat ctttatttaa acaacatttc
    35341 ttgtattttt tgccacttcc acaagggcat agctcatttc tccctaacaa tatgacttcc
    35401 actcccttat tattaaatta aagtacaatt tgttattata ccattttttt attaatcaat
    35461 ctatagtata agtaaatatt ctattaaatt cacttatatt ttggtacaat atattaactt
    35521 taattaggat ttcgataaaa tcatcaacaa tccctcttgt agaaatgaat tatcgtaaaa
    35581 ctaattcctc tataaaattt tattaattga taatagtttt ttactttatc tattcttttt
    35641 tgttatatga ctctaactgt cattttacat tcaacaatat tgtctttttc ttgtttatat
    35701 tcatttggaa tattttgaac atcaaaatta ttgactttta atttattaat ttctatcttt
    35761 tcaagtttat tatttagtct taacttcttc attacacctt caagtttcaa cacatttgca
    35821 agttctccat taacttttat ttctaaatta acttgttttt tattgtgatt atctaaacta
    35881 ctttcttgat taatatattc tacattcaca atatctctca gttcattttc tactaataac
    35941 actatatctt tatttgtttt tttatctaaa aatgagttat taaaattatt ttttaattct
    36001 tcatttttat ttgattcaac actttctata tatttatcat ctatatgctt attatccttt
    36061 atttgataat tatcttgatt atttatttta tttattatat tttgcttttc attcttcaaa
    36121 ctagttaggt tttcttccaa ataacttact gctatatcac ttgccaatat aataactaat
    36181 attaacaata ttttaagtag atttttttct ctattattta atctcaaaaa taatcaccca
    36241 tctaactttt tattctaaat ctataatatt ctccatctct tacaatactg tctatgtaat
    36301 aatattttat gtactttatt ttccttaaat tgtttaaaac atctaaatca ctacacacac
    36361 cttccatctc tagcttattt ttatctattg atattttagt aatactattt attccaattg
    36421 tttcatatat tttttttatt tcattaagtt ttattttaga aaatttctct ctagttttat
    36481 ctgttgttgg taaagtgtgt cttgatttat ccactagctt attttgactt atataatctt
    36541 caagttcatt tatagatttc acatacataa atgatttaaa taaaatacac gttaaaatta
    36601 agactattat tattttatag attttattac atggtttagt ttttttaaat ccattaagaa
    36661 aatttattgt tttatccact ttcacttaaa taatcattcc tatactattt atataattta
    36721 tcctattgtc ttctaaatct gcatcaaaat tattttctac ttttacttta tcttttaatc
    36781 ttaatggatt tacttcaata gatttatctg tatatttaaa gtattcttca ataaaacaat
    36841 tttctatacc atagtaataa acatacttaa aatcccttaa taatcttttt atgaactcat
    36901 atgattttcc ctcttttgat agcaagtatg tttctcttat ttttttatct tttgttatat
    36961 ttataattaa ctgacttttt ttacattcta taaatacccc ttcttctgaa aaattctcta
    37021 ttaaatttaa gtttataagc ttttgtaata tatcaaaatt tatatttata gtctttggat
    37081 tcatatttag attttctgaa atgttcttaa ttaattgaat aatactcttt gggaaaagaa
    37141 ttacttgtat attcaattta tcatttttag aatttataac tttatatttt attgaatagt
    37201 tatttatgtt tattggaatg tattgtgtta tttcaaattc aatcatgctt aatatgtctc
    37261 tttttttctt agtatttaga acttcaacat ttctaatgac tatatcctga atttgaatgt
    37321 taaagtataa atttttatat aatatttttg atttaccaat ctcctctttt acaaatctaa
    37381 ctacatcttc tatatattta atcttctcaa tcgaattact atcatttttt atatcaaagt
    37441 taatctcttt tataattgat ttatctataa aaactttttt atgacctttt cttaaaaata
    37501 caagccttat ataatcatca tttatttcta agtttagaat ttttttaatt atagccatct
    37561 ccttcttaaa taaaaataat tttaaaactt atagcaatca atataaaata ttattttgga
    37621 taaaattgct tagaatttat atttacgctt atatctgttc cgctatcatt tatgacaagt
    37681 tcgaatttac ctgatgtact ctgaggaact ggaacagtat ttaggtatcc cttttccttc
    37741 aatgtctcta cacttagaga gtctattgtc ttttcatcat cattaattgc catgctagct
    37801 gcggttacta tattagcagc attcgtatag tctgcattta atttggcact ttcttgaacc
    37861 ttactatact taactaatgc tatactagat ataacgccta aaatagttac tactacaatc
    37921 atttcaacaa gtgtaaatcc ttttcgtttt ttatttatca aatttatcaa ttaaatattc
    37981 tctccttttc aaaagtttca tctaataaaa tttatttttc tctctaaaaa ttagtaattg
    38041 catcaaacat aggaacaacc attgctaaaa taaaagtacc aataattaat cccataaata
    38101 caattagcat aggttctata aatttcatta tttgctctat tttgttattt aattcatttt
    38161 cataaaattt atttattaca tttagacttt tatctagttt cccactttct tctcctgtat
    38221 ttgccattga aataaataat tttggaaaaa tatttgctaa attcaaagat ttacctatgc
    38281 tatttccttt ttttatataa ttattggaaa tctttaacct ttcataaata aattcgttgt
    38341 ctataacact agctgacata tctatagctt ccacaatttg tattccactg ctaattaaaa
    38401 cggacaatgc ccttgaaaat cttgttgtag ctactaactg attaattttt tttataaaag
    38461 gtattttgaa ttttaacgaa ttaatcaatt tttttatatt atcatttgtt ataaagaaat
    38521 aaatgcttcc tattgaaaac aatataaaac taaatattat ataagctaag ttatttgtaa
    38581 ccactgtaga tattcccatt aaaactctag ttattaaagg tggttcaatt ccattgttgg
    38641 taaaaaccac ctgaaaatta ggtattacaa atacgaatat aaacaacatt gataagatag
    38701 ataatattat aagtattatt ggatatattg aaatagttat tattttcatt tttaatttgt
    38761 attctttatc ataataatta gataaatcac tcattattat atctaagttt ccactagttt
    38821 ctcctgcttt tatcatactt ataaagaatt tagaaaatat acctgttatt tgaaatgatt
    38881 ctgctattga gttacctttt tgaatatgat ttgatactat actaagcaag ttctttactt
    38941 ttttacttga ctgactctca atgatttcaa atatttttgt aatttcacat ccagattcca
    39001 gcaatatgcc tatctctttg caaattactc taatttcttt atcactgatt ctatttaata
    39061 ctaaataaaa cttttctaaa ttataaaata tatttttaga taatctcatg tactataata
    39121 ccttccaaat tatattaatt acaattaaat aaacttaata ttttctaatt taatacattt
    39181 aattttattt cacttaaata taatttatac tcaaacatct taattaaaat agattaaata
    39241 aagacaactg accaaacgaa gtttaactat acaattcagt taaatcattt catttactac
    39301 taaacactct tctaatgtcg ttattttttc atttattagt cttttacaac tatcttcaaa
    39361 tgttatcatt ccattatttt gtgccacatc tttaatagta ctagaatcct ccatatttct
    39421 tatacatgtc tttatatcat cattaatttc taagatttca taaattgctg ttcttccaaa
    39481 gtatccttta tcattacatt tttcacaccc tacagctacc ttagtattta catctccact
    39541 aaaattatct tttatcataa tctcatggct acaatgattg cagacttttc taaccaactt
    39601 ttgagatata acacctataa gagaggcatt taaaagatat ggtggtattt gcatttctag
    39661 taatctagct atggaagata ctgcatcatt agtatgtaaa gtacttataa ctaaatgacc
    39721 tgttatagct gctcttactg ctatcttagc tgtttctgca tctcttattt ctccgaccat
    39781 tattatatct gggtcttgtc ttaatatcgc tctaagacct acatcaaagc tcaaccctac
    39841 ttttgaattt acttgaatct gacttatgcc atccatctta tactctacag gattttctat
    39901 agtcataata tttttattta ttccttttaa atcatttaat aaggaatata ctgttgtagt
    39961 ctttccacta cctgtaggac ctgtcactaa taatattcct gctcttttat ttattatacg
    40021 atttatagat tttatagctt cctctgaaaa accaagttct aatttgtctt ttaaaaaagt
    40081 atctctatta agtatcctca aaactatttt ttcaccatag acagttggta ttgatgaaac
    40141 tctaatgtca attaaatttc cacctaactt tatatccacc ctaccatcct gaggaagcct
    40201 tttttctgtt atatccattg atgcctttaa ttttataacc gtagacaatg atggatagac
    40261 atcaactaaa aactttgata cttcctttag ttctccatct accctcattc tcactattaa
    40321 atgttcttta aatggttcta tatgtatatc acttgcgttt tcttttatag ctttttctaa
    40381 aagattttca aataattttt ttgcataatc ctcatcaagt tcaaagctat tataatattt
    40441 ttcaatcttt tcacttataa gttctttttt ctccttcttc aatataattt ctttacctgt
    40501 agctaatctc aagtcctgta gagcataaat atcctcatct tctatttcta caactaaatt
    40561 atcatcttga aactcaactg gaaatacatt atattttttt gcaagttttt ctggtattaa
    40621 cattggcaaa ctgctttcct ctaatataat cttaatcacc ctttatatac tttaatttat
    40681 taggtatatt catttttttc atagagatat tttcttcagt ttttatgctt attttcattg
    40741 gataattggt ttgtatgcta tctaaatatt tactaccttt atctacataa ttagatagtt
    40801 tctccttatc tccaatgcac tttatttcat atggttgtgc tacaggaact ccatttatat
    40861 ttatatggct tcctgcaagt acaacttctg aatattgatt aattctttga ccatttattt
    40921 ctatgtattt tcctccgttt acttttaatt catttataac ttttacaaga atcttattat
    40981 agtctatact attagctata ttccctgttt tttcatctat agcatctata cttaatatta
    41041 tcccactacc ctttacatct gaatatgata gactatctct aagtgtttct atttctgata
    41101 tttcttcaga atttttttga ttttgtttca ttgaattaat ttctttatct aacttgtctt
    41161 tctctttggt taattctttt atagattttc ttgtcatttt tatttctttt cttattgact
    41221 tgtctttgct tgtataaact gtttcttcat tgctataatc tctaaatatg gttccaacaa
    41281 gtatacctaa aatagtactt gctagtatta taaacacata ttgttttttc atactgtatt
    41341 gctccttaca aatttatttt tatatgataa ttttctttaa ttaaatatta aacatttaca
    41401 tatgcttatt atatcaaagt tatatattaa aattcatctt tagtatataa tatcatacat
    41461 tgaactccta tcactaattt accaatatca agtatgcatt tttagatgtt cttaaaatta
    41521 tataaacttt caataaacat tgttgtgata ttataaaaaa acataaatta ggaaaggaaa
    41581 taataattat gaaaaacaaa taatggcttt ggagattatt aatatcattt tttagcaaaa
    41641 aaagtaaaat ggcatagcct caaagctaca ccaatttact aaaaattata ttattactaa
    41701 cgttaatttt aaacatatgc gtttataagt tttcctcata ttttaaaatt cttttaatta
    41761 acttatctct taatttccct acttcatcaa atctcatatt aggactatag taactttcta
    41821 taatatcatg tttagacttg gctctcttaa gatttagtac tgcccaacaa attaaatcat
    41881 ctaaaacttt ttcatcaaat ttaatatctt cttcatattt aagtagtttt tctctattta
    41941 aaaactgatt taaatcaatt gtatcttctt ctttaaaagt cgtacttata gttatgccta
    42001 tatctaaatc agttaatagt acagtttcaa ttttctctgg aataagtgga taatgataaa
    42061 cttctacatt taaacctttt tcaatagctt tcttatatac tttgtttaat aatgtagttt
    42121 tcccagttcc tatttctcca tctaaataat agactttctt tacatctttt aaaatgtttt
    42181 ctgtataatc taaacaccct acaggagtta tagctgaacc aaataaatgc ttttctcttt
    42241 ttagatttcc tgtgctttta actccatcaa ataacctttt tataaattct tctgtgacca
    42301 aatttacttt tccataatcc atacaatcag aatatttttc ttctatgtct ctaaagattg
    42361 gttctgctga ttttaaaaac ttaaatgctc ttttaaatga attactaata tctttatcat
    42421 aaactgatat ttcttgttta ttcttttcta attcttctgt attccagtaa tcacctaaat
    42481 taattatctc atccaaagct ccaggtagct ttgggtccat agtatgtggg gcagttgcat
    42541 ccataagtac cacgcctaat ttctttataa ctaaaccatc caacgaactt gggtcagaag
    42601 gacaatgata taaatcaata tcatatcctc tatgcaaaaa ctctttataa atttttttca
    42661 taagtgagga ttttcctact ccaggtccac cctttaaaca aaaaactctt tttacatttt
    42721 caggaattat atagtcaaaa aaagaatatg agccttgtga tgtatttcca cccgggaatg
    42781 ccttctttac ctttccttcc atattagcgc ctcctcataa tttacaatat ctcttaatta
    42841 agatattcat attataagaa ttttattaca gctttctgat tttgataaat ttaaaactta
    42901 ccatctaata ctaataacag gttaatttta tctaattatt atagattctc atactgttcc
    42961 ttattctatc tataaataca atttaagtgt ccatattgaa atatttgtat tgtaatacag
    43021 ctggatatta cttaaatcca attgtttcca ttataatttt atgttaaaat aatattacaa
    43081 aatacatctg tttttcttca taaacgggtg aaattcccta tcggcggtaa aagcccgcga
    43141 gccttatggc ataatttggt catattccaa agccgacagt aaaatctgga tggtagaaga
    43201 aaatagtata tgagtacctt tatgtaattt tacatgagta atctatacaa atccttcaac
    43261 taccgtattt attcatgaaa ttagacacat tcaaggtacc taatatacag gtgctttttt
    43321 tgttgtttat tttacaatta tatcgtactt ataaaatcta ttaagattgg agtgttatca
    43381 tgaaacaaaa atggatagta ttgattatca tctgtattgg tgtatttatg tctactcttg
    43441 atggaagtat actaaatatc gcaaatccta caattgctgc tgactttaaa attaacatgt
    43501 cacaaattca gtgggttgta acagcttata tgcttgttgt aacagctact atgttatttt
    43561 tcggaaaact tggcgataaa gtaggttcaa atcgtctata cacattagga ttttttatat
    43621 ttacaatagg ttcttttctg tgtagtatgt caaacaattt atcaacttta atttcttcaa
    43681 gaatctttca ggcagttgga gcaagtattt taatggctac tgggcttggt atagtttcca
    43741 atgcatttcc agcaaatgaa aaaggaaaag ctataggaat cactggagct gtagttggta
    43801 taggaaatat gagtggtcct gtaattggag gtataatttt agaacatttt ggatggcctt
    43861 ctatttttat tatcaatata cctattggta ttatagcagt ctttcttggc attaaatttc
    43921 tgcctaaacc tgttttggat gaacaaaaca agagctttga tattccaggt cttctacttt
    43981 tcgcatcttg cactacgctt atattacttg caatgaatga gaaaggtaat acaagattgt
    44041 atttaggtat aacagcactt ataatcttct tattgttggc attaagagaa gtaaaatttg
    44101 aacaaagctt tattgaccta cctctattta aaaatagaaa ctttactgta ggcaatatca
    44161 ttggagtagc ttgttatttt cctcaaatgg cagtatcttt tctacttcca ttttatttag
    44221 aacaattaaa aaatttatct cctatgatgg ctggttatgt aatgactgta catccactta
    44281 ttatggtact tatagcacct attgcaggtt cactttctga taaacacggt gcaaaaaaca
    44341 ttctaacagc atctttttca tttatgacca tctcactagt tggaatggca cttttaaaag
    44401 cagattctcc attgtatctt ttaattgtat gtttagttat ttttggactt gggctaggag
    44461 catttagttc accaaacaat agtagtattt tagcagatgt tcctcctcaa aaacagggat
    44521 acggaggcag ttttcttgca actattcgta atttatcatt tgctcttgga acagcatttt
    44581 ttagtagttt ttttgcacaa agtcttacat acaatcaaaa gtttaaaagt cacacatcag
    44641 cctatgttat agctagcaat cagtcttatt ggattgcagc atcagtatgt tttatagggc
    44701 ttatactaac tgttttcttt atgagaaaaa cagataaatc tatttcttaa atgctattta
    44761 ttgctgacta cataagtcaa taatttttta gttgaactaa tttatactaa ttttcccata
    44821 ccttactaaa atttattagt atttagcaaa attactgata tttattgttt ataaacaata
    44881 aggatgccaa aaaaagttca ttaaaactat tttaaggcat cctatatttt gctttaatat
    44941 taatataatt aaaactaact attattacat ttattattca aataaatctt atgtcaatat
    45001 ttaacacttt aaatttaatc tactgttatt tcatatccat gttgattgta ttgatttaca
    45061 atctcttccc ataattcttc aacaccagtc ttttttagtg aagaaacagg aattactttt
    45121 tcactacttt ccatttgcaa tttttttctt attatactta tgtgtttttg atattgtcct
    45181 ctagatattt tatctgcctt agttgcaata actacacagt tatatccaaa gtgctttatc
    45241 cattcataca taagcttatc atctgctgta ggctcatgtc taatatctac aagtaggaat
    45301 atagaacata actcttgtct actttctaga tatctttcca ttatacctcc ccacttttct
    45361 ttttcagact tagctatctt tgcatatcca tagcctggaa ggtctacaaa ataaaattca
    45421 ttatttatta gataaaaatt tatagttcta gtttttcctg gtgtttgact ggttctagcg
    45481 aagtttcttc tgttaagcaa tgtatttatt attgatgatt ttccaacatt tgacctacca
    45541 gccaatgcta tctctgggat tccttctgct ggatactgtg atttattcac agcactcata
    45601 gttatctctg aacttctaat tttcattatt ttcaccactc tttaataaag cttgttctaa
    45661 tacttcatcc atatgttcta caagcacaaa ctccattttt tcttttacat tttctggtat
    45721 ttcatctaaa tcagcttcac attctttagg aattaatact tttgttatac cagctctatg
    45781 agctgctaat aacttttctt taactcctcc tactgctaag actctacctc ttaaagttat
    45841 ctctcctgtc attgctatat ttccaggcac aggtctttta gtaagtgctg agattactgc
    45901 aagagccata gttataccag ctgatggtcc atcttttgga acagcacctt ctggaatgtg
    45961 tatatgaata tcattcgtct tataaaattc agggtctata tcaaacttgt ccactattga
    46021 ccttatataa gagatacctg tcttcgcaga ttccttcata acatctccta attttccagt
    46081 taatacaatt tctcctttac ctttaagtac gtttacttct acttcaagtg taactccacc
    46141 aacttctgtc catgcaagac catttactaa tcctatttga gggttaactt ctgcaagttg
    46201 atacttaaac atgtcttttc caagatatgt ctctaggtca gacttattta taacaacctc
    46261 ttcaagagtt gggtcttcaa cgtatttttt ggcaaccttt ctacaaatct taccaatagt
    46321 tctttctagt gttcttacac cagcttctct tgtataatgg ttgattatac ttcttaaagt
    46381 ttcatcatct atttttataa agttttcttt taaagcatgt tctttaattt gttttggaag
    46441 taggtatttt tttgctatat ttaatttttc ttcttctata tatccagata cttctattac
    46501 ttccattcta tctaataatg gtcttggtat attacttaga ctatttgctg ttgtaacaaa
    46561 tagtattttt gacaaatcaa aaggtatttc taagtaatgg tccacaaaat ccttattttg
    46621 ctctgggtct aatacttcta gcattgctga agctgggtca cctttataat ctgctgccat
    46681 cttatctatc tcatcaaata agaatacagg attttttgtt tgggcttctt ttaccccatt
    46741 aattattctt cctggaattg aacctacata agttcttcta tgacctctta tttctgcttc
    46801 atctctaact ccacccaaag atattcttac aaattttcta tttaatgctc tggcgattga
    46861 ttttactata gatgtctttc ctgttcctgg aggaccaact agacatatta taggcccttt
    46921 aagtgactta gcaagagttc ttatagctag atactctagt attctctcct taactttttc
    46981 taatccataa tggtcttcat ctaatatatc ttttgcctta gttatatcta atttatcttt
    47041 tgtctcttta ttccatggca atgagaatat agtatctaaa tagtttctac ttacagatac
    47101 atctggagac atagaagata tttttgaaaa tttatctatc tctttttcta ttttctcttt
    47161 agttgtctta ggtgctttta tttttttaag cttttctcta tactcatctg cttcagagtt
    47221 tatatcttct tcttcaccta attctttctg tatagctttt aattgttctc taagataata
    47281 ttctttttga accttattca tctgtttttt tactcttaaa gttattttct tttctatttt
    47341 taatatatct atttcctcta ataatataga ataaataagt tcaagtcttt ttctaatatc
    47401 aaattcttct aatatttctt gtttttggct tgattttaga tatatgtttg cagctatcgt
    47461 atctataaat ctatctacat cttctatatc agctaaagat attaatattt ctggtgatac
    47521 cctatttcca atatttatat actcttcaaa ggcatcaaat acatttctta caaatgcttc
    47581 aatttcaact tctgtttcac tatccaaatt atcactatca aatactattt cttctattac
    47641 tgctctgaaa tacccatctt cttgttctat tttctttact ctaccccttg atacaccttc
    47701 aaccaaaaca cgaactgtat ctcctggtaa ttttatcatt tgcttaactt tacagattgt
    47761 tcccacatga taaaaatcct cttctcctgg ctcatctacc tctgcttctt tctgagaagt
    47821 taaaaatata agttcttcat ccatcatagc ttggtctaaa gctttaagag atatctctct
    47881 acctatatca aaatttaata tcatatatgg aaatatagct aatcctctta gaggaattaa
    47941 tggtaattca tgatctattt tagtataatt ttgttccatc aacattactc cttttctagt
    48001 ctaattgctt tgcttttaat attatatatt tgaacaagtt aattttcaac attaatgata
    48061 aattcttaga atactatcat actatattat ctttttatta tgatataata ttaatattag
    48121 tatacttaga tgttatttat cttttggagg tttctattat gttgaaattg tttttaacct
    48181 ttttaaaaat tggtgcgttt acatttggtg gtggatacgc tatggttcct cttatacaag
    48241 atgaacttgt aaacaaacaa aaacttttag agcaggaaga atttattgat tatttatcca
    48301 tagctcaaag ttatcctgga gtactggcag ttaatatatc tgtattatta ggatataaac
    48361 tttatggtat accaggagtt cttatatgta cattaggctc tgctttacca tccttttgta
    48421 tagtcttagt cttatcgtat ctatacttta aaaattcatc atctaaaatt ttagatggat
    48481 tttttaaagg agttgcgcct gttgtaatag ctcttatatt gtattctttt acgagcatgt
    48541 tcaagaaact accaaagtct aaaactaaca tactactatt aattatagca gttttatctg
    48601 ttggtgtatt caatataagc cctatttatt taataattgg aggaggtgta tatagtctat
    48661 gtcagaaata atactactct tcttaatatt ccttaaaata ggggcattta gttttggtgg
    48721 cggttatgcc atgctaccat ttatccagca agaatttata tctaaatatc actttataac
    48781 taatcaagag tttttggatt tacttgctat atcacaatct acaccaggtc ctgtagcaat
    48841 aaatagtgct acatttgtag gatttaagac tgctggcttc tttggttctc tagctgcaac
    48901 tattggtgtt acaatttttg cattaatagg tctaactatt atatcaaagt tattttctaa
    48961 atttaaaaat aataaaaagg tagaaaactt attgacagtt cttagaccaa ttactctagg
    49021 attcatatta tcagcagctt tttcatctgc caaagaagtt aattgggact tatatggtat
    49081 aattgcattt atagcatcat tttatctttt atataaagga aaaattggtt ccattgcaat
    49141 tgtattcgtc tttggtattc taggtatatt actcacattt ttataataat gatacctatt
    49201 ttatatttag catattaaca taaaaaaagg agcttttaaa gctccttttc atcatcttat
    49261 gcactttcct cttgatcctt aagtactatg ataggattta ctgagtcttc gttcacagat
    49321 ttctctgtta ctataacctt ctttatatta tctctagatg gtacttcaaa catagtttcc
    49381 atcattacgc tttcaactat acttctaagt cctctagctc ctgtatttct ttctatggcc
    49441 tttttagcga ttgcacgaag agcaccttct tcaaattcta gctcaacatc atctaactcc
    49501 aataactttt tatactgttt tactagagca tttttaggtt cctgtaatat ctgcattaat
    49561 gcatcttcat ccaacaactc taaagtagct aaaactggta ttcttcctat aaactctggt
    49621 attataccat attttaataa atcctctgga agtacttttt catatagctt ccctaaatct
    49681 aattcttttt tactttctat tttagctcca aaacctagtg ttttatctcc accacgtttt
    49741 tgaattatct tctctaatcc atcaaaagct ccacctaata taaataatac attagtagta
    49801 tctatcttta aaaattcttg atgaggatgt tttcttcctc cttgtggtgg aacatttgca
    49861 acagtacctt ctaatatttt tagaagtgct tgttgaacac cttctccact aacatctcta
    49921 gttatagatg ggttttcaga ttttcttgca atcttatcta tctcatctat atatattata
    49981 cctctttcag ctttttctat atcaaaatca gcagcttgaa taagttttaa aagtatattt
    50041 tcaacgtctt ctccaacata tccagcttca gtcaatgatg tagcatctgc cattgcaaaa
    50101 ggtacattta gagttcttgc tagagtttga gcaagtaatg tctttccaga acctgtaggt
    50161 cctaataaaa gtatattact cttttgaatt tctatatcct tactactaga ttttttactg
    50221 tatattctct tataatgatt ataaaccgca actgataaag cttttttagc tttttcttga
    50281 cctattacat aatcatttag aatctccatc atttcctttg gttttggtaa agatgtagta
    50341 tcctcatcta tagtatcttc tatctcttct tgaataattt cgtcacaaag ttcaacacac
    50401 tcgtcacaaa tatatacatt tggacctgca attaatcttc ttacttgatc ttgattttta
    50461 ccgcagaatg aacactttaa ttgtcgtttt tcttcatatt tagacatatt aacacctctc
    50521 tctatctacg gtctctttgt aaatacttca tctattaaac catattcttt ggcttctagt
    50581 gcactcatga agttatcacg ttcagtatcc attttaattt tttctaatgg ctgaccagtt
    50641 ctttcagata atatctcatt taaagtttct tttattttta aaattctctt tgcatgaatt
    50701 tctatatctg ttgcttgacc ttgagctcca cctaatggtt gatgtatcat tatttcacta
    50761 tttggtagtg ctagtctttt tccttttgct cctgctgcca acaagaatgc tcccatagaa
    50821 gcagccatac ctatacatat agtacttaca tctggtttga tgtattgcat agtatcatat
    50881 atagccattc cagaagttat acttcctcct ggagaattta tatataaatg tatatctttg
    50941 tctgggtctt cagcttctaa aaataatagc tgtgctacta taagccctgc tgtggcatcg
    51001 ttaacttgat ctcctaagaa gattattctg tcttttaata gtctagaaaa aatatcataa
    51061 gatctttctc ctcttcctgt ttgttcaaca actacaggta ctaatgccat ggtttcatac
    51121 cccctttatt ctatataatt tacagtagct ttttttaagc tactgtaaat tattatacgc
    51181 atttaactaa attatatttg cacatcatta tatactaaac atttcataac gtcaactata
    51241 ttagttagcg tttattttat taagctattg ttgcattatc aactaataaa tctattgttt
    51301 ttcttatttt tatttgacct tttatatctt ctttgtcggc atctcttaaa gaagcttcta
    51361 ttttttctac ttccatattg taagcagaag ccattttttc taactcagcc ttaaattctt
    51421 cttctgttgc ttcaattcct tcagctttag ttattgcttc taatactaaa gaagacttaa
    51481 ctaatttttt agcatcttct tttctctctt ctcttaattc ttccatagtt ctaccagtca
    51541 tctctagtaa ttgttgtaat ccaaatcctt gatattgtaa ttggtagtta agttcattta
    51601 acatattatc tatttgatgt tgtatcataa cttctggtat ttctatttct gtattttcag
    51661 caactttttc tactactgaa tttctagttt ctgcatctgc tctattttta gcttcttctt
    51721 ctaacttagc tcttacatct gcttttaatt catctaaaga atcaaattca ctagtgtctt
    51781 tagcaaattc atcatcaagt gcagataatt cttttacttt tacatcattt atttttacat
    51841 taaatacaac tggttttcca gctaaatctt gtgagtgata ttcttctggg aaagtaacat
    51901 taacttctac ttcttcacca gcttttttac ctactaattg ttcttcaaat cctggtataa
    51961 atgtgtttga acctataact aagttataat tttcaccttt accaccatca aaagctacac
    52021 cattttcaaa accttcgaag tctattatag ctgtatctcc atcttctaaa gctttgtctt
    52081 ctacacttac taatctggca tttttttcaa ccatttcttg tagtttagca tcaacatttt
    52141 cgtcacttac agtattctca accttagcta tttctatacc cttgtagttt cctaattcaa
    52201 actctggttt aacttctaca ttaagaacca taaccaaccc attgtcttta cttatttctt
    52261 ctatatctaa atctggatta tctattgggt ctatgtctaa ttccttgata gcttctggat
    52321 aaacttctgg gaataatatt tctatagcat cattgtagaa tatacctttt ccatattgag
    52381 tctctataac aattcttgga gctttacctt ttctaaatcc aggtatattg tatttatttc
    52441 tgcttttatt ataagcctta tttactgctg cttcaaattt attgttatct actgttattt
    52501 ttaaagtaac tttattaccc tcttttttaa ttagttctgc tttcatcctt ctaatcctcc
    52561 tagtgatatt tatgtaatac ccgataacgg tattataatt cattctattt ataattcaac
    52621 cacttaatta tatcacataa gtttttttat ttacaagtgt tccattaata tcattgtact
    52681 tatttgataa aatttaattt tttgagcgtt tttttccatt tttttagata aatacacctt
    52741 tatatgcgta tttcttcaat ttttatgtca tcttcttcta tatccataat gacaaaactt
    52801 ttatacgata ctcctcttgg aagtgaagtg cttccaggat ttatgtaaag tacaccatct
    52861 ttaatttctc taaatggggt atgggtatga ccaaatataa ctatatcagc atcaacttca
    52921 gttgcctttt tttctaacat attagttcca tattttacac catacttatc tccatggcat
    52981 aagaatatgg ttttatttgc cacttcaaag acaacttctt cctcaacagc atcaaagtca
    53041 caattacctt taactgcaat aatacctaca ttagtcatgc tatgaatata tcttgaatca
    53101 gtaaagttat ctcctgcatg aattattagg tcacattctt tcaaatatgg tattgttttt
    53161 tccatatttt taatcatcat atgtgtgtcg cttactatgc ctattttcat tacttcacta
    53221 ccctttttat aaactcttgt ttcataagtt ttagtgcgtt tgctctatga ctgattgaat
    53281 tttttataac actaggtatt tcaccaaaag tcttatcata tccttttact ataaataagc
    53341 tatcatatcc aaaaccattt ttaccttttt cttcaaatcc tatcattcct tcacaaattc
    53401 ctcttactac aaattctttt ccatcaggaa aaactactgc tattgcagag acgaatcttg
    53461 catttctttt gctcattggt acattttgca tagcttttaa cagttttttt ctattttctt
    53521 catctgttgc atgttctcct gcatatctag ctgaataaac accaggtttt ttgcctaaag
    53581 catctacttc taagccagaa tcatctgata ttgctataag tttagtcttt tttgctattg
    53641 ttctagcttt tatcaacgca ttatgctcaa atgtttttcc atcttctact atctctatac
    53701 ctgctaaatc aacatctttt aaagagtaca ctttatattc aaaatctttt aagatttcac
    53761 ctatttcttc tagcttatga gcattattag tagcaatcac tacttcatta ccataatcca
    53821 tacccaatat ctcatctgat atttcaccta aagcttctct ttgaagcctt attaattctt
    53881 tattcccttt ttcacctaac tctaacaata aatttaaatc tgctctcgaa aaaggtttct
    53941 cttctcctgt cccctgtact tctacaaact cacacttatc agtcattatt atattcatat
    54001 ctacctgtgc tttagaatct tcttcataac ataaatctag catgtgtatt ccatttacaa
    54061 taccaacact aattgcagat acaaaatttg ttattggcat ctcttttatt gtctttgctt
    54121 tatataattt atatattgct tctgcaactg ctacaaatgc ccctgttata gatgcagttc
    54181 tagttccacc atctgcctga atcacatcac aatctaccca aatagttctt tctcctaatt
    54241 tattcaagtc tacaacagac cttattgctc ttcctattaa cctctgtatt tcttgtgttc
    54301 ttccatcaat ttttccccta gatgcatctc ttatctttct ttgttgtgtt gctcttggta
    54361 gcatagaata ttcagcattt atccatccag taccactatt tcttaaaaaa ggaggaactt
    54421 tttcttccac tgatgcagtg catataacct ttgtctctcc catttctata agaacagaac
    54481 cttctgcata ctttgtataa tctctagtta tctttacagg tcttatctgt tcattacttc
    54541 tatcataact tctggtcatt ttttatatcc tttctcatat tttttatttt ttataaattt
    54601 atttttataa tttttaattt tgtcaaatat taattattgt catttttcgt aatcttatta
    54661 gcttactgaa ctattctatc attaattata gtagttttct actaaattaa gcgacttttt
    54721 aactctctaa tacagctttt acttcatctt tcgatgataa ctttaataat tctaaaaatc
    54781 tctcttcatc tataacttta attcctaaat catttgcttt agtaagttta gaaccagctt
    54841 cttcacctgc caaaacaaat gttgtcgatt tactaacact agatgtagct tttccacctc
    54901 ttttttctat catatctttt gcatcatttc tttttaatgt aggaagtgta ccagtcaata
    54961 caattttcat cccttcaaat attttttcta ctttttcacc tgtattatcc aatgattttg
    55021 tatttactcc tacatttttt aacttgttta taacgttcat atttttgtct tccttaaaaa
    55081 actcgacaac gctgtttgcc attatacttc caaattcctc taattcttct agttgctcac
    55141 tagttgcaga aattacttca tctaaatcct taaagttata tgcaagtatc ttagctgctt
    55201 taactcctat aaatttaata cctaatccat ttataagtct ccataaatca ttttcttttg
    55261 atttttcaat tgaatttatt aaattgtcag cagatttttc gcccattctc tctaggtcga
    55321 ctacatcttc cttttttata taatataaat cagatacatc ttgaataatt ttttcattta
    55381 atagcagtgt aattatagat tctcccaatc catctatatt cattgcatcc cttgacacaa
    55441 agtgtataat tccccttctt atttgggctg ggcaagacat attgatacat tttacagcag
    55501 cctctccttc taatcttatt gttggctctg aacaaactgg acacttttct ggcattttaa
    55561 aatctatttc atctccagta cgttcttctt ttataacttc taaaacttga ggtattatgt
    55621 cccctgcttt ttgaactaat actgtatcat ttatttttat atctttttct cttatataat
    55681 cttcattgtg aagtgtagct ctacttacag tagtacctgc aagtctgact ggttcaagaa
    55741 ttgctgaagg tgttattgta ccagttctcc caacttctac tattatatct actattttag
    55801 ttttcttctt ttctgctggg aatttatatg caattgccca tctaggactt ttggctgtat
    55861 atcccatttc gtctctttgt tttatattgt ttacttttat taccatacca tctatttcgt
    55921 agtctaaatt acccctgtta tctgtccagt attcaatatg ctcaataact tcatctatac
    55981 ttttacaaac tttataactc tgacttactg aaaatcctag tttttctaag tactctagtg
    56041 attcactgtg actttctaaa tcgtattctt ctatattttc catattaaat acaaatatat
    56101 ctaatggtct ctttgctgtt agttttgggt ctaattgtct caatgaacca gctgcaagat
    56161 tccttggatt agcaaataat ggctgttctt gttcttcttg ttgttcattt acttttctaa
    56221 aattatcttt tgatatatat acttctcctc taactattag ttctttttta tcatttatct
    56281 taagaggtat gctttttact gtcattaagt tttgagaaat atcttctcct acaactccat
    56341 ctcctctagt tgctcctttt tcaaactctc cattgttata agttagacct acagaaagac
    56401 catctatttt aaattcaaca acatattcaa cattttctcc cacatattct tgaactctct
    56461 tatcaaaatc tctcaaatct tgctctgaaa aagcatttga taaactcaac ataggagttt
    56521 tatgtacaat ttgattgaac ttatctaatg gcttacctcc taccctattt gttggagaat
    56581 caattttctt tagttctgga tgttcttctt ctaaagaaat taactccttc attaacttat
    56641 cgtattcata atctgatatt tctgggctat cttgattata atacctttca ttatggtagt
    56701 ttattgtctc tataagttta ttaatttcat cttttacgct cactttttgc acctcttcat
    56761 atttttaaaa ttaaattatt ttgaaatttc cctataatta attatctcct atttatatat
    56821 tttttagtat atcacttttt tggctttaaa tttattacaa aaaaaactct tattagtatc
    56881 tttaatacga ctaataagag tttttatttt tatcaaaatt ttttattttt aatagcctct
    56941 tgatatgtct acaacattat ctacaggttt attctccatt atatagtgtt tcaaattatt
    57001 ataaaccata ttaaatgttc tctctttgtt tttatctgac acccaagaat tatgaggagt
    57061 tactatgaca ttttcgcact cccacaactt attgtccttg tttaaaggtt cactttcaaa
    57121 tacgtctaat gctacccctc taaatttctc tacacattct tctaaatctt tctgattaac
    57181 tgtatttcct ctacctacat ttataaatac agaaccatct ttcataagtt taaacatatc
    57241 tttgtttact attccatctg tactttttgt agaaggcatt gctacaacta ctatatcaca
    57301 ttcttcaaat acaatattca tatcctcagc agcaaaacac ttatcaaagt attttttact
    57361 acttccatca gtattgacac cccatatttc tacaccaaaa gcttttaatc tttttgctgc
    57421 ttctgaagat atagtacctg ttcctaaaaa tccaactctt tgtccataca attctgatac
    57481 agaaaaatcc atcttccatt ctttattttg ttgttgttta aaaaattttg cactattttt
    57541 atatatttct aaaatataca atacaatact ttcaccaata ggtacactat atccgcctct
    57601 attattagct atcttaatat ttctcttcaa tacctcttct tttggaagtt ggtctatacc
    57661 tacactagtt gtctgtatat attgtaaatt tttcatctta gaaatatcta atctctcaaa
    57721 tggattgtat gtaactagta catctgctgt atttacatcc tcattatttt caatactatc
    57781 ttcagagtaa tgtatgacat catagcctaa ttctcttatt ttatcaaatt tttcttttcc
    57841 ataatttatt gtaaataaaa ctttcatctc aaatctcctc catctaccca catttaaaat
    57901 tttatattct aaaatataat atgatactca atgtacatta gttaaaatta ctataagata
    57961 tcttaaattt acttatgttc aattgttttt cctaaagaca tagcattacg ttcttgaact
    58021 aaattttcta ttaaattatt caatgtccaa tcaatagatg tctctgttac catagctgta
    58081 aaaggtctat ttattctcac tttttttagc ccttctaaaa atgcatttac ttgtgtgctt
    58141 ggagtgttat taaatattac agacttactc ttaatcccat tttcacattc atttgatata
    58201 tttccatcta aaatgtctct tattatattc tctccatttt tatcacttaa gatgatatgg
    58261 tctcttattc cagcaaagtt acttacgttt ttaattaatg ataattcttt tttattaaag
    58321 tttacaagca taatacactt cctgttgtgt attttatcta ggttattatt atttattttt
    58381 tcaaatgaca ttttatccat cctttcattt atttatatac tttaatttac cccatacatt
    58441 taaaataatc aatttttata gttaattttt atattaatac ccaaattata tttaaatagt
    58501 tgggctatcc aaaactaata tataaaatta gaataattag attaatatct acaaatcata
    58561 acctaaagga gagataccat gaatacatta ctaaacaata aatttagcat taaaaacttt
    58621 tcaaatgctt gggttatagt acttggttgt atgttgatac aagctgttcc atttagtatt
    58681 gtagcaagta tacagcctca atttataagt tatgttgtag aaggagaagg ctttagttta
    58741 gcttcttttt ctctaatatt cactattggt actattgcct cagcaattgc atcacctttt
    58801 ataggtgtat tattttctaa agtcaatatt aagatactat atttattagg ttgtataatt
    58861 tctagtattg cttttgctac tttttctata tgtactgaac tatggcaatt ttacactgta
    58921 tcatgtattg ttcaaattgg cgctacaatt atatctgcta taggaatacc tgttttaata
    58981 agtgcttggt ttgatgaaga aagcaaagga aaagctttgg gctttgcttt tgctggtggt
    59041 tctattggta gtatatttct acaaccactt gcagttcgct tattagcaac tcaaggatac
    59101 agtcgttctt atctaatatt tggaattata gcattaatag ttggtatacc tgtaatatta
    59161 ttcatactca ggatgcctaa agatattaat gaaaaggtaa aatctaaagg taaaaaagag
    59221 aaagcatctg atacaatttc tccttcagta tggggttata cattaaaaga agctaaaaaa
    59281 attaaatatt tttggattat gactattgga tttatatttg ttggtatata tgtttcatca
    59341 ttatctgtac aatatccaac ttatcttaga aattatctaa atcctattct aataggaaca
    59401 gtaggctcca catttgcctt atttgctctc attggtaatt tatttggagg attattgttt
    59461 gataaattcg gtcaaacaaa gccacttatt atatcttttg tattggttct tatagcaact
    59521 ttatcattac tattggtaga taaatcttct acttttgcat ttgtatttgc cattttgaaa
    59581 ggtctttctg tatttgctta tatgattggt cctgcttatt taactggctc tttctttggt
    59641 caaaaggagt ttggtagcat atatggaatc gtacaattaa tttttgcagt gggatttgca
    59701 ttaggttcaa cattatttgg attgttagtt gataattttg gatacagatt ttcttggtct
    59761 attataattt tatcagttat aattgcctat actttactta ttataacttc tataggaatg
    59821 aaaaaattga ataaagaaag attagataaa ctaatgcaat aattgatttt tagatatata
    59881 aatattataa taaaaaagat ggagctttta atcataaata aaactccatc ttttttatat
    59941 tacaatatag ctaattttct cttattttta actttactat ctatatcctc atccttaact
    60001 atagtaaatg ccttagttgg acaaacattt acacatgcag gcccttctgg cgattctata
    60061 caaaaatcac acttatttgc tgtcattctt tctctaaagc aaagctttcc ttcatctaca
    60121 tcttttaatg taactatgtc tattgcacct ataggacatg ctaacataca agtcttacat
    60181 cctatacaat tttcttcatt tatttttatt gtgttaccaa ccctaactat accaccattt
    60241 ggacatgcct ttgcacaagg agcatcttca caatgtctac actgtattgg agcacttact
    60301 tcttttgtct ttatgacaga aagttttgga ttaaaattta tttcatctgg attttggtaa
    60361 aaaatatctt catctgaatg tgcaactaca catcctatca tacaagttct acatcctatg
    60421 catttatcag ggtctgctat aacaaaatag ttcatcactt agccacttcc tttcctatac
    60481 aatatgtagt gtgtaataga tgatgagatt tttctcctaa tggttctacc agatattcat
    60541 catacagttt tttaatatca ggattctcat gagattttct aattgctaaa tgttcatcat
    60601 gcacgtatgt tgcttttgtt ctattttcat aagccaattc cttatattct tctagtaaaa
    60661 tttttggttg acctccacca cttacacacc caacaggaca agtcataact tcaataaaat
    60721 ctacatctaa ttttcctttt tccaagtctt caagcactgg tattacattt tttaatccac
    60781 ttactactcc aactcttaag tctaagtctc ctattttaat agttgacttt ctaaaaccat
    60841 tttctcctct tacttgtttt acttctacat caggaatact ttctccagtt ataagctcat
    60901 atcctgttct tatagcagct tccataaccc caccagtaac accaaagata gttccagctc
    60961 cactataact acctaaagga ctatcaaatt tttcttctct taagttttta aaatcaattc
    61021 ccatgtcttt tattaaataa gctagttctc tagtagttaa tactacatct acatctctat
    61081 atccactaga atccatttct tctctatcac attcatattt tttacatgta catggcatta
    61141 tagaaacact aaatatcttt gatgcatcta cattatttat ctctgcacca taagttttaa
    61201 atattgcacc acccatctgc tgaggtgatt tacaagaaga taaatgatta gttaatttag
    61261 gataattttt ttccatgaat tttacccaag ctggacaaca agatgtaaac attggaagag
    61321 ttccaccttc tgtcactctt ttaattaatt cactaccttc ttccattata gttaaatctg
    61381 ctgcaaaatt agtatcgtag actctatcaa aatttaaagc tctaagtgct gctgccattt
    61441 tcccagcacc taagtatcct aaataatatc cgaaatcttc tcctaaagca actctaactg
    61501 ctggtgcaca ttggaccata gtgaatacat ttgggtcact taaagctttc ttcaccttat
    61561 ctatatcaca tacattgtat gctgcaaata taggttcatt tatagactct ggtatctctc
    61621 tttcttgttt tttctcttgt aaaaactcaa atccttcatc tataactgag gcataagatt
    61681 tacaagtttg aacacattga ccgcacataa cacatctatc taaatttatc tcttgtggct
    61741 ttccctcttc accttcaata gcatttactg gacagacctt tgaacattct ctacatccag
    61801 tacataaatc cttatctata tttattatca taaacgtcac ctacccctgt atcctttatt
    61861 tatttgttaa caataaacta agtgcagctt gtctattctt agcttttttg tcatctattg
    61921 gagtaacaag ttttaatgct tcctgaggac atgcacttat acaagctatt ttttcattgt
    61981 ctttacataa gtcacattta taagctatct tcttattttc atctaaaatt acttgttcta
    62041 cttctttacc atcttcatat tgtggaagta agtctatagc tccaaaagga catgctagca
    62101 gacaagtttt acatcctata cacttttctt catttacaga cataatattg ttttctttaa
    62161 ctatagcttt ttgtggacat gagtttaaac aaggagcatc ttcacaatgt ctacactgta
    62221 ttggcataca gaaattgtca ccttttacta agtaaagtct aggtataaca ggtatatcaa
    62281 ctgttccaac tgtataaccc acattattat gctgattatg cattgtaaaa caagctactt
    62341 cacaagctct acaacctgta catttgtttg ggtctgctat tacaaaagag cctattttat
    62401 ttttcatatt atcccacctt tcaatttgta tatttccaac cctctagtta ttttcatcat
    62461 atatatttat atatttcact attttctcag tacttatatt tcgtttacat tttttgcaca
    62521 aattgtatgt gttattatat accttatcag tatcatcaat taatactcca cagatttcac
    62581 actttgaata tctttgctct tcttttttag tacacatata ttcattctca ctttttgata
    62641 actctctgtg gatttgcata aatattcatc cgtcttcctc ttacaaatcc aataagcgtt
    62701 atatttaatt ttttagaaag ctctattgat aaattagtcg gtgctgattt tgatactaca
    62761 ataggaattt gagtcatagc tgcttttaat atcatttcca atgatattct tccacttaca
    62821 gccacaattt tatcttttaa tgttatgtca tttaaaacac aaaatccaat agccttatcc
    62881 attgcattat gccttgctac atcttcacaa gtgactattt ttttatcaaa attaaataca
    62941 gatacgctat gtaccccacc agtattttta aataattctg atgaatttaa atttttatcc
    63001 attatactgt aaatcgtatc ataatttatt tttatattgc tctttacagg agcacatgtt
    63061 atatagtcta gtgaatttaa aaatataatt tgctcatctt gatttttttg tttctcttga
    63121 atagttactt ttgcaaaacg ttcactctca tttatctcaa attttaataa gctttttttg
    63181 ttttctatgt atccttttgt tttcaagaat cctactataa gttcctctaa attatatggg
    63241 gtacataaaa atgtatttat atatttatca tttaaaataa aactaagtgg atattctgca
    63301 attatttctt cattatctat tgatacttca tgttcattta ttttgcttac ttctacatta
    63361 aaagaattta aatatttgta gtccactaga ctataactat tttcaaaaac tttatcctta
    63421 ctattttctt gtaatttagt ttttgagtat atattgttca taaaatatta gcctttctgc
    63481 cttttataaa tcttaaatct aataaatcat tagatatttg tagctgtcat tttgtctttc
    63541 aaactttgat actcttctct tacacatttt tctgctaatt cttggtcttc aagtttttca
    63601 agtttaacag cacaatattt atactctggt gttttagata tagggtctaa atttgctatt
    63661 gtaagttcat tgcaagctcc aacccaccac tgataagtca tatatgttgc accttcctta
    63721 actctatcag taactgttgc tcttgttatt acacttcctc ttcttgaact aattctaact
    63781 aattcatcat cttcaattcc taatttttca gcatcattag aatttatttg aacacgtcct
    63841 ggttcatctt ctaatgaact aagtgttcta caattaccag tcattgttct tactgaatag
    63901 tgtccaactt ctcttacagt acataaacta aatgggtatt catcatcttc aacttccata
    63961 gggggtctcc attcagcagc gaacaaatta cctttaccat taggagtaga aaacttttga
    64021 ccttcataca gatacatagt tcctttatct tccatacttt cactcttaca aggccattga
    64081 acgcatcctt gagtttctat cttttcataa gtagcaccta agaaacttgg acataattgt
    64141 ctaagttcgt cccatatttc cttagtattt ttataattca taggatatcc cattgctgta
    64201 gaaatttcgc ttataatttg ccagtctggt tttacatctc cttgtggctc tatagctttt
    64261 ctcatcaatt ggaatcctct atctgcacat gtatatactc cctcatgttc tccccaagaa
    64321 gtagctggaa gtataacatc agcgtgaagt gctgtcttat tcataaatat atcttgaaca
    64381 attacaaatt ccaattcatc taatgcttct ctaacttctg atgcatctgg gtcactttgc
    64441 actgggtctt ctccaaatat ataataagct ttaagctttt tctcttttag tactaagtct
    64501 ggaacttgag ttaaactata accattatta ggagataatt ttacccccca agctttttca
    64561 aacttttctc ttatcttatc atcagttaca ttttgatagc caggatatac attaggaaga
    64621 gctcccatat cacaagctcc ttgaacatta ttttgtccac gtacaggtcc tattccaacg
    64681 ctttctctac caaaattacc tgtaagtaga gcaattgatg caagtccctt aactacatca
    64741 acagcttgac caaattgaca gacacccatt ccataaagta tcatagcttt tttacctttt
    64801 gcatattctc tcatagcttt tcttataagc tcttctggga ttcctgtaat cttttcagca
    64861 tatttagctg tatatggttt aacaatttct ttatactcat caaatccttg tgtatgattt
    64921 tgaacaaatt ctttattgta aagaccttct tctattaata catttccaaa agcatttact
    64981 aaaaccatgt ttgttccacc ttttataggt agatgtatat cagcaattct tgcagattca
    65041 gttactctag ggtcagtaac aattaattta gcaccatttt ttttagcttt tactattcta
    65101 tttgccacta ttggatgtga atctgctcca ttatatccaa atataaataa aacatctgca
    65161 ttttctatct ctggtataga attagacatt gcaccactac ctaatgagta agccagaccg
    65221 gctacagatg gtgcatgtca gacacgagca caatggtcaa cattattagt tcctattgta
    65281 gctctcataa atttttgcat tatatagttt gcttcattac caggtcctct tgcagaacct
    65341 gttcccataa tagaatcagg tccatatttt tctttaattt catttagtct tgaagctgta
    65401 tagtttatag cctcatccca ttcaacctct tctagtacac cttgttttct tatcattggc
    65461 ttttttagcc taggtgttag aattttaggg tcatttagaa aatcccatcc ataacgacct
    65521 tttaaacaca aactttcttg atttgttcta ccattagccg gttcagctct taatatctta
    65581 ttatctttta ctactagata taattggcat ccagctccac agtatggaca aactgttaaa
    65641 atttttttct ccatacaatt ccccccttag atttatcccc tgataagtaa aatttatctt
    65701 aaagataatg agtgttttta taatatgcaa aatcataaat attttgcaat actatctatt
    65761 aaattcaaca attttctcac aattcctctt aaatttcaaa aaaaatatgt cataataatc
    65821 tttatatttc aaccatttaa ttaaaatatt ctagttctta tgacatattt tttaatatac
    65881 tcaatatata ttctttaaac ttatttagtt ttcacttaaa acaatatttc tgccaattct
    65941 atttttcatt ctatagtgag taattacagt aaatattcca cttccaatca gaatcaaata
    66001 gtacataaat ccaccatata aaaatactgc atatcccatc aaaggttgag ggaatactga
    66061 tttgaatata gtgaaaaagg ctaattcatt agctcctaca ttcccaggtg ttggtattgg
    66121 agatattgcc atatataaaa atgcttgtaa tgtcagtata taaatatagc tataaccttg
    66181 taaattaaat gctttatata tccaaaatga aacactaaag taagcactta attgaataaa
    66241 agttactatt atagttgaaa ttaatacctt tttattcttt gcaaaaaaat ttattgcttt
    66301 actataatca tctataaaac tttctatgga ttcaatctta ttatctaaaa attttaaaaa
    66361 cttaattttt gataaatgct ttatagtaat tctcataaaa tattttattt ttttaggatt
    66421 taaaataact aatattatca taattaagac aaatgaatta atggctatcc ctagaaacac
    66481 tagaggcata atcattttca tttgtttttc taacatagca aaattcatta aaacaagtat
    66541 tgtacaataa aaagtaacta ctatttggaa gataatagac ttattggtaa caactgcact
    66601 tgccttacta agtggcattt tacatttttt aagtacatat atctgtactg gttggcttcc
    66661 tgaagcaaaa ggagttatta aattataata aaatcccata atggctagct taaaaccaat
    66721 aaatctaata ttaactttgt gagtgctttc tataattatc ttcattacta ctccttcaag
    66781 cattatgtga cacattattg ccaaagcacc tatgaataaa aacttcttat ctaccataac
    66841 cataacattt gatagcattt taatatccaa tgttttaaac actaggtaaa ttgttatacc
    66901 tattaacaaa aataaaaatg tatactgtag taaactcttt ctaatattct ttagtctatc
    66961 cattagaaat aaccatcctt tgctcaagat ttatactaaa tactatatta ttagtataca
    67021 ctatgaatct taatatttta taacaaaata ccttacaatt ttgtcattta caaaaaatat
    67081 taatctataa attaaatttt aatatataga ttaatatttt acaaacattt tgtagatata
    67141 tataatattt tcactaaaca acacttatac ttattacacc catttatacc ctatccccca
    67201 tacagtttct attgtataaa tatcatattg ttttaatttg cttcgtatat tttttatatg
    67261 ctctgtgata gtacttatat cactttctcc atcaaaacca tataccgact catatattct
    67321 ttcttttgaa aatacttgtc ccttattttt tgctagaaat tcacatatta gatattcact
    67381 tttagtaaaa ttaatttttt taccatcaat tgaaacttct ttgcctaaaa agttaaattg
    67441 aacatttgag atagttaata aattcttttt ttctctactt tctcgcctta aatgagcagt
    67501 tatcctagcc cttaattctc ctacaccaaa aggtttggtt atatagtcat ctgcacctat
    67561 accaagaccg tacataatat cactttccat attttttgct gtcaaaaaca gtattggaca
    67621 atcaacctta tttcttatag ttttacatac ttcaaaacca tccatcttag gcatcataac
    67681 atctaatatt attagattaa aataattaaa atccatgttc atagcctttt ctacatcact
    67741 aattaccttt acttcatgtc catctctttt caacacattt tcaatcaact ttaacatatc
    67801 taactcatca tctactacta atatcttaga cataataact cctccattta tccatctaat
    67861 agcattctaa tttatatatt taataatatc tttaaaattc acattaacca taatactctc
    67921 atattatagc ttacaataat taattactat tttacaaata aaatatttta gatacaaaaa
    67981 ctttatattt caaaaacttt atattcattt tacacgtatt tacttaaata taaaaattta
    68041 tttaacaatt tattattgta atattttgaa tatataataa aattaataat aagaaaactt
    68101 tttaatactt ttaattgttt aaattggagg aaaaaattat ggatgaaaag ataacaaaaa
    68161 ataattataa tgttccattt gactatgttc gaaaaaaact caaagaatta gaccctcata
    68221 caattagtaa tttaagtaat atacctttca ataatgattt aaatagattc acactcaatt
    68281 tttttgatag acaatatatt atagactatc caagtggaga agtttggaat agtaatggta
    68341 gcctttgcaa taactttgag cttaaaatct tgatagttag atatttaatc aatgctaaag
    68401 gtattcctag aactaataaa tatgtaactt ttaaagaaat accaggaggc aatgtttatt
    68461 atccaaattt tttaaacagg actctatata ggctttcaga agtttttaca tctcaaatag
    68521 acaaatataa gttagttatg gagaaaattg gagctgaaaa agtaaacatg ggagatttag
    68581 cttataggtt tacatatatg ggtaatacat ctatgatatt tatactttgg tttggagatg
    68641 atgaatttcc tccaaattca aatatattat ttgattctaa tatagtttat tacttcaatg
    68701 cagaagattt agcagttgtt cctgatacag ctataaatgc aattttaaat aaaataaatc
    68761 aattataaat ataaataata ttataataaa gtttttgata tttagcacat ggcgagaaga
    68821 tggacgtttc aaactatatc caaatggagg tatttaccct tgtcatactg caaatgctgc
    68881 taacgtactc tgtcatatgg gatatgcatc tgacattaga atgcaaaaaa cgtttcaaca
    68941 ttttttagat acacagtata ctgatggtgg gtggcgttgc aataaattta gttttggtcg
    69001 aggtccagaa actgaatact caaatccact accaactctt aatatattaa atgcattccg
    69061 ttttagtaat tatctaaata aagaatcaaa acttgacaaa gctgtagatt ttctacttga
    69121 ccattggact attaaaaaac caatcggccc ttgtcactat ggaattggca cattatttat
    69181 gcaagttgaa tatcctttcc gtaattataa cctattcctt tatgtctacg ttttatcatt
    69241 ttataatcgt gcaaaaaagg ataatagatt tttagaagca ttgaagatac ttgaatctaa
    69301 aatgataggt aataaaattg tcgttgaacg tgtagttcca aaactatcca aattatcttt
    69361 ttgtaaaaaa ggcgagtcaa gtgaaatagc cacaacacac tattacgaaa tattaaaaaa
    69421 cctagaaaaa taatagttat atatataaaa catattaaaa aatagtggct ttaaattttt
    69481 taaagtcact attctatata aatataacaa tataaaaaat atattaaact atttactctt
    69541 ttttaaaacc gttgattttc ttgctatata aaaaactatt attatagaaa taactactag
    69601 agaacctcta tttataaaga aataattctt taattcatta aatctaacat ctatattgtt
    69661 aggcatataa aacatctttt gaatataaaa tccatttaca ttaatcatac taacaaatgg
    69721 gtacatatgt aaaataaaaa atatatcagc aaatgtatat gtaattaata ttgctattgt
    69781 tgtaaatcta ttttttgtta atgttaatat cattagtgga aatgttgtat accataataa
    69841 tgtaggaaat gtctttaaaa acacatctat tggctttaca ctataaacaa aatctatttt
    69901 gtctatgtta aaacctttca ctgacgtaaa tgtatatact attgtaattg aaattaataa
    69961 taatacagta tatatagcta atataacaca ccatctaaat actataaatt gattatattt
    70021 ttttttatta tataaagtaa gtatctcgtt tatattaccc gaataatctt ttgaaaacac
    70081 ataaattatt gtgattgctg acattattgg tataaaaaca tctgatatct ttataattcc
    70141 taaccatcct gctatagaat atgtatccat tataggtaca tcattataaa atattaactc
    70201 attataatct aatatgcctg taataaatat gcataagata gaaataatta caaatattaa
    70261 cacatgttta agctctattt ttttaagctc aaattttatt aactccaata tacacattta
    70321 ttttaactcc ttatgtaaaa agtttatata agcatcttgt aaagttgtat ctatccttaa
    70381 gctatcttta agtttctctg tatttttacc tatatacttt acttgcacac catctttaac
    70441 tctcctataa tcaataatat caatattacg ttctaaatat tcaaattcat cattagaaac
    70501 tactaccgaa tacacctcaa ccatatcaat aaacttatta attgtaccat catataatat
    70561 tttgccttga tttaatataa ttaatttgtc acagttaaat tgtatgtctt ctactatgtg
    70621 agttgaaatt aatactatag aatttttact tatttctggt aacaatcttc taaattcatt
    70681 cctttgctct ggatcaagac caactgtagg ttcgtccata actattaact tagaatcacc
    70741 tattaaagcc tgtgctatac ctagtcgtct ctttacacca cctgagtatg tacctatttt
    70801 tttatttata aacttgtcca gattaacttt tgatactact ttttgtatat gtttctttaa
    70861 atcattctta gatacacctc tcattttagc tacaaattct aagtattctt gcccatttat
    70921 attattatac atatcaaaat cttgaggtac atatcctaca tttgccttga ttttctcatt
    70981 gtttttgcta tactttatat tatttaattc tatctctcca attgaagttt cataaagagt
    71041 cactaataac ctcattaatg ttgattttcc agcaccatta ggacctaata atgcaactac
    71101 tccatctgtt agggttaaat ttatattatc caaagctttt ttatttttgt aattaaaatt
    71161 tagatttctt atttctaact tgtttatcat attaacctcc tttattattt atctattata
    71221 aggatatttc ctgaaagcca atgataaata gttatgctaa ttttctctcc ctttgagtct
    71281 tcatataaaa attcattgct aggtaagtca gcaactaata tcatattaat tttttttctt
    71341 tttattgatt ccataacatt atctacttca tctacatatt ttttagcatc tacagatgct
    71401 ttgctatcac ctaatatttc atttcttgtt tcaattaaaa atttaatttt ttcctctata
    71461 tccatattta cattactatc tgatggatag attattttta tatcatcttt tacctcttct
    71521 ttaaactcac ctgcatatat tgcaatatca tttgactttc cttcaaatat ataatctttt
    71581 tttaaaaaat tactagtctt attcagtaaa ggtaaatttg aatagacatt acttttagaa
    71641 cttaaattta ttttataagc catataactt gattgattta cttttgggta ccacgctaaa
    71701 gaacctggtg gaagcataat atcatcttta gtagctatat atttattttg attccaagat
    71761 gtcaacacat taatatagcc ttcatactct atatctaatg tcacctcgtc attaggctct
    71821 aaactttcct ttaaattaac ttcaattaaa tccttttttt tgttaaattt tatattttcc
    71881 gaatttactt ttatatattt tatatcaaat atttcatcta aaatcatatt aatatttgtt
    71941 aactcttcat ttgatgtgtt taataaaaca attctatctt ttatatttga cttgctttta
    72001 aagtcaatct tcatatcatg cgattttatt ttaatatcac taatattaga tttctttaaa
    72061 tactctccat aactacgctc ctcatctcta tatgttgaca tatctattga tatataattt
    72121 aatccaataa ataaaatact gtacactact ataactatta atgatttaat ctgtttcttt
    72181 ctaatatcat ttaatatcag atatgctact attattaaag taattgcaaa tagtgtaggt
    72241 ataattttat ctataacata tgctgaatta ttaactttcc ctacaaaatc agaatagtaa
    72301 gcatatgatt gatcttcaaa tatgttaagt gatttaaata atgctttaaa aaatggttct
    72361 ttaatatcaa taactctatc caacatctta gttgatgtta aatataaaaa tactgatgat
    72421 aaggtaatct ttagtattaa attatttata ataactgaaa taaatgatat cactatagat
    72481 aaaatagtaa gtggtaaaaa ccattcaaat atcaatataa atatagttga tttaatcgtt
    72541 acaattgaca atgttcttat taaacttgag tatgctatag catatataat tggtatgcaa
    72601 caaaatataa agttgtttct agttacagca acagaaatac ctaaaaaata atcaaaatta
    72661 tttctacata atatttttac agtatcataa ctttttctca tataaaaaat tacatttaac
    72721 atggttaaaa tactaattgt catacaagta tatacactca aggataagta atcattaaat
    72781 gaaattcctc tattggatat atgtgtccat cgttgtatga gatggtaatt tataataata
    72841 attgttattg caaataaaat attttttcta attattttgg ttataaagtc tgatataacc
    72901 ttaatactac tcatatttat gcccctccta gccagtcttt tgatacaacc tacaatagat
    72961 tcaactatat ttaataagtt caaatactta ccttgacatt atttttttaa agttaatatt
    73021 aattagtgaa gttaattaat ttagaaaatg ttttataatc ttactgatca ctattaacct
    73081 tcattccaat atatattaat atagcaatcc aatatataga aattattgca taaatcacat
    73141 attgctgaaa aatattaagt attttacata aaataattaa acatattatt acgaatagta
    73201 ttttttgcac agtctttcta taatgctttt tctcactttc actaagaggt ttgtttctat
    73261 gttctaaagg agctaacttg taaattgtta gtatactaat aatcattaat aatactaata
    73321 aatacttata tttatttata tctatattat tagctgaaaa aatagttatc aaataaataa
    73381 ctgcaaatgt taatgtacac tctttataat tcctagcatg ataacctcct gtgaactgtc
    73441 ttaaagtgca ataacaactt aaaaatataa ctgtatgtat aaatctatca aaaataattc
    73501 ctataaataa tgctaccaaa atattaacta tgaaataaat caaagtttca aatccatatc
    73561 tatatatttc aaaatcttca ctttctacaa tctcattatt aactaatata ttggcaaatt
    73621 tatatgataa tcttttaaac atatttcctc ctcaacatgt aaaacctctc ctttaataag
    73681 aagaggtcct tttattaatg ttattttttt agtttttgta aagcttgtgg ctcttttgcc
    73741 tgatgtgcta cccaagaact tgcactgttt gctgataata cagctatccc aaaacttaat
    73801 gctgagatgt ttttaagtaa gtttaacgct atttttttca ttttgtactc tcctaacttt
    73861 ttattggtat cattattttt aatataaact cattatctga gtaattaact attgtttcac
    73921 caccatattt atttactata tatttaatac tagcaagtcc tattccatgt atcttatcat
    73981 catccttact agtttgaata cgtttatcaa taagtttaat atcatttacc ttagtattta
    74041 taaattttat tattgcaaat ttatttatat atgtagcttt aacttctatt cttttttcta
    74101 tctcattatt tatatccata catgcttcaa ttgcattatc tagtgaattt gcaaatattg
    74161 aacatatatc attattttta ataaagttta atttagatat atttatgtta tcttcaattt
    74221 gaatatcata ctttttacaa atacttattt tttctgctaa aattaaatct aatgttttat
    74281 ttccagtatt tttaaaatgt tcaaattcac ttatctgaaa ctctaagtta tttatatatg
    74341 atataatttc ttctttagtg tcataatttt ttatacaaat catatggttt ttcaagtcat
    74401 gataaacata ttttaatcta tcatgaactt cgtttatatt ttcataattc ctgtagtttg
    74461 tttttattct ttcatttata agttcatact ctagatttaa tttatcgtct tgtacaattt
    74521 tccctattac tattaaaagt attatacttg atgataaaat caataaaatt gcaaatataa
    74581 atataaataa gttttctgta gtaattgtat tgactcttaa attatattca aatataagta
    74641 ataagctaac tatattagat aatataggta ttcctattag tatcatatct ttaggtttaa
    74701 aatctaaaga taatttaaaa tacttaaaca atataaaacc tataaataaa aatacctttg
    74761 acataataat agcttgtatt ctaaataagt tttcatgttg tgttatgtta atattattta
    74821 atttatttat aaatactact agacctactg cagaaccttc agcaaccatt aatcctagcc
    74881 aaaacaataa actaactatt atacttttat agattttatc ttcatatgat gttatataaa
    74941 atgatattcc tattaccata catagaagaa tcttaatatt tggaaacact ttaactacat
    75001 ttatgtatgc cataaatata attataatta ttgttgtaaa tatatatctt atattagata
    75061 ttttcctctt tccaactaag tggattacta aaaaaaatat aatccaatct atagtacctg
    75121 aaactaaatt aataatattc caaaatccta cacttaaatt tgttagcata ctatgtcccc
    75181 taatatatta gttatcgcaa gcttcaagcc tttaacccta tatttactta ttggaatact
    75241 ttttccatct actataacag tacttccact cattgattct actaatttta agttaactat
    75301 atagctatta tgacatctaa aaaatccata ttcatttaat atcttttcta ttttagatat
    75361 actcatttta gtaatataca tatcatcatg tgtataaatc aatatattcg gtctatctgt
    75421 ttctatataa gtaatagaat ctattttaat tcggtctaca taatttttta catttatagt
    75481 taagtaatta tttctctttt tcatcatctc atttatacaa ggtaatacac ttttagaaat
    75541 tttttcttta tttattggct ttagtatata tctgtatgct tttacctcat aaccttcttg
    75601 cataaactct acaaatgaag taacaaatat tatttctaac ttatgatcaa actctcttat
    75661 cttcctagca gtatccatac catttattgt tttcatttgt atgtccataa ttaatatgtc
    75721 taaatcttta ggatagttat ttagtaactc ttctcctgct gaaaattcat atatgttata
    75781 atttatagga tatgaactta atatttcact taatatatct tttattttta ttcgataatg
    75841 tagttcatca tcacatattc ctatattaat cacaattctt aaacatcctt tcttatatat
    75901 ttttaataaa aatatataaa tttctattca ttttacatat tttaacatac ttctgtagta
    75961 aatagctatt tagattttaa ttttagcttt ttggacatta agtattactt tttggatttg
    76021 caatctattt tgattttcat tataatacaa ttttttaata tatattaaat atatttaggg
    76081 attttaataa aatattcctc gaaaagtttt taatatctag tttttgttaa ataaaaagta
    76141 tgcaccttcc tttttatagt aatattttaa ttatcgctat aattttgaag aatacacact
    76201 atattttaaa tattaatata aaacatatta aaaaatagtg gctttaaatt ttttaaagcc
    76261 actatttttt taaatgatgt tcctgaaaat atattaagtt agttattcta atcaatttga
    76321 agacttttgc ttctccttgc ctatatctaa cataatttca taatttaatt tacctttctt
    76381 taaatcaact cctgagttac ttctaataat cccacaatcc aacatttcgt caaatacctt
    76441 cctagataaa cctagtttct cacgtaataa tgttgatacc tttaactgac atggatattt
    76501 actaataata tgaacttgtg taaggtcatt aatattaatt tcttgtccta ctattttata
    76561 ctctggaata ccaacttctg ctccatttct atgtaaaagt tccatattca tagcatattg
    76621 cttaacaaga ttataatcgt ttgtatggaa ttgttctagt atttctggat ttaagctttt
    76681 tggattaaca cgagaatata tagttgagtt ccatgttgaa tcacaatttg aacacttgta
    76741 tattaaccat atatccaaat atttatgttg agcattaacc ctaaataaac ctgaacaaat
    76801 atattcagtc ttttttccac attttttaca atacctaatt acaggtaacc gggagatata
    76861 ttccacctcc caagtaattt ttttcataaa tacaatttcc tttctataag attactaaat
    76921 taatagaaag ttatgaaaag gtggaatata atcaagtatt tttttcaaaa caagacctcc
    76981 taattttaat aaattttaat ttcaaacata taaaaagcta ctacttctta ttagatactt
    77041 tacaaccagc tttgttagct actgtataag ttattgaaat tacttaaatt atatcatcca
    77101 cttaaaagaa actatacctc aaacactttt atcaaaagaa aatgagccag tataattata
    77161 aaactatact ggctcatcct tagatatctt ttcttttttc ttgtaataca attctttgga
    77221 tacttttcaa agataaataa tacttttccg ataaatattg caaatcatat ccaacttgat
    77281 agtcttcgta aatctgcata tttctaattg acaactcttc acgagtaggt gtattacttc
    77341 cccattcttt tttattatta gattttctag gaatatagat acattcacca tctacatatt
    77401 cctgtattaa ttcaagtaat tcttctggta atatatgtat tgctttttta tagctcattt
    77461 tgctctccta ttaaatagta atttttcatt aggaatagca aagggctatt tatatattaa
    77521 atttcatagt tgcaatagcc cttgctatgc aaaaataaag attaaatcaa acataaaatc
    77581 tcaaccctcc ttatatatca cagcgataca tataagtcta tcaacagtat aactggttgt
    77641 caatcaacac aaattattta tccatttttt aaacacattt atttagtttt tatattatat
    77701 ttattttgat aactaaaatt ttttcattat aaactatctt taaaattatt agtcaactta
    77761 aatccattat cttgatgggt ttattactga acaaggaact ccaactatac actttccaca
    77821 aatatcacat ccacctatat aagtgtattt tttttcattt atcatacaca tttcataaca
    77881 cttattccta ttaaatccat cttcttttaa agcttctttc acgcatttat tgacacattt
    77941 tttgcaacta ttattatgtt tatacaagca gtattcattt tctggtcttt tagttggctc
    78001 taattctaaa cttgtgatta tgcttcctat tcttccacaa cacccttttt ctgtaataag
    78061 catattattt aaaccaaaag ttccaagacc tgctatgaat gctacatgtc tttgtgacca
    78121 gtcacttacc aatttttcac tgtcaaaatt atacgaccca ggaatagcat atgaattagc
    78181 ccctatcttc tctagttctt cacataagaa atcatttaaa tttgaaatca acatattagt
    78241 ttctatgtac gctcttgccc atatttcaga acattcaaac cctccaatat tactattatt
    78301 tacactttca tcaaaaggta taaaatatgt aattatagtt tttccatttt ccagaaaatc
    78361 ttttggcata gcatgagatg ttcctacaac actttttagc ttctgaaaca tatcatcttc
    78421 agcagatgca taagcaaaca aaagttcttg ccactttgta gttatattat ttgatttatg
    78481 ataatttttt acaaagttgt tcattgatat ttcaatctta tttttcatag tatcacccct
    78541 agataattct atatttccaa tttaatgtta ttattttata ttatataata gtattttata
    78601 atatgcgcac taattaatat taaaactatg ttcatcaatc attcttaaaa aagctcctaa
    78661 tatcaatacg atattagaag ccttttctta tctaatctaa tttattgcaa ttcctgcact
    78721 tgcatatcct gctacagtat taactaatga aagacctgaa gctgttgcag taaatactag
    78781 taagaatcga gtttgtgctg ttgctgctat atttaatcct gttacaattc cactagaaat
    78841 tgaaccaact gataatatac ctgtaagtgg tggagctagt gtaactgtcg ctcctggtac
    78901 agctgtaaat gagttatttg gtgcagtaga ttggtaaagt gttgctgtaa ttgtaattgt
    78961 tgaaccaaca agtgaaagtg ctgctgttgt actgaagtat gctgaaatag atgttattgt
    79021 tccatctctt ggcattgaaa atgcaaagtt agtcaatgtt cctgctgcgt ttgtaaggtc
    79081 tattactcca ccaactatac ttaatcctgg agctgaacta ccaaatccaa caaatccagg
    79141 tgtacctact aatcctccag ctatagttgt aagtgatagt ggtatacctg atgcaaaagg
    79201 tattattgca ctagcacctg ttgctcctgt tgctcctgtt gggcctgttg ggcctgttgc
    79261 tcctgtaact cctgttgccc ctgttgctcc tgttggacct gttgctccat ctgcccctgt
    79321 tgctcctgtt gctcctgttg gacctgttgc tccatctgct cctgttgccc ctgttgctcc
    79381 tgttggacct gttgctcctg ttgctcctgc cactcctgtt gctcctgttg ctcctgttgg
    79441 acctgttgct ccatctgctc ctgttgcccc tgttgctcct gttggacctg ttgctccatc
    79501 tgctcctgta tttcctgttg ctcctgttgc tcctgttgga cctgctactc catctgctcc
    79561 tgtatttcct gttgctcctg ttggacctgt tgctccatct gctcctgttg gacctgtcgc
    79621 tcctgttgcc cctgttgctc ctgttattcc tactcctgtt gggcctgttg ctcctgttgg
    79681 acctgttgct ccaggtgttc ctgctgctcc tgttgctcct gttgggccta ctaatccatt
    79741 tgctcctgtt gcccctgttg ctcctgttgg acctgttact cctgttgctc cgtctgctcc
    79801 tgttgcccct gttgctcctg ttgctcctgt tactcctact cctgttgggc ctgttgctcc
    79861 tgttggacct gttgctccag gtgttcctgt tgcccctgtt ggacctatta atcctgttgc
    79921 ccctgttatc cctattcctg ttgctcctgt tggacctgtt gggcctgtta ttcctattcc
    79981 tgttgctcct gttgctcctg ttgggcctgt tactccatct gctcctgttg cccctgttgg
    80041 gcctgttggg cctgttactc ctgttgctcc atctgcccct gttgctcctg ttgctcctgt
    80101 tggacctgtt attcctattc ctgttgctcc tattgcccct gttggacctg ttgctccagg
    80161 tgttcctgtc gctcctgttg gacctattaa tcctgttgct cctgttactc ctactcctgt
    80221 tgctcctgtt gggcctgttg gacctgttac tccaaatcct gttgcccctg ttgctcctgt
    80281 tggacctgtt attccatctg ctcctgttgc tcctgttgga cctgttggac ctgttactcc
    80341 atctgctcct gttgctcctg tcgctcctgt tgggcctgtt ggacctgtta ctccaaaccc
    80401 tatagctcct gtcgctcctg ttgggcctgt tgcccctgtt gctcctgttg gacctcttaa
    80461 tcctgttgct cctgtattcc ctgtatttcc tgttggacca gtcggaccgg ttggtcctgt
    80521 tgggcctgtt gcccctactc ctggacctgt tggacccgtt ggacctgttg ggccggttct
    80581 acctcttgga cccattgggc ctgttggacc tacacatgat ggtggacagc aatgatggca
    80641 atcacagcta ttataatcat cacgaccatt gttacaatca tcatatttat catagccatt
    80701 gttgtaatca ttatcatcaa atggtccaaa atatttattt ctactcatta ttaaaagcac
    80761 ctcctgatat atttgagctt ttaagctcta tatataatat gtcaaattta gtatgattgt
    80821 gacctatcaa ctatttttaa atttactaaa ataattttca ttgtgcaaaa cagcactatc
    80881 gttaggtttg atttcttttg ttttttcatg ataataaata gctttatctg attctcctaa
    80941 cctgtcataa cagacactta attgtataga tggtatatat ccataacaat catttgactt
    81001 aaagcctcca ttagtatcat tcttatctct tgttaatgct accttatacc aaaaaatggc
    81061 ttctttatat ttttgtctat caaacatatg ctttcctatg tcacaacaaa tttctgctct
    81121 tggctcatca aattcgaaac ttctaaacaa tgaatataag gcactttttt catcattaat
    81181 taagtaataa catgtggcta aatctctgca agcactgata caatcctcaa tccatcctct
    81241 tgatgagtct aaaaacttag taaaaccttc tattgcttct ttatacctag cattatagta
    81301 caactctcta gaataataga attggtgtct tggctccaat gtttttcctt ctgaaatcat
    81361 tttttcaaaa attctaagat ttcttagagg gtcctgtcta tgaagctttt tatgagatat
    81421 tgcaatgtca gaataaaata cctctccaaa aagaggtact acttcatgaa tagggtcaac
    81481 ccatttatga ttagaacttc ttttaaacaa tcgttctcta taatatgaga gagttgggtt
    81541 accattttca tcaaaggata cattgtattt tgccataaca atatcaatgg aagtatccaa
    81601 gctttcttta atctttaata atttttctct atcagcttct aaaattatgt catctgcatc
    81661 aagccacata gtatagtctt tagaagcttt agaaaatgaa aaatttcttg cagcagagaa
    81721 atcatctatc cattcgaaat cgtacaccat gtctgtatat tttgagacta tttcttttgt
    81781 ggaatctgta gaaccggtat ctacaattat aatttcgtct actatatcct ttacacattc
    81841 taagcatctg cctataactt cttcctcatt cttaacaatc atgcacaaac ttattgtaat
    81901 cataatgtac aactcctttg tcttctatat attgcagaca taagtaatat atggtatttt
    81961 ctcttgtttt gttattaaat ttataaaaac ttttgacgac agaaagttac taaagaacct
    82021 tatcttttat gtatttttta tagtagaatt tattaaactt gaaatttggt aataattgtc
    82081 gaaatgataa aaccatattt aatttcatac aaaaaagagt gtcccataaa ctaaaaagtt
    82141 cattttgaga cactcttttt taatattata tatatatttg taaaacagac attttaatat
    82201 gatactttga tactttattc attcctattc attatataat caatcagccc gtactcttta
    82261 gcctctagtg cagtcataaa attatctcta tctgtatctc tcctaatatc ttctattgat
    82321 ttacctgtat tttcagaaag aattttatct aatcgttctt ttattttcaa tatattatct
    82381 acagctattt ttacatctgt tgcttgacct ttagctcctc ccattggctg atgaatcata
    82441 atctctgaat tgggtaaagc acatcttttt ccatgtgttc ctcctgcaag taaaaaagca
    82501 ctcatgcttg cagccatacc aatacaaata gtcgatacat cacatctgac ataattcata
    82561 gtatcatata tagcaaatcc tgatgtagca gagccaccag ggctatttat atatataatt
    82621 atatctgaat ctgggtcttc tgattctaaa aacagtaatt gagctactac taaacttgca
    82681 atagcatcat taatttcttc tcctataaat ataattctat cttttaataa ttttgaatat
    82741 atatcataag acctttcccc ttgacctgtt tgttcaatta catgtggcac taaactcatg
    82801 ctactttcac ctcacaatta atattaaagt taagataaga attgatttca tctcttcttt
    82861 gtttataatt catatttgca taagaaatac atttttcact ttgaatttga tgatttagat
    82921 ttaaaacaaa tctctgttga ataggataaa attcatcttt atttctatat acttgtggag
    82981 attctttata taaatttcta aatgctagtg taaaagattg atgtgtagaa tatcctactg
    83041 taatagctat gtctataata tatttgtctg taaatataag ttgtctagct gcttcagtaa
    83101 gtctcctcct ctgtatgtat tgatggatag tacatcctac aacatttgta aacattctgt
    83161 gtaaatggta ttttgaataa ttagcaatat aagctatttt atctaaattt agattttctg
    83221 taagattttc ttctatataa tcaattatct ccataataac atctgtattt gttttcaact
    83281 ctatcctctc cttttaagta ttataaccta tgcaaaaagt tttttcttaa tataaattgc
    83341 tatcttaatt tagtgtatag caataaagta tcgataaaaa aatatcaggt atttttatac
    83401 aaaaatatta atatatattt cttttaaagt ttaaacttaa ttacatctat tatatgtaga
    83461 ttgctacatg ttttatctat gtaccttgat tcatatgtat tattttgctg agtattttta
    83521 cacctttttc aatttcatca aaactaagat gagcataacc tagtataatt tcatggtcat
    83581 attctaatat attctcaatt gcatattgtt gtataggata aacttttata cctgcttcaa
    83641 aaattttatg aattaaactt tccgtaaatt taacattata gaaatgagca actatatgaa
    83701 gccctgctgc ttcacctttt attttaaatt catttttaaa ttccgtgttt aaaactttta
    83761 tgaggtactt acgttttcta ttgtacaact tcttcattct aaatatgtac ttctctaaac
    83821 ctccatttcc aataaattca gctaatacat gttgcaatat tgtttctgta tgaacatcag
    83881 agtacatttt taaggtttta tagctttcta aaatattgtc tggtaataac ataaatccaa
    83941 cacgaatagc tggagataat attttactaa aagaacctat gtaaattact ttatttgggc
    84001 taagttcata aagagaacta attggttgac cctcatatct aaattcacta tcataatcat
    84061 cttcaattat atagtaatca ttctctgttg cacatttaat aagctctagt cttctttgaa
    84121 taggtaaaat ccctcctaat gggtattgat gagaaggtgt agtataaaca aaagaaatcc
    84181 cctttattga ttttattaag ttggtattca ttcccttatc atctacttta attccaacaa
    84241 ctgaatatcc aatagatgaa ataaccttta ataagccttt atgaataggg tcttctacag
    84301 caaccttttt attacttttg tataaaagct gtgaaattaa agataaacct tgtgttgaac
    84361 cagaaacaat cataatgttt ttgggattac atctaattcc tctagtacga aataaatact
    84421 tagatatttc cactcttaaa acccatacac cagctgtact tccatatctg aaatccgaat
    84481 ctgataaatc atacagtatt tgtttatata gctttgaaag ttctttgcgt ggaaatagtt
    84541 ttaattctgg aactcctgaa cgaaaatcta tataattttt ttgtttatta gtatgtaaat
    84601 ctttttcatc tctaaaagta tcatttaact taaaatcaac tttatgccct gatattcctt
    84661 tagctacaat tgttccatat ccattccttg tttccaaata tccttctgca attaattgat
    84721 tatatgcatc taaaactgta ttacgagata cagatagttc ttttgataaa gtcctagatg
    84781 atggcagttt ttgctcaaac tttaagcttc catccagaat catatctttt atctcacaat
    84841 aaatttgtct tgataatgat atattactat ttctattaat cgtaatccac attctaatac
    84901 ctccaaaagt agttctataa aattactata aaaatggaac tataaaatcc acttttaatt
    84961 tgctaagatt atatcataaa atataaaata aaaaggagtc tatattatgt tagaggtatc
    85021 acataaagtt aaagaaattt atcccaatat taaatttgga gttatggtta taaatattac
    85081 acattcaaaa cctaataaag aaaatttttt agttcttaaa aactctacaa ttaaaaatat
    85141 tatagaacaa cacccagaat acaatcgcaa agaaaaaatt aaaacagagc ctgtttcaag
    85201 ttatataaag tattataaaa aattcaagaa aacttaccct gtattgcttc aattagaatc
    85261 tattctatta aaatcaaaag gtatcccaga tgtaggtgta acaattgagt caatgttttt
    85321 agcagaattg aaaaatcttc ttctaacagc aggtcatgac cttgataaaa tggaattacc
    85381 tttgaaaata gaattagcaa atggaagtga acatttttat ggtataggtg gtaaagaaca
    85441 tattttaaca aaagatgatt tatttttatc agataatatt ggtatattat ctagtattct
    85501 taatggccct gataatcgaa cagctataac aaaagatact aaaaatatta tgtattttgt
    85561 atatggacct gataaaatat cagaaaagca aattcaagac catttaaatg acataaaaca
    85621 ctatatttca agtgcttttc cagatttaaa agttaattca attgatatat tttagttaat
    85681 atattaaaat cctcataaat attttgaata aataaattag tgaagtatac attctagtta
    85741 aactagatat acttcactaa aattaattat atgtagatat tatttatttt gaattttgtt
    85801 tataataaac actttattac atttatccta atgaataact taattttata attaaagagt
    85861 ttcataagaa acaatttcac ttaaaggaac acgagttttt tcatgtctct ctgggctctc
    85921 tggtatctta gattcatatc ccatcaataa tatatttatt ggttctagat tatctggcaa
    85981 actaaactct tctctaatta tatctggatt aaaatagcac acccaaacac ttgccaatcc
    86041 aagttcagtt gcttgtaaca tcatatggtc tgtaactata cttgtgtcaa tatctgtaag
    86101 ttgtttccca tcaaaaggtc ttgtccaaac tttgtcttta tctccacata caagaattgc
    86161 taatggcgca tcatatatat tggcagcctt agaaagttta tttatacctt ctttttcctg
    86221 aataacaatc aatctttgag gttgacgatt accaccagtt ggagctattc ttgcaacatc
    86281 taaaaccttc tcaagttttt ctttttcaac ctttctatct tgataattac ggcaagaata
    86341 tctttttttt gcaagttcaa cgaaattcat ttatttacct cctattgttt tattaggcta
    86401 agttgatgat ttatttaacc tatgctataa ttttatcact atggtactat attacaataa
    86461 tgcacttttt tgtaatatag tacctaaaaa gatactttaa aataaataaa ggagcccaaa
    86521 aatgaaaaaa tgtttagata attacagttg cccaatagaa gcaacacttg cattgattgg
    86581 tggtaaatat aagacactta tactttggca tcttaaagac actatattga ggttcaatga
    86641 attaaaaaaa ttaattccta aagcaacgcc taagatgtta actcaacaat tacgtgaatt
    86701 agaatcagat ggtttaatta taagagtggt ttatcctgtt gttcctccaa aagtagaata
    86761 ctcgctatct gattttggaa agagtattat tccaatttta gattccatgt gtgactgggg
    86821 ttctgattac ttagaaaatc tataaaccat tacagtttaa atcccattgc taatttaact
    86881 tcatccattt gttctttaga tgtcaacatt tctaaaagct taaaagctac atgtggagct
    86941 gtttctggac aatatgaggt tataatattt ttatctacaa caattggttc attaactaca
    87001 tttacatcaa actcacttaa ctgtctttgt cttttaccat ttttcaaatg atatgtagta
    87061 gctttacgat tttttaaaac acaacttttt ccaactggca atgctgccac acaaatagaa
    87121 gcgattattt tttcttttga attaaactcc cttattagat ttaaaaaaga tgaatcatat
    87181 gcttcatcat aaaatccaaa ttcttcaaat cctccaggaa tagctagagc atcataatca
    87241 tcaacacata cttcttctat cgtcttatca actaatactt gtatattaaa tgtactcata
    87301 acttgttttt taaatccaca agtcactaca tcaatatcat gcccataatc gttacgagcc
    87361 catcccataa catctacaaa tacactaaat tccatagttt caaaaccttt tgctaaaaaa
    87421 actaaaactt tcatattcta ttttcctcct aaaatataat taacacttta ctagtaaatt
    87481 atttaaaaaa tatcttttat tgtattaaat tcttctttaa ttgtagataa aacaatggtt
    87541 gtattagctt tttgaatccc cccaatttcc ttcaaagtca ctgatataaa ctcttcaaga
    87601 ctacttgtat cttctgctaa tacttttatt aagtaatcat actctcctga aatatgatga
    87661 cattctaata cagtatcata ttccaatata gttttcttaa attctttcat acttttagat
    87721 aaatcagtat tgataaatat aaaagccaaa agcttatatt ttgttttttc ccgattaatt
    87781 tgaatagtgt acttttgaat taaatttgac tgctcaattt tccttatacg ctctgagact
    87841 gctggtactg ataaattaat ttgtctgctt atttcagagg ttgaagccct actattcttt
    87901 tttagagaat taattatttt taaatctatt tcatccagag ctactcacct ccttaattat
    87961 ttaatacaat tttagctaat aatttacatt aagtaaataa atttaatcat ttcaataaaa
    88021 tttaatacaa atatattatt tttccttaaa attttagttt tctttaatca aaacacatat
    88081 aatacttaaa attatttaag ttgaattaat gtttttattt tgtataatat attagaacct
    88141 taatatatca ttgaaaattc aacaatacta gacatatact tctacatgtt gtaatattta
    88201 tgaaaatagt atccctatat caaaattata aaactcataa tcttaatttt cttatagact
    88261 ataaaatttt attgatagcg agtcttcaaa taactttgta atgatagatt tactaaatta
    88321 atataataat agtaaatata actttcttat tgactataac taagtattat gataacataa
    88381 cttaagctat aattaataaa acatatttta aataaataag ataatccaca aagtacaaaa
    88441 gtacaattta aatatagata aactagaatt aatactaaga ttaggatgtg aataattatg
    88501 atttatatag aattagttaa acttgttaga aaacttaact ctacacaaat gtatacgatg
    88561 aagcgttgtg tagaggttaa tctgaaagct taaagctttc tatcttcatc ggcaaatata
    88621 ggtttagtat agttttttgg ctatgcttat ttaaaattac ctatttgccg atagataata
    88681 tagattttct ggtcatagac aacaatgctt gtctatgacc ttttgttttt ccaaaagcag
    88741 aggtcggcat tttacaatgc cattcctctg ctttttttat ttccataaat tttttaataa
    88801 aagaaaagga gtttgaatta tgagtttatt aaaagtaact aatttatcac aatgttttat
    88861 ggataaatca ctgtatgaga aagctaactt tgatttattc aaaggtgaac atataggtgt
    88921 agttggccaa aatggtacag gtaaaagtac attaattaaa attttattgg gagaagttgt
    88981 tccagattca ggagaaatca agtggcaacc taatatcaat ataggccatt tagaccaata
    89041 tgcagaaatc aatagagata caacaatatc actctattta cacactgcat ttgaagaact
    89101 ttataaaata gaaaaggaaa tgaatttact ctatcaaaaa agtgctatat ctgaaaatga
    89161 gcaatatcta atcaaagcat cagattatca ggaacaacta atagcaagta atttctattc
    89221 tatagataat gaaataaata aaatagcaaa tggtcttgga ttagattcaa taggaatgaa
    89281 tcgtgttgtt ggagagctta gtgggggtca aagggcaaag gtaattttag caaaattact
    89341 actttctaac catgatgttc tattattaga tgaaccaaca aactttttag ataaagaaca
    89401 tgttgaatgg ctctcaaatt atttaaatac atttaatggg gcatttatcg tagtttccca
    89461 cgattttgac tttttagaaa aaatttctac aggtattctt gatatagaat ttggcatgat
    89521 taagaaatat catggaaaat attcagagtt ccttaaacaa aaatcacatt taagagaaga
    89581 ttatattaga aggtatcaag cacaacaaaa gaaaatagaa aaagaagaaa catttatacg
    89641 taaaaataaa gctggagtaa attcaaaaat tgcaagagga agacaaaaac aattggataa
    89701 aatagaaaga atagctcctc ctagttttac aggaaaacca aatattcaat tttcagaaat
    89761 tgaaatatcg gctcaaaatg ctcttactat aacaaatctt gaagttggat actactattc
    89821 tttacttcca aaattaaatt tttctgttga tggaggtcaa aaaatagtta taactggttt
    89881 taatggaatc ggtaaatcta ccttgttaaa gacattagta aaagatattc ctcgtatatc
    89941 tggagatttc cagttttcag aacaagttaa aattggttat tatgagcaag atttaaaatg
    90001 ggaaaatcct gataaaaccc cacttcaaat agtagcagat aaatatccaa aattaaatac
    90061 aaaagagatt agacgtcatc tagccagatg tggtgtgaag gaagagcatg tttcaaggag
    90121 tgtatctact ttaagtggtg gtgaacaatc taaggttaaa ttatgttgta tgatgttatc
    90181 tccttgtaat tttcttattc tggatgaacc aaccaatcac tttgatgcag agacaaagga
    90241 tgctttacaa aatgctttga aacagtttag aggaagtata atcctagttt cccatgaaga
    90301 aaaattttat aaaggttgga ttgataaagt atttaatata gaaaaacaat tagtataagt
    90361 ttatacacaa tatacaatat tatttaattg gtatttcaat gcaaatttta atgttctagt
    90421 taatgtttca ctgcaaataa actaaaaaaa ttttattaga acataaagta cattaccagg
    90481 atataaactt aatgaggcta tctcaaaata gagatagacc tcttcttcat tgttgagata
    90541 acgaaaatac atttgatttc acccataaaa gaatgcctca ttaactaaaa attcaacttg
    90601 agatatcttc attaatatta aaatctattc taatcgattc tattcacaag tttatatcct
    90661 agtcctttaa ctgttataag tattttagga tttgaggggt tatcttcaat tttttctctt
    90721 atatgtcgta tatgcaccat aattgtattg tcacaaatac tactatatac tccccatact
    90781 tgttcataga gtctttcttt tcctataatt ttatttacat tttgagccat gtagcttaaa
    90841 agatgatact cccttccagt taactcaatc tcatttctat ctttatatac acggtttcct
    90901 tctatatcaa tagtaatatc tcctatttta ataacttcac tatctgatgg tacaatgctt
    90961 tgatactgtt gtctacgtaa ttgcgcttta actcgaaaag caatttctct tggactgaat
    91021 ggctttgtta tatagtcatc tcccccacta ctaagaccta gtattttgtc aatatcatca
    91081 ttttttgatg ataaaaaaag aatagaacag tatgaaaact ctcgaatttt tttacacact
    91141 tctataccat ctatatctgg taacattata tcaagaatga caacatctgg acatgctatc
    91201 ttacacagcg aaatagcatc tagaccatta taagctttaa taatgttttt aaaaccatca
    91261 tttatgagta cttcttcaat taaatctact atatcctttt catcatcaac aagtaatatt
    91321 tttttattaa aacatgtatc catattgaaa tctctccata aaaatttatt atattctaat
    91381 cttgcagtat cactatcttg ttttttatat tcactactct tgcttttaca ttactaatag
    91441 taacatctct aatagacaaa ttcaatcact atgaaaatta agataagttt ctttaaaata
    91501 aagtgtatga tacattaaaa cctatagaaa attaatttca tccaaagttt ataatattag
    91561 actaatacac ttacagatac agattaatac aatagtaaaa taaaaggagt tgtcttaaaa
    91621 ttgacttttt ctaatcaaac tttaagttca actccctttt aaacttttat atgttatttt
    91681 tattaattct ttatatcaat tataacttta attttcaata gtatatatct cccactaatt
    91741 gaattactta ttaaaacata aaatatctac ctaaactatt tatttaatat ctacatatat
    91801 ttatatctat tcttatactt acatatacaa aaaatggtta aaaataaagt taaaatctca
    91861 gcacttggta ctgctaacca tatcccattt atatttaata tatttggcaa tatcaataaa
    91921 cctatagtta taaatccaaa tgtacgtaga aaagataata ttgcagacac ctttccattt
    91981 gataatgctg taaacataga cgaagtaaaa atattatacc cacaaaaaat aaaactaaaa
    92041 gaaaatatat aaaatccaga ccttgcaatt tcataaactc ggcttcctct ttgagaaaaa
    92101 atctctacaa tgattggtga acatgatata gaaaagataa ataccaataa agatgctact
    92161 gaaataaata atatacaaat cttaaaaaca tgatttaact gcgtattatt ttcacttcca
    92221 tagttataac ttattattgg tgcaacaccc attgagaaac ctatataaag cgaagttaaa
    92281 agaaattgag aataaataat tattgtaata gctgcaaccc catcttcacc aattaatttc
    92341 atcatcatag cattaaataa aaaagtagta actgctgttg atagttgact gaccatttca
    92401 gatgaaccat taaaacaagc ttcaaataat attcttttat ctagtctggg tatacaaaac
    92461 ttaagtaacc ctttgttttt tgaaaagaaa accatacctg aaacggtagg aattaggtat
    92521 cctactccag ttgcaagtgc tgctccacta atacccattt gtaacagaac aatgaacaca
    92581 tagtcaagaa ttatattagc acacccagca cctaacacta gccataatcc aaattgaggc
    92641 tttccagctg ttacaaataa acattgaaat aatacttgta gtatatttgc agaagcaaaa
    92701 accaagataa taaaaagata tgaacgacaa tatttaatta aaacttcact tgctcctaac
    92761 catataatga tataatccat aaatacaata cctataccag taattattac accaattaca
    92821 actcctgata atacgattaa agaaaaagct ttatttgctc cctcaatatc accatttccc
    92881 atcttacgtg ctacaatagc acttcctcca gtggcaagca tagttccaat tccaactata
    92941 agattaataa ttggacatac aatattaatt gctgatagag catttgtatt aataaatctt
    93001 gatacaaata tagtatctac gattgtatac aaccccataa aaatcatcat aaaaatagta
    93061 ggaaatgcaa acttcaatag ggtaaataaa ttaaatcttt gtgccagtaa attatcttgc
    93121 tcataaagat tatcttgttc atgattttct gaataatata catcactcat tttgtttatt
    93181 tttctgtaca ttaattattt ttaaaatata ttccaaacaa ttagacattt acagacctcc
    93241 tttctgcata agaattatat ctaattattt ggatatagtt ttaattaatc ttgctttttt
    93301 acacaattat atttctacta aagaaacttt taaatcctta ctttaataat tttatagctt
    93361 tcagtgcctt tagcgcaaat acttgttcac atagtttagt gtcatatgaa acatatttat
    93421 atatagttat acattgtcta tttttactaa tttattaact acttgcactt ttataatgtc
    93481 tcatacctaa cttccaaaat ctccacataa acaatgtaaa caaaaataca attaaaattg
    93541 agtatattaa tccattaatt gttattgtcc cagccaaaat ttgagtcgga attgtcgaca
    93601 taattccata tggtaagatt aaatagaata atactttaaa aacaccttca tatattacac
    93661 caggaatttt catattcatt ggcaataaat tatcttctaa tctcattatc gcagaagatg
    93721 atataacaaa aaatgaaact gttctaagta tgatacatac atcataaaaa agtaatgtca
    93781 tcaataacac catgaaaata tatattatta tcatagctaa agttatctct gagtttaact
    93841 cagatattcc atataaaaca ataagtatac ttgctagaat taatggtgat gaaccaatat
    93901 taatattttc aaatgttaac ctaaatagtg gatctaatgg ttttgtaata tagtagtcta
    93961 attctccttc ctggattttt cgtggaatat cataaatacc aaaaaagaaa atcgtcatat
    94021 ttatcgcatt tattaatgag aaagttccta taaatattaa catctctcct tgtttccatc
    94081 cccctattga gtctacatga gaatatatac tattaaacat tagaagttgt aatataaata
    94141 atgaactatc tacaaaaaat gctccaaaaa aatcaaatct aaataccatc atctttgata
    94201 atttcatttt taataacata aatattattt tcaaattttt tttcatcata tacccacccc
    94261 atcaaataat gttctcattc ttttatacat aactttattt actacagaaa aaaataaaac
    94321 ccataatgct agaataatta atccttgtat tgcctcattg ctgtttctac ctattagtaa
    94381 catagatggc aaatatgttg tataataaaa tggaaatacc ttcataactg ttactatagt
    94441 ttctggtaag agtacaagtg gtatcattgt tcctgtaata aattcaacaa tattttcaat
    94501 tatcattcta aaaaaactaa tctcaagaaa tttaaatgac aaaatcccaa taaagaagtg
    94561 gagtttcatc ataaaaataa accctagaaa aatcatcaaa attgaaatta atatttgaac
    94621 tggatttgat gtaaaggcaa aatctatttt aaatataaaa atccatacaa atgcagaaat
    94681 catattaaat acaaaataaa aacatgtcat tccaaaattt ttagcaataa aataattttg
    94741 aacattaatt ggaataatca tgtactttga aaaggtgccc aattttacac gattacatat
    94801 ctcttcactg gtactctttg acatatcaat acctgctaaa aatgagctta ttatatagta
    94861 agataacata gagttaaatg taaaaccaga gactatttta ttttcaccaa aaattgcttt
    94921 ccataaaata taagcaaata aaatttttac aatcgtaaac accatattaa ccaccacatc
    94981 aaatctccag ataagttgca ctttaaaatt aattttggct acttcataat accttctaat
    95041 actctgttta aatttataaa acattgaata atttgaactt gcttcattat agttgctcat
    95101 aatactcatc acttcctttc ttatatattc tctctacaat actacctata tcttcttctt
    95161 caatcattac atctttaaca tcatatttat caaaaatcca tttaatcgtt tcatttcctc
    95221 tttcttttgg cacaattact gatgtcttat gatttgtttg ttcaacaact ttacaatctt
    95281 ttggaaatac aatgttagtt tcattggaaa aactaactgt tattttttta tatttttgaa
    95341 aatgattaaa taatttctct gtagaaccat catatatttt acgactattt tctacaacaa
    95401 tacttctact acagagactc ttaatatctt ccatgtaatg agaagtaagt ataatagtag
    95461 ttccttttgt ttcatttact tcttttagga aatacctaat ttgtttttgg gctatagcat
    95521 ctaagcctat agttggttca tccaaaaata atatttttgg attatgtaga agggctacta
    95581 ttagttccat tttcattctt tctcctaaag aaagcgtcct aacttgaaca tttaaatagt
    95641 cagatacctc aaataattcg ataaagtaat ccaagttttt tttatattct tcattagata
    95701 tatcatataa ttctttaaat aaaagaaacg tatctgctgg tgtcaattca aagaatagtt
    95761 gacttttttg gcccataaca acagcatatt gttttttaaa attattttct aatttgttag
    95821 ggtaataacc cattacagat atttctccag aagacggtgc aataatacca gttaacatct
    95881 taataagagt agttttgcca gctccatttt gacctattaa tccaacaaat tctccttctt
    95941 ctatctttaa atcaaatgac gatatagctg ttttttctgt atatttccta ttaaataaag
    96001 actttacact ccccataaat cctgcctttt tctcaaatct tctataagat ttagtcagtt
    96061 cattaagttc aattatactc attttaacta cctccatatt tcataattta tataaaaaaa
    96121 agtccacagg tatatatctg cctttttctg tgcttatatt taacagcaca aaaacagaaa
    96181 actcctgtgg actagaaaaa ttaatgctct ctatttcaaa ataattatca aaataatact
    96241 atacaaaatt aataaaagtg tagcagatta aagcctacta caccataatt taacaaagta
    96301 atatatattt taaatactat ttgttgtcat atgtcagtta tctataaagg cagaataaga
    96361 cacaaaaatt aaatgtatta aaaatacact tgaaatttct gattatacag aatatatgtg
    96421 tctccaacta tttaattgtt ggttaccatt atataactcc gacatcaagg cactcctctc
    96481 ataatattat tattgatatc atatcataaa ggttatttat gttcaagcat ggatttatat
    96541 actaatacat ttagcttatt tcttcaaggt tgaatttaaa tttcatttat aatattcgtt
    96601 tataaattaa aaatataata cgtatattaa aactggtcat tttactgtaa tatttttatt
    96661 gtaaaagata tacttttacc tatacaggat gtaatttctt tagttctata ttataataat
    96721 attgtaataa gagttcaact tataatacat taaaatataa actgtaaatc ttaagggggt
    96781 aatctatgga aaataataca atacaaaaac aattaagaga tttatcaaaa aaaatttggc
    96841 atatttatat tttaaatcca gaagaagaaa accttaaatt tattatttcc ttattagatg
    96901 acaaccttgc attaattgga acaggaaaac atgaatttta cgaaacatta gaagaattta
    96961 ttataggtct tgaaaaagac caaacagaat cagagcaaat agactttgag attatagatg
    97021 agtggtattc atgtaccaaa gtcacagacg aagcttttat agtatatggt actctttggg
    97081 taatagaaaa agattaccta gaaaaagata tctatgtaga aatggatact cgatttacta
    97141 tggtatacag agttacagat gatatgatta aacttatcca tgttcaccat tctattccaa
    97201 actttgacca aatgaaagat gagtattacc ctaaaacaat aactgaaaaa gcacaagaag
    97261 cactagcaat ggcaaatgaa tttaaactaa aatcagaaaa agaccttatg actggactat
    97321 acaatagaca tttttttgaa gtacacataa aagaaatgct taaaactgtt tcacatggat
    97381 acttttacat ctttgattta gataatttta aacaggtaaa tgatatcttt ggtcatgttc
    97441 gaggagatga aatactaata caattttcaa atattttgac taaagtattc gtaaatgatg
    97501 ctattattgg aagacttggt ggagatgaat ttgctgtttt tgaatatagt aatcaatcaa
    97561 aagagaatgt tgaaaataaa gcaaagaaag ttttagaatt atgcctagag agtaattctt
    97621 gttctatagg tatatctaaa ttagaaaata actctgatac tttccagtct ttatacaaac
    97681 aatcggatta tgctttgtat tattcaaaac gaaataataa aggaaacttt agttggtttt
    97741 agtgtaaaag atattaaaat aggcaaattt attagagtat cttgtcctat atactaatag
    97801 gtaaagtaaa caacaagcta tctttgcata tatttatata aaccaactat ttttaataaa
    97861 actacaatag tcaacatgac cactattata gaatataata aactaaaaac attattaaca
    97921 tgattaatat tacattttaa taattttatt tttaaaagta aatccaaaat gttatatttt
    97981 ttgattaaaa ctgatgttga tataaaaaat tttacttaaa aaaacattta gaaaggcttt
    98041 ataaagagcc ttttttgctt ttattgatta aattttcata taaaattcct tattaaattt
    98101 taaatcaata aaaaaggctc cataagaagc cttccctatt tttattgatt aaatcctaat
    98161 atagacaatg ccttagcatc atagtaagta gtcatctctc ttgttgcatc ctttaattta
    98221 cggtaatcaa agtctaatga tccaccaaaa gctgatattt cagacccatc aaacctatac
    98281 catttcccat caatttgtat atagttccaa gcatgattta atgatggatt taatatagat
    98341 agtgaatcca ttcccattaa ccttgttaat aaatgaaagc tacttgcaaa acttccacat
    98401 acaccacgtt tatcaaccag attaccatag actatgttac aatatttaga gtctgcatat
    98461 tttgcttcgg ttaccaattt tgcagctcta ttagctcttt ccatctcaga tgcatttctc
    98521 cagtcaaaac tatttaaaaa attcctgatt actgtaagtg tatcttgagc ttgtttgtaa
    98581 gaaatccaat ttccatcagc tattacttct atagggtcaa gttttccaaa gcctattctc
    98641 tgatatgaga cacctgacaa tgctgccgca taaaatccta gcccttccat acccttattt
    98701 atataataat atttaccatc tgctcgaagc tcaactccat tgggatttcc tccatagagt
    98761 aaatcccatc cctctttacc tgttgtatta agaccaagtt gtgttaacat tcctttaaga
    98821 ggatatttag ggtcataatt agcaccttta cttattgcat ttgtttgcac tctgccatcc
    98881 attgtgccta tattagtctg attacgttca tttgcactct gtttttccaa gctagatgtt
    98941 tcatcttctt gatatggctc tgccattact gtcatactca tcatcaatat aataatcatg
    99001 gtaatcatag tagttaatat attcttcttc atactactcc cccttattta attcttttta
    99061 aaacataaaa ttattaactc ataaatatat ggttattagt aaattgaaat taagtctgat
    99121 tcataaatta ttggtttaat agaagtgtat tgaaattgta cctttatatt ttcattatat
    99181 aataaactta tttttttaaa acatattgtt taaatcagta catttatatg ttttttttgt
    99241 tcatctgttt tatcaaatat attagtcttt gaattttgtt tgtattcttc agcatcttta
    99301 tctaactttt ctattctcga ctcaagtttc attatttctt cttgtgttaa atttataaaa
    99361 tttttaagca tattttcaag ctcttcacga gttttaccta ctaaagataa gtcctcagat
    99421 actttctctt ttttattaga atcctcttta taatcctttt tttgttctaa ctcttctaat
    99481 ttttcatcat ttaatatttc ttcttcaatt ttttcattag actctttagt gattaaagat
    99541 tctttttcat catttgtatt tagataagtt gaattttcat ctaacattgt acttttattt
    99601 ttatcttcta taatgctatt tttaatacct atttctatat tagaaaagtt attagttgtt
    99661 tctcttattt ctgatttaca taagttctta attgcgtcat ttattttttt agtataaacc
    99721 tcttgtctat attttaaatc tctaattcta tcattaagtt cttgcttttg tttcataata
    99781 ttagataaat aagtgtcttt tcctacagtt tcatttttct taaccatact ttcatttatt
    99841 cttgtattat ttatattact ttcatatcta aatgaatatt gacttctata ttgactagat
    99901 attttcattt atttcacctc tctaaaataa atttatgttt ataaaaacca acttagctta
    99961 attatatttt atcatcaaaa gtatacattt acaaatatta gttaatagtt ttataggttc
   100021 gagcattatt ttcaacaaaa aatttttatt ataaattaaa acaataattt ttataaatat
   100081 attatttgta ttttataatt catatatttt tactttataa attagcaata ttgcagtttt
   100141 gctcttaaga aacatctcta tcatacataa gcatatactc tattatgtat tagtataaat
   100201 atgccttttc ttatcttaca taagacctct ttataaagga gactatcgta acaaatatgt
   100261 atacattatc acatgtatat atcatcatat aaaaaatcaa actttattaa aaaaaataat
   100321 aaattgtttt aaataatacc acaaatcaaa tttgccatca aaatcacatt aaagtaataa
   100381 attaatggca aatttaatat attaatagta tatagactca tataatgaac aaaaaaacta
   100441 cacttatctt ctaatcttct tatttatttt tgagatattt ttaaatttct tttctttttt
   100501 tgctaagtat tcgcttttat tgtctgcaaa tactgcttca gttttaagcc tacgataaga
   100561 ctcccatctt ttaggcgaaa gttcttgatg agcaatagct ttccagatag cacagcctgg
   100621 ttctgaggtg tgagtacaat tacgaaaatg acattttccg aaataagctt ctatatctgc
   100681 aaaactttta tctaaacctt ccgaaacatc ccacattccc aactctctca tacctggtgt
   100741 gtcaataaca ataccaccac ctgaaattaa aaatagctct cgtctagtcg tggcatgtct
   100801 tcctttatca tcatctatgc gaatttcctt tgtatttaaa aattctccac ccaacaaaca
   100861 attaattaat gaagattttc caactcctga agaaccaagt aaggcaacag tacagcctgg
   100921 tttaatatac ttagaaatct gtttataacc atctggctct atagatgagg taacaactac
   100981 atctacaccc aaggctatgg aattaactac ttgtaattta cgatacacat tgtcacataa
   101041 gtctgattta gtaagtacta ctactgggat agctccactt tcccatgtta aagacagata
   101101 cctctccaat ctatgaatgt taaaatcctt attcagtgac atgcacaaaa aaacaatgtc
   101161 aatattagct gcaaccacct gttcctcatt tacctttcca gcagccttac gcacaaacaa
   101221 gctttttcta tgaagcacat gatgaataat agcattacca tttttattat tgcaacgatc
   101281 caacataacg aaatcaccaa ctgtaggaaa atcagattgt atagtagcct caaaacgcag
   101341 ctttcctgaa acctctgcaa acagtacacc atttacacat acagcttgat aaaagttctt
   101401 ttcctgcgag ataattcgag caaggtataa atcatgatat tccatacttt gagtaataaa
   101461 attcctattt agaccatagt cttgtaaatt gatttgtttc ataccattca ttctgtttcc
   101521 tccttttcca acttttcaat gattctttct agtgggaaag ggggctgtgc cagtggtttt
   101581 aatgcaattg acattaattt cactgaatta tcatcagctg caatacgatt agaactaaga
   101641 tgtccacagc gtgtacaacg atgaataatt gcccactcac cattttttct cacccacact
   101701 ccaataggtt ccatattagc atcacaatct gcagcacggt caccaggaat gatatctaca
   101761 tgaagactat gtaaacaatg tggacaatga tttctatgtt gtgtaccagc tccttcagga
   101821 actacaagac aaccacaatt tttgcaaata aagttatcca tacaggaatt ttcctgataa
   101881 taagctcgtt ttctattttt ataattcatt tttatttcct ccgtatcgtg tattttctac
   101941 aaaaaaagtc cacaggtatt tatatctgcc tttttatgtg gtatacatat ttacctacac
   102001 aaaaacagaa aacccctgtg gactagaaaa tttagtatct tctatttcaa cataattata
   102061 ttcaaaataa tactgtgtaa aattaataaa agtgtagcag attaaagccc actacaccac
   102121 aatttaacaa agtaatatgt aatattatta tttgttgtct aatgttagtt atctataaag
   102181 gcagagtaag acacaacaat caaatgtatc aaaaatacac ttaaaaattc tgattaaaca
   102241 gaacccatat gcgtctccaa ctatttattt gttggttacc attatatata actctgacat
   102301 caggcaagac actccttcac taataattat tattgaaatt ttatcataaa atataagtat
   102361 gttcaagtat aatttaatat attcatatat ttatgtttgt ctcattttct tattctataa
   102421 aatctagtgg tattttaaaa tttaatgttc acctagtatt aataataaaa attaactgct
   102481 attatttgtt ttctcatttt atgcctattg ctcaatttat ctcacttaaa ttaataacaa
   102541 ctgtcttttc atacaaaacc tacaatcaag tttttccata tattctacat gcatagtcta
   102601 tttttttgat ataaaataac gttcatattt gtaaatttat ttaattttca aataagtata
   102661 ttgaataata agcaattcta ttgtattatt gtaattgtag aataaaacta aatcggcaaa
   102721 actagagaaa tttagtgacg caaagctata gggactaacg cttataaaat aaactatgag
   102781 ttatgtcagc cagttgccaa aaagagatat tctttttgtt tttatgaaag ttttttaggg
   102841 ggataataat atatatgttt agagataaaa tggatagatg tacacatatg ttgactgctt
   102901 atattggtag ttcatatgat tattgtgatt ttatagatac acaactagat gattttatac
   102961 tagagtacgg agaaaatgtg gtagaatctt gtttgcatca agtgatggta ttagtaagta
   103021 agtataatta aatagatttg gttttctaga gaaccctttt tagttttatc tactttaaat
   103081 agccttatgt tagaaagcta attaagatag atttctagta ttcataattt tattttttat
   103141 ttaaaataca tataataaag atgtaaattt gtatcaaata ataaatatga gaacttaaat
   103201 tctcttatct atgtgaaaat aaacatctct taaaatgaaa ttctgcaaac ataaatgatt
   103261 ttttagtttg aaggattaga ttaacaaaat tataaatttg caaataagct atattaaaaa
   103321 atataataat tttttatata acttattctt ttataacttt taattttaaa agaggagaat
   103381 gtatataaga gtattcaatg tactagaaaa aatcaaaaga aatattagaa gaaatggata
   103441 ttgagtaatc aaagaaaaga ttttgatatt acaaatgata tgtttcaaga aagcattcct
   103501 atcacaacaa aaattattct tgaagacatg ccttcaaatg atgaattaaa tcatgttttt
   103561 tcaaaaggtt gtgaacgaaa aatgaaaaag agaaaaattg tattaatcac actactatta
   103621 ataggtgttt tgttattagg aagtatccta tataatcttt ttttaggaaa aacagctaat
   103681 atttcaatgc taaaggaatc ttggaatttt gatataccaa tacctaacaa agaaattgaa
   103741 gtatttgata ctcaagatag tattaatgga gatggacaaa attattttat tcaaggattt
   103801 tctgaaaaaa atttcaaaaa agtttttaat ttaaaaggtg gtatagttgt aagcaaagat
   103861 aatattaatg aaatagaaaa atatattgat aaatttaaaa gagattctgt taacattaat
   103921 aaaagtaata aaaataaaat tgaagaagat tttaaaaaat ataagttaga agttaaaaaa
   103981 gatgataagt atatatataa gagaaattat gagaactacg tagttttaat tataaaaaaa
   104041 gatgaacaaa aattatacag tttaatatgg aatcagtagg tacatatgta ttattaagaa
   104101 ttataaataa taaaaataaa ttttagtcaa tatacaaaaa ccttttaaat tgtctggaaa
   104161 tcacctcttc atttgttata aaaacataca acaaatgaag aggtgatttt atggttttaa
   104221 aaaaaataat tataagtgga tatgtgcttt cacatgttta tcaacatttg taatgcctat
   104281 atttgctaat gaattataat ataaaaatat taaataatat tcaactatag attatgtaaa
   104341 ttattctatg aaaaaaatga gttgtataaa atctggctac tgtagattga cgatttcttt
   104401 taaaattaca attataataa gttttataga attaaaaata aaactttaga gatttttgat
   104461 aacattgtag actaaatttg ccaccgaaat cgctttgcag tggcaaatcg gtggcaaata
   104521 caatatatta ttagtatata atctatataa acattactat tgcttgatta tcttagctac
   104581 agtttccaca tgtgtcgtta ctactatcgg aacacatttt atcaacctcg ttgctgtcat
   104641 gtgaacacaa ttcattagtc ctatgccgtc ctcttgcatt tttcctttgt ggtttaaatt
   104701 tagcaccatc tacgctattc ttcaagcctg ttttataaac aaaggtcaac tgtgcagggt
   104761 caacatttcc gttttcatca agtccaccta caattacttt ttcaacaatg ctttcaaaca
   104821 catagcggtc aaatttatca agaacctcat tctgttccag agttttctta aactctttca
   104881 aacgtttttt tatgtctttc tcattatcag aagtttcttg taacttttgt ctttcttcaa
   104941 caagctgttc ttgtttactt actaaatcag catatttact ttcgtaggtt tccttatcaa
   105001 taatttcttc cagacgcata tccacaagtt tacttttttt cttctctaat gcgtctatct
   105061 ccttttccgc ttttgcaagt tgttttgaca ccacactact actaagagta tcgtccattc
   105121 tctgcaaaaa ttcttccaga acatctttat tatcatcaca taataaacga taactttcta
   105181 caaatgcttc ttcaatagct gtttctggaa tacctttgct atgtttacaa aatttctttc
   105241 ctttcttcgt agccgttaca cattgccata taaccttact gtattgtgag ccactgtgcc
   105301 aattacgtct tgttaaagta ccaccacaaa agccacattc tagcatacag ctaaatgcgt
   105361 atttcctgct atacttctca cgcttaccgc tgcctaccgt tgttcggttc ttatttctcc
   105421 gattaagaat ttcctgtgct ttttcaaaaa cttcttcact aataatcggc tcatggtgat
   105481 ctttcatata aaatttatct tcttcaccca tgttttcaag gcgacgtttg gaaatcggat
   105541 caacagtaaa agttttgcct aagagtatat cacccttgta tttctcattc ttaataattc
   105601 caataaccgt agatggtgcc catgtggaac tcccatactt cgttttataa cctagacttt
   105661 caagctcctg tccaataaca gaaccaccag caccatcaac ataacggttg aaaatatatc
   105721 tgacaatctc tgcttcttct tgatttacag ttattgtctt atcctctggg tgataatcat
   105781 atccaataca accttgaaaa cctaccagct cgccgcgctt cattttcatt ttcaaccctt
   105841 tttttacatt ggctgaaatg ttctcgactt cctgctgtgc aacagaacta agaacaacaa
   105901 gcaataactc tccatccatt gtaagtgtat tgattttttc atcttcaaaa taaacggcga
   105961 tatttctctc ttttagcata cgaacatatt tcaatgtgtc taaagtattt ctggcaaatc
   106021 ttgatatgga ttttgtaaat accatgtcaa tttcaccatt catacagtca tttatcatac
   106081 gctgaaaatc ttctcgtttt gttacttgtg tccccgtaat tgcttcatca gcataaatgt
   106141 cagctaacac ccattccttg tttttcttaa tcatgtcagt ataatactga acttgtgatt
   106201 tataactgtt taactgatct tcgctatctg tacttacacg gcaatatgca gctacacgca
   106261 aacgctcaat ggcttttcca cgggcttgtc ttgacaaaac attttttgct tttattactt
   106321 caacttcctg catagtacac ctccttattt tgtgttcctt tcatattgtt attgtactac
   106381 tttaaaaaac acaattcaag cagttatgtc agaaagcacc ttatagtctt tcatcagcct
   106441 ttgttttaca agagtgtatt ctttttcaga aatcagttta cgggcaagca gttgttttaa
   106501 catagcaatt tgcatactat acctaattat attattcatt aaaaccctcc ttgctttttt
   106561 atttatggaa gtaatcagac ggcttcggca gctccactgg actttcacca ttcccattct
   106621 gatgggtgaa ccgtgtcata cgggtgtatc attattcaga tatacgagtc atggcagcaa
   106681 cctttccaaa gatcgcttgc ggttcactgg cataatcgct cgctgctttc cccctttcag
   106741 tggtcgtggc gttccagtcc gctggctcgt cgtatatcaa acgtatctga ttactgtatt
   106801 cacttgtcaa agaacggaaa agagttaaaa tgaggtggta gatactctct gttatattta
   106861 cttcactttg acttcaaacc ctaagattac tttaatcaac gctgcccgta tcctgccttt
   106921 cagttccata tcaagcacga tatacatatt cccgtgttcg tcatagaacg ggcgtaggct
   106981 ggcttttgat atgtaagcgt cataatggtt caaaatcttt tcaattgcca cctcgttacc
   107041 gtcagctgca gagctgatgg tcgagaatga tggacacttt tttgtagact tcatcatgtt
   107101 tttattcctc ctcgtacata tccttaataa gctttaatgt gtgcagcctg tttctacata
   107161 cggaaaatcg ttccatttcc ataacctctg caatttcagc gtcggtcatt tcaagaaagt
   107221 aggacataag cagaatgtta cgtcggcttt ctgttaattc tttgatagct tcacataagc
   107281 gttcatcata gatatggact tctgaaccaa atacatcaaa tgacgtaaac tcaacgcaat
   107341 actcgtccat gacaccgatc tggtttaact ccatttcaga taaatcacag aacggcgttt
   107401 cacgtcttgc acgtctgcca agctctcggt catagttctt tacagttcgt cctacaacct
   107461 tgcgagccag acaatcaaat tgaagtctga tagcgccctc gaaagaagat ggtttcataa
   107521 tctcaccccc tttccagcga aagttgctaa agcgaaaaga cttctacctc ttttcgcact
   107581 aacactcacc gtgaaaggtg ggatctgata cccaaccaca aaaatttttt gaaaaagttt
   107641 tatgcagtaa aaaagcacaa gggcaataca gacgtactga tcttgtgcta aacaaattat
   107701 tcctgttata tgctgtaaaa aaccacatat aggagcatta tgttctgtag aatttaaatg
   107761 tttttttaat gaactaccga tggtcgaaag ttgttgaata tgtaagtgtt tcatacggct
   107821 acccctagag ccgataaaac aagaccatcc agtaatttgt ccaacgttag gcaaaaataa
   107881 aacggcggct atataaccgt cgtcttattc aaaagttcaa aaagaactaa actaaaccct
   107941 ctaaagcagt atgtatttat aatcagtctt gcaaaataac aaagtagaat tgaaatatta
   108001 aggtagcaat ccttgtgcat ctaataaact tataggggtt acagcagacc acggaataat
   108061 attttgtata ctttcagatc aatatagtcc aacaaaacca attcccgata tttagtaact
   108121 aaaaagtaaa ctagagtaga aaacatttct ttgcaaaaca caaataataa gtaatggact
   108181 cattgacaat agattgagaa atccagtttt ttagacttag atagattatc tcacttgtaa
   108241 atgatttaag ttctttgact tcatatatag cggtataatc tgtcaacgtg atcattacaa
   108301 accataatgc ctatataaca tactttccaa gcaaaaactt tattctatta gttggggaat
   108361 acaaaatatt tatcattgtg cgttcaacat attctttttg tataaaaatg taattacaaa
   108421 acaccactca atataagata gataataatt tgaataggaa ttatcaatct acgtaaccat
   108481 tcattacctg taattgttgt tacaatagat ttgggattct gtttccatta cataattttt
   108541 ttatccttct ttcagagatc tcctcatttt atcgaagctt cttctacaga catacattcc
   108601 ataataaaat ctacctttga atattatttc acgatttcgt tatagacgcg taaacaaaca
   108661 ataaaaaacg aaatttcttt taagtaccat aatttttata tcgaaattac aattatccac
   108721 ttatatacag catttatagg taattcaatg ataaaaaaca catactttac tactaaattg
   108781 ccacaattga atgcgccttg atatgatagg gagattccac aataaaaaac tgtgcatctc
   108841 ccctgattca ttcatactga tatcttattt ataagactct tttgtgtctt tttttggttt
   108901 catggaccaa aacactacat tcattacaat aacaatcagc aacacaactg ccatagccac
   108961 ccaaaagccg atattaagac caagccattc ggtagttcca aaaagggtca tccaaagttc
   109021 tttccagttc atcattccac ctccttaaag cagttctccg aaatgacgga cataggcttt
   109081 ttttaaactt gttgccaaag tcatatacag cagaatacat ggaatcagat aagcaaagta
   109141 tgctgcaggc aatgcaacaa atccaagcat agttccaaac acagtaaacg gaataatggt
   109201 cagaactata attccagtca ttgttagcaa agtcaccgga gctgatgcac gactctgaac
   109261 aaaaggcagc tttggagtac gaatcatgtg aatgactaat gtctggctcc acatagattc
   109321 cacgaaccac cctgcttgga acatcccgat atactgtgcc tgaagcattg ccagttctgc
   109381 accgctgaaa tgagcaggca aatcattaaa taatacacca ttcgatacga acaatggaca
   109441 aaatacaaag tacataaaaa tataggttgt aaaatcaaag atagaactgg ttggtccaat
   109501 ccagatcata aaacttccaa cactagaagc gtcccattta cgaggtttgg taataaactc
   109561 ctcatccaca ttatcccaag gaattgcagt acaggataaa tcataaatta agtttagaaa
   109621 tataagatga acactcatca ttggtaagaa aggtaacaaa gcagatgcag caagcactga
   109681 gaacatattg ccgaagttgg atgaagcagt cattttaatg tacttgatca tgttggcata
   109741 tgtctttcgt ccctcaataa taccctgttc caaaaccatc agatcttttt ccaatagaat
   109801 aatgtcagca gattcttttg ccacgtccac ggcggtatcc accgaaatac caatatcggc
   109861 ggctttcata gctgcagcat cattaatacc gtcacccatg aaaccgaccg tatgaccatt
   109921 ttcacggaga acagaaacca cacgggcttt ctgatcaggg gttagctttg caaatacatc
   109981 tgtagactct gccactcttg caagctctgc atcgcccatt tgttccaaat cagaaccgag
   110041 aagcatattg cgaacctcta atcccacctg cttgcagata gttcgagtca ctttgtcgtt
   110101 gtcacctgtc aaaattttgg ttataacacc atggtctttc agagctttaa tagcatccgc
   110161 agtagattct tttggaggat caaggaatgc cagatatcca atcagtacca tatcacactc
   110221 atctttaaca ccaaatgcgc cgattgggga aggattactc ttctgtgcaa tagctagtac
   110281 gcggaatccc ttatcgttaa gattgtccac tgtctccaga attctgtaac gaacgtcatc
   110341 agtcagaggc tgcactcctc cattacactc tgcaaacgca caaatagaga gcatttcttc
   110401 cacagcacct tttgttacca tctgggtctt acccttatta tcctgtacca ctgtagtcag
   110461 acgacgacgt gtgaagtcaa aaggaatctc atctactttc acatagtttt cagacaggtc
   110521 aatgagacgc gaatctgcgg cttcctcttc ctcagtctta tggataattg ccaaatccat
   110581 caggttttta tagccagtct ggaagtaact attgaggtaa gcgtgacgca gtactcgcgt
   110641 atcgtcctcg ccatttacat tcagatggta ttccagcaca accttatcct gggtcagcgt
   110701 gccagtcttg tcagtacaga gaatatcaat agcaccgaag ttctgaatgg aattgaggtt
   110761 tttaacaatt gtctgcttct tgctcatgga aacagcgcct ttcgcaagac aggttgttac
   110821 aatcatcggc aacatttctg gtgtcaaacc aacagcaata gaaacgccga ataagaaggc
   110881 cgccaaccaa tcgcccttgg tgataccatt gacaaagaat accagcggaa ccataatgag
   110941 cataaaacga atcaataccc aagaaacggc attgacaccc ttggtaaagc ttgtttcaac
   111001 cgcttctcca gcaactgcgg acgccataga gccaaacaga gtatgatcgc caacacaaac
   111061 aacaacagct gttgcgctac cagaaattac attactcccc ataaaagcaa tgtttgtgta
   111121 atcagtcacg ctttctttct gagcacttac attgggtgtt ttttcaatag gttcactctc
   111181 accagtaaga cttgcctgac tgacaaacaa atccttcgca tccaaaatac gaacatccgc
   111241 cggaatcata tctccagcag aaagatgcac aatatctccc accaccaaat catccatagg
   111301 aagttctttt ttttcatagt ttctacgagt aactgtacaa gtggtcgtaa tcatggctaa
   111361 caatttctct gctgcatttc cgcttctgga ttcctgtaca aaacgaagcg taccggaaat
   111421 gaataccatt gttaaaatga ttacaacagt cagggaatca aagtcctctg gcacactgcc
   111481 aaacagagaa aaatacggaa aaatcatatc tgtaattgtg gatactaaag ccagacaaaa
   111541 taaaatggcg gtaaatggat tgataaatgc gccaaccagt cgttttgcca gagatttctt
   111601 tttttcatga gtgactttat tggtaccata tttagcacga cttacggata cttcatctac
   111661 ttctaagcca cgaagtgtgg tatgaagttt ttttaaaact tctttaatag gattggttgc
   111721 cgcaaattga atgcggcggt tctgttcgtc acggatgact gctttttcta cagtctgacg
   111781 aatagccata cgattttctt ttttgttcat tggtcttacc tccttgaatt ttcatagggg
   111841 caaggaatat tatatgagcg acacggaatc tccaaattct catataatat tctctgcctt
   111901 cgtggactga catcagagtc catgtctttc acctcacaat cttaaaaaaa tatctatgtg
   111961 aaacctcaat gtggattatt ggttgcgata gcggacactt ttttcgatat accagacatc
   112021 aaagccggca acaatcagcc atgcgattat tgcaaataca aaccagtggt ttgaaaatcc
   112081 cggcaaaaat cctttcatta agaatataat cccatttaac gcaatcattt ctccaacatt
   112141 acgacaaagc gggacaatat taattttatc tttctcctcc tgcggcatat ttttccacag
   112201 ggaaagatga cgatatcctt ttccaaaggc caaccaaaag cctgcaagag taaataaaat
   112261 tccaaaaaag atacatgtaa aatccatcgt ttgttcctcc tttcaatgct taaacctgtt
   112321 tcttagtttt gtcagcttca gaagtttaat gaagagcaca ataatagtaa cagcaagaat
   112381 aaaccagatc acaatactca cctgatacca tatcttaaag attaccattc tttgttcaaa
   112441 gaaattccaa cccaaatagc tacataagat tgtaaataca gggtagaaag caaaaagaat
   112501 tgctcgtttc aaatcttcga tttctctcct cactcacaac acctcccaac cagcactaat
   112561 cacttccgga attaccaata cctgcccaac gattccttct aaaatattgt ttttggattt
   112621 tccgacagaa cagtattctg cgacaatctc aaccttgtca ccaaccacat caccgctttc
   112681 cagattgttc aaaaagagcg tcttacagga attgctgtta atcagcaata agcgtatatc
   112741 ctgctctgcc ttttcctgac atgtaaccga aatacgatac tgcttttcag attcatcact
   112801 ggaagtaatt gggtgaaact ttcttgcaaa gggacgtaga atcaggttgg aaccaattaa
   112861 aatagtagcg gcggtgatcg ccattgcata cattcccgta cttgcaagaa ttccaatcgc
   112921 tgcagtacac cataaggtgg cagcggtatt cattccacgt actgtccctc tgtccttgaa
   112981 aataacacca ctgcataaaa aaccaacacc ggatataata ctgcttccga cacggaatac
   113041 ctgatccgaa ccgtagagca taggaaacaa ggtaaagaaa cttgtaccca tgcagattaa
   113101 cacattgata cgaatacctg caggatgacc agtcaattgc cgttctaatc caataagaaa
   113161 tccaagtgtt aaggagaggg caattctcaa aataaaatct gtgtaaaaca tatgaaacac
   113221 ctccctttaa ctactaacag tatataaaaa atccaaatac aatcctatgg ctaaagtctt
   113281 gcgattttct tgcgatttgg taagaaaata gacggactga aaccgaaaat ggtcttagtc
   113341 cgtctttgtc atatctgatc attaaatttg tatccaatac cccagatggt caaaatatat
   113401 gtgggacaat ccggagcagg ttcaatcttt tttcgcaact tccggataaa agccataatg
   113461 ttgctgttat ccagaatata atcttcctcc catacggcac gataaatctg ttcctttgta
   113521 aaaacttcac ctttgttctg gacaagaaag tacaaaatat caaattcctt tggagtcagg
   113581 ttgacttcag aaccttttat cagtactttt ctgcctcttg gataaatttc cagatcccct
   113641 gccaggattc tatctgacag agtacccact ggccaatcgc tttcttctga tgctcctaac
   113701 aataacgaag atacctctcc acgaatcatc tcctgaatac cagaaagtaa atccttcgca
   113761 caatcactgt ccggtggatc tcttagtagt ttttctaata gccagatttc aagagccgaa
   113821 tccatcggaa tataactaat attctttttc atcatgaatg cctcctctta aatcaactct
   113881 tgatattttt tcttataaaa atatttggct actgaattca gcagcatata gagagatacc
   113941 accagcagta aaaatacgaa ataccaaaga ggtaatttcg tcagtccaaa caacgacgca
   114001 ccgccgacaa atgtaaggga agtaaaagca ataatcccca ctagagttat agaaatgacc
   114061 ggtgcagatg ccctgctctg gaaaaaagga atcttggaag ttcgcagaaa atgtaaaatc
   114121 aaaacctgtg tccacataga ttccaaaaac catcccgtct gaaacagtgc tacatactga
   114181 agttgcaggg aaggatctgt aagctgcaga taggttgccc ctccacatag catcggacat
   114241 aggaaataat acaaaaatag gaaggtgaca atatcaaaca gagaactgat cggtccgaaa
   114301 gacagcataa actgtctcag tgttttgccg gaccagtctc ttggggacag catctcttcc
   114361 tcatctacat tgtcccaagg aagcacaata cacaacgtat catacagcag attcaaaagc
   114421 agaatctgaa ttgaagtcat aggcaggaac ggtaaaaagg cactggcaca aatgatggaa
   114481 aaaatatttc caaagttaga gctagcggtg attttaatat atttcagcat attggtaaaa
   114541 gtttttcgcc cctccattac accttgctcc aaaacattca agtccttttg cagcaaaacc
   114601 acatcggcag catcttttgc tgcgtccact gccgtatcta cagagattcc cacatttgct
   114661 tcattcagtg ccggaatgtc gttgactcca tcaccaagaa atcccacgga atgaccatta
   114721 tcctgcatag cagagacaag acgcacctta tgtcccggag taagctctgc aaaaacatga
   114781 gtatgttcca cagccttttt aagttcacag tctgtcattt catccagttg agtaccagtt
   114841 aagatacgct ctgtagaaat acccacccgg cggcaaacag acacagcaat cgctgcctgg
   114901 tcccctgtca gaatcttagg gatcactttt aatcttttga gtgcagttac agactccttt
   114961 gctgtctgct ttggtgcatc aaagaaggat agatagccaa ctagagtcat gccccattcg
   115021 tcatcaggag ttattttctt ttgcgctccc acattttttc gtgccaccgc aatgaccttc
   115081 attccgtcct gtaacatttc acctactaca gaagatacac tatgtctcgc atcctgcccc
   115141 atggggagaa gttttccacg atattctaca tggttgcagc gtgagaatat atgttcaata
   115201 tcacctttca taataagctg actattccca ttgctatcct gtacaagtgt actgacaaac
   115261 ttacgagcat agtcaaaggg aatttcatca gctttttgga attttgtcag aagatttgcg
   115321 taatgggctt cccgccctgg catggtattg caggcaagaa tagcattatc aatggtattg
   115381 cagacaccag aatgatagca gctattcaga taagcaagat caagaacctc tgcattttca
   115441 tttccaaaaa tatccatata atattccagc aggatgcttt cattggtaag tgttcctgtt
   115501 ttatccatac aaagcacatc catgctacca aagctctgca tggcattaat atccttgata
   115561 atggtctgct ttttgctcat agcaagactt cctttggcaa ggcaggctgt aataaccata
   115621 ggaagcattt ccggcatcag acctacagca actgacaggg cgaaagcaaa ggattccatc
   115681 cattttccat cagtaatccc cagtaatata aatacaatgg gaactaatat cgccataaaa
   115741 cgtatcatca cccaggcgat ggaatcggct ccttttttaa aggaattttt atcatcagaa
   115801 tccggtttgg taaatcctcc atacagggta tctttgccta ctgccagtac aatgccttcc
   115861 ccttttccac tgatgactgt ggttgccata aaagcgaggt tttcaagctg agtcagtgta
   115921 tcctgctctc cgtaactgag ttttcggcag ctcttttcaa tgatggcgct ctcaccagta
   115981 atcgcagcct gagagataaa gagatccgta atcttcgtca atctgatatc cgccggaaca
   116041 cgatcacctg cagagaatag tacaatatcc cctaccacta attcttcgcc aggaatctct
   116101 attaactttc catcacgcct cactgtgacg ctttcatgaa ctaggcgatc aagctgagca
   116161 gcagcgctct ttgctcgcag ctcctgaatc agacgaatta cgccactaat tacgatcatg
   116221 gaaaagatga taatggcggt agtagcattt ctcgcaaaat tggatgctac gaaaacatcc
   116281 gtaacaagag aaacaatgcc cagaacaaaa agaatcacat gaaacgggtt aataaatgcc
   116341 cgtctcaacc gttgcatcgt cgtatcattt ttccgcccat tgaagctgtt cgctccgtat
   116401 ttctcccgca ttgaaccgat ttgctcaatg gataaaccat ccggagatga gccaatgtct
   116461 cgataaattt ctgatgttct acagtatgcg tattttttga tacgactatc aaatagtgtt
   116521 gcttttgaca cgaaacatcc cctcctttat aagtataagt aataacattt taacacagtg
   116581 ctctgaaaat tctatattta tattcttgct tttttcttgc aatttacttt gatatggcat
   116641 ttttcagctc gatcaaatcc gtctcgttag ggtgagataa atccttatca aagttttcaa
   116701 ccattccttc taaatttgga gcacggatgg atacggcaag cattttctca tagcgctctc
   116761 gcacataaat aggcatttcc ccttgacaca tatgagtgct gacaaacttc ttcttggttt
   116821 tcaccttgac catgtatcaa atttccaaat aactacttag aaaagttgct cataataata
   116881 tttgtattat gagtgataga atgacaaaag tggcagtatg gaaaacgagt gtaaaaacaa
   116941 tacaattagt ttgtatggaa tatctgaact acataattga ccactctgta atttatgaaa
   117001 aaatacaatg cgcaaattgg aacgggacag aagaaaccaa tagtattttt aataattccc
   117061 cttcaccatt gattactctt atctattctt gcgatttaca acaaaataaa acaacataaa
   117121 ttttaaatac gttgactggc ataattcata tgtatagtaa gtctacaatt aagatgcgct
   117181 ttttctaatc caaatatatt aagaaaaaaa ttttgcgaag ccattaatac tttgtttaag
   117241 atgtctttca taaatataaa gaataatgct cttaacaaaa gcgtgcaaat tcctaaagaa
   117301 atgcacgctt tcaataatta tcctataatc ttccagttgc tatccttatg tagcactaat
   117361 tcaaactgcg atacctgtgt tgcctttgtc tgattatcaa tgaatttcac ggcaaccttg
   117421 actttcacat tgtccccatc aaccgtaaag atagggttta ccaattcaga atagaggtag
   117481 tccctgccga tagactcaag cacatttcca gacacatagt aagcaagctc cttttctgtg
   117541 gctgttgggt atagcttaaa gaaagtttcc agaaatgcag tagcgtcatt tatggtatca
   117601 gcgtctacac ttgcgtctgc ttctggtgtc tttggttcat agtctgattt ctcgattgct
   117661 ggtgcaaggg tagggttctg aataattacc atattcccgt catcgtccac atgaactttt
   117721 acggtatagg ttgccttaac cgctgttgtc tgttccccct cttctatctg ctgatctact
   117781 tcgtaggtag cagaaaaagt gtccgttcca gactgttcaa tgctccatac aatcacatct
   117841 gtaattgtgg agctggtcgg aatatcggtt ctaatggtat ccacattcaa gtcctgcaat
   117901 tcctttgtca gataaccgtt gattgcctgc gtccttgctt cgatagcttc tttgctgtta
   117961 ctccatgtat aataagactt tgcaaagttc ttcacgaaat tttctatccc gttggtgtcc
   118021 tgcaagcgaa gctctatcac ttctttttca tgggtcgtat gctggtcgat agccgtaaaa
   118081 ttcttataca ccccaaagct cacgctttcg ataagcacta cccacaacgc aatcacggtt
   118141 ttcttatgtg tgcctacctt gacagtacgc accttttttt ctttgacatt ttctgtcgat
   118201 ttcttattct tcttaaacat attttcaagt cctttctatt cttttactcg tcctgcaccg
   118261 attaagtgct gttgccagta actactactt aggtctgcat atcctatcgg gtcgcctgca
   118321 tggtacattt tgttatttcc tacataaatg ccgacgtgtg ttacataact tccagcgtta
   118381 taggtggaat ggaaaaacac caagtcccca gcctttgcct gcgaaagagg aagatgttgg
   118441 gttgcgtcat actgggcttg tgccgttctc ggtaaggaga taccagcttt tccatagcac
   118501 cattgcacaa gtccgctaca atcaaaggaa gtgttcgggt tactaccacc atacacatac
   118561 ttccagcctt gatatttcaa cgcttcattc ataatcgctt gtgccgtcgc attatcaaag
   118621 tgtgccacgg tcagatattg attgactaat tccacataga acatatttcc atagccatac
   118681 cgccagcccc cgttcttcgc aacagctatc gggttggtgt aggttacttt ctttccaacc
   118741 gatttctcac gtgcgaagct ctctgcaagg ttaaaggtgt gtttctttcc tttgcctgcc
   118801 acatatccta catagccacc gccatagtta taggattgta tcgctacatt caaatcgtcg
   118861 ataccttgat ttttgcagga agaaagcagg gacgcaaaat acttacaccc ctgcttgatt
   118921 gagctttccg tatctaaaga gttgggcagt agtcccagac tttccgaact ctgcataaca
   118981 tcttctgccg taccgccact ttctacttga atgatagcca gcaacacatg gacgtactcg
   119041 gaaatgccat tttctctggc gtacttttct accataggct gatgtttcaa gacttctgcg
   119101 gataagttca tacccgtaat gccagaagaa aaattgctgt tctcgtcgtc gctgtccgca
   119161 ctaatcaaga cacccaaaaa aagcaccaga gaaaagagga taggaaacag actgccaatg
   119221 atagcgatat gtttcagttt cagtttcatt ttttcttctg tcctttcttc gttacaatgt
   119281 tacggttttt ctctgtggtc tgctggttct tttggacggt ttgggtctgc tgaacctttg
   119341 tcctgcggtc tttggtgtaa ttctggcgtg tttcctgcga taccactttt tctacattct
   119401 gcctatgtac tggctgtgcc gactgggtcg ctttcatatc agaagcacca gaagataacg
   119461 gacgctcttt gataacattt gtcttgactg gctcacttgc tttagaagtc ggagctgtgg
   119521 cagggcgttt gatttcctgc attttttcaa cactcgtctt tggaacggtt gaagctgtgg
   119581 ctggtcgctc atggggacgg gtagctcccg ttgtcgctga tccgtccgtt tttctatgcc
   119641 ttgcttcttg tgccttttga agctccatac gcttgacagc gatacttttc ttatgctgtt
   119701 cctgcttttc caagcgtccc gtctgtctgg actgctgttc ctgcaccata ccacgcttga
   119761 aatcagacac gctggacttt gccttttcct ttgcggaata caccgcataa gcggtctgtg
   119821 tgggcatatc cttgatattc tctttgacag cgtttgcctt gtctttcact ttatttttcg
   119881 tatctaagac agcacccacc tttgagcctg cacgctgtcc catactggaa gtggtattgc
   119941 cccgattttc tttagaagcc gtattttttc tttcggatct cttgccagca acggcacttc
   120001 cagctaccgc accagccaca ccgcccgaaa taccgccagc acttacagcc cttgcaatac
   120061 ggtgttccat acgcctagcc cgatgtcgca tgaacagata cggtctgcgg aatatcctgc
   120121 gtcccatgct ttgactgtcg ccagcgttga gagaaaacat actcattaag tcgcccagct
   120181 tcatatagat accagcgaaa catactatct gcaagaacgc caccatgaaa aacggatagt
   120241 ccgtggatat gttataaaac atactggaaa tgctaaacgc aaccgttata atgagcgtta
   120301 ttcctgcccg tgtcattatg gtattaaata ccctcacgat tgcctgcttt gccatgcttt
   120361 catagctcgg tatcatggaa agtagaaagc tgataggtaa aaacatagcg aagataataa
   120421 aaagtatctg gctgaacaac atcatacccg taagcaagaa tacaaatatc gtaataccaa
   120481 gattaaagaa caagaggaag aacaccatac ctaaacggtt taccacctgc ggtatcgtca
   120541 gattgttgtt gtcgttgtcc tcgatttctg ttttcacgac ttcttctctg gtctttccgt
   120601 cctcgtcctc tggacttgcc gatacgagag cttcgacacg gtctgtcccg atttcctctg
   120661 cgttgctgtt tccaaactgt aagagtagcc acggctgttg tacttgaata gaaaataggc
   120721 tgtcccgtat caagtctacg ctgtccttgc cctcgctgtc agagttgggg agcatgattt
   120781 ttgttcccaa atcaagcgaa gcggtactga tgtctgatga aaattcattt atcttcttga
   120841 tgtagtcggg agcgtaggca ataaacgaag cggacaacac gaacaccacc acaaagttga
   120901 taacagcgtg aagtgccttg ctggtttccc gttttatcag tcccgtatag gcaacataca
   120961 ttcccaccac taagataata agaagcagga aaccaacata gaagcccgta gaagaaaagc
   121021 cgttctcggt aacgcctgca agggtctgta tgctttttcc gatactgtct gccatatcgt
   121081 taataaaatc aagtttatag gcttcctgca ccacatagcc agttgcattg cttaaataaa
   121141 ggcttatcgt ccagacaaag ttggtaatgc agtaaagccc gtactgtacc gattttccga
   121201 taccgtccag ccagttccac ggaagccacg accagctatt atcgacgaaa aaatcaagct
   121261 ggtagttgga aagcggatat tttgaatata gattttctgc gtttatggta tcgtccacaa
   121321 gccccgtcgc atgagccacc gtccccagaa gtgaaagcag gataagggaa agtgccacca
   121381 cgaacagagc cattttgaga aagtgaagta tcttcctttt tgtgaacgca ctctgtatcc
   121441 tttctttcat cactccacct catttctctg tacgggcggt ctagtatcaa aggcgtgtag
   121501 taattcttca aagactgggt gtatctgcac cacaccgaca cgcccgtata agtcctgcaa
   121561 taaacattgt ccgttctcca aatcacgcaa gcgtttctgg ttgttttcgt cgtccttgtc
   121621 gataccgaaa aattctaagg tctgctttat ctcgttgatg tcagtagaac gaaatgcaaa
   121681 cttcaaaccg atattgtttt tcagactttc ctttgacacg tcataggcag actgggtaac
   121741 gaaataaacg cctgcctgca tagctcgtcc agcacgaacc agcttatttg atagggtttc
   121801 gccttgtgcc acatttaaga acgcccacgc ttcgtccaaa tctacaatct taaaaatgct
   121861 tctgtccgaa tggataaaat caagggcaaa ggtactaatc acaatcagca tagacaccga
   121921 caataattca atggtcgtgt attcctcaaa agtggtatct ttatctggca gtacaaggtc
   121981 tgctacttga atgatattga gctggttatc aaggcttata gcattttcta ccgtcccgtc
   122041 tgaaaacagc aggtgtgcaa agtcgtagtc cgtgaagctg tcgatatggt ctgcgatatt
   122101 gcgtgagata gcggtatctt cttttctcaa ttcctcaata acgtgtaaca gtcctctatt
   122161 ttcactctgg gtaacagaac gcaccgcttt tcgtaacacg gggaattttt cgccgtccct
   122221 agaggaaata cccgtaagga atgttaagat gtcgattgcc agactttcag cgtctttcac
   122281 attcttcata atcacaaatg ggtcaagaag tcctgcattg tccttgtcgc tggtaaggtt
   122341 tacgatattg atttcatggg ctatctctgg gagcgtttct ttccagttgc cacgctcact
   122401 tttagggtct aacagaagtg cttgaccgcc aaacagcacc gcataatata caagtagatt
   122461 gttgcagaat gactttccac cgccaagact tcccacaaaa gcagaagcaa gggcattagt
   122521 aactgtgcct tttactccct gcgaagctaa agacggttgc aggtacacat ttcttcccgt
   122581 atcaacggaa tagcccatat agatacccgt gttttcccct aactgctggg tcgcaccaaa
   122641 accaagccca gccaagaagt ctgactttac atactgcaca tagtcattga tatatcgctt
   122701 gctggcaggt aaaaattcag aatgaagtcc caacatatcg ccagcaggac gcaccagttt
   122761 tacattgagg tcgtcgtaaa agtccttgac ttcatcacaa cggcgtttca gctcgtcaag
   122821 atcgggtgca gacacccgta tgacgtagct taacttatac atactttctt tgctctggtc
   122881 taaatcggtt tccagctcgt ccacgctgtc taaagcgtcc accacatttg agctggtttc
   122941 acttcctgct tgataggcgt gattatccaa atctttcaat tcctttttct tgttgcggac
   123001 tgtcgttaat gccttacggt tctccacgat ttctacattc atagaagtat caacggggaa
   123061 tgtgaattgc tgttgctgga aatagaagat ttcagaggac ggaaaatcca actccccgac
   123121 aattacattg acggtaaaat aggacacata gctttccttg tcctcatgtt ccaatcgtaa
   123181 ataccgctgg ctttcctcaa tcacacacct tgtcggacgg ataaggtcgt agtattttat
   123241 cagcgtttct ttcttcaatt tcttctttgg tagctggtac tcataatctt cataggcgat
   123301 accgtccctg ccgtaaagat gttccatgag atacccaaaa tcatggattt ccaagcgacg
   123361 caccttaaag cgacgggaga ttttattttc cagtaacttt tccattttca tgtaacggtt
   123421 gatttcatca ttcggcatgg aaacaaaatc attcatcagc gtgtggttca cttcatgaag
   123481 aaattccttg aacgtcagcc atgccgattt tttgatgttc ttcagattga gctgttcttc
   123541 cgtaaccatg agcttaaagc caagaaaaaa gcggtagtcc acttgattgt ccccaatcat
   123601 tgatactaac gcttcggtct gttcgtctat tttttggact gccacctcac gaagtttgcc
   123661 tgttaccagt ttctttgact gctcctgcat acttctaatg gagctttctg tggcaatctg
   123721 caacgcatga atttttccct cacgggactg tgcgattagc tgtcgaaaac tgtcatgcac
   123781 gataaatttc tgctctgcgg atagaaaaga atagttgtac ggtatcagct catagtaggc
   123841 gaacacctca ttgtccttgt tccagacaag gttattgtca atatatttta tcgggaacat
   123901 agttcacact ccttactgcc gtgattgttt cattcaatat ctgcttatgc agttttacgg
   123961 cttttcctgc ataagtgatt ttaggtcgca aggcataggt tatctgtgat ttcaaaaagc
   124021 tgtacggctt ctttccgtca aaggttttct gcgacataaa ccaagtgaga gcaacgggaa
   124081 taccgaagta tttgagaaat gctccctcaa tcatggaaag tgggggcata tccccaaaca
   124141 gaatgatgat aaattccgta atcacaaacc atgtaatctg tgtaaaggta acgggaaagg
   124201 gtaagttaaa gtcattgatt gcatataaga ctttttccac gttccagata cccgtgtagc
   124261 ttttaatctt tttcaagttc tttcagcccc tttcgtaagt tcttcaaaga gaaaaggaca
   124321 gccattttca gactgtccct taaagagaaa tacgctgtca gtagcaacaa tgcttgttgc
   124381 tgatcttcca gcgttaatat ggtatctcac agatacctcg gcttgtttca atgaatcgac
   124441 cacccatatc caaatctcgc ccgtaggctt catagtcaat atagttctgt aagttagctg
   124501 gaatgtcccc aagtgcgttc aattcgtcta tgtagtagta ggcaacatct gtcatggttt
   124561 cacaatcggg ataaaaataa atatcgtcct tatgttccac gacttcttcc agcgtcccat
   124621 agtggctgat aaattcgtcc agacactcta cgatatagtc gggaagttcc tctatcattt
   124681 catacatttc attgagttct tcaatggaaa catattcccc tatgtcgata ggaaagttgt
   124741 cggtatcatg gacagcgtat tcttcgtact gttcattcaa gccgattttt tcttttacat
   124801 cttcctcgtc aatagggaaa gtgaaccacg caccgactaa atatccctca ttgtatctgc
   124861 caagattagc aatataaacc gccatatcat caatcataag caccacctca tttcctactc
   124921 tggcagttca aagataccgt gttccgttac taaaaatttt ccgtgttcct gcaagtgaga
   124981 agcataggct tcaaagtcaa aatagtattc ttgacagtcc tcggataaat gtttgaatgt
   125041 cgggtcgttc atcagctttt gccttgcaac atcaatcatg cttttgcagt cgggataaac
   125101 ggtaatcacg ttcctgcaaa tataaagtgc ttctaaattc tcatacacgg taagtagtga
   125161 tacatattct tcctgcatat cacttgaaag ctggcggtac ataaaatcta attcgttgag
   125221 ctgatacacg ctggtgtgtt cgtggacttc atcagcataa ggcagtacct tttcgataat
   125281 gcggtaatcc ccactttctg caccgacacc taatttttct tcaaactcgg caacatctat
   125341 cggcaggtca aaccagtatg atattgtttc ttcgccagtt gttcctctcg tttccaccag
   125401 cacccttgtt tcctgcattg ttcctcacgt cctttctgtt gtttcctcac atcttttatg
   125461 gtctggtacg acataccaaa cacatacttt gaaaaatctt ctaactgttt ttcttcataa
   125521 tcggcagggt tcagtcgttt catttcatgc cacactttac gcttgtaaga gggcaggtcg
   125581 gaaatgtatt cacagccgac ttttgcctgc atatccttaa aaatatcgtt catttcatca
   125641 ctccaatctg aaattttggc aagaaaaaag cagtcaatcc taagactaac tgctttgtgt
   125701 atatctggta ttagattatg aaattgagtt tatcaattct tgtacttcat taaaaaatct
   125761 ggataaatga aaaccatctg caacggcatg atgtatattc attgtaagag gcattatata
   125821 tctttctcgc tctaattcgt atttacccca agtaataact ggtgcaagaa atttcccttc
   125881 gtcaaaaaca tgaacatcaa aatgattgta ttttacccat ggcaaacaag atacatcaaa
   125941 aaagttcaaa ggttgatttg ctacgaatgc acgttccatt ttatgtttct ctctatctaa
   126001 cataaatcgt tcatgaaatt caaatatgct atcagaaaaa tctgtaacca tttttgtgaa
   126061 attctcatct tctttatgaa attcagcata ggacggggaa atatagtccc atttaattaa
   126121 attaccttta ttgtcccaac tatatttaaa ctcatcatgt tcattaacga cctttgaaac
   126181 aacccatatc atagctggat aaaatttcaa atcatggctt tttgaaaatt caattagatt
   126241 tgttacatca atatctacgg ttaagctcat aacgatacgc atatcatcaa tgtaactttg
   126301 aaacaattta cctctattcc atttttctaa atcaattttt gtatatttat attccatgtc
   126361 cattctcctt tacattttga aattcagtaa aatgcaaggc tctctggata acatttcact
   126421 ccatgcaagt ctattccatt aagccttgta tggagataat acaatacaca atttcataat
   126481 atccctcctt atccaataaa ccttagttta ttgttttcat actcagatta taccattcat
   126541 atataggctc tacaataaaa atcattatgc accaataatc ttattgaaca gctctaacag
   126601 tacatctttc acaccgccag cgttgaatac taagccgaca gcaataaggg caactaccaa
   126661 gaagccaata agttttgaaa actcacgctt gaaccctaag tagataccga taaccacaat
   126721 cgccataagc actaagctct gtgcatttga taaaaaccat tgatacaaat tttgtccgaa
   126781 attcatttaa ttgtcctcgc tttcttctaa ttgtttcatt tcatagtcag cttctttgcc
   126841 gatactcaaa atacacatca agactacgcc gatacccatt cccatagata ccagcaggaa
   126901 gtcttttact aattcccaca ttttttatca ctcctaactt tccaccaaat cttttgcagg
   126961 ggtcgtctgc tgtttgatta tcatttcatg cttttcactc aaagttgcct gcttttcaat
   127021 cgtttccata tagtcagtcc cgtttccctt atcaatcttt ttcagcattt tcaaggtagg
   127081 tgctacctgc ctttgtaccc accgcaatgt acggtctaag gtgtaaggct ctggctttgt
   127141 cgtcagcttc aagctctgtc tgttatcgcc gataaaccaa gcccagcggt cattgagttt
   127201 ccagtcattt tttcgcttgt ctggttcttc atcaacaaac cgcacatact ggttgatgat
   127261 agaaaaggcg gtctgttctg cgtcataata ggtcagcaaa tctcgtactg cataataggc
   127321 acgctcattt ctaagccgta tctcaaaacg gttgataatg tcggcttcat taagcggtgt
   127381 acccaacttg acgtactgct catagtcctt ttcatagata cagaaatata catctgattt
   127441 cagcgaacca agataaagag tgcgtcccat atattctctg tcgtcctctc tgtgcttgat
   127501 aagctcgccc gactggtaaa acttataact tctggacttt ccgatatatt cccgtttcct
   127561 gcatttttcc gcaagctctg gaatatccaa aatgcccgta tggtcgttga tagcaaggtc
   127621 gatacgcttc atcacgccac cgtctacgag tgcgtccatg aggaagtcat accagcttct
   127681 ttgctgtgcc aacaggtaac tttcaaactg cctgcaacca cgccccttta actctaaaag
   127741 gacacctttt tcttcgtcag ccgacgtata gataaagatg tcccctaaag agtaatgctc
   127801 cgtatagctg taatgtccgt aatcttcatg gagcatatag ttgatattca gttttaatat
   127861 atctttgatg atgtgctgta tatccagcgt gggaaaacga atttttacat aatcaaacaa
   127921 catggtaagc ggtgcttctg gattgaacct tgccagttcc ttatgcagag tttccagaag
   127981 ttcctttgac ggcttcattt ttccgctttc tatcttattg agatattccc ttgttatacc
   128041 agaagccacc gccagcctgc cttgtgagat accgtaagca atccgtttct cccgtaattc
   128101 ttttatccat tgttcttcat tcagaaccat acccccaatc tgtaaagtgt gaagttttta
   128161 ggggcgactt cacaaccgat ttttgctagg aaaccatgcc agaagcctta tgtttcctat
   128221 gttttttgtc tattgtctat ttgcaaacgt acccctctgt tagataccga ggggttttac
   128281 ctgctggcgt ggcttacgcc acaccagcaa cggctagtcc gtgccgtcgc ctttcgcttc
   128341 gcacgtcgcc gtcccgtcct gccttgcttg tgcaagagaa ccgatagtct tcaaaaaatc
   128401 atgtcctttc gggactaagg gcgtgtaaaa ttcgcttatc acgcttgttc ctacatcaca
   128461 atagccacga cccttgatac gcttctggaa aaactgcttt ttcacatcag aaccgaacag
   128521 cataccatat cctaactcgc tgatacgccc caatcctaca cggaaattga agttatctct
   128581 gataccgtcc gagaaatact ttgcgtctgg acgctggcag gcaacgataa ggaaataacc
   128641 tgcttgtcgc cccagcataa cgattttctt taactggcta agtaggctca cgctttcttt
   128701 cgttcccagc atttcaaaaa aagccacata ttcatcaaag ataagaaagc agggtggcag
   128761 tcccagatag gcgtagtttt cgcctgtctt gtagttcgag tgttgcttca tttcctcact
   128821 tcgttgtacc atgccctcat aaaaggaatt gacgcaatct atcatttctt ctttggtgtg
   128881 gtacacgttt cccatgactg ttcccaaatc tgcaaggtca gcgttctttg ggtctaagat
   128941 gtaaaggaca gcgttggtat gcagtaaggc ttcaatgagc gtcagcagaa agtaagtctt
   129001 accgccacca gtcccaccag caatcagggc gtgagggagt gcgtcatatt cccagacaag
   129061 atttttcatc agtctaagac agccgttttc tgcccgtact tcatcaatgg taatgcggtt
   129121 tgctatcata tcataaagca gggtatattc aatataaccg tcatgcagtg ttttgtcggt
   129181 tagctcacaa tacaagccac tttccaattt atcctctaac cgtaaaagct ggtcttgata
   129241 tttccccagc gtaatttcac agcggatatg aagcagtccc ttttccattt gataataaat
   129301 ctttggaaac cagacgattt tttcccttga tctgctttgc aggtcagtaa aaaaaccgct
   129361 gtcttgtacg gtatcggctt cataccactt attttccagt atcattcttg ccagcttttg
   129421 acggtgcagg agcttcttga aactgtcgta acagaagcga taatacagaa aagcgaccaa
   129481 tgcacaaaca ccagtcgcta tcagtatggt tatcaagttg taaggggata acgtcaagcc
   129541 tttttccaac aagctgaaat gttcccaatc ggtacgcatg agctgtttga tattcagtag
   129601 caggagaacc gccacgaata caaacagaag cgtccctatg gaaaagtgat agacaaggtg
   129661 cttgtcgctg gctctgatac ggtgtccttt gttccaaatc ttacgcataa atcaatcact
   129721 cctttctggg tacgaaaaaa gcagtcaatc ctaagactaa ctgctagtta cgatttattt
   129781 gaaatgtgaa atctttccgt atttttcgta tgaatattta agcatttgat aaatatcttc
   129841 tctaagaata tactggtatg tttctgagat tgtttcatac accggaatag gaattgcttt
   129901 tgatgaagtc ctttggttcg attttatcaa cactcttttt gctggcttag atactgtttt
   129961 atgaacccaa tccgaattca ataaacagtg tcccataggt gtaccagaac tgcaatatgg
   130021 ttgattttca ttcttaataa atctaagcaa taatttataa tcacttgaag ataagttatc
   130081 cacatctgtc caaagaaatt ctaaactctg ttgccattct tctgcttgtc tctgtttgtt
   130141 acgttgttcc acaccttttg aataattatg atactgtatt ttctgtacca accatattac
   130201 taattcgatg attagaaacc atacgcagaa taggaaaaca gcataccccc aaatagtgaa
   130261 ttttaccaat aacttattat ccgtaggtgt aacgtaataa gctataaaag aaaaaactat
   130321 tgcaataact gtcggtacta aatacttttc aagaaatatc tttaataaat ctaataactt
   130381 ttcactcatg catctatgcc ccttaattaa aaaatcacat taaaaatatt atacgatttc
   130441 ttaattgcag aggcaatcaa aatatatttg atgaactaat tattttttcg tttgtccctg
   130501 cggtgtatgg ttctggggat tgcctgcgtt ttgattgcct ttattcttca acacaatatc
   130561 ctctgccttt acataccagt ccacatctgc acccgtatag gtctttcttg atactgtatc
   130621 ggctacggga ttgacaagct ccacaactgc attgtacgga aattccctta acggtacttc
   130681 tggcggtacg gacacgggga taattccacc atgcagactg cacttcaaat catagatacg
   130741 ctttttaagc tgagtactcg gtgtcccgtc ctcattctgc aagaatacat cacgcaccgc
   130801 cgtaaatttt aattctccaa atgttttctc tttgtcaata acaaacccgt ttgataatct
   130861 cataaattct tcactccttt acttttcttc aactgctaca atatcatcag caactaacac
   130921 ataatcggta tgtcccatat ccccgattgc gtaacctctg ccgtataact tcggattgac
   130981 aagttttact ttctgctcat acttgaaatg cttttcacca gcctgcacgg gaatttctac
   131041 cacaacattt tcacctttct gtacgtcaga ataaaggtta tagcttcgtc tggctaaaac
   131101 cctgcggtta tttttatctc tttcaaagac tggctcactt tcgcctgcaa attcaagagt
   131161 tccaaaagac tgtgtcatat ctggcacgac atatttcatt tccatagtgt tttacctcgt
   131221 ttctttctat ttttgataag ttgattgatt gtgatttctt attctggcgg ttgggtaagt
   131281 accagcaatc ccccagatag taaagggtaa aatcaatgct tacgcaccct tgactatccg
   131341 tgttcttgca ggttgtagac agacaagcca gaataagcgg aagtctaccg tttgaccgct
   131401 tcggcggaga acgtgatttt tctttcatca taccgttacc gccttatgat ttcttcattt
   131461 tacggcgttt gtaaagatat gttccagcca gtccaccagc agacgcaaac aacatcacga
   131521 taaatgccat tacatttgta ctgtcgcccg ttttgggact gtcgctaggt ctgtttggct
   131581 tctctggtgt ctgtggtgtt tcgggtttct ctggttcttc tggcttttcc ttaaaggtaa
   131641 tcgtctgtcc ctcgtcctca atgtctttat gctcggtaac tttcttcggc ttgtctggat
   131701 tgcttaaatc gtataattcc tcaaaagtta caagctgttt gccgtcaagg gaagtagcgt
   131761 caaaggtaaa ggcaacttcc actttcatag tttcgctgtc agcggtaaag gtataatcac
   131821 tttccacacg ttttccattg ataagaagct ctgcattttc tgctttcaac atctgccagc
   131881 ctacaagttt atactttgta ccgacttcta agccctttaa ggttacggta tcaatgattg
   131941 taacgtcttt tcctgcttca agctctttgt tgccgtcctt gtccgtagca gttgtatgaa
   132001 ttttgatgat acgctctgtg attaaaacag tttgcccgtc gtcctcaatg tccttatgtt
   132061 ccgcaacttt cacgggttcg tctggattgc tcaaatcata caattcttca aaggtaacag
   132121 ggttcttgcc acctaaagca gacgcattga atgtatagga aatttccact ttcatttctt
   132181 cctcatcagc gacaaaggta taatcatttt ctacacgttt cccgtcaatg ataagctcgg
   132241 cgttttcttc ctttaacatc tgccagcctt tgagctgata ttttgtgcct tttgtaagtc
   132301 cgtctaattt gacagtatca acaatcgtaa cctcttttcc tgcaaggata gtcttttcgc
   132361 cgtccttgct ggttgctgtg gtatggatag agatttcttt ttcgtattca tcagtcaaag
   132421 tccctaaatc aatcacaaga ttatttcttg ataccacgat ttcaaaaggt gggataagct
   132481 caaagccttt gttactatca caacacattt cttcaattat gtaggtatca taaggtaacg
   132541 cacccttgct gtcgtctggt tcagaagtcc caaaccatac accgtcctcg ctggtctttc
   132601 ctgcgttggt attgtgcttg tgagaagccc agtcagcaga agtggagaat tgcccgttat
   132661 cgtcagttac tacgacatga ctttctcccg tcgtcttgct tgtgatccga aacggaacat
   132721 cagcaagacg cttgtgtgtg cctgcaccga tttttacgcc ctcaatatct ccacgcttaa
   132781 tctgattgta gatagaatgg gcttcgtcgg ttaagtccac gatttttcca ttttctgtga
   132841 ttgcaaaatc aatcggtttt gcaccgtctg tcaaatatcc gtcgggtgct tcactctcaa
   132901 cgatacggaa gtttccataa ggtaaaaggt cagcagaagt agaagcgaca ccctcaatat
   132961 ctgtacgaat agtttttacc acttcatttt tcttgtataa cttgccttca accaatactg
   133021 cattatcatt taaggaaatg atgtcaaagg cagtatcttt caaggtagca cttccttgtg
   133081 gtttcgtatc gcctgtttct aaatctcgtt tctggatttt cacaccgcca cggataacct
   133141 tgtctgatac ggaaaactgg ttacttccag tcaatacggc aaggtcgccg tcctcagtaa
   133201 tctgtgttac atatacgccc tttatctgtt cggatttatc gccagcctgc atatatgcac
   133261 cgtcaagtaa gtagcctttt ggagcttttg tttcctcaac ggttagtgtt cctaaaggaa
   133321 gaaccgcctt gccgtcctgc atatagaaac tgtcgccaga taccttgtat gcgttcgcta
   133381 attttgtgat gtagtgggtt gtctcgtcgc tgtcagtttc agcgattgtc tttgtaaccc
   133441 atgtacgagt agcttcggca gggagattgt ctttgttata gaagcctgca taatacttcc
   133501 atgtaaattt cgcacctgct agagaagcgt tcccttgcgg attgtctttc tgtgtttcca
   133561 tatcaatctt gaaaagctca atcaaagtat ccgttacctt tggtgtatca gatactttta
   133621 aggttgctgt ttcgccagct ttgattgtca atggatagac tgttttatcc actttatatc
   133681 ctgctggtgc agaaagctct ttgatatata ctgtccctgc tttgacttct acaacattcg
   133741 tatttccgtt ttcatcagtc gtaagggtgg caagctgttt tgtgcagtcc ttatcagaaa
   133801 agacaccata agttgcacca gagatagagt aatttccgtt accgtctgta atgctggtat
   133861 tactggaagt cttttgcagc ttcgcatttc cgacattcag cttcgcccag aattgtccca
   133921 attcctgccc ctcgccagag tagatataac cgccacattc atagcgtcct ttattttctt
   133981 tgacaaaggc ttttgcacca gcgaaaactt cgtcctgcgt agcttttggt atttcatcat
   134041 aagaagctcg cacgttgtcg cattgccagc caagatgtac gcttaatctc tgccagacaa
   134101 cacattgttc caacagataa acttgtttgt aattcaattc cttgtgagct tcgccatact
   134161 gtttgacata ctctaaggat aacgccacat ctgaaatctg gtcggcactc atgcgtgagc
   134221 ttgcgtcagt tctggtcttg taaccattct tgaaatctgt attgatgtca atacaatagg
   134281 cagtttcgcc ctcaactttc atcatgccct cattgaatgt agaaccgata gaaccgtcat
   134341 tcattacttt ttcaacgata ccgacacgct cttttgactc cgtccagtat tgcttgcttt
   134401 ctgcatgaac gggtgtagtc ggtaaagcag taacgatagt tgcaagagct aagaagcccg
   134461 tacacaatcg ttttaacatc tttttcataa atctaatgct cctttcattt tgggtataaa
   134521 aatagacgct catttctgaa cgtcttacat ttaaaaaggg atactatttt aacaagtacc
   134581 cctaaagttt agtatttaat tgtttgtgtt cccacactct atatcaacta ctaccgaaac
   134641 attgatatag ttttttatct ctttatttct gattttatcg ccctcgctcg taaagacgat
   134701 atgcttgaaa aagtgcctaa aattaaggat ttctacatag ttcgtctttg tagcaacaca
   134761 caagtctcca catgtgtaga atgagggaac atatctacag gttgtgcctc aacacattta
   134821 aatccgtgaa catttagata gtctaaatcc cttgctaaag tagaaggatt acaagaaaca
   134881 tagacaattc tttccggatt cattgaaaca atagtctcta ataccttttc gtcacatccc
   134941 tttctaggtg ggtctacaac tactacattg gcagtcttac cctctctata catcttaggt
   135001 acaatttcct ctgcctttcc aacataaaat tcagcattat gtatattgtt taatttagca
   135061 tttattttag catcttttat ggcatcatct ataatttcta ttccataaac ctttttagcc
   135121 ttttgtgcca aaaataaaga tattgtacct atcccacagt aaatatcaaa aacagtatca
   135181 gtatcattta aatttgcata ttcaagagcc ttatcataca atactttagt ttggacaggg
   135241 tttacttgga aaaatgataa tggtgaaatc tcaaacacta agtcacctat ataatcgttt
   135301 atttttccat ctccatatat aactatattt tctcttccta gaatagcatt cgtatctttt
   135361 tgatttacat ttacaaccaa agtcttaaat ccaggtatat tttccttaag cactgaagct
   135421 aattctttaa gatatggaag tttgtttcca tttgctacta atacaaccat tacttcttta
   135481 gttgtaaaac ctatttttgt tactaaatgc ctaatcaacc ccgtgtgagt cttttcatca
   135541 tatatactta ccttataggc ccttatatat gtttttatta ttttaacaat tttatcattt
   135601 atctcatgtt gtattacgca tttttctgtc gatattacat catgagtctt ctttttatag
   135661 aagccaataa ttggaatacc attattcttt tgtattggaa attgtgcttt atttctatat
   135721 ctatatggat tatccattcc tatagtgtca tgaacttcta catcctctaa cttacctatt
   135781 ctcgaaagta cttgtttaac ttcatttgtt ttcatttcaa gttgtttatt ataatctaag
   135841 tcttgtatct gacaccctcc acaatcccta agattctcac tacacactct tttcaccctg
   135901 aatggagact tttctattat ctcaacaata tctcctacag cataattttt ctttacttta
   135961 ttaatcctaa ctttaacttt atcctgtatt aatccgccct ctacaaaaac tgtaatacca
   136021 ttgtactttc ctactcctac tccgccttga ccaatgtcta ctatatctac aatatacatc
   136081 tcgtttttcg aaagcataaa tcaccctcca atcaatctat tatatttaaa tctttacaaa
   136141 cttttttctt taaatttata ttaaaatatt gctattaatt aaactatatt ttttactaag
   136201 ctacaatatt ttattttacc aaaaaaaaag gagcttataa agccccttag taaataaatt
   136261 tattattttt cttataaaac tctagttgaa cctctatata ccacacctct tgatgcatcc
   136321 acagttacaa cttctccatc ttttactaga tttgttatat cagttgcaga cacaataact
   136381 ggtatatcta aatttatacc tacaatagct gtatgtgatg tcattccacc attctcagtt
   136441 actacagctc ctgctttttc tatataattg ttcatttcag catcagtagc agtagaaaca
   136501 agtatgtcgc cttcattaaa gtctacacaa gcatttccat tctttattat acgaacttta
   136561 ccttctaccg tttgagtacc tacacctata ccttgcacga tttcttcgct tattacatga
   136621 acctttatta aattagtagt tccacttact cctactggta ctccagcagt tataactact
   136681 aattccccat tatctatata atcagcttgt ctagctgcct caattgcctt ttctataact
   136741 tcatctgtat ttcctgcaac agaagactta actggatata ctccccatgt aagagctaat
   136801 ttattcatag tcttttcatt atttgtagta gctattattg gagattttgg tctaaattta
   136861 gataccattc tagcagtata tcctgaagaa gtagatgtta ttatagctga tgcatttaaa
   136921 tctactgctg ttgtacaagt tgcatggctt attgcatctg ttacagtaac attgttagta
   136981 ccattttcct ttaataatct atcataatct aaagtctctt ctgttctttt tgctattgta
   137041 gccatcattt ttactgcctc tacaggatat tttccagcag cagtttctcc agataacatt
   137101 atcgcatctg ttccatcata tatagcattg gcaacgtctg taacttctgc tcttgttggt
   137161 cttggatttc ttatcataga atcaagcatt tgagtggcag taacaactgg ctttgctaat
   137221 tcattacatt tttttatcat cattttttga actattggca tctcttcagt tggtatctca
   137281 acacctaagt cacctctagc caccattata ccatcagaaa cttttaatat ttcatctagg
   137341 ttctctacac cttcttggtt ttctatttta gatattattt gtatatcagt tgcattattg
   137401 ttctctaata cttctcttat tgctagtaca tcagatgcct ttcttacaaa agaagcagct
   137461 atataatcta ttccttgact tattccaaac tctatatcac ttatatcttt aggagttatt
   137521 gctggtaaat ttatcttaac accaggtaca tttactcctt tatgattttt aactattcct
   137581 gaattttcaa caacacaaac tatatcttct ccatttattt cttttactct taagccaact
   137641 aaaccatcat ctattagtat agaatctcct gatttaacgt cttcagcaag acctttatag
   137701 cttactgtac acatttcttt agtccccata atatctttca tagttatagt gaacttttga
   137761 ccttcttcta aaaatacctc tgggtcttca aagttacctg ttctaatttc tggaccttta
   137821 gtatctaata atatagcaac tggcttattt aatttttctc taactttctt tgccatatca
   137881 attctttctt tatgttcttc atgtgaaccg tgagaaaagt taaatctaca cacatttaga
   137941 ccattttgca taagttgagt taaaacttcc tcactttgtg atgctggacc tagtgtacaa
   138001 acaatttttg tcttctttac attatttaac atatttgctc ctcctgagat attattccac
   138061 agatttattt ttaatactaa aacttatata gataatattt ttgccatctc ataagcttct
   138121 ttatcaaata ctttcttttg agctaaagct tcacttattt ctaaatcaat tattttgttt
   138181 tcttttattc ctacaactct agctgatttt ccatctaata ataattctac tgctcttact
   138241 ccaagtctac ttgctagtat tctatcagat acagttgggc ttcctcctct ttggacatgc
   138301 cccaatacag tgactcttaa atctgctcct gactcttttt taagttcctt ttctaaatca
   138361 ctagcacttc cgactccttc tgctaaaacg attatactat gtctcttacc tcttttttga
   138421 gtagtcttta atcttagagc aacttcatcc actgtaattt ctacttctgg tactattata
   138481 gtttccgctc ctcctgcaag acctgcatat aaggctaaat ctccacagtg tcttcccata
   138541 acttctacta tgttaactct ttcatgagat gatgatgtat ctcttatctt acctatagca
   138601 tctataatag tattcattgc agtatcaaat cctatagtat aatctgtata tgctaaatcg
   138661 ttatctatag ttcctggtat gcctatagct gggaatccta agtcactaag tttttgagct
   138721 cctgcaaatg aaccatctcc accaattaca actaagcaat caattttata ctttttaaga
   138781 atttttactg cttttaatct cccttcttct gttttaaatt cttcacatct ggaagatttt
   138841 aatatagttc ctcccctgtg tataatatct ccaacagaag ataagttcat ttcagttaaa
   138901 tcttcttcta gtaatccctt atatcctcta ttgattccat atactttgca tccataatat
   138961 attgctgatc ttacaaccgc tctaatcgca gcattcattc ctggagcatc tcctccgctt
   139021 gttagtaatc ctatagtttt cattttttac ctccttggat tttatgtcaa ttttttatta
   139081 taatcattgt tattgtattc taatggactt tttttgtccc tatatcactt tttaatccca
   139141 tcaagactaa aaaaattaaa tgtccttaaa tgtccatttt gtgatattat atcacaaaac
   139201 ggacaatatt tttcatatta ttataatata tttagatttt tatataaaaa atcaagcttt
   139261 tacttttatg ttatctttag gaagtaactc ttctaagtta tttataaatt catcacatat
   139321 acaagtcaat gccccggtca ttttatatgc tttacgttta ccatttatat tttcatccat
   139381 agggtataag tatatgctgt cattacctgg atattgtttg gctatttcta caatattatt
   139441 agttgtatcg gtatcagaca tactatctat tttcaaatac aattttttac cactttctgg
   139501 cttaatattt tctacatttc tagttcttcc tgaattgtag tttctatctg caaagtcagt
   139561 atcatcattt atatctttta tctctctagc tataagtttt gcattttcgc cttcttttat
   139621 acttaatgtt ccttttacat atattatatt atcttcattc aaaatgacat tatacttttg
   139681 taataattga ggaaaaacta ttatttctat agcaccatac aaatcttcta attcaataaa
   139741 tgccataatt tcatttcgtt ttgttgtttt aatagtttta gttacaatca ttccacccat
   139801 tataacatct gtttcattca tttgtaggta tgactcttct tcctctttta atgaatttaa
   139861 ttttccatta tccatagatg ttttttcttg tagttctttt tcaaattgtg ataaaggatg
   139921 tccacttaca tacattccca agacttcttt ttcaaggtta agtctctctc tttcttcgta
   139981 ctcttgcctt ttaggtaaac tgtatatttg ttgaaaatca ctatcttcct cactatctcc
   140041 aaaagcatca aataaagaaa tttgaccttg aacatttttc tttctatcca tagatacact
   140101 ttctaataaa ctttcataac cagccatcaa actagctcta ttttcactta tattatcaaa
   140161 agctccacat tttattagac tttctattac tctcttattt gtatcttttt ggtctaatct
   140221 tttgactaag tctactaaat ctacaaataa tccattagat tctctttcag cgattatatt
   140281 gtttattata tttacaccaa cattttttac agctgctaga ccaaatctta tattgtcgcc
   140341 ttcaactgaa aactttgaaa aacttttgtt tatatctgga ggtaatacat ctatttctag
   140401 tactttacat tctcttatat actcaactac cttatcagta tttcccatta cactggttat
   140461 caatgctgcc ataaattcaa ctggataata tgtttttaga taagctgtct catatgctaa
   140521 aaccccatat gcagctgcat gtgatttatt aaatgcatat ctagcgaagt ctatcatgtc
   140581 atcaaatatt ttattagcta tttcctcttc tacaccattt ctgatacacc ctgcaatttc
   140641 tatattacca tcttcatcaa atttaccatg aataaaatat tgtctttctt cttccatcac
   140701 gtccatcttt ttcttactca tggctcttct aactaggtca cttcgtccat aactataacc
   140761 acctaaatct ctaacgacct gcataacctg ctcttgatat accaaacaac catatgtaac
   140821 ttccattata ggctttaatt tttcatgtag atatgttaca tcttttgggt tgcttttatt
   140881 ttttatatat gcaggtatag aatccattgg acctggtcta aatagagata ttcccgctac
   140941 aatatcttca aaattgtctg gttttagctg tttcataaaa cttctcatgc cagcactctc
   141001 caattgaaac acccctagtg tatttcctga tgaaagcatt tcatatactt tcgggtcgtc
   141061 ataatccatc tttgaaaagt ctattttttc tgtgtagttt tttataactc tatttttttc
   141121 tattaaatca agagtatctc ttataactgt aagagttctt agcccaagaa aatccatctt
   141181 taaaagccca agttcttcaa gtgttgtcat agtaaactgt gttgtgattg catcttgatg
   141241 tttgtacaaa ggtacatatt catctacggg attttttgat ataacaactc ctgctgcatg
   141301 agtagaagca tgtcttagca ttccttctat ctgttttgat atatttatta tttcttttgt
   141361 ttccgggtct tggtcataca attctttaag attaggattt gtatctaggg ccttatctat
   141421 tgtcattcct aaagcaaatg gtatttcctt ggctaccttg tcaactttat tgtagcctat
   141481 atccaatacc cttccaacat ctcttattgc agcttttgca cccattgtac caaaagttat
   141541 tatctgggct acatggtcat caccatattt tctctttaca taatctataa cttcttctct
   141601 tctctcataa caaaaatcta tatctatatc tggcatggat atacgttctg gatttaaaaa
   141661 acgctcaaat aatagagagt actttattgg gtctatgtca gttattttaa gtgtatatgc
   141721 tactatagaa ccagccgcac tacctctacc tggtcctact ataatattat tttctttaga
   141781 aaaatttata aaatcccaaa caattaaaaa atactctaca taacccattt tttcaattac
   141841 atctaattca taatttaatc tctccagtat ctcattgcta ggattatcat atctctcttt
   141901 taatccatta aaacacaact cccttaaata agtttctggt gtatatcctt ctggaacatc
   141961 atacttagga agatgtatag tattaaaatc aaactccaca ttacacatat cagctatttt
   142021 cacagtattg tcaatagcct ctaatgcata tggaaataat tcttccattt cttctcttga
   142081 ttttaaataa aactcatcac taccaaatct cattctattt gggtcattta atgtttttcc
   142141 catttgaata cacataagaa catcatgtat tttcgaatct tctttattta catagtgaac
   142201 atcattagta gcaactagtg gtataccagt ctcttttgat aattttacta aaccagagtt
   142261 tacttctttt tgctcaggta aattgtgatc ttgaatctcc aaaaagaaat tttcttctcc
   142321 aaatatgtct ctgtagtcaa gagcaaattg ttttgctttt tcataatttc tattcattaa
   142381 agcacgtgct acatctcctg caaggcatgc agaaagtgct ataatccctt tgttatgttt
   142441 tttaagttct tccatgtcaa ctctaggctt atagtaaaaa ccttctacgt atgaagttga
   142501 aactattttt attaaatttt tatatccttc catattctta gctaacagaa ctaaatgtcc
   142561 ttgatatttg tcatagtttg ggtctttatc tctcaatcca cgtgcagctg tatagacttc
   142621 gcaccctata attggcttta ttccttcttt tatagctgtt ttgtagaaat ctataacacc
   142681 aaacatacaa ccatggtcag ttatagctat tgagttcatg tttagttcct tagccctttt
   142741 tataagtttt ttcaccctcg aaaacccatc aagtaaacta tactcagtat gtacatgaag
   142801 atgagcaaaa tctttgttca ttaaatcacc tcctgcttta taattttaat tttaccacaa
   142861 atatatgtac taaaacaaaa acagagactt ttatctcaaa ataggaatta acttcaacgt
   142921 ataccattat atgttataaa ttaatgctta ttctgagatt gtcccctcaa tttattgcta
   142981 tgattttttt ttcaaatctg ttgcaatttc ttctattttt ctaagtctat gattgactcc
   143041 agattttcct attggtggtt ctaacatctc tccaagttct ttgagagtca tatcctcata
   143101 ctcgattcta atcttagcta tctcttgtaa attttctggc aaactgctaa ttcctatagt
   143161 ctcttgtata agcttaatat tttctacttg tcttactgct gcatttactg ttttagaaag
   143221 gttagctgtc tcacaattta ctatcctgtt tacattattt ctcatttctt ttactatttt
   143281 agtattttga agacttaaaa gagcgtggtg tcctcctata atactcaaca aatctgatat
   143341 ttgttcactc tctttgatat aaacaacgtg attatttttt ctagccacaa ttttactatt
   143401 aaaacctaaa gagtttataa gttcttttag agaatctgca aactcctcat tattagttac
   143461 aaattccata tgatagttct tttctgggtc gcttatagaa cctccaccaa gaaaagctcc
   143521 tcttatgaaa gctctcttac atccttcatg cttaattaag ttctctgaaa ttttgtttat
   143581 agtaaaaaat ccttctttat cttcaagtat acctaacttt tttaataaca tttctgaacc
   143641 catttcgctt gttaccatta atacataact gttatttctc tttagcattt gattcttatt
   143701 tactgagatt gtagtattga tattaaaatt cttttttaat aatttaaata ctttacgggc
   143761 tattgaattt aactctgttg ttatctttag atttagcttc ttatatccaa caatttgtat
   143821 acttccccct gatttaacta gagctgacaa ttcagctata ttacaacatt cattcccaga
   143881 tataactctt gctagttcat ttttggtttc agttgaaaaa gacatatcta tcacctatta
   143941 actaattttt ctttaacctt ttttttattt cttgtaaggc aacctttatt atctcctttt
   144001 catcatcata cctagctaag tctactactc tatctaggtg gataaattta gcatcaataa
   144061 agccttcctc tttttgtgga atagtatcca tattctttgc ttgcatcaaa taccaaaaaa
   144121 ctgttttatg aactgctcta ttttcatccc agttttcttt gaatgtatag tgtatttcac
   144181 ctaaatattt caatatatct gcttttactc cagtttcttc acttacttca cgtaatgctg
   144241 cctcttggtt attttcccct tcttctactt ttcccttggg taacacccaa tctccattga
   144301 acttccttag taaaagaatc gtattgccaa acaggactac accaccagca ctaacctctt
   144361 ctctcatcga tgttcactcc ttaaaactaa cataatgata aggatttcta cacaattttt
   144421 taaaatcctt ttttactaac ttttgttgta attatgattt agggctaact caataactat
   144481 gttagatata tactttgcat catgtcttat ataattattt tttatttcaa ttaaattctt
   144541 ctctacagtt tttataccca tctcttttaa tttatctttt tgctttttat ctaacaagac
   144601 ttgctctgct ccatcttgtt tatataagtc aagcatttct tctggcaata tctcattatt
   144661 tgcgattaca taatctatta aattctcatc agtgtgttct actatagcat taacatgctc
   144721 taatacattg tacccttctg tctcacctgg ttgagtcatt atatttgcta tatatacttt
   144781 tggagctaca gacgatttaa tggcgtctac aatcccctct acaagtaaat ttggtattat
   144841 gcttgtatat aagcttccag gacccataat tataatgtca gcatcataaa tagatgcaat
   144901 aacatccttt aatggtttta catcttttgg atttaaaaaa attttatcaa tagagctttt
   144961 ttgaattttt gactcttcag gtatactgga ttctccattt attatattgc cattttttaa
   145021 tttggcaact aaatttacat cttccaaagt tactggtaaa actcttcctg ttatagcaaa
   145081 aatttcactt aatttatata cagctttttc aaagtttcca tacaacccat tcatagcagc
   145141 caaaaacaaa tttccaaaac tctgaccttt taaaagccct tctgtaaacc tatattgcat
   145201 aacttcattc attgttggct ctatatttgc aagtgctaat aaacagtttc ttatgtctcc
   145261 cggtgggagc attcctaagt cttctctcaa tacacctgaa cctccaccat catcagcaac
   145321 agttacaatt gcagttatat tttgcgtagt gtgtttaaga cctcttaaaa ataccgattg
   145381 accagtacct ccacctatca caaccacatt tggttctcta ttttcaacaa tagacctttg
   145441 aaatagtttt actttttcat tttttgcttt tttatatata aataacgata caattaatgc
   145501 aatccaacct aaaattccta caataataag taatttagcc atgtttgcct ccattatcgc
   145561 aacatagagt ctctatgttt ctttacaact ctatatccct tattagataa atcctccgct
   145621 ataagatttg ttatagtaac tgacctatgt cttccacctg tgcatccaac accaattact
   145681 agatgttgtt ttccttcctc tatatattga ggtactaaaa aatgaatcat atctaaaagt
   145741 ttcacataaa attcttcact gattttagaa ttcataacat aatctctaac ttctttatca
   145801 tcaccagttt tagctcttaa ctcttcaaca taatagggat ttggaagaaa tcttacatca
   145861 aatactaaat ctgcatcagc aagtatacca tgtttaaatc caaaagatac tacagaaata
   145921 gttaggtttg gattatcttc acctgaagaa tatattttct ttatttcttc cttaaggtct
   145981 ttaggtttca tgttagttgt atcaattata catgtagata actcctttaa aggttccatt
   146041 atctttcttt ccatttttat accttctgga atctgcatat cttttgccaa tggatgattt
   146101 cttcttgtca ttttatatct ctttaacaat acatcatcat tacaatccaa atataccatt
   146161 tcatattcat aattttcttt ttctaaataa tttaagcttt catgaagcgc ttcaaaaaac
   146221 tttctccctc ttatatctat ccctagagca actttatcaa tacttgaatt tggttgataa
   146281 cataattctg caaatttagt tatcaaagca ggaggtagat tatctacaca ataaaatccc
   146341 atatcctcta aagctctcat tgtctcactt tttccagatc ctgaaagacc tgtaactata
   146401 acaaatttca ttgctaactc ctccctttta tcttatgttt attatattat aatgttttct
   146461 actaacgata tatccagatt agagtcagat atagtcttca tagctagttc aaaatcacca
   146521 actctttctg gacaatgtgc atctgagcct attataaatt tattttctag cccttttatt
   146581 ttatttaatt gatttacatt caaaaaagaa tggctactat ttatctcaag tctagtattt
   146641 gtcttttttg ctgtctttgc tacttcttct atatacacat cgcctttatc tcctggatga
   146701 gtaattataa aaatatcatt attacttatc gcatttatta cagcttttgt attatattct
   146761 tttgcttttt cagttttaaa aatatagtta ttacaatgat ttaataagct tcttaatgat
   146821 gttggagtag aaccaaagtg atatccagcc ataatataat caaaatctct aataaattta
   146881 tcatccatat ctatatttcc tttatcatct aatatgttac actccatacc taaaagtata
   146941 tttatatcag tgtacttatc atttaaataa tctacttctt ctctcatttt gagaatatct
   147001 tttttcttta caccatatgc aatatgttta taactatggt cagatattcc tattgttttt
   147061 attcctttag aaatggctac ctttacatta tcctcaatag tccctttgcc atgactatat
   147121 aatgtatgtg tatgataatc agccagtatt ttcatttgtt aatcctctcc aagtattttg
   147181 acttcttctt ccaacataac cccaaacttg gcatatacag cactttttat aacatatatt
   147241 aaatccaaaa tatctttagc acttgcttct ccttgattga ctacaaatcc acaatgcttc
   147301 tcagatactt gtgctcctct taaagtaaga cctctcaatc cagtttcttc tattaattta
   147361 cctgcaaaat atcctgttgg tctcttaaat gtacttcctg cactagcaaa atttaatggc
   147421 tgtttagtta ttcttctcgt cgctaaatca tccattaaac tttttatttc atcataattt
   147481 ccttcttgta attccaattc tgctgataaa gctatatatc cgtttttcga tattatactt
   147541 tttctatacc caaattccat ctgttcattt gataattcaa atatattgcc ttccatatcc
   147601 atcagtctta ctgacttcac tatgtccttc atttcaccac catatgctcc agcattcatg
   147661 gctaatgctc ctcccaatgt gccaggtatt cctgatgcaa actcaaaccc ttttaattct
   147721 tgcttttgga gagctttccc taaaactgat aataaagctc ctgactgagc agtcatccta
   147781 gtatcattta tctcataaga attgaaatta tcagctagtt ctattaccac tcctcttatt
   147841 ccaccatctt taattaaaat gtttgaacca tttccaatta ttaaatacgg aatagattct
   147901 tcttttacca acttaagtac attttttaat tgttcttcag ttctaggtct aactaatata
   147961 tctgctggtc ctcctaccct aaatgaaata tgttttttca taggttcatc gacttttata
   148021 tcctctttac ttaatatatt taataaattt atatatatat cttgattatt cattgtattt
   148081 cctcccaaat tatactgaac tttagctgtc attattattt aaattacatt agtatatagt
   148141 attaactata ttcaataata tatgattttg cttatcatat ggattttata ttttaagctt
   148201 cttaattaca aactatattc aataaatata taataaagta aaaaaaaaaa aataacaaca
   148261 tataaaagaa tataaataat ttaaaaaaag catcaatatc actgatatca atgctttaaa
   148321 aggcaattta attcgtatta tttatctaac tatttttgac atagcaaaga taataaatcc
   148381 ctccaactac tatggaacct ccaacgatat ttccaagtgt tacaaatacc aaattagtta
   148441 taaattgaac catagttata tttgctccta atgccattcc cattggtata aaaaacatgt
   148501 ttgcaacact atgttggaat ccacataata caaatagcat tattactgtc caacatgaag
   148561 ccaattttga cattatatct tgagatgctg tagccatcca tacagctaaa acgactagaa
   148621 tattacaaag tattgctttt aaaaacattg atgctatagt tgaattaacc ttagcttctg
   148681 ccacagctat agcttttgta gctgcatctc ctgtcaatgt agaagaataa aacacaagtg
   148741 caactagcaa aattgaacct actaaatttg caaaataaac cagtccccag tttcttaaca
   148801 tttttcctaa tgttattttt ttgtccataa gtgcaatagc cattaaggtg tttccagtga
   148861 ataattctgc tcctgccact actacaagca taagacctac tggaaagacc atagcactta
   148921 aaaagctagc tacccctggg tctatcttgc caaaagtttg actaactatc atactcccca
   148981 atgccccaaa acctataaat gctcctccaa ataaacctaa tagaattgca ttttgtgtcg
   149041 aaatatttgc ttttttaatg cctgcactta tagttgcttg tgcagtttcc ccaggtgtca
   149101 agaatccttt actcataaat ccttccccct taaaaattat actttccctt gtctttttat
   149161 ggcaataatt atataataac aatatgatat ataataaatt ttattaacat aaaaaatata
   149221 ctatatactt atatatactt gtctcatata attatactat ttattatata acaactttgt
   149281 taatttcgaa ataatttata ttgaatttga aaaatttacc ttttgattat ttattttact
   149341 ttttaattat tgaggtatta tatataatag atatatgttt gtgttattat atataattac
   149401 ttattttaat aaatatttga aggagggaat tttatgtttg atatatcatt tttcgaaatg
   149461 tcaatatatg aaatagcagt tactacaata tatataatta atttcatggt tatactaaac
   149521 cttatcttta gagaaaaaag aaacataaat acaactttaa catggcttct tatattagta
   149581 ttgattcctg ctcttggatt catactttat atagcttttg gcagaaatat ttcaaaaaac
   149641 aatatgttta gattgaaaga aaaggatgat aagataatca aaagtaatat actagatact
   149701 caggttaaac tccaatctac atctgaaatt gattcagata tacatcaaca taaggatatg
   149761 atttatgcat tggctaattc aaataatgct cattatacca ataataacga tgtgtggatt
   149821 tatgctgaat ctagtcaatt ttttaacagt cttcttgaag aacttaaaaa agctaaaaaa
   149881 tatataaaca tacaatttta cattttcaaa gatgacaaaa tcggaactga aataatagac
   149941 attcttatag acaaagctaa agaaggtgtt gaagtaagac ttttatttga tgcagttggt
   150001 ggtagaacac taaaaaatag tacactttcc agacttaaag aaagtggtgt taaagttgga
   150061 agcttcttcc catcattctt gaaaattgta aactttaact taaactatag aaatcaccga
   150121 aaaattgttg tcattgatgg taaggtagga tttgtaggtg gatataatgt tggtgatgaa
   150181 tatttaggta gaaatccaaa atttggtcta tggagagata cacatactaa gcttactggt
   150241 gattgcgtaa ttgacctaaa tatgagattc atccttgatt ggagatatac aactaaagaa
   150301 gatttagatt tagaaaagta ctttatagaa gaagatacaa attctaatca tccttctgaa
   150361 aatattggga ttcagatagt atcaagtggt ccagatatat cagaacttga tgagattaaa
   150421 tatggttacc ttaaaatgat tcagaaagct agaaagtata tatacataca gagtccttat
   150481 ttaatacttg actcaacttt tatagatact ttaaaaatag cttgtttatc tggtgttgat
   150541 gtgagagtga tgattccttc taaacctgac catccctttg tatactgggc atcatattca
   150601 tatgctggag aacttttaaa gtttggagct aaaatctata cttatggtca aaatgcattt
   150661 ttacatgcta agacaatagt tatagatgac tctatatgct ctataggaac agctaatatg
   150721 gatatcagaa gttttgagct taatttcgaa gttaatgcat ttatgtactc ttcaaaaaaa
   150781 gcattggaac aaagaattat atttgaaaat gatattttaa attctaagga aataacatta
   150841 gatatatata attctaggtc tacttatata aaaatcaagg aatcaatttc aagactatta
   150901 tcagcagttt tataaatctt ttattttata aaaattttac attttggttt attttttaaa
   150961 gttttttata tgtattattt tttttttatt gaatttagct catttttttt atttttttta
   151021 actattctga attattttat attataatag actagtatag tttttatttt taataggtaa
   151081 cttttttgca ttgtttttat aaataaagaa attgttgtat attattcttt ctttattgtt
   151141 ttggttttgt tcacccacat aatgttgggg tcaactcatg gttaattatt ttatgaaaaa
   151201 taataacttt aaaaagaaaa gggggatttg ttatgtgcga ttttatttca cacaacaagc
   151261 aattatttga cgaactagat atatttattg actctcttgc aacaaaggaa ggtgcgttaa
   151321 tacaagttct acatgaagcc caaggtatat ttggatatct tccaaaagaa gttcaacttc
   151381 atgttgctag aaaacttgga gtagctcctg caaaggtata tggggttgtt acattctatt
   151441 cttattttac tacagaacct gtaggtaagt ataaaatcag tgtctgtcta ggaactgtat
   151501 gttttgtaaa aggtgctgac aaaatcttaa gtgcttttga aaaacagctt ggcataaaag
   151561 ttggagaaac tactagtgat tttaaatttt ctttagaagg tttaagatgt ttgggggcat
   151621 gtggtttagc tccagttgtt actgtaaatg gtaaagttta tggtaaagtg aaacctgacc
   151681 aagtaagcga aatattagat acttatagag aattagaatt gaattgttaa gaggggtgaa
   151741 taaataatgc gtaaagtaaa ttcatttgat gaattaaaag ttttagctga tgagctgaaa
   151801 cctaatctta gcttaagaaa aaattattct aaggaaaatg tattaagaag agaattactt
   151861 gtttgttgtg atactggatg tacatcttca aacagtctag aaatagttag tgaattagaa
   151921 aatgaaataa agaaatcagg aatccaagat aaagttagtg ttcgtttgac aggttgtttt
   151981 ggtttctgtg ctcaaggtcc tattgtaaaa gtttatcctg ataacgtttt ctacgtaaaa
   152041 gttgagccat ctgatgctga aaagatagtt caaagccact taattagaaa tacagttgtc
   152101 gaggaattat tatatgagga agaatcttta agtaaaaaag ttgaagaaca agaagaaatg
   152161 tctttctaca aaaaacagtt acgtatagct ttaaaaaatt gtggtcttat agacccagat
   152221 agtatagaag aatatattgc caatgatggt tatttagctc taggcaaatg tttaacttct
   152281 cttactcctc aagaagttat tgcagaggta aaaacttctg gccttcgtgg tagaggtggt
   152341 gcaggtttcc ctactggctc taaatgggaa gctgcttcaa aaaatccagc tggtccaaca
   152401 gataaaaagt ttgttgtatg taatgctgat gaaggtgacc caggtgcatt tatggataga
   152461 tctgtacttg aaggtgaccc tcatagtgta ctagaagcta tggcaatatg tggatacgct
   152521 ataggttctg atacaggata catatacata agagcagaat atccaaaatc tatagaaaga
   152581 ttaaaagtag ccatagctca agctgaaaaa tacggtttac ttggcgaaaa tatcttaggc
   152641 actggattta actttaaatt agaattaaaa tatggtgcag gtgctttcgt ttgtggtgaa
   152701 ggtacagcgc taatgcattc aattgaaggt agacgtggtg aacctagaat gaaaacttat
   152761 agttcttcta agagtggtct atggaaatct cctacttgct taaataacgt tgagactttt
   152821 gctaacatac ctgcaattat acttaagggt ggagattggt ttgccaactt aggtactgaa
   152881 gattctagtg gtactaaagt ctttgctctt ggtggaaagg tagaaaatgt aggacttgtt
   152941 gaagttccaa tgggtactac tttaagagat attgtatttg aaattggtgg gggaatccct
   153001 gaaggtaaga aatttaaggc tgttcaaaca ggtggaccat ctggtggatg tataccaact
   153061 gaacatttag acactcctat agactttggt tcattaagtt ctatcggttc aatgatgggc
   153121 tctggtggta tgcttgttct tgatgaatct gactgtatgg tagatatagc caagttcttc
   153181 cttgagttta ctgttgaaga atcttgtggt aaatgtacac cttgtcgtat aggtactaca
   153241 agattattag aaatattaac taaaattaca gaaggtaatg gtactctaca agatttagat
   153301 gacctagaaa accttgctga aactatacaa actgcttcat tatgtggtct tggtaaagct
   153361 gctccaaacc ctgttttaag tactcttcaa tatttcaaag atgagtatat agctcatgtt
   153421 gtagataaga aatgtcctgc tggtaaatgt cagaacttac tttcttactt tataacagat
   153481 gactgtaagg gttgtacaaa atgttctaga gtgtgtcctg ctggttgtat aacaggttct
   153541 gttaaggaac aacatacaat agatacttct aagtgtctaa aatgtggtgc ttgtatagat
   153601 aattgtacat ttaacgctat aatcaagaaa taacttattt ggaggaggaa taacaatgag
   153661 tttagttaat ttaactatta atggcaaaca cgtttcagca cctagtggaa cttctatctt
   153721 agatgctgcg aaattaataa atataaaaat acacaacctt tgtcatttac atatgaatga
   153781 aatagataag cttgacactt gtgcttcttg tcgtgtttgt atggttgaga cagagagagg
   153841 attagttcca gcttgtggaa cagttataaa ggaaggtatg aaagttcaga ctaatagtgc
   153901 taaagcatta aatgctcgta gaactattgt tgaattattg ttatcagacc atccacaaga
   153961 ttgttttgtc tgtgaaaaaa atggagattg tgaattacag actatagctg ctgatttagg
   154021 agtaagaaaa ataagatatc aaggttctaa atcttttgca ggtaaagata cttctactaa
   154081 atctttagtt aaagaccatt ctaagtgtat attatgtaga agatgcgaga ctgtatgtaa
   154141 tgacatacaa acagtaggag cattatctgg agttaatcgt ggatttaata ctttagttag
   154201 tacattcttt aactctgata tggttgaaac agagtgtaca ttctgtggtc aatgtatatc
   154261 tgtctgtcca actggagcat taacagaagt agataatgta cctaaacttt gggatgtttt
   154321 aaataaaaaa gaaaagacta tagtagtgca agttgctcct gctgtaagag ttgctattgg
   154381 tgaagagttt ggattagaac cagggtcaat ctctacagga aaaatggtag ctgctttaaa
   154441 agcacttgga tttgaacatg tatttgatac aaactttggt gcagatttta ctataatgga
   154501 agaagctact gaatttatag aaagaatcca aaaaggtgaa aatcttccta tattaacaag
   154561 ttgttgtcct gcatgggtaa acttcttaga gcacaattat ccagacaagt taaacttagc
   154621 atctagctgt aagtctcctc aaggtatgtt tggttctata gctaaaaact actatgcacc
   154681 taaaatatta ggaatcaatc ctgaagaact ttatgttgta tctgtaatgc cttgtgtagc
   154741 taaaaaatat gaagcttcaa gagaagaatt aagtgaatct ggaatactag atgttgacct
   154801 ttctataact actagagagt tagctaaaat gataaaagaa gctgctatcg atttacctaa
   154861 tcttcaagac caagattttg ataatcctct aggaaaatct acaggtgctg catctatatt
   154921 tggagcaagt ggtggagttt tagaagctgc cctacgtact tcatatgaga agataactaa
   154981 taagacttta gataatgtaa acttcactaa tgttagaggt cttaaaggaa ttagggaagc
   155041 aagtatagat gttgatggaa ctacagttaa tgtgtgtatt gtaaatacac ttaaaaacgc
   155101 tagaaagatt atggataagg tcagaagtgg agaatgtaaa taccatatca tagaagttat
   155161 ggcatgtcct ggtggatgtg ttggaggtgc tggtcaacct tatcaccatg gtaatactga
   155221 aatagttgat agacgtgcaa atgcgttata tgaaatagat agaaataagg ctattcgtaa
   155281 atctcatgaa aatcctgatt tacaagctat ttataaagac ttctttggag aaccaaatag
   155341 tgatgtagct cataaatacc ttcatactca ttactttgat aagagttgtg tctatggaga
   155401 gtgtccacaa gaatgtgctt gtgaagaagc taagtagtca taacaaagta taaaatttat
   155461 tcttaaaaaa ggattgtctt aaaatacttt tacgtaattt aagacaatcc ttattaattt
   155521 cacaaattaa attatatttc taaatagact tattctttaa ttaacctatc tattaattaa
   155581 agaatacctg ccattctcat aagttgtttt gcatttgtag ttttacatct tccatctttt
   155641 atcttatagt caaaatgaat tttatcgtct acatagtact ctgagaaatg atagtttaca
   155701 acttcaacat ctccactacc tgaaaggtca catagctcaa agtcatgtgt tgtcaccata
   155761 cttataaccc agggttttga taatttcttt accgcctcac ttgctccaat aattctatca
   155821 gcagagttag ttcccttaaa aatttcatct actagaacca acattggcag ttcttttaaa
   155881 ctatattgaa tcattgattt tattctaaga atctcagcat agaaagttga tattccttga
   155941 cttacatcat cttgtattct catagaagta aatatagcca tacaggtcgc atcaaaactc
   156001 ttagcgcata ctggagcacc tgcatatgcc agcactaagt ttacaccgat acttcttaaa
   156061 aatgttgtct ttccagacat atttgaacct gtgataatac aagtctgaga atttaattgt
   156121 atcgaatttg ctatgacact tttttctgct attaatgggt ggtatacctc ttcaactttc
   156181 aatcttggag tatcttcata ttttattact ggaaaacatg tattttcctt tacatgagaa
   156241 acaactgtta aacttattag agcttcaaat tctccaatag attcaaacca atctctaatt
   156301 tgatttccat atataccttt ccatcgctcc aaagcttctg cacaatgata gttccacatc
   156361 aaaacaccac aggcaattat atatagtatc tgattatacc ttaggtttac agcatttcct
   156421 attgaattta attgtttaac acctcttgaa actccacttc ccttagaaag tttatcttgt
   156481 aattctttca aatatgcact ctcaaacgtc tctttttcta aaacctcaaa cattttttca
   156541 tatacttgta tacttctact aaatgaaaat aatggagcaa gagtttgcat aagtcttgga
   156601 tatccaaaac cactaaaccc taactggatt ataaaaagta aaaaaacagg taaaacaggt
   156661 aaaaatccta acatacaaaa tataaaagat aaaattgttg cagttggtag accccaagta
   156721 aaaatatgca tccattttgg tatatacaca ttcttatttt ctccatactc tataaacgat
   156781 tctatactac tatctgaatt atttttttgc tctttaccaa ttatattact gagtgtttga
   156841 atatgaatag aaaaatcatc ttttgataaa agttctttta tagctctctg tctttctaag
   156901 attacattct catctggatt ttcattccac aaatatttgg ctaaaaaatt tttcccataa
   156961 gatgtattag ctacacagat atattgatac aatgatgctc ttccaaataa gtctaaatct
   157021 tttgcttgcg agttttcatc ttttaagtat tctttaccat ctattttaaa ttccttccaa
   157081 ccatctccaa atctcttaat atacttattt aatacttcgc tcttactttt aaaatatgtt
   157141 tcttcttctt ttactttact atgaataact aagagtgcta taaatattat tattgataaa
   157201 actccaacaa aaatacctac tatattttta ttgtaaaatc caatagcaaa ccctgctatc
   157261 actatcaaaa aagatattaa tcttgctgta cttatgttat ttgacttttt acttaagagc
   157321 aattcttttt cagtactact ttctaaaagt ttactaaaat attctattcc cataaaaaat
   157381 tccaactttc ttgttatata atgaaactca aatataaaat taatctagta ttattataat
   157441 ctaacactgt actttaaatt atccttatat aatatatctt attaataaac attatatata
   157501 tacaacttga ttttaattta taaggtgtag gacataatcc taatcaatat ttaattaaat
   157561 gatgtgtagt tcactattat tcagtactac ttagtatcga ttaattttga taatttttta
   157621 gtaaattctt gagctgcatc gtatcccatt cctctttgtc taaaattcat tgctgctact
   157681 tctaatatca tagcagtatt tcttccaggt ttaacaggta caactaattt ctctacatta
   157741 acaccaagta tttcttcata ttctttatcc agtcccagtc tatcataata cttagtttca
   157801 tcccaagctt ctaaatgaac tactaaatct atcattttag aatttttgat tgcccctact
   157861 ccatataaac ttctaacatc tattattcct attcctctta tctcaagaaa atgtcttatt
   157921 agttcaggtg actgacccac aagcatactt tcatctaatt ttcttatttc tacagcatca
   157981 tctgcaacta atctattacc cctttgaatc agttctaatg ctgtttccga ctttcctata
   158041 ctactttcac cttttatcag tacacctata ccataaatat ctactagcac cccgtgaatt
   158101 gttgtgtgtg gtgctaactt attatccaaa tagtttgaca gtctatttat aagtctagtg
   158161 gtatttctat ttgtgctcaa aagtattctt ttatattttt tagccttttc aattacatct
   158221 ggcttgattt ccaagtctct agaaattatt aacgctggta tttcatatga gaaaaatcta
   158281 tctagtactt cttctcgaat atgactatcc attaatccaa aaaaattata ttctgtcttt
   158341 ccaactattt gtattctttc atatgcaaaa taatcaaaat atcctgcaaa ctgtaatcct
   158401 ggtctattta tatcttgaga gtagacataa taatctacat catcaggcat gtatactact
   158461 tttaacttca actcttttat tatctctctt attgatactt tattgctagt ttccattaat
   158521 tttcttcctt tctaaaaaaa ttataaacat tatctgcaat gcttttattc attccatcta
   158581 cttctaaaag ttcttccata gtagcttttt ttatagcatc tacatcttta aagtgattta
   158641 ataatgattt ctttcttttt tcacctattc cttgtatatc atctaagata gattttgtca
   158701 aagctttatt tcttagactt ctatgatatg ttattgcata attatgaact tcttcttgta
   158761 tactagcaat aaatctatat aaattagttg ttttatctag ttctatttct ttttctttgc
   158821 atatcaatcc tttagttcta tgcttatcat ctttgtacat tccccaaaga ggtatatcta
   158881 catcattgag ttctagtact ttttttactg cactaacttg tccttttcca ccatccaaca
   158941 atatcaagtc aggtaaattt ccatgtttta atcttctatc tacaatttca gccatagaat
   159001 cataatcatt aggtccaata actgtcttta ttttatatct cctatattcc ttcttatctt
   159061 ttttagcatt cgtatacact accatagaac caatcgaatc tacaccttgt atatttgata
   159121 tatcataagc ctctattctt attggcaact tttctagatt caatatttgc tttaattctt
   159181 ccaatgctcc aatacttttt tcatattttc ttttattcat atcagaaaat ttttcaagat
   159241 attctacagc atttttccta accatttcaa ctaagctttt cttctctccc ttttgaggaa
   159301 ctcttattgt tactttttgc ccctttttag atgacagcca ttcttctaat atagaactat
   159361 cttctatctc atcttctata attaattctt taggtatata ctcttgttca ttataaaatt
   159421 gttttacaaa tgaacttaat atagaagctc ttggactatc cattacacct tctaatataa
   159481 aatgttccct acctacaatc ttaccatttc ttataaaaaa tacctggaca caagcttcat
   159541 tatgagctct tgccattgca accacatctt ggtttaagtc acttacagta gcatctattt
   159601 tttgtttctg tatcatctct tcaaggctct ttatcttatc cctatataca gcagcctctt
   159661 caaatctaaa gttcatagaa ctctcattca ttttttcctt taaaagttcc atcaattttt
   159721 cttctttacc agataaacac attataatct cttctatcat ttttccatac tcttctttag
   159781 aaacatttcc tgtacaaggt cctaaacatt tatttatgtg tagatttaaa caaggtcttg
   159841 tcttattctt tattgcttta tctatatcta ttttacagct tcttattgga tacgtactac
   159901 ttataagctc caaggtatca ttcacagcag ttatattggt atagggccca aaatactttg
   159961 ccttatcttt aagaactctt ctaactttta agattcttgg ataatcttca ttcgtagtta
   160021 cttttatata tggataagtt ttatcatctc taagcactac attatacttt ggtctgtatc
   160081 tttttattaa attacattca agtattaatg cctctaactc tgaatccgtt ataatatact
   160141 caaacttata tatattctta accatagatt ttactttaga tgtatggttt tttgaagatt
   160201 gaaaatactg ccttacccta ttttttagag atatggcttt tcccacatat attatatggt
   160261 cgtatttgtc tttcattaaa tatactccgg gctcagaagg taattttttt aaatgctctt
   160321 gtatatcaaa catctcgccc tccaaaacat taaattttat actaaaatta taccctaaaa
   160381 tatgaatttt aaaaagttat acaatttcca gtgctttaga caagttaaag cccatattcc
   160441 cttctataat tgatttgaaa acaattttaa ccatgaagag taatatggac tttactttgt
   160501 attactattt acaacttata tttgactaat ttacttataa caaaacagtt tatcgtatat
   160561 ctgctctaaa atttttcaca atttatataa cttaagaaaa atatttcttt aagaattgac
   160621 ctgtataaga accatcaact ttagatactt cttttggtgt tccagttgca actatagttc
   160681 cacccttatc tccgccttct ggtcctaagt ctattacata atcacaagtc tttataacat
   160741 ctaaattatg ttctatgact ataattgtat ttcctgtatc tgctagtctt tgtaatactt
   160801 ggattagctt gtctacatct gccatatgaa gtccagtagt aggttcatct aatatataca
   160861 aagtctttcc tgttggtctt ttactaagtt cagcagctaa ttttatacgt tgtgcttctc
   160921 ctcctgataa ttgagttgaa ggctgtccta atttaatata tgaaagtcct acatccatta
   160981 aagtttctaa ttttcttttt atatttggta tattttcgaa aaactcaaca gcttcttcca
   161041 cattcatatc taatatatca gatatagttt tatctttgta ttttacttgc aatgtttctc
   161101 tattgtatct ttcaccttta caaatttcac aaggaacata tacatctggt aagaaatgca
   161161 tttctatttt tattattcca tcacccttac aagcttcaca tctaccacct tttacattaa
   161221 aactaaatct acctttttta taacctcttg ctttagcttc attagtagat gcaaaaatat
   161281 ctcttataaa atcaaataca cctgtataag tagcaggatt tgaacgaggt gttcttccaa
   161341 taggactttg gtctatattt ataactttat ctatactttc aattcctttt atctccttat
   161401 gcttaccagc tctttgctta agtctattca ctttacttgc aacacctttg taaagtatat
   161461 cgtttattaa tgtacttttt ccagaacctg aaacacctgt tatgcatgta aacttaccta
   161521 atgggaactt tacatcaata tttttcagat tattttctga tgctttaact atttctataa
   161581 aacttccatt tccttctcta gtagtctcag gaagcaatat ttgtttttta ccacttaaat
   161641 attgacccgt tattgagttc tcattttcaa ttatttcatc taaagtaccc tgtgcaacta
   161701 tttcaccacc atgtatacct gcacctggac caatgtctat aacataatca gcttctctca
   161761 ttgtgtcttc atcatgctct acaacgatta aggtatttcc taaatctgtt agatgtctaa
   161821 gagtagttat aagcctatca ttatctcttt ggtgaagccc tatacttggc tcatcaagta
   161881 catataaaac tccaaccaat gcagaaccta tttgagtagc taatcttata cgttgcgctt
   161941 ctcctcctga taaagttcca gcttttcttg ataaatttaa ataatcaaga cctacatctc
   162001 ttaagaacat agctcttcct tttatctctt ttataatctc atgagctata aatctctgtt
   162061 tttctgtaag atttatattt tccataaagt caatcaattc atttacagat aagtttgtaa
   162121 cttccattat attttttcca tcaactaaaa cagataaaac ttccttttta agtctcatcc
   162181 ctttacactt tggacatggt ctctctgcca tgtattcttc aatcttatct ctcatgtaat
   162241 ctgaattagt ttctctatat cttctctcta agtttactat tacaccttca aagtatgatt
   162301 tataatttct agttcctcca aattttgact cataagtaaa ctctacaatt atattatctt
   162361 taccataaag taattcctcc acaaaatcat ctggtaaatc tttaaacggt gttgtcaaag
   162421 atacattaaa atgctctgct aaacttttta tcattttact gtaataagtg tcatcattaa
   162481 cacctgttga accccatgct gccactgcac cttgttttat tgataaatct ttgtttggta
   162541 ctactaattc tgggtcaact tctttacttt ccccaagacc attacaaaca tcacaagcac
   162601 caaagggagc attaaatgaa aacattcttg gagatagttc ttctatgcca attccatgtt
   162661 ctgggcatgc aaatttagtt gaaaaaagaa tttcttctcc atctattatt tgggctatta
   162721 caagaccatc agataactta actgcagttt caattgaatc tgctagtctt gattctattc
   162781 catctttaat tactattctg tccactacaa cttctatatt atgtttttga tttttattta
   162841 agattatatc atcactaact tcatagtttt caccattaac tctaactctt acaaatcctt
   162901 cttttttgat attatcaaag acttttttat gtgtaccttt ttgtcctcta acaattggtg
   162961 aaagaatttg taatttcgtt ctatctggaa aatctagcat tttatcaact atttcttgaa
   163021 tagtcatctg acttattttt tcaccacatg tagggcaata cacatctcct actcttgcaa
   163081 ataatagtct caaataatca tatatttctg ttactgttcc aaccgtagaa cgtgggtttt
   163141 ttgaggtagt cttctggtca attgagatag ctggtgataa accctctata tattctacat
   163201 ttggcttttc catctgacct aaaaattgtc ttgcataagc agatagactt tctacatatc
   163261 ttctctgccc ttctgcatat attgtatcaa atgccaaaga agacttccca gaccctgata
   163321 aacctgtaaa aacaataaat ttatctcttg gtaattctaa atctatattt tttaaattat
   163381 gttcttttgc tcctcttatt ataattttat cttccataat gttgttttta cctttctatt
   163441 tttccaattt ttcttctaat tgtttcactt tatctctaag ttctgctgct ctttcaaatt
   163501 gtaagttttg agcagcttcc atcatctctg attttaattt atctatatta gctcttattt
   163561 cgtctttatc atctgtatca gatattccat atacaacttc ttcctctgca accttagtag
   163621 cttctatact atctcttata tttttctgta tagttttagg aatgatattg tgctcttcat
   163681 tatataaatt ttgtatatct cttcttctct ttgtttcatc aatagcattt tgcattgagt
   163741 cagttatcct gtctgcatac ataattactc ttccattttc atttctagct gcacgtccaa
   163801 tagtctgtat taaagctgtt tcggaacgta agaaaccttc tttgtctgca tctaaaattg
   163861 ctataagtga aacttctggt atatccaatc cttctctaag taagtttatt cctacaagga
   163921 catcaaactt ccctaatctt aaatctctta ttatttctgt tctttctaat gtaactatat
   163981 ctgagtgtaa atatttaact tttatcccta tttctttaag atagttagtc aagtcctcac
   164041 tcattttttt agttaaagtg gttataagca ctctttcatt tttttctata gttttagtta
   164101 tttctcctac caaatcatct atttgattat ttataggtct tacttctaca attgggtcta
   164161 aaaggccagt tggtcttatt atctgttctg ctattgtctc tgagtgttga atttcataag
   164221 gccctggtgt agcacttaca aacaacattt gatttatatt tccttcaaat tcttgaaaat
   164281 ttaatggtct attgtcaagt gcagaaggta atctaaaacc attctctata agtgatgttt
   164341 ttctagacct gtctcctgca tacatacctc ttacttgtgg tatagtgaca tgtgcctcat
   164401 ctacaattat caaataatca tctgggaaga aatccattaa agtatatggt ctttctcctt
   164461 ctgaccttcc tgtaatatgt ctagaatagt tctctatccc ctgacaaaat cctatttcct
   164521 ttaacatttc tatatcatac ttagttcttt gttcaattct ttgtgcttct aatagcctat
   164581 cattttcctt gaaaaattta atttgttctt gaagctcgtt ttctatttct acaattgcct
   164641 tttcaattct ttctggcgtt gttacatagt gagatgctgg gaatataaca acatgatttc
   164701 tagtaccaac aatcttccct gttacataat caatttctgt tattctatct acctcatcac
   164761 caaaaaattc tattcttatt gctttttcat cattactagc tgggaatatt tctagtatat
   164821 ctcctctaac tctaaaggta cctcgtgtaa agtttatgtc atttctttcg tattgtatct
   164881 ctattaacct ttttattaca tcatctctgt ctctttgcat acctggtctt atagataaca
   164941 taagttcttt atagtctttt gggtcaccaa gtccatatat acaagataca gatgatatta
   165001 ttatagtatc tcttctctct aaaatagatg ctgtagcaga atgtcgaagt ttatctattt
   165061 catcatttat gcttgcatct ttttctatat aagtgtcact gtgagctaca tatgcttctg
   165121 gttgataata atcatagtaa cttacaaagt attcaactgc attgtctggg aaaaattctt
   165181 taaactcact gtaaagttgt gctgctagag ttttattatg agccattatt agggtaggtt
   165241 tcttaacttg ttgaatgata tttgccattg tgaatgtttt tcctgaaccc gttacaccta
   165301 ataatgtcga aaatttctca tttctattta tagaatccac tattgattta atagcttctg
   165361 gttggtcacc tgtaggtttg aagtctgatt ttattttaaa atccatagta tcactccttt
   165421 tttcgaacat tagttcctga catgtattat tatatcatac ctttataaaa ttgtttaagt
   165481 tattttaaat attttaccca tttaaatttt acttaaatct aaaacataaa aaaagacttc
   165541 tatctttgca atagaagtct ataattcatg gaaaataaat actttattca acttacataa
   165601 taaaatcaaa tgcttctttt tcaactccat ctaattttaa attaaacatt tttaatatag
   165661 ttgctgcatg tgctctcagg tctccttctt ctataaccac accaccttta atatttggtc
   165721 caaaagctat aaatggaggt ctattacctt tagtaggtaa atgaccatgt gtcgcaacag
   165781 caaacttgta atcttttata tctgaatctt ttataatact tccttcgaaa tcatttccaa
   165841 atgaaattcc ttcaagacct tcaattacca tttcaaaatc accttcaaga ccaaggttag
   165901 atgcttcctc tttggtaaaa atattctcta tgaataattc ttctttaaat tcttcaagca
   165961 gttctcttaa ttctgttaac ctatctaagt tatttactat tatttgagct gatattccag
   166021 aagaatttac ataggcatca aaatccttaa cttctccatt ttcaactttt ataaatccat
   166081 ttgatttaag caagacattt ggatttataa ctttatcaac tctaagatga ccatggtccc
   166141 caagtattat aaaatttgta tctttgtatg tacctgcatc ctttgtagcc tgaataatat
   166201 ctcctaacca tttatcattc atttttaatg ctttatctac ttcgtcatta aataagccat
   166261 aattgtgtcg tgtatggtcc aatgtagcta aatgtattag cattaaatct ggtttatatt
   166321 cctttattat atctactgaa cagtttactc caaataaatc catattgggt tctaatttcc
   166381 aatcgatata atgacaatgt ctattgtaaa taccgtccat tataacctta ctggaacttc
   166441 gttcaaaagt ttctcttggg tcatcttctc tactaggagc ccatatttct gcaatattat
   166501 aatctatatt tggatttgct cccattacag gccataatac actagaggta gttagattat
   166561 tttcttttgc tacatctata atagtttttg cttttatgtc ctttgagtac cagtaccagt
   166621 ctttattttc tttatttggg tcaaattttt cattatgata tataccatgt tttttaggat
   166681 atactcctgt aaccatacta gtatgacacg gatatgtcag agtgggataa acacaattta
   166741 tattttttac tatggagcaa ttttctagta tagatttaaa gtttggtaga ttttttacaa
   166801 attccaagtc tttttcaaat aaagaatcta ctgataatac tataaccttt gtcatttaca
   166861 ttacctcttc atttatatat tattgaatac ttttaatcaa cttacaagtc tatataatta
   166921 tttatttgtt ttatctatta ctgcttgcat tgcagaagtt cctttgctta ctacatcttt
   166981 tggatttgca tttaaatcag taagcccctt tttaatctca tccattagct tatcagttgc
   167041 ttccttgtat ccatttaaca ttggaagtgc aacagcatat tgtaattggt cagttgcaac
   167101 cttatattga ggtttttctt tatataatgt ttgtaacttt tctgagtttg ttgcatcttc
   167161 agttgttggt aagtatcctg ttgatgaact aaactgaacg attttatctg tttgtgtcat
   167221 ccattctata aattctgcac ttgcttcttt ttctttatct gttccacctt caagcataac
   167281 tagattagct ccacctgtag gagttgcgta tttttgattt tttggtaaga atgctgttga
   167341 tatttcaaac ttaccttctg tttgttgcat aagtcctgct aaatctgctg ttgatgtaaa
   167401 tatcatacct actttaccat ttacaaaatc ttgttttgct acgtcccagg cattataatc
   167461 ttctccagga ggcattttca ttattccagc tttcatcata tcttgccaga acttaactgg
   167521 tgcttgtcct gcctcattat taaatgctac ttttttacca ttagttattt ctcctccact
   167581 ttgcattacc atagcttcat agaaccaaat atctattggc gtttcaaaac cataagtatc
   167641 ttctgattta tttgtcattt tactagcata atccttaagc tcttcccatg attttggacc
   167701 tgaagggtca agacctgctt tagttgccat atctttattt atgtataata ttggtgtact
   167761 tctattaaat ggcataccaa caaacttatc ctcataatat gaatttgtta aaagaccaga
   167821 aaagaatctt tcttgatatg ttttatcaaa atatttactc atatctacta aagcacctgc
   167881 tgatgcgaat gtacctgttt gagttatttc taataatgtt acatctggtt ggtctttaga
   167941 tgttaaggct gcctgtagtt ttgttgcatt ttcatagtaa tctttctgtt ttaacatatt
   168001 tacttgtaca tccttatgtt cactattaaa ttggtcaacc attttttgag cagtttctcc
   168061 attagttcca cctaaaggag cccagaaatc tatcttcgta atattgctat cagtcttttc
   168121 tcctttagat gcatttgcat cattagaatt tgaacaccca actaaagaac ctaataataa
   168181 tgttattgct aatcctgttg ctaattttct tttaagcttc attttcatcc tccaaattta
   168241 gtctttaatt ttttatttta ttcctgaata cataaaagct tcttttactt ttttattcgc
   168301 aaatatataa acaagaatta ttggtaaaat tagaattata tttcctgcca ttattacatt
   168361 ccatgcagta attccttctg aagatttaag gagcgcaact cctattggta aagttcttat
   168421 tgcatctgta tttgtcatta ctaagggcca gaaataatta ttccaatggt atataaaatt
   168481 aaataatata aatgttatta ctgctggttt tgccatagga accattattc taaacattat
   168541 ttttaagtca gaagcattat ctagtttagc tgcttcaata atttcatctg aaatctgcat
   168601 aaaattctgt ctaagcagaa atatcccaaa tgaagatgtc ataaatggaa ttataagtgg
   168661 aacataagta tttataaatc caaacttact catcatcata tagactggta gaaaagttac
   168721 ttgtggtgga atcataagtc ctacaagcaa aagcccaaat agcatttttt cacctttaaa
   168781 tttaatctta gaaaatgcat atgctgctgg aaccataact aaaaattgta caattaaaac
   168841 acttcctgtt acaaatacac tgtttagcaa atatctaaaa aatggacctg aatgccatgc
   168901 tgtactataa ttttctaaca ctatatcatt tggtataata gtgggcggta attgcatcat
   168961 ttcttgtgga tttttaaagg atgtagatag catccatata aaagggaata taaatattgc
   169021 agataaaagt aatagaatta atatttctat tgattttgat gctatttttt ttatatcaac
   169081 tttgtctttt ttgataggtt gtataatatc cattgtctcc tccttttgga taaaccttat
   169141 aatatctact ttttctttat tgataatgaa ctttctttga taagagtcta aagttagcat
   169201 atgtagcaat cataactata gctaacaaaa acatactcgc tgcactcgct tgtcctatgt
   169261 catagtatat aaatccagac tcatatatat aataagataa catgttagtt gaacccactg
   169321 gcccaccttg tgtcattata cttatctcat caaatacttg aaaagatgca gttgttgttg
   169381 ttatcataag aaaaaatatt gttggtgata atagcggcaa tgtcacttta aagaaattcg
   169441 ttattttgtt tgcattatct aatttagatg cttcatatat atagtttggt atggatttaa
   169501 gacctgataa cactattaag atattgtatc caagagtctt ccatattcct attagaatta
   169561 gtgacattaa agctgaactt tcacttgaaa gccactttga tgttggtaaa tgtaatgtcg
   169621 atagtatcca gtttaaaaag ccatattgtg gctccataat ccaaagccac aatacagcta
   169681 cagatactag tgaaattaca tgtggtgtaa agattatact ttgcgttaaa ttgtgtatta
   169741 tagaattttt atttagccaa acagcaagta ctatggctag tgatatagat atagtcacca
   169801 taaaaaaagt ataaattgca gtgttcgtta tagtttgtat aaactctgga ttctttaaaa
   169861 gttctgtata attgtttaag cctacatttt caaaggttga actaagaaga ctaccagatt
   169921 tgaagcttag agatatcgtc ttaattattg gatagactat aaacaataaa gttcctataa
   169981 tagcaggtgt tatatataaa tatgctttat taaattgctt tttcataaat atctccttta
   170041 attttagaat acatactttt acatactttt acatcttcta ttctttctcc atttttatca
   170101 aaataatata aatctttttc taatacactt attcttaaag ttcttccaat atcaaatata
   170161 tcattttccg ttttgactct tatctctcta ttaagaacag ataaacaata tatagtttca
   170221 tttcccaaca cttctttagt cacaactttt ccaaataggc taaatacatc atcatttttc
   170281 ccatctatgt ttatactctc tagtgttgct ttttctggcc tgaatccaaa tttaatatca
   170341 ttttttatat ctagtatgtt catacaagga ctccctataa attgagctac aaataaattt
   170401 ttaggatttt gatatatctt ctttggggaa cctatttgca ttatctttcc tttgttcatt
   170461 ataactatct tatctgccat tgacattgcc tcaacctggt catgagttac ataaacaaat
   170521 gtagacttta gtttttgatg taattgtatt aattctgttc tcatttgatt tcttaattta
   170581 gcatctaaat ttgacaatgg ttcatccatt aaaaatacct ttggattttt aaccatagct
   170641 ctagcaagtg ccactctttg tctttgacct ccagataagt tgcctggttt cacatttaaa
   170701 tattctctca atcctactac atcaataact tctgttataa gtttttctct tttttctttt
   170761 tctacttttt tgtttttaag accaaattct atattttctc taacagtcat atgtggatat
   170821 aatgcataat tttgaaatac catagctata tcccttttac tagcatccgt ttttgtaaca
   170881 tcattttctt caatcttcaa cctacctgaa gttatatctt caagacctgc aatcattctt
   170941 aacgtagtag atttaccaca tccacttggg cctaccaata ctgtaaaaga accatcttct
   171001 atagtaagat ttaaattttc tataactgta ttttttttat tataagattt tgttacattt
   171061 tctagtctta tatctgccat ttttatcctc ccaaaatatt taatttaatt ctacgattta
   171121 cttatagatt aataatactc ttaatttgta aaggatatat taagacaaag tgaatatatg
   171181 gtaaacttat taaaataaag gttaaattat aaacattttt tgttaaatat actgaggtta
   171241 agatgatata cagcttatgt tagctataat tttctatatt tttcatattc atggtttgct
   171301 atcacaatgt aattttaatt tatgaagagt catataaaac tatttatttt ttatataatt
   171361 tgatttgaaa gtaaaaaaga cctctatggg ggatagaggt ctttaagtgg gggagattga
   171421 gtaatttatt tttgctatat taagttttac aattatatta tgtcccaaat ttacaaggtt
   171481 taaacataaa aaataaaact tttttaattt ttataaattt acccaaaaaa aattacgtgg
   171541 ctacgtccta ctctcccagg cagtttccca ccaagtacca tcagcgctag agagcttaac
   171601 ttctgtgttc ggaatgggaa caggtgtatc ctctctgcta ttgtaaccac ataatcttta
   171661 tgcttaatat ttc
//
LOCUS       DAFAZV010000002       144258 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFAZV010000002 DAFAZV010000000
VERSION     DAFAZV010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 144258)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 144258)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..144258
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.002"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(50..967)
                     /locus_tag="KOU88_000151"
     CDS             complement(50..967)
                     /locus_tag="KOU88_000151"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210078.1"
                     /translation="MITAFKTKEEREKEVLEKALNSFSGIQKDRARIYLTENKVNDRL
                     FLSNLLVKYKFEIRDNLKDMERIRDEIREYKSYLKQELGNKTKIKEYINYLEGLLDSC
                     ESLICAYGNALIPLFDSINKEFTKKEICQLIGANEKILDEYYEFMKKHSKEEMSKDFN
                     FIYELIFVHHGEYRWRKGRYKDFVDCPDWEMPLFNALWSHMDNFIENNKEIQESMHSV
                     FDEVFGDISYFMNGDGTMEKSVQEINIKELISNYRDYGNSTVVFQLKKKSIIDITINY
                     KLKRQRGDVLIYKVFDSEDNELGEVHKII"
     gene            complement(1045..1698)
                     /locus_tag="KOU88_000152"
     CDS             complement(1045..1698)
                     /locus_tag="KOU88_000152"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3210079.1"
                     /translation="MDKNKMLKTLVRKAQSGDELAFNDILNVLDKEIKINASIYAKYL
                     EGIFEKDDLIAEAQAGLWKSIMNYKIEIEYVSAYFQKVIKNNMLRLVNKSKTKKFTNE
                     ILVLNKNVDSNEYTELIEFIQDEGLLVDEVIIEKERAEEIEAEKKLQMKIVKRKIRYI
                     PQPQKEIIRMYLKGYDTEKISKKINKSYNAIYSSKYRAVQNLKEMCLPEISKYNITI"
     gene            complement(1703..2440)
                     /locus_tag="KOU88_000153"
     CDS             complement(1703..2440)
                     /locus_tag="KOU88_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012721384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210080.1"
                     /translation="MTTNLKEQDRHLETLELNQDTEYKCLKCKDRLFIETDEGFKECK
                     CRKLRIAENILKNSGVSEEFRKLKFDNFNYQVDSSVAKAFTKAIEYSNYFEQIREIRR
                     NSIIFMGQVGSGKTHLSLAIANSLMNRSISVIYMPYRDSMTLIKQNIMDEETYRREVG
                     KYKSAKVLLIDDLYKGNITNSDINIMFEIINYRYLNKMPLIVSTEKNFDELLEIDEAI
                     GSRLIEMSKNYLIELKGKRLNYRIYGG"
     gene            complement(2376..3311)
                     /locus_tag="KOU88_000154"
     CDS             complement(2376..3311)
                     /locus_tag="KOU88_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBK3210081.1"
                     /translation="MNFDNETYFHINFEDPFTRVPNAILDNKNLTYSAIGVVTQMLRF
                     QKSGSHKIYAKSLISYRKDSKSRISSALNELINEGFVIRSKIRNDKGQIKGYRYDIFD
                     TPQIKIEEKEDVKSQPCFNIPNTVNPEIGKPGSEKTGDSKTEIQFFGNIKENSIKENN
                     NTIITINKEQEESAYIKKYYETYIGLITPNNFIELAGYLDDGMEVDVIIRAIDEATSN
                     GVKNYRYIKTILNNWIESGVKTNLDLTEYQNEYEKKKRKSNSLGGVKNDKQGKRNSQT
                     KSTEFDFNSKETRINDNELERARQALRDIGVEPRY"
     gene            complement(3320..3637)
                     /locus_tag="KOU88_000155"
     CDS             complement(3320..3637)
                     /locus_tag="KOU88_000155"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210082.1"
                     /translation="MNVVKGCNKQLHVTLNSTCLQDNNLSWQAKGLHLYLMTKAENET
                     IYLEDLKNKSSNGRDSTANILNELIEKGYVSREIRRDALTGKVLGGYEYKIYEESLKN
                     IEK"
     gene            complement(3768..4010)
                     /locus_tag="KOU88_000156"
     CDS             complement(3768..4010)
                     /locus_tag="KOU88_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210083.1"
                     /translation="METARLIAIGQIKQAEKEISRLQGTKNNSSLMWWEAVKFASQNI
                     LEGLEHDIELEASTEFREFMIIQEELERDRPIDVQL"
     gene            complement(4213..4374)
                     /locus_tag="KOU88_000157"
     CDS             complement(4213..4374)
                     /locus_tag="KOU88_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210084.1"
                     /translation="MLSLDISKKNVMTLKKDGKFLADIVFKDIKTGKKISVGTLNKKS
                     AGQSNQHNK"
     gene            complement(4489..4740)
                     /locus_tag="KOU88_000158"
     CDS             complement(4489..4740)
                     /locus_tag="KOU88_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210085.1"
                     /translation="MSSYFITRGDVMKILQQFKPYKYDEEKNIEYDEKIIANQNTEVY
                     IVYPRISDEENRRRWKEFDEVAKEVAINIAMKKAETVES"
     gene            complement(4760..5575)
                     /locus_tag="KOU88_000159"
     CDS             complement(4760..5575)
                     /locus_tag="KOU88_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBK3210086.1"
                     /translation="MNNLQVIERNNERVLTTQQLADVYETDVRNISNNFNNNKDRFIE
                     GKHYFLLQGDDLKNFKGIHTEYENLKFTSKMYLWTERGANRHCKILDTDKAWEQFDNL
                     EESYFNKKKDTLITNQLSPELQMFKQIFDTVAKQEIEQKQIKQEITETKQEIQSIKDV
                     VTLNTTDWREETRRLLVSMSQNLGGNEYINTLRKESYELLCKRFNVDLKRRLNNRRRK
                     MAEEGVCKSRREKFNYLDVIQEQNYLIEGYVIVIKDMALKYGIPSDLSKNCNN"
     gene            complement(5613..5816)
                     /locus_tag="KOU88_000160"
     CDS             complement(5613..5816)
                     /locus_tag="KOU88_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007788738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210087.1"
                     /translation="MKKIDHDFIKKRRNTLNLSLQNVAKELGFKNASTYFKYETGQYS
                     IRADMLPKLSKILDCDIENFFTN"
     gene            5983..6357
                     /locus_tag="KOU88_000161"
     CDS             5983..6357
                     /locus_tag="KOU88_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210088.1"
                     /translation="MSVSQRIKYLRENMNMSQKELSEKANINTSVMNRIESGERAIRD
                     DELIVFAKIFDVSTDYILGLSDTEKLNIDESYEFIDSLNSPDDIKELIKVILSLDEET
                     RDKMLKIAKVFVTEKNIEHNDN"
     gene            6850..7065
                     /locus_tag="KOU88_000162"
     CDS             6850..7065
                     /locus_tag="KOU88_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210089.1"
                     /translation="MLKDLRILRGLTQKELANRTNYSREYISDLERNKYKNITIPTIV
                     DLSIGLEISPLLLACHFIDEELKKRDK"
     repeat_region   7242..7796
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7243..7270
                     /rpt_unit_seq="tttacataccacatagttaatataaaac"
     gene            complement(8085..8237)
                     /locus_tag="KOU88_000163"
     CDS             complement(8085..8237)
                     /locus_tag="KOU88_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210090.1"
                     /translation="MDNFLFNVLASLTASVVVYLISKLFKKAKSHSRTKSDLRVEFKF
                     IFKSKK"
     gene            complement(8387..9812)
                     /locus_tag="KOU88_000164"
                     /pseudo
     CDS             complement(8387..9812)
                     /locus_tag="KOU88_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861148.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp26"
     gene            10003..10824
                     /locus_tag="KOU88_000165"
     CDS             10003..10824
                     /locus_tag="KOU88_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK3210091.1"
                     /translation="MIISKKITAILVSFLIMISMVGCAPKESATEVAKKYLDSIEIKD
                     YEVAYNLLSKDSKESVSLEKFEEYQDTLFKLQTLKDYKLGEENKVEKYKYSNKEYTNL
                     VKIKETDTIKYITENKEDTANFDRYFIIEDNEYKLLWHKDFKRALSSNYVKIARSETE
                     KDEDKDYNKAAIDIKKAIEIDDKNPLAYYTQSYIYIELQRYDEALKSIDKYLEYLDKN
                     NEAYKIDASDAYNLRGVIFMSKSEFNKARESYNKALELNPDNEYAKTNLNDIKGL"
     gene            10949..12466
                     /locus_tag="KOU88_000166"
     CDS             10949..12466
                     /locus_tag="KOU88_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK3210092.1"
                     /translation="MSVAIYLRKSRADEEAEKQGEFETLSRHKSTLLKLAKEQNLDVI
                     EIKEELVSGESIIHRPKMLELLKEVEENKYDAVLVMDLDRLGRGDMKDQGIILETFKE
                     SKTKIITPRKTYDLTDEFDEEYSEFEAFMARKELKLISRRMQRGRIKSVEEGNFIGTS
                     APFGYDAVTTGRKERILVPNKDADVVKTIFDLYINEDMGCSKISKYLNNLGIKTATGA
                     NWYNSAITNIIKNKVYCGYIQWQKKDYKKSKNPNKIKTVKLRPKDEWIEAKGKHEPLI
                     SEITWKKAQNILKKNGHVSYGNQIKNPLAGIVICKNCGRPLVYRPYADHDYIICYHPG
                     CNKSSRFEFIEAAILKSLEDTVKKYQLKASDIDLDKNNKDSNIEFQKRVLKGLETELK
                     ELGKQKNKLYDLLERGIYDEDTFIERSNNISSRTEEIKDSIKTVKNRLSTVKKDNSKI
                     IEDIKTVLSLYHDSDSLGKNKLLKSVIDKAVYYKSKEQKLDSFELMVHLKLHEDQ"
     gene            12489..12773
                     /locus_tag="KOU88_000167"
     CDS             12489..12773
                     /locus_tag="KOU88_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3210093.1"
                     /translation="MCNEISLLDILGTEANYVLDEVELKVQVGKLYEQLNKILTPRER
                     EIVQLRYGLTPYGYKTQREIAQKLDISRSYVSRIEKKALKKLEKELVQES"
     gene            complement(12870..14534)
                     /locus_tag="KOU88_000168"
     CDS             complement(12870..14534)
                     /locus_tag="KOU88_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBK3210094.1"
                     /translation="MSKKKTPFLKKVGKRSWCIFTIILIIYSVLIYRLVDIQVLKGDK
                     YKQSVESQSVEKVELNSGRGIIYDRNNKKLTDTSKSQVLIVEKEKLNNNYKILELIKK
                     ATKMNDLDIYKAVQEQLTRPIIQIQTKNIDKSMKKELEKNGIMVEEKTMRYAKDGLLS
                     HTIGYIKEDDKSGQSGIEKSMDSVLRNSNEKYISAFKAGDAGNEKSLNILKGSVKTVD
                     NKDKDRHLKTTIDYNIQKKLEQILNKEENPTAAIISEASTGEILAMCSRPNFDQNDIS
                     KSLKGKNGEFENRVIKATYPPGSVFKMVVLFSALENGVIDENYTYNCTGKTKVGNTNE
                     ILRCNKRDGHGFQNLRQAFSNSCNPAFLDIAMKLGKEKILKSAEKLHLFEKVDIGLDE
                     EKIREAPKNISIRNLAIGQENIEFTPLQINQMTQIIANNGTFKPLYLYKSLVDNNMNT
                     IKTYKSSKKEELISPYVCTQVKEYMKSVSRIGTAKDLKDIEGGCGVKTGTAQSSLNKK
                     AIDHGWITGFYPEERPKYVITVLVEGTQKGNKSATPIFKEICESIK"
     gene            complement(14606..15853)
                     /locus_tag="KOU88_000169"
     CDS             complement(14606..15853)
                     /locus_tag="KOU88_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBK3210095.1"
                     /translation="MELNKVELLAPAGDLERLKIAITYGADAVYIGGEIFGMRSAAKN
                     FSKEDMAEGVAFAHERGKKVFVTVNIIPHNEDFLQLEDYLLELEEIGIDAVIIADPGV
                     LSVIKKVIPNMEIHLSTQANTTNYLSANFWYEHGIKRVVVARELSFDEISEIRAKTPL
                     DMDIEAFMHGAMCISYSGRCLISNYMTGRDANKGSCAQSCRWQYHLVEEKRPGEYFPI
                     YEDERGTFFFNSKDLCMIEYIPELIKSGITSLKIEGRMKTAYYVATVVRAYRMAIDEF
                     YRDPENWKFNPMWMEELKKGSHRHFTSGFYLNKPTTEDQNYQSASYVRNYDFIGIVRE
                     TEDEDGLIVVEQRNKMCVGDEIEVMGPYKETMFTKIEEMYNEEGEAIESAPHPRQIVK
                     LKLSVKVGKDYMLRKVIEEKVEE"
     gene            complement(15840..16514)
                     /locus_tag="KOU88_000170"
     CDS             complement(15840..16514)
                     /locus_tag="KOU88_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBK3210096.1"
                     /translation="MSNIVNDLVEDYIRVTLKEKEGFLKDLEIYAEENSVPIIHKEVS
                     DLLKVLLKVQKPKRILEVGCAIGYSSIFFATIIGKDADIITVERNEKMIEKAKENIKL
                     AGFDNNITILEGDAEEKLSQVQGEFDLIFIDAAKGQYKLFFDLVIDKLKDGGLLVSDN
                     ILYKGMVAHDDFVVRRKKTIVKRMRNYLDYICNCDYLSTSLVPIGDGVALSYKESKRG
                     DVDGIK"
     gene            complement(16686..17765)
                     /gene="mltG"
                     /locus_tag="KOU88_000171"
     CDS             complement(16686..17765)
                     /gene="mltG"
                     /locus_tag="KOU88_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBK3210097.1"
                     /translation="MNFKENRLKIAVLIIVILIILAGIFVFIQIGPYDKNNKKDVIID
                     VPSGASVGKISDILYENKLIKNELLFKLLVKVSNKAPSIKSGTYLLNQSYSNNDIISL
                     LVSGKIYQDGIKVTIPEGATSKEIIAMLVSKNLGDKATFENLIKKPQEFYDKFPYLKE
                     DGITSLEGFLYPETYYFNSKKQSEEDILSEMLKVFDSKYTDKFKKKQKELNMTLQEVM
                     EMASIIEKEAVLDKDRPIIASVFYNRLKVGMPLQSDATIQYIFEERKKIVTYDDLKID
                     SPYNSYKNKGLPPTPISNPGIKSIEAALYPEKTDYLYFVAKIDGGNNYSTNYQDHLKY
                     VKEYKEARDKQSKDTKATNKENTKK"
     gene            complement(17978..19303)
                     /locus_tag="KOU88_000172"
     CDS             complement(17978..19303)
                     /locus_tag="KOU88_000172"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBK3210098.1"
                     /translation="MRMYDIIKKKRDNLELSKKEINYFIENYSKGDIPDYQASALLMS
                     IYLNKMNKQETVHLTEAMMNSGDMINLSEIDGIKVDKHSTGGVGDKTTIALIPLVASC
                     GAPVAKMSGRGLGHTGGTIDKLESIPGFSTEMEISKFIDSVNKSKIAVCGQSAKVAIA
                     DKKIYALRDVTATVDNISLISSSVMSKKLASGADAIVLDVKTGDGAFMKTLEESFELA
                     KSMVDIGTGMNRDTIGIVTDMDEPLGFAVGNSLEVIEAIETLKGNGPKDLVELCEVLG
                     AYMLVLSKVAHDFEDGVEKIRESIKSGTAIQKLKEFIENQGGNKDVVDDYSLFKKSKY
                     KYPVKSTKSGYISKIKAEDVGVSAMILGAGRETKDDILDLSAGIILEKKVGDYVNEGE
                     VLAYMYYNDEQKLSLAKGRFIDSYSIVDSKIEKNKLIYGIVTKEEIKKF"
     gene            complement(19507..20319)
                     /locus_tag="KOU88_000173"
     CDS             complement(19507..20319)
                     /locus_tag="KOU88_000173"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBK3210099.1"
                     /translation="MFEKIAQSSKFINSKSNIKPKIGLILGSGLGDLANDIEDPVTIK
                     YSEIPNFPVSTVAGHAGQLVIGKLEGKEVIAMQGRFHYYEGYSQKEATFPVRVMKELG
                     VEILIVTNAAGGVNKEFKAGDLMLIRDHINFSGSNPLVGKNDDRFGARFPDMSDAYSS
                     KYVDVVKNCAKECNIDVKEGVYMFFSGPNYETPAEVRMAQILGADAVGMSTVPEVIVA
                     SHSNIGVIGISCITNMAAGILNQPLSHEEVIETTQKVKSEFMNLVKTTVKNL"
     gene            complement(20366..21538)
                     /locus_tag="KOU88_000174"
     CDS             complement(20366..21538)
                     /locus_tag="KOU88_000174"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBK3210100.1"
                     /translation="MSRVIWIVIDSVGIGALPDAEKFGDSKDVSTLGNIFKEYPDIQI
                     PNMRNLGIGNIDGIDFFESIKEPIGCFGKCKEMSQGKDTTTGHWEMTGIIVDKPFKTF
                     EHGFSKEIIEEFEKKTGRKVVGNKPASGTVIIDEYGEHQIKTGDVIVYTSADSVFQIA
                     ANEEVIPLEELYNMCKIAREIMMGDNAVARVIARPFIGKKKGEFVRTSNRRDYSLDPF
                     EPTVLDNIKESGLDVLAVGKIEDIFNGKGITDAIHTKSNMDGVDETLNYMKQDNKGLI
                     YSNLVDFDSKYGHRRDPEGYKKALEEFDSRLPEIMANMREDDILIINADHGNDPTYKG
                     TDHTREYIPVMIYGNKIKKGFNLGVKDTFADIGATVADILNVKLPKHGSSFKEDLF"
     gene            complement(21580..22494)
                     /locus_tag="KOU88_000175"
     CDS             complement(21580..22494)
                     /locus_tag="KOU88_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK3210101.1"
                     /translation="MDIIEGYIDYIKDKKKLSENTVASYFMDIKKYMEYINQKSIKLV
                     DIVENDIISYLIKLEKDNVSIATIARMISSIKSFHDYLFLNHICTNNPAKDIKKPKIK
                     KENINILTEEEIERLLNFPKLTTPKLIRDKAIFEVLYGTGIKVSELVEMNIEDIDLDI
                     DYIYCNSCCKNQRVIPLCDITKLYLEKYLKEARPKMAVEGEKSLFVSSLGQRFTRQGL
                     WKVIKKYSNLANIDKNINPTMLRHSFAIHLLNEGANIAVVSKILGNVNLSSLQVYLNH
                     IDKNVRREIKEKHPRNDVDVELQKAEAK"
     gene            complement(22506..23111)
                     /locus_tag="KOU88_000176"
     CDS             complement(22506..23111)
                     /locus_tag="KOU88_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein M"
                     /protein_id="HBK3210102.1"
                     /translation="MRRTYRKNDFRELNRQIIIIGLLFMMSIVVGSYINKILPGSSNN
                     ILNNINPAVEYYNLNISIKDTVIQNLKSDAIFMGSIALLSLFVVTIPAVLVAFVLKGM
                     SIGYTINSCILALKFKSIKMILIILFKNLIIIPCAIILALISLSYFKEMVYEFKKKNR
                     KNMQFLIKRYILNIIIIIALSLGLQLILNTASIGIIKFLAK"
     gene            complement(23179..23715)
                     /locus_tag="KOU88_000177"
     CDS             complement(23179..23715)
                     /locus_tag="KOU88_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK3210103.1"
                     /translation="MVLEEKTISSDRVYTGKVITLKVDTVEIPGQGYQKRELVEVGGA
                     VGIVAITDDNKVVLVKQFRKPIEKPIFEIPAGKLEKNESPKECAERELKEETGYSAKN
                     IKLIHKFFTSAGFSNEIMFVYLATGLTPGENNLDADEFLDVYEIELEEAYNMVLKNDV
                     EDAKTSIGLLLVKDMFKN"
     gene            complement(23717..24784)
                     /locus_tag="KOU88_000178"
     CDS             complement(23717..24784)
                     /locus_tag="KOU88_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3866 family protein"
                     /protein_id="HBK3210104.1"
                     /translation="MISKRVGIVESIVSQTETLDDIRVNINGEIQRAYNYPKISGTIN
                     IGDEVVLNTTAVELSLGTGGYHFVITNLNNIESTLTEGGHIMKLRYTPLQIKVDSVEE
                     QESIYHDKFANFKGLEGLSVVVGTLHSMLTPFAASFKRNNPNKKLVYIMTDGASLPIY
                     LSKNVDTLKEKKLIDSTITIGNAFGGDYECINIYTALITAKEILKADAVFVSMGPGIA
                     GTGTKYGFTGIEQGSILDAVKKLEGRAIAIPRISFADKRERHQGISHHSMTVFKEIVN
                     VNVDIPITIYDDEKLNFIKEQINLNGLDKKHNIIYIDNNKTKEDLDYFNLKVKSMGRN
                     YEQDEAFFKAASTAAYYLMEV"
     gene            complement(24789..25613)
                     /locus_tag="KOU88_000179"
     CDS             complement(24789..25613)
                     /locus_tag="KOU88_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBK3210105.1"
                     /translation="MKDYILYTILLLTGLFGTYAVIPLFKNLLINGNVLRPNYKKDMI
                     PVSMGIVFLPMIVINGIILAFFTTEFKDLAYIFMFMFGMISMFFAGILDDVIGNRDVS
                     GLKGHFKSLFKGSLTTGGFKALFGGFVGLIVSVAISKDIIDIIVNTLIIALSTNLMNL
                     LDLRPGRAIKAYLFIMVIIFLTLTGFVQVLPLLIVPNVLAYFNYDLKARAMMGDTGSN
                     VLGISIGMLISFGYPFNIRLGWLIFVVIMHIFTEKYSLTKIIEKNKLLNFIDKLGR"
     gene            complement(25621..26313)
                     /locus_tag="KOU88_000180"
     CDS             complement(25621..26313)
                     /locus_tag="KOU88_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3210106.1"
                     /translation="MDSYISIIIPAYNEESRIKYTLESILDIKQINEIIVVDDGSIDN
                     TAKVVSELENEKIKFFKLDKNRGKGYALNYGIKLAMKNADIIGFLDGDLGSSAKEVEK
                     LIVPILNGEADVTIAKFPPAKRKGGLGFVKGLAKNSVFEMTGVELDATLSGQRIFKRE
                     VLEKFDEIPFGYGVEVGMTIDILKYGFKIKEVLVNMTHNETGRNLKGFIHRGKQYYHI
                     KKVLGQKKKEWR"
     gene            complement(26337..27212)
                     /locus_tag="KOU88_000181"
     CDS             complement(26337..27212)
                     /locus_tag="KOU88_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter"
                     /protein_id="HBK3210107.1"
                     /translation="MHINMKYYIVTIGAIFIALGIGMLVGFNLNNNQQLSEQQANIIN
                     DLDDKFDILKEKNDKLDSDLASVNRDYEEAVNFINKNVDKILAGSLNGKSIGIISANE
                     NDDYTKNIEDIINKSNGSIAFNIILKENITNPEKLKEMSTKLGTDVKNANDAVNYIID
                     TLKKEDASDILTYLQELDVIKFNFIGDTYLKYDSVVIAGGNDAKDSTKQFEKIEKFVV
                     SKLKSENKYLVEVQNTGVKTSYVELYSKNKVATIDNIDEGIGSISLAILLQQGNIVGN
                     FGRLDTATSLLPSIK"
     gene            complement(27230..28351)
                     /locus_tag="KOU88_000182"
     CDS             complement(27230..28351)
                     /locus_tag="KOU88_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210108.1"
                     /translation="MRVEAPIKVDRKTKKLAKRVESGEIAVINHIDIDEVAANSLVEA
                     KIKLVINAAPSISGRYPNKGPGILTENNILIIDNVGEELFEELKEGETIEVVDGKIYR
                     KGKFLGAGEVLDKYEVSHQIKAAYENLAVELDRFIDNTIDYAKKEKGFILGEVEIPKV
                     KTNYANKHVLIVVRGQDYKEDLSTMLSYIEEVKPVLVGVDGGADALIEFGYTPDVIVG
                     DMDSVSDEALKKASEIVVHAYTDGRAPGLKRVEELGLDAVVFPAPGTSEDIAMLIAYE
                     YKAELIVAVGTHSNMIDFLEKGRKGMASTFLVRLKIGSKLIDAKGVNLLYRSKLKIKY
                     IWALIATALFPVLVVASLSPGVQQFIQLMQLKFRVLLQM"
     gene            complement(28764..29588)
                     /gene="spo0A"
                     /locus_tag="KOU88_000183"
     CDS             complement(28764..29588)
                     /gene="spo0A"
                     /locus_tag="KOU88_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcription factor Spo0A"
                     /protein_id="HBK3210109.1"
                     /translation="MGGFLVEKIKIVLADDNKDFCQVLKEYLSNEDDIDILGIAKDGI
                     EALDLVKKTQPDLLILDVIMPHLDGLGVIEKLNTMDIPKMPKIIVLSAVGQDKITQSA
                     INLGADYYIVKPFDFVVFINRIRELVSNRVTQVEPKPRPVQETQMTRSDFVKNVGNIE
                     TEITNIIHEIGVPAHIKGYLYLREAIKMVIDNVELLGAVTKELYPSIAKKFNTTPSRV
                     ERAIRHAIEVAWSRGKVDTINQLFGYTVHNTKGKPTNSEFIAMIADKLRLEHSMVK"
     gene            complement(29730..30788)
                     /locus_tag="KOU88_000184"
     CDS             complement(29730..30788)
                     /locus_tag="KOU88_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBK3210110.1"
                     /translation="MNKINKNFKNIWIILGAVSIFTMVIIFNKNCNVNKETQIEAFTI
                     KNHDKKFVYPMGNIIGVKANTDGVLVLGYEEEDVDYIGGIQIGDNIVKIDNKRIKNSQ
                     DVSEILNKIKKSKVEVTFERKNKYKTEVIETKKENGKYKLGLWVRDKISGIGTMTFYD
                     PSMEKFKAIGHAIKDSDTNELLKIKQGYIYKPEQLKIVKASNEKVGKIKGDFNDSNLM
                     GNFSNNSELGISGNITENHNKEFNVANKEKQLIEVGRPQDVKIGDAVILFEDKNKNIT
                     SYDIKIESIVYDKGNYRDMVIKVVDDKLLEYTGGIVQGMSGAPIIQNNKIIGAITHVF
                     RDNPKKGYGIFIDEMIKL"
     gene            30949..31389
                     /locus_tag="KOU88_000185"
     CDS             30949..31389
                     /locus_tag="KOU88_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3210111.1"
                     /translation="MKLNVRIADINNWHDLVSLSVDKSQLDYIESNALSIAESKFITA
                     WVPVGIYDENSLIGFAMYGRLEDDRVWLDRFMIDSKYQGKGYGKASLDFLVNHLKNEY
                     NCDELYLSIFEDNKMAIKLYKDFGFEFNGELDYGGEKVMVLKSN"
     gene            31450..31941
                     /locus_tag="KOU88_000186"
     CDS             31450..31941
                     /locus_tag="KOU88_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3210112.1"
                     /translation="MADKMAQNITLQFVEEKDLENLENVKLLFTEYSNSLNIDLCFQD
                     FNNELKTLPGKYKKPSGSLILAFVDENLAGCVALKKLEGKICELKRLYVRNQFRGLKI
                     GKILLEEIIEEAKKFGYTHMRLDTLPSMKSAQGLYEKFGFYDIEPYTYNPIEGARYME
                     LKL"
     gene            complement(32034..32900)
                     /locus_tag="KOU88_000187"
     CDS             complement(32034..32900)
                     /locus_tag="KOU88_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210113.1"
                     /translation="MNKKDTMHLIFTIVIFILLWYIVVTVSEINKNIESCSNKLDYLS
                     QEIMSTKSDISNTINEEMSKSYITKSIDLKVKKIEKKECVIDVDVQLSKLGKNGKVFF
                     MYKEDSDKWNETEMTKHGELSYACEIKINTGSEYDYKVVTSGAISESSDVQKLTKSDY
                     MPEQPIFNSGIRDNREYFIEIVENSNLFNHESEKSKNKVYDNIRLEKVDIIVNEGKKD
                     TIYKAKLAEGLDDGKTNNSNRNQVNYEVSFPKRDIDGIIYIKAKLTYNNGVEYTKDIT
                     EDITMGLQDLEK"
     gene            complement(33114..34793)
                     /gene="recN"
                     /locus_tag="KOU88_000188"
     CDS             complement(33114..34793)
                     /gene="recN"
                     /locus_tag="KOU88_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBK3210114.1"
                     /translation="MILELYMKNCALVEELRLNIDKNLNILTGETGSGKSIIIDALGL
                     CLGDKYDRSFLRKGTDKGLVEAVFFSDNRYLKKILEENDISMEDDNLLVITRLIYSDG
                     KSTARVNGRTVKVSLLKEIASTLIDIHGQHQNQALFNKDTHLKFLDLFGENELEEFKI
                     AYKNVYHKYSEVKKALNCLTENKDEMQIQREIDLLRFQINEIEAANLNKNEYEDLLKQ
                     REVYRNSEKIYNNLNSSYSKLHNGEYNVIDLIGLASKELNDISKYDSVLSEYSDTVER
                     IMYELQDISGEIRNYKDNIDFEPYELEQIELRIDEINNLRRKYGDSIDDIFEYYGKIK
                     DRLDEILNRDERVEQLRSKLMNIEEDLKIKASKLTKARIEVATTLEKILLDELKSLNM
                     KNVMFKVNFEKGPFTLDGVDDIEFMISFNLGEDIKPIYKVASGGEMSRFMLAFKTILA
                     DIDDIDTLVFDEIDTGISGIAAQIVGEKLSDIAKKKQIICITHLPQIAANADTHYCIE
                     KDTSNNRTFTNVSKLNESQRKNEIARLIAGNNITEKTIEHASEIIELAKKC"
     gene            complement(34813..35625)
                     /locus_tag="KOU88_000189"
     CDS             complement(34813..35625)
                     /locus_tag="KOU88_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family rRNA
                     (cytidine-2'-O)-methyltransferase"
                     /protein_id="HBK3210115.1"
                     /translation="MKKRIDLLLVEQGYFESRERAKKAIMAGLVFVDNQRCDKAGTEV
                     KEDCSIEVKGNPIPYVSRGGLKLEKAMKNFDLTIDGKVCMDIGASTGGFTDCMLKNGA
                     IKVFSIDVGYGQLAWKLRQDDRVVCMERTNIRNVTIEDTKQFADFASIDVSFISLKLV
                     LPKAKELVRHDGEVVALIKPQFEAGREKVGKKGVVREKSTHIEVIKMISDFSVENGFE
                     ILGLDFSPIKGPEGNIEYLIHLRNGNEGYEFDGETYNNKIVEVVEASHNLDK"
     gene            complement(35758..37623)
                     /locus_tag="KOU88_000190"
     CDS             complement(35758..37623)
                     /locus_tag="KOU88_000190"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBK3210116.1"
                     /translation="MYKYLDKVNSPKDIKNMSIEEMDLLAKDIRKFLVKSVSKTGGHL
                     ASNLGVVELTLALHKVFDSPKDKIVWDVGHQSYVHKIVTGRKDCFVSLRQFNGLSGFP
                     KENESPHDIFDTGHSSTSISIATGIACARDIKKENYSVISVIGDGSITGGMALEALNQ
                     LGYIDTNMIVILNDNEMSIDKNVGGMSKYLSSIIRNSTVEKMTDEVDKILNVTQTGEI
                     LSKTAHRFKDKLMYSFSPQDCSFFDSLGIRYYGPIDGHNTKELIDILRKAKHKKGPVL
                     LHVITKKGKGYRFAEEQPDKYHGVSKFDIKTGVTSAKVKSMSISVGEKLVDMANSNEN
                     IVAITAAMPSGTGLNLFESAYPKRYYDVGIAEQHATGFAAGLAKNGMKPYFAVYSSFL
                     QRAYDQVIHDVCITKKPVTFLIDRAGLVGNDGETHHGMFDLSYLNSIPNIVVMAPKDT
                     REMELMMDLSLKLDCPLAIRYPRGSSYYLDKGEYGEIVLGKYEVLDEGQDTVILCIGS
                     MVKHALEAKEILSREGINPTIVNARFLKPIDEGMLKALLKNHKNVVTIEDNIVTGGFG
                     SRINKFIIDNEYNVNILNIAIPEEFVKHGNIDELYDFVGLSPKSIADKIRKLVIE"
     gene            complement(37657..38094)
                     /locus_tag="KOU88_000191"
     CDS             complement(37657..38094)
                     /locus_tag="KOU88_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent PAP2 family protein"
                     /protein_id="HBK3210117.1"
                     /translation="MDFFSEIFNNGALGISLIACFLAQFIKIFTGKEKRIELSRILIS
                     GGMPSSHSSFVTSLATVVGIEKGFNSTDFAIITVLALIIMYDAAGVRRAVGKQATILN
                     QMVADIQHGKHIEQKKLKELIGHTPLEVWFGALLGIVTALILM"
     gene            complement(38124..39011)
                     /locus_tag="KOU88_000192"
     CDS             complement(38124..39011)
                     /locus_tag="KOU88_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBK3210118.1"
                     /translation="MEFKQCLKEKASFVEKVLKEYMPKEEGYQKTVIEAMNYSLSAGG
                     KRLRPILTLEACKIVGGNEDEAIPFAIAIEMIHTYSLIHDDLPALDNDDLRRGRPTNH
                     KVYGEAMGILAGDALLNYAFEVMLAGSINKENPEKYLKAINEIAKGAGIYGMIGGQVV
                     DVESENKQIEKEKLDYIHMNKTAAMMVGCMRAGATIGGANSEQMEEITKYAKNIGLSF
                     QIVDDILDIVGDEAKLGKKVGSDIENHKSTYPSLLGLDKSKEIAHNLIDEAKKSIEKL
                     SDDVDFLKGLAEYIIDREY"
     gene            complement(39014..39229)
                     /gene="xseB"
                     /locus_tag="KOU88_000193"
     CDS             complement(39014..39229)
                     /gene="xseB"
                     /locus_tag="KOU88_000193"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBK3210119.1"
                     /translation="MNLTYEEAYKRLESILSELESKNASLDESLSLYEEGISLYKHCN
                     KLLDDAKLKISKFNQLGIEEDFKIEEE"
     gene            complement(39231..40436)
                     /locus_tag="KOU88_000194"
     CDS             complement(39231..40436)
                     /locus_tag="KOU88_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBK3210120.1"
                     /translation="MKLRALDISEANSYIKRILINDPILSNLKVKGEISNFKVHSSGN
                     VYLSLKDETSKLNCVIFKSNFNRNLKLDNGVKIIANGYISVYERDGAYQLYINEIEIE
                     GIGNLHIEFNRLKEKLNKEGLFDPKYKIPIPKMPNSIGVITSPTGAVIRDIINVIKRR
                     YPKVNIKLYPVTVQGDKSAEEICEAIRFFNHMKNVDTLIVGRGGGSIEELWSFNDEMV
                     AREVFNSQIPIISAVGHETDFTICDFVSDMRAPTPSAAAEIATPSLDDINYKLGNIKS
                     RMSKSLTNQIELDQYRLETVFNKINNYLDSYTIKDKVIQLDKIYDKIIFGIENNLKLE
                     DEKLVKIGALLHNLSPLATMDRGYSITQKNGKVINSIKGLKIKDSIDIVLKDGNLECM
                     IDKIENKEG"
     gene            complement(40433..41503)
                     /locus_tag="KOU88_000195"
     CDS             complement(40433..41503)
                     /locus_tag="KOU88_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-sialoglycoprotein endopeptidase"
                     /protein_id="HBK3210121.1"
                     /translation="MKLGNNIIIGIDTSCYTTSIAAISLDKKVIFNEKIMLEVRDNSK
                     GLRQSEAVFQHINNLGILSDRIKSFKDKFNVEGVCSSKKPRPVENSYMPVFNVGHNFG
                     KLLSSIYGCRFYETTHQENHIEASLLNSKLKNNNKFISVHMSGGTTEILLTSKQDSHH
                     NVCDTNLGKIAKISIKKDDKSKLYNNFGYNIDIIGGSKDISFGQLIDRVGIKLGYKFP
                     SGKYLDENALNCNLKIESGLKTSVRDGYMNLSGLENQVNKIINDNGYNTNQKEYISKL
                     VLDSVVRNMFKSLVYLCETYNVNEVVFAGGVSASKYILRELSVKLRKKHIEAYFTEPQ
                     YSTDNAVGCAIIGLNNFLGERV"
     gene            complement(41487..41993)
                     /gene="nusB"
                     /locus_tag="KOU88_000196"
     CDS             complement(41487..41993)
                     /gene="nusB"
                     /locus_tag="KOU88_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBK3210122.1"
                     /translation="MKKDRAQKSTTREYIMKLIYQININKEDFETLEDKVDNFLKDNS
                     EHIINRYKELALQYSKNTNLKLEDTEIEDVIDKKYINTVCKALKENHDKIDELINKHA
                     KNWTVDRMPKVDVSILRLSVCEILYLDTPNKVSINEAVELAKIYCDDKSPKFINGILG
                     SVVDEIGK"
     gene            complement(42078..42440)
                     /locus_tag="KOU88_000197"
     CDS             complement(42078..42440)
                     /locus_tag="KOU88_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK3210123.1"
                     /translation="MEDNKFGQVKISNDVIATIAGLAALEVEGIETTATLTDKLLKNN
                     GVKIQIEEEDVNLDVMVTIKYGMSIPDTAFKVQENVKNTVETMTGLKVSQVNIHIQGI
                     SFKKDKVDKEEAKATKKN"
     gene            complement(42550..43239)
                     /locus_tag="KOU88_000198"
     CDS             complement(42550..43239)
                     /locus_tag="KOU88_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIAH-like family protein"
                     /protein_id="HBK3210124.1"
                     /translation="MKFNYKGRGFVIITLTAMLVVVGTVNYQLSKKSLLETSKEFKAY
                     EEAQLQKNNDESDSSKTEDSSNIDKQDGKESADIDIVDSKASKVKEKATETSKEIKAQ
                     LSSEKNMKKASYILDMKMNREKQRNELVQDLNEMINNPSTTEESRKEASNMKLNIVKI
                     QEKELQIENLLSTKGYEEALVYISDNKVNVVVNEAKLEKKDAAKIFDLVAEQANVKYE
                     NIKLTNNNSNK"
     gene            complement(43266..43820)
                     /locus_tag="KOU88_000199"
     CDS             complement(43266..43820)
                     /locus_tag="KOU88_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AG"
                     /protein_id="HBK3210125.1"
                     /translation="MLKNLNDKDKRKVYSLITIAGICVVSLVLLSCFPSSKSDKQVGK
                     TETNKNAEKQVTKEQEKDDLESKLTAILSKIDGAGDVDVMVTFESSEEIQPAFNSNNT
                     TETTEEKDAQGGERTVTTSSENKTMITSNSSDPVVIKTTEPKIKGVIVVASGASDPSV
                     KETLYSAVQTSLQVAGHQVEIYSK"
     gene            complement(43832..44449)
                     /locus_tag="KOU88_000200"
     CDS             complement(43832..44449)
                     /locus_tag="KOU88_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AF"
                     /protein_id="HBK3210126.1"
                     /translation="MLEGIKAWIVSVLIGAFIVNIVDMILPSSKIKPYVNLVLNFMFV
                     FIVITPVVGFFSKDMSLEDRILKSMGNYNKQYVDSTNALAKETGNNSLSKGYEDGLKE
                     VLKLKLDEYGYDLEDIELNGANINNIKIKEKNNSAKSNNSSNEENKNNSTKREEENIN
                     SNDKENSKQVFKKGTEYGLNLNEEKLKNDLIKVLDVSIEDIQIDK"
     gene            complement(44509..45714)
                     /gene="spoIIIAE"
                     /locus_tag="KOU88_000201"
     CDS             complement(44509..45714)
                     /gene="spoIIIAE"
                     /locus_tag="KOU88_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AE"
                     /protein_id="HBK3210127.1"
                     /translation="MKKRFLPMIIGFLFTFFFVNIFAIMIFANEVPSSEDKEYGETKN
                     SIDKYIDGQLDKLDINEIQDYINKEIVINDVNLKSFVKDLISGEKNILDLFNKDGLKI
                     LMFDEFKASLKVVAVILVLALLSSILKSLENSFSSGAVSQIATYIIFITMVSLTLIGF
                     KDVLQICYDAIDHTVGLMQVIMPILITFLLLIGFPITSTTLNPIFIGGVTFINVFFKN
                     FLFVSITVAFGILIINNLSKNIRLKRFFSFVKQINYVSIGAMFTVYLGLVSIQGLYVT
                     SFDKFSVKTAKFAIGNFIPVVGGFVSDSVDILLSSSQLIKNIFGGIGLILLVGICLLP
                     VIKILSVIVVYKLAAIIVEPVGEDGISNFLNEVANLMIIMLASVIAITVMFFVTVAIL
                     TSISVVSQG"
     gene            complement(45799..46185)
                     /gene="spoIIIAD"
                     /locus_tag="KOU88_000202"
     CDS             complement(45799..46185)
                     /gene="spoIIIAD"
                     /locus_tag="KOU88_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AD"
                     /protein_id="HBK3210128.1"
                     /translation="MEIMQLIGIAIISTTLCLVIKKDRPEIANFIAIITGVIILLSVM
                     FKLNFIVDSIQDLANKANIPTMYISLIIKLIGIAYLMEFAIQLCKDCGEGNIASKLEF
                     GGKIIVMSMSFPILLSIVEMVVNIIP"
     gene            complement(46201..46398)
                     /gene="spoIIIAC"
                     /locus_tag="KOU88_000203"
     CDS             complement(46201..46398)
                     /gene="spoIIIAC"
                     /locus_tag="KOU88_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018589775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AC"
                     /protein_id="HBK3210129.1"
                     /translation="MEISLILKVAGVGILISVLNMILEKTDRKDWAGLTTLAGVIIVL
                     GMVITEISDLFNTVRTMFQLY"
     gene            complement(46415..46936)
                     /locus_tag="KOU88_000204"
     CDS             complement(46415..46936)
                     /locus_tag="KOU88_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AB"
                     /protein_id="HBK3210130.1"
                     /translation="MQIKIIIIAFLIGSSYLIGEQIYKTYTRRHKQLNDLIRVLEILR
                     MDLSFGLYTLEEIFNRIGGNKEFCFWKFFYQISEGLHNEQSKTLEIIISENIDVLSKE
                     TYLGNKEIEELKNLILTLGKSDIESQQRMIDLSIENLKKQTYETKEDINKKGVLYKKL
                     VTFIGIGICIILI"
     gene            complement(46926..47894)
                     /gene="spoIIIAA"
                     /locus_tag="KOU88_000205"
     CDS             complement(46926..47894)
                     /gene="spoIIIAA"
                     /locus_tag="KOU88_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage III sporulation protein AA"
                     /protein_id="HBK3210131.1"
                     /translation="MNKLSDEIINSLSTTIREKVEKVSNNNLNIEEIRLRSQKPLILN
                     ANSKDYFYNQKTMTLDLNQQNSYVVTREDVEQTFQIICKYSIHSFMDDIKKGFITLRG
                     GHRVGLVGKAIVEDGQVKNIKHISSLNIRVSREIIGCSDKILSHIIKGKNQINNTLII
                     SPPQCGKTTLIRDIVRNLSNGNEDYGFKGLKVALVDERNEIAGAYLGVPQMDVGIRTD
                     IIETCPKDLGITMLLRSMSPNVIVTDEIGSEKEIKALYTALNGGIGLITTVHGDSIED
                     IQNRKELNRLLDKELFKKVIILSAKRGAGTIEKIYDLEEKRWYFAN"
     gene            complement(48118..50103)
                     /locus_tag="KOU88_000206"
     CDS             complement(48118..50103)
                     /locus_tag="KOU88_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HBK3210132.1"
                     /translation="MKNLCKISDDYLNSKLKYLKLLSKQYPSISKASTEIINLEAILN
                     LPKGTEHFITDVHGEYEPFVHVLKNGSGVIKRKIEELFSNTIRDSEKKMLATLVYYPE
                     QKLDLIIKQEENIDDFYRINIYRLIELCKYASSKYTRSKVRKLLPENFKYIIEELLHE
                     HVKSEHKEEYYKSIVETIVDIGIAKEFIIAISTVIQKLVVDRLHVIGDIYDRGPRPDI
                     IVDKLIEHHCVDIQWGNHDILWMGAASGEKTCIANALRISARYANLDIVEDIYGINLL
                     PLATFAIEMYKDDPCKEFIPKVNDQSVTTTEKSLMAKMHKAISIIQFKLEGEVIRRRP
                     EFEMEHRLLLNMINYDEGTINLKGKTYKLKDTYLPTIDKKDPYKLTMEERNVIDKLVS
                     SFRGSEKLQKHVSFLFSKGSIYLKANSNLLIHGCVPLNEDGSFMSMNIMGKEYKGKAL
                     MDKMESLAREGFFFKDKAEEKLYGMDIMWYLWTGKCSSLFGKDDMTTFERYFIAEKET
                     HKENKNPYFKLRENEMACKRLFEEFDLELDESHIINGHVPVESKNGESPIKANGKILV
                     IDGGFSRAYQKTTGIAGYTLIYNSRTLQLVSHEPFNSAEEAIANESDILSTTVVVEHK
                     AKRKMVRDTDEGIKIQEEIEDLKLLLMAYKKGLIKEM"
     gene            complement(50192..50731)
                     /locus_tag="KOU88_000207"
     CDS             complement(50192..50731)
                     /locus_tag="KOU88_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3210133.1"
                     /translation="MPTITLKNGVDVLIREGVREDAQSIIDFYNEVGGETHFLSFGKD
                     EYKISLEEQENAIESAKASDNSVKLIAFIDGEIVGIATIDSNQKAKGKHVGVLGIVVK
                     EKYWGIGLGKRLMLDLIEWCKSNGITKKITLVTNEENYNAIGLYKKVGFEVESILKKE
                     CYYNGVYTDLIGMSLLLGI"
     gene            complement(50937..52250)
                     /locus_tag="KOU88_000208"
     CDS             complement(50937..52250)
                     /locus_tag="KOU88_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK3210134.1"
                     /translation="MNEKNKMGLISIILLGINAVVGAGVFLLPGDAMKSFGVASIFVY
                     IFDMLLVLSMAFCFAEVAGKFNKNGAAYVYTKEAFGDFCGFEVGLMKWVIGCISWGAL
                     IVGFPTSLSAVWAPAGEPHIQKIIIVAMIVGLTIINLLGVSLSKIVQNVITVGKLIPL
                     ILFIGIGIFFIKGVNFTSSTMVPPGAGATEFGAAALLMFYSFTGFESIAVAAEDMENP
                     QKNIPIAIISVIVIASIIYILNQVVCVGILGDSLSSTSTPVADAARICFGNMGAGLVT
                     FGTLVSVGGICMCGAFVNPRSCVALADDKMLPRIFARKDKKGTPYVAIIATMLITIPI
                     ALSGSFAELAAISAVARFIQYIPTSLSVLVFRKKRPELVGTFKTPFGAVIPLIAVCVG
                     TWLLFQASMHQLIMGLGALAIGVPLYFIMKSYNRKVYGENLKKIV"
     gene            complement(52272..52997)
                     /locus_tag="KOU88_000209"
     CDS             complement(52272..52997)
                     /locus_tag="KOU88_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBK3210135.1"
                     /translation="MKPIIGILGNLIIMENGMFPGLERSYVNNDYINAVLKGGGSPVI
                     IPVNTDKEVIKKQIEMVDGVLISGGWDINPQLYGEETREETTFIYPEVDEFDLIAISI
                     ALELKKPILGVCRGLQILNVSLGGTLYQDNNLIEGSYIKHTQSSKRHVATHKVDVKEG
                     SILEGILGKQLLTNSYHHQSVNQLGKGLKAIAYSKDGIIEAIEKEDENFVVGVQWHPE
                     MMVDYCDKMEKLFKYFINICSNL"
     gene            complement(53032..53277)
                     /locus_tag="KOU88_000210"
     CDS             complement(53032..53277)
                     /locus_tag="KOU88_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBK3210136.1"
                     /translation="MKYKTTGTCATEIEFEVKENKVTNVNFIGGCDGNLKGLKVLVEG
                     MNIEDVIQKLKGIECKTKPTSCPDQLSLALENYMNIK"
     gene            complement(53628..55628)
                     /locus_tag="KOU88_000211"
     CDS             complement(53628..55628)
                     /locus_tag="KOU88_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3210137.1"
                     /translation="MKQSIAIVTDKITKLSSFLEENIRLVLGNYIDINHYYLEVLKEN
                     DKIQGDFVLVMNDDRLNSMRKHLVQDSKIIVIRRTLKENEIYGLFSIPNGTEVLVVND
                     TKETTLETISLFYKIGVKNLKFTPYIEGKIYKNIDIAITPGVKGKVPSYINKVIDLGN
                     RYIDISTFIEIINGLRIDVKEIRKNLMAYSESLISLDNGVKDNYRQLFLKIEEQDVIL
                     NLSKDGIIFTSADGIINTFNKEALKILGINENPQGKNIEDIISEDLNILLEDKEIIDE
                     VVFTNKKYINVNKKSIFSMGNKAGIYYNLQEITYIKKLEQNLTNKLREQGQIARYTFK
                     DIKTKNKNMVKCVELAKKISKSDLSVLIIGESGTGKELLSQSIHNASNRSNQPFIAVN
                     CAAVPDSLLESQLFGYEKGSFTGALREGKKGLFELANNGTIFLDEIGDMPPLLQTKLL
                     RVLQEKQVMPIGSHNVINIDVRVIAATNKNLLKMIREGKFREDLYYRLNVLPIDVPSL
                     RNRKEDIITLMNFFLKNNIRLSPEVITILEKYNWPGNIRELQNVASYVSLMCDSMVFR
                     DDLPPYIRVECANNYEDGFGYTRKEFEEILRILYERRESSSGIGRGFIIEKLIQEGIE
                     ISESKVRKVLSYLSECGYISSKSGRGGSQITSEGIKLYNNIN"
     gene            complement(55659..57377)
                     /locus_tag="KOU88_000212"
     CDS             complement(55659..57377)
                     /locus_tag="KOU88_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBK3210138.1"
                     /translation="MNFRLPKKRLPKKIIFICIVLISIILFIKYDQNGLKEREIINKG
                     KYMSESLVADKEYDEAKKVVKTSFESIPEKKYNKVYNEVWDMLKTISYVPDGTKIVID
                     SLEKMRESDVKLSDECRFNIEKRLASVYIMDNNYSKAVDLTVKSIKLAEKLGNNYEKA
                     RLDVDLASIFLKIGGYETGEKLIKDSFKIDIDEGEKNGMVRLYAIINLAEIYVEEGEY
                     DKAIEISSRIKDYKKFVNTDNYNDFDIMASIMQSNAYVGKNNIQKAKTFLEKADYLIK
                     SDRTVYILDKDMYYYMAMGNLEYKSENYNSAIDNYKKSLEISTKRKLTQEKIKNLNKI
                     LNIYEKQGNIESLNEYQKMLINEYKENKSIRDSETSFYIIDKVSNESKLFEKTKKEIK
                     YYKILFTVILIAILGSTFLYNRLKYFKAQNLHDGLTNVYNRKSFDIMYEKYREKDDNF
                     ALVMIDIDNFKLINDNYGHKFGDTVIKGITNTICVMLEQDDKVFRYGGEEFSVLIRNK
                     SGDEVADIIDSIRVAIANKKWNDDVTVTISAGVAHVSDSKDVLEEADKNLYKAKQLGR
                     NKVVYK"
     gene            complement(57603..58841)
                     /gene="fabF"
                     /locus_tag="KOU88_000213"
     CDS             complement(57603..58841)
                     /gene="fabF"
                     /locus_tag="KOU88_000213"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBK3210139.1"
                     /translation="MNKRVVITGLGCVTPLGTGKEEFWSNIKSGVSGIDKITNFDAST
                     YQTQIAGEVKNFHPEEYISKKELKRLDKFAQFAIVSAKLAVEDANLDLDKVDRERFGV
                     IIGSGIGGVEAIETQHKILLEKGNKRVSSLFVPMMIGNMAAGQVSIFLGAKGPNTNVC
                     TACASGTHSIGDAFKVIQRGDADIMVAGGSEAAVTGLAFAGFCNMKAMSTRNDDPKTA
                     SRPFDKDRDGFVMGEGAGIVILEDLEHALARGAKIYAEVVGYGLTADAYHMTTPAENG
                     EGAARSMNMALKDGNVPLEEVDYINAHGTSTYYNDLYETMAIKTVFGEKAYDLCVSST
                     KSMTGHLLGASGAIEAVVCAMSIEDSFVPPTINIQEVGEDLDLDYVPNQGKEKNIRYA
                     LSNSLGFGGHNATIVLKKYV"
     gene            complement(58870..59094)
                     /gene="acpP"
                     /locus_tag="KOU88_000214"
     CDS             complement(58870..59094)
                     /gene="acpP"
                     /locus_tag="KOU88_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBK3210140.1"
                     /translation="MFNKVVEIIIEQLGVEDKEITMETSLMKDLEADSLDAVEIIMAL
                     EDEFGIEIPDTEAENFKSIGDIVKYIEANK"
     gene            complement(59148..59897)
                     /gene="fabG"
                     /locus_tag="KOU88_000215"
     CDS             complement(59148..59897)
                     /gene="fabG"
                     /locus_tag="KOU88_000215"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBK3210141.1"
                     /translation="MINLTGQVAVVTGGSRGIGKEIAKKLASFGADVVINYTSKEDEA
                     LKTKNEIESMGVKCTSIKCDVSKFDEVNQMIDSVVSEFGKIDILINNAGITKDGLLMR
                     MKEEDFDRVIDINLKGVFNCTKAVTKPMMKKKYGRIINMTSVVGIMGNAGQTNYCASK
                     AGVIGFTKASARELASRNININAVAPGFIETDMTKVLSDDVKESTLANIPKKSYGKPE
                     DVANAVAFLVSDMSSYITGQVINVDGGMVMQ"
     gene            complement(59897..60847)
                     /gene="fabD"
                     /locus_tag="KOU88_000216"
     CDS             complement(59897..60847)
                     /gene="fabD"
                     /locus_tag="KOU88_000216"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBK3210142.1"
                     /translation="MGKVALVFPGQGAQYVGMAKDLYENNTVAKSVIDEASDVLNMDL
                     KNLMFNGNEEELSKTENTQPAMVTHSVAVLKAVQAQIDLKYNACLGLSLGEYSALVAA
                     DAIDFKDAVCLVKKRGKFMQETVPAGVGAMAAILGLDRNVLENVVKDIQGGIVEVANY
                     NSPGQIVISGENEKIEEAMVKCKEAGAKRAVKLNVSGPFHSSMLKEAGVKLASELEKV
                     NITKPKVDVVANVNADYYKNEGKDLLIKQVSSSVLWEDSIERLLNDGYDTFIEMGPGK
                     TLKAFIKKIASNKKANVNIYNIDGIDSLNEFVQNYRNGEI"
     gene            complement(60863..61792)
                     /gene="fabK"
                     /locus_tag="KOU88_000217"
     CDS             complement(60863..61792)
                     /gene="fabK"
                     /locus_tag="KOU88_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HBK3210143.1"
                     /translation="MNKICKILNIKYPVIQGGMAWVATASLASAVSNAGGLGIIAAGN
                     APKEAIKKEIVECKKLTDKPFGVNVMLMSPFVDDIIDLIIEEKVQVITTGAGNPAKYM
                     DRLKEAGTKVIPVVPTIALAQRMEKLGATAVIAEGTEGGGHIGELTTMVLVPQVADAV
                     NIPVIAAGGIVDGRGIAASFALGASAVQVGTRFICSEECSVHSNYKNLVLKAKDRDAI
                     VTGRSTGHPVRTLKNKLSKEFLKMEQNGATPEELDKKGTGALRFATVDGDIEKGSFMA
                     GQSAAMVKEITPCKEIIEAMVNQAREIMPAIEL"
     gene            complement(61901..62887)
                     /locus_tag="KOU88_000218"
     CDS             complement(61901..62887)
                     /locus_tag="KOU88_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBK3210144.1"
                     /translation="MNTKAGILGVGSYLPEQSYDNFHFEKIMDTSDEWISTRTGIKER
                     RFAKESEATSDLASKAALKAIECAKLNVEDIELIILATITPDMSLPSTACIVQDAIGA
                     VNATAFDISAACSGFVYGVTIAKQFVETGCYKNVLVIGAETCSKFLNYDDRTTAVLFG
                     DGAGAAVIGPVNEGGILSTHMGSDGKGKDCLKVPAGGSRLKASKETVEANLHTIEMAG
                     SDVFKFAVRKMAETSLRALEKANLNTTDIDYLVPHQANIRIIQASSKRLELDMKKVYV
                     NIDKYGNMSAASIPVALDEAYREGKIKKGDNVVLVGFGGGLTWGASVVKWTL"
     gene            complement(62913..63935)
                     /gene="plsX"
                     /locus_tag="KOU88_000219"
     CDS             complement(62913..63935)
                     /gene="plsX"
                     /locus_tag="KOU88_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBK3210145.1"
                     /translation="MKIVIDGMGGDNAPKSNVEGAVNAIKEYQVDLIITGDKDLLEKE
                     FSNYEFDRNKLEIVHTTEIIENEDKPVKAIRSKKDSSMVVALNLVKEGKADAIISAGN
                     TGALLAGGLFVVGRIKGIDRPCLCSAIPNVKRGMTLIADCGANADCKPKNLVEFAAMS
                     NIYSRKVLGLENPKVALANVGLEEGKGNDLVKRSYEEIKKLDLNFIGNVEAREVINAY
                     TDIIICDGFTGNILLKSAEGVALSVMSLIKETFMASTKSKIGALLIKDDLRKLKSFID
                     YSEYGGAPLLGLNGGVIKAHGSSDAKAIKNAINQGIKFSKGKVVEDINQFISKYNEEN
                     KNNEDE"
     gene            complement(63946..64503)
                     /gene="fapR"
                     /locus_tag="KOU88_000220"
     CDS             complement(63946..64503)
                     /gene="fapR"
                     /locus_tag="KOU88_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HBK3210146.1"
                     /translation="MKKKSKAQRQKELIDMLKTDPFYTDEELSSLFDVSIQTIRLDRM
                     SLNIPELRERVKSIAETQSSKVKTLGVKEITGEIIDLSVGRLGISMLEVTQDMIYSKT
                     NTLKDTYIFSLADSLAMAIIDAPKVIMRVANVKSFKLIEQQDRLIAKAEVYRNIDKKH
                     YVKVVINNKAQEQIFRGKFIFEELD"
     gene            complement(64710..64886)
                     /gene="rpmF"
                     /locus_tag="KOU88_000221"
     CDS             complement(64710..64886)
                     /gene="rpmF"
                     /locus_tag="KOU88_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBK3210147.1"
                     /translation="MAVPKRKTSKSNTKMRRAANSKMEATGFVSCPQCHEPKLPHRVC
                     PDCGYYKGKEVVSK"
     gene            complement(64911..65435)
                     /locus_tag="KOU88_000222"
     CDS             complement(64911..65435)
                     /locus_tag="KOU88_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBK3210148.1"
                     /translation="MKVSIEKINRKETDKIDLNFCEKIDTISYCDEIYKLVSPVNLKG
                     KVSKTNKGLYLDIDVNFTIVDNCSRCLKEVEIPLEYSIQGFLVKEEDYDEDEFEEFDP
                     FIFDGEEIDLIDIIEQTLDFNVPHKVLCSENCKGLCQVCGANLNEEECSCSEITNDEE
                     YIDPRFAKLKDLFN"
     gene            complement(65528..66724)
                     /locus_tag="KOU88_000223"
     CDS             complement(65528..66724)
                     /locus_tag="KOU88_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBK3210149.1"
                     /translation="MKILVLNCGSSSLKYQLIDMNNEEVLCIGLVERIGIEGSILKHE
                     KAGRDDKYVVEQPMKDHKDAIALVLEAVAHPEFGAVKEMKEIDAVGHRVVHAGEKFAT
                     SVVITPEVEEALKECIDLAPLHNPANIMGIDACKAILPDVPMVGVFDTAFHQTMPKSS
                     YLYGLPHELYTKYGVRRYGFHGTSHNYVSQRAAEILGKDIKDLKIVTCHLGNGASIAA
                     VDGGKCVDTSMGFTPLEGLIMGTRCGDIDPAILPFLMRKEGLDADGLDKLMNKESGVY
                     GMTGISSDFRDIEDAAKNGDERAQATLEAYVKKVQKYIGAYAAEMNGLDVVVFTAGVG
                     ENGKAIRADIASNMEFLGMKLDKEANDVRGKETVISTADSKVKMLLIPTNEELMIARD
                     TLRLVK"
     gene            67187..68467
                     /locus_tag="KOU88_000224"
     CDS             67187..68467
                     /locus_tag="KOU88_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBK3210150.1"
                     /translation="MNILGLIVEYNPFHNGHIYHLSKSIEKTNATHTVAIMSGNFLQR
                     GEPALFDKYTRAKIAVENGVDLVIELPTLFACQSAEIFSHGAITILNSLNCINSICFG
                     SEEGNTEILYNIAEILANEPNEFKLLLKKYLDDGLLFPTARANALFDYIHQDKKNNFI
                     QNYSKEQLSKTLNSSNNILGIEYIKNLIHLNSSIKPFTISRVQSEYNSEEIESDICSA
                     TAIRTSLKENTDLFHLKNVIPEKTYNILNEKIDNGFLPMFDDFFFDILKTIILRDMDT
                     LKEYFEVNEGIENRIYKDIFTSEFLHELQLAIKSKRYTLTKIKRTLNNILLGIKKSDM
                     QLIKNIDTIPYIRILAFNDKGREILKEIKNKSEIKIINKFSNISFSLDDTIFKTLISY
                     DIKATNIYNSIYYKNNKDLVKGPMDFYTHPIYVK"
     gene            complement(68730..70121)
                     /locus_tag="KOU88_000225"
     CDS             complement(68730..70121)
                     /locus_tag="KOU88_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBK3210151.1"
                     /translation="MYKLIDKKDIDFLIDTCGEENVLVGSDINEDFSHDELGGIEKYP
                     EVLVNVLETEQVSKIMKYAYKNNIPVTPRGQGTGLVGAAVAINGGIMINLCKMNKILE
                     VDYENLTLTVEPGVLLMTIGQYVQDRDLFYPPDPGEKSATIAGNINTNAGGMRAVKYG
                     VTRDYVRGLEVVLPNGEIINVGGKVVKNSSGYSIKDLLVGSEGTLGIVTKAILKLLPL
                     PKKSISLLIPFPDLSMAIETVPKIIKSKSIPTAIEFMERDVILAAEEFLGKKFPDNTS
                     DAYLLLTFDGNSTEDIEKEYEKVANLCLENGALDVFISDTQERNDSIWSARGAFLEAI
                     KASTTQMDECDVVVPRDKIAEFIRYTHELQDKLKIRIKSFGHAGDGNLHIYILKDGMD
                     DNTWKIRLKETFDYMYKKSRELSGQVSGEHGIGYAKKEYLHESNSDAYMMLIKNIKLA
                     FDPKNILNPGKIY"
     gene            complement(70132..71352)
                     /locus_tag="KOU88_000226"
     CDS             complement(70132..71352)
                     /locus_tag="KOU88_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBK3210152.1"
                     /translation="MSKIVVNQDKITDLKRILEICPFGAIEEKSGIVEISAGCKMCKL
                     CVKSGPKGAFEFIESSKVQINKDEWRGIAVYVEHHNGNIHPVTYELIGKAREMASKIK
                     QPVYCVFVGKDIKDKCSNLISYGVDEVFVYDEDEFKDFRIEPYSKAIENFIDKIKPTI
                     VLVGGTTLGRSLAPRLAARFRTGLTADCTILDIQSNTDLDQIRPAFGGNIMAHINTPN
                     NRPQFATVRYKIFSAPEKIENTTGKITLCKVEKKELKSKIKVLSVKEKNKEVGLEEAE
                     VIVVASRAIKKQEDMEMIYKLADKLNAQVAGTRPVIEAGWIDAKKQIGLSGRTVKPKL
                     IITCGVSGAVQFVAGMQGADYIVAINKDDKAPILDVAHLALIGDIYDIIPKLIEKIEN
                     NKDNNQKYMASAAK"
     gene            complement(71366..72154)
                     /locus_tag="KOU88_000227"
     CDS             complement(71366..72154)
                     /locus_tag="KOU88_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003402402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBK3210153.1"
                     /translation="MEILTCIKQVPGTTSVEVDETTGVLKRDGVDSKMNPYDLYALET
                     ALRIKEDKKANLKVLSMGPPQAKKVIEESFMMGADEGALISDRRFGGADVLATSYTIS
                     QGIKKMGKVDLIICGKQTTDGDTAQVGPEVAEFLDIPHVTNVTKLIEVKDESIVVEID
                     MPNDLQVCEIEYPCLITVEKDIFQPRLPSFKLKLNTKDREIPVYSLDDFEDKNENNYG
                     LNGSPTQVVRIFPPKPNTDKNIVRGNADELSFALVNKLEELKLV"
     gene            complement(72171..73445)
                     /gene="larA"
                     /locus_tag="KOU88_000228"
     CDS             complement(72171..73445)
                     /gene="larA"
                     /locus_tag="KOU88_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-dependent lactate racemase"
                     /protein_id="HBK3210154.1"
                     /translation="MVKLKVPYSKQGMILEIPDERFLGVLESKSDNYIEHKTQEEIVE
                     ESMNNPIGSNSLEELVKGKKNVVIITSDHTRPVPSRITMPIILRRIRNVNPEIDVKII
                     VATGFHRPSTREELIYKMGEEIVDNEDIVMHISTDDKSMCKVGILPSGGDLYINKLAY
                     EAELLIAEGFIEPHFFAGFSGGRKSVLPGIASAKTIMYNHCSDFIDSDNSRTGKLNNN
                     PIHEDMVYAAKVAKLAFILNVVIDKDKKIIASFAGDVEKAHTKGCRFVTELSKVNSIK
                     SDIVVTTNGGYPLDQNIYQSVKGMTAAEATCKDGGVIIMISACNDGHGGQSFYENVAN
                     ADSPKQLLDKIRSVDRVDTIPDQWEFQILARILSKYTVIMVTDKCNPEMIKKMHMKHA
                     FNFKEALEMANSIVGKESKVVVIPDGVSVIVK"
     gene            complement(73563..74276)
                     /locus_tag="KOU88_000229"
     CDS             complement(73563..74276)
                     /locus_tag="KOU88_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBK3210155.1"
                     /translation="MFNSIASKKVYEQVIEQIQYKILNGELKKGDKLLSERELSEQMN
                     VSRTSIREAIRVLETMGVIESRQGEGNFICTNIEKTLIEPLSMIFKLNNGTLEDILEL
                     RIILEIEIAKLASKRITSSEVIELKHIIDEMRVETNKKDNNRVLVLLDQKFHSKLATL
                     SKNYLIQSLFMTASKLFDGFIEDAREKIIAEPFNENILLKQHEAIYNAVVENDVELAC
                     EKAKEHMDFISKNYRKNEN"
     gene            74401..75660
                     /locus_tag="KOU88_000230"
     CDS             74401..75660
                     /locus_tag="KOU88_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YlbJ"
                     /protein_id="HBK3210156.1"
                     /translation="MKKNKIIAFFAPSIIVGVLVLGIILYPNEAIKSAREGFSIWSNV
                     LVPSLLPFIIGANLIVDLKIVDIIGFIINPITRFVFNVSGKSALAFAISTVSGYPVGV
                     SLASEFRSNGQISKYEAQRLVSFCSTSGPLFIIGSVGTGMFQNSNLGYLMILCHYLGT
                     ILVGLFFRNYGNENLPKTKLDLKTNIKNVINIRNSSGNGFFVLFGNAVFNGVNTLLTV
                     GGFVIVFSVVFKILSLFNVISLIASVIYLPLSFLGVSKELCQAFVSGLFEITIGCNKV
                     SSITSSPEILRASLASFLIGFSGLSILAQCCTFLSKTDIDLKLYILSKFAHGVLAAIF
                     IFILYPIANSAVLVSSFADTYNVIYNNLIWFYYLSYYDTILQIVVIIYLISAVFIAKK
                     HMKTLSTNGKLMRYKNTFFTKKFSRKK"
     gene            75940..76506
                     /locus_tag="KOU88_000231"
     CDS             75940..76506
                     /locus_tag="KOU88_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK3210157.1"
                     /translation="MATRPIEIDEYKKIMELLHTGFTYSENGVEKRFRKNPKVALALM
                     LEANLGLRISDILRLKIGNFKGNMLEINEKKTGKLQYRPVNKNIIESINEHARKYNLK
                     SNDYLVNIKTKAIQKQLRIICKHLNLYNISTHSFRKLYATTQFEKSNNNLELVKELLN
                     HSSVATTQRYIRVTQQAINEASENFFIG"
     gene            complement(76707..77912)
                     /locus_tag="KOU88_000232"
     CDS             complement(76707..77912)
                     /locus_tag="KOU88_000232"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBK3210158.1"
                     /translation="MKIAILGYGTVGSGLIDLIENNTSKRDIEVVGILVKNKEKHKYK
                     KYFDKITTDIEDIFDKDIDILVEVIGGLNPAFDYVTRALNKKIHVVTANKDLLAEKGS
                     DLIELANLNNVSIKFEASVAGGIPVLKPLIESLEGNNIKSINAILNGTCNFILSKMYD
                     ENLPYDVALKQAQELGFAEVNPDADVLGYDSARKLSILSTLSYGKIVYWKDLLLEGIT
                     SIDEKDIEYAKKLNCKIKLVARSKYESGEVSGFVRPALVDNNNMLSKIDNEFNVVILV
                     GDSVGELSFVGKGAGRGATGSAVYADIIDIIDNRSSNIKSFSKGKLDLSGLIEDECSA
                     VVRFGGYNNKDGILECLDKYVDSYDIIDDEELAIFVSAKSEHEIDRVLEIVKRNNYSE
                     SVKKLLKID"
     regulatory      complement(78015..78121)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(78213..78581)
                     /locus_tag="KOU88_000233"
     CDS             complement(78213..78581)
                     /locus_tag="KOU88_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbY family RNA-binding protein"
                     /protein_id="HBK3210159.1"
                     /translation="MLKGKQRAYLRSLANTLKPTTQIGKEGVTESFLEQLDGMLRTRE
                     LVKVTILENAGLDTKETANAVCEALRAEFVQAIGFKFTIYKRNIEEPKILFPGHEQAK
                     AKTKNNNVTKKGKPTKRAVR"
     gene            complement(78633..79910)
                     /gene="obgE"
                     /locus_tag="KOU88_000234"
     CDS             complement(78633..79910)
                     /gene="obgE"
                     /locus_tag="KOU88_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBK3210160.1"
                     /translation="MFIDKARIFVKAGNGGNGSVAFRREKYVPAGGPDGGDGGRGASI
                     IFEVDLGLRTLMDFKYQKKYQAQNGGDGSKGKRAGKNGENLVLKVPAGTVIRDEATGL
                     VLADLKKEGDTAIVAKGGIGGKGNQHFANAVRQAPAFAKSGTDGEERWITLELKMIAD
                     VGLLGFPNVGKSTFLSVVTKAKPKIANYHFTTLTPNLGVVQTKFGDSFVLADIPGIIE
                     GASEGIGLGHEFLRHVERTKVLIHIVDISGLEGRDPIEDFDKINDELKLYNEKLSKRP
                     QVVVANKFDILEDESKFEKFKSELEGRGYTVFKMSAATRQGIDEVIAYVSKMLKEVED
                     VELVSEEEMYRPELDIGTEEELSIDIEDGVYVVTGKALRRIMYSVNFDDMESLQYFQK
                     AMESQGVFDRLREMGIEDGDVVKIYELEFEFYN"
     gene            complement(80021..80311)
                     /gene="rpmA"
                     /locus_tag="KOU88_000235"
     CDS             complement(80021..80311)
                     /gene="rpmA"
                     /locus_tag="KOU88_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBK3210161.1"
                     /translation="MLNMNLQLLASKKGVGSSKNGRDSISKRLGVKRFDGQLVTAGSI
                     IVRQRGTKIHPGTNVGKGSDDTLFALVDGTVKFERKDKKRKKVSIYPVAIAE"
     gene            complement(80325..80642)
                     /locus_tag="KOU88_000236"
     CDS             complement(80325..80642)
                     /locus_tag="KOU88_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBK3210162.1"
                     /translation="MIKVKYYYNDDFLLQGFCLKGHADFAEIGYDIVCAAVTSNAIAV
                     INSLDKLQKIEFEKVVGEEGHIECIVKDTHVKDAQLLLNHFQLAVKEIKREYPKNIKI
                     LKK"
     gene            complement(80657..80968)
                     /gene="rplU"
                     /locus_tag="KOU88_000237"
     CDS             complement(80657..80968)
                     /gene="rplU"
                     /locus_tag="KOU88_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBK3210163.1"
                     /translation="MYAIVKTGGKQYKVSEGDVLFVEKLEANAGDVVTLNEVLACSKD
                     GELKLGSPVVEGASVQAKVVEQGKAKKVIVFKYKAKKDYRRKQGHRQSYTKIVVEKIN
                     A"
     gene            complement(81069..82490)
                     /locus_tag="KOU88_000238"
     CDS             complement(81069..82490)
                     /locus_tag="KOU88_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rne/Rng family ribonuclease"
                     /protein_id="HBK3210164.1"
                     /translation="MKKIVIESLIGSQKTAVLEDERLTELFVEDNLNKKTVSNIYRGI
                     VKKVIPGIEACFVDIGFKKLAYLQLKKGSTIKSGQDILVQINKEEIGTKGAKLNTEIS
                     ISGRYIVYIPSNDRTTISNKITDEKERFRLKKITKAVNKENLGLIIRTEAQGCTHDEI
                     KKDIEELKLKYENILKEYKLGIGPKLLYKSLDFATKYVKDNVNDDIESIITNSYDKYS
                     ELKSILRGIDKTYVDKLCLEENRDVFDLYRIESKIEKLLNKKVWLKSGGYLIIEKTEA
                     LTVIDVNTGKFIGTGKLDETVYKTNLEAAKEIVRQLRIRDIAGIIIIDFIDMHKKKHQ
                     KEILHILEEEFNKDKRKAEVLGMTKLGLVEVARRREKESIDKYYLMSCPCCDGEQTIK
                     SVHYILDSIEKEIMRISEHTVYKNIMVEFNDFIFEQIKEYYMDIIDKIGEKYNIKISL
                     NANSTLKHNKTNVIFDKIVDNKM"
     gene            complement(82508..83209)
                     /locus_tag="KOU88_000239"
     CDS             complement(82508..83209)
                     /locus_tag="KOU88_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2344 domain-containing protein"
                     /protein_id="HBK3210165.1"
                     /translation="MSKIIRVKFKKEGDMIYISHLDLQRLLQRAFRRAEINLSHSQGF
                     NPHPKMSYGNALALGTESQGEYVDIEIEEDDLSVEEFLNKVSIQLPDGIDFIKAKEID
                     RQTPSLSSVIDYGEYLFNIDLKRPMTKEFVKRKVIDFMNNKEIIITKKNKKGKMVEVD
                     IRPMIRTFDVLNLEDEHITLTATIATGSKTNLNTNILIPKILEMFELDIDPLDVDILR
                     RDLYVLEDGELVTPM"
     gene            complement(83211..85055)
                     /locus_tag="KOU88_000240"
     CDS             complement(83211..85055)
                     /locus_tag="KOU88_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03960 family B12-binding radical SAM
                     protein"
                     /protein_id="HBK3210166.1"
                     /translation="MNKVDLKKILKKVEKPARYLGNEINSIHKDTSNSELIRYAHCFP
                     DLYEVGMSHLGSHILYDVINKDEDVFCERVYSPAVDMENIMREKSIPLFALESREPIT
                     NFDFVTFTLQYELSYTNILNILDLANIPILKEERTLEDPFIMVGGPCAYNSEPLADFV
                     DVVILGEGEEVNLEVVNEYKEWKKNKTTREDFLYKISSIEGVYIPSFYDVKYNEDGTV
                     QSVTPNREGITKNPTKRIIKDVETVDYPEKLIVPYIDTVHDRIVLELFRGCTRGCRFC
                     QAGMIYRPIREKSVKRLKEILDKLVKNTGYDEISLSSLSTSDYSKLSELTDYLVDEYA
                     SNNIGISLPSLRLDNFSMEIADKIQQVRKSGLTFAPEAGTQRLRDVINKGVTEEDLEN
                     ATERAFEMGWNSVKLYFMIGLPTETYEDLDGIAKLAYKVIDIYRKVNGGKLKRSFSVT
                     VSTSTFVPKPFTPFQWHGQDTTEEVINKQRHLVNKLRNNNIKYNYHDSKTSLMEAVVA
                     RGDRRIGKVIYDAFRLGAKFDGWAEHFNLDIWKEAMEKNNLSIDFYAHRNRNYEEVFP
                     WDHIDVGISKKFLIREDENAKKEKITSDCRHNCNGCGINIHDIGRGLC"
     gene            85374..86567
                     /locus_tag="KOU88_000241"
     CDS             85374..86567
                     /locus_tag="KOU88_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FprA family A-type flavoprotein"
                     /protein_id="HBK3210167.1"
                     /translation="MSKVFEVKKDIYFTGVVDEGLKVFDIIMETEFGTTYNSYLIKDE
                     KTVLFDTVKANFKDEFLSNLSEVTDIAKIDYVVIHHTEPDHAGSLKYLLDINPNIEVY
                     CTKAAKLYLDGQINRPFNCHVIKDGEILNIGKRNLRFITAPFLHWVDTMFTYIEEDKT
                     LLTCDAFGCHFASVDAEVVNSEDYLKSAKHYYDCIVKPFAKHVLSAVDKVVGLNIEFD
                     TILTSHGPMLTKDPMAAVKRYVEWSTEAVNTTNQNQVSIFYLSAYSNTLEMAKKIKEG
                     LDKEGAKAELYDLEDMTLTEMHDTLVVSKVILLGSPTINKTMVKPMWDLFSVIDPMAN
                     QGKIAGVFGSFGWSGEGITMAETLLKSMSFKMPVESLKKKFFPSEETLKECMAFGAEF
                     AKLVK"
     gene            complement(86779..87861)
                     /locus_tag="KOU88_000242"
     CDS             complement(86779..87861)
                     /locus_tag="KOU88_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBK3210168.1"
                     /translation="MKKIRKLATKLLIATMVLTSCMSVTVYGMTAKDVTAKTPKSYVA
                     GTNSIYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKIRVAYNHIKNNTTYVNWNA
                     AEGANTAYTLVTKKGACSGMCRSLKALCDAMGIECYYVHSTTNDHQWNLIRFEDGRLY
                     HVDIDANKSAGADIIYKSLTHPLPFDKKAYPAVGEVVKTQNPTPTVKKPTPAKPSAPV
                     GPGNHTMIADQQGAILDEVYGNNLRPKIEMYEGVPCSLINSSINTIKFTSKNSNLDPS
                     KHTVTVIGFMNTPYGMVALAPDGVPDEYPFEYDKPFSLDFTGKNLSAAELSKKCKENN
                     VIIKVEIGETASNSGRGMVAYARYVN"
     gene            complement(88425..89216)
                     /locus_tag="KOU88_000243"
     CDS             complement(88425..89216)
                     /locus_tag="KOU88_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210169.1"
                     /translation="MKLIDEYLDKLYKKCDNKSTIELKQEMRCHLIESANEFKLEGLD
                     EEEACKKAIERFDDGDEMQYELCNIIKELSLSLDRHKSIVMGFKKVLGYISIIAFLIS
                     GFMWYYNNSLQHNMYNLGKELDGEIKQLAERHDMTKIGEYKLELEKILDKDKYSKVKA
                     LRLYVIDMKDGNTNLSSSGLNANMVYEREADYNNISNFIQHLGYNGKDFLDKNGNIVN
                     PDIFLEYFFYFESEMLIPVAFAFGLLCIIAYFILRFKISLIKNNN"
     gene            complement(89220..89549)
                     /locus_tag="KOU88_000244"
     CDS             complement(89220..89549)
                     /locus_tag="KOU88_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210170.1"
                     /translation="MQLNKEVLKGYIDILIVSILEKKDCYGYEIAKQVRERSEFELKE
                     GTMYLALKRMESKNLIKSYYSNEQSSGGRRKYYNLTNEGKDFLEIKKQEWRFIKKVMN
                     QFLGEVD"
     gene            complement(90034..90447)
                     /locus_tag="KOU88_000245"
     CDS             complement(90034..90447)
                     /locus_tag="KOU88_000245"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBK3210171.1"
                     /translation="MNIALVAHDQMKNTMVGFCIGYESILKKYGLYATGTTGKRIMDE
                     TELNINRLASGPLGGDQQIGSLIVTQEIDLVIFLRDPLTSQAHETDIQALIRLCDVYH
                     VPIATNLASAEIFIKALDRGELSWREVRKSKSQRI"
     gene            complement(90488..91618)
                     /gene="rodA"
                     /locus_tag="KOU88_000246"
     CDS             complement(90488..91618)
                     /gene="rodA"
                     /locus_tag="KOU88_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HBK3210172.1"
                     /translation="MKKININYKSTIKLIKQLDWKLIVTVLAIFIFGLVILSSATHAN
                     STGSYNQLIKQGLAFVLGIGMIIVILFFDYNLLGRYYKALYIISLILLAIVLLPGIGT
                     VKGGARSWINLGPLDLQTSEIVKLTFVLSYAKILESKKDKLNTLKEVMPVVVYSLPFI
                     GLLIAQPDLGTGIVFCCMIFAMLFTAGLSSKLIKRGIIILLVSMPLMYLMMADHQKVR
                     IEAFLNPEDVTLKGNYQVMQSLIAIGSGGVTGKGLYNGSQNQEDFLPVQDSDFIFAVV
                     GEELGVIGMAVLIILFMIFLLRLLAIARDAKDFYGTLIVVGVMGMFGYQIIQNIGMTV
                     ALIPVTGVTLPFVSYGGSSLLTSLANLGLVLNVCMRRKKINF"
     gene            complement(91703..91987)
                     /gene="minE"
                     /locus_tag="KOU88_000247"
     CDS             complement(91703..91987)
                     /gene="minE"
                     /locus_tag="KOU88_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBK3210173.1"
                     /translation="MLDLFRVFSNEAKTSKSVAKERLKLVLVHDRVDCSPQLLEMIKT
                     DILKVIANYAEIEDDGLEIKMSKCRGEHDDKPVSALVANIPLKNIKDRCM"
     gene            complement(92005..92802)
                     /gene="minD"
                     /locus_tag="KOU88_000248"
     CDS             complement(92005..92802)
                     /gene="minD"
                     /locus_tag="KOU88_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBK3210174.1"
                     /translation="MSEVIVITSGKGGVGKTTTAANLGTALSLENKKTVVVDADIGLR
                     NLDVVMGLENRIVYDIVDVVEGTCRLKQALIKDKRFDNLYLLPAAQTRDKNAVSVEQM
                     IDLCEKLKESFEYIIIDCPAGIEQGFKNAVAGADRAIVVTNPEISAVRDADRIIGLLE
                     ANEIKEIRLVINRIRNDMVKRGDMMDKQDIIEILAIDLLGLVPDDESIIISTNKGEPA
                     ILDSKSLAGQAYKNIAKRILNEEVPLLDLEVEDGFFGRLKKMFSMAK"
     gene            complement(92826..93509)
                     /locus_tag="KOU88_000249"
     CDS             complement(92826..93509)
                     /locus_tag="KOU88_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBK3210175.1"
                     /translation="MSLREICSQELVEFKGNKRGIIVNIKREAPFEEIQEKIINKLEA
                     YVGFFNGAKISKINSDCLTDMEILELKEGITSRFDVEFVEDQKIEENSNFPTKYVNTL
                     RSGENIEFEGDVVILNDMKPGSKVLSKSNTVVMGDINAGAKVVAGGNVFVMGKIEGFV
                     HAGAEGNEFAYVVAGNLNPKILQIADNIAEAPDDEENYESESEISPEIAFVSNGRIVI
                     ESYLSKLDK"
     gene            complement(93607..96585)
                     /locus_tag="KOU88_000250"
     CDS             complement(93607..96585)
                     /locus_tag="KOU88_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBK3210176.1"
                     /translation="MEENKQVDRLKIIKIVMGVIFLAILVKIIYMTTFKYEYYNELAE
                     NKTYKKLAIEAPRGEIKDRYGRLLAGNKNLFTVQVSGNDINKKDANKHSRANEISLKL
                     INLLERNGEEYVDEFPIYVENGKYYYTYDRDIREYKSENGIPNDYNAKESFYYLVDKL
                     ISAGILSQEDKRLDATRLQAKLNENGYYPPILVSKWMFTAERDKRDWLASYKIKETKL
                     SAKEAFEKVRNSDALEIDKSLSDEDARKIMVVRDLIKSKGYSQYNPVTIAKDVGETTI
                     AQIEESAMDLVGVSIAVEPVRYYPNGSLASHMLGYVGKMPSTQIESYLQKGYETGDMV
                     GLAGVEKSNESRLRGTDGYKMVKVDALGRISKEIESKKPKSGDTVYLTLDKDLQEVSD
                     NALKQIIEVASKGGTFKSKFGDKPISAYAGKAQSAALIAIDVKNGEVLASSSYPNYDP
                     NKFAKGISTEDYKALQPKNPNDLLAGSPLLNLVTQGEFQPGSSFKMVTSMAALENGLD
                     PNFTINDPGVIMLGKKSFGDYVWNHGRGNHGMTNLYKAIQESCNIYMATIGTGKTWPD
                     GKSIGIDMNANKILEYAKLFGLDQNTGLQDEVEERAGKVPSTEDKLKSTQALLKSNLE
                     REMANDFVDITREKNPKEYEKRINEIVSWAAEKKTPGRVETMNRLKKLDVKEDRIEEV
                     ADLAVFSYFNFAKWSTADTFNLAIGQGENAYTPAQISRYVAAIANGGNLVELSVVDRA
                     VSSDYSSVKINDQKKVEKIPFKNPDNLKELTKGMKLVARQGTAKSAFADFPIDVAAKT
                     GTAEKSGKIPTDNEYEYLKSHMSSYNVNLNDAIKLADKMKAEKEKELSLAKEKEIKKK
                     LENKDLKDEERKKLEEELEDGVKVRLEDTDKVNSSYLRKAIKELNPKITDDQIDRFKQ
                     DYGSFTWTVAFAPADDPEIAVVCVIPQGDSSVFSLLPTREVIGTYMGLEPTNSKNDNK
                     TNDVNNSSDENINFESQINR"
     gene            complement(96597..97085)
                     /gene="mreD"
                     /locus_tag="KOU88_000251"
     CDS             complement(96597..97085)
                     /gene="mreD"
                     /locus_tag="KOU88_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBK3210177.1"
                     /translation="MKKVLLCLLGIVLMTIENSITNYIDIFGISFNLVLIYVTIISLY
                     LDELEGGIIAAIIGLIKDITVGGIFGVNALILFIIAYAIGYMRDQLYKGSYIITFVLI
                     FIGSLIDSIVNIGTSSIIYQSYNISTLFVKGLLVAPIVNSLIGLVIYRLSKRAVLKLK
                     ED"
     gene            complement(97100..97993)
                     /gene="mreC"
                     /locus_tag="KOU88_000252"
     CDS             complement(97100..97993)
                     /gene="mreC"
                     /locus_tag="KOU88_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBK3210178.1"
                     /translation="MALRFDKNKNEKKRINVKVIATGVVAITLIGIVGISIGKFSSGS
                     PVNLGVASDAITSVGKGINDGFSFIKNGFKDVANFKDNSKKVKKLEEENEKLKKNMIA
                     LNAKLDKTESLEELKKTLNFVQEEYKATSISASVVGKNDGNWYESFVIGAGKNSGVKK
                     ESIVMNGSGLVGIVYEVSNNYSKAISLLDSKASVSFKLAKDANAKGTITQNTTLDNKD
                     SYNSKGYLQGYMFDSSYNVIQGDIITTSGLGFFPDGIPIGEVEKVVDDKDKSLKYVVV
                     KPYVDFKNINDVVVIEPRNIG"
     gene            complement(98003..99013)
                     /locus_tag="KOU88_000253"
     CDS             complement(98003..99013)
                     /locus_tag="KOU88_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBK3210179.1"
                     /translation="MTKDMGIDLGTANTLVYIKGQGIVVREPSVVAIRDDSKEVLAVG
                     EEAKKMIGRTPGNIVAIRPMKDGVIADFDITQSMISYFIQKAADKKGVVSPRIAICVP
                     FGVTEVEKRAIEEAARQAGAKDAFLIEEPMAAAIGAGLKVEEPEGNMVVDIGGGTSEI
                     AVISLGGIVTAKSIRIGGDEFDESIVAYVKKEYNLMIGERTAENVKINIGSTFKDDEE
                     INMQIRGRDLISGLPKTIEICSTEVREALKEPVSSIVDAIKSTLERTPPELASDIMEN
                     GIMLTGGGALLRGLDKLITQETGMSVQIAETPLDCVALGTGKSVEDQEIFEKVLMMNT
                     KN"
     gene            complement(99134..99793)
                     /gene="radC"
                     /locus_tag="KOU88_000254"
     CDS             complement(99134..99793)
                     /gene="radC"
                     /locus_tag="KOU88_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBK3210180.1"
                     /translation="MAPEERPREKMLAKGVKSLSNAELLAILLRTGNKNKNAIELANY
                     IINRDIQGIRHLEDMTIEELCNIDGIGLSKSTQIKAALELGSRVASFKPIKYKIRNPW
                     DIQRYYMDSLRYLKKEVFKAVLLNTKNEIISDVDVSIGTLSSSLVHPREVFKEAIRRS
                     ASKIIVMHNHPSGSVEPSREDKNITSRLIKCGEIIGIEIIDHIIIGDGLYFSFKENMI
                     I"
     gene            complement(99838..100422)
                     /gene="maf"
                     /locus_tag="KOU88_000255"
     CDS             complement(99838..100422)
                     /gene="maf"
                     /locus_tag="KOU88_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBK3210181.1"
                     /translation="MNIILASASPRRKEILENTNVRFDIIKNEIDEIILEGETPKHLV
                     MRLAFEKSMSVASEHNEDVVIGADTVVVLDNAILGKPKDESCARDMLKRLSGREHQVI
                     TGISLINLCEDKKVIDYVISNVKFKTLSEQDIEDYLKTNESFDKAGAYGIQGYGALLV
                     EEIRGDYFNIVGLPISRLGDLLKKYFSINLFYGV"
     gene            complement(100642..101613)
                     /locus_tag="KOU88_000256"
     CDS             complement(100642..101613)
                     /locus_tag="KOU88_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit B"
                     /protein_id="HBK3210182.1"
                     /translation="MVILTAVLVLGIMGLIFGIVLDFASKKFAVEVDERVEAILGVLP
                     GANCGGCGFPGCGGLANAIVEGNAPVNGCPVGGADVGAKVGEIMGISAEAGEKQVAKV
                     ICKGTCSSAKDKYEYEGISDCRAANVLNSGAKMCKFGCLGLGTCKDACKFDAISIVDG
                     IAVIDEEKCVNCGKCKEVCPKGIIITKPESQEVVVECNSKEFGKAVKEKCTAGCIGCG
                     MCVKACKFDAIIFEDKIAKIDPNKCVGCMQCVAKCPTKVISGDITKKKKVTIDQELCV
                     GCTVCKKQCKFDAIEGELKEKHKVDADKCVGCHLCMEKCPKKAIKIL"
     gene            complement(101629..102204)
                     /gene="rsxA"
                     /locus_tag="KOU88_000257"
     CDS             complement(101629..102204)
                     /gene="rsxA"
                     /locus_tag="KOU88_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBK3210183.1"
                     /translation="MNLILLFLSIVLVNNVITSQFLGICPFLGVSKKVDTAVGMGVAV
                     TFVLTLASIITYFIQILLVKTGTGFLQTIAFILVIASIVQFVEMVIQKMSPSLYQALG
                     VYLPLITTNCAVLGIALVNVQKSYNLVETIINGFGAGAGFTLAIVIFAGIRERLELAD
                     IPEAFKGFPITLISAGLMSIAFLGFTGLIKL"
     gene            complement(102219..102812)
                     /locus_tag="KOU88_000258"
     CDS             complement(102219..102812)
                     /locus_tag="KOU88_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit E"
                     /protein_id="HBK3210184.1"
                     /translation="MNLAKVFKNGLIDENPTFVQVIGMCPTLAVTTSAINGIGMGLST
                     AAVLICANLVISLIRKITPDKIRIPIFIVVIATFVTIVGMLLKAYVPALDKALGIYIP
                     LIVVNCLILARAESFAFKTGAMPSIVDGVGQGLGFTVALTIIGAVRELLGNGSLFGMT
                     LFGASFQPVLIFILPPGAFLTLGFLFAGFNKLRSKKA"
     gene            complement(102825..103394)
                     /locus_tag="KOU88_000259"
     CDS             complement(102825..103394)
                     /locus_tag="KOU88_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit G"
                     /protein_id="HBK3210185.1"
                     /translation="MNSMVRLGGTLLAISAIAALALGATNQVTAPVIEQRNIQANNEL
                     RKAVLPEAKEFKEMKEDTYKGLGDDLIAEVYEGLDGSEVVGYTLKAKPSGYGGEIEVM
                     VGISSEGQVTGVDIGNMSETAGLGAKAKDDAFKGQYKGKTAEPLEVAKGSTTADNQIL
                     AISGATITSTAVTTGVNAAIDVFNSALNK"
     gene            complement(103394..104371)
                     /locus_tag="KOU88_000260"
     CDS             complement(103394..104371)
                     /locus_tag="KOU88_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfABCDGE type electron transport complex
                     subunit D"
                     /protein_id="HBK3210186.1"
                     /translation="MENKLIVSSSPHVRSNEDTSYIMKQVIIALLPAAVAGVYFFRLN
                     ALSAMFFCILGTVGTEFLYQKFTKQKSTIGDFSAVVTGLLLAFNVPASLPWWMCLVGG
                     IFAILVVKMVFGGIGCNFVNPALAARAFLLASFPVAMTAWTQPGVNWIGKNLDAVTTA
                     TPLSFLKNGAAGLADLSSNGISLADMMIGNIGGCIGETSAILLLLGGVYLMYKGIINY
                     VIPVFYIATVFILTFLLGGFNITFAIYQLFAGGLMLGGFFMLTDYTTSPMTKKGQIIY
                     AVLAGLITTVIRMYGGYPEGVSYSILLVNCLAPLIDKFVRNRVFGEVAK"
     gene            complement(104394..105731)
                     /gene="rsxC"
                     /locus_tag="KOU88_000261"
     CDS             complement(104394..105731)
                     /gene="rsxC"
                     /locus_tag="KOU88_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBK3210187.1"
                     /translation="MKLLTFKGGIHPPYRKEYSNTKALEKAQAPKIVYIPLQQHIGAP
                     AKPIVEVGDEVKFGQKIGEQQGFVSCNVHSSVSGKVIAIEQHEVPGGSAQCVVIENDF
                     KEELHESVQPKGQLEDLSKEDIVGIIKEAGIVGMGGATFPNHVKVSPPPDSKAEVVIL
                     NGAECEPYLTADHRLMVENPEDVVFGLRALMKVLDVKKGFIGIETNKPDAIEAIQNVA
                     KDYSEIEVVGLQVKYPQGAEKQLIYACTGKEVPSGGLPIAAGAVVDNVATAAQIAKSI
                     KTGMPLVERITTITGSCIKEPKNLITKVGTLVSEIIEQCGGFKEDKKIGKVIMGGPMM
                     GIAQYTTEIATNKGSSGILCLDEEESRTPDIQNCLRCGRCTDVCPSFLQPLFISAYSL
                     KDDYDTAEYHRAMDCIECGSCSFICPARRPLLQSIRSAKREIGAKRRKQAAQK"
     gene            complement(105947..106891)
                     /locus_tag="KOU88_000262"
     CDS             complement(105947..106891)
                     /locus_tag="KOU88_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210188.1"
                     /translation="MNRRKTIYRGFNNNRHKIDLRKYVITIACLCLIGYYSYTKIKDS
                     KILEYVSAKIPFLNNSSDITYKDISDELNSIKKGKKSKSQTNSDDKQETNPEKAVNNT
                     KEPEEVKLATIEGWDMYTIQVAAIDNNDDLKKIQTSLVNNDIPFSVMEKDGVKKIQTY
                     SSFDENDVRKQISSVRKVFPDAFLSHLDAPMLSLEYTSNYAYIESISKELNKLITNFK
                     EESSFWSNAENNVDMEKYNTILTNRKAISQNISKEAEKIDYSEMRLFKDNLIEYVKNV
                     NEKIDTASKAANEEKYSVSKSLLLSSMQEYSMFINSIK"
     gene            complement(107002..108276)
                     /locus_tag="KOU88_000263"
     CDS             complement(107002..108276)
                     /locus_tag="KOU88_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBK3210189.1"
                     /translation="MKKAIAALGIGAVAVSVSSINASALEKGTVTASALNIRSGPSSD
                     CDKVAKLYKGKTVEILEKSNGWYKVRVSSSVVGWGSAKYISTSGSSEGTSSQNNPTSS
                     GTTISGNGKVNVSSRLNVRSGAGTNYSLVGKANNGDVVKLLEQSNGWYKIKLSNGVTG
                     WASSQYISKTSEDVGTNNSSNSNSTNNSDKKPSSEESIEGKNGKVTSAVSLNVRSGPG
                     TSYSIIGKLNGGDVVELKAKSNGWYKVKLSSGTIGWVSASYISETNEGTKEKPNSSSN
                     QNSQPNSNSKPSFTGNSDKSTAKGSTIVDFAYTLIGIPYQWGASGPDKFDCSGFTQYV
                     FKHSVGVSIPRVSREQANFGSAISMGNYAPGDLVYFDTDGDGTTNHVGIYVGNSKFIH
                     CSGTQTNPNKVKVDNLTSSYWSKVLLGARRFV"
     gene            complement(108408..108779)
                     /locus_tag="KOU88_000264"
     CDS             complement(108408..108779)
                     /locus_tag="KOU88_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK3210190.1"
                     /translation="MKFNFCHNNFNVTNLEKSLDFYKKALGLKEVKRKEAEDGSFILV
                     YLGDGITSHTLELTWLRDWDRPYNLGDNEFHLALEVEEFDEAKKLHKDLDCICFENES
                     MGIYFIADPDNYWIEILPKNH"
     gene            complement(109007..109606)
                     /locus_tag="KOU88_000265"
     CDS             complement(109007..109606)
                     /locus_tag="KOU88_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210191.1"
                     /translation="MESRGYKEDLKKMILDMAHKELESYVSQKGAKKYFEGNLDKIIN
                     NNIKKFNQSIGLNRVYLKMLKKCAYQESVTSISRTIKKEALFKSKKELFAFSEYLKLD
                     INKRLSYNQILRKISRYIYYNRSSYAQKYVVFKRGDEEYLLEPEKIKDELISSYRSKT
                     REDMRSIAKLLDIEVEDDYNAEDIRKKVINYIIKEKLKS"
     gene            complement(109807..110019)
                     /locus_tag="KOU88_000266"
     CDS             complement(109807..110019)
                     /locus_tag="KOU88_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HBK3210192.1"
                     /translation="MKKKLLVEGMSCGHCVNHLKTALTEDIDGIEVLDVDLENKCASV
                     DMKDDVSIEKLKEVIAELGFELKGIE"
     gene            complement(110092..111807)
                     /locus_tag="KOU88_000267"
     CDS             complement(110092..111807)
                     /locus_tag="KOU88_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3210193.1"
                     /translation="MKRIKVLTVVLAITLMVAGCSNTKTKQSSSDSSLQSQSSIDAKY
                     INLTMVTPKTINPITNTDKSVGYIMNLVYDSLFTIDENYNVIPQLVKEYNIAQDGMSI
                     DIKLKDAKWHDGKNVTSNDVNYTIGLIQKSADSPYNEFTKNIASVNIKSDKDFTIKFK
                     ARYAFSIDSLIFPIVSQNHLDSKDVNDKNNNMIGNGKYKIESYTEREGMVLSVNKDYY
                     EEVPKTMKNIKVGMVPNEDARTSMVMALDSDITNVTLNDLSKFQEKEFNITKYQGRDY
                     ECVLFNYNNPFFKDVNFRKAIAHSIDKDRIISEGYMDDATPVNFPLNSKSKYYNSEMK
                     DLEFNKDKAIECLAKVEYANVNSVNQNDNKVKNQKKSAKKNSKKLTPEEEAKAKKAEE
                     DRIKKEAEEKKNREKEEVKKSLSEMNLKIIVNRDNSERIKTANIINENLKAIGINSTV
                     NQLSDKDMENALNSKNYDLALVGWKLSIIPDASSIIASSGYTDDKLNGYMSALTSSTS
                     EIETKKAYKDVQTYIKDNATFISLAVRNNYIVSNSRLKGKITPNDFDVYEGISNLDIK
                     SNESN"
     gene            complement(111807..112361)
                     /locus_tag="KOU88_000268"
     CDS             complement(111807..112361)
                     /locus_tag="KOU88_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBK3210194.1"
                     /translation="MNSKKVLILSIFIILFGALLMESKVIHKFLYPKKYSEYVEKYSK
                     EFNLDENIVYSVIKAESKFNSSAVSKKEAKGLMQILDITRDWGAEELNLKNVDIFDPE
                     TNIRLGCWYLSKLYKEFGKLDLVIAAYNGGSGNVKKWLENNEYSKDGENLHDIPFKQT
                     SKYVEKVKNNYEHYNKIYGKKGKN"
     gene            complement(112354..112956)
                     /locus_tag="KOU88_000269"
     CDS             complement(112354..112956)
                     /locus_tag="KOU88_000269"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBK3210195.1"
                     /translation="MLILGLTGGIGCGKSSLSNIFRNLNIPIVDADIISRKIFEDKLL
                     LEKVFVHFGQSIKNDDGTLNRKALGKIVFSDEEKLKELNNLTHPRIREKIISEIEKLR
                     KKGENIVVLDAAILVESGFLDMVDKLLVVTCKQEVQISRIQKRDNCSEQEALSRINSQ
                     MSQEEKSKYGDYIIDNSGTITELESKAHKFIEYMKENWRE"
     gene            complement(112965..115613)
                     /gene="polA"
                     /locus_tag="KOU88_000270"
     CDS             complement(112965..115613)
                     /gene="polA"
                     /locus_tag="KOU88_000270"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBK3210196.1"
                     /translation="MEKKLIIIDGNSIINRAFYALPEMNNKEGLKTNAIYGFTTMLFK
                     MIDIYKPTHISVAFDRKAPTFRHLEYKEYKAGRKGMPDELAEQLQPLKDLLDKFKINR
                     LEIDGYEADDIIGTVSKKAEENGYKVYIVTGDKDAIQLASDNTTTLITKKGVGEVEEY
                     NFNSVIEKYEMTPTQFIDLKGLMGDKSDNIPGVPGIGEKTGIKLIKEFSSIENLIENT
                     DKLKGSVKKKIEENKEIAIQSKRLATIIRDVPIEVDLDSMIFGDYDKDELLDKFRYFG
                     FTSLLSRLVDLVDSDDTEHVEEKIEILKLKDIEKFIDEVNKKGQVILKTVRGQGNILE
                     KNIIYIFISVDGEKIYYVDSNEVSKLDSIFSNNEIKKYGYNLKDDYISLKPYNINLEN
                     MYFDITIAEYLIDSTSSTSYDCSAIAMKYLSKKVKSKEELLGKGVKSKNYEDLEFEDL
                     AEYMGQIICTVKETVPMMERSLMDMSMDGLFYHVEMPLVEVLGHMEYEGIKVDKSILD
                     ELSVEFKEIIATLEKEIYELSGEPFNINSPKQLGVILFEKLELPIIKKTKTGYSTNAD
                     VLEKLRDKHPIIDKITEYRQIVKLNSTYVEGLLNIINPESNRIHSSFNQTITTTGRIS
                     STEPNLQNIPIKMEMGRKIRKVFIADDNCKLVDADYSQVELRVLAHMSQDENMIEAFK
                     HHEDIHTKTASQVFNVPMEDVTSELRGAAKAVNFGIIYGKSDFGLADDLNIPVPKAKE
                     YIESYFAKYHKIKEFMDTTVEKASEDGYAVTILNRRRYIPEIKSSNFMERNRGKRFAM
                     NAPIQGSAADIIKIAMINVHKKLEENNLKSKLILQVHDELIVEAIDDEIDIVKKIVKE
                     EMENAVNMDVHLDVDLNVGSSWYETK"
     gene            115765..115852
                     /locus_tag="KOU88_000271"
     tRNA            115765..115852
                     /locus_tag="KOU88_000271"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:115799..115801,aa:Leu,seq:caa)
     gene            complement(116039..116482)
                     /locus_tag="KOU88_000272"
     CDS             complement(116039..116482)
                     /locus_tag="KOU88_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210197.1"
                     /translation="MKKNMLYVGIIYFICGILLVLLATFTEFSFEAFIWGLSGAALGP
                     GVCMILQYMYWSKPERAVDYEEKIKNQRIEMNDERRIMLRDKAGRITNQIMSYVLVIL
                     IFIVSILSVFSVMVISKWVLVVLGLLILFQFICSVVVYNKLDKKL"
     gene            complement(116485..116682)
                     /locus_tag="KOU88_000273"
     CDS             complement(116485..116682)
                     /locus_tag="KOU88_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004631111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210198.1"
                     /translation="MKNRLEEIRKERGIKQEELASILQVSRQTIGSLENGRYNPSIIL
                     AFKIARYFDMSIEEIFIYEEE"
     gene            complement(116874..117740)
                     /locus_tag="KOU88_000274"
     CDS             complement(116874..117740)
                     /locus_tag="KOU88_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK3210199.1"
                     /translation="MEWINKLNQAITYIEENLESGVDYAEAAKIACCSTFHFQRMFSY
                     IAEVPLSEYIRRRRMTKAAFELQNSNIKILELSEKYGYDSPTSFNRAFQNIHNISPSA
                     ARAKGVVLKAYPKMTLSIYVKGNIEMQYRIVEKKGFRIVGIKESMNMIVEECFEKVPK
                     LWAKCIKNGTIDKLSELINNEPCGLLGVSVCTNSKGLDYYIAAPTDKPVLEDTHEYLI
                     PSGTWAVFECVSPMPNALAIQELQKRIITEWLPSSGYVYANLPDIELYPNGDINAPDY
                     TTEVWIPIQKPS"
     gene            complement(117966..118835)
                     /locus_tag="KOU88_000275"
     CDS             complement(117966..118835)
                     /locus_tag="KOU88_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK3210200.1"
                     /translation="MDYKTIILNRKSVREYKNTDIKEEYLSEIKKYSESCKKLVPEID
                     VDVRIMNRSEVFNNLDKVAGYKGNMIDSPSYIIILSDIKDNYIENSGYIGESIIFKVT
                     ELGIGSCWVTFEDGKKVKEKLGINSDKEVTGIIAIGYGENVSNAKVLNATKTGQNYSK
                     SDMQVVTDKGSTRLGVEDVVYMNEWGNVASIEILEERALLDAFHYARLAPSTLNRQPW
                     RFIVDGGTVVLAVRKDGHTNLYEEKIDIGIVMLYFATIISATMFDLKWNLGTPDKDYK
                     VPEDYKIVGYCNI"
     gene            complement(119341..119562)
                     /locus_tag="KOU88_000276"
     CDS             complement(119341..119562)
                     /locus_tag="KOU88_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210201.1"
                     /translation="MNVNNHKCPECGEHSKKFEIVEENEDCVIFECYTCGTISILKYC
                     ENCKEFVFVNIPNNVETYEYCCGKCNNKI"
     gene            complement(120063..121043)
                     /locus_tag="KOU88_000277"
     CDS             complement(120063..121043)
                     /locus_tag="KOU88_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210202.1"
                     /translation="MGDTSRFYESVKNKYPKLKDGTRVHLWPKENIIIGPIYDEEDGY
                     KKSIGNVDSLSWKQIVILAECDGKNTTDDIINILSNRYRNIHNMKEKVMEFFMFYENV
                     YLTFEDDIQTLSSVFEITGNKSYITPLYFTIEIDGDNNTNDYFSEITSLLNCMYEKGC
                     RFIEVIGEDILKNKSMREIFQYMLDHFDLIVVTKDSFTIDRSLIKELDNYRHKVIWKV
                     YSKNDDTRIKLKEDIKITSLIKRGHTVVRGDREKAIKIEDMRFKDTKERFSKYGAEWS
                     HLYISSDGSVKSYSFQKDKRIYLGNIFNNSVEEIFLEMQNKIDKLEIVYQ"
     gene            complement(121207..122079)
                     /locus_tag="KOU88_000278"
     CDS             complement(121207..122079)
                     /locus_tag="KOU88_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK3210203.1"
                     /translation="MIIKVSMTVLVLILLYILYKYETQHIETTEYTIFNKKIPKEFDN
                     FKIVQVSDLHNKVFDKNNKVLIDKIESLNPDVIFITGDLVDGENKNFQVALDLIDNLV
                     EKYEVYHIIGNHEQKSLIKKYKHLYKDYFKELYSKKIINMENESVRIYRGNSHLNLYG
                     LIIPLECYPYLFANNKKLELSDNFVEDNLGKVNENEYNILLAHTPFFFEKYAKWGADL
                     VLAGHVHGGIIRIPFVGGVLSPNREFFPKYDWGKYEKDNSTMILNKGLGGSKVLIRLN
                     CKPEIVKITLKYEK"
     gene            complement(122243..122794)
                     /locus_tag="KOU88_000279"
     CDS             complement(122243..122794)
                     /locus_tag="KOU88_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3210204.1"
                     /translation="MDNKFPNVGENLRLLRQEMGISLDKASKMTGVSKAMLGQIERGE
                     SSPTVSTLWKISSGFKINFTTLLNENTNTYEVIKKEEVEPIVEQKGNMKLYPIYPFSP
                     QRRFELFIIELEENCTHVSSTHSHVLEEYVLVIEGKLDLNVDGKTYILESGHSIRFDG
                     TLEHIYKNLNKGKTIFHNIEVYR"
     gene            complement(122814..123716)
                     /locus_tag="KOU88_000280"
     CDS             complement(122814..123716)
                     /locus_tag="KOU88_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBK3210205.1"
                     /translation="MSKKGRVVKVQHFSVNDGDGIRTTIFLEGCKLKCKWCSNPDSWS
                     NIVKLGVMKDKCVSCNRCIDVCPQNISSLFDRTQINNKCDLCGECIKVCLKDAICIMT
                     EEMSVEEIVEEVEKDFIFFFESNGGITFSGGEPTLQIDFLRELVDIFYDKGINIAIET
                     CGYFDWNKVNDVFEKIDHIFVDIKSMDDNIHKEYTGVSNKIILDNICRLSKLNKSMVI
                     RVPIIYGVNDSEENIRNTALFVKQNVPGGKMELLPYHKFGIDKYKALGLEDYIYEFDE
                     ICNNHMLKLKEIVELTGVKIIEYK"
     gene            complement(123731..126103)
                     /locus_tag="KOU88_000281"
     CDS             complement(123731..126103)
                     /locus_tag="KOU88_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase/glycerol dehydratase
                     family glycyl radical enzyme"
                     /protein_id="HBK3210206.1"
                     /translation="MSQTNRIEAFRQEYINSKPMICCERARIFTESHKKTEGEAICIR
                     RAKAFLETCKELPIKIFENELIVGTAGKFRRTGILTPEFSWQWVDKEMDTFDKRTQDP
                     YVISKEQIEFIRKEIFPYWKGKSLEEVFLARIPEDTAKILVDTGIIDNDSKWRQAVGE
                     VTPDYQDILFVKGYKGIKEDADKKIKELDISVSENIEKIDFYKSVSIVAQGIMTLAQR
                     YSNLAKEMSKQETDEKRKLELIKISEICMNVPANPPTNFYEAIQFVWFVQLGGILSEN
                     PLALNLGRFDQYMYPYYENDAREGKITESEAQELIEALWIKLSEWVWTISANTANYFA
                     GYNQFQNLTVGGKKRNGTDGTNDISYMCLKATESVKTHQPGLSVRVSQGAPDNFVMAV
                     AKLVKQGTGFPAIHSDSAGAQMLLQDGYDAEDARDWSNCGCVVPHFRKTGQWTSAVNI
                     NFAAALEYAMNEGKSRLTGEKMGLDTKNITEFTSFEELKDEFLKQLAYLVKSSVIGTT
                     VAQQIHKEMVPRPFLSTCVDGCLDKGVDLSKGGAKYNIGPVLTGIGLGVVSNSLAAIK
                     KLVFEDKVTTLEELTKALNNDWEGYEELRKLALDVPKYGNDNDYVDSLAIEVSDFYYT
                     ETRKYKDIFGSKFNSAFMGISNYVPTGKIVGATPCGRKATKPLTEGVSPFVGTDTTSP
                     LAAMKSASKINHDVHTGGTLLNLRLNQDLVETERGLRNLTSMIKSYFALGGFHVQFNT
                     ISNDTLLKAQENPEEYKDLLVRVAGYSTQFVNLSREMQDAIIARNSHSNF"
     gene            complement(126324..126527)
                     /locus_tag="KOU88_000282"
                     /pseudo
     CDS             complement(126324..126527)
                     /locus_tag="KOU88_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(126698..127891)
                     /locus_tag="KOU88_000283"
     CDS             complement(126698..127891)
                     /locus_tag="KOU88_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK3210207.1"
                     /translation="MKEKRRDSKERILHTGESQRTDGKYLYKYVDAFGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRANVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDCVRKNPFNFKLSEIIENDTKEKVALTEEQEQALLSFIKTDNVYHKYYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVVIDHQLLKSKEQGYYIETPKTKSGTRQVPLSR
                     ETIQAFQRVIRKRTKGKLIEIDGYKDFLFVNPKGNPKVAIDYNALFVRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            complement(127970..128173)
                     /locus_tag="KOU88_000284"
     CDS             complement(127970..128173)
                     /locus_tag="KOU88_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBK3210208.1"
                     /translation="MNNNDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWLI
                     MNGNRIQIKRRQFEKVIDKLDAI"
     gene            complement(128173..129264)
                     /locus_tag="KOU88_000285"
     CDS             complement(128173..129264)
                     /locus_tag="KOU88_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018594174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK3210209.1"
                     /translation="MTTHKNLSVKIDYISIVFETATAEDVIMHILDLPTDIFNVYPAM
                     IKFKTYQARWQIGDIYVSGDARKTEDNPQGLGCYLVMTGRGCDDIFRILDSRNYTFGD
                     MFRRCERRYGLDNFHFTRLDIAIDDKNEKPFFTIEQIKKKCEKEEFISNSEGYHFDES
                     KFDDFDTAKTVYIGAGKSGLSYRFYDKDKEVCSKHNKTLDEVGSWKRTEMQLRDDKAH
                     VFAMTFKDRPLELGELAFGLLANNLRFVVPNRNESNKSRWKTCRFWERFLGAVEVLKL
                     QVPKLHNSLEETQQWLTEGGVISAVKSFYFLEEHDALGGLEKVGTMLDRARYSSSLSS
                     KLTAHLQRIDRTDLIPYIQYDTKHGKGGI"
     gene            129721..130356
                     /locus_tag="KOU88_000286"
     CDS             129721..130356
                     /locus_tag="KOU88_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210210.1"
                     /translation="MEHYEKKISFLGENIQTIRKHRGMKQQELADKIGINMQSLSKIE
                     RGVNYPTFDTLEKIMDVLGVTPNELLSGEWKFVSQGEKEVCQFLRTEERLKAELKHGH
                     YDNFFDSEEEWLEYELEKLREYIIDYINGKSIEASDLYPIKEFIQHLKFQKVLDRYDD
                     LYSMDMFGESTDGHKYGTPYQVVKMINPNSKEDMELLREVLKDSRFDDEDE"
     gene            130615..130857
                     /locus_tag="KOU88_000287"
     CDS             130615..130857
                     /locus_tag="KOU88_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBK3210211.1"
                     /translation="MGNELLENLDRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     YAEITRKGKNWYITIDNCIITVNKYSYTVITAHKIK"
     gene            130854..131308
                     /locus_tag="KOU88_000288"
                     /pseudo
     CDS             130854..131308
                     /locus_tag="KOU88_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
     gene            complement(131401..131610)
                     /locus_tag="KOU88_000289"
     CDS             complement(131401..131610)
                     /locus_tag="KOU88_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006907144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210212.1"
                     /translation="MYEIESENGRLSYKIFANNEDLQLYLKKNKGKTCKDTKPVFAVE
                     KYKEYANTQIRKLTSDEIQEYMSER"
     gene            131780..132676
                     /locus_tag="KOU88_000290"
     CDS             131780..132676
                     /locus_tag="KOU88_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBK3210213.1"
                     /translation="MQESRLFKIVYYLLDKGKATAPELAEKFEVSVRTIFRDIDALSG
                     AGIPIYAETGCKGGICLMNDFVLDKAVLSEKEKQEILAALQSLSVIGNVYEDATLVKL
                     SALFNTRSETWFEVDFSRWETKTEDNEKFETLKTAVIHHKSAEISYASGDGQYSKRKV
                     QPLKLYYKTNAWYLKAFCTERHDFRMFKLNRILSIKLLNEDFIPTSFPEVQKMPSQTY
                     GKAVLRFSKEVAFRVYDEFSSSQVIRQDDGYLLVTAEMTREPWLIGGLLSFGTQVEVI
                     EPVYLKTQLAEKAKEIYEMNKA"
     gene            132754..133449
                     /locus_tag="KOU88_000291"
     CDS             132754..133449
                     /locus_tag="KOU88_000291"
                     /inference="COORDINATES: protein motif:HMM:NF014573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3210214.1"
                     /translation="MKILIINGSPYKENSTTLKITRAFMEGLNETAEIVHTIDLDINP
                     CRACYACWVKTNGKCVQNDEAIAVLNKIREADLVIWSIPLYCYSAPSHCKALMDRTVC
                     FNSAEMYLGDDECTHHYGYEDGSKKTVLISSGGLPDVKGNFDGLVFQLKRMFGENTAT
                     ILCAEAGLFLSPETEPLTLPYLEAAKKAGTEYKATGLISKDTQMILDVPMIPTDMYIA
                     NVNATFSAMKEKN"
     gene            133991..134152
                     /locus_tag="KOU88_000292"
                     /pseudo
     CDS             133991..134152
                     /locus_tag="KOU88_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728841.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 region 4 domain-containing protein"
     gene            134157..134396
                     /locus_tag="KOU88_000293"
     CDS             134157..134396
                     /locus_tag="KOU88_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3210215.1"
                     /translation="MRKEYGYPTLEVICKASAGSETAIKVILKFYDAYICKLCLRTFY
                     HSESGKITMQVDEELKGQIYTEMMKAILKFEIRVK"
     gene            complement(134580..135071)
                     /locus_tag="KOU88_000294"
                     /pseudo
     CDS             complement(134580..135071)
                     /locus_tag="KOU88_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861120.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(135312..136689)
                     /locus_tag="KOU88_000295"
                     /pseudo
     CDS             complement(135312..136689)
                     /locus_tag="KOU88_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428529.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
     gene            complement(136683..137396)
                     /gene="rgbR"
                     /locus_tag="KOU88_000296"
     CDS             complement(136683..137396)
                     /gene="rgbR"
                     /locus_tag="KOU88_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgbR"
                     /protein_id="HBK3210216.1"
                     /translation="MIKIAVCEDEKETQLLIEDYLENILKDISIEYEIQKYISGEELL
                     ESNLKDIDILLLDIKMEKLNGMDTARKIREVDNEMEIIFVTSLIDYVQEGYEVRAYRY
                     LLKPIELEELKKHVLTCIKDIEINKESHITIKNKSNTYKIYLNEIKYIEVQKKDMLIH
                     TINKNFDIKYSLGKIEKELNPYKFIRCHKSFIVNLRYVENIKPNAAILESGEEVPISR
                     YRYKEVKEKFLKFLGDTIC"
     gene            complement(137646..138206)
                     /locus_tag="KOU88_000297"
     CDS             complement(137646..138206)
                     /locus_tag="KOU88_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HBK3210217.1"
                     /translation="MSAMEKKIKFKFDWYSSPDKIEKWLEDIEAKGYNLYKINKFGGI
                     FYFHKGSPRKIKYTVDYYYDVENNYFDEHKSNGWNLVFRSIGSFMGTSAWYIWSKEYK
                     DIPPKLYSDSDKTNKVKSVLFMNMFVFFMLVVIFIYLLNIEIRNLYSGYGASVTAIVL
                     QIILLILYVVQLYRRLMYYLRLKKFK"
     gene            complement(138302..139105)
                     /gene="zupT"
                     /locus_tag="KOU88_000298"
     CDS             complement(138302..139105)
                     /gene="zupT"
                     /locus_tag="KOU88_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBK3210218.1"
                     /translation="MNNVIFAFLITLLAGLSTGIGSCIAFFAKKTNTKFLSISLGFSA
                     GVMIYVSMIEIFPKAQDALTKSMGEKLGSWSTVIAFFIGMAIIAVIDKLIPQEENPHE
                     IKKMENIEEKNIKKNKSLLRTGIFTAMAIAIHNFPEGLATFISALDDVTIAIPIAIAI
                     AIHNIPEGISVSVPVYYATGDKKKAFYYSFLSGMSEPLGAIIGYVLLRNFLNDITLGI
                     VFAIVGGIMVFISLDELLPSAREYGEHHLSIYGLIAGMGVMAISLLLFK"
     gene            complement(139256..140419)
                     /locus_tag="KOU88_000299"
     CDS             complement(139256..140419)
                     /locus_tag="KOU88_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3210219.1"
                     /translation="MDIKEITKSYKDYVIKLRREFHENPEKSMEEVRTSKRVKEELDK
                     IGIPYVSAGGTGVIATIKGANPGKTVALRGDMDALQVVECTDVEYKSKNEGLMHACGH
                     DGHTSMLLGAAKVLNDIKDSINGTVKLFFQPGEEVGKGARAMIQDGAMEGVDSVFGIH
                     LWTDVESGTISVEEGPRMASADFFKITVKGRGGHGSLPHQGVDAVLASSAIVMNLQSM
                     VSREVSPLEPLVVSVGVLNSGTRFNVIASEAILEGTIRLFNPELRKQIPGILERIAKS
                     TAEAYRADAELEYGYLTPAVINDKECSKIATDAAIKLFGEDCITLFEKVTGAEDLAEF
                     MNIAPGALAFVGARNESKGACYPHHHGCFNIDEDALEIGTALYVQYAVDFLNK"
     gene            complement(140479..141666)
                     /locus_tag="KOU88_000300"
     CDS             complement(140479..141666)
                     /locus_tag="KOU88_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210220.1"
                     /translation="MEAITAFCLVLVSLTIGDIVSAKTKAFVPSVFVSAIIFIVGFWT
                     FFPENIVDLAALGTPLAQLGMLLLITHMGTMMSIKELAGQWKTIVIALAGIVGICVGA
                     LALGTVVFGWDTAVIATPPLTGGLVASIMMADAATAKGLASLSVLAILMYVAQGFAGY
                     PITALMLKKEGKRLLSDFRSGKVTVNTDEEKVKDLPEQKSRFKIIPDLPEKYDTTYMI
                     ILRLGFVAWLAVQFTNLTNEVVSRYVICLIFGVIASELGIVDRKPLNKSGSFGWLMTS
                     LMAFIFAGLAKATPAMLVEMAVPLVGIIIFGVIGMGIFSIIVGKLLGESKEMAFSVSL
                     TSLYGFPPNYILTEEAVKALAETPEEKEFLMDKMLPKMLVGGFTTVTIASVVIAGIFV
                     NLI"
     gene            complement(142029..143729)
                     /locus_tag="KOU88_000301"
     CDS             complement(142029..143729)
                     /locus_tag="KOU88_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210221.1"
                     /translation="MIKQFVKYYKPYKKIFTLDLIAAFLFSLCDLVYPMITRNIMDDV
                     VPNKNLRMLVVFAVALILIFIAKAGLNYFMQYWGHVIGVDMQADMRNEVFTHLQRLPN
                     TYFDNNKSGVTMSRIVNDLMDITELAHHGPEDLFISIVMLVGSFFILIDINIPLTLII
                     FAILPFIIWFAIAKKDKMNIAFMKSRVTIGDVNATLENSIAGMKVTKSFCTEKEELNK
                     FVRSNKLFRRARQDSYKVMAEYYSGMNLYMDILEWVVVIAGGYFTYIGKITLGDFAAY
                     ILYVKMFIQPMKKLINFTEQYQNSMTGFKRFIEIMEQDHQKEAKNPIELENVKGDIEI
                     ENISFTYEDKTQVLDNLSLSIKAGKTIALVGPSGGGKTTLCNLLPRFYEFDKGDIKID
                     GKSIKDVSLKSLRKNIGIVQQDVFLFTGTIRDNILCGNPNATDEEMIAAAKKARIHDF
                     VETLPDGYDTYIGERGVKLSGGQKQRISISRIFLKNPPIIILDEATSALDNVTEREIQ
                     ESLEELSKDRTNLVVAHRLTTIKNADEIIVLTDKGIEERGTHEELVNKNGVYSRLHNN
                     "
     gene            complement(143984..>144258)
                     /locus_tag="KOU88_000302"
     CDS             complement(143984..>144258)
                     /locus_tag="KOU88_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210222.1"
                     /translation="KKILVACGAGIATSTIVCDRVERLVKENNIQAEVEQCKIAECST
                     KQEGADLIVSTTILPTTYDIPTIKATGYITGINTTALDKKILNALK"
BASE COUNT        45417 a        26234 c        15777 g        56830 t
ORIGIN      
        1 tatccactta aacagctcct tttatttatc tttaaatttc atattaagct tatataatct
       61 tatgtacctc tccaagttca ttatcttcac tatcaaagac tttatagatt aaaacatcac
      121 ctctttgtct tttgagcttg taatttattg ttatatctat aattgatttt ttcttcaact
      181 gaaatactac agtgctattt ccataatctc tataattact tattaattct tttatattta
      241 tttcttgtac tgatttttcc attgtaccat caccattcat aaagtaagat atatctccaa
      301 atacttcatc aaatacagaa tgcatacttt cttgtatttc tttattattt tctataaaat
      361 tatccatatg actccataaa gcattaaata gtggcatttc ccaatctgga caatcaacaa
      421 aatctttata tcttcctttt ctccatctat attctccatg atgaacaaag attaattcat
      481 atataaaatt aaaatctttg ctcatttctt ctttagaatg ttttttcata aattcatagt
      541 attcatctaa tatcttttca ttagctccaa tcaattgaca tatttctttt ttagtaaatt
      601 ctttatttat actatcaaat aatggtatta aagcatttcc ataggcacat ataagagatt
      661 cacaactatc aagtaaacct tctaaatagt ttatatactc ttttatctta gtcttattac
      721 caagctcttg ctttaaatac gatttatatt ctcgtatttc atctcttatt ctttccatat
      781 cctttaagtt atctcttatt tcaaacttgt atttcactaa taaattactt aaaaataatc
      841 tatcattaac cttattctca gtaagataaa ttcttgctct atccttttga attccagaaa
      901 aagaatttaa tgctttttcc aatacttctt tttctctttc ttcttttgtt ttaaacgcag
      961 ttatcatatt aattcctcca aaataatcat tttttaatag gatatacaat atttgtatat
     1021 cctattttat ttttatacta ggtattatat agttatatta tacttactta tttctggtaa
     1081 acacatttct ttaagatttt gtactgctct atatttacta ctatatattg cgttataaga
     1141 tttatttatt ttttttgata ttttttctgt gtcatatcct tttagataca ttcttataat
     1201 ttccttttgt ggctgaggaa tatatctaat ttttcttttc actattttca tttgtaattt
     1261 tttctcagct tctatttctt ctgctctttc cttctcaatt ataacttcat ctaccaataa
     1321 gccttcatct tgtataaact ctataagttc tgtatattca ttagaatcta catttttatt
     1381 taaaactaaa atctcatttg taaacttttt tgttttactt ttatttacta atctaagcat
     1441 gttatttttt ataacttttt gaaaataagc actcacatat tctatttcaa ttttataatt
     1501 cattatagat ttccataatc ctgcttgtgc ttctgctatt aaatcatcct tttcaaaaat
     1561 accttctaaa tattttgcat aaatagatgc attaattttt atctctttat caagaacatt
     1621 tagtatatca ttaaaagcta attcatctcc actttgagcc tttctaacta acgttttcag
     1681 cattttattt ttatccatat ttttatcccc cataaattct ataattcaat cttttgccct
     1741 ttaattcaat caaataattt ttactcattt caattaatct acttccaata gcttcatcta
     1801 tttcgagaag ctcatcaaaa tttttttctg ttgatacaat caatggcatt ttatttaaat
     1861 atctataatt aattatttca aacattatat ttatgtcact atttgttata ttgcctttat
     1921 ataaatcatc aattaataaa accttagctg atttatactt tccaacttct cttctataag
     1981 tttcttcatc cattatattt tgctttatta atgtcataga atctctataa ggcatataaa
     2041 taacacttat agacctattc attagactat tagctattgc tagtgataaa tgagttttac
     2101 cacttcctac ttgtcccata aatataattg aatttcttct aatctctctt atttgttcaa
     2161 aataatttga gtactcaata gctttagtaa atgcttttgc tactgaagaa tccacttggt
     2221 aattaaaatt atcaaacttt aatttcctaa attcttcact tactccacta ttttttaaaa
     2281 tattttctgc tatcctaagt ttcctacatt tacattcttt aaaaccttca tcggtttcta
     2341 tgaaaagtct atccttacat tttaaacatt tatattcagt atcttggttc aactccaatg
     2401 tctctaagtg cctgtcttgc tctttcaagt tcgttgtcat tgattcttgt ttctttactg
     2461 ttaaaatcaa attctgtact ctttgtttga gaatttcttt ttccttgttt gtcatttttt
     2521 actcctccca aactattact ttttcttttt ttcttttcat attcattctg atactctgtt
     2581 aaatctaaat ttgtcttcac accggattct atccagttat ttaatatagt ctttatgtat
     2641 ctataatttt taactccatt tgatgttgct tcatcaatag ctcttataat tacatcaacc
     2701 tccattccat catctaaata acctgctagc tctataaaat tattaggtgt aattaaacct
     2761 atataagttt cataatattt ttttatatat gcgctttctt cttgctcctt attaatagta
     2821 ataatagtat tattattttc ttttatacta ttttctttta tgttgccgaa aaactggatt
     2881 tcagttttac tgtcgccggt tttttcgctt cctggttttc cgatttcggg attaaccgta
     2941 ttcggtatat tgaaacacgg ttgactttta acatcttctt tttcttctat tttaatttga
     3001 ggggtatcaa atatatcata tctatatcct tttatttgac ccttatcatt tcttatttta
     3061 cttcttatta caaatccttc atttataagc tcatttaaag cactacttat ccttgattta
     3121 ctatcttttc tataactaat taatgatttt gcatatattt tgtggctccc tgacttttga
     3181 aatcttaaca tttgtgtcac tacccctata gctgaataag ttagattttt attatctaat
     3241 atcgcatttg gaacccttgt aaaagggtct tcaaaattta tatgaaaata tgtttcgtta
     3301 tcaaagttca atatatcacc tacttttcaa tatttttaag tgactcttca tatattttgt
     3361 actcataccc cccaagtact ttacctgtta aggcatctct tcttatctct ctacttacat
     3421 aacctttttc tataagttca tttaaaatat ttgctgttga atctctacca ttgctacttt
     3481 tattttttaa atcttctaag tatattgttt cattttctgc cttagtcatt aaatataaat
     3541 gaagaccctt agcttgccaa cttagattat tatcttgcaa acaagtgcta tttaatgtta
     3601 catgcaattg tttattacac ccttttacaa cattcacaat atcacctaaa ctttctacta
     3661 tatgtataat ctaatttttt atttgcataa tattattgtt ttgatatata atttaataaa
     3721 tataatttat tgttttactg aattgagcct tggcataggc tcttttctta tagctggaca
     3781 tctattggtc tatctctttc aagttcttct tgtattatca taaactccct aaattcagtt
     3841 gatgcttcta actcaatatc atgttcaaga ccctctaata tattttggct agcaaatttc
     3901 acggcttccc accacattaa actactatta ttttttgtac cttgtaatct acttatttct
     3961 ttttcagcct gtttaatttg acctattgct atcaatctag ctgtttccat ttaaatccct
     4021 cctaatttat cataattaca gttctaagaa tcttctaaag ttaataattg ttacacctcc
     4081 tttctttagc agcataacct aaagttaatt cattctaaat tgctatcatt atgacatatt
     4141 taaatctttt aaaatgttag atttcctatt ttaaatctcc ccctttttgt gttatactct
     4201 atttggattt ttttatttat tgtgttggtt actttgacca gcactttttt tatttaatgt
     4261 tccaactgat atttttttac cagttttaat gtccttaaat actatatctg ctaaaaactt
     4321 accatctttt ttaagagtca tcacattttt cttactaata tcaagactaa gcaatttcat
     4381 caccttcttt caaacatact atcgcttatt tattcctagt tgtttaaaaa tagttgtcca
     4441 attttcttct ttgagaaagt gctaagtatt agcaacttct ctactttctt aactttctac
     4501 tgtctcagct ttcttcattg ctatattaat agctacttct ttggctactt catcaaactc
     4561 tttccatctt ctcctattct cttcatcaga tatacgtgga tatactatat aaacttctgt
     4621 gttttgatta gctataattt tttcatcata ttctatgttt ttctcttcat catatttgta
     4681 tggtttaaat tgttgtagta ttttcataac atcacccctt gttataaaat atgagctcat
     4741 aaacttgtct tatacttatt taattattgc aatttttgct taaatcactt ggtattccat
     4801 attttaaagc catatccttt attacaatta cataaccttc tattaaataa ttttgttctt
     4861 gtataacatc cagataatta aatttttccc ttctagactt gcatacacct tcttctgcca
     4921 tttttcttct tctattattt aatcttcgct tcaagtcaac attaaatctt ttacaaagaa
     4981 gttcataact ttcttttcta agagtattta tatattcatt tccacctaag ttttgcgaca
     5041 ttgatactaa taatcttctt gtttcttctc tccaatcagt tgtattcaat gtaactacat
     5101 cttttatgct ttgtatttct tgtttagttt ctgttatctc ttgttttatt tgcttttgct
     5161 ctatttcttg ttttgctaca gtatcaaata tttgtttaaa catttgcaat tctggactta
     5221 attgatttgt aattaaggta tctttctttt tgttaaagta agactcttct aagttatcaa
     5281 actgctccca agctttgtca gtatccaata ttttgcagtg tctgtttgct cctctttcag
     5341 tccaaagata cattttcgaa gtaaatttta ggttttcata ttctgtatga atacctttaa
     5401 aattctttaa atcatcacct tgcaataaaa aataatgttt accttcaata aatctatctt
     5461 tgttattgtt aaaattgttg cttatatttc ttacatctgt ttcatataca tctgctagtt
     5521 gctgtgtagt taaaactctt tcgttatttc tttctattac ttgtaagtta ttcatttttt
     5581 aaccctcctc ataaaatttc tattttagaa atttaattcg taaaaaaatt ttctatatca
     5641 caatcaagta tcttagataa tttaggtaac atatcagctc taattgaata ttgtcctgtc
     5701 tcgtatttaa aataagttga tgcattttta aaacctaact cttttgcaac attttgtaaa
     5761 gataaattta atgtatttct tctttttttt ataaaatcat ggtctatctt tttcatatat
     5821 tcacctcaat ttctatttta gcaatttcta tatttcaata ataacatttc taaaatagaa
     5881 attcaagact tttttatatt tattttagaa attttttatt tctattatag aaaaatatgc
     5941 tattatattt ccataataga aaaattttcg aggtgattat atatgagtgt aagtcaaaga
     6001 attaaatatc ttagagaaaa tatgaatatg tcacaaaaag aattatctga aaaagcaaat
     6061 ataaatacaa gtgttatgaa tagaatagag tctggcgaaa gggcaataag agatgatgag
     6121 ttaatagtat ttgctaaaat ttttgatgta tctactgatt atattctcgg tttatcagat
     6181 acagaaaaac taaatattga tgaaagttat gaatttatag acagtttaaa tagcccagat
     6241 gacataaaag agttaataaa agtaattctt agcttagatg aagaaactag agataaaatg
     6301 ttaaaaatag caaaagtatt tgtaacagaa aaaaacattg aacataatga caattaaaac
     6361 tgaattaatc aaaaatgttt ttaaatgaag atactaattt ataaatataa tatatttaaa
     6421 agagaggaac tacacctctc ttttttcttt ttcttctttc aacatatttt tatacttctc
     6481 aaattctttt tcttcaactt ctttaaaatt tttaaataaa ttatctagtt ctaatattag
     6541 tctttttgta tattccatat actatccccc tgttacaaga acttacgttc ttatttttag
     6601 ttaaaattcc ccaatgaatc ttaataaaat ataactatgt attttcattt ctagaaattt
     6661 tttagattat ttttacatat aatttacaaa ttatttggtc ggtatttata gaccttcaaa
     6721 ataaattttc ttaatattct taactacatt ctaccacaaa tttccacaaa aaaatgttgc
     6781 tattaaccgc attgtttttt tctatatgta aaaaatagat tatctataat actttaggag
     6841 gaaacagaca tgttaaaaga tttaaggatt ttaagaggtt taacacaaaa agaattagca
     6901 aatagaacta actatagtcg agagtatata tctgatttag aaagaaacaa gtacaaaaat
     6961 attacaatac caactatagt tgatttgtca attggcttag aaatcagtcc gctattatta
     7021 gcttgtcatt ttatagatga agagttgaaa aaaagagata aataatatat aaaaactaaa
     7081 aataaaatag agtagtcatg gaccactcta ttttatttat tttataagat tttatttaag
     7141 tctatctgat attcagactc tttcatttcc tttgcaatct taaattcgca cgctccttct
     7201 gaatccatta caatatatac tactcctgat atattagctt cctttacata ccacatagtt
     7261 aatataaaac gtgaaaatat aaataatgta ctaaatttat acaaataatt tacataccac
     7321 atagttaata taaaacatga atctataatt aaaagtggat taggtggtgc tatatttaca
     7381 taccacatag ttaatataaa actaataatt gcagaaaatg taccttgtgc agtgagtcaa
     7441 tttacatacc acatagttaa tataaaacca gatattgaat ttgcagagaa ttatattgaa
     7501 cgattattta cataccacat agttaatata aaacttacat actgttcttt tttttctttt
     7561 agttcatcaa atttacatac cacatagtta atataaaacc tgacgaacat gtttttatag
     7621 caggtatgac aggttattta cataccacat agttaatata aaactcattt aagaaaagat
     7681 tttaatgaaa atgatttgtt atttacatac cacatagtta atataaaact agtaaaatca
     7741 aactatgaaa gaataaatgt atttaatatt tacataccac atagttaata taaaacctca
     7801 aaataaacta agtattttca atatctacac atatacaact cgctcaaatt tgcagtgaac
     7861 catgagtagt gcaattgata agatttatca cataccctca ataccttaca tttcaatgct
     7921 taagccctat tttatcaaaa atatcgctca ctgcaaaatc tctacatttt tattatatca
     7981 aaaaaaatat tatttttgaa tatctgtact aatttgtgat ataataaaag caagaagaac
     8041 tacaatctat tttgcgttag agtggagttc atcataaaca gagtttattt tttggattta
     8101 aatataaatt taaattcaac tcgtaagtca ctctttgtgc gagagtggct ttttgctttt
     8161 ttgaatagtt tactgattaa gtaaactacc acactagctg ttaaactagc taaaacatta
     8221 aacaaaaagt tatccatgaa ctcacctccc ttcgaatcgt tgggaggata atcttttgta
     8281 catgaactcc actctataga ttgtaagtta aatcttcttg ctaaaaatat tataacatat
     8341 tatggtaaat tatataatta aaaacacttg tttaaaagtt ctaattttaa ttataaactt
     8401 tcccagtttc tatatctata aaaaaccaac caaaagtacc attactattt tttgaattga
     8461 ttttaacagc atagacatta ccactatata tatcatctct aaaatctatc atatcaacta
     8521 ctaagttatt gatactgact ttatgtctct tagcacattc ttttaatgct atctgttttg
     8581 cttgttcctc tgttatactt cctttatttt tataatcatc tggattacat actttcatat
     8641 taccattaac atcatatgta taaactttgc tcatatcatt tttagctaca cagtatctaa
     8701 catcaccctc tgcaccctgt ttaatgtaag caaatacata gtactctttt cctgaaaaat
     8761 caaaattttt atctagtaga aatattaaat cttcatcttc tgaataatta ggttcgtaat
     8821 aaaatttctt cacacctaat aattttttca ctgcattagc agcatcttct actgtatatt
     8881 ctcttccagt attagaatct cctatatttt ttgttacatt taaacactgc tgtaatatac
     8941 tatcactcaa atttcctata gcagttaatt tagttgtact tttcaataca cttttattac
     9001 tatcattacc aactaacaca atatcattat ttttagcaat ggtagaacca acaagagcat
     9061 acactaaatc agtaccactt gctatataaa attcttttac tccactataa aatttattta
     9121 ttatcttttt gttagtatca tatctatctg tcccacctaa tctagttgaa ttagtatcct
     9181 taactatttt gtcattcatt gatgaagtac cacctattac ataactttct acaccagttg
     9241 tattaaatgg aacacttttt ccatcagtta atactatagc tgctttatct ctaactgcta
     9301 caggtgcaac actcattgca tcaggctctc ctttaaaagc attagtcaat atgactttat
     9361 ttactttgtt aattgagttt atttcttttg cgacattata gcttgtctta attctatcac
     9421 taccttgaag tcttttaatc tctattcctt tgccttttag aacagtttca gtatatttat
     9481 caatagagtt ttctcctcca attatatata ctttttttgc cttttctaat cttttaagtg
     9541 tagcatttgg tatgttattt ttcttagtca aaagaattgg agcgtttata gctcctgcaa
     9601 gtccacttgc acttaatcca tcagccattg tactgtctgc attaattaat atagctgtag
     9661 tatagttttg tttgtctgca attataccag cagtttcgta tttatctgca cctttaattg
     9721 attcaatttt atcaagagca tttacagata gggcaactag caataaatat agataaagat
     9781 aaccctattg ttaataattt tttaattttc ataatatctc cttctcttaa atattttcac
     9841 ctaaattata taatactttt caggaaaatg ttaccataaa tttaaaaggt tattattact
     9901 taatataata ttaatgaaaa atatcactct taaattaatg actttggtag aatatggtga
     9961 taaaataaaa ttaatgagag acaatataag ggggattata ttatgataat cagtaaaaaa
    10021 ataacagcaa tattagtatc atttttaatt atgatatcaa tggttggatg tgctccaaaa
    10081 gaaagtgcta cagaagtagc taaaaagtac cttgatagta tagaaatcaa agactacgaa
    10141 gtagcatata atttattaag taaagacagt aaggaaagtg tcagtctaga aaaatttgaa
    10201 gaatatcaag atactttatt taaacttcaa accctaaaag attataaact tggtgaagaa
    10261 aataaagtag agaaatacaa atattctaat aaagagtaca caaatcttgt taaaataaaa
    10321 gaaactgata ctataaagta tatcactgaa aataaagaag atactgcaaa ttttgataga
    10381 tattttataa tcgaagataa tgaatataaa ttattatggc ataaagactt taaaagagct
    10441 cttagctcta attatgtcaa aatcgctagg tcagaaacag aaaaagatga agataaggat
    10501 tataataaag ctgctattga tatcaaaaaa gctatagaaa ttgatgataa aaatccactt
    10561 gcatattata cacaatcata tatttatata gagttacaac gatatgatga ggctttaaag
    10621 tcaattgata aatacttaga atatctagat aaaaataatg aagcttataa aatagacgct
    10681 agtgatgctt acaatttaag aggtgttatt tttatgagta aatcagaatt taataaagct
    10741 agagaatctt acaataaggc gcttgaactt aacccggata atgaatatgc aaaaactaat
    10801 ctaaatgata ttaaaggatt ataaggcatt aatattatag aaaataagta tgttgaaagt
    10861 taaattaact tttgacatgc ttattttcta tattttaaac tctattgatt tactatataa
    10921 tagtgcataa ggagtgtgat tacttattat gagtgttgcc atatacttaa gaaaatcccg
    10981 tgctgatgaa gaggcagaaa aacaaggcga atttgaaact ttaagtagac ataaatcaac
    11041 cctactaaaa ctagcaaaag aacaaaactt agatgtaatt gagataaaag aagaattagt
    11101 ttctggtgaa agtataatac atagacccaa aatgcttgaa cttctaaaag aagttgaaga
    11161 aaataaatat gatgcagtct tagtaatgga cttagacaga cttggtcgtg gagacatgaa
    11221 agaccaaggt atcatattag aaacattcaa agaaagtaag accaaaatca tcacacctag
    11281 aaaaacatac gacctaacag atgaatttga tgaggagtat tcagaatttg aagcatttat
    11341 ggcaagaaaa gaattaaaac ttatatcaag aagaatgcaa agaggtagaa taaaatcagt
    11401 tgaagaaggg aatttcatag gaacctctgc tccatttgga tatgatgctg taacaactgg
    11461 tagaaaagaa agaatacttg taccaaataa agatgctgat gtagttaaga ctatctttga
    11521 cttatatatt aatgaagata tgggttgtag taaaatatca aaatatctaa ataacttagg
    11581 cattaaaact gctacaggtg ctaattggta caattctgca attacaaata taataaaaaa
    11641 taaggtatat tgtggctaca ttcagtggca aaaaaaggac tacaaaaaat ctaaaaatcc
    11701 aaataaaata aaaacagtta aactaagacc taaagatgaa tggattgagg caaaaggaaa
    11761 gcatgaacct ttaataagtg aaataacatg gaaaaaagct caaaatatac tcaaaaaaaa
    11821 tggtcatgtc agctatggta atcaaataaa aaatccactt gcaggaatag tgatttgcaa
    11881 aaattgtggt agaccattag tatatagacc atatgcagac cacgactata taatttgtta
    11941 tcatcctggt tgcaataaaa gttctcgatt tgaatttatt gaagctgcca ttttaaaatc
    12001 tttagaagac actgtaaaaa aatatcaatt aaaagcatct gatatagact tagataaaaa
    12061 taataaagat agtaatatag aatttcaaaa acgagtctta aagggcttag aaactgaatt
    12121 aaaagaatta ggcaagcaaa aaaataagtt atatgattta ctagaacgag gaatatatga
    12181 tgaagataca tttattgaaa ggtccaacaa tataagttca agaactgaag aaattaaaga
    12241 ttcaattaag acagtaaaaa atagattaag tactgttaaa aaagacaatt ctaaaataat
    12301 agaagatatt aaaactgtgt tatcacttta ccatgattca gattcccttg gaaaaaataa
    12361 actcctaaaa tctgtaattg ataaagcagt ttattataag tctaaagaac aaaaactaga
    12421 ttcttttgaa ttaatggtcc atttaaaatt acatgaagac cagtaatacc aataacatat
    12481 aaagagtagt gtgtaatgaa ataagtcttt tagatatact tggtacagag gctaactatg
    12541 ttcttgatga agttgaacta aaagttcaag ttggaaaact ttacgaacaa ctaaacaaaa
    12601 ttcttactcc tagagaaaga gaaattgtcc agttaagata tgggttaact ccttatggct
    12661 ataagacaca aagagaaatt gcacaaaaac tcgatatatc aaggtcatat gtatctagaa
    12721 tcgaaaaaaa agctcttaaa aaactagaaa aagagcttgt tcaagaaagt taatactata
    12781 ttttaaaagg atatatcgta catcattaga caaaattttc tatctaaaat caaagttacg
    12841 atatatcctt aaattttata gtacataatt tattttatac tttcacatat ttccttaaat
    12901 ataggtgttg cagatttatt tcctttttga gttccttcta ctaacacagt tattacatac
    12961 ttaggtcttt cttcaggata aaatcctgtt atccatccat ggtctatagc ttttttattt
    13021 aaactacttt gagctgtacc agttttaact ccacaaccac cttcaatatc ttttaggtct
    13081 ttagctgtac caatcctaga tacagacttc atatattctt taacttgtgt acacacataa
    13141 ggagaaataa gttcttcttt ttttgaagac ttataagttt ttattgtatt catattattg
    13201 tccacaagac ttttatataa gtatagtggt ttgaatgttc cattattagc tattatttga
    13261 gtcatttgat ttatttgaag tggtgtaaat tctatatttt cttgacctat agctaaattt
    13321 cttattgata tgttttttgg agcttctcta attttttctt catcaagacc aatatcaacc
    13381 ttttcaaata aatgtaattt ttcagcagat ttgagtatct tttcttttcc aagtttcata
    13441 gctatatcta aaaatgcagg attgcatgaa ttagaaaaag cttgtcttaa gttttggaaa
    13501 ccatgaccat ctcttttatt acatcgcagt atttcattag tattcccaac tttagtctta
    13561 cctgtacagt tgtaagtata gttctcatct ataacaccat tttcaagtgc agaaaataaa
    13621 actaccatct taaatacaga ccctggtgga tatgtcgctt ttataactct attttcaaat
    13681 tctccatttt ttccttttaa actttttgat atgtcatttt ggtcaaaatt aggtctagag
    13741 cacattgcaa gaatttcacc tgtagatgct tccgagatta ttgctgctgt aggattttct
    13801 tctttattta gtatttgttc taattttttt tgaatgttat aatcaatagt agtttttaga
    13861 tgtctatctt tatccttatt atcaacagtt tttacacttc cctttagtat gtttagagat
    13921 ttttcatttc ctgcatctcc agctttaaaa gcacttatat acttttcatt tgaatttcta
    13981 agtacactat ccatactctt ttcaattcct gattgacctg atttatcatc ttcttttata
    14041 tatcctattg tatgtgataa taaaccatct tttgcgtacc tcatagtttt ttcttctacc
    14101 attattccat ttttctcaag ttcttttttc atactcttat cgatattttt agtctgaatc
    14161 tgtattatag ggcgtgtcaa ttgctcttgt acagctttat atatatctaa atcattcatc
    14221 ttagtagctt tcttaataag ctccaaaatt ttatagttat tatttaattt ttctttttca
    14281 acaattaata cctgagattt acttgtatct gtaagcttct tgttgtttct atcatagatt
    14341 attcctcttc cactatttaa ctcgactttc tcaacgcttt gtgattcaac actttgtttg
    14401 tatttatcac cttttaatac ttgtatatca actagcctat aaattaaaac actataaatt
    14461 attaaaatta tagtaaatat acaccagctt ctctttccca cttttttcaa aaatggagtc
    14521 ttcttttttg acatgaaatc accccttaga taatttcatt attgacaatt tctaaggggc
    14581 taatactatt tttatcaatt ttttattatt cttcaacctt ttcttctata acttttctaa
    14641 gcatataatc tttaccaact tttactgata gctttaactt cactatttgt ctaggatgag
    14701 gagctgattc tatagcttct ccttcttcat tgtacatttc ttcaatttta gtaaacatag
    14761 tttctttata tggtcccata acttctattt catcaccaac acacatttta tttctttgct
    14821 caacaacaat aagaccatct tcatcttctg tttctctaac tatacctata aaatcatagt
    14881 ttctaacata tgatgctgat tgataatttt ggtcttctgt tgttggttta ttcaagtaaa
    14941 aacctgatgt aaaatgtcta tgactacctt tttttagttc ttccatccac attggattga
    15001 acttccagtt ttctgggtct ctgtaaaatt catctattgc cattctgtat gctcttacaa
    15061 cagtagctac atagtatgca gtcttcattc taccttctat ttttaaactt gttataccag
    15121 atttgattaa ctctggtata tactctatca tacataaatc ttttgagtta aagaagaatg
    15181 tacccctttc atcttcgtat attggaaaat actcaccagg tcttttttct tccaccaaat
    15241 gatattgcca tctacaagat tgagcacaag aacctttgtt tgcatctctt ccagtcatat
    15301 agttgcttat taaacatctg ccagaataag aaatacacat agcaccatgc ataaacgctt
    15361 ctatatccat atctaaaggt gtttttgctc ttatctcaga tatttcatca aaagataatt
    15421 ctcttgccac tacaactctt tttattccat gctcgtacca gaagtttgca cttagataat
    15481 tggttgtatt tgcttgtgta cttaaatgta tttccatatt cggaattact tttttaatga
    15541 cactaagcac tcctgggtca gctattataa ctgcatctat tcctatctct tctagttcca
    15601 acaaatagtc ttctaattgt agaaaatctt cattatgagg tattatattt actgttacga
    15661 atactttctt gcctctttca tgtgcaaaag ctactccctc tgccatatct tccttactaa
    15721 aattcttcgc tgcagacctc attccaaaaa tttctccacc tatataaacg gcatctgctc
    15781 catatgttat agctattttc aatctctcca aatcaccagc tggagctaaa agttctactt
    15841 tatttaattc catctacatc acctctttta ctttctttat aacttagtgc tacaccatca
    15901 cctattggta ccaatgatgt gcttaaatag tcacaattac atatataatc taaataattt
    15961 ctcattcttt taactatagt cttttttctt cttacaacaa aatcatcatg agcaaccata
    16021 cctttataca aaatattatc agatactaaa agtcccccat cttttaattt atctataact
    16081 aaatcaaaaa atagcttata ttgacctttg gctgcatcta taaatataag gtcaaattca
    16141 ccttggactt gactaagttt ttcttctgca tctccttcta gtatagttat gttattgtca
    16201 aatccagcta attttatgtt ttcttttgct ttttctatca ttttttcatt tctctcaaca
    16261 gttattatat ctgcatcttt tcctataata gttgcaaaaa aaatagaaga ataaccaatt
    16321 gcacatccta cttctaaaat tctctttggt ttttgaacct ttaacaagac ttttaataaa
    16381 tctgaaactt ctttatgtat tataggaaca ctattttcct ctgcataaat ttctaaatct
    16441 tttaaaaatc cttctttttc ttttaatgtc actcttatat aatcttcaac caaatcatta
    16501 actatattac tcataaaaac actccctaaa ataataaata ttcaagtttt atattaattt
    16561 attatttttt aaattcatat tgttatatat atttacactt tctttattat aaatctaaga
    16621 ataacaattt tcaataaaaa agcccaacat tattcttacc ctgttagact ttttataatc
    16681 atggtttatt tttttgtatt ttctttattt gttgcttttg tatcttttga ttgtttatcc
    16741 cttgcttctt tatattcttt aacgtatttt aaatggtctt gatagtttgt actataatta
    16801 tttccaccat caatcttagc tacaaaatat aaatagtctg ttttctctgg atataatgct
    16861 gcttcaatag attttatacc aggatttgat attggtgtag gaggtaatcc cttattttta
    16921 taactattat atggtgaatc aatttttaaa tcatcatatg ttacaatttt ctttctctct
    16981 tcaaatatat attgtattgt agcatctgat tgaagaggca tacctacctt aagtctatta
    17041 taaaacacac ttgctattat aggtctgtct ttgtcaagaa cagcttcttt ctcaattatt
    17101 gatgccattt ccattacttc ttgaagagtc atatttaatt ctttttgttt ctttttaaac
    17161 ttgtccgtgt atttactgtc aaatactttt aacatttcgc ttaaaatatc ttcttctgat
    17221 tgtttctttg aattaaaata ataagtttct ggatacaaga acccttctaa agaggttatt
    17281 ccatcttcct tcaaatatgg aaatttatca taaaattctt gaggtttttt tattaaattt
    17341 tcaaaagtag ctttatctcc taaattttta cttactaaca ttgctataat ttctttagat
    17401 gtagctccct ctggaatagt cacttttata ccatcctgat atattttacc tgaaactaaa
    17461 agacttatta tatcattgtt tgaatacgat tgattaagta agtatgttcc tgattttata
    17521 gacggagctt tattgctaac ctttaccaaa agtttaaata atagttcatt ctttattaat
    17581 ttattttcat ataatatgtc agatattttt ccaacagatg ctccacttgg aacgtcgata
    17641 attacatctt ttttgttatt tttatcataa ggacctattt gtataaacac aaatatacct
    17701 gctaagataa tcaaaataac aattattaat actgctattt tcaatctatt ttctttaaag
    17761 ttcataatat aatctactcc ttatgtatat ttatccattt tctattataa aactagatac
    17821 tttaattttc aatcatcttg tagaataaac ttatttatat tgtaaaaaat gttttaaaat
    17881 atatattttt ggtataattt atagtctatc aaaaaataaa aaacctaaca ttatttttga
    17941 catgttaggc cttttataat cacttttcta aaattttcta aaacttttta atctcttctt
    18001 tagttacaat accatatatt aatttatttt tttctatttt tgaatctaca atagagtagg
    18061 aatcaataaa tcttcccttt gccaatgaaa gcttttgttc atcattataa tacatgtaag
    18121 ctaaaacttc accttcattt acataatctc ctactttctt ttctaaaatt atccctgctg
    18181 ataaatctaa aatatcatct ttagtttctc tacctgctcc aagaatcata gccgatacac
    18241 caacatcttc agctttaatt ttgcttatat aacctgattt agttgattta actggatatt
    18301 tatactttga ttttttgaat aaagaataat catctactac atctttatta ccaccttgat
    18361 tctctataaa ctctttgagt ttttgtatag cagtaccaga ttttattgat tctcttattt
    18421 tttcaacacc atcttcaaaa tcatgtgcta cctttgataa aaccaacata tatgctccta
    18481 atacttcgca tagctcaaca aggtctttag gtccatttcc ttttaatgtc tcaattgcct
    18541 ctataacttc taaagagttt cccactgcaa aacctaaagg ttcatccata tctgttacaa
    18601 tccctattgt atctctattc ataccagtac ctatatcaac catagattta gctaactcaa
    18661 aagactcttc taatgtcttc ataaatgctc catcaccagt ttttacatct agcacaattg
    18721 catcagctcc tgaagctaac tttttagaca ttacacttga tgatatcaat gatatattat
    18781 caacagttgc tgtaacatct ctaagagcat atattttctt atctgcaatt gctacctttg
    18841 cactttgacc acaaactgct attttagact tatttacaga atcaataaat ttacttatct
    18901 ccatttctgt cgaaaaacct ggtatagact ccagtttatc aatagtacca ccagtatgac
    18961 caagacctct acctgacatc tttgcaactg gtgctccaca tgaagcaacc aaaggtataa
    19021 gagctatggt agttttatct ccaacaccac cagtactatg cttatctacc tttattccat
    19081 ctatctcaga taggtttatc atgtctccag agttcatcat tgcttctgta agatgtacag
    19141 tttcctgttt attcatctta tttaaataaa tcgacattaa tagtgcagaa gcttgatagt
    19201 caggtatatc tccctttgaa tagttttcta taaagtagtt tatctctttt ttactaagct
    19261 ctaggttatc tctctttttt tttataatat catacattct cataattgaa atctccattc
    19321 taacctataa taatttaaat aaatattaaa ctttaaaaca ctttcaaatg ttgtagtatt
    19381 ataaaaaaac tgtcctttat tagaaataac tttctatatc aagacagctt tttattaatt
    19441 cttttcaaat taaacattaa ctattttatt ataaacttcc tcaaaaaatc tataataagc
    19501 tttaacttat aaatttttaa ccgttgtttt aactaaattc ataaattctg atttaacttt
    19561 ttgagtagtt tctattactt cctcatgact tagtggttga tttaagatgc cagcagccat
    19621 atttgttata caagatatac caataactcc tatattagag tgagaagcta ctatgacttc
    19681 tggaacagta gacataccta cagcatcagc tcccaaaatt tgtgccattc tcacttctgc
    19741 tggtgtttca tagtttggac cactaaaaaa catataaacg ccttctttga catctatatt
    19801 acattcttta gcgcagtttt taactacatc tacatattta gaagaatatg catctgacat
    19861 atctggaaat ctagcaccaa atctgtcatc attttttcct actaatggat tacttccact
    19921 aaagtttata tggtctctta taagcatcaa atctcctgct ttaaattctt tatttacgcc
    19981 tccagcagcg ttagttacta taagaatctc gactcctaat tctttcataa cccttactgg
    20041 aaaagtagct tctttctgag aatatccttc atagtaatga aatctacctt gcatagcaat
    20101 aacttctttt ccttcaagtt ttccaattac aagttgtcca gcatgtcctg ctactgttga
    20161 tacagggaag tttggaattt cactatattt aattgtgaca gggtcttcta tatcatttgc
    20221 taaatcacct agtccagaac ctaatatcaa accaatctta ggttttatat tacttttaga
    20281 atttataaat ttactacttt gtgctatctt ttcaaacatt ccaatctctc catcctatta
    20341 agctaagttt ttatcatttt ataatttaaa ataaatcttc tttaaagctt gacccatgtt
    20401 taggcaactt tacatttagt atatctgcaa cagttgctcc aatatcagca aaagtatctt
    20461 ttactcctaa attaaaacct tttttaatct tattgccata aatcataaca ggtatatatt
    20521 ctcttgtatg gtctgtacct ttatatgttg ggtcatttcc atggtctgca ttgattatta
    20581 aaatatcatc ttctctcata ttagccatta tttcaggaag tctactatca aactcttcaa
    20641 gagctttctt atatccttct gggtctctcc tatgaccata tttagaatca aaatcaacga
    20701 gatttgaata tattagacct ttattatctt gtttcatata atttaaagtt tcatccactc
    20761 catccatatt gcttttagtg tggatagcat ctgtaattcc ttttccatta aaaatatctt
    20821 ctatttttcc aactgctaaa acatcaagtc ctgattcttt tatattatca agaactgttg
    20881 gttcaaatgg gtctagtgaa taatctcttc tatttgaagt cctcacaaac tcaccttttt
    20941 tcttacctat gaatggtcta gcaattactc tagctactgc attatccccc atcattattt
    21001 ccctagcgat tttgcacata ttatagagtt cttctagggg aattacttct tcattagcag
    21061 caatctgaaa tacactatca gctgatgtat atactattac atctccagtt tttatttgat
    21121 gttctccata ctcatctatt attacagttc ctgaagctgg tttatttcct actacttttc
    21181 ttccagtttt tttctcaaac tcttctatta tctccttaga gaatccatgt tcaaatgtct
    21241 taaatggttt gtcaactatt ataccagtca tttcccaatg acctgtagta gtatcttttc
    21301 cctgagacat ttccttacac tttccaaaac aacctattgg ttcttttata ctttcaaaaa
    21361 aatctatacc atctatgttt cctataccta aatttctcat attaggaatc tgaatatctg
    21421 gatattcctt aaatatattt ccaagggtac ttacatcctt actatcacca aatttttcag
    21481 catcaggcaa tgctcctatc ccaacactat caattacaat ccaaattact ctgctcatat
    21541 aaatatgctc cttctaaatt ataaaatttg ctatatagtc tatttagctt ctgctttttg
    21601 taattctaca tcaacatcat ttctaggatg tttctccttt atttctcttc tcacgttttt
    21661 atctatatga tttaaatata cttgcaaact agataaatta acatttccta aaattttact
    21721 tacaacagca atgttagcac cttcatttaa caaatgaata gcaaatgaat gtctaagcat
    21781 tgtaggattt atatttttat ctatattggc tagattagaa tattttttta tgactttcca
    21841 aagaccttgt cgtgtaaacc tttgacctaa tgaacttacg aataatgatt tttcaccttc
    21901 tacagccatt ttaggtcttg cttcttttag atacttttct aagtaaagtt ttgtaatatc
    21961 acaaagtggt atcactcttt gatttttaca acatgaatta caatatatat aatcaatatc
    22021 taggtcaata tcctctatat tcatctctac taattcagat acttttatac cagtaccata
    22081 taatacttca aaaatagcct tgtccctaat caatttaggt gttgttaact ttggaaaatt
    22141 taatagtctt tcaatttctt cttctgtaag tatatttata ttttcttttt ttattttagg
    22201 tttttttata tcctttgcag gattatttgt acatatatga tttaaaaata aataatcatg
    22261 aaaagatttt atagaggata tcatcctcgc tattgtagct attgatacat tatctttttc
    22321 caactttatt aagtaactta taatatcatt ttctactata tctactagtt taatgctttt
    22381 ttgatttata tattccatat atttttttat atccataaag tatgatgcca ctgtattctc
    22441 tgataatttt tttttatctt ttatgtaatc tatatatccc tctataatat ccattataaa
    22501 ctcctttatt tagctaggaa cttaataata ccaatacttg cagtatttaa tattaattgc
    22561 aaccccaatg atagtgctat tataattata atatttagta tatacctctt aattaaaaat
    22621 tgcatatttt ttctattttt ctttttaaat tcataaacca tttctttaaa ataacttaaa
    22681 ctaattaatg ctaatatgat tgcacatgga ataataatca aatttttaaa taatattatt
    22741 aaaatcattt ttatactttt aaattttaat gccaatatac aactatttat tgtataacca
    22801 attgacatcc cttttaatac aaaagctacc aacactgctg gaattgttac tacaaataga
    22861 cttaatagag ctattgagcc cataaagatt gcatctgatt ttaaattttg tatcactgta
    22921 tcttttatgc ttatatttag attataatac tctacagcag gatttatatt gtttaatata
    22981 ttgttactag aacctggcaa tattttattt atgtaagacc caacaacaat agacatcata
    23041 aacaacaatc ctataataat tatttgtcta tttaattctc taaaatcatt ttttctatat
    23101 gttcttctca atttaattcc cccttgtcct ttataaaata atatgcttta ggacaaaggg
    23161 ttattcattt tataaatatt aatttttaaa catatctttt actaataata atccaataga
    23221 tgtttttgca tcttcaacgt cattttttaa taccatgtta tatgcttctt caagctcaat
    23281 ttcatagaca tctaaaaact catctgcatc taaattattc tctcctggag taagacctgt
    23341 tgctaaatat acaaacatta tctcattaga aaaacctgct gaagtgaaaa atttatgtat
    23401 tagcttaata ttttttgcac tataccctgt ttcttctttt aattctcttt cagcacattc
    23461 ttttggactt tcattttttt ctagtttacc agctggaatt tcaaagattg gcttttctat
    23521 aggttttcta aattgcttaa ctaacacaac tttattatca tctgtgattg caactattcc
    23581 tactgctcca ccaacttcta ctaactccct tttttgatat ccttgccctg gaatttcaac
    23641 agtatcaacc tttaaagtaa ttactttacc tgtataaacc ctatcactac taatagtttt
    23701 ttcttctaat accatcttaa acctccatta agtaatatgc tgctgtgctt gcagctttga
    23761 aaaatgcctc atcttgttca taatttcttc ccatactctt tacttttaga ttaaaatagt
    23821 ctaaatcctc tttcgtttta ttattatcta tataaattat attatgcttt ttgtctaaac
    23881 catttaaatt gatttgctct tttataaagt tcaatttttc atcatcatat atagttattg
    23941 gtatgtctac atttacattt acaatttctt taaatacagt catactatga tgtgaaatac
    24001 cttgatgtct ttctcgtttg tcagcaaaac taattcttgg aattgcaatt gctcttcctt
    24061 caagtttttt tacagcatca agaatagagc cttgttcaat ccctgtaaat ccatattttg
    24121 ttcctgtccc agcaattcca ggtcccatac tgacaaatac tgcatccgct tttagtattt
    24181 cttttgctgt aattaatgca gtatatatat ttatacattc ataatctcca ccaaacgcat
    24241 ttcctatagt tattgtacta tctattaatt ttttttcttt taaagtatcc acatttttac
    24301 ttaaataaat tggaagagat gctccatcag tcattatata cactaatttt ttatttggat
    24361 tatttctttt aaatgaagct gcaaatggag ttaacatact atgaagagtc cctactacaa
    24421 cagaaagacc ttctaatcct ttaaaattcg caaatttatc atgataaata ctttcttgtt
    24481 cctcaacaga atccactttt atttgaagag gcgtatatct aagtttcatt atatgtccac
    24541 cttcagttaa agtagattct atattattta aattagttat tacaaaatgg tatccacctg
    24601 tacctaagct cagttctact gctgttgtat ttaaaaccac ttcgtcacct atatttatag
    24661 ttccagatat tttgggataa ttatatgccc tttgtatttc tccatttata tttactctta
    24721 tatcatctag tgtttcagtt tgacttacta ttgattcaac aatccccact cttttgctta
    24781 tcataatact accttcccaa tttatctata aaatttaata gtttattttt ttctattatc
    24841 ttagttaatg agtatttctc agtgaatata tgcataataa ctacaaatat taaccatcct
    24901 aatctaatgt taaatggata cccaaaagaa atgagcattc caatagatat tccaaggacg
    24961 tttgaaccag tatctcccat catagccctt gcttttaaat cataattaaa gtatgcaagt
    25021 acatttggta ctataagtaa tggaagaact tgaacaaatc ctgtcaatgt taaaaatata
    25081 attaccatta tgaataaata tgcttttatt gcccttcctg gtcttaaatc caaaagattc
    25141 attaaattag ttgatagagc tattattagt gtatttacta ttatatcaat tatgtctttt
    25201 gatatagcaa cagaaactat aagccctaca aatccaccaa ataaagcttt aaaacctcct
    25261 gttgtaagac ttcctttaaa taaactttta aaatgcccct ttaaaccact tacatctcta
    25321 tttccaatga catcatctag tatccctgca aaaaacatgg atatcatacc aaacataaac
    25381 ataaatatat acgctaaatc cttaaattct gtagtaaaga aagcaagtat tattccattg
    25441 attacaatca taggcaaaaa tacaattccc atacttactg gtatcatatc ttttttatag
    25501 tttggtctaa gtacatttcc atttatcaat aaatttttaa atagtggaat tacagcatag
    25561 gttccaaata atccagttaa taataaaatg gtataaagta tataatcttt cactaagata
    25621 ttacctccat tctttctttt tttgtcctaa aacctttttt atgtgataat actgtttccc
    25681 tctatgaata aaacctttta aatttcttcc tgtttcatta tgagtcatat ttactaatac
    25741 ttctttaatt ttaaatccat actttaatat atcaatggtc attccaactt ctactccata
    25801 tccaaaaggt atttcatcaa acttttctaa aacttctctt ttaaatattc tttgacctga
    25861 taaagttgca tctaactcaa caccagtcat ctcaaacaca gaatttttag ctaaaccttt
    25921 tacaaatccc aaacctcctt ttctctttgc aggaggaaac ttggctattg taacatccgc
    25981 ctcaccattt aatataggta ctattaattt ttcaacttct ttagcagaac ttcctaaatc
    26041 tccatccaga aaacctataa tatctgcatt tttcattgct aatttgatac cataatttaa
    26101 agcatatcct ttacctctat ttttatctaa cttaaaaaat ttaatctttt cattttctag
    26161 ctcagataca accttagcag tattgtcaat tgaaccatca tccacaacta ttatttcatt
    26221 tatttgctta atgtccaata tgctttctaa tgtatatttt attctacttt cttcattata
    26281 agctggtatt attatactta tataagaatc cattttttct ctccttaaaa ttatttctat
    26341 ttaatagatg gcaacaatga agttgcagta tccaatctac caaaattacc aactatatta
    26401 ccttgttgta gaagaatagc tagagatata cttcctatac cttcatcaat attgtctata
    26461 gttgcaactt tgtttttaga atatagttct acataagaag ttttaactcc tgtattttga
    26521 acttctacta aatatttatt ctctgattta agttttgaaa ctacaaattt ttctattttt
    26581 tcaaactgtt ttgtactgtc ttttgcatca tttccaccag ctattacaac ggaatcatat
    26641 tttagatatg tatctccaat aaaattaaac tttattacat ctagttcttg aagatatgtt
    26701 aaaatgtcac ttgcatcttc ctttttaaga gtgtcaatta tataattaac tgcatcattt
    26761 gcatttttta catctgtacc tagtttagtt gacatttcct ttaacttttc tggatttgtt
    26821 atgttttctt ttaatattat attaaatgca atgcttccat tagatttatt tattatgtct
    26881 tctatatttt ttgtataatc gtcattttca ttagcagata ttattcctat acttttacca
    26941 ttcagcgaac cagctaaaat cttatctaca tttttattta taaaattaac tgcctcttca
    27001 taatctctat ttacacttgc taagtcactg tcaagtttat catttttttc ttttaagata
    27061 tcaaacttat catccaaatc atttattatg tttgcttgtt gttcacttaa ttgttgatta
    27121 ttatttaaat taaatcctac taacatgcct atacccaaag ctataaatat agcccctata
    27181 gtgactatat aatatttcat attaatatgc atatttatcc tcctaaaatt tacatctgta
    27241 ataatactct aaactttaat tgcattagtt gtatgaactg ttgaactcct ggtgacaatg
    27301 atgcaactac caacacagga aataatgctg ttgctattaa tgcccatatg tactttattt
    27361 ttaatttact tctgtataac aaattaacgc ctttagcatc tataagcttt gaacctattt
    27421 ttagtctaac taaaaaagta cttgccatac cttttcttcc tttttcaaga aaatcaatca
    27481 tatttgaatg tgtaccaact gctactatta actcagcctt atactcataa gcgataagca
    27541 tagctatatc ttcactagtt cctggtgcag gaaatacaac tgcatctaag cctaattcct
    27601 caaccctttt aagacctggt gctcttccat ctgtataagc atgtactact atttcactag
    27661 ccttttttaa agcttcatca cttacactat ccatatcacc tacaatcaca tctggagtat
    27721 atccaaactc aattaaagcg tctgctcctc catcaacacc aaccaatact ggctttacct
    27781 cttctatata agaaagcata gtacttaaat cttctttgta gtcctgacct cttacaacta
    27841 tcaatacatg tttattagca taattagttt tcacttttgg aatttctact tctccaagta
    27901 taaatccttt ttctttttta gcataatcta tagtattatc tataaatcta tccaattcta
    27961 cagctaaatt ctcataggca gcctttattt ggtgtgaaac ctcatacttg tctaaaactt
    28021 ctcctgcacc taaaaatttt ccttttctat atatctttcc atctacaact tctatagttt
    28081 ctccttcttt taattcttca aataactctt ctccaacatt atcaattatt agtatattat
    28141 tttcagttaa tatccctgga cctttattgg gatacctacc acttatagaa ggagccgcat
    28201 ttatgacaag ttttatttta gcttctacta aagagtttgc agcaacttca tctatgtcta
    28261 tatgatttat aactgctatt tccccacttt caactctttt agcaagtttt ttggtttttc
    28321 gatctacttt tataggggcc tcgactctca tatttaaacc tccactatca ttattaaaat
    28381 cacattatat tatagcatta cttaacaata aaataaatgt tttaagtttg ttttgcatct
    28441 ttggcattta caatactata tttcatcatt tttttattta acatattcca taatacgctt
    28501 aaaaatacaa agtttacctg catcaaagtc aatatttata ttaaaaaata aaccactgtc
    28561 agtttacaac ttgtaaagac acatactata tccatagtat aataaagtta ttatattgat
    28621 atagtaagca aataataaag aaaattttta tatttattaa aatagcgaaa cggtataacc
    28681 ctagtggtta taccgtttcg ctgcttgtaa tacgcattta tagccaatgc cttaattaaa
    28741 aagccttact ttttatgtct tgtttattta accatactat gttctagtct taatttatca
    28801 gcaatcattg ctataaattc tgaattagtt ggttttcctt tagtattgtg taccgtatat
    28861 ccaaataatt gatttattgt gtcaactttt cctctactcc atgcaacctc tattgcatgt
    28921 cttattgctc tttcaactct acttggtgtt gtattgaatt ttttagctat acttggatat
    28981 aactcttttg ttactgcacc taaaagctca acattatcaa taaccatttt tattgcttct
    29041 cttaaatata aatatccttt tatatgagct ggtactccta tttcatgtat tatatttgtg
    29101 atttctgtct ctatatttcc tacattctta acaaaatcac ttctagtcat ttgagtctct
    29161 tgaactggtc taggttttgg ctcaacttgt gtaactctat tagaaactag ctctctaatt
    29221 ctgtttataa acacaacaaa atcaaatggc tttactatgt agtaatctgc tcctagattt
    29281 attgcgcttt gagttatctt atcttgacct actgctgata gtactattat ttttggcatt
    29341 ttaggtatat ccatagtatt caatttttca attacaccta atccatctag atgtggcatt
    29401 attacatcta gtattaataa gtccggttgt gtctttttta ctaagtctaa tgcttcaatt
    29461 ccatccttag ctatgcctaa tatatcgata tcatcttcat tagacaaata ctcttttaat
    29521 acctgacaaa aatccttatt gtcatctgct aaaactattt tgattttttc cactaaaaat
    29581 ccccccatta aaaaacatct tcttattaca gaaaactaaa ctttttacac aattgcttcc
    29641 taattatcta ctctaaagca tattcgacac tccaaaatta tattcctcct agataattga
    29701 taaaataata aaatttttta atgcctcacc tacaatttta tcatttcatc tataaaaata
    29761 ccatatcctt ttttcggatt atctctaaaa acatgagtta ttgcaccaat aattttatta
    29821 ttttgtatta ttggagctcc actcatcccc tgtacgatac ctcctgtgta ttccaataac
    29881 ttgtcatcta ctacttttat taccatatct ctataatttc ctttatcata tactatactt
    29941 tctattttta tatcatagct tgttatattt ttgtttttat cctcaaaaag aattactgca
    30001 tctcctattt ttacatcttg cggtcttcca acttctatta attgcttttc tttatttgct
    30061 acattaaact ctttattatg gttttctgta atattaccac ttatgcctaa ctctgaatta
    30121 tttgagaaat tacccattaa attgctgtca ttaaaatctc cttttatttt acctactttt
    30181 tcattactag cttttactat ttttaattgt tctggcttat atatatatcc ttgctttatc
    30241 tttaatagtt cattagtatc cgaatctttt atggcatgac cgattgcttt gaacttttcc
    30301 atactagggt cgtaaaaagt catagttcca attccagata ttttatctct tacccataat
    30361 ccaagtttat acttgccatt ttctttttta gtctctatta cttctgtttt atacttattt
    30421 tttctctcaa aagtcacttc aactttactt tttttaatct tattcaaaat ctctgataca
    30481 tcttgactat tttttatcct tttattatct atttttacta tattatcacc gatttgtatg
    30541 cctccaatat agtctacatc ctcttcctca tatcctaaga ccaatacacc atctgtattt
    30601 gcttttactc caattatatt tcccatagga tatacaaatt ttttatcatg attcttaatt
    30661 gtaaaagctt ctatttgagt ctctttatta acattacaat ttttattaaa aattataacc
    30721 atggtaaaaa tcgatacagc tcctaatatt atccaaatat ttttgaaatt tttatttatt
    30781 ttgttcatat atccatctac tcctatgctg tattattatg tatttataat tcctttttcc
    30841 tgagaattta ttcatttaaa aagtttattt aaaatcttaa taagtgattt ttaatacata
    30901 atatgatagt attagattgt aacaaaaagt ttgaagggcg gtaatatctt gaaattaaat
    30961 gtaagaattg cagacataaa taattggcat gatttagtta gtttgtctgt agataaaagt
    31021 cagttagatt atatagaaag caatgcactt tctattgctg aatctaaatt tataacagct
    31081 tgggtacctg ttggaatata tgatgaaaat tctttaatag gatttgctat gtatggtcgt
    31141 ttagaagatg atagagtttg gcttgataga tttatgattg attcaaaata tcaaggtaaa
    31201 ggatatggaa aagcatcatt agattttctt gtaaatcatc ttaaaaatga atataactgt
    31261 gatgaactat atcttagtat attcgaagac aataaaatgg ctattaagct ttataaagat
    31321 tttggatttg agtttaatgg agagcttgac tatggtggtg aaaaagtaat ggtattaaaa
    31381 tctaattgat attaagaaaa atatacatat atcaaggagg tgaagtcatt atataaacat
    31441 gtttatataa tggcggataa aatggctcaa aatataactt tacaatttgt tgaagaaaaa
    31501 gatttagaaa accttgaaaa cgtaaaactt ctatttactg aatattcaaa ttctctaaat
    31561 atagacttat gttttcaaga ctttaataat gaattaaaaa cacttccagg aaaatataaa
    31621 aaaccttcag gctcattgat attagcattt gttgatgaaa atttggcagg ttgtgttgct
    31681 ttaaaaaaac ttgaaggtaa aatatgtgaa ttaaaaagat tatatgtaag aaatcaattt
    31741 agaggattaa aaataggaaa aatactattg gaagaaatca ttgaagaagc taaaaaattt
    31801 ggatatacac acatgagatt agatactctt ccaagcatga aaagtgcaca aggattatat
    31861 gaaaagtttg gtttttatga tatagaacct tatacttata atccaattga aggggctaga
    31921 tatatggaat taaaattata attttttaat agagtataag taaaactact acagttttat
    31981 ttatactcta ttttattgaa caaatctatt tgaatattta tttaaatatg tatttatttt
    32041 tctaaatctt gtaatcccat agttatatct tcagttatat cctttgtata ttctactcca
    32101 ttattgtatg taagtttagc tttaatataa attatgccat caatatccct tttaggaaaa
    32161 cttacttcat aattcacttg atttctattt gaattattag ttttgccatc atctaagcct
    32221 tcagctaatt tggctttgta tatagtgtct ttttttcctt catttacaat aatatctact
    32281 ttttctaatc taatattatc ataaacttta ttttttgact tttcactctc atgattgaaa
    32341 agattactat tttctactat ttcaataaag tattctctat tatctcttat cccagaatta
    32401 aatatgggtt gttcaggcat ataatcagat ttagtcaatt tttgcacatc agaactttca
    32461 gatatagctc cacttgtaac tactttatag tcatattcac ttcctgtatt tatctttatt
    32521 tcacatgcat atgataattc tccatgtttt gtcatctcag tttcattcca tttatcacta
    32581 tcttctttat acataaaaaa tacttttcca ttttttccaa gtttacttaa ttgaacatct
    32641 acatcaataa cacactcttt tttctcgatt ttttttactt ttaagtcaat actctttgtt
    32701 atataacttt ttgacatttc ttcatttata gtattactaa tatccgattt agtactcata
    32761 atctcttgtg acaaataatc taatttatta ctacaacttt caatattttt attaatctca
    32821 cttaccgtta ccacaatata ccataataaa ataaaaatta caattgtaaa aattaagtgc
    32881 atagtatctt ttttattcat tttatgtccc cctcactact accttaataa ataatattat
    32941 acttaagcat ttagaaattt caaagttaca aatttataca aattttcttc tatttttaaa
    33001 tctacttttc ttcaatatag gcactagata ttttaaaata atttcatcat aaaaaataga
    33061 tgtaaagcat ttctataaaa attctttaca cctattaaaa tgcttgtttt tcactaacat
    33121 tttttagcca actcaataat ttcacttgca tgttcaatag ttttttctgt tatattgtta
    33181 cctgctataa gtctggcaat ttcatttttt cgttgagatt catttaactt actaacattg
    33241 gtaaacgtcc tattatttga agtatctttc tctatacaat aatgagtgtc tgcatttgca
    33301 gcaatttgag gtaaatgagt tatacatatt atctgttttt tctttgctat atcactcaat
    33361 ttctcaccaa ctatctgtgc tgctatccca cttattccag tatctatctc gtcaaacact
    33421 aatgtatcaa tatcatctat atcagccaat atggttttaa acgctaacat aaatctggac
    33481 atctcaccac ctgatgcaac tttatatata ggcttaatat cttctcctaa gttaaaagat
    33541 atcataaatt caatatcatc tactccatct aaagtaaatg gacctttttc aaaattaacc
    33601 ttgaacatta catttttcat atttaagctt tttaattcat caagaagtat tttttctaaa
    33661 gtagttgcta cttctattct tgctttagtc aatttactgg cttttatttt taaatcttct
    33721 tctatattca tcagtttgct tcttaactgt tcaactcttt catctctgtt taatatttca
    33781 tctaatctat ctttaatttt tccataatac tcaaatatat catctatact gtctccatat
    33841 tttcttctta agttattaat ctcgtcgatt ctaagctcaa tctgctctag ctcataaggt
    33901 tcaaagtcta tattatcttt gtaatttctt atctcaccag atatgtcttg taactcatac
    33961 atgattcttt ctacagtatc actatattca cttaaaacac tgtcatattt agatatgtca
    34021 ttaagttcct tagatgcaag acctattagg tcaataacat tatactcacc attatgtaac
    34081 ttgctataac tcgaatttag attattatat atcttttcac tatttctata aacttctctt
    34141 tgttttaata aatcttcata ttcattctta tttagatttg cagcttcaat ttcatttatt
    34201 tgaaatctta ataaatctat ttctcgttga atttgcatct catctttatt ttctgtcaag
    34261 caatttaaag ctttttttac ttcactatac ttatggtaca catttttata agcaatttta
    34321 aactcttcca attcattttc tccaaaaagg tctagaaatt ttaaatgagt atctttatta
    34381 aacaaagctt gattttgatg ttgaccatgt atatctataa gtgtagatgc aatttcttta
    34441 agaagagaca ctttaacagt ccttccattt actctagcag tactcttacc atctgagtat
    34501 atcaacctag ttattaccaa taaattatca tcttccatac ttatatcatt ttcttctaat
    34561 atttttttaa gatatctatt gtctgaaaaa aatacagcct caacaagtcc cttatctgtt
    34621 ccttttctta aaaaagacct atcatattta tcacctaaac aaagtccaag tgcatctatt
    34681 attatagatt ttcctgaacc agtttcacct gtaagtatat ttaggttttt atcaatattc
    34741 aaccttagtt cttcaactaa ggcacaattt ttcatatata attcgaggat caaatctaag
    34801 ccccctttta acctatttgt ctaaattatg agaagcttca acaacttcta ctattttgtt
    34861 attgtatgtc tcaccatcaa attcatatcc ttcatttcca tttctcaaat gaattagata
    34921 ttctatatta ccttcaggac ctttaatagg agaaaaatct aaccctaaaa tctcaaatcc
    34981 attttcgact gagaaatcag aaatcatttt tataacttct atatgtgtag atttttctct
    35041 aactactcct tttttaccta ctttttctct tcctgcttca aattgaggtt taattaaagc
    35101 gacaacttcc ccatcatgac gtactaactc ctttgccttt ggaagtacta actttaacga
    35161 tataaaagac acatcaattg acgcaaaatc agcaaactgc tttgtatctt ctattgtcac
    35221 atttcttata ttggttcttt ccatacacac aaccctatca tcttgtctca atttccatgc
    35281 aagttgacca taaccaacat ctatagaaaa tacttttatt gctccatttt tgagcataca
    35341 atctgtaaaa ccacctgtgg atgcccctat atccatacat acctttccat caatagtcaa
    35401 atcaaagttt ttcattgctt tttcaagttt taaaccacct ctactgacat atggtattgg
    35461 atttcctttt acttctatac tacaatcttc ttttacttct gtaccagcct tatcacacct
    35521 ttgattatca acaaaaacca atccagccat tattgctttt ttggctcttt ctctactttc
    35581 aaagtaccct tgttctacta ataataaatc tattcttttt ttcatacaat tacctttctg
    35641 ttaaaaacta ctttaatgat aactaaagta gcttgaagta acacacttga tatttattct
    35701 aattgataaa ttctatattt tatataaatt ttaatttaca atatctacat tagattttta
    35761 ctcaataact aatttcctta tcttatcagc aatacttttt ggcgataatc ctacaaagtc
    35821 atataattca tctatattgc catgttttac aaattcttct ggtattgcta tattaagtat
    35881 atttacgtta tattcattat ctataataaa cttatttatt ctacttccaa atcctccagt
    35941 tacaatatta tcctctatag taactacatt tttatgattt tttaataatg cttttaacat
    36001 accttcatca attggcttta agaatctagc attaactatt gtcggattta ttccttctct
    36061 tgataatatt tctttagcct ctaaagcatg ttttaccata cttccaatac aaagtatgac
    36121 tgtatcttga ccctcatcta atacctcata tttacccagt acaatctctc catactctcc
    36181 cttatctagg taataactac ttcctcttgg gtatctaatt gctagtggac aatctaattt
    36241 taatgacaaa tccatcataa gctccatctc tcttgtgtct tttggagcca ttactacaat
    36301 atttggaata gaatttaagt aacttaaatc aaacatacca tgatgagttt ctccatcatt
    36361 tccaactaat ccagctctat ctataagaaa agtaactggc ttttttgtta tgcatacatc
    36421 atgaataact tggtcatatg ccctttgcaa aaatgatgag tacacagcaa agtaaggttt
    36481 cataccattt tttgcaagac ctgctgcaaa tcctgttgca tgttgttcag ctataccaac
    36541 atcataatat ctttttggat atgcactttc aaacaggttt agccctgtac cagatggcat
    36601 tgcagctgtt attgctacta tattttcatt actattagcc atatcaacaa gtttttctcc
    36661 aacactaatt gacatagact taacttttgc agatgtaaca cctgtcttta tatcaaactt
    36721 tgatactcca tgatatttat caggttgttc ttctgcaaat ctgtaccctt ttcctttttt
    36781 cgtaattaca tgtaaaagaa caggcccttt tttgtgttta gcttttctca atatatctat
    36841 tagttcttta gtattatggc catctatagg tccataatat cttataccta atgaatcaaa
    36901 aaatgaacag tcctgaggag aaaagctata cattagttta tctttaaatc tatgtgcagt
    36961 cttagataaa atttcacctg tttgtgtaac atttaaaatt ttatcaactt catctgtcat
    37021 tttctcaact gttgagtttc ttataatact tgacagatat ttagacattc ctccaacatt
    37081 tttatctatg gacatctcat tatcattaag gattactatc atattggtat ctatatatcc
    37141 taattgattt aaagcttcaa gtgccatacc tcctgttata gaaccatctc ctatcacaga
    37201 tatcacacta tagttttctt tttttatatc cctagcacag gcaatacctg tagctataga
    37261 aatagatgta ctgctatgtc ctgtatcaaa aatatcatga ggactttcat tctcctttgg
    37321 aaaaccactt agtccattaa actgtctcaa agatacaaaa caatcttttc ttccagtaac
    37381 tattttatga acataagatt gatgccctac atcccataca atcttatctt tagggctatc
    37441 aaatacttta tgaagtgcta atgttaactc aaccactcct agattagaag ctaagtgtcc
    37501 tcctgtcttt gaaacagatt ttactaagaa ctttcttata tcctttgcaa gtaaatccat
    37561 ttcttctata ctcatatttt ttatatcctt tggagaattt actttatcta aatatttata
    37621 catattatcc tcacctttat tctgtaaatt ttcaatttac atcaatatta aagctgttac
    37681 tattccaagt aaagctccaa accaaacttc tagtggtgta tgacctatta attcttttaa
    37741 tttcttctgc tctatatgct ttccatgctg tatatctgcc accatttgat ttaatatagt
    37801 agcttgttta ccaacagccc gtctaacacc tgctgcatca tacattataa ttaaggcaag
    37861 cacggtaatt atagcaaaat cagtagaatt aaaccctttt tcaataccta ccactgtagc
    37921 taaacttgta acaaaagaac tatgggaact aggcatacct cctgaaataa gtattcttga
    37981 taactcaatt cttttttcct taccagtaaa tatttttata aattgtgcta agaaacaagc
    38041 aatcagactt attcccaaag ccccattgtt aaaaatctcc gaaaaaaaat ccatttttcc
    38101 ctcctcgatt ttagctgtat attttagtat tctctatcta ttatatattc agccaatccc
    38161 tttaaaaaat ctacatcatc agataatttt tctatacttt tctttgcttc atcaatcaaa
    38221 ttatgtgcaa tttctttaga tttatctaaa cctaaaagag atgggtatgt tgacttatga
    38281 ttttctatat cacttccaac ctttttacct aacttagctt catctcctac tatgtctagt
    38341 atatcatcta ctatctggaa tgataatccg atattttttg catatttagt tatttcttcc
    38401 atttgttcag aatttgctcc acctatagta gctcctgctc tcatacagcc taccatcatt
    38461 gcagcagttt tattcatatg tatataatct aatttttctt tttcaatttg tttattttcg
    38521 ctttctacat ctactacttg accacctatc attccatata taccagcacc tttggcaatt
    38581 tcatttatag cttttagata cttttctgga ttttctttat tgattgagcc tgcaagcatt
    38641 acttcaaaag catagtttaa caaagcatct cctgctaaaa tccccatagc ttctccatat
    38701 actttatgat ttgttggtct tcctcttctt aaatcatcat tgtcaagagc tggcaaatca
    38761 tcatgtatta gtgaatatgt atgtatcatt tcaattgcaa tagcaaaagg aatagcttca
    38821 tcttcattac ctccaactat tttacaagcc tccaatgtaa gtattggtct taatctttta
    38881 cctccagcac ttaagctata gttcatagct tcaataacag ttttttgata cccttcttct
    38941 ttaggcatat attctttaag tactttttct acaaaacttg ctttttcttt tagacattgt
    39001 ttaaattcca attttattcc tcctctattt taaagtcttc ttctattccc aattgattaa
    39061 atttacttat tttcaattta gcatcatcta aaagcttatt acaatgttta taaaggctta
    39121 taccttcttc atataggctt aaagattcat ccaagctagc atttttagat tctaattcac
    39181 ttaaaatact ttctaatctt ttataagctt cttcgtaggt taaattcata ctatccctct
    39241 ttattttcaa ttttatctat catacattct aaatttccat cttttaatac tatatctata
    39301 ctatccttta tttttaatcc ttttatacta tttattactt ttccattttt ttgagttata
    39361 ctataacctc tatccatagt agctaatgga cttaaattat ggagtaatgc tccaattttt
    39421 actaattttt catcttctaa ttttaaatta ttttctattc caaaaattat tttatcatat
    39481 attttgtcta attgtataac tttatctttt attgtgtacg aatctaaata gttatttatc
    39541 ttattaaata ctgtttctaa cctatattgg tctagctcta tttgatttgt aagagactta
    39601 ctcatcctac tttttatgtt tccaagttta tagtttatat catccaatga tggagtagca
    39661 atctcagctg ctgctgatgg cgttggggct ctcatatcag acacaaagtc acaaatagta
    39721 aaatccgttt catgcccaac tgctgatatt atcggaattt gagaattaaa aacctctctt
    39781 gctaccattt catcattaaa agaccaaagt tcttctatcg aacccccacc tctaccaact
    39841 ataagtgtat caacattctt catatgattg aaaaatctaa ttgcttcaca gatttcttca
    39901 gctgatttat ctccttgaac cgttactgga taaagcttta tattaacttt cggatatctt
    39961 ctttttatta catttattat atctcttata acagcacctg ttggagatgt tataacgcca
    40021 attgagtttg gcattttagg tataggtatc ttgtatttag ggtcaaataa tccttcttta
    40081 ttaagttttt cctttaatct attaaactct atgtgtaaat ttcctattcc ctctatttca
    40141 atttcattaa tgtataattg atacgcacca tctctttcat agactgatat atatccatta
    40201 gctataattt ttacaccatt atctaatttt aaattgcgat taaaattact tttaaaaatt
    40261 acacagttta actttgatgt ttcatcttta agtgataaat atacattccc actactatga
    40321 accttaaaat tagaaatttc tcctttaact ttaagattag aaagtattgg gtcgtttatt
    40381 aaaattcttt taatatatga gtttgcttca cttatatcta aagctcttag tttcatactc
    40441 tttctcctaa aaagttattc aatcctatta tagcacaccc gacagcatta tcagttgaat
    40501 attgtggttc tgtaaaataa gcttctatat gcttttttct taacttcacg cttaattctc
    40561 taagaatata cttacttgca gaaactccac cagcaaatac tacttcattt acattataag
    40621 tttcacataa atacactaaa gatttaaaca tatttctaac tactgaatct aataccaatt
    40681 tagatatata ttctttttga ttagtattat atccattatc atttataatc ttatttacct
    40741 gattttctaa tcctgataaa ttcatatacc catctcttac agaagttttc agaccacttt
    40801 ctattttaag attacaattt aaagcatttt catccaaata ctttcctgaa ggaaatttat
    40861 atccaagctt aattcctact ctatctataa gttgaccaaa gctaatatct ttacttcctc
    40921 caattatatc tatattatat ccaaaattat tgtataactt acttttatca tcttttttaa
    40981 tacttatttt ggcaatttta cctaaattag tatcacatac attgtgatga ctatcttgtt
    41041 tgcttgttaa aagtatctct gtagtaccac cagacatatg aacagaaata aatttattat
    41101 tattttttaa tttactattt aataaacttg cttcaatatg attctcttga tgagtagtct
    41161 cataaaacct acaaccatat atactagaca ataattttcc aaaattatga cctacattga
    41221 atacaggcat atatgagttt tcaacaggtc tcggtttttt tgatgagcaa actccttcta
    41281 cattaaactt atctttaaaa gattttatcc tatcactaag aatccctaaa ttattgatat
    41341 gttgaaatac agcttcactt tgccttaaac cttttgaatt atcccttact tctaacatta
    41401 ttttttcatt gaatataact ttcttatcta aagagatagc tgctatagaa gtagtatagc
    41461 agctagtatc aattccaatt attatattat ttcccaattt catcaacaac acttcccaat
    41521 ataccattta taaatttagg agacttatca tcacaatata tttttgcaag ttctactgct
    41581 tcatttattg atactttatt aggagtgtct aaataaagta tttcacacac agacaatcta
    41641 agtatagaaa catctacctt tggcattcta tctactgtcc agtttttagc atgcttattt
    41701 attaactcat ctattttgtc atgattttct ttcaatgctt tgcatactgt atttatatat
    41761 tttttgtcta taacatcttc aatttcagta tcttctaact ttaaatttgt attttttgag
    41821 tattgaagtg caagttcttt atatctattt ataatatgtt ctgaattatc ttttaaaaaa
    41881 ttatctactt tatcttctaa agtttcaaaa tcttctttat taatatttat ttggtatata
    41941 agtttcatta tatattctct tgttgtactc ttttgtgccc tatctttttt catcaatcaa
    42001 aattctcctt taagtttaat tatccatata aaatcaatta ccagcaaaaa accctctgac
    42061 ttttcagagg gctaatatta atttttctta gttgcttttg cttcttcttt atcaacttta
    42121 tccttcttaa agctgattcc ttgaatgtgt atatttactt gagaaacctt cagtcctgtc
    42181 attgtctcaa cagtattttt tacattttct tgaactttaa aagctgtatc tggtattgac
    42241 attccatact ttatcgtaac cattacatct aaattaacat cctcttcttc gatttgtatt
    42301 tttactccat tattttttaa caacttatct gttaatgttg ctgtagtttc tatgccttca
    42361 acttctaatg ctgctaaacc agctattgta gctattacat cattagatat ttttacttgt
    42421 ccaaatttat tatcttccat attaaaactt acctcctgat tttaaggaac tatttttata
    42481 agtataataa taccaaatac aagtctactt tgcaagaaaa taacctcagt taattctgag
    42541 gtttatactt tacttattac tattattatt tgtaagttta atattttcat acttcacatt
    42601 ggcttgttct gcaactaaat caaatatttt tgctgcatct ttcttttcta atttagcttc
    42661 atttacaact acattaactt tgttatcgct tatataaact aacgcttctt catacccttt
    42721 tgtactcaaa aggttttcta tttgaagttc tttttcttga attttaacta tatttaattt
    42781 catattagaa gcttcttttc tagattcttc tgttgtagat ggattattta tcatttcatt
    42841 taaatcttga actaactcat ttctttgttt ttctctattc attttcatat ctaaaatata
    42901 agatgccttt ttcatatttt tctctgatga taattgagct tttatttcct tacttgtctc
    42961 agttgccttt tcttttactt tactagcttt gctatcaact atatcaatat cagcactttc
    43021 cttaccatct tgtttatcta tattactaga atcctctgtc ttactactat cactctcatc
    43081 attatttttt tgcaactgtg cttcttcata tgccttaaac tcttttgatg tttctaataa
    43141 agatttctta cttagttgat aattcactgt tcctactacc actaacattg cagttaaagt
    43201 tattattaca aatcctcttc ccttataatt aaacttcatt catttatccc cccggttata
    43261 tgtatttatt tagaatatat ttctacttga tgaccagcta cttgtaatga tgtttgtact
    43321 gcactataaa gtgtctcttt aacacttggg tcacttgctc cacttgctac cactatcact
    43381 ccctttatct ttggctctgt agtttttata actacagggt cacttgaatt tgaagttatc
    43441 attgttttat tttcactaga agtcgtaact gttctttctc caccttgtgc atctttttcc
    43501 tctgttgttt ctgttgtatt atttgaatta aaagcaggtt gtatttcttc acttgattca
    43561 aatgtaacca ttacatcaac gtctcctgca ccatcaattt tagatagtat tgctgttaat
    43621 tttgactcta aatcatcttt ttcttgttct ttagtgactt gcttttcagc atttttatta
    43681 gtctctgttt ttccaacttg tttatcgctt ttgctactag gaaaacaaga taataatact
    43741 aatgaaacca cacatattcc tgctatagtt attagtgaat atacctttct cttatctttg
    43801 tcatttaagt ttttcaacat tctcccaact cctatttatc aatttgtata tcttctatag
    43861 aaacatccag cacctttatt aagtcgtttt ttaatttttc ttcatttagg ttcaacccat
    43921 actctgtacc ttttttgaag acttgtttag aattttcttt gtcattagag tttatgtttt
    43981 cttcctctct tttagtacta ttatttttat tttcttcatt ggaactgtta ttactttttg
    44041 cactattatt cttttctttt atttttatat tatttatatt tgccccatta agctctatat
    44101 cttctaaatc ataaccatat tcatcaagtt ttaatttaag tacttctttt aacccatcct
    44161 catatccctt ggatagacta ttatttccag tctcttttgc caaagcattt gtactatcta
    44221 catactgctt gttgtagttt cccatagatt ttaatattct atcttctaaa ctcatatctt
    44281 ttgaaaaaaa tcctactact ggagttatta caataaatac aaacataaag tttaaaacta
    44341 ggttgacata aggttttatc ttagaacttg gtaaaatcat atctactata tttactataa
    44401 atgctcctat caaaacacta actatccatg cctttatgcc ctctaacata gcatcctcct
    44461 ctctaaaaac attagattaa atgtaattat ttttcactga tatataaatt acccttgact
    44521 tacgacactt atcgaggtca agatagctac agttacaaag aacattactg ttatagcaat
    44581 tactgatgct agcattatta tcattaaatt tgccacttca tttaaaaaat tagatattcc
    44641 atcctctcca acaggctcta caattattgc tgctaatttg tacactacta ttactgataa
    44701 aatttttatt actggaagta agcaaattcc aacaagtaag ataagcccta ttcctccaaa
    44761 tatatttttt ataagctgag atgaagataa taaaatatcc acagagtcag atacaaatcc
    44821 acctacaaca ggaataaaat tacctatagc aaatttagca gtctttacac tgaatttatc
    44881 aaaactggtt acatacagtc cttgtatgga tacaagacct aagtaaacag taaacatagc
    44941 tccaatagaa acataattta tttgttttac aaaggagaaa aatctcttta gccttatatt
    45001 ttttgataaa ttgtttatta ttaaaattcc aaatgcaaca gtaatagata caaatagaaa
    45061 atttttaaaa aatacattta taaatgttac tcctcctatg aagataggat tcaaagtagt
    45121 cgacgttatt gggaatccaa ttaaaagtaa aaatgttatt aatattggca ttataacttg
    45181 cataagacct acagtatggt ctattgcatc atagcaaatc tgtaatacat ctttaaaacc
    45241 aataagtgta agtgatacca ttgtgataaa tattatatat gttgctattt gacttactgc
    45301 acctgatgaa aaagagtttt ccagactctt taaaatagat gataacagag ccagtaccaa
    45361 aattactgct actaccttta aacttgcttt aaattcatca aacatcaata tcttcaatcc
    45421 atctttattg aataaatcta agatattttt ttctccacta attaaatctt ttacaaatga
    45481 ttttaaatta acatcattaa taactatttc tttatttata tagtcttgaa tctcatttat
    45541 atctagcttg tctaattgac catctatata cttatctatg ctattttttg tttcaccata
    45601 ttctttatct tcactacttg gtacttcatt agcaaatatc ataatagcaa agatatttac
    45661 aaaaaagaaa gtaaataaaa aacctataat cattggtaaa aatctttttt tcataagcaa
    45721 ccatgcctct cttcactcta taaacctcaa tacaacgaaa gctctctaat atacttatat
    45781 tcattccaag atacacatct atggaattat attcaccacc atttctacaa tggacaaaag
    45841 tatagggaaa gacattgaca taactattat tttacctcca aattctagtt ttgaagcaat
    45901 gtttccttcc ccacaatctt tacaaagttg tatcgcaaat tccattaagt atgctatccc
    45961 aattaatttt attattaatg atatatacat agtcgggatg ttagccttgt tagccaaatc
    46021 ttgtatacta tctactataa aatttagctt aaacataact gacaatagta ttattactcc
    46081 agttattata gctatgaaat ttgctatctc tggtctatct tttttaatta ctaaacagag
    46141 tgtagttgaa atgattgcaa ttcctattaa ttgcattatt tccaaattac tccctcctct
    46201 ttagtaaagt tgaaacattg ttcttacagt attaaacaag tcacttattt ctgttattac
    46261 catacccaat acgattatta cacctgctaa tgtagtaaga cctgcccaat cttttctatc
    46321 tgttttttcc aatatcatat tcaatactga tattagaata ccgacacctg caacctttaa
    46381 tatcaatgat atttccataa taaacctccc catattaaat caatataata catataccta
    46441 tacctatgaa tgtcactaat tttttataca atacgccttt tttgtttata tcttcctttg
    46501 tctcataggt ttgttttttc aaattttcta tagataaatc tatcattctt tgttgtgact
    46561 ctatatcgct tttccctaaa gtaagtatta gatttttcag ttcctcaatt tctttattgc
    46621 ctagataagt ttctttactt aagacatcaa tattttctga tattattatt tccaaagttt
    46681 tactttgttc attgtgaagt ccttctgata tttgatagaa aaatttccaa aaacaaaact
    46741 ctttatttcc acctatccta ttaaagattt cttctaatgt ataaagtcca aaagataaat
    46801 ccatcctcaa aatttctaaa actcttatta aatcgtttaa ttgtttatgt ctacgagtat
    46861 aagttttgta tatttgttca cctatcaaat aactacttcc tatcaagaaa gctataataa
    46921 ttattttaat ttgcaaaata ccatctcttt tcttctaaat cataaatttt ttcaattgtt
    46981 cctgctcctc tttttgcaga aagaattata acctttttaa ataactcttt atccagaagt
    47041 ctatttaatt cttttctatt ttgtatatcc tctattgaat ctccatgcac agtagttatt
    47101 aatcctatac ctccatttaa tgctgtgtat aatgccttta tttctttttc acttccaatt
    47161 tcatctgtca caataacatt tggtgacata gaccttaaaa gcattgtaat acccaagtct
    47221 tttgggcaag tttctattat atcagtcctt attcccacat ccatttgtgg aacacctaga
    47281 taagctcctg ctatctcatt acgctcatct actaaagcca cttttaaacc tttaaatcca
    47341 taatcttcat taccattact taaatttctt actatatctc ttattaaagt tgtttttcca
    47401 cattgaggtg gtgatattat caaagtatta ttaatctgat tttttccctt tatgatatga
    47461 cttaaaatct tatccgagca tccaataatt tcccttgata cccttatatt taaagatgat
    47521 atatgcttta tatttttgac ttgtccatct tctactattg cttttccaac taaccctact
    47581 ctatgacctc ctctcaaagt tatgaatcct ttttttatgt catccataaa tgaatgtatt
    47641 gaatatttac atattatttg aaaagtttgc tctacatctt ctcttgttac tacatatgag
    47701 ttttgttgat ttaaatcaag tgtcatagtt ttttgattgt aaaaataatc tttagagttt
    47761 gcatttagta tcaatggttt ttgtgagcgt aacctaattt cttctatgtt cagattattg
    47821 tttgagactt tttctacctt ttctcttata gttgtagaaa gagagtttat tatttcatca
    47881 gaaagtttat tcatctcttg tcctcctcct ttgtttatat aattctattt ataaaggaca
    47941 aggaatataa ccaaaacatc tatatttttt taataatgtt tataaataaa aaaagtgaac
    48001 ccatttatct tggattcact tagtaagtat aatataaact actattatta atctttataa
    48061 tatatttaat aagtattaac aaaaagacac ttcaatcatg aagtgcctct ataacatcta
    48121 catttctttt attagccctt tcttataagc cattaaaagt agttttaaat cttctatttc
    48181 ctcttgtatc tttattcctt catcagtatc tctcaccatt tttctctttg ccttatgctc
    48241 tactacaaca gttgtcgata agatatcact ttcatttgca atggcttctt cagcagaatt
    48301 aaatggttca tgcgatacta attgcaaagt tctagaattg tatatcaaag tgtatccagc
    48361 tataccagta gttttttggt aagccctaga aaaaccacca tctataacga gaattttacc
    48421 attagctttt attgggctct ctccattttt actctccaca ggaacatgac catttattat
    48481 atgagattca tcaagttcta aatcaaattc ttcaaataat cttttacaag ccatctcatt
    48541 ttctctaagt ttaaaatatg ggttcttatt ttctttatga gtctcttttt cagctataaa
    48601 gtatctttca aatgtagtca tatcatcttt accaaataat gatgaacatt tcccagtcca
    48661 taaataccac ataatatcca tgccatacag tttttcttct gccttatctt taaagaaaaa
    48721 tccttctctt gctagagact ccatcttatc cataagagcc ttacctttat actcttttcc
    48781 cattatattc atagacataa agcttccatc ttcatttaac ggtacacatc catgaatcag
    48841 taaatttgag ttagccttta aatatatact tcctttagaa aacaaaaatg aaacatgttt
    48901 ttgtagtttt tcactacctc taaatgaaga tactaattta tcaataacat ttctttcttc
    48961 catagttaat ttatatgggt cttttttgtc tattgtaggt aaataagtat cttttaattt
    49021 atatgtttta ccttttaaat taatcgtacc ttcatcatag tttatcatat taagcaagag
    49081 tctatgttcc atttcaaatt caggtcttcg tctgataacc tcaccttcaa gcttaaattg
    49141 aattatactt attgctttgt gcatttttgc cattaaagac ttttctgttg ttgttacact
    49201 ttggtcatta acctttggaa taaattcttt acaagggtca tctttataca tttctatagc
    49261 aaaagtggct aaaggcaata gatttattcc atatatgtct tctacaatgt ctaaattcgc
    49321 atatctagct gatatcctca gtgcatttgc tatacaagtt ttttcacctg aggctgcacc
    49381 catccacaat atatcatgat ttccccattg aatatctaca caatgatgtt caataagctt
    49441 atcgacaatt atatctggtc ttggacctct atcataaata tctcctatta catgaagtct
    49501 atctacaacc aatttttgta taactgtaga aatagcaatt ataaactcct tagctattcc
    49561 tatgtcaact attgtttcaa ctatactttt ataatactct tctttatgtt cacttttaac
    49621 atgctcatgc aaaagttctt ctattatgta tttaaaattt tctggtaaca gttttctaac
    49681 tttagaccta gtatatttgc tagaagcata tttacaaagt tctataagtc tataaatatt
    49741 tattctataa aaatcatcta tattttcctc ttgcttaatt attaggtcta acttttgttc
    49801 aggataatat acaagagttg ctaacatttt tttttcgctg tctcttattg tatttgaaaa
    49861 caattcttct atttttctct ttattacacc agaaccattt tttaatacat gtacaaatgg
    49921 ttcatattca ccatgtacat ctgttataaa atgctctgtt ccctttggaa gatttaatat
    49981 agcctctaaa tttattattt ctgtacttgc ttttgatata cttggatatt gttttgataa
    50041 taactttaaa tacttaagct tgctgtttaa ataatcatct gatattttac acagattttt
    50101 cataattcgt cctccaaaat tatattaagt tatattcttt tttaattata ccatacttaa
    50161 tatacttttt tcgagataaa atgtacacta attatattcc caataaaagt gacattccta
    50221 ttaaatcagt ataaacacca ttataataac attctttctt tagtatgctt tctacttcaa
    50281 atccaacttt tttgtataat cctatagcat tataattttc ttcattagtg acaagagtta
    50341 tcttcttggt tattccattt gatttacacc attctataag gtctaacata agccttttac
    50401 ccaatccaat tccccaatat ttttctttta caacaattcc taatactcca acatgctttc
    50461 cttttgcttt ttgattagaa tcaatcgttg caatcccaac tatttcacca tctataaatg
    50521 caatcagttt aacagaatta tcagatgctt ttgctgattc tatagcattt tcttgttcct
    50581 ccaaagatat tttatattca tcctttccaa atgacagaaa atgagtttct ccacccactt
    50641 cattataaaa atctataatg ctttgagcat cttctcttac accttctcta ataagtacgt
    50701 ctacaccatt ttttaatgtt attgttggca taaatttacc tcctaataag ttttttgtct
    50761 ataaacataa tactattgtt cttctgttgt tacaatattt ttcatttatt gataacaata
    50821 taaggctata ttaaaataaa aaattaataa tattttaata tagccttgta gatacttatt
    50881 tgtatttaat tttctgccaa tgtctaattt taactcaata aattgttata acataattaa
    50941 actattttct ttaaattttc accatagact tttctattat aagacttcat tataaagtat
    51001 aatggtactc caattgccaa agctcctaat cccataatta attgatgcat agatgcttgg
    51061 aataacaacc atgttccaac acatacagca attagaggaa tcactgctcc aaaaggagtt
    51121 ttaaaagtac ctactaattc tggtcttttc tttctaaaca ctaatacgga taaagatgtt
    51181 ggtatgtatt gtatgaatct agcaactgca cttattgctg ctaattcagc aaaacttcca
    51241 gatagagcta ttggtatagt gattaacata gtagctatta tcgctacata tggtgtacct
    51301 tttttatctt ttcttgcaaa tattctcggt aacattttat catcagctaa agctacacaa
    51361 cttcttggat ttacaaaagc accacacata caaattccac caacagaaac caatgttcca
    51421 aaggtaacca atccagctcc catatttcca aagcatattc ttgcagcatc tgccactggt
    51481 gtagatgtac tagataacga atctcctagt ataccaacac atacaacttg atttaatata
    51541 tatattattg atgcaattac tattacactt ataattgcta ttggtatatt tttttgtgga
    51601 ttttccatat cttctgctgc aactgctata gattcaaatc ctgtaaatga ataaaacatt
    51661 aaaagtgctg ctgctccaaa ctctgttgct ccagctcctg gaggtaccat tgttgaagaa
    51721 gtaaaattaa ctccttttat aaaaaatata cctattccta taaatagtat taatggaatt
    51781 agtttaccta cagttataac attttgtaca atttttgata gagatacacc taataagttt
    51841 ataattgtaa gcccaactat catagctaca attataattt tttgtatatg tggttcacct
    51901 gctggagccc atactgctga taatgatgta ggaaaaccta ctattaaagc tccccaagaa
    51961 atacatccta ttacccattt cataagacct acttcaaaac cacaaaaatc tccaaaagct
    52021 tcttttgtat atacataggc agcaccattt ttattgaatt tacctgcaac ctcagcaaaa
    52081 caaaatgcca tagataaaac taacaacata tcaaatatat atacaaatat acttgctaca
    52141 ccaaatgatt tcattgcatc tcctggtaat agaaaaactc cagctcctac tactgcatta
    52201 atacctaaaa gtataatact tattaatccc attttgttct tttcgttcat gttcaatccc
    52261 cccaaggtat attataaatt cgaacaaata tttataaaat atttaaatag tttttccatt
    52321 ttatcacagt aatctaccat catttctgga tgccactgta ctcctactac aaaattttca
    52381 tcctctttct caatagcttc tattatacca tcttttgagt atgctatggc ttttaatcct
    52441 tttccaagct gattgacact ttgatgatga taactatttg taagtaattg ttttcctaaa
    52501 attccctcta aaatacttcc ttctttaaca tcaactttat gagtagctac atgtctttta
    52561 gaagattgtg tatgttttat ataacttcct tctataagat tattatcttg atataaagtt
    52621 cctcctaaac ttacatttaa aatttgtagt cccctacata cacctaatat aggcttttta
    52681 agttctaatg ctatacttat tgcaattaaa tcaaattcat ccacttctgg atatataaat
    52741 gtcgtttctt ctcttgtttc ttctccatac agttgaggat tgatatccca tcccccagat
    52801 attaagactc catcaaccat ttcaatctgt ttttttataa cttctttatc tgtatttaca
    52861 ggaattatta ctggactacc gccacctttt agcactgcat ttatataatc attatttaca
    52921 tatgaccttt caagacctgg aaacatacca ttttccatta ttattaaatt tcctaaaatc
    52981 cctattattg gtttcataat taaactccta actaatcgat tgttttatgt attactttat
    53041 attcatataa ttttccaatg ctagagacag ttggtctggg caagatgttg gctttgtttt
    53101 acactctatt ccttttaact tttgtattac atcttctata ttcatgcctt caactaatac
    53161 ttttagccct tttaaatttc catcacatcc acctataaag tttacatttg taactttatt
    53221 ttcttttact tcaaattcaa tttctgtagc acaagtccct gttgttttgt atttcatcat
    53281 taaacctccc aattattttg tcgtcttatc tctataatta gcaatatgta tgccaaaatc
    53341 tataattatt tttatttatt atttatctag tattttcaat agttttatta gttgtatttt
    53401 ttacttctaa ttctatgtac acttttctta caaataaaaa taggtaatgg gttattctaa
    53461 cttaacctat tacctatcta atcctatttt aaaaacctat taatatttaa ttataaatta
    53521 caatattctt tctgacataa tataaattaa tctctataaa tataaaagtt tattattatt
    53581 taaatatcta aattcaaaat atgtgatttc aatatcaaat acttagctta atttatatta
    53641 ttataaagtt ttatcccctc tgaggttatt tgacttcctc ctctaccaga tttagatgat
    53701 atgtatccac attcacttaa ataagatagc acctttctaa ctttgctttc agaaatctca
    53761 ataccttcct gtataagctt ttcgattata aaccctcttc caattccaga ggatgactct
    53821 cttctttcat atagaatcct cagtatttcc tcaaattctt ttcttgtata accaaatcca
    53881 tcttcataat tgttagcaca ttctaccctt atatatggtg gtaagtcatc tctaaaaacc
    53941 atactatcac acattagact tacataagaa gcaacatttt gtaactctct tatatttcct
    54001 ggccaattat atttttctaa aatagttata acttctggcg aaagtcttat attgtttttc
    54061 aaaaagaaat tcataagtgt tattatatct tcttttctat tcctcaatga tggtacatct
    54121 attggcaata catttagtct ataatacagg tcctctctaa attttccttc tctaatcatc
    54181 tttagtaagt ttttgtttgt tgctgctatg accctaacat ctatgtttat aacattatgg
    54241 gaacctatag gcataacctg cttttcttgt aataccctta gtaactttgt ctgtagcaat
    54301 ggaggcatat ctccaatttc atccagaaat atagttccat tattagcaag ttcaaataga
    54361 cccttttttc cttctcttaa agctcctgta aaagagcctt tttcatatcc aaacagttga
    54421 ctttctaata gactatctgg aactgctgca caattaactg ctataaacgg ttgattactt
    54481 ctattggaag cattatgaat tgattgtgat aataattctt taccagtacc actttctcct
    54541 attattaata cagaaaggtc tgatttagat atttttttag ccaattctac acactttacc
    54601 atatttttat ttttagtttt tatatcttta aatgtatatc ttgctatctg accttgttct
    54661 cttaatttat tagtaagatt ttgttctaat ttttttatat acgttatttc ttgtaagtta
    54721 taatatatcc cagctttatt ccccatagaa aaaatacttt ttttatttac atttatatat
    54781 tttttatttg taaataccac ttcatcaatt atttctttgt cttcaagtaa aatatttaaa
    54841 tcttcagaaa tgatatcttc tatgtttttg ccttgtggat tttcatttat acctaaaatt
    54901 tttaaagctt ctttattaaa tgtgtttatt ataccatctg ctgaagtaaa tattattcca
    54961 tcttttgata gattcaatat aacatcttgt tcttctattt ttaaaaacag ttgcctataa
    55021 ttatctttaa ctccattatc taaacttatt aaactctcag aatatgccat taaattttta
    55081 cgtatttctt taacatctat tctaagacca tttattattt ctataaaggt agatatatca
    55141 atatatctat ttccaaggtc gattacttta tttatataac ttggtacttt tccctttact
    55201 ccaggtgtta tagctatgtc tatattttta taaatttttc cttcaatata tggagtaaac
    55261 tttaaatttt ttactcctat tttgtaaaat aagcttatcg tttctaaggt agtttctttt
    55321 gtatcattta caaccaatac ttcagttcca tttggtattg aaaataatcc atatatttca
    55381 ttttctttaa gtgttctcct tatcactata atcttactat cttgtactaa atgctttctc
    55441 atactgttta atctatcatc attcattact agtacaaaat caccttgtat tttatcattc
    55501 tcttttaaaa cttccagata atagtggttt atatcaatat aattacctaa aaccaaacgt
    55561 atattttctt ctaagaaaga tgatagttta gttattttat cagttactat agctattgat
    55621 tgtttcatat ttatacctct tatttatata gtatataatt acttatatac tactttattt
    55681 ctaccaagtt gttttgcttt atataaattt ttatcagctt cttctagtac atctttgcta
    55741 tctgaaacat gagctacacc tgcacttata gtcacagtca catcatcatt ccacttttta
    55801 tttgcaattg caacccttat actgtcaatt atatctgcta cttcatcacc agatttattt
    55861 cttattaata cagaaaattc ttctcctccg tacctaaaga ctttatcatc ttgttctaac
    55921 ataacacaaa tggtatttgt tattcccttt ataacagtgt caccaaattt atgtccataa
    55981 ttatcattta tgagcttgaa attatcaata tctatcatca caagtgcaaa attatcatct
    56041 ttctctctgt acttttcata cataatatca aaactttttc tattataaac atttgtaaga
    56101 ccatcatgta aattttgtgc tttaaaatac ttcaatcggt tgtataaaaa agtagaccct
    56161 aatatagcaa ttaaaattac tgtaaataat attttataat attttatttc ttttttagtt
    56221 ttttcaaata gcttactttc gtttgatact ttatcaatta tatagaaact agtctctgaa
    56281 tctcttatac ttttgttctc tttatattca tttattaaca tcttttgata ctcatttaaa
    56341 gattctatat ttccttgttt ttcatatata tttaatatct tatttaaatt ttttattttc
    56401 tcctgggtta actttctttt agtagatatc tctaaacttt ttttataatt atctattgca
    56461 gaattataat tttcgctttt atattctaag tttcccattg ccatataata gtacatatct
    56521 ttatctaata tataaactgt tctatctgat tttataagat aatcagcttt ttctaaaaaa
    56581 gtctttgcct tttgtatatt atttttgccc acatacgcat ttgactgcat tatagaggcc
    56641 attatatcaa aatcattgta attatccgta tttacaaact ttttataatc ttttatcctg
    56701 ctacttattt caatagcttt atcatattcg ccctcttcta catatatttc tgctagattt
    56761 ataatagcat ataatctaac cattccattt ttttcacctt catcaatatc tattttaaaa
    56821 gaatccttta ttaatttctc tcctgtttca tagccaccta tctttaaaaa tatgctcgcc
    56881 aaatcaacat ctagtcttgc tttttcataa ttattcccca atttctcagc caactttata
    56941 gactttacag ttaaatctac tgccttagaa taattattat ccattatata cactgatgct
    57001 aatctttttt ctatattaaa tctacattca tcagataatt tcacatctga ttctctcatc
    57061 ttttctaaag aatcaatgac tatcttcgtt ccatctggaa catatgaaat agtctttaac
    57121 atatcccaaa cttcattata tactttattg tatttttttt ctggaataga ttcaaaagaa
    57181 gtcttaacca ctttttttgc ttcatcatac tccttatctg ccacaaggct ttcagacata
    57241 tattttccct tatttataat ttctctttct ttcaatccat tttggtcata ctttataaac
    57301 aaaataatac taataagtac tatacatata aaaattatct ttttgggtaa ccttttcttt
    57361 ggtagtctaa aattcaaaat tttagtcctc cttttgtata ttgtagaatg aaaacttgca
    57421 tatataaata acctcttaat aattaataat acaatatatc aaaatgattt acaacatatg
    57481 ctagacttaa atcttaataa aaaagtctcc taaaataatt taggagactt taaatttaag
    57541 ctaatataaa tttatacagt taaaacaagt gcttgttttt tagttttata tttaatattt
    57601 atttatacat atttttttag tactattgta gcattatgcc caccaaatcc taaagaattt
    57661 gatagtgcat atctaatatt tttttcttta ccttgatttg gaacataatc taaatctaaa
    57721 tcttcaccaa cttcttgtat gtttatagtt ggaggcacaa aactatcttc tatactcata
    57781 gcacaaacaa cagcctctat agcacctgat gctcctaata agtgaccagt catagatttt
    57841 gttgatgaca cacataagtc atatgccttt tctccaaata cagtttttat agccatagtt
    57901 tcatataaat cattgtaata agttgaagtt ccatgagcat ttatataatc tacttcttct
    57961 aatggaacat ttccatcttt caaagccata ttcatagacc tagctgctcc ctctccattt
    58021 tcagctggag ttgtcatatg gtatgcatca gcagttaaac catatccaac tacttctgca
    58081 tatattttag cgcctcttgc taaagcatgt tctaagtctt ctaagataac aatacctgct
    58141 ccttctccca ttacaaaacc atctctgtct ttatcaaatg gtcttgatgc agttttaggg
    58201 tcatcatttc tagttgacat agccttcatg ttacagaatc cagcaaaagc aagacctgtt
    58261 acagcagctt cagaaccccc tgctaccata atgtctgcat cacctctttg aattacctta
    58321 aaagcatcac ctattgaatg agttcctgat gcacaagctg tacatacatt agtgttaggc
    58381 ccttttgctc ctaaaaatat tgaaacttga ccagctgcca tatttcctat catcataggt
    58441 acaaaaagtg aacttactct tttatttcct ttttccaaaa gaattttatg ttgagtttct
    58501 atggcttcaa ctccacctat tccagaacct attataacac caaaacgttc tctatcaact
    58561 ttatctaaat caagatttgc atcttcaact gctaatttag cagatactat tgcaaattga
    58621 gcaaatttat ctaatctctt caattctttt ttacttatat attcttctgg atgaaaattc
    58681 ttaacttctc ctgctatctg agtttgatat gtgctagcat caaaattagt tattttatct
    58741 ataccagata ctccagattt tatattactc cagaactctt cttttcctgt tcccaacggt
    58801 gtaacacatc caagtcctgt tattactact cttttattca tcggatacct ccactttttt
    58861 aaagctcgac tatttattag cttctatata cttaactata tctcctatag atttgaagtt
    58921 ttctgcttct gtatctggta tttctatacc aaattcatct tcaagtgcca ttattatttc
    58981 tactgcatct aatgaatctg cttctaaatc cttcattaat gatgtctcca tagttatttc
    59041 tttatcttct actcctaatt gctctattat tatttctaca actttattaa acattgtgta
    59101 cctcctaaaa ttttttattt taatagattt ctctactttt taaattatta ttgcattacc
    59161 attccaccat ctacatttat tacttgtcct gttatataac ttgacatgtc actaactaaa
    59221 aatgctacgg cattggctac atcttctggt ttaccataag atttctttgg tatgtttgct
    59281 agtgttgatt cttttacatc atcacttagt actttagtca tatctgtttc tataaatcca
    59341 ggtgctactg catttatatt tatgtttctt gatgctaact ctcttgcaga agcttttgta
    59401 aatccaatta cacctgcttt tgatgcacaa taattagttt gccctgcatt acccataatt
    59461 ccaactactg aagtcatatt tattattctt ccatacttct ttttcatcat aggtttagta
    59521 actgcttttg tacaattaaa gacacctttt aagtttatat ctataactct atcaaaatct
    59581 tcttctttca ttctcataag cagaccatct ttagttatgc ctgcattatt aatcaatata
    59641 tcaatttttc caaattcgct tacaacagaa tctatcattt gattcacttc atcaaattta
    59701 gacacatcac attttataga ggtacacttt acccccatac tttctatttc atttttagtt
    59761 tttagtgctt catcttcttt agaagtataa ttgattacta catcagctcc aaaagatgct
    59821 agtttttttg ctatttcttt tcctataccc ctagagccac cagtaacaac tgctacttgt
    59881 cctgtaagat ttatcattat atctccccat ttctataatt ttgtacaaat tcattaagag
    59941 aatctatacc atctatatta taaatattga catttgcttt tttattggaa gctatcttct
    60001 taataaatgc ttttaaagtt tttccaggtc ccatttctat aaaagtatca tatccatcat
    60061 ttaaaagtct ttctatagaa tcttcccaaa gaacagatga acttacttgt tttataagca
    60121 ggtctttacc ttcgttttta tagtaatctg catttacatt tgccaccaca tcaactttag
    60181 gtttagttat gttaactttt tctaattcac tggccaattt tacaccagct tcttttaaca
    60241 ttgatgagtg aaaaggtcca cttacattta atttaactgc cctttttgct cctgcttctt
    60301 tgcattttac cattgcttct tctatctttt cattttcacc agatataact atttgtccag
    60361 gagaattgta atttgctact tctacaatac ctccttgtat atctttaacc acattttcaa
    60421 gtacatttct atctaaacct aaaattgctg ccatagctcc aacacctgct ggaactgttt
    60481 cctgcataaa cttacctctt tttttaacta aacatacagc atctttaaag tcaattgcat
    60541 ctgctgcaac caacgcacta tactctccta aggataatcc taagcatgca ttatatttta
    60601 aatctatttg agcttgtacc gcttttaata ctgctacact atgtgtaacc atagcaggtt
    60661 gagtgttttc agttttagaa agttcttctt catttccatt aaacataagg ttttttaaat
    60721 ccatatttaa gacatcacta gcctcatcta ttacactttt agcaacagta ttattttcat
    60781 ataaatcctt ggccatacct acatattgag ctccttgacc agggaatact agtgcaactt
    60841 ttcccatctt gctcctcctg atttacagtt ctattgctgg cataatctct cttgcttgat
    60901 ttaccatagc ctctataatt tccttacaag gtgttatttc ttttaccata gcagcacttt
    60961 gacctgccat aaatgaacct ttttctatgt ctccatctac tgttgcaaat cttaaagctc
    61021 ctgtaccttt tttatccagt tcttcaggag tagctccatt ttgttccatc tttaaaaatt
    61081 cttttgatag tttatttttt aatgttctta ctggatgacc agtacttctt cctgttacaa
    61141 ttgcatctct atcttttgct tttagtacta agtttttata gtttgaatgg acagaacact
    61201 cttcactgca aataaatcta gttcctactt gaactgcact ggcacctaat gcaaatgatg
    61261 ctgcaattcc tctaccatct acaattcctc cagcagctat tacaggtatg tttacagcat
    61321 cagcaacttg tggaactaag accatagtag taagttctcc tatatgtcct ccaccttcag
    61381 taccttctgc tattactgct gtagctccta gcttttccat tctttgtgcc aaagctattg
    61441 taggtactac aggaataacc tttgttccag cttcctttaa tctatccata tactttgcag
    61501 gatttccagc accagtagta ataacttgaa ctttttcttc tataatcaaa tcaattatat
    61561 catcaacaaa tggcgacata agcattacat ttactccaaa aggtttatct gttaattttt
    61621 tacactcaac aatttctttc tttatagctt cttttggtgc gtttcctgct gctattatgc
    61681 caagtcctcc tgcattagat acagcacttg ctaatgatgc agtagctacc catgccattc
    61741 ccccttggat aactgggtat tttatattta atattttgca aattttattc atacaattct
    61801 ccttcacttg aaatcataaa agtaaacttt ttattattaa tcaactttat tttgtgtata
    61861 agtttaattt tgttaattaa atcattttag atattttata ctataaagtc cacttgacaa
    61921 ctgaagcccc ccaagttaga cctccaccaa agccaactaa aactacatta tcaccctttt
    61981 taattttacc ttctctataa gcttcatcta atgctactgg tatagatgca gcagacatat
    62041 ttccatattt gtctatattt acataaactt ttttcatatc aagctctaat ctcttagaag
    62101 aagcttgtat gattcttata ttagcttgat gtggcactaa gtagtctata tcagttgtat
    62161 ttagatttgc tttttcaaga gctcttaaag aagtttctgc catctttcta actgcaaatt
    62221 taaacacatc actacctgcc atttctattg tatgtagatt agcttctaca gtctctttac
    62281 ttgccttaag tcttgaacct ccagcaggta cttttaaaca atcttttcct ttaccatcag
    62341 agcccatatg tgtagacagt attccaccct catttacagg gccaataaca gctgctccag
    62401 ctccatctcc aaacaatact gctgttgttc tatcatcata atttaaaaac ttagaacaag
    62461 tttctgctcc tattacaagc acatttttat agcaacctgt ttccacaaat tgctttgcaa
    62521 tagttactcc atatacaaat ccagaacaag ctgctgatat atcaaatgca gtagcattca
    62581 ctgctcctat tgcatcttgt actatacatg cagttgaagg caaagacata tcaggagtaa
    62641 ttgtagctaa tataatcagc tctatatcct ctacgtttaa ctttgcacat tctatagctt
    62701 ttaaggcagc tttagatgct aagtcagaag ttgcttcaga ctctttggca aatcttcttt
    62761 ccttaatacc agttctagta cttatccact catctgatgt atccattatt ttttcgaagt
    62821 gaaaattatc atatgattgc tcaggtaaat aacttcctac tcctaatatt ccagcctttg
    62881 tattcattat atattaaacc tccaaaacga gtttattcat cttcgttatt tttattttct
    62941 tcattgtatt tgcttataaa ttggttaata tcttcaacga cttttccctt tgaaaatttt
    63001 attccttgat ttatagcatt ttttatagct ttagcatcag aactaccatg agcttttata
    63061 actcctccat ttagacctaa aagtggagct cccccatact cagaataatc tataaaactt
    63121 tttaattttc ttaaatcatc ctttataagt aatgctccta ttttactttt tgtactggcc
    63181 ataaaagttt cctttataag actcataact gaaagtgcta caccttcagc agatttaagt
    63241 aatatattac ctgtaaatcc atcacatatg attatatctg tgtatgcatt tataacttct
    63301 ctagcttcta cattccctat aaaatttaaa tctaattttt taatttcttc atatgacctt
    63361 ttgactaaat cattgccttt gccttcttct agtccaacat ttgctaatgc taccttagga
    63421 ttttcaagac ctaaaacttt tcttgaataa atattactca tagctgcaaa ttcaactaga
    63481 ttcttaggtt tacaatctgc atttgcgcca cagtctgcta taagtgtcat tcctcgcttt
    63541 acatttggta ttgctgaaca taagcaaggt ctatcgattc cttttattct accaacaaca
    63601 aataatccac cagcaagtaa ggctcctgta tttccagctg atattatagc atctgccttt
    63661 ccttctttta caagatttaa tgctactacc atagatgaat cttttttact tcttatagcc
    63721 tttactggtt tatcttcgtt ttctataatc tcagtagtat gaactatctc taatttattt
    63781 ctatcaaatt cataatttga aaattccttt tcaagtaagt ctttatctcc tgtgattatt
    63841 aaatcaacct gatattcttt tatagcattt actgcgcctt ctacattaga tttaggtgca
    63901 ttatctccac ccattccatc aattactatt ttcataattt ccctcctaat ctaattcttc
    63961 aaagataaac tttcctctaa atatttgctc ttgggcttta ttgttgataa caacttttac
    64021 ataatgcttt ttatctatat ttctatacac ttctgctttt gctataagcc tatcttgttg
    64081 ttctatcaac ttaaaacttt ttacatttgc aactctcata ataaccttag gtgcatctat
    64141 tatagccatt gccaatgaat ctgctagaga aaaaatatac gtatctttta aagtattagt
    64201 cttagagtaa atcatgtcct gtgtaacttc taacatagat atacctaatc gccctacaga
    64261 taaatcaatg atttctcctg taatttcctt tactcctaaa gtctttactt ttgaactctg
    64321 agtttctgct attgatttga ctctttctct tagctctggt atgtttagac tcattctatc
    64381 taatcttatg gtctgtatac ttacatcaaa cagacttgat aattcttcat cagtataaaa
    64441 aggatctgtc tttagcatat ctataagctc tttttgtctt tgggctttac ttttcttttt
    64501 catgttccct ccaaatttta tagctgtaat tagtaccagc tactaatagt agtatatagt
    64561 aacacacaaa aattttcaat acttatatta ttatttttct attttttaat atgcataaaa
    64621 tccacttatt ttctctagta aatcatctta tttttttata tgtacaaaaa aaacatgtag
    64681 agtatactct acatgctttt tagaagctat tacttagaca caacttcttt acctttataa
    64741 tatccacagt ctggacacac tctatgtggt aattttggct catgacattg tgggcaactt
    64801 acaaatcctg ttgcttccat ctttgagtta gctgctcttc tcatttttgt gtttgattta
    64861 gacgttttac gctttggtac tgccatttac gccacctcct tagtcaaaat ttaattaaat
    64921 aaatctttta atttagcaaa acgaggatct atgtattcct catcgtttgt aatttcactg
    64981 caagaacact cttcttcatt taagtttgcc ccgcatactt gacaaagacc tttacagttt
    65041 tcactacaaa gaactttatg aggtacatta aaatctaatg tctgttctat tatatcaata
    65101 aggtcgattt cttcaccatc gaatataaaa ggatcaaatt cctcaaactc atcttcatca
    65161 taatcttctt cttttactaa aaaaccttgt atagaatact ctagtggtat ttctacttct
    65221 ttaagacatc ttgaacaatt gtcaacaatt gtaaaattga catctatatc tagatacaaa
    65281 cctttattag tctttgacac tttccctttt aaatttacag gtgatactaa tttgtaaatc
    65341 tcatcacaat aactaatagt atcaattttt tcacaaaaat tcaagtctat tttgtcagtt
    65401 tcttttctat ttattttttc tatgctaact ttcattaagt tcacctcaac atatcaccaa
    65461 atttattata caaatctagc atttgtttgt caagtatttt tacttgatag gcataggttt
    65521 aatttaatta ttttaccaat cttaatgtat ctctagctat cattaattct tcattagttg
    65581 gtattaaaag catttttact ttagaatcag cagtagatat tactgtttct tttcctctaa
    65641 catcattagc ttctttatct aatttcattc ctaaaaactc catgttagaa gcaatatctg
    65701 ctcttatagc ctttccattt tcaccaacgc ctgcagtaaa tactacaaca tccaatccat
    65761 tcatttcagc agcataagcg cctatatatt tttgtacttt tttaacatac gcttctaatg
    65821 tagcttgagc tctttcgtct ccatttttag ctgcatcttc tatatctctg aagtcactag
    65881 aaattccagt cattccatat actccagatt ctttattcat taatttatcc aatccatcag
    65941 catctaaacc ttcttttctc attaagaatg gtaatatagc tgggtctata tctccacatc
    66001 tagttcccat tattaatcct tctaatggag tgaatcccat agatgtatct acacattttc
    66061 caccatcaac agcagctata gaagcaccat ttcctaagtg acaagttact atttttaaat
    66121 cttttatatc ttttcctagt atctctgctg ctctctgaga tacataatta tgagaagttc
    66181 cgtggaatcc atatcttctt accccatatt tagtatatag ctcatgaggt aaaccatata
    66241 agtatgaaga tttaggcatt gtttgatgga aagcagtatc aaatacacct accattggta
    66301 catctggaag tatagcttta caagcatcta ttcccattat gtttgctgga ttatgaagtg
    66361 gagctaaatc tatacattct tttaaagctt cttctacttc tggagttatt actactgaag
    66421 ttgcaaattt ttctccagca tgtacaactc tatgtcctac tgcatctatt tctttcattt
    66481 ctttaactgc accaaattct ggatgagcaa cagcttctaa aactaatgct attgcatctt
    66541 tgtggtcctt cattggttgt tcaacaacgt atttatcatc tctacctgct ttttcatgtt
    66601 ttaatataga accttctatt cctattcttt caaccaatcc tatacataaa acttcttcat
    66661 tattcatatc tattaattga tattttaatg aagaactccc acagtttaat actaatattt
    66721 tcattattat ttcctcctta gattttttta taaataatat gtaataaatt ttgatttgta
    66781 ataaatgtct aaataaaact ctatctttta ttattttgtt atagatatat tattgtatac
    66841 attaaacgat tttcataaat aatatatcac cttttaatat aaaagtatat actttttttt
    66901 tatattatat catatttcta gtatggtaaa ttgtgtattt cactaataat atattaacaa
    66961 gttaacttaa tgtagattat tctttcccat ttgttataat aatataatat aaagagctaa
    67021 taaagttatt ttaataacat ttaaccagtt ttttatgtag gtaacatttc tacattttta
    67081 taaatttttt tacgtttttt aattttataa ttaaaaattt aaattttata catattataa
    67141 taaattgtga tatatataaa ataattaaag ataaaaggag tattttatga acatacttgg
    67201 attaatagtt gaatataacc catttcataa tggacacata tatcatttat ctaaatctat
    67261 agaaaaaaca aatgcaacac atactgtagc aataatgagt ggaaattttc tacaaagagg
    67321 cgaaccagct ttatttgata aatacactag agcaaaaatt gctgtcgaaa atggtgtaga
    67381 cttagttata gaattaccaa ctttatttgc ttgtcaaagt gctgaaattt tttctcatgg
    67441 tgctataaca attttaaatt cactaaactg cataaattct atatgttttg gtagtgaaga
    67501 aggaaataca gaaattcttt ataatatagc tgaaatttta gcaaatgaac caaatgaatt
    67561 taagttactt ttaaaaaaat atttagatga tggtctgtta tttccaacag ctagagctaa
    67621 tgcacttttt gattatatac atcaagacaa aaaaaataat tttatacaaa attattcaaa
    67681 ggaacaatta tcaaaaacat taaattcatc aaacaacata ctgggtatag aatacataaa
    67741 aaacctcatc catttaaaca gtagtataaa accatttact atctccaggg tccaatcaga
    67801 atataattcc gaagaaattg agagtgatat ttgttctgct actgctataa gaacttcact
    67861 taaagaaaat acagaccttt ttcatttaaa aaatgttatt ccagaaaaaa cttataacat
    67921 cctaaatgaa aaaatagata atggtttttt acctatgttt gatgacttct tctttgatat
    67981 tttaaaaaca attatactta gagatatgga cactttaaaa gagtattttg aggtaaatga
    68041 aggcatagaa aacagaatct ataaagatat ctttacatct gaatttctac atgaactaca
    68101 attagcaatt aaatccaagc gatacacttt aaccaaaatc aaacgaactc taaacaatat
    68161 attgctaggt attaaaaaaa gcgacatgca acttataaaa aacatagata ctatacctta
    68221 tataagaata cttgctttta atgataaagg tagagaaatt ctaaaagaga taaaaaataa
    68281 atctgaaata aaaataataa acaagttttc aaatatatca ttttcattag atgatacgat
    68341 ttttaaaaca ctcataagtt atgatataaa agctacaaat atatataatt caatatatta
    68401 taaaaacaat aaagatttag taaaaggccc tatggatttt tatactcatc caatatatgt
    68461 aaagtagttt tttaaaataa ctatatttat aaaaatcatt ttattaactc tttattatat
    68521 aagatacaat agtcttactt tatttatgta cacatgcttt taggatgaca acatcaactt
    68581 aaatattatg ttactttcta aatttaagta aatattgcca tcctaaaaat tttacaattt
    68641 agcttcagat ttaaaagtaa agtttaaaat attatattta aatctaattt aatatttttt
    68701 gttttgtaaa tattattaaa ttaatatttc taatatattt tccctggatt taaaatattt
    68761 ttagggtcaa aagctaactt tatattttta attaacatca tataagcatc tgaatttgat
    68821 tcatgtaagt actctttttt agcatatcct atgccatgtt caccagaaac ttgaccacta
    68881 agttctctag attttttata catatagtca aaagtttctt ttaatcttat tttccatgta
    68941 ttatcatcca taccatcttt taaaatatat atgtgtagat ttccatctcc tgcatgacca
    69001 aaacttttta ttcttatttt taatttgtct tgaagctcgt gagtgtatct tataaactct
    69061 gctatcttat ctcttggaac aacgacatca cattcatcca tttgtgtcgt agatgccttt
    69121 atagcttcta aaaatgcacc tctggctgac catatagaat cgtttctttc ttgtgtatct
    69181 gatataaata catctaatgc accattttct aaacataaat tagctacttt ttcatattct
    69241 ttttctatat cttcagtgct atttccatca aatgtaagta aaagataagc atctgatgta
    69301 ttatctggaa actttttacc taaaaattct tctgctgcca atattacatc tctttccata
    69361 aattctatag ccgttggtat tgattttgat tttattattt taggaacagt ttctattgcc
    69421 attgataaat ctggaaatgg tataagcaaa cttatacttt tctttggtaa aggaagcaat
    69481 tttaatatag ctttagtaac tattcctaaa gtaccttctg agcccactaa taaatccttt
    69541 atactatatc cagaactatt tttaactacc tttccaccta catttataat ttctccattt
    69601 ggtagtacaa cttcaagacc tcttacataa tcccttgtaa cgccatattt tactgctctc
    69661 ataccacctg cattagtgtt tatattgcct gcaattgtag cacttttttc acctgggtca
    69721 ggtgggtaaa ataaatctct atcttgaaca tattgaccta ttgtcatcaa taaaacacct
    69781 ggttctactg tcaatgttaa attttcataa tcaacttcaa gtattttatt cattttacat
    69841 agattaatca ttattccacc atttatggca acagcagcac ctacaagacc agtaccttga
    69901 cctcttggtg tgactggtat attattttta tatgcgtatt tcattatttt agatacttgt
    69961 tcagtttcaa gtacatttac taaaacttca gggtacttct caatccctcc aagttcatca
    70021 tgtgaaaaat cttcatttat atcacttcca actaatacat tttcttctcc acaagtatct
    70081 attaaaaaat ctatatcttt tttatcgatt aatttataca tttctatccc cctatttagc
    70141 tgctgatgcc atatattttt gattattatc tttgttattt tctatttttt caatcaattt
    70201 aggaataata tcataaatat cacctattaa agctaaatgt gctacatcaa gtataggcgc
    70261 tttatcatct ttatttattg ctactatata gtcagcaccc tgcatccctg caacaaattg
    70321 aacagctcca gatacaccac aagttattat caatttaggt tttacagttc taccactaag
    70381 acctatttgt tttttagcat ctatccaacc tgcttctatt acaggtcttg ttcctgccac
    70441 ttgagcgttt aacttatcag ctaatttata tatcatctcc atatcttctt gtttttttat
    70501 tgctctactt gccacaacta tcacttcagc ttcttccaga ccaacttctt tatttttttc
    70561 ttttacactc agtaccttaa ttttagattt tagttctttt ttttctactt tacataaagt
    70621 tatctttcct gtagtattct ctattttttc tggtgctgaa aatattttat atcttacagt
    70681 ggcaaattgt ggtctattat taggtgtgtt tatatgagcc attatatttc caccaaatgc
    70741 tggtcttatt tggtctaaat cagtatttga ttgaatatca agtattgtac aatctgctgt
    70801 aagacctgtt ctaaatctag cggcaagtct tggagctaat gacctaccta atgtagttcc
    70861 accaactaat actatcgttg gttttatttt atctataaag ttttctattg cttttgaata
    70921 tggttctatc ctaaaatctt taaattcatc ttcatcatat acaaatactt catccacccc
    70981 ataagaaatc aaattactgc acttatcttt tatgtctttt cctacaaata cacaatacac
    71041 aggttgtttt atttttgatg ccatctcacg agctttacct ataagctcgt acgttacagg
    71101 atgtatattt ccattatgat gttcaacata tactgcaatt cccctccatt catctttatt
    71161 aatttgtact ttactactct ctataaattc aaatgcgcct tttggtccac ttttgacaca
    71221 caacttgcac atcttacagc cagcacttat ttctactata cctgactttt cttctatagc
    71281 cccaaaagga catatttcta aaattctctt taagtcagtt attttatctt gatttacaac
    71341 tatctttgac atttattact cccccttaca ccaactttaa ttcctctaat ttatttacaa
    71401 gtgcaaaact tagttcatct gcatttcctc ttacaatatt tttatctgta tttggctttg
    71461 gaggaaatat tcttacaact tgagtaggag aaccattaag tccatagtta ttttcatttt
    71521 tatcttcaaa gtcatctaag ctatatacag gtatttctct atctttagta ttaagtttta
    71581 atttaaatga aggtagtctt ggttgaaaaa tgtctttttc tacagttatt aaacatggat
    71641 attcaatctc acatacttgt aaatcatttg gcatatctat ttcaacaact atactttcat
    71701 ctttaacttc aattaatttt gtaacgttag taacatgagg tatatctaaa aattcagcta
    71761 cttcaggtcc cacctgtgct gtatcaccat cagtagtttg ttttccacaa attattaggt
    71821 ctacctttcc catcttctta ataccttgtg atatggtata ggaagtagcc aatacatctg
    71881 ctcctccaaa tctcctatca cttattaatg ctccttcatc agctcccatc ataaaacttt
    71941 cttcaattac cttctttgcc tgaggaggac ccatgctaag tacttttaga ttcgctttct
    72001 tatcttcctt tattctaaga gctgtttcta aagcatatag gtcataggga ttcatttttg
    72061 aatctactcc atctcttttt agtactcctg tagtttcatc aacttctact gaagtcgttc
    72121 caggaacttg tttaatacat gtcaaaattt ccataaagta cactcctttt ttatttaact
    72181 ataactgata ctccatcagg tataactact actttgctct ccttaccaac tatactattc
    72241 gccatttcta aagcttcttt aaagttaaat gcatgtttca tatgcatttt ttttatcatt
    72301 tcaggattac acttatctgt taccattatc acagtatatt tagataatat tctcgctagt
    72361 atctgaaatt cccattggtc tggaatcgta tctactctat cgacacttct aattttatct
    72421 aaaagttgtt ttggagaatc tgcatttgct acattttcat aaaaagattg acctccatga
    72481 ccatcattac atgctgaaat cattattatt actccaccgt ctttacaagt agcttcagct
    72541 gctgtcattc ctttaacaga ttgataaata ttttggtcta gtggatatcc accatttgta
    72601 gttacaacaa tatcagattt tatagaattt acttttgata actctgttac aaatctacat
    72661 cctttagtat gtgctttttc gacatcacca gcaaaggaag caattatttt tttatcttta
    72721 tctattacaa cattcaatat gaatgctaat tttgcaactt tagctgcata taccatatcc
    72781 tcatgaatag gattattatt caattttcca gttcttgaat tatcactatc tataaagtca
    72841 ctacagtgat tgtacattat agtctttgca gatgcgattc ctggaagtac gctttttctg
    72901 ccacctgaaa aacctgcaaa gaaatgaggt tctataaaac cttctgctat caaaagttct
    72961 gcctcatatg ctagtttgtt tatatataaa tctccacctg aaggcaatat ccctacttta
    73021 cacatagatt tatcatcagt agatatatgc ataactatat cttcattatc tactatttct
    73081 tctcccattt tataaattag ctcttccctt gtacttggcc tatgaaatcc agttgccact
    73141 ataatcttca catcaatttc tggattaaca ttcctaatcc ttcttaatat aattggcata
    73201 gttattctac ttggtacagg tcttgtatgg tcacttgtaa ttatgactac attctttttc
    73261 cccttaacca gttcttccag agaattagag cctataggat tattcataga ttcttcaact
    73321 atctcttctt gagtcttatg ttctatataa ttatccgatt ttgactccaa aacaccgaga
    73381 aaacgttcat caggtatttc taaaatcatt ccttgttttg aatacggtac ttttaacttt
    73441 accattttta atctcccatt ataataaact ataaaattgg tatgtggtca taccagtttt
    73501 acatttatat aatagtacca ttatctacca tttgcaagaa taatttattt tataacaaac
    73561 ttttaatttt cattttttct ataattttta cttataaaat ccatatgttc ctttgctttc
    73621 tcacatgcaa gttctacatc attttctaca actgcattgt atatagcttc atgctgttta
    73681 agcaatatat tttcattaaa aggttctgcg attatttttt ctcttgcatc ttctataaat
    73741 ccatcaaata attttgatgc tgtcataaaa agactttgaa ttaaataatt tttacttaat
    73801 gttgctagtt tactgtgaaa tttttggtct aataatacca gtactcgatt attatctttt
    73861 ttattagttt ctaccctcat ttcatctatt atatgtttca attctataac ttcagaagaa
    73921 gttattctct ttgaagcaag ttttgcaatc tcaatttcta ggattattct aagctctaat
    73981 atatcttcaa gtgtaccatt attaagttta aaaatcatag ataaaggttc tattaaagtt
    74041 ttttctatat ttgtacatat aaaatttcct tcaccctgtc tgctttctat cactcccata
    74101 gtctctaata ccctaatagc ttcccttatg gaagttctac tcacattcat ttgttcagac
    74161 agttctcttt ctgatagtaa tttatccccc ttttttaact ctccatttag tattttatat
    74221 tgtatttgct caattacttg ttcataaact tttttactag ctatactatt aaacattttt
    74281 tcctccaata tgataatcgt tgttgtaata tatatctatt atatatctta agccattaca
    74341 ttcatatatt tttattactt ttaatataat atcttataac tcaaatttac aggtgatatt
    74401 atgaaaaaaa ataaaattat tgcttttttt gctccatcta tcatagttgg agttctagtt
    74461 ttagggatta tcctataccc aaatgaagct ataaaatctg caagagaagg cttttctata
    74521 tggtctaatg ttttagttcc atcactacta ccatttataa ttggagcaaa cttaattgtt
    74581 gatttaaaaa tagtggatat tatagggttt atcatcaatc ccataactag atttgtattt
    74641 aatgtttcag gaaagagcgc tttagctttt gctatatcta cagtatctgg ttatccagta
    74701 ggagtaagtt tagcttctga atttaggagt aatggacaaa tttctaagta tgaagcacaa
    74761 agacttgtgt ctttttgttc tacatcagga cctttattca taataggttc ggttggtaca
    74821 ggtatgttcc aaaattcaaa cttaggttat ttaatgattc tctgccatta tctaggaact
    74881 atattggttg gtcttttctt tagaaattat ggtaatgaaa accttccaaa gacaaaattg
    74941 gatttaaaaa caaatataaa aaatgtaatc aacattagaa attcaagtgg gaatggtttt
    75001 tttgttttat ttggaaatgc tgtatttaat ggagtaaata cattacttac agttggtgga
    75061 tttgtaattg ttttttcagt agtatttaaa atactatctc tttttaatgt aatatcatta
    75121 atagcatcag ttatatattt gcctctttca tttttaggtg ttagtaaaga actctgtcaa
    75181 gcatttgtaa gtggtctatt tgaaattact ataggatgca ataaagtatc tagtataaca
    75241 agttctccag aaattttaag agcatcttta gctagttttt tgataggatt tagtggatta
    75301 tccatcctag ctcaatgttg tacatttcta tcaaaaacgg acatagattt aaaattatac
    75361 atactaagta aatttgcgca tggagtttta gctgctatct ttatatttat actttatcca
    75421 attgcaaact ctgctgtgtt ggtttctagc tttgctgata catacaacgt tatatataat
    75481 aatttaatct ggttttatta tcttagctat tatgatacaa ttcttcaaat tgtagtaata
    75541 atttatctaa tctcagccgt atttattgca aaaaaacata tgaaaacttt atctacaaat
    75601 gggaaactaa tgcgatataa aaatactttt ttcactaaga aattttcacg aaaaaaataa
    75661 aactaaaaat aaaactaata aaacttaact aaatacttcc atttttttat tatatttgtc
    75721 ataattttaa taaccttttt aattagttta acagcatagt tatttcatca caatttaata
    75781 attttattag aaatattttt caaaaaattc tccttaatca catatatcac acttgtataa
    75841 gtttactggg aaatttttcc attatataat atttcattta tattatataa taaataccga
    75901 cctaaactta ccaaatcaaa ctaagaggag tggttgaaaa tggcaacaag acctatagaa
    75961 atagacgaat ataaaaagat aatggaacta ttacatactg gctttactta tagtgaaaat
    76021 ggcgttgaaa aaagatttag aaaaaatcct aaagttgcat tggcactaat gttagaagct
    76081 aatttaggtc taagaatatc agatatttta agattaaaga taggtaattt taaaggtaat
    76141 atgttggaaa taaatgaaaa aaagacgggc aaattacagt atagaccagt taataaaaat
    76201 ataattgagt ccataaatga acatgcaaga aagtataatc ttaaatcaaa tgactactta
    76261 gtaaatataa agacaaaggc tattcaaaaa cagttgagga taatttgtaa acacttaaat
    76321 ctgtataata taagtacaca tagctttaga aagctctatg ctactactca atttgaaaaa
    76381 agtaacaata atttagagtt ggttaaagaa cttttaaatc acagctctgt agccactaca
    76441 cagcgatata taagggtaac tcagcaagct attaatgaag ctagtgaaaa tttctttatt
    76501 ggttaattat aacgtataca tttttctatt atcttattaa ttcaccagat attaaaaaag
    76561 agtgtctcaa aatgaacttt ttagttcatg agacactctt tttttataaa atcaaatata
    76621 tttttattat ttcaacactg gaaaaaaggc ttatctctct attttgagac accctattaa
    76681 attttcataa ttcttgcata aacatattaa tctatcttca ataatttttt aactgattca
    76741 ctgtaattat ttctttttac aatttccaaa actctatcaa tctcatgttc tgactttgca
    76801 cttacaaaaa tcgccaattc ttcatcatct ataatatcat aactatctac atatttatct
    76861 aaacattcta aaattccatc tttattatta tacccaccaa atctaactac tgcactacac
    76921 tcatcttcta taagtccact taaatccaat ttcccttttg aaaaagactt tatatttgaa
    76981 cttctattat ctattatatc tataatatct gcataaacag cacttcctgt tgcacctctt
    77041 ccagctccct tacctacaaa agaaagttca cctactgaat cacctactaa aataactacg
    77101 ttgaactcat tatctatctt tgaaagcata ttattattgt ccactaatgc tggtctaaca
    77161 aatccactta cttctcctga ttcatactta cttctagcaa ccaattttat cttacaattt
    77221 aatttttttg catattctat atctttttca tctattgaag ttattccttc taataataaa
    77281 tctttccaat atactatttt tccataagat aaagtagaca atatagataa ctttctagca
    77341 ctatcatatc ctaaaacatc tgcatctgga ttaacttctg caaatcccaa ctcttgtgcc
    77401 tgttttaaag cgacatcata cggtaaattt tcatcataca tctttgataa tataaaatta
    77461 caagtcccat ttaaaatagc gtttatgctc tttatattgt tgccttccag tgattctatc
    77521 aatggtttta aaactggaat accacctgcc acagatgctt caaacttgat gctaacatta
    77581 tttaagttag ctaattctat aaggtcacta cctttttcag ccagtaaatc tttattagct
    77641 gtcactacat gtattttttt atttaacgct cttgttacat aatcaaaagc tggatttaat
    77701 cctccaatta cttcaactag tatatcaata tccttgtcaa atatatcttc tatatcagta
    77761 gttatcttat caaaatactt cttatacttg tgtttttctt tatttttaac taaaattcca
    77821 acaacttcta tatctctttt tgaagtatta ttttctatta aatcaattaa tccacttcct
    77881 actgttccat accctaatat tgctatcttc actgtaacat acccccatca ttttgattat
    77941 attaaattat ttatatatat aaatatacca ataaaaaaag cttgagtata aactcaagcc
    78001 atatgacggg tttatactca tctttcagca taaatgctgc aggatttagc accaatgtat
    78061 aattaaatat actggttgcc gggcttcaca gggccagtcc ctctgccact cttgataaga
    78121 ttgctaattt aaatttatgt ttaatagtat aatacaattt cttccaattg tcactatttt
    78181 tttaacttat ttccctaaaa ggatataaac tattatctaa cagctctttt agttggttta
    78241 cccttttttg taacattatt atttttagtc tttgctttcg cctgttcatg tcctggaaaa
    78301 agtattttag gctcttcaat attcctcttg taaatagtaa atttaaaacc aatagcctgc
    78361 acaaattcag ctcttaaagc ttcacatact gcattagcag tttctttagt atcaagacct
    78421 gcattttcta atatagtaac ttttactaat tctctagttc ttaacatacc atctaattgc
    78481 tctaagaaac tctctgtaac accttcttta ccaatttgtg tagtaggctt taaagtattt
    78541 gccaaagatc ttaaatacgc cctttgtttt ccttttaaca tattctcacc tctataattc
    78601 tatacttaaa ttatctataa tctatattta aattaattgt aaaactcaaa ttctaattca
    78661 taaattttaa ccacatctcc atcttctatt cccatttctc taagcctatc aaaaacacct
    78721 tgactctcca tagctttttg gaaatattga agggattcca tatcatcaaa atttacagaa
    78781 tacattattc ttctaagtgc tttacctgta actacataca caccatcttc aatatctata
    78841 cttaactctt cttcagtacc aatatcaagt tctggtctat acatttcttc ttctgaaact
    78901 agctccacat cttctacttc ttttagcatt ttagaaacat aggctattac ttcatctatg
    78961 ccttgacgag ttgctgctga cattttaaat actgtatatc ctctgccttc taattcactc
    79021 ttaaacttct caaacttact ctcatcttct aatatatcaa atttatttgc aactacaact
    79081 tgtggtctct ttgaaagctt ttcattgtac aatttaagct catcatttat cttgtcaaaa
    79141 tcttcaatag ggtctcttcc ctctaatcca gatatatcta caatatgtat caataccttt
    79201 gttctctcaa catgtcttaa gaactcatga cctaatccta tgccttcaga agcaccctct
    79261 ataattccag gtatatctgc aagtacaaaa ctatctccaa acttagtttg aacaacacct
    79321 agatttggtg taagtgttgt aaaatgatag tttgcaattt tgggtttagc tttagttaca
    79381 actgatagaa atgttgattt acctacattt ggaaatccta aaagaccaac atctgctatc
    79441 attttaagtt caagagttat ccatctttct tctccatctg taccagattt tgcaaaagct
    79501 ggagcttgtc ttactgcatt tgcaaagtgt tggttacctt taccacctat accacctttt
    79561 gcaactatag ctgtatctcc ttcttttttt aaatctgcta atacaagacc tgtagcctca
    79621 tctcttatta ctgtacctgc tggtactttt aatactaaat tttctccatt tttaccagct
    79681 ctttttcctt tgcttccgtc gccaccattt tgagcttgat attttttctg gtacttaaag
    79741 tccattagag ttctaagccc caaatcaact tcaaatatga tgcttgctcc acgaccacca
    79801 tctccaccgt ctggaccacc agctggaacg tatttttctc ttctaaatgc taccgaacca
    79861 tttccaccat ttccagcctt aacaaatatt cttgccttat ctataaacaa attcttcacc
    79921 tacttaatta aaaactttta attagcatta ccaaaaatac cattataaat tcatcagtat
    79981 tataagaaaa aggagtgcct caacactcct tttatgtata ttactcagct attgctactg
    80041 gatatatact aacttttttt ctcttcttgt cttttctttc gaatttaaca gtaccatcaa
    80101 ctaatgcaaa taaagtatca tcactacctt ttccaacatt agttcctgga tgtattttag
    80161 ttcctctttg tctaactatt atacttccag cagttactaa ttgaccatcg aatctcttaa
    80221 cacctaatct tttagatata gaatctctac catttttaga agaacctacc ccttttttag
    80281 atgctaataa ttgtaaattc atgtttaaca tatggagtca ccccctactt ttttaaaatt
    80341 tttatatttt ttgggtattc ccgtttaatt tctttaaccg ctaattgaaa gtgatttagt
    80401 aataattgtg cgtcttttac atgtgtatct ttgactatac actctatatg accttcttct
    80461 cctactactt tttcaaattc aatcttttgt aatttgtcta aagaatttat aactgcaata
    80521 gcattagatg taactgcagc acatactata tcatagccta tttcagcaaa atcagcatgt
    80581 ccctttaaac aaaaaccttg caacaagaaa tcatcattat aataatattt aacttttatc
    80641 ataacttaac caataactaa gcgtttattt tttctacaac tatcttagtg tatgattgac
    80701 gatgtccttg ttttcttctg taatcttttt ttgctttata cttgaaaact ataactttct
    80761 tagctttacc ttgttcaaca actttagctt gaacagatgc tccttctact actggagaac
    80821 ctaattttaa ttctccatct ttagagcaag ctaatacttc gtttaaagta acaacatcac
    80881 ctgcgttagc ttctaatttt tcaacgaata atacatcacc ttcagaaact ttatattgct
    80941 ttccaccagt ctttactata gcgtacatta aatacacctc ctcggcctca aactcgccag
    81001 tacaaggtac ttcatttgaa gatttaaacc tttactgtgc ggcattacaa ttattaatta
    81061 taaaatattt acattttatt gtcaactatt ttatcgaaaa taacattggt tttattgtgc
    81121 tttaatgtac tatttgcgtt taaagaaatc tttatattat atttttcacc aattttatca
    81181 attatatcca tataatattc ttttatttgt tcaaaaataa aatcattaaa ttctaccatt
    81241 atgtttttgt aaacagtatg ttcacttatt ctcataattt ctttttcaat actatctagt
    81301 atataatgta cagattttat tgtttgttca ccatcacaac atggacaaga cattaaataa
    81361 tacttatcaa tggattcttt ttctctacgc ctagcaactt ctactaaacc aagttttgtc
    81421 atacctaata cttcagcttt tcttttatct ttattaaatt cttcttctag gatgtgtaaa
    81481 atctcctttt gatgcttctt tttatgcata tcaataaaat cgattattat tatcccagct
    81541 atgtctctaa ttctaagctg tcttacaatt tcttttgcag cttcaagatt agttttataa
    81601 acggtttcat caagtttacc agttccaata aacttacccg tatttacatc tataaccgta
    81661 agagcttctg ttttttcaat tattaaataa cctccactct ttaaccatac ttttttattt
    81721 aataattttt ctattttaga ttctattctg tataaatcaa atacatctct attttcctca
    81781 agacacagtt tatcaacata agtcttatct atacctctta aaatagactt aagttcagag
    81841 tacttatcat aactattggt aattatagat tcaatatcat cattcacatt atcttttaca
    81901 tatttagttg caaaatctaa agacttatat aataatttcg gacctatacc aagtttatat
    81961 tcttttaaaa tgttttcata ctttaatttc aactcttcta tatctttctt tatttcatca
    82021 tgagtgcaac cttgagcctc agtccttatt attaatccta gattttcctt atttactgcc
    82081 ttagtaattt tttttaatct aaatcgttct ttttcatcag taattttatt tgatattgta
    82141 gttctatcat tggaaggtat atagacaata taccttccag aaatactaat ctcagtgttt
    82201 aattttgcgc ctttagttcc tatttcttct ttatttatct gaaccaaaat atcctgacca
    82261 gattttatag tacttccctt ttttaattgt aaataagcaa gtttcttaaa tccaatatct
    82321 acaaaacaag cttctattcc tggtataact ttttttacga ttccacgata tatattggat
    82381 acagtcttct tatttaaatt gtcttcaaca aaaagttctg ttaatctttc atcttcaagt
    82441 actgctgttt tctgggaccc tattagggac tcaataacta tctttttcac aacttcacct
    82501 ctcgagctta cataggagtc actaattccc catcttctaa tacatataaa tctcttctca
    82561 atatatcaac atctaatggg tcaatatcaa gttcaaacat ctctaatatc tttggtataa
    82621 gtatattagt atttaaatta gtttttgagc ctgtagctat agtagcagta agagtaatat
    82681 gttcatcttc taaatttaaa acatcaaagg ttcttatcat aggtcttata tctacttcaa
    82741 ccatcttacc ttttttattc ttttttgtta tgattatttc tttattattc ataaagtcaa
    82801 ttacttttct ttttacaaac tctttcgtca taggtctttt caaatctata ttaaacaaat
    82861 attctccata gtctatcaca gaagaaagag aaggtgtttg tctatcaatt tcttttgctt
    82921 tgataaaatc tatcccatct ggaagttgaa ttgatacttt atttaaaaat tcctctactg
    82981 ataaatcatc ttcttctatt tcaatatcta catactcacc ttgactttct gtccctaaag
    83041 ccaaagcatt gccataactc attttagggt gaggattaaa tccttgagaa tgtgataagt
    83101 ttatttcagc tcttctaaac gctctttgta acaatctctg aaggtcaaga tgtgatatat
    83161 atatcatgtc gccttccttt ttaaatttta ctcttattat cttactcata ttagcaaagc
    83221 ccccttccta tatcatgtat atttattcca caaccattgc agttatgtct acaatcagaa
    83281 gtgatttttt cttttttagc attttcgtct tctctaatta agaatttttt actaatacct
    83341 acatctatat ggtcccaagg aaatacctct tcatagtttc tatttctatg tgcataaaaa
    83401 tctatagaaa gattattctt ttccatagct tctttccata tatctaaatt aaaatgttct
    83461 gcccatccat caaatttagc acctagtcta aatgcatcat atataacttt tcctattctt
    83521 ctatcgcctc tagctactac tgcttccatc aaactagtct ttgaatcatg ataattgtat
    83581 tttatattgt tatttcttaa tttatttact aaatgtctct gcttattaat aacttcttct
    83641 gtagtatctt gaccatgcca ttggaaaggt gtaaatggct ttggtacaaa tgtagaagta
    83701 ctcactgtaa cactaaaact tctctttagc tttcctccat ttacttttct ataaatatca
    83761 ataactttat aagctaattt agctatacca tctaaatctt cataagtctc agttggtaaa
    83821 ccaatcataa aatacaactt aacactattc caccccatct caaaagctct ttctgttgca
    83881 ttttccaaat cttcttctgt aacaccttta tttataacat ctctaagtct ttgagttcct
    83941 gcttctggag caaaagtaag tccagatttt cttacttgtt gtattttatc agcaatttcc
    84001 attgaaaaat tatctaatct aagggatgga agcgaaatcc caatattatt agatgcatat
    84061 tcatctacca aataatcagt caactctgat aacttactat aatcactcgt actaagtgat
    84121 gataatgata tttcatcata tccagtattc ttaactaatt tatctaatat ttctttaagt
    84181 cttttaacac tcttttctct tattggcctg tatatcatac ctgcttgaca gaatctacat
    84241 cctctagtac atcctctaaa taattctagt actattctat catgaacagt atctatataa
    84301 ggtactatta gtttttctgg ataatctaca gtctcaacat cttttattat ccttttagta
    84361 ggatttttag taatcccttc tctattagga gttacacttt gaactgtacc atcttcattg
    84421 tacttgacat cataaaaact tggtatgtat actccttcta tgctagatat tttatataaa
    84481 aaatcttctc tagtcgtttt atttttcttc cattctttat actcatttac tacttctaaa
    84541 ttaacctctt caccttcacc taatattact acatctacaa aatctgctaa tggttcggaa
    84601 ttataagcac aaggaccacc aaccattata aatgggtctt ccaaagttct ttcttctttt
    84661 aatattggta tattggctaa atctaatata tttaagatat tagtgtatga aagttcatat
    84721 tgaagtgtaa aagtgacaaa atcaaagttt gttataggct ctcttgactc taatgcaaat
    84781 aatggtatac ttttttctct cattatattt tccatatcaa ctgcaggaga atacactctc
    84841 tcacaaaata catcttcatc cttatttatt acatcatata atatatgact ccctaagtga
    84901 ctcataccaa cttcatataa atctggaaag caatgtgcat atcttatcaa ttcactatta
    84961 ctagtatctt tatgaattga atttatttca tttccaagat atctagcagg cttttctact
    85021 ttttttaaga tttttttcaa gtctacttta ttcatttatt aaaattcctc caaacaagct
    85081 ctttattttt attcttattt ataagtaata ttatacacga taaaatattt tctatcaaaa
    85141 atataactaa aatattgaat ttaaaataca tattattcac aaaatagaat agctaaaaat
    85201 atttaagaat attttctatt aaatttttat tgaaatacaa ttttttcaca aagtatgata
    85261 tattataaac ataaaactat tgttttacat gacttatcat gacatctttt gtttcattca
    85321 cctcaaaatg gggtatgtta cttatataat gataaatttt aggagggtta aaaatgagta
    85381 aagtttttga agtaaaaaaa gatatctact ttactggcgt agtagatgaa ggtttaaaag
    85441 tattcgacat aataatggaa actgagtttg ggacaactta caactcttat ttaatcaagg
    85501 acgaaaaaac ggttttattt gacactgtaa aggcaaattt taaagatgag tttttaagta
    85561 atttatcaga ggttactgat atagctaaaa ttgactatgt tgtaattcat cacacagaac
    85621 cagaccatgc aggtagttta aaatacttat tagatataaa tcctaatata gaagtttatt
    85681 gtactaaagc tgctaaacta tacttagatg gtcaaataaa tagacctttt aactgtcatg
    85741 taataaaaga tggtgaaatt ttaaatatcg gtaaaagaaa tcttagattt ataactgctc
    85801 cattcttaca ttgggttgat acaatgttta cttacattga ggaggacaag actcttttaa
    85861 cttgtgatgc atttggttgt cactttgcaa gtgttgatgc agaggtagtg aatagtgaag
    85921 attatctaaa atcagctaaa cactactatg attgtatagt taagccattt gctaaacatg
    85981 ttttaagtgc tgtagataag gtggtaggac taaacataga atttgatact atattgactt
    86041 ctcatggtcc aatgcttact aaagacccaa tggctgctgt taaaagatat gttgagtggt
    86101 ctacagaagc tgttaataca actaatcaaa atcaagtttc tatattctac ttatcagctt
    86161 atagtaatac tttagagatg gctaaaaaga taaaagaagg acttgataaa gaaggtgcaa
    86221 aggctgaatt atatgattta gaagatatga cattaacaga aatgcacgat acattagtag
    86281 tgtcaaaagt aatattacta ggctctccaa ctataaacaa aactatggtt aaacctatgt
    86341 gggatttatt ctctgttata gacccaatgg ctaaccaagg caagatagca ggagtatttg
    86401 gttcatttgg ttggagtggt gaaggtataa ctatggctga gactttactt aaatctatgt
    86461 cattcaaaat gcctgtagaa tctcttaaga aaaaattctt ccctagtgaa gagacattaa
    86521 aagagtgtat ggcatttggt gcagaatttg caaaattagt taaatagcca ttaatcacac
    86581 ataatattat ttaaaataaa tgattttata tttaaaaata aattaaaatg gagttgtctc
    86641 aaaattaatt tttctaatct aattttaagt tcaactcctt ttttattttc taaaatgact
    86701 gatataatga taaatgcacc ctttgtgcga gggtgcatta tttataatat gttctatttg
    86761 tacactagta tatttgtatt aattcacata tctagcgtat gctaccatcc ctcttccaga
    86821 attagatgcc gtttcaccaa tttccacttt aataattaca ttattttctt tacacttttt
    86881 tgataattct gctgcagaaa ggttcttacc agtaaaatct aaagaaaatg gcttatcata
    86941 ttcaaaagga tactcatcag gtacaccatc tggagctaat gcaaccatac catatggtgt
    87001 attcataaac cctattacag taactgtatg ctttgatggg tctaaatttg aatttttgct
    87061 tgtaaactta attgtattta ttgatgagtt gattaaacta cacggaactc cctcatacat
    87121 ttcaattttt ggacgtagat tatttccata aacttcatca agtattgccc cttgttgatc
    87181 tgctatcata gtgtgattcc caggtccaac tggcgcagaa ggcttagctg gcgtaggttt
    87241 cttaacagtt ggcgttggat tctgtgtctt tactacttcg ccaacagctg gatatgcttt
    87301 cttgtcaaat ggtaatgggt gagtaagact cttgtatatg atgtctgctc ctgctgattt
    87361 gttggcatca atatctacat gatacaaacg tccatcctca aaacgaataa gattccactg
    87421 atggtcattt gttgtactat gtacataata acattcaatt cccatagcat cacataaagc
    87481 tttcaagctc ctacacattc cagaacaagc acctttttta gtaaccaatg tataagcagt
    87541 attggctccc tctgctgcgt tccagttaac atatgttgtg ttgtttttaa tgtgattata
    87601 agcaacccta atcttagcat ctgtggtcat gttctttgta attttcttgt tcataaagtc
    87661 tgctgttgct tgtgctaccg aattaagttg agcttgtgat aactttggac catatatact
    87721 gttggttcca gctacataac ttttcggtgt ctttgcagta acatctttag ctgtcatacc
    87781 ataaactgtt acactcatac atgaggttaa aaccatcgtt gcaatcaata gtttagtagc
    87841 taatttcctg atttttttca tattagcatt ctcctttata atatatttta ctttcaattc
    87901 cctaccatta attaagttca ttttagattt aaaatatgga ttatcaacat gtatgcatag
    87961 caattcacgt ggtcatagaa tatttagatt tcttggaaaa tctgttctat atttcctata
    88021 tagttcgtat acaatccaac tcacaaacct gcatttttga tatcatcaca ataaaatgat
    88081 aataattaat atattcaaaa atgttggtct gtaacaggta tgtcaatttt ccaattattg
    88141 gtaatggcga gagtgaggag aattgtcaat aatacattta aaattaaaat tgtatacact
    88201 tcatacattc tcccctaaca acattataca gattataatt tgtatattca atacattttt
    88261 tggaaagtat aattatatca aaatatgtga ttatgtatag atacaatcca ctatggagaa
    88321 atataaaaga aaagagtata acaaacaata aaaaataaga tgattcaaat tttattttga
    88381 aacatcttat ttactctaca aattaagatt atttggtgaa ttatttaatt attatttttt
    88441 attaaagaaa ttttaaatct taatataaaa tacgctatta tacataataa tccaaatgca
    88501 aatgctactg gaattaacat ctccgattca aaataaaaga aatattctaa gaaaatatct
    88561 ggatttacta tattcccatt cttgtctaaa aaatcttttc cattatatcc taaatgctgt
    88621 ataaaattac ttatgttatt ataatccgct tccctctcat ataccatatt agcattcaat
    88681 ccagaagaac ttaaattagt gtttccatct ttcatatcta ttacatatag tctaagagct
    88741 ttgactttac tatacttatc tttatcaagt attttttcaa gttctaactt atattcacca
    88801 atctttgtca tatcatgtct ttctgccaat tgctttattt ctccatcaag ttcttttcct
    88861 aaattataca tattatgttg taaactatta ttgtaatacc acataaatcc agaaattaaa
    88921 aatgcaatta tacttatgta acctaatact tttttaaacc ccattacaat tgatttatgc
    88981 ctatccaatg ataaagatag ttcttttatt atattacata attcatactg catttcatca
    89041 ccatcatcaa atctttcaat tgctttttta catgcttctt cttcatctaa tccttctaat
    89101 ttaaattcat ttgcagattc tataagatgg catctcattt cctgttttaa ttctatagta
    89161 cttttattgt cacatttttt atatagttta tctaaatatt catctattag tttcataaat
    89221 taatccacct ctcccaaaaa ttgattcata acctttttaa taaatctcca ttcttgtttc
    89281 tttatttcta aaaaatcttt accttcatta gttaaattat aatattttct tcttccacct
    89341 gaactttgtt cattgctata ataagattta attaaatttt tagattccat tcttttaagt
    89401 gcaagataca ttgttccttc ttttaattca aactcacttc tttctcttac ttgctttgca
    89461 atttcatatc cataacaatc tttcttttct aatatagaaa caattaatat atcgatataa
    89521 ccttttaaca cttctttatt taactgcatt atgtaccacc gccttttcac ctactactct
    89581 ataatgtata gtacttatat ttactataat aatacatagt actctataat acaaggttta
    89641 tattctacaa tagacttaaa aataataaat agctgtatat taatatttaa tctataaata
    89701 ctaatataca gctatttatc aaattttaaa aataaatttt tgttttatta atgttgtcat
    89761 aacaacattt acttggttga aatagtatta cctataagtt taaatatata taataataga
    89821 cttgattcta tttcatatta ttaaaataga gtaatagttt aaattctact actctatcta
    89881 taatctattt cctaattatt taatctcaaa tttagctctt catcatttaa atctttcata
    89941 agatttctac aggtactaga tttattccaa cagaaaaact agggcattaa acacttatat
    90001 atctgtttct ttagactgta atattaatat tttttaaata cgttgacttt tgctttttct
    90061 aacttctctc catgatagtt ctcctctatc aagagctttt ataaatattt ctgctgaagc
    90121 tagatttgta gctattggaa catgataaac atcacaaagt cttattaacg cttgtatatc
    90181 tgtttcatga gcctgagatg tcaatgggtc tcttaaaaaa ataactaaat ctatttcttg
    90241 tgttactatt aaagaaccta tttgttggtc tccacctaaa ggaccagatg ctaatctatt
    90301 tatatttaat tcagtttcat ccattattct ttttcctgta gttccagttg catatagtcc
    90361 atactttttt aaaattgatt cataacctat acaaaatccg accatagtgt ttttcatttg
    90421 gtcatgtgct actaatgcta tattcatata tctaatctcc tcaatttatg tttagatgta
    90481 tttaaattta gaaatttatt ttctttcttc tcatacacac atttagtact aatcctaagt
    90541 ttgctaaaga tgtcaataac gaacttcctc cataacttac aaaaggtaat gttactccag
    90601 ttactggtat taacgcaacc gtcataccta tattttggat tatctggtaa ccaaacattc
    90661 ccataacacc aaccactatg agggttccat aaaaatcttt tgcatctctt gcaattgcta
    90721 aaagccttaa taggaatatc ataaataaga ttatcaacac tgccattcct attacaccaa
    90781 gttcttcacc tacaacagca aatataaaat cactatcttg tacaggtaaa aaatcttctt
    90841 gattttgact tccattgtaa agtcctttac cagttacgcc tccagaacca attgcaatca
    90901 gagattgcat aacttgatag tttcctttta gagttacatc ttctggattt agaaaagctt
    90961 ctattcttac cttttgatgg tctgccatca ttaaatacat cagtggcatt gacactaata
    91021 gtatgattat tcctcttttt atcaactttg agctaagacc tgctgtgaac agcattgcaa
    91081 atatcataca acaaaataca attcctgttc ccaagtctgg ttgtgcaatc aataatccga
    91141 taaatggaag agaataaact acaacaggca taacttcctt taacgtattt aatttatcct
    91201 tcttggattc aagtatcttt gcataactta gtacaaatgt taatttgact atttcagatg
    91261 tctgcaagtc aagtggtcct aagttaatcc acgacctagc tccacctttt actgtcccaa
    91321 ttccaggtaa taaaactatg gctaacaaaa taagacttat tatataaagc gctttataat
    91381 acctgcctag aaggttatag tcaaaaaata atatgactat aatcattcct ataccaagta
    91441 caaaagctaa tccttgttta atcaattgat tatatgaacc tgttgaatta gcatgtgttg
    91501 cactactaag tataacaagc ccaaaaataa agatagctaa tactgtaact ataagtttcc
    91561 agtctaactg ttttatcaac ttaattgtcg acttataatt aatattgatt tttttcaaag
    91621 aatcaccgtc tttctatctt taaacatata attaaataaa aggggcatat accaataagg
    91681 atatccccct tttaagcact aattacatac atctatcttt tatattcttt agtggtatat
    91741 tagcaactaa tgcagataca ggtttgtcat catgctcacc tctgcattta gacattttta
    91801 tttcaaggcc atcatcttct atttctgcat aattagctat tacttttaaa atgtctgttt
    91861 ttatcatctc taaaagttgt ggtgaacaat ctactctatc atgaactaaa actagcttta
    91921 acctctcttt agcaacagat ttactagttt tagcctcgtt agaaaaaact ctaaataaat
    91981 ctaacacaga tgtatcctcc tttgctactt agccatgcta aacatttttt taagtctacc
    92041 aaagaatcca tcttcaactt caagatcaag tagaggaact tcttcattta gtatcctttt
    92101 tgcgatattt ttgtatgctt gaccagcaag tgacttagaa tcaagtatag ctggctctcc
    92161 tttatttgtt gatataatta tgctttcatc atcaggaaca agacctaaca aatctattgc
    92221 taatatttct attatatctt gtttatccat catgtctcca cgcttaacca tatcatttct
    92281 aattctattt ataactaatc ttatctcttt tatttcattt gcttctaata gacctattat
    92341 tctatcagca tctcttactg ctgatatttc tggattagta actacaatag ctctatctgc
    92401 tccagctact gcatttttaa agccttgctc aatacctgct ggacagtcta ttattatata
    92461 ctcgaaagat tcttttagtt tctcacacag gtcaatcatc tgctcaactg agacagcatt
    92521 tttatctcta gtttgtgctg ctggtaataa atatagatta tcaaatcttt tgtcttttat
    92581 tagagcttgc ttaagcctac aagttccttc aactacatct actatgtcat aaactattcg
    92641 attttcaaga cccattacta catctaagtt tctaagtcca atatctgcat ccacaactac
    92701 tgttttttta ttttctaggc ttagcgcagt tcctaagttt gctgcggtag tagtttttcc
    92761 aaccccacct ttaccagatg ttataactat aacttcgctc ataatactac cccctatttt
    92821 tctttctatt tgtctaactt tgacaaatag ctttcgatta caattcttcc attacttaca
    92881 aaggctattt ctgggctaat ttctgattca ctttcataat tttcttcatc atctggagct
    92941 tctgcaatat tatctgctat ttgtaatatt ttaggattaa gatttccagc aacaacatat
    93001 gcaaattcat tgccttctgc acctgcatgt acaaaacctt ctattttacc cattacaaaa
    93061 acattacctc ctgctacaac cttagcacca gcatttatat ctcccataac aactgtattt
    93121 gattttgaaa ggacttttga accaggtttc atatcattca atataactac atcaccttca
    93181 aattcaatat tttcaccaga tcttagggta ttgacatatt ttgttggaaa attactattt
    93241 tcttcaattt tttgatcttc aacaaattcc acatcaaatc tagaagtaat tccttcttta
    93301 agttctagaa tctccatgtc agttaaacaa tcactattaa ttttactaat tttagcccca
    93361 ttaaaaaagc caacatatgc ttccaatttg tttattattt tttcctgtat ttcctcaaat
    93421 ggagcttctc tttttatatt tactattatc cctcttttat tacccttgaa ctctactagt
    93481 tcttgactac aaatttctct taaagacata acaacctcca gagtgatata tcatttatat
    93541 tcttcaaata cgctttaaac ccttttattt tttctatata aagctaaagt ttatacatag
    93601 attgagctat ctattaattt gtgactcgaa atttatattt tcgtcagaag aattgttaac
    93661 atcattcgtc ttgttgtcat ttttactatt agttggctct aatcccatat aagttccaat
    93721 aacttctcta gttggtaaaa gtgagaatac acttgaatca ccttgaggaa ttacacatac
    93781 aacagctatt tctgggtcat ctgctggagc aaaagcaaca gtccacgtaa aagaaccata
    93841 atcttgttta aatctatcta tttggtcatc tgttattttt ggatttaatt cttttatagc
    93901 ttttcttaga tatgaagaat tcaccttatc agtgtcctct aatctaactt ttactccatc
    93961 ttctaattct tcctctaatt tctttctttc ttcgtctttc aaatctttat tttctaattt
    94021 cttttttatt tccttttcct tagctaatga aagctctttt tctttttctg ctttcatctt
    94081 atcagctagt ttaatcgcat catttaggtt gacattataa gatgacatat gactttttaa
    94141 atattcatac tcgttatctg taggtatttt cccacttttc tcagctgtac cagtttttgc
    94201 tgctacatct attggaaaat cagcaaaagc actcttcgct gtaccttgtc ttgcaaccaa
    94261 tttcatacct tttgttaatt cttttaagtt atctggattt ttaaaaggta ttttttcgac
    94321 tttcttctga tcattaattt taactgatga ataatcactt gaaacagctc tatcaactac
    94381 agataattct actaaattac ctccatttgc tatagcagcc acatatcttg atatctgagc
    94441 tggtgtatag gcattctcac cttgtcctat agctaagttg aatgtatctg cagtactcca
    94501 ttttgcaaag ttaaaataac tgaatactgc taaatctgct acttcttcaa ttctatcttc
    94561 tttaacatcc aattttttta gcctattcat tgtttcaact ctaccaggag ttttcttttc
    94621 tgctgcccag cttacaatct cattgattct tttctcatat tctttaggat ttttttctct
    94681 agttatatca acaaaatcat ttgccatttc tctttctaaa tttgacttta gaagagcttg
    94741 tgttgatttc aatttatctt ctgtgctagg aactttacct gctctttctt ctacttcatc
    94801 ttgaagccct gtattttggt caagcccaaa taattttgca tactcaagta ttttatttgc
    94861 attcatatct ataccaatgc tttttccatc tggccatgtt ttacctgtac caattgttgc
    94921 catatatata ttacaagact cttgtattgc tttatataag tttgtcatac catggtttcc
    94981 tctaccatgg ttccatacat agtcaccaaa agatttttta cctaacatta taaccccagg
    95041 gtcatttata gtaaagtttg gatccagacc attttctaac gctgccattg aagttaccat
    95101 cttaaatgaa gaacctggct gaaattcccc ttgtgtaacc aagtttaaaa gtggacttcc
    95161 tgctagtaag tcatttggat tttttggttg aagtgcttta taatcctctg tagaaatacc
    95221 ttttgcaaat ttatttgggt cataattagg ataacttgat gaagctaata cttctccatt
    95281 tttaacatca atagctataa gagctgctga ctgtgctttt cctgcatatg cactaattgg
    95341 tttgtcccca aatttacttt taaaagtacc tcctttagaa gcaacttcga ttatctgttt
    95401 taatgcatta tctgaaactt cttgtaaatc tttatctagt gtaagataca cagtatctcc
    95461 tgatttaggt tttttagatt caatttcttt actgattcta cccaatgcat caactttaac
    95521 cattttataa ccatcagttc ctcttaatct actttcatta ctcttttcta ctcctgcaag
    95581 acctaccata tctccagttt cataaccttt ttgaaggtat gattctattt gagtggatgg
    95641 catttttcct acatatccta acatatgaga agctaatgac ccattaggat aatatcttac
    95701 tggttctact gctattgaaa caccaacaag gtccatagca ctttcttcaa tttgagcaat
    95761 cgtagtttct cccacatcct tagcaatagt tactggatta tattgagaat atccttttga
    95821 ttttatcaaa tcccttacga ccattatttt tcttgcatct tcatcactca aacttttatc
    95881 aatttctaat gcatcactat ttcttacttt ttcaaacgct tctttggcac tcagtttagt
    95941 ttcttttatc ttataactag ccaaccaatc tctcttatct ctttctgctg tgaacatcca
    96001 tttactaact aaaataggtg gataatatcc attttcattt agttttgcct gtaatcttgt
    96061 cgcatccaat cttttatctt cttgagataa tattccagct gatataagtt tgtctaccaa
    96121 gtaataaaaa ctttccttag cattataatc atttggaata ccattttctg atttatattc
    96181 cctaatatct ctgtcatatg tataatagta ctttccattt tctacatata taggaaactc
    96241 atctacatat tcttcaccat ttctctccag caaatttata agttttaatg atatttcatt
    96301 tgctcttgaa tgcttatttg catctttctt attaatatcg ttacctgaaa cttgaacagt
    96361 aaataagttt ttatttcctg ccaacagtct tccatatcta tcttttattt ctcctcttgg
    96421 agcttctatt gccaactttt tatatgtttt attctcagct aactcattgt aatattcata
    96481 tttaaatgta gtcatataga ttatttttac taaaatagct aaaaatatca cgcccatgac
    96541 tatcttaatt atttttagtc tatcaacttg tttattttct tccatgaaat caccaactaa
    96601 tcttctttaa gttttaaaac tgctctttta gataagcgat atattactaa accaattaaa
    96661 ctattcacta ttggtgctac tagtagacct tttacaaaaa gtgttgatat gttgtagctt
    96721 tgataaatta tactagatgt acctatattg acaattgaat caattaaact gcctataaaa
    96781 attaaaacga aagtaataat ataactacct ttatatagct gatctctcat gtatccaatt
    96841 gcatatgcaa taataaacaa aattaatgca tttacaccaa aaattccacc aacggttatg
    96901 tctttaataa gccctattat tgctgctata atcccacctt ctaattcatc taaataaaga
    96961 gagattatgg ttacatatat aagaactaaa ttaaagctta tgccaaaaat atctatataa
    97021 tttgttatac tattttctat agtcataagc acaatcccca acagacaaag taaaactttt
    97081 ttcattgttt ttatcccctt tatcctatat ttcttggttc tatgactaca acgtcattta
    97141 tattcttaaa atcaacataa ggttttacaa ctacatattt taatgactta tctttatcat
    97201 caaccacttt ttcaacttcg ccaattggta taccatctgg gaagaatcca agacctgatg
    97261 ttgttattat atctccttga attacattat atgatgagtc aaacatatat ccttgcaaat
    97321 atcctttact attataacta tctttattat ctaaagtagt attttgagta attgtacctt
    97381 tagcattggc atcctttgct agtttaaagc ttacagatgc cttagaatcc aatagtgaaa
    97441 ttgccttact ataattgttg gaaacttcat aaactatgcc aactaatcca ctaccattca
    97501 taactatact ttcttttttt acacctgaat tttttcctgc acctatgaca aaactctcat
    97561 accagtttcc atcattttta ccaacaacac ttgctgaaat acttgtcgcc ttatactctt
    97621 cttgtacaaa gttcagtgtc ttttttaact cttctagcga ttctgtttta tctagtttgg
    97681 catttaaagc tatcatattt tttttaagtt tttcattttc ttcttctaat ttttttacct
    97741 ttttagaatt atctttaaaa tttgctacat ctttaaaacc atttttgata aaagaaaatc
    97801 catcatttat tcccttacct acacttgtaa tagcatctga agctactcct aaatttactg
    97861 gactaccact agaaaattta ccaattgata tacccacaat tccaattaaa gtgatagcaa
    97921 ctacgcccgt tgctatcact ttaacattaa tccttttttt ctcatttttg ttcttgtcaa
    97981 atctcaaggc catcaccaac ttctaattct tagtattcat cattaatact ttttcaaaga
    98041 tttcttggtc ttcaacagat ttacctgttc caagtgcaac acaatcaaga ggtgtttctg
    98101 ctatttgtac agacatacca gtttcctgtg taataagctt atcaagacct ctaagcaaag
    98161 cgcctcctcc tgttagcatt attccgtttt ccattatatc tgaggctaac tctggtggag
    98221 ttctttctag tgtagatttt attgcatcta ctattgaact tacaggttct tttaatgctt
    98281 ctctaacttc tgtagagcat atttctattg ttttaggtaa tcctgagatt aaatctctac
    98341 ctcttatttg catatttatt tcttcatcat ctttaaatgt agaacctatg ttaattttta
    98401 cattttcagc agttctttca cctatcataa gattatattc tttttttaca taagccacta
    98461 tagactcgtc aaattcgtct ccacctattc ttatagattt agcagtaacg attcctccta
    98521 aagatattac agctatttct gaagtacctc caccaatatc aactaccata ttaccttctg
    98581 gttcttcaac ttttaatcca gcccctatag ccgctgccat tggctcttct ataaggaatg
    98641 catctttagc tcctgcttgt cttgcagcct cttctatagc tctcttttct acttctgtaa
    98701 ctccaaaagg aacacatata gctattcttg gacttacaac acctttttta tcagccgctt
    98761 tttgtataaa atagctaatc attgattgag ttatgtcaaa atcagctatt actccatctt
    98821 tcataggtct tatagctact atatttcctg gtgttctacc tatcattttt ttggcttctt
    98881 cacctactgc taatacctct ttactatcat ctcttattgc gacaactgat ggttctctaa
    98941 caacaatacc ttgtcctttt atgtaaacta atgtatttgc agtccctaaa tctattccca
    99001 tatcctttgt catcttatta aaactaaaaa aacctttttt ttctttcttt ttttccttag
    99061 ccatgatttt actccttcct actattaaga atcatgttta aaacattctc ctattatttt
    99121 atcacatata aagtcaaatt atcatatttt ctttaaagct aaagtataat ccatctccaa
    99181 taattatatg gtctattatt tctattccaa ttatttctcc acatttaata agtcttgatg
    99241 tgatattttt atcttctctt gatggttcta cacttcctga agggtgatta tgcatcacta
    99301 ttatcttact tgcacttctt cttatagctt ctttaaaaac ctctcttgga tggactaatg
    99361 acgagcttaa agtccctata gatacatcta catcagatat tatctcattt tttgtgttta
    99421 aaagaaccgc tttaaaaacc tcttttttta aataccttag gctatccata taatacctct
    99481 gtatatccca aggattcctt attttatact ttataggttt aaaactagct actctagagc
    99541 ctagttctaa agctgcttta atttgggttg attttgataa cccaattcca tctatattac
    99601 acagctcctc tattgtcata tcttctaaat gtctaatacc ctgaatatct ctatttatta
    99661 tatagttggc taattcaata gcatttttat tcttgttgcc agttcttaaa agtatagcca
    99721 acaactcagc atttgataag ctttttacgc ctttggcaag catcttttct ctgggtcttt
    99781 cctctggtgc catttctttt accttaatgg ttgaattaaa tgactttttc agataaatca
    99841 cactccataa aaaagattta tactaaaata tttttttaat aggtcgccta accttgaaat
    99901 tggaagacca actatattaa aataatctcc tctaatttct tcaactaaca aagctccata
    99961 accttgtata ccataggctc ctgctttgtc aaatgactca ttagttttca gataatcctc
   100021 aatatcctgc tctgataacg ttttaaattt cacattgctg attacatagt caattacctt
   100081 tttatcttcg cacaagttta ttaagctaat acctgttatg acttgatgct ctcttccaga
   100141 tagtcttttt aacatatctc ttgcacaaga ctcatctttt ggttttccta aaatagcatt
   100201 gtctaaaaca acaactgtat cagctccaat aacaacatct tcattatgtt cagatgctac
   100261 agacatactt ttttcaaaag ctaatctcat aactaaatgt tttggtgttt caccttccaa
   100321 tataatctca tcaatttcat ttttaattat atcaaatctt acattcgtat tctctagaat
   100381 ttctttcctt cttggagagg ctgatgccaa gattatattc atttattcac ctcatttgta
   100441 cgtaatttgt acctatttag tctatcacta tattgtaaaa aattcaacag aaatgtcgaa
   100501 ccttttttgt tacactattg ttatatttat taccattaga ataaatatac ataaaataga
   100561 ggtatggaaa ttattccata cctctgtttt atgtactcat tagagatatg gaaattattc
   100621 catatcctta ttttgtccat attacaaaat tttaatagct ttctttggac atttttccat
   100681 acataaatgg catcctacac atttatctgc atctacctta tgtttttctt ttaattctcc
   100741 ctctattgca tcaaacttac attgtttttt gcacactgta catccaacac aaagttcttg
   100801 gtcaatagta actttctttt tcttagttat gtcacctgat attacttttg tagggcattt
   100861 tgctacacat tgcatacacc ctacacactt attagggtct atcttagcta ttttgtcttc
   100921 aaatattatt gcatcaaatt tacaagcttt tacacacatt ccacagccaa tacatccagc
   100981 agtacatttt tccttaacag ctttaccaaa ctctttgcta ttacactcta caactacttc
   101041 ttgactttct ggttttgtga ttattatacc cttaggacaa acttctttac attttccaca
   101101 atttacacac ttttcttcat ctattactgc tattccatca actatagaaa tagcatcaaa
   101161 tttacaagca tctttacatg ttccaagacc taaacatcca aatttacaca tcttagcacc
   101221 tgagtttaaa acatttgctg ctctacaatc tgatattcct tcatactcat atttatcttt
   101281 tgcacttgaa caagttcctt tacaaataac ttttgctact tgtttctcac ctgcttcagc
   101341 acttattccc attatttctc caacttttgc accaacatct gctccaccta cagggcaacc
   101401 attaactggt gcattgcctt caactatcgc atttgcaaga cctccacaac ctggaaatcc
   101461 acaacctcca cagttggctc ctggaagtac tcctagtata gcttccactc tctcgtctac
   101521 ttctacagca aactttttag atgcaaaatc tagtactatc ccgaagatta agcccataat
   101581 tcctaaaact aatacagctg taagtatcac cattttcacc cctctttttt atagctttat
   101641 aagtcctgta aatcctaaga aagctattga cattaaacct gctgatataa gcgttatagg
   101701 gaaaccttta aatgcttctg gtatatcagc taattctagt ctttctctta tacctgcgaa
   101761 tattactatt gctaaagtaa atccagctcc ggctccaaat ccgtttatta ttgtttctac
   101821 taaattataa cttttttgaa cattaactag agctatacca agaactgcac agtttgtagt
   101881 tataagaggt aaataaactc ctaatgcttg atataaagat ggactcatct tttgaattac
   101941 catttcaacg aactgaacta tagaagctat aaccaatata aaagctattg tttgtaagaa
   102001 tccagttcca gtttttacta ataaaatctg tataaaataa gttataattg aagctagagt
   102061 taaaacgaac gtaactgcaa ctcccatccc tactgctgta tcaaccttct tagaaactcc
   102121 caagaaagga catataccca agaattgaga tgttataacg ttattaacaa gaacgatact
   102181 taaaaataaa agtattaaat tcatttatta cacctccact atgctttttt acttcttaat
   102241 ttattaaatc ctgcaaataa gaatcctaat gttaagaatg cacctggtgg taatataaat
   102301 attaatactg gttggaaaga tgctccaaat aatgtcattc caaataaact accatttcca
   102361 agtaattctc ttactgcacc tattattgta agtgcaacag taaatccaag accttgacct
   102421 acaccatcaa ctattgaagg catagctcct gttttgaaag caaaactttc tgcacgagct
   102481 aatattaaac agttaacaac tattaatggt atatatatac caagagcctt atcaagagca
   102541 ggaacatatg cttttaaaag catacctact attgtaacaa atgtagctat aactactata
   102601 aatataggta ttcttatctt atctggtgta atttttctta ttaaagatat aactaaattt
   102661 gcacatatta aaactgctgc tgttgaaaga cccataccaa ttccatttat tgctgaagtt
   102721 gtaacggcta gtgttggaca catacctata acttgaacaa atgttgggtt ctcatctatt
   102781 agcccatttt taaatacttt agctaaattc ataattaacc ctccttattt attaagagca
   102841 ctattgaaaa catctatagc agcatttact cctgtagtaa ctgctgtaga tgtaatagtt
   102901 gcacctgata ttgctaatat ttgattatct gctgttgtac ttccttttgc tacttcaaga
   102961 ggctcagcag tttttccttt gtattgaccc ttaaatgcat catccttagc ttttgctcca
   103021 agacctgctg tttctgacat attaccaatg tcaacacctg taacttgacc ttcagatgat
   103081 atacctacca taacttcaat ttctccacca tatccacttg gtttagcttt taaagtatat
   103141 ccaaccactt cagaaccatc taaaccttca tacacttcag ctataagatc atctccaagg
   103201 cctttgtaag tatcttcctt catttcttta aattcttttg cttctggaag gactgctttt
   103261 ctaagttcat tatttgcttg tatatttctt tgttctatta ctggagctgt aacctgatta
   103321 gtagctccaa gagctaatgc agctattgca cttatagcaa gtaaagtacc acctaatctc
   103381 accatactgt tcattattta gccacctccc caaatactct atttctaaca aacttatcta
   103441 taagtggagc aagacagttc actaatagta ttgagtaaga tacaccttct ggatatccac
   103501 catacattct tataacagtt gttataagac cagctaatac agcgtatatt atttgacctt
   103561 ttttagtcat aggcgaagtt gtataatccg taagcatgaa gaatccacct aacataagtc
   103621 ctccagcaaa cagttgatat attgcgaaag ttatattaaa tccacctaaa aggaatgtta
   103681 atataaatac agttgctatg taaaatactg gtataacata atttattatg cctttataca
   103741 ttaggtatac tccacctaat aataataata ttgctgatgt ctcacctata catccaccaa
   103801 tattccctat catcatgtca gcaagactaa ttccattgct agaaaggtct gccagtcctg
   103861 ctgctccatt tttcaaaaag cttaatggag ttgctgtagt aactgcatct aaatttttac
   103921 ctatccagtt aacacctggt tgagtccaag cagtcattgc tactgggaat gatgctaata
   103981 aaaatgctct tgcagcaagt gctggattga caaagttaca tccaattcca ccaaatacca
   104041 ttttaactac taatattgca aatattcctc ctactagaca catccaccaa ggaagtgatg
   104101 ctggtacgtt aaatgctaat aataatcctg ttacaacagc tgaaaaatct cctatagtac
   104161 ttttttgctt cgtaaatttt tgatataaaa attcagtacc tactgtacca agtatacaaa
   104221 aaaacatagc actcaaagca ttaagtctaa agaagtatac tcctgctact gctgctggaa
   104281 ggagtgctat aataacttgt ttcattatat atgaagtatc ttcattactt ctcacatgag
   104341 gagaagatga tactatcaac ttattttcca tcgtttttcc cccttaactt tctttatttc
   104401 tgagcagctt gctttcttct ctttgctcct atttctctct ttgctgatct tatagattga
   104461 agtaatggtc ttcttgctgg acaaataaat gagcaagacc cacattctat acaatccatt
   104521 gctctatgat attcagctgt gtcatagtca tcttttaaag aatatgcact tatgaaaagt
   104581 ggttgtaaga atgatggaca tacatctgta catcttccac atcttaaaca gttttgaata
   104641 tctggagtac gtgattcttc ctcatccaaa cataaaattc ctgaagaacc tttgttagtc
   104701 gctatttcag tagtatattg agctattccc atcataggtc cacccattat aaccttacca
   104761 atcttcttat cttctttaaa tccaccacat tgttctatta tttctgaaac taatgttcca
   104821 acttttgtta ttaggttctt tggctctttg atgcaactac ctgttattgt agtgattctt
   104881 tcaaccaaag gcatacctgt tttaatagac ttagctatct gtgctgctgt ggcaacgttg
   104941 tcaacaactg cacctgctgc tattggtaat ccaccagatg gaacttcttt gcctgtacac
   105001 gcataaataa gttgtttctc tgctccttgt ggatatttca cttgaaggcc aacaacttcg
   105061 atttcgctat agtctttagc tacattttga attgcttcta tagcatctgg tttattcgtt
   105121 tcaattccta taaatccttt tttgacatct aataccttca ttaatgctct taaaccaaac
   105181 acaacatctt ctggattttc aaccattaat ctgtggtctg cagttaagta tggttcacat
   105241 tctgcaccat ttaatataac tacttctgcc ttgctatctg gtggaggaga tacttttaca
   105301 tggttaggga atgtagctcc acccatacct actattcctg cctcttttat gatacctact
   105361 atatcttctt tgctcaaatc ctctaactga ccttttggtt gaacactctc atgtaattct
   105421 tccttaaagt cattttcgat aactacacat tgagctgaac ctcctggtac ttcatgttgt
   105481 tcaatagcaa taactttacc tgatactgaa gaatgaacgt tacatgaaac aaaaccttgt
   105541 tgttcaccta ttttttgccc aaactttact tcatcaccaa cttcaacaat aggtttagct
   105601 ggtgccccta tatgttgctg aagaggaatg taaactatct ttggagcttg agctttttca
   105661 agtgcctttg tgttagagta ctcttttcta tatggaggat gtatccctcc cttaaaagtt
   105721 aagagtttca ttgttttacc cccttatcta taaaaaaaca ttttttctgc cttctataag
   105781 tatactatat atattaaaaa atcttaacaa ttgttaaaaa aatatccgta tttttataat
   105841 ttattttata aatcaacacc tctatattaa gtcaaattga ggaaaaggat tgcttaatta
   105901 aacaatcctt ttcatatagc tttctaaagt ccaaattttc tgtattttat tttatagaat
   105961 ttataaacat agagtactcc tgcatggatg ataaaagcag acttttactt acactatatt
   106021 tttcttcatt tgctgctttt gaagctgtat caattttttc attcacattc tttacatact
   106081 ctattaaatt atctttaaat aaacgcattt cagaataatc aatcttttca gcttcttttg
   106141 atatattttg tgatattgcc tttctatttg tcaaaatagt attatatttt tccatatcta
   106201 cattattttc agcattcgac caaaaacttg attcttcttt aaagtttgtt attaatttat
   106261 ttaattcttt agatatactc tctatataag cgtagttact tgtatactct aaagacaaca
   106321 taggtgcatc taagtgtgat aaaaatgcat ctggaaacac ctttcttaca ctgcttatct
   106381 gctttctaac atcattttca tcaaaagagg aataggtctg tatttttttt actccatcct
   106441 tctccataac tgaaaaaggt atgtcattat taactaatga tgtctgtatt tttttcaaat
   106501 catcattatt atctattgca gcaacttgaa tagtatacat atcccagcct tctatagtag
   106561 ctaatttgac ttcttctggc tctttagtgt tatttaccgc tttttctgga ttagtttctt
   106621 gtttatcatc tgaattggtt tgtgatttag attttttccc tttttttatt gaatttaatt
   106681 catcagatat atctttataa gttatatctg atgaattatt tagaaatggt attttagccg
   106741 atacatactc caatatcttg ctatctttta tttttgtata agaataatag ccaattagac
   106801 acaagcaagc aatcgttata acatatttac gtaaatcaat cttatgtcta ttattattaa
   106861 atcctctgta tatcgttttt cttctattca ttagtttgtc cctcccaaaa ttatattatt
   106921 aataaagtat atttttaaga gtcacaattt atgaatataa ataattattt cttctaattt
   106981 tttaataaga aattgtactt actaaacaaa tcttcttgca ccaagtaata ctttagacca
   107041 atatgaacta gttaaattat ccactttaac cttattagga ttagtctgag taccactaca
   107101 atggataaat ttactatttc ctacatatat acctacatga ttagttgttc catcaccatc
   107161 agtgtcaaaa taaactaaat ctcctggtgc ataattcccc atagaaattg cacttccaaa
   107221 attagcctgt tctctagaaa ctctaggaat agaaacgcct acagaatgtt taaaaacata
   107281 ctgtgtaaat ccagaacagt caaatttatc aggccctgaa gctccccatt gatatggtat
   107341 tccaataaga gtatatgcaa aatctacgat tgttgaacct tttgctgtag atttatctga
   107401 atttccagta aatgatggct ttgagttact attaggttga gaattttggt tagatgatga
   107461 atttggtttt tcttttgtac cttcattagt ctcagaaata taacttgcac tcacccatcc
   107521 aattgttcca ctcgataact ttaccttata ccaaccatta cttttagctt ttaattcaac
   107581 aacatctcca ccatttaatt ttcctattat agaatagctt gtcccaggac cacttcttac
   107641 atttaaactc acagcagatg ttaccttacc attcttgcct tcaattgatt cttcgctaga
   107701 tggtttttta tcagaattat tagtactatt tgaattacta gaattgttcg ttccaacatc
   107761 ttctgatgtt ttagaaatat attggctact agcccatcca gtaactccat ttgatagttt
   107821 tattttatac catccattgc tttgttctag taactttact acatctccat tatttgcttt
   107881 accaactaat gaatagttag tacctgcacc acttcttaca ttcagtctag aactcacatt
   107941 tactttacca tttccactaa tagttgtccc acttgaagtt ggattatttt gacttgatgt
   108001 accttcagac gaaccacttg ttgatatgta ttttgcactt ccccatccaa caacagaact
   108061 cgataccctt actttatacc atccattaga cttttctaaa atctctacag tttttccctt
   108121 gtataatttt gctaccttat cgcaatcaga acttggtcca cttcttatat tcaaggcact
   108181 tgctgttact gttccctttt caagagcact tgcatttatg gagctaacag atactgctac
   108241 tgccccaatt cctaaagctg ctatagcttt tttcactact atcactcccc ccaacaaatt
   108301 tttatagtca taaattcata acattattat ccatttttag tccctacaat ttaatgataa
   108361 cttattttct tattaattgt aaagaaatta taaacatatc cttaaaatta gtgattttta
   108421 ggaagtattt caatccaata attatctggg tccgctataa aataaattcc catactttca
   108481 ttttcaaaac atatgcaatc taaatcttta tgaagttttt ttgcctcatc aaactcctca
   108541 acttctaaag ccagatgaaa ttcattgtct cctaaattat atggtctatc ccaatctcta
   108601 agccaagtta attctaatgt atgactagta atgccatctc ctaaataaac taatataaaa
   108661 cttccatctt ctgcttcctt gcgctttacc tctttaagcc ctaaagcttt tttataaaaa
   108721 tctaaacttt tttctaaatt agtaacattg aaattgttat gacaaaaatt aaacttcatt
   108781 ttgaaatcac tctccaattt ttattttttt tatattatat cattattata aatttattta
   108841 aatcatatta agttaaaaat ttgaatgatg atgaccaatt accaaatcat ggtaaattat
   108901 ttaaaagaat atgtcaaaaa aagaataagc tctttcaaat gcataaaaaa tttataccca
   108961 agttatactt aatcatgcaa attggcagaa cttattcttt aaaactctaa cttttaagtt
   109021 tttctttaat aatataattt attacttttt ttctaatatc ttcagcatta taatcatctt
   109081 ctacttctat atccaaaagt tttgctattg acctcatatc ttctctagtc tttgacctat
   109141 agcttgatat taattcatct tttattttct ctggttctaa aagatattct tcatctcctc
   109201 ttttgaaaac aacgtatttt tgagcatatg aacttctatt gtagtatata tatcttgata
   109261 tttttcttaa aatttgatta tatgaaagtc gcttgttaat atcaagtttt aagtactctg
   109321 aaaaagcaaa tagctctttt tttgatttaa ataatgcttc tttctttata gttcttgata
   109381 ttgaagttac actttcttga tatgcacact tttttaacat ttttaaatat actctattaa
   109441 gaccaatact ttgattgaat ttttttatat tattattaat aatcttatcc aagttacctt
   109501 caaagtattt ttttgctcct ttttgtgata cataactctc aagttctttg tgggccatat
   109561 caagtatcat tttttttaaa tcctctttat atcccctaga ttccatgata ctccctccct
   109621 tagctattta tagtatattc aaaaagctca agaaatgtga gtcattacaa aattttttta
   109681 ctttttatgt atatattaat ttaaaagggg agataatagt aatgtaaaat caaacatact
   109741 caatctcccc catttttaga cctctattac tcccccaata gaggtctttt tttagtttat
   109801 caatttctat tcaattccct ttagttcaaa tcctaattct gctatcactt cttttaattt
   109861 ttcaatagat acatcatctt tcatatctac agatgcacac ttattttcta aatctacatc
   109921 taaaacttca ataccatcta tatcttctgt taatgcagtt ttaagatggt ttacacaatg
   109981 accacaactc ataccttcta ctaatagttt cttcttcatt taattacctc cttataccct
   110041 ataagggtat tctatcatat agtttatact ttttaaatag aaattaatca tttaatttga
   110101 ttcattcgat tttatatcta aattagatat tccctcatat acatcaaaat catttggagt
   110161 aattttacct tttaatctac tattacttac aatatagttg tttctcacag ctaaacttat
   110221 aaatgttgca ttatctttta tatatgtctg tacatctttg tatgcttttt ttgtttcaat
   110281 ttcagacgta gaacttgtaa gtgcagacat atatccattt aacttatcat cagtatatcc
   110341 actactcgct ataatactac ttgcatctgg tataattgat agtttccatc caactaatgc
   110401 taaatcataa tttttagaat taagagcatt ttccatatcc ttatctgaca gctgatttac
   110461 tgtactattt attcctatag cttttaagtt ttcatttatt atgtttgcag tttttattct
   110521 ctcactatta tctctgttta ctattatctt taagttcatt tcagaaagac ttttctttac
   110581 ttcctctttt tctctatttt ttttctcttc agcttctttt ttgattctat cttcttctgc
   110641 ttttttagct tttgcttctt cttctggcgt aagcttcttt gagttctttt tagctgattt
   110701 tttctgattt tttactttat tgtcattttg atttactgag tttacatttg catattctac
   110761 cttagcaaga cactctatcg ccttatcttt attaaactct aaatccttca tttcactatt
   110821 atagtatttt gattttgaat taagtggaaa attaactgga gtagcatcat ccatataacc
   110881 ttcactaata attctatctt tatctataga gtgtgcaatt gcttttctaa aattaacatc
   110941 tttgaaaaaa ggattattat aattaaataa tacacactca taatctcttc cttgatattt
   111001 tgttatatta aactcttttt cttgaaactt acttaaatca tttaatgtaa cattggttat
   111061 atcactatca agagccataa ccatagatgt ccttgcatct tcattaggca ccatacctac
   111121 ttttatgttc ttcatggttt ttggaacttc ttcatagtaa tctttgttta cagataaaac
   111181 cattccttct ctttctgtat atgattctat tttatatttc ccatttccta tcatattatt
   111241 attcttgtca tttacatctt ttgaatctaa atgattttga gatacaattg gaaaaattaa
   111301 actatcaatt gaaaaagcat atctagcttt aaattttatt gtaaaatctt tatctgattt
   111361 aatattcaca gaagctatat ttttagtaaa ttcattatat ggactatctg cacttttttg
   111421 aattaaacca atagtatagt ttacatcatt tgaagtaaca ttttttccat catgccactt
   111481 tgcatctttt agctttatat ctatactcat tccatcctga gctatattat actccttaac
   111541 taattgagga attacattgt agttctcatc tatagtaaat aaactatcat aaactaaatt
   111601 cattatataa ccaacagact tatcagtatt agttatagga tttatagttt ttggagttac
   111661 cattgttaag tttatatact tagcatctat agaactttga ctttgtaaac ttgaatcact
   111721 actactttgt tttgttttag tattactaca accagctacc ataagagtta tagctaaaac
   111781 gactgttaag acttttattc tcttcattag ttttttcctt tcttgccata tatcttatta
   111841 taatgttcgt aattattttt tactttttct acatattttg aagtttgctt aaaaggtata
   111901 tcatgtagat tttcgccatc tttactatat tcattatttt ctaaccattt tttcacatta
   111961 cctgaaccac cattatatgc agctatcact aaatctaatt taccaaattc tttgtataac
   112021 ttacttaaat accaacagcc aagtcttata ttagtctctg ggtcgaaaat atccacattt
   112081 tttaaattta gttcctctgc tccccaatct ctagttatgt ctaatatttg cattaatcct
   112141 tttgcttcct tttttgaaac agcagaacta ttaaacttac tttcggcttt aataacactg
   112201 taaactatat tttcatctaa attaaattct ttcgaatact tttctacata ctctgaatat
   112261 tttttaggat ataaaaattt atgtattact ttgctttcca ttaatagtgc cccaaataag
   112321 attataaaaa tagatagaat caatactttc ttactattca cgccaattct ccttcatgta
   112381 ctcaataaat ttatgtgctt tactttctaa ttcagttatt gttcccgaat tatctattat
   112441 ataatcacca tatttggatt tttcttcctg actcatctgt gaatttatcc tactaagtgc
   112501 ttcctgctca ctgcaattat ctctcttttg tattctacta atttgtactt cttgtttaca
   112561 agtaactact aatagcttgt caaccatatc taaaaaacca ctttctacca atattgccgc
   112621 atctaacact actatatttt cgcctttttt tctcaatttt tctatttcac ttattatttt
   112681 ttctcttatt cgtggatgag tcaagttatt taattcctta agtttttctt catcactaaa
   112741 aactattttc ccaagagctt ttctatttag agttccatca tcatttttta tactttgccc
   112801 aaaatggaca aatacttttt ccaataacaa cttatcctca aatatcttcc tggatataat
   112861 atcagcatcc actataggaa tgttaagatt tctaaatata tttgataggc tgctttttcc
   112921 acagcctatt cctcctgtaa gtcctaatat caacataaaa tcacctactt tgtctcatac
   112981 caagaactac ctacatttaa atctacatct aagtgaacat ccatatttac agcattttcc
   113041 atttcttctt ttactatttt cttaactata tctatttcat catcaattgc ttcaactatc
   113101 aactcgtcgt gaacttgtag tataagtttt gatttcaaat tgttctcttc caatttttta
   113161 tgaacattta tcatagcaat ttttattata tctgctgcac ttccttgtat tggtgcattc
   113221 attgcaaatc tctttcctct atttctttcc ataaaattgc ttgactttat ttctggtata
   113281 tatcttcttc tgtttaaaat tgttacagca tatccatcct cactagcctt ttctactgtt
   113341 gtgtccataa actcttttat tttatggtat ttagcaaaat aactttcgat atattctttc
   113401 gcctttggaa caggtatatt taaatcatca gctagaccaa agtcactttt accatatata
   113461 ataccaaagt ttacagcttt agctgcacct ctcaattcac tagtaacatc ttccatagga
   113521 acattaaaaa cttgtgaagc tgttttggta tgaatatctt catgatgttt aaatgcttct
   113581 atcatatttt catcctgact catatgtgca agaactctta gctctacttg tgagtaatcg
   113641 gcatcaacca acttacagtt atcatctgca ataaacactt ttcttatttt tctacccatt
   113701 tccattttta taggtatatt ttgaagattt ggttctgtag atgaaattct tcctgtagtc
   113761 gttatagttt gattaaatga tgaatgtatt ctattacttt ctggatttat tatatttaaa
   113821 agtccttcaa cgtaagtaga atttaacttt actatttgtc tatactcagt tatcttatct
   113881 attattggat gcttatctct taatttttct aaaacatctg cattagttga atatccagtt
   113941 ttagtttttt taattattgg aagctctaat ttttcaaata atataacacc caattgtttt
   114001 ggtgaattta tattgaatgg ctctcctgat aattcataaa tttccttttc taatgtagct
   114061 attatttctt taaactctac actcaattca tccaatatac ttttgtctac ttttatacct
   114121 tcatactcca tatgacctaa gacttctact aaaggcatct ctacatgata aaaaagacca
   114181 tccatactca tatccattag acttctttcc atcataggaa ctgtttcttt aactgtgcat
   114241 attatttgac ccatatactc tgctaaatcc tcaaattcta aatcctcata gtttttagat
   114301 ttaacaccct ttcctaataa ttcttctttt gatttaacct tttttgataa atacttcata
   114361 gctattgcac tacaatcata tgaggtagat gaagttgaat ctattaagta ctcagctatt
   114421 gttatatcaa aatacatatt ttctaagttt atattatatg gttttaaaga tatataatca
   114481 tcttttaaat tatatccata ctttttaatt tcattatttg aaaatatact atctaacttt
   114541 gacacttcat ttgaatctac ataatatatt ttttctccat ctacacttat aaaaatatat
   114601 attatatttt tttcaagtat attaccttgt cctctaacag tttttaaaat aacttgtcct
   114661 tttttgttta cttcatctat aaatttttct atatctttta attttaatat ttctattttt
   114721 tcttctacgt gttctgtgtc atctgaatcg accaaatcaa ctaatcttga taagagactt
   114781 gtaaatccaa agtatctaaa tttatctaaa agttcatctt tatcataatc gccaaaaatc
   114841 atactatcta aatccacttc tattggcaca tctcttataa ttgttgcaag tcttttactt
   114901 tgaatagcta tttctttgtt ttcctctatt ttctttttta cactaccttt aagcttatct
   114961 gtattctcta ttagattctc tatactagaa aactctttta taagctttat acctgttttt
   115021 tcacctattc caggtactcc aggtatatta tcagacttgt ctcccataag accctttaaa
   115081 tcgataaatt gtgttggagt catctcatat ttttcaatta cagaattaaa gttgtattct
   115141 tctacttctc caaccccttt tttcgttata agggtagttg tattatctga agcaagttga
   115201 atagcatctt tatctccagt tactatgtat accttatatc cattttcttc tgctttttta
   115261 gaaacagttc ctataatgtc gtctgcctca tagccatcta tttccaatct atttattttg
   115321 aatttatcta aaaggtcttt taatggctgt aattgttctg ccagttcatc tggcattccc
   115381 tttcttccag ccttatactc tttatattct aaatgtctaa atgtaggtgc ttttctgtca
   115441 aatgctacac ttatatgtgt tggtttatat atatctatca ttttaaatag cattgttgta
   115501 aatccatata ttgcattggt ctttagccct tctttattat tcatttctgg aagagcataa
   115561 aaagctctat ttattattga atttccatct attataatta attttttttc caaattatat
   115621 cactcctaaa aattatctat ttttgtaaca tatatattat ataccaatat actgttattt
   115681 aatattccca taataataat agtatattaa aattaaatat gttgcaaaca atatattttt
   115741 ttgctataat aatatacatg acatgcccga gtggtggaat tggtagacgc agtggactca
   115801 aaatccaccg gactaatact ccgtgccggt tcgagtccgg cctcgggcac cattaaaaac
   115861 tcctaaagct atttattcaa tagattagga gtttttttat ttttgattta aattttaagt
   115921 tattttttga aattactgtg tctttttaaa atttatataa ttatataaat ttatcttcta
   115981 gcattaattt aaaaactaat ttatttttat ataattttct attttatatc ataacttatt
   116041 acaacttttt atctaattta ttgtatacaa caacactaca aataaattga aataaaataa
   116101 gcaatccaag aacaactaaa acccacttgc ttattaccat tacagaaaat acactcaata
   116161 tagaaacaat aaatataaga attacaagaa cataggacat gatttgatta gtgatacgtc
   116221 cagctttatc acgtaacata attcttcttt catcattcat ctctatcctt tgatttttta
   116281 tcttttcttc ataatctact gctctttcag gtttactcca atacatatat tgaagaatca
   116341 tacatacacc tggacctaaa gcagctccag ataatcccca aataaaagcc tcaaatgaaa
   116401 actcagtaaa tgtagccaat aaaacaagta aaattccaca aataaaatat ataattccaa
   116461 catataacat attctttttc atttttactc ctcctcataa ataaatattt cttcaatact
   116521 catatcaaag tatctagcta tcttaaaggc taagatgata gaaggattat acctaccatt
   116581 ttctaatgaa cctatagttt gtcttgatac ttgcaaaata gaagcaagtt cttcttgttt
   116641 tatgcctctt tcttttctta tttcttctaa tctatttttc acatctatcc ccctttaata
   116701 tctcaactac ggaaagtcta ctttccataa ttatacaact atattccatt tatgtaaagc
   116761 ttactttcca tatttacaaa aaaataacag actattttca gcctgtaatt ttagaatttc
   116821 atgttgttta ttaattttaa tgttatttat taattccata ttatttatta attttaactt
   116881 ggtttctgaa ttggaatcca aacttctgta gtataatcag gagcattgat atcgccattg
   116941 ggataaagtt caatatctgg taaattagca tacacatacc cagaacttgg taaccactca
   117001 gtaataattc ttttttgcaa ttcctgtatt gccagagcat ttggcattgg agaaacacat
   117061 tcaaatactg cccatgtgcc tgatggtatt aagtattcat gagtatcttc taatacaggc
   117121 ttatctgttg gagcagcaat ataataatct aaacccttac tatttgtaca cacactaact
   117181 ccaagcaatc cacaaggttc attatttatt aactctgaaa gtttatcaat tgttccattt
   117241 tttatgcatt tagcccacaa cttaggaact ttctcaaagc actcttctac aatcatgttc
   117301 atactttctt ttataccaac aatacgaaac cctttctttt ctacaatacg atattgcatt
   117361 tctatatttc cttttacata aatgcttaat gtcatcttag gatatgcttt taaaacaaca
   117421 ccctttgctc tagctgcaga tggagaaatg ttatgtatat tttgaaaagc tctattaaaa
   117481 gatgttggtg aatcgtaacc atacttctca gatagttcta aaattttgat gttactgttc
   117541 tgaagttcaa atgcagcctt agtcatacgt cttcgtctaa tatattcaga taatggtact
   117601 tctgcaatat atgaaaacat tctttgaaaa tgaaaggttg aacaacatgc aatttttgct
   117661 gcttctgcat aatccactcc actttcgaga ttttcttcaa tataagtaat agcttgattt
   117721 aatttattta tccattccat ttgatattac ctccaagcaa attatacagt ttaataaaat
   117781 aatatacctc tctattcatg cacaaaattg taagcattta aattcataag tatttttcaa
   117841 tcaatacaat aaatataaaa attgtattat acaataaaaa agttcaataa cattatatta
   117901 taaaatgtta ttgaactttt tataaaaatt aatttaagtg tagttaaatt aagtattaca
   117961 ctatcttata tattacaata tcctactatc ttatagtctt ctggcacttt ataatctttg
   118021 tctggagtac ctaaattcca ttttaaatca aacatagttg cacttattat tgttgcaaaa
   118081 taaagcataa ctataccaat gtctattttt tcttcatata aattagtatg accatctttt
   118141 ctaacagcta aaactacagt gcctccatca actataaatc tccatggttg tctatttaat
   118201 gtagatggag ctaatcttgc atagtgaaat gcatcaagaa gtgctctttc ttctaagatt
   118261 tctatacttg caacatttcc ccattcgttc atataaacaa catcttctac acctagtcta
   118321 gtagacccct tatctgttac aacttgcata tcagattttg aataattttg cccagttttt
   118381 gtagcattta atactttagc attacttaca ttttctccat atccaatagc tataattcct
   118441 gttacctctt tatctgaatt aattccaagt ttttctttta ccttttttcc atcttcaaaa
   118501 gtaacccaac aagaaccaat tccaagttct gttactttaa agattatact ttctcctatg
   118561 taccctgaat tttcaatgta attatctttt atgtcagata atattataat ataacttgga
   118621 gaatctatca tatttccttt gtaccctgct actttatcta aattattaaa aacttcactt
   118681 ctattcataa ttcttacatc aacatctatt tctggaacta gtttcttaca agattctgag
   118741 tatttcttaa tttcactaag atattcttct ttaatatctg tgttcttata ttctctaaca
   118801 gactttctat ttaatatgat tgttttataa tccataattt tatcctcccc aaactagtat
   118861 tgtcttaatt atatacccat taatatatta ttttactcat ttatttaata aataaagatt
   118921 acaattttgt aattattatt tattaataat attccacttt tacattaata atgaccagtt
   118981 gtgcaaaatc cattgccaac caccaaataa aaacatatta taaaggtaat ataaaataac
   119041 aaacaaatct taacaaaaaa ttaaactttt tttacacgaa agaaggcttc ccgttgcctt
   119101 ctttattttt ataaaaaaat aagctgtttc taaaatgatt tcacattttt gaaacagcca
   119161 agttattcta taatgacaac tataatttga ggatgtgagg gagagttgtc attataaatt
   119221 tagggtaatt atattatgtt ttaagctagt tctttctata tttatataat acattttata
   119281 tatgaatttt atatgagatt ggtataaatg atatatgaaa ttacatatgt ttatattata
   119341 ttaaatttta ttattacatt ttccacaaca atactcatat gtctccacat tatttggaat
   119401 atttacaaat acaaattctt tacagttctc acaatacttt aatatagata tagttccaca
   119461 agtgtaacat tcaaatatta cacaatcctc attttcctct actatttcaa actttttact
   119521 atgttcacca cactctgggc acttgtgatt atttacattc ataaatactc ctccttatta
   119581 gtatagttac atgtcaaaaa cttaattaat gtattctata ttacttatta tatattctat
   119641 aataaatcat attctaatat aataaaacaa attaaataaa aaaaaaccat aaattttaaa
   119701 tttatggatt aattcttgta atgataactc tatttgagga tgtgagggag ggttatcatt
   119761 acaatagggt attatattat ggtttttaag ctagtctttc tacacctcat atgatacata
   119821 tgctatatga attttatatg atttttacat aaatatttta tgaaatttaa attttttagt
   119881 cattttgaaa tttgtaaaaa gttctctaaa aatccacagc atcataaaca gccaaaattt
   119941 aagtaaaaca tcataaaaaa atttgtccaa taattttaac aagtaatctc acctcattat
   120001 aattattgac acaaacttaa ataaacaatc tataaatctt ctataaatct taaactttcc
   120061 ccctattgat acacaatttc tagtttgtca attttatttt gcatttctaa gaaaatttct
   120121 tcaacagaat tgttaaatat attgcctaaa tagattcttt tatctttttg aaatgaataa
   120181 gattttacac taccatcaga agaaatatat aaatgactcc actctgctcc atattttgaa
   120241 aacctctcct ttgtatcttt aaacctcata tcttctattt ttattgcttt ttctctgtct
   120301 cctcttacta cagtgtgacc cctttttatt aaactggtta tttttatatc ttcttttaat
   120361 ttaatacgtg tatcatcatt ttttgaatat actttccata tcactttatg acgataatta
   120421 tctaattcct ttattaagct tctatcaata gtaaaactat ctttagttac cacaattaaa
   120481 tcaaaatggt ctaacatata ttgaaatatt tctctcatac ttttattttt taaaatatcc
   120541 tcaccaataa cctctataaa tctacagcct ttctcataca tgcagttcaa taaacttgtg
   120601 atttcagaaa aataatcatt tgtattatta tctccatcta tttctatagt aaagtacaaa
   120661 ggagtaatgt atgatttatt tcctgttatc tcaaatacac ttgatagtgt ctgtatatca
   120721 tcttcaaacg ttaagtatac attctcataa aacataaaaa attccataac tttttctttc
   120781 atattatgga tatttctata tctattggat aatatattta ttatatcgtc agtagtattt
   120841 ttcccatcac attcagccag tataacaatt tgcttccaac ttaagctatc cacatttccg
   120901 atactttttt tatatccatc ttcttcatca taaatagggc caattataat gttttctttt
   120961 ggccacagat gaaccctagt tccatctttt aatttcggat atttattttt tacagactca
   121021 taaaatctac ttgtatcacc catgattctt tactaccccc catagtttaa atattctatg
   121081 ctaaaaatag cactttattt ttattaattc aacaattatt caaaattggt cattatatat
   121141 gtttaaatgg atttaacatc aaccttattt atatgttatt gatgtttata tatgttatat
   121201 aaaatcttat ttctcatact tcaatgtaat cttaactatc tctggtttac aattgagcct
   121261 aattaaaact tttgagcctc ctaagccttt atttaaaatc atagtgctat tatctttttc
   121321 atattttccc cagtcatact taggaaagaa ctctctattt ggagataata cacctccaac
   121381 aaaaggtatt cttattatac ctccatgaac atgtcctgct aaaaccaaat ctgctcccca
   121441 ttttgcatat ttttcaaaga aaaatggtgt atgtgctaaa agaatgttat attcattttc
   121501 attaacttta cctagattgt cttctacaaa attgtcactt agttctaatt ttttgttatt
   121561 agcaaataaa tatggatagc attccaatgg tataattaaa ccatataaat taagatggct
   121621 attacctcta tatattctta cagattcatt ttccatattt attattttct ttgaatatag
   121681 ttccttaaaa taatccttat atagatgttt atactttttt attaaagatt tttgttcatg
   121741 atttccaatt atatgatata cttcatattt ttcaaccaaa ttatctatta aatctaatgc
   121801 aacttgaaaa tttttatttt ctccatctac taaatctcct gttataaata taacatctgg
   121861 gtttaatgat tcaattttat ctatcaatac cttattattt ttatcaaaca ccttattatg
   121921 taaatcactc acttgaacta ttttaaagtt atcaaattcc tttggaattt ttttgttgaa
   121981 aatagtatat tctgtcgttt ctatatgctg agtttcatac ttatacagaa tatacaataa
   122041 tattaatact aatactgtca ttgaaacctt tataatcata ttctcttcct ctttattcta
   122101 ttttgttaat attattataa tgcttttatg ttttttttaa aacaataaca tcatcacata
   122161 catataaatc ttttcgacat tataaaaata agttatcctt ttctaaaatt ttcatttatt
   122221 ttagaaaagg ataactataa aattatctat aaacctctat attgtgaaat atagtttttc
   122281 ctttatttaa atttttatat atatgctcta aagttccatc aaacctaata gaatgtccag
   122341 actctaaaat ataagttttc ccatccacat taaggtcaag tttaccttct attacgagca
   122401 catattcttc taaaacatga ctatgtgtag atgaaacatg agtacagttt tcctcaagct
   122461 caattataaa aagttcaaac cttctttgag ggctaaaagg gtatattgga tataacttca
   122521 tgttcccttt ttgctcaaca ataggctcta cttcttcttt ctttataacc tcataggtat
   122581 ttgtattttc atttaatagt gtagtaaaat ttattttaaa tccagatgaa attttccata
   122641 aagtagatac tgtcggactt gattcacctc tctcaatctg tccaagcatt gctttactga
   122701 cacctgtcat ctttgaagct ttgtctaaac ttatgcccat ttcttgtctc aataacctta
   122761 aattttctcc cacattagga aatttattat ccatgttaaa atcctcctga tagctatttg
   122821 tattctatga tttttactcc tgtaagttct actatctctt ttaattttaa catatgattg
   122881 ttacaaattt catcaaattc atatatataa tcttcaagcc ctaatgcctt atatttatcg
   122941 attccaaatt tatgatatgg aagtaactcc atcttgcctc ctggaacatt ttgtttaaca
   123001 aataatgcag tatttcttat attttcttca ctatcattta ctccataaat aattggcact
   123061 cttataacca tagatttatt caactttgaa agcctacata tattatctaa tataatttta
   123121 ttacttactc ctgtatattc tttatgaata ttatcatcca tagattttat atctacaaat
   123181 atgtggtcta ttttctcaaa tacatcattt accttattcc aatcaaaata tccacaagtt
   123241 tcaattgcaa tatttatgcc tttatcataa aaaatatcaa ctaattctct taaaaaatca
   123301 atctgaagtg taggttcacc tccagaaaaa gttatccctc cattagattc aaagaaaaat
   123361 ataaaatctt tttcaacttc ctctactatt tcttcaacac tcatttcttc ggtcattata
   123421 caaatggcat ctttaagaca taccttgata cactctccac ataaatcaca tttattattt
   123481 atttgcgttc tatcaaatag tgaacttata ttttgaggac aaacatctat acatctatta
   123541 caggatacac atttatcttt cataacacct aattttacta tgttactcca ggaatctgga
   123601 ttagaacacc acttacattt taatttacat ccttctaaaa atatagtagt ccttattcca
   123661 tctccatcat ttactgaaaa atgttgtact tttacaactc tacctttttt actcataatc
   123721 tacctcataa ttaaaaattg ctatgtgaat ttctagctat tatagcatct tgcatttctc
   123781 ttgataaatt aacaaattga gtactatatc cagcaaccct cactaataaa tctttatatt
   123841 cttctggatt ttcttgagct tttaatagag tatcatttga tatcgtatta aattgtacat
   123901 ggaatcctcc taaagcaaaa tatgatttaa tcatagatgt tagatttcta agtcctcttt
   123961 cagtttccac caaatcttga ttcagtctta aatttagaag tgttccacca gtatgaacat
   124021 catgatttat ttttgatgca gatttcattg ctgctagtgg acttgttgta tcagtaccaa
   124081 caaatggaga aactccctct gtcaaaggtt ttgtcgcttt tcttccacaa ggagttgcac
   124141 ctactatttt tccagttggt acatagtttg atatacccat aaatgcacta ttaaatttag
   124201 agccaaaaat atccttgtat tttctagttt cagtataata aaaatcagaa acttcaattg
   124261 ctaatgaatc tacataatca ttatcatttc catacttagg aacatccaac gcaagttttc
   124321 ttaattcttc ataaccttcc caatcattat ttagtgcttt tgttaattct tctaacgtag
   124381 tcaccttatc ctcaaatact aattttttta tagctgccaa tgaatttgaa actacaccta
   124441 accctatacc agttaataca ggacctatat tatattttgc tcctccttta cttaaatcaa
   124501 ctcccttatc caaacatcca tctacacaag tagataaaaa tggtcttggt accatttctt
   124561 tatgaatttg ttgagcaaca gtagttccta taacagaact ttttacaaga tatgctaatt
   124621 gctttaaaaa ctcatcctta agttcttcaa aagaagtaaa ttctgtgata ttttttgtat
   124681 ctaaccccat tttttctcca gttaatctac tcttaccttc attcatagca tattctaaag
   124741 ctgctgcaaa attgatattt acggctgaag tccactgtcc tgtttttcta aaatgaggaa
   124801 ctacacaacc acagttactc caatctctag catcttctgc atcatatcca tcttgtaata
   124861 acatttgtgc ccctgcacta tcgctgtgta tagcagggaa accagttcct tgttttacca
   124921 atttagcaac tgccattacg aaattatctg gtgctccttg actcactcta acacttaatc
   124981 ctggctggtg agtttttaca ctttctgtag cctttaaaca catatatgag atatcattcg
   125041 ttccatcagt accatttctc tttttaccac caacagtaag attttggaat tgattatatc
   125101 ctgcaaagta atttgctgta tttgctgata tagtccatac ccattctgat aacttaatcc
   125161 aaagtgcttc tatcaattct tgagcttctg attcagttat tttaccttct ctagcatcat
   125221 tttcataata tggatacata tattggtcaa atctacctaa atttaatgcc aatggatttt
   125281 ctgatagaat accacctaat tgaacaaacc atacaaattg tattgcttca taaaaattag
   125341 ttggagggtt tgctggtaca ttcatacata tctctgaaat ttttataagt tctaactttc
   125401 tcttttcatc tgtttcttgc ttactcatct cttttgcaag atttgaatat ctttgtgcca
   125461 atgtcataat accctgtgca actatagaaa cagatttgta aaaatctatc ttttcaatat
   125521 tttctgaaac tgatatatct aattctttaa tttttttatc tgcatcttcc ttaatccctt
   125581 tatatccttt tacaaacaat atatcttgat aatctggtgt tacttcacca actgcctgtc
   125641 tccacttaga atcattatct attattcctg tatctactaa tatcttagct gtatcttctg
   125701 ggattcttgc taagaaaact tcttccaaag attttccctt ccaatatgga aatatttctt
   125761 ttcttataaa ttctatttgt tcttttgata ttacatatgg gtcttgagtt cttttatcaa
   125821 aagtatccat ttctttgtct acccattgcc aagaaaactc tggtgtcaat atccctgttc
   125881 ttctaaattt tcctgctgta cctactatta attcattttc aaagattttt ataggaagtt
   125941 ctttacatgt ctccaaaaaa gctttagctc ttcttataca gatagcttct ccctcagttt
   126001 ttttatgtga ttctgtaaaa attctagccc tttcacaaca tatcataggt ttagaattaa
   126061 tatattcttg tctaaatgct tctattctat tagtttgact catttaaaat ccccctttgg
   126121 ataatatata ctacattttt gtatgttata acatacttta attatattat actgtccttt
   126181 agcataaaat ggaagcaaaa taacttattt tttttcatct accttgaaca cctatatatt
   126241 aatacttttt ttgttaaatt tataaaatct aaaaaaattt tctatgatat attttctata
   126301 ttgttatagt tatttctaat atactaatga tttgaaatat caaatttgta tactagactt
   126361 agttttaaaa ccttagttga ttgtttaact ttgttaactt caacatgtat atccttcata
   126421 taaggaagct ctacaacacc tactccctta ttaaagtctt cttcaaccat agaaaaaatt
   126481 tctttctcag ttaagttcgt attagtcaat gatttaaata aattataata aatcatatat
   126541 gtctttttga ctatcttttt atatcttctt aaatgtccgc aaagccttat tttataggct
   126601 ctacgggcat tttgcttttg tggtaaacct cacatatcta ggtctatctt cttatatttt
   126661 cgctatcaag cgtggttaaa atcgtggtaa atacttctta tgcgattaga cgctgaacct
   126721 ctgattttgc ggtatctatg gacgcatgag cataccagtt cattgtgata ctgatgtttg
   126781 aatgtcccat gatatactgt aaatctttcg ggttcatgtt cttgcttgcc agtcttgtgc
   126841 agaacgtatg gcgtagcgta tgtggtgtga tatgtggcaa ggggttatcc ttgtggtgtt
   126901 tgttatattt ctttaccata cggacaaata aggcgttgta atcaatcgca actttaggat
   126961 tgcctttcgg attgacgaac agaaaatctt tgtatccgtc tatctctatc agtttccctt
   127021 ttgtgcgttt ccttatgacc cgttgaaatg cctgtatcgt ttctctgctt aatggcactt
   127081 gccttgttcc actctttgtc ttaggcgttt caatataata gccctgttcc ttgctcttta
   127141 ataactggtg gtcgataacc acaacctcat tcttgaaatc aatatcggct actgtcagtc
   127201 cgcacagttc cgagatacga agtcctgtct ttaacagtat cagcacatca tcataatact
   127261 tgtgatacac gttatccgtc ttgatgaatg acagtaaggc ttgttcctgt tcctctgtca
   127321 atgctacttt ctctttggta tcattttcta tgatttcact taacttgaaa ttaaaagggt
   127381 ttttccttac acaatcgtct tgtatggcga tatagaatga cgcttttaac gagcgtttat
   127441 ggttgttaat agtgttatag gaaaagcctt tgtctttcat gcgtaacgcc cattctttag
   127501 cgtcagaggg ttttatcgta tcaatgctcc tagcacctaa cttgtcctct ttcaataacc
   127561 gcatgagttg ttcccgttgt ttctgtgtgc ttttcttcac atttgccctc tgtgcgttct
   127621 gtttggcgta gagttggcaa agcgtcattt tcttgcctgt gctgtcgata ccgtcctcaa
   127681 tatcccgtct tatctgctgt tccagttcac gaagtgaggg tttttcccgt tttccctttg
   127741 gtgtcgggtc tgtgggtgtc aatctccaag catacacata ttttgtgttt ccaaatgcgt
   127801 ctacatattt atataagtat tttccgtctg ttcgttggct ctctccagta tgcaggatac
   127861 gttctttact atcccgtctt ttttctttca tggtgtctgc tcctttcctt gttggaaaga
   127921 gccttgatat gacttgtgtt catcataaca catacaaggc tcatttgcat tagattgcgt
   127981 ccaatttatc aatgaccttt tcaaactgtc ggcgtttaat ctgtatgcgg ttgccattca
   128041 taatgagcca gccagcgtcc ttgttttcct ctgccaagcg tcttaacttg ttttctccga
   128101 tacggaaata ctttgacgct tcttcaatgg taagggtgta tttttcccat acgggaatat
   128161 cgttgttatt catcagatac cccctttccc atgtttcgtg tcatactgga tataggggat
   128221 aaggtcggtg cggtctatcc tctgtaagtg ggcggttaat ttactggaaa gggaactgct
   128281 gtatcttgcc ctgtcaagca tagttcccac tttttccagt ccacctaatg catcatgttc
   128341 ttctaagaaa taaaaacttt tgacagcaga aatcacgcca ccctctgtga gccattgctg
   128401 tgtttcctca agggaattat gtagtttcgg tacttgcagt ttcaagactt ccacagcccc
   128461 taaaaatcgt tcccaaaacc gacacgtttt ccatctgctc ttattacttt catttctgtt
   128521 tggcacgaca aagcgtaggt tgtttgctaa tagcccgaaa gccagttccc caagttccag
   128581 cggtctgtct ttgaatgtca tggcaaaaac atgagcctta tcatcacgca gttgcatttc
   128641 tgtccgtttc caactgccga cttcatcaag tgtcttatta tgttttgaac agacttcctt
   128701 atccttatca taaaagcggt aggataatcc cgatttacca gcaccgatat aaacagtctt
   128761 tgcggtgtcg aaatcatcaa acttgctttc gtcaaagtgg tagccctcac tattagaaat
   128821 aaattcctct ttttcgcatt tcttctttat ctgctctatg gtaaagaatg gcttttcgtt
   128881 cttatcatca atggcaatat caagtcttgt gaaatgaaag ttatccagtc cgtatcttcg
   128941 ctcacagcgt cgaaacatat ccccaaaggt ataattccta ctgtcgagaa tacggaaaat
   129001 atcatcacaa cctctgccag tcataacaag ataacagcct agcccctgtg ggttatcctc
   129061 tgtctttctt gcgtcccccg atacataaat atctccaatc tgccagcgtg cttgataagt
   129121 cttgaatttt atcattgctg gataaacatt gaaaatgtca gtcggtaaat ctaaaatgtg
   129181 catgattaca tcttcagcgg ttgccgtttc aaatacaatg ctgatgtaat caatcttaac
   129241 ggataaattt ttgtgtgtag ttatagtgca ttgctccttt cgtatgcccc gttttttgcg
   129301 gggtaaaaat cgtgtttttt cctttattta tcacagtttc taggtactat gacatgtata
   129361 cgcagggcgg tgttacatat acgcccttta cgaacgccta aaggcgttcc ctttccaaaa
   129421 ggaactgtct gtccgaaaca cgtctggggg acgtgccccg tccagccagc cccttttgga
   129481 aaccactatt ttctgtctga tagtccatgc ccattcatgc tatcaaaatg aaaatacatc
   129541 ttttctatgc ttactcaagc gtgtgattga ccctagcgtg cttaatcact ctatctgata
   129601 cgataataac gccattagaa ttacttgtca agaagttttt gttgactttt tgatatttat
   129661 taagtatgat atgcttataa ataccgagaa aagcaatgaa aggagtgttt atactaagtt
   129721 atggagcatt atgaaaagaa aatcagtttc ttaggagaga acatacagac cataagaaag
   129781 cacagaggaa tgaaacaaca agaacttgcg gacaaaatcg gtatcaatat gcagagcctt
   129841 tccaagattg aacgtggcgt gaattatcct acctttgata cgctggaaaa aattatggac
   129901 gtgctgggtg taacgccaaa tgaattgcta tcgggggaat ggaagtttgt cagtcaaggc
   129961 gaaaaggaag tctgccagtt tctaagaacg gaagaacgcc taaaagcaga gttgaaacat
   130021 ggacactatg acaacttctt tgacagtgag gaagaatggc tggaatatga gttagaaaag
   130081 ttacgggaat acattatcga ctacatcaac ggaaagagca ttgaagcgtc cgacctttac
   130141 ccaatcaaag aatttatcca gcatttgaaa ttccaaaaag tgttagaccg ctatgatgat
   130201 ttgtacagca tggacatgtt tggggaaagc acagatggac acaagtacgg aacaccttat
   130261 caagttgtga agatgataaa ccccaactca aaagaagata tggaactgtt acgggaagta
   130321 ttaaaggata gccgttttga tgatgaggac gagtaacctt tttcctcttg cgagaagata
   130381 cagaaaacaa aaagcccgat caagagtgca aagcaccacc tatggtggca ggctcttgac
   130441 aggacttttt cttttctgtg ttagataatc aagaggaaga aaggcaaagt gtaccttttt
   130501 aaaggagaaa aatggcaaag gtatgatgat ttttgttgtg gcagatatat ggaactggta
   130561 taatatggac atgaaatata caaataaatc tgttgaaaaa tgaggtatca aaatatgggg
   130621 aatgaattac tggaaaactt agatagactt cacacaactg aacttggcgt tattagaatt
   130681 aaaaagaact tatctctgaa tgtagaaaat gtgattgaat ggtgcaaaga aaaaattagc
   130741 ctttcttatg cggaaatcac aagaaaagga aaaaactggt atataacgat tgataattgt
   130801 attattacgg taaataagta cagttatacc gttatcactg ctcataaaat aaaatgataa
   130861 ttttttctat aaaggaatta aacacatttt cggttatcgg gcaggaaata gaacttacta
   130921 attatcaaaa aaagaatatt cagattagta cacagttttg gagaaagttt aacaaaaatc
   130981 gtatctttca caatcgagaa attaggtaaa atatgctttt atggaaagaa gaaatggaaa
   131041 actttattat ttctgttcta ttccaaagcg aaccattatt ccagagagct ttctgtataa
   131101 agaaataccg tcttataaat atttggttgt ggagcatatt ggtgctatgg ataaaatata
   131161 tgaaacttat ggaaagattt atcaagaaat tattcctagt acaccgtata ttcctataaa
   131221 agatattatc ctacactttg aaaaatatga ttaccgtttt cattggaata gagataattc
   131281 agttattgga atttggatac ctatttaaga ttaaaaacaa ttttgtatcc atacatacaa
   131341 agcagtcaat tctaagacta attgctttat gtatatagat atgaaattga caaactggac
   131401 ttatcgttct gacatatatt cctgtatttc atcagaagtc aattttcgta tttgtgtatt
   131461 tgcatattct ttatattttt caacagcaaa aacaggtttc gtatctttac aggttttacc
   131521 tttattcttt ttcagatata actgcaagtc ctcattattt gcaaaaattt tataggaaag
   131581 tctcccattt tcactttcta tttcataaat accacaggac tttttctaag tttcgcgtta
   131641 tagctttcgt ttcaaagata gatatcccgt ttcgatttgt acgtgctttt ttatactctc
   131701 ttttctgtat ttctaataaa accatgacat tgtgtgacat ggtttttgtg ttatactgat
   131761 atacatggag gtgtcactta tgcaggaaag tcgattattt aaaattgtat attatttgct
   131821 tgataaaggg aaagccacag ctccagagtt ggcagaaaag tttgaggttt cggttagaac
   131881 aatttttaga gatattgatg cccttagcgg agcaggtatt ccaatctatg cggaaacagg
   131941 gtgtaaaggt ggcatttgtt taatgaatga ttttgtttta gacaaagcag ttttgtccga
   132001 aaaagaaaag caagagatat tagcagcgtt acaaagtttg tccgtaatag gaaatgtcta
   132061 tgaggatgct acgcttgtaa agttgtctgc actttttaat actcgttctg aaacatggtt
   132121 tgaggtagat ttttcaaggt gggaaaccaa aacagaagat aatgaaaaat ttgaaacgct
   132181 aaaaacggcg gtcatccatc ataaatctgc ggaaatttcc tatgcaagtg gcgatggcca
   132241 gtacagcaaa agaaaagtac aaccgctaaa attgtactac aaaacaaatg catggtattt
   132301 aaaagcattt tgcaccgaaa gacatgactt tcgtatgttt aagctaaatc ggattttaag
   132361 tattaaactt ttgaacgagg attttatccc cacatcattc ccggaagttc agaaaatgcc
   132421 gtcacagact tatgggaaag ctgttcttcg cttttccaaa gaagtagcct ttcgtgttta
   132481 tgacgaattt agtagcagcc aagtgattag gcaagatgat ggatatttgc ttgtcacggc
   132541 tgaaatgaca agagaaccgt ggcttatcgg tggattgctt tcatttggta ctcaggttga
   132601 ggtgatagag cctgtgtatt tgaaaacaca gttagcggaa aaagcaaaag aaatttatga
   132661 aatgaataaa gcatgacata aggtgtcagt atttatatga tatagtatat ttcataaata
   132721 aaagaaaata aatagacgag aaaggaaata cttatgaaga tattgattat taatggttca
   132781 ccatacaagg agaacagcac cacattaaaa ataacaagag cttttatgga ggggctgaac
   132841 gagactgcgg agattgtaca tacgattgat ttggacataa atccgtgtcg tgcctgttat
   132901 gcctgctggg tgaaaacaaa tggcaaatgt gtacaaaatg atgaggcaat cgctgtcctt
   132961 aataaaatcc gtgaagctga tttagtaata tggtcaattc cattatattg ctactctgct
   133021 ccctcgcact gtaaagctct catggacaga accgtttgct ttaactcagc agaaatgtat
   133081 ttgggggatg atgaatgtac acaccactat ggatatgaag atggttctaa aaaaacagtg
   133141 ttgatttcct ctggtggttt gcccgatgta aaaggaaact ttgatggact ggtctttcaa
   133201 ctaaagcgta tgtttggcga aaataccgct acaatcttat gtgcagaagc aggattgttt
   133261 ttatcacctg aaacagaacc cttgacacta ccttaccttg aagctgcaaa aaaggcagga
   133321 acagaatata aagcaacagg tctgatttct aaagatacac agatgatatt agatgttcca
   133381 atgataccaa cagatatgta tattgcaaat gtaaatgcta ccttctctgc aatgaaagaa
   133441 aagaactaaa tttacgatac tgttgataag agcaaaatga tagatacaaa accatctgcc
   133501 ctaacaagta aaataaaaaa acgatgttgt gacagcagaa tagccatgtg cctaaagaaa
   133561 ataaagtagc ctaacggcgg tcaatggagt caatttagta caaaactaaa ttgatttctt
   133621 ttttataatc atatactaaa aaaatcgtaa aaaggtcttc aataattcat atatttttac
   133681 taatgaaaga tcaatatgac acaccaaagc gttatttgct tctattcaaa agagtgtcaa
   133741 attcttcttc tgataatttt tgaatgtatc tataactgtc cctccgtcct gctagtggta
   133801 aagttctttt taatggacat gaatggaaca gaaaagattt agaacagata ggagctttga
   133861 ttgaaactcc tccactttat gaaaatcttt ccgcagtaga aaatttagaa gtccgtgcaa
   133921 aattactgaa tattcccaaa atccgaatag atgaagtctt aaaaatagtc gatttgcaaa
   133981 atacaggaag aagttatcag agaaacaacg tgatgtaatc ttattacgct attttcaagg
   134041 catgagagac caagatattg cagaattata tcatgtatca cgttctgcta tttatcgcag
   134101 aagaagtaac ggattgaaga aactaaaagc attattgaaa gaaaggaatt gaaccaatga
   134161 gaaaagaata tggctatccc acattagaag taatatgtaa agcgtctgct ggaagtgaaa
   134221 ccgcaataaa ggtaattttg aaattctatg acgcttatat ctgtaaatta tgcttgcgta
   134281 ctttttacca ctctgaaagt ggtaaaatca ctatgcaggt tgatgaagaa ttaaaaggtc
   134341 aaatttatac agaaatgatg aaagcaatct tgaaatttga aatcagagtg aagtaatcat
   134401 attacacgaa tgaaaaacgg gagatacaca gatgtttgtg ctatctccca tgttgatttc
   134461 agtgtcatat caaggctcat tcaatcgtgg taaattcgtg gtaaaatgag tgttttccta
   134521 tacttcaaag tgcttgaaag tatagtgttt atgcgaataa tcaaaaaaaa gctataaaag
   134581 ttgtatataa atttaatata tttatcactc tcagataact tatcatcttc tggatactct
   134641 ttagcacaga gaatatctat tgttactttt ccttctttat cgtcttcaga catagaatag
   134701 aataaacttc gaatattttt ttcaggtggt ttttcagcac catttataga tactacaaag
   134761 ctaccatctg attttgagtt agtaatacta taaccactgt ctattatagc tttcgaaaat
   134821 ctttgagata aatctttttt tacttcttct ctacctttcg catcattaat cttttgtgag
   134881 taattattaa atagctcgat agattcatct tttttatctt caacttgttc tttcaatgaa
   134941 tctttactaa tttgttccga gctacttaag ttcttatcag atacaggaga catacatcct
   135001 accatcaatg ctaagctaag atttaaagcc acaattattg ccactctatt tatattcctt
   135061 tttactttca tacacaatcc tcccatcaca ctaaccgctc taaagtatta ttcattgcac
   135121 tagaatatat ttatattttc tttatattaa agatttatta ttcaatacat atcaccttcc
   135181 tatccaattc ttataactta ctattagtaa aattataagc tccttaatac agaaataagg
   135241 atgttatctt ttgttattaa aagataacat ccttattttt ttgtatcaat acatatgtcc
   135301 caactggtaa cttaatcgcc ccaactgtca gtatcttggt ccaatggtat atatatattt
   135361 agtataaatt tatcgatact attttcaaat aataattctc cattatattt ttgtaaagaa
   135421 gatttaatac tctgaatacc tattccatgt acgaacttat ccattttgtt tgttaacaat
   135481 atatttttat taaaagtaag ctgatttagt ttactatttt cacatttaag tacaaaaaat
   135541 gaccttgtta tagttccttt aattctaata tatttattaa tattttcatc cactatttta
   135601 tcacatgctt ctattgcatt atccaaaata ttagaaaata tgcttgacac atctataggt
   135661 tttacaaaat ttacttttga aaaatttata gagcaagtaa atttaattcc tttttttaaa
   135721 catacttcac tcttttcgtt gattataatg tctaatatca tatttcctgt attatagata
   135781 tatttaaatg tttttatttc atcttttaaa ttgttaacat attcattaat ttctttgcta
   135841 ttgtttctaa ggttgtctat acaataaatg tgattattta tatcgtgata tagtttctta
   135901 actcgcatat gagattcttg aatacttaaa taatgcgcat attgcatatc taacttattt
   135961 tttattaatt cagcttgaga ttttaatcta ttctctttta ttatttcttt aaacaatagt
   136021 ataagaaata tactactagc tcctaccaat tttggattaa caaaattatc aaaagtatcc
   136081 ttctgaatgt aatgacccaa accgttctaa tttttttaat acataattta caagcatatt
   136141 cattgtatta actaataagg caaataataa atatacataa tttctcttat cttggctaat
   136201 taattttata gacttcctaa aaaagctaaa tataagatat ataagaataa ttattaaatt
   136261 actatatatc tgaattttta tagattctaa gtgaggtact aataaggatt ctttagatga
   136321 aataacatta cctgtaattg caaaaaatag tattctatat ataacagcat ccaagcattt
   136381 ataatataca ctaaatagat aaaagaaaat ggaatactta atataaccca tcttataaaa
   136441 ataattatag tatcctcccc aagcaataaa tgctaatata taaaataaat agtttatatt
   136501 actaaagtaa tttccttcat taaataatct acttatctga attataatat aaataagaaa
   136561 caagacaata tagaatacta ttttttcatt ttttttacta tcctttttat aaattaaaat
   136621 tccgttcatt atagaaaact gtataaatat agataaaact actaatagct cagtcataaa
   136681 gtttagcata ttgtatcacc aagaaatttt aagaatttct ccttaacttc tttatatcta
   136741 tatctactaa taggtacctc ttctccactt tccagtattg cagcattagg ctttatattt
   136801 tcaacatatc ttaaatttac tataaaactt ttatggcatc ttataaattt atatggattt
   136861 aattcttttt ctattttacc taaactatat tttatatcaa aattcttgtt tattgtgtgt
   136921 attagcatat cttttttttg aacttctata tattttattt catttaaata aatcttatat
   136981 gtattagact tattttttat tgtaatatga ctttccttat ttatttcaat atctttgata
   137041 caagttagca catgtttttt tagttcttcc aactctattg gctttagtaa atacctataa
   137101 gctcttacct cataaccttc ttgcacataa tctattaatg aagttacaaa tattatttcc
   137161 atttcattgt ctacttctct aatctttctt gcagtatcca ttccatttaa tttttccatt
   137221 tttatatcaa gaagtaatat atctatatct tttaaattac tttccagtaa ctcttctcca
   137281 gatatatact tttgtatctc atattctata cttatatctt ttaatatatt ctcaaggtaa
   137341 tcttctatta aaagttgtgt ttctttttca tcttcacaaa ctgctatctt aatcataaaa
   137401 tgcctcctta cataatttct agttaataca attaaaatat ttataatata tttaaagata
   137461 attttgtata tctgatactt taggataaca tttttaaatt atttttatca atactcaatc
   137521 ccacacaact attatttgat atttcaattt aaagacagaa attactataa ttaaaaacag
   137581 tacttactga caaaagaaga tgtcttaaaa tattaaaaaa ataattttag gacaccttat
   137641 tttatttatt taaacttttt aagccttaaa taatacatta atctcctata taattgtact
   137701 acatataaaa tcaacaatat aatctgtagt acaatagcag ttacagatgc tccataacca
   137761 ctatataaat ttcttatttc aatattcaat aaatatataa atattactac taacataaag
   137821 aatacaaaca tattcataaa taaaactgac tttactttat ttgttttatc agaatcacta
   137881 tataatttag gaggtatgtc tttgtattct ttcgaccata tataccatgc agatgtaccc
   137941 ataaaactac caatactcct aaatacaaga ttccagccat ttgatttatg ttcatcaaaa
   138001 taattattct ctacatcata gtagtaatca acagtgtatt ttatttttct tggacttccc
   138061 ttatgaaaat aaaatattcc tccaaattta tttatcttat ataaattata tcctttagct
   138121 tcaatatctt ctaaccattt ctctatctta tcaggtgaac tataccagtc aaatttgaat
   138181 tttattttct tttccatagc actcattctc caaaatgata tttttaaata gcttaaaaat
   138241 ctatttaaat aattatatca ttttgatact aattttaggt tacaatcata tatttaaaaa
   138301 gctatttaaa tagtaataaa ctaatagcca taacacccat tcctgcaatc aatccataaa
   138361 tagataaatg atgttccccg tactctctag ctgatggcaa taattcatct agtgatatga
   138421 ataccataat tcctcctaca attgcaaata caattccaag agttatatca tttaaaaaat
   138481 ttctaagaag tacatatcca ataatcgctc ctaaaggctc agacatacca gataaaaagg
   138541 aataataaaa agctttcttt ttatctcctg tggcataata aactggtaca gatacagata
   138601 taccttctgg tatattgtgt attgcaattg caattgctat cggaatagct attgtaacat
   138661 catcaagagc tgatataaat gtagctaatc cttcaggaaa attgtgaatt gctatagcca
   138721 ttgctgtaaa tatacctgtt ctcaaaagag acttattttt tttgatattc ttttcttcta
   138781 tattctccat tttctttatt tcatgtggat tttcttcttg tggaattagc ttatcaataa
   138841 cagcaatgat ggccatacct ataaaaaaag ctattacagt tgaccaactt cctaatttct
   138901 ctcccataga ttttgtcaaa gcatcttgtg ctttaggaaa aatttctatc atagaaacat
   138961 aaatcataac accagcagaa aatcctaagc ttatagaaag aaacttagta tttgtttttt
   139021 tagcaaaaaa tgctatacaa cttcctatac cagtagataa accagccaat aatgttatca
   139081 aaaatgcaaa tattacatta ttcaaataaa tcaccttctt tttaattgat attgattatc
   139141 attttcttta tgctatcata tatattttat atagtcaata tttataaaaa atatacacaa
   139201 taaaaaagca gagatataaa cttagtctct gctttttctt tatagtatat taaaattatt
   139261 tatttaagaa atccactgca tattgcacat ataaagcagt tccaatttct agagcatctt
   139321 catctatatt aaagcatcca tgatgatgag gataacaagc accttttgac tcatttctag
   139381 ctcctacaaa tgctagtgca ccaggtgcta tattcataaa ctcagctaaa tcttctgctc
   139441 ctgttacttt ttcaaatagt gttatacagt cttctccaaa tagcttaatt gctgcatctg
   139501 tagctatctt tgaacattct ttgtcattta taactgctgg tgttaagtac ccatactcta
   139561 attcagcatc tgctctatat gcttctgctg tagattttgc tatacgttct aaaattccag
   139621 gaatttgctt tctaagctct ggattaaata gccttattgt accttctaag atagcttcac
   139681 tcgcaattac attaaatcta gttccagaat ttaaaactcc aacactcaca actaatggtt
   139741 ccagaggact tacttctcta ctaaccatag attgtagatt cataactatt gctgaacttg
   139801 caagcactgc atcaacacct tgatgaggaa gtgaaccatg accacctcta ccttttacag
   139861 taattttaaa gaaatcagca gaagccattc ttggtccttc ttctaccgat atggtcccag
   139921 attctacatc agtccaaaga tgtattccaa acacactgtc tacaccttcc atagcaccat
   139981 cttgaatcat agctcttgca cctttaccaa cttcttctcc tggctgaaaa aataatttta
   140041 cagttccatt gatactatcc ttaatatcat ttaacacttt tgctgcccct agaagcattg
   140101 atgtgtgacc atcatgacca caagcatgca taagtccttc atttttagat ttgtattcta
   140161 catcagtgca ttcaacaact tgtagagcat ccatatcacc cctaagtgct acagtctttc
   140221 ctggattagc tccttttata gttgcaatta cacctgtacc tccagctgat acatatggta
   140281 tccctatttt atcaagttct tctttaactc tctttgatgt tctaacttct tccatacttt
   140341 tctcaggatt ttcatgaaat tcccttctaa gcttaattac atagtcttta taactcttcg
   140401 ttatttcttt aatatccatt ccatacctcc aagtagtaca cattcttctt atttaaaata
   140461 ctttttatca cttaaatact atattagatt tacaaagata cctgctatta ctacagaagc
   140521 tattgtaact gtagtaaatc ctccaacaag catctttgga agcatcttat ccattaaaaa
   140581 ttctttttct tctggtgttt cagccaaagc ctttactgcc tcttcagtta atatatagtt
   140641 tggtggaaaa ccataaagtg atgtaagcga aactgaaaaa gccatttctt tactttcacc
   140701 taaaagctta cctactataa tagagaatat tcccatacct attacaccaa atattatgat
   140761 tcctacaaga ggaactgcca tttcaacaag cattgctggt gtagcttttg ctaaccctgc
   140821 aaatataaaa gccatcaatg atgtcattaa ccatccaaat gaaccagatt tattaagtgg
   140881 ttttctatca actattccaa gttctgatgc tattacacca aatattaaac atataacata
   140941 tcttgataca acttcatttg taagatttgt aaattgtact gctaaccatg ctacaaatcc
   141001 taatctaagt attatcatat atgtcgtatc atatttttct ggtaagtctg gtattatctt
   141061 aaatctgctt ttttgttcag gtaaatcctt aactttttct tcatctgtat ttacagttac
   141121 ttttccactt ctaaagtctg ataaaagtct ttttccttct tttttaagca ttaatgctgt
   141181 aataggataa cccgcaaatc cttgtgcaac atacatcaaa attgcaagta ctgataaact
   141241 tgcaagacct tttgctgtag cagcatctgc catcattata gatgcaacta gccctccagt
   141301 aagaggaggt gtagctatta ctgctgtatc ccatccaaat actactgtcc ctaatgccaa
   141361 agcacctaca catattccta ctattcctgc caaggctatt actattgttt tccattgacc
   141421 tgctaattcc ttaatactca tcatagttcc catatgagtt attaacaaaa gcatacctaa
   141481 ttgagctaat ggtgttccta aagcggctaa gtccacaata ttttctggga aaaaagtcca
   141541 aaatcctact ataaatataa ttgctgatac aaaaaccgac ggaacaaaag ctttagtttt
   141601 tgctgaaact atatctccta tcgtcagtga tactaaaact agacaaaaag ctgttattgc
   141661 ctccatacaa aatcccccct cataataaat atatttttat aaaatgtatg tatagttatc
   141721 cattatttta ctacttttga aaaacatttc aagtcaaaat tcgatttttt tcataaaatt
   141781 cgataaattc cataaattaa agttagtttt ctaaattatt ctttttgtaa aaacgttatc
   141841 ccgaccattg gctatttaac tctattctta caaagagaat taaatgtaat ttgcaaaaaa
   141901 taaaacatag gatacatttt attcataaaa catcttataa atataaaatg aattgtcttt
   141961 atgaatctta atatatccta tgtttgtaag tttaatgtgt atgttagcta tggtgtaaaa
   142021 tttgtatact agttattgtg taacctacta tatactccat ttttgtttac tagctcttca
   142081 tgagtacctc tttcttcaat tcctttatcc gtcaatacta tgatttcatc agcatttttt
   142141 atagtagtca atctatgtgc aacaactaaa tttgttctat ctttacttaa ttcctctaaa
   142201 gactcttgaa tttctctttc tgttacattg tctaaagcag atgtagcctc atccaatatt
   142261 attattggag gattctttaa aaagattctt gaaattgaaa ttctttgttt ttgcccacct
   142321 gataatttta cgcctctttc tcctatataa gtatcatatc catctggcaa agtctctaca
   142381 aagtcatgta ttctagcttt tttagcagca gctatcattt cttcatctgt agcattaggg
   142441 ttcccacaaa gaatattatc tcttatagtt cctgtaaata aaaatacatc ttgttgaact
   142501 atacctatat tttttctcaa tgattttaaa ctaacatctt ttatactctt tccatcaatt
   142561 tttatatcac ccttatcaaa ttcataaaat cttggcaata gattacataa tgtagtcttt
   142621 cctcctccag aaggtccaac taatgctata gtcttaccag cttttataga taaacttaaa
   142681 ttatccaaaa cttgagtctt atcttcatat gtgaaagata tattttctat ctcaatgtca
   142741 ccttttacat tttcaagttc aataggattt ttagcttctt tttgatggtc ttgttccatt
   142801 atctctatga atcttttaaa acctgtcata ctattttgat attgctctgt aaagtttatt
   142861 aattttttca taggttgtat aaacattttt acatatagta tataagcagc aaaatcaccc
   142921 aaagtaatct ttcctatata agtaaaataa ccaccagcta ttacaactac ccactctaag
   142981 atatccatgt ataaattcat accagagtaa tattctgcca ttactttata agaatcttgt
   143041 cttgctcttc taaataattt attgcttctt acaaacttat ttaactcttc tttctcagta
   143101 caaaaagact tagttacctt catacctgct atactatttt ctaaagtagc atttacatca
   143161 cctatagtaa ctctactctt cataaaagca atattcatct tatctttttt agctattgca
   143221 aaccaaatta taaacggtaa tatagcaaat attataagcg taagaggaat atttatatct
   143281 ataagtataa agaatgaacc aaccaacatt actatagaaa tgaataaatc ttcaggccca
   143341 tgatgtgcaa gttctgttat atccattaaa tcatttacta ttctagacat agttactcca
   143401 gatttgttat tatcaaaata cgtatttgga agtctttgta agtgtgtaaa tacctcattt
   143461 ctcatatcag cttgcatatc tacaccaata acatgtcccc aatactgcat aaaatagtta
   143521 agccctgctt ttgctataaa tataagtata agtgctactg caaaaactac taacattctt
   143581 aagtttttat ttggaacaac gtcatccatt atatttctag ttatcatagg ataaactaaa
   143641 tcacataagg aaaatagaaa agctgctata aggtctagtg taaaaatttt cttatatggc
   143701 ttataatatt tgacaaattg ttttatcata agtattaaat ccctccttta ttagtacttc
   143761 tattagtact tctaaaaaat acccataaat tagtataaca taacaataac tttaaatctt
   143821 ttataaactt acaaagtaat aacaatcttt ttcataaaat tgaagattta tatcatatag
   143881 ttgtatactt gaaacaacat aaaaagagct atatctctat attttaaatt ttataaagat
   143941 acaactctat atttaatact aaattttttt tataaataca aaactacttc aatgcattta
   144001 atatcttttt atctaatgct gttgtattta tacctgttat atatcctgtt gcctttattg
   144061 taggtatatc ataagttgtt ggtagtatag tagtagatac gattaaatca gcaccttctt
   144121 gttttgttga acattcagca attttacatt gctcaacttc tgcttgtata ttattttctt
   144181 taaccaatct ttctactctg tcacaaacta ttgttgatgt tgcgattcct gctccacagg
   144241 ctactaatat ttttttca
//
LOCUS       DAFAZV010000003       137801 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFAZV010000003 DAFAZV010000000
VERSION     DAFAZV010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 137801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 137801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..137801
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.003"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            50..166
                     /gene="rrf"
                     /locus_tag="KOU88_000303"
     rRNA            50..166
                     /gene="rrf"
                     /locus_tag="KOU88_000303"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            286..477
                     /locus_tag="KOU88_000304"
     CDS             286..477
                     /locus_tag="KOU88_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBK3210223.1"
                     /translation="MKKVALILAIIGALNWGAIGILGTDLIGSIFGGTYEMVSRIIYF
                     IVGLAGLYLIPSLMSDDRE"
     gene            632..2041
                     /locus_tag="KOU88_000305"
     CDS             632..2041
                     /locus_tag="KOU88_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBK3210224.1"
                     /translation="MFIINELNKIVNEEVISFHMPGHKKGQVYKKLGYKDILKNLYKM
                     DTTEILGTDNLHFPEGIIKNSQKKASRVFKSDYTCYLVNGSSCGIQSAIMSVCSPKSK
                     IITNRDCHQSVINGCILGDIDIEYVPCEISEETNILKGISISNVIDIIDKNLDAKAVL
                     LTYPTYYGMTYDLEYICNYAHSKKMVVIVDEAHGAHLGLSERLPKTALEQGADIVVQS
                     THKTLPAFTQSSMIHIQGDRVDIDKILNMLRITESSSPSYLLLSSLELAVDIYENKGK
                     ELMEELLNNIITFKNKVDSNINIYDTNDKTKIFISSKNMGLTGYELENILRNKYNIQV
                     ELSNYYGVLLICTIGNTVEDFSSLETALNNIVKEDFKFEKLENKKYPVVIPKKILTPR
                     EAFYKTKKSVKIYDSIGKVCGECIVPYPPGISVISPGEVISKEIIDYLMFCHSKGMIV
                     SGLKDVDLNFIQIIDLEDI"
     gene            2172..2861
                     /locus_tag="KOU88_000306"
     CDS             2172..2861
                     /locus_tag="KOU88_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBK3210225.1"
                     /translation="MKGKLIIIESGSDASGKATQTEILYERLKKEGYMIKKVEYPNYE
                     SPSSALVKMYLKGDFGKNASDVDPYIASTFFTADRYASFKTDWEEFYNEGGIIIADRY
                     TTSNMVHQASKMDICDREEYLNWLADYEFNLFKIPQPDCVIFLDVPIEFSKKLMENRK
                     NKITGEEKKDIHESDIEYLEKSYNNALYIADKYDWKKINCVLDNKLRSIESIHNEIYK
                     IVLDSIKPMER"
     gene            2864..3799
                     /locus_tag="KOU88_000307"
     CDS             2864..3799
                     /locus_tag="KOU88_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBK3210226.1"
                     /translation="MYFENIIGQDFAKKYLTNSIKKNKLNNAYMFEGMDGIGKKKFAD
                     ELSKLLLDYENLENSPDYVLIKPDGNSIKIAQIRNLQSDIVIRPHKDYKIYIINNAEK
                     MTVEAQNALLKTLEEPPNYAIIILVTNNKESLLETIKSRCDIIKFSPIPIEDLKRYLI
                     NTGIEEERAQLLAIFSRGSIENALNLSQSSEFSMMREDIQQYIQIMLDKNIVEILNIP
                     NNMEKYRGKIIALLDMMINYFRDIILLKENVNKNMLINVDKLVFIQNMSGKISYSQLS
                     KIIDIIEDAKSKIKSNCNFNISIQVMSLNIYEVIK"
     gene            3796..4689
                     /locus_tag="KOU88_000308"
     CDS             3796..4689
                     /locus_tag="KOU88_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBK3210227.1"
                     /translation="MIKIVGIRFKSAGKIYYFDPVDFNIEQDMDVVVETARGLEYGKV
                     VVGPKDMDESELVSPLKPIIRIATEEDKKVYLENKEKAKETFELCQQKIKEHELTMFL
                     IDCEYTFDRNKLIFYFTAEGRIDFRELVKDLAAIFKTRIELRQIGVRDEAKSIGGLGP
                     CGRKLCCSSWLGDFQPVSIKMAKDQSLSLNPTKISGICGRLFCCLKYEHDVYSEAIEK
                     MPVVGALVQSDDGKGKVVEVNPLLEQIKVEFQDKTVKIYTREDIKILREPKKCDGCGG
                     KCKDNDGLDEATLRELKKLED"
     gene            4767..5513
                     /locus_tag="KOU88_000309"
     CDS             4767..5513
                     /locus_tag="KOU88_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBK3210228.1"
                     /translation="MQLKDSERIDDLQLKGLKIIQDTNGFCFGIDAVLLANFTKIKKD
                     AKVVDLGTGTGIIPILIAGKSEAKKIIGVEIQEDVYEMATRSIKLNGLEERVEIINED
                     IKYIDKVLDINGYHVVTSNPPYMHIDGIKNPNDKKAISRHEVRCNLEDVIRAASRLVM
                     PRGKFFMIHRPTRLVDIITLGRKYKLEPKVIQFVHPRPQKAPNLVLIQFVKDGRPELK
                     ILDPLYVYGEDGNYTKELKAIYNNKDIGEL"
     gene            5514..6347
                     /gene="rsmI"
                     /locus_tag="KOU88_000310"
     CDS             5514..6347
                     /gene="rsmI"
                     /locus_tag="KOU88_000310"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBK3210229.1"
                     /translation="MSGKLYICPTPIGNLEDITYRTLRILKEVDLIAAEDTRHSIKLL
                     NHFEISKPLTSYHEHNKDSKGDYLINKLIDGENIALISDAGMPGISDPGEEIIKQAIQ
                     NNIEIEVLPGATAFVTALVGSGMDTHRFVFEGFLDRDKKVRKAQLEELKEESRTIIFY
                     ESPHRLKDTLKDMLKILGNRNISINRELTKKYQEIIRENIETTIKIFEEKEVRGEFVL
                     IVEGFHGEKSKKENYDGLTDREYVLKLIESGMNKKDAIKIVCKDRKLKKDVVYKQVLD
                     L"
     gene            6370..7074
                     /locus_tag="KOU88_000311"
     CDS             6370..7074
                     /locus_tag="KOU88_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK3210230.1"
                     /translation="MEIGKIIIESLKREDTHKIFIELDNKHELEKIIPKISCMKSVGE
                     CKYHVVNCFEHSINALKELEIVLNDRDFFPIHLRKHVSNYLKTYIEEGINKLNVLKLG
                     TFLHDIGKPDSMTLDETGRVHFTNHEKIGAQIIDNMGIKLELSTETYRLISKYVRYHM
                     ILLSLYKKNDLSRKELINVFNLVDEDTIGVIMLGYADIVSTVKLLGKSGEVSVLKTYM
                     EYILTNYLYKSNYTHV"
     gene            complement(7262..7690)
                     /locus_tag="KOU88_000312"
     CDS             complement(7262..7690)
                     /locus_tag="KOU88_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007287587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HBK3210231.1"
                     /translation="MDVTDYRIIEILQDDGRISMKDLGKIVGLTSPAVSERVKRLEES
                     GVIEGYKAIVNPDSLGRVIKAFIHISLPSNGYTEFIESAAKDPRIVECHHITGDDCLL
                     LKVIVKDMYELENVIDTIKKIGSTKTSVILSTPIQAKSIL"
     gene            complement(7727..9157)
                     /locus_tag="KOU88_000313"
     CDS             complement(7727..9157)
                     /locus_tag="KOU88_000313"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBK3210232.1"
                     /translation="MRNLTLLTDLYQLTMLNGYFEKNIHEDIVVFDMFFRKNACDGGY
                     TIVCGIDQVVEYIDNLHFSDEDLEYLKNLNLFSDKFLKFLKEFKFTGDIYAVEEGTIM
                     FPNEPLITVKAPLYQAQLIETALLTIVNFQSLIATKASRVCFAAQGDPVFEFGLRRAQ
                     GPDAGIYGARAAVVGGCAGTANVLAGKMFDIPIIGTQAHSWVQKFDNELEAFQAYADV
                     YPDKCLLLVDTYDVLNSGVPNAIKVFKNISEKGYKPMGIRLDSGDLAYLSKEAKKQLD
                     NAGFSDISITASNDLDEYTITSLKAEGATINSWGVGTKLITSFDSPSLGGVYKLAASC
                     EKGVLEPKIKISENPEKINNPGYKKVIRIYNEDNKAEADLIMLHDEVIDESKPLEIFH
                     PTYTWKTKVFTNYKVKELLKPLYIKGRCKYNKKAVLEIKNHVQYELSTIWEQYKRLSK
                     PHIYKVDLSRNLWYLKTQMIDSKKVL"
     gene            9289..9873
                     /locus_tag="KOU88_000314"
     CDS             9289..9873
                     /locus_tag="KOU88_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein"
                     /protein_id="HBK3210233.1"
                     /translation="MIIIGKIWFYMVSIGIIGSLISKNMGELNKVILSETSKGIEFAI
                     SLAGIMALWMGIMNIAKESGLIEKIGQKLNPIMKRLFPSIPKGHKAMSYIVMNIALNM
                     LGAGNGATAFGLKAMSELQTLNNKKDTATNDMIMFMVINISSIQIIPFTIIKLRMDMG
                     AQNPSEIIFTTLFATIISTAVAIITCKFFQRRYR"
     gene            9889..10410
                     /locus_tag="KOU88_000315"
     CDS             9889..10410
                     /locus_tag="KOU88_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore maturation protein B"
                     /protein_id="HBK3210234.1"
                     /translation="MEIFSNLLIPIIILYIVIYGKYKKIDVYDSFVKGAIDGLKAAWD
                     ILPYIIGIFLAIGIFKTGKGLDMLEWLFTPIANMMSIPKELIGLISVKPLSGSGALGM
                     YSELANRVGIGSLVEKMGATIVGSSETIFYTMAIYYGSLKIKNTRHTLSCAMISHVAG
                     VIAAVFICYVIFV"
     misc_binding    10476..10722
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            10806..12743
                     /gene="metG"
                     /locus_tag="KOU88_000316"
     CDS             10806..12743
                     /gene="metG"
                     /locus_tag="KOU88_000316"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBK3210235.1"
                     /translation="MSKPSFYVTTPIYYPSGGLHIGHTYSTVAADTIARFKRFCGYDV
                     KFLTGTDEHGEKIQKKAIEQGMSEIEYLDGMIKDIKALWNTMDISYDDFIRTTEKRHT
                     DIIQKIFTKLYEQGDIYKGEYEGRYCTPCESFWTESQLLEGNKCPDCGRETYLVKEES
                     YFFRLSKYEDRLKELFKDDSFCFPAARKNEMVANFLDKGLEDLSVTRTTFDWGIKVPF
                     DEKHVIYVWVDALCNYITALGYMTDNDEEFKKYWPANVQIVGKEIVRFHTIIWPALLM
                     ALGLEVPKQVFGHGWILFADDKMSKSKGNVVYPEPIIERYGIDTLKYFLLREFAFGQD
                     GSYTHRNFVTRINYDLANDLGNLISRTVAMVEKYNNGIIPTAKVSTDFDADLKEQAVS
                     TRENFEAEMDKMQFHEALESVWKLVRRTNKYIDETMPWALAKDETKKGELDTVLYNLC
                     ESIRIIATLINPIMNETANKIYEHIGIKGQDDITTWESTKTFGLIGENVKVFKGEPLF
                     PRLDVEKEIEELTKMFSGKPPVEEKPLEHKEEITIDDLDKIELRVGKIISCEKHPKAN
                     KLLVSQVKIGPETRQIVSGIAEYYKPEDLVGKEVTVVCNLKPVKLRGVESQGMILAAG
                     DDGDPYVLPFTQGAKDGCEVR"
     gene            12773..13543
                     /locus_tag="KOU88_000317"
     CDS             12773..13543
                     /locus_tag="KOU88_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBK3210236.1"
                     /translation="MLFDSHAHLNDESFDEDRDELIGSLKDKGVDLVVNPGADIETSI
                     TAIELAKKYDFIYSAVGVHPHDVSKLDDTAIETLRKLATENEKVVAIGEIGLDYYYDY
                     SPREEQKEWFKKQIELANELKLPIIIHDRDAHGDTFEIIKNTKNPEIGCVLHCYSGNV
                     ELAREYVKMGCYISIPGTVTFKNNKKTREVVREIPLERLFIETDSPYMSPEPHRGKRN
                     NPSQVSFVADKIAQEKGISYEEVCRVTKENAKKFFNIK"
     gene            13881..14312
                     /gene="phnG"
                     /locus_tag="KOU88_000318"
     CDS             13881..14312
                     /gene="phnG"
                     /locus_tag="KOU88_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBK3210237.1"
                     /translation="MYTVDSTKILINMNLEKLEKIYSMIKDTSSISIIKEPNLATVMV
                     RANESVKNTTFNLGEILVTECSVKVDESLGYGIVSENNNKKAIYLAVIDAVLHSNNSK
                     FDELKNYINKSVYEENLRYEQEIIDEFSLINKTKVQFNAMD"
     gene            14327..14902
                     /gene="phnH"
                     /locus_tag="KOU88_000319"
     CDS             14327..14902
                     /gene="phnH"
                     /locus_tag="KOU88_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBK3210238.1"
                     /translation="MVNYTQEIYRKMLDSASFPGKLNNIDNINIENNTKLLNGAIGIA
                     ITLLDQEVTFYIENYTQKDIKNIRALTMSNQIDYRKSDYIFLDINSEVDILQIKIGSF
                     EYPDESATIVHQVNDLSTYSQTKYIKLDLSGPGIKSKNSIYINGIREEFIERLSTINK
                     DYPIGIDLILVDKKGEIAFIPRSSKLSWEVL"
     gene            14905..15990
                     /locus_tag="KOU88_000320"
     CDS             14905..15990
                     /locus_tag="KOU88_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-phosphorus lyase complex subunit PhnI"
                     /protein_id="HBK3210239.1"
                     /translation="MAYVAVKGGEEAILQAKNILEFYRVKGDSLPIDVKQIEEQMSYA
                     VDKVMSEGSLYNKELSALAIKQAQGDILEASFYVRALRSTMPRITYSEPINTEEMRIK
                     RRISATFKDIPGGQYLGATRDYENRILNVELLEEDEKKNRDFRDSFISELETVDEIPE
                     FTKISNIFRKENLLQEEVCENKLEEVIDDITRNSLRFPVSRSAKLQALTRGESGVVSG
                     FAYAIVRGFGDEHPYISELRTGNVFIKVKHPIYEDEEIIIGDMLVTECEIVSKASQNK
                     TENSKTNSEDKNKMSLGYGLCMGNNENKAISMAILDKSLEPNSEKLAQDEEFVLLHID
                     GIDSLGFISHFKLPHYVDFKADVERIK"
     gene            16010..16879
                     /locus_tag="KOU88_000321"
     CDS             16010..16879
                     /locus_tag="KOU88_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBK3210240.1"
                     /translation="MIYNYGFLDENTKKEIRRKILKAISIPGYQVPFGSRELPIAKGW
                     GTGGLQLTLSLIGKNDVVKVIDQGSDDSTNACNIRSFIASVSNVETTKDTLEATLIQT
                     RHRIPEEKLKSNQILIFQVPIPETLRIVEPSEVETRRMHSEEDYSRMWVYLYEDIVRF
                     NDISIAVEYPCKVNDRYLMNPSPIPRFDIKKLNMSDNLFLFGAGREKRIYAIPPYTKV
                     EPLEFEDYKFEEEKFEGKYCSLCNSTNTFLDEVYDSDTNEKYYSCSDTSYCEKVRLKN
                     NSIDVTIGGTWNE"
     gene            16872..17738
                     /locus_tag="KOU88_000322"
     CDS             16872..17738
                     /locus_tag="KOU88_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3210241.1"
                     /translation="MSKINDSKRLENIDKQVLIGRNINLIYGDGCEKCFESTGYESNN
                     ICKYCGSIVACNNVNLELYEGEVLGIVGESGSGKSTLLKILFFQEHANSGEVYISHYN
                     KDTNILELSDQKKRYIKNHFMGIVYQNPHLGLNLDFSSGGNIAEKLLMANLYNVEKIR
                     DRGKELLIKTNIPVERIDHKPKYFSGGMQQRVQIAKALSNNPPILLLDEVTTGLDVSV
                     QAEVLDLIREIQRELKISMIVVSHDFDVIKMLADRTIVMKNGSVIESGLTDQIMEDPQ
                     HPYTQQLINSLL"
     gene            17779..18492
                     /locus_tag="KOU88_000323"
     CDS             17779..18492
                     /locus_tag="KOU88_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3210242.1"
                     /translation="MKETILEVNNFSKDFELHALNKTITACSNISFEVSKGEFLGIIG
                     KSGAGKSTILKSIYKTYIPTTGEIIFNSEIYGNVDLAKIGDREMINLRKKEIGYVSQF
                     LKTLPRITAIELVVHSLIESGFEKDCSYDMAKDILNQFEIKENLWDAYPNNFSGGEKL
                     RLNLAQAMVKKPRLLLLDEPTASLDNQSKIYVKEKMLELKSQGTTMIGIFHDIEFMET
                     VIDKTFTMTKGTISESGVA"
     gene            18493..19662
                     /locus_tag="KOU88_000324"
     CDS             18493..19662
                     /locus_tag="KOU88_000324"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBK3210243.1"
                     /translation="MIKLIHNANIVLEDMILENGHLIIEGDTIKKVSNDKIDYAFDFN
                     EIDEIIDAKNLYVIPGIIDIHSDAIEKEIEPRPSTLLPFNMAFYELDKKLPANGITTV
                     YHSISLGDGVGVRSIDNSLKMIKNIDSYKNIDSKSINHKVHLRYEVLYYEGLEKVLEL
                     LDENKIDYLSIMDHSPGQGQYTNPTFYKEYATKVWGVTENYVDTWLDDLVNLHDNLDW
                     NKIANIIGIAKTKNINVASHDDDTLEKMDFIKNIGINVSEFPITLEVAKHSKKLGVLT
                     CLGAPNIVRGKSHNNNLKAMDAILEDCCDIVCSDYLPSAMIKSMCIVAERINNLNKAV
                     SLFTSNPAKAVGIYDERGSIKENKKADLVLVDIDSEYPKVVNTIVNGKTVYKREV"
     gene            19666..20502
                     /locus_tag="KOU88_000325"
     CDS             19666..20502
                     /locus_tag="KOU88_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBK3210244.1"
                     /translation="MLTELHCHTSISDNNFTTEEIIKKAAEKNINILAITNHDTLSGL
                     DEALVLGEHYGITIIPGIEISAYDYKNRKRVHILGYNIDLNSQEIKNLCNPMVCDRHK
                     ASVKMVNKIIDLGYKISLEDVKKYSSKTGIFKQHIMKALIDKGYTDNIYSNLYKELFH
                     RGNGKVYVSLKYVDYRDAIKAIKNSGGICVLAHPGQMDNFSAIEEMVKVGLDGIEVYH
                     PSHNKELEKESLSYAKKYNLVVTGGSDYHGFYSQHNYELGSKSLNKEDLFKFRLALGG
                     VL"
     gene            20503..21498
                     /locus_tag="KOU88_000326"
     CDS             20503..21498
                     /locus_tag="KOU88_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3210245.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHGGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSNIDKKVKEVLEVVELSGYEKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIRSLHRKLGITTIMVTHDQEEALCLADKMVVMNRGEIIQVGTP
                     KEVYKNPETPFVADFIGTINFIDDGINKIAIRPEDIKVESNRDSKDKDIKVGEILDIE
                     FRGFNYRITVEYRSKQMKLDVVSKVAEQMKLCIGSKINFKIPKEGIVQYKSEGCA"
     gene            21516..23204
                     /locus_tag="KOU88_000327"
     CDS             21516..23204
                     /locus_tag="KOU88_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBK3210246.1"
                     /translation="MITSKNKRRISDSTIQKYFLIFSVIVLIVFILFPLVSLLKNAFM
                     DTSGNFIGISNFSKYVENPSLIASFKNSIFVSTVSSLISLCLAFIYSYAITRTNIKFK
                     DFFKTMGMFPLFAPTMLYGISLIYLFGNKGIFTTMGLEVPLYGPLGIIISQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFCKITIPGIKYSLLSSFFVSFILAFTDF
                     GAAKVVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTLDKMASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIVCSFITLLIFILIFVSVIGSVIKLWPYNLSFTMEHY
                     TFKGILGSGIKTYLSSLKISTLTAIFGTIFVFFSAYMIEKVDKFPKLRQTAYLLSMIP
                     MALPGLVLGISYITFFNSASNPLNFLYGSTAILVIVNVVHFYSVCFITSNSSLKMLDK
                     EYELVAKSINIPFYKVFFNITVPMSITSILEIVVYYFVNSMVTVSALIFLYTPQTQTA
                     SISILKLDEIGYIGPSAAMAVLVLLTNIIVRLLYEFVTKKLKNNTQKWQQKDVA"
     gene            23216..24283
                     /locus_tag="KOU88_000328"
     CDS             23216..24283
                     /locus_tag="KOU88_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK3210247.1"
                     /translation="MKFKKLVSLGVLSTLLLSVITGCSTDSSGSDSKSDSKTKGDLTV
                     YTAIEEDSIEPYLATFKEKYPDIKLNIVRASTGDITARLLAEKDNPQADVVWGVAATS
                     LLVADDQGMLEPYAPKGSEEIESAFKDDKEVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPSSSGTGYLTVSALIQIMGEEKAWQYMDKLHENIGVYT
                     QSGSAPATSAASGEYPIGISFGYRGIKLKEEGYPVEVVFPKEGSGWDIEANALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNYAVTTISTGNPIPEGFPKKPLEQMIDNDLKSAAK
                     NREDILNKWISKYDGKTEKES"
     gene            24720..25715
                     /locus_tag="KOU88_000329"
     CDS             24720..25715
                     /locus_tag="KOU88_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3210248.1"
                     /translation="MSFLQVKNVGKSYGQVKVLKDISIDIEKGEFICLLGPSGCGKST
                     LLRIIAGLEDKHDGKIIINDKDMTNSPPESRNFGIVFQSYALFPNMNVYKNIAFGLEN
                     KNISKSDIDKKVRDILEVVELSGYDKKYPSQLSGGQQQRVALARAIALEPDFLLLDEP
                     LSALDAKVRLKLREQIKSLHRKLGITTIMVTHDQEEALCLADKMVVMNNGEVIQIGTP
                     KEVYKSPKTPFVADFIGTINFIDDDVNMIAIRPEDIKVEFNRDFKEIDVKVGEILDIE
                     FRGFNYRITVEYCSKQIKLDVVSKVVEQMKLCVGSKINFKIPKERTIQYKSEGCA"
     gene            25733..27421
                     /locus_tag="KOU88_000330"
     CDS             25733..27421
                     /locus_tag="KOU88_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBK3210249.1"
                     /translation="MITIKNKRRISDSKIQKCFLVFLVIALVVFILFPLISLLKNAFM
                     DTSGSFVGISNFSKYIENPTLIASFKNSIFVSTISSLISLCLAFIYSYAITRTNIRFK
                     NFFKTMGIFPLFAPAMLYGISLIYLFGNKGIFTIIGIEVPLYGPLGIIICQILFTFPQ
                     AFLILSVALSMADYRLYEAADSLGASEFKKFFKITIPGIKYSLVSSFFVSFILAFTDF
                     GAAKIVGGNYNVLATDIYKQVVGQFNIPMGATVSMVMLIPVLIAFTVDKIASKKQGMT
                     ITAKSMPYKIKENKFRDRVFLIACSFITLLIFILIFVSVIGSVIKLWPYDLSFTMEHY
                     TFKGISGNGIKTYLSSLKISILTAIFGTIFVFFSAYMIEKVDKFPRLRQISYFLSMIP
                     MALPGLALGISYITFFNSASNPLNFLYGSTTIMVIANIVHFYSVCFITSNSSLKMLDR
                     EYELVAKSINIPFYKVFFYVTLPMSITSILEVAVYYFVNSMVTVSALIFLYIPQTQTA
                     SISILKLEEIGYIGPSAAMAVLVFLTNIIVKLLYELTTKKLKTKTQKWQQKEVA"
     gene            27433..28500
                     /locus_tag="KOU88_000331"
     CDS             27433..28500
                     /locus_tag="KOU88_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK3210250.1"
                     /translation="MKFRKLVSLGILSTLLLSVITGCNNASSGSNLKSNNKIKGELTV
                     YTAIEEDSIDTYLTTFKEKYPDIKLNVLRLSVGDITARLLAEKDNPKADVLWGVAATS
                     LIILDDKEMLEPYAPKGFDKVNPVFKDDKKVPSWVGIDAWMTGITVNTKELSDKNIPV
                     PSSYEDLIKPEYKGLISMPNPASSGTGYLTVSELIQIMGEEKAWQYMDKLHKNIGVYT
                     QSGSAPAILAASGEYPIGISFGNRGIKLKGEGYPVEVVFPKEGSGWEIESNALVKKDN
                     IKEASKVFLDWAISKDAMNEYSKNFAVTTIDTGNPVPEGFPKNPLEQMIDNDLKSAAR
                     NREAILNKWIEKYDGKTEKES"
     gene            28692..29222
                     /gene="rnmV"
                     /locus_tag="KOU88_000332"
     CDS             28692..29222
                     /gene="rnmV"
                     /locus_tag="KOU88_000332"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBK3210251.1"
                     /translation="MIKEIIVVEGRDDVTAVKRAIDAELITTGGFGFPKGVMERIKAA
                     NERRGVIIFTDPDFAGEKIRKKIASEVPGCKHAFLPREEAKKDGDIGIENATPQSIIA
                     ALNKVRTENTEKRDEFKQVDLIRNGLIGNEEASLRRDALGKILGIGYGNAKQFLNRLN
                     NYGVEREEFIDALKQI"
     gene            29393..30262
                     /gene="rsmA"
                     /locus_tag="KOU88_000333"
     CDS             29393..30262
                     /gene="rsmA"
                     /locus_tag="KOU88_000333"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBK3210252.1"
                     /translation="MDRLSSHNATKEVVQKYNFKFSKSLGQNFLIDSNIIDKILSGAR
                     ITRGDNIIEIGPGIGTLTREMGKIAEKVVAIEIDRNLIPILKDTLSDLDNTEVVNQDI
                     LKVDIQELVKDKLNGGPVKLVANLPYYITTPIVMKFLEEDIPVTDIVVMVQKEVADRM
                     NAIPGTKDYGALSIAVQYYCDTEIVAKAPRHMFIPQPNVDSTVIGLHVRDKRKYDVHN
                     EDIFFKTVKASFGQRRKTLLNSLGGLGFLNKDEIREILKEANIDEKRRGETLSIEEFS
                     VLSNIINTKVSSK"
     gene            30328..31590
                     /locus_tag="KOU88_000334"
     CDS             30328..31590
                     /locus_tag="KOU88_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210253.1"
                     /translation="MGSKRKFKRDYIILEAKDINFRYKERVLPKAFAKVEVNDEKAII
                     ALYVENLKYVKDGYKAVAIKDDHGLIDLGNIILNEQGRGEFVLDLEDYDDEIKGIALL
                     YERNIPLIGFKGNKLENYEDILFQEVEEEEYEEYEELEEEDEEIEDNEESDRDEDSEE
                     EYIIEEYDEDEYEDYWEDDEDSEEGELKARTEVEDSGDEEIEEFNNYKEIENYNRVKV
                     QEEYIDIEYDEEEEEEEVFEVNREEDRFVSSKPTKSKKVQKDQNNIEKIKRANGVSQG
                     ESGNKQTSTLLMPRQIKKGLKLFKEVKPFVTDYIDKTRWWKIEINPTTLCGYTMPYLG
                     YLNVLNYTMYSDAVLHSYKYRHYLFGVQYDEYNKRKHYIYAIPGNRNEQPDNGSTGFL
                     RYQACDNRTNSLGYWLCFIDSRQRNIVR"
     gene            31741..32856
                     /locus_tag="KOU88_000335"
     CDS             31741..32856
                     /locus_tag="KOU88_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBK3210254.1"
                     /translation="MINEQRILNEFLELVQIDSLSLKEGNVAKVLVKKLEEIGCSVVI
                     DNAGEKANGETGNIIATLKGNKEGKKILFSSHMDTVTPGIGVKPIVDEANGIIKSDGT
                     TILGSDDKAGIAAILEGLRYINENNIEHTDIQVVFSICEECGLVGAKNLDYGKIDSEY
                     AFILDSGGSPGEIIVKAPAQDVINVKVLGKTAHAGLEPEAGISAIMVAARAIENMNLL
                     RIDEETTANIGIINGGTATNIVTGEVNIVAEARSLKENKLDVQTKHMVETFEKAAKDF
                     GAQIEIDVNRAYTPIDVSEDSEIIKLAKKAFSNLGIEGHTESTGGGSDTNILSKNGIE
                     AITLGIGMKNAHTLSEHIAIKDLYDSAKMVVEIIKEA"
     gene            33042..33938
                     /locus_tag="KOU88_000336"
     CDS             33042..33938
                     /locus_tag="KOU88_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBK3210255.1"
                     /translation="METRYEEANKITIQSILWNIVLTIIKVIAGVIGNSSAMIADGLH
                     SASDIISSIGVLIGNYVSSRPGDREHNYGHEKAETLVSFVLSILLIFVSITIGIEAIK
                     SLFNLDALSVPSILPLVVSVISILIKEYQYRITIKVAKKINSPALKADAWHHRSDALS
                     SVAAFIGIGGSILGFKPLDPIASVVVAIFVAKVGISILISSVNELMDVSVDEEEIKEL
                     KFIVADTEGVKNLGDIKTRKHGAMAYVDLTICVDENLTVKQGHDIATKLEKHIIKHME
                     FVKGITVHVEPCTNCQGNKCNN"
     gene            34008..34805
                     /locus_tag="KOU88_000337"
     CDS             34008..34805
                     /locus_tag="KOU88_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210256.1"
                     /translation="MSKKRKLKKKAAILIGVVVFFIIYFISFRIGINMEKDKSEVPKK
                     VEKEEEDNRSLRTQIKEKKKVYISDKNIENIKIEEDMWDEIKLFFSDFKKVRNTTSSY
                     EAVYEGYSDDGVKFSTDLNFFRVYTVNKEEYYKVPVSSKDAFKKLLDESIYTSFDLLS
                     HYKDWKEVTITHGKEIKKVHRWKFDDLAHKMISKRVVGKVQPEKSKERSDYNFTINIK
                     GDNFDVKVDTMGKDYVKVTSKKNVSYYEVHTSLFDYLKNEIFEIGKK"
     gene            complement(34860..36212)
                     /locus_tag="KOU88_000338"
     CDS             complement(34860..36212)
                     /locus_tag="KOU88_000338"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBK3210257.1"
                     /translation="MNIHFIGIGGISMSALAEICINKGYQVSGSDSNESYLLDKLRDQ
                     GATIYIGQKKDNISDDVNMVVYTAAVHPDNEELVAAKEKNKLVMNRATFLGQIMREYK
                     NSIAVSGTHGKTSTTSMLSTIFEYADLDPTILVGGNLSMIGGNVKIGNSNHFITEACE
                     YVDSFLNFNPKISIVLNVEEDHLDYFSGIDEIKASFNKFGKLLPPEGYFIINGDDENI
                     DDILYDVKATIIKYGRDSDNDAVIKDIHFDNSGHGIFRIEYEGRDLGEFELSVYGLHN
                     IYNASSAIMAALVSGIDLETIRKNIKIYKGVGRRFETKGYYKNALVVDDYAHHPTELK
                     ATLAAAKKLKKSTLWCIFQPHTYTRTKSLLGEFSEAFYAADKVIITDIYAAREKDPGD
                     IHSKDLVEKLYQNNVDAIYIKEFEDIVKYLRENVKDNDLVITAGAGPIYKVADLLVEK
                     "
     gene            36431..37309
                     /gene="purR"
                     /locus_tag="KOU88_000339"
     CDS             36431..37309
                     /gene="purR"
                     /locus_tag="KOU88_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBK3210258.1"
                     /translation="MKFKRTERIGAIVKILSDNPNKIYTLSYFTNQFNAAKSTISEDL
                     LVVKNVFEKLHLGKVITISGAAGGVKYIPKTSIAENAEFLMELCERICDKSRILSGGF
                     LYLIDLIYDPTIAAKIGKIFASNIEYVDADYVVTMETKGIPMALMTAKAMNLPLVIIR
                     KDIKVSEGPTLSMTYVSGNSSKVESMSLPRKALKPDSKVIIIDDFMRGGGTIKGMVDL
                     MNEFGAEVIGTGVFISTTNPSEKMVKDYISLIQLDVNGDKIVVEPNLKTFKDEYRNED
                     LDEEEDSEFEFEIDED"
     gene            37465..37743
                     /gene="spoVG"
                     /locus_tag="KOU88_000340"
     CDS             37465..37743
                     /gene="spoVG"
                     /locus_tag="KOU88_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HBK3210259.1"
                     /translation="MKITDVRVRKLTEEGKMKCIVSITFDNLFVVHDIKVIEGHNGLF
                     IAMPSRKVGEGNFRDIAHPINAEMRQVLEDAVLQAYHEALVQWEVAAE"
     gene            37956..39335
                     /gene="glmU"
                     /locus_tag="KOU88_000341"
     CDS             37956..39335
                     /gene="glmU"
                     /locus_tag="KOU88_000341"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBK3210260.1"
                     /translation="MNFKAIILAAGKGTRMKSKYPKVIHKVCGKEMVNHIIDVSKKSG
                     VKDTVVILGHEADVVKEKLAEEIIIAMQTEQLGTGHAVKMAKEYINDEDTIVVLCGDT
                     PLIKEETLKRLFEYHIENKYHATVLTTRVGNPTGYGRIIRDKKGDLLKIVEQKDANSE
                     EKMISEINSGIYCFNGKSLREALDLLNNNNSQGEYYLTDTAKIMRDKGLKVGAFAGST
                     IEELMGVNSRVELSKAEEIMRRRINESHMVNGVTIIDTNSTYIESDVMIGNDTIIYPG
                     VMLQGKTRIGSDCIIGMNSSITNSEIGDGTEIKNSTIIDSKVGENSTVGPYAYLRPKS
                     DLGNNVKIGDFVEVKNAIIEDGSKASHLSYIGDAHVGKNVNIGCGVVFVNYDGKNKFK
                     SIVKDNAFIGSNSNLVAPVVVEEKGYIATGSTITHDVPDGALAIARERQVIKEGWVEK
                     KNQKDDQSK"
     gene            39430..40380
                     /locus_tag="KOU88_000342"
     CDS             39430..40380
                     /locus_tag="KOU88_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="HBK3210261.1"
                     /translation="MNTSGSEIKIIAGNSSKELAQKIADYIGVSVLDCEVGTFSDGEI
                     CVNMNETVRGCDVFVVQSTNSPVNDNLMELLILIDALKRASAGRITAVIPYYGYARQD
                     RKAKARDPITAKLVANLITAAGADRVLTMDLHAAQIQGYFDIPLDHLLGGTILANYFN
                     EKKIEDLVVVSPDLGSVTRSRKFANTLNGEVPIAIIDKRRPKANVCEVMNLIGDVKGK
                     NVILLDDMIDTAGTIVNAANALKEFGAKDVYACCTHGVLSGPAIERIANSEISELIVL
                     DTIQLPEEKRIDKIKIKTVAPLFGDAIRMIFSNESVSKLF"
     regulatory      41220..41305
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            41467..41988
                     /locus_tag="KOU88_000343"
     CDS             41467..41988
                     /locus_tag="KOU88_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBK3210262.1"
                     /translation="MKLKKNKKGFTLVELLVVIAIIGILAVVAVPALFSNINKAKVAS
                     VESDYSSVKSAALSYYSDTNKIPVTTTDKAGLTILETYMESLPDKADIGGKYKLIKVG
                     NKLVLQIGTDTEGVTLTEAQSAKLLSDIGKDKIYTGVTGDNFGDELTDTTKIDNKALY
                     IVLIDNTVMDSTK"
     gene            42140..43816
                     /locus_tag="KOU88_000344"
     CDS             42140..43816
                     /locus_tag="KOU88_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HBK3210263.1"
                     /translation="MAKKVRIGDKLVEKGYITEEQLKWALSEQKNSGKRLGEFLVQEG
                     LIDSNLLISVLKELLDIESIFLEGTEIDTLATKMVPENICKRYTVFPFKIDGNKICLA
                     MSDPQDREAVQDVRRMSGKDVEIFISSTEDINKAIGHAYAHSEINKAMTEYNKNRTGG
                     VRETVILEEDVNAAPIVRLVNNILENAVRMEASDIHIEQSENYMRVRFRIDGMLREYM
                     RMNSAPYKAVISRIKIMSDINISEKRIPQDGRIYLKVDNKPIDFRVSTMPTNRDEKIA
                     MRVLDKSNFMVSKEVLGIDEHGSKIYDELINTPYGLILVVGPTGSGKTTTLYSMLNQL
                     NTENRNLLTIEDPIEYELPGVNQSQINEKAGLTFASGLRAFMRQDPDIIMVGEIRDTE
                     TAEIAIRASLTGHLVLSTLHANTAVGAISRLLDMDVESFLITSSVLGVISQRLTRKIC
                     EHCKVSYEADIGEKKALGIDVNESVTIYRGKGCERCNNTGYKGRLGIFEMLEITPEIK
                     ELIDSSANQREILKMARKQGMVSLKEDIVKKVLNGKTTVEEMIRIILMTD"
     gene            43828..45036
                     /locus_tag="KOU88_000345"
     CDS             43828..45036
                     /locus_tag="KOU88_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HBK3210264.1"
                     /translation="MKSFKYTVIKEDGKKQTDVIEANDFNEARNLLRKRNLRVIEIKE
                     SKNKNIRLSSRKRKKDLGADQISHFCRQFAIIVSSGINSISGLETLARRSTNITLREE
                     INRIVAEIKVGSTIADSMLSSKSKFPKLLGAMVATGEATGKLDEVLKSMASFYASEHR
                     VKQKLRNAATYPLIVLISSFIMIFIFTTFMVPKMINSITTVGATLPLITRIVMGFGMF
                     MKKFWIIVLLVIILFIYQFKKYLKTSVGRAHKDRVINKIPVLGKGINCMVATRFSRAL
                     YLFVSTGYPLVQGLDYIIDSVNNTMAEKILASAKDGITRGEGLAENLERYTYFDSVLV
                     QMIAIGEQTGELENISRQMAEFYEYESEIYLNRMASMIEPVLIIAVGIIVAILVVSIF
                     MPMLSIYDAM"
     gene            45051..46763
                     /locus_tag="KOU88_000346"
     CDS             45051..46763
                     /locus_tag="KOU88_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBK3210265.1"
                     /translation="MNKVYVSYYGDSISIVEGRYKHDKDKFYVKNFNVFSIEDIAQDF
                     SKEKYALLRYALENVKLKSRHVVFCLNTRDVILKPQKLPNMDKKDLDGFMKLEMDEMM
                     ALESDEYVFSYEVSSETPDNSDGDESSLNLIIGAIQKEEVNAIVEIMHEFDLVLDRID
                     TLSTAYLRMLKNLDYNDIMVTNISDNSTIINIYKKDTLFISDNIPIKITAKDMDMQLL
                     NVVEESKGLMNYYSSRNFGKVTDTILILGKRYSNKLIYETFSSAFSSYVSQGLTEIMD
                     ISDMITGDIDEDDINSIVELLGSMIEPKGKRDFENINFLPMDILRKQIKAKQMKNILK
                     IAPIVILILAIPYLCLIFSNNLANKELENVNGEIRNIESAYYQIGNIEKMIQSKSEEI
                     KVYDMLIGKKVKWENLLDDIDKNTPSKVELTSLSTTYQNLGTNNKADNSKSNKTTTDK
                     SSNNETKSSTKSDSNGDKTDNDLNEDKTTNVSEALTGNSETNSNNTDKDDKTPLYDKI
                     PNVINIEGNAKDSSYVGQFLYKLKGLYYFKDVKLHSIKSNAEDSNYTFSMTLYLKEGV
                     LTNE"
     gene            46756..47664
                     /gene="pilO"
                     /locus_tag="KOU88_000347"
     CDS             46756..47664
                     /gene="pilO"
                     /locus_tag="KOU88_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 4a pilus biogenesis protein PilO"
                     /protein_id="HBK3210266.1"
                     /translation="MNKDIFKKDIKDIFKMEVSLKGILIKVIILLAILSYGYFGLYPQ
                     YQKYIATKNSVKQATEKLNIYKEKTALMPKYEKQLEEVESELKEKSKNLLYDMQDGLF
                     LIGLDKKMKAYNIDLTSYDVGNVKEYEHFYGISTTISVRGDYRNVKKLMAYLEEQKNV
                     TQILDYTMTSYIEPEKEEEETTNNKDLIKNVNINKDTKIYWVEGENKWHLYKDCPLIK
                     EGEILKNDKLLDRSTNYLCNTCVLRAATEKEAKKEVVAPKAEGVVDATFKFIMYTKEN
                     TTMILDTDNPSSWRPGKYNPFKSSAK"
     gene            47691..48257
                     /locus_tag="KOU88_000348"
     CDS             47691..48257
                     /locus_tag="KOU88_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBK3210267.1"
                     /translation="MSLYKNNEKGLTLLEVIIAVFILTIVLSISYKVFNGITSAVKKQ
                     QIITDAQVNINLINKYLNRDLENCKELTKTGSGNNYEYNIEMPDNVVKYEVSIETKKN
                     TEVYSVTRIQNNTIDTENEVREEIIYNQPLVQNNKEMKETPFKIEKQTGKSIYTVSIY
                     YNESVQESHKNSNLNNKTYTFDVMSRIG"
     gene            48294..48821
                     /locus_tag="KOU88_000349"
     CDS             48294..48821
                     /locus_tag="KOU88_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBK3210268.1"
                     /translation="MSKKNSERGFSLIEVLVAMAIMGIVLFAFFNIINTNNKANTKND
                     TDITSLNYVQSEIENLREKIKSGEFDFDSLDKLEDGTVVYEKLIDKSKKVVYDKVLSE
                     GDVSLYDTPYEKITTIKDEDGNLIDKGNITNKIKTIVEDKSGQIYKIAVTGKSMNDYS
                     SKKEVKIVTEIFKDK"
     gene            48842..50380
                     /locus_tag="KOU88_000350"
     CDS             48842..50380
                     /locus_tag="KOU88_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210269.1"
                     /translation="MRKWNKFKSERGAALVLVLVVVALLSIVGLIFSNQIANRIKSTK
                     TTNEGIQAKYLAETCVENSIDKAYEKLYDELEKMDNEFKSENQEKSISRSKLRDISDE
                     DFNNQDEENIEAERLGYMNNINFYLNKASSDLEKASMELKKLYDLDMLDYRDIEYVDA
                     NIISHRDSILEICKNYTSGDISKINEYILKEDIDSTTLIEAKLVNNDILLKMFLEENK
                     IENEHLNSAFSHTYKALDNISLAMQNMIEYRHTFHIDEPKVEVSNGIPDSQQYYELIQ
                     NPIINSMEYIWNSKWDTLEKLLEILPNQTQGFNSLRVHLRNNVRKFEKLSDNISSGKK
                     NTAKNFLKYKELLYEISDQCNQLKSMSYEKIPVKYDNMALITTFDYIQNELLAEIKCR
                     LKELKPQEIDKTEGITIKIPFYKADYDMTKEGWPKLKENGSGAELSLMVTGDKDGIKE
                     VEVTDGKKNIIGLGVEENSNSKYKVDAIVNFNLNIDTNVVGNYDIKDKILINHDISSY
                     KKVN"
     gene            50480..51562
                     /locus_tag="KOU88_000351"
     CDS             50480..51562
                     /locus_tag="KOU88_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBK3210270.1"
                     /translation="MYIYDLLEQGIRLNASDIHITVGTNPVARVKGGFVKLSEQILTS
                     EVTMQMAKDIAGESMFKVIEEHGEADFSASLKTGERFRVNAYRQKGNYAIAIRTITAE
                     IPTFEKLGLPESIKSFTEKHKGLVLVTGPTGSGKSTTLASMINIINEKQQKHIITLED
                     PIEYVHHHKQSLVNQREVGTDTESFHSALRAILRQDPDVILIGEMRDPETVSIALTAA
                     ETGHLVFSTLHTVGAAKTIDRIVDMFQPSQQQQIKTQLSTVCEGVVSQQLLPTADGKG
                     RIAAIELMFATPAIKNLIREGKTYQIPNMIQTGVKVGMKTMDQDLMELYKNGKITKDM
                     ALSRCTDQEFMTRMIGGVNYNGYYNR"
     gene            51543..52325
                     /locus_tag="KOU88_000352"
     CDS             51543..52325
                     /locus_tag="KOU88_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBK3210271.1"
                     /translation="MDIIIVNLYVFMVGIVFGSFFNVCIFRIPEGISISRPPSHCMSC
                     NTRLKPIDLIPVLSYLMSGRKCRYCYEKISSRYAIVELITGLLFLTVFMLYGISTSTI
                     YYLVLVSLLIIITFIDIDHFIIPDKILVFGAIFSMIFNLLFKEIPVKDSILGVFICGG
                     SVWIIVLLIEFVIKKECMGGGDIKLFAMLGFYMGVKNGLLTALLSVYVGAVYGICVII
                     ISRIKGKEYNSVIPYGPFISIGALITILCGKQLLELYFSMVI"
     gene            52427..53077
                     /locus_tag="KOU88_000353"
     CDS             52427..53077
                     /locus_tag="KOU88_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBK3210272.1"
                     /translation="MEYIIIISLFFAHLINKSLCVFCDREKKNLYNTFFIYIITVVLS
                     VLIYLKFGISVECVQYMVLIPFLIIISIVDYYTIYVYDITIVSGIIVQGIIFLVFFNI
                     VQFDYINHIFGLLIGFIIPYIIAKLTKGLGYGDVGLYSLCCFALGNNYGFYVIVLSFI
                     LAFLFFIILYITKIFKDVDIRKQIPFTPFISLSTILIIFTEYNIFNFYYNLLYKFI"
     gene            53091..53651
                     /locus_tag="KOU88_000354"
     CDS             53091..53651
                     /locus_tag="KOU88_000354"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBK3210273.1"
                     /translation="MYVVVGLGNPGKKYEKTRHNVGFDVIDILAKEYNISVTKIKHKA
                     LIGEGRVGTEKVLLVKPQTYMNLSGETLIDIYKYYKVDLSNIVVVYDDIDLEVGKIRI
                     RKKGSGGTHNGMKSITKCLGSNDFPRVRVGVSKPEAGQDLADFVLSRFRKEESDNINE
                     ALEKAADAIDSIIRENIDMSMNKYNG"
     gene            53668..57054
                     /gene="mfd"
                     /locus_tag="KOU88_000355"
     CDS             53668..57054
                     /gene="mfd"
                     /locus_tag="KOU88_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBK3210274.1"
                     /translation="MNDVFLYPLQNSKEYKDIINCIKNTKGSLLVNGLLPVQKPHISY
                     SIFNDLSRQMIFITSSDLEAKKVYEDLSFYMEDKVEYLGFQDIYFYHLDAKDRNEEAK
                     KLKVLLKLANKEKIILVTSIEAVLRKYIPKQVLLDSVSHYKVGDSLDLEKLTEKLVSL
                     GYERVSKIEGFGQFSIRGGIIDVFSLEYTNPIRMELFDDEIDSIRTFDVYSQKSIDKL
                     QQFSITPSREFIYPEKTTDALVKLKKETTKNTDEGTFQNIDYISSKTYFEGVENYIDY
                     IYPEENKSIFTYLADDAIVFINDITRLKERCENYINEFRENYKLNLERGLAIKNQGKL
                     LYHYTDLEYLVKDKSVVLNSLLPKSINNFSIKSIINFESREVPTFNGKVDLLVEELNR
                     LKYNGYKIILATNTLERANKLGKDLLDKGLETTISKDRDIEIKSSQVIIVPAHINSGF
                     QYKSIKFVVITDNEMIGVYKRASKTSNKKVKKGKKIESFLDLSVGDYVVHENSGVGRY
                     TGIEQITVNAIKKDYMKIVYQGGDNLYVPIDQMDKVQKYIGAEVEKVKLNKLGTNEWT
                     KAKAKVKKEIEDMTKDLIELYAKREKIQGYKFSKDTPWQAEFESLFPYQETEDQLKAI
                     EETKKDMESSKVMDRLVCGDVGYGKTEVAIRSIFKACMDQKQVAVLVPTTILAQQHYN
                     TFKERFENYPLRVEVLSRFKTPKQQKQIIEDAKKGLVDILIGTHRIISKDINLPNLGL
                     VVIDEEQRFGVKHKEALKKIKSTVDVLTLSATPIPRTLHMSLSGIRDMSVIEEPPQER
                     HPVITYVTESKESVIQDEIERELSRGGQVFFVYNRVEHIEEMASMIQKLVPDARVAVA
                     HGRMTSKSLENIILGFLNKDYDVLVCTTIIETGMDISNANTMIIYDADKMGLAQLYQL
                     RGRVGRSSRQGYAYLLYEKDKTLSEIAEKRLKAIREFTEFGSGFKIAMRDLEIRGAGN
                     ILGSQQHGHMAVIGYDLYVKMLNDAIKKVKGEPIVEEIDVEIDLSVNAYIPDNYIKDE
                     LIKIEMYKKIASIENKEDMLDIQEELEDRFSDIPKPVQTLLTIAYIKSLCKILKIEKI
                     RQLKDEILLVPITKYRTKQKIGYNIVTELEELLEKMCKVK"
     gene            57085..58080
                     /locus_tag="KOU88_000356"
     CDS             57085..58080
                     /locus_tag="KOU88_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK3210275.1"
                     /translation="MKKVITLVIAMILVVSVTACSSSKGETVATVEGTKISSDEFKKT
                     IALYKDSMEQTYGKDIWDKEVEKGVKYKDKFKDLILDQLITTEVIYSQAKKDNLLPKK
                     EDVEKSFKELKDAMGKDEKYKEQLKKLGIDDEFLRDQQEKDLAMQNYQSNFAKKTKIS
                     DEEMKKYYDTHKDEFKKDEVEASHILLKTVDDNNKPLSDKEKAEAKKKAEEALKEVKS
                     GEDFAKVAKKYSQDTSASDGGKLGFFSRGQMVAEFEDAAFSMKKGEVSDLVETQYGYH
                     IIKVTDRINEQTSFDDAKETIKDQLLKNKYQEQIEKLTKEAKVEKDEKVINKITI"
     gene            58204..58743
                     /gene="spoVT"
                     /locus_tag="KOU88_000357"
     CDS             58204..58743
                     /gene="spoVT"
                     /locus_tag="KOU88_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein T"
                     /protein_id="HBK3210276.1"
                     /translation="MKATGIVRRIDDLGRVVIPKEIRKTLRIREGDPLEIFTAKDGEV
                     ILKKYSPIGELNEFSQEYAETLAEVLGYGVLITDLDSIIAVSKLPKKDYKEKSISDEL
                     EAIISERTVKYSKDKNILPLFKEDQKEYTSQVIMPIISASGDCIGSIVVVSKDKDTIA
                     ESEEKSLKIAANFLGKQVQ"
     gene            58863..60476
                     /locus_tag="KOU88_000358"
     CDS             58863..60476
                     /locus_tag="KOU88_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK3210277.1"
                     /translation="MNNNKNKDSFLKGALILGLAGVIVKIMGGFFRIPLGNMIGSEGM
                     GYYQAAYPVYTLFLTLATAGFPTAVAKLVSEKVAIGNFKGANKIFKVSHTVLFITGII
                     SFCILFFGADYIVTNVMKNPGALYSMKAIAPALLFVPAMSAYRGYFQGRQDMTKIAVS
                     QVAEQFFRVVLGLTLAYLLMKSLGQTFGAAGAISGATIGSIASMLYLVFAYMLGRKER
                     RAEIDASQRFKDERVSYIFKKLLTVAIPITIGASVMPLVNMIDNVIVIRRLMEAGFTY
                     KVANSMFGQLTGMAMATINLPAVITTAMSMSLVPAISKAYALGNKSKARKDTKSAVKV
                     TLLIVLPCAFGMASLAIPIMGLLFPHEPSSVGTILFTLTPCVLFLGLIQTLTGIIQGM
                     GKPIVPVIALCVGMLCKIVISYTLTGIPDINVLGSAFGTVTAYFVAAMINLLYVKKHM
                     NVNFSKKEFIIKPFITVMTMFIMVKLSYGALVGFLGNSISTIIAICVGGIVYVVVILG
                     IGGIKKEEILTMPKGDKLYKLLKKVKLIR"
     gene            60583..62031
                     /gene="mazG"
                     /locus_tag="KOU88_000359"
     CDS             60583..62031
                     /gene="mazG"
                     /locus_tag="KOU88_000359"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBK3210278.1"
                     /translation="MGKISIVGLGPGDYSLISQGVLESLINSPKVFFRTEKHPIIDKL
                     KETIQYTSLDYFYEKEENFDNVYLKISEFIIEESAKGDLVYAVPGHPRVAEKTVSIIE
                     RLANEKHIAVEILPSMSFVDAMFNYLAIDPSEGFKLVDAFEIENSYIDLDTSMIITQV
                     YDKFIASNVKLKLMEHYDYNQEVCIVNGAGVKDLESKKFIKLCELDRNENFFDYLTSL
                     YIPKSSKKMYNTVHDLEIIVNTLRSPSGCEWDKKQTHQSLKNSVIEEAYELCNAIDNN
                     DIDEMVEELGDVLLQVIFHCQIGNEEGYFDLKEVVNGICKKLIHRHPHIFSGAKLDMS
                     KFEKTWEELKKEEKGESTITDGLRRIPKHLPALMKASKVQHKAALVGFDWDNVEDVFK
                     KIEEEYQELLDEHRVGNIKYIKEELGDLLFSIVNLARFLDIDSGEALNCTTEKFINRF
                     DFIEKSAMNLNKKLEDMTLEEMDEFWNQAKKQ"
     gene            62120..62398
                     /locus_tag="KOU88_000360"
     CDS             62120..62398
                     /locus_tag="KOU88_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003153447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBK3210279.1"
                     /translation="MNKAELVSKMAEKSGLTKKEAEAALNAFMSSVQDALVNNEKVQL
                     VGFGTFETRERAARQGRNPRDPEQVIDIPASKAPVFKAGKGLKDIING"
     gene            62470..62712
                     /locus_tag="KOU88_000361"
     CDS             62470..62712
                     /locus_tag="KOU88_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBK3210280.1"
                     /translation="MRLDKFLKVSRIIKRRTVAKDACDKGIVTINGKVAKSSSEVNIG
                     DTLEIQFGEKKMKFKINEVKEHVLKNDAKEMYEILE"
     gene            62774..63028
                     /locus_tag="KOU88_000362"
     CDS             62774..63028
                     /locus_tag="KOU88_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YabP"
                     /protein_id="HBK3210281.1"
                     /translation="MEQNITLKDRSKLVISGVEHIYSFNDKRVELKTSVGEMVIEGEN
                     LDMSKLSIDENIISIDGTINSMVYAKPKKPQESFLKKVFR"
     gene            63029..63562
                     /locus_tag="KOU88_000363"
     CDS             63029..63562
                     /locus_tag="KOU88_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210282.1"
                     /translation="MIPFTQDVSIFYATIYGGILIGVLFDFYRGLRGNFKFINYFAII
                     FDVLFWFLATVIIFVTINLTEFFDLRYYHFVALFIGFILYYNTISKIVLSIINKIIRF
                     VRNSFKKVTHYIVSFLNNLYYVIIYSLHLLFDIIFYIPNIFIATRKSIKRKSNKKLKN
                     KKKSKPKKKKNKTKKRV"
     gene            63568..63852
                     /locus_tag="KOU88_000364"
     CDS             63568..63852
                     /locus_tag="KOU88_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBK3210283.1"
                     /translation="MNLRKKFSGQIIVISLFLGISIFSMMTGFVFEYTKAKEYKKEIA
                     SLNKQLKKTEIQINSLKKDEKSYEGDLEDIARKRLNMVKPNETVYVDINR"
     gene            63965..64885
                     /locus_tag="KOU88_000365"
     CDS             63965..64885
                     /locus_tag="KOU88_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ppx/GppA family phosphatase"
                     /protein_id="HBK3210284.1"
                     /translation="MKVGAIDIGTNSMRLLIADYRDGNFINRKKFVNTTRIGYGVDSK
                     GYIKEDAIKRNIKALKEFSDKCNDEKCEKIYCMGTSALRDSKNGDYFVKLAKEETGID
                     VDIVTGIEESNLGFKGVLEGIQGDDTIIVIDIGGGSTEFIVGDSEGIIFNKSENVGAL
                     RMTERFLKHDIIEDEEFEAMSSFIYGEIDKTLNHIKDRGLKTLIGIGGTITSLSAMNQ
                     ELEIYSMEKIHNSKIHKKEIEEILQKLIKMTLSDKKNLKGLQEKRADIITAGVKILNI
                     IMEKLEIEEITVSEYDNLEGLICQKSKKMY"
     gene            64975..67347
                     /gene="spoIIE"
                     /locus_tag="KOU88_000366"
     CDS             64975..67347
                     /gene="spoIIE"
                     /locus_tag="KOU88_000366"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein E"
                     /protein_id="HBK3210285.1"
                     /translation="MQRSVAVVKNKTVKPNVIKLISGYIDFTTAAFAVMGFLLSRSII
                     VDSVAPLGIAFFICASKIDKYKIPVFISTLLGILLSSNDFGNVAKYAVCLTIFMAMNK
                     KLKLSDSIAKVAFIGAIILLPISMGQAFFSNRYVYGLLIAGVEAIIMFISIYVFSYGI
                     GLMANVNNRMSVRTEEAISISLLLTFSIMGIGDISLFGISIRTILSTVLILLTSIVGG
                     ATMGASSGVIIGVASILNNMTSAVYMGIYSFSGLISGAFNKINKYFCILGYILSWTII
                     YLYTSGITSNMMQLRDILLGSLIVLVLPERLFNKIEKLIKSNVASNEIVYDYIMRSKN
                     LTNSRLNSIYKTYDDLADTFDKIREKDKVLDQRDIANVIDMIHNDECKSCSMRRMCWE
                     SRFNHTYTMIYNILEKIEEKGELSLNDIPKNFRKECMKPESIVKISNHYYKMFVLDYD
                     WSVKFSESRKLIANQIRSISKSIKSLSQDLEGDIMLDIEKEKNIYEQLERYDITVDKV
                     SYLTKSNSEFEISIEKKTCHDGCMCEDKIVNIISDLVGENMSVRKIGCHCLGGKCKAT
                     FVKSQKYKAVTEVSAMSRDGHILCGDNYTYMEINDGKYMMAISDGMGKGKKAYEESSA
                     TIDILEKMIDAKIKDEIVIDTINNMLLLKSSEEMFSTLDLGILDLKRGCLETIKMGAC
                     STYIKREDGEVDLISSSSLPVGILSDVKIDRKNVKVKEGDYVIMVSDGIVDAGRNNNL
                     GDNWLIYFLKNIETTNPKEISNLILDRALELQALQIEDDMTVLVTKICTK"
     gene            67698..69590
                     /gene="pepF"
                     /locus_tag="KOU88_000367"
     CDS             67698..69590
                     /gene="pepF"
                     /locus_tag="KOU88_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBK3210286.1"
                     /translation="MNRKLCKAIIPLFISIFCMLIISIKADQGYQKNNDRAITVMNNN
                     DTEDDAEKKQEIDYEKTCWNLQSLFKSDDQWKKELKSFDKDTKELKNYIGKVTKSPTH
                     LSFALNIKEKLDIRLNKLSAYVKLKQDTNKNSYKYLDMNDSMSKSYGNYMGICSDLEL
                     EILKLSNKDYKKIISNKNINRKYGAYLRDIRRNKVHYLDDKSEDILSKVSSISSLPSQ
                     VYELFRNMDRKTNLTPAQYASELESSDRENRKKAYQDELITYNDNINTIAGLITGQVK
                     KNIFYSQERGYESSLEMYLESDNVDEKVYNNLIRTVNSNMDSLHKYIDLRKKVLKLDK
                     VHSYDMFVPMVKAVDNNINYEKAQSIVYSALSPLGKEYNDVVYKAFNEKWIDVYSHEN
                     KVSGGYCLSVYENHPYILLNYNNSLGSVSTLSHELGHAVYEYLSSKNQNYFNSNPSIF
                     THEVASTTNEALLYEMLIKEAKGNDEKAYYITQYLDLIKDTLYTQTMYAEFEKTIHEL
                     VEKGKSVNALVLNDVWGQLLKKYYGQSYELDQLSKVGWARIPHFYNSFYVYKYATGCS
                     AGVSFAQDILKNGSDNYMSFLKKGSSDYPINLLKSSGINLTNTKPIENTIKKFDSLVA
                     ELEKLL"
     gene            69704..70669
                     /gene="galU"
                     /locus_tag="KOU88_000368"
     CDS             69704..70669
                     /gene="galU"
                     /locus_tag="KOU88_000368"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBK3210287.1"
                     /translation="MQVKVKKAVIPAAGLGTRFLPATKAQPKEMLPIVDKPTLQYIIE
                     EAVASGIEEILIITGRNKKSIEDHFDKSVELELDLEKKGKKELLEVVQNISNMINIHY
                     IRQKEPKGLGDAIYCARHFIGDEPFAVMLGDDIVDNDVPCLKQLTDAYEEYRTTILGV
                     QKVNQEDTNKYGIIEAKNIEGRVYKVKDMVEKPESGKAPSNIAILGRYIITPEIFDIL
                     KDLPPGKGGEVQLTDALKILSKKEAMYAYNFEGKRYDVGDKLGFLEATVDFALKKEDL
                     KEDFIKYLKHVCSEFDKNNNVLYNNTDEKIDLIEVNEARELEIQK"
     gene            71169..72773
                     /gene="rho"
                     /locus_tag="KOU88_000369"
     CDS             71169..72773
                     /gene="rho"
                     /locus_tag="KOU88_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBK3210288.1"
                     /translation="MRRIFLILDDKVLEGLGSKTLVELREIAKELKIKSITTYKKNEL
                     IEIINSKSKNEEKVNEETKEKNEDIKEDIKNRKENIERESIEKEVEYKSPTKSYNKKE
                     IDTQNISQNQEHRNQRNDYNKTTSVNDSNKSSNISNRMVRNNNKNYYMPKQVDESKIV
                     DEFNTSKEDEVVGVLEILPDGFGFLRGSNYLSTEGDVYVSPSQIRRFNMKTGDKIKGI
                     TRHPKSGEKFRALLYVQKINDENPDTAIQRNAFETLTPIFPEERLTLETNRNEIATRI
                     IDLISPIGKGQRGLIVAPPKAGKTVLLKSVANSIAKNHPNVELIVLLIDERPEEVTDM
                     KESIEGDVIYSTFDQVSSHHVKVAEMVLNRAQRLVEHGKDVVILLDSITRLARAYNLT
                     ISPTGRTLSGGIDPGALHGPKKFFGAARNIRQGGSLTILGTALVETGSRMDDVIFEEF
                     KGTGNMELHLDRKLAEKRIFPAIDIYKSGTRRDDLLLDDEEKTALWRLRREMSNNSVM
                     EITDKVIELIKRTKDNKEFVKSIKNL"
     gene            72926..73126
                     /gene="rpmE"
                     /locus_tag="KOU88_000370"
     CDS             72926..73126
                     /gene="rpmE"
                     /locus_tag="KOU88_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBK3210289.1"
                     /translation="MQKEIQPKYNPVEVRCACGNTFVAGSTKDEIKVEICSECHPFYT
                     GKQKNIEKGGRIDKFKKRFKMD"
     gene            73271..74164
                     /locus_tag="KOU88_000371"
     CDS             73271..74164
                     /locus_tag="KOU88_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1385 domain-containing protein"
                     /protein_id="HBK3210290.1"
                     /translation="MAKQAVGGQAVIEGVMMQSKDKRAVAVRKSDGEIALKEDRIKSW
                     VRDKNIDKIPFVRGSFVMIDTMIQGIKSLNFSSEFFMEEAEEDKFDLFIKKIFKDKAN
                     DIIIIFSLVIAMLLSAGLFIFIPTLVGGAFSKVMPNDFMLNLIEGIIRIAILFAYIVL
                     ISRSKDIERVFQYHGAEHKSIYCYENDLELTVENARKFKRLHPRCGTNFLFIVMAVSI
                     ILFAFFGWPNPILRIFMRIICVPIVAGLSYEVIRVLGKYDNGFTKIIAYPGMMLQYFT
                     TKEPDDEQLEVALEALKAVVD"
     gene            74182..75030
                     /gene="prmC"
                     /locus_tag="KOU88_000372"
     CDS             74182..75030
                     /gene="prmC"
                     /locus_tag="KOU88_000372"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBK3210291.1"
                     /translation="MTIKDIIIKYSDKLKDISDTPRLDTELLLQKTLGVDRLYIHLNL
                     NKELTEEQKTKFMGFAEERLNGRPIAYIVENREFMGLDFFVKEGVLIPRPDTETLVEE
                     IIEICREKKDVSILDIGTGSGAITISLAKYIENSKIMSFDISETALEIAKKNAIINEV
                     GEKIKYINSDLFTAISDSNIKFDIIVSNPPYIKKQDIETLHKQVKDYEPYNALEGGED
                     GLDFYRRITEQGKKYLNKCGILAYEVGHNQAEDVINIMKSNGYKKIYTKKDIQGIDRV
                     VIGYNI"
     gene            75074..76138
                     /gene="prfA"
                     /locus_tag="KOU88_000373"
     CDS             75074..76138
                     /gene="prfA"
                     /locus_tag="KOU88_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBK3210292.1"
                     /translation="MLKKLEVLEDTYKDLSEKIGDPDVINDQKVWQKYIKEHADLEPI
                     VMKYREYKSVLDSIKESKEILQEESDEELRELAKMELAEMEEKVAPLEEEIKILLLPK
                     DPNDDKNVIVEIRGGAGGDEAALFAGDLFRMYSRYAERRRWKIELLSASDTGVGGYKE
                     VSFMIKGKGAYSRLKYESGVHRVQRIPSTESGGRIHTSTSTVAVLPEVEDVEVEINPN
                     DLRIDVFRSSGNGGQSVNTTDSAVRVTHIPTGEVVSCQDGKSQLKNKEQALKILKARL
                     YDKALAEQHKDIAAERKSQVGTGDRSERIRTYNFPQGRISDHRINLTLYKLDAFLDGD
                     IDEMIDALITVDQTEKMTAI"
     gene            76267..76947
                     /locus_tag="KOU88_000374"
     CDS             76267..76947
                     /locus_tag="KOU88_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBK3210293.1"
                     /translation="MILKVTIIGLLAGVIGTGLGGVISAIFKREVDKYLSFFMGLSGG
                     IMLAVVVFDLMKESMDKMGIINTVIFTFVGALITMYIKTKLDVSGNMASGYLIFISIL
                     LHNLPEGLAIGSSFMSTESLGITLAIVIGLHNIPEGLAMALGLVCNKMKLSKVILFTV
                     IAGLPMGLGSFLGVYFGGVFTSLIGVFLATAGGTMMYVVLEEIFPHSKSVYCIIGFLL
                     GTMIVNYI"
     gene            76976..78016
                     /locus_tag="KOU88_000375"
     CDS             76976..78016
                     /locus_tag="KOU88_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBK3210294.1"
                     /translation="MKTIISNIDINNIDYEEIKIQAKLLREGKTVIFPTETVYGLGAN
                     ALDENAVKKIYEAKGRPSDNPLIVHIYEKEEVYDLAKDISDKAKLVIEKLWPGPITII
                     LNKKDIIPYKTSGGLDTVAIRMPSNVIARAIIKEAGIPIAAPSANISGRPSPTKAKHV
                     YEEMNGRVDGIVLGGDSNFGLESTVLDLTEETPMILRPGSITKEVLEELLGEVKLDPS
                     LSKKEDNQKAKAPGMKYKHYSPNADVYIISGKRENVATKINDMIKSNRDKGLKTGVMC
                     ISRNREFYDGEVIDLGNSLEEVASNLFDALIEMDKKGVDVIYSEEFPKTGVGQAIMNR
                     LLKSAGYKVIKA"
     gene            78033..78482
                     /locus_tag="KOU88_000376"
     CDS             78033..78482
                     /locus_tag="KOU88_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HBK3210295.1"
                     /translation="MNILIVCTGNTCRSPMAEAILRKAIKESGRSIEEYSISSAGIST
                     ANGMGASENSIEVLKEIGIDLSNHRSKVITKKLIDESDIILTMTKSHKEILVQAVPKC
                     KEKVYTFKGFANKNEEDISDPFGGNLDIYRSTMREIMYSVNEIVKKI"
     gene            78499..78951
                     /gene="rpiB"
                     /locus_tag="KOU88_000377"
     CDS             78499..78951
                     /gene="rpiB"
                     /locus_tag="KOU88_000377"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBK3210296.1"
                     /translation="MKIGLGCDHGGYNLKKEIISYLESKGIECVDYGTNNATDSVDYP
                     VYGEIVANSVINKEVDYGILCCGTGIGISLAANKVPGIRCAVVSDVFSAKMSKAHNDA
                     NMLSLGERVLGKGLALEIVEAWINTDFEGDRHARRVNMIKSIEEKHNK"
     gene            78987..79616
                     /gene="upp"
                     /locus_tag="KOU88_000378"
     CDS             78987..79616
                     /gene="upp"
                     /locus_tag="KOU88_000378"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBK3210297.1"
                     /translation="MSKVVETNHPLIQHKLTLMRDKNTGSKDFRELLTEIAMLMGYEI
                     TKDIPLKDVEIETPIQKTSSKVVAGKKLAIIPILRAGLGMVDGLVSLMPAAKVGHVGL
                     YRDPETLKPVEYYCKLPQDIGERDIIVVDPMLATGGSAVAAIDLLKSKGAKSIKLANL
                     VAAPEGIAEVQKYHDDVDIYVASVDERLNEHGYIIPGLGDAGDRLFGTK"
     gene            79911..80726
                     /locus_tag="KOU88_000379"
     CDS             79911..80726
                     /locus_tag="KOU88_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBK3210298.1"
                     /translation="MKNCIVVRGAGDLATAVIHKLHNSGFKVVALEIEEPLAIRRQIS
                     FCEAVYEKKVTVEGVECIFCNTEKEIEEVLSQHKVALIIDPKGEKLSKLNPIVLVDGI
                     LAKKNLGTTKDMAPLTIALGPGFCAGEDVDVVIETMRGHNLGRIITNGRAEKNTGVPG
                     AIKGFSKERVMHSQYDGIMENVCKIGDIVEKGDLLCYINNYEKKHEVRATISGVLRGL
                     LKDGAKVNKNLKILDIDPRKEEVKNAFTISDKARCIAGGVLEAILNNGIYPQN"
     gene            80952..81389
                     /locus_tag="KOU88_000380"
     CDS             80952..81389
                     /locus_tag="KOU88_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBK3210299.1"
                     /translation="MRPSWDEYFMEIAEVVKKRSTCIRRQVGAVIVRDKQILTTGYNG
                     SPRNLEHCENIGCKRQELNIPSGERHELCRALHAEQNAIIQAAHNGISVDGATLYVTT
                     RPCVLCAKMCINAGILKIVYEGDYPDDMSTELLKEAGIELIKF"
     gene            81574..81801
                     /locus_tag="KOU88_000381"
     CDS             81574..81801
                     /locus_tag="KOU88_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AtpZ/AtpI family protein"
                     /protein_id="HBK3210300.1"
                     /translation="MSKRNTHTEIAKLFSLISQIGLMIVISILGCTFLGKFLDSKLNT
                     TPVLTIIFLLLGVGGAFSGVYKTLIVYTRRK"
     gene            81806..82192
                     /locus_tag="KOU88_000382"
     CDS             81806..82192
                     /locus_tag="KOU88_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HBK3210301.1"
                     /translation="MDIKLLNQVRSVTKGIVIFDVVLIVLMLITSTLSKPVLLGLIFG
                     SIIAMLNFRLLAISLEKSVTFPAGKAQAYASAQYAVRLFIMAVVLIASATVPHLNIIG
                     TALGLLSTKFVILSKNFINKLKRKEA"
     gene            82195..82899
                     /gene="atpB"
                     /locus_tag="KOU88_000383"
     CDS             82195..82899
                     /gene="atpB"
                     /locus_tag="KOU88_000383"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBK3210302.1"
                     /translation="MNQAHYYLIGNFKISETILVSWGIMAFLAIASYFLTRNLKKVPT
                     SKVQIFLEFAVGGLAKMVTDVMGKNTVKRMPYMIPYIGSLFLFFACSNLSPLLGLRSP
                     TTDLDTTAAWAMITFFMIYFAGVKFKGLSYFKELAQPLAIMLPINIIGELARPISLSF
                     RPFGNILGGTIIMGLFYQLLGFISSLIPGLSIPIGEILIPVPLHLYFDLFAGLLQAYI
                     FIMLTMVFISSAGELD"
     gene            82968..83228
                     /gene="atpE"
                     /locus_tag="KOU88_000384"
     CDS             82968..83228
                     /gene="atpE"
                     /locus_tag="KOU88_000384"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBK3210303.1"
                     /translation="METAIVAAASAIGAGIAVATGIGAGIGQGIAAAKAAEAVGNQPE
                     AKGDITSTLLLGVAIAESSAIYGLVISIILLFVNPFFKYLGM"
     gene            83351..83848
                     /gene="atpF"
                     /locus_tag="KOU88_000385"
     CDS             83351..83848
                     /gene="atpF"
                     /locus_tag="KOU88_000385"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBK3210304.1"
                     /translation="MEKALVGITWEFVFQIVNTFIIFLLLRKLLFKPVLNIIESREND
                     IKSDLAEGEKAKNEGLALKKEYESKINFAKDEGQEIIKQATIRAEQKSDDIVNTAKKD
                     ALDIKEKANKDIEQERQKVINEIKNDISNIALLAASKVIEKDLDKSKHEELIENFIKE
                     VGEAK"
     gene            83845..84390
                     /locus_tag="KOU88_000386"
     CDS             83845..84390
                     /locus_tag="KOU88_000386"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBK3210305.1"
                     /translation="MINVIANRYAEALFQLGEEENSTDVLFKELEKVVDMMTKVSKDF
                     YKVLKSPLVSKSEKKNLVEIIFSKEVSSNIKNFLKVLVDKDRISYLEDIELAYKELLN
                     KKNNVIDGVAISAIPMSETDIKELEVKLSNKYNKNVTIENVVDKTILGGVLVRIGNEQ
                     IDGTVKTRLDKMKEKLSEVIS"
     gene            84407..85909
                     /locus_tag="KOU88_000387"
     CDS             84407..85909
                     /locus_tag="KOU88_000387"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003405060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBK3210306.1"
                     /translation="MNLKPEEISSIIKQQIKNYENKVELTDTGSVLTVGDGIASVYGL
                     EKAMSGELLEFPGEIYGMALNLEEEVVGAVILGDDSEIKEGDIVKRTGRIVEVPVGEA
                     LIGRVVNSLGQPIDGKGPIAYTKTRPVESEAPGIIDRRSVYEPLQTGIKSIDSMIPIG
                     RGQRELIIGDRQTGKTSIVIDTILNQKGKDVICIYVAIGQKRSTIAQLVSSLEKGGAL
                     DYTIVVSATASESAPLQYIAPYAGAAMGEEFMYNGKHVLIVYDDLSKQAVAYREMSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDELGGGSMTALPIIETQAGDVSAYIPTNV
                     ISITDGQIYLQPELFYSGVRPAVDPGISVSRVGGSAQIKAMKKVAGTLKLAYSQYREL
                     AAFSQFGSDLDEDTKKRLAQGERIVEILKQGEHQPIKVENQVMIIYAVINNHLEDIPI
                     DNIARFESELYAFVDNNYPEISRKILGGEDFTHDLTDAINEFKEKFVVEV"
     gene            85937..86815
                     /gene="atpG"
                     /locus_tag="KOU88_000388"
     CDS             85937..86815
                     /gene="atpG"
                     /locus_tag="KOU88_000388"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit gamma"
                     /protein_id="HBK3210307.1"
                     /translation="MAGAGIKAIKTRMGTVESTKQITKAMELVASSKLRKAKEKAEDS
                     REYFNTLYNTVKDIAQTTRGIRNEFLKEREVKNKCYVVVAGDRGLAGGYNSNVLKESV
                     SHMKGKKETVITVGKKAHEFFSKRNYNIAKDINSVEACGYEDATEISQTIIDLYKKGE
                     VDEVYIAYTKFKSALSQEVEILKLLPLVFEKDTDEQGMAVKEEKQNRSKVQYIPSAEA
                     VLSYIVPQFISGTVYGGILESFASEQGARRTAMESATDNANEMLSNLELSYNRARQSA
                     VTQEITEIVGGVEALK"
     gene            86828..88222
                     /gene="atpD"
                     /locus_tag="KOU88_000389"
     CDS             86828..88222
                     /gene="atpD"
                     /locus_tag="KOU88_000389"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBK3210308.1"
                     /translation="MANVGKVVQIVGAVLDVKFDSEQSLPNLLNALVIKLGDKEIVAE
                     VAQHIGDDTVRCIAMSATDGLVRGMEVVDTGGPISVPVGDETLGRIFNVLGKPVDGKP
                     APKSAPKLPIHRPAPAYDELETTAEILETGIKVVDLLAPYLKGGKIGLFGGAGVGKTV
                     LIQELINNIAKQHGGISVFSGVGERTREGNDLYGEMSESGVINKTALVFGQMNEPPGA
                     RMRVALTGLTMAEHFRDEQGQDVLLFVDNIFRFTQAGSEVSALLGRMPSAVGYQPTLA
                     TEMGALQERITSTKKGSITSVQAVYVPADDLTDPAPATTFSHLDAKTVLSRQISSLGI
                     YPAVDPLESTSRILDPSIVGKEHYEVARGVQSILQRYKELQDIIAILGMDELSDEDKL
                     IVARARKIQRFLSQSFTVAEQFTGNPGQYVPVKETVRGFKEILEGKHDDLPESAFLFV
                     GTIEDAVRKAKGSM"
     gene            88225..88485
                     /gene="atpC"
                     /locus_tag="KOU88_000390"
     CDS             88225..88485
                     /gene="atpC"
                     /locus_tag="KOU88_000390"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F1 subunit epsilon"
                     /protein_id="HBK3210309.1"
                     /translation="MASEFSLKVVTPSNTFYDGDVEMIVVRTTKGDKGVLKGHIPFVS
                     GIPVGTLKIKKEGSFKEAKIAEGFINVTQDKTVILTESAEWI"
     gene            88947..89327
                     /locus_tag="KOU88_000391"
     CDS             88947..89327
                     /locus_tag="KOU88_000391"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBK3210310.1"
                     /translation="MNIFDIGVDIIEIDRIRKAVDKNNRFLEKIFTDREIEYFNSKNF
                     KAESIAGNFAAKEAISKSIGTGIRVFNFKDIEVLRDEMGKPIVKTYNNLAKMCIDYNV
                     LEIKVSISHSKDYAIANAITIIKD"
     gene            89342..89803
                     /locus_tag="KOU88_000392"
     CDS             89342..89803
                     /locus_tag="KOU88_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK3210311.1"
                     /translation="MMDKTAKEIMTTDVIVAKQDDSIADVANMLIAEKIGGLPVVDSE
                     NRVVGIISETDILKKEKYIEAPLYINLLQGLIFLDDLKKVEKDIKQVAAYKVGELMSK
                     DIIKVHEDDKFDDVANVMIKKSINRVPVVDDDNKLKGIICRYDIIKALYNE"
     gene            89824..90414
                     /locus_tag="KOU88_000393"
     CDS             89824..90414
                     /locus_tag="KOU88_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210312.1"
                     /translation="MRKKWTIVCIMFLALVIIVIGCQKRQSTKEEVYKDFQKQISDMN
                     YYSCKAEVEVVGNKSPHNYVLIHTYKKTDNYKLEVISPKHLKGKSIEYQGDKILVKNP
                     KISDVVELPNTGKNNQYLFVGDFIKNYLQNEEMKVKLSKGHLVLETFIPGDNKYFNKQ
                     VLYVNADTKNPEKMEVLDKEGVPRFTVKYKDFEYRN"
     gene            90429..91586
                     /gene="alr"
                     /locus_tag="KOU88_000394"
     CDS             90429..91586
                     /gene="alr"
                     /locus_tag="KOU88_000394"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBK3210313.1"
                     /translation="MQKITVPTWAEINLDNLRFNLNNIKNLLEEDIKICGVIKADAYG
                     HGAVEVAKLLEKEKVDYLAVARTAEGIELRQNGITLPILNLGYTPDEAFEDSIKNKIT
                     MTVYSLETAQKINEIAKSLGEKACVHVKIDSGMTRIGFQPNEESVQEIIELNKLEYID
                     LEGMFTHFATADEVSKEYTYKQANNYKFMSDKLDEAGVKIAIKHVSNSAAIMDCPDLR
                     LNMVRAGIILYGHYPSDDVFKDRLELRPAMKLKSKIGHIKQVEPGVGISYGLKYTTTG
                     KETIATVPIGYADGFTRIQKNPKVLIKGEVFDVVGRICMDQIMVRIDKDIDIKVGDEV
                     ILFGEGEVTAERIAKDLGTINYEVLCMISRRVDRVYMENNELVQINSYLLK"
     gene            91619..91906
                     /locus_tag="KOU88_000395"
     CDS             91619..91906
                     /locus_tag="KOU88_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBK3210314.1"
                     /translation="MYDKSKEKIEVTLPDSLISEVDSIVQMENSNREDFAKAAFQFYI
                     TQKKKIHIKESMKTGYREMGQINLSLAELGMTVEEVSSDDKNEGKIAQGEY"
     gene            91875..92258
                     /locus_tag="KOU88_000396"
     CDS             91875..92258
                     /locus_tag="KOU88_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBK3210315.1"
                     /translation="MKGRLPKVSTNCEIKRGDLYYADLSPVVGSEQGGVRPVLIIQND
                     VGNKYSPTVIVSAITSQINKAKLPTHVEISSNEYGLNKDSVILLEQIRTIDKKRLREK
                     IGCLDENMMIKVDDGLQISLGLFTF"
     gene            92429..93256
                     /locus_tag="KOU88_000397"
     CDS             92429..93256
                     /locus_tag="KOU88_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBK3210316.1"
                     /translation="MRDHKGLNEIARIIRRDIVSMIHRAKSGHPGGSLSVVEILTALY
                     FDEMNVDSSNPKMEDRDRFVLSKGHAAPALYATLAEKGYFDKEELNGLRKIGRMLQGH
                     PDMKGTPGVEISTGSLGQGFSVACGMAMASKLDNAPWNVYTLLGDGEVQEGIVWEAAM
                     SAAHYKLDNLIAFLDNNGLQIDGDIESVMSLGSIVDKFKAFGWNVIEIDGHDFDQIFA
                     ALDIAKSTVKKPTMIVAKTIKGKGISFMENQAGWHGTAPSDEELEKALLELGGADNE"
     gene            93249..94190
                     /locus_tag="KOU88_000398"
     CDS             93249..94190
                     /locus_tag="KOU88_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBK3210317.1"
                     /translation="MSKMATREAYGKALVKLGQINDNVVVLDADLSKSTKTHDFYKSF
                     PDRFFNMGIAEQNLIGAACGLSTAGKIPFASTFAMFATGRAFEIIRNSVCYPKLNVKI
                     CATHAGLTVGEDGASHESVEDIAIMRAIPNMTVLVPADGVETEKIIFEIAKYNGPVYV
                     RLGRSSVPVLFDEDYKFEIGKGTVLREGKDVSIIACGIMVNEALLAQEKLQEEGISAR
                     VINMSSIKPIDKDLILESAKETNAIVTVEEHSIIGGLGSAVSEVVGESCPTIVKKVGI
                     KDTFGESGTPNELLKKYELTCDDIIKTVKEAIIAKRM"
     gene            94613..95707
                     /locus_tag="KOU88_000399"
     CDS             94613..95707
                     /locus_tag="KOU88_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210318.1"
                     /translation="MSEKVNVKTVISFAGAYVATVIGSGFATGQEIMQFFSFYGFAGI
                     IGGIISMVLFSWMGASVMSKGKELQLKEPIKIYRVYCGKYLGIFFEWFGPLFLFGVFV
                     VMISGAGATLTEYYGLNPFVGRVGMAVVALLTVSLGLDKLSKILGGIGPIIIIFTLLV
                     GGISLAKNIGNIGEAAQVLSTVKIAKPVPNAYLSGVIYTTYNTIVVMAFLTGLGASAA
                     NKKEAICGGILGGVALMAAAIMMHLAILSDIGNLYSKAIPSLFLADKISPVIGVLFSI
                     ILILGIYTTAVPLLWSVTNRFVDDKHPKFKLITLIAAILGLIGGFLPFDKLVGILYPY
                     TGYMGVIILVCVLYRQITKTSGYQEGISDK"
     gene            95933..96349
                     /locus_tag="KOU88_000400"
     CDS             95933..96349
                     /locus_tag="KOU88_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210319.1"
                     /translation="MNVKFNIKGIIYGVIALVFVIGGFIFIPSMFVEKSKPIDYTVLQ
                     RNSIPEKILDVMDKYTNEERALAAKIDNKIYIIVTRGNNKYGIEMDKIESVVEEGKDV
                     LRVKIKYKDKEDSFPYIVVETNMSELPDRIELNATK"
     gene            complement(96531..97100)
                     /locus_tag="KOU88_000401"
     CDS             complement(96531..97100)
                     /locus_tag="KOU88_000401"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBK3210320.1"
                     /translation="MKKEFRKKVIESRKNKSANFVLSNSNLITEKLLQMEDIRNATNI
                     MLYLNFNNEVQTDNLIKKLLSLNKIVSSPITIKENHTLIPTQITDLKEGLRIGAYGIR
                     EPNEKSPTIDIKALDVVIVPAVAYDIHCYRLGYGGGFYDRFLENLRKDAITIGIAFDF
                     QIFDSIPKETHDAQLDYIVTETRIITPNN"
     gene            97254..98411
                     /locus_tag="KOU88_000402"
     CDS             97254..98411
                     /locus_tag="KOU88_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HBK3210321.1"
                     /translation="MYLVISKKKAIFLGVILVIITAMVTSAFQLTLGNKVVISKELYE
                     DYKKYDKLLGLESIIKQDFYKKVSDTDLVNGAAKGLFLGTNDKYSGYYTKDEMENLIN
                     DSEGSYVGVGMYIGASKDGGLVVVPMKDSPAEKAGVKSGDKLVKVNGKSVSYKNSDEA
                     VRMMKGKKGKTVELTILREDKQLNFKVKTDQIIEKSIESKVIDNDLGYIEITQFISST
                     YTDFDKALKELKAKNIKGLVIDLRNNPGGMLDICKEVADELIGEGTIVYTKDNKGNTE
                     YLKSDKEKLGLPIVVLTNGESASAAEILTAAIVDNKEGISVGTTTFGKGLVQSVVRLK
                     DGTGYKLTTAQYFTPNGDYINEKGIKPTIEEKDENKQLDVATKWLREQIDK"
     gene            99015..99497
                     /locus_tag="KOU88_000403"
     CDS             99015..99497
                     /locus_tag="KOU88_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBK3210322.1"
                     /translation="MYNNIKNILKENHITFEEYDHEPILSFEKAKEIREKLQYTGVES
                     KSLFIKDRSGNYYIFVTTEGKKLDPKTIKNVLGGKVSICSKEELTQKTQCLPGCVSPF
                     GYEKNISLVIDQDIFNHDKIIFSPGIPEKTFIITASGFKKVINNINNTTYKYIYINEF
                     "
     gene            complement(100196..101350)
                     /gene="nagA"
                     /locus_tag="KOU88_000404"
     CDS             complement(100196..101350)
                     /gene="nagA"
                     /locus_tag="KOU88_000404"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBK3210323.1"
                     /translation="MKSFIYADKFFMKHGIKEKGYLSIINGKFGEFQQERPNNTDNVI
                     DFSGKYIAPGLVDTHIHGLLGADVMDNTFEAINTISKGLLKYGVTSFLPTTLTDSVDT
                     LSDSVENISNSFNRVEGAKIQGIYLEGPFFTEKYKGAQNEKYFKDPDINILKLWQKKS
                     KNLIRKIAIAPERKGSIELTRYATKNNISVSLGHSSATFEQVKQVVNSGAKVFVHTYN
                     GMSPLNHREPGMVGAAMVLKDTYAELICDGHHVSPIAVKIMMDAKSSNNIALITDCMR
                     AGAMEDGKYTLGKFNVNVKNSVARLNSGSLAGSVLTMDKAVRNIVDWNISTLEDAIKM
                     ATYIPALSCNIDNVCGSIYQGMDADFIVTDNDFNIHETYINGICKYKVNK"
     gene            complement(101433..102158)
                     /locus_tag="KOU88_000405"
     CDS             complement(101433..102158)
                     /locus_tag="KOU88_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3210324.1"
                     /translation="MIKRNDKRPIYDQLVEILRTKIENEMEPNDRMLSERKICDEYGV
                     SRTTVRLAMAELEHMGYIYKRHGKGTFVAALSQNSQNLMESYSFTDYMRTQGKKPGTK
                     VLSFEVVESTKYFSEKLGITPGEKMIKIMRLRLADDLPMMLERTYLPMKEFIGLTKEK
                     IEQKPLYEIFREDYGEIIKVADEEFSAGIISDKEAKLLEVPGDSPCLKLLRTTYNDDN
                     IVIEFTLSVARSDKFVYRVRHVR"
     gene            102425..103354
                     /gene="pfkB"
                     /locus_tag="KOU88_000406"
     CDS             102425..103354
                     /gene="pfkB"
                     /locus_tag="KOU88_000406"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBK3210325.1"
                     /translation="MITVITFNPSIDRMYRVNNINIGEVQRVVSKNATAGGKGLNVAK
                     VCKILKENPLAMGFLGGFNGEFIKNELRKLDIQNKFTKIEQETRNCLNIIEDNKVSTE
                     FLEKGPIVEKSDLERFENDIEEVLKNTKILVASGSYCENMPIDYYEKIGNICRANNIK
                     FILDTSGEALKIALKSKPYLIKPNIDEIRHLLGMNIESREEIILSGKKLIEMGAENVC
                     ISLGKDGMVYLNEDNVYDVKVPVVKCINTVGSGDSTVAGFSVGILRGYKIENLLKFAN
                     ACGISNALNMETGFVDLVEIDKYQDLVEVKKLS"
     gene            complement(103483..104400)
                     /locus_tag="KOU88_000407"
     CDS             complement(103483..104400)
                     /locus_tag="KOU88_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK3210326.1"
                     /translation="MKNIKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREK
                     VCSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKILLNLGVHVYVDKPLASTVSQ
                     GEELIELSTKKNLNLMVGFNRRFCPMYKEIKNNATEIVSINICKHGLNSLRNVKFDST
                     LIDDYIHVIDTALWLANEDVEISGEDLFLTDNKNLIFVSHKLKGKNFSINTSMHRDSG
                     TKLEQVEILSKGNIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDC
                     IENNIKPAINGEECIKAQRLLEKIINSVK"
     gene            104871..106040
                     /locus_tag="KOU88_000408"
     CDS             104871..106040
                     /locus_tag="KOU88_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK3210327.1"
                     /translation="MKMFKLEEQKLKDLGAIITTNEIKQQPELWLETYEIYKSNKEKL
                     SRFIDTISNNHGQFRVIFTGAGTSAYIGNSILPYLKNKNDIRKYIFEAIPTTDIVSNP
                     YDYLKKDIPTLLISFARSGNSPESLAALNLGNKIVDNFYHLAITCNPEGELAKMTKND
                     ENNYLLLMPSKSNDEGFAMTGSFSCMMLSAMLIFDSLEDDVEKSYINAIIEMGRNVID
                     RKDEIHELINKDFDRVVYLGSGGLGGLTQEAQLKLLELTAGKISTVYDSPMGFRHGPK
                     SFIDENTLVFEFVSNCLYTRKYDLDVLEEIKRDKIAKFTCAVSVENENNFSGTKFEFK
                     EKYNKLPDVYLAMPYILFAQTIALFVSVKVGNKPDTPSATGTVNRVVKGVTIYEY"
     gene            106089..106940
                     /locus_tag="KOU88_000409"
     CDS             106089..106940
                     /locus_tag="KOU88_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBK3210328.1"
                     /translation="MALVTTTSMLKKAQDEGYAVGAFNVENMEMVIAVIEAAEELNSP
                     VILQTTPSTVKYAGLDYYLANAKVAAERVNIPVAMHLDHGSSFDLAMKALRSGYTSIM
                     IDGSHESFENNISISKSVVKACSPSLIPVEAELGKVGGKEDDLDGGNSNDYTNPKEAK
                     EFVDRTGISSLAIAIGTAHGLYKGEPKIDLDRLSEIKNVVSIPLVLHGGSGIHDDIIK
                     EAIKRGIAKVNYATELRIAYSKGVKKVLDEDSEVIDPKKYGLAGLQSVKDFVKEKIKV
                     CGSVNRV"
     gene            107266..109167
                     /locus_tag="KOU88_000410"
     CDS             107266..109167
                     /locus_tag="KOU88_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3210329.1"
                     /translation="MRERIILETLKNSSGYLNIDYFADKLGVSTRTIRNEIKKIETIK
                     ECNGFKLEYKSKLGYILNIKDQDKFEHYLRNLPSDLVENPEQRLESIIVELLVNEGYK
                     TIEQLSKKFLVSSSQIKNDLKKIDEKIKDTELKLERKAHYGIKIEGSIKEIQSILVDS
                     YFRGNRNITEYRNKFIDNLKLANIRSTIKNVLNEHDLEANLTELEEILAQIIILYIRV
                     SMRVVGNASDLKLYTEDLIIDKLLDKIFRDKKYNLNYDEKYYLKELIKLKTKDKKATI
                     KNIDKNKLQDIMFEFFREIDKKYNSNFLEDKEFFNLFYLHIACLIERIKKNHKIINPF
                     SVKISQQYPTVFNLSIQFSKIIENEYHIKISQDEIGFIATHIAVPFEKREEANFNKKY
                     KIAIICSSGGGSAFLINLRLKEIFPNAEIRNFSLLEEKAVIEFAPDLIFSITNLLFEI
                     NAPVILINEILDELDYLDIKESVRFADHIGNISSPKQYILGLFDKNHFRCIKDKAKYK
                     DILDSMSKCIVDEGACSPTYPKDVWERESYLSTIYTNGVAIPHPIEMTGNKNIISVAL
                     IQTDIIYENRVPKIIFMISLIKGNLELHKQISKYLSKIMANKDMVDMLNKSQSYEEFM
                     YKLKIYLGG"
     gene            109170..110213
                     /gene="ypdE"
                     /locus_tag="KOU88_000411"
     CDS             109170..110213
                     /gene="ypdE"
                     /locus_tag="KOU88_000411"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBK3210330.1"
                     /translation="MNIEFFKRLSEADGIASNEEEVRHVLLEELKAYSDKIICDGLGS
                     IIFSKIKDESAPNVMICAHMDEVGFMVRSIDKLGMIHLITIGGVKPLAQFVQKVRITT
                     KEGKKIPAVINATYNNGKAENIYADIGAYTEEDVYNLGINVGDMVTYTTSFEEFTLPD
                     RLVGKAFDDRIGCFVMGEVLKELRKENLNCNIHFAATSSEEVGIRGAKTSTQLINPDI
                     VFVIDVACAKNEFVRDYTNQKQIDKGVMLMHRDRTLVPSRKMIDYVMEIADKNNIPLQ
                     HDMFESGGTDGGEAHLVNEGKPCVVTCVPVRYGHCAFSIVSNKDLENIIRLYTQLILN
                     FDEEQYKHIRNFI"
     gene            110228..110533
                     /locus_tag="KOU88_000412"
     CDS             110228..110533
                     /locus_tag="KOU88_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK3210331.1"
                     /translation="MSTEVQIMELISTAGESKSKAFEALKKVKSKDFKGAKLLIEEAR
                     KIDIEAHRIQTELITQDLNEDVESPAMSLLMVHAQDHYMTSQLAKDLIEALIYCLDK"
     gene            110630..110965
                     /locus_tag="KOU88_000413"
     CDS             110630..110965
                     /locus_tag="KOU88_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210332.1"
                     /translation="MKILLCCAGGFSTNMLMQNMKKVVKESAKLNEKDFEFTAIPADS
                     IESEVDDWDIVLIGPQIAHKIDFLKGILEPKNKPFAVIDKDVYGKMDGATVMKLALIT
                     YKKHQLAQG"
     gene            110997..112319
                     /locus_tag="KOU88_000414"
     CDS             110997..112319
                     /locus_tag="KOU88_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3210333.1"
                     /translation="MFSKFEAFMNRVFMPLAHKVDNQRHLGSIKAGMVAMTPFTILGS
                     IFAILPALPNMLGENNPISKFILNNSAILDLPVSLSIGLIGLYACMCIAFNLGNYYKL
                     YIPGCVALSTFSFLFLVASFTPDGALEIGNLGAKGLFTGMIAGLGSVELYNFCNKKNI
                     TIKMPENVPDFVSRSFELIPTTIIVCGTFIVARFISLKVFGELPPQILTQFLSPLVGS
                     MDNPWSVLALNFAICTIFFFGIHSSVFSPITRPIMITFIAENIAAMQAGETIPHFFTA
                     GASSAFFGFTGCGISIGCVIACMLSKNASYKKIGRVSLFPALFGINEPILFGAPIILN
                     PIMFIPHVFGGAIIGTLPMFFMHWGWLAKPVFDPPYVGVFLEGFLTNGDWHSILANAL
                     QLVLAVLLYWPFFKIMERQQNNKKQKEETKNIFSKEEEDLLDDLGLDF"
     gene            112329..113399
                     /locus_tag="KOU88_000415"
     CDS             112329..113399
                     /locus_tag="KOU88_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK3210334.1"
                     /translation="MNNTMERLVSLIYKRGVDALLIKAKNTKRYIGALSGSGVYVLVT
                     KDKNYQILDGRYIDEADKKTTGFIKRIVSQGSYIPTIIELLKELNIKKLAIENQAMSI
                     QEYLSLKNEGFEINLITNELWKLRAIKSKEEIELIKKACEITDEVFDEVISEIKKDMT
                     ELEVSALIQYHALKKGASGMSFETIVVSGERGAMPHGRPTNKKLKVNEAITIDFGVVY
                     QGYQSDMTRTISIGKPPKIIKEIYDVVLEAQLSAIESIKEGTRASDVDKVARKIIDKH
                     GFGEYFNHGLGHGIGLGDGEVPTLNPNSEDILVEGMVMSCEPGIYIPNVGGVRIEDDI
                     VIIDGKGVPLNKTSKEFIILGE"
     gene            113404..114591
                     /locus_tag="KOU88_000416"
     CDS             113404..114591
                     /locus_tag="KOU88_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3210335.1"
                     /translation="MKYNFNKVLNRKEGNCRKWSNHVIKEKFGLNEDAIPMDLADIDF
                     ECAPAIKESILKRASVGDYSYTFIGDDFYDAIINWNKRRFDVYIEKDWIKLTFGTVST
                     LHYIVQAYTKEGEGVLINTPAYDPFAEAVVNNNRKLCCSSLKLDNNRYYLDLEDMENQ
                     MKYENIRLLIFCSPQNPSGRIWTKEELYQVSELCLKYNVILVSDEIHRDIIFKDYRFV
                     SLWNAHPEIYKNSIICVSPNKGFNLGGLKTSYVLIRDVKIRETLLERLKSNSITSPNV
                     FAIPAIVAAYNESEEWLDAMTSYVEENFEIVYDFFETNIPKAKVMKSDSSFLAWIDVR
                     EVFRNEEESKEFFRHANLTMVVGSYFVKDGDGFIRINVGCPRETLNEALNRIKKTYIS
                     MYC"
     gene            complement(114788..115660)
                     /locus_tag="KOU88_000417"
     CDS             complement(114788..115660)
                     /locus_tag="KOU88_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBK3210336.1"
                     /translation="MNILQNENLIIESSSFGAELTKIFSKKYDKNILWDGNKKYWGRQ
                     SPILFPIVGKLFDNETIIEENLYSMTQHGFARDMDFEIVDKGDTFVTYKLTDNESTLK
                     KYPYSFELIINYTLNDNSIEVEWIVKNTDSKDIFFSIGGHPAFNLPFYEQNDFSKHYL
                     EFKSKNDVEKINLNGSFTDDIIPIGKLKNLQLNPEVFKNDALIYTNIDEVSICNNDGS
                     KYVTISMEDFPLVGIWTPYYSETNSTAPFLCIEPWYGLADSINSNKIYKDKKFINKLS
                     KGKVFTASYNINIH"
     gene            complement(116054..116245)
                     /locus_tag="KOU88_000418"
     CDS             complement(116054..116245)
                     /locus_tag="KOU88_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210337.1"
                     /translation="MDDFSKLKSLYEDGYRCIYHDCVDNNYTIYLKNFYTEGSETIEL
                     SSESDFSQFKDYIDGLRMS"
     gene            116465..117511
                     /gene="cobT"
                     /locus_tag="KOU88_000419"
     CDS             116465..117511
                     /gene="cobT"
                     /locus_tag="KOU88_000419"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBK3210338.1"
                     /translation="MSLLESISKNIYSLDNSSIEKTKQRLDRLIHPTGSLGKIEDICM
                     QLAGIFGNENFDTSKKVIIAFAGDHGVYEEGVAPDPQNITKLQFPNFSKGLCGVGVIS
                     KFVGADVVAVDVGINCDEKLDGVLDYKIRKGTSNMAKGPAMSKQEAIRCLEIGIEIAE
                     QCIEKDYKVIGIGEMGIANTTPSTAIISVISGCDPLEVTGIGAGLKKERLKHKAEVIR
                     KAIEINNPNPTDGVDILSKVGGFEIGSMAGVILGCSANRIPVVIDGFISYAAALIAYK
                     INPKTREYMIASHLSAESGTKRALDILKLDPLLNMDMRLGEGSGAALAFDIIEASNYT
                     YKNMATFDEIDMGR"
     gene            117543..118103
                     /gene="cobU"
                     /locus_tag="KOU88_000420"
     CDS             117543..118103
                     /gene="cobU"
                     /locus_tag="KOU88_000420"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBK3210339.1"
                     /translation="MSKIILVTGGARSGKSNFAEKLCFDRNNNTAYIATSIPFDDEMK
                     DRVKKHQENRPRNWNTYEIYEDIYSIIKEIYKEHETVILDCVTLLVNNLMFEHNLNIE
                     ESSQEEINKLEQYIKEQVVKLIEEIEKTNLYFVFVTNELGMGIVPGNKLSRIYADIVG
                     RINQYIASKSNEVYFVVSGIAMKIKE"
     gene            118113..118886
                     /gene="cobS"
                     /locus_tag="KOU88_000421"
     CDS             118113..118886
                     /gene="cobS"
                     /locus_tag="KOU88_000421"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBK3210340.1"
                     /translation="MKRFILILQFLTRIPIKLNVGFDDEFYKSIVYFPLVGFVIGILS
                     YLIGWISMLLFEPFIASIIITLAGVLITGGLHIDGLGDTFDAIYSYRDKEKMLEIMKD
                     SRLGTNSLLAIMFVLLLKVGFVYDIISNNSLWVIIFMPMIARLGVMLLTYKTVTPREK
                     GMGNLFIGKLTTSMLITAIIYTLLIVALITKFIFLLPNIVLIKVLGSIIVVFVFIILF
                     KKHIYKKIDGVTGDILGCGIELSELVYLIYIYLLIFMFF"
     gene            118906..119520
                     /locus_tag="KOU88_000422"
     CDS             118906..119520
                     /locus_tag="KOU88_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK3210341.1"
                     /translation="MIRLILIRHALTNDNKKGRLSGHINSCISEEGKLQINKITRYLS
                     NENIDKVYTTPSTRTKDTVEKISKLKLLEIEEKEALREISFGDFEGRTFEEIKIKYPN
                     EFEKMIKEGNNYRYPNGESLIDSYKRVAKEIDNIILENDSNLDTKTILICSHAGTIRN
                     IITHLISGSYKYHWNFKIDNASITVLEIDGGFAVIDKMNFTDFI"
     regulatory      119587..119766
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            119896..121395
                     /locus_tag="KOU88_000423"
     CDS             119896..121395
                     /locus_tag="KOU88_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyric acid synthase"
                     /protein_id="HBK3210342.1"
                     /translation="MLQGTASNVGKSVLVAGLCRIFKQDGYTVAPFKSQNMALNSFIT
                     KEGLEMGRAQVFQAEAAKIEPIADMNPVLLKPSGNNKSQVIVRGKVVGEMPSSKYHDY
                     KLELVDVLKETFNSLNSRYDIVVMEGAGSNAEINLKDRDISNMGMAEIADAPVIIVGD
                     IDRGGVFASLAGTMLLLNEDEKRRVKGVIINKFRGKKELLQDGVKMLEDIIKVPVIGV
                     VPYTDIKIEDEDSVTTRFKKKMNKSDIHIEIIRTPHMSNFTDFNIFETQEDVSIRYVD
                     YGESLGNPDILIIPGTKSTIDDLTYIRKSGLESQIKNLHSQGKLIFGICGGYQMLGKK
                     LKDPYHVESEIEEVDGIGLLDTETTFEKEKTTTQVEATIVECISEYMNNLKGKKVKGY
                     EIHMGITKRGNDVRSLDLITKKLDKEVNYTEGSVNKEGNVIGTYLHGIFDEISFTRAI
                     LNNIRKKKGLGELESKVNSFNEFKDKEYDKLADFLREHLDIEKIYEIMK"
     gene            121434..122810
                     /locus_tag="KOU88_000424"
     CDS             121434..122810
                     /locus_tag="KOU88_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobyrinate a,c-diamide synthase"
                     /protein_id="HBK3210343.1"
                     /translation="MKKILIAGTNSGVGKTTISLGIMQALVKRNMKVQPYKVGPDYID
                     PSYHTFITGRHSRNLDSYMLDDEKIKYIVNKSSKDADISVIEGVMGLYDGFGIDLDNC
                     TSSHTSKVLKSPVILVINGKSMAASSAAMVLGYKELDKDVNIKGVIVNNVKTNSHYQI
                     IKSSIEKYCNVEVLGYFPPNNKFSLESRHLGLVPSVEMKSLREKFYTLADEIEHYIDI
                     DRIIEISESDEFESDFDFQTLIENNKIKEHVNNKSIAIAYDKAFNFYYRENIELLEEL
                     GLEINYFSPLEDVSVPNADYIYIGGGFPEIFGKELEANESMRTSILEAHNNNIPIYAE
                     CGGLMYLGEKLLNQEEQEFNMVGIFSGISKMTSSLKRFGYCIGVAKENTLLSKKGESI
                     KGHEFHHSIFESDEKCVYSMRKERDGNIVEEWDGGYSKGNTLATYLHTHFYNNLNCIE
                     NFLKKGNE"
     gene            122811..123782
                     /locus_tag="KOU88_000425"
     CDS             122811..123782
                     /locus_tag="KOU88_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBK3210344.1"
                     /translation="MSILSIYIGYVTDLIVGDPYSFPHPVRFIGKLINFTQGIIRKVS
                     KNDRQLKLGGFILWFITVGITYLTTYAIVKLFSFNILLSIVVNSFIIYTTLATKCLKD
                     EALKIYNVLKTEDIEKSRIQLSYIVGRDTTNLSEPEIIRATVETVAENTVDGIIAPMF
                     YAFIGGAPLAMAYKAINTLDSTVGYKNKKYKDIGFASAKIDDIANYIPARISVILMTI
                     GSFFLNYNYRNCFKISIRDRKNHKSPNCAFSEGAVSGALGIQLGGTNVYFGEKVYKPT
                     IGDKLREIDKEDIIKTNKIMYASSFVSMLVFTLIYVLCRMILINLII"
     gene            123814..124884
                     /locus_tag="KOU88_000426"
     CDS             123814..124884
                     /locus_tag="KOU88_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBK3210345.1"
                     /translation="MKDLGHGANVDEMARLYGKNPKEIIDFSSNINPNVLPNLERYIL
                     KGLEECRNYPDINYTNLRENISKYIDINPDFIIPGNGATEVIYLLMKSIKKKLAIINP
                     TFSEYRRSAELNNLDIIDLELDLENNFKLNIDIIKENIKRFDSLFICNPNNPSGNVQD
                     LKELVHLLDKHNKVLIIDETFMEFVEDESKYSLVKYIESNKNIFIIKAVTKFFGMPGL
                     RLGYGLTSNTEIMNKIYEHKEPWTINSFADILSNFIFEDKEYIKNSKEYYIEERKYML
                     QELRNIRNIKVYDTDANFILIRIYKKTTKELKKDLFKQGNILVRDASNFIGLDDSFIR
                     VAIKSHEDNKILIENMKNLLGD"
     gene            124886..125773
                     /locus_tag="KOU88_000427"
     CDS             124886..125773
                     /locus_tag="KOU88_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein"
                     /protein_id="HBK3210346.1"
                     /translation="MKSYGICPASCGEFVQGIIDDEEYLCSYAIDMYSKVYIEEKLVD
                     INLGRYKSRLAIEKVFEKFNLPKKYTKNISLNINSKIPVGKGMASSTADIGATIKATL
                     SLIDKDLSSEEISKLAAEIEPTDSIFIDKNSIFNPLNGTVIKYLGNLTNAKVVILEPN
                     KVLDTMKIRLRQDYNKLKVENKEVIKKSFALLEEGLKKNNLSLVGEACTLSSLANENI
                     EKKEYLNEIIKISKKYGAYGVNIAHSGTVVGILIDKSMNDKKMIDALCESNINSVYNK
                     IYTQNIINGGIKGEIEWNT"
     gene            125761..126393
                     /locus_tag="KOU88_000428"
     CDS             125761..126393
                     /locus_tag="KOU88_000428"
                     /EC_number="5.4.99.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003724727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-8 methylmutase"
                     /protein_id="HBK3210347.1"
                     /translation="MEYIKNPMKIEEKSFELIQEIIDEIRPDYKFKNNIEEKIIKRAI
                     HTTADFDYLDILKISEEAVDSIIDALKNNASIYTDTNMALSGINKRKLESLGCKYKCL
                     VADDETVKLAKEKGITRSMAAVEIAAKEEGRKIFVLGNAPTALYKVMEMKSEGRLDLD
                     AVIGVPVGFVGAQESKDEVEKTDIPYIISKGRKGGSNLAAAIVNAILYTM"
     gene            126402..127628
                     /locus_tag="KOU88_000429"
     CDS             126402..127628
                     /locus_tag="KOU88_000429"
                     /EC_number="2.1.1.195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-5B (C(1))-methyltransferase"
                     /protein_id="HBK3210348.1"
                     /translation="MEEYVYIDGKKYRRGYTTGSCATGASKAAVYMLITKNRINTINI
                     DTPKGIPLLLKVDNINISDTFVECSIKKDGGDDIDATHTMDIYARAEIVAKNDKNKGY
                     LTLKDIDSLSTNSECKSELYKFIRVYGGTGIGVVTKKGLSVDVGKPAINPTPLKMINH
                     EIRKLIGDNFESILGNDKVLKITIFAPQGETVAKKTFNPRLGIVGGISIIGTTGIVEP
                     MSDEGWKKSLSIELQMKKEQGLDKIILVPGNHGEQFIREKLNLDIKYVVRVSNFIGYM
                     IKEAQRIGYKKILMAGHIGKFIKVSAGIFNTHSKVADARSEILVANLALMGARYEFLN
                     KINQCVTTEEAVELINNSEYREVYNILSNKCRERVKQYLNEDSDDIDVEVIIFSMDKS
                     LLGKSDNTDDLVEVFI"
     gene            127625..128233
                     /locus_tag="KOU88_000430"
     CDS             127625..128233
                     /locus_tag="KOU88_000430"
                     /EC_number="2.1.1.289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-7 (C(5))-methyltransferase"
                     /protein_id="HBK3210349.1"
                     /translation="MINIIGLGPGNLDYITKKGENLISTSDVLIGGKRNLESIKNFEG
                     EKIVLDSNLREIIEYINNNKEKQISIIASGDPLIYGIGRYLSKNIDNKMLNMVSGISS
                     LQYIFSKIYVDMNDVYITSSHGKVPDFDYILSHKKVCMVTDSKIGPKQISREIIDRNL
                     NKIIVVGENLSYDNEKITIAKPEEIIRIDNFDMNVVVILDEE"
     gene            128223..128798
                     /locus_tag="KOU88_000431"
     CDS             128223..128798
                     /locus_tag="KOU88_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating cobalt-precorrin-6B
                     (C(15))-methyltransferase"
                     /protein_id="HBK3210350.1"
                     /translation="MRNSEFITGKVPITKEEVRAISISKLNLVNAKNLIDIGAGTGSV
                     SVEAAYNYPNLKVISIEKNDDAIELIEKNKKKFNLKNIEVIKGYAPINLGLNVKVESI
                     FLGGTGNNLEEIIEWSKKNLVTGGRLVANFIIIDTFNQTLKLLKKHGFKEIDVCVLNV
                     SKLEKLGKGEYFKPLNPIYIISCEKGENDDE"
     gene            128791..129543
                     /locus_tag="KOU88_000432"
     CDS             128791..129543
                     /locus_tag="KOU88_000432"
                     /EC_number="2.1.1.271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin-4 methyltransferase"
                     /protein_id="HBK3210351.1"
                     /translation="MNKVHFVGAGPGDKELITLKGYKLLSNADVVIYAGSLVNPELLE
                     YCKEDCQIHNSAHMDLQEIIDVMREGIENNKSVVRLQTGDFSIYGSIREQVEDLNKLN
                     IDYDCTPGVSSFLGAASSLGVEYTVPEISQSVIITRMEGRTPVPEKESIQSYAKHQTS
                     MVIFLSVQEIEKVVSKLLEGGYPKDTPIAVIYKATWADEKIVKGTLSDIAVKVKENNI
                     NKTALIMVGRFLGEEYNNSKLYDKDFKHEYRG"
     gene            129527..130648
                     /gene="cbiG"
                     /locus_tag="KOU88_000433"
     CDS             129527..130648
                     /gene="cbiG"
                     /locus_tag="KOU88_000433"
                     /EC_number="3.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-precorrin 5A hydrolase"
                     /protein_id="HBK3210352.1"
                     /translation="MNIEGNIAIICITENGKKLALKINSLVNNCVIYQVKNKKSNLVV
                     EETCVHTVQKKLSDFVGEIFSKFDYIVFIMATGIVVRSIAPYIISKFSDPAILVMDEK
                     GKNVISLLSGHIGGANSLTQYISSLIDANPVITTATDINQKASLDMIAKKLNAHIDNF
                     RESVKEVNSMLVNNKCVGLYIDEGYQVDTRGFKLIESKDELRDSFSNTYIEKLVVVSN
                     KINCIEDIENLNLDNKFEHCYSTKKIIKVIPRDIVIGIGCRRNTDSELMYNSLEEFLN
                     KQNIDIRAINTVGSIELKKDEKAIIELSKILKVPFKTFSVDEISKVDNLFDKSDFVKK
                     NVGVYSVAEPVAYLLSKGNLLVEKHKYKGITFSVGRIKI"
     gene            130645..131370
                     /gene="cobJ"
                     /locus_tag="KOU88_000434"
     CDS             130645..131370
                     /gene="cobJ"
                     /locus_tag="KOU88_000434"
                     /EC_number="2.1.1.131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011701973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-3B C(17)-methyltransferase"
                     /protein_id="HBK3210353.1"
                     /translation="MIYVVGIGPGSKDTMTLEAIKAIEDSEAIVGYKTYIKLIEEFIQ
                     DKEIIQNGMRQEVDRCKQAVEEAKKGKKVAVVSSGDAGIYGMAGLILELISKEDEDIK
                     VKVIPGVTASIGAAAILGAPIMHDFCHISLSDLMTPWEVIEKRLRLAAEADFVICLYN
                     PRSKGRSEHLSKAFKIMGEFKSGDTPVGVVKDVGREKEEKLVCTFENMDFEKVDMTTM
                     VIIGNKSTYINGELMITPRGYTV"
     gene            131367..132119
                     /gene="cobK"
                     /locus_tag="KOU88_000435"
     CDS             131367..132119
                     /gene="cobK"
                     /locus_tag="KOU88_000435"
                     /EC_number="1.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="precorrin-6A reductase"
                     /protein_id="HBK3210354.1"
                     /translation="MILILGGTSDSLSICDKINELKNQPYILSVTTDYGRELAQQHAE
                     NVILGKLGKEDMLKFIKDNNIVKIIDATHPYAVEVSKTAITCAKLLNIDYIRFERKSL
                     IEEIDYDNKFIVDTIEEACEIANKIGTNIFIGTGSKNLNRFIEEISDKNLVVRVLPTS
                     EVILSCEKLGLSADNIVAMKGPFSQYINEETYKHYNIDLVITKESGIAGGFLEKVNAC
                     KTFNIPVIIIKRESINYENVFNDINKIKDILV"
     gene            132138..133616
                     /locus_tag="KOU88_000436"
     CDS             132138..133616
                     /locus_tag="KOU88_000436"
                     /EC_number="2.1.1.151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt-factor II C(20)-methyltransferase"
                     /protein_id="HBK3210355.1"
                     /translation="MKKALLVVSFGTSYHETREKTIDICEDKIKNSLKSHDFFRAYTS
                     NMIINKIKKRDGIEIDNPIQALDKIYEQGYDEVIIQTLHIICGEEFNKLKEQVDGYSS
                     KFKKIVLGRPLLTHIEDYQEAVEAIKHQIPHMESNEAVVFMGHGTLHESHSAYPALEY
                     MLRDNGINAYVGTVEGYPEIEHVIRRLKEGNIKTVNLMPFMLVAGDHAINDMAGDEED
                     SWKTILEENGFNVRVHLKGLGENSYIQDKFVRHAVKCAENAKFYGIGAGPGDGSLLTI
                     KAVNTLKKLDILYTPESKKGGDSLALSIVSEYLPESVEIKSRHFPMSFDGNEKSLAWD
                     NVAQEIISDVNDGKNVGFVTLGDPMIYSTYVYIMKRILGEVEVETIPGISSFSNIASN
                     QNFPLVMDKEALVVIPCTMEDDKIEYALQNYNSIVLMKVYKNFKEIIKKLEKYDLIEH
                     AILVSNSSQESENVFTDLKEAHLEDKISYFSTILVNKDNKIK"
     gene            133646..134551
                     /gene="hemC"
                     /locus_tag="KOU88_000437"
     CDS             133646..134551
                     /gene="hemC"
                     /locus_tag="KOU88_000437"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBK3210356.1"
                     /translation="MNIVVGTRGSNLALIQTEWVINELKKKYPEISFEIKIIKTKGDL
                     IQNVSLDKIGDKGLFVKEIEQQLLDGKIDIAVHSMKDMPSYLADGLKFAHTPKREDPR
                     DVLILREGYKNLDDLPHGAVIGTGSKRRKFQLLKQRPDLNIVQVRGNVETRIRKIKDE
                     NMHGIVLAASGIIRANLQDKISSYLPVDVVIPAPAQGALAIEIRSNDSTIEGIVNSLK
                     DENTEIQILAERGFLDGVNGSCHIPMAAYCEIIQDKIHLTGLYGDSEGKKVVIKSIDG
                     DISSPRELGLKLAKLVLKEYENYEG"
     gene            134541..136040
                     /gene="cobA"
                     /locus_tag="KOU88_000438"
     CDS             134541..136040
                     /gene="cobA"
                     /locus_tag="KOU88_000438"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBK3210357.1"
                     /translation="MKGKVYLVGAGPGDYKLMTLKGLECIRKSDVIVYDRLANSSYLR
                     EAKPDCELIYVGKASSNHILPQEDINRIIAEKAKEGKIVTRLKGGDPYVFGRGGEEAE
                     TLVDEGIEFEVVPGITSAIGGLCYAGIPITHRDHASSFHVITGHLKGDDSGELNWNAL
                     ANNKGTLVFLMGISNLEKISENLMKEGKDKDTPVALISWATRYNQRVVTSTLENVYET
                     AIKEEVKPPTLIVVGSVVGLREKLNFFESKPLFGKSIAVTRSRNQNSVLVEKIMDLGG
                     NPIEIPTIKVEKIQNNINLENEIKNINKYNYLILTSKNAVEIFFEKIYEMNFDLRILS
                     NLKVCAIGSATSNELKKRGIIADIVPKKFVAESLYEELAPILNDDDNILIPRAENARD
                     YLVDKLKAICEVTEVHIYRTVIDEEKKGEILDILNSNDIDYITFTSSSTVNNLVEIIG
                     KENIKILEKIKTLSIGPITTETINSLGIKLYKESATSTIDSLVDLIIKN"
     gene            136057..137022
                     /gene="hemB"
                     /locus_tag="KOU88_000439"
     CDS             136057..137022
                     /gene="hemB"
                     /locus_tag="KOU88_000439"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBK3210358.1"
                     /translation="MLRRPRRLRASKAIRNLVRETKVNVEDLIYPLFVVEGENIKEEI
                     KSLPDVYHLSIDMLEDEIKEISELGIEHIMLFGVPDEKDECASQAFNDNGIVQKAIRK
                     VKEINSDINVITDVCMCQYTSHGHCGILTDTGYVDNDKSLEYLAKISVSHAKAGADMV
                     APSDMMDGRIQAIREALDENGLENVGIMAYSVKYASNYYGPFREAAHSAPSFGDRKTY
                     QMDPANSNEAIIETELDILEGADILMVKPALSYLDIIRRVKDNFDLPLAAYNVSGEYS
                     MLKFAVKEGLLNEDVILESITSIKRAGADIIITYFAKDIAKLLKK"
     gene            137175..137753
                     /locus_tag="KOU88_000440"
     CDS             137175..137753
                     /locus_tag="KOU88_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional precorrin-2
                     dehydrogenase/sirohydrochlorin ferrochelatase"
                     /protein_id="HBK3210359.1"
                     /translation="MLYPINLKLDELDVVIIGGGEVAYRKCKNFLEFNKNVTIVSKQI
                     LNKFYDLKGNIKIIKDDYKEIYIKDASVIIAATNNRELNMEIGLYCKAKNKLVNVVDN
                     IEISNFTVPSYIKRGDLLISVSTGGKSPSLSSKIKKEIEERYTEDYEEYLNVLGDIRK
                     KVIKKYEDKSKRKDVLNMLVTLDLEELKKFDI"
BASE COUNT        55131 a        14766 c        24991 g        42913 t
ORIGIN      
        1 ttctataaac ttattaaaaa cttaatagaa atattaagca taaagattat gtggttacaa
       61 tagcagagag gatacacctg ttcccattcc gaacacagaa gttaagctct ctagcgctga
      121 tggtacttgg tgggaaactg cctgggagag taggacgtag ccacgtaatt ttttttattt
      181 tttgtcaaaa aaaacaaaaa atacgtattt cttttttcat ttcgggaaaa ctaaacacag
      241 gaattatgga ctttataaaa atttaattct tgaggagtga tataagtgaa aaaagttgct
      301 ttaattttag ctataatagg tgcgcttaac tggggtgcaa ttggtattct aggtacagac
      361 ttaataggta gtatctttgg tggaacatat gaaatggtaa gtagaataat atacttcatt
      421 gtaggtttag ctggattata cttaatacca agtttaatgt ctgatgatag agaataattt
      481 atgcttttat gttaaatacc tcattctaaa tgtttagaat gaggtattta attttataaa
      541 aatattaatt tgtttctttt ttaatggtaa aatagataag aattgaagtt ttaaaaagaa
      601 gtattatgta aaaaaggagt actattaata tatgtttatt attaatgaat taaataagat
      661 tgtaaatgaa gaagtaatat cttttcatat gcctggtcat aaaaagggac aggtttataa
      721 aaagttagga tataaagata tactaaaaaa tttgtataaa atggatacaa ctgagatatt
      781 aggaacagat aatttacact ttccggaagg aattataaaa aattcacaaa aaaaagcatc
      841 aagagtattt aaaagtgatt atacttgcta tttagtaaat ggtagtagct gtggaataca
      901 atctgcaata atgtcagtat gtagtcctaa aagtaaaata ataacaaata gagactgtca
      961 tcagtctgtt ataaatggat gtattttagg agatatagat atagagtatg tgccttgtga
     1021 gataagtgaa gagacaaata tcttaaaagg gatatctata agtaatgtga ttgatataat
     1081 agataaaaac ttggatgcaa aagcagtact gcttacttat cctacatatt atggaatgac
     1141 atatgattta gaatacatat gtaattatgc acatagcaaa aagatggtag tgatagtaga
     1201 tgaagcacat ggtgcgcatt tagggcttag cgagaggctt cctaaaacag ctcttgagca
     1261 aggcgcagat atagttgtac agagtacaca taaaactctt ccagcattta cacaatcgtc
     1321 aatgatacat atacagggag accgagttga tatagataaa atattgaaca tgttaagaat
     1381 tacagaatct tcaagccctt catatttatt attatcttct ctggaattag cagtagatat
     1441 atatgaaaat aaaggaaaag aattaatgga agagctttta aataatatta taactttcaa
     1501 aaataaagtt gattcaaata ttaatatata cgacacaaat gataaaacaa aaatatttat
     1561 atcatctaaa aacatgggtt taacaggtta tgaactagaa aatattttga gaaataaata
     1621 taacatacaa gtggagttat ctaattatta tggagttctt ttaatatgta caataggaaa
     1681 tactgttgag gatttctcta gtttagaaac agcattaaac aatattgtaa aggaagactt
     1741 taaatttgaa aagttagaaa ataaaaaata ccctgttgtt attccaaaga aaatattaac
     1801 acctagagaa gcattttata aaactaaaaa aagtgttaaa atatatgaca gcataggtaa
     1861 agtttgtggt gaatgtatag ttccataccc acctggaata agtgtaatat ctcctggtga
     1921 agtaataagt aaagaaataa tagactatct aatgttttgt cattctaaag gcatgattgt
     1981 gagtggattg aaagatgtag atttaaattt tatacaaata atagatttag aagacattta
     2041 aaaattatga tataaaagta gatagaagta gatagtttaa aattgtgaag agaaataaat
     2101 agactgctta tatagagcta tctaataaaa gtactaaaaa agtaaaaagt gtttgtatgg
     2161 aggatatgaa aatgaaaggt aagttaataa ttatagagag tggttcagat gcaagtggaa
     2221 aggctactca gacagaaata ttatatgaaa gattaaaaaa agaaggctat atgattaaaa
     2281 aggtagaata tccaaattat gaatctccat catctgcctt ggtgaaaatg tacctaaaag
     2341 gagactttgg taaaaatgca tcagatgtag acccatatat agcatcaact ttttttacag
     2401 ctgataggta tgcatcattt aaaaccgatt gggaggagtt ttacaatgaa ggtggaataa
     2461 ttatcgcaga tagatataca acctctaata tggtacatca ggcctctaaa atggatattt
     2521 gtgatagaga agagtattta aattggttag ctgattatga atttaattta tttaagatac
     2581 cacaacctga ttgtgttata tttttagatg tgcctattga atttagtaaa aagcttatgg
     2641 agaatagaaa aaataaaatt acaggggaag aaaaaaagga tattcatgaa agtgacatag
     2701 agtatttaga gaaatcttac aacaatgctt tatatatagc agataaatat gattggaaaa
     2761 aaataaattg tgttttagat aacaaattaa gaagtattga aagtatacat aatgaaattt
     2821 ataaaatagt tcttgattca ataaaaccta tggagagata aatatgtatt ttgaaaatat
     2881 tatagggcaa gattttgcaa agaaatattt aacaaattct ataaagaaaa ataaacttaa
     2941 taatgcgtat atgtttgaag gaatggatgg aataggaaaa aagaaatttg cagatgaatt
     3001 atcaaaacta ttacttgatt atgaaaatct cgaaaatagt ccagactatg tactcataaa
     3061 accagatgga aatagtataa aaatagctca aatcagaaat ttacaatcag atatagtaat
     3121 aagacctcat aaagactata aaatatatat aatcaataat gctgaaaaaa tgactgtgga
     3181 agctcaaaat gcacttttaa agacgctaga ggaacctcca aactatgcta taataatctt
     3241 agtcacaaac aacaaggaat ctttattaga aactataaaa tctagatgtg atataataaa
     3301 gttctcacct ataccaattg aagacttaaa acgttatttg ataaatacag gtatagaaga
     3361 agaaagagct caattattgg ctattttttc gagaggaagt attgagaatg ctctaaatct
     3421 atctcagtct tctgagtttt caatgatgag agaagatata caacagtata ttcagataat
     3481 gttagataaa aacatagtgg agattttaaa tataccaaat aatatggaaa aatatagagg
     3541 taagattata gctttattag atatgatgat aaactatttt cgagatatca tcctattaaa
     3601 agaaaatgta aacaagaaca tgttaataaa tgtagataag ctagttttca ttcaaaatat
     3661 gagtggaaaa attagttatt ctcaattgtc caagattatt gatataatag aagatgcaaa
     3721 gagtaaaata aaaagcaatt gcaatttcaa tataagcata caagttatgt ctttaaatat
     3781 atacgaggtg attaaatgat aaagatagta ggtataaggt ttaaaagtgc tgggaaaata
     3841 tattattttg accctgttga ttttaatata gagcaagata tggatgtagt tgtagaaact
     3901 gcaagaggct tggagtatgg gaaagtagtc gttggtccaa aagatatgga tgaaagcgaa
     3961 ttagtttctc ctttgaagcc aattataaga atagctacag aagaagataa aaaagtatat
     4021 ctagaaaata aggaaaaggc aaaagaaact tttgagttgt gccaacaaaa aataaaagaa
     4081 catgagttaa caatgttttt aatagattgt gagtatacat ttgataggaa taagttgatt
     4141 ttttacttta cagcagaagg aagaatagat tttagagaat tggtaaaaga cttagctgct
     4201 atatttaaaa ctagaataga acttagacaa ataggtgtca gagatgaagc taaatctata
     4261 ggaggtctag ggccttgtgg tagaaaactt tgttgttcat cttggttagg tgattttcaa
     4321 ccagtttcaa taaaaatggc aaaagaccaa agtctatctc taaatccaac aaaaatatct
     4381 ggaatatgtg ggagattatt ctgttgctta aaatatgagc atgatgtata tagtgaagca
     4441 atagaaaaaa tgcctgttgt aggtgcattg gtgcaatcag atgatggaaa aggaaaagtt
     4501 gtagaagtga atcctttatt agaacaaatt aaagtggaat ttcaagacaa gacagtaaag
     4561 atatacacaa gagaagatat aaaaatactt agagagccta aaaaatgtga tggctgtggt
     4621 ggtaaatgta aggataatga tggattagat gaagccacac taagagagct aaagaaatta
     4681 gaagattaaa tttaaggtag ggcttttcct acctttttta aagcaattaa tgcttaaagt
     4741 tattaatatt tgaggagaat ttatatatgc aattaaaaga ttcagaaaga atagatgatt
     4801 tacaattaaa aggccttaaa attatacaag atactaatgg tttttgtttt ggtatagatg
     4861 cagttttatt agccaatttt actaaaataa aaaaagatgc caaagtagta gatttgggta
     4921 ctggaactgg cattatacct attttgatag ctggaaaaag tgaagctaaa aaaattattg
     4981 gcgtggaaat acaagaagat gtatatgaaa tggcaactcg ttctataaaa ttaaatggat
     5041 tagaagaaag agttgagatt ataaatgaag atataaaata catagacaaa gtcttagaca
     5101 taaatggtta ccatgtagtc acatcaaatc ctccatatat gcatattgat ggaataaaaa
     5161 atccaaatga taaaaaagca atatcaagac atgaagtaag gtgcaatttg gaagatgtaa
     5221 ttagagctgc atccagactg gttatgccta gaggaaaatt cttcatgata catagaccaa
     5281 caagattggt tgatataata actttaggga gaaaatataa attagaacca aaggttattc
     5341 aatttgtgca tccaagacct caaaaagcac cgaacttagt tttgattcaa tttgtaaaag
     5401 atggaaggcc agagcttaaa atattggacc cattgtatgt ttatggagaa gatgggaatt
     5461 atacaaaaga attaaaagca atatataata ataaagatat aggagagttg taaatgagcg
     5521 ggaaattgta catatgtcca acaccaatag gaaacctaga agatataaca tatagaactt
     5581 taagaatatt aaaagaagta gacttgattg cagcagaaga tacaagacat agtataaaac
     5641 ttttaaatca ttttgaaatc tcaaaaccac taactagtta tcatgaacat aataaggatt
     5701 caaagggaga ttatttgata aataaactaa ttgatggtga aaatatagct ctgataagtg
     5761 atgcaggtat gcctggtata tctgacccag gagaagagat aataaaacaa gctatacaaa
     5821 ataacataga gatagaagta ttgccaggtg caacagcctt tgtaacggct ttagttggct
     5881 ctggtatgga cacacataga tttgtttttg agggcttttt agatagagat aaaaaagtta
     5941 ggaaagcaca attggaagaa ttaaaggaag aaagtagaac tataattttc tatgaatcac
     6001 cacatagatt gaaggataca ctaaaagata tgcttaaaat tcttggtaat aggaatattt
     6061 ctataaatag agaacttaca aaaaaatatc aagaaataat aagagaaaat atagaaacta
     6121 ccataaaaat atttgaggaa aaagaagtaa gaggagagtt tgtattaata gtagagggtt
     6181 ttcatggtga gaagtcaaag aaagaaaatt atgatgggct tacagatagg gaatatgttt
     6241 taaaactaat tgaaagtggt atgaacaaaa aagatgcaat aaaaatagtt tgtaaagata
     6301 gaaagttaaa gaaagatgtg gtttataaac aagttttaga tttataaaac ctgaatctga
     6361 ggtgatttta tggaaatagg aaaaattata atagagagtt taaagaggga agatacacat
     6421 aaaatattta tagaattaga taataagcat gaattagaaa aaataattcc taaaataagc
     6481 tgtatgaagt ctgtaggtga atgtaaatat catgtagtaa attgttttga acattctata
     6541 aatgcattaa aagaattaga aatagtatta aatgataggg atttttttcc aatacatcta
     6601 agaaaacatg tgtcaaacta tttaaaaaca tatattgaag aaggaataaa taagttaaat
     6661 gtattaaagc tgggaacatt tttacatgat ataggtaagc ctgacagtat gaccttagat
     6721 gaaaccggaa gagttcattt cacaaatcat gaaaaaatag gtgctcaaat aattgacaat
     6781 atgggaataa agttagagtt atcaacagag acatatagac ttataagtaa atatgtaaga
     6841 tatcatatga tacttttgtc tctatataag aaaaatgatt tgagtaggaa agaattaatt
     6901 aatgtattta acttagtaga tgaggatact ataggtgtaa taatgcttgg gtatgcagat
     6961 atagtgtcta cagtaaaatt attgggcaag agtggagaag tcagtgtgtt aaagacatat
     7021 atggaatata ttttaacaaa ttacttgtat aagagtaatt atacacatgt ataaatttag
     7081 ttaatataat tgaattttag atgattaatt gaagtttgaa atatacggat ttcaaaaaca
     7141 taaaagaagt tgtctttgtt gtaaaattat gaaagacaac tttttttata tcaaaaattg
     7201 aaattttatt aaggatactt aatggtctat taattaataa accattagta tttaatttat
     7261 attacaatat tgattttgct tgtattggcg ttgatagtat aacagaggtc ttagtagaac
     7321 caattttctt tatagtatca atcacatttt ctagctcgta catatctttt acaattactt
     7381 ttaaaagtaa gcaatcatca cctgttatat ggtgacattc tacaatccta gggtcctttg
     7441 cagctgactc aataaattct gtatatccat tgcttggaag agaaatatga ataaatgcct
     7501 ttataactct gcctaatgaa tctgggttga caatagcttt atatccttct ataacaccag
     7561 actcttctaa tcttttgact ctttctgaaa ctgcaggaga agttaaacca actatttttc
     7621 ctaagtcctt catagaaatt ctcccatcat cctgtaaaat ttctatgatt ctgtaatctg
     7681 taacatccat aaataaacag tcccccttaa ataaaaataa ttaatgctat aaaacttttt
     7741 tagaatctat catttgtgtt tttaaatacc aaagatttct agataaatca accttataaa
     7801 tgtgtggttt tgaaagtctt ttgtattgtt cccagatagt acttaattca tattgtacat
     7861 gattttttat ttcaagaaca gcttttttat tatatttgca tctgcctttt atatacaatg
     7921 gtttaagaag ctctttaact ttgtaatttg taaatacctt cgttttccat gtataagtag
     7981 gatggaagat ttctaaaggt ttagactcat ctataacttc atcatgtaac ataatcaaat
     8041 ctgcctctgc cttattgtct tcgttatata ttcttataac tttcttgtaa ccaggattat
     8101 ttattttttc tggattctca gaaatcttta tcttaggttc aagaactcct ttttcacaag
     8161 atgcagctaa tttataaact cctccaagag aaggtgaatc gaaagatgta atgagctttg
     8221 tacctactcc ccatgaattt atagtagctc cttctgcttt aagtgatgtt atggtatatt
     8281 cgtctaggtc attagatgca gtgatgctga tatctgaaaa gccagcatta tctaattgtt
     8341 ttttagcttc tttagataaa taagctaaat ctccagagtc aagtcttata cccataggtt
     8401 tgtatccttt ttcagaaata tttttgaata cttttattgc attaggaact ccactgttta
     8461 atacatcata agtatctaca agtagtaggc atttatctgg ataaacatca gcatatgctt
     8521 ggaatgcttc aagttcatta tcaaattttt gtacccaact gtgagcttgt gtaccaatta
     8581 taggtatatc aaacattttc cctgctagta cgtttgcagt tccagcacaa ccaccaacta
     8641 cggcagccct agccccatat atccctgcat ctggaccttg tgcacgacgt aatccaaatt
     8701 caaatacagg gtctccttga gctgcaaagc aaactctaga tgctttagta gcaataagag
     8761 actgaaaatt aactattgtt aacaatgctg tttcaataag ttgagcttga tataaaggtg
     8821 ccttaacagt aattaatggc tcattaggga acatgatagt tccttcctca acagcatata
     8881 tatctcctgt gaatttaaat tcttttaaaa attttaagaa cttgtcagaa aataaattta
     8941 agttttttaa gtactctaaa tcttcatctg aaaaatgaag attatctatg tattcaacaa
     9001 cctgatcaat accacaaact atagtatacc ctccatcaca agcgtttttt ctaaaaaaca
     9061 tatcaaatac aacaatgtct tcatgaatat tcttttcaaa atagccattt aacatagtaa
     9121 gctgatataa atcagtaaga agtgttagat ttctcattat ttctctcctt aattattatt
     9181 aaatattaaa aattgtaaaa actcccacac ttatactaaa acataatata gtacaacttt
     9241 caagtataaa gtattaccta actatcataa aattatttaa agaggaggat gattataata
     9301 ggaaaaatat ggttttatat ggtatcgata ggaataatag gaagcttgat ttctaaaaat
     9361 atgggtgaat taaataaagt tatattaagt gaaacatcaa aaggtataga gtttgcaata
     9421 agtctagctg gtatcatggc actctggatg gggataatga atatcgcaaa agaatcaggt
     9481 ttaattgaaa agataggtca aaaactaaat cctataatga aaagattatt tccttctatt
     9541 ccaaaaggtc ataaagcaat gtcttatata gttatgaata ttgctttaaa tatgttgggt
     9601 gctggaaatg gtgcaacagc atttggttta aaagcaatga gtgagcttca aactttgaat
     9661 aacaagaaag atacagccac taatgatatg attatgttta tggtaatcaa tatatcatct
     9721 atacaaataa ttccatttac tataatcaaa ttaaggatgg atatgggggc tcaaaatcca
     9781 agtgaaataa tttttacgac tttatttgca accataatat ctacagcagt agcaataata
     9841 acatgtaaat tttttcaaag aagatataga taaaggggat gtagatacat ggagatattt
     9901 tcaaacttac ttataccaat aataattctg tacatagtaa tttatggtaa atataaaaaa
     9961 atagatgtgt atgatagttt tgtaaaagga gcaattgatg gattaaaagc tgcatgggat
    10021 atcctaccat atataatagg tatatttttg gcaataggaa tattcaaaac tggtaaaggt
    10081 cttgatatgt tagaatggct atttacacca atagcaaata tgatgagtat accaaaagaa
    10141 ttaataggtc taataagtgt aaaaccttta tctggaagtg gtgctttagg gatgtacagt
    10201 gaacttgcaa atagagttgg aataggaagt ttagtagaaa aaatgggtgc tacgattgta
    10261 ggttcttctg agactatttt ttacacaatg gcaatatact atggaagtct gaagataaaa
    10321 aatactagac atacattatc atgtgctatg attagccatg ttgcaggtgt catagcagct
    10381 gtttttattt gctatgtaat atttgtataa tttgttgaca atatgggaaa aattttataa
    10441 tatagtgatt atatagaaac aaatagtaat acaaattaca agctatgaaa agaagagtaa
    10501 ataaaggttt tttctatcag agagctaggt taggtgaaag ctagtgtcaa aagctttatt
    10561 gaagatggtc ttggagcttt ttatctgagc aagtgtgcta gggtaaaacg gttggacacg
    10621 ttatagtcta ctaaggtatc tataaaatgt ttctacattt catgtgaaac ataactatta
    10681 tagatgaatt agggtggtac cgtgaataat ctcgccccta tgttaactca taggaggcga
    10741 ttttttatta tttaaatgaa agaatcatat gattacgaac gataaaaaat taggaggtaa
    10801 ataacatgag caaaccgagt ttttatgtaa caacaccaat atactatcca agtggaggat
    10861 tacacatagg acatacttat tcaacagtag ctgcagatac aatagctaga ttcaagcgtt
    10921 tctgtggata tgatgtaaag ttcttaacag gaacagatga gcatggtgaa aaaattcaaa
    10981 agaaagccat agaacaagga atgtcagaga tagagtatct tgatggaatg ataaaagata
    11041 taaaggcctt atggaatact atggatatat cttatgatga ttttataaga actacagaaa
    11101 aaagacatac agacataata caaaagatat ttactaaact atatgagcaa ggtgatatat
    11161 ataaaggtga atatgaaggt agatactgta ctccttgtga gagtttctgg acagaatctc
    11221 aattactaga aggaaataaa tgccctgact gtggaagaga aacatattta gtaaaagaag
    11281 aatcttattt ctttagatta tctaaatatg aagacagatt aaaagagtta tttaaagatg
    11341 atagtttctg ttttcctgct gctagaaaaa atgaaatggt ggcaaacttt ttagacaaag
    11401 gattagaaga tttaagcgta actagaacga cttttgactg gggtataaaa gttccttttg
    11461 atgaaaaaca tgtaatttat gtgtgggtag atgctttatg taactatata acagcattag
    11521 gttatatgac tgataatgat gaagaattta aaaaatattg gcctgccaat gttcaaatag
    11581 taggtaaaga aatagtgaga ttccatacaa taatatggcc agcgctttta atggctttag
    11641 gtctagaagt tccaaaacaa gtatttggac atggatggat actatttgct gatgataaaa
    11701 tgagtaaatc aaagggtaat gtggtttatc cagaacctat aatagaaaga tatggaatag
    11761 acacacttaa gtacttctta ttaagagagt ttgcatttgg gcaagatgga agttatactc
    11821 atagaaattt tgtaacaaga ataaattatg atttagcaaa tgatttagga aacttaataa
    11881 gtagaactgt agctatggtt gaaaaataca ataatggtat aataccaaca gcaaaagttt
    11941 caactgattt tgatgctgac ttaaaagaac aagctgtttc aactagagaa aactttgaag
    12001 ctgaaatgga taaaatgcaa ttccatgaag cattagagag tgtatggaaa ttagttagaa
    12061 gaactaacaa atatatagat gaaactatgc cttgggcact agctaaagat gaaacgaaga
    12121 aaggtgaatt agacacagtt ttatataatt tatgtgaatc tataagaata atcgcaacac
    12181 taataaatcc tataatgaat gagactgcta ataaaatata tgaacatata ggaataaaag
    12241 gtcaagatga tataactaca tgggaaagta caaaaacatt tggtcttatt ggagaaaatg
    12301 taaaagtatt taaaggtgaa cctttattcc caagattaga tgtagaaaaa gagatagaag
    12361 aattaactaa aatgttctct gggaaacctc cagtagaaga aaaaccttta gagcataaag
    12421 aagaaattac tattgatgat ttagacaaaa tagagcttag agtagggaaa ataataagct
    12481 gtgaaaaaca tccaaaagca aataaattat tagtatcaca agttaagatt ggaccagaaa
    12541 caagacaaat agtatcagga atagctgaat actataagcc agaggattta gtaggaaaag
    12601 aggttacagt ggtatgtaac ttaaaaccag ttaaattaag aggtgtagaa tctcaaggta
    12661 tgatattagc agcaggcgat gatggagacc catatgtttt accatttaca caaggggcta
    12721 aagatggatg cgaggttcgt tagtaggtaa ttaaatagta aggagattaa agatgttatt
    12781 tgactcacat gcacatttaa atgatgaaag ttttgatgaa gatagagatg aacttattgg
    12841 ttcattaaaa gataaaggtg tagatttggt tgtaaatcca ggagcagata tagagacgtc
    12901 gataacagca attgaacttg cgaaaaaata cgactttata tattcagcag ttggggtaca
    12961 tccacatgat gtatcaaaac tagatgatac agcaatagaa actctaagaa aacttgcaac
    13021 tgagaatgaa aaagttgtag ctattggaga gattggatta gattattatt atgattattc
    13081 tccaagagaa gaacaaaaag agtggtttaa gaagcaaatt gaattagcta atgagctaaa
    13141 acttccaata ataatacatg atagagatgc acatggagat acttttgaga taataaagaa
    13201 tactaaaaat cctgaaatag gatgtgtact tcattgttat agtgggaatg tagagttagc
    13261 tagagaatat gttaagatgg gttgttatat atcaattcca ggcacggtta cttttaagaa
    13321 taataaaaaa actagagaag tagtaagaga aatacctcta gaaagattat tcatagagac
    13381 tgattcacca tatatgtcac cagagccaca tagaggaaag agaaacaatc cttcccaagt
    13441 atcttttgtt gctgataaga tagcccagga aaaagggata tcttatgaag aagtatgtag
    13501 agttacaaaa gaaaatgcaa agaaattttt taatataaaa tagacaaatt aaatcttata
    13561 atgatatata taataagtca ttataagtat aggatgagag tgcctcaaaa tgagtttttt
    13621 agttcatgag gcactctttt ttttatgaaa tcaaatatat tttcatcatt tcaacaatga
    13681 aaaagaagtt tatcatattt tgagatagtt tgtttttatt tatttaattc atattttaaa
    13741 atatattttc ttaacattgt taaaaaagaa tttacaagat attcattaga attaactcaa
    13801 ctctaatatt cacttaactt aagttgttta ttatattatt aaagagaagt aaacgaaagg
    13861 tagattaagg aggttgaatt ttgtatacag ttgatagtac taagatattg ataaatatga
    13921 acttagagaa actagaaaag atatactcaa tgataaaaga tacatcaagt atttctataa
    13981 ttaaagaacc taacttggct acagtaatgg taagagctaa tgaaagtgta aaaaacacaa
    14041 catttaattt aggagagata ttagttactg aatgtagtgt aaaggtagat gaaagcttgg
    14101 gttacggaat agtttcagaa aacaataata agaaagccat ttatttagca gttatagatg
    14161 cagttttaca tagcaataac agtaaatttg atgagttaaa gaattacata aataaaagtg
    14221 tatatgaaga gaacttaagg tatgaacaag agattattga tgaatttagc ttgattaata
    14281 aaacgaaagt tcaattcaat gctatggatt aaataggagg agaatcatgg taaattatac
    14341 acaagaaata tatagaaaga tgctagatag tgcttcattt cctgggaaat taaataatat
    14401 agataatata aatatagaaa ataatacaaa actattgaat ggagcaattg gtatagcaat
    14461 cactttatta gaccaagaag ttaccttcta tatagaaaat tatactcaaa aagatataaa
    14521 aaatataaga gcgcttacaa tgtcaaatca aatagattat agaaaatcag attatatatt
    14581 tttagatatt aattcagaag tggatatatt acagattaaa ataggttctt ttgaatatcc
    14641 tgatgaaagt gcaactatag tacatcaagt aaatgattta tcaacgtact ctcaaactaa
    14701 gtatataaag cttgatttga gtggtcctgg tataaaatct aaaaatagta tatatataaa
    14761 tggaattaga gaagaattta tagaaagatt atctaccata aataaagatt atccaatagg
    14821 aatagatttg attttagtag ataaaaaagg agaaattgca tttataccaa ggtcatcaaa
    14881 attaagttgg gaggtattgt agaaatggct tatgtagcag ttaaaggtgg agaagaagcc
    14941 atattacagg ctaaaaatat acttgagttt tatagggtaa aaggagatag cttgcctata
    15001 gatgtaaagc agattgagga acaaatgtct tatgctgtag acaaagtaat gtctgaagga
    15061 agtttataca acaaggaact atcagcattg gctataaaac aagctcaagg tgatatatta
    15121 gaagcctctt tctatgtaag agctttaagg tcaacaatgc ctagaattac atattcagaa
    15181 cccataaata cagaagaaat gagaataaaa agaagaatat cagctacttt taaagatata
    15241 ccaggaggtc agtatcttgg ggcaactaga gactatgaaa atagaatatt gaatgtagaa
    15301 ttattagaag aagatgaaaa aaagaataga gattttagag atagttttat aagtgaatta
    15361 gaaacagtag atgaaatccc tgaatttaca aaaatatcta atatatttag aaaagaaaat
    15421 ttattacaag aagaagtttg tgaaaacaaa ttggaagaag ttattgatga tattacaaga
    15481 aatagtttaa gatttccagt ttctaggtca gcaaagttac aggcattaac tagaggtgaa
    15541 agtggagtag tgtcaggttt tgcttatgct attgtaagag gttttggtga tgaacatcca
    15601 tatataagtg aacttagaac tggtaatgta tttataaaag taaaacatcc catctatgaa
    15661 gatgaagaaa taataatagg tgatatgctg gttactgaat gtgaaatagt ttcaaaagca
    15721 tcacaaaata agactgaaaa ttctaaaact aattcggaag ataaaaataa gatgtcttta
    15781 ggatatggtc tttgtatggg gaataatgag aataaggcta tatctatggc catactagac
    15841 aaatctttgg agccaaatag tgaaaaacta gcacaagatg aagaatttgt attgcttcat
    15901 atagatggaa tagattcatt aggatttata tctcacttta agcttcctca ctatgtagat
    15961 tttaaagcgg atgtagaaag aataaaatag tttgtggagg taagtttagg tgatatataa
    16021 ctatggtttt ttagacgaaa acacaaaaaa agaaataaga agaaagatat taaaagcaat
    16081 atcaatacct ggttatcaag ttccctttgg ttcaagagag ttgcctatag ctaagggatg
    16141 gggtactgga ggtttacaat taacactatc attaattggt aaaaatgatg tagtaaaagt
    16201 aattgaccaa ggaagtgatg attctacaaa tgcttgtaat ataaggagct ttattgcaag
    16261 tgtaagtaat gtagaaacca caaaagatac attagaagct acattgattc aaacgagaca
    16321 tagaatacca gaagaaaaac ttaaatctaa tcaaatacta atatttcaag tgccaatacc
    16381 agaaaccctt agaatagtag aacctagtga agtagaaaca agaagaatgc attcagaaga
    16441 agattatagt aggatgtggg tatatcttta tgaagatata gttagattta atgatatatc
    16501 tatagcagtt gaatatccat gtaaagtaaa tgatagatat ttaatgaatc catcacctat
    16561 acctagattt gatataaaaa aattaaatat gtcagacaat ttattcttgt ttggtgcagg
    16621 tagagaaaaa agaatttatg ctattcctcc atatacaaag gtagaacctt tagagtttga
    16681 ggattataag tttgaagagg aaaagtttga aggaaaatac tgtagtttat gtaacagtac
    16741 aaatacattt ttagatgaag tatatgacag tgacactaat gaaaagtact atagttgctc
    16801 agatacaagt tattgtgaaa aagttagatt aaaaaataac agtatagatg tgacaatagg
    16861 aggtacttgg aatgagtaaa ataaatgact ctaaaagatt agaaaatata gacaagcaag
    16921 tattaatagg aagaaatatc aatcttattt atggagatgg gtgtgaaaag tgttttgaaa
    16981 gcacaggata tgaaagcaat aatatatgta agtattgtgg ttctatagtt gcatgtaata
    17041 atgtaaattt agaactttat gaaggagaag tccttggaat tgtaggtgaa tctggttcag
    17101 gaaaaagcac tttattaaaa atactgtttt tccaagaaca tgcaaatagt ggagaagtat
    17161 atatatccca ttacaataaa gacacaaata tactagagct ttcagaccaa aaaaagagat
    17221 acataaagaa tcattttatg ggtattgtgt atcaaaatcc ccaccttggt ttaaatttag
    17281 actttagtag tggtggtaat atagcagaaa aattattgat ggcaaattta tataatgttg
    17341 aaaaaataag agatagaggc aaagaacttt taataaaaac taatatacct gtagaaagaa
    17401 tagaccataa accaaaatac tttagtgggg gaatgcaaca acgagttcaa atagcaaaag
    17461 ctctttcaaa taaccctcca atattgctat tagatgaggt tacaacaggt ttagatgttt
    17521 ctgtgcaagc ggaagtattg gatttaataa gagaaatcca aagagaactt aagatttcta
    17581 tgatagttgt atcccatgac tttgatgtta taaagatgct tgctgatagg acaattgtaa
    17641 tgaaaaatgg aagtgtaatt gagtctggtc ttacagacca aataatggag gacccacaac
    17701 acccatatac tcagcaactt ataaattcat tgctataaat atcgtttgta aataagcaaa
    17761 atgggggttt ttaataaaat gaaagaaact atacttgaag taaataattt tagtaaagac
    17821 tttgagttac atgcattgaa caagactata acggcatgta gtaatataag ttttgaagtt
    17881 tcaaaaggtg agtttttagg aataataggt aaatctggag caggtaagtc taccatatta
    17941 aaaagtatct ataaaacata tataccaaca actggagaaa taatttttaa ttcagaaata
    18001 tatggtaatg tagacctggc taaaattgga gaccgagaaa tgataaatct tagaaagaaa
    18061 gaaataggat atgtatcaca gtttttaaag acacttccac gaataactgc aattgaactg
    18121 gtagtacatt ctttaattga gagtgggttt gaaaaagatt gttcgtatga tatggcaaaa
    18181 gatatactta accaatttga aataaaggaa aatttatggg atgcgtatcc aaataatttt
    18241 tctggtggag aaaaattaag attaaattta gctcaagcta tggttaaaaa gcctagactt
    18301 ttgttacttg atgaaccaac tgcatcactt gataatcaat ctaaaatata tgtaaaagaa
    18361 aaaatgttgg agcttaaaag tcaaggaact acaatgatag gaatttttca tgatatagag
    18421 tttatggaaa ctgttataga taagaccttt actatgacaa aagggactat aagtgaaagt
    18481 ggggtagcct agatgataaa actaattcat aatgcaaata ttgtattaga agatatgatt
    18541 ttagaaaatg gtcatttaat catagaggga gatacaataa aaaaagtatc aaatgataag
    18601 attgattacg catttgactt taatgagata gatgaaataa tagatgcaaa aaacttatat
    18661 gtaatacctg gtattataga tattcacagt gatgccattg aaaaggaaat agagccgaga
    18721 ccaagtacat tattaccatt taatatggca ttttatgaac tagataaaaa actacctgca
    18781 aatggaataa ctacagttta tcattctata tctttagggg atggagtagg agttagaagt
    18841 attgataact ctttaaagat gattaaaaat attgattcat ataaaaatat agatagtaag
    18901 agcataaatc ataaagttca tttaagatat gaagtgttgt attatgaagg tttagaaaag
    18961 gttttagaac tattagatga aaataaaata gactacttat caataatgga ccattctcca
    19021 ggacaaggtc agtatacaaa tccaacattt tataaagagt atgctactaa agtgtgggga
    19081 gttacagaaa attatgtaga tacatggtta gatgatttag taaatctgca tgataattta
    19141 gattggaata aaatagctaa tattataggt atagccaaaa ctaaaaatat aaatgttgca
    19201 tcacatgatg atgatacatt agaaaaaatg gatttcataa aaaatatagg cataaatgta
    19261 tctgaatttc ctataactct tgaagttgca aaacattcaa agaaattggg tgttctaact
    19321 tgtttaggtg caccgaatat tgtaagaggt aaatctcata ataacaattt aaaagcaatg
    19381 gatgctatat tggaagattg ttgtgacatt gtgtgttcgg attatcttcc atcagctatg
    19441 ataaagtcta tgtgtatagt tgcagaaaga ataaataatt taaataaagc agtcagttta
    19501 tttacctcaa atcctgctaa agcagttggt atatatgatg aaagaggtag tataaaagaa
    19561 aataaaaaag cagatttagt tttagtagat attgatagtg aatatccaaa ggttgtaaat
    19621 actattgtaa atggaaaaac agtttataaa agggaggtat aaagattgct aacagagtta
    19681 cattgtcata caagtatatc agataataat tttactactg aagaaataat aaaaaaagca
    19741 gcagaaaaga atataaatat cttagcaata acaaatcatg acacattatc tggattggat
    19801 gaagctcttg tgcttggaga gcattatgga ataacaataa taccaggtat agaaatttca
    19861 gcctatgatt ataaaaatag aaaaagagtt catattcttg gatataacat agatttaaac
    19921 agtcaagaaa taaaaaattt gtgcaatcca atggtatgtg acagacataa agcatctgtt
    19981 aagatggtaa ataaaattat agatttagga tacaaaatat ctctggaaga tgtaaagaaa
    20041 tattcatcaa agactggaat atttaaacaa catataatga aagctcttat agataaagga
    20101 tatacagata atatatattc aaatctatat aaagaattgt ttcatagagg aaacggcaag
    20161 gtatatgtat ctttaaaata tgtggattac agagatgcaa taaaagctat aaaaaattct
    20221 ggtggaattt gtgtgttagc tcacccgggt caaatggata attttagcgc tattgaagag
    20281 atggtaaaag taggattaga tggaatagaa gtatatcatc catctcacaa caaagaacta
    20341 gaaaaagagt cgctttctta tgctaagaag tataatctag tggtcacagg aggttcagat
    20401 taccacggat tttattctca acataattat gaacttggaa gcaagagctt aaataaagaa
    20461 gatttattta agtttaggtt agctttagga ggggtattat aaatgtcttt tttacaagta
    20521 aaaaatgtag gtaaaagtta tggacaagtt aaggtgttaa aagacatatc tattgatatt
    20581 gaaaaaggag agtttatttg tttactaggt ccaagtggtt gtggaaaaag tacactactt
    20641 agaataattg cagggcttga ggataaacat ggtggaaaaa taataataaa tgataaggat
    20701 atgactaatt caccacctga aagtagaaat tttggtatag tttttcaatc atatgcatta
    20761 tttccaaata tgaatgttta caaaaacata gcctttggac tagaaaataa aaacataagt
    20821 aaatctaata ttgataaaaa agttaaagaa gttctagaag ttgtagaatt aagtggatat
    20881 gagaaaaaat atccatcaca attatcaggt ggacaacaac aaagggttgc attagctcgt
    20941 gcgattgctt tagagccaga ctttttactt cttgatgaac ctttatctgc attagatgca
    21001 aaagtaagac ttaaacttag ggagcagatt agaagtttac atagaaaact aggcattaca
    21061 actataatgg taacgcatga ccaagaagaa gctctttgtt tagctgataa gatggttgtt
    21121 atgaatagag gagaaataat acaagttgga acgccaaagg aggtatataa aaatccagaa
    21181 acaccttttg tagctgattt tataggaaca ataaatttta tagatgatgg tattaataag
    21241 atagctatta gaccagaaga tataaaagta gagtctaata gagattctaa agataaggat
    21301 ataaaagtgg gagaaatttt agatatcgaa tttagaggat ttaactatag aattacagtt
    21361 gagtatcgtt ctaagcaaat gaaattagat gtagtttcca aagttgcaga acaaatgaaa
    21421 ctgtgcatag gttctaaaat aaactttaag atacctaaag aaggaattgt acaatataaa
    21481 tcagagggat gtgcttaata gctaggggtg aataaatgat aacatcaaaa aataaaagaa
    21541 gaataagtga tagcacaata caaaaatatt tcttgatttt ttcggtaatt gtactaatag
    21601 tatttatatt atttccatta gtatcattat taaaaaatgc atttatggat acaagtggaa
    21661 attttatagg aatttcaaac tttagtaaat atgttgaaaa tccaagtctt atagcatcat
    21721 ttaaaaattc aatttttgta tctacagtct catctttaat atcactatgt ttagcattta
    21781 tatattcata cgcaataaca agaacaaaca taaagtttaa agattttttt aaaactatgg
    21841 gaatgtttcc actttttgca ccaactatgt tatatggtat ttcacttata tacctttttg
    21901 gaaataaggg aatctttaca accatgggtc tggaagtacc actgtatggt ccattaggaa
    21961 taattatttc tcagattcta tttacatttc cacaagcttt tttaatatta tctgtagcac
    22021 tttcgatggc tgattacaga ctttatgaag cagcagatag cttgggtgct agtgaattta
    22081 agaaattttg caaaataaca attcctggta taaagtactc attacttagt tcattctttg
    22141 tatcctttat acttgcattt acagattttg gagcagctaa ggtagtcgga ggaaactaca
    22201 atgtactggc tactgacata tataaacaag tagttggaca atttaacata ccaatgggag
    22261 ctactgtttc tatggtaatg ttaattcctg tactaatagc atttacatta gataagatgg
    22321 caagtaagaa acaaggtatg accataactg caaagtctat gccatataag attaaggaaa
    22381 ataagtttag agatagagta tttttaatag tatgtagttt tataacattg ctaattttta
    22441 ttttaatatt cgtttcagtt ataggttcag ttataaagtt atggccatat aatttaagct
    22501 ttacaatgga acactataca tttaaaggta ttttgggaag tggaataaaa acatacttaa
    22561 gcagtttgaa aatatcaact ttaacagcaa tatttggaac tatatttgta ttttttagtg
    22621 cttatatgat agaaaaggtg gataagtttc ctaaattaag acaaacagct taccttttat
    22681 caatgatacc aatggcctta cctggcttag ttttaggtat atcatatata acttttttta
    22741 actcagcaag taatccatta aattttttat atggaagtac agcaatatta gttatagtaa
    22801 atgtagttca tttttattca gtttgtttta taacctcaaa ttcatcttta aaaatgttgg
    22861 ataaagagta tgaattagtt gcaaaatcca taaatattcc attttataaa gtatttttta
    22921 atataacagt tccaatgtct ataacatcaa tacttgaaat agtagtatat tattttgtaa
    22981 attcaatggt tactgtttca gcattaatat ttttatatac acctcaaact cagactgcat
    23041 caatatcaat actaaagtta gatgagatag gatatatagg accatcagct gctatggcag
    23101 tattagtgct tttaacaaat ataatagtaa gacttttgta cgaatttgta acaaagaaat
    23161 taaaaaataa cacacaaaaa tggcagcaaa aagatgttgc ataggggagg taaaaatgaa
    23221 atttaagaag ctagtttctt taggagtatt atcaacactt ttattaagtg taataacagg
    23281 atgtagtact gattcatcag gttcagattc aaagtctgat agtaagacaa aaggggattt
    23341 aacagtttac acagcaattg aagaagatag tatagagcca tatttagcta catttaaaga
    23401 gaaatatcca gatattaaat taaatattgt tagggcatca acaggagata taacagcaag
    23461 attattagca gaaaaggata atcctcaagc agatgttgta tggggagttg cagccacaag
    23521 cttattggtt gcagatgacc aggggatgtt agaaccatat gctccaaaag gttctgaaga
    23581 aatagagtct gcatttaaag atgataaaga agttccttct tgggttggga tagatgcttg
    23641 gatgacaggt ataacagtaa acactaaaga attaagtgat aagaacatcc cagttcctag
    23701 ttcttacgaa gatttaataa agccagaata taaaggtctt atatctatgc ctaatccatc
    23761 ttcttctggt acagggtact taacagtatc agcccttata caaattatgg gggaagaaaa
    23821 agcatggcag tatatggata agttacatga gaatattggt gtatacactc aatctggttc
    23881 agctccagct acatcagcag cttcaggaga atatcctatt ggtatatctt ttggatatag
    23941 aggtataaag ttaaaagagg aaggctatcc agtagaagta gtatttccaa aagaaggttc
    24001 tggatgggat atagaagcaa atgcacttgt gaaaaaagat aatataaaag aagcatcaaa
    24061 agtattttta gattgggcta taagtaaaga tgcaatgaac gaatactcta agaactatgc
    24121 agttactact atttctacag gaaatccaat accagaagga ttccctaaaa agccattaga
    24181 gcaaatgata gataatgatt taaaatcagc agcaaaaaat agagaagata tactaaataa
    24241 atggatatca aaatatgatg gtaagacaga aaaagagagt taagtaaaac tatacaaatg
    24301 gagtaaaaag aaagaatttt tttaagtaga ttttattata ataatataag ttgagaataa
    24361 tataggtcaa gaaaagtgaa tattctataa aaatgtatag agtaagtata ccattcagtt
    24421 tgaatggtat attttttatt tttagagatt aatttagaaa tagatatact acagtttaaa
    24481 atagtatatt ttaatttcat tattaaagta tagatattat atataaagta aataaattat
    24541 tgagcgatta ttaataagat atgtataaat tttaatttgg gaacttgtgt tatatatcat
    24601 gaaaaaagag aaaaaataaa aggtaaattg tttcttgata acttgaaatt ggaagtgaga
    24661 atatttaact agagaagaat tatttaagtt taagtcagct ttaggaggag gaattataaa
    24721 tgtctttttt acaagtaaaa aatgtaggta aaagttatgg acaagttaag gtgctaaaag
    24781 acatatctat tgatattgaa aaaggggagt ttatttgctt attaggtcca agtggttgtg
    24841 gtaaaagtac attgcttaga ataattgcag gacttgagga taaacatgat ggaaaaataa
    24901 taataaatga taaggatatg actaactcac cacctgaaag tagaaacttt ggtattgttt
    24961 tccaatcata tgcactattt ccaaatatga atgtatataa aaatatagcc tttggattag
    25021 aaaataaaaa tataagtaaa tctgatatag ataagaaggt tagagatatt ttagaagttg
    25081 tagaattaag tggatatgat aaaaaatatc catcacaatt atcaggtgga caacaacaaa
    25141 gggttgcact agctcgtgcg attgctttag agccagactt tttgcttctt gatgaacctt
    25201 tatctgcatt agatgcaaaa gtaagactta aacttaggga acagattaaa agtttacata
    25261 gaaaactagg catcacaact ataatggtaa cacatgacca agaggaagct ctttgtttag
    25321 ctgataaaat ggttgttatg aataatggag aggtaataca gattggaact cctaaagaag
    25381 tctataaaag tccaaaaaca ccttttgtag ctgattttat aggaacaata aattttatag
    25441 atgatgatgt gaatatgata gcaattagac cagaagatat aaaggtagaa tttaatagag
    25501 actttaaaga aattgatgta aaagtaggag agattttgga tatagaattt agaggattca
    25561 actatagaat tacagttgaa tattgttcta agcaaataaa gttggacgta gtttcaaagg
    25621 tagtggaaca aatgaaacta tgtgtaggtt ctaaaataaa cttcaagata cctaaagaaa
    25681 gaaccataca atataaatca gagggatgtg cttaatagct agaggtggat aaatgataac
    25741 aataaaaaat aaaagaagaa taagtgatag taagatacaa aaatgttttt tagttttttt
    25801 agtgattgca ttagtagtat ttatattatt tccattaata tcactattaa aaaatgcatt
    25861 tatggataca agtggaagtt ttgtaggaat ttcaaacttt agtaaatata ttgaaaatcc
    25921 cactcttata gcatcattta aaaactcaat ttttgtatct acaatttcat ccttaatatc
    25981 actatgttta gcgtttatat attcatatgc aataacaaga acgaatataa ggtttaaaaa
    26041 cttttttaaa actatgggca tatttccgct tttcgcacca gctatgctat atggtatttc
    26101 acttatatac ctttttggaa acaagggaat ctttacaatt ataggcatag aagtaccact
    26161 atatggtcca ttaggaataa ttatttgtca aatactgttt acatttccac aggccttttt
    26221 aatattatct gtagcacttt cgatggctga ttatagactt tatgaagcag cagatagctt
    26281 aggggctagt gaatttaaga agttcttcaa aataacaatt cctggtataa agtattcatt
    26341 agttagttcg ttctttgtat cttttatact tgcatttaca gattttggag cagcaaagat
    26401 agttggagga aactacaatg tattggctac tgacatatat aaacaagtgg taggtcaatt
    26461 taacatacca atgggagcta ctgtctctat ggtaatgtta attcctgtac taatagcatt
    26521 tacagtagat aagatagcaa gtaaaaagca agggatgact ataactgcaa agtctatgcc
    26581 atataagatt aaggaaaata agtttagaga tagagtattt ttaatagcat gtagttttat
    26641 aactttatta atctttattt tgatatttgt ttcagttata ggctcagtta taaaattatg
    26701 gccatatgat ttaagcttta caatggaaca ctatacgttt aaaggtatat caggaaatgg
    26761 aatcaaaaca tatttaagca gtttaaaaat atcaatttta acagcaatat ttggaactat
    26821 atttgtattt tttagtgctt atatgataga aaaagtggat aagtttccta gactgagaca
    26881 aatatcttat tttttatcaa tgataccaat ggcattacct ggtttggctt taggtatatc
    26941 gtatataacc tttttcaatt cagcaagtaa tccattaaat tttttatatg gaagtacaac
    27001 aataatggtt atagccaata tagttcattt ttattcagtt tgctttataa cttcaaattc
    27061 atctttaaaa atgttggata gagagtatga attagttgca aaatctataa atattccatt
    27121 ttataaggtg tttttttatg taacacttcc aatgtccata acatcaatac ttgaagtggc
    27181 tgtatattac ttcgtaaatt caatggttac tgtttcagca ttaatatttt tatatatacc
    27241 tcaaactcaa actgcatcaa tatcgatact aaagttagaa gagatagggt atatagggcc
    27301 atcagctgct atggcagtat tagtgttttt aacaaatata atagtaaaac ttttgtatga
    27361 attgacaaca aagaaattaa aaactaagac acaaaaatgg caacaaaaag aagttgcata
    27421 gaggaggtaa aaatgaaatt taggaaatta gtctctttag gaatattatc aacactttta
    27481 ttgagtgtaa taactggatg taataatgct tcatcaggtt caaatttaaa gtctaataat
    27541 aagataaaag gagagttaac agtttataca gcaattgaag aagatagtat agatacatat
    27601 ttaactacat ttaaagagaa atatccagat attaaattga atgtacttag attatcagta
    27661 ggagatataa cagcaagatt attagcagaa aaagataatc ctaaagcaga tgtgttatgg
    27721 ggggttgcag ctacaagttt gataatttta gatgacaaag aaatgctaga gccatacgct
    27781 ccgaaaggct ttgataaggt aaatcctgta tttaaagatg ataagaaagt tccttcttgg
    27841 gttggaatag atgcttggat gactggtata acagtaaata ctaaagaatt aagtgataag
    27901 aacataccag ttcctagttc ttatgaagat ttaataaagc cagaatataa aggtcttata
    27961 tctatgccta atccagcttc ttctggaaca ggatatttaa cagtatcaga acttatacaa
    28021 attatgggtg aagaaaaagc atggcagtat atggataaat tgcataaaaa tattggtgta
    28081 tacactcagt ctggttcagc gccagctata ttagcagctt caggagaata tcccattggt
    28141 atatcttttg gaaatagagg tataaagtta aaaggtgaag gttatccagt agaagtagta
    28201 tttccaaaag aaggttctgg atgggagata gaatcaaatg cacttgtgaa aaaagataat
    28261 ataaaagaag catcaaaagt atttttagat tgggctataa gtaaagatgc aatgaatgag
    28321 tattctaaga attttgcagt tactacaatt gacacgggaa atccggtgcc agaaggattt
    28381 ccaaagaatc cattagaaca gatgatagat aatgatttaa aatcagcagc aagaaataga
    28441 gaggctatac taaataaatg gatagaaaaa tatgatggaa agacagaaaa agagagctaa
    28501 gccttgcaat aaaatttagt acaaaaagcg cctagaatat aagttttata tctaggctct
    28561 tttgatatat ttatttaaaa tgcatatttc tatataaaaa taaatagttt agtaccttga
    28621 ttaaattaaa taaaaacctt aaaataaaga gatgtaaaga aaaactaaaa acgaataaaa
    28681 ggtgaattta tatgataaaa gaaataatag tagtagaggg tagagatgac gttacagcag
    28741 ttaagagagc aatagatgca gaacttataa ctacaggtgg atttggattt ccaaaaggtg
    28801 taatggagcg tataaaagct gctaatgaaa gacgtggtgt tataatattt acagacccag
    28861 attttgcagg tgaaaaaata agaaaaaaaa tagcatcaga agttccagga tgtaaacatg
    28921 catttctacc gagagaggaa gctaaaaagg atggagatat aggtattgag aatgctactc
    28981 ctcaaagtat aatagcagct ctgaataaag ttagaactga aaatacagaa aaaagagatg
    29041 aatttaagca agttgactta attagaaatg gtcttatagg taatgaagaa gcatcactta
    29101 gaagagatgc acttggaaaa atacttggaa ttggatatgg aaatgcaaaa caatttttaa
    29161 atagattgaa taattatgga gttgaaagag aagaatttat agatgcatta aaacaaatct
    29221 aaatgtaatg tttaatgtat gaaaaatatg tatataaaat aaattgtgga attacggtta
    29281 atttaagata aattatttat aatatatacc ttattttaaa tcaatgtaaa tacatataaa
    29341 taagtataat taataaaatt aaatatcaaa ataagttaaa aaggagtaaa taatggatag
    29401 actatcttca cataatgcaa caaaggaagt agtacaaaaa tataatttta aattttcaaa
    29461 gtctttaggt caaaatttct tgatagatag taatataatt gataaaatct tatctggagc
    29521 tagaatcaca agaggagata atatcataga aataggacct ggtataggaa ctcttactcg
    29581 tgagatgggt aaaatagcag aaaaagtagt ggctatagaa atcgatagaa atttaattcc
    29641 tatattgaaa gataccttgt cagatttaga taatacagag gttgtaaatc aagatatact
    29701 aaaagtagac atacaggaat tagtaaaaga taaattaaat ggtgggccag ttaagcttgt
    29761 agcaaatctt ccatattata taactactcc aatagttatg aaatttttag aggaagacat
    29821 acctgtaaca gacatagtag tcatggttca aaaagaagtt gcagatagaa tgaatgctat
    29881 tccgggtact aaagattatg gggcattatc tatagctgtt caatactatt gtgatacaga
    29941 gattgtggca aaagctccaa gacatatgtt tataccacaa ccaaatgtag attccacagt
    30001 tataggttta catgtaagag ataaaagaaa atatgatgtt cataatgaag acatattttt
    30061 taaaacagta aaagcatcct ttggacaaag aagaaaaact cttcttaatt cgttgggagg
    30121 tcttggtttt cttaataaag atgaaataag agaaatatta aaagaagcta atatagacga
    30181 aaaaagaagg ggtgaaactc ttagtataga agagttttca gttctttcaa atataataaa
    30241 tacaaaagta tcttctaaat agaaggtact ttttttaatt ttgttaacat atattgttta
    30301 gagaaactgt gttaaggggg gattgcagtg ggttctaaaa gaaagtttaa aagagactat
    30361 ataatactag aagctaaaga tataaacttt agatacaaag aacgagtact gccaaaagct
    30421 tttgcaaaag ttgaagtaaa tgatgaaaaa gcaattattg cattatatgt agaaaatcta
    30481 aaatatgtta aagatgggta taaagcagta gcaataaaag atgaccatgg attaatagac
    30541 ttaggaaata taattttaaa tgaacaagga agaggtgaat ttgttttaga tttagaagat
    30601 tatgatgatg agataaaagg tattgcatta ttgtatgaaa gaaatatacc tttaattgga
    30661 tttaagggaa ataagcttga aaattatgag gacatattat ttcaagaggt agaggaagaa
    30721 gaatatgaag aatatgaaga gttggaagaa gaagacgaag agatagagga taatgaggaa
    30781 agtgatagag acgaagatag tgaagaagaa tatattatag aagaatatga tgaagatgag
    30841 tatgaagact attgggaaga tgatgaagat agtgaagaag gagagttaaa agcaagaacg
    30901 gaagtagaag attctggtga tgaggaaata gaagagttca ataattataa ggaaatagaa
    30961 aattataata gggttaaagt acaggaagaa tatatagaca tagaatatga tgaggaagaa
    31021 gaggaagaag aagtttttga agtaaataga gaagaagata ggtttgtttc ctcaaaacct
    31081 actaaatcaa agaaagttca aaaagatcag aataatattg aaaaaataaa aagagctaat
    31141 ggagtaagtc aaggagagag tggaaataaa caaaccagta cattacttat gccaagacaa
    31201 ataaaaaaag gtttgaaatt atttaaagaa gtaaaacctt ttgtaacaga ttatatagat
    31261 aagacaagat ggtggaaaat agagataaat cctacaacac tgtgtggata tacaatgcct
    31321 tatttaggat atttaaacgt attgaattac actatgtata gtgatgcagt tttacattca
    31381 tataaataca gacactattt atttggagtt cagtatgatg aatataataa gagaaaacat
    31441 tatatttatg ctatcccagg aaatagaaat gaacagccag acaatggaag cacaggattt
    31501 ttaagatatc aagcttgtga taatagaaca aatagtttag gatattggct atgttttata
    31561 gattctagac aaagaaatat agttaggtaa aaataataaa aatgaaaaaa tttagactca
    31621 attcttattt tactgaaaaa attaatgaaa tgtagtacaa aactttaaaa actattgata
    31681 atatttaaat attacactac aatatatctt gaaataccta ttatattatg gaggaaaatt
    31741 atgataaacg agcaaagaat tttaaatgag tttcttgaat tagtacagat agatagttta
    31801 tctttaaaag aggggaatgt tgctaaagta ttagttaaaa aattagaaga aataggttgt
    31861 tcagtagtaa tagacaatgc tggtgaaaaa gcaaatggag aaactggtaa tataatagct
    31921 acattaaaag gaaataaaga aggaaagaaa atattattta gttcacatat ggatacagta
    31981 actccaggta taggggtaaa acctatagtg gatgaagcaa atggaataat aaaaagtgat
    32041 ggtactacaa tattaggttc tgatgataaa gcaggtatag cagctatatt agaaggctta
    32101 agatatataa atgaaaataa catagaacat actgatatac aagttgtatt ctctatatgt
    32161 gaggaatgtg gattagttgg agctaaaaat ttagactatg gaaaaataga ttctgaatat
    32221 gcatttatat tagatagtgg tggttctcca ggtgaaataa tagtaaaagc tcctgcacaa
    32281 gatgtaataa atgttaaggt attaggaaag actgctcatg caggtcttga acctgaagct
    32341 ggaataagtg ctataatggt agctgccaga gcaatagaaa atatgaattt acttagaata
    32401 gacgaagaaa caactgctaa cataggaatt ataaacggtg gaacagctac aaatatagta
    32461 acaggagaag ttaatatagt tgcagaagcc agaagtctaa aagaaaataa attagatgtt
    32521 caaactaaac acatggtaga gacttttgaa aaagctgcga aagattttgg agctcaaatt
    32581 gagatagatg ttaatagagc atacacacca atagatgtta gtgaggattc tgaaataata
    32641 aaacttgcaa agaaggcttt ttcaaactta ggtatagaag gtcatactga atctacagga
    32701 ggaggtagtg atacaaatat attaagtaag aatggtatcg aagctataac tttaggaatt
    32761 ggtatgaaaa atgctcatac actaagtgaa catatagcta taaaagactt atatgattct
    32821 gctaaaatgg tagtggagat aataaaggaa gcataaattt aaataatagt gtataatata
    32881 tatatcgcct agcttaagct aggtgatttt tcattttata gaagattgat aatctctatt
    32941 gaaagcaaag agtatacatt tgcatataag agagtgttta atttatgttc aaatgtaggt
    33001 tcttaataat atttagattg tttcataagg gaggaataaa tatggaaaca aggtatgaag
    33061 aagcaaataa aataacaata caatcaatac tttggaatat agtattaaca ataattaagg
    33121 ttatagctgg tgttattggt aattctagcg ctatgattgc ggatggatta cattcagcat
    33181 cagatattat aagttctata ggagtactaa taggcaatta tgtatcttct agacctggag
    33241 atagagagca taattatggt catgagaaag cagagacatt agtatcattt gtgttatcaa
    33301 tattgcttat tttcgtttct ataacaatag gtatagaggc aattaaatct ttatttaact
    33361 tagatgcatt aagtgttcca tcaatattac cattagtagt atcagttatt tcaatcctga
    33421 taaaagagta tcaatataga ataacaataa aagttgctaa aaagataaat tcaccagccc
    33481 taaaagctga tgcttggcat cacaggtcag atgctttatc ttcagtagct gcttttatag
    33541 gtataggtgg ttctatttta gggtttaaac cattagaccc aattgcgtca gttgtagtgg
    33601 ctatatttgt agctaaagta ggaattagta tacttataag ttctgttaat gaattgatgg
    33661 atgtttcagt tgatgaagaa gagataaaag aattaaaatt tattgtagca gatacagaag
    33721 gtgttaaaaa tcttggtgat ataaagacta gaaaacatgg agctatggca tatgtagatt
    33781 tgactatatg tgtggatgaa aatttgacag ttaagcaagg tcatgatatt gctaccaagc
    33841 ttgaaaaaca tataataaaa catatggaat ttgtaaaagg tataacagtt cacgttgaac
    33901 catgtactaa ttgccaagga aataagtgta ataattaatt aaaacttaaa aaaaagtgta
    33961 aaaagttata taattgtttt atgattataa actctagggg tggttaaatg agcaagaaaa
    34021 gaaaactaaa gaaaaaagct gcaatattaa taggagtagt tgttttcttt ataatatact
    34081 ttatatcctt tagaatagga ataaatatgg aaaaggataa aagtgaagtg ccaaagaagg
    34141 tagaaaaaga agaagaagat aataggtctt taaggactca aataaaagag aagaagaagg
    34201 tttatatatc agataaaaat atagaaaaca taaaaattga agaagatatg tgggatgaaa
    34261 taaagttatt tttctcagat tttaagaaag taagaaatac tacttcttct tacgaagcag
    34321 tttatgaagg ttattctgat gatggagtta aattttctac tgaccttaac ttttttagag
    34381 tatatactgt aaataaagaa gaatattata aagtaccagt tagttctaag gatgctttta
    34441 agaaactttt agatgagagt atatatactt cgtttgacct tttaagtcat tataaagatt
    34501 ggaaagaggt tactataact catggaaaag aaattaaaaa agttcataga tggaaatttg
    34561 atgatttagc acataagatg atttcaaaga gggttgtagg aaaagttcaa cctgagaaaa
    34621 gtaaggaaag aagtgactat aattttacta taaatataaa aggtgataat tttgatgtaa
    34681 aagttgatac aatgggaaaa gattatgtaa aagttacttc taagaaaaat gtatcttact
    34741 atgaggttca tacaagttta tttgattacc ttaaaaatga gatatttgaa attggaaaga
    34801 aataagactt taagaaggct atcaaattag atatttgata gcctaaatta ttttatatat
    34861 tatttttcaa ccaacaagtc tgcaacctta taaattggac cagcaccagc agttattact
    34921 aaatcattat ccttaacatt ttcacgtaag tattttacta tatcttcaaa ttcttttata
    34981 tagatggcat ctacattgtt ttgatataat ttctcaacca agtccttaga atgtatatct
    35041 cctgggtctt tttccctagc agcatatata tctgttatga taactttatc agcagcatag
    35101 aatgcctctg aaaattcacc taaaagagat tttgttctag tataagtatg tggctggaag
    35161 atacaccata aagttgattt ttttaatttt ttggcagcag ctaaagttgc ttttaactca
    35221 gttggatgat gtgcataatc atctactact aaagcattct tatagtaccc tttagtttca
    35281 aatcttcttc cgacaccttt ataaattttt atattttttc ttatagtctc taagtcaata
    35341 ccagaaacaa gagctgccat tatggcagaa gaagcattgt atatgttatg aagaccatat
    35401 acagaaagtt caaattctcc taaatctctt ccttcatatt ctattctaaa tattccatga
    35461 ccactattgt caaagtgaat atcttttatt acagcatcat tgtcagaatc tctgccgtat
    35521 tttataatag tagctttaac atcatacaat atgtcatcaa tattttcatc atcgccattt
    35581 attatgaaat agccttctgg gggtaataat tttccaaatt tgttaaaaga agccttgatt
    35641 tcatctattc cagagaaata atcaagatgg tcttcttcaa catttaaaac tatagatatc
    35701 tttgggttaa aattaaggaa actatctaca tattcacatg cttcagttat aaagtggttg
    35761 gaattaccta tcttaacatt accacctatc atacttaagt taccaccaac tagtatagtt
    35821 gggtctaagt ctgcatattc aaagattgta gataacatag atgttgtaga agtttttcca
    35881 tgtgttccag aaactgctat agaattttta tattccctca tgatttggcc taaaaaagtt
    35941 gctctgttca ttaccaattt atttttttct ttagcagcca caagttcttc attgtctgga
    36001 tgaactgctg ctgtataaac aaccatattt acatcatctg atatattatc ttttttctga
    36061 ccaatataaa tagttgcccc ttggtcccta agtttgtcta ataggtatga ttcgtttgaa
    36121 tccgaacctg aaacttgata acctttattg atacatattt cagctaatgc actcatgctg
    36181 ataccgccaa ttcctataaa gtgtatattc ataataaaac cacctttctt tttaattaag
    36241 tcctacaata tgaactattt ctgtggtata ataatataat gttcaatatt ttataattaa
    36301 tatgcatata atattatatg tattttattt ttgaatataa taaaacataa gtaatattat
    36361 accacaataa gaattgttat gcattagtta gtttaacgtt atataaaggt acttgtagga
    36421 ggaaataata atgaaattta aaagaacaga gagaattgga gcaatagtta aaatactgtc
    36481 tgataatcca aataaaatat atactttaag ttattttaca aatcaattta atgcagcaaa
    36541 atcaacaata agtgaagatt tattagttgt aaaaaatgta tttgagaagc tacatttagg
    36601 taaagttata actatttcag gagcagcagg aggagtaaaa tatataccta aaacttctat
    36661 agcagaaaat gcagagttct taatggaatt atgcgagaga atatgtgaca agtctagaat
    36721 actatctggt ggttttttat acttgattga cctaatttac gaccctacaa tagctgctaa
    36781 gataggaaag atattcgcat caaatattga gtatgtagat gcagattatg ttgtgacaat
    36841 ggaaacaaaa ggtataccta tggcacttat gactgcaaaa gctatgaatt tacctctagt
    36901 tataataaga aaagatataa aggtatcaga aggtcctaca cttagcatga catatgtgag
    36961 tggaaacagt tctaaagttg aaagtatgag tttgccaaga aaagctctta aaccagatag
    37021 taaagttata attatagatg atttcatgag gggtggaggt actataaaag gaatggtaga
    37081 ccttatgaat gaatttggtg cagaggttat aggtactgga gtattcatat ctacaacgaa
    37141 tccttcagaa aaaatggtaa aagattatat ttcattgatt caattggatg ttaatggaga
    37201 taaaatagta gtagaaccaa acttaaagac ttttaaagat gaatatagaa atgaagattt
    37261 agacgaagaa gaagattcag aatttgaatt tgagatagat gaagattaat aaaaaaaata
    37321 tttagaaaaa tatgtaaaaa taaaaagagg atatccctag ttgttcatag aattatttaa
    37381 aaaacagttt atattaattt attccagcga taataatttt aatataaatt aatttctgtc
    37441 aaaatcaaag ggggatattt tggtatgaag ataactgacg taagagtaag aaaattaaca
    37501 gaagaaggta agatgaaatg tatagtttca ataactttcg ataatttgtt tgtagtgcat
    37561 gatataaaag ttatagaagg ccataatggg ctatttatag caatgcctag cagaaaagta
    37621 ggcgaaggaa atttcagaga tatagctcat ccaataaatg cagaaatgag acaagtttta
    37681 gaagatgcag ttttacaagc gtatcatgaa gcattagttc aatgggaagt agctgctgaa
    37741 taataataaa tatataaaat ggagagagcc cgaacattta ggctcttttt aaatgtagaa
    37801 tttctattaa aatatgtact ttttagtaaa aaagtgctat attattagtg ataatgtata
    37861 tgttgtatac aaattgttag ataaatgtat tataatgtat attgattaag agaataatac
    37921 gaataaaatt aaattagatt gaatggagtg tatcaatgaa ctttaaagct ataatccttg
    37981 ctgctggcaa aggaacaaga atgaagtcta aatacccaaa agttatacat aaagtatgtg
    38041 gaaaagaaat ggttaaccat attatagatg tttcaaaaaa atcaggggta aaagatactg
    38101 tcgtgatttt aggacatgaa gctgatgtag ttaaagaaaa gcttgcagaa gaaattataa
    38161 tagccatgca aacagaacaa cttgggacag gacatgctgt aaagatggct aaagaatata
    38221 ttaatgatga agatacaata gttgtacttt gtggagatac tccacttata aaagaagaga
    38281 cactaaagag actatttgaa tatcatatag aaaataaata tcatgctaca gttcttacaa
    38341 caagagttgg aaatccaaca ggttatggta gaataataag agataagaag ggtgaccttc
    38401 ttaaaatagt ggaacaaaaa gatgcaaatt cagaagaaaa gatgataagt gagataaact
    38461 ctggaattta ttgttttaat ggaaagagtc ttagagaagc actagatttg ctaaataata
    38521 acaattcaca aggtgaatat tatttaactg atactgctaa aataatgaga gataaaggat
    38581 taaaagttgg tgcatttgca ggttcaacta ttgaagaact tatgggcgtt aattcaagag
    38641 tagaattatc aaaggcagaa gaaattatga gacgaagaat aaatgaatct catatggtaa
    38701 atggagtaac tataatagac actaactcta cctatataga atctgatgtt atgataggca
    38761 atgatactat aatatatcca ggtgttatgt tacaaggaaa aacaaggata ggttcagatt
    38821 gtataattgg aatgaattca tctataacaa attcagaaat aggtgatggt acagaaataa
    38881 aaaattcaac tataattgat agtaaggttg gagaaaattc tactgttggg ccatatgcat
    38941 acttaagacc aaagagtgac ttaggaaata atgtaaaaat aggcgatttt gtagaagtaa
    39001 aaaatgctat tatagaagat ggctcaaaag catctcacct ttcttatata ggagatgcac
    39061 atgtcggtaa aaatgtaaat attggatgtg gagtagtatt tgtaaactat gatggtaaaa
    39121 ataaatttaa atcaatagta aaagacaatg cgtttatagg ttcaaattct aatttagttg
    39181 caccagtagt tgtagaagaa aaaggatata tagcaacagg ttcaacaata acacatgatg
    39241 tcccagatgg tgctttggca atagcaagag aaagacaagt tatcaaagaa ggatgggtag
    39301 aaaaaaagaa tcaaaaagac gaccaaagta agtaattatg tagtttatta ttttggctaa
    39361 aaaatttagc tcgaaattat tataaattat attcattagt attttaaaat tttcaggagg
    39421 gttacataaa tgaatactag cggaagcgag attaaaatta ttgcaggtaa ttcatcgaaa
    39481 gagttagcac aaaaaatagc tgactatata ggtgtatcag tactagattg tgaagtaggt
    39541 acatttagtg atggtgaaat atgtgtaaac atgaatgaga cagtaagagg ttgtgatgtg
    39601 tttgtagtgc aatctactaa cagcccagta aatgataact taatggagtt attaatctta
    39661 attgatgcgt taaagagagc atcagcaggt agaataacag cagttattcc ttactatgga
    39721 tatgcaagac aagacagaaa ggctaaggca agagatccaa tcactgctaa attagttgca
    39781 aatttaataa ctgctgctgg agcagataga gtattaacaa tggatttaca tgcagctcaa
    39841 atacaaggat attttgatat accattagac cacttactag gtggaacaat attagcaaat
    39901 tattttaatg aaaagaaaat agaagattta gtagtagtat ctcctgactt aggaagtgtt
    39961 actagatcaa gaaaatttgc taatacttta aatggagaag ttccaatagc tataatagat
    40021 aaaagaagac cgaaagctaa tgtttgcgaa gttatgaact taataggtga tgttaaaggt
    40081 aaaaatgtta tactattaga cgatatgata gatacagcag gaacaatagt taatgctgca
    40141 aatgcactta aagagtttgg agcaaaagat gtttatgctt gttgtactca tggtgtgtta
    40201 tcaggtccag ctattgaaag aattgctaat tcagaaataa gtgagttaat agttcttgat
    40261 actatacaac ttcctgaaga gaaaagaata gataagataa agataaaaac agtagctcct
    40321 ctatttggag atgctataag aatgatattc tctaatgaat cagtaagtaa attattctaa
    40381 tttattgtat ttatgagagt tgtttaaaag gatataaacc ttttgagcaa ctcttttttg
    40441 attttatact tatggaatgt tatttttttc ttgttagaaa ggtatatatt attgtaaaaa
    40501 gagattatag tttaaaatta tgtatattta agtaaaataa acctaataaa gggtatatta
    40561 ttcaaaatat tatgaatata aaaaatatta caaaaaagta ttgaaaaaat tcagattatg
    40621 tagtattatg taaatataaa taaagaaaga ggtgtttcca atgggaaggt tagaagatga
    40681 acccctaata attaaatgat tcagtcacaa tctaaagtga atataaaaat ctattgaaag
    40741 tttatttata agaattgaaa atagtatcta ttctatcttt agtgtttgtg agagggttct
    40801 ggattatata agattactgt aaagagtaat tttgcacaat aagcatatct gtaaatgaag
    40861 agtttcgttt atataatgat tgtggctgaa tcataactat aatagataga atgtttataa
    40921 tagatgattt tataaaatac tatattgtaa tagcttttag ctttcaaata aatattagca
    40981 aaggatggaa atgacaatga taaaactaaa tgataattta taaatatctc cttacgatat
    41041 ataataattg tagggagatg tttctttttt tttgtatagc ataatttttc tagaaattct
    41101 gtttcaatat gtaaaaagtt ggtatatata aatagtataa acagtgttgc taaaatatgg
    41161 tagatattat ataatataag tggatatgta tatacattat gagttatata atttgaattt
    41221 aataaaatag aaacgttgat ttatgttctg taatgtgggc accttggagc atattgagtt
    41281 agtggtgcaa ccggctatga aattgtattt atttataaat actattattt tcatagcttt
    41341 ttttatttaa aaaatggtta tatgttagaa ataaatttgg ttagtacgtt taaataattt
    41401 tacttagatt tttaaccaga tatattgtaa gtaagtatta attaaaaaat ttaaggggga
    41461 ataaaaatga agttaaaaaa gaataaaaaa ggtttcactt tagtggaatt attggtagta
    41521 attgcaatta taggtatatt agcagtagtg gcagttccag ctttatttag taatataaac
    41581 aaggctaagg tagcaagtgt tgagtctgat tatagctcag ttaagagtgc agcattatct
    41641 tattattcag atactaataa gataccagtt acaacaactg ataaagctgg tttaactatt
    41701 ttagagactt atatggagtc tttgcctgat aaagctgata taggtggaaa atataaattg
    41761 attaaagttg gtaataaatt ggtattacag ataggtacag atactgaagg agttacatta
    41821 acagaagcac aatcagcaaa attattgagt gatataggta aagataaaat atatacaggt
    41881 gttacaggag ataattttgg agacgaatta acagatacta caaaaataga taataaagct
    41941 ctatatatag tacttataga taatactgtg atggactcaa caaaataatt aaaactatat
    42001 ttttataaag aatattgtaa atttaatgaa aaatataata taaaagacag gaagaaaatc
    42061 ttcctgtttt tttatactat tttctttaat gttcaattat gaatgatgat ataattgaga
    42121 tagtaaagga gtgaaacctg tggctaaaaa agttagaata ggagacaaac tggtcgaaaa
    42181 aggatatata acagaagaac agcttaaatg ggcactatca gaacaaaaaa acagtggaaa
    42241 aagactagga gaatttctag tacaagaagg gcttatagat agtaacttac taataagtgt
    42301 attaaaagaa ctcttggata tagaaagtat atttttagaa gggacagaaa tagacacttt
    42361 agctacaaaa atggttccag aaaatatatg caaaagatat actgtatttc catttaaaat
    42421 tgatggaaat aaaatatgtc tagccatgtc agacccacaa gatagagaag cagttcaaga
    42481 tgtaaggcgt atgtctggta aagacgtaga gatatttata tcaagtacag aagatataaa
    42541 caaagcaata ggtcatgctt atgcacattc agaaataaat aaggcaatga ctgagtacaa
    42601 caaaaataga actggtggag taagagaaac agtaatactt gaagaagatg taaatgctgc
    42661 tccaatagta cgattagtaa ataacatact agaaaatgct gttagaatgg aagcaagtga
    42721 tatacatata gaacaaagtg aaaattacat gcgtgttagg tttaggatag atggaatgtt
    42781 aagagaatat atgaggatga actcagcacc atataaggca gtaatcagcc gtatcaagat
    42841 aatgtcagat ataaatatat ctgaaaagag aataccacag gatggtagaa tctatttaaa
    42901 agtagataat aaacccatag attttagggt ttctacaatg ccaactaaca gggatgaaaa
    42961 gatagctatg agggttcttg ataagagtaa ttttatggtt agtaaagaag tactaggaat
    43021 agacgaacat ggctctaaga tatatgatga attgataaac actccttatg gtcttatatt
    43081 ggttgttggc cctactggaa gtgggaaaac cactacattg tattcaatgt taaatcaact
    43141 aaatacagaa aatagaaatc tattaacaat agaagaccct atagagtatg aattacctgg
    43201 tgtaaatcaa tctcaaataa atgaaaaggc agggcttact ttcgccagcg gacttagagc
    43261 ttttatgcgt caagacccag atataataat ggttggagag ataagagata ctgagacagc
    43321 agaaatagca attagagctt ctcttacagg acatttagtt ttaagtacat tacatgcaaa
    43381 tacagcagtt ggagcaattt cacgtctttt agatatggat gtagaaagtt ttttaataac
    43441 ttcatctgtt ttaggtgtaa tatctcaaag acttacacga aaaatatgtg agcattgtaa
    43501 ggtttcatat gaagcagata ttggagaaaa aaaggctctt ggtattgatg taaatgaatc
    43561 agtaactatt tatagaggaa aaggttgtga aaggtgtaat aatactggat ataaaggacg
    43621 tctaggtata tttgaaatgc ttgaaattac tccagaaata aaagagttaa tagattcatc
    43681 tgcaaatcaa agagaaattt taaagatggc tagaaaacaa ggtatggtta gcttaaaaga
    43741 ggatatagtt aaaaaagttt taaatggaaa gacaacagta gaagaaatga ttagaataat
    43801 tttgatgact gattaaagga tgatattatg aaaagtttta aatacacagt aataaaagag
    43861 gacggaaaaa agcaaactga tgtgattgaa gccaacgatt ttaatgaagc tagaaatctt
    43921 cttagaaaga gaaatcttag agttattgaa atcaaagaaa gcaaaaataa aaatataaga
    43981 ttatctagta gaaagagaaa aaaagacttg ggagctgacc agataagcca cttttgcaga
    44041 cagtttgcta ttatagtatc ttctggtata aatagtattt ctggattaga aacattagct
    44101 agaaggtcaa ccaacattac attaagagaa gaaattaatc gtatagtggc agaaataaaa
    44161 gtaggttcta ctattgcaga ttcaatgctt tcatcaaaat caaagtttcc aaagttactt
    44221 ggtgctatgg tagctacagg tgaagctaca ggtaaattag atgaagtatt aaaaagtatg
    44281 gcttcatttt atgcaagtga acacagggtt aaacaaaagc ttagaaatgc tgcaacatat
    44341 ccattaatag ttttgatttc ttcatttata atgattttta tatttacaac atttatggtg
    44401 cctaagatga ttaattcaat tacaacagta ggagcaactc ttccacttat aacaagaatt
    44461 gttatggggt ttggtatgtt tatgaagaag ttttggataa tagtactttt agttattata
    44521 ttatttatct atcagtttaa aaaatatcta aaaacgtcag ttggaagggc tcataaagat
    44581 agagttataa ataagatacc tgttttagga aaaggaataa attgtatggt agctacacga
    44641 ttttcaagag cattgtatct atttgtatca acaggatacc cattagttca agggcttgat
    44701 tatattatag atagtgtaaa taacactatg gcagagaaga ttttagcatc agctaaagat
    44761 ggaataacaa gaggagaagg cttagcagaa aatttagaga gatatacgta ttttgactct
    44821 gtgttggtac agatgatagc tataggggag cagacagggg aattagagaa tataagtaga
    44881 cagatggcag aattttatga gtatgaatcc gagatttatt taaataggat ggcctcaatg
    44941 atagagcctg ttttaataat tgcagttggt attatagttg cgatactggt tgtatcaata
    45001 ttcatgccaa tgcttagtat atatgatgcc atgtaggagg gaaaggacaa atgaacaagg
    45061 tttatgtatc atattatggc gattctattt ccatagttga gggcagatat aaacacgata
    45121 aggataagtt ttatgtaaaa aattttaatg tgttttcaat agaggatatt gcacaagatt
    45181 tttctaagga aaagtatgct ctattgagat acgcattaga aaatgttaag ttaaaatcaa
    45241 gacatgtagt tttttgttta aatacaagag atgtaatttt aaaaccccaa aaacttccta
    45301 atatggacaa aaaggattta gacggattta tgaagctaga gatggacgaa atgatggctt
    45361 tggagtcaga tgaatatgta ttttcgtatg aagtatctag tgaaacacct gataattcag
    45421 atggcgatga atcaagttta aatcttatta ttggagctat acaaaaggaa gaggtaaatg
    45481 caattgtaga gataatgcat gaatttgatt tagtattaga tagaatagat acattatcaa
    45541 cagcttactt aagaatgctt aaaaatttag actacaatga tataatggta accaatataa
    45601 gtgacaatag cacaattata aatatatata agaaagatac tttatttatt agtgataata
    45661 tacctataaa gataactgct aaagatatgg acatgcaatt attaaatgta gtagaagaat
    45721 caaaaggtct tatgaattac tattcgtcaa gaaactttgg taaggttacg gatactatat
    45781 taatattagg aaaaagatat tccaataaat taatttatga aacttttagc tctgcatttt
    45841 caagctatgt ttctcaaggc cttactgaga taatggatat atctgatatg ataactggag
    45901 atatagatga agatgatata aattcaattg tagagctttt aggaagtatg atagaaccta
    45961 aagggaaaag agattttgaa aatataaact ttttaccaat ggatatactt agaaaacaga
    46021 taaaagctaa acaaatgaaa aacatactga aaattgctcc aatagttatt ttgattcttg
    46081 ctatacctta tttatgttta attttttcaa ataatttagc aaataaggaa cttgaaaatg
    46141 ttaatggtga aataagaaat attgaatctg catattatca gattggaaat atagaaaaaa
    46201 tgatacagag taaaagcgaa gaaataaagg tatatgatat gttaattggg aaaaaggtaa
    46261 agtgggaaaa tttattggat gatatagata aaaatactcc aagtaaagtt gaactaacaa
    46321 gtttatcaac aacttatcaa aatcttggaa ctaataataa agctgataat tcaaaaagta
    46381 ataagactac aacagataaa tcaagtaaca atgaaacaaa atcaagtacg aaaagtgata
    46441 gtaatggaga taaaacagat aatgatttaa atgaagataa gactacaaat gtgtcagaag
    46501 cattaactgg aaatagtgag actaatagta ataacacaga taaagatgat aaaactccat
    46561 tgtatgataa gataccaaat gttataaata tagaaggaaa tgctaaagat tcctcttatg
    46621 taggtcaatt tttatataaa ttaaagggat tatactattt caaggatgtt aaattacata
    46681 gcataaaaag taatgcagaa gattctaact atacatttag tatgacatta tacctgaaag
    46741 aaggtgtatt aactaatgaa taaagatata tttaaaaaag atataaaaga tatatttaaa
    46801 atggaagtta gtctaaaagg gattcttata aaggttataa ttttattagc tattttatca
    46861 tatggttatt ttggacttta ccctcaatat cagaaatata ttgctacaaa aaattctgta
    46921 aaacaggcta ctgaaaaatt aaatatatat aaagagaaaa ctgcacttat gccaaaatat
    46981 gaaaaacaac ttgaagaagt tgaaagtgaa ttaaaagaaa aaagcaaaaa tcttttatat
    47041 gatatgcaag atggtctttt tttaataggt ttagataaaa aaatgaaggc ttataatatt
    47101 gacttaacca gttatgacgt tggaaatgtt aaagaatacg aacattttta tggtatatca
    47161 acaacaataa gtgttagagg tgattataga aatgtcaaaa aattaatggc ttatttagaa
    47221 gaacaaaaaa atgttactca aatactagat tatacaatga cttcatatat agaaccagaa
    47281 aaagaagagg aagaaacaac aaacaataag gatttaatta aaaatgtgaa cataaataaa
    47341 gatacaaaaa tatactgggt ggaaggcgaa aataagtggc atttatataa ggattgtcca
    47401 ttgataaaag agggagagat tctaaaaaat gacaaacttt tagataggtc tactaattat
    47461 ctatgtaata cttgtgtact tagagctgca acagaaaaag aagcaaaaaa agaagtcgta
    47521 gctccaaagg cagaaggtgt agtagatgct acatttaaat ttataatgta cactaaagag
    47581 aatactacaa tgatacttga tacagataat ccatcttcat ggagaccagg aaaatataat
    47641 ccatttaagt ctagtgcgaa ataaagctaa gtaagcttta aagataggtg atgagtttgt
    47701 acaaaaataa tgaaaaaggt cttactttat tagaagtaat aatagctgtt tttatactga
    47761 caatagtttt aagtatttct tataaagtgt tcaatggtat aacatcagca gtaaaaaagc
    47821 aacagattat tacagatgct caagtaaata ttaatctaat taataagtat ctaaatagag
    47881 atttggaaaa ctgtaaagaa ctaactaaaa ctggttcagg taataattat gaatacaata
    47941 tagagatgcc agataatgtt gtaaaatatg aagtttctat agaaactaaa aaaaatacag
    48001 aggtatattc tgtaacgaga atccaaaaca atacaattga tacagaaaat gaagttagag
    48061 aagagataat ctataatcaa ccactagttc aaaacaataa agaaatgaag gaaacaccat
    48121 ttaaaataga aaagcaaact ggtaaatcta tttatactgt aagtatatac tataatgaat
    48181 cagtgcaaga aagtcataaa aatagcaatt taaataacaa aacttataca tttgatgtta
    48241 tgtcaagaat aggataataa gaatttatta aaaaataagt aggttgataa aatatgagta
    48301 aaaagaatag tgaaagagga ttttccttaa ttgaagtgtt agtagctatg gctattatgg
    48361 gaattgtact atttgcattt tttaatatta tcaatactaa taacaaagca aacactaaaa
    48421 atgacacaga tataacttcc ttaaactatg tccaaagtga aatagaaaat ctaagagaaa
    48481 agataaaaag tggagaattt gattttgata gtttagataa actagaagat ggaactgtcg
    48541 tatatgaaaa attaatagat aaatcaaaaa aagttgtata tgataaagtt cttagtgaag
    48601 gtgatgtgag cttatatgat actccatatg aaaagattac aacaataaaa gatgaagatg
    48661 gtaatttaat cgacaaagga aatattacaa ataagataaa gactattgta gaagataaaa
    48721 gtggtcagat atataaaata gctgtaactg ggaaaagcat gaatgactat tcaagtaaaa
    48781 aagaggttaa aattgtaact gaaatattta aagataaata attttacttg ggggtgagat
    48841 tttgaggaag tggaataaat ttaaaagtga aagaggggca gctttagttt tagttttggt
    48901 tgtagtagca ttgctttcta ttgttggatt gatattttca aatcagatag ctaatagaat
    48961 aaaatctaca aagactacta atgaaggtat acaagcaaag tatttagcag agacatgtgt
    49021 ggaaaatagt attgataaag catatgaaaa attgtatgat gagcttgaga aaatggataa
    49081 tgagtttaaa agtgaaaatc aagaaaaatc catatctagg tcaaaattaa gagatatatc
    49141 agatgaagat tttaataatc aagatgagga aaatattgaa gcagaaagac ttggatatat
    49201 gaataatata aatttctatt taaataaagc ttcttcagac ttggaaaaag ctagtatgga
    49261 attgaaaaag ctatatgatt tagatatgtt ggactataga gacattgaat atgtagatgc
    49321 aaatattatt tcacatagag attctatctt agaaatttgc aagaattata cttctggaga
    49381 tattagtaaa ataaatgaat atattctgaa agaagatata gactcaacta cattgattga
    49441 ggcaaagtta gtgaataatg atattctttt aaaaatgttt ttagaagaaa ataaaattga
    49501 aaatgaacat ttaaattcag ccttttcaca tacttataag gcattagata acatttcttt
    49561 ggcgatgcaa aatatgattg agtatagaca tacgtttcat atagatgagc caaaagtaga
    49621 agtatctaat gggattccag attctcaaca atattatgaa ctaatacaaa atcctataat
    49681 aaatagtatg gagtatatct ggaatagtaa atgggataca ttagaaaaac tattggaaat
    49741 tttaccaaat caaactcaag gatttaattc tttaagagtt catttgagaa ataatgtaag
    49801 aaaatttgag aagttaagcg ataatatatc tagtggtaaa aaaaatacag caaaaaattt
    49861 cttaaagtat aaagagttat tgtatgaaat atcagaccaa tgtaatcaac taaaaagtat
    49921 gtcttatgag aaaatacctg ttaaatatga taacatggct ttgataacaa cttttgacta
    49981 tatacaaaat gagcttttag cagagataaa atgcagatta aaagaattaa aaccacaaga
    50041 aattgataaa acagaaggta ttactataaa aatacctttt tataaggctg actacgacat
    50101 gacaaaagaa ggatggccta aattaaaaga aaatggttca ggggcggagt taagcttaat
    50161 ggtaactggt gataaagatg gaataaaaga agtagaagtt acagatggta aaaaaaatat
    50221 tattggttta ggtgttgaag aaaattcaaa ttcaaagtat aaggttgacg ccattgtaaa
    50281 ctttaatcta aatatagata caaatgtagt tggaaattat gatataaaag ataaaatttt
    50341 gattaatcat gatataagtt catacaaaaa agtaaactaa atataagaag caacttagta
    50401 taaataaata ataaaataat tttattattt actactaaaa aaataagtaa actaatagaa
    50461 gatatggaga gtaaatatta tgtatattta tgatttatta gagcaaggta taagactaaa
    50521 cgcatcagat atacacataa cagttggaac aaatcctgta gctagagtaa aaggtggatt
    50581 tgtaaaacta agtgaacaaa tattgacatc agaagtaaca atgcaaatgg caaaagacat
    50641 agcaggggaa tctatgttta aagtaataga agaacatgga gaagctgatt tttcagcttc
    50701 tttaaaaaca ggagaaagat ttagggtaaa tgcatatagg caaaaaggaa attacgcaat
    50761 agcaataagg actataacag cagaaattcc aacatttgaa aaattaggcc ttccagagag
    50821 tataaaatct tttactgaaa agcataaagg attagtttta gttacaggtc caacaggaag
    50881 tggtaaaagt acaacacttg caagtatgat aaatataata aatgaaaaac aacaaaaaca
    50941 tataattaca cttgaagacc cgatagaata tgtacatcat cataaacaaa gtttagtaaa
    51001 tcaaagagaa gtaggaactg atacagaaag ttttcattca gcccttagag ctattttgcg
    51061 tcaggaccca gatgtaatac taataggaga gatgagagac cctgaaactg tttcaatagc
    51121 attaacagca gcagaaacag gtcatttagt attttcaaca ctacatacag tgggggcagc
    51181 taagacaatt gatagaatag tagacatgtt tcaaccatcc caacagcaac aaataaaaac
    51241 acagttatct acagtttgtg aaggtgtggt atcacagcag ttacttccta cagcagatgg
    51301 gaaaggcaga atagcagcaa ttgaattgat gtttgctact ccagcaataa aaaacctgat
    51361 aagggaaggc aaaacatatc aaattccaaa catgatacaa actggagtta aagtaggtat
    51421 gaaaactatg gaccaagatt taatggaact ttataaaaat ggaaagatta caaaagatat
    51481 ggcacttagt aggtgtactg accaagagtt tatgacaaga atgataggtg gagtaaacta
    51541 caatggatat tataatcgtt aatctatatg tatttatggt gggtatagtg tttggaagtt
    51601 tctttaacgt ctgtattttt aggattccag aaggtatatc tatttctaga cctccttctc
    51661 attgtatgag ttgtaatact agactaaagc caatagactt aataccagtg ttaagctatt
    51721 taatgagtgg cagaaagtgt agatattgtt atgagaaaat ttctagtaga tatgctatag
    51781 tggaattaat tacaggactt ttatttttaa cagtatttat gttatatgga atatctacat
    51841 caactattta ttatttggtt cttgtgtctt tactgattat aattacattt atagatattg
    51901 accactttat aataccagat aaaatattgg tttttggagc tatattttct atgattttta
    51961 accttttatt taaagaaatt ccagttaagg attcaattct aggtgttttt atttgtggag
    52021 gaagtgtctg gattatagtt cttttgattg aatttgtaat aaaaaaagag tgtatgggtg
    52081 gaggagatat caaactattt gcaatgctag gtttttacat gggtgttaaa aatggtcttt
    52141 tgacagcctt actaagcgtt tatgtgggag cagtctatgg aatctgtgta ataattataa
    52201 gtagaataaa aggaaaggaa tataattctg ttataccata tggacctttt atatctattg
    52261 gagcattaat aacaatctta tgtggaaagc aattacttga actttatttt tctatggtta
    52321 tatagatgat agtcaagtta aataaagttt taatttaaaa aaatgaatta aagtatttaa
    52381 taaggacaat attattatta accctattac taaagtgcta caaactatgg agtatataat
    52441 aataatttcc ttattttttg cacatttgat aaataaatct ctatgtgttt tttgtgatag
    52501 agaaaagaaa aatttataca atacgttttt tatttacata ataactgtag ttttatctgt
    52561 attaatatat ctaaaatttg ggattagtgt agaatgtgta caatatatgg ttttaattcc
    52621 atttttaata attatatcca ttgtagatta ctacacaata tatgtatatg atataacaat
    52681 agttagtggt ataatagttc aaggtataat ttttttggtc tttttcaata tagttcaatt
    52741 tgattatata aatcatatat ttggactatt gataggcttt attatacctt atattattgc
    52801 taaactaaca aaaggattag gctatggaga tgtaggtctc tatagcttat gttgctttgc
    52861 attgggaaat aattatgggt tttatgtgat agttttatca tttattttag cgtttttgtt
    52921 ttttattatt ttatacataa ctaaaatatt taaagatgta gatataagaa agcaaattcc
    52981 ttttacacct tttatttcct tgtcaacaat tttaataata tttacagagt ataatatatt
    53041 taatttttat tataatttgt tatacaaatt tatataacag gaggtaagaa atgtacgtag
    53101 tagtagggtt aggtaatcca ggaaagaagt atgagaagac tagacataac gttggatttg
    53161 atgttataga tattcttgct aaagaataca atattagtgt tactaaaata aagcataaag
    53221 ctttgattgg tgaagggaga gtaggtactg aaaaagtatt attagttaaa ccacaaactt
    53281 atatgaattt aagtggagaa acattaatag atatatataa atattataag gttgatttaa
    53341 gtaatatagt agtagtatat gatgatatag atttagaagt tggaaagata cgtataagaa
    53401 aaaaaggaag tggaggaact cataatggca tgaaatctat aactaagtgc ctaggttcaa
    53461 atgactttcc aagagtgaga gtaggtgtat ctaaaccaga agctggtcaa gacttagcag
    53521 actttgtact ttctagattt agaaaagaag aatctgataa cataaatgaa gcattagaaa
    53581 aagcggcaga tgctattgac tcaataataa gagaaaatat agatatgtct atgaacaaat
    53641 ataatggata gtgagaggga gatttaaatg aatgatgttt ttttatatcc tttgcaaaat
    53701 tcaaaagagt ataaagatat aataaactgt ataaaaaata caaaaggctc attattggtt
    53761 aatggacttt taccagtaca aaaacctcat atatcgtatt ctatatttaa tgatttatca
    53821 cgacaaatga tttttataac aagtagtgat ttagaagcaa agaaagtata cgaagattta
    53881 agtttttata tggaagataa agttgaatat ttaggttttc aagatattta tttttatcac
    53941 ttggatgcaa aggacagaaa cgaagaagcg aagaaattaa aagtattgtt aaaactagca
    54001 aataaagaaa aaatcatttt agtaacttct attgaggcag ttttaagaaa atacatacca
    54061 aaacaagttt tgctcgatag tgtatctcat tataaggtgg gagatagctt agacttagaa
    54121 aagttaactg agaaattagt ttcattggga tatgaaagag tttcaaaaat agaggggttt
    54181 ggtcaattta gtataagagg tggaattatt gatgtatttt cacttgaata tacaaatcca
    54241 attcgtatgg aattatttga tgatgagata gattccatac gaacttttga cgtatattca
    54301 caaaaatcaa ttgataaatt gcaacaattc tctataactc catctaggga atttatttat
    54361 cccgaaaaaa ctacagatgc attagttaaa ttaaaaaaag aaacaactaa aaatactgat
    54421 gaaggtacat ttcaaaatat agattatata tcaagtaaga cttattttga aggtgtagag
    54481 aactatatag attatattta tccagaagaa aacaaaagta tatttactta tttagcagat
    54541 gatgcaatag tatttattaa tgatataacg agacttaaag aaagatgcga aaattatata
    54601 aatgagttta gagaaaatta taaattaaat cttgaaagag gtctggctat taaaaaccaa
    54661 ggtaaattgt tatatcacta tacagattta gagtacttag taaaagacaa gtctgtggta
    54721 ttaaactcgt tattgccaaa gtctataaat aacttttcta taaaatctat aataaatttt
    54781 gaaagtagag aagttcctac atttaatgga aaggtagatt tgcttgtaga agaattaaat
    54841 cggctgaaat ataatggata caaaataatt ttagcaacaa ataccttaga aagagcaaat
    54901 aaattaggaa aagatttatt ggacaaaggc ttagaaacga ctatttctaa agatagagat
    54961 attgaaatta aatcttcaca agttataatt gtacctgcac acataaacag tggttttcag
    55021 tataaatcta taaagtttgt tgttataaca gataacgaaa tgataggtgt ttataaaaga
    55081 gcgtctaaga ctagcaataa aaaagttaaa aaaggaaaga aaatagaatc ctttttagat
    55141 ttaagtgttg gagactatgt agttcatgaa aatagtggtg taggtagata cacagggatt
    55201 gaacaaatta cagtcaatgc tattaaaaaa gattatatga aaatagtata tcaaggtgga
    55261 gataatctat atgtgccaat agaccagatg gacaaagtac aaaaatatat tggtgcagaa
    55321 gtagaaaaag ttaagttaaa taagcttgga acaaatgagt ggacgaaagc aaaagcaaaa
    55381 gttaaaaaag aaattgaaga tatgacaaaa gacttgattg agctttatgc aaaacgtgaa
    55441 aaaatacaag ggtataagtt ttcaaaagat acaccttggc aggcagagtt tgaatcgttg
    55501 tttccatatc aagaaacaga agaccaatta aaggctatag aagaaactaa aaaagatatg
    55561 gaatcaagta aggtaatgga taggctagta tgtggagatg ttggttatgg aaaaacagag
    55621 gtagctatta gaagtatttt taaagcttgt atggaccaaa aacaagttgc tgtattggtt
    55681 ccaacaacaa tattggccca acaacattat aatacattca aagagaggtt tgaaaattat
    55741 cctttgagag tagaagtttt aagtaggttt aaaacaccaa aacaacaaaa acagattatt
    55801 gaagatgcta aaaaaggatt agtagatatt ttaattggaa cacatagaat aatatccaaa
    55861 gatataaatt taccaaactt aggtcttgta gtcattgatg aagaacaaag atttggagta
    55921 aaacataaag aagctttaaa gaaaattaaa tctacagtag atgtacttac actttcagca
    55981 actcctatac caagaacatt acatatgtct ttaagtggaa taagagacat gagtgttata
    56041 gaagaacctc cacaagaaag acatcctgta ataacatatg ttacagagag taaggaaagc
    56101 gtaattcaag atgagataga gagagaatta agtagaggtg gacaggtatt ttttgtatac
    56161 aatagagttg aacacattga agaaatggca agtatgattc aaaaactcgt accagatgct
    56221 agagtggctg ttgcacatgg aagaatgact tctaaatcat tagaaaatat aatcctagga
    56281 tttttaaata aagattatga tgtactagtc tgtactacaa taattgaaac tggtatggac
    56341 atatcaaatg caaatacaat gattatatat gatgcagata aaatgggatt ggctcaactt
    56401 taccaattga gaggtagggt tggaagaagt tcaagacaag gatatgcata tcttttgtat
    56461 gaaaaagata aaactttaag tgagatagcg gagaagagat taaaagctat cagagaattt
    56521 acagagtttg gttctggttt taaaatagca atgagagacc ttgaaataag aggagcagga
    56581 aatattttag gttctcaaca acatggtcat atggcagtta taggttatga tttgtacgtt
    56641 aaaatgctta atgatgcaat taaaaaagtc aaaggtgaac ctattgtgga ggaaattgat
    56701 gttgaaatag atttaagtgt aaatgcatac attccagata attatatcaa agatgagttg
    56761 attaaaattg aaatgtataa gaaaatagct tctattgaaa acaaagaaga catgttggat
    56821 atacaagaag aacttgagga tagattctct gatataccta aaccagtcca gacacttctt
    56881 acaatagctt atataaaatc gttatgtaag atattaaaaa tagaaaagat aagacaatta
    56941 aaagatgaaa tattattagt tccaataaca aagtatagaa ctaaacagaa aataggttat
    57001 aatatagtta cagaattaga agaattatta gaaaagatgt gcaaggtaaa ataacttgta
    57061 aatttaagaa gggatgtttt aaatttgaaa aaagtaataa cattggtaat agctatgatt
    57121 ttggtagtat ctgtgactgc ttgcagttct agtaaaggag aaactgtggc aacagttgaa
    57181 ggtacaaaga tatcatcaga tgaatttaaa aaaactatag ctctttataa agattctatg
    57241 gaacaaactt atggaaaaga tatatgggat aaggaagttg aaaagggtgt aaaatacaag
    57301 gacaagttta aagatttaat tcttgaccaa cttataacta cagaagtaat atattctcaa
    57361 gctaaaaaag ataacttact tcctaaaaaa gaggatgttg aaaaaagttt taaagaatta
    57421 aaagacgcta tgggtaaaga tgaaaaatat aaagaacaac ttaagaaatt aggtatagat
    57481 gatgagtttt taagagacca acaagagaaa gatttagcaa tgcaaaacta tcaaagtaac
    57541 tttgctaaaa agactaaaat atcagatgaa gaaatgaaaa aatactatga tacacataaa
    57601 gatgaattta aaaaagatga ggtagaagct tctcatattt tattgaaaac agtagatgat
    57661 aataacaagc cactttcaga taaggaaaaa gctgaagcta agaaaaaggc tgaagaggct
    57721 cttaaagaag ttaaatcagg tgaggatttt gcaaaagtag caaaaaaata ttcacaagat
    57781 acttcagcaa gtgatggtgg taaattagga ttcttttcaa ggggtcaaat ggttgctgaa
    57841 tttgaagatg ctgctttttc tatgaaaaag ggtgaagtat ctgatttagt tgaaactcaa
    57901 tatggatacc acataattaa agtgacagac agaataaatg agcaaacatc atttgacgat
    57961 gctaaagaaa ctataaaaga ccaactgttg aaaaataaat atcaagaaca aatagaaaaa
    58021 ttaactaaag aagctaaggt agaaaaagat gaaaaagtaa taaataaaat cacaatctaa
    58081 gacttaaaaa aagagtaata tgcttaaaaa agctatatct ggataagata tagctttttt
    58141 tgtatatttt tcttaacaat ggtaaaaata aacttaaagt aatttatgga gggattaaaa
    58201 aatatgaaag caacaggtat agttagaaga atagatgatc ttggaagggt agttatccca
    58261 aaagagataa gaaagacatt aagaattaga gaaggagacc ctttagagat attcacagca
    58321 aaagatggag aagtcatact taaaaaatac tctccaatag gtgaattaaa tgaattttcg
    58381 caagaatatg ctgaaacatt agctgaagta ctaggatatg gagtgttgat aacagactta
    58441 gattctataa tagctgtatc taagcttcct aaaaaagatt acaaagaaaa aagtataagt
    58501 gatgagttag aagcaataat aagtgaaaga acagtaaaat attcaaaaga taaaaacatt
    58561 ttaccattat tcaaggaaga ccaaaaagaa tatactagtc aagttatcat gcctataatt
    58621 agtgcatctg gtgactgtat aggttcaatt gtagttgttt caaaggataa agatacaatt
    58681 gcagaaagtg aagaaaaatc tttaaaaatt gctgctaact ttttaggaaa acaagttcaa
    58741 taattttatc ataaagacct tttacatgaa ggtcttttga agtttttgtg taaaatattg
    58801 aatatagcat taaaaatatg gtatattaaa gtttgttata taaacagtat ggaggttatg
    58861 ttatgaacaa taacaaaaat aaagactcct ttctaaaagg agcccttata cttgggctag
    58921 caggtgtaat cgtaaaaata atgggtggat tttttaggat tccccttgga aacatgattg
    58981 gttcagaagg aatgggatac tatcaggctg cttatcctgt gtatactcta tttttaacat
    59041 tagctactgc tggatttcca acagctgtgg caaaattggt ttcggaaaaa gttgcaattg
    59101 gaaattttaa aggtgcaaat aagatattta aggtatcaca tacagtttta ttcattaccg
    59161 gtataatatc attttgtata ttattttttg gagccgacta catagtaaca aacgtaatga
    59221 aaaatccagg tgcgttatac tctatgaaag ccattgctcc agcattacta tttgttcctg
    59281 caatgtctgc atatagagga tattttcaag ggagacaaga tatgactaag attgctgtgt
    59341 ctcaagttgc agagcaattt tttagagttg tattaggtct tactttggcc tacttgctta
    59401 tgaagagtct aggtcagact tttggtgcag caggtgctat atcaggggct acaataggtt
    59461 caatagcatc tatgctttat ttggtgtttg cttatatgct agggagaaaa gagcgtagag
    59521 cagagataga tgcaagccaa agatttaaag atgaaagagt gtcttatatt tttaaaaagc
    59581 ttttaactgt tgccattcct ataacaatag gagcatcagt aatgccactt gtaaatatga
    59641 tagataatgt tattgtaata agaagactta tggaagcagg atttacatac aaagtggcaa
    59701 attcaatgtt tggtcaatta acaggtatgg caatggccac aataaattta ccagcagtca
    59761 taacaactgc aatgagtatg agcttagttc cagcaatttc taaagcatat gcattaggaa
    59821 ataagtcaaa agctagaaaa gatactaaga gtgcagttaa ggtaacttta cttatagtat
    59881 tgccttgtgc gtttggtatg gcttctttag caataccaat aatgggtctt ttatttccac
    59941 atgaaccatc ttctgtagga actattttgt ttactcttac tccatgtgta ttatttttag
    60001 gattaataca gacattgact ggtataattc agggaatggg aaaaccaata gtacctgtaa
    60061 ttgctttatg tgttggtatg ctatgtaaaa ttgtaataag ttatacttta acaggtatac
    60121 cagatattaa tgtactgggt tcagcatttg gtacagttac agcatacttt gtggcagcca
    60181 tgattaactt actatatgtt aaaaaacaca tgaatgtaaa cttttctaaa aaagaattta
    60241 taataaagcc atttataaca gttatgacaa tgtttataat ggttaagttg agttatggtg
    60301 ctttagttgg attcttagga aacagcatat ctacaataat tgcaatatgt gttggtggaa
    60361 ttgtatatgt agtagtaata cttggaatag gtggaattaa aaaagaagag attctaacta
    60421 tgccaaaagg tgataaatta tataaattgt taaaaaaagt taaacttata agataatata
    60481 ggaatatata tgcaaataaa ggaaatacta tacaaatagt aaatctcctt atttgtataa
    60541 taatataaaa ataaagtgaa atttgctaat aggagtgatg ttatgggtaa gataagtatt
    60601 gtaggtcttg gaccaggaga ctattctctt ataagccaag gtgtgttaga atctttaata
    60661 aatagcccta aagttttttt tagaacagag aaacatccaa taattgataa acttaaagaa
    60721 actatacaat acacttcttt agactacttt tatgaaaaag aggaaaattt tgataatgtt
    60781 tatttgaaaa tatctgaatt tatcatagaa gaatcagcaa agggtgacct agtgtatgct
    60841 gttcctggtc atccaagagt tgcagagaag actgtaagta taatagagag attagccaat
    60901 gaaaagcaca tagcagtaga aatattgcct tctatgagct ttgtagacgc tatgtttaac
    60961 tatttggcta tagacccatc tgagggattt aaactggtag atgcttttga aatagaaaat
    61021 tcatatatag acttggatac aagcatgata ataactcagg tatatgataa atttatagca
    61081 tctaatgtaa agttaaaact tatggaacat tatgactata atcaagaagt atgtatagta
    61141 aatggagcag gtgtcaaaga tttagaaagt aaaaagttta taaagctttg tgaattagac
    61201 agaaatgaaa acttttttga ctatttaact agcttatata tacccaaaag ttctaaaaag
    61261 atgtataata cagtacatga cttagaaata atagttaata cacttagaag tccatctgga
    61321 tgtgaatggg ataaaaaaca aacacatcaa tcattaaaaa attctgttat agaggaagca
    61381 tatgaacttt gtaatgcaat tgataataat gatatagatg aaatggtaga agagttaggt
    61441 gatgttcttt tacaggttat attccattgt cagataggaa atgaggaggg ctactttgat
    61501 ttaaaagaag tagtaaatgg catatgtaaa aaattaattc atagacatcc tcatatattt
    61561 agtggtgcaa aattagatat gtctaagttt gagaaaactt gggaagaatt aaagaaagaa
    61621 gagaaaggcg aaagtactat aacagatggc cttagaagga taccaaaaca tttaccagct
    61681 cttatgaagg ctagtaaagt tcaacataaa gcagcacttg tcggctttga ttgggacaat
    61741 gtagaagatg tatttaaaaa aattgaagaa gaatatcagg aattacttga cgaacacagg
    61801 gtcgggaata taaaatacat aaaggaagag ctaggcgatt tattattttc gatagtaaat
    61861 ctagctagat ttttagacat agactcagga gaagccttga actgtactac agaaaaattc
    61921 ataaatagat ttgactttat agaaaaaagt gcaatgaact tgaataaaaa attagaagac
    61981 atgacacttg aagagatgga tgagttttgg aatcaggcta aaaaacaata aaattgtgga
    62041 aggaaatttg tcaaaaatct agaactttta tcacaaagat agaagtctat attataaaca
    62101 tttttaggag gtaaatatcg tgaataaagc tgaattagta tcaaagatgg cagaaaaaag
    62161 tggattaaca aagaaggaag cagaagctgc gttaaacgca tttatgagtt ctgttcaaga
    62221 tgcactagta aataatgaaa aagttcaatt agttggattt ggaacatttg agacaagaga
    62281 aagagctgct agacaaggaa gaaatccaag agatccagag caagttatag atataccagc
    62341 ttctaaagca ccagttttca aagctggaaa aggattaaag gatataataa atggataatt
    62401 agaaatcttg tgaaaaagtg tggataaatt tgccacactt tttctataga accaaggaag
    62461 gtgataatta tgagattaga taaattttta aaagtatcta ggattataaa aagaagaact
    62521 gttgctaaag atgcatgtga taaagggatt gtcactataa atggaaaagt tgctaaatct
    62581 tcttcagagg tgaatattgg agatacatta gaaatacaat ttggagagaa gaagatgaag
    62641 tttaagataa atgaagtaaa agagcatgta ttaaaaaatg atgcaaaaga aatgtacgaa
    62701 attttagaat aaaattaata gtcctctagt atattaatag tagtattatt gaaatattta
    62761 ctggggggat attatggaac agaacataac tttgaaagat agatcaaagc tggttatttc
    62821 gggagtcgag cacatatact cttttaatga caaaagagta gagctcaaaa cttctgtagg
    62881 cgagatggta attgaaggcg aaaacctaga tatgagcaag ctaagtatag acgaaaatat
    62941 aattagcata gatggaacta taaattctat ggtatatgca aagcctaaaa agccacaaga
    63001 gagtttcttg aaaaaggtat ttagatagat gatacctttt actcaagatg taagcatttt
    63061 ttatgctact atttatggtg gaatactcat aggggtgttg tttgattttt atagagggct
    63121 aagagggaat tttaaattca tcaattattt tgctataatc tttgatgtat tgttttggtt
    63181 tctagctacg gttataatat tcgtaacaat aaaccttaca gaattttttg atttaagata
    63241 ttatcatttt gtggctttgt ttattggttt tattttatac tataacacca taagtaaaat
    63301 tgttttatca attatcaata aaataattcg ttttgtgaga aattctttta aaaaagttac
    63361 acattacata gtcagttttt taaataattt gtattacgtt ataatctatt cactacacct
    63421 actatttgat attatatttt atataccaaa catatttata gcaacaagaa aaagtataaa
    63481 aagaaaatca aataaaaaat taaagaacaa gaaaaaatca aaacctaaga agaaaaaaaa
    63541 taaaactaaa aaaagggtgt aggaaaaatg aacttaagaa aaaaattttc aggacagatt
    63601 attgttatca gtttattttt aggaatatca atttttagta tgatgacagg atttgtattt
    63661 gagtatacaa aagctaagga atataaaaaa gaaatagcaa gtctaaataa acaattaaaa
    63721 aagactgaaa tacaaataaa cagcttaaag aaagatgaaa aatcatatga aggagactta
    63781 gaggatatag caagaaaaag attgaatatg gtaaaaccaa atgaaacagt ttatgtagac
    63841 ataaatcgtt gattaaaact tgctaataag tttacagatg tattgatttt aaaatttaag
    63901 atttaataaa aaagtcattc agttaaggat ggctttttgt ttttattgag gagggaattt
    63961 cataatgaaa gtaggagcta tagatattgg gacaaactca atgagattat tgatagcaga
    64021 ttatagagat gggaatttta taaacagaaa aaaatttgtt aatacaacta gaattggtta
    64081 tggtgtggat agtaaaggat atataaaaga agatgctatc aaaagaaata taaaagcatt
    64141 aaaagaattt tctgataagt gtaatgatga aaagtgtgaa aaaatttatt gtatgggaac
    64201 atctgctctt agagacagta aaaatggaga ttactttgtt aaattagcta aagaagaaac
    64261 tggaatagat gttgatatag ttacgggaat agaagaatca aatttgggct ttaagggtgt
    64321 tttagaagga atacaaggtg atgatactat tattgttata gatattggag gaggttcaac
    64381 agaatttatt gtaggtgatt cagaaggaat tatatttaat aaaagtgaga atgtaggtgc
    64441 tcttaggatg acagagaggt ttttgaagca cgatattatt gaagatgaag agtttgaagc
    64501 tatgagttca tttatatatg gtgagattga caaaacgtta aatcatataa aagacagagg
    64561 attaaaaact cttataggta taggaggtac gattacatca ttatcagcaa tgaatcaaga
    64621 attagagatt tactctatgg aaaaaataca taatagtaaa atacacaaaa aagaaataga
    64681 agaaattcta caaaaattaa taaagatgac attaagtgat aaaaagaact taaaagggct
    64741 acaagaaaaa cgtgcggata ttataactgc tggtgtaaaa atattgaata taataatgga
    64801 aaaattagaa atagaagaaa taaccgtaag tgaatacgat aatttggaag gcttaatatg
    64861 tcaaaagtca aaaaaaatgt attaatattt tttgattttt aaaaccgatt atgacaaaaa
    64921 aaattactcc tctttgttac aattcttaat ataaacaaaa gaggaggttt ttttatgcaa
    64981 agaagtgtag cagttgtgaa gaataagact gtaaaaccaa atgtcataaa attaataagc
    65041 ggatatattg attttactac ggcggcattc gctgtgatgg gatttttact tagtaggtct
    65101 attatagtag actctgtagc tcctttagga attgcctttt ttatatgtgc atcaaagatt
    65161 gataagtaca agatacctgt attcatatca acattattag gaatattgtt atcatctaat
    65221 gattttggaa atgtagcaaa atatgctgtg tgccttacaa tatttatggc tatgaataaa
    65281 aaattaaaat tatcagattc aattgctaag gttgcattta taggtgcaat aatactactt
    65341 ccaatctcca tgggacaagc tttcttttca aataggtatg tatatggtct tcttatagca
    65401 ggagtagaag caataataat gtttatatct atatatgtgt tttcttatgg gataggttta
    65461 atggccaatg tcaacaatag gatgtctgta cggacagaag aagccatatc aataagttta
    65521 ctgctaacct ttagcataat gggaatagga gatatatctc tgtttggaat atcaataagg
    65581 accattttat cgaccgtatt gatattgctg acctcaatag taggtggagc taccatggga
    65641 gcatctagtg gtgtaattat tggtgtagca tccattttaa ataatatgac atcagctgtt
    65701 tatatgggga tatattcttt ttcaggatta ataagtggag catttaataa aataaataaa
    65761 tatttctgta tactaggata tattctaagt tggacaataa tatacctata tacttctggt
    65821 attacttcta atatgatgca attaagagat atactattag gtagtttgat agtactagta
    65881 ttgccagagc gattatttaa taagattgaa aaattaataa aaagtaatgt ggcttcaaat
    65941 gaaatcgtat acgattatat tatgagaagc aaaaacctaa ctaatagcag attgaacagt
    66001 atttataaaa cttatgatga ccttgcagat acatttgata agataagaga aaaagacaaa
    66061 gtgctagacc aaagagacat agctaatgta atagatatga ttcataatga tgaatgtaaa
    66121 agttgtagta tgagaagaat gtgctgggag tcaagattta atcatacata cactatgata
    66181 tataacattc ttgaaaaaat tgaggagaaa ggggagttaa gtctaaacga tatacctaaa
    66241 aattttagaa aggaatgtat gaaaccagag tcaatagtga aaatatcaaa tcactattac
    66301 aaaatgtttg tattagatta tgattggagt gtgaagtttt cagaaagtag aaagttaata
    66361 gcaaatcaga taagaagtat ttcaaaatcc attaaatcct tatctcaaga tttagaaggc
    66421 gacataatgc tagatataga aaaggaaaaa aatatatatg aacagttaga aagatatgat
    66481 ataacagttg ataaagtaag ttacttaaca aaaagtaaca gtgagtttga aatatcaata
    66541 gaaaagaaaa cttgccatga tggatgtatg tgtgaagata aaattgtaaa tataatttca
    66601 gacctagtag gggaaaatat gtctgttaga aaaataggat gtcactgttt aggaggtaaa
    66661 tgcaaggcaa cattcgttaa atctcaaaaa tataaggctg ttacagaagt ttcagcaatg
    66721 tcaagggatg ggcatatcct ttgtggagac aattacacat acatggagat aaatgatggt
    66781 aaatacatga tggctataag tgatggtatg ggaaaaggta aaaaagcata tgaagaatct
    66841 tctgccacta ttgatatact ggaaaaaatg atagatgcaa aaattaaaga tgagatagtc
    66901 attgatacta taaataatat gttgttgtta aagtcttcag aagagatgtt ttcaactctg
    66961 gatttgggaa ttttagattt aaaacgaggt tgtttagaaa ctataaagat gggagcgtgt
    67021 tctacttata taaaaagaga ggatggagaa gttgacttaa tatcgtcatc atcattacct
    67081 gtgggtatat tatcagatgt aaaaattgat agaaaaaatg taaaagttaa ggaaggagac
    67141 tatgttataa tggtttctga tggaattgta gatgcaggaa gaaataacaa tttaggagac
    67201 aattggttaa tatacttctt aaagaatata gagactacaa atccaaagga aatttcaaat
    67261 ttaatattgg atagagcatt agagttacaa gcgttacaaa ttgaagatga catgactgtt
    67321 ttagttacga aaatatgtac aaaataaggt ttacaagatt atgtgtataa gatgtggata
    67381 acttgtgtat aatatgttaa tagacttttg aaaaaagtat agttattaac aaaaataaca
    67441 tataaatcaa caaaatttgt tgataagtat ggcagaaatg ttaataaaat gtaaaaaaag
    67501 aaaaaacaaa agctattatc aaaagagatt catgttgaaa taactaaatt tctaagtaaa
    67561 gaaaacctgt gaatatgttg attattatgt ggataactat taattcgata tttatttata
    67621 tagtatgaat aattgaataa tatatctaaa aaaagccatc ctattattaa gtaaacttat
    67681 tgaaaggatg gctttttatg aatagaaaat tgtgcaaagc aataatacct ttatttattt
    67741 ctattttttg catgttaata ataagtataa aagctgacca aggatatcaa aagaataatg
    67801 acagagcaat tactgtcatg aataataatg atactgaaga tgatgctgaa aaaaaacaag
    67861 aaatagacta tgaaaaaaca tgttggaatt tgcaatcttt gtttaaaagt gatgaccaat
    67921 ggaaaaaaga acttaagagt tttgataaag atactaaaga gttgaaaaat tacataggta
    67981 aagtaacaaa atcgccaaca catttgtctt ttgccttaaa cattaaagaa aaacttgata
    68041 taagactaaa taaactttct gcctatgtaa aattaaaaca agatactaat aaaaattcgt
    68101 ataagtactt agatatgaat gatagtatga gtaaatccta tgggaattat atggggattt
    68161 gttcagattt agagttagaa atactaaaat tatcaaacaa agattacaag aaaattattt
    68221 caaataaaaa tataaatagg aaatatggtg catatttaag agatataaga aggaataaag
    68281 tacattattt ggatgataaa tcagaagata ttctaagcaa agtatcttca ataagtagtc
    68341 ttccaagcca agtgtatgaa ttatttagaa atatggatag aaaaactaat ttgacaccag
    68401 ctcaatatgc gagtgaatta gagtcatcag atagagaaaa tagaaaaaaa gcttatcaag
    68461 atgaacttat aacttacaat gataatataa atacaattgc aggtttaatt actggtcaag
    68521 ttaaaaagaa tattttttat tctcaggaaa gaggttatga gtcttcttta gaaatgtacc
    68581 tggaatctga taatgtagat gaaaaagtat acaataattt gataaggact gtaaatagta
    68641 atatggacag tctacacaaa tatatagatt taagaaaaaa agtattaaaa ttagataagg
    68701 ttcattcata tgatatgttt gtgcctatgg ttaaggctgt tgataataat attaattatg
    68761 aaaaggcaca aagtatagta tattcagcgt tgtcaccttt aggaaaagaa tacaatgatg
    68821 tagtatataa agctttcaat gaaaaatgga tagatgttta ttcacatgaa aataaagtaa
    68881 gtggtggata ctgcttatct gtttatgaaa atcatccata tatactttta aattataata
    68941 attcattagg ttcagtttcg actttatcac atgagcttgg acatgctgta tatgaatatt
    69001 taagttctaa gaatcagaat tattttaatt caaatccgtc tatatttact cacgaagttg
    69061 catctacaac gaatgaagca ttactttacg agatgcttat aaaagaagct aaaggcaatg
    69121 atgaaaaagc ttattatata acacagtatt tagacttgat aaaagatact ctttatacac
    69181 aaactatgta tgctgaattt gaaaaaacta tacacgagtt agtagaaaaa ggaaaaagtg
    69241 taaacgcatt agtattaaat gatgtttggg gacaacttct taaaaaatat tatggacaaa
    69301 gctatgaatt agaccaatta tctaaggtcg gatgggctag aatcccacat ttttataata
    69361 gtttctatgt ctataaatat gctacaggtt gtagtgcagg agtaagtttt gcccaagaca
    69421 tcctaaagaa tggttcagat aactatatga gctttcttaa aaagggaagt tcagattatc
    69481 caataaactt gttaaaatca agtggcataa atttaactaa tacaaaaccc atagaaaata
    69541 caatcaaaaa atttgatagt ttagtagcag aacttgaaaa gctattataa acattattgt
    69601 aatccacatg gtaaatatat cgaattaatg ataaaatata ctaaaagttt aaagtcctat
    69661 caagatagga ctttttattt attaattagt gggagatgat tctatgcaag ttaaagttaa
    69721 aaaggctgta ataccagcag caggtttagg aactagattt ttgccagcta caaaggcaca
    69781 accaaaagag atgttaccaa tagttgataa gccaactcta caatacataa tagaagaagc
    69841 tgtggcctca ggaatagagg aaatactaat aataacaggt agaaataaaa aatctattga
    69901 agaccacttt gataaatctg tagaattgga acttgattta gagaaaaaag gtaagaaaga
    69961 attgttggag gtagtacaaa acatatctaa catgattaac atacattata taagacaaaa
    70021 agagccaaaa gggttgggag atgcaattta ttgtgcgagg cattttatag gtgatgagcc
    70081 gtttgcagta atgttagggg atgatattgt agataatgat gtaccttgtc taaaacaact
    70141 aacagatgca tatgaggaat atagaactac aatattgggt gttcaaaagg taaatcaaga
    70201 agatactaat aaatatggga taatagaagc aaaaaatata gaaggtagag tttacaaggt
    70261 aaaagacatg gtagaaaagc cagagtcagg aaaagctcct tcaaatattg ctattttagg
    70321 tagatatata ataactcctg aaatctttga tattcttaag gatttaccac caggtaaagg
    70381 tggagaggta caacttacag atgctttaaa aatattatct aagaaagaag ctatgtatgc
    70441 atacaatttt gaaggcaaga gatatgatgt tggggacaag ctaggatttt tagaagctac
    70501 tgttgacttt gctctaaaga aagaagacct taaggaagat tttataaaat atttgaaaca
    70561 tgtatgtagt gaatttgata aaaataacaa tgtgttatac aataatacag atgaaaaaat
    70621 agatttaatt gaagtcaatg aagctagaga acttgaaatt caaaaataat taatgaaagg
    70681 tgatgtatgg tggcaaaatc aagtcagaaa aaaattaata gaataatagc tgttgggatt
    70741 gtgggaatcc tcgtaataac gagtataaca gttgttttga gtatgattgc aactatgtaa
    70801 taagataaat gacagcagtt gatatacata aatataaaaa ccatatataa cttgatgtag
    70861 tcaaaaactt acaatatttt agttatatat ggtttttaga atttataaat gtaaaaaaaa
    70921 atttttataa tagttgcata ttttaaagga aaatattatt ataagatata aatatagtga
    70981 taaatttata aaaacgtgct aagattggac ttgaaataca gtaatatagt aggtaataat
    71041 gttttaaatt ttatttattg accataatat ataaataatg atattattag acttaactgt
    71101 ttaaataaaa cttttctttt tcatgccttc aatttccaaa ataagtatgt atataaatga
    71161 atatatagat gaggaggatt tttttgattt tagatgataa agtattagaa ggattaggta
    71221 gtaagacctt agttgagcta cgagagatag ctaaagaatt aaaaataaaa tcaattacta
    71281 catataagaa aaatgagtta attgagatta taaattccaa aagtaaaaat gaggaaaaag
    71341 taaacgaaga gactaaagaa aaaaatgaag atattaaaga agacataaag aatagaaaag
    71401 aaaatataga gcgtgaaagt atagaaaaag aagttgaata taagagccct accaaatcat
    71461 acaacaagaa agaaatagat acccaaaata tttcccaaaa ccaagaacat agaaatcaaa
    71521 gaaatgacta taataagaca acgagtgtaa atgatagcaa taagtcatca aatatatcta
    71581 atagaatggt cagaaataat aataaaaact attatatgcc taaacaagtt gatgaatcta
    71641 agatagtaga tgaatttaac acatcaaaag aggatgaagt agtaggtgta cttgaaattc
    71701 tgccagatgg atttggtttt ttaagaggtt caaattattt gtctactgaa ggagatgttt
    71761 acgtttcacc atctcaaata agaagattta atatgaaaac aggagacaag attaagggaa
    71821 taactagaca tccaaaaagt ggagagaaat ttagagcact tttatatgtt caaaaaataa
    71881 atgatgaaaa ccctgacaca gctatacaaa gaaatgcgtt tgagacatta acaccaatat
    71941 ttccagaaga acgacttaca ctggaaacta atagaaatga aatagctaca agaattatag
    72001 atttaatttc acctatagga aaaggacaaa gaggattgat agtagcacct ccaaaagctg
    72061 ggaaaacagt tcttttaaaa agcgttgcaa atagcatagc taaaaatcat ccaaatgttg
    72121 aacttatagt actccttata gatgaaagac cagaggaagt tactgatatg aaagaatcta
    72181 ttgaaggaga cgttatatat tctacttttg accaagtatc aagtcatcat gtcaaggttg
    72241 cagagatggt gttaaataga gctcaaagat tagttgaaca tggtaaagat gtagtaattt
    72301 tactagatag tataactaga ttggcaaggg catataacct tacaatatct cctacaggta
    72361 gaactttatc tggaggtatt gaccctggtg cacttcatgg acctaaaaag ttctttggtg
    72421 cagcaaggaa tattagacag ggtggttctt tgacaatatt aggaacagca ttggttgaaa
    72481 ctggttctag gatggatgat gtaatatttg aggaatttaa aggtacagga aatatggagc
    72541 tacatttaga tagaaaatta gcagaaaaaa gaatattccc tgcaatagat atttacaagt
    72601 ctggtacaag aagagatgat ttattgcttg atgatgaaga aaagactgct ctttggagat
    72661 taagaagaga aatgagtaat aattcagtaa tggaaattac agataaagtc attgaactta
    72721 taaagagaac taaggacaat aaagagtttg taaaatcaat aaagaatttg taaaatcaat
    72781 aatacaaatg caaatatgga ttatataaac taatagaaaa atcacttgaa tggcataata
    72841 agttgtgcta taataatgta gttgataatg taaaaagaaa gttaatataa ttaatttttt
    72901 taaataaaga gaagaggtga ctataatgca aaaggaaata caaccaaaat acaatccagt
    72961 tgaagtgcgt tgtgcttgtg ggaacacatt tgttgctggt tcaactaagg acgaaataaa
    73021 agttgaaata tgttcagagt gccatccatt ctatacagga aaacaaaaga acatagaaaa
    73081 aggtggaaga atcgacaaat tcaagaaaag attcaaaatg gactaatttt tataaaagtg
    73141 gagttggagg aagccaactc ctattttatt acaaaaaaac attcatattc tactttaaat
    73201 tgtctttttg tattataata ataaatatgt aaaattgagt attctaaata caataaaatg
    73261 aggtgagtgg atggcaaaac aagctgtagg tgggcaagct gttattgaag gtgtaatgat
    73321 gcagtcaaaa gacaaaagag cggtagctgt tagaaaaagt gacggagaaa tagcactaaa
    73381 agaagataga ataaaaagtt gggtaagaga taagaatata gataagatac cttttgttag
    73441 aggttctttt gttatgatag atacaatgat tcaaggcata aaaagcttaa acttttcttc
    73501 agagtttttt atggaagaag ctgaagagga taaatttgat ttatttataa agaaaatttt
    73561 taaagataag gcaaatgata taattataat attttcattg gtcatagcaa tgttactttc
    73621 tgctggatta ttcattttta tacctacatt ggtaggagga gctttttcta aagtaatgcc
    73681 taatgatttt atgcttaatt taatagaagg aatcataagg atagctatat tatttgcata
    73741 tatagtattg atttcacgaa gtaaggatat agaaagagtc tttcaatatc atggagcaga
    73801 acataaatct atatattgct atgaaaatga tttagaactt acagtagaga atgctagaaa
    73861 atttaaaaga ttacatccta gatgtggtac gaatttccta tttatagtta tggctgtatc
    73921 aataatattg tttgcatttt ttggttggcc aaatccaatt cttagaatat ttatgagaat
    73981 tatatgtgtg cctatagtag caggtttatc ttatgaggta attagagttc ttgggaaata
    74041 tgataatgga tttactaaaa ttattgcata tccaggaatg atgttgcaat attttacaac
    74101 aaaagagcct gatgatgagc aattagaggt tgctttggaa gcattgaaag cagtagtaga
    74161 ttagagaaaa ggatatttgt tatgacgata aaagatataa ttattaaata ttcagataaa
    74221 ctaaaagata taagtgatac tccaagatta gatacagagt tattgttaca aaaaacattg
    74281 ggtgttgata gattatatat tcacttaaat ctgaataaag agctaactga agaacaaaaa
    74341 acaaaattta tgggttttgc agaagaaaga ttaaatggaa gaccaatagc atatatagtt
    74401 gaaaataggg agtttatggg attagatttt tttgttaagg aaggcgtatt gattccaaga
    74461 ccagatacag aaactttagt agaagaaata attgaaatat gtagagaaaa aaaagatgta
    74521 agtatattag atataggaac tggttctgga gctattacaa taagtttagc aaagtacatt
    74581 gaaaattcta aaatcatgtc ttttgatata tcagagacag cattagaaat agctaaaaaa
    74641 aatgctatta taaatgaagt tggtgaaaaa ataaagtata ttaattctga tttatttaca
    74701 gcaataagtg atagtaacat aaaattcgat atcatagttt caaatccacc atatattaaa
    74761 aaacaagata tagaaactct gcacaaacaa gttaaagatt atgaaccata taatgctctt
    74821 gaaggtggag aagatggatt agacttttat agaagaataa cagaacaagg taagaaatat
    74881 ttaaataagt gtggaatatt agcatatgaa gttggtcata atcaagctga agatgtaata
    74941 aatattatga aaagtaatgg atataaaaaa atatatacaa agaaggatat tcaaggcatt
    75001 gatagagttg ttataggtta caatatatga tataatcaac aattgatatg ttacatttaa
    75061 tcgaggtgaa agtatgttaa aaaaattaga ggtattggaa gatacatata aagacttaag
    75121 tgaaaaaata ggtgatccgg atgtaataaa tgatcaaaaa gtttggcaga aatatataaa
    75181 agaacatgct gacttggaac ctattgttat gaaatacaga gagtataaaa gcgttttaga
    75241 tagtataaaa gaatcaaaag aaattttaca agaagagtca gatgaagaat taagagaatt
    75301 agctaaaatg gagttagctg agatggaaga aaaagtagca cctctggagg aagaaataaa
    75361 aatactatta ttgcctaaag accctaatga tgataagaac gttatagttg aaattagagg
    75421 tggagctgga ggagatgaag cagctctatt tgcgggtgat ttatttagaa tgtactcaag
    75481 gtatgctgaa agaagaagat ggaaaataga attattgagt gcaagtgata ctggagttgg
    75541 tggatataaa gaagtatctt ttatgataaa aggtaaaggt gcttattcaa gattaaagta
    75601 tgaatctgga gttcatagag ttcaaagaat accatcaact gaatctggtg gaagaataca
    75661 cacatcaact tctactgttg cagtattacc agaagttgaa gatgtagagg ttgaaataaa
    75721 tccaaatgat ttaagaatag atgttttccg ttcttcgggt aatggaggac aaagtgtcaa
    75781 tactactgac tctgctgtta gggtaacaca tatacctaca ggtgaagtag tatcttgtca
    75841 agatggaaaa tcacaattaa aaaataaaga gcaagcttta aaaatattaa aagctagact
    75901 ttacgataaa gcattggcag aacaacacaa agatatagca gcagaaagaa aaagccaagt
    75961 cggaacagga gacaggtcag aaagaataag aacatataat ttccctcaag gtagaataag
    76021 tgaccataga ataaatttaa ctttatataa gctagatgca ttcttagatg gagatataga
    76081 tgaaatgata gatgctttaa ttactgttga ccaaacagaa aaaatgactg caatataagt
    76141 aatgttttaa agaagctgtt tcttcctaga aattattttc tattttgaaa cagctatttt
    76201 gcattttagg tcatgttatc atattctatt gtatataatt gttatataca agtataggag
    76261 ggttatatga tactaaaagt aacaataatt gggcttttgg caggtgttat agggacagga
    76321 ttaggaggag taatatcagc catttttaaa agagaggtcg ataaatatct aagttttttt
    76381 atgggattat ctggtggaat aatgttggct gtagtggtgt ttgatttaat gaaagaatcc
    76441 atggacaaaa tggggataat caatacagtt atatttacgt ttgttggagc tctcataact
    76501 atgtacataa aaacaaaatt agatgtgtct ggaaatatgg catctggata tcttatattc
    76561 ataagtatat tactacataa tttaccagaa ggactagcca ttggttcttc ttttatgtca
    76621 actgaaagtt taggtattac acttgctata gttataggtc tacataatat accagaaggg
    76681 ttagctatgg cattaggctt agtttgcaat aaaatgaaac taagtaaagt tattttgttt
    76741 actgtaatag ctggattacc tatgggtcta ggaagttttt taggtgttta ttttggagga
    76801 gtatttactt ctcttatagg agtatttctt gctacagcag gaggtactat gatgtatgtt
    76861 gtattggaag aaatttttcc acattcaaaa agtgtgtatt gtataattgg tttcttgtta
    76921 ggtacaatga ttgtaaatta tatataaaat taaaatgaaa gcaggcatac aaaagatgaa
    76981 aactattata agtaatattg atataaataa tattgattat gaggaaataa aaatacaagc
    77041 aaaacttctt agagaaggta aaacagttat ttttccaact gagacagtat atgggttggg
    77101 tgcaaatgca ttagatgaaa atgcagtaaa gaagatttat gaagctaaag gaagacctag
    77161 tgacaatcca ttgatagtcc atatatatga aaaagaagaa gtatatgact tagccaaaga
    77221 tataagtgat aaagctaaac ttgttataga aaagctttgg ccaggaccta taacaattat
    77281 attaaataaa aaagatataa ttccatacaa aactagtgga gggcttgata cagttgcaat
    77341 aaggatgcct tctaatgtta ttgccagggc aataataaaa gaagctggta tacctattgc
    77401 agctccttct gcaaatatct caggtcgccc atctccaaca aaagcaaaac atgtatatga
    77461 agagatgaat ggaagagtgg atggaatagt tttaggagga gacagtaatt ttggattgga
    77521 gtcaactgta ttggatttaa cagaagagac tcctatgata ctgagaccag gaagtataac
    77581 taaagaagtt ttagaggaac ttcttggaga ggtaaagctt gacccatcat taagtaaaaa
    77641 agaagataat caaaaagcta aagctcctgg aatgaaatat aaacattatt ctccaaatgc
    77701 agatgtatat ataatatctg gaaaaagaga aaatgtagca acaaagatta atgatatgat
    77761 aaaatctaat agagacaaag gtctaaagac aggtgtaatg tgtattagta gaaaccgaga
    77821 gttttatgat ggagaagtaa tcgatttagg aaactctctt gaagaagttg caagtaatct
    77881 gtttgatgct cttatagaaa tggacaaaaa gggtgttgat gtcatatatt cagaagagtt
    77941 ccctaagact ggagttggac aagcaattat gaatagacta ctgaagtcag caggatacaa
    78001 agtgataaag gcttaagagg gagttgtaaa atatgaatat acttattgtg tgtacaggta
    78061 atacttgtag aagtcctatg gctgaggcta tactaaggaa agcaattaaa gaatctggaa
    78121 gaagtattga agaatattct atatcatcag caggtatatc tacagcaaat ggaatgggtg
    78181 cttctgaaaa ttctatagaa gtactaaaag aaatcggtat agacttatca aatcatagaa
    78241 gtaaagtaat tactaaaaaa ttaattgatg aatcagatat aatactaaca atgactaaat
    78301 ctcataaaga aattttagta caagcagttc caaaatgcaa agaaaaagtg tatactttta
    78361 aagggtttgc aaataaaaat gaggaagata tatctgaccc atttggtgga aatttggata
    78421 tttatagaag cactatgaga gaaataatgt attctgtcaa cgaaatagta aaaaaaatat
    78481 gaaacggagg ataaacaaat gaagatagga ttaggctgtg accatggagg atataattta
    78541 aaaaaagaaa taataagcta tttagaaagt aaaggtatag aatgtgtaga ttatggaact
    78601 aataatgcta cagattctgt tgattatcct gtttatggag aaatagttgc aaattcagtt
    78661 ataaataaag aagtagatta tggaatatta tgttgtggta cagggatagg aatatcttta
    78721 gctgctaata aggttcctgg gataagatgt gcagttgtat cagatgtatt ttctgcaaaa
    78781 atgtcaaaag cacataatga tgcaaatatg ttatcattag gcgaaagagt tttaggaaaa
    78841 ggtctagcac ttgagatagt tgaagcatgg attaatacgg attttgaagg tgatagacat
    78901 gctagaagag taaacatgat taaatcaata gaagaaaaac ataataaata ataaaaatta
    78961 cagttttatc aggaggaatt atcaaaatga gcaaagtggt agagacaaac catccattaa
    79021 tacaacataa attaacttta atgagagata aaaatactgg ttctaaagac tttagagagc
    79081 ttttaactga aattgcaatg ttaatggggt atgaaataac aaaagatata ccattaaaag
    79141 atgtagaaat agaaactcct attcaaaaaa catcatctaa agtagttgca ggtaaaaaat
    79201 tagcaataat tccaatttta agagcaggtc ttggaatggt agatggatta gtgagcttaa
    79261 tgccagcagc aaaagttgga catgtaggac tatatagaga cccagaaaca ttaaaaccag
    79321 ttgaatatta ttgtaagctt cctcaagaca taggagaaag agatataata gtagttgacc
    79381 ctatgcttgc aacagggggt tctgctgtag cagctataga tttacttaag tctaaaggag
    79441 ctaaaagtat aaaattagct aatttagtag ctgcaccaga aggtatagca gaagtgcaaa
    79501 aatatcatga tgatgttgat atatatgttg catcagttga cgaaagatta aatgaacatg
    79561 gatatataat tcctggtctt ggtgatgctg gagatagatt gtttggaact aaataaaaat
    79621 aaataactat aaatatttat tagggacttt cttatatagt gtatataatt ttatgtaaga
    79681 aggttctttt ttatatattt tttctcaaaa taggaattat tgaattgata aatttctcga
    79741 attgagaata aaaagttttt accaattaaa aaagattgct tattttacaa ggttttatag
    79801 aatagtagtc tattttaatg tggcatgtta gttgcttacg attataggta ttaagtgtat
    79861 tagttaaatt gagaattgaa tattaataat attattggga gtggtaatac atgaagaatt
    79921 gtatagtagt aagaggggct ggagatttag caacagcagt tattcataaa ttacacaaca
    79981 gtggttttaa agtagttgcg ttagaaatag aagagccatt agctataaga aggcaaattt
    80041 ctttttgtga ggctgtttat gaaaaaaaag taactgttga aggtgtagaa tgtatatttt
    80101 gcaatactga aaaagaaata gaggaagttt tatctcaaca taaagtagcc ttgattatag
    80161 acccaaaagg agaaaaatta tctaaattaa atccaatcgt tttggttgat ggaatactcg
    80221 ctaagaaaaa cttaggtaca actaaagata tggcaccact tacaatagct ttaggtcctg
    80281 gattttgtgc aggagaagat gtagatgttg ttatagagac aatgagaggt cataatctag
    80341 gaagaataat aactaatggt agagcagaaa aaaatacagg agtaccagga gcaataaaag
    80401 gtttttctaa agagagagtt atgcattcac agtatgatgg cataatggaa aatgtatgta
    80461 agataggtga tatagttgaa aagggagacc tactttgcta tattaataat tatgaaaaaa
    80521 aacatgaagt tagagcaaca atatctggag tccttagagg tttattaaag gatggagcaa
    80581 aggtaaacaa aaatttaaaa atactagaca tagaccctag aaaagaagaa gttaagaatg
    80641 cttttacaat atcagataaa gctagatgta tagctggagg ggttttagaa gccatactaa
    80701 acaatgggat ttatccccaa aattaattta tattagataa agctattaat attttattaa
    80761 gatgatataa taaatttaat agattaaaga gagcatatga cgggtattta aaatttaaat
    80821 ggtaaaaatg ctcttttttt attggacatt caattaacat gtgtatataa tataaaaata
    80881 agtatttatt taggttgaaa tctaataaat atataatacc agtacataag caaagaggag
    80941 aaaagtaaat tatgagacca tcatgggatg aatacttcat ggaaattgca gaagtagtga
    81001 aaaagcgttc aacttgtatt agaagacaag taggagctgt aattgtaaga gacaaacaaa
    81061 tattaacaac tggatataat ggttctccga gaaatcttga acactgtgaa aatattggat
    81121 gtaagaggca ggaattaaat attccctcag gagaaaggca tgaattatgc agagcattac
    81181 atgctgaaca aaatgcgata atacaagctg ctcataatgg tattagtgta gatggggcaa
    81241 ctttgtatgt tactacaaga ccttgtgttt tgtgtgcaaa aatgtgcata aatgcaggta
    81301 tattgaaaat tgtttatgaa ggtgattatc cagatgatat gtctacagaa ttattaaaag
    81361 aagcaggaat agaactcata aaattttagt ggataaaatt tataagacaa taaatgtcaa
    81421 attatgacac tgaaatacaa tggtatcaaa tgattaaaag aaagtatttg aaaaatcatc
    81481 agattagtag taagatatat tttataatta aataaattta tgagatagat taattacatg
    81541 ttatttattt tataataatg agggatacta tttatgagta aaagaaatac acatacagaa
    81601 attgcaaagt tgtttagttt aataagtcaa ataggattga tgattgtaat atcaatatta
    81661 ggatgtactt tcttaggaaa atttttagat agtaaattga atactactcc agttctgaca
    81721 ataatatttt tattgttggg tgttggaggt gcttttagtg gtgtttataa aactctaata
    81781 gtatatacac gaaggaagtg atatattgga tataaaatta cttaaccagg taaggtcagt
    81841 aacaaaaggt atagtaatat ttgatgtagt tttaattgtg ctaatgttga taacatcaac
    81901 attaagtaaa ccagtattat taggacttat atttggctct ataatagcta tgttaaattt
    81961 tagattattg gcgatatcac tggaaaaatc agtgacattt cctgctggga aggcacaagc
    82021 ttatgcatca gcacaatatg ctgttagatt atttataatg gcagttgttc taattgcatc
    82081 agctacagta ccacatttaa atataatcgg aacagcattg ggattattga gcacaaagtt
    82141 tgtcatatta tcaaaaaact ttataaataa attaaagagg aaggaggcat aagtatgaat
    82201 caagcgcatt attatctcat aggaaacttt aagattagtg aaacaatact agtaagttgg
    82261 ggaataatgg cctttttagc gatagcatct tattttttga ctagaaactt aaaaaaagtt
    82321 ccaactagta aagttcaaat attcttagaa tttgcagtag gtggtcttgc taaaatggtt
    82381 acagatgtta tgggtaaaaa tacagtaaaa agaatgccat atatgatacc atacatagga
    82441 agcttgtttt tatttttcgc atgttcaaat ttaagcccat tacttggatt aaggtcacca
    82501 acaaccgact tagacacaac tgctgcatgg gcaatgatta cattttttat gatttatttt
    82561 gcaggagtta aatttaaggg gttatcatac tttaaagaat tggctcaacc acttgccata
    82621 atgttaccaa tcaatattat aggtgagtta gctagaccaa tatcattaag tttccgtcca
    82681 tttgggaata ttttaggtgg aacaataata atgggtctgt tttatcaact tttaggtttt
    82741 atatctagtt taataccagg attatcaata ccaattggag aaatattaat accagtccca
    82801 ttacacttgt actttgactt atttgcagga ttgttacaag catatatatt tataatgtta
    82861 acaatggtat ttatatcaag tgcaggagag ttagattaag aaatcaactt atattaagat
    82921 aaaaataaaa taatttaaaa aattaaagtt ttaaggagga aataattatg gaaacagcaa
    82981 tagtagcggc agcatcagca ataggagcag ggatagcagt tgcaacaggt ataggtgcag
    83041 gtataggtca aggtatagca gcagctaaag ctgcagaagc agtaggaaac cagccagaag
    83101 ctaaaggtga tataacatca actttattac taggagttgc tatagcagag tcttcagcaa
    83161 tatatggttt ggttatatca ataatacttc tattcgtaaa tccattcttt aaatacttag
    83221 gaatgtagat ttagtcctta aatattttga gataggttta taggtaaatc atctcaaact
    83281 tataatcatg agatgaactt tatcatctcg tgattataag tagttatgat ttatggaaag
    83341 gaggataatt atggaaaaag cactagtagg tataacgtgg gaatttgtgt tccaaattgt
    83401 taatactttt ataatatttt tacttctgag aaagctttta ttcaagccag tattaaatat
    83461 aattgaatca agagaaaatg atattaaaag tgatttggca gaaggcgaaa aagcaaaaaa
    83521 tgaaggttta gctctgaaaa aagaatatga gtcaaaaatc aattttgcca aagatgaagg
    83581 tcaagaaatc ataaaacaag caactataag agcagagcag aaatcagatg atatagtaaa
    83641 tactgcaaag aaagatgctc ttgatataaa agaaaaagca aacaaagata tagaacaaga
    83701 aagacaaaag gttataaatg aaatcaaaaa tgatatatct aacatagcac tacttgcagc
    83761 atctaaagtt attgaaaaag atttagataa atctaaacat gaagaattga tagaaaactt
    83821 tataaaagag gtaggggaag ctaaatgata aatgtaatag caaatagata tgccgaagcc
    83881 ctatttcaat taggagaaga agaaaattca actgatgtct tattcaaaga actagaaaaa
    83941 gtagtagata tgatgactaa agttagtaaa gatttctaca aagttttaaa atcaccatta
    84001 gtttcaaaat cagaaaagaa aaacttggta gaaattattt ttagtaagga agtaagttct
    84061 aacataaaaa actttttaaa agttttagta gataaagata gaatatcata tttagaagat
    84121 atcgaattag cttataaaga attattaaat aagaaaaaca atgtaattga tggagtagca
    84181 ataagtgcta ttccaatgag tgaaacagat attaaagaac ttgaagtcaa actttcaaat
    84241 aaatacaaca aaaatgttac tatagaaaat gttgttgaca agactatact agggggagtt
    84301 ctagttagaa ttggaaatga acaaatagat ggcactgtga aaactcgtct tgataagatg
    84361 aaagaaaagc tatctgaagt aatatcttaa gaatggcggt gaacccatga acttaaaacc
    84421 tgaagaaata agttctataa ttaaacagca aataaaaaat tatgagaata aagttgagtt
    84481 gacagataca ggtagtgttt taacagttgg ggatggtata gcgagtgtat atggattaga
    84541 aaaagctatg tctggtgagt tgctagagtt cccaggtgaa atatatggta tggcacttaa
    84601 cttggaagaa gaagtagttg gagctgttat ccttggagat gacagtgaaa taaaagaagg
    84661 cgatatagtt aagagaactg gaagaatagt tgaagttcca gttggagaag ctttaatagg
    84721 tagagttgta aactcactag gtcagccaat agatggaaaa ggacctatag cgtacacaaa
    84781 aactagacca gttgaatctg aggcacctgg tataatagat agaaggtctg tttatgaacc
    84841 attacaaaca ggaatcaaat caatagattc aatgatacca attggtagag gtcaaagaga
    84901 gttaataata ggtgacagac aaactggtaa aacatctata gttattgaca ctatactaaa
    84961 tcaaaaagga aaagatgtta tctgtatata tgtagcaatt ggacaaaaac gttctactat
    85021 agctcaatta gttagctctt tagaaaaagg tggagctttg gattatacaa tagtagtttc
    85081 agcaacagca tctgaatcag caccacttca atatatagca ccatatgctg gagcagctat
    85141 gggtgaagaa tttatgtaca atgggaaaca tgtacttata gtgtatgatg atttaagtaa
    85201 acaagctgtt gcatatagag aaatgtcatt gttacttcga agaccaccag gacgtgaggc
    85261 atatcctgga gatgtattct atttacattc aagattactt gaaagagcag ctaagttatc
    85321 tgatgaattg ggtggaggtt caatgactgc cttgcctata atagaaactc aagctggtga
    85381 cgtttctgca tatataccaa caaatgttat atctataaca gatggtcaaa tatacttaca
    85441 accagagtta ttctattcag gtgtaagacc agcagttgac cctggtatat cagtatcaag
    85501 ggttggtggt tctgcgcaaa ttaaagcaat gaaaaaagtt gcaggaacat taaaacttgc
    85561 atattcacaa tatagagaac ttgcagcatt ctcacagttt ggttctgact tagatgaaga
    85621 tactaaaaag agacttgctc aaggtgaaag aatcgttgag atattaaaac aaggtgagca
    85681 tcaaccaata aaagttgaaa atcaagttat gataatatat gctgttataa ataatcattt
    85741 agaggatatt ccgatagata atatagctag atttgaatca gaattgtatg catttgtaga
    85801 taataattat ccggaaatat caagaaaaat attaggtgga gaagacttca ctcatgattt
    85861 aacagatgca ataaatgaat ttaaagaaaa gtttgttgtt gaagtataat cctttttaaa
    85921 aaaggaggta aattaattgg caggagctgg aatcaaagca atcaaaacac gtatgggaac
    85981 tgttgaaagt acaaagcaaa taactaaagc aatggaatta gttgcatctt ctaagcttag
    86041 aaaagcaaaa gaaaaggctg aagattcaag agaatatttt aatactttat acaatacagt
    86101 aaaagatatt gcccaaacaa cacgtggaat tagaaatgaa tttttaaaag aaagagaagt
    86161 aaaaaataaa tgctatgtag tagtagctgg agacagagga cttgcaggtg gatacaattc
    86221 taatgtatta aaggaatctg tctctcatat gaaaggtaaa aaggaaacag tgattactgt
    86281 tggaaagaaa gcacatgaat ttttttctaa aagaaactac aatatagcaa aagatataaa
    86341 tagtgttgaa gcttgtggat atgaagatgc gacagaaatt tcacaaacta ttattgacct
    86401 gtataaaaaa ggtgaagtag atgaagttta tattgcttat acaaaattta aatctgcttt
    86461 atcacaagaa gttgaaattt tgaaattgct tccattagtc tttgaaaaag atacagacga
    86521 acaaggaatg gcagtaaaag aagaaaaaca aaatagatca aaagtacaat atataccatc
    86581 agcagaagca gttttaagtt atattgtacc tcagtttata tcaggtacag tatatggtgg
    86641 aattttggaa tcttttgcat cagagcaagg tgctagaaga actgcaatgg aatcagccac
    86701 agacaatgcg aatgaaatgc tatctaattt agagttaagt tataacagag caagacagtc
    86761 agctgtaact caagaaataa cagagatagt tggtggagtt gaagctctaa aatagggagg
    86821 ttaggaaatg gcaaatgtag gtaaagtagt acagattgta ggagctgtac tagatgttaa
    86881 gtttgatagt gaacaaagcc tacctaactt attaaatgcg ttagtaataa agttaggaga
    86941 taaagaaata gttgcagaag ttgctcaaca tataggtgat gatactgtaa gatgtatagc
    87001 tatgagtgca acagacggac ttgtaagagg tatggaagtt gtagatacag gagggccaat
    87061 aagtgttcct gttggagatg aaactttagg tagaatattc aatgttcttg gaaaaccagt
    87121 tgatgggaaa ccagctccaa aatctgcacc taaattacct atacatagac cagcaccggc
    87181 gtatgatgaa ctagaaacta cagcagagat actagaaact ggtattaagg tagttgactt
    87241 actagctcca tatctaaaag gtggaaaaat aggtctattt ggaggagcag gagtaggaaa
    87301 gacagttcta atacaagagc ttataaacaa tattgctaag caacatggtg gtatttctgt
    87361 attttcagga gtaggagaaa gaacaagaga aggtaacgac ctttatggcg aaatgagtga
    87421 gtctggagtt ataaataaaa cagctctagt atttggtcaa atgaatgaac cacctggagc
    87481 gagaatgaga gttgctttaa ctggacttac aatggcagaa cattttagag atgagcaagg
    87541 acaagacgtt ttacttttcg ttgataatat attccgtttc acacaagctg gttcagaagt
    87601 ttcagcactt ctaggacgta tgccatcagc tgttggttat cagccaacat tagctactga
    87661 aatgggtgca cttcaagaga gaataacatc aactaagaaa ggttcaataa catctgttca
    87721 agcagtatat gtaccagcag atgacttaac tgacccagca ccagctacaa cattctctca
    87781 cttagatgca aaaacagttt tatcaagaca aatatcatca ctgggtatat atccagcagt
    87841 tgaccctctt gaatctacat caaggattct tgaccctagt atagtaggaa aagaacatta
    87901 tgaagtagct agaggtgtac aatcaatact tcaaagatat aaagaacttc aagatataat
    87961 tgctatactt ggtatggatg aattatctga tgaagataag ttaatagttg cacgtgctag
    88021 aaagatacaa agattcttat ctcaatcatt cacagttgct gagcaattta caggaaatcc
    88081 aggtcaatat gtacctgtta aagagactgt aagaggattt aaagaaattc ttgaagggaa
    88141 acatgatgac ttaccagagt cagcattctt atttgtagga acaatagaag acgctgttag
    88201 aaaagcgaag ggaagtatgt agtcatggcc agtgaatttt cattgaaagt tgtaactcca
    88261 agtaatactt tttatgatgg agatgttgaa atgatagtag ttagaactac aaaaggagac
    88321 aaaggggtgt tgaaaggtca tataccattt gtttcaggta tacctgtagg aactttaaag
    88381 ataaaaaaag agggaagttt taaagaggcg aaaatagcag aaggattcat taatgtaact
    88441 caagataaaa ctgtcatatt gacagaatct gctgagtgga tttaataaat taatttagag
    88501 tataaaaagt cattttgacc aaaaaaactt ttgggtaaaa tggctttttt gcgttttggt
    88561 gttaataaaa taacgataaa attgtaagtt tttagtgaca ataaattcac aaaatgttta
    88621 aatttactgc caaattatgt tgtaattaat aagataaaga agatttagat agcttttatg
    88681 taagtgaaaa agtcttcata taagaaatac atataaaatt tttataaaat ttaaaaaatt
    88741 tgcttagttg tgtagtataa taaataatat aatagatttg tatataatat tcattacaaa
    88801 taattttaaa agttacagtt ttattataat gattattaaa ttaagataag taacataaac
    88861 taaataataa tgtgtattat cgatagtaaa tttataaatt cattattaat tattgaaaga
    88921 agtattataa attttctgga ggaacaatga atatatttga tattggcgta gatataattg
    88981 aaattgatag aataagaaag gctgtagaca aaaataatag gtttttggag aagatattta
    89041 cagatagaga aatagagtat tttaattcta agaattttaa agcagaaagt atagcaggta
    89101 atttcgcagc caaggaagct ataagtaaat ctataggtac aggaattaga gtgtttaatt
    89161 ttaaagatat agaagttctc agagatgaaa tgggaaaacc aatagtaaaa acttataata
    89221 atctagcaaa aatgtgcata gattataatg ttttagaaat aaaagtttca atatcacatt
    89281 caaaagatta tgctatagca aatgcgataa ccataattaa ggactaagga gtgattacat
    89341 tatgatggat aaaacagcaa aagaaataat gacaacagat gtaatagtag caaaacaaga
    89401 tgatagtata gcagatgtag ctaatatgct aattgcagaa aaaataggag gtctgccagt
    89461 tgtagattca gagaatagag ttgttggaat aatttctgaa acagatattc ttaaaaaaga
    89521 aaaatatata gaagcacctc tctatataaa tctattacaa ggattgattt tcttagatga
    89581 cttaaaaaaa gttgaaaaag atataaaaca agtagctgct tataaggttg gagaacttat
    89641 gtctaaagat ataataaagg ttcatgaaga tgataagttt gatgatgtag ctaatgtaat
    89701 gattaaaaaa tcaataaaca gagttcctgt agtagatgat gataacaaac ttaaaggtat
    89761 aatttgtaga tatgatataa taaaagcttt atacaatgaa taaactgaag taggaggtgt
    89821 gatgtgagaa aaaagtggac catagtatgt attatgttct tggcactggt tataattgta
    89881 ataggatgcc aaaaacgaca gtccacaaaa gaagaagtat acaaagattt tcaaaagcag
    89941 atttctgata tgaattatta cagttgtaaa gctgaagtag aagtagttgg aaataaaagt
    90001 ccacacaatt atgttttaat tcatacttat aaaaaaaccg ataactataa attagaagta
    90061 atttccccaa aacatttaaa agggaaaagt atagaatatc aaggtgataa aatattagtt
    90121 aaaaatccaa agattagtga tgtagtggag ttacctaata caggaaaaaa taatcaatat
    90181 ctttttgtag gagactttat aaaaaattat cttcaaaatg aggagatgaa agtaaagtta
    90241 tccaaaggac atttggtttt agagactttt attcctgggg ataataaata ttttaacaag
    90301 caagtattat atgtaaatgc tgacacaaaa aatcctgaaa aaatggaagt gttagataaa
    90361 gagggagtgc caagatttac agtaaaatac aaagattttg aatacagaaa ctaaggggga
    90421 ctaaagacat gcaaaaaata acagtgccta catgggcaga gataaatcta gataacttaa
    90481 gatttaactt aaataatatt aaaaatttat tagaagaaga tattaagatt tgtggagtaa
    90541 taaaagctga tgcatatgga catggtgcag tagaagttgc aaaattgcta gaaaaagaaa
    90601 aagtagatta cttagcagta gcaagaactg ctgaaggaat tgaacttaga caaaatggca
    90661 taacacttcc tattttgaac ttgggatata ctccagacga agcttttgaa gattctataa
    90721 aaaataaaat aactatgaca gtttattctt tagaaacagc acaaaagata aatgaaattg
    90781 caaaatcttt aggagaaaaa gcctgtgttc atgttaaaat agactcaggg atgactagaa
    90841 taggtttcca acctaatgag gagtcagtac aggaaataat agaattaaat aaattagaat
    90901 atatagattt agaaggtatg tttactcatt ttgctacagc tgatgaagta agtaaagagt
    90961 acacttataa acaagctaat aattataaat ttatgtctga taaattagat gaggctggtg
    91021 taaaaatagc tataaaacat gtatcaaaca gtgcagctat tatggattgc cctgatttaa
    91081 gattaaatat ggtaagagca ggaataatat tatatggtca ttatccatct gatgatgtat
    91141 ttaaagatag attagaatta agaccagcca tgaaattaaa atcaaaaatc ggacatataa
    91201 aacaagttga accaggtgta ggaataagtt atggactaaa atacacaact acaggcaaag
    91261 aaacaatagc tacagttcca ataggatacg cagatggatt tactagaatc caaaaaaatc
    91321 caaaggttct tattaaggga gaagtgtttg atgtagttgg tagaatatgt atggatcaaa
    91381 taatggttag aattgacaaa gatatagaca taaaagttgg agatgaggtt atactatttg
    91441 gagaaggcga agttacagct gagcgtatag ctaaagactt aggaactata aactatgaag
    91501 tgttatgtat gatatcaaga agagttgacc gtgtttatat ggaaaataat gagcttgtac
    91561 aaataaacag ttatttgcta aaataaaacc atgatattat aatctgggag gcgattttgt
    91621 gtacgataag agtaaagaaa aaatagaagt tactttacct gactctctga tttctgaagt
    91681 tgatagtata gttcagatgg agaacagtaa cagagaagat tttgcaaaag ctgcttttca
    91741 gttctatata actcagaaaa agaaaattca tattaaagaa tctatgaaaa cgggttatag
    91801 agaaatgggt caaattaatc tgtcactagc tgaattaggt atgacagttg aagaagtatc
    91861 ttctgatgat aaaaatgaag ggaagattgc ccaaggtgag tactaattgt gaaataaagc
    91921 gtggtgattt atattacgct gatttaagtc cagttgttgg ttcagagcag ggaggcgtta
    91981 gacctgttct gataatacaa aatgatgtag gtaataaata tagtcctaca gttatagtat
    92041 cagctataac atctcagatt aataaagcca aattacctac tcatgtagag ataagttcca
    92101 atgaatatgg gcttaataaa gactcagtaa ttcttttaga gcaaattaga actatcgata
    92161 aaaagagact gagggaaaaa attggttgtc tagatgaaaa tatgatgata aaagtagatg
    92221 atggacttca aataagttta ggattgttta ctttttaaag agggatttgt cttttattag
    92281 acaatccctt ttttctttta aatatctctt aaggtttaat tttaatgtac tatgttaata
    92341 aaattaaaaa taacgcaaaa aaatagcata aaagtgatat aataatatgg aattgatata
    92401 aaattacgaa ctcaagggag gtaattgcat gagagaccat aaaggattaa atgagattgc
    92461 gcgtatcata agaagagata tagtttcaat gatacataga gccaaatctg gacatccagg
    92521 agggtcatta tcagtagttg aaatacttac tgcgttatac tttgatgaaa tgaatgtgga
    92581 ttcttcaaat cctaaaatgg aggatagaga tagatttgta ttatcaaaag gacatgctgc
    92641 accagcatta tatgctacat tggctgaaaa aggttatttt gataaggaag aactgaatgg
    92701 attaaggaag ataggaagga tgttacaagg tcatccagac atgaaaggca cgccaggtgt
    92761 ggaaatatct actggttctt taggtcaagg tttttcagtt gcatgtggta tggctatggc
    92821 atcaaagttg gataatgctc cgtggaatgt gtatactttg cttggtgatg gtgaggttca
    92881 agaaggaatt gtttgggaag ctgctatgag tgctgcacat tataaacttg ataatttaat
    92941 tgctttttta gataataatg gacttcaaat agatggagat atagaaagcg taatgagtct
    93001 aggttcaata gttgataaat ttaaagcttt tggttggaat gtaattgaga tagatggaca
    93061 tgattttgac caaatatttg cggctcttga tatagctaaa tcaacagtta aaaaacctac
    93121 aatgatagtt gcaaaaacta taaaaggcaa aggaatatct tttatggaaa atcaagcagg
    93181 atggcatggg acagctccaa gtgatgagga gctagaaaaa gccttgcttg aattaggagg
    93241 tgctgacaat gagtaaaatg gcgacgagag aagcatatgg taaagcatta gtaaaattag
    93301 gtcaaataaa tgacaatgtt gtagtattag atgcagattt atcaaagtct acaaaaacac
    93361 atgattttta caagtcattt ccagatagat tttttaatat gggtatagct gaacaaaatt
    93421 taataggcgc tgcttgtgga ttatcaactg ctggtaaaat accttttgca agtacttttg
    93481 ctatgtttgc tacgggaagg gcttttgaga ttataagaaa ttcagtttgt tatccaaagc
    93541 taaatgtaaa aatatgtgct actcatgcag gtcttactgt tggagaggat ggagcatctc
    93601 atgaaagtgt ggaagatatt gctataatga gagctatacc aaatatgaca gttcttgttc
    93661 cagctgatgg agttgaaaca gaaaaaatta tttttgaaat agctaagtat aatggacctg
    93721 tttatgttag attagggaga agttcagtac cagttttatt tgatgaagat tataaatttg
    93781 aaataggaaa aggtacagtc ttaagagaag gaaaggatgt atcaattata gcttgtggaa
    93841 ttatggtaaa tgaagctcta ttagcacaag aaaagttgca agaagaaggt ataagtgcta
    93901 gagttataaa catgtcctcg ataaaaccta tagacaaaga tttaatatta gaatcagcaa
    93961 aagaaacgaa tgctattgta actgtagaag aacatagcat aattggggga ttaggttctg
    94021 ctgtaagtga ggtagtagga gagtcttgtc caaccattgt aaagaaagtt ggaattaaag
    94081 atacatttgg agaatctggt actccaaatg aattgttaaa aaaatatgaa ttaacttgtg
    94141 atgacataat aaagactgtt aaagaagcta ttattgcaaa aagaatgtaa gagatataaa
    94201 ttattcatgt ttgttaataa tataatatat ttaaaagaga ggtataaagt gttatattaa
    94261 tttatatctc tctttttttt atatgatatc aatatatcaa aaatgtaata aaatattcaa
    94321 atttttacaa aaatagagaa aatattcaaa tatatattga ctattcagaa aaatatgact
    94381 aatatataat ttatagagaa actaatttta tatataatga ctacttagat aaaagaatct
    94441 aaaaaaatta tgagaggagg agtagggtat aaaatcagat tataagtttt aagttattat
    94501 actaaaaagc tataaaacag ttatcatgta ttttatgtta aaggaaattg taggtagttt
    94561 atcgaattgt ttaatcagaa gaaaaaattt cacatgggga ggtaactgag atatgtcaga
    94621 aaaagtaaat gttaaaacag tcatcagttt cgcaggtgcg tatgtagcaa cagtaatcgg
    94681 ttctggattt gcaacaggac aggaaataat gcaattcttc tctttttatg gttttgcagg
    94741 tattattggt gggataattt caatggtatt attctcatgg atgggtgctt cagttatgtc
    94801 aaaaggtaaa gagcttcaac ttaaagaacc tatcaaaatt tatcgtgttt attgtggtaa
    94861 gtatttagga atattctttg aatggtttgg acctttattc ttatttggtg ttttcgtagt
    94921 aatgatttca ggagcaggag caactttaac tgaatactat ggattaaatc catttgtagg
    94981 tagagtaggt atggcagtag tagcattatt aactgtttca ctaggtcttg ataaattatc
    95041 aaagatacta ggtggaatag ggcctataat aataatcttt acacttttag ttggtggtat
    95101 aagtttagct aaaaacatag gtaatatagg agaagctgca caagttctta gcactgtaaa
    95161 gatagctaaa ccagttccaa atgcctatct atctggtgta atatatacta cttataacac
    95221 aattgttgtt atggcattct taactggatt aggagcaagt gctgctaaca aaaaagaagc
    95281 tatttgtggt ggtatattag gtggagtagc acttatggct gcagctataa tgatgcactt
    95341 agctattctt tctgatatag gaaacttata ttcaaaagca ataccatcat tattcttagc
    95401 agataagatt tcaccagtaa ttggagtttt attctcaata attcttatat taggtatata
    95461 tacaacagct gtacctttat tatggtcagt aactaataga tttgtagatg ataaacatcc
    95521 taagtttaaa ttaataactt taatagcagc tatattaggt cttataggtg gcttcctacc
    95581 atttgataag ctggttggta ttttatatcc atatactgga tatatgggcg tcataatact
    95641 ggtttgtgtt ctttatagac agattacaaa aacatctgga tatcaagaag gaatcagtga
    95701 caaataagta ttttttaata ttgtaaactc aagagctata tgaaaacaat gaaaatgttt
    95761 tcatatagct ctttttattt tttagctcgt ttattatgaa atagaaaaaa catgtttttt
    95821 agttacatta catatattta taattatgta taaatatata ctaatcaata atttagagtc
    95881 taagataagc ttataaatca tatatttaga atatatggga ggagtgataa gattgaatgt
    95941 aaagtttaat attaaaggta taatttatgg agttatagct cttgtattcg ttataggggg
    96001 atttatattc ataccaagta tgtttgtaga gaaatctaaa cccatagatt atacagtatt
    96061 acaaagaaat tcaataccag aaaagatatt agatgtgatg gataagtata caaatgaaga
    96121 aagagcatta gcggctaaaa tcgataacaa aatatacatt atagtgacta gaggaaataa
    96181 taaatatggt atagaaatgg acaaaataga aagtgtggtt gaggaaggaa aggatgtttt
    96241 gagagtcaag ataaagtata aagataagga agattctttt ccatacatag ttgttgaaac
    96301 aaatatgagt gaacttccag atagaataga attaaatgcg acgaaataag aaggtatttt
    96361 ataattaaat aactgcatat tgtacaataa agtcatggtt tttattaatg taagtaaatt
    96421 gtatatggtt cttattgttg taaaagccat gacttaaaat gcttataaag taagatatta
    96481 acagtagtat ttattactac attaaatggg gtctggaaat acttaatatt ctaattattt
    96541 ggagtgataa ttctagtttc agtaactatg tagtctaatt gtgcatcatg agtttctttt
    96601 ggaatagaat cgaatatctg gaagtcaaat gctatgccga tagttatagc atcttttctt
    96661 aagttttcta aaaatctatc ataaaatcct ccaccatatc ctaatctata gcaatgtata
    96721 tcatatgcta cagctggtac aattacaaca tctaaggcct taatatcaat tgtaggtgat
    96781 ttttcattag gttctcttat tccatatgct ccaattctca atccctcttt taaatctgtt
    96841 atttgagtag ggattaatgt atgattttct tttattgtga tgggacttga tactatttta
    96901 tttagagaca aaagtttttt gattaaatta tctgtttgaa cttcattgtt aaaatttagg
    96961 taaagcatta tattagttgc atttcttata tcttccattt gaagtaattt ttcagttatt
    97021 aaatttgaat tactaagtac aaagtttgca ctcttatttt ttcttgattc aataactttt
    97081 tttctaaatt cttttttcat aaaataattc ctcccttaat atgttataat gtgtacagca
    97141 attgtattta atataaattt tagtataatt tattgtaata aagcaatata tttgggtaaa
    97201 tgtaataaaa ataacagcta gtcatataat aataatagtt tatgtaaaag gagatgtatc
    97261 ttgtgatttc aaagaagaaa gctatttttt taggggtgat tttagtaatt ataacagcta
    97321 tggttacatc agcatttcag ttgacattgg ggaataaagt tgtaatatcg aaagaactct
    97381 atgaagacta taaaaaatat gataagttgt taggactaga atctattata aaacaagatt
    97441 tttataaaaa agtatcagat actgatttgg taaatggagc agcaaaaggt ctatttctag
    97501 gaacaaatga taagtattct ggttattata ctaaagatga aatggagaat ctaattaatg
    97561 atagtgaagg ttcttatgtt ggtgtaggta tgtatatagg ggcatcaaaa gatggtggct
    97621 tagtagtagt tcccatgaaa gattctccag cagagaaagc aggtgtaaaa tcaggggata
    97681 aattagtaaa agtcaatgga aaatctgtct catataaaaa ttcagatgaa gctgttcgta
    97741 tgatgaaggg taaaaaaggt aaaacagttg aactgactat attaagagaa gataaacaat
    97801 tgaactttaa agtaaaaaca gaccagataa ttgagaagag tatagaaagt aaagtaattg
    97861 ataatgattt aggatatata gaaattaccc aatttatatc aagtacatat actgactttg
    97921 ataaagcttt aaaagaatta aaagcaaaaa atatcaaggg attagtaata gaccttagaa
    97981 ataatcctgg tggaatgcta gatatatgta aagaagttgc tgatgagtta attggtgaag
    98041 gaaccatagt atatacaaaa gataataagg gaaatactga gtacttgaaa tctgataaag
    98101 aaaaattggg acttccaata gtagtgttaa ctaatggaga aagtgcttct gctgctgaaa
    98161 tattaacagc tgcaatcgtt gataataaag aaggtatttc tgtagggact acaacttttg
    98221 gtaaagggtt ggtacaatca gttgtaagat tgaaggatgg aacaggatac aagttaacta
    98281 ctgctcaata ttttacacct aatggagatt atatcaatga aaaaggtata aagcctacta
    98341 ttgaagaaaa agatgaaaat aaacagttag atgtagcaac taagtggctt agagaacaga
    98401 ttgataaata ggatttaatt tttataaact tatactataa aataaagaac attataagag
    98461 agatgtctca aaatgaactt tttagttcat gagggagtct ggaaatattt atgtgtattc
    98521 tttaaataaa aatttatttt ttaagtgata attaaatttt tacagatagg gctgtggttt
    98581 taaaaatcat agccttattt tgatattttt taaaaacata ttgcaaccca gttgttccaa
    98641 atattatatc atttactttt aaaatatcgc aaactgcata ttatatattt attataatat
    98701 aatttatcta actagaacct cagtttacta attaaattag atgcatagaa taactttttt
    98761 aaacattgaa aataaattaa actctaaaca catttaaata taaatttata tatcattttg
    98821 acttggttaa acaatttcat acttatcgat ataaaaatag gttataatat aaatgttcat
    98881 tatcttataa cctattttat ataatttatt cctaaaacat gtgaatgttt tttatgatat
    98941 tttgaagaaa ttataaaatc actttataat tgaatattat atataaatta atttaaatat
    99001 agaaaggaaa atatatgtac aacaatatca aaaatatttt aaaagaaaat catataacgt
    99061 ttgaagaata tgaccatgaa cctattttat catttgaaaa agctaaagaa ataagagaaa
    99121 aattacaata tactggagta gaaagtaaaa gtttatttat aaaagatagg tctggaaatt
    99181 actatatatt tgtaaccaca gaaggaaaaa aattagatcc aaaaactata aaaaatgttt
    99241 taggtggaaa agtatctata tgttcaaaag aagaattaac acaaaaaaca caatgtttgc
    99301 ctggatgtgt atctcctttt ggatatgaga aaaatatctc tcttgtaata gatcaagata
    99361 tatttaacca tgataaaata atcttttcac cagggatacc agaaaagaca tttattatta
    99421 cagctagtgg atttaaaaaa gtaataaaca atataaacaa tacaacttat aaatatatat
    99481 atattaatga attttaatca taattgtaaa ttagagaaaa tagcattaga aatcatgctt
    99541 aactatagtg taaataaatt atattcaaca caaaagattg atgctattat tacaatagtt
    99601 actgttaagc tcaaattcaa tgtattatga gttattattt ttaaatttta attacaaaag
    99661 cagggtagtt ttaactactc tgctttatat ttaacataaa atatataaaa tcaacaaaat
    99721 gattttagtc tatctattag atattcttcg ctctcaatgc ttagaacttt tagatatata
    99781 caataagtgc tttcatttgt aaaaatttct atagtattat cttgtttatt tacacctaca
    99841 atatctttaa aattgatatg atttttagta tttttacatt tgaaaatata tctgttatca
    99901 atcaaaatct catcattagt aattgaaata tagggtttat ctcatgcttt attaaaaatt
    99961 tatatgtttg ctcaagataa aaacttacaa ataataatag aaaagttact ttaaatgtac
   100021 atattatcga aaatattatc acaaaaatac ttataatata tatttgttta aaataacctc
   100081 tatcgcaata atttattaac gatatggaaa taaaagtgtt aaatcagatt ttggagaaat
   100141 aactttaaat atttccagac tctttttaga cagcctccat aaccttatat tgaacctatt
   100201 tattaacttt gtacttacag ataccattta tataagtttc gtgtatatta aagtcattat
   100261 ctgttactat aaagtctgca tccatacctt gatatataga gccacagaca ttatcaatat
   100321 tacaacttaa agcagggata tatgtagcca tttttattgc atcttctaaa gttgatatgt
   100381 tccaatcaac tatatttctc acagccttgt ccatagttaa tacacttcca gctaaactcc
   100441 cactatttaa tcttgcaaca ctatttttta catttacatt aaacttacca agagtatatt
   100501 ttccatcctc catagcacca gctctcatac aatctgtaat taaagctatg ttattactag
   100561 acttagcatc catcattatt ttaacagcta ttgggcttac atgatgacca tcacaaatta
   100621 attcagcata agtatctttt agtaccatag cagccccaac cattccaggt tctctatgat
   100681 ttaaaggact catcccatta tatgtatgta caaacacttt agcacctgaa ttaacgactt
   100741 gtttaacttg ctcaaatgta gctgaactat gaccaagaga aactgatata ttatttttag
   100801 ttgcatatct tgttaattct attgaacctt tacgttctgg agcaattgct attttcctta
   100861 ttaaattttt cgattttttt tgccataatt ttaatatatt gatgtcaggg tctttaaaat
   100921 atttttcatt ttgagcgccc ttatattttt ctgtaaaaaa tggaccttct aaataaatcc
   100981 cttgtatttt tgcaccctca actcgattga agctattgct tatattttct acagaatcac
   101041 ttagtgtatc tacagaatca gttaaagttg taggtaggaa agatgttact ccatatttta
   101101 ataagccttt tgaaattgtg tttattgctt caaatgtatt gtccatgaca tctgcaccta
   101161 aaagaccgtg aatgtgagta tcaactaagc caggagcaat atatttacct gaaaaatcta
   101221 taacattatc agtattatta ggtctttctt gttgaaattc accgaatttg ccattaatta
   101281 tactaaggta acctttttct ttgattccat gtttcataaa aaatttatct gcataaataa
   101341 aacttttcaa aataacctcc ttataattat actatcattg tggcattgac gcttataata
   101401 tcattctatt ttcttgaaag ctatttaact tactatctta catgtcttac tctatataca
   101461 aatttatcgc ttctagcgac actcaaagta aattcaataa ctatattgtc atcattatat
   101521 gtggtacgaa gtaatttcag acaaggtgaa tctcctggta cttccaataa cttagcttcc
   101581 ttatcagaga ttattccagc tgaaaattct tcatcagcaa ctttaataat ctcgccataa
   101641 tcttctctaa atatttcata taaaggtttt tgttcgattt tttcttttgt caatcctata
   101701 aattctttca taggaagata tgttctttca agcatcatag gaaggtcatc agcaagtctt
   101761 aaacgcatta tttttatcat tttttcacca ggagttatac ctaatttttc agagaaatac
   101821 tttgtacttt ctactacctc aaatgataat acctttgtac ctggcttttt tccttgtgtt
   101881 ctcatataat ctgtaaagct ataactttcc attaagtttt gagaattttg acttagtgca
   101941 gcaacaaaag ttccttttcc atgtcttttg tatatatatc ccatatgctc taactcagcc
   102001 atagctagtc taactgtggt tctacttact ccatattcat cacaaatttt tctttcggaa
   102061 agcattctat cgtttggttc catctcattt tcaatcttag ttcttaatat ctcaacaagc
   102121 tggtcatata ttggtctttt atcatttctt tttatcataa aaatatagtc ctttctaagt
   102181 ggttattacc acaatttgat tatagaatat agaattattt atgtcaatga ataaagttta
   102241 atcaaaattc aataagtaag gctattaatt tattataaaa ttatggtaca ttgacaaaac
   102301 aagtaaaata atttatattc aaattggtaa taaccacttt ggatatatta tatgaggtat
   102361 tttttatttt acagattaat ttattgttta gaaaagtaaa aattaataat gaggagaatc
   102421 tagtatgatt acagtaataa cattcaaccc atctatagat agaatgtata gagtgaataa
   102481 tataaacata ggtgaggtgc aaagggtagt aagtaagaat gcaactgctg gaggtaaagg
   102541 attaaacgta gctaaggtat gtaaaatttt aaaagaaaat cctttagcta tgggatttct
   102601 aggcggattt aatggagaat ttataaaaaa tgaacttaga aaactagata tacaaaataa
   102661 atttacaaaa atagagcagg aaactagaaa ttgcttaaac ataattgagg acaataaagt
   102721 tagtacagaa tttttagaaa aaggaccaat agtagaaaaa agcgatttag agagatttga
   102781 aaatgatata gaggaagtac taaaaaatac taaaatactg gtagcttctg gtagttattg
   102841 tgagaatatg ccgatagact attatgaaaa gataggaaat atatgtagag caaataatat
   102901 aaagtttata ttagatacat caggagaagc attaaaaata gctttaaaat caaaaccata
   102961 tttaataaag ccaaatatag atgaaataag acatttatta ggaatgaata tagaatcaag
   103021 agaagaaatt atcttgtcag gaaaaaaact tattgaaatg ggtgcagaga atgtatgtat
   103081 atctttagga aaagatggta tggtgtattt aaacgaagat aatgtatatg atgtaaaagt
   103141 accagttgta aagtgtataa atactgtagg tagtggagat agcacagtgg ctggatttag
   103201 tgtaggtatt ttaaggggtt ataaaataga aaatttactt aaatttgcaa atgcttgtgg
   103261 tataagtaat gctttaaata tggaaactgg atttgtagat ttggtagaaa ttgataaata
   103321 tcaagattta gttgaagtaa aaaagttaag ttaaatacat ttaatgggaa tataataaat
   103381 ttaatgttgt tgtaatagat tttaatttta atataaaaga tatagtctta tataaaaata
   103441 ggttagaaaa attcattttt aacctatttt tataataaat atctatttta ctgaatttat
   103501 aattttctct agtaatcttt gagccttgat acactcttct ccattaatag ctggttttat
   103561 attattttct atacaatcaa taaaatgatt tgatatatcc tcaaaaccct tttgttttaa
   103621 tatgtttacc catgcaccac tttgctttaa agttaggttt ccaccttctt ctatttccag
   103681 tacattaaga ttcttaactc tttgaatatt accctttgaa agaatttcaa cttgttctaa
   103741 ctttgttcca gaatctctat gcatagaggt gtttatagag aaatttttac ctttaagttt
   103801 atgacttaca aatataagat tcttattgtc tgttaaaaat aaatcctctc cactaatttc
   103861 aacatcttca tttgctaacc ataaagcagt gtcaataaca tgtatatagt catctataag
   103921 agtactgtcg aatttaacat ttcttaagga atttaatcca tgtttacata tattgataga
   103981 tacaatttct gtagcattat ttttaatttc tttgtacata ggacagaatc tacggttgaa
   104041 tccaaccatt aaatttaagt tttttttcgt acttaattcg ataagttctt ctccttgact
   104101 tactgttgaa gcaagaggtt tgtctacata tacatgaaca cctaaattta ataatatttt
   104161 tataatttcg tagtgtgttt ctgtagagct atgtagaaaa atacaatcac attttttagc
   104221 tagggattca atagaatcga atggcatgat tctataatca ctacagactt tttccctttt
   104281 aactttattt ggagtaaaag ctcctacaaa ctcaaatctc tcagacttag ttaatatagg
   104341 taaatatgcc ttttgagcta tggagccaag acctatcatt cccattttta tatttttcat
   104401 aatactttct cctaaggttt ttatatttac agaattgatt ataattcaga cacataaatt
   104461 tgtaaacttt gtatcaaaaa ataaatttaa agcttatata agtaaattag cgaaataaga
   104521 aatattgata aagtaatttt gtaggatatc cataaaattg attgatataa atattttatg
   104581 tattgacaaa aaattcaaat taatttatat ttggattagt ggtaattacc actttggtct
   104641 gaacaagttt ttatcgtaaa ataaaaatac taaagtatat agagtatgat tttattaaat
   104701 ttttaaagat aaactataaa attaattaaa atctatagtg tatattttat agtgagttta
   104761 agtagtacta aaaaatctaa gcaaaaaatt ataaaagagt atattttttt atagtttaaa
   104821 gtggttataa cctcattacc aaatgtaaac gttacaagta tgaaaggaga atgaaaatgt
   104881 ttaaattaga agaacaaaaa ctaaaagatt taggtgcaat aataacaact aatgaaataa
   104941 aacaacagcc tgaattatgg ttagaaactt atgaaatata taaatctaac aaagaaaaat
   105001 taagtagatt catagataca ataagcaata atcatgggca gtttagagtt atatttacag
   105061 gtgctggaac ttcagcttac ataggaaatt caatacttcc ttaccttaaa aataaaaatg
   105121 acataagaaa atacatattt gaagcaatac ctactacgga tatagtttca aacccatatg
   105181 attacttaaa aaaagatata ccaacattat taatttcatt tgcaagaagt ggaaatagtc
   105241 ctgaaagttt ggctgcttta aatttaggga ataagattgt agataatttt tatcatttag
   105301 ctataacttg taatccagaa ggagaactgg ctaagatgac taaaaacgac gaaaataatt
   105361 acttgttatt aatgccatca aaatcaaatg atgaaggctt tgccatgaca ggaagttttt
   105421 cgtgtatgat gttatctgct atgttaatat tcgatagttt agaagatgat gtagaaaagt
   105481 catatataaa tgcaataatt gaaatgggaa gaaatgttat agatagaaaa gatgaaatac
   105541 atgagttaat aaataaagat tttgatagag ttgtatattt aggttcagga ggattaggtg
   105601 gtttgacaca agaagcacaa ctaaaacttt tagaacttac agcaggaaaa atatctacag
   105661 tgtatgattc tcctatgggg tttagacacg gaccaaaatc atttattgat gaaaatacac
   105721 ttgtatttga atttgtatct aactgtttat atacaagaaa atatgattta gatgttttag
   105781 aggagataaa aagggataaa attgctaaat tcacttgtgc agtgtcagta gaaaatgaaa
   105841 ataacttctc aggaacaaag tttgagttta aagaaaagta taataaatta ccagatgtgt
   105901 atcttgcaat gccatacata ttgtttgcac aaactatagc attgtttgta tcggtaaagg
   105961 ttggaaataa gccagatact ccatcagcta caggaacagt aaatcgagta gtaaaaggtg
   106021 taacaatata tgaatattaa aagataagat taaaatatta taactaaata atttgggagg
   106081 gtatcaatgt ggcattagta acaacaacat caatgcttaa aaaggcacaa gatgaagggt
   106141 atgcagtagg agcatttaat gtagaaaata tggaaatggt aattgctgtt atagaagctg
   106201 ctgaggagtt aaattctcca gtaatattac aaactactcc atctactgta aaatatgcag
   106261 gtcttgatta ttatctagca aatgcaaagg ttgctgcaga aagagtaaat atacctgtag
   106321 caatgcatct ggaccatggt tcaagttttg accttgcaat gaaagcttta agaagtggat
   106381 atacatcaat aatgatagat ggttctcatg aaagctttga aaataatata tctatatcta
   106441 aatcagtagt aaaagcatgt agtccttctc ttataccagt ggaagcagaa cttgggaaag
   106501 ttggtggaaa agaagatgat ttagatggcg ggaatagtaa tgattataca aatccaaaag
   106561 aggcaaaaga gtttgtcgat agaacaggaa tatcttcatt ggctattgct ataggtactg
   106621 cacatggatt gtataagggt gaacctaaaa tagatttaga taggttatca gaaattaaaa
   106681 atgtagtttc aataccttta gtattgcatg gaggttcagg aatacatgat gatattataa
   106741 aagaagctat aaaaagaggt attgcaaaag ttaactatgc aactgaatta agaattgcat
   106801 atagtaaagg ggttaaaaaa gttttagatg aagattctga ggttatagac cctaaaaagt
   106861 atggattagc agggcttcaa tcagtaaagg attttgtgaa agaaaagatt aaagtgtgtg
   106921 ggtctgtaaa tagagtataa aaataaaata tcctaaattt attttagata agtttaggat
   106981 atttgttata tgaaaaattt atattaatta tatgtaaatg gtgtattttt ttcatttaat
   107041 tgatgaaaaa tatcagcttt tattggtaaa gtattacata tataattaaa atatactaaa
   107101 aattgaacta tatattttat tattataaaa tatttatatt aaattgtgga attaaaatat
   107161 actaggatat aaaattctta aataaaaaga aaagattgtt tttataaaaa atatttttta
   107221 taccacttta aaaaacacaa taataacact gagggaggtg gggatatgag agaacgcatt
   107281 attcttgaaa cattaaaaaa tagtagtggt tatctaaaca tagattattt tgcagataag
   107341 ttgggggtat ctactcgaac tatcagaaat gaaataaaaa agatagaaac tataaaagaa
   107401 tgtaatggtt ttaaattaga atataagtct aaattaggat atattctaaa tattaaagac
   107461 caagataaat tcgagcatta tctaagaaac ttaccctcag atttagttga aaatccagaa
   107521 caacggttgg agtctataat agtagagctt ttagtaaatg aaggttataa aactatagaa
   107581 cagttaagta aaaaatttct agtaagttca tcccaaataa aaaatgattt aaaaaagata
   107641 gatgaaaaga taaaggatac agaattaaaa ctagagcgaa aggctcatta tggaattaaa
   107701 atagaaggtt ctataaaaga aattcaaagt atattggtgg atagttattt tagagggaat
   107761 agaaatataa cagagtacag gaataagttt atagataatt taaaattagc taatattaga
   107821 agtacaataa aaaatgtact taatgaacat gatttagaag caaatttaac agaacttgag
   107881 gaaatattag cacaaattat tatattgtat ataagagtta gtatgagagt agtgggaaat
   107941 gctagcgatt taaaattata tacagaagat ttaattatag ataaattatt agataaaatt
   108001 tttagagata aaaaatataa ccttaattat gatgaaaagt attatttaaa ggagcttata
   108061 aaactaaaga ctaaagataa gaaagccact ataaagaata ttgataagaa taaacttcaa
   108121 gatattatgt tcgaattttt tagagagata gataaaaaat ataactctaa ttttttagaa
   108181 gataaagagt tttttaactt attttactta catattgcat gtttaataga acgtataaag
   108241 aagaaccaca agataataaa tcctttttca gttaaaataa gtcaacagta tccaactgtt
   108301 tttaacttat ctattcaatt ttcaaaaatc atagaaaatg agtatcatat aaaaataagt
   108361 caagatgaaa tagggtttat agctactcac attgctgttc cttttgaaaa gagagaagaa
   108421 gctaatttta ataaaaaata taaaatagca ataatatgct cttctggtgg aggtagtgca
   108481 tttttgataa atttaagact taaagaaatt tttccaaatg ctgagataag aaatttttca
   108541 ttactagaag aaaaagctgt aatagaattt gcaccagatt tgattttttc aataacaaat
   108601 cttttatttg aaataaatgc tccagttata cttataaatg agattttaga cgaattggat
   108661 tatttagata ttaaagaaag tgttagattt gcagaccata taggaaatat atcaagccca
   108721 aaacaatata tattaggtct atttgataag aatcacttta ggtgtataaa agataaagct
   108781 aagtataagg atatccttga tagtatgtca aaatgtatag ttgacgaggg agcttgttct
   108841 ccaacctatc ccaaagatgt atgggaaaga gaaagctatt tgagtactat ttatacaaat
   108901 ggggtggcta tacctcatcc aatcgagatg acaggaaaca aaaatataat atcagtagct
   108961 ttgatacaaa ctgatattat ttatgaaaat agggtgccta aaattatttt catgatttca
   109021 ttaataaagg gaaatttaga acttcataag caaatatcta aatatttaag taagattatg
   109081 gcaaataagg atatggtaga catgctaaat aagtcacaat cttatgaaga gtttatgtat
   109141 aagttaaaaa tctatctggg aggttagaca tgaatataga gttttttaag aggttgtcag
   109201 aagcagatgg tatagcatct aatgaagaag aggttagaca tgttttattg gaagaactaa
   109261 aagcttatag tgataaaatt atctgtgatg ggctagggag tatcatcttt tctaaaataa
   109321 aagatgagag tgcaccaaac gtaatgattt gtgctcatat ggatgaagtt ggatttatgg
   109381 tgagaagtat agacaaactt ggtatgattc acttaataac aataggagga gtaaaacctc
   109441 ttgcacagtt tgtacaaaaa gttagaatta caacaaaaga agggaagaaa atccccgctg
   109501 tcataaatgc tacatataat aatggtaagg ctgaaaatat atatgcagat attggagcat
   109561 atacagaaga agatgtatat aacctaggga ttaatgttgg ggatatggta acatatacaa
   109621 caagctttga ggaatttact ttaccagacc gattagtggg aaaggctttt gatgatagga
   109681 taggatgttt tgtgatggga gaagttttaa aagaacttag gaaagaaaat ctaaattgta
   109741 atattcactt tgcggctaca agtagtgaag aggttggaat aaggggagca aagacatcaa
   109801 cacagctaat aaatccagat atagtatttg taatagatgt agcatgtgct aaaaatgagt
   109861 ttgtgagaga ctatacaaat cagaaacaaa ttgataaagg tgtaatgcta atgcatagag
   109921 ataggactct agtccctagt agaaaaatga tagattatgt aatggaaatt gctgataaaa
   109981 ataatatacc acttcaacat gatatgtttg aatcaggtgg gactgatgga ggagaagcac
   110041 atctcgtaaa tgaagggaaa ccttgtgtag taacttgtgt accagttaga tatggtcatt
   110101 gtgcattttc aatagtaagt aataaagatt tggagaacat tataagattg tatacacagt
   110161 taattttaaa ttttgatgaa gaacaatata aacatataag aaattttatc taaaggagaa
   110221 taagaaaatg tcaacagaag tacaaataat ggaacttata tcaactgcag gagagagtaa
   110281 atcgaaagct tttgaggctt taaaaaaagt gaagtcaaaa gattttaaag gagcaaaatt
   110341 gttaatagag gaggctcgta aaatagatat tgaagctcac aggatacaaa cagaattaat
   110401 aactcaagat ttaaatgaag atgttgaaag tccagcaatg agtcttttaa tggtacatgc
   110461 tcaagaccac tatatgactt ctcagctagc aaaagacttg atagaggctt tgatatattg
   110521 tctcgataag taattgtaat gtagaaatag attatttatg taaaaattct tttaaaagtt
   110581 tagatgcttt taagagataa taaaaataca aactttagga ggaattatta tgaaaatatt
   110641 attatgttgt gcaggtggat tttctactaa tatgttaatg caaaatatga aaaaggtggt
   110701 aaaagagagt gctaaactca atgaaaaaga ttttgagttt acagctatac cagcagattc
   110761 aatagaaagt gaagttgatg attgggatat agtacttata ggtcctcaaa tagctcacaa
   110821 aatagacttc ttaaaaggaa tattagagcc aaaaaataag ccttttgcag taatagataa
   110881 agatgtatat ggaaaaatgg atggagctac agttatgaag ttggcattaa taacttataa
   110941 gaaacatcaa ttagctcaag gataataaaa ataatgaggg aaaagggaga ttagatatgt
   111001 tttcaaaatt tgaagcattt atgaatagag tatttatgcc tttagctcat aaggttgaca
   111061 atcaacgtca ccttggttct ataaaggctg gtatggttgc tatgacacca ttcacaatat
   111121 taggaagtat atttgcaata cttccagcac ttccaaatat gcttggagaa aataatccaa
   111181 taagcaaatt catacttaac aattcagcaa tattggattt accagtaagt ctttccatag
   111241 gtttaatagg attatatgct tgtatgtgta ttgcttttaa tctggggaac tactataaat
   111301 tatatatacc aggttgtgtt gcactatcaa ctttttcttt tttattccta gtagcctcat
   111361 ttacaccaga tggagcttta gaaataggaa atttaggagc taaagggcta tttacaggta
   111421 tgatagcagg gcttggttct gtggagttat ataatttttg taataagaag aatatcacaa
   111481 taaaaatgcc agaaaatgta cctgattttg tatctaggtc ttttgaatta atacctacta
   111541 ctataatagt ttgtggaact tttatagttg ctcgttttat ttcattaaaa gtatttggag
   111601 aattacctcc acagatactt actcaatttt tatctccatt agtaggaagt atggataacc
   111661 catggtcagt tcttgcactt aactttgcta tatgtactat attctttttt ggaatacatt
   111721 catcagtatt tagtcctata actagaccta taatgattac atttatagct gaaaacatag
   111781 cagctatgca agctggagaa acaatacctc atttctttac agcaggagct tcaagtgcat
   111841 tctttggatt tacaggatgt ggaattagta taggttgtgt aattgcatgt atgttatcaa
   111901 aaaatgcttc ctataagaag attggacgtg tatcattatt ccctgcatta tttgggataa
   111961 atgaaccaat attatttgga gcaccgataa tattaaatcc aataatgttt ataccacatg
   112021 tatttggtgg agctataata ggtacactac caatgttttt tatgcactgg ggatggttag
   112081 caaagccagt atttgaccct ccatatgtag gggtattctt agaaggattt ttaactaatg
   112141 gagattggca ttctatatta gcaaatgcat tgcaattagt attagcagtt ttattatatt
   112201 ggccattctt taaaataatg gaacgtcaac aaaataataa aaaacaaaaa gaagaaacta
   112261 agaatatatt ctctaaagaa gaagaagact tattggatga tttaggattg gatttctaat
   112321 attttgttat gaataataca atggagagat tagtatcctt aatctataaa agaggtgttg
   112381 acgctctttt gattaaagca aaaaatacta aaagatatat aggagcttta tcaggtagtg
   112441 gtgtatatgt gcttgttact aaggataaaa attatcaaat tctagatggc agatatattg
   112501 atgaagcaga taaaaaaacg actggtttca taaaaaggat tgtatctcaa ggttcttata
   112561 taccaactat aattgagtta ttaaaagaat taaatataaa aaagttagca atagaaaacc
   112621 aagctatgag tatacaagag tatctttcac taaaaaatga aggttttgaa atcaatttaa
   112681 taacaaatga attatggaag ctaagggcta taaaatctaa agaagaaatt gaacttatta
   112741 aaaaggcttg tgaaattaca gatgaagtat ttgatgaggt tatttctgaa attaaaaaag
   112801 atatgactga gctagaagta tcagctctaa ttcagtatca tgcattaaaa aaaggtgcaa
   112861 gtggaatgtc ttttgaaaca atagtggtat caggagaaag aggtgcaatg ccacatggaa
   112921 gacctacaaa caaaaaattg aaagtgaatg aagctataac aatagatttt ggtgttgttt
   112981 atcaagggta tcaatcagac atgactcgta caatatctat aggtaaacct cctaaaatta
   113041 ttaaagagat atatgatgta gtattggaag cacaattatc tgcaatagag tcaataaagg
   113101 aaggaactag ggcaagtgat gttgacaaag tggctagaaa aattatagat aaacatggat
   113161 ttggcgaata ttttaatcat ggactgggtc atggtatagg tcttggagat ggtgaagttc
   113221 ccactttaaa tccaaatagt gaagatatat tagtggaagg aatggtaatg tcttgtgagc
   113281 caggtattta tattccaaat gtagggggag ttagaataga agatgatatt gttataatag
   113341 atggaaaagg tgttccactc aataagacat ccaaagagtt tataatatta ggagagtaaa
   113401 attatgaaat ataattttaa taaagtatta aatcgtaaag aaggaaattg tagaaaatgg
   113461 agcaaccatg tgattaaaga aaaatttggc ttaaatgaag atgcaattcc tatggattta
   113521 gctgatatcg attttgagtg tgctcctgct ataaaagaat ctatcttaaa aagagcatca
   113581 gtaggagatt atagttatac ttttatagga gatgacttct atgatgctat tataaattgg
   113641 aataaaagaa gatttgatgt atatatagaa aaggattgga taaaattaac ttttggtact
   113701 gtttcaaccc ttcattatat agtccaagca tatactaaag aaggagaggg tgtattgata
   113761 aatacacctg cttatgaccc ttttgcagag gctgtagtaa ataataatag aaagttgtgt
   113821 tgtagctcat taaaattaga taacaataga tattatttag atttagagga tatggaaaat
   113881 caaatgaaat acgagaatat aagattgctt atattctgta gtccacaaaa tccatcaggt
   113941 cgtatatgga caaaagaaga actatatcaa gtgtcagagt tatgtttaaa gtataatgta
   114001 attttggtaa gtgatgaaat tcatagagat ataatattta aagattatag atttgtatct
   114061 ttgtggaatg ctcatccaga aatttataaa aatagtataa tctgtgtatc tcctaataaa
   114121 ggcttcaact taggtggatt aaaaacatca tatgtattaa taagagatgt aaaaattagg
   114181 gagactttat tagaaaggct aaaaagtaat tcaataactt ctccaaatgt atttgcaata
   114241 ccagcaatag ttgcagcata taatgaaagc gaagaatggc tagatgctat gactagttat
   114301 gtagaggaga attttgaaat agtttatgat ttctttgaaa ctaatatacc aaaagctaaa
   114361 gtgatgaagt cagactcttc ttttttagcc tggatagatg taagagaagt atttagaaat
   114421 gaagaagaat ctaaagaatt ttttagacat gcaaacttaa ctatggtagt tggaagttat
   114481 tttgtgaaag atggagatgg atttattcgt attaatgtgg ggtgtcctag agaaacatta
   114541 aatgaggctc taaatagaat caaaaaaacg tatataagta tgtattgtta aatcataaaa
   114601 aaagtatcta tggtttatat aaaaacacat tatttagtta tcaaatatta ctggaatttt
   114661 gtattccagt aatatttttt gattaaggaa tattattgag gaatattaaa taatattatt
   114721 tcataccctt atattaactt atataaaaat attttattat tttgggaacg ggttagctaa
   114781 cctttatcta gtgtatattt atattgtaag aagcagtaaa aacttttcct ttactaagtt
   114841 tattaataaa cttcttatct ttataaattt tgttagaatt tatactatca gcaagaccat
   114901 accaaggttc tatacataaa aaaggagcag tagaattagt ttcactataa taaggagtcc
   114961 aaataccaac tagagggaaa tcttccatag atatagttac atatttacta ccatcattat
   115021 tacatataga cacttcatct atgttggtgt atatcaaagc atcattcttg aatacttctg
   115081 gatttaactg taagtttttt aattttccaa taggtattat atcatctgta aaagaaccat
   115141 ttaaattgat tttttctaca tcatttttac ttttaaactc aaggtagtgt ttagaaaaat
   115201 cattttgttc gtaaaaagga aggttgaatg caggatgtcc acctatagaa aagaatatat
   115261 ctttagaatc agtatttttt acaatccatt ctacctcaat actattatca tttaatgtat
   115321 agtttatgat tagctcaaaa gaatatggat acttctttaa agtagattca ttatctgtta
   115381 atttataagt tacaaatgta tctcctttat ctacaatctc aaagtccata tctctagcaa
   115441 acccatgttg agtcatgcta tataaatttt cttctattat tgtttcatta tcaaaaagtt
   115501 tacctactat agggaacaat ataggtgatt gtctacccca atatttttta ttaccatccc
   115561 aaagaatgtt tttgtcgtat tttttagaaa atattttagt tagttcagca ccaaaactgc
   115621 ttgattcgat aattaaattt tcattttgta atatattcat ttaaaatctc ctttattata
   115681 ttttatgagt atattatact ataaagtata aagattatta aattttattt gatattatat
   115741 ttgaaaggta gattttagta tattttgaaa attttgtttt gaaaatttgg gattatttaa
   115801 gaaattttgt attataaata gaaggaaata gataaattgt atagaataaa atatattaag
   115861 ataagttaat aatgttaaat gggaagtgag tttatggaaa aaccaaatac aaaagttgtt
   115921 aactttcaag agtataaaga cagaaaaaac caaagagaag taaatagaga cgaactttta
   115981 aagcttataa aaaaaattgt gacttcaaaa tagggagttg ttaaactccc tattttaatg
   116041 ggtttcataa taattaagac attctaagtc catctatata atctttgaat tgtgagaaat
   116101 ctgattcact acttaattct atggtttctg aaccttccgt ataaaaattc ttaagataga
   116161 tagtataatt attatcaaca caatcatgat aaatacatct atatccatct tcatacaaac
   116221 tttttaactt agaaaaatca tccacaatat catctcctta aagttctttt aaatatattt
   116281 ttacaaaaag catctaattg tatgcaaatt gacaatgtaa aataaaggaa atgaacataa
   116341 aatgtagaat aatttttata tgtatgtaaa aataaaaaga aaaagttgaa atttttagaa
   116401 aataagagta ttttttatct aaaaagagag tttaaaaaat aaaaaaatgt tgggaggata
   116461 aaaaatgagt ttattagaaa gtatatcaaa aaacatatat tccctagata actcttctat
   116521 tgaaaaaaca aagcagagat tggataggct tatacatcca actggaagct taggaaagat
   116581 agaagatatt tgcatgcaat tagcaggaat atttggcaat gaaaattttg acacaagtaa
   116641 aaaggttata attgcttttg cgggagacca tggtgtatat gaagaaggcg tagcacctga
   116701 ccctcaaaat ataacaaaat tacagtttcc aaatttttcg aaaggtctat gtggagttgg
   116761 agtaataagt aaatttgtag gggcagatgt tgtagctgta gatgtaggaa taaactgtga
   116821 tgaaaaactg gatggggtat tagactacaa gataagaaaa gggacatcaa atatggcaaa
   116881 aggtccagct atgagtaaac aagaagcaat tagatgttta gagataggta ttgaaatagc
   116941 agagcagtgt atagaaaaag attataaggt tattggtatt ggggagatgg gtatagcaaa
   117001 tactactcca agtacagcaa taatatctgt aatttcaggg tgtgacccgt tagaagttac
   117061 tggtataggt gcaggtctta agaaagaaag actaaagcat aaggctgaag taattagaaa
   117121 ggctattgaa attaataatc caaatccaac tgatggagta gatattttat ctaaagtagg
   117181 aggatttgaa ataggctcaa tggcaggtgt tatattaggt tgtagtgcta ataggattcc
   117241 agtagtaatt gatgggttta tttcttatgc agcagcatta attgcatata agataaatcc
   117301 aaaaactaga gaatatatga tagcatctca tttatcagca gaatcaggaa ctaaaagagc
   117361 attagacata ttaaaattag accctctatt aaatatggat atgagattag gtgagggaag
   117421 tggagctgct ttagcatttg atataataga agcttcaaac tatacttaca aaaatatggc
   117481 aacttttgat gaaattgaca tgggaagata aatataaaaa tttaatatgt aggagtgttt
   117541 tgatgagtaa aattattcta gtaacaggag gagctaggtc agggaagagt aactttgcag
   117601 aaaaactatg ttttgacaga aataataata cagcttatat agcaacctct attccatttg
   117661 atgatgaaat gaaagataga gtaaaaaaac atcaagagaa tagacctaga aactggaata
   117721 cttatgaaat atatgaagat atatattcca taattaagga gatatataaa gaacatgaaa
   117781 ctgttatact agattgtgta acattattag taaataatct aatgtttgaa cacaatctaa
   117841 atatagaaga atctagtcaa gaagaaataa acaaattaga acaatacata aaagaacaag
   117901 ttgtcaaact tattgaagaa atagaaaaaa caaatctata ctttgtattt gtaacgaatg
   117961 agttaggtat gggaattgtt cctgggaata aacttagtag aatttatgct gatattgtag
   118021 gtcgtataaa tcaatatata gcttcgaaaa gtaatgaagt ttattttgta gttagtggca
   118081 tagctatgaa gataaaggag tagtatgcaa ttatgaaaag atttatttta atactacagt
   118141 ttttgacaag gatacctata aaattaaatg taggatttga tgatgaattt tataagtcaa
   118201 tagtatattt tccacttgta ggttttgtca taggtatatt atcctattta ataggatgga
   118261 tttctatgct tttatttgaa ccatttatag cttctataat aataactcta gctggtgtct
   118321 taattactgg aggacttcat atagatggat taggagatac atttgatgca atatatagtt
   118381 atagggataa agaaaagatg cttgaaataa tgaaagattc aagattaggt acaaattcac
   118441 ttctagcaat tatgtttgta cttttattaa aggttggatt cgtttacgat ataataagta
   118501 ataattcatt gtgggttata atttttatgc caatgattgc aaggttagga gtaatgttat
   118561 tgacatataa aactgtgaca ccaagagaaa aaggaatggg aaatttattt ataggaaaat
   118621 taactacaag tatgttaata actgctataa tatacacatt attgatagtt gctcttatta
   118681 ctaaatttat atttttatta cctaatatag tgttgattaa agtattaggt tcgattatag
   118741 tggtttttgt atttataata ttattcaaaa aacatattta taaaaaaatt gacggagtaa
   118801 caggagatat attaggctgt ggaatagaac tttcagagct tgtatattta atttacatat
   118861 atttgttaat ttttatgttt ttttaaagta aaaagtggtg ataatatgat aagattaata
   118921 ttaataagac atgcactgac aaatgataat aaaaaaggaa gattatcagg ccatataaat
   118981 agttgtatta gtgaagaggg caaactacaa ataaataaaa ttaccagata tctgagtaat
   119041 gaaaacatag ataaggttta tacaacacca tctacacgta ctaaagatac agtagaaaaa
   119101 atatcaaaat tgaaattatt agaaatagaa gaaaaagaag ctttaagaga aattagtttt
   119161 ggagactttg aaggaagaac ttttgaagaa attaaaatca aatatccaaa tgagtttgaa
   119221 aaaatgataa aagaaggtaa caactataga tatccaaatg gagaaagttt gatagactct
   119281 tataaaagag tggcgaaaga aattgataat ataattttag aaaatgatag taatttagat
   119341 acaaagacaa tacttatatg ttctcatgca ggaacaataa gaaatataat aacacatttg
   119401 atttctggta gttataagta tcactggaac tttaaaattg ataatgcatc tattacagtt
   119461 ttagaaattg atggtggatt tgctgtaata gataaaatga attttacaga cttcatataa
   119521 tttaatcaaa accaaacatt acaatctgtg tttgtaatat atctgtaaaa ttagcaatga
   119581 aaatagaata ttagattaaa attaggttct taattagatg ttaaaaggga aaaaggttag
   119641 atgcctttgc agcccccgct actgtgaaac caacgaaact ataaatacca ctgtcagttt
   119701 gatgggaagg ttatagaagt aggatgaagt taagccagga tacctgccta atttaattta
   119761 aaacaagagg tcttcggggt gaaagatttt taattaatat atataaaagt cctatcttta
   119821 gaagtattag gacttttttt aatttgtttt ttagtaaatt ttaacaagga gggatggaaa
   119881 gtggggaaaa aaataatgct acaaggaaca gcttcaaatg taggtaaaag tgtcttagta
   119941 gcaggtttgt gtagaatatt taagcaagat ggttatactg ttgctccttt taagtcacaa
   120001 aatatggctt taaattcttt tataactaaa gaaggattag aaatgggaag agcacaagta
   120061 tttcaagcag aggctgcgaa aatagagcca atagctgata tgaatccagt tttattaaaa
   120121 ccttctggaa ataataaaag tcaagttatt gtaagaggta aagttgtagg agaaatgcct
   120181 tcttctaagt atcatgatta taaattggag ttagtagatg tgttgaagga aacatttaat
   120241 agcttaaatt caaggtatga tattgtagtt atggaagggg caggaagtaa tgcagagata
   120301 aacttaaaag atagagatat ctctaatatg ggtatggcag aaatagctga tgcacctgta
   120361 ataatagtcg gagatattga tagaggaggc gtatttgcct cattagcagg aacaatgctt
   120421 ttattaaatg aagatgagaa aagaagagta aaaggtgtaa taatcaataa attcagagga
   120481 aaaaaagagc ttttacaaga tggtgtaaag atgctagaag acatcataaa agtacctgtt
   120541 ataggagtag taccttatac agatataaaa atagaagatg aagacagtgt aactacgaga
   120601 tttaagaaaa aaatgaataa aagtgatata cacatagaaa taattagaac tccacatatg
   120661 tcaaatttta cagattttaa tatatttgag acacaagaag atgtaagtat tagatatgta
   120721 gactatggag aatctttagg aaatccagat atattaataa tacctggaac taaaagtact
   120781 atagacgatt taacatatat aagaaaaagt ggtcttgaat cgcaaatcaa aaatttacat
   120841 agtcaaggta aattgatatt tgggatatgt ggtggatacc aaatgttagg taaaaaatta
   120901 aaagaccctt atcatgttga aagtgaaatt gaagaagttg atggaatagg tcttttagat
   120961 acagaaacaa cgtttgagaa agaaaagact acaacacaag tagaagctac tattgttgaa
   121021 tgtatcagtg aatacatgaa taaccttaag ggaaaaaaag taaaaggtta tgaaattcat
   121081 atgggaatta caaagcgagg taatgatgta agaagtttag atttaataac taaaaaactt
   121141 gataaagaag tgaattatac tgagggaagt gtaaataaag aggggaatgt aattgggact
   121201 tatcttcatg gaatatttga tgaaataagc tttacaagag caattttaaa caatataaga
   121261 aagaaaaaag gtttaggaga attagaaagc aaagtaaact cttttaatga atttaaggat
   121321 aaagagtatg ataagttggc tgatttttta agagaacatt tagatataga gaaaatatat
   121381 gagattatga aataatgatg acttttattt ataatttagg taggaggtgt attatgaaaa
   121441 aaattttaat tgcgggtact aatagtggag taggtaaaac aacaatatca ttaggaataa
   121501 tgcaagcttt ggttaagaga aatatgaaag tacagccata taaagtaggg ccagactata
   121561 tagacccttc atatcacact tttataactg gaagacattc tagaaattta gattcttata
   121621 tgttagatga tgaaaaaata aagtatatag taaataagtc ctcaaaagat gcagatattt
   121681 cagtaataga aggtgttatg ggcttatatg atggctttgg aatagattta gataattgta
   121741 caagttcaca tacttcaaag gtattaaagt cacctgttat attagttata aatggtaaat
   121801 ctatggcagc atctagtgct gctatggtac ttggatataa ggaactagat aaagatgtaa
   121861 atataaaggg tgttatagta aataatgtaa agactaatag ccattatcaa ataattaaga
   121921 gttctataga aaaatattgt aatgttgaag tattggggta ttttcctcca aataacaaat
   121981 tctctttgga atctcgacat ctaggattag ttcctagtgt agaaatgaaa tcactaaggg
   122041 aaaaatttta taccttagca gatgaaattg aacactatat agatattgac agaataattg
   122101 aaatatcaga aagcgatgaa tttgagagtg attttgattt tcaaacttta atagaaaata
   122161 ataaaataaa agaacatgtt aataataaat caatagctat agcatatgat aaagcattca
   122221 atttttatta tagagaaaat atagagcttt tagaggaact tggtttagaa ataaactatt
   122281 ttagccctct tgaagatgta tcagtgccaa atgcagatta tatttatatt ggaggaggtt
   122341 ttccagaaat atttggaaaa gaattagaag caaatgagtc aatgagaact tccatattag
   122401 aagcacataa caataatata cctatttatg cagaatgtgg aggactgatg tacctaggtg
   122461 agaaactatt gaatcaagaa gaacaagaat ttaatatggt tggaatattt agtggaatta
   122521 gtaagatgac atcttcttta aagagatttg ggtactgtat tggtgtagcc aaggaaaata
   122581 ctcttttatc taaaaaaggg gaatctatta aagggcatga gtttcatcat tcaatatttg
   122641 aaagtgatga aaaatgtgta tattcaatga gaaaagaaag agatggaaat atagtagaag
   122701 agtgggatgg tggttatagt aaaggaaaca ctttggctac atatcttcat actcattttt
   122761 ataataactt aaattgtata gaaaattttt tgaaaaaagg aaatgaataa atgagtattt
   122821 tatctattta tataggatat gtgacagact taattgtagg agacccatat tcttttcctc
   122881 atccagtgag atttattggt aaacttataa attttactca aggtataata agaaaggtct
   122941 ctaaaaatga taggcagtta aaattggggg gatttatatt atggtttata accgttggaa
   123001 taacatattt aacaacttat gctatagtga agttatttag ttttaatata ttattgagta
   123061 ttgtagtgaa tagttttata atttatacaa cactagccac aaaatgttta aaagacgaag
   123121 cattaaaaat ttataatgta ttaaaaactg aagatataga aaaatctagg attcagctat
   123181 cttatatagt aggtagggat actactaatt taagtgaacc tgaaataata agagcaactg
   123241 tagaaactgt tgcagaaaat actgtagatg gtataattgc gcctatgttt tatgcattta
   123301 ttggaggagc accacttgct atggcctata aagctatcaa tacattggac tcaacagttg
   123361 gatataaaaa taaaaagtat aaagatattg gttttgcatc tgctaagatt gatgatatag
   123421 ccaattatat accagctaga atatctgtca ttcttatgac aattggaagt ttctttttaa
   123481 attataacta taggaactgt tttaaaatct ctattagaga tagaaagaat cataaaagtc
   123541 caaattgtgc tttttcagaa ggtgcagtat ctggtgctct aggaatacaa ctaggaggta
   123601 ccaacgttta ttttggggaa aaagtatata agccaacaat aggggataag cttagggaga
   123661 tagataaaga agatataatt aaaactaata aaattatgta tgcatcttca tttgtatcta
   123721 tgttggtatt tacactaata tatgtgttat gtaggatgat tttaattaac ttaattatat
   123781 aaattattgt ttgttaactt aagggggaca tagatgaagg atttagggca tggtgccaat
   123841 gtagatgaaa tggcaagatt atatgggaaa aacccaaaag aaataattga ttttagttca
   123901 aacataaatc caaatgtatt accaaattta gagagataca ttttaaaagg attagaagag
   123961 tgtaggaatt atccagatat aaattataca aacttgagag aaaatatatc aaaatatata
   124021 gatataaatc cagactttat aatacctggc aatggtgcaa cagaagtgat ttatttgctt
   124081 atgaagagta ttaaaaaaaa attggctata ataaatccga ctttttcaga gtatagaaga
   124141 agtgctgagt taaataattt agatattata gatttagagt tagatttaga aaataacttt
   124201 aaacttaata tagatataat aaaagaaaat ataaaaagat ttgatagttt atttatatgt
   124261 aatcctaata atccgagtgg taatgtccaa gatttaaagg aacttgttca tttactagat
   124321 aaacataata aggtattaat aattgatgaa actttcatgg aatttgttga agatgaaagt
   124381 aaatatagtt tggttaaata tatagaatca aataaaaata tatttataat taaagctgtg
   124441 actaagtttt ttggtatgcc tggtttaagg ctaggatatg gtcttacaag caacactgaa
   124501 attatgaaca aaatttatga acacaaagag ccatggacta tcaattcttt tgcagatata
   124561 ctatccaatt ttatttttga agataaagag tatattaaaa atagtaaaga atattacata
   124621 gaagaaagaa aatatatgtt acaagagttg agaaacataa gaaatataaa ggtctatgat
   124681 acagatgcta attttatctt gataagaata tataaaaaaa caactaaaga attgaaaaaa
   124741 gatttgttta agcaaggaaa catattagtt agagatgcat ctaattttat aggattagat
   124801 gatagtttta taagagtggc tataaaatct catgaagata acaaaattct tatagaaaat
   124861 atgaaaaatt tattgggtga ttaaaatgaa atcttatgga atatgcccag catcttgtgg
   124921 agaatttgta caaggtataa ttgatgatga agaatattta tgttcatatg caatagatat
   124981 gtattctaaa gtgtatattg aagaaaaatt agtagatata aatttaggga gatataagtc
   125041 aaggttagca attgaaaagg tatttgaaaa atttaattta cctaaaaaat atactaaaaa
   125101 tatttcttta aatataaata gtaaaatacc tgttggaaaa ggaatggcaa gttcaactgc
   125161 tgatatagga gctactataa aggcaacatt atcattgata gataaagatt taagtagtga
   125221 ggagatttct aaattagcag cagaaataga accaacagat tctatattta tagataaaaa
   125281 tagtatattt aatcctctaa atggaactgt tataaaatac ctaggaaatc tgaccaatgc
   125341 gaaagttgta atacttgaac caaacaaagt actagatact atgaaaatta gattgaggca
   125401 agattataat aaattaaaag tagaaaataa agaagtaata aaaaaatcat ttgctctttt
   125461 agaagaagga ttgaaaaaaa ataatttatc tctagttgga gaggcttgta ctttgagtag
   125521 cttagcaaat gagaatatag aaaaaaaaga gtatttaaat gaaataataa aaatatcaaa
   125581 aaaatatgga gcatatggag taaatattgc tcacagtgga actgtagtag gtattttaat
   125641 tgataagtct atgaatgata aaaagatgat agatgcctta tgtgaatcta acataaattc
   125701 tgtctataat aaaatttata cacaaaacat aattaatgga ggaattaagg gggaaataga
   125761 atggaataca taaagaatcc tatgaaaata gaagaaaaaa gttttgaatt gatacaagaa
   125821 ataatagacg aaattagacc agattataaa tttaagaata atatcgaaga aaaaataata
   125881 aaaagagcta tacatactac tgctgatttt gattacttag atatattaaa aatatcagaa
   125941 gaagcagttg atagtataat agatgcatta aaaaataatg caagtattta tactgataca
   126001 aatatggctc ttagtggtat aaataaaaga aagttagaat cattaggatg taagtataaa
   126061 tgtttagtgg cagatgatga aactgtaaaa ttagctaaag aaaaaggaat tactcgttct
   126121 atggcagcag tagaaattgc agctaaagaa gaaggaagaa aaatattcgt tttaggtaat
   126181 gctccaacag ctttatataa agttatggag atgaaatcag aaggtagatt agatttagat
   126241 gcagttatag gagttcctgt aggttttgta ggagcacaag aatcaaaaga tgaagttgaa
   126301 aaaacagata taccatatat aatttctaaa ggtagaaaag gtggcagtaa tttagcagca
   126361 gcaatagtaa atgctatatt atatactatg taggtaccta tatggaagaa tatgtatata
   126421 tagatggaaa aaaatataga agaggatata ctacaggttc atgtgcaaca ggtgcatcta
   126481 aggctgctgt atatatgttg attacaaaaa atagaatcaa tactataaat atagatactc
   126541 ctaaggggat accattacta ctaaaagttg ataatataaa tatttctgat acatttgtgg
   126601 aatgttccat aaaaaaagat ggtggagatg atatagatgc aactcatacc atggatattt
   126661 atgcaagagc tgaaattgta gctaaaaatg ataagaacaa agggtatctt actctaaagg
   126721 atatagatag tttaagcacc aatagtgagt gtaaaagtga gctctataag tttattaggg
   126781 tttatggcgg aactggtatt ggtgtggtta cgaaaaaagg gcttagtgtg gatgttggta
   126841 agcctgctat aaatccgact ccacttaaaa tgataaatca tgaaataaga aagcttatag
   126901 gagataattt tgaatctata cttggaaatg ataaagtttt aaaaataaca atctttgctc
   126961 cacaaggaga aactgtagca aaaaaaacat ttaatccaag attaggtata gttggaggaa
   127021 tatctataat aggtacaact gggattgttg aacctatgag tgatgagggt tggaagaagt
   127081 ctctatctat agaacttcag atgaaaaaag aacaaggctt agataaaata atattggttc
   127141 caggaaatca tggagaacag tttataagag aaaaattaaa cttagatatt aagtatgtag
   127201 ttagggtaag taattttata ggctatatga ttaaagaagc tcaaagaata ggatataaga
   127261 aaatcttaat ggcaggtcat ataggtaaat ttataaaagt atctgctggt atttttaata
   127321 ctcatagtaa ggtagcagat gctagaagtg agatattagt ggcaaactta gctttaatgg
   127381 gagctagata cgaattttta aataaaataa atcaatgcgt aactactgaa gaagctgtag
   127441 agctaataaa taatagtgaa tatagagaag tatataatat attaagtaat aaatgtaggg
   127501 agagagtaaa gcaatacttg aatgaagatt cagatgatat tgatgtggaa gtaatcatat
   127561 tttcaatgga taagtcttta ttaggtaaat cggataatac agatgattta gtggaggtct
   127621 ttatatgata aacataatag gtctaggacc tggcaactta gactatataa caaaaaaagg
   127681 tgaaaattta atttccactt ctgatgtatt aattggtggt aaaagaaatt tagagtctat
   127741 aaaaaatttt gaaggagaaa aaatagttct ggattctaat ttaagagaaa ttatagagta
   127801 cataaataac aataaagaaa agcaaatatc aataatagca tctggggacc cattaatata
   127861 tgggataggt agatatctat ctaaaaatat tgataataag atgttaaaca tggtttctgg
   127921 gattagttca ttacagtaca tattttcaaa aatatatgta gatatgaatg atgtatatat
   127981 tacaagtagt catggcaaag taccagattt tgattacata ttatcacata aaaaagtatg
   128041 tatggttaca gattcaaaga taggaccaaa acaaataagt agagaaataa tagatagaaa
   128101 tctaaataaa attattgttg taggagaaaa tctgtcatat gacaatgaaa aaataacaat
   128161 agcaaaacca gaagagataa taagaataga caattttgat atgaatgttg tggtgatttt
   128221 agatgaggaa tagtgagttt ataacaggta aagttccaat tactaaggaa gaggttagag
   128281 caatatcaat aagtaagtta aatttagtaa atgctaaaaa cctcatagac ataggggctg
   128341 gtacaggaag tgtaagtgtt gaagctgcat ataattatcc taatttaaag gttatatcta
   128401 tagagaaaaa tgatgatgct atagagctta tagagaaaaa taaaaaaaaa ttcaacttaa
   128461 aaaatataga agtgataaaa ggatatgctc caattaatct agggttaaat gttaaagttg
   128521 agtctatttt tcttggggga acaggaaata atctggaaga aataatagaa tggtctaaaa
   128581 aaaatctcgt tacaggagga agacttgtag ctaattttat aataatagat acatttaatc
   128641 aaactttaaa actgcttaaa aagcatggat ttaaagaaat agatgtatgt gttttgaatg
   128701 tttctaaact agagaaacta ggaaaaggtg aatattttaa accactaaat cctatatata
   128761 taatatcttg tgaaaaaggg gaaaatgatg atgaataaag tacattttgt aggagcagga
   128821 cctggagata aagagctgat aacattaaaa ggatacaaat tattaagtaa tgcagatgta
   128881 gtgatatatg caggttcact tgttaatcct gaacttttgg aatactgtaa agaagattgc
   128941 caaatacata atagtgcaca tatggattta caagagataa tagatgttat gagagaaggt
   129001 atagaaaata ataaatctgt tgtaagactg caaacaggtg atttttctat atatggttca
   129061 attagagaac aagtggaaga tttaaataaa ttgaatatag attatgactg tactccagga
   129121 gtaagttctt ttttaggagc agcatcatct ttaggggttg aatatacagt tccagaaatt
   129181 tctcaaagtg taattataac aagaatggaa ggcagaactc cggttccaga gaaagaatca
   129241 atacaatcat atgctaagca tcagacatct atggtaatat ttttatctgt tcaagaaatt
   129301 gagaaagttg tgtctaaatt actggaaggt ggatatccaa aagatactcc tatagcagtt
   129361 atatacaaag caacttgggc agatgaaaaa atagttaaag gaactttaag tgatatagct
   129421 gtaaaagtta aagaaaacaa cataaataag actgctttaa taatggttgg gagattttta
   129481 ggagaagagt ataataattc aaagttatat gataaggatt tcaaacatga atatagaggg
   129541 taatattgct ataatctgta ttacagaaaa tggaaaaaaa ttagctctaa agataaattc
   129601 tctagtaaat aactgtgtta tatatcaagt aaaaaataaa aaaagtaatt tagttgttga
   129661 agaaacatgt gtacatacag ttcaaaagaa gttaagtgat tttgtaggag aaatatttag
   129721 caaatttgat tacatagtat ttataatggc tacaggtata gttgtacgaa gtatagcacc
   129781 atacataata agtaagttta gtgaccctgc aattttggta atggatgaaa aaggcaaaaa
   129841 cgtaataagt ttattgagtg gtcatattgg aggggcaaac agcttgacac agtacataag
   129901 tagtcttatt gatgctaatc cagtaataac aacagctact gatataaatc aaaaagcttc
   129961 cttagatatg atagcaaaaa aactaaatgc acatattgat aattttagag aaagtgtaaa
   130021 agaagtaaat tctatgctag tgaataataa atgtgttgga ttatatattg atgaaggata
   130081 tcaagttgat actaggggat ttaaacttat agaaagtaag gatgagttaa gagatagttt
   130141 ttcaaacaca tatatagaaa aattagttgt agtaagcaat aaaataaatt gtattgaaga
   130201 tattgagaat ttaaacctag ataataaatt tgaacattgc tatagtacca aaaaaataat
   130261 aaaggtaatt ccaagagata tagtgatagg aattggctgt agaagaaaca cagatagtga
   130321 gctgatgtat aattcacttg aagagtttct taataaacaa aatatagata ttagagcaat
   130381 aaacacagtt ggaagtatag aactgaaaaa agacgaaaaa gcaataattg aattatcaaa
   130441 aatattgaag gtgccattta aaacattttc agtagatgaa atatctaagg ttgataatct
   130501 ttttgataaa tctgattttg ttaaaaaaaa tgtgggcgtg tattcagtag cagaacctgt
   130561 agcatatctt ttgagcaaag gtaatttgtt agttgaaaaa cataaatata aaggaataac
   130621 tttttcagtg gggagaataa aaatatgata tacgttgtag gaattggacc aggaagtaaa
   130681 gatacaatga ctttagaagc aataaaagca atagaagatt ctgaggctat tgttggatat
   130741 aagacttata taaaactaat agaagaattt atacaagata aagaaataat ccaaaatggt
   130801 atgaggcaag aagttgatag atgtaaacaa gcagtagagg aagcaaaaaa aggaaaaaaa
   130861 gtagcagttg taagtagtgg tgatgctgga atatatggga tggcaggtct tattttagaa
   130921 ttaatatcta aagaagatga agatataaaa gtaaaggtaa ttccaggtgt tactgcaagt
   130981 attggtgcag cagctatact tggagctcct attatgcatg atttctgtca tataagtttg
   131041 agtgatttaa tgactccgtg ggaagtaatt gaaaaaagat tgagattggc tgctgaagcc
   131101 gattttgtaa tttgtttgta taatccaaga agtaagggaa gaagtgaaca tctaagcaaa
   131161 gcatttaaaa taatgggtga gtttaaaagt ggagatacac ctgttggagt ggtaaaagat
   131221 gtaggtagag aaaaagaaga aaagcttgta tgtacttttg aaaatatgga ctttgaaaaa
   131281 gtcgatatga ctacaatggt tataatagga aataagtcta cctatattaa tggtgaattg
   131341 atgataactc caagaggtta tacagtatga ttttaatttt aggaggaact tcagatagtt
   131401 tatctatatg tgataagata aatgaactga aaaatcaacc atatatcctt tcagttacta
   131461 cagattatgg aagggaactt gcacaacaac atgcagagaa tgtaatttta ggtaagcttg
   131521 gaaaagaaga tatgctaaaa tttataaaag ataataatat agtaaaaata atagatgcca
   131581 ctcatcctta tgcagttgaa gtatccaaaa ctgctattac ttgtgcaaaa ctattgaata
   131641 tagattatat aaggtttgag agaaaatctt taattgaaga aatagattat gataataaat
   131701 ttatagtaga tacaattgaa gaagcctgtg aaatagcaaa taaaataggg acaaatatat
   131761 tcataggaac aggaagtaaa aatttgaaca gatttataga ggaaataagt gataaaaatt
   131821 tagttgttag agttcttcca acgagtgaag tcatattaag ttgtgaaaaa ttaggtttaa
   131881 gtgcagataa tatagtagct atgaaaggtc catttagcca gtatataaat gaagaaacat
   131941 ataaacatta caatatagat ttagtcataa caaaagaaag tggaatagct ggtgggttct
   132001 tagagaaggt aaatgcatgt aaaactttca atataccagt aataattata aaaagagaat
   132061 cgattaacta cgaaaatgta tttaatgaca taaataaaat taaagacata cttgtgtaat
   132121 ttttaggagg agaatatatg aagaaagcct tattagtagt gagttttggt acaagctatc
   132181 atgaaacgag agaaaagaca atagatatat gtgaagataa aataaaaaat tcgttaaaaa
   132241 gccatgattt ttttagagct tatacatcaa atatgataat aaataaaata aaaaaaaggg
   132301 atggaataga aatagataat ccaatacagg ctttagataa aatatatgaa caaggatatg
   132361 atgaagtaat aatccaaaca cttcatatta tatgtggcga agaatttaac aaattaaaag
   132421 aacaagtaga tggatattct tctaaattca aaaagattgt attaggaaga cctttgctta
   132481 cacatattga agattatcag gaagctgtag aggcaattaa gcatcaaatt cctcatatgg
   132541 aaagtaatga agcagtagta tttatgggac atggaacact tcatgaatca cattcagcgt
   132601 atccagcatt ggaatacatg cttagggata atggaataaa tgcttatgtt ggtacagttg
   132661 aagggtatcc agaaatagaa catgtaataa gaagattaaa agaaggaaat ataaaaactg
   132721 taaatttgat gccatttatg ttagttgcag gagaccatgc tataaatgat atggcaggag
   132781 atgaagaaga ttcttggaaa acaatattag aagaaaatgg atttaacgta agagttcatt
   132841 taaaaggact aggagaaaat tcttatatac aagataaatt tgttcgtcat gctgtaaaat
   132901 gtgcagagaa tgcgaagttc tatggtatag gagcaggacc aggagatggt tctttactta
   132961 cgataaaagc ggttaatact ttaaagaaac tggatattct atacactcca gaatcaaaaa
   133021 agggtggaga tagtctagct ttatcaatag ttagtgaata tttacctgaa tcagtggaaa
   133081 taaagtctag gcatttccca atgagttttg atgggaatga aaaaagttta gcttgggata
   133141 atgtggcaca agaaattata tcagatgtta atgatggtaa aaatgtagga tttgttacat
   133201 taggagaccc tatgatttat agtacatatg tatatataat gaaaagaata ttaggagagg
   133261 tagaagtcga aactatacca ggaatttcat cattttccaa tatagcatct aatcagaatt
   133321 ttccattagt catggataaa gaagctttag tggtaattcc ttgtactatg gaagatgata
   133381 agatagagta tgctttgcaa aattataatt caatagtatt gatgaaagta tataaaaatt
   133441 ttaaagaaat aataaaaaaa ttagaaaagt atgatttaat agaacatgct attttagtaa
   133501 gtaattcttc ccaagaaagc gaaaatgtgt ttacagattt aaaagaagcg caccttgaag
   133561 ataagatatc ttatttttct actatactag taaataaaga taataaaata aaataggtga
   133621 aagcaatatt taaaggagac ttaatatgaa tatagtggtt ggaactaggg gtagtaatct
   133681 agcgcttata caaacagaat gggtaataaa tgaattaaaa aagaagtatc cagaaattag
   133741 ttttgagatt aaaatcataa agacaaaagg agatttaatt caaaatgttt cactggataa
   133801 aataggtgat aaaggattgt ttgtcaaaga aatagagcaa caattattag atggaaaaat
   133861 agacatagca gtacatagta tgaaagatat gccttcttat ttagcagatg gactaaaatt
   133921 tgctcatacg cctaagagag aagacccaag agatgttcta atacttagag aaggatataa
   133981 aaatttagat gatttacctc atggagcagt aataggaaca ggaagtaaaa gaaggaagtt
   134041 tcaattattg aaacaaagac ctgatttaaa tatagtacaa gttagaggta atgtggaaac
   134101 taggatacga aaaataaaag atgaaaatat gcatggtatt gtgttggcag catcaggaat
   134161 aattagagct aatttgcaag ataaaataag ttcttattta cctgttgatg ttgttattcc
   134221 agcacctgcc caaggagctt tagctataga aattagaagc aatgatagta cgatagaggg
   134281 aatagtaaat tcactgaagg atgagaatac agaaatccaa atattggctg aaagaggttt
   134341 tttagatggt gtaaatggaa gttgtcatat tccaatggca gcttattgtg aaataatcca
   134401 agataaaata catcttactg gcttatatgg agattcagaa ggaaaaaaag tagtaatcaa
   134461 gtctatagat ggagatattt cttctcctag agagttaggt ttaaagttag ctaaacttgt
   134521 attgaaggag tatgagaatt atgaagggta aggtttactt agtaggggca ggaccaggtg
   134581 attataaact catgacttta aaaggtttag agtgtataag aaaatcggat gtaatagtat
   134641 atgatagatt agcaaatagt agttatttaa gagaagctaa gcctgattgt gaacttatat
   134701 atgtaggcaa ggcatcaagt aatcatattt tgccacaaga agatataaat agaattatag
   134761 cagaaaaagc taaagaagga aaaattgtaa ctcgtcttaa aggaggagac ccttatgtat
   134821 ttggcagagg gggagaagaa gcagagactt tagtagatga aggtatagaa tttgaagtgg
   134881 ttccaggtat aacttctgct ataggaggtt tatgttatgc gggtattcct ataacacata
   134941 gagaccatgc ttcgtcattt catgtaataa caggtcattt gaagggtgat gatagtggag
   135001 aattaaactg gaatgctctt gcaaataaca aaggtactct tgtgtttttg atgggaattt
   135061 caaacctaga gaaaataagt gaaaacttaa tgaaagaagg aaaagataag gatacacctg
   135121 ttgctcttat aagttgggca actagatata atcaaagagt tgttacatct acacttgaaa
   135181 atgtttatga aactgctatt aaagaagaag taaaaccgcc aactcttata gtagttggga
   135241 gtgttgtagg acttagagaa aagttgaact tctttgaaag taagccttta tttggaaaaa
   135301 gtattgctgt aactaggtct agaaatcaaa atagtgtatt ggtagaaaaa ataatggatt
   135361 taggtggaaa tcctatagaa atacctacta ttaaggtaga aaaaatacaa aataatatta
   135421 acttagaaaa tgaaataaaa aatataaata agtataatta tctaatacta actagtaaaa
   135481 atgccgtaga aatcttcttt gaaaagatat atgaaatgaa ttttgattta aggatattat
   135541 ctaatttaaa ggtatgtgct ataggttctg ctacatcaaa tgagttgaaa aaaagaggaa
   135601 ttatagcgga tatagtacca aaaaaatttg tagcagagtc actgtatgaa gagttagcgc
   135661 ctattttaaa tgatgacgat aatatactta tacctagagc agaaaatgct agagattatc
   135721 tggttgacaa acttaaggct atttgtgaag taacagaagt acatatatat agaacagtaa
   135781 tagatgagga gaaaaaaggt gagatattag atattttaaa ttctaatgac atagattata
   135841 taacatttac tagttcctca acagtaaata atcttgttga aattatagga aaagaaaata
   135901 ttaaaatatt agaaaaaata aaaacactat ctataggtcc tataactaca gagacaataa
   135961 atagtttggg aataaaattg tacaaagaat ctgctacatc tactatagat tcgttagtag
   136021 atttaattat aaaaaattaa ttttggaggc ttgaatatgt taagaagacc aagaagacta
   136081 agagcaagta aagcaatcag aaatttggta agagaaacta aggtgaatgt agaagactta
   136141 atatatccac tgtttgtagt agagggggaa aatataaaag aagaaattaa atctttacca
   136201 gatgtctatc atttatcaat agatatgcta gaagacgaaa taaaagaaat aagtgagttg
   136261 ggaattgaac atataatgtt atttggtgtt ccagatgaaa aagatgagtg tgcttcacaa
   136321 gcttttaatg ataatggaat agttcaaaag gcaattagaa aggtaaaaga aataaattca
   136381 gatataaatg taataacaga tgtctgtatg tgccaatata caagtcatgg acattgtggg
   136441 attttaactg atactggtta tgttgataat gataaatcat tggagtattt ggctaaaata
   136501 tctgtaagcc atgctaaagc aggagctgat atggttgctc catctgatat gatggatgga
   136561 agaatacaag caataagaga agctttagat gaaaatggat tagaaaatgt tggaatcatg
   136621 gcttatagtg ttaagtatgc ttcaaattat tatggacctt ttagagaggc agctcattca
   136681 gcaccatctt ttggagatag aaaaacatat caaatggacc cagcaaatag caatgaagct
   136741 ataatagaga ctgaacttga tatattggaa ggtgcagata tacttatggt taaacctgca
   136801 ttatcatatt tagatattat aagaagagtt aaagataatt ttgacttacc tctagcagct
   136861 tataatgtaa gtggagaata ctctatgctt aagtttgctg tgaaggaagg tttattaaat
   136921 gaagatgtaa ttcttgaatc aattacatct ataaaaagag caggagcaga tataataata
   136981 acttattttg ctaaagacat tgctaaactg ttgaaaaaat aaattctagt agtataaaga
   137041 atatcaaaaa gtataggaat tgtaattaac tattatacag tagttttgtt tagacattta
   137101 ttgaagaata atagaaacta atttgcaatt tctatacttt atttatgtaa ctaaataaaa
   137161 tttggaggta gaagatgcta tatcctatta atttaaaatt agatgagtta gatgtagtta
   137221 taattggtgg tggagaagtt gcatatagga aatgtaaaaa ttttttagag tttaacaaaa
   137281 atgttactat agtttctaaa caaattttaa ataaatttta tgatttaaaa ggaaatataa
   137341 aaataataaa agatgattat aaagaaatat atataaaaga tgcttctgta ataattgctg
   137401 ccacaaataa tagagagtta aatatggaaa taggattata ttgtaaagca aaaaataagc
   137461 tagtgaatgt agttgataat atagaaatat cgaactttac tgttccatca tatataaaaa
   137521 gaggagattt acttataagt gtgtctactg ggggcaagag tccttcatta tcatcaaaga
   137581 taaaaaaaga aattgaagag agatatactg aagattatga ggagtattta aatgtattag
   137641 gagatataag aaaaaaggtt ataaaaaaat acgaagataa aagtaaaaga aaagatgtgc
   137701 ttaatatgtt ggtaacactt gacctagaag aacttaagaa gtttgatata taaaaaataa
   137761 aataaaaaat gttaaaaagg tgttgacgga ttatttttaa g
//
LOCUS       DAFAZV010000004       135809 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFAZV010000004 DAFAZV010000000
VERSION     DAFAZV010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 135809)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 135809)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..135809
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.004"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            771..1973
                     /locus_tag="KOU88_000441"
     CDS             771..1973
                     /locus_tag="KOU88_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBK3210360.1"
                     /translation="MKTSILIALIEKTSLIVVLFLLITKLKIFKQIFQKEEYSFNDLV
                     CIALVFTFLAIFGTYSGINYMGSIVNTRIISIVSGGILFGPMVGITAGVFSGIHRYFM
                     DIGGITSVPCLLSSILAGVLSGFLYKRIPKQHRVMYGILVGMISESFTILLIYLISYP
                     HSLAIQIIGGIYLPLIVGQIGIGFVISIVEGIEKDKKDIEARNKAEIKALQRQINPHF
                     LFNSLNTIASFIRFSPDKARELIINLSTYLRYNLEYSDNLIDINKEIEQVKSFVEIEK
                     ARFGELLTVSYDIEDVNIKIPSLIIQPLVENAIIHGILESGRAGVVKISIKKLPYSLE
                     NTVRISIEDNGIGISEEIINNVYQDNMPENKIGLYNVHLRLKLMYGRGLNIRRIDNGT
                     LIVFYVKE"
     gene            1978..2748
                     /locus_tag="KOU88_000442"
     CDS             1978..2748
                     /locus_tag="KOU88_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210361.1"
                     /translation="MRAIIVEDEFPARKELRYFIENKSGIEVVSEFTNGIEVLDFIQE
                     NKIDVIFLDINIPHLDGMLLAKTLNQFKSRPKIVFITAYESYAVDAFSLDVFDYILKP
                     YSEERIISMLNKLEKSEMSDIELSNVNSNLYKYKKEAVNQEIEEITHKISLWKGDKLV
                     VIDIDDIYYCEANERQTFIYTEKEKFILKEGISEVENLINDKTFFRTHRSYIVNLTKV
                     KEIIPWFNNTYILKLKNSDYEVTVSRSKVKEFRLLMHI"
     gene            2894..4315
                     /locus_tag="KOU88_000443"
     CDS             2894..4315
                     /locus_tag="KOU88_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBK3210362.1"
                     /translation="MVSFLGSIVVLIVGYFVYGTFVEKVFGTNDKNQTPAIACRDGVD
                     YVPMKWKRIFLIQFLNIAGLGPIFGAIQGALFGPSAFLWIVFGTIFAGGVHDFASGYL
                     SMKNKGTSASELVGLYLGNGAKIAMRIFSVILLVLVGVVFVTGPAGLLKTLTGVNAQI
                     WVGVIILYYIMATVLPIDKLIGKIYPLFGAALLIMAVGVAGGLIIKGYNIPNINLQNM
                     NPNGTPLFPYLFITIACGAISGFHATQSPLMARCVEKESEARPVFYGSMVAEGIIALV
                     WAAAAMSYFHGIPQLNVIFNDGGAATVVNTVSVGLMGPIGGALAILGVVACPITSGDT
                     AFRSARLTIADAMNYNQDAVKNRFLIALPLFAVGVALTFIDFNIIWRYFSWANQTLAM
                     IMLWTGSAYLVKANKNHYITTLPALFMTVVTFSYIMQAKEGFRLPVNISNGIGVIVAI
                     ILGLLFFKKAKHIKQQNNHKLAS"
     gene            4581..5063
                     /locus_tag="KOU88_000444"
     CDS             4581..5063
                     /locus_tag="KOU88_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBK3210363.1"
                     /translation="MDTKKYKDKLLKERENLTNLVEDMKDNTLFGDTTKHTSEKYSSG
                     ELSSYDNHIGDMGTDLYMQNMQNSLINHEEGRLYQIDLALSKIENGTYGICDLCHNQI
                     DLERLDILPDTSLCNDCAKKENNLLGDAMQNPDVEDSNFYSEDLTNLTDLNKNGILRD
                     "
     gene            5118..5897
                     /locus_tag="KOU88_000445"
     CDS             5118..5897
                     /locus_tag="KOU88_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK3210364.1"
                     /translation="MKKIIWGICICLLSIVGVYTYNHNTHNQDSSKEAYSLNDNIKDD
                     YEDVIIKKGNEDEKILALTFDDGPDEDFTPQVLDILKKNDVKATFFVVGEKVEYNKEL
                     LKRQYDEGHEIGNHTFTHINVAKNSYSSVEKEITDTQNIIKSVIGVEPKIFRPPYRAM
                     SKSVCDIIVSKGMNIILWSNLDPRDWSNPGVDAIINTILTKVQNGNIILLHDYNTKRN
                     DKSQTIQALEVVIPKLKERGYKFVTVSELIQHLDKNKQVQK"
     gene            6207..6653
                     /gene="lspA"
                     /locus_tag="KOU88_000446"
     CDS             6207..6653
                     /gene="lspA"
                     /locus_tag="KOU88_000446"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBK3210365.1"
                     /translation="MLYILIIILLIGLDQLSKIWVLNNLVDVSTIPIINNVFHLTYVE
                     NRGAAFGLLQNNQWIFIIVALLATVFGLYYLNTRKVHIFGRLGIILIISGALGNLIDR
                     VRLGFVVDYFDFRIIWEYVFNIADVFVVVGTVFLCIYVLFFESKSR"
     gene            6622..7569
                     /locus_tag="KOU88_000447"
     CDS             6622..7569
                     /locus_tag="KOU88_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK3210366.1"
                     /translation="MFYFLKVKVGDIMDEVKEFLVLEEEEEVRLDIYLAEQLGDMSRS
                     YIQKIIKDGKVKVNNKVEKARYLVKEEDNIVIEIPEPKVLEVLPQDIPIDIVYEDDDV
                     LIINKPQDMVVHPAPGNYENTLVNGILYHCKDKLSSINGVIRPGIVHRIDKDTSGLLM
                     IAKNNYAHNFLAEQLKEHTITREYEFICYGVVKEDKITVDKPIGRNPKDRLKMAVVKD
                     GKNAITHFEVVERFDKFTHMRARLETGRTHQIRVHALFINHPLLGDYVYGPKETKFKL
                     KGQTLHAKKLGFIHPTTKEYIEFNSELPEYFKEVIKKIK"
     gene            7929..8462
                     /gene="pyrR"
                     /locus_tag="KOU88_000448"
     CDS             7929..8462
                     /gene="pyrR"
                     /locus_tag="KOU88_000448"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBK3210367.1"
                     /translation="MVEKAQLMDEKAIARAITRISHEIIERNKGVENLVLVGIKTRGV
                     PIANRISKKIEQIEGTKVDTGDIDITLYRDDLEKIHVEPVVKGTYLDFNVNDKTVVLV
                     DDVLYTGRTVRASLDAIIDIGRPKSIQLAVLVDRGHRELPIRADYVGKNVPTSRHEII
                     SVSLLEIDGEDSVTIKE"
     gene            8746..9957
                     /locus_tag="KOU88_000449"
     CDS             8746..9957
                     /locus_tag="KOU88_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBK3210368.1"
                     /translation="MKKTIMSLQHLLAMFGATVLVPILTGFNPSVAIFCAGVGTLIFH
                     FCTEGKVPAFLGSSFAFIPVILAAKEAYGGDLAYAQGGIIVAGLIYIIMSIIVKVVGV
                     NKIKLYFPAQVTGAMIVVIGLNLLPTAFSMASANFVIAFITLAIAILTNKFGRGFIKQ
                     LGILIAVFSGYIICLILRLVDITTITEASLFAIPNFTVPKFSLGAIVIISPVVLAVFM
                     EHIGDMTTNGAVVGKNFIENPGLNRTLLGDGFATIVAGCLGGPANTTYGENTAVLAIT
                     KNYDPSILRRTAIFAILLACVGKFGGFLQSIPGSVMGGISIMLFSMITYVGLKTIRDS
                     SCVESKINILIIAVILLIGLGTTYLSNKGISIGIPITSTVKITGLSLAAIVGIVLNRI
                     LNNQDFKVEEE"
     gene            10256..11908
                     /gene="abc-f"
                     /locus_tag="KOU88_000450"
     CDS             10256..11908
                     /gene="abc-f"
                     /locus_tag="KOU88_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HBK3210369.1"
                     /translation="MLLVKVENLKKYYADKLILDIDKLEILENDKIGLVGSNGQGKTT
                     LLKAILGEIEIDEGYTYLTESYSYISQSENNIETCSHSKEKSLLNAPDKFEEHLSGGE
                     KVKLKIADALSNKKNIIIADEPTSNLDKKSIGVLEDMFKRHEGALLLISHDRRFLDEL
                     CTTILELEDGKLKAYKGNYTDYLMQKDEEVKRADFEYQEYVKEKKRLEKALLYKKALS
                     DGIRKTPKRMGNSEARLHKMGGQTNKKKLDSNVKAIKSRIDKLEVKNKPKVSKEMNIK
                     MQDGMEIISKNLVEVKDMTLKLENKLLLDNVSFKIKRGKKIALLGDNGCGKSTLIKEI
                     LADKNDNIKINNKVKVGYFDQNQSLLDEEKSVLYNTKVNSSFDESFIRINLSLFGFKG
                     DDVYKKVKVLSGGEKVKIALCKIILEDNNFLVFDEPTNYLDIKSMEALEKALINTDKT
                     MLIVSHDRVFVSHICNYIIEIKDAKIREFDCNYDEYTISRNKKTPSRENRIKKENLLV
                     LENRLTTVISMLSIEKDNLKKELYESEYNELLKQINKLKNSF"
     gene            complement(12123..13898)
                     /locus_tag="KOU88_000451"
     CDS             complement(12123..13898)
                     /locus_tag="KOU88_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HBK3210370.1"
                     /translation="MALDGLVIHSIVDELSSKLTGGKIDKIHQPEDDEVIFNIRNNKE
                     NFRLVLSASASNPRVYLTSNYQKENPLKAPMFCMLLRKYIQGGNIVEISQIGFERIIK
                     ISVESLDELKEKTVKNIMIEIMGRHSNIIITHGEENKIIDSIKRVPFSISRVRQVLPG
                     HDYSLPPEQNKLNPLDDISKDLFIKNLEELEGPIFKSIYSKFLGISPIIAKEICYRAG
                     VNQNAIIKDISDEQFDSLHKVFCNLFNDINSNKYSPCIIIDKKVDKVVDFSCINLTLF
                     SDLSYINKDSMSRILEDFYRTKDIKDRINQRSSDLKKSISVKLDRLYNKLKKQEEELS
                     ESENADIYKIKGELITSYIYMVEKGMESIEVANFYDENCNDVTIELNKNLTPSENAQK
                     YFKKYNKMKHAKVEISHQISLNKEEIDYLENIILSIENCENLAELQDIKEELAKVGYI
                     KTQKKNSKKDTIPSTKPHEFVSSDGFKILVGKNNKQNDYLTLRLADNDDLWMHTKNIP
                     GSHVIIKCAGKEVPDNTVFEGAMLAAFFSKSKLSSQVPVDYTKRKNVKKPSGSKPGMV
                     IYETNSTIYVTPEEETVAKLKVKSE"
     gene            14194..15228
                     /gene="ltaE"
                     /locus_tag="KOU88_000452"
     CDS             14194..15228
                     /gene="ltaE"
                     /locus_tag="KOU88_000452"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBK3210371.1"
                     /translation="MRFIDLRSDTVTMPTDEMREAMAKAPVGDSIFRDDPTVNKLEEL
                     AAAKVGKEDAIFLPSGTFGNQLALFTHCLRGQEIIIGKGYHIVTHEVGAPAVIAGVQL
                     RTIDEDESGALNPELVEKAIRRDDIHEPQTGLICVENAYSGGTVVSLDNLREIKKIAE
                     KHNLPVHLDGARLFNAALNLGVEAKEIAKCCDSVMFCVSKGLAAPMGSILAGSKEFIA
                     KARRKQKVMGGGMRQVGIVAAAGIIAIEKMTLRLNEDHENAKYLACELNKIDGIEVNN
                     VNPDISMVFFKMSEDIIKEDVLIKEFFERNIKINKMENGEYRFVTHVDITKEDLDYVL
                     KTLKELIGVC"
     gene            15515..16345
                     /locus_tag="KOU88_000453"
     CDS             15515..16345
                     /locus_tag="KOU88_000453"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBK3210372.1"
                     /translation="MKFWKLHGIGNDFIAIDGRFDQINPSDYTALAKKVCHRRFSVGA
                     DGLLVVKDSKVADVEMVYYNSDGSRAAMCGNGLRCFCKFVYDNCIVKKESFTVDTLDG
                     IKDIKVNLTNREINSIRVNMGKGSFIAKDVPVLTNKERFVQESIKVLDRELKVTSMLM
                     GVPHTVVIVDELDVDDVCKYGKEIENNKIFPEKTNVNFVKVEDKYNIHVYTWERGCGY
                     TLGCGTGMTASAIVCNLLNMVESSVNVTSQGGTVKIDVGDFSYMTGPAVKICEGILEV
                     "
     gene            16349..17230
                     /locus_tag="KOU88_000454"
     CDS             16349..17230
                     /locus_tag="KOU88_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBK3210373.1"
                     /translation="MAISMTGFGRGEYKDDNYYFLVECKTINHKYSDINIRLPRKISF
                     LEDKVRNLVKNYVKRGRVDLYIKFDLLGKEDVNLNFDEGLASQYIDILKEIKNKFDII
                     DDISVMNVAKFPDIVKIEEKEEDEDLLWSMLNQAVEDALIKLREMRSEEGKKLAEDIA
                     MRCDLLKNHIEEIEKYSSSVVEDYREKLNLRISELLDDPSIIDENRLAQEVAIYADKS
                     SITEEIVRFKSHIGQLKNTIFKDDSIGRKIDFLIQEMNRETNTIGSKSSDINITNLVV
                     EVKSELEKIREQIQNIE"
     gene            17260..17877
                     /gene="gmk"
                     /locus_tag="KOU88_000455"
     CDS             17260..17877
                     /gene="gmk"
                     /locus_tag="KOU88_000455"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBK3210374.1"
                     /translation="MFVKKGLLLVVSGPSGAGKGTICKELLKENDTIKLSVSATTRKP
                     RTGEVDGVNYFFISKEKFEEMIEKGEFLEYAQIYDNFYGTPKAAIMECLEKGQDVLLE
                     IEMQGAKQIKEVCPEGVFIFVLPPSLKELKNRIVGRGTETEAEIEKRFSCAYEEIKMI
                     KDYDYFIFNEDVKTSAKEIEGIISSEKNKVSRYKNIIIEKFKEEL"
     gene            17880..18146
                     /locus_tag="KOU88_000456"
     CDS             17880..18146
                     /locus_tag="KOU88_000456"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBK3210375.1"
                     /translation="MLKPSINEVLEKIDNRYYLVGTVSKRARKLIDGEEPYVSNKTKE
                     KPVCVATKEVASGKITYRLLTEEEIEIEEARHHAEQHQQISEEE"
     gene            18151..19350
                     /gene="coaBC"
                     /locus_tag="KOU88_000457"
     CDS             18151..19350
                     /gene="coaBC"
                     /locus_tag="KOU88_000457"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBK3210376.1"
                     /translation="MLKDKTVVIGISGGIAAYKACDVVSKLKKLNANIHVIMTKSATE
                     FVKPLTFQSLSQNYVVEDMFEEPKTWEVEHISLAKKADLFLIVPASANVIGKIANGIA
                     DDMLTTTVMATKAQVLIAPAMNTNMYENPIVQKNIQTLKSFGYKFIEPESGRLACGDI
                     GTGKLANPDIIVEEVLTNLTKEQDLKGQSMIVTAGPTVESIDPVRYLTNRSSGKMGYS
                     IAREAIARGADVTLISGPTNLSIPQNLKKFVQIESAQDLYEAVVSNLSENKIVIQSAA
                     VADYKPKTYSDKKIKKKNDDLSIELSRNYDIAYEIGKIKEDKILIGFAAETNDLIEHA
                     KGKIKKKNLDFIVANDLTKEGAGFRADTNIVKIIDVEGNITEYPKMKKEEVANVILDK
                     VKALLEK"
     gene            19589..22114
                     /gene="priA"
                     /locus_tag="KOU88_000458"
     CDS             19589..22114
                     /gene="priA"
                     /locus_tag="KOU88_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBK3210377.1"
                     /translation="MNNILNLSRGFIMKKYAKVIVRSNTIYTDNLFTYQIPVFLSDVI
                     KIGHRILVRFGKGNKPTEAFVFQFTDSLDEKIKIKEIIDILDENPIFRKEDLELVYWM
                     KNRYLCTYIECINLIYPKGYKLNNYKVVLLGESLSGLNDIELKEKISTLSDKNREIVE
                     KVIDSKGKIKVDKLKYIPNLNSSLYTMNKNGIIKLCWEYKNHKNEKKVCYISLSLESD
                     KIDDYIEQNKINVGSKQKEILSFLKNNENVEINDLLDLLNASKQSINSLSKKKLITLE
                     FKDYYREPKSIYKSVLKSIKLNNEQQEAVDEIKSNMFVDDKKPYLIHGVTGSGKTEVY
                     MEIIEFALNQGLDSIFLVPEIALTPQTIDRLKSRFGDLVGVFHSKLSEGEKHDVYKAV
                     KAGKVRVLIGARSALFAPFNSLGLIIIDECHESSYKSEKNPKFNAIEVARFMALKNNI
                     TLILGSATPSIEEYYRAKSGEYKLINIKSRANDKPLPNIEVVDMKDELDKGNRSIFSL
                     KLQKEIRYAIEENNQVILFLNRRGYANFVSCRKCGYVFQCENCDISLTYHKKSNTGRC
                     HYCGYEKEIPKECPECKSTYVKPFGVGTQKIEEELKYIFPDIKTLRMDKDTTSKKGAL
                     DEILNKFKDKEADVLIGTQMLSKGLDFENVTLVGILSADMILNFPDFKSFETTFQLIT
                     QVSGRAGRADKEGKVVLQTYDTEHYAIKHAIEYDYEGFYEDEIKIRKAFGYSPFNNML
                     SVVVSGEDERLVIKNIKNMHASLIYLLEKRGINDLGFILGPNPCSISKINQNYRWQIL
                     FKDENIEINLLKGIIKYICITKRDLIFDKNINVSIDINPNSVL"
     gene            22132..22572
                     /gene="def"
                     /locus_tag="KOU88_000459"
     CDS             22132..22572
                     /gene="def"
                     /locus_tag="KOU88_000459"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBK3210378.1"
                     /translation="MALRQIVQIGEPVLRKKSKKVEKIDEKIIQLLDDMAETMYDADG
                     VGLAAPQVGILKRVVVIDIGEDLIELINPEIIETSGEQIDEEGCLSVVGEAGNVRRPN
                     YVKVRALNRNGETIELEGEELLARAFCHEIDHLDGILFVDKIEK"
     gene            22587..23516
                     /locus_tag="KOU88_000460"
     CDS             22587..23516
                     /locus_tag="KOU88_000460"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBK3210379.1"
                     /translation="MKIVFMGTPDIAVPCLQKIIDEKYEILGVVTQPDKPKGRGKKLG
                     MSPVKELAIENNIPVYQPVKARDKEFIDKIKSLNPDVIVVVAFGQILPKEILEIPKLG
                     CINVHVSLLPKYRGAAPINWVIINGEEKTGVTTMYMDEGLDTGDMILKTEVNLDENIT
                     AGELHDKMMNIGAETLKETLRLIEEGNAPREVQNHEEFSYAPIMNKSLGNIDFSKSAR
                     EIHNLVRGVNPWPSAYTTYNDVIMKVWKTKVLDEKSTKDVGTIIDVSKDGIKVSTIDN
                     VLLIEEIQMPNKKRMLVGEYIKGNTIETGLVLG"
     gene            23526..24278
                     /locus_tag="KOU88_000461"
     CDS             23526..24278
                     /locus_tag="KOU88_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF116 domain-containing protein"
                     /protein_id="HBK3210380.1"
                     /translation="MTDIKKYLTSVGILILILGILIGVVNFFIISLTQIFSLMINIII
                     ISLILIILCSTAVTYRVIKGKYVNSNIMKINFNIVSGLFPIISFIASSFGMSKSDIRR
                     IYIKLNNEYIYSNKYNFNPEDIIILIPHCIQENSCKLKVTNDIDNCKECGRCNIGELI
                     KLKEKTNVKIFVATGGTLARKIIMDTKPKAVVAVACERDLTSGIQDIKKIPVLGVFNK
                     RPNGPCVNTNVDMMDIEKAIGFLTGKNILVCN"
     gene            24347..25048
                     /locus_tag="KOU88_000462"
     CDS             24347..25048
                     /locus_tag="KOU88_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBK3210381.1"
                     /translation="MYPVYGGFWGFDPTMVVLIPAILLTIYAQFKVSSTTNKYLRVNT
                     RRGYTGEQTARRVLDSNGLYDVKIEMVRGHLSDHYDPRRKAVRLSEDVYYGTSITSVA
                     VAAHECGHAIQHAKGYAPLQIRSSLVPVVNFASSISWFLIFLGFIMAGPFLKIGILLF
                     SASVLFQIITLPVEFNASSRAIVQLGNLGIIDESESRQSRRVLSAAALTYVAAALVSI
                     LQLLRLLLIAQRRND"
     gene            25110..26435
                     /gene="rsmB"
                     /locus_tag="KOU88_000463"
     CDS             25110..26435
                     /gene="rsmB"
                     /locus_tag="KOU88_000463"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBK3210382.1"
                     /translation="MDAREVGFKVLCDIEKNDNYSNIAINKHFKNLEISDMDRGLATE
                     LIYGVIENKYYLDYIINKLSKIKVKKMSTYVKIFLRMGTYQILFLDSISDYAAVNETV
                     KLSKKYDKKSSGFINAILRNEIRAKETIMDITEEDSVKYLSIKYSYNSWIIKNWIDKF
                     GQEFAEDLLEANNEKPSIYIRTNTLKISREELIEKLSEMGIVCLKVPMVEEAIKVEKM
                     KNIEKNELFKAGLFTIQDISSMIVGKVINPKEGSFILDVCSAPGGKSTHLATLMNNTG
                     QVVARDIFEHKLKLINSTVNRLGLKNVFVERFDASEIDENSISKFDYVLADVPCSGFG
                     IIRRKPEIKYKKEEELKDITSIQKKILENASKYVKVGGTLVYSTCTIQGVENINIVTS
                     FVEENHNFEFVPIDTVNVDLDNQDKGYLKIYPNIHGIDGFFIAKLKRIR"
     gene            26443..27474
                     /gene="rlmN"
                     /locus_tag="KOU88_000464"
     CDS             26443..27474
                     /gene="rlmN"
                     /locus_tag="KOU88_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBK3210383.1"
                     /translation="MEKKKIVLKNFTEDELKEFMKTIDEKPFRGSQIFSWIYKGAKTF
                     DDMNNIPKSLRNKLEEVSCIGHIDIELKLESKVDNTKKYLFLLDDGNIIETVMMDYDS
                     RVTVCVSNQVGCRMGCNFCASTMDGLIRNLEPWEILDQVIKIQEDTGKRVSNLVLMGS
                     GEPLDNFENTKQFLKIINEKNGLNIGYRHITLSTCGIVPKMYELADLEIAINLALSLH
                     SPYDEERRKIMPVANAYSIEEILNACRYYIKKTNRRVTFEYSLIKGVNDSEKEAKALA
                     KLLKGMLCHVNLIPINKVEEREYEKPDKAFIYKFRDSLEKNNIPATVRMSMGSDISGA
                     CGQLRRKYK"
     gene            27494..28246
                     /locus_tag="KOU88_000465"
     CDS             27494..28246
                     /locus_tag="KOU88_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBK3210384.1"
                     /translation="MVYSCASHIGKIRKNNEDYCEGEVIDTEHGPIGIFAIADGMGGH
                     KKGEVASKLAVENIIDFLKENLLQHDNVKIDYIDDILKQAYNNVNSIVHKKSMEDIEF
                     EGMGTTLVTAIVYNNVLYVANVGDSRCYLLTDEKFDKITIDHSVVEELMMAHVITEEE
                     ARRHPQRNRITRAIGTDDMVVVDIFKKEIKKSDIILLATDGLTGFIDDEDIRDLILDY
                     EYERTSNISEELISMANDVSGKDNVSVIVIKV"
     gene            28263..30278
                     /gene="pknB"
                     /locus_tag="KOU88_000466"
     CDS             28263..30278
                     /gene="pknB"
                     /locus_tag="KOU88_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBK3210385.1"
                     /translation="MGDTILGNRYEIIRKIGDGGMAFVYEAKDRLLNRTVALKVLRPE
                     FVDDDEFLTKFKREAEAVASLSHPNIVNVYDVGEDGKVHYIVMEFVDGKNLKEIIQDE
                     GILDEYTALDITKQIAMALSAAHKKGIIHRDIKPHNILISNEGRVVKVADFGIAKAVS
                     NSTMTNIGSIIGSVHYFSPEQAKGKFVTNNADLYSLGIVLYEMLIGKVPFRGDSPISI
                     ALQHINDDIDFTSEEKVRIPQSVRTTIKKLTEKSSADRYQTAEELIEDIEYIEKNIDL
                     DFIKEYDDFATKKIDEKEINKVVNPTLAKPAPEKVVKPVEVADLDDDEDYYDDFYEED
                     DDEDEEEEEIMRAKKNQRPKSTPSKRTKKKKKKQESPKSRRRLKVIAAVLILILCAQV
                     FLAYKFLFAGGFGNKSLTVPNLVNMTLEEAQSAVEKEGLYLSVKSEEYNSEVDENCII
                     SQTPEGGSTNVKKGDTINVVVSKGSSQASVPNVVGLTLSNAKQLIEENNLKVGTVKYE
                     YSSIYKEGTVLSQSPGAGSSRAQEGDEVNLYVSKGSEKSNTQTPTVPDKKPTTPENNT
                     PTEPGSNSGNSGGNSGGSNSGNSGGNSGNNGSNSGGSNSGNSGGNSGGSNSGDNGGSS
                     GGSNSGDNGGSSGGSNSGDNGDSSGGSNSGDNGGTSSGTGANIGKTE"
     gene            30386..31123
                     /locus_tag="KOU88_000467"
     CDS             30386..31123
                     /locus_tag="KOU88_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK3210386.1"
                     /translation="MKKKTVLITGGARGIGKAMSKAFAKEGYNVLVNFNKSENEAKEL
                     YTILNEKNFSVKLFKANISNREDVEDMVDYCIKEFGGLDVLVNNAGVSQDKLFTDITD
                     EDWDNMMNINLKGSFYCSQVALKYMISEKKGNIINISSIWGISGASCEVHYSITKAGI
                     IGMTKALAKEVGPSNIRVNSIAPGVINTDMLSGYNEEDIDALVEETPLMRLGTPEDIA
                     NCAIFLASDKSNFITGQVISPNGGFVI"
     gene            31221..32105
                     /gene="rsgA"
                     /locus_tag="KOU88_000468"
     CDS             31221..32105
                     /gene="rsgA"
                     /locus_tag="KOU88_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBK3210387.1"
                     /translation="MLEGKIIKGISGFYYVDTYNGIYECKARGIFRKQKITPLVGDRV
                     KISIVDEDEKKGILEEIDSRDTELIRPPIANVDKALIVFAIKNPKPNLSLLDRFIVLA
                     EKENLETVIILTKADLDDNDTLETVKNIYELSGYKVIPVSNITKLNIDKVKEELKENV
                     VVFAGPSGVGKSSLLNEIDENFKLQTGVVSDKIKRGKHTTRHAELLKLEFGGMVADTP
                     GFSSLVLEDIEEVELKDYFIEFDKFNDCKFGSKCIHENEPNCAIKEAVTNGEISKERY
                     DSYIQLLHEIRQNNSRRY"
     gene            32110..32781
                     /locus_tag="KOU88_000469"
     CDS             32110..32781
                     /locus_tag="KOU88_000469"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBK3210388.1"
                     /translation="MIKLAPSILSADFAKLLEDVRKVESAGCEYLHIDVMDGHFVPNI
                     TLGPLVVKSLKKENINMVFDAHLMIENPDQYIEEFVKAGCDIITVHQEACVHLHRTIQ
                     NIKSHGIKAGVVLNPATPVDTIKHVLPDLDMVLLMSVNPGFGGQSFIPCVLDKIKELK
                     AIIDSQGLNIDIEVDGGISPKNVAEVVQAGANIIVAGSAIFGSDDIQETVNLFRKNAS
                     LEELV"
     gene            32790..33431
                     /locus_tag="KOU88_000470"
     CDS             32790..33431
                     /locus_tag="KOU88_000470"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBK3210389.1"
                     /translation="MKICIVLNGEIEDYEVTRDIIIKECYDCIICADGGANHTYKMEI
                     MPDYILGDLDSVEEEKINFYKNKGVKFEKFPSKKDETDTELCLFLAKTLKANHIDFFG
                     ALGGRIDHTLANIKLLYYLKEDGIYSRILSDKEEMYIVENEEISLYGNPGDTISVIAI
                     NGDAKGVTLTGLEYPLDNYYMKYSVPIGISNVMLSNSCKIKVEQGCVLVVRNL"
     gene            33562..34191
                     /locus_tag="KOU88_000471"
     CDS             33562..34191
                     /locus_tag="KOU88_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK3210390.1"
                     /translation="MVDSIIFDLDGTLWDSTEEVCKVWQDVLSKHKEIELSVTKDLFR
                     SLMGLSFEEIANRLFPNLSEEERMNLLNECSLKECDYLSENGAKLFDDIEDTLKLLSK
                     KYKLFIVSNCQAGYIESFLKAHKLEQYFIDFECPGNTGLHKGENNKLIIERNKLINPI
                     YVGDTQGDANSAKFVGIPFIYAKYGFGNVDVYDYFIDSFKDLLEHDILK"
     gene            34246..34902
                     /locus_tag="KOU88_000472"
     CDS             34246..34902
                     /locus_tag="KOU88_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK3210391.1"
                     /translation="MELQDTIFKRQSVRKFKNQDVSDEDILKMIKAAGAAPSGKNIQN
                     WHFVVIKRRDLMEKIADVITKKQQEILAEMDKVSVDKANRFRKFVKNFTLFYLKAPVL
                     VLVFTKVYNPSGYYELELIDAPKETIDKLFIRNPGMQSLGAAIENFTLSAIELGYGSC
                     WLTSQNYAADEIEAVLEAETGFEKGEYFLGAMLALGVPEDNLKSPSKKPVEEICTFIK
                     "
     gene            35317..36033
                     /locus_tag="KOU88_000473"
     CDS             35317..36033
                     /locus_tag="KOU88_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210392.1"
                     /translation="MNSYNILVVEDEKEIADAIEIYLLNQGYNVFKGYNGLEGLKVIE
                     NQEIHLAIVDIMMPKMDGITLTMKLRENYNFPVIMLSAKSEEVDKIMGLNIGADDYVT
                     KPFKPLELLARVNSQLRRYTKYLNMVGNKEQKVESDDSVFAIGGLELNENTKEVSIDG
                     KYIKTTPIEFKILSLLMRNAGRVFSADEIYERVWNENAVNTDTVMVHVRNIREKIEID
                     PKNPKYLKVVWGVGYKIEKI"
     gene            36008..38341
                     /locus_tag="KOU88_000474"
     CDS             36008..38341
                     /locus_tag="KOU88_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK3210393.1"
                     /translation="MDTKLKKFKDKYIVTIIVFILMLSASLGMISQYSTIQASAKGGA
                     ENPFEQESFVDSIYKGSYVLYHNMKEEQEGKMIQPSKLFINEETMNYIKNVSKEKDTY
                     DGSETYYTDDSINADFNENFENWEHFIKASGKNLKYYLVDKESNFEFFNDNKELGVLD
                     TTKNDASKENSDENQSKNTEMNDEERQKQITDIKENYRFYVVMNFDKDGKVNIVDSYG
                     VNQKVINQMLLSKAREDLMDTSLGGNSISYKLSPIKNITLVYAVPKAISKGDSVEYGY
                     GNTYFDDGIISYISNVENNSYYKISGMILKIILAIVVIVALAFPYRKSKELLGFDTLS
                     RIPLEILFIALAIIQGLVDLYPTVIISNTLSGNYVEYLINNDISAKMASILVSLMNLT
                     YWFVIFSIIFVFIILLKHILNVGIREYFTKHTMTGMFFVWLKKAGKTVINQIRTINLK
                     EKPNKTIVTILGINLLIIVIMCSMWFFGIILALIYSVVLFKILSDYSKKTIYEYNQLL
                     DVTKKISDGNLDVNMEKDLGFFNPIKDELGNIQTGFKKAVDEEVKSQKMKTELISNVS
                     HDLKTPLTSIITYIDLLKDESITDENRKLYIDTLDRKSQRLQHLIEDLFEVSKANSGD
                     VYLNIVNVDIVSLMKQTLLELDDKLADSSLIVKNNFSNEKIILPLDSQRTFRVFENLI
                     INISKYAMPNSRVYIDILETDNKVNIMLKNMSASEIDFSVDDIMERFVRGDKSRNTEG
                     SGLGLAIAKSFIELQGGKMNISVDGDLFKVTITFNKN"
     gene            complement(38658..41336)
                     /gene="mngB"
                     /locus_tag="KOU88_000475"
     CDS             complement(38658..41336)
                     /gene="mngB"
                     /locus_tag="KOU88_000475"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBK3210394.1"
                     /translation="MKKTKVHVVPHSHWDREWYFTTSRSKIYLMKDFQDILDILEEKE
                     DFKYFTMDAQASLLDDYLKWRPQDEYRIRDLVQRRRLVIGPWYTQTDQLVISGESIIR
                     NLYYGIDRCNEFGEPMRVGYVPDSFGQSAQMPQIYRGFGIDSSLFWRGVSDDMVDTTE
                     FIWKGSDGSKVLAVQIPFGYYYGGNIPEDDSDLKEYLKDIIGKLKVKASTNNVYFPNG
                     FDQAPIRKNLPDILKKANEIDNENEYEISDIENYIDSVRNERNEFTELKGEFLNAKHM
                     RIHKSIFSSRSDLKIMNNKLENYITNVLEPLLTLSYSLGNEYPHLVIKDIWKLMFENA
                     AHDSIGSCNSDTTNEDVYTRYKQARDLSINLLDLHMRLISTQIKNNNEEITLTVFNGF
                     PEVRNEVVEFDTYIPGQDFVIKNKNGEILNYIIKEKEDITNYILTQTIRLNPSKKIYI
                     PKTVYRAKIALSVKDIPPMGYTQLVFELDTKNKCEIETSNCKEIENKYYKITANKNGS
                     LEILDKESNKTYKNQAVIEDNGDDGDSYNYSPPRKDIYVSSLDSVSSVEVLKSNIQEE
                     MILKYSLTIPASLEERAIGKVSVKMPVTMKITLEPKEQIIKFNVNIKNNQALSHRVRV
                     LFNTEIASKFSIADQQFGIIQRPTVLEKDLALWKRDNYSWQEKPITIEPMQSFVTLED
                     GQRGIALITGCVREYQIVGDNLDTIALTLFRSFGYMGRENLLYRPGRASGEKIIATPD
                     AQLLKELNFDFGLYIYNNKFDEANVANTAKRFLTPIQIYEYADFLNGRLIFAFNDEKQ
                     IYENEYSLMNVNNSNFTVSAIKKEEKGDGIVVRIFNGMKNEDAKGSLNINKNVNDAYS
                     AMLDEIYDNTSKLKVNTKTVEVNSLSHCKVQTIVIK"
     gene            complement(41411..42517)
                     /locus_tag="KOU88_000476"
     CDS             complement(41411..42517)
                     /locus_tag="KOU88_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBK3210395.1"
                     /translation="MSKKNKSLLSELKGHLMTGISYMLPLVIGSSLVVAIPKLTALAV
                     GITSLDAYKNVSGFYHILYLMEQVGWTGIGLLNTVLAGFIAFSIGEKPAMGAGFIGGL
                     IASNTNAGFLGAVIAGFFAGYVCKFLKKKIKISGSASGMMPLIIMPLITVGLTGFLMS
                     VVLAGPLGNINTSLNAWVAEMCQNGTNSVVLALILGAMIGFDLGGPVNKAAWMAGNAL
                     LLEGIYLPAILVNCAIVIPPLGYGLATFIRKSKFSNALAETGKGNIVMGIIGITEGAI
                     PFTLTNPLKLVPVNMIGCALGVGLSALLGVHAIMPPVGGLYGFISIGSGWAYLVGAIF
                     GALVIAILSTTLVDFNEDETTENIEFDEIELDIM"
     gene            complement(42631..42939)
                     /locus_tag="KOU88_000477"
     CDS             complement(42631..42939)
                     /locus_tag="KOU88_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBK3210396.1"
                     /translation="MKIVAITSCIAGLAHTPMAAKALEQAASKMGHEIKVEQQGAMGR
                     VNTITKEEAQDADFILIASDQTISGMERFDGKKVIKVKIGIALKKPEAVLTKCIEAIS
                     "
     gene            complement(42942..43394)
                     /locus_tag="KOU88_000478"
     CDS             complement(42942..43394)
                     /locus_tag="KOU88_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3210397.1"
                     /translation="MVLQEKYIFIDKDLKSKEEVLNFIADSAYILGITTNKEALLKDL
                     LKRENEFPTGIKDGFAIPHTKSVNVKEASILYIKTTNELEWKTLDDSKVRYVFSLLAP
                     HKNEGNIHLKTLSKLATCLMEDDFTSEVKNASDASHLVKYITNKMKEE"
     gene            43628..45556
                     /locus_tag="KOU88_000479"
     CDS             43628..45556
                     /locus_tag="KOU88_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3210398.1"
                     /translation="MHKRLLTLFKLLNESDDKITCKTLSNHLKVSERTIRNDITSING
                     TLEKNGAIIKIKKGEGYYIDILNLALYQQYLALISDDIMDSSEIPDSPIERNQYILKY
                     ILYNNTYIKLEDLANSLYVSKFTILNDIKRIKPILSKYNLILVSKPYYGVKVEGKEID
                     IRRCISNNMINRNFENYIIGITDREIELFNNVDLIELQRVVLSEINKFNINFLDFNLK
                     NFIIHLAITVSRILDGYCLDNVLDVVLTDFQSNTTVENIFNYIESKYTIIISKADRVY
                     LYNHFITKSSLLDNVSNRVDTKIIEYVEEILEVINNQYTFDLRNDSVLFDDLVLHFKS
                     ILNSKSYNLNKVNPLINTIKSNYPLAFEITLNAIEKVFKNSIYSLTEDEIGYVSLHIG
                     AGIERFFQSNIKCKNVVLVCGSGYGSSRLLEVQLNKVFHDKINILQCLSFNQFLASEL
                     SDVDIIISTIPLNHDSIPIVLVDLKLLKKDIENISKSITNNSHIYSNLLDNFFDKNLF
                     IVNPKIKDKDELIKLMCNKLTQSEIVFPSFAESVFYRESLSSTNIDDFLAIPHPMELS
                     SIRTKICISILDEPIYWSEDSTVKLIMMLAINKDDYIKINSIYDILLKIIHDNDIRDS
                     ISNCNDFDNFLSIIKSIV"
     gene            complement(45816..46577)
                     /locus_tag="KOU88_000480"
     CDS             complement(45816..46577)
                     /locus_tag="KOU88_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3210399.1"
                     /translation="MEYTVQKLSKLAGISTRTLRYYDEIGLLKPLKINSSGYRIYGQN
                     EVNKLQQILFYRELGINLENIKNIINSPNFDSLSALKEHHNKLLAKRKQIDLLIENVT
                     KTIALKEGKYTMTDIEKFEGFKEKMIDENEKNYGTEIREKYGKDIIDTSNKKLKNMSK
                     QDYENWQNLNIEIISKLKKAFKTGDASSELAQEVAKLHHKWLSYTWNTYSKEAHSSLA
                     QMYVYDERFTSYYDREQPGLAKFLRDAIVIYTRDK"
     gene            46796..47272
                     /locus_tag="KOU88_000481"
     CDS             46796..47272
                     /locus_tag="KOU88_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBK3210400.1"
                     /translation="MNLKRSNEKREEYRRMYSDKESFLSLIQNFTSVSIAKELTLKNI
                     ELETSFICEYKGKEVDIIYKVFSKSGKVSHYIVLEFQTEMDTEIVPRLKSYREQIWKS
                     FIMKKSLEEIEDKNFKLPKVIPVVLYSGPERLSRKKGILDIVESISEFSNNSSMKN"
     gene            47370..47522
                     /locus_tag="KOU88_000482"
     CDS             47370..47522
                     /locus_tag="KOU88_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate translocator"
                     /protein_id="HBK3210401.1"
                     /translation="MRNNKSKVLLGILCLATGMAVILSMLLPGWIWSALTALILIGCG
                     ALLFFC"
     gene            complement(47682..47870)
                     /locus_tag="KOU88_000483"
     CDS             complement(47682..47870)
                     /locus_tag="KOU88_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBK3210402.1"
                     /translation="MAKVCSVCGKGKVSGNQVSHSNKHNKRTWSANLRSVRAIIDGAP
                     KRVKVCTRCLRSGKIERA"
     gene            48231..48581
                     /locus_tag="KOU88_000484"
     CDS             48231..48581
                     /locus_tag="KOU88_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK3210403.1"
                     /translation="MSAKVTNQYGNIEIDNQVIAQVVYRAAMESYGLVGLAYKSKGIV
                     ELLKGENATKGVRVEEVEEDAIAIELYVIIQYGTNISTVANNIIDRVKYVVEKMTGVR
                     VTRIDINVQGIRVK"
     gene            48600..50243
                     /locus_tag="KOU88_000485"
     CDS             48600..50243
                     /locus_tag="KOU88_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBK3210404.1"
                     /translation="MIQYIDGKRLREMFISGANNLQNNKELVDKLNVFPVPDGDTGTN
                     MSLTISYALKELAKVENDNISDIGKALSKGSLMGARGNSGVILSQIIRGIAKSIEGKS
                     KLSTEDLAKAFKNGSDTAYKAVIKPIEGTILTVVRESGEFAIKTAKKEKDVVKFLSML
                     VKESNSSLERTPDLLKNLKEAGVVDSGGKGLVLIYEGMLASIKGDNIEIKNVDLDTNI
                     STSMDFTKSTTSTDDIKYCYCTEFILESSKVEDTKIRDIMMAYGDSLAVVGDDGVIKV
                     HVHTNDPGNVLQEALKYGQLLTIKIENMKLQHENTLLDVEEKKENDSEPLEEEKEFGF
                     IATSMGEGLANIFKDFGVDHIIEGGQTMNPSTEDFMNAIKHINAKNIFIFPNNSNIIM
                     AANQAKELSDKNIIVIPTKNTPQGFAALVTFNGELSEDENKEAMMNALNSVKSGQVTF
                     AVRDTVMNEIDVKEGNIIGIAEGNLLSAGDYVDEVTSNLIEKLVDEDTAIITLFFGED
                     VTESQANELRTSLEEKFEDVDVELYYGGQPLYYYLISVE"
     gene            50324..52381
                     /gene="recG"
                     /locus_tag="KOU88_000486"
     CDS             50324..52381
                     /gene="recG"
                     /locus_tag="KOU88_000486"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBK3210405.1"
                     /translation="MDLYKDVQYVKGIGPKKADKLNKLGIFTLKDLLYYFPRQFEDRN
                     NLKKIAQLEDGEKVTIKAVISSINTFSPKEGMTLTKIDVKDETGSAKLVFFNKSYIKN
                     TFRPGDSILVFGKVKKKFNNLELTSCELEYLTNSPKNTCRFMPVYQLTYGVTNKEIMS
                     IIRTVLEDKELIIQEYMPQRIIEKYRLCSIDFAVRNIHSPSSKESLKIALYRIVFEEL
                     LILQLGLFVFKSGRNKEDGIKFETSKDLKKIISALPFKLTKAQNRALDEIIQDMNLEK
                     IMNRLVQGDVGSGKTVVALLALANCVLNGYQGALMAPTEILAGQHYISLTESLKDFGI
                     NVGLLIGSLTKKQKDTVLEQIKNNEIDILIGTHALIEDKVEFNNIGLVITDEQHRFGV
                     MQRSKLSLKGANPDILVMTATPIPRTLALILYGDLDISIIDELPPGRQPIETIAIEKS
                     KRDRAYNNLVRREVESGRQVYIVCPLVEESEAIEAKSAVELVEELRAEYFHDLRLGLL
                     HGKMKSSEKDEVMRLFKNKEIDILVSTTVIEVGVNVPNATLMIIENAERFGLAQLHQL
                     RGRVGRGSHKSYCVLIYDSKTDVCRQRMAIMEETNDGFKISEKDLEIRGPGEFFGTRQ
                     HGLPELKVANLFKHIKILKLAQQEARYILGEDNNLQLKENMALKKEIIDKFKDTLKEI
                     SLN"
     gene            52440..52994
                     /gene="rsmD"
                     /locus_tag="KOU88_000487"
     CDS             52440..52994
                     /gene="rsmD"
                     /locus_tag="KOU88_000487"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBK3210406.1"
                     /translation="MRVISGKARGLKLNTPKNEDVRPTTDRVKESLFNMINSYIMESE
                     VLDLFAGTGSLGIECLSRGAKSCTFVDISKESIDIVKSNIKKARVESESIILNLDFKT
                     AIDKLKLQNSKFDIIFMDPPYYKNMFIEAIEKIDNSNLLNEDGIIVVEHDTNDLFPDK
                     ICKLEKTRDKKYGNTTLTFYKMEA"
     gene            52996..53493
                     /gene="coaD"
                     /locus_tag="KOU88_000488"
     CDS             52996..53493
                     /gene="coaD"
                     /locus_tag="KOU88_000488"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBK3210407.1"
                     /translation="MENKPRKAIFAGSFDPITNGHLDIICRASKLFDELQIGVLNNPN
                     KKGLFSFDERVKLIEKSTSHLNNIKVVTFDGLLINYCQENGIGALVRGVRSGADVDYE
                     LQMAHMNRELNPDIETIILPSCTKYSFISSSLIKEVLLFDADIKNLVPKIVLEELKKK
                     TSGGN"
     gene            53497..54021
                     /locus_tag="KOU88_000489"
     CDS             53497..54021
                     /locus_tag="KOU88_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210408.1"
                     /translation="MKIDLEMIELFEQLEEIFRSASTIPFSHKCTVDKDEVLAIINDI
                     RTLIPEEVTQAVWINKERNKIISQAKQDATNIVEQAKKEAERIQQEYQDNIEELKKNS
                     EDVVKAYVESSEPVVQADQRAKDIVDRAERIANEIRIGSIEYAEDVLSSVEYNLREIL
                     EEVKRDKAELRPKK"
     gene            54365..56284
                     /locus_tag="KOU88_000490"
     CDS             54365..56284
                     /locus_tag="KOU88_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3210409.1"
                     /translation="MKERAKKILDFIIKNNNVTSQELQEKFNVSKRTIYYDILAINKQ
                     LGKSGNIKNVKHKFIFEGNLCDARKIISTEEDKFLDSDYRKTFILNKILLGEKISIEK
                     LTNEMLLSKNTVVQTITDVKKYLQTMGLRLEYKGKYKIIGDEYVIRELFLIIVQENVL
                     EINSISEEVSSFDTKGHIKLTDYSLLNLTKFVEFLNKRIRDGKTLYSYKYLNEAKKIS
                     YFSNCKELLCEEANENEQAYICTYISSLPSLNSEVKEDVVEEYVDKLIDKFEVNTAIK
                     LESKHEFKKNILRHLHSSYNRIRFKFPIRNPMLDETKYKHESLYKIIKSIIENEEEFP
                     VFEGIREEEIGFIAAYFGGYLRGSRDNGLRRNKVLLVCPNGLMVSKSLEIQLYKYIPT
                     IEIVGIVSIKQLKEVNVYYDYIITTIDIQNVNNVIVVNPLLTSSDVQLLMNKLISVKE
                     NEKYFNLELIIQAIRKNGVINNEEALKADLLNIIHKIDEGEMYQPMLKELINAERVNI
                     IKNVRDWKEAIKIASKPLLEDNSIEELYIENMIKSVEKYGPYIVLADRFALPHASSKE
                     GVNKLAMSLLIVEDEVDLLGKPVNIFMVLAAVDNTTHIRALASLSEMMYEEENVKLII
                     NGDKSSILELINKQN"
     gene            56297..56584
                     /locus_tag="KOU88_000491"
     CDS             56297..56584
                     /locus_tag="KOU88_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210410.1"
                     /translation="MKILAVCGFGVGSSMVLKMTIQKALKQLGIECEVENTDINSARG
                     ADCDCIFTSQELLNELKGTCNVDVYPVKKYMDLAEVTEVVQTFLSDKNDKK"
     gene            56717..57976
                     /locus_tag="KOU88_000492"
     CDS             56717..57976
                     /locus_tag="KOU88_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBK3210411.1"
                     /translation="MLDFISNNILRNPSMLIGLIAAFGLVLQKKKASDVIKGSLLAAF
                     GIIIMETGTGMLVSSIAPINGAFQSISGGAVTKGLSDVTFTASYGGIIGLAMFAGLAI
                     HLMIARFTPIKTIFLTGHMLYWFPFIFVASGVEAGLNGGVLIAFAAVLSALYWSIMPW
                     LLRKYVFDVIGDDSFTLGHPSGCLALISGFVAKLVGNKEKSTEDINIPQSLSFFREIS
                     ISGGMAVFLMFIVVGIVIPGAFKDSNEFIGTYAIKQGLSFGAGLIIMLHGVRMLINQI
                     MPAFQGISEKVVPNALPAFDCPILFNYKPNAVLIGFLVAMLTSTAMILICNYFNVFNL
                     LLIPLVITSFFECGAAAVIGESQGGIRGAIIGTAIAAIFMVVLVGISAVIYSGTIQNW
                     ILIFGGNDLSLFGIISRFIGSLFGGIL"
     gene            57979..58719
                     /locus_tag="KOU88_000493"
     CDS             57979..58719
                     /locus_tag="KOU88_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK3210412.1"
                     /translation="MKFKYIDEIRRLIDIIENEEKVNMEKAVQILVEAIESKNAIFSF
                     GASHAGILTEELFYRAGGCVLINPVFAKSLMLDTAPITHTSKMERLEGYGTALADKTP
                     IKKGDVVIVHSVSGRNPVSIEFAMKAKENKAIVICITNLSYSKSVSSRHSSGKKLYEV
                     CDLVIDNHGQKGDACVEIDGLNQKVSPTSTVIATTVMNSIIAQATQELVNKGLKNPPI
                     FYSANIDGGDELNKKIFDEYKSVIHYEY"
     gene            59042..60352
                     /locus_tag="KOU88_000494"
     CDS             59042..60352
                     /locus_tag="KOU88_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBK3210413.1"
                     /translation="MKKENKMEGIKVGMLKKLCSLAMVAIMTTTLITGCSSGNGKDSK
                     KDGEKEKLVLWMPPVENNMKEVWDPILDKFEEKNNCEVDLQIIPWDNYSEKFATAISA
                     GEGPDVGYMYAEMYPQFIESGAVEDLTNYATKEDKEQSIYIKTSEMMGGMYGMPFQAA
                     NPGVLYYNKDILEKLGEKPPKTWEDFKRICKKATQDTDGDGKIDQWGLAQGWGAKTFG
                     NLNWNWYPYLWQAGGDIFNDDLKSVKFNDKSGLEAAKFLKELQAYVPEDSLSKDSNEM
                     IESVFGPGKAAFTIMLSSAATSVFDESFPDLNWGFVTGLEDKKAATFGAVDHLSLMSS
                     AKNKELAYKLIQHMLSVESMTEFHKAIPRAPITKGEPYQGDERFKEMVENDKNVYRPL
                     VVGPHGVEIYEYLWKELQTMISGDKTPKQALDDAAKYSNDLLAQ"
     gene            60450..61367
                     /locus_tag="KOU88_000495"
     CDS             60450..61367
                     /locus_tag="KOU88_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK3210414.1"
                     /translation="MENLVREFEENSKRKKTKLNIKPYMYILPLGIILVAFYVIPIIM
                     SIYFSFTKYNIISPATFIGLENYKKLFTDETLKVSIINTIKFTVVVVPCQTILSLILA
                     VWITGKGNSKIASFAKGAIFIPVLSSMVLIGMVWRALLNGEGSIIYQVLGAFGIESSK
                     LLGDSKTALPTLMFISMWKNIGYFMVIYISAIMNLPKHCYEVAKVDGATKLQEFIKIT
                     VPLLKPTTIMVVFLGSIWSLQVFDLIYTVTGGGPGISTMSIVMHAFNLNFKNFNSGYA
                     MTVANVLFLLIAVVSILQNKLVRRDNSDF"
     gene            61383..62192
                     /locus_tag="KOU88_000496"
     CDS             61383..62192
                     /locus_tag="KOU88_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK3210415.1"
                     /translation="MKTARRLLSDGLLLFIACASLVPFIYMLIISLKITYNSYSLDIS
                     FSTVTLQNYIDIFTKKGFAQYFFNTAIVSFSGVLLNLVFSTLAGYSFAKMDFKGSDKL
                     FLFMIMTLIIPSQVTMIPLYIIMKHLGWINSYLALIMPIPTAFGVFIMRQAILGVPKE
                     LLESAKIDGCSDFRILIQIVLPLIKPALITLAIFTFMGAWNEFMWPLIATTKDAMRTL
                     TVGLSTLKTFQITNYGQMMAGATITFLPPFIFYLILQSKFVEGVSLSGIKG"
     gene            62250..63998
                     /locus_tag="KOU88_000497"
     CDS             62250..63998
                     /locus_tag="KOU88_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4091 domain-containing protein"
                     /protein_id="HBK3210416.1"
                     /translation="MEISYVLKDCTFKHNKYSVIEAETWKDKDLDIVVAKGEKFAFQI
                     MLKATEEFNCTIDKSSAISWKGLGNRVRLALNVPNSLENNFSINILGYVQDDTKAFVN
                     DAILRDKDVLVEQYLPQTFWIEGQVPEDFEENNLDIGIDIFKSFGYEDEEKVCTIDVP
                     VKVRNVVLKPLDESKFFLDLWQHPSCLARMYKVELWSDIHFEIVDNYLKELASLGEKV
                     ATVIVSDYPWAGQSCYKVYKNPSNLYEYNMVSVSKGLDGKIKCNFESMDRYIGIADKY
                     KMAKEIDLFGLLGNWCAGEFGNPVEGYKDPIRVRYFDEKDKVFKFINNTNDLKEYIGL
                     VLNHLIECGLWDRVRIIADEPNNPEVVKECIEFINSTVGTHQVKYKSATHDQNFLDRA
                     KDEIDDMSINLKLTIQNYKDIESLKKKINDKGGILTWFVCCFPEKPNSFLSSPFVENR
                     IIGWYTYYFGLDGFLRWDYNLWTEDPWKDSSYKFPIWKAGDMFFVYPGKDLKPVRSVR
                     MENLRFGIQDFELFTMLEKEKGREYIEVELMQELLNKKENAEIKGFGDIELGYSLDNW
                     GYDKVKKYVLELLDRV"
     gene            64260..65282
                     /locus_tag="KOU88_000498"
     CDS             64260..65282
                     /locus_tag="KOU88_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 5 protein"
                     /protein_id="HBK3210417.1"
                     /translation="MFGGINIKRIGIIIMFFLSISFIGFYLVIRDNSDTVKMQRGINI
                     GNALESPKDFPWDVKMSNKFFDDIKDAGFDTVRIPVRFSDYTSDSDNFKIDEEFFKKI
                     DKYVDYALDKDLIVVLDLHHFEEIMKEPRVHKEKFLKIWQQIANRYQKYDKKLVFELL
                     NEPKENLYSQLLNEYIEEAIKIIRKTNPKRTIIVGPYNFYQIDYLNELNIPKDSNIVV
                     SFHYYEPNDFAFQGNIYHKGFEHLSNITWEGTNEQMDYLKKRFDTVENWANKNKVKIF
                     LGEFGVTKEAPETSRRAWVKAVREEAEKRNFSWAYWELASGFGIYNQIEGTWDREILS
                     ALIEKR"
     gene            65287..67593
                     /locus_tag="KOU88_000499"
     CDS             65287..67593
                     /locus_tag="KOU88_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK3210418.1"
                     /translation="MKKNSKKILITLTIITNIVYILWRIFYTVPKEEGMFALICAIIL
                     LFVEIMGMMEMFVHYYGMSNIEYPEKPIISEELYPHVDVFIATYNESVDLVRKTVNGC
                     IHMQYPDKKKVHIYICDDGNREEMCILAEKMGVNYITRTEREGAKAGNLNNAMQHTNS
                     PLIATFDADMIPMHDFLIATVPYFLKNEQAKKDGEKEEYEKVGFVQTPQSFYNPDLFQ
                     FNLHSEGRIPNEQDYFYRDIQLARNRTNSVIYGGSNTVISREALEEVDGFYTYSITED
                     FATGILIQSKGYRCYAIPEVHASGLSPTDLKSLIKQRERWARGCIQTGRRLNILFRRG
                     LGFWQKISYISSITYWYASIKRFVYIMAPILFSVFNVIVVKCTLLQVLVFWLPMYILS
                     SLSLKIFSQNIRNTRWTNIYETIMFQSLMPAVILETFAISKNKFSVTNKSKLEENRMY
                     KFLQGIPYFIYMVLSIIGILKMFVAIFKMSSMTYSVVLFWLIGNLFNLVMATLFISGR
                     QQLRKSERYIAEIDFKLKQNSYVLSSKTIDISENGFAFLLENPEYISPEEEFEVEFRE
                     KSGNEMYIANMKAKIVNVVEVNSKWKYAAYITHIEDSEIDNWMCIVHDRIPTLPMTIS
                     NQLGFFDDLQINVKKRIEKTRTLSRRSPRINMNFQMDIKNTGKLRIVNFNYQYVLLNF
                     ENKSIYPKEIALEINENIVLECDLCEGKIDERGILYKVNNIDSIMQNFFLRDEMMDWI
                     LQNKTILVSKPSEKKEKSIDEFEPMEYI"
     gene            67565..68680
                     /locus_tag="KOU88_000500"
     CDS             67565..68680
                     /locus_tag="KOU88_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210419.1"
                     /translation="MSLNPWNIFRRDEMKTLKVFFCSTKYLILVFIFFINTTFISSAT
                     SDKILDLSFKKIETDLSSKITYEDTGVRIETDSSKSDKERYLYIYQNIKENWSMYNNF
                     YIEIQNKNKSSQRINLSIQSKNMLEFRLKEGSEVFLEGKNIIYSDKIKEGCIEVPGEF
                     EGKIYVNFNSLINEESNVVLDSNMLSNIVSWGITFIPSDEEHNIVIIKKISLLSEEKL
                     RFLNNIKIIGDEEVQIPVLGQSISQYEVLGLKSDSKIKYSLMGKQDNVSISQKGKLTL
                     SNKAKPGQIILQVNVDDKFKIGKKITLTESWSVNKKDKDGVPYTLVYPEQSPTVQDMK
                     KINFMNNIITFVRILFVSLVIICFGIYLYWKKCSKTK"
     gene            68698..70116
                     /locus_tag="KOU88_000501"
     CDS             68698..70116
                     /locus_tag="KOU88_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBOAT family protein"
                     /protein_id="HBK3210420.1"
                     /translation="MLFSSLIFLFYFLPITLVLYYVFRFNRTIQNMILLAVSLFFYAW
                     GEPKFVVIMIVSIIMNYIFGLLVDRYRESKIKVKVFLVLMCAYNIGVLFIFKYLAFAL
                     RNISELISTELTIPSIVLPIGISFFTFQGMSYVIDVYRRHGEVQKNPFYVGLYIAFFP
                     QLIAGPIVRYESVAEQILNRKETWNKFSIGTCRFITGLGKKVLISNNMAIVADYIYTM
                     NSQGEIAASLAWLGSIAYTLQIFFDFSAYSDMAIGLGLMFGFKFEENFNYPYISKSIS
                     EFWRRWHISLGMWFKSYIYFPLGGSRVANKDIMIRNMFIVWLFTGIWHGAEWTFVIWG
                     ILNFVFLIIERFIMFEKIENHNFIKHIYALLVVNFGWVLFRSPNLKEAYNYFKAMFGG
                     NGAIWSDYTYMFLKEYWVFFIFAFIFSVPIAKKINKFVVEQAKYSMIFNVFYPISAIL
                     LFFISVTYLVTGSYNPFIYFNF"
     gene            70131..71339
                     /locus_tag="KOU88_000502"
     CDS             70131..71339
                     /locus_tag="KOU88_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210421.1"
                     /translation="MNRFFKVRLITAIMFLIILFAFSIFNVCYSGKDTIQEIKNSIAE
                     KSSLKDTISSIDNTVNDKVIYKNTFIETYGYLQKLMGKNEFSKFSVVKDTSGKMHYTY
                     FAKAPNPVGVIADRVRKFSDEMEKQNTKLVYLMTPDKYIKGVTKFPKGIPYSYSNETA
                     DNFLNQLKKYNVDYIDFRENILKSGIPKDDLFFKTDHHWKVETSFWAFGELVEQLNKK
                     YNMNLDENHYYRDKDNYNSIVYPKSFLGSMGRKTGILYGGIDDFTLIYPKFKTNYTYY
                     TDSKSQKFELKGRFEESLILSYPFNADLNLMDGQSDKYFTYLLGNRPLVKIKNIENPD
                     GLKVLFVKDSLIVPTAAFFSSVCSSIDMIDPRYYDGDILEYAKSHDYDFVFISVYPQN
                     LTKEFFPFCE"
     gene            complement(71413..72801)
                     /locus_tag="KOU88_000503"
     CDS             complement(71413..72801)
                     /locus_tag="KOU88_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBK3210422.1"
                     /translation="MESSFLSQFLMITDFKTIFFIILLLGTFFIVRQFEKKKIKFSLR
                     TIYATVLGLILGIIIQAFAGFPNDTTQVIWLQEVSKWYSLFGSGFMDLLKMLVVPLVF
                     LSIIKVIINMKDNNLGTLTFKSLGMLLATTAIAAIVGIIVANIMKLGVGANMPTLVEN
                     QELKEINSLVDTLRGLLPSNPVMAMANGNIVATIIFATFIATSIKRLSKKHFETIKPF
                     IDFIEASYKIIVSVSMTVIKFMPYAVVALLANTITSQGISSIVSVLQFILALYISVAI
                     LFIIHLIFITLNGLNPITYIKNSTEALLLAFTSRSSLGTLPVTIESLVQNHGVDEGVS
                     SFTASLGANMGMNGCAGIYPALMAVTLANMAGVNMDMSFYVMLLIVITISSFGIAGLP
                     GTATMAVSVVISGVGLGSYFPLVGGILAIDPILDMGRTMINVNGAMVSSITVGKSLGK
                     IDKEVFSKKNIS"
     gene            73142..74476
                     /locus_tag="KOU88_000504"
     CDS             73142..74476
                     /locus_tag="KOU88_000504"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HBK3210423.1"
                     /translation="MRVIIIGGVAAGMSAAAKLKRIKPEYEVVVYEKTEIVSFGACGL
                     PYFVGGFFNDADELLARTPEKLREAGIDLNIFREVVEVDSESKKIKVKNIKTDEIYED
                     YYDKLMIATGARSIMPSIKNIKLKNVSTLKSLYDGEYLKKLLSNEDNKRVTIIGAGFI
                     GLEAVEACKKLGKDVDVIQLEDRILPQVFDKEMTDVLEEEINRHNVNLHLDEMVVELC
                     GEDKVEKVITNKGEIDTDVVIIATGVRPNTEFLSNTNIKMLKNGAIVVDEYGRTSVED
                     IYSAGDCATIKNIVSNENVYVPLATGANKLGRIVGENLAGREVSYQGSLSSSCIKIMD
                     MEAASTGITERQAKDLGINVKSKFISDYNQTHYYPGRNKIYVKLIYDADTKVILGGQV
                     AGFKDAVQRANVLAAAIFGKMTTSQLGMLDLCYAPPFARTWDVLNVAGNISK"
     gene            complement(74618..75535)
                     /locus_tag="KOU88_000505"
     CDS             complement(74618..75535)
                     /locus_tag="KOU88_000505"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011969064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBK3210424.1"
                     /translation="MIDLTLLGCGGNVPMPNRFLSSVFINYKGRKILIDCGEGTQVSM
                     KLKKCGFKDIDLICITHLHGDHIFGLLGLLSTIGNSGRTSDLTIVGPVGIVDCIRSMR
                     NLVEYVPYTLKIIENPQGNFSLDNKVLRNLEISTISLEHSIECLGYSFNFRRNPKFDI
                     DKATKNEVPKILWNKLQEGQNIVLDSKQYTPDMVLGELRKGVKISLTTDTRPIESIPD
                     FIKDSDLFICEAMYGDDLDISKAVRNKHMTFREAANLAKLGNVKQLLLTHFSPSLDIP
                     SMYLENATNVFENTILGEDRLSLRLNFDE"
     gene            75743..76627
                     /locus_tag="KOU88_000506"
     CDS             75743..76627
                     /locus_tag="KOU88_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4846 domain-containing protein"
                     /protein_id="HBK3210425.1"
                     /translation="MKVLKKITILLLITLTLVGCSNGEEKKVVEGSKKTQNSKKDEQP
                     IIVHKDANILKDRYEPPKGFKRVDVEKGSFESFLRNTKLKNYGEKVKYYDGRTKESKG
                     IYDSVFDVDIGNRDLHQCADAIMLMRAEYLYQNKLYDEISFDFVDGFKAKYSKWAQGY
                     RISVKDSGSSWYKATEYSTSYESFRKFMDIVFAYSGTLSLEKELEPVKVEDMKIGDVF
                     IVGGSPGHASIIMDMAENEKTGEKVFMIAQSYMPAQQTQLLINRKNPNLSPWYSLDFE
                     GDLTIPQWTFKRDQLKRF"
     gene            76840..78681
                     /locus_tag="KOU88_000507"
     CDS             76840..78681
                     /locus_tag="KOU88_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase C-terminal domain-containing
                     protein"
                     /protein_id="HBK3210426.1"
                     /translation="MKIRRYLILVIIILITTSQSFISYGLERFEEITIFHTNDIHGRY
                     AEGDDHIQIGNLATLKKETPNSILVDAGDCLHGLPIVNMDRGKSAIELIKCAGYDYIT
                     PGNHDFNYGKDRLFELSKSANLGENTLKFLSSNIFENGKKVFDSNDIKEIDGIKIGFF
                     GLSTQETKSKTGFKNVEGLEFKNPIESATEQVNELKGKGANVIVAICHIGTNSLSKPN
                     SIDIANEVQGIDLIIDGHSHTKFENGKQVGDTLIVSAGQYLENIGEIKLTLDTNDVEN
                     IKIENKSVRLIGKEEALKYKLDSAVSKKVDEIKEQQEKILDKVIGVTTNTLDGSYENV
                     RTKETNLGNLISDILLDKTKADISLFNGGNIRDTIEKGNITRRDIVDVFPFSNTIVTK
                     ELTGAQIKDVLEHGVKLYPEKSSAFLQVGGISYYFNPKQKEGEKITNIQKEGKPLDLN
                     KKYVVATNDYIASGGDEFPCFSKEPVLKEFGNLESAVIEYIEYKKEISKNVDGRIGIK
                     SKDELISKNHESDLILSENEKNINDNEENLSNNIKSSDSDKNKSLDKTSARESSNLGI
                     SKREAKEKSPKTGDLGFSNSIIIFIVSSTLICLLNFNQKELKDKKSK"
     gene            78986..79693
                     /locus_tag="KOU88_000508"
     CDS             78986..79693
                     /locus_tag="KOU88_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210427.1"
                     /translation="MNNILLLEDDKSLNRGISFKLKKEGYNVFSAFGIEEAKNIFAKE
                     EICLIISDIGLPDGSGFDFCEEIRKKSDVYIIMLTALDEEVDIVTGYDLGADDYITKP
                     FSLMVLISKVNALMKRVNTVKNYTLLVCDDLFFYYIENKLIIRTDDKEEEIILSKTET
                     KLLKYLMENSMQTLTKEQLLESLWDSSGNFVDDNTIAVNIRRLRQKVEKNPSEPKYIK
                     TVRGVGYMWGERSIKKC"
     gene            79687..80997
                     /locus_tag="KOU88_000509"
     CDS             79687..80997
                     /locus_tag="KOU88_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3210428.1"
                     /translation="MLKNMNLKDGLSVKDDYIMRRVIVYSVLSVLIVTLVFILFEYSR
                     LHKLYEHQIKNTQNIAGILIEKYPNDEIDIVNSIYNSDYSKVSTGEKAFKKFGYGLEN
                     KMSNDKNFSLYLKSFFKESFFIFLMMFIVVIGIIYYFIRYINKRLSKIYFIVDKMSQE
                     NYLKDTTESEETGYLVEYNEYFKEGIFSKINNCLYELNRSLKIKFIKLEKEKESVKSL
                     VTDISHQLKTPLASLKLYNTLLIEEELEEDEANEFLLTNKASINKLENLINSLVNISR
                     LEISMINIKKEDNDIKNTILNAVKSVTPKAKSKSITLNLNEFNSRIIPHDKKWTEESI
                     FNVLDNAVKYTQVNGEINISVEETANFFKIIIEDNGIGIEKNEFNNIFKRFYRGSADE
                     IESVEGSGVGLYLSRKILEEQGGNIIVSSKVGIGSKFSLFLTTM"
     gene            81114..81797
                     /locus_tag="KOU88_000510"
     CDS             81114..81797
                     /locus_tag="KOU88_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210429.1"
                     /translation="MKILYTENLSKHYGKGESLVRALDNVDLEINEGEFVAIIGKSGS
                     GKSTLLHMIGGLDIPTSGKVYIDNKNIFTLKEEELAVFRRRKIGFIFQSYNLIPSLNV
                     WENVVLPIGLDGREVDESFIKELLKSLGLENKHDVLPNTLSGGQQQRVAIARALATRP
                     AIILADEPTGNLDSKTSDEVMSILKSMSKKYSQTLVMITHDDSIAQMADRVIFIEDGR
                     VSKVGDKND"
     gene            81790..84177
                     /locus_tag="KOU88_000511"
     CDS             81790..84177
                     /locus_tag="KOU88_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBK3210430.1"
                     /translation="MINTTKIAKSNLKQNKSKSILIIITIILSTLMLSSIGIYIVDAG
                     AYQKENTIKYSGNYQGILANVDEKQADILSNHADVELTGEMNGVGVEKLEDDSNISLA
                     YMNEDALKLNSFEFIKGKLPSKENEIVLDSGALKALGYKNKDLGEKIKISYDDYKNDK
                     KIEKEFIISGILKTSEISEAGKYYYAIISESYMRNTRDMSQEDFNIYVKFNDKSNLSI
                     EQAKEKLDKIANDIGLDTINTAVNENYINALKPDMETIMGGVFVGLVIVLSSILVIYN
                     IFYISIVTKVQEFGKLRAIGATKKQIKNIVFKEGFILAGIAIPIGIILGYVLANIIIK
                     SFMDIDVKSSRLPVILSVVVISFISVVLSLLKPMKVASKVSIVDAVRYTGNKISNKSK
                     RKGYKNINLKRLSHANLERNKKRTYMTLASLILSGTIFITVSTALESFDAEKMAREHF
                     PYDIEVRLSGYEMNSDKNPKDNLNILQMDNPLSKDFFNQIKNMEGIKRIESARSVKIG
                     MEDYDVEFKYDLLQSINENDVKSLNKNIIDGKINLERLQTGDEIVITHVDTAKEMGVK
                     AGDKIRLTLYDGDKKIKKEFKVQAIAMGVPSFGIGKDFIDRTLKYDSTSSLGIYTEEG
                     KYQEIKDSIKKIAKNNGFLETDFIDSRIESNKATISFIKIMGYTLTGIIGVIGFMNLV
                     NTMITSIVTRKKELGMLQAIGLTNKQLVKMLNSEAMYYTSGMMIGSILFGGILGYIAV
                     IFLKKTGLSYATYSLPIVPILLMIVCILIAQFITTYLIGRSFNKESLIDRVRYSE"
     gene            84457..85599
                     /locus_tag="KOU88_000512"
     CDS             84457..85599
                     /locus_tag="KOU88_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBK3210431.1"
                     /translation="MNKKINYAPGPTETRENVRLARAEKTTNPDIDIDFVEFYKKTCE
                     KFGNIIGTKNDVYILSGEGILGLEAACASLTEKGDRVLVIDNGIYGEGFKDFVTMYGG
                     EYVLFSSEYTKSIDIDELKAFLDEDSNFKYATVVHCDTPTGVLNDVSKICPLLKKYGI
                     LTVVDSVAGMVGERLSVDESKIDIILGGSQKAISAPAGLTIVGISQDAKNCIKNRKTD
                     VIGFYCNLNIWEGYYEKKYFPYTMPISDIMGLDKALDNILEEGIENVLNRHEKIAYSV
                     RKSIEEYGLELFLEEGYSNTVTAIKVPESIGALELTDYMLKNYNTLVATSLNQYMDTI
                     LRIGHMGENANLNKIEHVLNVLDKSLSALGFKGNGNLLNLFNKYYF"
     gene            85618..86142
                     /locus_tag="KOU88_000513"
     CDS             85618..86142
                     /locus_tag="KOU88_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK3210432.1"
                     /translation="MEVTAKQKFTTKDMVETSLLIALVFIATKFINIRLPISINGGLV
                     HLGTAMLFISAIIFGGKKGALSGAIGMSLFDLISGWTLWAPFTFIVRGVMGYLLGKIA
                     WANGNNGNNFLINVIGICVSSIWMLFGYYVTEVILYGNFIVPLTSIPGNLMQVLIGLI
                     IALPISKVLKNCIK"
     gene            86242..87060
                     /locus_tag="KOU88_000514"
     CDS             86242..87060
                     /locus_tag="KOU88_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK3210433.1"
                     /translation="MLSVTRYSIKNVRLKPWVKFIWYFETKSNILLNNKLLPTDSIDI
                     ILNLSDVMEYKIENQDYTASNMHFNGIRDKHGFIIQHGNIRVIGISFYPFGLYPFLKI
                     PISEFNRQIVDLEVVSQLFAKKLEESLSPTQSVEKIVLYLEEVLLSILEEDLISNKYV
                     KLLNSFIYVNRYSNIKAFCDDTNINIKTLERICLKYTGYTPKILKRIYRFKMASNQLI
                     YNYKDDELFDFIYENEYYDQAHFIKEFKKFSGTSPIKFIGENKTIKENIKYSYL"
     gene            87138..87449
                     /locus_tag="KOU88_000515"
     CDS             87138..87449
                     /locus_tag="KOU88_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBK3210434.1"
                     /translation="MKIITEIVEFNVEENLSKEEFIEIVNDLELKFHSIQSGFIDTEL
                     LYDEKSQKWIMIQHWESIEDLKSASSKMFKDSSTEKFRKALKNQTVKMNIIPQIKSWK
                     L"
     gene            complement(87626..88309)
                     /locus_tag="KOU88_000516"
     CDS             complement(87626..88309)
                     /locus_tag="KOU88_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210435.1"
                     /translation="MQKEVAMNKLIKDCVNFFNDCGFSYSICGGYALELFANMHIRPH
                     SDIDIWISDTDKEKSIQYMLNQGWDIYEPLGNYLLRPIIDLNKQHIEQICVFAIKPDC
                     SFIELKKVEDDNYKMNIQCDEQLQFDFIELIHNPQKDGKFLFSQNQRIIRDMDKARLI
                     TSDNIPYMAPEVVLFCKSIYIDRLGYQKDFDVTVPLLSQEQRDWLVNALITAYPDGHA
                     WIDQLANQY"
     gene            complement(88402..89043)
                     /locus_tag="KOU88_000517"
     CDS             complement(88402..89043)
                     /locus_tag="KOU88_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3210436.1"
                     /translation="MGRKKEPDNTIQKILDISHKLFLEKGYEQTTIQDIVDNLDGLSR
                     GAIYHHFKSKDEIIKAITSRLYNDGFYGYEVKNDEGKTALEKLQYRLLHAYEQHNKQD
                     IFLMSSSLLRNPKYLATQFDEIINDIVPWIKALIEEGNQDNSMEVKNPEIAAQMFGFL
                     LNTWCIPTVYPGNPQQMIERFTLFGEQAAFMGISFMNDKIMCEYQKFVNKFSK"
     gene            complement(89217..91220)
                     /locus_tag="KOU88_000518"
     CDS             complement(89217..91220)
                     /locus_tag="KOU88_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha amylase C-terminal domain-containing
                     protein"
                     /protein_id="HBK3210437.1"
                     /translation="MKSQKRFKILDIDVYLQPFESDIKKRMKHYEDMKSKTLKNYKDF
                     SSFANAHLYYGFHQTNDGFFYREWAPNADSLSLIGDFNNWNRKSHPLRKIGSGNWEIF
                     IPGQNSLPHKSEVKVQVTANGKTFDRIPLYIKRVIQKDFGGFNGQIWQPKTPFIWTDN
                     NFDLKNITSPLIYECHIGMSTESESIGTYNEFTEKILPKIKKAGYNTIQLMAIMEHPY
                     YASFGYQVSNFYAISSRFGTPEDLKNLINTAHSMGIAVLLDLVHSHAVKNTLEGINEF
                     DGSEHQFFHSGSKGNHPAWGTKLFNYGKPEVIHFLLSNIKFWLNEYHFDGFRFDGVTS
                     MLYHNHGLGVSFDSYEKYFSMNTDIEAITYLQFANELIKEIKPNSISIAEDMSGMPGM
                     CIPIKDGGIGFDYRLAMGVPDFWIKTISNLSDEDWDLGKMWYELTTRRPGEKNIGYCE
                     SHDQALVGDKTIIFWLADKEMYWNMEINSNNHVINRAISLIKLIKLITFSLAGEGYLN
                     FMGNEFGHPEWIDFPREGNNWSYKYARRQWSLSEDNNLKYKQLLNFDKSMLELTKYSD
                     IFIQNSHELIHMDNDKKILVYSKGKYLFIFNFHPNLIQSVDISKFQNTNYKTILNTDM
                     VEFGGNTKKENLRDYDVYFNSTPPSSKMPIASRTAIVLLDNGI"
     gene            complement(91373..92011)
                     /gene="recX"
                     /locus_tag="KOU88_000519"
     CDS             complement(91373..92011)
                     /gene="recX"
                     /locus_tag="KOU88_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBK3210438.1"
                     /translation="MGIITKIEQQKRNDDRVNIYVDDKFFIAIFKELVYTFNLKKGNE
                     INEEELKPILDDEMYIKAKNKALNILSHADQSEKKLKEKLSSEFDENIIERVIDFLKS
                     YNLVNDSVLAQKIVNTNVNLNKCGKNRIKQNLYNKGINRSTINEAVSELDKDTEFENA
                     MYLAKKRYERVKKEDKKKIYQKISQHLSYKGFDYDIIKRVLNKLLNFDEYDI"
     gene            92287..92976
                     /locus_tag="KOU88_000520"
     CDS             92287..92976
                     /locus_tag="KOU88_000520"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBK3210439.1"
                     /translation="MRSENLVKMAELKNTEKLEKFNRHKGKIKIGILGGTFDPIHYAH
                     LATAEFIRDKYDIDKIIFIPSGNPPHKLCITTDKYDRYNMTLLATESNEDFLVSKVEI
                     ERKKRTYTIDTLKYLKKKYKNADIYFITGADAICSVEEWKDVKKNFELATFIAATRPG
                     ISLLRSQETIEKLTKKYNADIITVYVPSLDISSTYIREQLNEGKSIRYLVPENVENYL
                     YENKLYQYGDD"
     gene            92977..93549
                     /gene="yqeK"
                     /locus_tag="KOU88_000521"
     CDS             92977..93549
                     /gene="yqeK"
                     /locus_tag="KOU88_000521"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBK3210440.1"
                     /translation="MNLENINQRLNQMLPVGRLSHSKNVAKCAEKLCEIYGCDKEKAY
                     LAGMIHDCAKYLSDKEIEDYVNKYEIYLDPIEDGNRSLSHSVIGAYICEYEFEVEDED
                     IINAIKYHTTGREDMSLLEKIIYIADLIEEGRKFPVVDTLRELAYGGKLDEALLTSFN
                     NTLMFVINKKEEIHPRTVMARNYLIKEKLL"
     gene            93666..94016
                     /gene="rsfS"
                     /locus_tag="KOU88_000522"
     CDS             93666..94016
                     /gene="rsfS"
                     /locus_tag="KOU88_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBK3210441.1"
                     /translation="MTVEQMTKIAYDAIEDKLGQDTVIINIGKVSSLCDYFIITTASS
                     QRQVKAIADNVEDELAKLGLEPRGKEGQGTQTWVLLDYGDIMVHVFNEENRGFYNLEK
                     LWKDAPYIDIDTLA"
     gene            94370..96790
                     /locus_tag="KOU88_000523"
     CDS             94370..96790
                     /locus_tag="KOU88_000523"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBK3210442.1"
                     /translation="MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYP
                     SGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWDSFGLPAENAAIKHGIHPHKWTM
                     ENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
                     SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKT
                     MQKNWIGKSTGADLVFDIDGTDKSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTE
                     YEADVETFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKKVPLWIANYVLVEYG
                     TGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLE
                     KEGRGKRTINYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTG
                     KGESPLTTSKQFMSTTCPHCGKPARREVDTMDTFVDSSWYFLRYVDSNNENEPFSKEL
                     VNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMVLMDGSK
                     MSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLV
                     DELADVVKKDVEFGELNSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDM
                     YKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWTMIGKEGSVFDIDWPKYDEKA
                     LVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPK
                     KLVNIVVK"
     gene            97626..98294
                     /locus_tag="KOU88_000524"
     CDS             97626..98294
                     /locus_tag="KOU88_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBK3210443.1"
                     /translation="METVTNNQSGVEIQLSLFEAIKDLLLINPIFLLGIILIGIFLVV
                     IFKKNSDIPKVKTSILSLAMYYYLCLTLSHIVGIPTFGEYIRLSQLGETFFNPNINLI
                     PFSDGFSLSFILNILLFVPLGFLCPLISKTFERLRNTFLIGFGLSLFIETIQLFTLHR
                     ATDIDDLLTNVIGTIIGYFCFKLIAKLRIVKLHSDDDSMEQDYTVCIPIAIIIVALIL
                     GFFS"
     gene            98334..98414
                     /locus_tag="KOU88_000525"
                     /pseudo
     CDS             98334..98414
                     /locus_tag="KOU88_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005541856.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            complement(98777..99049)
                     /locus_tag="KOU88_000526"
     CDS             complement(98777..99049)
                     /locus_tag="KOU88_000526"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK3210444.1"
                     /translation="MSKHQFKSVSTFFTKKNVSQFYKKNNLKKIRIHDLRYTSATLLL
                     LGGTNMKVVSERLGHTDIKITMNRYSHVLKEMDKEASDNLSELLFK"
     gene            complement(99280..99701)
                     /locus_tag="KOU88_000527"
                     /pseudo
     CDS             complement(99280..99701)
                     /locus_tag="KOU88_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431042.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(99720..99818)
                     /locus_tag="KOU88_000528"
                     /pseudo
     CDS             complement(99720..99818)
                     /locus_tag="KOU88_000528"
                     /inference="COORDINATES: protein motif:HMM:NF026008.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Arm DNA-binding domain-containing protein"
     gene            100101..101471
                     /locus_tag="KOU88_000529"
     CDS             100101..101471
                     /locus_tag="KOU88_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp29"
                     /protein_id="HBK3210445.1"
                     /translation="MKLKKLLSLGLAVSMFAAGPISANALDTIYTIQGKDKYETAALI
                     ADEQNYTTAILINADSTMADGLSASGLAGATNAPIFLTKKNNIPNATLKRVEKAKKVY
                     IIGGESSIDKATETLLKDKGIEAKRLQGSDRIKTSYNVAKEINSINKVNKVILTNAFK
                     GEPDAMSAAPVAVRDKAAIVLTDGKSVPFNTTGVESYVIGGTSSMSDKLVNDTNSTRL
                     GGVDRYDTNKKIVNKFYNGAKEFYIASGTDLVYALVASPMAKNNPIVLVDIGSNKDIL
                     KNAAKVTGIGNLSDKIMLECENTINNISLPSSNKNIICGLKIDFDSKHIIWQDKGSYL
                     ECYDDNLEYYTEKYKDPTVPINIENTSTQNLDVTKLKVYGEANSTLYMGQYAKIKMDF
                     NSFGVLKPGEKCTIYLDIISLDPSRSMTLTFSYVGDKENYKYEQGLASRILFYNPDGE
                     DFFEYK"
     gene            101830..101988
                     /locus_tag="KOU88_000530"
     CDS             101830..101988
                     /locus_tag="KOU88_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210446.1"
                     /translation="MDNFLQGILASLSASLIVYIASKLFRKRKKPLKAATKSGWEFDL
                     KIRFHKTK"
     repeat_region   102274..102836
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=102274..102302
                     /rpt_unit_seq="gttttatattaactatatggaatgtaaat"
     regulatory      complement(102978..103075)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            103301..103684
                     /locus_tag="KOU88_000531"
                     /pseudo
     CDS             103301..103684
                     /locus_tag="KOU88_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431032.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            complement(103873..104868)
                     /locus_tag="KOU88_000532"
     CDS             complement(103873..104868)
                     /locus_tag="KOU88_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBK3210447.1"
                     /translation="MSIKKKVAIVFTGGTISMTVDDKVGAAIPTLSGEQILSMVTNID
                     KVADVEVFNFDEIPGPHITPYRMMELKNYVNDLLARKDITGVVITHGTDSLEETAYFL
                     DLTIDNIKPVIVTGAMRSSSELGYDGSSNLSASVCTAVSKDAMGKGVLVVLNNEVLLA
                     SEATKTNTLSLNTFKSLTSGPLGIIDCNELVLTRDIVNRTIIDTDKVESKVALFKAYV
                     GENADFIRFAVDSGYKGIVIEAMGRGNIPPQMLSGVEYAREKGLPVVIVSRCHSGRVF
                     DSYGYFGSGRDLKNLGCIFGGDLPGQKARIKLILALGKTDNLDEIKDFFEKGIYC"
     gene            complement(104989..106617)
                     /gene="aspD"
                     /locus_tag="KOU88_000533"
     CDS             complement(104989..106617)
                     /gene="aspD"
                     /locus_tag="KOU88_000533"
                     /EC_number="4.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 4-decarboxylase"
                     /protein_id="HBK3210448.1"
                     /translation="MKNHTYKEIKNIYGKISPFEFKDKLIDIAKYTAKENNRELLDAG
                     RGNPNWTCSTAREAFFTFGHFAITETRSNWDLGHLAGMPQKKGIKERFFKFINENIDM
                     PGAYLARDIINFGINELGFDGDEFVHELADGIIGDNYPLPDRMLPHMEKIVHDYLVQE
                     MKYDISGKYGDVEIFAVEGATAAMCYIFDSLMANELLKKGDTIALMTPIFTPYLEIPN
                     LPRYDFKVVNINANEVDEKGAHTWQYTKKELEKLRDKSIKALFVVNPNNPASIAMDET
                     SCNNLIDVIENYNKDLMIISDDVYGTFVEDFSSLMSKLPYNTVGVYSYSKYFGVTGWR
                     LGTFALHKKNVFDKKINDLTGELKKSVDKRYSDMSLNPSSLSFMERVVADSRLVALNH
                     TAGLSTPQQVQMAFFSAFALIDKVDAYKKLNMSICHRRQKLLFEALELPINENKNNAA
                     YYTQFDIEEWAKLNYGEGLFKFISKNASPVDVLYKLANDYSVVLLSGNGFYGPEWSIR
                     ISLANLYDEAYTKIGKAIREILNGYIVEWQKIKK"
     gene            107276..108493
                     /locus_tag="KOU88_000534"
     CDS             107276..108493
                     /locus_tag="KOU88_000534"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase"
                     /protein_id="HBK3210449.1"
                     /translation="MMNVTLTDVKEARETIKNIVKRTDLLESVKLSEKTGANVFYKCE
                     NLQKTGSFKLRGACNKIASLTDEEKANGVIASSAGNHAQGVALGAKMTGIKSTIVMPA
                     TAPLAKVSATKGYGAEVVLNGAVYDDAYAKAVEIQKETGATFLHPFNDKYVIAGQGTI
                     SLEIFEQLDNKVDTILCPVGGGGIISGVAVAAKALNPNVKIVGVQTANIPSMKESIKN
                     GKVTTAFNDTTIADGIAVKTPGDLTFEIINELVDEIVVVEETEIAESILFMMESQKIV
                     SEGAGAVCTAAILSGKYVPAKDENVVCIISGGNIDINTLYRIIGVALAKEGRRYSFST
                     IMEDKPGNFAELTRIISENGGNILSANQGKLSAGEALGKQSAEFILETIDYDHIARIK
                     KAIEEKGFKIIEL"
     gene            108588..108968
                     /locus_tag="KOU88_000535"
     CDS             108588..108968
                     /locus_tag="KOU88_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBK3210450.1"
                     /translation="MKHEVIHTNDAPAALGPYSQAIKAGNLLFVSGQVPLVPETMEVV
                     EGDVQAQTAQSLKNLKAILAESGADFSNVVKTTVFIKDMNEFGAINEVYAEYFGENKP
                     ARACVEVARLPKDVKVEIEVIAVL"
     gene            109252..109734
                     /locus_tag="KOU88_000536"
     CDS             109252..109734
                     /locus_tag="KOU88_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3210451.1"
                     /translation="MLNFFKKNKSYKLHAVVSGNSINIEKVNDSVFSKKLMGDGVAII
                     PNSDVVVAPCNGKVTVLTESKHAFGMVSDEGVEILVHIGIDTVSLQGEGFKNEVSQGD
                     TVKKGSPIISFEREKINSQGIDCTTIIIVLNHSEFSEINCMVENEVVAGQDTVIEIMK
                     "
     gene            109755..110570
                     /locus_tag="KOU88_000537"
     CDS             109755..110570
                     /locus_tag="KOU88_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK3210452.1"
                     /translation="MRVVKIFNNNALSTVTNDRKEAILLGLGIGFNKRPGDKVNEDKI
                     EKIYYVQDHMQTKFLELLKNVSPEVMDASQQIISLIPGNEGKFNNKGILSLVEHISFA
                     IDRMKNNVFLPNLMLLDIKMMYSKEFELGVKALEIIYRVCHIHLPEDEAGYIALHFVN
                     LQSNDNLAYDTLKFVKGSIDLIKECYGLELDESSLSTLRFRTHLKFLAQRIFKNEICQ
                     DDKMIEMYDYLINNHPKNKEYLEKLNVYIEKEFRYKLDKPEKIYLLLHLTKIL"
     gene            110623..112173
                     /locus_tag="KOU88_000538"
     CDS             110623..112173
                     /locus_tag="KOU88_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK3210453.1"
                     /translation="MKEKLLGGLETFAKAMVQPLMYLSSAGILMVVGVLLTNDMLLGV
                     LPFFKWEPIQIFGSLIYNCIMAIINNLAVIFAIGIPAALAKKEKHKAALIGFMSYIIY
                     LTASNTMLTSLGQLAKESKMLGLIGTGQATILGIQVVDTSVFGGIILGCIAGYVFNRT
                     SNKTFKGALQIYSGANFSFICMFFVSILIGVVSNFIWPLAQQGIASLANVIKDTGTFG
                     LFLYGFLERILVPTGLHHLIYTPFQFSDLGGVLKVGADTVSGAYAIVMTEMNLPVERF
                     SDSIYYMATGFTKMFGYIGIGAAFIYTAYKQNKKKVKATIIPLIITAVLASVTEPLDF
                     MFVFCAPLLFFVHAVIAGLFIALLKIFDVTALCGGNLLVSIIMNTTVGVEKTHWPVMM
                     ILGLAQIIVYFVVFSFLIKKFNYKTPGREDESTATGEEQSKQLNLDAGIENIIDGLGG
                     KENINTVENCITRLRVNVKDESKINEDIINLTPNSGIVRKGKDIQIIFGLHVHEVRRA
                     VEDFLEAY"
     gene            112270..113622
                     /locus_tag="KOU88_000539"
     CDS             112270..113622
                     /locus_tag="KOU88_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBK3210454.1"
                     /translation="MIITIVGGGSTFTPGIVKSIALREKELELEEIRLFDIDKKRQDK
                     VAVVVNWILKEDVKTDVKLTVTNCEKEAYTDATFIFAQMRVGKYEMREQDEKIPLKYG
                     CVGQETCGCGGMAYGLRTIQPMIKVIDDVEKYAKKDYWILNYSNPAAIVSEACRKLRP
                     NARIINICDMPIAIIDMIAGSLNINDVHNIRYDYFGLNHFGWFTSIDYKHRDLMEEIK
                     EYIKENKILLPKSYIENLNKSRSTGNRHAVSSWIHVWESVYTMLESFPKYLPNTYLTY
                     YLLSKETVEHSNINRTRANEVMESREKDLFEGVRHYLETGEISEKAFYAGLHGDWISD
                     LAVSIKNDTRSRFLVITENRGAIPNMPYDAMVEIPAYIGKDGPEVIARGPIPLFQQGL
                     MMQQLNSEKLIVEAYIENSYEKALQAFTLNKTIPSMNVAKEILDEMIEVNKEYWPELR
                     "
     gene            113753..114511
                     /locus_tag="KOU88_000540"
     CDS             113753..114511
                     /locus_tag="KOU88_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210455.1"
                     /translation="MNIINKIFWQEDRIGMITNNLEADTHSHCMLQLFLRIEDSIEIT
                     VNEKLVKCNCIIVDKNISHSFSARKKVYYSAIIEPTSIYAEQLTSKMNDFGYWICDNN
                     GLEKLRQQGTFLIDNSSKEQYLRFMEMLNNYLNIPITLKHYDDRITELLNLLRTCNCD
                     NHTISSFADKVSLSASRLSHLFKEQIGIPLKSYILFHQMECAFRELLSGKNVTEASMT
                     AGFDTPSHFAGTVKRMMGMPVSLSLKDSEFLKVY"
     gene            114558..115277
                     /locus_tag="KOU88_000541"
     CDS             114558..115277
                     /locus_tag="KOU88_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBK3210456.1"
                     /translation="MNKEYLEETKMLNYNEPQLKLLVSSKNWLELDDFHKIKSIYEFV
                     QNDILFGYNASDMLSATQVLNDGMGQCNTKATLLMALLRAVNIPCRLHAFDVTKDFQR
                     GATSKLISLLAPKYILHTWVEVFYQDRWIALEGVITDKKYLEAIQKKFFNHGGTFKKY
                     AIATNDLKNTSIDWDGKDTFIQKEAIVYDYGIFPSPDVFFSTHSQHMSKLKNFIYVHL
                     IRKIMTKNVCKARNNYIDKNE"
     gene            complement(115401..116801)
                     /locus_tag="KOU88_000542"
     CDS             complement(115401..116801)
                     /locus_tag="KOU88_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBK3210457.1"
                     /translation="METQSNNKKGNLIIAIVMTGAFISSLSQTLLSTALPNIMSDFKI
                     TADVGQWLTTIYLLIAGIIVPTTAYLINRFSTRKLFITSMSIFSIGCIIALFSNNFST
                     MLIARVLQAMGSGSLMPLLQVIILYLCPEEKRGAAMSLVGITVGFAPAIGPTLSGWLV
                     DSFGWHSLFLFLSPIAILDVILSFILLRNVGETQKLKLDIPSIVLSSLGFGGLLIGFT
                     NQGNYGWTNIATYLPILIGIMSLILFTLRQLKSKEPFLELRVFKNKPFLISTILIMIV
                     YASMMSATLMIPLYVQSVRGFSALSSGSLMLPGAILMVVLNPIAGRHLDKYGPHALSI
                     LGTGCLFLGTLSFAFLGRDTSLIHVSLMYCIRMIGISMVLMPLTTWGIKTLDRELISH
                     ATAINNTLRQISGAIGSAILITIMTSATKKAHMSSNMLSNIHGIDVAFSIAATLAFTG
                     LIVSICFIKRHQIIRS"
     gene            complement(116805..117713)
                     /locus_tag="KOU88_000543"
     CDS             complement(116805..117713)
                     /locus_tag="KOU88_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3210458.1"
                     /translation="MKGDNKVTEKQRLIITIAQKIFDQKGFQNTSISDVVKECKMSKA
                     TFYKHFETKESFICEIINYYDEKFLEIIHSINENNDIPSSEKLNRKIIAVWKNIFSRT
                     TINTYIRENFSEEQRKATSKLQTKSRANLLNEYKLSLFDNYGDKIEKIIFDLVFLLDA
                     LIHQFIYIIHVQKREINVYFIAKFTIQILDLVVENMDNLNPLIEKSMFLHKQEDEVYF
                     SLHNKSLFFKTIQDIEELIKTDTSLLENPKLLEAIKKLYVEGKNQQYDSLIMDAMIAY
                     LEKEDTLRPKVLLLNSIKNQLKKETL"
     gene            117974..118621
                     /locus_tag="KOU88_000544"
     CDS             117974..118621
                     /locus_tag="KOU88_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBK3210459.1"
                     /translation="MKKKICVAIIFALFIVFVEMFIDSSSEGSKIMTAELSKYRKGVN
                     VLSINNIIVANKKYSLPKDYSPQESSEARDAFYKMNKDAQKSGLNLKAFSTYRSYEYQ
                     DRLFKSYVKEHGEKEANRFSAKPGESEHQTGLAFDIGGDDQSCWANKKFNNTKEAKWL
                     YENAYKYGFILRYPEGKENITGYMYESWHYRYVGTEHSKNFAMNNLTLEEYLHIN"
     gene            118946..121585
                     /locus_tag="KOU88_000545"
     CDS             118946..121585
                     /locus_tag="KOU88_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK3210460.1"
                     /translation="MSYKSTYQEVIKNLDSSLSGLSKERAEELLEKNGANELKEADKV
                     PTYKLFLESFKDPLVIILLIAALVQIFLGETVESIIIFAVIIINSVLGVVQTKKAESS
                     LESLKNLSAPNAKVIRDNKKMTIPAKNLVVGDIVFLEAGDYIPADGRLIEAQSLKVVE
                     GMLTGESEPVLKHTEKISEDVSLGDQKNMVFSGAVVVYGRGSFVVTGTGMDTEMGKIA
                     GLLESAENKLTPLQQKIEDFSKKLGVGIVILALLIFIIQVARNYFMAGNGEMTQIILD
                     SFMFSVAVAVAAIPEALSSIVTIVLAVGTNSMAKKQAIIRKLPAVETLGSTSVICTDK
                     TGTLTQNKMTVVDYYMYGTNNDELDKEKVNYSYHAKLLTMVSTLCNDSHITSDGKEVG
                     DPTEVALINYSSKNDLDYDKLRSKYIRINEIPFDSDRKLMSTVNSIYGDYIMFTKGAP
                     DIVFSRCKYALKNGSKVDITDEIIEEYKHKNEEFSNRALRVLAFAIKDVPEEDFIPSI
                     DDEHDMTLVGIMAMIDPPREEVMDAVKEAKSAGIKTVMITGDHKTTAAAIAKEIGIME
                     EGDLALTGKELDALSEEQLYEKLENISVYARVSPENKIRIVKAWQHKNNITAMTGDGV
                     NDAPALKQADIGIGMGSGTDVAKDASAMVLVDDNFASIVNAVEVGRTVYSNIIKSITY
                     LFAGNLGAIVSIVFAVFAGWSNPFTALQLLFINLVNDSLPAIALGFEKSEKNIMNKPP
                     RHPDESILAGGTLKAVAIRGCIIGVVTIIAQYIGLQVSPELGVAMAFSTLILARIMQT
                     LPARSNNQTVIKLGFFSNKYVIGAVLVCLGLYSLTLIPVLRGIFSIPTTFGLYQLGIC
                     LGLALISSILMELNKLINRSEVK"
     gene            complement(121643..122746)
                     /locus_tag="KOU88_000546"
     CDS             complement(121643..122746)
                     /locus_tag="KOU88_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HBK3210461.1"
                     /translation="MKLKINKAIEMQLKKSYAIESGHSEDVFEIDCGEGINTVSYSNK
                     AVEAFNALKFDMIRGYPHSIALKDNIVDYWKDFIALDTDRICLADGSIHVIYLLNRLF
                     IEKGDKVLGYSPQFSEYETDIKMHGATYDYVLLKKEDNFKFNEKEFIEKINPEYKVIY
                     IDNPNNPTGQIIPLSSIENIVKEAAKYDIAVMVDEAYGEYMPKENSAVKLLNNYDNVI
                     ALKTFSKGFGLAGLRAGYAVLPEQLVSPIKKISTPYEVSEISRSIAANLLDDVQFIEE
                     LKEKTKDIKNQLLIPWKNLNIAETSDTVSIMTVEHKNKDIDLQQEFAKLKIRVISGSD
                     FTGLDKNFIRFRMPEEKELPEVIKAFQIIDNIE"
     gene            123107..123928
                     /locus_tag="KOU88_000547"
     CDS             123107..123928
                     /locus_tag="KOU88_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK3210462.1"
                     /translation="MGYKLIVTDMDGTLLGNNHKVTDENKTALQKVIKSGINVTLATG
                     RAFDSAKCNVDFLKEDMPIIACNGSLIREQNGNIIYSNKIDTRTCLNILDVLDKYDIY
                     YQCNSIDSMLSKKIEGREDRLSVFLGSETEVIVKDDLREEIFKKDILKFVIIEEKNPS
                     ILDEIRKELRKVQGIKITSSWPNNIEVMNEGVDKGNAVKILAEKMNIDREDIIAFGDN
                     YNDIEMIKFAGLGVAMGNAEELIKQEADYVTDTNQDSGVAKAIYKFLELKESLSS"
     misc_binding    124007..124218
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            124305..125621
                     /gene="argH"
                     /locus_tag="KOU88_000548"
     CDS             124305..125621
                     /gene="argH"
                     /locus_tag="KOU88_000548"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBK3210463.1"
                     /translation="MKLWGGRFRKAENQLMEEFNKSFGYDCVLYKKDIEGSVAHVHMQ
                     VKCGLLTEEEGKSITEGLKGILEDVENGKLVLDGEYEDIHSFTEINLIQRIGDVGKKL
                     HTARSRNDQVAVDMRLYAKEKANDLVDLISEFKATIKDVADKNPVMMPGYTHLQRAQV
                     VTFKHHLMAYYSMFDRDEKRIKNAIEILDESPLGCGALAGTTHDIDRSITCEQLGFKK
                     VVDNFMDGVSDRDYLLELMSDFSIIMMHLSRLSEELILWSSQEFGFVEIDDLYTTGSS
                     IMPQKKNPDGAELIRGKTGRVYGNLFGLFTVMKGIPLAYNKDMQEDKEGFFDSVHTLE
                     MCIQIMDRMIATLKVNEDKMKQAVKNGFLNATEVADYLVKNNVAFRDAHGIVGSIVIY
                     CEDNKKAIEDLTLEELHKFSDAFKEDIYDFIDYESILNKGIKKNLK"
     gene            125870..126208
                     /locus_tag="KOU88_000549"
     CDS             125870..126208
                     /locus_tag="KOU88_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2325 domain-containing protein"
                     /protein_id="HBK3210464.1"
                     /translation="MNLLVIGGHERMEKDYMVMAKKKGYKTKVYTTMSSKLNNSIGKP
                     DAVVILTSTVSHKMSRTVESQAKKQDILIVRHKNSSKVAFNECLDMVDECLGNCSKCK
                     LKDKQKQKNI"
     gene            complement(126335..127624)
                     /locus_tag="KOU88_000550"
     CDS             complement(126335..127624)
                     /locus_tag="KOU88_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBK3210465.1"
                     /translation="MKRNLSLLLICLLIFTSFLGSSNISFADNEPAIVAKHAVLMDYE
                     SGKILYNKDGNSKLYPASTTKVWTACLVLKEVKDLNQVIEIKDLPQIDGSSMYLKNGE
                     SFTVKQLLDALLVHSANDAAFVLARYVGGGNVQKFIDLMNSEAKKIGATNTHFNNPHG
                     LPDPNHYTTAHDMALIAREAMNNDTFRQIVKTKSLKFEATKAYPYERYFVNTNKFLTS
                     HDKITYKGQPINIKYDIVDGIKTGYTDAAGKCLLSSAVKDGRRVIVAVFNSTNADLYL
                     DSRILIDYGFDNFKCATIVDKEKYTDTKKVLFTKQHELIYEPKNSYRIFLEKDESQGN
                     YDTKTELNKIDLPIKKGAKVGTLNVYNNGKLENSIDLIAKNNLDSSLPFLTENNVLMT
                     FVKIIAGILVLLVLFIIASNIKKKKRKKARSKKNMKK"
     gene            127704..128408
                     /locus_tag="KOU88_000551"
     CDS             127704..128408
                     /locus_tag="KOU88_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBK3210466.1"
                     /translation="MKKKVKFISFFVLFILIISSIIVYKSLIFKDDIYVVSKKNLPNE
                     KTHVVENEIKGEDNNHSKVTKDIDKNFQNNKITIYISGAVNRPGIVTIESDKRLYDAV
                     ELLGGTTKEADLNGVNLSVRLEDEQHYIIPKIGEATSVTSNDDSNKLNQKNESRGEPK
                     NKSNKNISNESKVNINVATIEELDSLPGVGEATANKILQHREENGQFSSIEEIKNVNG
                     IGDKKYENIKDLICVD"
     gene            128500..129546
                     /gene="selD"
                     /locus_tag="KOU88_000552"
     CDS             128500..129546
                     /gene="selD"
                     /locus_tag="KOU88_000552"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:128548..128550,aa:Sec)
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBK3210467.1"
                     /translation="MKKEQKKLTEMTTAGGUAAKIGPEVLASVLSQLPKNDNIENLLV
                     GLDTADDAAVYKLNDDMALIQTLDFFTPMVDDPYVFGQIAASNSLSDVYAMGGKPLVA
                     MNIVCFPSCHDMDVLAEILKGGFDKVKESGALLVGGHTVDDKEPKYGLSVSGIVSPNK
                     VLSNATAKPGDKLIITKPIGVGVLNTAMKEGMVEQHIADKVIEIMIHLNKYAAMSFEK
                     FDVNSVTDITGFGLLGHTLEMAKASEVSIEIESKHVPIIEGAIEMAQMGIIPAGMYKN
                     MHYVSKDVEVVGNIEVAVQDILYDPQTSGGLLISVKEELAEELVKDMKLNGAIEAKII
                     GSVVPKGEKYITVL"
     gene            129564..130976
                     /locus_tag="KOU88_000553"
     CDS             129564..130976
                     /locus_tag="KOU88_000553"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBK3210468.1"
                     /translation="MIVLSKRELFAMLPSVDEVLSDNRIVEIINEYPRSLVLESVREV
                     IDLKRQFILRLKEDASNSVTIEFGEIIESAIERVKLNYSLSLKKVINATGTVIHTNLG
                     RSLLSEDIKDELWCAASRYSNLEYDLDNGERGSRYSHLTSTIKRLTGAEDVLVVNNNA
                     AAVLLVLSTMAKGGEAIVSRGELVEVGGSFRIPSIMALSGAELVEVGSTNKTHLKDYK
                     EAITEDTNVLMKVHTSNYRIMGFTESVSIEELVNLGKKYKLPVIEDLGSGVFIDLSKY
                     GLSYEPTVLDSIRQGADVVTFSGDKMLGGPQAGIIVGKKEYIEKMKKNQLTRALRVDK
                     LTICALEATLRMYLDETKAIENIPTLKMLTYKIEELEVKANKLFEKITALNLNANINI
                     EDGFSQVGGGSMPLETISTKVISITPEHMNVSSLEKKLRLSEAHIIARVYDNKYVLDV
                     RTIFDDEFDVIVEELRKAFN"
     gene            131090..132973
                     /gene="selB"
                     /locus_tag="KOU88_000554"
     CDS             131090..132973
                     /gene="selB"
                     /locus_tag="KOU88_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBK3210469.1"
                     /translation="MKNVVIGTAGHIDHGKTTLIKALTGRETDTLDEEKKRGISINLG
                     FTYFDLPNNRRAGIVDVPGHEKFIKNMLAGASGIDIVLLVVAADEGVMPQTVEHLDIL
                     SFLNIKNGIVVLTKSDTVDDEFRELVKEDICEKIKGTFLEDAEIIEVDSISKRGIDTL
                     IEKIDKMSDDIEDKNENSPARLNIDRVFSIKGFGTVITGTLIEGKISIEDDLVIYPQV
                     LKTKIRSIQVHGENKDTAYAGQRTAINISNVKVDDIKRGDVLAAPNSLEESMMLDVKL
                     SLVNHLDKGLKHWDRLRLYHGTREILCRAVPLDKELIESGESGYVQLRLEESIVSKKG
                     DTFVVRRYSPMETIGGGVIIDPSPKKHKKFDEKVIEALKIKEKGELKDIIEEYLKRNL
                     KNYPNIKEIMSYSGAHEEDVKRALETLISEDKVFIIGNMYMHINQYNKLKENTIKLLS
                     EYHKKYRLRKGILKEEVRSKIESNFKTREMDILLEKLSTENAIKIENNIVSLLDFEVI
                     LNDKQKEIAKKIEKRLKSCGVSSILTIDEVSEGNHNYAEVLESMIGNKVEKLDDLYIM
                     DKDIYENAKNILINYIKENKEITLGEYRDLIDSSRKNCMIILENFDRNKITKRVENKR
                     ILF"
     gene            133078..>135809
                     /locus_tag="KOU88_000555"
     CDS             133078..>135809
                     /locus_tag="KOU88_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation-associated two-component system
                     sensor histidine kinase"
                     /protein_id="HBK3210470.1"
                     /translation="MKNIIPDVKPDIKEREDMSLLFIIMGSVLLLFIIKDIEKYETLL
                     HAIYTIFLVATGVIIFNTTKFKVDSFSTFLGLIFIATGVLECIYLFNSLGIKTKSIME
                     INITISAITDLFPILGVYLSFKFVKDNKQIYSSVILFIATATLTITSLFIISGICDYL
                     GNGKSQYALGVIISIFIIIISIISGIELNSSSNKGKWEYDEKKIFNRIIVIIILSRVP
                     NLLHIVIDNRNVERILSQIIINVALYYLYNYIVSKNIKKTALELHDTNEELTKKTESL
                     KEKNKKLIYETEKIEELKGILMKRESRLQSTLDVAVNSIVVFSKDGEITYANKSFRNT
                     FGDYKEQDKLTDKIKNFNDLIESIHYVFVHEKNAEKLISTSDNKVYQAIFAPLIIASQ
                     TEGVLCVLEDKTKKKEYERKLIEANKRSKDFLESIGDGIVVLEGNNKIYVNNACREIF
                     KNNLESIDFSLVCKSEESIEKRYVIDGEVKYVEMSFSQYTNAGTNKTIIVIRDTTSRK
                     IYQIKLEESQSSYSRFIDILPDGICLLKEDLSINYANKSFLDMLAFTNIDDIKDSNIK
                     LLMNANTEEKMKFTDNMAKVLNENRSILLLEYELINSYDDIVEVELSALPFAIYNTRY
                     IMLIIKDLVHKKYSEQAEKELLERFKTDKIKTEFFANMSHELKTPLNVISSSNQLVDS
                     FYRNEKIKDYNNNIKSHVDLVRQSSYRLQRLINNIIDLTKMESGFYTLKLAKYNIVSV
                     IEDLFMNIEEYALRKDIKILFDTDLEEINVYIDKVEIERIMLNLLSNCIKFTDNGGWI
                     YVSIHYKIDKVIISVKDTGVGIPQDKLELIFEEFSQVDKTLSRNTEGSGIGLAIVKNL
                     VSLHGGDIEVVSEVNKGTEFLISLPMKGFSSEHYTEDKRIYNIQEKIKIEFSDI"
BASE COUNT        52612 a        15081 c        23208 g        44908 t
ORIGIN      
        1 tagttagaat taaggtatat ttatgcttgt ttatatagta tatcttatac ttatagttta
       61 caataataaa gtaaattaaa tcaatatatt attataaaaa atttatttat attaaataat
      121 atgttttata ttaacttaga taataaaaat tttctggaat ttttattctt atacgtgata
      181 aaaatagtta taactatgta tttcagaaaa taaaatttat aggtattttt tttagaagaa
      241 ttatttaaca ataattatag aagtaacttt caaggttgac aaattattat ggtaaatata
      301 cattataata atttattgtc aaacatatta ttttaaatat gggatttatt tactttatcg
      361 atatacggct atataataaa tatataacag agagatgata atgtgtgttt aacacaatta
      421 aatcaaatga gatatttgaa caaagaatag tataaaattt ttaaagaaat atgttgtatg
      481 agtaagaatc tacataatat tgtattatat gatattcgaa agtattattt ctaagaaaag
      541 agatttctaa agtataaaat taaatactag aattgtaaag ttaataataa ctacaagtta
      601 ttacaagctt atgctagcta gtattagttg ttaatagaag tacaactatt tcttatttaa
      661 ttaaaagatt aaatgtggaa agttttgtga taggattact tcaaatatgt aatttataac
      721 aaccataata aatttagagt gtgtaaaaat ttatttttta aagggggatt atgaaaacat
      781 caattttaat cgcattaata gaaaagacaa gccttattgt agtattgttt cttctaataa
      841 caaagttaaa aatatttaag cagatatttc aaaaggaaga atatagtttt aatgacttgg
      901 tctgtatagc attagttttt acttttttag ccatatttgg aacttatagt ggtataaatt
      961 atatggggtc aatagtaaac actagaataa tatctatagt atcaggtggc attttatttg
     1021 gtccgatggt aggtattaca gcaggagttt tttcagggat tcatagatat tttatggata
     1081 ttggggggat aacatctgtt ccatgtcttt tatcaagtat actagcaggt gtattatcag
     1141 gatttctata taagaggata ccaaaacaac atagagtaat gtatggaata ttggtaggca
     1201 tgatttctga aagttttact atattactta tatacttaat atcatatcca cattctttag
     1261 caattcaaat aatcggtgga atatatttac ctttaatagt tgggcagatt ggaataggat
     1321 ttgttatatc tatagtagag gggattgaga aagataaaaa agatatagaa gcgagaaata
     1381 aagcagaaat aaaagcactt caaagacaaa ttaatccaca ttttttgttt aattccctaa
     1441 acacaatagc ttcatttata agatttagtc cagataaggc tagagagtta ataataaatt
     1501 tatcaactta tctaagatat aatcttgaat atagtgataa cttaattgat ataaataaag
     1561 agattgaaca agttaaatct tttgtagaga tagaaaaagc taggtttgga gaattactaa
     1621 ctgtatctta tgatatagaa gatgtaaata taaagattcc aagtttgatt atacaaccat
     1681 tagtggaaaa tgcaataata catggtattt tagaaagtgg tagagctggt gtagtgaaaa
     1741 tatccataaa aaagttaccg tattcattag aaaatactgt gagaatatca atagaggata
     1801 atggtatagg tataagtgag gaaattataa ataatgtata tcaagataat atgccagaaa
     1861 ataagattgg gctttataat gtacatttaa ggcttaaact gatgtatgga agagggctta
     1921 atataagaag aatagataat gggactttga tagtatttta tgtaaaggag tagaagtatg
     1981 agagctataa tagtggaaga tgaatttcca gcaagaaagg aattgagata ttttattgaa
     2041 aataaaagtg gaatcgaggt agtaagtgaa tttaccaatg gtatagaggt gttagacttt
     2101 attcaggaaa ataaaataga tgtaattttt ttagatataa atatacctca tcttgatgga
     2161 atgctacttg caaaaacatt aaatcagttt aaatcaagac ctaaaattgt ttttataaca
     2221 gcatatgaaa gttatgcagt agatgctttt tctttggatg tatttgatta tatattgaaa
     2281 ccatattctg aagagagaat tatttctatg ctgaataaat tagaaaaaag tgagatgagt
     2341 gatattgaac tatctaatgt aaatagtaat ttatacaaat ataagaagga agcagtaaat
     2401 caggagatag aagaaataac acataaaatt agcctttgga aaggtgataa attagttgta
     2461 atagatattg atgatatata ttactgtgaa gctaatgaaa ggcagacatt tatatatact
     2521 gagaaagaaa agtttatatt aaaagaaggc atatcagaag tcgaaaatct tataaatgat
     2581 aaaacatttt ttagaacaca taggtcttat atcgtaaact taaccaaagt aaaagaaatt
     2641 ataccatggt ttaataatac atacatatta aaattaaaaa atagtgatta tgaagtaact
     2701 gtaagtagaa gcaaagtaaa agaatttagg ctgttaatgc atatataaag tcatttcatg
     2761 tacttaaata tgcacttaat gtaattaata tttatattag cataaaaaag tattactatt
     2821 tgaactggaa atagttttct taaactcata aaaatttata aagcaattat ataaaaacta
     2881 aggggatgaa tttatggtaa gctttttagg ttcaatagta gtacttatag taggttattt
     2941 tgtctatggt acttttgtag aaaaggtttt tggaaccaat gacaaaaatc aaactccagc
     3001 tatagcttgt agggatggag tagattatgt gccaatgaaa tggaagagaa tctttttaat
     3061 tcagtttcta aatatagcag ggttaggtcc gatatttgga gctatacaag gagcattatt
     3121 tggaccatca gcatttttat ggattgtgtt tggaacaatc tttgctggtg gagtacacga
     3181 ttttgcttca ggatatctat caatgaaaaa caaaggtaca tctgcatcag agttggtagg
     3241 cctttatcta ggaaatggtg caaaaatagc aatgagaata tttagtgtta ttcttttagt
     3301 attggttgga gttgtatttg taacaggtcc agcaggatta ttaaagacat tgacaggtgt
     3361 aaacgcacaa atatgggttg gagtgataat actttattat attatggcta ctgttttacc
     3421 aatagataaa ttgattggta aaatatatcc tttatttgga gcagcattat taattatggc
     3481 agtaggtgta gctggaggat taataataaa ggggtataac ataccaaata taaatttaca
     3541 aaatatgaat ccaaatggaa cacctttatt cccatactta tttataacaa tagcatgtgg
     3601 agcaatatca ggttttcatg caactcaatc accacttatg gcgagatgtg ttgagaaaga
     3661 gagtgaggca agaccagtat tttatgggtc aatggttgca gaaggtataa tagctttagt
     3721 ttgggcagca gcagccatgt catatttcca tggcatacct caacttaatg tgatatttaa
     3781 tgatggtgga gcagcaacag tagtaaatac agtatctgtt ggattaatgg gtcctattgg
     3841 aggagcttta gctatacttg gagttgtggc atgtcctata acttctggag atacagcatt
     3901 tagaagtgct aggctgacaa tagcagatgc aatgaattat aatcaagatg cagtcaaaaa
     3961 tagattttta atagctttac cattattcgc agttggtgtt gctcttacat ttatagattt
     4021 taatataatt tggagatatt tctcttgggc aaatcaaaca cttgcaatga taatgttgtg
     4081 gactggttct gcatatttag tcaaagcaaa taaaaaccat tatataacta cattaccagc
     4141 actttttatg actgtagtaa catttagtta tataatgcaa gcaaaagaag gatttagact
     4201 accagttaat atatctaatg gaataggtgt tattgtagca ataattcttg gtcttttatt
     4261 ctttaaaaaa gcaaagcata ttaagcaaca aaataatcat aaattggcaa gttagtaaaa
     4321 taataactat aaaaattaaa aaattatatt taaattatgt tcaaagaaga gactatctca
     4381 aaatagagat aagtctcttt ttcattgttg aaaggataaa aatatatttg atttcagata
     4441 aaaaagaggg ttaaatgaac taaaattttc attttgagac attctatttt tcgaatcaaa
     4501 tcttattttt attgtatgtt taatttactt ttccacatac tatttttatg atgtaaatat
     4561 taaaattaga ggtgttaaaa atggatacta aaaaatataa agataaatta ttgaaagaaa
     4621 gagaaaattt aactaattta gtagaggata tgaaagataa tactttattt ggagatacaa
     4681 ctaaacatac aagtgaaaag tattcatcag gagaattatc tagttatgat aatcatatag
     4741 gagatatggg aacagattta tatatgcaaa atatgcaaaa tagtctaata aatcatgaag
     4801 agggaagatt gtatcaaata gacttagcat tatctaaaat agagaatgga acatatggga
     4861 tttgtgattt atgtcataat caaatagatt tagaaagatt ggatatattg ccagatacaa
     4921 gtttatgtaa tgattgtgca aagaaagaaa ataatttatt aggtgatgca atgcaaaacc
     4981 ctgatgtaga agattctaac ttttattcag aagacctaac aaatttaact gatttaaata
     5041 aaaatggaat attgagagat taaaaaactg acattataaa atatattgct agaatgaatt
     5101 agaaaagagg taatgacatg aagaaaataa tatggggtat atgtatatgt ttattatcta
     5161 tagtaggtgt atatacatat aatcataata cacataatca agatagttca aaagaagcat
     5221 atagtttaaa tgacaatata aaagacgatt atgaagatgt aataataaaa aaaggaaatg
     5281 aggatgaaaa aattttagca ttgacttttg atgatggtcc agatgaggat tttacaccac
     5341 aagtacttga tatattaaag aaaaatgatg taaaagcaac tttttttgta gttggagaaa
     5401 aagtagaata taacaaagaa ttattaaaaa gacaatatga tgaggggcat gaaataggga
     5461 atcatacatt tacacatata aatgttgcaa aaaatagtta tagtagtgtt gaaaaagaaa
     5521 taacagatac gcaaaatatt ataaaaagtg taataggagt agaaccaaag atatttagac
     5581 ctccatatag agccatgagt aaaagtgtct gtgatattat agtttctaaa ggcatgaata
     5641 taattctttg gtcaaactta gaccctagag attggtctaa ccctggagta gatgcaatta
     5701 taaatactat ccttacaaag gtccaaaatg gtaatataat acttttacat gattataaca
     5761 ctaaaagaaa tgataaatca caaactatac aagctttaga agtagtaatt cctaaattaa
     5821 aagagagagg atataaattc gtaacagtat ctgaacttat acaacattta gataaaaata
     5881 agcaagtgca aaagtaaaaa tatttgtttg aagattagtg gtgattgtaa gtttaaatta
     5941 cagacatcat taatctttaa tctataaaat acacaaaaaa tattgattag tatggtattt
     6001 ttaaattttt tatacataat gatatgattt taaatatgta gaaatctaca atataaaaaa
     6061 agtagtacta ttttaaattt tgttctagtt ttattaagaa aatacaattt taataaagtt
     6121 gctctttaga gcattttttt tgtataataa taatagtgtg cttcaaataa aattggtttt
     6181 taaataattt atagggggaa aaatcattgc tatatatatt aataataatt ctactcatag
     6241 gtttagacca actgtctaaa atatgggtat tgaataattt ggtggatgta tcaacaatac
     6301 caataataaa taatgtattt catttaactt atgtcgaaaa tagaggtgca gcatttggat
     6361 tattacaaaa taatcaatgg atatttataa ttgttgcatt acttgcaaca gtatttggac
     6421 tatactatct taatacaagg aaagtacata tatttggaag gttgggaatt atattaatta
     6481 tatctggtgc attgggaaat ctaattgata gagtacgatt aggttttgta gtagattact
     6541 tcgactttag aattatatgg gaatatgtat tcaatatagc tgatgtattt gtagttgtag
     6601 gaactgtgtt tttatgtata tatgttttat tttttgaaag taaaagtagg tgatataatg
     6661 gatgaagtaa aagagttttt agtacttgaa gaggaagaag aagttagact tgatatttat
     6721 ctagcagaac aattaggtga tatgtcaaga agttatatac aaaaaattat aaaagatgga
     6781 aaagtaaagg ttaataataa agtagaaaaa gctagatatc tggttaaaga ggaagataat
     6841 attgttatag agataccaga acctaaagta ttagaagttt tacctcaaga tattccaata
     6901 gatattgtat atgaagatga tgatgtctta ataataaata aacctcagga tatggttgtc
     6961 catcctgctc ctggaaacta tgaaaatacg ttagtaaacg ggattttata tcattgtaaa
     7021 gataagttgt catcaataaa tggagttatt agacctggta tagttcatag aatagacaaa
     7081 gatacttctg gtcttcttat gatagctaag aacaattatg cacataattt tctagcagaa
     7141 cagttaaagg aacatactat aactagggag tatgaattta tatgctatgg tgtggttaaa
     7201 gaagataaaa taactgttga taaacctata gggagaaatc ctaaggatag attaaaaatg
     7261 gctgtagtaa aagatggaaa aaatgcaatc actcactttg aagttgtaga aagatttgat
     7321 aagtttacac atatgagagc taggcttgaa actggtagaa ctcatcaaat aagagttcat
     7381 gctttgttta taaatcaccc acttttaggt gattatgtat atggtccaaa agaaactaaa
     7441 tttaaattaa aaggacaaac tttgcacgct aagaagttgg gatttataca tcctactact
     7501 aaggaatata tcgaatttaa ttcagaatta cctgagtatt ttaaggaagt tattaaaaag
     7561 ataaaataac catttgtata atacttataa atcatttttt gtttttatat aagtaaataa
     7621 atttagtgaa atttaaataa aatatcttat attaaagtat tttgtttaaa aaagcttgaa
     7681 aaatttgaaa tataaatata taatttgatt tgatagatta aaaaattatc tttaaacgat
     7741 acagagatat cgtaagacaa ttgctaaatt gcactgtata ttttttatat aagagcttct
     7801 tgtcttgtga tgagaagttt ttttgttgtt taaattgaaa ttttaaataa aaataaattt
     7861 ataaaaaatt aaaagaaagg agtagatttg tcaaatagat atattatatc tttgacaata
     7921 attatgatat ggtagaaaaa gctcaattaa tggatgaaaa ggcaatagca agagcaatta
     7981 ctagaataag tcatgaaata attgaaagaa ataaaggtgt agaaaatcta gttttagttg
     8041 gaataaagac tagaggtgtg ccaattgcaa atagaatttc taagaaaata gaacaaatag
     8101 aaggaacaaa agtagataca ggagatattg atataacttt gtatagagat gatttggaaa
     8161 aaattcatgt tgaacctgta gttaaaggaa cttatttaga ttttaatgta aatgataaga
     8221 cagtagtttt agttgatgat gttttataca ctggaagaac tgtgagagct tcactagatg
     8281 ctattataga tataggaaga cctaaatcaa tacaattagc agtgctagtg gacagagggc
     8341 atagagagtt gcctataaga gcagattatg taggaaaaaa tgtacctact tctagacatg
     8401 aaattatatc tgtcagttta ttagaaattg atggagaaga ttcagttaca atcaaagaat
     8461 aattattttt aagtattata taaaagctta gcattgaata gtcagggagg aggataaagc
     8521 ttacatagat tgcacaaaat aaatattata attttatgga tgtgagtctt aatgtagttt
     8581 ttattctcct ttatttgagt ttttgatgtc gtaaaatgta aaataatgat aaattatata
     8641 ataagtatat agaggttaaa aaatagaatc tagggaatga taattaatta aaagatatta
     8701 attaaacaga gtatttattt atatataata attttggagg tttttatgaa aaaaacgata
     8761 atgtctttac aacatctatt agccatgttt ggagcgacag tattagttcc cattttgaca
     8821 ggttttaatc cgtcagttgc aattttctgt gctggtgttg gtacattgat atttcatttt
     8881 tgtacagaag gaaaagtacc tgccttttta ggttcaagtt ttgcgtttat accagttata
     8941 ctagcagcta aagaggcata tggtggagat ttagcatatg ctcaaggtgg tataatagta
     9001 gcaggattaa tttatattat aatgtcgatt atagtaaaag tagttggtgt aaataaaatt
     9061 aaattatatt ttcctgcaca agttacagga gctatgatag tagttatagg attaaattta
     9121 ttgccaacag cttttagtat ggcttcagcc aattttgtaa tagcatttat aactttagca
     9181 atagcaattt taaccaataa gtttggtaga ggatttataa aacaattagg aatattaata
     9241 gcagtttttt ctgggtatat aatctgtttg atattaagat tagtagatat aactactatt
     9301 acagaagcaa gtttatttgc aatacctaac tttacagttc ctaagttcag tttaggagca
     9361 attgtgatta tatccccagt tgtattagct gtatttatgg aacatatagg agatatgact
     9421 actaatggtg ctgtagtagg taaaaacttt atagaaaatc ccggattaaa tagaacatta
     9481 cttggggatg gatttgcgac tatagttgca gggtgtttag gaggaccagc aaatacaact
     9541 tatggagaaa atacagcagt acttgctata actaaaaact atgacccttc aatacttaga
     9601 cgtacagcaa tatttgctat attgcttgca tgtgtaggaa agtttggtgg atttcttcaa
     9661 agtataccag gttcagttat gggtggaatt agtataatgc tattttcgat gataacttat
     9721 gtaggattaa aaactataag ggacagttct tgtgtagaaa gtaaaataaa tatattaatc
     9781 atagcagtta tattattaat aggtcttgga acaacatatt tatctaataa aggtatttct
     9841 attggaatcc ctataacaag tacagtaaag ataactggtc ttagtttagc tgcaattgtt
     9901 ggaattgtat taaacagaat tttaaataat caggacttta aagttgaaga agaataaatt
     9961 taaagaataa gttgtatatt gaataactaa aattagttaa ttttctatag acatttgtaa
    10021 ttaatgttga tataatgatt aaaaataaat gaaagaaagg gcaaggtaac taggacaatg
    10081 agaatataat ctatttttta taatttaaag tattgtaatt tttgaaaagc ctattttggt
    10141 ggctttattt gcaatgctta aattaaggag agtagattat agtctatacg tttatttgtt
    10201 atgcctattt atagaatctc tccttatatt taagtgtgtt aaggagggat tttttatgtt
    10261 gttagtaaaa gtagagaatt taaagaaata ttatgcagat aaattaattt tggatataga
    10321 taaacttgaa atattagaaa atgacaaaat aggtctagtt ggttcaaatg gtcaaggaaa
    10381 aacaacatta ttaaaagcaa tattgggaga aatagaaatt gatgaaggat atacttacct
    10441 tacagaaagc tattcttata taagtcagag tgaaaataat attgaaacat gtagtcatag
    10501 taaggagaag agtcttttaa atgctccaga taaatttgaa gaacacttat caggagggga
    10561 aaaggttaag ttaaaaatag cagatgcgct gagtaataag aaaaatatca taatagctga
    10621 tgagccaact tcaaacttag ataaaaaaag cattggggtt ttggaagata tgtttaaaag
    10681 gcatgaggga gcattattat taatatctca tgatagacgt tttctggatg agttatgtac
    10741 aactatatta gaactagaag atggaaaact aaaagcttac aaaggcaatt acactgatta
    10801 tttaatgcaa aaagatgaag aagtaaaaag agctgatttt gagtatcaag aatatgttaa
    10861 agagaaaaaa aggcttgaaa aagctctttt atataaaaaa gctttaagtg atggcataag
    10921 aaaaacacca aaaagaatgg gtaattcaga agctaggttg cacaaaatgg gtggtcagac
    10981 taataagaaa aagttggact caaatgtgaa ggctataaaa agcagaattg ataaacttga
    11041 ggtaaagaat aaacctaaag tttctaaaga aatgaacatt aagatgcaag atggtatgga
    11101 gataattagc aaaaatctag tagaggtaaa agatatgact ctaaagttag aaaataagct
    11161 cctgttagat aatgtttcct ttaagataaa aagaggtaaa aagatagcat tgttaggtga
    11221 taatgggtgt ggaaaaagta ctctgataaa agaaatattg gctgataaaa atgacaatat
    11281 aaaaataaat aacaaggtaa aagtaggtta ttttgaccaa aatcaaagtt tattagatga
    11341 ggaaaagagt gttctataca atactaaagt taatagttca tttgatgaat cttttataag
    11401 gataaactta agcctatttg ggtttaaagg tgatgatgtc tacaaaaaag taaaagtact
    11461 tagtggtgga gaaaaggtaa aaatagcact atgtaaaata atattggaag ataataattt
    11521 tttagtattt gatgaaccaa caaattactt agatataaaa tctatggaag cactggaaaa
    11581 ggcactgata aatactgata aaactatgct tatagtgtct catgatagag tatttgtatc
    11641 acatatttgt aactatatta tagagataaa agatgctaaa ataagggagt ttgattgtaa
    11701 ttatgacgaa tatacaatta gcagaaataa aaaaactcct agtagagaaa accgaatcaa
    11761 aaaagaaaat cttctagtat tagaaaatag acttacaact gttatatcta tgttatctat
    11821 agaaaaagat aatctaaaaa aagaattgta tgaatcagaa tataatgaat tactaaaaca
    11881 aatcaataaa ttaaaaaata gcttttagtg ttaacttttt aattacatct atataagaag
    11941 actgaaaata tttgttggga atataagtat agttattaaa acagaaaagt attttgttag
    12001 aaaattaaaa gtaagctaat tagaaagtgg ccttattatt gtactttata agaaggccac
    12061 tatttttatt tagaatgata atgtgtagtt gtctaacatt tattttgtat ttagtgcaga
    12121 atttattcag atttaacctt aagcttggct actgtttctt cttcaggagt aacataaata
    12181 gtactgttag tttcataaat aaccatacct ggtttagaac cactaggttt tttcacattt
    12241 tttctcttag tatagtctac aggcacctga gaagaaagtt ttgacttact aaagaatgct
    12301 gctagcatag ctccttcaaa tacagtatta tcagggactt ccttaccagc acactttatt
    12361 attacatgag aaccaggaat attctttgta tgcatccata agtcatcatt atcagcaagt
    12421 cttagtgtaa gatagtcatt ttgcttattg tttttaccaa ccaatatttt aaatccatca
    12481 gaagaaacaa attcatgagg ttttgtagat gggatagtat cctttttact gtttttcttt
    12541 tgagtcttga tgtatccaac tttagcaagt tcttctttta tatcttgtaa ttcagctaaa
    12601 ttttcacagt tttcaatact taaaattatg ttttctaagt aatctatttc ttccttattt
    12661 aaggaaattt gatgagatat ctcgacttta gcatgtttca ttttgttata ctttttaaag
    12721 tatttttgag cattttcaga tggtgtcaag tttttattta attctattgt tacatcatta
    12781 caattttcat catagaagtt agcaacttca atactttcca tacctttttc taccatataa
    12841 atatatgaag taatcaattc tccttttatc ttataaatgt ctgcattttc ggattctgat
    12901 aattcttctt cttgtttttt aagtttatta taaagtctat caagcttaac agatatactc
    12961 ttctttaaat cagatgaacg ttgattaatt ctatctttaa tatccttagt tctatagaaa
    13021 tcctccagaa tacgagacat actatcctta tttatatatg ataaatcgct aaataatgta
    13081 aggtttatac aactgaaatc aactacctta tccacctttt tatctataat aatgcaagga
    13141 gagtatttgt tagaatttat atcattgaat aaattacaaa atactttgtg taaagaatca
    13201 aattgttcat cagatatatc ctttatgata gcattttgat ttacacctgc tctgtagcaa
    13261 atttctttag ctataatagg gcttatacct agaaatttag aatatataga cttaaagata
    13321 ggtccttcca attcctctag gtttttaata aacaaatcct tagatatatc atcaagaggg
    13381 ttgagtttat tttgttctgg tggtaatgaa taatcatgac caggtaaaac ttgacgaact
    13441 ctacttatgc taaaagggac tctttttata gaatctataa ttttattttc ttcaccatga
    13501 gttattatta tgttgctatg tcttcccata atttcaatca taatattttt aactgtcttt
    13561 tcttttaatt catctaaaga ttcaacactt atttttatta ttctttcaaa acctatttga
    13621 gaaatttcta ctatatttcc accttgtatg tattttctaa gtaacataca aaacataggc
    13681 gcttttagag ggttttcttt ttgataatta cttgtaagat aaactctagg atttgaggca
    13741 cttgcactta aaaccaatct aaaattttct ttattatttc ttatattaaa aattacctca
    13801 tcatcttcag gttgatgtat cttatctatt tttccacctg taagttttga tgataattca
    13861 tcgactattg aatgtataac taatccatct aatgccattt atagcacccc tttctttgac
    13921 caaaatgagt cagtaaatta attatacaca taatatacgc tttgtgacta gggggaattt
    13981 aaacaataga gattaatatt taaattgtat gattatttat atttattaga gaggaaactt
    14041 tatttttaaa attaataatt taaagtagat taaatataaa gtaaatatag tataattatt
    14101 gtgtagagta taagctatga aagtatatga actttacaga aaaaatcaat tttaaggttc
    14161 tatagtatat aaatatgaaa gaaggttgaa aaaatgagat ttatcgattt aagaagtgat
    14221 actgttacta tgcctactga cgaaatgaga gaagctatgg caaaggctcc tgttggagat
    14281 tcaatcttta gagatgaccc tactgtaaat aaacttgaag aattagcagc agctaaagtt
    14341 ggaaaagaag atgctatttt ccttccaagt ggaacttttg ggaatcaatt agctctattt
    14401 actcattgcc taagagggca agaaataatt attggtaaag gttatcacat tgtgactcat
    14461 gaggttgggg cacctgctgt aatagctgga gttcagctta gaactataga tgaagacgaa
    14521 agtggagctc taaatcctga acttgttgaa aaggcaatta gaagagatga catacatgaa
    14581 ccacagacag ggcttatatg tgtagaaaat gcatattcag gtggaacagt tgtgagtctt
    14641 gataatttaa gagaaattaa aaaaatagct gagaaacata acttaccagt acatttagat
    14701 ggagcaagat tatttaacgc agcattaaat ttgggtgtag aagctaaaga aatagcaaag
    14761 tgttgtgata gtgttatgtt ctgtgtgtca aaaggtttag ctgcaccaat gggttctata
    14821 cttgctggaa gtaaagaatt tatagcaaaa gctagaagaa agcaaaaagt tatgggtggg
    14881 ggaatgagac aagtaggtat agttgcagca gctggtataa ttgccattga aaaaatgact
    14941 ttaagattga atgaagacca tgaaaatgca aaatatttag cttgtgaatt aaataaaatt
    15001 gatggcattg aagtaaataa tgttaatcca gatataagta tggtattttt taagatgagt
    15061 gaagatatta taaaagagga tgttttaata aaagaatttt ttgaaagaaa tataaaaatt
    15121 aataaaatgg aaaatggtga atatagattt gtaactcatg tagatattac taaggaagat
    15181 ttagactatg ttttaaaaac acttaaagaa ttaataggtg tatgttaata gatatctact
    15241 agaaggatta tagctagtta ccagatgttt aattaaaaaa ttcatagaca gtttaaataa
    15301 aacatacata aaattcatat agaaatatta atatataaac atagaaagaa ctagcttaaa
    15361 aacataatat aattacccta attgtaatgg caactctccc tcacatcctc aaattatagt
    15421 tgtcattaca aaacttttcc cataaattat aagtttatgg gaattttttt atgttataat
    15481 agtttaagcg ttaatttacg aaggagcgat acttatgaaa ttttggaaac tacatggaat
    15541 aggaaatgat tttatagcaa tagatggaag attcgaccag ataaatccat ctgattatac
    15601 tgctttagca aaaaaagtat gccatagaag attttctgta ggagcggatg gattgttagt
    15661 tgtgaaagat tcaaaagttg cagatgtaga aatggtatat tataattctg atggttcaag
    15721 agcagctatg tgtggaaatg gccttagatg tttttgtaaa tttgtttatg ataattgtat
    15781 agttaaaaaa gaaagtttta cagtagatac attagatggt ataaaagata taaaagtaaa
    15841 tcttaccaat agagaaataa actctataag agtcaatatg ggaaaaggaa gttttatagc
    15901 taaggacgtt cctgtactta caaataaaga acgttttgtg caagaaagta taaaggtttt
    15961 agatagggag cttaaagtta cttctatgtt gatgggggtt cctcatacag tagttatagt
    16021 agatgaatta gatgtagatg atgtttgtaa atatggaaaa gagattgaaa ataataaaat
    16081 atttcctgaa aaaacgaatg taaattttgt aaaggtagaa gataagtata atatacatgt
    16141 ttatacttgg gaaagaggtt gtggatatac tttaggttgt ggtactggta tgactgcatc
    16201 agcaatagtg tgcaatttac ttaatatggt agaaagtagt gtaaatgtaa cgtctcaagg
    16261 tggaacagtt aaaatagatg taggagattt ctcttatatg acaggtccag cagtaaaaat
    16321 atgtgaaggt attttggagg tttaattaat ggctataagt atgactggtt ttggaagagg
    16381 agaatacaag gatgataatt attacttttt agtagagtgt aaaacgataa atcataagta
    16441 ttcagatata aacatacgtc ttccaagaaa aatttcattt ttagaggata aagttagaaa
    16501 tttagtaaaa aattatgtaa aaagaggaag agtagattta tacataaagt ttgacttatt
    16561 aggcaaagaa gatgtaaact taaattttga tgagggatta gcatctcagt atatagacat
    16621 actaaaagaa ataaaaaata aatttgatat tatagatgat attagcgtta tgaatgttgc
    16681 aaagtttcct gatattgtga aaatagaaga aaaggaagaa gatgaagatt tattgtggtc
    16741 aatgttgaat caagcagttg aagatgcatt aatcaaatta agagaaatga gaagtgaaga
    16801 aggtaaaaaa ttagctgaag atattgccat gagatgtgat ttattaaaaa atcatataga
    16861 agagattgaa aaatattcaa gtagtgttgt agaagattat agagaaaaat tgaatttgag
    16921 aataagtgaa ttactggatg acccaagtat aatagatgag aatagattag cacaagaagt
    16981 tgcaatatat gcagataaaa gcagtataac agaagaaata gttagattta aaagtcatat
    17041 agggcaactt aaaaatacta tatttaaaga cgactctata ggtagaaaaa tagatttctt
    17101 aatacaagag atgaatagag aaactaacac tataggttcg aagtcatctg atataaatat
    17161 aactaattta gtagtagaag taaaaagcga attggaaaaa ataagagaac aaatacaaaa
    17221 tatagagtaa gaatacaata ttagaagggg aatgcttaaa tgtttgtaaa aaaaggatta
    17281 ttgctagttg tatcaggacc atcaggtgca ggaaaaggta ctatttgcaa agaactactt
    17341 aaagaaaatg atacaataaa actttctgta tcagctacta caagaaaacc cagaactgga
    17401 gaagttgatg gagtaaatta tttcttcata agtaaggaaa agtttgaaga gatgatagaa
    17461 aaaggtgagt ttttggagta tgctcaaatt tatgataatt tttatggaac tccaaaagcg
    17521 gcaataatgg aatgtttaga aaaaggacaa gatgtattac tggagattga aatgcaagga
    17581 gcaaaacaaa taaaagaagt ttgcccagag ggagtattta tatttgtact accaccatca
    17641 cttaaagaat taaaaaatag aattgttgga agaggtacag aaacagaagc tgaaatagag
    17701 aagagattta gctgtgcata tgaagaaatt aaaatgatta aggattatga ttattttata
    17761 tttaatgaag atgtaaaaac atctgctaaa gaaatagaag gtataatatc atctgaaaag
    17821 aataaagtta gcagatataa aaatattata atagagaaat ttaaggagga attataatta
    17881 tgttaaaacc atctatcaat gaggtactag aaaaaataga caacagatac tatttagtag
    17941 ggactgtttc aaagagagca agaaaattaa ttgatggaga agaaccatat gtttcaaata
    18001 aaactaagga aaagcctgta tgtgtagcaa ctaaagaagt tgcaagtgga aaaataacat
    18061 atagattatt gacagaagag gaaatagaga tagaagaagc tagacatcat gctgagcaac
    18121 accaacaaat ttcagaagag gagtaaggtc atgctaaaag ataaaactgt tgtaattggc
    18181 ataagtggcg gtatagctgc atataaggct tgtgatgttg taagtaagtt aaaaaaacta
    18241 aatgcaaata tccatgttat aatgacaaaa tcagcaacag aatttgttaa accacttaca
    18301 tttcaatcgc tgagtcaaaa ttatgtagta gaagatatgt ttgaagaacc aaaaacttgg
    18361 gaagttgaac atatatcatt agcaaaaaaa gcagatttat tcttaatagt gccagcaagt
    18421 gcaaatgtta taggcaagat tgcaaatggt atagctgacg atatgttgac aactactgtt
    18481 atggcaacaa aagcacaggt tcttatagca ccagctatga atactaatat gtatgaaaat
    18541 ccaattgttc aaaaaaatat acaaacttta aagagctttg gatataaatt tattgaaccg
    18601 gaaagtggaa ggcttgcatg tggagatatt ggaacaggta aactagctaa tccagatata
    18661 atagtagagg aagttttgac taatcttact aaagagcaag atttaaaagg tcaaagtatg
    18721 atagttacag ctggtccaac tgtagagagt atagacccag taagatattt aactaatagg
    18781 tcttctggta aaatgggata ttctatagca agagaagcta tagctagagg tgctgatgta
    18841 acattaatat caggtcctac aaatctttct attccacaaa atcttaaaaa atttgttcaa
    18901 atagagtcag cacaagattt gtatgaagca gtagtatcaa atttaagtga aaataaaata
    18961 gtaattcaaa gtgcagcagt tgcagattat aaaccaaaaa cttattctga caaaaaaatt
    19021 aaaaagaaga atgatgattt atcaatagaa ctaagtagaa attatgacat tgcttatgaa
    19081 ataggaaaaa taaaagaaga taagatacta attggatttg cagctgaaac taatgacctt
    19141 atagaacatg ccaaaggaaa aataaaaaag aaaaatttag attttattgt ggcaaatgat
    19201 ttaactaaag aaggtgctgg ttttagagct gatactaata ttgtaaaaat aatagatgta
    19261 gagggaaata ttactgagta tcctaagatg aaaaaagaag aagtagccaa tgttatttta
    19321 gataaagtta aagcgttgct tgagaaataa gacctttttt aaatatgata tttgtgtatt
    19381 ttatcacagc taaagtggct gaaagctgca atttaatttt agcgagtaaa aactcgcaaa
    19441 tgtcagttaa attgtagttt tcagcattta ttttgtcata aagtataaaa tataattaat
    19501 agttaattat taaaataaag ttaatattaa taacttgaaa ttgtttataa attctgaaat
    19561 tttaatatct tgtaaagtat attaaaatat gaacaatata ttaaatttaa gtagaggttt
    19621 tataatgaaa aaatatgcaa aggtaatagt tagaagtaat actatatata cagataattt
    19681 atttacatat caaattcctg tatttttatc tgatgtaata aaaatcgggc acagaatatt
    19741 agtacgattt ggaaaaggta ataaaccaac agaagccttt gtatttcaat ttacagatag
    19801 cttagatgaa aaaataaaaa taaaagaaat tattgatata ttagatgaaa atccaatatt
    19861 tagaaaagaa gatttagagt tggtttattg gatgaaaaat agatatttgt gtacttatat
    19921 agaatgtata aatttgatat atccaaaggg atacaaatta aataattata aagtagtcct
    19981 attaggtgaa agtttaagtg gattaaatga tattgaattg aaggaaaaaa tatcaacttt
    20041 aagtgataaa aatagagaaa tagtagagaa agtgattgat agtaaaggta aaattaaggt
    20101 tgataagtta aaatatatac caaacttaaa tagttctttg tacacaatga ataaaaatgg
    20161 aattataaaa ttatgttggg aatataaaaa tcacaaaaat gaaaagaaag tatgttatat
    20221 atctttgagt ttagaaagtg ataagattga cgattatata gagcaaaata aaataaatgt
    20281 gggaagtaaa caaaaagaga tattaagttt tcttaaaaat aatgaaaatg tagagataaa
    20341 tgatttattg gatttattaa atgcttcaaa acaaagtata aattctctaa gtaagaaaaa
    20401 gctaataacc ctagaattta aggattatta tagagagcca aaaagtattt acaaatccgt
    20461 actaaaaagt ataaaattaa acaatgagca acaagaagca gttgatgaga taaagtcgaa
    20521 tatgtttgta gatgataaaa aaccatactt aattcatgga gtaactggaa gtggaaaaac
    20581 tgaagtttac atggaaataa tagaatttgc tctaaatcaa ggcttagaca gtatattctt
    20641 agtacctgag atagcattaa ctcctcaaac aatagatagg ctaaagagta ggtttggaga
    20701 tttagttgga gtgttccaca gtaaactatc tgaaggagaa aaacatgatg tttacaaagc
    20761 tgtcaaagca ggtaaagtaa gagtgttaat tggagctagg tcagctttat ttgcaccttt
    20821 taattcctta ggcttaataa taattgatga atgtcatgag tcatcatata agtctgagaa
    20881 gaatccaaaa tttaatgcta tagaagttgc tagatttatg gcattaaaaa ataatataac
    20941 tcttatttta ggttcagcaa cgccctcaat tgaagagtat tatagggcaa aatctggaga
    21001 atacaaactt ataaatataa aaagtagagc aaatgataag cctcttccaa acattgaagt
    21061 ggtagacatg aaagatgagt tagataaagg aaatagaagt atatttagtt tgaaattaca
    21121 aaaagaaata cgttatgcga ttgaagaaaa taatcaagta atactatttt taaacagaag
    21181 aggttatgca aattttgtat cttgtagaaa gtgtggatat gtgtttcaat gtgaaaattg
    21241 tgatatatct ttaacttatc ataagaaaag taatactgga agatgccact attgtggata
    21301 tgagaaagaa attccaaaag agtgtcctga atgtaaaagt acttatgtta agccatttgg
    21361 agttggaact caaaaaattg aagaggaatt aaaatatatt tttccagata taaaaacttt
    21421 gagaatggat aaagatacaa cttcaaaaaa aggtgcttta gatgagatat taaataaatt
    21481 taaagataaa gaagcagatg tacttattgg aacacagatg ttaagtaaag ggctggattt
    21541 tgagaatgta actttagtag gtattttgtc tgcagacatg atattaaatt ttccagactt
    21601 taaaagtttt gaaactacat ttcaattgat aactcaagtc tctggaagag cagggagagc
    21661 tgataaagag ggaaaagtag tacttcagac ttatgacact gaacactatg ctattaagca
    21721 tgctattgaa tatgattatg agggttttta tgaagatgag ataaaaataa gaaaagcatt
    21781 tggatattct ccttttaata atatgttaag tgtagttgtt agtggtgaag atgaaagatt
    21841 agtgataaaa aatataaaaa atatgcatgc atcattgatt tatttattag aaaaaagggg
    21901 tataaatgat ttaggattta tattaggtcc aaatccatgt tcaatatcaa aaataaatca
    21961 aaattataga tggcaaatac tctttaaaga tgaaaatatt gaaattaatc tcttaaaggg
    22021 tataataaaa tatatatgta taacaaaacg agatttgata tttgataaga atatcaatgt
    22081 atctatagat attaatccaa acagtgtatt ataaatttag gaggaattat aatggcttta
    22141 agacaaatag ttcaaatagg agaaccagta ttaagaaaaa aatcaaaaaa ggttgaaaaa
    22201 attgatgaaa agataataca attattagat gatatggcag aaactatgta tgatgcagat
    22261 ggtgttggac tggctgcacc tcaagttgga atattaaaaa gagtagtagt aatagatatt
    22321 ggagaagatc ttatagaact tataaatcct gaaataatag aaacatctgg ggagcaaata
    22381 gatgaggaag gatgtttaag tgttgttgga gaagcgggaa atgttagaag accaaattat
    22441 gtaaaggtca gagctttaaa tagaaatggt gaaacaatag agttagaggg agaagagctt
    22501 ttagctagag cattttgtca tgagatagac cacttagatg gaattttatt tgttgacaaa
    22561 atagaaaagt agtaggagtt gatttgatga aaatagtatt tatgggaact cctgatatag
    22621 cagttccatg tttacaaaaa ataatagatg agaagtatga aatattgggt gttgtaactc
    22681 aaccagataa accaaaagga agaggtaaaa aactaggtat gagcccagta aaagaactgg
    22741 caattgaaaa taatatacct gtatatcaac cagtaaaggc tagagataaa gaatttatag
    22801 ataaaattaa atctttaaat ccagatgtaa tagtagttgt agcttttgga cagatacttc
    22861 caaaagaaat attagagatt cctaaacttg gatgtataaa tgttcatgtt tctttacttc
    22921 caaaatatag aggtgcggca cctataaatt gggtaataat aaatggtgaa gaaaagactg
    22981 gtgttacaac tatgtatatg gatgaaggat tagatactgg agatatgata ctaaagacag
    23041 aagtaaatct tgatgaaaat ataacagcag gagaacttca tgataaaatg atgaatatag
    23101 gagcagaaac tttaaaagaa acattaagat taattgaaga aggaaatgct ccaagagaag
    23161 tacaaaatca tgaagaattt tcctatgcgc caataatgaa taaatcatta ggtaacatag
    23221 atttttcaaa aagtgccaga gaaatacaca atttagttag aggagtaaat ccatggccaa
    23281 gtgcttatac tacctataat gatgtcataa tgaaagtttg gaaaactaaa gtgttagatg
    23341 aaaaaagcac aaaagatgta ggtacaataa ttgatgtaag caaagatggg ataaaagtaa
    23401 gtactataga taatgtactt ttaattgaag aaattcagat gccgaataaa aagagaatgt
    23461 tggttggtga atatataaaa gggaatacta tagaaactgg tttagtattg ggttaggtga
    23521 aaagtatgac agatataaag aagtatttaa caagtgttgg gattttgatt ttaatattag
    23581 gaattttgat aggagttgtt aattttttta taataagttt aactcaaata ttctccttga
    23641 tgataaatat tataataata tcactaatac ttataatact atgttcaaca gcagttactt
    23701 atagagtaat taaaggaaag tatgttaact caaatataat gaaaataaat tttaatattg
    23761 tcagtggatt atttcctatt atatctttca ttgcatcatc atttggtatg tcaaaaagtg
    23821 atattagaag aatatatata aagttaaata atgaatatat atacagtaat aaatataatt
    23881 ttaatccaga ggatataata attttaatac ctcattgtat tcaagagaat agttgtaaat
    23941 taaaagttac taatgatata gataattgta aagaatgtgg aagatgcaac ataggagaat
    24001 taattaagct aaaggaaaaa actaatgtaa aaatatttgt agctacagga ggaaccctag
    24061 ctagaaaaat tataatggac actaaaccta aagctgttgt agctgttgca tgtgaaagag
    24121 atttgacatc tggaatacaa gatattaaaa aaattcctgt tttaggtgta tttaacaaaa
    24181 gacctaatgg accttgtgta aatactaatg tagacatgat ggatattgaa aaagctatag
    24241 gctttttaac aggaaaaaat atattagttt gtaattaaac tgtttttaag ttaagtgaat
    24301 attaagagga tgtataataa aaatatattt taggagagtg ttatttatgt accctgtata
    24361 tggcggtttt tggggatttg acccaacaat ggttgtatta attccagcta tattacttac
    24421 tatatatgca caatttaaag tgagttcaac aacaaataag tatttaagag taaatacacg
    24481 tcgaggatat actggagagc aaacagcaag aagagtactt gattcaaatg gtttgtatga
    24541 tgtaaagata gaaatggtta gagggcatct aagtgaccat tatgacccaa gaagaaaggc
    24601 tgtaaggttg tcagaagatg tatattatgg aacatctata acttctgttg cagtagctgc
    24661 acatgagtgt ggtcatgcca tacaacatgc taaaggttat gcacctcttc aaataagaag
    24721 tagtttagta ccagtagtga attttgcttc aagtatatct tggtttttaa tatttttagg
    24781 atttattatg gctggtccat ttttaaaaat tggtatacta ttgttttcgg cttcagtgtt
    24841 attccaaata ataacattgc ctgtagaatt taatgcttca agtagagcaa tcgttcaact
    24901 tgggaattta ggtattatag atgaaagtga gtcaagacaa agtagaagag tactttcagc
    24961 agcagcttta acatatgttg cagcagcatt ggtttcaata cttcaattac ttagattgtt
    25021 actaatagct caaagaagaa atgactaaaa gtaaagtggg ttgtttagaa acaacccttt
    25081 tttatgttta ataaaaggga gaaatttata tggatgcaag agaagttgga tttaaagtat
    25141 tatgtgatat agaaaaaaat gacaattatt caaatattgc aataaataag cattttaaaa
    25201 atttagaaat aagtgatatg gatagaggac ttgcaacaga gttaatttat ggagtaatag
    25261 aaaataaata ttatttagat tatataatca ataaactttc aaaaataaag gtaaaaaaaa
    25321 tgtcaactta tgttaaaatc tttttaagaa tgggaacata tcagatttta tttttagata
    25381 gtatatcaga ttatgcagca gttaatgaaa ctgtaaaatt atctaagaaa tatgataaaa
    25441 aatcttctgg tttcataaat gctattctta gaaatgaaat aagagctaaa gagactataa
    25501 tggacataac tgaggaagat agtgtaaaat acttatctat aaagtattcc tataactctt
    25561 ggattataaa aaactggata gataaatttg gacaagaatt tgctgaagat ttgttggaag
    25621 caaataatga aaagcctagt atctatataa gaacgaatac acttaaaata agtagagaag
    25681 agcttattga aaaattaagt gaaatgggta ttgtatgttt aaaagttcct atggtagaag
    25741 aagctattaa agtcgaaaaa atgaaaaata tagaaaaaaa tgaattattt aaggctggtt
    25801 tatttacaat tcaagatata agttctatga tagtagggaa agtaattaat ccaaaagaag
    25861 gttcatttat tttggatgta tgtagtgctc ctggagggaa atctactcac ttagctactt
    25921 taatgaacaa tactggtcaa gtagtagcta gagatatttt tgagcataaa ctaaagctta
    25981 taaactctac tgtaaataga ttggggctta aaaatgtgtt tgtagaaaga tttgatgctt
    26041 ctgagattga tgaaaatagt ataagtaaat ttgattatgt tttagcagat gttccttgct
    26101 ctggttttgg tataataaga cgtaaaccag aaattaagta taagaaagaa gaagagttaa
    26161 aggacatcac ttctatacaa aagaaaattt tagaaaatgc atctaaatat gtcaaagttg
    26221 gtggaacttt agtatatagt acatgtacaa ttcaaggtgt ggagaatata aatatagtta
    26281 cttcttttgt tgaagaaaat cacaactttg aatttgttcc aattgataca gtaaatgtag
    26341 acttagacaa tcaagataaa ggatatttaa agatatatcc taatattcat ggtatagatg
    26401 gttttttcat agcaaaatta aagagaataa ggtagtgaga gaatggaaaa gaaaaagata
    26461 gtattaaaaa attttactga agatgaactt aaagaattta tgaaaactat agatgaaaag
    26521 ccctttagag gaagtcaaat attctcttgg atatataagg gtgcaaaaac ttttgatgat
    26581 atgaacaata taccaaaaag tttgagaaat aaattagaag aggtttcatg tatagggcat
    26641 atagatatag aattaaagtt agaatctaag gtagataata caaaaaaata tttgttttta
    26701 ttagatgatg gaaatataat agaaactgtg atgatggatt atgatagtag agttactgtc
    26761 tgtgtttcta accaagtagg ttgtaggatg ggatgtaatt tttgtgcatc tacaatggat
    26821 ggattaatta gaaacttaga gccatgggaa attttagacc aagttattaa aattcaagaa
    26881 gatactggta agagggtatc aaatcttgta ttgatgggga gtggtgagcc acttgataac
    26941 tttgaaaata caaaacaatt tttaaaaata attaacgaaa aaaatggtct taatataggg
    27001 tatagacata taactctttc aacttgtgga atagtaccta aaatgtatga gttggcagac
    27061 ttagaaatag ctataaattt agctttatca cttcattcac catatgatga agaacgaaga
    27121 aaaattatgc ctgtagcaaa tgcttattct attgaagaaa tattgaatgc atgtagatat
    27181 tatataaaaa agacaaatag aagggttaca tttgaatatt ctcttataaa aggggtaaat
    27241 gactcagaaa aagaagcaaa ggcattagct aagctcctaa aaggtatgct atgtcatgta
    27301 aatttaattc caataaataa agttgaagaa agagaatatg aaaagccaga taaagcattt
    27361 atttataaat ttagggatag tttggagaag aacaatatac ctgccacagt taggatgtct
    27421 atgggttctg atattagtgg agcttgtggg caattgagaa gaaaatacaa gtaatttgta
    27481 aggaggaagt cgtatggttt atagttgtgc ctcccatata ggaaaaataa gaaaaaacaa
    27541 tgaagactat tgtgagggag aagttataga tacagaacat ggtccaatag gaatatttgc
    27601 catagctgat ggaatgggtg gacataaaaa aggtgaagtc gccagtaaat tagcagtaga
    27661 aaatataatt gattttctaa aggaaaactt attacaacat gataatgtaa aaatagacta
    27721 tatagatgat atattaaaac aggcttataa taatgtaaac tcaattgtgc acaaaaaatc
    27781 tatggaagat atagaatttg aaggaatggg aactacatta gttacggcta tagtgtataa
    27841 taatgtctta tatgtggcaa atgttggaga tagcagatgt tatttgttaa cagatgaaaa
    27901 atttgataaa ataactatag accattccgt ggttgaagaa cttatgatgg cccatgtcat
    27961 tacagaagaa gaggcaagaa gacatccaca gaggaataga ataactagag caattggaac
    28021 agatgatatg gttgttgtag atatttttaa gaaagaaatc aaaaaaagtg atataatact
    28081 tcttgcgaca gatggattaa ctgggtttat tgatgatgaa gatataagag atttaatatt
    28141 agattatgaa tatgagagaa ctagtaatat aagtgaagaa ttgataagta tggccaatga
    28201 tgtttctggt aaagataatg tttcggttat agtgataaaa gtataattag gacggtgata
    28261 ttgtgggaga tacaatttta ggaaatcgat atgaaatcat caggaagatt ggtgatggag
    28321 gaatggcctt tgtatatgag gctaaagaca gattattaaa caggactgtt gcacttaaag
    28381 tacttagacc tgaatttgta gatgatgatg aatttctaac aaagtttaaa agagaggcag
    28441 aagcagtagc aagtctttca catccaaata tagtaaatgt ttatgatgtt ggtgaagatg
    28501 gaaaagttca ctacattgta atggagtttg tagatgggaa gaatctaaaa gagattatac
    28561 aagatgaagg tatattagat gaatatactg cattagatat aacaaaacaa atagctatgg
    28621 cacttagtgc agcgcacaaa aaggggatta tacatagaga tataaaacct cataatattc
    28681 tcatatcaaa tgaaggaaga gtagtaaaag tggctgattt tggtatagcc aaagctgttt
    28741 caaattcaac aatgactaat attggtagta taataggttc agtgcattat ttttcaccag
    28801 agcaagctaa aggtaaattt gtaactaata atgctgacct gtattctcta ggtatagttt
    28861 tatatgaaat gttgatagga aaagttccat ttaggggaga tagtccaatt tctatagcac
    28921 ttcaacacat taatgatgat atagacttta catcagaaga aaaagttagg attcctcaaa
    28981 gtgtaagaac tacaataaaa aagcttacag aaaaatctag tgcagataga tatcaaactg
    29041 ctgaagaatt gatagaagat atagagtata tagaaaaaaa tattgattta gattttataa
    29101 aagaatatga tgattttgca actaagaaaa ttgatgaaaa ggaaattaat aaagttgtaa
    29161 atccaacact tgcaaaacca gctcctgaaa aagtggttaa gcctgttgaa gtagctgatt
    29221 tggatgatga tgaagattac tatgatgatt tttatgaaga agatgatgat gaagatgaag
    29281 aagaggaaga gataatgaga gctaaaaaga atcagagacc taagagtact ccaagtaaga
    29341 gaactaagaa aaagaagaaa aaacaggaaa gcccaaaatc tagaagaaga ttaaaagtaa
    29401 ttgcggctgt tttgatactg atattgtgtg ctcaagtatt cttagcatat aagtttttat
    29461 ttgctggagg gtttggcaat aaatctttga ctgttcctaa tcttgtaaat atgacattag
    29521 aagaagctca aagtgctgtt gaaaaagaag gattatacct gagtgtaaaa agtgaagagt
    29581 ataatagtga agttgatgaa aattgtataa tatcacagac acctgaaggt ggaagtacaa
    29641 atgtcaaaaa gggtgatact ataaatgttg tcgtaagtaa aggttcaagt caggcatctg
    29701 ttcctaatgt agtgggactt actttgagta atgcaaaaca acttattgaa gaaaataact
    29761 taaaagtggg aactgttaag tatgaataca gctcaatata taaagaaggt acagttttaa
    29821 gtcagagtcc aggtgctggc tcatcaagag ctcaggaagg tgatgaggta aacctatatg
    29881 taagcaaagg ttcagaaaaa tcaaatacac agactccaac agtaccagat aaaaaaccaa
    29941 caacaccaga gaataataca ccaacagaac ctggttcaaa ctcaggaaac agtggtggaa
    30001 attcaggagg ctcaaattca ggaaatagtg gtggaaactc aggcaataat ggaagtaact
    30061 caggaggttc aaactcagga aatagtggtg gaaactcagg aggttcaaac tcaggagata
    30121 atggaggaag ttcaggaggc tcaaactcag gagacaatgg aggaagttca ggaggttcaa
    30181 actcaggaga caatggagat agttcaggag gctcaaactc aggagataat ggaggaactt
    30241 catcaggaac tggcgcaaac attggtaaaa cagaataaat attaataaaa taagagctgt
    30301 ccttttatag aaaatatttt ctttaaaggg cagtttgttt tgtataaaat actgaattgg
    30361 ttataatata aggagaaaag tatttatgaa gaagaaaaca gttttaatta caggaggagc
    30421 tagagggatt ggtaaagcta tgtctaaagc ttttgcaaaa gaaggttaca atgtattagt
    30481 aaattttaat aagtcagaaa atgaagctaa agagttgtac actatattaa atgaaaaaaa
    30541 tttttctgta aaacttttta aggctaatat ttcaaataga gaagatgtag aggatatggt
    30601 agattattgt ataaaagaat ttggaggatt ggatgtactt gtaaacaatg ctggtgtaag
    30661 tcaagataag ttgtttacag atataactga tgaagattgg gataatatga tgaatattaa
    30721 tttaaaagga agcttttatt gttcacaagt tgctttaaaa tacatgatat cagaaaaaaa
    30781 aggaaatata attaatatat cttcaatctg gggtatatca ggtgcctctt gtgaagtgca
    30841 ttattctata acaaaagcag gcataatagg tatgacaaag gcattagcta aagaagtagg
    30901 accatcaaat attagagtaa atagcatagc tccaggtgtc attaatactg acatgttatc
    30961 tggatataat gaggaagata tagacgctct tgtggaagaa acccctctaa tgaggctagg
    31021 aactccagaa gatatagcaa attgtgctat tttcttggca tcagacaaat caaattttat
    31081 cactggtcag gtaattagtc caaacggagg atttgttatt taaaaaaaat gtggtattat
    31141 ataaaaatag gaaagaataa cacgatatac tactcataaa cagtatgtgt ttatataaat
    31201 tttataaagg gaggcatttg atgctagaag gaaaaattat aaaggggatt agtggatttt
    31261 attatgtaga tacttataat ggtatttatg aatgtaaggc tagagggata tttagaaagc
    31321 agaaaataac acctttggtt ggtgatagag tcaaaataag cattgttgat gaagatgaaa
    31381 aaaagggtat cttagaagaa atcgacagta gagatacaga acttataaga cctcctattg
    31441 caaatgtaga taaagcatta atagtattcg caataaaaaa tcctaaacca aacttatctc
    31501 ttttagatag atttatagtt ttggcagaaa aagaaaattt agaaactgta ataatcctta
    31561 caaaagcaga tttagatgat aatgatacat tagaaactgt taaaaatata tatgaactta
    31621 gtggctataa agtcattcct gtaagtaata ttactaagtt aaatatagat aaagtaaaag
    31681 aagaattaaa agaaaatgta gtagtgtttg caggaccatc tggagttgga aaatcaagct
    31741 tattaaatga aatagatgaa aattttaaac ttcaaacagg agttgtaagt gataaaataa
    31801 aaaggggaaa acatactact cgtcacgctg aacttttaaa attagaattt ggtggaatgg
    31861 ttgcagatac accaggtttt agttcccttg tccttgaaga tatagaggaa gttgaactta
    31921 aagattattt tatagaattt gataaattta atgattgtaa gtttggttca aagtgtattc
    31981 atgaaaatga acctaattgt gctataaaag aagctgttac aaatggagaa atatctaaag
    32041 aaagatatga tagttatata cagctgctac atgaaataag acaaaataat agtaggaggt
    32101 attagaaaca tgattaaatt agcaccatca atattatcag cagattttgc aaaattatta
    32161 gaagatgtaa gaaaagtaga aagtgcagga tgtgaatatc ttcatatcga tgtaatggat
    32221 ggacactttg taccaaacat tacattagga ccacttgtag tcaaaagttt aaagaaagaa
    32281 aatataaata tggtatttga tgctcatctt atgatagaaa atccagacca gtatattgaa
    32341 gaatttgtaa aagcaggatg tgatataata actgttcacc aggaggcttg tgttcatcta
    32401 catagaacta tacaaaatat aaaatcacat ggaataaaag ctggtgtagt acttaatcca
    32461 gctacaccag tagatacgat taaacatgta ctacctgatt tagatatggt attattaatg
    32521 tctgttaacc ctggatttgg aggacaatca tttattcctt gtgttttaga taagattaaa
    32581 gagttaaaag ctattataga tagtcaagga ttaaacattg atatagaagt tgatggtggt
    32641 ataagcccta aaaacgtagc cgaagttgta caagcaggag ctaatataat agtagcaggt
    32701 tctgcaatat ttggaagtga tgacattcaa gaaacagtta atttatttag aaagaatgct
    32761 tctcttgaag aattagttta aatttaataa tgaaaatctg tattgtttta aatggcgaaa
    32821 ttgaagatta cgaagttaca agagatatta taattaagga atgttatgac tgcataatat
    32881 gtgcagatgg aggggcaaat cacacttata aaatggaaat aatgccagat tatatattag
    32941 gagatttaga ttcagtagaa gaagaaaaga taaatttcta taaaaataaa ggtgttaaat
    33001 ttgaaaaatt tccatctaaa aaagatgaga ctgatacaga gctttgtctt tttttagcta
    33061 agacacttaa agcaaatcat attgattttt ttggtgcttt agggggaagg attgaccaca
    33121 ctcttgcaaa tataaagcta ttatattatt taaaagaaga tggtatatat tctaggatac
    33181 tttctgataa agaagagatg tatatagttg aaaatgagga aatttcattg tatggaaacc
    33241 caggggacac tatttctgta atagctataa atggtgatgc taagggtgta acacttactg
    33301 gcttagaata ccctctcgat aattattata tgaaatactc tgtacctatt ggaatatcaa
    33361 atgttatgtt gagtaattct tgtaagatta aagtagagca aggctgtgta cttgtagtta
    33421 gaaatttata aaatttgatt ttgacaattg gttttatatt gtagagcaga tacaatcaag
    33481 taaaatatat ttatgattgt atctgctttt tagtatataa ttataaatat ataataaact
    33541 ttgacataag ggggattttt tgtggtagat agtattattt ttgatttaga tggaacattg
    33601 tgggattcaa ctgaagaagt atgcaaagtc tggcaggatg ttttaagtaa acataaggaa
    33661 atagaattaa gtgtcacaaa agatttattt agaagtctta tggggctttc ttttgaggaa
    33721 atagcaaatc gtttatttcc aaatttaagt gaagaagaaa gaatgaattt attgaatgaa
    33781 tgttctttga aagaatgtga ctatttatct gaaaatggag ctaaattatt tgatgatata
    33841 gaagatactc ttaaattact atctaaaaaa tataaattat ttatagtaag taattgtcaa
    33901 gctggatata tagaatcttt tttaaaagca cataaactag aacagtattt tatagatttt
    33961 gaatgtcctg gtaatactgg tttgcataaa ggagaaaata ataaacttat aattgaaaga
    34021 aataaattaa taaatccaat ctatgttggt gatacgcaag gtgatgcaaa tagtgctaag
    34081 tttgtaggta taccttttat atatgccaaa tatgggtttg ggaatgtaga tgtatatgat
    34141 tattttatag actcatttaa agatttgtta gaacatgata tattaaaata agatgagttt
    34201 aaaaattata ttaaaataat aaaaaagtta tggggggatt taaaaatgga attacaagat
    34261 actattttta aaagacaaag tgtaagaaag tttaaaaatc aagatgtatc agatgaagat
    34321 attttaaaaa tgataaaagc agcaggtgca gcaccatcag gcaagaatat tcaaaactgg
    34381 cattttgttg ttataaaacg ccgtgattta atggaaaaga tagcagatgt gataactaaa
    34441 aagcaacaag aaatacttgc agaaatggat aaagtatcag tggataaggc taatagattt
    34501 agaaaatttg ttaaaaactt tacactattt tatttaaaag ctccagtttt agtattagtt
    34561 tttacaaagg tatataaccc atcaggatat tatgaattag agcttataga tgcacctaag
    34621 gagactatag ataaattatt tataagaaat ccaggtatgc agagtctagg tgctgcaatt
    34681 gaaaacttta cactatcagc aattgaactt ggatatggtt cttgttggtt gacaagtcaa
    34741 aactatgcag cagatgagat agaagctgtt ttagaagcag aaactggttt tgaaaaggga
    34801 gagtattttt taggtgcaat gttagctctt ggagtgccag aggacaattt gaagagtcca
    34861 tctaaaaaac cagtagaaga aatatgtaca tttataaaat aaaagtcaag gacattttaa
    34921 aatcgaagta aattaaaaac aaaataaatt aaaaataaat atttaaaaaa ttaaaaagta
    34981 ggttttattg atattaattt tatatttcaa atcattgatt taattaatac aataagaact
    35041 actttttttt gtatattaat tttaaatata tttaaatctt tagaaaatct ttagaaaagt
    35101 atatgtaata tcttaagttt ttaattttaa tattaagtat ataaaacaaa atgaaaaaat
    35161 attaaattta aactagaagg aggtttctaa gatggacatt aaatacaaat aaccagaaca
    35221 aaagatataa atatatatat aaatggaaaa acttctatca tattgtataa tcatatatgt
    35281 aaagaaaatt tataaattaa tataaaggag attagaatga attcatataa tattttggtg
    35341 gtagaagatg aaaaggagat agcagatgct atagaaatat atctattaaa tcaaggatat
    35401 aatgttttta agggatacaa tggattagaa ggtcttaagg ttatagaaaa ccaagaaata
    35461 catttagcta tagttgatat aatgatgcct aaaatggatg gtataacact tacaatgaag
    35521 cttagagaaa actataattt tccagtaata atgctatctg caaaatcaga ggaagttgac
    35581 aaaataatgg ggcttaatat aggagcagac gattatgtaa caaaaccttt taagccatta
    35641 gaactattgg ctagagttaa ttcacaactt agaaggtaca ctaagtatct aaacatggtt
    35701 ggaaataaag agcaaaaggt agaaagtgac gatagtgtgt ttgcaatagg cggattagaa
    35761 ttaaatgaaa atacaaaaga agttagtatt gatggaaagt atataaaaac aactcctata
    35821 gaatttaaaa tactaagttt acttatgaga aatgcaggaa gagttttttc tgctgatgaa
    35881 atatatgaaa gagtttggaa tgagaatgct gtaaatacag atacagttat ggtacatgtg
    35941 aggaatataa gggaaaagat agaaattgac ccaaaaaatc ctaaatattt aaaggtggtg
    36001 tggggtgttg gatacaaaat tgaaaaaatt taaagataaa tatatagtta ctattatagt
    36061 ttttatactt atgttatcag catcattagg tatgattagt caatattcta ctatacaagc
    36121 aagtgctaaa ggtggagcag agaatccatt tgaacaggaa agctttgtag atagtatata
    36181 taaaggaagt tatgttttat atcataatat gaaggaagaa caagaaggta agatgataca
    36241 accatcaaag ctatttatca atgaagaaac tatgaactat ataaaaaatg taagtaaaga
    36301 aaaagatact tatgatggtt cagaaactta ctatacagat gatagtatta atgcagattt
    36361 taatgaaaac tttgaaaatt gggagcattt cattaaagcg tcaggaaaga atttaaagta
    36421 ctatttagtt gataaagaaa gcaattttga attttttaat gataataaag aattaggagt
    36481 acttgataca acaaagaatg atgcttcaaa agaaaattct gatgaaaatc agtcaaaaaa
    36541 tacagaaatg aatgatgagg aaagacaaaa gcagattaca gatataaaag aaaactatag
    36601 attctacgtt gtaatgaatt ttgataaaga tggaaaagta aatattgtag attcttatgg
    36661 agtaaatcaa aaagttatta atcaaatgtt gttatctaaa gcaagagaag atttaatgga
    36721 tacaagttta ggaggaaatt caatttcata taagttatct ccaataaaaa atataacatt
    36781 agtatatgct gtacctaaag caataagtaa aggtgatagt gtagagtatg gttatggaaa
    36841 tacttatttt gatgatggta taatttcata tataagcaat gtagaaaata attcttatta
    36901 taagatttct ggaatgattt taaaaattat attagctata gttgttattg tagctttagc
    36961 attcccatat agaaaatcta aagagttgct aggatttgat acattatcaa gaataccgtt
    37021 agagatactc tttattgctc ttgctattat acaggggctt gtagatttat atcctactgt
    37081 tataataagt aataccttga gtgggaatta tgtagagtac cttataaaca atgacataag
    37141 tgctaaaatg gctagcatat tggtaagttt aatgaattta acttattggt ttgtaatatt
    37201 ctcaataata tttgtattta taatactttt aaaacacatt ttaaatgttg gaataagaga
    37261 gtattttaca aaacatacta tgacaggaat gttttttgta tggctaaaaa aagcaggaaa
    37321 aacagttatt aatcaaatta gaacaataaa tctaaaagaa aagccaaata aaactatagt
    37381 tacaattttg ggaataaatt tattgattat agttataatg tgtagtatgt ggttctttgg
    37441 aataatactc gcattaatat attcagtagt attatttaag atactgtcag attactctaa
    37501 aaagacaata tatgaatata atcaactttt agatgttaca aagaaaattt cagatggaaa
    37561 cttagatgta aatatggaaa aagatttagg attttttaat cctataaaag acgaattagg
    37621 aaatattcaa actggattta aaaaagctgt tgacgaagag gttaagagtc aaaagatgaa
    37681 aacagagctt atatcaaatg tatcacatga cttaaaaaca cctctaacat ctataatcac
    37741 ttatatagat ttattaaaag atgaaagtat aacagatgaa aatcgtaagt tgtatattga
    37801 tacattagac agaaagtcac aaagattgca acatctaata gaagatttgt ttgaagtaag
    37861 caaggcaaat agtggagatg tttatttgaa tatagtaaat gtggatattg tatctctaat
    37921 gaagcagaca cttttagaat tagatgacaa acttgcagat tcatctctaa tagtaaagaa
    37981 taacttttct aatgaaaaaa taatattacc attagatagt cagcgtacat ttagagtatt
    38041 tgaaaatctt ataataaata taagcaaata tgcaatgcca aattcaagag tgtatattga
    38101 tattttagaa acagataata aagtaaatat tatgcttaaa aatatgtctg catctgagat
    38161 tgattttagt gtagatgata taatggagag atttgtaaga ggagataaat cacgtaacac
    38221 agaaggttct ggtcttggtt tagcgatagc aaaaagtttt atagaattac agggtggtaa
    38281 gatgaatata agtgtggatg gtgatttatt taaagttaca attactttta acaaaaatta
    38341 gattagactt atttaataat tataaagtct atagaataaa agagtctgga aatatttatg
    38401 tgtattcttt aaataaaaat ttataggtat tgttttaaaa taatttgtaa gcattatttc
    38461 aaaacagctt ataaatgtta ttttaaaaca gaatgttgat ttatttaaaa aaggtgaatc
    38521 ctaatataca aggttcacct ttttatttta caaaatgtta tttagtgtta cagagcttat
    38581 aaatagcata atatctgggt ttactattaa catagtacta gcaatttatt ttgaaatctt
    38641 gtataagcta ttttatatta tttaattact attgtttgta ctttacaatg tgataaagaa
    38701 tttacctcta cagttttagt atttacttta agcttgctag tattatcata gatttcgtcg
    38761 agcattgcac tataagcatc attgacattt ttattgatgt taagacttcc cttagcatcc
    38821 tcatttttca taccattgaa gattctaact acaattccat ctcctttttc ttctttcttt
    38881 attgcactta ctgtgaaatt tgaattattt acattcatca aactatattc attttcatat
    38941 atttgttttt cgtcattgaa tgcaaatata agtctaccat ttaaaaaatc agcatattca
    39001 tatatttgta taggtgttaa gaatctctta gctgtattag ctacatttgc ttcatcaaat
    39061 ttattgttat atatgtaaag accaaagtca aagtttaact ctttaagtaa ttgtgcatct
    39121 ggtgttgcta ttattttttc tccagaagct cttcctggtc tataaagtaa attttctctt
    39181 cccatatatc caaatgacct gaatagtgtt aatgctattg tatctaaatt atcaccaact
    39241 atttgatatt ctcttacaca accagttatt aatgctattc ctctttgtcc atcctctaaa
    39301 gtaacaaaac tttgcattgg ttcgatagtt ataggttttt cttgccatga gtaattgtct
    39361 cttttccaca atgcaaggtc tttttctaat actgttggtc tttgtattat tccaaattgt
    39421 tgatctgcta tagaaaactt agatgctatt tctgtattaa ataaaactct tactctatga
    39481 gatagtgctt ggttattttt tatattaaca ttaaacttaa ttatttgttc tttaggttct
    39541 aaggtaattt tcattgttac tggcattttc acagaaactt tacctatagc cctttcttcc
    39601 agtgaagctg gtatggtcaa tgaatattta agtatcattt cttcttgaat gtttgatttt
    39661 agcacttcta ctgaagatac agaatctaaa gatgaaacat aaatatcttt tcttggagga
    39721 gaatagttgt atgaatctcc atcatctcca ttatcttcaa ttacagcttg gtttttataa
    39781 gtcttattag attctttatc taatatttct aatgaaccat ttttattggc tgttattttg
    39841 tagtatttgt tttctatttc tttgcaatta cttgtttcta tttcacattt atttttagta
    39901 tccaattcaa aaactagttg agtatatccc attggtggta tatcttttac tgaaagtgca
    39961 atttttgctc tatatacagt tttgggtata tatatttttt tacttgggtt taatcttatt
    40021 gtttgagtta atatataatt tgtaatatct tctttttctt ttattatata attaagaatt
    40081 tctccatttt tattctttat cacaaaatct tgacctggaa tataagtatc aaattctaca
    40141 acttcatttc tgacttctgg gaatccattg aatactgtta atgttatttc ttcattatta
    40201 tttttgattt gagtacttat aagtctcata tgcaaatcta ataaatttat actcaaatct
    40261 ctggcttgtt tgtatcttgt gtatacatcc tcatttgttg tgtcactatt acaagaacct
    40321 atgctgtcat gagctgcatt ttcaaacata agtttccata tatcttttat aactagatga
    40381 gggtattcat ttccaagtga ataacttaat gttaataatg gttcaagtac atttgtaata
    40441 taattttcta atttgttatt cattatttta aggtctgacc ttgaggagaa tatggatttg
    40501 tgtattctca tatgtttagc atttaaaaat tcacctttaa gctctgtaaa ttcatttctt
    40561 tcatttctta ctgaatctat atagttttct atatcactta tttcgtattc attttcatta
    40621 tctatttcat tagctttttt taatatatca ggaaggtttt ttcttattgg tgcttggtca
    40681 aatccatttg gaaaatatac gttattagta gaagctttaa ccttaagttt tccgattata
    40741 tcttttaaat attcttttaa atctgaatca tcttctggta tattacctcc atagtaataa
    40801 ccaaatggta tttgaactgc taatactttt gaaccatcag aacctttcca tataaactct
    40861 gttgtatcta ccatatcatc agaaactcca cgccaaaata atgaactatc tattccaaaa
    40921 cctctgtata tttgtggcat ttgagctgat tgcccaaaag aatctggtac atatccaacc
    40981 ctcataggtt caccaaattc attgcatcta tctattccat agtaaaggtt tctaattata
    41041 gattctcctg atataaccaa ttggtctgtt tgagtatacc aaggtccaat aactaatctt
    41101 cttctttgaa ctaaatctct tattctatat tcatcctgag gtctccattt taaataatca
    41161 tctaagagag aagcttgtgc atccatagta aagtatttaa agtcttcttt ttcttccaat
    41221 atgtctaata tatcttgaaa atctttcatt aaatatattt ttgaccttga tgttgtaaaa
    41281 taccattctc tatcccaatg actgtgtgga actacatgta cttttgtctt tttcataaaa
    41341 atcctcccaa aatttaattg agaattgaga gtacactcaa ttctcaatta tctaaaatta
    41401 agtttttaat ttacattata tctaactcta tttcatcaaa ttctatattt tccgtagttt
    41461 catcttcatt gaagtctact aaagttgttg atagtattgc tattactaaa gctccaaata
    41521 ttgcacctac taagtaagcc catccagaac ctattgatat aaatccatat aatccaccaa
    41581 ctggaggcat tatagcatgt acacctaaca aagctgataa tcctacaccc aaagcgcatc
    41641 ctatcatatt aacaggaact aattttaatg gatttgttaa agtgaaagga attgcacctt
    41701 ctgttattcc aattataccc ataactatat tgccttttcc tgtttcagct aatgcattgg
    41761 aaaattttga ttttcttatg aatgtagcta aaccatatcc tagtggaggt ataactattg
    41821 cgcagtttac caatatcgct ggtagataga ttccctctaa caataatgca tttcctgcca
    41881 tccaagctgc tttatttact ggtccaccta aatcgaatcc tatcattgcg cctaaaatta
    41941 aagccaatac caccgaattt gttccatttt gacacatttc agctacccaa gcatttaatg
    42001 aagtatttat gtttcctaaa ggtcctgcta atacaacact cattaaaaaa ccagttaatc
    42061 caactgttat aagtggcatt attataagtg gcatcattcc tgatgctgac ccagatattt
    42121 taattttttt ctttaaaaac ttacaaacat acccagcaaa gaaacctgct attactgctc
    42181 ctaagaatcc tgcattagta ttacttgcta tgagcccacc aataaaacct gcacccatag
    42241 ctggtttctc acctattgaa aatgctataa atcctgctaa taccgtattt aatagaccta
    42301 tgccagtcca accaacttgt tccattaagt aaagaatatg ataaaaacca gatacatttt
    42361 tataagcatc taaacttgtt atacccactg ctaaagctgt aagctttggg atagctacaa
    42421 ctaaagatga gcctattaca agtggcaaca tatatgagat acctgtcatt aagtgtccct
    42481 taagttcact taaaagagat ttattttttt tactcatttt taatcctcct atataagttt
    42541 gttatatttt ttgataatat gttataatta tattagacaa ttttttaatt tttgattttt
    42601 ctcattctat attagagtga gattttttta ttaagaaata gcttctatac actttgttaa
    42661 gacagcttct ggttttttta acgctatacc tattttgact tttatcactt ttttaccatc
    42721 aaatctttcc attccagata tagtttggtc agatgctata agtataaagt ccgcatcttg
    42781 tgcttcttct tttgttatag tatttactcg tcccatagca ccttgttgtt ctactttgat
    42841 ttcatgaccc atttttgatg cagcttgttc taaagctttt gctgccatag gtgtgtgtgc
    42901 taatcctgct atacatgatg ttattgctac tattttcata attattcctc cttcatttta
    42961 ttagttatat attttactaa atgacttgca tcactagcat ttttaacttc acttgtaaaa
    43021 tcatcctcca ttaaacatgt ggctaattta gatagagttt tcaaatgtat atttccttca
    43081 tttttatgtg gggctaacaa actaaataca tatctaacct tactatcatc taaagttttc
    43141 cactctaact cgttagttgt tttaatatag agtatggaag cttcctttac atttacactc
    43201 tttgtatgag gtatcgcaaa tccatctttt attcctgttg gaaattcatt ttctcttttt
    43261 agaaggtctt ttaaaagagc ctctttatta gttgtaatac ctagtatata agcactatct
    43321 gcaataaaat ttaatacttc ttctttgctt tttaagtctt tatctataaa tatatatttt
    43381 tcttgtagta ccatatattt ttccactcca ttcataatgt cttaacttat atttatattg
    43441 taatcattat cctaattaaa ttaaatataa ctaatttcca cttcgacatg gaaatttata
    43501 ttatgataat aactaatttc catatagaag tggaaataaa ttattataat acaattttat
    43561 tagagtaatt gtattatatt agtgtaaata gtataattta gaagaaattc tataaggggg
    43621 gatatttatg cacaagagat tgctcacgtt gtttaaatta ttaaatgaaa gtgatgataa
    43681 aattacttgt aaaactttaa gtaatcattt aaaagtgagt gagagaacta taagaaatga
    43741 tattacttct ataaatggaa ctttagagaa aaatggtgct attattaaaa taaaaaaagg
    43801 agaaggatat tatatagata ttcttaattt agcattatac caacagtatc tagcattaat
    43861 atctgatgat attatggatt caagtgaaat accagattct cctatagaaa gaaatcaata
    43921 tattttaaaa tatattctct ataacaatac atatataaaa ctagaagatt tagctaatag
    43981 cttgtatgtg agtaaattta caatactaaa tgacataaaa agaataaagc ctattttgtc
    44041 aaagtataat ttaatattag tttctaagcc atattatgga gttaaagttg aagggaagga
    44101 aatagatatt cgaagatgta tttctaataa tatgataaat aggaattttg aaaactatat
    44161 aattggaatt acagatagag aaatagaatt atttaataat gtagatttaa tagagcttca
    44221 aagggtagtg ttaagtgaaa ttaataaatt taatatcaat ttcctagatt ttaatctaaa
    44281 aaactttatt atccatttag ctattactgt aagtagaata cttgatggtt actgcttaga
    44341 taatgtttta gatgttgttt taacagattt tcaatcgaat acaactgttg aaaatatatt
    44401 taattatatt gagagcaaat atactataat tatttcaaag gcagacagag tttatctata
    44461 taatcatttt ataactaaaa gttctctttt ggataacgtt tccaataggg tagatactaa
    44521 aattatagag tatgttgaag aaattttaga agtaatcaac aatcaatata cttttgacct
    44581 tagaaatgat agtgtattat ttgatgattt agtactgcac tttaaatcaa ttctcaattc
    44641 taaatcttat aatttaaata aggtgaatcc ccttataaat acaataaaga gtaattatcc
    44701 tttagcattt gaaataactt taaatgctat agaaaaagtt tttaaaaata gtatttactc
    44761 tttaacagaa gatgaaattg gatatgtatc cctgcatata ggtgctggaa tagagagatt
    44821 ttttcaaagt aatattaagt gtaaaaacgt agtattagta tgtggttcag ggtatggttc
    44881 aagtaggtta ttagaggttc aattaaacaa agtttttcat gataaaataa atatacttca
    44941 atgtctatca tttaatcaat ttttagctag tgaattgtca gatgtagata taataatatc
    45001 gacaattcct ttaaatcatg atagtattcc tattgtatta gtggatttaa aactattaaa
    45061 aaaagatata gagaatatat ctaagtcaat cactaataat tcccatattt atagtaatct
    45121 tttggacaat ttctttgata aaaatttatt tattgttaat cctaaaatca aagataaaga
    45181 tgagcttata aagttgatgt gcaacaaatt aactcaaagt gaaattgtat ttccatcatt
    45241 tgctgaatct gtattttaca gagaaagttt atcttctacc aatatagatg attttttagc
    45301 tatacctcat cctatggaat taagctctat aagaactaag atttgtattt ccatattgga
    45361 tgaaccaata tattggagtg aagattctac tgttaaatta atcatgatgt tggctataaa
    45421 taaagatgat tatataaaaa taaactccat ttatgatatc cttttaaaga taattcatga
    45481 caatgatatt agagatagta tatctaattg taatgatttt gataattttc tttccataat
    45541 caagtctata gtatagattt ttatattaca taagttttaa aaactttaat aaaatatttt
    45601 ttgtttttag cataaatagt ataagtaagt tttgtataat ttgttattat tttgtattga
    45661 ttataattat tatacaataa agattctgtc tcaaaataga gagagaaacc tgtttttcat
    45721 tgataaaatg ataaaaatat atctgatttc atacaaaaaa gagtgtctca tgaactaaaa
    45781 agttcatttt gagacaccac ctttattatt ttatattatt tatctcttgt atatattact
    45841 atagcatccc ttaaaaactt agctaatcca ggttgttctc tatcataata tgatgtaaaa
    45901 cgttcatcat atacatacat ctgtgctaga gaggaatgag cttctttaga gtatgtgttc
    45961 caagtgtaac tcaaccattt atgatgtaat tttgcaactt cctgagccag ttcactagag
    46021 gcatcaccag ttttaaaagc ttttttaagt ttactaatta tttcgatatt taggttttgc
    46081 caattttcat aatcttgctt agacatattt ttaagttttt tgtttgatgt atctataata
    46141 tctttaccat atttctctct aatttcagtt ccataatttt tttcattttc atcaatcatc
    46201 ttttctttaa aaccttcaaa tttttctata tctgtcatag tgtattttcc ctccttcaga
    46261 gctatagttt tagttacatt ttctattagt aaatcaattt gctttctttt ggctagtaat
    46321 ttattatggt gttcttttaa cgcacttaaa ctatcgaagt ttggtgaatt tataatgttt
    46381 tttatatttt ctaagttaat tcctaattct ctataaaaaa gtatttgttg aagtttatta
    46441 acttcatttt gaccatatat acgataacct gaagaattta ttttaagtgg tttaagaaga
    46501 cctatttcat cataatatct aagtgttcta gtacttatac cagctagttt acttaatttt
    46561 tgaactgtat attccataag tagtacctcc tataaattaa atatacactt ttacgcaacg
    46621 taaatgtcaa tacattaaaa tataaaaatt tatatctttt aataaaaata taaaaaaata
    46681 tctttactgg atattttaca cacaactgtc aatactcact aatgaaaatt aaaaaataaa
    46741 atttatagac tatctttact aaaaaataga gggtctatag tctaggagga actgtatgaa
    46801 tttaaaaaga agcaatgaaa aacgagaaga gtacagaaga atgtattcag ataaagaaag
    46861 ttttttaagt ttgattcaaa attttacaag tgtctcaata gcaaaagaat taactcttaa
    46921 aaatatagag ttagaaacat cttttatatg tgaatataaa ggaaaagaag ttgatataat
    46981 ttataaggta ttttctaaaa gcggcaaagt atcacattat atagtgttag aatttcaaac
    47041 agaaatggat actgaaattg tcccaagatt gaaatcgtat agagaacaaa tttggaaaag
    47101 ttttattatg aaaaaaagcc ttgaagaaat agaagataaa aattttaaac ttcctaaagt
    47161 tataccagtt gttttatata gtggacctga aaggttaagt agaaaaaaag gaattttgga
    47221 tattgtagaa tctatatcgg agttcagtaa taattctagt atgaaaaatt aaaattacat
    47281 aatgtgttta ttggtctaaa atggaaaact gtcgcataaa cttgaatatg aaaatattta
    47341 tagatacagg ttctatgtgg aggtgttcca tgagaaataa caagtctaag gtattgctag
    47401 gaatactttg tctagcaaca ggaatggctg taattctgtc aatgttgctt cctggctgga
    47461 tttggtcagc acttaccgca ttaatactta ttggatgtgg agcattatta tttttttgtt
    47521 aaaatagttt taactataaa gtgtggggtg agtattgatg aaagtagtaa caataaaatt
    47581 accaaaatgg atttcaagta taatcctaaa atttatgaga aagagtaaaa atgattaaat
    47641 taaaaagcct acttacggaa gtaggctttt aaacgtggtt actaagctct ttcaatttta
    47701 ccagaacgta aacatctagt acaaactttt actctcttag gagctccatc tataatcgct
    47761 cttacgcttc ttaagttagc tgaccatgtt cttttattat gtttatttga gtgtgatact
    47821 tggtttccag aaaccttacc tttaccacat acgctacata cttttgccat ctacgcacac
    47881 ctccttaaaa tgataactat ttaaagacta aaaacatatt tatattatca taaataacaa
    47941 aaatttgcaa tagaaatata tatttgcctt acacatattg aagaatttct tattatcata
    48001 taaaattata tatataattt tatataaagt aaatatattt ggaaaataat tattattttt
    48061 ctttgaatat atatactata gaagaaattt tatccaaaaa cttttctagg tttaaattat
    48121 accatattta tagtatgata tgattataat tttatataat aaataagtaa aaatagtaaa
    48181 aaataaatta agaaatgttt ttaataaaaa taagcttaag ggggtcaacc atgagtgcaa
    48241 aggtaacgaa tcaatatgga aatatagaaa tagataatca agtaatagct caagtcgtat
    48301 atagagctgc aatggaaagt tatggcttag taggtttagc atataagtct aaaggaatag
    48361 tagagctatt aaaaggcgag aacgcaacta aaggtgtaag agttgaggaa gtagaagaag
    48421 atgccatagc aatcgaactt tatgttataa tacaatatgg tacaaatata tctactgttg
    48481 ccaataatat aatagataga gtaaaatatg tagttgaaaa aatgactggc gtaagagtta
    48541 ctagaattga tattaatgta caaggaataa gagttaagta atttcatagg aggaaacaaa
    48601 tgattcaata tatagatggt aaaaggttaa gggagatgtt tatttcaggt gcaaacaatc
    48661 tccaaaacaa taaagagtta gttgacaagt taaatgtatt ccctgtacca gatggagata
    48721 caggaactaa tatgtcatta acaatatctt atgccttaaa agaattagca aaagttgaaa
    48781 atgataatat atcagatatc ggaaaagcat tatctaaagg ttctttaatg ggagctagag
    48841 gaaactcagg agttatactt tcacaaataa tcagaggtat agctaaatct atagaaggaa
    48901 aaagtaaatt atcaacagaa gatttagcaa aagcttttaa aaatggttca gacacagcat
    48961 ataaagctgt aataaaacca attgaaggaa ctatacttac tgtagttaga gaaagtggag
    49021 agtttgcaat aaaaactgcg aaaaaagaga aagatgtagt aaagttttta agtatgcttg
    49081 tgaaggaatc aaattcttca ttagaaagaa ctccagacct tctaaagaat ctaaaagaag
    49141 ctggtgtggt tgactctggt ggaaagggtc ttgtacttat atatgaagga atgttagctt
    49201 ctataaaagg cgataacata gaaataaaaa atgttgacct agatactaat atttcaacaa
    49261 gtatggattt tacaaagagt actactagca cagatgatat aaaatattgc tattgtacag
    49321 aatttatttt agaaagttct aaggtagaag atactaaaat aagagacata atgatggctt
    49381 atggtgatag cctagcagta gttggagatg atggagtcat aaaggtacat gtacacacta
    49441 atgacccagg aaatgtactt caagaagctc taaagtacgg tcaattatta actataaaaa
    49501 tagaaaatat gaagttacaa catgaaaata cattactgga tgtagaagaa aagaaagaaa
    49561 atgatagtga acctttagaa gaagaaaaag agtttgggtt tatagctact tctatgggtg
    49621 aaggtttggc aaatatattt aaagatttcg gagttgacca tataatagaa ggtggtcaaa
    49681 ctatgaatcc aagtactgaa gattttatga atgctataaa gcatataaat gctaaaaata
    49741 tatttatttt cccaaataac agcaatataa taatggctgc taatcaggca aaagaattga
    49801 gtgataaaaa tataatagtt atacctacaa aaaatacgcc tcaaggattt gctgcattag
    49861 taacttttaa tggagaatta agtgaagatg aaaataaaga agctatgatg aatgctttaa
    49921 actcagttaa atcaggtcaa gtaacttttg ctgttaggga tacagtgatg aacgaaattg
    49981 atgttaaaga aggtaatata attggaattg cagaagggaa tttattatca gcaggagatt
    50041 atgtggatga agtaacatca aaccttattg aaaagttggt tgatgaagat actgctataa
    50101 taacattatt ctttggtgaa gatgttacag aatctcaagc aaatgaacta cgtacttctt
    50161 tagaagaaaa gtttgaagat gtagatgtag agttatatta tggaggacaa cctctttatt
    50221 attacttaat ttcagttgaa taatgattat aagaacctgt atgaccaagt agcttttata
    50281 aaattggttg tacaggattt ttgtgtagta ggtgatatat ttgttggatt tatataaaga
    50341 tgttcaatat gttaagggaa taggacctaa aaaagcagat aaattaaata aactgggtat
    50401 atttacacta aaagacctat tgtattattt tccaagacaa tttgaagata gaaataatct
    50461 aaagaaaata gcacaattag aagatggtga gaaagttacg ataaaagcag taatatcaag
    50521 tataaataca tttagcccaa aagaaggtat gactttaaca aagattgatg taaaagatga
    50581 gacaggctcg gctaaattag tgttttttaa taagagttat ataaaaaata cttttcgtcc
    50641 aggagattca atattagttt ttgggaaggt taagaaaaaa tttaataact tagaacttac
    50701 atcatgtgaa ttagaatatc ttactaattc acctaagaat acatgtagat ttatgcctgt
    50761 gtaccagctt acatacggtg ttacaaataa agaaattatg agtataatta gaacagtact
    50821 tgaagataaa gaattaatta tacaagaata tatgccacaa agaattatag aaaaatatag
    50881 gctatgtagt atagattttg cagttagaaa catacattca ccaagtagta aggaatcatt
    50941 aaaaatagct ttatatagaa ttgtatttga agaattactt atactacaac tagggttgtt
    51001 tgtatttaaa agtggcagaa ataaagaaga tggaataaag tttgaaacaa gtaaagactt
    51061 aaaaaaaata ataagtgctt taccatttaa actgactaaa gctcaaaaca gggcattaga
    51121 tgaaattata caagatatga atttagagaa aataatgaat agattggtac aaggtgatgt
    51181 agggagtggt aaaacagtag tagctctctt agcacttgca aattgtgttt taaatggtta
    51241 tcagggcgct ttgatggcac ctacagagat attagcaggg caacattata tttcacttac
    51301 tgagtctcta aaagattttg gaataaatgt aggtctatta ataggtagtc ttacaaaaaa
    51361 acaaaaggat acagtattgg aacaaataaa gaataatgag attgatatat taataggtac
    51421 acatgcacta attgaagata aggttgaatt taataatatt ggtttagtta taacagatga
    51481 acaacataga tttggtgtta tgcaaaggag caaactttca ttgaaaggag caaatcctga
    51541 tatattagta atgacagcaa caccaatacc aagaacttta gcacttatac tctatggaga
    51601 tttagatatt tctattatag atgaacttcc tccaggaaga cagccaatag aaacaattgc
    51661 tattgaaaaa agtaagcgag atagagcata taataacctt gtaagaagag aggttgaatc
    51721 aggaagacaa gtgtacattg tatgtccctt ggtagaagaa agtgaagcca tagaagccaa
    51781 atcagcagtt gaacttgttg aggagttaag agcagaatat tttcacgact taaggcttgg
    51841 gttgcttcat ggtaaaatga agtcaagtga aaaagatgaa gtaatgagac tttttaaaaa
    51901 taaagaaata gatattttag tttcaacaac agtaatagaa gttggtgtca atgtgccaaa
    51961 tgcaacatta atgataatag aaaatgcaga aagatttgga cttgcacaat tacatcagct
    52021 tagagggcga gttggaagag gtagtcataa atcgtattgt gtactaattt atgattctaa
    52081 aacagatgta tgtagacaaa gaatggctat aatggaagag accaatgatg gttttaagat
    52141 ttcagagaag gatttagaaa taagaggacc tggggaattt tttgggacaa ggcagcatgg
    52201 tcttccagaa cttaaggtag caaacttgtt taagcatata aaaatactga agttagcaca
    52261 gcaagaagct cgatatatat tgggtgaaga taataatcta caattaaaag aaaacatggc
    52321 actcaaaaaa gaaattatag ataaatttaa agatacattg aaagaaattt cattaaatta
    52381 attttaaatt gtgttaaaat attactaatg taataatgtg ctgaagggag attgtcatat
    52441 tgagagtaat ttcaggaaaa gcgagaggat taaaactaaa tactccaaaa aatgaagatg
    52501 taaggccaac tacagataga gtaaaagagt ctctatttaa tatgataaat tcatatataa
    52561 tggaaagtga agttctggat ttatttgctg ggactggttc tttaggaata gagtgcttat
    52621 ctaggggtgc caagtcatgt acttttgtag atatcagtaa ggaaagcata gatattgtta
    52681 agtccaatat aaaaaaggca agagttgaaa gtgaaagtat tattttaaac cttgatttta
    52741 agactgcaat agataaactt aaattacaaa atagtaaatt tgacataatt tttatggacc
    52801 ctccgtatta taaaaatatg tttatagaag ctattgaaaa aattgataat tctaatctat
    52861 tgaacgaaga tggaataata gttgtagaac atgatacgaa tgatttattt ccagataaga
    52921 tatgtaaatt ggagaaaact agagataaga aatatggaaa tactacatta actttttata
    52981 agatggaggc ataatatgga aaataaacct agaaaagcta tatttgcagg aagttttgac
    53041 ccaattacta atggacattt agatattatt tgcagggctt cgaagttatt tgacgaatta
    53101 caaataggag tattaaataa tcctaataaa aagggtctat ttagctttga tgaaagagta
    53161 aaacttatag aaaaaagtac aagccattta aataatataa aagttgtgac ttttgatggt
    53221 ttattaataa attactgtca ggaaaatggg attggagcat tagttagagg tgtgagaagt
    53281 ggtgctgatg ttgattatga acttcagatg gcacatatga atagagagct taatccagat
    53341 atagagacta taattttacc aagttgtaca aaatattcat ttataagttc atctttaata
    53401 aaagaggttt tgctctttga tgctgatata aaaaatttgg ttccaaagat tgttttggaa
    53461 gaattaaaga aaaaaactag tgggggtaat tgatatatga agatagattt agaaatgatt
    53521 gaactatttg agcagttaga ggagatattt agaagtgctt ctacaatccc tttctcacat
    53581 aaatgcacag tggataaaga tgaggtttta gcaataatta atgatataag aactttaata
    53641 ccagaagaag taacacaggc agtatggatt aataaagaaa gaaataaaat aataagtcaa
    53701 gctaagcaag atgctacaaa tatagttgaa caagcgaaaa aagaagctga gagaatacaa
    53761 caagaatatc aagataatat agaggaatta aagaaaaatt ctgaagatgt agtaaaggca
    53821 tatgtagaat ccagcgaacc tgttgttcaa gcagaccaaa gagcaaaaga tatagttgat
    53881 agagctgaga gaatagccaa tgagataaga attgggtcaa ttgaatatgc agaggatgtg
    53941 ctttctagtg ttgagtataa tttaagagaa atattagaag aagtaaaaag agataaagct
    54001 gaacttagac ctaaaaaata aattttaaat aaataaaaat ggagctatca cacaaaaaat
    54061 tccaatttat gtgtgatagc tctcttttaa tatagcaatt ttttgttata taattgtgct
    54121 ttttagatta cttatatctt attttgatat tataatgtag tttaatcttt tatttgttga
    54181 aatcaactta tttatttgta taaataatat aggttatttt caaatttttt taataatttt
    54241 accactgtct tcttttagat tagagttaga ctgtgcaaaa ttataaaata atactaaatc
    54301 atgtgcaatt atttggtatg gcactacatg tagaaaatat agataataaa attaaggagg
    54361 tagtatgaag gaaagggcta aaaaaatatt agattttatt attaaaaata acaatgtaac
    54421 atcacaagaa ctacaagaaa agtttaatgt ttcaaagaga actatttatt acgatattct
    54481 agctataaat aaacaactag gaaaaagtgg taatataaaa aatgtaaaac acaaatttat
    54541 atttgaaggt aatttatgtg atgcaaggaa aataatttca actgaagaag ataaattttt
    54601 agatagtgat tacagaaaaa cttttatatt aaacaagata ttacttggcg aaaaaatatc
    54661 aatagaaaaa ctaacaaatg aaatgttact ttcaaaaaac acagtagtac aaacaataac
    54721 tgatgtaaaa aaataccttc aaacaatggg attaagatta gagtataagg gaaagtacaa
    54781 aattataggt gatgaatacg ttattagaga gctgtttctg ataattgttc aagaaaacgt
    54841 actggaaatt aattctataa gtgaggaagt aagtagtttc gatacaaaag gacatataaa
    54901 acttactgat tattctttat taaatctaac taagtttgtg gaatttctaa ataaaaggat
    54961 aagagatggg aaaacattat actcatataa atatctaaat gaagctaaaa aaattagtta
    55021 ctttagtaat tgtaaagaac ttttatgtga agaagctaat gaaaatgaac aagcctatat
    55081 atgcacttac ataagctcac ttcccagctt aaatagtgaa gttaaggaag atgttgttga
    55141 agaatatgta gataaactta tagataagtt tgaagtaaat acagcaataa aattagaaag
    55201 taagcatgag tttaagaaaa atattttaag gcacctccac tcttcttaca acagaatacg
    55261 atttaagttt cctattagaa atccaatgtt agatgagact aagtataaac atgagtcact
    55321 ttataaaatt ataaaatcaa ttatagagaa tgaagaagag tttcctgtat ttgaggggat
    55381 aagagaagaa gaaataggat ttatagcagc gtattttgga ggatatttaa gagggtctag
    55441 ggataatggt ctaagaagaa ataaagtctt actagtttgt cctaatggtc ttatggtatc
    55501 aaagagtttg gaaatacaac tatataaata cataccaacc atagaaatag taggtatagt
    55561 atccattaag caactaaaag aagtaaatgt atactacgat tacataatta caactataga
    55621 tatacaaaat gtaaacaacg taattgttgt aaatcctctt ttaacatcat cagatgttca
    55681 attacttatg aacaaactaa taagtgtaaa agaaaacgag aagtatttca atcttgaatt
    55741 aataatacaa gctataagaa aaaatggagt tatcaataat gaagaagcac taaaagctga
    55801 tttattaaac ataatacaca agatagatga aggagagatg tatcaaccaa tgttaaagga
    55861 attaattaat gcagaaaggg tcaatataat aaaaaatgtt agagattgga aagaagcaat
    55921 aaaaatagcc tcaaagccat tgttagaaga taactctata gaagagttat atatagaaaa
    55981 tatgataaag tcagttgaga aatatggacc atatattgtt ttagctgata gatttgctct
    56041 accacatgca agttctaaag aaggagtaaa caagcttgct atgtctttac taatagtaga
    56101 agatgaagtt gatttattag gaaaaccagt aaatatattt atggtattag ctgctgtaga
    56161 taacactact cacattagag cattagcatc actatcagag atgatgtacg aggaagaaaa
    56221 tgtaaaacta ataattaatg gtgataaaag ttcaatacta gaacttataa ataagcaaaa
    56281 ttaggaggaa tgaaaaatga agatattagc agtatgtggt tttggtgtag gttcatcaat
    56341 ggtattaaaa atgacaatac aaaaggctct aaagcagtta ggtatagaat gtgaagtaga
    56401 aaatacagat ataaattcag ctagaggtgc tgattgtgac tgtatattca caagtcaaga
    56461 attgttaaat gaattaaaag gaacttgtaa tgtagatgta tatccagtta aaaagtacat
    56521 ggatttagca gaagtcacag aagttgttca aactttttta agtgataaaa atgataagaa
    56581 atagtataag ttttaaaaag taaatttaag ttaatcagaa taaaataaaa acttactaag
    56641 ttcaaaaata gtaagaaaga gaggagggat ttagtggtag aaaacttaaa cagttgactt
    56701 atcactaaaa aatataatgc ttgattttat ttcaaataat attttacgta atccatctat
    56761 gttaattgga ttaatagcag catttggtct tgtactacag aagaagaaag catctgatgt
    56821 tataaagggg tcactacttg cagctttcgg aattataatt atggagactg gaacaggtat
    56881 gttagttagt tcaatagcac caattaatgg agctttccaa agtataagtg gtggtgcagt
    56941 aacaaaaggt ttaagtgatg ttacttttac tgcaagttat ggtggaatta taggtttagc
    57001 aatgtttgcg ggtttagcta ttcacctaat gatagcaaga tttactccta ttaagacaat
    57061 cttcttaaca ggtcacatgc tttattggtt cccattcata tttgtagctt caggagttga
    57121 agctggatta aatggtggag tattaatagc ttttgcagca gtattatcag cactctattg
    57181 gtcaataatg ccttggttat taagaaaata tgtgtttgat gttataggag atgattcttt
    57241 tacattaggt catccatctg gttgtttagc acttatatca ggatttgttg ctaaattagt
    57301 aggaaataaa gaaaaatcta cagaagatat aaacatacct caaagtttat cattttttag
    57361 agaaatatct ataagtggtg gaatggcagt gtttttaatg tttatagttg ttgggatagt
    57421 aataccaggt gcgtttaaag atagtaatga gtttattgga acgtatgcaa taaagcaagg
    57481 tctttctttt ggagcaggtc ttataataat gcttcatggg gtaagaatgc taataaatca
    57541 aataatgcca gcatttcaag gtatatctga aaaagttgtg ccaaatgcac tacctgcttt
    57601 tgactgtcca atattattta attataaacc aaatgctgta ttaataggat tcttagttgc
    57661 tatgctaaca tctacagcta tgattttaat atgtaactac tttaatgtat ttaatttgct
    57721 acttatacca cttgttataa cttcattctt tgagtgtgga gcagcagcag taataggaga
    57781 atcacaaggt ggtatacgtg gagctataat aggtacagct atagctgcaa tatttatggt
    57841 agttttagta ggaatatctg ctgtaattta ctcaggaact attcaaaatt ggatactaat
    57901 atttggaggt aatgaccttt cattatttgg tataatcagt aggtttatag gttcactatt
    57961 tggaggaata ttatagatat gaaatttaaa tacatagatg agataagaag attaattgat
    58021 ataatagaaa acgaagaaaa agtcaatatg gaaaaagcag tacaaatcct tgttgaagca
    58081 atagaaagta aaaatgctat attttcattt ggagcttcac atgcaggaat attaacagaa
    58141 gaattattct atagagcagg tggctgtgtt cttataaatc cagtatttgc aaaatctcta
    58201 atgttagata cagcacctat aactcacaca agtaagatgg aaagattaga aggatatggt
    58261 acagctctag ctgataaaac tccaattaaa aaaggagatg tagttatagt tcattcagta
    58321 tctggtagaa atccagtaag tatagagttt gctatgaaag ctaaggaaaa taaggcaata
    58381 gtaatatgta taactaattt aagttactca aaaagtgtat cttcaagaca ttcttcagga
    58441 aaaaaacttt atgaagtatg cgatttagtg atagataatc atggtcaaaa gggagatgcc
    58501 tgtgtagaga tagatggatt aaaccaaaaa gttagtccaa cttctactgt aatagcaact
    58561 actgtgatga actctattat agctcaagct actcaggaat tagttaataa agggctaaag
    58621 aatcctccga ttttctatag tgccaatatt gatggtggag atgagttaaa taagaagatt
    58681 tttgatgaat ataaaagtgt aattcattat gaatattaag gttaaaaaaa tatgttaatg
    58741 aactttgaag tttatcaaca aagaatatta ataatatata ataaatgcta tcatttaaaa
    58801 gctgtaggta aaaatctaca gctttttatt attgtagatt aaaaagatgc gtaattaaat
    58861 tttaaattgg agaaaataaa ttggaaggta tcaattataa atattagaaa cgttgtcata
    58921 gaaaaaaact atattaaaaa aaagtacata gaaaaaactg attagacaat aaatacatgc
    58981 tttgataata ttttaaatgg agtgaaaatg tgtagaatta taatgaaaaa agaaaataaa
    59041 aatgaaaaaa gaaaataaaa tggagggaat aaaagtgggt atgttaaaaa aattatgttc
    59101 actagctatg gtagcaatta tgactacaac acttataaca gggtgttcaa gtggaaatgg
    59161 aaaagattca aaaaaggatg gcgaaaaaga aaaactagtt ctttggatgc caccagtaga
    59221 aaataatatg aaggaagttt gggaccctat tttagataaa tttgaggaaa aaaataactg
    59281 tgaagtagat ttacagataa ttccttggga taattattct gaaaaatttg caacagctat
    59341 aagtgctggc gaaggtccag atgtaggata tatgtatgca gaaatgtatc cacagtttat
    59401 agaaagtgga gcagtagaag atttgactaa ctatgcaact aaagaggata aagagcaatc
    59461 tatttatata aaaacatctg aaatgatggg tggaatgtat ggtatgccat tccaagcagc
    59521 aaatccaggg gtattatact ataacaagga tattttagag aaattaggag aaaaacctcc
    59581 taaaacatgg gaagatttta aaagaatttg taaaaaagca acgcaagata ctgatggtga
    59641 tggaaagata gaccaatggg gattagctca gggatgggga gctaaaactt ttggtaactt
    59701 aaactggaac tggtatcctt atttatggca agctggtgga gatatattta atgatgattt
    59761 aaaatcggtt aaatttaatg ataagagtgg tttagaagca gctaagttct taaaagaatt
    59821 acaagcatat gtgcctgaag attctttatc taaagatagt aatgaaatga tagaaagtgt
    59881 atttggacca gggaaagcag catttacaat aatgttatct tctgctgcaa caagtgtatt
    59941 tgatgaatca ttcccggatt taaattgggg atttgtaact ggactagaag ataagaaagc
    60001 agcaactttt ggagcagtag accatttatc tttaatgtca tctgcgaaaa ataaagaact
    60061 tgcatacaag ttaatacaac atatgttaag tgttgaatca atgacagaat ttcataaagc
    60121 aataccaaga gcaccaataa caaaaggtga accatatcaa ggtgatgaaa gattcaaaga
    60181 aatggtggaa aatgacaaaa atgtatatag accattagta gtaggacctc atggagttga
    60241 aatatatgaa tatttatgga aagaacttca aactatgatt tcaggagata aaactccaaa
    60301 acaagcgtta gatgatgctg caaaatattc aaatgattta ttagcacaat aaaagtttaa
    60361 agctgtaata tgttgtaaag gactttacag attaaaatta gcattgtatt tataaataca
    60421 atgctaatat ttatattgga gaggataaaa tggaaaactt agttagagag tttgaagaaa
    60481 attcaaaaag aaaaaaaaca aaattaaata ttaaaccata tatgtatata ttgccattgg
    60541 gaataatttt agtggcgttt tatgtgatac caataataat gtcaatatac tttagtttta
    60601 caaagtataa tattattagt ccagctactt ttataggttt agaaaattat aaaaaattat
    60661 ttacagatga aacattaaaa gtatctatta taaatactat taaatttact gttgttgtag
    60721 taccttgcca aactatatta tcattgattt tggctgtttg gattacagga aaaggaaata
    60781 gtaaaatagc ttcatttgct aaaggtgcta tatttatacc agtattatca tctatggttt
    60841 tgataggtat ggtatggagg gctttattga atggagaagg ttctattata tatcaggtat
    60901 taggtgcctt tggaatagaa tcatctaaac ttttaggaga tagtaagaca gcattaccta
    60961 cacttatgtt tatatctatg tggaaaaata tagggtattt catggtaatt tatatttcag
    61021 ctataatgaa tttaccaaaa cactgctatg aagtagcgaa ggttgatggg gctacaaaac
    61081 ttcaagaatt tataaaaata actgtacctt tattaaaacc aactacaata atggttgtat
    61141 ttttagggtc gatatggtca ttacaagtat ttgacttaat ttatactgtg acaggtggag
    61201 gtccaggtat atctactatg agtatagtta tgcatgcatt taacttaaac tttaaaaact
    61261 ttaattctgg atatgcaatg actgtagcaa acgtattatt tttgttaata gcagtagttt
    61321 cgattttaca aaataagctt gtaagacgag acaattcaga tttttagaaa ggtaggtata
    61381 atatgaaaac agcaagaaga ttattaagtg atggtttact tttatttata gcgtgtgcaa
    61441 gtttggtacc ttttatatac atgttgataa tatcattgaa gataacatat aactcatata
    61501 gtttggatat atctttttca acagtaaccc ttcaaaacta tatagatatt tttactaaaa
    61561 aaggatttgc acaatatttt tttaatacag caatagtatc tttttcaggt gtattattaa
    61621 atttagtatt tagtacatta gcaggatatt cttttgcgaa gatggatttt aaaggtagtg
    61681 ataagttatt tttatttatg ataatgactt taattatacc ttcccaagtt acaatgatac
    61741 cactatatat aataatgaaa cacttaggat ggataaatag ttatcttgca cttattatgc
    61801 caataccaac tgcatttggc gtatttataa tgagacaagc tattttagga gtaccaaaag
    61861 agttattaga atcagcaaag atagatggtt gctcggattt tagaatttta atacaaatag
    61921 tgttgccttt aattaaacca gcattaatta cactagcaat atttactttt atgggagcat
    61981 ggaacgagtt tatgtggcct cttatagcta caactaaaga tgcaatgaga acattaacag
    62041 ttggattatc tactcttaag acattccaga taactaatta tggacagatg atggcagggg
    62101 ctacaataac atttttaccg ccatttattt tctatttgat tttgcagagt aaatttgttg
    62161 aaggtgtgtc tttgtctggt ataaaaggtt aaatagtcta atttaataat atataaagaa
    62221 acttatataa atatggagga atttaaacta tggaaatttc atatgtactg aaagattgca
    62281 cattcaaaca caataaatat tcagttatag aagctgaaac ttggaaagat aaggatttgg
    62341 atattgtagt agctaaaggt gaaaaatttg catttcaaat tatgttaaaa gcaacagaag
    62401 aatttaattg tacaattgat aaaagcagtg ctatatcatg gaaaggccta ggaaatagag
    62461 taaggttagc attaaatgtg cctaatagtt tagaaaataa ttttagtata aatatattag
    62521 gatatgttca agatgataca aaggcatttg tgaatgatgc tattttaagg gataaagatg
    62581 tgttagtaga gcaatatttg cctcaaacat tttggattga aggtcaagta ccagaagatt
    62641 ttgaagaaaa taaccttgat ataggtattg atatatttaa aagctttgga tatgaagacg
    62701 aagaaaaagt ttgtacaatt gatgttcctg taaaagtaag aaatgttgtg ctaaagcctt
    62761 tagatgaaag caagttcttt ttagatttat ggcaacatcc aagttgttta gctagaatgt
    62821 ataaagttga gttatggtct gatatacatt ttgaaatagt cgataactat ttaaaagaat
    62881 tagcatcttt aggagaaaaa gttgcaacag ttatagtttc agattatcca tgggcagggc
    62941 aaagttgtta taaagtttat aaaaatccat caaacttata tgaatataac atggtaagtg
    63001 tatcaaaagg attggatgga aagattaaat gtaactttga gagtatggat aggtatatag
    63061 gcatagctga taagtataaa atggctaagg agatagattt atttggtcta ttaggtaatt
    63121 ggtgtgctgg tgagtttgga aatcctgtag aaggttataa ggaccctata agagtaagat
    63181 attttgatga aaaggataaa gtatttaaat ttataaacaa tacaaatgat ttaaaagaat
    63241 atataggatt agtattaaat catttaatag agtgtggatt atgggacaga gtaaggatta
    63301 tagctgatga accaaataat ccagaagtag tcaaagagtg tatagaattt ataaattcta
    63361 ctgtaggtac tcatcaagtt aaatataaat cagcaactca cgaccaaaac tttttagaca
    63421 gagctaaaga tgaaattgat gatatgtcaa taaatttaaa acttactata caaaattata
    63481 aagatataga aagtcttaag aaaaaaatca atgacaaggg tgggatattg acttggtttg
    63541 tatgctgttt tccagagaaa ccaaatagtt ttttaagttc tccttttgta gaaaatagaa
    63601 taataggatg gtatacttat tactttggtc ttgatggatt tttaagatgg gactataatt
    63661 tatggacaga agacccttgg aaagattcaa gttacaaatt ccctatttgg aaagctggag
    63721 atatgttctt tgtttatcct ggaaaagatt taaagccagt tagaagtgtc agaatggaga
    63781 atttaagatt tggaatacag gactttgagt tatttacaat gttagaaaaa gaaaagggaa
    63841 gagagtatat agaagttgag cttatgcaag aattattaaa taaaaaagaa aatgctgaaa
    63901 ttaaaggttt tggtgacata gaactaggat attcacttga taattgggga tatgataaag
    63961 ttaaaaaata tgtattagag ttgttagaca gagtataaaa aatataagag tgtctcaaaa
    64021 tgaacttttt agttcatgag gcactctttt tgtatgaaat caatatagtt tcattgtttc
    64081 aacaatgaaa aataggatta tttctattct aagacagccc tttagttttt tagttgtatt
    64141 caatgtttta aaactaacta taaacgctat aaagtttata aatgacaata attatatata
    64201 acatgatgta ctttaatttg ctataatagg gattgaataa tattatatgg aagataacat
    64261 tgtttggggg gattaatata aaaagaatag gtattattat aatgtttttt ttaagtatat
    64321 cttttattgg attttatctt gtaataagag ataacagtga tacagttaag atgcaacgag
    64381 ggataaatat aggtaatgca ctagaatcac ctaaggattt tccgtgggat gtaaaaatgt
    64441 caaataagtt ttttgatgat ataaaagatg caggttttga cacagtacgt ataccagtaa
    64501 ggttttctga ttatacgtca gattctgata attttaaaat tgatgaagaa ttttttaaaa
    64561 agattgataa atatgtagat tatgcattgg ataaagactt aatagttgtg ttggatttac
    64621 accattttga agaaattatg aaagaaccaa gagttcataa agaaaagttt ttaaaaatat
    64681 ggcaacagat agctaatagg tatcaaaaat atgataaaaa attggtattt gaattattaa
    64741 atgaacctaa agaaaattta tattcacagt tactaaacga atacattgaa gaagcaataa
    64801 agataattag aaaaactaac cctaaaagaa ctattatagt aggaccatat aatttctatc
    64861 aaattgatta tttgaatgaa ttaaatattc ctaaagattc taatatagta gtttcctttc
    64921 actattacga gccaaatgat tttgcatttc aaggaaatat ctatcataag ggatttgagc
    64981 acttaagcaa tattacttgg gaaggaacaa atgaacaaat ggattattta aaaaaaaggt
    65041 ttgatactgt ggaaaattgg gcaaataaaa ataaggtaaa aatcttcttg ggtgaatttg
    65101 gagtaacaaa agaagcacca gaaacttcaa ggagagcttg ggtaaaagct gtaagagaag
    65161 aagctgaaaa acgaaacttt tcatgggctt attgggagct tgcttctgga tttggtatat
    65221 acaatcaaat tgaagggact tgggatagag aaatattaag tgcattaata gaaaagaggt
    65281 gattttatga agaaaaattc aaaaaagata cttataactt taactattat tactaatata
    65341 gtatatatat tgtggagaat tttttataca gtacctaaag aagaagggat gtttgcccta
    65401 atctgtgcca taatacttct ttttgtagag ataatgggta tgatggaaat gtttgtgcat
    65461 tattatggta tgtcaaatat tgagtaccct gaaaaaccaa tcataagtga agaactttat
    65521 ccacatgtag atgtattcat tgcaacatat aatgaatctg ttgatttggt gagaaaaact
    65581 gtaaatgggt gtattcatat gcagtatcca gataagaaaa aggtacatat atacatatgt
    65641 gatgatggaa atcgtgaaga aatgtgtatt ctagcagaaa aaatgggtgt aaattacata
    65701 actagaactg aaagagaagg agcaaaagct ggaaatttaa ataatgcaat gcaacataca
    65761 aattcccctt tgattgctac atttgatgca gatatgatac caatgcatga ctttttaatt
    65821 gctacagtac catacttttt gaaaaatgag caagctaaaa aagatggaga aaaagaggag
    65881 tatgaaaagg ttggttttgt gcaaactcca cagagttttt ataatccaga cttgtttcaa
    65941 tttaatctgc actctgaagg aaggattcca aatgagcaag attattttta cagagacatt
    66001 caattggcta gaaataggac aaattctgta atttatggtg gtagtaatac agttatttca
    66061 agggaagcac ttgaagaagt tgatggattt tatacttatt ctattacaga agattttgca
    66121 acaggtatct taattcaaag taaggggtat agatgttatg ctattccaga agtacatgca
    66181 tcaggtttat ctccgacaga tttaaaaagt cttattaagc aacgtgaaag atgggcacgt
    66241 ggatgtatac aaactggtag acgtctaaat attttgttta ggagaggttt aggtttttgg
    66301 cagaaaataa gttatatttc ttcaattact tattggtatg caagtataaa acgctttgta
    66361 tatataatgg cacctatttt attttctgtg tttaatgtga ttgtagtaaa atgtacgtta
    66421 cttcaagtat tggtattttg gttgccaatg tatattttaa gtagtttatc tcttaaaata
    66481 ttttctcaaa atataagaaa tactagatgg accaatatat atgaaactat aatgtttcag
    66541 tctttaatgc cagcagtaat acttgaaacg tttgcaatat ctaaaaataa attttcagta
    66601 acaaataaga gtaaattaga agaaaataga atgtataagt ttttacaggg aataccttat
    66661 tttatttaca tggtcttatc tatcatagga attttaaaaa tgtttgtagc aatatttaaa
    66721 atgagttcaa tgacatattc agttgtatta ttttggttga ttggaaacct ttttaacctt
    66781 gttatggcta cattatttat atcagggaga cagcagttaa gaaagtctga gcgttatatt
    66841 gctgaaattg attttaagtt aaagcaaaat tcttatgttc tttcttcaaa aacaattgat
    66901 atatcagaaa atgggtttgc atttttgcta gaaaatccag aatatatttc cccagaagaa
    66961 gagtttgagg tagagtttag agaaaaatct ggaaatgaaa tgtatatagc taatatgaaa
    67021 gcaaagattg ttaatgttgt ggaagtaaat tcaaagtgga aatatgcagc ttatattaca
    67081 catattgagg atagtgaaat agataattgg atgtgtattg ttcacgatag aatacctact
    67141 ttaccaatga caatatctaa tcaactaggt ttctttgatg atttgcaaat taatgtaaaa
    67201 aaacgtattg aaaaaactag aacattatca cgaagaagtc caagaatcaa tatgaatttt
    67261 cagatggata taaaaaatac aggtaaatta agaatagtga attttaatta tcaatatgta
    67321 ttattaaatt ttgagaataa aagtatttat cctaaagaaa tagcattgga aattaatgaa
    67381 aatattgtgt tagaatgtga tttgtgtgag ggtaaaattg atgaaagagg tatcttatat
    67441 aaagtaaata acattgacag cataatgcaa aatttctttt taagagatga aatgatggat
    67501 tggatattac aaaataagac aattcttgtt tcaaagccta gtgaaaagaa ggaaaaaagt
    67561 atagatgagt ttgaacccat ggaatatatt taggagagat gaaatgaaga ctttaaaagt
    67621 gtttttttgt tctacaaaat atcttatttt ggtgtttatt ttttttataa atactacttt
    67681 tataagttca gcaacaagtg ataaaatttt agatttatcc tttaaaaaga tagagactga
    67741 cttaagttct aagattacat atgaggatac aggtgtaaga atagaaacgg atagttctaa
    67801 aagcgataag gaacgttatt tatatattta ccaaaatata aaagaaaatt ggagcatgta
    67861 taataatttt tatattgaaa ttcaaaataa aaataaaagt tctcagagaa taaatttaag
    67921 catacaaagt aaaaatatgc ttgaatttag attaaaagaa ggtagtgaag tatttttaga
    67981 aggtaaaaat ataatatatt cagataaaat aaaagaagga tgcatagaag taccaggtga
    68041 atttgaaggc aaaatttatg tgaactttaa tagccttata aatgaggaaa gtaatgttgt
    68101 gctggactca aatatgcttt caaacattgt tagttgggga attacgttta ttccatctga
    68161 tgaagaacat aatattgtta ttataaaaaa gatatcttta ttgtctgaag agaaattaag
    68221 atttttaaat aatattaaaa taattggcga tgaagaagta caaataccag tattgggtca
    68281 aagtataagt cagtatgaag tattaggtct taaaagtgat tctaaaatta agtactctct
    68341 tatgggaaaa caagataatg tgagcatatc tcaaaaaggt aaattaacat taagtaataa
    68401 agccaaacct ggacaaatta ttttacaagt taatgttgat gataagttta aaattggaaa
    68461 gaaaataaca ttaactgagt cttggagtgt taataaaaaa gataaggatg gtgttccata
    68521 tacattagta tatcctgagc aatcaccaac agtacaagat atgaaaaaaa taaactttat
    68581 gaataacatc ataacgtttg ttcgaatttt atttgtatct ctagtaataa tatgctttgg
    68641 aatatattta tattggaaaa aatgttcaaa aactaagtaa agagaggagg ttagattgtg
    68701 ttattttcaa gtttaatttt tttattttat tttttaccta taactttggt tttatattat
    68761 gtatttaggt ttaaccgaac gatacagaac atgatattgc ttgctgttag tttatttttt
    68821 tatgcttggg gagagccaaa atttgttgtt atcatgatag tttccataat aatgaactat
    68881 atatttggtt tactggtaga tagatatagg gaaagtaaaa taaaagtaaa agttttttta
    68941 gttttgatgt gtgcatacaa tataggtgtt ttatttatat ttaaatatct agcttttgcg
    69001 ctaagaaata ttagtgaact tattagtact gaattgacta tacctagtat tgttttaccc
    69061 ataggaattt cattttttac atttcaggga atgtcttatg ttatagatgt atatcgtaga
    69121 catggagaag tccaaaagaa ccctttttat gtgggattgt atatagcatt tttcccacaa
    69181 ttaatagcag gtcctatagt tagatatgag agtgtggcag aacaaattct caatagaaaa
    69241 gaaacttgga ataaattttc tattggtact tgtaggttta taacaggtct aggtaaaaaa
    69301 gtattaattt caaataacat ggctatagta gcagactata tttacactat gaatagtcaa
    69361 ggagaaatag ctgcatcact tgcatggctt ggttcaatag cctatactct gcaaatattc
    69421 tttgattttt ctgcttattc agatatggct ataggcttag gtcttatgtt tggttttaaa
    69481 tttgaagaga actttaatta tccatatata tcaaaatcaa ttagtgagtt ttggagaaga
    69541 tggcacattt ctttgggaat gtggtttaag agctatatat actttccgct tggaggttct
    69601 agagtagcaa ataaagatat tatgattaga aatatgttta tagtgtggtt attcactgga
    69661 atatggcatg gagcagaatg gacatttgta atttggggga ttttaaactt tgttttccta
    69721 attatagagc gatttataat gtttgaaaag attgaaaatc acaattttat aaaacatatt
    69781 tatgctttat tagtagttaa ttttggatgg gtattgttta ggtcacctaa tttaaaagaa
    69841 gcatataatt attttaaagc tatgtttgga ggcaatggag ctatatggag tgattataca
    69901 tatatgtttt taaaagaata ctgggttttc tttatatttg catttatttt tagtgtacct
    69961 attgcaaaga aaatcaataa gtttgttgtt gaacaagcta aatatagtat gatatttaac
    70021 gtattttatc caatctcagc tattttattg ttttttattt ctgtgacata tttagtaact
    70081 ggaagctata atccatttat ttattttaat ttttagttgg gaggaaaagt atgaatagat
    70141 tttttaaagt aagattaata actgcaatta tgttcttaat tattttattc gctttctcta
    70201 tctttaatgt ttgttattct ggaaaagata cgatacagga aataaaaaat tcaatagctg
    70261 aaaaaagtag tttaaaagat acaatatcat ctattgataa tacagtgaat gacaaagtaa
    70321 tatacaaaaa tacgttcatt gaaacttatg gctatttaca aaaattaatg ggtaaaaatg
    70381 agttttcaaa atttagtgtt gtaaaagata cttctggaaa gatgcattat acatattttg
    70441 ctaaagctcc aaatccagtt ggtgtgatag cagatagggt aagaaaattt tctgatgaaa
    70501 tggaaaagca aaacactaaa ttggtttacc taatgactcc agataagtat ataaaaggag
    70561 tgacaaaatt tcccaaagga ataccttatt cttatagtaa tgagacagca gataattttt
    70621 taaatcaact aaaaaagtat aatgtggact atattgattt tagagaaaat attttaaaga
    70681 gtggtattcc aaaagatgat ttatttttta aaacagacca tcactggaaa gtagaaactt
    70741 ctttttgggc atttggagaa ttagttgagc aacttaataa aaaatacaat atgaatttag
    70801 atgaaaatca ttattataga gataaggaca attataattc aattgtatat cctaagtcat
    70861 ttcttggttc tatgggaaga aagactggta tcttatatgg tggtatagat gattttacat
    70921 taatttatcc taaatttaag actaattata cttattatac agattctaaa tctcaaaaat
    70981 ttgaattaaa aggaaggttt gaagagagtt taatattatc atatcctttt aatgcagacc
    71041 ttaatttaat ggatggtcaa tcagataagt attttacata tttattgggg aacagaccat
    71101 tagttaaaat aaaaaatata gaaaatccag atggattaaa agtgctgttt gttaaagatt
    71161 ctctaattgt accaacagca gcattttttt cctctgtttg ttcatctata gatatgatag
    71221 accctagata ttatgatgga gatatactag aatatgcaaa atcccatgac tatgactttg
    71281 tttttatatc tgtatatccc caaaatctta caaaagaatt ttttccgttt tgtgagtaaa
    71341 tttctaaaaa agttttctga taaaataaat ggctaactgg taaaaagtta gccatttatt
    71401 ttgagtgtta ttctaagaaa tatttttttt actaaatact tctttatcta tttttccaag
    71461 tgattttcct acagtaattg atgataccat agcaccatta acatttatca tagtacgtcc
    71521 catatctagt atagggtcta ttgcaagtat accaccaact aatggaaaat aagaaccaag
    71581 accaactcca gagataacaa ctgaaacggc cattgtagca gttcctggaa gaccagctat
    71641 tccaaacgaa ctaattgtta taacaattaa caacataaca taaaagctca tatccatgtt
    71701 tactccagcc atattggcaa gtgttacagc cattaaagca ggatatatac ctgcacaacc
    71761 attcataccc atatttgcac ctaaacttgc tgtaaagctt gatacaccct catcaactcc
    71821 gtgattttgt actagacttt ctatcgttac aggcaatgtt cctaaactag aacgtgaagt
    71881 aaatgccaga agtaaagctt cagttgaatt ttttatataa gtaatgggat ttagaccatt
    71941 taaagttata aaaattaaat gtatgataaa taatattgca actgatatat aaagagctaa
    72001 tataaactgt aaaacagata ctattgaact aataccttgt gaagttattg tatttgcaag
    72061 cagagcaacc acagcataag gcataaattt aataacagtc atagacacac ttacaattat
    72121 tttgtaagat gcttctataa aatctataaa tggttttatt gtctcaaaat gttttttact
    72181 taatctcttt attgaggtag ctataaatgt agcaaatatt attgtagcta caatatttcc
    72241 atttgccata gccattacag gattagatgg tagtaatcct cttaaagtat ccacaagaga
    72301 gtttatttct ttaagttctt gattttcaac taaagtaggc atattagctc ctacacctaa
    72361 cttcattata tttgcaacga taattccaac aattgcagct atagcagtag tagcaagaag
    72421 catacctaaa gatttaaatg tcagagttcc aagattgtta tctttcatat ttataattac
    72481 ttttataatg gataagaaaa ctaaaggtac tactaacatt tttaataagt ccataaatcc
    72541 agaaccaaat aggctatacc acttacttac ttcttgtagc caaatgactt gagttgtatc
    72601 attagggaaa ccagcaaaag cttgtattat gattcccaat atgagtccta gtactgtagc
    72661 atatattgtt ctcaatgaaa attttatttt tttcttttca aattgtctaa caataaagaa
    72721 cgtacctaga agtaatatta tgaaaaaaat tgttttaaaa tctgtaatca taagaaattg
    72781 tgataaaaat gaactttcca atatttttct ccttttattt aaaaataaat ttttctaagt
    72841 ttaaatgata tcaatatatt aaaaaaatgt caatattata tcacaattta cttaaataga
    72901 gtaaaacaag ttgattttga aaaatgtgat taagtacaga aaaatagggt ataataaatg
    72961 tttaaagaat ttgaattgtg gtaagaaaat aaaaaatagc ttttataaga tttgatttca
    73021 aattaaaatg tgttaaataa ataactaaaa attattataa aaaatgtttt catagaatat
    73081 atatcaaatg aaaagcttaa aataagtgaa gaaattaact agacatcaaa ggagagataa
    73141 aatgagagta ataataattg gtggtgttgc agctggtatg agtgctgcag caaaattaaa
    73201 aagaataaaa cctgagtatg aagttgttgt ttatgaaaaa actgaaatag tatcttttgg
    73261 tgcttgtgga ttaccatact ttgttggtgg attttttaat gatgctgatg aattattagc
    73321 aagaacacca gagaaactta gagaagctgg aattgattta aatatattta gagaagtcgt
    73381 tgaggttgat agtgaatcta agaaaataaa agtaaaaaac ataaaaacag atgaaatata
    73441 tgaagattac tatgataaat tgatgatagc aactggagca agaagtatta tgccttctat
    73501 aaaaaacata aaattgaaga atgtttctac attaaaaagt ttatatgatg gagaatatct
    73561 aaaaaaactt ttaagtaatg aagataataa aagagtgaca ataataggag ctggttttat
    73621 agggttagaa gcagttgagg catgtaagaa attaggtaaa gatgtagatg taattcagtt
    73681 agaagataga atattgccac aagtatttga taaggagatg acggatgtat tagaagaaga
    73741 aataaataga cataatgtta atttgcactt agatgaaatg gttgtagaac tttgtggaga
    73801 agataaagta gaaaaagtta taacaaacaa aggggaaata gatacagatg tagtaataat
    73861 tgctactggc gtgagaccta ataccgagtt tttgtcaaat actaatataa aaatgctaaa
    73921 aaatggagct atagtagttg atgagtatgg aagaacttct gtagaagata tatactctgc
    73981 tggagattgt gcaactataa agaatatagt aagtaatgaa aatgtatatg ttcctttagc
    74041 tactggagct aataaattgg gtaggatagt aggagaaaac ctagcaggaa gagaagtatc
    74101 ttatcaaggt tcactatctt caagctgtat aaaaattatg gatatggagg cagcatcaac
    74161 tggaattaca gaaaggcaag ctaaagattt aggcataaat gtcaaatcta aatttatttc
    74221 tgattataat caaactcatt attatccagg aagaaataaa atatatgtaa agcttattta
    74281 tgatgcagat acaaaagtta ttttaggcgg acaagtggct gggtttaagg atgctgtcca
    74341 aagagcaaat gtattggcag ctgctatctt tggaaaaatg accacaagtc aacttggaat
    74401 gttagattta tgttatgctc caccatttgc aagaacatgg gatgttttaa atgtagctgg
    74461 aaatatatct aaataatatt tagattatag ctaatatagt tgacaagcaa ttaagggaat
    74521 gaatttacct aaactatttt tatcatggta aaattcattc ctaaattttt attccaaatt
    74581 tttattccaa atttttagaa ataaggattc cattaaatta ttcatcaaaa tttaaacgca
    74641 agcttaatct atcttctcca agaatagtat tttcaaaaac attagtagca ttttctaaat
    74701 acatactagg tatgtctaaa gaaggactaa aatgagtcag taaaagttgt ttgacatttc
    74761 caagttttgc aagattagca gcttctctaa aagtcatatg tttgtttcta acagcttttg
    74821 atatatctaa atcatcacca tacatggctt cacatataaa taaatcacta tcttttatga
    74881 aatctggtat tgattctata ggtcttgtat cggttgtaag acttatctta actccctttc
    74941 ttaattctcc taagaccata tctggagtgt attgttttga atctaaaact atattttgac
    75001 cttcttggag tttgttccat aatattttag gaacttcgtt tttagttgcc ttatctatat
    75061 caaatttagg gtttcttcta aaattaaaac tgtatcctaa acactctata gagtgttcta
    75121 aactgattgt tgaaatttct aaatttctta aaactttatt atctaaagaa aaattgcctt
    75181 gagggttttc tataattttt aaagtgtatg gtacatattc tactaaattt ctcatagaac
    75241 gtatacaatc gactattcca actggaccaa ctatagttaa atcacttgta cgaccactat
    75301 tcccaattgt tgataaaagt cctaaaagtc caaatatatg gtcaccatgt aaatgggtta
    75361 tacaaatcaa gtctatatct ttaaagccac atttttttag cttcatagat acctgagtac
    75421 cttcaccaca gtcaattagt atttttctac ctttatagtt tataaataca gaggatagaa
    75481 atctgtttgg cataggtaca tttccaccac atccaagtaa agttaaatct atcatttttt
    75541 cccctttcta aaattaacac aaatctgttg tttgttttta ttatgatatc ctattataat
    75601 tattttaaca ttaaatataa caataaatgt gtatttgagt caagaaatat tgtcaaataa
    75661 agtttttata taacaatgta taaaaatttg gaggacaaaa agtgaaaatt atatttagaa
    75721 gtatttaaag gaggaaaatt taatgaaagt attaaagaaa attactattt tgttattgat
    75781 tacattaact ttagttggtt gtagtaacgg agaagagaaa aaagtggttg aaggttctaa
    75841 gaaaactcaa aattctaaaa aagatgaaca gcctataata gtgcataaag atgcaaatat
    75901 attgaaagat aggtatgagc caccaaaagg atttaaaaga gttgatgtag aaaaaggtag
    75961 ttttgaatca tttcttagga atactaagct aaaaaattat ggagagaaag taaagtatta
    76021 tgatggaaga actaaggaat caaaaggtat ttatgatagt gtatttgatg ttgatattgg
    76081 aaatagagat ttacatcaat gtgcagatgc aattatgctt atgagagcag aatacttgta
    76141 tcagaataaa ctatatgatg aaataagttt tgattttgtt gatggtttta aggcgaagta
    76201 ttcaaaatgg gcacaaggat atagaatttc agtaaaagat agtggttcaa gctggtataa
    76261 agcaactgaa tattcaacat cttatgagag tttcagaaag tttatggata tagtgtttgc
    76321 atattcagga acgttatctc ttgaaaaaga attggagcct gtaaaagttg aggatatgaa
    76381 aataggagat gtgtttatag ttggtggaag tccaggacat gcaagtataa ttatggatat
    76441 ggcagaaaat gaaaagactg gtgaaaaggt atttatgata gcccaaagct atatgcctgc
    76501 acaacaaacg caacttctta ttaatcgtaa aaatccaaat ttgagtcctt ggtatagttt
    76561 agattttgaa ggtgatttga caatacctca atggactttt aaaagagacc agttgaaaag
    76621 attttaaaat aataatttta tataataaaa gaaaaatata gatgtgaaaa aatgtaatta
    76681 gattaaaact aattggatat ggacaaaatt aaattgatag ataaatatta aaaattacac
    76741 taattaatct tactatagtt taatatttat ctaaaaagtt ttatgtaaaa tataaatttt
    76801 atattaaagc taaaactaat ttgaggaggc taatttatat tgaagattag aaggtattta
    76861 attttggtaa ttataattct aattacaaca agtcagagtt ttatttctta tgggctagag
    76921 cgatttgaag aaataaccat ttttcacact aatgatatac atggaagata tgctgaaggt
    76981 gatgaccata tacaaatagg aaatctagcc acattgaaaa aagaaactcc aaactcaatt
    77041 ttagtagatg caggagattg tttgcatgga cttccaatag taaatatgga tagagggaaa
    77101 agtgcaattg aattaattaa atgtgctgga tatgactata ttactcctgg aaatcatgac
    77161 tttaattatg gaaaagatag actgtttgag ttatctaaaa gtgctaattt aggagagaat
    77221 actttaaaat ttttatcatc aaatattttt gaaaatggaa aaaaagtttt tgatagtaat
    77281 gatataaaag aaatagatgg aataaaaata ggattttttg gactctcaac ccaggaaaca
    77341 aagagcaaaa ctggatttaa aaatgtggaa ggattagagt ttaaaaatcc tatagaaagt
    77401 gcaacagaac aagtaaatga attaaaagga aagggtgcca atgtaatagt tgcaatatgt
    77461 catattggta caaatagttt aagtaagcca aatagtatag atatagcaaa tgaggttcaa
    77521 ggaattgatt tgattattga tggacacagc cacactaagt ttgaaaatgg taaacaagtg
    77581 ggtgatacat tgattgtaag tgcaggacaa tatttagaaa atattggcga gataaaacta
    77641 actttggata ctaatgatgt agaaaatata aaaatagaaa ataaatcagt tagattaatt
    77701 ggaaaagaag aagcattaaa gtataagctt gactccgctg taagtaaaaa ggttgatgaa
    77761 ataaaagaac aacaagaaaa aatattagat aaagttatag gggtaactac aaatactcta
    77821 gatggttcat atgaaaatgt aaggacaaaa gaaactaatt tgggtaattt aataagtgac
    77881 attttactag ataaaactaa ggctgatatt tctttattta atggagggaa tattcgagat
    77941 acgatagaaa aaggcaatat aacaagaaga gatattgtag atgtatttcc ttttagcaat
    78001 actatagtta ccaaagaact tacaggagca cagattaaag atgtattgga gcatggagta
    78061 aaactttatc cagaaaaaag ttcagccttt ttgcaagtgg gaggaatttc atattacttt
    78121 aatcctaaac aaaaagaagg cgaaaaaata acaaatattc aaaaagaagg aaagccatta
    78181 gatttaaata aaaagtatgt agttgcaacg aatgattata tagcatcagg tggagatgaa
    78241 tttccttgtt tttcaaaaga gccagtacta aaggaatttg gaaatttaga gagtgcagtc
    78301 attgaatata tagagtacaa aaaagaaata tcaaaaaatg tagatggaag aattggtatt
    78361 aaatctaaag atgagttaat aagcaagaat catgagagtg atttgatatt aagtgaaaat
    78421 gaaaaaaata tcaatgataa tgaagagaat ctatctaata atataaaaag ctctgatagt
    78481 gataaaaata aaagcttaga taaaacaagt gctagagaaa gttctaatct aggaatatct
    78541 aaaagagaag ctaaagaaaa atctcctaaa acaggagatt taggtttttc aaatagtata
    78601 attatattta tagtttcaag tacattgata tgtttattga attttaatca aaaagagtta
    78661 aaggataaaa agtcaaaata aaaattaatg agcaaaaatt agtagatagt aatttaattt
    78721 tagataatag taaacagcaa aggaaattag ttatataaat actaatttcc tttgttttat
    78781 gttttaacat gattactttt aaataaaatt gtattttatg aaaaataatt acactaaatg
    78841 gcatagtatt atggggattt ttagttttta ttcaagtaaa tgaaatcata ttaacaactt
    78901 ctgatatatt tacaaattga taaaaaaatg attttattag tatgatataa tttagctagt
    78961 atatatgatg atggaggata tagggatgaa taatatatta cttttggaag atgacaaatc
    79021 tttaaataga ggaattagtt ttaaattaaa aaaagaagga tacaatgttt ttagtgcatt
    79081 tggtatagaa gaagcaaaaa atattttcgc aaaagaagag atatgcttaa ttatttccga
    79141 tataggtcta cctgatggta gtggttttga cttttgtgag gagattagaa agaaaagtga
    79201 tgtttacata ataatgttga cagctcttga tgaagaggtg gatattgtca caggatatga
    79261 tttaggtgca gatgattata tcacaaagcc ttttagcttg atggtattaa tatcaaaagt
    79321 gaatgcgctt atgaaaagag taaatacagt aaaaaattat actctattag tttgtgatga
    79381 tttattcttt tattatatag aaaataaatt aattataaga acagatgata aggaagaaga
    79441 gataatttta agtaagacag agacaaaact attaaaatat ttgatggaaa attctatgca
    79501 gacattgact aaagagcaac tgttagaatc tttatgggat agtagtggta attttgtaga
    79561 tgataatacg attgcagtaa atataagaag acttagacaa aaggttgaaa aaaatccatc
    79621 tgaacctaaa tatataaaaa cagtaagagg ggttggatat atgtggggag aaaggagtat
    79681 aaaaaaatgc taaaaaatat gaacctcaaa gatggtttaa gtgtgaaaga tgattatata
    79741 atgagaagag ttattgtata ttctgtttta tctgtactaa tagtaaccct tgtatttata
    79801 ctttttgaat atagcagatt acataaattg tatgaacatc aaataaaaaa tactcaaaat
    79861 attgctggaa tattgattga aaaatatcct aatgatgaaa tagatatagt aaattctatt
    79921 tataattctg attatagtaa ggtgtctact ggagaaaagg catttaagaa atttggctat
    79981 ggattggaaa ataaaatgtc aaatgataaa aattttagct tatacttaaa atcttttttt
    80041 aaggaatcat tttttatttt tttaatgatg tttatagtag ttataggtat aatatattat
    80101 tttataagat acataaataa aagattgagt aaaatttatt ttatagtaga taagatgtca
    80161 caagaaaact acttgaagga cactactgag tcagaagaaa ctggttatct agtagaatat
    80221 aatgaatact ttaaagaagg catatttagt aagataaata actgtctata tgagcttaat
    80281 agaagtttaa agataaagtt tattaaatta gaaaaagaaa aagaaagtgt aaaatcatta
    80341 gtaacagata tttcccatca attaaaaact cctttagcat ccttaaaatt atacaataca
    80401 ttacttatag aagaagaatt agaagaagat gaagccaacg agttcttatt aaccaataag
    80461 gcttctataa ataaattaga aaatttaata aattctttag tgaacatatc aaggttagaa
    80521 attagcatga taaacataaa aaaagaagat aatgatataa aaaatactat tctaaatgca
    80581 gtaaaaagtg ttacccctaa ggctaagagc aaaagtataa cattaaattt aaatgaattt
    80641 aacagtagaa ttataccaca tgataaaaag tggactgagg agagtatttt taatgtatta
    80701 gacaatgctg taaagtatac acaggtaaat ggagaaataa atatatctgt agaagaaact
    80761 gctaatttct ttaaaattat aatagaggat aatggcatag ggattgaaaa aaatgagttt
    80821 aataatatat ttaaacgttt ttatagaggt tctgctgatg aaattgaatc tgtagaaggt
    80881 agtggggtag gattgtattt aagtagaaag attttagaag aacaaggtgg aaatattata
    80941 gtttcttcaa aagtaggaat agggagcaag ttttctttgt ttcttacaac tatgtaatat
    81001 taaatgaaag gaaaatgtaa gcctctacat ttattatata agtataaaca gctccagaaa
    81061 taaaaaatta ataaaatatg gagtaatata acttagaatg agaggataat tttatgaaaa
    81121 tactatatac tgaaaattta tcaaagcatt atggaaaagg agaaagctta gtaagagctt
    81181 tggacaatgt tgacttagaa ataaatgaag gtgaatttgt tgcaataata ggaaaatcag
    81241 gttctggaaa aagtacactt ttgcatatga ttggaggtct tgatatacct acatctggga
    81301 aggtgtatat agataataaa aatatattta cattaaaaga agaagaactt gctgtattta
    81361 gaagaagaaa aatagggttt atatttcaaa gctataattt aattccatct cttaatgtat
    81421 gggaaaatgt agtgttgcca atcggtttag atggtagaga agtagatgaa tcttttataa
    81481 aagaactttt aaaatcatta ggacttgaaa ataaacacga cgttttacca aatacattat
    81541 caggtggtca acaacaaagg gtggcaatag caagagcatt agctacaaga ccagctataa
    81601 tacttgctga tgaaccaact ggaaacctag attctaaaac gtctgatgag gttatgagta
    81661 tattaaaatc tatgtctaag aagtacagtc aaactctagt tatgataact catgatgaca
    81721 gtatagccca aatggctgat agagttatat tcatagaaga tggcagggtg tcaaaggttg
    81781 gtgataaaaa tgattaatac tactaaaata gcaaaaagta atttaaagca aaataaatca
    81841 aaaagtattc taataataat tactataata ctttcaacct taatgctttc ttctattgga
    81901 atttatattg ttgatgcagg agcatatcaa aaagaaaaca ctataaagta ttcaggtaat
    81961 tatcaaggta tattagcaaa tgtagatgaa aaacaggctg atatattgag taatcatgca
    82021 gatgttgaat taactggtga aatgaatgga gtaggtgttg aaaaactgga agatgattca
    82081 aatatttctc tagcatacat gaatgaagat gctttgaaat taaatagttt tgaatttatc
    82141 aaaggaaaat tgccatcaaa agagaatgaa attgtgttag atagtggagc tttaaaggca
    82201 cttggttata aaaataaaga tttaggtgaa aagataaaaa tatcttatga tgactataaa
    82261 aatgataaaa aaattgaaaa agagttcatt ataagtggaa tcttaaaaac tagcgaaata
    82321 tctgaagcag gtaaatatta ttatgctatt atatcagaat catatatgag aaatactaga
    82381 gatatgtcac aagaagattt taatatttat gtgaaattta atgataaaag taatttatca
    82441 atagagcaag caaaagaaaa attagataaa attgctaatg atataggact ggatactatt
    82501 aatactgctg taaatgaaaa ttatataaat gctttaaaac cagatatgga aacgattatg
    82561 ggtggagttt ttgtagggtt agtaattgta ttatctagta ttttagtaat atacaatata
    82621 ttttatattt caatagttac aaaggttcaa gaatttggaa aacttagagc aattggtgca
    82681 actaagaaac aaataaaaaa tatagtgttt aaagaagggt tcatattagc cggaatagca
    82741 ataccaatag gaataatttt aggctatgta cttgcaaata ttataataaa atcatttatg
    82801 gatatagatg taaaatcatc acgattacca gttatattat cggttgtggt aataagcttt
    82861 atatctgttg ttttatcact tttaaaacca atgaaagtag catcaaaagt atccattgtt
    82921 gacgcagtaa gatatacagg aaataaaata agtaataaga gtaagagaaa aggatataaa
    82981 aatataaatc taaagagatt atcacatgcc aatttagaaa gaaataaaaa acgtacttac
    83041 atgacattgg catcacttat acttagtgga actatattta taacagtatc aactgcctta
    83101 gaaagttttg atgctgagaa aatggcaaga gaacactttc cttatgatat agaagttaga
    83161 ctatctggtt atgaaatgaa cagtgataaa aatcctaaag ataatttgaa tattttacaa
    83221 atggataatc ctctaagtaa agattttttt aatcaaataa agaacatgga aggaattaaa
    83281 agaatagaat ctgcaagaag tgtaaaaatt ggtatggagg actatgatgt tgaatttaag
    83341 tatgaccttt tacaaagtat aaatgaaaat gatgtaaaat cattaaacaa gaatataata
    83401 gatggaaaaa taaatcttga aagacttcaa actggagatg aaatagtaat tactcatgtt
    83461 gatacagcaa aagaaatggg agtaaaagca ggagataaaa taagattaac tttatatgat
    83521 ggagataaaa agataaaaaa agaatttaaa gttcaagcaa tagctatggg ggttccaagt
    83581 tttggtatag ggaaagattt tatagataga actttgaaat acgattcaac tagtagcttg
    83641 ggaatatata cagaagaagg aaagtatcaa gaaatcaaag atagtatcaa gaagattgct
    83701 aaaaataatg gatttttaga gactgacttt atagatagta gaattgagtc aaataaggct
    83761 actatttcat ttataaagat aatgggatat acgctaacag gcataatagg tgtgattgga
    83821 tttatgaatc ttgtcaacac aatgataact agcatagtta ctagaaaaaa agaacttggt
    83881 atgcttcaag ctattggtct tactaataaa caattagtga aaatgcttaa ttcagaggca
    83941 atgtattaca cttctggaat gatgatagga agtattctat ttggaggtat attagggtat
    84001 attgctgtta tatttctaaa aaagactgga ttatcttatg caacatattc tttgccaata
    84061 gtaccaatct tgttgatgat tgtgtgtatt cttatagctc aatttataac aacttatttg
    84121 ataggacgaa gttttaataa agaatctctt attgatagag taagatacag tgaataaaat
    84181 gcaaatattt atggttagtt taactagcaa aaaacatata aaaaaatata gttaaagaaa
    84241 ttcataatta aataggttaa agcatagtac agagcaaaca atttaaacag atgtttgctc
    84301 tgtattttat tatgtaatca ataatatatc taatatactg atattattca tgttagaaaa
    84361 tgtaccggta caattctaaa aaagtataaa attgtaccat ataaaatgaa aattttgtat
    84421 aataatcgta tagaaaataa ataggagctg atatatatga ataagaagat taattatgca
    84481 ccaggaccaa ctgaaactag ggaaaatgta agattagcaa gagcagaaaa aacaacaaat
    84541 ccagatatag atattgattt tgttgaattt tataaaaaga catgcgagaa gtttggtaat
    84601 ataattggaa caaaaaacga tgtttacata ttgagtggtg aaggaatatt aggtcttgaa
    84661 gcagcatgtg catcacttac agaaaaagga gatagagtac ttgtaattga taatggtata
    84721 tatggagaag gttttaaaga ttttgtaaca atgtatggtg gggagtatgt gcttttttca
    84781 agtgaatata ctaaaagtat agatattgat gaattgaaag catttttaga tgaggatagt
    84841 aattttaaat atgcaacagt agtgcattgt gatactccaa ctggcgtatt aaatgatgta
    84901 agcaaaatat gtccattact taaaaaatat ggaatattaa ctgtagttga ttctgtagca
    84961 ggtatggtag gagaaagatt aagtgtagat gaatctaaaa tagatataat attaggtggt
    85021 tcacaaaaag ctatttctgc accagcagga cttactatag tcggaataag tcaagatgca
    85081 aaaaattgta taaaaaatag aaaaactgat gtaataggtt tttattgtaa tttaaatata
    85141 tgggaaggct attatgaaaa aaaatacttc ccttatacaa tgccaataag tgacataatg
    85201 gggcttgata aagcacttga taatatatta gaagaaggaa tagaaaatgt attaaataga
    85261 catgaaaaga tagcttatag tgttagaaaa tctattgagg aatatggtct agaactattt
    85321 ttagaagaag gatattctaa tacagtcaca gctataaaag ttcctgaaag tataggagct
    85381 ttagaactta ctgattatat gcttaaaaat tataatacac ttgttgcaac atcactaaat
    85441 caatatatgg atactatttt aagaataggt catatgggag agaatgcaaa tctaaataaa
    85501 atagaacatg tactaaatgt tttggataaa agtttaagtg cactaggatt caaaggaaat
    85561 ggaaatttgt taaatttatt taataagtat tatttttaat agataggggg atatagtatg
    85621 gaagttacag ctaagcaaaa atttacaacg aaagacatgg tggaaacctc actattaata
    85681 gcattagtat ttattgcaac taaatttata aacataagat taccaatatc tataaatggt
    85741 gggcttgtgc atttaggaac tgcaatgttg ttcatatcag caataatatt tggaggtaaa
    85801 aaaggtgctt tatcaggggc tattggtatg tcactttttg atttgatatc tgggtggact
    85861 ttatgggcac cgtttacctt tatagttaga ggagttatgg gttatttact tggaaagatt
    85921 gcatgggcaa atggtaataa tgggaataat tttttaatca atgtaatagg aatatgtgtc
    85981 tcatcaattt ggatgctatt tggatattat gtaacagaag ttatacttta tggtaatttt
    86041 atagtacctc ttacttcaat accaggtaat ttaatgcaag tattgatagg tcttataata
    86101 gcgcttccta tttctaaggt attgaaaaac tgtataaaat aaatataaag tgaactaaaa
    86161 tttatgatag cataaattat actgtataat attaggatgg agtacataat taaaaaattt
    86221 tagtatagag gttagttcac aatgttatca gttacaagat attcaatcaa aaatgttcgt
    86281 ttaaagccgt gggtaaagtt tatttggtat tttgagacaa aatcaaatat actgttaaat
    86341 aataagttac ttccgacaga cagtatagat attattctca atctttctga tgttatggaa
    86401 tataaaattg aaaatcaaga ctatactgct agtaatatgc attttaatgg aataagggat
    86461 aaacatggat ttattattca acatggaaat atacgtgtta tagggatttc tttttatcca
    86521 tttggtttat atccattttt aaagatacca atttcagagt ttaacagaca aattgttgac
    86581 ttagaagtag tatcacagct atttgcaaaa aaattggaag agtcattaag tccaacacaa
    86641 tcagtagaaa aaattgtttt atatttagaa gaagtattat tatccatatt agaagaagat
    86701 ttaatttcaa ataaatatgt aaagcttcta aattcattta tatatgttaa tagatatagc
    86761 aatataaagg cattttgtga tgatacaaat ataaatatta aaacattgga aagaatctgt
    86821 ttaaaatata cagggtatac acctaagatt ttaaagagaa tttacagatt taaaatggca
    86881 agtaatcaac ttatttataa ttataaagat gatgaacttt ttgattttat ttatgaaaat
    86941 gagtactatg accaagcaca ctttataaaa gaatttaaaa aattttcagg gacgtcacca
    87001 attaaattta ttggtgagaa taagacgatt aaagaaaata taaagtacag ctatttataa
    87061 ttatactgtc gattttttac aatacctcca atttattttt tgatatgata taggaaaata
    87121 aattggaggt tttacatatg aaaattatta cagaaatagt tgagtttaat gtggaagaaa
    87181 atttatcaaa agaagagttt atagaaattg taaatgactt agaattaaaa tttcattcta
    87241 ttcaatctgg ttttattgat actgagcttt tatatgatga aaagtctcaa aagtggatta
    87301 tgatacaaca ttgggaatct atagaagacc tcaagagtgc ttctagtaaa atgtttaaag
    87361 attcttcaac tgagaaattt agaaaagctt taaagaatca aactgttaag atgaatataa
    87421 taccacaaat taaaagttgg aaattataga actgaatgta aaagatagtt aaatagtatc
    87481 aaactaaatt agccaaataa cattttgtat ttaaattgtt atttggcttt tagtgtttat
    87541 tttaatatga gtgttatata ctagaaaaac caacaaactg ttagagtgtg gattatcata
    87601 atgtcatatt cgggagctaa aagtcttaat actgatttgc caattggtca atccatgcat
    87661 gtccatctgg atatgctgtt attaaagcat ttacaagcca atccctttgc tcttgtgata
    87721 atagtgggac tgttacatcg aagtcttttt gataaccaag cctatctatg tatattgatt
    87781 tgcaaaacaa aaccacttcg ggagccatat atgggatatt atctgatgtt atcagtctgg
    87841 ccttatccat atctcttata attctttgat tttgggaaaa aagaaatttt ccatctttct
    87901 gtggattatg tatcaattca ataaaatcga actgtaactg ttcgtcacac tgtatattca
    87961 ttttatagtt atcatcctcg acttttttta attcaataaa tgagcaatca ggcttaatcg
    88021 caaaaacaca aatttgctct atatgttgct tgttaaggtc gataataggt cgtaataaat
    88081 aattacccaa gggctcatat atatcccatc cttgattaag catatactga atgctctttt
    88141 ctttatctgt gtcagaaatc catatgtcaa tatcactgtg tgggcgaata tgcatattcg
    88201 caaataattc tagggcatat ccaccacata ttgaatatga aaagccacaa tcattaaaaa
    88261 agtttacaca atctttaatt agtttgttca tagcaacctc cttttgcatg tactgaaata
    88321 aattaaattt ttaaaaatac caactaaatg tttgttttgt gtaaatataa aactgccgat
    88381 attaaggcag ttttatattt actatttaga aaatttatta acaaattttt gatattcaca
    88441 cattatctta tcattcataa aagaaatacc cataaaagca gcttgctcac caaacaaagt
    88501 aaaacgttct atcatctgtt gtggattacc tggataaact gttggaatac accatgtgtt
    88561 tagaagaaaa ccaaacattt gagcagcaat ctctggattt ttaacttcca tagaattatc
    88621 ttgatttcct tcttcaatca atgcttttat ccaaggcaca atatcattta taatctcatc
    88681 aaactgcgta gctaaatact taggattacg caatagtgat gatgacatta aaaaaatgtc
    88741 ttgtttattg tgttgttcat aagcatgaag caacctatat tgtaattttt ctaatgcggt
    88801 ctttccttca tcatttttta cctcataccc ataaaatcca tcattataca accgacttgt
    88861 gattgcctta attatttcgt cttttgattt aaagtgatga taaatagcac ctcttgaaag
    88921 gccatctaaa ttatctacaa tgtcttgaat cgttgtctgc tcataccctt tttctaagaa
    88981 taacttatgt gaaatatcaa gtattttttg tatagtatta tcaggttctt tttttcttcc
    89041 caaaaagctc actcctcaaa acaatcattt ggtatgttta tcttagcaaa tacataatga
    89101 tttgtcaatg tgtcttttta gcatgttgaa caggtatatt gccatgcttt cattatttta
    89161 tttttttgcc ttatactgga ctatatttgc agtttcctaa tatatttggc tcatatttaa
    89221 ataccattat ctaaaagcac tattgctgta cgagaggcaa taggcatttt agaagaagga
    89281 ggagttgagt taaagtatac atcataatct cttaagtttt ctttttttgt gtttcctcca
    89341 aactctacca tatcagtatt taatatcgtt ttgtagtttg tattttgaaa ctttgaaata
    89401 tcaactgatt gtattagatt agggtggaaa ttaaatataa ataaatattt gcccttactg
    89461 tacaccaaaa tctttttatc attatccata tgtataagtt catgactatt ttggataaaa
    89521 atatcactgt attttgtaag ttcgagcata gatttatcaa aatttaataa ttgtttatac
    89581 tttaagttgt tatcttctga aaggctccat tgtcttctgg catacttata gctccaattg
    89641 ttgccttctc gtggaaaatc aatccactca ggatgtccaa attcatttcc cataaaattt
    89701 agatatcctt cacctgctag agaaaaagtt attaatttaa ttaatttaat aagagatatt
    89761 gctctattga taacatggtt atttgagttt atttccatat tccagtacat ttccttgtca
    89821 gctagccaaa aaataattgt tttatcgcca actaatgctt ggtcatggga ttcacaatat
    89881 cctatatttt tttctccagg tcgtctagta gtaagttcat accacatttt tcccaaatcc
    89941 cagtcttcat cagataagtt agagatagtt tttatccaaa aatcaggtac tcccattgca
    90001 agtctatagt caaatccaat tccgccgtct tttataggga tacacatacc aggcattcca
    90061 ctcatatctt ctgcaatact tatcgaatta ggtttaattt cttttattaa ttcatttgca
    90121 aattggagat atgttatagc ttcaatatct gtattcatac taaaatattt ttcataacta
    90181 tcaaatgaaa ctccaagacc atggttatga tataacattg aagttacacc atcaaaccta
    90241 aagccatcaa aatggtactc atttaaccaa aattttatat ttgaaagcaa aaaatgtatt
    90301 acttcaggtt taccatagtt aaaaagtttt gtaccccaag caggatgatt tccctttgaa
    90361 cctgagtgga aaaattgatg ttcacttcca tcaaactcat ttattccttc taaagtattc
    90421 tttacagcat gagaatgaac taaatctaat aaaacagcaa tccccattga atgagcagtg
    90481 tttatgaggt tttttaagtc ttcaggagta ccaaacctag atgagattgc ataaaagttt
    90541 gaaacttggt atccaaaaga tgcataatat ggatgttcca taatagccat aagctgaatg
    90601 gtattgtatc cagctttttt tatcttagga agtatttttt cagtaaattc attataagtt
    90661 ccaatagatt cgctttcagt agacatacct atatgacatt catagattag tggagaagtt
    90721 atgtttttta agtcaaaatt attgtcagtc cagataaatg gagtttttgg ttgccatatt
    90781 tgtccattaa atccaccaaa atctttttga attactcttt ttatatataa tggtatacgg
    90841 tcaaatgttt ttccatttgc agtaacttgt acctttacct ctgatttgtg aggtaagcta
    90901 ttttgaccag gaataaatat ttcccaatta ccagacccaa tttttcttag aggatgagat
    90961 tttctattcc aattattaaa gtcaccaatt agtgacaaac tatctgcatt tggagcccat
    91021 tccctataga agaatccatc atttgtctga tgaaatccat agtaaagatg agcatttgca
    91081 aaagaactaa aatctttata gtttttcaat gtttttgatt tcatatcctc ataatgtttc
    91141 attcgctttt ttatatcaga ttcaaatggt tgtaggtata catcaatatc taaaatttta
    91201 aatctttttt gacttttcat tgtatttctc ctccataata aatattacat ctaaaaaata
    91261 atatttatct catactatct tctctgtata attgatatat attatataat cctaataaaa
    91321 agcttaagcc accaatgatt aatttcataa tttacctccc tagtatttat acttatatat
    91381 cgtattcatc aaaatttaaa agtttgttta aaactctttt aataatatca taatcaaagc
    91441 ctttatagga aagatgttga gaaatttttt gatatatttt ctttttatct tctttcttta
    91501 ctctttcata cctttttttt gctagataca tagcattttc aaattcagtg tccttgtcta
    91561 attcagatac tgcttcattg attgtacttc tattgatacc tttattatat aaattctgct
    91621 taattctgtt tttgccacat ttatttaggt taacatttgt gttaacaatt ttttgagcta
    91681 atacactgtc atttacgaga ttataacttt taagaaaatc tatgaccctc tcaattatat
    91741 tttcatcaaa ttctgatgat agtttttctt ttaatttttt ttcagattgg tcagcatgag
    91801 ataaaatatt taatgcttta tttttagctt ttatatacat ttcatcatct aaaataggtt
    91861 ttaattcttc ttcatttatt tcattcccct tttttaaatt aaatgtataa acaagttctt
    91921 taaatatagc aataaaaaat ttatcatcta cataaatatt aactctatca tcatttcttt
    91981 tttgttgttc tatttttgta attataccca taagtcctcc ttttttatat gtaattatat
    92041 taacaaaagc aactaataaa atttaacaaa aaacttatat ttgtatgtta tattttatca
    92101 aaattaagac aaaatagtaa aaagttattt ttattaaaaa gtaaagtaga atcatgttaa
    92161 ataattattt ttttaagtgt tttttagcat ataaatataa ttatataccc aaaaaaacaa
    92221 attataagct ttaagaaata aaaaataatg gtacaatagt attataacat taaaaggaga
    92281 caaaatatga gaagtgaaaa tctagttaag atggcagagt tgaaaaatac tgaaaaacta
    92341 gagaaattta atcgccataa aggcaaaatc aaaataggta tattgggagg tacttttgac
    92401 cctatacact atgctcattt agcaacagca gaatttatta gagataagta tgacattgac
    92461 aaaataatct ttataccatc aggaaatcca ccacataaat tatgtatcac tacagataag
    92521 tatgatagat ataatatgac acttctagca actgaaagca acgaagattt tttagtttca
    92581 aaagtagaaa tcgaaagaaa gaaaaggact tatacaatag atacattaaa atacttaaag
    92641 aaaaaataca aaaatgcaga catttatttt ataacaggtg cagatgcaat ttgtagtgtt
    92701 gaagagtgga aagatgtaaa gaaaaacttt gagttagcta cttttatagc cgcaactaga
    92761 ccaggaatta gtttgttaag gtcacaagag actatagaaa aactaactaa gaagtataat
    92821 gctgacatta taacagttta tgttccatca ctggatatat cgtccacata tataagggaa
    92881 cagctaaatg aaggcaagtc aatacgttac ttagtacccg aaaatgtaga aaattattta
    92941 tatgaaaata aactatatca atatggagat gattaaatga acttagaaaa tattaaccaa
    93001 agactaaatc aaatgctacc agtggggagg cttagccatt caaaaaatgt tgcaaaatgt
    93061 gctgaaaaat tatgtgagat ttatggatgt gacaaagaaa aagcttactt agcaggaatg
    93121 attcatgatt gtgcaaagta tttaagtgac aaggaaatag aggattatgt aaataagtat
    93181 gaaatatatt tagacccaat agaggatgga aatcgttcct tgtctcatag tgtaattggg
    93241 gcgtacatat gcgagtatga atttgaagta gaagatgaag atattataaa tgcaatcaaa
    93301 tatcatacaa cagggagaga ggacatgtct cttttagaaa aaataattta catagctgat
    93361 ttaattgaag aaggaagaaa attcccagtt gtagatacat taagagaatt agcatatgga
    93421 gggaagcttg atgaagcact tttaacttct tttaataata ctttaatgtt tgtcatcaat
    93481 aaaaaagaag agatacatcc aagaacagtt atggcaagaa actatctaat taaagaaaag
    93541 ttattataaa aaagctatat aaaggcaaac atattaataa atttaaattt gactatgtta
    93601 caaaatcgta ttaatatgtt acaataacta agtgtatttt aattaggaaa gtgaggaatt
    93661 tttatatgac agtggaacaa atgacaaaaa tagcatatga tgccatagaa gataaactgg
    93721 gtcaagatac agttataata aatataggaa aagtttctag tttgtgtgat tattttatta
    93781 ttactacagc atcttctcag agacaggtaa aagctattgc tgacaatgtg gaagatgaat
    93841 tagcaaaact aggattagag ccaagaggta aagaaggaca aggaactcaa acttgggtac
    93901 tccttgatta tggagacata atggttcatg tatttaatga ggaaaataga gggttttata
    93961 atttagaaaa attatggaaa gatgcacctt atatagatat tgacacatta gcataaacat
    94021 gataatatat gttattataa ttagaaaatt tcaaaaatta tattaaattg aatagactag
    94081 agcagtaaaa gattatattt tttcagagag ttagtggaag gtgagaacta atattatata
    94141 actttgaact tactagatta aaatctattc tccatggctg gattaaaagc tatctaagag
    94201 agtctatata tgtagtaggc taattagggt ggtaccgcga agatttatcc tcgtccctaa
    94261 acgtaagttt agtgacgagg attttttatt ttcaaagaat tatttggaaa ttataagtaa
    94321 ataatactaa ataaggtagt tatacacaat taaaaatagg aggcaaaata tgagcgtata
    94381 taattttaaa gaagtagaat cgaaatggca aaaaatctgg aaagataata atcagtataa
    94441 aatggatact gcacaaactg aaaaacctaa ttattacaca ttagaaatgt tcccttatcc
    94501 atctggaaaa atacacatgg gacatgttag aaattattct ataggtgatg ttgtcgcaag
    94561 attcaaaaaa atggaaggat ataatgtact tcatccaatg ggatgggatt cttttggatt
    94621 accagctgaa aatgcagcta taaaacatgg aatacatccg cataaatgga caatggaaaa
    94681 tatagaagaa atgaaagagc aattaaattt attagggatt agttatgatt gggataaaga
    94741 agttgcaact tcaactccag aatactatag atttacacaa gaaatatttt tgaagttttt
    94801 agagcatggg cttgcatata agaaaaaatc atatgttaac tggtgtcctt cttgtgagac
    94861 tgttcttgca aatgagcaag ttgttcaagg agcatgtgag agatgtaaag caacagtatt
    94921 aaagaaagat ttagaacaat ggtattttaa gactactgaa tttgcagaag aattacttaa
    94981 tgacttagat acattagatg gatggccaga aaaagttaaa acaatgcaaa aaaattggat
    95041 aggtaaaagt acaggagcag atttagtttt tgatatagat ggaactgata aatctatgac
    95101 agtatttaca actagaccag acacaactta tggagttact tatatggtac ttgctccaga
    95161 gcatgaatta gttaaagaat tggttgcagg gactgaatat gaagcagatg ttgaaacttt
    95221 tgttcaaaaa atgcatacta tgacagaaat agaaagaaca gcagctgatg tagaaaaaga
    95281 aggaatgttt ataggtagat atgttataaa tcctttaaat ggcaagaaag ttcctctatg
    95341 gatagctaac tatgtattag ttgagtatgg aacgggtgct ataatggcag ttccagcaca
    95401 tgatgaaaga gatagagatt ttgctgaaaa atataattta gacataattg atgtaataac
    95461 agaagataac aaaatgataa attcagaaga atttaatgga ttagatgctt cagaaggatt
    95521 tgaaggaata atcgataagt tagaaaaaga aggtagagga aagagaacaa ttaattatag
    95581 acttagagac tggttagttt caagacaaag atactggggt tgtcctatac ctgtggttta
    95641 ttgtgatgaa tgtggaatag ttccagttaa aaaggaagat ttaccagttc ttttaccaac
    95701 agatgttgaa tttactggaa aaggggaatc tccacttacg acttcaaagc aatttatgtc
    95761 aacaacttgt cctcactgtg gaaaaccagc tagaagggaa gttgatacta tggatacatt
    95821 cgttgattct tcttggtatt tcttaagata tgtggatagc aataatgaaa atgaaccatt
    95881 tagtaaggaa ttagttaata gatggcatcc agtagaccaa tatataggtg gagtagaaca
    95941 tgctataatg catttacttt atgcaagatg gtttgtaaag gcatttaaga gtatgggaat
    96001 ggtagacttc aatgagccat ttaaaaactt acttactcaa ggaatggtac ttatggatgg
    96061 ttctaaaatg agtaagtcta aagggaatac agtatctcct atggatataa tagatgagta
    96121 tggagcagat actgcaagac ttttcgtatt atttgcagca ccaccagaaa gagatttgga
    96181 ctggtcagag caaggtgttg atggatgctt tagattctta aatagggttt atagattggt
    96241 tgacgagtta gcagatgtgg ttaaaaagga tgtagagttt ggagaattaa attcccaaga
    96301 taaggatatg agatatacta tacactctac acttaaaaaa gttactgctg atttaagtga
    96361 aaaattcgga tttaatactg ctatatcagc tcttatggaa ttaataaatg atatgtataa
    96421 atataaagag ttagataata taaacgaagc agttataaaa gaaggtgtac aaactatagt
    96481 aactataatt gcaccatttg cccctcattt aggtgaagaa ctatggacta tgataggtaa
    96541 agaaggaagt gtatttgata tagactggcc taaatatgac gaaaaagctt tagtaaaaga
    96601 tgaaatagaa gttgttgtac aagttaatgg aaaagttaga ggaaaattaa ctgttaactc
    96661 aaatatatct aaagatgaga tggaaaaggt agctttagaa gatgaaaaaa taaaaggatt
    96721 agttgaaggt aaaactatag ttaaagttgt agctgtacct aaaaaattag taaatatagt
    96781 tgttaaataa ctcaaaaata tgaacaaaaa tataaattta taaaataaat gaggctgtct
    96841 caaaatagag ataagccttt tttcattgtt gaaattataa aaatagattt gattttatac
    96901 aaaaaaatga ttaaagaact aaaaagttca ttcttatata ccctagttgt tgttttaaat
    96961 attattataa ttaatgttaa atcgagttaa tgtattaagt ggtatgtaaa tcattcagtt
    97021 tccaaagtgt tgttcatcaa ggaactgctc taagcttaaa cgaaaaaaat ataattattg
    97081 tattttgaaa tttttttcta tataatgaaa acaggcaaaa aaggtgcata tctatgcttt
    97141 atatgaaaca cccagacaac gaaattcaga ttcatataat agctaccatg tttctaaaaa
    97201 ggaacttgta aaaaagatag cgtttcaact tcccagttga ttaaaattat cagcaggaaa
    97261 acaagtatgg tcagcagtgg tattctaatg ggtgttgtcg atatatccaa gttgggattg
    97321 tctgaggatg ttatcaaata acttgtgata ggtgcagtag atgtggagat tcctgatacg
    97381 gatttattct caggggatgg ttgcttcggg agatatggag cgtaaccagt ttattgatat
    97441 ggtaaccatt ttttgtctaa tttgatgaaa gaatcccaag aataccatac agaagtaaga
    97501 caggaattaa ctggtggtat aaactgataa aggcaaattt aaaaattttg ataggatgat
    97561 tttaagattt atcttctatt ttgtttttta gaaataattg aaatgttatg aggaggtatg
    97621 tacaaatgga gactgtaaca aataatcaat caggtgtaga aattcaactc agtctgtttg
    97681 aagctatcaa agatttattg ttaattaatc ctattttctt gttgggaatt atcttgattg
    97741 gtattttctt agttgtaata ttcaagaaaa atagtgatat tccaaaggta aaaacatcta
    97801 ttttatcact ggcaatgtat tactacttat gtttaacact atcacatatt gttggtatac
    97861 ctacattcgg tgaatatata agactgtcac agttagggga aacgttcttt aatccaaaca
    97921 taaatcttat tccttttagt gatggattta gtttgagttt tattttgaat attttacttt
    97981 ttgtcccatt aggtttttta tgtccgctta taagcaaaac ctttgaacgt ttgagaaata
    98041 cattcttgat tggttttgga ttatctcttt ttatcgaaac tattcagctt tttacgttac
    98101 acagagcaac cgatatagac gacttactca cgaacgtaat tggaacaata ataggctatt
    98161 tttgcttcaa actgattgct aaattgcgaa ttgtaaaact acattcagat gatgactcta
    98221 tggaacagga ttacacagta tgtattccga ttgccattat aatagttgcc cttatattag
    98281 gattttttag ttaagttcca aatagctaat ttgggaatta tggaggtcat taagtgaata
    98341 aaattacttt tatatgttta ggtgtaaaaa gtatggagaa gtcaattaaa ttttatagag
    98401 atggattagg attttagatt acaaactttt agtttaccaa ggagatagca aagtcgtgtg
    98461 ccaaagggta accatttgga aatccagaca acataacaga tagtatgtta ccttttacag
    98521 gagcatacta tctgttatat tgtcaacatc ctattttatg gtttgtgtgt agtttcctgt
    98581 aaactgaact aaataattaa atagaagcta ttagaattaa taataacaga tagatattaa
    98641 taagcataaa caaatagtaa aatgtgtaga tatagacgtt tttaagtgaa actattataa
    98701 aataattgac tgataatcaa ctgacaaaac ctattttttt aggtttaact gacatttaac
    98761 tgacagtcag tttttactat ttaaatagaa gttcgcttag attgtcggaa gcttctttgt
    98821 ccatttcttt aagtacatga gaatatctat tcatagttat ttttatatct gtatgaccca
    98881 atctttcaga aacaactttc atattagttc cccctaaaag caacagagtg gcacttgtat
    98941 atcttaaatc atgtattcta atctttttta aattattttt tttgtaaaat tgtgaaacgt
    99001 ttttcttagt gaagaaggta gaaacggatt taaattggtg tttagacaaa ctaagttatt
    99061 tctgttttcc aggatacctt acaattttaa tttgctttgt cttagttttt caattttcaa
    99121 tttttcaatt aattcttttg gagctgataa agctcttttt gattttggtg tttttggctc
    99181 tttaaaagat attttgccat tagaatagac aagaatttga ttaacattta tcagattgtt
    99241 atctaagtca acatctgacc acctaagccc agtagcttct cacattctta aacctagaag
    99301 taacattaaa agaataggta tttctatatt attaccaagt aacttttcta ttagcaataa
    99361 tacttcttct ctattgtata tttcatttgt agaatatttt tctttagaag gaagttttat
    99421 aaaatcacat gaattttctt gtatttctct taatctatac gcttccctta ttacagaact
    99481 tagaaagcta taccttactt tagcactagt aaaggtagaa ttattaaagt tataatttac
    99541 aaaagcttgt actgaactag gatttacttc tgtgagtttt agattcttaa aaaaggttct
    99601 atgtaatttt taacccaaga ttttgtattt gtaacagtat atggagacca attattttta
    99661 ttcatgtcta tatatttata acatctttct acaaatgtca taccttttgg agcaacaaac
    99721 ttattattat ttatagtaga ctttatttca attaaatgtt tttcagcatc ctttttcttt
    99781 ttatagcttc cataactttt ttgtttcttt ttgccagttt cttattccac atatacatag
    99841 aatttttccc atctttttct tataaaagct gatttgatat tcatatatgt acgctccctt
    99901 tataagttag ttttataaaa gaacagttgg actgctctaa ttatgtcatt atctttttaa
    99961 ttctttacag ttacattata acacgtattt gtatacactt aaattaacag gaagataaat
   100021 atcattaaag gaggaaaaga aaatttaatg tagaattatg taagatatat agtatttcat
   100081 atataaaagg gggagatatt gtgaaattaa agaaattatt atcactaggg ttagccgtgt
   100141 caatgtttgc tgctggtcct atatcagcta atgcacttga tacaatttat actattcaag
   100201 gaaaagataa atatgaaacg gctgctctta tagctgatga acaaaattat actacagcta
   100261 tattaattaa tgcagacagc acaatggctg atggattaag tgcgagtgga cttgcaggag
   100321 caacaaatgc accaattttt ttaactaaga aaaataacat acctaatgca actcttaaaa
   100381 gagtagagaa agctaaaaag gtatacataa taggtggaga aagttctatt gataaagcaa
   100441 cagaaactct tctaaaagat aaaggaatag aggctaaaag acttcaaggt agtgatagaa
   100501 ttaagacaag ctataatgtt gcaaaagaaa taaactcaat taacaaagta aataaagtta
   100561 tattgactaa tgcttttaaa ggagagcctg atgcaatgag tgctgcacct gtagcagtta
   100621 gagataaagc agctatagta ttaactgatg gaaaaagtgt tccatttaat acaactggtg
   100681 tagaaagtta tgtaataggt ggtacttcat caatgagtga caaactagtt aatgatacta
   100741 attcaactag attaggtgga gtagatagat atgatactaa taaaaaaata gtaaataagt
   100801 tctataatgg cgcaaaagaa ttttatatag ctagtggtac tgatttagtt tatgctttag
   100861 ttgcttcacc aatggctaaa aataatccta ttgtactagt tgatattgga agtaataaag
   100921 atatacttaa aaatgctgca aaagtgactg ggataggaaa tctaagtgat aaaattatgc
   100981 tagagtgtga aaataccatc aataatatta gtcttccgtc ttcaaataaa aatataatat
   101041 gtggattaaa gattgatttt gattcaaagc acataatttg gcaagataaa ggaagttatc
   101101 ttgaatgtta tgatgataac cttgaatatt atactgaaaa atataaagac ccaacagttc
   101161 ctataaatat agaaaataca agtacacaaa atttagatgt aacaaaatta aaagtttatg
   101221 gagaagctaa ttcaacatta tatatggggc aatatgctaa aataaaaatg gattttaata
   101281 gtttcggtgt attaaagcca ggagaaaaat gtactattta tttagatata atttcattag
   101341 atccatcaag aagcatgaca ttaacatttt cttatgtagg tgataaagaa aattataaat
   101401 atgaacaagg attggcaagt agaatattat tttataaccc agatggagaa gatttttttg
   101461 aatataaata actagtgggt atgtaaatta ataagggttt tataagttta atttttttat
   101521 tttcgtttta tattaactat gtggtatgta aatgtctcga tattgctcat atgttgagtt
   101581 attatattta gtttcatatg aactatatgg attttaaaat taaaaatact taaaaacatt
   101641 tactttaata gtaggtgttt ttttgattaa aagaatatta ttataatgta aaaagtaata
   101701 aataggtaaa atatgtaaga attatatgtt ataatatttt tagcaagaag atgtaatcta
   101761 caatttatag agtggagttc atgtatcaaa aaattatcct cccgacgcta agaagggagg
   101821 tgaatataca tggataattt tttacaaggc atactagcaa gtctatctgc tagcttaata
   101881 gtttatatag ctagcaaact atttagaaag cgtaaaaaac cactcaaagc ggcaactaag
   101941 agtggttggg aatttgattt aaaaatcaga ttccataaaa ctaagtaatt tctaaattat
   102001 gaactccact ctacagcaaa atagattgta gttcttcttg cttttattat atcacaaatt
   102061 ggtacagata ttcaaaaata atatttttat gatataataa agtcatagaa attttgcagt
   102121 gttcgatttt ttgaagaaat taaggcttaa cagttgaaat ataaggcatt gaggacttgt
   102181 gataagtgtt atcaattgca ctactcatgg ttcactgcaa atttgagaga tttgtatatg
   102241 tgtaggcatt ggaaatactc aatttatttt ggggttttat attaactata tggaatgtaa
   102301 atttacctat aaaactagca aaatattctc taaagtcctc gttttatatt aactatatgg
   102361 aatgtaaata gtatttcagc aattttactt ttaataactt tatcagcgtt ttatattaac
   102421 tatatggaat gtaaattcaa tttaccgttt ttttcaaatc tcacaacatc agagttttat
   102481 attaactata tggaatgtaa atctatcggc ttcttgaaaa gcctcatctg ctctatttag
   102541 ttttacatta actatatgga atgtaaattt cattaaatcc ccaaccgaat tatctttcag
   102601 catttgtttt atattaacta tatggaatgt aaatcatgct gataagaatc tctatgaact
   102661 tcggagggaa ccggttttat attaactata tggaatgtaa atttgggtat tttgctaaaa
   102721 ataaagctat taaattagag ctttatatta actatatgga atgtaaatcg tattaacacc
   102781 tgttcggcac tatcacaata aacacaagtt ttatattaac tatatggaat gtaaattgta
   102841 tccaaaaaat tacaataatc atacgaactg ctaatataag cagtcaatat atgtgtacat
   102901 ttatccattt tatctctaaa catataaatt attatccccc taaaaaactt tcataaaaac
   102961 aaaaagaaca atatctcttt ggcaactggc taacataact cataagatat ttatataagt
   103021 cttagtccct atagctttgc gtcactagat ttctctagtt ttgccgattt agttttattc
   103081 tataactaaa taatacaata gaattagtta ttattcaaca agattgtttg aaaattgaat
   103141 aaatttatag gtatgaacgt aatttcacac ttaaaaacag actaaatacg tagaatatat
   103201 agaaaaattt acctgtagtt tttgtgataa aaagctccta ttattaattt aagctagata
   103261 agtttgagga agtgacataa attgaaagaa ggaatatatt atgttgaata aaaaattacc
   103321 agatgcagaa ttaaaaatta tgaaatacat atggaatact ggttataaaa ctgtaatatc
   103381 aaaagatgtt gcagattaaa tagaaaaaac atatgcttgg aagcatacaa ctacaattac
   103441 acttttagct agattaacta aaaaaggttt tttcatatcg cagagaattg ggaaacatgt
   103501 acactataga gtattaataa aagagaaaga atatctcaaa atagagggaa aaagaatttt
   103561 tggaggtcta cataacaatc cattatcaga actaatttca aaattacatg atggagaaga
   103621 aataactgaa gaaaaaataa tagaaatagg aaattggata aaaagctgga aagatgaaga
   103681 ttaataaata aaaggtagct actaatataa gtgctacctt ttttcttgtg gataatattg
   103741 gggataagtt gtggaaaatt tgtgtaaaaa ttgtggataa aatattttgc tgacatttaa
   103801 ctgacataag tattagattt tgatttaaaa atgttgaaat atcaataaat aattaaatag
   103861 aagttattag aattaacaat agattccttt ttcaaagaaa tctttgattt catcaaggtt
   103921 atcagttttt ccaagtgcta agataagttt tattctagct ttttgacctg gtaagtcccc
   103981 accaaatata caaccaagat tttttaaatc tctaccagaa ccaaagtaac cataactatc
   104041 gaatactcta cctgaatgac atctagaaac tataactaca ggaagtcctt tttctctagc
   104101 atattcaact ccagaaagca tttgaggagg aatattacct ctgcccattg cctcaataac
   104161 tataccttta taaccactat caacagcaaa tcttataaag tcagcatttt ctcctacata
   104221 tgctttaaat aaggcaactt tagattctac cttatcagta tctataattg ttctatttac
   104281 aatatctctt gtaaggacaa gttcgttgca gtcaattatt cccaatgggc cactagttag
   104341 agatttaaat gtatttagag aaagagtatt tgttttagta gcttcagaag ctaataatac
   104401 ttcattgttt aaaactacaa ggactccttt tcccatagca tctttggata ctgcagtaca
   104461 aactgatgca gataaattac ttgaaccatc atatccaagt tcagaactac ttctcatagc
   104521 acctgtgact attacaggtt tgatgttgtc aattgtaagg tctagaaaat aagctgtttc
   104581 ctctaaacta tctgtaccat gtgttattac aacacctgta atatcttttc ttgctaataa
   104641 atcatttaca tagtttttca attccatcat tctataaggt gttatgtgag gtcctggaat
   104701 ttcatcaaaa ttaaaaactt caacatctgc aactttatca atgttggtaa ccattgatag
   104761 tatttgttca cctgataaag ttggtatagc tgctccgact ttatcatcta ctgtcataga
   104821 tatagttcca ccagtaaaaa ctatggcaac ttttttctta atactcatac tattctctgc
   104881 ctttcataaa taaaatttat aattccgata ggattatatc aaaaaaagta gttaaggtct
   104941 acataaactc ttttattcat ataatttaga tatttcagtg taatataatt atttcttaat
   105001 tttttgccat tcaacgatat aaccatttaa tatctctctt atggcttttc ctatcttagt
   105061 ataagcttca tcatatagat ttgctagaga tattctaatt gaccattcag gaccatagaa
   105121 tccatttcca ctaagtaaaa ctactgaata gtcattagct aatttataaa gaacatctac
   105181 tggagatgca tttttactta taaatttaaa taagccttct ccgtagttta atttagccca
   105241 ttcttcaata tcaaattgag tgtaatatgc agcattgttt ttgttttcat taattggaag
   105301 ctctaaagct tcaaataata gtttttgacg tctatggcag atactcatat tgagtttttt
   105361 gtaggcatct actttgtcaa tcaatgcaaa agcagagaaa aacgccattt gtacttgctg
   105421 tggagtagaa agaccagcag tatggttgag agcaacaagt ctgctatcag caacaactct
   105481 ttccataaat gaaaggctag aagggttaag actcatatca ctgtaacgct tatctactga
   105541 tttttttaat tctccagtta aatcatttat tttcttatca aaaacatttt tcttatgaag
   105601 ggcaaatgta ccaagtctcc atcctgtaac tccaaaatat tttgaataag aatatactcc
   105661 aacagtgttg taaggtagtt ttgacattaa ggatgaaaaa tcttctacaa aagttccata
   105721 tacatcatct gatattatca ttaaatcttt attataattt tcaattacat ctattagatt
   105781 attacaagat gtttcatcca tagctataga agcaggatta ttaggattaa caacgaataa
   105841 agctttaata gatttgtcac gaagtttctc taattctttt tttgtatatt gccatgtgtg
   105901 agcacctttt tcatcaactt cattagcatt tatatttacc actttaaagt cgtaacgagg
   105961 aaggttaggt atttcaagat aaggtgtaaa tattggagtc attaaggcta ttgtatctcc
   106021 tttttttaga agttcatttg ccattaatga atcaaatata tagcacatag cagctgtagc
   106081 accttcaaca gcaaaaattt ctacatcacc atatttacct gatatatcat atttcatttc
   106141 ttgaactagg taatcgtgta ctattttttc catatgaggt aacattctat ctggaagtgg
   106201 atagttatca ccaataattc catcagctag ttcatgaaca aattcatctc catcaaatcc
   106261 aagttcattt ataccaaagt ttataatatc tctagctaaa tatgctccag gcatatctat
   106321 attttcattt ataaatttaa aaaatctttc tttaataccc tttttttgag gcattccagc
   106381 caaatgacct aaatcccaat tagaacgagt ttcagtaata gcgaaatgac caaaagtaaa
   106441 aaaggcttct ctagcagttg aacaagtcca gtttggattt ccacgacctg catcaagtaa
   106501 ttctctgtta ttttcttttg cagtgtattt tgcaatatct attaatttgt ccttaaattc
   106561 aaaagggctt atttttccat atatgttttt gatttcttta taagtatgat ttttcatgtt
   106621 aaattcctcc ttatgtaata agtttcacat ttttataata aaataaacaa gttgcaaaaa
   106681 tgattatact ttaattataa taggtttata gaaaaagtaa agtatgaaat taaaataata
   106741 actctattta gccttattaa atatatgtta aaataaaaaa taccttttaa taaaaaatga
   106801 ttgttatata aaataaatat tcaatttaat tatcacctta gtttttttat tgtattttat
   106861 tatatatgta tagttttcta attttgaata aaaataaagt aaaactttct tttatattga
   106921 agttgtttag taagacatgt attttattaa tttattaatc ttaataatgt taaataaaat
   106981 caaaaaaata gattttgggt aaataaaata atataaaata taaattttaa taaaaataat
   107041 aaagtatata ttattgcttt aataagaatg taaaaaatat ttttaaatta tcatttaatg
   107101 taatttaaat gaattgaaga tatatgttta ttgtatgcaa ttgttgtatt tttaggtttt
   107161 ttgtgattaa ttaaaaaatt ataaaaatcg tttacatgtt gatttttaaa aaaaaaagat
   107221 atagaattat atagaaagta ataaacaaaa attggattta cgggagtgga atgaaatgat
   107281 gaatgttacc ttaacagatg taaaagaggc tagagagacc attaagaaca tagtaaaaag
   107341 aactgactta cttgaaagtg ttaaacttag cgaaaaaaca ggagcaaatg tgttctataa
   107401 atgtgagaat cttcaaaaaa caggttcttt taaattaaga ggagcttgta acaaaatagc
   107461 gagtttaaca gatgaagaaa aggcaaatgg agttatagct tcaagtgcag ggaatcatgc
   107521 tcaaggagtt gcattgggag caaaaatgac tggtataaaa tctacaatag taatgccagc
   107581 aactgcgcct ttagcaaaag ttagtgcaac taaaggttat ggagcagaag tagttttaaa
   107641 tggtgcggtt tatgatgatg catatgcaaa agctgttgaa atacaaaaag aaacaggagc
   107701 aactttctta catccattca atgataagta tgttatagca ggacaaggaa ctatatctct
   107761 tgaaattttc gaacaattag acaataaagt tgatactata ctatgcccag ttggtggagg
   107821 aggaatcatc tctggtgttg ctgttgcagc aaaagcatta aatcctaatg taaaaatagt
   107881 cggtgttcaa actgcaaata taccttcaat gaaagagtca ataaaaaatg gaaaagtaac
   107941 aacagcattt aatgatacta caatagctga tggtatagct gttaaaactc caggagattt
   108001 aacttttgaa ataataaatg aattggttga tgaaatagta gtggttgaag agacagaaat
   108061 tgcagaatca atattattta tgatggaaag tcaaaaaata gtttcagaag gtgctggtgc
   108121 tgtatgtaca gctgctatat taagtggtaa gtatgtacca gcaaaagatg aaaatgtagt
   108181 ttgtataata tctggtggta atatagacat aaatacgtta tatagaataa taggtgttgc
   108241 tttagctaaa gaaggaagaa gatattcatt tagtacaatt atggaagata agccaggaaa
   108301 ctttgctgag ttaactagaa taataagtga gaatggtgga aacattttaa gtgctaatca
   108361 aggtaaatta tcagcagggg aagctctagg aaaacaaagt gcggaattta tattagagac
   108421 aatagattat gaccatatag ctagaataaa gaaagctata gaagaaaaag gttttaaaat
   108481 tatagaatta taataaaaag tgtatataat atacaagaaa aatagtataa tagtgtatga
   108541 agatacattt tatgtgtatt agattaacga attaggagga ttttaaaatg aaacatgaag
   108601 taatacatac taatgatgca ccagcagctt taggaccata ttctcaagct ataaaagctg
   108661 gaaacttgtt atttgtatct ggacaagttc ctcttgtacc agagactatg gaagtagttg
   108721 aaggagatgt acaagctcaa actgctcaat ctttaaaaaa tcttaaagct atattagctg
   108781 aaagtggagc tgatttttca aatgtagtta agactacagt atttataaaa gatatgaatg
   108841 aatttggggc tataaacgaa gtttatgctg aatattttgg agaaaataaa ccagcaagag
   108901 cttgtgtaga agttgctaga ttaccaaaag acgttaaagt tgaaatagaa gtaatagctg
   108961 tattataaaa atacaatatt tttaatttga aaaggctgaa aaactatatt ctagtgattc
   109021 agccttttta taaaaaaata aatcacaata aagaacatga taaatattgt cgaattaaaa
   109081 aataaaatta aaataaatat tgcaatattt ttgagaaggt tttataatga gtatataatt
   109141 tgaaacgtgt aactattaaa ttaggcatga gttcttggat atttttatcc tgaggattca
   109201 tgcctttttt gtattgaaat tcaaaaatct atttaataag gaggaagtac tgtgttaaat
   109261 tttttcaaga aaaataaaag ctataagtta catgcagtag tgagtggtaa cagcattaat
   109321 attgagaaag taaacgattc tgtgttttca aaaaagttaa tgggagatgg agttgcaatt
   109381 attcctaata gtgatgttgt tgtagcccct tgtaatggta aagtaactgt gcttacagaa
   109441 tcaaagcatg cctttggtat ggtctcagat gagggtgttg aaatattagt ccacatagga
   109501 attgatacag ttagtttaca gggtgagggg tttaaaaatg aagtgtctca aggagatact
   109561 gttaaaaaag gtagtccaat aataagtttt gaaagagaaa aaataaattc tcagggaatt
   109621 gattgtacaa caataataat tgtattaaat catagcgaat tttcagaaat aaattgcatg
   109681 gtagaaaatg aagttgttgc agggcaagat actgttattg aaattatgaa ataataggaa
   109741 gggattaatt caatatgaga gtagtaaaaa tctttaataa taatgcatta tctacagtaa
   109801 ctaatgatag gaaagaagct attttactag gtcttggtat aggttttaat aaacgtccag
   109861 gagataaagt taatgaagat aaaatagaaa agatttatta tgttcaagac cacatgcaaa
   109921 caaaattttt agaattatta aaaaatgtta gtccagaagt gatggatgct tcacaacaaa
   109981 ttataagtct tataccagga aatgagggaa aatttaataa taaagggata ttatctttag
   110041 tggaacatat tagttttgca atagatagaa tgaaaaataa tgttttttta cctaatttaa
   110101 tgcttttgga tataaagatg atgtattcaa aagagtttga attaggagta aaagctttag
   110161 aaattatata tagagtatgt catatccatt tgcctgaaga tgaagcaggt tacatagctt
   110221 tacattttgt caatttacaa tcaaatgata atttggcata tgatacttta aaatttgtaa
   110281 aaggtagtat tgatttgatt aaagaatgtt atggattaga attagacgaa tcgagtttaa
   110341 gtacattacg ttttagaact catcttaaat ttcttgctca aagaattttt aagaatgaaa
   110401 tttgtcagga tgataaaatg attgaaatgt atgattattt aattaacaat catcctaaaa
   110461 ataaagaata tttagaaaag ttaaatgtat atattgaaaa ggagtttagg tataaattag
   110521 ataaacctga aaaaatttat ctactactac acctaacaaa aatcttataa gaatgagatg
   110581 aattagtaat agaaatatat ataattttag ggggggataa gattgaaaga aaaactactt
   110641 ggaggactgg aaacatttgc aaaggcaatg gttcagccat taatgtattt atcgagtgca
   110701 ggaatattaa tggtggtagg tgtactactt acaaatgata tgttattagg agtacttcca
   110761 ttttttaaat gggagccaat tcaaatattt ggaagcctaa tttataactg tataatggct
   110821 attattaata atcttgctgt tatatttgct ataggtattc ctgctgcact agcaaaaaaa
   110881 gagaagcaca aagcagcgtt aataggattt atgagttata taatatacct tacagcttcc
   110941 aacactatgt taacatcact aggtcaacta gcaaaagaaa gcaagatgct tggactgata
   111001 gggactggac aagctactat tttaggtatt caagttgtag atacaagtgt atttggtgga
   111061 attattttag ggtgtatagc tggatatgta tttaatcgta caagcaacaa aacatttaaa
   111121 ggagctttac agatatactc gggagcaaat tttagtttta tatgcatgtt ctttgtatcc
   111181 attttaattg gagttgtgag taactttata tggccattag ctcaacaagg aatagcttct
   111241 cttgcaaatg tcatcaaaga tacaggtaca tttggtttat tcttatatgg ttttttagag
   111301 agaatattag taccaactgg acttcatcat ttaatttata caccatttca gttttctgat
   111361 ttaggaggag tgcttaaagt tggtgcagat acagtttcag gagcctatgc tatagttatg
   111421 acagaaatga atttaccagt tgagcgtttc tcagatagta tatactatat ggcaactgga
   111481 tttacaaaga tgtttggtta tataggtata ggagctgcct ttatttatac tgcatataag
   111541 caaaataaga agaaggttaa ggcaacgatt attccactaa taattacagc agtattagcc
   111601 tctgtaacag aaccattaga ctttatgttt gtattctgtg caccactttt attctttgta
   111661 catgcagtta tagctggtct ttttatagct ttattaaaaa tatttgatgt tactgcatta
   111721 tgtggaggga acttattagt atcaattata atgaatacta cagtaggcgt agaaaaaaca
   111781 cactggccag taatgatgat attaggactt gcacaaatta ttgtatattt tgtagtattt
   111841 agttttttaa ttaagaaatt taattataaa actccaggtc gtgaagatga gagtacagct
   111901 acaggcgaag aacaatcaaa acaacttaat ttagatgcag ggatagaaaa tataattgat
   111961 gggttaggcg gaaaagaaaa tattaataca gtagaaaatt gcatcactag attacgtgtt
   112021 aatgtaaaag atgaaagtaa gattaatgaa gatataatta atttaacgcc aaatagcggg
   112081 attgtaagga aaggaaaaga tatacaaata atttttggac ttcatgtgca tgaggtaaga
   112141 cgtgcagtag aagatttttt agaagcttat taaagatata tatttatata gcaagggtaa
   112201 ataacagctt taagtgctgt ttactattta ttaaagatac atataattta tagaggagga
   112261 ataattatta tgattattac tattgttggt ggaggaagca catttactcc aggtattgtt
   112321 aagtcaattg cattaagaga aaaagagtta gagcttgagg aaattcgttt atttgatatt
   112381 gataaaaaac gtcaagataa agtagctgta gttgtcaact ggatactaaa agaagatgtt
   112441 aaaacagatg ttaaactaac tgtaactaat tgtgaaaaag aagcgtatac agatgctaca
   112501 tttatatttg cacaaatgcg tgttggtaaa tatgaaatgc gtgagcagga tgaaaaaatt
   112561 ccattgaaat atggttgtgt aggtcaagaa acttgtggtt gtggagggat ggcatacgga
   112621 ctgcgtacaa tacaaccaat gataaaggtt attgatgatg tagagaaata tgctaaaaaa
   112681 gattattgga tattaaatta ctctaatcct gctgcaatcg tttctgaagc ttgtcgtaag
   112741 ttaagaccaa atgcaaggat tataaatatc tgtgatatgc caatagctat tatagatatg
   112801 atagcggggt cattaaatat caatgacgtt cataatatac gctatgatta ttttggtcta
   112861 aatcattttg gctggtttac ttcaatagat tataaacata gagacttaat ggaagagatt
   112921 aaggaataca taaaagaaaa taaaatatta ttaccaaaat cttatataga aaacttaaat
   112981 aaaagtcgta gtacaggaaa tcgccatgct gtaagtagct ggatacatgt ttgggaatct
   113041 gtttatacaa tgttagaaag cttcccaaaa tatctgccaa acacttattt aacatactat
   113101 cttttaagta aagaaacagt ggaacattca aacataaatc gtactcgtgc aaatgaggtt
   113161 atggaaagcc gtgaaaaaga cttatttgaa ggtgtgagac attacttaga aactggagaa
   113221 atttctgaaa aagcatttta tgcaggttta catggagatt ggattagtga tttggcagtt
   113281 tcaattaaaa atgatacacg tagtcgtttt ttagttataa ctgaaaatcg tggagctata
   113341 ccaaacatgc catatgatgc aatggtagaa attccagcat atattggtaa agatggtcca
   113401 gaagttattg ctcgaggtcc aatacctcta tttcaacaag gattaatgat gcaacaactt
   113461 aacagtgaaa aattgatagt agaagcttat atagaaaata gttatgaaaa agctttacaa
   113521 gcattcacat taaataaaac tattccaagt atgaatgttg ctaaagaaat tttggatgaa
   113581 atgatagaag ttaataagga atactggcca gaattaagat agtaggataa aagaaagggt
   113641 ttttatttaa tcattagata tgttttcaga gtcttttatc aaaatgtatt cacaaacata
   113701 tggcaatata ttaaaataaa gagtgatatt tttagaagaa tggggtgatg caatgaacat
   113761 tataaataaa attttttggc aagaagatag gattggcatg attacaaata atttagaggc
   113821 agatacacat agtcactgta tgttacaact gttcttaagg atagaagaca gcattgaaat
   113881 aacagttaat gaaaaattag ttaaatgtaa ttgtatcata gtagataaaa atatctctca
   113941 ttcattttca gcaagaaaaa aagtttatta ctctgctatt attgaaccta catctatata
   114001 tgcagaacag cttacctcaa aaatgaatga ttttggctac tggatatgtg acaataatgg
   114061 attagagaaa ttacgtcaac aaggaacttt tttgatagat aactctagta aagaacaata
   114121 tttaagattt atggaaatgc ttaataacta tttgaatata cctataactc taaaacatta
   114181 tgatgacaga attactgaat tgctcaattt attacgtact tgtaattgtg ataatcatac
   114241 tatttcaagt tttgcagata aagtgtctct atcagcaagt agattatcac atctgtttaa
   114301 agaacaaata gggatacctt taaaaagcta tatcttattt catcaaatgg agtgtgcttt
   114361 tagagaatta ctttctggaa aaaatgttac cgaagcttct atgactgctg gattcgatac
   114421 tccatcacac tttgcaggga cagttaagcg aatgatggga atgcctgttt ctttatcttt
   114481 gaaagatagc gagtttttga aagtatatta aatattctcg ttatataatg aagttgtact
   114541 aagaaagggg ctttgttatg aataaagaat atttagaaga aacaaaaatg ttaaattata
   114601 atgaaccaca acttaagctt ttggtatcat caaagaattg gttggaatta gatgattttc
   114661 ataaaataaa atctatttat gagtttgtac agaatgatat tttatttgga tataatgctt
   114721 ctgatatgtt aagcgcaaca caggtattaa atgatggtat gggacaatgc aatacaaaag
   114781 ctactctttt aatggcatta ttacgtgcag tgaatatccc ctgtaggctt catgcttttg
   114841 atgtaacaaa agattttcaa cgaggagcta catccaaatt gatttcacta ttagcaccaa
   114901 aatatattct tcatacttgg gtagaggtat tttatcaaga taggtggatt gctctggagg
   114961 gtgtcataac tgataaaaaa tatttagaag caattcagaa gaaatttttt aatcatggtg
   115021 gaacgtttaa aaagtatgca atagctacaa atgatttgaa aaatacatct attgattggg
   115081 atggtaaaga tacttttatc caaaaagaag ctatcgtgta tgattatggt atttttccat
   115141 caccagacgt atttttttct actcattcac aacatatgtc aaaattaaaa aatttcatat
   115201 atgtacatct tatcagaaaa ataatgacaa aaaatgtatg taaggctaga aacaattata
   115261 ttgataaaaa tgaatgagtg tttaagaggt aactatatag gaaatatata gaataattaa
   115321 aactgtactg gttaaaatga ataaaaagga gttatcacag agcaaactta aattgttcat
   115381 aggataactc cttttctgta ttaacttcta ataatttgat gtctttttat aaaacatata
   115441 gatacaatta aaccagtaaa tgcaagagta gctgctattg aaaatgcaac atctattcca
   115501 tgaatgttag acagcatgtt tgaactcata tgagctttct tagtagcact tgtcattata
   115561 gtaataagta tagcagaacc tatagctcca gatatctgac ggagtgtgtt attaattgct
   115621 gtggcatgag atataagttc tctatctaat gttttaattc cccatgtagt taatggcatt
   115681 aaaaccattg aaataccaat catacgaata caatacatca atgacacatg aattaaagat
   115741 gtatctctgc ctaaaaaagc gaaggataaa gttcctaaaa acaaacatcc tgttcctaat
   115801 attgatagag catgaggtcc atatttatct aaatgacgtc ctgcaattgg attgagtaca
   115861 accatcaata tagcaccagg taacattaat gaacctgaag ataatgcaga aaatcctctt
   115921 acagattgaa cgtacagagg aatcattaat gtagcagaca tcattgaggc atatacaatc
   115981 ataattaata ttgtagaaat aagaaatggt ttatttttaa aaaccctcaa ttctaaaaaa
   116041 ggttctttag attttaattg acgcaatgta aataaaatta atgacataat tcctattaat
   116101 attggtaaat atgtggcaat attagtccac ccataattac cttgattagt aaatccaatt
   116161 aataaaccac caaaacctag agatgatagt actattgaag gtatatctaa ttttagtttt
   116221 tgagtttccc caacatttct taataaaata aatgatagta taacatctaa tatagcaata
   116281 ggggaaagaa acagaaataa actatgccaa ccaaatgaat ctactaacca tcctgataaa
   116341 gttggaccta ttgctggagc aaatcctact gtaataccaa ctaaactcat agctgcacca
   116401 cgtttttcct cagggcataa atagagtata ataacttgta aaagtggcat tagagaacca
   116461 gaacccattg cctgcaacac acgagcaatc aacatagttg aaaaattatt agaaaaaagt
   116521 gcaataatac atcctataga aaagatagac attgatgtaa taaataactt tctagtacta
   116581 aatcgattta ttaaataagc tgttgtgggt acaataatac ctgcaataag tagataaatt
   116641 gttgttaacc actgaccaac atcagcagta attttaaaat ctgacattat attaggtaat
   116701 gctgttgaca atagtgtttg actgagagaa cttataaaag caccagtcat tacaattgct
   116761 attattaaat ttcctttttt attgttactt tgggtttcca taatttataa cgtctccttt
   116821 tttaattgat ttttaatgct gttcaataaa agtacttttg gtcttaaagt gtcttctttt
   116881 tctaaatatg caatcattgc atccataatt aaagaatcat attgttgatt ttttccctcg
   116941 acgtataatt tttttattgc ttctagtaat ttaggatttt caaggagaga agtatccgtt
   117001 ttgattagtt cttctatatc ttgtatcgtt ttaaaaaata gcgatttatt atgaagggaa
   117061 aagtaaactt catcttcttg tttatgtaaa aacattgatt tttcaattaa aggatttaga
   117121 ttatccatat tttctacaac taaatctaga atttgtatag taaatttggc aataaagtat
   117181 acatttattt ctcttttttg tacatgaata atgtatataa actgatgaat tagagcatcc
   117241 aataagaaaa ctaaatcaaa tataattttt tctattttat caccatagtt atcaaataag
   117301 cttagtttgt attcattcaa taagttagct cttgattttg tttgcaattt acttgtagcc
   117361 ttacgttgct cttcagaaaa gttttctctt atataggtat ttatggtagt tctagaaaaa
   117421 atatttttcc atacagcaat tatctttctg tttaactttt ctgatgatgg aatgtcatta
   117481 ttttcattta tggaatgtat aatttctaaa aacttttcat cataataatt gattatttcg
   117541 cagataaaac tttccttagt ttcaaaatgc ttgtaaaaag tagctttaga cattttacac
   117601 tcttttacaa catccgatat tgaagtattt tgaaaacctt tttggtcaaa aattttttgt
   117661 gcaatagtta taatgagcct ttgtttttct gtcactttat tatctccttt cacgcaaaaa
   117721 cgtttagtac tatatagtac ctacaagttt tgataaatat attatacatc atttggaaaa
   117781 aaaatcaata tatagactgt aatatgaaat ttttgaaaaa tttgttgtta tttttagtcg
   117841 tataaaaaag aaacttaaga gtttcttaag aattgtttaa agaagttgca ataaattagt
   117901 ggtatgatta tagtatgaaa gagaatgtct tgaaattttt ctgtatcaaa ttccaattat
   117961 ggaggtgtag tatatgaaaa agaaaatttg tgtagcaata atttttgctc tatttatagt
   118021 ttttgtagaa atgtttattg atagctctag cgaaggaagt aaaattatga cagctgaatt
   118081 aagtaaatac aggaaaggcg taaatgtatt atcaataaac aatattatag tagcgaataa
   118141 aaaatatagt ttgcccaaag attattctcc tcaggaaagc agtgaagcga gagatgcttt
   118201 ttataaaatg aataaagatg ctcaaaagtc aggattaaat ttaaaagctt ttagtacata
   118261 tagaagttat gaatatcaag atagattatt taagtcatat gtaaaagaac atggagaaaa
   118321 agaagcaaat agattttcag ctaaacctgg agagagtgag catcaaactg gacttgcttt
   118381 tgatattgga ggagatgacc agtcttgttg ggcaaataaa aagttcaaca atacaaaaga
   118441 agctaagtgg ttgtatgaaa atgcatataa atatggtttt atacttagat atccagaagg
   118501 taaagagaat ataacaggat atatgtatga atcttggcac tatagatatg ttggaactga
   118561 acatagcaaa aactttgcaa tgaataattt gactttagaa gaatatttac atataaatta
   118621 agagatggtt tgttaaaatt aggttaaaat aaaaaataac ctagactatt agctgtgtaa
   118681 agtgatataa tgtaaataca atttaagata actactcgaa ggggagtagc ttacacgaaa
   118741 gtggtaatta atcgtcaaga cagtagaaat actcggttaa ttagcaaggg attccttgat
   118801 agcaagacct tcaaaataag cattaggtat gtttgttttg gggtcttttt ttattcaagg
   118861 aatttttatt taaaaaaatt taaatttcaa gtatacataa gagcccccaa acataaaata
   118921 aatttattga agaggagggc aacaaatgtc ttacaaaagt acttatcaag aagtaattaa
   118981 aaatttagac tcaagtttat ctggtttgag taaagaaaga gcagaagagt tgttagaaaa
   119041 aaatggagct aatgaattaa aagaagcaga taaggttcct acttataagc ttttcctaga
   119101 aagttttaaa gacccattag taataattct attgatagct gctttagtac aaatattttt
   119161 aggtgaaaca gtggagtcta taataatttt tgcagttatt attataaact ctgttctggg
   119221 tgttgtacaa acaaaaaaag cagaaagttc attagaaagt ttgaaaaatt tatctgcacc
   119281 aaacgcaaag gtaataagag acaataaaaa aatgacaatt ccagcaaaaa atttagtagt
   119341 tggagatatt gtattcttag aagctggcga ttacatacca gcagatggaa ggcttataga
   119401 agcacaatct ctcaaggttg tagaagggat gttaactgga gaatcagaac cagttttaaa
   119461 gcatacagaa aaaataagtg aagatgtaag tttaggtgac cagaaaaata tggtatttag
   119521 tggtgctgta gttgtttatg gtagaggttc ttttgtagtg actggaacag gtatggatac
   119581 tgagatgggt aaaatagctg ggcttttaga aagtgctgaa aataaactta caccattgca
   119641 acaaaaaata gaggatttta gtaaaaaact tggtgtaggt attgtaatac ttgctctttt
   119701 aatatttata attcaagtag caagaaatta ctttatggct ggaaatggag aaatgacaca
   119761 aattatttta gattcattca tgttctctgt agcagtagca gtagcagcta taccagaagc
   119821 tctatcatca atagtcacta tagtattggc tgttggaaca aatagtatgg caaaaaaaca
   119881 agccataata agaaaattac cagcagtaga aactttaggt tcaacaagtg taatatgtac
   119941 tgataaaaca ggtactctta cacaaaataa aatgacagta gttgattatt atatgtatgg
   120001 aactaataat gatgagttag ataaagaaaa agtaaactat tcttatcatg ctaaattatt
   120061 gactatggtt tctacattgt gtaatgactc tcatataact agtgatggta aagaagttgg
   120121 tgacccaaca gaagtggctt taataaatta ttcaagtaaa aatgatttag attatgataa
   120181 attaagaagt aagtatatca gaataaatga aataccattt gactcagaca gaaagcttat
   120241 gtctactgta aatagtatat atggagatta tataatgttt acaaaaggtg ctccagatat
   120301 tgtgtttagt agatgtaaat atgctttgaa aaatggttca aaagtagata taacagatga
   120361 gataatagaa gaatataaac ataaaaatga agagttctca aatagagcac ttagagtatt
   120421 agcttttgca ataaaagatg tcccagaaga agattttata ccttcaattg atgacgaaca
   120481 tgacatgaca ttggttggaa taatggcaat gatagaccca ccaagagaag aagtaatgga
   120541 tgcagtaaaa gaggcaaaga gtgctggtat aaaaactgtt atgataactg gtgaccataa
   120601 aacaacagca gcagcaattg caaaagagat tggtataatg gaagaaggag acttggctct
   120661 tactggaaaa gagcttgatg ctttgagtga agaacaacta tatgaaaaac tagaaaatat
   120721 aagtgtatat gccagagtct cgccagaaaa taaaattcgt atagtaaaag catggcaaca
   120781 taagaataat ataacagcaa tgactggtga tggtgttaat gatgcacctg cattaaaaca
   120841 agcagatata ggaatcggta tgggaagtgg tactgatgta gcaaaagatg cttctgctat
   120901 ggtattggtt gatgataact ttgcaagtat agtaaatgct gttgaagttg gtagaacagt
   120961 atacagtaat ataataaaat caattactta tctatttgca ggaaacttag gagctatagt
   121021 atccatagta tttgcagtgt ttgcaggttg gtcaaatcca tttacagctt tacaactttt
   121081 gtttataaac ttagtaaatg actctttacc agcaattgca ttagggtttg aaaagtcaga
   121141 aaaaaatata atgaataaac ctcctagaca cccggatgaa agtatactag caggaggaac
   121201 attgaaggca gttgctataa gaggttgtat aataggtgta gttacaataa ttgcacaata
   121261 tataggatta caagtatctc cagaacttgg agtagcaatg gcattttcaa cattgatatt
   121321 agctagaata atgcaaacat tacctgcacg ttctaataat caaacagtaa taaaattagg
   121381 ttttttcagc aataaatacg ttataggagc agttttagtc tgtcttgggc tttactcttt
   121441 aacactaata ccagtgctaa gaggaatatt ctctatacca acaacgtttg gattgtacca
   121501 gttggggatt tgcctagggt tagcattaat ttcatcaata ttaatggaac ttaacaaatt
   121561 aataaataga agtgaagtaa aataatcaaa aaattaaagg gcatattgat tttaacaata
   121621 tgccttttat aaatagtcta atttattcta tattatcgat tatttggaat gcttttataa
   121681 cttcaggtaa ttctttttct tcaggcattc taaatcttat gaaattttta tcaagtccag
   121741 taaaatcact tccagatata actcttattt ttaatttagc aaactcttgt tgtaaatcta
   121801 tgtccttgtt tttatgttca actgtcataa ttgatacagt atcactagtt tcagctatat
   121861 taaggttttt ccatggaatt aataattgat tttttatatc ttttgttttt tcttttaatt
   121921 cttctataaa ttgaacatca tctaataaat ttgctgcaat actacgagat atttcagaca
   121981 cttcgtaagg agtagaaatc tttttaatag ggctaacaag ttgttctgga agaactgcat
   122041 atcctgctct tagtcctgct aaaccaaatc cttttgaaaa tgtttttaaa gcaattacat
   122101 tatcataatt atttagaagc ttgacagctg aattttcttt tggcatgtat tcaccataag
   122161 cttcatctac cataactgct atatcatatt tagctgcttc ctttactata ttttcaattg
   122221 atgataaagg tataatttgt cctgtaggat tgtttggatt gtctatgtaa attactttat
   122281 attctggatt tattttttca ataaattctt tttcattaaa cttgaaatta tcctctttct
   122341 ttaaaagaac ataatcataa gttgcaccat gcatttttat atctgtctca tattctgaga
   122401 actgaggtga atatcctaaa actttatctc ccttttcaat aaatagtcta tttaaaaggt
   122461 aaataacatg tatagaacca tctgccaaac aaattctgtc agtatctaat gctataaaat
   122521 ctttccaata atcaactata ttatctttta aagcaattga atgaggatat cctcttatca
   122581 tatcaaattt taaagcatta aaagcttcta cagctttgtt tgagtaagac acggtattta
   122641 taccttcacc acagtctatc tcgaatacat cttctgaatg tccagattct attgcataac
   122701 tttttttcaa ctgcatttca atagctttgt taatttttag tttcatactt tatcactcct
   122761 tatttagtca ataataaatg ttataaaagt tgctagattt aaaatattat gaaaatatat
   122821 aatagtaaaa aatgaatata aatattataa tagctcactt tatttaatat gattatatat
   122881 catatattgt aaaatttcta gcattataag actataaatt gaaaatattc agaaaaatac
   122941 tacaagaaac gatttatttt gctcttaaaa taagttaaat gaatgttatt aattttgtaa
   123001 attgaaatag tttaagtata aagttatgat ataatctaat aagggtaatt ctttagatta
   123061 tattaaggaa atataggtat acaataaaaa gttatggagt tggattatgg gatataaatt
   123121 aattgtaaca gatatggatg gaactttatt aggcaataat cataaagtta cagatgaaaa
   123181 taaaactgca ctacaaaaag ttataaaaag cggtattaat gtaactttag caacaggaag
   123241 agccttcgat tcagctaaat gcaatgtaga ttttcttaaa gaggacatgc caataatagc
   123301 ttgtaatggt tcattaataa gagagcaaaa tggaaatata atatattcaa ataagattga
   123361 tacaagaaca tgtttaaaca ttttagatgt attagataaa tacgatattt actaccaatg
   123421 taatagtata gattctatgc tttcgaaaaa aatagaagga cgtgaagata gattaagtgt
   123481 atttttaggc tctgaaacag aagtaattgt aaaagatgat ttgagagaag aaatctttaa
   123541 aaaagatata ctaaaatttg taatcataga agaaaaaaat ccatctattt tggatgaaat
   123601 aagaaaagaa ttgagaaaag ttcaaggaat aaagataact tcttcatggc caaacaatat
   123661 tgaagtcatg aatgaaggtg ttgataaagg taatgcagtt aaaattttag ctgaaaaaat
   123721 gaatatagac agagaagata taattgcatt tggagacaat tacaatgaca tagaaatgat
   123781 aaagtttgct ggtcttgggg tagctatggg aaatgcagaa gaattgatta aacaagaggc
   123841 tgattatgtt acagatacaa atcaagacag tggggttgca aaggcaattt ataaattcct
   123901 agagttaaaa gaatcactta gctcttaaaa cagtatataa taggaaaaaa taggttgact
   123961 attttgtaga tagtaattat aatacaaata gataaaacat aaaaatttag attcagtgaa
   124021 aaagagagta gatatagaga aaatctcagc gaattggggg atggtgtgag cctaatgata
   124081 acactttata ttgaaaagaa ctttggagaa tactacttga aattcagtat ggtagtaggt
   124141 aatctcgcct taagagaata gagtgggtaa acattgttta ccaactagag tggtaacacg
   124201 gaatatttcg tctcttggtc tttttgacca agagattttt tagtttcatt gagttacaag
   124261 acttataatt aaaatacaaa aaattaaaat atgaggtgaa agttatgaaa ttatggggcg
   124321 gacgctttag aaaagcggaa aatcaactta tggaagaatt taataaatct tttggctatg
   124381 attgtgtact gtacaaaaaa gatatcgaag gaagtgtagc acatgttcat atgcaagtaa
   124441 aatgtggact tttaacagaa gaagaaggaa agtctataac agaaggttta aaagggatac
   124501 ttgaagatgt agaaaatgga aagttagtat tggatggaga gtatgaagat atacatagtt
   124561 ttactgagat aaatttaatt caaagaattg gagatgttgg caagaagctt catacagcac
   124621 gtagtagaaa tgaccaagtt gcagttgata tgagattgta tgctaaagaa aaagcaaatg
   124681 atttggtgga tttaatatct gaatttaaag ctactataaa agatgttgct gacaaaaacc
   124741 cagtgatgat gccaggctat actcatcttc aaagggcaca agtagtgaca tttaagcatc
   124801 acttaatggc atattatagt atgtttgata gagatgagaa aagaataaaa aatgctatag
   124861 aaatattaga tgaatcacct ttaggctgtg gagctttagc aggaactacg catgatatag
   124921 atagaagtat aacttgtgaa caattaggat ttaaaaaagt agtagataat tttatggatg
   124981 gagtaagtga tagagattat ttactagagc taatgagtga tttttcaatt ataatgatgc
   125041 acttaagtag attaagtgaa gagttgatac tttggagttc tcaagaattt ggatttgttg
   125101 agatagatga tttatataca actggaagta gtataatgcc tcagaagaaa aatccagatg
   125161 gtgcagagct tataagaggt aagactggta gagtatatgg aaacttattt ggtcttttta
   125221 cagtaatgaa aggaatacca ttagcatata ataaagacat gcaagaagat aaagaaggtt
   125281 ttttcgatag tgtacatact cttgaaatgt gtatacaaat aatggataga atgatagcca
   125341 cactaaaggt aaatgaggat aaaatgaaac aagcagtaaa aaatggtttt ttaaatgcaa
   125401 cagaagttgc ggattatttg gttaaaaata atgttgcttt tagagatgca catggtatag
   125461 taggaagtat cgttatatat tgtgaagata ataaaaaagc aatagaagat ttaacattag
   125521 aagaattaca taagttttca gatgctttta aggaagatat ttatgatttt atcgactatg
   125581 agagtatatt aaataaggga ataaaaaaga atttaaaata atgtatttat ttttaaaagc
   125641 tgtaaatttg aatgttatca tttaaattta cagcttttta ttgtgtaaga ttttattata
   125701 taaaagtaag aaacttaaaa ggagtagtat ttaaaataaa tacaaataaa aaattattat
   125761 taaaatgata attaatatca ataagtattg acaaagttat ttctaaatac tattatatat
   125821 aatataaata ataatgaaaa tcaatatcaa ataaatggga ggaaatctaa tgaacttatt
   125881 agtgattggt ggtcatgaaa gaatggaaaa agattatatg gttatggcca agaaaaaagg
   125941 ttataagaca aaggtatata ctaccatgtc atctaaatta aataattcta taggaaaacc
   126001 agatgcagtt gtcatactta catcaactgt ttcacataag atgtctagaa cggttgagtc
   126061 tcaagctaaa aaacaagata tattaatcgt aaggcataaa aatagtagta aggtagcatt
   126121 taatgaatgt ctagatatgg ttgatgaatg tctgggaaat tgttcaaaat gtaagcttaa
   126181 agacaaacaa aaacaaaaaa atatataggt ataaaaaata cataaacata aaattaaaag
   126241 tactgagata atagttataa ttattatctc agtactttta gatttataag gataagtata
   126301 gtataaattt tttattataa tttccaacta cttgttactt tttcatattt tttttacttc
   126361 tagctttttt tctttttttc ttctttatat ttgaagctat tataaataaa actaaaagca
   126421 ctagaatacc tgcaataatc ttaacaaaag tcattaaaac attattttca gtcaaaaatg
   126481 gaagactgct atcaagatta ttttttgcaa ttaagtctat actgttttct agtttaccat
   126541 tattatatac atttaaagta ccaaccttag ctcctttttt tataggcaaa tcaattttat
   126601 ttaactctgt tttggtatca taattgcctt gagattcatc tttttctaag aatatcctat
   126661 aactattttt tggttcataa atcaattcat gttgttttgt aaacaatact tttttagtat
   126721 ctgtgtattt ttctttatca acaatagtag cacacttaaa gttatcaaat ccataatcaa
   126781 tcagaatacg tgagtctaaa tataaatcag cattagttga attaaataca gcaacgataa
   126841 ctcttctgcc atcttttaca gcactcgata aaagacattt accagcagca tcagtatatc
   126901 cagtttttat accatcaact atatcatatt ttatatttat aggttgacct ttgtatgtaa
   126961 tcttatcatg tgatgtcaaa aacttattag tgtttacaaa gtatctctca taaggatatg
   127021 cttttgtagc ttcaaattta agtgacttag tttttacaat ttgtctaaaa gtatcattat
   127081 tcatagcttc tctagctatg agagccatat catgagctgt tgtgtagtga tttgggtctg
   127141 gtaatccatg aggattatta aaatgagtat tagtagctcc aatttttttt gcctcagagt
   127201 tcatgaggtc aataaatttt tgtacattgc caccaccaac atatctagct aatacaaaag
   127261 cagcatcatt agcagaatga accaaaagag catctagtaa ctgctttaca gtaaaagatt
   127321 ccccattttt tagatacata ctagagccat ctatttgagg taaatcttta atttctatta
   127381 cttgatttaa atctttaacc tcctttagaa ctaaacaagc tgtccatact ttagttgttg
   127441 aagctggata aagcttagaa tttccatcct tattatatag tattttgcca gactcatagt
   127501 ccattaaaac tgcatgttta gcaactatag ctggttcatt atctgcaaaa gagatattag
   127561 agcttcctaa aaatgaagta aatatcaata aacagattaa taaaagtgat aaatttcttt
   127621 tcattgtgag cctccaaatt ttaaattcat cttttagtat agcatatatt tgtcaataat
   127681 taaaagaaag gagtgattaa tatatgaaaa aaaaggtaaa atttatttcg ttttttgttt
   127741 tatttatttt aataatatca tcaataatcg tttataaatc gcttattttc aaagatgata
   127801 tttatgttgt aagtaaaaaa aatttaccta atgaaaaaac acatgttgta gagaatgaaa
   127861 ttaaaggtga agataataat cacagtaaag taactaaaga catagataaa aattttcaaa
   127921 ataataaaat aactatatac ataagtggag cagtaaatag acctggaatt gtaactatag
   127981 agtcagacaa gagactttat gatgctgtag aattactagg aggaacgaca aaagaagcag
   128041 atttaaatgg agtcaatcta tcagtaagat tagaagatga acaacattac ataataccta
   128101 aaataggtga agcaacatct gttacaagta atgatgattc caataaacta aatcagaaga
   128161 atgagtcaag aggtgagcct aaaaataaat ccaataaaaa tatatctaac gaatcaaaag
   128221 taaatataaa tgtagcgacg atagaagagt tggattctct acctggggtt ggagaagcta
   128281 cagccaataa aattttacaa cacagagaag aaaatggaca gttcagttca attgaggaaa
   128341 taaaaaatgt aaatggtatt ggagataaaa agtatgaaaa tataaaagat ttaatttgtg
   128401 tagactaaaa tataatacaa aacttacata tagatatgtt attataaata tgtatgtata
   128461 tgtgtgtaca tgtggaaatt tagtaaagga ggcactttta tgaaaaaaga acaaaaaaaa
   128521 cttacagaga tgacaacagc aggtggttga gccgctaaaa tagggccaga ggttctggca
   128581 tcagttttat ctcaattgcc taaaaatgat aatatagaaa atttattagt aggactagat
   128641 acagcagatg atgctgcagt ttataaatta aatgatgata tggcacttat ccaaacttta
   128701 gacttcttta caccaatggt agatgaccca tacgtatttg gtcaaattgc tgcatcaaat
   128761 tcactatcag atgtatatgc tatgggaggc aaacctttgg ttgctatgaa tattgtttgt
   128821 tttccatcat gccatgatat ggatgtactt gcagaaatat taaaaggtgg gtttgataaa
   128881 gtgaaagaaa gtggagcact tttggttgga gggcatactg tagatgacaa agagcctaaa
   128941 tatggtcttt cagtttctgg gattgtaagt ccaaataaag ttttatcaaa tgctactgca
   129001 aaacctggtg ataagttaat tataacaaaa ccaattggag tgggtgtatt aaatacagcc
   129061 atgaaagaag gtatggtaga acaacatata gcagataaag taatagaaat aatgatacat
   129121 ttaaataaat atgcagcaat gagttttgag aaatttgatg taaattcggt tacagatata
   129181 actggttttg gtctacttgg tcatacttta gaaatggcca aagcttctga agtaagtatt
   129241 gaaattgaat caaaacatgt accaattatt gaaggtgcaa tagaaatggc acaaatggga
   129301 attatacctg ctggtatgta taaaaatatg cattatgtat ctaaagatgt agaagttgta
   129361 ggaaatatag aagttgcagt tcaagatatt ttatacgacc cacaaacatc aggagggttg
   129421 ttaatttcag taaaagaaga acttgcagag gaacttgtaa aagatatgaa attaaatgga
   129481 gcaatagaag ctaaaattat aggttctgta gttccaaaag gggaaaaata tattacagtt
   129541 ttataaaata ttatagagaa agagtgattg ttttgagcaa aagagaattg tttgcaatgt
   129601 tgccttcagt tgatgaagta ttaagtgata atagaattgt agaaataata aatgaatatc
   129661 ctagaagttt agttttagaa tctgtgagag aagtaataga tttaaaaaga caatttatat
   129721 taagattaaa agaagatgca tcaaactctg taacaataga gtttggtgaa ataatagaat
   129781 ctgcaataga gagagttaag ttaaattact cattatcttt aaaaaaagtt ataaatgcaa
   129841 ctggtacagt tattcataca aatttaggaa ggtctttact tagtgaagat ataaaagatg
   129901 aattatggtg tgctgcttca aggtattcaa acttagaata cgatttggat aatggagaaa
   129961 gaggttcaag atactctcat ttaactagta caataaaaag acttactgga gcagaagatg
   130021 tactagttgt aaataataat gcagcggcag tacttcttgt acttagcaca atggctaaag
   130081 gaggagaagc aattgtatct cgtggagaat tagttgaagt aggtggttca tttaggattc
   130141 caagtataat ggctcttagt ggtgcagaat tagttgaagt tggttcaact aataaaactc
   130201 atttgaaaga ttacaaggag gccattacag aagatacaaa tgtattgatg aaggttcata
   130261 caagtaatta tagaataatg ggattcacag agagtgtttc tatagaagaa ttggttaatt
   130321 taggtaaaaa atataaacta cctgtaatag aagacttagg aagtggagtt tttatagatt
   130381 tatcaaaata tggtttatct tatgaaccaa ctgtattgga ttctattcga caaggtgcag
   130441 atgtagtaac ttttagtgga gataagatgc ttggaggtcc gcaagcaggt attatagttg
   130501 ggaaaaaaga gtatatagaa aaaatgaaga aaaatcaact tactagagca cttagagttg
   130561 ataagcttac aatatgtgct cttgaagcaa cattgagaat gtatttagat gagacaaaag
   130621 ctatagaaaa tatacctact ttaaaaatgt tgacatataa aattgaagaa ttagaagtaa
   130681 aagcaaataa actatttgaa aaaataactg ctttaaactt aaatgcaaac ataaatatag
   130741 aagatggatt ttcacaggtg ggaggagggt ctatgcctct tgaaactata agtacaaagg
   130801 taatatcaat aactcctgaa catatgaatg tttcatcttt agaaaaaaaa ctaagactta
   130861 gtgaagcaca tataatagcc agagtgtatg ataataaata tgtactagat gtaagaacta
   130921 tatttgatga tgaatttgat gtaatagttg aggaattgag aaaagcattt aattaaataa
   130981 atttgagtta ataaatatta aatttagaag tataagtatg aagttttgat taaaaaatag
   131041 ctacacacac ttgtgacttt agtcatagca ggtttagagg gggcaaaaaa tgaaaaatgt
   131101 agtaattgga acagcaggtc atattgacca cggaaaaact actcttataa aagcattgac
   131161 tggaagagag actgatacgt tagatgaaga aaaaaagaga ggtatttcaa taaacttagg
   131221 atttacttat tttgatttac caaacaatag aagagctgga attgttgatg tcccaggaca
   131281 cgaaaaattt ataaaaaaca tgttagctgg agcatcagga attgatatag ttttacttgt
   131341 tgtagcagca gatgaagggg ttatgccaca gacagttgag catttagata ttctaagctt
   131401 tttaaatatc aaaaatggaa tagtggttct aactaagtct gatactgtag atgatgaatt
   131461 tagagagcta gtaaaagaag atatttgtga aaaaataaaa ggaacttttc ttgaagatgc
   131521 tgaaataatt gaagttgatt ctatatctaa aagaggtata gacactctta ttgaaaaaat
   131581 agataaaatg agtgatgata tagaagataa aaatgaaaac tctccagcaa gacttaatat
   131641 agacagagta ttttcaataa aagggtttgg tactgtaata acaggcactt taatagaagg
   131701 aaagataagt atagaagatg atttggttat atatccacag gtattaaaaa caaaaataag
   131761 aagtatacaa gttcatggag aaaataaaga tacagcttat gcaggtcaaa gaacagcaat
   131821 caatatatca aatgtaaaag tggatgatat aaaaagagga gatgttttag ctgcaccaaa
   131881 ctcattggag gaatcaatga tgttagatgt aaaattatca ttggtaaatc atttagataa
   131941 aggattaaag cactgggata gattaagatt gtatcatgga actagagaga tactttgtag
   132001 agcagttcca ctagataaag aattaattga aagtggagaa agtggctatg ttcagttgag
   132061 acttgaagaa agcatagtat ctaagaaagg tgatacgttt gtagtgagac gttattctcc
   132121 aatggaaact ataggtggag gtgtaataat tgacccatct cctaaaaaac ataagaaatt
   132181 tgatgaaaaa gttatagaag cattaaaaat aaaagaaaaa ggcgaactaa aagatataat
   132241 agaagagtac ttaaaaagga atttaaaaaa ttatccaaat ataaaagaaa taatgagcta
   132301 tagtggtgct catgaagaag atgtaaaaag agcgcttgaa acacttatat cagaagataa
   132361 agtatttatt ataggaaata tgtatatgca tataaatcaa tacaataaat taaaagaaaa
   132421 tacaataaag cttttaagtg agtaccataa gaagtatagg cttagaaaag ggatactaaa
   132481 agaagaagta aggtctaaga tagagagtaa ttttaagact agggagatgg atattttatt
   132541 agaaaaattg tctacagaaa atgctataaa aatagaaaat aatatagtat ctctattaga
   132601 ttttgaggtt attttaaatg ataagcaaaa agaaatagca aaaaaaatag aaaaaagatt
   132661 aaaatcatgt ggagtttctt ctatactgac aatagatgaa gtttctgaag gaaatcataa
   132721 ctatgctgaa gtattggagt caatgatagg taataaagta gagaaattag atgatttgta
   132781 tataatggac aaagatattt atgaaaatgc aaagaacatt ttgataaatt atataaaaga
   132841 aaataaagaa ataacattag gagaatacag agatttgatt gattctagca gaaagaattg
   132901 catgattata ttggaaaact tcgatagaaa caaaataact aaaagagtag aaaacaaaag
   132961 aattttgttt tagcagaaaa tgtctgtttt tgctttaagg tataaagaag gaattataat
   133021 gtcgagtatc gtataattaa ttagtataaa atattaatta agaggaagtg taaagtattg
   133081 aagaatataa tacctgatgt aaaaccagat ataaaagaaa gagaagacat gagcctttta
   133141 tttataataa tgggctcagt acttttatta tttattataa aagatataga gaaatatgaa
   133201 actttattac atgccatata tacgatattt ttagtagcta caggagtaat tatatttaat
   133261 actacaaaat ttaaagtaga ttcattttct acatttttag gattaatttt tatagctact
   133321 ggagtattgg agtgtatata tttatttaat tccttgggga ttaaaactaa gtctataatg
   133381 gagattaaca tcacaatatc agcaataaca gatttatttc ctatactggg tgtatactta
   133441 agttttaaat ttgttaagga taacaaacaa atttattcaa gtgtaatttt atttatagca
   133501 actgctacat taacaataac atctttattc ataatatcag gaatttgtga ctatctggga
   133561 aatggtaaat cacaatatgc tttaggagtt ataatatcta tattcataat aattatttct
   133621 atcattagtg gaattgaatt aaattcaagt tcaaataaag gtaaatggga atatgatgaa
   133681 aaaaagattt ttaacagaat aatagtaata ataatcttat caagagttcc aaatctattg
   133741 catatagtta ttgataatag aaatgtagag aggatattat cacaaataat aataaatgta
   133801 gccttatatt atttatataa ttacatagta tctaagaata ttaagaaaac agcactggaa
   133861 ttgcatgata cgaatgaaga attaacaaaa aaaacggaaa gtttaaaaga aaagaataaa
   133921 aaattaatct atgagacaga aaagatagag gaacttaagg gaatacttat gaaaagagaa
   133981 tctaggctac aatctacatt agatgtagca gtaaatagca tagtagtatt tagcaaagat
   134041 ggagaaatta catatgcaaa taagagcttt agaaatactt ttggagacta taaagaacaa
   134101 gataaattga ctgataaaat aaaaaacttc aatgatttga tagaaagcat tcattatgtg
   134161 tttgttcatg agaagaatgc agagaaactt attagtacaa gcgataataa agtttatcaa
   134221 gctatatttg cacctttaat tattgcttca caaacagaag gagtattgtg tgtactagaa
   134281 gataagacta agaaaaagga gtacgaacgc aaacttattg aagcaaataa gagaagtaaa
   134341 gattttttag aaagtattgg agatggcata gtagtgcttg aaggtaataa caaaatatat
   134401 gttaataatg catgtaggga aatttttaaa aataatttag agagtattga tttttcatta
   134461 gtatgtaaaa gtgaagaaag tatagaaaaa agatatgtaa tagatggtga agtaaagtat
   134521 gtagagatga gtttttctca gtatactaat gctggtacta ataaaactat tattgtaata
   134581 cgtgatacaa cctctcgaaa aatatatcaa ataaaacttg aggaaagtca atcatcatat
   134641 tcaagattta tagatatatt acctgatggc atatgcttat taaaagaaga tttaagtata
   134701 aactatgcaa ataagtcgtt tttagatatg ctagctttta caaacataga tgatataaaa
   134761 gattctaata ttaaactatt aatgaatgcg aatactgaag aaaaaatgaa atttacggat
   134821 aatatggcta aagttttaaa tgaaaataga agtatacttt tactggaata tgaattgata
   134881 aatagttatg atgatatagt agaagtagaa ttaagtgcat taccttttgc tatatacaat
   134941 actagataca taatgcttat tataaaagat ttagtacata agaaatattc cgagcaagca
   135001 gaaaaagaac tgcttgaaag atttaaaaca gataaaatca aaacggagtt ttttgcaaat
   135061 atgtctcatg aactaaaaac tccactaaat gttatatcta gttcaaatca actggtagat
   135121 tctttctata gaaatgaaaa gataaaagat tacaataaca atattaaatc tcatgtggat
   135181 ttagttagac aaagttctta taggcttcaa agattaataa ataacattat agatttaaca
   135241 aagatggagt ctgggttcta tacactaaaa cttgcgaaat acaatattgt atctgtaata
   135301 gaagacttat ttatgaatat agaagagtat gcacttagaa aagacataaa aattcttttt
   135361 gatacagacc ttgaagaaat taatgtttat atagacaagg ttgaaattga gagaattatg
   135421 ttgaatctat tgtcaaactg tattaagttt actgataatg gaggctggat atatgtaagt
   135481 attcattata aaatagataa agtaatcata agtgtaaaag acactggagt tggaatacca
   135541 caagataaat tagagttgat ttttgaagaa ttttcacaag ttgataagac tttatccaga
   135601 aatactgaag gaagtggaat agggcttgct atagttaaga atctagtaag tcttcatggt
   135661 ggagatatag aagtagtaag tgaagtgaat aaaggcacag agttcttaat ttcacttcca
   135721 atgaagggat ttagtagtga acattacaca gaagataaga gaatatataa tattcaagaa
   135781 aaaataaaaa tagaattttc tgatatata
//
LOCUS       DAFAZV010000005       128518 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFAZV010000005 DAFAZV010000000
VERSION     DAFAZV010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 128518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 128518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..128518
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.005"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..2356)
                     /locus_tag="KOU88_000556"
     CDS             complement(<1..2356)
                     /locus_tag="KOU88_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBK3210471.1"
                     /translation="MKIPKKIAAMLTVTMIAGSSTAGIASAQTVATNLTGQERYETAV
                     KISQDGWKNADEVVIVNDSSIADALSATPFAKAKNAPILLTSKDKLNDKTKAEIQRLK
                     AKKVYLIGGTSVLSTNIEKEIKDLKISFERISGAERYQTSLELAKKLDAISDVKKIAV
                     VNGEKGLADAVSVGAPAAQNNMPVILADSKNGTAVADKFIKDAGITQSYVVGGESSIS
                     EAVKNKLPNSTRLGGTDRNDTNAKVIKEFYKKTDLKNAYVTKDGMNKQDQLIDALAVG
                     VLGAKNQSPVVLVGKNLSASQKSLVNSKSFDKITKVGGNGNETAFNEMKSLQEVKTVE
                     AKTISELKSAIDKATANDVINFKPTSEVKEAFTIQTDKAVTVNLNGTYTKTVTINMPN
                     GDVNNYAKVDDVVIDDVKDGTFVNYGKITNLKVNDKNGAKIENNSKGEIGSLTVASGA
                     SQVKVTNGGKITTVTNNSKGTTIDNKGTISSVKGDNSPTISGNSPSSNSSGGSSSSGG
                     SSHGGGSSSGGSSSNQTSVNNEAAKITSVPTPAKDATRLTMPSVSSGYTIAIKTSSNE
                     SVIKKDGTIIPPNTATTVKLVFTVTHTSSGKTADTKELSVTVPAKSTDEELQAALDNE
                     VAKITSVPAPAKDATKLTMPSVSSGYTIAIKTSSNKGVIKEDGTIIPPNTEETVTLVF
                     TVTQESSGKTADTGEIDVVVPAKSTDGEIQAEVQAEADKITSVTQPTQDATTLTMPTV
                     ASGYTIKIKSSTNESVIAKDGTIIPPNTETKVTLVFTVTHTSSGK"
     gene            complement(3140..3328)
                     /locus_tag="KOU88_000557"
     CDS             complement(3140..3328)
                     /locus_tag="KOU88_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210472.1"
                     /translation="MNNKKKAFLISGAINVISLIIVFSLFHYNIIENSTQNMIITVIL
                     IFIFEMIKIKIIEKYYKL"
     gene            complement(3354..4493)
                     /locus_tag="KOU88_000558"
     CDS             complement(3354..4493)
                     /locus_tag="KOU88_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBK3210473.1"
                     /translation="MVIKLTIEEYKNKYFTGNKIVLSINSFDNKELYYHETENILNLI
                     NEIDKLTSSKIFKIIEDKNDLALESYYSSVIEGAFSNRKIAKSIIRGKMKPSNKSEYM
                     IYNNHRALEYGLDNLDKLYSHKFIYDLHHILGENCLDSEEYEYRTEKVYVCDSKGEII
                     HIGLEPLKIYDFMSKLIDFMENSKVSNLIKSAIIHFYFVYVHPFSDGNGRTSRALSYL
                     YLIDKGYDTFKEFSISYMISKNRTKYYKAILDVENKGNNLTVFIEFMLKSIIQSINEM
                     RNMHDRKSLESILKEELFENDITLSATEEHILKYICSKDNYSMTLENYIKKNKSRYLK
                     AGIKEIELVDQLMEVFNNLEEIEILSKEKNIYKVNDKYLKMLDID"
     gene            complement(5030..5869)
                     /locus_tag="KOU88_000559"
     CDS             complement(5030..5869)
                     /locus_tag="KOU88_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK3210474.1"
                     /translation="MSDIKNEVSKKTLSKKDVIKSWLRWFFFAQSNYNYERLQSTAFS
                     HSMLPVLKKLYPDKEELKQEVETHLAFFNTEPICGCVIHGITIAMEEEKANGADEISG
                     DGMNAIKTGLMGPLAGIGDTLTQGVITPIVLAVCIGLTEGGASIAGPILFVIAQYIIM
                     TSISFGMWTNGYKYGKKAVESILQGGIVNKVIEGASILGTLVMGGLVGRFINLSTPIS
                     YTSGDFKFSLQTDLLDKIFPGLIPLVLTLLVLFALKKGLSPIKIMCILIVVGAITGIL
                     GLF"
     gene            complement(5893..6651)
                     /locus_tag="KOU88_000560"
     CDS             complement(5893..6651)
                     /locus_tag="KOU88_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3210475.1"
                     /translation="MHISLIQAVLIAIFYYLSWSPWLTYVGFFTWNRPLLAGFVTGII
                     LGDPVQGAIIGAGINMIYLGFISAGGAQMGDPAFAGYVGTALAIASKLDVSTAMAIAV
                     PLGTVATVLWIGKMTVNSFFAHWADREVQKGNVDRVAFINIVPPQILLFAMSFIPALL
                     VVYFGPNAIDGMLEVMNDNVLHVFNVIGAMLPALGIAMNLKLIGNKFTMPFFILGILM
                     AVYFKVDIIVISVIGVILALTITSIKYGKDSATS"
     gene            complement(6698..7171)
                     /locus_tag="KOU88_000561"
     CDS             complement(6698..7171)
                     /locus_tag="KOU88_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210476.1"
                     /translation="MSNIALTRIDDRLIHGQVITAWCKITSAKRIVIVDDLVVKDPFI
                     VQVLQMAAPSTVKVEVHDVESGAEVLKSHNGDENLIVLVKYPKTVLGLVNSGVDLKEL
                     NVGGMGAGLGRKSFYKNISVSDEEKEIFRELISKDVKCFIQIVPDAKKIDVGTLL"
     gene            complement(7200..7616)
                     /locus_tag="KOU88_000562"
     CDS             complement(7200..7616)
                     /locus_tag="KOU88_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3210477.1"
                     /translation="MIHMAGIIIATHGNMAKAMLESAELIVGKQENVETLGLNHGDSI
                     DEFSRKLEDGIEKYKDEGVLVLLDFYGGTPFNTSAIIINKFAKVCELECLTGVNLPML
                     LELFLNRDTMKLKDLKNLCEEVGISGIKDVKTVLKL"
     gene            complement(7663..8715)
                     /locus_tag="KOU88_000563"
     CDS             complement(7663..8715)
                     /locus_tag="KOU88_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBK3210478.1"
                     /translation="MKSVRFYGIRDTRVEDVDVPKILEKDDVIIKVKVAGICGSDISK
                     YSKTGPHMVGEILGHEFSGEVAQVGKEVRSFKIGDRVAVCPAMPCFECDECKKGLYSR
                     CNNVAIIGNKELGGCFAEYTKVKERNLIKIPDEISYETAAALEPVCIAGHGLFRSEAK
                     VGDTVVVLGTGPIGLFSIQWAKIFGSTKIIAVDVFDEKLDLAKELGADICINAKEKNI
                     VEEIKRLTDGDGADIVIESAGTPLTCGQVLLLAKKGGTVLYAGVPYGDVALTREQFEK
                     IVRSELTVKGTWFGNSFPFPGKEWSAGLYHMQKGDMNVEKLVTHRINLEEVPAYFEKV
                     YKRDIFFGKIMINIDN"
     gene            9111..9791
                     /locus_tag="KOU88_000564"
     CDS             9111..9791
                     /locus_tag="KOU88_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBK3210479.1"
                     /translation="MKKVYQGKTKDVFELDNGNYLLKFKDDVTGKDGVFDPGENSVGL
                     SIDGIGRANLETSVKFFEILNNAGIKTHYVSANLEEATMEVLPAKVFGNGLEVICRYR
                     AVGSFLRRYGSCVEEGAKLDCYVEATLKDDDRCDPLITSEGLEALNIMTQAQFDSMKS
                     MTQKISNIVRDTIAEKGLELYDIKFEFGFYNDEVILIDEIASGNMRVYKDGVIVDPMD
                     LTALLLDK"
     gene            complement(9924..10244)
                     /gene="sugE"
                     /locus_tag="KOU88_000565"
     CDS             complement(9924..10244)
                     /gene="sugE"
                     /locus_tag="KOU88_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBK3210480.1"
                     /translation="MKWLFLFVAGLFEVFWAFQLKNSHGFSKLTPSILTVVGMIVSFY
                     FLSLALKHLPLGTSYAIWTGIGTVGTAIVGMAILNEPISISRIACIGFIVVGIVGLKL
                     LSTN"
     gene            10626..11453
                     /locus_tag="KOU88_000566"
     CDS             10626..11453
                     /locus_tag="KOU88_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBK3210481.1"
                     /translation="MNFYKIAVCQMITTENKIENINHAVDMVTEAAINGSKIVVLPEM
                     FNCPYENKYFPKFAEEYPGETTTILSKLAEKHGIYLVSGSIPELEDGKIYNTCYVFDK
                     NGALIGKHRKMHLFDIEVTGKVSFKESDTLTAGNDVTVIDTEYGKVGIAICYDIRFPE
                     LSRLMALKGAEIVILPAAFNMTTGPAHWELSIRMRALDNQIFYVGAAPARNMNASYIA
                     FGNSRISDPWGRIIAQADEKECIIYADIDRDLIPDIRQQLPLLKHRRTDLYELNTLK"
     gene            12275..12949
                     /locus_tag="KOU88_000567"
     CDS             12275..12949
                     /locus_tag="KOU88_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210482.1"
                     /translation="MNNKILVVDDEEGIITLLKDYFEMNGYEVYTAQSGKDALKKISK
                     NPDIILLDINMPEIDGIEVCNRIRDYVSCPILFLTARIENTDKINGFRAGADDYIVKP
                     FDLDELGARVSAHLRREQRKSNQTKIKFYNDLTIDYEKRLICIYNNQISLSKKEFDIV
                     ELLSMNPGQVFDKEKIYDRVWGYNSNGNSDVIMEHIRKIRIKLSKHTLENYIETVWGV
                     GYKWIK"
     gene            12937..14097
                     /locus_tag="KOU88_000568"
     CDS             12937..14097
                     /locus_tag="KOU88_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK3210483.1"
                     /translation="MDKINNMSLKKAFFVLTLSSLIIASVLTTFAYILLNNLYNSIQD
                     KYLKTPINTGIITIVQNNVNQFSDYDKTLLNIINILQLVLPLIFFIGLLLLADIIFYK
                     VKLKTPIEILNKGAMEISNNNLDFCLEYNNNDELGNLCNAFEKMRSELNKNNIKMWTM
                     INDRKQLNAAFSHDLRNPLTVLKGYSNYLTKYIPTGKLSDEKILSTTQLMSEHINRIE
                     YYVENMSNAQRLEDLVVSKSMSNINKFIENLDENISIIAKQEGKSFTLKNQINNINLF
                     FDENIILRVVENIISNAFRYARNNVSILIYLEQELLTFVIEDDGIGFSKESLKLALRP
                     FYRDKTLNDSNAHFGMGLYISKILCEKHGGSISIENNSTNSAKITAKFSTRN"
     gene            14314..14841
                     /locus_tag="KOU88_000569"
     CDS             14314..14841
                     /locus_tag="KOU88_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014118918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBK3210484.1"
                     /translation="MKSFANNITFSRIVFALLMLSFTFCSLPFWICYFWCGISDILDG
                     LIARKLRQQSGIGAKLDSIADFIFSVTILVTVGKNIALPMYLWWCIIAIALLRLISYS
                     IGFFKYRTFSSLHTLMNKITGISIFAFPLLYICFGLDVAGIMICIVAFLSSFEEIAIM
                     IKSKELNRDIKSIFM"
     gene            15127..15795
                     /locus_tag="KOU88_000570"
     CDS             15127..15795
                     /locus_tag="KOU88_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210485.1"
                     /translation="MIIKAKQLSKIYGSNNNKVIALNNVNLEINSGEFVSVIGPSGSG
                     KSTLLHILSGLDNPTSGQVLLDDKDIYKHTEKELSALRRKSFGFVFQQFNLLPVLTAS
                     ENISMPVLLDKKQPDKGYLNEISSLLGIADRLNHLPHELSGGQQQRVAIARALIAKPD
                     IIFADEPTGNLDSKSGSEVMNLLIKTSKQFGKTLVVITHDDRIAKLADRKISIIDGVL
                     MEVK"
     gene            15798..18266
                     /locus_tag="KOU88_000571"
     CDS             15798..18266
                     /locus_tag="KOU88_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210486.1"
                     /translation="MKNYLSLSIKELKSQKLMTTFIIIAIVLSTIMTTVVGQSIGILQ
                     NLRIEQARSFNGDRHVSFHQLTKNQVDDIKKDDRVYQAGTSITIGSSKIKDSGISVLV
                     KEYDKTGLSNYPKLMKLKSGHLPKDKNEIALDENTLKLMGIKPRLGVTIPMNLDISLL
                     NDTIPPYNYTANFKLSGILEDDYTGYVSGIVNGIVGKGTSENLLPKRYTLSSLDFKIK
                     QQEKFQEIVNQLAKKINLSHNSIQYNWIYLNALKIQFEKDENSSNSDGISMIILVSLF
                     VALLVLLASGLVIYNILKISVTKKIKEYGCLRAIGAEPNQIYKIVILQILILCTVAIP
                     IGAVIGIISSKGITGMVTNILNPDILLANDNKEITELIHKNTTAYMFPLVLSTNVSLI
                     FSLISALPSAIYASHVSPKIAMAGSTTKIKRKIKREKTIKNFERHLAWLNLKRNKGRT
                     IITILSLFMSITVFVALSEFSNILDVSRSVSNLKEGDFSLTNEISGFDKSTLDKIAKM
                     KNVNRTSFIKYSEYKQGEIDTDINFENSGEMLKIIGIDEQTLKDLMPSITNSILEDFK
                     NGSICFIKNPIAISTPGVKTRYTNLKPKDSITINKKQLDIYSTVDKMFFLQGNGWING
                     VDVIVYDSVYNTLTNKNKFNQINIYAKDKSKLEQIRLSIEQICENNPGSHWISYIESD
                     KQLKESFKQIEFLAWAVILFVGLIGTLNIINTTHTNINTRTNEIGVKRAIGMSNRSLY
                     KMFLWEGVYYGIFAAIFGSIAGYASAIIINMATIEKLDFTNIPITSILQATIISVLTC
                     IIATLIPLRKVKKMNIIDCIDINL"
     gene            complement(18506..19930)
                     /locus_tag="KOU88_000572"
     CDS             complement(18506..19930)
                     /locus_tag="KOU88_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3210487.1"
                     /translation="MKNQSLITQFRHTFIFIIIASIVATVITYVFALYLYIHSLNKDI
                     YPPNYYERQVPRIEKYINEKNIALLSQSNEEGLKRTIRGDDMLYQVVDNNGNILYGTN
                     PKKLFKTKEELFNNFINKTVRKGGYIHTVPIKGDNGKIEGAVILFYQVKITFANIRGR
                     FVFAVIIMALFSPFLYIVGFTRWLSKRFVKNINQPLHLLIDASKKIKEKDLDFEIDYY
                     SDNELGKLCSAFSEMKDELKGSLSAQWKMEQERVEMVEALAHDLKSPLSIILGYTDAL
                     IGNNTDDNEKLHRYLTVIRENTEKSAALVQKMQYTSDLEKSNIQLNLVPINLPEFLRQ
                     KVQDYELQAHQKEVELILKMQGNIQSPIQIDVDRLTRIFDNIISNSLQYTPSGGNISI
                     TVKDEKNCISYEICDSGRGFSSKDLKKALDKFYRGDEARQTKGGHSGLGLYIVKQLVE
                     QLGGSVKIENSKSGGACVKFWHSI"
     gene            complement(19949..20641)
                     /locus_tag="KOU88_000573"
     CDS             complement(19949..20641)
                     /locus_tag="KOU88_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210488.1"
                     /translation="MSKILIIDDEMDLVMLLEDELKAKGHEVLIAYDGQAGIELSKQE
                     PDLIILDIMMPKMNGFEVCQAIRDDVLCPIIFLSAKQSETDKIKGLTFGGDDYVTKPF
                     GLRELMARIEANLRREKRSQYINEENKRSTLYFGKLCLYMKERAIKIDGKNIDLTKIE
                     YDIVELLALHAGQVFSREQIYEKVWGCDSEGDSSTVVERVKKIRAKFSAVTPEKEYIS
                     TVWGIGYKWNKM"
     gene            complement(20693..21472)
                     /locus_tag="KOU88_000574"
     CDS             complement(20693..21472)
                     /locus_tag="KOU88_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBK3210489.1"
                     /translation="MIKLLSSEWLRAKRTAVQWLTLCMPIIFSLCVVFYLTTKSGSTQ
                     EFAFEGFFTVWTVFIIPIGVGILAGFIVQEEELAGNFNGFLCVGISRVRLYLGKFLFL
                     LFCLTICTFIATLILCIGMSIAVPSGATIWLFLSAAGLVVIGTLPLLAIHLWVSFAWG
                     MGASIGISIGGILMAAILGLTSVGEKVWAFVPWTWPVKLGMLPGIYFIKEAGTISTEA
                     FYSKVMQTASIELIVVAIGLIIFLIGGVIWFKMWEGRKSYE"
     gene            complement(21469..22239)
                     /locus_tag="KOU88_000575"
     CDS             complement(21469..22239)
                     /locus_tag="KOU88_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBK3210490.1"
                     /translation="MNALQSELLKYKRTFMGKLIVFFPVSFAAYAFIMQSTLMQNPLS
                     QTTSWAWQNLLALIFNWWSFLFLPIGFALFATLVAFQEKKAGNYRALRTHNVSPMTLW
                     INKVIAMAVYSFISTLVLIFVTIITGLILKAGPVPFGQIIGASIVCWVVSLAILPLQL
                     WLATWKGMFLSMGVGALGMIFGVLAATKPFWIAVPWSWAVRMVCPIINIHPNGTILEA
                     GDPLLNTSVIPIGIVVSLVVFIVLTALTAAWFNRRDDK"
     gene            complement(22236..22940)
                     /locus_tag="KOU88_000576"
     CDS             complement(22236..22940)
                     /locus_tag="KOU88_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK3210491.1"
                     /translation="MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGK
                     STTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSLIESPALYGNLTAEENLLVHTKI
                     LGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
                     DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDSNEN
                     LEEFFTDVILKGGQNR"
     gene            complement(23176..23688)
                     /locus_tag="KOU88_000577"
     CDS             complement(23176..23688)
                     /locus_tag="KOU88_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210492.1"
                     /translation="MKKISQEKISTHIQEVPQEKIEQWKSLYEKYKSILKVNSKSVLE
                     IIEFLKRKYVIVEETSEEFKHVVINNIKLNKPFSQKISSDKELKPIVFTIPNEGNAKK
                     LYDTQEEIYSGCKIIVGMDFETGCVFVEGSDELNDEITSFKGLDKYDINNYYLVANYI
                     RCLKKYKLID"
     gene            24014..24271
                     /locus_tag="KOU88_000578"
     CDS             24014..24271
                     /locus_tag="KOU88_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210493.1"
                     /translation="MILNRAELFRGYSLNRFNEICNILSVNKIKYKYKVKNNAYSKKP
                     FFNEITLGNLGQKEDFSYEYLIYVHKDDYEQAESLINSKLR"
     gene            24414..25040
                     /locus_tag="KOU88_000579"
     CDS             24414..25040
                     /locus_tag="KOU88_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210494.1"
                     /translation="MKINIKSKLSEFIKQNNLFDDSRIISYLPNITIETDKIKTIMIN
                     EVVPTNTNDDFYSVDKDADYLKTTIPLFDSAGIEVSSINDILDMGIYITNAVKLPKSE
                     YTITRDTIKLHMPILEEEIKLFKNLEVVMLMGDVAKKSFNMITKKHIKKNVIPSISTY
                     KLRNNELYYDNLRVFPSYIMTGGNILIEKSKFEMASEDIKKMFEIING"
     gene            complement(25286..26065)
                     /locus_tag="KOU88_000580"
     CDS             complement(25286..26065)
                     /locus_tag="KOU88_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901940.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBK3210495.1"
                     /translation="MNSKIYYFSGTGNSLVVSNILKETLNGSKEVIPLAIHRKENNID
                     INEDILVIVFPVYFADVPDIVKSFVEKLNFNINTHIYAIATCNGVAGHSLFTIDKLLK
                     KRGKKLSAGFLINMPGNALITPPDVEEERLKNQTNRVAEIAKCINNLEIGNIEGKNNL
                     KSHIDSVVLRLVGKNMQIATTKFFAENKCNGCGTCKRVCPVENISIVDKKPKWGNECE
                     RCLACFHWCPKEAINVKKSFLTNRKKYHHPDITVKDIFLDK"
     gene            complement(26133..26594)
                     /locus_tag="KOU88_000581"
     CDS             complement(26133..26594)
                     /locus_tag="KOU88_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3210496.1"
                     /translation="MGGARDYLNGGKMKDFEKLYEATTKLVSTSLKVKDDLKKMFKQN
                     GYDITTDHYALLRFLWEQDGISQIDLCEKSCKDKSNTTRILDVMKNKGLIVRKVDVKD
                     RRKFQIFLTDLGRELEEPLNEIASIYATETFKSISDEELPLFTDILDRIGK"
     gene            complement(26570..27247)
                     /locus_tag="KOU88_000582"
     CDS             complement(26570..27247)
                     /locus_tag="KOU88_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3210497.1"
                     /translation="MIITVINGSPRKNGATSKVLTYLYKDIERLIPDVKINYFDLSEV
                     NPSYCIGCLNCYKMGKCINQNDKVEYIHDIITKSDGVIFGSPTYGSSVTGLFKVFTDR
                     AHMMLERLLYRKPCIAVTTYENARGSKAISFIKSMVLDSGGYVCGSLSIKTGFNQNPI
                     TEKVESKIQKVSKKFIYCIEEKKNPPVLSQIYNFIAINAVLKPMAFKDIEQYKGIIDR
                     WEEQGII"
     gene            27480..27866
                     /locus_tag="KOU88_000583"
     CDS             27480..27866
                     /locus_tag="KOU88_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3210498.1"
                     /translation="MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTI
                     QTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVATESSSFLNRFYNGTLNSMVLNFL
                     ENDKLSEDDIEELREILNKRTTKGDK"
     gene            27869..29668
                     /locus_tag="KOU88_000584"
     CDS             27869..29668
                     /locus_tag="KOU88_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaR1 family beta-lactam sensor/signal
                     transducer"
                     /protein_id="HBK3210499.1"
                     /translation="MYAPFFIRFLLSTLTLSILIVVILLAKKVFKKHISAKYQYNIGF
                     ILLIMLIIPFVPLKYINLGNVFNYLYTFNQLGSSTNRTSMIKNSPNSIINNSNALNDF
                     SVSLNQVNFDSLNILLLVSWIIGILIMIAITIHCNIKIKNMKKSIQILRDDEIVFIFE
                     KCKKDIGINKDFILCKSPIINTPITFGYFKPHIILPDKSISKLSLKDIKYILLHELQH
                     FKNKDILINYIMCFLQILYWFNPLVWYAFKEMRIDREIACDISVLKKLDKDSHIEYGQ
                     TLINFVDNISRPSNLTLTSDIGGSKKQIKKRLLKIMDFHNESNTLKFKSILIFTLIAL
                     IVFGNIPKLSIMADINEKYRPTNEQTVYEDLSQYFKGFDGSFVMYDLKSKQYHIYNKE
                     KSKTRISPNSTYKIYSALLGLENGIITRNNSHIPWDGKHHSNSSWNEDQDLFSAMENS
                     VNWYFQTLDKKTGLKNIQTYLRQIGYGNYDVSGGISNFWLESSLKISPIEQVELLESF
                     YTNKFKFEDKNIETVKDSLLISKKDGVSLFGKTGTANINGKDVNGWFIGYVEKNENTY
                     FFATNIQSKDYSNGSSASKITLSILNDKKIYNP"
     gene            complement(30023..31897)
                     /locus_tag="KOU88_000585"
     CDS             complement(30023..31897)
                     /locus_tag="KOU88_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3210500.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVFPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
     gene            complement(31902..33566)
                     /locus_tag="KOU88_000586"
     CDS             complement(31902..33566)
                     /locus_tag="KOU88_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBK3210501.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            complement(33580..34401)
                     /locus_tag="KOU88_000587"
     CDS             complement(33580..34401)
                     /locus_tag="KOU88_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK3210502.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            complement(34500..35264)
                     /locus_tag="KOU88_000588"
     CDS             complement(34500..35264)
                     /locus_tag="KOU88_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3210503.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            complement(35261..36010)
                     /locus_tag="KOU88_000589"
     CDS             complement(35261..36010)
                     /locus_tag="KOU88_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3210504.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            complement(36514..37119)
                     /locus_tag="KOU88_000590"
     CDS             complement(36514..37119)
                     /locus_tag="KOU88_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3210505.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            37298..37936
                     /locus_tag="KOU88_000591"
     CDS             37298..37936
                     /locus_tag="KOU88_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3210506.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            38068..38730
                     /locus_tag="KOU88_000592"
     CDS             38068..38730
                     /locus_tag="KOU88_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210507.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            38730..39911
                     /locus_tag="KOU88_000593"
     CDS             38730..39911
                     /locus_tag="KOU88_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3210508.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(40092..42752)
                     /locus_tag="KOU88_000594"
     CDS             complement(40092..42752)
                     /locus_tag="KOU88_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210509.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQVSVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(42749..43432)
                     /locus_tag="KOU88_000595"
     CDS             complement(42749..43432)
                     /locus_tag="KOU88_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210510.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            complement(43776..44729)
                     /gene="blaCDD"
                     /locus_tag="KOU88_000596"
     CDS             complement(43776..44729)
                     /gene="blaCDD"
                     /locus_tag="KOU88_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBK3210511.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            complement(45270..47384)
                     /locus_tag="KOU88_000597"
     CDS             complement(45270..47384)
                     /locus_tag="KOU88_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding domain-containing protein"
                     /protein_id="HBK3210512.1"
                     /translation="MSENKQVVNCDIIASNSKHNMCEYDAELLTFFPDEIAHLIEINN
                     KLDNAFKKAENLVDKLDKDYMDAKMYMVKNRGEIDPHEMFQNEQGLKQIDNYGAFMVK
                     VRDKINKIKDSPYFARIDFRLKDMDDESKYYIGRFAFDYEDELIILDWRSPIASMFYD
                     YEIGKAGYDAPIGWVDGEITRKRQFKIKNGKLEYALESSINIQDDILQKELSHTSDEK
                     MKSIISTIQKEQNQIIRNDKADTLIIQGVAGSGKTSIALHRIAFLLYRFKDKISANNV
                     IILSPNKVFGDYISNVLPELGEEPLCELSFENIAEVQLDRVINFESEKDPLEINDAKW
                     SERVRFKSTLDFVKLIDDYIKQMPNKIFIPKDYTFGSFTAKSDWIQSRFEAYNRYPVK
                     KRLENVAEDIHYKFESDNIMEEDLPKVKSILKSLNGMLTIKNTLTLYKDFFKQMNISN
                     MFVMVEKKTLEWSDVYPFIYIHAAYEGIQEDKIIRHIVIDEMQDYTPIQYAVINLLFK
                     CKKTILGDFGQLVNPNHTHTLDDMKQLYNDGELVMLNKSYRSTFEIINFAKKIQDISS
                     LEPIERHGEEPALLKCNNEQDEINKIKIEIEEFKKSDNATLGIILKTDNDAKAVYDAL
                     REEYSVHLISSESSSFTKGVSITSIKMSKGLEFDEVIVPSVNNKTYYSDYDRSLLYIA
                     CTRAMHKLKLTYTCELTQLIDM"
     gene            complement(47468..48304)
                     /locus_tag="KOU88_000598"
     CDS             complement(47468..48304)
                     /locus_tag="KOU88_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210513.1"
                     /translation="MSYKVINVITAIDYIEEHLSEKLDLDIVANAVHYSKYHLHRTFT
                     TSVGLTMHDYIKRRKLTEAAKLLVFSKKPIIEIALIAGYESQQAFTSIFKAMYKKSPN
                     KYRKEQEFYPLQLRFVLKKDNLFSKNVLELEKEIKLASMSDIPLWMNLVRLVIDGFPN
                     LQEEEYIYQLEQYILEERALILKLNNVAIANMVFNRETRSIDFFGIHPQYRNSDIAQV
                     FLKKVIEDFLIDTDISITTFREGDKADTGHRDMIKKLGFAEAELLVEFGYPTQKFILP
                     LS"
     gene            complement(48899..49261)
                     /locus_tag="KOU88_000599"
     CDS             complement(48899..49261)
                     /locus_tag="KOU88_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK3210514.1"
                     /translation="MKIYDILTRFYIQDIEKAIPFYENLLKEKCSLRFSYKEVGLELA
                     QIGNVLLLSGSDDALKPFIETKSTFMVDSVDEWRSYLLDNGAVVVRDKKKVPTGYNMT
                     LRHPDGTIIEYVQHTKQD"
     gene            complement(49495..49959)
                     /locus_tag="KOU88_000600"
     CDS             complement(49495..49959)
                     /locus_tag="KOU88_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBK3210515.1"
                     /translation="MTRISNITIAEQSEYCFLAIRKTIDFMVEFSEFSKQSFEKISKY
                     LEERGILSSGAPIVCFHNMDLVKLDVEVGFSVATYIDGKNEILQKIVPAQKIITAIDL
                     GPYELQDPTLEDLFSWANSNGYKLHGDIYYQYLNDINRPASEYLTKMMLPII"
     gene            complement(50388..51809)
                     /gene="nhaC"
                     /locus_tag="KOU88_000601"
     CDS             complement(50388..51809)
                     /gene="nhaC"
                     /locus_tag="KOU88_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBK3210516.1"
                     /translation="MKERECRKASLFDAMIPITCLILFLSLGVLVYGSSPHVPLIGAA
                     AVAGLVAVYRLGFKWKELELSMFNSIKMAMQAILIIIIIGVLIGTWIVSGVVPCMIYW
                     GLKILSPNIFLVASTLVCAIVSLATGSSWSTMGTVGVALLGIGQSLGMPIGLIVGSII
                     SGAYFGDKLSPLSETTNLAPAMAGTDLFTHIKYMLYSTIPSLLICLVIYGVIGMKYSG
                     QALDIKQIELIRSTLDSTFNTLSPVLLLAPAIVIGLVVFKVPAIPGLIVGAVLGVLFA
                     VIFQGESMNTILDAAQNGYVSSTQIQEVDALLSKGGIMNMMSTVSLTICALSLGGILE
                     KTGMLEVVASSLLRLAKGVFGTVLCTMVTCTITNIIAGEQYLSIVIPGRMYNKEYKKR
                     GIHPKMLSRALEDSGTLTSPLVPWNTCGAYITATLGVSALTYGPYALLNIINPIVSLV
                     LIACKFKIARIEDEPETCLNFDV"
     gene            complement(51839..52903)
                     /locus_tag="KOU88_000602"
     CDS             complement(51839..52903)
                     /locus_tag="KOU88_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine/ornithine racemase family PLP-dependent
                     enzyme"
                     /protein_id="HBK3210517.1"
                     /translation="MYPRLEIDIEKLKHNAKLISQMCHERNIKISFVTKSFCAQKEIV
                     EEICSEGIDHIADSRIQNLKNLQDINLPKILIRIPMLSELEEVINYCDISFNSELGTI
                     KKLNELCESKNIIHKIVLMFDLGDLREGYFYEEDFFSNVREIVRLKNIEIIGIATNLT
                     CYGAIIPSRENIGRLVSIAKRMEEKFGINLEIVSGGNSSSIHLLINNNMPEGITNLRI
                     GESILLGRETAYGENINGTYQDAFKLICQVVECKEKPSVPIGEIGVDAFRNKPVYEDK
                     GILKRAIIAIGKQDINIDSLIPIDTDIKILGASSDHMILDVSNTKYDYKLGDNLEFLL
                     TYGGIMSSSTSKYVAKKIIV"
     gene            complement(52888..54297)
                     /locus_tag="KOU88_000603"
     CDS             complement(52888..54297)
                     /locus_tag="KOU88_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBK3210518.1"
                     /translation="MENSKVSLKIDVLVAEIGSTTTVVNAFHDINTNNPIFLGQGQAP
                     TTVFEGGDVRNGLSGAIKDLANKLSVDDIEYNDMFATSSAAGGLKMTVHGLVYDMTVK
                     AAKEAALGAGAVIRQITSGRIKRTDLNKIKEINPNIILIAGGVDYGERDTAIYNAEMI
                     ASMNLGIPVIYAGNVENQEEIRLIFEDTNYKLYITENVYPKIDLLNIEPTRRIIQSVF
                     EEHITTAPGMKYIKEMVNENITPTPGAVMEASKLLYKNIGDLLTLDVGGATTDVHSVT
                     DGSDYINKILVNPEPTAKRSVEGDLGVYVNMKNIVEVIGKENLQSELSIDIDAVIENY
                     PPIPKSKEEILFVERLTKEAVVKAMLRHSGKIRNIYGTTGKVKIAEGKDLTEVRYIVG
                     TGGALTRLPSRIEILDNMLKYNKNNELLFPKEKTKILIDNDYIMASMGVLSKKYEEAS
                     LKLLLKSLNFEEERLCILG"
     gene            complement(54297..56501)
                     /locus_tag="KOU88_000604"
     CDS             complement(54297..56501)
                     /locus_tag="KOU88_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892628.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBK3210519.1"
                     /translation="MLKENKKLDIDYILKDLDKYKPKRRGWVWREHLENLEMGPFKYK
                     DCTKPLKKSVGLPSSKYFNNIDPQPSPVITTEIASGRFEDDIRRMRMAAHHGADHLMV
                     IRTAGQSHFDGLIEGTPQGIGGVPITRKQVRAQRKALDFIEEEVGRPINYHSYVSGVA
                     GPEVAVMFAEEGVNGAHQDPQYNVLYRNINMVRSFVDACEAKKIMAFANIAQIDGAHN
                     ANATAREAWKVMPELMVQHALNSIFSEKIGIDKSNICLSTVPPTAPPAPCLKIDLPYA
                     VALRELFSDYKMRAQMNTKYMESSTREATVTHVLNLLTSVLTRADIQSTITPDEGRNV
                     PWHIYNIEACDTAKQALVGMDGLMDMIELKDVGELRDKARELKERAVLYMEEISEVGG
                     YFESVEQGFFVDSGNYPERNGDGISRKIKGGVGEGTVYEREEDYLAPVTAHFGYNNVA
                     QYDENAIDNPSMLIDGCTFENPDKIIYIDELDDFDNVENRLKESYEYRNGTKIKPEME
                     WCADGIVMITMMLPTDKRTAEFAALEFVKKMNLQEIEVISREVMHESEGTRIEVKGRV
                     PFDIDLNNLVIPEEPKVLTDEEIRADIEEKPMKIVSATVGEDEHSVGLREIIDIKHGG
                     IEKYGIECHYLGTSVPVEKLVDAAIELNADAILASTIISHDDIHYKNMKKLHDYCVEK
                     GIRDKVMIACGGTQVTPEIAVEQGIDAGFGRNSKGIHVATFLVEKRREMSNK"
     gene            complement(56495..56869)
                     /locus_tag="KOU88_000605"
     CDS             complement(56495..56869)
                     /locus_tag="KOU88_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine aminomutase subunit alpha"
                     /protein_id="HBK3210520.1"
                     /translation="MKKREDDFEVRRKHLQELSEDELKERFWSLATQIVEPMIELGKK
                     NTTPSIERSVLLRMGFSSLEVKPILEGVMERGLIGKGAGHVVYKLAKSKNITVREAGL
                     LLVKGEYWDEVTCLFREGVESC"
     gene            complement(56947..58377)
                     /locus_tag="KOU88_000606"
     CDS             complement(56947..58377)
                     /locus_tag="KOU88_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent lyase/thiolase"
                     /protein_id="HBK3210521.1"
                     /translation="MNNSTSMKDMSYQAVMGRNNEIMKNAIGLDYSSFEQEGIGFDYE
                     KMMSETGYTLQDIEAIQSQYAVGNTPLIELKNLTKLARKCAKEGKGARIFVKDEAMNA
                     SGSFKARRAATAVYHAKQMGYKGVIAATSGNYGAAVASQAAMQGLKCIIVQECYDSNG
                     VGQPEIIEKARKCEAYGAEVVQLTVGPELFYTFLVLLEETGYFNASLYSPFGIAGVET
                     LGYELAIQFREKYKKDPDIVVCTNAGGGNLTGTARGLIKAGSINTKVVGASVDLKGLH
                     MASDNQFNKKSFTTGHTGFGIPYCTWPDRSDVPRSAARPLRYMDRYVLVKQGEVFYTT
                     ELLAQLEGIERGPAGNTSLAAAFSLAQELDEDKVIVVQETEYTGAGKHICPQLTFARE
                     NGIDIKFGNPREEIAGVNLILPERPELLKCVDIDMNKIRKSFIKNCISNNHIDNIDKL
                     SNRDIEFLMEEVKSSRDFVVDVLNNL"
     gene            complement(58370..58678)
                     /locus_tag="KOU88_000607"
     CDS             complement(58370..58678)
                     /locus_tag="KOU88_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-ketopentanoate thiolase"
                     /protein_id="HBK3210522.1"
                     /translation="MDAKINDWVIIHNIVLTPEERAPQVPEDTKKVSLEMWVKGFIQS
                     DASIGDLVEVKTITGRLVKGNLLKINPYYTHDYGKCIPELLQIGIQAKEILFGGVYNE
                     "
     gene            complement(58822..59889)
                     /locus_tag="KOU88_000608"
     CDS             complement(58822..59889)
                     /locus_tag="KOU88_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-binding protein"
                     /protein_id="HBK3210523.1"
                     /translation="MRKVRVGIWGFGAMGIGMANMILKKEGIEIVSVCSRSTSGKSMY
                     DVLGIERGERPEVIINKNYEEVFREKSVDVVLLATDSFTKKAFDKIIFLLNRKINVIS
                     TAEQMAYPQADDADLAKKMDEVAKENGVSILGTGINPGFVLDLLVLALSGTCEEVTSI
                     KAKRVNDLSPFGKSVMEEQGVGVTREEFIKGVEDKTIAGHVGFVESINMIADGLGWKL
                     DKIEQTKEPIMTTVDRKSKYGEALAGNVAGCRQCGYGYVNGEVLIEMEHPQQIIPEAE
                     GIKTGDYVSIKGIPNIDLQINPEIPGGVGTYAMIVNSIPLIINARPGLKTMLDIPVPR
                     AIMGDIRNQIEVELEEESKAN"
     gene            complement(60144..61517)
                     /locus_tag="KOU88_000609"
     CDS             complement(60144..61517)
                     /locus_tag="KOU88_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBK3210524.1"
                     /translation="MNEILENIDEGVHFVNKDGKTIIYNNSVQKMEKMNRHDILTNSF
                     FDIVNKMKINRSTLLEVLEKREVIKDNIQKYLDKNGKEITAINTTIPIDIKGEFVGAL
                     EISKNMTTIENLLNRNYKKNLVNKVSSRQKKGYEFDDILGESNLIKEAIAKSKKACKS
                     DASVFIYGETGTGKELFSQSIHYGSNRRNYPFIAQNCAALPESLFEGILFGTSKGGFT
                     GAIDRPGLFEQANKGTLLLDEINSMPIMLQAKLLRVLQEGYVRRVGGTKDIPIDVRII
                     ATTNESPKVILNEHKMRKDLYYRLNIIHIKIPPLRDRKEDIPLLCKKFISKYNKKLNK
                     KVVGISDEAIKILKNYDWQGNIRELENIIYCTMSMMEDEVQIETSMINLNDYYNLKEN
                     KESNNYSLNDLEDKTLSKIISEIEEKYIYESLEKASYNITKAASILGMNRQNLQYKIK
                     KYNIKIL"
     gene            complement(62060..64018)
                     /locus_tag="KOU88_000610"
     CDS             complement(62060..64018)
                     /locus_tag="KOU88_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2075 domain-containing protein"
                     /protein_id="HBK3210525.1"
                     /translation="MKRAYYSSSVNEFIVKDIFTIFGEITCNDQFAADDLQKNTWKKE
                     IGILKRELSTFKDGHLLFEYTIPRIGSRIDNVLIYKGIVFLLEFKVDEDTYPKHAIEQ
                     VTDYALDLNCFHKESHDKLLVPILICTKAPQKDQRIRMMKENILETYCCNEFNIGKYI
                     KKICTTYNRSSFNSDTWINSLYMPTPTIIEAAQALYMGHNVEDISRNDASAKNLNQTT
                     KAINKIIDYSKTHNRKSICFITGVPGAGKTLAGLNIAIERQKVDENEHAVFLSGNGPL
                     VDVLQEALARDDVTRNGIRKSEAIRKAKEFIQIIHHFRDEAISVDTPPIERVTIFDEA
                     QRAWDEPNLTNFMKRKKGVLDFNMSEPEFLISILNRHIGWATIVCLIGGGQEINKGES
                     DGISGWFESLRNNYSDWDVYISNKIIDEEYSKGNSFDELTEGVNYRIIDDLHLSVSLR
                     SFRSENVSTFVKAVLDVDKVAAKELYNQFKKDYPICVTRDLELAKKWVRDKSKGSQRY
                     GMTASSGAKRLRKYGVWVQNKIDATNWFLNGKDDVRASYFLEETATEFDIQGLELDWT
                     IVCWDGNLRFKNNHFEYYNFNGTKWQNINKEDNILYLKNAYRVLLTRARQGFIIFVPI
                     GDESDITMQPNFYNGVYEYLKEIGIEEL"
     gene            complement(64211..65401)
                     /locus_tag="KOU88_000611"
     CDS             complement(64211..65401)
                     /locus_tag="KOU88_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HBK3210526.1"
                     /translation="MDKNKYKIETLMNHVGENLDGDYGAVNPPIYQSSIFARSTYEDI
                     EAYFEGSKDGYLYSRTKNPTNDILEAKLSALANAEASITFGSGMGAISSAILHFVKNG
                     DHIIASNNLYNPTMNFITKELKEKGNIENTIVEGDRIEDFENAIKQNTTLIYLECPST
                     AVFKMQDIKAIVALAKTHNIKTVIDNTWATPLYQRCIEMGIDLEVHSLSKYLNGHSDV
                     VGGCIIGSKKDIEEIRGSELALYGAKLAPFEAFLVIRGLRTLHARLSVHTKNAKEVVE
                     FLDNHSAVTKVYHPLSKYFNQKKLAKKQLLNYTALLSFEIDAKDVNDVKKFVNKLDLF
                     KIGVSWGGHESLVFAPNIAILNEMTLEQAKALNVSPYTIRISLGLENSEDLINDLNDA
                     LSIL"
     gene            complement(65501..66967)
                     /locus_tag="KOU88_000612"
     CDS             complement(65501..66967)
                     /locus_tag="KOU88_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBK3210527.1"
                     /translation="MKREVTIQKQAISIVLFMAVLFCGLLLPMINNKSEYSLPIESIM
                     FISASIISLFIVVTTNKTWEEVFESGLDGVKGALPGLIILLVIGPLIAGFIMSGLMPM
                     LVYYGVKLINPRFVYATALILSALFSSFTGTSWGSAATIGVVMMGVGNAIGANNAIIA
                     GAIVGGAYFGDKMSPLSDTTNIAAIASKVNLYDHVASMLWTTGPATIIALVIYIACGF
                     IFPATNTNLNSPEITRLLADLSGMFNFNIILFIPLLIVLVGSAMKKPAIPVMTIAAFL
                     SLAFAVIFQGFSLADVLIGLNSGFSLDMVTWHEYAKPIEGQAYILGFFQKGGFWELGK
                     LLPISTSILFVVGVLGSIDAMPATVNVIFGWVKSRTAIICSSLLTGIAMIAMTANGIA
                     CSFVTAGIFGDKYDENNIDRRVLSRTTEDTGTLLEVLFPWTPAAIFFTQTLGVNVGEY
                     ALWSIVNWGTPIIAVILAVTGIGTYKNSKDKKQSNKVS"
     gene            complement(67244..68059)
                     /gene="rhaD"
                     /locus_tag="KOU88_000613"
     CDS             complement(67244..68059)
                     /gene="rhaD"
                     /locus_tag="KOU88_000613"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBK3210528.1"
                     /translation="MSIMEMNFIKDFMKITYDAWLKGWHERNGGNITYRLTPEEISGI
                     KEFITEEIEYIPIGVTVENLANEYFLVTGSGKFMRNISINTVQNVGIVKIDEKGENYA
                     IVWGLDKAKPTSEFPSHLMSHSIKKDKTNGLHRVIMHSHTTNLIALTFILPLEGKVFT
                     RELWEMATECPVVFPEGIGIVPWMVPGGIEIAKATQNLMEKHNIVIWAHHGTFCSGET
                     LDLTFGLMDTVEKSAEILVKVISMGGKKQTITGDNFRDLSKNFKVSISEDYLY"
     gene            complement(68070..69326)
                     /gene="rhaA"
                     /locus_tag="KOU88_000614"
     CDS             complement(68070..69326)
                     /gene="rhaA"
                     /locus_tag="KOU88_000614"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBK3210529.1"
                     /translation="MELKQRYEVAKKEYEKWGINVEEVLRVLSKVKISIHCWQGDDVT
                     GFEGNQQRLSGGIASTGNYPGKARNPQELRRDLDKALSLIPGKHKVNLHAIYAETGGS
                     FVDRDELKPEYFENWVKWAKERGLGLDFNPTIFSHPKSSDGLTLSHPDKKIRDFWIKH
                     CIASRKIGEYFGKELGQTCLTNIWIPDGYKDIPSDRLGPRRRLKESLEEILKVEINRE
                     YNLDCVESKVFGLGVESYTVGSNEFYLNFASKNNIISLLDTGHYHPTELVSDKLSSML
                     LFSDKVALHVSRPVRWDSDHVVILDDELKEIAKEIVRNDALDKVIIGLDFFDASINRI
                     AAWVIGTRNMIKALLSAMLMPHEELRKLQDEGDFTKRLAIMEEFKTYPMGDIWNYYCK
                     INNVAVKEDWIEVVKEYELTELLNRK"
     gene            complement(69347..70741)
                     /gene="rhaB"
                     /locus_tag="KOU88_000615"
     CDS             complement(69347..70741)
                     /gene="rhaB"
                     /locus_tag="KOU88_000615"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBK3210530.1"
                     /translation="MRYYLAIDIGASSGRHIISYINNGKLEIEEVYRFKNNLIKKDGH
                     FCWDISKLFSEIKNGIKKCIKINKIPVSVAIDTWAVDFVLLDEKDNILGNCVSYRDNR
                     TDGIMEEAFKIIDKKELYLKTGIQFQKFNTIYQLLAIKNQQPDLLEKAKSFLMIPDYF
                     NFLLTGKKVTEYTNATTTQLVNTTTNNWDEEIINKLGFDKMLFAKIKTPKTILGSLKK
                     ELVEELGCDLEVILPVTHDTGSAFMSTPVKNRSILLSSGTWSLLGVELERPKCKLEAL
                     DYNFTNEGGYEYRYRFLKNIMGLWMIQEARKCYDSKHSFTELVEHARLSEGFKSIVDV
                     NDDRFLNPENMVQEIIKYCIETNQTEPQTVGEVAYCIFNSLAKSYSKSINEIEEIIGE
                     KLETISVFGGGCQNELLNELIAKESGKKVLAGPVEATALGNIVCQLIAKNELNDLEQA
                     RDIIRNSFDIIQYN"
     gene            complement(70948..71919)
                     /locus_tag="KOU88_000616"
     CDS             complement(70948..71919)
                     /locus_tag="KOU88_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3210531.1"
                     /translation="MRQYIHDKLREITEEEKNILEGNYIIDKSIYTDNSQFIIDSNKL
                     LNIDELIHIRKHTRFAQFPKHKHNYIEFNYVYRGKLVQTIDEYKINLKQGELIFLNQH
                     VIHEIEASDEEDIIINFIIKPEFFDYIISLLENDNKIMNFLMTTLYTNYNLGEYIYFK
                     VSEKEEIQDIIEKIIIELYEPSVVNKVKIKLLVGLLLVELVKNSEDVENHAVDNYEKM
                     MIIEILKYIDKDYKKGSLSEIASNLNQGDYKISKLVKKHLGYTFKDLVQEKRLSKACE
                     LLVSTNLSIAEIIENVGYENLTYFYKIFKNKYGITPKEYKKNIKNSQ"
     gene            complement(72043..72324)
                     /locus_tag="KOU88_000617"
     CDS             complement(72043..72324)
                     /locus_tag="KOU88_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210532.1"
                     /translation="MKDETLEDILKQKTQAERYILEYIVTKNVKKLDNKKIVSILHTI
                     LCWEEINGTIVLTDKNILSLDEDIMISKHRRFIDIPKHKHNFIEFHLMS"
     gene            72510..72830
                     /gene="rhaM"
                     /locus_tag="KOU88_000618"
                     /pseudo
     CDS             72510..72830
                     /gene="rhaM"
                     /locus_tag="KOU88_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895446.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
     gene            complement(73499..73639)
                     /locus_tag="KOU88_000619"
     CDS             complement(73499..73639)
                     /locus_tag="KOU88_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210533.1"
                     /translation="MENLMMSIITGVIASYIYDKLKSHSERPTKSGWELNIKFQKSKS
                     SK"
     gene            complement(73899..75059)
                     /locus_tag="KOU88_000620"
     CDS             complement(73899..75059)
                     /locus_tag="KOU88_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp27"
                     /protein_id="HBK3210534.1"
                     /translation="MKLSKILLAIGMSVSLLIASCPTSNALSSINSIKGTNKYETAGL
                     IADKQNYDIAILINSENGLSDGLSASGLSGAKNAPILLTKKDTIPSETLKRLEKVKEV
                     YLIGGKNSIGASVQKILSDKKISINRISGTDRIDTSHKVAKEIGRVSTVKKVILTNAF
                     KGEPDAMSVASIAVRDKSPIVLTDGNTTSFATDGLETYAIGGKVSMSDKLINETKATR
                     IGGVDRYDTNKQIINKFYNGSKEFYIASGTDLVYSLVGSTIAQKTPIVLVGNGSNKSI
                     LKNASKITAIGNIDDVVIKQCLNITNNVGDSNTGIVKDTNSNNTNKPSNEPSSNNPGL
                     TDKSTVYVTPNGKSYHLTKNCSTLKRSKTINKVTLKQAKSQGKIDPCNVCVK"
     gene            complement(75230..75433)
                     /locus_tag="KOU88_000621"
     CDS             complement(75230..75433)
                     /locus_tag="KOU88_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4236 domain-containing protein"
                     /protein_id="HBK3210535.1"
                     /translation="MGFNFRKSINLGGGLKLNLGKKSVGISAGVKGARVSVNSKGRKS
                     ATLSIPGTGISYTKTSTKKRKPK"
     gene            complement(75520..76554)
                     /locus_tag="KOU88_000622"
     CDS             complement(75520..76554)
                     /locus_tag="KOU88_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YHYH domain-containing protein"
                     /protein_id="HBK3210536.1"
                     /translation="MFKKKLIAVAMSITMISVGSFSYAHSGRTDSSGGHRDNKNKSGL
                     GSYHYHCGGYPAHLHNNGGCPYTGGGSSSGTTTSVNNEEKQKRSVGEKGYNQGYEDGY
                     KGNYSSSNYSGDYSDTYESKYSEGYEKGKAKLEEEEKVAKETGYNLGLTGAKSNNTYE
                     KEALKNAYDTGYSTGYNEYKTKKIEEYKAKGIEDSNKDKEKMTFEENIDSEFIDAYNN
                     AYDEIQEQLKNDYTTQGFESAIKGERFDTSTIGNVKYANWFKEGYDNGKVKLPKAKES
                     VYNQGYNEEDFSIPDEMKSIETKLKGVYDEGLEKREEEKSRNATYGVGAGTAAVVAGV
                     VYKKKKRKKI"
     gene            complement(77076..78437)
                     /gene="rlmD"
                     /locus_tag="KOU88_000623"
     CDS             complement(77076..78437)
                     /gene="rlmD"
                     /locus_tag="KOU88_000623"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBK3210537.1"
                     /translation="MSVKKKDVIEFEVDKMEFGGTSLSQVGDRVIHMKGGISGQKVKA
                     GVKKVRSKKAEVKMIELLENSPLETEETCKHFRECGGCTLLSVPYEKQLEIKEKQVMD
                     LFLKQDLFGFQFLGIEGSPENKYYRNKMEYTFGDEVKNGPLTLGLHKKGKHIDIQTVE
                     ECMLVDEDFSKILVSSVEFFNEKKLPYYRTMNHKGYLRHLVVRKGIHTNEIMVNIVTS
                     SQEDFDMYEFKDMLLGIDLKAELVGVLHTINDGLADAVQCDELRVLYGRDYIQEEILG
                     LKFKISPFSFFQTNTKGAEVLYSIARDFIGDYNDKVVFDLYSGTGSIGQVMAGAAKKV
                     YGIEIVEEAVVAANENAKLNGLTNCEFIAGDVAKVVKDLKDKPDLIIVDPPRPGIHKD
                     AIRDICGFGAKEIVYISCNPKSLVVDLVDFKGYGYEIKMVKCMDMFPNTPHCETVVKL
                     IRE"
     gene            complement(78464..79186)
                     /locus_tag="KOU88_000624"
     CDS             complement(78464..79186)
                     /locus_tag="KOU88_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBK3210538.1"
                     /translation="MAKKQRIDKILSNLGYGSRSEIKKYCKQGSVVVNGSEVSNTGTQ
                     VDTENDEILFNGEEVIYREYIYLMMNKPDGYISATTDKYDPTVLDLIDLSYLAFEPFP
                     VGRLDKDTEGLLVLTNDGKLSHRVLSPKKHVPKTYYAKIDGVVTEEDVEAFLEGVVLD
                     DGYKTMPSQLNILKSDDESEIELTIHEGKFHQVKRMFESVGKKVVYLKRLSMGNLKLD
                     ESLELGEYRELTDEEVKLIEER"
     gene            complement(79186..79515)
                     /locus_tag="KOU88_000625"
     CDS             complement(79186..79515)
                     /locus_tag="KOU88_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1904 domain-containing protein"
                     /protein_id="HBK3210539.1"
                     /translation="MPQIKIRGINENDICKISEKMINDLVEAVKCPRDYFEIECIKSV
                     AIRDGKIADVYPFVEVAWFDRGQEVQDIVARIITDSIRNNLDVESMDLAFTVFEKEKY
                     YENGEHF"
     gene            79845..80771
                     /gene="fba"
                     /locus_tag="KOU88_000626"
     CDS             79845..80771
                     /gene="fba"
                     /locus_tag="KOU88_000626"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-1,6-bisphosphate aldolase"
                     /protein_id="HBK3210540.1"
                     /translation="MALITTKEMFKKAYEGGFAIGAFNISDLEQLQGVLKAAKAKNSY
                     VMIQASMSAVKYAGPHTLVEMVKAASDEIGVDVALHLDHGPNMDAIKTCIDAGFSSVM
                     IDGSHFDFEENVRITKEAVEYAHSKGVVVEAELGVLAGTEDDVTSDVHKYTQPAEAVE
                     FVERTGVDSLAIAIGTSHGAFKFKGEAKLRFDILEEIQSKLPGFPIVLHGASAVDQNA
                     VATCNEFGGNIAGAKGVPVDMLRKASSMAVCKINMDTDLRLAMTAAIRKFLAENPKEF
                     DPRKYIGAGRDAIQAVVESKIDDVLGSANSIN"
     gene            complement(80906..82537)
                     /locus_tag="KOU88_000627"
     CDS             complement(80906..82537)
                     /locus_tag="KOU88_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3210541.1"
                     /translation="MDNNLIGLIEHVENPAILCKESGEIIYCNHLIDSIFSFLDIKKP
                     RNINELDSNFDKTEILTDSKKKIAFRELRMTAHIYNMKDNNNENNIVYLFEKSLISDK
                     VIEDIIEHIDEVVVVFNKDGVIEKMNTVSDEILPFKRTEVLGRNITDLVRQGLVEEPI
                     ILNMLKVKKKIYRNIVYPDGKLIAYTAVPRWDSKGKLTGGVLTGRDISRVIKLESQIK
                     YSDISEDTEYISQSKIMDNIKKVVKRAAASDSSIFINGESGVGKEIIARTIYKYSSRR
                     DKPFIAINCGAIPNELLESEFFGYEEGSFTGAKKKGKKGLFEEANGGTIFLDEIGELP
                     MQMQKKLLRVIQENTITRIGGSKPIKIDVRYISATNISHEDLRNNLKFRQDLYYRLSV
                     IPVKIPPLRERKEDIVPLVNYFLKLYNEKYNREVEVSPKVIELLEEYSWPGNIRELKN
                     IIERFVVLSAKNVIGEDEFNMLINLDMIDNETDDLSPIVVNGIMNLNDAYKIVDQIMI
                     SKAINKYGSITKAAEVIGIYPSTIHRKIKSGHIHV"
     gene            complement(83020..84057)
                     /locus_tag="KOU88_000628"
     CDS             complement(83020..84057)
                     /locus_tag="KOU88_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBK3210542.1"
                     /translation="MNDIKDLSSYKNVWIFAEQREGKIAPVVIELLGEGRKLAKEVDA
                     ELCAILLGKDVDGLAKELITFGADKVYVADDALLEKYTTDAYTKVIKDAIDEIKPEIM
                     LFGATHIGRDLAPRIASRVGTGLTADCTKLEIDPEDKKIKQTRPAFGGNIMATIICPN
                     HRPQMSTVRPGVMDKAEKDETRTGEVIALDYKITQDDIRTTVLETVKTKKDLVSLTDA
                     NVIVSGGLGLGGPEGFEMLKKLADKLGGVVGSSRAAVDAGWIDHSHQVGQTGTTVKPN
                     LYIACGISGAIQHLAGMQSSDFIIAINKNPAAPILEIADYGVVGDLHEIVPMLIEKLD
                     SVDDLLEAIKA"
     gene            complement(84076..84861)
                     /locus_tag="KOU88_000629"
     CDS             complement(84076..84861)
                     /locus_tag="KOU88_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012703997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBK3210543.1"
                     /translation="MKILVCVKQVPDTNEVRINKETGTLIRDGVPSILNPDDANALEE
                     ALKIKDEHDDVTITVITMGPPQADFMLRECLAMGADDAILLSDRAFGGADTWATSNTI
                     AAGISKVGDYDIIFAGRQAIDGDTAQVGPQIAEKLDIPQVTYVQDFKIEGKDIIVQRQ
                     LEDGYELIKVSTPVLLTAVKELNTPRYMSVDKIVKAYKHDVKVWTIDDLDVNKEEVGL
                     KASPTKVFRSFTPEPRGKGEILEGKADEIASKIIIGLKQKHII"
     gene            complement(84894..86027)
                     /locus_tag="KOU88_000630"
     CDS             complement(84894..86027)
                     /locus_tag="KOU88_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBK3210544.1"
                     /translation="MLYNKEQELLRKAVRDFVSKELDTLPAEMDKTGVMPKELIKKLA
                     DAKFISSNIPEEYGGGGAGYVSYAIVMEEIARRCASTATFVTAGSSLASLPILYNGTE
                     EQKQKYLKGIATGELIGAFGLTEPGAGSDAGGQQTTAELVGDHYILNGRKTFITNGPF
                     CDVAIVIAVTDRSKGLRGTSAFIVESKWDGFSTGAHEDKMGIRGTETSDLIFENVKVP
                     KENLLGKEGQGFKIAMGTLEVGRIGVAALALGIAQGALDEAVKYTKQRVQFGKPIAKF
                     QNTQFTIADMETKVCAARGLVYDAAQKRDAGMRVAQESAMAKYYASEIANEVAYKALQ
                     LHGGYGFIKDYEIERMYRDARIVSIYEGTSEVQKMVISSNVLK"
     gene            complement(86075..87202)
                     /gene="hadC"
                     /locus_tag="KOU88_000631"
     CDS             complement(86075..87202)
                     /gene="hadC"
                     /locus_tag="KOU88_000631"
                     /EC_number="4.2.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     beta"
                     /protein_id="HBK3210545.1"
                     /translation="MEAILSKMKEVVENPNAAVKKYKSETGKKAIGCFPVYCPEEIIH
                     AAGMLPVGIWGGQTELDLAKQYFPAFACSIMQSCLEYGLKGAYDELSGVIIPGMCDTL
                     ICLGQNWKSAVPHIKYISLVHPQNRKLEAGVKYLISEYKGVKRELEEICGYEIEEAKI
                     HESIEVYNEHRKTMRDFVEVAYKHSNTIKPSIRSLVIKSGFFMRKEEHTELVKDLIAK
                     LNAMPEEVCSGKKVLLTGILADSKDILDILEDNNISVVADDLAQETRQFRTDVPAGDD
                     ALERLARQWSNIEGCSLAYDPKKKRGSLIVDEVKKKDIDGVIFCMMKFCDPEEYDYPL
                     VRKDIEDSGIPTLYVEIDQQTQNNEQARTRIQTFAEMMSLA"
     gene            complement(87202..88428)
                     /gene="hadB"
                     /locus_tag="KOU88_000632"
     CDS             complement(87202..88428)
                     /gene="hadB"
                     /locus_tag="KOU88_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(R)-2-hydroxyisocaproyl-CoA dehydratase subunit
                     HadB"
                     /protein_id="HBK3210546.1"
                     /translation="MSEKKEARVVINDLLAEQYANAFKAKEEGRPVGWSTSVFPQELA
                     EVFDLNVLYPENQAAGVAAKKGSLELCEIAESKGYSIDLCAYARTNFGLLENGGCEAL
                     DMPAPDFLLCCNNICNQVIKWYENISRELDIPLIMIDTTFNNEDEVTQSRIDYIKAQF
                     EEAIKQLEIISGKKFDPKKFEEVMKISAENGRLWKYSMSLPADSSPSPMNGFDLFTYM
                     AVIVCARGKKETTEAFKLLIEELEDNMKTGKSSFRGEEKYRIMMEGIPCWPYIGYKMK
                     TLAKFGVNMTGSVYPHAWALQYEVNDLDGMAVAYSTMFNNVNLDRMTKYRVDSLVEGK
                     CDGAFYHMNRSCKLMSLIQYEMQRRAAEETGLPYAGFDGDQADPRAFTNAQFETRIQG
                     LVEVMEERKKLNRGEI"
     gene            complement(88443..89243)
                     /gene="hadI"
                     /locus_tag="KOU88_000633"
     CDS             complement(88443..89243)
                     /gene="hadI"
                     /locus_tag="KOU88_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyisocaproyl-CoA dehydratase activator
                     HadI"
                     /protein_id="HBK3210547.1"
                     /translation="MYTMGLDIGSTASKGVILKNGEDIVASETISSGTGTTGPSRVLE
                     KLYGKTGLAREDIKKVVVTGYGRMNYSDADKQISELSCHARGVNFIIPETRTIIDIGG
                     QDAKVLKLDNNGRLLNFLMNDKCAAGTGRFLDVMAKIIEVDVSELGSISMNSQNEVSI
                     SSTCTVFAESEVISHLSENAKIEDIVAGIHTSVAKRVSSLVKRIGVQRNVVMVGGVAR
                     NSGIVRAMAREINTEIIVPDIPQLTGALGAALYAFDEAKESQKEVKNI"
     gene            complement(89282..90481)
                     /gene="hadA"
                     /locus_tag="KOU88_000634"
     CDS             complement(89282..90481)
                     /gene="hadA"
                     /locus_tag="KOU88_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocaprenoyl-CoA:2-hydroxyisocaproate
                     CoA-transferase HadA"
                     /protein_id="HBK3210548.1"
                     /translation="MLLEGVKVVELSSFIAAPCCAKMLGDWGAEVIKIEPIEGDGIRV
                     MGGTFKSPASDDENPMFELENGNKKGVSINVKSKEGVEILHKLLSEADIFVTNVRVQA
                     LEKMGIAYDQIKDKYPGLIFSQILGYGEKGPLKDKPGFDYTAYFARGGVSQSVMEKGT
                     SPANTAAGFGDHYAGLALAAGSLAALHKKAQTGKGERVTVSLFHTAIYGMGTMITTAQ
                     YGNEMPLSRENPNSPLMTTYKCKDGRWIQLALIQYNKWLGKFCKVINREYILEDDRYN
                     NIDSMVNHVEDLVKIVGEAMLEKTLDEWSALLEEADLPFEKIQSCEDLLDDEQAWAND
                     FLFKKTYDSGNTGVLVNTPVMFRNEGIKEYTPAPKVGQHTVEVLKSLGYDEEKINNFK
                     DSKVVRY"
     gene            91158..92156
                     /locus_tag="KOU88_000635"
     CDS             91158..92156
                     /locus_tag="KOU88_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-2-hydroxyacid dehydrogenase"
                     /protein_id="HBK3210549.1"
                     /translation="MKILVFGARDYEEPVIKKWSEEHKDVQVDIYPENMTEENVVKAK
                     GYDGISIQQTNYIDNPYIYETLKDAGVKVIASRTAGVDMIHFDLVNENGLIVTNVPSY
                     SPNAIAELAVTQAMNLLRKTPLVKKKVCEGDYRWIAELLGTEVRSITVGVIGTGKIGA
                     TSAKLFKGLGANVIAFDQYPNSDLNDILTYKDSLEDLLKEADLITLHTPLLEGTKHMI
                     NKDTLAIMKDGAYIVNTGRGGLINTGDLIEALESGKIRAAALDTFETEGLFLNKKMNP
                     GELTDPEINKLLSMEQVIFTHHLGFFTSTAIENIVYSSLSSAVEVIKTGTATNRVN"
     gene            92518..93045
                     /locus_tag="KOU88_000636"
     CDS             92518..93045
                     /locus_tag="KOU88_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04002 family protein"
                     /protein_id="HBK3210550.1"
                     /translation="MEKMNKVTSKKTTYIVTSALFASIICLTIAYILHIPVGGNNGYV
                     HIGDAFIYLAATILPTNYAIAASAIGAGLADLSTGAAIWVIPTIIIKPILVLFFTSKS
                     DKIINKRNIVASVVAGIVGLVLYMFAEGIIIGSFTSAFVMSLLGLLQPIGSFIVFIIL
                     GMALDKLDFKKRYFN"
     gene            93072..93668
                     /locus_tag="KOU88_000637"
     CDS             93072..93668
                     /locus_tag="KOU88_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04100 family radical SAM protein"
                     /protein_id="HBK3210551.1"
                     /translation="MNILYTIENSIYVNITNTCPCSCVFCIRNEKDEVANSGSLWLEH
                     EPSVDEVKEAFNKYNLDDYDEIVFCGYGEPLMRINELIEVAKFIKEKSSIKIRINTNG
                     LSDLIHNKKTAILLKNVIDAVSISLNAPNKEAYNRVTQPKFGEKSFDYMLDFAKDCKK
                     YIKEVAFSVVDEISPEEIEESKQLAKKLDIPLRVRHKN"
     gene            complement(93747..95330)
                     /gene="asnB"
                     /locus_tag="KOU88_000638"
     CDS             complement(93747..95330)
                     /gene="asnB"
                     /locus_tag="KOU88_000638"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBK3210552.1"
                     /translation="MINLEEKYLTRKDTYMIKILEYNGHIRNWKVLCEELGIDSSLCR
                     DERERAILVEAYKTWGYDMANHMHGMFAFALWDTVEKKLFCLRDQFGVKPFYYYETEN
                     GKLLYGSSIRKIMEQPGFVKELNEDMLQIYMSFTYVAGENTFFRGVKKLMPGHYLVYQ
                     NKTVCIGRYWKPEFHPDHSKSIEEWTDEIHTTLQKIMPEVKSENETAELFLSGGVDSS
                     YILAMSDIEKTGSCGYEEERFDESKLAQQTANILGCKNSRYIITPEEYFASVPYVMYH
                     MEQPTGDASAIVFAIGCKAAAENTNICYSGEGADEFFGGYNIYHKAECYGENLKTFYI
                     GNTNIMNEGEKRKILKKYNPDVLPIEVVKGIYEETEELDTLTNMSNVDIQIWLEGDIY
                     FNIDKMSTAVGLEVRMPLTDTRIFDIASRIPSEYKVKGKENKIAFRTAASKTLPEEIA
                     FRNKLGFIVPIRIWMADDQYNKDIRDKFNSEIADKFFNIDEINEIFNDYISGNSDNWR
                     KIWMIYTFLVWYEIYFVKC"
     gene            complement(95932..96768)
                     /locus_tag="KOU88_000639"
     CDS             complement(95932..96768)
                     /locus_tag="KOU88_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK3210553.1"
                     /translation="MNYIIKKVLNSSVVLVHDTKDNEFILLGKGIGYGKKTGEYICGS
                     NDNQMFVPVENTKSKQFLELMDDIPVDILKITQEIIVEAEKLLNSSFNKNLYLILADH
                     FNFAIERMRKGIKITNRVFWEIKNYYPNEFKVGMVAIYMVEERLGIQLPEEEAANIAF
                     HFANAMASDGNSYDTIKYAKVIGEIINIFVFSLNRTLDKKSMHYMRFITHIKFFVERF
                     FSDSMLSSGDDLLFNQMKRSNPKEMLIALKVRDFLEKKYGKKLTNEEIAFLVVHIARV
                     KQ"
     gene            complement(96792..98258)
                     /locus_tag="KOU88_000640"
     CDS             complement(96792..98258)
                     /locus_tag="KOU88_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBK3210554.1"
                     /translation="MRKFPEGFLWGGATAANQFEGGWNLGGKGWSVSDVAKAHFDADV
                     KDYKSNNEITTKDIEEGLAHPEDEVNYPKRHGSDFYHHYKEDIALMAEMGFKTYRMSI
                     AWSRIFPNGDDKEPNEEGLQFYDDVFDELISYGIEPLVTMSHYEPPLNIVLNYDGWYS
                     RQVINMFVRYVETICERYKNKVKYWLTFNEVDSMIRHPYTTGGLVRDRFKDKNFEEVI
                     FQAMHHQFVASALATKICHEIIPNSKVGCMLTKLTYYPYTCRPEDVLATQQKMRSIYA
                     YSDTQVFGEYPVYLLSYFKNNNIQIVKEEHDDEIMKKYPVDFISFSYYMSSCEAADTT
                     GLDITPGNTLLAVKNPYLEMSEWGWQIDSIGLRISLIELYDRYRKPLFIVENGLGAKD
                     ILTEDKKVHDQYRINYLKEHFKCMLDAIIEDGVELWGYTSWGCIDLVSESTKQMSKRY
                     GYIYVDADDYGKGTYNRYKKDSFYWYKKVIENNSIDFK"
     gene            complement(98261..100123)
                     /locus_tag="KOU88_000641"
     CDS             complement(98261..100123)
                     /locus_tag="KOU88_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3210555.1"
                     /translation="MNYKKTAIDIIEQVGGSKNILALEHCSTRLRFKLIDRSKVNQDA
                     LKKVQGVMSIVNGAQFQVVIGNSVVDVYDEILKVCPLDTNDSTVKTEEKINLGKRFIE
                     FIINIFQPLIFAIAGAGILKSLLMLLAMFNILKSDSTIYTLLVAISDATFYFLPIMVA
                     VTTANVLKCNRLVAIAAVGYLLLPATTTALSEGVELFGFTIPNIAYNAQVFPAILCVS
                     FLATMEKIFNKYSPKPIRTFFVPMMSLAITVPITLTILGPLGYNVGTIFTTIILFLYN
                     KMGFLVVGLLAAFLPFMVATGMHKALIPYSINTIGKLGYEALYMTSSLAHNISESGAC
                     FAVALRTKDETLKQTALSAGISALMGITEPALYGITLQHKRAMLGVVFSSAISGTFLG
                     LFAVKGFVIVGPGLASMSMFIDPNNGNNLIFASIGFVIAILGSFIITLIIWKEDTNTV
                     ESSIGDVVEEELEEEKEVNILVTPVEGKVIDLSKVNDELFASKTLGDGVAIIPTNGNL
                     YAPCDSEVVMLFETKHAIGLRTKNGAEILIHIGINTVSMNGDGFKTFVKTGDNVKEGD
                     LLIQFDLDKISHANLDSTVMIVNNNGADYAYKVLNQSYGNVKKGSILFDVKGGI"
     gene            complement(100370..101233)
                     /locus_tag="KOU88_000642"
     CDS             complement(100370..101233)
                     /locus_tag="KOU88_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBK3210556.1"
                     /translation="MILSYFALLIRVVLLAFERVVVRLLGDEEGDIYKNIASSFLFFF
                     IGGVCLLPFSIMDRVSDWSFLIPCYISSLVYSIGSVAYVTSLATGEVSLVTPINSLNS
                     LFLLLLSVIFLGEGLSLAKVAGIIIMIGGVFILKKVSSFLKNVSVIFNNLPCRLMFLY
                     IFLQSVGRVLDKAFFVQVSPILYSTILYFFVGLNLFIFLAFKKKQKIICEIFTNKKGL
                     SILSGAINGYSYLALLIALNNLELSIAEPFSQVSMIITLILAHFIFKENIKEKIPGSI
                     LILIGGWLLLL"
     gene            complement(101288..102220)
                     /locus_tag="KOU88_000643"
     CDS             complement(101288..102220)
                     /locus_tag="KOU88_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacyl-tRNA deacylase"
                     /protein_id="HBK3210557.1"
                     /translation="MNNKKAVFFFCSDLKKDPVASNVIKCCEEIMDLNQTDIVIDDNF
                     VLEFKDKNNNLFHFVKTKDVISHNYKYYLPILNRHFRDYDFAGVVNWHEGENAPEHIL
                     TAHTIGDVPTGEFGNSNPRYFKNLINAIEDIKNENLLDEFTTLTEATHWSGTTYGEES
                     KLITEYSVPMLDIEIGSSSDSFNNSIAIQVLAKSLIRVFDCDEPLKTLLCVGGVHFEK
                     SFSDIIKNKEYNISIGHVLPNQWIVSGMYDDESGFEKLEKCINSIEGGIDCIVFHDKL
                     KGTYKEQCRKLGEKLNVPVFKHKILKNPKDLPIW"
     gene            complement(102306..102857)
                     /locus_tag="KOU88_000644"
     CDS             complement(102306..102857)
                     /locus_tag="KOU88_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3210558.1"
                     /translation="MQSLNEIIAENLKKIRKEKHLSLDKIAQLSGVSKSMLSQIEKCE
                     VNPTISTLKKITNGLKISFTSLMERQESDIELIQKSDIDHFIEDNGKYISYPIFPFDS
                     KRRFEIFMIEIEEGGNLDSNAELPGTQEFITVFSGEVTIKINGEDYIVSSGNSIRFKA
                     DVSHIYRNSGKGIAKMSMVVYYI"
     gene            complement(103086..103577)
                     /locus_tag="KOU88_000645"
     CDS             complement(103086..103577)
                     /locus_tag="KOU88_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210559.1"
                     /translation="MIDLKIENRKGKIHVKSSEIKDILELRPDFEYVQDISNTINQEN
                     ILVFDCQLTGNSFDMDDLDIEEILEELGEEIDESYFSVLFEDVRAYLKDATDEIEADL
                     QDNYLFDNLRCYFDIYNINQEFTDFKFVFLVSFKDIKISSLANLAKIVSKRQLIGASK
                     FYS"
     gene            complement(103605..104165)
                     /locus_tag="KOU88_000646"
     CDS             complement(103605..104165)
                     /locus_tag="KOU88_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBK3210560.1"
                     /translation="MNKLNICIDIDGTITSPYHFLPYLNDIFNKNITEAECITHNWEE
                     LYGSGIRDVYAEFNNKYIHSYDEAKIVEGATEVISTLSKGHNLSFVTARHECLTDVTK
                     NWLSRQGFSDIDVYLLGSDYKVEKARELSCDIFIEDNPLNSVQLADDGVKVILLDTNY
                     NKDVKHQNIVRVSNWIDIEKIIKQGI"
     gene            complement(104317..105474)
                     /locus_tag="KOU88_000647"
     CDS             complement(104317..105474)
                     /locus_tag="KOU88_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBK3210561.1"
                     /translation="MNKQSIGKLNMFFMGITQRNLDNRDFFIELEVIFKSGRKEFKGI
                     AIEEDNKYKFNFKGKSDLYTFNELLKNISKEAENYDGLVFKYVERGTIVVIEGDNKKV
                     NVKYLDNKEEVPKIDEFTASQIKNRDYYVKVGQANALLKEIGVLTKDGKIKNDKIRKY
                     NQIDHFVELIDSILKEIKDKDCITILDCACGKSYLSFVLNFYIKEVLKKNCYFIGIDY
                     SDVVIEASKNMAKNLGYKNMSFIKEDLTNYTPNRDVDLVISLHACDTATDMAIGLGIR
                     AKSEAIVVVPCCHKELLGQYRYEAMEPILKHGVFKARFADLITDGLRTLLLEGNGYDT
                     SVVEYISPLDTPKNLMIRAIKTKTNNDKALKEYKELKSQFGVEPTLEKLIY"
     gene            complement(105511..106452)
                     /locus_tag="KOU88_000648"
     CDS             complement(105511..106452)
                     /locus_tag="KOU88_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210562.1"
                     /translation="MRWILVFIFLYLIPLVVIFRNYKNFKRSCIYSSIYVVLATTIMI
                     SNIYMSGLNKIKESMYYHNYISDETYDEKYVSNFKEKESTDLKQDNKKNEEISNNKNL
                     NNKQDRNIQNKESNEEGSNDIKEKNNSDSNVSVNNKSEKQEDNTKENNKYTSKEKNSE
                     DIKKIDMESIGIFKKEIYNIERAALVPMRECIPYTKDIAKNITKLSSIKKDVTNARNK
                     CKEVVKEYENMQIPELSKEKYTETLSNARDDVKKAYELREKSMESALKLINTKSPKYI
                     GKITEYLDLSDKQIESFKNRLNDLKEEINNSETNNIN"
     gene            complement(106539..107231)
                     /locus_tag="KOU88_000649"
     CDS             complement(106539..107231)
                     /locus_tag="KOU88_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK3210563.1"
                     /translation="MSLYAIGDLHFSTSVNKPMNIFGSNWDGHEKKIIDNWKEVVKEE
                     DMVLVLGDTSWGINLSEAKKDLDIISKLPGQKILIKGNHDYWWTTVTSLNKLYEDMRF
                     IQTNFYEYKDYAICGGRGWICPNDVKFDETDEKVYKREEHRLRLSLESARKSGHSKII
                     VITHYPPTNDKLEESLFTKLFEEYNVEKVIYGHLHGKESFKMGLKGIRNGVEYTLASC
                     DYTEFNLIKVHD"
     gene            complement(107340..108152)
                     /locus_tag="KOU88_000650"
     CDS             complement(107340..108152)
                     /locus_tag="KOU88_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBK3210564.1"
                     /translation="MEYEKWNEILAPYEHAVEELKIKFKNIRKEYLAKGEYSPIEFVT
                     GRTKKISSIISKLKRINAKDIETEIDDIAGIRIMCQFVEDIYAIVDLIKVRNDMTIIG
                     EKDYITNYKDSGYRSYHVIIKYPINSIAGSKEIICEIQIRTLAMNFWATIEHSLKYKY
                     DHYIPETLAERLRRASDAAFLLDQEMSEIREDIMKAQAMYQMKSIAIRDTLNRIQELY
                     DLGDTHKAMQYQRKLDRTETDKNITEILELKQEIDILLEQYKDTKVDDKVVQ"
     gene            complement(108203..109114)
                     /locus_tag="KOU88_000651"
     CDS             complement(108203..109114)
                     /locus_tag="KOU88_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3210565.1"
                     /translation="MNLTKVKGNTFFIKGGTNTGIYVFEDNTALMIDPGLCGSRPRRV
                     NKVLDENNIQVRYIINTHGHDDHYGACNQFKEYYKDVCIMSSEYDKLYIENPELFSKY
                     IVGGKSNVFMDNILKNKMLDDIKIDKSIEAGKIELNNEMFDIIEFQGHTPGSIAVLTK
                     DNVIFVGDLLIGDEILSKYDFLFLYDIQEQINSLEKLKNIDFEYLVLGHGKQVISKED
                     SYKLIEKHLNALKKYLYQIRELLVEPKSLEILLKNIINNNNLSNNYKEYHFFKSSLVS
                     VISYLVDLEEIGYILENGELLYYTKTK"
     gene            complement(109173..109904)
                     /locus_tag="KOU88_000652"
     CDS             complement(109173..109904)
                     /locus_tag="KOU88_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBK3210566.1"
                     /translation="MTSIKNKDILNCIDYSIKNKLFDKLNDVYKSLPVGNCSGCGNCC
                     MESVGINLIEFLNIFCYLEDRVDLKKSCISKILDYYFEEYTRKNPCPFKDTNNRCLIY
                     EVRPLNCRMFGHWKKEDYNKNLDNVIEKNNNYRELMKKQYGFEINDEVVNYRIDYCDR
                     FIPNKDYLSKSKRLSFFDELMILDSNIYSSGNIDIDFRDRGIVEYFIESLLYRNLAYN
                     VKIRISKEYKIRKRTIDRIKRIVLV"
     gene            109993..110244
                     /locus_tag="KOU88_000653"
     CDS             109993..110244
                     /locus_tag="KOU88_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210567.1"
                     /translation="MNRYTKIINMMGSYYTKDFEKEKKNVIKVREVKEDTVRKFFLQG
                     DCEVLVVFEDTGKEILIDDFSPEEDIKKYLGAKFINKKR"
     gene            110477..110896
                     /locus_tag="KOU88_000654"
     CDS             110477..110896
                     /locus_tag="KOU88_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210568.1"
                     /translation="MQIYFRVKAVGKRKPMLELTPFDVPDNINCLKEAISEIVSKNVL
                     EYNEKIPEKSIINFLTNEEIESQADIGKVGFGSIYNENKQSVEKAIEVALQAFEDGIY
                     KVLINEDVIEKLDSSINLKSGDIFTFIRLTLLAGRMF"
     gene            110921..115978
                     /locus_tag="KOU88_000655"
     CDS             110921..115978
                     /locus_tag="KOU88_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBK3210569.1"
                     /translation="MLERTRVEKNPKIIENFKNNFTKSSSKQYYDLAKSLWDCIENSS
                     YYYREPEDKFLNMIKKYYNCHYYEIKNMDELLSGPLKNALELIFTSEQVEELCQLIKR
                     KMDYTYSGGYYRKGYRSNKLVDYFRGIIRFISNYVDLIYYDFSVIDYLTLPNKVLYYD
                     SIMSDKIALEIDKGNQKVISALEEVIFGENQTALLTRQMIIGIMKSHSDKCYEMLSKL
                     LLAAKQQEGLRQQIVESLDEGTISASIYMLKTILDNNLERFSSVIRALDTWTGLGFSD
                     QKPGIIRKCLELSYKSLTDEKFRIESINSNDNLEIYFALWATATYNIYDSYSLIENLL
                     SCQEKYKKLVALYFLSHTESTYFKHSIASKNIKGDDLEILAWVITNFYVEGSVGYYYS
                     WQNRETNFDLSNTPIDKDFDARKEQFESLKHTLEILNSKTKSFSGSVFPWTWIEISSH
                     EILKCMMTLTAYDMNAQFIDVLMENCHLMSSDLRASLIVNFVNEPKTDRQREFLLECL
                     SDKSVSNRETVLSLLRKLELTDVELDKITNLLSLKTSSIRQTVIKILLEQDDSNLENI
                     ASSLIKSSNSQKCLGGLEIVNLLKDNTARQELYNKLVLLIEDIDKSKKNTSQVQILID
                     NLLGKAKNDYCKENGFGIYNPENKVQIPEQFDFKDDSNSSSKLNKIISNISLSTREDS
                     VSVATKKEAKKILDTDINKIIKVYEKFDELITENADYEYEVERWSGNVDKVLLGYSTY
                     NLTPIKYKVSNDTLDNYPLAELWRETSKKLDLDYKLILDILFYSISTCGYNETEKSWF
                     SSIYSNVLDSKKQNKIYTKLEKLKFNGLTRKLLRVLLNEFDHKEIFNYCLEIYYKLRN
                     LLTIEQCKKQRVEFTKNYYRQNEYCPALNAPILNYWLDKAHSFIYDDISFTKFFYTTF
                     SNYQLLEYKFPFYTSINVFARAHELGLMTEEQVNREMISGYNASNIIRTLTNPRWAGD
                     TLEKYPWLKDNLKTVTNRIIEIESRRGDMPTEVSNLANNIQYFEGINYFVNILVALGK
                     ETFQRGYSYGSNYSKKDVLSSLLKNCYPTKEDDSKKLKSLLKNTDITELRLIESAMYA
                     PQWVNIIEKYLNWKGLKSTIWYFHAHINEGFSAQKESEVALFSPISPRSFIDGAFDVD
                     WFLDSYKTIGEERFNILYKSAKYITSGGNSHRRAQLYADATLGKLDKDMLMKEIETNR
                     NQDKLRSFSLLPMKKGDLKEATFRYEFIQKFAKESKQFGAQRRESESKACTIALENLA
                     RSAGFGDVNRMMWALETEKLNEVAHLFKPKDIDGTSIWIDVDENGKASTKVQKGNKSL
                     KSIPKAIAKHPYVLELKSVQKDLKSQYSRAKQSLEQAMKNEIVFTVKEIANIYKNPVI
                     CPLIKNLVWVCDDNIGYVYNDKSKFFICNIKGETYKLTAKNKLKLAHPVHLFESGKWS
                     EFQHDLFSKQIVQPFKQVFREYYRINSDELSEKTISRRYAGHQIQPKKTVALLRNQLW
                     TVDYEEGLQKVFYKENIVAKMFALADWFSPADIEPPTIETVEFFDRKTYKSLELASIP
                     PILFSEVMRDIDLVVSVAHAGGVDPETSHSTVEMRIAIAKELLLLLKINNVNFEGSHA
                     LIAGNLGEYSVHMGSGIVHKKGMGALNILPIHSQSRGKIFLPFADEDPKTAEIMSKIL
                     LLAEDSKIKDPSILSNL"
     gene            complement(116163..116900)
                     /locus_tag="KOU88_000656"
     CDS             complement(116163..116900)
                     /locus_tag="KOU88_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210570.1"
                     /translation="MIKVLICDDDKIVRDDIANIAKESGYVDYVKKVKDGIEAIEFIK
                     NEKIDLLIIDIDMPYKNGIDSAEEILSIDKDIHIVFVTGFADYSLESFKVHPIDFVVK
                     PFKKEKILDSINIAIDHINSHKIANNNFIEDTLFVYKIRKQIHMINFDDIVMFEKNSR
                     AINLHTKDEDIIKFYENFDDLKKRLPPNFFMTHRQYIVNLRFIHKVIPINKSSLEIRF
                     INFQENAILNKSLEKDFLYRFYRVKRF"
     gene            complement(116919..117854)
                     /locus_tag="KOU88_000657"
     CDS             complement(116919..117854)
                     /locus_tag="KOU88_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK3210571.1"
                     /translation="MDNNFVFPIVILTLFIFSNLIMNKYKFYKELDILKRGILTFFIS
                     CFALILFMEGTKYIQLRLGYSFLLEGVLNIILFLVLIILSFYTGFKVIRLINNNNEQE
                     YKLQKLDSKINHKDNIIIKLRSQKHDYLKHLQVVYSLLNTGLDEDAKEYIMNISNSFK
                     SKNSRYGKVSYLDAIASLKYEECLEKDISFDVYIQDFMDNLEIEPNDMSSVLLNIIDN
                     AIESLSTIKKEKKYIRLHAYEDEFQYIIAIKNNGPKIHNVESIFWNGFSTKEGQDRGY
                     GLHLVKNILDKYDYSILVNSDDFLTEFVILIPKYY"
     gene            118062..120638
                     /locus_tag="KOU88_000658"
                     /pseudo
     CDS             118062..120638
                     /locus_tag="KOU88_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434823.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
     gene            120650..121321
                     /locus_tag="KOU88_000659"
     CDS             120650..121321
                     /locus_tag="KOU88_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210572.1"
                     /translation="MPILETINLGKIYGKKETSVHALKNANLKINKGEFVAIIGPSGS
                     GKSTFLHLVGGLERPSNGTIKVDGKDICCLSDKELARYRRQKVGFVFQQYNLIPVLNV
                     KENIELPLKLDNKKIDKEYIDDLINLLGLNERKNHLPNQLSGGQQQRVAIARALSAKP
                     SIILADEPTGNLDSKTTEEVMDLLKSSIKKYNQTLIIITHNENIARKADRIISIIDGE
                     LKLTL"
     gene            121348..121689
                     /locus_tag="KOU88_000660"
     CDS             121348..121689
                     /locus_tag="KOU88_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210573.1"
                     /translation="MLLILGNLNLNLDFDYRIIREENDDVDIFIDINYRSLDIDTDGS
                     NLFNSRIQFPFVRALILRLNKNNQCMTIHLLRDIDLFSAFANFEVDYTDSIINIKNQN
                     EKVILNKSIKK"
     gene            complement(122049..124691)
                     /gene="adhE"
                     /locus_tag="KOU88_000661"
                     /gene_synonym="adhC"
     CDS             complement(122049..124691)
                     /gene="adhE"
                     /locus_tag="KOU88_000661"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBK3210574.1"
                     /translation="MEKKEKVVEKSNVEVCSPEIVNSVETLRMRLEEIRLAQKEFATF
                     TQEQVDKIFLAASTAANQQRIPLAKMAVEETGMGIVEDKVIKNHFASEYIYNAYKDTK
                     TCGVIEKDEAFGFTRIAEPVGVLSAVIPTTNPTSTAIFKSLIALKTRNGIIFSPHPRA
                     KNCTIEAARVVHDAAVKAGAPKGLIGWVDVPSIELTNVVMAEADLILATGGPGMVKSA
                     YSSGKPAVGVGPGNVPAIIDESADIKMAVSSILVSKSFDNGMICASEQAVIVPEKIYE
                     EVKKEFKYRGAHFLNKEETEKVGKVVIIDGSLNARIVGQPAHVIAKMADVEVPKTARI
                     IIGEVESVELNEPFAHEKLSPVLAMYKSKSFEDAVAKAEKLVADGGYGHTSSLYADSI
                     NHPERVEKFVNAMKTCRVLVNTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVSENVG
                     VKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVAAREFKDVMDKKKAFIVTDSFLY
                     NNGYTKKLTDLLDEMGIKHTTFFDVAPDPTLACAREGAKAMADFQPDLIIAVGGGSAM
                     DAGKIMWVMYEHPEVDFQDLAMRFMDIRKRVYVFPKMGEKAYFAAIPTSAGTGSEVTP
                     FAVITDQDSGVKYPLADYELMPNMAIIDADMMMEMPPRLTAASGVDALTHALEAYVSM
                     LRTEPADGLALQAGKIIFEYLPRAYKNGKNDKEAREKMAMASTMAGMSFANAFLGICH
                     SLAHKLGAFHHVQHGVANALLINEVIKFNCAEAPNKMGAFSQYRYPDCIQRYAEFASF
                     AGIKGSTDQEKVDNLIKAIDELKAKVGLPKTIKEAGVEESKFLERLDAMVEQAFDDQC
                     TGANPRYPLMSELKEIYLKVYYGK"
     gene            125569..127167
                     /locus_tag="KOU88_000662"
     CDS             125569..127167
                     /locus_tag="KOU88_000662"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative manganese-dependent inorganic
                     diphosphatase"
                     /protein_id="HBK3210575.1"
                     /translation="MSLLVFGHKNPDTDSICSAISLAHLKNKLGIKATAYALGDIRKE
                     AKYALDYFKVDAPEILDNVRIQVRDLNYDKVVPLTPTSSILEAYNLMDEKNVKTLPVT
                     YDDGTFAGIITMKEIAKNLLHQHFTTIHTSLSNICKNLNGTILVDCGEDIKGRVVTLS
                     FGMETLIETLKEGDIAIVGDRYDSIEYAIDTKVKLLILTNHTEISKDLLALAKINGVS
                     VVSVESDNYKTSNVINQCSFLDSIEATENLITFKEDDYMDEIKEIMLETNFRSYPILD
                     DDNKFLGLVSKGHLLNPSKKNVVLVDHNEYAQSADGIEQANIVEIIDHHKLGGISTDV
                     PMSFRVMPVGCNSTIIYQMYKENNVEIPYEIAGLLLSAILSDTLLFKSPTTTDIDKKA
                     CEELSKIAKVDMEKYAMDMFKCGTSLDEYTIEEIVNMDFKEFNMSGHRVGIGQVFTLD
                     IDSIFAKKDEFLSYINSTDYDKLILSVTDIIKEGSYLIYKAEDSLIANAFGVEGVQGT
                     FAPGVVSRKKQLVPNLTTAIKNFK"
     gene            complement(127402..>128518)
                     /locus_tag="KOU88_000663"
     CDS             complement(127402..>128518)
                     /locus_tag="KOU88_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-like protein"
                     /protein_id="HBK3210576.1"
                     /translation="GPTGVTGPTGVTGSIGPTGEIGPTGATGPTGATGPTGPTGVTGS
                     IGPTGATGPTGNTGVTGEIGPTGVTGPTGATGPTGATGSIGPTGVTGPTGATGVTGEI
                     GPTGPTGVTGPTGATGSIGPTGVTGPTGATGVTGEIGPTGPTGVTGSIGPMGAIGPTG
                     PTGVTGSIGPMGVTGPTGEIGPTGATGPTGNTGATGSIGPTGVTGPTGATGSIGPTGP
                     TGATGNSSQPVANFLVNAPSPQTLNNGDAITGWQTIIGNSSSITVDANGTFTVQENGV
                     YYISVSVALQPGSSSINQYSFAILFPILGGKDLAGLTTEPGGGGVLSGYFAGFLFGGT
                     TFTINNFSSTTVGIRNGQSAGTAATLTIFRIADTVMT"
BASE COUNT        42725 a        21752 c        15228 g        48813 t
ORIGIN      
        1 ttttaccact tgatgtgtgt gtcactgtaa atactaatgt tacttttgtt tctgtatttg
       61 gaggtattat tgttccatct ttcgctataa cactttcatt tgttgatgat tttatcttta
      121 ttgtgtatcc acttgctact gttggcatag ttagtgttgt tgcatcttgt gttggctgag
      181 ttacacttgt tattttatcc gcctcagctt gtacttctgc ttgtatttcc ccatctgttg
      241 atttggctgg tactactaca tctatttctc ctgtatctgc tgttttacca cttgattctt
      301 gtgttactgt aaataccaat gttactgttt cctctgtatt tggaggtatt attgttccat
      361 cttcctttat aacaccctta ttgcttgatg tttttattgc tatagtatat ccacttgata
      421 ctgatggcat agttaattta gttgcatctt ttgctggtgc aggaacgctt gttatttttg
      481 ccacttcatt gtctaatgct gcttgtaatt cttcatctgt tgatttagct ggtactgtta
      541 cagataattc ttttgtatct gctgttttac cacttgatgt atgtgttacc gtaaatacta
      601 attttactgt tgttgctgta tttggaggta ttattgttcc atcttttttt ataacactct
      661 cattacttga tgtttttatt gctatagtat atccacttga tactgatggc atagttaatc
      721 tagttgcatc ttttgctggt gtaggcacgc ttgttatttt tgctgcttca ttatttactg
      781 atgtttgatt agaagaactt cctcctgaag atgagcctcc tccatgtgaa gaacctccac
      841 ttgatgaact tcctcctgaa gagttagaac ttggactatt tccacttatt gttggagaat
      901 tatctccctt aacactactt attgtacctt tattatctat agtagtccct ttagaattat
      961 ttgtaactgt agttatctta ccaccattag tcacttttac ttgacttgct ccagatgcta
     1021 ctgttaaact accaatctca cctttagaat tattttctat cttggctcca tttttatcat
     1081 taacctttaa gttagttatt tttccatagt taacaaaagt tccatctttt acatcatcta
     1141 taactacatc atccactttt gcatagttat ttacatctcc attaggcatg ttgatagtta
     1201 cagtctttgt atatgtacca tttaagttta ctgttactgc tttatcagtt tgtattgtaa
     1261 atgcttcttt aacctcacta gttggcttaa agtttataac atcattagca gtagctttat
     1321 ctatagctga ttttaattca gaaattgttt tagcttcaac tgtttttact tcttgtaatg
     1381 acttcatttc attaaatgct gtctcattac cattcccacc aactttagtt atcttatcaa
     1441 aactcttaga gttaactaga gatttttgtg aagctgataa gttctttcca actaaaacta
     1501 ctggtgattg atttttagca cctaatacac ctactgctag tgcatctata agttggtctt
     1561 gtttattcat accatcttta gttacataag cattttttaa atctgtcttt ttataaaatt
     1621 cttttattac ttttgcattt gtatcatttc tatctgttcc acctagtctt gtactatttg
     1681 gtagtttatt tttaacagct tcagaaattg aactctctcc acctactaca taagattgag
     1741 ttattccagc atcttttata aatttgtctg caactgctgt tccattttta gaatcagcaa
     1801 gtattactgg catattgttt tgtgcagctg gtgctcctac acttacagca tctgcaagtc
     1861 ctttttcacc attaactaca gctattttct taacatcact tatagcatct aatttctttg
     1921 ctaattctaa ggatgtttga tatctctcag ctccagagat tctctcaaaa gatattttta
     1981 aatcttttat ttctttttct atatttgtac ttaatacaga agttccacct attaagtata
     2041 cttttttagc ttttaatctt tgtatttctg ctttcgtctt atcatttaat ttatctttac
     2101 ttgttaaaag tattggagca ttttttgctt ttgcaaatgg tgttgcagat agagcatctg
     2161 ctatagatga gtcgtttacg attactacct catcagcatt tttccatcca tcttgactta
     2221 ttttaacagc agtttcatat ctttcttgcc ctgttaaatt tgttgccaca gtttgtgcac
     2281 tagctatgcc tgctgttgaa cttccagcta tcattgtaac tgtaagcatt gcagcaatct
     2341 tctttggtat tttcatttta ttttcttccc ccttgtccat ttgatattac ttaatttttt
     2401 aactttgttc ccgttctaat tctaaaggat acttaatatc taattttaaa gaggtttcta
     2461 actataatga tttcataatt aatttgtaat tattttgtta cattgcagtc attatgtaag
     2521 gaataaagaa attttcttat tgattgaaaa atttgtaaat ttatatttta aggtaagttt
     2581 gatttttatg ttaatgaatt gttataaaaa atagggtttt gtataaaaaa agtagccttt
     2641 agaattaaaa gtgctactct ttttacaaat aaattttatt atttatactt gtaattatat
     2701 attaaataac caattttatc catatgaaaa acaaataatt acgatatttt tttaattatt
     2761 ctttatattt acattttaat tcaaattact tttgtaaaga ttatatctgt tgcatatact
     2821 actttaagtg ctaatatatc tccccctaaa ttagaatcct cgttatctca atagacgttt
     2881 tctactgtca aagttaccaa catttgaaac ttattaaatt tttatataaa aaagacctag
     2941 aatataaatt ccaagtcatt ttttattaaa tttatttttt acaatataat attgtcatga
     3001 ttaaagaaca caaatcatac acaaattggt cataaatctt acataaatca tctacaaaaa
     3061 atacattatt tatattaaat ctatataact aaattaagag catattgtac aatatgctct
     3121 tagaaaagat atttcttgtt tatagtttat agtatttctc tatgattttt atttttatca
     3181 tttcaaaaat aaaaattaag attacagtta ttatcatatt ttgtgtacta ttttctataa
     3241 tattataatg aaacaatgaa aaaacaataa ttaatgaaat tacgtttata gccccagaaa
     3301 tcaaaaatgc ctttttctta ttattcatat attccctctc cagattatct aaactagtct
     3361 atatcaagca tttttaagta cttatcatta actttatata tatttttttc tttagacaaa
     3421 atctctatct cttcaagatt attaaacact tccatcaact ggtcaactaa ttcaatttcc
     3481 tttattccag cctttaagta tctactttta ttctttttta tataattttc taatgtcata
     3541 gaatagttat ctttactaca gatatatttt aatatatgtt cttctgttgc tgatagagtt
     3601 atgtcatttt caaacaattc ctcttttaat atactttcta aagattttct atcatgcata
     3661 ttacgcatct cattaataga ttgtattata gacttgagca taaactctat aaatacagtt
     3721 aaattatttc ctttgttttc tacatcaagt atagccttat aatacttagt tctgttttta
     3781 gatatcatat atgatattga aaactccttg aaagtatcat atcctttatc aatcaaatat
     3841 agatatgata aggctcttga tgttcttcca ttaccatcac taaaaggatg aacatataca
     3901 aagtaaaaat gaattatagc acttttaatt aaattactta ctttgctatt ttccataaaa
     3961 tctattaatt tactcataaa gtcatatatc ttcaaaggtt caagccctat atgtataatc
     4021 tcaccttttg aatcacatac atatactttt tcagttctat actcatattc ttctgaatcc
     4081 aagcagtttt cgcccaatat atgatgcaaa tcatatataa atttgtgact atataattta
     4141 tctaagttgt ctaatccata ttctaaggct ctatgattat tgtaaatcat atattcactt
     4201 ttattacttg gtttcatctt tcctctaatt atagattttg caatctttct atttgaaaaa
     4261 gcaccttcta ttacactaga ataataagac tctagtgcca aatcattttt atcttctatt
     4321 attttaaata tcttacttga tgttaattta tctatttcat ttattaaatt taatatattt
     4381 tcagtttcat gatagtatag ttctttatta tcaaaactat ttatagaaag tacgatttta
     4441 tttccagtaa agtatttgtt tttgtattct tctattgtca gtttaatcac caccttagat
     4501 tatctttatc tattaatatt aacaaaaagt attaattttt acactatttt tgattatttg
     4561 ttttataatt atcaaactca atttaacgtt aaagcataat aaattttaat aaataatgca
     4621 aaaatttaag aataagcatt taaaatatat gtcacaggaa gtttacaact attatttata
     4681 atacattagt tatatattat aatatctcga caatgtctta acaatatctc gattatatat
     4741 tttaatatgt aactaatatg ttataatatt ttaattaaat taaataaatt tatatttttt
     4801 tgaaattact taatatttta tataaaaatg aaaaagcacc tcattctgat taaaaatctt
     4861 tctgagatac tttttaaaat attaaatact acatatagct tacataagtt taaaatttaa
     4921 tctattataa aattacccta attgccaaac tttttaatat aaattttcca acatcctaca
     4981 aatataatca atagatatag aatcctaact tacaccaata tatatttatt taaaatagtc
     5041 ctaaaatacc tgtaatagct cccactacta tcagtataca cattattttt attggagaaa
     5101 gacctttttt taaagcaaag agtactaata aagtaagtac caaaggaatt aacccaggaa
     5161 atatcttatc aagtaaatcc gtttgaagac taaatttaaa atcaccacta gtataactta
     5221 ttggtgtaga taaattaata aacctaccta caagtccccc catgactaag gtacctagta
     5281 tagaagcccc ttctataacc ttatttacta ttccaccttg aagtatactt tcaacagctt
     5341 ttttcccata cttatatcca tttgtccaca ttccaaaaga aattgaagtc attattatat
     5401 attgagctat tacaaataat ataggtcctg caattgatgc tcctccctca gttaaaccaa
     5461 tacaaacagc caacactata ggagttataa ctccttgagt taaagtatcg ccaattcccg
     5521 ctagtggacc catcaagcct gttttgatag cattcatacc atctccactt atttcatctg
     5581 ctccattagc tttttcttct tccatagcta ttgttattcc atgtataaca catccacata
     5641 taggttctgt gttaaaaaat gctagatgag tctccacttc ttgttttaac tcttccttat
     5701 ctggatataa ttttttaagt actggcaaca ttgaatgtga aaaagctgtt gattgcaatc
     5761 tttcataatt gtaattagat tgtgcaaaga aaaaccatct taaccatgat tttattacat
     5821 ctttcttgct taacgttttc ttagatactt cattttttat atctgacata atattttccc
     5881 cctcacatgt atttaagatg tagcactatc ttttccgtac ttaattgaag taattgtaag
     5941 agcaagtatt actccaataa cagatattac tattatatct actttaaaat aaacagccat
     6001 tagtattcct aatatgaaaa agggcatagt aaacttgttt ccaatcaatt ttaaattcat
     6061 agcaatccca agtgctggca acatagcccc aattacatta aatacatgta acacattatc
     6121 attcattact tccaacatac catctatcgc atttggacca aaataaacaa ctaataatgc
     6181 tggtataaaa ctcattgcaa ataacagtat ctgtggtggt actatattta taaatgctac
     6241 tctatcaaca ttcccttttt gaacctctct atcagcccaa tgtgcaaaaa aagaatttac
     6301 tgtcatcttt ccaatccaaa gtacagttgc aacagttccc aatggtacag ctattgccat
     6361 tgcagtactt acatctagct tagatgctat agctaaagca gtacctacat atcctgcaaa
     6421 agctgggtcc cccatctgag ctccccctgc tgatataaaa cctagatata tcatatttat
     6481 acctgctcct ataattgctc cttgaacagg gtctcctaat ataattcccg ttacaaatcc
     6541 agccaataga ggtctattcc atgtaaaaaa tccaacataa gtcaaccacg gactccaaga
     6601 aagataataa aaaattgcta ttaatactgc ttgaattagt gaaatgtgca tattcttcct
     6661 ccctattttc ttttaaagat ttacaagata gtcttcttta taataatgtt cctacatcaa
     6721 ttttctttgc atctggtact atttgtataa agcatttaac atcttttgat attagctctc
     6781 taaatatttc tttttcttca tctgacacag atatattttt ataaaaactt tttctaccaa
     6841 gccctgctcc catacctcca acattcaatt cctttaaatc taccccgcta tttactaaac
     6901 ctaagacagt tttagggtat ttgaccaata ctattaaatt ttcatctcca ttatgtgatt
     6961 ttaagacttc agcacctgat tctacatcat gtacttcaac cttaacagtt gatggagctg
     7021 ccatttgtaa aacttgaact ataaatgggt cctttactac taaatcatcc acgattacta
     7081 tcctttttgc tgatgtaatc ttacaccaag cagtaataac ttgcccatgt attaatctat
     7141 catcaattct tgttaatgct atattactca taattattcc tccagatttt taatttattt
     7201 tacaacttta aaacagtttt aacatctttg attcctgata tcccaacttc ctcacataaa
     7261 ttcttcaagt cttttaactt catagtatct ctgtttaaaa ataactctaa aagcataggt
     7321 aaatttacac ctgtcaaaca ttctaactca cataccttag caaatttatt tattataata
     7381 gcagatgtat taaatggagt tccgccataa aaatcaagca atactaaaac cccttcatcc
     7441 ttatatttct caattccatc ttctaacttt ctactaaact catctatgct gtcaccatgg
     7501 tttaatccta aagtttctac attttcctgt ttgcctacta ttaattcagc actttctaac
     7561 attgctttag ccatatttcc atgtgtggct ataattattc ctgccatatg aatcatacct
     7621 ttcttaacct tttttatatg gattattatt tagtactcta atctaattat ctatattaat
     7681 cattatctta ccaaagaaaa tatccctttt gtatactttt tcaaaataag ctggtacttc
     7741 ttctaaattt attctatgtg ttactaattt ttcaacattc atgtcaccct tttgcatatg
     7801 atacaatcca gcactccatt cttttcctgg gaatggaaag gagtttccaa accaagttcc
     7861 ctttacagtt aattcacttc ttactatctt ttcaaattgc tctctagtca aagctacatc
     7921 cccatatggt acacctgcat acaatactgt acctcccttt ttagctagca acagtacttg
     7981 accacatgtc agtggagtac cagccgattc aataacaata tctgcaccat ctccatcagt
     8041 taaccttttt atttcttcta caatattctt ttcttttgca tttatacaaa tatctgcccc
     8101 taactctttt gccaagtcta acttctcatc aaatacatcc acagctatta tttttgtaga
     8161 accaaatatt tttgcccatt gtattgaaaa taatcctatt ggacctgtac caagtactac
     8221 aacagtatct ccaactttag cttctgacct aaaaagacca tgtcctgcta tacatactgg
     8281 ttctagcgca gcggcagtct cataacttat ctcatctggt atttttatta aatttctctc
     8341 tttcaccttt gtatactctg caaaacaacc tccaagttct ttatttccta ttattgctac
     8401 attattacat cttgaataca agcctttttt acattcatca cattcaaaac atggcatagc
     8461 tggacaaaca gcaactctat ctcctatttt aaaactcctt acttctttac caacctgtgc
     8521 cacttctcca gaaaattcat gccctaaaat ttctccaacc atatgtggac ctgtctttga
     8581 atattttgat atatcagaac cacatattcc agctactttt actttaatta ttacatcatc
     8641 tttttctaat atttttggta catccacatc ctccactctt gtgtctctta taccatagaa
     8701 tctaactgac ttcactatta accaccccta ctttttattt gagaatatat ccctattgtt
     8761 tatatgttaa atatctaaag caactttcat gccaatatat gtaagcattg tattcatgca
     8821 ttttataaaa ttatcattaa atgtgtgtca aagtgtgtca aaagtttctt atattaaaac
     8881 ttatgtgtgt caatataaac gacactaaca ttttatatta gttctcttat tataagtttt
     8941 ataaaatgta ctttttttgt tatttttata aaattgttcg gaaatttccc ttctatttgt
     9001 gatataatat taaatataag gtatcaatat aaattttcat gcgaatatca gaactttttt
     9061 gacactaatg ccttattcaa tataataatt taactttttg gaggttgttt atgaaaaaag
     9121 tgtatcaagg aaagactaaa gatgtttttg aattagataa tggaaattac ttacttaaat
     9181 ttaaagacga tgtaactggt aaagatggag tatttgaccc aggcgaaaat agtgtaggtc
     9241 taagtataga tggaattggt agagctaatt tagagacatc tgttaagttc tttgaaattc
     9301 taaacaatgc tggaattaaa actcattatg taagtgctaa tttagaagaa gcaactatgg
     9361 aagttctacc agcaaaagtt tttggtaatg gattagaagt tatttgtcgt tatagagctg
     9421 ttggtagttt cttacgtcgt tatggttcat gtgttgaaga aggtgctaaa ctagattgtt
     9481 acgtagaagc aactttaaaa gatgatgacc gttgtgaccc tcttataaca tctgaaggtt
     9541 tagaagcttt aaacattatg actcaagctc aatttgattc aatgaaaagc atgactcaaa
     9601 aaatttctaa catagttcgc gatactatag ctgaaaaagg tcttgagctt tatgatatta
     9661 aatttgaatt tggattctac aatgatgaag taatcttaat agatgaaata gcatctggaa
     9721 atatgcgtgt ttataaagat ggtgtaatag ttgaccctat ggatttaact gctcttttat
     9781 tagataaata gtatatacat ataatttaca aatataataa acttataaat aagataagct
     9841 atgaagtaaa gactttttaa atgttgatta tttttaaaca ttttctcgcc tttaatttca
     9901 tagcttattt aaattaatat actctaatta gtagataata gctttaaccc tacaattccc
     9961 accacaataa aacctataca tgcaattctt gatatactaa taggctcatt taaaatagcc
    10021 atgcctacaa tagctgtacc gacggtacca attccagtcc atattgcata tgaagttcca
    10081 agtggaagat gttttagtgc taatgacaaa aaataaaaac ttacaatcat tccaacaaca
    10141 gtaagtatac ttggagttaa tttagaaaat ccatgtgaat tttttagttg aaaagcccaa
    10201 aacacttcaa acaaacctgc aacaaacaaa aataaccatt tcataaattc atccctcttt
    10261 tcaaatatgt ctcttatttt tccaataaaa taacctgaga aatattataa aatatctccc
    10321 aggtttttgt ccttccgtgt tcacaacaaa aactatgttg tgggttttat ctcggaccag
    10381 accaatcatt aataattgcg gaaccctata aaactctatt aattattcta ttttatctat
    10441 aataatacta tcaacatata taaaaaaagt caatatatgg gttccatata taataaaaat
    10501 aacttttata taccttttaa tattcttatt cacttctctc catacccatt tgggtcaatc
    10561 taagaatatc taatttttat ttaatatgtt ataataacat aaaaatattg aaaggagtaa
    10621 tttctatgaa tttctataaa attgcagtat gtcagatgat tactacagaa aataaaattg
    10681 aaaatatcaa tcatgctgta gatatggtaa cagaagctgc catcaatgga tctaaaattg
    10741 tagttttgcc agaaatgttt aactgtccat atgaaaataa atattttcct aaatttgctg
    10801 aagaatatcc aggtgaaaca acaacaatat tgagtaaatt agctgagaaa catggaattt
    10861 atctagtttc tggtagtatt cctgagttag aagatggaaa aatctataat acttgctatg
    10921 tatttgataa aaatggagct ctaattggaa aacatcgtaa aatgcactta tttgacattg
    10981 aagttacagg aaaagttagt tttaaagaat cagatactct tacagctgga aatgatgtca
    11041 ctgtaataga taccgaatat ggaaaagttg gtatagctat ttgctatgat attcgtttcc
    11101 ctgagttatc acgtttaatg gctcttaaag gtgctgaaat cgttatctta cctgctgcat
    11161 ttaatatgac tactggtccc gcccattggg agttatctat aagaatgcgt gctttagata
    11221 atcagatatt ctatgttggt gctgcacctg ctagaaatat gaatgcttct tatatagctt
    11281 ttggaaattc aagaatttca gacccttggg gaagaataat tgctcaagct gatgaaaaag
    11341 aatgtattat ttatgctgac attgatagag atttaattcc tgacataaga caacagttac
    11401 cacttcttaa gcacagaaga actgatttat atgaacttaa tactttgaaa taaaacagaa
    11461 cataacccca taaatcgtaa attaagtgtt aaaaaaattt atggggttct cattaatttg
    11521 atttaaaatt aatttcataa aaataatgct aaaattaatt taattaaata atactaataa
    11581 ttactaatga ttatgctaat tatcagcatt tactaattta atcactatta gttatttctt
    11641 ttattaaata tctttacttt tttacttatt atgtcttcta gctttacatt tggattatgg
    11701 tatttctttc tatttttagt cacatctttc tattgaatta cttgcttaaa acaccaatgc
    11761 acacatgcca gataatgttc acaattatgt agaaatcttg ctctaccttc ttcaatgttg
    11821 atattatctc tcctagttga tattatcttt cctaaaattt cttttaatta aaaaacaaca
    11881 ttagttgata tatcaagtat attttaatca actgaaaaaa acaataataa ttgatatatc
    11941 aactaattaa tgtagattaa ttcattttta taatttatat actttttaat taatctacct
    12001 tatttaatta aaatccttcc tttctattta tccattttca acttaaatta taagatttca
    12061 tcagctatat ttttgcatac caataagtat taaatatcaa atatatattc tattaaaatt
    12121 tctaataatt tcatccttga tttatttaat atataaaaat atactaactt taatgattaa
    12181 gttttgaaat ataactaaaa atttgataat ttattgagat ttttatacta aaatatacat
    12241 actatacaaa cttaatttag aagggagcat tcttatgaac aataaaatac tcgtcgtaga
    12301 tgatgaggaa ggtataataa cactcttaaa agattacttt gaaatgaatg gttatgaggt
    12361 ttacactgct caaagtggaa aagacgcatt aaaaaaaata tccaaaaatc cagatatcat
    12421 tctacttgat ataaacatgc ctgaaataga tggaattgaa gtttgtaata gaattagaga
    12481 ttatgtatca tgccctattc tatttcttac agctagaatt gaaaacactg acaagataaa
    12541 tggttttcgt gctggtgctg atgattatat tgtaaaacct tttgatttag acgaacttgg
    12601 agctagagta tctgcccatt taagacgtga acaaaggaag tcaaatcaaa ctaaaattaa
    12661 attttataat gatttaacaa tagattacga aaaaaggtta atttgtatat ataataatca
    12721 gatttcactt tcaaaaaagg aatttgatat agtagagctt ctctctatga atcctggaca
    12781 agtatttgat aaagaaaaaa tatatgatag agtctgggga tacaatagca atggaaatag
    12841 tgatgttata atggaacaca ttagaaaaat acgaatcaaa ctatcaaaac atactcttga
    12901 aaattatata gaaacagtct ggggagttgg ttataaatgg ataaaataaa taatatgtca
    12961 ttaaaaaaag ctttctttgt tcttacttta tcttcactaa ttatagcatc agtacttact
    13021 actttcgcat acattttact taataatcta tataattcta tacaagataa gtatttaaaa
    13081 acacctataa atacaggtat tataaccata gttcaaaaca atgtgaacca atttagtgat
    13141 tatgataaaa cattacttaa tataatcaac atactccagc ttgtacttcc acttatattt
    13201 tttataggac ttttattatt agctgatata attttttaca aggtaaaatt aaaaacaccc
    13261 atagaaatac tcaataaagg tgcaatggaa atatccaaca acaatttaga cttttgctta
    13321 gaatataata ataatgatga attaggtaat ctatgtaatg cttttgaaaa aatgaggtct
    13381 gaactaaata aaaacaacat aaagatgtgg actatgatta atgatagaaa acaacttaat
    13441 gctgcttttt ctcatgattt aagaaatccc ctaacagttc taaaaggtta ctcaaactat
    13501 ttaacaaaat acataccaac aggtaagctt agtgatgaga agattttatc aaccacacaa
    13561 cttatgtctg agcatattaa cagaattgaa tactatgtag aaaatatgag taatgctcaa
    13621 cgattagaag atttagttgt ttcaaaatct atgtcgaata taaacaagtt tatagaaaac
    13681 ttagatgaaa atatatctat cattgctaaa caagaaggaa aatcttttac acttaaaaat
    13741 caaataaata atataaatct attttttgat gaaaatatca ttcttagagt cgtcgaaaat
    13801 ataatatcga atgcttttag atatgctaga aataatgtat ccatacttat atatcttgaa
    13861 caagaactcc ttacctttgt aattgaagat gatggtatag gatttagtaa ggaatctcta
    13921 aaattagctt taagaccttt ctatagagat aagactttaa atgacagcaa tgcacacttt
    13981 ggtatgggtc tttatatctc aaaaatatta tgtgaaaaac atggtggctc tatttctatt
    14041 gaaaataatt ctactaacag tgctaaaatt actgctaaat tctcaacaag aaattaaaat
    14101 gattttgtaa gctttcactg ctattatata aaatttgtta gtttagaatt tataaaatgt
    14161 atttcaattt ataaccaata tatatactat tttgtagaaa ttgtaagagt tgcttcaatt
    14221 ataatatttt ggcaaaaggc atttgaaaca ataatagaaa tatatattta aatatgtaga
    14281 atagtatgaa attagaattt tggaggtgat tatattaaaa gttttgctaa taatattaca
    14341 ttctctcgta ttgtgtttgc attgctaatg cttagtttta cattctgttc actgcctttc
    14401 tggatatgtt atttttggtg tggaattagt gatatacttg atggtcttat tgcccgaaag
    14461 ttgagacaac aaagtggaat aggtgcaaag ttagatagta ttgctgattt cattttttcg
    14521 gttacaattt tggttactgt cggaaaaaat attgctcttc ccatgtatct atggtggtgt
    14581 attattgcaa tagcattgtt acggttgatt agttacagta ttggtttttt taagtatcgc
    14641 acattttcat cgcttcatac tttgatgaat aaaatcactg gaatttctat ctttgcgttt
    14701 ccattactct atatttgctt tggtcttgat gttgcaggaa ttatgatatg tatcgtggct
    14761 tttctttctt cttttgaaga aatagcaatt atgataaaat caaaagaatt aaatcgtgat
    14821 ataaaaagta tatttatgtg aaaacttaga atttgtgaca aaaataattt atataataat
    14881 gaggaagtaa aacataaaaa attatccaca agtttatgtg taaaatagtt ttaaagcaat
    14941 agagttgtat tgtaaagcct ttagtgcata aattacattt taaattaaaa atgatactga
    15001 aactgcttat cagcactgcg aattatccgc aaatagtgaa gactttttag atttaagcta
    15061 aaagttggga aaaaattgag ttttaaaact tacactcttc ttatatagaa aaggagagtg
    15121 ttttttatga ttataaaagc aaaacaatta tcaaaaatat atggttctaa taacaataaa
    15181 gttatcgcac ttaataatgt aaatttagaa ataaactcag gtgaatttgt ttctgtaatt
    15241 ggaccttctg gaagtggaaa aagcacactt ttacatattt taagtggatt agataatcct
    15301 acctctggac aagtgttact tgatgataaa gatatatata aacacactga aaaagaacta
    15361 tctgcactta gaagaaaatc ctttggattc gtctttcaac aatttaatct tttacctgtt
    15421 cttacagcat ctgaaaatat ttcaatgcct gtacttctag ataaaaaaca acctgataaa
    15481 ggctatttaa atgaaatttc atcattactt ggaattgcag atagactcaa tcatcttccc
    15541 catgaacttt caggcggtca gcaacaaaga gttgcaattg ctagagcact tattgcaaaa
    15601 ccagatataa tatttgctga tgagcctaca ggaaacttgg acagtaaaag tggcagtgaa
    15661 gttatgaatc ttcttataaa aacttcaaaa cagtttggaa agactttagt ggtaattact
    15721 catgatgata gaattgcaaa acttgctgat agaaaaattt caattattga tggtgttctt
    15781 atggaggtga aatagaaatg aagaattacc tttcactttc aataaaagaa ttaaaaagcc
    15841 agaaacttat gactacattc atcattatag caatagtact atcaactatt atgacaactg
    15901 tggttggaca gtcaattggt atcctacaaa atttaagaat tgaacaagcc cgttctttta
    15961 atggtgatag acatgtatcc tttcaccaac tcactaaaaa tcaagttgat gacataaaga
    16021 aagatgatag agtttatcaa gctggtactt caataactat tggcagtagt aaaataaagg
    16081 attctggtat ctctgtactt gtaaaagagt atgataaaac aggactttct aactacccaa
    16141 aattaatgaa attaaaatct ggacatttgc ctaaagataa aaacgaaata gccttagatg
    16201 aaaacacact aaagcttatg ggtataaaac caagactagg agtgactata cctatgaatt
    16261 tagatatttc acttttaaat gataccatac caccatataa ttacacagct aactttaaat
    16321 tgagtggcat tttagaggat gattatacag gatatgtaag tggtatagta aatggtattg
    16381 taggtaaagg tacatcagaa aatctattac ctaagagata tactttatcc tctttggatt
    16441 ttaaaataaa acagcaagaa aagtttcaag aaatagtaaa tcaattagct aaaaaaataa
    16501 atctttctca caattcaatt caatataatt ggatttactt aaatgctctt aagatacagt
    16561 ttgaaaaaga tgaaaatagt tctaatagtg atggtatatc tatgattata ttggtatctt
    16621 tatttgttgc cttattggtt ttactggctt ctggacttgt aatctataat attttaaaaa
    16681 tctctgttac aaagaaaatt aaagagtatg gatgtttaag agcaatagga gctgaaccaa
    16741 accagatata taagatagtt attttacaaa tcttaatttt atgtactgtt gccataccta
    16801 ttggagctgt aattggaatt atatcttcga aaggcataac tggaatggtc actaatatct
    16861 taaatccaga tatacttcta gcaaatgata ataaagaaat tactgagctt atacataaaa
    16921 atacaacagc atatatgttc ccattagtat taagcactaa tgtatctttg attttttcac
    16981 ttatttcagc attaccatca gcaatatatg cttcacatgt ctctcccaaa attgctatgg
    17041 ctggtagtac taccaaaatc aaaagaaaaa ttaaaagaga aaaaacaata aaaaactttg
    17101 aaagacatct agcatggcta aacttaaaaa gaaataaagg aagaactata ataactatac
    17161 tatcattatt tatgagtata acagtattcg ttgcactgag tgagttctct aatatattag
    17221 atgtatctag gtcagtaagt aatttaaaag aaggagattt ttccttaaca aatgaaatat
    17281 ctggttttga taaatcaaca ctagataaaa tagctaaaat gaaaaacgtc aatcgcactt
    17341 cctttataaa gtactctgaa tacaaacagg gtgaaataga tacagatata aattttgaaa
    17401 atagtggtga gatgttaaaa atcattggaa ttgatgagca aactttaaaa gacttaatgc
    17461 cttctattac aaattctata ctagaagact ttaaaaatgg ttctatctgt tttataaaaa
    17521 atccgattgc tatttctaca ccaggtgtaa aaactagata tacaaattta aaacctaaag
    17581 atagtatcac aatcaacaaa aaacaactag atatatatag tacagtagat aaaatgttct
    17641 ttttacaagg caatggctgg ataaatggtg ttgatgttat tgtatatgat tctgtttata
    17701 acactttgac aaataaaaac aagttcaacc agataaatat ttatgctaaa gataaatcaa
    17761 aattagaaca aataagattg tctattgaac agatttgtga aaataatcct ggctctcatt
    17821 ggatatcata tattgaatca gataaacaac ttaaagagag ttttaaacaa atagaatttc
    17881 tagcatgggc agttatatta tttgtgggat tgattggtac tttaaacatc attaacacaa
    17941 ctcatacaaa tataaatact aggactaatg agattggagt taaaagagct attggtatga
    18001 gtaataggag cttatataaa atgtttttat gggaaggtgt ttattatgga atttttgctg
    18061 ctatatttgg ttcaattgct gggtatgcca gtgctattat tataaacatg gcaactatag
    18121 aaaagcttga tttcactaat ataccaatta cttcaatttt acaagctact attatttctg
    18181 tacttacatg tattatagct actcttattc cgttaagaaa agttaaaaag atgaatataa
    18241 ttgactgtat agatatcaat ttataactat tttacagata ataatataaa ttaaattatc
    18301 aatgactgtc tctattttct ttcaaatcta actaataaat ctttttaact ataatataag
    18361 ctttaaaaaa ggcctgtctc aaaatagaga taagcctttt ttcattgtcg aaataatgaa
    18421 aatatattta acttcacaaa aaaagagtgc ctcacgaatt aaaaatttcg ctttgagaca
    18481 ctctccttta atttaaaata tatagttaaa tgctatgcca aaatttcaca catgctccac
    18541 ctgattttga attttctatt ttaacagaac ctccaagctg ttccactaat tgtttgacaa
    18601 tgtaaagccc aagaccagaa tgtccacctt ttgtctgcct agcttcatct cctcgataaa
    18661 atttatcaag agcctttttt aaatctttag agctaaaccc tctaccagaa tcacaaatct
    18721 cataagaaat acaatttttt tcatccttta cagtaatact aatattacca cctgatggag
    18781 tgtattgcag actgttggat atgatattat caaaaattcg tgtcaaccta tccacgtcga
    18841 tttgaattgg ggattgtata ttcccctgca ttttcaatat aagttcaact tccttttgat
    18901 gagcctgtaa ttcatagtct tgcacctttt gcctcaaaaa ttcaggtaaa tttataggaa
    18961 caagatttaa ttgtatattt gacttttcta agtcagacgt atattgcatc ttttggacaa
    19021 gagcagcact tttttctgta ttttctctta tcactgtaag atacctatga agtttttcat
    19081 tgtcatctgt attattacca ataagtgcat ctgtatatcc caaaataata gaaagaggag
    19141 attttaaatc atgtgctaga gcttccacca tttcaacacg ttcctgctcc atcttccact
    19201 gtgcagataa agagcctttt aattcgtctt tcatttcaga aaatgcacta caaagtttac
    19261 cgagttcatt atctgaataa tagtcgattt caaaatcaag gtccttttct tttatcttct
    19321 tggacgcatc aatcaataga tgtaatggtt gattgatatt ctttacaaag cgcttagaaa
    19381 gccatctagt aaaacccacg atatatagaa atggagaaaa caaagccatt ataataactg
    19441 caaatacaaa tctccctcta atatttgcaa aggtgatttt cacttggtag aatagaataa
    19501 cagcaccctc aatctttcca ttatcccctt tgattggaac agtatggata taaccacctt
    19561 tacgaacagt tttattgata aaattattaa ataattcttc ttttgtttta aatagttttt
    19621 tggggttagt accatataaa atattgccat tattatccac aacttgatat agcatatcat
    19681 ccccacgaat cgttcttttt aaaccttctt cattcgattg tgataacaaa gctatgtttt
    19741 tttcattgat gtatttttca attctaggaa cttgtcgctc ataatagttt ggtggataga
    19801 tatccttatt taaggaatga atatacaaat agagagcaaa tacataagta atcactgtgg
    19861 caactatact ggctattata ataaaaataa aagtatgtct aaattgggta ataagggatt
    19921 gatttttcat ttaataacct ctctctcttt acattttatt ccacttatac ccaatacccc
    19981 aaactgtgga aatatattct ttttctggtg tcacagcaga aaacttagct cgtatttttt
    20041 ttactcgttc aacaacagtt gaggaatcac cttcagaatc acacccccat actttttcat
    20101 agatttgttc tcttgagaaa acttgtcctg catggagtgc tagtaattca acaatatcat
    20161 actctatttt tgttaaatca atattcttac catcaatttt aattgcacgt tccttcatat
    20221 ataagcataa cttcccaaaa tacaaagtag atctcttgtt ctcttcattg atatactgtg
    20281 aacgcttttc cctacgcaga ttagcttcaa tccttgccat aagttcacgc agtccaaatg
    20341 gctttgttac ataatcatcc cctccaaagg tcaacccttt gattttgtcg gtttctgatt
    20401 gctttgcact taaaaatata attgggcata aaacatcatc tctaattgcc tgacatacct
    20461 caaatccatt cattttaggc atcataatat ccagtataat aaggtcaggc tcctgttttg
    20521 ataactctat acctgcctga ccatcataag ctatcaacac ttcatgtcct tttgccttca
    20581 attcatcctc aagtagcatt actaggtcca tttcatcatc aataatcaat attttactca
    20641 atataacacc acctttctct tatgggaagg tcagtattaa aacaatattc gtctactcat
    20701 aacttttcct tccctcccac attttaaacc aaataacgcc tcctatcaag aatataatca
    20761 aacctattgc tactactata agctctatac tagctgtttg catcacttta gagtaaaatg
    20821 cctcagttga aatagttcca gcttctttaa taaaataaat tcctggaagc atacctagtt
    20881 ttactggcca tgtccatgga acaaatgccc atactttttc accaacgcta gttaatccaa
    20941 gtattgctgc catcaaaatt ccaccaatac taataccaat agatgcaccc ataccccatg
    21001 caaaactcac ccaaagatga atagctaata gtggaagtgt cccaatcacc acaagtcctg
    21061 ctgctgacag gaataaccat attgttgctc cagatggcac tgcaatactc attcctatgc
    21121 aaagtatcaa cgtagcaata aatgtgcata tagttaggca aaacagaaga aaaagaaatt
    21181 ttcccagata taatctgaca cgagaaatac ctacacataa aaaaccatta aaatttccag
    21241 caagctcttc ctcctgcact ataaatcctg ctaaaatacc tactccaata ggaatgatga
    21301 atacagtcca tactgtaaaa aatccttcaa aagcaaattc ttgtgtactt ccagatttag
    21361 ttgtgagata aaaaaccaca cataatgaaa aaataatagg catacaaaga gtaagccact
    21421 ggacagctgt cctctttgct cgaagccatt ctgatgataa tagttttatc atttgtcatc
    21481 cctcctattg aaccaagctg cagtaagtgc tgttaatact ataaacacaa ccaaagaaac
    21541 aacaatccca ataggaatca ctgaagtatt caaaagtggg tctccagctt ctaatatagt
    21601 accgttagga tgtatgttga tgattgggca taccattcta actgcccaac tccaaggtac
    21661 tgcaatccaa aatggttttg tcgcagcaag aacaccaaat atcataccta aagctccaac
    21721 tcccatactt aggaacatac ctttccatgt agctagccat agctgaagtg gaagtatagc
    21781 aagagaaaca acccagcata caatacttgc ccctataatc tgtccaaaag gaactggacc
    21841 agctttcaat attaaaccag ttataattgt tacgaatatt aaaactagcg ttgaaataaa
    21901 actgtagact gccatagcta taactttatt aatccaaagt gtcataggag acacattgtg
    21961 tgtacgtaaa gcacgataat ttccagcttt tttttcctgg aaagctacca aagtagcaaa
    22021 caatgcaaat ccaataggca gaaataaaaa tgaccaccag ttaaaaatta atgctaaaag
    22081 attttgccac gcccaagaag ttgtttgaga taatggattt tgcatgagtg ttgattgcat
    22141 tataaatgca tatgctgcaa aagacactgg gaaaaaaaca ataagtttac ccataaatgt
    22201 tcttttatac tttaaaagtt ctgattgtaa agcattcatc tgttttgtcc tcctttaaga
    22261 ataacatctg taaaaaattc ttctagattt tcattagagt caggcattcc ttgaaataat
    22321 agtcgtcctc catttataat tcctatatta tctacaactt gagcaacctc tgatagaata
    22381 tggctagaaa gaattacagt tatacctttt tttggaaaag aagcaatcaa ttcacgcaat
    22441 tcttgaatgc caaaggggtc aagaccattg gttggttcat ctagtattaa caactctggg
    22501 tcactcaaaa gtgcaatagc tattcctaac ctttgtttca tacccataga aaattgtgaa
    22561 gctctctttt tacctgtatt tttcaaattt actatttcca acacttcata aattttatct
    22621 ttaggtattc ccaatatttt tgtatgtact aacaaatttt cctctgctgt aaggtttcca
    22681 tacaatgcag gggattctat taaagaacct atttttgcaa gagattctcg tttccaaggc
    22741 tttctatcaa aaataatacg accatttgtt ggacgaagaa gaccaacaag cattttaagt
    22801 gttgtggact ttcctgctcc atttggtcct aaaagtccat atatactatt tcgttcaatt
    22861 tgtagagaaa cattgttaac tgccatttgt tctccatatc tttttgataa gttttttgtt
    22921 tcaagaatta aatctttcat attaatttct cccttcttgt aataccttaa atctgttact
    22981 aagagaatac taacatgaaa aaataacaat tctataacac ctactaattt taataaaatt
    23041 taaaataaaa aatagagtta ccaattttat tttggcaact ctatttaagt ttatgtttta
    23101 cagttatatt agatttaaac ttagtttcat tatcacacta acttcaaatt tactctataa
    23161 tctttaaatc aaacactaat ctattaattt atatttcttt agacatctaa tatagtttgc
    23221 tactaaataa taattattta tatcatattt atctaatcct ttaaaagaag ttatttcatc
    23281 attaagctca tcactacctt ctacaaaaac acaacctgtt tcaaagtcca tacctacaat
    23341 aatcttacag ccactataaa tttcctcttg agtatcgtac aatttttttg catttccttc
    23401 atttggaatt gtaaatacaa taggttttaa ttctttatca ctggaaatct tttgtgaaaa
    23461 aggcttgttt aacttaatat tattgataac tacatgttta aattcctctg aagtttcttc
    23521 tactattaca tattttcgct ttaaaaactc tattatttct aaaacagact tagaatttac
    23581 ttttaaaata cttttatatt tttcatataa agatttccac tgttcaattt tttcctgtgg
    23641 tacttcttgg atatgtgtac ttattttttc ttgagatatt tttttcaatt aaactctcct
    23701 ttcaatactt aaatatcctt ataaatctca cataactaaa gttacaaggt tcctacttaa
    23761 tagaattttg catacttaaa tatgtcttat taattctcta caggatatct ccgtagttcc
    23821 tacgattctt acataagtta cttattttaa attgttatta gttatattct aaaaattatt
    23881 tattttatca ctaatataat actcttaaaa actttacaaa tcaatttaaa tttgctacct
    23941 tttatttata acaacttata gtacatttct cctatgcttt tcaatatatt acttttaaaa
    24001 ggaggttttc attatgattt taaatagagc tgagcttttc cgaggatatt ctttaaatag
    24061 atttaacgag atatgcaata tattatcagt aaataaaatt aaatataagt ataaagtgaa
    24121 aaataatgct tactctaaaa aacctttttt taatgaaata acacttggca atttaggtca
    24181 aaaggaagat ttctcttatg agtacttaat ttatgttcat aaagacgatt atgaacaggc
    24241 agagtctcta ataaattcta agttgcgata gattatttat aaaacatgac attctgttgt
    24301 catgttttat atgttattat actttcaaat atgctactat attttcaaaa ttgtgtgctt
    24361 taaaactagc tttttatagt aatttaaagc ttaaaactaa ggagactcgt tatatgaaaa
    24421 taaatataaa atcaaagtta agtgaattta ttaaacagaa caatcttttt gatgacagca
    24481 gaataatatc ctaccttcct aatataacaa tagaaacaga caaaataaaa actataatga
    24541 ttaatgaggt tgtcccaact aacaccaatg acgattttta tagtgtagat aaagatgctg
    24601 attatttaaa aactactatt cctttatttg acagtgcagg aatagaagta tctagcataa
    24661 atgatatcct agatatgggt atctatataa ctaatgcagt aaaacttcct aaatcagaat
    24721 atacaataac tcgtgataca attaaattac atatgcctat tttagaagaa gaaattaaat
    24781 tatttaaaaa cctagaggta gtaatgttaa tgggagatgt tgcaaaaaaa tcttttaata
    24841 tgattactaa aaagcatata aaaaagaatg tcatcccttc catttcaaca tataaacttc
    24901 gtaataatga actttattat gataatttaa gagtatttcc atcatatatt atgactggtg
    24961 gaaacatact gattgaaaaa tcaaaatttg aaatggcatc agaagatata aaaaaaatgt
    25021 tcgagattat aaacggttga tattacaaaa taataaaaac taatataaaa taaaagtgca
    25081 tcaaaaactt ctatttatga ggcactttta ttttatatta gtgtaactat atactattaa
    25141 cataatttat tatttatatt gttcttttta atctctattc catttagtct aggtaacatt
    25201 actctttaca agattacttt atatttcttt tatatctcta acgtttttat ttaataaaac
    25261 aattattaat acaagtcaaa tatatctatt tatctaaaaa tatatctttt acagtaatat
    25321 ctggatggtg atacttcttc ctattcgtta aaaaagattt ttttacatta atagcctctt
    25381 ttggacacca gtgaaaacaa gctaggcatc tttcacactc attaccccac tttggctttt
    25441 tatcaactat acttatattc tctacaggac aaaccctttt acatgtccca catccattac
    25501 atttattttc tgcaaaaaat ttagtagttg caatttgcat attcttacct actaaacgaa
    25561 gtacaacact atctatatgt gactttaaat tgttttttcc ttctatattt ccaatctcca
    25621 agttattgat acattttgca atctcagcta ccctattagt ctgatttttc aatctttctt
    25681 cttcaacatc tggaggtgtt atcaaagcat ttccaggcat attgattaaa aaaccagcag
    25741 ataatttttt cccccttttt ttaagtaact tatctatagt aaataaacta tgtccagcta
    25801 ccccattaca agtggcaatg gcatatatat gagtattaat attaaaattt aatttctcta
    25861 caaaagactt tactatatca ggaacatcag caaaataaac aggaaaaaca attaccaata
    25921 tatcttcatt tatgtctata ttattttctt ttctatgtat agctaagggt ataacttctt
    25981 tacttccatt taacgtttct tttaaaatat ttgaaactac tagcgaattt cctgttccag
    26041 aaaaataata aatcttacta ttcattctta tccctctttc tatatttcta catcatcaat
    26101 agttaaaaag tctcttaaaa taggatttat atttactttc caattctatc caaaatatca
    26161 gtaaacaaag gcaattcttc atcagagata gatttaaatg tctctgttgc atatatactt
    26221 gcaatttcat ttaatggttc ttctaattct ctacctaaat ctgttaggaa tatttgaaac
    26281 ttacgtctat ctttaacatc tactttacgg acaattaatc ccttattttt cataacatct
    26341 aagattcttg tcgtattaga tttatcctta catgattttt cacataaatc tatctgagaa
    26401 attccatctt gctcccatag aaaccttaat aacgcataat ggtcagttgt tatatcatat
    26461 ccattttgtt taaacatctt ttttaaatca tcttttactt ttaacgaagt acttactaac
    26521 ttagttgtag cttcatatag tttctcaaaa tctttcattt tacctccatt taaataatcc
    26581 cttgctcctc ccatctatca attattccct tatattgctc aatatcttta aaagccattg
    26641 gctttaaaac agcatttata gcaataaaat tatagatttg agaaagcaca ggtggatttt
    26701 tcttttcctc tatgcaataa ataaattttt tagatacctt ttgtatcttt gattctactt
    26761 tttcagttat aggattttga ttaaatccag tttttataga taaactacca caaacataac
    26821 ctcccgaatc taagaccatg gattttataa aagaaattgc ttttgaacca cgtgcatttt
    26881 catatgtagt aactgctata catggcttac gatacaataa tctttcaagc atcatatgtg
    26941 ctctatctgt aaacaccttg aaaagtccag ttacactact tccataagtt gggctaccaa
    27001 atataacacc atcactctta gtaattatat catgaatata ctctacttta tcattttgat
    27061 tgatacactt gcccatttta taacaattta aacaaccaat acaatatgat ggattgacct
    27121 cacttaaatc aaaataatta atttttacat ctggtattaa tctttctata tctttataca
    27181 agtaagtcaa aacttttgat gtagctccat tttttctagg gcttccattt ataactgtaa
    27241 ttatcatttc tatatctcct ttttagttgt tatatcaaca ataagtatat caactatatt
    27301 tttagctgtc aatataaacc atttatttaa agctatactt acacagctta aataaaagtt
    27361 ttatttaact acatgtgctt atttaatcaa ctataaatga attattttta ataattgaca
    27421 aactaaatta atgataatat actttatgta ttacaaatgt aagtagaagg aggtatagta
    27481 tgaaaaagtt accacatatt tcagaagcag aatatcaagt tatgaaaatt atttggaaat
    27541 atgctcctat cagcactact gaagtaattg aaaagttggt agaaacaagt acatggagtc
    27601 ctaaaacaat tcaaacaatg ttattgagat tagttaaaaa aggagcttta acatatgaaa
    27661 aaaatagcag agtattcgtt tatactccac ttgttaaaga agaagaatac gtagctacag
    27721 aaagtagttc ttttttaaat cgtttttata atggtactct taattctatg gtactaaact
    27781 ttttagaaaa tgataaacta tctgaagatg atattgagga actgagagaa atcttaaata
    27841 aaaggacgac taagggggat aaataaatat gtatgcccca ttctttatac gatttttact
    27901 cagtacatta accttatcaa tattaattgt tgtaatttta cttgccaaaa aagtatttaa
    27961 aaaacatatt tctgcaaagt accaatacaa tattggattt atattgctta taatgttaat
    28021 aattccattt gtccctctta aatatattaa tcttggaaat gtatttaact atttatatac
    28081 ttttaatcaa cttggaagca gtactaatag gacttctatg ataaaaaata gtccaaattc
    28141 tataattaat aactcaaatg cattaaacga tttttcagta tccctaaacc aagttaattt
    28201 tgatagttta aatattttat tactagtatc atggataatt ggaattttaa tcatgatagc
    28261 tattactatt cattgcaaca ttaaaataaa aaatatgaaa aaatcaatac aaattttaag
    28321 agatgatgag atagtattta tatttgaaaa gtgtaaaaaa gatattggta taaataagga
    28381 ttttatacta tgcaaatcac ctattataaa tacacctatt acatttggat actttaaacc
    28441 acacattata ttaccagata agtctatatc taaattatct ttaaaagata taaaatatat
    28501 cttacttcat gaattacaac attttaaaaa taaagatata ctgataaatt atataatgtg
    28561 ctttcttcaa atattatatt ggtttaatcc tcttgtatgg tatgcattta aagaaatgcg
    28621 tatagaccgt gaaattgcat gtgatatttc agttttaaaa aagcttgata aagatagtca
    28681 tatagaatat ggacaaactc taataaactt tgtggataat atttcaagac catcaaatct
    28741 tacacttaca tcagatattg gtgggtcaaa aaaacaaata aaaaagcgac tattgaagat
    28801 aatggatttt cataatgaat caaatacgtt aaaattcaaa agcattttaa tttttacatt
    28861 gatagcttta attgtatttg gaaatattcc caaactatct attatggcag atatcaacga
    28921 aaaatataga cctacaaatg aacaaactgt gtacgaggac ttaagtcagt attttaaagg
    28981 ttttgatgga agttttgtta tgtatgattt aaaatccaag caatatcata tttacaataa
    29041 agaaaaaagt aaaacaagaa tttctccaaa ttctacttat aagatttata gtgccttatt
    29101 gggattggaa aatgggataa taacaagaaa taattcacat atcccttggg atggaaagca
    29161 tcattctaat agttcttgga atgaagacca agacttattt tctgctatgg aaaactccgt
    29221 aaactggtac tttcagactc tagataaaaa aacaggtcta aaaaacatac aaacttatct
    29281 taggcaaatt ggatatggca attatgatgt ttcaggtggt atctcaaact tttggctaga
    29341 atcttcatta aaaatatcac ctattgaaca ggtagaatta cttgaaagtt tttatacaaa
    29401 taagtttaaa tttgaagata aaaatataga aacagtaaaa gattcattgt taatatcaaa
    29461 aaaggatggg gtatcacttt ttggtaaaac aggcactgcc aatataaatg gaaaagatgt
    29521 aaatggttgg tttataggtt atgtggaaaa aaatgaaaat acttatttct ttgctacaaa
    29581 tattcaaagc aaagattatt ctaatggtag ttcagcatct aagataacat tatccatatt
    29641 aaatgacaaa aaaatctata atccttaata tatttactgt acattctaaa aaattcacat
    29701 aattttcata ttaattatca attaaattca tatacaaggc ttattatata aacatagaag
    29761 atagtaaaac tagcttaaaa acataatata ataccctata caaatagtgg caactctccc
    29821 tcacatcctc aattgttgcc actatttaat tttttgtatg aagttaaata tattttcatc
    29881 atttcaacaa tttgggtgca atacaatctc tattttgaaa caacctcttt aattgtttta
    29941 gagtttatga attatttctg atactttaaa aagattgaat tactcttgat aatcttcttt
    30001 tgtagtcatt acatatcacc tactactcaa cacatattct ttgacctatt tttacatcct
    30061 tgtttatatc caaaatattt accttcttac catctggaaa caataccatt gtcaaagtag
    30121 actttcctaa ttcgtgtatt ctctttaaat caacattaac aagaacatct ccctgtttaa
    30181 ccatatctcc ttgtttaaca gcaacatcaa agccatctcc atttaatgca actgtatcaa
    30241 ttccaacatg aattaatact tctccattag ttcctttaat cccaaatgca tgtccacttg
    30301 aaaatactgt ttctaattta cctgaaatag gagaaacaat ttttccatct ataatatcaa
    30361 tagcaaaacc atcacctaac atttttttag aaaatgtttc atctggtaca ttttctaatg
    30421 caacaatttt ccccttagct ggaaacacaa agttttcatt attttcatta aacactaatt
    30481 cttcgtcttc atcttcattt atagcttctt taggcactcc aaataaacat gttacaataa
    30541 agcagaatgc aaccacaaat attgatacta ataagtatgt gattaaatta tatccatcat
    30601 agatatacat taaataagaa ggtaaaactg ctaatccata tgaattagat tgaatatgta
    30661 aaattgataa tattgctgct cctaaacctg aagatgcaca cataataatc aaaggcttta
    30721 aattatatcg aagctgaatc ccaaataaaa caggctcact tataccaaaa agttgagata
    30781 gcattgctcc aaccgcagtt tgtttaactt gattattttt agattttttc ataaatgcta
    30841 gacatgttcc aatattcgca aatccataca ttgcacaaag agtaataagg gcattaaatc
    30901 ctgtatttgc taatagtgat gtttcaatca ttacataagt atgatgtaag ccagtaataa
    30961 cagctaatgg atatgtaaat ccaataataa atcctccaat tcctaaaggc aaatcaatca
    31021 ataagctgat gatatcaacc atttttaatt ctattgtatg cattataggg cctacaccta
    31081 acaaaataac taacattgtt attagcataa caaaaaatgg tgtgaaaata aggtctaata
    31141 cattaggcat atgtttacgg aaccattttt caagattagc tccaataaat gctgtaacaa
    31201 tagctgttaa aacacttcct tgacaaccta caataggaat aaatccaaat gccataattg
    31261 cttcaatttc atttgatggg tcagcaacag aatatgcatt aggaagtatt ggggaaacta
    31321 acataagtcc aataacaagt ccaataacag gtgttcctcc aaatacttta aatgctgacc
    31381 atacaataat tgctggtaaa aaagcaaatg ctgtttctgt aagaaccgaa acaagtgtct
    31441 gaatatacaa tggaatattt gcagaagaca ttccaaataa tccaagtaca ttatcattaa
    31501 acaaacaacc ctttaatccc aagaataatc ctgttgctgc aataactgga ataataggaa
    31561 caaatatatc tgctagagtt ctcataactt tcttaaatcc agtttcatta tttttaacta
    31621 attcatcttg ttcttttttt gataaagttt ttaatcccat tttttcaact tctgcataaa
    31681 ctttattaac tattcctgtt cctaaaataa tttgatactg tccagaagta aagaaaaccc
    31741 ctttaacctc atcaactttt tcaactttct tatcattaat aatttctcta tctttaacca
    31801 tcactcttaa tcttgtggca caatgtgtaa tagaaataat attatcttca ccaataattt
    31861 taataagctc atttgctatt ttattatatt tattcatttt tctacctcac tttcaataat
    31921 actgcatgaa atggtttcaa acgcactgtt ttatttaata gatttatatc atctaaattt
    31981 tggaatacaa tatcatattt ttcttctact cttatttcta caggtttatc agaaaaatta
    32041 taataacaat caataactac caaatctaat tgccttctat acgcaataat atcatcactt
    32101 tctatatcaa taggttctat tgaaccataa atcaaacaat cagaatactc actatcttgt
    32161 ctcaacttta tcatcttttt ataaaattct aaaatactct ctgaattgtt aatctgactc
    32221 tgtgcattaa tatctttata attttcaata acctttaacc atggtgttgt atctgaaaaa
    32281 cctgcatttt ctttatctgc ccatggaaat ggcgttcttg cattatctcg gcttcttaaa
    32341 ttcacaaatt ctaacgcttc ttcttctgag taactttcat ctattgaacg atagtattgg
    32401 tcaatgctag ataaatcatt aaaatcattt atggtatctc ttttaaaatt tgtcattcct
    32461 aattcctgtc cctgataaat aaatggggtt cctcttaaaa agaaatacat tgctcccaac
    32521 atttttactg catcatcatt cctttcgtat tgcaaaagat actttgttgt agctcttggt
    32581 tggtcatgat tttcaataaa attagctgcc catccatgtt cctgaacata catttgacta
    32641 tctaaaatgc attttcttaa atctggaatt gtccatgaaa ttcttttaaa ccactcacta
    32701 ccagaagcaa catctaagtc agcatgttta aagtcaaaga ccattgaaaa gaaaccatct
    32761 tctccaataa aatcacctag ttggtcatag ctaatacctg ctgcttcagc aacagtcata
    32821 caatcatatt ttttaaacgt attttctttt aattcataaa gcattttttc tattccaggc
    32881 tgatttctaa ctgtttttgt acatttaaca agaccatcaa caccatcact ttctaaactt
    32941 tgaaaactta aattcttttt gataaatgta atagcatcaa ctctaaatcc tgccactccc
    33001 atttgagacc aggtattaat catttggtaa agttcacttc ttaatattgg attttcccaa
    33061 ttaaggtcag gttgtttttt accaaaagaa tgaaaataat attcgtctct attctctacc
    33121 ttttcccaaa cacttccacc aaaaacagac ctccagttat ttggtaaatc gtttcctttt
    33181 ttaaaaatat aataatcatg ataaggactt tctggatttt ttaatgcttc ttgaaaccaa
    33241 ggatgttcat cacttgtatg attaagaact aaatctaata taattttgat tcctctatct
    33301 ttactttctt taattaactc ttttaaatct tccatacttc caaattcact tgcaatatcc
    33361 aaataatcac taatatcata cccattatcg tccataggtg atttaaaaat tggacataac
    33421 cacaatgatg taatacctaa atcttttaaa taatctaaac gagaaataat tccctgtaaa
    33481 tctccaattc catcattatt actatcttga aagcttcttg gataaatttg ataaacgatt
    33541 tctttttgcc accatttctt ttccataaat tactcctttt tatatgatat ttcttctttt
    33601 taattcttta taaattccat tatcgaatat gtcctcacat atagatgtcg ctatatcttt
    33661 aagttgttga tgactatttt tcattgcaat tgtaacgtct gatgcttgaa acatgacaat
    33721 gtcattttga ccatcaccaa aacatatggt ttctttttga gttactccta atctttcttg
    33781 taatctctta attgctttgc ccttatgaaa atctttttga ataatttcat aatactgact
    33841 agaaatatct ctctgtgcta attccatttt atcttgtagt atatctttca cttcgtcaaa
    33901 taccttttca tttgaccata aacaaatttt atgtatatct tgtgacttat actcttcaat
    33961 gttattttca tatgttattt tttcttggat atgttgttta tttatacaag aattagttcc
    34021 ttttaactga ttcattgttt caaatatttc tttggctttt tgattcatga aaactttttc
    34081 ctgactctca atcgaaaaag caacttctct cttttttaat aaacaaacaa cttcctttat
    34141 caatctttga ttaaaagatt gattataaag taattcacca tgatattgaa tgtaattacc
    34201 tcctcctgca atatatccat caactcctaa tgataaaaca tcatcttgta ttgtacccat
    34261 acttcttcca gtacaaataa caacactgca atgattcttt tgacataaac gtatagcatg
    34321 ctttgcagat tctgggattc catatacctc atctctaagc gtaccatcta tatcaagtat
    34381 taataatttg tacaatttca tcttcctttc ttactatcaa aatcataata gcattcaaaa
    34441 aaaaagatat caatattttg atatctttta aaaaatatgt tcatttttag cacaaatttt
    34501 cattttcggg gaatatgttc actttctaaa tacatcttgt atttaatata aagcagttca
    34561 attaaaataa aataaggtgt tgttacatcg tagtccagtt gtttatctac agaaatagat
    34621 atagattgaa tatacaggtt ttcatcacat aatcttgcta aaggattact tatcattttt
    34681 gtaatagaaa ccatataaat tcctttcatt ctcatttctt tagcaaaatc aataattgta
    34741 gatgcatctc cattcaatga aataaagaaa atcatatcat ctgtttttat aaaatgatta
    34801 agtgcctgaa tcatatcata accataaaca tcatatataa ttttccctgt tggtaagaaa
    34861 atccttttca tctctttagc aactctttcc tgagaataac cttctccaaa gacgattata
    34921 cgatttgcct ttttcattct ttcaaacata atcgaacaat ccttcttctc tatatcatct
    34981 atcaccttat tataacaatc cattaattgg tgtttacttt gatttttata ttctacttct
    35041 gtttcattta agcgtataat aactcttaat tcactatatc caggtaattg tagtttttga
    35101 gcaaaacgag aaagtgcact tgtagatata tggtatttgt ctgcaaattc atctatagaa
    35161 agtttaatac aatcttcttt atgattaaga atacactcac agatatactt atcatttgct
    35221 gtaaatgaat tataatattt attgaaaagt ccttcaattt tcattctttt ctccttctat
    35281 actctatgta attcatatga agcaaatcta atagagcata aaatgctcct acgacttcat
    35341 aagatatagc ttgtaatgta tcaagttttt gcgtttcaac atacagatta tactcacaaa
    35401 gtgttgcaat tgtattatta tcaagcctag ttaaagaaat cgtatgtata tgattgttga
    35461 taaattttgc aatttcaatt cctgcttttg tttctccaga caaagaaatg ataataaata
    35521 aatcattttt ttgaaatgat tctctcataa attcaatttc acctatatca aataagtcaa
    35581 taacacattt acctactgaa agaaatattc tctttatttc ttgagctaaa cttttctgtt
    35641 cattacctgt cccataaata taaattgttt ctgcatcata tattatttta caaatatctt
    35701 gaaatgatat tttttgtaat tcattcatta atagtcgata attctcgcaa acatcatgaa
    35761 aattattatc attattaaca aattctagtt gattattttt aagtaaatac tttaaatcag
    35821 agaatgaatc taatccaatt tttctacaaa gccttaataa agtagctcta gaaacattac
    35881 attcatttgc aattttttca cacgaaaaat tacggtattc tctttgacaa atcaatattt
    35941 gtttaataat aattttatca ttttcattta aattatcata attttggtta actaacgatt
    36001 ctaatctcat tttttccact ccctaaatat tattttaata tacattagtt gctttttcta
    36061 gggaagagtt ttaaataata aggataaaat aatcatttga ttttattttt attaaaataa
    36121 aaataacctg ctaaaagcag gcaccaaaaa gtacttatcc tttcgaacat gtactttaga
    36181 tattgctttc ttcggaagct tcatctcttc atactctaaa atatagtttt ttctaactca
    36241 aaagtatttt ccatggtaga aattacttta attcatctgc catttacttt ttatcttatt
    36301 taataattac tattacttga atatttactt ctttaagtaa atttcatagt taacaaagct
    36361 aaaactatta ttatagatgt taaaatacaa aattgtaagt attgttataa atatgcttac
    36421 agctacaaat atacatgata tattaaaaag aagctgtaaa ttattatcat acatacaagc
    36481 aactatgcct ctattaatcc atgttaattt ttattattta atacaaggag ttccatgaga
    36541 catacatatc cattcatatt ttaaattatc caattctctt atagatttca ccatcttttt
    36601 ataatcccaa ttccatggat taggataagg aactatattt ccattcttat ttttgactaa
    36661 atcacctgca aataatacag cttcaaaaat catgcagaca tgccctggag tatgaccagg
    36721 agtatggata atttttatat tcccaatctg catattctct ccataaggtt caacatcctt
    36781 aatgagcctt ctggaaattg cctttccaat aaacttctta aacccaggtc tatccttctc
    36841 tcctataata aaaggtatat cctctacatg agcccatact tttgctcctg ttttttcttt
    36901 caataattta atattagata tatggtcaac atcatgatga gttaataaaa tatgcttaat
    36961 atctgtaagt ttaatgccaa gtgtttttaa ttctttaatt atatttttcc ccataaaagg
    37021 aagacctgtg tctataagaa taatttcttt atcaaacaca ataaaacaat ttgagccacg
    37081 agtactatct aacattaata cattttcttt tatcttcata aataaattcc ccttatttgg
    37141 tattttacct atataattaa ttaataaagt tataaatagt tataatactt gatattaatt
    37201 ttatttttta ttaaagtata ctataggtat acaagtatta tatttacata agtataccat
    37261 cagtatactt ttttatcaat agaaaggaat aatttatatg tcagaattat caaaaagaga
    37321 taaagaaaaa atacaaagag aaaatgagat tattgataag gcagaaaaat tattttgtct
    37381 taatggattt gataatacaa ctatgaatga attagcaaaa gaagttgaat atactaaacg
    37441 caccatatac aagtactttt catgtaaaga agatttattc tttgctgttg tcttaagagg
    37501 atataaaaga ctttgggata atgttaaaat agaaagtgca aaaggcaaaa cagggtttga
    37561 aaaaataaaa ctttcatact ttgcttttca taaattttac tctgtagaac cttctctatt
    37621 atgccttatg ggaatgattg gtattgtaaa ctctgaaaaa tcggatactg atatgctgtt
    37681 taaagaaaag tttttttctt ttaataaatt tatgtttgat gaaatacaag gaatgtttga
    37741 aattggaaaa aatgatagaa gtattaggca tgatattgaa atacctactc ttatgtattc
    37801 atcaatattt acacttacag gattttttaa tttactatct gtaacaggaa aatcatacct
    37861 gaacaacttt aatatagatg aggaaaaatt tattgaaaca actcttgctc ttttaataga
    37921 ttcaattaaa gcataaacct aagtttataa attaaagttt atatacttaa atgataattt
    37981 tttctatctc taatataaaa aatattaaac ataaaactaa taacttagtt aatggaataa
    38041 ctaaattact gaaaggatta aaagtaaatg gctaaaatac ttcttttaga agatgatgat
    38101 acaattacat ttggaataaa aacttccctt gaaaagaaaa atcacactgt atgttgttat
    38161 aatacgattg ctgaagctaa aaaaaatttt gataaaacta ttgatttaat tctgcttgat
    38221 ttaaatctac ctgatggtat tggatacgag ttttgccaat atgttaaaag tatagaagat
    38281 actccagtga tatttttgac agtccgtgat gatgaaaaag acattatacg tggattagat
    38341 atgggtgcag atgactatgt ggttaaaccg tttttgctct cagtacttca gtccagaatt
    38401 aatgcagttc ttagaagaac tcattcaaat actaacaata ctattacatg tgaaaatata
    38461 agcttgaata aggttgaagt caaagcatat ttagataatg ttgaagtacc tttgacagca
    38521 ggagaatata aacttcttct aagtcttatg gaaaataaaa atagagctat gactcgtaca
    38581 aagttactag aaatgctctg ggatgtagat ggtaatttcg taaatgataa cactcttact
    38641 gttacaataa aacgtcttag agaaaaatta aaaaatccac cttgtataaa aacgttaaga
    38701 ggcataggat atagaatgga ggacagctag tgaaaactcc aagaaatatc aacagtacag
    38761 ttgtttttat aatattctgc ttaattgtaa cttttttatt gagtgtaatt ctaacaacta
    38821 taacttcttt taatgaatac aatgtactgt ctaaggctct tggtgcatca tatgagtaca
    38881 atcctaagtc tacagaaagt atactaaaat cactgaaaaa ttctagtgat aaggatttta
    38941 aaacaggaaa tgaaatttta tcaaaacatg gatattctaa aagtacattt tggagtaaaa
    39001 acttttttta ttttctagtg atatcgtttg gtataatttc aacaatggct acagttatat
    39061 atataatcaa acatagaaca aataagcaaa aactgagtag aataaacaat cttactcaat
    39121 acttagaaga agtgaattta ggaaaagagt ctgtactttt acgatgtgaa gatgaatttt
    39181 ctcaccttga agatgagata tataaaacag ttggggaact tcgttgttca aaagaatttg
    39241 ctttaaaaga aagacaaact ctttcagata atcttgcaga tattgctcat caacttaaga
    39301 ctccaattac ttctatgtca cttatggcac aattactttc agaaaattgt ccagatgaag
    39361 aaatagatta tattaacaga cttacaaatc aaatctcaag acttgagaga ctagtttcat
    39421 ctttacttac attatcaaaa ttggatgcaa gtactttaat atttgaaagc aaacttatag
    39481 atgtacattc tcttcttact tatgcaattg agcctataga aggttcttta agagaaaaac
    39541 atcagacatt tactatcgag gcttctcctt cggtagaatt tgaaatcgat attaattgga
    39601 ctttagaagc tcttttaaat attcttaaaa attgtagtga gcatatagaa gatggtggat
    39661 atatagttgc ttattatagt caaaatcctc tatatgttga gattatcata gaagataatg
    39721 gtaaggggtt tgctcaggaa gaacttccat atatttttaa tagattttat cgtggtaaaa
    39781 atgctagtaa ggacagtatt ggtatagggc ttgctctatc aaagtctatt atagaacgtc
    39841 aaaatggtac tctacatgca gaaaattgcc ataatggtgg tgcaagattc ataattaaat
    39901 tttacacata aaatgctgga ttataggtaa aatacctata atccagctat atctatattc
    39961 tatgttatct attgttttag taatatactt ctatttacat ttaaggtttt attaaacaaa
    40021 caacttaact atccctatac ttgtaagtag tcttaaatcg aaacctttaa ataagttcaa
    40081 atagattttg tttatattgt ttcatttttt atagattcta ctatattttc attcttcaac
    40141 tgcttgtatc ctgtcatata tgatgctatt acaataaaaa gtatcaatat agtaaaacct
    40201 attattgtag atataggtgc aaatggtaaa tactctataa aatatatttc atttatacgt
    40261 agaaaagcat acactattcc tatttgcaca ggaatactaa gtagtaatgg tgtaattcct
    40321 aagaataaac cttccaaaat aagcatcttt tttatgcctt ctggagataa tccaacagaa
    40381 cgcaacatag caaactcttg tcgtctactt ctaatatttc ctgacactgt agcaagtaca
    40441 tttgataatc caatcatagc caataaacct gtaataaagc ctactattaa attcatggtc
    40501 tttattccac tagccttttg tttttcactt tctaaaacat cctcaatact ataatctcct
    40561 gaaccatagt ctttattata aatggactct aatttttctc ttactctagg aatgtcctca
    40621 cgattattta ctttaaatac tcctatcagc ctatttgaac gtaacctact tacttcatca
    40681 taatttttag atatttcctg taccatagac attggaacta tttgcattaa tgtatacttt
    40741 gaactagtat ctactatttt aggaagtgtg cttgtaatag ctcccacttt catgttgtaa
    40801 gtataatccc ctttatcttc gtcatatact ttttcattta atttaatgtt atctcctatt
    40861 gaaagattta aataatctat atatacttta tttctacgtg tactacgatt aatatcttcc
    40921 tccttattat atacaattga ggttggattt tttgtattat aaaataactt tgggtctaca
    40981 gaaacttgcc tacaatattc tgtaaaactc ttatcatcaa gcccaattat atttgaaatt
    41041 atacgaaact tgccatcacg ttctatagga gagtattttt tagatgaaac tatactttta
    41101 aatcctccat ttttcgcaag ttcttttgat gcatcttttt cagtcagcca agtggaagca
    41161 gacatttttt gataatatag tgaacttttt acaccttctg tattatctaa tttttcaatg
    41221 aaagcagact ctacaggttc actattttcc aaataaactg ctatatctct ttggtcctta
    41281 taattatcac ttccataaac agcttttgct ccttcttgat ttgcaattat atgcaaaaaa
    41341 catgtaagta ataaaaaaga taatgttaaa gatattgttg cagtacgata agatttttta
    41401 cgagcacgta gtgcgtttga tgcaagttct ccttctattc caaatatctt tcctaatgaa
    41461 tatttatgcg actttttgat tttaacacta tctccttgtc gtattgcttc tataggagat
    41521 atctttgata cttttcgtgc tggtataagt gcagaaatcc agactgttac tattgtaagt
    41581 aaaactgctg gcagaaaagc aggaatacca taagtaaata ccacttctgg aacatcagta
    41641 tgataattaa ctgaattaac ataaactata agcctattac acaataacca tcctaaaaat
    41701 aaacctattg gtaatggtat aattgtcagt aaaaagcctt caaacactac agacctttta
    41761 atttgttttg gtgatgcacc aacactagat aatatcccta actgagtaag tctagcattt
    41821 gcagacagtg aaaacgcgtt gtaaatcacc attacaaaca cggctactgt aaaaattgct
    41881 attgtaagat acataatagg agttgaaaat tttgatatac tactcataga tgctttctgt
    41941 tctggtgaaa agactaacat ctttaaaaga taattactat tgtatttaag attgtatttt
    42001 ccatattcat tagtcttcca tcccaatgat ttagcaagtt ttggaagttc cttatacgtg
    42061 tctcttatat ttttaaatcg caagtacaca gttatactat cattaggttt tatacttgtt
    42121 ttatcaagat atccaagagc tgtatatgca ggtattactg atgaagtaga aacatctacc
    42181 tttcctacta ttgtcaatgt agcctctgaa atttttttaa aactttcccc tttcgatttt
    42241 ggggctatgg gttcaagagg ctttccattt aagattctat atcctattgg gagagtaatt
    42301 ttatcaccaa tttttacact tggattattc tcaaaatatt gttttgataa tgcaatttca
    42361 ttagcattat ttggtcgacg accctctatt atagtatcct tttctggcat agaattccaa
    42421 tactctgatg tagcatttct ataaattata taatctcttt tctcatcatt aattttgcct
    42481 acataccatt gtccttttac cattacatca tcaactgaag aaaaattttc aattaatggt
    42541 aagtcacttc cataagtata gtcaaacaat tcaccatgcc agttaccttc tttctcaatt
    42601 gaaagtctta taaaatctgt ccacatggta tacaacagtc cacacaaaga agacatcatg
    42661 gttgtagtaa gtaatatagc taacattata gctatactac tacgtttatt gcgtcgtaca
    42721 aagtctaagg tgtattcttg aagaatattc atttcttcac caccttttca gagacaatca
    42781 ctccatcttc catagttaca atacgatttg cctctagtgc tattttctca tcatgagtaa
    42841 taagaagtat tgtctgatta aatcgtttat ttgataagtt taacaagtct acaatttctt
    42901 ctgaattttt tctatcaaga ttaccagttg gctcatctgc taataaaata gctggtctat
    42961 agattaaact tctagctata gatacccttt gttgttgtcc acctgaaagt tgacttggaa
    43021 gatggtttaa tctatcagat aatcccaata tagatacaat ctcagagaat ctatcctcat
    43081 ccacctttct tttatcaagt aacatgggta ataatatatt ttttctaaca tcaagggtag
    43141 gtataagatt ataaaattga taaataagac ctacttttct acgtctaaaa actgcaagag
    43201 cttcttcctt taaacttgat atttctgtat cttcaacata aatctttcca gatgtaggtc
    43261 tatctactcc cccaagcaga tgtaacaatg tagatttgcc agaaccagat gctcctacaa
    43321 tggatacaaa atcacctttt tgaactgata aatttacatt attaagggct gtcactctgg
    43381 tttgatttga accatatatt tttgtgagat tttcacattt taatatttcc atatacaatc
    43441 atctccttta tggttaaatt ttagcaacct aaaatgacat tatagtgaca tgaatacaaa
    43501 tataaattac tattaaaaat attgtttagt ttttgcacat tatttaaaat tataatataa
    43561 aacaaaaact atgcaatata ttttatttat acttttaata tattacatag tctttaaaag
    43621 gtattaactt taaatctata ggtattcaat ttaataatca atagcaagta ttttatgtac
    43681 taaaggagtt ttgctctata tagactcaat ttagtaaaat tatttaataa atattacaga
    43741 ctataggtaa ataatattta caaataaaat taagtttatt cccttacact ataatatttc
    43801 ttaattatat taattgcaat ttcctttacc tttggccctg taatttcttt attggaatca
    43861 tctgatttaa tagcaaaata ataggtgtca ccttcacgct ctagcatacc aacaaaccat
    43921 gcatccacac gtttattttt ttcatcaaat cctgttccag tttttccata tacatttatg
    43981 tttttatcat ttatatctat tttcataata tctcttaaaa tattaatatg ctctttttta
    44041 aagtttgtat ctccctcaaa tatttttgcc attgtttgca cttgttcttt tggagatatt
    44101 tgtaatgaag attctaacca aaatccattt aaatgtccct ttccattttt taaatcgcct
    44161 tcccattcgc taatatcgca attcccatac tttaaatcat ctaaaatgtt ttggacagat
    44221 ttagcatcaa ctttatctat caattttttg taataccaaa cacaagactc cttaaatgcc
    44281 tcttctaaac taagattttt attccaattt ttatttggat actctgtacc atcatatccc
    44341 ataactgatt cttttgagtt tattacccct ttttctaaac caattaaagt tgaaactatt
    44401 ttaaaagtag aacatggtga ccttcttgtt tcaattaatt ctttgttata tatattatat
    44461 tctttatttt tagtattata aaaaatagct cctccactaa taccttcaaa acaatcacta
    44521 tagtcaacca tattaatttt ttcttttttg tttttatcat tgttttcaat tttggattta
    44581 tttaattcag acttatttaa ttcagatttt atataattct tatcagtttt ttgatttata
    44641 tcgttatgtt ttttccctac ataatacatt accataacta caccaaccaa taagatagct
    44701 atccaaataa aattcttttt tcttttcata atttatatca tctcccatat ttaaatttat
    44761 aacctactat taaaatagta gacattattt gtaatatact ccaatctagg ttctacttat
    44821 aagaaacaag actaaatgaa tagctgtatc tcttatattt tcttcaccta gtacaattat
    44881 gttgattaaa cctattgcga agataattag gtaactatta ataacatcct gtcctccttt
    44941 taatttgtga tataataatt gattccacat ttaaaactta ctattgtaat atttaaatat
    45001 tacaatagta agttttaaat gtcaagttag tttaggaaag ttattttaat tgtataattg
    45061 ttattacatt tataaaatat ggcatgttta aaattatttt gctattggga ggattaagat
    45121 aagcagtatt ataaaagcta taaattataa aatttaatat ataatttata gcttttactt
    45181 ttacaaatat tgtttttatt gatttattaa tgaattttat tgacaggtta tatttatata
    45241 agtaaacact tacataataa gtatataatc tacatatcta taagttgagt caattcacaa
    45301 gtatatgtca acttaagttt atgcatagct cgtgtacagg caatatataa caaactgcgg
    45361 tcataatcac tataatatgt tttattattt actgaaggta caataacttc atcaaactct
    45421 aaaccttttg acattttaat agaagttatg gatactcctt ttgtaaagct agaactttca
    45481 gaagatatta agtgaacact atattcttct cttaacgcat catatacagc tttagcgtca
    45541 ttatctgtct ttaatataat accaagagtc gcattatcac tctttttaaa ttcttcaatt
    45601 tctattttta tcttatttat ttcatcttgc tcgttattac attttaataa agctggttct
    45661 tcaccatgtc gttcaatagg ctctaatgaa gatatgtctt gaatcttttt ggcgaaatta
    45721 ataatctcaa aagtagaacg gtaactcttg ttcaacataa ctaattcccc atcattatat
    45781 agctgtttca tatcatctag tgtatgagta tgattaggat taaccaattg tccaaaatct
    45841 ccaagaatag tctttttaca cttaaaaagt aagtttatta cagcatattg aataggtgta
    45901 taatcctgca tttcatcaat aacaatatgc cttataatct tatcttcttg tataccttca
    45961 tatgcagcat gaatatatat aaatgggtat acatctgacc attcaagtgt tttcttttct
    46021 accatcacaa acatgtttga tatattcatt tgtttaaaga aatccttata tagtgtaaga
    46081 gtatttttta ttgtcaacat tccattcaaa cttttaagta tactttttac ctttggtaaa
    46141 tcttcttcca taatattatc tgattcaaat ttataatgaa tgtcttcagc tacattctct
    46201 aatctcttct taactggata tctgttatat gcctcaaatc tactctgtat ccagtcactt
    46261 ttagctgtaa aacttccaaa agtgtagtct tttggaataa aaatcttatt tggcatttgt
    46321 tttatataat catcaataag ttttacaaaa tcaagtgtag atttaaaacg cactctttca
    46381 gaccatttag catcatttat ttctaatggg tctttctcac tttcaaaatt aataactcta
    46441 tctaattgta cctctgctat attttcaaaa cttaattcac ataatggttc ttctccaagc
    46501 tcaggaagga cattggaaat atagtctcca aagactttat taggtgatag gataattaca
    46561 ttatttgctg atattttatc tttaaatcga taaagaagaa aagcaattct gtgtaatgct
    46621 atagatgttt tcccagaacc agctacccct tgaataatca gtgtatcagc tttatcattt
    46681 ctaataattt gattttgttc cttttgtatt gttgaaatga ttgacttcat tttttcatct
    46741 gaagtgtgac taagttcttt ttgaagaata tcatcttgta tattaatgga actttctagt
    46801 gcatattcta attttccatt tttaatttta aattgtcgtt ttcttgttat ttctccatcc
    46861 acccatccta ttggagcatc atatccagct tttccgattt cataatcata aaacatactg
    46921 gcaattggag aacgccagtc aagtattata agctcatctt cataatcaaa tgcaaatcta
    46981 ccaatataat acttagattc atcatccata tctttcagcc taaaatctat tctagcaaag
    47041 tatggagaat ctttgatttt attaatctta tctcgaactt ttaccataaa agccccatag
    47101 ttatctattt gttttagtcc ttgttcattt tgaaacattt catgtgggtc tatttcacca
    47161 cgatttttta ccatatacat tttagcgtcc atataatcct tatcaagctt gtcaacaaga
    47221 ttttcagctt tcttaaaagc attgtctagc ttgttattta tctctattag atgtgcaatc
    47281 tcatctggaa aaaaagttaa taactctgca tcatattcac acatattatg tttagaatta
    47341 gatgcaataa tatcgcaatt tactacttgt ttattttcag acatttaaat cctcctttgt
    47401 taattaagta cttacactga atcattatac ttaattgtgt tttggagttt ttaatcattc
    47461 ttgctattta acttaaagga agaataaatt tttgagtagg atatccaaat tccacaagca
    47521 actctgcttc tgcaaagccc aacttcttta tcatatctct atgtcctgta tcagctttgt
    47581 caccctctcg aaaggtagta attgaaatat ctgtatctat caagaaatct tcaataactt
    47641 tcttcaaaaa cacttgtgca atgtctgaat tacgatactg tggatgtatt ccaaaaaaat
    47701 caatacttct agtttctcta ttaaacacca tatttgcaat agcgacatta ttaagtttta
    47761 atattaaagc tctttcttct aaaatatact gttctaattg atatatatat tcttcctctt
    47821 gcaaatttgg aaatccatct atgactaatc tcactaaatt catccataat ggtatgtcag
    47881 acatacttgc aagtttaatt tctttttcca actctagtac attctttgaa aataggttat
    47941 cttttttcaa aacaaatctt agctgcaaag gataaaattc ttgttctttc ctatatttat
    48001 ttggagattt tttatacata gctttaaata tagaagtgaa tgcctgttga ctttcatatc
    48061 cagctatcaa tgcaatttca ataattggtt tctttgaaaa taccaataat tttgctgctt
    48121 ctgtcaactt tctccgcttt atgtaatcat gcattgttag accaacagaa gttgtgaaag
    48181 ttctatgcag gtgatatttt gagtaatgaa cagcattagc aactatatct aaatccagct
    48241 tttctgataa atgctcctct atatagtcaa tagcagttat gacattaatt actttgtaag
    48301 acattgcagc ttccctcctt ttatccatgc aacattatat caattattac ttagttatat
    48361 ttaatgaatc ttgctatttt ataaacaaat ttgttgttta agttttcaat tcataaattt
    48421 aatatattac tttttacttt ctgattaaag actctaatcc tttaattttc aataattttt
    48481 catttagtaa atctaaaaag ttatttatta ttttcttctt attagattcc ttttagattc
    48541 cttaattaaa tgataaatat ttatattata cgactaaaaa cagcttttta caattattta
    48601 atatgattac aaacttaccc tatcttaaag tttaatgggg tcctgttatg aatcttttta
    48661 ttttaattta agctcttcat cagtttgttt tatatattga tgtatttgat ttcatacaaa
    48721 aaagagtgct tcatgaacta aaaagttcat ttttaaacac tctcttttat gtaaataaat
    48781 ttctattcta ttttgaaata ttataatttg acttataatc tgttaatacc aaaaataata
    48841 aattgtacgt ctaagaatag attctaatta gttgctcagt agtaaaatct gtttttaact
    48901 aatcctgctt tgtatgttga acatattcta taattgtacc atctggatgt ctcaatgtca
    48961 tattatatcc tgtaggaact tttttcttat ctcttactac aactgctcca ttatccaata
    49021 gataacttct ccattcatca acagaatcaa ccataaaagt agattttgtt tctataaatg
    49081 gtttaagagc atcatcagaa ccagataata gtaaaacatt tcctatttgc gctaattcca
    49141 acccaacttc tttataggaa aaacgcaaag aacatttttc ttttaaaaga ttctcataaa
    49201 aaggtatggc tttttctata tcttgaatat aaaaacgtgt taatatatca tatattttca
    49261 tattttcccc ctatatatct atataatatt acctctaaat tataccactc tacaaattat
    49321 ataacaataa attaagcata gccttttgag catcttaagt agaccttaac aatatattgg
    49381 ggttacatta gaatacataa attaaatcac cttgatatta tttaggataa aatttatgta
    49441 gtagcagtaa atgttcttct aattatcaac taacaaacga taatctttaa ctttctatat
    49501 aatgggtaac atcattttcg taagatattc actagctgga cgattgatat catttaaata
    49561 ctggtaatat atatcgccat gaagtttata tccattgcta tttgcccatg aaaataagtc
    49621 ttctaaagta gggtcttgta attcataagg tcctaaatca attgcagtta ttattttctg
    49681 tgcaggaaca atcttttgta gaatctcatt tttcccatct atataagtgg ctacagaaaa
    49741 ccctacttca acatccaatt ttactaaatc catgttatga aaacatacaa tcggtgctcc
    49801 tgaagataaa attcctctct cctccagata tttagaaatt ttttcaaaac tttgttttga
    49861 aaactctgaa aattctacca taaagtcaat tgtttttcgt attgccaaaa aacagtactc
    49921 agattgttca gctattgtta tattggatat tctagtcatt ttattcctcc attactttat
    49981 tttcatttct aatcttttta taccaaatta tacgaaaatt cactgtgtaa ctaattattt
    50041 catatgaata taaaacataa cctccttcca tttcttatat cgaaagtata gcaaaaataa
    50101 tctcatcatt cttgtcacac agtgctctta taatcagaac atacttaaaa gacttgccta
    50161 atttttaggc aagtctaaaa gaaatctttt tctataaaaa atttatacaa acaattaaaa
    50221 tatcaaaata tagactaata taaaactata aatttactaa tctgaacctc ccatggctaa
    50281 agtcacaaga ttactgattt atagaatttc gcacactaaa atatgtctta ctaattcccc
    50341 acaggctacc cccctagttc ctacgttctt acataagtta tctattatca aacatcaaaa
    50401 tttaaacaag tttcaggttc atcttctatt cttgctattt taaacttaca tgcaattaat
    50461 actaaagata ctattggatt tataatattt aataaagcgt atggaccata tgttagtgca
    50521 gatacaccta atgttgctgt tatatacgcc ccgcatgtat tccatggtac taatggagaa
    50581 gttaaagtcc cactatcttc taaagctctc gacaacatct taggatgtat acctctcttt
    50641 ttatattctt tattatacat tcttcctggt ataactatag atagatattg ttcacctgct
    50701 attatattgg taattgtaca agttaccata gtacataata ctgttccaaa tacacccttt
    50761 gctaatctta gtaaagaaga tgctactact tcaagcatac ctgttttttc taaaatacct
    50821 ccaagagata aagcgcatat tgttaaggat acagtggaca tcatattcat aatcccacct
    50881 ttagataata aagcatctac ctcctgtatt tgtgttgacg aaacatatcc attttgtgct
    50941 gcatctaata tagtattcat agattctcct tgaaaaatta ctgcaaacaa tactcccaat
    51001 acagcaccta ctataagccc tggtatagca ggaactttaa atacaactaa tccaattact
    51061 attgctggag ctaataataa tactggtgat aaagtattaa atgtagaatc taatgtagac
    51121 ctaattaatt ctatttgttt tatatctagt gcttgacctg aatacttcat tccaattaca
    51181 ccataaatta ctaaacaaat taataatgat ggtatagtcg aatatagcat atattttata
    51241 tgtgtaaaca aatctgttcc tgccattgct ggagctaagt tagtcgtttc agataaaggt
    51301 gatagtttat ctccaaagta agctccagat attatagaac ctacgattaa tccaattggc
    51361 atacctaaac tttgaccaat tcctaaaaga gctactccta ctgtacccat tgtgctccaa
    51421 gatgaacctg tcgcaagaga tactattgca cagactaatg ttgatgctac taaaaaaata
    51481 tttggtgata aaatttttag tccccagtaa atcatacatg gaactactcc acttactatc
    51541 caagttccta taagtacgcc tattataatt atgattaaga ttgcttgcat tgccatcttt
    51601 atactattaa acatacttaa ttctaactct ttccatttaa atccaagtct atatacagcc
    51661 acaagtcctg ctactgctgc tgctcctatt agtggtacat gaggtgatga accatacact
    51721 aatactccta gacttaaaaa taatatcaaa caagtaattg gtatcattgc atcaaacaga
    51781 cttgcttttc tacattctcg ctctttcata aaatagtttc ctcctaatta tttaaacact
    51841 acactataat tttttttgca acatatttgc tcgtactaga tgacatgata cccccataag
    51901 ttaataaaaa ttctaaattg tcacctaatt tataatcata ttttgtgtta cttacatcta
    51961 gtatcatgtg gtctgaactt gcccctaata tttttatatc agtgtctatt ggaattaaag
    52021 agtcaatatt tatatcttgt ttacctatag ctatgattgc cctttttaag attcccttat
    52081 cttcataaac aggtttattt ctaaaggcat caactcctat ttctccaata ggaactgatg
    52141 gtttttcttt acattcaact acttggcata ttaatttaaa tgcatcttga tatgttccat
    52201 ttatattttc accgtatgcc gtttctctac caagtagaat ggactcgcct attctcaaat
    52261 tagtaatacc ttctggcata ttattattta tcaacagatg aatcgaactt gaattacctc
    52321 cagatactat ttctagattt attccaaatt tttcttccat tctttttgct atacttacca
    52381 gtctgcctat attttcccta gatggtataa tagctccata acaggttaag tttgtagcta
    52441 taccaattat ttcaatattt tttaatctta ctatctctct tacattacta aaaaagtctt
    52501 cttcataaaa gtatccttct cgtaaatcgc ctaagtcaaa cataagaact atcttatgaa
    52561 taatattttt actttcacat aattcattta atttctttat tgttcctaat tctgagttaa
    52621 aactaatatc gcaataattg ataacttctt ctaattcact taacattggg attctaatca
    52681 atatcttagg tagatttata tcttgtaaat tttttaagtt ttgtattctt gaatctgcta
    52741 tatggtctat tccttcacta catatttctt ctactatttc tttttgtgca caaaatgatt
    52801 tagtaacaaa agatatctta atatttcttt catgacacat ctgcgaaatt aattttgcat
    52861 tatgctttaa cttttctata tctatttcta acctaggata cataatcttt cctcctcaaa
    52921 attcaaactt tttaacagga gcttaagaga tgcttcttca tattttttag ataaaacacc
    52981 catagatgcc ataatatagt cattatctat taatatcttt gttttttcct ttggaaatag
    53041 taattcatta tttttattgt atttgagcat attatctaat atttcaattc tactagggag
    53101 cctagtaagt gctccccctg taccaactat atatcttact tctgttaaat ctttcccttc
    53161 tgcaattttg acttttccag ttgttccata gatatttctt atttttcctg aatgtcttag
    53221 catagcttta acaacagctt cttttgtcaa cctctcaaca aataatattt cttcttttga
    53281 ttttggtatt ggaggataat tctctattac tgcatcaata tctatagata gttcactttg
    53341 taagttttct ttacctataa cttctactat attcttcata tttacatata cacctaaatc
    53401 cccctcaaca cttctctttg cagtaggttc aggattaacc aaaattttat taatatagtc
    53461 acttccatct gtaacagaat gtacatcagt agttgctcca cctacatcca gagttaataa
    53521 atctccaata tttttatata aaagtttaga agcttccatt acagctcctg gggttggagt
    53581 aatattttca ttaaccattt ctttaatgta tttcattcct ggtgctgtag ttatgtgttc
    53641 ttcaaataca ctttgaatga ttcttcttgt aggttctata ttcaataaat ctattttagg
    53701 gtatacattt tcagttatat aaagcttata attagtatct tcaaatatta accttatttc
    53761 ctcttgattt tcaacattac cagcatatat aactggtatg cctagattca tagaagctat
    53821 catttctgca ttataaatag ctgtatctct ttctccataa tcgactccac cagctattaa
    53881 aattatgttt gggtttattt cttttatttt atttaaatca gttcttttaa ttctacctga
    53941 tgttatttga cgaataacag ctccagcccc taaagctgct tctttagctg cttttactgt
    54001 catatcatag actaatccat gaacagtcat ttttaatcca ccagctgcac tagaagttgc
    54061 aaacatatca ttatactcta tatcatctac agataattta ttagctaaat ctttaatagc
    54121 acctgataag ccatttctta catcgccacc ttcaaacact gttgttggag cttgaccttg
    54181 acccaaaaat ataggattgt tagtattaat atcgtggaaa gcatttacca ctgtagtagt
    54241 acttccaatt tcagctacca acacatctat ttttaaagaa actttgctat tttccattat
    54301 ttattactca tttctcttct tttttcaact aagaaagtgg ctacatgtat gcctttgctg
    54361 tttcttccaa atccagcatc tatgccttgt tcaacagcta tttcaggtgt tacttgtgtt
    54421 cctccacacg caatcattac tttatctctt ataccttttt ctacacaata atcgtgtaat
    54481 tttttcatgt ttttatagtg aatatcatca tgacttatta ttgtagatgc aagtattgca
    54541 tctgcattca gttcaatcgc tgcatctacc aatttttcta caggtacaga agtccctaga
    54601 tagtggcatt ctatgccata tttttcaata cctccatgtt ttatatctat tatttctctt
    54661 aaaccaactg aatgttcatc ttctccaacc gtagctgaaa ctattttcat aggtttttct
    54721 tctatatctg ctcttatttc ttcatcagtt agtaccttag gttcttctgg tattactaaa
    54781 ttgtttaaat ctatatcaaa cggaactctt cctttcactt ctattctagt cccttcagat
    54841 tcatgcataa cttctctact tatgacctca atttcttgta agttcatttt tttgacaaat
    54901 tccaaagctg caaactctgc tgttctttta tcagtaggaa gcatcattgt tatcattaca
    54961 attccatctg cacaccattc catttcaggc ttaattttag ttccatttct gtactcatat
    55021 gattctttta gtctattttc tacattatca aaatcgtcaa gctcatcaat atatattatt
    55081 ttgtctggat tttcaaatgt acatccatct attaacattg atggattatc tatagcattt
    55141 tcatcatatt gagctacatt attgtatcca aagtgagcag ttacaggtgc taaataatct
    55201 tcttctcttt cataaacagt accttcacca actccacctt ttatttttct agatattcca
    55261 tcaccatttc tttctggata atttccagaa tcaacaaaaa atccttgttc cacagattca
    55321 aaatatccac caacttcaga tatttcttcc atatataata cagctctttc tttaagttct
    55381 cttgctttgt ctcttaattc accgacatct ttaagttcta tcatatccat aagcccatcc
    55441 ataccaacta aagcttgctt tgctgtatca catgcttcta tattgtatat atgccaaggt
    55501 acatttctac cttcatcagg tgttatagtt gattgtatgt cagctctagt taatactgat
    55561 gttaataggt ttaatacatg agtaactgtt gcttctctag ttgatgattc catatattta
    55621 gtattcattt gagctctcat cttataatca ctaaataact ctctaagtgc aacagcgtaa
    55681 ggtaagtcta tttttaaaca tggtgctgga ggtgctgttg gtggaactgt tgataagcat
    55741 atattacttt tatctatacc tattttttct gagaatatag agtttaaagc gtgttgaacc
    55801 ataagttcag gcattacctt ccatgcttct ctagcagtag cattagcatt atgtgctcca
    55861 tcaatttgag ctatattggc aaaagccatt attttctttg cctcacaagc atctacaaaa
    55921 gaccttacca tgtttatatt cctatacaga acattatatt gtgggtcttg atgtgctcca
    55981 ttgactcctt cctcagcaaa cattactgct acttcaggac cagcaacacc acttacatat
    56041 gaatggtaat taataggtct accaacttct tcttctataa aatcaagagc cttcctttga
    56101 gctcttactt gttttcttgt tattggaact ccacctatac cttgtggagt tccttctata
    56161 agcccatcaa aatgtgattg tccagcagtt ctgataacca ttagatggtc agctccatga
    56221 tgagctgcca ttctcattct tcttatatca tcctcaaatc taccagaagc tatttcagta
    56281 gtaataactg gacttggttg agggtctata ttattgaaat acttagatga tggtagccct
    56341 acactcttct ttaaaggttt tgtacagtct ttatatttaa aaggtcccat ttcaagattt
    56401 tccaagtgtt ctctccaaac ccaacctctt cgttttggtt tatatttatc caaatctttt
    56461 aatatatagt ctatatccaa ttttttattt tcctttaaca tgattctacc ccttctctaa
    56521 ataaacatgt aacttcatcc caatattcac ccttaactaa taacaaacct gcttctctaa
    56581 ccgttatatt tttagattta gccaatttat aaactacatg ccctgctcct ttacctataa
    56641 gacctctttc cataacccct tctaaaatag gttttacttc aagagaagaa aatcccattc
    56701 tcaacaagac agacctttct attgatggtg ttgtattctt tttaccaagt tctatcattg
    56761 gttctactat ctgggtagct aaactccaaa acctttcttt taactcatcc tcactcagtt
    56821 cttgaagatg ttttcttcta acttcaaaat catcctctct ttttttcatg aacattcctc
    56881 cattcgtatt gatttaatcg aattttctga atttttattt tatattaaat taaaaaacaa
    56941 taattactat aaattattta atacatcaac aacaaaatct cttgaacttt ttacttcttc
    57001 cattaaaaat tctatatctc gattacttag cttatcaata ttatcaatgt gattattaga
    57061 tatacaattt tttataaatg actttcttat tttattcata tcaatatcaa cacatttcaa
    57121 taattctggt ctttctggta atattaagtt tactcctgca atttcttctc ttggatttcc
    57181 aaattttata tctattccat tttctcttgc aaaggtaagt tgtggacata tatgtttacc
    57241 tgcacccgta tattctgttt cttgtaccac tataacttta tcttcatcta actcttgagc
    57301 taaagagaat gctgctgcta aagatgtatt tcctgctgga cctctttcta taccttctag
    57361 ctgtgccaat aattcagttg tataaaaaac ttctccttgt tttactaata catatctatc
    57421 catatatcta agtggtctag ctgcagacct aggtacatct gacctatcag gccatgtaca
    57481 gtatggtatc ccaaaacctg tatgtcctgt tgtaaatgat tttttattaa attgattatc
    57541 actagccatg tgtaatcctt ttaaatctac acttgctcct actactttag tattaataga
    57601 accagctttt atcaatcctc ttgcagttcc agtaagatta ccaccacctg catttgtaca
    57661 aacaactata tcagggtctt ttttatactt ttctctaaat tggatagcta actcataacc
    57721 taaagtttct acacctgcaa ttccaaatgg tgaatataat gatgcgttaa aatagcctgt
    57781 ttcttctaat aaaactaaga acgtataaaa taactctggt ccaacagtta actgaacaac
    57841 ttctgctcca tatgcctcac attttcgtgc tttttctata atttcaggtt gacctacacc
    57901 attagaatca taacattctt gaactattat acattttaat ccctgcattg ccgcttgtga
    57961 tgctacagct gcaccatagt taccactagt agctgctatt acacctttat atcccatttg
    58021 tttagcatga tatactgcag tagctgctct tcttgcttta aaactaccag atgcattcat
    58081 tgcttcatct tttacaaata ttctagctcc tttaccttct ttagcacatt ttctagctaa
    58141 tttagtcaaa tttttaagct ctattaaagg agtatttcca acagcatact gtgattgaat
    58201 tgcttcaata tcttgtaatg tatatcctgt ttcactcatc attttctcat aatcaaaccc
    58261 tattccctct tgttcaaaag aagaataatc caatccgatt gcatttttca ttatttcgtt
    58321 atttcttccc ataacagctt gataactcat atctttcatt gatgttgaat tattcattat
    58381 atacacctcc aaataatatt tctttagctt ggattcctat ttggagtaac tctggtatac
    58441 atttaccata atcatgagta taatatggat ttattttaag taaattacct tttacaagtc
    58501 tgcctgtaat tgttttaact tctactaagt cgcctataga agcatcactt tgtataaaac
    58561 ctttaaccca catttctaag gatactttct tagtatcctc tggaacttgt ggagctcttt
    58621 cttctggagt caatactata ttgtgtataa taacccaatc attaatttta gcatccattt
    58681 tttcatcccc ttattaattg actattgcct tactaattaa tttactgtta ttttaaatta
    58741 aacattattt taccaattag ctaactgtta tcttactaat tagctagttg ctatcttact
    58801 aattagttat ctgttatctt actaattagc ctttgattct tcttccaatt caacttctat
    58861 ctgatttctt atatctccca ttattgctct aggtactggt atatccaaca tagttttaag
    58921 acctggtcta gcatttatta ttaatggaat agagtttact atcattgcat aagtacctac
    58981 tcctccaggt atttcaggat ttatttgtaa atcaatgttt ggtatacctt ttattgatac
    59041 atagtctcct gttttaatac cttctgcttc tggtattatc tgttgtggat gctccatttc
    59101 aattaaaact tctccattta catatccata tccacattgt ctacaaccag caacatttcc
    59161 agccaatgcc tctccgtact tagattttct atctactgta gtcattattg gctcttttgt
    59221 ttgttctatc ttatctaatt tccaacctaa tccatcagct atcatattta ttgattctac
    59281 aaaacctaca tgacctgcta tagtcttatc ctctacacct tttataaatt cttcccttgt
    59341 tactccaaca ccttgttcct ccataacaga ctttccaaat ggagataaat catttactct
    59401 cttagctttt atactagtaa cttcttcaca agtacctgaa agtgccaata ctagtaaatc
    59461 taatacaaat cctggattta ttcctgttcc aagtatactt actccatttt cctttgcaac
    59521 ttcatccatt tttttagcta aatctgcatc atcagcttgt ggatatgcca tttgttctgc
    59581 tgttgatata acatttattt ttctatttaa taagaaaatt attttatcaa aagccttttt
    59641 agtaaatgaa tcagttgcta acaaaacaac atctacactt ttttctctaa aaacttcttc
    59701 ataattttta ttgataataa cttctggtct ttctcctctt tcaattccta aaacatcata
    59761 catacttttc cctgaagtac ttctactaca aacagatact atttctatac cttctttctt
    59821 tagaatcata ttagccatac ctattcccat agctccaaat ccccatattc ctactcttac
    59881 ttttctcata tatacaccct cctaaaaatt tatatattct caataattag ttaaagcata
    59941 aatcgtgcca actttaaaat taaagtaaat atttattgga acgttgaaac tataattatt
    60001 ttattatgta ttttcataaa taaaaaataa tatttcttat gagaaataaa aaaaagagca
    60061 aaatattttg ctcttttata ataattttgc tcctctattt tgctttttta ttttactttg
    60121 attttgtttt ttatcttgct tatttataat attttgatat tatatttttt tattttatac
    60181 tgtaaatttt gcctattcat acctaaaatt gatgcagctt tagttatatt gtaagatgcc
    60241 ttttctaatg attcatatat atacttttct tctatctcac tgataatctt actaagtgtt
    60301 ttgtcctcca aatcgtttaa agaataattg ttactctctt tattctcttt aagattgtaa
    60361 tagtcgttta gattaatcat acttgtttct atttgtacct catcttccat catactcata
    60421 gtacaataaa ttatgttttc tagctctctt atgttacctt gccaatcgta attttttaaa
    60481 attttaatag cttcatctga aattcctacc acttttttat tcaacttttt attatacttt
    60541 gaaataaatt ttttgcacaa tagaggtatg tcctcttttc tatctctaag aggaggaatt
    60601 tttatatgaa ttatgttaag cctataatat aaatcttttc gcattttatg ctcgtttaaa
    60661 attacctttg gactttcatt tgtcgttgca ataattctta catctatagg tatatcctta
    60721 gttcctccaa cccttcttac ataaccttct tgtaaaaccc ttaatagttt agcctgtaac
    60781 ataataggca tggaatttat ctcatccaat aacaatgtcc ctttgttagc ttgttcaaat
    60841 aagcctggcc tatctattgc tcctgtaaat cctcccttgc tagttccaaa aaggatacct
    60901 tcgaatagtg attccggcaa agctgcacaa ttttgtgcta taaatggata gtttctccta
    60961 ttacttccat agtgaatgga ctggctaaat aactctttac ccgttccagt ttcaccgtat
    61021 ataaatactg aagcatcaga cttgcaagct ttcttagatt tagctattgc ttctttaatc
    61081 aaattacttt cccctaaaat atcatcaaat tcataaccct ttttttgtct actactaact
    61141 ttattgacta aatttttttt ataatttcta tttagtaaat tttctatcgt tgtcatattc
    61201 tttgatatct caagtgcccc tacaaactcg cctttaatat caattggtat tgtagtatta
    61261 attgctgtta tctcttttcc atttttatcc agatatttct gaatattgtc tttgataact
    61321 tccctttttt ccaaaacttc taatagtgta ctcctgttta ttttcatttt gttgactata
    61381 tcaaaaaatg aattggttaa aatatcgtgt ctgttcattt tttccatttt ttgtacagaa
    61441 ttattgtaga ttatagtttt cccgtcttta ttaacaaaat gtaccccttc atcaatattt
    61501 tccaatattt cattcattat tttaaaaaat atctattggt tcaactatat caccccagta
    61561 cctaaatata taaaaaccca aaaaattaat aaaatgttgc tattgtattt atcttatcat
    61621 atattgatga tattttttat gtacattata ttaatatatt tttaagtata tttaaaattt
    61681 tatttatata tctttcatta tggttatata caatatttga attgtcatta aatataccaa
    61741 tagttttata tattattgat tttattaaaa aaagagatat acaaactaat aagttgtaat
    61801 ctcttttaaa ctctaaatta gaattactct aatatataac ttacaatata atccaatgtc
    61861 ctgtttatag taaaaaccac atttaaattt tagattggat gaaaattatt aagattattt
    61921 ataaactcaa attgttactc tcctttttct tattatcttt tgaatgtatt ctttagttaa
    61981 aaagttttac tttctcatat attataaagg aagataattt tttacaaata atccacttaa
    62041 tagcatcctt actttaaacc taaagttcct ctattccaat ttcttttaag tattcataca
    62101 caccattata aaaatttggc tgcattgtaa tatcactctc atcacctatt gggacaaata
    62161 taataaagcc ttgccttgcc cttgtaagaa gaactctata tgcatttttt aagtatagta
    62221 tattatcttc tttattgatg ttctgccatt tagttccatt gaagttatag tattcaaaat
    62281 ggttattctt aaatcttaag ttcccatccc aacagacaat tgtccagtct agctctaaac
    62341 cttggatatc aaactctgtt gcagtttctt ctaaaaaata tgaagctcgt acatcatcct
    62401 taccattaag aaaccagttt gtagcatcaa ttttattttg tacccacact ccatactttc
    62461 gaagccgttt agctccagaa cttgcagtca ttccataacg ctgtgaacct tttgatttat
    62521 ctctcaccca ctttttagct aattccaaat ccctagtaac acatataggg taatcttttt
    62581 taaattgatt atataattcc tttgcagcaa ctttatctac atccaaaaca gctttaacaa
    62641 aggttgatac attttcactt ctaaaagaac gtaacgatac agataagtgc aaatcatcaa
    62701 ttattctata attaacacct tctgttaact catcaaaaga attaccttta gaatattctt
    62761 catcaataat tttatttgat atgtaaacat cccaatcaga ataattattt cttagtgatt
    62821 caaaccaacc tgatattcca tctgactcac ctttatttat ctcttgacct ccaccaatca
    62881 aacaaacaat agtcgcccat cctatatgac gatttaaaat actaataaga aattcaggct
    62941 ctgacatatt aaagtctaat acgccttttt ttcttttcat aaagttagtc aaattaggtt
    63001 catcccacgc acgttgtgct tcatcaaaaa ttgtgactct ttcaataggt ggtgtatcaa
    63061 cagatatagc ttcatctcta aaatgatgaa ttatctgaat aaattctttc gcttttcgaa
    63121 tcgcttcaga ttttcgtatt ccatttctgg ttacatcatc acgagctagt gcttcttgta
    63181 aaacatcaac taatggacca tttccagaaa ggaagactgc atgttcattt tcatctactt
    63241 tttgtcgctc aatggcaata ttaaggccag caagtgtttt acctgctcct ggaactcctg
    63301 tgataaaaca tattgatttt ctgttatgag tcttactata gtctataatt ttatttatag
    63361 ctttagttgt ttgatttaaa tttttagcac ttgcatcatt tcttgaaata tcttcaacat
    63421 tatggcccat atataaagct tgtgcagctt caataattgt tggagttggc atgtataacg
    63481 agtttatcca agtgtctgaa ttaaatgaac ttctattata tgtagtacaa atcttcttta
    63541 tgtattttcc tatattaaac tcattacaac aataagtttc taaaatattt tccttcatca
    63601 ttcttattct ttggtctttt tgaggggctt ttgtacaaat aagtattggt actaaaagtt
    63661 tatcatgact ttctttgtga aaacaattaa ggtcaagggc atagtctgta acttgttcaa
    63721 ttgcatgctt aggataagtg tcttcatcaa ctttaaattc aaggagaaaa acaatgccct
    63781 tgtaaattaa cacattgtca attctactgc ctattcgtgg tattgtatac tcaaataata
    63841 agtgtccatc tttgaaagtt gagagctctc tttttaatat tccaatttcc tttttccatg
    63901 tattcttttg taagtcatca gccgcaaatt gatcattaca cgttatctca ccaaatatag
    63961 taaaaatatc tttgactata aattcattta cactacttga ataatatgct cttttcatac
    64021 atcttccccc tttatatcta atattcattt tatagcctac atctatccta cagtctaaaa
    64081 cttgactcct atactttata aatacactac atagatatgt ttatgtatgg tactttgata
    64141 ataatttttc tttgctaagt acattataaa ctatttagtt aatatgtttt ttccatatat
    64201 gcttattata ttataaaatg gatagcgcat catttaaatc attgattaaa tcttcactat
    64261 tttcaagacc taaacttatt ctaattgtgt atggtgacac atttaatgct ttggcttgtt
    64321 ctaaagtcat ttcatttaat atagctatat ttggagcaaa tactaaactt tcatggcctc
    64381 cccaactcac tcctatttta aataaatcta atttatttac aaatttttta acatcattta
    64441 catcctttgc gtctatttca aaacttaata acgcagtata attaagcaac tgtttctttg
    64501 ctagtttttt ttgattaaaa tatttagata atggatgata taccttagta actgctgaat
    64561 gattatctaa aaattcaact acttccttag catttttggt atgtactgat aatctagcgt
    64621 gtaaagttct caaacctctt ataactaaaa atgcttcaaa tggtgctagt tttgcaccat
    64681 ataaagctaa ttcactccct cttatttctt ctatatcttt tttacttcca ataatacatc
    64741 cacctaccac atctgaatgt ccatttaaat atttagataa agaatgaact tctaaatcaa
    64801 ttcccatctc aatacatctt tgatataatg gtgtagccca agtattatct attactgttt
    64861 ttatattgtg tgtttttgct agtgctacaa ttgcctttat atcttgcatt ttaaatactg
    64921 ctgttgatgg acactctagg tatattaaag ttgtattttg ttttatagca ttttcaaaat
    64981 cttctattct atcaccttca actattgtat tttctatatt tcctttctcc ttcaattcct
    65041 tcgttataaa gttcattgta ggattgtata aattatttga agctattata tggtcaccat
    65101 tttttacaaa atgaagtata gcacttgata tagcacccat tcctgaacca aaggttatac
    65161 ttgcttcagc attagctaat gcagataact ttgcttctaa aatatcatta gtaggatttt
    65221 tagttcttga ataaagatat ccatcttttg aaccttcaaa atatgcttct atatcttcat
    65281 atgtacttct tgcgaatatt gatgattgat atataggtgg gtttacagct ccataatcgc
    65341 catccaaatt ttctcctaca tgattcatta atgtctctat cttatattta tttttatcca
    65401 tgttctaaat ctccttatga aatattttta tatatgaaaa atacatttaa catagcttat
    65461 tttttataag ctatgttagg taataaagtt aaaatattca ttatgatact ttattagatt
    65521 gttttttatc ctttgaattt ttatatgtac ctatccctgt aactgctaag attactgcta
    65581 taattggagt tccccagttc actatagacc aaagtgcgta ttctccaaca ttaactccta
    65641 gtgtctgagt gaaaaatatt gctgctggtg tccaaggaaa taaaacttct aacaatgtac
    65701 ctgtatcttc tgtagttctt gatagtaccc tacgatctat attattctca tcatatttat
    65761 ctccaaatat acctgctgtt acaaaactac atgctatacc atttgcagtc attgctatca
    65821 ttgctattcc tgttaataat gaagaacata ttatagccgt tctagactta acccacccaa
    65881 atatcacatt taccgttgct ggcatagcat caatacttcc aagtactcca acaacaaata
    65941 atatagatgt tgatattggc aataatttac ctaattccca gaagccacct ttttggaaaa
    66001 aacctaatat ataagcttgt ccttctatag gttttgcata ttcatgccaa gttaccatat
    66061 ctagtgagaa tccactgtta agtcctataa gaacatctgc caaagaaaaa ccttgaaaga
    66121 ttactgcaaa tgcaagtgat aaaaatgctg ctattgtcat tactggtatt gcaggttttt
    66181 tcattgctga acctactaat actattaaaa gaggtataaa taaaattata ttgaaattga
    66241 acattcctga taaatctgcc aataatctag ttatttctgg actatttaaa tttgtatttg
    66301 ttgctgggaa tataaaccca caagcaatat atataactaa agctattata gttgctggac
    66361 ctgttgtcca taacatagat gcaacatggt catataaatt aacttttgac gctattgcag
    66421 ctatatttgt tgtatctgat aggggtgaca ttttatcacc aaagtaagct ccacctacta
    66481 tagcacctgc tataatagca ttgtttgctc ctattgcatt acctaccccc atcattacaa
    66541 ctcctatagt tgctgctgat ccccaggaag ttcctgtaaa tgaagaaaac aatgctgaca
    66601 atattaatgc tgtagcatat acaaatcttg gatttatcaa tttaactcca taatatacta
    66661 acataggcat taatccactc ataataaatc ctgcaataag tggacctatt actaataata
    66721 ttattaatcc tggtaaagct ccttttacac catctaatcc actttcaaat acttcttccc
    66781 acgttttatt tgttgtaacc actataaata gcgatattat tgatgctgaa ataaacatta
    66841 ttgactctat tggcaaacta tattccgact tattgttaat cattggaagt aatagcccac
    66901 aaaataaaac tgccataaac aaaactatag atatagcctg cttttgaatt gtaacttctc
    66961 tcttcattta ttatttcctc ccacttttat ttactcatta attcaatttt taataacgtt
    67021 ttcccttatc taacaataaa atttactatc ttatatttat attcaacaat atatttatat
    67081 atataaatat attgttgaat attttattat aaactccagt ttattcttaa actattttct
    67141 taagtgaatt tactttctat atcttttaat cacctcctct ctcatagtgt tttattaatt
    67201 gtacataata aattatcata gctttgttta tcttttatct tatctagtac aaataatcct
    67261 ctgatattga aaccttaaaa ttttttgata agtctctaaa gttatctcct gttattgttt
    67321 gttttttccc tcccatagat attactttta ctaatatctc agccgatttt tctactgtat
    67381 ccataagacc aaatgttaag tccaaagttt ctcctgagca gaacgttcca tgatgagccc
    67441 agattactat gttatgtttt tccattagat tttgtgtagc ttttgctatc tctataccac
    67501 ctggcaccat ccaaggtacg attccaattc cttctggaaa tacaactgga cattctgtag
    67561 ccatctccca taattctctt gtaaatactt taccctcaag aggcagtata aaagttaatg
    67621 ctatgagatt agttgtatgt gaatgcatta ttactctatg taatccattt gttttgtctt
    67681 tttttataga atgactcatt aagtgagatg gaaattcact tgttggttta gccttatcta
    67741 atccccaaac tattgcataa ttttcacctt tttcatctat tttaacaatt cctacatttt
    67801 gaacagtatt tatagaaata tttctcatga atttgccact tcctgtaact aagaaatatt
    67861 cattagctaa attttcgact gttacaccaa ttggaatata ttctatttct tctgttataa
    67921 attcttttat tccagatatt tcttcaggtg ttaatctata cgttatattc cccccattac
    67981 gctcatgcca tccctttaac caagcatcat aagttatttt cataaaatct ttgataaagt
    68041 tcatttccat tatagacata tacccttacc tactttctat ttaataattc tgttaattcg
    68101 tactctttta ctacttctat ccaatcttct ttaacagcaa cattattaat tttacaataa
    68161 tagttccata tgtctcccat tggatatgtt ttgaactctt ccattatagc caatcttttt
    68221 gtaaaatcgc cttcgtcttg taattttctt aattcttcat gaggcattaa catagctgat
    68281 aacaatgctt ttatcatatt tctagttcca attacccatg ctgctatacg atttatactt
    68341 gcatcaaaga agtctagtcc tattattact ttatccaaag catcatttct tactatttcc
    68401 ttggctattt cttttagttc atcatctaat ataactacat ggtcactatc ccaacgcact
    68461 ggacgactta catgaagtgc aactttatct gaaaataata gcattgatga taatttatct
    68521 gaaacaagtt ctgtaggatg atagtgccct gtatctaata atgaaattat gttgttttta
    68581 ctagcaaaat ttaagtaaaa ctcatttgac ccaactgtat aagattctac acctaatcca
    68641 aaaacttttg attcgacaca atctaaatta tattctctgt ttatctctac ctttaatatt
    68701 tcttctagtg attcctttaa gcgtcttcta ggacctaatc tatcacttgg tatatctttg
    68761 tatccatctg gtatccatat gtttgttaaa caagtctgac caagctcctt tccaaagtat
    68821 tcgcctattt ttctagaagc tatgcaatgc tttatccaaa aatcacgtat ttttttatct
    68881 gggtgtgaca atgttaaccc atcacttgat tttggatgag agaatattgt tgggttaaaa
    68941 tctaatccca atcctctttc tttagcccat tttacccaat tttcaaaata ctctggtttt
    69001 agctcatctc tatccacaaa gcttccacca gtttctgcat atatagcatg taagttaact
    69061 ttatgtttcc ctggtattaa acttaaagcc ttatccaaat ctcgtcttaa ctcctgagga
    69121 tttctagcct ttccaggata atttcctgta gatgcaattc ctcctgatag tctttgttga
    69181 tttccttcaa accctgttac atcatcacct tgccaacaat gaatagatat tttaacttta
    69241 gataaaactc ttaatacttc ctctacattt attccccatt tttcatattc ttttttagct
    69301 acttcatacc tttgctttaa ttccatcact tatctccttt ttcagattaa ttatattgaa
    69361 ttatatcaaa tgaatttctt attatatctc tcgcctgttc taaatcattt agctcattct
    69421 tagcaattaa ttgacatact atattaccta atgctgtagc ttcaacaggt cctgctaata
    69481 cctttttacc actttctttt gctataagct catttaacag ttcattttga catcctccac
    69541 caaatacact tatagtttct aatttttctc ctatgatttc ttctatttca tttatagatt
    69601 tactataact ttttgctaaa ctgttaaaaa tacaatatgc tacttctcca actgtttgtg
    69661 gttctgtttg attagtttct atacagtatt ttattatttc ttgtaccata ttttcaggat
    69721 ttaaaaatct atcatcattt acatctacta ttgatttaaa tccttctgat agtcttgcat
    69781 gctctactag ttctgtaaaa gagtgcttac tgtcataaca ctttctagct tcttgtatca
    69841 tccataaacc cattatattt tttaaaaatc tatatctata ttcatatcca ccttcattag
    69901 taaaattata atctaaagcc tctaatttgc actttggtct ttctaactct actcctaata
    69961 aagaccatgt tcctgaactc aataaaatgc ttctattttt tacaggagta gacatgaaag
    70021 ctgaacctgt atcatgagta actggtaaaa tgacttctaa atcacatcct aactcttcta
    70081 ctaattcttt ctttaaacta cctagtattg ttttgggagt ttttatttta gcaaataaca
    70141 tcttgtcaaa tccaagttta tttattattt cttcatccca attatttgtt gttgtattta
    70201 ctaattgtgt agttgttgca tttgtatatt ctgtaacttt tttcccagtt aataaaaagt
    70261 taaaataatc aggaatcatt agaaagcttt ttgccttttc taataaatct ggctgttgat
    70321 tttttattgc taataattga tatatagtat taaacttttg aaattgtatt cccgttttta
    70381 aatatagttc ctttttatca attattttaa aggcttcttc cataattcca tcagttctat
    70441 tatctctgta tgatacacag ttacctaata tattgtcttt ttcatcaagt aacacaaaat
    70501 ctacagccca tgtgtctata gccacactta ctggaatttt atttattttt atacattttt
    70561 ttatcccatt ttttatttca gaaaatagct ttgatatatc ccaacaaaaa tgaccatctt
    70621 ttttaatcaa attattctta aatctatata cttcttctat ttccaatttt ccattattta
    70681 tataagagat aatatgtctt ccactagatg cccctatatc aattgctaaa tagtatctca
    70741 agacttttcc tccttagatt tatttattaa ttgaattata caagatgtta gtatattcat
    70801 ttaatatcta aatttgtcat atttattaac ctaatttgca atataacttt attctcaata
    70861 ataattttca aaatataata tcttcagagc tattaaaatg gtttatttga taataaaaaa
    70921 gaatctattt tatagattct aattttacta ttgactattt tttatatttt ttttgtattc
    70981 ttttggtgta ataccatact tatttttaaa tattttataa aaataagtta aattttcata
    71041 acctacattt tctataattt cagctattga taaattagta gatactaata attcacatgc
    71101 tttacttaac cttttttctt gcactaaatc tttaaaagta tatccaagat gtttttttac
    71161 tagtttactt attttataat caccttgatt caaattactt gcaatttcag ataaactacc
    71221 tttcttgtag tccttatcaa tatattttag tatttctata atcatcatct tttcataatt
    71281 atctactgca tgattttcta catcttcaga atttttaact aattctacta ataataatcc
    71341 tactaataat ttaatcttta ccttattaac cacacttggt tcatacaatt ctattataat
    71401 tttttctatt atatcttgaa tctcttcttt ctcagatact ttaaaatata tatattctcc
    71461 aagattataa ttagtatata atgtagtcat taaaaagttc attattttat tatcattttc
    71521 caacaaagat ataatataat caaaaaactc tggttttatt ataaaattaa ttattatatc
    71581 ttcttcgtca ctagcttcta tttcatgaat aacatgctga tttaaaaata ttaattctcc
    71641 ttgttttaaa ttaattttat attcatctat agtttgtact aactttcctc tataaacata
    71701 attaaattct atataattat gcttatgttt tggaaattgt gcaaatcttg tatgttttct
    71761 tatatgtatc aactcatcta tattcaataa tttgttgcta tctattataa attgagaatt
    71821 atcagtataa atacttttat ctattatata atttccttct aatatatttt tttcttcttc
    71881 tgttatttcc ctcaacttat catgaatata ttgtctcatg agctacctcc ttagttagtt
    71941 caactactag ttgtttcaat ttaaaattat ttttagcatt aaatatataa taattatcac
    72001 atctttttcc tttgtgtata gttcctgata aaaaattata tattaactca ttagatgaaa
    72061 ctctataaag ttatgtttat gtttgggtat atctataaat ctacgatgtt tagatatcat
    72121 aatgtcttca tctaaagaaa gtatattttt atctgttagt actatagttc catttatttc
    72181 ttcccaacat aaaatagtat gcaatataga cactattttt ttattatcta gtttttttac
    72241 attcttagta actatgtatt ctaagatgta cctttctgct tgtgtttttt gtttaagtat
    72301 atcctctagc gtttcatctt tcatttatat ccccccagat ttagctatac tttattacag
    72361 ttttaaatta tattacaaat attctttatc taattgtatc atattagttt ttgacagtaa
    72421 taatgttaaa ttatgacatt taaaaatacc tttttttgtt ttaaaataca tttataggta
    72481 aatacttaaa atttaggagg tattttttta tgaatacagt acgcaaatgt ttcaagatga
    72541 agctttttaa aggatttgaa aatgaataca agaaacgtca tgatgaatta tgatctgaga
    72601 tgatagatat gattcatgaa tatggtggta gtaactattc tatttttcta gatgaagaaa
    72661 ctaattattt atatggatat atagaactta aagatgccaa actatgggat aaaagttcag
    72721 agacagcaat ctgcaaaaaa tggtggaatt atatgtctga tataatggaa actaatgagg
    72781 ataatagccc tgtatctata gaacttaaat ctatgtttta tttaaaataa ggacaaaaat
    72841 tattataaat cacaaaatgg ggatatatca aaataaaaat ttgaattatc tcctttttgt
    72901 ataaaaaaga taagtgattc ctaaaaacct ctagtctatg tgataattgt tctgtgaaaa
    72961 actaaaaaca tatttcgatt atagtagcta aagatgttat aaacaagtgg tatttctatt
    73021 agacattgaa acaattattc ccaaagatga ttcagtaaga ctacttaact taactttaga
    73081 ataattgata tatcttgtgt tgtttatatt aaatttttaa tttaagtaat agtatatgta
    73141 atctttagtc atcttcttac cagtttttta tccacttttc taatgaagtt attttttcat
    73201 atgataattc ctcttgaaat aatgatacta aaagactttt tataaaatta taacttaaaa
    73261 gtttatgtat ttttttgata tgaatttata gtacttatct tctttaattg agattgtgta
    73321 tatttaacta aacattacaa caataattct atgaaatcaa atcaattatt tacatatttt
    73381 tttagaacaa taataagtat atattcacaa aattttgtgt taatattttt agtttgtgat
    73441 ataataaaag caaggaaaca tattttactt aactttgagt gatgtttcct tcaacaaatt
    73501 attttgaaga tttacttttc tggaacttta tattaagttc ccagccactc ttagttggtc
    73561 gctcagagtg gctctttaat ttatcgtaaa tgtaactggc tataacacca gttataatac
    73621 tcatcattag attttccata gttttcacct cctctcataa gaaagtgaag aaacttccat
    73681 ggaaacacca ctcatagctt tttcaaatat ttattccttg ccatattaat tatatcataa
    73741 atattggaaa cataaaattt taatacttat cgtctttatt attatttttt ataattaata
    73801 attttctttt taataataca taatataaat ttatatttct tcaataaaaa agacaatctt
    73861 aattaattgt cttttttaat atatatttgg ctaatacatt attttacaca aacattacaa
    73921 gggtctattt taccttgtga cttagcttgt tttaatgtta ctttatttat tgttttactt
    73981 ctttttagtg tagaacaatt ttttgttaga tgatatgatt ttccattagg agttacatat
    74041 actgtacttt tatcagttaa tccaggatta ttagagctag gctcattact tggtttgttc
    74101 gtattatttg aattagtatc ttttacaata cctgtatttg aatccccaac attattagtt
    74161 atatttaaac attgttttat aacaacatca tcaatatttc caatagcagt tattttactt
    74221 gcatttttta atatactctt attacttcca tttccaacta acactatagg tgttttttgt
    74281 gcaattgtag aaccaactaa agaataaact aaatcagttc cacttgctat gtaaaattct
    74341 tttgagccat tataaaattt atttattatt tgtttatttg tatcgtatct atctactcca
    74401 cctattcttg ttgctttagt ttcatttatt aacttatcac tcatactgac ttttccacca
    74461 attgcataag tttctaatcc atctgtagca aaacttgtag tatttccatc agttaatact
    74521 attggagatt tatctctaac tgctatagaa gcaacactca tagcatctgg ttcgccttta
    74581 aaagcattag ttaatattac ttttttaacc gtacttactc ttcctatttc ttttgcaact
    74641 ttatgacttg tatctattct atcagttcca cttattctat ttatgcttat ttttttatca
    74701 cttaatattt tctgaactga tgctcctatc gaattttttc ctccaattag atatacttct
    74761 tttacctttt ctaatctttt taatgtttct gaagggattg tatctttctt agttaacaat
    74821 attggggcat ttttagctcc tgacaatcca cttgctgaca atccatcaga taatccattt
    74881 tcagaattaa taagtattgc aatatcataa ttttgtttat ctgctattaa acctgctgtt
    74941 tcatacttat ttgtaccttt tattgaatta atagaactaa gagcgtttga tgttggacaa
    75001 ctagcaatca ataatgaaac agacatccct attgccaata gtattttgct taatttcata
    75061 atgaaatcct cctataaatt ttataatatt acttaaatat tataattcta cataaaagaa
    75121 tattttcctt tatgaaatta gtttatattt caaaattttg tcacttttta aatctatata
    75181 ctaaaaaata gactatttgt aacagtctat ttcttagtat atcaaatatt tatttaggtt
    75241 tacgtttctt tgtactagtt tttgtatatg atattccagt tccaggtata ctcaatgtag
    75301 ctgattttct tccttttgaa ttaactgaca ctctagcacc tttaacacca gcacttatac
    75361 ctacactctt cttacctaaa tttaatttga gtcctcctcc tagatttatg cttttcctaa
    75421 agttaaatcc catagatata accttccctt ctatatttta aatatttata cttaaaatta
    75481 tatttgttat acacttgtca tcattggtat atctagcatc tatatctttt tacgtttttt
    75541 cttcttatat actactccag caactacagc tgctgttcca gctccaaccc cataagtagc
    75601 atttctactt ttctcttctt ctcttttttc taaaccttca tcatatacac cttttaactt
    75661 agtttcaata gacttcattt catctggtat actaaaatct tcttcattgt aaccttgatt
    75721 atatacactt tcttttgctt taggtaactt aaccttacca ttatcatatc cttctttaaa
    75781 ccaattagca tatttaacat tacctatagt tgatgtgtca aatctttctc ctttgatagc
    75841 actctcaaat ccttgagtag tgtaatcatt ttttaattgt tcttgtattt cgtcataagc
    75901 attattataa gcatctataa attcagaatc tatgttttct tcaaatgtca ttttttcttt
    75961 atctttattg ctatcctcta tccctttagc tttatattct tctatctttt tagtcttata
    76021 ttcattgtat ccagttgaat atccggtatc ataagcattt tttaaagctt ctttttcata
    76081 tgtattatta gatttagcac ctgtaagccc taaattatat ccagtctctt tagccacctt
    76141 ttcttcctct tctaatttag ccttaccttt ttcatatcct tctgagtact ttgattcata
    76201 tgtatcacta taatctccac tataatttga tgaactataa tttcctttat acccatcttc
    76261 atacccttga ttatatcctt tttctccaac agacctcttt tgcttttctt cattattaac
    76321 cgaagttgtt gttccagaac tgcttcctcc tccagtataa ggacaaccac cattattatg
    76381 taaatgagct ggataaccac cacaatgata gtgataactt cctaatccag atttattttt
    76441 attatcacga tgacctcctg atgaatcagt tcttcctgaa tgagcatacg aaaagctccc
    76501 tacactaatc atagttatac tcattgcaac agctattaac tttttcttaa acataatcta
    76561 tttcccccta aaatattcta tgattttatt atatcagtca atatattatg tttaaaccgt
    76621 taaaattcga caatgtaaat atttgatgaa ttgtatttgt aaataaatct tttagcatat
    76681 cttgaatatc tgtagttgtt ttgacatcat attcttcaat aagtttttta atatttcgtt
    76741 tttgttaaac ataaaaagcg tgcactttcc tttgtatagt gatatttgat attttaatta
    76801 tcactacttt agaagaatac acactttatt ttaaaaaccc tgatactatg ttattagaaa
    76861 atggtactaa tataaaagat atccagcata tactcggaca tgctaaaact tcaacaacta
    76921 tggatacata tttacatgta actaataaca tgagaaacca gacggtaaat atttttgaaa
    76981 tcattgtaga ataaatttgc cacccaaaaa taattatggt ggcaaatagg tggcaaatct
    77041 acttttaaga cacactataa aagtctgaaa ccctgttatt ctctaataag tttaactaca
    77101 gtctcacaat gtggcgtatt tgggaacata tccatacact taaccatctt aatctcataa
    77161 ccatacccct taaaatcaac caaatcaaca accaaagact taggattaca agaaatataa
    77221 acaatctcct tagcaccaaa tccacaaata tccctaatag catccttatg aatgcctggt
    77281 ctaggagggt caacaataat caaatcaggc ttgtccttta aatccttaac aaccttagcc
    77341 acatccccag caataaactc acaattagta agtccattca acttagcatt ctcattagca
    77401 gcaacaacag cttcctcaac tatctcaata ccatacactt tcttagcagc accagccata
    77461 acctgtccaa tagacccagt accactatac aagtcaaata caactttatc attgtaatct
    77521 ccaataaaat ccctagcaat actataaaga acctcagctc ccttagtatt ggtttggaaa
    77581 aacgaaaatg gtgaaatctt aaacttaaga cctaaaattt cttcttgtat ataatctctt
    77641 ccatacaata ctcttaactc atcacattgg actgcatctg ctaaaccatc attaatagta
    77701 tgaagtacac ctactaactc agcttttaaa tcaatcccta aaagcatatc tttaaactca
    77761 tacatatcaa aatcttcttg agaagaagtt actatattaa ccataatctc attagtatga
    77821 atcccttttc taactacaag atgtctcaaa tatcctttgt gattcattgt tctataataa
    77881 ggaagctttt tttcattgaa aaactctaca ctagaaacta atatctttga gaagtcttca
    77941 tcaaccaaca tacactcctc aacagtttgt atatctatat gctttccttt tttatgaaga
    78001 cctaatgtca aaggtccatt ttttacttca tctccaaaag tatattccat cttatttcta
    78061 taatatttgt tttctggact tccttctatc cctaaaaact gaaatccaaa taaatcttgc
    78121 tttaaaaata aatccataac ttgtttttct tttatttcta attgtttttc atatggcaca
    78181 gacaatagtg tacatcctcc acactctcta aagtgcttgc aagtttcttc agtttcaagt
    78241 ggtgagttct ctaataattc tatcatctta acttcagctt tcttacttct aactttttta
    78301 actccagctt tcaccttttg accacttatt ccacccttca tatggataac tctatctcca
    78361 acttggctta aagatgtgcc accaaattcc attttatcta cttcaaattc tataacatct
    78421 tttttcttca cagacattcc tccaatttac tatagtatct ttattatctt tcttcaatca
    78481 attttacttc ttcatctgtt aactctctat actcacctaa ctctaaactt tcatccaatt
    78541 ttaaattgcc catagacaat ctttttaagt atactacttt tttgcctacg ctttcaaaca
    78601 ttctttttac ttggtgaaac ttaccttcat gtattgtaag ctctatttct gattcatcat
    78661 cactttttaa tatatttaac tgtgatggca tagttttata tccatcatca agcactacac
    78721 cttctaaaaa agcttctaca tcttcttcag taactactcc atcaattttt gcataataag
    78781 tcttaggcac atgcttctta ggagataaaa ctctatgaga aagctttcca tcattagtta
    78841 aaactaataa tccctctgtg tctttatcta atcttccaac aggaaatggt tcaaaagcta
    78901 agtatgataa atcaattaaa tctaatactg ttgggtcata tttatctgta gttgctgata
    78961 tatatccatc aggtttattc atcatcaaat atatatattc tctatatata acttcttctc
    79021 cattaaataa tatctcatca ttttcagtgt ctacttgagt tcctgtattt gaaacttcac
    79081 ttccatttac tactacagac ccttgtttac aatacttctt tatttcactt ctacttccat
    79141 aacctaaatt tgaaagaatt ttatctatac gttgcttttt agccattaaa aatgctctcc
    79201 attctcataa tatttttctt tttcaaatac tgtaaatgct aaatccatac tttctacatc
    79261 taaattattt cttatactat cagttattat tcttgctact atatcttgta cttcttgtcc
    79321 tctatcaaac caagctactt caacaaaagg atatacatct gctattttac catctcttat
    79381 tgcaactgac tttatacatt ctatttcaaa gtagtctctt ggacatttta cagcttcaac
    79441 taaatcattt atcatttttt cacttatttt acatatatca ttttcattaa ttcctcttat
    79501 ttttatctgt ggcatagttt atctccttta ttttaaattt ttagtgaatt atcatccact
    79561 taattccctt cgataacgtt tgaagtggta acttcttggt caagacaact attgttatca
    79621 gtatctccaa actaataagg tagttcctac ccttatagtt agcattatat agctaatttt
    79681 cctaaattgt ttatattctt tattatttta tttaatccta ttgtcttcta tttaacatta
    79741 tacttgtaat ttatagttat tacaatttac tatatacttt ttttgattta acgttataat
    79801 ataagtgatg ggtaaatttt aaaagttaat aggaggagtt taaaatggca ttaattacta
    79861 caaaagaaat gtttaaaaaa gcttacgaag gtggatttgc tataggtgca tttaacataa
    79921 gtgacttaga acaattacaa ggtgttttaa aagctgctaa agctaaaaat tcttatgtta
    79981 tgatacaagc ttctatgtca gctgttaaat atgctggacc tcatacatta gttgaaatgg
    80041 ttaaggctgc ttctgatgaa ataggtgtag atgtagctct tcacttagac catggtccaa
    80101 atatggatgc tattaaaact tgtattgatg ctggtttctc ttcagttatg atagatggtt
    80161 ctcattttga ctttgaagaa aatgttagaa taactaaaga agctgttgaa tatgcacact
    80221 ctaaaggtgt tgttgttgaa gcagaacttg gtgttctagc tggaacagaa gatgatgtta
    80281 cttctgatgt tcacaagtat actcaaccag ctgaggcagt tgagttcgtt gaaagaacag
    80341 gtgttgattc attagcaata gctattggaa cttctcatgg tgctttcaaa ttcaaaggag
    80401 aagctaaatt aagattcgat atactagaag aaatccaaag caaattacca ggtttcccaa
    80461 tagttcttca tggtgcatct gctgttgacc aaaacgctgt tgctacatgt aatgaatttg
    80521 gtggaaatat agctggtgct aaaggtgtac ctgtagatat gttaagaaaa gcatcttcta
    80581 tggctgtttg taaaataaac atggatactg acttaagact agctatgact gctgctatca
    80641 gaaaattctt agctgaaaat ccaaaagaat ttgacccaag aaaatacatt ggtgctggta
    80701 gagatgctat acaagctgta gttgaaagca agatagatga tgttttaggt tctgctaact
    80761 ctataaacta atataacttt taaatattta taaaagaaaa gagatgactt aaagtaatta
    80821 aatttatttt taagccatct cttttaagtt gtatcaatta tgtatcttat aatattttaa
    80881 ttatattgtc tttttaaact gacagctaaa cgtgaatatg tccactcttt atctttctat
    80941 ggatggtaga aggatatata cctataactt cagcagcctt tgttattgaa ccatacttat
    81001 ttatagcctt acttatcatt atttggtcca ctattttata tgcatcatta agattcataa
    81061 ttccatttac cactattggt gataaatcat ctgtttcatt atcaatcata tctaaattta
    81121 tcagcatgtt aaattcatct tctccaatta catttttagc tgataatact acaaatcttt
    81181 caatgatgtt ttttaattct cttatgtttc ctggccaaga atattcttct aataactcaa
    81241 taactttagg cgaaacttct acttctctat tgtacttttc attgtaaagt tttaagaaat
    81301 aatttactaa tggtactata tcctcttttc tttctctaag aggaggtatt tttactggaa
    81361 taacacttaa tctatagtac aaatcttgtc taaatttaag gttatttcta aggtcttcat
    81421 gagaaatatt agtagcactt atatatctaa catctatttt tataggctta ctaccaccta
    81481 ttctagtaat agtattttct tgtataaccc taagtaattt tttttgcatc tgcattggta
    81541 actcacctat ctcatccaag aaaatagttc caccattcgc ctcttcaaaa agtccctttt
    81601 tacctttttt cttagctcca gtaaaagaac cttcttcata tccaaaaaac tctgactcta
    81661 ataattcatt tggtatagct ccacagttta tagctataaa aggtttgtct ctccttgaac
    81721 tatacttata tattgttctt gctattattt cttttcctac acctgattct ccatttataa
    81781 atatagaaga atctgaggct gcagctctct taacaacttt ttttatattg tccataatct
    81841 tactttgact tatatactct gtgtcttctg atatatcact atattttatc tgagattcaa
    81901 gcttaataac ccttgaaata tctctccctg ttagtactcc tcctgtaagc tttcccttag
    81961 aatcccatct tggaactgcc gtatatgcaa taagcttccc atctgggtaa acgatatttc
    82021 tataaatctt tttcttcact ttaagcatgt ttaatattat tggttcttca actaatcctt
    82081 gtctcacaag gtctgttata tttctaccaa gtacctcagt tcttttaaaa ggtaatatct
    82141 catcactgac agtgttcatc ttttcaatta ccccatcttt gttaaacaca acaacaactt
    82201 catctatatg ctctattata tcttcaatta ctttatcaga tattagagac ttctcaaata
    82261 aataaactat attattttca ttattattat ctttcatatt gtatatatgt gcagtcatcc
    82321 ttaactctct gaaagctatt ttctttttac tatctgtcag tatttctgtt ttgtcaaaat
    82381 ttgaatctaa ttcatttata tttctaggct tttttatatc tagaaaacta aaaatactat
    82441 ctattagatg attacagtat attatttcgc ctgattcttt acataaaatg gctggatttt
    82501 ctacatgttc tataagccct attaaattat tatccattaa tattcgcacc tttcattaag
    82561 taatttattg aactacatac aaaatttatt gtttgcttac aataaatacc atcagcacat
    82621 ataatcaact ccttataata ttcgtctttt caagtagttt atttcattaa aacgtaacta
    82681 agatataatt ttaatgatta tagtttgtta aaaatttcat tttgctttta attgtatttt
    82741 atcacatatt tagtaattat ttgtctattt aatacaattt aattaaattt aagatttatt
    82801 taaaaaaaca aagataatcc ttacagaata taactcacaa tttgtaagca atatacatat
    82861 aaggattatc cagattatct tgtattataa aattttattc aaacagactt tttaataact
    82921 gacaaataca cactagcaat aacttatcaa agggttaata attatgttac taactaataa
    82981 gacttattca atcagtaata tttatatagt ttgtatctat taagctttta tagcttctaa
    83041 taaatcatca acgctatcta atttttctat aagcattgga actatttcat gtaagtctcc
    83101 aactactcca tagtcagcga tttctaaaat tggagctgct gggtttttgt ttatagcaat
    83161 tatgaaatct gatgattgca tacctgctaa atgttgtatt gctcctgata taccacaagc
    83221 tatatatagg tttggtttaa cagtagttcc tgtttgacct acttggtgag aatggtctat
    83281 ccatccagca tcaacagccg cacgagaaga accaactact ccacctaatt tgtcagctaa
    83341 tttcttaagc atttcaaatc cttctggtcc acctaatcct agaccacctg atactataac
    83401 atttgcatct gtaagagata ctaaatcttt cttagtttta actgtttcta aaacagtagt
    83461 tcttatatca tcttgagtta ttttgtagtc taatgctata acttcaccag ttcttgtttc
    83521 gtctttttca gctttatcca taacaccagg tctaactgta gacatttgag gtctatggtt
    83581 tggacaaatg attgtagcca ttatgtttcc accaaatgct ggacgagttt gttttatttt
    83641 cttatcttct gggtctattt ctaacttagt acagtcagct gttaatccag ttccaactct
    83701 tgaagctatt ctaggtgcta agtctctacc tatatgagtt gctccgaaaa gcattatttc
    83761 tggttttatt tcatctattg catcttttat tacttttgta tatgcatcag ttgtatattt
    83821 ttctaaaaga gcatcatctg caacataaac tttgtcagct ccaaaagtga ttaattcttt
    83881 agctaatcca tcaacatctt ttcctaataa tattgcacaa agttctgcat ctacttcttt
    83941 agctaatttt cttccttctc ctaataattc tataactact ggagctattt ttccttctct
    84001 ttgttctgca aatatccata cgtttttata agaacttaaa tcttttatat cattcatagt
    84061 ttgtactcct ccaacttata taatgtgctt ttgttttaga ccgattatta ttttactagc
    84121 tatttcatca gctttacctt ctaagatttc tccttttcct cttggttcag gagtaaatga
    84181 tctaaatact ttagttggtg atgcttttaa accaacttct tctttattta catctaaatc
    84241 atcaattgtc caaactttta catcatgttt atatgctttt actattttat caacagacat
    84301 gtatctaggt gtatttaact cttttactgc tgttaaaagt acaggtgtac ttacttttat
    84361 taattcgtat ccatcttcta attgtctttg aactattata tcttttcctt ctattttgaa
    84421 atcttgtaca tatgtaactt gaggaatgtc taatttctct gcaatttgtg gtccaacttg
    84481 tgcagtatct ccatctattg cttgtcttcc tgcaaatatt atgtcatagt cacctacttt
    84541 agatattccc gctgcaatag tatttgatgt agcccaagta tcagctcctc caaatgctct
    84601 atcacttaat aatattgcat catcagcacc catagctaaa cactctctta gcataaagtc
    84661 tgcttgagga ggtcccattg ttataactgt tatagttaca tcatcatgct catctttaat
    84721 ttttaaagct tcctctaatg catttgcatc atctgggttt aatatacttg gaactccatc
    84781 tcttataaga gtacctgttt ctttatttat tcttacttcg ttagtatctg gaacttgttt
    84841 tacgcaaact aatattttca aagtctatac ctccaatttc attagattat ttattatttt
    84901 aatacgtttg atgaaattac cattttttga acttctgatg ttccttcgta tattgatacg
    84961 attctagcat ctctgtacat tctttcgatt tcataatctt ttataaatcc atatccaccg
    85021 tgaagttgta atgctttata agcaacttca tttgcaattt ctgatgcata gtatttagcc
    85081 atagcagatt cttgagcaac tctcattcct gcatctctct tttgtgctgc atcataaact
    85141 aatcctctag ctgcacaaac ttttgtttcc atgtcagcta tagtaaattg agtattttgg
    85201 aatttagcta taggcttacc aaattgaact ctttgttttg tatatttaac agcttcatct
    85261 aaagcacctt gagctattcc tagagctaag gcagcaacac ctattctacc aacttctaga
    85321 gtacccattg ctatcttaaa tccttgacct tcttttccaa gtaagttttc ttttggaact
    85381 ttaacgtttt caaatattaa gtcagaagtt tcagttcctc ttatacccat cttatcttca
    85441 tgagctcctg ttgagaaacc atcccattta ctttctacta taaacgctga tgttcctcta
    85501 agtcctttac ttctatctgt aactgctatt actatagcta catcacagaa tggtccatta
    85561 gttatgaaag tttttctacc atttaatata tagtggtctc caactaattc tgctgttgtt
    85621 tgttgtccac ctgcatcaga accagctcct ggctcagtta aaccaaatgc tcctattaat
    85681 tcacctgttg ctataccttt taagtatttt tgtttttgct cttcagtacc attgtaaagt
    85741 attggtaatg aagcaagaga agaaccagct gtaacaaaag tagctgttga agcacatctt
    85801 ctagctattt cttccattac tatagcgtaa gaaacatatc ctgctccccc accaccatat
    85861 tcttctggga tattactgct tataaatttt gcatcagcta attttttgat taattcctta
    85921 ggcattacac ctgttttatc catttctgct ggtaaagtat ctaattcttt actaacaaaa
    85981 tctcttactg cttttcttaa aagttcttgt tctttgttat ataacatagc ttcctccaat
    86041 tttcatattt tatagtaaat ttattttaat gaacttacgc taaactcatc atctcagcaa
    86101 aagtttgaat acgagttctg gcttgttcat tattctgagt ttgttggtcg atttcaacat
    86161 ataaagtagg tattccacta tcttctatat cttttctaac taaaggataa tcgtattctt
    86221 ctgggtcaca gaatttcatc atacagaaga taacaccatc tatatctttc tttttaactt
    86281 catctactat aagtgaccca cgttttttct tagggtcata agctaatgaa catccttcta
    86341 tgtttgacca ttgtcttgct aatctctcta acgcatcatc acctgctggt acatctgttc
    86401 tgaattgtct tgtttcttgt gctaagtcgt cagctacaac tgatatattg ttgtcttcta
    86461 aaatgtctaa tatatcttta gaatcagcta atatacctgt taataaaact ttctttccag
    86521 aacagacttc ttctggcata gcatttaatt ttgctattaa atctttcact agctcagtat
    86581 gttcttcttt tctcataaag aacccactct taattactaa gcttcttatt gatggtttta
    86641 tagtattaga atgtttataa gctacttcaa caaagtctct catagttttt ctatgttcat
    86701 tgtaaacttc tatactttca tgaatttttg cttcttctat ttcatatcca caaatttctt
    86761 caagttctct ttttacgcct ttgtactcac tgattaagta ttttacacca gcttcaagtt
    86821 ttctattttg tgggtgtact aatgatatat attttatatg aggtactgct gatttccagt
    86881 tttgtcctaa acaaattagt gtatcacaca tacctggtat aataactcca gataattcat
    86941 cataagcacc ttttaatcca tattctaaac atgattgcat tattgaacat gcaaatgcag
    87001 ggaaatattg tttagctaaa tctaattctg tttgtcctcc ccatatacca actggaagca
    87061 ttccagctgc atgtataatt tcttctgggc aataaactgg gaaacaacct atagcttttt
    87121 taccagtttc acttttatat ttttttacag ccgcatttgg attttcaact acttctttca
    87181 ttttagataa aatagcttcc attatatctc acctctatta agtttttttc tttcttccat
    87241 tacttcaact aaaccttgaa ttcttgtttc aaattgagca ttagtgaaag ctctagggtc
    87301 tgcttggtca ccatcaaatc cagcatatgg taatccagtt tcttcagctg ctcttctttg
    87361 catttcatat tgtattaaac tcataagttt acagcttctg ttcatatgat agaatgctcc
    87421 atcacattta ccctctacta aagaatcaac tctatatttt gtcatacgat ctaggtttac
    87481 attgttaaac atagtactat atgctactgc cattccatct aaatcattaa cttcatattg
    87541 taatgcccaa gcatgtgggt aaacactacc tgtcatgtta actccaaatt tagctaatgt
    87601 tttcatcttg tatcctatat atggccaaca aggtatacct tccatcatta ttctgtattt
    87661 ttcttcccct ctgaaagaag atttaccagt tttcatgttg tcctctaatt cttctataag
    87721 taacttaaat gcttctgtag tttctttttt acctctagca caaactatta cagccatgta
    87781 agtaaataag tcaaatccat tcattggaga aggagaagaa tctgctggta aactcataga
    87841 atacttccat agtcttccgt tttcagctga tattttcatt acttcttcaa acttcttagg
    87901 gtcaaatttc tttcctgata taatttctag ttgttttata gcttcttcaa attgagcttt
    87961 aatataatct attcttgatt gagtaacttc gtcttcatta ttgaaagttg tatcaatcat
    88021 tattaaaggt atatctaatt ctcttgaaat attttcatac cattttataa cttggttaca
    88081 tatattgtta cagcaaagta ggaaatctgg agctggcata tccaaagctt cacatccacc
    88141 attttctaaa agaccaaaat ttgttcttgc atatgcacat aggtcaatag aatatccttt
    88201 agattcagct atttcacata attctaaaga acctttttta gctgctactc cagctgcttg
    88261 gttttctgga tataatacgt ttaagtcaaa tacttctgct aactcttgag gaaatactga
    88321 tgttgaccaa cctacaggtc ttccttcttc tttagcttta aatgcatttg catattgttc
    88381 agctaataaa tcattaatta ctactctagc ttcttttttt tcagacattt tcatccctct
    88441 ttttatatat ttttcacttc tttttgtgat tcttttgctt catcaaaagc atataacgct
    88501 gctcctaaag caccagttaa ttgaggtata tcaggtacaa taatttctgt gttgatttct
    88561 cttgccatag ctcttacaat accactattt ctagcaactc caccaaccat aactacattt
    88621 ctttgtactc ctattctttt tactaggcta gaaactctct ttgctactga agtatgaata
    88681 cctgccacta tatcttcaat ttttgcattt tcagataaat gtgatataac ctcagactct
    88741 gcaaatactg tacatgtact gcttattgat acttcatttt gagaattcat agatatactt
    88801 ccgagttcag atacatcaac ctctattatt tttgccatta catctaaaaa tcttcctgta
    88861 cctgcagcac atttgtcatt cataagaaag tttaatagtc ttccattatt atctaatttt
    88921 aatacctttg catcttgacc acctatgtca ataatggttc ttgtctctgg aattatgaaa
    88981 tttacccctc tagcatgaca gcttaattca cttatttgct tatcagcatc tgaatagttc
    89041 attcttccat atcctgtaac tacaactttt ttaatatctt ctcttgcaag acctgtcttg
    89101 ccatataatt tttctaaaac tcttgatggt ccagtagtcc cagtaccaga ggatattgtt
    89161 tcagaagcta caatatcttc cccattcttt aagattactc cctttgatgc agttgaacct
    89221 atatctaatc ccattgtgta catctttagc attctccttt taaaaaatct agaattacta
    89281 attaatatct tacaacttta ctatctttaa agttatttat tttctcttca tcgtagccta
    89341 aagattttaa tacttctaca gtatgttgac ctacttttgg tgctggtgta tattctttaa
    89401 ttccttcatt tctaaacata actggagtat taactaagac acctgtattt ccgctatcgt
    89461 atgttttctt aaataagaag tcatttgccc aagcttgttc gtcatctaat aaatcttcac
    89521 agctttgaat tttttcaaat ggtaagtctg cttcttctaa taaagctgac cactcgtcta
    89581 atgttttttc taacatagct tctccaacta tcttaactaa atcttcaaca tgattaacca
    89641 ttgaatctat gttattatat ctatcatctt ctaatatata ttctctattt ataaccttac
    89701 agaatttgcc taaccacttg ttgtattgta ttaaagctaa ttgaatccat cttccatctt
    89761 tacatttata tgtagtcatt aatgggctgt ttggattttc tcttgataaa ggcatttcat
    89821 ttccgtattg tgctgttgtt atcattgttc ccattccata tatagctgta tggaaaagac
    89881 ttactgttac tctctcacct ttaccagttt gagctttttt atgtaatgct gctaaacttc
    89941 ctgctgctag tgctagacct gcatagtggt caccaaatcc tgctgctgta tttgctggag
    90001 atgttccttt ttccataaca gattggctaa ctcctcctct tgcgaagtat gcagtatagt
    90061 caaatcctgg tttatctttt aaaggtcctt tttcaccata tcctaatatt tgagagaata
    90121 ttaatcctgg atacttatct tttatttggt cataagctat acccattttt tctaatgctt
    90181 gaactctaac attagttaca aatatgtctg cttctgataa taatttatgt aatatttcta
    90241 ctccttcttt tgattttaca ttaatactta cacccttttt atttccattt tctaattcaa
    90301 acatagggtt ttcatcatct gatgctggag atttaaatgt tccacccata actcttattc
    90361 catcaccttc tataggttca atcttaataa cctctgcacc ccagtcacct aacatttttg
    90421 cacaacatgg tgctgcgatg aaacttgaaa gttctactac tttaactcct tctaaaagca
    90481 taacgttttc ctccttaata gtatcaatta taaaatttcg attaaatcac tcataaaata
    90541 cttttttctg atattaactg tctgatgtca aagttcctaa tcttatctaa aataacttaa
    90601 aaattattaa aattattttt tattgtttta ttgtcttaca cctatattgt taagcattta
    90661 tcgtgccaac tttatattta atcaaaatat cgcttgattt gaatgttttt taacaatatg
    90721 caattgaata atctttttca tatcgtggca tcttgccact atccattgca ttttgctatt
    90781 ctttctatgc ttataaaagt tttttttata tattttttta tgaaaaagct tgacatttca
    90841 aaaaaagttt tcattgctaa actcaaaaac acatgttatc attgtaatta atcagcaagt
    90901 tagttaacta atttcaaact tagataattt tttaataata tttaatctaa aaaataacaa
    90961 tttctttgat aaattttaga gtaattatta cattaaataa aaaattacta aatatcaaaa
    91021 taacacaggg aaaacaattt caaaactaaa tttttaacct taaaaatttt gtataaaaaa
    91081 tataacctta tatgctacat attatttcta aatgaaaaat taccataata atttaataat
    91141 tacaggaggg tattgatatg aaaatactag tatttggagc acgcgattat gaagaaccag
    91201 taataaaaaa atggtctgaa gaacataagg atgttcaagt ggatatttat cctgaaaaca
    91261 tgactgaaga aaatgtagtt aaagctaaag ggtatgatgg tatatctata caacaaacta
    91321 actatataga taatccttat atttatgaaa ctttaaaaga tgctggggtt aaagttatag
    91381 cttcaagaac tgcaggggtt gacatgatac attttgattt agttaatgaa aatggactta
    91441 tcgttacaaa cgttccttct tattcaccta atgcaatagc tgaattagct gttactcaag
    91501 ctatgaacct tttaagaaag actcctctag taaagaaaaa agtctgtgaa ggtgattacc
    91561 gttggatagc tgaacttctt ggaacagaag ttagatctat tacagttggt gttataggta
    91621 caggaaaaat aggtgctact tctgcaaaat tattcaaagg cctaggagct aatgtaattg
    91681 catttgacca atatccaaat agtgatttaa atgatatatt aacttacaaa gattctttag
    91741 aagaccttct aaaagaagct gaccttataa cattacatac tcctttactt gaaggaacaa
    91801 aacatatgat aaataaagat actctagcta taatgaagga tggagcttac atagtaaata
    91861 ctggccgtgg tggtttaatt aatacagggg atttaataga agcactagag tcaggaaaaa
    91921 ttagagctgc tgcccttgat acatttgaaa ctgaaggatt gttcttaaac aaaaaaatga
    91981 atcctggaga attaactgac ccagaaataa ataaacttct ttctatggaa caagttatat
    92041 tcactcatca ccttggtttc ttcactagta cagcgattga aaatatagtt tattctagtt
    92101 taagcagtgc tgtagaagtt ataaaaacag gaactgctac taatagagta aattagtatt
    92161 ttataaatat attttttcat taattagcta ttatctaaca aaatagcctt taatttccca
    92221 aatataagag agtcagctca gtatatattg agtagactct cttatattat tttttatatt
    92281 aaacttgtac tcttcttatt cataccaaat taaatttata ttaacttatt ctaactactc
    92341 ctactctata cattttacct atttttactt ttctaattat atacatttga atgggtacaa
    92401 tctgtatttt acaaaaaaaa cacctaacaa actatgaaaa ttgtatgatt aatattaata
    92461 tatttataag aaaacataac aattatgtta gctctggatt tttagggagg gagtatattg
    92521 gaaaaaatga ataaagttac ttctaaaaaa actacctata ttgttacttc agcattattt
    92581 gcatccataa tatgcctgac aatagcatat atattacata ttccagttgg tggaaacaat
    92641 ggatatgttc atataggaga tgcttttatt tatctagctg caactatttt gccaacaaac
    92701 tatgctatag ctgcttctgc aattggtgct ggtctagctg atttatctac aggtgctgct
    92761 atctgggtaa taccaactat aatcataaaa ccaatacttg tattattttt cacttctaaa
    92821 agtgacaaga taataaataa gagaaatata gttgcttcgg ttgtagcagg tatagtagga
    92881 ttagttttat acatgtttgc tgaaggtata attattggaa gttttacaag tgcatttgta
    92941 atgagcttac ttggcttatt acagccaata ggaagtttta ttgtttttat aatcttaggt
    93001 atggcacttg ataaacttga ttttaaaaaa cgttatttta attaagaatt taaatttatg
    93061 gagggaaaat tatgaatatc ttatatacaa ttgaaaatag tatctatgta aatataacta
    93121 atacatgtcc atgtagttgt gttttttgta taagaaacga aaaagatgaa gttgcaaata
    93181 gtggtagttt atggctggaa catgagccaa gtgtagatga agtaaaagaa gccttcaata
    93241 aatacaattt agacgactat gatgaaatcg tattttgtgg atatggcgaa ccattaatga
    93301 gaataaatga attgatagag gtagcaaagt ttataaaaga aaaaagtagc ataaagataa
    93361 gaataaatac aaatggtcta agtgatttaa tacataacaa aaaaacagct attctgttaa
    93421 aaaatgttat agatgcagta tcaataagtc ttaatgcccc aaataaagaa gcttataata
    93481 gagttactca accaaagttt ggagaaaaat catttgatta tatgttagat tttgcaaaag
    93541 attgcaaaaa atatataaaa gaagtagctt tttcagtagt agatgaaata tctccagaag
    93601 aaatagaaga atctaaacaa ctggcaaaaa aacttgatat accattaagg gttagacata
    93661 agaattagca agtaaaatta taaaacatta attataaaac attaagaatc acctgaatgg
    93721 tctttcaggt gattcttcct cttgtattaa cattttacaa aatagatttc ataccacact
    93781 aggaatgtgt aaatcatcca aatctttctc caattatcag agtttccact aatgtagtca
    93841 ttaaaaatct cattaatctc atctatgtta aagaatttat ctgctatctc actattgaat
    93901 ttatctcgga tgtccttatt atattggtca tcagccatcc atatacgaat tggcacaata
    93961 aatcctaatt tatttctaaa agcaatctct tctggtaatg tttttgatgc agctgtacga
    94021 aaggcaatct tattctcttt tcctttcact ttatattctg atggtattct ggatgcaata
    94081 tcaaatattc ttgtatctgt aagaggcatt ctgacttcca atccaactgc agtactcatt
    94141 ttatctatat taaaataaat atctccttcc aaccatattt gaatatctac atttgacatg
    94201 ttagtaagtg tatctagttc ttctgtttct tcataaattc cctttaccac ttcaatagga
    94261 agcacatcag gattgtattt cttaagaatt tttcttttct caccctcatt cataatgttt
    94321 gtatttccaa tataaaatgt cttcaaattc tctccataac actctgcctt atggtatata
    94381 ttatatccac caaaaaactc atctgctcct tctccagagt aacagatatt tgtgttttca
    94441 gctgctgcct tgcatccaat agcaaaaacg atagcagatg catctccagt tggttgctcc
    94501 atatggtaca ttacataagg tactgacgca aaatactctt caggtgtaat tatatatctc
    94561 gaatttttac acccaagaat attagctgtc tgttgtgcta attttgattc atcaaaacgc
    94621 tcttcctcat aaccacatga acctgttttt tctatatctg acattgccaa tatataagat
    94681 gaatcaacac ctcctgatag gaataactct gcagtttcat tctctgattt tacctctggc
    94741 ataattttct gaagtgttgt atgaatttca tccgtccatt cctcaataga cttgctgtgg
    94801 tcaggatgaa attcaggttt ccaataacga ccaatacata ctgttttatt ctgatagaca
    94861 aggtaatgtc ctggcataag cttctttact ccacggaaga atgtattttc acctgctaca
    94921 tatgtgaaag acatataaat ctgtaacatg tcttcattta actctttcac aaatcctggt
    94981 tgctccataa tcttacgaat agatgaacca tagagaagct tcccattttc agtctcataa
    95041 taatagaaag gttttactcc aaactggtct cttaggcaga agagtttctt ttccacagta
    95101 tcccataatg caaaagcaaa cattccatgc atgtgatttg ccatatcata tccccatgtc
    95161 ttatatgctt ccactaaaat tgctcgttca cgctcatctc tacataatga agaatcgatt
    95221 ccaagttctt cacagagaac tttccagttt cgaatatgtc cattgtattc tagaattttt
    95281 atcatatatg tgtcttttcg tgttaaatac ttttcttcta aatttatcat atgtgtatcc
    95341 tttcgtatta aaacatttaa cttctaaatt tattaaatgt ttatatatat ttattcactt
    95401 ataatcactg aaaaatcgac ttttttcaaa gtaaattctt tttgaattag tactaatctg
    95461 ctctttatta atggcatcaa tatgattatc aagtattatc agtgttataa cactgaattt
    95521 tttattcttc ataaatattg ctccctttat attaccaact aaatataata tatcttatgt
    95581 tacttacata ttctttaaga aattctgaag attttataaa gttttttgta ttataatcaa
    95641 ttaaaaataa aattctagtt ataaagcata ttttccatta aacaaaaaaa tagttaaaat
    95701 aaattcataa ctacataaac ttattttaac tatttgtata ttttaattat aaatattaac
    95761 ttaaattttt aacaggatac actcataaaa taaacataat gaacaacaaa ataatatgtc
    95821 tcagtttctt tatacacttt accttctttc aattttctac catgtagacg tacaagataa
    95881 tattagtaat tcactctatt gctgtaattt actctattgc tgtaattcac tctattgctt
    95941 aactcgtgcg atatggacaa ccaagaaagc tatttcctca tttgttaact tttttccata
    96001 tttcttttct aaaaaatctc taacttttaa tgcaattaac atttcttttg gatttgacct
    96061 tttcatttga ttaaataata aatcatcacc actgcttaac atactatctg aaaaaaatct
    96121 ttccacaaaa aattttatat gtgttataaa tctcatataa tgcatactct ttttatctaa
    96181 ggttctattc aaagaaaaaa caaaaatatt aattatttct ccaattactt tggcatactt
    96241 aatcgtatca tatgaatttc catctgaagc catagcattt gcaaaatgga aagcaatgtt
    96301 agctgcttct tcctctggta attgaatgcc caatctctcc tctaccatat aaattgcaac
    96361 cattccaacc ttaaactcat ttggataata attttttatt tcccaaaata ctcgatttgt
    96421 aatttttatt cctttacgca tcctttcaat tgcaaagtta aaatggtctg ctaatattaa
    96481 gtataagttt ttattaaaag atgagttcaa taacttttct gcctctacta ttatttcctg
    96541 tgttatcttt aaaatgtcga caggaatatc atccattaat tctaaaaatt gttttgattt
    96601 tgtattttca acagggacaa acatttgatt atcattggaa ccacaaatat attctcctgt
    96661 ttttttacca tatccaattc ctttccctag caaaataaat tcattatcct ttgtgtcatg
    96721 aactaaaaca acgctcgagt tcaaaacttt ctttattatg tagttcattt tatttgctca
    96781 ccttctattg gtcatttaaa atctatacta ttattttcaa ttactttttt ataccaataa
    96841 aaactatctt tcttatatcg attatatgtc ccctttccat aatcatcagc atccacataa
    96901 atatatccat aacgttttga catttgtttc gttgattcac tgaccaaatc aatacaaccc
    96961 catgaagtgt atccccaaag ttcaacacca tcttcaataa tcgcatctaa catacattta
    97021 aagtgttctt ttaaataatt aattctatat tggtcatgaa cttttttatc ttcagttaaa
    97081 atatctttag ctcccaatcc attttcaact ataaataaag gctttctgta tctatcatat
    97141 aattcaatca aagatatacg tagacctatt gaatcaattt gccaacccca ttcactcatt
    97201 tctaaataag gattttttac agctaataac gtattcccag gtgtaatatc taatccagtt
    97261 gtatcagctg cctcacaaga agacatatag taagagaatg aaataaaatc tactggatac
    97321 tttttcataa tttcatcatc atgttcttct tttactattt gaatgttatt atttttaaaa
    97381 tacgacagta aatatactgg atactcacca aaaacctgcg tatcactata tgcataaata
    97441 cttctcattt tttgttgagt tgccaaaaca tcttctggtc tacatgtgta tggataatac
    97501 gttaattttg ttaacataca ccctactttt gaatttggaa taatttcatg acaaattttt
    97561 gttgcaaggg cactagctac aaattgatga tgcatagctt gaaaaataac ttcctcaaag
    97621 tttttatcct taaaacggtc tcgaactaaa ccaccagtag tgtacggatg acgaatcata
    97681 gaatcaactt cattaaatgt aagccaatat ttcactttgt ttttatatct ttcacagata
    97741 gtttctacat acctaacaaa catattgata acttgtcgtg aataccatcc atcatagttt
    97801 aaaacgatat ttaatggtgg ttcataatgt gacatagtaa caagtggttc aattccataa
    97861 cttatcaact catcaaatac atcatcataa aactgtaaac cttcttcatt tggctcttta
    97921 tcatctccat ttggaaaaat acgagaccaa gcaatactca ttcgatatgt cttaaatccc
    97981 atttctgcca ttagagcaat atcttcttta tagtgatgat aaaaatcact accatgacgt
    98041 tttggataat ttacttcatc ttcaggatgt gctaatcctt cttctatatc ttttgttgtg
    98101 atttcattat tagatttata atctttcaca tctgcatcaa agtgtgcctt tgctacatct
    98161 gatacagacc accctttccc acctaaattc caaccacctt caaattgatt agcagctgta
    98221 gctcctcccc aaagaaatcc ttctggaaac tttctcatat ttatattcct ccctttacat
    98281 caaacaagat acttcctttt tttacattgc cataagactg gtttaacact ttataagcat
    98341 aatctgctcc attattgttt acaatcataa cagttgaatc taaattagca tgtgagattt
    98401 tgtctaaatc aaattgaatt aataaatctc cttcttttac attatcgcct gtcttaacaa
    98461 atgttttaaa tccatctcca ttcatactta cagtatttat tccaatatga atcaaaatct
    98521 cagccccatt ttttgttctt aaaccaattg catgttttgt ttcaaataac atcacaactt
    98581 ctgaatcaca aggtgcgtat aaatttccat tggttggtat aattgcaact ccatctccca
    98641 aagtcttact tgcaaatagt tcatcattaa ccttacttaa atctattact tttccttcta
    98701 ctggagttac taagatattt acttcttttt cttcttctag ctcttcttca acaacatctc
    98761 caattgatga ctctactgta tttgtatctt ccttccaaat aatcagtgta ataataaacg
    98821 agcctaatat tgcaataaca aaaccaatac ttgcaaaaat caaattgttt ccattgtttg
    98881 ggtcaataaa catactcata ctggcaagcc ctggtccaac aattacaaat ccttttactg
    98941 caaataatcc taaaaatgta ccagaaattg cacttgagaa tacaacacct aacattgctc
    99001 ttttatgttg taaagtaata ccatataaag ctggctctgt aattcccatc aaggcagaaa
    99061 ttcctgcaga taatgctgtt tgttttaatg tttcatcttt tgttcgcaag gctactgcaa
    99121 aacaagcacc actttcagaa atattgtggg ctaatgaaga tgtcatatat aaagcttcat
    99181 aacccaactt tccaattgta ttaattgaat aaggtattag tgctttgtgc attcctgttg
    99241 caaccataaa tggaagaaaa gcagcaagta atcctacaac taagaatccc attttgttat
    99301 ataagaataa aataatggtt gtaaaaattg taccaacgtt atatcctaaa ggacctaaaa
    99361 tagttagagt aattggaaca gtaattgcca aagacatcat aggaacaaag aaagttcgaa
    99421 ttggttttgg tgaatacttg ttaaaaattt tctccattgt tgccaagaaa gacacacata
    99481 agatagctgg gaaaacctgt gcattatagg caatgtttgg aattgtaaat ccaaatagtt
    99541 cgacaccttc acttaaagca gttgttgttg ctggaagcaa taagtatcct acagcggcaa
    99601 tagctactaa acgattacat ttcaatacat tggcagtagt tacagctacc ataataggta
    99661 ggaaatagaa tgttgcatct gaaatagcaa ctaataatgt atatatagta gaatctgatt
    99721 ttaaaatatt aaacattgct aataacatca acagtgattt taaaatacca gctcctgcaa
    99781 tagcaaaaat cagtggttga aaaatattaa taataaattc tataaatctt tttcctaagt
    99841 ttattttttc ttcagttttt acagtactat catttgtatc taaagggcaa acttttaaaa
    99901 tttcatcata cacatcaaca acactattcc caatgacaac ttgaaattgt gccccattaa
    99961 ctatactcat aacaccttgt acttttttta aagcatcctg attgacttta cttctatcaa
   100021 tcaacttaaa gcgtagtcta gttgaacagt gttctaaagc taaaatattt tttgaaccac
   100081 caacttgttc aataatgtca atggcagttt ttttataatt catcttgtaa tctccttctc
   100141 cataattttt tatgaatggc cattcaagat gcaaaaaagg cagaacctat ataaacacct
   100201 tgaaaaatca aagcaatata ttcgatcctg cctgcattac cagtaacatg tcttctattt
   100261 atactatttt gtattattat attaacattt gcctaaaaga attgtcaata cttttttaaa
   100321 ttttctgata ctaactaata gcacctttat aattcatttt ttatgtcaat taaagtaaca
   100381 gtagccaccc accaattagt atcaaaattg aacctggtat tttttctttt atattttctt
   100441 tgaatataaa atgagcaagt attaaagtta ttatcataga tacttgagaa aatggctctg
   100501 ctatactaag ttctagatta tttaaagcaa ttaataatgc taaataagaa tatccattaa
   100561 tagcaccact taaaattgaa agcccctttt tattagtaaa aatctcacaa attatttttt
   100621 gtttcttttt aaatgctaaa aagataaata aatttaaacc tacgaaaaaa tacagtatag
   100681 ttgaatataa tataggagat acttgtacaa aaaaagcctt atccaatact cttcctactg
   100741 actgcaaaaa tatgtataaa aacattaatc tacatggtaa attgttaaaa attacagaaa
   100801 cattctttaa aaaagagctt acttttttta atataaacac tccaccaatc ataattatga
   100861 ttcctgcaac ttttgctaaa cttaaacctt cacctaaaaa tataactgat aaaagcagta
   100921 aaaacaatga atttaaacta tttattggag taacaagtga aacttcccca gttgctaaag
   100981 acgttacata cgctactgaa ccaattgaat agactaaact acttatataa catggtatta
   101041 aaaacgacca atcactaact ctatccatta tgctaaatgg aagtaaacat actcccccta
   101101 taaagaaaaa tagaaatgat gaagctatat ttttataaat atctccttct tcatcaccta
   101161 ataatcttac aactactctt tcaaaagcta atagcactac tctaattaat aatgcaaaat
   101221 aagataatat catttttgac ctcgcttaaa aattaatccg acttattgtt atattaactg
   101281 tataagacta ccatataggt aagtcttttg gattttttaa tattttatgt ttaaatacag
   101341 gtacattaag tttttcacct agtttacggc attgctcttt ataggtacct tttaatttat
   101401 catgaaaaac tatacaatca attcctcctt caatactatt tatacacttt tctagtttct
   101461 caaatccaga ttcatcatca tacattccac ttacaatcca ttgatttggc aatacatgtc
   101521 caattgatat gttatattct ttatttttta taatatctga gaaagatttc tcaaaatgta
   101581 cccctccaac acataacaaa gtcttcaaag gttcatcaca atcaaatact ctaattaatg
   101641 attttgccaa tacctgtatt gctatactat tattaaaact atcactacta cttcctatct
   101701 caatatccaa cataggtaca gaatattctg taattaattt agattcttca ccatatgttg
   101761 ttccagacca gtgagttgct tctgttaatg tagtaaattc atcaagtaga ttttcatttt
   101821 ttatatcctc aatagcattg attagatttt taaagtatct tggatttgaa tttccaaatt
   101881 ctcctgttgg aacatctcca attgtatgag ctgttaggat atgttctgga gcattttctc
   101941 cctcatgcca atttacaact cctgcaaaat cataatctct aaaatgtcta tttaaaattg
   102001 gaagataata tttataatta tgacttatta catcttttgt ttttacaaaa tgaaataagt
   102061 tattgttttt atccttaaac tctaatacaa aattatcatc aataacaata tcagtttgat
   102121 ttaaatccat tatttcttca caacatttta tcacattact ggctactggg tctttcttta
   102181 aatcactgca aaagaaaaaa actgcttttt tattattcat ccataaatca cactcctata
   102241 acttaaatat aatatatctt catacctaaa atcatctaaa tatcactcta attccattaa
   102301 attatttata tataatatac taccatactc attttagcta tacctttgcc tgagtttcta
   102361 tatatatgtg atacatcagc tttaaatctt atagaatttc cactagatac aatgtaatct
   102421 tctccattta ttttaatggt tacttcgcca ctaaaaacag ttataaactc ttgtgttcct
   102481 ggaagttcag catttgaatc taaatttcca ccttcttcta tttcaatcat aaatatctca
   102541 aatcttcttt tggagtcaaa tggaaatatt ggataactta tatactttcc attatcttca
   102601 ataaaatggt ctatatcact tttttgaatc aattctatgt cactttcctg cctctccatc
   102661 aatgatgtaa atgagatttt tagcccatta gttattttct tcaaagtaga tatagtagga
   102721 tttacctcac acttttcaat ttgagatagc atactcttac ttacaccact aagttgtgca
   102781 atcttgtcta aactaagatg tttttctttc cttatctttt ttaaattttc agcaattatt
   102841 tcatttaaac tttgcataaa taccccctaa tacatactaa tataagataa attattttga
   102901 ttattaaata aacttagtaa tttaatagaa actttttatc cattataatg tacattatgt
   102961 ttaatataca ttactttttt tagaatgtaa atagttttct gaaattttgt gaaaatgaat
   103021 aaataaaaaa ctagtaacct atatttttac aaggttacta gcttttatta taataatctt
   103081 tcattttaac tataaaactt agatgcacct ataagctgtc tcttagaaac aatcttagct
   103141 aggtttgcta atgaagaaat ttttatatct ttaaaagaaa ctaaaaatac aaacttaaaa
   103201 tctgtaaatt cttgatttat attgtatata tcaaaataac atctcaaatt atcaaataag
   103261 taattatcct gtaagtctgc ttctatctca tcagtagcat cttttaaata cgctcttaca
   103321 tcttcaaata aaacactgaa ataagactca tctatttctt cacctaactc ttccaatatt
   103381 tcttctatat ctaaatcatc catatcaaaa gaatttcctg tcaactggca atcaaatacc
   103441 aatatatttt cttgatttat agtatttgat atatcttgta catattcgaa gtctggacgt
   103501 aattctaaaa tgtcttttat ttcactgctc tttacatgga tttttccttt tctattttca
   103561 atttttaaat ctatcatatg ctcccccttt caatctacaa atctttaaat accttgtttt
   103621 ataatctttt caatatctat ccaattacta actctaacta tattttgatg tttaacatct
   103681 ttattatagt tagtatccag aagtattact ttaacaccat catcagctag ttgcactgag
   103741 tttaaaggat tatcttctat aaatatgtca caactcagtt ctcttgcctt ttcaacttta
   103801 taatcacttc ctaataagta aacatctata tctgaaaatc cttgtctcga tagccaattt
   103861 ttagttacat cagttaaaca ctcatgtcta gccgttacaa aagataaatt atgtccttta
   103921 gataatgtgc taattacctc tgtagcaccc tctacaatct ttgcttcatc atatgagtgt
   103981 atatacttat tattaaactc cgcatacaca tctcttattc ccgaaccata caattcttcc
   104041 caattatgtg ttatacactc tgcttcagtt atatttttat taaagatatc atttaggtat
   104101 ggaagaaaat gataagggct tgttattgtt ccatctatat caatacatat attcaatttg
   104161 ttcattttta cctccatgta acatttattg atttgattaa tcaaatatta tagcacagct
   104221 ttaattataa atcaaaactc tggatatgac tatacctata taataccaaa aagcttgcat
   104281 atttaagcaa gcttttcgta aattttacat ttttaactaa tatataagtt tttctaaggt
   104341 tggttccact ccaaattgtg atttcagttc tttatattct tttaatgctt tgtcattatt
   104401 cgttttagtt tttatcgctc ttatcattaa attttttggt gtatcaagtg gagatatgta
   104461 ttctactaca gaagtatcat atccattgcc ctccaataac aatgttctta aaccatcagt
   104521 tattaaatct gcaaatctag ctttaaatac accatgtttt aatattggtt ccatagcttc
   104581 atatctatat tgccctaata actccttatg acaacatggt actactacta tagcttcaga
   104641 ttttgctcta attcctagac ctattgccat atctgtagct gtatcacaag catgtagact
   104701 tattacaagg tcaacatccc tattaggtgt ataattagtc aaatcctctt ttataaatga
   104761 catattttta taacccaagt ttttagccat attttttgat gcttctataa ctacatctga
   104821 ataatctatt cctataaaat aacagttttt cttcaatact tcttttatat aaaaatttaa
   104881 gacaaagctt aagtaagatt ttccacaagc acaatccaag atagttatac agtctttatc
   104941 ctttatttct tttaaaatac tatctatcaa ttcaacaaaa tggtctatct gattgtattt
   105001 tcttatttta tcatttttta tcttaccatc ttttgtaagt actccaattt cttttaaaag
   105061 tgcatttgct tgtcctactt ttacataata atctctgttt tttatttgag atgccgtaaa
   105121 ttcatctatt ttaggtactt cttccttatt atctaaatat tttacattta ccttcttatt
   105181 gtctccttca attacaacaa tagttcctcg ctcaacatat ttaaatacta atccatcata
   105241 attttctgcc tctttagaaa tattcttaag caactcatta aacgtatata aatctgattt
   105301 tcctttaaaa ttaaatttat atttattatc ttcctctatt gcaattcctt taaactcttt
   105361 tcttccagat ttaaaaatca cctctaactc aataaaaaaa tccctattat caaggtttct
   105421 ttgagtaatc cccataaaaa acatatttag ttttcctata ctctgtttat tcatcataat
   105481 ctccctttta acttatatcc ttaaatctta ttaattaata ttatttgttt ctgaattatt
   105541 tatttcttct tttaaatcgt tcaatctatt tttaaaactt tctatctgct tatctgataa
   105601 atcaagatat tctgttatct tccctatata tttagggctt ttagtattta ttaatttcaa
   105661 agcactttcc atagattttt ctctaagctc atatgctttc tttacgtcat ctctagcatt
   105721 actcaatgtt tctgtatact tctccttaga aagttctgga atctgcatat tttcatattc
   105781 ttttacaact tctttacact tgtttctggc atttgtaaca tcttttttta tactagataa
   105841 tttagttata ttttttgcta tatccttagt gtaaggtatg cattctctca ttggaactaa
   105901 agctgctctt tctatattat aaatttcttt cttaaaaatt cctatacttt ccatatctat
   105961 tttttttata tcttcactat ttttttcttt acttgtatat ttattatttt cttttgtatt
   106021 atcttcttgt ttttctgatt tattattcac tgaaacatta ctatcagaat tattcttttc
   106081 ttttatatca ttacttcctt cttcattact ttctttattt tgtatatttc tatcttgttt
   106141 gttgtttaaa tttttattat ttgatatttc ttcattcttt ttattatcct gttttaaatc
   106201 agtactttct ttttccttaa aatttgatac atacttttca tcatatgtct catcagaaat
   106261 ataattgtga taatacatag actcttttat tttattaagt ccactcatat aaatattact
   106321 tatcattatt gttgtagcta ataccacata aatactactg tagatacaag acctcttaaa
   106381 attcttgtaa tttctgaata tcactactaa aggaataaga tataaaaata taaaaactaa
   106441 tatccacctc ataagtcgtg tctcctttct caaaaccgaa atccctcaaa tatttatttt
   106501 taatcatgta tcttatagta tttaccaatt tatgtttttt aatcgtgaac ttttattaaa
   106561 ttaaattctg tatagtcaca agatgctaat gtatattcta ctccatttcg aatccccttc
   106621 aatcccattt taaaagattc tttaccatgc aagtgaccat aaatcacctt ttcaacatta
   106681 tattcttcaa ataactttgt aaataaagat tcttccaatt tatcattcgt aggaggataa
   106741 tgagtaatca caattatttt tgagtgacca cttttacgag cagattctaa tgatagtcta
   106801 agtctatgtt cttctctttt ataaactttt tcatcagtct catcaaattt gacatcatta
   106861 ggacatatcc agcccctacc tccacaaatt gcataatctt tatattcata aaaatttgtc
   106921 tgaataaaac gcatgtcttc atatagcttg tttaaacttg taacggttgt ccaccagtaa
   106981 tcatgatttc cttttataag tattttctga cctggaagtt tgcttattat atctaaatct
   107041 tttttagctt cggataaatt aattccccaa gatgtatctc ctagtactaa gaccatatct
   107101 tcttccttaa caacttcttt ccaattatct ataattttct tttcatgacc atcccaatta
   107161 cttccaaaga tattcattgg cttattgact gatgttgaaa aatgtaaatc acctatagca
   107221 tacaaactca taatatcctt cctttcttaa ttacactaaa taggctgtct ctttttagaa
   107281 attattttcc attaagaggc agccccatta atatttagca aattttctac aagtagtttt
   107341 tactgaacta ctttatcatc taccttagta tccttatatt gctctaataa tatatctatt
   107401 tcttgtttta attccaaaat ttcagttata tttttatctg tttcagttct atcaagtttt
   107461 ctttggtact gcatagcttt atgtgtatca cccaagtcat ataactcttg tattctattt
   107521 agagtatctc taatagctat agacttcatt tggtacatag cctgagcttt cattatgtcc
   107581 tctcttattt cactcatttc ttggtctaaa agaaaggcag catcagatgc tcttctaagc
   107641 ctttcagcaa gagtctcagg tatgtaatgg tcatatttat attttaatga atgttctatt
   107701 gtagcccaga aattcattgc aagagttctt atttgtattt cacatataat ttcctttgaa
   107761 cccgcaatgg agtttatagg gtattttatt ataacatgat agcttctata accactatct
   107821 ttgtaatttg taatataatc tttttctcct attatagtca tatcatttct tacttttatc
   107881 aaatcaacta tagcatatat atcctcaaca aactggcaca ttattcttat accagcaata
   107941 tcatcaattt cagtttctat atcttttgca tttatccttt ttaacttaga tattatggaa
   108001 gatatttttt ttgttctacc tgtgacaaac tctatgggag aatattcacc ttttgctaaa
   108061 tattcttttc ttatattttt aaattttatt ttcaattcct ctactgcatg ttcataaggt
   108121 gctagtatct cattccattt ttcgtattcc atattgctca ccctttattt gttttttatg
   108181 accttcttta ttttatcata atttattttg tttttgtata gtaaagcaat tctccatttt
   108241 ccaatatata ccctatttct tctaaatcaa ctaagtaact tatgacagat actaacgaag
   108301 atttaaaaaa atgatactct ttataattat tgcttaaatt attgttattt ataatgtttt
   108361 ttaataaaat ttctaaagat ttcggttcta caagcaactc tcttatttga tataaatatt
   108421 tttttaaagc attcaaatgt ttttctatta atttataaga atcttctttc gatataactt
   108481 gcttgccatg ccctaaaact aagtactcaa aatctatatt ttttaatttt tctaatgaat
   108541 ttatttgttc ttgtatatca tatagaaaca agaaatcgta ttttgataaa atttcatctc
   108601 ctatcaataa atcgccaaca aaaatcacat tatccttcgt caaaacagct atactaccag
   108661 gtgtatgacc ctgaaattca attatatcaa acatttcatt gtttaattca atttttccag
   108721 cttctataga tttatctatt tttatatcat ccaacatttt attttttaag atattatcca
   108781 taaatacatt gctctttccc ccaacaatat actttgaaaa caattctgga ttttctatat
   108841 ataatttatc gtattcagat gacattatac acacatcttt ataatattct ttaaattgat
   108901 tacaagctcc atagtggtca tcatgaccat gagtatttat aatatatcta acctgtatat
   108961 tattttcatc taatacttta tttactctcc taggtcttga accacataac cctgggtcta
   109021 tcataagtgc tgtgttatct tcaaatacat atattcctgt attcgtgcca ccttttataa
   109081 aaaaggtatt tccttttact tttgtaagat tcaccttctt cacctcattt tgacaatatt
   109141 tatgatacaa tttattactt actaatataa aactatacaa gaacaatcct ttttattcta
   109201 tctatagttc tttttcttat tttgtattct ttagatatcc ttattttcac attatatgct
   109261 aaatttctat aaagtaatga ctctataaaa tattcaacta tacctctatc cctaaagtct
   109321 atatctatat ttccacttga ataaatattt gagtctaata tcataagctc atcaaaaaag
   109381 cttaatctct tagatttact taaataatct ttatttggaa taaatctatc acaataatct
   109441 atcctgtaat ttactacttc atcatttatt tcaaatccat attgcttttt cattaactct
   109501 ctatagttat tatttttctc aataacatta tctaaatttt tattataatc ctcttttttc
   109561 caatgtccaa acatcctaca atttaatggt ctaacttcat atattaaaca tctattatta
   109621 gtatctttaa atggacatgg gttctttctt gtatactcct caaaataata atctaatatt
   109681 ttacttatac agcttttttt taaatcaact ctatcttcaa gataacaaaa tatattcaaa
   109741 aactcaatta aatttatacc tactgactcc atacaacaat ttccacatcc agaacaattt
   109801 cctactggca aggacttata tacatcattt agtttgtcaa agagcttatt tttaatggaa
   109861 taatctatac aatttaaaat atctttattt tttatactag tcattattat tactccttgt
   109921 tataattatt aagttaatac aaacaattat tataacatat tttttaaatt taatcgcata
   109981 tggaggtatt ttatgaatag atatacaaaa ataattaata tgatgggaag ttattacaca
   110041 aaagactttg aaaaagaaaa aaagaatgta ataaaagtta gagaagttaa agaagataca
   110101 gttagaaaat ttttcttaca aggtgactgt gaagttcttg tagtatttga agacactggg
   110161 aaagaaatac ttattgatga cttttctcct gaagaagata tcaaaaaata tttaggagca
   110221 aaatttataa ataaaaaaag atagttatca aaaataattc taaaattaaa atttaataaa
   110281 tgtacagtta taattctata taattatagt taaaagttat cttttattgc ttttttagac
   110341 tttaagatag ctttttttct attttttgta aaataattcc ataattcaca ttaataattc
   110401 acaaaatgat ataatataac aaatagataa attttaaatt tctaaataca taattaatat
   110461 tttgcgaggt gattttatgc aaatttattt tagagttaag gctgttggca aacgcaaacc
   110521 tatgctagaa cttacccctt ttgatgtacc tgacaacatc aattgcctaa aagaagctat
   110581 ctctgaaatt gtatctaaaa atgttcttga atataatgag aaaatcccag aaaaatcaat
   110641 aataaacttc ttaactaatg aagaaattga atctcaagct gatattggaa aagttggatt
   110701 tggctctatt tacaatgaga ataaacaatc tgtagaaaag gcaatagaag tagcgttaca
   110761 ggcatttgaa gatggaatct acaaagtgct tataaatgaa gatgttattg aaaaactcga
   110821 ttcctctata aatctgaaaa gtggagatat atttactttt ataagactta ccttgcttgc
   110881 tggaagaatg ttttaaaata aataatttgg aggtacataa atgttagaac gtactagagt
   110941 agaaaaaaat cctaaaataa ttgaaaattt taaaaataat tttactaaat cttcttcaaa
   111001 acagtactac gacttagcaa agtctctttg ggactgcata gaaaatagtt catactatta
   111061 tagagaacct gaagacaaat tcttaaatat gataaagaaa tactacaatt gccactacta
   111121 cgaaattaaa aatatggacg agctcctttc tggaccttta aaaaatgcat tagaattaat
   111181 atttacttct gaacaagtag aagaactttg ccaattaatt aaaagaaaga tggattatac
   111241 atattcagga ggatattatc gtaaagggta tcgctcaaat aaacttgtgg attattttag
   111301 aggtattata aggtttattt caaactatgt tgatttaatt tattatgatt tttcagttat
   111361 agattatctt actcttccaa ataaggtctt gtactatgac tctataatga gtgataaaat
   111421 agcactagaa atagacaaag gaaatcaaaa agtaataagt gctttagaag aagtaatatt
   111481 tggagaaaat caaactgctc tacttacaag acaaatgata attggtatca tgaagagtca
   111541 tagtgataaa tgctatgaaa tgctttctaa acttcttttg gcagccaaac aacaagaagg
   111601 acttagacag caaattgtag agagtttaga tgagggtaca atttctgcat caatatacat
   111661 gttaaaaact attttggaca acaatttaga gcgatttagt tctgttataa gagccttgga
   111721 tacatggaca ggacttggtt tttcagacca aaaacctgga ataatacgta aatgtttaga
   111781 actttcatat aaatcattga ctgatgaaaa gttccgtata gaatcaatta atagcaatga
   111841 taatcttgaa atttattttg ccttgtgggc tactgcaact tacaacatat atgactctta
   111901 ctctcttatt gaaaacttac tttcttgtca ggaaaaatat aaaaaacttg tagctcttta
   111961 ctttttatcg catacagaaa gtacatattt taaacattct atagcatcta aaaacattaa
   112021 gggtgatgat ttagagatac tagcatgggt aattacaaat ttctatgtag aaggttctgt
   112081 tggctactac tatagttggc aaaacagaga aactaatttt gacttgtcaa acactcctat
   112141 tgacaaagac tttgatgcta gaaaagaaca atttgaaagt ttaaaacata ctttagaaat
   112201 tttaaattca aagacaaaat cattttcagg aagtgtattt ccatggactt ggattgaaat
   112261 ttcttctcat gaaatactta aatgtatgat gactttaaca gcatacgata tgaatgctca
   112321 atttatagat gtgcttatgg aaaattgtca tcttatgagt tcagatttaa gagcttcact
   112381 tatagtcaat tttgtaaatg aaccaaagac agatagacaa cgtgaatttt tattggaatg
   112441 tttaagtgat aagagtgttt ccaatagaga aacggtattg agtctactta gaaagcttga
   112501 gctaacagat gtagaattag ataagataac caatctattg tctttaaaga caagctctat
   112561 tagacaaaca gtaataaaaa ttttacttga acaagatgat tcaaacttag aaaatattgc
   112621 ttcttcactg ataaaatctt caaattctca aaaatgcctt ggaggtcttg aaattgtaaa
   112681 cttattaaaa gacaatactg ctagacaaga actatataat aagcttgttt tacttataga
   112741 agatattgat aaatctaaaa agaatacatc tcaagttcaa atactaattg ataatttgtt
   112801 aggtaaagca aaaaatgatt actgcaaaga aaatggtttt ggaatatata accctgaaaa
   112861 caaagttcaa attccagaac aatttgattt taaagatgat tctaatagct catcaaagct
   112921 taataaaatt atctcaaata taagtttatc tactcgtgag gattctgttt ctgtagcaac
   112981 aaaaaaagaa gcaaaaaaaa ttctcgatac ggatataaat aaaataataa aagtttatga
   113041 aaaatttgat gagcttatta ctgaaaatgc agattatgaa tatgaagttg aaagatggtc
   113101 aggtaatgta gacaaagtac ttttaggtta ttctacttat aacttgactc ctattaaata
   113161 taaagtttct aatgatactc ttgataatta tccattagca gagctttgga gagaaactag
   113221 taaaaaactt gacttagatt acaaattaat acttgatatc ttattttata gtataagtac
   113281 atgtggatat aatgaaacag aaaaaagttg gttttcatct atatattcaa atgtccttga
   113341 ctctaaaaaa caaaataaaa tatatacaaa acttgaaaaa cttaaattta atggacttac
   113401 aagaaaactt ttaagagttt tactaaatga gtttgaccat aaagaaatat ttaactattg
   113461 tttagaaata tactataaac ttagaaactt attgactata gaacaatgta aaaaacaaag
   113521 agttgaattt actaaaaact attacagaca aaatgaatac tgccctgctt taaatgcccc
   113581 tattttaaac tattggcttg ataaagcaca ttcgtttatt tatgatgata tttcttttac
   113641 taagtttttc tacactacgt tttcaaatta tcagttgcta gaatataagt ttcctttcta
   113701 tactagcata aatgtgtttg ctcgtgcaca tgaattagga ttaatgactg aagagcaagt
   113761 taatagagaa atgataagtg gatacaacgc atcaaatata ataagaacat taacaaatcc
   113821 tagatgggct ggcgacacat tagaaaagta cccttggctt aaagataatt taaaaactgt
   113881 tacaaaccga attatagaaa ttgaatcacg tagaggtgat atgccaacag aagtgtctaa
   113941 tctagctaat aatatacaat actttgaagg tataaattat tttgtaaata ttttggtcgc
   114001 tcttggtaaa gaaactttcc agagaggata ttcatatggt agcaattatt caaaaaaaga
   114061 tgttttaagt tctctactta aaaattgcta tcctactaaa gaagatgact caaaaaaatt
   114121 aaaaagttta cttaaaaata ccgacattac tgagttaaga ttgatagaat ctgctatgta
   114181 tgcccctcaa tgggtaaaca taattgaaaa atatttaaac tggaagggtc tgaaaagtac
   114241 aatttggtac ttccatgcac atataaatga aggcttctct gcacaaaaag aatcagaggt
   114301 tgctctattc tcccctattt caccacgtag tttcattgat ggtgcatttg atgtagattg
   114361 gtttttagat tcatataaaa ctattgggga agaaagattc aatatacttt acaagtcagc
   114421 taaatatata actagtggtg gtaactctca tagacgtgca caactctatg ctgatgctac
   114481 acttggtaag cttgataaag acatgttgat gaaagaaatt gaaacaaata gaaatcaaga
   114541 taaattgaga agtttctctt tacttcctat gaaaaaagga gacctaaaag aagcaacttt
   114601 ccgttatgaa tttattcaaa agtttgctaa agaaagcaag caatttggtg cacaacgtcg
   114661 tgaaagtgaa tcaaaagctt gtactatagc gctagaaaat ctagctagaa gtgctggatt
   114721 tggagatgta aatcgtatga tgtgggctct tgagactgaa aaactaaatg aagttgctca
   114781 tctatttaaa ccaaaagata ttgatggtac ttcaatttgg atagatgttg atgaaaacgg
   114841 aaaagcatct actaaagttc aaaaaggcaa caagtcttta aagagtatac caaaagctat
   114901 tgctaaacat ccatatgtac ttgaacttaa atctgtccaa aaagatttaa agagtcagta
   114961 ttctcgtgca aaacagagtt tagaacaagc tatgaaaaat gaaatagtat ttacagttaa
   115021 agaaattgcc aatatctata aaaatccagt tatctgccct ttgattaaaa atctagtatg
   115081 ggtatgtgat gataatattg gatatgttta taatgataag tctaagttct ttatttgcaa
   115141 tataaaaggt gaaacttata agttgacggc aaaaaataaa ttaaaacttg cacatccagt
   115201 tcatttgttt gaatctggta agtggagtga gttccaacat gatttattta gtaagcaaat
   115261 tgttcaacca tttaagcaag tattccgtga gtattataga ataaatagtg atgaattatc
   115321 tgaaaaaact atatctcgca gatatgctgg tcaccaaatt cagccaaaga aaactgtagc
   115381 acttcttaga aatcagcttt ggactgtcga ttatgaagag ggattacaga aagtatttta
   115441 taaagaaaat atagtggcaa agatgtttgc acttgcagat tggttttcac cagcagatat
   115501 agagcctcct actattgaaa cagtagaatt ttttgataga aaaacttata aaagtttaga
   115561 attagcttct atacctccaa ttctattctc agaagttatg cgtgatatag accttgttgt
   115621 aagtgtcgct catgctggtg gtgttgaccc tgaaactagc cattctactg tagagatgcg
   115681 tatagcaatt gctaaagaac ttttattatt attaaaaatt aacaatgtca attttgaagg
   115741 ctctcatgct cttatagcag gtaatttagg tgagtattct gtgcatatgg gttctggtat
   115801 tgtacataaa aaagggatgg gtgctttgaa tatacttcct atacattctc aaagtagagg
   115861 taagatattc cttccattcg ctgatgaaga ccctaaaact gctgagatta tgtctaagat
   115921 actattactt gctgaagata gtaagattaa agaccctagt atcttaagta atttataagt
   115981 ataaaaacta tctctaaaat atattggact ttcttaaaaa aattagaaag tccaatatat
   116041 actatactgt aatttatata gattaaatca taattacaaa taatttttat ataaacttct
   116101 cttatacatt atctttacgg tacttattat atcacacaaa aagtattttt cttctatctt
   116161 cgctagaatc ttttaaccct ataaaatcta tataaaaaat ctttttctag agatttgttt
   116221 aatatggcat tttcttgaaa atttataaac cttatctcta atgaagattt atttataggt
   116281 ataaccttat gtataaatct tagatttact atgtattgtc tatgggtcat aaagaaatta
   116341 ggaggtaggc gtttttttaa atcatcaaag ttctcataaa actttattat atcttcatct
   116401 ttagtgtgta gattaattgc tcttgaattt ttctcaaaca taactatatc atcaaaatta
   116461 atcatatgta tctgcttcct tattttatat acaaaaaggg tgtcttctat aaaattatta
   116521 ttagcaatct tatgggagtt aatatggtct attgctatgt taattgaatc aagtattttt
   116581 tcttttttaa atggtttaac tacaaaatct ataggatgca ctttaaagct ttcaagacta
   116641 taatcagcga aacccgtcac aaatactata tgtatatcct tatctataga aagaatttct
   116701 tcagcagaat caatcccatt tttatatggc atatcaatgt caataatcaa taaatctatt
   116761 ttctcatttt ttataaattc aattgcctct ataccatcct taactttttt aacataatct
   116821 acatatccag actctttagc tatatttgct atatcatctc ttacaatctt atcatcatca
   116881 caaatcaaaa cttttatcat agacttttct cctcctaact aataatattt tgggattaag
   116941 attacaaatt cagttaaaaa atcatcacta tttacaagta tactataatc atacttatct
   117001 aatatatttt taactaaatg tagcccatat cccctatctt gtccttcttt agtactaaat
   117061 ccattccaaa atatactttc aacattatgt attttaggac cattattttt tatagctata
   117121 atatactgaa attcatcttc atatgcatgt aatcttatat acttcttttc tttttttata
   117181 gtagacaaag actctattgc attatctatt atgtttaata gtactgaact catatcatta
   117241 ggttcaatct ctaaattatc cataaaatct tgaatgtaga catcaaaaga tatatccttt
   117301 tcaagacatt cctcgtattt taatgaagct atagcatcta aataagatac ttttccatac
   117361 cttgaatttt ttgatttaaa gctatttgat atattcatta tatattcttt ggcatcttca
   117421 tctagcccag tatttaatag agaatacact acttgcaaat gtttcaaata gtcatgtttt
   117481 tgacttctta atttgataat tatattatcc ttatgattta ttttactatc tagtttttgt
   117541 aatttatatt cctgttcatt attattattt atcaatctta taactttaaa gcctgtataa
   117601 aaacttaaaa taattaaaac caaaaaaagt ataatattta atactccttc aagtaaaaaa
   117661 ctatatccta accttaattg tatatattta gtgccctcca taaataaaat caatgcaaaa
   117721 cacgatataa aaaatgttaa tatgcctctt tttaatatgt ctaattcttt gtaaaattta
   117781 tacttattca ttataagatt gctaaatata aacaaagtta gtattactat aggaaataca
   117841 aaattgttat ccatgattcc cctcccctct acaatttata tagggattat atcattttaa
   117901 aaaaattatg taaaaagtta aaatttacat atatattaat taaacttgta aaaatacaga
   117961 tgaatttgta caattaacta cttaaaactt gaaaatactt actttgctat atattttaga
   118021 taaatatata attgatttag ttaagaaagg aagtggtaaa tatgaaagat aatttgaaaa
   118081 tagtactaag gtatataaaa agttataaag ctaggtcttt agcaattgtt gtgagtataa
   118141 ttcttgctac atcactcgtt gttggtattg gtaccctctc aagaagtgct cagcaagcag
   118201 atgtagatag attgaaaaga gagcttggaa ctgaccatgt atactttaaa aatataaaga
   118261 aaaatcaatt aaagtccata aaatctagca aagatattaa aaatctgggt ataacatctt
   118321 actatgcgtc tacagatgtt aatgaaaaat tacctataaa catactatat gcaaataaaa
   118381 attatttgac tagtcattct aaacttataa aaggtcgatt tccaaaagct agcaatgagg
   118441 tggtagtcga gaaatggatt ttaaatagta tgggcttaaa accagagata aatcaaaacc
   118501 ttacttttaa attatatcaa aaagaaaatc cagaaacttt taaagttgtt ggaatccttg
   118561 aagatagatt tatagagaaa aaaaagggac aatgtgaaat tttttctaat ctcaatgaat
   118621 cagaactgaa tgattttaca acttatattg aatttaatga aggcagtgat ataaatacaa
   118681 acatagacaa tataataaaa aatgctatgt tagatgagaa aagtatagga agaaactcaa
   118741 tgcttataga atctactatg aaaaacggta ctttagataa ttcaagtaaa tacgttgcaa
   118801 ttgctatgag tctatttgct ggtattgtaa tatatagtat ctatgttata tcaatatacc
   118861 aaagagtata ggaatatggc gtcttaagag ctattggttc caccaacttt aggattttca
   118921 aacttatgct ttatgaactt ttcatactta ctctaatagc aatgcctata ggtatatgta
   118981 taggtatggg aggtgcacaa atatttaata ggtctgtagg aaatattcaa tttgaaggaa
   119041 atataaatgt tacacctttt gttattccag ataaaataat tctcttatca attgcatgta
   119101 caatactaat aatactaatt ataagtttct ttacatactt aaaaataaga agaatttctc
   119161 ctattgatgc tatcagaaaa acttttggag ctgataaaaa tgtaaccaaa gttaattatt
   119221 taatatcaaa attaacttta aatatgtcag taacaaaatc tatatctgcg aaaaacatct
   119281 ttagaaataa aaaggggttc attataattg tattatctat gagtatagga ggtataatcg
   119341 tcataaaaga caattataaa tattcttttt tagatgtgca aaacaaatct actcaagaac
   119401 aaacatatat gaatgcagat tttattctat caaatgttta tctcaatgaa attggtaaca
   119461 atacttcttt taaagatata aaagggttta atgataatca gatagataaa ataaaaaata
   119521 tagatggaat tgacaaagtc aaaactgcta gtatcttaaa cacaagaata gaggtaaata
   119581 aaataaatag attagattac tatgaagcta taaattcaac tccttattat aagctaaatc
   119641 ctctgttcat aaaaaataag actactggca aatatacact aaagcaaaag ctaaaaggtt
   119701 ataatgatga gatgataaag tcattagaaa aatacttagt aagtggaaat ataaacttga
   119761 aaaaaatgaa aaaagaaaat ttagctattg tatatgtacc agaaatttct aaaacacaga
   119821 aatacacaaa gacttttact cctggtgaag gaacaccagc tgtagatata aaagtaggtg
   119881 atactataaa agtcaaatat ccaaagggtg ggatggatac aggtctttat gaaagtctaa
   119941 aagataatta tgaatactta gaatatgaat ttaaagttgg agctattata agttatcctt
   120001 ttgcagataa tggtatgtac tctggagatg atggtgtaga tgtaataacg agtagcgaat
   120061 acctaaaaaa attaactggt gtagataagt ataacttagt ttatgcagac cttaatgaaa
   120121 atgcaaacaa gaaaaaaata aataaccttt taggtaaaat tggaagtgaa gttcctggaa
   120181 ctacaacagt agatatgatg gtagaaaaag aaaattctga taagatgaca tctagaacta
   120241 tgatttatag ttatggtata gtagcaataa tgttcataat cagtgtactt aacataataa
   120301 acaacataag ttataactta acttcaagaa ctagtgaatt tggaatgtta agagctattg
   120361 gtatctctga gagaggcttt aaaaatatga tactttatga aggaatatta tatggtgtac
   120421 tctcaagtat aattactatc gtgtcaggaa ttataataca atttaaaatg tattatatgc
   120481 agggctttgt atcatatgga ttgggatttt caatagatta caaaatatat atactagttg
   120541 ttgtagcaaa tataattgta ggtattctag ctacatatat tccatcaaga aagataaata
   120601 aaattagtat agttgaagct ataaacatta cagaatagga ggaataatta tgcctatatt
   120661 ggaaactatt aacttaggta agatttatgg aaaaaaggaa acatctgtac atgcactaaa
   120721 gaatgcaaat ttaaaaataa ataaaggcga atttgttgct ataattggac caagtggaag
   120781 tgggaaaagt acatttctac atttagtagg tggtcttgaa agaccaagta atggtactat
   120841 aaaggtagat ggtaaagata tatgttgtct ttcagataaa gaattagcaa gatatagaag
   120901 acaaaaggta ggatttgtct ttcaacagta taacttaatt cctgtattaa atgtaaagga
   120961 aaatatagaa ttaccactaa agttagacaa taaaaaaata gataaagaat atattgatga
   121021 ccttataaat ttattgggtc ttaatgaaag gaaaaatcat cttcccaacc aattatctgg
   121081 tggtcaacag caaagagttg ctattgcacg tgctttatct gcaaaaccaa gtataatcct
   121141 agcagatgaa ccaacaggaa atttggacag taaaactaca gaagaagtca tggatttact
   121201 aaaaagttct ataaaaaaat ataaccaaac ccttataata ataacacata atgaaaatat
   121261 tgctagaaaa gcagatagaa ttatatctat aatagatgga gagcttaaat taacactcta
   121321 aaactattta tagaaaagag gatttaaatg ttattgattt taggtaattt aaatttaaac
   121381 ttggattttg actacagaat aataagagaa gaaaatgatg atgtagatat atttatagat
   121441 attaattatc gtagcttaga tatagatact gatggttcta acttatttaa ttctagaata
   121501 caatttccat ttgtaagagc attgattcta aggctaaata agaacaatca atgtatgaca
   121561 attcatttgt taagagatat agatttattc tctgcttttg ccaactttga agtggattat
   121621 actgactcta taataaatat aaaaaatcaa aatgagaaag taattttaaa taaatctatc
   121681 aaaaaatagt aagggggcct taataggccc caattttttt cttttctaaa cttattatat
   121741 catgataaat aaattagtca atagaatttt ctgaatattt ttataatttt ttcataaagt
   121801 tttttatata ttatgcttta aaattatatg taataaaaaa attttccgac taattttaaa
   121861 gttaattgat taaatacaca tattcgaaat taccattaaa ttactgactt tttatcattt
   121921 ccatttagaa tttaaattat aatctattat ttatagttac ttctacgtgt ctctaataaa
   121981 actctattta tattcaaatc taataattta tatacaaacc caatagaacc tatgttgcac
   122041 aatagatatt atttaccata ataaactttt agatatatct cttttaattc actcatcaat
   122101 gggtatctag gattagcacc tgtacattgg tcatcaaaag cttgttcaac catagcatcc
   122161 aatctttcta agaatttaga ttcttctact ccagcctctt ttatagtctt aggaagacct
   122221 acttttgcct ttagttcatc tattgctttt ataagattat ctactttttc ttggtctgta
   122281 cttcctttaa tacctgcaaa agaagcaaat tcagcatatc tttgtatgca atcaggatat
   122341 ctgtattgtg agaatgcacc cattttattt ggagcttctg cacaattgaa cttgattact
   122401 tcatttatta ataatgcatt tgcaacaccg tgttgaacat ggtggaatgc acctaattta
   122461 tgtgctaaag agtgacatat tcctaagaag gcatttgcaa aagacattcc tgccatagta
   122521 gatgccattg ccattttttc tcttgcttct ttatcattct ttccattttt atatgcacga
   122581 ggtaaatatt caaatattat tttacctgct tgtagtgcta gaccgtcagc tggttcagtt
   122641 cttaacatag atacatatgc ttctaatgca tgtgttaaag catcaacacc tgatgctgct
   122701 gttaatcttg gtggcatctc catcatcata tcagcatcaa ttatagccat gtttggcatt
   122761 aattcataat ctgctaatgg gtactttaca cctgaatctt ggtcagttat aactgcaaat
   122821 ggagttactt ctgaaccagt tcctgctgaa gttgggatag cagcaaaata cgctttttca
   122881 cccatcttag gaaatacata tactcttttt cttatatcca taaatctcat agctaagtct
   122941 tggaaatcta cttctggatg ctcatacatt acccacatta tcttaccagc atccattgca
   123001 cttcctccac ctacagctat tattaaatct ggttggaaat cagccatagc tttagctcct
   123061 tctcttgcac aagctaatgt tgggtctgga gctacatcaa agaatgtagt atgcttaatt
   123121 cccatctcat ctaataaatc agttaatttc ttagtatatc cattattata taggaaagaa
   123181 tctgttacta taaatgcttt ctttttatcc ataacatcct taaattctct tgctgctaca
   123241 cctaaacatc cttttttgaa ataaaccttt tctggtgctc tgaaccaaag catattctct
   123301 ctcctttcag ctactgtctt gatattaagc aaatgtttta ctccaacgtt ttcagatact
   123361 gagtttccac cccaagaacc acaaccaaga gtaagagacg gtgccaattt aaagttatat
   123421 aaatcaccta taccaccttg tgatgatgga gtattaacta atactctaca agtcttcata
   123481 gcatttacaa acttttctac tctctctgga tgatttatag agtctgcata taatgaagat
   123541 gtatgaccat agcctccatc tgcaactaat ttttctgctt tagcaactgc atcttcaaaa
   123601 cttttagact tgtacattgc aagtacagga gaaagttttt catgtgcaaa aggttcattt
   123661 aattcaacag attctacttc accaattatt attctagctg tttttggaac ttctacatcc
   123721 gccattttgg ctattacatg tgctggttgt ccaactattc tggcatttaa tgaaccatca
   123781 attattacta cttttcctac tttttcagtt tcttctttat ttaggaaatg tgctccacga
   123841 tatttaaatt cttttttaac ttcttcatat attttttctg gtactattac agcttgctcg
   123901 gaagcacata tcataccatt atcgaatgat tttgatacta agattgaact tacagccatt
   123961 tttatatctg cactctcatc tattattgca ggtacatttc caggcccaac tccgacagct
   124021 ggtttacctg aagagtatgc agatttaacc attccaggtc caccagtagc taatataagg
   124081 tctgcctctg ccatgacaac attagttaat tcaatcgaag gaacatctac ccaacctata
   124141 agtccttttg gtgctcctgc cttaactgct gcatcatgta caactctagc tgcttctata
   124201 gtacagtttt tagctcttgg atgaggagag aaaattatac catttctagt ttttagtgct
   124261 attagggatt tgaatattgc agttgatgta ggattagttg ttggtataac tgctgataaa
   124321 acacctactg gctcagcaat tcttgtaaaa ccaaatgctt catctttttc tatgacacca
   124381 caagttttag tatctttata agcattatag atatattctg aggcaaaatg gttttttata
   124441 accttatctt caacaatacc cataccagtc tcttccactg ccatttttgc tagaggtatt
   124501 ctttgttgat tagctgcagt tgaagcagct aagaaaatct tatctacctg ttcttgcgta
   124561 aatgttgcaa attctttttg tgccaatcta atttcttcta atctcattct taatgtttca
   124621 acactgttga caatttcagg actacatact tcaacatttg atttttctac taccttttct
   124681 tttttctcca tactaaaaac ctccctaaaa taattatgca tctctaattt ttataaatct
   124741 taaatgcatc atctatattt ttaacttata cttaaaataa ttttatagat ttcatctcta
   124801 taccttagat tttatttatt ttactctctt aggtcaagaa gtttttttct gaatattttg
   124861 tcaatttatt ttttaacaaa tatattattt tttttacttt tactaaaatt ttttatctaa
   124921 atgagatata tttcatttga ataatttact tcgactaaat aaaatactaa aatgataatt
   124981 tatatctttc atttttttta cttattaaat tttatatgtt atttgcatgt tatttgtata
   125041 agtagtaaat aaaatttttg tcgtattttt ataaaataac acttattttt gacttgtatg
   125101 caatttttct ttttataaca actgtatagt tttaaaaaat atataaacta aaattattct
   125161 aatctctata agttattttt aagtcaatat gtaataatta tgcttttcat atagataaat
   125221 aatttttata ttaagaccgt taatttttta atgataatat atatacaaaa ttttttacag
   125281 tataaaatat ttataaattt ttaatttatt aacatattaa ttaatttttt cccaggtaga
   125341 tttaatcaat ttattttaaa taaaagtaaa tttaattcga tatttgattg ggtaaaagta
   125401 tatataataa taatttttat attaaatttg tagtatttat gtaagaaata aattttatat
   125461 aatatttttt cactaaattt ttttcttttt acaacaaata ctcactacct tttgatataa
   125521 tatttttatc aattattatt atattcaagt tttgaaagga gtattaaaat gagtttatta
   125581 gttttcggac ataaaaatcc agatacagat tcaatatgtt ctgcaatttc attagcacat
   125641 ttaaagaaca aactaggaat aaaagcaaca gcttatgctt taggagatat cagaaaagaa
   125701 gctaaatatg ccttggatta ctttaaggta gatgcacctg aaattttaga taatgttaga
   125761 atacaagtta gagatttaaa ttatgataaa gtagtacctt taacaccaac ttcatctata
   125821 ttagaggctt ataaccttat ggatgaaaaa aatgttaaaa cactacctgt aacttatgat
   125881 gatggaactt ttgctggtat cattactatg aaagaaatag ctaaaaatct acttcatcaa
   125941 cactttacaa ctatacacac atcactatca aacatttgta aaaaccttaa tggtactatt
   126001 cttgtggact gtggtgaaga tataaaaggt agagtagtca ctttatcatt tggaatggag
   126061 actctaatag agactttaaa agaaggagac atagctattg ttggagatag atatgatagt
   126121 attgaatatg ctattgatac aaaagttaaa cttttaatac ttactaatca tacagagatt
   126181 tcaaaagatt tgctagctct tgctaagata aatggagtgt ctgttgtttc tgttgaaagt
   126241 gacaattata aaacttctaa tgtaataaat caatgtagtt tcttagactc tatagaagct
   126301 acagaaaatt taattacatt caaagaagat gattatatgg atgaaataaa agagattatg
   126361 ctagaaacaa acttcagatc ttatccaata ttagatgatg ataataagtt tttaggttta
   126421 gtttcaaaag gtcatctatt aaacccatct aaaaagaatg ttgttttagt tgaccataac
   126481 gaatatgctc aaagtgctga tggaattgaa caagcaaaca tagttgaaat aattgaccat
   126541 cataaacttg gtggtatttc tactgatgtt cctatgtcat ttagagttat gcctgttgga
   126601 tgcaatagta ctataattta tcaaatgtac aaagaaaata atgttgagat accttatgaa
   126661 atagctgggc ttcttttatc tgctatatta tcagatacat tattatttaa gtctccaaca
   126721 acaactgata tagataagaa agcttgtgaa gaattaagta aaatagcaaa agtagacatg
   126781 gaaaaatacg ctatggatat gtttaaatgc ggtacttctt tagatgaata tactatagaa
   126841 gaaatagtaa atatggactt taaagaattt aatatgagtg gacatagagt tggtattgga
   126901 caagtattta ccttagacat agactctata tttgctaaaa aagatgagtt tttatcttat
   126961 ataaattcga ctgattatga taaattaatt ctttcagtta cagatataat caaagaaggt
   127021 tcttatttaa tctataaagc agaagatagc ttaattgcta acgcatttgg tgttgaaggt
   127081 gttcaaggca catttgcacc aggtgttgta tcaagaaaaa aacaattagt ccctaattta
   127141 actactgcaa tcaaaaattt taaataatat aaaattttta aataacgaaa actgtctcaa
   127201 atctatattt gagacagttt tttattatat atatattgat aataaagtta aataaaaatc
   127261 cataaattta aaatttttat gaatatattt tattattatt gttattttat tcattctaaa
   127321 ataggtaaaa ctcaatatat aaaaatactt ttgtcattta aataaagcct aaatagtttt
   127381 taagattatt ttagacacgt tttaagtcat aacagtatca gctattctaa atatcgtcaa
   127441 agtagccgca gttcctgctg attgcccatt tcgtatccct actgttgtag atgaaaaatt
   127501 atttattgta aaagtagtcc caccaaataa aaaaccagca aaatatccag aaagtactcc
   127561 tccgcctcct ggctcagtag taagccctgc caaatctttt cctcctaaaa ttgggaatag
   127621 gatagcgaaa gaatattgat ttatacttga tgaacctggt tgtaatgcta ctgaaactga
   127681 tatataatac acaccatttt cttgtactgt aaacgtacca tttgcatcta ctgttatact
   127741 tgaactattt cctattattg tttgccaacc tgttatagca tctccattat ttagtgtttg
   127801 tggagatggt gcatttacga ggaagttagc aactggctga gaggaattac ctgttgctcc
   127861 tgttggtccc gttggtccta tacttcctgt cgctcctgtt ggacctgtta ctcccgttgg
   127921 ccctatactt cctgtcgctc ctgtatttcc tgttggtcct gttgctcccg ttggtcctat
   127981 ttctcctgtt gggcctgtta ctcccattgg tcctatactt cctgtcactc ctgttgggcc
   128041 tgttggacct attgctccca ttggtcctat acttcctgtc actcctgttg ggcctgttgg
   128101 tcctatttct cctgtcactc ctgtcgctcc tgttgggcct gttactcccg ttggtcctat
   128161 acttcctgtt gctcctgttg ggcctgttac tcctgttggg cctgttggtc ctatttctcc
   128221 tgtcactcct gtcgctcctg ttgggcctgt tactcccgtt ggtcctatac ttcctgttgc
   128281 tcctgttggg cctgttgctc ccgttgggcc tgttactccc gttgggccta tttctcctgt
   128341 cactcctgta tttcctgtcg gtcctgttgc tcccgttggc cctatacttc ctgtcactcc
   128401 tgttgggcct gttggaccgg ttgctcccgt tgggcctgtt gctcctgttg gccctatttc
   128461 tcccgttggt cctatacttc ctgtcactcc tgttgggcct gttactcctg ttggacct
//
LOCUS       DAFAZV010000006       126333 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFAZV010000006 DAFAZV010000000
VERSION     DAFAZV010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 126333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 126333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..126333
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.006"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(183..377)
                     /locus_tag="KOU88_000664"
     CDS             complement(183..377)
                     /locus_tag="KOU88_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210577.1"
                     /translation="MFQVINFLCLFCVGFLVLDVMIYFCKDAMDIFEGTTNVNKVKSI
                     NVWADRVRANSYSYENKIAK"
     gene            complement(683..2212)
                     /gene="lysS"
                     /locus_tag="KOU88_000665"
     CDS             complement(683..2212)
                     /gene="lysS"
                     /locus_tag="KOU88_000665"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBK3210578.1"
                     /translation="MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRY
                     DRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKAGFIDIQDQEGRIQSYVRLDAIG
                     EEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
                     LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARP
                     FITNHNTLHIPMYLRIANELYLKRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIEL
                     YQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPWKRMSMEDCVKEYSG
                     VDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEV
                     SPLSKRNVEDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAF
                     EMDEDFLKALEVGLPPTGGLGIGIDRVIMLLTNSPSIRDVLLFPTMKPIDNNPNKEEE
                     N"
     gene            complement(2227..2706)
                     /gene="greA"
                     /locus_tag="KOU88_000666"
     CDS             complement(2227..2706)
                     /gene="greA"
                     /locus_tag="KOU88_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBK3210579.1"
                     /translation="MEENKEFLLTQEGYDKLEEELENLKVVKRKEVAERIKVAISFGD
                     LSENAEYDEAKKEQAQVEERILKLENMVRKAVIIDESKIDLNVVTIGSIVKVKDLEFD
                     EEVEYTIVGSTEADPYDGKISNESPVGKALLGRAAKEVVEVQVPDGVAKFEILEIRR"
     gene            complement(2815..3783)
                     /gene="dusB"
                     /locus_tag="KOU88_000667"
     CDS             complement(2815..3783)
                     /gene="dusB"
                     /locus_tag="KOU88_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBK3210580.1"
                     /translation="MKIGNLELKNKVFLSPMAGVTDLPFRLICKEQGCGLLYTEMING
                     KALCYDDENTKKMLKIEEEEHPVAVQIFGSEPEFMGRAAEIMNDYSNEILDINMGCPA
                     PKVVKNGDGSALMKNPKLAEEVLRAVVKNSKKPVTLKIRKGWDDNSVNAVEIAKIAED
                     CGISALAIHGRTREQFYTGKADWDIIAEIKKNLSIPVIGNGDVFTIEDSINMLDKTGC
                     DAIMIGRGAQGNPWIFKRINHYMNTGEILPEPTLNEKISTAIKHLKLAVEEHGEYVAV
                     REMRKHIAWYLKGLRNSAKLRDEINKIEDYQEVVSKLEYYMEDSLT"
     gene            complement(3920..4690)
                     /locus_tag="KOU88_000668"
     CDS             complement(3920..4690)
                     /locus_tag="KOU88_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III pantothenate kinase"
                     /protein_id="HBK3210581.1"
                     /translation="MLLVFDVGNTNMVLGIYKGDKLVNYWRIKTDREKTSDEYGILIS
                     NLFDYDNVNISDIDDVIISSVVPNVMHSLENFCIKYCKKQPLIVGPGIKTGLNIKYDN
                     PKQVGADRIVNAVAGIEKYGAPSILVDFGTATTFCAISEKGEYLGGTIAPGIKISSEA
                     LFQSASKLPRVELAKPGMTICKSTVSAMQSGIIYGYVGLVDKIISMMKKELNCDDVKV
                     IATGGLAKLIASETKSIDYVDGFLTLEGLRIIYEKNQE"
     gene            complement(4709..5299)
                     /locus_tag="KOU88_000669"
     CDS             complement(4709..5299)
                     /locus_tag="KOU88_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK3210582.1"
                     /translation="MMNTSASVRKVNVRKMTIIGVLSAISIMLSMTPLGFIPVGPTKA
                     TIMHIPVIIGAIMEGPIVGAAIGFIFGISSLLNAITNPTVTSFVFINPLVSILPRVMI
                     GVLAYYVYQLIIKATNKVYISGLITGAIGSLLNTAGVLGMIYVLYADKYLHAMGKSGS
                     AGKVIMALAAANGVPEAIVGALVVAAVATVLKKSKK"
     gene            complement(5483..6451)
                     /locus_tag="KOU88_000670"
     CDS             complement(5483..6451)
                     /locus_tag="KOU88_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P1 family peptidase"
                     /protein_id="HBK3210583.1"
                     /translation="MYNNILDIEGLKVGQIEDRNGLTGCTVVICEEGATCGVDVRGSA
                     PGTRETDLLDPVNMVQKVHAVVLAGGSAYGLESTCGVSRYLEEKGIGFDVGVGKVPIV
                     VGAVLFDLGVGSFKCRPDLKMGYRACEVANTDILNQGNYGAGCGATVGKIRGQEYAMK
                     GGIGSYSIKLDNGLIVSALIAVNALGDVYENGKVIAGALNDKRTETIDTYKLMKQGES
                     KGGFSVDNTTIGIIATNAKLTKAGCKKISQMGHDGYAKSIFPIHTPHDGDTIFTISTG
                     EIEADITLVGSLAVEVVEKSIINAVKKADSVENIMAYKDIVKKREI"
     gene            complement(6444..7421)
                     /locus_tag="KOU88_000671"
     CDS             complement(6444..7421)
                     /locus_tag="KOU88_000671"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBK3210584.1"
                     /translation="MRDKIIEIILNNKSEFISGEELSKQLGVSRAAIWKHMKALKEEG
                     YNIESVNKKGYRLAENPTDLLSPQNIYYKLDTDFIGKNIEHLDTIDSTNEHAKRIAIN
                     SVDGTVILSEHQDMGKGRLGRRWNSKPHEGIWMSIILKPDMEPFKAPFITLIAGASVT
                     KALNNLGANTLIKWPNDVILNGKKICGILTELSAEIERTNYVVLGIGINVKIMDFEQE
                     IADKATSLYKEGYMLSRVDIVRNVLTEFEKLYLDYTVNNSKEKTLKICRDYSAIIDKN
                     IYVLKGDNRELVKCLDINEEGNLLVQRSDGSIKEIISGEVSIRGEKGYV"
     gene            complement(7736..9706)
                     /gene="ftsH"
                     /locus_tag="KOU88_000672"
     CDS             complement(7736..9706)
                     /gene="ftsH"
                     /locus_tag="KOU88_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBK3210585.1"
                     /translation="MNKLLKGAGFYLLVFIIIVGIVQFSGKPTEKIKDLKFSEVYREL
                     TDENISRLYFVNQTSVEGTIKDTNTKFKSYVPTEVMGNKLADEVLDQAKAGKLTFGGE
                     AKPSTPWFVEMLPTLLLIFFMVIIWFVFMNQSQGGGGKVMSFGKSKAKVHKDDEKTRV
                     TFKDVAGLDEEKEDLQEVVDFLKNPKKYIELGARIPKGMLMVGPPGTGKTYLSRAVAG
                     EAGVPFFSISGSDFVEMFVGVGASRVRDLFEQAKKSAPAIIFIDEIDAVGRKRGAGLG
                     GGHDEREQTLNQLLVEMDGFGVNQGIIIMAATNRPDILDPALLRPGRFDRQVVVGTPD
                     VKGREAIFKVHSRNKPLSDDVKMDVLARRTPGFTPADIENLMNEAAILTARKREKKIK
                     METIEEAITKVIAGVAKKSKVISEKERRLTAYHEGGHAVCAHVLEEVSPVHQVTIVPR
                     GRAGGFTMQLPVEDKFYATKNEMKENIVVLLGGRVAEELVLKDVSTGASNDLERVTAT
                     ARSMVTKYGMSSKLGPMSFDSDDEVFLGNSFSSKRNYSEEVAFEIDQETKRIVDGAYD
                     KTRSILQENMDRLEYVAQALLIYETLDAEQFVKAFNKELPLNEIENAVTEENSSKEVE
                     EQLTIKLEKDEEERNNVIDINKNLEDKSDKDK"
     gene            complement(9740..11128)
                     /gene="tilS"
                     /locus_tag="KOU88_000673"
     CDS             complement(9740..11128)
                     /gene="tilS"
                     /locus_tag="KOU88_000673"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBK3210586.1"
                     /translation="MIFDKVLSTINKHNLIQKGDKIVLGLSGGPDSVCLLHVLNRLKK
                     DFNIEIYAAHLNHQIRGIEAQKDALYVSKLCEDMGIIFFVKSINVPKYCENEGLSLEE
                     GARKLRYEMFYEIKDKIKANKIAIGHNLNDQAETVMMRIMRGTGLKGLKGIDYIRDNC
                     IIRPILDVERNEIEEYCEAYNLNPRIDKTNLENIYTRNKIRLDLLPYMKDNFNSNVIE
                     SIVRMSNSLKSDNDYIEKEAEAKFREVSNIKEKGFVEINLDDFVCLHDAIKVRVLRNS
                     IKHILGDTNFVDQRHIEDIMSLEDNSKVNKMLTLPRNIFVYRKKDSIILTNEEIVNEE
                     IEFYYNVPSNGFIKIKELKQIIETQVMSIDRYKSMKLDNSSKGFDFNKVKGGIVIRSR
                     RQGDKIKLAMGSKKVKDLFIDLKIPREERCKIPIITDSEGIICVGDYKISENYKIDEN
                     TKEVLKINFNKL"
     gene            complement(11311..11739)
                     /locus_tag="KOU88_000674"
     CDS             complement(11311..11739)
                     /locus_tag="KOU88_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBK3210587.1"
                     /translation="MEEKSLSVKISINTRQYDEKGNMDTIEMTAFGKIFYKNDGIYVI
                     YKEKEENIEITNTIKILKNQVSIKKFGAINSTMLFKCGESSTTKYVTPQGTLLIDIDT
                     RELDINIQEGEHIKLKIDYNIKVQDLFLGRNKIDIYIGTK"
     gene            complement(11756..12562)
                     /locus_tag="KOU88_000675"
     CDS             complement(11756..12562)
                     /locus_tag="KOU88_000675"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBK3210588.1"
                     /translation="MNNKPIGVFDSGLGGLTVLKEIMKILPNEDIIYFGDTARIPYGS
                     RSKETIIKYTFQAINFLKTKGVKAIVIACNTATARSLKEAQEKYDIPIIGVIEAGART
                     AVSSTKNKIVGIIGTEGTISSKAYNLEISKIDESIEIVNKACPLFVPIVEEGWANTEV
                     AKLTAKIYLQELKEKNIDSLVLGCTHYPILKRTIGEEVGEHIKLVNPAKETAKDLKKI
                     LEVQNIINNTEIHGTYQYYVSDIPEKFSDIAREFLKKKIDKIQKVEIQKY"
     gene            complement(12764..13249)
                     /locus_tag="KOU88_000676"
     CDS             complement(12764..13249)
                     /locus_tag="KOU88_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBK3210589.1"
                     /translation="MATLLALTFIFMPIKEVFAYEPTENIKKVNKQEKNIAKKEVINL
                     SDNDLMLLSKLVAGEARGESYEGQVAVAAVVINRVLDPRFPDTIEEVIYQKNAFSVVL
                     DGSIKMAPTDSARKAAQEALYGTDPTNKAVYFWNPEIATCKWINRLNPYMRIGNHVFA
                     K"
     gene            complement(13300..13959)
                     /gene="spoIIR"
                     /locus_tag="KOU88_000677"
     CDS             complement(13300..13959)
                     /gene="spoIIR"
                     /locus_tag="KOU88_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBK3210590.1"
                     /translation="MRKIKIRLGLLILSLISVISIMTIVINGEVKKVDNISKDYKDKL
                     IRFHVIANSNTDEDQELKLKVRDEVIKYLQPKLQNSKSIKESEAIIKKEYSSLEEISK
                     NIILKNGYNYSVKVGIQYSNFPTKQYSNIVLPAGEYKALKIIIGKGEGKNWWCVMFPP
                     LCFVDESNGVIDKSTDDKLKEVLTDKEYKLIKQDTPKKTSRVKIKFKVLEVVKDLEKK
                     F"
     gene            complement(14104..14784)
                     /locus_tag="KOU88_000678"
     CDS             complement(14104..14784)
                     /locus_tag="KOU88_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3210591.1"
                     /translation="MENLTKLNLDNYKPLRDVVFENLREAILEGKLKPGQRLMEVQLA
                     EQLGVSRTPVREAIRKLELEGLVVMLPRKGAYVANMSLKDIMDVLEVRASLEGLAAYL
                     AAERISDEDIKKLKDISEEFKKSTLESDVDALLKLDVEFHECIFKATNNKKLIQLINS
                     LWEQVYRFRVTYMSAYDTSHNIVEEHKYLLDAIIKGDSELSKKYATEHIEKAEQFMID
                     KAMISKDL"
     gene            complement(14768..15658)
                     /locus_tag="KOU88_000679"
     CDS             complement(14768..15658)
                     /locus_tag="KOU88_000679"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBK3210592.1"
                     /translation="MDFIRLKSRAKINLSIDVLGKRQDGYHFVEMIMQTIDLYDIVKI
                     KELDEDEIKVKSTSLDIPLDEDNIVYKAAKILKNKFYIKKGVEIFIEKNIPVAAGMAG
                     GSSNAAAVLVGLNHLWELRLSEDELKEIGLNLGADVPFCISGRPALAQGIGEKLTNIK
                     GLPCDTNILICKPDLFVSTKEVYQGLDLNNIKKRPNNKYLIECLKSEDIKAVSESMVN
                     ILENVTIGKHKEISDIKQVMMKNNALGSMMSGSGPTVFGLFKNKEDALIGKKELLKKY
                     KQVYVVNSSQKGVEICGEFN"
     gene            complement(15776..17326)
                     /locus_tag="KOU88_000680"
     CDS             complement(15776..17326)
                     /locus_tag="KOU88_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3794 domain-containing protein"
                     /protein_id="HBK3210593.1"
                     /translation="MELIKDVIKVDNRIDFGKFQTFIEAEAVVPDKKLDVYEIVKTEG
                     YISLKKIEMADGKILCRGSFNYNVIYIADDKNTISNVDGKVDINEVIEKDNVIQDMEY
                     MLFSEVEHMDCTIMNERKIKVGALMNIRGSLFEKQRLDIVKDVAQVEGIQKHRKEICF
                     QDIVGIEKAESSIRDTITINTEEIQSIISLNPCVKVKESRVTDNKVIIGGVLEINPLA
                     CTYEGELVELDRVGIEFTQFVEVPGVSDGMTEEVLLSMSDFNHIFKQNSESNTGLLEI
                     DCMACCKVKVTDEVTREVLQDAYSPQKIIKFDHKPIQLNKTLRRSEETFMVREGIRND
                     NDDIQIKDIVSVCPTMSIENSYIEGNKSIIQGIIKVEILFVPVEGLKLVYKISEEIPF
                     EHDIEMDNLTDTASVFNTACIDKVEVDLNRDQIDLIIKIKRFTEALDKKAENFIIKGE
                     DQGVYDLSKAPSIIVYICKEGDTFWNIAKKYNTTENEIAELNDIKLDEPIKPGKCLIL
                     EKKVVLVD"
     gene            complement(17420..17686)
                     /locus_tag="KOU88_000681"
     CDS             complement(17420..17686)
                     /locus_tag="KOU88_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBK3210594.1"
                     /translation="MATVQTLDKIRVSLERHIGKKILLKANKGRKQIITKEGILEKVY
                     PSVFVIKLDDESNGYPRVSYSYSDLLTSNVKLQVFRDQDKLQIS"
     gene            complement(17834..18694)
                     /gene="yabG"
                     /locus_tag="KOU88_000682"
     CDS             complement(17834..18694)
                     /gene="yabG"
                     /locus_tag="KOU88_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation peptidase YabG"
                     /protein_id="HBK3210595.1"
                     /translation="MKVGDIVARKSHNKDIVFKIVSFGVDENNEKIAILKGIAFRVIA
                     DAYIDDLELVKAPDIKDILIDKNVENLLYKSVRKAKERQKRMTRAVPKLQLNPNTYGM
                     PGKVLQIDGDKEYLKICLDVYAQLGIPAVGVAVSEQNQYKEVRALLEKYNPDILVITG
                     HDAMTIKRGDIEDMSNYRNSSNFVKTVKEARKWQPNLDNLVIFAGACQSNYEKIISAG
                     ANYASSPGRIMIHALDPVFIVEKIACSRIDVVVPIDEVIEQTITGVKGIGGSETRGKF
                     RWAMPKTILH"
     gene            complement(18778..19716)
                     /locus_tag="KOU88_000683"
     CDS             complement(18778..19716)
                     /locus_tag="KOU88_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HBK3210596.1"
                     /translation="MKFIDLHCDTIAKLMENVETSELKSNKYSVDIDRLKKGDSLAQT
                     FALFVDTEEVKHPFDYCMSMANKFHEEMKKNSDEIALATNYEEIMKNQSEGKLTALLS
                     IEEGAVLEGKLENLKKFYDLGVRMMTISWNHVNELSFPHNKVEYREKGLTDFGREVVH
                     KMNELGMLVDVSHISDGGFYEIAKISSKPIIATHSNSRAMMNHSRNLTDDMIKVLANK
                     GGVTGINFFHLFLSDKSESKLEDMVRHIKHIVNVGGIDVVSLGSDFDGIDSKVEIEDI
                     SQMGKLYEPLKKEGFSEDDIEKIYYKNALRVIKEVL"
     gene            complement(19826..19987)
                     /locus_tag="KOU88_000684"
     CDS             complement(19826..19987)
                     /locus_tag="KOU88_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210597.1"
                     /translation="MFILRFADDDDNLSVKDFTSLTDLKKYISENNIDKTWHQIEEVK
                     KVIPNLKEE"
     gene            complement(19997..20494)
                     /locus_tag="KOU88_000685"
     CDS             complement(19997..20494)
                     /locus_tag="KOU88_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEC-C domain-containing protein"
                     /protein_id="HBK3210598.1"
                     /translation="MSLYTEWRNLSDNHESQEAEVKFWEEYLKVEAGIYNEILNNKMD
                     VVEGKVSELAEKFGTTNEFFMGFIDGISESLKEDIVLEEVEADKEVSIKIDWEKLYNN
                     MVTVEAHWLYNLQGWEDILPADQRKEIIKTYKKSKTIVKEAKIGRNDSCPCGSGKKYK
                     KCCGK"
     gene            complement(20609..21319)
                     /locus_tag="KOU88_000686"
     CDS             complement(20609..21319)
                     /locus_tag="KOU88_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0489 family protein"
                     /protein_id="HBK3210599.1"
                     /translation="MENYEYSGFYIEKPVGNNVFSYDKRENKSIYVPKLINGTLNDVR
                     LGNEVVFNEVDENKEIKAKGLENMVEYVLGNKKIYVFDNHNHAFYFWAKSLLKGEFTK
                     GCKLVHVDQHKDTREPENYDVDVNNLKDVFRYTNEVLNVGSFIKPALKYNIFSELIII
                     DSLYGFDLEVESEFVLDIDLDIFSSDMDYIPFELKFYKIKNLIKKAKVITIATSPYFI
                     NQEYAIKVLKELFNYDII"
     gene            complement(21495..22025)
                     /locus_tag="KOU88_000687"
     CDS             complement(21495..22025)
                     /locus_tag="KOU88_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210600.1"
                     /translation="MDIRALPIRITKEEAIEIAKSGKNSLFSKLILKNKYAHEVRLHY
                     IEFKIITLKIHKTKSIFKNRRYSNDINELKILVNGSTGSGSIVQDFPTYEVVKNVDCN
                     IVQYSDKDERRVKAKANKMAMRLTHRFMGGIPEIEIVKIESIFRPYWVVFFGKVELNR
                     RVSYLPIEADGFVIGM"
     gene            complement(22042..22272)
                     /locus_tag="KOU88_000688"
     CDS             complement(22042..22272)
                     /locus_tag="KOU88_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210601.1"
                     /translation="MSKLVSKVKKDLEIKWLGIDGFLVLLYFLITGFIFYGILTRNDI
                     IVGKIIPYGVMAVVIVIFFDYIYRVLKMTRKK"
     gene            complement(22287..23681)
                     /locus_tag="KOU88_000689"
     CDS             complement(22287..23681)
                     /locus_tag="KOU88_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBK3210602.1"
                     /translation="MLTFWENGIIVIFAFILLGIGYYFSRNVKDMESYYLGNRSLPWS
                     LIVGTLVASWYGGVGTVGSVEYAAIYGISAWAVWSIAAHIGRMPLALWVGPRIHIRTN
                     ITVPDLLESFYGKHVAIIGAILMFIYCAQLGEITAMGTIGNVAWKIDKELIGLIMVGV
                     VVVLTVLGGLMGVAITDMVLFFCMVFGLTMVMPGQFEQIGGFQGLTEALKDAPQLMHP
                     TKGMSAMKALMLIVYSFGAYSDPTFYQRFSAADSPKVGRRALLTCFSLWICFDMVLTM
                     TGLIVRATYPEMAPAAGYITLVLDTLPQGIRVIFIIGILGSIISTLDSYYLAAGATLA
                     NDIYGRITKKELSQKQLVKFTRIGVCLAAVMGLSVAFRFENVYDACIFVGSIWMGSAF
                     VPIVGGLLGNGRRTSMGGILGMIVGGVTFGYFKIFPVQSFELEPLVIAIPFSFIAWMI
                     GNRIGENLNTQNNL"
     gene            complement(23807..25060)
                     /locus_tag="KOU88_000690"
     CDS             complement(23807..25060)
                     /locus_tag="KOU88_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3210603.1"
                     /translation="MENKSNFKRFLIIFILAFGTTAMYSLPYMKSSFYDPMQQALSLS
                     HTQIGNLLSLYGLVGMVSYFIGGWFADRFSVRKLITFSLIASGILGFYFSTFPSYSMI
                     LLIFVLWGFTTILTFFSASVKVVRMQGSESEQGRIFGFYEGLSGVSGTLISFIGLYFF
                     GKFAEITVGFKYVVWLYSAASIICGILLFFLVEEKKDSGASDEGLSIKSLLKVVTMPK
                     AWLIGLIIFSTYLVFSSLTYLSPYLSEVYVMPMTLVSALSIIRTYVIKMGASPVAGVI
                     TDKVGSSIRVMFVGFILMTVSTAAYLVIPKSTGFIWIAVINMIILSVILFGFRGIYFA
                     SVSESNISLETTGAVVGFASFIGFSPDAFYYTIAGNWLDKYGQTGYTYIFILSVVCAV
                     IGIFATYALNKINKRENKGLNNKIA"
     gene            complement(25111..26265)
                     /locus_tag="KOU88_000691"
     CDS             complement(25111..26265)
                     /locus_tag="KOU88_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBK3210604.1"
                     /translation="MSNNINQDLETKIIHWGHSADPTTGALATPICQTATFAAKTVEH
                     FEELCMTWGYVYTRECNPTLTELEAKLAMLENAESAISSTSGMGAITSTILALVKSGD
                     HIVSSDGIFSHTKLFMSELLSKFGVEVTFVDAVNPQNVKEAMRPNTKIVYIESPLNPS
                     LDLVDIKTIAEIAHENKSLAIVDSTFGTPIVQRPIDLGADLVIHSLTKFINGHGDTLG
                     GAVAGSKELIDLVRWPSLCCFTGASLPPMSAWMILRGMKTLDMRMKKHCENGLAVAEF
                     LEEEENVELVKYPALKSHPQYELCKTQMNGLGGGVVSFKLKDGINGLTRDQASRRLMN
                     SLELATIATSLGEEHTLVQMNGENLIRIAVGLESSNDIINDFKQAIEKLK"
     gene            complement(26825..27394)
                     /locus_tag="KOU88_000692"
     CDS             complement(26825..27394)
                     /locus_tag="KOU88_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK3210605.1"
                     /translation="MIIIYGYCRVSTKNQTDNNSLYQQQQEILNKYNDAKIIKETYTG
                     TTTNRPKFEKIISSLKKGDLLVATKLDRLARSTSEGIQLIEGLFAKEVSVHILNIGLL
                     ENTSMGKFFLTTLLAVAELERNMIIERTQLGKEFAKKKKDFKDGRPKKYSNQQIQYAL
                     GLLNSKPYREVVKMTGISKSTLIRAKKSI"
     gene            27597..27824
                     /locus_tag="KOU88_000693"
     CDS             27597..27824
                     /locus_tag="KOU88_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK3210606.1"
                     /translation="MNSLLKEAIDELKNIHCGEVFLLKELFKGYEWNRLEMNIRLKLG
                     KLFLYEVVTNPNLNVEVINKNSAYQQMYKKK"
     gene            complement(28043..28786)
                     /locus_tag="KOU88_000694"
     CDS             complement(28043..28786)
                     /locus_tag="KOU88_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBK3210607.1"
                     /translation="MENYQSTNTCTYNILYVQFNEDFERSKYFSYDVKYPVIYNIRNQ
                     STYVNPVILNNINNAVRMTVNNFKNGLQEEEREYNNAASQNSLPKQSYWVSTSYAVTF
                     NKNYVLSMILNLMGFANNYGPKYNTLNNYNIDLTTGKELLLNDIFRDGVDYINIITDY
                     IKSQINENREMYYSNVELVIPEDQAFYLTDNGIIIYFGVDEIAPESFGIPKFELKFSD
                     FGNFINLRFYCISPDIYVQSRGRAKHFMG"
     gene            28954..29826
                     /locus_tag="KOU88_000695"
     CDS             28954..29826
                     /locus_tag="KOU88_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK3210608.1"
                     /translation="MLLLADKWKDYELIDMGNGEKLERWGSYVLRRPDPQVVWPMESE
                     WALWKNPHGHYHRSNKGGGQWEHKKRYPEQWTINYKNLKFHIKPTGFKHTGLFPEQAA
                     NWDWMIEKIKKANRPIKVLNLFAYTGGATVACASAGAEVCHVDAAKGMVNWAKENIEL
                     SGLKNQTVRFIVDDVVKFVEREIRRGKKYDAIIMDPPSYGRGPKGEVWQIEEKLYSFV
                     DLCMGVLSDNPLFFLINSYTTGFSPIVLENVLSTTIGKKTNTGDIYGGELGIPASRDG
                     KILPCGIFGRWEKK"
     gene            29826..30491
                     /locus_tag="KOU88_000696"
     CDS             29826..30491
                     /locus_tag="KOU88_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK3210609.1"
                     /translation="MIKVIYEDNHLLVVEKPVNILSQGDNTNDKDMVNLLKDYIKKKY
                     NKPGNVYIGLIHRLDRPVGGVMVFAKTSKAASRLSEQVRSKTLKKTYLAVVHGKIKSN
                     SDILKDFLYKNKKTNMVTVVKKSHKDAKEAELNYNVLDFKENLSLVQVNLKTGRSHQI
                     RVQFASRKHPLYGDQRYGKEINKIGQQISLWSNKIEICHPTTKEKMEFTCHPPDKYPW
                     NIF"
     gene            30512..31369
                     /locus_tag="KOU88_000697"
     CDS             30512..31369
                     /locus_tag="KOU88_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3210610.1"
                     /translation="MSKKFSIGEMSKLHKISIQTLRYYDQIDLFKPVHVDQESNYRYY
                     SIDQFSQLDIIKYLKYLGMPLKEIKSKLDENNEEILKLLTNKINIVDEKIKELELIKK
                     VLSTKKETMEKGMKVDEVGKIVRKHIPRRSILSIEYEEGLSSEETMELSRRQIANILE
                     DNISVFYGGVSGLVSIDKFLKEDKVIYDNSFVTVERDLFDIKSQKHITEISSGDFICM
                     TYKGPYKENYTAFKKLVDYVEYKRIPIENYIYEIPIIDPLSTNNEEELLTEIQIQVKK
                     REIDLRCLV"
     gene            complement(31525..34071)
                     /locus_tag="KOU88_000698"
     CDS             complement(31525..34071)
                     /locus_tag="KOU88_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBK3210611.1"
                     /translation="MNIFNKVALQGLKKNRTRTLVTIIGVVLSAAMITAVTTFGVSLM
                     NYMTNGAIIKYGDWHVQFLDVDSSFVQEQRVNDEVANTATFENIGYATLEGNRNPDKP
                     YLFIAGFSKEAFDTLPITLISGRLPENSREILVSSKVATDGGVKFAVGDTISLDVGKR
                     MSENEKLGQSDPYTAGSEVFVPQDKKTYTVVGICRKPVFEESSAPGYTLITKEDKQVK
                     TDSLSLFVTLKNPHQIRSYISSTKDHASIFNDNVLRFIGVSDNNLFNMFLYSVGGIVL
                     AIIMLGSIFLIYNSFNMSLNERTHQFGILSSVGATAKQLRNSVLFEGICIGAIGIPIG
                     VAIGIVSIGLVISVIAKNFANILYVNVPLTLTLSIPAIIVAAVVSMVTILISAYIPAR
                     KAANTPVMECIRQTNEVKIESKSVKTSKLTQRVYGLEGVLAMKNFKRNKKRYRSIVLS
                     LVLSIVLFISTSALVADLKQMSNQRSEVTDQDIIFSTQGMKDNEMLKLYDKLKTANGV
                     YEGLYQKLMTYSCVAKVSELTDDYLNYEGSHSMSEMLELPVDMQFLDDRTYLNIIKSL
                     GLPAEEYTGQNAKLIAVSMVTKDNNIIDIFNSSSMNVSLTPETNGKLEIPERQNVNIS
                     FVKVVPPDSPPGIRSSDVKKASFRVLAPYSAKDKFEIPGVSTGIESLSFQSKNPTQSV
                     AEMEQIIESEGVTNEYNLYNMYGMMDENRNYIFIANVFAYTFIIMISLISIANVFNTI
                     STNIKLRRRELAMLRSVGMSEHDFQKMMNFECAFYGMRALFFGLPIAVISSWLIHKVM
                     VTDDIDFVIPWFSIGISIFSVLFIVFITMLYTINKIKKENIIDALRDDMA"
     gene            complement(34071..34757)
                     /locus_tag="KOU88_000699"
     CDS             complement(34071..34757)
                     /locus_tag="KOU88_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210612.1"
                     /translation="MAFLKIEDLCKVYGKNENKVTALDHVSLTIEKGEFTAIIGSSGS
                     GKSTLLHSIAGVDVPTSGKIYLEGQDVYGQSNEKLAIFRRRQVGLIYQFHNLIPTLNV
                     VENITLPILMDKRKVNQERLNDLLELLGLKERKTHLPNQLSGGQQQRVAIGRALMNAP
                     AVMLADEPTGSLDSKNGQEIIQLLKESHSKYHQTLIIVTHDENIALQADRIICISDGK
                     VVRDERKVNR"
     gene            complement(34840..35829)
                     /locus_tag="KOU88_000700"
     CDS             complement(34840..35829)
                     /locus_tag="KOU88_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3210613.1"
                     /translation="MFRNREFRKFAILFLLITILTVALGFAISIMTGILSIVSATTFG
                     IAFFVFTKNRYKSIAQISEQINLVLHNANHLYIAESDEGELSILQSEITKMTLRIREQ
                     NYALKKEKEHLADSLADIAHQLRTPLTSVTLILSLLENTSDEDERKELIRETEELLIR
                     MDWLITSLLKLSRLDAGIVVFQKEQIDVNNLISSALHQLLIPMELHNITLHIDIPKGV
                     RILGDLNWLSEAIQNIFKNCMESVGDNGKIDIICEDNFLFTQLTIHDNGAGFKKEDLP
                     CLFNRFYRGKNSNTAGYGIGLALCKTIIMRQGGTITAQNHPQGGAIFVIRFPK"
     gene            complement(35816..36502)
                     /locus_tag="KOU88_000701"
     CDS             complement(35816..36502)
                     /locus_tag="KOU88_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210614.1"
                     /translation="MKRIFLVEDDKAIAKNLILLLNSEGFIVTHVSTRSEALVEIAKN
                     KFDLALIDISLPDGNGFTICTEIKEKQDIPVIFLTASGDESSVVTGLNMGADDYITKP
                     FRPRELIARIRTALRKSGRFGSTFEICGLYVDTATGVVKKNGNEVFLSALEYRLLLVF
                     ISNPKSIITRVRLLDELWDAAGEFVNDNTLTVYIKRLREKIEDDPSSPQIILTVRGTG
                     YRLGGSYVSK"
     gene            complement(37002..40208)
                     /gene="carB"
                     /locus_tag="KOU88_000702"
     CDS             complement(37002..40208)
                     /gene="carB"
                     /locus_tag="KOU88_000702"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBK3210615.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQALKEEGIEV
                     VLVNSNPATIMTDKEIADKIYIEPLTIEFIEKIIEKEKPDSLLAGMGGQTGLNLAVEL
                     HDAGILDKYNVKVIGTSIESIKKGEDRDLFREVMKEINQPVIVSDIVTNLEAGLEFAN
                     KIGYPVVVRPAYTLGGTGGGIADTEEELREILSHGLQLSPVGQVLLEKSIKGWKEIEY
                     EVMRDGNGNCITVCNMENVDPVGVHTGDSIVVAPSQTLSDEEYQLLRKASIDIINAIE
                     VQGGCNVQIALNPHSLEYAIIEINPRVSRSSALASKATGYPIAKVAAKIALGYTLDEI
                     ENAVTKKTYACFEPTLDYVVVKIPKWPFDKFRHANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHAPSEGRTLEELKARVVVPDDERLFDLAEMIRRGYKVEMISE
                     ITGVDKWFINKFKWIVEQEEKLKVLKIEDLDKEYLHELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIQPVYKMVDTCGGEFEALSPYYYSTYEQYDEVVVSDKRKVVVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMGIETIIVNNNPETVSTDFDTSDKLYFEPLTEEEVLNI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFRDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWTTNEGVEIAKELGYPVLVRPSYVLGGQGMEITYNEEKLIQYLDDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYSTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTAKSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDKLKVYNIAE"
     gene            complement(40401..41450)
                     /gene="carA"
                     /locus_tag="KOU88_000703"
     CDS             complement(40401..41450)
                     /gene="carA"
                     /locus_tag="KOU88_000703"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002845470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBK3210616.1"
                     /translation="MKARLILEDGTVFIGKAFGYLEESVGEVVFNTSMIGYGEVLTDP
                     SYYGQIVTMTYPLVGNYGINLSSAESEKVQVKGFIVREKSDSPSNFRCEIDIDQYLKQ
                     NKVIGLEGIDTRALTKILRNNGTMKGIITLEDSKLEDVKHKLDKFSNTEAVRTVTRKE
                     VEHIKGNGPKVAVMDFGVKRNILRSFIARGCDITIFPATTSPEDVLSINPDLIFLSNG
                     PGDPEDLEDVIENIKALIGKKPIVGICLGHQLLALALGGKTAKLKFGHRGGNHPVKDL
                     EEGKVFITSQNHGYYVSEVPEQMKVTHINLNDNTVEGMRHEKLDVYSVQYHPEACPGP
                     KDNDYIFDKFLELVK"
     gene            complement(41707..44913)
                     /gene="carB"
                     /locus_tag="KOU88_000704"
     CDS             complement(41707..44913)
                     /gene="carB"
                     /locus_tag="KOU88_000704"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBK3210617.1"
                     /translation="MPKLDSIKKTLVLGSGPIIIGQAAEFDYSGTQACQSLKEEGIEV
                     VLINSNPATIMTDKEVADKIYIEPLTIEFIEKIIEKERPDSLLAGMGGQTGLNLAVEL
                     YEKGILDKYGVKIIGTSVESIKKGEDRDIFREVMKEINQPVIVSDIVTDLQAGLDYAL
                     TIGYPVVVRPAYTLGGTGGGIADNEEELREILSHGLQLSPVGQVLIEKSIKGWKEIEY
                     EVIRDSKGNCIVVCNMENIDPVGVHTGDSIVVAPTQTLSNKECAMLKKASLDILNAVE
                     VQGGCNVQFALNPHSFEYAVIEINPRVSRSSALASKATGYPIAKVSSKIALGYTLDEI
                     ENAVTKKTYACFEPTIDYVVAKIPKWPFDKFKKANRKLGTKMMATGEIMSIGSNFEAA
                     ILKGIRSLETGKYSLVHTPSEERSIEELKKRVVVPDDERLFDLAEMIRRGYKVEMIEQ
                     ITGIDKWFINKFKWIVEQEEKLKVMKIEDLTKDYLLELKKKGFSDKGISDLMKISPEK
                     LYELRSLYNIKPAYKMVDTCAGEIDAISPYYYSTYEQYDEVVVSDKKKVIVLGSGPIR
                     IGQGIEFDYCSVHCVKSLRKMDIETIIINNNPETVSTDFDTSDKLYFEPLTEEEVLSI
                     IEKEKPEGVILQFGGQTAIKLAKFLHEKNIPILGTDFDDIDAAEDREKFDDLLERLDI
                     NRPKGKGVWSLNEGIEVANELGYPVLVRPSYVLGGQGMEITYNEEKLSQYLQDAFDRD
                     HKNPVLIDKYLTGREIEVDAICDKEDILIPGIMEHLERAGVHSGDSTTMYPSQNISDE
                     IKEKIVEYTKKIALDLNVLGMVNIQFIEFQNELYIIEVNPRASRTVPYISKVSGVPIV
                     DLATKCMLGAKLKDLGYGTGVYKEPKLVSVKVPVFSMSKLSKVEVSLGPEMKSTGEVL
                     GVGENLEEALYKGFLAAGRHMSDERGVVLATVNNHDKDEFIEIAKDMKELGYTFVATE
                     GTANSLRENGIEADIVNRVEESRPNILDAIRNKQVDIVINTPTKGNDSTRDGFKIRRT
                     AIEFSTEIMTSLDTLKALVEVKKKHLNKDELKVYNIAE"
     gene            complement(44966..46009)
                     /gene="carA"
                     /locus_tag="KOU88_000705"
     CDS             complement(44966..46009)
                     /gene="carA"
                     /locus_tag="KOU88_000705"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBK3210618.1"
                     /translation="MKGKLILEDGTVFEGKAFGYLKEAIGEVVFNTSMAGYGELLTDA
                     TYYGQIVTMTYPLIGNYGINLEDVESNKVQVKGLIVREKSDNPNNFRCEMDIDTYLKQ
                     NKVIGLEGIDTRALTKIIRNNGTKRGIITLENVSLQDVQSKLEEHCNKDSVKNVTRKE
                     IENIKGTGAKVVVIDFGVKNSVLESLKACNCDITIVPAMTTVEEILNINPDLILLSNG
                     PGNPEDINDIVENIKKLIGKKPLTGIGLGHQILALALGGKTSKLVFGHRGGNHPVKCL
                     ETGKVFITSQNHGYNVSEMPENTEVTHINLNDNTIEGMRHKELPIYSVQYIPEYTTKE
                     DLDCIFNKFLALI"
     gene            complement(46035..46751)
                     /gene="pyrF"
                     /locus_tag="KOU88_000706"
     CDS             complement(46035..46751)
                     /gene="pyrF"
                     /locus_tag="KOU88_000706"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBK3210619.1"
                     /translation="MINGKEKLIVAIDTDEFDKAKELIDRLEDSVDIFKVGLEQYVAT
                     KGKTIDYLKEKGKKIFLDLKFHDIPNTMKSAVKAAVRDNVWLMTIHVSDMEGMRQCAL
                     IAREEAERLNIEKPLVVGVTVLTSLSNQDLQDIGCNMTTEELAIKRAKLAKESGIDGV
                     VCSAQEVDKIVEACGTDFITVCPGIRPKSAEVGDQKRVVTPSDAIKKGAHYLVVGRPI
                     TKAENPRESAINIVKEIENA"
     gene            complement(47127..47762)
                     /locus_tag="KOU88_000707"
     CDS             complement(47127..47762)
                     /locus_tag="KOU88_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1847 domain-containing protein"
                     /protein_id="HBK3210620.1"
                     /translation="MYKCGKCNLRGCSNGNMDKLMKICPTREIELQQKAKQLYEEEEN
                     RKIAYNAGLVEAGGYCQYTRLKEIIEFAKKCGYKKIGIAFCIGLKREMQTVQKIFEHH
                     GFEVFSVICKNGAMPKSTIGLEASQTISKCSDEVMCNPIGQALFLNEAKVDLNVILGL
                     CVGHDTLAMKYMEAPITTLVVKDRVTGHNPVAAIYNAESYFEKKLFDKDEE"
     gene            complement(47786..48700)
                     /locus_tag="KOU88_000708"
     CDS             complement(47786..48700)
                     /locus_tag="KOU88_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210621.1"
                     /translation="MELYEAIFYRKSVRNFSSKKIKKPLMEEIKRSCKNLEYLNEDLN
                     IKAHVVDRGHIIHFLMGKECKVKAPHYIVVTSDKGEDYLQNIGFATEGVVLRLTTLGI
                     ATCWLEGNLKREDILEFVDIGNKNFEEDEEDDLDYLAGIKTEEDDENKIENPYIIIAF
                     GYPAKNEELFRTRYARPDRKPVKDMINKINRNRKWKDILELTRRAPSVKNSQPWYFHK
                     DERGLHLFEKRPKKHCEDMNKVSLGVALRHFDIACIKNKIDVSYEKLPIRNKIGKSYF
                     ITVVEHVKPEEETQEENVTLEKEESQDE"
     gene            49300..50529
                     /locus_tag="KOU88_000709"
     CDS             49300..50529
                     /locus_tag="KOU88_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBK3210622.1"
                     /translation="MNLNRNLEKYAELAIKVGVNIQPGQILLIKSPIECADFARNALK
                     EAYKCGAKNVYIEWSDEESTLIKYLYAPDEAFHEFPKWTAEQYVDIAKEGGAFLSVYA
                     QNPDLLKDVDPERVANFQKASGKALKEWRSYTLTDKCKWSIVSVPTKDWAKKVFPNLS
                     EDKAIEKLWDAIFKCSRVDGQDPIKAWEEHNENLKSKMDFLNKNNFKTLKYKSSKTDL
                     TLDLPKGHVWLSGASKDPNGISFNPNIPTEEIFGMPHKFKVNGTVYSTKPLVYGGNII
                     DNFFLTFKDGKIIDFSAEKGLDTLEKLIETDEGSHYLGEVALVPYNSPISNTDIIFYN
                     TLYDENASCHFAIGSAYKTCLEGGNNLKDEELDEHGVNDSLTHVDFMIGSADMDIIGE
                     TYDGKQIQIFKNGNWAF"
     gene            complement(50734..53115)
                     /locus_tag="KOU88_000710"
     CDS             complement(50734..53115)
                     /locus_tag="KOU88_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocysteine S-methyltransferase family protein"
                     /protein_id="HBK3210623.1"
                     /translation="MEIRQYLKNNILIFDGAMGTMLQQKGLKLGENPEVFGLQNPDKL
                     IEIHTAYLEAGSNVILTNTFGCNELKLDSKYTVEEVIDNAVLVARKAIENVDNTKPRY
                     VALDIGPIGEMLEPMGTLSFDKAYEIFKRQVLQGVKSGVDVIVIETMMDLYEAKVAVL
                     AAKENSDLPIFCTMTFDEGGRSFTGCMPECMVATIEGLGVDAIGVNCSLGPKQLLPIV
                     EKIASRATVPVMVQANAGLPNIVDGEAIYDVDAKEFFEGVKKFVEVGATIIGGCCGTN
                     PSFIKEISENINSVTKGCIEKIDKCVVCSPSKFVEVQSPTVVGERLNPTGRKSLQEAL
                     KNENVDYAINLGLEQVNAGAQILGVNVGLPEIDEKKLMPKLIREIQAVVDTPLQVDSS
                     NVEALEQGLRYYNGRTIVNSVNGKEESLESILPIVKKYGSCVVGLTLDEKGIPKKAEE
                     RFEIAKRIVNRAVSYGIKPKDIFIDCLSLTVSAQQEEAIETIKAITMVKTLGVKTILG
                     VSNISFGLPNRKALNASFLTLALGAGLDLAIINPNEYSMMEAINSFKILNNTDKGCIN
                     YINQYSNINNSKKSDSSTKIDKDLPLDILVERGLKDEAKNVTLNLLKEKDENYILDEI
                     LIPALDKVGKRYDSGDIFLPQLIQSAETVKVSLNTIKETLLSKSSNNVSKGKIIVATV
                     KGDIHDIGKNIVKIMLENYGYEVIDLGKDVPIEEVVEVAKKRNIKLVGLSALMTTTVQ
                     SMKDTIQALRDNEINAKVFVGGAVLTEEYAEEMGADYYSKDAKSAVEIAKLNF"
     gene            complement(53087..53812)
                     /locus_tag="KOU88_000711"
     CDS             complement(53087..53812)
                     /locus_tag="KOU88_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Vitamin B12 dependent methionine synthase,
                     activation domain protein"
                     /protein_id="HBK3210624.1"
                     /translation="MENNLIGREDISINQSEVLRYLQYRGQEIDKDLKYTIDECVAIT
                     KNKINPRYLSRIYPIKINKDNVVELEGTNLTLESKDVYELLKECNECVIMAATIGIDI
                     EKEIRRHSYSNLTKGLIIDSCGTTAIEEVCDIVQNNLEKVFLKQDKFITMRYSPGYGD
                     LPIEKNIDILNVLNAQKQIGLTITSNGIMIPRKSVVAIIGISNTRINKSKKEKSCENC
                     KNYRNCTYRKGANSCGNKTISEK"
     gene            complement(53802..54257)
                     /locus_tag="KOU88_000712"
     CDS             complement(53802..54257)
                     /locus_tag="KOU88_000712"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBK3210625.1"
                     /translation="MEKVESFKLDHTKVKAPFVRKCSVLDGVKGDKVTKFDLRFLQPN
                     VESFGTAAMHGLEHLLATYLRDTLDGVIDLSPMGCRTGFYLILWGDVDAKTVKIGLEE
                     ALKKVLESDKMPAATAIECGNYRDLSLFGAKEYAKDVLDKGFSLNIYGE"
     gene            complement(54539..55720)
                     /locus_tag="KOU88_000713"
     CDS             complement(54539..55720)
                     /locus_tag="KOU88_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK3210626.1"
                     /translation="MKNKSLLNHMFRPILDLIISCALTSMLILTSMYIIKSLYVNSDM
                     SVVNQLVYQARDFRSLIGYDLFYPFLFTITSLAIYSMISYKRNKQIVDFIRKTNRKNQ
                     KLEIIKSAVNLMDEGNLEKSIDIEYDLDILKDKEKDDIDELAHKINNIVHQLRNITIE
                     ERQAQQTKTDLITNVSHDLRTPLTSIMGYLGVIEEGKYKDEVQMMYYVDIAYEKSKNL
                     NVLINDLFELTKMQNNTIKLNKIEINLVELLSQVVSQFEIYFKQEFMVSRINFNEEKL
                     IVKADPNKLVRAFENLITNAVKYGKDGHYVDIVTEKKEDMAVVKVINYGEPIPVLDLP
                     NIFDRFYRVEKSRNRNVGGSGLGLAITKNIVNLHDGEITVSSDKYQTVFEVQLPIIQS
                     A"
     gene            complement(55710..56402)
                     /locus_tag="KOU88_000714"
     CDS             complement(55710..56402)
                     /locus_tag="KOU88_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210627.1"
                     /translation="MNNTVLVVDDEKEIRDLIEIYLLNSGYNVIKAEDGKEALDILKK
                     ENIHLMILDIMMPKMDGIEVCRKVRESLNIPILMLSAKSEDMDKIQGIMTGADDYLTK
                     PFNPLELTVRVKSLIRRAYYFSGANNEDKDVIKVGVVIIDKEKHSVTVAGNEIILTSR
                     EFDILYLLANNKGRVYSTEEIFEKVWKEKYYQSNNTVMVHMSRIRDKIEKYTDGEKII
                     HTVWGVGYKIEK"
     gene            complement(56536..57252)
                     /locus_tag="KOU88_000715"
     CDS             complement(56536..57252)
                     /locus_tag="KOU88_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBK3210628.1"
                     /translation="MKKFKLIGAIILVVFISVFISKDRLLKKDKDPIVAAQHDSEQDV
                     EANSQNKNHSNSISNILLVNKTNGISKNYTPENITKVNIPFVEEATEEEKQMAGEPAK
                     AVEDLVKQANSEGIQFLGSSAYRSYDTQLDTYTRRVKSQGREKADAYVAKPGYSEHQT
                     GLCIDLTNPERWFVGSTKEAKWLAENAHKFGFIIRYPEGKEDITGTAYEPWHIRYVGK
                     DAAEEIYSKGLTLEEYLQNK"
     gene            57377..58111
                     /locus_tag="KOU88_000716"
     CDS             57377..58111
                     /locus_tag="KOU88_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBK3210629.1"
                     /translation="MSIQKLLSKARKAIQDFDMIQENDKIAVGLSGGKDSLTLLHILK
                     SYQRFSPQNFELIAITLNTGGVDNSPLDKLCKEINVPFYEFQTDIKEIVFDIRQEKNP
                     CALCANLRRGALNDNAKKLGCNKVALGHHKDDAIETFLMSMFYEGRVNCFSPKTYLDR
                     QDLTVIRPMVYIEEYMTKKISKDSNYPIITNPCPANGHTRREYIKNLIANLNKEMPDF
                     KRNVFGALNNSEKLFIWDKEKIKNFK"
     gene            complement(58396..59247)
                     /locus_tag="KOU88_000717"
     CDS             complement(58396..59247)
                     /locus_tag="KOU88_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK3210630.1"
                     /translation="MNSKIKYFLKFFILIFILIFIYSVAIEPSLLIVKKYNISENGAL
                     IKNDSIESKSESVKVVQISDTQIGSFYSTKNLKKVANKINTLNPDIIVFTGDLIDYSN
                     KNPSVDEITTILSSMNARLGKFSVFGNHDYMYKLPRYYRQIMKNSNFNLLVNENKKIK
                     LKDDKYINILGVDEILNGNPNIKYLESQIDNKSFNLLLAHEPDLVDMLSKDTMNLVLS
                     GHSHGGQIRLPIKGALVTPPYGRKYTKGFYDINGNHLYVSSGLGSTKLPFRFFNIPEI
                     IEFNIII"
     gene            complement(59273..60211)
                     /locus_tag="KOU88_000718"
     CDS             complement(59273..60211)
                     /locus_tag="KOU88_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK3210631.1"
                     /translation="MKSILIMGGSDFIGSALAKRLIKCGYQIDILTNGKKEIDYNGFK
                     EHLICDRKVRKDMENIITGRKYDYIYDMTAYTKEDVSNLIDFISMDNLKKYIVLSAGA
                     VYKDSGRNIKEENEKGENENWGKYGLNKKEAEDFIINSPIPYIIIRPTYIYGENNNLY
                     REYYFFEKIEKNEKIPVPKGKQVSNQFIYIGDLVKVLESIMKNPHVREAYNVTNPQLI
                     SWDDLIYTCGEIIGKEPIIKYVDMEKVEFRERTYFPFRNIDFNLDINKLIEHGLYIPN
                     VLLKEGLTATYKWFSANKPKMHDRKMNKVESVMQIV"
     gene            complement(60314..60964)
                     /locus_tag="KOU88_000719"
     CDS             complement(60314..60964)
                     /locus_tag="KOU88_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK3210632.1"
                     /translation="MKKNYEIVLFDLDGTLTDPKEGITKSIQYSLNSFGIKEDLENLD
                     QFIGPPLHDTFKEYYKFEDKKAKEAVEKYREYFADKGIFENKIYENMKEILEMLYKNG
                     KILLVATSKPTVFAETILRYFDIDRYFKYIAGSNLDGTRVNKNEVIQYVLDLCNVKDK
                     DKVIMVGDRKYDIIGAKKIGIDSIGVLYGYGSFEEISESEPTYIVENVESIKDILL"
     gene            complement(61113..61301)
                     /locus_tag="KOU88_000720"
     CDS             complement(61113..61301)
                     /locus_tag="KOU88_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBK3210633.1"
                     /translation="MKAFVDKDVCVACGACIGTCPDVFSMSDEGHSVAIEGEIPADLQ
                     DLCKEAEEGCPVSAITVK"
     gene            complement(61408..62592)
                     /locus_tag="KOU88_000721"
     CDS             complement(61408..62592)
                     /locus_tag="KOU88_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBK3210634.1"
                     /translation="MKNLLIRNGTIISPTDGIKFEKRDILVLHGKIYAIGLNLKEKIR
                     KEKLLTNKEFEIINADNMYISPGFIDVHTHCYKRKLPTGMDSDSIGIEKGSTVIFDAG
                     TAGPSNYYDFKKKYMDECKTEVYSFLNVTNEGLNILNESTYLDVINFDKVESIVEKNI
                     EKIKGIKVKASKFQSNESGIDIIKKSKQVAKKLNLPLVVYIGEYPSYIDEVMNILGKG
                     DVVTPVYGNSTNGILKESGTLRKSVINAKNRGVLFDVCHGVDQFDFKVFKKAIKQGLE
                     PDLISTDMHIKNMKDVNYSLLNVINKIMELGISLEKCIEKVTEYPTKIFDLHGNKGRI
                     KIGGEGDFTIFTMEECNDIIKDYNNNELVLNKKLRLQYTVKSWMKSSEVYRHGYENTI
                     IN"
     gene            complement(62734..63651)
                     /locus_tag="KOU88_000722"
     CDS             complement(62734..63651)
                     /locus_tag="KOU88_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufD family Fe-S cluster assembly protein"
                     /protein_id="HBK3210635.1"
                     /translation="MNKIDLNLLEKVAELRGTPLGAYNIRKNGQGVERHSTENVTIIP
                     KTDKPGIDIIVKPNTKGENVHIPVIVTEAGVQDMVYNDFEIGENADVVIIAGCGIHNC
                     GCDDSEHNGIHRFFLRKGARLKYVEKHYGEGDGEGKRILNPVTIVNMDEDSYCEMETI
                     QIKGVDSTKREMDANLGKGAKIVVFEKLLTHGNQVAESNMKVILEGENSSAQVVSRTV
                     GQDNSKQKFNPCVIGDSLCSAHVQCDSIIMGNSQISAIPEIAANHPDALLVHEAAIGK
                     IAGDQILKMMTLGLTKEEAEQQILNCFLK"
     gene            complement(63673..64401)
                     /locus_tag="KOU88_000723"
     CDS             complement(63673..64401)
                     /locus_tag="KOU88_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3210636.1"
                     /translation="MLEIKNLSFNVESNNEELGIINDVSLSFERGKLIVITGPNGGGK
                     STIAKLIMGIEKATSGQIILDGEDITNLSITERAKKGIGYAFQQPPRIKGMTVENLLT
                     LAHGKPLSTDVCCQYLTDVGLCSKDYLNREVDNSLSGGEMKRIEIATLFARDLKVSIF
                     DEPEAGIDLWSFGKLNESFKKIHEESNQTIIIISHQERILELADEIIVLQDGSVKSHG
                     TKEAILPEIMCQVNSSCELMKDMN"
     gene            complement(64597..64797)
                     /locus_tag="KOU88_000724"
     CDS             complement(64597..64797)
                     /locus_tag="KOU88_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210637.1"
                     /translation="MFKKMAVLKDIATKIGRKKAYELLEMVEGNDAFVAEVKIKKNGI
                     ESKKEEIMLKDNQKIILEYIEG"
     gene            complement(64922..65302)
                     /locus_tag="KOU88_000725"
     CDS             complement(64922..65302)
                     /locus_tag="KOU88_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK3210638.1"
                     /translation="MINKIGKITLYVNNQEDAKLFWTEKLNFVVTYEKEMGPNMKWVE
                     VAPSKNEFTTFVLYDKNLMMKQNKEINVSHPSIILSTRDINGTYEQMANNEVEVGELM
                     EMPYGRMFSFKDQDGNDYLVREDK"
     gene            complement(65575..66933)
                     /locus_tag="KOU88_000726"
     CDS             complement(65575..66933)
                     /locus_tag="KOU88_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3210639.1"
                     /translation="MFIRKNVIKLAIPIMIEQTFVMLLGVFNTMMAGHIGEEAVSAVG
                     MVDSINNIFISVFAALSVGATVVVAQQIGKKDSEKVNETIKQALVSGVILSFTITILM
                     WVFRTGVINLFYGSAEELVKSNAKLYIEFTLFTYPFIATQQIANGILRGCGDVKKPMY
                     VTMFMNIVNVTLGYILIYGIDLNPLGINLQTPSYGITGAAISIAIARIIGCIVIIRAL
                     FKGNEFISMGKIFPFKIDVETQKSIFNIGIPAGVEQLLFNAGKLIVQVFIVTMGTSAI
                     ASNAIGMSIASIINVIGNALALSATTLVGQYIGRGDIKGAKSTLLYLTKFATICLFIV
                     GAIFIPIAPWISSMYTQNASVIDISTQLIRSDCLAMVIWPISFVLSAGLKGAGDTRYT
                     MMTAVIGMWIFRIFTGYVLGVVLEFGVLGIWIGMYTDWLVRGTLYCLRLRGTKWLKHK
                     VA"
     gene            67381..67833
                     /locus_tag="KOU88_000727"
     CDS             67381..67833
                     /locus_tag="KOU88_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staygreen family protein"
                     /protein_id="HBK3210640.1"
                     /translation="MVNLNANNLNVNMVYPISSTAPIRFRRYTVSYLENMENIYLTIA
                     TYFDTLGLGTMNIDKVYGQWAWFTDNIYDLNLFVFVGNYPYQIAKNRYDTFVDILPVA
                     ITSIVNGDRVFLISNPCLLNSKITVRFISSHPTLNRTVDYGNIRDFIF"
     gene            complement(67990..68607)
                     /locus_tag="KOU88_000728"
     CDS             complement(67990..68607)
                     /locus_tag="KOU88_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBK3210641.1"
                     /translation="MEIFAIGHSNYPYDKLINMIKKYDINCVVDIRETPYSKYNIQYN
                     KEAFNESLRNSGFLYIYMGKEFGAKRTNKDVYTQEGYADFEKVAKEDIFLNGIERLKK
                     GCQMGYRIVLLGAMQEPIRCHRSILVGKVLNKEGFDVKYIMHEGNLAYQEDIEESLLD
                     KYFSDRKQLSIDNLLGSALTREEMIQEGYKLANKEIGYRTEKLGK"
     gene            complement(69030..69842)
                     /locus_tag="KOU88_000729"
     CDS             complement(69030..69842)
                     /locus_tag="KOU88_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3210642.1"
                     /translation="MFSIGMFSKINKITTKTLRYYEDIGLLKPEYVDEFTKYRYYTTE
                     QLPKLHQIITLKQMGLSLAEIKKAVENPEEVENILMNKEKEMLDVIKSEEYKIIKLRN
                     YLMNLKGEVNMNDVIIKSLPKVKVASMRKVLKGYDELFNLFPNVMAEEMMKTGCTCAV
                     PDYCFNIYHDGEYRETDMDVEMCQAINDLKEDTDILKFKELDAVENAVCILHNGPYST
                     LGKTYADAFKWIEDNKYKVVGNPRESYIDGIWNKESEEDWLTEVQIPVKRML"
     gene            complement(69918..71336)
                     /locus_tag="KOU88_000730"
     CDS             complement(69918..71336)
                     /locus_tag="KOU88_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBK3210643.1"
                     /translation="MTELMIISGLVLLICITSSKVLYKFGVPILLIFILLGMLFGSDG
                     MVGIYFDNYELTKQLCSIGLIFIMFFGGFGTNWNMAKPVAIPSILMSSLGVIITAGVT
                     GMFCHMVIGTSLLEGLLIGAIAASTDAASVFAVLRSQKLNLKGSLASLLEVESGSNDP
                     IAYMLTLILLTLMNNSGVELIAPMVIKQIAFGLAIGFILAKLSVYILRHSNFEIEGFY
                     TIFITAIAILSYAFSEYLGGNGYLSVYISGIIIGNSRIPLKKSLVHFFDGISWIMQIM
                     LFFMLGLLSFPSKLPNVFGIAMAISIFMIVIARPLATFIVLAKFKFSNKEKLFISWVG
                     LRGAASVVFAIYAVTQGVAIENDIFHIIFFIALLSVGIQGSLIPTVARKLDLVDDNTP
                     VLKTFNDYDGEISSKLIEVNVDEGNKWANKSIIDSNIPDDILIVMIKRKEQVLIPKGS
                     TIIKTGDILVLSGDRIEELIQL"
     gene            complement(71820..72737)
                     /locus_tag="KOU88_000731"
     CDS             complement(71820..72737)
                     /locus_tag="KOU88_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HBK3210644.1"
                     /translation="MVNMNIIEIRSDKIYKKIMDAPINKKEDIYRYELMKPFEFKWKC
                     MNVPIVARQKGGYDVIIASEMLGVLSPKDIDEKQKKNINVLSADKIWGTCKETIENSI
                     NAFIKEGYDLNIKDYKYSILLANPNSPYTILSDGYWGDGGIPGYIFLSLVPNEYTINR
                     LPVLIAHECNHNIRFQFIEWNNNITLEEMMINEGLAENFATWMFGEEMLGPWVSRTDI
                     ETLNTYIKPIIKSALKETGFQNITSYLYGDDIAKMQGYFPVGLPYCAGYACGYYMIKY
                     YLEKTNKSIIEATLLPYSEIIEAVKEFWE"
     gene            72999..73376
                     /locus_tag="KOU88_000732"
     CDS             72999..73376
                     /locus_tag="KOU88_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK3210645.1"
                     /translation="MLTPYLIFNGTCEKAFNFYAEAFGGGKTIFARLDSNPNNPIMHA
                     SVTFTKYEGCIMGADTDKPVVISGMAICVVLPSREAIEEISVKLAEGGTLVQEFLPHP
                     PPHQNDGAAEVLDRYGYTWYLST"
     gene            complement(73532..73981)
                     /locus_tag="KOU88_000733"
     CDS             complement(73532..73981)
                     /locus_tag="KOU88_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3210646.1"
                     /translation="MKSGIILEMKQINSTEYDEMLQVWESSVRATHDFLTEKDIESLI
                     PLVEIGLKEVENIVCIKDNDIIKGFIGIDKDKIEMLFIEDKYRGNGIGKKLIKYAIDK
                     YNVKYVDVNEQNKKAVGFYIHLGFKVFDRSEIDGQGNPFPILHMKLI"
     gene            complement(74145..74549)
                     /locus_tag="KOU88_000734"
     CDS             complement(74145..74549)
                     /locus_tag="KOU88_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmaF family protein"
                     /protein_id="HBK3210647.1"
                     /translation="MSYQNYKCERDYVYDDYKYNKCNKCYNDYEEMTHVHEYSESVKL
                     AEECEDRHNHRAAGVTGEVIPINGGTNHVHKINDNVDFLDHFHKICVTTGPAIRIPGT
                     DKHIHLICGETTVNDGHCHKFLFTTQIEAPLV"
     gene            complement(74662..75528)
                     /locus_tag="KOU88_000735"
     CDS             complement(74662..75528)
                     /locus_tag="KOU88_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBK3210648.1"
                     /translation="MIDIHKNIYDNKLFEELKIDCKKCFGLCCVALYFSASDGFPINK
                     ESGKPCINLQPDFKCSVHNSLIKRGFKGCTAYDCFGSGQKVAQVTYKGIDWMQSPELT
                     NQMSEVFLIMRQLHEMLWYLKEASVLNISDTIKSKIDLIIEETEKITNMGPEQIINLD
                     IISHRTKVNLLLSQASESMMGKVKSFIKTSTLKNMKKLSKNIDLIGADLRKINLIGAD
                     LRGRFLIAANLRNTDLSGANLIGADLRDCDIRGANLENSIFLTQLQVNTAKGDSSTKL
                     PASLIRPKYWEK"
     gene            complement(76098..76442)
                     /locus_tag="KOU88_000736"
     CDS             complement(76098..76442)
                     /locus_tag="KOU88_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBK3210649.1"
                     /translation="MENLPNCPKCNSEYTYEDGTLLVCPECSHEWALGLGAEEDSNII
                     KDVNGNVLNDGDSVTVIRDLKVKGSSSSIKIGTKVKNIRLIHDSSDGHDIECKIDGFG
                     AMKLKSSVVKKA"
     gene            complement(76631..77248)
                     /locus_tag="KOU88_000737"
     CDS             complement(76631..77248)
                     /locus_tag="KOU88_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210650.1"
                     /translation="MISLINISKKFKDKSIIDKFNLEISKGEFVAITGNSGSGKTTLL
                     NIMGLLEKPNSGDIIINNIKNPNSKQIRILQRDFYGYLFQNYALIENENVENNLKIAL
                     KYQKNINHNEKINYALESVGLRKYNKKKIYELSGGEQQRVALARVILKECEVIFADEP
                     TGNLDKKNRDIVFDILKSLNKNGKTIVFVTHDLDLSEQADRVIKL"
     gene            complement(77253..79415)
                     /locus_tag="KOU88_000738"
     CDS             complement(77253..79415)
                     /locus_tag="KOU88_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBK3210651.1"
                     /translation="MKKIIYVLFTIELLIVSLLGLNIVKDNEINNILYNDTTSISVMF
                     KDYKKLNKNYSKWIKDIADENNVAISKYVFNNNEKLSIYTTDTSLNNNIKLKSGKFPN
                     TNSNEFISNINTNNSNQVGKFSTMSKDISILIRDFGKISEVGESGILYISTQNEDTIN
                     KILRELNVDRSIFVARLHDRYVNSNLYLNPSIIRDLILIILCFLATIIHYSISVSREA
                     SILRLNGYSKLDIIARVIKNILRIMILSSVTALLIYIIYILKLNIGVRACLYFAMFSI
                     ICILINILISILIVGFNSRSSKYVLSLNGKKSYGFVNIMHFTLKIVFVSFLILSINNC
                     ILNYNMLQTQLGNLSEWDKAKNVYNLTLKDTGEQSLGKEEVIKNAKIKGFYKNLVEEK
                     DAFLIDSTNFEKLEDGSYMYEINSKGKNPEVSQYGKNIKINKNYLKVNPIYSNGKEIF
                     NLIDYDDKTINLLVPKKLQVHENEIKKEFRELFYFEKIEVENMYNKELNRELNKTKKS
                     DLNVNIIYVDNNQSYFTYNSLVMDDNRNLIDDPIAIVDIDNIDDSFYLSYISRCVYFN
                     SKKLDALADISSIIEAQGVEAHIQSLHAVYNEYGLEINKLEKYLNSEIFTIIIIAISN
                     LMITYNIVASYYERNKYKLYIKKIFGYSTTARSMLLIVSLILTNIIPIGIISTRVDLS
                     NNIILFGLLILVIEVIVSIVLDKIISNSSFNKIIKGEH"
     gene            complement(79757..82264)
                     /locus_tag="KOU88_000739"
     CDS             complement(79757..82264)
                     /locus_tag="KOU88_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBK3210652.1"
                     /translation="MKEDIRLHRMCKKEQATKNEVISEDILKSMSIGVSKHFLDDSFT
                     IIWGNTSFYQLLGYTEEEFLVKFSSLKDYYEQNLYHFESMKNHFLEAYHHGEKSIEYQ
                     ICISANNGDPVWVIMTGILIESQDNEKSMVYILYSKINELKIKQEELSDMEKESTENF
                     KWMMSEYAGNVYISDMDTYELLYLNKHSCNTLQASANELIGRKCYEVIQGRTSPCPFC
                     TNSYLKKDDIYEWEFYNKKLKRTFIIKDRMLNWQGRRVRIELSYDMYSAEYKLAKKDQ
                     ERESILKTIPAGMVRLDARDYLTILWCNDIFLNMIEYTKEQFAEELNNQCGYLFSEDY
                     KRSKKLAQDLKESGDNVVFEAKIYTRSREERIWTVTLCYISGEDSWDGIPSFYSIGID
                     ITKERKQIEKLQHISEKDALTGIYNRAETERQIKKYFEKNLNVMGALFMIDTDNFKQI
                     NDTEGHMIGDIVLTEMASGMKKIMRDSDVVGRIGGDEFTIFMKNISSVKDAEKKAEEL
                     LYMFRHLFQKEKSFLKVTCSIGIAIYPKDGTTFKEIYARADKALYQAKNMGKNNYVIY
                     NQDYFKELEEFDCSSLGTVIDSEKQYAEYPDNLTRYIFRMLYQTDDIDQAINMILEVV
                     GKQFDVSRVYIFENTEDGRYTSNTYEWCNEGISSQMAYLQNSNYQDYEDYEKLFEDEL
                     VFYCRDIHTLSPKLEELFSSQGIHSTLQCAYKEDRVFSGFVGFDECTGLRLWSQEEIS
                     TLSLISQIISMFLQRKKNNKLNQQIQQYQNILDNIDQCICVINKENNFLLYVNKKFKN
                     TYSKFQIGQPYYLDSIDIHKISIIWNKKEAYLCTSTI"
     gene            complement(82741..83373)
                     /locus_tag="KOU88_000740"
     CDS             complement(82741..83373)
                     /locus_tag="KOU88_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketohydroxyglutarate aldolase"
                     /protein_id="HBK3210653.1"
                     /translation="MKKMNITKRMSECGALAIVREENLNRACEIAEGCIKGGITVIEM
                     SYTLNNAGEIIQGLNKKYGEILCVGAGTVLDSETARHAILHGAQFIIAPNYNEGVAKI
                     CNRYQIPYAPGCTSLTEAVDALSLGATFIKAFPISDFYGPKLVKVFKTPIPDMPVLAS
                     GGLNIENLHIWLENGVDVCGFGGLLTKGSVEDIAKNAKKIREIIKNVRKI"
     gene            complement(83479..84384)
                     /gene="dapA"
                     /locus_tag="KOU88_000741"
     CDS             complement(83479..84384)
                     /gene="dapA"
                     /locus_tag="KOU88_000741"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBK3210654.1"
                     /translation="MKYKGIICAMITPFDENQNINSQATCQLIDYLIEKGIYGLFILG
                     TNGECHVLTDDEKVEFAKIVINHTNNRVPVFVGTGGNSTREVVDLSKRMEAIGASALS
                     IITPYFVTPTQQELILHYKTIANSVNLPIIMYNMPGKTGINIEPESVRELSKIKNIVG
                     IKDSSGKLDNMKAYIEATKNENFSVFSGSDSLILDSLKAGSQGAVAATTNFLTEIGIS
                     IYENFMKGDLEEAQKSQSSIEELRRILKLGTIPSVMKKTIVLNGINVGTARLPVTEPT
                     GEVLEEIKRVVENYRTILNKSSENR"
     gene            complement(84389..84988)
                     /locus_tag="KOU88_000742"
     CDS             complement(84389..84988)
                     /locus_tag="KOU88_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK3210655.1"
                     /translation="MENTLSEFLDNISNELSEFIASIDETSINKACELILEAEKNHGR
                     VHVTGIGKPGHVSGYISSLLSSTGTSAYILHGTEAVHGSSGQVVEGDVVIAISNSGET
                     QELKATLKTLKVNGAKIIGVSGNESSFLKNISDIFLFAGVKQEGDCLNKAPRASILAE
                     TIILQSLSVVLQYAKGLNTQEYLKWHPAGSLGKSIREGI"
     gene            complement(85046..86317)
                     /locus_tag="KOU88_000743"
     CDS             complement(85046..86317)
                     /locus_tag="KOU88_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HBK3210656.1"
                     /translation="MEFIISLLSTPAVLLGVVACIGLILQKKSAVEVFTGSSKTLIGF
                     LIFGIGASAMTGALQNFNKLFQHGFGITGVIASPEAATALAQGTYGFAVSCTLILGFI
                     LNLVFARITKFKNIFFTTGHSLFFSCVLVLIMKAHGFDNTITILIGGTILGFMSAALP
                     QFCQPFMRELTGGDEQAIGHFNMIGYCLSGYIGRLFSKHKDDTTETIEFPKWLSIFRD
                     FLMGLSIVMLILFYIATLKAGQAFTQEIAGSTHWLVFPLIEAFTFVAGMSILMSGVRM
                     FLAEITAAFVIISEKYIPGSRPALDVPTVFPYAPNAVIIGFISAYASGLLAIAIMASF
                     PSIFPVVIIPAAHICFFSGGTAAIFGNTSGGWRGAIAGSFVVGLLLAFLPVILYPVYG
                     TLGIEGATFPNIDYNVVGSILHNILQFIKPI"
     gene            complement(86344..86631)
                     /locus_tag="KOU88_000744"
     CDS             complement(86344..86631)
                     /locus_tag="KOU88_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210657.1"
                     /translation="MYKILIACRAGVGSSLMLKIKTQQIIKENNFPIEVEHGSLDSLN
                     GFNGDAVETLIDVAEELKNKNLKFDIIGIHNIVDRNEIKTALEKFLASKEG"
     gene            complement(86646..88733)
                     /locus_tag="KOU88_000745"
     CDS             complement(86646..88733)
                     /locus_tag="KOU88_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3210658.1"
                     /translation="MVVDKEIVSILQILLNSTLITTNGLQEESNSSKRQITYRINKIN
                     DMLKVKNVPLICLRADKDIIVRKETKKAIKEILEKNYSKNTYYFSKTERLLYMYLMLF
                     INMDDISINHFINSIKVSRSTVNLDFKDLIPELEKKNIKVKNNRINGYYIVGNEMEIR
                     RVLIKNIIETLSNEKSSRVFDIFIKEYNLDSFEEAKKIILKLIKKYEITFVEDRLVEF
                     IYIFIFLKARMYSTRIVTQENVDIPNISVMSSMKEYKFAKELLEVYGSEDKIKPHNIM
                     YISAWILGISVGNYEEDTEDKDVISKIVNKMMTKFGYLSGVYYISQEKIFKQLYSHFR
                     PAYYRLLFKLPIYNPICEKVKEEYKLVYRIVSNAMKEFCGLFGEEIQEEELAYLTMHF
                     ATLFSNKKEFDGFRKRIALIVCSNGVGSSAILHAELTNLFPDLHFIPMSESVGLENIS
                     EPVDIVFTTNYNAEGLKTDVPVIKVSPVMTTKEKYKITREVYIQLGDIFLRQPKIDEV
                     MDIIKKYANVTSESILSSELLAYFTQIENFTSKEGEGPMLSEITNETLVKIKVKAKNW
                     EEAIRQSASVLVENNKVTEGYVDAMINSAKASGPYIVITKHVALPHARPEAGSKEIAI
                     GIATLDSPIEFGNNENDPVKYVFCLSAIDNNSHLRAMSELVELLEEDEFFKVLDSAKE
                     AKEIIDFIKTHEL"
     gene            complement(89148..89669)
                     /locus_tag="KOU88_000746"
     CDS             complement(89148..89669)
                     /locus_tag="KOU88_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK3210659.1"
                     /translation="MVLLIVDAQKLITNERLYKFNEFVVNVENLIDTARKNNIEVIYV
                     RHDDGVENELTKGKNGFEIYEKFKPCNGEKIFDKKVNSAFKETGLLEYLTNNGEKDII
                     IAGLQTDYCIDATIKCGFEHGFNIIVPAYSNTTVDNFFMSAEQSYKYYNEFIWNERYA
                     KCISLEETLRKMK"
     gene            complement(89731..90537)
                     /locus_tag="KOU88_000747"
     CDS             complement(89731..90537)
                     /locus_tag="KOU88_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK3210660.1"
                     /translation="MRTEKSLKRPIASFIILTNIIFLPLFLLVVVTIMLKLPTVISDI
                     ALCISAWSSTFAFMILFKKIYPGKKFLVHVKDRFRNKLKFSTVSIIISIQVLIAVVVI
                     FILASKNHGIMPNFTVSSWGAFIYLFLKNLFAGSLGEELGWRGFVQNHLQKRHSPLKA
                     SIIVGFWWGMWHLPIWFTTGFKGLDLIKYIIFFMIAIISISIIMTTFYNLNKTLIIPI
                     VIHQLFNFLIGIINGDLIELINYYAMLYLIFAIALIVINPGNVLYKNIRE"
     gene            complement(90641..91435)
                     /locus_tag="KOU88_000748"
     CDS             complement(90641..91435)
                     /locus_tag="KOU88_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3210661.1"
                     /translation="MYTIGQVSKFLGISRDTLKFYEDKGLVNPKKNDENGYRIYNQVD
                     IYDIATINFYREIDIEIKKIQEIRKSKSINNLELLLEEKEQIILKEIEYKKLLLKKVQ
                     LVKEDCDKIKTYFGKYTIKEMKPLEVKGKIKHVTNYEEYEALKENTNNLKKAVTLTDL
                     RRVINFNEEGIIEEKFIIVREVDDYNKIIEGEVLSHPNCIYTIIEDGRWSTGGENIDN
                     KVEDRLREIAIENECELLGIVYVNILLTTYEEGIERIFLEIYAPIK"
     gene            complement(91969..92823)
                     /locus_tag="KOU88_000749"
     CDS             complement(91969..92823)
                     /locus_tag="KOU88_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase"
                     /protein_id="HBK3210662.1"
                     /translation="MAMGFEFKIMRSLIYVGLAKEEYRPKLMDWLYRHHIPDSISTFG
                     PYCTKYAFYQAYPTPNEGERFGARKMQLTEHYWLVDEHMPEMANRIMTEYMPMDVLRW
                     QGCIPDVENKRVHENAESGDAGRAVGGDNGCPPFIFAFVPINWEEDFRGKGRTVQDGP
                     NYRWQFMIKYPDGISKEEGEKWFYDEVVPYFTNCCYVNRFVSSKIMINYGATAFDRVS
                     ELWFEGEEEWYKAVVEETKSFIKKPEWAQEEEFPYLKPQFNIASVFLGDIATMDAYSQ
                     YRGYIPMR"
     gene            complement(92855..93367)
                     /locus_tag="KOU88_000750"
     CDS             complement(92855..93367)
                     /locus_tag="KOU88_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBK3210663.1"
                     /translation="MDRKKKEILTLSMGIALLPPLWAVLAPYIGIKTGAVALICAGLY
                     VTNGNKQKDGLKIMFGFWCGDLWAVLAILIMGYMNFNQNLELFLTLSILGFFAVVIAS
                     LFEKIIFLPSWLCGWAIGLTIMTGENIINLQDICIQIAVAMAVGVWYVGAGVDLFTIY
                     ILSKDRKKGN"
     gene            complement(93360..93584)
                     /locus_tag="KOU88_000751"
     CDS             complement(93360..93584)
                     /locus_tag="KOU88_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210664.1"
                     /translation="MNEKSSFKQIEIILAVIFLVLTYYKVRLTPAFIVIFIPLYLSYF
                     AVSMIVNQIAIKLLEIRQAREATNYNIGNG"
     gene            complement(93644..94597)
                     /locus_tag="KOU88_000752"
     CDS             complement(93644..94597)
                     /locus_tag="KOU88_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBK3210665.1"
                     /translation="MKILGISFGTKNGNNDTMCKVALKGAKEAGAEVEFIQMSSINIK
                     HCTGCCACVKTLLSGKGSMCVLKDDFEWLLDKMKDADGIVVSDPIFEEGASGLFHTIM
                     DRFGPRADRGNNIIGTKVAEAIGGKIPDSRMLNDKVISFMGIGGSDWGTRVQCEHAML
                     ALIPMWKVIDNAWFPWAKELVMDDTRLVQVHQIGLNIVEAAKDFEKASYQGEEGVCPH
                     CHNRLFYLEPGTKKAICALCGIVGELDTISGKTIFSFPEEQLGHAHDTLPGKFIHGDD
                     IKKMEGHYAEVRKTQEFKERKTSYNFIEPLTKEKQAGVSLG"
     gene            complement(94625..96013)
                     /locus_tag="KOU88_000753"
     CDS             complement(94625..96013)
                     /locus_tag="KOU88_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210666.1"
                     /translation="MEDKFYAKGNGNNGYIKNLEVCSFNNLDGTCGMFQMALYKRDEK
                     YYLYGCCFGGNKKNGVMISDITDPYNPQFIKHFQMLDPKEYPTTTTPKIQIADDLMIV
                     AMSCGSGPGALVDQAKLANIKCEAGIRIYSLKEDPLNPKFLGYWDCGLKHVMGVHRFM
                     YNGGRYVHLSSDCVGFEGLIYRVIDIINPTNPVEIGKWWRPDQYANGYPNRTFDAGAP
                     HCPEFMDKGWLHGPPFVRDGKAYCGYGGAGLVVLDVEDLTRPRCLGELPFMPAFSSRL
                     AGARTHTALPLPGRDLVVVQNEGERFQFFKPDNITDVQAMNNIHMVDVSDPTKPTLIA
                     QFPYPEVPKDFPYPNFNVAGLGKPGPFGPHNLHEPMDNKPWLEQRGDRVYCCYFHAGL
                     RVYDVSDPYYIKELAYFIPPNPNKTPEESYFPGFPGPRLAVTEDLIVDDRGYIIIDAL
                     DDGFYILKMKED"
     gene            96286..97167
                     /locus_tag="KOU88_000754"
     CDS             96286..97167
                     /locus_tag="KOU88_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3210667.1"
                     /translation="MNTKQLEYFISVAENLSFTKTAEKFYISQTAVTQQIKALEEQIN
                     VTLFTRSKRHVELTPAGKVFLSEARTIIKNINDAIAKTQQFAHGFFGTLSIGTLIGYE
                     KNKLQQYLKEFSNTYPNISMDICTNEITELLNLVKNNSMDLAFVINPENQPLKDFEYK
                     TVERYSLVALLPPGHPLYNEDSIDLIELQHDKFIFVKETGDEYGQKSMIQNRYREAGF
                     VPNVVQRSNNLNTIESLVSSNMGISILPSFCVTDTMIERDIAIVPIKEVENRIEVVVV
                     WNKKNTNPALEKFISII"
     gene            complement(97355..98347)
                     /locus_tag="KOU88_000755"
     CDS             complement(97355..98347)
                     /locus_tag="KOU88_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBK3210668.1"
                     /translation="MNILAFGEIMMRLSVPDYKFLTQTNELNYITTGTGLNILSGLKN
                     FGYNTYMLTKLPNNNVGKASSANIRKLGVKDDFITYGGNHIGVYFLENGYGERPSEVT
                     YLNRLNSSFCESKLQDYDIDKCLEEMDIVHICGIAMQLTDSVKEIALELARKSYEKGI
                     KVFFDFNFRQSLNPERTYDDLVNDYKKILPYCHGLFASYRDINKILNIDSLNIKSSSE
                     LIKKEYDIDIVAGTMRRFDDMNNRFIKGYISNDDGYFESREYKLEIYDRVGAGDGYVA
                     GIIYSYLENMKSEDIVEFGVASSVLAHTTYGDNSLVSTGHVLRLMNNEKIDILR"
     gene            complement(98352..99092)
                     /locus_tag="KOU88_000756"
     CDS             complement(98352..99092)
                     /locus_tag="KOU88_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KDGP aldolase family protein"
                     /protein_id="HBK3210669.1"
                     /translation="MNCIPQYYKNRVCLNVLAGSIKNAKEVYDACDGHVLIGILSKNY
                     STVEAAIEDMKKYSKEIDNAISVGLGAGDPNQSNMVSQISKELQPQHINQVFTGVATS
                     RALLGQNDSIINGLVSPTGKPGFVKISTGPLSSKEKDGIVPIETAIAMMKDMGGSSIK
                     FFPMGGLKTKDEYIEVAKACAKHNFYLEPTGGIDLDNFKEIVQIALDAGVEKVIPHVY
                     TSIIDKETGETKVEDIGVLYKIMKELLG"
     gene            complement(99157..100266)
                     /locus_tag="KOU88_000757"
     CDS             complement(99157..100266)
                     /locus_tag="KOU88_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgaE family pyridoxal phosphate-dependent
                     ammonia lyase"
                     /protein_id="HBK3210670.1"
                     /translation="MSSIFEKYSVRRVINASGKMTILGVSTVDKEVIEAIGEGCKNFF
                     IIEELINKTGEYIANLLGCESALIVSSASAGIAQSVGAMIAKDDMSLVYNVNNPKKQV
                     KREIIIPKGHNVDYGVPVEVMIRLGGGEVVEAGYANMCNKEHIIREINENTAAIMYIK
                     SHHCVQKSMLSVLDAVQVAKEYNLPLIVDAAAEEDLNVYYELGADLVIYSGAKAIEGP
                     SSGLVIGKKKYIDNVKLQSKGIGRAMKIGKENIVGLTCAIERYISNDKVTLKEMEDKL
                     NPFIDKINTIKGVSASITRDSAGREILRGEIDFNEDIINKSTQQIINELRSGEIAIYT
                     RDYKANEGKIEIDIRSVTGSDLDTIYNRIKNIVES"
     gene            complement(100284..101417)
                     /locus_tag="KOU88_000758"
     CDS             complement(100284..101417)
                     /locus_tag="KOU88_000758"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase/deacetylase family
                     metallohydrolase"
                     /protein_id="HBK3210671.1"
                     /translation="MKIDILIKCGKTVDKSIIDIAILDDKIIEVKNQIDDSKYQANQI
                     INLDGEKFISAGWIDIHTHCYERLDLYKDYPDEVGIKSGVTTVVDAGTTGALDIGKFY
                     EDTKKYKTNVYALINIAKQGITSQDELSSMMNIDEYELRRAVKKYKDFVVGIKARMSK
                     SVVISNDVEPLKVAKRIKNELNLPMMVHFGSSPPTIEDIFDYMEKGDILTHIYNGKPN
                     GILRGNEVKKEIIEARERGIILDVGHGTESFSMDIAMKSKDAGIFPDTISTDIYIKNR
                     INGPVYNLSTTMEKFIYMGYSLEDIIDKVTKNAADAISLKNKGLIKEGYDADLTIFDV
                     VNEEKELQDSLNKSVITSTSIKPRAVVVNGEYLNIGKSIGENE"
     gene            complement(101419..102513)
                     /locus_tag="KOU88_000759"
     CDS             complement(101419..102513)
                     /locus_tag="KOU88_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBK3210672.1"
                     /translation="MERRLGISVYPEHSNMEDDKAYIKMASKYGFKRIFMCMLSITRP
                     KEEVKKHFKEIITYARELGFEVILDIAPNIFDILQISYDDLTFFSELNASGIRLDYGY
                     DGSKEAMISFNPYDLKVELNMSNDVAYLDNIITYKPNVNNIYGCHNFYPQRGTGLPYD
                     FFVRCSNRFKKYGIRTAAFVNSKYATIGPWNINDGLCTLEMHRNLDIATATKHLFATG
                     LIDDVIVGNAYASEDELKRMSEVNKYQVVFNVVTEEKTSEVEKTIMANEQHFRRGDIT
                     NQVARSTEVRKKYAKENFPKHDNTTIFKRGDVVIGNDDFGKYKGELQLILQDCADERK
                     NKVGRIKEDEIILLDFIEPWSKFKLILEGE"
     gene            complement(102650..103951)
                     /locus_tag="KOU88_000760"
     CDS             complement(102650..103951)
                     /locus_tag="KOU88_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3210673.1"
                     /translation="MEKFASFLERKIMPVAAKISNQRHMRAVRAGIIATLPLTIVGSF
                     FTILLNIPIDAYMDFIAPFKAILDIPFRYTVGFLSLYATFGIASSLAKSYDLDTTGVG
                     MLAVMAFLVSTIVPTQVVEPVGGVIEAGRWMDMAKLNSPSLFGAIVTSLITVEIYRFM
                     KEKNITIKMPAGVPVEVSNSFTALLPTAVILMLFWVIRHILGFDISVALSAMLSPLKG
                     FLSGNSLGGGLLTVFLITLFWVLGIHGPAIMGPVIRPIWDMSIAENITAFTEGVSAHA
                     MPNIFTEQFLQWYVWIGGAGATLALVVMFMFSKSQYLKSLGRLGFLPGLFNINEPIIF
                     GAPIVMNPILGIPFIIGPIIMTILSYVLTITGVIPMMVARLPFAMPAPIAAVMSTNWS
                     ILAGILVLINFVISFAVYYPFFKVFEKQQLQREQEEMSENL"
     gene            complement(104175..104876)
                     /locus_tag="KOU88_000761"
     CDS             complement(104175..104876)
                     /locus_tag="KOU88_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3210674.1"
                     /translation="MLRNQPLYIQVVDILKQKILNNEYKIDENIPTERELEQEFGVSK
                     ITIRKAIEILESEGYVEKKSGKGTKVISNSLFNKLSKAESFSSILLSKGHKLSKETIS
                     IEKIINDTNSQVFSIFGEKCSKITRMYYLDSKPYIFFTHYIPFDENLTVESFNNESSL
                     YMYLYRRNINITRFEDEFFIEESELEVSKALNLAKDILLGRKRKTYDENDNIVELSFA
                     RYNTEVQNYVIKYEI"
     gene            complement(105089..105406)
                     /locus_tag="KOU88_000762"
     CDS             complement(105089..105406)
                     /locus_tag="KOU88_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK3210675.1"
                     /translation="MDEKTIEISFNIIGYAGEGKGLAFEAIKEAKNGNIEKAKELLKE
                     SREVINKAHRYQTELIQNEASGNRTEISVILIHAQDHLMNGMNFQQLAEEIVDLHLKL
                     QDK"
     gene            complement(105454..105765)
                     /locus_tag="KOU88_000763"
     CDS             complement(105454..105765)
                     /locus_tag="KOU88_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210676.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMESAAKENGIESQIWAIPESTIQN
                     EIEKCDVLLLGPQVRYVLPKAQEIAKPYNIPVEVINMMHYGTVNGEAVLNRAIELNNT
                     K"
     gene            complement(105914..106393)
                     /gene="rlmH"
                     /locus_tag="KOU88_000764"
     CDS             complement(105914..106393)
                     /gene="rlmH"
                     /locus_tag="KOU88_000764"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBK3210677.1"
                     /translation="MNISIVVVGKIKEKYLKLGIDEFKKRLSKYCKLEIIELDDEKAP
                     ENLSVKEMEIIKDKEGKKILGKIKHNSYVIALAIDGKGLSSEELAKTMSDLAVRGNSS
                     LCFIIGGSLGLSDEVLGRADYRLSFSKMTFPHQMMRLILLEQIYRAYRINNGEPYHK"
     gene            complement(106461..108563)
                     /locus_tag="KOU88_000765"
     CDS             complement(106461..108563)
                     /locus_tag="KOU88_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC/EAL
                     domain-containing protein"
                     /protein_id="HBK3210678.1"
                     /translation="MLKRNFENVEDNKILYSIKQGMILAIPAIMTGSTALVILNLPIK
                     AYQEYLSGLFNGEVTNILNFINDSTLGIISLIILLTISYSYGKIYGSKYTVLVPIVAM
                     CSFLVFSHGNELNSYIEIFKTKWLFTSIIVSMTSSVLFVKLTESFVTSVKFHTEGADA
                     DFNMVVSAIVPFIIVVFLFSIFRVVMISLIGSSNFQDIFYNLFSNVFNKMGTNLMSAL
                     LFIFLMHFMWFFGIHGSNVLDTVAKNLFENSMAININLVNNNQLPTEIFTKTFFDTMV
                     LLGGCGSLLCLVIAIFLSEKRINVRKLAKIASIPALFNINEMLVFGIPIVFNYIMFVP
                     FVITPIILTVTSYVAMSTGIVPCTVSAVEWTSPIFLSGYMSTGSIRGSLLQVFNLCVG
                     VMIYIPFIKMSQNRYTYMFKNNIENLTNLLKRYELTGEQPNLLNHNGKIGSISKMLAS
                     DLKFAMKRGEIELFYQPQVNYNGNVVGAEGLLRWKHSIGGFIYPPLVIILAKEEGFLD
                     ELGEYIINKACIDLKKSEKLLRNPVKFSVNISPDQLDDPKLPEQIKNIISSNDINPNM
                     LGIEITEQIALSGSQIIIERINAIHNLGIKLIMDDFGMGHSSLIYLQNNNFDIVKLDG
                     SLVKEILTNKRSSEIIMTIVNLSKNLDFDIVVEYVENIDQRDKLYGLGCEIYQGYYYS
                     KAIPFEEFVEYANQEREI"
     gene            complement(108576..109373)
                     /locus_tag="KOU88_000766"
     CDS             complement(108576..109373)
                     /locus_tag="KOU88_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3210679.1"
                     /translation="MLKYCSVGSGSSGNCHYIGYKNTNILVDAGLSGKRITTGLKDIG
                     VDADKLKGIFITHEHVDHIKGAGILSRKFDIPVFANIKTWCSMKDKLGDIKDKNMKVF
                     ENDKTYSLGDIIVRPFSIEHDASDPVGYNFYTESDEKMSIATDIGCITQNIKKHLYKS
                     KLVVLESNYDPNMLMMGSYTYALKKRVMSSTGHLSNEDAANFCVELINEGTESILLAH
                     LSKENNFPELAYETSKGVLASNDIVVGQDVKLDVLSRNDVSNVYEMK"
     gene            complement(109475..110938)
                     /locus_tag="KOU88_000767"
     CDS             complement(109475..110938)
                     /locus_tag="KOU88_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HBK3210680.1"
                     /translation="MVIKFNQKVRRTLSVAILFMVLIIGCFIEKDDSLETYKEKTNSK
                     INQYNMDVIFDDETKRLMCNQNVDYINNTKSNIDKIYFHIYPNAFSKKDFAPFEKSEM
                     TRAYPNGFNEGYIDIKNILNNNSKMEYKIKGDKNDILEIELGKELKPNERMSLDIKYN
                     VKIPNSIGRFGYGENTINVTNWFPIACVNDERGWNLKSYETIGDPFYSETSDFHVKLL
                     IPNKYKIAHTGKLIDDKHDNKKMLYEIEAENVRDFAFILSSKFDVNKVDSKGVAINTY
                     NLNKKLSKKATEVAKDSINIFSELFGKYPYKEFSVVASDFFIGGMEYPMLVMIDQSLY
                     NEKNEFLLEYVIAHETAHQWWYSAVGNDEISEPWLDEALTEYSTIVYFEQKYGKDMAN
                     KLIKTMEIQTKSYLSENIFKPANEYKNSTEYSLNVYTKGAIAFNEIRKEVGDKVFFET
                     LNEYYNKYKHKNANGRAFVELWNSKGVDINKIISECK"
     gene            111063..112121
                     /locus_tag="KOU88_000768"
     CDS             111063..112121
                     /locus_tag="KOU88_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBK3210681.1"
                     /translation="MFFKESNEIDLGEITIPNIFIDIFMPMADGLYVKVYLLGYRQAC
                     DITSNPKFDNNSIAKNLNIPLSDVLSAWKFWEEKKIIKIHDNEEYDNFNYSIEFLDLK
                     NFYIENILSNNSSIKSNTDKVVSTSENPSIRKMFNSINKIVGRYLDPSEKMSIMDIMN
                     KYNMSPDMILCAYEYVKDKTGTSKPVKYIEGIIRNWYDSNLYTPKDVEESFLVRSERY
                     ILYKTIFNELGFSRQPSKSEKELMDTWFDKFNMDIDLIINACSKSKNISNPSISYING
                     IIKNWNEKNIKNLNDLKQKEEERIVKENINKKQINTTQNNNTYKKTKFHNFNETFTQY
                     TSDELDEIIKKSQKEKFK"
     gene            112130..113122
                     /locus_tag="KOU88_000769"
     CDS             112130..113122
                     /locus_tag="KOU88_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210682.1"
                     /translation="MNEDKIRKILAKYAKRRDDNELLLEHRKNEVYNRIPEIKSIDDE
                     ISKIGLSLAKIVLLNPKSKDEIVKKTKENIESLKVKKERLLAESNIPLDYLEIKFQCI
                     SCKDKGFLPNGEKCSCLKQEIVNEAYKMSNLDRILSQENFSNFNLNIFSPKKGSDGEI
                     SPRENMLNNLSICENFVHDFKKDNSENLLFYGSTGLGKTYMCNCIAKELLDKGNVVIY
                     QTSFRILDILEDYKFRRDTNNQISEDNYKNLFDCDLLIIDDLGTELNNSFTSGEIFNI
                     VNTRLVAGKKIIISTNLTPSQIGNTYTQRTLSRILDKFRILEFTGDDLRWERFK"
     gene            complement(113505..113579)
                     /locus_tag="KOU88_000770"
     tRNA            complement(113505..113579)
                     /locus_tag="KOU88_000770"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113545..113547),aa:Thr,seq:tgt)
     gene            complement(113613..113688)
                     /locus_tag="KOU88_000771"
     tRNA            complement(113613..113688)
                     /locus_tag="KOU88_000771"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113653..113655),aa:Val,seq:tac)
     gene            complement(113693..113767)
                     /locus_tag="KOU88_000772"
     tRNA            complement(113693..113767)
                     /locus_tag="KOU88_000772"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113732..113734),aa:Glu,seq:ttc)
     gene            complement(113774..113849)
                     /locus_tag="KOU88_000773"
     tRNA            complement(113774..113849)
                     /locus_tag="KOU88_000773"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(113814..113816),aa:Lys,seq:ttt)
     gene            complement(114175..115464)
                     /locus_tag="KOU88_000774"
     CDS             complement(114175..115464)
                     /locus_tag="KOU88_000774"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBK3210683.1"
                     /translation="MKTVAIVGSQWGDEGKGKVIDYLATQADVVVRGQGGNNAGHTLV
                     VEGKKYALHLIPSGVLNPNTVNIIGNGIVFDPKGFLEELEMFKTDNISTENIKISDRA
                     HVIFPYHKELDALSEEARGDLKIGTTKKGIGPCYMDKTERSGIRICDLMDKDKFAIKL
                     KAQIDAKNEIVKNIYGKEELFDFETIYNEYLGYAEQIRKYVADTSVIVYDAVRAGKKV
                     LFEGAQGTLLDLDLGTYPFVTSSHPTSGGFAIGAGIGPNMIKDVVGIVKAYTTRVGEG
                     PFVTEQINETGDKIREQGHEFGVTTGRPRRCGWFDAVIVKYAARVNGLTSISFMLLDV
                     LTGFDKIKVCTSYKMGDKIITDFPASLDDLAKCEPVYEELDGWNEDITQIDNFDDLPE
                     NAKKYVAKIEELVGVSVDMVSVGPNRAQTIIRRNIFA"
     gene            complement(115546..115854)
                     /locus_tag="KOU88_000775"
     CDS             complement(115546..115854)
                     /locus_tag="KOU88_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011862026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210684.1"
                     /translation="MEKISLKYIYPNIIKVLDEINLFRVIDNNLRESIVVYANNVDNQ
                     YHINMTNTNFGNIINICKLEKLLDVDKFMEKVIKYEKEIIEKEEFSKIEEYMLNIGEY
                     "
     gene            complement(116059..117387)
                     /gene="dnaB"
                     /locus_tag="KOU88_000776"
     CDS             complement(116059..117387)
                     /gene="dnaB"
                     /locus_tag="KOU88_000776"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBK3210685.1"
                     /translation="MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKE
                     AHKIIYECMITLSNKGEPIDLITLTEELRKQGHLNDIGGISYITSLSTIVPTTSNVKY
                     YADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
                     NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFS
                     LNLVQNAALKGDASVAVFSLEMSKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIID
                     AMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYLQLMEGEGNNESRQQ
                     EISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMF
                     LYRDEYYHADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL"
     gene            complement(117406..117855)
                     /locus_tag="KOU88_000777"
     CDS             complement(117406..117855)
                     /locus_tag="KOU88_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBK3210686.1"
                     /translation="MKVILLKDVKGTGKKGEMKEVSDGYARNFLFPKKMAVQADSVAI
                     KELNEKNKSKEIKAQKEYEEAVLLGKQMEEINIEIYSKAGEGGRLFGSITSKEIAEQL
                     KKQKDIDVDKRKILLDEPIRSLGSTFVEIKIHQKVTTKIRVDVKEKQ"
     gene            complement(117856..119850)
                     /locus_tag="KOU88_000778"
     CDS             complement(117856..119850)
                     /locus_tag="KOU88_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBK3210687.1"
                     /translation="MSNKQTFKLNMPEINLYIIVIGISSIILLYYNLYVGCLFFCIFV
                     YMVFHNWRTTNIRRHEWTEYIQNLSLDIDETTKKAIINLPIPLCILEFDGNISWYNGK
                     FYDMIGQKDLLDKNIEDIVKNLNLRKVLNENKEMYTEINYKEKEYTIIYNVIKNDQEK
                     NPKYLMILYWIDKTEYLKVKQNYDDEKNAMMLIQVDGYDEVLKSAAEDKRALINVEVE
                     KILSALELNSNGALRRTSKDKFFLVMHKKELKKLEAEKFSILDTIRHIDYGNNLPVTI
                     SIGIGIDGDTLNENLKLATGALDLALGRGGDQAVVKTKDKFVFYGGKSKAVEKKTKVK
                     SRLIGHALREVIQQSDQVYIMGHKYPDMDAMGAAVGVYDICKSCNKTANIVLQSVNES
                     IEIFINKINENNYYKKLFIGKEEAIDNCTKNTLVVVVDTHRPNYTECEELLKLSEKVV
                     VIDHHRRGVEFINDAVLLFHEIYVSSTCEMVTELVQYMDEDVTINKLTAEGLLAGISL
                     DTKNFAFKTGVRTFEAASYLRKVGADTIEVKKFFNSDVKDFIIKAEIIQSTKIINNRI
                     CLAYSSTEIDSINVIIAQTADELLNIKEVEASFVLGEKDDTIFISARSLGQINVHVLM
                     EKLGGGGHIDIAGAQLKNVSLKEAYKMVNKIIEEYLEEEE"
     gene            complement(119861..120817)
                     /locus_tag="KOU88_000779"
     CDS             complement(119861..120817)
                     /locus_tag="KOU88_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HBK3210688.1"
                     /translation="MNNKIRLSKAMSIIVLAIIIALVIAYIPMLGIFSMLAAVPYVII
                     GAITDRKYSLISILVTFCVLILFADISYALNICIMYSLPGIVIGKMLKRSFEQEDSNK
                     FEPIYGGTIIFVLSMLVYFFVLKTFLNVNLLDEVSKMISEIVNIQKNSFSATELKVFD
                     KMKPDEIVSYFTNMLPMMLFLQGLLSAFVTYYLSVFFIKRITKMNIRFPKFADFYLPG
                     NAILTTFLLYLLVLFIQIIGSKLYTELIMTNLQLVFNLMFVIQGIAVCIYFLKKWIRQ
                     GPNKIMFFSGIILCLFGFMGISFVGMVDSIIDFRKVRSYKST"
     gene            complement(120825..121145)
                     /locus_tag="KOU88_000780"
     CDS             complement(120825..121145)
                     /locus_tag="KOU88_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBK3210689.1"
                     /translation="MKIDKGSEITRNIKIIEWMKTEILMSVSDLFNLLFKGVKPLDEA
                     IQDTLANIIMITYLLAKRLGISFRDVDYKVKEKIKIGIDEDHSVERWYGDLSNLKKHM
                     DNRE"
     gene            complement(121288..121515)
                     /locus_tag="KOU88_000781"
     CDS             complement(121288..121515)
                     /locus_tag="KOU88_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBK3210690.1"
                     /translation="MMNKKRRKKKRVCQFCADKNAKIDYKSTQRLQKYITERGKILPR
                     RISGTCAKHQRELTVAIKRARNIALLPYTLD"
     gene            complement(121534..121968)
                     /gene="ssb"
                     /locus_tag="KOU88_000782"
     CDS             complement(121534..121968)
                     /gene="ssb"
                     /locus_tag="KOU88_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK3210691.1"
                     /translation="MNQVVLVGRLTRDPELRYIPGTGTPVASFTIAIDRDYVKKDGSK
                     ETDFIPVEVMGKSAEFCANYITKGRLVALQGSIRVDNYQTQSGEKRTFTKVSTRSVQA
                     LDSKNKSENSYRESAPAFEPSFEPQGLDPQGFQAIDDDDIPF"
     gene            complement(122005..122283)
                     /locus_tag="KOU88_000783"
     CDS             complement(122005..122283)
                     /locus_tag="KOU88_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBK3210692.1"
                     /translation="MRNYELVYVVKPNSDEEVREAILNKVKEVVATDGEIVKVDTWGT
                     KKLAYPIAKFTEGFYVLVNFKSAVDVPKEIDRNLKINENVIRHMIVVA"
     gene            complement(122497..123693)
                     /locus_tag="KOU88_000784"
     CDS             complement(122497..123693)
                     /locus_tag="KOU88_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK3210693.1"
                     /translation="MAVKYAKRMQGLQGSEIRELLKLTQQPQIISFAGGMPAPELFPV
                     EEMKKVSVAVLEENGRSAMQYTTTEGYEPLREKIAARMNDKNKTNVNKDDILVTSGSQ
                     QGLDFAGKVFIDEGDVILCESPSYIGAINAFKSYQPKFIDVPTDSDGMIMEELEKILE
                     TTDRIKMIYVIPDFQNPTGRTWPLERRKKFMEIVNKFEIPVIEDNPYGDLRFEGETLP
                     SLKSMDTKGLVIFLGTFSKIFCPGYRLGWTCASPEILSKFNFAKQGADLQASTISQME
                     VSKFMDMYDLDAHVDKIKAVYVKRRDVMLKTMEEEFPEGLVFTHPEGGLFTWVELPSN
                     LNAKELMPKCLDKNVAYVAGGGFFPNGGRENTFRLNYSNMPEEKIIEGIKNIAAVLKE
                     AMGVEA"
     gene            complement(123796..123981)
                     /locus_tag="KOU88_000785"
     CDS             complement(123796..123981)
                     /locus_tag="KOU88_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBK3210694.1"
                     /translation="MPMDLKIGDIVELKKQHACGCKEFEIIRTGMDIKIKCTKCSRLI
                     MLDRETLEKRVKKLIKK"
     gene            complement(123996..124259)
                     /locus_tag="KOU88_000786"
     CDS             complement(123996..124259)
                     /locus_tag="KOU88_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBK3210695.1"
                     /translation="MNQMYIVSFNSTHHAIRSEKLFGENSLKVMALPTPREITASCGI
                     SIKFSFEDMEKIKTILVENNVDIKGIYCISKLENGSKEVEKLD"
     gene            complement(124332..124934)
                     /gene="yedF"
                     /locus_tag="KOU88_000787"
     CDS             complement(124332..124934)
                     /gene="yedF"
                     /locus_tag="KOU88_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBK3210696.1"
                     /translation="MSIKIDARGLACPKPVINTKRELDNLEEGVVVTIVDNETAKENI
                     LKLAKSLSCEANIVDEKENFISIEIRKGKNILDKQNVVDNKESELDNTCIFISSDKMG
                     LGNDELGKVLIKGFIYTLTESKPYPKYVLLVNGGVKLSAENEETIENLKILENMGVEV
                     LSCGTCLDYYNLKDKLQVGTVTNMYTIVETLKNASNTISI"
     gene            complement(125039..126331)
                     /locus_tag="KOU88_000788"
     CDS             complement(125039..126331)
                     /locus_tag="KOU88_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK3210697.1"
                     /translation="MEILSLGEKIKKLRKEKNMTLKELAGDRITAAQISHIERDKSHT
                     SYELLEYLGDKLDVSVEYLLETKEMQSKKITDNLILQSEIYIKENELNKAEDQIKEVL
                     DICKRYDLMENYGRCNFLMANINLKKSNYNDAIENFEKALYFFIKNSDSENILKCYLN
                     IGKIYMQEDFYKGAISHFNFAEEILSENKFEDVNIHKELYSKMAYCYIKLDNPNMSLK
                     YIEKINEIDNRNDRKEDVDILVLKANNMLEIGKYEESRDYFKKALKILESEDNKTGLA
                     NVYLTICDVYRKIGETDRVLEYSQKVYDIKKNDEDEYMMSGLFKIIEAYIDKEDYDLA
                     RKYCKIALASSIKNKNKFNEYKALRFYANMYKNQNEVTLAIEYLIKCIKIVSDLGNNR
                     ILANLYIDLGQLYSNISKEKELEYYQKGVFMYKNLEIM"
BASE COUNT        40382 a        22752 c        13624 g        49575 t
ORIGIN      
        1 ttatgtttgc ccttttctta aggacaagta atactatatc accttaaaaa taattcgtca
       61 atactttttt tgttttttat tttaaaaaag gttataactt ttggtttttt ttaataaata
      121 taattaaaac taatagatat aacccttgat attacaaaca atgcatgcat atataatttt
      181 acctattttg caattttatt ttcataagaa tatgaattag ctctcactct atctgcccaa
      241 acatttatac tcttaacttt attaacatta gttgtaccct caaaaatatc cattgcatcc
      301 ttacaaaaat atatcataac atcaagaacc aaaaatccaa cacaaaataa acataaaaaa
      361 ttaattactt gaaacatcag acattccccc aataattttt tatatatagt attctcataa
      421 attattcttt ttaccttctc ataaattatt ctaaatattt tcataataaa ttactttcaa
      481 tcatattttc taaatataaa gtctcaatca acaaaaacta atatcaattt ctaacgtttg
      541 ttggtaattt ataaattaaa tatctaaaag aatctttgaa gcatataaaa agcattctac
      601 taagttttaa ataaaattta gctatttatt gataatttaa tagctaaact ttatttaaaa
      661 cttagtagaa tgctaatatt tcttagtttt cttcttcttt atttggattg ttatcaatag
      721 gtttcatagt cgggaataat aatacatctc ttatagatgg agagttagtt aataacataa
      781 ttactctatc tatacctatt cctagtcctc ctgtaggagg tagacctacc tctaatgctt
      841 ttaagaaatc ttcatccatt tcaaaagctt catcatcacc taattctctt tttcttaatt
      901 ggtctataaa tcttcctttt tggtcaatag ggtcattaag ttcagaaaat gcattagcta
      961 actcccactt attagcaaat gcctcaaatc tatcagttct tcttgggtct tcaacatttc
     1021 tcttagataa tggagatact tcaactggat gatgagttat aaatgttggt tggattaatt
     1081 tatcttctcc aaattcttca aagaaagcat ttattacttc tcctcttctc attccaggtt
     1141 ttatctctat acctttttct ctagcaactt ctagtgcctc ttcatctgta tttatagtag
     1201 aaaaatctac accagaatat tctttaacac aatcttccat actcattctt ttccaaggtg
     1261 gtgtaaagtt tatttctgtt ccttgatagt taactatcat acttcctgta gcaacttcag
     1321 ccatatgtgc aataacattt tctgttattt ccatcatatc agtatagtct gcatatgctt
     1381 gatataattc tattgcagta tattcaggat tatgttttaa atccatacct tcatttctaa
     1441 acattcttcc catttcataa actttatcaa atccaccaac aataagtctt tttaaataca
     1501 attcattcgc tattcttaaa tacattggta tatgtaaagt attatgatta gttataaatg
     1561 gtctagcatt tgccccacct gctatagtat ttaatattgg agtctcaact tctaaaaatc
     1621 ctctatcatc taagtatgct cttaatgctt ttaatgcttt tgttctaatt aaaaaagcat
     1681 tttttacttc tggatttact attaagtcaa catatctttg tctatatctt agttcttggt
     1741 cttttaatcc atgatatttt tctggtaaaa cttgtaaaga tttacatagt aatactacag
     1801 atttagcctt tacagatatt tcaccttttt tagttttaaa gatttctcct tcaattccaa
     1861 ctatatctcc aatatcatat gttgaaaata cactatattc ttcctctcct atagcatcta
     1921 gtcttacata agattggatt cttccctctt ggtcttgaat atctataaag ccagctttcc
     1981 cttgtattct cttgctcatt atacgtcctg ctatttttgt agttttaccc tcaagagaat
     2041 caaagttatc ttttatatcc atagaataat gagttctatc atatctactt tctttaaaag
     2101 gatctctacc tgactcttgt aattttttta gtttatctct tcttacttga agtacttcac
     2161 taaggtcttc ttgaatttgc gcttcttcat tgctttgttg attatttttc atttttttcc
     2221 tccaaattat cttcttattt ctaatatttc aaacttagca actccatcag gaacttgcac
     2281 ttccacaact tctttcgcag ctctacctaa aagtgctttc cctacaggag attcgtttga
     2341 tattttacca tcatatgggt ctgcttctgt cgaaccaact atagtatatt caacctcttc
     2401 atcaaattct aaatccttaa ctttaactat tgatcctatt gtaacaacat taaggtctat
     2461 tttgctttca tctatgataa cagcttttct aaccatattt tctaatttta aaattctttc
     2521 ttcaacttgt gcttgttcct ttttagcttc atcatactca gcattttcag ataaatcacc
     2581 aaaagatata gcaactttta ttctctctgc aacttctttt ctctttacaa cctttaagtt
     2641 ttctaattct tcttctaatt tatcatatcc ctcttgtgtc aataaaaact ctttattttc
     2701 ttccattata aatacaactc cttcacaaat ttcttaggaa ttttcctaat tatattttaa
     2761 aaattttata atcttttttt aatttatgcg ctatattata agtcactatt atttttatgt
     2821 caaggagtct tccatatagt actccaattt cgacacaact tcttgatagt cttctatttt
     2881 gttaatttca tcccttaatt ttgcagagtt tctaagtcct tttaaatacc aagcgatgtg
     2941 ttttctcatt tcccttacag ctacatactc tccatgttct tctactgcaa gttttaaatg
     3001 cttaatggca gtacttattt tttcgttaag agttggctct ggcaaaatct cgcctgtatt
     3061 catataatgg tttattcttt taaatatcca agggttacct tgagcacccc tacctatcat
     3121 tatagcatca caaccagttt tgtctaacat atttattgaa tcttctattg taaatacatc
     3181 accatttcct ataacaggta tactcaaatt tttcttaatc tctgcaatta tatcccagtc
     3241 tgctttgcct gtataaaact gttctctagt tcttccatgt attgctaaag cacttattcc
     3301 acaatcctct gctatctttg ctatttcaac agcatttaca ctattatcat cccagccttt
     3361 tcgaatcttt aaagtcactg gcttttttga gttcttcact actgccctca atacctcttc
     3421 tgcaagctta ggatttttca taagtgctga accatctcca tttttaacta cttttggagc
     3481 tggacacccc atatttatat cgagaatctc atttgaataa tcattcatta tctctgctgc
     3541 tcttcccata aactctggtt ctgaaccgaa tatctgaact gctacaggat gttcttcctc
     3601 ttctatctta agcatttttt tagtattttc atcatcatag caaagtgcct taccatttat
     3661 catttctgta tataaaagcc cacatccctg ttctttacaa attaatctaa atggaaggtc
     3721 tgttacacct gccataggtg atagaaaaac tttatttttc aattctaaat ttcctatttt
     3781 cattgttttt ctcctatttt tgcctttatt ttgtgattta actttaaatt cttatttcct
     3841 cattataata taccacatat agctagaaat ctatcataaa aagggaattg gatatataac
     3901 ccaattccct gtatattaat tattcttggt ttttttcata tattattctc aatccttcta
     3961 gtgttaaaaa accatctaca taatctatac ttttcgtctc tgaagcaatc agtttagcta
     4021 atccacctgt agctataacc ttaacatcat cacaattcaa ttctttcttc atcatactta
     4081 ttattttgtc aactaaacca acatatccat aaattattcc agattgcatg gctgatacag
     4141 tactcttaca aatagtcata cctggcttag ctaattctac tctaggtaat ttagacgcac
     4201 tttgaaataa cgcctcacta gatattttta ttcctggtgc tattgttcca cccaaatatt
     4261 cacctttttc agagatagca caaaatgtag ttgctgttcc aaaatcaaca agtatacttg
     4321 gtgctccata cttttctatc cctgctacag cattaactat tctatctgcc ccaacttgtt
     4381 ttggattatc atattttata tttagacctg tttttatgcc tggacctact attaatggtt
     4441 gttttttaca gtactttata caaaagtttt caagagaatg cataacattc ggaactacag
     4501 atgatattat aacatcatca atatcactta tattcacatt atcataatca aataggttac
     4561 ttatcaggat tccatattca tcagacgttt tttccctatc tgttttaatt ctccagtaat
     4621 taactaattt gtcaccttta tatataccta aaaccatatt agtatttcca acatcaaata
     4681 ctagaagcat atgtcattaa ccttctttct attttttgct tttcttaagt acagtggcaa
     4741 cagcagctac tactaaagcc cctactattg cttctggcac cccatttgct gcggcaagag
     4801 ccattattac ttttcctgct gaaccacttt tacccattgc atgaagatac ttgtcagcat
     4861 ataagacata tatcattcct aaaactccag ctgtatttaa cagagaacct attgcccctg
     4921 taattaaacc tgatatgtat accttatttg tagccttaat tattaactga tatacataat
     4981 aagctaatac acctatcata actcttggta atattgaaac taatggattt ataaaaacaa
     5041 aagatgttac tgttgggttt gttatagcat ttaagagact tgatatccca aatataaatc
     5101 ctattgctgc cccaactatt ggtccttcca taatagctcc aataataact ggtatgtgca
     5161 ttatagttgc ttttgtaggt ccaactggaa taaatcccaa tggagtcata gatagcataa
     5221 tagaaatagc tgatagtact cctattatag tcatctttct tacatttact tttcttactg
     5281 atgcacttgt gttcatcata aaaaatacac ctccgttcca gctcattaag atgccggact
     5341 acttaatttt ttaatttttt tcgttttttt cttataacta tgagtcaagc taccattgta
     5401 ggatgcccgc tctaacaaga ataattttat caagatgagt tgccattgtc aacaatttga
     5461 caagaaaaat atgctaattt catcatattt ctcgtttttt tactatatct ttatatgcca
     5521 ttatattttc tacactatcc gcttttttta ctgcatttat tatacttttt tccacaacct
     5581 ctacagccaa tgaacctact aatgttatat ctgcttctat ttctcctgtt gatattgtga
     5641 atattgtatc tccatcatga ggtgtatgga taggaaaaat agacttagca tatccatcat
     5701 gtcccatttg agatatcttt ttacatccag ctttggttaa cttagcattt gttgcaatta
     5761 tcccaattgt agtattatct acactaaatc cacctttact ttcaccttgt ttcattaatt
     5821 tatatgtatc aattgtttct gtccttttat catttaaagc accagctata accttaccat
     5881 tttcataaac atctccaaga gcatttacag caattaatgc agatacaatt agaccattat
     5941 ctaattttat agaatagcta cctattccgc ctttcatagc atattcctga cctcttatct
     6001 ttccaacagt ggctccacaa cctgctccat aatttccttg atttaaaata tcagtatttg
     6061 caacttcaca agctctataa cccatcttta aatctggtct acatttaaag ctccctactc
     6121 ctaaatcaaa taaaactgct cctacaacta taggcacttt acctacacct acatcaaagc
     6181 caattccttt ttcttctaag tatctactta caccacaagt ggattcaaga ccatatgcag
     6241 aacctccagc caaaactact gcatgaactt tttgaaccat atttacaggg tctaataaat
     6301 cggtttctct agtccctgga gcagagcccc ttacatcaac accgcaagta gctccttctt
     6361 cacatattac tactgtgcac ccagtaagac catttctatc ctcaatctgc ccaaccttta
     6421 agccttctat atccaaaata ttattataca tatccttttt ctcctcttat agaaacttcg
     6481 cctgaaataa tttcttttat acttccatca cttctttgaa ctaataaatt tccctcttca
     6541 tttatgtcta aacatttcac tagttctcta ttatctcctt ttaatacata tatattttta
     6601 tctataattg cagaataatc tctacatatt tttaaggttt tttctttgga attatttaca
     6661 gtataatcta aatataattt ttcaaattca gtcaatacat tcctaacaat atctactctg
     6721 gataacatat atccttcttt atacaatgat gtggctttgt cagctatttc ttgttcaaaa
     6781 tccattattt taacatttat tccaattcca agaacaacat aatttgttct ttcaatttca
     6841 gcagataact ctgttaatat accacatatt ttttttccat ttaaaataac atcatttggc
     6901 cattttatta atgtatttgc tcctagattg tttaaagctt tcgttacact tgctcctgct
     6961 attaaagtta taaatggagc tttgaatggt tccatatctg gttttaatat aatactcatc
     7021 cagattcctt catgaggttt tgaattccat cttcttccca atcgtccttt ccccatatct
     7081 tgatgttcac ttaaaatcac agtcccatct acactattta tagctatcct tttagcatgt
     7141 tcatttgttg aatctatagt gtcaagatgt tcaatatttt ttccaataaa atctgtatct
     7201 aatttatagt aaatattctg tggacttaat aaatcagttg gattttccgc taatcgatac
     7261 ccttttttat ttacagattc tatattatat ccctcttctt ttaaggcttt catatgtttc
     7321 catatagctg cacgtgacac ccctaattgt tttgataatt cttctcctga aataaattca
     7381 gatttattat ttaatataat ctctattatt ttatctcgca tatttcacct ctaatatgac
     7441 ataatttcat gacttatttt cttctaataa ataattatac attattaata tacttttaat
     7501 actattaatt ttaaatttcc tttttaatta ttataatggt tgttttatat tttatattga
     7561 tgatttatat aattttacat tttatttaaa taattttaaa ataataaaaa aactgaaagt
     7621 atcaattaaa ttaatacatg caaatataat ttgcttatta atttaatatt atactttcag
     7681 ttttagtatt taatccacat cagataataa tcctaaaatg accaaggtct taaaactatt
     7741 tatctttatc agatttatct tctaaatttt tatttatatc aataacattg tttctttctt
     7801 cttcatcttt ttctaatttt atagttaatt gttcttcaac ttctttagaa gaattttcct
     7861 ctgtaactgc attttcaatt tcattcagag gtaactcttt attaaatgct tttacaaatt
     7921 gttctgcatc taaagtttca tatataagta aagcttgtgc tacatactct aatctatcca
     7981 tattttcttg taatatactt cttgtcttat catatgcacc atcaactata cgctttgttt
     8041 cttggtctat ctcaaaagca acttcttcag aataatttct cttacttgaa aaactattac
     8101 ctaggaatac ttcatcatca ctgtcaaatg acattggacc aagtttagaa ctcattccat
     8161 actttgttac catacttctt gcagtagctg taactctttc taagtcattt gaagcacctg
     8221 tagatacatc cttaagtact agctcttctg ctactctacc accaagtaaa actacaatat
     8281 tttctttcat ttcatttttt gtagcataga acttatcttc aacaggaagt tgcattgtaa
     8341 accctccagc tcttcctctt ggaactattg taacttgatg aacaggactt acttcttcaa
     8401 gtacatgggc acaaactgca tgccctcctt catggtacgc tgtaagtctt ctttctttct
     8461 cacttattac tttcgatttt ttagccacac ctgctataac ctttgttata gcttcttcta
     8521 tagtttccat cttaattttc ttttctcttt ttctagctgt taatattgca gcctcattca
     8581 ttaagttctc tatatcagca ggagtaaatc ctggtgttct tctagccaag acatccattt
     8641 ttacatcatc acttaatggt ttatttcttg agtgaacttt aaatatagcc tctctacctt
     8701 ttacatctgg tgtaccaaca acaacttgtc tgtcaaatct tcctggtcta agtaaagctg
     8761 ggtcaagtat atctggtcta tttgtagctg ccatgattat tataccttga tttaccccaa
     8821 atccatccat ttcaactaga agttgattaa gagtttgctc tctttcatca tgacctccac
     8881 caagacctgc acctcttttt ctaccaactg catcaatttc atctatgaat atgatagctg
     8941 gagcactttt cttagcctgt tcaaataaat ctcttactct tgaagcacca accccaacaa
     9001 acatctcaac gaaatcagaa ccacttatac tgaaaaaggg aactcctgct tctcctgcaa
     9061 ctgctcttga tagatatgtt ttaccagttc caggaggtcc taccataagc attccttttg
     9121 gtattcttgc acccaattca atatatttct taggattctt taagaaatct actacctcct
     9181 gcaaatcttc tttttcctca tctagtccag ctacatcttt aaatgtaact ctagtttttt
     9241 catcatcttt atgaacctta gcttttgatt tgccaaaact cataaccttt ccgcctccac
     9301 cttgagactg attcataaac acaaaccaaa taatcaccat gaaaaatatt aacagtaatg
     9361 taggcaacat ttcgacaaac caaggtgtag atggcttagc ttcaccacca aaagttagtt
     9421 tcccagcctt agcttggtct aacacctcat ctgcaagttt atttcccatc acttctgttg
     9481 gaacatatga cttaaacttt gtatttgtat cttttatagt accttctaca gaagtttgat
     9541 ttacaaagta taatcttgat atattctcat ctgttaattc tctatatact tcagagaatt
     9601 ttaaatcttt tattttttct gtaggcttac ctgagaattg aactatacct actataatta
     9661 taaaaacaag tagataaaaa cctgcccctt ttagcaactt attcaatata gaagccctcc
     9721 tttcatacat tgctttgccc tataatttgt taaaattaat ttttaatact tcttttgtgt
     9781 tttcatcaat tttataattt tcactgattt tataatctcc aacacatatt attccttcac
     9841 tatctgtgat tataggaatt ttacatcttt cttctcttgg gatttttaaa tctatgaata
     9901 aatctttcac ttttttactt cccatagcaa gctttatctt atcaccttgc cttctgcttc
     9961 ttattactat accccctttt accttattaa aatcaaaccc tttagatgaa ttgtctaatt
    10021 tcatactctt atacctatct atgctcatta cttgggtctc aataatttgt tttaattctt
    10081 ttattttaat aaacccatta ctaggtacat tgtaataaaa ttcaatttcc tcattaacaa
    10141 tttcctcatt cgttaatatt atactgtctt tttttctata aacaaatata tttcttggaa
    10201 gagttaacat tttatttact tttgaattat cttctaaaga cattatatcc tctatatgtc
    10261 tttggtcaac aaaattagta tctcctagta tatgttttat ggaatttcta agaactctaa
    10321 ctttgatagc atcatgtaag caaacaaaat cgtctaaatt tatctctaca aagccttttt
    10381 cttttatatt tgaaacttct ctaaatttag cttctgcctc tttctcaata taatcgttat
    10441 cactttttaa actattgctc atcctcacta tagattctat tacatttgaa ttaaaattat
    10501 ccttcatata tggtaaaagg tctaacctta tcttatttct agtgtatata ttttctaaat
    10561 ttgttttatc tatcctcgga tttaaattat aagcttcaca atactcctct atctcatttc
    10621 tttccacgtc taatatgggt ctaattatgc aattatctct aatataatca attcccttta
    10681 agccttttaa acctgttcct ctcatgatac gcatcataac cgtttcggct tggtcattga
    10741 gattatgacc tattgctatt ttattggctt taatcttatc cttaatttca taaaacattt
    10801 catatcttag cttccttgct ccttcttcta atgataatcc ctcattttca caatattttg
    10861 gtacattaat agactttaca aagaatataa ttcccatatc ctcacaaagt ttagatacat
    10921 ataatgcatc tttttgagct tctatccctc ttatttgatg gtttaaatgt gctgcatata
    10981 tttctatatt aaaatctttt tttaatctat ttagtacatg caataaacaa actgaatcag
    11041 gtcctccaga aagacctaaa actattttat cgcctttttg tattaaatta tgtttattta
    11101 tagtacttag taccttatca aatatcatat ttatccctct tacacttagt tttattcact
    11161 tttaagtata ctttctataa aaaaacgcta aacccttgta tcaattttaa gaaattaaag
    11221 tttaatataa atataataat accaaataaa ttaaataaaa ggtagttttt tcactacctt
    11281 tataaaattt ctggaaaata gccatagtta ttatttagta cctatgtata tatctatttt
    11341 attcctacct aaaaataaat cttgtacctt tatattatag tctattttca attttatgtg
    11401 ttccccttct tgtatattta tatctaattc tcttgtatca atatcaatta ataaagtacc
    11461 ttgtggggtc acatactttg tagtactact ttctccacat ttaaacagca ttgttgagtt
    11521 aatagcacca aactttttga tactaacttg atttttaagt atctttatag tattagttat
    11581 ttctatattt tcttcttttt ccttgtaaat aacatatatt ccatcatttt tataaaaaat
    11641 tttaccaaag gcagtcatct ctatggtgtc catatttcct ttttcatcat attgtctagt
    11701 atttatactt atttttacac tcaacgattt ttcctccata gattcttcat ataaactagt
    11761 atttttgtat ttctactttt tgaatcttat caattttttt ctttaagaac tctcttgcta
    11821 tatctgaaaa tttttcaggt atatctgata cataatattg ataagttcca tgaatttctg
    11881 tattgtttat aatattttgc acctctaaaa tcttttttaa atcctttgca gtctctttag
    11941 ctggattaac aagttttata tgctctccaa cttcttcacc tattgttctc tttaaaatag
    12001 gataatgagt acatcctaac actaaagaat ctatattttt ttctttcaat tcttgtaaat
    12061 atatctttgc tgtcaattta gccacttctg tatttgccca tccttcttca acaataggta
    12121 caaataaagg acatgcttta ttaacaattt ctatactctc atctatttta gatatttcca
    12181 agttgtatgc ttttgaactt atagttcctt cagttcctat tattcctaca attttgtttt
    12241 ttgtagaact tacagctgtt ctagctcctg cttctataac tccaattatc ggtatatcat
    12301 atttttcttg agcttctttt aagcttcttg cagtagcagt gttacatgct ataactatag
    12361 cttttacacc ttttgttttt aaaaagttta tagcttgaaa agtatattta attatagttt
    12421 ctttggatct tgaaccatat ggtattctgg cagtatctcc aaagtatatt atatcctcat
    12481 ttggtaatat cttcattatc tcttttagaa ctgttaatcc acctaatccc gaatcaaaaa
    12541 ctcctattgg tttattgttc atctttatac aacacctact ttacattttt gtgtttaaca
    12601 acaacttatt tatcgctaaa atttatattt atattcataa ttaatatatt attacctaaa
    12661 tgattattat agtttatttt acacaaaaaa taaaggagct atcttaaatt agaaaataat
    12721 ttctacaaaa agacaactcc tttcactact taaaaattta aatttatttt gcaaacacat
    12781 gatttcctat tctcatataa ggattcaatc tatttatcca tttgcaagtg gctatttctg
    12841 gattccaaaa atatactgct ttattagttg ggtcagttcc ataaagagct tcctgagctg
    12901 ctttacgtgc tgagtctgtt ggtgccatct ttattgaacc atcaagcaca actgagaaag
    12961 catttttttg atatatgact tcttctattg tgtctggaaa tctagggtcc aatactctat
    13021 ttattactac agctgctaca gcaacctgtc cctcatagct ttctcctcta gcttctcctg
    13081 caaccaactt agataataac atcaaatcat tatcagataa atttattact tctttctttg
    13141 ctatattttt ttcttgtttg tttactttct taatattttc tgttggttca tatgcaaata
    13201 cctctttaat aggcataaat ataaaagtca aagctaatag tgtagccatc agtttactcc
    13261 acctgtccat gattaaaacc actccttaca ttcttatttt taaaattttt tctctaaatc
    13321 cttgactact tcaagtactt taaacttaat ttttactcta cttgtttttt ttggtgtatc
    13381 ttgttttatt aacttatatt ctttatcagt taaaacttcc ttcaacttat catctgtaga
    13441 tttatctatc actccattag attcatcaac aaaacatagt ggagggaaca taacacacca
    13501 ccagtttttt ccttcacctt tcccaatgat aatctttaat gctttatatt caccagctgg
    13561 aagaactata ttagaatatt gtttagtagg gaaattgcta tattgtatac ctacctttac
    13621 actgtaatta tatccatttt taagaataat atttttactt atttcttcca gactactata
    13681 ttcctttttt ataatagctt cactttcttt tatacttttt gaattttgaa gctttggctg
    13741 taaatatttt attacttcat ctctaacttt tagtttaagt tcttggtctt catctgtatt
    13801 gctgtttgct ataacatgaa atcttattaa tttatcttta taatcttttg atatattgtc
    13861 tacttttttt acctcaccat ttattactat tgtcattatt gatatgactg atataagact
    13921 taatattaat agtcccaatc taatcttaat ttttctcatt gaaaattccc cctcaagata
    13981 aatttatatc atcaattatg tccaattaaa tttaatttat tcataatatt ttttaatact
    14041 aataaaaaaa gctatcttaa aatgattaca atcattttaa aatagctttt taaaccttat
    14101 attttataag tctttactaa tcatagcctt atctatcata aactgctctg ctttttctat
    14161 atgctctgta gcatacttct tggatagctc actatcacct ttaattatag catcaagtaa
    14221 atatttatgc tcttcaacaa tattatgtga tgtatcataa gcagacatat aggtaactct
    14281 aaatctatat acttgttccc acaatgagtt tattaattgg attaattttt tattattagt
    14341 tgctttaaat atacattcat gaaattctac atcaagtttt aataacgcat ctacatcgga
    14401 ttccaaagtg ctttttttaa attcttctga tatatcttta agctttttaa tatcttcatc
    14461 actaattctt tcagcggcaa gatatgctgc taagccttct aggcttgctc ttacttctaa
    14521 tacatccata atatccttta atgacatatt tgccacatac gcaccttttc taggcaacat
    14581 aacgactaaa ccttctaatt caagctttct tattgcctct ctcactggag tcctacttac
    14641 tcctaattgt tctgctagtt gcacttccat tagcctttga ccaggcttta attttccttc
    14701 taagattgct tctcttaaat tctcaaagac tacatctctt aatggcttgt aattatccaa
    14761 gttcagttta gttaaattct ccacaaattt caaccccttt ttgactgcta ttaacaacat
    14821 acacctgttt atattttttt aataattctt tttttccaat tagagcatct tctttatttt
    14881 taaatagtcc aaaaactgta ggaccacttc cactcatcat agaacctaaa gcattatttt
    14941 tcatcattac ttgttttata tcacttattt ctttgtgttt acctatagta acattttcaa
    15001 gaatatttac catgctttct gatacagctt ttatatcttc agattttaaa cactctatca
    15061 aatatttatt atttggtctt tttttaatat tattcaaatc taatccttga taaacttctt
    15121 tagtagaaac gaataagtct ggtttgcata tcaatatatt tgtatcacat ggtaaacctt
    15181 tgatatttgt tagcttttct ccaatacctt gagctaaggc aggtcttcct gatatacaaa
    15241 aaggaacatc tgcgcccaaa ttaagtccta tttcttttaa ttcatcttca gataatctaa
    15301 gttcccatag gtgatttaaa cctactaata ctgcggctgc attagaactt cctccagcca
    15361 tccctgctgc tacaggaata tttttttcta tgaatatttc tacacctttt tttatataaa
    15421 atttattttt aagtattttg gcagctttat aaacaatatt atcttcatct aaaggaatat
    15481 ctaaactagt gctttttacc tttatttcat cttcgtctaa ttcttttatc tttactatat
    15541 cgtataaatc tatcgtttgc attatcattt caacaaaatg ataaccgtct tgcctttttc
    15601 ccaagacatc aatggataaa tttatttttg ctctactctt tagtcttata aaatccattc
    15661 tatcctcctt gtttaaagaa taatgcatca ctaacaataa tattatacta caaaaaataa
    15721 aataataggg tattataata ccctattata cttaattact ttaaattttt taatattaat
    15781 ctactaatac gacttttttt tctaaaataa gacacttacc aggcttaatt ggttcatcaa
    15841 gttttatatc attaagttct gcaatttcat tttctgttgt attgtatttt tttgctatat
    15901 tccagaaagt atctccttct ttgcatatat atacgattat gctaggagct ttagataaat
    15961 catatacacc ttggtcttct cccttgataa taaaattttc tgctttctta tctaatgctt
    16021 cagtaaatct cttaattttg ataatcaagt ctatctggtc cctattcaag tcaacttcga
    16081 ctttatcaat acatgctgta ttaaacacag atgctgtatc agttagatta tccatttcta
    16141 tatcatgttc aaatggaatt tcctcactaa ttttataaac caattttaaa ccttcaactg
    16201 ggacaaataa aatttcaact tttatgattc cttgtataat gcttttattt ccttcaatat
    16261 aactattttc tatagacatg gttggacaaa cgcttacaat atcttttatt tgtatatcat
    16321 cattatcatt tcttatgcct tctctaacca taaatgtttc ttcactacgt cttaaagtct
    16381 tatttaattg aataggtttg tggtcaaatt ttattatctt ttgaggcgaa tatgcatctt
    16441 gtaatacttc tcttgtaact tcatctgtaa cttttacctt acaacaagcc atacaatcta
    16501 tttctaaaag acctgtgttg ctttcactat tttgcttgaa aatatgatta aaatctgaca
    16561 tagacaacaa tacttcttca gtcataccat cactaactcc agggacttct acaaattgag
    16621 taaactcaat acctactcta tccaactcta caagttcacc ctcatatgta caagctaacg
    16681 gatttatttc taatactcca ccaataataa ctttattgtc agtcactcta ctttctttta
    16741 ctttaacaca tggatttaaa cttattatag attgaatttc ctctgtgttt attgttatag
    16801 tatctcttat agaactttct gctttttcta ttccaactat atcttgaaaa caaatttcct
    16861 ttctgtgctt ttgtatgcct tccacttgcg ccacatcttt tacaatgtct aacctttgct
    16921 tttcaaacaa acttcccctt atattcataa gagctcctac tttaatcttt ctctcattca
    16981 ttatagtaca atccatatgc tctacttctg aaaataacat gtattccata tcttgaataa
    17041 cattgtcttt ttctattact tcgtttatat ctacttttcc gtctacatta gaaatagtat
    17101 ttttatcatc tgcaatatag attacattat aattaaaact acctctgcaa agtatcttcc
    17161 catctgccat ttcaattttt ttaagtgata tgtatccttc tgtttttaca atttcatata
    17221 catctaattt tttgtctggt acaactgcct ccgcttcaat gaatgtttga aattttccaa
    17281 agtctattct attgtcaact ttaattacat ctttaattaa ttccatagtc tacctcctta
    17341 agtattataa aaatatcaca ctatatttat atttaaggag caaaaaaaaa attacaccta
    17401 tttttaaata ggtataattt taacttattt gtaatttatc ttgatctcta aaaacttgca
    17461 actttacatt agatgttaat aaatctgagt aactataaga tactctagga tatccattac
    17521 tttcatcatc taactttata acaaacacgc ttggataaac tttttctagt ataccctctt
    17581 ttgtaataat ctgctttctt cctttattag ctttcaacaa tattttcttt cctatatgtc
    17641 tctctaagct tactcttatc ttatctagag tttgaacagt agccacaata tcaccttctt
    17701 taacgtttat atgtttacat aatatcacat ataaacattt ttgtcaaatg tttaaactaa
    17761 ttattttata tattttttgc aaaaatgtca atactatttt tgaagatata cagtataatt
    17821 atgttaattt ttgctaatgt aatattgttt ttggcattgc ccatctaaat tttcctcttg
    17881 tttcagaacc accaattccc ttaacacctg taatagtctg ctctataacc tcatcaatag
    17941 gaactactac atcaattctt gaacaagcaa ttttctccac tataaaaaca gggtctaatg
    18001 catgtatcat tattcttcca ggcgaacttg catagtttgc tcctgcactt attatttttt
    18061 cataatttga ttggcatgct cctgcgaata tgacaagatt atccaaattt ggttgccatt
    18121 tacgtgcttc ttttactgtt ttaacaaaat ttgaagagtt tctatagtta ctcatatctt
    18181 ctatatctcc tctttttatt gtcattgcat catgacctgt tattactagt atatccggat
    18241 tatatttttc tagtagtgct cttacttctt tatactgatt ttgctctgaa acagctacac
    18301 ctactgcagg tattccaagt tgagcatata catccaagca aatttttaaa tattctttat
    18361 ctccatctat ctgtagtact tttccaggca ttccatatgt gttaggattt aattgaagtt
    18421 ttggaactgc tctagtcatt cttttttgtc tttctttagc ttttcttact gacttatata
    18481 ataaattttc tacattttta tctattaata tatcttttat atcaggtgct tttactaatt
    18541 ctaggtcatc aatataagca tctgctatta ctctaaatgc aattcccttt agtatagcta
    18601 ttttctcatt attttcatct acaccaaaag agactatttt aaatactata tctttgttat
    18661 gtgactttct agctacaatg tctcctacct tcatagttaa acctccaata aatttttatc
    18721 ttagtttata ctatgttcga tataaaactt tgtttcctaa tgtcaaaaaa acatttctta
    18781 taatacttct tttatcactc ttaaagcatt tttatagtat atcttttcta tatcatcttc
    18841 actaaaccct tcttttttta gaggttcata cagtttaccc atctgagata tatcttcaat
    18901 ctcaactttt gaatctattc catcaaaatc tgaccctaga gatacaacat ctattcctcc
    18961 aacatttaca atatgtttta tgtgtctaac catatcttca agtttacttt cacttttatc
    19021 acttaaaaat aagtggaaga agtttatacc tgtaactcca cctttatttg ctaatacttt
    19081 aatcatatca tcagttaaat ttctagaatg attcatcatt gctcttgaat tagaatgtgt
    19141 agcaattatt ggtttagaag aaatctttgc aatttcataa aatccaccat ctgaaatatg
    19201 agaaacatca accaacattc ccaattcatt catcttatgt accacttctc ttccaaaatc
    19261 agtaagccct ttttctctat attctacttt attatgagga aagctcaatt cattcacatg
    19321 attccaactt attgtcatca ttctaacccc taagtcgtaa aatttcttta aattttctaa
    19381 tttaccttca agtactgcac cttcttcaat agataaaaga gctgtaagtt taccttctga
    19441 ttggtttttc ataatttctt catagttagt agctaaagct atttcatcac tatttttttt
    19501 catttcctca tgaaatttat ttgccatact catgcaataa tcaaaaggat gttttacttc
    19561 ttcagtatca acaaaaagag caaatgtttg agctaatgaa tccccctttt tcaatctgtc
    19621 tatatcaaca gaatatttat tagacttaag ttcacttgtt tctacatttt ccattaattt
    19681 tgctatagta tcacaatgta aatcaataaa tttcatattt ataccccctg tatattttat
    19741 atttatatct aaaaatagaa atagttgtcc ttatagacaa ctattgacaa ctatttttta
    19801 atattctttt taatattact taatcttatt cttcttttaa gttaggtatt acttttttaa
    19861 cttcttcaat ttgatgccat gttttatcta tattattttc actaatatat ttttttaaat
    19921 cagttaaaga tgtaaaatct ttaactgata aattgtcatc atcatctgca aatcttaaaa
    19981 taaacatgag actcccttac tttccacaac atttcttata tttttttccg cttccacatg
    20041 ggcatgaatc atttcttcct atttttgctt ctttaactat tgttttagac ttcttataag
    20101 tctttattat ttcttttctt tggtctgctg gtagtatatc ttcccaacct tgtaaattat
    20161 atagccaatg agcctcaaca gttaccatat tgttatataa tttttcccaa tctattttta
    20221 tagaaacttc tttatcagct tctacttctt ctaaaactat atcttctttt aagctttcac
    20281 ttattccatc tatgaatccc atgaaaaatt cattagtagt tccaaatttt tcagccaatt
    20341 cacttacttt accttcaaca acatccattt tattatttaa tatttcattg tatattccag
    20401 cttcaacttt caaatattct tcccagaatt ttacttctgc ttcttgactt tcatgattat
    20461 cacttaaatt tctccattca gtatataaac tcatactttt tcctcctaag tatacctata
    20521 tttttatagt ttttatagta taaaatcttt tagttagatt ggaagtttct tctttttgat
    20581 tataccatat tctatttaaa gttaactctt atattatatc ataattaaac aattctttta
    20641 atacttttat agcatactct tggtttataa aataagggct tgtcgcaatt gttattactt
    20701 tggctttttt aattaagttt tttatcttgt aaaatttgag ttcaaatggt atatagtcca
    20761 tatcacttga aaatatatcc aaatctatgt caagaacaaa ctctgattct acttctaaat
    20821 caaatccata tagactatct attattatta attctgaaaa tatgttatat tttaaagcag
    20881 gttttataaa acttcccaca tttaaaactt catttgtata tctaaataca tcttttagat
    20941 tatttacatc tacatcatag ttctcaggtt ctctagtatc cttatgttgg tctacatgca
    21001 ctaacttgca tccttttgta aactcaccct ttaacaaaga ttttgcccaa aaataaaatg
    21061 catggttatg attgtcaaac acatatatct ttttatttcc caggacatat tcgaccatat
    21121 tctccaatcc ttttgctttt atttccttat tttcatctac ttcattaaat actacctcat
    21181 tgcctaacct tacatcattt aatgtaccat ttattagttt tggaacgtat atgctcttat
    21241 tttctctttt atcatatgaa aatacattat ttcctactgg tttttctata taaaatccac
    21301 tatattcata attttccata aaactttatt tcctccattg ttatataaat atataagtta
    21361 taattttaaa aattaaaatg cacttattgt aaatcatatc atctattata gaaaacatct
    21421 tatataacta aatataatat cttctctcaa tatgtattat acaataagtg caaaatatat
    21481 ttatataaaa tatactacat tcctataaca aaaccatcag cttcaattgg aaggtaacta
    21541 actcttctat tcaactccac ctttccaaaa aatactaccc aatatggtct aaaaatactt
    21601 tcaattttaa ctatttcaat ctctgggatt cctcccataa acctatgagt taatctcata
    21661 gccattttat ttgcctttgc ttttactctt cgttcgtcct tatcactata ctgcacaata
    21721 ttacaatcca cattttttac aacttcatat gtaggaaaat cttgtactat actaccagaa
    21781 cctgtagaac cattcactaa aatttttaat tcatttatat cattagaata tctcctattc
    21841 ttgaaaatgg atttcgtttt gtgaatttta agtgtgataa ttttaaactc tatataatga
    21901 agtctaactt catgagcata tttgttcttt aatattagct tactaaataa agaatttttt
    21961 ccacttttag ctatctctat agcttcttct tttgtaattc ttataggtaa cgctcttata
    22021 tccataaaat cattctcttt cttatttttt tcttgtcatt tttaaaactc tatatatata
    22081 atcaaaaaat attacaatta caactgccat aactccatat ggaattattt ttccaactat
    22141 aatatcattt ctagtcaata taccataaaa tataaatcct gttattaaaa agtacaataa
    22201 tactagaaaa ccgtctattc caagccattt tatttctaaa tcttttttta ccttagacac
    22261 taatttagac atagcagttt ctccttttat agattatttt gtgtatttaa attttcacct
    22321 attctattac caatcatcca tgcaataaat gaaaaaggta tagctatcac aagaggctct
    22381 aactcaaagc tctgaactgg aaatatttta aaataaccaa aagtcactcc accaacaatc
    22441 attcctaaaa taccacccat agatgttctt cttccatttc caagaagccc acctactata
    22501 ggtacaaatg ccgaacccat ccaaatactt cctacaaata tacatgcatc atatacattt
    22561 tcaaatctaa atgctacgct aagccccata actgctgcta aacatacacc tattctagta
    22621 aactttacta attgtttctg agataactct ttttttgtaa ttcttccata tatatcattt
    22681 gctaatgtag ccccagctgc tagataatag ctatccaatg ttgatattat agaacctaaa
    22741 attcctatta taaatattac tcttattcct tgtggtaatg tatctaaaac taaagttata
    22801 tatccagcag ctggagccat ttctggataa gtagctctta ctataagtcc tgtcatagtt
    22861 aacaccatgt caaaacatat ccatagtgaa aaacaagtta ataaggctct tcttccaacc
    22921 ttaggagaat ctgctgctga aaatctttga taaaaagttg ggtctgaata agctccaaaa
    22981 gaatatacaa ttaacatcaa tgctttcata gctgacatac cttttgtagg gtgcataagc
    23041 tgtggtgcat ctttgagtgc ttctgtaaga ccttgaaacc ctcctatttg ttcaaattga
    23101 cctggcataa ccatagttaa accaaatacc atacaaaaaa acaataccat atctgtaatg
    23161 gcaactccca taagcccacc aagtactgta agtacaacga ctactcctac cattattaat
    23221 cctattaatt ctttatctat tttccatgct acgttaccta tagttcccat agcagttatt
    23281 tctccaagtt gtgcacaata tataaacatc aaaattgccc caattatagc aacatgcttg
    23341 ccataaaaac tttccagtaa atcaggaact gttatattgg ttcttatatg aatccttgga
    23401 ccaacccaca atgctaaagg cattctccca atatgtgcag ctattgacca aactgcccat
    23461 gcagatattc catatatagc cgcatactct acactaccta ctgtaccaac tcctccatac
    23521 catgatgcaa ccaaagttcc tactattaag gaccatggta aacttcgatt tcctaggtaa
    23581 taactttcca tatcttttac atttctagaa aaataataac ctattcctaa taatataaat
    23641 gcaaatataa ctataatccc attttcccaa aatgttaaca tatctaatct ccacattctt
    23701 atattttaat ttttaacttt aatatctaaa tatgaacaac tctacccatt tccataaaaa
    23761 taggtagagt tatataataa ttataagtat ttaagtaatc ttgttattaa gcaattttat
    23821 tgtttaaacc tttattttcc cttttattta ttttatttaa agcataagta gcaaatatcc
    23881 ctataactgc acatactaca gataaaataa atatatatgt atatcctgtt tgtccatatt
    23941 tatctaacca attacctgca atagtgtaat aaaacgcatc tggagaaaat cctataaatg
    24001 aagcaaatcc aactactgct cctgtagttt ctaaagatat attagactct gaaacagatg
    24061 caaagtatat acctctaaat ccaaataaaa ttacacttag tattatcatg tttattacag
    24121 ctatccatat aaatcctgta ctcttaggaa taaccaagta agcagctgta cttactgtca
    24181 ttaatataaa tcctacaaac attactctta tagatgaacc aactttatct gttataacac
    24241 cagcaactgg agatgctccc atttttataa cataagttct tattattgat aaagcagaaa
    24301 ctagagtcat tggcattaca taaacttctg ataagtatgg acttaaataa gttaaacttg
    24361 agaatactaa ataagttgaa aatattataa gaccaattaa ccaagccttt ggcattgtaa
    24421 ctacttttaa caatgactta atacttaatc cttcatctga tgctccacta tcttttttct
    24481 cttctactaa gaaaaataga agtataccac atattataga tgctgcagaa tataaccata
    24541 ctacatattt gaatcctact gttatttcag caaatttacc aaagaaataa agacctataa
    24601 aagaaattaa tgtacctgat acgcctgata acccttcata aaaaccaaat attcttcctt
    24661 gctctgactc acttccttgc attctaacaa ccttaacaga ggctgagaag aaggttaata
    24721 ttgttgtaaa tccccataat acaaatatta aaagtatcat actatatgat gggaatgtag
    24781 agaaataaaa tccaagtatt cctgaagcaa ttaaagaaaa agttattaat tttctaaccg
    24841 agaatctatc tgcaaaccat cctcctataa aataagatac cattcctact aatccatata
    24901 aactcaataa gttccctatt tgtgtatggc tcaatgataa agcttgttgc attgggtcat
    24961 aaaatgatga tttcatatat ggtaaactat acatagccgt tgttccaaat gccaatatga
    25021 atattatcaa gaatctttta aaattacttt tgttctccat tgattttctc tccttaaaat
    25081 tttattagtt ataactttat tcatataatt ttattttaat ttttctattg cttgtttaaa
    25141 atcatttatt atatcatttg aagattctaa tcctacagct attcttatta gattttcccc
    25201 attcatttga actaatgtat gctcttcccc taagcttgtt gctattgttg caagctctaa
    25261 agaattcatt aatcttctac tagcttggtc tcttgtcaat ccattgatac catccttaag
    25321 tttaaatgaa actacacctc cacctaaacc attcatttga gttttacaaa gctcatattg
    25381 aggatgtgat tttaatgctg gatactttac caattccaca ttctcttctt cctctaaaaa
    25441 ctctgctact gctaatccat tttcacaatg ctttttcatc ctcatatcta acgttttcat
    25501 accccttaaa atcatccatg cactcattgg tggtaaagat gctcctgtaa aacaacataa
    25561 acttggccat ctaactaaat ctattaattc ttttgaacct gctactgctc cccctaaagt
    25621 atctccatgt ccatttataa acttagtaag actatgtatt actaaatctg cacctaaatc
    25681 tattggtctt tgtacaattg gtgtcccaaa agtactatca actatagcta agcttttatt
    25741 ttcatgagca atttctgcta ttgtttttat atctactaag tctaatgatg gatttaaagg
    25801 actttctata taaactattt tagtatttgg tctcattgct tcttttacat tttgtggatt
    25861 tactgcatct acaaatgtaa cttcaactcc aaatttagat aacagctcag acatgaataa
    25921 tttagtgtgt gaaaatattc catctgaact aactatatgg tcaccacttt ttaccaatgc
    25981 taatatagta gatgttattg cccccatccc tgatgtacta gatatggcac tttctgcatt
    26041 ttcaagcata gccaacttag cttctaactc tgtaagagta ggattacact ctcttgtata
    26101 cacatatccc catgtcatac acaactcttc aaaatgctct actgtctttg cagcaaatgt
    26161 tgctgtttga catattggtg tagccaatgc acctgttgtt gggtctgcac tatgtcccca
    26221 atgtattatt tttgtctcta aatcttgatt aatattgtta ctcattttga tttcctccca
    26281 ttttgactta tttatacaac gttttcccta ccaaatttca tcaatttagc ttagtcttaa
    26341 tacatttttt caagtatact tttttatttg ttataatttc taaaaatatg acacttattt
    26401 tgttttttta cagttctaat tataaactct atagtaacta tagagtcaat atgtttttga
    26461 tatttttttt acaatgttta aaatagtcag tacaaaaata ggtatatctt agaataacta
    26521 aagtcatcct aagatatacc tatttttata tcacaatata aataattaca tataagcatt
    26581 agttttttta tcataaatag atttttcaag atttatcatc ttttcataaa tatattatag
    26641 ttaaatattt taatattacc taacatctac aataaaatat actcttaaaa taaaattata
    26701 taattaaaaa tactctataa aagctaaaaa gtttttctat tcgctacatc taaaaataat
    26761 tagatagagg tataaatgta tttagtttat ttatacctct agtcttttat aaattatatc
    26821 tctactaaat tgatttttta gcacgaataa gtgtgctctt ggagatacca gtcatcttca
    26881 caacctctct atatggctta gaatttaata accccaatgc atattgtatc tgttgattgc
    26941 tgtatttctt tggcctacca tctttaaagt cctttttctt tttagcaaat tcttttccta
    27001 attgagtacg ttctattatc atatttctct caagttctgc aactgcaagt aatgtagtca
    27061 aaaagaattt acccattgaa gtattttcta aaaggcctat atttaaaata tgaacactta
    27121 cttctttagc aaataaacct tctattagtt gtattccttc tgatgtactt ctagctagtc
    27181 tatccagctt agttgcaaca agtaagtctc ccttttttag agatgatata attttttcaa
    27241 atttaggcct gtttgtagta gtgcctgtat aagtttcctt tattatttta gcatcattat
    27301 atttattcaa aatttcttgc tgttgctgat acaaactgtt gttgtctgtt tgattttttg
    27361 tacttacacg gcaatatcca tatataataa tcatcacttc ctaacataaa gattttgtac
    27421 agaagttacc cagaagcttg tttttactta tctttatcca ttttactaaa acgatttttg
    27481 ggtgtcaata ctgttaactt ttgacaccat aataattcct ttataatttg tttgactatg
    27541 tcaaaaatta ccaatataat gaaattaatg agtttataca aattggagga aataatatga
    27601 atagtctgtt aaaagaagca atagatgaat taaaaaacat ccattgcggg gaagtttttt
    27661 tattaaaaga attgttcaaa ggctatgaat ggaacaggtt ggagatgaat atcagattga
    27721 aattaggaaa actttttttg tatgaagtgg taactaatcc caatttaaat gtagaggtca
    27781 tcaataaaaa ttctgcttat cagcaaatgt ataaaaaaaa atagtgactt aaatgtatat
    27841 aatagtataa tcttcttatt gattcaaaag ttaaaacttt taatacaaaa caatcattct
    27901 attttaacat ttatcaatat gtctaaattt atataattaa cacatacgaa tagtattgtt
    27961 taaatcacat tatttaagat agataaatct taaccctact ccagcataaa tactaaaata
    28021 gggcttagaa ttatctatat ttttatccca taaaatgctt agctcttcct cttgattgaa
    28081 catatatatc tggggaaata caatagaagc gtaaatttat aaaatttcca aagtcagaaa
    28141 acttcagttc aaacttaggt ataccaaaac tttcaggtgc tatttcgtca acgccaaaat
    28201 agatgataat tccattatct gtaagataaa atgcttggtc ttcaggtata actaactcaa
    28261 cattagaata atacatttct ctattttcat ttatttgaga tttaatgtaa tcagtaatta
    28321 tattaatata atcaactcca tctctaaaaa tgtcattaag taaaagttct tttccagttg
    28381 tcaaatctat attgtaatta ttcaatgtat tgtatttagg cccatagtta ttagcaaacc
    28441 ccataaggtt taatatcata ctcagtacat aatttttatt aaaagtaact gcgtaactgg
    28501 tagataccca atagctttgt tttggaagtg aattttgaga agctgcgtta ttatattctc
    28561 gttcttcttc ctgtaagcca tttttaaaat tatttacagt cattcttaca gcattgttta
    28621 tgttatttaa aataactggg tttacatacg tggattgatt tctaatattg tatataacag
    28681 gatactttac atcatatgaa aaatacttac ttctttcaaa atcttcatta aattgtacat
    28741 ataatatatt atatgtacag gtatttgtag attgataatt ttccattaaa atcctccctc
    28801 ttttataaaa aaatcagata caatataata tgcttaaaac agtaataatg ttaatggtaa
    28861 atgtaaagaa tagaaagtat ctaaaacagc aaaaaatgac taattttgtg gtataataca
    28921 taggattgag agttatttta taggaggaaa aatatgttat tattagcaga taaatggaaa
    28981 gattatgaac ttatagatat gggaaatgga gaaaaattag aacgttgggg aagttatgta
    29041 cttagaagac cagacccaca ggttgtatgg ccaatggaat ctgaatgggc tttatggaaa
    29101 aaccctcatg gacattatca cagaagcaat aaaggtggag gtcaatggga acacaaaaaa
    29161 agatatccag aacaatggac tataaattat aaaaacttaa agtttcacat taaaccaact
    29221 ggctttaaac atactggatt attcccagag caagcagcta actgggattg gatgatagag
    29281 aaaataaaga aagctaacag acctataaaa gtgttgaatc tttttgcata tacaggtgga
    29341 gctactgtag catgtgcatc tgctggtgca gaagtatgtc atgttgatgc tgcaaaaggt
    29401 atggttaatt gggcaaaaga aaatatagaa ttatcaggtc ttaaaaatca aacagtaaga
    29461 tttatagtgg atgatgttgt aaagtttgtt gaaagagaaa taagaagagg taaaaaatat
    29521 gatgcaataa taatggaccc tccttcttat ggaagaggtc ctaaaggaga agtatggcaa
    29581 atagaagaaa agttatacag ttttgtagat ttatgtatgg gagttttatc agataaccct
    29641 ttatttttct taattaattc ttatacaaca ggattttctc caatagttct tgaaaatgta
    29701 ttgtctacaa caataggtaa aaagacaaat acaggagata tatacggtgg ggaattagga
    29761 ataccagctt ccagagatgg taagatactt ccttgtggta tatttggaag atgggagaaa
    29821 aaataatgat aaaagtcata tatgaagata accatttatt agttgtagaa aaaccagtta
    29881 acatattgtc tcaaggagat aatactaatg ataaagatat ggtaaatctt ttaaaagact
    29941 atattaaaaa aaagtataac aaacctggaa atgtatatat tggtttaata catagattgg
    30001 atagaccagt aggtggagtt atggtgtttg caaaaacatc aaaagcagca tctagattgt
    30061 ctgagcaggt aagaagtaag actttgaaaa aaacttatct agctgttgtt catggcaaga
    30121 taaaatctaa ctcagatata ctaaaagatt ttttatataa aaataaaaaa actaatatgg
    30181 taactgtagt gaaaaaaagc cataaagatg ccaaagaagc tgaacttaac tataatgtat
    30241 tagattttaa agaaaatcta agtttagttc aagttaattt aaagactggt cgttctcatc
    30301 aaataagagt tcaatttgca agcagaaaac atccattata cggagaccaa agatatggca
    30361 aagaaataaa taagattgga caacaaatat ctctttggtc caataagata gaaatttgcc
    30421 atcctactac aaaagaaaaa atggaattta catgtcatcc acctgacaaa tatccatgga
    30481 atatatttta aatctcaaat gaggtgatta tatgagtaaa aaattttcaa taggagaaat
    30541 gtctaaactt cataaaataa gcatacagac actaaggtac tatgaccaaa tagatttatt
    30601 taaacctgtt catgttgacc aagaaagcaa ttacagatat tactcaattg accaattttc
    30661 acaattagat attataaaat atttaaaata tttaggtatg cctttaaaag aaattaagtc
    30721 aaagcttgat gaaaataatg aagaaattct aaaattacta acaaataaaa ttaatatagt
    30781 ggatgaaaaa attaaagaat tagagcttat aaagaaggta ctaagcacaa agaaagaaac
    30841 tatggaaaaa ggtatgaaag tagatgaagt tggtaaaata gtgagaaaac atattccacg
    30901 aagaagtatc ttatctatag agtatgaaga aggattaagt agtgaagaaa ctatggaact
    30961 ttccagaaga caaatagcaa atatattaga agataatata tctgtgttct atggtggagt
    31021 aagtggactt gtatctatag ataaattttt aaaagaagat aaagttattt atgacaatag
    31081 ttttgttact gttgaaagag acttatttga tataaaatca caaaaacata taacagaaat
    31141 ttcatctggt gattttattt gtatgacata taaagggcct tacaaagaaa attataccgc
    31201 ttttaagaaa ctggttgatt atgttgaata taaaagaata cctattgaaa attatatata
    31261 tgaaatacct ataatagacc ctctgtctac aaacaacgaa gaggaacttc taacagaaat
    31321 tcaaatacaa gttaaaaaga gagaaattga cttaagatgt ctagtgtagt aatctagttt
    31381 acttacacat cttaatatag ttgtctatta tcaacatatg atttttctag atagtgattc
    31441 ctaacagtga gattttcaaa aaataggagg aaatatggct aatgctaatt ccctcctatt
    31501 tttaattaat ccatatcatt ttaattaagc catgtcatca cgaagtgcat caataatatt
    31561 ttcttttttt atcttattaa tagtatacaa cattgtaata aatactataa ataaaacact
    31621 aaatatacta attccaatac taaaccatgg aatcacaaaa tcaatatcat ctgtaaccat
    31681 tactttatga attagccatg aagaaattac tgctatagga agtccaaaga acaatgctct
    31741 catgccataa aaggcacact caaaattcat catcttttgg aaatcatgct cagacattcc
    31801 tacagagcga agcatggcaa gttctctacg acgtaactta atattagttg aaattgtatt
    31861 aaacacattg gcaatcgaaa tcagagaaat cataattatg aaagtataag caaaaacatt
    31921 ggcaataaaa atgtaattac ggttctcatc catcattcca tacatattgt acagattgta
    31981 ctcattcgta actccctcac tctcaataat ttgctccatt tctgcaactg actgagtagg
    32041 atttttcgat tgaaagctta aactttcaat tcctgtagaa acaccaggaa tctcaaactt
    32101 atctttggct gaataaggag ccaatactct gaagcttgct ttcttcacat ctgaacttct
    32161 gattcctgga ggagaatcag gtggcactac tttgacaaat gaaatattca cattttgtct
    32221 ctcaggtatc tccaacttgc cattagtttc aggagtgagg ctaacattca tagaagaact
    32281 gttgaaaata tcaataatat tattatcctt tgttaccata gaaacagcaa tcagttttgc
    32341 attttgtcca gtatattctt ctgctggtaa tccaagactt ttaataatat tcagataagt
    32401 tctatcatca agaaattgca tatctactgg taattcaagc atttcactca tagaatgtga
    32461 accctcatag ttcaaataat cgtctgtaag ctcacttact ttggcaacac atgaataggt
    32521 cataagtttc tgatacaaac cttcgtaaac accatttgca gtttttagct tatcgtaaag
    32581 cttcaacatt tcgttgtctt tcataccttg tgtagaaaaa ataatatcct ggtcagtaac
    32641 ctctgacctc tgatttgaca tctgttttag gtctgctact aaagcacttg tagatataaa
    32701 taaaactatg cttaaaacaa gcgacaatac aatacttcga taacgtttct tgtttctttt
    32761 aaagtttttc atagcaagaa ctccctcaag accataaact cgctgtgtta gttttgatgt
    32821 cttcacagat ttagattcaa tttttacctc atttgtctga cgaatacact ccatcactgg
    32881 tgtgttggca gcctttcttg ctggtatgta agcagaaatt aagattgtaa ccatacttac
    32941 cactgctgca acgatgattg cagggataga caatgttaat gtcaacggaa cgtttacata
    33001 gagaatattt gcaaagtttt tagctatgac agaaatcaca agtccaatac tgactatacc
    33061 gattgcaaca ccaattggta taccaatcgc accaatgcaa attccttcaa atagcaccga
    33121 atttcgtaac tgttttgctg tagctccaac agatgaaagt attccaaatt gatgtgttcg
    33181 ctcgttcaat gacatgttaa atgaattata tattagaaaa attgagccta gcatgattat
    33241 ggcaagcaca atgccaccaa ccgagtacaa aaacatattg aacaaattgt tatcagaaac
    33301 acctatgaag cgcaacacat tgtcattgaa aatggaagca tggtctttag tgctacttat
    33361 gtaagagcga atctgatgtg gatttttcaa tgtgacaaaa aggctaagac tgtcagtctt
    33421 gacttgttta tcttctttgg ttatcaaggt atatcctggt gcagaagatt cttcaaatac
    33481 gggctttcta cagataccca caactgtata agttttctta tcctgtggca caaaaacttc
    33541 actcccagca gtgtatgggt cactctgacc aagcttttca ttttcactca ttcgtttccc
    33601 tacatccaaa gaaatagtat cacctactgc aaatttgaca ccaccatctg tcgcaacttt
    33661 acttgaaaca agaatctctc tactattttc aggtaatctt ccagaaatta aagttatagg
    33721 caaagtatca aaagcttctt tgctaaatcc agcaataaaa agatatggtt tatctggatt
    33781 tctgttacct tcaagtgttg catagccaat attttcaaat gttgcagtat ttgcaacttc
    33841 atcattgact ctttgttcct gtacaaaaga agaatctaca tccaaaaact ggacatgcca
    33901 atcaccatat tttataatag ctccatttgt catatagttc atcaaagaaa ctccaaaggt
    33961 agtaactgct gtaatcatag cagctgacag aacaactcct ataattgtta caagagttcg
    34021 agtgcgattc tttttcaatc cttgcagagc aactttgtta aaaatgttca ttaacgattc
    34081 accttcctct catcacgcac tacttttcca tctgaaatac agataattct atctgcctgt
    34141 aaagcaatgt tttcatcatg tgtgacaata atgagagttt ggtgatattt actatggctc
    34201 tctttcagta actggataat ctcttgtcca tttttactgt ctaagctacc tgtaggctca
    34261 tcagcaagca taactgctgg tgcattcatc aatgcacgac caatggcaac acgttgctgt
    34321 tggccaccag aaagttgatt tggtaaatgt gtttttcgtt cttttaaacc aagcaattct
    34381 aacaagtcat ttaaccgttc ttgattgacc ttacgcttat ccataagtat aggcaatgtg
    34441 atattttcta ctacatttaa tgtgggtatc agattgtgaa actgataaat caatccaact
    34501 tgtcgcctac gaaaaatagc aagtttttca ttgctttggc catatacatc ttgcccctcc
    34561 agatatatct ttccacttgt tggtacgtct actcctgcaa tggaatgtag tagtgtagat
    34621 ttaccagaac cagaagaacc aatgattgca gtaaactctc ctttttcaat agtaagtgag
    34681 acatggtcaa gtgcagtaac cttattttca ttcttaccat aaaccttaca taaatcttca
    34741 atctttaaaa acgccattat ataagtctcc tttcatattt tataaatata tcataggact
    34801 ttcaacttac atttaagtga catttaaatg agagattcgt cactttggaa aacgaataac
    34861 aaatattgca ccaccttgtg ggtgattttg tgcagtaatt gttcctcctt gtctcataat
    34921 aatcgtctta caaagtgcca atcctattcc ataaccagct gtgtttgaat ttttcccacg
    34981 ataaaatctg ttaaatagac atggtaaatc ttctttttta aagcctgctc cgttgtcatg
    35041 aatagtaagt tgagtaaaca aaaagttgtc ctcacaaatg atatcaattt ttccattatc
    35101 acccacactc tccatgcagt ttttaaatat attttgaatt gcttctgaaa gccaatttaa
    35161 atcacccaaa atccttactc cttttggtat atcaatatgt aaagtgatat tgtgcagttc
    35221 catgggaatc aaaagttgat gaagtgcaga actaatcaaa ttattcacat caatttgttc
    35281 tttttgaaag actacaatac ctgcatctaa acgtgataat tttaaaaggg aagtaatcag
    35341 ccagtccatt cgtataagta attcctctgt ttctcgtatc aactcttttc tctcatcttc
    35401 atcagaagta ttctctaaca gtgacaaaat aagagttact gatgtaagag gagtgcgaag
    35461 ctggtgggct atgtcagcta gtgagtcagc aaggtgttct ttttcttttt tcagtgcgta
    35521 attttgctct ctaatacgta acgtcatttt agttatttca ctttgtagaa tagaaagctc
    35581 accctcatct gattcagcaa tatacagatg gttagcatta tgaagcacaa gattaatttg
    35641 ttctgaaatc tgtgcaatac ttttgtatcg atttttagta aacacaaaaa atgctattcc
    35701 aaaggtagtg gcagaaacaa tagaaagtat tccagtcata atactgattg caaatcccag
    35761 ggctacagtg agaatagtaa ttaataagaa taaaatagca aattttcgaa actctctatt
    35821 tcgaaacata acttcccccc aatctatacc ctgtcccacg aacagtcaaa attatttgtg
    35881 gacttgaagg gtcatcttct atcttctctc gcaagcgttt gatgtacaca gtcaatgtgt
    35941 tgtcattaac aaactcacct gccgcatccc acaattcatc aagtaatctt accctcgtaa
    36001 taatactttt aggattgcta ataaacacca ataacaaacg gtattctaaa gctgaaagaa
    36061 aaacctcatt gccattcttt ttcacaacac cggttgccgt atctacataa agcccacaaa
    36121 tttcaaaagt tgacccaaaa cgcccacttt ttcgtagtgc tgttctaatt cgcgcaatca
    36181 gttcacgtgg acgaaaaggt ttagtaatat aatcatctgc acccatattc agtccagtaa
    36241 caacacttga ttcatcaccg gaagctgtca aaaagataac aggaatgtct tgcttttctt
    36301 tgatttctgt gcaaatcgta aacccatttc catcaggtaa agaaatatca ataagtgcca
    36361 aatcaaattt attcttagca atctctacaa gtgcttcact tcttgtggat acatgggtta
    36421 ctataaatcc ttctgaatta agcaaaagaa taagattttt ggcaattgct ttatcatcct
    36481 caactaaaaa tatccgtttc atttactttc atcctccttt attttattag ttttatatat
    36541 tccagcagag caatagtaca ctactatttt acttatcatt acacaatttt cagtagtttc
    36601 ttttgttctt atataatcca tgcataatac ctccattgat ttattatatt tcttataaca
    36661 taaatacaca agataagaca aaaaacataa tgtaagtgca agttttttaa ctcactaact
    36721 tataaacata cactcctact aacactactt tcttgatgac acatcttaca agcttatatt
    36781 catacatcaa tgaaaaatta aatttatcca tttattaaaa taaaaggcaa tagcttctat
    36841 agctaatgcc ctttatctta aaatgattta aatactatac aatttttata aatggctata
    36901 aataaactcg tatagaatat aaaatttatc tacagtcttt tgttatacaa aatttataac
    36961 ctcttataga acaaatttac cactttgcaa acttatcact tttactcagc tatattataa
    37021 acttttaatt tatctttgtt taaatgtttc ttcttaactt ctactaaagc ttttagcgta
    37081 tccaaagatg tcattatttc agtagaaaat tcaatagctg ttcttcttat cttaaatcca
    37141 tctcttgtag agtcatttcc tttagttggt gtatttatta ctatatcaac ttgtttattt
    37201 cttatagcat ctaatatgtt tggtctagat tcttctactc tatttactat atcagcctct
    37261 attccatttt ctcttaaact cttcgctgtt ccttctgtag caacaaaagt atatcctaat
    37321 tctttcatat cttttgctat ctctataaac tcatctttat catgattatt tacagtagca
    37381 agtactactc ctctttcatc agacatatgt ctacctgctg ccaagaaccc tttatataag
    37441 gcttcttcta aattttctcc tacacctaga acttctcctg tagacttcat ttcaggtcct
    37501 agacttactt caactttaga taatttagac attgagaata ctggtacttt tactgatact
    37561 aattttggct ctttgtaaac tcctgtacta tatcctaaat cctttaattt agctcctaac
    37621 atacacttag tagccaagtc aactattggt actccactta ctttacttat atatggaact
    37681 gttctactag ctctagggtt aacctcaatt atatataatt cattttgaaa ttctataaat
    37741 tgtatattaa ccataccaag cacattaagg tctaaagcta tttttttagt gtattctact
    37801 attttttctt ttatttcatc agatatattt tgacttggat acattgttgt actatctcca
    37861 gagtgaactc cagctctttc taaatgctcc attataccag gtatcaatat atcttcttta
    37921 tcacatatag catctacttc tatttctcta ccagttagat atttatctat aagtactgga
    37981 tttttatggt ctctatcaaa tgcatcatcc aaatactgaa ttagtttttc ttcgttataa
    38041 gttatttcca taccttgacc accaagtaca taagatggtc taactaatac tggataacct
    38101 aactccttag caatttcaac accttcatta gttgtccata caccttttcc ttttggtcta
    38161 tttatatcta gtctctctag taaatcatca aatttttctc tatcttctgc tgcatctata
    38221 tctctaaagt ctgttcccag tataggtata tttttttcat gtaaaaactt agccaatttt
    38281 atagctgttt gtccaccaaa ctgtagtatt acaccttctg gtttttcttt ttctattata
    38341 tttaaaactt cttcttctgt taatggttca aaatacaact tatcagatgt atcaaaatcc
    38401 gtacttacag tttcagggtt attgtttaca attatagttt ctattcccat ttttcttaaa
    38461 gattttacac agtgaactga acaatagtca aattctattc cttgacctat tcttattgga
    38521 ccagaaccca atactacaac ttttctctta tcactaacta ctacctcatc atattgttca
    38581 taagttgaat agtaataagg tgatagagct tcaaattctc ctccacatgt atcaaccatt
    38641 ttataaactg gttgtatatt atataaactt ctcaattcat ataatttttc tgggcttatc
    38701 ttcattaagt cagatatacc tttatcagaa aatccctttt tctttaattc atgtaaatat
    38761 tctttatcta agtcttctat ttttagaact tttaactttt cttcttgttc tactatccat
    38821 ttaaatttat ttataaacca cttatcaaca ccagttattt ctgatatcat ttctacttta
    38881 tagcctcttc ttatcatttc agctaagtca aatagtctct catcatcagg tactactact
    38941 ctagccttta attcttctaa tgttctacct tctgatggag catgaaccaa tgaatatttt
    39001 cctgtttcaa gtgatcttat acctttaaga atagcagcct caaagttact tcctatactc
    39061 atgatttcac cagttgccat catcttagtt cctaattttc tattggcatg tctaaattta
    39121 tcaaatggcc actttggtat ttttactacc acataatcta atgttggctc aaaacaagca
    39181 taagtttttt tagttactgc attttctatc tcatccaaag tataacctaa agctatctta
    39241 gctgctactt ttgctattgg gtatcctgta gcttttgatg ctagggctga tgacctacta
    39301 actcttggat ttatttctat tatcgcatat tctaaactat gtgggtttaa agctatttga
    39361 acgttacatc caccttgaac ctctattgca tttattatgt ctattgatgc ctttctaagt
    39421 agttgatact cttcatcact tagagtttga cttggagcaa caactatact gtctcccgta
    39481 tgaactccaa ctgggtctac attttccata ttacatacag ttatacagtt tccatttcca
    39541 tccctcatta cttcgtattc tatttctttc caacctttta tactcttttc aagaagaact
    39601 tgtccaacag gacttagctg tagtccatgt gaaagtattt ctcttaattc ttcctcagta
    39661 tcagctatac ctccaccagt tccacctagc gtatatgctg gtcttacaac tactggatat
    39721 cctatcttat tggcaaactc aagacctgct tctaaatttg taactatatc actaactatt
    39781 actggttgat ttatttcttt cattacttct ctaaataaat ctctatcttc gccctttttt
    39841 atagattcta tagatgttcc tataactttt acattatatt tatctaatat accagcatca
    39901 tgtaattcta cagctaagtt taatcctgtc tgaccaccca tacctgcaag taaactatct
    39961 ggtttttctt tttctattat tttttctata aattctattg ttaatggttc tatatatatt
    40021 ttatctgcaa tttctttatc agtcattata gtagctgggt tactatttac taatacaact
    40081 tcaattccct cttcttttaa tgcttggcag gcctgtgttc ctgaatagtc aaactctgca
    40141 gcttgaccta ttattattgg ccctgaccct aatactaaag ttttctttat actatctaat
    40201 ttaggcataa ctctttctcc ttatctaaac aattttcaca gttcttatct tcatcatcta
    40261 tacaatcaac tttaattact ttattttatc ttaaattcaa atttactcat caatacatct
    40321 atttaataca tctatgttaa ttaaaccaaa ctttttgatt taagttattc ttgtttttta
    40381 gttagctatt ctaatgttat ttattttact aattctaaaa atttatcaaa aatatagtca
    40441 ttatcttttg gtcctgggca agcttcagga tggtattgaa cactgtatac atctagtttc
    40501 tcatgtctca ttccttcaac agtattatca tttaaattta tatgtgtcac tttcatttgt
    40561 tcaggaactt ctgaaacata ataaccatga ttttgagaag ttataaatac ttttccttct
    40621 tctaaatctt taactggatg atttccacct ctatgcccaa atttaagttt agcagttttt
    40681 cctccaagag ctaaagctaa aagttgatgt cctaagcata ttccaactat aggtttttta
    40741 ccaataagag cttttatatt ttctataaca tcttctaggt cttctgggtc tccaggtcca
    40801 tttgacaaga atattaagtc agggtttata ctcaatacat cttctggaga tgttgtagct
    40861 ggaaatattg ttatatcaca tccacgagct ataaatgatc ttaatatatt tctttttact
    40921 ccaaaatcca taacagccac ttttggacca tttcccttta tatgctctac ttcttttctt
    40981 gtaacagttc taactgcttc tgtatttgaa aacttatcca atttatgttt aacatcttct
    41041 aatttactgt cttctaatgt aattatacct ttcatggttc cattatttct aagtatctta
    41101 gtcaaagctc ttgtatctat tccttcaagt ccgataactt tattttgctt taaatattgg
    41161 tctatatcaa tttcacatct aaaattactt ggagaatcac ttttctccct tactatgaat
    41221 ccctttactt gaactttttc agactctgct gatgataaat ttataccata atttcctaca
    41281 agaggataag tcatagtaac tatttgacca tagtaagaag ggtctgttaa aacttcacca
    41341 tatcctatca tcgaagtatt aaatactact tctcctacac tttcttctaa atatccaaat
    41401 gcctttccta taaaaactgt tccatcttct aatattaacc ttgctttcat actacagtac
    41461 ctcctataat tctctttaga caaactaaag aacattaact aaatataagc ttttaaatat
    41521 ctatatctat ttttcacttt tacattctag ttttatactt atttacattt attttttatc
    41581 tttttctatt atactacaaa tttcttaaaa aaaagaagtt atctcaaaag taaaaactcc
    41641 tagaaaaaat aacctctttt ttttatttaa taattaaatt cttaaactat acaatcaact
    41701 taatttctat tcagctatat tgtaaacttt taactcatct ttatttaaat gtttcttctt
    41761 aacttctact aaagctttta gtgtatccaa agatgtcatt atttcagtag aaaattcaat
    41821 agctgttctt cttatcttaa atccatctct tgtagagtca tttcctttag ttggtgtatt
    41881 tattactata tcaacttgtt tatttcttat agcatctaat atgtttggtc tagattcttc
    41941 tactctattt actatatcag cctctattcc attttctctt aagctattag ctgttccttc
    42001 tgtagcaaca aaagtatatc ctaattcttt catatctttt gctatctcta taaactcatc
    42061 tttatcatga ttatttacag tagcaagtac tactcctctt tcatcagaca tatgtctacc
    42121 tgctgccaag aaccctttat ataaggcttc ttctaaattt tctcctacac ctaggacttc
    42181 tcctgtagac ttcatttcag gtcctagact tacttcaact ttagataatt tagacattga
    42241 gaatactggt acttttactg atactaattt tggctctttg taaactcctg taccatatcc
    42301 taaatccttt aatttagctc ctaacataca cttagtagcc aagtcaacta ttggtactcc
    42361 acttacttta cttatatacg gaactgttct actagctcta gggttaacct caattatata
    42421 taattcattt tgaaattcta taaactgtat attgaccata ccaagcacat taaggtctaa
    42481 agctattttt ttagtgtatt ctactatctt ttcttttatt tcatcagata tattttgact
    42541 tggatacatt gttgtactat ctccagagtg aactccagct ctttctaaat gttccattat
    42601 accaggtatc aatatatctt ccttatcaca tatagcatct acttctattt ctctaccagt
    42661 tagatattta tctataagta ctggattttt atggtctcta tcaaatgcat cttgtaggta
    42721 ttgagataat ttttcttcgt tataagttat ttccatacct tgaccaccaa gtacataaga
    42781 tggtctaact aatactggat aacctaactc attagcaact tcaatacctt cgttaagtga
    42841 ccatacaccc tttccttttg gtctatttat atctagtctc tctagtaaat catcaaattt
    42901 ttctctatct tctgctgcat ctatatcatc aaaatctgtt cccagtatag gtatattttt
    42961 ttcatgtaaa aacttagcca attttatagc tgtttgtcca ccaaactgta gtattacacc
    43021 ttctggcttt tctttttcta ttatacttaa aacttcttct tctgttaatg gttcaaaata
    43081 cagcttatct gatgtatcaa agtctgtact tacagtttca gggttattgt ttatgattat
    43141 agtttctatg tccatttttc ttaaagattt tacacagtga actgaacaat agtcaaattc
    43201 tataccttga cctattctta ttggaccaga acctaatact atcacctttt tcttatcact
    43261 aacaactacc tcatcatatt gctcataagt tgaataatag taaggagata tagcatctat
    43321 ctcacctgca caagtatcaa ccattttata tgctggtttt atattgtata gacttctcaa
    43381 ttcatataat ttttctggac ttatcttcat taggtcagat atacctttat cagagaatcc
    43441 ctttttcttt aattcaagaa gatagtcttt agttaaatct tcaattttca taacttttaa
    43501 tttttcttct tgctctacta tccatttaaa tttatttata aaccatttat ctatacctgt
    43561 aatttgttct atcatttcta ctttatagcc tcttcttatc atttcagcta aatcaaatag
    43621 tctctcatca tcaggtacta caactctttt ctttaattcc tcaatgcttc tctcctcaga
    43681 tggtgtgtga actaatgaat attttcctgt ttcaagtgat cttatccctt taagaatagc
    43741 agcctcaaaa ttacttccta tactcataat ttcaccagtt gccatcatct tagttcctaa
    43801 ttttctattt gcttttttaa atttatcaaa aggccatttt ggtatttttg ccaccacata
    43861 atctatagtt ggttcaaaac aagcataagt ttttttagtt actgcatttt ctatctcatc
    43921 taaagtataa cctaaagcta tttttgacga aactttagct attggatatc ctgtagcttt
    43981 tgatgctaaa gctgatgatc tactaactct tggatttatc tctataactg catattcaaa
    44041 actatgtgga ttaagtgcaa attgaacgtt acaaccacct tgaacttcta ctgcatttaa
    44101 tatatctaaa gatgcttttt taagcattgc acattctttg ttacttaaag tttgagttgg
    44161 agcaacaact atactgtctc ctgtatgaac tccgactggg tctatatttt ccatattaca
    44221 tacaactata caatttccct ttgaatctct tattacctca tattctattt ctttccaacc
    44281 ttttatactc ttttcaatta atacttgtcc aacaggactt aattgtagac catgtgaaag
    44341 tatttctctt aattcttcct cattatcagc tataccccca ccagttccac ctagtgtgta
    44401 tgctggtctt acaactactg gataaccaat tgtaagtgca taatcaagac ctgcttgtaa
    44461 atctgtaact atatcactaa ctattacagg ctgatttatt tctttcatta cttctctaaa
    44521 tatatctcta tcttcacctt ttttgataga ttctactgaa gtacctatta tctttactcc
    44581 atatttatct agtatgcctt tttcataaag ttcaactgct aggtttagcc ctgtttgtcc
    44641 acccatacct gcaagtaaac tgtctggtct ttctttttct attatttttt ctataaattc
    44701 tattgttaat ggttctatat atattttatc tgccacttct ttatcagtca ttatagtggc
    44761 tggattacta tttattaata caacttcaat cccttcctct ttcaaagact ggcaagcttg
    44821 tgttcctgaa tagtcaaact ctgcagcttg acctattatt attggtcctg accctaatac
    44881 taaagttttc tttatactat ctaatttagg cataaatttt tctccttatc taaatggttt
    44941 ttactatctg taaataatac taaatctata ttaatgctaa gaatttatta aatatacaat
    45001 ctaaatcttc ttttgttgtg tattctggaa tgtactgaac actatatatt ggtaattcct
    45061 tatgtctcat tccttctata gtattgtcat ttaaatttat gtgagttact tctgtatttt
    45121 ctggcatttc tgaaacatta tatccatgat tttgagaagt tataaatacc tttccagttt
    45181 ctaaacattt aactgggtga ttacctcctc tatgtccaaa tacaagcttt gaagtctttc
    45241 ctcctaatgc caatgctaaa atttgatgtc ctaaacctat tcctgtcaat ggctttttgc
    45301 ctattaattt ttttatattt tcaactatat catttatatc ctctggattt cctgggccat
    45361 tagataataa gattaagtca ggatttatat ttaaaatttc ttctactgta gtcattgctg
    45421 gtactatagt tatatcacag ttacaagcct taagagactc tagtacacta tttttaacac
    45481 caaagtctat aactacaact ttagctccag taccttttat attttcaatt tcttttcttg
    45541 taacattttt tactgaatct ttgttacaat gctcttctaa tttagactga acatcttgta
    45601 atgatacatt ttctaaagtt ataattcctc tcttagttcc attgtttcta ataattttag
    45661 ttaatgctct tgtatctatt ccttcaagtc ctattacctt attttgcttt agatatgtgt
    45721 ctatatccat ttcacatcta aaattatttg ggttatcact tttttctctt acaataagtc
    45781 cttttacttg caccttattt gattcaacat cttctaaatt tattccatag tttcctataa
    45841 gtggataagt catagtaact atttgtccat aataagttgc atctgtcaat agttctccat
    45901 acccagccat tgaagtatta aatacaactt ctccaatagc ttcctttaga tatccaaatg
    45961 cttttccttc aaatactgtt ccatcttcta aaattaattt ccccttcata taagctacct
    46021 cccaaatatt ttatctaagc attttctatt tcttttacaa tattaatagc tgattctctt
    46081 ggattttctg cttttgttat aggtcttcca acaactaaat aatgagcacc tttttttatt
    46141 gcatctgatg gagttacaac tcttttttgg tctccaacct ctgctgattt aggtcttatt
    46201 cctgggcaaa ctgttataaa atcagttcca catgcttcta ctattttatc tacttcttgc
    46261 gctgaacaaa caaccccatc tattcctgat tcttttgcca gtttagctct ctttatagct
    46321 aactcttctg ttgtcatatt acatcctatg tcctgtaaat cttggttgct taatgaagtt
    46381 aaaactgtta ctccaactac taatggcttt tctatattta atctttctgc ttcttcccta
    46441 gcaattagtg cacattgtct cattccttcc atatctgata catgtattgt cattaaccaa
    46501 acattatctc tcactgcagc tttcactgca cttttcatag tatttggtat atcatggaat
    46561 ttaaggtcta aaaatatttt tttccctttt tctttaagat aatctattgt tttacctttt
    46621 gtggcaacgt attgctctag ccctacctta aatatgtcta cactatcttc taatctgtct
    46681 attagttctt tagctttatc aaattcgtca gtatcaattg caactatcaa tttttcttta
    46741 ccatttatca tttttacatc tcctttttaa taaagcctaa ataatcataa aaaaatcctc
    46801 acaccaaaag aggcataagg attttatcta tacataactc tattcattag ctatgagata
    46861 tctttcccag tctctctgga ctagtttaaa agactttatt atatttaaat ttttatttta
    46921 tactcatcaa aaacctctag aagatttact agaggttata tactaacatt atctataacc
    46981 ctttagtctc tctggactac tttaaggaat ttagctgtaa tatttttctt tatttatata
    47041 actttatgta tctataggat aatttaaagt tttatctttt ttataattaa accactaatt
    47101 gctttttatg tcaataagtc tttgaattat tcttcatctt tatcaaacaa ttttttctca
    47161 aaatatgatt ctgcattata tattgcagca actggattat gcccagttac tctatctttg
    47221 acaactaaag ttgttatagg agcttccata tatttcatgg ctaaagtatc gtgaccaaca
    47281 cataatccaa gaattacatt aaggtcaacc ttagcttcat ttaaaaataa agcttgtcct
    47341 attggattgc acattacctc atctgaacac tttgatattg tttgagatgc ttctagtcca
    47401 attgtactct taggcattgc cccattttta catataacag aaaatacttc aaacccatga
    47461 tgttcaaata ttttttgcac tgtttgcatt tctcttttta gtccaataca aaatgctatg
    47521 ccaatctttt tataaccaca ctttttagca aactctataa tctcttttag tctagtatat
    47581 tgacaatacc cccctgcttc aactaatcca gcattataag ctatttttct attctcttct
    47641 tcttcataaa gttgctttgc tttttgttgt agttcaattt ctctagttgg acatatcttc
    47701 attaatttat ccatatttcc attagaacag cctctaagat tacattttcc acacttatac
    47761 atatccaata tccccttcca aaattttatt catcttgcga ttcttctttt tctagagtta
    47821 cattttcttc ttgggtttct tcttctggtt tcacatgctc gactacagtt ataaaatatg
    47881 attttcctat tttattcctt ataggaagtt tttcatatga aacatctatt ttatttttta
    47941 tacaagctat atcaaaatgt cttaaggcta cacctaagct aaccttattc atatcttcac
    48001 agtgtttctt aggtctcttt tcaaataaat gaagacctcg ttcatcctta tggaaatacc
    48061 acggttgaga attttttaca gatggagctc ttcttgtcaa ttctaagata tctttccact
    48121 ttctattcct atttatctta tttatcatat cttttactgg ctttctatca ggtctagcat
    48181 atctcgtcct aaacaactct tcattttttg ctggatatcc aaatgctatt attatataag
    48241 gattttctat tttgttttca tcatcttctt ctgtttttat tccagctaga taatctaaat
    48301 catcttcctc atcttcttca aaattcttat tcccaatatc tacaaattcc aagatatctt
    48361 ctctctttaa gtttccttcc aaccagcaag tagctattcc caatgttgta aggcgcaaaa
    48421 ctacaccttc tgtagcaaat cctatattct gtaaatagtc ctcacctttg tctgatgtaa
    48481 ctactatata atgaggtgcc tttactttac attccttacc catcaaaaaa tgtattatat
    48541 gacctctatc aacaacatgt gctttaatat ttaaatcttc atttaagtat tctaaatttt
    48601 tacaacttct ttttatttct tccatcaatg gcttttttat ctttttactg gaaaaatttc
    48661 ttacagattt tctataaaaa atggcttcat aaagctccat ttatgccctc ctaactgaaa
    48721 tcttctgacg tataaactct ataaatttat ataaatactt tatatttttt atagttttat
    48781 ttcctttttc ctcctgccct attttgaaat tcataagaat atctactcta gtttaatata
    48841 gcattcaaaa ggcttaaatt ctaccttatc aatgtctata cattagcata atttttttat
    48901 ttgattttct atgctaattt aaataacaac actagctatt acctttttaa ttaagctttg
    48961 ccagaaaaat tttttttcat ttataaatat ctatctcatt attatattat aagttttttt
    49021 cggtattctt gtatagcttt tcactaaaaa agtattttta tttctacttt aatattatta
    49081 tcaacaaaaa acatactgct taaataagtt tgttatcctc ataatctgtt ttaattaaaa
    49141 tattttttta tttctcaatc tataaagtat aaatattttg aatatgaccc aaaatctaag
    49201 taaagttata atattttata agttgttcaa tattaaaaac ataagtaatg ttataatact
    49261 ttataagtta ttcaatatta aaaatatagg aggataaata tgaatttaaa tagaaattta
    49321 gaaaaatacg ctgaattagc aataaaagtt ggagttaaca tacagccagg tcaaattcta
    49381 cttataaagt caccaataga atgtgctgat tttgcaagaa atgcacttaa agaagcatat
    49441 aaatgtggtg ctaaaaatgt ttatatagag tggtctgatg aagaaagtac tcttattaaa
    49501 tacttatatg ctccagatga agcatttcat gagttcccca aatggacagc agaacaatat
    49561 gtagatatag caaaagaagg tggggcattt ttatcagtct atgcccaaaa tccagattta
    49621 ttaaaagatg ttgaccctga aagagttgca aattttcaga aggcatctgg aaaagcttta
    49681 aaagaatggc gttcttacac tctaactgat aaatgtaaat ggagtatagt ctctgtgcca
    49741 acaaaagatt gggcaaaaaa agtgtttcca aatttatcag aagataaagc aatagaaaaa
    49801 ctgtgggatg ctatatttaa atgttcaaga gtagatggtc aggaccctat aaaagcatgg
    49861 gaagaacata atgaaaatct taaatctaaa atggactttc taaataaaaa taactttaaa
    49921 actttaaaat ataaatcctc aaaaactgat ttgactctag acttgccaaa gggtcatgtt
    49981 tggctaagtg gagcatccaa agaccctaat ggaataagtt ttaatccgaa tattccaact
    50041 gaagagattt ttggaatgcc acataagttt aaagtaaatg gaactgttta tagtacaaaa
    50101 cctcttgttt atggtggaaa cataattgac aatttcttct taacatttaa agatggtaaa
    50161 ataatagatt tctctgctga aaagggacta gatacactag aaaaacttat tgaaacggat
    50221 gaaggctctc attatttagg agaagttgct cttgttccat acaactcacc aatatccaat
    50281 acggatataa ttttttataa tactctatat gatgaaaatg cttcttgcca ctttgcaatt
    50341 ggttctgctt ataagacttg tctggaaggt ggaaataatt taaaagatga agaattggat
    50401 gaacatggtg taaatgacag tttaacacat gtagatttta tgattggttc tgctgatatg
    50461 gatattattg gtgagactta tgatggaaag caaatacaga tttttaaaaa tggtaattgg
    50521 gctttttaac atatgatttt aactaaaaag ggctgatgga agttatacca gacttcccag
    50581 ccctttttaa tgttgatgat aaatattttt tatattaatt aatctcatta ttatagatta
    50641 attcctattg ttttaaacat aagtatctaa aacttatatt tatattatat ataaaatatc
    50701 ctatttagta aaacctttat tttaatttat atgctaaaaa tttaactttg ctatttcaac
    50761 agcagacttt gcatcctttg aataataatc agcacccatt tcttcagcgt attcttctgt
    50821 caaaactgca cctcctacaa atacctttgc atttatctca ttatctctca gtgcctgaat
    50881 tgtatctttc atactttgaa cagtcgtagt cataagtgca cttaatccta ctaattttat
    50941 atttctcttt ttagcaactt ccactacttc ttcaataggg acatctttac ctaaatctat
    51001 aacttcatat ccataatttt ctagcattat ttttactata tttttcccaa tatcatggat
    51061 atcacctttt actgtagcaa ctattatttt tcctttggat acattattgc tacttttact
    51121 taataaagtt tcctttattg tatttaatga aacttttacc gtttctgctg attgaatcaa
    51181 ttgtggtaaa aatatatctc cactatcata tctttttcct actttatcaa gagcaggaat
    51241 taaaatctca tctaatatat aattttcatc cttctctttt aaaagattca gtgttacatt
    51301 ttttgcttca tcttttaatc ctctttcaac taaaatatcc aagggcaaat ctttatcaat
    51361 ctttgtagat gaatccgatt tttttgaatt atttatattg ctatattgat ttatatagtt
    51421 tatacatcct ttatctgtgt tatttaatat tttaaaagaa ttgatagctt ccatcatact
    51481 atattcattt ggatttataa ttgctaaatc aagccctgcc cctaaagcta atgttagaaa
    51541 agaagcatta agtgctttcc tatttggaag accaaatgaa atatttgaaa cacctaatat
    51601 agtttttact cctagtgtct ttaccattgt tatagctttt atagtttcta ttgcttcttc
    51661 ttgttgtgct gaaacagtta atgataaaca gtctataaat atatcttttg gttttatccc
    51721 ataagaaact gctctattaa ctatcctttt tgctatttca aatctttctt cagccttttt
    51781 aggtatcccc ttttcatcaa gtgtaagtcc aaccacacat gaaccatact ttttaactat
    51841 tggtaatata ctttctaaag actcctcttt gccatttaca gagtttacta ttgttctacc
    51901 attataatat ctaagtcctt gctctaaggc ctctacattg gaagaatcaa cttgtaaagg
    51961 tgtatctact actgcttgaa tctctcttat taattttggc attagttttt tttcatcaat
    52021 ctctggaaga ccaacattta ctccaagtat ttgtgctcca gcatttactt gttctaaacc
    52081 taaatttata gcataatcaa cattttcatt ttttaatgct tcttgtagag attttctacc
    52141 tgtgggattc aatctttctc caacaactgt aggcgattgt acttccacaa attttgatgg
    52201 tgaacagact acacatttat caattttctc gatacatccc tttgtaacag aatttatatt
    52261 ctcagatatt tcttttataa aacttggatt cgtaccacaa catccaccta ttatagtagc
    52321 accaacttca acgaactttt taaccccttc aaaaaattct tttgcatcaa catcatatat
    52381 agcctctcca tcaactatat ttggaagacc tgcatttgct tgaaccataa cagggactgt
    52441 agctcttgat gctatttttt caactattgg taaaagttgt ttaggtccta atgaacaatt
    52501 aactcctatt gcatctacac ctagaccttc tatagtagcc accatacatt ctggcataca
    52561 tccagtaaaa cttcttccac cttcatcaaa tgtcatagta cagaaaatag gtaaatcaga
    52621 gttttctttt gctgctaata cagctacttt agcttcatat aaatccatca tagtctctat
    52681 tactattaca tcaactccag atttaacgcc ttgtagtact tgtcttttaa atatttcata
    52741 tgctttatca aaacttaaag tacccatagg ctctagcatt tctcctatag gaccaatatc
    52801 taaagctaca tatcttggtt tagtattatc tacattttct atagcttttc tagccaccaa
    52861 aacagcattg tcaatcactt cttctacagt atacttacta tctaatttta gttcattaca
    52921 tccaaaagta tttgtaagaa ttacattcga acctgcctct aagtatgctg tatgtatttc
    52981 tataagttta tctggatttt gaagaccaaa tacttctgga ttttcaccta actttaaccc
    53041 tttttgttga agcattgttc ccattgcacc atcaaatatt aatatattat ttttcagata
    53101 ttgtcttatt tccacaagag ttcgctcctt ttctatatgt acagtttcta tagtttttac
    53161 aattttcaca cgacttttct ttcttagatt tatttattct tgtattagaa atacctataa
    53221 tagccactac tgactttctc ggtatcataa ttccattaga agtaattgtt agacctattt
    53281 gtttttgagc attcaaaacg tttaatatat ctatattttt ttctattggt aaatctccat
    53341 atcctgggct atatcgcata gttataaatt tatcttgctt taaaaaaacc ttttctaaat
    53401 tattttgaac aatgtcacac acttcttcta ttgctgttgt tccacatgaa tcaattatta
    53461 gtccttttgt taaatttgaa taagagtgtc gtcttatttc tttttctata tctatcccta
    53521 tagtagctgc cataattaca cactcattac attcttttaa aagttcatat acatctttac
    53581 tctctaatgt taaatttgtt ccctctaatt ctacaacatt atctttattt attttaatag
    53641 gataaatcct agataaatat ctaggattta ttttattttt agttatagct acacattcat
    53701 caatagtata tttaaggtct ttatctatct cttgacctct atattgtaaa tatcttaaaa
    53761 cttcactttg atttatgctt atatcttctc ttccaattaa attattctcc atatatattt
    53821 aaagaaaatc ctttatctaa aacatctttt gcatattcct ttgccccaaa taaagataag
    53881 tctctgtagt ttccacattc tatagctgta gctgctggca ttttatctga ttcaagaact
    53941 ttttttaatg cttcttctaa accaatctta actgttttgg catctacatc tccccatagt
    54001 attaaataaa atcctgttct acatcccatt ggagataagt ctattacacc atctaatgta
    54061 tctcttaaat aagtagctaa aagatgctct aaaccgtgca tagcagcagt tccaaaactt
    54121 tctacatttg gctgtaaaaa tctcaagtca aatttagtta ctttatctcc ctttactcca
    54181 tcaagtacac tacactttct tacaaaagga gcttttactt ttgtatggtc tagcttaaaa
    54241 ctttctactt tttccattat ttaatcctcc attatacttt aaaatttgtt acattaattc
    54301 taaaaaaaac tcttcctatc tattattgat aagaagagta tattatttca agtcatctca
    54361 tcgttgttag caggaccacc tgataaaagg ttggtatagg atcactgagc taactctctc
    54421 ccctaactct tgataagtat cttattaaac tgacttaaat tatatattac ttttttattt
    54481 ttgtaaacac tttattgtta taatatttat atcacataat cgtactttta ttttataact
    54541 aagctgattg tattattggc agttgtactt caaacacagt ttgatattta tcgcttgaaa
    54601 cagtaatttc tccatcatgt aaatttacaa tattttttgt aatcgcaaga cccaatccag
    54661 aacctccaac atttctattt ctcgattttt caactctata aaatctatca aatatatttg
    54721 gtaaatctaa cactggaatt ggttccccat aatttatcac ttttacaacc gccatatctt
    54781 cctttttctc tgtgactata tctacataat gcccatcttt tccatatttc acagcattag
    54841 ttataagatt ttcaaatgct cttaccaatt tatttggatc agcttttaca attaattttt
    54901 cttcattaaa attaattcta ctaaccataa attcttgttt aaaataaatt tcaaattgag
    54961 atactacttg acttaataac tctactaaat ttatttctat tttgtttaat tttattgtat
    55021 tattttgcat tttagtcaat tcaaacaaat catttataag aacatttaaa tttttcgatt
    55081 tttcatatgc aatatcaaca taatacatca tctgaacttc atctttatac ttaccttctt
    55141 ctatcactcc taaataaccc attatggatg tcaaaggtgt tcttaagtca tgtgacacat
    55201 ttgttattaa atctgttttt gtctgctgag cttgtctctc ttcaatagtt atatttctaa
    55261 gttgatggac tatattattg attttatgtg ctagttcatc aatatcatcc ttttctttat
    55321 cctttaatat atctaaatca tactcaatat ctatactttt ttctaagtta ccttcatcca
    55381 ttaaatttac agcactttta atgatttcta atttttgatt ttttctatta gtctttctta
    55441 taaaatctac aatttgctta tttctcttgt acgatatcat ggaataaatt gctaatgatg
    55501 tgattgtaaa taaaaatgga taaaataaat cataccctat aagacttctg aaatctcttg
    55561 cttgatatac aagttgatta actacagaca tatcactatt gacatataat gattttatta
    55621 tatacatact tgttaaaata agcattgaag ttaaagcaca gcttattata agatctaata
    55681 tgggtcgaaa catatgattt aataaacttt tatttttcaa ttttatatcc tactccccat
    55741 acagtatgaa ttattttttc tccatctgta tatttttcaa ttttatccct tattctgctc
    55801 atatgaacca ttacagtatt attagattgg taatatttct ctttccatac cttttcaaat
    55861 atttcttctg tactatatac tctgccttta ttatttgcta gtaaatataa tatatcaaat
    55921 tctcttgatg tcaaaattat ttcatttcca gccactgtta cactatgttt ttccttatct
    55981 ataattacta ctccaacctt tatgacatct ttatcttcat tattagcacc actaaaataa
    56041 tatgctcttc taatcagcga cttcactctc acagtaagtt caagtgggtt aaatggtttt
    56101 gtcaaataat catctgcacc agtcattatc ccttgtattt tatccatgtc ttctgatttt
    56161 gcacttaaca taagtattgg tatattcaaa ctttctctaa cttttctaca aacttctatc
    56221 ccatccattt taggcatcat tatatccaat atcattaaat gaatattttc cttttttaaa
    56281 atatctagag cctcttttcc atcttcagct ttaattacat tatatccact atttaaaaga
    56341 tatatctcta taaggtctct tatttccttt tcatcatcca caacaagaac tgtattattc
    56401 atttttacac atcctaactt aatctttgta tatagcttta ttcatataaa attatactat
    56461 attttagtta gtgtaatcta taaatttatt aatttctaaa tttccaatat aatacaaatt
    56521 atttacacat ttatattatt tattttgtaa atattcttct aaagttaatc cttttgaata
    56581 aatttcctcg gcagcatcct taccaacata tctaatatgc catggttcat atgctgtacc
    56641 tgttatatct tctttacctt caggatatct tattataaat ccaaacttgt gagcattttc
    56701 tgccaaccat ttagcttctt ttgtacttcc aacaaaccat ctttctggat ttgttaaatc
    56761 aatacaaagt ccagtttggt gctcactgta accaggcttt gctacatacg catctgcctt
    56821 ttctcgcccc tgagatttta cccttcttgt ataagtatcc agttgagtat cataagatct
    56881 gtatgctgaa gaccctaaaa actgtattcc ttctgaatta gcttgcttaa ctaaatcttc
    56941 aactgccttt gcaggttctc ctgccatttg tttttcttcc tctgttgctt cttcaacaaa
    57001 aggtatgttt accttagtaa tattttcagg agtatagttt ttgctaattc catttgtctt
    57061 gtttaccaat aatatatttg atatactatt tgagtgattt ttattttgag aatttgcctc
    57121 aacatcttgt tctgaatcat gttgagcagc tactattgga tctttatctt tcttaagtaa
    57181 tctatcttta gatataaata cacttataaa tactactaaa ataatggctc ctattaattt
    57241 aaattttttc ataattaaat cttctccttt ttgttatgtt tgctataatg ttaattttag
    57301 agtataagac ttaagtattt tataagtaaa tcttaaataa atcttaaatt taatattttt
    57361 aaaggatggt gataaaatgt ctatacaaaa acttctaagt aaagctcgta aggctataca
    57421 agattttgat atgatacaag aaaatgataa aattgcggtt ggactttctg gtggaaaaga
    57481 tagtttaact ctacttcata tacttaaaag ttatcaaaga ttttctccac aaaactttga
    57541 attgatagcc ataacattaa atactggagg tgttgataat tctccactag ataaattgtg
    57601 taaagaaata aatgttcctt tttatgaatt tcaaactgac ataaaagaaa ttgtatttga
    57661 tataagacaa gaaaagaatc cttgtgcatt gtgtgctaat ttaagaagag gtgctttgaa
    57721 cgataatgct aaaaaacttg gatgtaataa agtagctctt ggtcatcata aagatgatgc
    57781 aattgagaca tttttaatgt ctatgtttta tgagggtaga gtaaattgtt tttccccaaa
    57841 gacataccta gacagacagg atttaacagt tataagacct atggtttaca tagaagagta
    57901 tatgactaag aaaatttcaa aagattctaa ctatcctatt atcacaaatc cctgccctgc
    57961 aaatggtcat actaggagag agtacataaa aaatcttatt gctaatttaa ataaagagat
    58021 gcctgatttt aaaagaaatg tatttggtgc tttaaataat tctgagaaat tgtttatatg
    58081 ggataaagag aagataaaaa attttaaata ataattaaaa tttttaaata aaaaagcaag
    58141 attgtattaa ttgtaaataa tctttatata atctacacaa tcttactttt ttatttatta
    58201 tatgttatta tctttaatct atattttaat agttcttaat agtatttatt ttgtctaata
    58261 cattaattat aacttaaata ttttatatat taatttaatc tattaattca ttcaatctac
    58321 tggtttaatc catttttaca gtatatacat ctacatatta taaaaagcaa aattatattt
    58381 tctaaatatt ttatgttaga ttataatatt aaattctatt atctctggta tattaaaaaa
    58441 tctaaatggt aactttgtac ttccaagacc cgaactcaca tataaatgat ttccatttat
    58501 gtcataaaac cctttagtat atttccttcc atatggagga gtaactaatg ctcccttaat
    58561 aggtaatctt atttgaccac catgactatg cccagataga actaaattca ttgtatcttt
    58621 actaagcata tctactaaat ctggttcatg tgctaacaat aaattaaaac ttttattatc
    58681 tatttgactc tccagatatt ttatattagg atttccattt aatatttcat caacacctaa
    58741 tatattaata tatttatcat cttttaattt tattttttta ttttcattta ctaaaagatt
    58801 gaagttggaa tttttcataa tctgcctata atacctagga agtttataca tataatcatg
    58861 attgccaaat actgaaaatt ttcccaacct agcattcata cttgataaaa tagttgtaat
    58921 ttcatctaca cttggatttt tattggagta atcaattaaa tcaccagtaa atactattat
    58981 atctggattc aaagtgttaa tcttattagc tacttttttg agattcttag ttgaataaaa
    59041 actacctatt tgagtatctg aaatttgaac tacttttaca ctttcagatt tactctcaat
    59101 tgaatcattt tttatcaatg ctccattttc acttatatta tattttttca caattaatag
    59161 actcggctct atcgcaactg agtatataaa aatcaaaata aatattaaga taaaaaattt
    59221 taaaaaatac ttaatttttg agttcaaaat atctacctac ttatttattt ttttaaacta
    59281 tttgcattac agactcaact ttgttcattt ttctgtcatg catttttggc ttatttgctg
    59341 aaaaccattt atatgttgct gtaagacctt cttttagtaa cacgtttggt atataaagcc
    59401 catgttcaat aagcttattt atatcaagat taaagtctat atttctaaat gggaaatacg
    59461 ttctttctct aaactctact ttttccatat ctacatattt tattataggt tctttgccaa
    59521 taatttctcc acatgtatat ataaggtcat cccaagaaat taactgtgga tttgtcacat
    59581 tataggcctc tcttacatga ggatttttca ttatgctttc caataccttt accaaatccc
    59641 caatatatat aaattgatta ctaacttgtt ttccttttgg tactggtatc ttttcatttt
    59701 tttctatttt ttcaaagaaa taatactctc tatataaatt attattttca ccatatatgt
    59761 aagttggtct aataattata tatggtatag ggctatttat aataaaatct tcagcctctt
    59821 ttttatttaa cccatatttt ccccagtttt cattttcacc tttctcattt tcttctttta
    59881 tatttcttcc actatcttta tatactgctc ctgctgacaa tactatatac ttttttaagt
    59941 tatccatgct tataaaatca atcagattac ttacatcttc ttttgtatat gctgtcatat
    60001 catatatgta atcatatttt cttcctgtga taatgttttc catatctttt cgaacttttc
    60061 tatcacaaat tagatgttct ttaaaaccat tataatctat ttccttttta ccatttgtaa
    60121 gtatatcaat ttgataccca catttaatca agcgcttagc aagtgcagaa cctatgaagt
    60181 cgcttccacc cataattaaa atagatttca ttttaagtgc atcctcctct tttttaaatg
    60241 acttccttaa ctataatatc atatttttaa atatgcgaca ccattttgta atatttttgt
    60301 ctataaaaga tatttataac aaaatatctt ttatagactc tacattttcg acaatataag
    60361 taggttcact ttcactaatc tcttcaaaag aaccataccc atacaatact ccaatagaat
    60421 ctatacctat ttttttagct ccaattatgt catactttct atctccaacc ataataactt
    60481 tatctttatc ttttacatta cataggtcta gtacatattg tataacttca tttttattca
    60541 ctcttgtacc atcaagattg ctacctgcta tatatttaaa atatctatct atatcaaaat
    60601 atctaagtat agtttctgca aaaactgttg gcttagaagt tgctactaat aatattttac
    60661 catttttata gagcatttct aatatctctt tcatattctc ataaatttta ttttcaaata
    60721 tccctttatc agcaaaatat tctctatact tttcaacagc ttctttagct tttttatctt
    60781 caaatttata atactccttg aaagtatcat gtaatggtgg tcctataaat tggtctaagt
    60841 tttccaaatc ttcttttatg ccaaagctat ttaaagaata ctgaatagac tttgttattc
    60901 cttctttagg gtctgtaagt gttccatcta aatcgaataa tactatttca taattttttt
    60961 tcatatttca gtcctccata tttgtaaaaa gtaatatctt atatattaag tttatctatt
    61021 ttaaaaagct atagtaatag aaatttctaa tactatagct taagtaccaa ttaaatctta
    61081 tatatttatt ttaaaaataa atttaaacag ctctatttaa ctgttatagc tgaaactgga
    61141 catccttctt cggcttcttt acataaatct tgtaaatctg ctggtatttc tccttcaatt
    61201 gctactgaat gcccttcatc gctcatacta aaaacgtctg gacatgttcc tatacatgct
    61261 ccacaagcta cacatacatc cttatcaaca aatgctttca tactaaaata cctcccctaa
    61321 aattattatt ttttaattgt tgtttcctta gatatttatc caatatatac caatttaaac
    61381 atatatttat tattttatca ctattgttta gtttattata gtattttcgt atccatgtct
    61441 ataaacttca ctgcttttca tccatgattt tacagtatat tgcaatctta attttttatt
    61501 taaaacaagt tcattattat tgtagtcttt tataatatca ttacactcct ccattgtaaa
    61561 tattgtaaaa tcaccttctc caccaatctt tattctgcct ttatttccat gtaaatcgaa
    61621 aatctttgtt gggtattcag ttactttttc tatacacttt tctagggata tcccaagttc
    61681 cataatttta tttataacat ttaaaagaga atagtttacg tctttcatgt tttttatatg
    61741 catatcagta cttattaggt caggctctaa accttgcttt attgcttttt taaaaacttt
    61801 aaaatcaaat tggtccactc catgacatac atcaaacaat actcctctat tctttgcatt
    61861 tattactgat tttcttaatg tgccagattc tttaaggatt ccatttgtac tatttccata
    61921 taccggtgta accacatctc cttttcccaa aatattcatt acttcatcta tatatgatgg
    61981 atactctcct atatatacca ctaagggtaa atttaatttt ttagcaactt gctttgattt
    62041 cttaattata tctataccac tttcattaga ttgaaattta ctcgctttta cttttatacc
    62101 ctttatcttt tctatatttt tttctacaat tgactcaacc ttgtcaaaat ttataacatc
    62161 taaataagtt gattcattca atatatttag tccctcattt gtaacattta aaaaagaata
    62221 tacttctgtt ttacactcat ccatatactt ttttttaaaa tcatagtagt ttgagggacc
    62281 agctgtacct gcatcaaata taactgtaga acctttttca attccaattg aatcagaatc
    62341 catacctgta ggtaattttc tcttataaca atgggtgtga acatctataa atcctgggga
    62401 aatatacata ttatcggcat ttattatctc gaactcttta tttgtaagta atttttcttt
    62461 tcttattttc tctttaaggt tcaatccaat agcatatatt ttcccatgta aaaccaagat
    62521 atctcttttt tcaaatttga taccatctgt tggagatatt attgtcccat ttcttataag
    62581 taaatttttc atttattcca catcctaatt acaatataat ttctctaata gcttttctta
    62641 cataaagaaa ataagcctaa aaataaaaat attttagact tattcactat attatactat
    62701 attaattata ttaaattaaa taaaatcttt aatttacttt aagaagcaat taagtatttg
    62761 ttgctcggct tcttctttag taagacctaa tgtcatcatc tttagtattt ggtctcctgc
    62821 aatctttcca atagctgctt catgtactaa aagagcatct ggatgatttg cagcaatttc
    62881 aggtatagca ctaatttgag aatttcccat aattattgaa tcacattgaa catgtgcaga
    62941 acaaagggaa tccccaataa cacaaggatt aaacttttgc ttagaattat cttgcccaac
    63001 tgtacgagaa actacttgag cagaagagtt ttcaccctct aagataacct tcatattaga
    63061 ttctgcaact tgattaccat gagttaataa tttctcaaat acaactattt tagctccttt
    63121 acctaggttt gcatccattt ctcttttagt tgaatctaca cccttaattt gaattgtttc
    63181 catttcacaa tatgaatcct catccatatt gacaatagta actggattta aaattctctt
    63241 tccttctcca tcaccttcac cataatgttt ttctacatat tttaggcgag ctcctttacg
    63301 taagaaaaat ctatgtatac cattatgttc actatcatca caaccacagt tatgtatacc
    63361 acacccagca attataacaa catctgcatt ttctccaatt tcaaaatcat tatataccat
    63421 atcctgtaca ccagcctctg ttactattac tggtatatgt acattttctc cttttgtatt
    63481 tggctttact ataatatcta ttccaggttt atcagtttta ggaattatag ttacattttc
    63541 agttgaatgt ctctctactc cttgcccatt tttacgtata ttgtatgctc ctaatggagt
    63601 tccacgaagt tcagcaactt tttctaaaag atttaaatct attttgttca tttaatttgc
    63661 cttcctttct aattaattca tgtctttcat taattcacaa cttgaattaa cttgacacat
    63721 gatttcaggt aatatagcct cttttgttcc atggcttttt actgaaccat cttgtagaac
    63781 aattatttca tcagctaact ctaatattct ttcttggtga gaaattatga ttatagtctg
    63841 attagactct tcatgtattt tcttaaaact ttcattgagt tttccaaagc tccaaaggtc
    63901 tatccctgct tcaggttcat caaatataga aacctttaaa tctctagcaa aaagagttgc
    63961 tatctcaatt cttttcattt cccctccaga aagagagtta tcaacttcac gatttaaata
    64021 gtcttttgaa cacaatccaa catctgtaag gtattggcaa catacatcag tagacaatgg
    64081 ttttccatga gcaagtgtaa gtaaattttc aactgtcata ccttttattc ttggtggttg
    64141 ttgaaatgcg tatcctattc ctttttttgc tctttctgta atactaagat ttgttatatc
    64201 ttctccatct aaaattatct gaccactcgt agctttttca attcccataa taagcttagc
    64261 aattgtagat tttcctccac catttggacc tgtgataaca ataagttttc ccctctcaaa
    64321 tgaaaggcta acatcattta ttattcctag ttcctcattg ttagactcaa cattaaagga
    64381 aagatttttt atttcaagca taatacccct cttttctata aaatattaca ttaatatcca
    64441 ttcttttatt atatcagtaa tttttatata tcagcaactc taaggagata aaatgtatat
    64501 taaataataa aacaaagtta ttgaaaagta aaaaagatga gttttatgta aactcatctc
    64561 agaaatttag tatatcaact tatatgtatt taaaatttaa ccttctatat actctaatat
    64621 tattttttga ttatctttta acataatttc ttctttttta gattctattc cattcttttt
    64681 tatctttacc tcagctacaa aggcatcatt accttcaacc atttctaata gttcatatgc
    64741 ttttttacga cctattttag ttgctatatc ttttagtact gccattttct taaacatttt
    64801 atcacctcta ctcaaaattt acacttaatt tttaattata taattctaat cctagactag
    64861 tttataataa ttattgtctc taattatatc agatattgag taaatttaat actttgtaaa
    64921 attatttatc ctctctaacc aaataatcat ttccatcttg gtctttaaaa gaaaacatcc
    64981 ttccatatgg catctccatt aattccccaa cctcaacctc gttatttgcc atttgttcat
    65041 aagttccatt aatatctctt gtacttaaaa ttattgatgg atgagataca tttatctctt
    65101 tgttttgctt catcattaga tttttatcat acaacacaaa tgttgtaaat tcatttttac
    65161 ttggtgctac ttccacccat ttcatatttg gacccatttc cttttcataa gttactacaa
    65221 agttcaattt ttctgtccaa aataactttg catcctcttg attatttaca tagagagtta
    65281 tttttcctat tttatttatc ataacaatac ccacctttat tattaaataa atacctaata
    65341 ttttttatat ttaataatat acccatatat attattttct atagatatat atttctaata
    65401 tttatcgcca aattatgtaa ttctgctcaa tatataattt ataatatcca tactattata
    65461 gcctttattt atgtaattta atcaccttat atatcatact tataattatg acaataacta
    65521 cataaaaaat cacttctaaa tagagttatc catctaaaag tgatttcata tattctatgc
    65581 aactttgtgt tttagccact ttgttcctct taatcttaaa caatataaag tccctctaac
    65641 aagccaatca gtatacatac ctatccaaat tcctaacact ccaaattcta atacaacccc
    65701 caatacgtaa cctgtaaaaa ttctaaaaat ccacatacct attactgcag tcatcattgt
    65761 atatctagta tcaccggctc cctttagccc tgctgataat acaaaggata taggccatat
    65821 taccatagct aaacaatcac ttcgaattaa ttgtgttgag atgtcaatta cactagcatt
    65881 ttgagtatac atacttgaaa tccagggtgc aattggtata aatatagctc ctactataaa
    65941 taaacaaatt gttgcaaatt tagttaaata taataaagta ctcttagctc ctttaatatc
    66001 tccacgtcct atatactgtc ccaccaaggt tgtagcagac aaagctaaag cattcccaat
    66061 tacatttatt atggatgcaa ttgacattcc tattgcattg gatgcaattg ctgatgttcc
    66121 catagtaact ataaatactt gaacaatcaa tttacctgca ttaaaaagta gttgttcaac
    66181 tccagctggt attcctatat taaatataga cttttgagtt tcaacatcaa tcttaaatgg
    66241 aaatatttta cccatagata taaattcgtt tcctttaaat aaagctctta taattactat
    66301 acatccaatt attctagcta tagcaataga tatagctgca cctgttatgc cataggatgg
    66361 tgtttgcaaa tttattccta gaggatttaa atcaatacca tatataagta tatatcccaa
    66421 tgttacattt actatattca taaacatagt cacatacata ggtttcttta catctccaca
    66481 ccctcttaaa ataccatttg ctatttgttg tgtcgcaata aatggatacg taaataatgt
    66541 aaactctatg tataattttg catttgattt taccaattct tctgcggaac cataaaataa
    66601 attaattaca ccagttctaa aaacccacat caatattgtt attgtaaagg ataatattac
    66661 tccagacact agagcctgct taatagtttc attcaccttt tcactatctt tttttcctat
    66721 ttgttgagct acaacaacag tagctccaac agatagtgca gcaaatacag atataaatat
    66781 attgtttatt gaatcaacca ttccaactgc agatacagct tcttccccaa tatgacctgc
    66841 catcattgta ttaaatactc ctaaaagcat gacaaacgtc tgctctatca ttataggaat
    66901 tgctaacttt ataacatttt tccttataaa catccctatt cctcttttcc ctctttatat
    66961 aaatttaatt tttaattagt ttatcgaact gtaaattgac aatgcaaagt ttagaattgt
    67021 attgttcgca ttataatata ctgctttcaa ataatataaa tcttgtttaa tatcatttga
    67081 acacagtata tctttataat tatcttatgt ttattatttt ttatggatac cacatttaaa
    67141 atatttatta atttaatata aatattttcc gttattatta aaagtagcta tatttcgtta
    67201 atattgtatc actatcgtgt agcaataaca ataagtacat tttatatatt ttttataata
    67261 ttatttaatc atccaaactt ttaccacttt ttcaatatat aaaatattac actttagatg
    67321 taacaaaatc gcatccattt aaatattgta ttttatagac taattttagg atgtgatact
    67381 ttggttaatt taaatgcaaa taatctaaat gtaaatatgg tttatcctat ttcttccaca
    67441 gcacccatac gtttcagaag atatactgtt tcatatttag aaaacatgga aaatatttat
    67501 ttaactatag caacatactt tgatacactt ggtttaggca caatgaatat tgacaaagtt
    67561 tatggtcaat gggcttggtt tactgataat atatatgatt taaatctatt tgtttttgta
    67621 ggaaattatc cttatcaaat tgctaaaaac agatatgata catttgtaga tattttgcca
    67681 gtagctatta cttctattgt caatggagat agagtatttt taatttcaaa tccttgtttg
    67741 ttaaattcaa aaattacagt tagatttata tctagtcatc ctactcttaa tagaacagtt
    67801 gattatggca atattagaga ttttattttt taaaactgca acatgatgtg ctattaaaaa
    67861 ataccctaaa tttaatgata ttattaaata actagaatat ttttaattgg cacatcatgc
    67921 ctagctatta taaattcata atattatttt acttaagata agtactgtat tttatctatt
    67981 tgtatatttt tatttaccta gtttctcagt tctatatcct atttctttat tagctagctt
    68041 ataaccttct tgtatcattt cttctctcgt taatgcactc cctaataaat tgtcaatact
    68101 cagttgcttt ctatcactaa aatacttatc caataatgat tcctctatat cttcctgata
    68161 tgccaaattt ccttcatgca ttatatattt tacatcaaaa ccttctttat ttaatacttt
    68221 tcccaccaag atacttctat gacatcttat aggttcttgc atagctccta ataaaactat
    68281 cctataaccc atttgacaac ccttttttaa tctttctatt ccgtttaaaa aaatatcttc
    68341 ttttgctact ttctcaaaat ctgcataacc ttcttgcgta tatacatctt tattagttct
    68401 tttagctcca aattcttttc ccatgtatat atataaaaat ccggaatttc taagagattc
    68461 gttaaatgcc tctttattgt attgaatatt atatttagaa tatggagttt ctctaatgtc
    68521 aactacacaa tttatgtcat atttttttat catattaata agcttatcat atggataatt
    68581 tgaatgtcct attgcgaata tttccatata aacaccctcc tattctttga aattagtatc
    68641 tatatatgta gatacccgat ttacttaaaa ttaaataaag tattacttta aatacccaat
    68701 atcttttttt cttgatattg tatatttttt tactttatat ccttaaaaaa atatacaact
    68761 ttatatataa aacatcaata tttatatata ttttgtatat taaatacaat tatttataaa
    68821 gtctttaata aaaatttata aatagagcat ctttagaaaa ctattataat aaaaaaataa
    68881 gaggctgtct aaaaatatag ataagccttt tttcataatc gtaattataa aaatatactt
    68941 gatttcatat gaaaaagagt gtctcataaa ctaaaatgtt tactttgaga caccaccttt
    69001 tttattctta tttatacttt gtagacatat tataacatgc gtttcactgg tatctgaact
    69061 tctgtcaacc agtcttcttc actctcttta ttccatatac catctatata agattctcta
    69121 ggatttccaa ccactttata tttattatcc tctatccatt taaatgcatc tgcgtaagtt
    69181 tttcctaatg ttgaatatgg accattgtgt aatatacaaa ctgcattttc aactgcatct
    69241 aattctttaa attttaatat atccgtatct tcctttaaat catttatagc ttgacacatt
    69301 tcaacatcca tatcagtctc tctatattca ccatcatgat atatattaaa acaataatca
    69361 ggaactgcac atgtacaccc tgttttcatc atttcttcag ccattacatt tggaaataga
    69421 ttaaaaagtt catcataccc ctttaacact tttctcatag aagcaacttt aacttttggt
    69481 aaagacttaa taattacatc attcatattg acttctcctt tcaaattcat aaggtaatta
    69541 cgtagtttaa ttattttata ttcttcactt ttaattacat ccaacatttc tttttcttta
    69601 ttcattaaaa tattttcaac ttcttcagga ttttctacag ctttttttat ctcagctaat
    69661 gataaaccca tttgttttaa agttattatc tgatgtaatt taggtaattg ctctgttgta
    69721 taatacctat attttgtaaa ttcatctaca tattctggtt ttaacaaccc tatatcttca
    69781 taatacctta atgtctttgt agttatttta tttattttag aaaacattcc tatagaaaac
    69841 atctcatcac ctgcgcatta gatttgatta atttaagttt aaactttccc cttaggttaa
    69901 agtcaataca aaataaatta taattgtatt aattcttcaa ttctatctcc actcaatacc
    69961 aaaatatccc ctgtttttat aatggttgaa cctttaggta ttaaaacctg ttcctttctt
    70021 tttatcataa ctattaatat atcgtctggt atattagaat ctattatact cttattagcc
    70081 catttattac cctcatcaac atttacttcg ataagtttag agctaatttc tccatcataa
    70141 tcattaaatg tttttaatac aggtgtatta tcatcaacta aatccaactt tctggctaca
    70201 gttggtatca atgaaccttg tattcctact gaaagcaacg ctataaaaaa tattatatgg
    70261 aatatgtcat tctctatggc tactccttga gtaacagcat aaattgcaaa aactactgaa
    70321 gccgcacctc taagacctac ccacgatatg aataattttt ctttatttga gaatttaaat
    70381 tttgctagaa ctataaatgt tgctaatggt cttgcaataa ctatcatgaa tatagatatg
    70441 gccattgcta taccaaatac atttggtaac ttagaaggga aagataacaa tcctaacata
    70501 aagaataaca ttatttgcat aatccatgaa attccatcaa agaaatgaac caaacttttt
    70561 ttaagaggta tcctactatt tcctataata atacctgaaa tgtaaacact taaatatcca
    70621 tttcctccaa gatactcgct aaatgcataa gaaagtattg caatagctgt tataaatata
    70681 gtataaaatc cttctatctc gaagtttgaa tgtcttaaaa tataaacaga taattttgct
    70741 agtataaatc ctatagctaa cccaaaagct atttgtttta ttaccattgg tgcaataagt
    70801 tctaccccag aattattcat caatgtcaaa agaattagtg tcagcatata cgctattggg
    70861 tcattacttc cactttcaac ttctaataat gatgcaagtg aaccctttaa gtttagtttt
    70921 tgagaacgca acacagcaaa cacagatgca gcatctgttg aagctgcaat tgccccaatt
    70981 aataaacctt caagtaaact agttcctatt accatgtggc aaaacatacc tgtaacccca
    71041 gccgtaatta ttacacccag tgaagacatt aatatagaag gtatagcaac aggtttagcc
    71101 atattccagt ttgttccaaa ccctccaaaa aacattataa atattagtcc aatagaacat
    71161 aattgttttg tcagttcata gttatcaaaa tagattccta ccatcccatc agacccaaat
    71221 aacatcccta gtaagataaa aatcaataat attggtactc caaatttata caataccttg
    71281 ctagaagtta tacaaatcaa tagtactaac ccacttataa tcattaattc tgtcatagca
    71341 tcaactccat ttcatataaa ttttgtagat taatttacat ctacaatttt attacttatt
    71401 caaatataac atgacataaa ttttataagt tatggtacat aaagttcaac aaaaatttca
    71461 caatacatta aaatgtgagt gttatactta aatttatata tttgttttaa ttatattcat
    71521 ttaatattta taatttgaat ttttttttat taacatttca tttttcagtt gattgtttaa
    71581 tatatttcat tttttatagt aattttatat ataactacga aatataaagt aattagataa
    71641 gtaacaagaa actaacatgt aatgttagct actctagata tgaaatctta aaacttttaa
    71701 atattgaaat atttctttat atatattatt gtatatttct tataaattat tgtcaattta
    71761 ttttttctta aaaataaaat aattgcataa tttatttcaa attatgcaat ttataaaatt
    71821 tattcccaaa actcttttac tgcttcgatt atctcactat aaggcaataa agtcgcttcg
    71881 attattgatt tatttgtctt ttctaaataa tacttaatca tataatatcc acaagcatat
    71941 cctgcacaat aaggcaaccc tactggaaaa tatccttgca ttttagctat atcatcacca
    72001 taaagataag atgttatatt ttgaaatcca gtttctttta aagcactttt tattattggc
    72061 tttatataag tatttaatgt ttcgatatct gttctactga cccaaggtcc taacatttcc
    72121 tctccaaaca tccatgttgc aaaattttct gcaagacctt catttatcat catttcttct
    72181 aatgttatat tattattcca ctctataaac tgaaatctaa tattgtgatt acattcatgt
    72241 gctattaata ctggtaatct attgatagta tattcattag gaaccaatga tagaaatata
    72301 tatccaggaa tcccaccatc accccagtat ccatcactta atattgtata aggactattt
    72361 ggattcgcca ataatattga atatttatag tccttaatgt ttaaatcata cccttctttt
    72421 ataaaagcat ttatagagtt ttctatggtt tctttgcaag tgccccaaat tttatcagca
    72481 gataacacat ttatattctt tttttgcttt tcatcaatat ccttaggcga taaaacccct
    72541 aacatttcac ttgctataat tacatcatat ccacctttct gtctagcaac tattggaaca
    72601 ttcatacact tccacttaaa ttcaaaaggc ttcattaatt catatctgta tatatcttct
    72661 tttttgttta ttggtgcatc cattatcttc ttgtatattt tatctgagcg aatttctata
    72721 atattcatat ttaccatctc ctttaagaca aagtatatac aattacgtag cgtcaatgtc
    72781 aatatacatt ttttataatg tcaccttaat ctttttatta tattttatcc tgtaaacctt
    72841 ccgtacatat aacatttttt taaattaata aatttgtata atataataat aaaaaattat
    72901 atacttcaag gtttccctat gatacaattt actaaatcat aatttagatt atcaggtgca
    72961 actataaatt attctatatc aaggaggata tattggtcat gctaactcca tatttaatat
    73021 ttaatggtac ttgtgaaaaa gcatttaatt tttatgctga ggctttcgga ggaggaaaaa
    73081 ctatatttgc gcgattagac agcaatccaa acaatcctat tatgcacgca agtgttactt
    73141 tcacaaaata cgaaggttgt ataatgggtg cggatacaga caagcctgtt gtaatttctg
    73201 gcatggcgat ttgtgttgtt ctaccatctc gagaagcgat agaagaaata tctgtaaaac
    73261 ttgccgaagg tggtacactt gtacaagaat ttttaccaca cccaccacca catcaaaatg
    73321 atggcgctgc tgaagtactt gataggtatg ggtatacttg gtatttaagt acatagttaa
    73381 aataaaaaaa ctacatctaa taatcataat atagaacaga taaatttcaa tttaatagtg
    73441 tagtaaaaaa gtcgtgtcct aagactgtca cgacttttat ttgtataaaa atttaagtaa
    73501 atatttttgc gaataagtgg gaagtataac tttaaattaa tttcatatgt agtattggaa
    73561 atgggttccc ttgtccatct atttcagacc tatcaaacac tttaaatcct aagtgaatat
    73621 aaaatcctac agctttttta ttctgctcat ttacatcaac atattttaca ttgtatttat
    73681 ctatagcata ttttattaat tttttaccaa taccatttcc tctatattta tcttctataa
    73741 agagcatctc aattttatct ttatctattc ctataaagcc ctttattata tcattatctt
    73801 ttatacaaac tatattttct acttctttaa gtccaatctc aactaatggt atcaaagatt
    73861 caatatcttt ttctgttaaa aaatcatgcg ttgctcttac tgatgattcc cagacttgca
    73921 acatttcgtc atattctgtt gaatttattt gtttcatttc aagaattatt ccagatttca
    73981 taaaaatttc ctccctatat cacttttaat tgcataacac ttttttatac aaaacttaga
    74041 aaggactacg aaggttaaat atcatagtcc tcattaagtt taaatattat ctattatata
    74101 ttatactata atctagcaaa ttcactacaa taattcacat cagcttatac taaaggtgct
    74161 tctatttgag tagtaaaaag gaatttatga caatgaccat cattaacagt agtttctcca
    74221 catattaagt gaatgtgttt atcagttcca ggtattctaa ttgctggccc tgttgtaaca
    74281 catatcttat ggaaatggtc aaggaaatct acattatcat ttattttatg aacatgattt
    74341 gtacctccat ttattggtat aacttcacca gtaacccctg ctgcacggtg gttatgtcta
    74401 tcctcacatt cttctgctaa cttaacactt tctgaatatt catgaacatg tgtcatttcc
    74461 tcataatcat tatagcactt gttgcactta ttgtatttat aatcatcata cacataatct
    74521 ctttcacatt tataattttg ataactcatt tttatatctc tccctatatt atattaagaa
    74581 attcttgtaa agaatctcta atgtataata tgaattaaag tcaaaaaagt tcatattttg
    74641 taaaattatg tattaattta attatttttc ccagtattta gggcgtatta gtgaagctgg
    74701 taacttcgta ctagaatctc cttttgcagt atttacttgt aattgtgtta aaaatatact
    74761 attttcaaga ttagcacctc taatatcaca atctcttaag tctgctccta ttaaatttgc
    74821 cccactcaaa tctgtatttc ttaaatttgc tgctattaga aatctacctc ttaaatctgc
    74881 tcctattaga tttatttttc taaggtctgc tcctattaaa tctatatttt tacttaattt
    74941 tttcatgttt ttaagagtag aagtcttgat aaatgattta acctttccca tcatagactc
    75001 actcgcttgt gataataata aattaacctt tgttctatgt gatatgatat ccaaattaat
    75061 tatctgttct gggcccatat tagttatctt ttcagtttct tcaattatta aatcaatttt
    75121 tgatttgatt gtatctgata tatttaatac agatgcttct ttaagatacc ataacatttc
    75181 atgtaattgt ctcataatta aaaacacttc agacatttga tttgttagtt ctggtgattg
    75241 catccagtct atccccttat atgttacttg tgctactttt tgacctgaac caaaacaatc
    75301 atatgcagta caccctttaa aacctcgctt aataagacta ttatgtacag aacatttaaa
    75361 atctggttgt aaattaatac agggttttcc tgattcctta ttgataggaa atccatctga
    75421 agcagaaaaa taaagagcta cacagcaaag tccaaagcac ttcttacagt caatctttag
    75481 ctcctcaaat aacttattat catatatatt tttatgtata tctatcatat tttttctcct
    75541 cttaaacttt atttttaata ttatattatc tataactaaa tgataatcaa gtcccttatt
    75601 taacagttct tattcttaat tataatttaa ggtattattt attccaatag catacataag
    75661 tttctttata cttgtaacaa tacctttata ctaagactta ttttaaatgt agcactgtaa
    75721 taataaattg tttatatact cataatgtat ttgataaatt gtaaatcttt atagaagttg
    75781 aaatttttaa tgattttaga atcaagatat aataataaat acaatttata aaatcagaaa
    75841 tatataaatt aactatacaa acctaaataa catagcattt aaatttacaa tttcagtata
    75901 aatagtacaa agtatattag tttaaataag attggcttat ttgtagagga gagaatattt
    75961 tggtgttcaa taaaatttat atttaataaa accataagaa aatataaaga taaataaaca
    76021 aacttttatt acttaataga ttcttatggt tttatactgt actgaaaaac aataaacact
    76081 acagcttatt tataatatta cgctttttta acaacagaag actttagctt catagctcca
    76141 aaaccatcta tcttacattc tatatcatgt ccatctgatg agtcatggat taaacggata
    76201 tttttcactt ttgttccaat ctttatagat gatgaacttc cttttacttt aaggtctcta
    76261 attactgtaa cagaatctcc atcatttaat acatttccat ttacatcttt gataatattt
    76321 gaatcttctt cagctcccaa tcctaatgcc cactcatgag agcattctgg acaaactaaa
    76381 agagttccat cttcataagt atattctgaa ttacatttcg ggcaatttgg taaattttcc
    76441 atctttatat gtcctccatt tgttattttt agatttctta ttatataaaa tttcttttga
    76501 gcctttatga tatcatatta tacttatatt tacaaactac taatttactt aatgtttaaa
    76561 ttctattcgt attattatta aacttaattt agctgtaatc tctttcttat atttattata
    76621 gtttatatta ttacaatttt ataactctat ctgcctgctc cgataaatct aaatcatgag
    76681 ttacaaatac gatagtttta ccattcttat ttagactttt aagtatatca aatactatgt
    76741 ctctattttt tttatctaaa ttacctgtag gttcatctgc aaatattact tcacattctt
    76801 ttaatattac tcttgctaat gctacccttt gttgttctcc tccactcaat tcgtatatct
    76861 tttttttatt gtattttcta agacctacag actcaagtgc gtaatttatt ttttcattat
    76921 gattgatatt tttttgatac tttaaagcaa ttttcaagtt attttcaaca ttttcattct
    76981 caattaaagc ataattttga aatagatagc cataaaaatc cctttgtaaa attcttatct
    77041 gtttactatt tggatttttt atattattta ttataatatc accagaatta ggtttttcta
    77101 ataatcccat tatattaagt aaagttgtct tacctgaacc actatttcct gttatcgcta
    77161 caaactcgcc cttagaaatt tctaggttaa atttgtctat tatagattta tctttaaatt
    77221 ttttagatat atttattaat gaaatcatct ttttaatgtt ctccttttat aattttatta
    77281 aatgaactat ttgagataat cttgtctaat acaatagata caattacttc tataactaat
    77341 attagaagtc caaataagat aatattatta cttaaatcta ctcttgttga tataatgcct
    77401 attggaataa tgtttgttaa tattaatgag actattaaca acatacttct agctgtagtt
    77461 gagtaaccaa atattttttt aatatataac ttatatttat ttctttcata gtagctagct
    77521 actatattgt aggtaatcat taagtttgat attgctatta ttattatagt aaaaatttca
    77581 ctattcaaat atttttctag tttatttatt tctaaaccat actcattata aacagcatgt
    77641 aaactttgga tatgcgcttc tacaccttga gcttcaataa tgctacttat atctgcaagg
    77701 gcatctaatt tcttagaatt aaaatataca catctagata tataagaaag ataaaaagaa
    77761 tcatcaatat tatctatgtc aactattgct attgggtcat caatgagatt cctattgtca
    77821 tccataacaa gggagttata agtaaaatag ctttgattat tatctacata tattatatta
    77881 acatttaaat cggacttctt tgttttattt aactctctat ttaactcttt attgtacata
    77941 ttttctactt ctattttttc aaaataaaat aattctctaa actctttttt aatctcattt
    78001 tcatgtactt gtaacttttt aggaactaat aaatttatag tcttatcgtc ataatcgatt
    78061 agattaaata tttctttgcc atttgagtaa atagggttaa ctttaagata gtttttattt
    78121 atttttatat ttttaccata ttgacttact tctgggtttt taccctttga atttatttca
    78181 tacatgtaac ttccatcttc aagtttttca aaattagttg aatctattaa gaaagcatct
    78241 ttttcttcta ccaaattttt atagaaacct ttaatcttgg catttttaat tacttcttcc
    78301 tttcctaaag attgttcgcc tgtatcttta agagtaagat tataaacatt ttttgcttta
    78361 tcccactcag atagatttcc taactgagtt tgtagcatat tataatttaa aatacagtta
    78421 tttatggata atataagaaa tgatacaaat acaattttca atgtgaaatg cattatattt
    78481 acaaaaccat aagatttttt tccatttaga gatagcacat atttagaact tctactatta
    78541 aaaccaacta ttaatataga tatcaaaata tttatcaaaa tacatataat cgaaaacata
    78601 gcaaagtata agcatgctct aacacctata tttaatttta aaatatagat tatatatatt
    78661 aataatgctg tgacagatga taaaatcata attctaagta tattttttat aactctagca
    78721 attatatcta gcttagagta tccatttaat cttaaaatag aagcctctct actcacacta
    78781 attgaataat gtattattgt agccaagaaa caaaggataa ttagtattaa atctctaatt
    78841 attgaaggat ttaagtataa atttgagtta acatatctat catgtaatct tgctacaaaa
    78901 atacttctgt ctacatttag ttctcttaat attttattta ttgtatcttc attttgagtt
    78961 gaaatatata agattcctga ttctccaact tcacttattt taccaaaatc cctaattaaa
    79021 attgatatgt ctttactcat agttgagaat ttacctactt gattactatt attagtgttt
    79081 atattactaa taaattcatt tgaattagta ttaggaaatt ttcctgattt taactttata
    79141 ttgttattca aacttgtatc agtcgtatat atagataatt tttcattatt attaaaaaca
    79201 tactttgata tagccacatt attttcatct gcaatatctt taatccactt actataattt
    79261 ttatttaact ttttataatc tttaaacatt acagatatac ttgttgtatc gttatataaa
    79321 atattattaa tttcattatc tttaactata tttagaccta ataaagatac tattaatagt
    79381 tcaattgtaa ataatacata tattatcttt ttcaattata gctccctcct aattgttttt
    79441 attctaaaag caaaatacat tttactttag ttaaagtata atgctttgtg ccttttctaa
    79501 acaactacta tattgtcaca ttctaaatgg caagtgtcta tttcgtcaca aagataaaaa
    79561 tagccttaaa gcagttaatt ttttataatc aactgtttta aggctatttt ttatttttag
    79621 caaacaatat tttaatagtg gtataaaatt agtataattc attaatatag attctagtct
    79681 tttcagtaag caactaaaat aatatcttat ttaaaacgaa atttaattta agtccaatat
    79741 aaactttact ttaccattaa atcgtgctag tacataggta tgcttctttt ttattccata
    79801 taatggatat cttatgaata tctatagaat caagataata aggttgtcca atttggaatt
    79861 tagaatatgt atttttaaat tttttattta catataataa aaaattattt tctttattaa
    79921 tcacacaaat acactggtca atattatcta aaatattctg gtattgttga atctgttgat
    79981 taagtttatt atttttttta cgttgtaaaa acattgatat aatttgagaa atcaatgata
    80041 atgtacttat ttcctcttgt gaccatagac gtagtcctgt gcattcatca aatccaacaa
    80101 atccactgaa aactctatct tctttatatg cacattgaag tgtagagtgg ataccttgac
    80161 tagaaaacaa ttcttctagt ttaggactta atgtatggat atctcgacaa taaaaaacta
    80221 attcatcctc aaaaagcttt tcataatcct catagtcttg ataattgctg ttttgcaaat
    80281 aagccatttg agaagagatt ccttcattac accattcata agtattagaa gtatatctac
    80341 catcttctgt attttcaaaa atataaacac gacttacatc aaactgtttc ccaacaacct
    80401 caagtatcat attaatcgcc tggtctatat catcagtctg ataaagcata cggaatatat
    80461 aacgtgtaag attatcagga tattcagcgt attgtttttc tgaatcaata actgtaccaa
    80521 gagaagaaca atcaaattct tctaattctt taaaataatc ttggttgtag attacataat
    80581 tattttttcc catatttttt gcttgataca gggctttatc agctcttgca tatatttcct
    80641 tgaatgtagt accatccttt ggatatatag ctattcctat gctacaagtt acttttagaa
    80701 aacttttttc tttctgaaat agatgacgga acatatacaa tagttcttct gctttctttt
    80761 ctgcatcttt aactgaggaa atattcttca taaaaattgt aaactcatct ccacctattc
    80821 ttccaacaac atcactgtca cgcattattt ttttcatacc tgatgccatc tcagtaagta
    80881 ctatatctcc aatcatatgc ccttctgtat cattaatctg tttaaaatta tctgtatcaa
    80941 tcataaacag tgcacccata acatttaaat ttttttcaaa atatttctta atctgccttt
    81001 cagtctcagc acgattataa attcctgtta atgcatcttt ctctgatata tgctgtaatt
    81061 tctcaatctg ttttctttcc tttgttatgt caatacctat actataaaaa gatggtattc
    81121 catcccaact gtcttcccca ctgatataac acaatgtaac agtccatata cgttcttccc
    81181 ttgaacgtgt atatattttt gcttcaaata caacattatc cccagactcc ttcaaatctt
    81241 gtgccagttt cttactacgt ttataatctt cagaaaataa atatccacat tgattattaa
    81301 gttcctctgc aaactgttcc tttgtatatt caatcatatt caaaaatata tcattacacc
    81361 aaagtatagt aagataatct cttgcatcta atctaaccat tcctgctgga atagttttca
    81421 aaattgattc tctttcctga tctttttttg ctaatttata ttcagcacta tacatatcat
    81481 aagataattc aatacgaact cttcgccctt gccaattcaa catacggtct ttaattataa
    81541 atgttcgttt cagtttttta ttataaaatt cccattcata tatgtcatct ttttttaaat
    81601 acgaatttgt acaaaacgga catggcgaag ttctaccttg aattacctca taacattttc
    81661 ttccaataag ttcatttgct gatgcctgta aagtattgca tgagtgctta tttaagtata
    81721 gtaattcata tgtatccata tcgctaatat aaacattccc agcatactct gacatcatcc
    81781 atttaaaatt ctctgtactc tctttttcca tatcagatag ttcttcttgc tttattttta
    81841 actcattaat ttttgaatac aatatataga ccattgattt ctcattatct tgtgattcaa
    81901 ttaatatacc agtcattatt acccaaacag ggtctccatt atttgctgaa atgcaaattt
    81961 gatattctat actcttttcg ccatgatgat aagcctctaa aaaatgattt ttcatagatt
    82021 caaaatgata aagattctgt tcataataat cttttaaact agaaaattta actaaaaatt
    82081 cttcttctgt atatcctaat aattgataga atgatgtatt tccccatatt attgtaaatg
    82141 aatcatctaa aaaatgttta ctgaccccaa tactcataga ttttagaata tcctctgata
    82201 taacttcatt ctttgttgct tgttcttttt tacacattcg atgtaaccta atgtcttctt
    82261 tcattgtttt aattatcctc ctatctttag actcactttt aattcactct gctttttaat
    82321 ataatgataa aagtgaatct tcaacgtgta taaattgatt tcatttacaa ttatttttgt
    82381 ttgaaattga attttcacac acacttgcta agattctccc tctaaaactt ttaatttagt
    82441 aatttttttg atgccctatt caccatttaa tatcttaatt atcgattctt gttcacttaa
    82501 atctgtattt aacttttccc ctaaaaacac attattttct catatttact aaaaatcgcc
    82561 ttcttttaat gaaattatat cataacttaa gttttaaatc atttttttcc agatagaaaa
    82621 attaagataa aattactgaa attatatgta atataataga aatgtaaact gttttaaatt
    82681 tgaataatat taaaaaggct gtatcatagt aattataaga tactatgata cagccctatg
    82741 ttaaattttt cttacatttt taatgatttc acgaatcttt ttagcatttt tagcaatatc
    82801 ttcaacagaa cctttagtta ataaaccacc aaatccacat acatcaactc cattttctaa
    82861 ccatatatgt aggttttcaa tattaagccc tccacttgct aaaactggca tatcaggtat
    82921 tggtgtctta aataccttta ctagtttagg tccatagaaa tctgatattg ggaaagcttt
    82981 tataaaagtt gctcctaaac ttagtgcgtc tactgcctca gtcaatgatg tacatcctgg
    83041 agcataagga atctgatatc tattgcaaat cttcgctaca ccttcattat aatttggtgc
    83101 aataataaat tgggctccat gtaatatagc atgacgagct gtttcactat ccaaaactgt
    83161 tcctgctccc acacaaagta tttcaccata ctttttatta agcccttgaa ttatttctcc
    83221 agcattattt agggtataac tcatttctat aactgttata ccacctttta tacatccttc
    83281 agcaatttca catgcacggt taagattttc ttctcttaca attgcaagag ccccacattc
    83341 tgacattctt ttggttatat tcatcttttt catattatca cctctatact catcaaacca
    83401 ctttacttat tcattaattt tagtcatgtt ttataatata tatattaatt atataccagt
    83461 gtaatttccc tatttatatt atctattctc actactttta ttaagtattg tcctataatt
    83521 ttcaactact cgtttaattt cttcaagtac ttccccagtt ggttcagtta caggaagtcg
    83581 tgcagttcca acattaattc cattcaagac aatagttttc ttcataacag atggaattgt
    83641 tccaagtttc agtatacgtc gaagttcttc tatactactt tgagattttt gagcttcttc
    83701 caaatcccct ttcataaagt tttcatagat agagatacca atctctgtga ggaagtttgt
    83761 tgttgctgca acagctcctt ggctaccagc ttttagacta tccagaataa gtgaatctga
    83821 gcctgaaaac acactaaaat tctcattctt cgttgcttca atataagctt tcatgttgtc
    83881 aagtttacca ctactatcct taattccaac aatattcttt atctttgata attcacgtac
    83941 tgactctggt tcaatattaa ttccagtctt acctggcata ttatacatta taataggtaa
    84001 attaactgaa ttagcaatag ttttgtaatg taagattaat tcctgttgtg ttggtgtaac
    84061 aaagtatggt gtaataatag ataatgcact tgctccaatc gcttccattc tcttagataa
    84121 atctacaact tcacgagttg aattaccccc tgttccaaca aaaacaggta cacgattatt
    84181 tgtatgatta ataacaatct ttgcaaattc aactttttca tcatctgtta atacatgaca
    84241 ttcaccatta gtgcccaaaa taaataatcc ataaattccc ttttcaatca aataatcaat
    84301 taattgacat gttgcttgtg aattaatatt ttgattttca tcaaatggtg ttatcattgc
    84361 acatataatc cctttatatt tcataaaatt atattccctc tctaatagac tttccaagac
    84421 ttcctgctgg atgccacttc aaatactcct gtgtattaag acctttagca tattgtaata
    84481 caacacttaa tgattgtaat attattgttt cagctaaaat tgaagcacga ggagctttat
    84541 tgagacaatc tccttcctgc ttaacacctg caaacaggaa tatatcagaa atatttttta
    84601 aaaatgaact ctcattacca cttacaccaa ttatctttgc tccatttact tttagagtct
    84661 taagagttgc ttttaactct tgagtttcac cactatttga tattgcaata acaacatctc
    84721 cttcaactac ttgaccactt gacccatgta ctgcttctgt accatgcaat atatatgctg
    84781 acgttccagt agatgaaagc aatgatgaaa tatatcccga tacatgtcct ggtttgccaa
    84841 taccagtcac atgtacacgt ccgtgatttt tttcagcttc aagaattaat tcgcatgctt
    84901 tatttataga tgtctcatct attgaggcaa taaattctga caattcatta gatatattat
    84961 ctaaaaattc agataatgta ttttccataa gatgtatcct ccttgaaatc atagtaacta
    85021 tgactatact tttatataat ttagtctaaa taggttttat aaattgtaaa atattatgta
    85081 atatcgaacc aactacgttg taatcaatat tagggaaagt tgctccttct ataccaagag
    85141 tcccataaac tggatatagt ataactggta aaaatgcaag taataacccc acaacaaatg
    85201 acccagcaat agcccctctc catcctcctg aagtattgcc aaatattgca gctgtacctc
    85261 ctgagaagaa acatatgtga gcagctggaa taattactac aggaaatata ctaggaaatg
    85321 atgccataat agcaattgct aatagaccag aagcatatgc tgatataaac ccaataataa
    85381 ctgcatttgg tgcatatgga aatacggttg gaacatctag cgcaggacgt gaacctggaa
    85441 tatacttttc tgaaatgatt acaaatgctg cagttatttc agctaagaac atacgaactc
    85501 ctgacatcaa tattgacata cctgccacaa atgtaaatgc ctctataagc ggaaaaacca
    85561 accaatgtgt tgaaccagca atttcttgag taaatgcttg accagctttt aatgttgcaa
    85621 tataaaataa gattaacata actatggata gacccattaa gaagtctctg aatattgata
    85681 accacttagg aaattctata gtctctgttg tatcatcttt atgttttgaa aataaacgcc
    85741 caatataacc tgataaacaa taaccaatca tgttaaagtg accaatagct tgttcgtcgc
    85801 cacctgttaa ttcacgcata aatggttgac agaattgagg tagtgcagca gacataaacc
    85861 ctaagatagt tccacctatt aaaatagtga ttgtattatc aaatccatgt gctttcataa
    85921 ttaaaactaa tacacaagaa aagaacaaac tatgacctgt tgtaaagaaa atattcttaa
    85981 actttgtaat acgtgcaaat actaaattta atatgaatcc aagaattaat gtacatgaaa
    86041 ctgcaaaacc atatgtacct tgtgcaagtg ctgtagctgc ttctggtgaa gctataacac
    86101 cagtaattcc aaagccatgt tggaacagtt tattgaaatt ttgaagtgct cctgtcatag
    86161 cagaggcacc aataccaaat atcaaaaaac cgataagtgt ttttgaagag cctgtaaata
    86221 cttcaacagc tgatttcttt tgaagaatca atcctataca tgcaactacg ccaagcaaaa
    86281 cagcaggtgt actcagcaaa ctaataataa actccataaa tattcctcct tatcatctta
    86341 aatttatccc tcttttgaag caaggaattt ttctagtgct gtctttattt cattacggtc
    86401 aacaatattg tgaatcccaa ttatatcaaa cttcaaattt ttatttttta attcttcagc
    86461 aacatcaatt aatgtttcta cagcatctcc attgaatcca tttagtgaat ccaatgaacc
    86521 atgttctact tcaattggaa agttattttc cttaataatt tgttgagtct ttatttttaa
    86581 cattaaactt gagccaactc ctgctctaca tgcgattaaa attttataca taattaaatc
    86641 ctcctttata attcgtgtgt ttttataaaa tcaataattt ctttagcttc tttagcacta
    86701 tctaaaacct taaaaaactc atcttcttcc aatagttcaa ctagctcaga catagcacgt
    86761 aaatggctat tattgtctat tgcacttaga caaaatacat attttacagg gtcgttttcg
    86821 ttattcccaa actcaatagg actatctaaa gtagcaatgc ctattgcaat ctcttttgac
    86881 ccagcttctg gtctagcatg tggaagtgca acatgttttg taattactat gtatggtcca
    86941 gatgcttttg ctgagttaat catagcatct acataccctt cagttacttt gttattttca
    87001 actaatacag aagctgactg tctaatagct tcctcccaat tcttagcttt tacctttatt
    87061 tttactagtg tttcattagt aatctcactt agcataggcc cctctccttc cttagatgta
    87121 aaattctcta tctgtgtaaa ataagctaat agctcacttg aaagaatact ttcagaggtt
    87181 acatttgcat atttttttat tatatccata acctcatcta ttttaggttg tcttaaaaaa
    87241 atatcaccta attgaatata cacttcacgt gtaatcttat atttttcttt tgtggtcata
    87301 acagggctta ctttaattac tggtacatct gtttttaaac cctctgcgtt ataattagta
    87361 gtaaatacaa tatctacagg ttcacttata ttttctaatc caactgattc cgacattggt
    87421 ataaagtgta agtcaggaaa taagtttgta agttctgcat gtaaaatagc tgaactacca
    87481 acgccatttg aacaaactat taatgctatt ctttttctaa aaccatcaaa ttctttttta
    87541 tttgaaaaaa gtgttgcaaa gtgcattgta agatatgcta actcttcttc ctgaatttct
    87601 tctccaaata atccgcaaaa ctctttcatt gcattactta caattctata aactaattta
    87661 tattcttctt ttactttttc acaaatcgga ttataaatag gtaatttaaa taaaagtcta
    87721 tagtaggcag gtctaaaatg agaatataat tgtttaaata ttttttcttg gcttatatag
    87781 taaactccgc ttaaatatcc aaactttgtc atcattttat ttacaatttt tgaaattaca
    87841 tccttatctt ctgtatcttc ttcataattt cctactgata tacctaaaat ccaagcacta
    87901 atatacatta tattgtgagg ctttatctta tcttcactcc catatacttc taataattcc
    87961 ttagcaaatt tatactcctt cattgaactc ataactgaaa tattaggaat atctacattt
    88021 tcctgagtaa ctattctagt tgaatacatc cttgccttta gaaagataaa tatatatata
    88081 aattctacta atctatcttc aacaaaagta atttcatatt tttttattag ctttaatata
    88141 atttttttag cctcttcaaa actatctaaa ttatattctt taataaaaat atcaaatact
    88201 cttgaacttt tctcattaga caaagtttct ataatatttt taataagcac tctcctaatt
    88261 tccatctcat tgccaactat gtaatatcca tttatacgat tgttcttaac tttaatgttc
    88321 ttcttttcaa gctctggtat caaatccttg aaatcaagat ttacagtaga cctacttact
    88381 tttatagaat ttataaaatg attaattgaa atatcatcca tgttaataaa aagcattaaa
    88441 tacatatata aaagtctttc tgtcttacta aaataataag tattcttaga atagtttttt
    88501 tctaaaattt ctttaattgc tttttttgtt tcttttctaa cgataatatc tttatcagct
    88561 cttaaacata taagtggtac attttttact ttaagcatgt cattgatttt atttattcta
    88621 taagtaattt gtctctttga tgaattagac tcctcttgta atccattagt tgtaatcaat
    88681 gtgctattta ataaaatctg gagaattgat acaatttctt tgtccactac cattaacccc
    88741 tactttctta ttaagattag tcttcatatt atcattggat tctttcatca cctccacaat
    88801 acttatttta tttgagaatt ttatcgtttt caatttcatt taagtataac ttttgtttta
    88861 gattgataca aaaattaaac ttctctaaaa tagatactat aatataactg tagattttat
    88921 aaataaaaaa agtttcttta gacaaagaaa ctcaagaaaa attgatttaa ataataaaaa
    88981 tcatattgat tataaataaa ttactacaat taaaaagcac attaatttaa aataaaattg
    89041 atgtgcctta tctataatat aatatattta atctaatttt taacttggaa tttaacatcc
    89101 ttttttatga aatcaactta tgtacatata caattcatac tctattttta tttcattttt
    89161 ctaagtgttt cctctaatga aatacacttc gcatatcttt cattccatat aaattcattg
    89221 tagtatttat atgattgttc tgctgacata aaaaaattgt caacagttgt atttgaataa
    89281 gctggaacta ttatattaaa tccatgttca aatccacatt ttatagtggc atcaatacaa
    89341 taatctgttt ggagaccagc aataataata tctttttcac cattatttgt taggtattct
    89401 aatagaccag tttctttaaa agcactattt acttttttat caaatatttt ttctccatta
    89461 catggtttaa atttttcgta tatttcaaag ccatttttac ctttagtcaa ttcattttca
    89521 actccatcat catgacgtac atatattact tctatattat tttttctagc tgtatcaatt
    89581 aaattttcta catttactac aaattcatta aatttatata acctctcgtt tgttattaac
    89641 ttttgtgcat caacaatcag taaaaccatg tttattcctc cttggatgtt cttctaataa
    89701 tatctttata tcttaccata aagatatata ttactctcta atatttttat ataatacatt
    89761 tcctggattt ataactatta atgcaattgc aaatattaaa tataacattg catagtaatt
    89821 tataagctct attaaatctc cattaattat ccctattaaa aaattaaata gttgatgtat
    89881 tacaataggt attatcaaag ttttatttag attataaaaa gttgtcatta taatactgat
    89941 tgatataatt gcaatcataa aaaatataat atattttatt aaatcaagtc ctttgaatcc
    90001 tgttgtaaac catattggta aatgccacat cccccaccaa aaacctacta ttatggatgc
    90061 ttttaaagga gaatgtcttt tctgaagatg attttgaaca aatcctctcc aacctaattc
    90121 ctcacctaat gatcctgcaa ataaattttt taaaaataaa tatataaatg ctccccatga
    90181 tgaaactgta aagttaggca ttattccatg atttttagat gctaatataa atataactac
    90241 tacagctatt aggacttgta tactaattat tatagatact gttgaaaatt taagtttatt
    90301 tctaaatcta tcttttacgt gtactaaaaa tttcttacct ggataaattt ttttaaataa
    90361 tatcataaat gcaaaagtgg atgaccacgc tgatatacac aacgcaatgt cagatatcac
    90421 tgttggaagt tttaacatta tagtcactac taccaataaa aaaagtggta aaaaaattat
    90481 atttgttaga ataataaaac tggctatagg cctttttaat gatttctctg ttctcataag
    90541 taatcctcat ttcaaattaa tatttaattg ctatataagt tataactgct tatatcatga
    90601 gtttaaacct atgagtaagt cccaggtcaa tgcttttata ttattttata ggtgcataaa
    90661 tctctaaaaa tatacgctca atcccttctt cataagtagt aagcaatata ttaacataga
    90721 ctattccaag taattcacat tcattttcta ttgctatttc tcttaatctg tcttccactt
    90781 tattatcaat attttctcct ccagttgacc atctgccatc ttcaataata gtataaatac
    90841 aattgggatg agatagaact tcaccttcta tgattttgtt gtagtcatct acttccctta
    90901 caattataaa tttttcttct attatacctt cttcattaaa atttattact cttcttaaat
    90961 cagttaatgt aactgctttt tttaagttgt ttgtattctc ttttaaggct tcatattcct
    91021 catagttagt aacatgtttt attttacctt ttacttccaa aggcttcatt tcttttattg
    91081 tgtattttcc aaaatatgtt tttattttgt cacaatcttc tttgactaac tgaacctttt
    91141 ttaagagaag ctttttatat tctatctctt ttagtatgat ttgttccttc tcttctagta
    91201 agagttctaa attgtttata ctcttacttt ttcttatttc ttgaatcttt ttaatttcta
    91261 tatcaatttc tctataaaag tttattgttg caatatcata gatatcaacc tgattatata
    91321 ttctatatcc attttcatca tttttcttag gatttactaa tcctttgtcc tcataaaatt
    91381 ttagtgtatc tctagatatt cctaaaaatt tagatacttg tccaattgta tacattatat
    91441 tctcctatta ttagataaat tctttatgct cattaaacgt atttctatta acaattacaa
    91501 aatcacctaa actttgaagt atcaaagtca gcatagtatt tacaaccttt ggaattactc
    91561 tttttatttc ataatccaag tgtaaacttg ttaatatgat acgttataaa gactatattg
    91621 tctacatatt tctaacaatg attctttcac tttaagatgt tcttaaacat atttaacttt
    91681 tatttttaaa aatttcctat acataaaaat attcctttca tgataacagt tttattattt
    91741 caactatctg ctaccataaa aggaatatct taatctttaa acacattcta aatgctcttt
    91801 taacaaatat tatcaaatta ttctaattct attgtttcat atttattagt cttagtttta
    91861 tataaattta aatataaaac tatatattca cctactttta aggatacaat aagtcttctt
    91921 ctaccagtaa gagtaaatgc ctcctctact tatcacaaac tataattttt atctcattgg
    91981 tatatatcca cgatactgtg agtatgcatc catagttgct atatcaccta agaatactga
    92041 tgcgatattg aattgtggtt ttaaatatgg gaactcctct tcttgtgccc attctggttt
    92101 tttaataaac gactttgtct cttcaaccac agctttatac cattcttctt ccccttcaaa
    92161 ccatagttct gatacacggt caaaagcagt tgctccataa ttaatcatta ttttactact
    92221 gacaaaacga ttaacatagc aacagtttgt aaagtatggc actacctcat catagaacca
    92281 tttttctcct tcttctttag agataccatc tggatactta atcataaatt gccaacgata
    92341 gtttggtcca tcttgtacag tacgtccttt tcctctaaag tcttcttccc agtttattgg
    92401 aacaaaggca aatataaatg gtggacatcc attatctcca cctactgcac gtcctgcatc
    92461 tccactttct gcattttcat gaaccctttt attttctaca tctggtatac acccttgcca
    92521 acgtagaaca tccataggca tatattctgt cataattcta tttgccatct caggcatatg
    92581 ttcatctaca agccaataat gttctgttag ttgcatctta cgtgcaccaa aacgctcacc
    92641 ttcatttggt gtaggatatg cttgataaaa ggcatattta gtacaatatg gtccaaaagt
    92701 gctaatacta tctggaatat ggtgacgata taaccagtcc attagcttag gtctatattc
    92761 ttccttggca agtcctacat atattaaact tctcattatt ttaaattcaa aacccatagc
    92821 cattctccta taatcaaagt atattcacat gctttcaatt tccctttttc ctatctttac
    92881 tcaaaatata tattgtaaac aaatctacac ctgcacccac gtaccatact cctactgcca
    92941 tagctacagc aatttgaata caaatatctt gtaaattaat aatattttca cctgtcataa
    93001 tagttagacc tatagcccaa ccacaaagcc atgatggtag gaaaattatt ttttcaaata
    93061 aggatgcaat tacaactgca aaaaaaccta atatactaag tgttaaaaat aattctaggt
    93121 tttgattgaa attcatatat cccataatta aaatggctaa cactgcccat aaatctccac
    93181 accaaaaacc aaacattatt tttaatccat ctttttgttt attaccatta gttacatata
    93241 atcctgcaca gattagtgct acagctccag tttttattcc tatataaggt gctaatactg
    93301 cccataaagg aggtagtaaa gcaatcccca tagacagtgt taatatttct tttttctttc
    93361 tatccatttc ctatattgta attagtagct tccctagctt gccttatctc caatagctta
    93421 attgctattt gatttacaat catagatact gcaaaataac ttaaatatag tggtataaat
    93481 ataacaataa atgctggagt taatctaacc ttgtaatatg taagtaccaa aaaaataact
    93541 gctaaaataa tttcaatttg tttaaaactt gacttttcat tcatacaata agcctcctat
    93601 aacatctaac ataccttaaa aaagagtctt agtattttaa ttattatcct aatgaaactc
    93661 cagcttgctt ttctttagtt aatggctcta taaaattata agatgttttt ctttctttaa
    93721 attcttgtgt tttacgaact tctgcataat gaccttccat tttcttaata tcatcaccat
    93781 gtataaactt acctggtaaa gtatcatgag catgacctaa ttgctcttct ggaaaactaa
    93841 atatagtttt tccacttata gtatctaact ctccaactat accacataga gcacaaattg
    93901 cctttttagt acctggctca aggtagaata atctattgtg gcaatgtgga catacacctt
    93961 cttctccttg atatgaagct ttttcaaaat cttttgctgc ttcaactata tttaaaccaa
    94021 tttgatgaac ttgaacaagc cttgtatcat ccattactaa ttcctttgcc catgggaacc
    94081 aagcattatc tataactttc cacattggta tgagagctag catagcatgt tcacattgaa
    94141 ctcttgtacc ccagtcagaa cctcctattc ccataaatga tattacttta tcattaagca
    94201 ttcttgaatc tggaattttt cctcctatag cttctgcaac ttttgttcct ataatgttat
    94261 ttcctctatc tgctctgggt ccaaaacggt ccattatagt atggaataat cctgatgccc
    94321 cttcttcaaa aatagggtct gaaactacta taccatctgc atctttcatt ttgtcaagca
    94381 accattcaaa atcatctttt aatacacaca tactaccttt cccagataat aaagttttaa
    94441 cacacgcaca acatccagta caatgtttaa tgttaataga tgacatttga ataaattcta
    94501 cttcagcccc tgcttctttg gcacctttaa gtgcaacttt acacattgtg tcattatttc
    94561 cattttttgt tccaaaagaa atacctagta ttttcatttt caactctccc tctttagtat
    94621 ttatttaatc ttctttcatt tttaatatat agaatccatc atctaaagca tctatgatga
    94681 tgtagcctct atcatcaacg ataagatctt ctgttactgc caagcgtggt cctgggaatc
    94741 ctgggaaata agattcttct ggtgttttat ttggatttgg tggtataaaa tatgctagct
    94801 ctttgatata atatgggtct gatacatcat aaacccttag ccctgcatgg aaataacagc
    94861 aatatactct atctcctctt tgctctaacc atggcttatt atccattggt tcatgaagat
    94921 tatgtgggcc aaatggccct ggttttccta atcccgcaac attaaagtta ggataaggga
    94981 aatcttttgg aacttcagga tatggaaatt gagcaattaa tgttggtttt gttgggtcac
    95041 taacatcaac catatgtata ttattcatag cttgaacatc tgtaatgtta tctggtttaa
    95101 agaactggaa tctttctccc tcattttgaa caacgactaa atctcttcct ggcaatggta
    95161 atgctgtatg agttcttgca cctgcaagtc tactagaaaa tgcaggcata aatggcaatt
    95221 cacctaagca tcttggtctt gttaaatctt caacatctaa tacaactaaa ccagctcctc
    95281 cataaccaca atatgctttt ccgtctctta caaatggagg tccatgaagc catcctttat
    95341 ccataaattc tgggcaatga ggtgctcctg catcaaaagt tctatttgga tatccatttg
    95401 catattggtc tggtctccac catttaccta tttccactgg attagtagga tttattatat
    95461 ctatgaccct ataaatcaga ccttcaaagc caacacaatc acttgataaa tgtacatatc
    95521 ttccaccatt gtacatgaat ctatgaacac ccattacatg ctttaagcca caatcccaat
    95581 atcctaaaaa cttaggattt aaagggtctt cttttaaact atatattcta attcctgctt
    95641 cacacttaat atttgctaat ttagcttggt caacaagtgc tcctggtcca cttccacaac
    95701 tcattgctac tatcattaaa tcatctgcta tttgaatttt gggagttgtt gttgtaggat
    95761 actctttagg gtctaacatt tgaaaatgtt ttataaattg tggattataa gggtctgtaa
    95821 tatcgctaat cattactcca ttttttttat ttcctccaaa acagcatcca tataaatagt
    95881 atttttcatc tcttttgtac agagccattt gaaacattcc acaagttcca tctaagttat
    95941 taaaggaaca aacttcaaga tttttaatat atccgttatt tccgttgcct tttgcataaa
    96001 atttatcttc cattttttct cccttcttat ttaaagtatt atcaattgat atactttcat
    96061 tttatgagac aaacttactt aaatccaata tcgttttcat tggaatatat aagttattct
    96121 tattaataaa tttataaaat ctaatgtaaa gatatactta aaacatatat ttttatacaa
    96181 atattttcta atattcttta aaagtaaatt ttcttatact ataataagct ttaattatag
    96241 ataaataagg tttacaaaca atcaagttta aataggggtg attatttgaa tactaaacaa
    96301 ttagaatatt ttatatctgt agcagaaaat ctaagtttta ccaaaacagc agaaaaattt
    96361 tatatttctc aaactgctgt tacacagcaa ataaaagctt tagaagaaca aataaatgta
    96421 actctattta caagaagtaa acgtcatgtt gaactaacac cagctggaaa agttttttta
    96481 tctgaggcac gtactataat aaaaaatatc aatgatgcta ttgcaaaaac acaacaattt
    96541 gcacatggtt tttttggaac tttgagcatt ggaaccttaa taggatatga aaaaaacaaa
    96601 cttcaacaat atttaaaaga attttctaat acatacccta atatatctat ggatatttgt
    96661 actaatgaaa taaccgaact tttaaactta gtaaaaaata attctatgga cctcgctttt
    96721 gttattaatc cagaaaatca accattaaaa gattttgaat ataaaactgt agaaagatat
    96781 tctttggtag ctcttttacc tcctggtcat ccactttaca atgaggattc tatcgattta
    96841 attgaattac aacatgataa atttattttt gtaaaggaaa caggggatga gtatggacaa
    96901 aagtcaatga tacagaatag atatcgtgaa gcagggtttg tacctaatgt ggtacaacgt
    96961 tcaaataatc ttaatactat tgaatcattg gtatcttcta acatgggaat atccatttta
    97021 ccttcatttt gtgttacaga tacaatgata gaacgtgata ttgcaatagt acctataaaa
    97081 gaagtagaaa atagaattga agttgtagtt gtatggaata aaaaaaatac aaatccagca
    97141 ttagaaaagt tcatttctat aatataaaat taatcaatat taacgataaa aatagcatta
    97201 accatttttt ctatagttaa tgctattttc tactatttta ttatttaact tttaatttaa
    97261 tatttataat cattaaaaat aactctgttt aacaaatata agcaagtcaa aaatgtgtct
    97321 aaaaaagata aaaattttat tatatacaaa tgtattatct caatatatct attttttcat
    97381 tattcatcag tctaagtaca tgacctgtgc ttactaaaga attatcccca taagttgtat
    97441 gagctaacac cgaactagca accccaaact caactatatc ttcactcttc atattttcca
    97501 aatatgaata tataattcct gctacatatc catctccggc accaaccctg tcatatattt
    97561 ctagcttata ctccctactt tcaaaataac catcatcatt tgatatatat ccctttataa
    97621 atctattatt catatcatca aatcttctca tagttccagc tacaatatct atatcatact
    97681 cttttttaat caattctgaa ctagatttta tatttagact atctatatta agtatcttat
    97741 ttatatctct ataactagca aacagcccat gacaatatgg tagtattttc ttataatcat
    97801 ttactaaatc atcataagtc ctttctggat ttaatgattg tctaaaatta aaatcaaaga
    97861 atacttttat ccccttttca taagattttc tagctagttc taaagcaatc tctttaactg
    97921 aatctgtaag ttgcatagca ataccacaaa tatggactat atccatttct tctaaacatt
    97981 tatcaatatc ataatcttgt aatttactct cacaaaatga actatttaac ctattcaaat
    98041 aagtcacttc agaaggtctt tctccatacc cattttcaag aaaatacact cctatatgat
    98101 tccctccata cgtgataaag tcatctttta ctccaagctt tcttatattt gcacttgatg
    98161 ctttacctac attattatta ggcaactttg tcaacatata ggtattgtat ccaaagtttt
    98221 taagtccaga taatatattt aatcccgtgc ctgtagttat ataatttagt tcattggttt
    98281 gtgttaagaa cttgtagtca ggtactgaaa gtctcatcat tatttcacca aaagctaata
    98341 tattcataaa tctatcccaa taattctttc attattttat aaagtactcc tatatcttcc
    98401 actttcgttt cacctgtttc tttatcaatt attgatgtat aaacatgagg tataactttt
    98461 tctacaccag catcaagtgc aatttgaact atctctttga agttatctaa gtctataccc
    98521 cctgttggtt ctaaataaaa attatgcttt gcacaagctt ttgcaacttc tatatattca
    98581 tcctttgttt taagccctcc cattggaaaa aacttaattg agcttcctcc catatctttc
    98641 atcatagcta ttgctgtttc tataggaact ataccatctt tttcttttga acttaatgga
    98701 cctgtggata tttttacaaa tcctggttta ccagttggag aaactaatcc atttattata
    98761 ctatcatttt gaccaagcaa tgctctagac gtagccacac ctgtaaacac ttgatttata
    98821 tgttgtggct gaagttcttt agaaatctga gataccatat ttgactgatt tgggtctcca
    98881 gctccaagcc ccacagatat tgcattatct atttcctttg agtatttttt catatcttca
    98941 atagctgctt ctacagtgct ataattcttt gatagtattc ctatcaatac atgcccgtca
    99001 caagcatcat atacttcttt agcatttttt atgcttcctg caagaacatt taaacaaact
    99061 ctatttttat aatattgtgg tatacaattc atatttatcc cctccattgg taaaatttaa
    99121 tttattaaat cattataatg tcacttactc tacactctaa ctttctacta tattttttat
    99181 cctattataa atagtatcta aatcacttcc agttacactt cttatatcaa tctcaatctt
    99241 gccttcatta gccttatagt ctctagtgta tatagctatc tctccacttc taagttcatt
    99301 tataatttgt tgtgttgact tatttattat atcttcatta aagtcaattt ctccacgaag
    99361 tatttctcta cctgctgaat ccctagttat actagcactc actcccttta tagtatttat
    99421 cttgtctata aatggattta gcttatcctc catttctttt aaagttactt tatcattact
    99481 tatatatctc tcaattgcac atgttagacc tacaatattt tcttttccta ttttcatagc
    99541 tcttcctata ccctttgatt gaagctttac attatctatg tattttttct tacctattac
    99601 taaccctgag ctaggaccct ctatagcctt agcaccactg tatatcacta ggtctgctcc
    99661 caattcataa tatacattta aatcttcttc tgctgctgca tctactatca aaggtaaatt
    99721 atattcttta gcaacttgta ctgcatctaa tacacttagc atactctttt gaacacaatg
    99781 atgagattta atatacataa ttgctgctgt attttcattt atctctctta ttatatgttc
    99841 cttgttacac atattagcat aaccggcctc aacaacttct cctcctccaa gtcttatcat
    99901 tacttctact ggaactccat aatcaacatt atgtcccttt ggaattatta tttccctttt
    99961 aacttgtttc ttaggattat ttacattgta aactagactc atatcatctt ttgctatcat
   100021 tgctcccaca ctctgtgcaa tcccagcaga tgcactagaa actattagtg cactttcaca
   100081 ccctaataaa tttgctatat attcacctgt tttatttata agttcttcta ttataaagaa
   100141 atttttacac ccttcaccta ttgcttcaat aacttcctta tctactgttg atactcctag
   100201 tatagtcatt ttgcctgaag catttataac acgtcttaca gagtattttt caaatatact
   100261 actcatacaa tagtttctcc cttctactca ttctctccta tagacttacc tatatttaaa
   100321 tattctccat tgactactac tgctcttggc tttatagacg tacttgtgat tactgactta
   100381 ttcaaagaat cttgaagttc tttttcttca ttaaccacat caaatatagt taaatcagca
   100441 tcatatcctt cttttattaa acctttattt tttaaactta ttgcatctgc tgcattttta
   100501 gtaactttat ctattatatc ttcaagtgaa tagcccatat atataaactt ttccattgtt
   100561 gtagatagat tatacactgg accatttatt ctatttttaa tatatatatc tgtacttata
   100621 gtgtctggaa aaattcctgc atccttagat ttcattgcaa tatccatact aaaactttcg
   100681 gttccatgac ctacatcaag gattatacct ctttctctag cttctatgat ttctttttta
   100741 acctcattgc ctctaagtat tccatttggc tttccattat atatatgggt taatatatct
   100801 cctttttcca tatagtcaaa tatatcctct atcgttggag gagaactccc aaagtgaacc
   100861 atcataggta gattaagttc attttttatt cttttagcta cttttaaagg ttcaacatca
   100921 tttgaaatta caacactttt actcattcta gctttgattc caacaacaaa atctttgtat
   100981 tttttaactg ctcttctaag ttcatattca tcaatattca tcatacttga aagttcatct
   101041 tgagatgtta ttccctgctt agcaatattt attaaagcat atacatttgt tttatatttt
   101101 ttagtatctt cataaaattt acctatatct aaagctcctg ttgttcctgc atctactaca
   101161 gtagtaacac cgctttttat tccaacctca tctggataat ccttataaag gtctagtctt
   101221 tcgtagcagt gcgtatgtat atctatccaa ccagcactaa taaatttttc tccatctagg
   101281 tttataattt gatttgcctg atacttagaa tcatctatct gattttttac ttctattatt
   101341 ttatcgtcta atatagctat atcaattata cttttatcta ctgtttttcc acattttatt
   101401 aatatgtcta tcttcacttt actctccctc taaaataagt ttaaatttac tccaaggttc
   101461 aataaagtct aaaagtatta tttcgtcttc ctttattcta cccaccttat tttttctttc
   101521 atctgcacaa tcttgaagta tcaactgtaa ttccccttta tactttccaa agtcatcatt
   101581 accaatcact acatctcctc ttttaaagat ggtcgtatta tcatgcttag ggaaattttc
   101641 tttagcatat ttttttctta cttctgtaga ccttgctact tggttggtta tatcccctct
   101701 tctaaagtgt tgctcatttg ccattattgt cttttctact tcagaagttt tttcttcagt
   101761 tactacatta aatacaactt gatatttatt tacttcagac attcttttta attcatcttc
   101821 acttgcatat gcattcccta caattacatc atcaatcaat cctgttgcga ataagtgctt
   101881 ggttgctgta gcaatatcta agtttctatg catttcaagc gtacacagcc catcatttat
   101941 attccaaggc cctattgttg cgtattttga attaacaaaa gcagcagttc ttattccata
   102001 ctttttaaat ctatttgaac atcttacaaa aaaatcatat ggcaagcctg tacccctttg
   102061 aggataaaaa ttgtgacaac catatatatt atttacattt ggcttgtaag taattatatt
   102121 atccaagtat gctacatcat tactcatatt tagttccact tttaaatcat atggattgaa
   102181 agaaatcata gcttctttac ttccatcata tccatagtca agccttattc cactagcatt
   102241 taactcacta aaaaatgtta aatcatcata agatatttgt aatatatcaa atatgtttgg
   102301 agctatatca aggattactt caaatcctaa ttctcttgca taggttataa tctctttaaa
   102361 atgtttttta acttcttcct taggtcttgt aattgaaagc atgcacataa atattctttt
   102421 aaatccgtat tttgaagcca tttttatata tgccttatca tcttccatgt tactatgctc
   102481 tggatatact gatattccta atcttctttc catctttctc ctcctcaaat tacattattt
   102541 aaaatatata aaattaaagg caaaggtcat tcctcctacc ttcaccctta ataacttata
   102601 agctttttct atattttata tagtacaaaa cctctatatc tatgtatttt tataaatttt
   102661 cactcatttc ttcttgttct ctttgtaatt gttgtttttc aaaaactttg aagaatggat
   102721 aataaacagc aaatgatatc acaaagttga ttaatactaa gatacctgct agtatactcc
   102781 agttagtact cattactgct gctattggtg ctggcattgc aaatggtaat cttgctacca
   102841 tcataggtat aacccctgta atagtaagaa catatgatag aattgtcatt attataggtc
   102901 caattataaa tggtatccct agtattggat tcataactat tggtgctcca aatattatag
   102961 gttcatttat gttgaataac cctggtaaaa atcctaatct acctaaactt tttagatatt
   103021 gtgacttaga aaacataaac attacaacta atgcaagagt agcccctgct ccccctatcc
   103081 atacatacca ctgtaaaaat tgttctgtaa atatgtttgg cattgcatga gctgatactc
   103141 cttctgtgaa tgcagttata ttttctgcta tagacatgtc ccatataggt cttattactg
   103201 gtcccattat agctggacca tgtattccaa gtacccagaa taaagttatt aggaatactg
   103261 tcagtaaccc accacctaaa ctatttcctg ataagaatcc ttttaaaggt gataacatag
   103321 cgcttagtgc aacacttata tcaaatccta gaatatgtct tattacccag aataacatta
   103381 aaattactgc tgtcggtaat aatgcagtaa atgaatttga aacctctact ggaactcctg
   103441 ctggcatctt aattgtaata ttcttttcct tcataaaacg atatatttca actgtaatta
   103501 atgatgttac gatagctcca aataatgatg gcgaattaag ttttgccata tccatccatc
   103561 taccagcttc tataactcca cctactggtt caactacttg agttggaact attgtagaaa
   103621 ctaaaaatgc cataactgca agcataccaa cacctgttgt atctaaatcg tagcttttag
   103681 caagtgatga tgctatccca aaagtagcat atagagataa aaatcctaca gtatatctaa
   103741 atggtatatc taatattgct ttaaatggag ctataaaatc catataagca tcaataggta
   103801 tgtttaataa tattgtgaaa aatgacccca ctattgttag tggtaatgtt gctattatac
   103861 ctgctcttac agctctcata tgtctctgat tacttatctt cgctgctaca ggcataatct
   103921 tgcgctctaa aaaacttgcg aatttttcca tagttatccc cctgtattat tgatattatc
   103981 ctttatttat aatgcaataa cgatttcata acataaacta atttttatgt aattgataat
   104041 atcacttgtt tattaaaaat attataacat tataatgttt ggttgtaaac attataatgt
   104101 tataatattt tttattttta caactaaaca aaaatcctga gcatattatc atttcaataa
   104161 actcaggatt cttattatat ttcgtattta attacatagt tttgtacttc tgtattatat
   104221 cttgcaaatg atagctcaac tatattatca ttctcatcat aggtctttct ttttcttcct
   104281 aataatatgt ctttagctag atttaaagcc tttgatacct ctagttctga ttcttctata
   104341 aaaaattcat cttcaaatct agttatattt atatttctcc tatataagta catatataaa
   104401 gaactttcat tattaaaact ttcaacagtt agattttcat caaaaggaat ataatgagta
   104461 aaaaatatat atggcttact atctaaataa tacattctag taatcttgct acatttttct
   104521 ccaaatatac taaatacttg tgaatttgta tcatttatta ttttttcaat tgaaatagtc
   104581 tctttagata acttatgacc tttagataaa agtatacttg aaaaagactc tgcttttgat
   104641 agcttattaa aaaggctatt acttattact tttgtccctt ttccactttt tttctctaca
   104701 tatccttctg attctaatat ctcaatagct tttctaatag taattttact gactccaaac
   104761 tcttgctcta actccctttc tgttggaata ttttcatcaa ttttatattc gttatttaat
   104821 attttttgct ttaatatatc tacaacttgt atatataatg gttgatttct taacatgatt
   104881 cacctcttaa attatatgtt ataatattat aacatataat cttatattat taataataaa
   104941 tatttattaa ctttaaacta aatataaaaa gagtcctcaa aataatccta atgtattact
   105001 cactaaatat tgaatcaata atctaacaat tagtgtgcta cacataatgt atcttttaag
   105061 aactctctta atttattatc tttaattttt atttatcttg taatttcaaa tgtaaatcaa
   105121 cgatttcctc agctaactgt tgaaaattca tgccattcat taagtggtcc tgtgcatgta
   105181 taagtatgac acttatttca gtcctgtttc cactagcttc gttttgtatt aattctgttt
   105241 gatatctatg tgctttattt ataacttccc tagactcttt taataattct tttgcttttt
   105301 ctatatttcc attcttagcc tcttttattg cttcaaaagc taatccttta ccttcacctg
   105361 cataacctat tatattaaaa gatatttcta tagtcttttc atccatcctt tgattctccc
   105421 aatttatata ttaaaaatac attataattt atattactta gtgttgttaa gttctatcgc
   105481 tctatttaaa acagcttctc cattaactgt tccatagtgc atcatattta taacttctac
   105541 tggtatatta tatggcttag caatttcttg agccttaggt aatacatatc taacttgtgg
   105601 tcctagtaat aatacatcac atttttctat ttcattttgt atagttgatt ctggtattgc
   105661 ccaaatttgc gactctatac cattttcttt agctgcactt tccattttag taactaataa
   105721 acttgtagac attcctgctg aacaggccaa cattattttt atcatatatt ttcctccaaa
   105781 tttttattaa caaccatata aacattataa tgttataata ttttatttaa ttctacctta
   105841 aatgcaatat actttcaata cttttttgtt attttaatat tattaagtgt caaattaaca
   105901 aaaaccgtat catttattta tgatacggtt ctccattatt tatcctataa gccctataaa
   105961 tctgttctaa caatatcaat ctcatcatct gatgaggaaa agtcatctta gaaaaggata
   106021 acctataatc agcccttcct aaaacctcat cagaaagccc taaagaacct cctattataa
   106081 aacagagact actattacct ctaactgcta aatcactcat agtcttagca agctcttcag
   106141 aggataaacc cttaccatca atagccaagg ctataacata actattatgc tttatcttcc
   106201 ctaaaatttt ctttccttct ttgtctttta taatttccat ttccttaaca ctcaaattct
   106261 ctggagcttt ttcatcatcc aactctataa tttctaactt acaatactta gaaagccttt
   106321 tcttaaactc atcaatacct aattttaaat atttttcttt aattttacct actactacta
   106381 tacttatatt catatatttc tcctaaactt aattttatta caaatctatg cattactaga
   106441 atttacaagc tcttataaaa ttatatctct ctttcttgat ttgcatattc tacaaactct
   106501 tcaaaaggta ttgctttgct ataataatat ccttgatata tttcacatcc taaaccatat
   106561 aacttatccc tttggtctat attttcaaca tactcaacaa ctatatcaaa atctaaattt
   106621 tttgaaagat ttacaatagt cattataatt tcactacttc ttttatttgt aagtatctct
   106681 ttaactaatg aaccatccaa tttaactata tcaaagttat tattttgaag atatataaga
   106741 gagctatgcc ccatcccaaa atcatccata attaacttta ttcccaagtt atgtatcgca
   106801 ttgatacgtt caataattat ttgtgaacct gataatgcaa tttgctctgt tatttctata
   106861 cctaacatat taggatttat atcattacta ctaatgatat tttttatttg ctctggtaac
   106921 ttagggtcat caagttggtc tggagatata tttacagaga acttaacagg atttctcaat
   106981 agcttttcac tcttctttaa atcaatacat gctttattaa taatatactc tccaagctca
   107041 tctaagaacc cttcttcttt agccaaaatt ataactagtg gtggataaat gaaccctcct
   107101 attgaatgtt tccatctaag taatccctct gctcccacaa catttccatt ataattgact
   107161 tgtggttgat aaaaaagctc tatttctcct cttttcatag caaacttcaa gtctgatgcc
   107221 aacatttttg aaattgaacc tattttacca ttatggttta gaagattagg ctgttcacct
   107281 gttaattcat acctttttaa taagtttgtt aaattttcta tattattttt aaacatatat
   107341 gtatatctat tttgcgacat ttttataaac ggaatataaa tcataacacc aacacataaa
   107401 ttaaatactt gcaacaaact acctcttatt gaacctgtag acatatatcc acttaaaaat
   107461 ataggtgagg tccattctac agctgaaact gtacatggta caatacctgt agacatagcc
   107521 acataacttg taacggttaa gattatagga gtaattacaa aaggtacaaa cataatatag
   107581 ttaaaaacaa ttggtatccc gaaaactagc atctcattga tattaaaaag agctggtatt
   107641 gaagcaattt tagctaactt tcttacattt atacgttttt cactaagaaa aattgcaatt
   107701 actaaacata gtaaagagcc acatcctccc aataaaacca ttgtatcaaa aaaggtctta
   107761 gtaaaaattt ctgttggtaa ttgattatta ttaactaaat ttatgttaat tgccatacta
   107821 ttttcaaata aattttttgc gacggtatct aatacattac taccatgaat cccaaaaaac
   107881 cacataaagt gcattaaaaa aataaacaac agagcactca taaggtttgt tcccatttta
   107941 ttaaaaacat ttgaaaataa attataaaat atatcttgaa agtttgaact gccaattaga
   108001 cttatcatta ccactctaaa aatagaaaac aaaaatacta ctattatgaa aggaactata
   108061 gccgaaacta ccatattaaa gtctgcatca gccccttctg tatgaaactt tacacttgta
   108121 acaaaagatt ctgtaagttt tacaaacaat acagaagatg tcatagaaac aattatagat
   108181 gtaaataacc actttgtttt aaatatttct atataagaat taagctcatt accatgtgaa
   108241 aatactaaaa aagagcacat tgcaactata ggaacaagta ctgtatactt gctcccatat
   108301 atttttccat aactatagct tattgttaat aatattatta atgaaataat tcctaaagta
   108361 gaatcattta taaagttaag aatatttgta acctctccat taaacaagcc tgataaatat
   108421 tcttgataag cctttattgg aagattcaaa attacaagag cagttgaacc agtcataata
   108481 gcaggtatcg ctaaaatcat accctgcttt atagagtata aaattttatt atcctcaaca
   108541 ttttcaaaat ttctctttag caaagttatt cacctctact tcatctcata aacattagaa
   108601 acatcatttc gtgatagtac atctagtttt acatcttgtc caactactat atcatttgat
   108661 gctaatactc cttttgaagt ctcatacgct aactcaggaa aattattttc tttgcttaaa
   108721 tgtgctaata atatagattc tgtaccttca ttaataagtt caacgcagaa attagctgca
   108781 tcttcattgg ataaatgacc agtacttgac attactcttt tctttaaagc atatgtatat
   108841 gaacccatca taagcatatt agggtcataa tttgattcca atactactaa tttagattta
   108901 tatagatgtt tttttatatt ttgagttata catcctatat cagtagctat agacattttt
   108961 tcatcactct ctgtataaaa attatatcca actgggtcag acgcatcatg ttctattgaa
   109021 aaaggtctta ctatgatatc acctaatgag taggttttat cattttcaaa tactttcata
   109081 tttttatctt tgatgtcacc taatttgtcc ttcatagaac accatgtttt tatattagca
   109141 aatactggta tatcaaactt tcttgataat atacctgctc cttttatatg gtcaacatgc
   109201 tcatgtgtta taaatattcc ttttaattta tctgcatcta caccaatgtc tttaagacct
   109261 gtagttattc tcttgccact taatcctgca tctactagta tattagtatt tttataccct
   109321 atatagtggc aattaccact actaccactc cctactgaac aatactttag cattccttca
   109381 cctctttttc tgccttataa attatattat accaaaaaaa cagagtatta aataaaattt
   109441 aatactctgc acaaaattta cttacattca ctatttactt acattcactt ataatcttat
   109501 ttatatctac acctttacta ttccatagtt ccacaaaagc tcttccatta gcatttttat
   109561 gcttatattt attatagtac tcatttaaag tctcaaagaa tactttatct ccaacttctt
   109621 ttcttatttc attaaatgct attgcgcctt ttgtataaac attcaagctg tattcagtag
   109681 aatttttata ctcatttgct ggcttaaata tattttcact caaataactt tttgtctgta
   109741 tctccatagt ttttataagc ttgtttgcca tatctttacc atacttttgt tcaaaataaa
   109801 ctattgtaga atattcagta agtgcttcat ctaaccaggg ttcacttatt tcatcatttc
   109861 caacagcaga ataccaccat tgatgtgctg tctcatgggc aataacatat tctagtaaaa
   109921 attcattttt ttcattatat aaactttggt ctatcataac aagcataggg tattccatcc
   109981 cccctataaa aaagtcactt gctacaacag aaaattcttt gtaaggatac tttccaaata
   110041 attcactaaa tatatttatt gaatcttttg ccacttcagt tgctttttta gaaagctttt
   110101 tatttaaatt atatgtattg atagctactc cctttgaatc tactttgttt acatcaaatt
   110161 tactacttag tataaatgca aaatctctaa cgttttcagc ttctatttca tatagcattt
   110221 tcttattatc atgtttatca tcaataagtt ttcctgtatg agcaatttta tatttatttg
   110281 gaatcaatag tttcacatga aaatcgctag tctcactata aaatgggtcg ccaatagttt
   110341 cataactctt taaattccat cccctttcat catttacaca agctatagga aaccaattag
   110401 taacatttat agtattttct ccatatccaa atcttccaat tgaatttggt atttttacgt
   110461 tatattttat atctaatgac attctttcat ttggttttaa ctctttccct aattctattt
   110521 ctaatatgtc atttttgtct cctttaattt tatactccat tttactatta ttatttaata
   110581 tattctttat atctatatat ccttcgttaa atccattagg ataagccctt gtcatttcac
   110641 ttttttcaaa aggagcaaaa tctttcttgg aaaaagcatt cggatatata tggaaatata
   110701 ttttatctat gtttgatttt gtattattta tgtagtcaac attctgattg cacattaacc
   110761 tcttagtctc atcatcaaat ataacatcca tattatactg atttattttt gaattagttt
   110821 tttctttgta tgtttctaaa ctgtcatcct tttctataaa gcaacctatt attaatacca
   110881 taaatagaat cgctactgat aatgttcttc ttactttttg gttgaatttt ataaccaaaa
   110941 tatctcctcc ttttcaaaat gaatactttt agaaaatatt tacatgctaa tcttgtgacc
   111001 ttttatttgt ttacagacaa atataatata aaaaatgata taatttaatc tgaggtgata
   111061 aaatgttttt taaagaaagc aatgaaatag atttaggtga aatcactatt cccaatatct
   111121 ttatagatat atttatgcca atggcggacg ggttatacgt aaaagtttat cttttaggat
   111181 atagacaagc atgtgatatt acttctaatc ctaagttcga caataattca atagccaaaa
   111241 acctaaatat accattgtct gatgtgttat ctgcttggaa attctgggaa gaaaagaaga
   111301 ttataaaaat acatgacaat gaagaatatg ataattttaa ttattcaata gaatttttag
   111361 atttaaaaaa tttctatatt gagaatatat taagcaataa ttcatctata aaatctaata
   111421 cagataaagt tgtatctact tctgaaaatc caagtattag aaaaatgttt aattctataa
   111481 ataaaatagt tgggcgatat ctcgacccaa gtgaaaagat gagtattatg gatataatga
   111541 ataaatacaa tatgagcccc gatatgatac tttgcgcata tgaatacgtc aaagataaaa
   111601 ctggtacatc aaagccagtt aaatacattg aaggcattat tagaaattgg tatgattcaa
   111661 atttatatac gccaaaagat gttgaagaaa gctttttggt aagaagtgaa cgatatattt
   111721 tatataaaac gattttcaat gaattgggat tttcaagaca accatcaaaa tcagaaaaag
   111781 aacttatgga cacctggttt gataaattta atatggatat agatttgata ataaatgcat
   111841 gttctaagtc taagaatatt tcaaacccaa gtatatctta tataaatggt ataattaaaa
   111901 attggaatga aaaaaatata aaaaatttaa atgatttaaa gcaaaaagag gaagaacgta
   111961 tagttaagga gaatattaat aagaagcaga ttaatactac tcaaaacaac aatacttaca
   112021 aaaaaactaa gtttcataat ttcaacgaaa cattcactca gtatacctct gatgagctcg
   112081 atgagattat taaaaaaagt caaaaagaaa agtttaagta ggtgattaaa tgaatgagga
   112141 taaaataaga aaaatacttg ctaaatatgc taagagaaga gatgataatg aactcttatt
   112201 agaacataga aaaaatgagg tatataatag aatccctgag ataaaatcta tagatgatga
   112261 aatttctaaa ataggtctca gtttagctaa gatagtactt ttaaatccta agtctaaaga
   112321 tgaaattgta aagaagacta aagagaatat agaatcttta aaagtaaaga aagaaagact
   112381 tttagctgaa agtaacatac ctcttgatta cttggaaata aagtttcaat gtatttcttg
   112441 taaagataaa ggatttttac ctaatggaga aaaatgttct tgcctcaaac aagaaattgt
   112501 aaatgaagct tataaaatgt ctaatttaga taggatttta agtcaggaaa atttttcgaa
   112561 ttttaacttg aatatatttt ctcctaagaa aggctctgat ggtgaaatat ctcctagaga
   112621 aaatatgcta aataatttaa gtatctgcga aaattttgtt catgatttta agaaggataa
   112681 tagtgaaaat ctactgtttt atggttctac tggactagga aagacctata tgtgcaattg
   112741 tattgcaaag gaattgttag ataaaggcaa tgttgtaatc tatcaaactt cttttagaat
   112801 tttagatatt cttgaagatt ataaatttag aagagacaca aataatcaaa taagtgaaga
   112861 taattataaa aacttgtttg attgtgattt attaataata gatgaccttg gaactgaact
   112921 taataattct tttactagtg gagaaatctt caatattgta aatacaagac ttgttgctgg
   112981 taaaaaaatc attatttcaa ccaacttaac accatctcaa ataggaaata cttacactca
   113041 aagaactctc tctagaatat tagataagtt taggatttta gaatttactg gagatgattt
   113101 gagatgggaa agatttaaat aaaatagccc ttaaaaaaca tttttttatt tttaaataga
   113161 gaggtaagag caaacttgct tctctgttta aaacttatat cacataaatt aaaacatact
   113221 ttttattttt ctatttacat atctaatgta ccttaatcta acaaatcatt tacattctta
   113281 gtagtctata tttattgata ctataaatta aatttgctat attacataat attatgctag
   113341 aatgattcta aattttatat ttaaaactat cacattgcaa gtaattcaaa attttgttgt
   113401 atgtttaatt tcatttttaa tacaataaaa atgaaattaa aaaaagatac ttaaaagtat
   113461 cctgtaacat agaaaattat attaatttga atttatgtac tttgtggagc tggtgatagg
   113521 aatcgaacct acaacctgct gattacaagt cagctgctct accgttgagc cacaccagca
   113581 tataatctag tatttatctc taattcaaaa tttggtggga ctaacagggc tcgaacctgt
   113641 gaccccctgc ttgtaaggca ggtgctctcc cagctgagct atagtcccat actggtgact
   113701 cgtaggggaa ttgaacccct gttaccgccg tgaaagggcg gtgtcttaac ctcttgacca
   113761 acgagccata ttttggtgat ctatccgcga ctcgaacgcg ggacaccctg attaaaagtc
   113821 aggtgctcta ccgactgagc taatagacca cattttttcg acttttttcg tcgtttcttt
   113881 cactcacaag ttatattata gcgtctatat aatttttagt caatagtttt ttttactttt
   113941 tttagaatat aattaaaatc atctttagcc atttattttc aacaaaattc tttttaaaaa
   114001 acctatatgt atctacataa attcaacttt aatttcagtt agaatatgta taagtagctt
   114061 taacttaata aaaaatcaat gtaagtcaaa tataaaagag catctctaat aactataaac
   114121 attatcttga gatactcttc ttcaactatt ttaaattatt taattgataa aatattaagc
   114181 aaatatattt cttcttatta tagtttgagc tctatttgga ccaacagaaa ccatatctac
   114241 acttactcca actagttctt ctatttttgc tacatatttc tttgcatttt ctggaaggtc
   114301 atcaaagtta tctatttgag ttatatcttc attccatcca tctaattctt catatacagg
   114361 ttcacatttt gctaaatcat ctaatgaagc tgggaaatcc gttattatct tatcgcccat
   114421 tttataagac gtacaaactt ttatcttatc aaatccagtt aatacatcaa gtaacataaa
   114481 tgaaatacta gtcaatccat taactctagc tgcatactta actataactg catcaaacca
   114541 cccacatctt cttggtctac cagtagttac cccaaattca tgtccttgtt ctcttatctt
   114601 atctccagtt tcatttattt gctctgtaac aaacggtcct tctccaactc ttgtagtata
   114661 tgcttttact ataccaacaa cgtcttttat catatttggc cctatacctg caccaattgc
   114721 aaatccacca gatgttggat gagaagatgt aacaaatgga taagttccta aatctaaatc
   114781 taataaagtc ccttgtgctc cttcaaacaa tactttttta cctgctctta ctgcatcata
   114841 tacaataaca gacgtatctg ccacatattt tcttatttgc tctgcatatc ctagatattc
   114901 gttatatata gtttcaaaat caaataattc ttcttttcca tatatatttt taactatttc
   114961 atttttagca tctatttgag cttttaattt tatagcaaat ttatctttat ccattaagtc
   115021 acatattcta ataccagatc tctctgtttt atccatataa caaggtccaa tacctttttt
   115081 tgttgtacct atctttaaat cgcctctggc ttcttctgac aatgcatcta gttctttatg
   115141 atatgggaat atgacatgtg ctctatcact tatttttata ttttctgtac ttatattatc
   115201 cgttttaaac atttccaatt cttctaaaaa tcctttaggg tcaaacacta ttccatttcc
   115261 gattatattc actgtatttg gatttaaaac tccagatgga attagatgta atgcgtattt
   115321 tttaccttct acaactaatg tatgtcctgc attatttcca ccttgccctc ttactactac
   115381 atctgcttga gtagcaagat aatctataac tttaccttta ccttcatctc cccattgaga
   115441 accaacaatt gcaactgttt tcatgtaatt cacctctata ttttatatac tctcgaacac
   115501 tttacttact tattctatca aacattcgta tttttttcaa cttttttagt attctccaat
   115561 atttaacata tattcttcta tttttgaaaa ctcttctttc tctattattt ctttttcata
   115621 ttttataact ttttccataa atttatccac atctaaaagt ttttctaatt tacatatgtt
   115681 aattatattt ccaaagtttg tattagtcat gtttatatga tactgattat ccacattatt
   115741 agcataaaca acaatagatt ctcttaaatt attgtcaatt actctaaata agtttatttc
   115801 atcaagtact ttaattatat tgggatatat atattttaag cttatttttt ccatattatt
   115861 cctcctaata attaatattt atacacagat aaagcaagcc aaaagcttgc tttatctact
   115921 tattcacact tatcaacagg ccatctgtgg atagtgtgga tagtttttta gctaaatttc
   115981 aatgtttgga catatttagt gacatgtatc cacatttttc ctgtagaaag aaaggacgtt
   116041 ctgtggatat tcgttagatt ataggtctct caacttatcc ccaaatcttt gaacttcacc
   116101 aagccaaaca agttccacag aaccagtttc accgtgtcta ttttttgcta ttattacttc
   116161 tcctatattt ttactctcag aatcagcatg ataatattcg tccctgtata agaacataac
   116221 tatatctgca tcctgttcta ttgctccaga ctctcttaaa tcagataaca taggtctatg
   116281 gtctgctctt tgttctggtg cacgtgataa ctgagatagt gctactacag gacagtttaa
   116341 ttcttttgct aatattttta gtgaccttga tatcttagat atctcttgtt gtctgctttc
   116401 attattacct tcaccttcca taagttgaag ataatcaata agcactaaat ctagtccttt
   116461 ttctattttt aactttctac actttgacct tagttctgat atttttatac caggagtatc
   116521 atctatgtgt attttggcat ctgataatac tgccatagca tctataattc taggccaatc
   116581 attatcatta agtgttccag tctttatttt ttttaattct acactagatt gtgaagataa
   116641 catacgttgt actaattgtt ccttagacat ctctaaacta aatacagcta cagaggcatc
   116701 accttttaag gctgcatttt gaaccaagtt taaagaaaag gcagttttac ccattgctgg
   116761 tctagctgca attaatatta aatcagtcct ttgaagacca tttatttttt tgtttaaatc
   116821 tttaaaacca gtagttatac cagtgacatc actcttgtta gtgtataatt tttctatcat
   116881 atcataggca tccatcaaaa ctaagtttat agatttaaaa tcatcactag ttttctcctg
   116941 tgatatatca aatatactct tttcagcttg ttctaaaaca tcttcaatct tagttgctcc
   117001 actatatcct agatttatta tttcattaga agcttttata agctttctaa gtacagactt
   117061 ttcttttact atatcagcat agtattttac atttgaagtc gtcggtacta tagtagaaag
   117121 acttgtaata taactgattc ctccaatatc attaagatgc ccttgttttc ttagttcttc
   117181 tgttaatgtt atcaagtcta taggctcacc tttattactt aaagttatca tacattcata
   117241 tattattttg tgagcctctt tatagaaatc atcaggcttt atagtttctg taaccgttat
   117301 tatagcatct ttatctagaa gtatagaacc caatattgat tgttctgatt ctacactatg
   117361 aggaggaatt ctcgtcatat cttccatctt aatcacctct agttattact gtttttcttt
   117421 tacatccact cttattttag tagttacttt ttgatgtatt tttatttcta cgaaagttga
   117481 acctaaagat cttattggtt catctaataa tatttttctt ttatctacat ctatgtcttt
   117541 ttgtttcttt aattgctcag caatttcttt agaagttatt gaaccaaata atcttccacc
   117601 ttctcctgct tttgaatata tttctatatt aatttcttcc atttgcttac ctaataaaac
   117661 tgcttcttca tactcttttt gtgcttttat ttctttagat ttattctttt catttaattc
   117721 ttttattgct acactatctg cttgcacagc catcttttta ggaaataaga aatttcttgc
   117781 atatccatca cttacttctt tcatttctcc ctttttacca gttcctttta cgtcttttaa
   117841 taatataact ttcatctatt cttcctcctc caaatactcc tctattattt tatttaccat
   117901 cttataagct tcttttagag aaacattttt taactgtgct ccagctatat ctatgtgtcc
   117961 cccgcctcct aatttttcca taagtacatg tacatttatt tgtcctaaag acctcgcact
   118021 tataaatata gtatcatctt tttcacctaa tacaaaggaa gcttctactt ctttgatatt
   118081 taataactca tcagcagttt gagctattat aacatttata ctatctatct cagtacttga
   118141 atatgctaaa catattctat tattaattat tttagtactt tgaattattt cagcttttat
   118201 tatgaaatct tttacatcag aattgaagaa tttctttacc tctatagtat ctgctccaac
   118261 ttttctaagg taagaagcag cttcaaaagt tctaacacct gttttgaatg caaagttttt
   118321 agtatctaga cttatacctg ctaaaagccc ttcagctgta agtttattta ttgttacatc
   118381 ttcatccata tactgaacta actctgtaac catttcacac gttgaggata catatatctc
   118441 atggaataaa agcactgcat catttataaa ctctacacct cttctatgat ggtctataac
   118501 tactaccttc tctgatagct ttaacagttc ttcacattca gtataatttg gtctatgagt
   118561 atcaactact acaactaatg tatttttagt gcagttgtca atagcttcct cttttccaat
   118621 aaacaacttt ttatagtaat tattttcatt tattttattt ataaatattt ctatagattc
   118681 atttacagat tgtaaaacta tgtttgcagt tttgttacag gatttacata tatcataaac
   118741 accaactgct gctcccatag catccatatc aggatattta tgtcccatta tataaacttg
   118801 gtcactttgt tgtataacct ctcttaaagc atgacctatt aatctggatt ttactttggt
   118861 tttcttttct acagctttag attttcctcc ataaaacaca aatttatctt ttgtttttac
   118921 aacagcctgg tcaccacctc taccaagtgc taaatcgaga gcacccgtag caagttttag
   118981 gttctcattt aatgtatctc catctatacc aattcctata cttatagtaa caggaagatt
   119041 atttccataa tcaatatgtc ttattgtatc taaaatagaa aacttctcag cttccaattt
   119101 ttttaactct tttttatgca ttaccaagaa gaatttgtct tttgaagttc ttctcaatgc
   119161 accatttgaa tttaattcta aagcagaaag tattttctct acttcaacat taattaaagc
   119221 tctcttatct tctgctgcac tttttaatac ttcatcatat ccatctactt gtattagcat
   119281 cattgcattt ttttcatcat cataattttg ttttactttt aaatattcag tcttgtctat
   119341 ccagtataat atcatcaaat atttaggatt tttttcttga tcatttttta taacattata
   119401 aattattgta tattcttttt ctttatagtt tatttctgtg tacatctctt tattttcatt
   119461 taatactttt cttaaattaa gatttttaac tatatcctct atatttttat caagtaaatc
   119521 tttttgacca atcatatcat aaaactttcc attataccag gatatatttc catcaaattc
   119581 taaaatacat aatggtattg gaagatttat tatggctttt ttagttgttt catctatatc
   119641 taaagataaa ttttgaatat actctgtcca ttcatgacgt ctaatattag tagttctcca
   119701 attgtgaaaa accatatata caaaaataca gaaaaataaa caccctacat acaagttgta
   119761 ataaagcaaa attatactag aaataccaat aacaattata tataaattta tttctggcat
   119821 atttaattta aaggtttgtt tattactcat ttctatcctc ctaagtggat ttatagcttc
   119881 ttacctttct aaagtcaatt atactatcta ccataccaac aaaagatatt cccataaatc
   119941 caaataaaca taaaattatc cctgaaaaaa acataatttt atttggtccc tgtcttatcc
   120001 atttctttaa gaaataaatg caaactgcta taccttgaat tacaaacatt aaattaaaaa
   120061 ctagctgtaa attagtcatt attaattctg tatataattt tgaaccaata atttgaataa
   120121 ataagactaa taaataaagt aagaaagttg tgagtatagc atttcccggt aaataaaaat
   120181 cagcaaactt aggaaatctt atattcatct ttgtaatcct ttttataaaa aatacactca
   120241 aataatatgt gacaaacgct gataacaacc cttgtaaaaa taacatcatt ggtagcatat
   120301 ttgtaaaata acttacaatc tcatctggct tcattttatc aaacacttta agttcagttg
   120361 cagaaaaact atttttttga atatttacaa tttctgatat catcttagaa acttcatcta
   120421 atagattcac atttaaaaat gtctttaata caaaaaaata tacaagcatt gaaagtacaa
   120481 atattatggt tccaccatat atcggttcga atttattact gtcctcttgt tcaaagcttc
   120541 tctttagcat ctttcctatt actatacctg gtaaagaata cattatacat atatttaatg
   120601 cataagaaat gtctgcaaat agaatcagta cacaaaatgt aaccaaaata gatataagag
   120661 aatactttct atcagtaata gcacctataa ttacatatgg aacagctgct aacatactaa
   120721 atattcctag cattggaata taggctatta ctaaagcgat tattatagct aaaactatta
   120781 tagacattgc cttagatagt ctaattttat tattcaattt aatatcactc cctattatcc
   120841 atatgttttt ttaaattaga taaatctcca taccatcttt caacgctatg gtcctcatct
   120901 ataccaattt ttattttttc cttgacttta taatccacat ctctaaaact aattcctaat
   120961 ctctttgcta agagatatgt tatcattatt atatttgcta aagtatcttg aattgcttca
   121021 tctaatggtt ttaccccttt aaacaataaa ttaaacaaat cacttacact cattaatatt
   121081 tctgttttca tccattctat tatctttatg tttctcgtta tctcagaacc tttatctatt
   121141 ttcacgttta caaccctcct taatatataa tattatatca taaataataa tatatttaag
   121201 tatataaaca aaaaaacgag ctttatagct cgcctcattt agatatataa atacatataa
   121261 taaaaaatga gcacaaggct cattttttta gtctaatgta tatggtaaaa gtgctatatt
   121321 tctcgctctt tttatagcaa ctgttaattc tctttgatgc ttagcacaag ttccagatat
   121381 tcttcttggt aatatctttc ctctttcagt tatatacttt tgtaatcttt gagtactttt
   121441 gtaatctatt ttagcgtttt tgtcagcaca aaattgacaa actctttttt tcttacgtct
   121501 ttttttattc atcatgactt ttttccctcc tttttaaaat ggtatatcgt catcatctat
   121561 agcttggaaa ccttgtgggt ctaaaccttg aggttcaaag cttggctcaa aagctggagc
   121621 actctctcta tatgaatttt ccgatttatt cttactatcc aaagcttgta ctgatctagt
   121681 acttactttt gtaaaagttc tcttttcacc tgattgtgtc tgataattgt ctactcttat
   121741 agatccttga agtgctacta atctaccttt agttatgtag ttagcacaaa attcagcaga
   121801 tttacccatt acttcaacag gtataaaatc agtttcttta gatccatctt tttttacata
   121861 gtctctatca atggctattg taaaggatgc cactggtgtt cctgtacctg ggatgtatct
   121921 taattcaggg tctctagtca accttcccac taatacaact tgattcataa aaacaccacc
   121981 tattttttat aataaaacca gttattaagc aacaactatc atgtgtctta ttacgttttc
   122041 atttatcttt aagtttctgt ctatctcttt aggaacgtct actgctgatt tgaagttaac
   122101 taatacatag aaaccttctg taaacttagc tattggataa gctaattttt tagttcccca
   122161 agtatcaact ttaactattt ctccgtcagt tgcaacaact tccttaactt tgtttagtat
   122221 agcctctctt acttcttcat cagagtttgg ctttaccaca taaactaatt cataatttct
   122281 cactataatt cacctccctt tggacttaac ggctctacac tcttagagca gagaaatgag
   122341 actaaaatct catacctaca cattttatca tttattctta tttctgtcaa tttaaatttt
   122401 ggacaaagtt tagtataagg tgaattatat acttttcaaa caaacaaggg atggcaacaa
   122461 ccatcccttg tattatatat aagttattat ttttaattaa gcttctacac ccatagcttc
   122521 ttttaataca gctgctatat tttttatacc ttctattatt ttttcttctg gcatatttga
   122581 atagttaagt ctgaaagtat tttctctacc accattaggg aagaatcctc ctccagcaac
   122641 ataagcaaca ttcttatcta aacattttgg cattaattct ttagcattta aattacttgg
   122701 aagctctacc catgtaaata atccaccttc tggatgagta aatactaatc cttctgggaa
   122761 ctcttcttcc atagtcttaa gcattacatc tctacgttta acataaactg cttttatttt
   122821 gtcaacatgt gcatctaggt catacatatc cataaatttg cttacttcca tttgagatat
   122881 agttgatgct tgtaagtctg caccttgttt tgcaaagtta aacttagata aaatttctgg
   122941 agaagcacaa gtccatccta atctgtatcc tgggcagaat attttagaga aagttcctaa
   123001 gaatattact aatccttttg tatccattga ttttaaagat ggtaaagtct ctccttcaaa
   123061 tcttaaatct ccatatggat tatcttctat tactggtatt tcaaatttat ttactatttc
   123121 catgaatttt ttacgtcttt caagtggcca agttcttcct gttggatttt ggaagtcagg
   123181 tattacataa atcattttta ttctatcagt tgtttctagt atcttttcta attcttccat
   123241 tatcattcca tcagaatctg ttggaacatc tatgaattta ggttgataag atttaaatgc
   123301 gtttatagct cctatgtaag atggactttc acataaaatt acatcaccct catcaataaa
   123361 tacttttcct gcaaaatcta gaccttgttg agaaccactt gtaactaata tatcatcttt
   123421 gtttacatta gttttgtttt tatcattcat tctagctgct attttttctc ttaatggttc
   123481 atatccttct gttgtagtat attgcatagc tgatcttcca ttttcttcaa gcactgcaac
   123541 tgatactttt ttcatttcct caactggaaa taactctgga gccggcattc caccagcaaa
   123601 agatattatt tgtggttgtt gagtaagttt taaaagctca cgtatttctg atccttgtaa
   123661 tccttgcatt ctttttgcat atttaactgc cataattaaa gcacccccat gaaaatgttt
   123721 tcttcaattc ttattatacc aaaattttgg atattaatat acggtatttg acatttttta
   123781 agtgttaaat ttttatcact tttttattag cttttttact ctcttttcta aggtctctct
   123841 atcaagcatt attagccttg aacatttagt acattttatc tttatatcca ttcccgttct
   123901 tatgatttca aactctttac acccacatgc atgttgcttt tttaattcaa caatatcacc
   123961 tatttttaaa tccattggca taaataatta gcctcctaat ctaacttctc tacttctttt
   124021 gagccatttt ctaatttact tatacaataa attcctttta tatctacatt attttcaact
   124081 aaaatagttt ttatcttttc catatcttca aaagaaaatt taattgatat tccacaactt
   124141 gctgttattt ctcttggtgt tggaagagcc attactttta gactattttc accaaataac
   124201 ttttctgatc ttatcgcatg atgtgtcgaa ttaaatgaca ctatatacat ttgattcatt
   124261 acttaatcct ttctgactat ctatttgagt taatctttat tattaatttt atattattaa
   124321 acaaacatac attatataga aatggtattt gatgcattct ttaatgtctc aactatagta
   124381 tacatatttg taactgtacc tacttgtaat ttgtctttta aattataata atctaaacaa
   124441 gtaccacaag ataaaacttc tacacccata ttctcaagta tttttagatt ttctatggtt
   124501 tcttcatttt cagcacttaa ttttactcct ccattaacta aaagtacata cttaggataa
   124561 ggtttagatt ctgttaatgt atatataaat ccttttatta acacttttcc taattcgtca
   124621 tttccaagtc ccatcttatc tgaagatata aatatacatg tattgtctaa ttcactttct
   124681 ttattatcta caacattttg tttatctagt atatttttac cttttctaat ttctatagat
   124741 ataaaattct ctttttcgtc aacaatattt gcttcacaac ttaaagattt agcaagtttt
   124801 aatatattct ccttagctgt ttcattatcg actattgtaa ctacaacacc ttcttctagg
   124861 ttatccaatt ctctttttgt atttataact ggtttaggac aagcaagccc tctcgcatct
   124921 atttttatac tcattgtctg attcatctcc ttaaaaatat tcatacaatt tatattttat
   124981 catagatatt atcttgcttg ttatagattg tttctatacc cttataggtt tatttaccct
   125041 acattatttc taaatttttg tacataaata cacctttttg ataatattct aactcttttt
   125101 cttttgatat atttgaatat aattgaccta agtctatata taaattggcc aatattctat
   125161 tgttgcctaa atctgatact atttttatgc atttaatcag atattcaatt gcaagagtta
   125221 cttcattctg atttttatac atattagcat agaatctcaa tgctttatat tcattgaatt
   125281 tatttttatt ttttattgat gaagctaagg ctatcttaca atattttcta gctaaatcat
   125341 aatcttcttt atctatatat gcttctatta tcttaaataa tcctgacatc atgtattcat
   125401 cttcatcatt tttctttatg tcatatacct tttgtgaata ttcaagtact ctatctgttt
   125461 cacctatttt tctgtaaaca tcacaaattg ttaaatacac atttgctaat ccagttttat
   125521 tatcctcact ctcaagtatt tttagtgctt ttttaaagta atctcttgat tcttcatatt
   125581 ttccaatctc aagcatatta tttgctttta acaccaaaat atcgacatct tcttttctat
   125641 catttctatt atctatttca tttatctttt ctatgtactt caatgacata tttggattat
   125701 ctagttttat gtaacaatat gccatcttac tatatagttc cttgtgtatg ttaacatcct
   125761 caaatttatt ctctgacaaa atttcctctg caaaattaaa gtggcttata gcacctttat
   125821 aaaagtcttc ctgcatatat attttcccta tgtttaaata acacttaagt atattttcac
   125881 tatcactatt ttttataaag aagtacaatg ccttttcaaa gttttctata gcatcattat
   125941 aattagattt tttcaaatta atattagcca ttaaaaaatt acatctgcca tagttctcca
   126001 ttaaatcgta tctcttacat atatctaaaa cttcttttat ttggtcctca gccttgttta
   126061 attcattttc ttttatataa atttcgctct gtagtattaa attatcagtt atcttttttg
   126121 attgcatttc cttggtctct aataagtatt ctacacttac atctagctta tcgcctagat
   126181 attccaacag ttcataacta gtatgagatt tatccctctc tatatggctt atttgtgctg
   126241 ctgttatcct atctccagct aattctttta atgtcatgtt tttttctttt cttaattttt
   126301 taatcttttc tcctaagctc aaaatttcca tac
//
LOCUS       DAFAZV010000007       126039 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFAZV010000007 DAFAZV010000000
VERSION     DAFAZV010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 126039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 126039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..126039
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.007"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            254..1285
                     /locus_tag="KOU88_000789"
     CDS             254..1285
                     /locus_tag="KOU88_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBK3210698.1"
                     /translation="MENICDMNNKVKVAVLDTGIDKEHDYLKDNLVGGIAFECMHDYI
                     FISDKFDDEDGHGTACASIIKKEYEDVELFVIKILRKDGITNIKVLEEALRYLLDTNI
                     RLINLSLSVIGVESVKGLFEVCYELFRKGKIIVCSLANDFDLSYPAMFNNVIGVRGFT
                     LDGDDSFWYNKKYDVQCVMDSNSYISCDINNSYRLPPKCNSYLSAKLTGKIAKILSEK
                     PGITISDLNDKLESLATRNHWDSCDFDECSRIVNFKLDLYDKENALLMKVADVVRDCL
                     DIEDNNEKLFKGSLFNKEIGLVYDNCFNLLKKLEHRFDIKFNYMDISKYDLVSIYTLT
                     ELVERYKNL"
     gene            1418..2716
                     /locus_tag="KOU88_000790"
     CDS             1418..2716
                     /locus_tag="KOU88_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBK3210699.1"
                     /translation="MKYEEALEYISQTNKFGIRLGLENIGKLLELLGNPQETLNIIHV
                     AGTNGKGSVCSFVSNILRECGYKVGLYTSPYLETFTERIRVNGQNIPQDDVARIIELI
                     KEKIEIMVKEGYAYPTEFEVVTAMAFYYYSEQKVDFVALEVGLGGRYDATNIITKSLV
                     SVIVSISLDHTGILGDTIEKIAYEKAGIIKENGVVLVYDQTDEAKDVIKSVCKEKKAK
                     YIEVDFDDINIKKSDINSQIYDCTVMKETYRDLEIKLIGEHQINNSILAISVIKYLKD
                     INKLANINEESIRKGLINTKWPGRIEKIKENPIFIIDGAHNEDGAKSLAKALDKNFKG
                     RKLTLLIGMLEDKDIDSVLEILLSHFNKVITTTPNNPRAINSDILREKVLKYVDDVTS
                     KHEIEDAVNYTLETSSEDDIIISAGSLYMIGTVRTLVKKL"
     gene            complement(2830..3075)
                     /locus_tag="KOU88_000791"
     CDS             complement(2830..3075)
                     /locus_tag="KOU88_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03905 family TSCPD domain-containing
                     protein"
                     /protein_id="HBK3210700.1"
                     /translation="MKVTFNPSGVCCREMIFEVDENNVIVDAEFIGGCNGNLSGLRSL
                     IIGQNALEVADKLNGIDCGGKGTSCPDQLSKAIRQSI"
     gene            3223..4089
                     /locus_tag="KOU88_000792"
     CDS             3223..4089
                     /locus_tag="KOU88_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBK3210701.1"
                     /translation="MKIYISNYLSKSISIVDYSTLELEKEIVLEDNIYPHHFCIEKEK
                     NLIYIPSSSNGILYVLDLSNDKIIDTVSIGGSLSQVVLSDNELFVANEDSNSIYVLDK
                     NTLNPIGIIGVDNMPHGFDFDRESKKLYVPCINSIVCIDTINKNIQKKINMDFRAWHI
                     ELDKQKKEMYISTLDGKLIIIDEVSMDIKKVLYEFLLPVEIRFNYSGKKVYVADLGYN
                     NVRILDYTTSRYIGNIEINGIPQGLEISKDEKLLFVSDTQENSVKVYETANNKLIKEI
                     KVGKEPTTIICL"
     gene            complement(4093..4629)
                     /locus_tag="KOU88_000793"
     CDS             complement(4093..4629)
                     /locus_tag="KOU88_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4364 family protein"
                     /protein_id="HBK3210702.1"
                     /translation="MFENSSEELAYHKLLILYILEKIKMDLTNSQITQVVLETEMMNY
                     FSLQQLLSQLMESKFLTTYKDSDREYYALTQRGVESLEYFFNRIPTSVTEKIDKYIDS
                     NKENLLADTQVKSSFVKQSDNEFIVNLRVIENQSNLIDLNLNVSSEKQAKLICNNWKN
                     NASYMYAEVIDLLIRDIH"
     gene            complement(4820..5023)
                     /locus_tag="KOU88_000794"
     CDS             complement(4820..5023)
                     /locus_tag="KOU88_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBK3210703.1"
                     /translation="MSNSNRTVVPEAKAALNQMKLEIANEIGLSNYENIDKGNLTARE
                     NGYVGGYMTKKLVEMAERQMAGK"
     gene            5314..6078
                     /locus_tag="KOU88_000795"
     CDS             5314..6078
                     /locus_tag="KOU88_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK3210704.1"
                     /translation="MKREVKRTKALIYSVLFFSLLLVLIFVFVYGIKYICSKSDNSKM
                     PIYKVDTNEKKIALSFDVAWGTDNMDDILKILDKHNVKATFFLVGSWVDDNEEIVKAI
                     DEKGHEIGNHSNTHANLKEISKEDITKEIETTSEKIYNITGKRTNLFRPPFGDVNNKA
                     MDICSDLGYKVIKWDVDSIDWKELGPNHVIEKVIKESQPGSIVLFHANINDVDNYLDT
                     IISRLKKDGYSLVKISDLLYKDNYVVDSNGVQKTKN"
     gene            6467..7780
                     /gene="prdC"
                     /locus_tag="KOU88_000796"
     CDS             6467..7780
                     /gene="prdC"
                     /locus_tag="KOU88_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase-associated electron transfer
                     protein PrdC"
                     /protein_id="HBK3210705.1"
                     /translation="MNKLYSILLKQHVGGPDKPVVSVGDVVKKGTLIAEPTGLGANIY
                     ASVSGKISEINDQAIVIEADEVQEDTFEPLKGEGILDLIKEAGVVGMGGAGFPTHVKL
                     NIDLNGGTILANAAECEPLLAHNIKEIEERPEIVYQGIKYAMEVTNAGKGMLAIKSKH
                     PKAIEAFKKVIKPGDNIEVAELVDMYPMGEERAIVRDVLGKLLEPTQLPSEANAVVIN
                     VETLTRIVEAVEQKRPVISKNITVVGQLNSGKESIVFEDVPIGTTVGELIERAGGIKG
                     EYGEIILGGPFTGKATTLDAPITKTSGGIIVTMPFVNEKRKMGLLVCACGPNEERMRD
                     IATKMGVTDIVSVQKCKQAQEIKGALKCENPGHCPGQAQKCIEFKKAGAEVILIGNCT
                     DCSNTVMGSAPKLKLGVYHITDHVMRTVNHPLIRRIKGDVRLKIK"
     regulatory      8184..8269
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            8851..10998
                     /locus_tag="KOU88_000797"
     CDS             8851..10998
                     /locus_tag="KOU88_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-Gln thioester bond-forming surface protein"
                     /protein_id="HBK3210706.1"
                     /translation="MKTKIKKSSIISLVIAFSMVFTAFTPIVSYADEVTSNDTILNGE
                     EQSNGQTPDVEKPSDGQVPDGEKPSDSQVPDGEKPSDGQVPDGEKPSDGQIPDGEKPS
                     DGQIPDGEKPSDGQIPDGEKPSDSQTPDVEKPSDGQMPDVEKPLDEQTPEEEKPLEEK
                     IVIEEMSLKQDIDKILDMTLSQINKIVYNFWEDEEDVKADEQSEINQVFTSKDSFISL
                     WYDKKAKVKNSCLLKEIDGSDRPYHDLRFDDITKTLTFDYVIKGLVGASSKDDKYVIE
                     GEDGEQTAFCYNNHLRPPSSNGKSPYLPAEDFNGQENQNEEAVKSILYAGSEFDGFGY
                     KQQFNLGGEENELMTYSATQSAIWIILGQMDEQERLKQYQGSINLCDKLIERAKTEEE
                     RAEYQKRKEVAINTKAYLEALLKAGREELKPNDTGKPSLSNGLTKINFEKNEDGTYET
                     EAVALVGYSGVVKLKLPDGVTAYDVDGNIIGTGEVEISTQQKFKLKSVGKPDAKANIS
                     AVSYDYIFPKAIQYYKAVLDLGQKDHSSSLPSSKQNLLSYTIEKKNGQEVNFNIGLPT
                     DDDVVNPPVPPIDDDVVNPPVPPTDDTNGHKPKPSPPIDDTVINPPVPPMDDTIINPP
                     VPPTEDAVLNPPVPPMEDAVLNPPVPPTDDTVLNPPVPSVSDTVEKTPELSRDDTIIK
                     SPKTGDETQLMSYVFISVIAICGLAYQCKIKRN"
     gene            11405..13165
                     /gene="prdR"
                     /locus_tag="KOU88_000798"
     CDS             11405..13165
                     /gene="prdR"
                     /locus_tag="KOU88_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54 dependent transcriptional regulator
                     PrdR"
                     /protein_id="HBK3210707.1"
                     /translation="MFSIPEVKKVEEVMDTKFTTIDEDTRIEDAIKEMIKSNTKTLMV
                     IDSSDQLKGIISMTDIHNLYEMHKKYEGQPVKLIMKKDVIYVNEGLTLDECRDIMILK
                     NIGILPVLRDNKIIGVLKQEHIRDYLYMHLEDYGLTLKYIIGQIKEGICAINNEGVVI
                     LWNKFMEERYDIKSEDIVGRPMNEFLENTISEKVLNSKVGMSDLYFTDKKENMYALVH
                     ANPIFYKEEFIGVVCTEVDVTEAKILALELEKVNDTLKYLKNEVKNLSKGSFDKILGK
                     SYKLEKSKAIAKQVARTNSSIFIWGESGTGKEVFARAIHDYSERKGQFIPVNCSAIPN
                     ELFESEFFGYESGAFTGASKKGRIGIFELAKDGTVFLDEIADLPLSMQAKLLRVLQEK
                     EIRRVGGDTTIKINPRIISATNKDLSKMVKAEKFREDLYYRLNVVEIKIPPLRERKED
                     IGLLVHSFLEEICKQNNKPVLTISKDVIDIFQNYRWKGNIRELKNTIENIVVLSQNSK
                     IDVDDVPSYMMDSTNNSTEEEEYPLDLTKATQKIEIKNITKALKMSNGNKAKAAKILN
                     IPRTTLYYKIDQYKIDVSKI"
     gene            13594..15474
                     /gene="prdA"
                     /locus_tag="KOU88_000799"
     CDS             13594..15474
                     /gene="prdA"
                     /locus_tag="KOU88_000799"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-proline reductase (dithiol) proprotein PrdA"
                     /protein_id="HBK3210708.1"
                     /translation="MSITLETAQAHANDPAVCCCRFEAGTIIAPENLEDPAIFADLED
                     SGLLTIPENGLTIGQVLGAKLKETLDALSPMTTDNVEGYKAGEAKEEVVEETVEEAAP
                     VSEAAVVPVSTGVAGETVKIHIGEGKNISLEIPLSVAGQAGVAAPVANVAAPVASAAA
                     EVAPKVEEKKLLRSLTKKHFKIDKVEFADETKIEGTTLYIRNAEEICKEANETQELVV
                     DMKLEIITPDKYETYSEAVLDIQPIATKEEGELGSGITRVIDGAVMVLTGTDEDGVQI
                     GEFGSSEGELNTTIMWGRPGAADKGEIFIKGQVTIKAGTNMERPGPLAAHRAFDYVTQ
                     EIREALKKVDNSLVVDEEVIEQYRREGKKKVVVIKEIMGQGAMHDNLILPVEPVGTLG
                     AQPNVDLGNMPVVLSPLEVLDGGIHALTCIGPASKEMSRHYWREPLVIRAMEDEEIDL
                     VGVVFVGSPQVNAEKFYVSKRLGMLVEAMEVDGAVVTTEGFGNNHIDFASHIEQIGMR
                     GIPVVGVSFSAVQGALVVGNKYMTHMVDNNKSKQGIENEILSNNTLAPEDAVRIMAML
                     KNAIEGVEVKAPERKWNPNVKLNNIEAIEKVTGEKIVLEENEQSLPMSKKRREIYEKD
                     EN"
     gene            15555..15839
                     /locus_tag="KOU88_000800"
     CDS             15555..15839
                     /locus_tag="KOU88_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210709.1"
                     /translation="MDRLKYISSETFYEGIIVDIKGGGVTIDLKGRLGQFKIPNRMLI
                     TDYELKIGQEVGFMLSYPEVLSPEPNQEYVENIRREKEKQAEMQSKQEEK"
     gene            15877..16602
                     /gene="prdB"
                     /locus_tag="KOU88_000801"
     CDS             15877..16602
                     /gene="prdB"
                     /locus_tag="KOU88_000801"
                     /EC_number="1.21.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:16327..16329,aa:Sec)
                     /transl_table=11
                     /product="D-proline reductase (dithiol) protein PrdB"
                     /protein_id="HBK3210710.1"
                     /translation="MSLTTVQGLQSEIFVPITPPPVWTPVTKELKDMTIALATAAGVH
                     LKSDKRFNLAGDTTFRAIPNTATVDEMMVSHGGYDNGDVNKDINCMFPIDRLHELAAE
                     GFIKGVAPMHYAFMGGGGNQHVFTEETGPAIAAKLKEEGVDGVVMTAGUGTCHRTAVI
                     VQRAIEEAGIPTIIIAALPPVVRQNGTPRAVAPLVPMGANAGEPHNIEMQTHILRDTL
                     EQLVAIPSAGKIVPLPYEYKAHV"
     gene            16682..17440
                     /gene="prdD"
                     /locus_tag="KOU88_000802"
     CDS             16682..17440
                     /gene="prdD"
                     /locus_tag="KOU88_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase cluster protein PrdD"
                     /protein_id="HBK3210711.1"
                     /translation="MEEKIMRRLVIKPFHMNEVNFGSKTSIKKDVLTIDLSSIDEIKE
                     REELITDIKVDIIKPGDYDREINTIMDIIPISTKVLGRLGEGITHTLTGVYVMLTGAD
                     EDGNQMHEFGSSEGILKDQMVFGRYGTPSVEDYIIHVDVTLKGGLPFERTLPLAAFRA
                     CDDFIQEIRASLKMEDGRNATQVREYFDKIRPNAKKVVIVKQIAGQGAMYDNQLFSKE
                     PSGFEGGTSIIDMGNVPMIISPNEYRDGALRAMT"
     gene            17455..17922
                     /locus_tag="KOU88_000803"
     CDS             17455..17922
                     /locus_tag="KOU88_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBK3210712.1"
                     /translation="MGIGPSTKETSLHHFRDPLLDIVESDKDVDLLGVIVVGTPDGNE
                     NKTFVGQRTAAWLEAMRVDGAIVSSDGWGNSHVDYANTFEEIGKRDIPVVGVTFNGTQ
                     AKFVVSNQYMDTIVDMNKSKEGIETEVVGENNTNEIDAKKALAFLKLKMRKHG"
     gene            17940..18422
                     /locus_tag="KOU88_000804"
     CDS             17940..18422
                     /locus_tag="KOU88_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline reductase"
                     /protein_id="HBK3210713.1"
                     /translation="MSFVGISTSMKNTSLHIFRDPLLDLIDNDSDIDLLGVVVVGTSE
                     HNEWKTFLATRLGRWIESLRPDGVIITLDMAGNQHIDFTNAIAEFVKSDIPTVGLTIM
                     GADGLVITNPYLDKATIIDYKKTTGYIETEVVGDNHMDEVDVKKALAFLKLKMRKDAK
                     "
     gene            18442..19449
                     /locus_tag="KOU88_000805"
     CDS             18442..19449
                     /locus_tag="KOU88_000805"
                     /EC_number="5.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline racemase"
                     /protein_id="HBK3210714.1"
                     /translation="MKFSRSIQAIDSHTAGEATRIVVGGIPNIKGNSMPEKKEYLEEN
                     LDYLRTAIMLEPRGHNDMFGSVMTQPCCPDADFGIIFMDGGGYLNMCGHGTIGAMTAA
                     IETGVVPAVEPVTHVVMEAPAGIIRGDVTVVDGKAKEVSFLNVPAFLYKEGVEVDLPG
                     VGTVKFDISFGGSFFAIIHASQLGLKIEPQNAGKLTELAMKLRDIINEKIEIQHPTLA
                     HIKTVDLVEIYDEPTHPEATYKNVVIFGQGQVDRSPCGTGTSAKLATLHAKGELKVGE
                     KFVYESILGTLFKGEIVEETKVADFNAVVPKITGSAYITGFNHFVIDEEDPLKHGFIL
                     K"
     gene            19569..20450
                     /locus_tag="KOU88_000806"
     CDS             19569..20450
                     /locus_tag="KOU88_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBK3210715.1"
                     /translation="MVAILKALYVVFAAIFAVVFGKDVAKANKEGKLEEQSTPKVAVT
                     GFITDFFDTLGIGSFAPTIAMSKALKLNIPDKKMPGTLNVAHTIPVVTEAFIFTSIIP
                     VDGVTLVSMVVAAAVGSYIGAGIIAKMDERKIQLVMGVTLALTAILMLLGHPWINVLP
                     GGGNELGLTGVKLVIGVIGNFILGALMTAGIGLYAPGMAMVYFLGMSAKVAFPIVMGS
                     CALLMPVASMKFIKEDAYTKKASVIIAICGLIGVFVAAYIVKTLPMDILKALVIVVIA
                     YTSATMIMAANKNKKTA"
     gene            21118..21753
                     /locus_tag="KOU88_000807"
     CDS             21118..21753
                     /locus_tag="KOU88_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK3210716.1"
                     /translation="MIAVKDENNVVNLRGELDNKLEFSHEIFGEKFYNMKIKINRLSD
                     SFDILPMTVSERLLQDIDLDKQNLVNVVGQLRSYNKTLNNKNRLVLTVFVREIKSIDE
                     ENKDPNSIFLDGYVCKEPVYRKTPLGREITDLLVAINRPYNKSDYIPSIVWGRNAKFA
                     KNLKVGDRIQLWGRVQSREYEKKIDENNVVKKMAYEVSISKIKKLDENNNE"
     gene            21937..22506
                     /locus_tag="KOU88_000808"
     CDS             21937..22506
                     /locus_tag="KOU88_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK3210717.1"
                     /translation="MKSILCQINKQPVKAKYTSDELECFLDTIEYNVGDKILLVGHIG
                     NLGKRLRGLGTSVTILENSNYEDVCYSLVYNENCNVVKGKLEFLPFDDNQFNKIIIVD
                     QFNVITDCEKASSEIQRVLKGNGEVILEDLNLKNLKVKLNYLKHKFCGSVAKIHYPHE
                     VFNIFSRLNFDGMIKESNKLKYIYVGKRR"
     gene            22584..22721
                     /locus_tag="KOU88_000809"
     CDS             22584..22721
                     /locus_tag="KOU88_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210718.1"
                     /translation="MEINYELIIIVMLFVILMSIQFTLNKIYLILKEIRQILMLKKNK
                     E"
     gene            22718..24493
                     /locus_tag="KOU88_000810"
     CDS             22718..24493
                     /locus_tag="KOU88_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3210719.1"
                     /translation="MMIMIGLEYIKSDIQNIAEAIVSVLNIDVTIVNKELFRIAGTGV
                     YIDKIGEKVDKYTAFKKSLTEQITILIDDPKSSDICRECYKSGACVEFAEVCCPIICD
                     GDSHGVIGLIAFTKEQAQIIENNKSGLINFLGKMADLISNKLKAQIKTYELELEKKKL
                     ETLLNNMDKAVVSIDVDGKVDKYNSKFKELFNIKDSITGKNIFVELDFIKKPSINNFK
                     KDKSCSFFYKRYGYDSKGIYNINKIVLKNELKGYVIDFIDKRDAIKNYNKMNKDYRIK
                     LENIIGESVAIRNSKKEALIASKSTSTVLITGESGTGKELFARAIHNHSNRVDNPFIA
                     VNCAAIPDNLLESELFGYEEGAFTGAKKGGKLGMFEVAHKGSIFLDEIGDMSLHLQSK
                     LLRVLQEKELNKIGSKSNVSIDVRIIAATNKDLEKMVQNGTFREDLYYRLNVIPIKLP
                     SLRERKEDIPLIIKHMVKEYSKKLDKNVIDIDSRVVDAMMEYKWPGNIRELQNIIEYS
                     VNMSSSSIITMNVIPQKIKNTSVEELEVKSDRIIPLDELEKIEIIKALNKYKDYKKDK
                     ELTAKALGISRATLYRKIEKYNIIS"
     gene            24917..26224
                     /locus_tag="KOU88_000811"
     CDS             24917..26224
                     /locus_tag="KOU88_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBK3210720.1"
                     /translation="MRDIRKELVEMLKAEVKPAVGCTEPVALALACAKAKELLGEEIV
                     ENRMLVSPSIYKNGMCVGIPGTERLGLKIAAALGIVGGHSENGLSVLETLTKEEVKIA
                     EDYMDNTPLSITPADTREKVFIEVVLKGKNHIAKVRIRTKHDNFTFLEKDGEVLLDNE
                     PKVSASNDVAEKAESLMDTVTIQELIKNVEGIDFKDIEFLLDGVKMNEEMAEYGLKQK
                     TGIGVGYGIKKSIEEGLLGNDVINYAMMLTAGASDARMAGVKMPVMSSNGSGNHGLTA
                     ILPIVAYNKKFPQSDERLAKALAISHLVTGYIKNYTGRLSAVCGCGVAASTGATAGIS
                     WLMNGTEKQIEGAIENMIADLSGMICDGAKAGCALKLSSAASAAIQSAIIAKQDCFVP
                     PLNGIVGSSVEQSIQNLGRVSDKGMSITDEIILNVMNDMNKVD"
     gene            26552..27091
                     /gene="hpt"
                     /locus_tag="KOU88_000812"
     CDS             26552..27091
                     /gene="hpt"
                     /locus_tag="KOU88_000812"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBK3210721.1"
                     /translation="MDIETKKWEVLYSEEKIKDKLRELGAIIEKDYKDKNLMVVSLLK
                     GSFIFCADLVRNINLPLRVNFMTTSSYGNNEESTGKVKVVSDVTTDIAGYDVLVVDDI
                     TDSALTMDFVLKHLKAKNPASLKCCVLLDKPSRRKVDLVPDYCGFEIEDKFVVGYGFD
                     FGDYYRNVPYIFNVTDEDR"
     gene            27449..29125
                     /gene="bclA2"
                     /locus_tag="KOU88_000813"
     CDS             27449..29125
                     /gene="bclA2"
                     /locus_tag="KOU88_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA2"
                     /protein_id="HBK3210722.1"
                     /translation="MSDISGPSLYQDVGPTGPTGATGPTGPTGPRGATGATGANGITG
                     PTGNTGATGANGITGPTGNMGATGPNGTTGSTGPTGNTGATGANGITGPTGNTGATGA
                     NGITGPTGNKGATGANGITGSTGPTGNTGATGANGITGPTGNTGATGATGPTGLTGAT
                     GATGANGITGPTGNTGATGANGVTGATGPTGNTGATGPTGSIGATGATGTTGATGPIG
                     ATGPTGADGEVGPTGAVGATGPDGLVGPTGPTGPTGATGANGLVGPTGPTGATGANGL
                     VGPTGATGATGVAGAIGPTGAVGATGPTGADGAVGPTGATGATGVNGATGPTGAVGAT
                     GANGVAGPIGPTGPTGANGVAGATGATGATGANGATGPTGAVGATGANGVAGAIGPTG
                     PTGANGATGATGATGATGANGATGPTGATGATGVLAANNAQFTVSSSSLVNNTLVTFN
                     SSFINGTNITFPTSSTINLAVGGIYNVSFGIRATLSLAGFMSITTNFNGVAQNNFIAK
                     AVNTLTSSDVSVSLSFLVDARAAAVTLSFTFGSGTTGTSAAGYVSVYRIQ"
     gene            complement(29632..30387)
                     /locus_tag="KOU88_000814"
     CDS             complement(29632..30387)
                     /locus_tag="KOU88_000814"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBK3210723.1"
                     /translation="MLKVIISGYNGTMGRVLAECVKKDNELELVCGVARSADEKGHHS
                     DTKLYKTMTDVTEKTDVIIDFSHHETLEPILSYALKNNTPVVLATTGYDENDLNKIEE
                     ASKNIPILLSSNTSLGVNILIKLVKDASKMLEGFDIEIIEKHHNRKEDAPSGTATMIA
                     NAIREVLPESENTHGRYGRDCKRKPNEIGIHSIRGGNIISDHDVIFAGDNEVLTLSHH
                     SQSDEVFANGSIVAAKFLIGKQSGLYKMSDILG"
     gene            30827..31816
                     /locus_tag="KOU88_000815"
     CDS             30827..31816
                     /locus_tag="KOU88_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBK3210724.1"
                     /translation="MLKEEKTYQEKDAKVFNGVAALIMILLFLVVSIGIMVFGIVKLD
                     SGFTGIGSLMLILGLVFIVVDFILFFGLRMINPKEAIVLVLFGNYYGTIKKEGYYWVN
                     PFCSAINPAVSRINVSKSSSDEKVDISTNSRGKKVSLKTMTLNNEKQKVNDLLGNPII
                     IGVVVIWKVIDATKAVFNVDNYNTFLSIQCDSTIRNVSRLYPYDVSEDGDEKSLRGSS
                     QEIADRLKDELQSRVDIAGIEVCEVRITHLSYAPEIAAAMLQRQQAEAIIAARKKIVE
                     GAVSMVEMALTNLSENNVVTLDEERKAAMVSNLLVVLCGNKDAQPVVNSSSIY"
     gene            complement(32268..32984)
                     /gene="dapD"
                     /locus_tag="KOU88_000816"
     CDS             complement(32268..32984)
                     /gene="dapD"
                     /locus_tag="KOU88_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBK3210725.1"
                     /translation="MVNLNDAYEIARYIKEVKKKTPVKVYVNTNSLHFQSTDKFKVFG
                     NNGSYIFVGDYDDIMEVLDKHGNDITDTHVEYDRRNSAIPLKNTLSEHARIEPGAIIR
                     DMVTIEKNAVVMMGAVINIGAVIGEGSMVDMNAVIGARGTLGKNVHLGAGAVVAGVLE
                     PPSATPVIVEDDVLIGANAVILEGVRIGKGAVVAAGAVVTTDVEAGAVVAGSPAKVIK
                     MKDEKTADKTKLMEDLRNLD"
     gene            complement(33208..33957)
                     /locus_tag="KOU88_000817"
     CDS             complement(33208..33957)
                     /locus_tag="KOU88_000817"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBK3210726.1"
                     /translation="MLKVIATGYDGKMGKILADTIREDNELELVCVAARGLDSYEGDL
                     KIYEDMSTIVEEADVVIDFSHHSNLDNILSYVLKTKTPLVIATTGYNDDEMNKIREAA
                     KVIPVFQSYNMSLGVNVLVKLVKDAAKLLEGFDIEIIEKHHNRKVDAPSGTAVMIANA
                     IKEVLPNVENNYGRYGRSAKRQPNEVGIHAIRGGNIVGEHDALFAGDNEVLTISHQAQ
                     SRGIFASGSIAAAKYLVKQKPGFYNMDSMLG"
     gene            complement(34024..34911)
                     /locus_tag="KOU88_000818"
     CDS             complement(34024..34911)
                     /locus_tag="KOU88_000818"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBK3210727.1"
                     /translation="MIFKGSAVALVTPFTKDNKVDFDKLGELVEYQIANGTDAIVSCG
                     TTGEANTMTDEEQLATIKYVVEKVNKRVPVIAGSGSNDTMHSVNLSQEAEKLGVDALL
                     IITPYYNKANKAGLKRHFETIANSVKLPIILYNVPGRTCVNISPSLIVELAKIDNIVA
                     VKEASGDLGQVAEIASLVPDDFAIYSGNDDTILPLLSLGGQGVISVLANVCPQETHDL
                     VAKFFEGDIEGSRKLQLGMDALIAALFIEVNPIPVKTAMNLLGFNVGDLRLPLAEMDP
                     ANLEVLKKELVNFGLKVNA"
     gene            complement(35028..36029)
                     /locus_tag="KOU88_000819"
     CDS             complement(35028..36029)
                     /locus_tag="KOU88_000819"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBK3210728.1"
                     /translation="MKKVNVAIVGATGMVGRTFLKVLEERNFPIENLFLFSSSKSAGS
                     KVMFCGKEYIVEELKETSFTDRGIQIALFSAGGSISEKYAPIAASNGILVVDNSSQWR
                     MNPDVPLVVPEVNPEAIKNHKGIIANPNCSTIQAMVPLKALDDKYKIKRVVYSTYQAV
                     SGSGVKGVEDLEKGMNGNPTGFYPHQISYNCLPHIDSFTENGYTKEEMKMVNETMKIL
                     DNYDLKITATTVRVPVKNGHSESINVEFNNPFELDDLVKTLEEAPGVVVVDNPAKNEY
                     PTAVEFDDRDEVFVGRIRRDFSVDNGVNLWVVADNIRKGAATNAIQIAEMALSYDLV"
     gene            complement(36454..37335)
                     /locus_tag="KOU88_000820"
     CDS             complement(36454..37335)
                     /locus_tag="KOU88_000820"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBK3210729.1"
                     /translation="MLFKGSAVALVTPFTEDNNVNFEKLGELIEYHIENGTDALVVCG
                     TTGEATTMSESEIFAVIKYTVEKVNKRIPVIAGTGSNNTMLSVHMSQEAEKLGVDGLL
                     IITPYYNKTNEKGLKLHFETIANSVKLPIILYNVPGRTKVNIKPSVVAELAKIDNIVA
                     VKEASGDLAQVAEIAKLVPKDFAIYSGNDDTILPLLSLGGSGVISVLANICPKETHDL
                     VTKFFEGDIEGSKKLQLDMDALIAALFIEVNPVPVKTAMNILGFNVGDLRLPLAEMEE
                     TNLNVLKQELTNFGFKF"
     gene            37658..38851
                     /locus_tag="KOU88_000821"
     CDS             37658..38851
                     /locus_tag="KOU88_000821"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBK3210730.1"
                     /translation="MDTLKELFKIGSGPSSSHTMGPQRAAERFKNENPDAESFRAILY
                     GSLAATGKGHLTDYIIEKTIAPKKVEIVWEEDIIKDFHPNGMKFEALDKDKNVTAEWT
                     VYSVGGGTIAEEGQRNSKSNSIYHLDTMDEIVKWCKENNKTLVDFVLECEPKDIKDYI
                     KTIKDAMRKSIDDGLSTDEIIPGKLLLKRRASTFYNAYKKDKSFSTLVYAYALAASEQ
                     NASGNIIVTAPTCGSAGVIPGIFFAMQDFYNYDDEKIIEALLVAGIIGNIIKTNASIS
                     GAEVGCQGEVGAACSMAAAAVAYLKGGTIDHIEYAAEIALEHHLGMTCDPVYGYVQIP
                     CIERNAMAAQRAYDAANYALLTDGSHSVSLDQVVETMKETGIDMMDKYKETAKGGLAK
                     HFFSC"
     gene            39057..40175
                     /locus_tag="KOU88_000822"
     CDS             39057..40175
                     /locus_tag="KOU88_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HBK3210731.1"
                     /translation="MREASYLQEQLYKHRKSLNPIAEIGRKEYKTSKYIRDYLDKLGI
                     EYEVYLETGIVGVIEGKRPKKDIAFRADIDGLHSEEGVKHLCGHDGHATILLGLIEYL
                     NDNKEDLNDNIVFIFQPAEEGPGGAKALIDEGVLRKYNIDEIYGLHIYPELPEGYVGT
                     REGYFMAQIGDIDIEIVSKSGHGAMPQNGIDGIVIASNFVSSLQTIVSRNISPIDNAV
                     LTIGRIEGGARRNIIAENIKMEGTMRCFSPEVYEKMKLRVRELARGFELAYNCKVNIN
                     IIDDYIAVKNDKDLYQEFVEAIGSDTVVELEPLMISEDFSYYQKEVPGLFFMLGSRNE
                     EKGFVNGLHNINFNFDEKICVNALNVYLKLLKYKEAID"
     gene            40306..40551
                     /locus_tag="KOU88_000823"
     CDS             40306..40551
                     /locus_tag="KOU88_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small, acid-soluble spore protein, alpha/beta
                     type"
                     /protein_id="HBK3210732.1"
                     /translation="MKEKVQREKKITNGKNTKILTNDDIMKYEIASELGLMDKVGERG
                     WAGLTAKEAGRIGGMLTSRKKRLKKIVEEQNKKDESI"
     gene            40538..41284
                     /locus_tag="KOU88_000824"
     CDS             40538..41284
                     /locus_tag="KOU88_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK3210733.1"
                     /translation="MSQYSDFAFVYDELMNEVDYNGWVKYIEDIIDSEGVKVKNILEL
                     ACGTGNLTIPLAKKNYDIAGIDISDEMLSVAREKAEKEGVELVLLQQDISELDFEISD
                     LDCVLCACDGFNYITYDDDLENVFSKTYELLKKDGIFIFDISSFYKLANILGNNMYGE
                     NREDIAYMWQNYFDEEENLIEMELTFFIKDECGKFERFEEIHQQRAYTEDEIVDMLEK
                     SGFKDIKYYGDFTFDKPSEESQRIFFVCKK"
     gene            41567..42442
                     /gene="hslO"
                     /locus_tag="KOU88_000825"
     CDS             41567..42442
                     /gene="hslO"
                     /locus_tag="KOU88_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBK3210734.1"
                     /translation="MRDYVLRATSGNGQVRAFVATTRNTVEEARRLHETTKVATAALG
                     RTLTATSIMGLMMKNDSDKLTVIIKGGGPIGTIIATSDSKGMVKGYVGNPQVEVEDYP
                     NGKLNVAAAVGTEGVVKVIKDLGLREPYNGTYPLVSGEIAEDFTYYFAVSEQTPSVVA
                     LGVLTKEDEVEFAGGFIVQLMPDAEEETIAKLEENVAKLPSITNMLKEGKSPEDILNI
                     VLDGLEPKILDTCEVGFMCECSKERVKTALVAIGKKSLAQIIEEDKKAEVGCQFCNKK
                     YMYSEEELLEILKEM"
     gene            42833..43633
                     /locus_tag="KOU88_000826"
     CDS             42833..43633
                     /locus_tag="KOU88_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBK3210735.1"
                     /translation="MESKTKYIGISILILLMIFLIAKNFNGKLEIPIPESNSRKFKSA
                     AVFYPQHQDDEVLWGGSAIVDAIKQCGVDNVYVVLVSDGSGVNVFKANTKFRNLTRKQ
                     KEELRNNEFKSALRELGVKPQNVIILADIDKKEGIHYELMEKTILDFEHKFKGNVTHI
                     AHHYKYDDHIMHRKNGEVLKKLKREGKIKDDLYFVKPKYVKYIPRNERAIYKAMDFDD
                     YNKVKSACYEYKVVNSKRKMYGIGYISAHSYFEHLLNDPELTSVLSED"
     gene            44160..46400
                     /locus_tag="KOU88_000827"
     CDS             44160..46400
                     /locus_tag="KOU88_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBK3210736.1"
                     /translation="MNNEFIILKGCKENNLNNISLKIPKRKITIFTGVSGSGKSSIVF
                     ETIAKESQRQLNERFSTFVRSFLPKYGEVKADCIENLSTPIIIDQSRLGGNSRSTLGT
                     ITDVNSFLRALYSRFGSEYIGNANMFSFNNIDGMCPHCHGLGKKLVPNMNQILDMNKS
                     LNEGAILLSGFGVGSWHWNIFAESGFFDINKRICDYSEVELEKFLHGKAEKIKIENAG
                     QTNMTYEGLMVKFNRLYLSREGEISEATKKKLSKLLIEDRCPICDGRRLNERVYRSLI
                     NGYNIADLTSMQIDELAEVIKSIDEAEAQPLIKGIIEKLNSIIDIGLGYLTLDRETSS
                     LSGGESQRIKMVKYLNSNLVDLMYIFDEPSVGLHPKDVYKLNNLLKKLRDKGNTIIVV
                     EHDPDVIKIADHIVDVGPKAGKYGGEVVYEGSYENLLTSGTLTGNALSKFLPIKESVR
                     EHSGYLEVKNCNKNNLKNVSIKIPKGVLTLVTGVAGAGKSTLIKDEFLKQNPSAVLID
                     QSPVSANSRSSLATYSGIMNNIRSIFSKTNGVNASLFSSNSEGACDNCKGSGIVEMNL
                     AFMESIKSTCNVCEGKKFKKEVLEYRFQGKNIIEVLEMSVLDAIEFFNLKQIKTKLQC
                     IEKMGIGYLTLGQTLDTLSGGECQRLKLASELNKESSVYILDEPTTGLHMADIENFIS
                     IIEEIVDNGNTVIIIEHNIDVIKRADWIIELGPEGGTKGGRVIFEGIPKQLCNNKISL
                     TAKYIV"
     gene            46814..48349
                     /locus_tag="KOU88_000828"
     CDS             46814..48349
                     /locus_tag="KOU88_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK3210737.1"
                     /translation="MINDILTLLSERSDFFIKLSIEHLMISIISIIIAIVLGGIIGII
                     VSEFHNSSKPILGTINFLYTIPSISMLGFLIPFSGIGNTTAVIALTIYALLPMVRNTY
                     TGITNVDKNILEAARGMGSTDFQILYKIKLPLALPVIMSGIRNMVIMTIALAGIASFI
                     GAGGLGVAIYRGITTNNTIMTITGSILIALLALIFDFILGLVEKFFQRKRKKKNRKKV
                     FAILGSLILIVIIFTSYLFNPSKTQTIHIATKPMTEQYILGEMLDILIEKNTGLNVEI
                     TQGVGGGTSNIQPAMENGEFDIYPEYTGTGWNMVLKKNELYTESMFSKLQSEYKTKLK
                     MQWTGMYGFSNSYALAVRKEVADKYNLKNITDLKDVSSKLTFGAEYDFYEREDGYTPL
                     CNTYGLNFKDTVDLDIGLKYQAINEGKIDVMPIFTTDGQYSVSDVVVLKDDKNFYPSY
                     QCGNVVRLEVLEENPELSKVFKMVGDILTDKEMAKMNYDVENNNLEPREVAREFLNKK
                     GLL"
     gene            48365..49126
                     /locus_tag="KOU88_000829"
     CDS             48365..49126
                     /locus_tag="KOU88_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210738.1"
                     /translation="MTPIIQFKNIKKQYNDKTIIDNLNLDIEKGEFLTVIGSSGSGKT
                     TLLKMINGLILPDGGNILINQTDIKNEDLIKLRRRIGYCVQGSVLFPHMTVEENISYV
                     PNLLSKKNKLEVKSAVNKWMEIVGLPNDMKVRYPSELSGGQQQRVGIARALASSPEIL
                     LMDEPFGAVDEITRKQLQKEIKEIHKKTGVTIIFITHDIYEALILGTKTLVLNHGVVQ
                     QYDTPENILNTPANQFVDQLLNIRKSIIDDDNLKE"
     gene            49464..50333
                     /locus_tag="KOU88_000830"
     CDS             49464..50333
                     /locus_tag="KOU88_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK3210739.1"
                     /translation="MDNNLITIEKTLDYIEKHLLDEMLDLNVISKEIGYSKYHLHRMF
                     TSVVGFSVHNYIQRRRLTEAARMLIFTEKPIIEIALISGYDTQRSFSRGFKKMFKRSP
                     NFFRRHQDFLPLQLKFDIHNRKKLRGDMVLDVKKVNCADINIVGYSGKVRKGFHIIGK
                     CWRDLHKNKEMIENKVDLGFLIGVSDYSNFKEIENTPTFTYIAGAQVATFGKLPNGME
                     KFVLPKSNYIVFTFIGKNEDSMQNVVEYIYQEWFPNSSCQFNENNLYDFVKYGEKTDE
                     NGLSEIQFWVPII"
     gene            50662..50913
                     /locus_tag="KOU88_000831"
     CDS             50662..50913
                     /locus_tag="KOU88_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBK3210740.1"
                     /translation="MNVENELLKNLDRLHTTELGVVRIKKNLSLETNDVVNWCKTKIE
                     SPNAIINRKGKNWYISVYDCIITVNAHSYTIITAHKEKK"
     gene            51025..51804
                     /locus_tag="KOU88_000832"
     CDS             51025..51804
                     /locus_tag="KOU88_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK3210741.1"
                     /translation="MNDTVKEKLAESLTSDTTDILPYLPYLLQDFWELGSSPEQMLQL
                     FRKHIPFNEDTKVLDLACGKGAVSVKLAKELNIHIKGIDLIPEFIDYARRKAIEYKVD
                     ALCDFEMNDANSSVKIEHDYDCVIFGAVGDILGNYKETISKLLPTIKSKGFILIDDAY
                     VVDKSTNEQLNFERVYPTYNEWCILFKELGLKLIECIPCLELENDVEEEMNWIITRAN
                     ELIKKYPSQKDMFEQYVISQKNEYTDLQQDLVGATWILQKE"
     gene            complement(51939..52589)
                     /locus_tag="KOU88_000833"
     CDS             complement(51939..52589)
                     /locus_tag="KOU88_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210742.1"
                     /translation="MNIVMINGSPKVNKNNSQYFLSELKQLIQNDNKVFTFKVDSTSK
                     YPDALNAILNCDRLIIASPLYVDGIPSHLLHFLEKCEKFLKTQNKKPIPVYAIVNCGF
                     NEGEHNHLAIQMIEHWCKKINFTWVQGIGIGAGEMFGSLESVPLGKGPKKDLGIALKE
                     LSKNILSDNIHIDDSNKSTIFISPNFPRFLYKLMGNHQWNTQAKSNGLTKSDILKK"
     gene            complement(52586..53089)
                     /locus_tag="KOU88_000834"
     CDS             complement(52586..53089)
                     /locus_tag="KOU88_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3210743.1"
                     /translation="MRLLIHDLTDKELEKLLPKLDDNIKILPNTKEIHKCIGCFGCWI
                     KTPSECVVKDYYSNMGKLINDSDGIIIISRCCYGGFSPFVKNVLDKSINYILPYFVIK
                     DNMMRHKSRYDKQINLKAIFYGDCITEAEKETATKLVNGNAINFNIKEHSVCFYENIQ
                     DIRGESI"
     gene            complement(53138..53653)
                     /locus_tag="KOU88_000835"
     CDS             complement(53138..53653)
                     /locus_tag="KOU88_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK3210744.1"
                     /translation="MLEYIILGFLMEKELSGYDLKQIMSESTSYFFDASFGSIYPALK
                     RLETKGYIHYHEVIDGSKLKKLYSITNTGKEVFLEWLKKPINFSKTKQDHLVNIFFYK
                     YLPKEIIETNLKMLITEVELLLNKLSKQKNDAEENHCVDQYTYMYATMIYGVDYYNFV
                     INWCKDLLKNL"
     gene            53933..54460
                     /locus_tag="KOU88_000836"
     CDS             53933..54460
                     /locus_tag="KOU88_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3210745.1"
                     /translation="MHEQIDCCERKKIKTINIKGENMRELLKWVSIINRYNTNYIDRK
                     LADIGINNSQYFYVLHICNNPGITQDTIFEKILVNPSNITRALANLEKEGFITREPGV
                     KDKRTWHLYPTEKSLECYDEILKITNGYVEELLSSFEKEEQELFMSMLKKVAFLAIDM
                     NEEAKLEAKENGRKI"
     gene            54444..55847
                     /locus_tag="KOU88_000837"
     CDS             54444..55847
                     /locus_tag="KOU88_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3210746.1"
                     /translation="MEEKYKEPLEYEKVSKLLTKYAIPSIIAMLVSALYNIVDQIFIG
                     QGVGVLGNAATNVTFPLTTICTAIALLLGIGGASKCSLELGAKNSEKATKAAGNSICL
                     MAVFGISLFIVVSIFLTPLLKFFGSTSEILPYAHTYTKITSIGLPFLIMSTGMSKLIL
                     ADGRPKASMFCMLIGAVINTILNPLFIFVFNMGIAGSALATVIGQLISFGISVHYIKN
                     FQHIKLHKKSFKLDSIIYKHIFALGSSSCFNQLAMTVTQIVMNNTLAYYGARSVYGSE
                     IPLACVGIIIKVNMIFISIIIGISQGMQPIIGYNYGAEKYNRVKEAYKFAVGSATIIS
                     VIAFLCFQFFPRQITSIFGNGNETYFIFAEHYFRTFLFLTFINGVQIVSSTFFTSIGK
                     SVLGLFTSLTRQILFLIPLIVILPMFMGIDGVMFAGPIADAAAAMVCIYFAVHEMKSL
                     TIKQNNLMSNHNKIAEV"
     gene            complement(56366..56677)
                     /locus_tag="KOU88_000838"
     CDS             complement(56366..56677)
                     /locus_tag="KOU88_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210747.1"
                     /translation="MKKIIKSFTFWFFLIALFEIYMHQIGQDSKSIVLIGLNPILSII
                     SRVDSFFVFMDSGMQIPCRTITGSISIYWYIASILSFLIYGIILDLIRIVISKIGNKT
                     K"
     gene            complement(56733..57326)
                     /locus_tag="KOU88_000839"
     CDS             complement(56733..57326)
                     /locus_tag="KOU88_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK3210748.1"
                     /translation="MISDSISKRRSIRKYKNQSISHETIEKIIEAGINAPSSKNRQPW
                     RFVVITEKEKESMLKAMSKGIQNEINDNGLLPGSRQHIAGANYTVEIMKQAPVTIFIL
                     NILGKSPLEKLSPEERFYEMANMQSIGAAIQNMSLTAVELGLGSLWICDVYFAYRELC
                     EWLNTDSQLVAAISLGYPDEEPSRRPRLQLSDVTEWR"
     gene            57890..58120
                     /locus_tag="KOU88_000840"
     CDS             57890..58120
                     /locus_tag="KOU88_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210749.1"
                     /translation="MRLDMDSMLYVLIYMTLLVSIIGSIFYFCKDLLNHKIKYVLIRD
                     IFVNRITYSEERLPKQYIVFQKYDIWRYCSLF"
     gene            58177..58827
                     /locus_tag="KOU88_000841"
     CDS             58177..58827
                     /locus_tag="KOU88_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBK3210750.1"
                     /translation="MDFISSILQGLLSILFNFTGDFGISIVLITLIVKLVLMPLSLKQ
                     RFSVKKQQELAEKMEHIKEKYKNDTKELEKQIQVSSVESMKSMLGCLIVLAQMPVVYA
                     LYHVCLDMTKEFTTIIIPWIANLGTFDNLFILPCIYTLIMLASNLVNYIPYLKINSQV
                     KFNKQMAVVTTITSLILTVRTPVAIGLYFITSAIYSLIEDICFRIYFNRKNRIVTK"
     gene            59041..59712
                     /locus_tag="KOU88_000842"
     CDS             59041..59712
                     /locus_tag="KOU88_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004081624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210751.1"
                     /translation="MAKILIVEDEKRMQSIIVEYMQKGGYTCITADDGVEALTILKSN
                     NIDLMILDIMMPYLDGFSVCRVSREMTNIPIIILTAKGEEEDKLKGYEYGADDYITKP
                     FSPKVLLAKVNALLRRYTTDIPKNSLSLGKIFIMVASRQVYVEDKLIDLTYKEFELLR
                     LFMENPNQVFSREKLLNCIWGYDFEGNTRTVDTHIKTLRKKLGSEGHHIVTLIRSGYK
                     FEVKA"
     gene            59709..60839
                     /locus_tag="KOU88_000843"
     CDS             59709..60839
                     /locus_tag="KOU88_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3210752.1"
                     /translation="MNSLRKIIEKLKNVDISNWIKQNFGLYSVRKKVFLLSKLSGALI
                     ILFYLVVEEFSINSKFEFWIWFIILVIFIMSIDFLLGKFISEPITSINKSAKSMSQLD
                     FSNPCTVNTNDEFGELSRSLNTMSTNLQQALSDLESANIQLEKDVNKERMLLEQRKEL
                     VDTISHEMKTPLGIIRAYTEGLMDEVDEEKKKNYMNVIIEETDRMNNMIVSLLDLSAL
                     EAGVSKLNPERFDFIEFVETVAGRLLIDIPDANFYFTYDLPEYEVFVVADKMRMEQVV
                     ENLVINAKKHVVYNGNLDLSITCENGLLLFEIYNDGRFIEQDEISKIWSKFYRSVQSQ
                     RTGGSGLGLAIVSQILTMQGLEYGVNNRDRGVEFYFMIPIDE"
     gene            61271..62116
                     /locus_tag="KOU88_000844"
     CDS             61271..62116
                     /locus_tag="KOU88_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210753.1"
                     /translation="MIKVRELKFSYGKDKQILHGLNFEVKEGEIFGFLGPNGSGKSTT
                     QKILNGVLKGYNGHVSIFGKEVKAYTESLYQKIGVLFEFPYLYTNLSAIDNLEYFSSF
                     YPKNQRRDIYELLDLLEFKKEFINKPVSSYSKGMKQRISMARALVSNPKLLFLDEPTS
                     GLDPSGAVLFRKIIEEERKKGTTIFLTTHNMLDADLMCNNVAFIADGKIMVIDKPKNL
                     KMKNSNNKVEVEFVYNGNRDIEIVDIQELESGITFKYDEILSVHSKEPTLEEVFIKYT
                     GRMLV"
     gene            62116..63144
                     /locus_tag="KOU88_000845"
     CDS             62116..63144
                     /locus_tag="KOU88_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210754.1"
                     /translation="MYSKFFTLVKKDFWMMIYGKFFVLTLGSLILYSCYINFGYVKFM
                     DEDSYHNNVYLYNPENISMSASPLINQVSSIGELKAKLDEDTSAVCIDMSSSKPKVIL
                     HESIKGVDNYRADYALSLLSSEKDHNSKISDNNAIIQINDKDTSEIKQRKDMTCEILF
                     FEIVAIGFLGIASLLFKEKQMGVMRITGILPVKRSLFILSKIFAFFICDLCFTVLLVV
                     FNIGFLEGIKILPQVLVQASILSIIMSLIGIGCSMLLRDFKQFSLIYLVVAVFITTPI
                     FLSANTSFEIDWIKYHPFYHVYSQLKNAFFMNFSKELVYFVVCSLTIIVLFLLVKYIF
                     NKELVREG"
     gene            63147..64160
                     /locus_tag="KOU88_000846"
     CDS             63147..64160
                     /locus_tag="KOU88_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210755.1"
                     /translation="MIGLRYQLKSIKKDKMCIISFFLPVVMAILINFMGTIDISSLGE
                     IRFGIVKDTLPVQTEQWLKKYGMVSVYDTKMHLIREIKDIKTDTIGVVRDGKGIKTVL
                     YGNEINAIKNVGKTLPEMFRLKGDLKDVEVTILPKYSILKGFQNVFIAMILITAMFMG
                     CTFNAMNIISEKEDGISFINEVLPQSRSQYIIQKVFLGLLCGCLSSMITVFICLDISI
                     LDMIMMLLLVVFSAFISSLIGLFIGKLSEGLMVGIVYIKIVMILFIGTPLLIYLLGVN
                     TSGIGNLCYIMPSVATFNGIMEIINGNVIIIKDIVILAVHCVVWFMIYIILDKKRKLS
                     FSR"
     gene            complement(64677..65927)
                     /gene="cme"
                     /locus_tag="KOU88_000847"
     CDS             complement(64677..65927)
                     /gene="cme"
                     /locus_tag="KOU88_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Cme"
                     /protein_id="HBK3210756.1"
                     /translation="MENKNTNSTWKKKVILFLASQYISLFGSSLVQMAMIWYVTLQTS
                     SGVWVTVLTVCSFIPQMIISFFAGVWADYYNRKVLIIVSDSTIAISTLVLILFMMSSN
                     GTTSELIAISVISVIRSLGSGVQTPAVNAMIPQLVPEEHLMRFNGINSSLQSIVQFIV
                     PIVAAAILGFGNKINQVLLIDVFTAIIAIVLLIFIKIPKHDIPKQTEKVSFFADMVSG
                     IKYCFSDKFIRKVLFTYGAFMLLCVPSGFLIGLLIERTFGKGYIYLSIIEMIGFLGMV
                     LGGLIIGVFGGFKNRNKTFFLAILSYAIFSIILGLVTQAWQFFIFMFFTNFSIPIIQA
                     SAMTMLQEHVAPQMLGRVLSLPIIIYTGFIPLGMMIFGPMADVISINNLIIIAGIILL
                     FFALAIPYSKQFYKQGISKSNESE"
     gene            complement(66013..66759)
                     /locus_tag="KOU88_000848"
     CDS             complement(66013..66759)
                     /locus_tag="KOU88_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3210757.1"
                     /translation="MDTYTTSEVADLIGVHPNTVRLYEELNLIPKPKRNTNGYRIFND
                     FHIEQFRFARTALKIEVVQRGLRKDALEIVRTSANRDFDKAISLVNQYLQQLEIEKSN
                     AEEALTIVAQILNGNTPETNKLFLTRKETAEHLNVTIDTLRNWEMNGLLKVKRKQNGY
                     RVYTDEDIKRLKIISALRCANYSLSAILRMLNALSSNPNTNIKTVLDTPKDDDEIISV
                     CDKLITSLKEAEHNAKTMKSHLQIMKKQFS"
     gene            complement(66893..67915)
                     /locus_tag="KOU88_000849"
     CDS             complement(66893..67915)
                     /locus_tag="KOU88_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBK3210758.1"
                     /translation="MNKNNCLDLIFEKVDPSSVGMSSEKLSQLEPLIISQYSNINGII
                     IARKGKIVFEKYYNGYNADDTFHVASVTKSIISALIGIAIDKGYIKDVDQKVVDFFPE
                     YTCSPSEICKKAVTIRHLLTMTAPYPFKNMTESLERLCKQKDWIKYTLNQLGQKGEIG
                     TFKYSSAGTHLLSAIITKTTGKSAREFANEYLFKPIGMKVIPDYDMKDFGFEDFFGKN
                     LKGWAKDRQGYSIGGWGLTLSARDMLRFGFLYLNDGIWNNKRIISKSWIEESVKMNSN
                     EYGYLWWLCKKDGVLWYSAMGTGGNAICCIPQYDLVIAIPSKIVFKPRDRWEFIEKYI
                     LTSIID"
     gene            complement(67915..70335)
                     /locus_tag="KOU88_000850"
     CDS             complement(67915..70335)
                     /locus_tag="KOU88_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBK3210759.1"
                     /translation="MKEIKINGAKIHNLKNIDVSIPKDKLVVATGVSGSGKSSLMFDI
                     VFEEGRKQYLQSLGILAGIDSEDKFDNIQGLAPTIAVQQNIIRQSNPRSTVGTRTNIL
                     NMLTLLYSVEGQIMCTMCDTPISDNLICNNCGYEEERLRPSYFSYNSSDGMCMKCSGH
                     GAYFEINIEKLVLDKHDTLKQVLDRAKITPGYLRVFSKKFNDYLDIQFLQLPEEIRNE
                     VLYGHYENGKKSSSLSKVFHNRYKRGEDLNGVYTMTACSDCNGFKIGEEARRVLLNGK
                     HIGELGKMTILEIDDFLKLLINQGNLNTFGTNLVNDILSKTQHLIESRLGHLSLYREM
                     STLSGGEMQRLFLNSHLDSEMDSLIYVLDEPTAGLHESEKIDILKSIKKLKDLGNTVI
                     VVEHDKNTIKMAEHIIDIGPKAGVEGGQLVYQGDLEGLLQSNKSLTGQYLSGKYPMPN
                     RTSNKNITHTDKIPCITIQNANTNNLKNVTVSLPLSAMVGISGKSGSGKSSLISDTLL
                     PLLRSQFNNHTINNQINSSESEIGEEDDYAVVETIADRLIGTKHISGYSEISQSPIGK
                     NMNSTPASYIGIWDKIRTLFAGQPESLERGFTAGHFSFNSKGACPKCSGSGYEKVWLG
                     NNLSIDHICSECQGKRFNDESLSIKYKNKNIHDILNMSVSESVYFFKDIPNIVSHLNV
                     LEQIGMGYIKLGQPTPNLSGGESQRIKLAKEIGKKRNGNILYVLDEPTTGLSLYDTSK
                     LIQLLDELVENGNSVIVVEHDIDVLNVCDWIVELGPEGGDKGGYIIAEGSPKALKENP
                     KSITGRYL"
     gene            complement(70421..71341)
                     /locus_tag="KOU88_000851"
     CDS             complement(70421..71341)
                     /locus_tag="KOU88_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK3210760.1"
                     /translation="MTNAKSKKEYLNRICKVQDYIEEHLHEPLSLDELSNIAGFSKFH
                     FHRIFKAIEKETLAQYVNRLKLENATAFLIHRTDMTVTDIAHYFGFTDSAVFSRAFKN
                     YYKISPIKYRNNYSKNCKEPYKISQYNRSISKPKCKNTREVKGEIEILELDNMNTIYT
                     RYTGSYGNLTSTFPKLLERLFTYASEQNLLGLENTQILAIYHDNPQFTQEHQLRTSIC
                     MTIPDNIVVKENDNLGNMIIPSGKYLVGHFDISKSEYSDAWDFMYNEWLSNGNYKLRA
                     SFPFEVYLNNPHNHPQNRHLVDIYLPIEPF"
     gene            71951..72877
                     /locus_tag="KOU88_000852"
     CDS             71951..72877
                     /locus_tag="KOU88_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBK3210761.1"
                     /translation="MSNSFYQLNSAVLYFNEKRDVNRIRFNHYVMRKENIQRLKGTLP
                     RGQFMMTVRKAASDLDVSISTISRLVNEFIDLGILRLISRGVKGNCCSVYSYVCSESS
                     NAEIVTKNGDIFKNIEKYIDATINNNQKTMKYKHRDELFKNSNTNIYSRINQESIDKD
                     YDLIIHTGYETENETKKKELLKNNLNKKNLNKNTFENSDEDLTEDSTYKNPESIHEII
                     IRKLNNESGKNFKADLSITKALIDKRLKEGYSLEDFYKVIEAKVRRWRYTDMEIYIEP
                     TILFGYEFESYLNEESSLSACNYGDMCYEDMY"
     gene            complement(73072..73692)
                     /locus_tag="KOU88_000853"
     CDS             complement(73072..73692)
                     /locus_tag="KOU88_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210762.1"
                     /translation="MVLINILLVDDHMLFAKSLSIALEEYKEIEQFYSTQDIHNLSEM
                     IQDKKIDIVLMDINLRGLSECDGLKVAYNLLETNSTIKIIILTGYDLPVYKHEAKKIG
                     IYGFLNKNISPDSLIDSLLKVYQGGTCFPSENTEVIIEDLTTMEKRILQLICSGKKRK
                     IIADELYISERTLSNHLQHIYDKLDVSSSVEAITKAIKMGYISPVY"
     gene            complement(73664..75247)
                     /locus_tag="KOU88_000854"
     CDS             complement(73664..75247)
                     /locus_tag="KOU88_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210763.1"
                     /translation="MTNFNLKILFLGNYILSLLFMGISTSTETYMNIQSIIPLIISTL
                     LLIDITYITSCNVRENNIISLFCGLLALDSWYLLLSFVTTPIGTIIFKILSTVIVYVS
                     IKFIFLFLFQGSGYNFRKITDILLLITCIGAIVGAFISNRTYACMYGIQFVVSIISFF
                     YIIFYHLKRVVFVIKSEKKPISISVFITIIGFLTYYFFTLRISNHIGNFGIYLTVLVF
                     FMSIHGIALKENDSFPISTVFNIKQRAIFLFISILVISLVVLFANGNFSIILIAINVL
                     FMLIFLCNIILEFNLRDEKNKVVKNSKYTFALEKLQQEEQLKTEFSNFLHDDILQNLL
                     SIKNMMSKSYRPDVQDIIYETLNNLNTCIRKQMQDYHPVILKNLTVKENYQNLIESVS
                     SSFPQKNICVSFKCSDTLFLVEPYDILIYRLIKELLTNVYKHSNGSHAWIALALEKNI
                     IKLNISDNGVANTSFKTPLDITKITFDTTKHKGIISIKEQVENLGGTISVSDNIPHGV
                     CVQITIPMKGDGSYKYFVS"
     gene            complement(75391..77418)
                     /locus_tag="KOU88_000855"
     CDS             complement(75391..77418)
                     /locus_tag="KOU88_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210764.1"
                     /translation="MNIFYTAIKNLKKNFSFYSLYLLSVSFVITVFFAFTSFSVNKIM
                     LEKISTDGRVESMCNVISIFLMAFVIFYMAYSNRFFLRRRTKELGIYALLGYRKFTIL
                     SLLTFENVLICSGAFIIGLVLGALAHKGIVFGITALLNLSIDNSQIPFFNINAINKTI
                     IFIALVVLVLAVSNGKFFYKTPLVKLIRYEKSAEKKLKFRKIPAFMGFIMILSGYCLS
                     LDILRGAKSVWVSIGFYQMGLITMIIIVIGTVLFINSFLPYIMQNSKKNKRTFYTDMK
                     IIAIPNFIYRIRSNSKTLIMLTLLSATTLTVSSVMALSLYYPIASVSRIAPSEIEFRV
                     EKNKQIEDVKQIVSQYTSNTDDIIFTQTNIYKVKSSSKDLPFEYEIGTSKNNLSNSSS
                     SKEVISRESGFECISFSDYYTLLKAQNRTKLLKQLTPLRDNECILMKYQPNNDGYSEN
                     GTIYPLLVNGKETPVAVRETSLNNAISFANSVGTLIVNDSIYEQIAQNKLPMTSILSI
                     NGKSIKNNENLYSNISDYLDGSPYLQGYSHRINDLLSINSSTFLLIGFLVVLFFIAVG
                     SILYFNNISAISDSTSDYKILQKMGYDNIQIKKIIKKQVLPFFNIPFLLGILDCIFAT
                     LVYKTALMQNLLGNSFSQYIPVIIAIFLTSVVYLIYYILTIKSCCKIVLKN"
     gene            complement(77431..78180)
                     /locus_tag="KOU88_000856"
     CDS             complement(77431..78180)
                     /locus_tag="KOU88_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005340256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210765.1"
                     /translation="MNTILKVNNITKTYNKGQQPSLDKVSFNVSEGEFIGIMGASGSG
                     KTTLLNVLSTIDKPTSGDIFINNINLKSLNDTCAADFRKDNLGFIFQEYFLLDSLTIF
                     ENISVPLTLQKLNPDKIENMVKSLAERFGIASQLNKYPNELSGGQRQRASAVRAIVKH
                     PSILFADEPTGALDSNSATELLHSLQEANEELKTTILMVTHDAYVASFANRILIFKDG
                     HIIKELNKQQNNRHTFYELIIQEIAKLDTKR"
     gene            complement(78479..80131)
                     /locus_tag="KOU88_000857"
     CDS             complement(78479..80131)
                     /locus_tag="KOU88_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp21"
                     /protein_id="HBK3210766.1"
                     /translation="MNKKNLAILISGMMFFSSSSAIFADNTTNQERLIGKTRYETAVE
                     VSKLGWVQSKTAIIVNGNSIQSALCANPFAKLKNAPILLVNNNSIENSTKAELKRLGV
                     DNVYIVDSGNSISSKVENEIKSLNIKINKIVGNNIYEMSTNVLKEIDKIKKVENVAVV
                     NGLKGLSDAVSIASPAAIHNMPIILVSDENSNDSSINFLNNRSIKKSYIVGGNKILSD
                     NTVKKYPNRERISGSDRNNTNAKIIDKFYKDKKINNVFVAKDGINQENALVDSLSIGV
                     LAAKENSPIMISNGSLVNSQKEFIKNKDIDEITQVGGGYNQKAFEDILKLKNVNIRNK
                     TKKISLIQAKEILKQALPGSNILVCYYDEDDNEYDCKVIKDNILYEIEIDAYSGKIIE
                     IEKDDDLNDNNLGTQNISLDKAKSIALDAIPNGNLIYCKYDAEDNEYEAKVIKNKKTY
                     ELEISAFDGRIVDIDMDNDSDDDFDDNDKNNSNTNDNSSIISAEKAKSIMLDKVPGGK
                     IVKFKYDEDDKEYEGEIIKGKTEYEITINAITGKILEFEIDD"
     gene            80730..81851
                     /locus_tag="KOU88_000858"
     CDS             80730..81851
                     /locus_tag="KOU88_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK3210767.1"
                     /translation="MEAKKLGFGLMRLPIKDENDVTTIDMEHLNKMVDTFLERGFTYF
                     DTAYVYHMGKSEIALRESLVKRHKRESFTIATKLPLMALKKKEEQETIFNEQLEKCGV
                     DYFDYYLLHNIGVSHYEVAKKFDSFKFIEEKKKEGKIKNIGFSFHDSAELLDKVLSEH
                     PEVDFVQLQINYLDWDNESIQSRKCYEVAEKHNKPVIVMEPVKGGTLAKIPEKAEKLL
                     NDYNPDMSISSWAIRFAASKDNVMMVLSGMSNMEQLLDNTGYMQNFKPFVQEEYNIID
                     EAVEIINESILVPCTACQYCVEGCPKNIAIPNYFALYNAEKQALNTGFSTQMVYYNNY
                     TKTYGKASDCIECKQCEESCPQHIKIIDALKNVAETFEK"
     gene            81887..82300
                     /locus_tag="KOU88_000859"
     CDS             81887..82300
                     /locus_tag="KOU88_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3210768.1"
                     /translation="MTISEVSKKYELSADTLRYYERIGLIPPVNRNKSGIRSFTEEDC
                     EWVNFIKCMRGAGLSIETLIEYVAMFQQGSSTIKARKELLIEQRNQLAKRIEEMQKTL
                     ERLNFKIDRYEEGIIEKEKVLKSSRNKKMEAVSYE"
     gene            82293..82832
                     /locus_tag="KOU88_000860"
     CDS             82293..82832
                     /locus_tag="KOU88_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3210769.1"
                     /translation="MSKNVLIVSASPRKGGNSDLLCDQFIQGVLESKNQVEKIFLKDK
                     DINYCTGCGACYEKEANCSQTDDMGEILEKMIGADVIVLATPVYFYTMNAQMKTMIDR
                     TCSRYTEICDKDFYFIVTAADENVADMERTIEGFRGFTSCLNGSKEKGIVYGVGAWNV
                     GDIKGSKAMKQAYEMGKLA"
     gene            complement(83020..83505)
                     /locus_tag="KOU88_000861"
     CDS             complement(83020..83505)
                     /locus_tag="KOU88_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210770.1"
                     /translation="MSKSELTAETTEEMLEVLSGKDYDIACHLHELGKSLDCKIEPKT
                     GARSYKIVYSTKKPKRSLFTIECNEKKWRVKANLFHLNTYKDAVEECSKTIKDSITKT
                     RTCKKCNSKCIGGSSFELDGKSYLTCIGSGHYFANMEEMDWKNLEKLITKENNIMQES
                     V"
     gene            84410..84787
                     /locus_tag="KOU88_000862"
     CDS             84410..84787
                     /locus_tag="KOU88_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003483933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBK3210771.1"
                     /translation="MSKVVIATEKAPGAIGPYSQAIQVGNIVSTSGQLPIDMKTGELV
                     SDPKEATKASLDNVKAILEQAGTSMDKIFKTTVFVKDLKDFNDINEVYATYFKENPPA
                     RSCVQVAQLPKDAVLEIEAMAVL"
     gene            85183..86988
                     /locus_tag="KOU88_000863"
     CDS             85183..86988
                     /locus_tag="KOU88_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3210772.1"
                     /translation="MLSKLKEFQQEMIKYTETVASVLDVDIEIVDDRLIRISGTGLYK
                     SKINESVVTEGFIYDNVIQTGQELVVLDICDNQLCIECSHYMKCLNKVIIAVPIKYNN
                     RTIGVIGAISTDKTKKVEISAKIDNYLKFVNHICDLISMKIEEHEASKNSSRKMDMMI
                     EIIENVEKGVIILDINSKISYINNIALKKLDIDKNIIENIVNIVSVESSSNGHELLEI
                     DIDNKIYNINAKIIPVYPYINQYDKIIIFDKTYINHKGHGKVNSGWGNSDIESIIGNS
                     EAMLKVKERTKKLAKSNSTVLITGESGTGKELIARAIHAEGSRWNKPFIAINCAAIPE
                     NLLESELFGYIKGAFSGASSGGKVGKFELANEGVIFLDEIGDLSMPLQAKLLRVLQER
                     KFARIGSNKLIDLDIRVIAATNKNLLKLVNEGKFRDDLYYRLNVIPINLPPLRERKDD
                     IEAIMMKFASKYSLELGIQLNKIEENVMNMLINYNWPGNIRELENAVEYMMNLVGDDG
                     IIYKDMLPLDILNYYNINGNIYKNKDVNIIFEDDIVGGIVENQERILSIKELELTYIN
                     KLLNKYGRDTKTKKKIAKDLGIGLATLYRKLEEEQ"
     gene            87065..87604
                     /locus_tag="KOU88_000864"
                     /pseudo
     CDS             87065..87604
                     /locus_tag="KOU88_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427977.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="2'-5' RNA ligase family protein"
     gene            88227..89441
                     /gene="dpaL"
                     /locus_tag="KOU88_000865"
     CDS             88227..89441
                     /gene="dpaL"
                     /locus_tag="KOU88_000865"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBK3210773.1"
                     /translation="MREIKWKLNNLPKSEEKEKGIEFLKDEEIAKAKAFHESFPQYEK
                     TPLVKLDNLAKSLGVSGIYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAKEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNYSSAFVSAPDWVSAKGMRILGNP
                     LRGDEKVISGESGAVTTGALVSILESEDLKDLREALKLDENSKVLLISTEGDTDPDKY
                     RDIVWNGECQSK"
     gene            89791..90978
                     /locus_tag="KOU88_000866"
     CDS             89791..90978
                     /locus_tag="KOU88_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBK3210774.1"
                     /translation="MLNETRKKQLTEVCQDLIRNASYSGQEENVVKAIEENFALLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEARIVDGKIYGRG
                     TSDMKGQVSAMMAAVSYFAEDTNKDFEGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGINAVYKMANVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIRTIGFGPSKENLAHTIDEYIELDQLFKGAEGYYGILKSV
                     YKK"
     gene            90994..92577
                     /locus_tag="KOU88_000867"
     CDS             90994..92577
                     /locus_tag="KOU88_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBK3210775.1"
                     /translation="MRTLIKHGLIVDGNKTPAYEGDILIENEKILKISQDLNEEADKV
                     IDAKGRVICPGFIDTHSHSDLVILVNPYNEVKIRQGITTEVLGQDGISMAPLPQEHIS
                     SWRKNLAGLDGESDEIDWKYETTENYLKMMDYNGVGLNETYLVPHGNVRMEAMGLEDR
                     PATKEEIQKMCEITERELKAGAIGLSTGLIYIPCAYSLTEEIIEMCKVVAKYDGVFVV
                     HQRSEADTILTSMEEIIEIGKQSGVKVHFSHFKVCGKANWKYIPQVIELLEKAEKEGI
                     RVSFDQYPYAAGSTMLGVVLPPWAHSGGTDKLIERLSDENERAKMKKDIANGIEGWDN
                     FIEFAGIDQIFVTSVKTEKNKDTIGKSLLEIGKMRGKDPLDATFDLLKEEENAVGMVD
                     FYGLEEHIIGFMKRDEQNVCTDGLLAGKPHPRAYGSFPKILGRYVRELNVLTIEEAVY
                     KMTKKAATSFSIKDRGELKEGYFADIVIFDKDTVSGCDDFINSMQYPTGIDYVIINGN
                     CVVEEGKYNKIKAGKVLKN"
     gene            92605..93933
                     /gene="ssnA"
                     /locus_tag="KOU88_000868"
     CDS             92605..93933
                     /gene="ssnA"
                     /locus_tag="KOU88_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBK3210776.1"
                     /translation="MILVGNGRLISQDSLNPYMEDGCVVINDNLIEDIGTTEEMKAKY
                     PVHEFIDAGKKIIMPGLINSHMHIYSSFARGMAVPGKPSENFLEILNNLWWRLDKQLT
                     LEDTKYSAYATYIECIKNGVTTVYDHHASPNAIEGSLFTISDVAKDLGIRTCLCYEVS
                     DRDGGNTIQQGINENVNFIKYAQKDDTDMIKGMFGLHAAFTLSDDTLNKCASEMAGLD
                     TGYHVHVAEGLADLQYNVDKYGKRVLERFNDFGVLKEKTIAVHCIYISAEEISLLNKT
                     NTFVVHNPESNMGNAVGCSPAIELLKRGVTVGLGTDGYTSDMFESLKVANIIHKHHLK
                     DLRVGFEESQTMLFDNNRKIAKAYYKNDLGVLKKGAYADVIVVDYIPHTPLTENTIGG
                     HTIFGMSGRSVDTTIINGKVLMKDRKLINIDEESILAKSRELSQNLWNRI"
     gene            94078..95430
                     /locus_tag="KOU88_000869"
     CDS             94078..95430
                     /locus_tag="KOU88_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBK3210777.1"
                     /translation="MSRDKSPKIAPVDERLPVSKSWVFSLQHVLAMCAGAVAVPMMIG
                     SAARLDHASIVFLINACLFMAGIGTLIQSVGIGNIVGAKIPVIEGTSFAAVAGMTAIA
                     SSYSDSQVAIQTVFGSVIVAGLFCILLAPVFEKLIRFFPSVVTGTVVMVIGISLFPVG
                     IKWITDNKLEAVEPNSLALALAVLAITLLSFKFLKGIWNSTAILVGIVLGTLLSMAVG
                     MADFSAVNGVGWLNLNVPLKFGMPRFEPSAILSLCLIMLVLMTESVGNMIAIHEMVDK
                     EVTGKNIKRGLFGDGISTALSGIFNSFPITPFGQNTGIVGLTGIKSRFIAVYAGVILL
                     VLGFLPKFAAIIGAIPKPVLGGVGFAMFGMVMVGGVKTLSKVKFDGTKNGVIVAVSVG
                     LSMIPLTNPDFYHNFPTWVQTIFHSGITTGSLSAVLLNIFFNELGSKKEKNNKVEEAK
                     "
     gene            95622..96731
                     /locus_tag="KOU88_000870"
     CDS             95622..96731
                     /locus_tag="KOU88_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3210778.1"
                     /translation="MANLKVNLYGMEFLNPIMTAAGPGAKDGALCQEAAKGGAGAICT
                     KTISVLPADVPRPCMAKTNSGFLNTELWSELPKEQWIEEEYKKVKETGLPVIVSMGYS
                     AEQIAEVAPLVKPYADAVELSTHYVGTDVAPIVNALKAAKAVLDVPVFMKMSPHTDIQ
                     TIAKAVEEAGADGLVMINSFGPCMAIDVNTGYPIMGSKAGYGWLSGAPIRPLAIRCIY
                     EASQVVNIPIIGVGGITCGKDVAEMMMAGASAVQVCTEAILKGPSIYGKIAKELNEFL
                     DENGYADVNEIKGLTHKKMAARGFRTHSVAPVVDDNKCIKCKQCVTSCVYEALEVTDK
                     LNIDADKCFGCGLCVTRCPKGALSICYNQVEAMNE"
     gene            97014..98405
                     /gene="hydA"
                     /locus_tag="KOU88_000871"
     CDS             97014..98405
                     /gene="hydA"
                     /locus_tag="KOU88_000871"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBK3210779.1"
                     /translation="MGIVLKGGKVVTSEKTYCADVRIEDEKIVDIGLDISKENDEIVD
                     VSDSYVIPGGIDTHTHFDLDTGVTKTADNFETGTKAAIVGGTTTILDFATQAKGCSLK
                     DGLEEWHEKAKDKSYSDYGFHMAITDWNDSVCNEMEDMVKEGVSSFKLYMAYKGSLQV
                     DDGVIFEALRKAEEIGGIIGFHCENGDIICELVDKAKSENNLSPKYHQLTRPAIMEAE
                     ATSRLMKIAEVANSKVYVVHLSCKESLEEVLKAKQRGVDVIVETCPQYLLLNDELYDL
                     DGFESAKYVMSPPLRNKENNEILWNAILDNQIDTIGTDHCSFNYKGQKELGINDFSKI
                     PNGSPGVEHRMSLLYTYGVCKNKISINKMVEVTSTNAAKLFGMYPNKGTIEIGSDADI
                     LVLNPNKKSKIEAKKQLQNVDYTPYEGYEVDCQIEHVYLRGKEVVRDGELICNTPSGR
                     YINRRLTKGAREW"
     gene            98399..100960
                     /gene="xdh"
                     /locus_tag="KOU88_000872"
     CDS             98399..100960
                     /gene="xdh"
                     /locus_tag="KOU88_000872"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium-dependent xanthine dehydrogenase"
                     /protein_id="HBK3210780.1"
                     /translation="MVEFILNGEKVVAKEGKKLLDFLREDMNITSVKNGCSEGACGTC
                     MVIIDGKATKACVFKTDKLAGKNITTIEGLSERERDVFAYSFASQGAVQCGFCIPGMV
                     ISSKALIDVNNNPTEDDIKKALKGNICRCTGYVKIIKAVDLAAKIFRENIDVPKVNCK
                     GLVGENLPRVDAVGKALGYSEYVDDMRIEGMIYGSAVRAKYPRALVKKIDIEEAKAYP
                     GVVAVLTAKDIPGTIKVGHLKKDWDTLIPEGEITRYLGDGIVLVAAETREALEEAKKL
                     VKIDYEELTPLSTTADALREDAPKIHETGNILVKEHLVRGNAKEKIENSKYVVTKRYT
                     TPATEHAFLEPECAVAGPYEDDGVIIYSTDQGVFATQHECADMLGLPYEKVRVINKMV
                     GGGFGGKEDMSVQHHAALLAYHTKRFVKVQLTRKESIIVHPKRHATEMEFTTACDENG
                     YLTGMKATIISDTGAYASLGGPVLQRLCTHAAGPYNYQDIDITGTAVYTNNPPGGAFR
                     GFGVTQSCFATECNLNLLAEMVGISPWEIRYKNAIRPGQVLPNGQFADEGTAMAETLE
                     AVKEEYEKHPRAGIACAMKNSGVGVGIPDVGRCRLVIKDGKVHIRTSASCIGQGLGTV
                     MTQVVCETANLLPENIVHEVPDTHLTPDSGNTTASRQTVFTGEATKVASNKLKEALDS
                     GKTLLDLEGEEFYGEYESITDKMGCDKENPVSHVAYGYATQVVILDENGKLEKVVAAH
                     DVGRAINPISLEGQIEGGVVMGLGYALTEDYPVVNSIPTAKFGTLGLFKSTDIPEIQA
                     LIVEKNKDLLAYGAKGVGEICTVPTAPAVQNAYYVFDKEFRTELPLQNTPYSKKK"
     gene            101112..102458
                     /gene="rpoN"
                     /locus_tag="KOU88_000873"
     CDS             101112..102458
                     /gene="rpoN"
                     /locus_tag="KOU88_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBK3210781.1"
                     /translation="MNFNNSLELTQSQKLIMTTQLKQSLSILNMSKLELEEEIKREAE
                     NNPLVEVEKSGEINWEEYIKDMDRSRRLDRTEISYNPDNEVNLENLVKYSSNLYEDLK
                     FQISLYKLTDKELEVCEYIIDSLDEDGYLRTEEKVIVDTLKIDEELFEKCLISVQQLE
                     PSGVGARSLSECLMIQMASLGIYNEILEEIVTKDLNLIANNKYKEISKKYNMSLQKCV
                     ELINIIKTLDPKPGRTCSVEKSVYIQPDVTVEKIDDEFIVYLNEKDSYQIRINSYYKD
                     ILKNSQSDESAKEFIKERLNSATGLMKNIESRKTTVLKIAEEIVKAQDEFLRKGTKYI
                     KPLKMKDIAEKLEFHESTISRGVNGKYMLTPFGVYEFRYFFSSAIETENNEMASSTSI
                     KKIIKETIKDENKKKPLSDDHISKLLKEKGINVARRTVAKYREELGIPSSSKRKEY"
     gene            103240..104262
                     /locus_tag="KOU88_000874"
     CDS             103240..104262
                     /locus_tag="KOU88_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK3210782.1"
                     /translation="MKNLLEIQKKLIPQAIELMERRYSILRQISLSEPIGRRTLSNVL
                     EISERIIRSETEFLKEQGLIDVAVSGMTITKEGSDLLDKLKDIMSDIMGLSKLQDRVR
                     EKLGIKRVILVPGSCDENGSLLKDVTRYGCEYFLGILKDGDIVSITGGSTMLEFSNVI
                     KTDKRYPNSTIVPARGSMGTDVEMQSNNIVASISKKLHSNCKLLHIPDELDESAMKTL
                     SQVPEIKTTLEYIKRTDILVFSIGRADVMAKRRKLPEDKVDEILSKNAVGEAFGYYFN
                     KDGEIVYKLNTVGIDLETVKQVKETIAIFAGTEKVEALLAISNMHKNMVLVTDEESAY
                     KILSLL"
     gene            104322..105329
                     /gene="gap"
                     /locus_tag="KOU88_000875"
     CDS             104322..105329
                     /gene="gap"
                     /locus_tag="KOU88_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBK3210783.1"
                     /translation="MVKVAINGFGRIGRLALRKMMEQQDKFEVVAINDLTDAKMLAHL
                     FKYDTAQGRFNGEIEVKEGAFVVNGKEIKVTAERNPADLPWAELGVDIVLECTGFFTS
                     KDKAEAHIQAGAKKVVISAPATGDLKTIVFNTNSDILDGSETVISGASCTTNCLAPMA
                     KVLNDKYGIEKGLMTTIHAYTNDQNTLDGPHPKGDLRRARAAAGNIVPNTTGAAKAIG
                     LVIPSLKGKLDGAAQRVPVVTGSITELVCTLGKNVTVEEINAAMKEASNESFGYTEEM
                     LVSSDIIGISYGSLFDATQTKVMEVDGKQLVKVVSWYDNEMSYTSQLIRTLGYFAQLA
                     K"
     gene            105551..106753
                     /locus_tag="KOU88_000876"
     CDS             105551..106753
                     /locus_tag="KOU88_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBK3210784.1"
                     /translation="MSMLNKKTIEDIDVCGKKVLVRCDFNVPLQDGVITDENRLNGAL
                     PTIQYLISKGAKVILCSHLGKPKGEAKPELSLAPVAKRLSEMLGKEVVFAADDNVVGE
                     NAKKATEKMENGDVVLLENTRYRKEETKNEENFSKELASLAEIFVNDAFGTAHRAHCS
                     TVGAGEFLQERVCGYLIQKELKFLGEAVANPVRPFTAILGGAKVSDKLAVINELLEKV
                     DNLIIGGGMAYTFLKAQGYEVGTSLLEIDKVEYAKEMMEKAKNKGVNLLLPVDVVMAD
                     HFAPDATPIVTEDANVKEDYMGLDMGPKTIANFVKTIKESKTVVWNGPMGVFEFENFA
                     NGTLSVARAMAELTDATTVIGGGDSAAAVNQLGFGDKMTHVSTGGGASLEFLEGKELP
                     GIAALDNK"
     gene            106779..107522
                     /locus_tag="KOU88_000877"
     CDS             106779..107522
                     /locus_tag="KOU88_000877"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBK3210785.1"
                     /translation="MRKPIIAGNWKMHKTIKEALEFVNEVKDKVNSDKVEAVICAPFT
                     LLKDLKEATKGTNIKIGAQNMHFEEKGAFTGEVSPLMLKEIDMDYVVIGHSERRQYFN
                     ETDETVNKKVLKALEVGIDPILCVGETLEQREAGKTKDVCKVQVEKALENVLKDDLAK
                     VVVAYEPIWAIGTGKTATAEDANDVISYIREVIKGLYGELANEVRIQYGGSVKPSNVA
                     EIMGQSDIDGALVGGASLASNDYLDLVNF"
     gene            107531..109063
                     /locus_tag="KOU88_000878"
     CDS             107531..109063
                     /locus_tag="KOU88_000878"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003228330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBK3210786.1"
                     /translation="MMKKPVALIIMDGFGYNKDVKGNAIAESKTPNLDRIKKEYPNTL
                     INASGLDVGLPDGQMGNSEVGHTNIGAGRIVYQDLTRITKSIKDGDFFTNKVLCEAMD
                     NAKENSLHVMGLLSDGGVHSHIDHLKAIIKMAKDKGVQKVYVHAFTDGRDTDPQSALE
                     YAKEVQASMDEIGVGEFATVSGRYYAMDRDKRWERVELAYNAMVRGIGEKANSIEEAI
                     QNSYDDGKNDEFIMPTVIMKDDKPVGSIKENDSIIFFNFRPDRARQITRALVCEEFDG
                     FKREDIKNFFVCLTEYDITIENVHIAFGPQSLANTLGEYLAKNGKTQLRAAETEKYAH
                     VTFFFNGGVEEPNKGEERLLIPSPKVATYDLKPEMSAYELTDKALDKLGEDKFDFIVL
                     NFANPDMVGHTGSIEAAIKAVETVDTCVGRLIDKIVELGGSAIITADHGNAEYMLDPE
                     TGKTVTAHSINPVPFIVVGQEYESAKLLDGGRLSDIAPTILDMMKLEKPEEMTGHSLI
                     SK"
     gene            109651..110943
                     /gene="eno"
                     /locus_tag="KOU88_000879"
     CDS             109651..110943
                     /gene="eno"
                     /locus_tag="KOU88_000879"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBK3210787.1"
                     /translation="MSVIELVYAREVLDSRGNPTVEVEVVLEDGAMGRAIVPSGASTG
                     AFEAVELRDGDKGRYLGKGVETAVANVNEIIAPEIEGMDAFDQPAIDAIMIELDGTPN
                     KGKLGANAILGVSMAVARAAADEIGLPLFQYLGGVNAKQLPVPMMNILNGGEHADNNV
                     DVQEFMILPVGACCFKEGLRMGAEVFHSLKKVLGEKGLACGVGDEGGFAPNLGSNREA
                     LELIVEAITKAGYKPGEDVMLGLDVAATEMYNKETKKYVLAGEGKELTAAEMVALYED
                     WSNNFPIITIEDGLDEEDWDGWKLLTEKLGNKLQLVGDDLFVTNTERLEKGIENGVAN
                     SILVKVNQIGTITETLDAIEMAKRAGYTAVISHRSGETEDSTIADLAVAVNAGQIKTG
                     APSRTDRVAKYNQLLRIEEMVGEQARYCGLKSFYNLKK"
     gene            111536..111760
                     /gene="secG"
                     /locus_tag="KOU88_000880"
     CDS             111536..111760
                     /gene="secG"
                     /locus_tag="KOU88_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBK3210788.1"
                     /translation="MSNILMGVQVVLGILLVISIMPQDSKNALPSEFGGEGSQAYFKP
                     KGKQAFLARVTKITAVLFFINALALLIVKK"
     gene            complement(112144..113082)
                     /locus_tag="KOU88_000881"
     CDS             complement(112144..113082)
                     /locus_tag="KOU88_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBK3210789.1"
                     /translation="MENLILSINVVLPLFLTMSLGYVLKKLGLFDTHTLNKMNNVCFK
                     SFLPLLLFFNIYNTDLDGSLNFKLMAVAVIIIFSIFLILVFIIPKIEKDNKTRGALIQ
                     GVFRSNFVIFGIPVTISLFGDKSIGVTSLLIAVIVPMFNVLSVVILEIFRGGKVNIKH
                     MIKSVLTNPLIIASFIGLTMLILNINIPTFLHKTIGDISKIATPLSLIILGGSFSFSA
                     IKGHINPIILGVCGKLILVPAIFLPISIFLGFRNVELASLMIMLSAPTAVSSFTMAQQ
                     MDSDSELAGQIVVFTSGFSIITVFLIIFILKQNNLI"
     gene            complement(113070..113468)
                     /locus_tag="KOU88_000882"
     CDS             complement(113070..113468)
                     /locus_tag="KOU88_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK3210790.1"
                     /translation="MIKKIEHVVITNNNIENYINFYKKFGFSSKEMSKNYKLNARNVK
                     INLNIKGYKFLPYVKNSKASRDNLCFKINTNIDEPKKYLEQNEIQIERGIVECTGVFG
                     NMKSIYLKKTNGNLIELSNHRITESKPWKI"
     gene            complement(113968..114465)
                     /locus_tag="KOU88_000883"
     CDS             complement(113968..114465)
                     /locus_tag="KOU88_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HBK3210791.1"
                     /translation="MKVTSTGIVNGVIEDKYGKRGTQFNEGGMPTYSLPLKFEDAPKN
                     TVSFAVFLEDKDSVPVCGFAWIHWLAVNITKDELNENESVTATDFVQGTTSWHGKLGG
                     LDRLEASVYGGMAPPDRPHVYEIHVFALDTILDLEKGFYMNEFFKAIEGHVLDTFTLK
                     GSYSN"
     gene            complement(114571..114933)
                     /locus_tag="KOU88_000884"
     CDS             complement(114571..114933)
                     /locus_tag="KOU88_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210792.1"
                     /translation="MKLRDEYTCPLELTHDMIKGKWKSIILWRLRIGPTSLSKLEKEI
                     NGINQKMLLEQLKELIEFGLVDKKTYEGYPLKVEYSLTPIRGKQILDALAIMQDIGIS
                     FMLDNGMEDILKEKGVLK"
     gene            complement(114951..115565)
                     /locus_tag="KOU88_000885"
     CDS             complement(114951..115565)
                     /locus_tag="KOU88_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBK3210793.1"
                     /translation="MEEVIAKIITIENGFKEIENIAKKIVKNNDSKKCYYLSIYLYRS
                     EYYQVRELAVFILGFISVTISEALLFLKDNVSKDENWRVQEILAKSFDYYCSEVGYEK
                     ALPVIKEWLNSDSPNIKRAVTEGLRIWTSRDYFKSNPDVAISLLSSLKEDGSEYLRKS
                     VGNALRNISKKYPDLVKKELDSWDISNKKVEFVYKLASKCILAK"
     gene            116161..118296
                     /gene="rnr"
                     /locus_tag="KOU88_000886"
     CDS             116161..118296
                     /gene="rnr"
                     /locus_tag="KOU88_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBK3210794.1"
                     /translation="MIPGLKESLLGLINESAYNPLKKEELAEIFDIHSSEMPMFYNFL
                     NELEEDGYICFTKKGKIVSPNQMGYFVGKFVSHKKGFGFVESDVEYTQDLFISSDNIN
                     GAMHNDRVMAEIVVPATEEKRAEGRIVKVIKREITRIVGTFQSSKTFGFVTPDNKKFT
                     KDIYIPKKHFSGAVDNDKVVCEITVWPQEDRKPEGKIIEILGQKGERGVEIDSIIREH
                     GLPEEFPKKVLQEAEAVAVEIPQEEIKRRRDLRDLNIFTIDGDDAKDLDDAISIEVLP
                     NGNFKLGVHIADVTHYVREKNKLDKEALKRATSVYLVDKVIPMLPKTLSNGVCSLNPF
                     EDKLTLSIFMEIDHKGNVVKHEICESVINSKARMTYTEVSDILEKDDEKLKKTFEHVV
                     EDFKNAEILARILMSRREKRGAIDFNFPEAKIILNGKGEVVDIKPYERRISNKIIEEF
                     MLISNETIAEHFYWMGIPFVYRIHETPSLEKMEELSKFISTFGYIIKGDKEEVHPKAL
                     QGIIEKIKGKKEEGAISTIMLRSLKQAKYSPECSGHFGLAAKFYCHFTSPIRRYPDLQ
                     IHRIIKESLNNKISGKRQEQLTTIVDYASVQSSEKERKAELAERDVHDFYKALYMKDK
                     VGQEFEGVVSSVTSFGIFVELDNTIEGLIRLANMNDDYYIYDESSYSVLGERTKKSYK
                     IGDLVKIKVESVNVDFKEIDFEIVEKIEE"
     gene            119476..119967
                     /locus_tag="KOU88_000887"
     CDS             119476..119967
                     /locus_tag="KOU88_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBK3210795.1"
                     /translation="MGMIGCYTKISEENVFKLQQAEENLQDFVFEDANENSTINIDKA
                     WHAIHFTLTGCPFGGDDDNIFSKLVLSGNILMEIDGEFPVMLITANDVKKLSKAMNSL
                     EEQAFRKRFNINEMLENNIYPVMNDESEDDFFEYVWANLIELKKFIQEASNDGLAVIF
                     FIM"
     gene            120495..121367
                     /locus_tag="KOU88_000888"
     CDS             120495..121367
                     /locus_tag="KOU88_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210796.1"
                     /translation="MEMKIAVSNLSKRFGKKQALDNINLEIDSGMFGLLGRNGAGKTT
                     FMRILATLLSKTEGSIHMCGVPIENTKEIRNMVGYLPQDFSMYPNMTVYKAMDYLAVL
                     SDIPLRKRRKIIAKLLSKVNLTNYQNVKVKSLSGGMNRRLGIAQALIHNPRVLIVDEP
                     TAGLDPEERIRFRNLLCEIANDRIVILSTHIVGDIEATCENVAILNSGKVIYNGSTEA
                     LAKLAEGKVYSIEVDKKDIENIKSRFIVIGMLTHGGKAILRIISDDKPFETAVNCNPT
                     IEDGYMLIMGGDNI"
     gene            121364..122653
                     /locus_tag="KOU88_000889"
     CDS             121364..122653
                     /locus_tag="KOU88_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210797.1"
                     /translation="MNLFIKECKNILKSMVYYIFIVVLVFFYISQLGSSVSNDVSKNI
                     PNDGNPLVAPQKVENIEEYYSVHNQYPYGQKESMKTEKVIPNATINLIREYQKNTYTT
                     YPTGVVKYIKLDQNKTKTIEKYIEEITGKSISEINSLWKTDESIKIDYSKVSLERFEE
                     IMQRVDHILGGGSAYAFDKLQRFGVVPVTYDEAMKNYNYTIQKDKVSNGYARIFCDYI
                     GIVLSIFPVFVAVFMSLKDKRSRMREIIYSKQVSSCKIVLSRYFALVFMMILPVLILG
                     MKDLLPLIFFAKDKGISIDNLAFIKYTLWWILPTLMIVTAVGMSITILTDTPVAIIVQ
                     LIWWLYSINSTGLKGDYSTMGLMIRHNSVLNGDIIIQNFNQIMINRIVISLEALVLVL
                     LAIFLYEQKRRGNLDVWAKFSKLFSSNKRKLQIKHFN"
     gene            122583..123227
                     /locus_tag="KOU88_000890"
     CDS             122583..123227
                     /locus_tag="KOU88_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210798.1"
                     /translation="MFGQSFQNCLVLIKENFKLSTLTNLICSIILLCMIPLIQGVANL
                     DRISTAICLENYVAIIGIVMLVPVFSLEQSKEIDEIVSSKALSQVIVQLIRILMSIIG
                     IVVLIIGFVNVLIYLGCNFPVVEYIIGSFASAMFIGSLGMFFSNLFNNTIIGYMISIG
                     YLILNMMTKGKYVGKFFIMSMSQGSFDEKYWLILGSVVLIIASLLIKPVKRKIR"
     gene            complement(123494..123958)
                     /locus_tag="KOU88_000891"
     CDS             complement(123494..123958)
                     /locus_tag="KOU88_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3210799.1"
                     /translation="MNLNKVKFTEEHAIEVTNWKYEGKYSIYNLPPWEEIKKKNFSLA
                     KEDKRKNFISFINDNKELIGFINLLDEGSSVFFGIGMKPNYCGMGIGKEIISLRLQEC
                     RNKYSTKPIVLNVRTWNMRAVKCYESQGFKIVETKVQKTHLGDGEFFVMRYQ"
     gene            complement(124973..125800)
                     /locus_tag="KOU88_000892"
     CDS             complement(124973..125800)
                     /locus_tag="KOU88_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBK3210800.1"
                     /translation="MDLSKKVKILENASDGKSEFEILEFEKLEGASSPLMAMGLYFAR
                     EAGLKARQIKIKLNNSSIKTEAGALYYYKGNISSETKIGGVGGLFKKGISGALTNESM
                     MKPVYKGTGEVYLEPSFRHYLFMSLDNDSIIVDKGLFYCCSDTIEVKAFTQKNFSSAL
                     LGGEGFFQIELSGTGVIVLECVVPQSEIVEYELKNGEELKVDGNFAIARTSGVNFSVT
                     KSDKSLIGSALNGEGFLNTFTGSGTVWLAPTQVMYEKLSFGAMPTNDNMNNKVSKQK"
BASE COUNT        48417 a        15019 c        21499 g        41104 t
ORIGIN      
        1 tacaagggga ttgtctaata aaaagataat ctcctttttt acaaataatt ctaaattgtg
       61 atataaatct aaaaatttta tcttaacatt taaccattta atgataataa ttgatataat
      121 aaatataaat taaatatatg gtgtacttat tttatgtttt tagcaagaaa tatagcattt
      181 aaaagataaa ttgtgcaact taaatcaaag tttaagatga actattaaca tagatatatt
      241 aaaaactttt gtaatggaga atatatgtga tatgaataat aaagttaagg ttgcagtatt
      301 agatacagga atagacaaag aacatgatta cttaaaagat aatttagttg gaggaattgc
      361 ttttgaatgt atgcatgatt atatctttat atcagataaa tttgatgatg aagatggtca
      421 tggaactgct tgtgcatcaa taataaagaa agagtatgaa gatgtagagt tatttgtaat
      481 aaaaattttg agaaaagatg gtattacaaa tataaaagtt cttgaagaag cattaagata
      541 ccttttagac actaacataa gattaattaa tttaagttta tcagtcatag gagtagaaag
      601 tgttaagggc ttatttgaag tttgttatga attgtttaga aaaggaaaaa taatagtatg
      661 ttcactcgct aatgattttg acttaagtta tccagctatg tttaacaatg ttataggtgt
      721 aagaggattt actttagatg gagatgattc attttggtac aacaaaaaat atgatgttca
      781 atgtgttatg gatagcaatt catatataag ttgtgatata aataattcct atagattacc
      841 accaaaatgt aatagttatt tatcagcaaa gcttactggt aaaatagcta agatattatc
      901 agaaaaacca ggcataacaa tatctgattt aaatgataag cttgaatcat tagcaactag
      961 aaatcattgg gatagttgtg attttgatga gtgtagtaga attgtaaact ttaaattgga
     1021 tttgtatgac aaagaaaatg ctcttcttat gaaagttgct gacgttgtta gggattgctt
     1081 agatattgaa gataataatg aaaaactctt taagggtagc ctttttaata aggagatagg
     1141 cttggtttat gataattgtt ttaatctgtt gaaaaagcta gagcatagat ttgacataaa
     1201 gtttaattat atggacatct caaaatatga cttagtttca atatatacac tgactgaatt
     1261 agtggaaaga tataaaaact tataaataaa gatttgtagc taaatttaat gtagaaggta
     1321 ttaaattata tgtattcttt gtcggtagat taaaagtaaa aaatatacta taattagata
     1381 gcataagaga aaatgccaat acagggggag ttagataatg aaatatgaag aagcattaga
     1441 gtacatatca caaactaata aattcggtat aagattagga ttagaaaata tcggaaagtt
     1501 attagaatta ttaggaaatc cacaagaaac tttgaatata atacatgtag ctggaactaa
     1561 tggaaaaggt tctgtgtgtt cttttgtttc taatatacta agagagtgtg gatataaagt
     1621 tggtttatat acatctccat atttagaaac ttttactgag cgtataagag taaatggaca
     1681 aaacatacca caggatgatg ttgctagaat aattgagtta ataaaagaaa aaatagagat
     1741 tatggtaaaa gaaggctatg catatccaac agaatttgaa gtggttactg caatggcatt
     1801 ttattactat tcagaacaaa aggtagactt tgtggcatta gaagttggtt taggtggcag
     1861 atatgatgct acaaatataa taacaaaatc acttgtaagt gtgatagtat ctataagttt
     1921 ggaccataca ggtatacttg gagatacaat agaaaaaata gcgtacgaaa aggctggaat
     1981 aataaaggaa aatggagtag tactagtata tgaccagact gatgaagcaa aggatgttat
     2041 aaagtcagtt tgtaaagaga aaaaagctaa atatatagaa gttgattttg atgatataaa
     2101 cataaaaaaa tcagatataa attctcaaat atacgattgt actgtaatga aagaaactta
     2161 tagagacctt gaaataaaat tgataggcga acatcaaata aacaattcta tcttggcaat
     2221 tagtgtaata aaatatctaa aagacataaa taaattagca aatataaatg aagaatctat
     2281 aagaaaagga cttataaata ctaaatggcc aggaagaata gaaaagataa aggaaaatcc
     2341 aatttttata atagatggtg cacataatga agatggagca aaatctttgg caaaagcact
     2401 tgataagaat tttaaaggta gaaaattaac cttattaata ggtatgttag aagataaaga
     2461 tattgatagt gttttagaga tattgttgtc acattttaat aaggtaataa caacaacacc
     2521 aaataaccca agggccataa attcagatat attaagagaa aaagtattaa aatatgtaga
     2581 tgatgtaaca tcaaagcatg agatagagga tgcagtaaat tatacattag aaacatcaag
     2641 tgaggatgat attataataa gtgcaggttc attatatatg attggtacag tgagaacttt
     2701 agtaaagaaa ttataatttt ataaaataag tatacaaata aaaatataaa aaagagttgt
     2761 ctaaaaaatg gacaactctt tttatataaa ataagttttt aataatttta ctgatgttta
     2821 tataagtaat tatatagatt gacgtatagc tttagataat tggtctgggc aagaagtacc
     2881 ttttccacca cagtcaatac catttaattt atcagcaact tcaagagcat tttggccaat
     2941 tattaagctt ctaagtcctg ataaattacc attacatcct cctataaact cagcatcaac
     3001 aatcacatta ttttcatcaa cttcaaaaat catttctcta caacatacac cacttggatt
     3061 aaatgttact ttcattaaaa agacctccat taaatattat ttcttttttt aacattaata
     3121 ataataccaa atatatgcgt aataatgcaa ctataaagca taatacaagc taatgaaata
     3181 atatattatt gtagtatatg tattgtagag aggaggggtt atatgaaaat ctatatttct
     3241 aactacttat caaagagtat tagcatagtt gattattcta cacttgaact agaaaaagaa
     3301 atagtattag aagataatat atatccacac catttttgca tagaaaaaga aaaaaattta
     3361 atatacatac ctagttcaag taatgggata ctctatgtct tagatttaag taatgataaa
     3421 ataattgata ctgtctctat aggaggaagt cttagtcaag ttgtacttag cgataatgaa
     3481 ttgtttgtgg caaatgaaga ttctaatagt atatatgtac tagataaaaa cacattaaat
     3541 ccaataggaa ttattggagt tgataatatg ccacatggat ttgactttga tagagaaagc
     3601 aaaaagttat atgtaccgtg tataaactcg atagtatgta tagatacaat taataaaaat
     3661 atacaaaaga aaataaatat ggactttaga gcttggcata tagaacttga taaacaaaag
     3721 aaagaaatgt atatatcaac acttgatgga aagcttataa taatagatga agtaagcatg
     3781 gatataaaaa aggtattata tgaattttta ttaccagtag aaataagatt taattatagt
     3841 ggcaaaaaag tttatgttgc tgatttgggt tataataatg taagaatttt agattataca
     3901 acgagtagat acattggaaa tattgaaata aatgggattc cccaaggatt agaaatatct
     3961 aaagatgaaa agttactatt tgtatcagat acacaagaaa attcagtaaa agtttatgaa
     4021 actgcaaata acaaattaat aaaagaaatc aaggtaggaa aagagcctac aactataatt
     4081 tgtttgtagg ctttaatgta tgtctcttat aagtaaatcg ataacttcgg catacatata
     4141 agatgcatta tttttccagt tattgcaaat aagttttgct tgtttctctg atgaaacatt
     4201 tagatttaaa tctattaagt tagactgatt ttctatgact ctaaggttga caataaattc
     4261 attatcactt tgttttacaa aactagactt tacttgagta tctgctagta gattttcttt
     4321 gttagaatct atatacttgt ctattttttc agtaacacta gtaggtattc gattaaagaa
     4381 gtattctaga ctttctacgc ctctttgagt aagagcataa tattctctgt cagagtcttt
     4441 atatgtagtc aaaaacttag attccataag ctgagataaa agctgttgta atgaaaaata
     4501 attcatcatc tcagtctcta atactacttg agttatttga gaattagtta aatccatttt
     4561 aattttttct aatatatata aaattaaaag tttgtgatag gctaattctt cagacgagtt
     4621 ttcaaacata aatatcatcc tccgtcaaac tatttctata tataatatat taaactaatt
     4681 tgtacaaaat taaaagaaca atttgtattg tattattaat ctttaataat tcatataaaa
     4741 acaattttat aaataaatat agagaaacag ggctgctaat tagcagccct gttgataccc
     4801 aggtgtcaaa atttactatt tattttccag ccatttgtct ttcagccatt tcaactaatt
     4861 tcttagtcat atatccacca acatatccat tttctctagc tgttaagtta cctttgtcta
     4921 tgttttcata gttagataaa cctatttcgt tagctatttc taatttcatt tggtttaaag
     4981 cagcttttgc ttctggaact actgttctgt ttgaatttga catagtaaat ttcctcctca
     5041 aataattagt ttatgatgtc taacaacact tttatttatg tgatgttaat actaatttct
     5101 ccaaaataaa aataatatat acagaaaaat aaaggtaaaa atgtaaaaaa tataaaaaaa
     5161 ttaaataaat gagtatttta gagagtttaa ttaggtcaat ataggtttta tttttttagt
     5221 tattgtctta taaattaaat attacagtac ttttttgagc tgaaaaaaaa taaattttaa
     5281 atatagaaga aattatttca aagggggaat agtatgaaaa gagaagttaa aaggactaaa
     5341 gctttgatat atagtgtttt atttttttca ttattattag tgttaatatt tgtttttgtt
     5401 tatggaataa aatacatatg ttctaaatct gacaattcaa aaatgcctat atataaagtt
     5461 gatacaaatg agaaaaaaat agctttgagt tttgatgtag catggggaac tgataatatg
     5521 gatgatattt taaaaatttt agataaacat aatgtaaaag ctaccttctt tttagttggt
     5581 agttgggtgg atgataatga agaaattgta aaagctatag atgaaaaagg acatgaaatt
     5641 ggaaatcatt caaatactca tgccaatttg aaggaaatat caaaagaaga cataacaaaa
     5701 gagatagaaa ctacatcaga aaaaatatat aatataacag gaaaaaggac taatttattt
     5761 agacctcctt ttggggacgt aaacaataaa gctatggaca tttgtagtga tttaggttat
     5821 aaagtaatta agtgggatgt agattctata gattggaagg agcttggacc aaatcatgta
     5881 attgagaaag taataaaaga atctcaacct ggttcaatag ttttattcca tgctaatata
     5941 aatgatgtag ataactattt ggatactata ataagtcgac taaaaaaaga tggatacagt
     6001 ctagtcaaaa tatctgattt gttgtataaa gataattatg tagttgattc caatggagtg
     6061 caaaaaacta agaattaata agtaataaat gtatatttta agtaaagttg tgataaatta
     6121 tatagtatat gttagaaaag tgtcgataaa aagacggtgt ctattttttg acacttttta
     6181 tacatgtatg caatatcaat aattatagat taaattgatt aaaaaagtgt ctaataattg
     6241 actttttttt gatgggttta aaaatttaga agaattaatg aatgctgtaa gacagtattt
     6301 ccaaagggta taagtttgtt taaaagttgg catagaaatt gctttgttaa taagcgatat
     6361 gttctataga aataaacaat atgttaagac cttataatag aaaaatagca ttaacattat
     6421 ttgaacagct tataaaaaaa ttaatatact taagggggcg tactagttga acaaactata
     6481 ttctatttta ttaaaacaac acgttggtgg tccagataag ccagtagtaa gtgttggaga
     6541 tgtagtaaaa aaaggaactc taatcgcaga accaactgga ttaggggcaa atatttatgc
     6601 cagtgttagt ggaaaaataa gtgaaataaa tgaccaagcg atagtaattg aagctgatga
     6661 agtacaagaa gatacttttg aaccattaaa aggagaaggt atacttgact taattaaaga
     6721 agctggagta gtaggaatgg gtggagcagg attccctact catgtaaaat taaacataga
     6781 tttaaatggt ggaacaatat tagcaaatgc agctgaatgt gaacctttat tagctcataa
     6841 tataaaagaa atagaagaaa gaccagaaat agtttatcaa ggtataaaat atgctatgga
     6901 agttactaat gctggaaaag gtatgctagc aataaaaagt aagcatccaa aagcaataga
     6961 agctttcaaa aaagtaataa agccaggaga caacatagaa gttgcagaat tagttgatat
     7021 gtacccaatg ggagaagaga gagcaatagt aagagacgtt ctaggaaaat tacttgagcc
     7081 aactcaatta ccttcagagg ctaatgcagt agtaataaac gtagaaacac taactagaat
     7141 agtagaggct gttgagcaaa aaagaccagt tatatctaaa aatataactg tagttggtca
     7201 attaaacagt ggaaaagaat ctatagtgtt tgaagatgtg ccaattggaa caactgtcgg
     7261 agaattaatt gaaagagctg gtggaataaa aggtgaatat ggtgaaataa tcctaggagg
     7321 acctttcact ggtaaagcta ctactttaga tgctccaata actaaaacta gtggtggtat
     7381 aatagttact atgccatttg ttaatgaaaa gagaaaaatg ggtcttttag tttgtgcatg
     7441 tggacctaat gaagaaagaa tgagagatat agcaactaaa atgggagtta ctgatatagt
     7501 atcagttcaa aaatgtaaac aagctcaaga aattaaaggt gcattaaaat gtgaaaatcc
     7561 aggacactgt ccaggacaag ctcaaaaatg tattgaattt aagaaagctg gagcagaagt
     7621 tatattaata ggaaactgta ctgactgtag taacacagta atgggttctg caccaaaatt
     7681 aaaattaggt gtatatcata ttactgacca tgtaatgaga acagttaatc acccattaat
     7741 aagaagaata aaaggtgacg taagattaaa aataaaataa tagataaata gaagttagac
     7801 atctttagaa gtaaaactta aaagttactt ctaaggatgt tttttaatgt attttgaggg
     7861 caatatatat attgtaaaat aaatggaaaa aatagacaaa atatgctaga tattgtataa
     7921 tgataacaat agctattaca attaatattg gacaaaaata atgatactca agtatgtggt
     7981 ttgtattaat atgcatatta tattaagtca actatccgat agagtaaaag gtttttgtga
     8041 tatttgaaga tactctatag tatctttttt attataaaaa ctaatttttg ttttttatta
     8101 gataagtatc taggatacta atttatattt tattgagttg ttaaaaaagt gcacttaaaa
     8161 agttaaaaaa gaaaaattaa aaacctattt atagaaactg tgaagtatat cttaaacctg
     8221 ggcacttaaa agatatatgg agttagtagt gcaacctgct ataaatataa ataggagtaa
     8281 cttttaattg tcaaaaatat ataaaataaa tacataaata agtaattgat agaagataga
     8341 tataaatata tttttgaaat gctccctgca ttcataacga gtgtagagtg gcagatatct
     8401 gcccaaaact cctttaattg ctggaagttc ctaaagctaa ctaaaccaca acataatcat
     8461 gaaataagga taagtgtgat agagtgtgca tttaataagc acttgaggtt acgaaagtag
     8521 aaaaaattag ttagatagca taaggttaaa tcctaagtgc cttgaaaatg gataatcagc
     8581 aggtaagctt cgaaaagaag aaacttcaac gactagagag aaatctcgta cctacaagtg
     8641 tggggaaatg gggagtacct aatttatggt taggtaatga gatagtctgt gcttaataga
     8701 aatattaaga agttcatagg agaactggtt aggagtaacg accctaattg aacacactaa
     8761 agatgtatta ttgaataaga ttcatataat atttaataat tttaattata ttaagtgaat
     8821 acaatatatg tttttagtat caggagaatt ttgaaaacaa aaattaaaaa atcaagtata
     8881 atcagtttag taattgcttt tagtatggta tttactgcat ttacaccaat agtatcttat
     8941 gctgacgaag tgactagcaa tgatacaata cttaatggag aagaacaatc aaatggtcag
     9001 acaccagatg tagagaaacc atcagacggt caggtaccag atggggagaa accatcagac
     9061 agtcaagtac cagatgggga gaaaccatca gacggtcagg taccagatgg ggagaaacca
     9121 tcagatggtc agataccaga tggagagaaa ccatcagatg gtcagatacc agatggagag
     9181 aaaccatcag atggtcagat accagatgga gagaagccat cagatagtca gacgccagat
     9241 gtggagaaac catcagatgg tcagatgcca gatgtggaga aaccattaga tgagcaaact
     9301 ccagaagaag aaaaaccatt ggaagaaaaa atagttatag aggaaatgag tttaaaacaa
     9361 gatattgata aaattcttga tatgacttta tctcaaataa ataaaatagt atataacttt
     9421 tgggaagatg aagaagatgt aaaggcagat gaacaatcag aaattaacca agtttttact
     9481 tcaaaagact catttattag cttatggtat gacaaaaaag caaaagtaaa aaattcttgt
     9541 ttactaaaag aaatagatgg ttcagataga ccttatcatg atttaagatt tgatgatatt
     9601 acaaagactt taacttttga ctatgtaata aagggtcttg taggagcaag ctcaaaagac
     9661 gacaaatatg taatagaagg tgaagatgga gagcaaactg cattttgtta caataatcat
     9721 ttaagaccac caagtagtaa tggaaagagt ccatatttac cagcagaaga ttttaatggt
     9781 caagaaaacc aaaatgaaga agcagttaaa tctatactat atgcaggttc tgaatttgat
     9841 ggatttggat ataagcaaca atttaattta ggtggagaag aaaatgaatt gatgacttac
     9901 tcagctactc aaagtgcaat ttggattatt cttggacaaa tggatgaaca agaaagactt
     9961 aagcagtatc aaggttctat aaacctttgt gataaactta tagaaagagc aaaaactgaa
    10021 gaggaaagag cggagtatca gaagaggaaa gaagtagcga taaatacaaa agcttattta
    10081 gaagcattgt taaaagcagg tcgtgaagag ttaaagccaa atgatacagg aaaacctagt
    10141 ttgagtaatg gtttaactaa gattaacttt gaaaaaaatg aagatggtac ttatgaaaca
    10201 gaagctgtag ccttagtagg ttatagtggt gtagtaaagt taaaactacc agatggagta
    10261 actgcttatg atgtagatgg taatataata ggtacaggcg aagtagaaat ttcaacgcaa
    10321 cagaaattta aacttaagag tgttggaaaa ccagatgcca aagctaatat ttctgctgta
    10381 tcttatgatt atatttttcc aaaagctatt caatattata aggcagtgct tgatttagga
    10441 caaaaagacc attcatcttc attaccatct agcaagcaaa atttattaag ttatacaata
    10501 gagaaaaaga atggtcaaga agttaacttt aatataggtt taccaacaga tgatgatgtt
    10561 gtaaatccac cagtgccacc aatagatgat gatgttgtaa atccaccggt gccaccaaca
    10621 gatgatacaa atggacataa gccaaaacca tcaccaccaa tagatgatac agtaataaat
    10681 ccaccagtac caccaatgga tgatacaata ataaatccac cagtaccacc aacggaggat
    10741 gcagtgttaa atccaccagt gccaccaatg gaggatgcag tgctaaatcc accagtgcca
    10801 ccaacagatg atacagtgtt aaatccacca gtaccatcag taagtgatac agtggaaaaa
    10861 actccagaac tatcaagaga tgatacaata ataaaatcac caaaaacagg tgatgaaact
    10921 cagctaatgt catatgtatt tattagtgtc attgcaattt gtggattagc gtatcaatgt
    10981 aaaataaaaa gaaattaatc tagattatta ttaagtttaa aataaaaagt ctcaaattga
    11041 tttataagtc attttggggc ttttttatgt aaatataata tgcaaatata gtttgtttaa
    11101 aaatatctat cttaattata ttcttaaatt tatgattgga tacaggcatt cattaattgt
    11161 ttgatgaata gaaaaatgtt ttgaaggtga aaatagtatt gaaaaaataa tatactaagg
    11221 gtataattca tttgatttca tttgtataaa tttaattata aattttaaag tgattatata
    11281 aatttaaatg ctaattactt aataaatttt aataataatt atttaataaa taattattat
    11341 aatatgctag aataaatata tataaataag ttttgatgag gtactactat aaagggggga
    11401 ctttatgttt tcgataccag aagtaaaaaa agtagaagag gtaatggata caaaatttac
    11461 aactatagac gaagacacaa gaattgaaga tgcaataaaa gaaatgataa aaagcaacac
    11521 aaaaactcta atggtaatag attcatctga ccaattaaaa ggcattatat ccatgacgga
    11581 tatacataat ctttatgaga tgcataaaaa gtatgaaggt caaccagtaa aacttataat
    11641 gaagaaggat gtaatatatg tcaacgaagg tttaacctta gatgaatgta gagatataat
    11701 gatattaaaa aatataggga ttcttcctgt tcttagagat aataaaatta ttggagttct
    11761 aaaacaagag cacattaggg actatctata tatgcattta gaagattatg gattaacttt
    11821 gaagtatatt ataggtcaaa ttaaagaagg aatttgtgct ataaataacg aaggtgttgt
    11881 tatcttgtgg aataagttta tggaggaaag gtatgatata aagtctgaag atatagttgg
    11941 tcgaccgatg aatgaatttt tggaaaatac tatttcagaa aaagtactaa atagtaaagt
    12001 tggaatgagt gacttgtatt ttacagataa aaaagaaaat atgtatgcat tagttcatgc
    12061 aaatcctata ttttataaag aagaatttat cggtgttgta tgtacagaag ttgatgttac
    12121 agaagctaag atattagctc ttgaacttga aaaagtaaat gatacattaa aatatctaaa
    12181 gaacgaagtc aaaaatttat ctaaaggtag ttttgataag attttaggta aaagttataa
    12241 attggaaaaa tcgaaagcga ttgcaaaaca agtggctaga acaaatagta gcatatttat
    12301 ttggggcgaa agtggtacag gtaaagaagt atttgcaaga gctattcatg attatagtga
    12361 gagaaaaggt caatttatac ctgttaactg tagtgccata ccaaatgagt tatttgaaag
    12421 tgagtttttt gggtatgaat caggtgcgtt tacaggagca agtaaaaagg gtcgaatagg
    12481 tatatttgaa cttgcaaaag atggaactgt atttttagat gaaattgccg atttacctct
    12541 tagtatgcaa gcaaagttgc ttagagtatt acaggaaaaa gaaataagaa gagttggtgg
    12601 agataccaca ataaaaataa atcctagaat aatatcagct accaataaag atttgagtaa
    12661 aatggtaaag gcagaaaaat ttagagaaga tttatactat agattaaatg ttgttgaaat
    12721 aaagattcct ccacttagag agagaaaaga agacatagga ttattggttc atagcttttt
    12781 agaggagata tgtaaacaaa ataataagcc tgttcttaca attagcaaag atgtaataga
    12841 tatatttcag aattatagat ggaaaggtaa tattagagaa ttaaaaaata cgattgaaaa
    12901 tattgttgta ttgtcacaaa attctaaaat agatgtggat gatgtaccaa gttatatgat
    12961 ggattctaca aataatagta ctgaagaaga agagtatcct ttagatttaa cgaaggcaac
    13021 tcaaaaaatt gaaataaaga atataaccaa ggcacttaaa atgtctaatg gaaataaagc
    13081 taaagcagct aagatattaa atatacccag aacaactttg tattataaga tagaccaata
    13141 caaaatagat gtgtctaaaa tatgacacat gactaaattt tgacaaaatg ataaacttta
    13201 atttaaaacc tagtaaagcc aacgcttgta taagtgttgt gtatatagat gtgttaaaaa
    13261 aaatgaaaaa gtgttgatta attgacactt tttttgtttg agaaaatgtt tacaaataca
    13321 aaaaataaca tattttaaat aaatatttat ataatatttg gctaaaaata gcgatagatg
    13381 aagaatctat tatagaaaaa atctttttgt taataagttg gcataggaat tgcttataat
    13441 ataaagtgac tttaagtgag aaaaaaataa tattaatcat aacaaattat gtaggtttta
    13501 atttacttaa tttctcagtt aaggggttac ctgttgagga attgagattt aaaataataa
    13561 ataagaaaat aatgtaagga ggtattttat actatgtcaa taactttaga aacagctcaa
    13621 gcccatgcaa atgacccagc agtttgttgt tgtagatttg aagcgggaac aattatagcg
    13681 ccagaaaact tagaagatcc agcaatattt gcagacttag aggattctgg attattaaca
    13741 ataccagaaa atggattaac tataggtcaa gtactaggag ctaagttaaa agaaacttta
    13801 gatgcacttt ctccaatgac tacagataac gtagaaggat acaaagcagg agaggctaaa
    13861 gaagaagtag tagaagaaac agtagaagaa gcagctccag tatcagaagc agcagtagtt
    13921 ccagtaagca caggagttgc aggtgaaaca gttaaaatac acataggtga aggtaagaac
    13981 ataagcttag agataccttt atcagtagct ggtcaagcag gagttgctgc tccagtagca
    14041 aacgttgctg ctccagtggc aagtgcagca gcagaagtag ctccaaaagt tgaagaaaag
    14101 aaacttttaa gaagcttaac taaaaaacac tttaaaatag ataaagttga atttgctgat
    14161 gaaactaaaa tagaaggaac tactttatac atcagaaacg cagaagaaat atgtaaagaa
    14221 gctaatgaaa ctcaagagtt agttgtagat atgaagttag aaataataac tcctgataaa
    14281 tatgaaactt acagtgaagc tgtattagat atacaaccaa tcgctactaa agaagaaggc
    14341 gaattaggtt caggtataac tagagttata gatggagctg taatggtatt aactggtaca
    14401 gatgaagatg gagttcaaat aggtgaattt ggttcttcag aaggtgagtt aaatactact
    14461 ataatgtggg gtagaccagg tgctgctgac aaaggtgaaa tattcatcaa aggtcaagta
    14521 acaataaaag caggaactaa catggaaaga ccaggacctt tagctgctca ccgtgcattt
    14581 gactatgtaa ctcaagaaat aagagaagca ttaaagaaag ttgacaactc tttagtagtt
    14641 gatgaagaag taatagagca atacagaaga gaaggtaaaa agaaagttgt tgttataaaa
    14701 gaaataatgg gacaaggtgc aatgcatgat aacctaatat taccagttga gccagttggt
    14761 acattaggag ctcaaccaaa cgttgactta ggaaacatgc cagttgtatt atctccactt
    14821 gaagtattag atggtggtat ccatgcatta acttgtatag gacctgcatc aaaagaaatg
    14881 tcaagacatt actggagaga gccattagta ataagagcta tggaagacga agaaatagat
    14941 ttagtaggtg ttgtatttgt tggttctcca caagtaaatg ctgagaaatt ctatgtatct
    15001 aagagattag gtatgttagt tgaagctatg gaagttgatg gagctgtagt aactactgaa
    15061 ggtttcggaa acaaccatat agatttcgca tctcacatag agcaaatagg tatgagaggt
    15121 ataccagtag ttggtgtaag tttctcagct gttcaaggtg ctctagttgt tggtaataaa
    15181 tacatgactc acatggtaga caacaataag tctaagcaag gtatagagaa tgaaatatta
    15241 tctaacaaca ctttagctcc agaagatgct gttagaataa tggctatgct taaaaatgct
    15301 atagaaggtg tagaagttaa agctcctgaa agaaaatgga atccaaatgt taaattaaat
    15361 aacatagaag ctatagaaaa agttacagga gaaaaaatag tattagaaga gaatgagcaa
    15421 tctctaccaa tgagtaagaa gagaagagaa atatacgaaa aagacgaaaa ctaaaattta
    15481 gatactaact aagatttaga caataacata aatttagatc caagtttaaa acagtataga
    15541 gaggtagaat tataatggat aggttaaaat atatctcatc agagactttt tatgaaggta
    15601 ttatagttga catcaaaggt ggtggagtga ctatagacct aaaaggtaga cttggacaat
    15661 ttaaaatacc taatagaatg cttataactg actacgaact taagataggt caagaagttg
    15721 gattcatgct aagctatcct gaggtattaa gtccagagcc taatcaagag tatgtagaaa
    15781 atattaggag agaaaaagaa aaacaagcag aaatgcaatc aaaacaagaa gaaaaataat
    15841 aaataatcgt ttgaaaatag aagggagagg aaatatatga gccttacaac agtacaagga
    15901 cttcaatctg aaatattcgt tccaataaca cctcctccag tttggactcc tgtaactaaa
    15961 gaattaaaag atatgactat agctttagct acagcagctg gtgttcattt aaaatctgac
    16021 aagagattta atctagcagg agatactaca tttagagcta tacctaatac agctacagtt
    16081 gatgaaatga tggtatcaca tggtggatat gacaatggag atgtaaacaa agatataaac
    16141 tgtatgttcc ctatagatag attacatgaa ttagctgcag aaggatttat caaaggagta
    16201 gctcctatgc actatgcatt catgggtggt ggaggaaacc aacatgtctt cactgaagaa
    16261 actggtcctg ctatcgctgc taaacttaag gaagagggag tagacggtgt agttatgaca
    16321 gctggctgag gtacttgcca tagaactgcc gtgatcgtgc agagagcaat agaggaagct
    16381 ggaataccta caataataat agcagctctt cctccagtag ttagacaaaa cggaactcct
    16441 agagcagttg ctccattagt tccaatgggt gctaatgctg gtgaaccaca taatatagaa
    16501 atgcaaacac atatattaag agatacatta gagcaattag ttgcaatacc atctgctggt
    16561 aagatagttc cattaccata cgaatataaa gctcacgttt aaaatgtaat ttatatttga
    16621 aaatatagaa cccttctcct acacggttag gagaggggtt ttaagaacaa aggtggatat
    16681 tatggaagaa aaaataatga gaagacttgt tataaaaccg tttcatatga atgaagttaa
    16741 tttcggttca aaaacttcta taaagaaaga tgtacttaca atagatttat caagtataga
    16801 tgaaataaaa gaaagagaag agttaataac agacataaaa gtagacatta taaaacctgg
    16861 agattatgac agagaaatta atactattat ggacattata ccaatatcaa caaaagtttt
    16921 aggcagactg ggagagggta ttacacatac tttaacgggt gtatatgtaa tgttaactgg
    16981 tgcagatgaa gatggaaatc aaatgcatga atttggttct tcagaaggaa ttttgaaaga
    17041 ccaaatggta tttgggagat atggaactcc atcagttgaa gattatataa tccatgtaga
    17101 tgtaacttta aagggaggtt taccttttga aagaacactt ccacttgcag cattcagagc
    17161 atgtgatgat tttatacaag aaataagagc gtctttgaaa atggaagacg gaagaaatgc
    17221 tactcaagtt cgtgaatatt ttgacaaaat tcgaccaaat gcaaaaaagg ttgtcatagt
    17281 aaaacaaata gcaggtcaag gtgctatgta tgacaatcag ttattctcaa aggaacctag
    17341 tggatttgaa ggaggaacat caattataga tatgggaaat gtacctatga ttatatctcc
    17401 taatgaatac agagatggtg cccttagagc tatgacttaa gagaggtgga tattatggga
    17461 ataggacctt caacaaaaga aacatctctt catcacttta gagacccact tttagacata
    17521 gttgaaagtg ataaggatgt agatttactt ggagtaatag tagtaggaac tccagatgga
    17581 aatgaaaata aaacctttgt gggacaaaga acggccgctt ggctggaagc catgagagta
    17641 gatggagcta tagtttcatc agatggttgg ggaaactcac atgttgacta cgctaacaca
    17701 tttgaggaaa taggaaaaag agatatacct gtagttggag ttacatttaa tgggactcaa
    17761 gctaagtttg ttgtaagcaa tcaatatatg gataccatag ttgatatgaa caaatcaaaa
    17821 gaaggtattg agacagaagt agttggagaa aacaacacaa atgaaataga tgctaaaaaa
    17881 gctttggcat ttttaaaact taaaatgaga aaacatggat aaaaaattta agtaagggaa
    17941 tgagttttgt gggaatttct acatcaatga aaaacacatc acttcatata tttagagacc
    18001 cgttactaga tttgatagat aatgattctg acatagactt gttaggagtg gttgtagttg
    18061 ggacatcaga gcacaatgaa tggaaaacat ttttagcaac tagacttgga agatggattg
    18121 aatcattgcg acctgatgga gtgattataa ctttagatat ggcaggaaac caacatattg
    18181 attttacaaa tgctatagca gagtttgtaa aatcagatat acctacagta ggtcttacta
    18241 ttatgggagc agatggatta gtaattacca atccatattt ggataaagct accataattg
    18301 attataaaaa gacaacaggc tacatagaaa cagaagtagt tggagacaat cacatggatg
    18361 aagttgatgt taaaaaagca ttggctttcc taaaattaaa aatgcgtaaa gacgcaaaat
    18421 aaacctaagg gggaatttga tatgaaattt agcagaagta tacaagctat agactctcat
    18481 acagcaggtg aagcaactag aatagttgta ggtggaatac ctaacataaa aggaaattct
    18541 atgcctgaga aaaaagaata tttagaggaa aatctagatt atttaagaac tgctataatg
    18601 ttagagccaa gaggacataa tgatatgttt ggttctgtaa tgactcaacc ttgttgccca
    18661 gatgctgact ttggaataat cttcatggat ggtggcggat accttaacat gtgtggccat
    18721 ggtacaatag gagctatgac agcagctata gaaacaggtg tagttccagc agtagagcct
    18781 gtaactcatg tagttatgga agctccagca ggaataataa gaggagacgt tacagttgta
    18841 gatggaaaag ctaaagaagt atcattctta aacgtaccag ctttcttata taaagaaggt
    18901 gttgaagttg acttaccagg tgttggaact gttaaatttg acatatcatt tggtggaagc
    18961 ttctttgcta taatacatgc aagtcaatta ggtttaaaaa tcgaacctca aaatgctggt
    19021 aaattaactg aactagctat gaaacttaga gatataataa atgagaaaat agaaatacaa
    19081 catccaactt tagctcatat aaaaactgta gacttagttg aaatatatga tgagccaact
    19141 catccagaag ctacttacaa aaatgtagtt atatttggtc aaggtcaagt tgacagatct
    19201 ccatgtggaa ctggaacaag tgctaaatta gctactttac atgctaaagg tgaattaaaa
    19261 gtaggagaaa aattcgtata tgaaagtata ttaggaactt tattcaaagg tgaaatagtt
    19321 gaagaaacta aagttgcaga tttcaatgct gtagtaccta aaataactgg ttctgcttat
    19381 ataactggat ttaatcattt tgtaatagat gaagaagacc cacttaaaca tggatttatt
    19441 cttaaataag taataaataa attaggaaat taaaatagaa tagtagccac ttgtcggttg
    19501 ctattctata gcttttaggc tataagattc agaatatatg aaaaaataaa aaaataggag
    19561 gatggattat ggtagcaatc ttaaaggcat tatatgtagt attcgcagca atctttgcag
    19621 ttgtgtttgg taaagacgta gctaaagcaa acaaagaggg gaaactagaa gaacaaagta
    19681 ctccaaaagt tgctgtaaca ggatttataa cagacttctt tgatacatta ggaatagggt
    19741 catttgctcc aacaatagca atgtcaaagg ctttaaagtt aaatatacca gataaaaaaa
    19801 tgcctggtac attaaacgta gcacatacta ttccagttgt tacagaagca ttcatattta
    19861 catcaatcat accagttgat ggtgttactt tagtatctat ggttgtagca gcagcagttg
    19921 gttcatatat aggtgcagga ataatagcta agatggacga gagaaaaata caacttgtta
    19981 tgggtgtaac tttagcatta acagcaatat taatgttatt aggtcatcct tggattaacg
    20041 tattaccagg tggaggaaat gaattaggtc ttactggtgt taaattagta ataggtgtaa
    20101 taggtaactt tatactagga gctttaatga cagctggtat aggtttatat gctccaggta
    20161 tggcaatggt ttatttctta ggaatgtctg caaaagttgc attcccaata gttatgggtt
    20221 cttgtgcatt attaatgcca gttgcaagta tgaaattcat aaaagaagat gcatatacta
    20281 aaaaagcatc agttataata gctatatgtg gtttaatagg agttttcgta gctgcatata
    20341 tagtaaaaac tctaccaatg gatatattaa aagcattagt aatagtagtt atagcttata
    20401 cttctgctac aatgataatg gctgcaaata aaaacaaaaa gactgcttag ttaaagacta
    20461 cttagtgttt attaaatatt acagctaata ataaagatta taaactgctt taaaatattg
    20521 aattaatatt ttagggcagt tttttattta ctaaattaat ataaagcaat taacatgcca
    20581 attatgtaat atatatagtg atttagtaga tttaatgtaa aaaacgttgt atttttaaag
    20641 aataaagcat aatttaaagc taaatattta aattttataa tcaataagtt caataaatgt
    20701 tcatatatta atacagatta ataaaaatat aacctgtaat aagtctaata taacttataa
    20761 ttaagaaaaa taagtttata atgactcaat attcatctga attatttgaa taaatttaat
    20821 tcgttgaagt tgcttatata gagtgaataa atttaagtta tatatgactt attaactata
    20881 taataggatt tttataatta atataaaact gaaataggta gtttaattag tatatgtggt
    20941 acaaaaagat aataatttta taattataaa agtgaaatat taaatgaaat ttataactaa
    21001 ataaaaactt ttaaacagca atcaaagatt tgtaataaaa tacatccctt ataaatatat
    21061 ttattatata agctgatacc agaaatataa gaattaacaa ttgtggaggg ataaaatatg
    21121 atagctgtta aagatgagaa taacgtagta aacttaagag gggagttaga caataagcta
    21181 gaatttagcc atgagatatt tggagaaaaa ttttataata tgaaaataaa aataaacaga
    21241 ctaagcgatt cttttgatat acttccaatg actgtatcag aaagacttct ccaagatatt
    21301 gaccttgata aacaaaattt agtcaatgtc gtaggccaat taagatcata taacaaaaca
    21361 ttaaataata aaaatagatt agtgcttaca gtgtttgtca gagaaataaa aagcatagac
    21421 gaggaaaata aagaccctaa tagtatattt ttagatggat atgtatgtaa ggaacctgtg
    21481 tataggaaga cacctttagg aagggaaata accgatttat tagttgctat aaacagacct
    21541 tataataaat ctgattatat accatcaata gtttggggta gaaatgctaa atttgcaaag
    21601 aatctaaagg ttggtgatag aatacagctt tggggtaggg ttcaaagtag agaatatgag
    21661 aaaaaaatag atgaaaataa tgtggtcaaa aaaatggcat atgaagtatc catatcgaaa
    21721 ataaaaaaat tggatgaaaa taacaatgaa taaacatgaa aaatagactg atttttatga
    21781 ataaaatcct aataaatttg gtataatatc atattaaaat gtataaagat tgtttaaaaa
    21841 aatactaatg aaatatctct tgaatagttg ctcgccattt attataatgt aatctgtaca
    21901 taatttataa ttgaggaaat gaagaggtga agcattgtga aaagcatatt atgtcagata
    21961 aataaacagc cggttaaagc taaatataca tctgatgaat tagaatgttt tttggataca
    22021 attgagtata atgtaggtga taaaatattg cttgttggtc atataggaaa cctaggcaag
    22081 agattgagag gtcttggaac ttctgtaact atactggaga atagtaatta tgaagatgtc
    22141 tgttattctc tagtgtataa tgaaaattgc aatgtagtta aaggtaagtt agagtttcta
    22201 ccatttgatg ataatcagtt caacaagata ataatagttg accaatttaa tgttattaca
    22261 gattgtgaaa aagcttcatc tgaaatacaa agagtgttaa agggcaatgg agaggttata
    22321 ttagaggatt taaatttaaa gaatttaaaa gttaagttaa actatcttaa acataaattt
    22381 tgtggttctg ttgcaaagat tcactatcca catgaagtat ttaatatatt ttcaagatta
    22441 aactttgatg gtatgattaa agagtcaaat aaattaaaat atatttatgt gggaaaaaga
    22501 agataaatga gttaaaatat aaatatggat ataatataaa agactaggtt aagcctagtc
    22561 ttttgttata aggagatgtt tagatggaaa taaattatga gttaataata attgttatgc
    22621 tctttgtaat cctgatgtca atccaattta ctttaaataa gatatacttg attcttaaag
    22681 aaataagaca aatacttatg ttaaagaaaa ataaggaatg atgattatga taggtttaga
    22741 atatataaaa tctgatattc aaaatatagc tgaagctata gtatcagtac tcaatataga
    22801 tgtaactata gtaaataagg agttatttag gattgcaggt acaggagtat atatagacaa
    22861 aataggtgag aaagtagata aatatacggc ttttaaaaaa tcacttacag aacagattac
    22921 aatactaatt gatgacccaa agagtagtga tatatgtagg gaatgctata aaagtggggc
    22981 ttgtgtagag tttgcagagg tgtgttgtcc tattatatgt gatggcgatt ctcatggtgt
    23041 tataggcctt atagccttta caaaagaaca agcacaaatt atagaaaata ataaaagtgg
    23101 tcttataaac tttttaggca aaatggcaga cctaatatct aataaattaa aagcacaaat
    23161 taaaacttat gagcttgaat tagaaaagaa aaaattagag acactattaa acaatatgga
    23221 caaagctgtt gtgtctattg atgtggatgg aaaagttgat aaatataatt caaaatttaa
    23281 agagcttttc aatataaaag atagtataac tggcaaaaac atatttgtcg aattagattt
    23341 tataaagaaa ccttctataa ataactttaa gaaggacaaa tcctgtagtt ttttttataa
    23401 aagatatgga tatgattcga agggaatata caatatcaat aaaatagtat taaaaaatga
    23461 gttaaaggga tatgttattg attttataga taaaagagat gctataaaaa actacaataa
    23521 gatgaataaa gattatagaa taaaattgga aaacataatt ggagaaagtg tagctataag
    23581 aaattctaaa aaggaagccc taatagcttc taaatcaaca tcaacagtac ttattactgg
    23641 ggaaagtgga acgggtaagg agctatttgc aagagccata cacaaccata gcaatagagt
    23701 agataatcct tttatagctg taaactgtgc tgctataccg gataatttat tagagagtga
    23761 attatttgga tatgaagagg gagcttttac tggagctaaa aaaggtggaa agcttggaat
    23821 gtttgaagta gctcataagg gaagtatatt tttagatgaa ataggagata tgagtttgca
    23881 tttacagtca aagttattga gagtattaca agaaaaggaa cttaataaaa ttggaagtaa
    23941 atcaaatgtt tcaatagatg taagaattat tgctgctaca aataaagatt tagaaaaaat
    24001 ggttcaaaat ggcactttta gagaagattt atactataga ttaaatgtta tacctataaa
    24061 attaccaagt ttaagagaga gaaaagaaga tatcccactt ataatcaagc atatggttaa
    24121 agagtattca aaaaaattag ataaaaatgt tattgacata gatagcaggg ttgttgatgc
    24181 tatgatggaa tataagtggc cagggaatat aagagagttg cagaatatta ttgaatatag
    24241 tgtgaatatg tcttcttctt caataatcac aatgaatgta attcctcaaa aaattaagaa
    24301 tacctctgta gaagagttag aagttaaaag cgataggata attccacttg atgaactaga
    24361 gaagattgag ataataaaag ctttaaataa gtacaaagat tataaaaaag ataaagaatt
    24421 aacagctaaa gcacttggaa tatcaagagc tacattatat agaaaaattg aaaaatacaa
    24481 tataatttca tagtaatata ataaaaagct atataaaatt taaatttttc taaattcata
    24541 actttaaaga aagctttaaa cttatactat aagtgttttg cagaatcttt ttttatgaat
    24601 taaaaaatgg tttttataag ttaaaaaata atacatttga gccgtctcaa aatgatatag
    24661 aatctcattt tgagactttt ttttgtcttt ttgcgaaatt gtcatatgtt tatccatttt
    24721 aaagaatata aatactctat gtaaataaaa aaatacataa atagaagcag tcataccaat
    24781 ggttatagaa tataagacta aaaatataaa aagatataaa aaatatggca tgtattttgc
    24841 tataaatata gataagaaat tatttaatta attatttgag tactaaatct aaacttaatt
    24901 gggaggttta tatataatga gagatataag aaaagaatta gtggaaatgt taaaggcaga
    24961 agttaaacca gcagtagggt gtactgaacc agtagcctta gctctagcat gtgcaaaggc
    25021 aaaggaatta ttaggagaag aaatagttga aaatcgtatg ttagttagtc ctagtatcta
    25081 taaaaatggt atgtgcgtag gtataccagg tactgaaaga ttaggattaa aaattgcagc
    25141 agctctaggt atagtaggtg gacattctga aaatggatta agtgtgttag aaactctaac
    25201 aaaagaggaa gttaaaatag ctgaggatta tatggataat actccactat caataacacc
    25261 tgctgataca agagagaaag tatttataga agttgtgtta aaaggaaaaa atcatattgc
    25321 taaagtgaga ataagaacta aacatgataa ttttacgttc ttagaaaaag atggagaagt
    25381 attattagac aatgaaccaa aagtatcagc ttcaaatgat gtggcagaaa aagctgaaag
    25441 tttaatggat acagtaacta tacaagaatt aataaaaaat gtagaaggaa ttgattttaa
    25501 agatatagaa tttttactag atggagtaaa aatgaatgaa gagatggctg aatatggatt
    25561 aaaacaaaaa actggtattg gtgtcggata tggaattaaa aagtctatag aagaaggtct
    25621 tttaggtaat gatgttataa attatgcaat gatgttaact gctggagctt cggatgcaag
    25681 aatggcaggg gtaaaaatgc ctgttatgag ttcaaatgga agtggaaatc atggattaac
    25741 agcaattctt ccaatcgttg cttataataa aaaattccca caatctgatg aaagactagc
    25801 aaaagcttta gctatatctc atctagtaac tggttatatt aagaactata caggaagatt
    25861 atctgctgta tgtggatgtg gtgttgctgc ttctactgga gcaactgctg gtatctcttg
    25921 gcttatgaat ggtactgaaa agcaaataga aggagctata gaaaatatga tagctgactt
    25981 aagtggaatg atatgtgacg gtgcgaaagc tggttgtgca ttaaaattat cttctgcagc
    26041 atctgcagct atacaaagtg ctataatagc taagcaagat tgttttgtac caccactaaa
    26101 tggtatagtt ggttcaagtg ttgagcaaag tatacaaaac ttaggtagag taagtgacaa
    26161 aggtatgtct ataacagatg agataatctt aaatgtaatg aatgatatga ataaagttga
    26221 ctagtacttt ataatatgtt ttgtattatg agggataaca aaaatagcat aaataaattt
    26281 aattagtacc ctctaataaa atatgattat gtataaattt atgtataata gaaaaaactt
    26341 gttagtgcaa gttttttctt tttttgtcta aaatatatag tatgtaattt agtgtggata
    26401 tatgaactac ttaaaatata agatacattg ttaataattg ttgaatgaac ataaaaactc
    26461 aataatattg actaatattg aataagagta ttgaaaaagt gagcaatctc ttataaaatt
    26521 aagaaggatt attacaattg gaggtctttt tatggatata gaaacaaaaa aatgggaagt
    26581 attgtattca gaagaaaaaa ttaaagataa attaagggaa ttaggagcaa ttatagaaaa
    26641 agattataaa gataaaaatc ttatggtagt ttctctatta aaaggtagct ttatattttg
    26701 tgcagactta gttagaaata taaacttacc acttagagtt aattttatga ctacatctag
    26761 ttatggaaac aatgaagaaa gtactggaaa ggttaaagta gtttcagatg tgactactga
    26821 tatagcagga tatgatgttt tggttgtaga cgatattact gattctgcac ttactatgga
    26881 ttttgtgtta aaacatttaa aagctaaaaa tcctgctagt ttaaaatgct gtgttctttt
    26941 ggataaacca agcagaagaa aagtcgattt agtgccagat tattgtggat ttgaaataga
    27001 agataagttt gtggttggat atgggtttga ttttggtgat tattatagaa atgttcctta
    27061 tatattcaat gttactgatg aagatagata agcaattata taattttgtg gatgccttaa
    27121 tatgattttt attaatcgtg ttgaggtttt tttatttaaa aagtaattaa agtagtatta
    27181 aattaatttt atgcaattta attatctatt ttttataaca taataaaaaa attttaaata
    27241 attgatggga aatgagtttt ttaattgtat taataattgt aaaagatttt acaaaaaagt
    27301 aatgaaattc aagaatcaaa gcatatatgt tgatataagc aaatagatac attatcacat
    27361 aagaaattgt cgattcatat aattatatag ggtaatactc aatatttata gagtattact
    27421 ctaactttaa aaaaggagga ttaattatat gagtgatatt tcaggtccaa gtttatatca
    27481 agatgtaggt ccaacagggc caacaggtgc tactggtcca acaggaccga cggggcctag
    27541 aggtgcaacc ggagcgaccg gagcaaatgg aataacagga ccaacaggaa atacgggagc
    27601 aactggagcg aatggaataa cgggtccaac aggaaatatg ggagcgactg gaccaaatgg
    27661 aacaacaggt tctacaggac caacaggaaa tacaggagcg actggagcga atggaataac
    27721 aggtccgaca gggaatacag gagcaaccgg agcaaatgga ataacaggac caacaggaaa
    27781 caaaggagca accggagcaa atggaataac aggctctaca ggaccaacag gaaatacagg
    27841 agcgactgga gcaaatggaa taacaggacc aacagggaat acaggagcaa caggagcaac
    27901 aggtccaacc ggactaactg gagcaaccgg agcaaccgga gcaaatggaa taacaggtcc
    27961 aacaggaaat acaggagcaa ccggagcaaa tggagtaaca ggtgctacag gcccaacagg
    28021 aaatacagga gcaacaggtc caacaggaag tataggagcg actggagcaa caggaacaac
    28081 tggggcaaca ggcccaatag gagcaacagg tccaacagga gcagatggag aggtaggtcc
    28141 aacaggagca gtaggagcaa caggtccaga tggcttggta ggtccaacag gcccaacagg
    28201 cccaacggga gcaaccggag caaatggttt ggtaggccca acaggcccaa cgggagcaac
    28261 cggagcaaat ggtttggtag gtccaacagg agcgacagga gcaacaggag tagctggggc
    28321 aataggtcca accggagcag taggagcaac aggcccaacg ggagcagatg gagcagtagg
    28381 tccaacagga gcgacaggag caacaggtgt aaatggagca acaggcccaa cgggagcagt
    28441 aggagcaacc ggagcgaatg gagtagcagg tccaataggt ccaaccggtc caaccggagc
    28501 aaatggagta gcaggagcaa caggagcgac aggagcaaca ggtgcaaatg gagcaacagg
    28561 cccaaccgga gcagtaggag caacgggagc aaatggagta gcaggagcga taggaccaac
    28621 aggcccaacc ggagcaaatg gagcgacagg agcaacaggg gcgaccggag caaccggagc
    28681 aaatggagca acaggtccaa caggggcgac aggagcaaca ggagtgttag cagcaaacaa
    28741 tgcacaattt acagtgtcct cttcaagttt agtgaataat acattagtga catttaattc
    28801 atcatttata aatggaacta atataacttt tccaacaagt agtactataa atcttgcagt
    28861 tggagggata tacaatgtat ctttcggtat acgtgccaca ctttcacttg caggatttat
    28921 gtcaattact actaacttta atggagtagc tcaaaataac tttattgcaa aagcagtaaa
    28981 tacacttact tcatcagatg taagtgtaag tttaagcttt ttagttgatg ctagagcagc
    29041 agctgttact ttaagtttta catttggttc aggcacgaca ggtacttctg cagctggata
    29101 tgtatcagtt tatagaatac aatagtttat atgatgaaaa gactataaaa taataaacaa
    29161 tataattcca cataccaata aatagaataa tatttaatag gtttatatga tgaaaagact
    29221 ataaaataat aaacaatatg atttcatata ccaataaata ggataatatt taataggttt
    29281 atatgatgaa aagactataa aataataaac aatatgattt catataccaa taaattagga
    29341 taatatttaa taggtttata tgatgaaaag attataaaat aataaacaat atgattccat
    29401 ataccaataa ataggataat atttaatagg tttatatgat gaagagatta taaaataata
    29461 aacaatataa ttccatatac caataaataa gataatcttt aagaaaaatg attatattta
    29521 aaaggtaagc ataaaattta taaactttta gaatagaaat ctcaatcaat tagatattca
    29581 aattgatgaa tatgaatacc taaatagatt gagatttatt atgtacaaaa cttatcctag
    29641 tatatctgac attttataaa gtccagattg cttaccaatt aaaaatttag ctgcaactat
    29701 agaaccgttt gcaaatactt catcagattg agaatgatgg cttaatgtaa gaacttcatt
    29761 atcacctgca aatataacat catggtcgct gattatattg ccacctctta tagagtgtat
    29821 tccaatttca tttggttttc ttttacaatc tctaccatat ctaccatgtg tattttcact
    29881 ttcaggcaag acttctctaa ttgcattagc tatcatagta gcagttccac taggggcatc
    29941 ttcttttcta ttgtgatgtt tttctatgat ttcaatatca aaaccttcta acatctttga
    30001 agcatcctta actaatttta ttaatatatt tactccaaga gatgtatttg atgataataa
    30061 tataggaatg ttttttgatg cttcttctat tttatttaag tcattttcgt catatccagt
    30121 agtagctaat actacaggtg tattattttt tagagcatat gacaatattg gctctaaagt
    30181 ctcatgatgt gaaaagtcta ttatgacatc agttttttca gttacatcag tcattgtttt
    30241 gtaaagcttt gtatcactat gatgaccttt ttcatcagca gacctagcta caccacaaac
    30301 caactctaat tcattatctt tttttacaca ttctgctaaa actcttccca ttgttccatt
    30361 atagccacta attataactt tcaacataaa ttcctcctat gaaattaata aaaatttgtt
    30421 atatttctat aagtttattt tatcactaat ataatttata taaaataata ttagtgataa
    30481 taagcttaca atttatctta cattaaaaaa tttaagtgga tttttcaaaa tatagataaa
    30541 tttctttttc attgtttaaa tgataaaaat atatttgact tcataccaaa aagagtgccc
    30601 catgaactaa aaagttaatt ttgaaatacc atattcatat atcatatgat ttatttggaa
    30661 atcaatatta atacattaaa ataactaaat acatgtatgc ataaagatgt ataaaaaata
    30721 tataaacata tagtattaat tttaaattca acaatttaat tgttaaaagt gttattatta
    30781 aattagagat atcttaactt aatatactga gatgggagtg atagatatgt taaaagaaga
    30841 aaaaacttat caagagaaag acgcaaaagt attcaatgga gtggcagctt tgataatgat
    30901 tttattattt ttagtagttt caataggtat catggttttt gggatagtaa aacttgatag
    30961 tggatttact ggaataggtt cacttatgtt aattttggga cttgtattta tagtagtaga
    31021 ttttatccta ttttttgggc taagaatgat taatcctaaa gaagctatag ttctagtttt
    31081 gtttggtaac tattatggaa ctataaaaaa agaagggtac tattgggtga atccattttg
    31141 ttcagcaata aacccagcag tatcaagaat taatgtatcg aaatcttcat ctgatgaaaa
    31201 ggtagatata tcaactaatt caaggggcaa aaaagtatct ttaaaaacaa tgactcttaa
    31261 taatgaaaag cagaaagtca atgatttatt gggaaatcca attataatag gagtggttgt
    31321 aatttggaag gttatagatg caacaaaggc agtatttaat gtggataatt ataatacatt
    31381 cttatctatt cagtgtgatt ctactattcg caatgtttca agactttatc catatgatgt
    31441 atctgaagat ggagatgaaa aatctcttcg tggtagtagt caggaaatag cagatagatt
    31501 aaaagatgaa ttacaatcaa gggttgacat tgcaggaatt gaagtgtgtg aagtgagaat
    31561 tactcatctt tcttatgcac cagagattgc agcagcaatg ttacaacgtc aacaagcaga
    31621 ggctataata gcagcacgta aaaagattgt tgagggggct gtaagtatgg tagagatggc
    31681 attgactaat ttaagtgaaa ataatgttgt gactttggac gaagaacgta aagcagctat
    31741 ggtaagtaat ctgttagttg tgctttgtgg caataaagat gcacaaccag tagtaaacag
    31801 cagttctatt tattaaatta taaaaagttt aatagtttat tttattgata tatagaaaat
    31861 ttagtagttc attttattaa attatagaaa gattaatggt tcgctttatt gaattataaa
    31921 aagtttaata atttattcta ttgatatata gaaaatttag tagttcattt tattaaatta
    31981 tagaaagatt aatggttttc actttattaa attataaaaa gtttaatagt ttattacatt
    32041 gatatattga aaaattgaag gaaataaaaa tacttgtcag caagaaataa aaatgatata
    32101 agaatgaata agagaattgt aaaaaaataa aatgattata aataaaagat aaaaatattg
    32161 taaaaaagag ggtgcctctg gtgaattaaa ttcacacaga gacacctttt taattaattt
    32221 tttaaattag tatattattg tttaattaat agtatagtac tatttaatta gtctaaattt
    32281 ctaaggtctt ccataagctt agttttgtca gccgtttttt catctttcat ttttataact
    32341 ttagcaggag aaccagcaac aacagcacca gcttctacat cagtagttac aacagcacca
    32401 gctgcaacaa cagcaccttt accgattcta acaccttcaa gaataactgc attagctcct
    32461 attaaaacat catcttcaac tataacagga gtagcagaag gtggctctaa aacaccagca
    32521 acaacagcac cagcacctaa gtgaacattt ttaccaagag ttcctctagc tccaataaca
    32581 gcattcatat ctaccataga accttcacca ataacagctc ctatatttat aacagctccc
    32641 atcattacaa cagcattttt ttctatagta accatgtctc ttattattgc acctggctca
    32701 attcttgcat gttcacttaa agtatttttt agaggaatag cagaatttct tctatcatat
    32761 tctacatgag tatctgttat atcatttcca tgtttatcta atacttccat tatatcatca
    32821 tagtcaccta caaatatata agaaccatta tttccaaata ccttaaattt atcagttgat
    32881 tggaagtgta aagagttagt atttacatat accttaacag gtgttttctt tttaacttct
    32941 tttatatacc ttgctatttc ataagcatcg tttaaattta ccatttgtta attctccttg
    33001 tatttcatta tatttctttt attatatact tatttgtcaa ttttagtata tacttacttc
    33061 ttattattta tattttattt tagttagttt ttattgtata gacatagtat taaataaatt
    33121 tattatatat gtttgatttg tattgcatat tattatatat atattgtata tgtttaattt
    33181 atattgtgta ttattatatt tatactatta tcccaacatg ctgtccatat tataaaatcc
    33241 tggtttttgc ttaactaagt atttggcagc agctatagaa ccacttgcaa agataccacg
    33301 agattgagct tgatggctta ttgtaagaac ctcattgtct ccagcaaata gagcatcatg
    33361 ttcgccaaca atatttccac ctcttatagc atgaatacca acttcatttg gttgtctttt
    33421 tgcactacga ccatatctac cataattatt ttcaacgttt ggcaaaacct cttttatagc
    33481 gttagcaatc ataacagctg tgccacttgg ggcatctact tttctgttgt gatgtttttc
    33541 tattatttct atatcaaatc cttctagtaa tttagctgca tctttaacca attttactaa
    33601 tacatttaca ccaagagaca tattatatga ttggaataca ggaataactt tagccgcttc
    33661 acgtattttg ttcatttcgt catcattata tccagtagta gcaattacta aaggtgtttt
    33721 agtctttaaa acgtaagata agatattatc taaattagag tgatgagaaa aatctataac
    33781 tacatcagct tcctcaacta tagtactcat atcttcataa attttaaggt cgccttcata
    33841 gctatccaga cctctagctg caacacaaac caattctaat tcattatctt ctcttatagt
    33901 atcggctaaa atcttaccca tttttccatc ataaccagtt gctataactt ttaacataat
    33961 ttcctcctat gattaagggc taacttttga ccaaacttac tttttaccat gcattaatct
    34021 ttactatgca ttaactttta gtccaaagtt aactaattct ttctttaaca cttctaaatt
    34081 tgctgggtcc atttctgcta gaggtaatct taaatctcca acattgaatc ccaataaatt
    34141 cattgcagtc ttaactggta taggatttac ttctataaat aaagctgcga ttagagcatc
    34201 cataccaagt tgtaattttc tagaaccttc aatatcgcct tcaaagaatt tagctaccaa
    34261 atcgtgagtt tcttgagggc aaacattagc aagtactgat ataactcctt gacctcctaa
    34321 agataataaa ggaagtatag tatcatcatt accagagtag atagcaaagt catctggaac
    34381 taaactagct atttctgcaa cctgtcctag gtctccacta gcttctttta cagcaactat
    34441 gttatcaatt ttagcaagtt caactataag gctaggactt atatttacac aagttcttcc
    34501 agggacattg taaagtataa ttggaagttt aacactgtta gctattgttt caaaatgacg
    34561 cttaagtcca gctttattag ctttattgta ataaggtgtt attattaata gagcatctac
    34621 tcctaatttt tcagcttctt gacttaagtt aactgagtgc atagtatcat tagaaccact
    34681 tccagctata acaggaactc ttttattaac tttttcaaca acatacttaa tagtagcaag
    34741 ttgttcttca tcagtcatag tattagcttc accagtagta ccacaagata ctatagcatc
    34801 agtaccatta gctatttggt attcaactaa ttcacctaat ttgtcaaaat caactttgtt
    34861 atcctttgta aatggtgtaa ctagagcaac agcagaacct ttaaatatca tataaaatca
    34921 atcccctctt ttttattttt gtgttttata ttacagttac ttctaatgct tgtttttgag
    34981 ttactattaa tattttacaa aattatatat ttatacaagt ttgtatatta tactaaatcg
    35041 tatgataaag ccatttcagc tatttgaatt gcgttagttg cagcaccttt tcttatatta
    35101 tcagcaacaa cccaaagatt tacaccatta tcaacactaa aatctcttct tattcttcca
    35161 acaaatactt catctctatc atcaaattct acagcagttg gatattcgtt tttagcagga
    35221 ttatcaacta ctacaacacc tggagcttct tcaagtgttt ttactaaatc atctaactca
    35281 aatggattgt taaactcaac atttatagat tcactatgac cattttttac tggaactctt
    35341 acagtagttg cagttatttt taaatcgtag ttatcaagta ttttcatagt ttcatttacc
    35401 attttcattt cttctttagt gtatccattt tcagtgaatg aatctatatg aggaagacag
    35461 ttgtaagaga tttgatgagg gtagaatcca gtaggattac cgttcattcc tttctctaaa
    35521 tcttcaacac ctttaacacc agaaccagat acagcttggt aagtagagta aacaactctc
    35581 ttaattttgt atttatcatc aagagcttta aggggaacca tagcttgtat agtagagcag
    35641 ttaggattag ctattatacc cttatgattt tttatggctt ctggattaac ctcaggaact
    35701 actaaaggca catctggatt cattctccat tgactagagt tatctactac taagattcca
    35761 tttgaagcag ctattggagc atacttttca ctaatacttc caccagcaga gaataatgct
    35821 atttgtatgc ctctatcagt aaatgaagtt tcctttaatt cttctactat atattcttta
    35881 ccacaaaaca ttactttaga accagctgat ttagaagaag agaataaaaa tagattttct
    35941 attggaaaat ttctttcttc taatactttt aaaaatgttc tacctaccat tccagtagca
    36001 ccaactattg ctacatttac ttttttcata taaattcacc ccaattttaa attattaaaa
    36061 cattatttta ttttagttat acaagtaaga tatgttaata tttttatata tccaaaaact
    36121 ttaatattat attaacaact ttaattatat acaaaaaacg tacaaaggta tactttgtac
    36181 gtctaattta tcactcaaag taaaccctgt agctcatcac ctacaaaaat aagtgacagt
    36241 attacacatg ttatgtgcaa tcccagaaaa tattattgca agaaatattt tcttcggctg
    36301 taaatccttt ttccaatcat taacacctgc cagctactat tggatactct tagttacagc
    36361 tacctctacc ctaggttaat aggatattaa aatttgatta ttctaataat aatacatatt
    36421 taagaaaaaa tcaacttatt tatataaata ttgctaaaat ttaaatccaa aatttgtcaa
    36481 ttcttgtttt aacacattaa gattagtttc ttccatttca gctagaggaa gtcttaaatc
    36541 accaacatta aaacctaaaa tgttcatggc agttttaaca ggaactggat ttacttctat
    36601 aaataaggca gcaattaaag catccatatc aagttgtaat ttttttgagc cttcaatatc
    36661 accttcaaag aatttagtta ctaaatcatg tgtttcttta ggacatatgt tagcaagtac
    36721 agagataaca ccacttccac ctaatgataa tagtggtagt atagtatcat cattaccgga
    36781 gtatatagca aagtctttag gtactaattt agctatttct gcaacttgag ctaagtctcc
    36841 acttgcttcc ttcacagcaa ctatattatc tattttagca agttcggcca caacagatgg
    36901 ctttatattc actttagttc ttcctggtac gttgtataaa ataattggca acttaacgct
    36961 atttgctatt gtttcaaagt gaagtttaag acctttctca ttagtcttat tatagtaagg
    37021 agttattatt aaaagaccat ccacccctaa tttttcagct tcttgactca tatgaacaga
    37081 caacatagta ttgtttgaac cagtacctgc tataacaggt attctcttat taactttttc
    37141 aactgtatat tttattacag caaaaatttc agattcactc atagtagtcg cctcacctgt
    37201 tgttccacaa acaactagtg catctgtgcc attctcaatg tgatattcga ttaattcacc
    37261 taatttttca aagttgacat tattatcctc tgtaaatggg gtaactaaag caacagcaga
    37321 acctttaaat aacatataat caaatctcct tttttatcta aatttaattt tttaagtaca
    37381 ataataatta tagtacaaat taattaattt taataggtat agttaatatc ttaactgttt
    37441 aaataagata tttatattat attaatatta gaaaaatttt aaataaatgt tttattctca
    37501 aaatatgcat attaatttaa taaaatatac caaaatggaa ataaaaaata aattttatga
    37561 gaatttaata actaataatt aatatattta ggttataata aatatgtgcg taaaatctaa
    37621 caataagcaa taataccgta aatttaggag gaataatatg gatactttaa aggaactttt
    37681 taaaatagga agtggacctt caagttctca tactatggga ccacaaagag cagcagagag
    37741 atttaagaat gaaaacccag atgcagaaag ttttagagca atattatatg gtagtttggc
    37801 agctacaggg aaaggtcact taactgacta tataattgaa aaaactatag cacctaaaaa
    37861 agtcgaaatt gtttgggaag aagatattat aaaagatttt cacccaaatg ggatgaagtt
    37921 tgaagcttta gataaagata aaaatgtaac agctgaatgg actgtatatt ctgtaggtgg
    37981 aggaactata gcagaagaag gtcaaagaaa cagtaaaagc aatagtatat atcacttaga
    38041 tactatggat gagatagtaa aatggtgcaa agaaaataat aagactttgg tagattttgt
    38101 gttggaatgt gaaccaaaag acataaaaga ttatataaaa actataaaag atgctatgag
    38161 aaaatctatt gatgatggac taagtacaga tgaaataata ccaggcaagt tattattaaa
    38221 aagaagagca agtacatttt ataatgcata taaaaaagat aagagcttct caacacttgt
    38281 atatgcatat gcactagcag cttcagagca aaacgcttct ggtaatataa tagttacagc
    38341 accaacttgt ggttctgctg gagtaatacc aggaatattc tttgcaatgc aggatttcta
    38401 taattatgat gacgaaaaaa taattgaagc actacttgta gctggaataa taggtaatat
    38461 aataaaaact aacgcttcaa tatctggagc agaggtaggg tgtcaaggtg aagttggagc
    38521 cgcttgttct atggcagcag cagcagtagc atacttaaaa ggtggaacta tagaccatat
    38581 tgaatatgcg gcagaaatag cacttgaaca tcatttagga atgacttgtg accctgtata
    38641 tggatatgtt caaattccat gtatagaaag aaatgcaatg gcagctcaaa gagcttatga
    38701 tgcagctaat tatgcattat taactgatgg ctcacattct gtctccttag accaagttgt
    38761 tgaaacaatg aaagaaactg gtatagatat gatggataag tacaaagaaa cagctaaggg
    38821 tggacttgct aaacatttct tctcttgcta aaaataaaat tttccaataa taattcctct
    38881 gttttgattt atgaaacagg ggaattatta ttaatggtga attatttaat aatgcaaaat
    38941 atttttatat tcaatttagc tttttatttt taattagtat aacatgctat ataatatttt
    39001 aattataaag aaatatagaa atatttttta ataaattaga aattggagga gattacatga
    39061 gagaggcatc atatttacaa gaacaacttt ataaacatag gaagtcatta aatcctattg
    39121 cagagattgg gagaaaagag tataagactt caaaatatat aagagattat cttgataaat
    39181 taggaattga gtatgaagtt tatttagaaa caggtatagt aggtgtaata gaaggtaaaa
    39241 gacctaaaaa agatattgct tttagagctg acatagatgg tcttcatagt gaagaagggg
    39301 taaaacattt atgtggtcat gatggacatg ctactatctt acttggatta attgagtatt
    39361 taaatgataa taaagaagac ttaaatgata atatagtatt tatattccaa ccggcagaag
    39421 aaggtcctgg gggagcaaaa gctttaatag atgaaggagt gcttagaaaa tacaatattg
    39481 atgaaatata tgggcttcat atatatccag agttaccaga aggttatgta ggtacaagag
    39541 agggctattt tatggctcaa ataggagata ttgacataga aatagtgtct aaaagtggac
    39601 atggggctat gccacaaaat ggtattgatg gtatagtgat agcttcaaac tttgtaagct
    39661 cacttcaaac tatagtgtct agaaatataa gcccaataga caatgcagtg ttgactattg
    39721 gcagaattga agggggagct agaagaaata taatagctga aaatataaag atggaaggta
    39781 ctatgagatg tttcagccca gaagtgtatg agaaaatgaa gcttagagtt agagaacttg
    39841 ctagagggtt tgaattggct tataactgta aggttaatat aaatattata gatgattata
    39901 tcgctgttaa aaatgacaag gatttgtatc aagagtttgt agaggctatt ggaagtgata
    39961 ctgttgtaga gttagagcca cttatgatat cagaagattt ttcttattat caaaaagaag
    40021 ttccaggatt attttttatg ttgggttcaa gaaacgaaga aaaaggattt gtaaatggtc
    40081 ttcataatat aaactttaat tttgatgaaa agatatgtgt aaatgcattg aatgtttatt
    40141 taaaattatt aaaatacaaa gaagcaatag attaggaaaa taaattataa agattaaaaa
    40201 gcataaatac ctaaatttaa aaaaagtgta ttaataaata ccccttacat atttgtataa
    40261 atttatttta attgacaaaa atacaaataa gaaggggtga tttttttgaa agaaaaagta
    40321 caaagagaaa agaagataac taatggcaag aatactaaaa tattgacaaa tgatgatata
    40381 atgaaatatg agatagcctc agaactaggt cttatggata aagttggtga acgtggatgg
    40441 gcaggactta cagctaagga agcaggaaga attggaggta tgcttacatc acgcaaaaag
    40501 aggcttaaaa agattgtgga ggagcagaat aaaaaggatg agtcaatata gtgattttgc
    40561 gtttgtatat gatgaactta tgaatgaagt tgattataat ggttgggtta aatatataga
    40621 agatataata gatagtgaag gtgtaaaagt aaaaaatata ttggaattgg catgtggtac
    40681 gggtaatctt acaattccat tggctaaaaa aaattacgat atagctggta tagatatatc
    40741 tgatgagatg cttagtgtag caagagaaaa ggcagaaaaa gaaggagtag aattagtttt
    40801 acttcaacaa gatatatcag agcttgattt tgaaatatct gatttggact gtgtactttg
    40861 tgcttgtgat ggatttaatt atataactta tgatgatgat ttggaaaatg tattttcaaa
    40921 gacatatgaa ttattaaaga aagatggaat attcatattt gatataagtt ctttttataa
    40981 attagccaac atattgggaa ataacatgta tggagaaaat agagaagata tagcgtatat
    41041 gtggcaaaat tactttgatg aagaagagaa tctaattgaa atggaactta cattctttat
    41101 taaagatgaa tgtggaaagt ttgaaagatt tgaagagata caccaacaaa gagcatatac
    41161 tgaagatgag atagttgata tgcttgaaaa atctggattt aaggatataa aatattatgg
    41221 ggattttaca tttgacaaac ctagtgaaga aagtcaaaga atcttctttg tatgtaaaaa
    41281 ataagatatt cttgactata taagataatt attaaaaata accatgatat aaaaatatag
    41341 aaaatgcagt tttatagatt aaaagtaaag tgatgatact ttatgacttt tattttttaa
    41401 taattataaa gttctataga taaaaattaa aatatagtaa ctattactta gtaaaattaa
    41461 aataaaatgg gttttgccca aggttaagat agataagtat ttatagataa attaaggtag
    41521 taatataata aaaataagac aattaacggg acatggagga atattaatga gagattatgt
    41581 actaagagcg acatcaggaa atggtcaagt tagagcattt gtcgcaacta ctagaaatac
    41641 agtagaagaa gctagaagat tacatgaaac tacaaaagta gcaacagcag cacttggaag
    41701 aacattaaca gccacatcta taatgggatt aatgatgaaa aatgatagtg ataaattgac
    41761 tgtaataata aaaggtggag gtccaattgg aactattatc gccacatcag actctaaggg
    41821 aatggtaaaa ggatatgtag gaaatccaca agtagaggtt gaagactatc caaatggaaa
    41881 gttaaatgta gcagcagcag taggtacaga aggtgttgta aaagttataa aagacttagg
    41941 tcttagagaa ccatataatg ggacttatcc attggtaagt ggagaaattg cagaagactt
    42001 tacttattat tttgctgtat cagagcagac tccatcagta gtagctttag gtgttcttac
    42061 aaaagaagat gaagtagagt ttgctggagg atttatagtt caattaatgc cagatgcaga
    42121 agaagagact attgctaagt tagaggaaaa tgtagctaaa ttaccttcta taactaacat
    42181 gttaaaagaa ggaaaatcac cagaggatat attaaatatt gttttggatg gtttggaacc
    42241 taaaatactt gatacctgtg aagttgggtt tatgtgtgaa tgttcaaaag aaagagtaaa
    42301 aactgctttg gttgcaattg gtaaaaaatc attggctcaa ataatagaag aagataaaaa
    42361 agcagaagtt ggttgccagt tctgtaataa gaagtatatg tatagtgaag aagagttgct
    42421 tgaaatttta aaggaaatgt agactataaa aatagttgta ttgatataag taatgttata
    42481 gtaatatagt aaagtcgtat tgatatagta attaaagtat aatttattaa taatagacat
    42541 atttatatta aaaaataagt ttaataaatt tttaagctta ataaatttta agaattaaga
    42601 agctttctgg ctgtaatgtt tgcaatgttg cagttagaag gcttttttat tttattatag
    42661 ttcgtgtcaa agattgtatg aaacaataaa atattgtaaa ataatttgta tatttagact
    42721 tgatttacac aaaggtttat aagatatttg agttgattat acgaaattct atgaagtagt
    42781 aaccctgtga ctttaatcat gggaggttca gaagaaggag aaaattttaa atatggaaag
    42841 taaaacgaag tacataggaa taagtatatt aatattattg atgatatttt taattgcaaa
    42901 gaattttaac ggaaaacttg aaatacctat tcctgagagt aatagtagaa aatttaaatc
    42961 agcagcagtg ttttatcctc aacatcaaga tgatgaggtt ttatggggag gaagtgccat
    43021 tgtagatgct ataaaacagt gtggtgttga taatgtatat gtggtattag tatcagatgg
    43081 ttctggagtt aacgttttca aagctaacac aaaatttaga aatttaacta ggaagcaaaa
    43141 ggaagaactt agaaataacg agtttaaatc agctttgaga gagcttggag tgaaacctca
    43201 aaatgtgatt atacttgcag atatagataa aaaggaaggc atacattatg aattaatgga
    43261 aaagactata ttggattttg aacataagtt taaaggcaat gtgacccata tagcccatca
    43321 ctataagtat gatgaccata taatgcatag aaagaatggg gaagttttaa agaaacttaa
    43381 acgtgaaggt aagataaaag atgacttgta ttttgttaag ccaaaatatg taaagtatat
    43441 accaagaaat gaaagagcta tctataaagc aatggatttt gatgactaca ataaggttaa
    43501 gagtgcttgt tatgaatata aggttgtaaa ttcaaagcgt aaaatgtatg gtataggata
    43561 tatttcggca catagttatt ttgaacatct tctaaatgac cctgaactta cgtctgtatt
    43621 aagtgaagat taatttctta taagtagtaa gttatgtttg ataagttgat tggaattttc
    43681 tatagttttg aaggtattgg aaatttagtt ttatttaaag atttaaagat agaggttttt
    43741 agtgtttaaa attttaaagt taagttgagt aattgtatag aattatttgt gaaagaagaa
    43801 acagtgtaaa acatagtatc ttatttatgg ttttaaaatc ataggcaaga tacttttttt
    43861 atgtaactaa taccattttg agattattaa cttaagaatt ttatataatt taacactcat
    43921 atataatgat gatatttagg tagaatagat gcaattacgc ttaaataaaa taactgtatt
    43981 ttttataaaa atcaaaccct acactatact accagataaa atctacatgc tataatttga
    44041 cctgtgttta taaaaaaagg agtaatctaa taaaatagta tttcacttat gtataactaa
    44101 caactattat tacgattttc tctaaataat ttaaagaaaa ataatgcagg aggtaaaata
    44161 tgaacaatga atttataatt ttaaaaggtt gcaaagagaa caatttgaac aatatttcct
    44221 taaaaatacc aaaaagaaaa ataaccatat tcacaggggt gtcgggttct ggaaagtcat
    44281 ctattgtatt tgagacaatt gcaaaagaat cacaacgcca actaaatgaa aggtttagta
    44341 catttgtaag aagtttttta cctaagtatg gagaggttaa agctgattgt atagaaaatt
    44401 tgtcaacacc aattatcata gaccaaagta gacttggtgg aaattcaagg tcaaccctag
    44461 gtactattac agatgtaaat tcctttttaa gagctttata ttcaaggttt ggtagtgagt
    44521 atataggtaa tgccaatatg ttttctttta ataatattga tggtatgtgc ccacactgtc
    44581 atgggcttgg aaaaaagcta gttcctaata tgaaccaaat tcttgatatg aataaatcat
    44641 taaatgaagg tgctatattg ctttcagggt ttggagtggg ttcttggcat tggaatatat
    44701 tcgctgaatc aggatttttt gatattaata agaggatatg tgattattca gaagtagaat
    44761 tggaaaagtt tttgcatggt aaagcagaaa agattaagat agaaaatgct ggtcaaacta
    44821 acatgacata tgagggacta atggttaaat ttaatcgcct atacttaagt agagagggag
    44881 aaatatctga agctactaag aaaaaattga gtaaacttct tatagaagat agatgtccta
    44941 tatgtgatgg aagaagactt aatgaaagag tatataggtc tttaattaat ggttataata
    45001 tagcagattt aactagtatg caaattgatg aattggctga agttattaaa agtatagatg
    45061 aggcagaagc acaaccttta attaaaggaa taatagaaaa gttaaacagt atcatagata
    45121 taggtcttgg atatttaaca ctggatagag agacatcttc tctatcagga ggggaatctc
    45181 agcgtataaa gatggttaag tatttaaata gtaatcttgt agatttaatg tatatttttg
    45241 atgaaccaag tgtaggactt catccaaaag atgtgtataa attaaataat cttttaaaaa
    45301 aattgcgtga taaagggaat acaattatag ttgttgaaca tgacccagat gttattaaga
    45361 ttgcagacca tattgtagat gtaggaccaa aggcaggtaa gtatggtgga gaagttgtgt
    45421 atgaaggcag ttatgaaaat ctacttacaa gtggtacttt gacagggaat gctttaagta
    45481 aatttcttcc tattaaagaa agtgtaagag aacatagtgg atatttagaa gttaaaaatt
    45541 gtaataaaaa caatttaaaa aatgtatcga ttaagatacc taaaggtgta ttgactttag
    45601 ttactggagt agcaggagca ggtaaaagta cgttgattaa ggatgaattt ttaaagcaaa
    45661 atcctagtgc tgtacttata gaccaaagcc ctgtttcagc aaattcaagg tcgagtttgg
    45721 caacatatag tggaattatg aacaacataa gaagcatatt ttcaaaaaca aatggcgtaa
    45781 atgcttcttt attcagttca aattcagaag gagcttgtga taactgtaag ggttctggaa
    45841 tagtagaaat gaatcttgct tttatggaga gtataaagag tacctgcaat gtttgtgaag
    45901 gtaaaaaatt taaaaaagaa gttttagaat ataggtttca agggaagaat ataattgaag
    45961 ttcttgaaat gtctgtttta gacgcaattg agttttttaa tttaaaacag attaaaacga
    46021 aattacaatg tattgaaaaa atgggtattg gataccttac tttaggacaa actcttgata
    46081 ctttgtctgg aggagagtgt caaagattaa agcttgctag tgaattaaat aaggaaagtt
    46141 cagtgtatat attagatgaa ccaacaacag gtcttcatat ggctgatatt gagaatttta
    46201 taagtataat tgaagagatt gtagataatg gaaatacggt cataataatt gaacacaata
    46261 tagatgtaat taaaagagct gattggatta ttgagctggg acctgaagga ggaacaaaag
    46321 gcgggagagt aatatttgaa ggtattccaa aacaattatg taacaataaa atatcattaa
    46381 cagcaaaata tatagtataa taaataaaat ataataaaat tataatgata ttttaataaa
    46441 tataatgggt atataaaatg ataattaaac ttaacagtaa taaataatgt gagaaatatt
    46501 caaatttaat taaataaagt gtcagaaatt tgtttaaatt ttagtatttt aacggttctg
    46561 accttttttc ttatttttat ggagaatatc gaggatggag tctctaatag ttactttttt
    46621 gtgtctactt gcaagtttga ttaaaaaatg gctatacaca cttgtgactt cagtcatggg
    46681 aggttcagat tataatctta atatataatt tgtgaaataa tttgatgacg atttgctgat
    46741 gtataaacaa taaagattaa ctacattaaa atttaaatct tgttaagtaa aacttataaa
    46801 aggagagaga tggatgataa atgatattct aaccttatta tctgaaagaa gtgatttttt
    46861 tataaagcta tccatagaac atttgatgat ttctattatt tctataataa ttgcgattgt
    46921 tttgggtggt ataattggta ttattgtaag tgaatttcat aattcttcta aacctatatt
    46981 gggaactatc aattttctat acaccattcc atctatttct atgctaggat ttctgatacc
    47041 attttccgga attggaaata ctactgctgt tattgcactt accatttatg cattattgcc
    47101 aatggttaga aatacatata ctggaattac taatgtggat aaaaatattc ttgaagcagc
    47161 taggggaatg ggaagtacag attttcagat attgtataaa ataaaacttc cgttagccct
    47221 acctgttatt atgtctggta ttagaaatat ggtgattatg acaattgcat tagctggtat
    47281 cgcttcattt ataggtgctg gaggcctagg tgtagccata tatagaggaa tcacgacaaa
    47341 taacacaata atgacaatta ctggaagtat acttattgct ctattagctt taatatttga
    47401 ttttatttta gggctggtag aaaaattttt tcaacgaaaa agaaaaaaga aaaataggaa
    47461 aaaagttttt gccattctag gaagccttat tcttatagta attatcttta cgtcttattt
    47521 atttaatcct tcaaagactc aaactattca tattgctact aaacctatga ctgaacaata
    47581 tattcttggt gagatgttgg atattttaat tgaaaaaaac acaggtctaa acgtggaaat
    47641 tacacaaggt gtaggagggg gaacatctaa tatccagcca gctatggaga atggagaatt
    47701 tgacatttat ccagagtata caggtacagg ctggaatatg gtacttaaga aaaatgaatt
    47761 atatactgaa agtatgttta gtaaactaca gtcggaatac aaaactaaac ttaaaatgca
    47821 atggactggt atgtatggtt tttctaatag ctatgcatta gcagttagaa aagaagttgc
    47881 agataaatac aatttaaaaa atataacgga cttaaaagat gtatcttcta aattgacatt
    47941 tggagctgaa tatgactttt atgagagaga ggatggatat actccattgt gtaatacata
    48001 tggactgaac tttaaagata cagttgattt agatattgga ttaaaatacc aagctatcaa
    48061 tgaaggtaag attgacgtaa tgcctatatt tacaactgat ggtcagtata gtgtttcaga
    48121 tgttgtagtt ctaaaagatg ataaaaattt ctacccatct tatcaatgtg gaaatgttgt
    48181 tcgtttggaa gtattagagg aaaatccaga actatcaaag gtatttaaga tggttggaga
    48241 tattttgact gataaagaaa tggctaaaat gaattatgac gtagaaaaca acaatttaga
    48301 acctagagaa gttgctcgtg agtttctgaa taagaaaggt cttttataaa ttggaggaaa
    48361 tataatgaca cctattatac aatttaaaaa tattaaaaaa caatataatg ataaaactat
    48421 aatagataat cttaatttag atatagaaaa aggagagttt ttgactgtaa ttggttcgtc
    48481 tggttctggt aagacaacac tcttaaaaat gattaatggt ctgattttgc cagatggagg
    48541 aaatattttg ataaaccaaa cagatatcaa aaacgaggac ttaattaaat taagaagaag
    48601 aataggatat tgtgtacagg gaagtgttct ttttcctcat atgactgttg aagaaaatat
    48661 ttcatatgta ccaaatctcc taagtaaaaa gaataaatta gaagtaaaaa gtgctgtaaa
    48721 caagtggatg gaaatagtgg gattgccaaa tgatatgaaa gtgcgttacc catcagaatt
    48781 gtcaggtggt cagcaacaac gtgtagggat tgcaagagct ttagcttctt ctccagaaat
    48841 tttattaatg gatgaacctt ttggtgcagt tgatgagatt acacgaaagc aattacaaaa
    48901 agagataaaa gaaattcata aaaaaacagg agttacgatt atctttatta cgcatgatat
    48961 ttatgaagct ttgattttgg gaacaaagac tttggtatta aatcatggag ttgttcaaca
    49021 gtatgatact cctgagaata ttttaaatac tcctgctaac caatttgtag accagttatt
    49081 gaatataaga aaatctataa tagatgatga taatttaaaa gaataaattt aaatttaaaa
    49141 tcaaattgtt gtgataaaaa ctattgattt agagctaact tcaagttgta tacttgaagt
    49201 ggaaaagtta gattaaggta tagaagggca tttagcagtt ggctgtagac gaggtaactg
    49261 ctgaaggtgc tttcaataaa tggctagaac ctgtatctgt tgaagattat aataaattga
    49321 aataagaagc tcaatataca gagtagatag gcacttcaaa tagaagtgtc ttttgtgtgc
    49381 cataaaataa atcaaaatat tagcaaagaa tgtgaaaaac aaaataaaat aatatgctat
    49441 ctttaaaata ggagggatgc tatatggata acaatttgat taccattgaa aaaactttag
    49501 attatataga aaaacatctt ttagatgaga tgttagattt aaatgtaatt tctaaagaga
    49561 taggctattc aaaataccat ttacatagaa tgtttacatc agttgtcgga tttagtgtac
    49621 ataattatat acaaagacgt agacttactg aagcagcgag aatgctaatt tttacagaaa
    49681 aaccaattat tgagattgct ttaatctcgg ggtatgatac acaacgctct ttttcaagag
    49741 ggtttaaaaa aatgtttaaa cgtagtccta atttttttag aagacatcaa gattttttac
    49801 cactacaatt aaaatttgat attcataata gaaaaaaatt acgtggagat atggttttag
    49861 atgttaaaaa agttaattgt gcagatataa atattgttgg ctattctggt aaagtaagaa
    49921 aaggatttca tattattgga aaatgctgga gggatttgca taaaaataaa gagatgatag
    49981 aaaataaggt agatttaggt tttttaattg gagttagtga ttatagcaat tttaaagaga
    50041 ttgagaatac tcctacattt acatacattg caggtgctca agtagctact tttggcaaat
    50101 tacctaatgg aatggaaaaa ttcgtattac cgaaaagtaa ttatattgtt tttactttta
    50161 ttgggaaaaa tgaggatagt atgcaaaatg ttgtagaata tatctatcaa gaatggttcc
    50221 ctaattcaag ttgccagttt aatgaaaata atttatatga ctttgtaaaa tatggagaaa
    50281 aaactgatga gaatggtttg agtgaaattc agttttgggt tccaatcatt taaaagaagg
    50341 tattatgtat aaagtagatg gatttatata ggcaaagttt tacagcagta tgtatttata
    50401 aataatttat agtttgtagg aaagaaataa ttttactata agattatgat aaaatacaca
    50461 atactatgac aaaatagtgt taaataatag atttaatttt gcataggaaa agttctataa
    50521 tggtgtgtat tcataaataa tttataatct gtaggaaaga aatagtttta ctataagatt
    50581 atgataaaat acacaatact atgataaaat agtactaaat aatagattta attttgcaaa
    50641 ggataaggtg ttttaataaa aatgaatgta gaaaacgaat tacttaaaaa cctagataga
    50701 ttgcatacaa cagagttagg cgttgtaaga attaagaaaa atctttcttt ggagacaaat
    50761 gatgtagtga actggtgtaa aactaaaata gaatctccaa atgccattat taatagaaag
    50821 ggaaaaaact ggtatataag tgtatatgat tgtattataa cagtaaacgc tcacagttat
    50881 acaattatta cagctcataa agaaaagaaa tgaattgcaa aatacaaagg tcaaaagcat
    50941 tttccactgt ttgtagtacc tatgaagaag tatataaaat aatattactt ttgaataata
    51001 atttaaattt tggaggttga aaaaatgaat gatactgtaa aagaaaaatt ggcagagtca
    51061 ctaacttctg atactactga tattttacct tatttgcctt atttattaca agatttttgg
    51121 gaattaggaa gttcaccaga acaaatgtta caattattta gaaagcatat accttttaat
    51181 gaggatacaa aagttttgga tttagcttgt ggaaaaggtg ctgtatctgt gaagcttgca
    51241 aaagagttga atatacatat caaaggtatt gatttgatac ctgaatttat tgattatgct
    51301 agaagaaagg ctattgaata taaggttgat gctttgtgtg attttgaaat gaatgatgct
    51361 aatagttctg taaaaattga gcatgattat gattgtgtga tttttggagc tgtaggggat
    51421 attttaggta attataaaga aactataagt aagctattac ctacaataaa aagtaagggg
    51481 ttcattttaa ttgatgatgc atatgtagta gataaatcta caaatgaaca gcttaatttt
    51541 gagagggtgt atcccactta caatgagtgg tgtatattgt tcaaagaatt aggtctgaag
    51601 ctaattgaat gtataccatg tttagaactt gaaaatgatg ttgaagagga aatgaattgg
    51661 attataactc gtgcaaatga gctaattaaa aaatatcctt ctcaaaaaga tatgtttgaa
    51721 caatatgtta ttagccaaaa aaatgaatat actgatttac agcaggacct tgttggagca
    51781 acttggattt tacaaaaaga ataagataaa tattagacta gataatcaat gttatagtga
    51841 attatcccat gtctagtgaa tataaataac ataaaaaacc gtcaagatga atagtttatt
    51901 cgtgcttgac ggtttttagt atttgttgaa gtaaaatttt atttctttag tatatcactt
    51961 ttagtcaatc catttgattt agcttgagta ttccattgat gattccccat aagtttatat
    52021 aggaatctag ggaagttagg tgaaataaaa atagtacttt tgttggaatc atctatatgt
    52081 atattatcac taagtatatt ttttgaaagt tcttttaatg caattcctaa atctttttta
    52141 ggtcctttac ccaaaggtac ggattctagt gaaccaaaca tctccccagc tccaattcca
    52201 ataccttgaa cccatgtaaa gttgattttt ttacaccaat gctctatcat ttgaattgcc
    52261 aaatgattat gttcaccttc attgaatcca cagttaacta ttgcatacac tggaataggt
    52321 tttttatttt gtgtttttaa aaatttttca catttctcta aaaaatgaag taaatgagat
    52381 ggaataccat ctacataaag aggagatgcg attattaatc tatcacaatt aagtatggca
    52441 ttaagagcgt caggatactt agatgtgcta tctactttaa atgtaaaaac tttattatca
    52501 ttttgaataa gttgttttaa ttcagataaa aaatactgtg aattattttt atttactttt
    52561 ggactaccat ttatcattac tatattcata tggattcacc tcttatatct tgtatatttt
    52621 catagaaaca aacagagtgt tcttttatat tgaaatttat agcatttcca tttactaatt
    52681 tcgtagcagt ttctttttca gcttctgtaa tacaatctcc atagaatata gcttttaaat
    52741 ttatctgttt atcatatctg cttttatgac gcatcatatt atcttttatt acaaagtatg
    52801 gaagaatata attaatgctt ttatcaagta cgtttttgac aaaagggcta aaccctccgt
    52861 aacagcatct gcttattata ataattccat cagagtcatt tataagttta cccatgttgc
    52921 tgtaataatc ttttacaaca cattcagaag gagttttaat ccagcaacca aaacaaccaa
    52981 tacatttgtg gatttctttt gtgtttggaa gtatttttat attgtcatca agtttgggta
    53041 ataacttttc taattctttg tcagttaaat catgtattaa aagcctcata aagtccatct
    53101 ccttttatta tgtatgttta cttctaaaaa ttatatctta tagatttttc agtaaatctt
    53161 tacaccaatt aataacaaaa ttataatagt caactccata aatcattgtt gcatacatat
    53221 atgtatattg gtcaacacaa tgattttctt ctgcatcatt tttttgttta cttaatttat
    53281 ttagaagtaa ttctacttca gttattaaca tttttaagtt tgtttcaatt atttctttgg
    53341 gtagatactt gtaaaagaat atattaacaa ggtggtcttg ctttgtttta gaaaaattta
    53401 taggtttctt taaccattca agaaatactt ctttaccagt attagttatg gaatatagtt
    53461 tttttaattt gctaccatct ataacttcgt gatagtgtat atatcctttt gtttctaatc
    53521 ttttaagtgc aggatagata cttccaaagc tggcgtcaaa aaagtacgag gtactttctg
    53581 acattatttg ttttaagtcg tatccactta attctttttc cattaaaaat cctaaaataa
    53641 tgtattctaa catattacct cctggtatca attagatata tatcgattcg atatatttat
    53701 tattacagat aataaatctt acgtcaagat gctttttaaa ataagctaaa aagaattagg
    53761 agttattgat aaatatgcaa aaaaattaat ataaaaggta attaaatatc aatgaagatt
    53821 taaaaatagt taaatcaaag taagagtcta atatataaaa tttatagtaa ctttatggtt
    53881 taaatataaa cttgtgtgct attgacaaag tataaaatta gcagtaaaat aattgcatga
    53941 gcaaatagat tgttgcgaac gcaaaaaaat aaagacaata aatattaaag gagagaatat
    54001 gagagagcta ttaaaatggg tttccattat aaatagatac aatacaaatt atattgacag
    54061 gaaattggcg gatattggaa tcaataatag ccaatatttt tatgtattac acatatgtaa
    54121 taatccaggt attacacagg acactatatt tgagaaaatt cttgtgaatc ctagtaatat
    54181 aacaagagct ttggcaaatt tagaaaaaga aggctttata acaagagaac caggtgtaaa
    54241 ggataaaaga acatggcatt tatatcctac agaaaaatct ttagaatgtt atgatgaaat
    54301 actaaaaata acaaatgggt atgttgagga gttgttgagt tcatttgaga aagaagagca
    54361 agagttgttt atgtcaatgt taaagaaagt tgcatttttg gctattgata tgaatgaaga
    54421 agcaaaattg gaggcgaagg aaaatggaag aaaaatataa ggagccattg gaatatgaaa
    54481 aggtttcaaa gttattaact aagtacgcaa ttcctagtat tatagcaatg ttagtaagtg
    54541 ctttatataa cattgttgac caaatattta ttgggcaagg tgttggtgta ttgggtaatg
    54601 ctgctacaaa tgtcactttt ccactaacaa caatatgtac tgcaattgca ttattgttag
    54661 gaattggagg agcgtctaag tgttcattgg aattaggtgc taaaaattca gaaaaagcta
    54721 caaaagcagc aggaaattct atatgcttga tggctgtttt tggaataagt ttatttatag
    54781 tagtatcaat atttttaaca ccactattaa aattctttgg ctctacatca gaaatactac
    54841 cttatgcaca cacatataca aaaattacat caattggatt accatttctt ataatgtcca
    54901 ctggaatgag taagttgata cttgcagatg ggagaccgaa agcttctatg ttttgtatgt
    54961 taataggagc agttattaat acaattttga atccattatt catttttgtt tttaatatgg
    55021 gaattgctgg gtctgcttta gcaactgtta ttgggcaact tatatctttt ggaataagtg
    55081 ttcattatat aaagaatttt caacatatta aattacataa gaaaagtttt aaattagata
    55141 gtataattta taaacatata tttgcgctag gttcaagctc atgttttaat caattagcaa
    55201 tgactgtaac acagatagtt atgaataata cattggcata ttatggggct aggtcagttt
    55261 atggaagtga gattccactt gcttgtgtcg gtatcattat taaagtaaat atgattttta
    55321 tatctataat tattggtata tcacaaggta tgcaaccaat tatagggtat aattatgggg
    55381 ctgaaaagta taatcgtgta aaagaagcat ataagtttgc agtgggaagt gcaactatta
    55441 tatctgttat tgcattctta tgtttccaat tcttcccaag acaaattacg tctatatttg
    55501 gtaacggaaa tgagacttat tttatatttg cagaacatta ttttagaact ttcttgttct
    55561 taacatttat aaatggtgtt caaatagtat catcaacttt ctttacatca attggtaaat
    55621 cagtgttggg actttttact tctttgactc gtcaaatttt atttttaatt ccattgatag
    55681 taattttacc aatgtttatg ggaattgatg gagtaatgtt tgcaggacca atagcagatg
    55741 cagcagcggc aatggtatgt atatactttg cagttcatga aatgaaatca ttgactataa
    55801 agcaaaataa tttgatgagt aaccataata agattgcaga ggtataagac aatatttaag
    55861 aagtatagaa aattaattta aagaagtata ataaactaat ttaggaagta tagaaaatta
    55921 atctaaagaa gtataataaa ctaatttaga aagtatagaa aattaatcta aagaagtgta
    55981 ataaactaat ttaggaagta tagaaaatta atctaaagaa gtgtaataaa ctaatttagg
    56041 aagtatagaa aattaattta aagaagtata ataaactaat ttaggaagta tagaaagcta
    56101 atctaaagaa gtataataaa ctaatttagg aagtatagaa aattaatcta aagaagtata
    56161 ataaactaat ttaggaagta tagaaaatta atttaaagaa atacaataca ttaattttta
    56221 agtaacatta aattaatgta agtaaaataa tgttcatatg aagatttaaa ggtgcatttt
    56281 ctgaagctaa gtatatgttg tagagtgtta tgtctctcta gcctgtgaag tttaatagct
    56341 caagaaaatg cactatttat gatgattatt ttgttttatt tccaattttg gaaataacta
    56401 ttctaattaa atctaaaatt ataccataaa taagaaaaga aagtatagat gctatgtacc
    56461 aataaatcga aattgaccct gtaattgttc tacatgggat ttgcatacct gaatccataa
    56521 aaacaaaaaa actatcaact ctggaaataa tagacaaaat aggatttaaa cctattagaa
    56581 caatactttt tgagtcttga ccaatttgat gcatataaat ctcaaataat gcaattaaaa
    56641 aaaaccaaaa tgtaaaagat ttaataattt ttttcatcaa aatacctcac ataatataaa
    56701 ttttgtttgc actatttgct tactacaact atttatctcc attcagtcac atcacttaat
    56761 tgtaatctag gtcttcttga tggttcttca tcaggataac ccaaagatat tgctgccact
    56821 aattgactat ctgtatttaa ccattcacat aattcacgat atgcaaagta tacatcacaa
    56881 atccaaagac tacctagacc taattccaca gctgtaagcg acatattctg aattgcagct
    56941 ccaattgatt gcatgtttgc catttcatag aatcgttctt caggggatag cttttctaaa
    57001 ggtgatttac ctaatatatt taaaataaaa attgttactg gagcttgttt catgatttca
    57061 actgtgtaat ttgcaccagc gatatgttga cgacttcctg gaagaagccc attatcatta
    57121 atttcatttt gaataccttt gctcatggct ttaagcatag attctttttc cttttcagtg
    57181 atgacaacaa aacgccatgg ttgcctgttt ttagatgaag gtgcatttat tccagcttca
    57241 attattttct ctatagtttc atgtgaaatg ctttgatttt tatattttct gatacttcgt
    57301 ctttttgata tagaatcact tatcatttta agtaacctcc gtttattttt tggaaaaatc
    57361 tatttaattt ttattttcta ttttaattat tttagcatta atcagaaaaa aagtcattga
    57421 ttttagtata caattattaa tgattatatt aagaattgta tcaaaaagta tgtgattata
    57481 ctaagggatt atattaaata ttatatttaa aattgtatga aaggttgtat ttaatattat
    57541 attgagagag atatatatta ggatttatat atattcagat ttattattat attgagcctt
    57601 atattaaatt aaggactata atttgaaaat aagctataaa aactcaatat tgttttgttc
    57661 agagataaaa aaagaatact ttaggtgatt tttattaaaa attaagagtg ataagattat
    57721 atactttata aatgtaaata tgacgaataa aaatgataaa tataataata tatatattta
    57781 cattaggagt tttctatact ataattattt aaaactaaat ataaatgttg gaattattta
    57841 ggacttaaaa ttgtctaaaa ataaatataa gtgatgaaga ggtgatgtga tgagattaga
    57901 tatggatagt atgttatatg tactaattta tatgacatta ttggtatcta tcattggaag
    57961 tatattttat ttttgtaaag acctcttaaa tcataaaatt aagtatgttt taataagaga
    58021 catatttgta aatagaatta catattctga agaacggttg cctaaacagt atatagtttt
    58081 tcagaaatat gatatttgga ggtattgtag tttgttttaa tttgaaatga atctattata
    58141 aattctaaag tttaaaaata aaaaggagag aataaaatgg atttcatttc aagtatattg
    58201 caaggattat taagtatatt atttaatttt acaggtgatt ttggaatttc tattgtactt
    58261 ataactttaa ttgttaaatt agtacttatg ccactatcat taaaacaaag attttctgta
    58321 aaaaaacagc aagaattagc tgaaaaaatg gaacatataa aagaaaagta taagaatgat
    58381 actaaagaat tggaaaagca aatacaagta agttctgtag aaagtatgaa gagtatgctg
    58441 ggatgtctta tagttttggc tcaaatgcca gtagtatatg ctttatatca tgtatgttta
    58501 gacatgacaa aggaatttac aacaattata attccgtgga ttgctaattt aggtacattt
    58561 gataatttgt ttatattacc ttgtatatat acattaatta tgttagcttc aaatttagta
    58621 aattatatac catatttaaa aataaattct caagtaaagt ttaacaaaca aatggctgtg
    58681 gtgactacca taacaagtct tatactaact gttagaactc cagtagccat aggtctgtac
    58741 tttataacaa gtgcaattta ttcattaatt gaagatattt gttttagaat atattttaat
    58801 cgaaaaaata gaatagtgac aaaataatat aattattatt agaaatattt tagcctgcta
    58861 acatagaaaa agttagtagg ctatttttat ctatgatatc aattccatta agaagagtct
    58921 aaaaaatact atcaaaatgc tataaaaaat actatcaaaa tactataaaa aaatagttga
    58981 aaaataaata aattaatata aactaaaata aagcctacaa aaaagaggtg ataaatagaa
    59041 atggctaaaa tactaattgt agaagatgaa aaaaggatgc aaagtattat tgtagaatat
    59101 atgcaaaagg gaggatatac ttgtataact gctgatgatg gagtcgaggc acttacaata
    59161 ttaaagagca acaatataga tttaatgata ttggatatta tgatgccgta tttagatgga
    59221 ttttcagtgt gtagagtttc acgtgaaatg actaatatac ctattattat attgacagct
    59281 aaaggtgaag aggaggacaa attaaagggt tatgaatatg gcgcagatga ttatataaca
    59341 aaaccattta gcccaaaagt acttttagca aaagttaatg ctttgttacg tagatacact
    59401 actgatattc ccaaaaattc attgagttta ggaaagattt ttattatggt agcatcaaga
    59461 caagtgtatg tagaagataa attgattgat ttaacatata aagaatttga attattgcgt
    59521 ttatttatgg aaaaccctaa tcaagttttt tccagagaga aacttttaaa ttgtatatgg
    59581 ggatatgatt ttgaaggaaa cacacgaact gtagatacac atataaaaac cttacgcaaa
    59641 aagcttggta gtgaaggaca ccatatagtt acattaattc gttcaggata taagtttgag
    59701 gttaaggcat gaatagttta agaaagatta tagaaaaact gaaaaatgta gatatttcaa
    59761 attggattaa acaaaatttt ggactatatt cagttagaaa aaaagtgttt ttactttcta
    59821 aattatcagg agcgttaatt atattatttt atctggttgt tgaagaattt tcgataaact
    59881 ctaaatttga attttggatt tggtttataa tactggttat atttattatg agtattgatt
    59941 tcttattggg aaaatttatt tcagaaccaa tcacatctat aaataaatct gcaaaaagta
    60001 tgtcccaact tgatttttct aatccatgta ctgtaaatac taatgatgaa tttggagaac
    60061 tttctaggag cctgaataca atgtctacaa atctacaaca ggcattatca gacctagaaa
    60121 gtgcaaatat tcaacttgaa aaggatgtaa ataaggaaag aatgctattg gaacaaagaa
    60181 aggagttggt agatacaatt tcacatgaaa tgaagactcc acttggcatt atacgtgcgt
    60241 atacagaggg gcttatggat gaagttgatg aagaaaaaaa gaaaaattat atgaatgtta
    60301 taatagaaga aactgataga atgaacaata tgattgtatc attattagac ttatctgcat
    60361 tggaagcagg agtttctaaa cttaacccag agcgttttga ttttatagag tttgttgaaa
    60421 ctgtggcagg tcgtctttta attgatatac cagatgccaa tttttatttt acatatgatt
    60481 tgccagagta tgaagttttt gtagtggcag ataaaatgag aatggaacaa gtagtagaga
    60541 atctagttat taatgcaaag aagcatgttg tatataatgg taatttagat ttatcgatta
    60601 catgtgaaaa tggcttgctt ttatttgaaa tttataatga tggtaggttt atagagcaag
    60661 atgagatttc aaagatttgg tctaagtttt atcgtagtgt tcaatctcag cgtacaggag
    60721 gttcaggtct agggcttgca attgtttcac aaatacttac aatgcaaggg ttagaatatg
    60781 gagtgaataa tcgtgataga ggagtagagt tttattttat gattccaatt gatgaataat
    60841 ttagtattaa tttataaatc ataagtatct gatgtaaaat atttttattt gtatatgtaa
    60901 gcatttaaag agaataaaat aaaaaaactt aatgaaaaaa gcttaatgaa aaagtctaat
    60961 aaaaagttta ataaaaagct taataaaaag tcttgttttc ctgatgaaaa caagattttt
    61021 tattaagctt tttattattt cacttcgatt tcacaagaga gacactctga tttcaccaaa
    61081 tagaaataaa ataggttaaa taaattaaaa aatagaagcg taattaaata aggttacaag
    61141 ggggagtact tatgaaatgg tatacatggt tgactattat attgataata ttgctttcta
    61201 ttctgcttaa aattaaattt ataaaatggt gggatagacg acaaaaaaat gataaaggag
    61261 gttatgatag atgataaaag taagagagtt aaaattttct tatggaaaag ataaacagat
    61321 attgcatgga cttaattttg aagtaaaaga aggagaaatc tttggattcc ttggacctaa
    61381 tggttcagga aaatccacaa cacagaaaat cttaaatggc gttttaaaag gctacaatgg
    61441 gcacgtatcc atttttggga aggaagttaa agcatataca gagtctctat atcaaaagat
    61501 tggtgtttta tttgaatttc cttatttata taccaattta agtgcaattg ataatttaga
    61561 atatttttcg tctttttatc ctaaaaatca aaggagagac atatatgaac tcttagattt
    61621 gttagagttt aagaaagagt ttataaataa gcctgtatca tcctactcaa aaggtatgaa
    61681 gcaacgtatt agcatggcaa gagcattggt aagtaatcca aagttgttat ttttagatga
    61741 gcctactagt ggacttgacc catctggagc tgtactattt cgtaagatta ttgaagaaga
    61801 acgaaaaaaa ggaacaacta tctttttgac tactcataat atgctagatg cagatttaat
    61861 gtgtaacaat gtggctttta ttgcagatgg aaagattatg gtaatagata aacccaaaaa
    61921 tttaaaaatg aaaaatagca ataataaagt tgaagtggaa tttgtatata atggaaatcg
    61981 agatattgaa attgtagata tacaagagtt agaatctgga ataactttta aatatgatga
    62041 aatcttaagt gtacattcaa aagaacctac actagaagaa gtttttatta aatacacagg
    62101 aaggatgtta gtgtaatgta ttctaaattt tttaccttag taaaaaaaga tttttggatg
    62161 atgatttatg gtaaattttt tgtgctgaca cttggctctc tcatacttta ttcgtgttat
    62221 attaattttg gttatgtaaa gtttatggat gaagatagtt atcacaataa tgtatatcta
    62281 tataatccag agaatataag catgagtgca tctccattaa ttaatcaagt ttcttctata
    62341 ggtgaattaa aagcaaaact tgatgaagat acaagtgcag tttgtattga tatgagttcc
    62401 agtaagccga aagtaatttt acatgaaagt attaaaggag ttgacaatta tagagctgac
    62461 tatgcattgt cattattatc atcagaaaaa gaccataata gcaaaatatc agacaacaat
    62521 gcaataattc aaattaatga taaggataca tctgagataa aacaaagaaa agacatgact
    62581 tgtgagattt tattctttga aattgtagct attggatttt tagggattgc ctctttatta
    62641 tttaaagaaa agcagatggg agtaatgcgt attactggta ttttacctgt aaaaagaagt
    62701 ctttttatat tatcaaagat atttgctttt tttatatgtg acctatgttt tacagttctt
    62761 ttagtagtat ttaatattgg atttttagaa ggaataaaaa tacttccaca agtattagtt
    62821 caagctagta ttttatcaat tattatgtct ttgattggaa taggatgctc aatgttattg
    62881 agagatttta agcaattttc tcttatatat cttgtggttg ctgtattcat aactacacct
    62941 atatttctat ctgcaaatac atcttttgaa atagattgga ttaaatatca tcccttctat
    63001 catgtttata gtcagcttaa aaatgcgttt ttcatgaatt tttcaaaaga attagtttat
    63061 tttgtagtgt gttctttgac aataatagtt ctatttttac ttgtaaaata tatttttaat
    63121 aaagagttgg ttagggaggg ataatcttga taggattacg ttaccagtta aagagtataa
    63181 aaaaagataa aatgtgtata atttccttct ttttaccagt tgttatggcg attttaataa
    63241 attttatggg aacaattgat atatcttcat taggagagat acgttttggt atagtgaagg
    63301 atacacttcc tgtacaaaca gagcagtggt tgaagaagta tggtatggta agtgtatatg
    63361 acacaaaaat gcatttaata cgtgaaatta aggatattaa aacggacaca attggagttg
    63421 ttagagatgg taaagggata aaaactgtgc tttatggaaa tgagattaat gctataaaaa
    63481 atgttggaaa gacattgcca gagatgttta gactaaaggg tgatttaaaa gatgttgagg
    63541 ttacaatatt gcctaaatat agtattttaa aagggtttca aaatgttttt attgctatga
    63601 ttttaattac tgctatgttt atgggatgca cctttaatgc aatgaatatt atatcggaaa
    63661 aagaagatgg aatatcattt ataaatgaag ttttgccaca gagtagaagt cagtatatta
    63721 tacaaaaagt atttttgggt cttttatgtg ggtgtttatc ttcaatgata actgtattta
    63781 tatgtttgga tatttcaata ttagatatga taatgatgtt gttactcgtt gtattttcag
    63841 catttatttc atcacttata ggtttattta ttggaaagtt gtcagaaggt cttatggtag
    63901 gaattgttta tattaaaata gtaatgattt tatttatagg tactcctttg ttaatatatc
    63961 ttctaggggt taataccagt ggtataggga atttatgcta tataatgcct tcagttgcta
    64021 catttaatgg tattatggag attattaatg gtaatgtcat tattatcaaa gatattgtaa
    64081 ttttggctgt acattgtgta gtatggttta tgatatatat tattttagat aaaaaaagaa
    64141 agttatcttt tagtagataa ctcagtataa ttataattgg gacaatttaa taggtgattt
    64201 aatatacttt gtatagtgta atttatgtag tgcaatttgt atactttaat ttatgtagtg
    64261 taatagttag ttttatttta taattattca atataattta gtaagaagtt cagtacaatt
    64321 agagctactt agtggaaaac ttaataggta cttaaactat ataaatactt tattttcctc
    64381 catttgtact ataaatttaa tttatgatat aaatggaggt attattatat gatttgataa
    64441 atttcatcat tataacctac aagtaaaggt attattatat aaagttaata aagatagtat
    64501 caaaatatta tttgctataa agagagggac tcaaaataaa gataaaccta tttttcaatg
    64561 ttgaaatgat aaaatatatt tgatttcata taaaaaattt tcttcataaa ttaaaaagtc
    64621 cattttaagc cccttcattt ttaaccagat aaatcgagtt aaactattta aatatattac
    64681 tcggattcat ttgacttaga tattccttgc ttgtaaaatt gttttgaata ggggatagcc
    64741 aaagcaaaaa ataaaagtat aatccctgct atgattatta aattattaat agaaattaca
    64801 tctgccattg gtccgaaaat catcatacca agaggaataa aaccagtata tataataata
    64861 ggtaagctaa gaactctacc tagcatttgt ggtgctacat gctcttgcaa catagtcata
    64921 gctgatgctt gaatgattgg aattgaaaaa ttcgtaaaaa acataaatat aaaaaattgc
    64981 caagcttgtg ttacaagacc tagaataatt gaaaaaatag cataggataa tattgctaga
    65041 aaaaaggtct tatttctatt tttaaaacca ccaaaaactc ctataatcaa tccacctaaa
    65101 accataccta aaaatccaat catttcaata atagacaggt atatataacc cttgccaaat
    65161 gttcgttcaa taagaagtcc tataagaaat cctgatggaa cacaaagaag catgaatgct
    65221 ccataagtaa aaagcacttt tctaatgaac ttatctgaaa aacagtactt tatccctgat
    65281 accatatctg caaaaaatga gactttttca gtttgttttg gtatatcatg tttaggaatt
    65341 ttgatgaata ttaataatac aatagcaata attgcagtaa atacatcaat taaaagaact
    65401 tgatttattt tattaccaaa tccaagtatt gcagcagcta caataggaac tataaattgt
    65461 actatagact gtagactact atttatacca ttaaaacgca ttaaatgttc ttctggtaca
    65521 agttgaggaa tcattgcgtt tacagcaggt gtttgtacac cacttcctag tgaacgtata
    65581 acagatatta ctgatatggc tattaattca cttgttgtgc catttgatga catcataaat
    65641 agaattagaa ctaatgtaga tatagcaatt gttgaatctg atacaattat gagtaccttt
    65701 cgattgtagt agtctgccca tacaccagca aaaaaagaaa ttatcatttg aggtataaag
    65761 gagcatacag ttaaaactgt tacccataca cctgatgatg tctgaagtgt gacataccat
    65821 atcattgcca tttgtacaag tgatgagcca aataaggaaa tatattgact tgctaaaaaa
    65881 agaatgactt ttttcttcca tgtagaatta gtatttttat tttccatcct attcctcctt
    65941 tgatttgtgt gttgaatttt tcttgctctt aaggataaca cacaaatcaa agtctggagt
    66001 tagagtggag ggctaggaaa attgtttttt cataatttga agatgagatt tcatggtttt
    66061 tgcattatgt tcagcttctt tcaatgaagt tatcagtttg tcacacactg agataatttc
    66121 gtcatcatct tttggagtgt caaggacagt tttaatatta gtattaggat tagaagataa
    66181 agcatttaac attcgtaaaa tagctgaaag agaatagttt gcacaacgaa gtgcgcttat
    66241 aattttaagt cgttttatat cttcatcagt atatacacga taaccatttt gttttctttt
    66301 tacttttaac aaaccattca tttcccaatt tcttaaagta tctattgtaa cgtttaagtg
    66361 ttctgcagtt tcttttctag ttaaaaagag tttatttgtt tctggagtat ttccatttaa
    66421 aatctgtgca acaatagtaa gtgcttcctc ggcattagat ttttctattt ctaattgttg
    66481 caagtattga tttacaagac taatagcctt atcaaagtcc ctattcgctg atgttcttac
    66541 aatctcaagg gcatcttttc ttaatcccct ttgtaccact tcaattttca aggctgtacg
    66601 agcaaatcta aattgttcta tatgaaaatc attaaagata cgataaccat tggtattacg
    66661 cttaggttta ggtattaagt ttagttcttc atataaacgt actgtattag gatgtacacc
    66721 aattaaatct gctacctctg atgtcgtgta agtgtccatt agtattcaac tccttttaga
    66781 tatatagtat tagtcataat aacaccaaac aaaagtctgg tgttataatg gagggtttgg
    66841 ctatctaaga gtaattagtt tatgaaagag taattaattt atgaaagagt aattaatcta
    66901 ttatagaagt aagtatatat ttttcaataa actcccatct atcacgaggt ttaaacacta
    66961 ttttagatgg tatggctatt actaagtcat attgtggaat acaacaaata gcatttcctc
    67021 cagttcccat tgctgaatac cacaaaacac catctttttt acatagccac cacagataac
    67081 cgtattcatt actattcatt ttaactgatt cttcaatcca cgatttagat ataatacgtt
    67141 tattattcca aataccatca tttaaataca gaaaaccaaa tcgcaacata tctctagcac
    67201 tcaatgtaag tccccagcca cctatagaat aaccctgtct atcttttgcc caacccttaa
    67261 gattttttcc aaagaaatct tcaaaaccaa aatctttcat atcataatct ggtataactt
    67321 tcataccaat aggtttaaat aagtactcat tagcaaattc acgagcagat tttccagtag
    67381 tttttgttat aatagctgaa agtaggtgcg ttccagctga agaatatttg aaagtaccaa
    67441 tttcgccttt ttgaccaagt tgattcaagg tatattttat ccaatctttt tgtttgcaaa
    67501 gtctttctaa agactcagtc atatttttaa aagggtatgg tgcagtcatt gtaagtaggt
    67561 gacgtatagt tactgctttt ttacatattt cagaaggact acaagtatat tcaggaaaaa
    67621 aatcaacaac cttttggtca acatctttta tatatccttt atctattgca atacctatta
    67681 aggctgatat aatacttttt gtaactgatg caacatgaaa agtatcatca gcattatatc
    67741 cattatagta cttttcaaag acaatttttc cttttcttgc aataattata ccatttatat
    67801 tgctatattg tgagattatt aaaggttcaa gttgtgaaag cttttctgaa ctcataccaa
    67861 cacttgaagg gtctactttt tcaaaaatta agtctaagca attgttttta ttcattaaag
    67921 atacctccct gttatagatt ttggattttc ttttagagct tttggagaac cttctgcaat
    67981 tatataacct cctttgtcac caccttctgg accaagctca acaatccagt cacaaacatt
    68041 taatacatct atatcatgtt caacaacaat tacagaattt ccattttcaa ccaattcatc
    68101 taataattga atcaacttag aagtatcata tagacttaga ccagtagttg gctcatccaa
    68161 tacataaagg atattaccat ttcgtttttt accaatttct tttgcaagtt tgattctttg
    68221 ggattcacca ccacttaaat ttggtgtagg ttggcctaat tttatatacc ccatacctat
    68281 ttgttctaat acatttaagt gtgaaacaat atttggaata tccttgaaga aatatacaga
    68341 ttcagaaaca ctcatattta aaatatcatg tatattttta tttttatatt taatagataa
    68401 agattcatca ttaaatcttt ttccctgaca ttcactgcat atatggtcta tacttagatt
    68461 atttcccaac cagacctttt catatccact accactacat ttaggacaag cacctttgga
    68521 gttaaatgag aaatgaccag ctgtaaatcc tcgttctaac gattctggct gacctgcaaa
    68581 tagtgtacgt atcttatccc atataccaat ataagaagca ggagttgagt tcatattttt
    68641 gccaatagga gattgggata tctctgaata tccagaaata tgtttagtac caatcagtct
    68701 atctgcaata gtttcaacaa ctgcataatc gtcttcctca cctatttcac tctctgaaga
    68761 atttatttga ttattgatag tatggttatt aaattggctt ctaagaagag gaagtagggt
    68821 gtctgatata agtgaactct tgccactacc tgattttcca gatattccaa ccatagcact
    68881 caaaggtaat gatacagtta catttttaag attatttgta tttgcatttt gaatagttat
    68941 acaaggtatt ttatcagtat gtgtaatatt tttattgctt gttctattag gcattggata
    69001 ttttccagat agatactgcc cagtaagtga tttgttggat tgaagtagac cttctaaatc
    69061 tccttgatat actaattgac caccttcaac accagctttt ggaccaatat caataatatg
    69121 ttctgccatt ttaattgtgt ttttatcatg ctcaactact atgaccgtat tgcctaaatc
    69181 tttaagtttc tttattgatt ttaagatgtc tattttttct gattcatgca atccagctgt
    69241 tggttcatca agcacataaa ttaatgagtc catctctgaa tcgagatgtg aatttaaaaa
    69301 tagtctttgc atttccccac cactcaaagt tgacatttct cggtataagg atagatgacc
    69361 taatcgtgat tctattaaat gttgagtttt ggataaaata tcatttacaa gatttgtacc
    69421 aaatgtgttt aaattacctt gatttattaa gagtttaagg aaatcatcaa tttctaaaat
    69481 cgtcattttt ccaagttctc caatatgttt tccgtttaaa agtactctac gtgcttcttc
    69541 accaatttta aaaccattac aatctgaaca ggcagtcata gtataaactc catttaaatc
    69601 ttcgcccctt ttgtaacgat tgtgaaatac ctttgataaa gaggaacttt ttttaccatt
    69661 ttcataatga ccatagagta cttcatttct tatttcttca ggtagttgta agaattgtat
    69721 gtctaaataa tcgttgaatt ttttagaaaa tactctcaaa tatcctggtg taatctttgc
    69781 tctatctaag acttgtttta gggtgtcatg cttatcaagg actaattttt caatattaat
    69841 ctcaaaatat gcaccatgtc cagagcactt catacacatt ccatctgaag agttgtatga
    69901 gaaataactt ggtcttaatc gttcttcctc atatccacaa ttattgcaaa ttagattatc
    69961 gcttatagga gtatcacaca tagtacacat tatttgacct tccactgaat acaatagtgt
    70021 aagcatgttg agaatattgg ttcttgtgcc tactgttgaa cgaggattgc tctggcgaat
    70081 aatattttgt tgaacagcta tagtgggagc taaaccttga atattatcaa acttatcctc
    70141 actatcaata cctgcaagta tacctaaaga ttgcagatat tgtttacgcc cttcctcaaa
    70201 tacaatgtca aacataaggc tagacttacc tgagccactg acacctgttg caacaacaag
    70261 cttatctttg gggatagaaa catctatatt tttaagattg tgtatctttg ctccattaat
    70321 ttttatttct ttcattggtt cacctcattt tatcaatttt atcaaaccgt aaaataggga
    70381 tatattaatc cttaatacaa gaatagatta ggtgaggtta ttaaaaaggt tctataggta
    70441 aatatatatc gaccaagtgt ctattttgag ggtgattgtg tgggttgtta agatatactt
    70501 caaaagggaa ggaggcacgt agcttataat taccatttga tagccattca ttatacataa
    70561 aatcccacgc atcactatat tcagattttg aaatatcaaa atgtcccaca agatattttc
    70621 cagaaggtat tatcatattg ccaagattgt cattctcttt gacaactatg ttatctggaa
    70681 tggtcatgca aatactagtc cttaattgat gctcctgtgt aaattgtgga ttatcatgat
    70741 aaatggctaa tatttgtgtg ttttcaagtc caagtagatt ctgctcactt gcatatgtga
    70801 ataaccgttc taaaagtttt gggaaagtac tggttagatt accatatgaa ccagtatatc
    70861 tagtgtaaat agtattcata ttatcaagtt ctagaatttc aatttcacct ttaacctctc
    70921 tagtattctt acatttaggt tttgatatgc ttctattgta ctgagaaatt ttatatggtt
    70981 ctttgcaatt cttgctataa ttgtttctat attttatagg gcttatttta tagtaatttt
    71041 taaatgctct cgagaaaact gctgaatcag taaagccaaa gtagtgtgca atatcagtaa
    71101 cagtcatgtc agttctatga ataagaaaag cagttgcatt ttctagtttt agcctattta
    71161 catattgtgc caaagtttct ttttctattg ctttgaagat tctatgaaag tgaaattttg
    71221 aaaaacctgc tatattagaa agttcatcaa gagaaagagg ttcatgtaaa tgttcttcta
    71281 tatagtcttg cactttgcaa atacgattta gatattcttt tttactttta gcatttgtca
    71341 tatatagccc tccttattgt gtaaaatgtg tatcaattaa tttatagcaa tatagtaata
    71401 aaattttatg tttttgtaat ttatgataaa taagatagcg tttaattttt tataattgat
    71461 aaaagatatt tataattaat aaaagatata agatgcatta tatttatctt tgcatataag
    71521 tatagtcttc gtaataatta gtataccata gtgatttatt tttaattgtg tatttatata
    71581 aatacacaac ttatgatatg gacgaattat tatgcaaata agctgtaatt aaataaattg
    71641 caatataaac cagttgaaac ataagttagg gaaatattat caaagttatt atttagcata
    71701 agactataga tggaataaaa taagattaaa aaattacata ctaaatttaa taaaattttt
    71761 atattaaaaa taatattaag tttattgttt aaataaaaaa gttaaatcta cactattaac
    71821 ttattatact taaaacttta aaatgaaaat atcaaagaat actttttaat aaaaataatc
    71881 atttaataag ttatttaaaa atctaaaaac tttacaacaa attatctatt taaattggag
    71941 gagtgggaat atgagtaata gtttttatca attaaattca gcagtattat attttaatga
    72001 aaaaagagat gtaaatagaa taaggtttaa tcactatgta atgagaaaag aaaatataca
    72061 aagattaaaa ggaactctgc caagaggaca atttatgatg acagtaagga aagctgcatc
    72121 tgaccttgat gtatctatat ctacaataag tagacttgta aatgaattta tagatttagg
    72181 tatattgaga ttaataagta ggggagtaaa gggaaattgt tgttctgtat atagttatgt
    72241 ttgttctgaa agtagtaatg cagaaattgt aacaaagaat ggtgatattt tcaaaaatat
    72301 agagaaatac attgatgcaa ctattaacaa taaccaaaaa acaatgaaat ataaacatag
    72361 agatgagttg tttaagaaca gtaataccaa catatacagc cgtataaatc aagagagtat
    72421 agacaaagat tatgatttga taattcatac tgggtatgaa acagaaaatg agacaaagaa
    72481 aaaagaatta ttaaaaaata atttaaataa aaagaattta aataaaaata cctttgaaaa
    72541 ttcggatgaa gatttgactg aagattctac ttacaaaaat ccagaaagca tacatgaaat
    72601 tattataaga aaattaaata atgaatcagg aaaaaatttt aaagctgatt tgagtataac
    72661 taaggcactt atagataaaa gattaaaaga agggtatagt ttagaagatt tttacaaggt
    72721 tatagaggca aaagtaagaa gatggagata tacagatatg gaaatatata tagaaccaac
    72781 aattctgttt gggtatgaat ttgagtcgta tttaaatgag gagagttctt tatctgcttg
    72841 taattatggt gatatgtgtt atgaagatat gtattgagat atttattaag atattagttg
    72901 ctttttagtt gtttaaaata tgtttatgta taaatagtgt attaaaatgg agttgtctca
    72961 aaatagagag aagcctcttc ttaattgttt aaatgatgaa aatatatttg atttaataca
    73021 aaggagagtg ctttatgagt tagaagattt attttgagac actcactttt tttaatatac
    73081 tggagaaata taacccattt taatagcttt tgtaatagcc tcaactgatg atgaaacatc
    73141 tagcttgtca tatatgtgtt gtaaatgatt tgataatgtt ctttcactta tatacaattc
    73201 atcagcaatt atttttcttt ttttaccact acagataagc tgtaaaattc ttttctccat
    73261 agtagttaaa tcttcaataa ttacttcagt attttcagat ggaaaacaag ttcccccttg
    73321 atagactttt aataatgaat caattaaact atcagggcta atattcttat ttaggaatcc
    73381 atagatacct atttttttag cctcatgttt ataaactggg aggtcgtatc cagtcaagat
    73441 tattatttta atagttgaat tagtctctaa taaattataa gctactttta agccatcaca
    73501 ttcacttaag cctctaaggt ttatatccat taagacaatg tctatttttt tatcttgaat
    73561 catttctgaa agattatgga tgtcctgtgt ggaataaaac tgttcgattt ctttgtattc
    73621 ttctagtgca attgacaagc ttttagcaaa aagcatatgg tcatcaacta acaaaatatt
    73681 tataagaacc atctcctttc atagggattg taatctgtac acaaactcca tgaggtatat
    73741 tatcagaaac acttatcgtt cctcctagat tttctacttg ttctttaatt gatataatcc
    73801 ctttgtgttt tgttgtatca aaagtaattt tagttatatc taaaggcgtt ttaaaagatg
    73861 tatttgccac accattatca ctaatattta attttattat atttttttct agtgctaaag
    73921 ctatccatgc atggctacca tttgaatgtt tatacacatt tgtcaataat tctttaatca
    73981 gtcgatatat caatatatca tatggttcaa ctaagaataa agtatcagaa cacttaaatg
    74041 aaacacaaat atttttttgt ggaaaggatg aagaaacact ttcaattaaa ttctgataat
    74101 tttcttttac tgttaaattt tttaaaataa caggatgata gtcttgcatt tgcttcctta
    74161 tacatgtatt tagattgtta agtgtttcat atataatatc ttgaacatct gggcgatatg
    74221 acttactcat catgtttttt attgaaagca ggttctgtaa tatgtcatca tgtaaaaaat
    74281 tagaaaactc tgtttttagt tgttcttctt gttgtaattt ttctaatgca aaagtatact
    74341 tgctattttt aactacttta tttttttcat ctctaagatt aaactccaaa ataatgttac
    74401 agaggaaaat gagcataaat aaaacattta tagctattaa tattatagaa aaattcccat
    74461 tggcaaatag tacgaccaag ctaattacta aaatacttat aaaaagaaat atagcccttt
    74521 gttttatgtt aaaaactgtt gaaataggaa aactatcatt ttctttaagt gcaataccat
    74581 gaatactcat aaaaaatacc agtacagtta gatagattcc aaaattacca atatgatttg
    74641 atattcttag tgtaaaaaaa taataagtaa ggaatcctat aattgttata aatactgaaa
    74701 tcgatatagg ttttttttcg ctttttatga caaaaacaac ccttttcaaa tgataaaaaa
    74761 taatatagaa aaagcttatt atactaacaa caaactgtat tccgtacata caagcatacg
    74821 ttctgttaga aataaatgct cctacaattg caccaatgca ggtgataagc aataaaatgt
    74881 ctgttatctt acggaaattg tatccactac cttgaaacaa aaataaaaat ataaatttaa
    74941 tagagacata cactataact gtgcttaata ttttaaaaat aatagtgcct attggtgtgg
    75001 ttacaaatga taagagtaaa taccaactgt ctagtgctag taatccacaa aacaatgaaa
    75061 taatgttatt ttctcggaca ttacaagagg ttatatatgt gatgtctatg agtaataatg
    75121 ttgaaattat taagggaata atgctttgga tattcatata agtttcagtg cttgtagata
    75181 ttcccatgaa gagaagtgat agaatgtagt ttcctaaaaa tagtattttt aaattaaaat
    75241 ttgtcaatct tatacacctc cttatgagtt aattatatta attttatgac taaatcaaac
    75301 ctaagaatct ataattttaa attatatcaa atacttataa atgaagtata ccaaatcgtc
    75361 acacctctaa gcttgacgat ttggtaaata ttaatttttt aatacaattt tacaacagga
    75421 tttaatagta agtatataat atatcaaata cactacagaa gttaagaaaa ttgcaataat
    75481 cacaggtatg tattgtgaaa atgaatttcc aagtaaattc tgcatcaaag cagtcttata
    75541 aaccaaggta gcaaatatac agtccaatat accaagtaaa aacggaatat taaaaaatgg
    75601 caatacttgt tttttaataa tttttttaat ttgtatatta tcataaccca ttttctgtaa
    75661 aatcttataa tcagatgttg aatctgaaat tgctgatata ttgttaaagt ataaaatact
    75721 tccaacagca ataaagaata ataccacaag aaatccgatt aacagaaatg tagaactatt
    75781 aattgataac aaatcattta tcctgtgaga atatccttgt aaataagggc ttccatctaa
    75841 ataatctgaa atattactat ataaattttc attattttta attgatttac cattaatact
    75901 taaaatgctt gtcattggta atttattttg tgctatttgc tcatatatac tatcattaac
    75961 gataagtgtt ccaacgctat tggcaaaaga aatagcattg tttaatgatg tttcccttac
    76021 agctacaggt gtttctttac cattaacaag taatggataa atcgttccat tttcactata
    76081 tccatcatta tttggttgat atttcattaa aatacattca ttatccctta aaggggtaag
    76141 ttgttttagt agctttgttc gattttgtgc ctttaataaa gtataataat cagaaaaaga
    76201 tatacattca aatcctgatt ctcttgaaat aacttcttta gaagaactac tattggataa
    76261 attattctta gatgtaccaa tttcatattc aaatggaagg tcttttgatg aagattttac
    76321 cttataaata tttgtctgtg taaaaataat atcatctgta ttagacgtat attgactgac
    76381 aatttgtttt acatcttcta tttgtttatt tttttctact ctaaattcta tctctgaagg
    76441 tgcaatacgc gaaacagatg caatagggta gtataaggac agtgccataa cacttgaaac
    76501 tgtcaaagta gtagcagaga gtaatgtaag cataattaga gttttagagt ttgaacgtat
    76561 acgatagata aagtttggaa tagctattat cttcatatct gtgtagaaag tacgtttatt
    76621 ttttttacta ttttgcataa tatatggaag aaaggaattg ataaagagaa ctgtaccaat
    76681 tacaatgata atcatagtta tcaagcccat ttgataaaat ccaatactta cccatactga
    76741 tttagctcca cgaagaatat ctagtgataa acaatacccg cttaaaatca taataaaccc
    76801 cataaaggct ggaatttttc tgaactttaa ttttttttct gcactttttt catatcttat
    76861 caattttaca agtggagtct tataaaaaaa tttaccattt gatacagcta agactaaaac
    76921 aactaatgct ataaagataa ttgttttatt tattgcattt atattaaaaa atggtatctg
    76981 tgaattatca attgataaat taagtagtgc tgtaattcca aagacaatac ccttatgtgc
    77041 caatgctcct aataccaatc caataataaa agctccacta caaattaata cattttcaaa
    77101 ggtaagtagc gataatattg taaacttacg atagccaagt aaagcatata tacctaattc
    77161 ttttgtacga cgtctcaaga agaatcgatt tgagtatgcc atatagaaga tgacaaatgc
    77221 catcaaaaat atcgaaataa cattacacat agattcaact ctaccatcag ttgaaatttt
    77281 ttctagcatt atcttattaa cagaaaatga agtaaatgcg aaaaatacag taataacaaa
    77341 agagactgaa agtagatata gagaatagaa tgaaaagttt tttttaagat tctttattgc
    77401 cgtataaaaa atgttcatta aattatcctc ctatctttta gtatccaatt ttgcaatttc
    77461 ttgaataatc aactcataaa atgtatgtct attattctgt tgtttattta attctttaat
    77521 gatatgacca tctttaaaaa tcaaaattct atttgcaaaa cttgctacat aggcatcatg
    77581 tgttaccatt aaaattgttg ttttcaactc ctcatttgct tcctgtagtg agtggagtag
    77641 ttcagtagct gaattagaat ccaaagctcc tgttggttca tctgcaaaga gaatactagg
    77701 atgttttact attgctctaa ctgctgaagc tctctgtctt tgcccaccag ataattcatt
    77761 tgggtattta tttaattgag aagctatgcc aaatcgttca gctagactct ttaccatgtt
    77821 ttctatttta tctggattga gtttctgaag tgtaagaggt actgaaatat tctcgaaaat
    77881 tgtaagacta tctagtaaaa aatactcttg aaagataaag cctaaattat ccttacgaaa
    77941 atcagcagca caagtgtcat taagcgattt caaatttata ttatttatga aaatatctcc
    78001 acttgttggt ttatcaattg tagataatac attaagtaga gttgttttcc cagagccaga
    78061 agctcccatt atacctataa attcaccttc tgatacatta aaggatacct tatctaaact
    78121 cggctgttgc cctttattat aagttttagt tatgttattt acttttaata ttgtattcat
    78181 tgtatatgtc tcctttcgtc ttaatatagt caaattatat attaacctta ttgtttcttc
    78241 atgagtaaat cacgcaataa ttctacacaa attacttata tcacaatata ttgtttaaaa
    78301 tctaacttta ttaggtttgg gatgatggac aagattttaa tttaaaagag tgcatagata
    78361 tatataatgg cataatgtgg atttaaatta aaaaaaataa aataaagcca taaatattga
    78421 aaatttcaat atttatggct ttattgcttg taataattaa tagaatatat attttttatt
    78481 aatcatctat ttcaaattct aatattttac cagtaattgc attaattgtt atctcatatt
    78541 cagtttttcc ttttattatt tcaccttcat attctttgtc atcttcatca tatttaaatt
    78601 ttactatttt cccaccaggc actttatcta gcattattga tttagctttt tcagcactaa
    78661 taatagaact gttgtcatta gtattagagt tattcttatc attatcatca aagtcatcat
    78721 cagaatcatt gtccatgtca atatctacaa ttcttccatc aaatgcactt atctctaatt
    78781 catatgtttt cttatttttt attactttag cctcgtattc gttatcttca gcatcatatt
    78841 tacaatagat taaattacca ttaggaatgg catctaatgc tatagactta gctttatcca
    78901 atgatatatt ttgtgtacct aaattattat catttaagtc atcatctttt tcaatttcta
    78961 ttattttacc agagtaggca tcaatttcta tctcatatag gatattatcc tttataactt
    79021 tgcagtcata ttcattatca tcttcatcat aataacaaac taaaatattg cttcctggaa
    79081 gagcttgttt taatatttct ttagcctgta ttaaagatat ttttttagtt ttatttctta
    79141 tgttcacatt ttttagtttt aaaatatctt caaatgcttt ttgattatat cctcctccta
    79201 cttgtgttat ttcatctata tctttatttt taataaattc tttttgacta tttacaaggc
    79261 taccattaga tatcattata ggagaatttt ctttagcagc tagtactcct attgataatg
    79321 aatctactaa tgcattttct tggttaatac catctttagc tacaaataca ttatttattt
    79381 ttttatcttt ataaaattta tcaataattt ttgcattagt attgtttcta tctgaaccac
    79441 tgattctttc tctgtttgga tatttcttta ctgtattgtc tgataaaatc ttatttcctc
    79501 caactatgta agattttttt atagacctat tgtttaagaa atttatacta ctatcattgc
    79561 tgttttcatc tgatactaat attataggca tattatgtat tgctgctgga gaagctatac
    79621 taactgcatc agatagtccc tttagtccat ttacaactgc aacattttct acctttttta
    79681 tcttatctat ttctttaagt acatttgtag acatttcata tatattgttt cctactattt
    79741 tatttatttt tatgttaagt gattttattt cattttctac tttagaagaa atgctatttc
    79801 cactatctac aatgtacaca ttatctacac caagcctttt aagctcagcc ttagttgaat
    79861 tttcaatact gttgttgttt actaaaagta taggtgcatt ctttagctta gcaaatggat
    79921 ttgcacaaag cgcactttga atagaattac cattaactat aatggctgtt tttgattgaa
    79981 cccatcccaa tttacttact tctactgctg tttcatatct tgttttacct attaatcttt
    80041 cttgatttgt agtattgtct gcaaaaattg ctgaagaact agaaaaaaac atcatacctg
    80101 atattaatat agctaaattt ttcttattca tatttttacc tcacaatctt taaaaatttg
    80161 ttatttagca tacttaataa aatataatct taaaatcaaa ttgatgctga gtttgaagtt
    80221 acaaaatcaa caaataagat ttctttaata caaaattttc ctttttatat ttaacattgt
    80281 atcacaaata taaaaaggaa aaaacttttt aaaaagggta tacactattc attttttatc
    80341 ttataaataa gtctttacca ctcttttata tattttaaaa tagacacaag acctatttct
    80401 aaatctttta taaatatttt aggtgaaatt tctttttaaa catatctaaa aagtatttgt
    80461 agtaatatta atggactgaa tttcttaagg tatatatttc tttacatgtt ggagtttgtg
    80521 aagtttgaga attggagggt gaaagaaaca tgtaatggat taatattaaa gaactgtatt
    80581 tttataatat ttgtcttaaa aataaaaaaa tctattgact tgaagttaac tccaagtagt
    80641 aaagtataat tatacaagaa ttatatactt gtaagaatag ttaaagtaga gagaaaaaac
    80701 aaacaagttt taaaggggga agtaaaacaa tggaggcaaa aaaattagga tttggattaa
    80761 tgcgtttacc aataaaagat gaaaatgatg ttacaactat tgatatggaa catttaaata
    80821 aaatggtaga cacttttcta gaaaggggat ttacatattt tgatacagcc tatgtgtatc
    80881 acatgggaaa aagtgagata gcacttagag aatctctagt aaaaagacac aaaagagaga
    80941 gttttactat agctacaaaa cttccattaa tggctttaaa gaaaaaagaa gagcaagaaa
    81001 ccatttttaa tgagcaatta gaaaaatgtg gtgtagacta ttttgactac tatcttttac
    81061 acaatatagg cgtgtcacat tatgaagtag ctaaaaaatt tgatagcttt aagtttattg
    81121 aagaaaagaa aaaagaagga aaaataaaga atattggttt ttcttttcat gatagtgcag
    81181 aattattgga taaagtcttg agtgagcatc cagaagtaga cttcgtgcaa ttacagatta
    81241 attatttaga ttgggataat gaaagcatac aatctagaaa atgctacgag gtggcagaga
    81301 agcataataa gcctgtaatt gttatggagc cagtaaaagg aggtacactt gcaaagatac
    81361 cagaaaaagc agagaaatta ttgaatgact acaatccaga tatgtcaatt tcatcttggg
    81421 caatacgttt tgcagcaagt aaagataatg ttatgatggt cttaagtggg atgtcaaata
    81481 tggaacaatt attagacaat acaggatata tgcaaaattt caaaccattc gtacaagagg
    81541 aatataatat tatagatgaa gcagtagaga ttatcaacga atcaatttta gttccttgta
    81601 ctgcctgtca gtattgtgta gaaggctgtc caaaaaatat cgctattcca aactattttg
    81661 cgttgtacaa tgcagaaaaa caagctctta atactggatt ttcaacacag atggtctact
    81721 ataataatta tactaaaact tatggaaagg cctcagattg tattgaatgt aaacaatgtg
    81781 aagaaagctg tcctcaacac attaaaatta tagatgcttt aaagaatgta gcagaaacct
    81841 ttgagaaata attcaatcta tacaatatca agaggagaag atatgtatga cgatttcaga
    81901 agttagtaaa aaatacgagc tttcagcaga tactttacga tattatgaac gaattggttt
    81961 aataccacct gtaaatagaa ataaaagtgg aattaggtct tttacagaag aagattgtga
    82021 gtgggttaat ttcataaagt gtatgagagg tgcaggtctt tctattgaga cattaattga
    82081 gtatgtagct atgtttcaac aagggagcag tactatcaaa gctagaaaag aacttttaat
    82141 agagcagaga aaccaactag caaaaagaat agaagaaatg caaaaaactt tggaacgatt
    82201 aaattttaag attgatagat atgaagaagg tattattgag aaagaaaaag tattaaagag
    82261 cagtagaaat aagaaaatgg aggcagtatc ttatgagtaa aaatgtatta atagtatcag
    82321 ctagtcctag aaaaggtgga aattctgatt tattgtgtga ccagtttata caaggggtat
    82381 tagaatctaa aaatcaagtg gagaagatat ttttaaaaga taaagatatt aactattgta
    82441 ctggatgtgg tgcttgttat gaaaaagaag caaattgttc acagacagat gacatgggag
    82501 aaattcttga aaaaatgatt ggggcagatg tgattgtttt agcgactcca gtttattttt
    82561 atactatgaa tgcgcaaatg aaaactatga ttgatagaac ttgctctaga tatactgaaa
    82621 tttgtgataa agatttctat tttatcgtta cagcagcaga tgaaaatgtg gctgatatgg
    82681 aaagaacaat agaaggattt agaggattta catcatgtct aaatggttct aaggaaaaag
    82741 gtatagtata tggtgtaggt gcttggaatg taggtgatat taagggaagt aaggcaatga
    82801 aacaggcata tgaaatgggt aagttggcgt agtatatttg tataaaattg aatatattct
    82861 tatcatttca acaataaaaa gaggcttatc tgtattttga gacagcctct ttgtgctatc
    82921 atttattttt attctatatc cttattatac cctttatttt tttatgccta tttaagtatc
    82981 tgttgttgct catatatttt aataattacc cttaaaaaac tatacagatt cctgcataat
    83041 attattttct ttagtaatta atttttctag gtttttccaa tccatttctt ccatatttgc
    83101 aaaataatga ccacttccta tgcaagtcag gtaagacttt ccatctaatt caaacgaaga
    83161 acctccaata cactttgaat tacatttctt acaagtacga gttttagtta tactatcttt
    83221 aatagtttta gagcattcct ccacagcatc tttatatgta tttagatgaa aaagatttgc
    83281 tttaactctc catttttttt cattacattc aatagtaaat aagctacgtt ttggtttctt
    83341 agttgaatat actattttgt aagaacgagc acctgttttt ggttcaattt tacaatctaa
    83401 tgatttacca agttcatgta aatgacatgc aatatcataa tctttaccac ttagtacttc
    83461 taacatttct tctgttgttt ctgctgttaa ttcacttttg ctcatattaa aaaaatcccc
    83521 ctatataaat aataatttca tatgaaaata attaatataa gtatattaaa taaaactatg
    83581 aaaatcaata aaattactgc aatcttacat tattgggcat agaatgagag ctaatgattt
    83641 attagaaata agacttaata gtatgaaaat ttacttagac gtggtacaat tctataaaag
    83701 atttaaaact aggaaaggag aaagttgttg agatacggcc aatataacaa tttatttata
    83761 agttgtaaat ttattatgag attaattaga ttgttaagta atactatcaa aaggtagttt
    83821 tttggatttt cagcaacagt ggtagatatt gataattttt tggttattat tatatttagc
    83881 tgttatattt tcaataggct ctatgataac tagggtaaat aaggtatggg taaaggtttt
    83941 attatttata atagtgggat tgtcaactat agttctttca tatgtaataa cttgattatg
    84001 caaaattcta tgaagcagga accctgtgac tttagtcatg ggaggttcag aatttaaggt
    84061 taaaaaataa ctttaatctg taaattctca aaacaagaat tctcatgttg gtaaatttct
    84121 agatatgaga aaaaaattga catcataaaa aagtaatttt agagcgtttt tttacgaaaa
    84181 aattcagaag taactatttt gaatgacttc acaaaatttt atatataaat aaagtttggc
    84241 acgttaattg ctttaataaa agttaacaag acacaaataa acataatcat ctaagtattg
    84301 attatttgaa gttttagatt tgaaatttaa tctaaaggtt cgtattaata ttggtgttta
    84361 ggaaatttta ttttcctgta aatataactt aataatagga ggtgaagtca tgtcaaaagt
    84421 agtaatagct acagagaaag ctccaggagc aattggacca tattctcaag caattcaagt
    84481 tggaaacata gtttctacat caggtcaact tccaatagat atgaagactg gcgagttagt
    84541 atctgaccca aaagaagcaa caaaagcttc tttagataat gtaaaagcaa tattagaaca
    84601 agctggtaca agtatggata aaatatttaa gactacagta ttcgtaaaag atttaaagga
    84661 ttttaatgat attaatgaag tatatgctac atattttaaa gaaaatccac cagcaaggtc
    84721 atgcgtacaa gttgctcaat taccaaaaga tgcagtttta gaaattgaag caatggcagt
    84781 attataagta ttataacaat aaaaccaata acaaaactaa taaaaattaa aaactaataa
    84841 aaaaagtcta caattaaaaa agtttatatt aaaaaagtct atataaaaat ctatctaaat
    84901 atttaactat tgagcttttc tcatataatg tatattttta tgtcaaaaat atatttgtta
    84961 tatgaggaaa gctttttttt attattgtat tgtgatttat tttattgtct gcatattata
    85021 attaaggtta ctatataaaa caaacttttt ataaattaat attgtctgtt ttaacgcaaa
    85081 tatataaata agtaatgttt tatatatatt ttaaagagtg actatatgtt aaaatatagc
    85141 taaactgata atttggtaaa ttaaattcta atgggggaaa ctatgttaag taaattaaaa
    85201 gaatttcaac aagaaatgat aaaatacact gaaacagtag ctagtgtgtt agatgtagat
    85261 attgaaatag ttgacgatag attaataaga attagtggta caggtctgta taaatcaaag
    85321 ataaatgaaa gcgttgttac tgagggcttt atttatgaca atgttataca gacaggtcag
    85381 gaattagtcg tattggatat atgtgataat cagctttgta tagaatgttc ccattacatg
    85441 aaatgcctaa ataaagtaat aatagcagtt ccaataaagt ataataatcg aactatagga
    85501 gtaattggtg ctattagcac agataaaact aaaaaagtag aaataagtgc aaaaatagat
    85561 aattatttaa aatttgtcaa tcatatatgc gatttaattt ctatgaaaat agaagaacat
    85621 gaagcgtcaa aaaatagcag tagaaaaatg gatatgatga tagaaatcat tgaaaatgtt
    85681 gaaaaaggcg ttataatact agacataaat agcaaaatat cttatataaa caatatagct
    85741 ctaaaaaaat tagatataga taaaaatata atagaaaata tagtaaatat agtatctgtt
    85801 gaatcttcct caaatggaca tgaattacta gaaattgata ttgataacaa aatttataat
    85861 ataaatgcca aaataattcc ggtatatcca tatataaatc aatacgacaa aataataata
    85921 tttgacaaga catatatcaa tcataaagga catggaaaag tgaatagtgg ctggggaaat
    85981 agtgatatag agtctataat tggaaattca gaagcaatgt taaaagtaaa agagagaact
    86041 aagaaattag caaagtcaaa ttcaactgta cttataactg gggaaagtgg tacgggtaaa
    86101 gagctaattg ctagggctat acatgctgaa ggtagcagat ggaacaagcc atttattgcg
    86161 ataaactgtg ctgctattcc agaaaatctc cttgaaagtg agctatttgg ctatataaaa
    86221 ggtgcattta gtggagctag tagtggaggg aaagtaggta aatttgaact tgcaaatgaa
    86281 ggtgttatat ttcttgatga aataggagat ttgtcaatgc ctttacaagc aaagttactt
    86341 agagttttac aagagagaaa atttgcgaga attgggtcaa ataaacttat agatttagat
    86401 ataagagtga ttgctgctac aaataaaaac ttattgaaat tagtaaatga aggtaagttt
    86461 agggatgatt tatactatag attgaatgta attcctataa atttgccacc tcttagggaa
    86521 agaaaggatg atattgaggc aataatgatg aagtttgctt ctaaatattc tttagaatta
    86581 ggtattcagt taaataaaat agaagaaaat gtaatgaata tgttgattaa ctataattgg
    86641 ccgggaaata taagggaact ggaaaatgca gttgaatata tgatgaattt ggttggagat
    86701 gatggaataa tatataaaga tatgcttcca ttagatattt taaactatta taatattaat
    86761 ggaaatattt ataaaaataa ggatgtaaat ataatatttg aagatgatat agttggaggg
    86821 atagtagaga atcaagaaag gatactttca attaaagaat tagagttgac ttacataaac
    86881 aagttgttga ataagtatgg aagagataca aagacgaaga agaagatagc aaaagactta
    86941 ggcataggtt tggctacact atatagaaaa ttggaagagg aacagtagta atataatatt
    87001 aaaatgatag gtatttgtgt gtttttatag ataggtattt ttactttatg gtggaggtgt
    87061 tattatgcaa tatgcgatag agctgtatta tgataaaaaa acggaaaagc aactttttga
    87121 tttatctaaa aaaatcgctg atgaaaaaat tagtacgaag tatttagaat ggaaaacaag
    87181 acctcatctt actttggctt gtttcaatga tgtggatgag gcttgttgta tagacaagct
    87241 aaaggggttt gcacaaaacc ataaggtaat acctgcttac attggttcag taggcatgtt
    87301 taatgatact aaaacggtgt ttgtatcacc tataatgaat agcagtatgt agcagtttca
    87361 gagagaatta tatgaggtac tacaagattt tgattcaaat ggttgggaat ggtaccaccc
    87421 caatcgttgg gtaccccatt gcacaatagc acttactgga gatgatgaaa gtgaggcttt
    87481 ttttcgggca agtgatgtat tactgcgtga gttcaaaaaa ataagtggtg agtttgtctc
    87541 aataggattg gttaaaatta catttcctgt ggaagaaatt tttacagtga atatgaatag
    87601 gtaactttaa ctctgttgtg gatgttatga atattttgta tagtgcattt catcagataa
    87661 atgcgaagtt gcgaatttcg acagctcaat agtcgcaagt agggcacaat ggtacacata
    87721 ttgcactttt gcttattggg gggacgccca tgtaaacttc tgtaagaagc tatgaaaaga
    87781 tttaagccat tttggaggct ttgggtaata aagaatattt gggtaataaa gaatataaag
    87841 tatataaatt tatagagttt atgcgtaaga aggttatagc catatattta tagaaaataa
    87901 aagtagtaat atatctgaca aaacaataga catataaaaa ataagagcat aataaaggaa
    87961 gaattaagat aaataaacga tttctcgaat tgataattct cgtattgata aaaatttccc
    88021 aatatgagaa ttttttcttt tataaatctt atttttcaca ctcaaaattt ataaacttta
    88081 aagaaatttt ataaaagtat gtaattccaa cataaaaaaa ttgtttttag aataaataat
    88141 attggcacgg taattgcttt gctataaggc acaaagataa aaaattaaaa tgacaccgaa
    88201 aaatttgaaa ggggaatata aaataaatga gagaaataaa atggaaatta aataacttac
    88261 ctaaatcaga ggaaaaagaa aaaggaattg aatttttaaa agatgaagag attgcaaagg
    88321 ctaaagcttt tcatgaaagc tttccacaat atgaaaaaac tcctttagtt aaattagata
    88381 acttagcaaa atcactaggc gtaagcggaa tatatgttaa agacgaatct tatagatttg
    88441 gtttaaacgc atttaaagtt ttaggtggtt cttactctat gggtagatac ttagctcaaa
    88501 gattagatac agatatatct gagttagggt atgataaatt aacttcaaaa gaaataaaag
    88561 aaaaattagg agaaataact ttctttacag ctacagatgg aaatcatggt agaggagttg
    88621 cttggacagc taataaatta ggtcaaaaat ctgttgtatt aatgccaaaa ggttcttctg
    88681 aatttagatt aaataaaatc aaaggagaag gtgcagatgc tagtataaca gacttaaact
    88741 atgatgatgc agtaagatta gctaatgatt atgcagaagc tgatgaccat ggagtaatgg
    88801 ttcaagatac agcgtgggac ggatatgaag aaataccagc atggataatg caaggatatg
    88861 gaactatggc taaagaagct atagaacaat taaaagaata tggagtagat agaccaacac
    88921 acgtatttgt tcaagcagga gttggttcac ttgctggtgc agttcaaggg tatgttgctt
    88981 caatatatga tgaatgccca ataacagtag tagtagaggc tgatgaggct gattgttact
    89041 ataaatcagc agaagctgga gatggaaaac caagatttgt tggaggagat atgccaacta
    89101 taatggcagg gcttgcttgt ggagaaccaa acactatagg ttttgaagtg ttaaaaaatt
    89161 attcatcagc attcgtttca gcaccagact gggtatctgc taaaggtatg agaatattag
    89221 gaaaccctct aagaggagat gagaaagtaa tctctggaga atctggagca gttacaactg
    89281 gagcattagt ttcaatcctt gaaagtgaag atttaaaaga cttaagagaa gctttgaaac
    89341 tagatgagaa ctctaaagta ttattaataa gtacagaagg agatactgac cctgataaat
    89401 atagagatat agtttggaat ggtgaatgcc aaagtaaata aaagacttaa ggaaaagaaa
    89461 atcttaacaa ataaatgaaa aatttaagga aaataaaaac ttaaataagt gaaaacttta
    89521 aataaaataa aaactaaaac aaatgaaaaa tctaaataaa tgaaaaagta aagcaaataa
    89581 aaaagtaaag caaatgaaaa attcaaaata aaaactaaat aaaattaaat aaaaccaaat
    89641 aaaattaaaa taaagtctaa ataaaaattt aataaataaa atataaagaa ataaaaaatc
    89701 aatagattaa gtgaaatgct aataaattaa aaaagtgaaa tatcaaaata aaacgtcaac
    89761 aaattaaaaa ttatatgggg gaatatcaaa atgttaaatg aaacaagaaa aaaacaatta
    89821 actgaagtat gccaagactt aataagaaat gctagttatt caggtcaaga agaaaacgta
    89881 gtaaaagcta tagaagaaaa ttttgcttta ctaggttttg atagttggtc aagagataga
    89941 tatggaaata tagtaggatg tataaaaggt aacaagccag gtaagaaaat attatttgac
    90001 gggcatatag atacagttcc agttccagat gcaagtaaat ggagtgttcc tccttttgaa
    90061 gcgagaatag tagatgggaa aatatatggt agaggaactt ctgatatgaa ggggcaagta
    90121 agtgctatga tggctgctgt ttcatacttt gcagaagata ctaacaaaga ctttgaaggt
    90181 gaattgtatg tagcaggtgt tgttcatgaa gaaatatttg aaggtgtttc agctagagag
    90241 ataagtaagg ctgttcaacc tgattatgtt gtaataggtg aatcttcaga attaaaccta
    90301 aagataggtc aaagaggtag aggagaaata gtagtagaaa cttttggtaa accagctcac
    90361 tctgctaatc cagaaaaagg tataaatgca gtttataaaa tggctaatgt aatccaaaag
    90421 atacaacaat tagtacctcc aactcatcca gttttaggtg atggaatatt agttttaaca
    90481 gatataaaat cttctccata tccaggagca tcagtagtgc cagattattg caaagctact
    90541 tttgatagaa gattattagt tggagaaaca agagaaggcg tattagctcc aatacaagct
    90601 ttattagatg aaatgatgaa agaagaccca gaattaaatg caaaagtttc ttatgcagtt
    90661 gaaaaagctg attgctatac aggaaatact atagaaagtg aaagattctt cccaggttgg
    90721 ttatatgatg aagaagatga atttgttcaa gcagcgtata agggattaaa agaagctgga
    90781 atagattcag aaataactca atactcattc tgtacgaatg gaagtcacta cgcaggtgag
    90841 gctggaataa gaactatagg atttggtcct tctaaggaaa atcttgctca tacaatagat
    90901 gagtatatag aattagacca attattcaaa ggtgcagaag gatattatgg tatattaaaa
    90961 tcagtttata aaaaataatt aggagatggt tttgtgagaa ctttaataaa acatgggctt
    91021 atagtagatg gaaataaaac accagcatat gaaggagata ttttaataga aaacgagaaa
    91081 atattaaaaa tatcacaaga tttaaacgaa gaagctgaca aagttataga tgcaaaaggt
    91141 agagttatat gtccaggttt catagatact catagccatt cagacctagt tattttagtt
    91201 aatccatata atgaggtaaa gattagacag ggaattacaa cagaagtgtt gggccaagat
    91261 ggtatatcta tggcccctct acctcaagag catatatctt cttggagaaa aaatttagca
    91321 ggtttagatg gtgaaagtga tgaaattgat tggaaatatg aaacaacaga gaattattta
    91381 aaaatgatgg attacaatgg ggtaggttta aatgaaactt atttagtacc tcatggaaac
    91441 gttagaatgg aagctatggg acttgaagat agacctgcta ctaaagaaga aattcaaaaa
    91501 atgtgtgaaa tcacagagag agaattaaaa gcaggagcta taggattgtc tactggactt
    91561 atatatatac cttgtgcata ctcattgact gaagaaatta tagagatgtg taaggtagta
    91621 gcaaaatatg acggagtatt tgtagttcac caaagaagtg aagcagatac aattttaact
    91681 tcaatggaag aaatcataga aattggaaaa caatcaggag taaaagttca tttttcacat
    91741 tttaaggttt gtggtaaagc aaactggaag tatataccac aagttataga gcttttagaa
    91801 aaagcagaaa aggaaggaat aagagtatct tttgaccaat atccatatgc agcaggaagt
    91861 acaatgcttg gagtagtttt acctccttgg gcacattctg gaggaactga taagttaata
    91921 gaaagattaa gtgatgaaaa cgaaagagca aaaatgaaaa aagatatagc aaatggaata
    91981 gaaggctggg ataattttat agaatttgct ggaatagacc aaatatttgt aacaagcgta
    92041 aaaacagaaa agaataaaga tacaattggt aagagcttat tagaaattgg aaaaatgaga
    92101 ggaaaagacc cattagatgc aacgtttgat ttattaaaag aagaagaaaa tgcagttggg
    92161 atggtagatt tctatggatt agaagaacat ataataggat tcatgaaaag agacgagcaa
    92221 aatgtgtgta cagatggtct tttagcaggt aaaccacatc caagagctta tggttctttc
    92281 cctaaaatac taggaagata tgttagagag ttgaatgtgt taacaatcga agaagctgtt
    92341 tataaaatga ctaaaaaggc agctacaagc tttagtataa aagatagagg cgaattaaaa
    92401 gaaggatatt ttgcagatat agttatattt gacaaggata cagttagtgg ttgtgatgat
    92461 tttatcaact ctatgcagta ccctacaggt atagattacg taattataaa tggaaattgt
    92521 gttgttgagg aaggaaaata caataaaatt aaagcaggaa aagtacttaa aaattaaatc
    92581 ttagctttaa ggaggaataa atttatgatt ttagtgggga atgggaggct aataagccaa
    92641 gattctttaa atccctatat ggaagatgga tgtgtagtaa taaatgataa tctaattgaa
    92701 gatataggta ctacagaaga aatgaaagct aaatatccag tacatgaatt tatagatgca
    92761 ggcaagaaaa taatcatgcc gggtctaata aattcacata tgcatatata cagctcattt
    92821 gctagaggaa tggcagttcc aggaaaacct tctgagaact ttttagagat actaaacaat
    92881 ttatggtgga gacttgacaa acagcttaca ctggaagata caaaatacag tgcatatgca
    92941 acgtatatag aatgtataaa aaatggtgta acaacagttt atgaccatca tgcaagtcca
    93001 aatgcaattg aaggcagttt gtttacaata tcagatgttg caaaggattt gggaattaga
    93061 acgtgtcttt gttatgaagt gtctgataga gatggtggaa atacaatcca acaaggtatc
    93121 aatgaaaacg taaactttat aaaatacgct caaaaagatg atacagacat gataaaagga
    93181 atgtttgggc ttcatgctgc atttacacta tctgatgata cattaaataa atgtgcttca
    93241 gagatggctg gtcttgatac aggttaccat gtacatgttg ctgaaggact agcagactta
    93301 caatataatg tagataaata tggaaaaagg gttttagaaa gattcaatga ttttggagta
    93361 ctaaaagaaa aaacaatagc agttcattgt atatatataa gtgcagaaga aatcagtctt
    93421 ttaaataaaa caaatacatt tgtagttcat aatccagaat ctaatatggg aaatgcagtt
    93481 ggatgttctc ctgcaataga gttattaaaa aggggagtta cagtaggatt aggaactgat
    93541 ggatatacta gcgatatgtt tgaatcatta aaagttgcca atataattca caaacatcac
    93601 ttaaaagacc taagagttgg atttgaagaa tcacaaacaa tgttatttga taacaataga
    93661 aaaatagcta aagcttatta taaaaatgac ctaggagtac ttaaaaaagg tgcttatgca
    93721 gatgttatag tagttgatta tataccacat actccattga cagaaaatac aataggggga
    93781 cacactattt ttggaatgag tggaagaagc gtagatacaa ctattataaa tggaaaggta
    93841 cttatgaaag atagaaagtt aataaacata gatgaagaaa gtattctagc aaaaagtaga
    93901 gaattaagtc aaaatctatg gaatagaatt taaataattg atattaatat acaagtaaga
    93961 aacaagaatt tagatgttaa aaacagagct taaacaaaaa taggaattta aatgaagtat
    94021 ataaataaaa aatatacgga atagaatatt aaattaaata tagaagggag acccaaaatg
    94081 tctcgagata aaagccctaa aatagctcca gtagatgaaa ggttacctgt atccaaatct
    94141 tgggtatttt cactacagca cgttttagca atgtgtgcag gagcagtagc agttcctatg
    94201 atgataggaa gtgctgcacg actagatcat gctagtattg tttttttaat aaatgcttgc
    94261 ttgtttatgg caggtatagg aacactcata caaagtgttg gtataggaaa tattgtaggt
    94321 gctaaaatac cagtaataga aggaactagt tttgccgctg tggcaggtat gacagcaata
    94381 gcctcatcat atagtgattc acaagttgca atacagacag tatttggctc tgtaatagta
    94441 gctggattgt tttgtatatt acttgctcca gtatttgaaa aattaataag atttttccct
    94501 agtgtagtta ctggaacagt tgttatggta ataggtattt cactatttcc agttgggata
    94561 aaatggataa ctgacaacaa attagaagcg gttgaaccaa actcattagc attagcttta
    94621 gcagtattgg caataacttt actttcattt aaattcttaa aaggaatttg gaatagcaca
    94681 gctatattgg taggtatagt acttggtaca ctactttcca tggcagttgg aatggcagat
    94741 tttagtgcag taaatggagt tggttggctt aacttaaatg tacctttaaa atttggaatg
    94801 cctagatttg aaccatctgc aatactatca ttgtgtttga ttatgttggt acttatgaca
    94861 gaatcagttg gtaatatgat agctattcat gaaatggtag acaaagaagt aacaggtaaa
    94921 aatattaaaa gaggtctatt tggagatgga atatctacag cattatctgg aatattcaat
    94981 tcatttccaa taactccatt cggtcaaaat acaggaatag taggtcttac aggtataaaa
    95041 tcaagattta tagcagttta cgcaggggtt atattgctag tacttggatt cttaccaaaa
    95101 tttgcagcaa taataggagc aatacctaag cctgttcttg gaggcgtagg atttgcaatg
    95161 tttggaatgg taatggttgg aggagtaaaa actttaagca aagtgaaatt tgatggaact
    95221 aaaaatgggg ttatagtagc agttagtgtt ggtttgtcta tgataccact aacaaatcct
    95281 gatttctatc ataatttccc aacttgggta caaacaatat tccatagtgg aataacaaca
    95341 ggtagtttat cagcagtgct tttaaacata ttcttcaatg aactaggttc taaaaaagaa
    95401 aaaaataata aagttgaaga agcaaaataa aaataaaaca agtaaaaatc tatattgact
    95461 taaagtcatt aagtattaat aaaaataatt cagagatatt aataattcaa caaaactatc
    95521 ttatatttta aataatataa aaaagtaaat aaataacaaa tacaaataaa agaatacaat
    95581 ctaaatatta aaaatattta atttaaggga gagataataa tatggctaat ttaaaagtta
    95641 atttatatgg aatggaattt ttaaatccaa ttatgacagc ggcaggacct ggagcaaaag
    95701 atggtgctct ctgtcaagag gcagcaaaag gtggagcagg agctatatgt acaaaaacta
    95761 tatctgtatt accagctgat gtaccaagac catgtatggc aaaaactaat agtggttttt
    95821 taaacacaga attatggtca gagcttccaa aagagcaatg gatagaggaa gaatacaaaa
    95881 aggtaaaaga aacagggctt ccagtaatag taagtatggg atattcagca gagcaaatag
    95941 ctgaggttgc tcctttagta aagccttatg cagatgcagt tgaattatct actcattatg
    96001 taggtacaga cgttgcacca atagtaaatg ctttaaaagc tgcaaaagct gttttagatg
    96061 taccagtatt tatgaaaatg agtcctcata ctgacattca aactattgca aaagctgttg
    96121 aagaagcagg tgcagatgga cttgtaatga taaactcatt tggaccatgt atggcaatag
    96181 atgtaaatac aggataccct ataatgggaa gtaaagctgg atacggatgg ttatcaggtg
    96241 caccaataag acctctagca ataagatgta tatatgaagc ttctcaagtt gtaaatatac
    96301 caataatcgg tgttggtgga atcacttgtg gaaaagacgt ggctgaaatg atgatggctg
    96361 gagcaagtgc tgttcaagta tgtacagaag caatccttaa agggccttct atctatggaa
    96421 aaattgctaa agaattaaat gaatttttag atgagaatgg atatgctgat gttaatgaaa
    96481 taaaaggact aactcataag aaaatggcag ctagagggtt tagaactcat tcagtagctc
    96541 cagtagtgga tgataacaag tgtatcaaat gtaagcaatg tgtaacaagc tgtgtatacg
    96601 aagctttaga agttacagat aagttgaaca tagatgcaga caagtgtttt ggatgtggat
    96661 tatgtgtaac tagatgtcca aaaggagctt taagcatctg ctacaatcaa gtagaagcta
    96721 tgaatgagta ataattatat agaattttgg taattaactt agagtaatag gtattaggat
    96781 aataaaatat atcagataaa caaacacaca ttatgcatta ataatacagt ctaaagttaa
    96841 taattttatt atattgattt aactaaatat tagtttagct gaatattaat ttaattaggt
    96901 attggtttaa tcttaatata gatttactgc gtataagtga actaactaga ttactttaag
    96961 ttaatttttt catataaaat aaattgatac attacaagta aggtggagtc tatatgggaa
    97021 ttgttttaaa aggtgggaaa gtagtaacaa gtgaaaaaac ttactgtgca gatgtaagaa
    97081 tagaagatga aaaaatagtc gatataggtc ttgatatatc aaaagaaaat gatgaaatag
    97141 ttgatgttag tgattcttat gttataccag gaggtataga tacacacaca cactttgact
    97201 tagatacagg cgttactaag acagcagata actttgagac aggaacaaaa gctgctatag
    97261 taggaggaac tactactata ttggattttg ctacacaagc taaaggatgt tctttgaaag
    97321 acggattaga agaatggcat gaaaaagcta aggataaatc ctattcagat tatggctttc
    97381 atatggctat aacagattgg aatgactcgg tttgtaatga aatggaggat atggtgaaag
    97441 agggagtatc ttcatttaaa ctgtatatgg cgtataaagg aagccttcaa gttgatgatg
    97501 gtgtaatctt tgaagcattg agaaaagcag aagagatagg agggattatt ggtttccatt
    97561 gtgaaaatgg ggacataata tgtgaacttg tggataaagc aaagtcagaa aataatttat
    97621 ctccaaaata tcatcaatta actagaccag ctataatgga ggcagaagct acatcaagac
    97681 ttatgaagat agctgaagtt gcaaactcta aagtatatgt agttcactta agctgtaaag
    97741 aatccttaga ggaggtttta aaagctaagc aaagaggtgt ggatgtaata gttgaaactt
    97801 gtcctcaata ccttctatta aatgatgaat tatatgattt agatggattt gaaagtgcta
    97861 agtatgtaat gtcaccacct ttaagaaata aagaaaataa tgaaatatta tggaatgcta
    97921 ttttagataa tcaaatagac actataggaa cagaccattg ttcttttaat tataagggac
    97981 agaaggaact tgggataaac gatttcagta agataccaaa tggttctcca ggtgtagaac
    98041 ataggatgag tcttttatac acatatggag tctgtaaaaa taaaatatct atcaacaaga
    98101 tggtagaagt aacatcaact aatgcagcaa agttgtttgg aatgtatcct aataaaggaa
    98161 ctatagaaat aggcagtgat gcagatatat tagtcttaaa tccaaacaaa aaatccaaaa
    98221 tagaagcaaa aaaacaatta caaaatgtag attatacacc ttatgaaggg tatgaagtgg
    98281 attgtcaaat agaacatgtt tatttaagag gaaaagaagt agttagagat ggagaattaa
    98341 tttgtaatac tccaagtggg agatatataa ataggcgtct aacaaagggg gctagagaat
    98401 ggtagaattt atattaaatg gagagaaagt tgttgcaaaa gaaggcaaaa aacttttaga
    98461 cttccttaga gaagatatga atataacttc agttaaaaat ggatgttcag aaggtgcttg
    98521 tggaacatgt atggttataa tagatggtaa agctactaaa gcatgtgtat ttaaaactga
    98581 taaattagct gggaaaaaca taacaactat agagggatta tcagagagag aaagagatgt
    98641 ttttgcatat tcttttgcta gtcaaggagc tgtacaatgt ggattttgta ttccaggtat
    98701 ggtaattagt tcaaaagcac ttatagacgt taataataat cctactgaag atgatataaa
    98761 gaaagcttta aaaggtaata tatgtagatg tacagggtat gtaaaaataa ttaaagctgt
    98821 cgatttagcg gcaaagattt ttagagaaaa tatagatgtg ccaaaagtaa actgtaaggg
    98881 tctagtaggt gaaaatcttc ctagagttga tgcagttggc aaagcacttg gatattctga
    98941 atatgtagat gatatgagaa ttgagggtat gatttatggt tcagcagtta gagctaagta
    99001 tcctagagct ttagttaaaa aaatagatat agaagaagca aaagcttatc caggagttgt
    99061 tgcagttcta acagctaaag atattccagg aactataaag gtagggcact taaagaagga
    99121 ttgggatact ttaataccag aaggtgaaat aactagatac ttaggagatg gaatagtttt
    99181 agtagcagca gaaactagag aagcgttaga agaggccaaa aagctagtta agatagatta
    99241 tgaggaatta acaccattaa gtactacagc agatgcactt agagaagatg ctccaaagat
    99301 acatgagaca gggaatatac ttgttaagga acatttagta agaggaaacg ctaaagaaaa
    99361 gatagaaaat tcaaaatatg ttgtaactaa aagatatact acacctgcta cagaacacgc
    99421 atttttagag cctgaatgtg cagtagctgg tccttatgaa gatgatggag taataatcta
    99481 ttcgacagac caaggggtgt ttgccactca acatgaatgt gcagatatgt tagggttacc
    99541 atatgagaag gtaagagtta taaacaaaat ggtaggagga gggtttggtg gaaaagaaga
    99601 catgagtgtt caacaccatg cagccttact tgcataccat acaaagagat ttgtaaaagt
    99661 acagttaaca agaaaagaaa gtattattgt tcatccaaaa cgacatgcca cagaaatgga
    99721 atttacgaca gcatgtgatg aaaatggata cttaacgggt atgaaggcaa cgataatatc
    99781 tgacacaggt gcatatgcct ctcttggagg accagtgcta caaagactgt gtactcatgc
    99841 agcaggacca tacaattatc aagatattga tataacagga acagcagtat atactaataa
    99901 ccctcctgga ggagcattta gaggatttgg agttacacag agttgttttg caactgaatg
    99961 taatctaaat ttacttgctg aaatggttgg aatatctcct tgggagataa gatataaaaa
   100021 tgcaataaga cctgggcaag ttttaccaaa tggtcaattt gcagatgaag gaacagcaat
   100081 ggcagagaca ctagaagctg taaaagaaga gtatgaaaag catccacgtg caggtatagc
   100141 ttgtgctatg aaaaatagtg gggttggagt tggtatacct gatgttggaa gatgtagatt
   100201 ggtgataaaa gatggcaaag ttcacataag aacaagtgct tcttgtatag gtcaagggct
   100261 tggtactgtt atgactcaag tagtttgtga aactgctaac ctacttcctg aaaatatagt
   100321 tcatgaagtt ccagatactc atttaacacc agactctggt aatactacgg cttcaagaca
   100381 gacagtattt acgggagaag ctactaaggt tgcatcaaat aagttaaaag aagctttaga
   100441 ctctggcaaa actttacttg atttagaggg agaagagttt tatggagaat atgaaagtat
   100501 tacagataaa atgggttgtg acaaagaaaa tccagtaagt catgttgctt atggatatgc
   100561 aacacaagtt gtaattctgg atgaaaatgg aaaactagaa aaagtagtag cagcacatga
   100621 tgttggaaga gctataaatc caatcagttt agaaggtcaa atagaaggtg gagtagttat
   100681 gggtcttgga tatgctctaa ccgaagatta cccagtagtt aactctattc ctacagctaa
   100741 gtttggtaca ttaggtttat ttaaatctac agatatacca gaaatacaag ctttaatagt
   100801 tgaaaagaac aaagatttat tggcttatgg ggcaaaaggt gtaggagaaa tttgtacagt
   100861 tcctactgca ccagcagtac aaaatgccta ttatgtattt gataaagaat ttagaactga
   100921 gttaccacta caaaatactc catatagtaa aaaaaagtaa caaaaaaaag aaatattaaa
   100981 taaaaaaata gatgaaattg taaataaaaa aaaccctttt gcataaggta tattttaaat
   101041 gatagaatat acatatacag gagggttttt cttttataaa ataagtttaa taaaattgag
   101101 aggtgagcag aatgaatttt aataatagtc tagaattaac tcagtctcag aagctaataa
   101161 tgactacaca acttaagcaa tcattatcaa tattaaatat gagtaagtta gagttagaag
   101221 aagagataaa aagagaagca gagaataacc cattagttga agtcgagaaa agtggggaga
   101281 taaattggga agagtatata aaagacatgg ataggtcaag acgtttagat agaacagaga
   101341 taagctataa tcctgataat gaagttaatc tagaaaattt agttaaatat tcgtcaaatt
   101401 tatatgaaga tttaaaattt cagataagcc tgtataaact tacagacaaa gaattggaag
   101461 tctgtgagta tataattgat agtttagatg aggatggata tttaagaact gaggaaaaag
   101521 taattgttga taccttaaag atagatgaag aactttttga aaaatgttta attagtgttc
   101581 agcagttgga acctagtgga gtaggggcaa gaagtctttc agaatgtctg atgatacaaa
   101641 tggctagttt aggaatatat aatgaaattt tagaggaaat cgttacaaaa gacttaaatt
   101701 taattgcaaa taataaatac aaagagataa gtaaaaagta caatatgtca ttacaaaaat
   101761 gtgttgaact aataaacata attaagacat tagaccccaa accaggaaga acttgttcag
   101821 tagagaaaag tgtatacatt caacctgatg taacagtaga aaaaattgat gatgaattta
   101881 ttgtatattt aaatgagaaa gattcttatc aaataagaat caatagttat tataaagaca
   101941 tattaaaaaa ttcacagtct gatgaaagtg caaaagaatt tataaaagaa agactaaatt
   102001 cagcaacagg acttatgaaa aatatagaga gtaggaaaac tacagtactt aagattgcag
   102061 aagagatagt aaaagctcaa gatgaatttt tgagaaaagg gacaaaatat ataaaacctt
   102121 tgaaaatgaa agacatagca gaaaaattag aatttcatga atctactata agtagaggtg
   102181 taaatggtaa atatatgcta acaccttttg gcgtatatga atttaggtac tttttcagta
   102241 gcgccattga gactgagaat aatgaaatgg catctagtac aagcataaaa aaaattataa
   102301 aggaaacaat aaaagacgaa aataaaaaga aacctttaag tgatgaccat atatctaagt
   102361 tattaaaaga aaaaggaatc aatgttgcaa gaaggacagt tgccaaatat cgtgaagaat
   102421 taggaatccc atcttcaagt aagagaaaag aatactaata agtaaaagac aaatatcagt
   102481 atggtaaggg gaaaaggcta attaagagat gaatgtagat tgggctaaaa attttataaa
   102541 gtaaaataat ataatatgaa aaagtattaa aatgctataa ggtattaaaa aactggggaa
   102601 cattaaaaca ttaagatagc aaagagcata aaaaactaaa gaagattaaa acattaaaga
   102661 acattagagc tttgaggaat attagaactt taaagaatat taaaatttat aaaatataaa
   102721 aatactaaaa agaattgaaa aactggggaa cattaaaata ttgtaaaatg ctaaaaaact
   102781 agaaaacata attaaataag tgcttataaa gaatgattaa attaaataag tgtttgtaaa
   102841 gaataattag atattagaaa aagaagaata cctagataaa taaactatta ttaaatttaa
   102901 taatcacaaa aggaaaacac gtagggtata aataaaaatc ttaactagat aaaagtaaac
   102961 ttagttgtag ataaaaataa ctagaaataa aattatttat agtaataaat attagaatga
   103021 aaatataaaa aaatatatat aaaaagcctt atataaaaag aaaaaatact gtgatttgaa
   103081 aatggtggag aaatatttta taaaataaaa aaataaaaaa gtttttgaaa aactattgaa
   103141 atctatacgc aaatcctata aaataaaaat atcttgtggg acttaaataa acactaggga
   103201 caaaaaaagt cccgaaagga aagcaataag gagtatgtta tgaagaactt attagaaatt
   103261 caaaagaaat tgattccaca ggcaattgaa cttatggaaa gaagatactc tattttaaga
   103321 caaatatctt taagtgaacc aataggtagg agaacattat caaatgtatt agagattagt
   103381 gaaagaataa tcaggtcaga aactgagttt ttaaaagaac aaggacttat agacgtagct
   103441 gtatctggga tgactatcac taaagaaggt tctgatttgt tagataaact taaggacatc
   103501 atgagtgaca tcatgggatt gtctaagtta caagatagag tcagagaaaa gcttggaata
   103561 aaaagggtaa tattagttcc tggaagctgt gatgaaaatg gaagtttact aaaagatgta
   103621 actagatatg gatgcgaata tttcttaggc attttaaaag atggagatat cgtttcaata
   103681 acaggaggaa gcactatgtt ggagttttca aacgttatta aaactgataa gagatatcca
   103741 aactctacaa tagttccagc tagaggaagt atgggaactg atgtagagat gcaatctaac
   103801 aatatagttg cttcaataag taagaaatta cattctaatt gcaaactttt acatatacca
   103861 gatgagttgg atgaaagtgc aatgaaaact cttagccaag tgccagagat taagacaact
   103921 ttggagtata ttaaaagaac agacatttta gtttttagta taggtagagc agatgtcatg
   103981 gcaaagagaa gaaaacttcc agaagacaag gttgatgaga tattatctaa aaatgcagtt
   104041 ggagaagcat ttggatatta tttcaacaaa gatggagaaa tagtttacaa actgaacact
   104101 gttggaattg atttagaaac agttaaacaa gtaaaagaaa ctattgcaat ctttgcaggg
   104161 actgaaaaag tagaagcctt attagctata tcaaatatgc ataaaaacat ggttcttgta
   104221 acagatgaag aaagtgctta taagatattg tcattattat aaaagtcaag acctagcaca
   104281 gagctagaaa acatacattt actttatagg aggtagcgaa aatggttaaa gtagctataa
   104341 atggatttgg aagaatagga agattagcat taagaaaaat gatggagcaa caagataagt
   104401 tcgaagttgt tgcaataaac gacttaacag acgctaaaat gttagctcat ttatttaaat
   104461 atgatacagc tcaaggaaga tttaacggag aaatagaagt taaagaaggt gcttttgtag
   104521 taaacggaaa agaaataaaa gtaacagcag aaagaaatcc tgctgaccta ccatgggctg
   104581 aattaggagt agatatagta ttagaatgta caggattctt tacatctaaa gataaagctg
   104641 aagctcatat acaagcaggg gctaagaaag ttgttatatc tgcaccagct actggagatt
   104701 taaaaacaat agtattcaac acaaacagtg acatattaga tggttctgaa acagttatat
   104761 caggagcttc ttgtactact aactgtttag ctccaatggc taaagtatta aatgataaat
   104821 acggtataga aaaaggctta atgactacta tacatgcata cactaatgac caaaatactt
   104881 tagatggtcc tcatccaaaa ggtgatttaa gaagagctag agctgctgct ggaaacatag
   104941 ttccaaacac tacaggagct gcaaaagcaa taggcttagt aataccttca ttaaaaggaa
   105001 aattagatgg ggcagcacaa agagtaccag ttgtaactgg ttcaataact gaattagttt
   105061 gtacattagg aaaaaatgtt acagttgaag aaataaatgc agctatgaaa gaagcttcaa
   105121 acgaatcttt cggatatact gaagaaatgt tagtatcttc tgacataatc ggaataagct
   105181 acggttcatt atttgacgct actcaaacaa aagttatgga agtagatgga aaacaattag
   105241 ttaaagttgt ttcttggtat gataatgaaa tgtcttatac ttctcaatta ataagaactt
   105301 taggatactt tgcacaatta gcaaaatagt cagttttgag aaaatagaaa agtagattga
   105361 caaagtccga gtttgtagtt taatactacg gactcaggac tttttttaag aaaaaatata
   105421 taaaatacac ctaaataatg ttacatacta tatataaaaa tatgataata tgatatattt
   105481 aatagggtaa aagtatgtac tatattatac ttggcaataa aaaattactt tattaaaagg
   105541 agagatattt atgtcaatgc ttaacaaaaa aactatagaa gatattgatg tgtgcggaaa
   105601 aaaagtatta gtaagatgtg actttaatgt gccattacaa gatggtgtaa ttactgatga
   105661 aaatagattg aacggagctt taccaactat tcaatattta atttctaaag gggcaaaagt
   105721 tatattatgc tctcacttag gaaagccaaa aggagaagct aaaccagaat tatctttagc
   105781 accagtagca aagagattat ctgagatgtt aggaaaagaa gttgtatttg cagcagacga
   105841 taatgttgta ggagaaaatg caaagaaagc aactgaaaaa atggaaaacg gagatgtagt
   105901 attattagaa aatactagat atagaaaaga agaaactaaa aacgaagaga atttctctaa
   105961 agaactagca tcacttgctg aaatatttgt aaatgatgca tttggaactg ctcatagagc
   106021 acattgctca acagttggtg caggcgagtt tttacaagag agagtttgtg gatacttaat
   106081 tcaaaaagaa ttaaaattct taggagaagc tgttgcaaac cctgtaagac catttacagc
   106141 tatacttgga ggagctaaag tttctgataa attagctgtt ataaacgaat tattagaaaa
   106201 agttgataat ctaataatag gtggaggaat ggcttataca ttcttaaaag ctcagggtta
   106261 tgaagtagga acttctttac ttgaaataga taaagttgaa tatgctaaag aaatgatgga
   106321 aaaagctaag aataagggtg ttaacttatt attaccagta gacgttgtta tggcagacca
   106381 ctttgcacca gatgctactc caatagtaac agaagatgct aatgtaaaag aagattacat
   106441 gggactagat atgggaccta agactatagc aaactttgta aaaactataa aagaatcaaa
   106501 aactgtagta tggaatgggc caatgggagt atttgaattt gaaaactttg caaatggtac
   106561 attatcagta gctagagcta tggcagagtt gactgatgca actactgtaa ttggcggtgg
   106621 agatagtgca gcagcagtta atcaattagg atttggtgac aagatgactc acgtatcaac
   106681 aggtggagga gcatcactag aatttttaga aggtaaagaa ttaccaggta ttgcagcatt
   106741 agataataaa taaactaata tatagaggag attgtaaaat gagaaaacct ataattgcag
   106801 gaaactggaa aatgcataaa acaataaaag aagctttaga atttgtaaat gaagttaaag
   106861 ataaagtaaa ttctgataaa gtagaagctg ttatatgtgc accatttact ttattaaagg
   106921 atttaaaaga agctactaag ggtacaaata taaagatagg tgctcaaaat atgcactttg
   106981 aagaaaaagg agcatttaca ggagaagttt cacctcttat gttaaaagaa atagatatgg
   107041 actatgttgt aataggacat tcagaaagaa gacaatactt caatgaaact gatgaaactg
   107101 taaacaagaa agttttaaaa gcattagaag taggaataga cccaatatta tgtgttggag
   107161 aaactttaga acaaagagaa gctggaaaaa ctaaagatgt ttgtaaagtt caagttgaaa
   107221 aagctttaga aaatgttctt aaagatgatt tagcaaaagt agttgttgca tatgagccaa
   107281 tctgggctat tggaactggt aaaactgcaa ctgctgaaga tgctaatgac gttatatctt
   107341 atataagaga agttataaaa ggattatatg gagaattagc taatgaagtt agaatacaat
   107401 acggtggaag tgttaaacct tcaaatgtag ccgaaataat gggtcaaagt gatatagatg
   107461 gagctttagt aggtggagct agtttagcta gtaatgatta cctagacctt gttaatttct
   107521 aaggagtgaa atgatgaaaa aaccagttgc tttaattatt atggacgggt ttggatacaa
   107581 taaggatgtt aagggaaatg caattgctga gtccaaaact cctaatttag atagaataaa
   107641 aaaagagtat ccaaacacat tgataaatgc tagtggtctt gatgttggtc tacctgatgg
   107701 tcaaatggga aattcagaag ttggacacac taacataggt gcaggtagaa tagtatatca
   107761 agatttaact agaataacaa aatctataaa agatggtgac ttttttacta ataaagtttt
   107821 atgtgaagca atggataatg caaaagaaaa ctctcttcat gtaatgggac ttttgtctga
   107881 tggaggagta cattcacata tagaccatct taaggctata atcaaaatgg caaaagataa
   107941 aggcgtacaa aaggtgtatg ttcacgcatt tactgatggt agagatactg accctcaaag
   108001 tgcattagaa tatgccaaag aagtacaagc tagtatggat gaaattggag taggtgaatt
   108061 tgctacagtt tctggtagat actacgctat ggatagagat aagagatggg aaagagtaga
   108121 acttgcatac aatgccatgg ttagaggtat tggtgaaaaa gcaaattcta ttgaggaagc
   108181 tattcaaaac tcttatgatg atggaaaaaa tgatgagttt ataatgccaa cagttattat
   108241 gaaagatgat aaaccagttg gaagtataaa ggaaaatgat tcaattatat tcttcaactt
   108301 tagaccagat agagctagac aaataactag agctttagtt tgtgaagagt ttgatggatt
   108361 taaaagagaa gatattaaaa acttctttgt atgcttaaca gagtacgata taactataga
   108421 gaatgtgcat atagcatttg gacctcaatc tttagccaac actctaggtg agtatctagc
   108481 taaaaatgga aaaactcaac ttagagctgc tgaaactgaa aagtatgcac atgtaacttt
   108541 cttcttcaat ggtggagtag aagagccaaa taaaggtgaa gaaagactat tgataccttc
   108601 tccaaaggtt gcaacttatg atttaaaacc agaaatgtca gcatatgaat tgacagataa
   108661 agctttagat aaattaggag aagataagtt tgactttata gtattaaact ttgcaaatcc
   108721 tgatatggta ggtcacacag gaagtataga agcggctata aaggctgttg aaactgtaga
   108781 tacttgtgta ggaagattga tagataaaat agtagagtta ggtggaagtg caataataac
   108841 tgctgaccac ggaaatgctg aatatatgtt agacccagaa acaggaaaaa ctgtaacggc
   108901 tcactctatt aatccagtac catttattgt agttggtcaa gaatatgaaa gtgcaaaatt
   108961 attggatgga ggaagattat ctgatatagc acctactatt ttagatatga tgaagttaga
   109021 aaagccagaa gaaatgactg gtcattcact tatttcaaaa tagtcgattc tgataagtag
   109081 ataataatat ataaactaca atataaattt aaaaataatg cagtttaggt ttattttgta
   109141 aagtttagac tttatgacat aaggtttaaa ttttgtaagt tctggatatt gtaaggtgta
   109201 gatgaagata tattttataa aatttacaag atagacaatt tataaaataa aaaattacaa
   109261 tatagataat aatgtaaata atgatataaa taataacaag atagacaata acaatataaa
   109321 taataataat taatatatat tatataagca aaaattttag aatcattagt tgtacatttt
   109381 atgtttaatg ttttaaatct agttataata tttgtgtatt taagattggt tttggatttt
   109441 agacaagttt ttttatatta tataaattaa aatattataa aaaataaaat aaaaatagga
   109501 acttttacaa atttacccat caaataaatt tgtacctaat tttcaaaagc aactttatgt
   109561 actataatat agaaagtaga ttaaaatagt agacggatgt ttacagtaaa tgaaaattta
   109621 actaatagaa aatcgaaggg agatatacaa atgtcagtta ttgaattagt atatgctaga
   109681 gaagtattag actcaagagg aaatccaact gtagaagttg aagtagtatt agaagatgga
   109741 gcaatgggaa gagcaatagt tccatcagga gcatctacag gagcttttga agctgttgaa
   109801 ttaagagatg gagataaggg aagatactta ggaaaaggtg tagaaacagc tgttgctaac
   109861 gtaaatgaaa taatagcacc tgaaatagaa ggaatggatg catttgacca accagctata
   109921 gatgcaatca tgatagaatt agatggaact ccaaacaaag gtaaattagg agctaatgct
   109981 atattaggtg tttcaatggc agtagctaga gcagctgctg atgaaatagg tttaccatta
   110041 ttccaatacc taggtggagt aaatgctaaa caattacctg ttccaatgat gaacatatta
   110101 aacggtggag agcatgctga taacaacgtt gatgttcaag aatttatgat attaccagta
   110161 ggagcttgtt gtttcaaaga aggtttaaga atgggagcag aagtattcca ttcgttaaag
   110221 aaagttttag gagaaaaagg attagcttgt ggtgtaggtg acgaaggtgg atttgctcca
   110281 aacttaggtt caaacagaga agctttagaa ttaatagttg aagctataac aaaagctgga
   110341 tataagccag gtgaagacgt tatgttaggt cttgacgttg ctgctacaga aatgtacaac
   110401 aaagaaacta aaaaatacgt tttagcagga gaaggaaaag agttaactgc tgctgaaatg
   110461 gttgctttat atgaagattg gtcaaacaac ttcccaataa taactataga agatggttta
   110521 gacgaagaag attgggatgg atggaaatta ttaactgaaa aattaggaaa taaattacaa
   110581 ttagttggtg acgacttatt tgttactaac acagagagat tagaaaaagg aattgaaaat
   110641 ggagtagcta actctatatt agttaaagtt aatcaaatag gtacaataac tgaaacttta
   110701 gatgctatag aaatggctaa gagagcagga tatactgctg ttatatctca cagatcagga
   110761 gaaactgaag attctactat agcagattta gctgttgcag taaatgctgg tcaaataaaa
   110821 actggtgctc catcaagaac tgatagagtt gctaagtaca accaattatt aagaatagaa
   110881 gaaatggttg gagagcaagc tagatattgt ggattaaaat ctttctataa cttaaaaaaa
   110941 tagttattaa aatggttact aaaaaagatt aatgaagaga gaatataaga tatttaagct
   111001 catcttataa gatataaaag agataagtgt taattgattt ttcaattcac ttatcctttt
   111061 ttatatttta ttacttaatt ttattcatag attcagaaaa aatatgaata aatgtttcta
   111121 tctcattttt atctaattgc ataggaggtt tttattaaaa aataaaagtg aagacatatt
   111181 ttgatttaat cataattgtc attgaagtat tattgctaaa tgtggattat ttattttaaa
   111241 ttatgttgaa attaaaagtt atatcaatat tttaaaatga ttgttttatt ttggtggcta
   111301 tttataatat atacaatgag agtagattat tttaagtgtt aatttatgta ttaatttaaa
   111361 tagttttctc ttctaagttt tattcatttt tatattgaga atatagtaat atattatagt
   111421 aacaatatat ttttttgtat gttatttata gcataatagt cttgaaatgg ctatattatt
   111481 gtgatacact aaagagtaat gaaatttaag taataaacag ataggagggg caagaatgag
   111541 caacatttta atgggtgtgc aagtagtact agggatttta ctagtaatta gcataatgcc
   111601 tcaagattct aagaatgctt taccttcaga atttggtgga gaaggaagtc aagcttactt
   111661 taaaccaaaa ggaaaacaag catttcttgc tagagttaca aagataacag cagtattatt
   111721 ttttataaat gcattggcat tacttatagt taagaagtag tgatattgtt gaataactgg
   111781 ccattattta attagtgcat ttgctagaca tttaaaaatt aaatttagtt tttaataaaa
   111841 gtacatcaac ataaaaagta cgtaaaataa aagctggact aatgatttta tatgattagt
   111901 ccagttttta ttttatagat tgactatttg ttggcgttta ttatttgtat ttatatattg
   111961 tttgtattta tatatttttt tcaaactaaa aaatatatag caacactact ttcaccatgt
   112021 ttaatgagat aatatacaca aagttatatt atatagtaaa aatagtataa taatatgttt
   112081 ttacgcaatt aaatcgattt tatatatgtt tctcataata ccaatttgtg ttatcaaata
   112141 tcattaaata agattattct gctttaaaat aaatattatt aaaaatactg taattataga
   112201 aaatccagaa gtaaatacta caatttgtcc agctaattca ctgtcagaat ccatctgttg
   112261 tgccattgta aatgaagaaa ctgcagttgg agcagataac attatcataa gtgaagctaa
   112321 ttctacattt ctaaatccaa gaaaaatgct aattggtaaa aatatagcag gtacaagtat
   112381 aagttttcca catacgccca atataatggg gtttatatgc ccctttatag cagaaaaact
   112441 aaaagagcca cctagaatta taagtgataa aggagtagct attttagaaa tatcaccaat
   112501 agttttgtgt aaaaatgtag gtatattaat atttaaaatt agcattgtca atcctataaa
   112561 agaggcgatt atgagtggat ttgttaagac gcttttaatc atatgtttta tatttacttt
   112621 gccacctcta aaaatttcaa gaattacaac agataataca ttaaacatag gtacaataac
   112681 tgcaattaat aaagatgtga ctccaatact cttatcgcca aatagtgaaa ttgtcacagg
   112741 aataccaaat ataacgaaat tgctacgaaa tacaccttgt attaatgcac cccttgtctt
   112801 attatctttt tcaattttag gaataataaa gactaagatt aagaagattg aaaaaataat
   112861 tataacagct acagccataa gcttaaaatt aagagaacca tctaaatctg tattgtatat
   112921 attaaaaaat aataataatg gcaagaaaga cttgaagcag acattattca ttttatttaa
   112981 agtatgagta tcaaatagac ctaatttttt tagaacatat ccaagtgaca ttgtgagaaa
   113041 caaaggaaga acaacattta ttgataggat taaattttcc aaggtttact ctccgtgatt
   113101 ctatgatttg ataattcaat taaatttcca ttagtttttt tcaaataaat agatttcata
   113161 ttaccaaaga cacctgtaca ttctacaatt cctcgctcaa tttgaatctc attttgttct
   113221 aagtattttt ttggctcatc aatatttgtg tttattttaa aacataagtt atctctactt
   113281 gcttttgaat ttttaacata aggtaaaaat ttataacctt ttatgttaag atttatctta
   113341 acatttctag cattaagttt ataatttttg ctcatttctt tagatgaaaa accaaatttt
   113401 ttataaaaat tgatataatt ttctatatta ttattggtaa tgaccacatg ttctattttt
   113461 tttatcatgg caactcctta agattttata taaattagtt aaatttatat aagttattaa
   113521 attttatata gattgatgat atttatataa attattaaat tttatatagg ttgataatat
   113581 ttatataaat tactaaattt tatatagatt gataatgttt atataaatta ttaaatttta
   113641 tataagctat tgaattttat gcagattatt gtatttcatt tagattataa aactttatgt
   113701 agagttaatg aatttaacat atattattag ttatattagt gcttttattt taatgagtct
   113761 aataataatt ctaatagaaa ctgaaataga taagtaagtt ttaagctaaa atcaatttat
   113821 ataaattgat aataatctaa tataaattaa aataccagtc aactaaaata tatattaaga
   113881 taaagtgcag aaaatattct aataacaatt aagctaatca tcaattaaat gtagcattta
   113941 attaatgatt agctatagtc aacctaatta attagaataa cttcctttta gtgtaaatgt
   114001 atctaaaaca tgcccttcaa tagctttgaa aaattcattc atatagaatc ctttttcaag
   114061 gtcaagaata gtatcaagtg caaatacatg tatttcatag acatgaggtc tgtctggagg
   114121 agccattcca ccatatacac tggcctctaa tctgtcaaga cctcctagtt tgccatgcca
   114181 actagtagtc ccttgtacaa aatcagtagc tgttacactt tcattttcat ttaactcatc
   114241 ttttgttata tttacagcta accaatgtat ccatgcaaac ccacatacag gaacagagtc
   114301 tttatcttct aaaaatacag caaaggatac tgtattcttt ggagcatctt caaactttag
   114361 aggtagtgaa tatgtaggca taccaccttc attgaactga gttcctcttt taccgtattt
   114421 atcttctata acaccattta ctatacctgt actagttact ttcataataa tttacctcct
   114481 attataataa attaatagaa tatatctata atttaattat ataccagttg aaaataatgg
   114541 taaattactt acttttttgt gggtatctat ttactttaaa acaccttttt ccttaagaat
   114601 atcttccata ccattatcca acataaagct aattcctata tcttgcatta tagccaaagc
   114661 atccaatatt tgtttccctc gaataggtgt aagtgagtat tcaactttaa gtgggtaacc
   114721 ttcatatgtc tttttatcta caagaccaaa ttcaattaat tctttaagtt gttcaagtaa
   114781 catcttttga ttaataccat tgatttcctt ttcaagtttt gataaggaag ttggtcctat
   114841 gcgtaatctc cataatataa tagatttcca tttgcctttt atcatatcat gtgttagttc
   114901 taatgggcaa gtatactcat cacgaagttt caaataagtt cacctccatt ttactttgcc
   114961 aagatacatt ttgaagcaag cttatataca aactcaactt ttttatttga tatatcccat
   115021 gaatctaatt ctttttttac taaatctgga tattttttac ttatgtttct aagagcatta
   115081 cctacagact ttctcaagta ttcgctacca tcttctttta aactagaaag tagtgatata
   115141 gcaacgtcag gattagattt aaaatagtct ctactagtcc aaattcgaag accttctgtc
   115201 acagcccttt ttatgtttgg actatcagaa ttaagccatt cttttataac aggaagagcc
   115261 ttttcatatc ctacttcact gcaataataa tcaaatgatt tagctagtat ttcttgtact
   115321 ctccagtttt catctttact cacattatct tttaaaaata acaaagcttc agaaatagtt
   115381 actgatataa aaccaagtat aaacacagcc aattctctta cttgataata ttctgaccta
   115441 tataagtaga ttgatagata ataacacttt tttgagtcat tattttttac aattttttta
   115501 gcaatgtttt caatttcttt gaatccattt tctatagtaa taatttttgc aattacttct
   115561 tccaatttta tctcctccaa taaatagatt agtttaaatt ttatgtattt atttgtaaaa
   115621 aagtttgttt aatttagaca aaataaagac ttgtcaaaaa acgtttgcaa gtctttagta
   115681 ctagcataaa taaaaaataa taaaaaatca acctcattta acatataaat ttacttttat
   115741 tataagtttt atattataaa gttgtattta aaaaattaat tgagttatat aaattttaca
   115801 tgatttgagt atactaatag aataaattat tatatagtaa tacttatatg agatgaatat
   115861 tttaccaatc ctatttgatg gtgtataatt aggtgataaa gagtaattta agcaattatg
   115921 ataaagaata acttaagtaa ttataatgat atttacaaat aatttataaa acatcataat
   115981 ttgtttgaag ttagtatgac aaagcttaca ttaaatcaaa aatataaata agtaatttta
   116041 acttgtaata ataataagga aatatagaaa attatgtgat aagtaaaaaa tgttttgtct
   116101 gaagaaatat aaaagacaat ataaataata atataatgaa aagtaaaaca ggagggaaaa
   116161 atgataccag gacttaaaga aagtttgcta ggattaataa atgaaagtgc atataatcct
   116221 ctaaaaaaag aagaattagc agaaatattt gatatacatt catcagaaat gccaatgttt
   116281 tataattttt taaatgaatt agaagaagat ggttatatct gctttactaa aaaaggaaaa
   116341 atagtatctc ccaatcaaat gggatacttt gttggaaaat ttgtatcaca caaaaagggt
   116401 tttggatttg tagaatctga tgttgaatat acacaggatt tatttatctc aagtgacaat
   116461 ataaatggtg ctatgcataa tgatagagtt atggcagaaa tagtagtacc tgcaactgaa
   116521 gaaaagagag cagaaggaag aatagtaaaa gtaataaaga gagaaataac tagaatagta
   116581 ggtactttcc aatcaagtaa aacttttgga tttgtaacac cagacaacaa gaaatttact
   116641 aaagatatat atatacctaa aaaacatttt agtggagcag tagataatga taaggtagta
   116701 tgtgaaatta cagtatggcc acaagaggat agaaaaccag aaggcaaaat tatagagata
   116761 ctaggtcaaa aaggtgaaag aggcgtagaa atagattcta taataagaga acatggtctt
   116821 ccagaagaat ttccaaagaa agtattgcaa gaagcagaag ctgtagctgt tgagattcct
   116881 caagaagaga taaaaagaag aagagattta agagatttaa acatatttac tatagatgga
   116941 gatgacgcaa aagacttaga tgatgccata tcaatagaag tattacctaa tggaaacttc
   117001 aaactaggag ttcacatagc tgatgttaca cattatgtaa gagagaaaaa taaacttgac
   117061 aaggaagcct taaaaagagc tacatcagtt tatttagtag ataaagtaat tccaatgttg
   117121 ccaaaaactc tttcaaatgg agtatgtagc ttaaatccat ttgaagataa gctaactctt
   117181 tctatattta tggaaataga ccataaagga aatgtggtta aacatgaaat atgtgaatct
   117241 gtaataaatt ccaaagctag aatgacttat acagaagtat ctgatatatt agaaaaggat
   117301 gatgaaaaac ttaaaaagac ttttgaacat gttgttgaag attttaaaaa tgctgaaatt
   117361 ttagctagga ttcttatgtc aagaagggaa aaaagaggag ctatagactt caatttccca
   117421 gaggcaaaga taattctaaa tggaaaaggc gaagttgtag atataaagcc atatgaaaga
   117481 agaatatcta ataagataat agaagaattt atgcttataa gtaatgagac aattgccgaa
   117541 catttttact ggatgggaat accatttgtg tatagaatac atgagacacc atctttggaa
   117601 aaaatggaag aattgagtaa gtttatatct acatttggat atataataaa aggtgataaa
   117661 gaggaagtac atccaaaagc attacaaggt ataatagaga aaataaaggg caaaaaagaa
   117721 gaaggagcta tcagtactat aatgcttcgt tctttaaaac aagctaagta ctcaccagaa
   117781 tgtagtggac attttggatt agcagctaaa ttctactgtc actttacttc accaataaga
   117841 agatatcctg accttcaaat tcatagaata ataaaagaat ctttaaataa taaaataagt
   117901 ggaaaaagac aagaacagct tactactata gtggattatg catctgttca atcatccgag
   117961 aaagaaagaa aggcagagtt agctgaaaga gatgtacatg atttctataa ggctctttat
   118021 atgaaggata aagttggtca agaatttgag ggtgttgtat ctagcgtaac ttcatttgga
   118081 atatttgttg agttagataa tactatagaa gggttgataa gacttgcaaa tatgaatgat
   118141 gattactata tttatgatga gagttcttat agtgttttag gagaaagaac taagaagtca
   118201 tataagatag gagaccttgt taagataaag gttgaaagtg ttaatgtaga ttttaaagaa
   118261 attgactttg agatagttga aaaaatagag gagtagataa aacagctaaa ataagagata
   118321 acaagttgta gtatttatga tatgtataaa tatatagtgc acaatactct ataaaataaa
   118381 tgataaaaat aggtaattga gaaatatcta atggaaatag ttaactgaaa gataaataat
   118441 taagaaatat ttaatgaaag tagctaattg aaaaataagt aattgagaaa tgtttaatag
   118501 aaagagctaa ctgaaagata agtaattaag aaacgtttaa tagaagtggc taattgaaaa
   118561 ataagtaatt aagaaatgtt taatagaagt ggctaattga aaaataagta attaagaaat
   118621 gcttaataga agtggctaat tgaaaaataa gtaattgaga aatgcttaat agaagtggct
   118681 aattgaaaaa taagtaatta agaaatgttt aatagaagtg gctaattgaa aaataaataa
   118741 ttaagaaatg tttaatagaa gtgactaatt gaaaaataag taattaagaa atacttaata
   118801 gaagtggcta attgaaaaat aagtaattga gaaacattta atagaagaag ctagctgaaa
   118861 gataagtaat taagagatat ttaatgtaaa cagataattt aaaaatacct aattaagaat
   118921 agatattaaa aaatataatt tcaatataaa aataagtgta tcatttaaaa tttaagatac
   118981 acttattttt tatttaagat aacttttctt ttttagaatt tataacaata ggttaatata
   119041 tttataatta atgtaaaaat tattcatatc tattaaatca aattcttaca catataatta
   119101 ttggtatgct tattaacact ccagaaactc ttatagttta aaatttaaat ttattgttat
   119161 ttattattta atttgagaac atgatttatt ttttatttaa agctaataag tagagcatga
   119221 ttctacagta taatttctta aatttttttt aaaaagtaat agttcttatt tatagtcaat
   119281 attgcctata gaacttctga ttcatttaat ttttaggaaa aaataataat acttacgcta
   119341 taaacacaga attttagttg ataatatagg tatttaaatt taagatgaaa taatactttt
   119401 ctcaatatat tttattgtaa ctaagtttaa ttataagtta caattaaaaa aacgctactt
   119461 aggaggaatg taattatggg gatgatagga tgttatacta aaataagtga agagaatgtt
   119521 tttaaattac agcaagcaga agaaaattta caagattttg tttttgaaga tgccaacgaa
   119581 aatagtacta tcaatattga taaagcatgg catgccattc actttacttt gacaggttgt
   119641 ccttttggtg gagatgatga taatatattt agcaaattag tactaagtgg aaacatactt
   119701 atggaaattg atggagaatt tcctgtcatg ttgattacag caaatgatgt aaaaaaacta
   119761 tcaaaagcaa tgaacagttt ggaagaacaa gcatttagaa aaagatttaa tattaatgag
   119821 atgttagaaa ataatattta tcctgttatg aatgatgaga gtgaagatga tttttttgaa
   119881 tatgtatggg caaatctaat tgagcttaaa aagtttatac aagaagcatc taatgatgga
   119941 ctagctgtaa tattttttat aatgtgataa ttactaaaaa ttgtgaatat tagtgtcatc
   120001 acatatctta gatatgaagc cttttgattg tatagaagaa atacatatta tattagcctt
   120061 ttaaaatata taagttaaat ttaaatctgt aggtaaattt gtcttatgtc tttataaata
   120121 tttatattag catatataaa ttagttttaa atttttgcaa tatatagttg cagatatttt
   120181 tatttatctt aaaaggctaa ataccctatc ttattatatc cagtaattct tttggatact
   120241 tatcacattt ttcattatat ataaaaatag actcacaaat aaaataaata tatattaaat
   120301 tataacttca taaacttaaa aaatttcaga aacaaagata ctttaattta attaaaaaca
   120361 gaaaaattaa aatctttaga aaaaatttag aaatttataa ataatatctt aagttttaga
   120421 atttattatg aaaatacagt aaaaatttat aaaaataaaa ttctataaaa ttatttctgg
   120481 gggtgtattt atatatggaa atgaaaatag cagtatccaa tcttagtaaa agatttggga
   120541 aaaaacaagc tcttgataat ataaatcttg aaatcgacag tggtatgttt ggtcttttag
   120601 gaagaaatgg agcaggaaaa accacattta tgagaatttt agccacttta ttatcaaaaa
   120661 cagaaggttc aatacatatg tgtggagttc ctattgagaa tactaaggaa attagaaata
   120721 tggttggtta tttgccacaa gatttttcaa tgtatcctaa catgacagta tataaagcaa
   120781 tggattattt agcagtttta tcggatatac cactaagaaa aagaagaaaa attatagcaa
   120841 agttattaag caaagtaaac cttactaatt atcaaaatgt gaaagtaaaa tctttatctg
   120901 gaggtatgaa tagaaggctt gggatagcac aagcattaat tcataatccc agagttttaa
   120961 tagtagatga gccgacagca ggtcttgacc cagaagaacg tataagattt agaaatttac
   121021 tatgcgaaat tgcaaatgat agaatcgtta ttttatctac acatattgtt ggagatatag
   121081 aagctacatg tgaaaacgta gctatattga atagtggaaa agtcatatac aatggctcaa
   121141 cagaagcatt agcaaaacta gctgaaggga aagtatatag tattgaagta gataaaaaag
   121201 acattgaaaa tataaaaagt agatttatag ttataggaat gttgactcat ggtggaaagg
   121261 ctatacttag gattatatca gatgataaac cttttgagac agcagtaaat tgtaatccaa
   121321 ctattgaaga tggctatatg cttataatgg gaggagataa tatatgaatc tatttataaa
   121381 agaatgtaaa aatatattaa agagtatggt atattatatt tttattgtag ttttagtttt
   121441 tttctatatt tctcaacttg gaagttcagt ttcaaatgat gtaagtaaaa atattcctaa
   121501 tgatggaaat ccattagttg ctccacaaaa agtagagaat attgaggaat attattctgt
   121561 acacaatcaa tatccatatg gtcaaaaaga atctatgaaa acagaaaagg tcattccaaa
   121621 tgcaactata aacctaatta gagaatatca aaaaaacaca tatacaacgt atccaacagg
   121681 ggtagttaag tatataaaat tagaccaaaa taaaacgaag accatagaaa aatatataga
   121741 agaaataact ggtaaaagta ttagcgaaat aaattcactt tggaaaactg atgaaagtat
   121801 aaaaatagat tattctaaag tatctcttga aagatttgaa gaaataatgc aaagagtaga
   121861 ccacatttta ggaggagggt ctgcatatgc ttttgacaag ttacaaagat ttggagtagt
   121921 tccagttacc tatgatgaag ctatgaagaa ttacaactat acaatacaaa aagataaagt
   121981 tagtaatggg tatgcaagaa ttttttgcga ttatataggt atagttttaa gtatatttcc
   122041 agtatttgtg gcagttttta tgtcacttaa agataagcgt tcaagaatga gagagattat
   122101 ttattcaaaa caagtatctt catgcaaaat agttttatca agatattttg cacttgtctt
   122161 tatgatgata ttgcctgtat taattttagg tatgaaagat ttacttcctt tgattttctt
   122221 tgctaaagat aaaggtatat ctattgataa cttagcattt ataaaatata cattatggtg
   122281 gatactacca actcttatga tagttacagc tgtaggaatg agtattacta tattaacaga
   122341 tacaccagta gcaattattg tgcaattaat ttggtggctt tacagtataa attctacagg
   122401 actcaaaggt gattattcaa caatgggact aatgataaga cataatagtg tattaaatgg
   122461 agatattatt atacaaaact tcaatcaaat tatgattaat agaattgtga taagcttgga
   122521 agcattggtg cttgttttgt tagctatatt cttatatgag caaaaaagaa gggggaatct
   122581 tgatgtttgg gcaaagtttt caaaactgtt tagttctaat aaaagaaaac ttcaaattaa
   122641 gcactttaac taatttaata tgttcaatta tattgctatg tatgattcct ctaatacaag
   122701 gagtagctaa tttagacaga atttcaacag ctatatgttt agaaaattat gttgcaataa
   122761 tagggatagt aatgttggta cctgtatttt cgctagagca atcaaaagaa attgatgaga
   122821 tagtatcttc aaaagcatta tctcaagtta ttgtacaatt aattaggata ctgatgtcaa
   122881 ttataggtat agtggtatta atcataggtt ttgtaaatgt tttaatatat cttggatgta
   122941 attttccagt agttgagtat attattggaa gtttcgcatc agctatgttt ataggaagtt
   123001 taggaatgtt tttctcaaat ttatttaata atacaatcat aggttatatg atatctatag
   123061 gatatttaat tttaaatatg atgactaaag gcaagtatgt tggaaaattt tttataatgt
   123121 ctatgagtca aggtagtttt gatgagaaat attggctgat acttggaagt gttgtgttga
   123181 taattgcatc tctcttaata aaaccagtaa aaaggaagat tagataataa aatgagagct
   123241 tagataaaat aaagttaata caaataaaag gtacatttat gaaatataaa tctattttta
   123301 tatacacaaa cctacttaca atctctttat gtatgtagat agatttatat atccgtagta
   123361 taaaatatat atgtatacca aattttatca aaagctctca aatttatatt tcaaagacac
   123421 ttattgctat gacctacaca tatgtatttt tttattttaa ttgttgtatt aacaataaga
   123481 ctattgttat aaactattga tacctcataa caaaaaattc tccatctcct aaatgcgttt
   123541 tttgtacctt agtctcaact attttaaatc cttgagactc ataacatttt acagctctca
   123601 tgttccaggt tcttacattt aatacaattg gtttagtact atatttattt ctacattctt
   123661 gtaatcttag gctaattatt tctttaccaa ttcccattcc acaataattc ggtttcatac
   123721 caataccaaa gaatacagag cttccttcat ctaataagtt tataaaacct atcaattctt
   123781 tattgtcatt tataaaactt ataaaatttt ttcttttatc ttcttttgct agtgaaaaat
   123841 tcttcttttt aatttcctcc catggaggta gattgtatat tgaatattta ccttcatatt
   123901 tccaattagt aacttcaata gcatgttctt cagtaaattt aactttattt aaattcatat
   123961 gtcctcctat taaaatattt aaggtaatta atggtatttt aaagttttag acaataagta
   124021 aaactactta tatttatcca taaaatcttt aaaaatttta ctaacaattc ttgtaccctg
   124081 tactttttat tggattcaca gaagactata aactaatttt gaattacctt ctaattcaaa
   124141 aacatcacga tatatataat ttcttagctt gattaaattc tgttaaatcc gtttcttata
   124201 gttgtataat caacatcaat atctttatgt gtattagtta atttattggc tttaggaact
   124261 tattattaat atattgtatt tactccaagt agtaggtaaa ttataggcaa attatcaaat
   124321 gtatatctat ccatgcttaa actttagaga tacaataact actaaattac tattctagta
   124381 gttataaaaa agaatcttta aaaatattaa tttaacttat attttttaat aaattttcta
   124441 aaatttaata agttaattta attatagctc taaatgatat tttctacaga tataatttta
   124501 aaaagatgtg tataagaaca aattcactta aatttttaaa atcaaataaa gttgaatctc
   124561 ttgactacct tgattgtttt atgaaattaa tatagatgta aactttttaa tatagatgta
   124621 aactttacta ttaaaaaaat acaagatttt agataagtta atgctaatta taaataataa
   124681 gataagaaat ataatatgac ataagggcta ggaataagat aaatataatc aaagaataag
   124741 atatgagaat aattactaag agaaatcatt accttaatat gtttataaat gttagactat
   124801 gttcctaaat tgaattttat atatcaagta taataacctt acagaatgtg gaaattttta
   124861 tttaaagaat acacataaac atttccacac tctgatttta taataataat ctaataaaat
   124921 ttatagtgac tttataaaat caataatgat ttaataaata tttataaaac aactattttt
   124981 gcttagaaac tttattattc atattatcat tagtaggcat tgctccaaaa cttagttttt
   125041 catacattac ttgagttgga gctagccaaa ctgtaccact accagtaaat gtatttaaga
   125101 aaccttcacc atttaaagca gaaccaatta aagatttatc tgattttgta acagaaaaat
   125161 taacaccaga tgttcttgct attgcaaagt taccatctac ctttaattct tcaccatttt
   125221 tcaattcata ctctacaatt tcactttgag gtacaacaca ttccagaacg attacaccag
   125281 taccacttaa ttctatttgg aagaagcctt caccaccaag taaagcagat gagaagttct
   125341 tttgtgtaaa tgcttttact tctattgtat cagagcaaca atagaataat cctttatcaa
   125401 caattataga atcattatca agactcataa ataaataatg tctaaaagaa ggttccaaat
   125461 aaacttctcc agtacctttg tatacaggtt tcatcattga ttcattagta agtgctcctg
   125521 atattccttt tttaaaaaga cctccaacac caccaatctt agtttcagaa gatatatttc
   125581 ctttataata gtataatgca ccagcttctg tttttattga tgaattattt aattttatct
   125641 taatttgtct agctttcaaa ccagcttctc tagcaaaata taatcccatt gccattaatg
   125701 ggctagaagc tccctcaagt ttttcaaatt ctaatatctc aaattcgctt tttccatctg
   125761 atgcattttc taaaattttt acttttttgc ttaaatccat acaaatttct ccccactatg
   125821 ataaaattta tctctaaaat attataagat ataactctat attacatttt ttttgaaaaa
   125881 atcgctactt tatcatcaaa tttttacata tttttaagaa gtttttgaaa tgtttagatt
   125941 taagttaagt tatttaagga tgtatagtta tttcaataga cattttgagt attatttatc
   126001 atttgtgggt attatatttt atgggcatgt taaaattat
//
LOCUS       DAFAZV010000008       124094 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFAZV010000008 DAFAZV010000000
VERSION     DAFAZV010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 124094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 124094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..124094
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.008"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(302..1183)
                     /locus_tag="KOU88_000893"
     CDS             complement(302..1183)
                     /locus_tag="KOU88_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline iminopeptidase-family hydrolase"
                     /protein_id="HBK3210801.1"
                     /translation="MKITEGYMPFKGFKTYYRIVGENTEGKKPLVLLHGGPGSTHNYF
                     EVLDKIAESGRQVIMYDQIGCGNSFVEGHPELFNADTWIEELIELRKHLGLDEIHLLG
                     QSWGGMQAIWYAIEYKPKGIKSYILSSTLSSAKLWEKEQKRRISYMSEADQKALLDAV
                     NTGDYSSKEYNDALERFMEMYCAGEVTEDSPECLRRPKKSGSEAYIVGWGQNEFSPTG
                     TLSGYEFTDRLHEIKEPCLVTSGAIDLCSPYIAKTMYDRIPNSKWELFEYSRHMPFVE
                     ENEKYIKVLTEWLNEND"
     gene            1639..2613
                     /locus_tag="KOU88_000894"
     CDS             1639..2613
                     /locus_tag="KOU88_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210802.1"
                     /translation="MNNINSLKVIKLSLGCSLAIFIAWLLKLEYSMVAGVIVLLTVKD
                     TKRETLKGSIGKIYGFLLCTIFSYLCFNILGYNLTSFSIFIFIIIPLCFLLNIQDVIA
                     MCVVIASHYYLQGETSIKWILNEAGIFAVGTGIGVLINMYIPTNIHKIHEVQKKLQEE
                     VSIVLIDIADIIVNPKKENGYSRDLYTLNSLIDSSISETYDNINNTLLSDTRFFLEHM
                     DIIKSQRDILENLYSYVSQLNSTPPQAHILSAFIHKIGYTEFEAETGNLLLEELKRLM
                     LSMKNQPLPVDRTEFENRAILFLCLTELKQFLVNRKHAQMLRDNNFYK"
     gene            complement(2729..3790)
                     /locus_tag="KOU88_000895"
     CDS             complement(2729..3790)
                     /locus_tag="KOU88_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
                     /protein_id="HBK3210803.1"
                     /translation="MKKIRKLATKLLITTIVLISGMSMTVYGMTAKEVTAKTPKSYVT
                     GTNSVYGPKLSQAQLNSVAQATADFMNKKITKNMTTDAKILVAYNHIKNNTTYVDWNA
                     VEGANTAYTLVTKKGACSGMARSMKALCDAMGIESYYVHSTSNDHQWNLIRFGDGRLY
                     HVDIDANKSAGKDIIYKSLSHPLPFDKTAYPKVGAIVQTVKPEQTQKPAPPGKHTMLP
                     HQEGAKAVGNFGKKGEDINEKHVMYEGVRCSVVNSSVNTITFTGSESNLDPSNLTIAV
                     IGFMNTPYGMFALAPEGKPVEYPFKYDKPFSLDFSGKNRSGAELAKYCKKNDVTIKIE
                     ITDEKANIGLGQIMYVRYE"
     gene            complement(4401..5252)
                     /locus_tag="KOU88_000896"
     CDS             complement(4401..5252)
                     /locus_tag="KOU88_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3210804.1"
                     /translation="MSCILKLKQIYEDLTEVDKKIADYILNNTEAISKLSVSELASNS
                     KTSTASIVRFSRKMGYSGFGDLKIEIAKDLMGKENEYTYVDENYDCNIDSVINKITNK
                     NIETINQTRLLNEKDIIKEAVEQIIKAKNVYIFGVGGSALVALDLQMKLLRINKQAFT
                     SLDSHTQLMVSSNVDKEDIAIAISYSGESKEVIKSIENAKLKGCKVICITKYSDNHLS
                     KISDLKLVVPNIEKRLREGAISSRIAMLTLIDIIYISIIQENLNEAEQKLQETKRILD
                     YLNINNA"
     gene            complement(5269..6189)
                     /locus_tag="KOU88_000897"
     CDS             complement(5269..6189)
                     /locus_tag="KOU88_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA reductase"
                     /protein_id="HBK3210805.1"
                     /translation="MYFLGVDGGGTKTTFTLVDEELNIVGTITKGTCHYNQIGFDNLT
                     KLLITGLEEVCKDAKINVEEITYAFVGLAGYGKIKEVLYALEVATKNAYSHINYTLGN
                     DVEIALAGSLNGEKGINIIAGTGSIAQALDKDGNLHRCGGWGYVLGDEGSAYYIGMAT
                     LKMFTMQSDGRCSKTKLYDLIKRHLNIENDYDIIKYVNDEIQGDRIEIAKFATICLKA
                     VIEGDNTASKIFDDAAYELSRLIIGLEHHFEQGTKIKVSYSGGVFKSGDLILEPLKKY
                     LNKTRFGIVRPVLTPDLGACLLAKKKYYSK"
     gene            complement(6299..7213)
                     /gene="murQ"
                     /locus_tag="KOU88_000898"
     CDS             complement(6299..7213)
                     /gene="murQ"
                     /locus_tag="KOU88_000898"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBK3210806.1"
                     /translation="MLIKTLENLVTEGRNKNTLQIDKEDTLGIIELINNEDKTVAYAV
                     EEQKESIAKAVNIIVDRMKQGGRLFYIGAGTSGRIGILDATECPPTYGVDFELVQAII
                     AGGNQAIFKAIEGAEDDKELGKQDIIDRGVTSKDVICGIAASGRTPYVIGAMEYAKEL
                     GCAVLSITMNPNSEMSKKADLPINIIVGAEVIMGSTRMKSGTAQKMVCNMLTTASMVK
                     MGKVYSNLMVDVKTSNEKLVERAKRIIMIATNVKYDVAEKFLEEADNSVKLAIFMIKS
                     GLDKDSAKSILDRQEGYISEALKSIEKL"
     gene            complement(7312..8409)
                     /locus_tag="KOU88_000899"
     CDS             complement(7312..8409)
                     /locus_tag="KOU88_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBK3210807.1"
                     /translation="MGRLGISIYPEKTTSKEIYDYIDKAAENGFTRIFSCLLSVKDTK
                     ENIIKKFKSINEYAKFKGFEVILDVNPRVFGELEISYKDLNFFKKTKADGIRLDMGFT
                     GSEEALMTFNPQNLKIEINMSNNTNYIDTIMDYQPNKENLIGCHNFYPHRYSGLNLEH
                     FIKCTERFNKYGLRTAVFVTSQNETTFGPWPVTDGLPTIEMHRNLPIDIQVKHIIAMN
                     NINDIIISNCYPTYEELKVLGSMRKDMVTFDVAIEENIREVEKKILFEEIHFNRGDIS
                     DSLIRSTQSRVKYKGYKFELFNTPKIIKRGDIVIESSEYGHYAGELQIALTDMKNSGK
                     SNVVGYIRKEELFILDYIKPWQKFNFKPSTK"
     gene            complement(8642..9988)
                     /locus_tag="KOU88_000900"
     CDS             complement(8642..9988)
                     /locus_tag="KOU88_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3210808.1"
                     /translation="MLDKFTEFLDTKLSTSMARLAEQRHLRAVRDGIVASLPLIIVGS
                     FFLILAFPPLPDSWGVTQYLKENAVTILLPYRMTFFIISVYSTFGIGYSLAKSYKLDG
                     LTGGLLATATFLLTIVPTAIEGLTPDLLKIVEKSPELLAWYNSIPQGWQMPMANLGGG
                     SMFVAIVTSIIGVEIYRFTDKSKFKITMPEAVPASVTRSFEALTPAALIIILMAIVTY
                     FLGFDWHGFIAKLVTPLVSATDTLPSVIILIFLITFFWSFGIHGVSIIGSLARPLWIQ
                     LLDANTASYAAGQAVPGIAAEPFFQWFIWIGGSGATIGLALLLAFRAKSAYGKSLGKA
                     TVIPAIFNINEPIIFGAPIVLNPILIIPFVVAPIVMATVSWFAMSANLVSRVVVTAPW
                     TLPGPVGAYLATGGDWRASVLNLLCIAISIIIYYPFVKMYDKRLLHEEKVEEQEAY"
     gene            complement(10077..10385)
                     /locus_tag="KOU88_000901"
     CDS             complement(10077..10385)
                     /locus_tag="KOU88_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210809.1"
                     /translation="MRVLFVCSSGMSSAIAVNALQKEGAKNGIDIDVLAVGTQEFEDE
                     VKNGWDIAMVAPQVRHRFDYLKAFADEVSVPCALIQAQAYSPLGGPKLLKQVQELLSK
                     "
     gene            complement(10646..11044)
                     /locus_tag="KOU88_000902"
     CDS             complement(10646..11044)
                     /locus_tag="KOU88_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210810.1"
                     /translation="MSNNKKKKRKKNNNYKNAKSTKSNKNTKKQMEKNQRTDYNIPTI
                     SFKSGLILIVSSLVSTVVFPLLLSIFGIDNRFGVVIGNSLITSFAVAYTRYFVETKRG
                     FSLGFFRLYILFALSFAIIGYFWIYKGIHI"
     gene            complement(11046..12206)
                     /locus_tag="KOU88_000903"
     CDS             complement(11046..12206)
                     /locus_tag="KOU88_000903"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBK3210811.1"
                     /translation="MITMYSVGLMSGTSLDGVDAVLAEISGNGRNTKVKQIEFITLEI
                     PKDIKDEIRKCCIEEESSVDLICSLNFKLGYLFSKAVKSVCHKANFHIANLDFIASHG
                     QTIFHIPRSYNNFVSSTLQIGEPAVIAYETNTKVISNFRVMDIAAGGEGAPLVPYSEF
                     LLYSDNNKNLALQNIGGIGNITIIPKSCNIDDVFAFDTGPGNMIIDGVCQRLFNRKYD
                     KNGYFASKGKINEEMLKDLMSHKYLSQAPPKSTGREVFGQVYLDNMLNKYKHVDKYDL
                     IATVTMFTAKAIYYNYKNFILSKVNVDTLLIGGGGAHNLTLIGYIKELLLEVEVLTQD
                     EYGYSSDAKEALAFVILGNETLNNSFSNVISATGAKNKVILGNITPKPFGGK"
     gene            complement(12637..13656)
                     /locus_tag="KOU88_000904"
     CDS             complement(12637..13656)
                     /locus_tag="KOU88_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3210812.1"
                     /translation="MLVKYLKGRSKYIALPLVVVSIINIYLFAIDIFKNKYSELIYLD
                     FLVLFIIMVFFVIDYINFRNSYTNLYNCIENSGEIDSYLVNGQSFEENLIKDIIENLK
                     IKNNSDIETYKQSLKELDEYIAKWVHEIKIPISSLSIITDRLSSIEDSLDIKNQVAKI
                     NFLVNSILYSSRSNTMFEDVFINKFNLEKLVKMSIKNNSFLLIKNNVEVSLNELENDV
                     YTDSKCMSYVLDQIINNAIKYSKEVGKIEFNSKKLENGVVLSIKDFGIGINEEDISRV
                     FDKGFTGKNGRNQLYKSTGMGMYFVKKMIDSLGHEIEVCSKIGSYTIFNIYFYDISDY
                     LSLDS"
     gene            complement(13650..14330)
                     /locus_tag="KOU88_000905"
     CDS             complement(13650..14330)
                     /locus_tag="KOU88_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210813.1"
                     /translation="MYRILLVEDDIDLSKEIALALEKWGFKVELIDDFEVVLDEFIDK
                     KPDVVLLDVNLPLYNGFYWCEKIRAISNVPLIFLSSRDSDMDLIMGINNGADDYITKP
                     FSIEILVTKINGIIRRVYNYSDSNSILYCEDLMFDVGKGIIKHKYKDKSIELTKNEIK
                     ILTLLLKNKNRVVSRESLMMTLWDNDEFVTDNALTVNMNRLRSKVKELGFDDFIKTKK
                     GIGYIIQC"
     gene            complement(14482..16389)
                     /locus_tag="KOU88_000906"
     CDS             complement(14482..16389)
                     /locus_tag="KOU88_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBK3210814.1"
                     /translation="MSILGIAYNNFKSNIRTYLAFFISMVFSVVVLTNFELLRYGDAI
                     NMLQEENKKFTLSVLVAVIMILSVFLFFFIWYATNIFFKNRSKEIGILSFMGLDLYTI
                     GKIYFVENMLIGISSCITGIIIGIITSRFFQVMIIKLSGFNIKVSNGLSIEAILYATL
                     IFISIFIIMAVKGFITICRSSVINLINISKKQEKIPKVGIGIYILAIISITVIGYGYY
                     LSTNIRTGNITSVLPVIGIIIVGTYGLFKSVMPVIFDIIIKNKKILFNGNNIIAINNI
                     NYRLNKNYKTYAIIAIIITTTISTLGASVAMKRIHKNAQEQRNVYTISIVSMDKDEVN
                     KKQIENIIKDTNKIKYSVNPELTILKKTDIKEAYDTTDTIMKYSDFCNTLKVNGNDKE
                     LKEYDERLVSGNNVIDLKSPQTIASIATKEAKIKLDGQLYNISRGEVKVPVLGTGLNQ
                     SIIVVNDDTYFKLRDKGQQVYFYGAKVFQEENSQVMFNNIEKNLSLKNGYIQNGYKAQ
                     GESQWMKFAYVVLVFLFLVFAIVAGSIIYMKIYSDAYEDKEKYKILLKIGTTEKDINR
                     AILKEVAIFYTLPMLSATISSYFALRLAGDLLMTDLFGIYILSLVICLIIFIIYGAVS
                     VNKFKSVVYKN"
     gene            complement(16390..17142)
                     /locus_tag="KOU88_000907"
     CDS             complement(16390..17142)
                     /locus_tag="KOU88_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210815.1"
                     /translation="MKEILKIKNISKDYGIKGFKTNVLKNISLTVNEGDFIAIMGPSG
                     AGKTTLLNLMSTLDKQTSGEIILDGINISKVKNNELSKLRREKIGFIFQDYNLLDNMK
                     LMDNIALPLALGKKKSKEIEAKVFSIAKKFGLENHLDKYPYQLSGGQKQRGAAARSLI
                     TNPTVIFADEPTGALDSKSAYELLESLEKINRENNATIIMITHDPLTASYSNEVYMIN
                     DGNIKCKLNKGNSRKEFYGKIMDMLASMGGEM"
     gene            complement(17462..18613)
                     /locus_tag="KOU88_000908"
     CDS             complement(17462..18613)
                     /locus_tag="KOU88_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3210816.1"
                     /translation="MINKAIKFKFIIFYFFSYIIFAFASTKFTPFLSKLGYSAFERGI
                     ILSSYAITNILFQLLFGVLADKYQTMKKIVLISLSVYGIASVIMFSTESATFIIYLLL
                     VALSGGLLNTCCSLYDTWIIGCGDNINNYLSFIKTFGSIGWAIGSMVASYLILRFSYF
                     GLSVAIGLIVVLLIINLLLLPDIEKINKKINVTNKDIIELLKDKKYILLVCILFLLYS
                     MVVANNCTVIDKMIALNATNSQISLKWSLQSLLEIPTYLAGSYLLKKYSSLNLLKLSA
                     IMITVQFLLFALTNDSNIIIILCVFQVFSTPLILITSKRLIFEVSPKKLRSSSQLIAL
                     SIFMGGSSLIIPTVAGFLSINIGYNYTLMVLSLFGCLAYGLIVLLNYLQ"
     gene            complement(18616..19083)
                     /locus_tag="KOU88_000909"
     CDS             complement(18616..19083)
                     /locus_tag="KOU88_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3210817.1"
                     /translation="MFFKRKKEAITINSYIDGKIINLGEIPDKVFSTKVMGDGFAMIA
                     KDNILKSPTKGVISFIAQTNHAIGIKLQNDVQILIHIGLDSATTKKENFKLEVKQGQE
                     VNMGEKLVEIDNKLLENTLYIPLVIVENPNTVKYHLSNLNQEGNSGIKVINFD"
     gene            complement(19097..19585)
                     /locus_tag="KOU88_000910"
     CDS             complement(19097..19585)
                     /locus_tag="KOU88_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210818.1"
                     /translation="MITNKIKNITAVLKDENIFLSVVMVCFLILPVLYIVYLELTSLF
                     TNISFSQLLNNDVNASLNLISNFSAVYSAYVIYNIKKNKEIKENMIAFYLVLLGQIFQ
                     IYTITIVIMFTYIYKFVGIRQIISSIKELQWGKSYKALFSSIAVCLISLFVMIIRIKL
                     IM"
     gene            complement(19599..20930)
                     /locus_tag="KOU88_000911"
     CDS             complement(19599..20930)
                     /locus_tag="KOU88_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBK3210819.1"
                     /translation="MERKRQRILIAGGGSTYTAGIVTMLIESVAKFPIESIKLYDNND
                     ERQRKVAEACAIIVREKNPEIKFSYTTNPEEAFTDIDFVMAQIRVGLYALREQDEKIP
                     LKYGVVGQETCGAGGIAYGLRTIGPIIEMIDYMEKYSPNAWMLNYSNPAAIVAEACRV
                     LRPNSRIINICDMPVCLEEIFARVLGLNSRKDFDVRYYGLNHFGWWTSIKDKEGNDLM
                     PKLQEYCAKKGYEEFTPQGQHKESSWLETMRAAKDLLEIEPTTLPNTYLKYYLMADET
                     VEHANPNYTRANEIMDRREKDTFEECERIIKNGTARDTWFDASEHSQFIVELACALAF
                     NTQERFLLIVPNNGAIENFADDAMVEIPCLVGKDMVEPMSIGKIPTFQKGLMEQQVAS
                     EKLAVEAWIEKSYQKLWQSFTMSKTVPSAKVAKEILDEMIVANKDFWPTFK"
     gene            complement(20944..22509)
                     /locus_tag="KOU88_000912"
     CDS             complement(20944..22509)
                     /locus_tag="KOU88_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003233606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK3210820.1"
                     /translation="MMKKIQRFGGAMFTPTLLFAFAGIMVGFSIVFQNQSIMGSLATP
                     ENIWYQFWGVISSGAWMVFNQLPLLFAISLPIALAKKQQARACMEALATYLTFNYFVG
                     SMLSFWGKSFGVDFAAEISAGSGLVSIAGIKTLDTGMVGALLISGIVIYIHNRFYDKE
                     LPDFIGLFRGSSLVVAICFFVMIPVALLTCFIWPHIQNVIRHLQTFFINSGNIGVWCY
                     AFLQKILIPTGLHHFVYAPICYDSVVVPGGTSVYWATHIQDFQTSAKTLKEMYPIGFS
                     LSGLSKVFGSLGVFGAFYVTAKPEKKKKVLGLMIPATLTAVLTGITEPLEFTFLFVAP
                     LLFLVHAFLDACLQTISFALGVVGDFGGGIINWVVLNWLPLGMYHWKVYVVQVVVGII
                     FSFIWFFVFTFLIKKFDMKTPGREEDSEETKLYTKNEYLETKDEKGNKLSKASQQASE
                     YIKLVGGAENVVDVTNCATRLRLTLKDDSIISKEEDFKAVGAHGLVHNGKAIQIIIGL
                     SVPSVREEFENLL"
     gene            complement(22678..23463)
                     /locus_tag="KOU88_000913"
     CDS             complement(22678..23463)
                     /locus_tag="KOU88_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3210821.1"
                     /translation="MRLEEMIFLNYNKLNDTDLLIWKYITANKKHCSKMSINELAMKC
                     NVSRATITRFVKKLDLKGFSEFKVLLSWESEKVHVIENQSFDIACNSIIKYVEDQKNK
                     DYDALCKLLYESRTIYAYGSGDIQNVVAKQIKRMFLSCQEIIYDFEGRTFDDSFYNIV
                     SKNDVMIIISLSGENENTLNIARRLKLIGTKIISITEFKNNTLTDLSDESIYISATNI
                     SFLQMHPSYKLTMLYFILIELLFIKYSIYKRHRMITEGIDCKL"
     gene            complement(23630..24829)
                     /locus_tag="KOU88_000914"
     CDS             complement(23630..24829)
                     /locus_tag="KOU88_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S41"
                     /protein_id="HBK3210822.1"
                     /translation="MKKKVLFLVIILAFIILLGNSTYSQKNQLSEEEKVDDFNYVYNV
                     VKTGYPYLGVNKRLNNIDWLANKDEYTKRIKNTENDEEFIEELSSILSDLNNKHTEVI
                     DNKKRYELFKKSYSNNGWYDFLNDKKVVDRYDSMNLKIKMPDDIFVKKELILKDVIKG
                     QIGYMYLPSMSSKNGSINNDLKIIGDYINTLEKHKALIIDIRGNLGGSDSYWQGIVSK
                     LIKNDVKINGYRIYRNNNEIVKKYTNARNIKLNPVENLPASVKENAPKEIIKDFNDFE
                     DTSYTIKSTDDSKFKGNIYLLVDRKIYSSSESFAMFCKENKFATLVGETTGGDGGCID
                     PVLFNLKNSGLIVRMASCMYLNKNGICDEEFKTIPEFKVKDCKRTADFKDDNCIRKAL
                     ELENINY"
     gene            complement(25351..26688)
                     /gene="xylA"
                     /locus_tag="KOU88_000915"
     CDS             complement(25351..26688)
                     /gene="xylA"
                     /locus_tag="KOU88_000915"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBK3210823.1"
                     /translation="MSEIFKGIGQIKFEGVKSDNELAFRYYNPEQVVGNKTMKEHLRF
                     AMSYWHTLCGEGNDPFGVGTVERPWNNITDPIEIAKIKVDAGFEFMSKMGIEYFCFHD
                     RDIAPEGRDLEETNKILDEIVEYIKVNMEKTGIKLLWGTANMFGNPRFVHGASTTCNA
                     DVYAYAAAQVKKAMEITKYLGGENFVFWGGREGYETLLNTNTELEMDNFARFLQMAVD
                     YAKEIGFTGQFLIEPKPKEPTKHQYDFDTATVLGFLRKYNLDKYFKMNIEANHATLAG
                     HTFQHELNISRINNVLGSIDANQGDLLLGWDTDQFPTNIYDATLAMYEVLKQGGIAPG
                     GFNFDSKVRRASFEVEDLFLAYIAGMDTFAKGLLIAHKLLEDEVFENFTKERYASFSE
                     GIGKDIVEGKVGFKELESYALQMPVIKNKSGRQEMLEAILNRYIYEVDTISNK"
     gene            complement(26784..28334)
                     /gene="xylB"
                     /locus_tag="KOU88_000916"
     CDS             complement(26784..28334)
                     /gene="xylB"
                     /locus_tag="KOU88_000916"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBK3210824.1"
                     /translation="MKLEYVLGVDIGTSGTKTVLFDKLGNTIKSCTYEYPLIQEKSGW
                     AEQDANDWWKAVVESIREVVQSSNISSECIKGIGLSGQMHGLVMLDNEGKTLRNSIIW
                     CDQRTVKECEEITDLVGEERLIEITANPALTGFTASKILWVRNNEPDIYKNTNKILLP
                     KDYIRYKLTGEYATEVSDASGMQLLDIRKRDWSDEVLEKLNIDKNLLGKVYESQEITG
                     YVTRDVASLTGLKEGTIVVGGAGDQAAGAIGNGIVKDGVVSSTIGTSGVVFAYTKEPK
                     IDKEGRVHTFCHAIPNTWHVMGVTQGAGLSLKWFKDNFCQSEVEVSNSLGEDVYEIIN
                     NQVSQVPTGCNGLLYLPYMMGERTPHLDPYARGVFFGLSPIHSKKEIARSIMEGVSYS
                     LKDCMDIIENLNIDVNEVRASGGGGKSKVWRQMQADMFNQDVYTINSSEGPALGVAIL
                     ALVGAGIYENIQKACDAIIKTSTKLEPISENVDTYNIYHRLYKRIYKSLKDDFKLLDE
                     VVNAKINN"
     gene            28542..29702
                     /locus_tag="KOU88_000917"
     CDS             28542..29702
                     /locus_tag="KOU88_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBK3210825.1"
                     /translation="MVTDKYTIREMNERLVLEQIIKNGPISRASIASTIGLNKATISA
                     ITKKLIDESLVHEIGIGNSTHSGGRKPILLVFNKCAGISLSMDIGYDYIFSSLSYLDG
                     TIINSKKLTDIQVSKDNVIQLIDEIINSYNISKIDTPYKVIGLTLAIHGITCENKVLF
                     TPYYNLNEIDLYSILSKKYDFPIHIENEANLTALAENTFSTVHNSLLSLSIHSGFGSG
                     IIINNKLYSGRNGMSGEIGHTIIMPNGKLCPCGNRGCLEQYCSEKKVFEQLSSLENIP
                     KIDSDIVKQLYYEDNQNAKKVIHEFCSYLTIAINNAITTYAPEIIYLNSQIISDIPEI
                     LQITKDMLVSSFNKGINIEISSLGSEASLYGGSAVNIKSFLNIQNLTLINEI"
     gene            complement(29858..30262)
                     /locus_tag="KOU88_000918"
     CDS             complement(29858..30262)
                     /locus_tag="KOU88_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3210826.1"
                     /translation="MNSIILMSHGNMAEEVLNSAKMIIGDSIDYPTVNMKQDDGIEGT
                     IEKLKKALEVYKESSEIIIMADLLGGTPCNAALLVANNDSRIKIISGLNLGMVIESAF
                     LDTKELAAKLEKIGKDNISMVEQNASLLSDDE"
     gene            complement(30283..30765)
                     /locus_tag="KOU88_000919"
     CDS             complement(30283..30765)
                     /locus_tag="KOU88_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210827.1"
                     /translation="MEMKGIKNIRIDDRLIHGQVATMWSNKLGVTRLMVVNDAVANNS
                     VQKQVLRMATPAGIASSIITEETAIKNITAGKYEGQNVLLIVKSPVDLIPFVEAGFKI
                     HNINVGNMSSRKDTTVLRPNISVTEEEKEAFKRLLDEGIEITTIMTPDDKKTYLVDIL
                     "
     gene            complement(30785..31594)
                     /locus_tag="KOU88_000920"
     CDS             complement(30785..31594)
                     /locus_tag="KOU88_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK3210828.1"
                     /translation="MSDKVSLNKSNEKVKKSVLWRWFFTSSVSSNYEKMQALAYCYAV
                     LPFLKVVYKDNPEKLQSAVLNHLQFFNTNPWVAPYILGINVAMEELSSEETEEAVASI
                     KTGLMGPVAGLGDSLFVVIPWTIFGAIAANMAIDGSPFGILLWIVVSVALKLLSIPLF
                     NAGYTSGTKLISSIEKSLKILTESTSILGLMVVGALIPSVVKANVALNFQQGDFTMKG
                     QEILDQIMPGLVPAILVVIVYWALKKNIKPIYLILGVMVVSIILYALGILK"
     gene            complement(31587..32366)
                     /locus_tag="KOU88_000921"
     CDS             complement(31587..32366)
                     /locus_tag="KOU88_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3210829.1"
                     /translation="MEPQLWQLLLIVLYGFFINYEKNSTMFGTYQPVTAGFITGLILG
                     DINTGLYIGGTLQLLSLGISNFGGASIPDYQTASIVATFITITTKQEASVGISIGIPV
                     ALLMVQLDVLRNTIGIWLVHKAEDGAKKGNYKNITYMQMLGVLLTAATTGIPVALSVI
                     FGPSLINTILKYTPEWLTGGLTVAGGLLPAVGIGLLLRYLPAKEYFSYLVIGFVLAVY
                     MKVPLLGVALIGGAIALIIYKKNLENQEQQYTVVGGMDEDE"
     gene            complement(32366..34444)
                     /locus_tag="KOU88_000922"
     CDS             complement(32366..34444)
                     /locus_tag="KOU88_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBK3210830.1"
                     /translation="MIKISEDYIEKRFDNELLRIEAWGKNSLRIRSFVDQNFVDENYA
                     LNEKPKLNKDDITINKNEDGSAIIKNGKIKAVLDHRDRITFYNDKNEILLKEYIRLRA
                     VKHDDGGEDVGTIEITKDFNSTLKLKSREYRPSYSGEFEVTTRFESEPSEKIFGMGQY
                     QHKFLDLKNTVLELAQRNSQISVPFYISSLGYGLLWNNPGIGKVSFAKNMTEWKMFST
                     NFIDYWITCGESPKELNKNYSQVTGTVPMMPENLLGLWQSKLRYRTSEEVLDVVKEYS
                     KRGIKLSSIAIDYFHWPKQGEYKFDLDYWKNPKELVKKLKEEYSVEPIVSVWPTVQSD
                     AENYNDYLENGYLVNVNRGVRMTMQIQGNTVFVDMTNENAREYVWDRIDKNYKQLGID
                     YYWLDVAEPGYSVYDFDNYRYKKGNVLSCGNIYPIDYLKMIYDGLHNDIESVVTLVRG
                     AWAGAQKYGALVWSGDIDSSFEAFNNQVNTGLNMGLAGIPWWTTDIGGFHGGNPKDPE
                     FRELMVRWFQYATFSPILRMHGDRLPHSKPLSNKGGGSMVTGAPNEIWSYGEEVEVIL
                     TKFIKIRESLKTYLKKLMKEAHEDGTPVMRTLFYEFPEDDKTWEVDNTYMLGDEILVA
                     PIMNYKDRSRKVYLPKGHTWENIFSGVSYEGGKTYEVECPLEEIPIFLKQDSSYNFKE
                     LKNILGEVKS"
     gene            complement(35244..35765)
                     /locus_tag="KOU88_000923"
     CDS             complement(35244..35765)
                     /locus_tag="KOU88_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBK3210831.1"
                     /translation="MKRNREIVVVCHCILNCNSKVEGLSEFKGAQNIAINLINKGYGI
                     IQLPCPEMIMYGINRWGHVKEQFDNLFFREQCRQMLIPHVRQFDEYLKNDYDIKSIIA
                     IDGSPSCGYNKTCSSKRWFGELSGCNELMDKIKDIQMVDGKGIFIEELEKLLKEYNLN
                     IPIVGFDELREDK"
     gene            35931..36497
                     /locus_tag="KOU88_000924"
     CDS             35931..36497
                     /locus_tag="KOU88_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK3210832.1"
                     /translation="MDTKKVTFSSMCIVINIVLGMVISMINIPLLFLDTVGTVLGAVV
                     LGPFWGALIGGCTNLVLGVISGPTNIPFALVNIVLGLIVGYISKKKGFGYKEAIITGV
                     ILSIVCPLIGTPISVLLFGGLSGSGADLLVGFLVQSGQKIFTAAFFPRILSNIVDKPL
                     SCIMVVYFISKMPKGFIKQYSKNTSSSY"
     gene            complement(36714..38766)
                     /locus_tag="KOU88_000925"
                     /pseudo
     CDS             complement(36714..38766)
                     /locus_tag="KOU88_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439939.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
     gene            complement(39147..42482)
                     /locus_tag="KOU88_000926"
     CDS             complement(39147..42482)
                     /locus_tag="KOU88_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBK3210833.1"
                     /translation="MGNFDFLQKKKNFNSFNTACLEAEKSILVSPSTCATITRRALEL
                     AVKWLYTNDSDLLLPYQDNLSTLIHNNSFIELIDYDMLPLLKYIVKLGNLSVHTSANI
                     ERGEAILSLNNLHQFVSWIDYCYSDEYTAEDFNEDLLLHGEEKRTRPDELKNLYERLS
                     SKDKKLEEVIKENEELRKSLTEKRKVNTANYDFKIDEVSEFETRKRYINIELKLAGWE
                     FGKDIWEEIEVQGMPNESGVGYVDYVLYGENGKPLAVVEAKRTSKDPKIGQQQAKLYA
                     DCLEKRYSQRPVIFLTNGFDMYIWDDYSDRKVYGFYKKSELQLMIDRRKSKKSLTSVT
                     INDEISNRYYQKEAIRAVCEALENKQRKTLLVCATGTGKTRIAISIVDVLSRHNWIKN
                     ILFLADRKALVKQAKKSFTKLLPNLALCNLLDSKDSPEDARMIFSTYPTMMNAIDDTK
                     SKDGKRLFTPGHFDLIIIDESHRSIYKKYKSIFDYFDSYLMGLTATPKDEIDKNTYSV
                     FDMENGVPTYAYEYNKAVEDGYLVDYTSIEFKTKIMEDGIKYDELSDEEKEEYENTFN
                     DDESIGDEIGNNAVNEWLFNSDTIDLVLNKLMTEGLKIEGEEKIGKTIIFAKNTKHAR
                     AIVERFNKLYPKYGGNFVKAVDYSINYVDSIIDDFSDKNKLPQIAVSVDMLDTGIDIP
                     EILNLVFFKKVRSKTKFWQMIGRGTRLCPDLLGVDMDKERFLIFDFCNNFEFFKFNPK
                     GFEGNKTETLTEKLFNIKVSMVKELQDIKYIEGEYAELRKELLEELITSVKALNEDSY
                     IVRMNLSYVHKYKNENVWSNIGAVAQNEIREYISPLITSYSDDELAKRFDVVMYNIQL
                     AYLQNNNASKGIRHVMATAEKLSKLGTIPQIQQQKYTIEKAMTEDFWEDSDIFEVEEV
                     RISLRELIKYLEKSSQKIYYTSFEDMIVAEDRNDSVYNANNLKNYKKKVEYYLNSHKD
                     ELAIFKLRNNKKITKQDVETLEEILLKQLGNCDDYKKEFGDTPVSQLVRKLVGLDREA
                     ANEAFSEFLNNKSFNTKQIHFVKLIVDYVVKNGFIEDNKVLMEDPFRTVGSIIDLFEN
                     HIEERNKLIKTINKIKENASEIG"
     gene            complement(42532..42960)
                     /locus_tag="KOU88_000927"
     CDS             complement(42532..42960)
                     /locus_tag="KOU88_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210834.1"
                     /translation="MVIRNKLSWNSIEEVNRDFGSCLYDLQNFKILYDKEEMPELWAR
                     YIKEGFKSYMVSFLELTKAMLYYKSIDLNIKSKNFYDHLLTCEYHNLLPKNSSIVIET
                     LRKLRNDDSHGYDIPQFEDMYELFTENEEVFVSIRNSCKK"
     gene            complement(42950..43330)
                     /locus_tag="KOU88_000928"
     CDS             complement(42950..43330)
                     /locus_tag="KOU88_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBK3210835.1"
                     /translation="MRNIPNEIKNSIINVFPKENTLAIIIFGSYGTDKHTSESDIDIA
                     WIPIKKVPITELATKTKALRNILDIDVDLKIVTDNYTIALKKAILEGEVIYESKDFKD
                     YINKFYFENSDVIDILDWRDMYGN"
     gene            complement(43363..43671)
                     /locus_tag="KOU88_000929"
     CDS             complement(43363..43671)
                     /locus_tag="KOU88_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210836.1"
                     /translation="MNQIELDLYHDMVNIYKEADLQCNYKPTRFLQLINNKGALLAAK
                     ELINKEGATEGFTRLWECKRLDLSLEVLVLKEKYKELFTDEEREICINRLKDYGYKFN
                     "
     gene            complement(43704..44804)
                     /locus_tag="KOU88_000930"
     CDS             complement(43704..44804)
                     /locus_tag="KOU88_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBK3210837.1"
                     /translation="MEYIKLNELCYINIGKTPSRNTSDYWGSGNRWLSISDLKEKYIS
                     KSKEEITDLAVEKANMKLVPKNTVVMSFKLSIGRVAILKEDMFTNEAIANFQIKNNEL
                     ITSEYLYYALRTLNFNNTDRAVMGATLNKSKLNDIKIPYFTICIQNKMVKVLNKAQEL
                     INKRKEQIEALDELVKSRFIEMFGNVITNSKDWDTELLGEISNLKAGKNIKAKDIYEK
                     NSHELYPCYGGNGLRGYVKMYSHKGTFNLIGRQGALCGNVKYVNGKFYATEHAVVVQP
                     KVDINSYWLYFTLKELDLNRLSTGAAQPGLTVGKLNEVEIPKVPVYLQNKFVDFVRQI
                     DKLKSRMEDSLKELENNFNSLMQKAFKGELFN"
     gene            complement(44808..46271)
                     /locus_tag="KOU88_000931"
     CDS             complement(44808..46271)
                     /locus_tag="KOU88_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HBK3210838.1"
                     /translation="MITGELRSKVDKIWETFWTGGLTNPLEVIEQFTYLLFIKGLDEV
                     ETKNEAEATLLGVSFERIFDDEHQHLRWSKFSNEGNSEKMYEIVQNEVFPFIKKLHGN
                     KDSAYAKYMGDAIFKIPTPLMLSKIVDGISNLELSKDRDTKGDLYEYLLSKVATAGTN
                     GQFRTPRHIIDMIVRLIKPTPEDIIVDPAAGSAGFLVSSQQYLRDNHSSLFLVQGLKE
                     HFNNGMFYGFDMDRTMLRIGAMNMMLHGVDNPNIEYKDSLSEVNTDKDKFTLVLANPP
                     FKGSLDYEAVSADLLKVTKTKKTELLFLALFLRVLKIGGRCACIVPDGVLFGSTGGHK
                     SIRKEIVDNHKLEAIISMPSGVFKPYAGVSTAIMIFTKTGTGGTDKVWFYDMKADGYS
                     LDDKRNEIKDSDIEDIIKRFDNLDGEVDRKRTEQSFFVDVEEIRENGYDLSINKYKEV
                     VYEEVVYDAPSVIIGRVRELEKEIAVGLEELERMLEV"
     gene            complement(46781..47650)
                     /gene="gatY"
                     /locus_tag="KOU88_000932"
     CDS             complement(46781..47650)
                     /gene="gatY"
                     /locus_tag="KOU88_000932"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBK3210839.1"
                     /translation="MALVTTKQILLDAQEGHYAVGAFNVENMEMVMAVIEAAEELKSP
                     VILQTTPSTIKYAGLDYYLANVKVASEKASVPVAMHLDHGSSFGLAMQALRVGYTSIM
                     IDGSHESYEDNISISKSVVDACMPSDIPVEAELGKVGGKEDDLDGGDGGAYTDPLEAK
                     EFVERTGVSSLAVAIGTAHGLYKGEPKLDLDRLSEIRDVVSVPLVLHGGSGIPDEVIK
                     ESIKRGICKVNYATELRIAYSNGVKDVLNSDPEVIDPKKYGKKGLESVKDFVKSRMEV
                     CGCVGKAIEIVKC"
     gene            complement(47670..49586)
                     /locus_tag="KOU88_000933"
     CDS             complement(47670..49586)
                     /locus_tag="KOU88_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HBK3210840.1"
                     /translation="MGKKMILGVTGCPTGIAHTFMAEEALKNSARELGCDIKVETNGA
                     IGVENKLTAKDIEMADAIIVACDKNVDMDRFNGKPVIEVPVKEGIHKANELIQRCIDG
                     KVAIRKGNLSSSKIAEEGNLSFGQKLYKDLMNGVSHMLPLVVAGGVLTAISFLWGIYS
                     FDPNSEQYNQIAATLKSVGGYSMNLMVPVLAAFIAQSISGRAGMLAGLVGGMISFDTG
                     SGFLGGIISGFLAGYLVKLFVHLLRKLPRQLEGLKSIFIIPIVSVGLVGVAMLLLGGP
                     CSALNNAMMNFLSGLQNSSPIILGIVIGCMSAFDMGGPVNKAAYVTGTMLLGQGNYLF
                     MAGVSAACITPPLVIAIASTLFKNRFTEEDRAAGLINYILGSTHITEGAIPFAAKNPL
                     KVLPVLMIASSISSILTYIMKIEVPAPHGGFLVLGLVNKPLLWVGCIFVGSLVGAVLY
                     MMVTPKVVNEKNTIENTNVTKDEHKNESAESENVSNNISLYSEETVILDVKGKNKTDV
                     IDEMIGILDKSGVLLDKKKFKEEILKREEISSTGFGMGIAIPHAKTDAVKVPRVAVGV
                     SKEGFDFESEDGSLAHIIFMIAATDNGDNLHLKTLSQLSSKLMNEEFLNELLNSKTSR
                     EIVSKLNNEEIKSV"
     gene            complement(49589..50509)
                     /locus_tag="KOU88_000934"
     CDS             complement(49589..50509)
                     /locus_tag="KOU88_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase family hexose kinase"
                     /protein_id="HBK3210841.1"
                     /translation="MIYTLTTNPAIDMNISTNGIKRKLVNRTSNAVYSPNGKGLNVTF
                     VLGHYGIESKILGFFGGFSGKYIVEESEKRGFDVLPTWVEDTTRINIFLNDGSDEFKF
                     VNSGSYVNEKQKLDMLDKIQSLADISYLSISGSLPPGIDDNYYEDIFKICKNKSIKTI
                     LDISSPKLKELLQYNPYLIKPNDEEIKDIFGIIVRDEEDIKDVLKLLHLKGAQNILLT
                     LGEKGSYFYNGKSIYYASAQPVTVVSSACAGDSALAAFLSIWLENPEHIEEALKRSAA
                     TGASVAESNGIGNLENVEDYIKNIRVRKVV"
     gene            complement(50611..51363)
                     /locus_tag="KOU88_000935"
     CDS             complement(50611..51363)
                     /locus_tag="KOU88_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3210842.1"
                     /translation="MIIELNKSNSENLTKTELEIIKFINENESILPELSIVEIAHETY
                     SSPATVSRAIRKCGLNGFNELRYRLTVKDENDDIQNMGDIINKSFIEAQRVIEQISLT
                     TLINIIKTINKSSKIYILARGLTEYVAKEFSLKLQLLDFNVVFINDPNIMKIKSKSIK
                     KDELIIIFSLNGNTIELVESAQNANLVGAKVITCCCSESAKLIKYSDLYIVGYKHEHI
                     SISEYEVSSRLPLYIISRIIIDYMVRYNNSEN"
     gene            complement(51755..53200)
                     /locus_tag="KOU88_000936"
     CDS             complement(51755..53200)
                     /locus_tag="KOU88_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK3210843.1"
                     /translation="MIKLGKFPKGFLWGGAVAANQLEGAWNEGGKGWCLADVHMYDKD
                     RDISKPYESDMTIERIKFAMKDNNGYYPKRSGIDFYHTYKEDLKLLKELGLKCFRFSI
                     NWARIFPNGDDLEPNEEGLKFYDNLINEVIDNGMEPIVTLLHYETPLNLVLKYKGWSN
                     RKVVDFFVRYAELILNRYKNKVKYWIVINQINLIHYESFNSVAFCVDQVDNVEETRYQ
                     AIHHQFIATALTKKLGKEINSDMMIGMMMADCTSYPEDCDPENVVFALKRNRLQYFFT
                     DVSFRGEYPVYIKRFFKENNINIVMEEGDDKILKENTMDFLALSYYYSTTVSASKNTM
                     NPTDNIKNPYLKANPWGWAIDPKGLYNTLSQYYDRYQKPIMIAENGFGMHDKFEDGKV
                     HDSYRIDYLGKHIEQIGEAIADGTEILAYCMWSPIDIVSCSSQEMEKRYGFIYVDIDN
                     NGNGSKERYKKDSFYWYQNVIRTNGEELREK"
     gene            complement(53222..53575)
                     /locus_tag="KOU88_000937"
     CDS             complement(53222..53575)
                     /locus_tag="KOU88_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK3210844.1"
                     /translation="MTIEEHIIDEELVEVAMQIILRAGEARTEIKHALNDLEKFDYRN
                     ADLKLAKAKGFMTEAHRAQTKIIQGEAGGEKRAHSLLFAHAQDTLMTIFSELNITMSL
                     VGIVKSIEYKVNNSK"
     gene            complement(53604..54851)
                     /locus_tag="KOU88_000938"
     CDS             complement(53604..54851)
                     /locus_tag="KOU88_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3210845.1"
                     /translation="MGRVFMNKFIDFLSEKFTPVVNNMTKNIWVQSVQSTIMKVLPMV
                     FVGSLVTIVSVLKNYISFLPDLSPINQYTFGLLGLFIAFLLPMETMKNKKFESMSVVA
                     GLAGAGLMLMMIRPEITNEGAIFNFNRFGGEGMLVSLVAGLFSGLIMSLFGSFSFFGE
                     DSALPDFVSKWFDNMLPITVIMFVGWGLIYGLNFDMFEIIVRVFKPVSDIAQTLPGFV
                     LLNFLVVFIYSLGISGWVLSPITYSIQLGAIAANAAAVASGGVATNIYVYEVIQTGWI
                     TLGGLGATLPLVIMMCLSRVGRIKAIGRACIVPSIMNINEPVIFGAPVAWNPFLMLPM
                     WIGTVVISITTYLSMSMGFVTIPSKVFNLWYVPFGISTFMVNQDVRGLIVLAINIVLL
                     FMIWYPFFKAYEKEEIKLESQEV"
     gene            complement(54859..55176)
                     /locus_tag="KOU88_000939"
     CDS             complement(54859..55176)
                     /locus_tag="KOU88_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3210846.1"
                     /translation="MKNIRVLLACGSGASTGFMATSMRKSAKKKGIEADIKARSESEI
                     DKYLSEIDCLLLGPHLDYMKEEIQQKANEYNVPVACISKTAYGRLDGAKALEEALELI
                     SNK"
     gene            55418..57331
                     /locus_tag="KOU88_000940"
     CDS             55418..57331
                     /locus_tag="KOU88_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3210847.1"
                     /translation="MKTSKKELFLNFIKTQHDWIDSSTLANYLNVSTRSIRKYVNEIN
                     SNGAFILSSKKGYKVNLNTNCQTKIDSSENISPDNRLNLILKELIVNSNGINIFDLSE
                     ELFVSPATIEGDIVKANKFIGSYNLKIKQSKFLLKLVGNESAKRKLMSSIIFKETGSD
                     FLSLFDVQKIYQEYNLTKLKENIIYILKKYNLFINEYAINNILLHLMITIDRIKKNNY
                     IDSVEVVNYIDNNVDINIAKDISNFLESEYNITLTSAELYYLVFQLTNKTTVLNYNQM
                     DTKSLSNYIDEHFVKLTKKIIKNVYDLYLIDLSDEEFVVKFTLHVKNLISRAKNNQVL
                     RNQIPQKLKDSYPLIYDISVYICNQIQTLENVDIDEDEISYISLHVGSFFDRQKLLED
                     KVLCALITPNYYDLQFKIVRDLEKRFNESIEIIQIFSDTHNLDFDNKVDMVITTLPIN
                     DRCPIPFVYVNPYLNRKDYDNIQSKFIQIKDRKNILTVQNHLEMYFSESLFMKNIYLD
                     SAKDYIRFMGNILYENKYVKPNYIDDVLIREKMSSTAFNNNVAIPHSMKMDALKTGVC
                     LIVNDKPVKWGEEKVQIIAMIPINEKEKEKFNYIFESFIEILSEWNNVKELTKADNYS
                     SFMNRIAYLIQNI"
     gene            complement(57454..58608)
                     /locus_tag="KOU88_000941"
     CDS             complement(57454..58608)
                     /locus_tag="KOU88_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBK3210848.1"
                     /translation="MKMLISIDSLKGSLSSIEAGNAIKKGILKVKEDAQVKILPLADG
                     GEGTVDALVQGMNGKKETIEVTGPIAKKVDATYGLLKNTSTAIIEIAQASGLTLVPTE
                     LRNPLYTTTYGVGEIIKEAINKGYRNFIVGIGGSATNDAGIGMLQALGFEFYDKNNKL
                     VGLGGKVLNEIRHIKIENRLKELDECKFKIACDVNNPLFGKNGAAYIYGSQKGATSEI
                     IEELDNGLRNFSKVVKNYLSKDVANVEGAGAAGGLGFAFLAFLDSKLESGIKIILEEI
                     KLEEELKDADFVITGEGRLDNQTAMGKAPIGVAKLAKKYGVKVIGLAGATTEDAVKCN
                     EEGIDAYFSIVNRAMTIEEAMDKATASENMTATTTQIFNLITSIQQSKNM"
     gene            complement(58887..61502)
                     /gene="mngB"
                     /locus_tag="KOU88_000942"
     CDS             complement(58887..61502)
                     /gene="mngB"
                     /locus_tag="KOU88_000942"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HBK3210849.1"
                     /translation="MKKNVHIVPHMHWDREWYFSTEESRILLVNNMEEIMDMLENNHN
                     YPYYVMDGQTAILEDYLAVKPECKERIKKLVQEGRLIIGPWYTQTDEMVVGGESILRN
                     LLYGIKDCDEFGEYMKIGYLPDSFGQSAQMPQILNGFDIKYSMFWRGCSERKGTNKTE
                     FNWKSDDGSSVLVQILPLGYAIGKYLPMNEDELRTRMDKYLPVLDKGATTDHIILPNG
                     HDQMPIQKNIFEVIYKLKECYPDRKFFLSRYENIFKELEKNEDIDTIKGEFLDGKYMR
                     VHRSIFSTRMDIKSANARIESKITNILEPLASIAYSLGFEYHHGLIELIWKEIMKNHA
                     HDSIGCCCSDKVHQEIMNRFFLAEEKVDQLITFYKRRIVDAMSCEMALDKLIAFNLMP
                     YDRNEIVSAQVITKMKAFEIFDKDNNKLDFEVVHKEVIDAGLIDRQIVHYGNYDSFMV
                     YTINFKDKIPAMGYKAYMIKEVEHMLEKAYEVCDMVDNDFYTIQVNENGTLKIFDKKL
                     NKTFENVLLMENGGDEGDEYDFSPLPNEKLIFNDNIVANSTIKKNRFNNEIKINYRLK
                     VPKDIQARKNNRADSFIDFDIVINVPNDKAIIDVVFNINNQARDCRVRTYIPTNIASK
                     FSVSDNQFGHIKRSVYDDAMEVWQQEDWSERPDSIYPMLTFVGLSDKEHGVAVLTNST
                     REFEIVGEKFDTIAITLFRSVGFLGKEEMARRPGRPSGIKLHTPDSQMIGDIKIDLAI
                     VTHEKSTLEANVANMAKEYLTKIQTYNKMPYNAMKLNQSEIEVDYSYSLLKETNKDLV
                     LSVVKKAEKEEALVVRFYNSKEETKSANIVFNKNIKTAKWINLNEKELESISIDNNSV
                     NVECLMNQVKTILVK"
     gene            complement(61646..63556)
                     /gene="mngA"
                     /locus_tag="KOU88_000943"
     CDS             complement(61646..63556)
                     /gene="mngA"
                     /locus_tag="KOU88_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007708766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HBK3210850.1"
                     /translation="MIRNLVSFLKQKIKTKEDAIKFLARKLYDEGKLTSYEEYLEAVM
                     YRETLSPTGFERGLAIPHGKSKSVKEAAFAAMTLETPIENWESVDPNNKVELIFLIAV
                     PESEGGNTHIQILSELVTRLSNEDYMNMLLNSKTKKELFNNLDIKEKKEQIKEEIRIQ
                     NESKKIILAITACPAGIAHTYMSAEALIKAGKEIGVDVYVEKQGANGMVDPHTPDIIK
                     RADAIIYATDVAPKNTERFEHLPNIKTSVAAPLKRAKEIIYEALEVAQKQGKGDYIEK
                     SSDISYCEKSSWKKDVKSAILTGVSHIIPLIVAGGMILAFAVLASQAFGLQELYNQEG
                     SWLWQLRKLSGGMLGTLMVPVLSAYMSYSLAEKPGLGPGFAAGLAADLIGSGFLGGML
                     GGLLAGYIVKFLKKNIPAKGTLAGFVSFWVYPVVGSLVVGLLMLFVVGKPVAALNNGL
                     INWLNGMTGVNAILLGAIIGAMVSFDLGGPINKAAYTFAIGAIASGNFIPYAIFASVK
                     MVSAFGVTIATVLGRDLFSESEKEIGKQTWILGLAGITEGAIPFMIEDPIRVIPSLVA
                     GSAITGSIVAFFNIGLQVPGAGIFSLALLEGSMSGFIIASIWFFAAVLGAIISAILLI
                     ITRKQKNQRKIH"
     gene            complement(63707..64897)
                     /locus_tag="KOU88_000944"
     CDS             complement(63707..64897)
                     /locus_tag="KOU88_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006354938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK3210851.1"
                     /translation="MSKVKRQDSKGRNLRLGESQRKDGRYVYKYTDIFGKPQFVYAWK
                     LVPTDKTPAGKRDDISLREKEKQIKKDLDDGIDTVGGKMTVCQLYEKKNNQRKNIKRN
                     TKIGRQYLMNALENDPLGMRAIDTVKQSDAKEWAIRMNDKGYSYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFNFKLSDVLEDDTEAKVILTPEQEEKLLAFMETDNVYSKYRDEVI
                     LLLETGLRISELCGLTTHIDMLNRVINIDHQLLRDTEVGYYISTPKTKNGKRELPLTE
                     RAYQALERILKNRGKAQPLVVDGYSNFLFLNREGLPKVAGNYESMVRGLIKKYNKTHK
                     DKLPNITPHSFRHTYCTNMANKGMNPNTLQYIMGHANITMTLGYYAHGTFQSAKAELE
                     RLAS"
     gene            complement(64975..65178)
                     /locus_tag="KOU88_000945"
     CDS             complement(64975..65178)
                     /locus_tag="KOU88_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBK3210852.1"
                     /translation="MNNTDVPIWEKYTLSIEEASRYFRIGEKKLRRLAEENLDSGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            complement(65551..65805)
                     /locus_tag="KOU88_000946"
     CDS             complement(65551..65805)
                     /locus_tag="KOU88_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3210853.1"
                     /translation="MKKKYKHPSYYLISSAMDGDETAIEKLLVFYDPYISKCCLRPLY
                     DEYGNVYIVVDMELKGRIREALIKMILDFEIDIDIETEEE"
     gene            complement(65808..66227)
                     /locus_tag="KOU88_000947"
     CDS             complement(65808..66227)
                     /locus_tag="KOU88_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009261829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3210854.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVVKGIIWNYRKELKRRKNKEISFS
                     ELPDITVESLATWDDYETNYTIFNVCGIDIKVLDDELAEALKQLPEKKRNNVLMYYFL
                     EMSDTEIADIMNYTRGAVFKHRHRALETMKEILKEKK"
     gene            complement(66494..66724)
                     /locus_tag="KOU88_000948"
     CDS             complement(66494..66724)
                     /locus_tag="KOU88_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210855.1"
                     /translation="MIGLKRRNMNYIMKVGAKAQGVSVSEFRAMLQDTIDKTMESTDP
                     DVQANFKRYFGNKRPTPEEYIYTITKKTKVKV"
     gene            complement(66748..66939)
                     /locus_tag="KOU88_000949"
     CDS             complement(66748..66939)
                     /locus_tag="KOU88_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003064779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4177 domain-containing protein"
                     /protein_id="HBK3210856.1"
                     /translation="MKKYEYVEINYNAKGVVFLCTDKHKEIIDSYAKTGYHYAGFVPT
                     EIDAKGCMRKIDLIFEKED"
     gene            complement(67103..67819)
                     /locus_tag="KOU88_000950"
     CDS             complement(67103..67819)
                     /locus_tag="KOU88_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK3210857.1"
                     /translation="MEYIRSKKYFTPDLQTKIMGPNPIKLQEELLQNHKIPSGSYVCD
                     LGSGQGLTSVFLAKEYGFVVFAVDLWSEPKENEEFFKKMGLSSAQIKSVKADANELKF
                     EKEFFDAVVSTDSYNYFGRDPIYLDEKLLPFVKKGGFVYITVPGMKKDCHEKLPEELL
                     LSWTPEELDYIHDITYWSNIISHCKKADLISIYEMESNSEVWSDWIKQNNEYAINDRK
                     AIEAGGGDYLNFIAIILQKK"
     gene            complement(67853..67942)
                     /locus_tag="KOU88_000951"
     CDS             complement(67853..67942)
                     /locus_tag="KOU88_000951"
                     /inference="COORDINATES: protein motif:HMM:NF025568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210858.1"
                     /translation="MIIFCPECKHNFLISAEELKMNIVISHKY"
     gene            complement(67939..68565)
                     /locus_tag="KOU88_000952"
     CDS             complement(67939..68565)
                     /locus_tag="KOU88_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3210859.1"
                     /translation="MSDTKENILKIALHLFAVNGYEAVSVSMIAEALGMTKGALYKHY
                     KNKQDIFDCIVERMYQIDNKRAKDYQVPESTIEVTPNAYRNTTIGSLITFTLAQYDFW
                     VTDEFASNFRKMLILEQYRNLKMNVLYQKCLVNGPISYIEDIFNEMIKKGVLQECDTK
                     QLAIEYYAPLFLLISVADAVENCWDLKSQLTTHVNQFVKKYITIEKVK"
     gene            complement(68857..68997)
                     /locus_tag="KOU88_000953"
     CDS             complement(68857..68997)
                     /locus_tag="KOU88_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210860.1"
                     /translation="MEQYWWIIIVVVLIVVGLLKIVIMKKYNQRRNSNNRSKDSEDDK
                     MY"
     gene            complement(69049..69960)
                     /locus_tag="KOU88_000954"
     CDS             complement(69049..69960)
                     /locus_tag="KOU88_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBK3210861.1"
                     /translation="MEKGRLLQNGKVNRAIQVSKITLFINLSLSLLKFAAGYIGKSSA
                     MLSDAVHSASDVLSTIVVMVGIKISEKQPDREHPYGHERMECVASIILSVALAITGAG
                     IGYSGIKKIFSGQYNTLSVPSGIALTAAVLSIVIKEWMYWFTRNAAKHTNSDALMADA
                     WHHRSDALSSVGSLIGILGARLGYAILDPIASVVICGCILKAALDIFKESINKMVDHS
                     CDNATETKIREVVLQQQGVDGIDELKTRMFGAKMYVDIEILADGNLALYDAHRIAEGV
                     HQTIENNFPQCKHCMVHVNTNELLYSA"
     gene            complement(69972..70670)
                     /locus_tag="KOU88_000955"
     CDS             complement(69972..70670)
                     /locus_tag="KOU88_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002583502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210862.1"
                     /translation="MKRILSSTIQVFRQIKSDPMMFAACFTPFVMGALIKLGIPFLER
                     ITDFSLRAYYPIFDLLLSIMAPVLLCFAFAMITLEEIDDKVSRYFSITPLGKSGYLFT
                     RLGVPSIISAVIAFIVLLLFSLEKLSIGMTICLALLGSVQAIIVSLMIITLSSNKLEG
                     MAVTKLAALTLLGIPAPFFIDSYYQFAVGFLPSFWVAKAMQNEAVLYFSIGLVVALVW
                     YYFLTKRLFRKLAG"
     gene            complement(70667..71350)
                     /locus_tag="KOU88_000956"
     CDS             complement(70667..71350)
                     /locus_tag="KOU88_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016295773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3210863.1"
                     /translation="MRLGRLIRGDIHFQWKYGFYFIYFILTVLYVCGIAALPEHWKTD
                     IASIMIYSDPAAMGLFFMGAIVLLEKSQKVLNAMVVSPVKISEYILSKTVALIAISTV
                     IALILGVVSGSNHLLGITVGTALTSAIFTMLGIIAATKISNLNQFLIVIMPIEIVCFA
                     PPIVGLFVKLPYLFRFFPFTACMNLITGKSVLLSFDMVLVIATLIILYIVARHTVKHM
                     WKSLGGVKL"
     gene            complement(71347..72192)
                     /locus_tag="KOU88_000957"
     CDS             complement(71347..72192)
                     /locus_tag="KOU88_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3210864.1"
                     /translation="MIDVKKLYFSYTDKPFVENVSFHVGRGEIFGFLGPSGAGKSTIQ
                     KVLTGLNTRYKGSVKVAGTEIREHTNQFYENIGVDFEFSTCYEKFTARQNLAYFASLY
                     EKQPRSIDELLHMVGLENDGDKKVADFSKGMRSRLNFIKALVHDPDILFLDEPTSGLD
                     PTNSRLMKDIILAEKKRGKTIIITTHNMFDATELCDQVAFIVAGKVSALDSPHNLIMS
                     RGAAKIQYTYYDKGEKTGECLLDRTTEDKLLKSLISENRLLSIHSSEPTLNDIFVDIT
                     GRTLQ"
     gene            complement(72296..72877)
                     /locus_tag="KOU88_000958"
     CDS             complement(72296..72877)
                     /locus_tag="KOU88_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3210865.1"
                     /translation="MPRFTEQEKEIINSKLLIEGEKLFALHGLKKVTVDDLVAAVNIS
                     KGSFYAFYPSKEHLYVEINFRLQKELFTSIETTIKKKKYKNHRDLAKDVIMLSLTGVI
                     TSPILSQIDLSLMDYLQRKISSDIFENHMYSDIRILEILEDLGVIFLVPHTVIIKSLY
                     SVLSCLEQFKEDEELNMIQNLLVNGIIQQVVAE"
     gene            complement(72955..73812)
                     /locus_tag="KOU88_000959"
     CDS             complement(72955..73812)
                     /locus_tag="KOU88_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002585362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3210866.1"
                     /translation="MYKEVGISSNNVPITLSIWYTERSSPTIVFLPGTMSHPLMYENF
                     LCGLSERGFNIIGVHYLSHGKSPKIKKNYIMEDMLHNVYDATTYGIETFGENIAVMGS
                     SQGGILAAMAAGRDTRLKAVFPHNIMLTTLKETMSLTKYPAWSHRFMGLIQWGFRVGG
                     KLLPNYKVPGDAYLDYDRVFYSEQAKQDCLNDPMLLPYYPLRFVASLFNADLSCLENG
                     AIQCPVILITAKGDPLFSFDYTNKVFDLIHVPQKELLALELNRHMIFNEDTDTTINAL
                     EATLHKYLG"
     gene            complement(74025..74494)
                     /locus_tag="KOU88_000960"
                     /pseudo
     CDS             complement(74025..74494)
                     /locus_tag="KOU88_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892232.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(74510..74707)
                     /locus_tag="KOU88_000961"
     CDS             complement(74510..74707)
                     /locus_tag="KOU88_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210867.1"
                     /translation="MLKQGAKLSGVPLSEIQENIEATIDEAMNSTDPEVQANFKKYFG
                     NKRPTPEEYIYTMTKKSRFKV"
     gene            complement(74821..75438)
                     /locus_tag="KOU88_000962"
     CDS             complement(74821..75438)
                     /locus_tag="KOU88_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005951992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBK3210868.1"
                     /translation="MKNNIMLILPIAFILDLLIPFILAPTYRGYSHLTQVMSVLGNSK
                     APLHNVYNTWLVIFGMTLAVINFKVYAVVSKGSRLIAIILFIVLLIYAIGGCILSGLF
                     SVGEVKSLNTLSEKIHGYGSVVGFMCLSFAPLLLGIYAYKINDIKFSFFCIGCFILAI
                     LCFSCFVMGDKPNFRNTFLAFEGLWQRLSLLFMYFPLGCLILFET"
     gene            complement(75428..75667)
                     /locus_tag="KOU88_000963"
     CDS             complement(75428..75667)
                     /locus_tag="KOU88_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008791134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBK3210869.1"
                     /translation="MPMKKGQHIFGTVKVGEKGQIVIPKEARQIFDIKAGDTLLVLGD
                     EEQGIAIVKADVMKELAVKILKGLGKLSNGIDDEK"
     gene            complement(75800..76654)
                     /locus_tag="KOU88_000964"
     CDS             complement(75800..76654)
                     /locus_tag="KOU88_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210870.1"
                     /translation="MRTVKVGTHKKSVIALWVVLIASVSFGVYKNFTAIDMHTVHETE
                     TIQLRLNDTNGIENFVKNFCKSYYTWDNSKEAIEARAQAISNYLTKELQDLNLDTIRT
                     DIPTSSIVTNVLIWDIEQSGTDDFIATYEVDQQIKEGEQTTNVKATYTVKVYVDKDGD
                     MVIVQNPTLAPAMEKSDYEPKAQEADNSVDADTTADATAFLETFFKLYPTATETEIAY
                     YVVGNALEPINGDYLYSELVNPVFTADEDNIKVKVAVKFIDNQTKATQISQYELTLHK
                     DGNWKIIG"
     gene            complement(76708..77324)
                     /locus_tag="KOU88_000965"
                     /pseudo
     CDS             complement(76708..77324)
                     /locus_tag="KOU88_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896986.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
     gene            complement(77591..78142)
                     /locus_tag="KOU88_000966"
     CDS             complement(77591..78142)
                     /locus_tag="KOU88_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3210871.1"
                     /translation="MSLQDYIFEKPVIETEHLILRTMNKNDIDDLKEWISDISLYEYW
                     GKRPSKNEKNPELLFNKPEKATKSFHWGIVHKQDSKVIGELWIYLIENDRMAKVAFRL
                     SKQYQGNGLMSEVLKGVIEFCFSKTELQKIWTDVHILNHASYKTLEKVGFQREGHIRE
                     GKMVNTYCDYYLYGILKSDYIIS"
     gene            complement(78156..78632)
                     /locus_tag="KOU88_000967"
     CDS             complement(78156..78632)
                     /locus_tag="KOU88_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBK3210872.1"
                     /translation="MTTYKVNSIGTIYNNEKGAFIQLEAPYIPALKELDGFSHINVLW
                     WFSDFDNADFRSVLETDQPYKKAPEKMGIFATRSPVRPNPIALSAVEIINIDYMSGLI
                     QIAYIDANDKTPILDIKPYTPSLDRVENPQVPDWCSHWPHSLEESASFAWENEFNF"
     gene            complement(78713..79528)
                     /locus_tag="KOU88_000968"
     CDS             complement(78713..79528)
                     /locus_tag="KOU88_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBK3210873.1"
                     /translation="MFKIGEFSKLTQVSTRMLRYYDETGLLKPAKIDSLTGYRMYSAE
                     QISTLNRIIYLRDSGFNVAEIALALACSNDTIIEQLDKKSIEIMDNIQKEQEKLKKIE
                     IAKKELLHGKSELYFNITIKEIPSYCVLSLRKEIPNYYYEGELWKELSAFAKENKINI
                     SDETFSIYHNEEYKEKDVDVELCTIVNKIGKATGDFKFRFTEPVSMMACTMVYGDFSN
                     ISYAYRSFAKWLQENSQYKMKGSSRQIVHRGPWNEKNPENYLTEIQIPLENLL"
     gene            complement(79631..80533)
                     /locus_tag="KOU88_000969"
     CDS             complement(79631..80533)
                     /locus_tag="KOU88_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210874.1"
                     /translation="MFKKNKKQTENIKEKKVRTVKVGTHKKTVIALWVVLIASVSFGV
                     YKNFTAIDMHTIHETETIQLRLTDTNGIENFVKNFAKSYYSWNNSKEAIDARTQAISG
                     YLTKELQDLNVDTIRTDIPTSSAVTDVIVWNIEQFGTDIFSATYEVDQQIKEGEQTTA
                     VKATYTVKVHVDADGDMVIVQNPTLAPAIQKSDYEPKTPEADGKLDADTINDATAFLE
                     TFFKLYPTATEKELAYYVAGNVLEPIGRDYLYSELVNPILTKDGDNVKVKVAVKFLDK
                     QTKATQVSQYELVLHKDSNWKIVG"
     gene            complement(80553..81557)
                     /locus_tag="KOU88_000970"
     CDS             complement(80553..81557)
                     /locus_tag="KOU88_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK3210875.1"
                     /translation="MKLKHIAIIGSLFPILFSIVLFFGVLISADTDDDNSNFSSGITG
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGIDDLNVAIQSYNYGGGYVGYVAGKGKKHTFNLA
                     ENFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQISGELAQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLVQWCYGKAGISLPRTAQTQYDATQHIPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYADLSSSYWQQHLIGAGRVK
                     "
     gene            complement(81554..83740)
                     /locus_tag="KOU88_000971"
     CDS             complement(81554..83740)
                     /locus_tag="KOU88_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK3210876.1"
                     /translation="MKERIQSAFTKKKIFHFLKMALFVVALSLILLSLLGTMAHATGL
                     VDDTINAENLYSKYPLSNYQLDFYVDNSWSWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGKSIQTLAGVTQNGFSSTGFYVGFLLLIIL
                     VVGLYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNENNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNANDSQSMGRRIFRRP
                     YLYMAHRARRMERRLAGAVTAGGVAGAVAGSTISNGKPTRKTSTKDSRGNTSSSSMGQ
                     RAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVHSAKEKAKTSVSDFKRGVVQ
                     EQQSRQTGRSEKLEQHKKNIADKRMELQKAQEARQARKMDGSATTGATRSHERPATAL
                     KPSVEKTQEVKRPATTSTSKVSEPVKTNGVKERPLSSGASDRKTTQSAQPVYRQNIEK
                     VVSQETRQNYKTERTTKTQTFEQSKHTTEHTEKNRNLVTKKGQKKK"
     gene            complement(83740..86190)
                     /locus_tag="KOU88_000972"
     CDS             complement(83740..86190)
                     /locus_tag="KOU88_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210877.1"
                     /translation="MYPIKYIDNNLVWNKDNEVYAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKRLVTGKLREVAVRKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSAWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIDDFGYLMEHLYGRDGIAYEDYEYQLPKKKYKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFTFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGSETSSNVVDALDSVD
                     ELETDLDQTKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDLNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYSVLFGGQAVILDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKVVRSVTQSETRGLLHVIDELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPDKDTTFNEYTTIELLSVAMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSAYDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPIQRNEVE"
     gene            complement(86177..86566)
                     /locus_tag="KOU88_000973"
     CDS             complement(86177..86566)
                     /locus_tag="KOU88_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210878.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFFI
                     ILFGDMPPLSMVEGAFLKYFGIPVALTWFMSQKTFDGKKPYSFLKSQITYALRPKITY
                     AGKAVKLDKQILNETITAVRSVNYVPD"
     gene            complement(86676..87179)
                     /locus_tag="KOU88_000974"
     CDS             complement(86676..87179)
                     /locus_tag="KOU88_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK3210879.1"
                     /translation="MIDDMAVYIANLGKYNEGYLVGAWFTFPIDEEDVKEKIGLNEQC
                     EEYAIHDTDNFPIEIGEYVSIEELNEMYEMIEELPDYIVECLDEFIGHYGTLEEVMEH
                     KDNIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDMGGCFIATSR
                     GMCEIPY"
     gene            complement(87197..87700)
                     /locus_tag="KOU88_000975"
     CDS             complement(87197..87700)
                     /locus_tag="KOU88_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK3210880.1"
                     /translation="MQETRVLVETSGTTGEETTSYWFDLPIDVAEFEEKLGVGAESGD
                     YRIIEKVLPFADEVHEHTSVYQLNELDFMYRQLSSDMQEEYTALLTVYENLEALYICR
                     NVIAVYPDCKSMIDVARQKLMNDPTFKHLSEDCQEYYFDFEAYASHLLENRRYLVTEH
                     AVFELPE"
     gene            complement(87619..87915)
                     /locus_tag="KOU88_000976"
     CDS             complement(87619..87915)
                     /locus_tag="KOU88_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210881.1"
                     /translation="MNDIFKDMQAKVGCENISDLPSYKRKVWHEMKQLNFADYEEKQL
                     EDFSNYVFGMSCQTLKDVMKQQKGREEQCRKQGCWWKRAEQLAKKQHHTGSTCR"
     gene            complement(88019..88561)
                     /locus_tag="KOU88_000977"
     CDS             complement(88019..88561)
                     /locus_tag="KOU88_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBK3210882.1"
                     /translation="MKGFERKNQLFSLCGLNCGLCPMLLGNHCGGCGNGNQSCKIARC
                     SLEHGMIEYCYECKQYPCEKYQHIDDYDIFITSRRQKADLERAKIIGIEQYNLEQQEK
                     TQILSYLLSNYNDGRRKTFFCVAVNLLELSELQEAMKQIQSNDELTLLPFKAQCLYVV
                     EMFQKIADRRNIKLKLIKKK"
     gene            complement(88636..89166)
                     /locus_tag="KOU88_000978"
     CDS             complement(88636..89166)
                     /locus_tag="KOU88_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009298863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3210883.1"
                     /translation="MCKILLVRPSKQYADQVMSYKEEMSQNGDSFDGCAGLENVQSFE
                     EWIDFEARLKAKYKDGYVPSEVFLAIRKKDNYVIGMIDFRHPLSDFLFNFGGNIGYSV
                     RPSERQKGYASEMLRLILPICHEFGESKVLLTCDKKNEASQKTIVRNGGVLEKEIPDT
                     VGLSESGIIQRYWISI"
     gene            complement(89250..89471)
                     /locus_tag="KOU88_000979"
     CDS             complement(89250..89471)
                     /locus_tag="KOU88_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210884.1"
                     /translation="MNFGQNLYTWFLSNAQSLVLMAIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            complement(89472..89606)
                     /locus_tag="KOU88_000980"
     CDS             complement(89472..89606)
                     /locus_tag="KOU88_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBK3210885.1"
                     /translation="MWELLKDLLLVSFGIGIGVVLMCILTVGKEADRCMEEIKEREDN
                     "
     gene            complement(89614..90813)
                     /locus_tag="KOU88_000981"
     CDS             complement(89614..90813)
                     /locus_tag="KOU88_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBK3210886.1"
                     /translation="MNETDFLTALKEKRCAYGVSQTRLAIMANISREHLSRIEAGKVT
                     LTEDMKHTLLEAVEKFNPDNPMFLLFDYVRIRFPTMDIKHIIKDILKLNIDYMLHEDY
                     GHYKYTEHYHIGDVFVYVSQDEEKGVLLELKGKGCRQFESYLVAQERSWYDFFTDALV
                     EGGVMKRLDLAINDRTGLLDIPELIQKCEHEECISKFRSFKSYGSGELVKHNETDKYD
                     MGHTLYIGSFSSEVYFCCYEKNYEQYAKLGIPIEEVPIKNRFEIRLKNERAYYAVVEL
                     LTHYDAELTAFSIINQYIRFADKEPDKRKSDWKTNVRWAWFIGEGRPPVKLTTKPESY
                     TLERTLNWLQRQVAPTLKMLKQIDKDNQTEYLETIEKQAKLTERHYQIIKQQTATVEE
                     MVANVKE"
     gene            complement(91015..92409)
                     /locus_tag="KOU88_000982"
     CDS             complement(91015..92409)
                     /locus_tag="KOU88_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008787614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210887.1"
                     /translation="MKMILNKGHRIRASDKNLVYHFSIGTLLFVFIAVILLLNMKQLM
                     RTDWEHFSLLDNGLTLSTYNFITLLIATGVCALVAFLYYRFCYDSFKKLLHRQKLARM
                     ILENKWYEADTVQDSGFFTDLQSRSREKIIWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTMLYDMIANRITIDEVKAENGCLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNADLADLGTVMGNVY
                     HTKEEMIDCVNAFYEGMVQRSKEMKRHPDYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGSLAYARQ
                     DGTATCEAKGDGTD"
     gene            complement(92526..93011)
                     /locus_tag="KOU88_000983"
     CDS             complement(92526..93011)
                     /locus_tag="KOU88_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006776881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210888.1"
                     /translation="MAKEKGSFKEFLSAIAPEHQVFVEKLNTKLIEQGCDLVIKEAKS
                     GYTASYQLEKKTVMNWVFRKTGVFARIYGDNAGKYEDIIASLPADMQKKMTTSRDCKR
                     LIDPNACSDTCVKGFVYALNGDTHKKCRNDGMLFVLTNETAEHIAGLVCAEVNVRKSA
                     L"
     gene            complement(93109..93492)
                     /locus_tag="KOU88_000984"
     CDS             complement(93109..93492)
                     /locus_tag="KOU88_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014080829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK3210889.1"
                     /translation="MRLANGIVLDKEKTFGVLKFSALRHEVRAENDDGSTSEEITRRT
                     YDLKCSVQERMIQVSIPADIPVKDYPYNAEVELVNPVADTVANASYRGVNVDWYIKAD
                     DIILKNKGGQVGNPQNHAPQGQPKK"
     gene            complement(93508..93834)
                     /locus_tag="KOU88_000985"
     CDS             complement(93508..93834)
                     /locus_tag="KOU88_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005337695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK3210890.1"
                     /translation="MELKYVVPNMAQTFGNLEFAGENKIEQQRINGRFTPVSRSYNLY
                     SDVQRADDIIVTIPAKAGEKHFKPEQRVKLINPKITADGKAVKGRGFTNYILTADDML
                     PAEESK"
     gene            complement(94070..97114)
                     /locus_tag="KOU88_000986"
     CDS             complement(94070..97114)
                     /locus_tag="KOU88_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBK3210891.1"
                     /translation="MKKILKRLCTGVLAFATVVTALPTTLVHAESKQYWTESEERVGI
                     VEKVMNDGSIGSTFNEGHLTVEGEDAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSIEYVKQYTASHNEISNNHAYLLRQLVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFAGAKAFVKENKGRYKCGGYIYSGEGQELGQFWAKLNVGNAKLQKTSNNTSITDGNG
                     NYSIAGATYGVFSDKDCTKQLATLTTDNSGNTEVAEVKATTVYIKELTAPMGFKVDKT
                     IYSLKVEAGKTATLKVSDTPKVTDTLIELFKIDMETQKANPQGNASLEGAEFTWKYYA
                     GFYTKDNLPAEATRTWVTKTIAETDSDGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLTCEETKSPTGYLLDGAYMQANGSEEQIKGLYLTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNSVLVEGKLYKKNEVVKTIH
                     TDIEGIASTSADLLPYGNFRIVEKQAPNGYLTDGAKPIDFAITENGKIVDLTDEAHSV
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGESHVVVTDDNGQFSTSSDWASHK
                     HNTNAGKTSEDGVWFGTSEPDDSKGALPYDTYIIEELRSDSNKGFELIPPFEIVVSRN
                     NLVIDLGTLTDEYEKEITIHTTATSKDGEKTILAGKEVTIVDTVKLDGLTKGTKYQLK
                     GWQMLKEENAEIIIDGKRVESDYTFVADDEEMKVEISYTFNASELGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDDGQTVLITERIIKIHTTATDKDGNKELEAGKDVTIIDTVT
                     LEGLEVGTKYKLVGWQMLKEENAELLINGKRVESDYTFIADSETMKVEVTFTFDATSL
                     DDKQLVTFEELYDLSNPNEPKKVTEHKDIEDEGQTITFKEKPEVPEKPETPTTPEKPS
                     RPTDSPKTGDNTNVMAFLVMLLTSAGGLAGTYLYKRRKMKKS"
     gene            complement(97579..98304)
                     /locus_tag="KOU88_000987"
     CDS             complement(97579..98304)
                     /locus_tag="KOU88_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3210892.1"
                     /translation="MEFYERAKKYEYKFTDTEDMIIEYMRKNKEEIVKLSIQSLADKF
                     FTVPNTIVRLCKKMEYDGFSQLKNNLKEELKNEDKEPKNGFESDIKKTLELIDYEKIN
                     KVADIIQKSRSIIVYGIGQNIPLCEILVKEIRGGHDNITYYSQRHEVLHDIGKLGEQD
                     MFFALSLSGETKEVIEAAKTAVNKGCKVVALTHICENQLQQIADISLYCYSTIKQVNG
                     YNISDKVPIMMIMRAIIEQYWLR"
     gene            complement(98567..99346)
                     /locus_tag="KOU88_000988"
     CDS             complement(98567..99346)
                     /locus_tag="KOU88_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ChbG/HpnK family deacetylase"
                     /protein_id="HBK3210893.1"
                     /translation="MHKMKKLVVRADDIGYSEGVTLGIISSYKNGIVTSAGIMVNMPF
                     SRQAIEMVKNDDVCFGLHVNLVIGEPCCKEHIKIKNLLDEGGKFVSSKIRRTQLLTGK
                     EVFNYEEVYEEVCAQIETYKLYMSKLPEYIDIHGIEEDVSISAMCDAAKEYGIPSCPY
                     YLDSCISMPSKYPQNDFYKLNKSFVKLFEEKYINLDKDITLMVTHPGFIDYSLIKSSS
                     LIQERVYEHAMLCDKEVKMWLKRNNIELVDFKDIFKSNNYI"
     gene            complement(99339..100766)
                     /locus_tag="KOU88_000989"
     CDS             complement(99339..100766)
                     /locus_tag="KOU88_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK3210894.1"
                     /translation="MMQQLSLLGKTMLVPIAVMPAAGILGLLFGPNMLNVPAISNISN
                     IVFSNVDYLFLLGAASAYSKSKDKTSVMVAAVVAYMIFKSNLELLNDTLNAGVFGGII
                     VGACIAWTYNKTYKVKVPAFLSFFAGEKCVITLSPVVALILSYIFSLLWIYPQAAMNQ
                     FGFWLGGAGAIGIFLFLFCNRALIPTGLHQVLNAYILFEMGEYTTSTGEVIRGEIPRF
                     MAGDPNAGFFWTGFYIIMMFSIPAISYAIYKTAQDKKKQEVKGAMTAGALTSFMATVT
                     EPIEFSFLFASPKLYIIHSFYSGLGGVVLYLLGARLGSFNGASIIDYVLSFSYGDKAW
                     LVIPVGVVFFVLYYVTFKYIIIKDNVQTPGREVEIEIGDKVSEKEKNLKLSHGNFSYM
                     AKQIIKNCGGYENIVTLNNCMTRLRLEVKDATILNDDNIKKTGAKGVIKLSNTSVQII
                     IGTDVVKVKDEMEMQLDELRKQADA"
     gene            101157..101879
                     /locus_tag="KOU88_000990"
     CDS             101157..101879
                     /locus_tag="KOU88_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3210895.1"
                     /translation="MAKNKFSEIYEVLKEEILDGKYTSNMMLPTELQLIERFSCSRNT
                     VRRAISQLNTEGYVQSIKGKGVVVLENSCSNDFFLNMHNFKGVESIVEDKKVNTATSV
                     LHFSKILIDNKLSKKTGFKVGSEVYYLHRLRYIDNIPKILDINYFLCSIVKDLDVSIA
                     QGSIYKYIEECLGTKIVSSRKIFKIEKATELELKTLPLNDYNCVGVIKNSVYTDDGKL
                     FEYTESKHTPETFVFMDVTQRY"
     gene            102076..103743
                     /locus_tag="KOU88_000991"
     CDS             102076..103743
                     /locus_tag="KOU88_000991"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBK3210896.1"
                     /translation="MKNWWKKATVYQIYPKSFKDSNNDGIGDINGIIEKLDYLYSLGV
                     DLLWLTPMYVSPQRDNGYDIEDYYNIDPKYGTMSDFEKLLKEAHKRDIKIMMDMVLNH
                     TSTEHKWFKESKKSKDNPYRDYYFWKDAKPDGSVPNNWISRFSGTAWKYDETTNQYYL
                     HLFEETQADLNWENEKVREECYKILEFWADKGIDGFRLDVVNLLSKTPGLPDDPITGP
                     KGDGRTHYADGPRIHEYLHNMNQKVFKPKNIVTVGEMSSTTPEECINYTRENREELSM
                     VFSFHHMKTDYKGGAKWTNEMFSLDKLKKAQSDFQYKMYEGKGWNALFYSNHDQPRAL
                     SRFGDDRFFRQESAKMLAITLFGLQGTTYIYQGEEIGMTNAYFTKIDEYDDAESKNAY
                     YHMIKSGIDEKEALLILQQKSRDNARTPMQWDNTIYKGFSNHKPWLKVNNDNISVENE
                     LNDSRSVFYTYQRLIKYRKQYDIFTEGTYRLLDENHKNLFVYEREYKNQNLLVISNFT
                     HDNVVYKLPETYLNKLNYTILETNYTRDIIENKMEIKPYESIMIYYK"
     gene            complement(103839..105158)
                     /locus_tag="KOU88_000992"
     CDS             complement(103839..105158)
                     /locus_tag="KOU88_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK3210897.1"
                     /translation="MEKGIKLGFWSIVLLGINAIIGSGIFGLPGDAYTDIGPASILVL
                     VFCMLLAVSIALCFAEAGSWFDTDGGPYLYAKEAFGDFVGFEVGFMKWIVSMIAWATM
                     ANFFAVTLSSVWPQAAEPLTKNIIIGILVVGLGIINFMGMKQSKHLNNIMTIGKLLPI
                     VLFIAVGLFFIKGSNFTPFVIIQKGQSASSAFVAVSITLFYAFTGFESLAVAAKDMEN
                     PKKNVPKALVMVMFVVSVIYMLILGISIGVLGNGLAGSATPVADAAIKMLGPIGGYII
                     TIGTIVSVGGINIASSIFTPRSAAALVEQGLMPKSIRKTNKNGAPYIAIIVSVIGTLL
                     IAWSGSFTTLSQISVVSRFIQYIPTCLAVLILRKKYAGKDVNFRIPGGAIIPIFAVII
                     SILLLIKAGIDEPMKIVWGLGGMIIVVPIYFYMTKVYSKKYNDVEVK"
     gene            complement(105199..105945)
                     /locus_tag="KOU88_000993"
     CDS             complement(105199..105945)
                     /locus_tag="KOU88_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBK3210898.1"
                     /translation="MKKLAKKKYPIIGISGNLLIDEGGMFPGYERAYVNNDYIQSVVM
                     CKAIPYIVPIVYDDEIIKEQVSNIDALILSGGQDVNPLIWKEEPHNKLGAISPKRDSF
                     DMKLLKHALDMKKPVLGICRGEQIINVTEGGSLYQDLSLIEGAYIKHNQQHLSNVPTH
                     TVQIKEGTKLYEILGEKEVLVNSFHHLVVNKVAPGYIVSATSKDGLIEAIEKEGSEFV
                     IGIQWHPEMMTRDYDNMKKIFMAIVKEASK"
     gene            complement(106189..108198)
                     /locus_tag="KOU88_000994"
     CDS             complement(106189..108198)
                     /locus_tag="KOU88_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3210899.1"
                     /translation="MKTIAVVTDGLSKLECFLNKNLEMIFKDKVMIKNYYLNKITEKE
                     LIKDDIILVMIDDRVLKIKKYVEDVSKIITINRSIKQKDIYKLFSLPEGIDVLVVNDN
                     KHTVLETISNLYNIGINHLNFIPYNPNEEYRNIKIAITPGESSLVPKYIEEVIDLGHR
                     YIDSSTFIQIIAKLKLDDKEITERLIKYTDEIISLYSGINTKYKELTIKADELNSIIN
                     LSNLGMAMVSDKRNIIICNNSLRDILDIQSNIIGKNIDELENENIKKIFSLSKAHDEV
                     IKFNNKYLNVNKYNIESFGRVTGYYFCIQEITYIRKLEQNLSKKLREKGQVARYTFDD
                     IKTVSTKMERTKKLGMKIAESDYTILITGESGTGKELMAQSIHNASPRHSQPFIAINC
                     AAMPENLLESELFGYEEGAFTGALKGGKKGLFEQANNGTIFLDEIGDMPIYLQSKLLR
                     VLQENQVMRVGGENVIDIDVRVIAATNKNLLEMIKGDRFRADLYYRINVLPINIPPLR
                     ERKEDIEVMLKHFMKRKRAISQDVQDIINAYEWPGNIRELKNTAMYINIMSSEDVILI
                     NDLPHNLLNITEDFSKEISILKDRTSIEKVKLVMECLKNANNLNKNIGRNGIVNSINE
                     LGYNITEGEVRGILNMLKELDLIICESGRKGSELNRRGKNILNSI"
     gene            complement(108636..110069)
                     /locus_tag="KOU88_000995"
     CDS             complement(108636..110069)
                     /locus_tag="KOU88_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK3210900.1"
                     /translation="MSFKKDFLWGGATAANQCEGAWNLDGKGPSCSDMCTGGSQKVSK
                     RITRVIEKGTFYPSHEAIDFYHRYKEDIALFAEMGFKVFRFSIAWTRIFPTGMEKEPN
                     EAGLKFYKNVIDECLKYNIEPLITISHYEIPFAITEKYNGWVSRDVIDLYMNYCETIF
                     KRYKGKVKYWLTFNEINSATMPMGGYLSQGILNEGTTDFINQVDIPQLRFQGLHHQFV
                     ASAKAVKLAHEIDSNYQVGCMQIFATMYPYTCNPDDAVKTQRDSRVMNYFCGDVQVRG
                     EYPTYMNRYFGENNIEIKMEKGDLEILKEGCVDFYAFSYYMSTCVSSDSKEDNTSGNI
                     LGGVKNPYLKSSEWGWQIDPEGLRYALNEIYDRYRIPMMVVENGLGAYDKKESNGVIN
                     DDYRIEYLKAHIEQMKEAVEDGVDLFGYTPWGCIDLVSASTGEMAKRYGFIYVDKYDD
                     GSGDLSRIKKKSFDWYKQVIESNGERL"
     gene            complement(110085..111509)
                     /gene="ascB"
                     /locus_tag="KOU88_000996"
     CDS             complement(110085..111509)
                     /gene="ascB"
                     /locus_tag="KOU88_000996"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK3210901.1"
                     /translation="MALRKDFLWGGATAANQCEGGYKEDGRGLANVDVTPQGKDRFPV
                     LAGKMKMFECDDEHYYPAHEAIDMYHNYKEDIKLFAEMGFKCYRMSIAWTRIFPTGVE
                     DVPNEEGLKFYEDLFDECLKYGIEPVVTICHFDVPMYLVKKYGAWRNRKLVDLYVKYC
                     EVIFTRFKGKVKYWLTFNEINMILHLPFIGAGLYIEEGENEEQIKYQAAHHQLVASAL
                     VTKLAHNINQEFKIGCMLAAGNTYPNTCNPLDIWKSIEKDRENYFFIDVQSRGEYPTY
                     ALKELERKGINIVMEEDDKKILKENTVDFISFSYYSSRLTSADPKVNILTEGNVFASL
                     KNPYLDASEWGWQIDPLGLRITMNSLYDRYQKPLFIVENGLGAVDNPDENGNINDDYR
                     IDYLRAHIKAMIDAVELDGVDLWGYTPWGCIDLVSASTGEMKKRYGFIYVDKDNDGNG
                     TLKRSKKKSFAWYKKVIESNGEEL"
     gene            complement(111596..113512)
                     /locus_tag="KOU88_000997"
     CDS             complement(111596..113512)
                     /locus_tag="KOU88_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3210902.1"
                     /translation="MRKYEQLSKEIIANVGGKDNISSLSHCITRLRFKLKDESIANDD
                     VLKKMDGIVTVMKSAGQYQVVIGNHVPDVYEVVCDLAGLGGDTIDNSDSDAPKGLLNK
                     FIDIISGVFQPILGVLCAAGMIKGFNAVFTALGLYGETDGAYIMLNAIGDAMFQYMPI
                     ILGYTAAKKFKLKPFIGMLIGAVLCYSGIQLDTLASTGQPLYNLFTGTIFESPVYITF
                     LGLPVIAMNYTSTVVPVILIVLLAAKLEKVFAKIIPDVVKNFFVPMAVLLVSLPLGFM
                     VIGPIATYASNIVGNGFLALFNFSPILCGALTGLLWQVLVIFGLHWGLVPIAMSNLMT
                     MGFDTILVGAFVPSFAQTAVVAAMYFKLKDKKIKELCIPAVISGICGVTEPAIYGITL
                     PRKTPFIYSCVGGGVAGAVMGIMNVKSYVMGGLGIFGIPNYINPTTGDMKGVYATIIA
                     IIVAIVVGFVLTLFFWKDDAIVEISKDDNGQGVIEKNKREVVYSPIKGEVKALEQIQD
                     AAFSTGILGKGVAITPKEGKVVAPFDGTVMTLFPTKHAIGIISDNGCELLIHIGLNTI
                     QLEGKYFKSFVNQGDKIKKGQTLITFDIESISKEGYCLETPVVVTNYSDYVDIVENTQ
                     KHVNNSQKLITVLA"
     gene            complement(113586..114446)
                     /locus_tag="KOU88_000998"
     CDS             complement(113586..114446)
                     /locus_tag="KOU88_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK3210903.1"
                     /translation="MIIEKILNNNVIITTDENHKEIVVMGRGLAYKKRTGEHISKDKI
                     DKIFKLSDPNISDKFKELIADIPIRYMELSDEIILYAKEKLGKRLNDSIYISLTDHMY
                     TAIERAREGVSVKNVLLWDIKRFYKSEFKIGLEALDYIEKKFEIRLSEDEAGFIALHI
                     VNAQMDQSIKTIYEITQIIQEISNMVKYHYRIVFDEDSVYYHRFITHLKYFAERIVSN
                     NLHENNEDDLLNVIKVKYKNAYKFIEKLDEFIHKKYNYDLTDEEKLYLTIHVERVVSK
                     SIKSDINPNN"
     gene            complement(114797..115984)
                     /locus_tag="KOU88_000999"
     CDS             complement(114797..115984)
                     /locus_tag="KOU88_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK3210904.1"
                     /translation="MIESIKKRAYEIENELGKEIEEVCNFIFNNPELGEEEYISSKYL
                     VEKMKEYGFDTVYPYCNMETAFRAELGDNDGPTIAFLAEYDALPGYGENKEPAHACGH
                     NWIAASTLGACIVLSKLKENFKGKIVLIGTPAEETTGGKCDLVKAGAFDDVDVSYQMH
                     IEAFNNINCKALAIDSLEFSFEGVSAHAASHPHMGVNALDAVQLTFAGINALRQHVKS
                     DVRIHGIVSNGGEAPNIVPEKAACKFFVRAAERSYLDEVTKKVINCAKGAELMTGAKL
                     SYRYFENSFDNIINNKVLQKITKNNLIEAGITDILEGKDGPVGSTDIGNVSQVCPTMY
                     TEIALDISPMVYVHEKEFLNYANSEEAYDKLHKAVKAMVGCALEIYLEDGLLDEIKKN
                     HLN"
     gene            complement(115998..117389)
                     /locus_tag="KOU88_001000"
     CDS             complement(115998..117389)
                     /locus_tag="KOU88_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBK3210905.1"
                     /translation="MSSLKKKKFTMPQTLTIIFLLIVLMAILTWIVPSGNFERVDIDG
                     RSVVVAGTYEKAPSNPQGITDVFTAPINGFIDAAEVVGFVLIVGGAFGIVNKTGAIEA
                     VIAHTVNKMKKFQFLIIPISMILFGLGGTTFGMSEETLPFYMIFIPLMTSMGYDSLTA
                     VATVFIGATAGFGAATTNPFSVGIAQALSQIVPGSGIEFRVVMFIIYMAISIGFVMMY
                     ANKVKKDPKKSLVHDISLNQELMVNSDTNIKEFTKREAMVIAIFTIGMAIMIYGVLRL
                     EWYITEIAMIFTAIGIISGIASGLKQDEIVNSFISGAGDLITAGLCIAFARGIVIIAE
                     NGFIIDTILNSAANLLNGLPKTIFINLTFLIEGLIAFLIPSASGLASLTIPVLAPLGD
                     LVDVSRQMIVTAYQFGIGVTNLITPTSGVLMGALAVANIPWSKWVRFVIPLMVVLTIL
                     VMAFLTIGLYLGF"
     gene            complement(117984..119684)
                     /locus_tag="KOU88_001001"
     CDS             complement(117984..119684)
                     /locus_tag="KOU88_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK3210906.1"
                     /translation="MHYIAWHFNKNGGNNTMKDKLQVLSGAMMIPVILLVVAGVFIGL
                     GSAFANMENVSALGLSGLIKEGSFINVFFKVINDLGFMVMRYLPIFFVTGIAFGLSKK
                     EKGWGALGGIVLFIGMHTVISTLLAANGINSDTVTAEAFMASGLGEAEAYSRSSLYGS
                     FLGIFSYDCSIFGAIIAGFVASAVHNKFVDIELPSALSFFSGPRFSMIMMFIASIVLG
                     TAMYFIWPPVGLALSKLGNWIGSSGLLGTFTFGAMDKALLPFGIHHLIAFPIEYTRVG
                     GTMEVGGAIYEGVNNIRLAQMGDPDTLSYITRNFTTGRLLIHFAILPAAALAMYKLAD
                     NANKKKAISILIPAIVTAMLVGVTEPIEYTFLFVAPLLYFVAYVPLAGLTYVFTEMFN
                     VSIMGESFRNMFPNLLQPQKVDALPLLFLIPIFFIVTYIIFTWAIKKFDIKTPGRSSE
                     EVKLYSKKEYRERQSVDAGKTAYNNAVEEEVDDKDTKLVHSIIEGLGGSNNIKNVTNC
                     ATRLRVELNSIDGFYEDGFWVNELGASGVVKKKNSVQVIFGPRVITIASKLKAVLGVD
                     "
     gene            complement(119656..121059)
                     /locus_tag="KOU88_001002"
     CDS             complement(119656..121059)
                     /locus_tag="KOU88_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK3210907.1"
                     /translation="MIVNKELIIDYLKSNQENIINDIRSLVEIPSIRDESTTDINQPF
                     GIEIRNAFDKLIQIAKDKDFVVKDFDGYAIHIEYGEGEEVVGVLNHIDVVPIYNKELW
                     KSKPFKVCQKDNYLYGRGVNDNKGPLIGILYALLFLRELNEKPKRKIRLIVGGAEETT
                     WECMEHYFSVNEQPKFAFSPDGNFPIVNGEKGILYFNLRKKIDKDKFRNHNLVDIKSN
                     KEDGFVCDKIEAVFKTNDKKDLVESLAYYTEIEELDEGKVLVRYTGERALSRNPHRSY
                     NCAFSLAKDLEKIKKLNDKGVIIRDILNSYFTDDNHGKKLGMYKEDVDMGVSTICIMS
                     IFLEKNELNMKIDFRYPKGISWEFITNRINEIGKKENLIVDIYKDLKLLYVKPDSELI
                     NKLSNAYKQGFGKEAELFTKGAASYARVLKNGVAFGPTIEGDNPNSHQANENISIDTL
                     YKAIEVYIYALYSLAFQ"
     gene            complement(121323..121814)
                     /locus_tag="KOU88_001003"
     CDS             complement(121323..121814)
                     /locus_tag="KOU88_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3210908.1"
                     /translation="MFNIFKKKENKIEKIYSPFKGNLVNLEDVPDAVFAQKMMGDGVA
                     IIPSEGKLYSPVDGEIVNVFDTKHAIMIKSNDNTNILIHVGLETMSLEGKPFDVKVKA
                     GDKVKAKDLIMEVDLDFITSNDLNIITPVVIMDDADSVKRTVKDRIEPGNVDINSIIM
                     EVE"
     gene            complement(121840..122652)
                     /locus_tag="KOU88_001004"
     CDS             complement(121840..122652)
                     /locus_tag="KOU88_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK3210909.1"
                     /translation="MRYKLICTDMDGTLMGKGFEVSEENIKALKEAMEKGIKVALVTG
                     RPYNAMKYFTSVLGDDIYIISTNGTYFKLLGYEYKKVLSKEALKKIYTIGEKYNLNKH
                     FKGCKIVISNNEIGEEHPYRLINSKNKEEDRIEIIENASCETLLEKADNEILKCILFS
                     ENVDSLREAKEEFKKQEDLEVVSSGKINFEVMSKGTSKGIAVKKFCDILGIDSKEVIC
                     IGDNENDISMIKFAGLGIAMGNATDEVKSMADFVTDTNVNDGVAKALRKILS"
     gene            complement(122665..123624)
                     /locus_tag="KOU88_001005"
                     /pseudo
     CDS             complement(122665..123624)
                     /locus_tag="KOU88_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
     gene            complement(123742..>124094)
                     /locus_tag="KOU88_001006"
     CDS             complement(123742..>124094)
                     /locus_tag="KOU88_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3210910.1"
                     /translation="TKLIKENDIICIEDLQVKNMIKNRKLSRSISDVSWSEFIRQLEY
                     KANWHGRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASIN
                     ILKEGLRLITIQNK"
BASE COUNT        38480 a        23642 c        15457 g        46515 t
ORIGIN      
        1 ttataattaa tatacttttt aatcaaattt aaacagaata attataccaa tatataaaaa
       61 aatttctaaa aaacaataaa attaagttat aaacaccaat atatttctat tatttcaata
      121 agtatacaat tagattagaa tctaacgcta gtaataaaaa attactttcc caaaatagat
      181 ataagcctca ttttatcgtt caaataatga aaatatattt gatttcatgc aaaaagagtg
      241 cctaatgaac taaaaagttc attttgagac actcattttt ttatataaat ttatatagtt
      301 tttaatcgtt ctcattcaac cactcagtta agacttttat atatttctca ttttcttcaa
      361 cgaatggcat atgtcttgaa tactcaaata attcccactt actattaggt attctatcat
      421 acatagtctt tgcaatatat ggtgaacata aatctattgc tccactagtt actagacaag
      481 gctcttttat ttcatgtaat ctatctgtaa attcatatcc agaaagagtt cctgtaggag
      541 aaaattcatt ttgtccccat cctacaatat atgcttcaga acctgatttt ttaggtcttc
      601 tcaggcactc tggagaatct tctgtcactt cacctgcaca atacatttcc ataaatcttt
      661 ctaatgcatc attatattct ttgctagagt aatctccagt atttactgca tcaagtaatg
      721 ctttttggtc agcctcactc atatatgata ttcttctttt ttgttctttc tcccaaagtt
      781 ttgcagaaga aagagtagat gaaaggatgt aagacttaat accttttggt ttatattcaa
      841 tagcatacca aatagcctgc atacctcccc aagattgacc taacagatga atttcatcaa
      901 gtcctagatg ttttcttagt tcaataagct cctctatcca agtatctgca ttaaatagct
      961 caggatgccc ttctacaaat gaatttccac aaccaatttg gtcatacatt attacttgtc
     1021 taccactttc agctatctta tccaatacct caaaatagtt gtgtgtagaa cctggacctc
     1081 catgaagtaa tactaatggc ttcttccctt ccgtattttc tcctactata cggtaatacg
     1141 ttttaaaacc tttaaaaggc atatatcctt cagtaatttt catgtttatc tcctccaatt
     1201 tgtaattata aacaataatc aagttcatta acaatactat ttaaaacctc ttatacatat
     1261 ttgattatgt attttaatct ttatacctac ttttataaat agtataacat aaaagttaaa
     1321 aatctctata ctaaaccaat tataaaatta tattaactat ataattttat tttttaataa
     1381 tagtatatac atatttgatt attttcattt gctgcttaaa atcaatttta agttttcttc
     1441 ctataataaa cttcctcttt gtggtctcat gttagtctct aaatttaaaa ttttacaaaa
     1501 aattttcata aaataaaatt atattgattg tatctaaaca aatagggcaa taaaataatt
     1561 aagtatagtt acttaccttt caagcaatat tagttttatg ttagaatttt attatattga
     1621 tttacaggag gtttgcattt gaataatatt aattcactta aagtaataaa attatctctt
     1681 ggatgttctc ttgctatatt tattgcttgg ctattaaaat tagaatattc aatggttgct
     1741 ggagttatag tactacttac agtaaaggac actaaaagag aaactcttaa aggctccatt
     1801 ggaaagattt atggttttct tttatgtact attttttcat atttatgttt taatatttta
     1861 ggatataatt tgacttcatt ttcaatattt atatttataa ttataccact ttgttttttg
     1921 ttaaatattc aagatgttat tgctatgtgt gtagtcatag catcccatta ctaccttcaa
     1981 ggagaaactt ctatcaaatg gattttaaat gaagctggaa tatttgcagt aggaactgga
     2041 ataggtgtct taataaatat gtatattcca acaaatatac ataaaatcca tgaagttcaa
     2101 aaaaagttac aggaagaagt gagtattgta cttatagaca ttgcagatat tattgtaaat
     2161 cctaaaaaag aaaatggata tagtagagat ttatatacat taaattcact tattgacagc
     2221 agtatttctg aaacttacga taatattaat aatactttat taagtgatac tagattcttc
     2281 ttagaacata tggatattat aaaaagccaa cgggatatct tagaaaattt gtatagttat
     2341 gtatctcaac taaattctac accaccacaa gctcatattc tatctgcttt tatacataag
     2401 ataggttata ctgaatttga agctgaaaca ggcaatcttc ttcttgaaga attaaagaga
     2461 ctaatgctta gtatgaaaaa ccagcctctg cctgttgaca gaacagagtt tgaaaataga
     2521 gctattttat tcctatgctt gactgagtta aaacagtttt tagttaatcg taaacatgct
     2581 cagatgctta gagataataa tttttataaa taaaaagggg agaaatctag cagttgacct
     2641 gactacaaaa tatcagatat aatattaaat gcgcccctag taagagggcg caatgtttat
     2701 aacttattct actgtcatga ttaaatcatt attcatatcg aacatacatt atttgaccaa
     2761 gtccaatatt agctttttca tcagtgattt ctattttaat agtcacatca ttttttttac
     2821 agtacttcgc taattctgca ccagaacgat ttttaccact aaaatctaaa gaaaatggct
     2881 tatcatattt aaaaggatat tcaacaggtt taccctctgg tgctaatgca aacatcccat
     2941 atggtgtgtt cataaatcct attacagcaa tcgtaagatt tgatgggtct aaatttgatt
     3001 cactacctgt aaatgtaatt gtatttactg atgaattaac tacactacat cgaacacctt
     3061 catacattac atgtttttca tttatatctt ctcctttttt tccaaaattt ccaacagcct
     3121 ttgccccttc ttgatgtggt aacatagtgt gcttcccagg tggtgctggt ttctgtgtct
     3181 gttctggttt taccgtctgt actattgcgc caacttttgg atatgctgtc ttatcaaatg
     3241 gtaatgggtg gctaagactc ttgtatatga tatcctttcc tgctgattta ttagcatcaa
     3301 tatctacatg atacaaacgc ccatcaccaa aacggataag attccactgg tggtcatttg
     3361 atgtgctgtg tacataataa gattcaattc ccatagcatc acacaaagct ttcatgctcc
     3421 tagccattcc tgagcatgca ccttttttag taaccaatgt ataggcagta tttgctccct
     3481 ctactgcatt ccagtcaaca tatgttgtgt tatttttaat gtgattgtag gcaactaaaa
     3541 tcttagcatc tgtggtcata ttctttgtga ttttcttgtt cataaaatct gctgttgctt
     3601 gtgctactga gtttagttgg gcttgtgaca gctttggacc atatacgcta ttggttccag
     3661 tgacatagct ttttggtgtt tttgctgtta cctctttggc tgtcatacca taaactgtca
     3721 tactcatacc tgagattaaa actattgttg taatcaataa cttggtagct aacttcctaa
     3781 ttttcttcat acttaatatt ctcctttata aaacattgtt acttcctatt ctctaccatt
     3841 aataaaatta atttaggatt taaaaaggtg gattgtcaac atgtatattt ctccattcat
     3901 acattcgtga aatatttaaa tttcatggaa aatctaatag atattttcta gataatttgt
     3961 atacaataca actcgcaaat cagggtgttt gctgttagtt tgagaaaatg atgatgatta
     4021 atacattcgg aatctttgac ctataataaa taccattgtc ttcaatcatt aataatggta
     4081 agagtaaaga gaattatcaa taatacagtt aaaatcaact ttgtatacat ttcatacatt
     4141 ctctcccaac aacattatac ttcttataat ttgtatattc aatacgtttt ctgggaaaat
     4201 atagatatat ctataaaaat ataaaaaagg agttgaactt aaaatttgat taaaaaaaat
     4261 caattttaag acaactcatt tgtattataa aaatgctata tattattatt aagtaagtca
     4321 atattttaga tatttatcta tttcttattg acttacgctt atagtctaac ttatttgttt
     4381 agttgatata taacctagtt ttaagcatta ttaatattta aataatcaag tatccttttt
     4441 gtttcttgta gtttctgttc tgcctcattt aagttttctt gaattataga aatatatatt
     4501 atatctatca acgtaagcat tgctattctt gaagaaatag ctccttctct aagccttttt
     4561 tctatatttg gtactactag ctttaaatca ctaatcttac taagatgatt gtcactatat
     4621 ttagttatac aaatgacctt acatcctttt aattttgcat tttctataga ctttattact
     4681 tcttttgatt ctccagagta agatattgct atagctatat cttctttatc tacatttgaa
     4741 gataccataa gttgtgtatg actatctaaa gaggtaaatg cctgtttatt tatccttaaa
     4801 agtttcatct gtaaatctag tgcaactaaa gccgaaccac ctactccaaa tatatataca
     4861 tttttagcct ttattatctg ttcaactgct tcttttatta tatctttttc attcaacaac
     4921 cttgtttggt tgatagtctc tatgtttttg tttgtaattt tgtttataac actatctata
     4981 ttacaatcat agttttcatc tacatatgtg tattcatttt ctttgcccat caaatcttta
     5041 gctatctcaa tttttaaatc cccaaaaccc gaatatccca tttttctaga aaacctaact
     5101 atacttgctg tacttgtttt tgagtttgac gccaattctg atacagaaag cttacttata
     5161 gcctctgtat tattaagtat gtaatcagct atttttttat ctacttccgt taaatcttca
     5221 tatatctgtt ttaattttaa aatgcaactc atactctatc acctctacct atttactata
     5281 atatttcttc ttagcaagta aacatgctcc taaatctgga gtcaacactg gtctcactat
     5341 accaaatctc gttttattca aatatttttt aagtggctct aatattaaat ctcctgactt
     5401 aaacactcca cctgaataag atacctttat ctttgtacct tgttcaaaat gatgctctaa
     5461 tcctattata agcctactta attcataagc tgcatcatca aatattttac tagcagtatt
     5521 atcaccttca ataactgctt ttaaacatat cgtagcaaac tttgctattt ctattctatc
     5581 tccttgtatt tcatcattta catattttat tatgtcataa tcattctcta tattaagatg
     5641 tctttttatt aaatcatata attttgtttt tgaacacctt ccatcagact gcattgtgaa
     5701 catttttaag gtagccattc ctatataata cgctgaacct tcatctccta atacatagcc
     5761 ccatcctcca catctgtgaa gattcccatc tttatctaaa gcctgtgcta ttgaaccagt
     5821 acctgcaatt atatttatac ctttttcccc atttaaagaa cctgctaatg ctatttctac
     5881 atcattacct agagtataat ttatatgact atatgcattt tttgttgcta cttctaatgc
     5941 atacaatact tcttttattt ttccatatcc agcaagtcca acaaatgcat acgttatttc
     6001 ttctacattt atcttagcat ctttacaaac ttcttccaac ccagttatta ataatttcgt
     6061 tagattatca aatcctattt gattataatg acaagttcct ttggttatgg ttcctactat
     6121 atttaattct tcatctacta atgtaaatgt tgttttcgtt cctccaccat ctacacctaa
     6181 aaaatacata ctatcctcct acaatatctt taataattct ttcaatactt aatatctaaa
     6241 aataaccttc caatgctgtt tttttaatat tgaaaggtta tcagtactat tatttatttt
     6301 acaatttttc tattgatttt aaagcttcac ttatataacc ttcttgtcta tctaggatac
     6361 tctttgcact atccttatct aaaccacttt ttatcataaa tatagccaat ttaacgctat
     6421 tatctgcttc ttctaagaat ttttctgcaa cgtcatattt tacatttgta gctatcatta
     6481 ttattctttt tgctctttca accaactttt catttgatgt cttaacatct accatcaagt
     6541 ttgagtatac ttttcccatc ttaaccatag aagctgttgt taacatatta cataccattt
     6601 tttgagctgt accacttttc attctagttg accccattat tacttctgcc cctactataa
     6661 tgtttattgg taaatccgct tttttactca tttcactatt cggattcata gttattgata
     6721 gtactgcaca ccccaattcc ttagcatact ccattgcacc tataacataa ggagtccttc
     6781 ctgatgcagc tataccacat ataacatcct tagatgtaac tcctctatct attatatctt
     6841 gctttccaag ttctttatca tcttcagcac cttctattgc tttaaatatt gcttgatttc
     6901 caccagctat tatagcttga acaagctcaa aatccactcc gtaagttgga ggacattctg
     6961 tggcatctag tattcctatc ctcccactgg tacctgctcc tatatagaat aatctacctc
     7021 cctgtttcat tctatctact attatattaa cagcttttgc tatactctcc ttttgttctt
     7081 caacagcata ggctacagtt ttatcttcgt tatttattaa ttctattatg cctaatgtat
     7141 cttctttatc tatttgcaat gtattcttat ttctaccttc tgtaactaaa ttttctaaag
     7201 tttttattaa catatcattt cctcattttc ttaatattaa atttttaaac acattttaat
     7261 tccaactttc ataattatat ttttataata aattaatatt ttcataataa attattttgt
     7321 tgagggttta aaattaaact tttgccatgg tttaatataa tctaatataa ataattcttc
     7381 ttttcttata tatcctacta cattcgattt accactgttt ttcatatcag tcaaggctat
     7441 ttgtaactcc cctgcataat gaccatattc actactttca attactatat ctcctctttt
     7501 tattatttta ggagtattaa atagttcaaa tttgtatcct ttatatttaa cacgagattg
     7561 agtagacctt atcagactat cagatatgtc ccctctatta aaatgtattt cttcaaagag
     7621 tatcttcttc tcaacttctc gtatattttc ctctattgct acatcaaatg taaccatatc
     7681 ttttctcata gaacctaata cctttagctc ctcatatgtt ggataacaat ttgatattat
     7741 tatatcattt atattattca tagctattat atgctttact tgaatatcta taggtagatt
     7801 tctgtgcatc tcaattgttg gaagcccatc agttacaggc catggtccaa atgtagtttc
     7861 attttgactt gttacaaaaa ctgctgttct taatccatac ttattaaatc tttctgtaca
     7921 ttttataaag tgttctaaat ttaatccact atatctatgt ggataaaagt tatgacatcc
     7981 tatcaaattt tctttatttg gttggtagtc cattattgta tctatataat tagtattatt
     8041 actcatattg atttctattt taagattttg aggattaaaa gtcattaatg cctcttcaga
     8101 acctgtaaat cccatatcaa gccttattcc gtctgccttc gtctttttaa aaaaattcaa
     8161 atctttgtag cttatttcta attcaccaaa tactctggga tttacatcaa gtattacctc
     8221 aaaaccttta aacttagcgt attcatttat acttttaaat tttttaatta tattttcttt
     8281 agtatcttta actgataata aacatgaaaa tatacgtgta aatccatttt cagcagcttt
     8341 atctatataa tcatatattt ccttagatgt tgttttttct ggataaattg atattcctaa
     8401 tcttcccatc tgtgtcatct ccttatatcc tatatgtgtt taaatttatt tcgaattaca
     8461 cgaaactttt ttaaaaattt gatgaaaaaa agtttcatat atatttataa aaaaagaaaa
     8521 gtttaccttt tcttttttta taaacaatca acaaaatatc ttcgttactt atttcataac
     8581 tgttatactt tgaaatttat actaatctaa tatagttttt aatttccaat atagtttcta
     8641 attaataagc ttcttgctct tcaacttttt cttcatgaag caacctctta tcgtacatct
     8701 tgacaaatgg atagtaaatt attattgata tagctataca taataagtta agaactgaag
     8761 ctctccaatc tccaccagtg gctaaatatg cccctactgg tcctggtaat gtccaaggag
     8821 cagtaactac tactctggat actaaattag cactcatagc aaaccatgaa actgttgcca
     8881 ttactattgg tgccacaaca aatggtatta ttaatattgg gtttaatact attggtgctc
     8941 caaatattat tggttcattt atattgaata ttgctggtat tacagttgct tttcctaaag
     9001 actttccata agctgatttt gctctaaatg caagaagtaa agctaagcct attgtagctc
     9061 cagaacctcc aatccatata aaccattgaa aaaagggttc agcagcaata cctggaactg
     9121 cttgacccgc agcatatgaa gctgtattag catctaataa ttgtatccat aaaggtcttg
     9181 ccaatgaacc tattattgat acaccatgta ttccaaatga ccaaaaaaac gttattaaaa
     9241 atattagtat aattactgat ggtaatgtgt cagtggctga aactaatgga gttactaatt
     9301 tagctatgaa gccatgccaa tcaaacccta ggaaataagt aacaatagcc attaaaatta
     9361 ttattaatgc ggctggtgtc agagcttcaa aagaccttgt gactgatgct ggaactgctt
     9421 ctggcatggt tatcttgaat ttagatttgt cagtaaatct ataaatctca acacctatta
     9481 tagatgttac aatagcaaca aacattgaac ctccaccaag attagccatt ggcatttgcc
     9541 atccttgagg aattgaatta taccaagcta aaagttctgg actcttttca actatcttta
     9601 ataaatcagg ggtaagaccc tctattgcag taggaactat tgtcaaaagg aatgtagctg
     9661 tagctaataa acctcctgtc aatccatcta acttatatga ctttgccaaa ctataaccta
     9721 tgccaaatgt agaatatact gatataataa aaaatgtcat tctatatggt agtaatattg
     9781 taactgcatt ttcctttaga tactgagtta ccccccatga atctggtaat ggaggaaatg
     9841 ctaatatcaa gaaaaatgac ccaactatta taagtggtaa tgaagctacg attccatctc
     9901 ttacagctct taagtgacgt tgttctgcca atctggccat agaagttgat aatttagtgt
     9961 ctaaaaattc tgtaaattta tctagcatct tttctctcct taattaatat ttatttttat
    10021 tatcattaaa atttttataa aattaacttt cttctaacct aacaacactg caactactat
    10081 ttactcaaca gctcttgaac ttgttttaat aactttggtc ctcctaatgg actataagct
    10141 tgtgcttgta ttaatgcaca tggtacacta acctcatcag caaaagcttt taaatagtca
    10201 aatctatgtc tgacttgtgg agctaccata gcaatatccc atccattttt aacttcatcc
    10261 tcaaactctt gagtaccaac agccaaaaca tctatatcta ttccattttt tgctccttct
    10321 ttttgtaatg cattaactgc tatagcactt gacatccctg atgaacaaac aaataatact
    10381 ctcatattga ttccccctgt ttttttattt cttttcaatc attatagcat gtatttttga
    10441 ttacaggaat acgtttgtat atattttttc atattttaca tttttatttg taattttatt
    10501 tcatgaattt atatcttgtt ttaattgctt tatttatcta atcattcttt tgtctaaaat
    10561 tacacactac ttaaaatact catatctttt cttaaaaaga aaaaagacta tcttattatt
    10621 aacataaaat agtctcaata cttttttaaa tatgtattcc tttatatatc cagaagtaac
    10681 ctattattgc aaatgataaa gcaaataaaa tatacagtct aaaaaatccc aaagaaaaac
    10741 ctctcttagt ttcaacaaag tatcttgtat atgcaactgc aaaagatgta attaatgaat
    10801 ttcctataac aactccaaat ctattatcta ttccaaatat agataataac aaaggaaaaa
    10861 ctacagtact tacaagagat gaaactatta gtattaatcc acttttaaaa cttatagttg
    10921 gaatattata atctgttctt tgatttttct ccatttgttt cttagtattt ttattacttt
    10981 ttgtactttt tgcattttta taattattat ttttctttct tttctttttt ttattattag
    11041 acatgtcatt tacctccaaa aggtttaggt gttatattcc ctaaaataac tttattttta
    11101 gcccctgttg cagatattac attagaaaaa gaattattta atgtttcatt gcccaagatt
    11161 acaaatgcca aagcctcctt tgcatcagaa gaatacccat attcatcttg tgttaatact
    11221 tcaacctcta ataataactc ttttatatat cctattaaag ttaaattatg agctcctcca
    11281 cctccaatta ataaagtatc tacattaacc tttgaaagta tgaagttttt ataattataa
    11341 tatatagctt ttgccgtaaa catagttact gttgctatca aatcatattt atctacatgt
    11401 ttatatttgt taagcatgtt atccaaatag acttgtccaa atacctctct tccagtgctt
    11461 ttaggtggtg cttgactaag atacttatga ctcatcaaat cttttaacat ttcttcatta
    11521 attttacctt ttgatgcaaa gtatccattt ttatcatact ttctattaaa taatctttga
    11581 catactccat ctattatcat atttcctggt cctgtatcaa atgcaaatac atcatctatg
    11641 ttacatgatt taggtattat agtaatattt cctattccac caatattttg aagtgctaaa
    11701 tttttattgt tatcactata taataaaaat tcactatatg gtactaatgg agcaccttct
    11761 ccacctgctg ctatatccat tactctaaaa ttagatatta cctttgtatt tgtttcatat
    11821 gctataactg ctggttcacc tatttgaagc gttgaagata caaaattatt ataacttctt
    11881 ggtatatgaa agattgtttg accatgagat gcgataaaat ccaaatttgc tatatgaaag
    11941 tttgctttat gacacactga ttttacagct ttactaaata aatatccaag cttaaaattt
    12001 aagctacaga ttaaatcaac actcgattcc tcttctatac agcactttct tatttcgtct
    12061 tttatatctt taggaatttc tagagttata aattctattt gcttaacttt agtatttcta
    12121 ccattcccac taatttcagc tagtactgca tcaactccat ctaaggaagt tcctgacatt
    12181 aaacctacac tatacatagt tatcatcctt ttaagtttat agttattcct ccccaaatca
    12241 aggtattaag tttaataatt ttagaattaa tcttatttca tctttaatta cgataattta
    12301 ctcttatgaa attaattgag ttaatcttat acacgttttt taccttagct aaatcttaca
    12361 ttaatttatt ttcagtgtca atgtaatacc atgtaatttt ttttcacaaa caaaatatat
    12421 tctctctcca aaaaccatat taaaatagtt actacaaata aaaaacatac caggtaccta
    12481 tctgatatgt ttttcatata taataattat tattttataa tatagataga gcatcattta
    12541 aggcactaat taaatcttca ctattttcaa gaactaaatt tattcttatt gtatatgtcg
    12601 atttgtatat gatgatagat tttatagtct aataacctaa ctatctaggc ttaaataatc
    12661 cgatatatca taaaagtaga tattaaaaat tgtatatgaa ccaattttcg aacatacctc
    12721 aatctcatgc cctaaactat ctatcatttt ctttacaaaa tacatcccca ttccagtaga
    12781 cttatacaat tgatttcttc catttttccc cgtaaatccc ttgtcaaaaa ccctagatat
    12841 atcttcctca tttataccta tgccaaaatc ttttatagat aataccactc cattttctaa
    12901 cttttttgaa ttaaattcaa tcttaccaac ttcctttgaa tactttatag cattattaat
    12961 aatttggtct aaaacatatg acatgcattt agaatctgtg taaacatcat tttctaattc
    13021 attcaaacta acttctacat tattttttat aagcaaaaat gaattatttt ttatagacat
    13081 ttttaccaat ttttctaaat taaatttatt tataaataca tcttcaaaca tagtgttgct
    13141 tctactacta tacaaaatag agtttactaa aaaatttatc tttgcaacct gattcttaat
    13201 atccaaacta tcttctatgc tacttaacct atctgtaatt atacttaaag aagatattgg
    13261 aatttttatt tcatgaaccc atttagctat gtactcatcc aattctttta atgattgttt
    13321 ataagtctct atgtcactat tattttttat ttttaagttt tctataatat cttttattag
    13381 attttcttca aaagattgtc cattaactaa ataactgtct atttcaccac tattttctat
    13441 acaattatat aaatttgtgt aactatttct aaaatttata taatctataa caaaaaatac
    13501 cattattata aacagtacta aaaaatctaa atatattaac tctgaatatt tatttttaaa
    13561 aatatctata gcaaataagt agatatttat tatactaact acaactaaag gtagagcaat
    13621 atacttagac ctacctttta aatattttac tagcattgta ttatatatcc tatccccttc
    13681 ttagttttta taaaatcatc aaaacctagt tctttaactt tacttctcaa tctattcata
    13741 tttacagtaa gtgcattgtc tgtcacaaac tcatcattat cccatagagt catcataaga
    13801 ctttcccttg atacaaccct attcttattt tttaataata atgttaaaat ttttatttcg
    13861 tttttagtca actctatact tttatcctta tacttatgtt ttataatccc tttccccaca
    13921 tcaaacatca aatcttcaca atacaaaata ctattagaat cactataatt atagactctt
    13981 cttattatac catttatttt ggtaaccaat atttctatag aaaatggttt ggtaatgtaa
    14041 tcatctgctc cattatttat acccattatt aaatccatat cagaatctct tgatgataaa
    14101 aatattaatg gtacatttga aatagctctt attttttcgc accagtaaaa tccattatat
    14161 aatggtaaat ttacatctaa aagtactaca tctggttttt tatctataaa ttcatctaat
    14221 actacctcaa aatcatcaat taattctact ttaaatcccc atttttcaag tgctaatgca
    14281 atctcttttg ataaatcaat atcgtcctct actaataaaa ttctatacat ttgtatattc
    14341 tccattatcc taatatttca ctatgctatg aattattaat atcataacat attttatatg
    14401 aatttattac ccaaattatt tagttaatca acaaggagac tcttattaca agaatctcct
    14461 ttctctttat taatatatca actaattttt atacactaca ctcttaaact tattaacaga
    14521 tactgctcca tatattatga atattatcaa acatatcact aaacttagta tatatatacc
    14581 aaataaatcg gtcatcaata aatctcctgc taatctcaat gcaaaataac tagatatagt
    14641 tgcacttaac attggcaaag tataaaaaat agctacttct ttaagtatag ctctatttat
    14701 atctttttct gtagtaccta tttttaacaa aatcttatat ttctctttat cttcatatgc
    14761 atcactatat attttcatat atattatact tccagctaca attgcaaaga ctaagaataa
    14821 aaacacaagc actacatatg caaacttcat ccattgactc tcaccttgag ctttatatcc
    14881 attttgaata tacccatttt ttaaacttaa attcttttca atattgttga acattacttg
    14941 actattttct tcttgaaata cctttgcacc ataaaaatac acttgttgac ccttatctct
    15001 tagtttaaaa tatgtatcat catttaccac tataatactt tgattaagtc ctgtccctag
    15061 tactggaact tttacttctc cccttgaaat attatataac tgaccatcaa gttttatctt
    15121 ggcttctttt gtagctattg atgctatcgt ttgagggctt tttaagtcta ttacattatt
    15181 tccactaact aatctttcat catactcttt taattcttta tcattgccat tcactttaag
    15241 agtattacaa aaatcactat atttcattat agtatctgtt gtatcataag cttcttttat
    15301 atctgttttc tttaaaattg ttagttctgg atttactgag tactttatct tattagtatc
    15361 ttttattata ttctctattt gttttttatt cacttcatct ttatccattg aaactatgct
    15421 aatagtgtac acatttcttt gttcttgggc attcttatgt atacgcttca tcgcaactga
    15481 agcaccaaga gttgatattg ttgtagttat aattatagct attatagcat aagttttata
    15541 gtttttattt aatcggtagt ttatattgtt tattgcaatt atattatttc cattaaataa
    15601 tattttttta tttttgatta taatatcaaa tataacaggc ataactgatt tgaataagcc
    15661 ataagtacct actattatta tacctataac aggtagtaca ctagttatat ttccagttct
    15721 tatattggta gaaagatagt agccatatcc tattactgta attgatatta tagctaatat
    15781 atatatacct attcctacct tcggtatttt ttcttgtttt ttagatatat tgattagatt
    15841 tattacacta cttctacata ttgttataaa accttttaca gccattatta taaatataga
    15901 aataaatatt aaagtagcat acagtatagc ttctatgcta agtccattag atacctttat
    15961 attaaatcca gataacttta ttatcattac ttgaaaaaat ctagatgtta ttatccctat
    16021 aattattcct gttatacaag agcttattcc tataagcata ttttctacaa aatatatttt
    16081 tcctatagta tataaatcta atcccataaa agacaatatt ccaatttctt tagacctatt
    16141 cttaaaaaat atatttgttg cataccatat aaagaaaaat aaaaatactg atagtatcat
    16201 tattacagct actaacactg atagtgtaaa ttttttattt tcctcttgta acatatttat
    16261 agcatcacca tatcttaata attcaaaatt agttagcaca actactgaaa aaaccataga
    16321 tataaaaaat gctagataag ttcttatgtt actcttaaaa ttattataag caattccaag
    16381 tatactcact tacatctcac ctcccataga ggctagcata tccataattt ttccataaaa
    16441 ttcttttcta ctatttcctt tgtttaattt acactttata tttccatcat ttatcatata
    16501 tacttcattt gaataacttg ctgttagagg gtcatgtgta atcattataa tagtagcgtt
    16561 attttctctg tttatttttt ctaatgattc taaaagttca tatgctgatt tagagtctaa
    16621 agcaccagtt ggctcatcag caaatatgac tgttggattt gtaattaatg acctagctgc
    16681 tgcgcctctt tgtttttgtc ctcctgataa ctgatatgga tatttatcta aatgattttc
    16741 taatccaaat tttttagcta tagaaaatac cttagcttct atctccttgc ttttcttttt
    16801 tcctaatgct aaaggaagtg ctatattgtc cattagtttc atattgtcta atagattata
    16861 gtcttgaaat ataaacccta ttttttctct tcttaatttt gatagttcat tattttttac
    16921 ttttgatata ttaattccat ctagtattat ttctcctgaa gtttgtttgt caagtgtaga
    16981 cattaaattt agcaatgttg tctttcctgc accagatgga cccattattg ctataaaatc
    17041 accttcattg actgtaagag atatattttt taatacattt gttttaaatc cttttattcc
    17101 ataatctttt gatatatttt ttatttttaa tatttctttc ataacaatag cctccagttg
    17161 ctaatttttt aatatatatt tattttaaag gttttatata aataaatcct taagtaaata
    17221 ttacatttta actgttagca ttacactttt gtaacatatg gaagactatt ataattatag
    17281 tagaaatatc ttaaaataaa agcatgattt acttctttgt ataaacaaag aaaagaagct
    17341 cctaagaagc ctctaatcta tacaattatt cttctctata aaaaaccaaa atacaaccct
    17401 gattgtggca aatacaggta ctataaacaa gtgatattac tgctatatat taaaacaatt
    17461 attactgaag ataattcaat aagactatca agccataagc taagcatcca aaaagactta
    17521 ataccattaa tgtataatta tacccaatat taatgctcaa aaaaccagca acagttggaa
    17581 taatcagaga tgaacctccc ataaatatac ttaaagctat taattggcta ctacttctaa
    17641 gttttttagg agaaacttca aatattaatc tttttgaagt aattaaaatt aaaggagtag
    17701 aaaacacttg aaaaacacac agtataataa tgatatttga atcatttgtt aatgcaaata
    17761 atagaaactg aactgttatc ataatagcac ttaactttaa taagtttaaa ctgctatatt
    17821 tttttaataa ataagaacca gccagatatg ttggtatctc taataatgac tgtaaagacc
    17881 actttaaaga tatctgagaa tttgtagcat ttaaagctat cattttatct attacagtac
    17941 agttatttgc tactaccatt gagtataata agaataaaat acatactagt aagatatatt
    18001 ttttatcttt taataattca ataatatctt tattagttac atttattttc ttattaatct
    18061 tttcaatatc aggtaataat agtagattta taataagtaa tactacaatt aaaccaatcg
    18121 ctacagataa tccaaaatat gagaatctaa gaatcaagta agatgctacc atacttccaa
    18181 tagcccatcc aatcgaccca aaagtcttaa taaatgacaa ataattatta atattatctc
    18241 cacaacctat tatccatgta tcatataaac tacagcaagt atttaataat cctcctgata
    18301 aagcaacaag taataagtat attataaaag ttgcagattc agtagaaaac ataataactg
    18361 atgcaattcc ataaactgat aaactaatta aaacaatttt tttcattgtt tgatacttat
    18421 cagctaatac tccaaataat aattgaaata atatattggt tattgcataa ctcgataata
    18481 taattcctct ttcaaacgct gagtaaccca attttgataa gaaaggtgtg aattttgttg
    18541 aagcaaaggc aaaaataata tatgagaaaa aatagaatat gataaattta aatttaatcg
    18601 ctttattaat cataatcaat caaaattgat aactttaata ccactatttc cttcctgatt
    18661 taagtttgaa agatgatatt ttaccgtatt aggattctct acaataacta aaggaatata
    18721 taaagtattt tcaagtaact tattatcaat ttctactaac ttttccccca tattaacttc
    18781 ttgaccttgt ttaacttcta atttaaagtt ttcttttttt gttgttgcac tatccaatcc
    18841 aatatgaata agaatttgaa catcattttg caatttaatt cctatagcat ggttagtttg
    18901 agcaataaaa cttattactc ctttagtcgg tgatttaaga atattgtcct ttgctatcat
    18961 agcaaatcca tctcccatta ccttagttga aaatacttta tcaggaattt ctccaagatt
    19021 aattattttt ccatcaatgt atgaattaat tgtaattgct tctttttttc ttttaaagaa
    19081 cattatagac actcctctac ataattaact ttattctaat tatcattaca aataacgata
    19141 ttaagcatac tgcaattgag gaaaaaagag ccttatagct ctttccccat tgtagttctt
    19201 taatactgct tatgatttgt ctaattccaa caaatttata aatataggta aacatgataa
    19261 caatagttat tgtgtaaatt tggaatatct gccctaataa gactaaatag aaagcaatca
    19321 tgttttcttt tatctcttta ttctttttta tattgtaaat aacatatgca ctgtatactg
    19381 cactaaagtt agagattaaa tttaaacttg cattaacatc attgtttaaa agttgtgaaa
    19441 atgaaatatt tgtaaataat gatgtcaatt ctaaatacac tatatataaa acaggtaata
    19501 ttagaaaaca aaccataacc actgaaagaa atatattttc atcttttaat actgctgtga
    19561 tattttttat tttatttgtt atcatgtttt tgttctcctt atttaaaagt tggccagaaa
    19621 tccttattag ccacaatcat ttcatctaag atttcttttg ctacttttgc acttggaaca
    19681 gttttactca tagtaaacga ctgccataat ttttgataac ttttttctat ccatgcttct
    19741 acagctaatt tttcagaagc aacttgttgt tccattaaac ctttttggaa agttggaatt
    19801 ttacctatag acataggttc aaccatatct tttccaacaa ggcaaggaat ttcaaccatt
    19861 gcatcatctg caaaattttc aatagctcca ttattaggaa caatcagtaa aaatctttcc
    19921 tgagtattaa atgctaatgc acaagctaat tcaacaataa attgagaatg ttcacttgca
    19981 tcaaaccatg tatctcttgc tgtgccattt tttataattc tttcacattc ttcgaatgta
    20041 tccttttctc ttctatccat aatttcattt gctcttgtat aatttggatt agcatgttca
    20101 acagtttcat cagccattaa ataatatttt aaataagtat taggtaatgt agtcggttct
    20161 atttccaata aatcctttgc tgctctcata gtttctaacc aactagattc tttgtgttga
    20221 ccttgaggtg taaattcctc atatcctttt ttagcacaat attcttgtaa tttaggcatt
    20281 aaatcatttc cttctttgtc cttaatactt gtccaccacc cgaaatgatt caatccataa
    20341 tatctaacat caaagtcttt acgagaattt aaacctaaaa ctctagcaaa tatttcctct
    20401 aaacatactg gcatatcaca aatattaata attcttgaat ttggtcttaa tacacgacat
    20461 gcttctgcaa ctatagctgc tggatttgaa taattaagca tccaagcatt tggagaatat
    20521 ttttccatat aatcaatcat ttcgattatt ggacctattg ttcttaatcc ataggcaatt
    20581 ccacctgccc cacaagtttc ttgaccaaca accccatatt ttagtggaat tttttcatct
    20641 tgttcacgta aagcatataa accaacacga atttgtgcca ttacaaaatc aatatcagta
    20701 aatgcttctt ctggatttgt tgtataacta aatttaattt ctggattttt ctctctaaca
    20761 attattgcac atgcttcagc aacttttctt tgtctctcat cattattatc atataattta
    20821 attgattcaa taggaaattt agcaacactt tcaattaaca ttgttacaat tccagcagta
    20881 taagtactac ccccaccagc aattagtatc ctctgtcttt ttctttccat ctttccttct
    20941 cctttataat aaattttcaa attcttctct tacacttggt actgaaagcc caataataat
    21001 ctgaatagct tttccattat gcactaaacc atgtgcacct actgccttaa aatcttcttc
    21061 tttagaaata attgagtcat ctttcaaggt taatctcaac ctcgtagcac agtttgtaac
    21121 atctacaaca ttttctgctc caccaactaa ttttatgtat tcagatgctt gttgagaggc
    21181 tttactcaat ttatttcctt tttcatcttt agtttctaag tattcatttt tagtatatag
    21241 ttttgtttct tcactatctt cttctctacc aggagttttc atatcaaact tcttaattaa
    21301 gaaagtaaat acaaagaacc agataaatga aaatataatc cctacaacaa cttgaacaac
    21361 atataccttc cagtgataca ttccaagagg aagccaattt aatacaaccc agttaataat
    21421 tcctccacca aaatcaccaa caactcctaa ggcaaacgaa atcgtttgca agcacgcatc
    21481 taaaaatgca tgtactagga ataaaagtgg tgctacaaat aaaaatgtaa attctaacgg
    21541 ctcagtaatt ccagttaata ctgcagtaag agtagcagga atcattaaac ctaatacttt
    21601 tttctttttt tctggctttg cagttacata gaaagcacca aatacaccta atgaaccaaa
    21661 caccttcgat aatccggata atgaaaatcc gattggatac atttccttta gagtcttagc
    21721 tgaagtttga aagtcctgaa tatgagtagc ccaatatact gatgtaccac ctggaacaac
    21781 aacactatca taacaaattg gtgcatatac aaaatgatgt aatccagttg gtattaaaat
    21841 cttttgtaag aatgcataac accaaactcc tatatttcca ctatttataa aaaacgtttg
    21901 caaatgtcta ataacatttt gaatatgagg ccaaataaaa caagttaata atgcaactgg
    21961 tatcataaca aagaaacaaa ttgcaactac aagtgatgag cctctaaata atccaataaa
    22021 atctggtagt tctttatcat aaaatctatt atgaatataa atgacaatac ctgatattaa
    22081 caaagcacca accataccag tatctaatgt tttaatacca gcaatgctta caagtccact
    22141 tccagcactt atttcagctg cgaaatcaac tccaaagctt tttccccaaa aacttaacat
    22201 agaacctaca aaataattaa aagtcaaata cgttgctaaa gcctccatac aagctcttgc
    22261 ttgttgcttt tttgcaagtg ctattggtaa agaaatagca aataataatg gtaattgatt
    22321 aaataccatc caagctccac tagatattac accccaaaat tggtaccaaa tattttctgg
    22381 tgtagcaagt gaacccataa ttgactgatt ttgaaataca attgagaatc caaccattat
    22441 cccagcaaaa gcaaataata gtgttggtgt aaacattgcc cctccaaaac gttgtatttt
    22501 cttcatcata taaattactc ccctcctcat atttttagtt tatctttggc cttagatatc
    22561 tattatttta acaggttaat aaatatatac aatctttagg gtacattcgg agcttattca
    22621 cagtcaaata agtttttgca catttttatg ttcaaattct cataaaaaaa agaatgacta
    22681 caatttgcaa tcaatccctt ctgtaatcat tctatgcctt ttataaatac tatatttaat
    22741 aaataataac tcaatcaata taaaatataa cattgtcaat ttataactag ggtgcatttg
    22801 caaaaatgag atattagtcg ctgaaatata aattgattca tcacttaaat cagtcaatgt
    22861 attattttta aactctgtaa ttgaaattat tttagttcct attaatttta atcttctagc
    22921 aatattaagt gtattctcat tctcaccact tagagatata ataatcataa catcattttt
    22981 actgacaata ttgtaaaaag aatcatcaaa tgttcttccc tcaaaatcat atattatttc
    23041 ttgacatgat aagaacattc tctttatctg ttttgcaacc acattttgaa tatcacctga
    23101 accataagcg tatattgttc ttgattcata aagaagttta cacaatgcat cataatcttt
    23161 atttttttga tcttcaacat acttaattat tgaattacat gcaatatcaa atgactgatt
    23221 ttctatgaca tgaacctttt ctgattccca gcttaataat actttaaact cactgaaacc
    23281 ttttaaatct aattttttaa caaatcttgt aatagttgca cgagacacat tacatttcat
    23341 agcaagttca tttattgaca tcttactaca atgtttttta tttgcagtta tatatttcca
    23401 tattaataaa tctgtatcat tcaatttatt ataatttaaa aaaatcattt cttctaatct
    23461 cataaactat tacccccttt aattaaaaat cgtcataaat attataccaa tattcaacat
    23521 taaattacag cgtattctta tatttactat ttagcccata aaattgacta taaaaaatac
    23581 tgctataatt gatgtttaaa aaaatgtagt tttaatttta ttcttttatc taataattaa
    23641 tattttcaag ttctagtgct tttcttatac aattatcatc tttaaaatca gcagtccttt
    23701 tacaatcttt tactttaaat tctggaatag ttttaaattc ctcatcacat attccattct
    23761 tatttaaata catacaactt gccattctaa ctattagacc actatttttt aaattaaaca
    23821 atacagggtc tatacaccct ccatctccgc cagtagtttc accaactaaa gtcgcaaatt
    23881 tattttcttt acaaaacatt gcaaatgact ctgatgatga atatattttt ctatcaacaa
    23941 gtaagtatat attaccctta aattttgaat catctgtaga ttttatagta taggaagtat
    24001 cttcaaaatc attaaaatct tttataattt ctttaggtgc attttccttt acacttgctg
    24061 gtaaattttc tacaggattt aattttatat ttcttgcatt tgtatatttt tttactattt
    24121 cattattatt tctataaatt ctataaccat ttattttgac atcatttttt atgagtttag
    24181 atacgattcc ctgccaataa ctatcacttc cacctaaatt acctcttata tcaataatta
    24241 aagctttatg tttttctaaa gtgttaatat aatctccaat tatttttaaa tcattattta
    24301 tagagccatt ctttgatgac attgatggta aatacatata tccaatctga cccttaataa
    24361 catcctttaa aattaattct ttttttacaa aaatatcatc tggcattttt attttaagat
    24421 tcatagagtc atatctatcc acaacttttt tatcattaag aaaatcatac caaccattat
    24481 tagagtatga tttcttaaaa agttcatatc ttttcttatt atctattact tctgtgtgtt
    24541 tattatttaa atcagataat atagatgaca gttcttctat aaattcttca tcattttcag
    24601 tgttttttat tcgttttgta tattcatcct tatttgctaa ccaatcaata ttattaagcc
    24661 tcttatttac acctagatat ggatatcctg tctttacaac attatacaca taattaaagt
    24721 catccacctt ttcctcttca gacaactgat tcttttgaga ataagtagaa ttacctaata
    24781 agattataaa tgctaaaata attactaaaa ataatacttt ctttttcatg taattctcat
    24841 ccactttcag attttatatt ttaatacatt gtatcattat tttattatca cctaaacagt
    24901 taaaagaaat tcttgaagat atattccact attattctat ttaaaaattt ttatttgtat
    24961 tttcaaaatt atttcatgaa agttataaaa taacaattat attcaaatat ctattttact
    25021 gctatatcct gaaagtaaat tcttatcagt gatatactaa aaaagatatg ctaaaaaatt
    25081 tatccattat aatgacttaa atttatatac tttactgatt tttatttatt agttgagaaa
    25141 tatattgata attaaaaata ttgataacta tagaaatgat tattttttat agaaatttta
    25201 aggatataaa ctaattatac ttaagtctat atccttaatt tatcatgatt atgagaattt
    25261 ttacaaatac ttatctttgt ccgttttaga ataaaaacaa gaacatatcc tgttatttta
    25321 tttaaacatc caagtttaat tactacacaa ttacttatta gaaattgtat ctacttcata
    25381 tatatatctg ttaagtatag cttctagcat ttcttgtctt ccagacttat tctttataac
    25441 tggcatttgc agtgcataag attctaactc tttaaatcca accttacctt ctactatatc
    25501 cttacctata ccttcactaa aacttgcata tctttcttta gtaaagtttt caaatacctc
    25561 atcttctaat aatttatgag ctattaataa tccctttgca aatgtatcca ttcctgcaat
    25621 ataagctagg aataagtctt ctacctcaaa agatgctctt cttactttag agtcaaagtt
    25681 aaatcctcct ggtgctattc caccttgctt taacacttca tacatagcaa gtgttgcatc
    25741 atatatattt gttggaaatt ggtctgtatc ccaacctaat aataggtctc cttgatttgc
    25801 atctatacta cctaaaacat tgtttattct tgatatattt aattcatgtt ggaaagtatg
    25861 tcctgcaagt gttgcatggt ttgcttctat attcattttg aagtatttat ccagattata
    25921 ctttcttaaa aatcctaaaa cagtagcagt atcaaaatcg tattgatgtt tagtaggctc
    25981 ttttggctta ggctctatta agaattgtcc agtgaatcct atttccttag cataatctac
    26041 agccatttgt aagaatcttg caaagttatc catttcaagt tctgtattag tgttaagtaa
    26101 agtttcataa ccttctcttc caccccagaa tacaaaattt tctcctccta agtacttagt
    26161 tatttccata gcttttttaa cctgagctgc tgcatatgca tatacatctg cattacatgt
    26221 tgtagatgca ccatgaacaa atcttggatt tccaaacata ttggcagttc cccataataa
    26281 ctttatacct gtcttttcca tattaacttt tatatactca actatttcat ctaatatctt
    26341 atttgtctct tctaaatctc ttccttctgg tgctatatct ctgtcatgaa aacagaaata
    26401 ctcaattccc atcttagaca taaattcaaa tcctgcatca actttaatct ttgctatctc
    26461 aattgggtct gttatattat tccaaggtct ctctactgtc cctactccaa atgggtcatt
    26521 accctctcca cataaagtat gccaatagct cattgcaaat cttaagtgtt ctttcatagt
    26581 cttattacct accacttgtt caggattgta gtatctaaat gctaattcat tgtcagattt
    26641 tactccttca aattttatct gtcctattcc tttaaatatt tcactcattt catgtcctcc
    26701 taatatttta cacatataat atatgtagta tgttttctta atttaaaact attttctatc
    26761 tttatttttc tttttaagct aatttaatta tttatttttg cattaactac ttcatctaat
    26821 aacttaaagt catctttcaa agatttgtat attcttttat acaatctatg atatatattg
    26881 tatgtatcta cattttcact tattggttct aatttagttg aagtttttat tatagcatca
    26941 catgcttttt gtatattttc atatattcca gctcctacta atgcaagaat tgcaactcca
    27001 agtgctggtc cttcacttga atttatagta tatacatctt gattaaacat atctgcttgc
    27061 atctgtctcc atactttact ttttccacct ccacctgagg ctcttacttc attaacgtct
    27121 atattaagat tctctattat atccatacag tctttaagac tatatgaaac accttccatt
    27181 attgaccttg caatttcttt tttagaatgg attggagata atccaaagaa cacacctctt
    27241 gcataagggt caagatgagg agttctttct cccatcatat atggtaagta aagcaatcca
    27301 ttacatcctg ttggtacttg acttacttga ttatttataa tctcatatac atcttcacct
    27361 aaagaatttg aaacttccac ttcactttga cagaaattat ctttaaacca ttttaatgac
    27421 aagccagctc cttgagtaac tcccataaca tgccatgtat ttggtattgc atgacagaaa
    27481 gtatgaactc taccttcttt atcaattttt ggctcttttg tataagcaaa tactacacct
    27541 gatgtaccta tagtagatga aactactcca tctttaacta ttccatttcc tatagctcct
    27601 gctgcttggt ctccagctcc tcctaccact attgttcctt ctttaagccc tgtcaaactt
    27661 gctacatctc tagtcacata acctgtaatc tcttgtgatt cataaacttt acctaaaaga
    27721 tttttatcta tatttaactt ttctagtact tcatcgctcc aatctctttt tcttatatcg
    27781 agcaactgca taccacttgc atctgatacc tctgtagcat attcacctgt caatttgtat
    27841 cttatataat cttttggaag aagtatttta ttagtatttt tatatatatc tggttcattg
    27901 tttctaaccc ataatatctt tgatgctgta aatcctgtaa gtgctggatt agcagttatt
    27961 tcaatcagtc tttcttcacc tactaaatca gttatctcct cacactcttt tactgttcgt
    28021 tggtcacacc atattataga gtttctcaat gttttacctt cattgtccag cataactaga
    28081 ccatgcatct gtcctgataa tccaattcct tttatacatt cactgcttat atttgaactt
    28141 tgaactactt ctcttataga ttcgactaca gctttccacc aatcatttgc atcctgctct
    28201 gcccaacctg atttctcttg tataagagga tattcatatg tacaactttt tatagtattt
    28261 cctagtttat caaataaaac tgttttcgta cctgatgtac caatatccac acctaataca
    28321 tactccaact tcatccctcc ttgaatgcca cttcataact atcgttttcc tatcctaatt
    28381 tttttatatt ttaggtatat tttacttgct ttatttttgt tagtatatta aactaactta
    28441 tgaactaata ataaaatatt taattatctt tgtcaatgca aaataacctt ttatttttgt
    28501 gtaaaaagta ttacaatatt attttaagga ggaatatcaa attggttact gataaataca
    28561 ctattcgaga aatgaatgaa agattggtac ttgaacaaat tataaaaaat ggtcctattt
    28621 ctagggcaag tatagcttct actataggat tgaataaagc aactatatcc gctattacca
    28681 aaaaacttat tgatgaatct ctagttcatg aaatcggaat tggaaatagt actcatagtg
    28741 gcggaagaaa acccatatta ttagtattta ataaatgtgc agggatttct ttaagtatgg
    28801 acattggata cgactatata ttttcttctc tatcttactt agatggaact attataaatt
    28861 ctaagaaatt aacagatata caagtaagta aagacaatgt tatacaattg atagatgaaa
    28921 ttataaatag ttataacata tccaaaatag acactcctta taaggtaatt ggtcttactt
    28981 tggctataca tgggattact tgtgaaaata aagtattgtt tactccatat tacaatctta
    29041 atgagattga cttatatagc atccttagca aaaagtatga ctttcctatt cacatagaaa
    29101 atgaagcaaa cttaacagct ttagctgaga atactttttc aactgtacat aactcactac
    29161 ttagtctcag tattcacagt ggatttggtt caggcattat aataaataat aaattatata
    29221 gtggcagaaa tggtatgagt ggagaaattg gtcacactat catcatgcct aatggtaaac
    29281 tatgtccttg tggaaatcgt ggctgtttag aacagtattg ttcagaaaaa aaggtatttg
    29341 aacagctttc ttctttagaa aatattccta aaatagattc tgatatagta aagcaactat
    29401 attatgaaga taaccagaat gccaaaaaag ttattcatga gttttgtagt tacttaacaa
    29461 tagctataaa taatgctatt acaacttatg ctcctgaaat aatatattta aatagccaaa
    29521 taattagtga tatccctgag atattacaga ttacaaaaga tatgttagtt agctctttta
    29581 acaaaggaat aaatatagaa atttcatcat tagggtctga ggcatctcta tatggtggct
    29641 ctgccgtaaa tatcaagagc tttttgaata tacaaaattt aactttaatt aatgaaatat
    29701 aagggttatg actatataca gccataaccc tttaaattat acattctaaa attagattta
    29761 ttatatagtt tatgcaagat tagctatatt ttttaaaaat tgtatatcaa ttaagtatta
    29821 acataagtat ttcgttttaa atattaatat aatcttccta ctcatcatca gataataaac
    29881 ttgcattttg ttcaaccata gaaatattat ctttacctat tttctctaat tttgctgcca
    29941 attcctttgt atctaaaaaa gctgattcaa taaccatacc taaatttagc cctgaaataa
    30001 ttttaattcg actgtcatta ttggctacta ataaagcagc attgcatgga gttccaccta
    30061 gtaaatctgc cattataatt atttctgaac tttccttgta cacttctaaa gcttttttta
    30121 atttttctat tgttccttct attccatcat cttgtttcat atttacagta ggataatcta
    30181 tagaatcccc tattatcatt tttgcagaat ttaagacttc ttcagccata ttgccatgac
    30241 tcatcaaaat aatactattc aatttaatac acctctttaa atctataaga tgtctacaag
    30301 ataagttttc ttatcatcag gcgtcattat agttgtaatt tcaattcctt catctaaaag
    30361 tcttttaaat gcttctttct cttcttcagt aacactgata ttaggtctta gaactgttgt
    30421 atcttttcta cttgacatat ttcctacatt tatattatgt attttaaatc ctgcctctac
    30481 aaatggaata aggtccacag gagacttaac aattaataat acattttgtc cttcatactt
    30541 tcctgcagta atatttttta tagcagtctc ttctgtaatt atagatgacg ctatacctgc
    30601 aggtgtagcc attcttaaaa cttgtttttg aacagaattg ttagctactg catcatttac
    30661 taccattaat cttgtaacac ccaatttatt actccacata gttgcaactt gaccatggat
    30721 taaacggtca tctatacgaa tatttttaat acctttcatt tccatatcta atatcatcct
    30781 ttccttattt taaaatacct aatgcatata aaattattga aacaaccatt actcctaaaa
    30841 ttaagtatat aggttttata ttctttttaa gagcccaata aacaatcaca actagaattg
    30901 caggaactaa cccaggcata atttggtcta atatttcttg acctttcatt gtaaaatcac
    30961 cttgttgaaa gttcaaagca acattagctt ttacaactga aggtattaat gcacctacaa
    31021 ccattaaacc taaaatagat gtactctcag ttaaaatctt taaacttttt tcaattgaag
    31081 atattagctt agtacctgat gtataaccag cattaaatag tggtatactt aataatttca
    31141 atgctacact cactacaatc cacagtaaga ttccaaatgg acttccatct atcgccatat
    31201 tagctgctat agctccaaaa attgtccacg gaataacgac aaataaacta tctcctaaac
    31261 ctgctactgg tcccatcaag cctgttttaa ttgaagcaac agcctcttca gtctcttcac
    31321 ttgataactc ctccattgct acattaatac ccaaaatata aggggcaacc caaggattag
    31381 tgttaaaaaa ttgtaaatga tttaatacag cactttgtaa cttttctgga ttatctttgt
    31441 atactacttt taaaaaaggt agtactgcat aacagtatgc caaggcctgc atcttctcat
    31501 aatttgaaga aacagaacta gtaaaaaacc agcgccataa gacacttttt ttcacctttt
    31561 catttgattt atttaatgat accttatcac tcatcttcgt ccatacctcc tactacagta
    31621 tattgttgtt cttgattttc caaattcttt ttgtaaatta taagtgcaat tgctccacca
    31681 attaaagcta cacctaataa tggtactttc atatatactg ctaaaacaaa accaattact
    31741 aagtaactaa aatactcctt agcaggaaga tatctaagta ataatcctat ccctactgct
    31801 ggaagtagtc ctccagctac tgttaaacca cctgttaacc attcaggtgt atatttcaaa
    31861 atggtattaa ttaaagaagg tccaaatatt acagatagag caactggaat acctgttgta
    31921 gctgctgtta atagtactcc taacatttgc atataggtta tatttttata atttcctttt
    31981 ttagctccat cttctgcttt atgaactagc catataccaa tagtatttct aagaacatct
    32041 aattgtacca tcaataaagc aactggaata cctatagaga ttcctacaga tgcttcttgc
    32101 ttagtcgtaa tagttataaa tgtggctact atacttgctg tttgataatc aggtattgat
    32161 gctccaccaa agttactaat acctaatgat aatagctgta atgtacctcc aatatataac
    32221 cctgtattta tatctcctaa gataagacca gtaataaaac ctgctgttac tggttgatat
    32281 gttccaaaca ttgttgaatt tttttcatag tttataaaaa atccatatag tacgattaat
    32341 aataattgcc ataattgtgg ctccattatg atttcacctc tcccaaaata ttttttagtt
    32401 ctttaaaatt ataactggaa tcttgcttta ggaaaatagg aatttcttcc agtgggcatt
    32461 caacttcata agttttccca ccttcataac taactccact aaatatattt tcccatgtat
    32521 gtccttttgg taaatatact tttctacttc tatctttata attcattatt ggagctacta
    32581 aaatttcatc tccaagcata tatgtattat ccacctccca agttttatca tcttcaggaa
    32641 attcataaaa taaagttctc ataactggtg ttccatcttc atgcgcttct ttcatcagtt
    32701 tttttaaata agtttttaag ctctctctaa tttttatgaa ttttgtaaga attacttcaa
    32761 cttcttcacc ataagaccat atttcattag gagctccagt taccattgag cctccacctt
    32821 tatttgataa tggtttacta tgaggcaatc tatctccatg cattctcaaa attggtgaaa
    32881 aagtagcata ttggaaccat cttaccataa gttctctaaa ttctgggtct ttaggatttc
    32941 ctccatggaa acctccaata tcagtagtcc accatggtat acctgccagt cccatattta
    33001 accctgtatt tacttgatta ttaaaagctt caaaactaga atcaatgtca ccagaccata
    33061 ctaaagctcc atacttttga gctcctgccc aagctcctct tacaagagtt acaacagact
    33121 ctatgtcatt atgtaaacca tcataaatca tttttaaata atcaatagga taaatattac
    33181 cacaacttaa aacatttcct tttttatatc tatagttatc aaaatcatac acagaatagc
    33241 caggttcagc tacatctaac caataatagt caatcccaag ttgtttataa tttttatcta
    33301 ttctatccca aacatattct cttgcatttt catttgtcat atctacaaag actgtatttc
    33361 cttgaatttg cattgtcatt ctaacaccac gattaacatt gactaaatag ccattttcta
    33421 aataatcatt gtagttttct gcatcacttt gaactgtagg ccatacagat actattggtt
    33481 ctactgaata ctcttctttc aattttttaa ctaattcttt aggatttttc caataatcta
    33541 agtcaaattt atattcacct tgcttaggcc aatgaaaata gtcaattgca attgatgaaa
    33601 gcttaattcc tcttttagaa tattccttca caacatctaa aacttcttct gaagttctat
    33661 atcttagttt actttgccat agtcctaaaa ggttttcagg catcatagga acagttccag
    33721 taacttgaga ataattttta tttaactctt ttgggctttc tccacaagta atccaataat
    33781 ctataaaatt tgtagaaaac atcttccatt ctgtcatatt tttagcaaaa gatacttttc
    33841 caattcccgg attattccat aaaagtccat aacctagact agaaatataa aaaggaactg
    33901 atatttgaga atttctttgg gctaactcca aaacagtatt ctttaaatct aaaaatttat
    33961 gttgatattg tcccattcca aaaatctttt cagagggctc agattcaaat ctagtagtta
    34021 cttcaaattc tccactatag cttggtcgat attctcttga ttttaacttt agagtagagt
    34081 taaagtcttt ggtaatctca attgtcccta catcttctcc accatcatca tgttttacag
    34141 ctcttaatcg aatatattct ttcaataata tttcattttt atcattataa aaagtaattc
    34201 tatctctatg gtctaagaca gcttttatct ttccattttt aatgattgca cttccatctt
    34261 catttttatt aattgtaata tcatctttat ttaacttagg tttttcgtta agagcatagt
    34321 tttcatcaac aaaattttgg tctacaaacg acctaatacg taaagagttt tttccccatg
    34381 cttctattcg caatagttca ttgtcaaatc ttttttcaat atagtcttca gatattttta
    34441 tcacggctac ctcctaaatc aatggtataa tattctatct ttgtgtagct taagttaaat
    34501 aatgtcgttt agtatcgtta tttataaatt aggttttata tataattcat ttgtacatta
    34561 aactaactta ccaataatat actttatttg actttgtttg tcaatcgctt tccggatttt
    34621 agtaaaattt tctaatatgt tgcttgaaag tcgttcttaa tatcttttat ttatactttt
    34681 aatatctgtg atgataccta tatacatcta gtttttttaa aacacataca ggaataacgt
    34741 ttgcctatta tgtagataat atcggacttg aaaatatgta tagtgacctt ataaatacag
    34801 ataataatat attagatatt gttcaaaaca atggatttta taattataaa taatttatga
    34861 aattatttaa taaaatatat aattgtatac caagtcaaaa acgacaacaa ataaataaaa
    34921 ctaaaaaaga tgttgtctca aaatatagat aaatttattt ttcattgcta aaatgattaa
    34981 aatatatttg atttaatata cttgatttaa tataaaaaaa agagtgtctc ataaactaaa
    35041 aagttcactt ttagacactc ctttatatat attatctact tcttaattca tttattacct
    35101 ctctacattt tctttcaact agtggataca tctttataag tactaattac tccacttaaa
    35161 aatgattcag gtactgtcca tcagtcatat ttttctgcca aatataatgg tgtttcataa
    35221 tgagacaata aatatttata tctctactta tcttctctaa gctcgtcaaa tccaactata
    35281 ggtatattta aattatattc tttaagtagc ttttctagct cttctataaa aatacctttc
    35341 ccatccacca tttgtatatc ctttatttta tccatcaatt cattgcaacc acttaactca
    35401 ccaaaccaac gtttagaact acatgtctta ttataaccac aacttggact gccatctatt
    35461 gcaatgatac tttttatatc ataatcattt tttaaatatt catcaaactg ccttacatga
    35521 ggtattaaca tttgcctaca ttgttctcta aaaaacaaat tgtcaaactg ttcttttaca
    35581 tgtccccacc tatttattcc atacataatc atttctgggc atggtagttg aattattcca
    35641 taccctttat ttattaaatt tatcgctata ttttgtgctc ccttaaattc tgacaatccc
    35701 tccactttag aattacaatt taatatacaa tgacatacta ctacaatctc tctatttctt
    35761 ttcataataa tctccttagt tattcttaat tttaatgata ctacatattt tgataattat
    35821 attatttatt tgttctatat ttccaatatt ctatatagaa atatacaatt agtaatcttt
    35881 tataatctat actatgataa atgtatatat ttttttagga ggtattataa ttggatacta
    35941 aaaaagtcac attttcttca atgtgcatag ttattaatat tgtcttaggt atggttatat
    36001 ctatgataaa tataccatta ttatttttag atacagttgg tactgtactt ggggctgtcg
    36061 tattaggtcc tttttggggt gctcttattg gtgggtgtac aaacttagtt ttaggtgtta
    36121 tatcaggtcc tacaaatata ccttttgccc ttgtaaatat tgttcttggt cttattgttg
    36181 gatatatttc taagaaaaaa ggttttggtt ataaagaagc tattattaca ggagtaattt
    36241 tatctattgt ttgtccttta attggtactc ctatttcagt tttattgttt ggtggtttaa
    36301 gtggaagtgg tgctgattta ttggttggtt ttttagttca gtctggtcag aagatattta
    36361 ctgctgcgtt ctttccaagg attcttagta atatagtaga caaacctttg tcttgtatta
    36421 tggtggtata ttttataagt aaaatgccta aaggttttat aaaacaatat agtaaaaata
    36481 cttctagttc atattaataa atcatttatt atgtaaggtt tattactctt taaaatgcta
    36541 tatactcatt tttatataac atttttatta ataatttaat tagatagtat ttgtattact
    36601 ttaattaaac gtaacctctt gatataaatt tgagctataa atctatatca agaggtgcta
    36661 ttttattttt aatataatta atattctatt acgcaaaaaa tgcatatatt tcattatttt
    36721 atggaaaata ttacttcatt taactctata tcaaactcat taagtaaaaa tctaattata
    36781 tttaatttag cctctgtatt taaatttgtt tctaaatata tattttctga tattttaata
    36841 ccttttctta atttatatgc atctctagac ttaatattat ctataaaatc tcttttataa
    36901 gttttgtcta caatactcag aatccaaatc atataaagta agagcaactt gttcataaaa
    36961 ttctgtccaa tttttagcct tatatgactc tcctaatata ctaaatgata ctatactttc
    37021 atttgtaaaa ttaacatcat catcctctaa cgtaaatata ttttcactgt tacttggagg
    37081 ttcatatgta acacttggat atttccaaat ttctacagct ctatctagta atatcttagt
    37141 tctatttttt atttcttctt cattccactt atctatagat aaaatatatt tatttagata
    37201 aagcctacta tctttaaatc catcttccat ttctttcttt tcttcaaatg ttttattact
    37261 tagttttgaa ttatatcctg tcaaagttaa atttccaatt gtatgtaaat atttatcatg
    37321 tatctcctta tagttatctc ctagtgattc cttccattta tttgttaatg tctgtggcat
    37381 tatatgctct atatttagca tattattatt gattaaattt tctaaatcaa caatttcttt
    37441 attattataa ttctctaacc tctcaagtat atataactta ttctttgact tagtattata
    37501 tatatcttta gtttcaaaag catttgaaaa ttcactgtca gtaggaaatc tttgagatga
    37561 tttcttattt ataaaaatat atcttaatat attagaatag ttttctttat aatcactaaa
    37621 ttttttaatt tcccttccta agttcataaa tactttattc agtgcattcg gaggtacatc
    37681 acatactatt cttcttaata taaaacattc tactaaatta agggattcta caagtacttt
    37741 tttatttatt ataccttcat tataatcatc aaataattct aatataaacg gatatgatac
    37801 aaatatttca agtttgttta tccttttcaa aactttgttt acatcattat catcagtaca
    37861 tgaataagat atctctctat aatagttaga aaatttaagt aaatctttta ataaaatttc
    37921 tatatctata ccattatctg atacatacct tttaaaacta aaatatactt tatttttatt
    37981 cggtatactt ctctccttta tagtcaaata gtctcttata aaactactta cgttgctact
    38041 tgtatttttt tcaattttat accaataatt attataaaat tcctcttgta acttagagct
    38101 tctacccatt aacacaaagt ttcttactct atcagcttca cttaaatcta agccagttga
    38161 atttagactt tcaaagatta attgagggtc atcttcacca ttttttaact ctatttctac
    38221 tatagttaat ttctgtatag catcaaacaa atcatctatt gatatattat cttcttttat
    38281 tctattataa aaatataaat aatttgaaac tatattagaa tttctatctg tattcatttc
    38341 ttcttcaaat agttcatagt acgcttttct atcttctgct attggtttta actttatttt
    38401 tccatcttta tctcttgagt gcttgtttat aagataacac tccttaatct gttcttctgt
    38461 tgtaataatt ccttttgatt ccccaaactc ttttattatt tgacacatgg caatcaataa
    38521 tattgacaca gtagtcactc tttgttgtcc atctattatt aaatattctt ttcccatact
    38581 atatatagat acaactgacc ctaagaaatg agttctaaat ccagaatcta ttatatcctc
    38641 taaatcatca aacaatcttt tacattgttc tttcttccag ttataatttc tttgatatac
    38701 aggcactaca aaacttttgt ttgacccctc taaataacta agaaattcaa tttctcctgc
    38761 tttcatatta actcccccta taagttaaat aaattccatt cataactcca tgtatctata
    38821 tattatatca aaattttgac tcataaatgt atatgaaagc cttattatat acctttttat
    38881 acctattttt attttattaa agtaaataca tgattattct ataaaatata caaatactta
    38941 attttaaaaa ttattattta atcttcttca tgagtaattc atagttattt atcaattaaa
    39001 aagagatatt gcataattat tcaatacctc tctttgtata tttacattat ccatatctag
    39061 ttatctattt caacccaata ttagactacc tactaataaa tttattctct acatcattaa
    39121 caataatttt tcactaaata acatcattag cctatctctg atgcattttc tttaatttta
    39181 tttatagttt taatcaattt atttctctct tcaatatgat tttcaaataa atcaattata
    39241 cttccaacag ttctaaatgg gtcttccatc aacactttgt tatcctctat aaatccattc
    39301 ttgactacat aatcgactat aagtttaaca aaatgtattt gcttagtatt aaagctctta
    39361 ttatttaaaa actctgaaaa agcttcattt gcagcttctc tatccaatcc cactagtttt
    39421 ctcactaatt gacttactgg agtatctcca aactccttct tataatcatc acaattacct
    39481 aactgtttta agagtatttc ctccaacgtt tcaacatctt gctttgttat ctttttatta
    39541 tttcttaatt taaatattgc taattcatct ttatggctat ttaaataata ctctaccttc
    39601 tttttataat tcttaagatt gtttgcatta tatacagaat catttctatc ttctgctaca
    39661 atcatatctt caaaacttgt ataatatatc ttttgactag acttttcaag atacttaata
    39721 agctctctta atgatatacg tacttcttct acctcaaata tatctgaatc ttcccaaaaa
    39781 tcctctgtca ttgctttttc aatagtatat ttttgttgct gaatctgtgg tatagtccca
    39841 agttttgaaa gtttttctgc tgtagccatt acatgcctta tacctttact tgcattatta
    39901 ttttgtaagt atgcaagttg tatattatac ataactacat caaatctttt agccaattca
    39961 tcatcactat atgaagttat gagtggtgat atatattctc ttatctcatt ttgtgctact
    40021 gctccaatat tgctccaaac attttcattt ttatacttat gtacataact taaattcatc
    40081 ctaactatat aactatcctc atttaaagct tttacagaag ttataagttc ttctaacaat
    40141 tcttttctaa gttctgcata ctcaccttct atatatttaa tatcttgaag ttctttaacc
    40201 atacttacct ttatattaaa taatttttca gtaagtgttt ctgttttatt tccctcaaat
    40261 cctttaggat taaatttaaa aaattcaaaa ttattacaaa aatcaaatat taagaatctt
    40321 tccttatcca tatcaacacc taataaatct ggacataatc tagttcctct acctatcatt
    40381 tgccaaaact tagtcttact tctcactttc ttgaaaaaaa caagatttag tatttcaggt
    40441 atgtcaattc ctgtatcaag catatctact gaaactgcta tttgaggtaa tttattctta
    40501 tcagaaaaat catctattat agaatctaca taatttatac tatagtcaac tgcttttaca
    40561 aagttcccac catactttgg atacagttta ttaaatcttt caactattgc cctagcatgc
    40621 tttgtattct ttgcaaaaat tatagtctta ccaatctttt cttctccttc tattttcaac
    40681 ccctctgtca ttagcttatt taaaactaaa tctattgtgt cagaattaaa tagccactca
    40741 tttactgcat tattccctat ttcgtctcca atactctcat catcattaaa tgtattttca
    40801 tattcttcct tctcttcatc agaaagctca tcatacttaa ttccatcttc cataatctta
    40861 gtcttaaact caatactagt ataatctact aaatatccat cctcgactgc cttattatac
    40921 tcataagcat atgtaggtac tccattttcc atgtcaaaaa ctgaataagt atttttatct
    40981 atctcatcct ttggtgtagc agtaagaccc attaagtaag aatcaaaata atcaaagatt
    41041 gacttatact ttttataaat acttctatgc gattcatcta ttataattaa atcaaaatga
    41101 ccaggtgtaa acaatctctt tccatcctta gacttcgtat catcaattgc attcatcatt
    41161 gttggatatg tagaaaatat catcctagca tcttctgggc tatctttgct atccaataaa
    41221 ttacataacg ccaagttagg taatagctta gtaaaacttt ttttagcttg ctttaccaat
    41281 gcttttctat ctgctagaaa taatatattt ttaatccaat tatgtcttga aagtacatca
    41341 actatagata tagcaattct tgtttttcct gtaccagtag cacataccaa aagagttttg
    41401 cgttgcttat tttcaagagc ctcacataca gccctaatag cttctttttg ataatatcta
    41461 ttggatattt catcatttat tgttacagaa gttaaagact tcttactctt tcttctatct
    41521 atcataagtt gtaattctga ttttttataa aatccataaa ctttcctatc tgaatagtca
    41581 tcccaaatat acatatcaaa accattagtc aaaaatatta ccggtctttg actatatctc
    41641 ttttccaaac aatctgcata taatttagct tgttgttgac caattttcgg gtctttactc
    41701 gttcttttcg cctcaactac tgctaatggc ttaccatttt caccataaag aacataatct
    41761 acatatccta caccactttc attaggcata ccttgtactt ctatttcttc ccatatatct
    41821 tttccaaatt cccaacctgc aagctttaat tctatattta tatatctttt tcttgtctca
    41881 aattcgctta cttcgtctat cttgaaatca tagtttgcag tattaacttt tctcttttca
    41941 gttagtgact ttcttaattc ctcattttct tttattactt cttcaagctt tttatctttt
    42001 gaacttaatc tctcataaag atttttaagt tcgtctggtc tcgtcctttt ctcttcccca
    42061 tgaagtaata aatcttcatt aaagtcttct gctgtatatt catctgaata acaatagtct
    42121 atccaactaa caaattgatg caaattgtta agtgaaagta ttgcttctcc tctctctatg
    42181 ttcgcactag tatgtacaga taaattacct aatttaacta tatattttaa taaaggtaac
    42241 atatcatagt ctataagttc tataaaacta ttattatgaa tcaacgtact aagattatct
    42301 tgataaggca ataataaatc actatcatta gtatatagcc attttactgc aagctctaaa
    42361 gctcttcttg ttatagttgc acaagtagat gggctaacta gtatactttt ttctgcttct
    42421 aagcaagcag tattaaaact attgaaattt ttcttctttt gtaaaaaatc aaaattaccc
    42481 aaggcttttc tccccctttt gtcccttagt taaaataaat ctctctaaaa actatttctt
    42541 acagctgttt cttatactaa caaatacttc ttcattttct gtaaacaatt cgtacatatc
    42601 ttcaaactgt ggtatatcat atccatgaga atcatcattt ctcaattttc taagtgtttc
    42661 tataactata gaagaatttt taggtaataa attgtgatac tcacaagtta aaaggtggtc
    42721 ataaaagttt ttagatttta tatttaaatc aattgattta taatacaaca ttgcttttgt
    42781 taattctaga aatgatacca tatagctttt aaagccttct tttatgtatc tagcccataa
    42841 ctcaggcatt tcttccttat catataagat tttgaagttt tgcaggtcat acaagcaaga
    42901 accaaaatcc ctatttactt cttctattga gttccaagat aatttgtttc taattaccat
    42961 acatgtccct ccaatctaag atatctatta catcactgtt ttcaaaatag aatttattta
    43021 tataatcctt aaaatcttta gattcataaa taacttcacc ttctaaaata gcttttttaa
    43081 gtgctattgt ataattatct gtaacaattt ttaggtctac atcaatgtct aatatatttc
    43141 ttagagcttt tgtcttagtt gcaagttctg taattggtac ttttttgata ggaatccaag
    43201 ctatgtctat atcactttct gatgtatgtt tatctgttcc ataactacca aatattatga
    43261 ttgctagagt attttctttt ggaaatacat ttattattga gtttttaatc tcatttggta
    43321 tatttctcat ttaatcacct cttgtttatt aggtaatatt gcttaattga atttatatcc
    43381 ataatctttt aatctattta tacatatttc tctttcttca tcagtaaaca actctttata
    43441 cttttctttt aatactaata cttctaatga taaatctaat ctcttacact cccatagcct
    43501 tgtaaatcct tcagtagctc cttctttatt gattaattct ttagcagcta ataaggctcc
    43561 tttgttattt atcagttgta aaaatcttgt tggcttatag ttacattgta aatcagcttc
    43621 tttatagata tttaccatgt catgatataa atctagctct atttgattca tagattttat
    43681 tcccccattt taatacttgt attttagttg aataactctc ctttaaaagc tttttgcatt
    43741 aatgagttaa agttgttttc tagttctttt aagctatctt ccattcttga tttcaatttg
    43801 tctatttgtc tgacaaagtc cacaaactta ttttgaagat atacaggtac tttaggtatt
    43861 tcaacttcat ttaatttgcc tactgtaaga cctggttgtg ctgctccagt tgataatcga
    43921 tttaaatcta actctttaag tgtaaaatat agccagtaac tatttatatc aactttaggt
    43981 tgtactacaa ctgcatgttc tgtagcataa aactttccat ttacatattt tacattacca
    44041 cataatgctc cttgcctacc tatgagatta aatgttccct tatgtgaata catttttaca
    44101 tatcccctta aaccatttcc tccataacaa ggatataatt catgtgaatt tttttcataa
    44161 atatcttttg cttttatatt ttttccagct tttaagtttg atatctctcc taataactct
    44221 gtatcccaat ctttactatt agtaatcaca tttccaaaca tctcaataaa tcttgattta
    44281 actaattcat ccaatgcttc tatttgctct tttcttttat ttattaactc ttgagcttta
    44341 tttaaaactt ttaccatttt attttgtata caaattgtga aatatggtat ttttatatca
    44401 tttaacttgc ttttatttaa agttgcaccc ataactgctc tatcagtatt attaaaattt
    44461 aaagttctca aagcataata taaatattca gatgttataa gttcattatt ttttatttga
    44521 aagttagcaa ttgcttcatt tgtaaacatg tcttctttta atatggcaac tctacctata
    44581 gacaacttaa aactcattac aacggtattt ttaggtacta atttcatatt agctttttca
    44641 acagctaaat ctgttatctc ttcttttgat tttgatatat atttttcttt caaatcagaa
    44701 attgataacc atctattacc acttccccaa taatcagaag tatttctaga tggtgttttg
    44761 ccaatattta tatagcacaa ttcatttaat tttatatact ccatacccta tacctctaac
    44821 attctttcta attcttctaa tccaacagct atttccttct ctaactccct aactctacct
    44881 ataatcacac taggagcatc ataaactact tcctcataca ctacctcttt atacttatta
    44941 atagataaat catacccatt ctctcttatc tcttccacat caacaaaaaa gctttgctct
    45001 gttctttttc tatctacttc accatcaaga ttatcaaatc tcttaataat atcctctata
    45061 tcactatcct ttatctcatt tctcttatca tccaaagaat aaccatcagc tttcatatca
    45121 tagaaccata ccttatcagt tccacctgtt cctgttttag taaatatcat tatagctgta
    45181 gatactcctg cataaggctt aaacactcca cttggcattg atattatagc ttccaattta
    45241 tgattatcaa ctatttcttt tcttatcgat ttatgtccac ctgttgaacc aaacaatact
    45301 ccatctggca ctatacatgc gcatcttcca ccaattttta aaactcttaa aaaaagtgcc
    45361 aagaataata actctgtttt ctttgtctta gtcactttta ataaatctgc tgacactgct
    45421 tcataatcta aacttccctt aaaaggagga tttgctaaca ccaatgtaaa cttatcttta
    45481 tctgtattaa cctccgataa agaatcctta tactctatat taggattgtc aacgccatgc
    45541 aacatcatat tcatagcacc tattctaagc atagttctat ccatatcaaa tccatagaac
    45601 ataccattat taaaatgctc cttcagccct tgcactaaga aaagacttga atgattatcc
    45661 cttaagtatt gttgtgatga tactaaaaaa cctgctgaac ctgctgccgg gtctactata
    45721 atatcttctg gtgttggttt aataagtctt actatcatat ctattatgtg tcttggagtc
    45781 ctaaattgac cattagtacc tgctgtagcc actttggata ataaatactc atacaaatct
    45841 ccctttgtat ctctatcctt acttaattct aaattactaa taccatcaac tattttagat
    45901 aacataagag gtgtaggaat tttaaatatt gcatctccca tgtactttgc ataagctgag
    45961 tctttatttc catgtaattt ttttatgaaa ggaaacactt cattttgtac tatttcatac
    46021 attttttctg aatttccttc attagaaaac ttactccatc ttaaatgttg atgttcatca
    46081 tcaaatatcc tttcaaaaga aactcccaaa agagttgctt ctgcttcatt ttttgtttct
    46141 acttcatcca atcctttaat aaataaaaga tatgtaaatt gttctataac ttctaatgga
    46201 ttagttaatc caccagtcca aaatgtctcc caaatcttgt ctactttgct ccttaattct
    46261 cctgtaatca tatatgactt tccctccagt gttcataaaa taatttaaat atatatttta
    46321 gtcgtacgcc ttaataatta gtgtcttata ttaaattcaa aattttacta cacagttatt
    46381 aaattatttt tcctatttac atgttttagt taaaaaacta atgcaatact cttattttat
    46441 gattattata catcccatac aaaattattt tatcatatat ccagcataga agtcatctac
    46501 ctggataact cttaccatat tataactttt taatattaat ttaaacttag aaagaaattt
    46561 tttatttaat tatatcatct tccttatttc aaatttctca attacaatct caatcaaaaa
    46621 ataaaataag atgctgtctc aaaatagata taatcttctt ttttattttc ggaatgatga
    46681 aaatatattt aatttcatac aaaaaagagt gcctcctgaa ctaaaaagtt cattttgaga
    46741 caccccttaa tttaatctta cttattctct ccctttatta ttaacacttc actatctcta
    46801 ttgcttttcc tacacatcca caaacttcca tcctactctt aacaaaatct ttaactgact
    46861 ctaaaccttt tttaccatat ttcttagggt caattacctc tgggtcagaa ttaagcacat
    46921 ccttaacccc attgctataa gcaatcctta attcagttgc ataattaacc ttgcaaatcc
    46981 ctctttttat agattcctta ataacttcat ctggtattcc agacccacca tgtaatacta
    47041 atggaactga tacaacatct ctaatttcag ataatctatc taaatcaagc tttggctctc
    47101 ccttatataa tccatgtgcc gtacctattg ctactgctaa agatgatacc cctgttctct
    47161 ctacaaactc ttttgcttct aatgggtctg tatatgctcc cccatcacca ccatctaaat
    47221 cgtcttcctt acctccaact ttacctaatt cagcttcaac aggtatatct gaaggcatac
    47281 atgcatctac aacagattta gatattgaaa tattatcttc ataactttca tgagaaccat
    47341 caatcataat agaagtatat ccaactctaa gtgcctgcat agctagtcca aagcttgaac
    47401 catggtctaa gtgcattgct actggaacac ttgccttctc tgatgctacc tttacattcg
    47461 ctaaataata atctagtcct gcatacttta ttgttgaagg tgttgtttgc aatattactg
    47521 gtgatttaag ttcttcagca gcctctatta ctgccataac catctccata ttttcaacat
    47581 taaatgcacc tactgcataa tgcccttctt gtgcatctaa taatatttgt ttagttgtca
    47641 ctaatgccat aatttctcct cctatatgtt tatactgatt tgatttcttc gttatttaat
    47701 tttgatacta tttctctact tgttttgcta tttaataact catttaaaaa ttcttcattc
    47761 attaattttg aagatagttg agataatgtt tttaagtgta aattatcacc attatctgta
    47821 gctgctatca taaatataat atgtgctaag cttccatctt ctgattcaaa gtcaaaccct
    47881 tcttttgata cacctactgc tacacgtggt acctttactg catctgtttt tgcatgtggt
    47941 atcgctatcc ccataccaaa acctgtagat gatatttctt ctcttttaag gatttcttct
    48001 ttaaacttct ttttatctaa aagaacacca gatttatcaa gtattccaat catttcatca
    48061 attacatctg ttttattttt tcccttaaca tctaaaatta ctgtttcttc gctatataaa
    48121 gagatattat tagatacgtt ttccgattct gcactttcat ttttatgttc atcttttgtt
    48181 acatttgtat tttctatagt atttttctca tttactactt taggtgtaac catcatataa
    48241 agtacagcac ctactaatga acctacaaat atacacccta cccataaaag tggcttattg
    48301 actaatccta gaaccaaaaa ccctccatgt ggagctggta cttctatttt cattatataa
    48361 gttaaaattg atgatattga tgatgcaatc ataagtactg gcaacacttt taatggattt
    48421 tttgctgcaa aaggtattgc cccctctgtt atatgagtac tacctagtat ataattgatt
    48481 aatcctgctg ctctatcttc ttctgtaaat ctatttttaa ataaagtaga tgctattgct
    48541 attaccaatg gtggtgttat acaagctgca gatacacctg ccataaataa ataatttccc
    48601 tgtcctagaa gcatagttcc agttacatat gctgctttat ttactggacc tcccatatca
    48661 aatgctgaca tacatcctat tactattccc aaaattatag ggcttgaatt ttgtaacccc
    48721 gatagaaagt tcatcatagc attgttaagt gctgaacatg gcccaccaag taacaacatt
    48781 gctacaccca caagacctac gctgacaata ggaattataa aaatcgattt aagaccttct
    48841 aattgtcgtg gtaattttct taacaaatgt acaaatagtt taactaagta acctgctaaa
    48901 aatcctgata tgattccacc taaaaacccc gaacctgtat caaatgatat cattcctcca
    48961 acaagtcctg ccaacatacc agctcttccc gatatagatt gagctataaa tgctgccaat
    49021 acaggaacca tcaagttcat agaatatcca ccaacagatt ttaatgtagc tgctatttga
    49081 ttatattgtt ctgaatttgg gtcaaatgaa taaatccccc ataaaaatga tatagcagta
    49141 agtactccac ctgctactac taaaggtaac atgtgagata caccattcat taagtcttta
    49201 tacaactttt gaccaaacga taaatttcct tcttctgcaa ttttactgct tgataagttt
    49261 ccttttctaa tagctacttt tccatcaata catctttgta taagttcatt agccttatgt
    49321 ataccttctt tgacaggtac ttctattact ggctttccat tgaatctgtc catatcaaca
    49381 tttttatcac aagcaactat tattgcatct gccatttcga tatcttttgc tgttaactta
    49441 ttttctacac ctatagctcc attcgtttca acttttatgt cacagcctaa ttccctggct
    49501 gaatttttta atgcttcttc tgccataaaa gtatgagcta ttccagttgg acaacctgtt
    49561 acccctagaa tcattttctt tcccattttt ataccacctt tctgactctt atatttttta
    49621 tataatcttc cacattctcc aaattaccta taccattact ttcagccaca cttgctcctg
    49681 ttgctgctga cctttttaat gcttcttcaa tatgttctgg attttccaac catatactta
    49741 aaaaagcagc taatgcagaa tcaccagcac atgcagagct gactactgta actggttgag
    49801 cactagcata ataaattgat tttccattat aaaaataaga acctttttct cctaaagtta
    49861 gcaatatatt ttgagcacct tttaaatgca gtaatttaag tacatcctta atatcttctt
    49921 catctcttac aataattcca aatatatctt tgatttcttc atcatttggt tttatcaaat
    49981 atggattata ctgtagtaac tcctttaatt ttggtgaact tatatcgagt attgtcttta
    50041 tacttttatt tttacaaatt ttaaatatat cctcatagta attatcatca ataccaggag
    50101 gtagacttcc acttattgat aagtaactta tatctgctaa tgactgtatc ttatctagca
    50161 tatctagttt ttgtttttca tttacatatg acccagagtt tacaaattta aattcatcac
    50221 ttccatcatt taaaaatata tttatacgag ttgtatcttc tacccaagta ggcaatacgt
    50281 caaatcctct cttttcgctt tcttcaacta tatattttcc tgaaaatcct ccaaaaaatc
    50341 ctaatatctt agattctata ccataatgac ctagtacaaa agttacattt aatccctttc
    50401 cattaggaga atatacagca tttgatgtac gatttactaa ttttctcttt atcccattag
    50461 tagatatatt catatctatt gcaggattcg tagttaatgt atatatcatt gtcttccccc
    50521 ttgctcgtgc tgtgtatgtt ttcattataa taaaaaagtc tatgaaaatc ttttcacaaa
    50581 tagaaaatcg attttcatag acttttcaat ttaattttca gaattattat atctgaccat
    50641 ataatctata attatcctag atataatata caagggcaat ctggaagata cttcatattc
    50701 agaaattgat atatgttcat gtttgtatcc tacaatatat aaatccgaat actttataag
    50761 ttttgcactt tcactacaac agcaagttat aaccttagct ccaactaaat tggcattctg
    50821 tgctgattct acaagctcta tggtatttcc attcaatgaa aatataatta taagttcgtc
    50881 tttttttatt gatttagatt ttattttcat tatgttgggg tcatttataa aaacaacatt
    50941 aaaatcaagt aattgcaatt taagactaaa ctcttttgct acatattcag taagccctct
    51001 tgccaaaata tatatcttac tagatttatt tatagttttt attatattga ttagtgtagt
    51061 taaagatatt tgttctataa ctctctgtgc ttctataaag gatttattta ttatatcccc
    51121 catattttgt atatcatcat tttcatcttt tactgttaat ctatacctaa gttcattgaa
    51181 tccatttaaa ccacattttc taattgctct tgaaacggtt gctggagatg aatatgtttc
    51241 atgagcaatc tctactatag ataattctgg taatattgat tcattttcat ttataaattt
    51301 aattatttca agttccgtct tcgttagatt ttcagaatta cttttgttta gctcaattat
    51361 catatgttat ctccccttat ataagtttta tttgtctaaa tttatcgagt aatataatat
    51421 attacctctt aactacttat ttttatatac aattaagatt tagtcaatgt ctatatatgt
    51481 aaatttataa tataataatt ttttgcttaa agtttattat gttatcttat agcattttaa
    51541 aataaaaaag aattgtacct ctaccaaaat ttggatgaag tacaatagat attcctcata
    51601 ctgatatgtt tatgattaaa agtataaata taaatttcgc tatgaatcat ataattaata
    51661 aatcatttta tttacaatta taacccccct tataaaacta tattaataat atatacagta
    51721 tttataaggg gggttgttta tatttaaaaa ctatttactt ttctcttaat tcttctccat
    51781 tagttcttat tacattttga taccaataaa aactatcttt tttataacgt tctttacttc
    51841 catttccatt gttatctata tccacatata taaatccata tcttttttcc atttcttgag
    51901 atgaacaact tactatatct attggcgacc acatacaata agctaatatt tcggttccat
    51961 cagctatagc ttcacctatt tgttctatat gttttcctaa ataatctatt ctgtaactat
    52021 catgaacttt tccatcttca aatttatcat gcattccaaa tccattttca gctatcatta
    52081 ttggcttttg gtatctatca taatattgag ataaagtatt gtataatcct tttgggtcaa
    52141 ttgcccaccc ccaaggattt gcttttaaat atggattctt tatattgtca gttggattca
    52201 tggtgttttt acttgctgat actgttgtag aataatagta tgataaagct agaaaatcca
    52261 tagtattttc ttttaagatt ttatcatcac cttcctccat aactatattt atgttatttt
    52321 ctttgaaaaa tctcttaata tagactggat actctcccct aaaacttaca tcagtgaaaa
    52381 aatattgtag cctatttctt tttaaagcaa atactacatt ttcagggtca caatcttctg
    52441 gataagatgt acaatctgcc atcatcatac ctatcatcat atctgaattt atttcttttc
    52501 caagcttctt agtcaaagct gtagctatga attgatgatg aatagcttga tatctagtct
    52561 cttctacatt atcaacttgg tctacacaaa atgcaactga attaaatgat tcataatgta
    52621 ttaaatttat ttgatttata actatccaat atttaacttt atttttatat ctatttagta
    52681 ttaattctgc atatctaaca aagaaatcta ccacttttct attagaccat cctttatatt
    52741 ttaatactaa attcaaagga gtctcatagt gaagtagtgt tacaataggt tccataccat
    52801 tatctattac ttcatttata agattatcat aaaactttaa tccctcttca ttaggctcta
    52861 aatcatctcc atttggaaat attctagccc aatttattga aaatctaaaa cactttaacc
    52921 ctagctcttt caaaagcttt aaatcttctt tgtatgtatg ataaaagtct attccactac
    52981 gcttaggata atatccatta ttatctttca tagcaaactt tattctttct atagtcatat
    53041 cagactcata aggtttagat atatctctat ctttatcata catatgtaca tcagctaaac
    53101 accaaccttt gccaccttca ttccatgcac cttctaattg attagctgct acagctcctc
    53161 cccataaaaa acctttagga aacttaccca atttaatcac tccttatttt atttatttaa
    53221 atcatttact attatttacc ttatattcta tagactttac tattcctact aaagacatag
    53281 ttatatttaa ctcgctgaat atggtcataa gagtatcttg agcatgtgca aataacagcg
    53341 aatgtgctct tttctctcca ccagcttccc cttgtataat cttggtttga gctctatgtg
    53401 cttctgtcat aaaccctttt gctttagcta gttttaaatc agcatttcta taatcaaact
    53461 tttccaaatc attaagagca tgtttaattt ctgttctagc ctcacctgca cgaagtatta
    53521 tttgcattgc tacttctact aattcttcat ctattatatg ttcttcaatt gtcatattta
    53581 taatttcctt tcaatttcta aatttaaacc tcttgactct ctaattttat ctcttctttc
    53641 tcataagctt taaaaaatgg ataccatatc ataaatagca atactatatt tattgctaaa
    53701 acaataagac ctctaacatc ttgatttacc ataaaagtag atataccaaa aggaacatac
    53761 cataaattaa acaccttact tggaattgta acaaatccca tactcattga taaataagta
    53821 gttattgata ttactactgt tcctatccac ataggtaaca ttaaaaatgg gttccatgcc
    53881 actggagctc caaatattac tggttcattt atattcatta tagaagggac aatacatgct
    53941 cttcctattg cttttattct tccaactctg gataaacaca tcattataac taatggtaat
    54001 gtagcaccca accctcctaa agttatccag cctgtttgaa taacttcgta aacatatata
    54061 ttagttgcta ctcctcctga tgctactgct gctgcattag ctgcaattgc accaagttga
    54121 attgaataag ttataggaga tagtacccac ccacttattc ctaaagaata tataaatact
    54181 actaagaagt ttaagagtac aaatccaggt aatgtctgtg ctatatctga tactggttta
    54241 aatactctaa ctattatttc aaacatgtca aagttgagtc cataaattaa tccccagcct
    54301 acaaacatta tcactgttat aggtaacata ttatcaaacc acttgcttac aaaatccgga
    54361 agtgctgaat cttctccgaa aaatgaaaaa gaaccaaata aagacattat taatccagag
    54421 aataatcctg caactagcga tacaagcatt ccttctcctc caaacctgtt gaagttaaat
    54481 atagctcctt cattcgtaat ctctggacga atcatcatta acattaatcc agcacctgca
    54541 agaccagcta ctacactcat actttcaaat ttcttattct tcattgtttc cataggcaat
    54601 aaaaatgcta taaataatcc taaaagtcca aatgtatatt gatttattgg acttaaatca
    54661 ggtaaaaagc ttatgtaatt cttcaagaca gaaactatag ttactaatga gcctacaaat
    54721 accattggca aaactttcat tatagttgat tgaactgatt gtacccatat attcttagtc
    54781 atattattta caacaggagt aaatttttca cttaaaaaat ctataaattt attcataaac
    54841 actctcccca taaatatttt atttgtttga tattagttct agtgcttctt ccaaagcctt
    54901 tgcaccatct agtcttccat atgcagtttt agatatacat gctactggaa cgttatattc
    54961 attagccttt tgttgaattt cttccttcat ataatctaaa tgtggtccta gtaataaaca
    55021 atctatttct gataaatact tatctatctc tgactcactt ctcgctttta tatctgcttc
    55081 tatacctttt ttctttgcac tctttctcat actagttgcc ataaaacctg tacttgctcc
    55141 tgaaccacac gccaaaagca ctcttatatt tttcataata atacctccaa tatttttatc
    55201 cattaattta tttcttaatg aactttttat tttattatgt ttatatttta cttcccaaat
    55261 aagttcattt cacataaata tatttcctaa taataggaaa tcatttactc ttaattagac
    55321 ctattaatat agtataatgt atcttataat acgtacattc aattatataa ttatcatatc
    55381 atacagattt tattttaaaa ctatgcgagg gaatctaatg aaaacatcta aaaaagagct
    55441 atttttaaat ttcataaaaa cgcaacatga ttggatagat tcatccacat tagctaatta
    55501 ccttaatgta tcaacacgtt cgattagaaa atatgtaaac gagattaatt ctaatggtgc
    55561 atttatatta tcttctaaaa agggctataa agtaaatctc aatactaatt gtcaaactaa
    55621 gattgatagt tcagagaata tatcacctga taacagatta aatttaattt taaaagaact
    55681 tatagttaat agtaatggaa ttaatatatt tgatttaagt gaagaattat ttgttagccc
    55741 agctactatt gaaggggata tagtcaaagc taataaattt ataggaagtt ataatttaaa
    55801 gataaagcaa tcgaaatttt tattgaaact agttggaaat gagtctgcaa agcgcaagtt
    55861 aatgagctct ataatattta aagaaacggg aagtgatttt ttaagcttat ttgatgtaca
    55921 aaaaatatat caagagtata atttgactaa actaaaagaa aatataatat atatattaaa
    55981 aaaatacaat ttatttataa atgagtatgc tataaacaac atacttcttc atttaatgat
    56041 aactatagac agaataaaaa agaataatta catagactct gttgaagtag taaactacat
    56101 agacaataac gtagatataa atattgcaaa agacatatca aattttttag aatctgaata
    56161 caatataact ttaactagtg cggaattata ctatttagta tttcagttaa caaacaaaac
    56221 tacagtctta aactacaatc aaatggatac taaatcattg tcaaattata tagatgaaca
    56281 ctttgttaaa ttaactaaaa aaataattaa aaatgtatat gacttatatc ttatagattt
    56341 atctgatgag gaatttgttg taaaatttac tcttcatgta aaaaatttaa tcagtagagc
    56401 caaaaataat caagttttaa gaaatcaaat acctcaaaag ttaaaagatt cctacccttt
    56461 gatatatgat atatctgttt atatttgcaa tcagattcaa actttagaaa atgtagatat
    56521 agacgaagat gaaatatctt atatatctct tcatgtaggt tcattctttg atagacaaaa
    56581 attattagaa gataaagttc tatgtgcatt aattactcca aattactatg atttacaatt
    56641 caaaatagta agagaccttg agaagagatt taatgaatcc atagaaatta ttcagatttt
    56701 ttcagatact cataatcttg attttgacaa taaggtagac atggttatta ctactttacc
    56761 aattaacgat agatgcccta taccttttgt ttatgtaaat ccttacctaa atagaaagga
    56821 ttatgataat attcaaagta aatttattca gattaaagat agaaaaaata tacttactgt
    56881 acaaaatcat ttagaaatgt actttagtga atctttgttt atgaaaaata tatatttaga
    56941 tagtgctaaa gattatataa gatttatggg aaatattctg tacgaaaata aatatgtcaa
    57001 acccaattat atagatgatg ttcttataag agaaaaaatg tcttcaactg catttaataa
    57061 caatgtagca attcctcata gcatgaaaat ggatgcttta aaaaccggag tatgtttaat
    57121 tgttaacgat aaaccagtta aatggggtga ggaaaaagtt caaattatag ctatgatacc
    57181 tataaatgaa aaagaaaaag aaaaattcaa ttacatattt gaaagcttta ttgaaatatt
    57241 atctgaatgg aataatgtta aagaacttac taaggcagat aactatagta gttttatgaa
    57301 tagaatagct tatcttattc aaaatatcta aatccattaa tttatttcca atatatgttt
    57361 cttaagttat taacataaaa tagataagct gtcacactaa aaagtctaaa ttaatatgtg
    57421 acagcttttt acctaatata ccttgtttta atactacata ttttttgact gttgtatact
    57481 agttataaga ttgaatattt gtgttgttgt agctgtcata ttctcactag cagttgcttt
    57541 atccattgct tcttctattg tcatagctct atttactata gaaaaataag catctatacc
    57601 ctcttcatta catttaactg catcttctgt tgtggctcca gccaaaccta ttacttttac
    57661 cccatatttt tttgccagtt ttgcaactcc tattggagcc ttgcccatag cagtttgatt
    57721 gtccaatcta ccttcaccag ttatgacaaa atctgcatct tttaactctt cctctaattt
    57781 aatttcttct aatattattt ttattccaga ttctaatttt gaatctaaaa atgctaaaaa
    57841 agcaaaacct aatcctcctg ctgctcctgc tccttctaca ttagctacat ctttacttaa
    57901 gtaattttta actactttgg aaaaatttct aagcccatta tctaactcct caattatttc
    57961 tgatgttgca cctttttgag acccgtatat gtatgcagct ccatttttcc caaacagcgg
    58021 attatttaca tcacaggcta ttttaaactt acattcatct aattccttta atctattttc
    58081 tatttttata tgtcttattt catttaaaac ttttccacct aatcctacta acttgttatt
    58141 tttatcataa aactcaaacc ctaaggcttg aagcatacct atcccagcat cattagtagc
    58201 acttccacct atcccaacta taaaatttct atagccttta tttattgctt cctttattat
    58261 ttccccaaca ccataagttg tagtgtataa aggatttcta agttcagtcg gaaccaatgt
    58321 taatcctgat gcttgagcta tttctattat tgctgtactt gtatttttta ataatccata
    58381 tgttgcatcc acttttttag ctattggtcc agtaacttct atagtctctt ttttaccatt
    58441 catcccttga actaaagcat ctactgtccc ttcaccacca tcagcaagtg gcaatatctt
    58501 tacttgcgca tcttctttaa ccttcaatat cccctttttt attgcatttc ctgcctctat
    58561 tgaagataag cttcctttca aagaatctat agaaattaac attttcatac ttatctactc
    58621 ctttttatta ctccttattt taaacatata attttataag cttaatttat cttttatttt
    58681 atactctaca tctctctttg tatacaactt ataccattaa tattctttta tcttataaaa
    58741 agggagtgtc tcaaaataaa tttcttagtt catgagacac tcttttgtat aaaatcaaat
    58801 atatgtttat tatttcaaca atgataagga ggattatctc tattttaaga taattccttt
    58861 ttagcactat ctaatcattt ttagcactat ttaaccagta tagttttaac ttggttcatt
    58921 aagcactcta catttacaga gttattatct attgatatag attctaattc tttttcattt
    58981 aggttaatcc atttagctgt tttaatattt ttgttaaata ctatgttagc tgattttgtt
    59041 tcttctttag aattataaaa tctaactact aatgcctctt ctttttcagc cttttttaca
    59101 acacttaaca caaggtcctt attagtttcc ttaagtaaac tatatgaata atctacttct
    59161 atttctgatt gattcaattt catagcatta tatggcattt tattataagt ttgtattttt
    59221 gttaaatact ctttagccat atttgcaaca tttgcttcta gtgtagattt ttcatgagta
    59281 actattgcta agtctatttt tatatctcct atcatttgag aatctggagt atgcaacttt
    59341 attcctgatg gacgacctgg gcgtcttgcc atttcttctt tacctaggaa tcctacactt
    59401 ctaaataatg ttatagctat tgtgtcaaat ttttccccta ctatttcaaa ctctcttgta
    59461 ctgtttgtaa gaacagctac tccatgctct ttgtcagaca atccaacgaa tgttagcatt
    59521 ggatatatag aatctggtct ttcactccag tcttcctgtt gccaaacttc catagcatca
    59581 tcatacacac ttctctttat atgtccaaac tgattatcag acacagaaaa ctttgaagct
    59641 atatttgttg gtatataagt tctaacccta caatctcttg cttggttatt tatgttgaat
    59701 actacatcta ttatagcttt atcatttgga acatttataa ctatatcaaa gtcaataaat
    59761 gaatctgctc tattattttt tctagcttgt atatcttttg gtacttttaa tctataattt
    59821 atctttatct cattattaaa tctatttttc tttatagtgg aatttgctac tatattatcg
    59881 ttaaatatta atttctcatt tggaagtggt gaaaaatcat actcatctcc ttcatctcct
    59941 ccattttcca tcaataatac attttcaaaa gttttattta attttttatc aaatatcttt
    60001 aatgtcccgt tttcattaac ttgaatagta taaaagtcat tatctaccat gtcacatact
    60061 tcataagctt tttctaacat atgttcaact tcttttatca tatacgcctt ataccccatt
    60121 gcaggtattt tatctttaaa gtttattgta tataccataa atgaatcata gtttccataa
    60181 tgaacaattt gacggtctat taatcctgca tctattactt ctttatgtac cacttcaaaa
    60241 tccaacttat tattatcttt atcaaatatt tcaaatgctt tcattttagt tataacttgg
    60301 gcgctcacta tttcattcct atcgtaaggc attaagttaa atgctattaa cttatctaaa
    60361 gccatttcac aactcattgc atcaactatt cttcttttgt aaaatgttat taattggtct
    60421 actttttcct cagctaagaa aaatctattc attatttcct ggtgaacttt atctgaacaa
    60481 caacatccaa tgctgtcatg agcatgattt ttcattattt ctttccaaat taactctatt
    60541 aatccatgat gatattcaaa tcctagagaa tatgcaatag aagctagtgg ctccaatatg
    60601 ttagttatct ttgattctat tctagcattt gctgatttta tatccattct tgttgagaat
    60661 atacttctat gaaccctcat atatttccca tctaaaaatt ccccttttat tgtatctata
    60721 tcctcatttt tttctagctc tttaaatatg ttttcatatc tacttaagaa aaattttctg
    60781 tctggataac attcttttaa tttatatata acttcaaata tattcttttg aattggcatt
    60841 tggtcatgtc catttggaag tattatatgg tcagtagttg cacccttatc aagaaccggt
    60901 aaatatttat ccattcttgt tcttagctca tcttcattca ttggtagata ttttcctatt
    60961 gcataaccta atggaagtat ttgaaccaaa acagaagacc catcatcact cttccaatta
    61021 aactctgttt tattagttcc ttttctttca gaacatcctc tccaaaacat tgagtatttt
    61081 atatcaaacc catttagtat ttgtggcatt tgagcacttt gaccaaatga atctggtaaa
    61141 tatcctattt tcatatattc tccaaattca tcacaatctt ttattccata tagtaaattt
    61201 ctaagtatgg attctccacc aactaccatt tcatcagttt gagtatacca aggacctatt
    61261 attagccttc cttcttgaac taattttttt attctctcct tacattcagg cttaactgct
    61321 aaataatctt ctaatatagc agtttgacca tccatcacat aatatggata gttatgatta
    61381 ttttctaaca tatccattat ttcttccata ttatttacaa gtaatattct agattcctca
    61441 gttgagaagt accattctct atcccaatgc atatgaggaa ctatgtgtac attttttttc
    61501 attgcttatc ctccaaaact tatctgataa tattttctgt ctaattaaaa atccaataaa
    61561 aatactactg agtttacaaa attttttaat atttatttta tcactataat taaacctttg
    61621 atttaaatat ctaataacgt atcttttaat gtatctttct ttgatttttt tgtttcctag
    61681 ttattattaa taatattgct gatattatag ctccaagtac tgccgcaaag aaccatattg
    61741 atgctataat aaatcctgac atacttccct ctaaaagcgc caatgagaat atccccgctc
    61801 caggcacttg aagacctata ttgaagaatg ctactataga cccagttatg gctgaaccag
    61861 ctaccaatga tggtataaca cggattgggt cctctatcat aaatggtatt gcaccttcag
    61921 ttattccagc caatcctaat atccaagttt gctttcctat ttccttttct gattctgaaa
    61981 ataaatctct gcctaaaaca gtagctattg taactccaaa agctgaaacc atcttaactg
    62041 atgcaaatat tgcataaggt ataaaatttc cacttgctat tgctcctatt gcaaatgtat
    62101 aggctgcttt atttattggt ccacctaagt caaatgaaac catagctcct attattgcac
    62161 ctagtagtat tgcatttact ccagtcatcc catttaacca atttataaga ccattgttaa
    62221 gtgctgctac aggctttcct actacaaata acatcaataa acctactacc aaagaaccaa
    62281 ctactggata tacccaaaaa cttacgaatc cagctaatgt gcctttggct ggtatattct
    62341 tctttaaaaa ttttactata taaccagcaa gtaaacctcc taacatacct ccaagaaatc
    62401 cactacctat taaatcagct gctagacctg ctgcaaatcc tggtccaaga cctggttttt
    62461 cagctagtga gtaagacata tatgctgata atactggaac catcaatgta cctaacatac
    62521 ctccagaaag ctttcttaat tgccataacc aagaaccttc ttgattgtat agttcttgta
    62581 gaccaaatgc ttgagatgct aatactgcaa atgcaagtat catacctcct gccacaataa
    62641 gtggtattat atgagatact cctgtaagta ttgctgattt tacatctttt ttccatgatg
    62701 atttttcaca atatgatata tcagatgatt tttctatata atcaccttta ccttgttttt
    62761 gtgctacttc taaagcttcg tatattattt cttttgctct ttttagtgga gctgctactg
    62821 acgtttttat gtttggcaaa tgttcaaatc tttctgtatt tttaggtgct acatctgttg
    62881 catatattat tgcatctgcc ctttttatta tatctggcgt atgagggtcc accataccat
    62941 tagctccttg cttttctaca tacacatcca cacctatttc tttaccagct ttaattaatg
    63001 cttctgctga catatatgta tgtgctatac cggcagggca tgctgttatt gctaatataa
    63061 ttttttttga ttcattttga atcctaatct cttcttttat ttgttctttc ttttctttta
    63121 tatctaagtt attaaataac tctttcttag tttttgaatt taacaacata ttcatataat
    63181 cttcatttga cagtctagta actaactcag aaagtatttg tatgtgtgta tttccacctt
    63241 cactttctgg tactgctatt aaaaatatta gctctacttt attatttggg tctacgcttt
    63301 cccaattttc tattggtgtc tctaaggtca tagctgcaaa tgcagcttct ttaactgact
    63361 tagattttcc atgaggaatt gcaagccctc tttcaaaacc tgttggagat aaagtttctc
    63421 tgtacattac agcttctaaa tattcctcat aagatgttaa cttgccttca tcatatagct
    63481 ttcttgctaa gaactttatt gcgtcttcct ttgtttttat tttttgtttt aaaaaactta
    63541 ctaaatttct gattatcttt tcataagttg gtaaatgccg atatatccca tattttcggg
    63601 ctttattggc attttccttt tggaagatac ctcgcataag atggcattta ccagcatgaa
    63661 aatgcaacca aaagtagtaa ataagtagta agatacattt tcgatattaa gaagccagcc
    63721 tttctaattc agcctttgca gactggaaag taccgtgagc ataataccct aatgtcatgg
    63781 ttatgtttgc gtgccccatg atgtattgca gggtgttagg gttcattccc ttatttgcca
    63841 tgttcgtaca gtaagtatgt ctgaatgaat ggggcgtgat gtttggcaac ttgtccttat
    63901 gcgtcttgtt gtacttctta atcagcccac gcaccatact ttcataattt cctgccacct
    63961 ttggcaatcc ctcacggttc aagaacaaga agttgctgta accgtcaaca acaagcggtt
    64021 gtgcttttcc tcggttcttt aaaattcgtt caagtgcctg atatgctctt tctgtcaatg
    64081 gaagctcacg cttcccgttt tttgtcttag gtgtggaaat atagtaaccc acctctgtat
    64141 cacgcaatag ctggtggtct atgttaatca cacggttaag catatcaatg tgtgttgtca
    64201 gtccgcataa ttcagagata cgaagtcccg tttccagcag aagaataact tcatcacgat
    64261 acttgctgta gacattatct gtttccataa aggcaaggag tttttcttcc tgctctggtg
    64321 ttaggataac ctttgcttcc gtatcatctt ccagaacatc actcaacttg aaattgaaag
    64381 gattttttct gatacagtcg tcttgtatcg ccatatagaa tgaagccttt aaggaacgct
    64441 tatagttatc tatcgttttg taggaataac ctttgtcatt cattctgata gcccattctt
    64501 tagcgtcgga ctgcttgacc gtatcaatcg ccctcatacc caatgggtca ttttccagtg
    64561 cgttcataag atactgtcgt cctatttttg tgtttctctt gatgttcttt ctttgattgt
    64621 tcttcttttc gtaaagctgg cagactgtca ttttaccacc cactgtgtcg ataccgtcgt
    64681 caaggtcttt ttttatctgc ttttcttttt ccctcaacga tatatcatca cgttttccag
    64741 caggtgtttt gtctgtcggt acaagtttcc aagcatatac aaactgtggc ttcccgaata
    64801 tatcggtata tttataaacg tatcttccgt cttttctctg gctctctcca agacgcaaat
    64861 tgcgtccttt actgtcttgt cttttcactt ttgacatggt gtaaagctcc tttccgtcat
    64921 ggaatgagcc gtgatacgct actaatatta taccatatct acggctctaa gacatcagat
    64981 ttcgtccagt gtatcaataa ttttttcaaa ctgttttcgt tttatctgaa tacggtttcc
    65041 attgacgata acccagccag agtccagatt ttcctcggca agcctacgca acttcttttc
    65101 cccgatacga aaatatcggg acgcttcttc tatactaagg gtatattttt cccagatagg
    65161 cacatcagta ttgttcatgt tgcaacactc ctttctgtat gtcttatcat aagcagacag
    65221 acggcttcgg aaagctccgt tagtatctca actattccca ttcttgtggg cagaaccgca
    65281 ccatgcggac gtatcattat tctgtgatag caggtcatgg caaagcgacc attccacaag
    65341 ttgctctcgg atcactgcgt gggtcgctca ctttcttgtc ggaaaggtca tggcgtacag
    65401 tccccgtggc tcgctgtatc acaaacgtat ctgtctgctt tattcagttg tcaaagaaca
    65461 atcggcgaaa gccgtaggct tccatgtata aaagcaggag cagggcagga aagaggggga
    65521 tttaaccaat cacgccctgc tggtatctgc ttattcttct tcggtttcta tatctatatc
    65581 aatctcaaag tctaaaatca ttttgattaa ggcttctcga atacgtccct ttaattccat
    65641 atcaacaaca atataaacat tgccgtattc atcatataaa ggacgtaaac aacactttga
    65701 tatgtacggg tcatagaata ccagtaattt ctcaatcgca gtttcatccc cgtccatagc
    65761 tgatgaaatc aaataataag acgggtgctt gtactttttc ttcatttcta tttcttctcc
    65821 tttagtatct ctttcatagt ttctagggca cggtgtctgt gtttgaacac agcccctctg
    65881 gtataattca taatatctgc aatctctgta tcactcattt ccaagaagta atacatcaat
    65941 acattgttac gttttttttc gggtagctgt ttgagagctt ctgcaagttc atcatcaagg
    66001 actttaatat ctatgccaca cacattaaaa attgtgtagt ttgtttcgta gtcgtcccat
    66061 gttgccagac tttctaccgt aatgtctggt aattcgctaa aagatatttc cttgtttttt
    66121 cttcgtttta attctttacg gtagttccag ataatacctt tgacaacttt tttcagctta
    66181 cattcaaact gacactgaat tgttttttgg aagtcagacg gtttcataat ctcacctcct
    66241 ttccagctat gaattgaaaa gtgtttatcc ctctttccgc accatatctg tacagcaagg
    66301 tgtgatttgc ttccaaaaaa atgaaaataa ttaaaaaaac ttttcgggta ttaaaaaagc
    66361 ccgcacaaaa tataaatttt gtacgagcta ctggtatagc gtatttaatt gtaaatagta
    66421 tgctgttaaa ttgggcttga atatactgaa ttgtacataa agcgtttcat acggcaagcc
    66481 ccctttacaa catttaaacc ttaacctttg tctttttggt aatcgtataa atatattcct
    66541 ctggtgttgg gcgcttattt ccaaagtatc gtttaaaatt tgcctgcacg tctgggtctg
    66601 tactttccat agttttgtct atggtatctt gtagcatagc cctaaattca gatacagaaa
    66661 caccttgagc tttagcacca actttcataa tataattcat atttcgtctt ttaagtccta
    66721 tcattagaac caactcccta aaataagtta atcttctttt tcaaaaatta aatctatctt
    66781 tcgcatacag ccttttgcgt caatttctgt gggtacaaac cctgcgtagt gataccccgt
    66841 ttttgcgtaa ctgtcaataa tttctttgtg tttatcagta caaaggaata caactccttt
    66901 cgcattatag ttaatttcta catactcata ttttttcatt tttcaaaact cctttcaaat
    66961 acaaatttat ctttggattt attgactttt acaaactgga attattcttc tattttcaaa
    67021 tcattaccct caaaaataaa attattgatg tcaatcggta aacatattag aacgcaaatt
    67081 atagtgtttg gttctaaaga atttactttt tttgtagaat tatagcaata aaattcagat
    67141 aatctccacc gccagcttct attgccttac ggtcatttat tgcatattca ttattttgct
    67201 ttatccaatc cgaccaaact tccgaattac tttccatttc atatattgaa attaaatctg
    67261 cctttttaca atgactaatt atgttagacc aatatgttat atcatgtata taatcaagtt
    67321 cttctggtgt ccatgataac aataactctt ctggaagttt ctcatggcaa tctttcttca
    67381 tgccaggaac tgtgatataa acaaacccac ctttcttaac aaatggaagc aatttttcat
    67441 ctaaatatat agggtcacgt ccaaaataat tatatgaatc tgtacttact acagcatcaa
    67501 aaaactcttt ctcaaattta agttcattgg cgtcagcttt tacagattta atttgtgcag
    67561 aagataatcc catttttttg aaaaattctt cattttcttt tggctcactc cataagtcaa
    67621 ctgcaaaaac aacaaatcca tattcttttg caagaaatac agaagttaaa ccttgtccac
    67681 ttccaaggtc acagacatag ctgccagacg ggattttatg attttgtaat agttcctctt
    67741 gtaattttat aggattcggt cccataattt ttgtctgtaa gtcgggtgta aaatattttt
    67801 tactgcgaat atattccatt ttctcatctc cattattgta atattttaat agttaatatt
    67861 tgtgacttat aacaatattc attttgagtt cctctgctga aattaaaaag ttatgtttgc
    67921 attcaggaca gaatatgatt attttacttt ttcaattgta atatatttct tgacaaattg
    67981 attaacatgt gtggttaatt gagattttaa atcccaacaa ttttcaactg cgtctgctac
    68041 acttatcaat agaaataatg gcgcataata ttcaatagca agctgttttg tatcacactc
    68101 ttgaagaaca ccttttttaa tcatttcatt aaatatatct tctatataac tgataggacc
    68161 atttacaaga catttttgat aaagcacatt catttttaaa tttctatatt gctctagtat
    68221 taacattttg cgaaaattag acgcaaattc atcagtcacc caaaaatcgt attgtgcaag
    68281 agtaaatgtt attagacttc caatagttgt atttctgtat gcattagggg ttacctctat
    68341 tgtgctttct ggtacttgat aatccttagc tcgcttatta tcaatttgat acatacgttc
    68401 tacgatacag tcaaaaatat cttgcttatt tttataatgt ttatataatg ctccttttgt
    68461 cattcccaag gcttccgcaa tcatactaac agaaacagcc tcataaccat tcactgcaaa
    68521 taagtgtagt gcaattttta atatattttc ttttgtgtca gacatttaca acctccttct
    68581 ttagtaaacg aacgtttact tctgtaaacc attatagtaa acgctcgttt acttgtcaag
    68641 tagtataaaa tgtagtgtgc ctttggttca taggttgatc tctcgatcgc tggtgcttta
    68701 tgccttgcac catatttcct acatacattt ctctatgcaa aagactgttg attgtaaaga
    68761 attgtactca aagctttcct taacgttagc ccccccttaa agcactttct agtatctaaa
    68821 aacatcattc tacaacataa cagatttcaa taaaccttaa tacatcttgt cgtcctcgct
    68881 atcttttgaa cgattgttag aatttctcct ttggttatac ttcttcataa ttacaatttt
    68941 aagtaagcca acgacaatca aaaccacaac aatgataatc caccagtatt gttccataac
    69001 ctacttccct cctttccctt tcaatagcct taaatcatct tccctgtcct atgcagaata
    69061 gagaagttca ttcgtattaa catgtaccat acaatgctta cattgtggaa agttgttttc
    69121 aatcgtttga tggactccct cagcaattct atgagcgtca taaagagcta aattaccatc
    69181 agctaatatt tcaatatcta catacatttt cgctccaaac atgcgggttt ttaattcatc
    69241 aataccatca accccttgct gctgaagcac aacttcccta atctttgttt cagtagcatt
    69301 gtcacaacta tggtctacca ttttgttaat gctttctttg aaaatgtcca aagcagcttt
    69361 taagatacaa ccgcaaatca caacgcttgc aatagggtcg agaatagcat agcctaaacg
    69421 cgctcctaaa atgccaatta aggaaccaac cgacgagagt gcatcagagc ggtggtgcca
    69481 tgcgtcagcc ataagtgcgt cagaatttgt atgctttgca gcatttcttg taaaccagta
    69541 catccactct tttataacaa tggataagac tgccgccgta agtgcgattc cactagggac
    69601 agaaagcgta ttgtactgtc ctgaaaagat tttcttgata cctgaatatc ctattccagc
    69661 acccgttata gccaatgcaa cagagagaat aatggaagcc acacattcca tacgttcatg
    69721 cccataagga tgttctctat caggctgttt ttctgatatt ttaattccaa ccatcacaac
    69781 gattgtgctt aatacatcag aagccgagtg tacagcgtcc gacagcatgg cacttgactt
    69841 tcctatatat ccggcagcga atttaagtaa cgataaactt aggttgataa atagtgtgat
    69901 tttggaaacc tgaatagctc tatttacttt tccgttttgc agaagtctac ccttttccat
    69961 aatatgcctc cttatcctgc cagcttccga aacagacgtt ttgtaaggaa gtagtaccag
    70021 actaaagcta ccaccaatcc tatagagaaa taaagaaccg cctcattctg catggctttc
    70081 gctacccaaa atgatggaag gaagccaacc gcgaactggt agtaactatc aataaaaaag
    70141 ggggctggta ttcccagcaa tgtaagtgca gctagttttg taactgccat accctctaat
    70201 ttattgcttg ataatgtaat aatcataagt gaaacaataa ttgcctgtac tgagccgaga
    70261 agcgccaaac atattgtcat tccaatggac aacttttcta atgaaaaaag taacagtaca
    70321 ataaaagcga tgaccgccga aataattgag ggtactccca accttgtaaa gagatacccc
    70381 gacttaccaa gaggggtaat cgaaaagtac cgtgacactt tatcgtcgat ttcctctaat
    70441 gtaatcattg caaatgcaaa gcagagtaat acaggagcca tgatagaaag tagtaaatca
    70501 aaaatcggat agtatgctcg caaagaaaaa tctgttattc tttcaagaaa gggaatacct
    70561 aatttaatca aagctcccat gacaaaaggc gtaaaacaag ctgcaaacat catagggtcg
    70621 ctcttgattt gtctaaatac ctgtatggta ctggataata tccttttcat agctttacac
    70681 ctcctaaact tttccacata tgcttaactg tatgtcgcgc aactatgtag aggataatca
    70741 acgtagcaat tacaagtacc atatcaaacg atagtaaaac gctttttcca gttataagat
    70801 tcatgcaagc tgtgaatgga aaaaagcgga acagatatgg taacttcaca aacagaccaa
    70861 caataggtgg tgcaaagcaa acaatttcta tcggcataat cacaatgaga aattggttca
    70921 agtttgaaat ttttgtagct gcaataattc caagcatagt aaagattgct gaggtcaaag
    70981 ccgtaccaac tgtgatacca agtaaatgat tgctgccgga aactacccct aatatcaatg
    71041 cgattaccgt agaaatagca atcaacgcaa ctgtttttga aagtatatat tccgatattt
    71101 ttacagggga taccaccata gcatttaata ccttttgact tttttccaaa agaacaatcg
    71161 ctcccatgaa aaacaatccc attgctgccg ggtcagagta gatcataata gaagcaatat
    71221 ccgttttcca atgttccggc aaagcggcaa tcccgcacac atataaaact gttaatataa
    71281 agtagataaa atagaaacca tatttccatt ggaaatgtat atcaccacga attaaacgtc
    71341 ccaatctcat tgaagtgtcc tccctgtaat atcaacaaaa atatcattta atgtaggctc
    71401 actactatga atagaaagca aacggttttc ggaaattaaa ctttttaaca gcttatcttc
    71461 tgtggttcta tcaagcagac attctccggt tttctcgcct ttatcatagt aggtatattg
    71521 tattttggca gctcctcttg acataatcaa attatgcggg ctatccaatg cactgacttt
    71581 tccggcaacg ataaaggcta cttggtcaca tagctctgtt gcgtcaaaca tattgtgagt
    71641 agtaatgata atcgtttttc cgcgtttctt ttccgcaaga ataatatctt tcattaaacg
    71701 actatttgta gggtcaagac cgcttgtagg ttcatcaagg aataatatat cagggtcatg
    71761 gactaacgct ttaatgaaat tcaagcgaga acgcatacct ttggaaaagt cagcaacttt
    71821 tttgtccccg tcattttcca agcctaccat atgcaataat tcatcaatag accgaggttg
    71881 cttttcatat agagaagcaa aataggcgag attttgtcgt gctgtgaatt tctcgtagca
    71941 ggttgaaaat tcaaagtcta ccccaatatt ttcataaaac tgatttgtat gttcccttat
    72001 ttctgtacct gcaactttta cgctgccttt atatcttgta ttaagcccag ttaaaacttt
    72061 ttgaatagtt gattttccag caccagaggg tcctaaaaaa ccaaaaattt ctcctctccc
    72121 aacatggaaa cttacattct ccacaaacgg tttgtcagta tagctaaaat acagtttttt
    72181 tacatcaatc attattcatt cctcctttaa ctttatgacg tttatagata tatagtcata
    72241 taaactgtaa aaaatttgtt tggctacctg cctgtcaaat aaccaaacaa aattgttact
    72301 ctgctactac ttgctgaata ataccattca ctaaaagatt ttgtatcata ttcagttctt
    72361 cgtcctcttt gaattgttcc aaacaggata aaacagaata cagggatttt atgataactg
    72421 tatgcggaac caaaaatata acccctaaat cttccagtat ctccaatata cgaatatcac
    72481 tgtacatatg attttcaaaa atatctgacg atatttttct ttgcagatag tccattaaag
    72541 ataaatcaat ctgcgaaaga ataggcgaag taatcacccc cgttaaactt agcataataa
    72601 cgtcctttgc taaatctcta tggttcttat actttttctt tttaatggtt gtttctatac
    72661 ttgtaaataa ctctttttgt aagcgaaaat tgatttcaac atatagatgt tctttactgg
    72721 gataaaaagc atagaaagaa ccttttgata tgtttacagc agctactaaa tcatcaactg
    72781 ttactttttt taagccgtgt aatgcaaaca gcttttctcc ctctatcaaa agtttactgt
    72841 ttatgatttc tttttcttgt tccgtaaatc gtggcaaact cataacctcc ttatgactaa
    72901 aatatttata tcgtcatgaa aagtataaca tttactgatt atataatcaa tatgctatcc
    72961 aagatattta tgcaaggtag cttccaatgc gtttattgta gtgtccgtgt cctcattaaa
    73021 aatcatgtga cgattaagct ctaaagcaag taattccttt tgcggtacat gaattaaatc
    73081 aaatactttg ttggtataat caaagctaaa aagcgggtcg cctttggcag taattaaaat
    73141 aacaggacat tgtatagccc cattctccag gcacgataag tcagcattaa ataagctggc
    73201 gacaaatctt aaaggataat agggtaaaag catagggtca tttaagcaat cttgttttgc
    73261 ctgttcacta taaaatactc tgtcatagtc taaataagcg tctcctggaa ccttgtagtt
    73321 aggcagcaat tttccaccta cacgaaaccc ccactgtatc agccccataa aacggtgcga
    73381 ccatgcggga tattttgtta agctcatagt ttcttttaat gtagtcagca tgatattatg
    73441 tggaaaaacg gcttttaacc ttgtgtccct acctgccgcc attgcagcta aaatcccgcc
    73501 ttgactggaa cccatgacag ctatgttttc accgaaagtt tctattccgt aagttgttgc
    73561 gtcatataca ttatgcaaca tatcttccat tatataattt tttttgattt tagggctttt
    73621 tccgtgtgaa agatagtgaa cacctattat attaaaccct ctttcgctca atccacatag
    73681 aaaattctca tacatgagag ggtgtgacat agtacctggc aaaaaaacaa tggtaggact
    73741 acttctttct gtataccaaa tagaaagtgt tatcggaaca ttatttgaag aaatgccaac
    73801 ttctttatac atacaccatg cctcctatat gactgattta attttatagt catattatag
    73861 cttattgcaa gcagaaagtc aatagctata aatatatgat ttaaggtaaa attgtcaaga
    73921 aagattccat tgcttaaaat acaatgaaat agcttgtcag tgcagtacat ttgctacaga
    73981 aaaggcagac tatatccgaa aatagagcct gccaacaaaa tgtcttacat aataatcttc
    74041 cagttactat ccttatatag tacaagctca tactgcgaaa ctaaagttgc ctttgtctga
    74101 ttatcaagga atttcacggc tactttgact ttcacattgt ccccgtcctt tgtaaatact
    74161 gggtttacca gttcagaata aaggtagtcc ctgccgatag gttcaagcac atttcccgtt
    74221 acataataag caagctcttt ttctgttgct gtcgggtaca gattaaagaa agtttccaaa
    74281 aatgcggtag cgtcattgac ggtatctgcg tccacgcttg cgtcggcttc ttgtgccttt
    74341 ggctcatagt ctgatttttc aatcgctggt gcaagggtag ggttctgaac gataaccata
    74401 tcgcctcttt atctacatgg attttaacgg tataggttgc tttgacattc gttgtctgtt
    74461 cgccctcttt tatctgctga tctacttcgt aggtagtaaa taaaggctct catactttaa
    74521 atcttgattt ctttgtcatt gtataaatat attcctctgg cgtgggtctt ttgttgccaa
    74581 aatatttttt gaaatttgcc tgtacttctg ggtcggtgct attcatagct tcatcaatgg
    74641 tggcttctat gttttcttga atttccgata gtggaacacc actcaatttt gccccttgtt
    74701 tcagcatttt ttaatatccc gctttttagt cttatcatgg tatcactcca atcctatttt
    74761 ttagctacgg ctaaataact gaatttattt atcttttgat atggtataca ttgaaaactg
    74821 tcatgtttca aacaatatca gacaccctaa agggaaatac ataaataata aagataatct
    74881 ttgccataaa ccctcaaatg ctaaaaacgt attcctaaaa ttaggtttat ctcccataac
    74941 aaaacatgaa aaacacaata ttgctaatat aaaacaccca atgcagaaaa atgaaaattt
    75001 tatgtcattt attttatacg cataaattcc taacagaagc ggtgcaaatg acaaacacat
    75061 aaatccaaca acagagccgt aaccatgtat tttttctgaa agagtattaa gactttttac
    75121 ttctccaaca gagaataagc cagaaagaat acagccgccg attgcataaa tcagcaatac
    75181 tataaaaagg attattgcaa ttagccttga cccctttgaa acaaccgcat ataccttaaa
    75241 attgattact gctaaagtca ttccaaagat taccagccat gtattatata cattatgcaa
    75301 cggtgcttta ctatttccaa gaacactcat aacctgtgtt aaatgactat atcctctata
    75361 tgtgggagct aagataaaag gaataagtaa atctaaaatg aaagctatcg gaagtataag
    75421 cataatgtta tttttcatca tctataccgt tgcttaattt acccagccct ttcaatattt
    75481 tcacagctaa ttctttcata acatctgctt tcacaatagc tattccctgt tcttcgtcgc
    75541 ccagcactaa taatgtatct cctgctttaa tatcaaaaat ttgtcgtgct tcttttggaa
    75601 taacgatttg tcctttttct cctactttaa ccgttccaaa tatgtgttgt ccctttttca
    75661 ttggcataat tacacctcaa ttctaacttt ttatttttgt tatacttttc atacttacaa
    75721 aacaagtata acataaggag tgtagtttgt caaatttaag gaagcgtgta cccctttgca
    75781 gatatacacg ccttattgat taacctatga ttttccagtt cccgtcctta tgaagcgtca
    75841 gctcatattg tgaaatctgc gttgcctttg tctgattgtc gataaacttc acagcaacct
    75901 ttaccttaat gttatcctcg tcagccgtaa atacaggatt gacaagctcg gaatagagat
    75961 agtccccgtt tatcggttca agggcatttc ccaccacata gtaggcaatc tccgtttccg
    76021 tagccgtagg gtacagcttg aagaatgttt ccaaaaacgc cgtagcgtct gccgtggtat
    76081 cagcgtccac gctgttgtcc gcttcctgtg cctttggctc atagtccgat ttttccatag
    76141 cgggagcaag ggtcgggttc tgtacgatta ccatatcgcc gtctttatct acatatactt
    76201 tgacggtata ggttgctttg acatttgttg tctgttctcc ctcttttatc tgctgatcta
    76261 cttcgtaggt agcgataaaa tcgtccgttc ccgactgttc tatatcccaa atcaagacat
    76321 ttgtaacaat ggagctggtc ggtatatctg ttcttatggt atcaaggttc aagtcctgca
    76381 attcctttgt cagatagtta ctgattgcct gcgcccttgc ttcgatagct tccttgctgt
    76441 tgtcccatgt gtaataggac ttacagaagt tcttcacgaa attttcaatc ccgttggtgt
    76501 catttaatct aagctgtatc gtttctgttt catgtacggt gtgcatatca atagcggtaa
    76561 agttcttata aactccaaag ctcacacttg cgataagcac tacccataat gcaatcacag
    76621 atttcttatg tgtgcctacc ttgacagtac gcactttttt tcttttactg gtttttcttt
    76681 ctttttaaac atggtttcca atcctttcta ctgttttatt cttccagcac caatcaagtg
    76741 ctgttgccaa tacgaattat taaggtcggt atatccgata gggtcgcctg catgatacat
    76801 ctgattattt cctacataga taccgacatg ggttacatag cttcctgcat tgtaggtact
    76861 gtggaaaaag accaaatcgc cagcctttgc ctgcgatagt gggatatgct gtgttgcgtc
    76921 atactgcatt tgtgcggttc tcggtaaaga gataccagcc ttgccataac accactgggt
    76981 cagtccgcta caatcaaaag aagtgttcgg gttactgccc ccatacacgt atttccaacc
    77041 ttgatacttc aacgcttcat tcattatctt ttgtgccagt tcgcccgata cttgattgac
    77101 gacaaggtac tggttcacaa gctccacata gaacatattt ccatagccat aacgccagcc
    77161 cccccgtttt ttgccacagc gatagggttc gtataggtta ctttctgacc gctcgattta
    77221 tcccttgcga agttttctgc aaggttaaaa gtatgtttct ttccttttcc tgccacatag
    77281 cccacataac ccccgccata attgtaattt tcatatgcgt acatatcagt acctccttgt
    77341 ataatttata atcaaagtat acatgaaaat tttttgtata gcttgtcgca caatgccatt
    77401 atcttataag aaatcaaaag atataaaaaa ccaattttgt ctatatggta acttttattc
    77461 ctttggtact ttttaatgag ccatatctaa taaattcatc acatatcttt taattctttt
    77521 cgtatcatag acctttggaa ctgtattgtc cattgcttcg tcaatcgttg cttcaatatt
    77581 agccataaca tcaactaatg atatagtcag atttcaaaat cccatataga taatagtcgc
    77641 aataggtatt taccattttc ccctcacgaa tatgtccttc cctttgaaaa cccacttttt
    77701 ctaatgtttt ataagaagca tgatttaaaa tatgcacatc tgtccatatt ttttgtaatt
    77761 ctgtttttga aaaacaaaat tcaattacgc ctttcaacac ttcactcatt agtccattac
    77821 cttgatattg cttagaaagt ctgaaagcca cttttgccat tctatcattt tcaataaggt
    77881 atatccacag ttcgccaatc actttgctat cttgtttatg gacaattccc caatgaaaac
    77941 ttttagtagc tttctctggc ttattaaaaa gtaattctgg atttttttcg ttttttgaag
    78001 gacgtttccc ccaatactcg tataaagaaa tatcactaat ccattctttc aaatcatcta
    78061 tgtcattttt attcattgtt cttaaaataa gatgttctgt ttcaattact ggtttttcaa
    78121 aaatgtaatc ctgcaaactc atggttcatc actccttaaa aattaaattc gttttcccat
    78181 gcaaaagaag cagattcttc taagctgtga ggccaatgac tacaccaatc tggaacttgc
    78241 ggattttcca ctctatccaa actcggcgtg tatggtttaa tatccaagat aggcgttttg
    78301 tcattagcgt caatataagc aatttgtatc agcccactca tataatcaat attgataatt
    78361 tctactgctg ataaagcaat cggatttggg cgtactggcg accttgttgc aaaaatcccc
    78421 attttctctg gagctttttt ataaggttgg tctgtttcca atacgcttct aaaatccgca
    78481 ttgtcaaaat cgctgaacca ccataaaaca ttgatatgac tgaatccgtc taattccttt
    78541 aatgctggaa tatatggtgc ttctagttga atgaaagcac ctttttcatt gttgtagata
    78601 gtacctattg aatttacttt ataagttgtc attatatttt cctccgtttt cttcttgata
    78661 aataaacgat aaaccttaac accatgttaa agtcaaggca gattatcatt ttttacaaga
    78721 gattttctaa aggaatttgg atttctgtta gatagttctc tggatttttc tcgttccacg
    78781 gtccacgatg aactatttga cggcttgaac ctttcatctt atattgactg ttttcttgaa
    78841 gccattttgc aaatgaacga taagcataag aaatattaga aaaatctcca tataccatag
    78901 tacaagccat catagaaact ggttcggtaa aacgaaactt aaaatctcct gtagcttttc
    78961 ctattttatt tacaatggta cataattcta catcaacatc tttttcttta tattcttcat
    79021 tgtgatatat tgagaatgtt tcatcagaaa tatttatttt attttcttta gcaaaagcag
    79081 agagttcttt ccagagttcg ccctcataat aataatttgg tatttctttt cttaaagata
    79141 aaacgcaata actcggtatc tcttttatgg ttatgttaaa atacaattca cttttgccat
    79201 gcaacaattc ttttttagca atctcaattt tctttagttt ttcttgttct ttttgtatat
    79261 tatccataat ttcaatagac tttttatcaa gttgttctat aatggtatca ttactgcaag
    79321 cgagggctaa tgcaatttca gcgacattga aaccactatc acgtaaatat ataattctat
    79381 ttaaagttga gatttgttct gctgaataca tacgatatcc agttaatgaa tcaattttag
    79441 caggttttaa taaacctgtt tcatcataat aacgcaacat acgagtagaa acttgtgtca
    79501 attttgaaaa ctcaccaatt ttgaacattt tatccctcca ttcatgtacc taattataat
    79561 tattgttaat ttatacttca atataaaaag ggcttgcata ccataattat gatacaagcc
    79621 catttccatg ttatcctaca attttccagt tgctatcctt atgtagcaca agctcatact
    79681 gcgaaacctg cgttgccttt gtctgcttat caaggaattt cacagccacc ttgactttca
    79741 cattgtcccc gtctttagtt aagatagggt ttaccaattc agaataaaga tagtccctgc
    79801 cgataggctc aagcacattt ccagctacat agtaagcaag ttctttttct gttgctgtcg
    79861 ggtacagctt aaagaatgtt tccagaaatg cggttgcgtc atttatggta tcagcgtcca
    79921 gtttaccgtc tgcttctggt gtctttggtt catagtctga tttctggatt gctggtgcaa
    79981 gggtagggtt ctgcacgatt accatatccc cgtcagcgtc tacatggact tttacggtat
    80041 aagttgcctt gactgctgtt gtctgttctc cctcttttat ctgctgatct acttcgtagg
    80101 tagcagaaaa aatgtccgtt ccaaactgtt caatattcca cacaatcaca tctgtaacgg
    80161 cagagctggt cggtatatcc gttctgattg tatcaacatt caagtcctgc aattcctttg
    80221 tcagataacc gctgattgcc tgcgtccttg cgtcaatggc ttctttgctg ttattccatg
    80281 aataatagga cttcgcaaag ttcttcacga aattttcaat cccgttggta tcagtaagtc
    80341 ttaattgtat ggtttctgtt tcatgtatgg tgtgcatatc aatagcggta aaatttttat
    80401 atacgccaaa gctcacgctt gcgataagca ccacccacaa cgcaatcacg gttttcttat
    80461 gtgtgcctac cttgacagta cgcacctttt tttctttgat attttctgtc tgtttcttat
    80521 tcttcttaaa catattttct aagtcctttc ttttatttta ctcgtcctgc accaattaag
    80581 tgttgttgcc agtagctact acttaggtct gcatatccta tcgggtcgcc tgcatgatac
    80641 atctgattat ttcccacata tattcccaca tgggtaacat acgaaccagc gttataggtc
    80701 gaatggaaaa ataccaagtc cccagccttt gcctgcgata aggggatatg ctgggtagcg
    80761 tcatactgcg tttgagccgt tctcggtaag gaaataccgg cttttccata gcaccattgc
    80821 acaagtcctg aacagtcaaa ggaagtgttg ggattgctac cgccatacac atatttccag
    80881 ccttgatatt tcaacgcttc attcattacc ttttgtgcca gttctcccga tatctgcggt
    80941 acagttaaat actgattgac taattccaca taaaacatat ttccatagcc ataccgccag
    81001 ccaccatttt tcgcaacggc tatcgggttg gtgtaggtta ctttcttacc gcccgatttt
    81061 tcacgggcga agttctctgc aaggttaaaa gtatgtttct ttccttttcc tgctacatat
    81121 cccacatagc cacctccata gttataggac tgtatcgcta cattcaagtc gtcgatacct
    81181 tgatttttgc aggaagaaag cagggacgca aaatatttac acccctgctt gattgagctt
    81241 tccgtatcta aggaattagg cggtaaacca agactttctg aactctgcat aacatcttct
    81301 gccgtaccgc cactttctac ttgaatgata gccagtaaca cattgacata ctcggagata
    81361 ccgttttctc tggcgtactt ttctaccata ggctgatgtt tcaaaacttc tgcggataag
    81421 ttcatacccg taatgcccga agaaaagttg ctgttatcgt catcggtgtc agcactaatc
    81481 agcaccccaa agaaaaggac aatggaaaag agaataggaa acagactgcc aataatagcg
    81541 atatgtttca atttcatttt ttcttctgtc ctttcttcgt tacaaggtta cggttctttt
    81601 cagtatgttc tgttgtatgt tttgattgtt caaaggtctg tgtctttgtg gtacgctctg
    81661 ttttgtaatt ctggcgtgtt tcctgcgata ccactttttc tatattctgc ctatatactg
    81721 gctgtgccga ctgggtcgtt tttctatcag aagcaccaga agatagagga cgttctttca
    81781 caccattggt tttgactggc tcacttactt tggaagttga agttgtagca ggtcgtttga
    81841 cttcctgtgt tttctcaaca ctcggcttta aagctgtagc tggtcgctca tgggaacggg
    81901 tagctcccgt tgtcgctgat ccgtccatct ttcgtgcctg ccttgcttct tgtgcttttt
    81961 gaagttccat acgcttgtca gcgatattct tcttatgctg ttccagtttt tcagagcgtc
    82021 ccgtctgtct ggactgttgt tcctgcacca cgccacgctt gaagtccgac acgcttgttt
    82081 ttgctttttc ctttgcagaa tggacggcat aagcggtctg tgtcggcata tccttaatat
    82141 tttctttgac agcgtttgcc ttgtccttga ctttattttt cgtatctaag acagcaccca
    82201 cctttgaacc tgcacgctgt cccatactgg aagaagatgt atttccccga ctgtcttttg
    82261 tggaagtttt ccttgtcggc tttccatttg agattgtact acctgccacc gcaccagcca
    82321 caccgccagc ggtaacagca ccagcaagcc gtctttccat acgcctagcc ctatgtgcca
    82381 tatataaata tggtctgcgg aatattcttc gtcccatgct ttgactgtcg ttagcgttca
    82441 aggagaacat actcattaaa tcgcccagtt tcatgtagat accagcgaaa cacactatct
    82501 gtaagaacgc caccataaag aacggatagt ccgtggatat gttataaaac atactggaaa
    82561 tactgaacgc caccgttaca ataagcgtaa ttccagccct tgtcattatg gtattaaata
    82621 ctctcacgat tgcctgcttt gccatgcttt catagctcgg tatcatagag agcaggaaac
    82681 taataggcag gaacatagcg aaaataataa aaagtatctg gctaaataac atcatgcccg
    82741 taagcaagaa tacaaatatc gtgataccca agttgaaaaa caagaggaag aacaccatac
    82801 ctaaacgatt taccacctgc ggtatggtca gattgttgtt ctcgttatcc tcgatttctg
    82861 tttttacgac ttcctctctg gttttcccgt cctcgtcctc tgggcttgcc gatacaagag
    82921 cttctacacg gtctgtcccg atttcttctg cattgctgtt tccaaactgt aagagtagcc
    82981 acggctgttc cacttgaata gagaataggc tgtcccttat caagtccacg ctgtccttgc
    83041 cctcgctgtc ggaattgggg agcatgattt ttgttcccaa gtccaaagaa gcggtgctga
    83101 tgtctgatga aaattcattt atctttttga tgtaatcggg agcataggca ataaatgaag
    83161 ccgacaatac aaacaccaca acaaagttga taacagcgtg aagtgctttg ctggtttctc
    83221 tttttatcag ccccgtgtaa gcaacatata gtcccaccac taagataatg agtagcagga
    83281 agcccacata gaagcccgta gaagaaaaac cgttctgtgt tacgcctgca agtgtctgta
    83341 tgctttttcc gatactgtct gccatatcgt taataaaatc aagtttatag gcttcctgca
    83401 ccacatagcc cgtggcatta gataagtaaa ggcttatcgt ccagacaaaa ttagtgatac
    83461 agtaaagccc gtactgtacc gattttccga taccgtccag ccagttccac ggcaaccacg
    83521 accagctatt atccacataa aaatcaagct ggtagttgga aagaggatat tttgagtaaa
    83581 gattttccgc atttatggta tcgtccacaa gtcccgttgc atgagccatc gtcccaagaa
    83641 gtgaaagcag gataagggaa agtgccacga caaatagagc cattttgaga aagtggaaaa
    83701 tcttcttttt tgtgaacgca ctctgtatcc tttctttcat cactccacct catttctctg
    83761 tatgggcggt ctggtatcaa aggcatgtaa gagttcttca aagactgggt gtatctgcac
    83821 cacaccgaca cgcccgtata agtcctgcaa taaacattgt ccgttctcca aatctcgtaa
    83881 gcgtttctgg ttgttttcgt cgtccttgtc gataccgaaa aattctaagg tctgctttat
    83941 ctcgttgatg tcagtagaac ggaaagcgaa ttttaagccg atattatttt tcaaactttc
    84001 ctttgaaaca tcataggcag actgggtaac aaaataaacg cctgcctgca tagctcgccc
    84061 agcacgtacc agcttgttag ataaggtttc gccttgtgcc acgttcaaga acgcccacgc
    84121 ttcgtccaaa tcaacaatct taaaaatgct tctgtccgaa tggataaaat caagggcaaa
    84181 ggtactaata acaatcaaca ttgccaccga taataattca atggtcgtgt attcgttaaa
    84241 agtagtatct ttatctggca ataccaaatc tgctacttga atgatattga gctggttgtc
    84301 aaggctgata gcattttcca ccgttccgtc cgaaaataat aaatgtgcaa agtcatagtc
    84361 tgtaaaactg tcgatatggt ctgcgatatt tcgtgagatt gcggtatctt cctttctaag
    84421 ttcgtctatc acatgaagca agccccttgt ttcactctgg gtaacagaac gcaccacctt
    84481 acgaagtacg gggaattttt cgccgtccct agaagaaata cccgtaagga atgtcagtat
    84541 atcaatcgca agactttcag cgtcttttac attcttcata atcacgaacg ggtcaagaag
    84601 tcctgcgttg tccttatcgc tggtaaggtt tacgatattg atttcatgtg caatctctgg
    84661 aagtgtttct ttccagttgc cacgctctga tttcgggtct aggataaccg cttgtccccc
    84721 aaagagaaca gagtaataca caagcaggtt gttacagaac gactttccac cgccaagcga
    84781 acccacaaag gcagaagcaa gggcatttgt aaccgttcct tttacgcctt gactggcaag
    84841 ggacggttgc aggtacacat ttcttcccgt atcaacagaa tagcccatat agatacccgt
    84901 agtttcccct aactgctgtg tcgcaccaaa accaagccca gctagaaaat ctgattttac
    84961 atactgcaca tagtcattga tatatcgctt gctggcaggt aaaaattcag aatgaagccc
    85021 cagcatatcc ccagcaggac gcaccagctt tacattgagg tcgtcgtaaa agtccttgac
    85081 ttcatcacaa cggcgtttca gctcgtcaag atcgggtgca gacacccgta taacatagct
    85141 tagcttatac atactttctt tggtctggtc taaatcagtt tccagctcgt ccacgctgtc
    85201 taatgcgtcc actacatttg agcttgtttc acttcctgct tgataggcgt gattgtcaag
    85261 gtctttcaat tcctttttct tgttgcgtac tgtggtaaga gcttttctat tttccacgat
    85321 ttctacattc atgctcgtat caacggggaa tgtgaattgc tgttgctgga aataaaagat
    85381 ttcagaggac ggaaaatcaa gttcccccac aatcgcattg acggtaaagt aggacacata
    85441 gctttccttg tcctcatgtt ccagtcgtaa gtatcgctgg ctttcctcaa tcacacatct
    85501 ggtcggacgg ataaggtcat agtattttat cagcgtttct tttttgtatt tcttctttgg
    85561 tagctgatac tcataatctt cataggcaat accgtccctg ccgtagagat gttccatgag
    85621 atagccaaaa tcatcgattt ctaatcggcg tactttgaaa cgccttgaga ttttattttc
    85681 caacagcttc tccattttca tgtagcggtt gatttcatca ttcggcatgg aaacaaagtc
    85741 attcatcagc gtgtggttca cttcatggag aaactctttg aatgtcagcc aagccgattt
    85801 tttgatgttc ttcagattga gctgttcttc cgttaccatg agcttgaagc caagaaaaaa
    85861 gcggtagtcc acttgattgt ccccaatcat agatactaac gcttcggtct gttcatcaat
    85921 ttttcttacc gccacctcac gaagtttccc cgtaaccaat cgtttggact gttcctgcat
    85981 acttctaatt gagctttctg tagcaatctg caaggcatgg attttaccct cacgggactg
    86041 tgcaattagc tggcgaaagc tgtcatgcac aataaatttc tgttccgcag atagaaagct
    86101 gtaattgtaa ggtatcagct catagtaggc gtacacttca ttgtccttgt tccagacaag
    86161 attgttgtcg atatatttaa tcgggtacat agttcacact ccttactgcc gtaatcgttt
    86221 cgtttaatat ctgcttatcc agttttacgg cttttcctgc ataagtgatt ttgggtcgca
    86281 gggcataggt tatctgtgat ttcaaaaaac tgtacggctt ctttccgtca aacgttttct
    86341 gggacataaa ccaagtaaga gcaacgggaa taccgaagta ttttaaaaat gctccctcaa
    86401 ccatggaaag tggtggcata tccccaaaca gaatgatgaa aaactctgta atcacaaacc
    86461 atgtaatctg tgtaaaggta actggaaaag gtaggttaaa gtcattgatt gcatataaga
    86521 ctttttctac attccagata cccgtgtagc ttttaatctt tttcaagttc tttcaactcc
    86581 tttcaaaatg gaaaaggaca gccatgtttc agactgtccc ttaaaagaga aatacgctgt
    86641 cagtagcaac aatacttgtc gctgatcttc cagcgttaat atggtatctc gcacatacct
    86701 cggcttgttg caatgaagca accgcccata tctaaatctc gcccataggc ttcatagtcg
    86761 atatagttct gcaagctggg tggaatgtct ccaagtgcct gcaattcgtc tatgtagtag
    86821 taggcaacgt ctgtcatggt ttcacagtcg ggataataat aaatattgtc cttgtgttcc
    86881 atgacttctt ccagcgtccc gtaatgaccg ataaattcgt ccaaacactc tacgatgtag
    86941 tcgggaagtt cctctatcat ttcatacatt tcattgagtt cttcaatgga aacgtactcc
    87001 ccaatctcaa tagggaagtt gtcggtatca tggattgcgt attcttcgca ttgttcattc
    87061 aaaccaattt tttctttcac atcttcctcg tcaataggga aagtgaacca agcaccgact
    87121 aaatagccct cattgtactt gccaagatta gcgatataaa ctgccatatc atcaatcata
    87181 agtaccacct catttcctac tctggcagtt caaagacagc gtgttccgtt acaagatagc
    87241 gtctgttttc cagtaagtga gaagcatagg cttcaaagtc aaagtagtat tcttgacagt
    87301 cctcggataa atgtttgaac gtcgggtcgt tcatcagctt ttgtcttgca acatctatca
    87361 tgcttttgca gtcgggataa accgcaatca cgttcctgca aatataaagt gcttctaagt
    87421 tctcatatac ggtaagaagt gctgtatatt cttcctgcat atcgcttgaa agctggcggt
    87481 acataaaatc taattcgttg agctggtaca cgcttgtatg ttcgtggact tcatcagcaa
    87541 agggcagtac cttttcaata atgcggtaat ccccactttc tgcaccgaca cctaactttt
    87601 cttcaaactc ggcaacatct atcggcaggt cgaaccagta tgatgttgtt tcttcgccag
    87661 ttgttccgct cgtttccacc agcacccttg tttcctgcat tgttcctcac gtcctttctg
    87721 ttgtttcatc acatctttta aggtctggca tgacatacca aacacatagt tagaaaaatc
    87781 ttctaactgt ttttcttcat agtcagcaaa gttcagttgc ttcatttcat gccacacttt
    87841 acgtttgtaa gagggcaggt ctgaaatgtt ttcacagcca acctttgcct gcatatcctt
    87901 aaaaatatcg ttcatttcat cactccaatc tgaaattaaa gtaagaaaaa agcagtcgat
    87961 cttaagacta actgctttgt gtgtatggat atgaagttgt caaactgaaa tttaaaaatc
    88021 actttttctt gataagtttc agttttatat ttcttctgtc ggcaatcttc tgaaacatct
    88081 ctaccacata caagcattgt gccttaaatg gtagtaaggt caattcgtca tttgattgta
    88141 tttgtttcat tgcttcttgc aattctgaaa gttctaataa attgactgct acacaaaaga
    88201 aagtctttct acgcccgtca ttatagttag aaagtaagta agaaagaatt tgtgtttttt
    88261 cctgctgttc aagattatat tgctcaatgc ctatgatttt cgctctttct aaatctgctt
    88321 tttgtcgtct gctcgtaata aaaatatcat aatcatcaat gtgttgatat ttttcacacg
    88381 gatattgttt gcactcatag caatattcaa tcattccatg ttcaagacta catcttgcaa
    88441 ttttacatga ttgattacca ttgccacaac cgccacaatg atttcctaaa agcataggac
    88501 acaacccaca attcaatcca caaagagaga ataattggtt tttgcgttca aatcctttca
    88561 tagtattagt ctcctaactt caaatttatc tttgtattta ttgactttta caaactggat
    88621 ttgatgaaag agagtctata ttgaaatcca gtatcgttgg ataattccac tttcactaag
    88681 tcctactgta tcagggattt ctttttccaa cacgccacca tttcttacaa tcgttttttg
    88741 tgatgcttca ttctttttat cacatgttag taaaactttg ctttccccaa actcatgaca
    88801 gataggtaaa atcaatctta acatttcgga cgcataacct ttctgccgtt ccgatggacg
    88861 aacactatat ccgatattac caccaaaatt aaagaggaag tcggataatg ggtgtcgaaa
    88921 atcaatcatg ccaataacat agttatcttt ttttcgtata gccaaaaaca cttctgatgg
    88981 aacatatccg tccttatatt ttgcttttaa tcttgcttca aaatcaatcc attcctcaaa
    89041 tgattgtaca ttttcaagac cagcacaacc gtcaaaacta tctccatttt gtgacatttc
    89101 ttctttatat gacataactt ggtctgcata ttgtttagac ggtctgacta acaatatttt
    89161 acacatctta cttctccccc aaaattccca tttgtcgctt tcttcatatc cacattatag
    89221 cattctcata tcagcaccac aataaaattt tacgcaccga taatcttatt gaacagctct
    89281 aacaatacgt ctttcacacc gccagcattg aataccaaac cgacagcaat caaggcaact
    89341 accaagaagc cgataagttt tgaaaactca cgtttgaacc ctaagtagat accaataacc
    89401 acaatcgcca taagcactaa gctctgggcg ttacttaaaa accatgtgta taaattttgt
    89461 ccgaaattca tttaattgtc ctctctttct ttgatttctt ccatacatct gtcagcttct
    89521 ttgccgacag ttaaaatgca cattaagact acgccgatac ctattccaaa tgataccagc
    89581 aataagtctt tcaataattc ccacattttt tcatcactcc tttacgttgg caaccatttc
    89641 ttcaaccgtg gctgtctgtt gcttgattat ctggtagtgt cgttcggtca gttttgcctg
    89701 cttttcaatc gtttccagat actccgtctg attgtccttg tctatctgtt tcaacatctt
    89761 caaggttggt gcaacctgcc tttgtagcca gttgagtgta cgctccaatg tgtaagattc
    89821 tggttttgtc gtcagcttta cgggtggtcg cccctcgcca atgaaccaag cccagcgtac
    89881 attggttttc cagtcgcttt ttcgcttgtc tggttcttta tcagcgaagc ggatatattg
    89941 attgataata gaaaatgctg ttagttctgc gtcataatgt gtcagcagtt ccacaacagc
    90001 ataataggca cgttcatttt tcaaacgtat ctcaaatcta ttttttatgg ggacttcctc
    90061 aatcggtata ccaagtttgg cgtactgttc gtaattcttt tcataacaac agaagtacac
    90121 ttcacttgaa aatgaaccga tatacagcgt gtgtcccata tcgtatttat ccgtttcatt
    90181 atgctttacc agttccccag aaccatagct tttgaaagaa cggaatttag aaatacattc
    90241 ctcatgttca cacttttgta tcagctctgg tatatccagc aatcccgttc tgtcattgat
    90301 tgccaaatca agacgcttca tcacaccgcc ctcaaccaat gcgtccgtga agaagtcata
    90361 ccagcttcgc tcttgtgcca caaggtagct ttcaaactgg cgacagcctt tgcctttcag
    90421 ttccagcagg acaccttttt cctcgtcctg cgatacatac acaaacacat ctccgatatg
    90481 gtaatgctcg gtgtatttgt aatgtccgta atcttcgtga agcatatagt cgatattgag
    90541 ctttaatata tccttgatga tatgttttat atccattgtg ggaaaacgga tacgcacata
    90601 atcaaacagc aggaacatgg gattgtcggg attgaatttt tccaccgctt ctaaaagcgt
    90661 atgtttcatg tcctcggtca gcgttacctt tcctgcttcg atacggctca aatgttcacg
    90721 gctgatattt gccatgattg caagccttgt ctgcgatacg ccgtatgcac agcgtttttc
    90781 tttcaaggcg gttaaaaaat cagtttcatt cagttgtcat acccccaatc gtgataattt
    90841 tgtgatattg tgataatttc aaggctttat cacaaaaggc gaaatgtacg aaaaaccctt
    90901 attttatgcg ggcttgcaaa ggtttttgtg gaagtttccg ccgtaattgt gcccctctgt
    90961 tagataatga ggggcttgta tctgctggcg tggctaacgc cacaccagca acggctagtc
    91021 cgtgccgtcg cctttcgctt cgcacgtcgc cgtcccgtcc tgccttgcgt atgcaagaga
    91081 gccgatagtc tgtaaaaaat catgtccttt cgggactaaa ggcgtgtaaa attcacttat
    91141 gacacttgtt cccacatcac aatagccacg tcccttgata cgcttctgga aaaactgctt
    91201 tttcacatca gagccgaaca gcataccgta acccaattcg ctgatacgcc ccaagccaac
    91261 acggaagtta aaattatctc tgataccgtc cgagaaatat tttgcgtctg gacgctggca
    91321 ggcaacaata aggaaatatc ctgcttgtcg tcctaacatg acgattttct ttagctggct
    91381 aagtaggctc acactttctt ttgtccccag catttcaaaa aacgccacat attcatcaaa
    91441 gataagaaag cagggcggta aaccaagata ggcatagttt tcgcccgttt tatagtctgg
    91501 gtgtcgcttc atttctttgc ttctttgtac catgccctca taaaaggcat tgacacaatc
    91561 aatcatttct tctttggtgt gatacacatt tcccatgacc gtacctaaat ctgcaaggtc
    91621 agcgttcttc gggtctaata tgtaaagaac agcgttcgta tgtaacagag cttcaataag
    91681 cgtcagcaga aaatacgttt taccgccacc agtcccacca gcaatcagag cgtgagggag
    91741 tgcgtcatat tcccatacaa gatttttcat cagcctaaga cagccgtttt ctgctttcac
    91801 ttcatcaatg gtaatgcggt tcgctatcat gtcataaagc atggtgtatt cgatataacc
    91861 gtcatgtaac gtcttgtcgg tcagctcaca atacaagcca ctttccaatt tatcctctaa
    91921 ccgtaagagc tggtcttgat attttcctaa tgtaatttca cagcggatat gaagcagtcc
    91981 tttttccatt tgataataaa tctttggaaa ccagatgatt ttttcccttg atctgctttg
    92041 caggtcagta aaaaaaccgc tgtcttgtac ggtatcagct tcataccact tgttttccag
    92101 tatcattcgt gccagctttt gacggtgcag gagcttcttg aaactgtcat aacagaagcg
    92161 gtaatacaga aaagcgacca atgcacaaac accagtcgct atcagtaggg ttatgaagtt
    92221 gtaagtggaa agcgtcaaac cgttgtctaa taagctgaaa tgctcccaat cggtacgcat
    92281 gagctgtttc atattcagta gcaggataac cgcaatgaat acaaacagaa gcgtccctat
    92341 ggaaaagtgg tagacaaggt tcttgtcgct ggctctgata cggtgtcctt tgtttaaaat
    92401 cattttcata aatcaatcac tcctttctgg gtacgaaaaa agcagtcaat cctaagacta
    92461 actgctttgt gtgtatggat atgaagttgt caaactggga tttattgttc ttaacttttc
    92521 tgtcgttata aagctgactt acgcacatta acctctgcac agaccagccc agctatatgc
    92581 tccgctgttt catttgtcag tacaaagagc attccgtcat tacggcattt tttatgtgtg
    92641 tcgccattca aggcataaac aaaacctttc acacaggtat cactacaggc attagggtca
    92701 atcagtctct tgcagtcacg agaagtagtc attttctttt gcatatcagc aggaagcgaa
    92761 gcgattatat cctcatactt tccagcgttg tctccgtaaa tccgtgcaaa aacacctgtc
    92821 ttgcgaaaca cccaattcat tactgttttc ttctctagtt ggtatgaagc ggtgtaaccg
    92881 ctttttgctt cctttattac aaggtcacag ccctgctcaa taagtttggt attaagtttc
    92941 tcgacaaaca cttggtgttc tggcgcgatt gccgatagaa attctttgaa tgaacctttt
    93001 tcttttgcca ttatcttttt cctccacaaa tttcaattta tccgtttctt catacacata
    93061 ttataacagt tgcttatatc cgctacaatg aaaatctagt ttgccagctt atttctttgg
    93121 ttgcccctgc ggtgcatggt tctgtggatt gcctacttga ccgcctttat tcttcaagat
    93181 aatatcgtca gccttgatat accagtccac attgacacct cgatagctgg cgtttgctac
    93241 cgtatcggct acgggattga caagctctac ctctgcatta tacggatagt ccttgacggg
    93301 aatatcagca ggaattgata cttgtatcat acgttcctgc acactacatt tcaaatcata
    93361 ggttcttcgt gtgatttctt cacttgttga accgtcgtca ttttctgctc gcacctcatg
    93421 tctgagggca gagaacttca atacaccgaa agttttttcc ttgtctaata caataccgtt
    93481 tgctaatctc ataatcattt ccccccctta cttgctttcc tcggctggca acatatcatc
    93541 agccgttaag atatagtttg tgaaccctcg tcctttgacc gctttaccgt ctgcggtaat
    93601 ctttggattg ataagtttta ctcgctgttc tggtttgaaa tgcttttcgc ctgctttcgc
    93661 tggaatggtt acgataatat catcagccct ttgtacgtca gagtacaagt tgtagcttct
    93721 tgatacgggc gtaaagcgtc cgttaatgcg ttgctgttca atcttgtttt cgccagcaaa
    93781 ttccaagttt ccaaaagtct gcgccatgtt cggcactaca tattttaatt ccatagtgtt
    93841 ttacctcgtt tctttcttct tttttaagtt tgttgattgt gctttcttat tctggcaatt
    93901 agggaaatac cagcaatccc ccagatagta aagggtaaat caatgcttcg cacccttgac
    93961 tatccgtgtg cttgcaggtt gttggcagat aagccagaat aagtaaacgt ctgccgtttg
    94021 acagcttcgg cggagagcgt gatttttctt ttctcatacc gttaccgcct tatgatttct
    94081 tcattttacg gcgtttgtaa agatatgttc cagccagtcc accagcagat gtaagcaaca
    94141 ttaccagaaa tgccatgaca tttgtgttgt cgcccgtttt aggactgtct gttggtctgc
    94201 tcggtttttc tggtgttgtt ggcgtttcgg gtttctctgg gacttctggt ttttccttaa
    94261 aagtaatcgt ctgtccctcg tcctcaatgt ccttatgctc agtaactttt ttcggctcgt
    94321 ttggattgct taaatcatac aattcttcaa aagttacaag ctgtttgtcg tcaagagaag
    94381 tagcgtcaaa ggtaaaggta acttccactt tcatagtttc gctgtcagcg ataaacgtat
    94441 aatcactttc cacacgtttt ccattgataa gaagctctgc attttcttct ttcaacatct
    94501 gccagcccac aagtttatac tttgtaccaa cttccaagcc ctctaaggtt acagtatcaa
    94561 tgattgttac gtcttttcct gcttcaagct ctttgttacc gtccttatcg gtagcagttg
    94621 tatgtatttt gatgatacgt tctgtaataa gtaccgtctg cccgtcgtcc tcaatatctt
    94681 tatgctccgc aactttcacg ggttcgtctg gattgcttaa gtcgtataat tcctcgaatg
    94741 ttaccagatt tttaccacca agctcggacg cattgaatgt ataagaaatt tccactttca
    94801 tttcttcatc atcagcaaca aaggtataat cgctttctac acgtttcccg tcaatgataa
    94861 tctcggcgtt ttcttccttt aacatctgcc agccttttaa ctgatactta gtgccttttg
    94921 taagtccgtc taatttgaca gtatcaacga ttgttacctc ttttcctgca aggattgtct
    94981 tttcgccgtc tttgctggtt gctgtggtat ggatagtgat ttctttttcg tattcatcag
    95041 tcaaagttcc taaatcaatc acaagattat ttcttgatac cacgatttca aatggtggaa
    95101 taagctcaaa acctttgttg ctgtcagagc gtaattcttc aataatataa gtatcgtaag
    95161 gcaatgcacc tttgctgtcg tctggttcag aagttccaaa ccacacaccg tcctcgctgg
    95221 tctttcctgc gttggtattg tgcttatgtg aagcccagtc agaagaagtg gagaattgcc
    95281 cgttatcatc agttaccaca acatgacttt cgcccgttgt cttgcttgtg atcctaaagg
    95341 gaacatcagc aagacgcttg tgtgtgcctg caccgatttt cacgccctca atatctccac
    95401 gtttaatctg attgtagaca gagtgggctt cgtctgttaa gtccacgatt tttccgtttt
    95461 ctgtgattgc aaaatcaatc ggcttcgcac cgtctgtcaa gtaaccgttt ggagcttgtt
    95521 tctcaacgat acggaaattt ccgtaaggca aaaggtcagc ggaagtagaa gcgataccct
    95581 caatgtccgt atggattgtt tttacgactt catttttctt gtatagcttg ccctcaacca
    95641 aaacagaatt atcatttaag gaaatgatgt caaaggcagt atctttcaag gttgcacttc
    95701 cttgtggttt ggtatcgccc gtttctaaat ctcgtttctg aattttgaca ccgccacgaa
    95761 tgactttgtc tgatacagaa aactggttac ttccagttaa tacggcaagg tcgccgtcct
    95821 cagtaatctg tgtaaggtat aagcctttta tctgttcttc actaccgttt gcctgcatat
    95881 atgcaccgtc taataagtag cccgttggtg attttgtttc ttcgcaagtt agtgtaccaa
    95941 gaggtaaaac cgcttttccg tcctgcatat agaaactgtc gccagatact ttgtatgcgt
    96001 ctgctaattt tgtgatgtag tgggttgtcc cgtcgctgtc tgtttcagcg attgtctttg
    96061 taacccatgt acgagtagct tcggcaggaa gattgtcttt agtgtagaag cctgcataat
    96121 atttccatgt aaactctgca ccctctaaag aagcgttacc ttgtgggttg gctttctgtg
    96181 tttccatgtc aatcttgaaa agctcaatca aagtatcggt aacttttggc gtatcagata
    96241 ctttcaaagt cgctgtcttt ccagcttcaa cttttaagga atatatggtt ttatccactt
    96301 taaatcccat tggtgcagtc aattctttga tatatacggt agtagctttg acttctgcaa
    96361 cctctgtatt tccgctgttg tcggtcgtaa gggtagcaag ctgttttgtg cagtccttat
    96421 cagaaaagac accgtaagtc gcaccagcga tagagtaatt cccgttaccg tctgtaatgc
    96481 tggtattatt ggaagttttt tgaagtttgg catttccaac atttaacttc gcccagaatt
    96541 gccctaattc ctgcccctcg ccagaataga tataaccgcc acatttatag cgtcctttgt
    96601 tttctttgac aaaggctttt gcaccagcaa acacttcatc ttgcgtagcc tttggaattt
    96661 catcataaga agctcgcacg ttatcacatt gccagcctaa gtgaacactc aatctttgcc
    96721 agacaacaag ctgtcttaaa aggtaggcat gattgttgct tatctcattg tggctggcgg
    96781 tgtattgctt cacatattcg atagataaag caacatcact tatctggtcg gcactcatac
    96841 gggagcttgc gtcagctctg gtcttatagc cgttcttaaa atctgtgtta atgtcaatac
    96901 agtaagcgtc ctcgccttca acggtcaaat gcccctcgtt aaaggtagaa ccaatcgaac
    96961 cgtcattcat taccttttca acgataccaa cacgttcttc actttccgtc cagtattgct
    97021 tactttctgc atgaacaagt gtagtcggta aagcagtaac gacagtcgca aaggcaagta
    97081 cgcccgtaca caatcgtttc aatatctttt tcataattct aaatgctcct ttcattttgg
    97141 gtaataaaat agccgttcaa taagaacggc tggaaataga aaaggaacgt cattttaggc
    97201 gttccatagt ctatgaaata ttcaattttt ttcttgcttc aatactgatg tgccgtacca
    97261 tatctttgca tatctaggaa aactagcgta tcaaggctca ttcattggta gtaaattagt
    97321 agtaaattga tgtgtttgtt ttcttgaaaa tgctgataga tactgtgttt tagcggataa
    97381 tcaacttttt agtatgtttt ttttgaggaa aaaaacaagg ttttcatttg tgattttctt
    97441 aaattccaaa attacgccct ccttaaatca tttaatgcta tgaatatagc ataaaataaa
    97501 ttatgaaaat gtttttttga aattatacac acaatttctt cttaaaaaat aaagatttgt
    97561 gtatttatac acaaatctct atcttaacca atattgctct attattgctc tcataatcat
    97621 cataattgga accttatctg atatattgta cccatttact tgtttaattg ttgaatagca
    97681 atataaactt atatctgcaa tttgttgcaa ttgattttca catatatgtg ttaaagctac
    97741 taccttacaa cccttattaa ctgctgtctt tgctgcttct ataacttctt tcgtttctcc
    97801 acttaaacta agtgcaaaaa acatatcttg ttcacctaat tttcctatat catgaagtac
    97861 ttcatgtctt tgactatagt aagttatatt atcatgccca cctctaattt cttttactaa
    97921 tatctcacat aaaggaatgt tttgacctat tccataaact ataatactcc tagatttttg
    97981 aattatatct gctactttat ttattttttc ataatctatt agctctaatg tcttttttat
    98041 atctgattca aaaccatttt ttggctcttt atcctcattt tttaactctt cttttaaatt
    98101 attttttagt tgagagaaac catcatactc cattttttta catagcctaa ctatggtatt
    98161 tgggacagta aaaaatttat ctgctaaaga ttgtattgat aattttacta tttcttcttt
    98221 gttttttctc atatattcaa ttatcatgtc ttctgtatct gtaaatttat actcatattt
    98281 ttttgctctt tcataaaatt ccatagtttc tcctccatct attttattat tcataagtaa
    98341 aattcaaaaa tattagctaa aattttcgtt aatataatta taatttaata tttttaattt
    98401 attaatgcat actactcttt ttattataca taaaaaatgt gtacttccta tattgataga
    98461 gatgattcaa gtttttattt tgatacatct ctatcaatat ttttttagaa aatacacatt
    98521 tttttcaaat acttattttt aattaaaact ttaggtaatc tattctttat atataattat
    98581 tagacttgaa aatatcttta aaatcaacca attcaatatt atttcttttt aaccacattt
    98641 taacttcctt atcacatagc attgcatgtt catatactct ctcttgaata agagaagatg
    98701 attttataag actataatct ataaatcctg gatgagtaac catcaatgtt atatctttat
    98761 ctaaatttat atatttttct tcaaataatt taacaaaaga tttatttaac ttgtaaaaat
    98821 cattctgagg atatttactt ggcatgctaa tacatgaatc caaataatag ggacaacttg
    98881 gtataccgta ttcttttgca gcatcacaca ttgctgatat tgatacatct tcttctatac
    98941 catgtatatc aatatactca ggcaatttac tcatatacaa cttgtaagtt tcaatttgag
    99001 cacaaacttc ttcatatact tcttcataat taaaaacctc tttacctgtc agtagttgcg
    99061 ttcttcttat tttgctagaa acaaattttc caccttcatc taacaaattc tttatcttaa
    99121 tatgttcttt gcaacaaggt tctcctatta ctaaattaac atgtaaacca aaacatacat
    99181 catcattttt taccatttct atagcttgtc ttgaaaaagg catattcacc atgattccag
    99241 cacttgtaac aataccgttc ttataagaag atattatccc tagtgtaaca ccttctgaat
    99301 atcctatatc atctgcccta actactaatt tcttcatttt atgcatctgc ctgctttctc
    99361 aactcatcaa gttgcatttc catctcatcc tttactttaa caacatccgt tcctatgatg
    99421 atttgaactg atgtattact caatttaatt acccctttgg ctcctgtttt tttaatatta
    99481 tcatcattca aaatagtggc atccttcact tctaaacgta atctcgtcat acaattatta
    99541 agagtcacta tattttcata accaccacaa tttttaatta tctgtttagc catatatgaa
    99601 aaattaccat gagaaagttt taaattcttt tctttttcac taactttatc acctatctct
    99661 atctcaactt cacgtcctgg tgtttgcaca ttatctttta ttattatata tttaaatgtt
    99721 acataatata atacaaagaa tacaactcct acaggtataa ctaaccacgc tttatctcca
    99781 taactaaaac ttaagacata gtcaattata cttgctccat taaatgaacc caagcgagca
    99841 cccaataaat atagtacaac tccacctaga ccagaataaa aagaatgaat tatatataac
    99901 tttggagatg caaataaaaa cgaaaattct attggttcag ttactgttgc cataaaagaa
    99961 gtcaatgctc cagcggtcat tgcacctttt acttcttgct tctttttatc ttgtgctgtt
   100021 ttatatatag cataagaaat agcaggtatt gaaaacatca taattatgta aaatcctgtc
   100081 cagaagaatc ctgcatttgg gtctcctgcc ataaatctag gaatttctcc tcttataact
   100141 tctcctgttg atgttgtata ttcacccatt tcaaataata tgtaagcatt taaaacttga
   100201 tgtaacccag ttggtattag tgcacggtta cagaataaaa acaagaatat tcctattgca
   100261 ccagctcctc ccaaccaaaa accaaattga ttcattgcag cttgtggata tatccataat
   100321 aaactaaata tatatgataa aattaaagca accactggtg atagtgtaat tacacatttt
   100381 tctcctgcaa agaagcttaa aaatgctgga actttaactt tatatgtttt attgtaagtc
   100441 catgctatac aagctccaac aattatccca ccaaatacac ctgcatttaa tgtatcattc
   100501 aataactcta aatttgactt aaatatcata tatgcaacta cggctgcaac cattacactt
   100561 gtcttgtctt tagactttga gtaggcacta gctgctccta ataaaaataa gtagtccaca
   100621 tttgaaaata ctatattaga tatattagat atagctggca cattgagcat atttggacca
   100681 aataataatc ctaatatacc tgctgctggc attacagcta ttggcaccag catagtcttt
   100741 cctaaaagtg acagttgttg catcattttg tttaagaatc tcttcatatc caatcccctt
   100801 tctatttcgg tttaattttt tgtgaaaacg atttattcac attttatatt ttaaatatta
   100861 tatttgttta aacaaattgt caatattttt tattcatttt atttttatca tttagtttaa
   100921 catataaatc cttttaagtg tattgctata tctagtctat ttttttaatt catttttttt
   100981 attttaaaaa tatgtttaac catgtatttg aaacaaccca caaaataatt ctattttgtc
   101041 ctttttatgg ttgatatgat tctattttca ctatacatgt ctaaacacat ttgatataat
   101101 ttgttcatat cagttcaata atattactaa agacctttaa ggagggatag aggtatatgg
   101161 ctaaaaataa attttcagag atatatgaag tattgaaaga ggaaatactt gatggtaaat
   101221 atacaagtaa tatgatgctg cctactgaac ttcaacttat tgaaaggttt tcatgtagca
   101281 gaaacactgt acgtagagca atttctcaat taaacacaga aggatatgtt caaagtataa
   101341 aaggcaaggg tgttgtagtg ttagaaaata gttgttctaa tgattttttt ctaaatatgc
   101401 acaatttcaa aggtgtagaa tcgattgtag aagataaaaa ggttaatact gctactagtg
   101461 ttctccactt cagcaaaatc ttaattgata ataagttatc taaaaagaca ggttttaaag
   101521 ttggtagtga agtatattac cttcacagac taagatatat tgataacata cctaaaattc
   101581 tcgacattaa ctattttcta tgtagtatag ttaaagacct tgatgtttct atagcacaag
   101641 gctctattta taaatatata gaagagtgtc taggtacaaa aattgtttca tccagaaaga
   101701 tatttaaaat tgaaaaagct acagagcttg agttaaaaac gctacctcta aatgattata
   101761 attgtgttgg tgttattaaa aatagtgtat atactgatga tggaaagctt tttgaatata
   101821 ctgaatcaaa gcatacacct gaaacatttg tattcatgga tgttactcaa agatattaaa
   101881 aaaattatgt ttaattaaac ataatttttt tacgtttaga cactttatcc catactaacc
   101941 tcactattct atatacaatt atatgtttat acaaataatt atttattgta tattttagct
   102001 ttaatattag tttaacgctt gacaatttgt ttaaacatat tataattaac ttataaatta
   102061 caggaggtat caagtatgaa aaattggtgg aaaaaagcaa ctgtctatca aatatatcca
   102121 aaaagtttca aagatagcaa caatgatggt ataggtgata taaatggtat tatagaaaaa
   102181 ttagattatc tgtattcttt aggtgttgat ttattatggt tgactcctat gtacgtttct
   102241 cctcaaagag ataatggata tgatatagaa gattattata atatagaccc aaaatatggg
   102301 acaatgagtg actttgaaaa actcttaaaa gaagctcata aaagagacat aaaaataatg
   102361 atggatatgg tcctaaacca tacatctact gaacataaat ggtttaaaga atctaaaaaa
   102421 agcaaagaca atccatatcg tgattattat ttctggaaag atgctaaacc tgatggttct
   102481 gttcctaata actggatatc cagatttagt ggaactgctt ggaaatatga tgaaaccact
   102541 aaccaatatt atttacattt atttgaagaa actcaagctg atttaaattg ggaaaatgaa
   102601 aaggttcgtg aagaatgtta caaaatacta gaattttggg ctgataaagg tattgatggt
   102661 tttcgtttag atgtagtcaa cctactctcc aaaacacctg gattacctga tgaccctata
   102721 acaggaccaa aaggagatgg aagaactcac tacgctgatg gtcctcgtat acacgaatat
   102781 ttacataata tgaatcaaaa agttttcaaa cctaaaaata tagttactgt aggtgaaatg
   102841 tcatctacta cacctgaaga gtgtatcaac tatactagag aaaatcgaga agaactatct
   102901 atggttttta gcttccatca tatgaaaaca gattataaag gaggcgcaaa atggactaat
   102961 gaaatgttct ctctggataa attaaaaaaa gcacaatctg actttcaata taaaatgtat
   103021 gaaggaaagg gatggaatgc tctattttac tctaatcacg accaacctag agctttatct
   103081 cgatttggag atgatagatt ttttcgtcaa gaaagtgcta agatgttagc cataacatta
   103141 tttggtctac agggtactac atacatatat caaggtgaag aaataggtat gacaaatgcc
   103201 tactttacta aaatagatga atatgatgat gctgaaagta agaatgcata ctatcatatg
   103261 attaaatctg gtattgatga aaaggaggca ttgcttatac ttcaacaaaa atccagagat
   103321 aatgcccgta ctcctatgca atgggataat actatttata aggggttttc taatcataaa
   103381 ccgtggttaa aagttaataa tgacaatatt agtgtagaaa atgagcttaa tgattctcgt
   103441 tcagtatttt atacttatca aagattaatc aaatatcgta aacaatatga tatttttaca
   103501 gaaggtactt atagattgtt agatgaaaat cataaaaatc tatttgttta tgaaagagag
   103561 tataaaaacc aaaatcttct tgttataagt aattttactc atgataatgt agtatataaa
   103621 ttacctgaaa cttatttgaa taaattaaac tacacaatac ttgaaaccaa ttacactaga
   103681 gatataattg aaaataaaat ggaaataaaa ccttacgaaa gtataatgat atattataaa
   103741 taaagttatt tatgtaaaaa tcggtataac accctggtgt tataccaatt ttactaaatt
   103801 caaagtaata tttatagaat atctatagat tacaataatt atttgacttc tacatcatta
   103861 tatttctttg aatatacttt agtcatatag aaatatatag gaactacaat tatcatccca
   103921 cctaatcccc aaactatctt cataggttca tcaatacctg cttttatcag taataatata
   103981 cttataataa ctgcaaatat tggtataatt gctcctccag gtattctaaa atttacatct
   104041 ttaccagcat acttctttct caatattagt acagctaaac atgtaggaat atattgaata
   104101 aatctagata caacacttat ttgagataat gttgtgaatg aacccgacca tgctattagt
   104161 aaagttccta tgacagatac tataattgct atataaggag ctccattttt attagttttt
   104221 cttatagact taggcattaa tccttgttca accaaagcag cagcagacct tggtgtaaat
   104281 atggatgatg caatatttat acctccaaca gatactatag ttcctattgt aattatatac
   104341 ccacctatag gacctaacat cttaatggca gcatctgcaa caggagtagc tgaccctgct
   104401 aagccattac ccaacacccc tatacttatt cccagtataa gcatatatat tactgatact
   104461 acaaacatta ccattaccaa tgctttaggt acatttttct tagggttctc catatctttt
   104521 gctgcaacag ctaaagattc aaatcctgta aaagcataaa ataaagttat agatactgct
   104581 acaaaagctg atgacgcact ttgacctttt tgtattatta caaatggggt aaaattagaa
   104641 ccctttataa agaataatcc tacagctata aataaaacta ttggtaataa ttttcctata
   104701 gtcatgatat tatttaagtg cttagattgt ttcattccca taaaatttat aatcccaagt
   104761 cctacaacta atataccaat tattatattt ttagtaagtg gttctgctgc ttgtggccat
   104821 acagatgata gtgttacagc aaagaaattt gccatagtag cccaagcaat catactaact
   104881 atccacttca taaatccaac ttcaaatcca acaaaatctc caaatgcctc ttttgcataa
   104941 agatagggcc ctccatcagt atcaaaccaa ctacctgctt cagcaaaaca taaagcaata
   105001 gaaacagcta aaagcataca aaaaactaat actaatatac ttgctggacc tatatctgta
   105061 taagcatcac caggtaaccc gaatatacct gaccctatta ttgcattgat tcctaatagt
   105121 acaatactcc aaaaacctaa cttaatgcct ttttccattg ttattccccc caaagccaac
   105181 ttaatatatt tatatttttt atttagatgc ttctttaact attgccataa atattttttt
   105241 catattatca taatctctag tcatcatttc tggatgccat tgtatcccta ttacaaactc
   105301 acttccttcc ttttctatag cttcaattaa accgtcttta gatgtagctg aaacaatata
   105361 tcccggtgct actttgttga caactaagtg atgaaaacta ttaactaaaa cttctttttc
   105421 tcctaatatt tcatataatt ttgtcccctc ctttatctgt actgtatgtg taggtacatt
   105481 agatagatgt tgctgattgt gtttaatata agcaccttca attaaagata aatcttgata
   105541 caaactacct ccttcagtta catttataat ttgttctcct ctacatatac ctaaaactgg
   105601 ttttttcata tctaaagcat gttttaataa tttcatatca aaactatctc tctttggtga
   105661 tattgccccc aacttattat gaggttcttc tttccatatg agtggattta catcttgtcc
   105721 cccagatagt ataagcgcat ctatattaga tacctgctcc tttataatct catcatcata
   105781 tacaatcggt acaatatatg gtatagcttt acacataact actgattgta tataatcatt
   105841 atttacataa gccctttcat agccaggaaa cattcctcct tcatcaatta gtaaattacc
   105901 tgatattcct attattggat atttcttttt agccaatttc ttcacccctt aacttatttg
   105961 tgaacaataa aaaatgctac ttctcttaaa gagcaagtag cataccaaga ttttatttat
   106021 ttgaacatta taatttattt tagaaatact ttttttgaat acgagtaata taaataactt
   106081 tatttactta tattttattt taatcctgtt tagtttgact tttttaaatt gttttaagta
   106141 caactaatag gtaaaatagg catttagatt ttccttttta tcaacctatt aaatactgtt
   106201 taatatattt tttccccttc tatttaattc acttcccttt ctaccagatt cacatattat
   106261 caaatccagc tcttttaaca tattaagtat tccccttacc tcaccttctg ttatattgta
   106321 gcctaattca tttattgaat taacaatacc atttctacct atatttttat taagattatt
   106381 ggcatttttt aaacactcca ttactaactt tactttctct atagatgttc tatcctttaa
   106441 tatacttatt tctttactaa aatcttcagt tatatttaat aagttatgag gtaaatcatt
   106501 tattaaaata acatcctcag aactcataat gttaatatac atagcagtat tttttaattc
   106561 tcttatatta cctggccatt catatgcatt aataatgtct tgaacatctt gactaattgc
   106621 tctcttcctt ttcataaaat gctttaacat aacttctata tcttcttttc gctctcttaa
   106681 aggtggtata tttatgggca atacatttat cctatagtat aaatctgctc taaatctatc
   106741 tccttttatc atttctaata aatttttatt tgtagccgca attactctaa catctatatc
   106801 tattacattt tctcctccaa ccctcattac ttgattctct tgtaatactc taagtaattt
   106861 gctttgtaag tatataggca tgtctcctat ttcatccaaa aatatagttc cattgttagc
   106921 ctgttcaaat aatccttttt tacctccttt taaagctcct gtaaaagcac cttcttcata
   106981 tccaaaaagt tcactttcaa gtaaattttc tggcatagct gcacagttta ttgctataaa
   107041 tggctgacta tgtcttggtg atgcattatg aatagactga gccatgagtt cttttcccgt
   107101 tccactttct cccgttataa gaattgtata atcagattca gctattttca tacctaattt
   107161 cttagttctt tccatcttcg ttgaaactgt ttttatatca tcaaaagtat atctagcaac
   107221 ttgtcccttt tctctaagct tctttgatag gttttgctcc aattttctta tgtaagttat
   107281 ttcttgaata caaaaataat atccagtaac tcttccaaaa ctctctatat tatacttatt
   107341 tacgtttaag tacttattat taaattttat aacttcatca tgtgccttac tcaaactaaa
   107401 aatcttttta atattctcat tctctaattc atctatattt ttccctataa tattactttg
   107461 aatatctagt atatccctta aactattatt gcaaataatt atgtttctct tatctgatac
   107521 cattgccata cctaagtttg ataaatttat tatagaattt agttcatctg cttttatagt
   107581 aagttctttg tatttagtat ttattcctga atataaacta attatttcat ctgtatactt
   107641 aattagcctc tcagtaattt ctttatcatc cagtttgagt tttgctatta tttgaataaa
   107701 cgttgaacta tcaatatacc tatggcctaa atcaataact tcttctatat attttggaac
   107761 taaacttgac tctcctggcg ttatagctat cttaatattt ctatattctt cattgggatt
   107821 gtatggtata aaattcagat gatttattcc tatattgtat aaattagata ttgtttccaa
   107881 tacagtatgc ttattatcgt ttactactaa tacatctatt ccttctggca atgaaaataa
   107941 cttatatata tccttttgct ttatgctcct atttatagtt attatctttg agacatcttc
   108001 tacatatttt tttattttta atactctatc atctatcatt accaatatta tgtcatcttt
   108061 tattaattcc ttctctgtta ttttatttaa ataataattt tttatcatta ctttatcttt
   108121 aaatatcatt tctagatttt tatttaagaa acattctaat ttagacaacc catcagttac
   108181 tactgctatt gttttcattt gattactcct tttaaaatat actctactct tttataatat
   108241 acatctgatt ttcactttaa tagcacaaaa aattgtacat ttagtatact aacatattcc
   108301 tttattagtt ttatgtccct aaatatcata gttgcaatat ctatcatatt tcctaaactt
   108361 ctatagagca aaaattgtgc caaattaata attttcttaa ttttattcta aagttcctca
   108421 atagtattta cagacttagc acttatagct tataagtctt tatattatta atctattttt
   108481 ataggttaat tgtacaaatc atatatcact tttacccatt aaatgcatta taaaaaagat
   108541 ggaataacga ttcgtcactc cacctttttt ataataaaaa attgtatatg taaacactat
   108601 ttactactct tctaagtaca aacagtatct acatactata acctttcacc attagattct
   108661 attacttgtt tataccagtc aaaactcttt ttcttaatcc tagacaagtc tccacttcca
   108721 tcatcatact tatccacgta tataaaccca tatctcttgg ccatctcacc agtagatgca
   108781 cttactaaat ctatacatcc ccacggagta tatccaaata aatcaacacc atcttctaca
   108841 gcttccttca tttgctctat atgtgctttt aaatactcta tacgatagtc atcatttatc
   108901 actccattag attctttttt atcataagct cctaaaccat tttcaactac catcataggt
   108961 attctatatc tatcataaat ttcatttagt gcatatctaa gcccttcagg gtctatttgc
   109021 catccccatt cactagactt aagatatgga tttttcactc cacctaatat gttgccactt
   109081 gtattatctt ctttagaatc actacttaca catgtagaca tataataact aaatgcataa
   109141 aaatctacac aaccttcttt taaaatttct aaatctcctt tttccatttt tatttcaata
   109201 ttattttctc caaaatatct attcatataa gttggatatt cgccacgcac ttgtacatct
   109261 ccacagaaat aattcattac tctactatct ctttgagttt taactgcatc atctggatta
   109321 caagtataag gatacattgt tgcaaatatt tgcatacatc caacttgata atttgaatct
   109381 atttcatgag ctaacttaac agccttagca cttgctacaa attgatgatg taacccttga
   109441 aaacgaagtt gaggtatatc tacttggttt ataaaatctg tagtcccttc atttaatatt
   109501 ccttgtgata agtagcctcc cataggcatt gtagctgaat ttatttcatt aaatgtcagc
   109561 caatatttta cttttccttt atatctttta aatattgttt cacagtaatt catatacaag
   109621 tctattacat ctcttgaaac ccatccattg tatttctctg ttattgcaaa tggtatttca
   109681 tagtgagata ttgttattaa tggttctata ttatatttta aacattcatc tatcacattt
   109741 ttataaaatt taagtcctgc ttcatttggt tctttctcca ttccagttgg aaatattcta
   109801 gtccatgcta ttgaaaatct aaatacctta aatcccattt ctgcaaataa agctatatct
   109861 tctttgtatc tgtgataaaa atctattgct tcatgacttg gataaaatgt tcctttttct
   109921 ataactctcg ttattctttt acttactttt tgagaacctc cagtacacat atctgaacaa
   109981 gaaggacctt tcccatctaa attccatgct ccttcacatt gatttgctgc tgttgctcca
   110041 ccccataaaa aatctttttt aaatgacata cctatatcct cctattataa ttcttcacca
   110101 tttgattcta ttactttttt ataccaggca aaactcttct ttttactgcg ttttaaagtt
   110161 ccatttccat cattatcttt atccacatat ataaatccat agcgcttctt catttctcca
   110221 gtacttgcac ttactaagtc aatacatccc catggtgtgt acccccataa atcaacacca
   110281 tctaactcaa cagcatctat catggctttt atatgagcac gtaaataatc aattctataa
   110341 tcatcattta tatttccatt ttcatctgga ttatctactg ctcctagtcc attttcaact
   110401 ataaataatg gtttttgata acggtcatat aaagagttca tagttattct aagccctaat
   110461 gggtctattt gccatcccca ctcacttgca tctagatatg gatttttaag acttgcaaaa
   110521 acatttcctt ctgttaaaat atttactttt gggtctgcac ttgtaagtct tgatgagtaa
   110581 tatgagaacg aaataaaatc tactgtgttc tctttaagta tctttttatc atcttcttcc
   110641 atcactatat ttattccttt tctctccaat tcttttaatg catatgttgg atattctcca
   110701 cgagattgta catctataaa aaagtaattt tccctatctt tttctataga tttccatata
   110761 tctagtgggt tacaagtatt aggataagta tttccagctg ctaacataca ccctatttta
   110821 aattcttgat ttatgttatg tgctagttta gtaactaacg cactcgcaac taattgatga
   110881 tgtgcagctt ggtattttat ttgttcttca ttttctccct cttcaatata gagacctgca
   110941 cctataaatg gtaaatgaag tatcatgttt atttcattaa atgttagcca atactttacc
   111001 ttacctttaa accttgtaaa aataacttca cagtatttta catataagtc tactagctta
   111061 cgatttctcc atgctccata tttttttacc aaatacatgg gaacatcaaa atgacagatt
   111121 gttactactg gttctattcc atactttaaa cactcatcaa ataaatcttc atagaatttt
   111181 agtccctctt catttggaac atcctcaact cctgttggaa atatcctagt ccatgctatt
   111241 gacatacgat agcatttaaa tcccatctca gcaaataatt ttatatcttc tttataattg
   111301 tgatacatat ctattgcttc atgagctggg taatagtgtt catcatcaca ttcaaacatt
   111361 ttcattttcc cagccaaaac tggaaatcta tcttttcctt gcggtgtaac gtcaacatta
   111421 gctagacctc taccatcttc tttatatcca ccttcacatt gatttgctgc tgttgctcca
   111481 ccccataaaa aatcttttct aagtgccata attctacctc caataattta tttatagtaa
   111541 ctttatttta aaataaaaat acatatatat aattcttaat taatagaact ctcttttacg
   111601 ctaaaacagt tatcaatttc tgactattat ttacatgctt ttgtgtattt tctacaatat
   111661 ccacataatc agaataatta gtaacaacta ctggtgtttc taagcaatat ccttcttttg
   111721 aaatactttc tatgtcaaaa gttattaatg tctgaccttt tttaatctta tccccttgat
   111781 taacaaaaga tttgaaatat ttaccttcca actgaatagt atttaaccct atatgtatca
   111841 atagttcaca accattatca gatataattc ctattgcatg ttttgttgga aataaagtca
   111901 ttacagtccc atcaaatggt gccactactt ttccttcttt aggtgttatt gctacacctt
   111961 ttcccaatat acctgttgaa aacgctgcat cttgtatctg ctccaaagcc tttacttcac
   112021 cttttattgg gctatatact acttctcttt tgtttttttc tataacgcct tgcccattat
   112081 catctttaga aatttctact atagcatcat ctttccaaaa aaataatgtt aaaacaaatc
   112141 ctactacaat agctactatt attgctatta tagttgcata aacacctttc atatctccag
   112201 ttgttggatt tatataatta ggtataccaa atattccaag tccacccatt acataacttt
   112261 ttacattcat tatccccatt acagctcctg ccacaccacc acctacacag ctatatatga
   112321 atggtgtttt tcttggtaaa gttattccat atattgcagg ctctgttaca ccacatatcc
   112381 ctgaaataac tgcaggtata cacagctctt ttatcttctt atcttttaat ttaaagtaca
   112441 ttgctgctac tactgctgtt tgtgcaaaag atggtacaaa tgctcccact aatattgtgt
   112501 caaaccccat agtcataagg tttgacatag ctattggtac taatccccaa tgtagaccaa
   112561 atattacaag cacttgccac aataaaccag ttaatgcacc acataaaatt ggtgaaaagt
   112621 taaataaagc taaaaatcca tttccaacta tattagaagc ataggtagct ataggcccta
   112681 taaccataaa tcccaatggt aaagaaacta ataaaactgc cattggtaca aagaaattct
   112741 ttactacatc tggtattatt ttagcaaaca ctttctccaa cttagctgct aataatacta
   112801 ttaaaattac tggtactact gttgaagtgt agttcattgc tattactggt aatcctaaga
   112861 aagttatata tactggtgat tcaaatattg ttccagtaaa tagattgtat aaaggttgac
   112921 ctgtagatgc tagagtatct aattgaatac ctgaatagca taaaactgca cctataagca
   112981 ttccaataaa tggttttaat ttgaatttct tagcagctgt atatccaaga attattggca
   113041 tatactggaa cattgcatct ccaattgcat ttaacataat atatgcacca tcagtttctc
   113101 catacaaacc caatgctgta aatactgcat taaatccttt tatcatacca gcagcacaca
   113161 gaactcctaa tattggttga aaaactcctg atattatgtc tataaactta ttaagtaatc
   113221 cttttggcgc atctgagtct gaattatcta ttgtatctcc tcctaatcca gccaaatcgc
   113281 acacaacttc ataaacatct ggaacatgat taccaataac tacttggtat tgacctgcac
   113341 ttttcattac agtaactata ccatccattt tttttagcac atcatcattt gctattgact
   113401 catcttttaa tttaaaacgt agcctcgtta tacagtgaga taaactgcta atattatcct
   113461 ttcctcctac attcgcaatg atttcttttg atagttgttc atactttctc attttttctc
   113521 ctccattttc tttttgaaat atgaaggttt ggccaactta atgtcaccac ccaatatata
   113581 taaacctaat tattaggatt tatatctgac ttaatacttt tacttaccac tctttcaacg
   113641 tgaatagtta agtataattt ttcctcatct gttaaatcgt agttgtattt tttatgtata
   113701 aattcatcca acttttctat gaatttataa gcatttttat atttaacttt tattacattt
   113761 aataaatcat cttcattatt ttcatgtaaa ttattactaa caattcgttc tgcaaaatac
   113821 tttaagtgag taataaatct atgataataa actgaatctt catcaaatac tattctgtaa
   113881 tggtatttaa ccatatttga aatttcttgt attatttgtg taatctcata tatagttttt
   113941 atactttgat ccatttgtgc attaactata tgcagtgcta taaatccagc ttcatcttct
   114001 gatagtctaa tttcaaattt tttttctata taatccaatg cctctaaccc tattttaaat
   114061 tcactcttat aaaatctttt tatatcccaa agtaatacat tttttacact tactccttca
   114121 cgagctcttt ctattgcagt atacatatgg tctgttaaag aaatataaat actatcattt
   114181 aatcttttcc ctagtttttc tttagcatat aaaattattt catctgataa ttccatatat
   114241 cttataggaa tatctgctat tagttcttta aatttatcag atatatttgg gtctgaaagt
   114301 ttgaatatct tatcaatttt atcctttgat atatgctctc ctgtacgttt tttataagct
   114361 aaacctctcc ccataactac tatttcctta tgattttcat cagttgtaat aattacatta
   114421 ttattgagta ttttttcaat aatcattgtg atgccccctt tattagcatt aagttaaaat
   114481 aaatcttttt taattattta gaatatttaa aatgtaattt attacataaa aaaaaaccta
   114541 tttattacac attaaataga ctcccatgag tcctgagtaa taaataggtt tagcttgtat
   114601 ttaaacaatc actatccgtt tgtattttat tttaattatt atttattata tgttagcaaa
   114661 tttatttttt agtgtcaact ttttctcaat attttaattt taaataaatt atataaattg
   114721 aatcttcaaa gtactatttt tatcaataaa caaaataaaa aaggtattac tttctttaag
   114781 taatacccat ttatttttaa tttaagtggt ttttcttaat ctcatcaagt agtccatctt
   114841 ctaaataaat ttctaatgca catcctacca ttgcctttac tgctttgtga agtttatcat
   114901 aagcttcctc agaatttgca taatttagaa attctttttc atgaacatat accattggac
   114961 ttatatctaa ggctatttct gtatacatag tagggcaaac ttgacttaca ttacctatat
   115021 ctgtagaacc tactggacca tctttacctt ctaatatatc tgttatacct gcctcaatca
   115081 aattattctt tgttatcttt tgaagtactt tgttatttat tatgttgtca aaagaatttt
   115141 caaagtatct ataagaaagc ttagctcctg tcattaactc tgcacctttt gcacagttta
   115201 taactttttt agttacttca tctaaataac ttctttcagc agctcttacg aaaaacttac
   115261 aagctgcttt ttctggaact atatttggag cctctcctcc atttgaaact ataccatgta
   115321 ttctaacatc tgattttaca tgttgtctta gtgcatttat cccagcaaaa gtaagttgta
   115381 ctgcatctag tgcattgact cccatatgag ggtgactagc tgcatgtgct gatacccctt
   115441 caaaactaaa ctctaatgaa tctatcgcca aagccttaca gtttatatta ttaaaagctt
   115501 ctatatgcat ttgataactt acatcaacat catcaaaagc tcctgcctta actaaatcac
   115561 attttcctcc tgttgtttct tcagctggtg ttcctattag tacaattttt cctttaaaat
   115621 tttcttttaa cttacttaat actatacaag ctcctagtgt agatgctgca atccagttat
   115681 gtccacaagc atgagctggt tctttatttt ctccatatcc aggaagtgca tcatactcag
   115741 ctaaaaatgc tatggtaggt ccatcattat ctcctaattc agctctaaaa gcagtctcca
   115801 tattacaata tggataaact gtatcaaatc catattcctt cattttttct actaagtatt
   115861 ttgatgatat gtattcttct tcccctaatt caggattgtt aaatataaaa ttacaaactt
   115921 cttcaatttc ttttccaagt tcattctcta tctcataagc tctcttcttt atactctcta
   115981 tcataattta cctcctacta gaatcctaga tataatccta ttgtcaaaaa tgccattaca
   116041 agaattgtta atactaccat taaaggaatt acgaatctaa cccactttga ccaaggaata
   116101 ttggctactg ctagtgctcc cattaaaaca cctgatgtag gtgttatcaa gttagttaca
   116161 cctataccaa attgataagc tgtaactatc atttgtcttg atacatctac taagtcgcca
   116221 agtggtgcaa gtacaggtat tgtaagtgat gcaagccctg atgctgatgg tattaaaaat
   116281 gctattaatc cttctattaa gaaagttaaa tttataaata tagtttttgg taatccattt
   116341 aataaatttg ctgcagaatt taaaattgta tctattataa atccattttc tgctattatt
   116401 acgattccac gtgcaaatgc tatacacaat cctgctgtaa ttaaatctcc tgctccactt
   116461 ataaatgaat taactatctc atcttgttta agccctgatg ctattcctga tattatacct
   116521 atagctgtaa atatcattgc aatttcagtt atgtaccatt ctagtcttaa aactccatat
   116581 atcataatcg ccatacctat tgtgaaaatg gctattacca tggcttctct ttttgtaaat
   116641 tcctttatat ttgtatcact attaaccatt aattcttgat ttagtgatat atcatgtact
   116701 aaagattttt tagggtcttt tttaacttta ttggcataca tcataacaaa tcctatagat
   116761 atagccatat atattataaa cataacaact ctaaactcta ttccagaacc tggtactatt
   116821 tgtgataatg cttgtgctat tcctacagag aaaggattcg tagtagctgc tccaaatcca
   116881 gctgttgctc ctataaatac tgtggccact gctgtcaatg aatcatatcc catactggtc
   116941 ataagtggaa taaatatcat ataaaaaggt agtgtctctt cactcattcc aaacgtcgtc
   117001 ccacctagtc caaatagaat cattgaaatc ggtattatta aaaattgaaa cttcttcatt
   117061 ttatttacag tatgagctat aacagcttct atagctcctg ttttattaac tatcccaaaa
   117121 gctcctccaa ctattaaaac aaatccaact acttcagctg catctataaa cccgtttata
   117181 ggtgctgtaa atacatcagt aattccttgt ggatttgatg gtgctttttc ataagttcca
   117241 gctacaacaa ctgaccttcc gtctatatct actctttcaa aatttccact tggcactatc
   117301 caagtaagaa ttgccattaa cactattagc aaaaatatta ttgtaagtgt ctgtggcata
   117361 gtaaactttt tcttttttaa actgctcatt tttaatctcc ccacttttta aattaaatat
   117421 tttattattg catcccttta tcctattttg tatagatgta aaaaagctca acatggatac
   117481 atgttgagct aaatgtgcta aatacaacat acctgcatct tccctttatc ttgtttaaga
   117541 tagctctcca tcaaaattcg ggataatttt gatgacagta ctgtacctat taaatacagt
   117601 cccagcacta gcttcggaca ctagcacttc ggcacttact ccttttatat tgcctcattg
   117661 gtttccaacc tcttcaatat taatcttagt aaatgcaacc tctacctcaa tctgtttgtt
   117721 agatgaggta attcttatta atttttatta attcaaagta attgtagcat aatatgtcga
   117781 gattgtaaat attttcagta taataattct tactttatga tttcattcca tttttcacaa
   117841 ataatttttt ctccatataa tttaaatact gtagtatatt ttaaatacac acaaactttc
   117901 cacaaatttt aaattattat aataccttta taataaaaaa taaaagctat gtaaacttat
   117961 caatttacac agctttatat acattaatct actccaagta cagctttaag ctttgatgct
   118021 attgtaataa ctcgtggacc aaatataact tgaactgagt ttttcttttt aacaactcca
   118081 cttgcaccca attcatttac ccagaagcca tcttcataga atccatcaat tgaatttagc
   118141 tctaccctaa gtctagttgc acagtttgta acatttttta tattattact tcctcctaaa
   118201 ccttctatta tagaatgtac aagctttgta tctttatcat ctacttcctc ttctactgca
   118261 ttgttgtatg ctgttttacc agcatctaca gattgtcttt ctctatattc tttcttacta
   118321 taaagcttaa cttcttctga acttcttcct ggtgttttta tatcaaactt cttgattgcc
   118381 catgtaaata ttatataagt aactataaaa aatattggta tcaaaaataa taatggtaac
   118441 gcatccactt tttgtggttg taataaatta ggaaacatat ttctaaatga ttctcccatt
   118501 atagaaacat taaacatttc tgtaaataca tacgtcaatc ctgccagtgg tacatatgct
   118561 acaaaataca ataatggtgc aacaaatagg aatgtatact ctattggttc cgttacccct
   118621 accaacatgg ctgttactat tgctggtatc aatatactta ttgctttttt cttattagca
   118681 ttatcagcca acttatacat agctaaagct gctgctggta atattgcaaa atgtattaat
   118741 aaacgacctg ttgtgaagtt acgagttata taagatagtg tatctgggtc tcccatttga
   118801 gctaatctta tattattaac accctcgtaa attgctccac ctacttccat tgttccacct
   118861 actcttgtat attctatagg gaatgcaatt aagtgatgta taccaaatgg taataatgct
   118921 ttatccattg ctccaaaagt aaatgttcct aataatccac tagaacctat ccaattacca
   118981 agtttagata atgccaaccc tactggtggc catataaagt acattgctgt acccaatact
   119041 attgatgcta taaacatcat aatcattgaa aatcttggac ctgagaaaaa agataatgca
   119101 ctaggaagtt ctatgtcaac aaatttgtta tgtactgcac tagctacaaa tccagctatt
   119161 atagctccaa atatactaca atcatatgaa aagattccta agaaagaacc atataaagaa
   119221 cttcgactat atgcttctgc ctctcctaat ccagatgcca taaacgcttc tgctgtaact
   119281 gtatctgaat ttataccatt tgctgctaac aatgtactta taactgtgtg cattcctata
   119341 aataaaacaa ttcctcctaa tgcaccccat cctttttcct ttttagataa tccaaaggct
   119401 atacctgtaa caaagaatat tggtaagtat ctcattacca taaatcctaa atcgtttatt
   119461 actttaaaga atacatttat aaatgaccct tcttttatta gtccgctaag ccctaatgca
   119521 gaaacgtttt ccatatttgc aaaagctgac cctaatccta taaatactcc tgctacaaca
   119581 agtaatataa caggtatcat cattgctcca gaaagtactt gtaatttatc cttcatagta
   119641 ttatttcctc catttttatt gaaatgccag gctatataat gcatatatat atacttctat
   119701 tgctttgtat aatgtatcta tacttatatt ttcatttgcc tgatgtgaat ttggattatc
   119761 cccctctatt gtgggtccaa atgcaactcc attttttaac actcttgcat aagatgcagc
   119821 tccttttgta aaaagttcgg cttcttttcc aaaaccttgt ttatatgcat ttgataattt
   119881 atttattaat tcactatctg gttttacata cagtaatttt aaatccttat atatatcaac
   119941 tattaaattt tctttttttc caatttcatt aattctatta gttataaact cccaacttat
   120001 acccttagga tatctaaagt ctattttcat attcaattca tttttctcta agaagatact
   120061 cattatacat attgtagaaa ctcccatatc tacatcttct ttatacatcc ctaatttttt
   120121 tccatgatta tcatctgtaa agtatgaatt taaaatatcc cttattataa cgcctttatc
   120181 atttagtttt ttaattttct ctaaatcttt tgctaaacta aatgcacagt tatatgacct
   120241 gtgtggattt ctcgataaag ccctttctcc tgtatatctt actaatactt taccttcatc
   120301 taattcttct atctctgtat aataagctaa tgattctact aaatctttct tatcattagt
   120361 tttaaaaaca gcctcaattt tgtcacatac aaatccatct tctttgtttg actttatatc
   120421 aactaaattg tgatttctaa atttatcttt atctattttc tttcttagat tgaagtataa
   120481 aatacctttt tctccattta ctattgggaa gtttccatct ggagaaaatg caaattttgg
   120541 ctgttcattg acactaaagt aatgctccat acattcccaa gtcgtctctt cagctccacc
   120601 cactatcaat ctaatctttc tcttcggctt ttcattaagt tctcttaaga aaagtaatgc
   120661 atataaaatc cctatcaaag gtcctttgtt gtcattaact cctctaccat aaagatagtt
   120721 atctttttga catactttaa aaggtttact cttccaaagt tctttattat atattggcac
   120781 cacatctata tgattaagca cccctactac ttcttctcct tctccatatt ctatatgaat
   120841 tgcatatcca tcaaagtctt ttacaacaaa atctttgtct tttgctattt gaataagctt
   120901 atcgaaggca tttcttattt ctatcccaaa tggttgattt atatctgttg tactttcatc
   120961 tctaattgaa ggtatttcaa ctaaacttct aatatcattt atgatatttt cttgattgga
   121021 ttttaaataa tcaataatta gttctttgtt tactatcatc ttaattattt atcacccctt
   121081 tatattaatt ttacaaagca tttcagttca tatctacatt ataaattttg aatattattt
   121141 tttcaatatt tcaaatactt ctctaagtta ccataatgat acggtaaaca atcaacagat
   121201 tatgacaaaa tcatactata cctattacta atattttaac ttatctatta cgtctttttt
   121261 aatgtaagtt tattccaaaa atacataaaa aaagatgtag ccttagctac atcttcttat
   121321 atctattcaa cttccattat tatgctatta atatctacat ttccaggttc tatcctatct
   121381 tttactgttc tcttaacaga atcagcatca tccattataa ctacaggagt tattatattt
   121441 aaatcatttg acgttataaa atctaaatct acttccatta ttaaatcttt agcttttacc
   121501 ttatctcctg cctttacctt aacatcaaac ggctttcctt ctagtgacat tgtctctaaa
   121561 cctacatgta ttaatatatt tgtattatca ttactcttaa tcattattgc atgctttgta
   121621 tcaaatacat tgactatttc accatcaaca ggagaatata acttaccttc acttggtatt
   121681 attgctactc catctcccat catcttttgg gcaaaaactg catctggaac atcttctaag
   121741 ttcactaaat ttcccttaaa agggctatat attttctcaa tcttattttc ttttttctta
   121801 aatatattaa acataacaca ctctccacat tataaaattt tatgataata tttttcttaa
   121861 agcttttgct acaccatcat ttacattagt atcagttaca aaatctgcca tagattttac
   121921 ttcatctgta gcatttccca tagcaatacc aagacctgca aatttaatca tggatatatc
   121981 attttcatta tcacctatac aaataacttc tttgctatct atacctaata tatcacaaaa
   122041 ttttttaact gcaatacctt ttgaagtacc tttactcata acttcaaagt ttatctttcc
   122101 agaacttact acttctaaat cttcttgttt tttaaattct tcctttgctt ctctcaaaga
   122161 atctacgttt tctgagaaaa gtatacattt taaaatttca ttatcagctt tttctaataa
   122221 agtttcacaa cttgcatttt ctattatttc aattctgtct tcttctttat ttttactatt
   122281 tattaatcta tatggatgtt cttcacctat ttcattgttg gatataacta ttttacagcc
   122341 tttaaaatgt ttgtttaaat tatacttttc acctattgta tagattttct ttagagcttc
   122401 tttgctcaaa accttcttat actcatatcc cagtaattta aaatatgtcc cattagttga
   122461 tataatatat atatcatccc ctaaaacact tgtaaaatat ttcatagcat tataaggtct
   122521 tcccgtaact aaggctacct tgataccctt ttccatggct tcttttagtg ctttaatatt
   122581 ttcttctgat acttcaaatc ctttacccat caaagtacca tccatatcag tacaaattaa
   122641 tttatatcgc atttgtatca catcctagta agatttttct aatatttcaa caaggtcttc
   122701 tttctttcca aaaggtaaaa atcctaaaac tggacagctt gttatttgtt ctaattgttc
   122761 ctttgttaca ttaaactcag acatttttgt cttaagcccc actctcttta aaaaactttc
   122821 tatttcattt cctaaagttt tagctgcttc atcatcttcc actttttcta attcttggtt
   122881 tagtattctc gctactttgg caaatttctc tatattatcc ttatagaact tttctgcaaa
   122941 ttttgggaac actatagcca aagcctcacc atgaggaata tgtgtaactc ctcctattat
   123001 ttcacttagt ggatgtggtg ctgctgctcc agcatttgcc agtgaacttc ctcctaatgt
   123061 atctgctact gctaactttg ttctgtattc tatattattt ttatcttcca ttactttagg
   123121 tagatagtta atgactaatt ccatagattt ttcagacatt atctctgtaa aatcattagc
   123181 atttggattt atataacttt caaatgcatg agtaaaagca tcaaatgctg ttgatgcagt
   123241 aattctctct ggcagagtta acataagctc tgggtcaact atacattctt ttgagaaaca
   123301 attttgatga aatattgtat ttttctcgct tcctctcgat attactgctg cttgtgtaac
   123361 ttggcttcct gttccagaag tagttgatac agctattaat ggtaattctt tttcacttac
   123421 cttatcgtat attttaaatg gatttgtata tgtactaaac atataatccc aatctatttt
   123481 ttctaaacca aaagtcaatg ctaatacttt tgcagtatct atacttgaac ctcctccaac
   123541 agctaaaaca acgtctacag attctttttt agctaattca aacccttcgt ttattaattc
   123601 tacagttggg tttggctcta ctctctgaac ctcccatgac taaagtcaca gggttcctgc
   123661 ttcacagaat tttgcatact aaaatatgtc ttactaattc tccacaggcc atccccgtag
   123721 ttcctacggt tcttacataa gttatttatt ttgaattgtt attagtctta atccttcttt
   123781 taatatattt atacttgcat ttatatctct atcgtgagtt tcattacaac taggacaaat
   123841 ccattctctt atatttaagt ccttcacttc ctcgttttta tacccacatt tattgcatat
   123901 ttgtgaactt gcaaagaatt tacctacctt tacaatttgt ctaccatgcc aattagcctt
   123961 gtattctaat tgacgaataa attctgacca tgatacatct gaaattgagc gagatagttt
   124021 acgattttta atcatattct ttacttgtaa atcttctatg caaataatat cattctcttt
   124081 tattaattta gtag
//
LOCUS       DAFAZV010000009       111205 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFAZV010000009 DAFAZV010000000
VERSION     DAFAZV010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 111205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 111205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..111205
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.009"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(164..1504)
                     /locus_tag="KOU88_001007"
     CDS             complement(164..1504)
                     /locus_tag="KOU88_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK3210911.1"
                     /translation="MIKSSLFWNIFIAISFMIEWFLCKKMLDYTSEKRISNKKINFCM
                     VGIIVFADIIYFFDVPPNIRVIISMIITIAFYKISYDVGFIKSVLISLIYWMLLIATD
                     ALSISLTVWLNSINDMSSMGTGDIYRIESIILGKILLIVSLLLYRALKIKLNIEINKR
                     TLFYIVIPIVANIASFFVIFEYIFNPGSGSLIHNFQFVMISVVLLISSITLVLIAKKL
                     QQYNTLVVENNMIKNTLKYENEYYEDIEKKYLKTRLLSHDMKNHILCINAMIKKGIDV
                     TSYLNNLQVEIQSNDLLFNTGNFILDAILSEKKEVCDKNDIELKIGINFSCCEAVELV
                     DICHIFSNILDNAIEACNKIDSGNRVICVKGDVMQNFYLIRVENTKINKIITKNGDIL
                     TDKKGSLHGLGIKSVKNSVNKYGGNVVIEYDDKKFVVKIAIPLRNVKKAVNHVI"
     gene            2051..5095
                     /locus_tag="KOU88_001008"
     CDS             2051..5095
                     /locus_tag="KOU88_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBK3210912.1"
                     /translation="MKKMLKRLCTGFLALATVVTALPTTPVHAESKQYWTESAERVGI
                     IEKVMNDGSIGSTFNEGYMKVEGETAYCIDINTDFKNGYKTRADASSRMSADQISDVA
                     LSLEYVKQYGEAHKKLNYKQVYLLEQCVVWQRLSVHLGWQCDNVRASYDEIPKATQDE
                     VFSGARAFVKENKGRYECGGYIYSGEGQELGQFWAKLNVGNAKLQKTSSNTSITNGNG
                     NYSIAGATYGVFADKDCTKQLATLTTDENGNTDVAEVKAGTVYIKELSAPVGYKVDKK
                     VYPLTIKAGETATLNVSDTPKVTDTLIELFKMDMETQKDNPQGNASLAGAEFTWKYYA
                     GFYNKDNLPAEATRTWVTKTIAETDSNGTTHYITKLADAYKVSGDSFYMQDGKAVLPL
                     GTLTVEETKAPNGYLLDGAYMQAGDKSEQIKGLYVTQITEDGDLAVLTGSNQFSVSDK
                     VIRGGVKIQKRDLETGDTKPQGSATLKDTAFDIISLNDNAVLVEGKLYKKNEVVKTIR
                     TDIEGVGSTSADLLPYGKFRIVESEAPNGYLTDGAKPIDFTITENGKIVDLTDEAHSI
                     YNQIKRGDIEGVKIGAGTHKRLADVPFRITSKTTGENHVVVTDDNGQFSTSAEWASHK
                     HNTNAGKTTEDGVWFGTSEPDDSKGALPYDTYIIEEMRCESNKGFELIPPFEIVVSRN
                     NLVVDLGTLTDEYEKEISIHTTATSKDGEKTILAGKEVTIVDTVKLEGLTKGTKYQLK
                     GWQMLKEENAELIIDGKRVENDYTFVADDEEIKVEISYTFNASALGGKNLVTFEELYD
                     LSNPDEPVKVAEHKDIEDEGQTVLITERIIKIHTTATDKDGNKELEAGKKVTIIDTVT
                     LEGLEVGTQYKLVGWQMLKEENAELLINGKRVESDYTFTADSETMKVEVAFTFDATSL
                     DSKQLVTFEELYDLSNPDEPKKVTEHKDIEDKGQTITFKEKPEEPEKPETPPTPEKPN
                     RPSDSPKTGDSTNVMVFIVMLLASAGGLAGTYLYKRRKMKKS"
     gene            5330..5656
                     /locus_tag="KOU88_001009"
     CDS             5330..5656
                     /locus_tag="KOU88_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK3210913.1"
                     /translation="MEMKYVVPDMAQSFGTLEFAGESEPVFERDKNNRRVLARRSYNL
                     YSDVQKGENVVVEIPVQAGEKHFKYEQKVKLVNPKLYGRGYAIGDMGHTDYVLVADDI
                     VAVEEK"
     gene            5672..6055
                     /locus_tag="KOU88_001010"
     CDS             5672..6055
                     /locus_tag="KOU88_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK3210914.1"
                     /translation="MRLSNGFVIDKEKTFGELKFTAVRDVFLQNEDGTPSTQLKKRIY
                     DLKCSLHGGIIPVSVPPEVPLREFPYNAVVELVNPVADTVSRKTYTGADVDWYVKAED
                     IVLKNKGNQNAGNPQSHTPQGQPKK"
     gene            6131..6547
                     /locus_tag="KOU88_001011"
     CDS             6131..6547
                     /locus_tag="KOU88_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBK3210915.1"
                     /translation="MKVLVSSCIMGKNCKYNGGNNLNPKVVEFLKDKEVIEICPELLA
                     NMPTPRPSAEIVNGIVMDINGNIVDEEYRHAVQLALNEIRSMEIDLVILQSRSPTCAV
                     KNIYDGSFTGKLIKGQGLFAQALIEAGYKVLDSEDF"
     gene            6621..8003
                     /locus_tag="KOU88_001012"
     CDS             6621..8003
                     /locus_tag="KOU88_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009290090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210916.1"
                     /translation="MRKIWNKGHRIRASDKHLVYHFSIGTLLFVFVAVLLLLNSKQLM
                     RTDWEHFSLLENGLTLSPYNFITILIATGVCALVAFGYYRICYDHFKKLLHRQKLARM
                     VLENKWYEADTVQDSGFFTDLQSRSREKIVWFPKIYYQMEKGLLHIRCEITLGKYQDQ
                     LLRLEDKLESGLYCELTDKTLHDGYIEYTLLYDMIANRITIDEVRAENGSLRLMKNLV
                     WEYDALPHALIAGGTGGGKTYFLLTLIEALLHTNAVLYILDPKNSDLADLGTVMGNVY
                     HAKEEMIDCVNAFYEGMVQRSEEMKRHPNYKTGENYAYLGLPPCFLIFDEYVAFFEML
                     GTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFGDGMRDQFNFRVGLGRISEL
                     GYGMLFGSDVKKQFFQKRIKGRGYCDMGTSVISEFYTPLVPKGHDFLQTIGRLAQERQ
                     VMPEQQGKEN"
     gene            8007..8399
                     /locus_tag="KOU88_001013"
     CDS             8007..8399
                     /locus_tag="KOU88_001013"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210917.1"
                     /translation="MKELEIYNIQTRRMMKYVCFHYEQFEADCDKLTVERYKNFTVNP
                     KNRFETRMEKVTEQLLSGERVIPSRLCLRLENRHSICNCRIDYVFEIFDMKSLREDIR
                     KEDFSAEEWITCEKSNVDYVLIYIGMNK"
     gene            8625..9821
                     /locus_tag="KOU88_001014"
     CDS             8625..9821
                     /locus_tag="KOU88_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBK3210918.1"
                     /translation="MVLNEEQWIKELREKRIAYGISQGRLAVASDITREYLNKIESGK
                     MKPSKELLETLHKELARFNPEAPLTMLFDYVKIRFPTLDIQHIIKDILKLNINYMLHE
                     DYGHYSYTEHYSLGDIFIYTSADEEKGVLLELKGRGCRQFESYLLAQQRSWYDFLMDA
                     LVNGGVMKRIDLAINDHTGILDIPELAEKCRKREYIGKFRSYKFYQSGELIKHREDDR
                     EYMGRTLYLGSLKSDVYFCIYEKDYEQYVKLGTPLEKAEIINRFEIRLRNERAYYAVR
                     DLLTYYDAEQTAFSIINQYVRFVDEEPDKRKNDWKLNERWAWFIGDNRQSLKLTTKPE
                     PYTLDRTLRWVQRQVAPTLKMLKRIDKGNGTDYMKTIEQQAKLTEKHEMIIKQQTTPA
                     KDLVES"
     gene            9835..9969
                     /locus_tag="KOU88_001015"
     CDS             9835..9969
                     /locus_tag="KOU88_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBK3210919.1"
                     /translation="MWELLKDFLLVSVGTGIGVALMCILSVGKEADYEMKKLKESEDK
                     "
     gene            9971..10192
                     /locus_tag="KOU88_001016"
     CDS             9971..10192
                     /locus_tag="KOU88_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210920.1"
                     /translation="MNFGQNLYQWFLSNAQSLVLMSIVVIGIYLGFKREFSKLIGFLV
                     VALIAVGLVFNAGGVKDVLLELFNKIIGA"
     gene            10227..10868
                     /locus_tag="KOU88_001017"
     CDS             10227..10868
                     /locus_tag="KOU88_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3210921.1"
                     /translation="MWIYKILIYGGILLKKAMIYVHGKGGSYLEAEQFKNICLDFDVF
                     GVDYNDYFPWIVKNEIMEVYDKISEKYDYIYVLANSIGAYFTMHTLQNFKIEKALFIS
                     PILDMEQLIVDMMSWANVSEKELSERKEIPTDFGETLSWEYLCFVRENPINWKTPTEI
                     LYAEHDNLTSRQTVDKFIDRHCANLTVMNDGEHWFHTNEQIFFRDNWLRKVIQ"
     gene            10957..11253
                     /locus_tag="KOU88_001018"
     CDS             10957..11253
                     /locus_tag="KOU88_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005339688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210922.1"
                     /translation="MSDIFKDMQANVGCDYISNLPSYKRKVWHEMKRLPLTNYDIKQL
                     EDFSKYVFGMSYQSLKDVMKQQKGREEQCRKQGCWWKREEQLAKKQHHTGSTYR"
     gene            11172..11675
                     /locus_tag="KOU88_001019"
     CDS             11172..11675
                     /locus_tag="KOU88_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK3210923.1"
                     /translation="MQETRVLVETRGTTGKETTSYWFDLPIDVAEFEEKLGVGAESQD
                     YRIIEKVLPYADEVHEQTSVYQLNELDFMYRQLPADMQEEYIALLTVFENLEALYICR
                     NVITVYPDCKSMIDVAKQKLMNDPTFKHLSEDCQAYYFDFEAYASHLLENRRYLVTEH
                     SVFELPA"
     gene            11693..12196
                     /locus_tag="KOU88_001020"
     CDS             11693..12196
                     /locus_tag="KOU88_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK3210924.1"
                     /translation="MIDDMAVYIANLGKYNEVYLVGAWFTFPIDEEDVKEKIGLNEQY
                     EEYAIHDTDNFPIAIGEYVSIDELNEMYEMLEELPDYIVECLDEFIGHYGTLEEVVEH
                     KDDIYYYPDCETMTDVAYYYIDELQALGDIPPSLQNYIDYEAYGRDLDIGGCFIETSR
                     GMCEIPY"
     gene            12315..12713
                     /locus_tag="KOU88_001021"
     CDS             12315..12713
                     /locus_tag="KOU88_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210925.1"
                     /translation="MKKIKSYTGIWNVEKVLYAINDFNLPFPVTFTQITWFVITEFII
                     ILFGDMPPLSMIEGAFLKYFGIPALLTWFMSQKTFDGKKPYSFLKSQITYTLRPKITY
                     AGKAVKLHKQILNETITAVRSVNDVPDKIY"
     gene            12691..15141
                     /locus_tag="KOU88_001022"
     CDS             12691..15141
                     /locus_tag="KOU88_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3210926.1"
                     /translation="MFPIKYIDNNLVWNKDNEVFAYYELIPYNYSFLSAEQKFIVHDS
                     FRQLIAQSREGKIHALQIATESSIRSMQEQSKKLVTGKLKEVAYQKIDEQTEALVSMI
                     GDNQVDYRFFLGFKLMVTEEQLNLKNIKKSTWLTFKEFLHEVNHTLMNDFVSMPNDEI
                     NRYMKMEKLLENKISRRFKVRRLEIHDFGYLMEHLYGRDGVAYEDYEYQLPKKNYKKE
                     TLIKYYDLIRPTRCVIEESQRYLRLEHEDKESYVSYFTVNAIVGELDFPSSEIFYFQQ
                     QQFIFPVDTSMNVEIVENRKALTTVRNKKKELKDLDNHAYQAGNETISNVVDALDSVD
                     ELETDLDQSKESMYKLSYVIRVSAPDLDELKRRCDEVKDFYDDFNVKLVRPAGDMLGL
                     HSEFLPASKRYINDYVQYVKSDFLAGLGFGATQQLGETTGIYMGYSVDTGRNVYLQPS
                     LASQGVKGTVTNALASAFVGSLGGGKSFCNNLLVYYAVLFGGQALLLDPKSERGNWKE
                     TLPEIAHEINIVNLTSDKDNAGLLDPFVIMKNVKDAESLAIDILTFLTGISSRDGEKF
                     PVLRKAVRSVTQSENRGLLHVIEELRKEDTAISRNIADHIDSFTDYDFAHLLFSDGTV
                     ENAISLDNQLNIIQVADLVLPNKDTTFEEYTTIELLSVSMLIVISTFALDFIHSDRSI
                     FKIVDLDEAWAFLNVAQGETLSNKLVRAGRAMQAGVYFVTQSSDDVSKESLKNNIGLK
                     FAFRSTDINEIKQTLEFFGIDKDDENNQKRLRDLENGQCLLQDLYGRVGVVQIHPVFE
                     ELLHAFDTRPPVQRNEVE"
     gene            15141..17339
                     /locus_tag="KOU88_001023"
     CDS             15141..17339
                     /locus_tag="KOU88_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK3210927.1"
                     /translation="MKERLKGLLTKRKLFHFVKVAVLAIFISIVFLSLLGTVAHATGL
                     VDDTVNTENLYSKYPLSNYQLDFYVDNSWGWLPWNWLDGIGKSVQYGLYCITNFVWTI
                     SLYLSNATGYVVQEAYKLDFINDMADSIGQSIQTLAGVTENGFSSTGFYIGFLLLIIL
                     VVGIYVAYTGLIKRETSKALHAVINFVVVFVLSASFIAYAPDYIKKINEFSSDISTAS
                     LDLGTKIMLPNSDSEGKDSVDLIRDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEALV
                     SASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFLLT
                     GMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTVAF
                     SISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFRRL
                     YLFMRHRARRMEHRIARTVSAGGVAGAAAGSAVAGKRAERKNTASKENRSNTTSSMGQ
                     RAGSKVGAVLDTKNKVKDKANAVKENIKDMPTQTAYAVYSAKEKAKSSVSDFKRGMVQ
                     EQQSRQTGRLEKQEQRKKNIADKRMELQKAQEVRQAQRKADGSATTGATRPHERPATA
                     STIPKPSAEKMQEVKRPATALTSKASEPVKTNVIKERPLSSGASDRKATQSAQPVHRQ
                     NVEKVVSQETRQNDTKDRRIKVQQTQSVQKNQQTTEKSRNLVTKKGQKKK"
     gene            17336..18343
                     /locus_tag="KOU88_001024"
     CDS             17336..18343
                     /locus_tag="KOU88_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK3210928.1"
                     /translation="MKLKHIALIGSLFPILFSLVLFFGVLISADSDDENSNFSSSITG
                     MNLSAEVLKHQPMVEKYARENGISEYVNVLLAIIQVESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSSCKNQGMDDLNVAIQSYNYGGGYVGYVAGNGKKHTYNLA
                     ESFAREKSGGKKVTYTNPIAVAKNGGWRYQYGNQFYVELVNQYLTVPQVSGELTQKVM
                     NEALKYQGWKYVYGGSNPNTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGTYVTHVGILVSPTQMYHAGNPIGYADLSSSYWQQHLIGAGRIK
                     Q"
     gene            18360..19271
                     /locus_tag="KOU88_001025"
     CDS             18360..19271
                     /locus_tag="KOU88_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3210929.1"
                     /translation="MFKKNKKQTETIKEPKEKKVRTVKVGTHKKTVIALWVVLIASVS
                     FGVYKNFTAIDQHTTHEKEIIELRLQDTNGIKNFVKNFAKSYYTWNNSKEAIEARTQA
                     INGYLTKELQDLNVDTIRTDIPTSSTVTDVIVWNIEQSGTDTFSATYEVDQQIKEGEQ
                     TTAIKATYTVKVHVDADGDMVIVQNPTLAPAIEKSDYEPKTPEADASVDADTVNDATS
                     FLETFFKLYPTATEKELAYYVSGNVLEPIGRDYFYSELVNPIFTKDGDNVKVKVAVKF
                     LDNQTKATQVSQYELVLHKDNNWKIVG"
     gene            19413..19649
                     /locus_tag="KOU88_001026"
     CDS             19413..19649
                     /locus_tag="KOU88_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008791134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBK3210930.1"
                     /translation="MMKKGQHIFGTVKVGERGQIVIPKEAREIFDINAGDTLLVLGDE
                     EQGIAIVKADVMKELAVKILKGLGSLSGGFNDEK"
     gene            19639..20256
                     /locus_tag="KOU88_001027"
     CDS             19639..20256
                     /locus_tag="KOU88_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005951992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBK3210931.1"
                     /translation="MKNSISLFLPLALLLDLTIPFFLAPFYKGYSHSMQVMSVLGNNK
                     SPLHFIYNLWLVLCGIILLMSGFKVYEIVSQKSKNIAVILFIVILIYAIGGCILSGIF
                     SVGETKSLNTIPEKIHGYGAVLRFICLTFAPLLISLYWFRIEEIPLALFSMICFLLAF
                     IFFTIFVMADKPNYKDTIIAFEGLWQRLSLLFMYLPLGCLILLEK"
     gene            20276..20512
                     /locus_tag="KOU88_001028"
     CDS             20276..20512
                     /locus_tag="KOU88_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210932.1"
                     /translation="MIGLKKRDIKKALRAGAKAGGMSLADVRADIEATIDEAMNSTDP
                     EVQANFKKNFGNKRPAPEEYIYIITKKTVKGLKV"
     gene            20509..21481
                     /locus_tag="KOU88_001029"
                     /pseudo
     CDS             20509..21481
                     /locus_tag="KOU88_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014519979.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
     gene            21494..22108
                     /locus_tag="KOU88_001030"
     CDS             21494..22108
                     /locus_tag="KOU88_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBK3210933.1"
                     /translation="MKKVYVYLLDDMAECEIGYILQAFSMEKLLKNGTKEFEVKTVGF
                     NKEPVLTLGGLTIVPDYSISEVDFNASTALLLPGSSTWGSKENQEILEKAQECLNKNI
                     LVGAICGATLALADYGILDKFKHTSNSLEYLNFFSRNYAGQSLYVCSNSVLDRNLVTA
                     NSAGSLEWTKNILNYLNVYSDNKITAFYNYYSTGNAKYYDELLK"
     gene            22136..22309
                     /locus_tag="KOU88_001031"
     CDS             22136..22309
                     /locus_tag="KOU88_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013485815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBK3210934.1"
                     /translation="MGIMPICNNKTRTKIRVDTELISFPLFCPKCKHETLINIKHGNV
                     TTIKEPDAKTQSR"
     gene            complement(22545..22796)
                     /locus_tag="KOU88_001032"
     CDS             complement(22545..22796)
                     /locus_tag="KOU88_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009245175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210935.1"
                     /translation="MKLFIGDIIQKLRKIKGLTQEQVANALGITTSSVSKWETNNTYP
                     DISLLSPLARLLGTAVDNVFNFKQKLSEEEIDTLLNRSK"
     gene            23061..23765
                     /locus_tag="KOU88_001033"
     CDS             23061..23765
                     /locus_tag="KOU88_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011098902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK3210936.1"
                     /translation="MMKAILKTNNLCKDFKKQKAVNNVSITVRENSIYGLLGPNGAGK
                     STTLKMITGMLRPTSGKVLFNGHEWNRKDLEQIGALIETPPLYENLSAVENLEVRAKL
                     LNIPKTRIDKVLKMVDLQNTGRKKAGQFSMGMKQRLGIAIALLNSPKLLILDEPTNGL
                     DPIGIQELRSLIRSFPSKGITVILSSHILSEVQLIADDIGIISNGILGYEGQMNKDEN
                     LENLFVEVVRKSQEER"
     gene            23767..24510
                     /locus_tag="KOU88_001034"
     CDS             23767..24510
                     /locus_tag="KOU88_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018597933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBK3210937.1"
                     /translation="MKNYISSEYLKHKNTFAKKLVWLAPILTLCLNILAPMWYQQNSY
                     NWWYVFLYPGCLTLLSILIIQRDNGKLKFRAILSLPVDLKKVWYAKIITCIIYIVLAN
                     TILMLCNVAGGFIIQHIFDIPMTISPMQALFGTLCIILASIWNIPLCLWFTKKVGVFA
                     TLILNVGMSFMLGTLGANTSFWFICPYSWVTRLMVPTLGILPNGESVTGSALSTPLPL
                     VIMTICLSLLLLYTISKSTAKSFIKQEVL"
     gene            24510..25253
                     /locus_tag="KOU88_001035"
     CDS             24510..25253
                     /locus_tag="KOU88_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008705324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBK3210938.1"
                     /translation="MFSIIRCFQAEWLKSRHTPLLLVHVLFPLIGAGVFAGYFHISGW
                     SEMTNVTTFLEVLAIIFPFVIGIVVGMIVELENGAGHFQLILGTIRSRIAVYIGKLVY
                     LIVLATFATILCIFLFAVLYPVMPFSFYIKPLIMLILSVIPLYLISIPVGFSLGKSVS
                     MGIGIVGSLLSALLVTGLGDFIWKFLPWGWGVRFMDYCVLRYVNEGQFHSNLPEFQLG
                     FILMLVFTVVLFIISLVWFQRWEGVKENE"
     gene            25246..26055
                     /locus_tag="KOU88_001036"
     CDS             25246..26055
                     /locus_tag="KOU88_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NisI/SpaI family lantibiotic immunity
                     lipoprotein"
                     /protein_id="HBK3210939.1"
                     /translation="MSKKMMILLFAVIICLSLAGCSLQDKIGDYSREQCYLNKENVTQ
                     FSYKGNDYTILADTVSNSGLGEWIGYIRQLAAVDESGKILLQENLKTATFQTLADLAD
                     LVDKAPNDAYIIPFLNVYAAPNADDYLIVDINGGYHKAVIDENIKGTDTVFDFKDIEQ
                     SMSGKFEINPQNATQLLCDGTVYQVTSDTVSNNELGSYIGILAENVIFNAETKIPLSK
                     EELRKIDWYGENAGQHREQWIYKDIYEIHGTEKTEAVAVQINDRYYIAKRQ"
     gene            26118..26777
                     /locus_tag="KOU88_001037"
     CDS             26118..26777
                     /locus_tag="KOU88_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005423211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210940.1"
                     /translation="MATILMIDDERPILELVKNGLQKDGHLVTVYTSAAQVPLDKLNR
                     YDLIILDIMMPDIDGFSYCDKIRSLVDCPILFLTAKTMENDITFGLGLGADDYLTKPF
                     RITELRARVNAHLRREHRERHIALTFDRIKIDLSAKELRVDNIPVPLTKSEYLICEYL
                     ASNKGQVFSKEQIYEATFSLYGESDSSTISTHIKNIRSKFEKTGVQPIVTVWGIGYRW
                     E"
     gene            26768..28132
                     /locus_tag="KOU88_001038"
     CDS             26768..28132
                     /locus_tag="KOU88_001038"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012722.1,HMM:NF014567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3210941.1"
                     /translation="MGIKMKTSLTRTFYKFLVCLLGGLCLSVVVPFACMMFASSIGLV
                     TLADNNERQTKALVPILTATPNVSDIHFPTGTKFLRLTKNYGYIDTNMSEEEKEKALM
                     FAKTGFMDTSGKTQFIFITRDDEYIVLQYVIGSQYLNAQFNQYLPSPEIMMISLITIS
                     SLGVCVYLTVHFAKELRKELTPILEATKEIENNNLDFTIGHSKILEFENVIISFDSMR
                     NSLKGSLEKQWRSEKAQREQIASLAHDLKTPLTVMQGNIDLLDETELDEEQKLYLSYA
                     MSSSEQMKQYIKILIDISKASAGYQLQMEDVNFPEFWKHVLSQTEIICKDKGIVIQQT
                     QHNFPQNITGDRMLLERALMNLVSNSLEYSPENSTLYIDVDSKDNYLNICITDCGCGF
                     SQEALDHAKERFYMADQSRSSKLHYGMGLYIVDIIIKQHKGKLLLDNSTETKGAKVTV
                     KLPL"
     gene            28493..28912
                     /locus_tag="KOU88_001039"
     CDS             28493..28912
                     /locus_tag="KOU88_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3210942.1"
                     /translation="MKPSDFQKTIQCQFECKLKKVTKGIVRNYQKELKRRKNKEIPFC
                     ELPELVIEKLSVLDDYDSDYTLFNVCGNDISILDDELAEALKKLSDRNRENLLMYYFL
                     EMSDTEIAKLQNISRSGVFQNRYNSLELMKKILKGEK"
     gene            28916..29164
                     /locus_tag="KOU88_001040"
     CDS             28916..29164
                     /locus_tag="KOU88_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004613734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3210943.1"
                     /translation="MKHIFKKPSFYLISSATDGDEKAIEKILAIYDPYISKCCLRSLY
                     DEYGNVYIAVDMELKGRIREALIKMILDFDIPLETEEE"
     gene            29540..29743
                     /locus_tag="KOU88_001041"
     CDS             29540..29743
                     /locus_tag="KOU88_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBK3210944.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKLAEENIDAGWVI
                     VNGNRIQIKRKQFEKIIDTLDEI"
     gene            29822..31012
                     /locus_tag="KOU88_001042"
     CDS             29822..31012
                     /locus_tag="KOU88_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009271880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK3210945.1"
                     /translation="MSNVKRKDSKNRNLRNGESQRKDGRYVYKYTDIYGKPQFIYSWK
                     LVPTDKTPAGKRDDISLREKEAQIKKDLNDGIDTVGGKMTVCQLYEKKNSQRKNIKRA
                     TEKGRQYLMNALKNDLLGMRAIDTVKQSDAKEWAIRMSEKGYAYKTIDNYKRSLKASF
                     YMAIQDDCIRKNPFEFKLSDVLEDDTEQKVILTPEQEKHLLAFMETDKIYSKYYDEVV
                     LLLETGLRISEFCGLTTHIDMQNRILNIDHQLLKDSEMGYYIETPKTKNGKRELPLTE
                     RAYQAIQRILENRGKAQPLIVGGYSNFLFLNREGLPKVAGNYEGMVRGLIKKYNKYHT
                     DKLPNITPHSFRHTYCTNMANRGMNPNTLQYLMGHANITMTLGYYAHGTFQSAKAELE
                     RLAC"
     gene            complement(31600..32691)
                     /locus_tag="KOU88_001043"
     CDS             complement(31600..32691)
                     /locus_tag="KOU88_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBK3210946.1"
                     /translation="MIEKVEEKSKIIKTSKEYKRTIIEEKDKEWTKKLNDILSRSSFS
                     NDELDKIKALIPKEILTNENVGEVVTEDGYAKPEYDEVFKSLFTLNNEYDLLVNFIND
                     ILKDAPYANRNIKPFTQIKRIIRVETDPTINYIGEKRPKLDILAEDEENNHINIEMQR
                     AFENDYLERAEYYLSRVHGRKLEEGKEYKEIGKTIGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIYSSKTALYFIELPKIHKSDYIVNRIMLWGKLISNPSNLDVRVIAKNDSIIK
                     KALDRLKELGSNEEYLLNLKRGAYIMNKSRNFKEEIERETAIRVAKEKDYKIIIMLKK
                     NGFKLDDILNKFNDFDLSEDEIKEVYENN"
     gene            complement(33459..35378)
                     /gene="thrS"
                     /locus_tag="KOU88_001044"
     CDS             complement(33459..35378)
                     /gene="thrS"
                     /locus_tag="KOU88_001044"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBK3210947.1"
                     /translation="MIKVALKDGSIKEFENAISVMDVAKSISEGLARNVVAASVNGEV
                     VGLDHIIDTDCDLNLFKFEDKEGKEVFRHTSAHILAQAIKRLYPEAKLAIGPSIENGF
                     YYDIDLDHRLVPEDLEKIEAEMKKIAKEDLKIERFELPRNEALELMKEQGEDYKVELI
                     SDLPESEIISFYKQGDFTDLCRGPHLPSTKKVKAVKLQSVAGAYWRGDENNKMLQRIY
                     GTSFEKNKDLEEYLHLLEEAKKRDHRKLGKELGLFMIPEEGPGFPMFLPKGMELKNEL
                     LKFWREIHRKAGYIEIESPIILNRKLWETSGHWYHYKENMYTVKIDDEDYAIKPMNCP
                     GGLIYYNSQLHSYRDFPMRVAELGRVHRHELSGALQGLMRVRAFTQDDSHIFMLPEQI
                     KDEIKGVANLIDGIYKTFGFEYNLELSTRPENSMGSDEEWEAAENGLREALEELGLPY
                     TINEGDGAFYGPKIDFHLKDCLGRTWQCGTIQLDMQLPRQFDNTYIGQDGEKHRPVMI
                     HRVAFGSIERFIGILIEHYAGKFPVWLSPTQVKILPISDKFMDYANEVKKELFDKGIR
                     VELDDRAEKIGFKIREAQLEKVPYMLIVGEKEVADNNVSVRSRDKGEIGSIKLDEFIA
                     SISKEIESRESIIQD"
     misc_binding    complement(35442..35680)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(36292..36894)
                     /locus_tag="KOU88_001045"
     CDS             complement(36292..36894)
                     /locus_tag="KOU88_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 family protein"
                     /protein_id="HBK3210948.1"
                     /translation="MDNLIRILILAVIGGFIGYVTNVVAIRLIFRPIEPIKIPILNIE
                     IVGLIPKRRAEIAANVGEIIQEEFLSMDEILANIITDEDKEEVVRYIKARVKIIIHEK
                     VSFIPSGIKNMIQDYLGEIIESEVKQSIDELSKNIINKANERIDIQKMVEDKINELDL
                     YELEEIIIRIAKKELKHIEFLGLVLGFLIGIAQGLITMFI"
     gene            complement(37074..37892)
                     /locus_tag="KOU88_001046"
     CDS             complement(37074..37892)
                     /locus_tag="KOU88_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sporulation protein YtxC"
                     /protein_id="HBK3210949.1"
                     /translation="MVEKDNISSMKFLRNNNVNDRLIYTNDIVEVVIDSAKQEVLNKK
                     ILNGTKAEQRALNIDEISTEITSMIISIMKEKLLKEYILKCYGRTYPEDKNNIYIYSL
                     NIFAKKEIFMRETVFTRVRNYIEENDFINVEGFIRFRMREFMKYISAIGDIAVEEYLI
                     KKDQDEFIRVLKYFIDTQEEKIDLLKVHIMEDNTFVLYDKNGNKIDSIDDEEIINMVI
                     RENLNYEDFLISTLLTLCPKKIEILDLLNNNCSKEIIDTVEAIFENKVSIIMEN"
     gene            complement(37895..38656)
                     /locus_tag="KOU88_001047"
     CDS             complement(37895..38656)
                     /locus_tag="KOU88_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210950.1"
                     /translation="MEFTREPFILDDDLCLALVDKRISYLMENELKLRNIEIIKTIEC
                     KELYESIKYHPDICICNLGKGDIIVAPNVYNQYKELLSRYKFNIIKGEANLLNRYPYD
                     IPYNIAIVGDYAIHNFKYTDKAILDYIENNKLKKINIEQGYSKCSICIVDRTSIITSD
                     KGIWKSMKNTEIECLLIEKGHINLFEMNYGFIGGCTGLISKDKLAFCGDVKKHPDYER
                     IKSFVESKNKEIVTLSCENLLDIGSIVPLMTRKER"
     gene            complement(39146..40258)
                     /locus_tag="KOU88_001048"
     CDS             complement(39146..40258)
                     /locus_tag="KOU88_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3210951.1"
                     /translation="MKIKRILMACFVVVFTIFILAICNFDFGFDKVNKNNSNIDSAKS
                     KQSESKSLLTSAEKDKSNSKSKNKEDDTEDDSYVRKTIGVLLDTENLNNESYNNNVLS
                     ALKRADEDFDVRIKLEKPKTSKSFKESIEKLHKYEPDFIIAVGARFAEPIKEAATKYP
                     KQQFAIVDYTYKVQPANVISVSFQDNVTGYLAGLIAGKMTDTGKVGFIGGVEGSSRDK
                     YESGFRKGLKTSNKDAELLVKYSNIFENPESARTIAKEMRDSDRDVVFSATEDDSKRA
                     IQVARENGGKVIAINKDQYDMAPDNVISSIIKDVEQPVYELIKNVAKDGFKGSKVMEF
                     KIKDGELGLTSKSSRNIPPDVLEYIKKEYNKVKDTY"
     gene            complement(40384..41388)
                     /locus_tag="KOU88_001049"
     CDS             complement(40384..41388)
                     /locus_tag="KOU88_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3210952.1"
                     /translation="MRFKRILILMLTVAMIAGMLVGCANNPSNNPSSSKDNKSDISDK
                     SNSKKSVSMILDIEGTNNEAMNNSALLALNNAQKKLNIDTNKVESDDSSTFSNSIDIL
                     CNDNYDLIIAVGARFAKPLEMVAKKYPKQQFAIIDYEYDKQPSNITSISYEDNKSGYL
                     AGLIAGKMTESDKVGFMGGTKSSSRDKFESGFREGVKFSNSSIKDISVEYADVFKDSK
                     SVESIAKKMMDNGVDIIFSTTEDDSKAVIDAVRAKNKKVIATNKDQHELAPENVISSI
                     VKDFENPTYNLIQSFVKGNYKGGKVIENTVKSGSTGLAQNSSQNIPPDVLEYVNKNNK
                     "
     gene            complement(41676..42524)
                     /locus_tag="KOU88_001050"
     CDS             complement(41676..42524)
                     /locus_tag="KOU88_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK3210953.1"
                     /translation="MKNLKIICDSLSDVPKDLLDKYDIDIVSLTVILEEREYKDRIDI
                     SGDEFYKRLREENVYPKTSQATYAQFKEIFEKYTNEDREILYIAGSATATGTYQSAVM
                     AKNDVDGKIYTYDSNLLCMGTGLLVIKAGELASEGKSVAEILPVLDELKEKAFVIFSV
                     DTLEYLQKGGRISSTKAAIGSILNIKPILEIRDGLVSQISQVRGKKNVISKMMELIKS
                     NCGDDLSDQIVYIGYSDDFKEKEQLSKVMQDELRPKEIRFFQIGVCIGAHAGPGVTGI
                     ICLKNK"
     gene            complement(42560..43030)
                     /gene="trmL"
                     /locus_tag="KOU88_001051"
     CDS             complement(42560..43030)
                     /gene="trmL"
                     /locus_tag="KOU88_001051"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBK3210954.1"
                     /translation="MSLNIVLVEPEIPQNTGNIIRTCAATGSTLHLVKPLGFSLDDKH
                     LKRCGLDYWDIADIQYYDSFEELQEKYPNSKYFFSTTKAKQSHSDVKYEENCFIVFGK
                     ETKGLPEPLLKANMDTCIRVPMLDVEKARSLNLSNSVAIVVYEALRQIGYPNMR"
     gene            complement(43224..44393)
                     /gene="nth"
                     /locus_tag="KOU88_001052"
     CDS             complement(43224..44393)
                     /gene="nth"
                     /locus_tag="KOU88_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBK3210955.1"
                     /translation="MKNVNLKEINEKDVILEEEINKKGMDKKNIIEKEEINKKGIDKK
                     DIIEKEEINKKGIDKKDIIEKEEINKKGMNKKDIIEKEEINKKGMNKKDIIEKEEINE
                     KGIDKMIGKKDEIIDEKDIENFMDIEEDKKSIKVSKKSTKKGETEKKTKKSSSNKATQ
                     KTSKETKSKSKIKNESANEKDVNKILDELEKLYPDAKCELNYGTAFELLIATILSAQC
                     TDVRVNKVTSELFKKYNTARDFANLSIEEISKEIKSCGLYKSKSQKIKDTSEQLCELY
                     DGEVPDSLEKLIKLPGVGRKTAGVVLSNAFNHPAIAVDTHVFRVSNRIGIVDEPNPQK
                     TEFALMEAIPKERWSHSHHVLIFHGRRMCKARNPECASCPIKEDCNYYKELNETK"
     gene            complement(44591..46828)
                     /locus_tag="KOU88_001053"
     CDS             complement(44591..46828)
                     /locus_tag="KOU88_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3210956.1"
                     /translation="MKYNNTSEINPLDYILGQERAVEAMELGLKINNPAYNIYIAGEP
                     GTGKSTYALKVLNEYASKKNTHKDWCYIYNFENPREPIIVELEKGFGRELKKDMEKLI
                     ESLLEDFKNAFESENFEIEKNKLLDEYEIEKDMLLKQIKKYGEEKGFKLKQSKMGIVF
                     IPLKEEEDESDESDEEFYKAKRELENMAIQVVYKIRNLEEIAEKAVLELEEEIAKLVV
                     EPHIKRLCEKYENYDKIQTYLENIKKDIIEYMYLFYLDEEELKDKYDKEHFIKYKINL
                     FVDNGSSKNKESAPVVVEINPSPANLFGKAEYDYANGNIKTDFTKLLSGAFHRANGGY
                     LVLYADQLLKYTMSWEILKKTLQTKKVILETQTAIKPENMPLDVKLVLIGSHYIYDIL
                     YRYDEDFEKYFKVFVDFDSEMDKNEDNEEGIARFIAYQCDKNNLRHFTKSAVEEVIKF
                     STRLSGDLEKLSTKFNKIMEVVIEGSAYAEFRNSEYTEQCDVKKAISEKRKRINRVET
                     HMDESIENGFTLIETEGRKVGVINGLSVLSTGEYSFGRASRITATTSPGSKGIVNIER
                     EVNMSGSIHNKGVLILGGYLSENFAQDLLLSLNAYVCFEQNYGGIDGDSASSAELYVL
                     LSSLSGVSIKQNIAVTGSINQKGDIQVVGGISEKIEGFYSICKTKGLNGEQGVIIPRK
                     NQRNLVLSDEVNDAVRDGKFKIYTVERVEEAIEILTDVKFEEIKKLVKEKLISFSKIQ
                     TVSKE"
     gene            complement(46934..47848)
                     /gene="queG"
                     /locus_tag="KOU88_001054"
     CDS             complement(46934..47848)
                     /gene="queG"
                     /locus_tag="KOU88_001054"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBK3210957.1"
                     /translation="MDNKELKAFCNLIGLNCVGVAGVDKYDNLEKILKDRQQKGYLTG
                     MEEPIIENRINPRHIMKDANSIIVCAFPYHINRQEKNKNSNLSKYCHGKDYHIVVKDF
                     LQQICDYISKTVTDFKYKLFADNGPLVDRYLAYLSGIGYFGINNNIITDEYGSYVFIG
                     YIVNNYKFEEDKPLEKSCFKCGKCVKYCPGNAILGNYDMNPKKCLSYITQKKGDLSEK
                     EKVVLKNGKKVFGCDICQEVCPHNVEIPTTHILEFKENIIDYLNYDEIQNISNKEFKR
                     KYGDRAFSWRGRNIIKRNMEIILDKYDD"
     gene            48870..49274
                     /locus_tag="KOU88_001055"
     CDS             48870..49274
                     /locus_tag="KOU88_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBK3210958.1"
                     /translation="MIKITIPGRPISKSNFKLHNINGQAWMPSKGKYSKYLAYENMIA
                     GFINQQYQGETVEENLITVLKLFFPNKRMGDLHNYPKSICDGIEKSGIIKNDKQLKPV
                     LLFDFIDKDNPRVEIELYPVSKYDISYNIFEK"
     gene            complement(49531..50526)
                     /locus_tag="KOU88_001056"
     CDS             complement(49531..50526)
                     /locus_tag="KOU88_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK3210959.1"
                     /translation="MRNLGNTNMKIKRVGFGGIPIQRITQDDTNLVINELEKQGINFI
                     DSARGYTISEEAIGIAIEGKRDKFFLATKSMSRDYDSMKRDVEISLNNFKTDFIDLYQ
                     FHNVKEEEYDNLFKDKMAYSALLEAKEQGKIKHIGITSHNLNTIEKAIEDGKFDTIQF
                     PYNIVEGQADEVFKKAHEKGIGIIVMKPLAGGALDNATLAIKYILSKEYIDVVIPGME
                     SVEQVRQNVAVLENLVLDEKDNKEIEEIRNSLGKKFCRRCEYCMPCAVGINIPLSFLC
                     EGYYTRYGLKEWAKEKYEVMDVKPTECIDCGLCESRCPYELPIREMLKTVVEKLG"
     gene            complement(50810..51646)
                     /locus_tag="KOU88_001057"
     CDS             complement(50810..51646)
                     /locus_tag="KOU88_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBK3210960.1"
                     /translation="MIKLGTHLSIAKGFANAAETAVYIGANTFQFFSRNPRGGNAKEF
                     DEKDIIKFQEIRKENNFAPLLAHAPYTMNLGGTKDDVYEFATRVIDEDIRRMDLLGIE
                     YMCFHPGSHVGGGVDFGIDRIVKGLNNAIKGDENITILLETMSGKGTEIGFKFEQLKS
                     IIDKIEHKEKIGVCLDTCHIFSAGYDIVNDLDGVLEEFDKVIGIERLKTVHLNDSMMP
                     FGDKKDRHAPIGEGKIGLKALIDFMEHPSLKHLPFFLETPFDDEGHKRELKMIKEILS
                     SK"
     gene            complement(52134..52697)
                     /locus_tag="KOU88_001058"
     CDS             complement(52134..52697)
                     /locus_tag="KOU88_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3210961.1"
                     /translation="MKEVLVLRDLECIKAIAHPRRIDILKAFDKSPLSAKQLSQLLEE
                     PHAKINYHIKMLYKVGILELVEEKIKSGIVEKYYYPSAKNVVIGNRILNFSLDNGEEK
                     EELYISKFENMSEVFYKAAEEDVLENENIVDYHDISLTHDELVELSDTMKSKIDEILN
                     KRQHNVEGSKYDIAMVIVPTLEEECPS"
     gene            complement(52795..53724)
                     /gene="glsA"
                     /locus_tag="KOU88_001059"
     CDS             complement(52795..53724)
                     /gene="glsA"
                     /locus_tag="KOU88_001059"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBK3210962.1"
                     /translation="MNTLDETLLKEIISSNKKYTNYGQVASYIPELKNARRNDLGICI
                     IDSENNLYSAGNCSTKFTIQSISKPIVLAMALMDNDWEDVFSNVGMEPSGDPFNSIMK
                     LEINDTKKPCNPMINAGAIVTTSLINGSCLEEKEERMLSFFRKLAKNDNIGINYDVYK
                     SEKMTGDRNRAMAYLLKSDGFIRGNVEDVLDLYFKQCSIEIDSVDLARIGINLANYGV
                     DIENGEHLMSEMVSRIVKTFMMTCGMYDASGEFAIKVGIPAKSGVGGGIMASVPGRMG
                     IGVYGPALDKKGNSVAGVKVLEELSNKLKLNIF"
     gene            complement(54715..56382)
                     /locus_tag="KOU88_001060"
     CDS             complement(54715..56382)
                     /locus_tag="KOU88_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside kinase"
                     /protein_id="HBK3210963.1"
                     /translation="MKKINLKIEGKDKEYSLEENSPGIRLGDIAKEFCDEHKGYITLA
                     VVDNKLKELNCRVKKDCEINFLDTTNEDGERVYFRVMSFIFVMACREIFWDSRVTIEH
                     SLSDGLYCEVHIDRKLKEADVENIKNKMKEIVNNDYVIEKIEVTRNEAISIFENNEMY
                     EKAELLKYKEYDSAKVYKCRNYIDHFYGYMLPSTGYIKSFDIKLYNGGVIILGPSEED
                     KTLPMKFVPQPKLSSVYYEAEEWSRLMGIDKVVSLNKIIENNEYGDIIRTFEALHEKK
                     LSQIADMIKDGNKRVVLIAAPSSSGKTSFAHRLSIHLRVNNLNPISISLDDYFIDRKH
                     TPLDEYGNYDFESIYAIDLEKFNLDLKKLLAGEEIDDIRFNFKEGKREYTGKKIKIDS
                     NQPIILEGIHGLNPILTSSIPDEDKFKIYISALTQINLDDHNRIPTADLRMIRRIVRD
                     YNFRGYSADNTILQWASVRRGEKKNIFPYQEEADAIFNSACVYELAVLKRFAKPLLEE
                     IKEDNPAHIEATRLLKFLQYFVELDDTSDIPGISILREFIGGSKIVD"
     gene            complement(56456..57211)
                     /locus_tag="KOU88_001061"
     CDS             complement(56456..57211)
                     /locus_tag="KOU88_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HBK3210964.1"
                     /translation="MAVGIASLLFNIEEALNICESIKQITHLEIGIDNISECSELCKY
                     KERISKLGLSIGIHLPMELNTCENIEYIRNSWINFIEKIEFELKGFDLRYFNLHLGYV
                     MTNRVRKNRDKYLGNSVDFLDKLNTNSYVCIENTYSKGGDFSNIGNISYDFEYIFKRI
                     KNSKICFCYDTGHCLIDEDAYVKNLKDKIRLIHLSDNDGINDTHVGIGRGILSEEGIK
                     EILTLDAEYLVLEINYEDIEDTISKLNNIVGEG"
     gene            complement(57221..57757)
                     /gene="lepB"
                     /locus_tag="KOU88_001062"
     CDS             complement(57221..57757)
                     /gene="lepB"
                     /locus_tag="KOU88_001062"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK3210965.1"
                     /translation="MNETIKEEIVEWIKIIITALFFAFIITRFIKPTLVNGESMYPTL
                     KSHDYLVANRMTYKLSEPKCGDIMIFKTDLLQENGRKKELVKRVIGVPGDHLKIKDSK
                     VYINGKLLNEVSYIHDNYTEGDIDMVIPKGKVFAMGDNREVSLDSRYKEVGLVDEENI
                     KGKVILRVFPFTDIGIFE"
     gene            complement(57923..58459)
                     /gene="lepB"
                     /locus_tag="KOU88_001063"
     CDS             complement(57923..58459)
                     /gene="lepB"
                     /locus_tag="KOU88_001063"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK3210966.1"
                     /translation="MGEAVKKEVVEWIKVIVIALVLAFAITRFIVPTIVKGESMYPTL
                     VERDYLIVNRIAYKVGEPKYKDIIVFKTDLTEENGKKKDLVKRVIGVPGDHVKIQDSK
                     VYVNDKLLDETSYIHNNRTDGDIDIVVPEGKLFAMGDNREKSLDSRYDEVGLVDEHTI
                     LGKVLVRLYPFSKIGTID"
     gene            complement(58559..59869)
                     /locus_tag="KOU88_001064"
     CDS             complement(58559..59869)
                     /locus_tag="KOU88_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBK3210967.1"
                     /translation="MTELPKEFLEDIEEILKDEYDDFIKSYEESKTTGLRINTLKIDK
                     KKLFDLELFDLNQIPWAEEGFYYDDKIDRPGRNPLHEAGAYYLQEPSAMSVIPKADIK
                     EGEKVLDMCAAPGGKSTYILSKLNDTGLLVSNEINASRIKALGENLERFGARNCIITN
                     TDSNSLRKTFNGYFDKVIIDAPCSGQGMFRKDEVAISDWSYAKVVECQSIQKEIIRDG
                     YKMLKKDGILIYSTCTFSREENEHVINEFISEYPHAELIEMERLWPHKIKGEGHFVAK
                     IKKLEEEECNVKELKIKNLDKEIKDYREFEKKFLKVDFYSNKKNKFYLRGENLYLLPE
                     IYPDTKKLKVLRYGLHLGVLKKNRFEPSHALSHYLKVEDVKNVENFSVQSESILKYLK
                     GDVVNSNDSRGWVLVSVEGIPLGWGKESSGVIKNHYPKGLRKVF"
     gene            complement(59948..60664)
                     /locus_tag="KOU88_001065"
     CDS             complement(59948..60664)
                     /locus_tag="KOU88_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HBK3210968.1"
                     /translation="MKLDLFLLAIIPILIGMFWIRSKDRYCREPLIHLIKFFLIGAFL
                     SVIIILLENLLMKFNVFEGYSELIYVSFVVAGLVEEGVKALILIPALIKEKHFTEKLD
                     GIIYSVFLALGFATIENMVYIFSESRNLALQVGINRAVISIPAHVMFAITMGYYISKY
                     KFEGNKNKRREYLFMAVLIPILLHGVFDFILMIEYRWAIILLIVYVIILWKINLDKLE
                     KYMNHSKKVFFGNLRKKKKK"
     gene            60909..62180
                     /gene="sleC"
                     /locus_tag="KOU88_001066"
     CDS             60909..62180
                     /gene="sleC"
                     /locus_tag="KOU88_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore cortex-lytic protein SleC"
                     /protein_id="HBK3210969.1"
                     /translation="MQDGFLTVSIIDATNNRPIQNAVVNIYSMSNGSQSSSTLYQNLR
                     SNESGQVTGLVLPAPDVDYSLQPSDVRPYSQYIVEAIADGYETVVIEGTQLLATIEAR
                     QGVPMSPRTRSKRSFSRQSELIFDIGEHTLYGTYPPKIPESNLKPLPPPTGFVVLDNP
                     VVPEFIVVHDGLPEDSSAPNYWIPFKEYIKNIASSEIYSTWPEQTIYANVIAIISFTL
                     NRVFTEWYRNKGYNFTITSTTAYDHKFINNRNLFEPINVVVDAIFNTFIKRPPTSRQP
                     LLAQYCDGQKSQCPDQMTQWGSKDLGDQGYDYESILRYFYGDEIVFERAPIVSGVPVS
                     FPGTTLQVGSSGQYVRTIQNQLNAISNSYPAVPKVIEDGIYGTDTENAVKIFQGIFGL
                     PQSGVVDFKTWYEISRVYVATTRIASLNPLI"
     gene            complement(62606..63262)
                     /locus_tag="KOU88_001067"
     CDS             complement(62606..63262)
                     /locus_tag="KOU88_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210970.1"
                     /translation="MKKGDFIWSGVLICIIAVLAIPSSREVFMEATGAHPYIGGFLKF
                     AVLATMGDLLGVRILYKDWKIPVGVFYRAIVWGIIGVVTTYGMSIYSSGVGQAQVDGM
                     LPFEGIAFANALFKSATMNILMSPTVFLFHKVMDCFIDKKYEVGKGIKVKLKDVVNIV
                     DWNAYLGFSVLKTIPFFWIPCHTIVFLFPAEYRVIASAFASIALGLILALANKSKVAV
                     "
     gene            complement(64374..64784)
                     /locus_tag="KOU88_001068"
     CDS             complement(64374..64784)
                     /locus_tag="KOU88_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210971.1"
                     /translation="MKIKKSLISAMMVSAMVLGGTGAVFANGNDSSNIALPKFESLIK
                     SGITDPTELEKYGVEHYTYEEYAKHIQELKDYAKDPNAVKDVSQKDLEETIKKMEQEL
                     EKIKTEGLKIMKPITIENEDGSQISIAYNYAAID"
     gene            complement(65000..66382)
                     /locus_tag="KOU88_001069"
     CDS             complement(65000..66382)
                     /locus_tag="KOU88_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBK3210972.1"
                     /translation="MFIKLLEMSFTSGVLLLIVIFIRACLFKKLPKKVFVLLWLIVLF
                     KLLIPVSLNSGFSIYSIIESTFDVELGNTSTENYTLKKASDSTGKNNSDEFEIMSNIE
                     NIMMLEMLGILSFIVTIMFSILLCFRYFKIINLFKTSIHIKNHEFIKKWMCKNSRFRR
                     FIVCISEFTRTPLTSGILKPRIILPKQMNYANNQTLDFVLTHEMVHINSFDNLLKLFM
                     LVALVVHWFNPLVWVMFFLLNKDIEFSCDEKVMSILGEEYRADYATTLISLAEENNPF
                     SMTICSGFGKTKIEKRIVNIMKFKKSTYVTFLVSTVLVCGTGLVFATENKEINEVESF
                     GLTKNEQSDKIGFSISSKSTDLYSPKVESDILVSKAKSDGETHFSTAKVSVIEFREHE
                     ESSMSKVTNSENSEETYVNKSSNSKDVLYTDSGEVSIERSGYNDNRFVILRKGNLLAV
                     NKEQYRTWIE"
     gene            complement(66393..66752)
                     /locus_tag="KOU88_001070"
     CDS             complement(66393..66752)
                     /locus_tag="KOU88_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3210973.1"
                     /translation="MEIKLFDSELKVMEVLWERGESKAGELVKILKEETGWNRNTTYT
                     VIKKLVSKGAIERIEPNFVCKALISKEEVQKQETETLINKMFGGSSEKFLSAFINKEN
                     LSSDEITKLKQIVEKLK"
     gene            complement(66957..67736)
                     /locus_tag="KOU88_001071"
     CDS             complement(66957..67736)
                     /locus_tag="KOU88_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBK3210974.1"
                     /translation="MVSRQELKRVSKAQLSGNWGICAISMAVYIALIVLISIVGLPFE
                     PLTTIVVAVIAFCVSAGFTCMFLKITKDEKVKIGDIFVSGRIYLRSFGFYLFESIIVY
                     IYSFIITIIGAFLSFGVLLTSGAIEYLSSDNVGIGTIISTGITLVLIILVLMLPVYIL
                     LLYVSQATFLICEDKDNMGVFKSMGASLDMMKGNVLKLFVLNFSFIGWYILSIATLGI
                     GLLWLIPYVGVTNCNFYRQLVKENPDVEDILLDKEKSYTMY"
     gene            complement(68197..68808)
                     /locus_tag="KOU88_001072"
     CDS             complement(68197..68808)
                     /locus_tag="KOU88_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK3210975.1"
                     /translation="MKMVKKLILSTIMALVLVLTIGCSNAEEKVKSNFEANLAALEMY
                     KYDEKGISDALTEAEYKQIQTYNSKDKVSMIAQLTPLYGKENAEKIYETIVKLIQGVE
                     KTVTVESSSKDKITLKVVSKALDTSKVMSEANTLVKSYVTDEKNYDKKEKEVQDDMTK
                     MIIDLYNKKPTKEVTTMITYTKKDGKWQPPSNIQKLCEGIYTI"
     gene            complement(68900..69889)
                     /locus_tag="KOU88_001073"
     CDS             complement(68900..69889)
                     /locus_tag="KOU88_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBK3210976.1"
                     /translation="MLLLKKDDIKKVFTMRDAIEADKEAFRIYCEGKSVNPLRTNISV
                     PSQDASMLFMPGYVEELGCGGIKIVSVFPKNAQKGKPVIPATVLLLDGETGEVSAVLD
                     GTYVTQIRTGAASGAAIDVLAKKDSKIGALIGLGGQGEPQLEAMIEARNLDEVRVFSR
                     NKESREKFAEEMNLKLSKYNTKIVAVESSDEAIDNADVIVLATPSKQPVLNGNLVKKG
                     ALISAVGSYMPDMQELCPNCLTRASKIFFESTDAVLSESGDILIPLKEGKISKDDFSG
                     DLGNVINGTIPGREDDDEIIVFKTVGIGVQDVVTAKRIYDKAKENGIGIDWKW"
     gene            complement(69956..70819)
                     /locus_tag="KOU88_001074"
     CDS             complement(69956..70819)
                     /locus_tag="KOU88_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HBK3210977.1"
                     /translation="MKFFKVDTKAKVLRYVFVLTLTIMAVLAIKHDYKYNNLRKDASI
                     NLNSNKEAVTVMSNQSLPKGNTNSKQTLSVSTIGSKTIVKNDEYLESTINMPVITNSN
                     KIVERSTNDKIKNDIFEFYNKSYKEAKQYLKDNPDEKNKFVANVDFELKKNTDSALSI
                     KVRYYTYSGGAHGFYQDIAYNVDMRTGKFLELMDLFKDNTKYKEVIDEEIKRQIAELE
                     KKDEENIGIYNFKGIKENQNFYLQDENLVVYFDLYDITPYAAGIPEFSINKALISSML
                     KPEYVDLFDLK"
     gene            complement(70925..71521)
                     /locus_tag="KOU88_001075"
     CDS             complement(70925..71521)
                     /locus_tag="KOU88_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheB"
                     /protein_id="HBK3210978.1"
                     /translation="MERFNNMVIAIGASVGGTEAILEIIKDLPKSTPGIVVVQHMPAI
                     FTYMYAQRLDKQCIMNVREAKNNDRVEQGNVLIAPGGYQMKLCTDKQGYYVTCEKGER
                     ISGHCPSVDVLFDSVAEVAGKNSIGIILTGMGYDGASGLLKMKENGSFTIGQDENSCI
                     VYGMPMVAFDRGSVMLQLPLGEISNCLIRHINILKQKD"
     gene            complement(71561..72364)
                     /locus_tag="KOU88_001076"
     CDS             complement(71561..72364)
                     /locus_tag="KOU88_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBK3210979.1"
                     /translation="MIKLTDEEFIVLVNHVKKEYGIDLSKKRALIEGRLYNTMIEKKL
                     SSFSQYMNLLFKDRTGNEAINLINRLSTNHTFFMREPQHFEFIQNSILPFWEENNKIR
                     NINIWSAGCSSGEEAYSIAMTLDDYFGYNKELWNIKIIATDISTNSLEKAKRGIYIES
                     NVNNVPELWKKKYFIDNKDGTFKICDKIRKSVIFKPFNLMNDFSYQHFDLIFCRNVMI
                     YFDLKTREELINKFYNATKKDSFLFVGHAEVINRSSTKYKYVKPAIYKR"
     gene            complement(72400..72840)
                     /locus_tag="KOU88_001077"
     CDS             complement(72400..72840)
                     /locus_tag="KOU88_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBK3210980.1"
                     /translation="MAKDEIIKQVLTFYVNDVIYGIELENVIETIRFQSITYVPCLPT
                     YISGVINLRGRIIPVINMHIKYNLPKADYNERTCIIITKVDEYQVGIIVDKVVDVIHI
                     ENLNLLETTNSNNTNINKDIKEIAKVEDNSILILDIRKFLINSI"
     gene            complement(72853..74955)
                     /locus_tag="KOU88_001078"
     CDS             complement(72853..74955)
                     /locus_tag="KOU88_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBK3210981.1"
                     /translation="MRQMLDMFIFETSLLLEQLDEIMIQIEKEKVFTHNNINETFRIM
                     HTIKGSASMMGLDNISALAHSVEDLFYAIREGKIEVLDNDLLFDLVFQSLDFIRRDID
                     ELQSRGCISSDYSNFIEGIEEYVSTLELSSSMKSKDNANLESKDEKEVIDSNFEYKED
                     SDVVKIIFEQGCMMENVRAFMLVFELRDYCEFIDFYPKDVETNAESTEYIKSYGFYIQ
                     FVAKEDKAIVYKTIEDNLYVKEYINISKKEIEMKSTSNNDAVENKLKDNNKVSKSYQN
                     NYTEDEIQEDVLNEKTDMEKDSLSEENEHLPISKQSIMSVNLEKLDLLQNIVGEIVIM
                     ESMVVNSVNSTGVDIDNFNKATRQLHKLTDELQDIVMSMRMIQIAGVFQKMHRIVRDM
                     NKKLDKNVELITIGAETEVDKSVIDNLAEPFMHLIRNAMDHAIEPIEERIAKGKEEVG
                     KIVLSAENLGGEAVISISDDGRGIMRDKILAKAKEQGLLKHQSNEYTDDEVNSLIMTP
                     GFSTKESITEFSGRGVGMDIVRKSIEKVGGSIEVKSKQDEGTTFTIKIPLTLSIVEGM
                     KFKVGDSLFTLPISSIRRTFKLTDLNQIITEGNKTELITIYGACIPIIRLHKIYNIQT
                     KVTNLMNGNMIIIENEHKAVCIFVDEIIGNQQVVVKPFPVYFNRFNIKNKGLSGCTIL
                     GDGSISLIIDADSIIEIY"
     gene            complement(75216..76919)
                     /locus_tag="KOU88_001079"
     CDS             complement(75216..76919)
                     /locus_tag="KOU88_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing protein"
                     /protein_id="HBK3210982.1"
                     /translation="MKREVKLSKLAIVLLIIIVLAVLAGIFSSISSYKAFEKVEKSIN
                     DMNNLRTQSQYIKDTTREISDVLRRYVFTGEKKNKDIYEKELYGKTRESALNKLEKIG
                     LTKSESNKILEAKEISDSLVPTEQSAIKAVESNDKSKAQSIIFGSDYINSQEKMDSLI
                     NEFQEDIVTRSNSKIVEVKKELQSLILRTIFILSLLIILTIIEYTVIKLKIVIPINKV
                     EKHFSRIASGDLRTSIDVEESKSEIGLLVSSVKKMQSMLLNYIDLIDSTLTSIAKGDL
                     RVEIDQEFIGDFKSIKISLESIINSFNGDFSEINLSAEQVASASEQVAAGAQALSQGA
                     TEQASSVEELASTINEISDGIKKCADSASLACEVSDQSASQVGFGSRCMDDMMTSMGE
                     ISEKSSEISKIIKTIDEIAFQTNILALNAAVEAARAGQYGRGFAVVADEVRSLAGKSA
                     KAAQNTAILIEEAIKTVENGVRIAKETANALDLVVNGVEKTTNYINGISSAVHSQEVA
                     ITQILSGIEQISIVVQMNSATAEESAAASEEMSAQAQILKELVEKFHLKESEVRESSW
                     V"
     gene            complement(76945..77904)
                     /locus_tag="KOU88_001080"
     CDS             complement(76945..77904)
                     /locus_tag="KOU88_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBK3210983.1"
                     /translation="MKNKQQGTILVVDDSVLMCDLIDKTLTKDNFKVKKAFNAIEAKE
                     FIEEFIPDIILLDIILPDNSGFEFCKEVKSNARTADIPIIFITSKNTDTDIVKGFGVG
                     AIDYMVKPFSMTELKARVIAHLEVKKSQDKLKKINNELESSLEKLNRLVVRDYLTGLY
                     NRRHIINQLMEQRRINKYSETSISLILGDIDDFKVINDTYGHEAGDFVLTVISSIIKK
                     NCRQIDTVSRWGGEEFLIMLTNTPIEGAKILSERIRKEIKEFDFNYKEHKIKCTITLG
                     VVEVNSNISLEENISLADKAMYEGKNLGKDCSVVSTMKGLKKI"
     gene            complement(78040..78558)
                     /locus_tag="KOU88_001081"
     CDS             complement(78040..78558)
                     /locus_tag="KOU88_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-binding chemotaxis protein CheW"
                     /protein_id="HBK3210984.1"
                     /translation="MRFPDDPYLDYGLIDEGIKYLKFKVDEQDFGVELEKVIEITGNQ
                     EIIFIPELPTYSKGIINLRGKIIPIIDMRLRLKKDELMTTNCMYIVVTEIKDLVVGFV
                     VDRVDDIVSLEKSKISPPPRVTIEYSDYFVSGVGELEGKIITLLDLEKLLTDKDEVLI
                     DELINGFDCTIM"
     gene            complement(78601..79086)
                     /locus_tag="KOU88_001082"
     CDS             complement(78601..79086)
                     /locus_tag="KOU88_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheD"
                     /protein_id="HBK3210985.1"
                     /translation="MNREIVVNIADMKIAYRPNVLVTYALGSCVGVCLIDKVAGIGGM
                     LHVMLPYSKDAINIENKCKFADTGINELIKSMENIGANRIYIKAKIAGGAQMFLGSSN
                     SVIASIGHRNVEAVKKTLLGLNIPILAEDTGMNYGRTIRFYTETGELLVDSINKGKKK
                     L"
     gene            complement(79083..79700)
                     /locus_tag="KOU88_001083"
     CDS             complement(79083..79700)
                     /locus_tag="KOU88_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheC"
                     /protein_id="HBK3210986.1"
                     /translation="MINYLELDDVHIDALREIGNIGSGNAITALASMINSNVEVLIPM
                     VKILEYNEATNLLGGPENKVVCILLDMKGDINGMFMFLLDESITQLMLSSLFNKEEAF
                     LDEIEAIEISAIKEIGNIMASSYVNAIASMLNMTISVSISDICIDMVGAVLNVPMIRF
                     SDVGDKVLFIENKFKMSDNYFTSHILMIPEMSSLREILVRLGLEV"
     gene            complement(79765..80127)
                     /locus_tag="KOU88_001084"
     CDS             complement(79765..80127)
                     /locus_tag="KOU88_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK3210987.1"
                     /translation="MENKILIVDDAIFMRMIIKEALSKSGYNNLIEANDGEEACNIFK
                     YEKPDLMLLDITMPKKDGLEVLREIKKLDSSAKVVMCSAIGQENMIVEAIKLGALDFI
                     VKPFKTETLVKVVDNALK"
     gene            complement(80871..81368)
                     /locus_tag="KOU88_001085"
     CDS             complement(80871..81368)
                     /locus_tag="KOU88_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBK3210988.1"
                     /translation="MNYEIVEINEKIVIGISKETTNKDGQAVNDIGELWKKFMGKGIY
                     NAIKGKKNDKTIGLYTDYQGDFTSPYSFVACCEVNSNSDKEKNLEELNTNNTVGESII
                     SKVIPAGKYAKFVIVGGQKEVGDFWFKFWQMDFDRTYISDFEEYQCNTFDTKKQEVHI
                     YIGIK"
     gene            complement(81543..82454)
                     /locus_tag="KOU88_001086"
     CDS             complement(81543..82454)
                     /locus_tag="KOU88_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBK3210989.1"
                     /translation="MKINRLTEIIVILLNKKLVTAKELADRFEVSTRTIYRDIETLSM
                     SGVPVYMTKGKGGGISLIEEYSIDKAILSKKDKESLIVALKTLQATKYPEINSVVNKI
                     GSIFGEQNFSNWIEIDFTEWGSNFNEDDKFTKIKEAILRRNTINFNYVNSLSSQTNRT
                     VEPLKLMYKSKTWYLYGFCKLKDDFRIFRISRIRNLSIKDEVFSRKIIEEVCLNDSKV
                     IKENTITLKLRFKEKMLFRVFDDFNKDLITKNEDDTYDVITEFPIGEWIYGYILSFGD
                     NVEVLEPKDVRDNVITRLRELSKIYSL"
     gene            83424..84275
                     /locus_tag="KOU88_001087"
     CDS             83424..84275
                     /locus_tag="KOU88_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBK3210990.1"
                     /translation="MEINKKHFIQVFLTCLILVVICEFIGQRTIAIGKASIVLFPMLY
                     AVIIGLIITPDLLGKKIKALKKVVGEKEINIAGEVVGIALVMLGIKYGTTVGPNIDKI
                     IQAGPAFIAQEFGHILAPIVALPLALMFGMKREAVGATASISREPSLGVISEKYGINS
                     PEGSGVLGTYLMGTVLGTIYFSVLGSISIYSGLHPYALGMACGVGSGSMMTAAAGSLS
                     TMVPPEMADTILAYAATSNMMSSITGIIFLVFVSLPFTNFMYKILEPKFSRNKKTKEI
                     KSTEGEC"
     gene            84279..84749
                     /locus_tag="KOU88_001088"
     CDS             84279..84749
                     /locus_tag="KOU88_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210991.1"
                     /translation="MFANLNLKKSSYQLLVMSVIGVIILIGQRISVGTSIVTALPGMV
                     MLILAAMAAMIIKDLFPKSIFPAFGFATIIGLLLSMPYSPTSEVFLTNTNNINFMAIT
                     TPLLAFAGISVGNKIEALKEMSWKIVIISLIVFTTIFFACASIAHIVLSIQGKI"
     gene            84762..86072
                     /locus_tag="KOU88_001089"
     CDS             84762..86072
                     /locus_tag="KOU88_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3210992.1"
                     /translation="MNKEQLKSLVIKTIDENREKILKIGQGIYKNPEYGYKEFKTTEA
                     VSNFFEQELNLSVEKNIAVTGCKADANSSKKGPHISILGELDGISCKEHKDANEIGAS
                     HTCGHNIQIAGMLGAAVGLVKSGVLEHLDGKVSFMATPAEEFIELEYREQLKKEGKIT
                     YFGGKQELIKRGYFDDIDISMMFHASDLGEDKALVGPESNGFVGKKVKFIGKESHAGS
                     APHDGINALNAAMLAINNVNALRETFKESERVRFHPIITKGGDIVNVVPADVHMESYV
                     RARTINGMIDANERINKALMAGGMAVGADVEITEIPGYLPILRYKSLDNLFKNNLEDL
                     GLKGKVIDGGDFTGSFDFGDVSHIMPTLHPMIGGVKGALHTRDFEIVDEDLAYIIPAK
                     AMALTVVDLLFDNAKDAKDILDTFTPVMTKEEYLTFLEKHDKTL"
     gene            86284..87030
                     /locus_tag="KOU88_001090"
     CDS             86284..87030
                     /locus_tag="KOU88_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3210993.1"
                     /translation="MFNAGNRIINTWLYPIQDGFVLIDTGYENGFKHFKKRISKFNIK
                     IKDIRYIFLTHAHDDHVGFLNQILDESPNTKIVMHDKALEILYKGQNSFIGGCTSRTA
                     FLFCQIMKLFGKGEHSFSPLKQEFEKRCILVSDKNRKEIEKELNGKIIDTPGHTDDSI
                     SLLIDEGVLFCGDSAMNGFPSTHKITIFAESKLEFIQSWKTIINTKPKMIYPGHGKPF
                     EYSKLEQNLIYVNKINLYPLHNSKDIHRFL"
     gene            87392..88933
                     /locus_tag="KOU88_001091"
     CDS             87392..88933
                     /locus_tag="KOU88_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBK3210994.1"
                     /translation="MNDNVVKKKNFFDRTLNRIETVGNKLPDPVTIFLGLCVLLLILS
                     SLVGSMGISVVHPGTGETITAVNLLTVEQLQILLGNIVSNFQGFAPLGLVLVTMIGAG
                     VCDKTGLMTATIKASVSKIPETRVTLVVMTIGMLANIASDAGTILFPPLAALVYLGVG
                     RHPLIGLFSGYAAVCLGFAANIMISVNDILAASFTVPAAQMIDSGFQANATMNLFFMI
                     ASTFVLILLATWVTEKIVAPRFGKYEGNAELDVDGSLSDVEKKGLKKASISILIYVAI
                     IVALSVIGKKPFLADPETGDLLSNNAPLMKGMVPIIALAFFIPGVVYGKTIGKIKKDK
                     DVVSIMASAMSDMGGYIILAFAASQFLQLFTNSNLGLILAVKGGEFLKSAGINGPLLL
                     IGFIILSCFINLFIGSASAKWAILAPIFVPMFMMVGYNPALTQMAYRIGDCITNPLSP
                     LFPYFPIILAFTRKYDKDAGMGTVIANMIPYSISFLIVWTILLILFMVFNIPLGPGIL
                     PSYSM"
     gene            88968..90074
                     /locus_tag="KOU88_001092"
     CDS             88968..90074
                     /locus_tag="KOU88_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBK3210995.1"
                     /translation="MLDKNRLINNFMDMVRIDSPSNQELEMSKWLVNYLKERNIDAII
                     DDAGKKYGGNTGNVIAYIKGEEGSRPLCLCAHMDQVQPCLGVKPILDGNVVRSDGTTT
                     LGADDKAGIAAILEALEHVITEKIPHRDIYLCFTICEEAGMHGVKNFNPDNLPCKDMV
                     ILDSGGAIGSIAYKAPAQQSIKISFHGKKAHAGIEPEKGLNAILVASHAISNMHIGRI
                     DSLTTSNIGKIEGGGATNIVTDKVTLTAEIRSHIPETLEYELNHMEKCCKDAASKFNT
                     TYTFEHNMSYPSFELSRDSHVFKLSEEAIRQVGVVPNPMVIGGGSDANILANLGYNCA
                     ILSLGMYDVHTVNEYVNIDELYDTAKIVYHMIKL"
     gene            complement(90284..91570)
                     /locus_tag="KOU88_001093"
     CDS             complement(90284..91570)
                     /locus_tag="KOU88_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK3210996.1"
                     /translation="MIVGIIGPSDSGFKIKDDLKQIDSDLKTKIYVREKVVDTIEVIS
                     KCEDECDAIIFTGCAVYEFIKSKYEISKPHSFVPRSGTSIMKAFWAIKSANIKLDKFS
                     IDVVDRYVVEDALKEFDIKATSVFCNPFSLEVGESELVEWHIKLFEENKTDIMLTGFG
                     AVYNELKERGYPVFRLQATIQLIKESYDKVKSEYALSKARFSQIAVEILSLIDYKEKI
                     DNYYSDMIKKSDMDKLVVNYVRSIQGSLFLLGRNDYVVFVHKGVADNEYNYDKLFNLK
                     REIKDMGFSLSIGIGTGVTAYQAENNAHKALRHSIDSKEIGIYLVDEDENIRGPLASE
                     NELNYSLMLSDEKVIEISKKTGMSCESVAKIIAINENRKSKIYDSKELAEYLNVSERS
                     ARRILNKIVNAGLGRICAKETSIGGGRPKNITEILF"
     gene            complement(91693..94791)
                     /locus_tag="KOU88_001094"
     CDS             complement(91693..94791)
                     /locus_tag="KOU88_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBK3210997.1"
                     /translation="MDVINLIDELDEIVYVSSLDTYELLYINEIGKKAMGLNDISHLK
                     CYKALQGKDSPCEFCTNSILKEDEYYIWENTNTRTNRHFILKDKLIKWEGKHARLEIA
                     LDITEKEDISKSIAEKLEIKELLVGCIKHLITESNFSDAVNLVLTNIGKFHKADRAYV
                     FEVSEDRTKVTNTYEWCNEGVDEQKQALTNLDINELKNWFLLFEQKGFVIIDDIENIK
                     EEQPIEYEILKPQKIESLMTSSLKQDDKVVGFIGVDNPHKAVGDTSLLTSLSYFLLTE
                     MKKRKVENKLNYMSYYDFLTGAYNRNKYIKYIDNFQKGKVKSIGVVFVDINGLKDIND
                     NFGHANGDSAIVSACVIIKKYFHSYNVYRIGGDEFVVLCEDISKQLFEELVSWLSEEF
                     KDEMIYSVAVGSIWSDDNIDIHKLIKVADERMYQDKKRYYNKNKLRNNEMKVISDLAD
                     STNNILFKHKELVDKVYFDDLMIKGYSKAYEKLAYNTYDIILSICIDTNLITPIYQSE
                     SNIFSFPIKENLEKTFSYIKKHLIHPDDIILFNDNHLLKSLDSLNNSKQDDLELNFEY
                     RRLGIDKKYYWALIYMLKISSKNKLGEKQTHILVAIKNIDYLMQLHKNQKDTLTGLYN
                     YESFCEQISLMLKRYPDKRYAIIMMDIDKFKVINDIYGVRGGDKALIYVAELIQKNIG
                     SNGICCRMYADVFCIFYESYSDRDIHKVIYKIKNSLNRKKFEYMLVPCFGVYRILDNH
                     IPITNACEMAGYAHKKVKKQSINNYIFYDDTIRNDALEEKQMEREMEYALENGQFHVY
                     LQPKYNLNANKIVGAEALVRWVHPEKGIIPPIKFISLFEKNGFIIRLDMYVWEQVCSL
                     IRKWIDLGEEPVPISVNVSRLHLHNPHFKEIVLSLINKYSIPKSFLELELTESLFIKN
                     IKLFTKIIADLRMDGIVLNMDDFGSAYSSLNMLKNINIDTLKIDCGFFNEEGITDREK
                     IVLKHTIAMAKDLDMDVVAEGVETKEQAEFLVSLDCVVIQGYYYCKPIPSADFEKLLY
                     QK"
     gene            95516..95674
                     /locus_tag="KOU88_001095"
     CDS             95516..95674
                     /locus_tag="KOU88_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3210998.1"
                     /translation="MKIFSFLLFVIGICLCIAGFIGHYPVFVGTTLSFLAIAMIAVRQ
                     VKTKKKMK"
     gene            complement(95961..96665)
                     /locus_tag="KOU88_001096"
     CDS             complement(95961..96665)
                     /locus_tag="KOU88_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3210999.1"
                     /translation="MEIKPLVLIVEDDKPICKFIKVSLETQNYRCVETDNGGTAISLI
                     HSLDPDLIILDLGLPDIDGIEVIGRVRACAKTNKIIVVSAREHERDKVEALDGGADDY
                     LTKPFSVTELLARVRVALRNKAQQDNINNDAPKSFEVKNLKIDYENHIVSINGEEIHL
                     TPIEYKIIELMSKYSGRVLTHKFIIDKVWGNYYESENQSLRVFMASIRRKIEKNPAQP
                     EYILTEVGVGYRMADE"
     gene            complement(96656..98263)
                     /locus_tag="KOU88_001097"
     CDS             complement(96656..98263)
                     /locus_tag="KOU88_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4118 domain-containing protein"
                     /protein_id="HBK3211000.1"
                     /translation="MKKERLQHEDLKEYDYDEDGYLSKKIIIKDFIKTILVMTIATGI
                     SVVFEKVGFNESNIILVYILGVLFATSITYGYFFGILSSVIGVLSFNFFFTHPLYTFL
                     AYRKDYPMTFCIMLMAAIITSTLTSRIKREVRLSHKREKMIRLLYENNKTLLKAKNKN
                     QIIEFCGSNLVNILNRTVIVTIADENNNLGKPSIYICNNDGSENIFHSVLEKEAIKEA
                     FRTGNPVGIGTKYCKNSSAYYFPIKGQESNVLGVIGVACFKIDIITENEKILLEAVST
                     QVALAIDRENLFEKNKKANLEAERERLRGNLLRSISHDLRTPLTSILGSSSTILENDD
                     VIDKETRVELLKNIYEDTSWLTHSVENILSMTRIDEGKLDIEKRPEVVDEIIAESILR
                     VKKFANSRDIKTNIPDEIIIVHVDVLLIEQVLVNLIDNAIRHTPKNSKIELTVKKESN
                     QVLFEVADNGKGIPNEDIGNIFNRFYTKNKSRNLERRGIGLGLEICKSIVEAHGGEIV
                     AFNNPSGGATFRFSIPMYDEEGKDKWK"
     gene            complement(98517..99695)
                     /locus_tag="KOU88_001098"
     CDS             complement(98517..99695)
                     /locus_tag="KOU88_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211001.1"
                     /translation="MEKLSDKRRVKAVSMETFVFIVLLAVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLDTVFLIMAMAVLAGALSALLSEFGVISLVNKIFKGLMRPIWGLPGASIA
                     GVVATYLSDNPAIIPFAKDKTFTQYFKKYQVPALCNLGTAFGMGLIVTTFMIAQGKEY
                     VLPAIIGNVAAIIGSIISVRIMLTFTKKYYNYDPKNDTEKQINDKGAKLEEFREIRDG
                     NVFQRTLDAILEGGKLGVEMGMAIIPGVLVVCTLVMLLTFGPSTDPATGQAVYTGAAY
                     EGIKLLPAIGDKISFIIEPLFGFTSPEAIAFPVTALGAVGAAISLVPEFIKSGAITPN
                     DIAVFTAMGMCWSGYLSTHIGMMDALDARPLAGKAILSHTIGGLCAGICAHFIFMLVG
                     "
     gene            complement(99921..100415)
                     /locus_tag="KOU88_001099"
     CDS             complement(99921..100415)
                     /locus_tag="KOU88_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBK3211002.1"
                     /translation="MHLFIEVIAAFFTALSFGVLFNMKGKNLILAGIGGSIAWFSYKF
                     LLNMGVTENLCFFIATVCFAIYCELCARIYMTPATTLSVCCLIILVPGYGIYNTMYSV
                     LTNNYIKAVEYGVSTLSCASSIALGLVFITTVFRKVNLYGVLTKIKENEKYKKSINKI
                     KQQK"
     gene            complement(100416..101177)
                     /locus_tag="KOU88_001100"
     CDS             complement(100416..101177)
                     /locus_tag="KOU88_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBK3211003.1"
                     /translation="MDIDRILNFSSNAGKAMLQSGGETYRVEETIARICQSFGIDHVD
                     VFATPTAVMASVFVDGKLHSAIKRISSRRVDLNLVHEVNSLSRAISINNLDIELCEKI
                     LDEISEDNYYSDLITIFFAGIAAATFSILFGGNVEEFIAAFTVGILTKFVIMYLSKSS
                     LNDFFVNAIGAVIIASCSILILKLGFIKTLDHLIAGAIMLLVPGLALTNALRDLLDGQ
                     LISGLAKLAEVFFVGVSIAVGMFLVLGLYFKLGGI"
     gene            101899..104733
                     /locus_tag="KOU88_001101"
     CDS             101899..104733
                     /locus_tag="KOU88_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3211004.1"
                     /translation="MLRKDKVLLSLHKLCENMTLKDLQSDKTGFTTIEIANHSSLDRS
                     NTSKELNNLYNEKKVLKISGKPILFLHASIIENLIGRTLNSDEFSINNCNELLKSSKN
                     DSEDIFSTLLGHDSSLKLPIEKAKSAILYPPKGLNTLLIGPTGVGKSTFSETMYKYAV
                     ESKIFSSESKFVVFNCAEYAENANLLLSNLFGYVKGSFTGANKDKFGIVAQADGGILF
                     LDEIHRLPPEGQEMLFLLMDKGIYRRLGESDIVHKANVFIVCATTEDIHSSLLGTFLR
                     RIPVTINLPALQDRSLKERLSLIKYFFIIESKYTNATIKVHKDVIKSLLLYDCFGNIG
                     QLKSDIQLMSARAFLNYKTGLKDNIEIDLSLVPDYIYIGLLKLNENRSNLNKLSELDY
                     MLFYEFNGNNLEVEYTKELSKYNIDTSNNGFKYSTEIPYLENDIRSMFINYMEKYSTK
                     LLSISSVTHSDYTSNEIFKVINPKIYYAVEHSLKEAEKISRNKYTKQTYIALSMHISA
                     LIENINQDTYNPKYNLYNDKIFLDKDLNIAKIVLSIIENDLQTSLPKDEVKFISMFLN
                     SMYLEPNNQSESIGVIILAHGNSTASSMCDVANSLLGTNHCNAIDMPLDVKVSTILDK
                     TIELVKECDEGKGVLLLTDMGSLIAFGELISEKTKIKTRSIEMVSTPIVLEAVRKSTL
                     PEMTLDELANSLSSLNPYIGRAAIDSTEINYPEKSREYVIITTCITGYGSAMKVADFI
                     NSSLKNISKYNINLVPHNIESFKMYKNKFSNTKILAVVGSVDFNVANTPFIHIEELLN
                     GYGLDMLNKIIEGTFNANSITNIKETNLSYNSLIINFMTQNLELLDSVKLFNYVNSSL
                     FTIIELIDENLKSKFKLGYILHCSFMIERCFKNTTFPYNNITELISKNHELYSLIREA
                     FKPTEAYFNILIPDEEIAYIIDMINEYLNK"
     gene            104776..106020
                     /locus_tag="KOU88_001102"
     CDS             104776..106020
                     /locus_tag="KOU88_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBK3211005.1"
                     /translation="MEDEILKGKIKQLTILALIFIFITPVFAFADTPPVPNSSRAALL
                     IDQETKRILFEKNIDEKMPLASLSKMMTFLLAIEAVDKNQVKETDMVKIDKSTASVGG
                     STCKLKDGDEISLGELMQGLMLVSGNDAAIAIAKHIGKTEKNFVNMMNKKAEEIGMID
                     TYYFNPNGLPIYTDPEHKEPPIENMSTAHDIVTLGKYMYDHYENQVTRITTMQVYNDT
                     KKDFTHYNTNPLLVSVPGVDGIKTGYTDNAGYCLAFSMMVPKDAKNERNHRLIGVVLG
                     DGNKKNRISSSATLLKYGKDNFHSKKIAHKGDIIETPCVDGIDDFKITVKVDKDLYGV
                     VSDNENINPKVVFKNMNYPIHKGDIVGVAKYYNDSGKFVGSVDVKSESNIGCIPLKDK
                     IKIKVAKINKKLEIKNSVCFKA"
     gene            complement(106435..108177)
                     /locus_tag="KOU88_001103"
     CDS             complement(106435..108177)
                     /locus_tag="KOU88_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211006.1"
                     /translation="MKKTINNNLFRILNIIVYKNKTKLIVSFIMVFIIAGVNIVIPQL
                     IRCIIDDGIGNKNIFLLINLILIYIFIRILSATFDVILSYLYTSIKNKVTINLKVKLL
                     NHISKLSGRYYSSKKTGNILSIMESDIFMIENFGAEIIFDIIVNVFTAIISLIFLINL
                     QFDLFLVVLFLQLILTFSQNKMTKLISKKISEIRSDSGSLSNLIQEYVSNIMDIVILN
                     SKKNFFNKYLKRERDLIKKDLNLNIIMSSNIAISQILTGLITILIYGIGGYKIINNKM
                     TMGELIAFQQYTGMLIGPCIAIVRANTRIAQSKVSINRVFSVIDEKIDIKVDNNGYRI
                     DNSEIKKIDFKNVSFRYGEDLNLVLNDINLQFEKGEVTGIVGGSGCGKSTITNLIYRL
                     WDINEGDILIDGVNIKDINLKSLRNNIDIVTQDQFVFDDTIKNNIVLNNKISDKELDE
                     ILEVTCLDDFIKNLDKGLDEVVGEKGVKISGGQKQRISIARALVSNKKVLILDEATSA
                     LDNISQKEILNNLKEYIQDKIVIIIAHRLSTIKSADNIYVLDKGRVIESGNDAELLHK
                     DGLYNKLVETADFA"
     gene            complement(108161..108835)
                     /locus_tag="KOU88_001104"
     CDS             complement(108161..108835)
                     /locus_tag="KOU88_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211007.1"
                     /translation="MKILKVKDLKKIYGKYENEVRALDGIDLDIEPHKFTAIVGASGS
                     GKSTLLHCVAGLDKPTLGNVYLDDVDLYTLNDDKLSEIRRQEFGFIFQSYNLIPVINV
                     YDNIVLPVLLDGKKEDKEYVMRLINKLGIEKQIKKYPNELSGGQQQRVAIARALANRP
                     SVIFADEPTGNLDSKTTNEVMNMLEWCVKEYKQTLVMITHNDNIAKTADRIITIKDGK
                     IDEKNY"
     gene            complement(108872..109861)
                     /locus_tag="KOU88_001105"
     CDS             complement(108872..109861)
                     /locus_tag="KOU88_001105"
                     /inference="COORDINATES: protein motif:HMM:NF012311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBK3211008.1"
                     /translation="MTKVRIAVLDTGLDVNDDDINGNYVYDSNFQLKDLGGKEINDIN
                     GHGTFVSKTILNISKNTQIYPINIFNDSGKTSSLNLLSTLSKLTMSDIQIINISAASI
                     NSMYEKELEKVCNILNSQGRFIICSKHNKYEDKESIPTIFESVIGVVGNENIYKNNQY
                     IYEPENKIQMYANSKDNFIKFKDKVTHFGKNSKACAVATGIVANILKNNPYIKFNELE
                     EILIQKSKSKEDLKIENLNTPSYKSNLIRLDIARKIINVINRNFSKIKIDFEFVSEYS
                     LFNNFTCIGNYNAYNFLTILNKEFNISIDYKEVYLYQLENLDMAVDLIYENLI"
     gene            complement(109909..111153)
                     /locus_tag="KOU88_001106"
     CDS             complement(109909..111153)
                     /locus_tag="KOU88_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3211009.1"
                     /translation="MNSSNKYFLDCICEKIINNNQVILSNKVNGRWVKIPIECYEVLK
                     YSVDNALQLGNLYDVFQENEDKKYYERVIDKLEHIGLLSDSILSEFRLERINKISFSP
                     TNRCNLSCDYCCVDSKIDNNDYLDTSQVRKVIDNIVKLNPRILTITGGEPLMRNDFLE
                     LLDYIKEKFKGKIILSTNATLIKEKQIDDIINGLYAIEISLDGYDELSCSEVRGKGVF
                     CKVLNVIRLIKLKKFENVGLSMVVGKNNEKDIEKFNKLNEDLGTTPIIRNFMNIGRGN
                     ENYSKYLNDKLDIDYICKDDYVDESSLCSNMCKAGVNQISIDHKGDVYPCPNLEYKDL
                     KIFNILEFNENILERILNREMDIFNIFDKLKPVNIESCKECKVNLFCTTCPSKIYTLK
                     NNKKMFDANCKKMKNILEPILW"
BASE COUNT        36927 a        19272 c        14797 g        40209 t
ORIGIN      
        1 tatatattaa acttttatgc atcactttta tacattagtt cttatatatt aaacttctat
       61 gcatcacttt tatacattaa ttcttatata ttaaacttct atgcatcact tttatacatt
      121 aattcttata tattaaattt ctacacatca aatttatata catttaaatc acatgattaa
      181 ctgctttctt cacatttcta agtggaatag caattttaac tacaaatttt ttatcatcat
      241 attcaattac aacattacca ccatacttat ttacagagtt ttttacactt tttattccaa
      301 gtccatgaag agaacctttt ttgtctgtca aaatatctcc atttttagta ataatcttat
      361 ttatcttagt attttcaact cttattaaat aaaaattttg cataacatca cctttaacac
      421 aaataactct atttccacta tcaattttat tacatgcctc aattgcattg tctaaaatat
      481 ttgaaaatat atgacatata tccactaatt caacagcttc acaacaacta aaatttattc
      541 ctatttttag ttctatatca ttcttatcac aaacctcttt cttttcactt aatatagcat
      601 ctaatataaa attaccagta ttaaataaca agtcattact ctgaatttct acctgcaaat
      661 tatttaaata agaagtaaca tcaatacctt ttttaatcat agcatttata cacaatatgt
      721 gatttttcat atcatgactt agtaatctag tttttaaata tttcttttct atatcttcat
      781 aatactcatt ttcatacttc aaagtatttt taatcatatt gttttctaca actaaagtat
      841 tatattgctg taatttttta gcaattaaaa ctaaagtgat acttgatata agcaatacaa
      901 cagaaatcat aacgaattgg aaattatgta ttaagctacc agaccctgga ttaaatatgt
      961 attcaaaaat tacaaaaaaa gatgctatat tagcgactat aggaataact atataaaata
     1021 atgtcctttt atttatttct atattaagtt ttatctttaa ggctctatat aaaagcaaag
     1081 acacaatcaa aagtatcttt cccaatatta tagactcaat tctgtatata tctcccgtcc
     1141 ccatactact catgtcattt atagaattaa gccaaactgt taaagatata ctcaaagcat
     1201 ctgtggcgat tagtaacatc caataaatta aggatattaa tacagacttt ataaacccca
     1261 catcatatga gattttataa aatgcaatag taattatcat agatataatt actcttatat
     1321 ttggaggtac atcaaaaaaa tatattatgt cagcaaaaac aataatacct accatacaaa
     1381 agtttatttt tttgttagaa atccttttct cacttgtata atctagcatt ttcttacaaa
     1441 gaaaccattc tatcataaag gatatcgcaa tgaaaatatt ccaaaataag cttgacttta
     1501 tcataatact ttctcctaac gtattactaa attatttttt tatattttat gtataattta
     1561 attatatacg actctacaca tgtagtaaat agattgtcaa aattattcca aataagtcca
     1621 tatttctttt cttttttaat tatatcacta aatttgctaa attgaattaa actttttatt
     1681 gcttttttta ataataacta tataaattta tctataacta ggtataaaat atattattta
     1741 taaagttttt acattatttc ttcctcaaaa acgcaataaa aatctgatta tccgctaaaa
     1801 cacagtatct atcagcattt tcaaggaaac aaacaaatca atttactact tatttactac
     1861 taacgaatga gccttgatac gcaagttttc ctagatatgc aaagatatgg tacagcacat
     1921 cagtattgaa acaaaaaaaa ttgaataact tatagactat ggaacgccta acatgacgtt
     1981 ccttttctat ttccagccgt tcttattgga cggctatttt attacccaaa atgaaaggag
     2041 cattagattt atgaaaaaga tgttaaaacg attgtgtacg ggcttcttag ctcttgcaac
     2101 tgtcgttact gctttaccga cgacacccgt ccatgcagaa agtaagcaat actggacgga
     2161 aagtgcagag cgtgtcggta tcattgaaaa agtaatgaat gacggttcta tcggttcgac
     2221 attcaatgag ggctatatga aagtcgaggg cgaaactgcc tattgtatcg acatcaacac
     2281 agattttaag aatggttaca agaccagagc tgacgcaagc tcacgcatga gtgctgacca
     2341 gatttcagat gtggcgttat ccttagagta tgtcaaacag tatggcgaag ctcacaagaa
     2401 actgaactac aagcaagtct atctgttgga acaatgtgta gtctggcaga gattgagcgt
     2461 acatcttggc tggcaatgtg ataacgtgcg agcttcttat gatgaaattc caaaagctac
     2521 gcaggacgaa gttttctctg gtgcaagagc ctttgtcaaa gaaaataaag gacgctatga
     2581 atgtggcggt tatatctact ctggcgaggg gcaggaattg ggacaattct gggcgaagct
     2641 gaatgttgga aatgcgaaac ttcaaaagac ttccagtaat accagcatta caaacggtaa
     2701 cggaaattac tctatcgctg gtgcaaccta tggtgtcttt gctgataagg actgcacgaa
     2761 acagcttgcc acccttacga ctgatgaaaa cggaaataca gacgttgcag aagtaaaagc
     2821 aggcacagtc tatatcaagg aactttctgc accagtagga tataaagtgg ataaaaaagt
     2881 ctatccattg acaatcaagg ctggcgaaac agcgactttg aacgtatctg atacaccaaa
     2941 agtaacagac actttgattg agcttttcaa gatggatatg gaaacacaga aagacaatcc
     3001 gcaggggaac gcttctctag caggtgcaga atttacatgg aagtattatg caggcttcta
     3061 taataaagac aatctccctg ccgaagctac tcgtacatgg gttacaaaga caatcgctga
     3121 aactgacagc aacgggacaa cccactacat cacaaaatta gcggacgcat acaaggtatc
     3181 tggcgacagc ttctatatgc aggacggcaa ggcggttctt ccacttggga cgctaaccgt
     3241 tgaggaaaca aaagctccaa acggctactt gttagacggt gcgtatatgc aggctggcga
     3301 taaatccgaa cagattaagg gcttatatgt aacacagatt accgaggacg gcgaccttgc
     3361 cgtattaact ggaagtaacc agttttccgt atctgacaag gttatccgtg gcggtgtcaa
     3421 aattcagaaa cgagatttag aaacgggcga tacaaagcca caaggaagtg ccactttgaa
     3481 agatactgct tttgacatca tttccttaaa tgataatgca gtattggttg agggcaagct
     3541 atacaagaaa aatgaagtgg taaagacaat tcgtacagat attgagggtg tcggttctac
     3601 ttctgccgac ctcttacctt atggaaaatt ccgtatcgtt gaaagtgaag ctccaaacgg
     3661 atatttgaca gacggtgcaa agccgattga ttttacaatt acagaaaatg gaaaaatcgt
     3721 ggacttaacc gacgaagccc attctatcta taatcagatt aagcgtggag atattgaggg
     3781 cgtaaaaatt ggtgcaggca cacacaagcg tcttgctgat gttcctttta ggatcacaag
     3841 caagacgacg ggcgaaaatc atgttgtggt aactgatgat aacgggcaat tctccacttc
     3901 tgctgaatgg gcttctcaca agcacaatac caacgcaggc aagaccaccg aggacggtgt
     3961 gtggtttgga acttctgaac cagacgacag caagggtgca ttaccttatg atacctacat
     4021 cattgaagaa atgcgttgcg aaagcaacaa aggctttgag cttatcccac cttttgaaat
     4081 cgtggtatca agaaataacc ttgtggttga tttagggact ttgactgatg aatacgaaaa
     4141 agaaatctct atccatacca cagcgaccag caaagacggc gaaaagacta tccttgcagg
     4201 aaaagaggtt acaatcgttg atactgtcaa attagaggga cttaccaaag gcacaaaata
     4261 ccagctcaaa ggctggcaga tgttaaagga agaaaacgcc gagcttatca ttgacgggaa
     4321 acgtgtagaa aacgattata cctttgtcgc tgatgatgaa gaaataaaag tggaaatttc
     4381 ctatacattc aatgcgtctg ctttaggtgg caagaacctt gttacctttg aggaattgta
     4441 tgatttaagc aatccagacg aacccgtgaa agttgcggag cataaagaca ttgaggacga
     4501 agggcagacg gtacttatca cagagcgtat catcaagata catactaccg ctaccgataa
     4561 ggacggcaac aaagagcttg aagctggaaa aaaggtaaca atcattgata ccgtaacctt
     4621 agagggctta gaagtcggta cacagtacaa acttgtgggc tggcagatgt tgaaagaaga
     4681 aaatgcagaa cttcttatca atggaaaacg tgtggaaagt gattacactt ttactgctga
     4741 cagcgaaact atgaaagtgg aagttgcttt tacgtttgac gctacttctc ttgacagtaa
     4801 acagcttgta acttttgaag aattatatga tttgagcaat ccagacgaac cgaagaaagt
     4861 taccgagcat aaggatattg aggataaggg acagacaatt acctttaagg aaaagccaga
     4921 agaaccagag aaacccgaaa caccaccgac accagaaaag cctaacagac ctagcgacag
     4981 tcccaaaacg ggcgacagta caaatgtaat ggtatttatc gtgatgttgc ttgcgtctgc
     5041 tggtggactg gctggaacat atctttacaa acgccgtaaa atgaagaaat cataaggcgg
     5101 taacgatatg atgaaagaaa aatcacgctc tccgccgaag ctgtcaaacg gcagacttcc
     5161 gcttattctg gcttgtctgc ctacaacctg caagaacaca gatagtcaag ggtgcgtaag
     5221 cattgatttt accctttact atctggggga ttgctggtac ttcccgaacc gccagaataa
     5281 gaaatcacaa tcaatttatc aaaaatagaa agaaacgagg taaaacacta tggaaatgaa
     5341 atatgtcgtg ccagatatgg cacagtcttt tggaactctt gaatttgcag gcgaaagcga
     5401 gccagtcttt gaaagagata aaaataatcg cagggtctta gccagacgaa gctataacct
     5461 ttattccgac gtacagaaag gcgaaaatgt tgtggtagaa attcccgtgc aggctggcga
     5521 aaagcatttc aagtatgagc agaaagtaaa acttgtcaat ccgaagttat acggcagagg
     5581 ttacgcaatc ggggatatgg gacataccga ttatgtatta gttgctgatg atattgtagc
     5641 agttgaagaa aagtaaagga gtgaagaatt tatgagatta tcaaacgggt ttgttattga
     5701 caaagagaaa acatttggag aattaaaatt tacagcggtg cgtgatgtgt tcttgcagaa
     5761 tgaggacggg acaccgagta cccagcttaa aaagcgtatc tatgatttga aatgcagtct
     5821 gcatggtgga attatccccg tgtccgtacc gccagaagta ccgttaaggg aatttcctta
     5881 caatgcagtc gtggagcttg tcaatccagt agccgatacg gtatcacgaa agacctatac
     5941 gggtgcagat gtggactggt atgtaaaagc agaggatatt gtgttgaaga ataaaggcaa
     6001 tcagaacgca ggcaatccac aatcccatac accgcaagga cagccgaaaa aataaaatta
     6061 gagattagat ttttattgtg aggtaattcg ttgaatgata taattaggat aaattgtgag
     6121 gtgcttatct atgaaagtat tagttagttc atgtatcatg ggaaaaaact gcaaatataa
     6181 cggtgggaat aatctcaatc cgaaagttgt agagtttcta aaagacaaag aggttatcga
     6241 aatttgtcca gaattattag cgaatatgcc tacaccacgt cctagtgcgg aaatagtaaa
     6301 tggtattgtc atggatataa atggaaatat tgttgatgag gaatatcgtc atgcggtaca
     6361 gttggcttta aatgaaataa gaagtatgga aatagattta gttattctgc aatcaagaag
     6421 cccaacttgt gcagtcaaga atatttatga tggtagtttt acggggaaat tgataaaagg
     6481 tcaaggtcta tttgcacaag cgttaattga ggctggatat aaagtgttgg actcagaaga
     6541 tttttaataa atggtaatgg aaaagcagtt agtcttaaga ttgactgctt ttttcatacc
     6601 cagaaaggag tgaacgattt atgcgtaaga tttggaacaa aggacaccgt atcagagcca
     6661 gcgacaagca ccttgtctac cacttttcca tagggacgct tctgtttgta ttcgtggcgg
     6721 ttcttctgct actgaatagc aaacagctca tgcgtaccga ttgggagcat ttcagcttgt
     6781 tagaaaatgg cttgacgctc tccccttaca atttcataac tatactgata gcgactggtg
     6841 tttgtgcatt ggtcgctttt gggtattacc gcatctgtta cgaccatttc aagaagctcc
     6901 tgcaccgtca aaagttggca agaatggtac tggaaaacaa gtggtatgaa gccgataccg
     6961 tacaagacag cggttttttt actgacctgc aaagcagatc aagggaaaaa atcgtctggt
     7021 ttccgaagat ttattatcaa atggaaaagg gactgcttca tatccgctgt gaaattacgc
     7081 tgggaaaata tcaagaccag cttttacggt tagaggataa attggaaagt ggcttgtatt
     7141 gtgaactgac cgacaagacc ttgcatgacg gttatatcga atataccctg ctttatgata
     7201 tgatagcgaa ccgcattacc attgatgaag tacgggcaga aaacggcagt cttagactga
     7261 tgaaaaatct tgtctgggaa tatgacgcac tccctcacgc tctgattgct ggtggaacgg
     7321 gtggcggtaa aacctatttc ctgctgacgc tcattgaagc cttactgcat accaacgctg
     7381 tcctttatat cttagacccg aagaatagcg accttgcaga cttgggaacg gttatgggaa
     7441 atgtgtatca cgccaaagaa gaaatgattg attgcgtcaa tgctttttat gagggcatgg
     7501 tacagcgaag cgaggaaatg aagcgacacc cgaactataa gacgggcgaa aactacgcct
     7561 atctgggact tccaccctgc tttcttatct ttgatgaata tgtggcattt tttgaaatgc
     7621 tggggacaaa agaaagcgtg agcctgctta gtcagttaaa gaaaatcgtt atgttaggac
     7681 ggcaagcagg ctatttcctt atcgttgcct gccagcgtcc agacgcaaaa tattttgggg
     7741 acggtatgcg tgaccagttt aatttccgtg tgggacttgg gcgtatcagc gaattgggtt
     7801 acggtatgct gtttggttca gatgtgaaaa agcagttttt tcagaagcgt atcaagggac
     7861 gtggctattg tgatatggga acaagcgtga taagcgaatt ttacacgcct ttagtcccga
     7921 aaggacatga ttttttacaa acaatcggca ggcttgcaca agaaagacaa gttatgccag
     7981 aacaacaagg aaaggagaac taagcaatga aagaattaga aatctataat atacagacaa
     8041 ggcgaatgat gaaatatgtc tgctttcatt atgaacaatt tgaagcggac tgtgataagt
     8101 tgaccgtgga aagatataaa aattttactg ttaatcctaa aaatcgtttt gaaaccagaa
     8161 tggaaaaagt gacagaacag cttctttctg gggaaagagt tattcccagc cgtctttgct
     8221 taagactgga aaaccgtcat tctatctgta actgccgtat tgattatgtc tttgaaatat
     8281 ttgatatgaa atcacttcga gaagatattc gtaaagaaga tttttcagca gaagaatgga
     8341 ttacgtgcga aaagtctaat gttgattatg tactgattta cattggaatg aacaagtaat
     8401 ccataggaac ggtgcttggc ggtaacaaac cgtcaagtgc cgttcctgtt ggtcgggctt
     8461 gtcccgacca acagataaaa cccctcggta tctaacagag gggtacgttt gcaaatagac
     8521 aatagacgaa aaacacagga aacataaggc ttatcgcatg gtttcctagc aaaaatcggc
     8581 tgtgaagtcg ccttaaaaaa cttcacactt gacagattgg gggtatggtt ctgaatgaag
     8641 aacaatggat aaaagaatta cgggaaaaac ggattgctta cggtatctca caaggcagac
     8701 tggcggtggc ttctgatatc acaagggaat atctcaacaa gatagaaagc ggaaaaatga
     8761 agccgtcaaa ggaacttctg gaaactctgc ataaagaact ggcaaggttc aatccagaag
     8821 caccgcttac catgctgttt gattatgtaa aaattcgttt tcccacgctg gatatacagc
     8881 acatcatcaa agatatatta aaactgaata tcaattatat gctccatgaa gattacggac
     8941 attacagtta tacggagcat tattctttag gggacatctt tatctatacg tcggctgacg
     9001 aagaaaaagg tgtcctttta gagttaaagg ggcgtggttg caggcagttt gaaagttacc
     9061 tgctggcaca gcaaagaagc tggtatgact ttcttatgga cgcactcgta aacggtggcg
     9121 tgatgaagcg tattgacctt gctatcaacg accatacggg cattttggat attccagagc
     9181 ttgcggaaaa atgcaggaaa cgggaatata tcggaaagtt cagaagctat aagttttatc
     9241 agtcgggcga gcttatcaag catagagagg acgacagaga atatatggga cgcacccttt
     9301 atcttggttc gctgaaatca gatgtgtatt tctgtatcta tgaaaaagac tatgagcagt
     9361 atgtcaagtt agggacacct ttggaaaaag ccgaaattat caaccgtttt gagatacggc
     9421 ttcgcaatga acgtgcttac tatgcagtac gggatttgct gacctattat gacgcagagc
     9481 agaccgcctt ttctatcatc aaccagtatg tgcggtttgt tgatgaagaa cccgacaagc
     9541 gaaaaaatga ctggaaactc aacgagcgct gggcttggtt tatcggggat aatcggcaaa
     9601 gtctgaaact gacgacaaag ccagagcctt ataccttaga ccgcacgctt cgttgggtac
     9661 aaaggcaggt agcaccgacc ttgaaaatgc tgaaaaggat tgataaggga aacggaacag
     9721 actacatgaa aactatcgaa cagcaggcaa agctcacaga aaagcatgaa atgataatca
     9781 aacagcagac gacccctgca aaagatttag tagaaagtta ggagtgatga aaaaatgtgg
     9841 gaattattga aagacttcct gctggtatct gttggaacgg gtatcggcgt agccttgatg
     9901 tgtattttaa gtgttggcaa agaagctgac tatgaaatga agaaattaaa agaaagcgag
     9961 gacaaataac atgaatttcg ggcaaaattt gtatcaatgg tttttaagca acgcacagag
    10021 cttagtgctt atgtcgattg tggttatcgg tatctacttg gggttcaagc gtgagttttc
    10081 aaagctcatc ggcttcttgg tagttgcctt gattgctgtc ggtttggtgt tcaatgctgg
    10141 cggtgtgaaa gatgtactgt tagaactgtt caacaagatt atcggtgcat aaatttttat
    10201 tgtggtgcta atatgcgaat gttataatat ggatatataa aattttgatt tatgggggta
    10261 ttcttttgaa gaaagcaatg atatatgttc atggtaaagg tggaagttat cttgaagccg
    10321 aacagttcaa aaatatttgt ttagattttg atgtttttgg agtagattat aatgactatt
    10381 tcccgtggat tgtaaaaaat gaaattatgg aagtctacga taagatatct gaaaaatatg
    10441 actatatata tgtacttgct aatagtatcg gagcttattt tacaatgcac acattacaga
    10501 atttcaagat tgaaaaagca ttattcatat cgcctatact tgatatggaa caacttatag
    10561 tagatatgat gagctgggcg aatgtgtctg aaaaggaact ttctgaaaga aaagaaatac
    10621 caactgattt tggcgaaaca ttatcgtggg aatatttatg ttttgttcgg gaaaacccga
    10681 taaattggaa aacgcctacc gaaattttgt atgctgaaca tgataatctt acatcacgtc
    10741 aaacggtaga taaatttatt gatagacatt gtgcaaatct taccgttatg aatgacggag
    10801 aacattggtt tcatactaac gaacagattt tctttagaga taattggcta agaaaagtta
    10861 tacaatagaa tttagatttt atatccatac acacaaagca gttagtctta ggattgactg
    10921 cttttttctt acctaaaatc agattggagt gatgaaatga gcgatatttt taaggatatg
    10981 caggcaaacg tcggctgtga ttatatttct aacctgccct cttacaagcg taaagtgtgg
    11041 catgaaatga agcgattacc gcttacgaat tatgatataa aacagttaga agatttttca
    11101 aagtatgtgt ttggtatgtc gtaccagagc ttaaaagatg tgatgaaaca acagaaagga
    11161 cgtgaggaac aatgcaggaa acaagggtgc tggtggaaac gagaggaaca actggcaaag
    11221 aaacaacatc atactggttc gacctaccga tagatgttgc cgagtttgaa gaaaagttag
    11281 gtgtcggtgc agaaagtcaa gattaccgca ttatcgaaaa ggtgttgcct tatgctgatg
    11341 aagtccacga acaaacaagc gtgtaccagc tgaatgaatt agattttatg taccgccagc
    11401 taccagccga tatgcaggaa gaatatatag cacttcttac cgtgtttgaa aacttagaag
    11461 cactttatat ttgcaggaat gtaattacag tttatccaga ctgtaaaagc atgatagatg
    11521 ttgcaaaaca aaagctgatg aatgacccga cattcaaaca tctgtccgag gactgtcaag
    11581 catactattt tgactttgaa gcctacgctt ctcacttgct ggaaaataga cgctatcttg
    11641 taacggaaca tagtgtcttt gaactgccag cgtaggaaat gaggtggtgc ttatgattga
    11701 tgatatggca gtttatattg ctaatcttgg caaatataac gaggtctatt tagtgggtgc
    11761 ttggtttaca tttcccattg acgaggaaga tgtgaaagaa aaaatcggct tgaatgaaca
    11821 gtatgaggaa tacgcaatcc atgataccga caacttcccc attgcgattg gcgagtatgt
    11881 ttccattgat gaactcaatg agatgtatga aatgctagag gaacttcccg actatattgt
    11941 agagtgtctg gatgaattta tcggtcatta cgggacgctg gaagaagtcg tggaacacaa
    12001 ggacgatatt tactattatc ccgactgtga aaccatgaca gacgttgcct attattacat
    12061 agacgaattg caggcactag gcgacattcc acccagcttg cagaactaca ttgactatga
    12121 agcctacggg cgagatttgg atattggcgg ttgcttcatt gaaacaagcc gaggtatgtg
    12181 cgagatacca tattaacgct ggaagatcag caacaagcat tgttgctact gacagcgtat
    12241 ttctctttaa gagacagtct gaaacatggc tgtccttttc tctttgaaga acttacgaaa
    12301 ggggctgaaa gaacttgaaa aagattaaaa gctacacggg tatctggaac gtggaaaaag
    12361 tcttatatgc aatcaatgac tttaacttac cctttcccgt tacctttaca cagattacat
    12421 ggtttgtgat tacggaattt atcatcattc tgtttgggga tatgccccca ctttccatga
    12481 ttgagggagc atttctcaaa tacttcggta ttcccgctct actcacttgg tttatgtcgc
    12541 agaaaacctt tgacggaaag aagccataca gctttttgaa atcacagata acctataccc
    12601 tgcgacctaa aatcacttat gcaggaaaag ccgtaaaact gcataagcag atattgaatg
    12661 aaacaatcac ggcagtaagg agtgtgaacg atgttcccga taaaatatat tgacaacaac
    12721 cttgtctgga acaaggacaa tgaggtgttc gcctactatg agctgatacc gtacaactat
    12781 tcttttctat ccgcagagca gaaatttatc gtgcatgaca gttttcgaca gctaatcgca
    12841 cagtcccgtg agggaaaaat tcatgcgttg cagattgcca cagaaagctc aattagaagt
    12901 atgcaggagc agtcaaagaa gctggtaacg ggaaaattaa aggaagttgc ttaccagaag
    12961 atagacgagc agaccgaagc gttagtatct atgattgggg acaatcaagt ggactaccgc
    13021 ttttttcttg gctttaagct catggttacg gaagaacagc tcaatctgaa gaacatcaaa
    13081 aaatcgacat ggctgacgtt caaggaattt ctccatgaag tgaaccacac gctgatgaat
    13141 gactttgttt ccatgccgaa tgatgaaatc aaccgttata tgaaaatgga aaagctattg
    13201 gaaaataaaa tctcccgtcg ctttaaggtg cgtcgcttgg aaatccatga ttttgggtat
    13261 ctcatggaac atctttacgg cagggacggt gtcgcttatg aagattatga gtaccagcta
    13321 ccaaagaaga actacaaaaa agaaacgctg ataaaatact acgaccttat ccgtccgaca
    13381 aggtgtgtga ttgaggaaag ccagcggtat ttacgcttgg aacatgagga caaggaaagc
    13441 tatgtgtcct attttaccgt caatgcgatt gtcggggagc ttgattttcc gtcaagtgaa
    13501 atcttctatt tccagcaaca gcagtttatc tttcccgttg atacttccat gaatgtagaa
    13561 atcgtggaga accgaaaagc attaacgacc gtccgcaaca agaaaaaaga attgaaagat
    13621 ttggataatc acgcctatca agcaggaaat gaaaccattt caaacgtggt ggacgcttta
    13681 gacagcgtgg acgagctgga aactgactta gaccaaagca aagaaagtat gtataagtta
    13741 agctacgtga tacgggtgtc tgcacccgat cttgacgagc tgaaacgccg ttgtgatgaa
    13801 gtcaaggact tttacgacga cttcaatgta aaactggtgc gtcctgctgg ggatatgctg
    13861 gggcttcatt cagaattttt acctgccagc aagcgatata tcaatgatta tgtgcagtat
    13921 gtaaaatcag attttctagc agggcttggt tttggtgcta cacagcagtt aggagaaact
    13981 acgggtatct atatgggcta ttccgttgat acgggaagaa atgtgtacct gcaaccgtct
    14041 ttagcttcgc agggcgtaaa aggaacagtt acaaatgccc ttgcttctgc ttttgtcggt
    14101 tcgcttggcg gtggaaagtc attctgcaac aatctacttg tatattatgc ggtgctgttt
    14161 ggcggtcaag cacttctgtt agaccctaaa agtgagcgtg gaaactggaa agaaacactt
    14221 ccagaaatcg cacatgaaat caatatcgta aaccttacca gcgataagga taatgcagga
    14281 cttcttgacc cgtttgtgat tatgaagaat gtaaaagacg ctgaaagtct ggcaatcgac
    14341 atcttgacat tcctcacggg tatttcctct agggacggcg aaaaattccc cgtacttcgt
    14401 aaggcggttc gttccgttac ccagagtgaa aatagaggac tgttacacgt tattgaggaa
    14461 ttgcgaaagg aagatactgc tatctcacgc aatatcgcag accatatcga cagcttcacg
    14521 gactacgact ttgcacacct gctgttttca gacggtacgg tggaaaatgc tatcagcctt
    14581 gataaccagc tcaatatcat tcaagtagcg gacttagtat tgccaaataa agataccacc
    14641 tttgaggaat acacgaccat tgaattgttg tcggtgtcta tgctgattgt cattagtacc
    14701 tttgcccttg attttatcca ttcggataga agcattttta agattgtcga tttggacgaa
    14761 gcgtgggcgt tcttaaatgt ggcacaagga gaaacactct ctaacaagct ggttcgtgct
    14821 ggacgagcta tgcaggcagg cgtttatttc gttacacaat cttctgacga cgtgtcaaag
    14881 gaaagtctga aaaacaatat cggcttgaag tttgccttta gaagcacgga tataaatgag
    14941 ataaagcaga ccttagagtt tttcggtatc gacaaggacg acgagaacaa ccagaaacgg
    15001 cttcgtgatt tggagaacgg acaatgctta ttgcaggact tatacgggcg tgtgggtgtg
    15061 gtgcagatac acccagtctt tgaagaactg ttacacgcct ttgataccag accgcccgta
    15121 caaagaaatg aggtggagtg atgaaagaaa ggctaaaggg gcttctgaca aaacggaagc
    15181 tctttcattt tgtcaaagtg gctgtgctgg caatctttat cagcatagtg tttctctctc
    15241 tgcttgggac ggtggctcat gcgacggggc ttgtggacga cactgtcaat acagaaaatc
    15301 tgtactcaaa atatccgctt tccaattacc agcttgattt ctatgtggat aatagctggg
    15361 gctggctacc gtggaactgg ctggacggta ttggaaaatc ggtgcagtac gggctttact
    15421 gtattaccaa ctttgtctgg acgataagcc tttatttgag caatgcaacg ggctatgtgg
    15481 tgcaggaagc ctataaactg gacttcatca acgatatggc agacagtatc ggacagagca
    15541 tacagaccct tgcaggcgtt accgagaacg gcttttcttc tacgggcttc tatattggtt
    15601 tcctgcttct cattatctta gtggtgggaa tttatgttgc atatacggga ctgataaaaa
    15661 gagaaaccag caaggcactt cacgctgtta tcaactttgt ggtggtgttc gtgctgtccg
    15721 cttcatttat tgcctacgct cccgactaca tcaagaagat aaatgaattt tcatcagaca
    15781 tcagcaccgc ttctttggac ttgggaacaa aaatcatgct ccccaactct gacagtgagg
    15841 gtaaagacag cgtggacttg atacgagaca gcttattttc tattcaagta gaacagccgt
    15901 ggctactctt acaattcggg aacagcaacg cagaagaaat cggtacagac cgtgtggaag
    15961 ctctggtatc ggcaagtcca gaggacgagg acgggaaaac cagagaggaa gtcgtgaaaa
    16021 cagagattga ggacaacgac aacaacaatc tgacaatacc gcaggtagtg aaccgtttgg
    16081 gtatggtgtt tttcctcttg ttcttcaact taggtatcac gatatttgta ttcttgctta
    16141 cgggtatgat gttgttcagc cagatacttt ttattatctt tgcaatgttt ttgcctatca
    16201 gctttctact ttccatgata ccgagctatg aaagcatggc aaagcaggca atcgtgaggg
    16261 tatttaatac cataatgaca cgggcaggaa ttacgctcat tgtaacggtg gcgttcagca
    16321 tttccagtat gttttataac atttccacag attacccgtt tttcatggta gcgttcttgc
    16381 agatagtgtg tttcgctggt atctatatga agctgggcga tttaatgagt atgttctctc
    16441 ttaatgctgg cgacagtcaa agcatgggac gcaggatatt ccgcagacta tatctgttta
    16501 tgcgacatcg ggctagacgt atggaacacc gtattgcaag gactgtaagt gctggcggtg
    16561 ttgctggtgc ggcggctgga agtgccgttg ctggcaaaag agccgaaaga aaaaatacgg
    16621 cttctaaaga aaatcggagc aatactactt ccagtatggg acagcgtgca ggctcaaagg
    16681 tgggtgctgt cttagacacg aaaaataaag tgaaagacaa ggcaaacgct gtcaaagaaa
    16741 atatcaagga tatgccgaca caaacagctt atgcggtata ttccgcaaag gaaaaggcaa
    16801 agtccagcgt atcagacttc aagcgtggca tggtgcagga acagcagtcc agacagacgg
    16861 gacgtttgga aaagcaggaa cagcgtaaga aaaatattgc tgacaagcgt atggagcttc
    16921 aaaaggcaca agaagtaagg caggcacagc gaaaggctga cggatcagcg acaacgggag
    16981 ctacccgtcc ccatgagaga ccagccacag cttcaaccat tccaaaaccg agtgctgaaa
    17041 aaatgcagga agtcaaacgc cctgccacag ctctgacttc taaagcaagt gagccagtca
    17101 agacaaatgt tatcaaagag cgtccgctat cttcgggtgc ttctgataga aaagcgaccc
    17161 agtcggcaca gccagtacat aggcagaatg tagaaaaagt ggtatcgcag gaaacacgcc
    17221 agaatgacac caaagaccgc agaataaagg ttcagcagac gcagagcgtc cagaagaacc
    17281 agcagaccac agagaaaagc cgtaaccttg taacaaagaa aggacagaag aaaaaatgaa
    17341 attgaaacat atcgctctta ttggaagtct gtttcctatt ctcttttctc tggtgctttt
    17401 ctttggtgtc ttgattagtg cggacagcga cgacgagaac agcaactttt cttctagcat
    17461 tacgggtatg aacctatccg cagaagtctt aaaacatcag cctatggtag aaaaatacgc
    17521 cagagaaaac ggtatctccg agtatgtcaa tgtgttgctg gctatcattc aagtagaaag
    17581 tggcggtacg gcagaagatg ttatgcagag ttcggaaagt cttggtttac cgcccaactc
    17641 tttagatacg gaaagctcaa tcaagcaggg gtgtaagtat tttgcgtccc tgctttcttc
    17701 ctgcaaaaat caaggtatgg acgacttgaa tgtagcgata cagtcctata actatggcgg
    17761 tggctatgtg ggatatgtgg caggaaacgg aaagaaacat acatacaatc ttgcagagag
    17821 cttcgcccgt gagaaatcgg gtggaaagaa agtaacttac accaacccga tagccgttgc
    17881 gaaaaatggt ggctggcgtt atcagtatgg caatcaattt tatgtggaat tagtcaatca
    17941 gtatttaact gttccgcagg tatcgggaga gctgacacaa aaggtcatga atgaagcgtt
    18001 gaaatatcaa ggctggaagt atgtgtatgg cggtagcaat cccaacactt cctttgactg
    18061 ttcgggactt acgcaatggt gctatggaaa agctggtatc tccttaccga gaacggcaca
    18121 agcccagtat gacgcaaccc aacatctgcc actctcgcag gcaaaggctg gcgatttggt
    18181 atttttccat tctacctata acgctggtac ttatgtaacg cacgttggta ttcttgtttc
    18241 gccgacgcag atgtaccatg caggaaatcc gataggatat gcagacctaa gtagtagtta
    18301 ctggcaacag cacttaatcg gtgcaggacg aataaaacaa tagaaaggac ttgaaaaata
    18361 tgtttaagaa gaataagaaa cagacagaaa ctatcaaaga accaaaagaa aaaaaggtgc
    18421 gtactgtcaa ggtaggcaca cataagaaaa ccgtgattgc gttgtgggtg gtgcttatcg
    18481 caagcgtgag cttcggggtg tataagaatt ttacggctat cgaccagcac accacccatg
    18541 aaaaagaaat cattgagctt cgcttgcagg acaccaacgg gataaaaaat ttcgtgaaga
    18601 attttgcgaa gtcctattac acatggaata acagcaaaga agcgattgaa gcaagaacgc
    18661 aggcaatcaa cggttatctg acaaaggaat tgcaggactt gaatgtggat accattagaa
    18721 ccgatatacc gaccagttcc acggttacag atgtgattgt gtggaatatc gaacagtcgg
    18781 gaacggacac tttttctgcc acctacgaag tagatcagca gataaaagag ggagaacaga
    18841 caacagcaat taaagcaacc tataccgtga aagtccatgt ggacgctgac ggggatatgg
    18901 taatcgttca gaaccctacc cttgcaccag caatcgaaaa atcagactat gagcctaaaa
    18961 caccagaagc agacgcaagc gtggacgctg ataccgtaaa tgacgctacc tcatttttgg
    19021 aaacattctt taagctctac ccgacagcta cagaaaaaga acttgcttac tatgtatcgg
    19081 gaaatgtgct tgaacctatc ggcagggact acttttattc tgaattggta aaccctatct
    19141 ttacaaagga cggggacaat gtaaaagtca aggttgccgt gaagttcctt gataatcaga
    19201 caaaagcgac gcaggtatcg cagtatgaac ttgtgctaca taaggataat aactggaaga
    19261 ttgtaggata agcaaatatg gcgtgcattt ctataagaga tttgcacgct atccatgtta
    19321 taaggaattg acaattctta tttttcgcat tatactattt atgtaaatat gaaaaatatg
    19381 attcgtaaat aaatatgata agaaggagga aaatgatgaa aaaaggacaa catatttttg
    19441 gaacggtaaa agttggagaa cggggacaaa tagttatccc aaaagaagcc cgtgaaattt
    19501 ttgatattaa cgctggcgat acacttttag ttcttggcga cgaagaacaa ggaatagcga
    19561 ttgtcaaggc ggatgtgatg aaagaactgg cagtaaaaat tttaaaaggg cttggtagtt
    19621 tgagtggtgg gtttaatgat gaaaaatagc atttctctat tcttaccatt agccttattg
    19681 ctggatttaa ctattccttt tttcctcgct ccgttttata aaggttatag tcattctatg
    19741 caggtaatga gcgtgcttgg aaataacaaa tctccactac attttatata caacttatgg
    19801 ctagttttat gcggtatcat tcttttaatg agcggtttta aggtttatga aattgtttcg
    19861 cagaaatcaa aaaacatagc tgttattttg tttatagtca tattgatata tgcgataggt
    19921 ggctgtattc tctcagggat tttttcggta ggagaaacaa aatctctcaa tactatccct
    19981 gaaaaaatac atggttacgg ggcggttctt agatttatat gtttaacttt tgctccgctt
    20041 ttgattagct tatattggtt tcggattgag gaaataccac ttgcactatt ttcaatgatt
    20101 tgttttcttc tagcatttat cttttttacg atttttgtta tggcagataa accaaactac
    20161 aaagatacaa tcatagcttt tgagggctta tggcaacgat tatcactact gtttatgtat
    20221 ttacctttgg ggtgtttaat attactggaa aaataaatta ttaggagtga actctatgat
    20281 aggactaaaa aaacgagata ttaaaaaagc cttgagagct ggtgcaaaag ctggcggtat
    20341 gtcattggct gatgttcggg cggatattga agcgacaatt gatgaagcta tgaacagcac
    20401 cgacccagag gtgcaggcaa atttcaaaaa aaattttgga aataaacgcc ctgcaccaga
    20461 agaatatatt tatataatta caaagaaaac agttaaaggg ctgaaagtat gaaaatagaa
    20521 cgtctgatag gaataatctt ttatttaata aatagagagt gtgtaacaac aaatgaatta
    20581 gcacaaaagt ttgaagtatc tcgcagaacg attttacgag atattgatac actaactctt
    20641 gctggtatac cgatttattc tgagttaggt gtaaatggtg gctatataat aaataaagat
    20701 tttaaggttg atgaaaaaat tattgacagc aacaataaag aatatatttt gcttgcttta
    20761 aatagtctaa gaactgttta cggaaataaa aagatcattg aaacttacga aaaaatgaaa
    20821 catctttata acgatgtcaa tattaatgca cttccagatg ttgatttctc tgttgtaact
    20881 gaaaatccac aaattataag gtgcgtagac ttaatcaata aagcaacaaa agaacagcga
    20941 actataaaat ttatatatac taattcagca ggacatacaa aaaaagtttt tctaaaccca
    21001 ttacatacat attataggtg gtactcctgg tatgtttttg gatatgacac ctctaaaaat
    21061 gattatcgca tgttcaaagt ggtaagaatg aaaaatattt ctttaacaaa agaacttttt
    21121 caaaccaaag ataatatagc tgacctttta tctgattttg aaaaaagacg caaccagaca
    21181 aatattacgg ttactctatc ttataaacaa gaaatagaca ccttagttaa tgaatacttt
    21241 aaaggaaaaa ttgttgaaac tgtcaatgac tgttttataa gagaaattga gattaaagaa
    21301 aatgatttta tgacattctc aatcctttta ggactttgcg ataaagtaaa aatattatcc
    21361 cctcaaaaat acaaagaaaa ggtattaact catatcagaa aaataaagaa aaatttcact
    21421 taatagtgac atacatttgt cactattcct gctatataat tttcttatat cgaaaatatg
    21481 aggagatgtg aaaatgaaaa aagtatatgt atatttatta gacgacatgg cagaatgcga
    21541 aattggttat attttacaag cattcagtat ggaaaaatta ttaaaaaatg gaactaaaga
    21601 atttgaagta aagacagttg gttttaataa agaacccgtc ttaactttag gaggattaac
    21661 aattgttcca gattatagta tatcagaagt tgacttcaat gctagtacag ctctgctttt
    21721 accgggttct tccacttggg gaagtaaaga aaatcaagaa atattggaaa aagcacaaga
    21781 atgtttaaac aaaaatattt tagtaggtgc tatttgtggg gcaacactcg cacttgctga
    21841 ttatggtata ttagataaat ttaaacacac aagtaattct ctagaatatc taaatttctt
    21901 ttcaagaaac tatgcaggac agagcttgta cgtttgttct aattccgttt tagacagaaa
    21961 tttagtaaca gcaaattcag caggttcatt agaatggacg aaaaatattc taaattacct
    22021 taatgtgtat tctgacaata aaattactgc tttttacaat tattactcga caggaaacgc
    22081 aaaatactat gatgaacttt taaaataaag gtggtgtttc tgtaatgaaa caatcatggg
    22141 tattatgccc atctgcaata acaagacacg aacaaaaata cgggtagata cggaactgat
    22201 aagtttccct ttgttctgcc caaagtgcaa gcatgaaact ttaatcaata taaagcatgg
    22261 aaatgtaacg actattaaag agccagacgc taagacgcag agccgataat ttataggtta
    22321 ttgtaactta tagattgttg gctcttattt gttacctgcg gagcggatca gcaaataagt
    22381 tttggaatat aatggaaaaa catttatata aagaaaagaa gaaacatgaa aatattagta
    22441 agtgcctgcc ttttacaata taaatatact aaaaaaatcg taaaaagatc ctcaataatt
    22501 catatatttt tactaatgaa agatcaatat gacataccaa agcgttattt gcttctattc
    22561 aaaagagtgt caatttcttc ttctgataat ttttgtttga aattaaacac attatctaca
    22621 gctgttccta aaagtcttgc caaagggctt agtaatgaaa tatcaggata tgtattgttt
    22681 gtttcccatt ttgacaccga agaagtagtt attccaagag catttgcaac ttgttcttgt
    22741 gttagacctt ttatttttct tagtttctga ataatatcac cgataaataa tttcattttg
    22801 tgacatctcc tttacttaat gaaaatatta tcagataaaa acttttttta acaatgcagg
    22861 tatcgcagta tgaacttgtg ttacataagg atagtaactg gaagattgta ggataaatca
    22921 aaaaatgccg tagctttatt ttgcatttat tgcaagttac acgctacggc tagattaaaa
    22981 tataatattt tgaaatcttc ataaaatctt taattttgct ttttatactt taactaaaaa
    23041 ataaggaaag ggtatgaaca attatgaaag caattttaaa aacaaataac ctatgtaaag
    23101 atttcaaaaa gcaaaaggca gtgaataatg tatctataac tgtccgtgaa aattcaatat
    23161 atgggctact cggtccaaat ggtgctggaa aatctaccac tttgaaaatg attacgggta
    23221 tgctccgtcc tactagcggt aaagttcttt ttaatggaca tgaatggaac agaaaagatt
    23281 tagaacagat aggagctttg attgaaactc ctccacttta tgaaaatctt tccgcagtag
    23341 aaaatttaga agtccgtgca aaattactaa atattcctaa aacccgaata gataaagttt
    23401 taaaaatggt agatttgcaa aatacaggaa ggaaaaaagc tggacaattt tcaatgggaa
    23461 tgaaacaacg tttgggaata gctatcgctt tgttgaatag tcccaaattg ttgattttag
    23521 atgagccgac aaatggatta gaccctatcg gcatacaaga attacgttct cttattcgtt
    23581 cttttccctc taaagggatt actgttattc tatccagtca tattctatca gaggttcagc
    23641 ttatcgctga tgatattggt atcatttcaa atggtatttt aggatatgaa ggacagatga
    23701 ataaagatga aaatttagaa aatctgtttg tagaagttgt aaggaaatca caggaggaac
    23761 gataaaatga aaaattatat atcttctgaa tatttaaaac ataaaaatac attcgcaaaa
    23821 aaattagtat ggttagctcc tatactaact ttatgtctga atatacttgc tcctatgtgg
    23881 tatcaacaaa attcgtataa ctggtggtat gtattcttat atcctggttg tttaacgcta
    23941 ttatctattt tgataattca aagagataac ggcaaattaa aatttagagc aattttgtca
    24001 ttgcctgttg acttaaaaaa agtatggtat gcaaaaataa tcacttgtat aatatacatt
    24061 gtacttgcaa atacaatttt gatgttatgc aatgttgcag gtggttttat cattcaacac
    24121 atttttgata tacctatgac aattagccca atgcaggcat tgttcggaac actttgcatt
    24181 attctggcaa gtatatggaa tattccatta tgcttgtggt ttacaaaaaa agtgggtgta
    24241 tttgccactc tcatattaaa tgtcggaatg agctttatgt tgggaacatt aggggcaaat
    24301 acaagttttt ggttcatatg tccttatagc tgggttactc gccttatggt tcccacatta
    24361 ggaatattac cgaatggaga atcagtaaca ggaagtgctt tatcaactcc tttaccgttg
    24421 gttattatga caatctgctt gtcattgctt ttactatata caatttcaaa gtcaacggca
    24481 aaatctttta taaagcagga ggttctttaa tgtttagtat tatcagatgt tttcaagcag
    24541 aatggcttaa aagcagacat acaccattac ttttagtcca tgtgcttttt ccgttaatag
    24601 gagctggtgt ttttgcagga tattttcata tatccggttg gagtgagatg acaaatgtaa
    24661 cgaccttttt agaggtgtta gcaattattt ttccatttgt tattggtatc gttgtaggta
    24721 tgatagtcga actagaaaat ggagcaggtc attttcagtt aatcttaggt acgatccgtt
    24781 cacgtatagc ggtatatatc ggaaaattag tatatcttat cgttttagca acctttgcaa
    24841 caatactttg tattttcttg tttgccgtac tctatccagt tatgccattt tcgttttata
    24901 taaaacctct tattatgttg atattgtctg taataccact ttatcttatt tccatacctg
    24961 ttggtttcag tttaggcaaa agtgtatcta tgggcatagg tattgtagga agtttattat
    25021 ctgcattgct agttacagga cttggagatt ttatctggaa attcctgccg tggggctggg
    25081 gtgtacgatt tatggattat tgtgttttaa gatatgttaa tgaggggcag tttcattcta
    25141 acttacccga atttcaacta ggttttatac tcatgctggt ttttacagta gtgctgttta
    25201 tcataagctt agtgtggttt cagagatggg aaggagtaaa agaaaatgag taaaaaaatg
    25261 atgatattgc tgtttgctgt tattatatgt ttatctcttg caggctgttc tttacaggac
    25321 aaaatcgggg actattccag agagcaatgc tatctgaata aggaaaatgt gacgcaattt
    25381 tcctataagg gaaatgacta cacgatttta gcggatactg tctctaatag tggactcggg
    25441 gaatggattg ggtatatccg acaacttgcg gctgtagacg aatcaggaaa aatattactt
    25501 caagaaaatc tcaaaactgc tacctttcag acgttggcag atttagcaga tttagtggat
    25561 aaagccccta atgacgccta tattattcca ttcttaaatg tgtatgcagc tcctaacgct
    25621 gacgactatc tgattgtaga tataaatgga gggtatcaca aagctgttat agatgaaaat
    25681 atcaaaggca cagatacagt ttttgacttt aaggatatag agcaatctat gagtggaaag
    25741 tttgaaatca atcctcaaaa tgcaacgcag cttctttgtg atgggacggt ttatcaagta
    25801 acttctgata ctgtatcaaa taatgaattg ggaagttaca ttggtattct tgcggagaat
    25861 gtcatattta atgcagaaac aaaaattcct ttgtcaaagg aggaactaag aaaaattgac
    25921 tggtatgggg aaaacgccgg acaacatcgg gaacaatgga tttacaaaga tatttatgaa
    25981 attcatggta cagaaaagac cgaagccgtt gcagtacaga taaatgaccg ctactatatt
    26041 gcaaagcgtc aatgaccgat ttttgttttt ctgcctttat ggattatgat atactaaaaa
    26101 agctaggagg cgatactatg gcaacaatcc ttatgattga tgatgaacga cctattttag
    26161 aacttgtgaa aaatggactg caaaaggacg gacatttagt tacagtctat acgtccgccg
    26221 cacaggttcc tcttgataaa ctgaacagat atgacttgat tatactggac attatgatgc
    26281 cggatataga cgggttttct tattgtgata aaatccgttc attagtggac tgtcctatcc
    26341 tctttctgac tgctaagaca atggaaaatg atattacatt cggtcttgga ttaggagcag
    26401 atgactattt gacaaaacca ttccgtatta cagaattacg ggcaagagta aatgcccact
    26461 tacgccgcga acaccgagaa cgacatatag ctcttacatt tgaccggata aaaattgatt
    26521 tatctgcaaa agaattacgg gtagataata taccagtgcc tttaacgaaa agtgaatatc
    26581 tgatttgtga gtatcttgct agtaacaaag gacaggtttt ttcaaaggaa caaatatacg
    26641 aagctacatt ttccctttat ggagaaagcg atagttctac aatctcgaca catataaaaa
    26701 atataaggtc aaagtttgag aaaacgggtg ttcagccaat cgtaacagtt tgggggatag
    26761 gttatagatg ggaataaaaa tgaaaacatc acttacaaga actttttata aatttcttgt
    26821 ttgtctactt ggcggactat gcttgtccgt tgtcgtccct tttgcctgta tgatgtttgc
    26881 ttccagtata gggcttgtaa cacttgcaga taataacgaa cggcaaacga aagctttagt
    26941 accgatacta actgcaacac caaatgtatc agatatacat tttcctactg gaactaaatt
    27001 tcttcgatta actaaaaact atggatacat agatacgaat atgagtgaag aagaaaaaga
    27061 aaaggcttta atgtttgcta aaacggggtt catggataca agtggtaaaa cacagtttat
    27121 tttcattact cgagatgatg aatatattgt tttacagtat gttataggtt ctcaatattt
    27181 aaatgcacaa tttaatcagt atttaccgtc cccagaaatt atgatgattt ctttaatcac
    27241 tataagcagc ttaggggtat gtgtttatct gactgttcat tttgctaaag agctgagaaa
    27301 agaattgaca cctattttag aagctaccaa agaaattgag aataacaact tagattttac
    27361 tatcggacat tctaaaatat tggaatttga aaacgtgatt atatcctttg atagtatgcg
    27421 aaatagttta aaagggtcat tagaaaaaca gtggcgaagt gaaaaagcac aaagagaaca
    27481 gattgcatct ttagctcatg atttgaaaac tccattaact gttatgcagg ggaacattga
    27541 cctattagat gaaacagaac ttgacgaaga acaaaagcta tatttatcgt atgcaatgag
    27601 tagctctgag cagatgaaac agtatataaa aattttgatt gatatatcta aagcatctgc
    27661 tggctatcaa ttacaaatgg aagatgtaaa ttttccagag ttttggaaac atgtcttatc
    27721 tcaaactgaa atcatctgca aagataaagg tattgttatt cagcagacac agcataattt
    27781 cccacagaat ataactgggg atagaatgtt actggaacga gcattgatga atttggtttc
    27841 aaattcttta gagtactcgc ctgaaaactc tacattatat atagatgtag atagcaagga
    27901 caattacttg aatatctgta ttacagactg tggctgtggc ttttcgcaag aggcattgga
    27961 tcacgcaaaa gaacgtttct atatggcaga ccaaagtagg agctctaaac tgcattatgg
    28021 aatgggttta tatattgttg atatcattat aaaacagcat aaaggaaaac ttctgctaga
    28081 taattccaca gaaaccaaag gtgccaaagt tactgtaaag ttaccattat aagagaacgg
    28141 cttatttgtc gttctttttt catatcttta agaaatcttc aaaattaggt tgtattcttt
    28201 gtttgaaggt aatggttata tgctattata cgggggattg tgtatgaagt gttttaagca
    28261 atttaccaaa aactcaagaa caacttaaca gcaatccatg cgctaataca actgaatatt
    28321 ttaatatctt agctcgtaca gactatatgt tttgtgcggg ctttttttgt acccgaaaaa
    28381 attttctaac ttttttcggc ttcagcttag caaatcacac cttgctgtac agatatggtg
    28441 cggaaagagg gataaacact tttcaagtca tagctggaaa gggggtgaga ttatgaagcc
    28501 gtctgatttc cagaaaacaa tacaatgtca atttgaatgt aagttaaaga aagttacaaa
    28561 aggcattgta agaaattatc agaaagaatt aaaacggaga aaaaataagg aaattccttt
    28621 ttgtgaactt ccagaactag tgattgaaaa attatccgtt ttagacgatt acgacagcga
    28681 ctatacatta ttcaatgtat gtggcaacga tattagtatt cttgatgatg aattggcaga
    28741 agccttgaaa aagctgtctg accgtaaccg tgagaactta ctcatgtact acttcttaga
    28801 aatgagcgat accgagattg ctaaattgca gaatatttcc agaagtggtg tatttcaaaa
    28861 tcggtataac tcattggaac ttatgaaaaa aatactaaaa ggagaaaagt aagaaatgaa
    28921 gcacattttt aagaaaccgt cattttatct gatttcgtca gctacggacg gagacgaaaa
    28981 agcgattgaa aagatactgg caatttatga cccgtacata tcaaaatgtt gtttgcgttc
    29041 actctatgat gaatacggta atgtttatat tgccgtggat atggaattaa aaggacgtat
    29101 cagagaagcc cttatcaaaa tgattttgga ctttgatata cctttagaaa ccgaggaaga
    29161 ataacaagca gtaaccgcag agcatgattt gttcaatccc ctctttcctg ctctgctccc
    29221 tgcttttaca tgaaagcaac acgctttcgc cacagctctt tgacaactga ataaagcaga
    29281 cagatacgtt tgtgagatag cgagccacgg ggactgtacg ccacgacctt ttcaaaagaa
    29341 agcgagcgac ccacgcagtg atccgagagc gactgttgga aaagtcgttt tgccacgacc
    29401 tatcctcaca gaataatgat acgtccgcat ggtgcggttc tgcccacaag aatgggaata
    29461 gttgagatac taacggagct ttccaaagcc gtctgcctgc ttgtaaaaaa tgacacacag
    29521 taaagggggt gcatagatta tgaacaatac tgatgtgcct atctgggaaa aatatacgct
    29581 gacgattgaa gaagcgtcta aatacttccg cattggcgaa aagaaattgc gtaaattagc
    29641 cgaagaaaat attgacgctg gctgggttat cgtgaacggt aatcgtattc agattaagcg
    29701 aaaacaattt gaaaaaatca tagatacatt ggacgaaatc taatgtcatt gagccgtaga
    29761 tatggtataa taaggtatag cgtatcacgg ctcattccat gacggaaagg agctttacac
    29821 tatgtctaat gtaaaacgaa aagacagtaa aaatcgcaat ttgcgtaatg gagagagcca
    29881 gcgaaaagac ggaagatacg tttataaata taccgatata tacggaaagc cacagtttat
    29941 ctattcttgg aaacttgtac cgacagacaa gacacctgct ggaaagcgtg atgatatatc
    30001 gttgagggaa aaagaagcac agataaaaaa agaccttaac gacggtatcg acacagtcgg
    30061 cggtaaaatg acagtctgcc agctctacga gaaaaagaac agtcaaagaa agaacatcaa
    30121 gagggctact gaaaaaggac gacagtatct tatgaacgct ctaaaaaatg acctgttggg
    30181 tatgagagcg attgataccg tcaaacagtc agacgctaaa gaatgggcta tcagaatgag
    30241 tgaaaaagga tatgcctata aaacgattga taactataag cgttccttga aagcgtcatt
    30301 ttatatggcg atacaagacg actgtatcag aaagaacccg tttgaattta agctaagtga
    30361 tgttctggaa gatgatacgg agcagaaagt tatccttaca ccagagcagg aaaaacacct
    30421 gcttgccttt atggaaacgg acaagattta cagtaagtat tatgatgagg ttgtgcttct
    30481 gctggaaacg ggacttcgta tttctgaatt ttgcggattg acgacgcata ttgatatgca
    30541 gaacagaata ctcaatatag accaccagtt attgaaagat agcgaaatgg gttactatat
    30601 tgaaacgcca aagactaaaa acggaaaacg tgaacttcca ttgacagaac gggcttatca
    30661 agcaatccaa agaatactag agaacagagg aaaggcacaa ccgttgattg taggtggtta
    30721 cagcaatttc ctattcttaa accgtgaggg cttgcctaaa gttgcaggaa actatgaggg
    30781 tatggtgcga ggattgatta agaaatataa caagtatcac acggataagt taccaaacat
    30841 cacaccacat tcattcagac atacttattg tacgaatatg gcaaatagag gaatgaaccc
    30901 aaacaccctg caatatctca tgggacacgc taacataacc atgacacttg gctattacgc
    30961 acacggtaca tttcaatctg caaaagcgga actggaaagg ctggcttgtt aatatcggag
    31021 cttatattta ctactcattt actacttttg gttgcatttt catgctggta aatgccagct
    31081 tatgcaaggt atcttccaaa aagaaaatac cgataaagcc ctaaaatacg ggatatatcg
    31141 gcatttacca acttatgaaa agataatcag aaatttagta agtttttata ataaaatctt
    31201 ataaatatta caataaaata tttttttcca tgatatacct tgataaaatc tctgcttctt
    31261 taagcagtaa ctttgagttg aatcattata gtgatttata acatttatag aaatgctgtt
    31321 atagatttat atttaaacac tacaaatgga aatttaacta ttataaaaaa caatcattag
    31381 ataaaatgat tcttacaaca aaagcacttc tattgtagat ttattagtaa ataataaatc
    31441 tacaatagaa aaaactagaa gtacagtatc ataaaaatat aattaactat acctctaaat
    31501 tattgttttt aaaataaatt tttattcatt aaaaaataca cataaatatt tctagactcc
    31561 gattcagcaa acttatataa gttcactttt tatttatcat caattatttt catatacttc
    31621 ttttatctca tcttcactta agtcaaaatc attaaattta tttaatatgt catctaattt
    31681 aaaaccattt tttttcaaca ttataattat tttataatct ttttcttttg caactctaat
    31741 tgctgtctct ctttcaatct cttctttaaa atttctactt ttattcatga tataagcacc
    31801 tcttttcaga tttaataaat attcttcatt gctacctaat tcttttaatc tatcaagtgc
    31861 ttttttaata atagaatcat tcttagctat aactcttaca tctaagttag aaggattact
    31921 aataagtttt ccccatagca taattctatt tactatatag tcagatttat gaatttttgg
    31981 aagctctata aaatataatg cagttttact agaataaata tctggatgcc cgtccattgt
    32041 taatctcagg caatttacat aatcttctat gtgattatat tttacatgat ttagtatatg
    32101 tattccaata gtttttccaa tttctttata ctctttacct tcttctaact ttctaccatg
    32161 tacacgacta agataatatt cagctctttc caaataatcg ttctcaaaag ctctttgcat
    32221 ctcaatattt atatgattat tttcttcatc ttcagccaaa atatcaagtt taggtctttt
    32281 ctctccaatg taattaattg ttggatcagt ttcaactcta attattctct ttatttgagt
    32341 gaacggtttg atattcctgt tagcatatgg agcatctttt agaatatcat ttataaaatt
    32401 tacaagtaaa tcatattcat tatttaaagt gaacaatgat ttaaatacct catcatactc
    32461 aggcttagca tatccatctt cagtcacaac ttctccaaca ttttcattag tcaaaatctc
    32521 ttttggaatt aatgccttga ttttatctaa ttcatcatta gaaaaactac ttctactaag
    32581 tatatcattt aattttttgg tccattcttt atctttttct tcaattatag ttcgcttata
    32641 ttcttttgat gttttaataa tcttagattt ttcttctact ttttctatca tttcaacacc
    32701 tctctttttc ctcttttgta tttatcattt cttgaaatta aactaagtca ctacctcttt
    32761 taaaagttct tgctccataa acactttctt aaactctaat gtctgtgtat gtacttgaca
    32821 ttctctctct atctaaagtt aaataaatta atctatgtat agaggataag tccaaaaata
    32881 acataaaaca ctaattaatc atttataaag cattaattaa tcactgacaa tgctgttatt
    32941 gtcaccacat agcaccaaca tagattcttc tattataggg caattatcta tgaaaaatag
    33001 actcataaga ttagaaaatg tacttaaatt ttagttcatt taaatattca ttttgaagaa
    33061 agaaatttaa ctttagacta aaaaggaaat atttcaagag gattaagaaa ttttcttaaa
    33121 gggataataa tttttatgaa aatggaacaa atatgaaaat aaagttatga tttttacagc
    33181 cataacctta ccaacaagca cttaattatc actcaaaaaa taaactttta tttaaagaat
    33241 gcacataaat atttccatgt tcaaaacact tctatgatat atttattaat aaatctacca
    33301 tacaaaaaac tagaggtaca ttaatcataa aaatatgatt aactgtacct ctaattatac
    33361 tcatcttttc ataaatttaa tcactatgca tcaacatatc aacatattga ttaaacttat
    33421 cttatataac aatatcttag ctactaatat aatatatatt agtcttgaat aatactttct
    33481 cttgattcaa tttcttttga aatactagct ataaattcat ctaatttaat actacctatt
    33541 tcacctttat ctcttgatct aacagaaaca ttattatcag ctacttcttt ttcacctact
    33601 attaacatgt atggcacttt ttcaagctga gcttctctta tcttaaatcc aattttttca
    33661 gctctatcat ctaattcaac tcttataccc ttatcaaata actctttctt aacttcattt
    33721 gcataatcca taaatttatc agatatagga agtatcttaa cttgagttgg agataaccaa
    33781 actgggaatt taccagcata atgctctatt aatataccta taaatctttc tatactacca
    33841 aaagcaaccc tatgaatcat aactggtcta tgcttttcac catcttgacc aatataagta
    33901 ttatcaaatt gtcttggaag ctgcatatct aattggatag taccacattg ccaagttctt
    33961 cctaaacaat cttttagatg gaagtctatc ttaggaccat agaatgctcc atcaccctca
    34021 ttaatagtat atggtagacc taactcttct aaagcttctc ttaatccatt ttctgctgct
    34081 tcccactctt cgtcgcttcc catagagttc tctggtcttg tagataattc taaattatat
    34141 tcaaatccaa aagttttgta tataccatct attaagttag ctactccttt tatttcgtcc
    34201 ttaatttgct ctggtaacat gaatatatgt gaatcgtctt gagtaaatgc tctaactctc
    34261 attaatcctt gtaatgcacc agataactca tgtctatgaa ctctaccaag ctctgcaact
    34321 ctcattggga aatctctata tgaatgtagt tgagagttat agtaaattaa tccaccagga
    34381 cagttcatag gttttatagc ataatcctca tcatctattt taactgtata catattttct
    34441 ttgtaatgat accagtgtcc tgaagtctcc cataattttc tatttaatat gattggagat
    34501 tctatctcaa tatatccagc ttttctgtgt atttctctcc agaattttaa taattcattt
    34561 ttaagttcca taccttttgg taaaaacata gggaatcctg gaccttcttc aggtatcata
    34621 aataatccta attctttacc taattttctg tggtctctct ttttagcttc ttctagtaaa
    34681 tgtaagtact cttctaagtc tttgtttttc tcaaaagaag ttccatatat tctttgaagc
    34741 atcttattat tttcgtcacc acgccaatat gcacctgcta cactttgtaa tttaacagct
    34801 tttacctttt tagtagatgg taaatgtggt cctctacata aatcagtaaa atcaccttgc
    34861 ttgtagaaag atattatttc actttcaggt aaatcagaaa taagttctac cttatagtct
    34921 tctccttgtt ctttcataag ctctaaagct tcatttctag gaagttcaaa tctttctatt
    34981 tttaaatctt ctttagctat ttttttcatt tcagcttcta ttttctctag gtcctctgga
    35041 actaatctat ggtctaaatc tatatcatag tagaatccat tttctatact tggtcctata
    35101 gcaagctttg cttctgggta aagtcttttt atagcttgag ctaatatatg cgctgatgta
    35161 tgtctaaaaa cttccttacc ttctttatct tcaaacttaa ataaattcaa gtcacaatca
    35221 gtatctataa tgtggtccag acctacaacc tctccgttca cagacgctgc taccacattt
    35281 ctagctaatc cttcactaat ggatttagct acatccataa cagaaatagc attttcaaat
    35341 tcttttattg agccatcttt taaagcaact ttaatcattg ttttttcctc cttattgaaa
    35401 taatttttag attttttgta ataaaaaatc gccccaaata tgtttgggac gatattaatt
    35461 cgcggttcca cccaagttgg cgtatacaag tatatacaac cctcttgatg actataaggt
    35521 cgtcacccga gcactttcac gtatagtata aatacaaata ctgctaataa gctcagctcc
    35581 aaggtagttt tcaaatagac ctattacatg ggctctcagc catagaccca aattctctga
    35641 gaatggtttc tactctactc ttcctcttca acactatgat ttttaatata ttttcattat
    35701 aacagatagt tatacatcaa tcaacattaa tgtaatatat taattaccca ttatttttca
    35761 tctcaatcag ctgtaaacca atattcttat atttttatat taaattaatc tcttgattta
    35821 tagttatatt ataatatttt cataaattta aaatttttaa aacgtatcca catgcatgat
    35881 agatatgact agataaatac taaaactaat ttttattaaa actaacttct aatttttgta
    35941 ctctttttag gttttgtata cttaaataca atcaatactt aatatggtta ataagtagta
    36001 cagtaaatac ttaaatacta ttaataagta acacaatcaa ataaataaat acaattaata
    36061 tctaaatgct attaataagt aattcactca aataggtaaa tacaattaat atctaaatac
    36121 tattaataag taattcactc aaataggtaa atacaattaa tatctaaatg ctattaataa
    36181 gtaatttact caaataggta aatacaatta atatctaaat gttattaata agtaattcac
    36241 tcaaataggt aaatataatt agtacttaaa taaatgctac ttctcatata tttaaataaa
    36301 catagtaatt aacccttgag ctatacctat taaaaaccct aagacaagcc ccaaaaactc
    36361 tatatgtttt aattctttct tagctattct tattattatc tcttccaatt catataaatc
    36421 tagttcatta atcttatctt cgaccatttt ttgtatatct atacgttcat ttgctttatt
    36481 tattatattt ttactcaatt catctatact ttgcttaact tcagactcaa ttatctctcc
    36541 tagataatct tgtatcatgt tttttatacc actcgggata aatgaaactt tctcatgtat
    36601 tataattttt acccttgctt ttatgtatct tacaacttct tccttatctt cgtcagtaat
    36661 gatatttgca agtatttcgt ccatagaaag aaattcttct tgaattattt ctcctacatt
    36721 tgctgctatt tctgctcttc tctttggtat aagacctact atttctatat ttaaaatagg
    36781 tattttaata ggctctattg gtctaaatat cagtcttata gcaactacat tcgtaacata
    36841 acctataaat ccaccaataa cagctaatat cagtatccta attaaattat ccattataaa
    36901 attactcctt atcaattgta tatttgccag ctatattgca ttaatcaagt agatattctt
    36961 tatacttaat aactctagtt atactatagc tttatataca attataagtc ttttgtgtcg
    37021 atttaaaaag aattttttta attttatatg gatagctttt atatgcttag attctagttt
    37081 tccataatta tactaacttt attttcaaaa attgcttcta cagtatctat aatttccttt
    37141 gagcaattat tatttaacaa atccaatatt tctatttttt tgggacatag agttaataag
    37201 gtacttatta aaaagtcctc ataatttaaa ttttctctta ttaccatatt tataatttct
    37261 tcatcatcta tactgtctat cttatttcca tttttatcgt ataaaacaaa tgtattatct
    37321 tccattatat gaactttaag caaatcaatc ttttcttctt gagtatctat aaagtatttt
    37381 aaaactctta taaattcatc ttggtctttc tttattaaat actcctcaac tgcaatatca
    37441 cctatagcag aaatatattt cataaattct ctcattctaa atctaataaa accttctaca
    37501 tttataaaat cattttcttc tatataattt ctcaccctag taaatactgt ttctctcata
    37561 aaaatctctt ttttagcaaa tatgttcagt gaatatatgt atatattatt tttatcttca
    37621 ggatatgtac gcccatagca ttttagaatg tattctttca aaagtttctc tttcattata
    37681 cttattatca tactagttat ttccgttgat atctcatcaa tatttaaagc tctttgttca
    37741 gctttagtac cattaagtat ttttttattt aacacttctt gctttgcaga atctatcact
    37801 acttctacaa tgtcattcgt atatattaat ctatcgttta cattattatt cctcaaaaat
    37861 ttcatggaag aaatattatc cttctcaacc aaagttatcg ctcctttctt gtcatgagag
    37921 gaactataga acctatatct agtaaatttt cacagctaag tgtaactatc tccttgtttt
    37981 tactttctac aaaacttttt atacgttcat agtcaggatg ttttttaaca tctccacaaa
    38041 aagctagttt atccttagaa atcaaccctg tacatccacc tataaatcca taattcatct
    38101 caaataaatt tatgtgacct ttttctatca ataaacactc tatttctgta ttcttcatac
    38161 ttttccaaat acctttatct gatgttatta tagacgttct atctactata cagattgagc
    38221 atttagaata gccctgctct atatttatct ttttaagttt attattttca atataatcta
    38281 atattgcttt gtcagtatac ttaaaattgt gtatagcata gtcaccaact atcgcaatat
    38341 tgtaaggtat atcataaggg tatctattta ataaattagc ttctccctta attatattaa
    38401 atttatatct acttaataac tctttgtatt gattatatac attcggcgca acaattatat
    38461 ctccttttcc taaattacaa atacatatat ccgggtgata ttttatgctt tcatataatt
    38521 ctttacattc tattgttttt attatctcta tatttcttaa ttttaattca ttttccatta
    38581 gataactaat tcttttgtcc accaaagcta gacacaaatc gtcatctagt ataaatggtt
    38641 ctcttgtaaa ttccattttt tactcctttt tctttttttt gataaatttt ttatgtgaat
    38701 ataaataaag tgtgtagcag aatttttctg cccacacact tattgttata attttatata
    38761 gttattctaa gcttaattag tatagctttg tacagttggt tcaaatttaa taaatatatc
    38821 tttttatcac taatctaaac ttaagcagta tattccgtac agttagcaca aatttaataa
    38881 atatatcttt ttattgctaa tctaaactca atcaatatat tttgtacagt tagactaaat
    38941 ttaataaata tatcctttta tcaccaatct aaacttaagc agtatattcc atactgttaa
    39001 cacaaattta ataaatatat ctttttatca ctaatctaaa cttaatcaat atattttgta
    39061 cagttagcac aaatttaata aatatatctt tttattgcta atctaaactt aagcaatata
    39121 tttttataat cttctacatc aataattaat atgtatcttt cactttgtta tactcttttt
    39181 ttatgtattc caaaacatct ggtggtatat ttctactgct ctttgaagtc aagccaagtt
    39241 ccccatcttt tattttaaat tccattactt tacttccctt aaaaccatct tttgcaacgt
    39301 tctttatcag ttcatataca ggttgttcta catcttttat aattgaactt attacattat
    39361 ctggagccat atcgtattgg tctttattaa tagctataac tttaccacca ttttctcttg
    39421 ctacctgaat agctctttta ctatcatctt ctgtagctga aaatacaaca tctctatcag
    39481 aatctctcat ttcctttgca atagttctag ctgattcagg gttttcaaat atatttgaat
    39541 acttaactag taactcagca tctttatttg aagttttaag cccctttcta aatccagatt
    39601 catacttatc tctactagaa ccctcaactc ctcctataaa accgactttc ccagtatcag
    39661 tcattttacc tgcaataagt cctgctaaat atccagtaac attatcttga aatgatacag
    39721 aaattacatt agctggctga actttataag tatagtcaac tattgcaaat tgctgtttgg
    39781 gatatttagt agcagcttct ttaattggct ctgcaaatct ggctccaact gctattataa
    39841 aatctggttc atacttatgc agtttttcta tactctcttt aaaactttta gaagtctttg
    39901 gtttttcaag ttttatccta acatcaaaat cttcgtcagc cctttttaag gctgatagta
    39961 cattgttatt atatgattcg ttatttaagt tttcggtatc taacaatact ccaatagttt
    40021 ttcttacata tgaatcatct tctgtgtcat cttctttatt cttactttta ctatttgatt
    40081 tatccttttc tgctgaagtt agcaaacttt tagactcact ctgtttcgat ttagcactat
    40141 ctatattaga attattctta tttactttat caaacccaaa atcaaaatta catatagcta
    40201 atataaaaat tgtaaaaact actacaaagc aagccatcaa tatccttttt attttcacaa
    40261 aattcactcc ctgatttaga taggtctgac ctacctctgc atatgtcttt ctatatatgt
    40321 ctattataac atccaattca cctcataact aaactcataa gtattcttgg atattatagt
    40381 agattattta ttgttcttat taacatattc taacacatct ggaggaatat tttgagaact
    40441 attttgggca agtccagtac ttccagactt aactgtgttt tctataacct ttccgccttt
    40501 ataatttcct tttacaaaac tttgtatcag attataagta ggattctcaa aatcttttac
    40561 aatagaactt ataacatttt ctggagctaa ctcatgttgg tctttattcg ttgctataac
    40621 ttttttattt tttgccctta ctgcatctat tacagctttt gaatcatctt cagtagtaga
    40681 aaaaataata tccactccat tatccatcat ttttttagct atagattcta ctgatttgct
    40741 atctttaaaa acatctgcat actcaactga aatatccttt atactactat tagaaaattt
    40801 aacaccctct ctaaaacctg attcaaattt atctctacta gaactctttg ttcctcccat
    40861 aaaaccaacc ttatcgcttt cagtcatttt tccagcaatt aatccagcta ggtatccaga
    40921 tttattatct tcataagaaa ttgaagttat attagaaggt tgcttgtcat actcatagtc
    40981 tataattgca aattgttgct ttggatattt cttggctacc atctccaatg gttttgcaaa
    41041 tctagctcct acagctataa ttaaatcgta attgtcatta cataaaatat ctatactatt
    41101 agaaaaagtt gaggaatcat ctgattccac tttgtttgta tctatattaa gtttcttttg
    41161 agcattgttt aatgctaata aagctgaatt attcatagct tcattatttg ttccttcaat
    41221 atctagtatc attgatacag atttttttga attactttta tcgcttatat cacttttatt
    41281 atctttgcta gagctaggat tattacttgg gttattagca cacccaacca acattccagc
    41341 tatcattgct acagttaaca tcaatatcaa tattcttttg aaacgcatta aatttcactc
    41401 ctcatacatt tacgatattt ttatatccta tttactttta catcctattt ataatttttt
    41461 tatatacaat ttacaagtac attttgaaat ttttttaata aatcttacta taaaaaagtg
    41521 tgcaatagat tcttatctat ttacacactt ccctacaaac taaatctaat atatcaacac
    41581 ttaatttcat ccaaaataaa tccaatttaa catctcaaca attaatattc tatcctaatt
    41641 taataaaaaa ataaataatg tcatccaaaa atatattatt tattttttaa gcatatgata
    41701 ccagtaacac caggaccagc atgtgcacct atacacacac caatttggaa aaatctaatt
    41761 tctttaggtc ttaattcatc ttgcataacc ttagataatt gttctttttc cttaaaatca
    41821 tcactatatc ctatatacac aatttggtct gataaatcat caccacaatt tgattttatc
    41881 aattccatca tcttagaaat tacattcttc tttcctctta cttgagatat ttgcgaaact
    41941 aatccatctc ttatttcaag aatcggtttt atatttaata tacttcctat tgctgcctta
    42001 gtagatgata ttctacctcc cttttgtaaa tattccaatg tatctactga aaatataaca
    42061 aaagccttct cttttaattc atccaaaaca ggcaatattt cagcaacaga ctttccttca
    42121 cttgcaagtt ctcctgcttt tattacaagt aaaccagttc ccatacaaag caagttagag
    42181 tcatatgtat atattttacc atctacatca ttctttgcca ttacagcact ttgatacgta
    42241 cctgtagctg tggcagaccc tgctatataa agtatctctc tatcctcatt tgtatatttc
    42301 tcaaaaattt ccttaaattg ggcataagta gcttgagaag tttttggata tacattttct
    42361 tctctaagcc ttttataaaa ttcatctcca gatatatcaa ttctatcctt gtattctctt
    42421 tcctccagta taactgttaa tgaaactata tctatatcat atttatctaa caaatctttt
    42481 ggcacgtccg ataaactgtc acagattatc tttagatttt tcattaagta tgctcctttc
    42541 tcatttaggc ttgttgaaac tacctcatat ttgggtatcc tatttgtctt aaagcctcgt
    42601 acactacaat agcaactgaa tttgataaat ttaatgacct agctttttca acatccaaca
    42661 taggcactct aatacaagta tccatatttg ctttcaacaa aggttctggt aatccctttg
    42721 tttctttccc aaatactata aaacaatttt cttcatattt cacatctgaa tgtgactgtt
    42781 tagcctttgt tgtagaaaaa aagtatttac tatttggata cttttcttgt aattcttcaa
    42841 agctatcgta atattgtata tcagctatat cccaatagtc aagcccacat ctttttaggt
    42901 gtttatcatc caatgaaaaa cccagtggtt ttactaaatg taaagttgaa cctgttgctg
    42961 cacaggttct tattatattt cctgtatttt gaggtatttc tggttctact aatactatat
    43021 ttaatgacat tttaatcctc cctaagtatc gcttttattt atcaaatttt attttataaa
    43081 cagaataaca ataatattat actattatat aaaataatgt taataataat ttttatttca
    43141 tgtatataat agttttttat ctaacatttt cacaagtatt attatatcag aaaatccctc
    43201 ttgtacaact tactttctaa aagttatttc gtttcattaa gttctttata ataattacaa
    43261 tcttctttta ttgggcaact tgcacattct ggatttctag ctttacacat tcttcttcca
    43321 tgaaaaatta atacatgatg tgagtgtgac catctttctt ttggtatagc ttccataagt
    43381 gcaaattctg ttttttgagg atttggctcg tccactattc ctattctatt gctaactcta
    43441 aatacatgag tatctacagc tattgctgga tgattaaaag cgttactaag tacaacccct
    43501 gccgtttttc ttccaacacc aggtaatttt ataagctttt ctaagctatc aggtacttca
    43561 ccatcatata attcacatag ctgttcagat gtatccttta ttttttgaga cttgcttttg
    43621 taaagaccac aactctttat ctctttacta atttcttcaa tgctcaaatt agcaaagtct
    43681 ctagctgtgt tgtacttttt aaacaactct gaagtaactt tattcactct tacatcagta
    43741 cattgtgctg ataaaatagt tgctattaaa agttcaaagg ctgtcccata atttaactca
    43801 catttagcat ctggatacaa tttttctaac tcgtctaaaa tcttatttac gtctttttca
    43861 tttgctgact catttttaat tttagactta cttttagttt ctttacttgt tttttgtgta
    43921 gccttattag aactactctt ctttgttttt ttctccgttt cacctttttt agtacttttt
    43981 ttacttactt tgatactttt tttatcttct tcaatatcca taaaattctc tatatctttc
    44041 tcatcaatta tctcatcttt tttaccaatc attttatcta ttcctttttc atttatctct
    44101 tccttctcaa ttatatcttt cttattcatt ccttttttat ttatctcttc cttctcaatt
    44161 atatctttct tattcattcc ttttttattt atctcttcct tctcaattat atctttctta
    44221 tctattcctt ttttatttat ctcttccttc tcaattatat ctttcttatc tattcctttt
    44281 ttatttatct cttccttctc aattatattt ttcttatcca ttcctttttt atttatctct
    44341 tcttccaaaa ttacatcttt ttcatttatc tcttttagat ttacattttt cataattatc
    44401 ccccttcaaa ataccaattt ataaaacgct atttataaat agtttaatca tatcaacaaa
    44461 aaaataaaca tcaatatata aaacatacaa aataagaatt taatttatat atatttacaa
    44521 aaaaagcaaa aacctattaa agttcttgct ttttattata cataaatacc cattaaattc
    44581 tataataaac ttattctttt gacacagttt gtatcttgct gaaagatatt aatttttctt
    44641 ttaccaattt ctttatttct tcaaatttaa catctgtcaa tatctctata gcctcttcta
    44701 ctctttcaac agtatatatc ttaaattttc catctcgcac tgcatcatta acttcatctg
    44761 ataaaacgag atttctttga ttttttctag gaattatgac gccttgctca ccatttaacc
    44821 ctttagtttt acatatagaa taaaatcctt ctatcttttc acttatacca ccaactactt
    44881 gtatatcacc cttttgattt atagaacctg taacagcaat attttgttta attgatactc
    44941 cactaagaga tgataatagt acatataatt ctgcagaaga tgcactatct ccatctattc
    45001 caccataatt ttgttcaaaa caaacatatg catttagtga caatagtaaa tcctgtgcaa
    45061 aattctcaga aagatagcca cctaatataa gtactccttt gttatgtata gagccactca
    45121 tatttacttc tctttctata tttactatgc ctttacttcc tgggctagtg gtcgctgtaa
    45181 tccttgaagc tctaccaaaa gagtattctc ctgtacttaa gactgacaaa ccatttatca
    45241 ctcctacttt tcttccctct gtttctatta gagtaaatcc attttcaatt gattcatcca
    45301 tatgtgtttc cactctattg attctttttc tcttttcact tattgctttt ttaacatcac
    45361 actgctctgt atactccgaa tttctaaact ctgcataagc acttccttct attacaactt
    45421 ccattatttt attaaactta gttgataatt tttctaaatc accagataat ctagtgctaa
    45481 atttaataac ctcttcaact gctgatttag taaaatgcct taaattattc ttatcacatt
    45541 ggtatgctat aaatcttgct attccttctt cattatcttc atttttatcc atttcactat
    45601 caaagtctac aaatacttta aaatattttt caaaatcttc atcatatcta tataaaatat
    45661 catatatata gtggcttcca atcagtacta atttaacatc caatggcata ttttctggtt
    45721 taattgctgt ttgtgtttcc aatattactt ttttagtctg caaagtcttt ttaagaattt
    45781 cccaagacat tgtatatttt agtaattggt ctgcataaag tactaaataa ccaccattag
    45841 ccctatgaaa tgctcctgat aatagttttg tgaaatcagt ctttatattt ccatttgcat
    45901 aatcatactc tgcctttcca aatagatttg ctggacttgg gtttatctct actacaacag
    45961 gtgctgattc tttattcttt gagcttccat tgtctacaaa taggttaatt ttatatttaa
    46021 taaaatgctc tttatcatac ttatctttta actcctcttc atctaaatag aataaataca
    46081 tatattctat tatatctttc tttatatttt ccagataagt ttgaatctta tcataatttt
    46141 catatttttc acacaatctc ttgatatgag gttctactac aagtttagct atctcttctt
    46201 caagctctaa cactgctttt tcagctattt cttctaagtt tctaatttta tatacgacct
    46261 gtatcgccat attttctagt tctcttttag ctttgtaaaa ctcttcatca gactcatcac
    46321 tttcatcttc ctcttctttc aaagggataa aaactattcc cattttactc tgttttaatt
    46381 taaatccttt ttcttctcca tattttttaa tttgcttcaa aagcatatct ttttctattt
    46441 catattcatc cagaagttta tttttttcta tttcaaaatt ttcactttca aacgcatttt
    46501 taaaatcttc taaaagactt tcaattaatt tctccatatc tttcttaagt tctcttccaa
    46561 accccttttc taattcaact ataataggct ctctagggtt ttcaaaatta tatatataac
    46621 accaatcttt atgcgtattt tttttggatg catactcatt taaaaccttt aaggcataag
    46681 tacttttacc agttccaggt tcaccagcta tatatatgtt gtacgctgga ttatttattt
    46741 tcaaccctaa ttccatagct tctacagctc tttcttgacc caatatataa tctagtggat
    46801 ttatttcaga tgtattatta tatttcaata ttcccccacc tccccatatt taactttaat
    46861 gatataatat gacttttaca caacaagtgt taaagtaaat acacattaaa gtatatgaaa
    46921 cagactctta ttattagtca tcatacttat ctaaaattat ttccatattt ctctttatta
    46981 tatttcttcc tctccagcta aaagctctat ctccatattt ccttttaaat tctttatttg
    47041 aaatattttg tatctcatca taattcaaat aatctattat attttcttta aattccaaaa
    47101 tatgagttgt tggtatttca acattatgtg gacatacttc ttgacaaata tcgcatccaa
    47161 ataccttttt gccattcttt aaaacaactt tttctttctc tgacaaatct cctttttttt
    47221 gagttatata tgataaacat tttttggggt tcatatcata atttcccaat atagcatttc
    47281 ccggacaata ttttacacac tttccacatt taaaacaact tttttctagt ggtttatctt
    47341 cttcaaattt ataattattt actatatacc ctataaatac gtaagaacca tattcatcag
    47401 ttatgatatt attatttatt ccaaaatatc ctattcctga taaataagct aaatacctgt
    47461 caactaatgg tccattatca gcaaataact tgtatttaaa atctgttact gttttagaaa
    47521 tataatcaca aatttgttgt aaaaagtcct ttactacaat gtgataatcc tttccatgac
    47581 aatattttga taaatttgaa tttttattct tttcttgtct atttatatga tatggaaatg
    47641 cacagactat tatagagtta gcatccttca ttatatgtct tgggttaatt ctgttctcaa
    47701 ttattggttc ttccatacca gttaaataac ctttttgttg tctgtcctta agtatctttt
    47761 ctaaattatc atacttatct acccctgcta ctcctacaca gtttaatcct attaaattac
    47821 aaaatgcttt taattcctta ttatccataa aattattcct ttttaatcta attgactttt
    47881 taaatttatt taattttttt agtcttttta accttttcta gctactaact cttttaaata
    47941 cttaatcttt ttagctattc aattttctta cctacttaaa tcttttagat acttcgtctt
    48001 tttacctatt taatttttta cctactaacg cttttagata cttaatcttt ttatctattt
    48061 agttttttac ctactaactc ttttagatac ttcatctttt ttatttacta actcttttag
    48121 atacttcgtc tttttcattt acttatttaa cttttttatc tacttaactc ctttaaataa
    48181 ttagtctttt tatctattta attattttac ctactaactc ttttgaatac ttagtctttt
    48241 ttatttattt aattttttta tctactaacg cttttagata cttaatcttt ttatctattt
    48301 aattttttta tctactaact cctttatata cttagccttt ttcatttact tatttaacta
    48361 ctaactcttt tagatactta gcctttttca tttacttatt taactttttt acctacttaa
    48421 ctcttttaga tacttagcct ttttaatcta ttcaaccttt tttacccact taaccttctt
    48481 accttttaat ataaactcta aaacttcaaa tatcattagt tatattttga cattctttct
    48541 atagttaagc aaaaagattg attttttctt ataattaata tcccatttac attgccattt
    48601 attaaatctt tacttgactt atatggattt ctttttactc tctttactaa actatactta
    48661 ttaatattat gaaggtctta taatagacta atatgaatat gtccatcata tatcaaattt
    48721 taaaatttgt aagcaaaata cttatcttat attactacat ctaaagtgga aaattttaca
    48781 aaaaagctct gtaaaaacac tttaaataac aatttgcttt taaatcatat acagattata
    48841 ataaatactg tataaggatg gtgaaaaatt tgattaaaat aacaattcca ggtagaccta
    48901 ttagtaaatc taattttaag cttcataaca taaatggtca agcatggatg ccttcaaagg
    48961 gaaaatattc taagtatctt gcatacgaaa acatgattgc aggttttata aaccaacagt
    49021 atcaagggga aactgtcgaa gaaaatctaa taacagtctt gaaattattc ttcccaaata
    49081 agagaatggg ggatttacat aattatccaa aaagtatttg tgatggtatt gaaaaaagtg
    49141 gaataataaa aaatgataaa caacttaagc cagtactttt atttgatttt atagataaag
    49201 ataaccctag ggttgaaatt gaactttatc cagtatctaa atacgatata tcctataata
    49261 tttttgaaaa ataaagattt tatgtgttat tcgacattat attgatactc cagtatttga
    49321 aactatacta atacaacaat aataattgtg ttatgtctat actcaaacaa atgtttttaa
    49381 aaagcattaa gtaaatattt aataagtatt aaacaaatat taaatttata taatagctat
    49441 aactatgtaa atttaatatt tgtatataag accacatcta ataaaaagaa atcggagtaa
    49501 atttaataca ccgatttcaa taaataaaat ctatcctagc ttttcaacaa cagtcttaag
    49561 catttctctt ataggaagtt catatggaca tctactctcg caaagcccac agtcaataca
    49621 ctcagtaggt ttaacatcca taacctcata tttttcttta gcccactctt ttaatccata
    49681 tctagtataa taaccttcac ataaaaaact caatggtata tttattccta cagcacaagg
    49741 catacaatat tcgcatcttc tacagaattt tttacctaaa gaatttctta tttcttcaat
    49801 ttccttatta tctttttcat ctagcacaag attttcaagt acagcgacat tttgtctaac
    49861 ctgttcaaca ctctccatac ctggtataac tacatctatg tactctttag atagtatata
    49921 tttaatagcc agtgttgcat tgtctaaagc acctccagct aaaggtttca ttactattat
    49981 cccaattcct ttttcatgag cttttttaaa cacttcatct gcttgtcctt caactatatt
    50041 ataagggaat tgtatagtgt caaattttcc atcttctata gctttttcta tagtatttaa
    50101 attgtgacta gttataccaa tatgttttat cttaccttgc tcctttgcct ctaaaagggc
    50161 actataagcc attttatctt taaaaagatt atcatactcc tcttctttaa cattatggaa
    50221 ttgatataaa tctataaaat cagttttaaa attatttaaa cttatttcaa catctctctt
    50281 cattgaatca taatctctgg acatactttt agtagctaag aaaaatttat ctctttttcc
    50341 ttcaatggca attccgattg cttcctcact tattgtatac cctcttgcac tgtcaataaa
    50401 gtttattcct tgtttttcta actcatttat aactaagtta gtatcatctt gagtaatcct
    50461 ttgtattgga atgcccccaa agccaactct ctttattttc atgttagtat tgcctaaatt
    50521 tctcatatct ttccccacct aacttttaat aattttttat ataatataaa tatgtcacct
    50581 ttaattatac aacaaattat gagaatcttt gcaatgtatt tacatactat tcataatata
    50641 attatatttt atatcagtct attcataata taatcatact ttatacccag ttaatttgta
    50701 tacaattttc gttattccta tccattaatt taaattatca catttcatga ttgtatctcc
    50761 accctaatta tgttgagggt ggagtatttc acatattttt aataaaggtt tatttactag
    50821 atagtatttc ttttatcatt ttaagctctc tcttgtgacc ttcatcatca aaaggagttt
    50881 ctaagaaaaa tggtaaatgt tttagactag gatgttccat aaaatcaatt aatgctttta
    50941 atcctatctt tccttcccct ataggagcat gtctgtcttt tttgtctcca aatggcatca
    51001 tactatcatt tagatggaca gttttcaatc tttctatgcc tataacctta tcaaattctt
    51061 ccaaaacccc atctaaatca ttcactatat cataaccagc tgaaaaaata tgacatgtat
    51121 caagacacac acctattttt tctttatgct caattttgtc tattatactt tttaattgct
    51181 caaatttaaa acctatttca gttccctttc ccgacatagt ttcaagaagt atagttatat
    51241 tttcatcacc ctttatggca ttgttcaatc cttttactat tctatctatg ccaaaatcta
    51301 caccaccacc tacatgactt ccaggatgaa aacacatgta ttcaattcct aataagtcca
    51361 tccttcttat atcctcatct atcacccttg ttgcaaattc gtatacatca tcctttgtac
    51421 cacccagatt catagtatat ggtgcatgtg caagcagtgg tgcaaaatta ttttcttttc
    51481 taatttcttg aaatttaatt atatcttttt catcaaattc tttagcattt cctcctcttg
    51541 gatttctact aaaaaattga aatgtatttg caccaatata tacagctgtc tcagccgcat
    51601 tagcaaatcc ttttgctatt gaaagatgtg ttcctaattt aatcatatta atctcctttt
    51661 atttgtacta ctacttgtac tcaattttaa ttttgaacta ctccacctta actacattta
    51721 gccaacatat gaagatggag attcctattt gatagtactt tttcactaaa aattcgtaag
    51781 ctctaaggga tgttctatcc caactaatct cattcctctt ttaacatatt tctagcattg
    51841 atttaattta tattaatttt taattttaat atttacactt taattatacc cattttaatc
    51901 aatttcaaat attataatct tacatacttt gtatattatc taagcacttc ttagatagtg
    51961 tatacatctt acactataca tattatttac aaatacaata ggtataaaaa aacaaaaaaa
    52021 tagagattaa aaatcattgt tttacccata ccaaaaacta ttttttgatt attaagtaaa
    52081 ttttgatgtt caatctctaa tattatatct ttaattaatc cataattaat tctctaacta
    52141 ggacattcct cctcaagagt aggaactata accatagcta tatcatactt agaaccttca
    52201 acattgtgtt gtcttttatt taaaatttca tctatctttg acttcatagt gtcactaagt
    52261 tcaactaatt catcatgagt aagagaaata tcatgataat caactatatt ttcattttct
    52321 aaaacatctt cctctgctgc cttataaaaa acttcactca tattttcaaa ttttgatatg
    52381 tacaattctt ctttttcttc cccattgtct aaagaaaaat taagtatcct attccctata
    52441 accacatttt ttgcacttgg ataatagtac ttttccacaa tccccgactt tattttttcc
    52501 tcaactaatt ctaaaatacc aactttgtat aacattttta tatggtagtt tatttttgca
    52561 tgaggttctt ccaataattg agataattgt tttgctgaca atggcgattt gtcaaatgct
    52621 tttagaatat ctattctacg tggatgcgca atagccttta tgcactccaa atctcgtaat
    52681 accaatacct ctttcattga cccctcctaa aaaatttatt taattcatat ttctttacaa
    52741 tttaattata tattaaatta tatgttgttg tcaaaaaaat cctttcttaa tattttaaaa
    52801 aatatttaat ttgagtttat ttgacaactc ctctaaaact ttaactcctg cgacgctgtt
    52861 accttttttg tcaagcgcag gtccataaac accaatcccc atgcgtcccg gcacagaagc
    52921 cattatacca cccccaactc cagattttgc aggaatgcca actttaatag caaattcccc
    52981 agaagcatca tacattccac aagtcatcat aaatgtcttg acaatcctag aaaccatttc
    53041 actcattaaa tgctcaccat tttctatatc tactccataa tttgcaagat ttattccaat
    53101 tctcgctaaa tctacagaat ctatctcaat tgagcattgt ttaaaataaa ggtctagaac
    53161 atcttctaca ttccctctga taaatccatc acttttcaat aagtaagcca tagctctgtt
    53221 tctatctcca gtcatttttt cagacttata gacatcatag tttattccta tattatcatt
    53281 ttttgctaac tttctaaaga aactaagcat tctttcttct ttttcttcta aacaactccc
    53341 atttataagg gaagtggtta ctatagcccc tgcatttatc attggattac agggtttttt
    53401 tgtgtcatta atttcaagtt tcattattga attaaatggg tccccacttg gctccattcc
    53461 aacgtttgaa aaaacgtctt cccaatcatt atccataagt gccatagcaa gcacaattgg
    53521 ttttgaaata ctttgtatag taaactttgt gctacagttt ccagcactat aaagattatt
    53581 ttcgctatct atgatacaaa ttcctaaatc atttcttcta gcgtttttta attctggtat
    53641 gtaactagcg acttgtccat aattagtata cttcttatta gaacttataa tttcttttaa
    53701 taatgtctca tctaacgtat tcatatgcac ctcttatatt atgttatata ttctatttta
    53761 gcacaagttt atactataat aaaacaatgt taaaaaaaat tatactttaa aattattttc
    53821 tacaagaatc aattcatttt tcaaacaatt taaatagttt aaatagctta ataatttaat
    53881 aatttaacaa cctagcaatt tagtaatcta ataatccagt aatttaacaa cctaataatt
    53941 tagcaatcta ataatctaac tatctaataa tccagtaact taacaaccta gtaatttagt
    54001 aattcaacaa tctaacaatt caataattta acaatttaac aacctagtaa tctaactatc
    54061 taataatcca gtaacttaac aacctagtaa tttagtaatt caacaatcta ataattcaat
    54121 aatttaacaa cctagtaatc taactatcta aataatccag taacttaaca acctagtaat
    54181 ttagtaattc aacaacctaa taattcaata atttaacaac ctagtaatct aactatctaa
    54241 ataatccagt aacttaacaa cctagtaatt tagtaattca acaacctaat aattcaataa
    54301 tttaacaacc tagtaattta gcaatccagc aatctaataa tccagtaatt taaattttta
    54361 taacaccaaa aatttctaac ccaacacctt ttactctttt actcttttac tcttttactc
    54421 ttttactctt ttactctttt actcttttac tcttttactc ttttactctt ttactctttt
    54481 actcttttaa aaaataatca cataaattaa caaaatatta aacaaaaaag taaaatttaa
    54541 aataaaaagc ttgcttcata caaaagtata aaacaagcct ttttatatat caactcaaac
    54601 tttaaaatct gtatcaattt aattctccac tttacactta atatacttaa cataaaccaa
    54661 taacactact tgctatgcca tttaatcttc ataaaacaat ctataataca cacattaatc
    54721 aactatttta cttcctccaa taaattccct aagaattgaa atacctggta tgtcagaagt
    54781 atcgtccaat tcaacaaaat actgcaaaaa ctttagtaat ctagtagctt caatatgtgc
    54841 aggattatct tcctttatct cttccaacaa aggtttcgca aatcgtttta aaactgccaa
    54901 ttcatataca caagcagagt taaatatagc atctgcctcc tcttggtacg ggaatatatt
    54961 cttcttttct cctcttctaa ctgatgccca ttgtaaaata gtattatcag cactatatcc
    55021 tctaaaatta tagtctctaa caattcttct tatcattctc aaatcagcag tagggattcg
    55081 attatggtca tccaaattta tttgagtaag ggcacttatg tatatcttaa atttatcttc
    55141 atctggtata gatgatgtta aaataggatt tagcccatgt ataccttcta atataattgg
    55201 ctgatttgaa tctatcttta tctttttacc agtgtattct ctcttacctt ctttaaaatt
    55261 gaatcttata tcatcaattt cttcaccagc taaaagtttc tttaagtcta agttaaactt
    55321 ctctaaatct attgcataaa ttgattcaaa atcataattt ccatattcat ctaaaggagt
    55381 atgttttcta tctataaaat aatcatctaa agaaattgaa ataggattta aattatttac
    55441 tctaagatgt attgataatc tgtgagcaaa acttgttttt ccagatgaag atggagctgc
    55501 tattaaaact actctcttat tgccatcctt tatcatatcc gctatttggg ataacttctt
    55561 ttcatgcaat gcttcaaatg tccttattat atctccatat tcattgtttt ctattatttt
    55621 attaagagat actaccttgt caattcccat aagtcttgac cattcttctg cttcataata
    55681 tacacttgat agcttaggtt gaggtacaaa tttcatagga agagtcttat cttcttcact
    55741 aggtcctaaa attataacgc ctccattata aagcttaata tcaaatgatt ttatataacc
    55801 agttgatggc aacatataac cataaaaatg gtctatatag tttctacact tatatacttt
    55861 agcactatca tactctttgt atttcaaaag ctctgccttt tcatacattt cattattttc
    55921 aaagatagaa atagcttcat ttcttgtaac ttcaattttt tctataacat aatcgttgtt
    55981 tactatctct ttcatcttgt tttttatatt ttcaacatct gcttctttaa gctttctatc
    56041 tatatgaact tcacaatata gcccatctga tagtgaatgt tctattgtaa ctctgctatc
    56101 ccaaaagatt tctctacatg ccattacaaa tataaatgac atgactctaa agtaaactct
    56161 ctctccatct tcattagtag tatctaaaaa atttatctca caatccttct taactctaca
    56221 atttagctct tttagtttat tgtctacaac tgcaagtgtt atataaccct tatgctcatc
    56281 acaaaattct tttgctatat ctcccaatct gattccaggg gaattttctt ctaatgaata
    56341 ttccttatct tttccttcta tttttaagtt tatttttttc acttcaacat ctccttcctt
    56401 ttgatgaata taaattttaa ttaatgaggc atatcaacaa gataaagaga ggtatttaac
    56461 cctctcctac aatattattc aatttactta tagtatcttc aatgtcttcg taatttattt
    56521 ctaatactaa atattctgca tctaatgtta agatctcttt aatcccctct tcagataaaa
    56581 ttcctcttcc tataccaaca tgtgtatcat tgataccatc attatcactt aagtgtatca
    56641 gtcttatttt atcctttaag ttctttacat aagcatcctc atcaattaaa cagtgtccag
    56701 tatcgtaaca aaaacaaatc ttagaatttt taatcctctt aaatatatat tcaaaatcat
    56761 aagatatatt tccaatattt gaaaaatccc caccttttga ataagtattc tctatacata
    56821 catatgaatt tgtatttaat ttatctaaaa aatccacact atttcctaaa tatttgtctc
    56881 tattctttct aactctattt gtcataacat atcccaaatg aaggttaaaa taccttaaat
    56941 caaatccttt tagttcaaat tctatcttct caataaaatt tatccatgaa tttcgtatat
    57001 actctatgtt ttcgcaagta tttaattcca taggcaaatg tatccctata gataatccta
    57061 acttagaaat tctctcttta tatttacata actcactaca ttcagatata ttgtcaattc
    57121 caatctctaa atgagttatt tgctttatac tctcacaaat gtttaaagcc tcctcaatat
    57181 taaacaataa ggacgctata ccaactgcca tacaaatcac ctactcaaaa atacctatat
    57241 ctgtaaaagg aaatactctt aaaataactt ttcctttaat attttcttca tctactaatc
    57301 ccacttcttt atatctactg tctaaactaa cttctctatt gtctcccatc gcaaatactt
    57361 ttcccttagg aatcaccata tcaatatcgc cttcagtata attatcatgt atatatgaaa
    57421 cttcatttaa taacttacca tttatataaa ccttagaatc cttaattttt agatggtcac
    57481 caggaacacc tataaccctt tttacaagct cttttttcct tccattctct tgtaataaat
    57541 cagtcttaaa tatcattata tctccacatt ttggttctga taacttatat gtcatcctgt
    57601 ttgctaccaa ataatcatgt gatttaagtg ttgggtacat tgattctcca tttactaatg
    57661 ttggttttat aaaacgagtt ataataaatg caaaaaaaag tgcagtaata attattttta
    57721 tccactctac aatctcttct ttaatagttt cattcattca caaattctcc tttatagtta
    57781 tattatcttt attgataatg tctcttaaac actatctttt agataagtct actaaataag
    57841 gtgttgtctt ttttatatag acaactattg tgtatggtct ggtgatttca gctaatcagc
    57901 gattgctcca aattttatat gtttagtcaa tagttcctat cttagaaaat ggatacaatc
    57961 tgactagaac ctttcctaaa atggtatgct cgtcgaccaa tccaacctca tcgtatctac
    58021 tatctaaact tttttctcta ttatctccca ttgcaaataa ttttccttct ggaactacga
    58081 tatcaatatc tccatcagta cgattattat gtatatagga agtctcatct aacaacttat
    58141 catttacata taccttggag tcttgtattt ttacatggtc accaggaacc ccgataactc
    58201 tttttactaa atcttttttc tttccatttt cctctgttaa gtcggttttg aatactatta
    58261 tatctttgta ttttggctct cctaccttgt acgcaattct gttaactatc aaataatcac
    58321 gttcaactaa tgtaggatac attgattctc ctttgactat tgttggcact ataaaacgag
    58381 ttattgcaaa tgccaaaaca agagctatga caatcacttt tatccattct acaacttctt
    58441 ttttaactgc ttcacccact aaaatcgtct cctctgtgtt aaatattaag tcaatctaca
    58501 gcaaaataat ctaccataaa cctacaatat aaatattata cttctttttt ctaatagttt
    58561 aaaatacttt tctaagacct ttaggataat gattcttaat tacaccagaa gattcttttc
    58621 cccaacctaa aggtattcct tcaaccgaaa ccaaaaccca tcctctacta tcattagaat
    58681 ttacaacatc cccttttaaa tatttaagaa ttgattcact ctgtacactg aagttttcaa
    58741 cattttttac atcttcaact tttaagtaat gagatagtgc atgagaaggc tcaaatctat
    58801 tcttctttaa aacccctaaa tgcaaaccat atctcaatac ttttagtttt ttcgtatctg
    58861 gatatatttc aggaagtagg tacaaatttt ctcctcttaa ataaaattta ttttttttat
    58921 tactataaaa atcaaccttt aaaaatttct tttcaaactc cctataatcc tttatttctt
    58981 tatctaaatt ttttattttt aattctttga cattacattc ttcttcttct aattttttta
    59041 ttttggcaac aaaatgacct tctcccttta tcttatgagg ccataatctt tccatttcaa
    59101 taagttctgc atgtggatat tcactgataa actcatttat aacatgctca ttttcctccc
    59161 ttgaaaaagt acaagttgag taaattaaaa tgccatcctt ctttaacatt ttatatccat
    59221 ctcttataat ctctttttgg atggattgac attctactac ctttgcataa ctccaatctg
    59281 atatggcaac ctcatccttc ctaaacatac cttgcccaga acaaggtgca tctataataa
    59341 ccttatcaaa atacccatta aacgtctttc ttaagctatt agaatcggtg tttgttataa
    59401 tacaatttct cgctccaaat cgctctaaat tttcccctag agccttaatt ctactagcat
    59461 taatttcatt agaaaccaat aaacctgtat cgtttagctt agatagtata tatgtagatt
    59521 ttccaccagg agcagcacac atatcgagaa ctttttcacc ctctttaata tctgcctttg
    59581 gtattacact cattgcagaa ggctcttgca aatagtatgc tccagcctca tgcagtggat
    59641 ttctaccagg tctgtcaatt ttatcatcat aataaaaacc ttcttctgcc catggtattt
    59701 gattcaaatc aaacaactcc aaatcaaata attttttctt gtcaattttt aaagtattta
    59761 ttctaagccc agtagtctta ctttcctcat aactttttat aaaatcatca tattcatctt
    59821 ttagtatttc ttcaatatct tctaaaaatt cctttggtaa ttctgtcaaa tctataatcc
    59881 cccttcaatc tgctttactt gtgtgtcatt tattatactt taattattta tgtctttcct
    59941 ttaaatttta tttcttcttc tttttcctaa gattaccgaa aaacactttt ttagagtgat
    60001 tcatatattt ctcaagttta tcaagattta tcttccacaa aattattaca taaactataa
    60061 gtaatataat agcccatcta tattctatca tcaatatgaa atcaaaaact ccatgtaata
    60121 aaattggaat taacaccgcc ataaacaaat actcacgtct tttattttta tttccctcaa
    60181 atttatactt agaaatatag tagcccatag taattgcaaa cattacatga gctggtatag
    60241 agataactgc cctattaata ccaacttgca gtgctagatt tctactttca gaaaaaatat
    60301 aaaccatatt ttcaattgtt gcaaatccta aagctaaaaa tacagagtaa ataataccat
    60361 ctaacttttc agtaaagtgt ttttctttaa ttagggcagg aatcagtatc agagctttta
    60421 caccttcttc tacaagtcct gcaactacaa atgatacata tattagttct gaataccctt
    60481 caaatacatt aaacttcatc agtaaatttt ctaaaagtat aattataaca cttagaaaag
    60541 cacctattaa aaaaaattta attagatgga ttaggggttc tctacaatat ctatctttag
    60601 accttatcca aaacatccct atcaatatag gaattattgc taataaaaat aaatctagct
    60661 tcatagatta ttttcctttc aaaatttttg atttatttat gatttatatc atctacttat
    60721 ttttaactta ttcgtgtttt aaatacatac taaaatatac attaaattat tttaaattat
    60781 ttaaatacaa atatactcaa atactcaaaa aaatttaaat ttatatctat attatttaac
    60841 aaatttcaag ctatattcat atcttgaaat ataagggaac taaattcatt taaagaaagg
    60901 gtgatttgat gcaagatggt ttcttaacag taagcataat tgatgctact aacaatagac
    60961 ctattcaaaa tgcagtagta aacatatatt caatgtctaa tggtagccaa agctcatcaa
    61021 ctttatacca aaacctaaga agtaatgaat ctggtcaagt gactggttta gtattaccag
    61081 caccagatgt agattactct ctacaaccat ctgatgttag accttatagc cagtatatag
    61141 tggaagccat agcagatgga tatgagacag ttgtcataga aggaacacag ttgttagcta
    61201 caattgaagc aagacaagga gttcccatgt ctcctagaac aagaagtaag cgttctttct
    61261 caagacaaag tgagttgatt tttgatatag gagaacatac tctatatggt acttatcctc
    61321 ctaagattcc agaaagtaac ttaaaaccat taccacctcc tactggtttc gttgtattag
    61381 ataaccccgt agtgcctgaa tttatagtag ttcatgatgg tttgccagaa gattcatcag
    61441 ctccaaacta ttggattcca tttaaagagt acattaaaaa catagcgtca tctgaaatat
    61501 attcaacttg gcctgaacag acaatctatg caaatgtaat agctataata tcatttactt
    61561 taaatagagt ctttactgaa tggtatagaa ataaaggata taactttaca ataacttcaa
    61621 caacagcata cgaccataag tttataaata atagaaactt atttgaacca attaacgtag
    61681 ttgtagatgc tatttttaat acttttataa aaagacctcc tacatcaaga cagccactat
    61741 tagcacaata ttgtgatgga caaaaatccc aatgtcctga ccaaatgact caatggggca
    61801 gtaaagactt aggtgaccaa ggatatgact atgagagtat actaagatat ttctatggag
    61861 atgagatagt atttgaaaga gcacctatag taagtggtgt accagtgtca ttccctggta
    61921 ctacactaca agttggttct tctgggcagt atgttagaac catacaaaat cagttaaatg
    61981 ctatatctaa ttcttatcca gctgtaccaa aagttataga agatggtatc tatggaacag
    62041 atacagaaaa cgctgttaag atattccaag gaatctttgg tttacctcaa agcggagtag
    62101 tagattttaa aacatggtat gaaatatcca gagtttatgt agctacaact agaatagctt
    62161 ctttaaatcc tttaatttaa agcttgattt agaacataaa ctcaaattat tgaataaaat
    62221 tattaattta aaataaaagt ggctgttatg aactaatata taccataagt attacttata
    62281 agtattgtag tcttaacagc cattttttag ttataacttg tttttttaga atcttaaaac
    62341 tttaaatggg ggattttaag cttcttaaaa acagtgctta gcaacttaga tttctttaaa
    62401 atattatatt tatttttaag tttaataaaa tgctattcta acgaaaaacc tactttttat
    62461 ttaaaatctc acttattatt taaaacacta tccatcactt agaatattac ttcttatata
    62521 aattattatt tattataaat acaaataata ttaatttaaa aagttattcc taatttaaat
    62581 aatactacta tcttcatcag tgaacctaaa ctgcaacttt agacttatta gctaaagcca
    62641 atattagacc taaagctata gatgcaaatg cagaagcaat tactctatac tcagcaggga
    62701 ataaaaatac aattgtatga catggtatcc agaaaaatgg tatagttttt aaaacactaa
    62761 aaccaaggta agcattccag tccacaatat ttaccacatc tttaagtttt accttaatcc
    62821 cctttccaac ctcatatttt ttatctataa aacagtccat aaccttatgg aataaaaata
    62881 cagttggtga cattagtata ttcatagttg cactcttaaa tagagcattt gcaaaagcta
    62941 ttccctcaaa tggaagcata ccatccactt gtgcttgacc tacacctgat gagtagattg
    63001 acattccata tgtggtaact acacctatta ttccccaaac tattgctcta taaaatactc
    63061 ctactggtat tttccaatcc ttatacaaaa ttctaacacc aagtaaatct cccattgtag
    63121 ctaatacagc aaactttaaa aaacctccaa tatatggatg tgcacctgtt gcttccataa
    63181 atacttctct actacttggt attgctaaga cagcaataat acaaataaga actccactcc
    63241 atataaaatc gccttttttc atatttataa atactattta atatataaat agttctcctt
    63301 tctattaaag atttatttaa tttacaatct atctacaatt atttattaat cacttattat
    63361 tagatattca ttttccatat ttaaatttat tctatccctt tatctattta ttttcttact
    63421 actctatcca ccattatcta tatatttatt ttacgattac tctttcaccc taacccttta
    63481 actatctatt ttttcttact attcttatcc acatcatcca tatatttatt ttacgattac
    63541 tctttcactc taacccttta actatctatt ttttctgata ttcttatcca ccatcatcca
    63601 tatatttatt ttacgattac tctttcaccc taacccttta actatctatt tttttctggt
    63661 attcttatct actattatct gtatatttat tttatgatta ctcttttaac ctacccccta
    63721 tactttatag taatatgttt ttaacctttt tcattattcc caatatgctt tataactaca
    63781 aatactctcc ccccttaaaa ataataataa aattaatcaa taaatttata atcatattat
    63841 tactctatgt attaagcaat tactatgcca ataaactttg atttttttta acaaatctta
    63901 aaaatcctaa aatgctaatt ttctttaact tttaatgaat ctaatagata acatttaatt
    63961 ttcgttatat ttttcagaat atttctatta ttatttttaa gaaaaaaaaa taatgttaac
    64021 atttcttaac atacattaaa aaatgttaac attataaatt gggtttaata cttttacttt
    64081 gactcgattt acttttattc tacttcttac tttattttta acttagactt tattttttta
    64141 ttacttattt gagtcttatt tattttattc tcactccata tgttcaatta catttgtcta
    64201 aattctttga tacttttatt acataatttt aacaagctta agtgttattt gggtagtgca
    64261 gttgataatt atttaaataa tcatcaactg catgtttata tcattacagt agcttaatgt
    64321 atttaatcat acttacttag gattttgaaa tatcttagag attatattta acattagtca
    64381 attgctgcat aattgtaagc aattgaaatt tgagacccat cttcattttc tatagtgata
    64441 ggcttcataa tttttaatcc ttcagttttt atcttttcta attcttgttc cattttctta
    64501 attgtttcct caaggtcttt ttgacttaca tctttgactg cattagggtc tttagcatag
    64561 tcttttaatt cttgaatatg tttagcatac tcttcataag tataatgctc aacaccatac
    64621 ttttccaatt cagtagggtc agttattcct gattttatta gagattcaaa tttaggtaaa
    64681 gcaatattag atgaatcatt tccatttgca aatactgctc cagttcctcc tagtaccatt
    64741 gcagatacca tcattgcact tataagggat ttttttattt tcataaccaa tcttcctttc
    64801 ttagagattt atttgggtag tgtagtttaa aatgactatt gcaatagtta tcaactacac
    64861 tcttagacta tcacagtagt catgtttatg tcaagccttt ttaaaaaact tttcaataaa
    64921 aaatactatc tcaaagcaaa attaattatt ttgagatagt attttaattc taaatctttt
    64981 atattactaa gatttatggt tattctatcc atgttctata ttgttcttta ttaactgcta
    65041 acaaattccc ttttcttaat atgacaaagc gattatcatt atagccactt cgctcaattg
    65101 aaacttctcc tgaatcagta taaagtacat ccttactatt actagattta tttacatacg
    65161 tttcttcact attctcagaa ttagttactt tgctcataga tgattcttca tgctctctaa
    65221 attcaattac agatactttt gccgtactaa aatgagtctc tccatcactt ttagctttac
    65281 taacaagaat atcagattct actttgggag aatataaatc agttgattta ctacttattg
    65341 aaaatccaat tttatcactt tgttcatttt ttgttaaacc aaaagattca acctcattaa
    65401 tctctttatt ttctgttgca aaaacaagac ctgtcccaca aactaataca gttgaaacta
    65461 aaaaagtaac ataagttgat tttttaaatt tcataatatt aactattctc ttttctattt
    65521 ttgtctttcc aaatccacta catattgtca ttgaaaatgg attattctcc tctgctagac
    65581 ttattagtgt ggttgcataa tcagccctat attcttcacc aagtatactc ataacctttt
    65641 catcacaact aaattctatg tctttattta gtaaaaaaaa catcacccaa actaagggat
    65701 taaaccaatg gacaacaaga gctacaagca taaataactt taacagatta tcaaagctat
    65761 taatatgaac catttcatga gttaaaacaa agtctaaagt ttgattatta gcataattca
    65821 tttgctttgg caaaataatt cgtggtttta aaataccaga tgtaagtggt gtcctagtaa
    65881 attcagatat gcaaacaata aatcttctaa aacggctatt cttacacatc cattttttaa
    65941 tgaactcatg attttttata tgaattgaag ttttaaaaag attaattatt ttaaaatatc
    66001 taaagcataa aagtatgcta aacataatag taactataaa agacaaaatg cccaacattt
    66061 ccaacatcat aatattttca atattagaca ttatttcaaa ttcgtcagaa ttgtttttac
    66121 ctgtagagtc actagctttc ttaagagtat aattttctgt tgatgtatta cccaattcca
    66181 catcaaaagt cgattcaatt atactataaa tactaaaacc agaatttaaa cttactggta
    66241 ttagaagttt aaataaaaca atcaaccaca ataatacaaa taccttttta ggtaattttt
    66301 taaataaaca tgctcttata aaaataacta ttaaaagtaa tactccagaa gtaaaactca
    66361 tttctaacaa tttaatgaac ataaatctta cctcacttta atttttcaac aatttgttta
    66421 agttttgtaa tctcatcact tgaaagattt tctttattaa taaaagctga aagaaatttt
    66481 tctgaagacc ctccaaacat tttattaatt aaagtttctg tttcctgttt ttgtacttcc
    66541 tctttgctta ttaaagcttt acaaacaaaa ttcggctcaa ttctctctat tgcacctttt
    66601 gacactaatt tttttataac ggtatacgta gtgtttctat tccatcctgt ttcttctttt
    66661 aaaattttta ctaactctcc agccttgctt tctcctctct cccatagaac ttccattact
    66721 ttaagttctg aatcaaataa ttttatctcc atataaaatc gctcctcaaa tatagttatc
    66781 acaatagtca ttactataat aaaaaactat catagtagtc tatactatgt caatcattta
    66841 ttttttaata ataaaaactg tctttttaaa aaattcttat aaaagacagt tttatcaatg
    66901 ttatacttta atgtttaatt aaagccatat tttatttaaa tatataacta tctatcttag
    66961 tacatagtat aagatttttc tttatctaat agtatatcct ctacatctgg gttttctttt
    67021 actaattgtc tataaaaatt acaattagta acacccacat atggaattag ccatagtaga
    67081 cctattccaa gagtagctat tgaaagtata taccatccta taaagctaaa gtttagtaca
    67141 aataatttaa gtacatttcc tttcatcata tctaaactag cacccattga tttaaataca
    67201 cccatattat ccttgtcttc acaaattaag aaagtagctt gagaaacata taatagcaat
    67261 atataaactg gtaacataag aacaagtatt ataagaacta gagttattcc agtagaaata
    67321 atagtcccta ttccaacatt atcacttgat aaatattcaa ttgctccact agtaagtaaa
    67381 actccaaatg ataaaaacgc tcctataatt gtgattataa aagaataaat atacacaata
    67441 attgattcaa ataaataaaa accaaaactt cttaaataaa ttctcccact tacaaagata
    67501 tctcctatct tgactttttc atctttagta attttcaaga acatacatgt aaatcctgct
    67561 gaaacgcaaa aagctattac agccactaca atagtagtca atggttcaaa aggtaatcct
    67621 acaattgata ttaatactat caatgcaata tatactgcca tagaaattgc acatatcccc
    67681 cagtttccag ataactgagc tttagatact cgttttaatt cttgccttga taccataaaa
    67741 aacacccctt tcattttata aaaaaacttt taaaaatata aataatcttt taacgtataa
    67801 tattaatata tcatattttc gactatataa gatacaatta ttcaccatgt tttatcaaga
    67861 tatgccataa ttgtattact agttttatat agtcaacatt accaaataca tcaaataaat
    67921 ttgattaatt attcaacaag taataaaata atttctatta attatacttt atttagtaaa
    67981 caaattattt aataaaaaaa ttacctaata cagtaaatta attggtaaga taaattattt
    68041 attattagta aagtaaatta tttactattt atcaagataa attatttata aaataaatca
    68101 tttataaaat ataatttata ctttgaaaat aaaataaact atcttccaaa cattttatta
    68161 tatgcttaaa agatagtttt gtgtctttaa aataaattaa attgtatata ttccttcaca
    68221 taacttttgt atattactag gtggttgcca tttaccatct tttttagtat atgtaatcat
    68281 agttgtaact tccttagttg gtttcttatt gtaaaggtct ataatcattt ttgtcatatc
    68341 atcttgaact tctttttctt ttttatcgta attcttttca tcagttacat aagattttac
    68401 taaagtgttc gcttcactca ttactttact agtatctaaa gctttactta caactttcaa
    68461 agttatctta tccttactag aagattccac tgttactgtc ttttcaacac cttgaattaa
    68521 tttaacaatt gtttcgtata tcttttcagc attttcttta ccataaagag gtgtcaattg
    68581 agcaatcatt gaaaccttgt ccttgctgtt ataagtttga atctgtttat attcagcttc
    68641 tgttaatgca tcagaaattc ctttttcatc atacttatac atttctaatg cagctaaatt
    68701 agcttcaaaa ttcgacttta ctttttcttc tgcattagaa caccctatag ttagaactaa
    68761 aactagagcc ataatcgtag ataatattaa cttttttacc attttcatac aaacatcctc
    68821 cctcaattaa aataataaaa aatttattta tcaacattat aacataaatt tgtctaacta
    68881 tagaattatt ttgaatattt taccacttcc agtctattcc aataccgttt tcttttgctt
    68941 tatcgtatat tctttttgct gttacgacat cttgtacacc tatcccaaca gttttaaata
    69001 caattatctc atcatcatct tctcttccag gaatagttcc gtttataaca tttcctaaat
    69061 caccactaaa atcatcttta cttatcttac cttcttttaa tggaattaat atatctcctg
    69121 actcagataa aactgcatct gttgattcaa aaaatatctt agacgctcta gttaaacagt
    69181 ttgggcacaa ctcttgcata tctggcatat atgaacctac tgcacttatt aaagctcctt
    69241 ttttcactaa gtttccatta agtactggtt gttttgatgg agtagctaaa actatcacat
    69301 ctgcgttatc tatggcttcg tcagatgatt caactgcaac tattttagta ttatatttac
    69361 ttaattttaa gttcatttct tctgcaaatt tttctctact ttccttgttt ctactaaaaa
    69421 ctcttacctc atccaaattt ctagcttcta tcatggcttc aagttgtggc tcaccttgtc
    69481 ctcctagacc tatcaaagct ccaatcttag aatctttttt agccaatacg tctatagctg
    69541 ctccagaggc tgctccagta cgaatctgag ttacataagt accatccaat actgcactaa
    69601 cttctccagt ttctccatct aataatagta ctgttgctgg aattactggt ttgccttttt
    69661 gagcattttt aggaaataca gatacaattt ttattccccc acagcctaat tcttctacgt
    69721 atcctggcat aaataacata ctagcatctt gacttggaac agatatattg gttctcaaag
    69781 gatttacact ctttccttca caataaattc taaaagcttc cttatcagct tcaattgcat
    69841 ctctcattgt aaatactttt tttatgtcgt ctttttttaa aagtagcatt tttatacccc
    69901 caattttaat aagtctctat gctaaatatt atagcataac atttaattta atcttctatt
    69961 tcaaatcaaa taaatctaca tactctggtt ttagcataga acttatcaac gctttattta
    70021 ttgaaaattc tggtattcct gctgcatatg gagttatatc atacaaatca aaatatacaa
    70081 ctagattctc atcttgcaag taaaagtttt gattctcttt tataccttta aaattatata
    70141 ttccgatatt ttcttcatcc tttttttcaa gttcagctat ttgtctttta atttcttcat
    70201 ctataacttc tttatattta gtattatcct taaacaagtc cattaattct aaaaattttc
    70261 cagttctcat atccacatta tatgctatat cttgataaaa tccatgtgct ccaccactat
    70321 aagtataata tctcactttt atactaagag cagaatcagt attcttttta agttcaaagt
    70381 ctacatttgc aacaaactta tttttctcgt caggattatc cttaagatac tgctttgctt
    70441 ctttatatga tttattataa aattcaaata tgtcattttt tatcttatca tttgtagacc
    70501 tttcaacaat tttatttgaa tttgttatta caggcatgtt tatagtactt tctaaatact
    70561 catcattttt cactattgtt ttacttccta ttgtacttac tgataaagtt tgtttactat
    70621 ttgtattacc ctttggtaat gactggttac tcataacagt cactgcttcc ttattactat
    70681 ttaaattaat tgaagcatct ttccttaaat tattatattt atagtcatgt ttaattgcca
    70741 aaacagccat tatagtcaat gttaaaacaa atacatatct taaaacttta gcttttgtat
    70801 cgactttaaa aaatttcata ttatcatttt cctcctaaat ataaatctct cttattatat
    70861 ttggagtttc tagggttttt tatccatata atttaataaa agattaattt ttatttataa
    70921 aaaattaatc tttttgtttt aaaatattaa tatgtcttat caaacagttt gaaatttcac
    70981 caagaggtaa ttgtaacata acagaacctc tatcaaaagc taccattggc attccatata
    71041 ctatacaaga attttcatcc tgtccaattg taaatgaacc attttctttc atttttaaaa
    71101 gtccacttgc tccatcataa cccatacctg taagtattat tcctattgaa tttttacctg
    71161 ctacttctgc tactgaatca aacaaaacgt ctactgatgg acagtgacca cttattcttt
    71221 ctcctttttc acaagttaca taatatcctt gtttatccgt acacaatttc atctggtaac
    71281 ccccaggtgc aattaacaca tttccttgtt ctactctatc attattctta gcttctctta
    71341 cattcataat acactgcttg tcaagccgtt gtgcatacat ataagtaaat atagctggca
    71401 tatgttgaac tacaacaatc cctggtgttg attttggtag gtcttttata atttcaagta
    71461 ttgcctctgt accacctaca gatgcgccta tagcaataac catattatta aaacgttcca
    71521 cattaccgcc tccaaaaaat catatatcaa aaataccttt ttatcgttta tatatagcag
    71581 gttttacata tttgtattta gtactacttc tgttgattac ttctgcatgt cctacaaaca
    71641 aaaaactatc ttttttggta gcattataaa atttatttat aagttcttct cttgttttta
    71701 aatcaaaata aatcataaca tttctacaaa aaatcaaatc aaaatgttga tatgagaaat
    71761 cattcattaa attaaacggc ttaaaaatta cactttttct aatcttatca caaattttaa
    71821 atgtaccatc cttgttgtct ataaaatact tcttcttcca taactcagga acattgttaa
    71881 catttgattc tatgtatata cctcttttag ctttttcaag tgagttagtt gaaatatctg
    71941 tggctatgat tttaatgttc cacaactctt tattatatcc aaaataatca tccaaagtca
    72001 tagctattga atacgcttct tctccactag aacatcctgc actccatata tttatgtttc
    72061 ttattttatt attttcttcc caaaaaggaa gtatactatt ctgtataaac tcaaaatgtt
    72121 gaggttctct cataaaaaat gtgtggttag tactcaatct atttattagg tttatagctt
    72181 catttcctgt cctatcttta aataatagat tcatatattg actaaaagaa ctaagttttt
    72241 tctctatcat tgtattgtat aagcgacctt caattaacgc tcttttttta cttaaatcaa
    72301 taccatattc tttttttaca tggtttacaa gaactataaa ttcttcatct gtgagtttta
    72361 tcatgcaaaa acttcctcct gctaatttat cagaactaac tatatgctat taatcaaaaa
    72421 ctttcgaata tctaaaatta atatagaatt atcttcaact ttcgcaatct cttttatatc
    72481 tttattaata ttagtgttgt tagaattagt cgtctctagt aaatttagat tttctatatg
    72541 aataacatca acaactttat ctacaataat tccaacttga tactcatcaa cctttgtaat
    72601 tattatacaa gttctctcat tataatcagc tttaggaaga ttgtacttta tatgcatatt
    72661 aataactggt attattcttc ctctcaaatt aataactcca cttatatatg ttggaagaca
    72721 tggtacatac gttattgatt gaaatcttat ggtttcaatc acattttcta attctattcc
    72781 ataaataaca tcattgacat aaaatgttaa tacttgttta ataatttcat ctttagccat
    72841 actttaaatc ccctaatata tttctataat gctatctgca tctataatta aacttatact
    72901 tccatcccca agtattgtac atcccgataa acccttattt tttatattaa atcggttaaa
    72961 ataaactgga aatggtttca caacaacttg ctgattacct attatttcat caacaaaaat
    73021 gcatactgct ttatgctcat tttcaataat tatcatatta ccattcatca gattggttac
    73081 ttttgtttga atattatata ttttatgtaa ccttataatg ggaatacatg ctccatatat
    73141 tgtaattaac tctgtcttat ttccttctgt aattatttga tttaagtctg taagtttaaa
    73201 tgttcttctt atggatgata ttggtaaagt aaatagtgaa tctccaactt taaacttcat
    73261 accctctact atagaaagag ttaatggtat ttttatagta aaggttgtcc cctcatcctg
    73321 tttacttttt acttcaattg aacctccaac tttttcaata cttttacgaa caatgtccat
    73381 gcctactcct cttccagaaa attcagttat agattctttt gtagaaaagc ctggagtcat
    73441 aatcaaagaa ttgacctcgt catcagtata ctcattactt tgatgtttaa gaagaccttg
    73501 ttccttagct tttgccaaaa tcttatctct cataatgcct ctaccatcat ctgaaatact
    73561 tatcacagct tctccgccta gattttcagc agataaaact atctttccca cttcttcttt
    73621 acctttcgct atacgctcct caataggctc tattgcatgg tccatagcat ttcttataag
    73681 gtgcataaaa ggttccgcta aattatcaat tacactctta tccacctctg tttctgctcc
    73741 tatagttatt aactctacat ttttatctaa ttttttattc atatctcgta caattctatg
    73801 cattttttga aatacaccag caatttgaat catacgcata gacattacta tatcttgcaa
    73861 ttcatctgta agcttgtgta attgtcttgt tgccttattg aaattatcta tatcaacacc
    73921 tgtagaattt acgctattta caaccattga ttccataatt acaatttctc caactatatt
    73981 ttgaagtaag tccaattttt ctaaatttac actcataata ctctgcttac ttattggtaa
    74041 atgttcattt tcttcactta gactatcttt ttccatatca gttttttcat ttaaaacatc
    74101 ttcttgtatc tcatcttctg tatagttatt ttgataactt ttacttactt tattattatc
    74161 ttttaattta ttttctactg catcattgtt tgatgtactt ttcatttcta tttctttttt
    74221 actaatattt atgtattctt ttacatagag attatcttct atagttttat aaactattgc
    74281 cttatcctct ttagctacaa attgtatata aaacccataa cttttaatat actctgtaga
    74341 ctctgcattt gtttctacat cttttggata aaaatctata aattcacagt aatctctaag
    74401 ttcaaataca agcatgaaag ctctcacatt ttccatcatg caaccttgtt caaagattat
    74461 ttttactaca tcagagtctt ctttgtattc aaaatttgaa tcgattactt ctttttcgtc
    74521 tttactttct aaatttgcat tatcctttga tttcatagaa cttgataatt ccaaagtact
    74581 cacatactct tcaattcctt caataaaatt agagtaatca gaagatatac aacctcttga
    74641 ttgtaactca tctatatctc ttcttataaa atctaatgat tgaaagacta aatcaaataa
    74701 taggtcattg tctaaaactt ctattttacc ttcacgtata gcataaaaca agtcttctac
    74761 actatgtgct aaagcagata tattgtctaa ccccatcata gatgctgaac cttttatcgt
    74821 atgcattatt ctaaaagttt cattaatgtt gttatgagta aatactttct ctttttctat
    74881 ttgaatcata atttcatcta attgttcgag taataaactt gtctcaaata taaacatatc
    74941 taacatttgt ctcatactcg gttcaatata attcacattt atcacctacg acctacaaat
    75001 aattttctat tatatatgca tctcataatt taaatccttg atgattctct tatctcacta
    75061 tatgtacctc ataatttaaa tacacaatta ttctcttact tcaatatata tacatctcat
    75121 aatttaaatc cttgataatt ctcttatttc aatatatata catctcataa tttaaataca
    75181 tgataattct cttacttcaa tattcacctc ataatttaaa cccatgatga ttctcttact
    75241 tcactttcct ttagatgaaa tttttctact aattctttta aaatttgagc ctgagcagac
    75301 atctcttctg aggctgctgc actttcctct gctgttgctg agttcatttg gactactatg
    75361 gaaatttgct ctattccaga taaaatctgt gtaattgcta cttcttgact atgtacagcc
    75421 gaagaaatac cattaatata attagtagtt ttttctacac catttactac caagtccaat
    75481 gcatttgcag tctctttagc aattctgaca ccattttcta ctgttttaat agcttcttct
    75541 atgagaatag ctgtattttg agctgctttt gcacttttac cagccaaaga cctaacttca
    75601 tctgctacaa ctgcaaatcc tctaccatat tgacctgctc ttgctgcttc aacagctgca
    75661 tttaatgcaa gaatattagt ttggaatgct atctcatcta ttgttttgat tatttttgat
    75721 atttcactcg atttttcact tatttcaccc attgatgtca tcatatcatc catacatcta
    75781 cttccaaaac caacttgtga tgcagattgg tcagatacct cacatgcaag actagcacta
    75841 tctgcacact tcttaattcc atctgatatc tcattaatcg tggaagctaa ttcttctact
    75901 gaactagctt gttcagtagc accctgtgaa agagcttgtg cacctgctgc aacttgttct
    75961 gaagcacttg caacttgctc tgctgataaa tttatttcag aaaaatcacc attaaaagag
    76021 tttattatac tttctaaaga tattttaatt gatttaaaat cacctataaa ttcttggtct
    76081 atctctactc ttaaatctcc ttttgcaata ctagttaatg tactgtctat aaggtctatg
    76141 taatttaaaa gcatactttg catctttttg acagaactca ctaatagccc tatttcagat
    76201 ttactttctt caacgtctat acttgttctt aagtccccag atgcaattct tgaaaagtgt
    76261 ttttctactt tattaatagg aatcactatt tttaatttta ttactgtata ttctattatt
    76321 gtcaatatta ttaaaaggga aagtataaat attgttctta atattagact ttgtaattct
    76381 ttttttactt ctacaatttt ggaatttgaa cgggtaacta tatcctcttg aaattcattt
    76441 attaaagaat ccattttctc ttgggagttt atatagtcac taccaaaaat tatactttga
    76501 gctttactct tatcattact ttcgactgcc tttattgcac tttgttctgt tggtactaaa
    76561 gaatctgata tttcttttgc ttctaagatt ttatttgact cgctctttgt aagaccaatt
    76621 ttttctaatt tgtttaaagc tgattctctt gtttttccgt ataattcttt ttcataaata
    76681 tctttattct ttttttctcc tgtaaataca tatcttctta atacatcact tatctctcta
    76741 gttgtatctt ttatatactg actttgagtc ctcaaattat tcatatcatt aatacttttt
    76801 tctacttttt caaatgcttt ataagatgaa atagaagaaa aaatccctgc tagaacagcc
    76861 aatactataa taatcagcaa tacaattgct aatttagaaa gctttacttc tcttttcata
    76921 tctgtactcc ttcataaagt aagtttatat cttttttaat cctttcattg tactcactac
    76981 gctacaatct tttcctaagt ttttaccctc atacattgct ttatctgcta aggatatgtt
    77041 ttcttctaat gatatatttg agtttacttc tactactcct aatgtaatag tgcactttat
    77101 tttatgttct ttatagttga aatcaaactc ctttatctct ttacggattc tttctgaaag
    77161 tatcttagca ccttctattg gagtatttgt gagcattatc aaaaactctt ctccacccca
    77221 tcttgataca gtatcaattt gtctacaatt cttttttatt atacttgata ttactgttaa
    77281 cacgaaatcc cctgcttcat gcccataagt atcattgata accttaaagt catcaatatc
    77341 accaaggata agggatattg atgtttcact atatttatta attcttcttt gctccataag
    77401 ctgattaatt atatgtcgcc tattgtaaag acctgtaaga taatctctta caacgagtct
    77461 attcaatttt tcaagagaag attccagttc attatttatc ttttttaatt tatcttgaga
    77521 tttctttact tcaagatgag ctataacacg agcttttaat tctgtcatac taaaaggttt
    77581 caccatatag tcaattgctc ctacaccaaa tccttttact atgtctgtat ctgtattttt
    77641 tgaagttata aaaattatag gtatatctgc tgtacgagca ttagatttta cttccttaca
    77701 aaactcaaaa ccagagttat ctggtaaaat tatatcaagc aaaataatgt ctggtataaa
    77761 ttcttcaata aattcttttg cctctattgc attaaatgct tttttaacct taaaattatc
    77821 ttttgtaagt gttttatcta ttaagtcaca catcagaaca ctatcatcaa cgactaaaat
    77881 tgttccctgt tgcttatttt tcatatacaa acctctctta aacataatat attcaaattt
    77941 taatgattta aaatttttat acttaataat tataccacta tattcttaaa tgttctcatc
    78001 acaatctttt tataataaca ctccaactac atccctatgt tacatgatag tgcaatcaaa
    78061 cccattgatt aattcatcta ttaaaacttc atctttatct gtcaaaagtt tctccaaatc
    78121 tagtaaagta attattttac cttctaattc tccaactcca cttacaaaat aatccgaata
    78181 ttctatagta actcttggtg gaggtgatat tttacttttt tctaagctta ctatatcatc
    78241 aactctatca accacaaatc caactaccaa gtcctttatt tcagttacta ctatatacat
    78301 gcaatttgta gtcattaatt catctttttt aagtctcaaa cgcatatcta ttatcggaat
    78361 gatttttcct cttagattta ttatgccttt agaatatgta ggtagttctg gaataaatat
    78421 aatttcttga tttccagtaa tttctattac cttttcaagt tcaaccccaa aatcttgctc
    78481 atctacttta aactttagat acttaattcc ttcatcaatt agtccataat ctaaatatgg
    78541 gtcatctgga aatctcattt aatacctccc tcctaaaata cactttctat gaaatatata
    78601 ttataatttc ttcttacctt tatttattga atctacaagt aattcacccg tctcagtgta
    78661 aaaacgtatt gttctaccat aattcatacc tgtgtcctca gctaatattg gaatatttaa
    78721 tcctaaaaga gtttttttta ctgcctcaac attcctatgt cctatacttg caattactga
    78781 attgctactt cctaaaaaca tctgagcacc tccagcaatt tttgctttta tatatattct
    78841 atttgcacct atattctcca tagatttaat gagctcattt attcctgtgt cagcaaattt
    78901 acacttattt tcaatgttaa tagcatcttt actatatggc aacataacgt gtaacattcc
    78961 accaattcca gctactttat ctatcaaaca tactcctaca caagaaccaa gtgcataagt
    79021 aactaaaaca tttggtctat aggctatctt catatctgca atgttcacta ctatctctct
    79081 attcatactt ctaatcccaa cctcacgagt atttctctaa gtgagctcat ttctggaatc
    79141 atcaaaatgt gactagtaaa ataattatca ctcattttaa atttattttc tataaataag
    79201 actttgtcac caacatctga aaatcttatc ataggtacat ttagaacagc tccaaccata
    79261 tcaatacata tatctgaaat tgaaacactt atagtcatgt ttaacataga tgcaatagca
    79321 tttacatatg aacttgccat aatatttcct atttccttaa ttgctgaaat ttcaattgcc
    79381 tcaatctcat ctaaaaaagc ttcttcttta ttaaaaagag aacttagcat aagttgagtt
    79441 attgattcat ccaacaaaaa cataaacatt ccattgatat cacctttcat atcgagtaaa
    79501 atacatacta ctttgttttc tggaccacca agcaaatttg tcgcttcatt atattcaagt
    79561 atcttgacca taggtattaa tacttctaca ttgctattta tcatggatgc aagtgcagta
    79621 attgcattcc cagagcctat attaccaatt tctctaagag catctatatg aacatcatca
    79681 agttctaaat aatttataat ataaacccct ccctttatta ttgcatttat ttgcttttca
    79741 ttgtatcagt gtatatttac acttttattt taaagcatta tctacaactt taactaatgt
    79801 ttctgttttg aagggcttca ctataaaatc taacgctcca agttttatgg cttctacaat
    79861 catattctct tgtcctattg cagagcacat tacaacctta gcacttgaat ccaacttttt
    79921 tatttctctt agcacctcta aaccatcttt ttttggcatt gtaatatcaa gcaacatcaa
    79981 atcaggcttt tcatatttaa atatattaca cgcttcttct ccatcatttg cttctattaa
    80041 attattatag ccacttttac tcagagcttc tttaattatc attctcataa aaatagcatc
    80101 atctactatc aaaattttat tttccataaa actaactcct ccatatgtac aacaataaac
    80161 gcttttatct tcagttattg tctatactat ctgactattt ttcgctacac aataaataca
    80221 tttcattgat aaataaaagt aattatttat gccatattat acttaattct cttaacataa
    80281 tttgtcaaca aaaaaactta tatatctatt gtaatatatg tttggcgttt tgacgagtta
    80341 ttaaaaatat aattgtataa aacataaaaa gttatcaaaa gtaattaaat tataataaaa
    80401 caactttata ccttttttat gtttgtataa aaaaaatttt cagattcatt aaaatcattt
    80461 ctgtagattc atataggatt tgactttctc aatatctaat agatagttgt ttatttactt
    80521 aattatattt ctctatatgt attatcgatt aaattagatt tagctttata cattattttt
    80581 tatatttttc aaattgtata ctcataaatc cagaagtatt ctaatgtgtt tataatactt
    80641 tttttcatat tttaaattaa ataacaaatc attatattta caagtatcat ttatcaataa
    80701 acaatattaa atgaagaata tgtctgaaga ttcaaagtga tactgatact attaattact
    80761 aaaaaagcag taaatctttt acagatttac tgcttatagt tataaataat aaaactatct
    80821 ataataaatg tactatactc aatacttcat tcaatatagt aataacaaat ctactttatt
    80881 cctatgtaaa tatgaacttc ttgtttcttt gtatcaaaag tattacattg atactcttca
    80941 aaatcactta tataagtcct atcaaaatcc atttgccaaa acttaaacca aaaatctcct
    81001 acttcttttt gacctcctac tataacaaac tttgcatact tacctgctgg tataacttta
    81061 ctaataatac tttctccaac agtattatta gtgtttaatt cttctaaatt cttctcttta
    81121 tcagaattac tatttacttc acaacatgca acaaagctat acggacttgt aaaatcaccc
    81181 tggtaatctg tatatagacc tattgtcttg tcattctttt taccctttat agcattatat
    81241 atccctttgc ccataaattt tttccacaat tcacctatat catttaccgc ttgtccatct
    81301 ttatttgtag tctccttcga tattcctata actattttct catttatctc tactatttca
    81361 taattcatac tttatacctc actttgtttt tattaatata ttttattttg aactaattca
    81421 attataattt ataatatacg acacctttat gtcatatttt taatataatt aaactcagtg
    81481 agatattata tactaaatgc aagatattat atatttaata aaatctttaa tctagcatta
    81541 tattataatg aataaatttt agacaactcc cttagtctag ttattacatt atccctaaca
    81601 tctttaggtt caagtacttc aacattgtca ccaaacgata aaatatatcc ataaatccat
    81661 tcaccaatag gaaattctgt aattacatca tatgtatcat cttcattttt agttattaaa
    81721 tccttattaa aatcatcaaa tactctaaaa agcatctttt ctttaaacct caatttcaac
    81781 gttatagtat tttccttaat tactttagaa tcattcaaac atacttcttc tattatcttt
    81841 cttgaaaaca cttcatcctt tatagataaa ttccttatcc tactaattct aaatatccta
    81901 aaatcatctt ttagtttaca aaatccatac aagtaccaag tcttactctt atacataagc
    81961 ttcagtggtt cgacagttct gtttgtctgg cttgacaaac tatttacata attaaaattt
    82021 atagtattac gccttaaaat agcttctttt atttttgtaa atttatcatc ttcattaaaa
    82081 ttacttcccc attcagtaaa gtctatttca atccagtttg aaaaattctg ctctccaaat
    82141 attgagccaa ttttatttac tactgaattt atttctggat acttagtcgc ctgtaatgtt
    82201 ttcagtgcaa ctattaaact ctctttatct ttttttgaca atatagcctt gtctatagaa
    82261 tattcttcta ttaaagatat ccctcctcct ttgcctttcg tcatatatac tggtactccc
    82321 gacatagaca gagtttctat atctctatat atggttcttg tagaaacttc aaacctatct
    82381 gccaactctt tagctgttac taatttttta tttaatagaa ttactattat ttctgttaat
    82441 ctatttattt tcattcatta ccacctacta aaattattaa atttatttaa tctaaattaa
    82501 tcatactaat ttttaaataa acaaaatctt agaatcttat ctaaattatt cttacatgat
    82561 tttatttact ttctattatc tttctcactt tggatattat catcttaatt tatttattac
    82621 tatatcaatt tacttattat catctcattt gttatcgtct tacttaattt acttattgct
    82681 atatcaattc cacttattat catcttattt aacttactta tttctatatc aattcactta
    82741 ttattacctc acttgttatc atcttactta atttacttat ttctatatca atttacttat
    82801 tatcatctca tttgttatcg tcttacttaa tttacttatt gctatgtcaa ttcatttatt
    82861 attatctcac ttgttatcgt cttacttaat ttacttattt ctatatcaat tcacttatta
    82921 tcatcttaat tcatttgatt attatcattt actttattca atttctatat caaaaattag
    82981 tatttgtact taatacttaa aattaattta aagtctttac atattattta ttttttattg
    83041 taatattcat ttccatactt tactaagcta cttccactca tttattttaa aatttcaatt
    83101 tactatttct caattctata ttattatttt tcaattttat attactaatt ttaaagcttt
    83161 ttagctatta ttcctacaat atttaaacaa ttttttcata atgaagctat attacaatat
    83221 attcaaaata tgtaatattt tagatatttt tcgttgacaa tgttaaattt ttgttttatc
    83281 cttaattaag gacatgttat tgacatttct gaaacttatt tgaaatagtt ttttcatttt
    83341 atttaggaaa acgtattata cttaagaaaa cgtattttct catttcagat aagtaaaata
    83401 tttattcttt tgaggaggaa atcatggaaa ttaataaaaa acattttatt caagtatttt
    83461 taacttgctt aatcttggta gtaatatgtg aatttatagg gcaaagaact atagctattg
    83521 gaaaagcctc tatagtactg ttccctatgc tttatgcagt tataattgga cttataataa
    83581 caccagattt attaggtaaa aaaattaaag cacttaaaaa agtggttgga gaaaaagaaa
    83641 taaatattgc tggtgaagtt gttggaattg cactagtaat gcttggtata aaatatggta
    83701 ctacagttgg accaaacatt gacaaaataa ttcaagctgg accagcgttt atcgctcaag
    83761 aatttggtca tatacttgca ccaatcgttg cattacctct tgcattaatg tttggaatga
    83821 aaagagaagc tgttggagct actgcaagta taagtcgtga accttcttta ggagttatat
    83881 cagaaaaata tgggataaac tcaccagaag gtagtggtgt acttggtaca tatttaatgg
    83941 gaacagttct tggtactata tactttagtg tactaggttc aatatctatt tatagtggtc
    84001 ttcacccata tgctttggga atggcctgtg gtgttggtag tggaagtatg atgacagcag
    84061 ctgctggttc attatctacc atggtaccac ctgaaatggc agatacaata cttgcctatg
    84121 ctgcaacaag caatatgatg tctagtataa caggaattat attcttagtt tttgtatcct
    84181 taccatttac taattttatg tataagattt tagaacctaa attttcgaga aataaaaaaa
    84241 ctaaagaaat taaatctaca gaaggagagt gctaataaat gtttgctaat ttaaatttaa
    84301 agaaaagttc atatcaatta ttggttatgt ctgttattgg agttataatt cttataggac
    84361 aaagaattag cgttggtaca tctatagtta cagctcttcc tggtatggtg atgctaatat
    84421 tagctgctat ggcagctatg attataaaag atttatttcc taaatcaatc tttccagctt
    84481 ttggatttgc aactataatc ggccttttac ttagtatgcc atatagtcca acatctgaag
    84541 tattcttaac taacactaat aatattaact ttatggctat aactactcca ctactagctt
    84601 ttgcaggaat ttctgttgga aacaaaatag aagctttaaa agaaatgtca tggaaaatag
    84661 ttataatttc acttattgta tttacaacta tattctttgc atgtgcgagt atagctcata
    84721 tagttttaag tattcaaggt aaaatatagg aggaatttat tatgaataaa gaacaattaa
    84781 aatctctagt aataaaaact atagatgaaa atagagaaaa aatattaaaa ataggtcaag
    84841 gaatatacaa aaatccagaa tatggatata aagaatttaa aactacagaa gctgtttcaa
    84901 acttttttga gcaagaatta aatttatctg tagaaaaaaa tatagcagtt acaggatgca
    84961 aagcagatgc aaattctagc aagaaaggtc ctcatatatc tatacttgga gaattggatg
    85021 gtatatcatg taaagaacat aaagatgcta atgaaatagg tgcttctcat acttgtggac
    85081 ataatattca aatagctgga atgttaggtg ctgctgttgg tttagtaaaa agtggcgttt
    85141 tagaacattt agatggtaaa gtatctttta tggctactcc tgctgaagag tttattgagt
    85201 tggaatacag agagcaatta aaaaaagaag gaaaaataac ttattttggt ggaaaacaag
    85261 aattaataaa aagaggttat tttgatgata tagacatatc tatgatgttt catgcttctg
    85321 atttaggaga agataaggct ctagttggtc ctgagagtaa tggatttgtt ggaaaaaagg
    85381 ttaaatttat aggtaaagaa tctcatgctg gttctgctcc acatgatgga ataaatgctt
    85441 taaatgcagc aatgcttgct ataaacaacg tgaatgcact tagagaaact tttaaagagt
    85501 ctgaaagagt tagattccac cctatcatca caaaaggtgg agatatagta aatgttgttc
    85561 ctgctgatgt tcatatggaa tcatatgtta gagctagaac tataaatggt atgattgatg
    85621 ctaatgaaag aataaataag gctttgatgg ctggtggaat ggcagttgga gctgatgttg
    85681 agataactga aattcctgga tatcttccaa tattacgata caaaagtctt gataatttat
    85741 ttaaaaacaa tcttgaagat ttaggtctaa aaggaaaagt tattgatggt ggagatttta
    85801 caggctcttt tgattttgga gatgtgtctc atataatgcc tactcttcac cctatgattg
    85861 gtggtgtaaa aggagctctt catacaagag attttgaaat agttgatgaa gatttagctt
    85921 acataattcc tgctaaagca atggcactta cagttgtaga ccttcttttt gataatgcta
    85981 aggatgctaa agatatatta gataccttta ctccagttat gactaaagaa gaatatctaa
    86041 cattcttaga aaaacacgat aaaactttat aagtctattt ttataatagg gtggtatcta
    86101 ctgtaaaagt tataccactc tttgtttttg taacagtata cttcttttct tttagttttt
    86161 agattaaact aaaatatatt atcctcctta aaacttttag agctacgttg aaatatcagt
    86221 agaactatgc tatattcttt ctaattaata taaatttcta ttctaattca aggtggtgaa
    86281 aaaatgttta atgcaggaaa tcgaattata aatacatggt tgtaccctat tcaagatggc
    86341 tttgtcttga ttgatactgg atatgaaaat ggttttaaac atttcaaaaa acgaatttct
    86401 aaattcaaca taaaaatcaa agatattcga tacatatttc taactcatgc tcatgatgac
    86461 catgttggtt ttctaaatca gattctagac gaatctccta atacaaagat tgttatgcat
    86521 gataaagctt tagaaattct atataaaggt caaaactctt ttattggtgg ttgtaccagc
    86581 cgtactgcct ttctcttttg ccaaattatg aaactatttg gaaaaggtga gcatagtttt
    86641 tctccactta aacaagaatt tgaaaaaagg tgtattcttg tgtctgacaa gaatcgtaaa
    86701 gaaattgaaa aagaactaaa tggaaaaatt atagatacac caggacatac tgatgattca
    86761 atttcactac taattgatga aggtgtttta ttttgtggag attctgcaat gaatggattt
    86821 ccaagtactc acaaaattac catatttgca gaaagcaaac tagaatttat tcaatcttgg
    86881 aaaacaatca tcaatacaaa acctaaaatg atttatcctg gacatggaaa accatttgaa
    86941 tacagtaaat tagaacaaaa tctaatctat gtaaataaaa taaatttata tcctctacat
    87001 aattcaaaag atattcacag atttttgtag aaaatacaaa gtaaatttat ttgattaatt
    87061 aaaaaatcta acactttact acgctactta ttttaataac ttaatcttcc actagctttt
    87121 cataaaattt tgttttaaaa ttaattttaa agtgcatatg ttatttaaat acattagata
    87181 aaattcgtca ttaatctact taaagcatat ttaactaaca ccactcaacc agaaaattca
    87241 gaaaactgca ttgacacagg aaaaagttta ttttatactt tttttaggac atattgtgga
    87301 cacgtcttaa atcgacaaac agaatttaaa ttgtaagatt aaccacaata cttatttttt
    87361 aattatattt ttaaacatta gggaggatat tatgaatgat aacgtagtta agaagaaaaa
    87421 cttttttgac aggacattaa acagaataga aactgttggt aataaactac cagacccagt
    87481 tacaatattt ttagggttat gtgtactttt acttatacta tctagtctag ttggttctat
    87541 gggtatatca gtagttcatc ctggtactgg agaaactata accgctgtaa atttattgac
    87601 tgtagaacag cttcaaattc ttttaggaaa catagtcagc aatttccaag ggtttgctcc
    87661 tttgggtcta gttctagtaa ctatgatagg tgctggtgta tgtgacaaaa caggacttat
    87721 gacagcaaca atcaaagcat cagtaagcaa gattcctgaa acaagagtaa ctcttgttgt
    87781 aatgactata ggtatgcttg ccaatatagc ttcagatgca ggtacaatat tatttccacc
    87841 attagctgca cttgtatatc ttggtgttgg tagacatcca cttataggtt tattttctgg
    87901 atatgcagca gtctgtctag gatttgccgc aaacattatg ataagtgtca atgatatact
    87961 tgctgcaagt tttacagttc cagcagctca aatgattgat tctggatttc aagccaatgc
    88021 aacaatgaac ttatttttta tgatagcatc aacttttgtt ctaatacttt tggcaacatg
    88081 ggtaacagaa aaaattgtag ctcctagatt tggtaaatat gaaggaaatg cagaactaga
    88141 tgttgatgga agtcttagtg atgtagaaaa gaaagggctt aaaaaagcta gtataagtat
    88201 attaatatat gtggctatta tagtagctct tagtgtaatc ggtaaaaaac cattcttagc
    88261 tgacccagaa acaggagatt tactatcaaa caatgctcct cttatgaaag gtatggtacc
    88321 tataatagca ctagcatttt tcatacctgg tgttgtatac ggaaaaacta taggtaaaat
    88381 aaagaaggat aaggatgtag tctctataat ggctagtgca atgagtgata tgggtggata
    88441 tataatacta gcatttgctg cttcacaatt tttgcaatta ttcacaaata gtaatttagg
    88501 tctgatacta gctgtaaagg gcggagaatt tttaaaatca gcaggaataa atggaccttt
    88561 attgttgata ggatttatta tattatcatg ttttataaat ttatttatag gtagtgcatc
    88621 tgcaaagtgg gctattcttg cacctatatt tgtaccaatg tttatgatgg ttggatacaa
    88681 tccagcactt actcagatgg cttatcgtat aggtgattgt ataacaaatc cacttagccc
    88741 attatttccg tacttcccta ttatactagc attcacaaga aaatacgata aagatgctgg
    88801 tatgggtact gtaattgcta atatgatacc atactctata tcattcttaa tagtgtggac
    88861 tatactatta atattgttta tggtatttaa tattccacta ggacctggaa tacttccttc
    88921 atatagcatg taatttattt aaatctttct aaaaggagaa ataatttatg ttagataaaa
    88981 atagacttat aaataatttt atggatatgg ttagaattga tagcccatct aatcaagaat
    89041 tagaaatgtc taagtggttg gtaaactact taaaagaaag aaatatagac gccattatag
    89101 atgatgcagg taaaaaatat ggtggtaata caggtaatgt cattgcctat ataaaaggtg
    89161 aagaaggaag tagaccactt tgtttatgtg cacacatgga ccaagttcaa ccttgtttag
    89221 gtgtaaaacc aatactagat ggtaatgtag ttagaagtga tggaactact acacttggtg
    89281 cagatgataa agctggaata gctgctatac ttgaagcttt agaacatgtt attacagaaa
    89341 aaataccaca tagagatatt tatctttgtt ttacaatctg tgaggaagct ggtatgcatg
    89401 gcgtcaaaaa ctttaatcct gacaacttgc cttgtaaaga tatggtgatt ttagattctg
    89461 gtggagctat tggttcgata gcatacaaag ctcctgctca acaatctata aaaatctctt
    89521 ttcatggaaa gaaagcacat gctggtatag aacctgaaaa agggttaaat gctatattag
    89581 tagcctctca tgcaataagc aacatgcaca taggcagaat agattcattg actacttcaa
    89641 atataggtaa aatagaaggt ggtggagcta caaacatagt aactgataag gttacattga
    89701 ctgctgaaat taggtctcat atacctgaaa ctttagagta tgagcttaat catatggaaa
    89761 aatgttgtaa ggatgctgca tctaaattta atactactta tacttttgaa cataatatgt
    89821 cttaccctag ttttgaactt agtagagata gtcacgtttt caagttaagt gaagaagcaa
    89881 taagacaagt tggtgttgtt ccaaatccaa tggtaattgg tggtggaagt gacgcaaata
    89941 tattagctaa tcttggatat aattgtgcta tattaagtct aggtatgtat gatgtacaca
    90001 cagttaatga atatgtaaat atagacgaat tatatgatac tgccaaaata gtttatcata
    90061 tgattaaatt ataaatatca taatagaact ctttaaatta taaaaataaa aacctatgta
    90121 tcttcaactt tataagttat atattagagt tgttttacat aggttttagt atttttataa
    90181 taatttgttc taattttttt cataataagc tttaatactt tatatagtaa tttgttgtag
    90241 aattttatac aatataatga tttatacagt tttataaaat atcttaaaac agtatttcag
    90301 taatattttt tggtcttcct ccaccaatac tagtctcttt tgcacatatt cgacctaaac
    90361 ctgcatttac tattttattt aatatacgtc ttgcacttct ttcacttaca tttagatact
    90421 ctgctaactc ttttgaatca taaatcttac tttttctatt ctcatttata gcaataattt
    90481 ttgcaactga ctcacaactc attccagtct ttttagatat ttcgattacc ttttcatcag
    90541 atagcatcaa agaataattt aattcatttt cggaagctaa aggtcctctt atgttttcat
    90601 cttcatctac caaatatata ccaatttctt ttgaatctat ggagtgtctt aatgctttat
    90661 gtgcattatt ttcagcctga tacgcagtta ctccagtacc aattcctata ctaagagaaa
    90721 agcccatgtc ttttatctct ctctttagat tgaatagctt atcataatta tactcattat
    90781 cagctacccc tttatgaaca aatacaacat aatcatttct tccaagtaaa aataaggaac
    90841 cttgaatgct tcttacatag tttactacaa gcttatccat atctgatttt tttatcatgt
    90901 cagaataata gttatctatc ttctctttat aatctattaa actcaatatt tcaacagcaa
    90961 tttgagaaaa tcttgcctta cttagagcat attcactctt taccttgtca taactttctt
    91021 tgattaattg tatagtagct tgtaaacgaa atacaggata tcctctttct tttaattcat
    91081 tatatactgc accaaaacca gtcaacatta tatccgtctt attttcttca aataatttta
    91141 tatgccattc tacaagttca gattctccta cttccaaaga aaatggatta caaaatacac
    91201 tcgttgcttt aatgtcaaat tctttaagtg catcttccac aacatatcta tcaactacat
    91261 ctatactgaa tttatctaat tttatatttg cactttttat tgcccaaaat gccttcatta
    91321 tactcgtccc acttctcggt acaaatgaat gtggcttact tatctcatac ttagatttta
    91381 taaattcata aactgcacat cctgtaaata taatagcatc acattcgtct tcacatttag
    91441 aaataacttc tattgtatct actacttttt ctcttacata tattttagtc tttaaatcac
    91501 tgtctatctg ttttaaatca tcctttatct taaacccaga gtctgaagga cctataatac
    91561 ccactatcat aaacttcgct cctaatccat aaatattata ctttttaaaa attatatcct
    91621 cactattttc tacttctatt taattatttt gaactactcc atcctaccta catttagaat
    91681 ggaataatta gcttattttt gataaagtaa cttctcaaaa tcagcacttg gaataggctt
    91741 acaataataa taaccttgaa ttaccacaca atctaaactc actaaaaatt cagcttgttc
    91801 ttttgtctct acaccttctg ccactacatc catatctaaa tcttttgcca tggctatagt
    91861 gtgctttaaa actatttttt ctctgtctgt gattccttcc tcattaaaga aaccacaatc
    91921 tatctttaat gtatcaatat taatattttt taacatattt aatgaagaat atgctgaacc
    91981 aaagtcatcc atatttaaaa caataccatc cattctaagg tcggctatta tcttagtaaa
    92041 taattttata tttttaataa ataaactttc tgtaagctct aattctaaaa aagattttgg
    92101 tatactatat ttatttatta aacttaaaac aatttcttta aaatgtggat tatgcaaatg
    92161 taatcttgat acatttacag agataggaac tggctcttca cctaaatcta tccattttct
    92221 aatcaaagaa catacttgtt cccatacata catatctaat ctgataataa acccattctt
    92281 ctcaaatagt gaaataaatt taattggagg tattatacct ttttctggat gaacccatct
    92341 aaccaatgct tctgcaccaa caattttatt tgcattaaga ttatacttag gttgtaaata
    92401 tacatggaat tgcccatttt caagtgcgta ttccatttcc ctttccatct gtttttcttc
    92461 aagtgcatca tttcttatag tatcatcata aaatatatag ttgttgatac tttgtttctt
    92521 tacttttttg tgagcatatc ctgccatttc acacgcattt gtaattggaa tatgattatc
    92581 caaaattcta taaactccaa aacatggtac taacatatat tcaaattttt ttctatttaa
    92641 gctattttta atcttataaa ttaccttatg aatatctcta tcagagtaac tctcataaaa
    92701 aatgcaaaat acatctgcat acatacgaca acatatacca ttagaaccaa tgtttttttg
    92761 aatcaactct gcaacatata ttaaagcttt atctcctcct ctaactccat aaatgtcatt
    92821 aattaccttg aacttatcta tatccatcat tataattgca taacgcttgt caggatatct
    92881 tttaagcatt aaacttattt gttcacaaaa actttcataa ttgtatagtc ctgttaatgt
    92941 atctttttgg tttttatgta gttgcataag ataatctata ttttttatag caactaaaat
    93001 atgtgtttgt ttctcaccta acttattttt actactaatc tttaacatat aaattaatgc
    93061 ccaatagtac tttttatcta ttcctaaacg tctatactca aaatttagtt ctaaatcgtc
    93121 ttgcttgcta ttattaagac tatcaagaga ttttagaagg tggttatcat taaataatat
    93181 tatatcatca ggatgaatta aatgtttttt tatgtatgaa aaagtttttt caagattttc
    93241 ctttatagga aaactaaaaa tattgctctc tgattgataa attggagtaa ttaaattcgt
    93301 atcaatgcaa atagataaaa ttatatcata tgtattataa gctaattttt cataagcctt
    93361 agaataccct tttatcatta aatcatcaaa ataaacctta tcaactaact ctttatgttt
    93421 aaataaaata ttattcgtcg aatcagctaa gtcactaatt actttcattt cattatttct
    93481 aagtttgttc ttattataat acctcttctt atcttggtac attctctcat cagcaacttt
    93541 aattagctta tgtatatcaa tattatcgtc actccaaata ctgcccactg ctacactata
    93601 tatcatctca tccttaaatt cttcacttaa ccaactcact aattcttcaa atagttgttt
    93661 tgatatatct tcacataata caacaaactc atctcctcca atacgataaa cattataaga
    93721 atgaaagtat ttttttatta ttacacatgc tgacacaata gcagaatcgc cattagcatg
    93781 tccaaagtta tcattaatat cttttaaccc atttatatct acaaatacaa ctcctatgga
    93841 tttaactttt cctttttgaa aattatctat atacttaata tatttatttc tattatatgc
    93901 accagtcaag aagtcatagt agctcatata atttaattta ttttctactt ttcttttttt
    93961 catctcagtt aataaaaaat aagataggga tgtcaaaaga gaggtatctc caacagcttt
    94021 atgtggatta tcaactccaa taaaccctac tactttatca tcttgtttta gtgaagatgt
    94081 cattaaactt tcaatttttt gaggttttaa aatttcatat tctattggct gttcttcttt
    94141 tatattttct atatcatcaa ttattacaaa acctttttgt tcgaataata aaaaccaatt
    94201 ctttaattca ttaatatcaa gatttgttag tgcctgtttt tgttcatcaa caccttcatt
    94261 gcaccattca tatgtattag ttacttttgt tctatcttct gatacttcaa aaacatatgc
    94321 tctatcagct ttatgaaatt taccaatatt ggttaataca agatttacag catcagaaaa
    94381 attagattct gttataagat gtttaataca tccaactaat aactccttta tctctaattt
    94441 ttctgctatt gacttactta tatcttcctt ttctgtaata tcaagagcta tttctaatcg
    94501 tgcatgtttg ccctcccatt taattaactt gtcctttaat ataaaatgtc tatttgttcg
    94561 agtattcgta ttttcccata tgtaatattc atcttctttt aaaatagagt ttgtacaaaa
    94621 ttcgcaggga gaatctttcc cctgtaatgc tttataacat tttaaatggg atatatcatt
    94681 aagtcccatt gcctttttcc caatttcatt aatatataaa agttcatatg tatctaaaga
    94741 agaaacatat acaatttcat ccaactcatc tattaaattt attacatcca tttatatata
    94801 tctcctttta ttcattttcc agattgaatt tttaaagctt ttaaaatttt gctatatatt
    94861 tggcaatgat attatacttc tttatgtttt aaaatagtac cttaatgagg ttctattttt
    94921 tagtaaatag aattattatt gtgtcaatcg tacaatagag ttttgtaata cttaatttaa
    94981 tatatttata attaactatc ttattatgta tttacaatta attctcatat aaatgacaaa
    95041 tctccacctc aattaagtat tccaatcata tatgaggata atacttcatt catttaaaaa
    95101 tataaaacta ttatatatta aaatttcttc aataataaat tatttagatt gttactttga
    95161 tatattatat aatatcacaa aggctgatat aaaaagacaa aaagggcaat ttttttatat
    95221 caaaaaaaat gttaaattga tattatccat atataaattg atattatcca tatagatgct
    95281 atatttaaca attctactta cttcccttac acttattagc atatagttat taagagtttg
    95341 ttgcaaaaca acacttagca cactttaaaa agtatggtct aataagtaat caacgaagaa
    95401 gacataataa agcataaaat atgatatact tttccacgcc atcaaaactg aggattttat
    95461 tattaatata tgctaaaata tgcttaataa attaaatttt aatgggagaa tagttatgaa
    95521 aatatttagt ttcttgttgt ttgtgatagg aatatgttta tgtattgctg gatttatagg
    95581 acattaccca gtatttgttg gtacaacatt gagttttctt gcaattgcaa tgatagctgt
    95641 aagacaagtc aaaactaaga aaaaaatgaa ataggcaaat cctaacttta caagttaata
    95701 ttacacaagt aattagtcta aaattggata ctttttctat tacagaaata catcatccac
    95761 tttgtatttt cttaaaaaaa taaaatagct atgtaaattc aagattagat agattaactc
    95821 tctatccatt tcattgtaaa atatacatag ctatttgtat tcgatttaaa atacttagat
    95881 tttcttacat aacaaataat ttctatctga ttattactca tattcattta gtaatcactc
    95941 agcaactaat catttagtat ctattcatcc gccatacggt aacctacccc aacctcagtc
    96001 aaaatatatt ctggctgagc aggattcttt tcaattttcc ttcttatact tgccataaaa
    96061 actctaagcg actgattttc actttcatag taatttcccc aaactttatc tattataaac
    96121 ttatgggtta agactcttcc tgaatactta gacatcaact caataatctt atattcgatt
    96181 ggagttaaat gtatttcttc accattaatt gacacaatat gattttcata atctatcttt
    96241 aggtttttaa cttcaaaaga ctttggagca tcattattta tattatcctg ttgagcttta
    96301 tttctaagag ccacacgcac tctagccaaa agctctgtta cactaaaagg tttagttaaa
    96361 taatcgtctg ctcctccatc taaagcttcc accttatccc tctcatgctc tctcgctgaa
    96421 acaacaatta ttttattagt ctttgcacat gccctaactc gtcctattac ctcaatccca
    96481 tcaatatctg gtagtcctaa atccaaaatt atcaaatctg ggtcaagaga atgtataagt
    96541 gatatagctg ttcctccatt atctgtctct acacacctat aattttgagt ttcaagagat
    96601 acttttataa atttacaaat tggcttatca tcttctacaa ttagaactaa tggctttatt
    96661 tccacttgtc tttcccctcc tcatcataca taggtatgct aaatctaaat gtagctcctc
    96721 cagaaggatt attaaaggcg acaatttctc caccatgagc ttctactata gatttacata
    96781 tctccaatcc aagaccaata cctcttcttt caagatttct agacttattc ttagtataaa
    96841 acctattaaa aatattcccg atatcttcat ttggtattcc ttttccatta tctgcaactt
    96901 caaatagtac ttgatttgac tcttttttta cagttagttc tatcttagaa tttttaggtg
    96961 tatgccttat agcattatca attagattta ctaacacttg ttctattaat aatacatcca
    97021 catgaacgat tattatctca tccggaatat ttgtttttat gtctctacta ttggcaaact
    97081 ttttgactct taatatagat tcagctatta tttcatcaac aacctctggt cgtttttcaa
    97141 tatccaattt tccttcatct attctggtca tactaagtat attctcaaca gaatgagtta
    97201 gccaactcgt atcttcatat atatttttca ataattctac tctagtttct ttatctatca
    97261 catcatcatt ttcaagtatt gttgaagatg aacctaatat acttgtaagt ggagttctta
    97321 aatcatgaga aattgaccta agcaagtttc ctcttaatct ctctctctct gcctcaagat
    97381 ttgctttttt atttttctca aataaatttt ctctatcaat tgccaacgca acctgtgttg
    97441 aaactgcttc taatagtatc ttttcatttt ctgtaataat atctatctta aaacacgcaa
    97501 cacctataac accaagaaca tttgattctt gaccttttat agggaaataa tatgcactgc
    97561 tgtttttaca atattttgtc ccaattccaa ctgggttacc tgtcctaaaa gcttctttta
    97621 tagcttcctt ttctaatact gaatggaata tattctcact tccatcattg ttacaaatat
    97681 aaatacttgg cttacctaga ttattattct catctgcaat agtcactatt acagttctat
    97741 ttaatatatt tactaaatta gacccacaaa attcaataat ttgattttta ttttttgctt
    97801 taagcaacgt tttgttattc tcatagagca atcttatcat tttttctctc ttatgagaaa
    97861 gtctcacttc tctttttatc ctagaagtta aagtacttgt tataattgct gccattagca
    97921 taatacaaaa ggtcatagga taatcttttc tataagctaa aaaagtatat aatggatgcg
    97981 taaagaaaaa attaaatgat agcactccta ttactgaaga aagtattcca aaaaaatatc
    98041 cataggttat acttgtagca aatagtacac ctaatatgta tactagtata atattagatt
    98101 cattaaaacc taccttttca aaaactactg atattccagt agcaattgtc ataaccaata
    98161 tagtttttat gaagtcctta ataattatct ttttactgag atagccatct tcatcataat
    98221 catactcttt taagtcttca tgttgtagtc gttccttttt catttactac aattcctcct
    98281 tattgttact gtttaaattg gctctatttt atataataca attttatcat aataaattca
    98341 atcaatacat ttaattaatg tacttaaatt actaaaaggt gctgtcttaa aatgaaaata
    98401 aatctctatt tcaaaacagc acctatatat ttaaattact aatttagttt ttacatactt
    98461 aaatcaatag ttttattcaa tttcataaat tataatactt caattataaa acatttctat
    98521 ccaacaagca taaatataaa gtgggcacat atacctgcac ataaaccacc tatagtatgc
    98581 gaaagtatcg ctttaccagc caatggtctt gcatctaaag catccatcat acctatgtgt
    98641 gtacttaaat atccactcca acacataccc attgctgtga atactgctat atcattagga
    98701 gttatagcgc ctgattttat aaactctggt actaaagata ttgctgctcc aacagctcct
    98761 aatgcagtta cagggaatgc tattgcctct ggtgatgtga atccaaataa tggttctatt
    98821 atgaagctaa tcttatcacc aatagcaggt aataatttta taccttcata tgcagctcct
    98881 gtgtaaacag cttgacctgt agcagggtct gtagatggtc caaaagttaa taacataact
    98941 aatgtacaaa ctactaaaac tcctggtatt atagccatac ccatttcaac acctaactta
    99001 ccaccttcaa gtatagcatc caatgttctt tggaatacat taccatctct tatttctcta
    99061 aactcttcaa gttttgcacc tttatcattt atttgctttt cagtatcatt tttagggtca
    99121 taattataat actttttagt aaaagtcaac ataattctaa cactaataat actacctatt
    99181 attgccgcaa cattacctat tatagctggt agtacatatt ctttaccttg agctatcata
    99241 aaagttgtta caataagtcc cataccaaag gctgttccta aattacataa agcaggtact
    99301 tgatacttct taaaatattg tgtaaatgtt ttgtctttag caaatggtat aatagctgga
    99361 ttatcagata aatatgttgc aactactcct gctatactag caccaggtaa gccccatata
    99421 ggtctcataa gacccttaaa tatcttatta actaaagata ttactccaaa ctctgaaagc
    99481 aatgcactaa gtgcacctgc aagaactgcc atagccatta ttaaaaatac tgtgtctaat
    99541 aaaagcgcat gtgctgtact cattattact ttaaacatca ttcctgcacc catgatgctt
    99601 cctacatatc caaatcctac cgccaatagt acaataaata cgaaggtttc catacttact
    99661 gccttgactc ttctcttatc cgacagcttt tccatcttga aatcttcccc cttttaattt
    99721 taaattaagg ttcctaacat tggtacaaat tttttggtac aaactgagtt ctaaaactta
    99781 cactcgtaat gcaagttgtc agttttttga aataaaaaaa aattacgttt atagaataag
    99841 aatatcctct ttaatttgga tactcttatt ctattttatg ttattatatt atcatccttt
    99901 tgtttaaaag tcaatttttt ctatttttgt tgtttaattt tatttatact ctttttatat
    99961 ttttcatttt cttttatctt tgtaagtact ccatataagt tgacttttct aaatacagta
   100021 gttataaata ccaatcctaa tgcaattgaa cttgcacacg ataatgtact caccccatat
   100081 tctacagctt ttatataatt attggtcaaa acagaataca tagtattata tattccataa
   100141 ccaggtacta atattattaa acagcaaaca cttaatgtag ttgctggagt catataaatt
   100201 cttgcacata actcacaata tatcgcaaaa caaactgtag ctataaaaaa acataagttt
   100261 tctgttactc ccatatttaa aagaaattta tacgaaaacc aagctatact tccacctatt
   100321 cctgctagta ttaagttttt tcctttcata ttaaatagca ctccaaagct taaggcagta
   100381 aaaaaagctg ctattacttc tataaacaaa tgcacttata tcccccctaa cttgaagtac
   100441 aatccaagta ccaagaacat tcctactgct atagatacac ctacaaaaaa tacttctgct
   100501 aattttgcaa gaccagaaat caactgtcca tctaacaaat ctcttaatgc attagtcaaa
   100561 gcaagcccgg gaactaagag cattattgct cctgctatta aatggtctaa cgtctttatg
   100621 aatccgagct ttaaaattaa aattgaacaa gaagctataa taactgctcc aattgcattt
   100681 acaaaaaagt cattaaggga agatttactt aaatacataa taacaaactt agtcagaatc
   100741 ccaacagtaa atgcagctat aaattcttcc acatttcctc caaataatat cgaaaaagtt
   100801 gctgctgcaa tacctgcaaa aaatattgtt attaaatccg agtaatagtt atcttcactt
   100861 atttcatcta aaattttctc acataattca atatctaaat tatttatact tattgctctt
   100921 gataatgagt taacttcatg aaccaagttt aggtctactc ttcttgagct tattctttta
   100981 attgctgaat gtaatttccc atctacaaat acagatgcca ttacagctgt tggagttgca
   101041 aatacatcta catggtctat tccaaaagat tgacatattc tagctatcgt ttcttcaact
   101101 ctataggttt ctcctccact ttgcaacata gctttacctg catttgagga aaagtttaaa
   101161 attctatcta tatccacaaa acatatctcc cattctttta tagtattatt catattttaa
   101221 tacaagatat tatttattta aactatttta aataattcat atccaatatt tacattttat
   101281 gaaaaaactt gttttttatg cttgtcaaaa tcaaatttta agcttgttta caccataaaa
   101341 tggctgaatt aatatttgac aaacactttc aaccatttat ataaccttct aaattgtata
   101401 actttttact acaaataaaa ttatatctct tttaattctt tctcttgagt atttagctta
   101461 tagtaacttc atatttatat atgtacaata taaaacatta tttttatgat acaaaatata
   101521 atttgtaaat gtatatatgt attaactgtg tatatataaa ttattcttaa ccttatcagt
   101581 tttttcatat atcttcatct ataccgacca tatattaatt acattgacca tatattaata
   101641 aatgatatta catagactta agtatattaa aaaacttaaa tttagttatt taacaacata
   101701 atactctaat ttaatctata aaaatccata cctaatataa tgcaactctt attttaacac
   101761 catctattac acaaaacaac atattaaaaa gtaaaataca aaatatccac tataaacctt
   101821 attttaatgc tgaatatata ttataatata tttaatgtag cttaaatata gtttaaacat
   101881 aaagaaagga aacggtatat gctaagaaaa gataaagttc tattatctct acataaatta
   101941 tgtgaaaata tgactttaaa agaccttcaa tcagataaaa caggattcac tacaatagaa
   102001 attgctaacc attcatctct tgatagaagt aataccagta aagaattaaa taacctatac
   102061 aatgaaaaaa aagttctgaa aatatctggt aagccaattt tatttctaca tgctagtatt
   102121 atagaaaatt taattggccg tactttgaac agtgatgaat tttctataaa taattgtaat
   102181 gagctactta aatcaagtaa aaatgactca gaagatattt tttcaacatt acttggacat
   102241 gattctagtc ttaaactacc tatagaaaaa gctaaatctg ctatactcta tcctccaaaa
   102301 ggtcttaata cgttactcat aggacctact ggtgttggaa aaagtacatt ttccgaaaca
   102361 atgtacaaat atgctgtaga aagtaaaatc ttttcttctg aaagcaaatt cgtagtattt
   102421 aactgtgctg aatatgcaga aaatgctaac ttattattaa gtaatttatt tggttatgtc
   102481 aaaggttctt ttactggtgc taataaggat aaattcggca tagttgcaca ggctgatgga
   102541 ggcatattat tcttagatga aatacacaga ttaccaccag aaggtcaaga gatgcttttt
   102601 cttttgatgg acaaaggcat atacagacga ttaggagaat ctgacattgt gcataaagct
   102661 aatgtcttta ttgtgtgtgc cacaacagaa gatatacatt cttctctgct tgggactttt
   102721 ttaagaagaa tccctgttac aatcaaccta cctgctttac aggataggtc tttaaaagaa
   102781 agattatctc ttattaaata cttctttatt atagaatcaa aatacaccaa tgcaactata
   102841 aaagttcaca aagatgtaat taaatcatta ctcctttatg attgttttgg taatataggt
   102901 cagcttaaat ctgacataca acttatgagt gcaagagcct tcttaaatta caaaactgga
   102961 cttaaggata atatagaaat agatttatcc cttgttcctg attacatcta tattggtctt
   103021 ttaaaattga atgaaaatcg tagtaatcta aataaattat cagaacttga ttatatgctt
   103081 ttttatgaat ttaatggtaa taacttagaa gttgaatata caaaagaact atctaaatac
   103141 aatatagata catcaaacaa tggatttaaa tactctacag agattcctta tctggaaaat
   103201 gatataagga gtatgtttat aaattacatg gaaaagtact ctacaaaatt actttcgata
   103261 tcttcagtaa ctcattctga ttatacaagt aatgagattt ttaaagtaat caatccaaag
   103321 atttactatg ctgttgaaca ttctttaaaa gaggctgaaa aaatatcgag aaacaaatac
   103381 acaaaacaaa cttatattgc tctttcaatg catataagtg cacttataga aaatataaat
   103441 caagacacat ataatcctaa gtacaattta tataatgata aaattttctt agataaagat
   103501 ttaaatatag ctaaaatagt tttaagtata attgaaaatg acttacaaac atctttacct
   103561 aaagatgaag taaaatttat atccatgttt ctaaatagca tgtatcttga accaaacaat
   103621 caatctgaaa gtataggagt cataatactt gctcatggaa attcaacagc aagcagtatg
   103681 tgtgatgtag caaattcatt gcttggtaca aaccattgta atgcaattga catgcctctt
   103741 gatgtaaaag taagtaccat acttgataaa actatagagt tggtaaaaga atgtgacgaa
   103801 ggtaagggtg tacttctttt aacagatatg ggctctctta tagcttttgg agaacttatt
   103861 tcagaaaaaa caaaaatcaa aactcgctca attgaaatgg tatctactcc aatagtttta
   103921 gaagcagtaa gaaaaagtac actaccagaa atgactttgg atgaattagc taattcctta
   103981 agctctttaa atccatatat tggacgagca gcaatcgatt caacagaaat aaactatcct
   104041 gaaaagtcaa gagagtatgt aataataact acttgtataa caggatatgg ttcagctatg
   104101 aaagtagcag actttataaa ttcttcactt aaaaatatta gtaaatacaa tattaattta
   104161 gttcctcata atatagaaag ttttaaaatg tataagaata aatttagtaa tactaaaatt
   104221 ctggcagttg ttggaagtgt agattttaat gtagccaaca ccccttttat acacatagag
   104281 gaactactaa atggatatgg cctagatatg ctaaacaaaa taatagaagg tacattcaat
   104341 gccaatagta ttacaaatat aaaagaaaca aatctatcat acaacagttt aataataaac
   104401 tttatgaccc aaaacttaga gcttttggac tctgttaaat tattcaacta tgtcaattct
   104461 tccttattta caataataga attaatagat gaaaacttaa agagcaaatt taagctagga
   104521 tatatactac attgctcttt tatgatagaa agatgtttta aaaatacaac ttttccatat
   104581 aataacatta ctgaattaat tagtaaaaat catgaactat atagtttaat acgtgaagcc
   104641 tttaagccaa cagaagctta ttttaatatt ttgataccag acgaagaaat tgcttatata
   104701 atagacatga ttaatgagta tctaaataaa taaaatttat agcacttatt ttgtgcatat
   104761 taattaatat atgaaatgga ggacgagatt ttgaaaggaa aaataaaaca gttaacaata
   104821 cttgcattaa tttttatatt tataactcct gtatttgcat ttgcagatac tccaccagta
   104881 ccaaattctt caagagcagc actacttata gaccaggaaa ctaaaagaat attatttgaa
   104941 aaaaacattg atgaaaaaat gccattagcg agtttaagta aaatgatgac ctttttattg
   105001 gcaatagaag cagttgataa aaatcaagtt aaagagactg atatggtgaa aatagacaag
   105061 tctacagctt cagtaggagg ttctacttgt aaacttaaag atggtgatga aatatctcta
   105121 ggagagctta tgcagggtct aatgctagta tctggaaatg atgctgctat agccatagct
   105181 aaacatattg gtaaaactga aaagaatttt gtaaatatga tgaacaaaaa agcagaagaa
   105241 ataggaatga ttgatacgta ttattttaat ccaaatgggc ttcctatata tactgaccca
   105301 gaacataaag aacctcctat tgaaaatatg tcaactgctc acgatatagt tacacttgga
   105361 aagtatatgt acgaccatta tgaaaatcaa gttacaagaa taaccactat gcaagtatat
   105421 aatgatacta aaaaggattt tacacattat aacacaaatc ctctgcttgt ttcagtacct
   105481 ggtgttgatg gaataaagac aggatataca gataatgctg gatattgcct tgcattttct
   105541 atgatggtac ctaaagatgc taaaaacgaa agaaatcata gattgatagg tgttgtactt
   105601 ggtgatggta acaagaaaaa tagaatttct tcttccgcta ctttattgaa atatggtaaa
   105661 gataatttcc attctaaaaa gatagcacat aagggtgata ttatagagac tccttgtgtt
   105721 gatggtattg atgattttaa gataacagtt aaggttgata aagatttgta tggtgttgtt
   105781 tcagataacg aaaatatcaa tcctaaggta gtgtttaaaa atatgaatta tcctatccat
   105841 aagggagata ttgttggtgt tgcaaagtat tataatgact ctggtaaatt tgttggaagt
   105901 gttgatgtaa aaagtgaaag taatatagga tgtattcctt tgaaggataa gattaagatt
   105961 aaggttgcta agataaataa aaaacttgag attaaaaatt ctgtttgttt taaagcatag
   106021 taaagcatat tattaaaagg gtatgttaaa tttataaaga ctccactttg tggagtcttt
   106081 ttgtttttta caaaaaatta aaatagtggc aacaattgag gatgtgaggg agagttgcca
   106141 ctattttgta tagggtatta tattatgttt ttaagctagt tttactatct tctatgttta
   106201 tataataact cttgtgtgtg aatttaattg ataattaata tgaaaattat gtgaagtttt
   106261 gatttatttg taatatattc tactactatt ataatttttc tactggatat actaatcatt
   106321 tgtttaacat tatctgagat tgatttgcaa acttttatat aactaaatta gttatataac
   106381 ttatagattc cattaaatac cctaataatc atatatgtac atacaaagtc atgcttatgc
   106441 aaaatctgca gtttcaacta acttattata taaaccatct ttatgtagaa gttcagcatc
   106501 atttccagat tctattactc tacctttatc taatacatat atattatcag cactcttaat
   106561 tgttgaaagt ctatgagcta ttataataac tatcttatct tgtatgtact ctttcaagtt
   106621 gttcaatatc tctttttgtg aaatattatc tagagctgaa gttgcttcgt ccagaataag
   106681 taccttttta ttacttacta aagctctagc tattgatata cgttgttttt gacctcctga
   106741 tattttgaca cctttttctc ctactacttc gtccaatccc ttatctagat tttttataaa
   106801 atcatctaaa caagtaactt ctaatatctc atctaattct ttatcactta ttttattatt
   106861 taatactata ttatttttta ttgtgtcatc aaatacaaat tgatcttgag ttactatatc
   106921 aatattattt cttagtgatt ttaaattaat atcctttata ttaacaccat ctattaatat
   106981 atcaccttca tttatatccc aaagtcggta tattagattt gttattgttg atttgccaca
   107041 tccacttcca ccaacaattc ctgttacttc ccctttctca aattgtaaat ttatatcatt
   107101 taaaacaagg tttaaatcct caccatatct aaaagataca tttttaaaat ctattttctt
   107161 aatttcactg ttatctattc tatatccatt attatcaact ttaatatcta tcttttcatc
   107221 tattactgaa aatactctat tgatagacac ttttgattgt gctattctag tattcgccct
   107281 tactatagct atacatggtc caattaacat tcctgtatat tgttgaaatg ctattaactc
   107341 ccccatcgtc atcttattat ttattatttt atatccccca attccatata ttaatattgt
   107401 tatcaatcct gttagtattt gagatattgc tatattacta ctcataatga tgttcaaatt
   107461 caaatctttt tttatcaaat ctctctctct ctttaaatac ttattaaaga aattcttttt
   107521 tgaatttaat ataacaatat ccataatatt agatacgtac tcttgaatca aatttgataa
   107581 actgcctgaa tcacttctta tttcagaaat tttcttagat ataagttttg tcattttatt
   107641 ttgagaaaat gttaatatca actgtaaaaa taaaactact aaaaataaat caaactgcaa
   107701 attaattaag aaaattaacg atattatagc tgtaaacaca tttacaataa tatcaaatat
   107761 aatctctgct ccaaagtttt ctatcataaa tatatcactt tccataatgg ataaaatatt
   107821 acctgttttc ttacttgaat aatatctacc agaaagtttt gatatatggt taagcaactt
   107881 tacttttaga tttatagtaa ctttattttt tattgaagta tataaatatg ataatataac
   107941 atcaaatgta gctgataata tccttataaa aatatatatc aatattaaat ttataagcag
   108001 aaaaatattt ttatttccta ttccatcatc tattatacat ctaattagtt gaggtattac
   108061 aatatttacg ccagcaatta taaaaaccat tataaatgat actatcaact tagtcttatt
   108121 cttatatact attatattta gtattctaaa taaattatta ttaatagttt ttttcatcta
   108181 tttttccatc ttttatagtt ataattctat cagctgtctt tgcaatatta tcattatgag
   108241 ttatcataac tagtgtttgt ttgtactctt taacacacca ttcaagcata ttcataactt
   108301 catttgtagt cttactatct aagttgccag taggttcatc tgcaaatatt actgacggtc
   108361 tattggctaa agctctagct attgcaactc tttgttgttg acctcctgat agttcattcg
   108421 gatatttctt tatttgtttt tcaatcccca acttattaat taatctcata acatattctt
   108481 tatcttcttt tttcccatca agcaacacag gaagtactat attatcatat acatttataa
   108541 ctggtattaa attgtaactt tgaaatatga agccaaattc ctgtcttctt atttcagaca
   108601 gcttatcatc atttaatgta tataaatcta catcatctaa gtacacattc cctaaagttg
   108661 gcttgtctaa gcctgcaaca cagtgaagta gtgtactttt accagaacca cttgcaccta
   108721 caatagctgt aaatttatgt ggctctatat ctaaatcaat accatcaaga gctctaactt
   108781 cattctcata ttttccatat atttttttta aatcttttac cttaagtatt ttcataacgt
   108841 atctccattc ccatttaaaa aacatatatt tttaaattaa attttcgtaa ataagatcta
   108901 ctgccatatc taaattctct aattgatata agtatacttc tttgtagtca atactaatat
   108961 taaactcttt atttaaaata gttaaaaaat tatatgcatt ataatttcca atacatgtaa
   109021 aattgttaaa taaagaatat tcacttacaa attcaaagtc tatttttatt ttagaaaagt
   109081 ttctatttat cacatttatt attttccttg ctatatccaa tcttatcaaa ttagatttat
   109141 aacttggagt gttcaagttt tctattttta aatcttcttt acttttgctt ttttgaataa
   109201 gtatttcttc caattcatta aacttaatat atggattgtt ttttaatata tttgcaacaa
   109261 tgccagttgc cactgcacaa gccttactat ttttaccaaa atgagttact ttatctttaa
   109321 atttaataaa attatctttt gaatttgcat acatttgaat cttattttct ggttcgtata
   109381 tatattgatt atttttatat atattttcat tacctactac accaataaca ctttcaaata
   109441 tagtaggaat actttcttta tcttcatatt tattatgttt tgaacaaata ataaatctac
   109501 cttgactatt taaaatatta caaacctttt ctaattcttt ttcatacata ctattaatag
   109561 atgcagctga aatgtttatt atctgtatat ccgacatagt caacttgctc agtgtactaa
   109621 gaagatttaa agaacttgtt tttccagaat cattaaatat attaatagga taaatttggg
   109681 tatttttact tatatttaat atggttttcg atacaaaagt tccatgtcca tttatgtcat
   109741 ttatttcctt cccccccaaa tctttcaatt gaaaatttga atcataaaca taatttccat
   109801 taatatcatc atcatttaca tctaatcctg tgtctaagac tgctattctt actttagtca
   109861 attaataatc acctctaaaa taaattacct tgaatataaa actaatcctt accataatat
   109921 aggttccaag atgtttttca tttttttaca atttgcatca aacatttttt tgttattttt
   109981 taaagtatat attttcgatg gacaagttgt acaaaataaa tttactttac attctttaca
   110041 actctcaata tttactggtt ttaatttatc aaatatatta aatatatcca tttctctatt
   110101 aagaatcctc tctaatatgt tttcattaaa ttctaatata ttgaatatct ttaaatcctt
   110161 atactctaag tttggacacg gatatacatc tcctttatga tctatactta tctgattaac
   110221 acctgcttta cacatatttg aacataaact actttcatcc acataatcat ctttgcaaat
   110281 gtaatcaata tcaagtttat cattaagata tttgctatag ttctcattac ctctaccaat
   110341 attcataaaa tttcttatta taggcgttgt acctaaatct tcatttaatt tattgaattt
   110401 ctctatgtct ttctcattat tctttcctac caccatagac aaacctacgt tctcgaattt
   110461 ttttagtttt ataagtctaa tcacatttaa tactttacag aatactcctt tacctcttac
   110521 ttcactacaa cttaattcat cataaccatc taaactaatt tctattgcat ataaaccatt
   110581 aattatatca tcaatctgtt tttctttaat taaagttgca tttgtagaca gaattatttt
   110641 acctttaaat ttttctttta tataatccaa cagctctaag aaatcatttc tcatcaatgg
   110701 ctctccacct gtaatggtta atatccttgg atttaattta actatattat ctattacttt
   110761 tcttacttga gatgtatcta aataatcgtt attatctatt ttagaatcta cacagcaata
   110821 atcacaactt agattacatc tattagttgg agaaaatgaa attttgttta ttctctctag
   110881 tctaaattca cttagaatag aatcacttag aagtcctata tgctctaact tatctataac
   110941 tcgttcataa tattttttat cttcattttc ttggaataca tcatacaaat taccaagttg
   111001 taatgcatta tctactgaat actttagaac ttcataacat tctattggaa ttttaaccca
   111061 tcttccattt actttattac taagaataac ttgattatta tttattattt tttcacatat
   111121 acaatctaaa aaatatttgt ttgagctatt catttatttt atttccttcc tatatattta
   111181 aattagaaat ttcattaatt ttctt
//
LOCUS       DAFAZV010000010       106125 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFAZV010000010 DAFAZV010000000
VERSION     DAFAZV010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 106125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106125
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.010"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(294..1895)
                     /locus_tag="KOU88_001107"
     CDS             complement(294..1895)
                     /locus_tag="KOU88_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBK3211010.1"
                     /translation="MIYDLILKNGFIIGGTGNPGFYGDIAIKDNLIAKIDSKINSNTN
                     KEIDCCGKVITPGFIDPHVHEEIVAILDGKFEKFLKQGVTTTINGNCGHSITPYSSEN
                     VYEYMYKNGLLLEEEKKYLIDKNKCWNNFTEYCDLISKSGISVNMGFLLGHGTIRWSV
                     MGGSKDRPPTEKEKNEITDIINDGMKSGAFGISTGLAYIPSKYADIDELVDIARQIKE
                     HDGIYTSHIRDYIGRYNAVKEAIEVGQKSGARVQVSHLSPVEIEAFDEILKARYNGVE
                     IMVDTVPRSSGHCMKKKRVIQFIMAISSSLFELGINGVMDALRNEEGRTLILKEAFIL
                     GDRGSIILLNTKDINMEKKSIREIATQKGIDEDKLLLDLLLDGDEELIFCLGGMYRAD
                     FPDKLHDDKIIDNPFVMVGSDCLFSVGGDMSWFELQRRGAFPIFFNMYRKSGVRLEEI
                     VRRVTSLPARQFKIKNRGILKEGLIADIAVIDMDNYSYSRSEDIDFSKPQLLANGVEY
                     VIVNGKIALENGEITENKCGEVLKR"
     gene            complement(2006..2683)
                     /locus_tag="KOU88_001108"
     CDS             complement(2006..2683)
                     /locus_tag="KOU88_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211011.1"
                     /translation="MSKVKSIYNEEYLPFMIRYGRLTLSLGIIAALVPGIILSFGFGI
                     MPPISALLASTMAIVSMSAPNYIIEPVSYSPILGIPGTYMSFLSGNISNMRLPCSIAA
                     QKAAEVESGTEEGSIISTIGIAVSILVNISILTIGVILGGSVLSKIPAEVVEKLNLIL
                     PALFGSVFGQVFLQDKKLGLVAIVISVLTIILSKQGIIPQSLVVLICVFGTILIARAM
                     YKDKLSD"
     gene            complement(2696..3391)
                     /locus_tag="KOU88_001109"
     CDS             complement(2696..3391)
                     /locus_tag="KOU88_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBK3211012.1"
                     /translation="MDYLKLANHPLLWIASTVAVSIVVVQSLIFAIKSCKVGKTMGIT
                     DKQIKSAVKSSAISAIGPSMTIFAGMVSLIVTMGGPIAWMRLSFIGSVIFESMSAGFG
                     TDALGITLGSPEMTKLAFTNAVWTMILGSLGWIIFTLLFGHKLDKITNVISSGKKSFI
                     PIISLGAMLGSFAYLNADRVLRFDNGTIACISGMAIMVILCMLEKKKNIKWLREWGLT
                     ISMFSGMIIASVI"
     gene            complement(3443..4642)
                     /locus_tag="KOU88_001110"
     CDS             complement(3443..4642)
                     /locus_tag="KOU88_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBK3211013.1"
                     /translation="MKSAYKGYEAYSYLEKGKDISSIEMCKGDKRVKEYLIELDDIQE
                     AKVKSIVDEKIFISLHEHPVLFPEHLERDIFEYNREGKQRCAYEALSRGYYDAIFDNL
                     MDGVCTITSNSGWKWDDILIDLGMRLCDLAHQDFVIKCEKVEDIYRAKSEGKVALIPT
                     LEGAAPIENELDRIDILYGFGIRLMGITYSESNALGSGLKEEKDGGLTNFGKKAVERM
                     NKIGMAIDCSHVGVQTTLDVIEYSKDPIILSHVGARSLWNTKRLTPDEVLIACAKKGG
                     VIGVEAAPHTTITEKNKEHSIESFMEHFEYIKNLVGIDHVAFGPDTVYGDHVKLHSVL
                     AAKFDIKKITGTKEHPKVEYVKGLENPTETSKNIVRYLVKHGYSDEEIEKVLGGNILR
                     VLKQVWK"
     gene            complement(4903..6948)
                     /locus_tag="KOU88_001111"
     CDS             complement(4903..6948)
                     /locus_tag="KOU88_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3211014.1"
                     /translation="MKKHNILFVSTDDKINIDISKQLENIFGEFCNIDNLVYVNRINI
                     ELSSYELVVCSDNDIKEYIHNNIDKNIPIVIVHRTINIENINQIISIENDSDVMVIDA
                     YKESADETAKIIRKLGLIHINLIPYYPGCDKSKCEIGIITGSRNSIPQNIKQIIDIGD
                     KVIDINTVIEIFTKLNISIDKLHIIKEKYNEDTVSGYRYYTTMNKTMKSFLEIIDEGI
                     ASVDKLGKFIYCNKVFSNLVGIDQNEIISNNFMDLFSDKVVKKIFFQEDEVNDEVVNL
                     NNKKLIINKVNVYENNERIKSIISIKNISAIQVLEDKIQNKLQSKGFVSKYTFESVVG
                     ESKIIKEKINIARKIATTDFSVLILGENGTGKEIFAQAIHNESLRKNKPFVAVNLSSL
                     SDTLIESELFGYDEGSFTGAIKGGKMGIFERAHTGTIFLDEIGDISLDVQQRLLRVLQ
                     EKEVMRMGGSKIIPIDVRIIAATNKDLKKKIKEGSFREDLYYRINVLHIEIPRLRERK
                     EDIPLISKYFLDEINSNKCFTEESMQALTLYEWPGNVRELKNLIYYIDTIVEEDRVDY
                     EHLPEQFRFEKNNTLVNENFDSIILDFKQSNFFEESICILTSIETWNNKNILLGRNKL
                     QEILKEKDIVLSVDQIRKRIDKLKSHGLLLSGVKKQGSFITDEGKNFISYVKIKGVI"
     gene            complement(7359..8168)
                     /locus_tag="KOU88_001112"
     CDS             complement(7359..8168)
                     /locus_tag="KOU88_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3211015.1"
                     /translation="MYYVYVNDINIAVYDLNPSAKKTVLFIHGWPLGHKIFEYQTNIL
                     PKLGYRTVSIDLRGFGKSDATSGGYTYSQLADDIYKVVHAIGLKDFTLVGFSMGGAIV
                     LRYMSLFNGYGVSKLVLAAAAAPSFVQRPPEFPYGMTREDVNKLIAQACTDRPEMVTD
                     FGEKVFASNPPESFRRWFNDIGFSASGIGTIGTAVSLRDEELFNDLKCVRVPTGIFHG
                     KLDEICPYEFAVFMNEKIEDSILYTFEYSGHAIFYDELKLFNQEFLQFLEE"
     gene            complement(8252..8785)
                     /locus_tag="KOU88_001113"
     CDS             complement(8252..8785)
                     /locus_tag="KOU88_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBK3211016.1"
                     /translation="MSDAHYDMHKRNGYSSDEPYPEIKVLGPNKYYAELLMDDYAGVS
                     SEFTSVNQYLYHNFDLDETHRELSEMWINISITEMLHMEILAKTIRLLGGNPVYRGST
                     SSCGAYWNGGFVCYGNSICNRLKLDLHLEHVAINNYYKDISLIEDPYIKAILNRIILD
                     EKLHVSLFEKAIEKYCK"
     gene            complement(8935..10284)
                     /locus_tag="KOU88_001114"
     CDS             complement(8935..10284)
                     /locus_tag="KOU88_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBK3211017.1"
                     /translation="MELKNFKDILFKKALSEGFEECEIYYYTGENLSINIYEGEVEKY
                     NLDKSFGLSFRGKVNGKIGYSYTEILDDKAVDMLIKNVKDGVNTIENEDVQFIYEGDK
                     HYNDVKTYSKELENLEADKLIDLALEMERETKAYSDKVVNLSKCTISYSVSSNGISNT
                     KGLNLSNKTNMFIGFVVPIIEDNGQKYDGIGYNIANSIEEIKPCEIAKLGVDNALSKV
                     GGKSIPSGKYKTILLNEAMVSLLSTFSGIFNADSAQKGLSLLKNREGDMIASPIVTIV
                     DDPLLENGMASTPFDDEGVATFKKEVVLNGKLITLLHNLKTANKAGVKTTGNGIKSSY
                     SSPISIYPTNFYIEKGDKSLDEIIKDIDEGLMVTSFAGLHSGANSVTGDFSLAAKGFY
                     IKEGKKVFPVEQITVAGNYFDLLKDIEAIGEDLEFPMSSIGSPSVVIKELSVAGKDE"
     gene            complement(10296..11678)
                     /locus_tag="KOU88_001115"
     CDS             complement(10296..11678)
                     /locus_tag="KOU88_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011967718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TldD/PmbA family protein"
                     /protein_id="HBK3211018.1"
                     /translation="MLSKNIASKVLEKCLITGGDFAEIFEEDTINNSISLIDNKVENA
                     IGGRNYGIGIRIFKGLKSIYAYTSDNSLNSLLDVAYKAAVALGKLEDGKSVILNDSIK
                     INNIHNIKIYPNSIGNRDKVSVMKVAYKSAKEFSNDISQVSVSYLDKDQKILIANTEG
                     IYVEDRRIRTRLGISSIASKGNENQTGFEGPGGCKGFEIFEEIDPEYYAKESARVAHT
                     MLHAKNCPAGNMMVAIDNGFGGVIFHEACGHSLEATSVAKGNSVFADKLGQQIASTKI
                     TAIDDGTIPNYWGSMNIDDEGNPTQKNILIENGILKSYMIDKLNGRRMGMNPTGSSRR
                     QNYKFAPTSRMTNTYIAAGEDKPEDIIKSIPDGLYAKKMGGGSVNPVTGEFNFAVSEG
                     YLIKNGEIQEPVRGASLIGKGSDILMNIDMVGNNVKQAQGMCGSSSGSIPTNVGQPMI
                     RVKEITVGGR"
     gene            11922..13136
                     /locus_tag="KOU88_001116"
     CDS             11922..13136
                     /locus_tag="KOU88_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBK3211019.1"
                     /translation="MNQEYVKGNPIFTNINKVPRQFPYLTDDIDTDVIIVGGGVTGCI
                     CAYYLAKNNIKSVILEKGRIAHGSTSVTTSLLQYELDDNLIDLTEVMTLKDALKAYNL
                     CTSALEELDTFIELYGNKCDYAKRDTLLYTANKLEVKAIKEEYNLRKENGFDVEYIDE
                     STNPFSFDLKSGLIAKNGGRELDPYKYSHHLIDVSLKNGLQVYENTEVKKVDLSNDKV
                     TAEVSYGYKVHGKKLIVATGYNTSLFTKRNFATKSNTFNIATKPLKNIASWKNNILIR
                     DNCDPYNYLRTTKDNRLIIGGEDVSFDDIENETLANEKYDILEQRLKSMFKDIKDIEV
                     EYKYCGCFASTLDNLGFIGPDNKNNNLWYCLGYGANGILFAILGGIMLSELYLGKQNK
                     NMKLFKVDRFDK"
     gene            13313..15226
                     /locus_tag="KOU88_001117"
     CDS             13313..15226
                     /locus_tag="KOU88_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3211020.1"
                     /translation="MKYGGIIMKEILVIAPTKGTYEKSIHIVKKNKYTNIDVVFGNLK
                     EGIPLAEKSINHGTRIIISRGGTYNMLKATYNIPIVEIKVDAYDIIKSYKEVKNSNEP
                     FGIIGFNNVIYGFDIIEEILNKKITMIEIEKEEEIYDAIEKYRKKGINTYIGDTTVAH
                     IVKRLNCKGILIESREENILRAIQQAEQILEATKDEQKRRLQIEAMTDFVHDGIITVD
                     KNFKITLFNKSAEKIFGIKKENALYHNVVDVIPNTVLPQVVETMEPQIGEIQNIGSTK
                     IITNRVPIIVDGQIQGAVSTFQDSKEISSFEHTIRRSLLSKGLSAKYTFNDIIHASEK
                     TKDCIELAKKYACYDTPMIITGESGVGKELFCQSIHNYSKRKNAPFVAVNCAAIPPSL
                     IESEFFGYEEGSFTGARKKGKAGVFELAHEGTIFLDEISEIPLELQGRLLRVLQEKQV
                     MRIGGDKVIPIDVKIICASNKDLKNMMRNGLFRQDLYFRINILTLYLPSLKERKEDII
                     KLSEFFIHKYSSKYNKTPLIITPNIKKALLEREYEGNIRELEGMMERAVIVESFDSIL
                     LEKLSNEYTNNIVDKDNSDFECSNLDLKTLEKKYIYKIYNENNRNTTKTCEILKITRS
                     TLWRKLKEIEDDV"
     gene            15497..16471
                     /locus_tag="KOU88_001118"
     CDS             15497..16471
                     /locus_tag="KOU88_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBK3211021.1"
                     /translation="MHILKSVKKIPGGLMVCPLLFGALFNTVCPQALEIGGFTTSLFK
                     TGAMSILALFCLCNGAQINIRQAGKPLTKGIVLTATKFIIGAVLGIIVSKFIGPKGII
                     GITPLAIVATMTNSNGGLFAALAGEYGDSTDVGAISILSLNDGPFFTMLAFGVTGLAN
                     VPIVALFAALIPILLGFILGNLDEDIREFLAPGTTLLIPFFAFPLGAALNFNQIITAG
                     LPGVVLGLGVTIITGMGGYFVMKLIRAEHPAVGAATGTTAGNAAGTPEALAAIDPTLA
                     TIAAVSTVQVAAAIIVTAICCPMLVSYLDKREKKKKSIFKTNKNIEVN"
     gene            16492..16767
                     /locus_tag="KOU88_001119"
     CDS             16492..16767
                     /locus_tag="KOU88_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBK3211022.1"
                     /translation="MNAIIHANEKDNLVTCVRPLVKGEKVSIDGKSYIVNDNIPVFHK
                     MATEDVKKGDVVYKYGEIIGIATVDIKTGDYVHVHNIESTRGRGDKK"
     gene            16780..17943
                     /locus_tag="KOU88_001120"
     CDS             16780..17943
                     /locus_tag="KOU88_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBK3211023.1"
                     /translation="MKLMGYLRENGQFGIRNHVLIIPTSVCSSETATRIASLVPGAIA
                     IPHQHGCCQIGSDIELTAKTLIGFGKNPNVAAVLVVGLGCDGIQAKELASEIATTGKK
                     VDYIVIQECGGTLKTVSKGAEIVSKMAREVSKEVRVEFGMSEITLALECGGSDPTSGI
                     ASNPSIGVASNLLVDEGGSSILSETTEVIGAEHLLATRFEDEEMKDKFLKFVSDVEKR
                     AIAMGEDLRSGQPTPGNKTGGLSTIEEKSLGCMYKAGNKPFKGALEYADIVPPDKKGL
                     YFMDTPGQDIDSITGMVAGGAQIVIFSTGRGTPTGSPISPVIKITGNSDTYNKMPDNI
                     DINAGRIITDGAKIADIGQEIFNEIIEVCNGKHTKAESLGHREFGIYRISSTF"
     gene            18280..20559
                     /locus_tag="KOU88_001121"
     CDS             18280..20559
                     /locus_tag="KOU88_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3211024.1"
                     /translation="MNFENTKNKKIIATLLLTLLLIVSLTCVTFIMNLNKVTHNETER
                     YLVEVSQGISTTINVKCKSIFRTLYSMGDTYFEINDSEKEVNRYLSKKLKLFEFDWLG
                     IIDSNGNFVSALKDTGNVKGQDFYRKALQGKETITPVKSQSGTYGILYSVPLYNGDKI
                     VGAVAAWNTIDTMRNLLSVESFHGEGFSQIIDQDGNFIVSSANKNAPKNVVNFFDMIK
                     HQGKQVDKNKLEEMKINLKKNKTGSMYYTLNDGISKAMHYLPLQEENLYLLSIVPTKT
                     ASAQFDLLLKKAIFINILIVILFLLLIILIMFINQKNRAQLIKIAYVDSVTKGYSKAR
                     FDIEAKKIIQSSSSESYSLVSINIQKFKLINDSFGSEAGDKTLKYIHDVISNYLEPGE
                     LLCRVSNDQFNVLIKTIPQKEILKYIENITNDINSFNKNEECKYFIALSIGVYKIDDP
                     NLPLVSIQDRANVARKNNKGNIGNHPLYTCVFYSDLERLKMIKEKEMENRMEEALNNN
                     EFIVYLQPKISLKDNTIVGAEALVRWQDPNKGLIPPDEFIPFFEKNGFITKLDHYVFE
                     KVCSMIRKWIDNGETPIPVSVNFSRANLNNIDFLEKYRMLRNKYNIPAKLLEIELTET
                     LVFENLQKLINIIDQIHEEGFQCSLDDFGSGYSSLNMLKEIKVDTLKLDRAFFSSPNA
                     DNIAENHVIESIVNLAKKLNMNSISEGVETILQMDYLKKINCDMIQGYVFSKPLPQEI
                     FEKMTFGKKLEETSMDSSV"
     gene            complement(20654..21994)
                     /locus_tag="KOU88_001122"
     CDS             complement(20654..21994)
                     /locus_tag="KOU88_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3211025.1"
                     /translation="MENQEALRHEKIWILLFRYSIPAIIAMMVTSLYNVVDRAFIGSM
                     EGIGSIAIAGLGVTMPVFTLIIAFGMLVSVGASTRLSIKLGERNREEAEKILGNALTL
                     SIIISLIITILGLVFLEDILFILGASKDSIFYAKDYMSVILVGSIFNLVAFSLNNAIR
                     AEGNPKLAARTMIVGCVLNLILDPIFIFVFNLGIKGAAIATVLCQIVVFFWVIHYFIR
                     GKSNLKLKKCNLKLNKDIVKKVFAIGMTPFAMEVAISITHMFTNNSLKVYGGDLAIGA
                     MTALTSILLMFMMPVFGLNQGMQTIISYNYGAKQYERAKKTLILSIIVSVVILSFGFL
                     VVQVFPEVFVGIFNKDSDLMDIAVRGISLNLITLPIMGISIVGPVYFQCISKVKHSMF
                     LTLLRQFILFIPLIIVLPIQFNLDGVWLAQPVADFIAMIIVLLFLKREFKTSRV"
     gene            complement(22006..22788)
                     /locus_tag="KOU88_001123"
     CDS             complement(22006..22788)
                     /locus_tag="KOU88_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004460318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211026.1"
                     /translation="MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKST
                     ILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMAVLPQSPQAPSGLTVSELISYGR
                     FPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
                     LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKI
                     VCEGDAYDVMTKDNLKELFNIDAEIATDPRTNKPICITYDMV"
     gene            complement(22803..23825)
                     /locus_tag="KOU88_001124"
     CDS             complement(22803..23825)
                     /locus_tag="KOU88_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBK3211027.1"
                     /translation="MKNIIKINSKTLLVISILMVLIFITFLLSLNMGSFSIEPMDVIK
                     TFLGQGERNHEIAIFKLRLPRIVIALLVGSALSTAGVILQGVTKNDLADSGILGINSG
                     AALFVVVYIYLMNGNVYEGMSNLTVFTMPIVALIGALFGAFLIYSLAWKGGINSSRLL
                     LIGIGVNIAFTSILTIFQLKFTTQEFNRVMAWTSGSIWGTSWKYVIAVLPFIVIFMGI
                     TIYKSKYIDVLNLGDEVSISLGVDVEKQRRRLIIYAVILSGVSTAVAGSISFLGLIAP
                     HIGRKIIGPKHKRLIPVSALIGTLLLLIADTISRNLLAPIEIPVGIVVSIIGVPYFIY
                     LMLVND"
     gene            complement(23831..24844)
                     /locus_tag="KOU88_001125"
     CDS             complement(23831..24844)
                     /locus_tag="KOU88_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBK3211028.1"
                     /translation="MTKLSKKNITYLLILVSIVVLVFGIVLSITIGAKDMNLSTVIDS
                     LIKMEDGINMRIVKDVRLPRAIAAALVGGFLAVSGAIMQGITRNPIAEPSVIGITQGA
                     TFAISISLVLQKKLPQLIHGSFSVMMFAFIGASISGLFIYFISSKSRGRVNNVKLALA
                     GVALGTLLISLASAISMYFNLSQQLSFWISGGLVGVKWEGIKLLFVAGGIGFILAIIM
                     APRITILSLGEEVAIGLGQKTNFVRFICIVLVILMTGASVSVSGNIIFIGLIVPQIAK
                     GIVGSDYKYIIPSSLVLGAVLLVYTDILSRMINPPYETPVGSITALIGVPIFIYLVRK
                     GEK"
     gene            complement(24972..25910)
                     /locus_tag="KOU88_001126"
     CDS             complement(24972..25910)
                     /locus_tag="KOU88_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3211029.1"
                     /translation="MKKIKSLAIFISIITTLVLVTACSDKNTEDKDKSETRVVQSVKG
                     EVKIPSNPKKIVDISGSSEELLLAGYKPVATANVDSYETDKLPSYIREELKGVKIVGH
                     SMMDTMDMEAILEVNPDLIIMSQRQEKIYDQLKEIAPVVMMKDYANDWRSKLTDVSKL
                     FDKEEEAKSWLQKYDEKATKLGKEVIEKNGEKTYLPVLASSGQFMVFSDGGIGTLIND
                     DMKLARPKNMPKQDGITLPMVSMEGLTDIDADHIVVIATEADKKDLENSAIWAQIRAV
                     KDGNVTILDAAPFFSQSYNPIGKELLLESVKNELTK"
     gene            26180..26644
                     /locus_tag="KOU88_001127"
     CDS             26180..26644
                     /locus_tag="KOU88_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016208838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211030.1"
                     /translation="MVHLVYCDNAGKKGEKVLDKILAGTKTMVIRGAAGRKIPHSRVF
                     EDELLYFMEKGTAKISAKATVKKVENYVKLTEDEISKILNENQPKLNLSEKQKVRWHK
                     KCLCLVEFENVEEITPLDFDHQGNMDDWLIVEKIEDVVVGTSIPYNYEKSKF"
     gene            complement(26756..27073)
                     /locus_tag="KOU88_001128"
     CDS             complement(26756..27073)
                     /locus_tag="KOU88_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK3211031.1"
                     /translation="MDEKMIEISFGIIGFAGDAKGLAFEAIKEAKSGNIDKARECIEK
                     SKESIHKAHKFQTELIQNEANGNKTEISVILIHAQDHLMTAMNFQQLAEEFIDVYERL
                     ESK"
     gene            complement(27086..27817)
                     /gene="chbG"
                     /locus_tag="KOU88_001129"
     CDS             complement(27086..27817)
                     /gene="chbG"
                     /locus_tag="KOU88_001129"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBK3211032.1"
                     /translation="MTKIIINADDFGYCEAVNYGIISAHNNGIVRSTSMMANMPGVEH
                     GVGLLKENKTLNCGVHMTLSCGRPLLSNLKTIVDKDGFFIRRITDEIIEKMDCDEIYR
                     ELCAQIDRVKGLGIDISHLDSHHHIHTLVSLKSVIEKIVTKYNLPIRGGFEYNLEYSK
                     VVPLIDSFYKENVSEEYFIKNIDEIMKYDVVDIMSHPAFLDDYILNSTSYAIDRTKEH
                     KILTSKKVKEFLEKNGLVISSYRDI"
     gene            complement(27843..29153)
                     /locus_tag="KOU88_001130"
     CDS             complement(27843..29153)
                     /locus_tag="KOU88_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK3211033.1"
                     /translation="MKKGLKIVTIGGGSSYTPELVEGFINRYEELPVKELWLVDIEAG
                     KEKLEIVGNLAKRMVKKAGVDMKINLTLDRREALRDADFVTTQLRVGLLDARIKDETI
                     PLSHGVMGQETNGAGGLFKALRTIPVIFDIIKDVEELCPNAWMVNFTNPTGIITEAVF
                     KYTNFRRYIGLCNVPIHLKNDVAKLFNVESDRISMDFAGLNHMVYGLNVSLDGEDVTK
                     EAIDKFVKADISMQNIKAIDFNAEFVKSLGAIPCPYHRYYYKTKEMLEDELREFKEGK
                     ARGQVVKELEEQLFELYKDEKLDVKPPQLEKRGGAYYSDAACNLISSIYNDKKDIQVV
                     NTLNKGSIRDFKDEQAVEVSSVITKNGPKPISIGYLPDSVHGLVSQIKSFEVLAAKAA
                     VYGDYESALLALCINPLIPSDDLAKTILDEMLEAHKDYLPRFNR"
     gene            complement(29230..30543)
                     /locus_tag="KOU88_001131"
     CDS             complement(29230..30543)
                     /locus_tag="KOU88_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3211034.1"
                     /translation="MEKFMSFMDKYIVPVAAKIGAQRHLVAVRDAFIVMIPITMVGAL
                     GTLINNLPLEAYKNLMASIFGENWTTFGGDLWWGAIGTMAVFLVIGVAYFLAKSYESD
                     GLQSGLIALSIFFIMAPQIGKIVPEGGTTVVEGWGMIQQTYLGTAALFSSILIGLLST
                     EIFVRLSKVKKLTIKMPDGVPPAVSRSFAKLIPGMLTIMIFTVIGIFIKMLSNGSFLT
                     DILNTYLGAPLSNVADSLGSTMLIAFIIHILWTVGLHGANIALPFTETILMKLGGENA
                     ALAQAGATEGYHVLAGAFFDAFVYLGGSGMVLGLIVALLIAGRRRKEMIVLGGPPAIF
                     NIGEPLIFGLPIVLNPIFMIPFVLAPVICSAVSYLAIDFGLVAPVILPKIPWVTPPIL
                     GGAMATGDWTGGALALFNLILSILIYIPFVIASEKMEANKLKINN"
     gene            complement(30565..30876)
                     /locus_tag="KOU88_001132"
     CDS             complement(30565..30876)
                     /locus_tag="KOU88_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3211035.1"
                     /translation="MIKIMLACSAGMSTSLLVTKMEDAAKENGIEAKIWAISEVNLKN
                     EIENCDVLLLGPQVRYVLGKATEMAKPYNIPVEVINMMDYGRCNGKAVLDRAVELNSS
                     K"
     gene            complement(31076..31780)
                     /locus_tag="KOU88_001133"
     CDS             complement(31076..31780)
                     /locus_tag="KOU88_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3211036.1"
                     /translation="MKEPIYKVIENHVRELINSDSLKEGDLIPSEKQLSEEFNVTRMT
                     VRSALNNLVKEGYITRQRGVGSIVIANNIYDNISSVSGFTKEMESKGYKVSNILVSLE
                     IVQADENLSSKLNISLEENVWEIKRVRLANDARVSYMITYMPVKLFPNLNKTHCENSL
                     YNFVEEVCGYKIAMSEREVQAVISNEECMDNLKLEEPEPLLYISQICKLQNSEIFEYS
                     HTYHYGYTLTLNAVVE"
     gene            complement(31871..33232)
                     /locus_tag="KOU88_001134"
     CDS             complement(31871..33232)
                     /locus_tag="KOU88_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3211037.1"
                     /translation="MKDRLNLTEGRITEKLLKLSLPIMGTSFIQMGYNMIDMIWVGKA
                     GSKAVAAVGTAGFFPWLAMAFIMISKVGGEIKVAQSIGANNISTTKSYMKSAIEINII
                     LAIIYTISLIVLNKQLIGFFRLGDLEVITMSRQYLIIVALGMVFYFINPVFTAIFNGL
                     GNSKTPFRINTVGLITNIILDPILIFGWGFAPKLGVAGAAIATVFAQIVVTTCFIYII
                     VKSKEEYFKLRLFKEIETKYYKVLYKLGLPIAIQSGMFTVFSMLLGVIVASWGPVAVA
                     VQKVGSQIEAISWMTAEGLSVALGSFVGQNYGAKKYSRINKGCKIAITVSSVLGIITT
                     LVLVFAGESIFSIFIDESEAIEKGAIYLKILGYSQFFMCLEIITTGAFKGLGRTYIPS
                     IIITILTGARVPLAYFISRPEMLGLNGVWWSITLSSILKGILMISLFISLLKLGKLYK
                     ISE"
     gene            33731..34885
                     /locus_tag="KOU88_001135"
     CDS             33731..34885
                     /locus_tag="KOU88_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3211038.1"
                     /translation="MKINKKFNRVDMQVSILTAIIVIISSSCVYFFNYTLTYKSMIYS
                     LSERSKHIYEYVERNIDKNTFTEINSKEDQSKKSYKSSKILLESVKNTTGVMYLYTAK
                     KTKDGSLVYVVDGLNSSRSDFRSAGDLIEKEIWGDLNKALDNHILLPKKIKSTSWGYI
                     FISYFPIHNDVGKVVGVIGIEFEAKHQYNTFKFISIVTPIIALLTCLISALIAVILFK
                     RISNPTYTDFANTDYLTGLKNRNAFEIDMNNLNNSNLKNLISIISIDLDGLKKINDKF
                     GHQTGDLYIKQASKIIQYVINKKYIVYRIGGDEYIIILKNLSHKEINNIINNINLKIV
                     EENSTNELKLSMSIGYAIFDEKVDVSLFDTYRRADSQMYDNKRKINKQYQ"
     gene            complement(34967..36685)
                     /locus_tag="KOU88_001136"
     CDS             complement(34967..36685)
                     /locus_tag="KOU88_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     permease subunit"
                     /protein_id="HBK3211039.1"
                     /translation="MNNNAISSKSISLKSKMNLDIKKCMLTVLVMSLVIFLLAPIIYL
                     FVQAFLDKDGVFVGLQNFQEYLASESLLNSLKNTVFVSVISTVISLTLALVYAYALTR
                     TKIKFKGFFKSLAMFPMFAPTMMHAIGLVYLFGNQGLVTNLLGVHVPIYGAVGIILAQ
                     IIYVFPQSFQILYISLSSTDYRLYEASNTMGISKIREFISITIPSIKYSLISSAFVSF
                     TLCFTDFGAPKVIGGEFNVLSIDVYKQIIGQQNMPMGATVSILLLIPAIISFIVTKKI
                     EKNQNSYITSKSIPYKVKTNKLRDSILGGVVGIIAFGIIAVMLTVILSSLISVWPYDL
                     RLTLEHFSMKNSIDGIKPFINSIKMSLLTAILGTSFVFLFAYLNEKTEKAPYLKSFGY
                     FLSTLPMALPGLVLGIAYVLFFNKLEFNFMDTIYIKNLFNGLYGTLLIMVICNIVHFF
                     SVAFITATTAIKKVDKELDMVAKSMGINSASILKNVTIPLCLPAVLENFMYFFLNSMV
                     TISALVFIYTASSKVAAISIVQLDDKGSTAQAAALAVLILVTNILVKVIYEFIKNRLE
                     KRTNFN"
     gene            complement(36690..37679)
                     /locus_tag="KOU88_001137"
     CDS             complement(36690..37679)
                     /locus_tag="KOU88_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3211040.1"
                     /translation="MSYLKINNVFKSYDQKRVLNNISLDIEEGEFLCLLGPSGCGKTT
                     LLRIIAGLEDVNSGTIILQDKDITNLEPSKRGFGIVFQSYALFPNMTAYNNIAFPLKE
                     RKVSKEKIDNKVKEVLETVGLTNEAHKYPKALSGGQQQRIAIARALALEPKFLLLDEP
                     MSALDAKVRHKLRMDIKRLQKELNITTIMVTHDQEEAITMADKIAILNGGDIMQIGTP
                     EEIYQNPQNLFTAQFIGDTNCFDNGDSILTVRPEYVQIEKSTKENYQGIISNIEFRGN
                     LLRVEIKDKLNENFIISDVSIKEWVNLNLVEGDLVKISIDEKYYLKYPKVKGA"
     gene            complement(37775..38824)
                     /locus_tag="KOU88_001138"
     CDS             complement(37775..38824)
                     /locus_tag="KOU88_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative 2-aminoethylphosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK3211041.1"
                     /translation="MKEFIFTCLCIVVITFMTSCISTTPQTTQGKGNNKLTIYAALEE
                     EQIAYYMEGFREEYPNIDVEIVMDSHGVIASKLLAEKDNPQADIIWGLSAMNMIELKK
                     DGALEAYKPKNYDKVDKKFKDTEDDVSWVGMSVPETAIVVNYKELKKLGIDIPKSYED
                     LIKPEYKGLITMPNPASSGTGYLTVSGLIQMMGEKDAYNYMDKLHKNIATYTHSGSKP
                     AKLAGSGEYPIGITLGYRATQQLSSGEPIEVVFPKEGSGWDLEANALVKKDNIKKEAK
                     LFLDWAISDSAMDRYAHEVAVTSIKTDNPVPKGYSKQPFEQLIKEVDLNSAAKNRSTV
                     LKTWESKYGSKSESK"
     gene            complement(39102..39770)
                     /locus_tag="KOU88_001139"
     CDS             complement(39102..39770)
                     /locus_tag="KOU88_001139"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBK3211042.1"
                     /translation="MARLNINPTRMEMTRLKKLLKTATRGHKLLKDKLDELMKQFLEI
                     VRENKRLREEAENALDTAYKNFIIARAVMSQEYLGSALMMPKQSVSVDVSTRNIMSVD
                     VPVFDFKTENNQSDIYPYGLAFTSGELDSAMEAFSDAMQPLLRLAESEKSAQLLAQEI
                     EKTRRRVNALENVMIPNYIETIKYIAMKLEENERASTTRLMKVKDMVLKKALEEKKKN
                     DLVV"
     gene            complement(39776..41149)
                     /locus_tag="KOU88_001140"
     CDS             complement(39776..41149)
                     /locus_tag="KOU88_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBK3211043.1"
                     /translation="MIKEYKSIQEVAGPLMLINGVEGVKFDELGEIELSNGEIRRCKV
                     LEVNGDTALVQLFESSTGINLAESKVRFLGKSLDFGVSPDILGRVFSGMGRPIDGGPE
                     IIPDKRLDINGAPINPAARDYPAEFIQTGVSAIDGLNTLVRGQKLPIFSGSGLPHANL
                     AVQIARQAKVRGTDSKFAVVFAAVGITFEDAEFFISDFKATGAIDRSVVFVNLANDPA
                     VERVSTPRMALTAAEYLAFEQDMHVLVIITDITNYAEALREVSAAKKEVPGRRGYPGY
                     LYTDLATMYERAGKMKGHEGSITMIPILTMPEDDKTHPIPDLTGYITEGQIILSRELY
                     KKDIQPPIDVLPSLSRLKDKGIGKGKTREDHADTMNQLFAAYSRGKDAKELMAILGES
                     ALSEIDLMYAKFADEFEKEYVSQGFRTDRTIEQTLEIGWKLLSMLPKSELKRIRDEYF
                     EKYMPKE"
     gene            complement(41146..42924)
                     /locus_tag="KOU88_001141"
     CDS             complement(41146..42924)
                     /locus_tag="KOU88_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBK3211044.1"
                     /translation="MKTGTIVKVSGPLVVAEGMRDANMFDVVRVSDKHLIGEIIEIHG
                     DKASIQVYEETSGLGPGEEVVSLGMPMSVELGPGLISTIYDGIQRPLEKMYDISGTNI
                     TKGVEVSSLDRTTKWEFKPKKSVGDKVVAGDIIGGVQETAVVECKIMVPYGVKGTIKE
                     IYSGEFTVEDTVCVITDEKGNDIPVTMMQKWPVRKERPYREKKTPDSLLVTGQRVIDT
                     FFPITKGGVAAIPGPFGSGKTVTQHQLAKWADADIVVYIGCGERGNEMTDVLLEFPEL
                     KDPRTGESLMQRTVLIANTSDMPVAAREASIYTGITIAEYFRDMGYSVALMADSTSRW
                     AEALREMSGRLEEMPGEEGYPAYLGSRLAQFYERAGKVNCLGMDEREGTLTAIGAVSP
                     PGGDTSEPVSQATLRIVKVFWGLDASLAYKRHFPAINWLTSYSLYQEKVDVWADKNVN
                     DNFSAQRAQAMKLLQVESELQEIVQLVGVDSLSDGDRLILEVTRSIREDFLHQNSFHE
                     VDTYTSLHKQYRMMGLILKFYKSAQDAIKQNVTINDIIKLSVLEKIGRAKYVEEGDID
                     AAYDSIEDEIDNELADLIKKRGAEEL"
     gene            complement(43041..43364)
                     /locus_tag="KOU88_001142"
     CDS             complement(43041..43364)
                     /locus_tag="KOU88_001142"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBK3211045.1"
                     /translation="MLMYKVGVVGDKDSIMGFLALGIDIFPAYDSDEIKKSIHKLVED
                     EYAIIYITEQASLLAKESIAKYKDYQLPAIIVIPGIGGSMGLGMNEVRESSKRAIGAD
                     ILFKE"
     gene            complement(43351..44328)
                     /locus_tag="KOU88_001143"
     CDS             complement(43351..44328)
                     /locus_tag="KOU88_001143"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit C"
                     /protein_id="HBK3211046.1"
                     /translation="MAEEKTYPYAVARIRVLEKQLLNRQMFIQMAEAKSPEDSLRIIA
                     EAGYADTSNNNIHNFENILTQELSKTYEILKSLAPEEKFVDVFLYKNDYHNLKVLIKE
                     EISGVDGEKYLIDGGTIPLIKLRESLANRSFSDLPKIMSSAILEAFDVYNKTQNGQMV
                     DIVLDKATFTSMKETAKESQNKFVIDYVMKVCDLTNLKSFIRVKNMKKDFDMFMNVFV
                     SGGSLDKEKFLEAFSSDTPASCFKSTSYSDVCKNGMDSGFTVFEKLCDDYLMEYVRGA
                     KFKPLTLEPLIAYLYAKESEIKTIRIILTSKLNNIDADTIKERLRDAYV"
     gene            complement(44343..44906)
                     /locus_tag="KOU88_001144"
     CDS             complement(44343..44906)
                     /locus_tag="KOU88_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit E"
                     /protein_id="HBK3211047.1"
                     /translation="MGNEQKMIDRIIADAKQEAQEILDKAKSEADLKVNSANEKAEKE
                     MASYTKLAEAEAEKAASKEISGAYMEAKKQILSKKQEILEEVILEAKNKLLNLKDNEY
                     EEIILNMIEKSNCTDDSEIVLSKKDKKTLKDVLSKKGIKVSDETRDITGGFIVKKGDI
                     EYNYSFEAIIAVEHEYIEQIAAEILFN"
     gene            complement(44958..45449)
                     /locus_tag="KOU88_001145"
     CDS             complement(44958..45449)
                     /locus_tag="KOU88_001145"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBK3211048.1"
                     /translation="MEFLNALGNGQFLAISGAAIAALFAGMGSAKGTSIAGQAAAGVV
                     TEDPSKFGQLLVLQLLPGTQGLYGFIIAFLILSKAGIIGGDAIPTSAQGLQLLMAGLP
                     IGLVGLVSGIAQGKAAAAGVGIVAKRPEELGKAITFAAIVETYALLGLLVSFLAYNGI
                     AIG"
     gene            complement(45452..47377)
                     /locus_tag="KOU88_001146"
     CDS             complement(45452..47377)
                     /locus_tag="KOU88_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBK3211049.1"
                     /translation="MAIVNMNKISIVGLEAQKSQILKLLMNRGFVQIDDSAFLTEEEE
                     LKNYLVKDSEESEVIMLEQKMSHVNQAINIVSSLVKQKKSLLAPKREFNKIDSEKEGQ
                     VYAEALELNNLHKEIGTIRSNINLLNNNKSMLEPWVNFDIPIENMETKYTKTILGTVP
                     ISANIDALRVKLEDEIPESVIGIVNSDKLMNYVYLITLKETFDDVLEVLKEFNFSVVS
                     LPNEEGTPLQAIKKYNEMIIRQENVSKDKTEEIKRHADSIHMLENLYDFYTIERDQKK
                     IIERLVKTKTTFCLNGWLPSKRADELIKEITEKFDCCVQTEEGSKEEGFPILLENNKL
                     VTPFESVTNMYSYPSTKDIDPNTILTFFFVVFFGMMLSDAAYGLIIAVVCGFVVYKLK
                     IQKGEGNLIKLIGICGVSTTVWGLIFGGILGDLIPIKALINPLEDVMTLMGMSLLFGI
                     IHIYVGLGIKAYTLIRSGKVIDAIFDIGFWYLCITGVCLLIIPFVAGDIGVFSEVGKY
                     LAIIGAIGLVLTQGRSFKGIPVKLFKGFSSLYGITSYFADILSYTRIMALCLTTGVIA
                     QVINLLGAIAGPILAVVIGVVGHTINLLINALGAYVHTSRLQYVEFFNKFYEGGGVPF
                     VPFKYKTKYTSINKKEM"
     gene            complement(47379..47690)
                     /locus_tag="KOU88_001147"
     CDS             complement(47379..47690)
                     /locus_tag="KOU88_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211050.1"
                     /translation="MAFEIIKSIVEAEQTADSIKVKAVTDAESIRADAVNKCESIFAD
                     VKKQAKLMEETLIEKAVTDSRAEVDKILANAKSECLKIEKTAEERKSKAIEAVIGKVV
                     R"
     gene            complement(48320..48595)
                     /locus_tag="KOU88_001148"
     CDS             complement(48320..48595)
                     /locus_tag="KOU88_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif11-like leader peptide family natural product
                     precursor"
                     /protein_id="HBK3211051.1"
                     /translation="MNEKLTKILEEAKNDDEFRKELIKTREQRDVMDSFCKVVTSRGY
                     DMTVGELFSMGEEYTSNLLKSVNGGAAYPIEDWSDWYEDFFIMLSNI"
     gene            complement(48710..50119)
                     /locus_tag="KOU88_001149"
     CDS             complement(48710..50119)
                     /locus_tag="KOU88_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBK3211052.1"
                     /translation="MIDGKEVKQESGQKNLKFKIAIVVGVLFVAYIGMAIFFRNHFYF
                     GTTINGVKASGKTVEQVNDLLASSTNSYTLNLEERNNKKEQIKAKDIDLKFTPDDKVQ
                     KIKDSQSAIGWIGGIFKSKEYNNMITLSYNKDLLEKRFNALSCFDSKNVVEPKSAYPK
                     YDSTKNAYVIVPEVLGNKVKKDDFYKLVQNSINSGNTSISLDESKVYEAPNNTKDSEK
                     LKQAIKTLDKYVGVVVTYDFSDRKETLDGSEINKWLKVDSEKNYDITFDNDAMVEYTR
                     GLSKKYSTFGDSRPFKTATGKDITISGGIYGWLIDKKKEAEALVDVVKAGKNVTREPI
                     YIQKAVSRNKDDIGNTYVEISLSGQHMWFFKNGEMLVSTDVVTGDLARGFATPSGIYP
                     LNYKARNVSLTGQGYSSPVSYWLPFNGNIGIHDATWRNSFGGSIYKSSGSHGCVNTPF
                     SKAKKIYENIEPGTPIILY"
     gene            complement(50490..51152)
                     /locus_tag="KOU88_001150"
     CDS             complement(50490..51152)
                     /locus_tag="KOU88_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211053.1"
                     /translation="MIDVSIDDKLKERWPNAKLGCIQAKVAVNKSSEKLINEINEFCD
                     TINQSLKVEDITKLDKIKDARNAYKELGKNPSRYRTSSEALVRRIIQGKGLYTINNIV
                     EINNLISIKSLYPVGTYNVSKLHSPVCFTVGDEGEQYKGIGKELINIENLPILSDSVG
                     KFGSPTSDSERAMITEDANEILICIFSFSQESDIEEYFGYAKELLKEYADGKDIETKI
                     IK"
     gene            complement(51406..53625)
                     /locus_tag="KOU88_001151"
     CDS             complement(51406..53625)
                     /locus_tag="KOU88_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3211054.1"
                     /translation="MTGRNKSFTLITILFLTSLFLTMGYIYIEDTKHLLMSEAKIHIK
                     EVAVQGSQLAQRQIEKDLDVLNIFSNYYASNPDIPNEEKMKNLLNEMENQKFYTMAIV
                     DINGNAENTKGDKFSVKDREFFKNSIKGKKYVSSPYVDEVNKSIKKIAISVPLLNNDK
                     VVGVLYCTYNINTLMKLINISFYENNSISYVVKNDGTIILHPQGDSLSKNIYKLLEQD
                     NDIQEVNRLKKELQENKTGATVLNMLEERRYLGYATMDNGNSENNYIKDWNLIFSIPE
                     TVVFSNSKQIINRAVYAVLSIVLIFVAIIFYIIYIKKSNEKEILSLAYEDKVTYIGNQ
                     NKFYRECSKYLLDKPSLNYIIVYFDINNFKMINDTFGYEFGDNLLITIAKALKEELTE
                     GEVYARLSSDYFAIFCDYKNGRNKIIRKLDNIRSNIESNLSIVFEISLCVGIYFVEEG
                     EVDIQKAVNKANMARSVAKGKNINYAIYNEDVRNKLSEESMILDDIKIALVKNQFEVY
                     YQPKFSLVTGEMIGSEALIRWNHPEHGFISPAVFIPIAEKSKLILKIGRFVFERVCND
                     LSEWKKQGKKIVPVSVNLSRVELYQPDIVKFINKTIQMYNLSSDFIEIEITETVAINE
                     LNILKNVLNELRKHGFSISMDDFGTGYSSISCLRDMPIDILKLDKSFLGGIEHDERSR
                     NIAKSIVSLAKSLDLVVIIEGVESKEQAELMKQFGCDLVQGFYFARPMPAKNFLDLL"
     gene            complement(53901..56555)
                     /gene="adhE"
                     /locus_tag="KOU88_001152"
                     /gene_synonym="adhC"
     CDS             complement(53901..56555)
                     /gene="adhE"
                     /locus_tag="KOU88_001152"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBK3211055.1"
                     /translation="MAHKEQVIIENKKQNEVMSVGLDTVNNVESLVKKLAKIREAQKI
                     FATYSQEQVDKIFLAASLAANKQRVPLAIMAQKETGMGIAEDKVIKNHYASEYIYNAY
                     KETKTCGVIEKDEAFGMTKIAEPIGVIAAVVPTTNPTSTAIFKALLALKTRNGIIFSP
                     HPRAKNSTIEAAKVVLEAAVLAGAPEGIIGWIDEPSLELTTTVMKEVDLTLATGGPGM
                     VKSAYSSGKPAIGVGAGNTPAIIDDSADIKTAVNSILVSKTFDNGMICASEQSVIVLE
                     NIYNEVKKEFKERGAYLLDKDETEKIRNIILVNGGLNSKIVGQTACTIAKLAGFEVPV
                     DTKVLIGEVESVEIEEAFAHEKLSPVLAMYKASDFDDAVRKAEKLVEDGGFGHTSSLY
                     IDDVNQREKLDKFTSAMKTCRILINTPSSQGGIGDLYNFKLAPSLTLGCGSWGGNSVS
                     ENVGVKHLLNIKTVAERRENMLWFRAPEKVYFKKGCLGVALKELKDVMNKKRAFIVTD
                     TFLYNNGYTKAVTDLLDEMNIKHTTFFEVEPDPTLECAKIGAKAMREFNPDVIISIGG
                     GSAMDAGKIMWTLYEHPDVDFQDLAMRFMDIRKRVYTFPKMGEKANFVAIPTSAGTGS
                     EVTPFAVITDQDTGVKYPLADYELMPNMAIVDSDMMMNMPKSLTSASGIDALTHALEA
                     YVSMLATDYTNGLALQAIKSIFEYLPRAYDNGAKDPEAREKMANASTMAGMAFANAFL
                     GVCHSMAHKLGAFHHVPHGVANALLITEVMKFNSSDAPKKMGAFSQYKYPEALKRYAE
                     IASFLGLKGNSDEEKFQSLLVAIEDLKLKVGIPKSIKEFGVEESKFMDSIDEMVIQAF
                     DDQCTGANPRYPLMNEIKDMYLNSYYGR"
     gene            57059..57259
                     /locus_tag="KOU88_001153"
     CDS             57059..57259
                     /locus_tag="KOU88_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211056.1"
                     /translation="MKKLKTISIFSLIISVILTIGGIGIVTYYVDNLFIRGLSVFVLI
                     MSSSFVSTTVRLIFEESKRYKF"
     gene            complement(57466..58056)
                     /locus_tag="KOU88_001154"
     CDS             complement(57466..58056)
                     /locus_tag="KOU88_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit B"
                     /protein_id="HBK3211057.1"
                     /translation="MRLEGLTIGVGFTGSFCTYDKIFIELENLVKEGANVHTIFSDVS
                     QNIDCRFGNSEEFMKKAYELTGNKPIVTIEEAEPFGPKGIADIIIIAPCTGNTAAKLA
                     NGITDSPVLMAAKGHLRNDKPLVISISTNDALSFNFKNIGILLNSKNIYFVPFGQDNC
                     KAKPNSMIAHTELIIPTIELALENKQLQPVIKSPHQ"
     gene            complement(58059..58934)
                     /gene="dpsA"
                     /locus_tag="KOU88_001155"
     CDS             complement(58059..58934)
                     /gene="dpsA"
                     /locus_tag="KOU88_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipicolinate synthase subunit DpsA"
                     /protein_id="HBK3211058.1"
                     /translation="MSNQYDITVIGGDLRQMYMVKKLINKGYSVVTYGISNEIINGIV
                     GKSTSLAEALSKSSIILCPIPFTKNQVNIENTDDCLDATIDNLLINLSPNQILFGGNI
                     STKVCKFCEQHSIQIYDFMKMNDVAILNAVATAEGAIAEAIKRSIINIHQSNCLVLGY
                     GRCAQILAKKLYALDANVCVGARNNDARSTANAFGYSSISLSQLDEKLLQFDYIFNTI
                     PECILTKERLEKVSQEVTIIDIASSPGGVDYSVVKEAGINATLCLGLPGKYSPKTSGE
                     ILVNAIENIINERRD"
     gene            complement(59010..60401)
                     /locus_tag="KOU88_001156"
     CDS             complement(59010..60401)
                     /locus_tag="KOU88_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP-binding protein"
                     /protein_id="HBK3211059.1"
                     /translation="MNYYELLRIKKERHKNKNFLIIDGEKYTYENILSYSEELGKQIS
                     LGENIPILIYSKNIMFQLISFFAINYSKNIPIICHYNLSKKVLDDILLKNNISIIISD
                     ESMDVIDLYDDNNNEVAKKVNFSIFNPKFNIYMYQYKNLINYLDKSICMGALSSGSTS
                     VPKVLYRTYESWAGFFPIQNGIFNISGESILFVNGTLSFTGNLNSIMSVLYEGGSIVI
                     SSGLNCKSWIRIIKQYNVTNIYLIPTKLQLLVKHLKEPVLKVVSIFTGSQLLFEDTAR
                     NLKKYMPKSEIILYYGASELNYITYLCYDELIEKPLSVGRPFPGIDIYIREGKIFVNT
                     EYAVYNATKPYSVNDIGYYDNDGYLIFEGRSDDILNIGGFKVSSTKIENEVKKIPQIE
                     DAIVLPYSDTIRGNQIVLFVITIDKITKKDLLIKMKDNLMKNEIPKKIIFLNSFPYTS
                     SEKIDRLALLKML"
     gene            complement(60405..61541)
                     /locus_tag="KOU88_001157"
     CDS             complement(60405..61541)
                     /locus_tag="KOU88_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HBK3211060.1"
                     /translation="MEEVFILGGLRSHIGLKNGIFQFVQPELLGASVLKDLIKKYEID
                     KIDEIICGNAVGTGGNIARLMTLTAGVSNEVPAFTVDMQCASAMMSIDIAFSKVKSGQ
                     CDLIIAGGFESSSLQPMRTYHKNDKRYNTNNPNYTVAQFSPDDNSQNSMLEGAERVAE
                     LYQIEKADLDFWVKESHKRAKEAREEKILEDIISPINNSTYDEGIRDKMSQRLLDRMP
                     SILGKETITNAANSCLINDGASFIIICSKKYLEHVKKKPKAKIINTCTIGTDATLSPT
                     SAIQAMDKLLEIESLNYLDVSAVEFNEAFAVIDVLFQRKYPELIDRYNIFGGALAYGH
                     PYGASGAIIALHLLKALEKTKGRYGICSIAAAGGLGSALLLERV"
     gene            complement(61573..62118)
                     /locus_tag="KOU88_001158"
     CDS             complement(61573..62118)
                     /locus_tag="KOU88_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBK3211061.1"
                     /translation="MKNTKVNIQDLTKMSICVALLCISSYIYIPLPFTPAGVTAQTIM
                     INLIALILTPRQAFSTVGVYIMIGLIGIPVFGGGTSGIGKLLSPTGGFYFGFLFAALI
                     ISLLKGRNNDIKRYILITIFVGMPIIYFMGTVFMCYFNQMTVEAALFAAVVPFLIGDT
                     IKSVIASFLGTKLNNVLRRNL"
     gene            62442..63221
                     /locus_tag="KOU88_001159"
     CDS             62442..63221
                     /locus_tag="KOU88_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211062.1"
                     /translation="MKVNENNINNIDEELDELSRKVYLESPDFWISISDKIIDKVFDE
                     MLLFFAVKYNYFNIVCFAIENNYLDLNMPSKNKKYTNIMEHLLDTSKQNEDKKIYNYL
                     LSLNKGNNLDERPILDELNCNISSDTFEKKDIYLPKYLCPSCNSNIFDTGYKVSNDIT
                     YKFSSKEAEPIEMCSEVSSIRCCNCDELLEDITLDKLYNLCKIQNCNNCGSNLTKVGI
                     IAKKKMNFDENTEKFKDVSTFYCCGNCDSEISLSQREHFKI"
     gene            complement(63675..64103)
                     /locus_tag="KOU88_001160"
     CDS             complement(63675..64103)
                     /locus_tag="KOU88_001160"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBK3211063.1"
                     /translation="MIKKLNSKDINKIMEIWEKSTIKAHDFISKEYWQNNYNTVKNEY
                     IPISDTFVYDDGDEIKGFISIIDKRFIGALFIKPKYQNLGIGGKLLDYATKKYKSLSL
                     AVYKDNKKAVVFYNKKGFNIVKEQVNEDSGFKEYIMEYSK"
     repeat_region   64293..64715
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=64359..64387
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(64899..65165)
                     /gene="cas2"
                     /locus_tag="KOU88_001161"
     CDS             complement(64899..65165)
                     /gene="cas2"
                     /locus_tag="KOU88_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endonuclease Cas2"
                     /protein_id="HBK3211064.1"
                     /translation="MFVIVTYDIVEARSLNRIRRILRKYLTWTQNSVFEGNITEGKLH
                     KCISEIENIIDNSEDSIYVYEIKNPNSIKKKCYGIDKYSDEMFI"
     gene            complement(65168..66148)
                     /gene="cas1b"
                     /locus_tag="KOU88_001162"
     CDS             complement(65168..66148)
                     /gene="cas1b"
                     /locus_tag="KOU88_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated endonuclease Cas1"
                     /protein_id="HBK3211065.1"
                     /translation="MYKDYYIISNGDIKRKENTIYYYNLEGEKKILPVEQVDDIHIYG
                     EVDLNTKLINYISKYGVMLHFYNYYGYYSGTYYPRKKNVSGFSLVCQSACYLDKNERL
                     YLAKSFVESASYHILRNMRYYKVDESLIDTIKDELNDLNDVKEISELMGKEGRIRKTY
                     YKSFNQILKDDFEFYKREKRPPKDPVNALMSFGNSIMYTNVLSEIYKTQLDPTISFLH
                     EPSTKRFSLSLDIAEIFKPIIIDTIIFSLINNKRINKNDFEYQDKICYLSEKGKKKFL
                     QEFENKMQTTIKHRNLNRKVSYRMFIRLECYKLIKHFINDERYKVLKVWW"
     gene            complement(66151..66702)
                     /gene="cas4"
                     /locus_tag="KOU88_001163"
     CDS             complement(66151..66702)
                     /gene="cas4"
                     /locus_tag="KOU88_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas4"
                     /protein_id="HBK3211066.1"
                     /translation="MWLKFTKEGDFVPIDLEVLKVQGVKINYYYVCKRKLWLFSKGIT
                     MEQNSSRVLSGKIVHEDSYKRMKNKEILIDDILKLDIIKDEYVKEVKISSKMKEADEM
                     QLYYYLYYLKNSMGIEKKGTINYVKEKKQEELILTEEKERIIENTLININEINMQLSP
                     PKIEKKHYCTKCAYYEFCFVKEE"
     gene            complement(66717..69038)
                     /gene="cas3"
                     /locus_tag="KOU88_001164"
     CDS             complement(66717..69038)
                     /gene="cas3"
                     /locus_tag="KOU88_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase Cas3'"
                     /protein_id="HBK3211067.1"
                     /translation="MLYAKSNPVETLREHTDELLKQMNVLRESYGKNINSLDFLEEEI
                     FWQLLDFVIEFHDIGKAFSPFQELIKSRMDTKINEPKIVTHLENNVGHNYLSPAFIDY
                     SYIDRKKNKELRAVLNQVIVYHHERDIFIDKDFKNLIQKILDEDLINKVYELQHEFKV
                     RYPIKTEKLSKVYLQSVEKRIDKNHKYYNLYIMLKGMLHRLDHSASAHEIVECNSNMN
                     IGEYTEKHLVKEFGSLREVQSFAKSNRNKNIILIASTGMGKTETALIWIDKDKAFFTL
                     PLRVSINALFDRAKNIIGVGEANDTFLGLLHSTAIDYLEESNQENSNEIVDLAKLLSC
                     KLTFSTIDQIFKFPFLYRGYEKVYSTLAYSKVVIDEIQAYSPEIAAVLVKGIEMIHKI
                     GGRFMIMTATMPTIYIDELKKRGVMNSNLADLTCNTEKIRHCVSIVENSIDENLGKII
                     QNGMNKKVLVIVNTVKSAVEKYELIEEIVKPKGIDVNLNLLHSMYIQEDRAKLEKYIK
                     EFADSDSNGIWITTQLVEASLDIDFDELHTENSTLDSLFQRFGRCYRSREYEENSPNI
                     FIYTEKATGIGSIYDKDIVEKGLELLKTFINGKECVKMKEKYKVEMVKILYSKESLEG
                     TAFEKRFTSALNILDTITPYSLGSKDAQNILRNIEGYTVIPEDIYNKIEETLIKDYEE
                     LGQELINAYSNDDRQLINKIKSKRKKARREIIKKTVNLPIYKAKQNVIDIQVKGLEDL
                     KILLYKYDIYENKHTKQIFGKGVLISNEIDQFI"
     gene            complement(69049..69750)
                     /gene="cas5b"
                     /locus_tag="KOU88_001165"
     CDS             complement(69049..69750)
                     /gene="cas5b"
                     /locus_tag="KOU88_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas5"
                     /protein_id="HBK3211068.1"
                     /translation="MKVLKLDLFQETACYKKPFAMKITETYPLPPYSTINGLIHKILN
                     ATEYIPFNISVQGTYESIFNNYQTTYFYKKDSITSMPMNSHMLLNVNLIIHIGGDFDL
                     LEEIYDSLLNYDEHLSLGRKEDLVRINDIRFVEVNKFEVDEDIQLDDYENYKLSECNI
                     RMPIYIPKTSLQDTDIDGISYRLNNYYDNNAVEDKKRVWNKVDSYYVEDGNTISIGDI
                     LLDNEGDLLYFNNIN"
     gene            complement(69752..70666)
                     /gene="cas7i"
                     /locus_tag="KOU88_001166"
     CDS             complement(69752..70666)
                     /gene="cas7i"
                     /locus_tag="KOU88_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBK3211069.1"
                     /translation="MKRGLTFTVIAQAQSLNYGEGIGNISELKKLSRDDGNMYTFASR
                     QCLRYDIVRLAAELFNWNLQVVDKEKGTIQFKDNISIRESEEMDLFGYMKTNKKDEKD
                     KKGGSLTREATVRLSNAISLEPYRSDMDFLNNKGFADRIGEHPNLANIEQHLSYYTYT
                     VTIDLSKIGKDGEIELDNKEKCRRVVEFLEIIKVLNRNIRGRQENLSPLFVVGGVYEI
                     ANPFFLGRIKLKGDKNGFKINKQAIEEVIQGTFLGKDLKEFTYVGMVDGVFINKEEFK
                     GLFEDNFLSVDKFFGQLVKEVKEYYGVN"
     gene            complement(70668..72545)
                     /gene="cas8a1"
                     /locus_tag="KOU88_001167"
     CDS             complement(70668..72545)
                     /gene="cas8a1"
                     /locus_tag="KOU88_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein Cas8b1/Cst1"
                     /protein_id="HBK3211070.1"
                     /translation="MKLRVYRGDWFFNMGIVGFLNIIKKADKQAEIFIMEDYIEFDSL
                     FLENFHEYYFNYFMDEYDVSKRIKKNIDYSINFIKSKPDRIKDGIKKIKDSVKQQNDK
                     IKKFDEEKFNMIKEKLDSMSKIKSYDEFDSLEALVDETIDIFKIKSINDRLTANLYKY
                     VVQDNYFGQVSFFNVAKAKLDLDGLKQVMFNDYLRQIIYFGELEDLLEENDYDKLKNY
                     LNDRLNSIDKDINEKKVSKSSINTIEKIMKEINKNFIKKNKSIEDIKEYMDSLEVCEM
                     CGLYKGILDEYSESNFAPLGVSTNNARNMFWNQAYVPSICDICKLILFCTPAGATYTR
                     KNYLINEENEFYLFVNMDTCINELFERNNSLKVQKSESSDSKDENPFNQLIKSIVEEN
                     TLKSEWQLRNILFVEFKASIDSKKCKINYFNIPTYLAKFFTDKYANKKIQSIYDYKLK
                     SNVLDLLLKNRDLKHITNNILRNKVKNDMESNNKSNISGIDCFRVVQLRVLINSYKKG
                     VYKMDSKNLEKNDEKLKIIYYLGCDIHDYFVNKNSKNKIDGVSYKLLNSVKVGNKSDF
                     MDTIIRVFMSAEKQIPAFILDIEIEKDLDFESIGHAFISGLISGKYEGKDKLPNEKEE
                     K"
     gene            complement(72551..73288)
                     /gene="cas6"
                     /locus_tag="KOU88_001168"
     CDS             complement(72551..73288)
                     /gene="cas6"
                     /locus_tag="KOU88_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBK3211071.1"
                     /translation="MKMKIEFSTGCIPISYNSLFMSIIKEAIRKSNEDYYKNMYYYKE
                     KNNKKTKNFTFSVYIKKYSIEGDNFIIEDKVILNISTPDLELGFHIYNGLMTSKKCLY
                     KDYELTRIRIDLSREKKVTEERVLFNALSPICVKSKEGKFLEITDDRYIEELNYITNE
                     VVKNYRGNGLKRKLEFENIGLKKVVVKESLREFKKITGKEYQYINGYKGKFILKGDID
                     DLNLIYNLGIGFRRAQGFGDVDILEWR"
     gene            complement(73366..74283)
                     /locus_tag="KOU88_001169"
     CDS             complement(73366..74283)
                     /locus_tag="KOU88_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBK3211072.1"
                     /translation="MMILIQSRGKMKCKELSEELEVSERQIKSYKMYLEQAGIFINST
                     PGIYGGYEIDKCNSISLIKLLDSEVSILDMINSQLEYNNDIYKNEFNNIVEKIKAVLN
                     TGEKSDTYMDYFTVQAQRNCDYESEKNKCNEIIRAYTTKHKFWIEYYSLNSGNSERIV
                     HPYGLFNYKSDTYMVAFCEKRFKFIDFKLCRIKDYKVLEEKYNVDKSFSWDEYSKNSI
                     GIYKGEEINVVIKISHPFSTIIKEKVWVNNQQIIEYDDKSIMFKAKMRGYEEIKSWIL
                     SMGAYVEVVEPDRLRNDILLEIEKMKKIY"
     gene            complement(74563..76479)
                     /locus_tag="KOU88_001170"
     CDS             complement(74563..76479)
                     /locus_tag="KOU88_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211073.1"
                     /translation="MNIKQFAINNISRNIKAYLGYLASIVISSSLLFSFIMFTSHPDL
                     DVSQFPDYLKEGLKMSKIIAYLFLFFFVFYSVSVFLKSRYKEFGILYITGISKRQVMK
                     LIFIENMIINIVSSVIGIIIGLIFAKIFLVVMSTFLELSPLKFYIPFNAILSTLIYFM
                     ILAVLTSIFTSFIVKENQVLKLLKGTKTPKPEPKTSLMLAILSICLFIIAYYNAITST
                     DQYTTYLRLVPVTSLTIVATYLFFSQFSVFFMKKLKLNKRFYRKNTNMLWISNLIYKV
                     KDNARIFFLITITSAVAFTAIGTVYSFWKDVERQINLIYPNTIYYSTMTLHNDTKKPD
                     SKEKDKERMMFIENNLKKENVDYTRINGEFKTVFPKKSDFNVRIMKESKYLEITETIG
                     IKPISFEDNECISLLSSSLPGNKNVKENIIVGNRGLKVAKQVEECVMPAYYKNMYVVK
                     DNFYDSIESKFIVDRFTAFEVEDSSKTIEICREFENKFNNESGMQPYLFFSKELMIGT
                     GKLMYSTFIFLAIFIGLIFFVTTSSFLYNKFYMDCQVDKKKYEQLNKLGMTYNEIKKA
                     STIEIGIVFLFPYVVAVIHSIFALTALKNSFDIEVASSAVLVMGSLFLVQIVYFLIVR
                     NNYLKEIRLNLVNF"
     gene            complement(76479..77225)
                     /locus_tag="KOU88_001171"
     CDS             complement(76479..77225)
                     /locus_tag="KOU88_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001637630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211074.1"
                     /translation="MKILTVNNLSKVYGKKIIFNALNDINFSIEDGEFVGIMGPSGSG
                     KTTLLNMISTIDKPTTGTMELKGKNPLLLRGEELALFRRRELGFVFQDFNLLDTLTIG
                     ENIVLPLTLDKVSVKEQDERLNEVSTILGIKDLLGKRTFEVSGGQAQRTAIARALINN
                     PSILLADEPTGNLDSKSSKVVMELFQKINKENKVTTMMVTHDPLAASYCSRILFIKDG
                     SIYNEIYKGSSREQFYQEIMDVLTLLGGDN"
     gene            complement(77329..78180)
                     /locus_tag="KOU88_001172"
     CDS             complement(77329..78180)
                     /locus_tag="KOU88_001172"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBK3211075.1"
                     /translation="MSLDVIFILKSVIIAIVEGLTEFIPVSSTGHMILVGNLIDFKGQ
                     FAEMFEVVIQLGAILAVVVLYWKKIKDSVIEFFKFIFTGGKEGKIGFRFGMNVIIGCI
                     PFAIIGVLFYDNIKSLFNLQSVIIGFIVGGILLLVVETLFRKKNHSTDNIDKITPIQA
                     LKVGTLQVLSAWPGMSRSASTIMGGWIAGLNSPTAAEFSFFLAVPAMVASSGKDLFEF
                     DYSIMTPTLWIALVVGFIVAFIVSIIVMEKFVNFLKKKPMRVFAVYRIIMGVVLAVLA
                     FTNIISV"
     gene            complement(78428..79432)
                     /locus_tag="KOU88_001173"
     CDS             complement(78428..79432)
                     /locus_tag="KOU88_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3211076.1"
                     /translation="MKLFLKDYKGYIFIYYIGIVMTIIYCNLMKFISFGESLYILLFS
                     SFILLCFLIYKYYKNREVYNLFEKGVHSLEESFLYLGSSFLGRNISVILKQQHKLYQS
                     MIQEHKKIHSEHLTFINQWIHQMKTPISVISLQLQDYEGEEVTENIRKEIDRLNKGLD
                     MAMHFARADNFQKDFIVEKAKLNEIVSSIVNEEKRLFIKSGMIPKIQVDKFTYVYTDV
                     KWMKFIIGQLITNGVKYSKDYSNYLTIKSEENNKYVILSIIDEGIGIVSKDLKRVFDP
                     FFTGENGRKFGESTGMGLYLVKKVCDDLGHKVSIKSEVGKGTEVSIYFNKDVNSLIKV
                     "
     gene            complement(79442..80134)
                     /locus_tag="KOU88_001174"
     CDS             complement(79442..80134)
                     /locus_tag="KOU88_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3211077.1"
                     /translation="MSYKVYIVEDDISISTLLKDYIEKYGFEVIVEENFDDIMITFES
                     FKPHLVLLDVNLPKFDGFYWCRCIRQQSNLPIIFISARDGNVDQIRALESGADDYITK
                     PFYYDVVMAKIKSHIRRVYGEYSPKIDERIVELDGLKFYPERLELELNGENLIITKKE
                     GILIECLIKRYPKVVSRDYLLEKIWDDIEFVEENTLNVNVSRIRKRFEELGIDNAVQT
                     VRGLGYKLNKNW"
     gene            complement(80448..81407)
                     /locus_tag="KOU88_001175"
     CDS             complement(80448..81407)
                     /locus_tag="KOU88_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK3211078.1"
                     /translation="MKLKKLLIGITILTLATASLAGCAKKNNGEKLSEINLTYVKSPL
                     NVPSIIQKQDDLFGKEFKKDNIKVNFHEITTGPEQTQALAAGEIDFLHALGGTSALIA
                     ASNGVELKILNTYSRSPKGFMILTNNNSIKSAADLVGKKVAGPKGTILHQVLISALDK
                     EGLSMDDVEFVNMGIPEASAALSDGSVDAALIAGPAALKAMKSGSKLVANGEGLVDGI
                     IVTAVSTDFAEKHPEIVERFMKVEKETLEYVNNNFDEAMEKVAKEVDLSLEETKELYA
                     WYDFSLDITDKDISSLEDTQDFLIKNKLQEKKVNIKGLIYNAK"
     gene            complement(81440..82318)
                     /locus_tag="KOU88_001176"
     CDS             complement(81440..82318)
                     /locus_tag="KOU88_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211079.1"
                     /translation="MNNLVCDSGYIIRNLYKSYKVDNKEHVVLSDISLNIDRNHITVI
                     LGESGCGKTTLLRAIASLEGINSGEIRFINDNKEYRPNVGFVFQESRLMPWLNVSENI
                     AFHNQRKNTILNKVLRKFKHNKRIRSKIINDNFRSLETNDNLNKSNKYNRKSNIDVEK
                     YLKMMNLQKFKNSYPNELSGGMAQRVSIARALSFNPDMLLMDEPFSALDYFTRIDMQN
                     EVIRIHKSTNKGVIFVTHDIDEALKIGKKIVVFTDERKVKEFNIEDGYNRDLTSDYYI
                     KLKKDILMTMKSNKGI"
     gene            complement(82311..83093)
                     /locus_tag="KOU88_001177"
     CDS             complement(82311..83093)
                     /locus_tag="KOU88_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211080.1"
                     /translation="MVNKFNNKFLRLVKSVLIFFIILLLWKITNYLGIWSDYILPSPE
                     KVYSTFLNMISDGSIFINVYASMKRVLIGFAISTAIGVPLGIFFGIYSGVYEYFKSLI
                     NFLRNTPPLALIPMLILWFGIGEESKIIIIVLASFFPIFTSTLKGIKNCDSKLIEVGR
                     VFEFSKLQIIFKIIIPNAILDIAVGLKLALGYSFRAIIGAELVAASSGLGYLISDGKE
                     MSRTDVVIVGIIVIGLLGIITDYIFSIIVKKVSKGKMVEAYE"
     gene            complement(83094..83723)
                     /locus_tag="KOU88_001178"
     CDS             complement(83094..83723)
                     /locus_tag="KOU88_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211081.1"
                     /translation="MNKYLLINPVAERMYGEKFHLIKANLIKKGYIITECEPQLEYVK
                     KQYKEYTKKTENTMLDCRCPESISLLKRNNLINNFEVPMIEPILVRTCRVLYDKYIKS
                     KDDMLVVTCPCTQLRDFASEKFKDKGNAMFYTWKEFAEQEGVKSLGKIDESPIPLGYF
                     KDTFEKVLEVSSEDEILSEIQKIRNGFEDKYDIVEMFYCKDGCNNGDGL"
     gene            complement(84102..84728)
                     /locus_tag="KOU88_001179"
     CDS             complement(84102..84728)
                     /locus_tag="KOU88_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBK3211082.1"
                     /translation="MKYEWRKRDKELYLPKKNPVIVEIPEQKFIMLKGSGDPNSKEFT
                     EAIGVLYSLAYAIKTMPKKGIVPEGYFDYTVFPLEGIWDKGEKSKGLDVLIKEDLIYT
                     IMIRQPDFVTQDLLDKATDIVKKKKPHNLLEKVRFGSINEGLCVQMLHIGSYDNEPES
                     FDIMNEFCKKNKLIRKSYTHREIYISDARKVSPESLKTVLRFEVEREV"
     gene            complement(84804..85775)
                     /gene="nrdF"
                     /locus_tag="KOU88_001180"
     CDS             complement(84804..85775)
                     /gene="nrdF"
                     /locus_tag="KOU88_001180"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBK3211083.1"
                     /translation="MTFNLHKIHNAVNWNREEDGFTQAFWEQNVKQFWLPEEISVSKD
                     IKVWNELSNKEKELYKKVLGGLTLLDTKQGNNGIPSMMSLTENLQRKAVLSFMGTMEE
                     IHAKSYSSIFMTLLSNLEIDELFEWIETEPTLQRKADLVLAQYENTTNQEGLYLSMVT
                     SVFLESFLFYSGFFYPLYLSGQGKMVASGEIISLILRDESLHGKYIGLLAQEIYDSFD
                     KMDKEMLEEKMYSILYSLMENEIEYTNVIYRESGLEKEVVNFLKYNANRALENLGFEK
                     LYTVDAINPIVLNGLSTETKTHDFFSTKGNGYQKGVYEELEDEDFII"
     gene            complement(85788..87887)
                     /gene="nrdE"
                     /locus_tag="KOU88_001181"
     CDS             complement(85788..87887)
                     /gene="nrdE"
                     /locus_tag="KOU88_001181"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBK3211084.1"
                     /translation="MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFN
                     NLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMIDKHKFEFQSYMSANKFYQNYALK
                     SNDGKEILETYNDKVLIVALTLGNGDKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
                     EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGV
                     VGVAKMLEQSFSYFNQMGARQGSGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLG
                     AIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDKLVNDSDIRKKEINP
                     RQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGY
                     GGKNEWGQDISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSN
                     SKSHSIGLGAMNLHGYLVRENILYTSDDAIDFSNVFFAMVRYYSIKASMKIAIERNQT
                     FEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLLDEVKEK
                     GIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYY
                     QSAYRMDMRKVIDLVATVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYY
                     TRTKMTRDTHECLVCSV"
     gene            88365..89090
                     /locus_tag="KOU88_001182"
     CDS             88365..89090
                     /locus_tag="KOU88_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBK3211085.1"
                     /translation="MKTISKQELEKTLEKHYLWLKNNNAGEKADLKELRLENMDLRGY
                     CLSNIDFSWSDLINLNLEKADLENSIFNNSYLSDCSLKNSILKNADLSGASFRFCDLS
                     NSDIRGANLENSNLEHATLNGVISDESTRFFKLYCPETGAFIGYKKCFNFRMVQLLIP
                     SDAKRVSATSNACRCDKAKVLSITSIDGKESFKSARAYADENFIYRVGETIVAEDFNE
                     NRWKESTTGIHFFLTREEAIGYL"
     gene            complement(89218..90414)
                     /locus_tag="KOU88_001183"
     CDS             complement(89218..90414)
                     /locus_tag="KOU88_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211086.1"
                     /translation="MLKTNNLSVGYNNKVVISNINVEVKNGEILCLLGSNGAGKTTLL
                     RSLSKLISPIKGEIYLNGVNINCISRKALSKKMALVLTNRLLGDLMTVQDIVNIGRYP
                     YTGFFGSLSKKDLIMVDEALESVDALHLKKRYFDELSDGEKQKVLVARALVQEPEIII
                     LDEPTTHLDIKHRLELINILKKLSKEKSISVILSLHEIDIALKSCDKVALIKNNKVIA
                     YGQPEDVVDEDIINSLYELDDKNFNSLLGSVEISNKSKNEVFIIGGGGKATPIYRAFT
                     KKGIGLYSGIIHENDIDYEIGRTMGIKMFTENPFEPISDESFDLAIRNLNDSKIIIDT
                     GFSVGETNKRNIDIIKEALKLDKKVYSFRNRDESKKYYDSLDSKIEHIDKVSQIINSA
                     DINNLL"
     gene            complement(90417..91442)
                     /locus_tag="KOU88_001184"
     CDS             complement(90417..91442)
                     /locus_tag="KOU88_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBK3211087.1"
                     /translation="MDFINKMRIRNTTIFIVLIISMILTFLVCVAFGSVKIEFKEVID
                     VVLRGMDNTEHYKIIYNIRIPRVLATMVGGACLAVSGILLQIFFKNPIVEPYILGVSS
                     GSTLSVALMILGGYTLGFESVNSMSIFVAAFIGALIVMSIVILFANKVKNITTLLIIG
                     IMTGYVCSGITNVLQSFANSDKLKEFTMWSMGSFSGFTWEKVEILIIVGILGLLMTVF
                     IIKPLNAFLLGEEYAKSIGINIRFFRVLIVFISSILAAIVSAFAGPIGFIGLAVPQIS
                     KMIFKTSDNRVLIPVVIFLGSIVTALCDLISRVILSPVELPISTITSLLGAPIVVMLL
                     VKRKDRA"
     gene            complement(91514..92644)
                     /locus_tag="KOU88_001185"
     CDS             complement(91514..92644)
                     /locus_tag="KOU88_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3211088.1"
                     /translation="MKFKSNVLKQFFLIAMVIFMVGGLIGCSKSDKENKQASTGKKLE
                     LKYASGFSVEDLEDGIKKVTDGDNRELILIPKKIKIPEKYKNANIVRTPVDNVLIAST
                     TQACSLRTIDELDSIKAVTTEEQYWTIKEIKDLMKDGKIHYVGSNLAPDYEKIVDLNP
                     DLTIVSSGLSEADTKFIDKLKELGLNYVVDNEYKEQNPFGRMEWTSLIAAFYDKEDMA
                     TSELNKTVQKVEEVSKKIKNKAKPKVVWASVYEGSAYIAPKDSYVDNMIKMAGGINAC
                     ASIDSNEGRVSIEQLHEVAKDADIFVYSSSSDYAPNLDSIKSSAPVLADLDVVKNGNL
                     WVFAPDYYQSVDKTDELIVDLVEMFHPGTTGEKIKHYINYDK"
     regulatory      complement(92872..93053)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(93106..93999)
                     /locus_tag="KOU88_001186"
     CDS             complement(93106..93999)
                     /locus_tag="KOU88_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBK3211089.1"
                     /translation="MKAEFLTPVVTIFDEEGNLDKEGNKKVYDHLIDGGVDGLVIMGS
                     TGEFFNMSMDMQKELIDLVTSHVNKRVKVFIGTSRMCINESIELSNYAHNSGADGVMI
                     ISPYYFSLDDDSIELFYSEIAKNTEAEIYLYNYPDRTGYDLSPELTLRLARKHKNIVG
                     YKDTVTLMGHTRDLINTMKIEFPEFKVYSGYDENFIHNLMSGGAGCIGGLSNLIPEVC
                     SKWAEAYNNRDMEKVIEIQKYINKAMDFYLITNPFIPAMKKAMNIRGLQISDYMTAPF
                     VKPNEKQVCEIKKLMNELNIC"
     gene            complement(94079..94981)
                     /locus_tag="KOU88_001187"
     CDS             complement(94079..94981)
                     /locus_tag="KOU88_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBK3211090.1"
                     /translation="MKFVSFTEGENECKRTGVFSKDELFIIDVNSLNLSRNFKDLNEL
                     IQNVSSEDIIKLKTIINESTFYNYDVFKRERCTVHVPIEKPIHDILCVGVNYKDHLEE
                     TQTHFDDSFEEPQKTVYFTKRVTKAIGPEDEIDGHFEINNQLDYEVELGVVIGKTGVN
                     IRKEEVEDYIFGYTVINDISARKLQKEHVQWFRGKGLDTFTSLGPCILHKSAVPFPIK
                     LKVCSRVNGEERQSSNTGLFISDVSDIVSELSKGMTLEAGDIIATGTPSGVGMGFSPP
                     RYMSSGDVVECEIESIGILKNYIK"
     gene            complement(95031..96191)
                     /locus_tag="KOU88_001188"
     CDS             complement(95031..96191)
                     /locus_tag="KOU88_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBK3211091.1"
                     /translation="MKFYGYKRPDGRVGIRNHILILPTSVCASDTTRIIASQVQGAVT
                     FNNQNGCSQVHSDQQLTMDVMAGYAANPNVYGVIVVSLGCENCQNDLVVDAIKERTNK
                     PIKTLVIQEEHGTLKTIEKAVRYAREMAQEASLLRKEEFPISELILGTECGGSDPTSG
                     LAANPLIGELSDKLVDLGATSILSETTEFIGAEHILARRAVNEEVKEKILHIVHRYEN
                     SLKLVGEEVREGNPSPGNIAGGLTSLEEKSLGCIHKGGHRQISEVYDYAKQIDKKGLV
                     IMDTPGNDASSVAGMVAGGAQIVVFSTGRGTPSGNPIAPVIKITGNKITFANMEDNMD
                     FDASPVIYGPQTMEELTDDLLNMVVDVANGKQSKAESLGYTEMAIARVCNYV"
     gene            complement(96347..96652)
                     /locus_tag="KOU88_001189"
     CDS             complement(96347..96652)
                     /locus_tag="KOU88_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBK3211092.1"
                     /translation="MINAVIIDEKDNVAVAIEAIAKGSEISFKLKDKTVKTITALDDI
                     TIYHKLAIKDMAKGDKVTKYGEHIGEANQEIKSGQHVHIHNVRSVREDLDKQVMTNI"
     gene            complement(96750..97724)
                     /locus_tag="KOU88_001190"
     CDS             complement(96750..97724)
                     /locus_tag="KOU88_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate permease"
                     /protein_id="HBK3211093.1"
                     /translation="MIMDFIKKIPAGMMIVPMFIAAFINTFCPDIVQIGSFTTAVFSS
                     VGSATIIGVQLVCLGTQLQFREMPKVLKRGGILLGSKFAIGALIGILIGKLFGMDGVL
                     GLTTLAVISAVTNSNGSIYLSLMTSYGDETDCATMSLLTLNDGPFFTLIALGTSGLAN
                     VPLLSLLAAIVPILVGMIIGNFDKKMKEFLEPGCNLLVPFVGFALGSSINLASILKGG
                     LSGVLLGLISVFVGGIFIVFCDKFIGKRPGYAGWAVATTAGNAIAVPAAVALVDPSWQ
                     PYVATATTQVAAAVVVTAILVPLITSWWAKKYGCPKFPKQNEDGTITA"
     gene            98306..99082
                     /locus_tag="KOU88_001191"
     CDS             98306..99082
                     /locus_tag="KOU88_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBK3211094.1"
                     /translation="MTSDNHRPTARILDILEALAESENGYTLTEIADVINAPKSSIFP
                     IVHTLNARKYITIDKNTSKYSIGIRSYTLGSSFFEKRTIFNYIIDEMTNIVNSCSETC
                     QLGILDNNEVLYIGKVDSPEPIRLISYVGKKIPANCTGLGKALLCDFDKEKLISLYPD
                     GLKGFTEKSITDFDVLYDQLLEVQRTQIASECEESMEHLKCLAVPIRKNGCIRAAVSV
                     TLPLFRANDEKIELIKKLLLNAQKNIQSMMEERNEDIVIN"
     gene            99415..100560
                     /locus_tag="KOU88_001192"
     CDS             99415..100560
                     /locus_tag="KOU88_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBK3211095.1"
                     /translation="MSIYYVPPINLLGKGCLNEAKDSIKSLGTKKAFIVSDKFLVSNG
                     TVKKVTDILSQIDIDFVVYDEVKQNPTVTNVNKGLKILKSENCDFVITIGGGSPQDCG
                     KAISILATNGGDIRDYEGINKTSKKCLPIIAITTTAGTSAEVTINYVITDEDRHVKMI
                     MVDTNSLATMTVNDPELMISKPSNLTAATGMDALTHAIEAVVANGAYDVTDSTALYAI
                     KQIFKYLPRAVKNGNDIEAREQMCYACFLNGIAFSNAGLGNVHAMAHQLGGLYDLPHG
                     VCNAMLLPIVEEENAKSAPAKFRPIAEVIGMDVNNKSDKECVDFVIDKIKALSEEVGI
                     PKSLKDVGVDNPNFELLAENSMKDACAGANPVFFDKDKIIELFMKIS"
     gene            complement(100715..101584)
                     /locus_tag="KOU88_001193"
     CDS             complement(100715..101584)
                     /locus_tag="KOU88_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBK3211096.1"
                     /translation="MRGWICVKLTKLNIKKYRAPIYKYALANINLRSAKSTNSSIITV
                     IPQGAKMEVLDEEDDWIKVMYNSQEGYVYKELVSVSEYAWSNLNLREDKSTTSNIITV
                     IPEKSRVEVLQVDGDWSKVVYDDKIGYVFNYFLSIDGNKPNELDYKYFYTDMIKFVNE
                     NNIKSTSDYLIVTDLRNKYTYIFKKDNGGWGQLYKWQCTIGKPETPTITGIFYISGRK
                     PSFGTDEYSVKYATRIKGGYYYHSVLYDSTGSYIIDGRLGEALSHGCIRLSTENAKWI
                     YDNIPDTTTVIIH"
     gene            complement(101702..102415)
                     /locus_tag="KOU88_001194"
     CDS             complement(101702..102415)
                     /locus_tag="KOU88_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017208807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF434 domain-containing protein"
                     /protein_id="HBK3211097.1"
                     /translation="MNKISKRGFDDSDKRWFSSKELTRLIKAKEEIEWLLNRDYKIDP
                     VVTFVGDRYQFSIRQRDALKRAVCTDEKNIIRQSKRLSLDKIKEDTVNIDGFNLIISI
                     EVGLSGGTLVIGSDGNIRDLAGLRGTYKIIDKTEEALNLIGKFFNKYNAQNLKFYLDA
                     PVSNSGNLKYRILEHAKTWGIETEVELVKNADVVLEKLDRVVSSDAVIVDKCISYFNV
                     ARGIIEEYIKECNIINLNK"
     gene            complement(102786..104174)
                     /locus_tag="KOU88_001195"
     CDS             complement(102786..104174)
                     /locus_tag="KOU88_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK3211098.1"
                     /translation="MKKTFDAIIIGFGKGGKTLAGDLANRGLKVALIEKSNKMYGGTC
                     VNVACIPTKSLENSANSVKTKNINSWDEVQAEYEKAIDKKETLITKLREANYNKLNSN
                     ENVTIFTGMGTFIDEKTVQVKTENEIYELVADNIFINTGSRPFIPNIKGIENKNIVYD
                     SESLMNLRVLPKKMTIIGAGFIGLEFAGIYSSFGAEVTILNSNNGILPNEDVEDSEEI
                     IKLLAKRNVKIVNNANIKEIKEVSELAIVEYEVDGKSKELTSNMILVATGRKANTEGL
                     GLENAGIELNERGFIKVSETLKTNKEHIWAIGDINGGPQFTYISLDDYRIVINQLFGD
                     KTRTTNDRKNIPNSIFISPAFSRVGLNVKQAKEKGYEVLVAKMPVEAIPRAKQIGKAD
                     GFIKIVIDKKSNKILGASMICENSSEIIHLIQLAVDLEVEYTYLRDRVYAHPTMTEAL
                     NDILSPNMIKEV"
     gene            complement(104295..105572)
                     /locus_tag="KOU88_001196"
     CDS             complement(104295..105572)
                     /locus_tag="KOU88_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HBK3211099.1"
                     /translation="MQNVNLFLVFIEGIVSFFSPCILPILPIYLSILSNSSVENLKEG
                     KTSFIGSSLFKNTIFFALGISTTFFILGSSVKVLSMFFNENKDLIMFIGGIIIIIMGL
                     FYMGIIKSSILNREKRFNVKFKEMKAITAFILGFTFSFGWTPCIGPILASVLVMVSSS
                     SNHLSANLLIAVYTIGFILPFIITAMFYSKLFKTIDKIKSNMEIIKKIGGIILIVSGI
                     LMMVNGFGSISKHFNTSQNSKIESKQEENKRENSTDKEENSDGNDSQKDSNNDNNDKG
                     SNDEDRIKSIDFTLTDQYGKTHKLSDYEGKVVFLNFWATWCPPCKEEMPYIEQLYKDY
                     NKNNDDVVILGVASPNLGREGSREHVVNFLKDQGYTFPVVLDEDGALAYQYGINAFPT
                     TFIIDKEGYVTQYIPGAMDKATMASFIENQRNK"
     gene            complement(105709..106044)
                     /locus_tag="KOU88_001197"
     CDS             complement(105709..106044)
                     /locus_tag="KOU88_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211100.1"
                     /translation="MYNIDDMIYNCPVEALSNILGKKWVAIIIWKIQEDKKRFGELQR
                     AIPDCSKKMLVQQLDFLIEQGIIVNQKKLVNNVVESTYFLSESGLRLLPVMEKMIMWS
                     NKNLNCDKY"
BASE COUNT        35195 a        18354 c        11845 g        40731 t
ORIGIN      
        1 atttatgact ggctatttga taaatattaa aggggttatt tagttatcat tttttatttc
       61 taaaaatctt ttctcaaatg atttagttat ctatttatcc aattctttac ataatttaat
      121 gattaaaaat attaattttt tcactataaa gtataaatat tatctgatta ttaaaataaa
      181 tattaatact ataaataaaa acgaagcatg atttttattt aaataaatct caaacttcgt
      241 ctttacttac ttagatattt atttactttc taaatcctat tatttttaaa accttatctt
      301 tttaatactt caccacattt attctcagta atctctccat tttccaacgc aatttttcca
      361 tttacaatta catattcaac accattggct agtaattgtg gctttgaaaa atcaatatct
      421 tctgacctag aataactata gttatccatg tcaataactg ctatatcagc tatcaaccct
      481 tctttaagaa tacctctatt ttttatttta aattgcctag ctggtaatga agtaactctt
      541 cttacaatct cttccaatct aacaccagac tttctgtaca tattgaagaa aattggaaaa
      601 gctcctcttc tttgtagttc aaaccatgac atatccccac ccacactaaa caaacaatct
      661 gaaccaacca taacaaatgg attatcaatt attttatcat catgtagttt atctgggaaa
      721 tcagctctat acattcctcc taaacaaaag ataagttctt cgtctccatc taaaagtaaa
      781 tcgagtaata acttgtcttc atctattcct ttttgtgtag ctatttcacg tattgatttc
      841 ttttccatat taatatcttt agtgtttaga agtattatac tccccctatc tccaagtata
      901 aatgcttctt ttaatataag tgttcttccc tcttcatttc taagagcatc cattacccca
      961 tttataccta attcaaatag actagatgat attgccataa taaattgaat tactcttttt
     1021 ttcttcatac aatgcccaga acttcttggt actgtgtcaa ccattatttc aacaccatta
     1081 tacctagcct ttaatatctc atcaaatgct tctatttcaa ctggacttaa gtgagatact
     1141 tgaaccctag caccactttt ttgcccaacc tctatggctt cttttactgc attatatctt
     1201 cctatgtaat ctctaatatg agatgtatat ataccatcat gctctttaat ctgccttgca
     1261 atatcaacaa gttcatcaat atcagcatac ttacttggta tatatgccaa tccagtagat
     1321 attccaaaag caccactttt cattccatca tttattatat ctgtaatttc atttttttcc
     1381 ttttctgtag gaggtctatc cttagaacct cccataacac tccatcttat agtcccatgc
     1441 cccaacaaga atcccatatt gacagaaata ccacttttag atataaggtc acaatattct
     1501 gtaaaattat tccaacattt atttttatct ataagatact ttttttcttc ttcaagtaat
     1561 agaccatttt tatacatata ttcatataca ttttcagaag aatatggtgt tatagaatgt
     1621 ccacaattac catttatagt tgttgtaact ccttgtttta gaaacttttc aaatttacca
     1681 tctagtattg ctactatttc ttcatgaaca tgagggtcaa taaatccagg tgttataact
     1741 tttccacaac aatcaatctc tttatttgta ttgctattta tcttagaatc tatttttgct
     1801 attaagttgt ctttaattgc tatatctcca taaaaaccag gattacctgt accacctatt
     1861 ataaatccat tttttaagat taaatcatat atcaaaatat tccctcctta aaaaccaatt
     1921 tttaaataat cttaatgtaa tttttatatt tgaaaatcaa attattatat ttcatatttg
     1981 aaaattcact attatttcat tgtaattagt cactaagctt atctttatac atagctcttg
     2041 caattaatat agtaccaaat acacatataa gaactactag agactgtggt attatacctt
     2101 gctttgataa tataatagtc aatacagata ttacaattgc tactaggcct aattttttat
     2161 cttgtaaaaa tacttgtcca aaaactgacc caaatagagc tggtaaaatt aagtttaatt
     2221 tttctactac ttcagctgga attttagata gtacgcttcc tcctaaaatt acccctatag
     2281 ttagtatact tatattcact aaaatagata cagctattcc tattgtagat attatcgagc
     2341 cttcttctgt acctgattca acttctgctg ccttttgagc tgctattgaa catggtagcc
     2401 tcatattaga tatattacca gaaagaaaac tcatataagt tcctgggata cctaagattg
     2461 gtgaataaga aactggttct attatgtaat ttggagcact catactgaca attgccattg
     2521 tacttgctaa taatgctgat attggaggca taataccaaa tccaaagctc aaaattattc
     2581 caggaactaa tgctgctata atccccaaag atagtgttag tcttccatac cttatcataa
     2641 aaggtaaata ttcttcattg tatatagatt ttactttact cataaaactc cccccttata
     2701 ttactgaagc tattatcatt ccgctaaaca ttgatattgt aagcccccac tctcttaacc
     2761 attttatatt tttcttcttt tcaagcatac acaatattac cattatagcc attccactta
     2821 tacatgcaat tgttccatta tcaaaacgca acaccctatc agcatttaga tatgcaaatg
     2881 aacccaacat tgctcctaga gatattattg gtataaatga tttcttgcca ctagatataa
     2941 cattggttat cttatctagt ttatgtccaa atagtaatgt gaatattatc catcctaaag
     3001 aacctaatat catagtccaa actgcatttg taaatgcaag ttttgtcatt tcaggagaac
     3061 ctaaagttat acctaatgca tctgttccaa atccggctga cattgattca aaaattacag
     3121 aacctataaa tgataatctc atccatgcta taggcccacc catagttact ataagcgata
     3181 ccattccagc aaatatagtc attgaaggcc caatagctga aatagcacta ctcttaacag
     3241 ctgactttat ttgtttatct gttattccca ttgttttacc aactttgcaa gattttatag
     3301 caaatataag ggattgtacc actactattg atactgctac tgtactcgct atccacaaaa
     3361 gtggatgatt agctaatttt aaataatcca tttataaaac ctccctataa atcctcaaat
     3421 tttattaata tttctaatat atctatttcc aaacctgttt tagtactcta agtatatttc
     3481 cacctagtac cttctctatt tcctcatcac tatatccatg ctttactaaa tatctaacaa
     3541 tgttttttga agtttctgtt gggttctcaa gaccttttac atattctact ttgggatgtt
     3601 cttttgttcc tgttattttt tttatatcaa atttagcagc tagtactgag tgtaatttta
     3661 catggtcgcc atatactgta tctggtccaa aagctacatg gtctattcct actaaatttt
     3721 taatatactc aaaatgttcc ataaatgact ctattgaatg ttctttattc ttctctgtta
     3781 ttgtagtatg aggtgctgct tctacaccta taacccctcc ttttttagca catgctatta
     3841 atacttcatc tggagttagt ctctttgtgt tccataaact tcttgcccca acatggctta
     3901 atattattgg gtccttgcta tattctatta catcaagtgt agtttgaact ccaacgtgag
     3961 agcaatctat tgccattcca attttattca ttctttcaac agcttttttc ccaaaatttg
     4021 taagacctcc atctttctct tcttttagtc ctgaacctaa tgcattggat tcgctgtatg
     4081 ttatacccat taaccttata ccaaatccat acagtatatc tattctatca agttcatttt
     4141 ctattggtgc tgcaccttct aatgttggta tcaatgctac tttaccttca cttttagctc
     4201 tgtatatatc ttctactttt tcacacttta tgacaaaatc ttgatgagct aaatcacata
     4261 atctcatgcc taaatctatt aatatatcat cccatttcca ccctgaattt gatgttatcg
     4321 tacatacacc atccattaaa ttatcaaata tagcatcata atatcctctt gataatgctt
     4381 cataagcaca tctttgttta ccttccctat tatattcaaa tatatctctt tctaggtgtt
     4441 ctggaaataa tactggatgt tcatgtaatg atataaatat tttttcatcc actatacttt
     4501 taaccttagc ttcttgaata tcatctaatt caataaggta ttctttaact cttttatctc
     4561 ctttacacat ctcaatagat gaaatatctt ttcctttttc taaataacta taggcttcat
     4621 atcctttgta agctgacttc ataacaacat cctccaagtt ctacaatttt ttatattttt
     4681 cctatgtagc aattgatgtg ccaaaatata aattttaatt gtataataaa tcttgcaaaa
     4741 aataaaaaca gtagtaaggt tgatatttac tactgtttta ttaaaaataa tcttcttaga
     4801 ttatttattc aatatttttg aattatctta atcttaaaga taattttatt tatttctatc
     4861 cattataggg atttttttag ggtgttttgc ctttttagtc ccctatatca ctcccttaat
     4921 ttttacatat gatataaagt tctttccttc atcagttata aaactacctt gtttttttac
     4981 tccagataaa agtaaaccat ggctctttaa cttatctatt ctttttctaa tttggtctac
     5041 acttaaaact atatcttttt cttttaaaat ctcttgcagt ttatttcttc ctaataatat
     5101 atttttatta ttccaagttt ctatactggt caatatacat atactttcct caaagaaatt
     5161 agattgtttg aaatctaaga taattgaatc gaaattttca ttaactaaag tattgttttt
     5221 ttcaaatcta aattgttctg gcaaatgctc gtaatctact ctatcttcct caactatagt
     5281 atcaatataa taaattaaat ttttaagctc tcttacattt cctggccatt catacaatgt
     5341 taaagcttgc attgattcct ctgtaaaaca tttgttgcta tttatttcat ctaaaaaata
     5401 cttacttata agaggtatat cttccttacg ttctctaagt ctaggtatct ctatatgtaa
     5461 tacattaatc ctataataca aatcttctct aaaagaacct tctttaattt ttttctttaa
     5521 atctttattt gttgcagcta taattctaac atctattggt ataattttac ttccgcccat
     5581 tctcataact tctttttcct gtaatactct tagcaatctc tgctgtacat ctaaagatat
     5641 atcacctatc tcatctaaaa aaattgttcc tgtatgtgct ctttcaaata tacccatttt
     5701 tccacctttt attgctcctg taaaacttcc ttcatcatag ccaaaaagtt cactttcaat
     5761 aagtgtatct gacaaagaag atagattaac tgcaacaaat ggcttgtttt ttcttagaga
     5821 ttcattatgt attgcctggg caaatatttc ttttcctgtt ccattttctc caagtatcaa
     5881 cacagaaaag tctgtagttg ctatttttct tgcaatatta attttttctt ttattatttt
     5941 actctcacct acaacactct caaatgtata ctttgataca aaaccttttg actgaagttt
     6001 attttgaatc ttgtcctcaa gcacttgaat tgcacttata tttttaatgc ttataatact
     6061 ctttattcgt tcattatttt cataaacatt tactttatta attatcagtt ttttgttatt
     6121 taaatttact acttcatcat taacttcatc ttcttgaaaa aatatttttt tgacaacctt
     6181 atcactaaat aagtccataa agttattaga tataatttca ttttggtcta ttccaactag
     6241 attagaaaat actttgttgc aatatataaa ttttcctaat ttatcaacag aagcaatacc
     6301 ttcatctata atctccaaaa aactcttcat ggttttattc atagttgtat aatacctata
     6361 tccacttact gtatcttcat tgtatttttc cttaataata tgtagtttat ctatagatat
     6421 atttagtttt gtaaagattt ctataactgt atttatatca attaccttat cacctatgtc
     6481 aattatttgc tttatgtttt gtggtatgct gtttctgctt cccgtaataa ttccaatctc
     6541 acatttagac ttatcacaac ctggataata tggtattaga ttaatatgaa ttaatcctag
     6601 ttttctaatt atcttggcag tttcatctgc tgactcttta taagcatcta taaccataac
     6661 atcagaatca ttttctatac ttattatctg atttatattt tcaatattta tagtacgatg
     6721 tactattaca ataggtatat ttttatcaat attattatgt atatattcct ttatatcatt
     6781 gtctgaacat actacaagct catagcttga cagttcaata tttatcctat ttacatatac
     6841 caagttatct atattacaaa attctccaaa tatattttcc aattgttttg atatatctat
     6901 atttattttg tcatcagttg atacaaataa aatattatgt tttttcatag tcccacctcc
     6961 tgtttaacga gtatagaaag taataatttg gtctattgta gcacttttta aaaaagtttt
     7021 aaatcttaaa aatcaaattt tgtaccattt actattattt tccataataa aataatgtaa
     7081 gctatctttt ttcacatata atttaatttc taaaacggtt agtttgacat tattggaata
     7141 taaacaaaaa tttaatataa attcgttaat atattaatac atttttaaga atgacaagga
     7201 ataaattata acaaatttta ggaatatata ataatagggt ctcagaactt agttacaagt
     7261 tctaaaaccc tatttgttta gtgtaaaaaa catcataaaa tttagcttaa atcttttcac
     7321 ataatattac tctttttcta agtgataata aaatatatct attcctctaa aaactgtaaa
     7381 aattcctgat taaatagttt aagctcatca tagaatatag catgaccact atactcaaaa
     7441 gtatataaaa ttgaatcttc tattttttca ttcataaaaa ctgcaaattc atacggacat
     7501 atttcatcta atttcccatg aaatatacca gtaggcactc ttacacattt taaatcatta
     7561 aataattctt catctcttaa agatacagca gttccaatag tgccaatacc tgatgcacta
     7621 aaaccaatat cattaaacca tcttctaaag ctttctggtg gatttgatgc aaatactttt
     7681 tcgccaaaat cggttaccat ttctggtcta tcagtacatg cttgtgctat caatttattt
     7741 acatcttcac gtgtcatacc atatggaaat tctggaggtc tttgtacaaa tgatggtgca
     7801 gcagctgcag ctaataccaa ttttgacact ccatatccat taaataaact catataccta
     7861 agtacgattg ctcctcccat tgaaaaacca acaagggtaa agtcttttaa tccaatagca
     7921 tgtaccacct tataaatatc gtctgctaat tggctataag tatatcctcc tgatgttgca
     7981 tcagatttac caaaacctct taaatcaatt gaaactgttc tatatccgag ttttggcaat
     8041 atatttgttt gatattcaaa tatcttatgt cctaagggcc aaccatgtat aaaaagtaca
     8101 gtttttttag cactcggatt caaatcatat actgctatgt ttatatcatt cacatataca
     8161 taatacatat caacagcaac tcccttcaag aaaatgtatg atggttattt tatatatatg
     8221 aataaaatga tgaataacta aattttcaaa tttatttaca atacttctct attgcctttt
     8281 caaataaact tacatgaagt ttttcatcta ggattattct atttaatata gcttttatat
     8341 aagggtcttc aataagactt atatctttat aataattatt aatagccaca tgctccaaat
     8401 gcaaatctag ttttaatctg ttacaaatag aatttccata acatacaaaa ccaccattcc
     8461 aatatgcacc acaagaactt gtagaacctc tatatacagg atttccaccc aataatctta
     8521 tagtctttgc taatatctcc atatgtaaca tttctgttat agatatattt atccacattt
     8581 cacttaactc tctatgcgtt tcatctaaat caaaattatg gtatagatat tgatttacac
     8641 tcgtaaattc acttgatact ccggcatagt catccatcaa taattctgca tagtacttat
     8701 ttggacctaa aacttttatc tctggatatg gctcatcact tgaatatcca tttcgcttgt
     8761 gcatgtcata atgtgcatca ctcataatat ctcctccttt aaatttaatg tatgatatta
     8821 attgtatgca tcacaacttt ttcatataac ttagataata aaatctactt aaataataaa
     8881 aagccatatt aattaaaatt aacatgacct tttatccaca aaattacttt ttaattattc
     8941 atcttttcca gctactgata gctctttaat aacaactgaa ggtgaaccta tactactcat
     9001 tggaaattct aaatcttccc ctatagcttc aatatctttc aacaggtcaa aatagtttcc
     9061 tgctactgta atttgctcta ctggaaatac tttttttcct tctttgatat aaaagccttt
     9121 ggcagctaaa gaaaagtctc ctgttactga atttgcacct gaatgaagtc ctgcaaagct
     9181 agtaaccatc aatccttcat ctatatcctt tataatttca tctaaagatt tatctccttt
     9241 ctctatataa aaattagttg gatatatgct tataggtgat gaatatgaag attttattcc
     9301 atttcctgta gtctttacac ctgccttatt agctgttttt aagttatgaa gtaaagttat
     9361 aagctttcca tttaaaacaa cttctttttt aaatgtagct actccttcat catcaaaagg
     9421 agtagatgcc ataccatttt ctaaaagtgg gtcatcaact attgtaacta taggagatgc
     9481 tatcatgtct ccttctctat ttttcaataa agataatcct ttttgagctg aatctgcatt
     9541 aaatatccca gaaaatgtgc taagcaaaga taccatagct tcattaagca atatagtttt
     9601 atatttacct gatggaatac tcttaccacc tactttagat aaagcattat caacaccaag
     9661 ttttgctatc tcacaaggtt ttatttcttc aatagaattt gctatattat atcctattcc
     9721 atcatatttt tgtccattgt cttctatgat aggaactaca aaccctataa acatattagt
     9781 tttattgctt aaattaagac ctttagtatt agatatacca ttacttgata cagaataaga
     9841 tatagtacat ttagataaat ttaccacctt atctgaataa gctttagtct ctctttccat
     9901 ttctaaagct aaatcaatca acttatctgc ctctaaattt tctagctctt tagaataagt
     9961 ctttacatca ttatagtgct tatctccttc atatataaat tgtacatctt cattttcaat
    10021 agtgtttact ccatctttta cattttttat caacatatca acagctttat catctaaaat
    10081 ttctgtataa gaataaccta tctttccatt taccttacct ctaaaagata aaccaaaaga
    10141 tttatcaaga ttgtatttct caacttctcc ttcatatata tttatactta aattttctcc
    10201 tgtataataa tatatttcac actcttcaaa accttcactt agagcctttt taaataatat
    10261 atctttaaaa tttttaagtt ccacaattat ccctcctatc ttccacctac agtaatttct
    10321 tttaccctta tcataggttg gcctacatta gttggtatac ttcctgatga tgagccacac
    10381 atcccctgag cttgttttac gttattccca accatatcta tattcataag tatatcgcta
    10441 ccttttccaa ttaaactagc acctctaact ggctcttgta tttctccatt ttttattaag
    10501 taaccttctg aaactgcaaa attaaactct cctgttacag gatttacaga accaccaccc
    10561 atttttttag cataaagtcc atctggtatt gactttataa tatcttctgg tttatcctct
    10621 ccagcagcaa tataagtgtt agtcatcctt gaagttggtg caaatttgta gttctgtcta
    10681 cgagaacttc ctgtaggatt cattcccatt cgtctaccat taagtttatc tatcatataa
    10741 gacttcaaaa ttccattttc aatcagtata ttcttttgag ttggatttcc ttcatcatct
    10801 atattcatag aaccccagta gtttggtatt gtaccatcat ctatagctgt aatctttgtg
    10861 gaagcaatct gttgacctaa tttatctgca aatacagagt tcccctttgc aactgatgta
    10921 gcttccaaag aatgtccaca agcttcatga aatattactc caccaaatcc attatctatt
    10981 gctaccatca tattacctgc aggacaattt ttagcatgca acatagtatg cgctactcta
    11041 gctgattctt ttgcataata ttctgggtct atttcttcaa atatttcaaa ccctttacaa
    11101 cctccaggac cttcaaatcc agtttgattt tcattgccct tagatgcaat tgaacttatc
    11161 cccagtctgg ttcttattct tctatcctca acatatatac cttcagtgtt tgcaattaat
    11221 attttttggt ctttatccaa atagctaaca cttacttgag atatatcatt actaaattct
    11281 tttgcactct tatatgcaac cttcataaca cttactttat ctctatttcc tattgaattt
    11341 ggataaattt ttatattatg tatgttattt attttaatac tgtcatttaa tattacactt
    11401 tttccatctt ccaattttcc taaagcaaca gcagctttgt atgctacatc caacagacta
    11461 tttaatgaat tgtcacttgt ataagcatat atacttttca atcctttaaa tattcttatt
    11521 cctatgccat aatttcttcc acctattgca ttttctactt tattatctat taaactaata
    11581 gaattattta tagtgtcttc ttcaaaaatc tcagcaaaat ctcctccagt aattagacac
    11641 ttttctaata ccttagaagc tatatttttt gaaagcataa atttacctcc tactttaaat
    11701 ttttaattaa cttttattca atctttttac ttgttaacaa acattatata ctatattact
    11761 taaaataagg taattatgaa tatattatac atatgtttta tactaaaatg ttatcacatt
    11821 ttatctatac atacccatat aactagataa ttaaaatgta taatattatt tgctatagaa
    11881 aataatacac tcatacataa taaattttag gagtgaagta tatgaatcaa gaatatgtaa
    11941 aaggaaatcc tatttttact aatattaata aagttccaag acaatttcca taccttactg
    12001 atgatattga tactgatgtt ataattgttg gtggtggcgt aactggatgt atctgtgctt
    12061 actatctagc taaaaacaat ataaagtctg tcattcttga aaaaggaagg attgcacatg
    12121 gaagcactag cgtgacaact tctctattac agtatgaatt agatgacaat ttgatagatt
    12181 taacagaggt tatgactcta aaagatgctc taaaagcata taacctttgt acttcagcac
    12241 ttgaagaatt agatacattt atagagctat atggaaataa gtgtgattat gccaaaagag
    12301 atactctact ttatactgcc aacaaacttg aagttaaggc tatcaaagaa gaatataact
    12361 taagaaaaga aaatggattt gatgttgaat atattgatga atccacaaac ccttttagct
    12421 ttgatttaaa atcaggattg atagcaaaga atggaggacg agaattagac ccatataaat
    12481 atagtcacca tttgattgat gtaagtttaa aaaatggtct tcaagtatat gaaaatacag
    12541 aagtaaaaaa agtagattta tcaaatgata aggttactgc tgaagtatcg tatggataca
    12601 aagttcatgg taaaaaatta attgtagcta cagggtacaa tacaagttta tttacaaaaa
    12661 gaaattttgc aactaagtca aatactttta atatagcaac gaaaccactt aaaaacatag
    12721 cttcttggaa aaacaacatt ttaattagag ataactgtga cccatataat tatctaagaa
    12781 ctactaaaga caatcgatta attataggtg gtgaagatgt aagttttgat gatatagaaa
    12841 atgaaacttt agccaatgaa aagtacgata ttttagaaca aagattgaaa agtatgttta
    12901 aggatataaa agacattgaa gttgaatata aatattgtgg ttgttttgct tcaactttag
    12961 ataatttagg ttttattggt ccagataata aaaataacaa tctatggtat tgcttaggtt
    13021 atggagcaaa tggtatactc tttgcaatat taggaggtat aatgttaagt gaattatatc
    13081 ttggcaaaca aaataaaaat atgaaattat ttaaagtaga tagatttgat aaatagatat
    13141 tatatattaa aagactgtaa aaagatgaaa ctttataatt ctaaaagtta actttgatac
    13201 agtcttttat aatgttcctt ttaaaaatac tttatttata attaaatata aagtaaaatg
    13261 ttaaaatata actgataaaa tttagtcata agataatatt taagtttatt tgatgaaata
    13321 tggaggaatt attatgaagg aaatactcgt tattgctccc actaaaggaa cctatgaaaa
    13381 atcaattcac atagttaaaa aaaacaaata tacaaatatt gatgttgtat ttggcaatct
    13441 aaaagaaggt atacctcttg ctgaaaaaag tattaatcat ggtactagaa ttatcataag
    13501 ccgaggtgga acttacaata tgttaaaagc tacttacaat atacctatag ttgaaattaa
    13561 agtagatgct tatgatatta taaaaagtta caaagaggta aaaaattcca acgaaccatt
    13621 tggaataatt ggatttaata atgtcatcta cggtttcgat attatagaag aaatattgaa
    13681 taagaaaata actatgattg aaattgaaaa agaagaagaa atttatgatg ctatagaaaa
    13741 gtacagaaag aaaggtataa acacatatat aggagatacc actgttgcac atattgttaa
    13801 gagacttaat tgtaagggaa tattaatcga atctagagaa gaaaacatac ttagagccat
    13861 tcaacaagca gaacaaatac tcgaagcaac caaggatgaa caaaaaagaa gattacagat
    13921 agaagctatg acagattttg tacatgatgg aataataaca gttgataaaa attttaaaat
    13981 aacattattt aataagagtg ctgaaaaaat atttggtata aaaaaagaaa atgcacttta
    14041 tcataatgtt gtagatgtta tcccaaacac agttcttcca caagtagttg agactatgga
    14101 acctcaaatt ggtgaaatac aaaatatagg gagtacaaaa attattacaa atagagttcc
    14161 aatcattgtt gatggtcaga ttcaaggagc tgtttcaaca tttcaagata gcaaggagat
    14221 aagttctttt gaacatacaa taagaaggag cttattaagc aaaggtctat ctgctaaata
    14281 cacttttaat gatataattc atgctagtga aaagacaaaa gattgtatag aacttgcaaa
    14341 aaaatatgct tgttatgata ctcctatgat tattactgga gaatctggag ttggtaaaga
    14401 actattttgt caaagtatac ataactatag taagcgtaaa aatgcacctt ttgttgctgt
    14461 aaattgtgct gccatacctc catctctaat agagagtgag ttttttggtt atgaggaagg
    14521 ttcatttaca ggtgctagaa aaaaaggtaa agcaggtgta ttcgaactag cacatgaagg
    14581 cacaatcttc ctagatgaaa taagtgaaat ccctcttgaa cttcaaggtc gattattgag
    14641 ggtattgcag gaaaaacaag ttatgagaat tggtggtgat aaagttattc ctatagatgt
    14701 aaaaattatc tgtgcttcaa ataaagactt aaaaaatatg atgcgcaatg gtttatttag
    14761 acaagacctt tattttagaa taaatatact aacattatat cttccttcat taaaagaaag
    14821 aaaagaagat attataaaat tatcagaatt ttttatacat aaatattcaa gcaaatacaa
    14881 taaaacgcct ttaattatca ctccaaatat taaaaaggca cttcttgaac gagaatatga
    14941 aggtaatata agggaattgg aaggtatgat ggaaagggct gttattgtgg aatcatttga
    15001 ctcgatttta ttagaaaagc ttagcaatga atatacaaat aatatagttg ataaagataa
    15061 tagtgatttt gaatgcagta atttagattt aaaaacttta gaaaaaaaat atatctataa
    15121 aatttataac gaaaataata gaaatactac aaaaacctgt gaaattctaa agataactcg
    15181 ctccactcta tggcgtaagt taaaagaaat agaagatgat gtttaaaaat aatacatatc
    15241 tatatatatc aaaacgtttt atgtttaatt ttaatacata agacgtttat ttgttttcaa
    15301 taaaaaatac aattatatga taaaaagaat ctttgtaagt gaaattctcg tcaatcatac
    15361 ttttaattat aagtaatcta cagcatttca atcgattatt aaaaataatc ataataacta
    15421 aagatacaaa ctctatatat tggcatagta attgctttta taatacctat ataaaaatga
    15481 aagggagtga tactagatgc acatcttaaa atcagtgaaa aagataccag gaggacttat
    15541 ggtctgtccc ttgttatttg gagcactatt taatacagta tgtccacaag ctcttgaaat
    15601 tggaggattc acaacatcct tatttaaaac tggtgcaatg agtatacttg ctctattttg
    15661 tctatgcaat ggagctcaaa tcaatatcag acaagctggt aaaccattga ctaaaggtat
    15721 agtacttaca gcaacaaaat ttataattgg tgcagtatta ggtattattg ttagtaaatt
    15781 tattggacct aaaggtataa ttggtattac acctcttgcc atagttgcta ccatgactaa
    15841 ttcaaatgga ggtctatttg ctgctcttgc aggtgaatat ggagactcca cagatgttgg
    15901 agcaatatct atcttatctc taaatgatgg tccttttttt acaatgcttg cttttggagt
    15961 aactggactt gcaaatgtac ctatagtagc actatttgca gcacttatac caatactact
    16021 tggatttata cttggtaacc ttgatgaaga tatacgagaa tttcttgcac ctggtacaac
    16081 attattaatt cctttcttcg cttttccttt aggagcagca ttaaacttta atcaaattat
    16141 aactgctgga ctacctggag ttgtacttgg tttaggagtt actataataa caggtatggg
    16201 tgggtacttt gtaatgaaac ttatacgtgc agaacatcca gcagtaggtg cagctacagg
    16261 tacaacagcc ggaaatgcag ctggtactcc tgaagcttta gcagctatag accctactct
    16321 agctacaata gcagctgttt caacagtaca ggttgctgct gctattattg ttacagcaat
    16381 atgttgtcca atgttagttt cctatctaga taaaagagaa aaaaagaaaa aatctatttt
    16441 taaaacaaat aaaaatattg aagtaaatta atacttaagg aggtaaaatt aatgaatgca
    16501 attattcatg caaatgaaaa agataatcta gttacatgtg tcagaccttt agttaaaggt
    16561 gaaaaagttt caattgatgg aaagtcttac atagtaaatg ataatatacc tgtctttcat
    16621 aagatggcta cagaagatgt aaaaaaaggt gatgttgtat acaaatacgg tgaaattata
    16681 ggaattgcaa cagttgacat aaaaactggt gactatgttc atgtacataa cattgaaagt
    16741 acacgtggtc gtggagataa aaaataggag gaagttaaaa tgaaattaat gggttattta
    16801 agagaaaatg gtcagtttgg tattcgtaat catgttttaa ttattccaac atctgtatgt
    16861 tcaagtgaga cagctacaag aatagcatca cttgtgcctg gagcaatagc aatccctcat
    16921 caacatggat gttgtcaaat tggttctgat atagagctta cagcaaagac attaatagga
    16981 tttggaaaaa atcctaatgt tgccgcagtt ttagtagttg gtcttggatg tgatggtatt
    17041 caagcaaaag aattagcatc tgaaatagct acaacaggaa aaaaggtaga ttacattgtt
    17101 atacaagaat gtggcggaac attaaaaaca gtttctaagg gagctgaaat agtaagtaaa
    17161 atggctcgtg aagtatcaaa agaagtaaga gttgaatttg gtatgagtga aattacatta
    17221 gcacttgaat gtggtggttc tgacccaaca agtggaatag cttcaaaccc ttcaataggc
    17281 gttgcatcaa accttcttgt agatgaaggt ggaagtagca tactaagtga aactacagaa
    17341 gtaattggtg cagaacattt gttggctacc cgttttgaag atgaagaaat gaaagataag
    17401 tttcttaaat ttgtaagtga tgtagaaaaa agagcaattg ctatgggaga agatttacgt
    17461 agtggtcaac ctactccagg caataaaact ggtggacttt caacaattga agaaaagtca
    17521 cttgggtgta tgtataaggc aggcaataag ccattcaaag gtgctcttga atatgctgat
    17581 attgtacctc ctgataaaaa aggattatat tttatggata ctccaggtca agatatagat
    17641 tctatcactg gtatggtagc aggtggtgca caaattgtaa tcttttcaac tggtagaggt
    17701 actccaacag gaagccctat ttcaccagtt attaaaatca ctgggaatag tgatacatac
    17761 aacaaaatgc cagacaatat cgatataaat gcaggtagaa ttataacaga tggtgctaaa
    17821 atagcagata taggtcaaga aatatttaat gaaataatag aagtctgtaa tggtaaacat
    17881 accaaagctg aaagtcttgg tcatagagaa tttggcattt acagaatttc atctacattt
    17941 tagattgtaa caaaatatct tttataaata taatacttat gtagatacat aagctaaaag
    18001 ttctttctaa tactataaaa attttctata ctgaaaagga actgtatcaa aattattttg
    18061 aaaacagttc tttttttaac ctcttttact caaaatatta taaaataaga tttaaacaat
    18121 aaacgtatct tgattaatct ctaagaagac ataaataaag ctaaatgtaa agtgggataa
    18181 ataaaattta atatctttgt atgaaaagat atttggtata atatgtctga gagaattctt
    18241 atttgtaaac aaataaagga tggaggatga aacaaaagaa tgaactttga aaacacaaaa
    18301 aataaaaaaa taatagctac tttactattg acacttcttt taatcgtgtc attaacatgt
    18361 gtcactttta ttatgaatct aaataaagta acacataatg aaacagaacg atatcttgta
    18421 gaagtttcac aaggtatttc cactacaatt aatgtgaaat gtaaaagtat atttaggaca
    18481 ctatattcta tgggagatac ttattttgag attaatgata gtgaaaaaga agtcaataga
    18541 tacttatcaa aaaaattaaa attatttgaa tttgattggt taggtattat agattctaat
    18601 ggaaattttg taagtgccct taaagataca ggtaatgtta aaggacaaga cttttataga
    18661 aaagcccttc aaggcaaaga aacaattact cctgttaaat cacaatctgg tacatatgga
    18721 attttatatt ctgtaccact atacaatggc gataaaattg ttggagctgt tgctgcttgg
    18781 aatactattg atactatgag aaatttatta agtgtagaaa gctttcatgg tgaaggattt
    18841 tcccaaatta tcgaccaaga tggaaatttt attgtaagtt cagcaaacaa aaatgctcca
    18901 aaaaatgtgg taaatttttt tgacatgatt aaacaccaag gaaaacaggt tgataaaaat
    18961 aaacttgaag aaatgaaaat aaacttaaaa aagaacaaaa ctggttctat gtattataca
    19021 ttaaatgatg gtatttctaa ggcaatgcat tatcttccat tacaagaaga aaacttatac
    19081 ctcctttcaa ttgttccaac aaaaacagca agtgcacagt ttgatttact tctaaaaaaa
    19141 gcaatcttca tcaatatttt aattgttata ctatttttat tgcttattat attgattatg
    19201 tttataaatc aaaagaacag ggcacaactt ataaaaatcg cctatgtaga ctctgtaact
    19261 aaaggttaca gtaaagcacg ttttgatatt gaagctaaaa aaattataca gtcatcttca
    19321 tcagaaagct attcattggt atctataaat attcagaaat tcaaacttat taatgattct
    19381 tttggtagtg aagcaggaga taaaacatta aagtacatac atgatgtcat tagtaattat
    19441 ctagaaccag gagaattgct ttgtcgagtt tctaatgacc agtttaatgt acttattaaa
    19501 actattcctc aaaaagaaat tcttaagtac atagaaaata tcaccaatga tattaatagt
    19561 ttcaataaaa atgaagaatg taaatatttt atagctctat ctataggtgt atataaaatt
    19621 gatgacccaa atctaccttt agtttcaatt caagaccgtg caaatgttgc acgaaaaaat
    19681 aataaaggaa acattggaaa tcatccactt tatacatgtg ttttttatag tgatttagag
    19741 cgtttaaaaa tgattaaaga aaaagaaatg gaaaatagaa tggaggaagc attaaataat
    19801 aacgaattta tagtatatct tcagcctaaa ataagcctca aagataatac tattgtaggt
    19861 gcagaagcat tagtaagatg gcaagaccca aataaaggtc ttataccacc agacgagttt
    19921 attcctttct ttgaaaaaaa tggttttatt acaaaactcg accactatgt ttttgaaaaa
    19981 gtatgcagta tgataagaaa atggatagat aatggagaaa ctccaatacc tgtttcagtt
    20041 aatttttcac gtgctaattt aaataatata gattttttag aaaaatacag aatgcttcgt
    20101 aataaataca acattcctgc taagctctta gaaattgaat taactgaaac acttgtattt
    20161 gaaaatctcc aaaaattaat taatataata gaccaaatcc atgaagaagg ttttcaatgt
    20221 tcactagatg actttggaag tggatactct tcactcaata tgttaaaaga aataaaagtt
    20281 gacacattaa aacttgaccg tgcttttttt agctcaccta atgcagataa tattgctgaa
    20341 aatcatgtaa tagaatctat agttaatttg gcaaaaaaat taaatatgaa tagtatatca
    20401 gaaggtgttg aaacaatctt gcaaatggat tatcttaaaa aaattaattg tgatatgata
    20461 caaggatatg ttttttcaaa acctctgcct caagaaatat ttgagaaaat gacttttgga
    20521 aaaaaactag aagaaaccag tatggatagt tccgtttaaa taaaataaaa aacttgtctc
    20581 tataaaataa ttttaatcat tttataaaga caagtttttt tattttccaa tttaatttta
    20641 ttttctaaat ttcttatact cggcttgttt taaattccct ttttaagaat aataatacga
    20701 ttatcatagc aataaaatct gcaactggct gtgccaacca aacaccatct aaattaaatt
    20761 gaattggaag tacaatgatt aatggtataa ataaaataaa ttgtcttaaa agagttaaaa
    20821 acattgaatg tttaacttta cttatacact gaaaatacac aggtcctaca atagaaatcc
    20881 ccattatagg caatgtaatt agatttaggc ttatacctct tactgctata tccatcaaat
    20941 ctgaatcttt attaaatata cctacaaata cttctgggaa aacttgtact actaaaaatc
    21001 caaatgacaa tatgacaact gacactatga tagataatat taaagttttc tttgcacgct
    21061 catattgttt tgcaccataa ttgtatgata ttatagtttg cataccttga ttcaatccaa
    21121 acacaggcat cataaacatc aataaaatag atgtaagtgc tgtcatagct ccaatagcta
    21181 aatctccacc ataaaccttt agagaattat ttgtaaacat gtgagttata cttatagcta
    21241 cttccatagc aaaaggtgtc attcctattg caaatacctt ctttactata tctttattca
    21301 attttaagtt acattttttt agttttaaat tggatttccc tcttataaaa taatgtatta
    21361 cccaaaagaa tactactatt tgacagagta ctgttgctat agctgctcct tttataccta
    21421 aattaaatac aaatataaat atagggtcca atatcaggtt taatacacat cctacaatca
    21481 ttgtccttgc tgctaatttt ggattacctt ctgccctaat tgcattatta agagaaaatg
    21541 caactaaatt aaatatactt ccaaccaata tgacactcat atagtctttt gcataaaata
    21601 ttgaatcttt acttgcaccc aaaataaaaa gtatatcttc taagaaaact aatcctaata
    21661 tagttataat taaagagata attatagata atgtcaaagc attacctaat atcttctctg
    21721 cttcttctct atttctttca cctaacttta tagacaatct tgtgctagca cctactgata
    21781 ccaacattcc aaaagctatt attagagtaa atactggcat agttacacca agacctgcaa
    21841 tagctataga gccaatacct tccatagaac caataaaagc tctatctact acattataaa
    21901 gtgaagttac catcattgct attattgcag gtatcgaata cctaaataat aaaatccata
    21961 ttttttcatg tcttaatgct tcttgattct ccatgttgtc accatttaca ccatgtcata
    22021 agttatacaa attggtttat ttgttcttgg gtctgttgct atttctgcat caatattaaa
    22081 taattctttt agattatcct tcgtcataac atcatatgca tcaccttcac aaactatttt
    22141 acctttctta atacctatca tgtggtcagc aaatcttgct gcattattaa gttcatgtat
    22201 taccatgaca atagttcttc cttgtttttt atttagttca tctaataatt ttagtatctc
    22261 caattgatgt gccaaatcta aatatgttgt aggctcatcc agtaataata tatcagtttc
    22321 ttgtgccaaa gccatagcta tccatgccct ttgtctttgt cctcctgata aatcttccat
    22381 atttctatcc ttaaactctg caattccagt aacttctaaa ctccaattta caatctctct
    22441 gtcttcttta ctagaattac caaatccact tttatgagga aatcttccat aagaaattaa
    22501 ttctgaaacg gtaagaccac taggagcttg agggctttgt ggaagtacag ccatatcttt
    22561 tgctatttct ttagacttct ttttgtagat gtcctctcca tttatatata ttttcccact
    22621 attagggcta ataattctac ctatagtttt aagtattgtc gattttccac aaccattagc
    22681 ccctatgatg gtagttattt ttccttttgg tatatttaaa tttaaatttt ttataatatc
    22741 tgtgtttcca tatgatacat ttagattctt agtatttata cagttcataa caacaccctt
    22801 tcctaatcat ttaccaacat taaataaata aagtacggca ctcctattat agaaactact
    22861 atacctactg gtatttctat aggtgctaga agatttcttg atatagtatc tgctattaaa
    22921 agtaataatg ttcctatcaa tgctgatact ggtattaatc ttttatgctt tggtcctatt
    22981 atttttctac ctatatgtgg agctattaaa cctaaaaatg aaatactacc tgctactgct
    23041 gtcgatacac cagataaaat tactgcatat attataagtc ttcttctttg tttttctaca
    23101 tctacaccaa gacttataga tacttcatca cccaaattta aaacatctat atatttagat
    23161 ttataaatag ttatacccat aaaaatcact ataaatggaa gcacagctat tacatatttc
    23221 caactggttc cccaaatgct tcctgatgtc catgccataa ccctattaaa ttcttgtgtt
    23281 gtaaatttca attggaatat cgtcaaaatt gaagtaaaag ctatgtttac acctatacca
    23341 ataagtagta atcttgacga atttatacca cctttccatg caagagaata tataagaaat
    23401 gctccaaata aagctcctat aagtgcaaca ataggcattg taaatacagt caagttactc
    23461 ataccttcat atacattacc attcataagg tatatataaa ctactacaaa caatgcagca
    23521 cctgaattta ttcccaaaat tccagaatca gctaaatcat tctttgtaac tccttgaagt
    23581 attacacctg ctgttgataa tgcagaacca accaaaagtg ctattactat tcttggtaat
    23641 cttaatttaa atattgcaat ttcatgatta cgctcaccct gccctaaaaa agtctttata
    23701 acatccattg gttctataga aaatgagccc atatttaaac tcaataaaaa agtgataaaa
    23761 ataagcacca ttaaaattga tataacaagt aatgttttag aatttatttt tataatattt
    23821 ttcatagtac ctatttctcc ccctttctaa caaggtatat aaatattggc actcctataa
    23881 gtgctgttat agaacctact ggtgtctcat atggaggatt tatcatccta cttaatatat
    23941 ctgtatatac aagcaataca gctcctaata ctaaagagct cggtattata tacttataat
    24001 ctgaacctac tattccttta gctatttgag gaactataag acctataaaa ataatattac
    24061 cagacactga cacagatgct ccagtcatta atattacaag tactatacat ataaatctaa
    24121 caaagttagt tttttgtcct aatcctattg ccacttcttc tccaagactt aatatagtta
    24181 ttcttggagc cataataata gctaaaataa atccaatacc accagctaca aatagcaatt
    24241 ttataccttc ccacttcact cctacaagcc ctcctgatat ccagaaactt aattgttgag
    24301 ataggttaaa atacatagat attgctgatg ccaaagaaat tagcaatgta ccaagagcga
    24361 ctcctgcaag agctaacttt acattattaa ctcttcctct tgatttagaa cttataaaat
    24421 atataaataa tccacttata cttgctccaa taaatgcaaa catcattaca ctaaaacttc
    24481 catgtataag ttgaggaagt tttttttgaa gtaccagtga tatcgaaatt gcgaatgtag
    24541 ctccttgtgt aattcctata acagatggtt cagctatagg atttctcgtt attccttgca
    24601 ttattgcccc agaaactgct aaaaatcctc caacaagtgc agctgctatt gcccttggaa
    24661 gtctaacatc ctttactatt ctcatattta ttccatcttc catttttatc aaactatcta
    24721 taacagttga tagattcata tcttttgccc caatagttat ggataataca attccaaata
    24781 caagtacaac tatacttact aatatcaaca aataagttat atttttttta ctcagcttag
    24841 tcaattatcc tacctccttt tcccttttaa tcgtcagtat aatatcatct attaagtatt
    24901 ttaattttaa gatttattaa aaataggtgt gaaaaatgaa tatcattatc tcacacctac
    24961 taagttaaga attactttgt taattcattt ttaactgatt ctaataatag ctcttttcca
    25021 attggattgt atgattgact gaaaaatgga gcagcatcaa gtattgttac attaccatct
    25081 tttactgctc ttatttgagc ccagatagca ctattttcta aatctttttt atctgcttct
    25141 gtagcaatta caactatatg gtctgcatct atatctgtta aaccttccat acttaccatt
    25201 ggtagtgtta ttccatcctg ttttggcata ttcttaggtc tagctaattt catatcatca
    25261 ttgattagag tacctattcc accatcacta aataccataa attgacctga acttgccaac
    25321 actggtaaat aagttttttc tccattcttt tctataactt ccttacctaa ctttgtagct
    25381 ttttcatcat acttctgtag ccaactttta gcttcttctt ctttgtcaaa taactttgaa
    25441 acatcagtta acttgcttct ccagtcattt gcataatctt tcatcataac tacaggagct
    25501 atttctttta attggtcata tattttttct tgtctttgac tcattattat taaatcagga
    25561 tttacttcta atatagcttc catatccata gtatccatca ttgagtgccc aactatcttt
    25621 acacctttaa gctcttctct tatgtaactt ggtaatttat cagtttcata tgagtctaca
    25681 tttgctgttg caacaggctt ataacctgct aataatagtt cttcactact tcctgatata
    25741 tcaactattt ttttaggatt tgatggtatc ttaacctctc ctttaacaga ttgtacaact
    25801 cttgtctctg atttatcttt atcctctgta ttcttatctg aacatgctgt aacaagtact
    25861 aacgtagtta taatagatat aaatattgca agtgatttta tttttttcat gattacttct
    25921 cctacttgtt tattatactt acatgatatt gattatcata agcacatatt tattatagca
    25981 tttttctatt tttagtcaat attattttgt aaaaggataa aaattcctaa ttaatcttaa
    26041 ttatatatag cttagataag gttttcttat attaaacagt atttttttta agaattggac
    26101 acaaatacaa tgacttttca gttaaacaat gataaaatgc aatttataga taatgaattt
    26161 agtaaggagg attcaaaaca tggtacattt agtatattgt gataatgcag gaaaaaaagg
    26221 agaaaaggtc ttagataaaa tcttggctgg aacaaaaaca atggttatta gaggtgctgc
    26281 tggtagaaaa ataccacata gtagagtatt tgaagatgag ttactttatt ttatggaaaa
    26341 aggaactgca aaaatatctg caaaagccac tgttaaaaag gtagaaaact atgttaaatt
    26401 aacagaagat gaaatttcta aaattttaaa tgaaaatcaa ccaaaattaa atttatctga
    26461 aaagcaaaaa gttcgttggc ataaaaaatg tttatgctta gttgaatttg aaaatgttga
    26521 agaaataaca cctcttgatt ttgaccatca aggaaatatg gatgattggc ttattgttga
    26581 aaaaattgaa gatgtagttg ttggtactag tataccttac aattatgaga agtctaaatt
    26641 ttaaagtatc aataacataa tactatattg ctaaactcta cttaaataaa aaaagagtgc
    26701 atttaataat tataaaaatt atttttatac actctttttt aataataaat ttaaattact
    26761 tactttctaa tctttcatat acatctataa attcttctgc taattgttga aaattcatag
    26821 ctgtcattaa atggtcttgt gcatgaataa gtataacact tatttcagtt ttattaccat
    26881 tagcttcatt ttgtatcaat tctgtttgga atttatgagc tttatgaatt gattctttcg
    26941 acttttcaat acattctcta gctttatcta tattcccgct ctttgcttct tttattgctt
    27001 caaatgctag ccctttcgca tcacctgcaa atccaattat tccaaaagat atctctatca
    27061 tcttctcatc catttattcg acctcctaaa tatctctata gcttgatatg actaatccat
    27121 tcttttctaa aaattctttg acttttttag atgtaagtat cttgtgctct ttcgttctat
    27181 caatagcata agatgtagaa tttaaaatat aatcatctaa aaaagctggg tgagacataa
    27241 tatccactac atcatacttc attatttcgt ctatattttt tataaaatat tcttcactta
    27301 cattttcctt ataaaaacta tctattaaag gaactacttt agaatactct aaattatatt
    27361 caaatccacc tcttattgga agattatact tggttacaat cttctctatt actgacttta
    27421 aacttactaa agtatggata tgatggtgac tatctaaatg agatatatct attccaagcc
    27481 cttttaccct atctatttga gcacaaagtt ctctataaat ctcatcacaa tccatttttt
    27541 caataatttc gtctgtaatc ctcctaataa aaaaaccgtc tttatcaaca atagttttta
    27601 agttagataa taatggtcta ccacaactta aagtcatatg aactccacaa tttaaagttt
    27661 tattttcttt aagtaagcct actccatgtt ctaccccagg catatttgcc atcatagaag
    27721 tagacctaac tataccatta ttatgagctg aaattattcc atagttcaca gcttcacaat
    27781 atccaaaatc atctgcattt attataattt tagtcatacc ataacctact ttctatagac
    27841 aactatctat taaatctagg aagataatct ttatgagctt ccaacatttc gtctaatata
    27901 gtttttgcta agtcatcaga tggaatcaat gggtttatac aaagtgccaa aagagcagat
    27961 tcataatcgc catatacagc tgctttagct gccaatactt caaatgattt gatttgactt
    28021 actaatccat gcacagaatc tggtaaatat cctatactta ttggttttgg gccatttttt
    28081 gttattacac tacttacttc taccgcttgt tcatctttaa aatctcttat agaaccctta
    28141 tttaatgtat taactacttg gatatctttt ttgtcgttgt atatagaact tattaaatta
    28201 caagcagcat cactatagta agcccctcct cttttttcaa gttgaggtgg ttttacatct
    28261 aatttttcat ccttatataa ttcaaataat tgttcttcca attctttaac tacttgacct
    28321 ctagcttttc cctctttaaa ctctctcaac tcatcctcaa gcatttcttt agttttatag
    28381 tagtatctat ggtatggaca aggtattgca cccaaagatt ttacaaattc agcattaaaa
    28441 tcaattgcct ttatattttg catacttata tctgctttga caaatttatc aattgcttct
    28501 tttgtaacat cttctccatc taaagataca tttagaccat aaaccatatg attaagacct
    28561 gcaaaatcca tacttattct gtcactttct acattaaata gtttggcaac atcatttttt
    28621 aaatgaattg gcacgttgca tagacctata tatcttctaa aattagtata tttgaataca
    28681 gcctctgtta ttattcctgt tggatttgta aaattcacca tccatgcatt tggacataat
    28741 tcttccacat cttttattat atcaaatata actggtattg tgcgaagggc tttaaataaa
    28801 cctccagcac cattagtttc ctgccccata actccatgag ataaaggaat agtttcatct
    28861 tttattctcg catctaaaag acctactcta agttgtgttg tcacaaagtc tgcatctctt
    28921 agagcttctc ttctatctaa agtaagattt attttcatat ctactccagc tttttttacc
    28981 atcctcttag ctagatttcc aactatctct aatttttctt ttccagcttc tatatctaca
    29041 agccataatt cctttacagg taactcttca tatctattta taaaaccctc tacaagctca
    29101 ggagtataac ttgaacctcc tccaattgta actattttta gtcccttttt catctcatta
    29161 taccatcctt acctataatt taatatactc tacaaaaccc tatacattta tttaccgaaa
    29221 taaaactacc tagttgttaa ttttcaattt attagcttcc attttttcag acgctatgac
    29281 aaatggaata tatattaata ttgataatat taaattaaat agtgctaaag ctccgccagt
    29341 ccagtcacct gtagccattg ctccacctaa tataggaggt gttacccaag gtattttagg
    29401 taaaattact ggtgctacta atccaaaatc tattgctaag tatgatacag cactacatat
    29461 tactggtgca agtacaaatg gaatcataaa tataggattt aaaactattg gaagtccaaa
    29521 tatcaatggt tctcctatgt taaatattgc aggtggacca cctaatacta tcatctcttt
    29581 acgtcttctt ccagctatta ataaagctac tattaatccc aataccattc cagaaccacc
    29641 taaatataca aatgcatcaa agaatgcacc tgcaagtaca tggtatcctt ccgttgctcc
    29701 tgcttgagcc aaggcagcat tttctccacc taatttcata agtatagttt ctgtaaaagg
    29761 aagtgctata tttgcaccat gaagtccaac agtccaaagt atatgaatta taaatgcaat
    29821 aagcattgta gaacctagac tatcagctac atttgatagc ggtgctccta aataagtatt
    29881 taaaatatct gttaagaaac ttccattaga aagcattttt ataaatattc ctattacagt
    29941 aaatatcatt atagttaaca ttcctggtat taactttgca aatgatcttg aaactgctgg
    30001 tggaactcca tctggcattt ttatagttaa tttctttacc ttagataatc ttacaaatat
    30061 ctcagttgat aataatccta ttaatataga agagaataaa gctgctgtac ctaagtaggt
    30121 ttgttgtatc attccccatc cttcaactac tgtagttcct ccctcaggaa ctattttacc
    30181 aatttgtgga gccattataa aaaagataga taaagctata agcccagatt gtaacccatc
    30241 actctcataa gattttgcta gaaaataagc aacacctatt actaaaaata ctgccattgt
    30301 acctattgct ccccaccaaa ggtcgcctcc aaatgtggtc cagttttctc caaatatact
    30361 tgccatcaaa tttttgtatg cttccaatgg taagttattt atcaatgttc ccaatgcacc
    30421 taccatagtt ataggtatca ttactataaa tgcatctctt actgctacta agtgcctttg
    30481 agctcctatt ttagcagcta caggcactat atatttatcc ataaatgaca tgaatttttc
    30541 cattttacat cctccagtac aactttattt tgaactattt aactctacag ctctatctaa
    30601 cacagctttt ccattacatc ttccataatc catcatattt ataacttcta ctggaatatt
    30661 atatggtttt gccatttcag ttgcttttcc taatacatat ctaacttgag gccctaaaag
    30721 taagacatca caattttcta tttcattttt taagttcact tctgatatag cccatatttt
    30781 tgcttctata ccgttttcct ttgctgcatc ctccattttt gtaactaata aactagttga
    30841 cattcctgct gaacaagcta acattatttt tatcattttt tcccctccaa attagattca
    30901 ttaaatgttt tttaagtcat aagtttttta aactatacat ttaaaatatg cttttctatt
    30961 aattttttct taatgtatat atcttatttt taaatgtata tacatttaat tcttgatatt
    31021 attatatacc aaatgtatat acatttcaag aaaacttttt cattttattt aaattttatt
    31081 cgacaacagc attcaaagtt aatgtatatc catagtgata tgtgtgtgag tactcaaaaa
    31141 tctcactatt ttgtaactta caaatttggc ttatatataa aagtggctct ggttcttcta
    31201 attttagatt atccatacac tcttcattcg atattacagc ttgtacttct ctctctgaca
    31261 tggctatctt gtatccacac acttcttcaa caaaattata aagagaattt tcacaatgag
    31321 tcttatttaa atttggaaat aacttaactg gcatataagt aatcatatat gaaactcttg
    31381 catcattggc taatcttact ctttttattt cccaaacatt ttcttctaaa cttatattca
    31441 acttacttga taaattttca tctgcctgaa ctatttcaag agataccaat atattagata
    31501 ctttatagcc tttactttcc atctctttag taaatccact tacagacgat atattatcat
    31561 atatattatt tgcaataact atactaccta cacctctttg tctagttata tagccttctt
    31621 taactagatt attaagtgca gaccttacag tcattctagt tacattaaat tcttcactca
    31681 gctgtttttc agaagggatt aaatcccctt ctttcaaact gtctgaattt attaactctc
    31741 taacatgatt ttctataact ttataaattg gctctttcat ttaattcact ccttattaaa
    31801 tcttttatat aataagataa ttttatatac aaacaaagaa aatgtctata catttaagat
    31861 aatttaaatt ttattcagaa atcttgtaca actttccgag ttttaataaa gatataaata
    31921 gacttatcat taatatacct tttaatatac ttgataaggt tatactccac catacaccat
    31981 ttagacccaa catttctggt ctagatataa agtaagccaa tggtactctt gcaccagtca
    32041 gtatagtaat tataatagaa ggtatatagg ttctccctaa tcctttgaaa gctcctgttg
    32101 ttattatttc taaacacata aaaaattgag aatagcctaa tattttaaga taaattgctc
    32161 ctttttctat tgcctcactt tcatctataa aaatagaaaa tatactctct cctgcaaata
    32221 ctaatactaa agtagttatt ataccaagta cagaagatac agttatagct attttgcaac
    32281 ctttatttat tctagaatac ttcttggcac cataattttg tccaacaaaa ctgcctaatg
    32341 caactgatag cccttcagcc gtcatccagg aaattgcttc tatttgtgag cctacttttt
    32401 gtactgcaac agccacaggc ccccatgatg ctactattac tcctaatagc attgagaata
    32461 ctgtaaacat accactttgt attgctatag gtaatcccaa tttatacaga actttataat
    32521 atttagtctc tatttcttta aatagtctta atttaaaata ttcttcttta cttttaacta
    32581 ttatatatat aaaacatgta gtaactacta tctgagcaaa tacagttgca atagcagctc
    32641 ctgcaacacc aagttttgga gcaaatcccc atccaaaaat taatataggg tcaagtataa
    32701 tattagttat taatcctact gtattaatac gaaaaggagt tttactattt ccaagaccat
    32761 tgaaaattgc agtaaatact ggattaataa aataaaatac catacctaga gctactatta
    32821 tcaaatactg tctagacatg gttataactt ctaagtctcc taatctaaaa aaacctatca
    32881 attgtttatt aagtactatt aaagaaattg tatatattat tgctagtata atatttattt
    32941 ctattgctga cttcatatat gatttagtag tgcttatatt atttgcacca atactttgtg
    33001 ctacttttat ctctccacct acttttgaaa tcataataaa tgccattgca agccatggaa
    33061 aaaaaccagc tgttccaact gcagctactg ctttacttcc ggctttacca acccatatca
    33121 tatctatcat gttatacccc atctgtataa atgaagtccc cattattgga agtgatagct
    33181 taagtaattt ttctgtaatt cttccttctg ttaaattaag tctgtctttc attttccacc
    33241 tcttttatat taaatttatt tgcttatata gctagattaa tcattttatt tgattgagtt
    33301 cactatcctt caatttatat tatcatatct caggattgca tctcaatcat acttatgttt
    33361 aagatacagt attttaccta tctatgataa aattaatact tatgaattta aatctagcca
    33421 tttcatcaat acatattcta acccttaact taacttcaat taagtataca tatcgtaacc
    33481 aattagaata ttttatacgg tatcttccat taataaacaa ccaatatcaa tgatttatat
    33541 ataattttat ttatacataa aatagtatac tataataata aaaaaactat atttgaatgc
    33601 tttaagcatg tttactaatt gtaatttcca cacaaatttg ataatatatg aatatattat
    33661 ggtgaaattt atagatatat attaattatg gggagattgt gggaggttct tttcacaaga
    33721 catttaagct atgaaaataa ataaaaaatt caatagagtt gatatgcagg tttcaatact
    33781 cactgcaatt attgtaataa tatcttcctc atgtgtatat ttttttaatt atacactaac
    33841 ttataagagc atgatatact ctttaagtga gaggtcaaaa catatctatg aatatgtaga
    33901 aagaaatatt gataaaaata cctttactga aattaattct aaagaagacc aatcaaaaaa
    33961 gtcttataaa agttctaaaa tccttttaga atctgtaaaa aatactactg gagtcatgta
    34021 tctatatact gctaaaaaaa caaaagatgg atcactagta tatgttgttg atggtttaaa
    34081 ttcatctagg agtgatttta gaagtgctgg tgatttgata gaaaaagaga tttggggaga
    34141 ccttaacaaa gcattagata atcatatatt gttacctaaa aagattaaat caacatcttg
    34201 gggatacata tttatatcgt attttcctat tcacaatgat gttggtaagg ttgttggagt
    34261 aataggaatt gaatttgaag caaaacatca atacaataca tttaaattta taagtatagt
    34321 tacaccaata atagcattat taacttgtct aatatcagca ttgattgcag tgattctatt
    34381 taaaagaata tctaatccta catatactga ttttgctaat acagattatt taacaggcct
    34441 aaaaaataga aatgcttttg aaatagatat gaataactta aacaattcaa atctaaagaa
    34501 tctaatatct atcatatcaa tagatttaga cggtttaaaa aagattaatg ataaatttgg
    34561 ccatcagaca ggagacttat atattaagca agcaagtaaa attatacaat atgtaataaa
    34621 taaaaaatat atagtttatc gtattggagg tgatgaatac ataattattc taaaaaattt
    34681 atctcacaaa gaaataaata atattataaa taatattaat ttaaaaatag ttgaagaaaa
    34741 ctcaactaat gaattaaaat tatcaatgtc tattggatat gctatttttg atgaaaaagt
    34801 agatgtttct ttatttgata catatcgtcg tgcagattct caaatgtatg ataacaaaag
    34861 gaaaattaat aaacaatatc aataataaat ttaaaaagtc tattctttaa ataataaatc
    34921 acaagaatag acttttttaa atttgtgttt ttataagata aattatttaa ttaaagtttg
    34981 ttcttttttc taaacgattc tttataaatt catatattac tttcactaat atatttgtga
    35041 ctaatattaa cacagctagt gctgctgcct gtgcagtact ccccttatca tctagttgta
    35101 caattgatat tgcagctact tttgaacttg cagtatatat aaaaactaat gctgatattg
    35161 tcaccatgga gtttaggaaa aagtacataa agttctctaa aactgctggc aaacaaagtg
    35221 gtatagttac gttcttaaga attgatgcac tgtttattcc cattgattta gctaccatat
    35281 ccaattcttt atctactttc ttaatagcag tagtagctgt tataaatgct actgaaaaga
    35341 aatgaactat attacatata accattataa gtaatgttcc atataatcca ttaaacaaat
    35401 tcttaatgta tattgtatcc ataaaattaa actctaattt attaaaaaat aatacataag
    35461 ctatacctaa aactaatcct ggcaatgcca taggcaatgt acttaaaaaa tacccaaatg
    35521 attttaaata tggagctttt tctgtttttt cattcaaata tgcaaataag aaaacaaagc
    35581 tcgtccctag aatagctgtc aatagtgaca tttttattga atttataaat ggtttaatcc
    35641 catcaatact gtttttcata gaaaaatgtt ccagtgtcag tcttaaatca tatggccaaa
    35701 ctgatattaa tgaagataag attacagtta acattacagc tattatacca aatgcaataa
    35761 ttcctacaac ccctcctaaa atactatctc ttaacttatt agttttaacc ttatatggaa
    35821 ttgactttga agttatatat gaattttgat ttttttcaat ttttttagtt actataaacg
    35881 atattattgc aggtattaaa agtaatattg atacagttgc tcccattggc atattctgtt
    35941 gccctataat ttgcttatat acatctattg ataacacatt aaactctcct cctatcacct
    36001 ttggagctcc aaaatctgta aaacataatg taaacgatac gaatgcagaa cttattaaag
    36061 agtattttat acttgggatt gttatgctta taaattctct tatcttgctt atccccatag
    36121 tattactagc ttcatatagt ctataatcgg ttgaacttag agatatataa agtatttgaa
    36181 atgattgagg aaatacatat ataatttgtg ccaatattat tcccactgct ccatatattg
    36241 gaacatgcac tccaagtaaa ttagttacca aaccttgatt tccaaataaa tatactagac
    36301 ctattgcatg catcattgtt ggagcaaaca taggaaacat agctaatgat ttaaaaaaac
    36361 ctttaaattt aatctttgtt ctagttaatg catatgcata tactaatgca agtgttagtg
    36421 atattacagt tgatataact gatacaaata ctgtattttt tagagaattt aatagagatt
    36481 cagaagccaa gtattcttga aagttttgta atcctacaaa gactccatct ttatctaaaa
    36541 aagcctgtac aaatagatat attataggtg ctaataaaaa tattactaaa gacataacta
    36601 atactgtaag catacatttt tttatatcta aattcatttt tgatttaaga cttatacttt
    36661 tagaacttat agcattatta ttcatacgct tatgctcctt taacttttgg atactttaaa
    36721 tagtattttt cgtctatact tatttttaca aggtcacctt ctactaaatt taaattaacc
    36781 cactctttta tagaaacatc acttattatg aaattttcat ttaatttatc ttttatttca
    36841 actctcaata aattccctct aaactctata tttgatatta tcccttggta gttttctttt
    36901 gtcgatttct ctatttgaac atattctggt cttacagtta atatagaatc tccattatca
    36961 aaacagtttg tatctcctat aaattgagct gtaaataggt tttgaggatt ttggtatatt
    37021 tcttctggag tccctatttg cattatatct cctccattta gaatagctat tttatctgcc
    37081 atagttatag cttcttcttg gtcatgtgtt accattattg tcgttatatt aagttctttt
    37141 tgtaatcttt taatgtccat tctaagcttg tgtctaacct ttgcatctaa tgcggacatt
    37201 ggttcatcta aaagtaaaaa ctttggttca agagctaatg ctcttgctat tgcaatcctc
    37261 tgttgttgtc cacctgataa tgctttaggg tatttatgag cttcattagt caatccaact
    37321 gtttcaagta cttccttaac tttattatct attttttctt ttgaaacttt tctctctttt
    37381 agtggaaaag ctatattgtt ataagcagtc atattcggaa ataatgcata tgattgaaat
    37441 actataccaa aacctctctt tgatggctct aaatttgtaa tatctttatc ctggagaatt
    37501 atagttccac tatttacatc ttcaagacct gctattattc taagtaatgt agttttacca
    37561 catccactag gtccgagtaa acatagaaat tccccttctt caatatccaa actaatatta
    37621 tttaaaaccc ttttttggtc ataactttta aacacattat ttatttttaa gtaactcata
    37681 tcttatctct ccttatatag ttattttttt attttaaatt ttatatccta ctttttcttc
    37741 taaaattctt tcatctaaat tattaattta aaccttactt actttcagat tttgaaccgt
    37801 attttgattc ccaagtttta agtactgtac ttctgttttt ggcagcagag tttaaatcaa
    37861 cttcttttat aagctgttca aatggttgtt tagaataacc ttttggaact ggattatctg
    37921 tctttatgga agtaactgct acttcatgtg catatctatc catagctgaa tcacttattg
    37981 cccaatctaa aaatagcttt gcttcttttt ttatattatc ttttttaact aaggcatttg
    38041 cttctaagtc ccaacctgaa ccttcctttg gaaatacaac ctctataggt tctccactag
    38101 ataattgttg tgtagctcta tatccaagtg taatacctat tggatactct ccagagccag
    38161 ctaacttcgc aggttttgaa cccgagtgtg tatatgtggc tatattttta tgtaatttat
    38221 ccatgtaatt gtaagcatct ttttcaccca tcatttgaat aagccctgat actgtaagat
    38281 accccgttcc agatgatgct ggatttggca ttgttataag tcctttatat tctggtttta
    38341 ttaaatcttc ataacttttt ggaatatcta tacctagttt cttaagttcc ttataattaa
    38401 ctactattgc tgtctctggg acactcattc ctacccaaga tacatcatct tcagtatctt
    38461 taaatttttt atcaacttta tcataatttt taggcttata tgcttcaagt gcaccatctt
    38521 tttttagctc tatcatgttc attgctgata atccccatat aatatctgct tgtgggttat
    38581 ctttttctgc taatagtttt gaagctatta caccatgaga atccataact atctctacat
    38641 ctatattggg atactcttct ctaaaacctt ccatataata agctatctgc tcttcctcta
    38701 gtgctgcata tattgtaagt ttattatttc cttttccttg agtagtttgt ggtgttgttg
    38761 atatgcaact tgtcataaat gtaatcacta caatgcacag acaagtaaat ataaattctt
    38821 tcatatcttc ccccctttgt gttttttcct ttttttattt gttttttatt gtttttgctt
    38881 atgtttatat aatacaccta atttgttaat ataaagttaa gtgtaaatta acagttcgtt
    38941 aatttttaga aatttttgtt aaatatatta tttttagtta aatacagtct gtttttaaac
    39001 aatatattaa tttttatagt atctacattt taatttaaac ataaaaaata agtctaacct
    39061 ctataaagta gaatgttaga cttattttta taagtattta attatacaac caaatcattt
    39121 tttttctttt cttcaagtgc ttttttaagc accatatcct taaccttcat aagtctagta
    39181 gtacttgctc tctcattttc ttcaagcttc atagctatat acttaatagt ctcaatgtaa
    39241 tttggtatca ttacattttc aagagcatta acacgtctac gtgtcttttc tatctcttgt
    39301 gcaagaagct gtgcactttt ttcactttct gcaagtctta aaagtggttg catagcatct
    39361 gagaaagctt ccatagcaga atctaattca cctgatgtaa aagcaagacc ataaggataa
    39421 atatcacttt gattgttttc agttttaaag tcaaacacag gaacatcaac actcattata
    39481 tttctcgtag aaacatctac tgaaactgat tgctttggca tcataagtgc tgaacccaga
    39541 tactcctgac tcataactgc tcttgcgatt ataaagtttt tataagcagt atcaagagca
    39601 ttttctgctt cttcacgcaa tcgcttattt tctcttacaa tctcaagaaa ttgtttcata
    39661 agttcatcaa gtttatcttt aagaagctta tgacctcttg tagcagtttt aaggagtttc
    39721 ttaagtctag tcatttccat acgtgttgga tttatattta atctagccac agatatcact
    39781 ccttaggcat atatttttca aaatattcat cacggatacg tttaagttca ctttttggta
    39841 acatactaag aagcttccat ccgatttcta atgtctgctc aatagttcta tcagttctaa
    39901 atccttgtga aacatattct ttctcaaatt catctgcaaa cttagcatac attaaatcaa
    39961 tctcagaaag tgcagattca ccaagtatag ccataagttc ttttgcatcc ttacctcttg
    40021 aataagctgc aaaaagctgg ttcattgtat ctgcatggtc ttcacgagtc ttacctttac
    40081 caataccttt atcttttaga cgagaaagtg atggtaaaac atctatagga ggctgtatat
    40141 cttttttata aagttcacgg ctaagtataa tttgcccttc tgtaatgtat cctgtaaggt
    40201 caggaattgg atgtgtctta tcatcctcag gcattgtaag tattggaatc atagttatag
    40261 acccttcatg ccctttcatt tttcctgctc tttcatacat agtagcaagg tcagtataaa
    40321 gatatcctgg atatccacga cgtcctggaa cttctttttt agctgctgaa acttcacgca
    40381 atgcctctgc atagtttgta atatctgtta ttataacaag tacatgcata tcttgctcga
    40441 aagcaaggta ttctgctgct gtaagtgcca ttctaggtgt agatacacgc tctacagctg
    40501 ggtcatttgc aaggtttaca aacactacag aacggtcgat tgcaccagtt gctttaaaat
    40561 cgcttataaa aaattcagca tcttcaaaag ttataccaac tgcagcaaat acaacggcga
    40621 acttagaatc agttccacgt acttttgcct gtcttgcaat ctgaactgca agattggcat
    40681 gtggcaaacc agaccctgag aatataggaa gtttttgccc tctaaccaat gtattaagtc
    40741 catctatagc agagactcca gtttgtataa actcggccgg ataatcacgt gctgctggat
    40801 ttattggagc tccatttata tcaagtcttt tatctggtat aatttctgga cctccatcaa
    40861 taggtctacc cattccacta aaaacacgac ctaatatatc tggtgaaact ccaaagtcaa
    40921 gactctttcc taaaaaacga actttacttt cagcaaggtt tatacctgtt gagctttcga
    40981 aaagctgaac aagtgcagta tctccattta cctctagaac tttgcaacgg cgaatttctc
    41041 catttgaaag ttcaatttct ccaagttcat caaattttac accttctacg ccgtttatta
    41101 acataagagg accggctacc tcttgtattg acttatattc ctttatcata gttcttcagc
    41161 ccccctcttt ttaataaggt ctgcaagctc gttgtctatt tcatcttcaa ttgaatcgta
    41221 agctgcatct atatcgcctt cttctacata cttagcacga ccaatctttt caagaactga
    41281 aagcttgata atatcgttta tagtaacatt ttgcttgata gcatcttgtg ctgacttata
    41341 gaattttaat ataagtccca tcattctata ttgtttatga agtgatgtat aagtatcaac
    41401 ttcatggaaa gagttttgat gaaggaagtc ttctcttata gaacgagtaa cctctagtat
    41461 caatctatct ccatctgaaa gtgaatcaac accaaccaat tgaactattt cttgaagttc
    41521 agattcaact tgtaaaagtt tcatagcttg agctctttga gctgagaaat tatcatttac
    41581 atttttatct gcccatacat caactttttc ctgatagagt gaataactag tcaaccagtt
    41641 aattgctggg aaatgacgtt tatatgctaa agatgcatca agaccccaga atacttttac
    41701 tatacgaagc gttgcttggc tgacaggttc tgatgtatca ccaccaggag gagaaactgc
    41761 accaattgct gtaagtgttc cttctctttc atccatacct agacaattta cctttcctgc
    41821 tctctcatag aattgagcaa gacgtgaacc taagtatgca ggataacctt cttcaccagg
    41881 catctcctct aaacgaccac tcatctctct aagagcctca gcccatcttg atgtagagtc
    41941 tgccataagt gcaacactat atcccatatc tctaaaatat tcagctattg taataccagt
    42001 gtatatagaa gcttcacgtg cagcaaccgg catatctgat gtatttgcta taagcacagt
    42061 tctttgcata agtgactcgc ctgttcttgg gtcttttaat tcaggaaatt caagaagaac
    42121 atctgtcatt tcatttccac gctcgccaca gcctatatat acaactatat ctgcatctgc
    42181 ccatttagca agctgatgct gtgtaacagt ttttccactt ccaaaaggtc ccggtatagc
    42241 tgctacccca ccttttgtga ttgggaaaaa tgtatctata actctttgac ctgtaacaag
    42301 aagtgaatct ggtgttttct tttctctata tggtctttct tttctaactg gccatttttg
    42361 catcatagtt acaggtatat cattaccttt ttcatctgta ataacacaaa ctgtatcttc
    42421 aacagtaaat tcaccagaat atatttcttt tatagtaccc ttaactccat aaggaaccat
    42481 aattttacat tctactactg ctgtttcttg aacgccacca attatatctc ctgctacaac
    42541 cttatcacca acagattttt taggtttaaa ttcccactta gttgttctat caagtgaaga
    42601 tacttcaaca cctttagtta tattagtacc tgaaatatca tacatttttt caagtggacg
    42661 ttgaatacca tcataaatag ttgaaataag acctggtcca agttcaacac tcataggcat
    42721 tccaagagaa actacttctt cccctggtcc tagaccggaa gtttcctcat aaacctgtat
    42781 agaagcttta tctccatgta tttctataat ctcgcctata agatgtttat ctgaaactct
    42841 tacgacgtca aacatattcg catctctcat gccctccgct acaacaagcg gtcctgacac
    42901 ctttacaatt gtgcctgttt tcatattctc tcacctgcaa tcatatactt tatcaaaatt
    42961 taaatattcc ctcctatatt ttattagtac atatatttag caccaataaa atttgagatt
    43021 gtcttttatt caactttcat ctattcttta aataatatat ctgcacctat agcacgttta
    43081 ctagattctc ttacttcatt catacctaat cccatacttc ctccaatacc tggaataact
    43141 ataatggcag gaagttggta atctttgtat tttgctattg attcttttgc aagcaatgat
    43201 gcctgttctg taatataaat tatcgcatat tcatcttcaa ccaacttatg tatacttttt
    43261 ttaatttcgt cactatcata ggctgggaag atatctattc caagagctaa aaatcccatg
    43321 atgctatctt tatctccaac tactcctacc ttatacataa gcatccctta gcctttcttt
    43381 tatagtatct gcgtctatat tattaagctt actagtcaaa ataattctaa ttgtttttat
    43441 ctctgattct ttagcatata aatatgcaat tagtggttct aatgtaagag gcttaaattt
    43501 tgctcctcta acatattcca taagatagtc atcacaaagt ttttcaaaga cagtaaaacc
    43561 actatccatg ccatttttac agacatcaga gtaagaagta gatttaaaac atgatgctgg
    43621 agtatctgag gaaaaagctt ctaagaattt ttccttatca agtgagccac ctgaaacaaa
    43681 cacattcata aacatatcaa aatctttctt catatttttg actcttataa aactctttag
    43741 atttgttaaa tcacaaactt tcataacata atctattaca aatttgtttt ggctttcttt
    43801 agcagtttct ttcatactgg taaaggttgc tttatctaga acaatatcaa ccatctggcc
    43861 attttgtgtc ttattataaa catcaaatgc ctctaatata gctgatgaca ttatcttagg
    43921 taaatcacta aaactacgat ttgctaaaga ttctctaagc ttaataagag gaattgtacc
    43981 tccatcaatt aaatatttct caccatctac accagaaatt tcttctttaa tcagcacttt
    44041 taaattgtga tagtcatttt tataaagaaa tacatcaaca aatttttctt caggagctag
    44101 acttttaaga atttcatatg tctttgataa ttcttgagtc aaaatattct caaaattatg
    44161 tatattatta tttgatgtat cagcataacc tgcctcagct ataattctta aagagtcttc
    44221 agggcttttg gcttctgcca tttgaataaa catttgtctg ttaagaagct gtttttcaag
    44281 cactcttatt cgtgcaacgg catagggata agttttttct tctgccattt tttaacccct
    44341 ccttaattaa acaaaatttc tgctgcaatt tgttcaatat attcatgctc tactgcaatt
    44401 atggcttcaa atgaataatt gtactcaatg tcaccttttt taactatgaa acctccagta
    44461 atatctctag tttcatcaga cactttaatg cctttttttg atagcacatc ttttaatgtt
    44521 tttttatctt ttttagataa tactatctct gaatcatctg tacaatttga tttttcaatc
    44581 atgtttagta taatctcttc atattcatta tctttaagat ttaaaagttt gtttttagct
    44641 tctaaaatta cctcttctaa aatctcttgt ttttttgata atatttgctt tttagcctcc
    44701 atataagctc ctgatatttc cttagaagcc gctttttctg cttctgcctc tgcaagcttt
    44761 gtataggaag ccatttcctt ttcagctttt tcattagctg aatttacttt taaatctgct
    44821 tcacttttag ctttatccaa tatttcttgt gcttcttgtt tggcatcagc tataattctg
    44881 tcaatcattt tttgttcatt acccatagga gtgcttcctc cttttcattt tttttactta
    44941 tgaattataa tttataatta accaattgca attccattgt aagctaagaa agaaacaagt
    45001 agtcctaaaa gagcatatgt ttcaactatt gctgcaaatg ttatagcttt accaagttct
    45061 tcaggtcttt ttgcaactat tccaactcct gctgctgctg ctttaccttg tgctatacct
    45121 gatactaaac caactaaacc aattggaagt cctgccataa gaagttgtaa accttgagct
    45181 gatgttggta ttgcatctcc accaataatc cctgcttttg ataaaataag gaaagctatg
    45241 ataaatccat acagaccttg tgtaccagga agaagttgta aaactagaag ttgaccgaat
    45301 ttactagggt cttctgttac aacacctgct gcggcttgac ctgctattga agtaccttta
    45361 gcagaaccca tacctgcaaa taatgctgct atagcagctc ctgatattgc caaaaattga
    45421 ccatttccta acgcgtttaa aaattccata tttacatctc ctttttatta atgcttgtat
    45481 attttgtttt atacttaaac ggaacaaaag gaactcctcc gccttcataa aacttattga
    45541 aaaattctac atactgtaac ctacttgtat gaacatatgc acctagtgca tttataagaa
    45601 ggtttattgt gtgtcctaca acaccaatta caactgcaag tatcggacca gctatagctc
    45661 ctaaaaggtt gataacttgt gctataactc ctgttgttaa acaaagcgcc ataattcttg
    45721 tataagataa tatatcagca aaataacttg ttataccata gagacttgaa aatcctttaa
    45781 aaagcttaac aggaatacct ttaaagcttc ttccttgagt aagtacaaga cctatagcac
    45841 ctataattgc taaatatttt cctacttctg aaaatacacc tatgtcccct gcaacaaaag
    45901 gtattataag tagacataca cctgttatac acaaatacca aaaacctatg tcaaagattg
    45961 catctattac ctttccactt cttattaatg tatatgcttt tattcccaaa cctacatata
    46021 tatggataat accgaacagt aacgacattc ccataagtgt cataacatcc tctaaaggat
    46081 taattaatgc ttttatagga attaaatccc ccaaaatacc cccgaatata agaccccata
    46141 cagtagttga aactccacag ataccaataa gtttaattaa atttccttca cctttttgta
    46201 tctttaattt atatacaaca aatccacaaa ctactgcaat tattaaccca tatgcggcgt
    46261 cacttagcat cattccaaag aatacaacaa agaagaaagt taaaattgta tttgggtcaa
    46321 tatcttttgt acttggatag ctgtacatgt tagttacact ttcaaaaggt gttactaatt
    46381 tattgttttc aagcagaatt gggaagcctt cttctttact tccttcttca gtctgaacac
    46441 aacaatcaaa cttttctgta atttctttaa ttaattcatc tgcccttttg cttggtaacc
    46501 aaccattaag acagaatgtt gtttttgttt tgacaagtct ctctataatc tttttttggt
    46561 ctctttctat agtgtaaaaa tcatataggt tttcaagcat gtgtatacta tctgcatgtc
    46621 ttttaatttc ctctgttttg tccttagaaa cgttttcctg tctaattatc atttcattgt
    46681 atttcttgat agcttgtaac ggtgtacctt cttcatttgg taatgaaacc actgaaaaat
    46741 taaattcttt taaaacttct aaaacatcat caaaagtttc ttttaaagta attaaataaa
    46801 catagttcat taacttgtca gaattgacaa tcccaataac actttctggt atttcatctt
    46861 ctaattttac tcttaaagca tcaatgtttg cgcttatggg cacagttcca agtatagttt
    46921 ttgtatactt agtttccata ttttcaatag gaatatcaaa gttcacccat ggttctaaca
    46981 tacttttatt gttgttaagt aagtttatgt tagaccttat tgtacctatc tccttgtgca
    47041 aattgtttaa ctccagagct tcagcataaa cttgcccttc tttttcacta tcaattttgt
    47101 taaactctct ttttggtgca agtagggatt ttttttgttt cactagtgaa gaaacaatat
    47161 taattgcttg gtttacatga gacattttct gctctagcat tataacttca gattcttcac
    47221 tatcttttac aagataattt tttaattcct cctcctcagt aagaaaggca ctatcatcaa
    47281 tctgaacaaa cccacggttc ataagtagct ttaaaatctg gcttttttga gcttctaagc
    47341 caacaataga tattttgttc atattaacta ttgccatatt atctcactac ctttccaata
    47401 accgcttcaa tagccttact ttttctttct tcagcagttt tttcaatttt cagacattca
    47461 cttttagcat tagctaagat tttatcaacc tctgctctac tgtcggtgac tgccttctca
    47521 ataagagttt cttccataag ctttgcttgt ttttttacat cagcaaatat gctttcacat
    47581 ttgtttacag catcagctct gatagactct gcatcagtaa cagcttttac tttgatactg
    47641 tctgctgtct gctctgcctc aacaatgctt tttattattt caaaagccat ccaaatcacc
    47701 tctcttacct ttttactatg tatataacca attagatttt tttattctaa ttagattact
    47761 acctcattgt taaagtataa acagcatttt tatataataa ttaatatttt tcaacgttta
    47821 tttcttaata aaacatattt tagaatagta cttgcctaga tttacatcct tttttgactt
    47881 acttttagac tatgacatga gtatggtttt taaataccat tattttcaat aattataatt
    47941 taaagcgata tagtttgtca atagcgttat tttgttttaa aattaacgtt atgtcgacat
    48001 tttaaatttt tattttattt tttttataat tttaatttaa tttattacat ataaaagttt
    48061 tttatattct ttttcaacct ttaaccattg aagtttattg ttttttttga atttttagaa
    48121 atatctcgca ctattttatc taacttttat aaatcatcaa gctatatcga tttttgtcac
    48181 cttattttta atctaatttt tttatatcta gttagaaata aatcaatatt tttaaagatt
    48241 gataaaactt acacctagtt ctaatagttt tattttaagg caatgtatta atcttaagta
    48301 gataatatca ttagttactc tatatattcg acaacattat aaaaaaatcc tcgtaccaat
    48361 cactccaatc ttcaatagga tatgctgctc ctccatttac acttttcagt agattggatg
    48421 tatattcttc tcccatagaa aaaagttccc ctactgtcat atcataacct ctagatgtaa
    48481 caaccttaca aaatgaatcc ataacatcac gttgttctct tgtttttata agttcctttc
    48541 taaattcatc atcattctta gcttcttcta aaattttagt taatttttca ttcattatgt
    48601 atttctcctt ttaagtagtc tttctgtaaa cttcaataag ctttatataa aaaggaagcc
    48661 atcctaaata aactaagatg acttcgctta actgttagca acacatttac tagtataaaa
    48721 taattggtgt acctggttct atattttcat atattttctt tgccttagaa aaaggtgtat
    48781 ttacacatcc atgtgaacct gaagacttat atatacttcc accaaaagaa tttctccaag
    48841 tagcatcatg aatgcctatg ttcccattaa atggaagcca ataacttaca ggtgaactgt
    48901 aaccttgacc agttaatgaa acatttctag ccttataatt aagaggatat atacctgatg
    48961 gtgtagcaaa tcctctagct aaatcacctg ttacaacgtc tgttgataca agcatttctc
    49021 catttttaaa gaaccacata tgttggccag aaagactaat ctctacatat gtatttccaa
    49081 tatcatcttt attacgagat acagcttttt gtatgtaaat aggttctctt gtaacatttt
    49141 taccagcttt tacaacatca actaatgctt cagcttcttt ctttttatct atcaaccaac
    49201 cataaattcc acctgaaatt gtaatatctt tacctgtggc agttttaaat ggtcttgagt
    49261 caccaaaagt actgtatttt ttacttaaac ctcttgtata ttctaccata gcatcattat
    49321 caaaagttat gtcataattc ttttctgagt ctacttttaa ccatttatta atttcagaac
    49381 catctaaagt ttccttacgg tcactaaaat catatgtaac gactacacca acatacttat
    49441 ctaatgtctt aatagcttgt ttcaactttt ctgaatcctt tgtgttgttt ggtgcttcat
    49501 aaactttact ttcatccaga gaaatagaag tattcccaga attaattgag ttttgtacta
    49561 acttataaaa atcatctttt ttcactttgt ttccaagtac ctctggtact ataacataag
    49621 cgtttttagt gctatcatac ttaggataag cactcttagg ttctacaaca tttttactat
    49681 caaaacaaga taaagcatta aacctttttt ctagtaaatc tttattatat gaaagagtta
    49741 tcatattatt atactcttta gatttaaata ttccaccaat ccatccaata gcgctctgac
    49801 tatcttttat cttttgaact ttatcatctg gtgtaaattt taaatcaata tcttttgctt
    49861 ttatttgttc tttcttattg tttctttcct ctaagtttaa agtataggaa ttagtactag
    49921 atgctaacaa atcatttact tgctcaactg tttttcctga agcctttacg ccattaatag
    49981 tcgttccaaa gtaaaaatga tttctaaaaa agattgccat tcctatataa gctacaaaca
    50041 aaacacctac tactatagct atcttaaatt ttagattttt ttgtccactt tcttgtttta
    50101 cctcttttcc atcaatcata attaaatcct tccttacatt gtaattacct atgtacctta
    50161 ttggttttta aacaaaacca tgtatgcctt attttatata cccaaattac tgtatcatta
    50221 tttatatttt taaatatata gttatttcta taaaaccatt ttatctttta gataaaatga
    50281 ttattataaa tccccccttt caaaatccct taaacacaat ctctgctata ttaatatatt
    50341 accatacttt taataatcgt gggactatct atctattttt gtaacactaa actactattt
    50401 taaaaaagaa actaattttg tgttagtttc tttatcttaa cttattttta tattgaattt
    50461 tagcttaaca taacgttgtt atatagattc tatttaatta ttttagtttc tatatctttt
    50521 ccatctgcat attctttaag taattcctta gcatatccaa aatattcttc aatatcagat
    50581 tcttgactaa aagaaaatat acaaattaat atttcatttg catcttctgt tatcattgct
    50641 ctttcagaat cactagttgg actcccaaat ttacccactg aatcagacaa tataggaaga
    50701 ttttctatat ttattaattc tttcccaatg cccttatact gttctccttc atctcctaca
    50761 gtaaaacata ctggtgaatg taatttgctt acattatatg tacctactgg atataatgat
    50821 tttattgata ttaaattgtt tatttctact atattattta ttgtataaag acccttccct
    50881 tgaataattc ttctaaccaa tgcttccgaa gatgttctat atctacttgg attttttcca
    50941 agctctttat aagcatttct tgcatcttta attttatcta gtttcgtaat gtcttcaact
    51001 tttagacttt gatttatagt atcacaaaac tcatttattt cattaattaa tttttctgag
    51061 cttttattta ctgctacttt tgcttgaatg caacccagct tagcattagg ccatctttcc
    51121 ttaagtttgt catcaatact tacatctatc atacttaaac aactcctata cactaaattt
    51181 ttattaaagt ttttatcatc tatacattat agtactattc ttttgttaat aacatgttta
    51241 ttagcaaaat aaatttattt ttaatataat ttttataaaa tacaattatt ttttgcttta
    51301 tattagacaa tacattgata aaataaaaaa acactaatta tttagcaatg atttattaaa
    51361 atcaagcatt cataatagtg ctttatataa aaatcaaatt ttgttttaaa gtaaatctaa
    51421 aaaattctta gctggcattg gtcgtgcaaa ataaaatcct tgaactaaat cacatccaaa
    51481 ttgtttcatt aactcagctt gttctttact ctcaacacct tctataatta caactaaatc
    51541 tagtgatttt gctagagaca ctattgattt tgctatattg cgacttctct catcatgttc
    51601 aatgccacca agaaaagact tatctagttt caatatatca attggcatat ctcttaaaca
    51661 actaatagaa gaatatcctg tgccaaagtc atccatagaa atagaaaatc catgcttcct
    51721 caattcattt aaaacattct ttaaaatatt taactcatta atagccacag tttctgttat
    51781 ctctatttca atgaaatctg aacttagatt atacatttgt attgttttat tgataaattt
    51841 tacaatatct ggttgataca actcgactct agataaattt actgaaactg gaactatctt
    51901 tttaccttgc tttttccatt cagataaatc attgcaaacc ctttcaaata caaatctccc
    51961 aatttttaaa atcaacttac ttttctctgc tattggaata aatactgcgg gacttataaa
    52021 accatgttct ggatgattcc atcttattag tgcttcactc cctatcattt ctccagttac
    52081 aagtgaaaac ttaggttgat aatacacttc aaattgattt tttaccaatg ctatttttat
    52141 atcatctaaa atcattgatt cttcactaag cttattccta acatcttcat tataaatagc
    52201 ataatttata tttttacctt tagcaacaga cctagccata tttgctttat ttacagcctt
    52261 ttgaatatct acttcacctt cttcaacaaa ataaataccc acacacagag agatttcaaa
    52321 gactatactc aaattacttt caatattact tcgtatatta tcaagttttc ttataatttt
    52381 atttcttcca tttttataat cacagaaaat tgcaaaataa tcacttgaaa gtcgtgcata
    52441 tacctcacct tctgttaatt cttcttttaa agcttttgct attgtaatta ataaattgtc
    52501 accaaattca tatccaaaag tatcattaat catcttaaag ttattaatat caaaatatac
    52561 tataatataa tttaaagatg gtttatctaa aagatactta ctacactctc tataaaattt
    52621 attttgattt cctatatatg taactttatc ttcataagcc aaacttaata tttctttttc
    52681 attagatttt tttatataaa ttatataaaa aataattgca acaaatatta atacaataga
    52741 taacactgca tatacagctc tgttgattat ttgttttgaa ttactaaata caacagtttc
    52801 tggaattgaa aaaattaaat tccagtcttt tatataatta ttttcactat tcccattatc
    52861 catagtggca taccctaaat atcttctttc ttccaacata tttaatacag ttgcacctgt
    52921 tttattttct tgcaattctt tttttaatct atttacttct tgaatatcat tatcctgttc
    52981 taacaattta taaatatttt ttgataggct atccccttgt ggatgaagga taattgtacc
    53041 atcatttttt acaacataag atatactatt attttcataa aaagatatat taataagttt
    53101 catcagagta ttgatattgt aagtacaata taaaactcca actactttat cattatttaa
    53161 taatggtact gaaatagcaa tcttctttat agacttattt acttcatcaa catatggact
    53221 tgaaacatac ttcttacctt taattgagtt tttgaaaaat tctctatctt tcactgaaaa
    53281 cttatcacct ttggtatttt cagcattacc atttatatca actattgcca tagtgtaaaa
    53341 tttttgattt tccatttcat ttaaaagatt tttcattttt tcctcattag gtatatctgg
    53401 atttgaagca taatagttag aaaaaatatt taaaacatct aaatcttttt caatttgtct
    53461 ttgtgctagt tgagagcctt gtactgcaac ctcttttata tgtatttttg cctctgacat
    53521 aagaagatgt tttgtatctt ctatatagat ataccccatt gtcaaaaata atgatgttaa
    53581 aaaaagaatt gtaattaatg taaaactttt atttctccct gtcattcgac tcctccccta
    53641 attagtcaat acttcatata gataatatat cctttttata ccaattcatc atttatattg
    53701 tatataacta ttcttaaatg ttacacataa aatcaacata ataaccataa aaacattctt
    53761 ttattattat aataacacta tttaattgaa ttttaaatta aagaataaaa actatccatt
    53821 ttctcaaaca aaaaaactct tatacaataa aactttgttt tatgtataag agtttttatt
    53881 ttatctattt tatagcaaac ttatcttcca taatatgaat ttaaatacat atcttttatt
    53941 tcattcataa gtggatatct tggatttgct cctgtacatt ggtcatcaaa tgcttgaatt
    54001 accatttcat ctattgaatc cataaactta gattcttcaa ctccaaactc ttttatagat
    54061 ttaggaatac caactttaag ttttaaatct tcaatagcta ccaataaact ttggaatttc
    54121 tcttcatcag aatttccttt taatcctaaa aatgaagcta tttcagcata tctctttaat
    54181 gcttctggat atttatattg agagaatgct cccattttct ttggtgcatc tgaagaatta
    54241 aatttcataa cttctgttat caaaagagca tttgcaacac catgtggtac atggtggaaa
    54301 gcacctaatt tatgagccat agagtgacaa acacccaaaa atgcatttgc aaaagccata
    54361 cctgccattg tagaagcatt tgccattttt tctctagctt ctgggtcttt tgcaccatta
    54421 tcatatgcac gtggaagata ttcaaatata ctcttaatag cttgtaaagc taatccattt
    54481 gtataatcgg ttgcaagcat agatacatat gcttctaatg catgagttaa agcatctata
    54541 ccagaagcag atgttaagct ttttggcata ttcatcatca tatcagaatc aactatagcc
    54601 atatttggca tcagttcata atctgctaat ggatatttta ctcctgtatc ttggtcagtt
    54661 ataacagcaa atggtgttac ttctgaacca gtacctgctg atgttggtat agctacaaaa
    54721 ttagcttttt cacccatttt agggaatgta tatacccttt ttcttatatc cataaatctc
    54781 atagctaggt cttggaaatc tacatctgga tgctcataca atgtccacat tatctttcct
    54841 gcatccattg cacttcctcc acctatagat attattacat ctggattaaa ttctctcata
    54901 gctttagcgc ctatcttagc acattccaaa gttgggtctg gttctacttc aaagaatgta
    54961 gtgtgcttaa tattcatttc atctaataaa tcagtaactg ctttagtata tccattattg
    55021 taaaggaatg tatctgttac aataaaagct ctcttcttat tcattacatc tttaagttct
    55081 tttaatgcta ctcctaaaca accttttttg aaataaactt tttctggtgc tctaaaccaa
    55141 agcatatttt ctctcctctc agctactgtt ttaatattaa gtaaatgctt aactcctaca
    55201 ttttcagata ctgaatttcc accccaagac ccacatccta aagtaagaga aggagctagt
    55261 ttaaaattat ataagtcccc tataccacct tgagaagaag gagtattaat taaaattcta
    55321 caagttttca tggctgaagt aaacttatca agtttttctc tttgatttac atcatcaata
    55381 tataatgaag atgtatgccc aaatccacca tcttctacta atttttctgc ttttctaact
    55441 gcatcatcaa aatcacttgc cttgtacatt gcaagtactg gtgaaagttt ctcatgagca
    55501 aaagcttctt ctatttcaac tgattctact tcacctatta aaaccttagt atctactggg
    55561 acttcaaagc ctgcaagttt tgctatagta caagctgttt gcccaactat tttagaattt
    55621 aatcctccat ttactaaaat tatatttctt attttttctg tttcatcttt atctaataaa
    55681 taagcaccac gctctttaaa ttcttttttg acttcattat atatattttc taatactata
    55741 accgattgtt cagaagcaca tatcatacca ttgtcaaaag tcttagatac aagaattgag
    55801 tttacagcag tttttatatc tgcactatca tcaattattg ctggagtatt acctgcacca
    55861 actccaatag ctggttttcc agatgaatat gctgatttaa ccattccagg acctcctgta
    55921 gcaagggtca aatccacttc tttcataaca gttgtagtta attctaaaga tggctcatct
    55981 atccatccta ttataccttc aggagctcca gctaaaacag cagcctcaag aacaactttt
    56041 gcagcctcta tagtagaatt ttttgctctt ggatgtggag agaaaattat tccatttcta
    56101 gtttttaaag ctaaaagtgc tttaaagata gcagtagaag ttggattagt tgtaggtaca
    56161 actgctgcaa taacacctat tggctcagca attttagtca taccaaatgc ttcgtctttc
    56221 tctataacac cacaagtttt agtttcttta tatgcattat atatatactc tgaggcataa
    56281 tgattcttta taaccttatc ttcagcaatt cccataccag tttctttttg tgccattata
    56341 gctagaggaa ctctttgctt attagctgcc aaagatgctg ctaaaaaaat tttatctacc
    56401 tgctcttgac tatatgtagc aaatattttt tgagcttctc tgatttttgc tagtttttta
    56461 actaagcttt caacgttatt tacagtatct aaaccaactg acataacttc attttgtttt
    56521 ttattttcta ttattacttg ttctttatga gccattttaa caacctcctg agatagtttt
    56581 ttatttatta tgttaattta ttaacattat agcatttact ttttctattt tcaagttatt
    56641 tttttaacat tttatttttt atctaatata acatcatttc tactaataat atctagcttt
    56701 acaaatactt aatttaacta gatatcactt tattttttac acaaatcact aatgaaatca
    56761 tctaaaaact taaggataac gttatttttt taacgtttat atttttgtat tttttacaaa
    56821 taaaacttta taaaaagaat ttttaatatg atactctatc aagtttaaaa ataaaaatac
    56881 ttgaaaatga aaataaaaac ttaattaaca agttaaagta aatatagtta aatgtacaaa
    56941 catttacaac atatagtata attaaaaaaa tatatattca tgatttttat atactatgaa
    57001 ataaaatata tttaatatta tatagataaa tttgaagttt ataagaagga ggataagcat
    57061 gaaaaaatta aaaacaatta gcattttttc tttgattata agtgtaattt taacgattgg
    57121 aggtattgga atagtaactt attatgtaga taatttgttt attagaggac tatcggtatt
    57181 tgttttaatt atgtcctctt cttttgtatc aacaacagtt agattgatat ttgaagagtc
    57241 aaaacgatat aaattctaat ttaaaaattg gattaagtaa ataattttaa tataccaaaa
    57301 attacggaga ttagctcaaa atagactttt tagtccatga ggcatttttt tgtatgaaat
    57361 taaatatatt ttcatcattt caacaagaaa aagaggcttc tctctatttt gagacagcct
    57421 ctttgctagt attttatcta atacataata ttataagaac caattctatt gatgtggact
    57481 ttttataaca ggctgtagct gtttgttctc tagagcaagt tctatagttg gaattattag
    57541 ctcagtatgt gcaatcatag aattaggctt tgctttgcaa ttatcttgac caaaaggtac
    57601 aaaatatata tttttagaat taaggagaat gccaatattt ttgaaattaa agcttagagc
    57661 atcattcgtt gatattgata ttactagtgg tttatcatta cgaagatgac cttttgctgc
    57721 cattaatact ggtgaatctg taataccatt tgctaatttt gcagcagtat ttccagtaca
    57781 aggagctatt attataatat cagcaattcc tttaggtcca aatggctctg cctcttcaat
    57841 cgtaactata ggtttatttc ctgtaagttc atatgctttt ttcataaact cttcagaatt
    57901 tccaaatcta caatcgatat tttgtgatac atctgaaaat atagtgtgta cattagctcc
    57961 ttctttaacc aaattctcta actctataaa tattttatca taagtacaaa acgaaccagt
    58021 aaatcctact ccaattgtaa gtccttcaag tctcatttct aatcccttct ttcatttata
    58081 atattttcta tagcgttaac aagaatttca ccagatgtct ttggtgaata tttaccagga
    58141 agcccaaggc aaagagtcgc attaatccct gcttctttaa caacagaata atctactcct
    58201 ccaggagaag aagctatatc tataatagtt acttcttgtg atactttttc taacctttct
    58261 ttcgttaaaa tacactctgg tatggtgtta aaaatataat caaattgtaa aagtttttca
    58321 tcaagttgac ttaaagaaat actggaatat ccaaatgcat tagccgtact tcttgcatca
    58381 ttatttcttg cgccaacaca tacatttgca tccaaagcgt ataatttttt tgcaagtatt
    58441 tgtgcacatc ttccataacc taatactaaa cagttacttt gatgtatatt gattatactt
    58501 cttttaatag cttctgctat agccccttca gctgtagcaa ctgcatttaa aatagcaaca
    58561 tcattcattt tcataaaatc ataaatctga atagagtgtt gctcgcaaaa tttacaaact
    58621 ttagttgata tgttacctcc aaataatatt tgattaggag ataaattaat tagcaagtta
    58681 tcaatagtag catcaagaca atcatccgta ttttcaatat taacttgatt ctttgtaaat
    58741 ggaattggac ataaaataat ggaacttttg gatagtgctt cagctagtga agttgatttt
    58801 ccaacgattc catttataat ttcatttgat atcccataag tgactacaga atacccttta
    58861 ttaattagtt tttttaccat gtacatttgt cgcaggtctc ccccaataac agttatatcg
    58921 tattgatttg acatattgta agcctccttt actatataca atatgttttt atcaatacat
    58981 tggttcacta aaattactaa atattatact tataacattt ttaataatgc taatctatct
    59041 atcttttcag aagaggtata tggaaatgaa tttaaaaaga taattttctt tgggatttca
    59101 tttttcatta gattatcttt cattttaatc aacaaatctt tcttcgtaat tttgtctata
    59161 gttattacaa ataatacaat ttgatttcct cttatagtgt ctgagtacgg caatacaatt
    59221 gcatcttcaa tttgaggaat ttttttaact tcattttcaa tcttagtaga actaacttta
    59281 aatcctccaa tatttaaaat gtcatcactt cttccttcaa atattaagta tccatcatta
    59341 tcataatatc caatatcatt gacagaataa ggtttggttg cattatatac tgcatattct
    59401 gtattcacaa aaatttttcc ttctctaata tatatatcta ttcctggaaa tggtctgcct
    59461 acacttagag gtttttcaat tagttcatca tagcataaat atgtaatata atttaattca
    59521 cttgccccat agtataaaat aatttcagac tttggcatat atttttttag atttcttgca
    59581 gtatcttcaa ataataattg agaccctgta aaaatactta caactttgag tactggttct
    59641 tttaagtgtt taaccaaaag ttgaagtttt gtaggtataa ggtatatgtt agttacatta
    59701 tattgtttta ttatccttat ccatgattta caattaagac ctgaacttat tacaatacta
    59761 cctccttcat ataatactga cattatagaa tttagattcc ctgtaaaact aagtgttcca
    59821 ttaacaaaca agattgattc cccagagata ttaaaaatac cattttgtat aggaaaaaat
    59881 ccagcccaac tctcatatgt tctatataat acctttggaa cacttgtaga acctgaagat
    59941 aaagctccca tacaaatact tttatctaaa taatttataa ggttcttata ttgatacata
    60001 tatatattaa atttaggatt aaaaatagaa aaattaactt tttttgctac ttcattattg
    60061 ttatcatcat ataaatcaat aacgtccata gattcatcag atataatgat tgaaatatta
    60121 ttttttaata aaatatcatc taatactttt ttagaaagat tataatgaca aataatagga
    60181 atattttttg aataattaat agcaaaaaaa ctaatcaact gaaacattat atttttagaa
    60241 tatattaaaa ttgggatatt ttcacctaaa gaaatttgtt ttcctagttc ctcactataa
    60301 ctcaatatat tttcataagt atatttttct ccatctataa ttaaaaaatt tttattttta
    60361 tgcctctctt tttttattct taaaagttca taatagttca taatctacac cctttcaagc
    60421 agtaaagctg aacctagacc accagctgca gctatagagc aaattccata tctaccctta
    60481 gtcttttcta atgcttttaa aagatgtaat gcaataattg cacctgaagc accatatgga
    60541 tgtccatacg ctaaagctcc accaaatata ttatatctat ctattaactc tggatatttt
    60601 ctttgaaaca acacatctat aactgcaaat gcttcattaa attcaacagc agatacatct
    60661 aaataattaa gactttctat ctctaaaagt ttatccattg cttgtatcgc tgatgttgga
    60721 cttaaggttg catctgttcc tattgtgcat gtattaataa tttttgcttt aggcttcttt
    60781 tttacatgtt ctaaatactt cttagaacat attataataa atgaagctcc atcattaata
    60841 agacatgaat ttgctgcatt tgtaatagtt tcttttccta aaattgatgg catcctatct
    60901 aataaccttt gactcatctt atcacgtata ccttcatcat aggtactatt atttatagga
    60961 gatataatat cttcaagtat tttttcctct cttgcttctt ttgctctttt atgactttcc
    61021 tttacccaaa aatccaagtc tgctttctca atttgatata actctgctac tctttccgca
    61081 ccttcgagca tactattttg gctattatca tcaggagaaa attgagcaac tgtataattt
    61141 ggattatttg tattatatcg cttatcattc ttatgatatg tgcgcattgg ttgtagagaa
    61201 ctactttcaa aaccacctgc aataattaaa tcacactgac cagatttaac ctttgaaaaa
    61261 gctatgtcta tactcatcat agcagaagca cactgcatat ccacagtaaa agcaggtact
    61321 tcatttgaca ctcctgctgt taaagtcatt aatctagcta tattccctcc tgtcccaact
    61381 gcatttccac atataatctc atcaatttta tcaatttcat actttttaat taaatctttt
    61441 aaaacacttg ctcctagtaa ttcaggttga acaaattgaa aaattccatt ttttagacct
    61501 atatgacttc tcaatcctcc taatataaaa acttcctcca tacattacac ccttccttat
    61561 attatagatt tatcatagat ttcttctgag tacattgttc agtttagtgc ctaaaaaaga
    61621 tgcaataacc gactttattg tatctccaat taaaaatggt actactgctg caaaaagtgc
    61681 tgcttctact gtcatttgat taaaatagca cataaatact gttcccataa aatatataat
    61741 aggcattcca acaaaaattg ttattagtat atatctctta atatcattgt ttcgtccttt
    61801 taataaacta ataattagtg ctgcaaacaa aaacccaaaa taaaaaccac ctgttgggct
    61861 taacaacttt ccaataccag atgtacctcc accaaatact ggaatcccaa ttaaacctat
    61921 cattatatat acaccaactg tactaaatgc ttgtcttggt gttaaaatca aagctattaa
    61981 atttatcatt attgtttgtg ctgttactcc tgctggagta aatggcaatg gtatatatat
    62041 gtaagatgat atacacaata atgctacaca tattgacatt ttagttaaat cttgaatatt
    62101 tactttagta tttttcattt ttataattcc cttcatatgt cttatttcat ttagtttata
    62161 tgtacatata caaagcttct attaaagctt tgttttagta taaaataaag acgttttttt
    62221 gtcaactatt ataattattt aggtttacat ttaatttata agtaaacttt atactgttac
    62281 tttatatttt aatagtcatt tataaaactt tgcttaaaaa cagctctatt tagactatac
    62341 ttgtaaatta taatatgata tatttttata taagatttta ttttatataa aaaatagtaa
    62401 caaatagttt atacacaaga tatttaaaag gaagtgatga tatgaaagtt aatgaaaata
    62461 atataaataa tatagatgaa gagttagatg aacttagtag gaaagtttac ttagagtcac
    62521 cagatttttg gataagtatt tctgacaaaa taatagataa agtatttgat gaaatgttat
    62581 tattttttgc agttaaatat aactatttca atatagtatg ctttgctatt gaaaacaatt
    62641 atctggattt aaacatgcct tcaaaaaaca aaaaatacac taatataatg gagcatttgt
    62701 tagatacatc aaaacagaat gaagataaaa aaatttataa ttatcttcta agcttaaata
    62761 aaggtaataa cctagatgaa agaccaattt tagatgaatt aaactgtaat attagtagtg
    62821 atacttttga aaaaaaagat atatatcttc caaagtactt atgtccaagt tgtaattcta
    62881 atatatttga tacaggttat aaagtatcaa atgacataac atataaattt tcttctaaag
    62941 aagctgaacc tattgaaatg tgtagtgaag tttcttctat cagatgttgt aattgtgatg
    63001 aattattaga agatattaca cttgataaac tatataacct atgcaaaatt caaaactgta
    63061 ataattgtgg ttctaattta actaaggtag gaattattgc aaagaaaaaa atgaactttg
    63121 atgagaatac tgaaaaattt aaagatgtct caacatttta ctgttgtgga aattgtgact
    63181 ctgaaataag cttatctcaa agagaacatt ttaagattta aatatttata ggctaaagta
    63241 ataagattac attattagat actgtataag ttttttaaat ctgtaaaaat aaatacactt
    63301 ataagaatta aaattgctat gaaactagtt cttgatgaac taatttcatg gcaattttct
    63361 ataatctaat aattattaaa ttttaacaaa cctttattag cattccataa ttatttaaaa
    63421 ttctttcaat actctatagt ttataggtga aagtatcttt aatattatat caaacttatt
    63481 atctttaaat agtaaatttg ttaaatctga aatacaccat acaattttat tttcctcttt
    63541 tgtagctata tcaattctga ttaacttaca tctataataa atatctttat cttcatatag
    63601 tctattttaa aaattactct taaaaaatca aatggcaaat aaattaatta tccttttaat
    63661 agaatgtaat catattattt actatattcc attatgtact ctttaaatcc tgaatcttca
    63721 tttacttgtt cttttactat attaaaacct tttttattat aaaacacaac tgctttttta
    63781 ttatctttat atactgctaa gcttagactt ttatattttt tagttgcata atctaaaagt
    63841 ttacctccga tacctagatt ttggtatttg ggctttataa ataaagctcc tataaatctt
    63901 ttatctatta tgcttataaa tccttttatt tcatctccat catcatatac aaatgtatct
    63961 gatataggta tatattcgtt tttaacagta ttgtagttat tttgccagta ttctttactt
    64021 ataaagtcat gtgctttgat tgtacttttt tcccatattt ccatgatttt atttatatct
    64081 ttactgttta atttctttat cataaatttt gtttcacctc atttttgtat tgattttata
    64141 atgtttgtag gtaagtgtat tttatttaga tatgatttag ttaatataag gtggatgttt
    64201 tagtatatgc tattgttgat tctacaattt tatatactgc tttattaata taaaataagt
    64261 ttctaaatac tcgttgatat tgctaatatt ctacttatct accacttagt tgatataaaa
    64321 cctgacactg tgtcttgtgt gagtcttttc tttatcctat ttacatacca cttagttaat
    64381 ataaaacttt tcatttaagg aactcctgtg ttataattat attatttaca taccacttag
    64441 ttaatataaa actgggtatt atggtggaag aacagaggtt tttaaaccta tttacatacc
    64501 acttagttaa tataaaacaa attcaacaga aacaagttcc gaattgtatt tctaatttac
    64561 ataccactta gttaatataa aacgtgatat tggtacatat agagaaaaag ctaaaaaata
    64621 atttacatac cacttagtta atataaaacc agttgaaaat gcaactaaaa aaataaaaat
    64681 gaaaaaattt acataccact tagttaatat aaaaccccaa aataggtata tttgaataca
    64741 ttgaaaacac ttcaatcaag caattataat tcaataaaaa catcaaaatt tgcagtgagc
    64801 gagcagtagt gcaattgata acagttatca tacaccttca atcccttata ttccaactgt
    64861 taacacctat tttagcataa atatcgctca ctgcaaacct atataaacat ttcatcagaa
    64921 tacttatcaa tcccataaca tttcttttta attgaattag gattttttat ctcataaaca
    64981 tagattgaat cctcgctatt atcaataata ttttctattt cagaaataca tttatgtaac
    65041 tttccttcag taatattgcc ttcaaaaaca gaattttgcg tccaagtcaa atattttcta
    65101 agtatccttc taattctatt taacgacctt gcttcaacaa tatcataagt aacaataaca
    65161 aacatactta ccaccacacc tttaaaactt tgtacctttc atcatttata aaatgtttaa
    65221 ttaatttata acactctaac cttataaaca ttctatatga aacttttcta tttagatttc
    65281 tatgttttat agttgtctgc atcttatttt caaattcttg caaaaatttc ttctttcctt
    65341 tttcacttaa ataacaaatt ttgtcttgat attcaaaatc attcttatta attcttttat
    65401 tattaatcag gctaaaaatt attgtgtcaa ttataattgg cttaaaaatt tctgcaatat
    65461 ctaaacttaa agaaaatctc tttgttgatg gttcatgtaa aaagcttatt gtagggtcaa
    65521 gttgtgtctt atatatctca cttaaaacat tcgtatacat tatgctattt ccaaaagaca
    65581 taagagcatt tactgggtct ttgggaggtc ttttttctct tttataaaat tcaaaatcat
    65641 cttttaatat ttgattaaat gatttatagt atgtttttct tattctgcct tctttaccca
    65701 taagttctga tatttctttg acatcattca aatcatttag ttcatccttt atagtatcaa
    65761 ttaaactttc atcaactttg taatatctca tatttcttaa aatatggtat gatgcacttt
    65821 ccacaaagga ttttgctaag tataatcttt catttttatc taaatagcag gctgattgac
    65881 atactaaact gaatcctgat acatttttct tccttggata atatgtacct gaataatatc
    65941 catagtaatt gtagaaatga agcatcaccc catatttact tatgtaattt ataagttttg
    66001 tgtttaaatc tacttctcca tatatatgaa tatcatcaac ttgttctact ggtaatattt
    66061 ttttctcacc ttctaaattg taatagtaaa tcgtattttc tttccttttt atatccccat
    66121 tacttataat ataatagtct ttatacattg ttactcctcc ttcacaaaac aaaattcata
    66181 ataagcacat tttgtacaat aatgtttttt ctcaattttg ggaggagata actgcatatt
    66241 tatttcattt atatttataa gtgtgttttc aataattctt tctttttctt ctgtcaatat
    66301 caattcttct tgtttctttt ccttaacata atttatagtt ccttttttct ctatacccat
    66361 actattcttt aaatagtata agtaatagta taactgcatt tcatctgctt ctttcatctt
    66421 tgaacttatt tttacttctt ttacatactc gtcctttatt atatctagct tcaagatatc
    66481 atcaatcaat atttctttat ttttcattct tttatatgaa tcttcatgta ctatcttccc
    66541 agacaatact ctactactat tttgttccat ggttattcct ttagaaaata gccataattt
    66601 tcttttacat acataataat aatttatttt tacaccttga acttttaata cttctaaatc
    66661 tattggcaca aaatcacctt ctttagtaaa ttttagccac attgttaata taaaaatcaa
    66721 ataaattggt ctatttcatt acttataagc acacctttac caaatatctg ttttgtatgc
    66781 ttattttcgt atatatcata tttatataaa agtattttta aatcttcaag acctttcacc
    66841 tgtatgtcaa ttacattttg tttagcttta tatattggta aatttacagt ttttttaatt
    66901 atctctcttc ttgctttttt tctcttagac tttattttat ttatcaattg tctatcatca
    66961 ttactatatg catttataag ctcttgtccc aactcttcat aatctttgat taaagtttct
    67021 tcaattttat tatatatatc ctctggaatt actgtatatc cttcaatatt tctaagtata
    67081 ttttgtgcat ctttagaacc taaactatat ggcgttatag tatctaaaat atttaaagca
    67141 ctggtaaatc tcttttcaaa agctgtacct tctagacttt ctttagagta tagtatctta
    67201 accatttcta ccttatattt ttctttcatc ttcacacatt cttttccatt tataaaagtt
    67261 ttcagtagct caagtccttt ttctacaata tccttatcat aaatactacc tattcctgta
    67321 gctttttctg tatatataaa tatatttggg ctattttctt catactcacg acttctataa
    67381 catctaccaa atcgttgaaa tagactgtca agtgttgaat tttctgtatg aagctcatca
    67441 aaatcaatat caagagatgc ttccactaat tgtgtagtaa tccaaatacc attactatca
    67501 ctatctgcaa attcttttat atatttttct aattttgctc tatcttcttg tatatacata
    67561 gaatgtaaaa gatttaagtt gacatctatt ccttttggct taactatttc ttctattaac
    67621 tcatattttt ctacagcact tttaactgta tttactatta caagaacttt tttattcatt
    67681 ccattttgta ttattttacc taagttttca tctattgaat tttctacaat agacacacaa
    67741 tgtcttattt tttctgtgtt acatgtcaag tcagctaagt tactattcat tacacctctt
    67801 ttttttaatt catctatata tatggttggc atagtagctg tcattatcat aaatctgcca
    67861 cctatcttat gtatcatttc tatacctttt accaatacag ctgctatttc tggtgaatat
    67921 gcttgtatct catctattac tacttttgaa tatgctaatg ttgagtacac tttttcatag
    67981 cctctataca aaaaaggaaa tttaaatatt tggtctattg tggaaaatgt cagtttacaa
    68041 gataataact ttgctaaatc tacaatctca tttgaatttt cctgattact ttcttctaaa
    68101 taatctattg ctgttgaatg taacagacct aagaatgtat catttgcttc tcctactcca
    68161 attatatttt tagccctatc aaataacgca tttatactta ctcttaatgg tagtgtaaaa
    68221 aatgctttat ccttatctat ccaaatcaaa gcagtttctg tttttcccat ccctgtagat
    68281 gcaattagta ttatattctt gtttctattc gatttagcaa atgactgaac ttctcttaaa
    68341 ctaccaaact cttttactaa atgtttttct gtgtattcgc ctatattcat attactattg
    68401 cactctacaa tctcatgggc agaagcactg tggtctaatc tatgtagcat tccttttaac
    68461 ataatatata aattatagta cttgtgattt ttatctattc ttttttctac actttgtaga
    68521 tatactttac tcaatttttc tgtttttatt ggatatctaa ctttaaattc atgctgtagt
    68581 tcataaactt tatttattaa atcttcatct aatatttttt gtattaaatt tttaaaatct
    68641 ttatctataa agatatctct ttcatgatga tatacaataa cttgatttaa tactgctcta
    68701 agttctttat tttttttcct gtctatataa ctataatcaa taaatgcagg agaaagataa
    68761 ttatggccta cattattttc taaatgagtt actattttag gttcatttat tttagtatcc
    68821 attctgcttt ttattaactc ttgaaacggt gaaaatgctt ttccaatatc atgaaattct
    68881 ataacaaagt caagtaattg ccaaaatatc tcctcttcta gaaaatctaa gctatttata
    68941 ttttttccat aactttctct taatacattc atttgtttta aaagttcatc agtatgttct
    69001 ctaagtgttt ccactggatt agatttagca tataacataa tctccctcct aatttatatt
    69061 attaaaatat aataaatctc cttcattatc taataatata tctccaattg atatagtatt
    69121 tccatcctca acataataac tatctacctt attccaaacc ctttttttat cttccacagc
    69181 attattatca tagtaattat tgagtctgta acttatacca tctatatctg tatcttgtaa
    69241 acttgttttt ggtatatata taggcattct tatattacat tctgataact tataattttc
    69301 ataatcatct aattgtatat cctcatctac ttcaaattta ttgacttcta caaatctaat
    69361 atcattaatt cttactaaat cttcttttct acctaatgat aaatgctcgt cataatttaa
    69421 taaactatca tatatttctt ccaataaatc aaaatcccca cctatatgaa ttatcaaatt
    69481 tacattcaat agcatatgac tattcattgg catagatgta atactatctt ttttataaaa
    69541 atatgttgtc tggtaattat taaatatact ttcatatgtt ccctgtacac ttatattaaa
    69601 tggtatatat tctgtagcat ttaatatttt gtgaattaat ccatttattg tagaatatgg
    69661 aggcagtgga tatgtctctg taatcttcat agcaaatggt tttttgtagc atgcagtttc
    69721 ttgaaataaa tctaatttca aaaccttcat attaattcac cccataatat tcctttactt
    69781 ctttaactag ttgtccaaaa aatttatcta cacttaaaaa attatcttca aacaatccct
    69841 taaattcttc tttatttata aataccccat ctaccattcc aacataggta aattctttta
    69901 aatcttttcc taaaaaagta ccttgaatta cttcttctat agcttgctta tttattttaa
    69961 atccattttt atctcctttt aatttaattc tacccaagaa aaatggattt gctatttcat
    70021 atactcctcc tactacaaat agaggagata aattttcttg tctacctcta atatttctat
    70081 tcaatacttt tattatttct aaaaattcta ctactcttct acatttctct ttattatcaa
    70141 gttctatctc tccatccttg cctattttag ataaatctat agtcactgta tatgtatagt
    70201 aacttaaatg ttgctctatg ttagcaagat tagggtgttc tcctattcta tctgcaaatc
    70261 ctttattatt taaaaaatcc atatcacttc tatatggctc aagagaaatc gcattactta
    70321 atcttacagt agcttctcta gtcaaagaac ctcctttttt atctttctca tcttttttat
    70381 ttgttttcat atatccaaat aaatccattt cttctgattc tcttatactt atattatctt
    70441 taaattgaat agtacctttt tctttatcga caacctgtaa attccaatta aacaattctg
    70501 ctgctaatcg tactatgtca tatcttaaac actggcgaga tgcaaatgta tacatatttc
    70561 catcatctct acttaatttt tttaattctg atatattacc tatcccttca ccatagttta
    70621 aactttgagc ttgtgctatt actgtaaatg ttaaccctct tttcatctta tttttcctcc
    70681 ttttcgtttg gtagtttatc ttttccttca tattttccag aaattaatcc agatataaaa
    70741 gcatgaccta tagattcaaa gtctaaatct ttttcaattt ctatatctaa aataaatgct
    70801 ggaatctgtt tttcagctga cataaaaact cttataattg tatccataaa atcactttta
    70861 tttccgactt taactgaatt taaaagttta tagcttactc catctatttt atttttagaa
    70921 tttttattaa caaaatagtc atgtatatca caccctaaat aataaattat tttcagcttt
    70981 tcatcattct tctccaaatt tttactatcc attttatata cccccttttt gtagctattt
    71041 attaatactc ttaattggac tactctaaaa caatctattc ctgatatatt tgatttgttg
    71101 ttgctttcca tatcattttt aactttattt cttaaaatgt tattcgttat atgcttcaag
    71161 tccctatttt tcaagagtaa atctagtaca tttgatttaa gcttgtaatc atagatactt
    71221 tgtatttttt tatttgcata cttgtctgta aaaaactttg ctaaataagt tggaatatta
    71281 aaataattta ttttacattt tttagaatct atacttgctt taaattccac aaaaagtata
    71341 ttacgaagtt gccattcact ttttaatgta ttttcttcta ctatactttt tataagctga
    71401 ttaaaaggat tttcatcttt ggaatctgaa gactcacttt tttgaacttt taaactatta
    71461 tttctttcaa aaagctcatt tatacaagta tccatgttaa caaataaata aaactcattt
    71521 tcttcattaa ttaaataatt ctttcttgta taagtagccc ctgctggagt acagaacaat
    71581 attagcttac aaatatcaca tattgatggt acatacgcct gattccaaaa catattccta
    71641 gcattattgg tgcttactcc aagtggagca aaattacttt ctgagtattc atctaatatt
    71701 cccttatata aaccacacat ttcacatact tctaaactat ccatatactc ttttatatct
    71761 tctatgcttt tatttttctt tataaagttt ttatttattt ccttcataat tttttctata
    71821 gtatttatac tagacttact aacttttttt tcatttatat ccttatctat actatttaat
    71881 ctatcattta aatagttttt caacttatca tagtcattct cttctaataa atcttctaac
    71941 tctccaaaat atataatttg tcttaaataa tcattaaaca ttacctgttt taatccatct
    72001 aaatctaatt tcgccttagc aacattaaaa aaactaactt gtccaaaata attatcttga
    72061 actacatatt tataaagatt tgctgtaagc ctgtcattta ttgattttat tttaaatata
    72121 tctatagtct catctactaa agcttctaaa ctatcaaatt catcataact ttttatctta
    72181 gacatactat ctagcttctc ttttatcatg ttaaattttt cttcatcaaa ttttttaatc
    72241 ttatcatttt gttgtttcac actatcttta attttcttaa ttccatcttt gattctatca
    72301 ggcttagatt taataaaatt tatactgtaa tcaatatttt ttttaattct ttttgataca
    72361 tcatattcat ccataaagta attaaaataa tactcatgaa agttttcaag aaataagcta
    72421 tcaaattcga tataatcttc cataataaat atttcagctt gtttatctgc tttctttatt
    72481 atatttaaaa atccaactat acccatatta aaaaaccaat ctcctctata aactcttaac
    72541 ttcatttatc tcacctccat tctaaaatat ctacatctcc aaatccctga gcacgtctaa
    72601 aaccaattcc tagattgtag ataagattta aatcatcaat atcacctttc aatataaatt
    72661 tacctttgta accattaata tattgatact ctttacctgt tattttttta aattctctta
    72721 aactctcttt aactactacc tttttgagac ctatattttc aaattctaac tttcttttta
    72781 atccattccc cctataattt ttaaccactt cattagttat atagtttagt tcttctatgt
    72841 atctatcatc agttatctcc aagaattttc cttctttaga ctttacacag attggagaca
    72901 atgcattaaa tagtaccctt tcttctgtta ccttcttttc tcttgataaa tcgattctaa
    72961 ttcttgtaag ttcgtagtct ttatataaac attttttaga agtcattaac ccattgtata
    73021 tatgaaaacc caattctaaa tctggagtac ttatatttaa tattacttta tcttctataa
    73081 taaaattgtc accttcaata ctatactttt ttatataaac cgaaaatgta aaatttttag
    73141 tttttttatt attcttttct ttataatagt acatgttttt atagtaatct tcattagatt
    73201 ttcttattgc ttcttttata atactcataa agagcgaatt ataagatatt ggtatacaac
    73261 ctgtactaaa ttcaattttc attttcataa tatcacctct ctcaattaat atattaacac
    73321 tagaccgtga agtatattgg tccaagtata aattatttga aaaaatcagt aaattttttt
    73381 cattttttca atctctaaca atatatcatt tctaagtcta tctggttcta caacctcaac
    73441 ataagctccc atacttaaaa tccaactttt tatctcctca taacctctca ttttagcttt
    73501 aaacattata gatttatcat catattctat gatttgttga ttattaaccc aaactttctc
    73561 ctttataatt gttgaaaatg gatgactaat ttttataaca acattaattt cttctccctt
    73621 ataaattcct atactatttt tactatattc atcccaacta aaacttttat ctacattata
    73681 tttttcttct aaaaccttat aatctttaat cctacataat ttaaagtcta taaacttaaa
    73741 tcttttttca caaaaagcta ccatataagt atctgattta taattaaata aaccatatgg
    73801 atgaacaatt ctttcactat ttcctgaatt taatgaataa tattctatcc aaaatttgtg
    73861 ttttgtggta tatgctctaa ttatttcatt acacttattt ttttcagact cataatcaca
    73921 attacgttgt gcttgaactg taaaataatc catatatgta tcgctttttt ctcctgtatt
    73981 taatactgct tttatttttt ctacaatatt attaaattca tttttgtaaa tatcattatt
    74041 atactctaac tgtgaattta tcatatctag aattgaaact tcactatcta ataatttaat
    74101 taatgagatg ctattacatt tatctatttc ataaccacca taaatcccag gtgttgaatt
    74161 tataaatata ccagcttgct ctaaatacat cttgtaactt tttatttgcc tttcacttac
    74221 ttccaactct tctgataatt ctttgcattt cattttgcct ctgctttgaa ttaatatcat
    74281 cattctaagt gtattagcta atttactaat gagtaacccc cccctaataa cattaattga
    74341 tatttttatt atttatttct acacatatgt acatataacc tctttatatt ttatataagt
    74401 agaatttttt tataattttg acatttacca tattatattt tatatttgta caaaatttta
    74461 atagttaata caataaaaaa tattactgaa aaaataaaca tctataattc cagtaatatt
    74521 aattaatttt aaaccctttt tattatcatt taataatagt aactaaaaat tgactaaatt
    74581 taaccttatc tcttttaaat aattatttct tacaattaaa aaataaacta tttgaaccaa
    74641 gaacaagctt cccattacca aaacagctga tgatgctact tctatatcaa aagaattttt
    74701 aagtgcagta agtgcaaata ttgaatgtat aacagccact acataaggaa acaaaaatac
    74761 tattccaatc tcaattgttg aagctttttt aatctcatta tatgtcatac ccaatttatt
    74821 taactgttca tactttttct tatcaacttg gcaatccata taaaatttat tatataaaaa
    74881 actacttgtg gtaacaaaga aaattaaacc tataaatatt gctaaaaata taaatgtaga
    74941 atacattaat ttcccagttc ctatcattaa ttctttagag aaaaacaaat atggttgcat
    75001 ccctgactca ttattaaatt tattttcaaa ttctctgcat atctctatag ttttacttga
    75061 atcctctact tcaaatgcag taaatctatc cactataaat tttgattcta tactatcata
    75121 aaaattatcc tttaccacat acatattttt gtaatatgct ggcataacac attcttccac
    75181 ttgttttgcc acctttaaac ctctattccc tacaataata ttttctttga cgttcttatt
    75241 tcctggtaaa cttgatgata ataatgatat acattcatta tcttcaaaac ttataggctt
    75301 aatccctata gtttctgtaa tttctaagta cttagattct ttcataattc tgacattaaa
    75361 atcacttttc ttgggaaata cagttttaaa ttcaccatta atccttgtat agtctacatt
    75421 ctcttttttt agattatttt ctataaacat cattctttcc ttgtcttttt ctttgctatc
    75481 aggcttttta gtgtcattat gcaatgtcat tgttgaataa tatattgtgt taggatatat
    75541 taaattaatt tgacgctcta catctttcca aaaggaataa actgtaccta tagcagtaaa
    75601 tgccactgca gaagttatag ttatcaagaa aaatattcta gcattatcct ttaccttata
    75661 aatcaagttc gaaatccaaa gcatatttgt attttttcta taaaatctct tgtttaattt
    75721 tagcttcttc ataaaaaata cactaaattg agaaaagaac aagtaagttg ctactatagt
    75781 aagggatgta actggaacta agcgcagata tgttgtatat tggtcggttg aggtaatagc
    75841 attataatac gctattataa acaaacaaat acttaatata gcaagcatta gtgatgtttt
    75901 aggctctggt tttggagttt ttgtaccttt aagtaacttc aacacctgat tttctttaac
    75961 tataaaagaa gtaaatattg atgttaatac agctaaaatc ataaaataga ttaaagtaga
    76021 caatatcgca ttaaatggta tatagaattt taatggcgat aattctaaaa aagtagacat
    76081 aaccactaaa aatatctttg caaagattaa gcctattatt attccaatta cagaagatac
    76141 tatatttatt atcatatttt ctataaagat taatttcatt acttggcgct ttgatatacc
    76201 tgtaatataa agtattccaa attctttata tctactttta agaaacacac taactgaata
    76261 aaacacaaag aagaataaga atagatatgc aattatctta ctcatcttga gaccttcttt
    76321 taaataatca ggaaattgag atacatctaa atctggatga cttgtaaaca taataaaaga
    76381 aaatagcagt gaagatgata taacaatact tgctaagtat cctaaatacg ctttaatatt
    76441 tcttgaaata ttgttaatag caaactgttt tatattcatt agttatcgcc tcccaataat
    76501 gtgagtacat ccattatctc ttgataaaac tgctctctac tactaccctt atatatttca
    76561 ttatatatag acccatcttt tatgaataag attctactac agtagctcgc tgctaatggg
    76621 tcatgagtta ccatcatagt agtaacttta ttttctttat ttatcttttg aaatagctcc
    76681 attacaacct ttgatgactt tgaatctaaa ttacctgttg gttcatctgc taaaagtatt
    76741 gatggattgt taatcaatgc tctagcaata gcagtcctct gagcttgacc acctgatact
    76801 tcaaaagttc tttttcctaa taaatctttt atacctaata ttgtagatac ttcattcaat
    76861 ctctcatctt gctcttttac actgacctta tctaatgtca atggcaatac tatattttct
    76921 cctatagtta atgtatccaa taaattaaaa tcctgaaata caaaacctaa ctctcttctt
    76981 ctaaataatg caagttcctc acctcttaac aataaaggat tcttgccctt taattccata
    77041 gttcctgtgg ttggcttgtc aatagtagaa atcatattta aaagagtagt ttttccacta
    77101 ccagatggac ccataattcc tacaaattct ccatcttcta tactaaaatt tatgtcattt
    77161 aatgcgttga aaattatttt tttaccatat actttactta aattatttac agttaaaatt
    77221 ttcattattt aactatcctt cctaatttaa tttttgaaat aacatatata taattgttaa
    77281 ttataattta tcttagttta atttttatag ataataaatc tattttttct atacactaat
    77341 tatgttagta aaagctaata ctgcaagtac tacacccatg attattctgt atacagcaaa
    77401 cactctcatt ggttttttct ttaaaaaatt cacgaatttt tccataacta ttattgatac
    77461 aataaaagct actataaacc caactaccaa agcaatccac aatgttggtg tcattattga
    77521 ataatcaaat tcaaataaat cttttcctga agaagccacc atagctggta ctgctaaaaa
    77581 gaaagaaaac tcagctgctg taggagaatt aagtcctgct atccatccac ccataatagt
    77641 agatgcactc cttgacatac ctggccatgc agacaaaact tgtaatgtcc caacctttaa
    77701 agcttgtatt ggagtaattt tatctatatt atctgtggaa tgattctttt ttctaaacaa
    77761 agtttctact actaataata aaatcccacc cactataaat cctataatta cagattgtaa
    77821 attaaacaat gattttatat tatcgtaaaa tagaactcct ataatcgcaa atggtataca
    77881 acctataatt acattcattc caaatctaaa accaatcttt ccttcttttc caccagtaaa
    77941 tataaattta aaaaattcta taacgctatc ttttatcttt ttccaataaa gtactactac
    78001 tgctaatata gccccaagtt gtattacaac ctcaaacatt tcagcaaatt gccccttaaa
    78061 atctattaaa ttaccaacca aaatcatatg acctgtagat gaaactggaa taaattctgt
    78121 aagcccctct actatagcta ttatgactga tttcaatata aaaataacat ctaaactcat
    78181 caataaacat ccttcctttt ttacaaaatt tcttttttta tgttatttct cttatgttat
    78241 ttcttatatt aattgtaatt tagattagaa aatttaacta tctgcaaaca ttacacaaac
    78301 cttacatcta tgtaaggttt gcaaataaac tctcttaaat tttgattatt taactatgaa
    78361 tatttcattt aataaattgt ataataaaaa agtacaatta actaaaaacc ctattgtaac
    78421 agataattta cacctttatt aaactattta catctttatt aaagtagatt gaaacttctg
    78481 taccttttcc tacttctgat tttatactta ctttatgacc taaatcatca catacctttt
    78541 ttactagata aagacccata cctgtagatt ctccaaactt acgaccattt tctcctgtaa
    78601 aaaatgggtc aaataccctt tttaaatctt tagaaacaat tccaattcct tcatctatta
    78661 tacttaaaat tacatattta ttattttctt cagattttat agttaggtag ttactataat
    78721 ctttagaata tttcactcca tttgtaatta attgacctat tataaatttc atccatttta
    78781 catctgtata aacataagta aatttgtcta cttgaatctt aggaatcatt ccacttttta
    78841 taaataacct tttttcttca tttacaatac tagatacaat ttcatttaat ttggcttttt
    78901 caactataaa gtctttctga aaattatctg cccttgcaaa atgcatagcc atatctaacc
    78961 ctttatttaa tctatctatt tcttttctta tattttcagt tacttcttct ccctcataat
    79021 cttgaagctg aaggcttata actgatattg gtgttttcat ctgatgaatc cattggttga
    79081 tgaaagttaa atgttcacta tgtatctttt tatgctcttg tatcattgat tgatacaatt
    79141 tatgttgttg ttttaaaata actgatatat ttctccccaa gaatgagctt cctaaataca
    79201 aaaatgactc ctccaaagaa tgtactcctt tttcaaacag attatatact tctctatttt
    79261 tataatactt atatattaaa aaacataaca atataaaaga actaaataaa agaatatata
    79321 aactctctcc aaaactaata aacttcataa gattacagta aataattgtc ataactatgc
    79381 ctatataata tataaaaata taacctttat aatcttttaa aaataacttc atactttctc
    79441 cttaccaatt cttatttaat ttatatccta accctcggac agtctgaaca gcattatcta
    79501 tacctaattc ctcaaatctt ttccttatcc tgctaacatt tacatttaaa gtattttcct
    79561 ctacaaactc aatatcatcc catatctttt ctaaaagata atctctactt actacttttg
    79621 ggtatctctt gataagacat tcaatcagta taccttcttt tttagttata attagattct
    79681 caccatttaa ttctagttct aacctttctg gataaaactt taatccatct agctccacta
    79741 ttctttcgtc tattttaggt gaatattcac catataccct tcttatatga ctctttattt
    79801 ttgccattac tacatcatag taaaaaggtt ttgttatata atcatctgct ccactttcta
    79861 aagctctaat ttggtctaca ttaccatctc tagctgatat aaaaattata ggtaaattcg
    79921 actgttgcct aatacatcta caccagtaga aaccatcaaa tttaggtaaa tttacatcta
    79981 atagaactaa gtgtggctta aaactttcaa atgtaatcat tatatcatca aagttctctt
    80041 caacaatcac ttcaaatcca tatttctcaa tataatcttt aagtaatgta cttattgata
    80101 tatcatcttc cacaatatat actttataac tcatataatt cctcctaata tacctattta
    80161 ctcatcatat aacagtccaa ttttaatata ttataatctt tttacaatat ataaatttaa
    80221 tcatattact aacttcacaa ttactgactt cataagtata accatattat tatacatctt
    80281 aataaaactc tataaaaaag tatcttttta tgattaatta atcattatta tcaactaatc
    80341 attctaaaat aaattgaaat tactaattca aaatagaaaa agttacctta ataaggtaac
    80401 ttaaactttt attatatttc ttacttagta ttattttatc atagtttcta cttagcatta
    80461 tagattaatc cttttatgtt cacttttttc tcttgtaact tattttttat taagaagtct
    80521 tgtgtatctt caagcgaaga tatgtcttta tctgttatat ctaaactaaa atcataccaa
    80581 gcatataatt ctttagtttc ttcaagactt aaatcaactt ctttagctac tttttccata
    80641 gcttcatcaa aattattatt tacatattct aaagtttcct tttcaacctt cataaatctt
    80701 tcaactattt ctggatgttt ctctgcaaag tctgtgctaa cagcagttac tattatacca
    80761 tctactaaac cttcaccatt tgctacaagt ttactacctg acttcatagc tttaagagct
    80821 gctggaccag caatcaatgc agcatctacg ctgccatcag aaagagctgc tgatgcctct
    80881 ggaataccca tattaacaaa ttccacatca tccatactta atccttcttt atcaagtgct
    80941 gaaatcaata cctgatgtaa tatagtccct tttgggcctg ccaccttctt acctactaaa
    81001 tctgctgctg attttattga attattatta gtcaaaatca taaatccttt tggtgacctg
    81061 ctataagtgt ttaatatctt taactctact ccattagatg cagctattaa agctgatgta
    81121 ccacctagtg catgtaagaa gtctatttct ccagcagcta aagcttgtgt ttgctctgga
    81181 cctgtagtaa tttcgtggaa gttaactttt atattatcct ttttaaattc ctttccaaat
    81241 aaatcatcct gtttctgaat tatagaagga acatttaatg gtgattttac ataagttaaa
    81301 tttatttctg aaagtttttc tccattattt tttttagcac atccagctaa agatgctgtt
    81361 gcaagtgtta atatcgttat acctatcaat agctttttta atttcattta ctttactcct
    81421 taaaatatta ttaatttctt taaatgcctt tatttgactt cattgtcatt aaaatatctt
    81481 tttttaattt aatatagtaa tctgaagtta aatctctatt ataaccatct tctatattaa
    81541 attcttttac ttttctttcg tctgtgaaaa caactatttt cttgcctatc tttaacgctt
    81601 catcaatatc atgagttaca aatatcacgc ctttattagt tgacttatgt attcttataa
    81661 cttcattttg catatcaatc cttgtaaaat aatctaatgc cgaaaaaggc tcgtccataa
    81721 gcaacatatc tggattgaaa gaaagagctc tagctatgct tactctctgc gccatacctc
    81781 ctgacaattc atttggataa gagtttttaa atttctgcaa gttcatcatc ttaagatatt
    81841 tttctacatc aatattactt ttcctattat atttatttga tttgttcaaa ttatcatttg
    81901 tttctaagct tctaaaatta tcatttataa ttttactcct aattctttta ttgtgtttaa
    81961 attttctaag caccttgttt aaaatagtat tttttctttg attatgaaaa gctatatttt
    82021 cacttacgtt taaccaaggc attaatctac tctcctgaaa aacaaaacca acattaggtc
    82081 tatactcttt attatcatta ataaacctaa tttcaccact atttatacct tcaagtgatg
    82141 caattgctct aagcaaggta gtctttccac aaccactttc acctaaaatt actgttatat
    82201 ggtttctatc tatgtttaaa gagatatcac taagaactac atgttcttta ttgtcaactt
    82261 tataactttt atataaattt ctaattatat atccagagtc acatactaaa ttattcatat
    82321 gcttccacca tctttccctt acttaccttc ttcacaataa tcgaaaatat gtaatctgta
    82381 attattccta aaagtccaat tacgattatc cctacaataa caacatctgt tctagacatt
    82441 tcttttccat cagatatcaa gtatccaaga ccagatgaag ctgctacaag ttctgcccca
    82501 ataattgctc taaagctata tccaagagct aactttaacc caacagcaat atcaagaatg
    82561 gcatttggta ttattatttt aaatattatc tgaagctttg aaaactcaaa tactctaccc
    82621 acttcaatca gttttgagtc acaattttta atccctttca atgtgcttgt aaagattggg
    82681 aaaaaagatg ctaaaactat aattataatt tttgattcct ctcctatacc aaaccataat
    82741 ataagcattg gtattaaagc aaggggaggt gtattcctta aaaaatttat tagagattta
    82801 aagtattcgt atactccact ataaattcca aagaatatcc ctaaaggcac acctatagca
    82861 gtacttattg caaaacctat caaaactctt ttcatacttg catatacatt aataaatatt
    82921 gaaccatcac ttatcatatt taaaaatgta ctatatacct tttcaggtga tggtaatata
    82981 taatcactcc aaataccaag ataatttgta attttccata ataaaagaat tataaaaaat
    83041 atcagaacac tctttactag ccttaaaaac ttattattaa atttattgac catttacaaa
    83101 ccatctccat tattacaacc atctttacaa taaaacattt ctactatgtc atacttatct
    83161 tcaaaaccat ttcttatttt ttgtatttca cttaatattt cgtcttcact tgatacttca
    83221 agaacttttt caaaagtatc tttgaaatat cctaatggaa ttggtgattc atctattttt
    83281 ccaagtgatt ttacaccttc ttgttcagca aactctttcc atgtataaaa catagcatta
    83341 cccttatcct taaacttttc acttgcaaag tctcttaatt gtgtacatgg acaggttact
    83401 accaacatat catctttact ttttatatat ttatcgtata aaaccctaca agtccttact
    83461 aatattggtt ctatcatagg tacttcaaaa ttatttatca aattatttct ttttaaaaga
    83521 cttatacttt ctggacatct acaatccaac attgtatttt cagtcttttt tgtatactct
    83581 ttgtactgct tttttacata ttctaactgt ggttcacatt ctgttattat gtaccccttt
    83641 tttatcaaat ttgctttaat aaggtgaaac ttttctccat acattctttc tgccactgga
    83701 tttattagaa gatatttatt cataacgcct cctattattt aatattgaat attattatca
    83761 attaatagtt taaatgagca cttaaatttt gtcaatatat taattttttc ttaataaaac
    83821 aatttttatc tacatttttt aatattttaa atgaaatatt aaatagtata tgtaatttat
    83881 tttaattaat aatgcataca tcttactaat aatctataaa tattatataa taatacttat
    83941 ataattagta ttattattta atagcaacag ttattcacac taataaaagt agaaagtttt
    84001 taaaatatta tgaaacatca aatttaattt taaaattgca tcaaaaaatg aagtctcaac
    84061 agacttcact ttttataact cttataaatt attcaaaata tttatacttc cctttctact
    84121 tcaaaacgta aaaccgtctt caatgattca ggcgatactt ttctagcatc acttatataa
    84181 atttcacgat gtgtgtaaga ttttcttata agtttatttt ttttgcaaaa ttcgttcata
    84241 atgtcaaagc tttctggttc attatcatat gaacctatat gaagcatttg aacacatagc
    84301 ccttcattaa tagacccaaa tctaactttt tcaagaagat tatgaggttt tttcttcttt
    84361 actatatcag tagctttatc caacaggtct tgtgtaacaa aatctggctg acgtatcatt
    84421 atagtgtaaa ttaaatcttc tttaataagt acatctaagc ctttactttt ttctccctta
    84481 tcccatatac cttctaaagg aaaaaccgta tagtcaaaat acccttctgg tacaattcct
    84541 tttttaggca tggtttttat tgcatatgcc aaagaataaa gtactcctat tgcttcagta
    84601 aattctttag aatttgggtc tccactccct tttaacatga taaatttctg ttctggtatt
    84661 tcaactatta caggattctt tttaggtaaa tataactctt tatctctttt tctccattca
    84721 tatttcataa aaatacctcc atatatattt tatacattga tattatcacg ctaaaagtga
    84781 caacagtgtg tcataattat aaattatatt ataaaatctt catcctctaa ttcctcatac
    84841 actccttttt ggtatccatt acccttagtt gaaaaaaaat catgtgtttt ggtttcagtg
    84901 ctaagaccat ttaatacaat tggatttata gcatctacag tatatagctt ctcaaaccct
    84961 agattttcta aagctctatt tgcattgtat tttaaaaagt tcacaacctc tttttcaagc
    85021 ccactttctc tgtatataac atttgtatac tctatctcat tctccataag gctataaagt
    85081 atagaataca tcttctcttc taacatctcc ttatccattt tatcaaatga atcgtatatt
    85141 tcttgtgcta gcaatcctat atacttacca tgtaaagact catctctaag aataagcgat
    85201 attatttctc cactagctac catctttcct tgaccagata gatacaatgg ataaaagaat
    85261 cctgaataaa acaagaaact ctctaaaaat acacttgtaa ccattgatag gtataatccc
    85321 tcttgatttg tagtattttc gtattgagct aaaactaaat cagcctttct ttgtaatgtt
    85381 ggttctgttt ctatccattc aaataattca tctatttcta aattagaaag tagagtcata
    85441 aatatagaag aataactttt tgcatgtatt tcttccatag tccccataaa agacaagaca
    85501 gcttttcttt gtaggttttc tgttaaactc atcatagatg gtattccatt attcccctgt
    85561 tttgtatcca gtaatgttaa accacccaat acttttttat ataattcctt ttctttatta
    85621 cttagttcat tccatacctt tatgtcttta gaaacagata tttcttcagg aagccaaaat
    85681 tgttttacat tttgttccca aaaagcttgt gtaaatccat cttcttctct attccagtta
    85741 actgcattat gtattttatg taaattaaat gtcatatatt tctctcccta tactgaacac
    85801 actagacact catgagtatc tcttgtcatc tttgttcttg tgtaatataa acttttcaaa
    85861 ccttttttat aggcatatat gtaatgtcta gctatatctc tagttgtctt ttcatctgta
    85921 acaaacagtg ttgttgatat accttggtca acatggtttt gaactgttgc cactaaatct
    85981 atgacctttc tcatatccat cctgtatgct gattgataat acaacatatt atcatttgtt
    86041 aaaaatggca ttggatatat tgtagtagag tctccatatg ttcttacttc tactggctca
    86101 gtaattggca ttatacttga tgtagcattt tgaacataac taatgctttg agttggtgct
    86161 actgccatta aatatgcatt atatatccct ttttctttta cctcatccaa taattttgtc
    86221 cagtcttctt ttgttggtat ataaatccct tcaaataatg ctcttacctt ttctgactta
    86281 ggtagataag attgttcata gtattttgat aaaaccttgc tatttcttcc cttaacatat
    86341 tctgatttat caaatccttc aaaagtttga tttctttcta tagctatttt catagaagct
    86401 ttaattgaat agtatctaac cattgcaaaa aatacattag aaaaatctat agcatcatct
    86461 gaagtatata aaatattttc tcttactaag tatccatgta aattcatagc tcctaatcct
    86521 atagaatgag acttgctgtt actattgctt accgttggca ctggttttat atctgtgcta
    86581 tctgctacaa atgacagtgc tcttattgct gtttcaactg tactttctat agttttatta
    86641 tccattacat tagctatgtt taaagaacct aggttacaac ttatatcttg tccccattca
    86701 ttttttcctc catacccctc tatttctgaa ggtgtttgat attgaaatat ctcacaacat
    86761 aagttagaca ttttaataat tccaacatct tttaatgtat gttctctatt agctgtatct
    86821 atgtacacta catatggata tccactttct tgttgcatct gtgctatttt tgtcaacatc
    86881 tgcctaggat ttatttcttt ttttcttata tcactatcat taaccaattt atcataccac
    86941 tcatccattt ctatctcatc aagagaaact ccatatttct tatacacagt atgaggataa
    87001 aatgcatatg ctacttcatt tttttctgcc aactccataa atttatctgg tattatagct
    87061 cctaatgata atgtagcaag tcttattttt tcatctgcat ttatcttttt agtatccatc
    87121 aacaattcaa aatcaggatg gaatacagta aggtacaccg caccagaacc ttgtctagct
    87181 cccatttgat taaagtaact aaatgattgt tctaacattt tagctactcc aacaacacct
    87241 ccagctgcac cttctatatc tttgatagat tcgccagatg ctctaagttt agataaattt
    87301 agtgcaactc ctccaccaat ctttgataag tgatttgatg aagatatagc atacgatata
    87361 ccttctgtac tatcttctac agatagtaaa aaacatgata ccatttctcc agcccttttt
    87421 cttccagcat ttaaaaaagt aggtgtagct ggttgaaatt cttgttttac tattttatct
    87481 gccaagttta aagctaaatc tttatcgcca tttcctagtg tcaaagctac aattaacact
    87541 ttatcattat atgtttctaa tatttccttt ccatcattgc tctttaatgc ataattttga
    87601 taaaacttat ttgcactcat atatgattga aattcaaact tatgtttatc aatcatatca
    87661 tatatatttt taataacatc tatgctatac tgatttatta cttcttttga ataataacct
    87721 tcatctatta aatacttcaa tctttcttct aggttattaa attttctcaa ctttggctgt
    87781 ataaattctt ctatgtaact acttaaggct tccttatcct tttccaattg gtacttgcct
    87841 tgttcatttt taattatcac ttgattgtta agctctatcc aattcattat ttaccgtcct
    87901 tttaacataa tcttgtgcca taatttcact taatttgctt attatttctt ttggtactta
    87961 tcagttgaaa tcccaaaatt aatctataat tatagaaatg caataagtat ttttcaaaaa
    88021 caaaagcact acatatagtc agtgctttat ctattatata ctacatatag tatatacaca
    88081 aattttttta tatctaaact tttattactt tataattgac attattttta tttaaagaaa
    88141 tttttatcaa ctcaaatata aaacaataca agcttattat gtcctgttta aaaatttaaa
    88201 ttatctctaa atagcttaaa aatatattct gatatattga aaaaagtact ttcaagatga
    88261 tattttatat attatttaga agttttttat ttattgttat ataattaaat atatgactat
    88321 tttgctacta catatataaa aataaattta tgaaggtgat tttaatgaaa actatttcta
    88381 aacaagaatt agaaaaaaca cttgagaaac attatttatg gcttaaaaac aataatgctg
    88441 gagaaaaggc agatttaaaa gaattaagat tagaaaatat ggacttaaga ggatactgct
    88501 taagtaatat tgacttttcg tggtctgacc ttatcaattt aaatttagaa aaagcagatt
    88561 tagaaaactc tatttttaat aattcttatc tttcggattg ttcattaaaa aattctatat
    88621 taaaaaatgc agacttaagt ggtgcaagtt ttagattttg tgacttatct aactcagata
    88681 ttagaggagc taatttagaa aattcaaatt tagaacatgc tactttaaat ggagtaatat
    88741 cagatgaaag tacccgtttt tttaaattgt attgtcctga aacaggagca tttataggct
    88801 ataaaaaatg ttttaatttt agaatggtac aattattaat acccagcgac gcaaaaagag
    88861 tgtctgctac atcaaacgct tgtagatgtg ataaggcaaa agtactgtca attactagta
    88921 tagatggtaa agaatctttt aaaagtgctc gtgcatatgc tgatgaaaat tttatatata
    88981 gagtaggaga aacgattgta gctgaagatt ttaatgaaaa tagatggaaa gaatcgacta
    89041 cagggattca ctttttttta actagagagg aagctattgg ttatctataa aatgctaaag
    89101 ttttataaat atataaatac ataaacaaaa taacaaaaga gtatagattg taatttcaaa
    89161 aaaattataa tctatactct tttttctata gcacataagt acattttatt tcataaatta
    89221 taataaatta tttatatctg cactattgat tatttgagaa actttatcta tatgttctat
    89281 cttactatcc aaactgtcat aatacttctt actctcatct ctatttctaa aagaataaac
    89341 ttttttatcc aattttaaag cctcttttat aatatctata ttcctcttat ttgtctctcc
    89401 tacactaaat cctgtatcta ttataatctt ggaatcattt aaatttctaa tagccaaatc
    89461 gaaactctca tcacttatag gctcaaatgg attttctgta aacatcttta tccccatagt
    89521 tctaccaatt tcataatcaa tatcattttc atgtattatt ccagaataca gacctatacc
    89581 ttttttagta aaagctctat aaattggtgt tgctttaccc ccaccaccaa ttataaaaac
    89641 ttcattttta gatttattac taatttctac tgaacctaaa agactattaa agtttttatc
    89701 atccaattca taaagcgaat ttataatatc ctcatctact acatcttcag gctgaccata
    89761 agctatgact ttattatttt ttataagagc aactttatca caacttttta atgctatgtc
    89821 tatttcatgc aatgaaagta ttactgatat tgacttttct ttacttaatt ttttcagtat
    89881 gtttatgagt tccaatctat gttttatatc caagtgagtt gtaggctcat ctaatataat
    89941 tatttctggt tcttgaacaa gagcccttgc aaccaacacc ttttgttttt ctccatcact
    90001 tagttcatca aaatatcttt tctttaaatg taaggcatct acagactcca atgcttcatc
    90061 taccattatt aaatctttct tagatagact cccaaaaaat cctgtatatg gataccttcc
    90121 tatattgact atatcttgta cagtcattaa atcacctaat aatctatttg taagtactaa
    90181 agccattttt tttgataatg cttttcttga tatacaattt atgtttacac cattcaaata
    90241 tatttcacct tttattggtg atataagttt agataaggac cttaataggg tagtttttcc
    90301 agctccatta cttcccaaaa gacatagtat ttctccattt tttacttcta catttatatt
    90361 acttataaca actttgttat tgtatcctac acttaaatta ttagttttca acatgtctaa
    90421 gccctatcct tccttttcac caataacatt actacaattg gagctcctaa taaagatgtt
    90481 atcgtactta ttggtaattc tactggtgat aaaattactc ttgatattaa atcacaaaga
    90541 gctgtaacta tactgcctaa aaatattact actggtatca aaactctatt atctgatgtt
    90601 ttaaatatca tttttgaaat ttgtggcact gcaagtccaa taaaccctat aggtcctgca
    90661 aatgctgata ctattgctgc taatatacta gatataaata ctatcaaaac tctaaaaaat
    90721 cttatattta tgccaatact ttttgcatac tcttctccta gtaaaaaagc atttaaaggt
    90781 tttattatga atacagtcat caaaagacct aatataccaa ctattataag tatttctacc
    90841 ttttcccatg taaatccaga aaaacttccc atagaccaca tagtaaattc ttttaattta
    90901 tcactatttg caaatgattg taacacattt gttataccac tacatacata tccggtcata
    90961 attcctatta ttaaaagagt tgttatattc tttaccttat ttgcaaataa aatgactata
    91021 gacattacaa ttaaagctcc tataaaagct gctacaaata tactcattga atttacactc
    91081 tcaaatccca atgtgtatcc tcccaaaatc atgagagcta ctgataaagt agaacctgaa
    91141 gatactccta atatatacgg ttcaactatt gggtttttaa aaaatatctg taataaaata
    91201 cctgatactg ctaggcatgc tccacctacc atggttgcaa gtactctagg gattcttata
    91261 ttgtatatta ttttataatg ttctgtatta tccatacctc ttaatacaac atctattact
    91321 tctttaaatt caatttttac agagccaaat gctacacaca ctaaaaaagt aagtatcata
    91381 cttataatta atactataaa tattgttgta ttccttattc tcattttatt gataaaatcc
    91441 atttgtatac tcctcttagc aaagctatat taactaaaat ctataaaacc tatctttttg
    91501 tgtcctctct gtactattta tcataattta tataatgttt gattttttca cctgtagtac
    91561 ctgggtggaa catctcaact aaatctacta ttaattcgtc cgtcttatct actgattgat
    91621 aataatctgg agcaaacacc cataggttcc cgttttttac aacatccaaa tcagccaata
    91681 caggtgcact agattttata gaatctaaat ttggtgcata atctgaactt gatgagtata
    91741 caaatatatc tgcatctttt gcaacttcat gcaattgttc aatacttact cgcccttcat
    91801 ttgaatctat tgaagcacat gcatttattc caccagccat ttttatcata ttatccacat
    91861 atgaatcttt aggagctata taagcacttc cttcatatac agatgcccat acaactttag
    91921 gtttagcttt gttttttatt tttttactta cttcttctac cttttgtaca gttttattta
    91981 gttcactagt agccatatct tctttatcat aaaatgcagc tattaaactt gtccactcca
    92041 ttcttccaaa tggattttgc tctttatact cattgtctac aacataatta agccctaatt
    92101 cttttaattt gtcaataaat tttgtatcag cctctgataa accactactc actatagtta
    92161 agtcaggatt taagtctact attttttcat aatctggtgc taaatttgaa ccaacgtaat
    92221 gtatttttcc atctttcatt aaatctttaa tttctttaat agtccagtac tgctcttctg
    92281 ttgttacggc ttttatacta tctagttcat ctattgttct cagagaacaa gcctgtgttg
    92341 tagatgctat taatacattg tccacaggcg ttctaactat attagcattt ttatattttt
    92401 caggaatttt aatcttcttt gggattaaaa tcagttctcg attatctcca tcagttactt
    92461 ttttaattcc atcttctaaa tcttcaacac taaatccact agcatatttt aattctaatt
    92521 tcttaccagt actagcttgt ttattctctt tgtcactttt actacaccct ataagacctc
    92581 ctaccataaa aattaccata gcaattaaaa aaaactgctt taaaacattt gatttaaatt
    92641 tcatctcttt cactccaata tcttattttt tatgagtggc taaaaaactt taataatata
    92701 tgctttttaa agtatactta ttaaagttat cctaaagtca tctttaataa gtataacctt
    92761 ttaataaaat aaaaaacttc tcctaattta ataaggagaa gttcatatat caactttaca
    92821 aaaacgaatt gatacttcat tttattataa attacaatct ccaccctaaa ttgaacttat
    92881 ataatactgg gcaggtctcc tgactcacgg cttttcctcc atcacccttc ccaaaatttt
    92941 tataaatttc agtggatttt gatttcgtat ccgtatacag tagcgggggc tgtagtgaat
    93001 tttcatcact ttccctatta aactaatata gtaccctagt attattttaa tttaattttt
    93061 attaagataa ttgtaattta ttgttgacct ctttgcaagg ttgatttaac atatatttaa
    93121 ttcattcatc aattttttaa tttcacatac ttgtttttca tttggtttta caaatggagc
    93181 agtcatataa tcacttattt gtaaccctct gatattcata gcttttttca ttgctggtat
    93241 aaatggattg gttattaagt aaaaatccat tgctttatta atatattttt gaatttctat
    93301 aaccttctcc atatctctat tattgtaagc ttcagcccat ttggagcaaa cttctggaat
    93361 taaatttgat aaccccccta tacaacctgc tcccccagac attagattat gtataaagtt
    93421 ttcatcataa ccactataaa ccttaaattc tgggaactct attttcatag tatttattaa
    93481 atctctggta tgtcccatca aagttactgt atccttatat ccaactatgt ttttatgttt
    93541 tcttgcaagt cttaatgtaa gttctggact taaatcataa ccagttctat ctggataatt
    93601 gtacaaatat atttcagcct ctgtattctt agctatttca ctataaaata actcaatact
    93661 atcatcatca agagagaaat aataagggct tattatcata acaccatctg ctccactatt
    93721 atgtgcatag tttgaaagtt ctatagattc atttatacac atacgacttg tacctataaa
    93781 cacttttact ctcttattta catgactagt tactaaatct ataagttctt tttgcatatc
    93841 catagacata ttaaagaact ctccagtact tcccattatg actagtccat ctacacctcc
    93901 atctataaga tggtcataca cttttttatt accttcttta tctaaatttc cttcttcatc
    93961 aaatattgta acaactggtg tcaaaaattc tgctttcata atttaaactc ctaaaattta
    94021 ttttaatatg ttcattaata catcagattt agctttaata ttaattatat taaaacagtt
    94081 acttaatgta attttttaaa attccaatac tctcaatctc acattcaact acatctccac
    94141 tactcatata tcgaggaggt gaaaatccca tccctactcc agaaggtgtt ccagtagcta
    94201 taatgtctcc agcctctaag gtcatacctt ttgaaagttc tgaaactatg tctgaaacgt
    94261 ctgatatgaa taatcctgta ttagaacttt gtctttcttc accatttacc ctactacata
    94321 ctttaagttt tataggaaaa ggaactgcac ttttatgtaa aatacatgga cctaaagagg
    94381 taaatgtatc taatcctttt cctctaaacc attgaacatg ttctttttgc aactttctag
    94441 cagaaatatc atttataaca gtgtaaccaa agatataatc ttctacctct tcttttctaa
    94501 tattaacacc tgttttacct attactactc caagttcaac ttcatagtct agttgattat
    94561 ttatctcaaa atgaccatct atctcatctt ctggacctat tgcctttgtc acacgttttg
    94621 taaaataaac cgttttttgt ggttcttcaa aactatcatc aaagtgagtt tgagtttctt
    94681 caagatggtc tttatagttc actcccacac ataagatatc atgtattggt ttttctatag
    94741 gaacatgtac cgtacatctc tctcttttaa aaacatcata attatagaat gtactttcat
    94801 ttataatagt tttcaactta ataatatctt cactagatac attttgaatt aattcattta
    94861 aatccttaaa atttctactg agatttaaag agttaacatc tataataaat aattcatctt
    94921 tagaaaaaac tccagttctt ttacattcat tttctccttc agtaaaactt acaaacttca
    94981 taatctcacc ctttattaaa attctatgta tttattttct tacttaaaga ttatacatag
    95041 ttgcatactc tagctattgc catttcagta tatccaaggg actctgcttt tgattgtttt
    95101 ccatttgcta catctacaac catatttaac aaatcatctg ttaattcttc cattgtttgt
    95161 ggaccataga taactggact agcatcaaaa tccatattat cttccatatt tgcaaaagtt
    95221 attttatttc cagttatttt tattactggt gctattggat ttcctgatgg tgttcctctt
    95281 cctgtactaa ataccactat ttgtgctcct cctgctacca taccagcaac agatgaagca
    95341 tcatttccag gggtatccat tataacaaga cctttcttat caatttgttt ggcataatca
    95401 tatacttcac ttatttgtct atgaccacct ttatgtatac aaccaagtga tttttcttct
    95461 aaacttgtta aaccaccagc tatatttcca ggagatggat taccttctct aacttcttct
    95521 ccaaccaatt ttaatgaatt ttcatatcta tgtactatat gtaatatttt ttcttttact
    95581 tcttcattta ctgctctcct agctagtata tgctctgcac ctataaattc agtagtttca
    95641 cttaaaattg atgttgctcc taaatcgaca agtttatcac ttaattcacc tattaatgga
    95701 tttgctgcta atccacttgt tgggtcagac ccaccacatt cagttcctag tataagttca
    95761 gatattggaa attcttcttt tctaagcaaa gaagcttctt gtgccatttc tctagcataa
    95821 cgaacagctt tttctatagt ttttaaagtt ccatgttctt cttgtattac aagagttttt
    95881 attggcttat ttgttctctc ttttattgca tcaactacca aatcattttg gcaattttcg
    95941 catcccaaag atacaactat tacaccatat acatttggat ttgctgcata accagccata
    96001 acatccatag ttaattgttg gtctgaatgt acttgtgaac atccattctg attattaaag
    96061 gtaactgccc cttgaacttg tgatgctatt attctagttg tatctgatgc acacacactc
    96121 gtaggcaata ttaatatgtg gtttcttata ccaactcttc catctggtct tttatatcca
    96181 taaaatttca tactgatttc ctcctaaaat agtctatata ctttctataa tttttatata
    96241 ttataatttt tattacactc actaatcaaa cagctaaaaa cctatttaaa aactatgtga
    96301 cactaaaagc aatgaataca acttttataa ctctataaat attattttat atattagtca
    96361 taacttgttt atccaaatcc tctctaacac ttctaacatt atgaatatgt acatgttggc
    96421 cactttttat ttcctgattt gcttctccta tatgttcacc atatttagta actttatcac
    96481 ctttggccat atcttttata gccaatttat gataaatagt tatatcatct agtgctgtaa
    96541 tcgtttttac tgttttgtct tttaatttaa aactaatttc actaccttta gctattgctt
    96601 caatagctac tgcaacatta tctttttcat caattatcac tgcatttatc attattcttg
    96661 ctctccttta taaataatat aattttatta atatcctaaa atctaattaa agaatttatt
    96721 attttaccaa caactcactg taatataaat taagctgtta ttgtaccatc ctcattttgt
    96781 tttgggaact taggacatcc atacttctta gcccaccaac tagttataag aggtactaat
    96841 attgcagtga caactactgc ggctgccact tgtgttgtag ctgttgcaac atatggttgc
    96901 catgatgggt caactaatgc aacagcagca ggtacagcaa ttgcatttcc agcagttgta
    96961 gctacagccc atcctgcata tcctggacgt tttcctataa atttatcaca gaatactata
    97021 aatatacctc ctacaaatac agatattaat ccaagtaata ctcctgataa acctcctttt
    97081 agtatacttg caagatttat gctactacca agtgcaaacc ctacaaaagg tacgagtaaa
    97141 ttacaccctg gctctaaaaa ctctttcatt tttttgtcaa aatttcctat tatcatacca
    97201 acaagtattg gcactattgc agccaataat gacaacaatg gtacatttgc aagacctgaa
    97261 gtcccaagag ctattaatgt aaaaaatggt ccatcattta aagtaagtaa actcatagtt
    97321 gcacaatctg tttcatctcc atatgaagtc atcaatgaaa gatatatact accattacta
    97381 tttgtaactg cacttataac agccaatgtt gtcagaccaa ggacaccatc cattccaaat
    97441 agctttccta taagtatacc tatcaaagca cctatagcaa atttagaacc aagaagtata
    97501 ccacctctct ttaaaacttt tggcatttct ctaaattgaa gctgagttcc caagcatacc
    97561 agttgaaccc caattatagt tgcagaccca acacttgaaa atactgctgt cgtaaacgaa
    97621 cctatttgta caatatctgg gcaaaaggta ttaatgaaag ctgctataaa cattggcact
    97681 atcatcatac ctgcaggaat ttttttaata aaatccatta tcataaagtt aatcctccta
    97741 aaacatgata tttaattact cttattaagt ttttagcttt aattctaacg gccgtttcgg
    97801 ttcgtattta agaactaagt ttttaattac gaatctttga attaatgata gcattttcct
    97861 atttatgagt caataaaaaa aataaatttt tgtcaaaatt ttttcaaact ttctgataat
    97921 accttgtata ttatcaaatg acttccttat atgcaaaaat acagcgtatt taaaattata
    97981 tagtattcaa aactataaag tttttataca gtgtaaaaaa tagataaaat ataagttcat
    98041 aatattttga tatttacata taaaaataac tattgcatat atttacttaa attatataac
    98101 taaatatcac ttactttctt taggtatatt ttggaaatta gttattcctt aatgtacagt
    98161 ctaaaaaaat atctatctgt atctaaatca agagcttatt tatatataaa tttacatatt
    98221 tattttctac attgtaaaat atcgtatagt gtgctaaaat caacatattc taatacttta
    98281 aattaataaa aagaggggga aatttatgac ttcagataat catcgcccaa cagctaggat
    98341 attagatatt ttagaagcat tagcagaatc cgaaaatgga tatactctta cagaaatagc
    98401 agatgttatc aatgctccaa aaagtagcat ctttcctata gttcatacac ttaatgctag
    98461 aaaatacatt actattgata aaaacacatc caaatattct atagggatac gttcttacac
    98521 attagggtct tcattttttg aaaaaagaac tatttttaac tatataattg acgaaatgac
    98581 taatatagtt aattcctgtt ctgaaacttg tcagcttggt atacttgaca ataatgaagt
    98641 tctttatatt ggaaaagtag attctccaga accgattaga cttatttctt atgttggaaa
    98701 aaaaatacct gctaattgta caggtcttgg aaaagctctt ttatgtgatt ttgacaagga
    98761 aaaactaata agcttatatc cagatggtct aaaaggtttt acagaaaaat caattacaga
    98821 ttttgatgtt ttatacgacc agcttcttga agttcaaaga acacaaatag cttcagagtg
    98881 tgaggaatca atggaacacc taaaatgtct tgccgtacca ataagaaaaa atggatgtat
    98941 aagagctgct gttagtgtaa cactgccttt atttagagct aatgacgaaa aaatagaact
    99001 gataaaaaaa ttactcttaa atgctcagaa aaatattcaa tcaatgatgg aagaacgtaa
    99061 tgaagacatt gtaataaatt agattaatat tctgtatatg gaagatatca aaacataata
    99121 attaaaaatt ttgttttaaa ctaatgtatt tatttgattt atactataaa aacaaagttg
    99181 ctgatttaac tacagtaact ttgttttttt tataatattt tttatatttt tattgacatg
    99241 ataaaaatac tatgttaaat tctaatcata atcgtaatta cgaattaagt tcttatataa
    99301 gaaccagcaa ccctatctca atctaagata cgatatatta tgagtaaatt agtgaaaatt
    99361 gttagatata tatttttaca taaaaatcaa tgaaaataaa aggagatttt agttatgagc
    99421 atttattatg taccaccaat aaatttactt gggaaaggat gtcttaatga agctaaagat
    99481 tcaattaaat cattaggaac taaaaaagca tttattgtta gtgataaatt tctagtttca
    99541 aatggtactg taaaaaaagt aacagatatt ttatctcaga tagatataga ctttgttgtt
    99601 tatgatgaag ttaaacaaaa tccaactgta actaatgtga ataaaggact taaaatatta
    99661 aaatcagaaa attgcgactt cgttataact ataggaggtg gttctccaca agactgtggt
    99721 aaagctatct ctatattagc cactaatgga ggagatatta gagactatga aggtatcaac
    99781 aaaacttcta aaaaatgtct tcctatcata gctataacta ctactgctgg tacatctgct
    99841 gaagttacaa taaactatgt tataactgat gaagacagac atgtaaagat gataatggtt
    99901 gataccaatt cactagccac aatgacagta aatgacccag aattaatgat tagcaaacca
    99961 tctaatttaa cagcagcaac tggtatggat gcactaactc atgctataga agctgtagta
   100021 gctaatggtg cttatgatgt tacagattca actgccttat atgctataaa gcagatattt
   100081 aaataccttc caagagctgt taaaaatggt aatgacatag aagctagaga acaaatgtgt
   100141 tatgcttgtt ttttaaatgg aattgccttt agtaatgcag gtcttggaaa tgtacatgct
   100201 atggctcatc aattaggagg tttatatgat ttacctcatg gagtatgtaa tgccatgcta
   100261 cttccaatag ttgaggagga aaatgctaaa tcagcccctg ccaaattccg accaatagct
   100321 gaagttattg gaatggatgt aaataataaa tcagataaag agtgtgttga ctttgtaata
   100381 gataagataa aagctctttc tgaagaggtt ggaatcccaa aatctttaaa agatgtaggt
   100441 gttgataatc ctaattttga attgcttgca gaaaactcta tgaaagatgc ttgtgctggt
   100501 gctaatcctg ttttctttga taaagataag attatagaat tgtttatgaa aatatcttaa
   100561 ttatgtatat ttataagaga gtgcctcaaa atatctttgt tttgttaata gcactctctt
   100621 attacacttt ttaaatagta ctctttatga gaagttaata tataatccta ttaatttaag
   100681 aatcattatc ccaataaaaa actcaaaatt tttcttaatg aattataact gttgttgtat
   100741 ctggtatatt atcatatatc cactttgcat tttccgtact taatcttata catccatgac
   100801 taagagcttc accaagtctg ccatctatta tataacttcc tgttgaatca tatagtacag
   100861 aatgatagta atatccacct ttaattctag tagcatactt aactgaatac tcatccgttc
   100921 caaaagaagg ttttcttcca cttatataaa atatacctgt tatagttgga gtctcaggct
   100981 tgcctatagt acattgccac ttgtaaagtt gtccccatcc tccattatct ttcttaaaaa
   101041 tataagtata tttatttcta aggtctgtta caattagata atcgctagta cttttaatat
   101101 tattttcgtt aacaaattta atcatgtcag tataaaaata cttataatct aattcatttg
   101161 gtttattccc atcaattgat aaaaaataat taaaaacata tcctatttta tcatcatata
   101221 caaccttact ccaatctcca tctacttgaa ggacttcaac cctagatttt tcaggaatta
   101281 ctgtaattat attggaagtt gtagatttat cttctcttaa gtttaagtta ctccaagcat
   101341 attcgcttac tgataccaac tccttataca catatccttc ttgagaattg tacatcacct
   101401 taatccagtc atcttcctca tccaatactt ccattttggc tccctgaggt attactgtta
   101461 tgatacttga attggtagat ttagcagacc tcaaatttat atttgctaaa gcatatttat
   101521 atataggtgc tctatatttt ttaatattta gtttagttaa tttcacacat atccatcctc
   101581 tcatatgtct ttttacaaca ttttatgaaa ttcgatatgt attcgttctc ctattttcaa
   101641 actttacttg tattactaag aatattgcta catatactta tatattctca cctatattta
   101701 tctatttatt taaatttatg atattacatt ctttaatata ctcttcaatt atacctctag
   101761 ccacattaaa ataacttata cacttgtcaa ctatgactgc atcactacta actactctat
   101821 ctaatttttc caatacaaca tctgcatttt ttactaattc tacttcagtt tcaattcccc
   101881 aagttttggc atgctctaat atcctatact ttaaatttcc tgaattagaa actggagcat
   101941 ctaaataaaa tttaagattc tgtgcattgt atttattaaa aaatttacct atcagattca
   102001 aagcttcttc tgttttatct ataatcttat aggttcccct aagacctgct aaatctctta
   102061 tattgccatc acttcctatt actagagtac caccagataa tcctacctct atggatatta
   102121 tcaaattaaa gccatctata tttacggtat cttctttgat tttatctaga gaaagcctct
   102181 ttgattgtct tataatattt ttttcatcag tacagactgc tctttttaat gcatctcttt
   102241 gtcttataga aaactgatat ctatcaccaa caaaagtaac gactgggtct attttgtaat
   102301 ccctatttaa taaccattct atttcttctt tagcctttat aagtcttgtt aattctttac
   102361 ttgaaaacca tcttttatca ctatcatcaa accctctttt agatatctta tttatatcat
   102421 ttcaccacct tgctttaaag atataactgt actacattaa atacagatta tttcaccttt
   102481 taagataatt tttaatacca ttatcttatc catttagatt attcaatatt tataattaat
   102541 tataacgctt aaccccactt aataatacag aataatagat tctatattat atttataact
   102601 ttataacata aataggtagt gtttctaaat aaacttttta gctcataaaa taatcttctt
   102661 ttataaaatc aaatatattt ttattattta aacagtaaaa aagagactta tctctatttt
   102721 ttgagatagt ctctttctaa aatctactta taatgataat tttaggttta tatattaaac
   102781 ttatgttata cttcttttat catattagga gatagaatat cattaagagc ttctgtcata
   102841 gttggatgtg cataaacacg gtctcttaaa tatgtatact ctacttctaa atctacagct
   102901 aattgaataa gatggataat ctcacttgaa ttttcacata tcatactagc tccaagtatc
   102961 ttattggatt ttttatctat cactattttt ataaacccat ctgccttgcc aatctgttta
   103021 gctcttggaa ttgcttctac tggcatcttt gccactaata cttcatatcc cttttcttta
   103081 gcttgcttaa cattaagacc aactcttgaa aatgctggac ttataaatat agaatttggg
   103141 atattctttc tatcattagt tgttctagtc ttatctccaa ataactgatt aataactatg
   103201 cgataatcat ccaatgaaat ataagtaaat tgtggacctc catttatatc tcctatagcc
   103261 catatatgct ctttattagt cttaagagtt tctgagactt taataaatcc tctttcattt
   103321 aattctatac ctgcattttc tagccctagc ccttcagtgt ttgcttttct tcctgtagct
   103381 acaagtatca tattacttgt taattcttta gatttaccat ctacttcata ttctactatt
   103441 gctaattcag aaacttcttt aatctctttt atatttgcat tattaacaat ttttacattt
   103501 ctctttgcaa gtaattttat tatttcttct gaatcctcaa catcttcatt tggtaaaatg
   103561 ccattattag agtttaatat tgtaacttct gctccaaatg aactataaat accagcaaat
   103621 tctaaaccta taaatccagc tcctataatt gtcatttttt taggtaaaac tcttagattc
   103681 ataagagact cactatcata tactatattc ttattttcaa ttcccttaat attaggtata
   103741 aatggtcttg aaccagtatt aataaatata ttatctgcta ctaactcata aatttcattt
   103801 tcagttttga cttgaactgt tttttcatca atgaaagttc ccattcctgt gaatatagtt
   103861 acattctcat ttgaatttaa tttattatag ttagcttctc tgagttttgt aattaaagtt
   103921 tcttttttat ctatagcttt ctcatattca gcttgtactt catcccaaga atttatattc
   103981 tttgttttta cgctgtttgc tgaattttct aagctttttg ttggtataca tgccacattt
   104041 acacatgttc caccatacat cttgtttgac ttttctatta aagctacttt taatcccctg
   104101 tttgccaaat cccctgctaa tgtttttcca ccttttccaa atcctattat tatagcatca
   104161 aatgtttttt tcatataaaa ttcaaccctt tcttgtattg tttatacttt tactataaca
   104221 agattattta ggtggtacaa ttaggcactt ttttgtaacc ttaaattgat ttataaactt
   104281 atacttaaat acttttattt atttctctga ttttcaataa atgatgccat agttgcctta
   104341 tccatagctc ctggaatata ctgagttaca tatccttcct tgtcaattat aaatgtagtt
   104401 ggaaaagcat taattccata ttgatatgct aatgctccat cttcatcaag tacaacaggg
   104461 aatgtataac cttggtcttt taagaagtta actacatgtt cccttgaacc ttctctacct
   104521 aaattaggtg aagctactcc taaaattact acatcatcat tatttttatt atagtcttta
   104581 tacagttgtt ctatataagg catttcttct ttacatggag gacaccatgt agcccagaaa
   104641 tttaagaata caactttgcc ttcataatca cttaatttat gtgttttacc atactggtct
   104701 gttaaagtaa aatcaataga ctttattcta tcttcatcat tagacccttt atcattattg
   104761 tcattattag agtctttttg actatcatta ccatcagaat tttcttcttt atcagtagaa
   104821 ttttctcgct tattttcttc ttgcttgctt tcaattttac tattttgtga cgtattaaag
   104881 tgtttgctta tacttccaaa tccatttacc atcattaata ttcctgatac tataagtata
   104941 atcccaccta tttttttaat aatttccatg ttagatttta tcttatctat agttttaaat
   105001 agtttactgt aaaacatagc tgtaattatg aatggcaaaa taaaaccaat agtatatact
   105061 gctattaaaa gattggcact aagatgatta cttgaacttg aaaccatgac taatacagat
   105121 gccaatattg gaccaataca aggtgtccat ccaaaactaa acgtaaaacc taatataaaa
   105181 gctgttattg ctttcatttc tttaaactta acattaaatc ttttttctct attcaatatt
   105241 gaagatttaa ttattcccat gtaaaataat cccatgataa taattataat cccaccaata
   105301 aacattatta aatctttatt ttcattaaaa aacatactca atacttttac tgatgaaccc
   105361 aatataaaga atgttgttga gattccaaga gcaaaaaata tagtattttt aaataaagaa
   105421 cttcctataa aactcgtctt tccttctttt aaattttcta cactactatt tgacaatata
   105481 ctcaaataaa taggcaaaat tggcagtata catggtgaaa agaatgatac tataccttct
   105541 ataaatacta aaaataaatt tacattttgc aaattaaaat tcctccttat tttatttcca
   105601 atattacaat cccatttcta aattaaaatc taactaaaaa attatgtaat tttaatacat
   105661 ttttctactc atagcttaat taaattttca ttacttacag agtaaatttt agtatttatc
   105721 acaatttaaa tttttattgc tccacataat cattttttcc atgacaggaa gcaatcgtaa
   105781 tcctgattca cttaaaaaat atgttgactc tacaacatta ttaaccaact ttttttggtt
   105841 gactataatc ccctgttcaa ttaaaaaatc tagttgttga actaacattt tcttactaca
   105901 gtctggtata gctctttgta gctctccaaa tcgtttttta tcttcttgta ttttccatat
   105961 aattatagcc acccattttt tacctaaaat atttgataaa gcttctactg gacaattata
   106021 tatcatatca tctatgttgt acattttatt ctcctctttt ctttatttaa tttattaaac
   106081 aaacttttat agcaatatat ttattaatat tataaatata cctag
//
LOCUS       DAFAZV010000011        93757 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFAZV010000011 DAFAZV010000000
VERSION     DAFAZV010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 93757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93757
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.011"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..403)
                     /locus_tag="KOU88_001198"
     CDS             complement(<1..403)
                     /locus_tag="KOU88_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211101.1"
                     /translation="MDGDILMSKILKYKNEMFLFILVVITYLIITKIFFSKTTIFYDL
                     NNTYDVLLDTDTGVLFNLNVFAISQDNSKHILFSAIISIFAYPIYLFCTSIANPGTTD
                     FNSAYGFGLICLQIITSAMSITLVFNHIKKIK"
     gene            complement(787..1929)
                     /locus_tag="KOU88_001199"
     CDS             complement(787..1929)
                     /locus_tag="KOU88_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK3211102.1"
                     /translation="MRYVEYGKTGKMVSVVGYGGLRFDLEKSNQENADLVKYAYEKGI
                     NYFDTAPGYCDDRSEDIFGLAFRQMIKEGKTDFYVSTKEKPKACDTSEKAIEAVKKSI
                     ERLGVSKINFYHVWNIRKMEHYELAMRPGGQYEGLLKCKEEGLIDHIVFSSHQPGDEV
                     IDILSENKFEGVTMGINILNFPYRLKGAKYAVDNGYGVVAMNPLSGGTIPKYNKELSF
                     LSKDGESTIESALRFNIGISQISISLIGFNKKQDIDDACKIADENRIYSDEDIHDIET
                     RLNKNMNEICTGCGYCKVCPKGINTPAYMLFYNEKQMFKKSDEEMTKLVYGLGHWNYT
                     MNSKAKAKECISCGKCEVECTQHLPIIDRLKEIKKWEEDGANSVKV"
     gene            complement(2070..2936)
                     /locus_tag="KOU88_001200"
     CDS             complement(2070..2936)
                     /locus_tag="KOU88_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBK3211103.1"
                     /translation="MDNYKKVKQVLWIILFANFAVALLKIIIGNQIKSYSMTADGFHS
                     LSDGASNIVGLIGIFFASKPKDKNHPYGHKKFEIITSLFISGMLFVIAIKIILSAVLR
                     IANPVVPAITIESLIALIITLFINIFVCMYEYRIGTKLNSYVLISDSLHTRSDIFVSL
                     GVLVTLVGVKLGFPVIIESIVPIIISAFIIYSAYGIFRPSIGILVDRVAVDEDYIKEI
                     VFEFNEVRDVHNIRSRGSKSSIYIDMHVMVDPFISVEQSHDLTHKIEKQIQEEINENA
                     QVIVHIEPFYSF"
     gene            complement(3270..4817)
                     /locus_tag="KOU88_001201"
     CDS             complement(3270..4817)
                     /locus_tag="KOU88_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK3211104.1"
                     /translation="MANFFNFILLQKDKIIELLIQHMSLTVTSILIAIIVGVPLGIII
                     SRISSLRKFVLGFVNLVQAVPSMALLGLLVPILGIGSKPAIFMVVVYSLLPIVKNTYI
                     GITSIDPVVLESAKGIGLTRNQTLFKIQFPLALPIIMGGVRISAVTAVGLMTLAAFIG
                     AGGLGYLVFSGVQTVNNNMILAGAIPSCIIALLVDYLFSKIEVAVTPKGLNPKAPKKN
                     YIALKVISVVLVVSMLFVVFSSSFSSKKDTITIGSKDYTEQLILGNVYAELVEKNTNL
                     KVKKNLNLGGSSVAFNAIKSGELDMYVDYTGTLLVNVMKHAPIKDADEAYNVVKDTME
                     KENQLTLLDPLGFNNTYTLAMMPETAEKYGINTISDLTKYGKEFTFSPTLEFENREDG
                     LVGLSRDYGLKFKDVKAMNGSLRYTALDNNESQVIDAFLTDGLIKKFNLKILEDDKNF
                     FVPYYAAPLVREDTLKKYPELEKVMNMLSGKINEETMRELNYQVDELGKSPEEVAHSF
                     LVKEGLV"
     gene            complement(4810..5946)
                     /locus_tag="KOU88_001202"
     CDS             complement(4810..5946)
                     /locus_tag="KOU88_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211105.1"
                     /translation="MIEIRNVTKKIGNNVILDDISLVVETGTLVVLIGSSGCGKTTTL
                     KLINKLIKPTSGEIYINGKPISQENEIELRRKIGYVIQNTGLFPHLTIKENIELIPRL
                     KKEKSVEEIEKRTLQLLEMVGLDSDEFLNKYPSELSGGQQQRIGVARAIATDAEIILM
                     DEPFSALDPITRTSLQEQLFSLQDELKKTIIFVTHDMDEALKIADKICIMKDGRIAQY
                     DTPENILRKPANDFVKDFIGEDRVWDNPEYIKARDIMIKNPIAVNSTRTVTQGIEIMR
                     TSKVDSLLIIDRAKTLKGIVTVKDMKDIDDKSILLADIMSSEPLHVNEGDNLVEILNV
                     MNRNSVGYIPVISDENKLVGLITRSSLLSVLSEQFLEMEVSVLG"
     gene            complement(6209..7306)
                     /gene="dinB"
                     /locus_tag="KOU88_001203"
     CDS             complement(6209..7306)
                     /gene="dinB"
                     /locus_tag="KOU88_001203"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBK3211106.1"
                     /translation="MKHYRKIIHIDMDAFYASIEQRDNKKLKGRPVIVGGNPQSRGVV
                     ATCSYEARKFGIHSAMPSAVAYNRCPYAVFVRPRFDVYKSVSEQIRDIFYRYTDLVEP
                     LSLDEAYLDVTKNKKNIDSSIEIAKQIKKDIFREVGLTSSAGVSYNKFLAKIASDLRK
                     PNGLTVITEENAQDFLDKLPVNKFFGVGKVTSNTLKNLGIKTGYDLRCLNLFELENIF
                     KKRGYELYKFARGIDDRPVEPNRVRKSVGAETTLSHNLDIDEEETRNILDELCEEVCH
                     RLKNSEKFGKTLTLKIKYEDFTKITRSLSLEHYIDEYNDIRSGVDNLLRNVEVNGKQI
                     RLLGVTISNLSDKKETYKDITLFEYMDSIQM"
     gene            complement(7696..9201)
                     /locus_tag="KOU88_001204"
     CDS             complement(7696..9201)
                     /locus_tag="KOU88_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003374392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBK3211107.1"
                     /translation="MKVGFDHKKYLEEQSKYILERVNNFDKLYLEFGGKLMGDLHAKR
                     VLPGFDENAKIKVLQHMKEKVEVVICVYAGDIERNKIRGDFGITYDMEVLRLIDDLRG
                     YELDVNSVVITRFEGQPATTVFINKLERRGIKVYKHYPTKGYPSDVETIVSDEGYGAN
                     EYIETTKPIVVVTAPGPNSGKLGTCLSQLYHENKRGNVVGYSKFETFPVWNVPVKHPL
                     NIAYEAATVDLKDVNMIDSFHLETYGEMSVNYNRDLELFPVLKKIIEKITGKESIFQS
                     PTDMGVNRVGFGIIDDEVIRKASIEEIIRRYFKTACEYKKGQVDKGAYDRMKMIMEEL
                     NLKPEDRNVVLPARNYSNKLKESADKNDTCPVVALELEDGTILTGKGSDLMNGTAAVV
                     LNAIKHLANISDDMHLISPVILEPIINLKTKTLASRNVSLSCQEVLTALSICAVTNPT
                     AQFAMEKLALLKGCQAHSTTILNRDDEQTFRKLGIDVTCDPEYPSQNLYYS"
     gene            complement(9462..9812)
                     /locus_tag="KOU88_001205"
     CDS             complement(9462..9812)
                     /locus_tag="KOU88_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211108.1"
                     /translation="MAIVDKIFNEIKLMVARLLLGKKYSEYEEKDLVYNTEEEVILIT
                     LKRLVFQGNVNEAEEILFDKAKSVNSENMQYIAIEFYTMLMEKTDEELEAMNFSKQEV
                     YQGIEDIRKVLNLE"
     gene            complement(10035..10226)
                     /locus_tag="KOU88_001206"
     CDS             complement(10035..10226)
                     /locus_tag="KOU88_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211109.1"
                     /translation="MLDRFFGEGGFGGCAWWIIILFFLFLAFQDCWAEMDLCAWIPFL
                     ILLLILCECGDVFDGGCGC"
     gene            complement(10344..11270)
                     /locus_tag="KOU88_001207"
     CDS             complement(10344..11270)
                     /locus_tag="KOU88_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3211110.1"
                     /translation="MRKIVLKDILFLVTTLSIIVILLLVTNITTNSKIKSTSESYLKS
                     DKNSVRQNGIQRSTKSSTKNTAFKTTILNTGKSDCILVEIGNKVIMIDTGEDKNGKQI
                     VDRLKEKGINTLDYLILTHLDKDHIGGVDSVLSSVKVKNIIQANYKKDSKQYDEYIDS
                     LKKADIEPVLLKDNMNIVINGAEINIHPASKSKYESSNDYSIITNISYGAHKFLFAGD
                     AEEERLSEFINGNTLKYDFVKMPHHGRYDKLTETFLESISPQYAVITCSEKKEPEEGV
                     LKILERLNIKTFLTSNGEVVINSDGKTLSVNQ"
     gene            complement(11404..12900)
                     /locus_tag="KOU88_001208"
     CDS             complement(11404..12900)
                     /locus_tag="KOU88_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBK3211111.1"
                     /translation="MFEFETQLKRLKHEVLTAVARLSIEENLTKENIEKIPYEIIKGE
                     KARYRCCVYKEREVVLERAQLALSLTPNSKYGDINPDSVSLDTDEQIIYIVEAACDRC
                     PINEFTVTELCRGCLAHRCKEACKFGAISYINGRAYINHDLCKACGMCKSSCQYDAIS
                     EVVRPCKSVCPTGALDFNRNTMKAMIHEDNCINCGACMSACPFGAISDKSLIAPVAKK
                     LAKKENMYAIVAPAITGQIDSNITYGQLKNAIKSLGFVDMIEASCGADAVTVHESNEL
                     IERIKSGDNYMTNSCCPGFFKYIEKMFPDEKDRISSTVSPMVATGRLVKKIDSDAKVV
                     FIGPCTAKKSEATEKSLKDSVDYVLTFEELMALFEAFNIDLSKCSNEDINDGSIFGRG
                     FGASGGLAKSVQNYIAEKGLSFDFEPIKVSGPRQIKKTMTMAKLGRLEGNFIEGMMCE
                     EGCINGAGKFLSGVKAKNTFDRKNGQSTKKSVLSNDKIKEFEDVNLER"
     gene            complement(13180..14670)
                     /locus_tag="KOU88_001209"
     CDS             complement(13180..14670)
                     /locus_tag="KOU88_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBK3211112.1"
                     /translation="MFQFETQIHKLRHDVLTAIARLGKEDNLTREAMDNIQYEIIKGE
                     KPTYRCCVYKERAIISERVNVSMGLQPGQDKIDLDTMDIEEDEQIIYILEAACDSCPI
                     NEFTVTDICRGCLAHRCKEACKFGAITHVGGMAYINHELCKACGMCKKACQYDAISEV
                     VRPCKSVCPTNALGFDRENMKAMIHEDKCLNCGACMSACPFGAISDKSLIAPVARKLV
                     QKEKMYAVVAPAITGQVEANVTYGQIKNAIKSLGFVDVLEAACGADAVTVHESLEFAE
                     RMEKGEAFMTNSCCPGFVGYIEKTYPNHVGKISSTVSPMIASGRFIKSHEPDAKVVFI
                     GPCTAKKSEAAKKELKGAVDYVLTFEEIMALFEAFDIDLAKCSNEDIDDASIFGRGFG
                     AAGGLTKAIENYLAEKGIGVNFEPVKISGSREIKKTMTMANLGKLEGNFIEGMMCEGG
                     CINGSGKFLSGAKVKATFDRKNSQSTKKSVLANTKIKDFSNINLEK"
     gene            15137..15337
                     /locus_tag="KOU88_001210"
     CDS             15137..15337
                     /locus_tag="KOU88_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK3211113.1"
                     /translation="MKNGIVKWFNNEKGFGFISVEGEDDVFVHFSAIQNDGYKTLEEG
                     EKVSFDITQGNRGPQAENVNRI"
     gene            complement(15517..16395)
                     /gene="speB"
                     /locus_tag="KOU88_001211"
     CDS             complement(15517..16395)
                     /gene="speB"
                     /locus_tag="KOU88_001211"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBK3211114.1"
                     /translation="MKNNFYHMNTFMSMDKNYEESNLIVFGVGFDGTTSNRPGARFAS
                     SSMRKEFYGLETYSPFLDLDLEDYNICDYGDLEISVGSTEQVLKEIYQETYKIVRDSK
                     VPFMIGGEHLVTLPAFKAVHEKYNDIYVIHFDAHTDLREEYNNSKNSHATVIKRIWDI
                     VGDNKIFQFGIRSGTKEEFKFATEEKHTYMEIGGIDTFENIVNMLNGKNIYLTIDLDV
                     LDASVFPGTGTPEPGGVNYREFQEIFKIIKNSNINIVGCDIVELSPDYDTTGVSTVIA
                     CKILRELCLIISDKIK"
     gene            complement(16385..17236)
                     /gene="speE"
                     /locus_tag="KOU88_001212"
     CDS             complement(16385..17236)
                     /gene="speE"
                     /locus_tag="KOU88_001212"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBK3211115.1"
                     /translation="MELWYTEEWTENVRFSIKVNKHLFEGKSQFQRIDVFDSDEFGKF
                     LTIDGLMMVTYKDEFIYHEMITHVPMATNLNIKKVLVIGGGDGGTVRELSRYPQIEKI
                     DMVEIDKMVVDVSKEYMDICSCKLDDKRVSLYFEDGVNFVKCAHDKSYDLIIVDSTDP
                     IGPGEGLFSTDFYKDCYRILTDDGILVNQSESPYFDFNAKEMKRANKKLKQIFPISEV
                     YQAHIPTYPSGHWLFGFASKKLNPVKNQDRNGWEKLSLKTKYYNSDIHLGSFMLPQYV
                     KEMLDEE"
     gene            complement(17266..17679)
                     /gene="speD"
                     /locus_tag="KOU88_001213"
     CDS             complement(17266..17679)
                     /gene="speD"
                     /locus_tag="KOU88_001213"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBK3211116.1"
                     /translation="MKFETLGRHILVEYYNCDENVLKDPRLIENFMNDSALNAKATIV
                     DSVFHHFNPWGVSGAVIIAESHLTIHTWPEYGYAAADFFTCGDIDPWKSFELLEQLLK
                     SERSESTEIPRGLTTKIKKYSKKDLGKITHKPEAV"
     gene            complement(17766..19241)
                     /locus_tag="KOU88_001214"
     CDS             complement(17766..19241)
                     /locus_tag="KOU88_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBK3211117.1"
                     /translation="MDSEFANAVELSYECAPLLESLKEYSEKDIACFDVPGHVKNRGV
                     AILNKYLGESLMKMDINSSPTMDNVSAPNGIIKNAQDLLAQAYMADEAFFITNGTTQA
                     IHAMILSVIKPGEKVLLPRNIHKSVINALILCGGIPIFIQPEFDEKLGISLNITLEKV
                     RTEIEKDCNIKALFFLNPTYYGVCADLESIIELCHKNNVLVLVDEAHGAHFPFHLDLP
                     PSAISFGADMVAVSIHKTGGALTQSSALLLNRDNVSFEKVLQSINMLQSTSASYLLMA
                     SIDGARVNLVENGEKQLSKALNLSRYAKSKLNKIDGIKVLSTEILKQKGVKFIDETKL
                     CINVKELNLTGFEVYDLLYKNFSIQVELGDSYNILALVSIGTNKSDIDRLVKALSIIA
                     KIYRKESTLNEFNMVQINPIIKLNPREAFYAPKESVEINSCIDRICGESIMAYPPGIP
                     IIAPGELITEEIMEYIIFLKNSNAYLTDVQDKNLDRILVIK"
     gene            complement(19879..20532)
                     /locus_tag="KOU88_001215"
     CDS             complement(19879..20532)
                     /locus_tag="KOU88_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3211118.1"
                     /translation="MKVDPLTTQVYDYISKKIQNGEYEANQRITESEICKSIGVSRTP
                     AREALTRLAGENLLEKIPNKGFVVKEFQEKEKLDTYSVIGVLDALAGSSALQNLTESD
                     LVKMEELTEMMAVSIKYKNYNSYLKLSNEFHDIYITKSDNQVLVNLLNSLRYNFMSKS
                     YTSDNEDELYKMLTYSNNQHIEVVKSMRENDLENVERVLREHWKTIPIAEMKKEKLL"
     gene            complement(20777..22642)
                     /locus_tag="KOU88_001216"
     CDS             complement(20777..22642)
                     /locus_tag="KOU88_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 13 protein"
                     /protein_id="HBK3211119.1"
                     /translation="MQSVIEYNSWDKNFKAPFGALKFDEELTICVKVNEGYNIKSISL
                     EINREEEMRTITLNEELDNDKLGKCFCGKIEKFDGTGVYFYYFKVDVEMDGQIKTLFY
                     GKNRDNGYSCEYNYSDINKYQITVYKDFKVPTWYKEGILYHIFVDRFNNGNRSGKVDN
                     PKKNSFIYGNWEDTPMYIKDSQGDVIRWDFHGGNLRGIINKLGYLKKLGVSILYLSPI
                     FEASSNHKYDTGDYKKIDPMFGDEDTFKELIDKAKEKGISIVLDGVFSHTGADSKYFN
                     MYGNYNSLGAYQSKESPYYSWYMFEEFPQKYKSWWDVKTLPNINELEHSYMDYIIYDN
                     DSVINKWVNMGIKGWRLDVADELPTKFIRELKKELKNADDDSILIGEVWEDASNKISY
                     GQRRSYLLGEELDSVMGYPFRNNMFSFLKGEINSYELCNRYMQIKENYPKESFRSNLN
                     LIGTHDVTRAKTELNDDVDLVKLAVAIQMTFEGVPYIYYGDEAGLCGGVDPDNRRTYP
                     WKNEDEDMLNFYRDVIKIRNKNKLLSSGNTEFIYTNNDSVFSFIRVNENNDRMLILVN
                     RSENVESISLCIESSFIEEIPIKYSLKNANSTIQIENNELKVDLDSKSFRIFRVN"
     gene            complement(22647..25067)
                     /locus_tag="KOU88_001217"
     CDS             complement(22647..25067)
                     /locus_tag="KOU88_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan phosphorylase"
                     /protein_id="HBK3211120.1"
                     /translation="MVTISKKKFKQKFEVKMYSLYAQSIKEATDEQLLNVLCSLLKDE
                     IAKKWVATKLDKKKEVYYFSLEFLIGRQLKSNLLNLNIEEEVREGLSELGINLDDLIE
                     AEVDPALGNGGLGRLAACFLDSMASLNISGQGYGIRYKYGLFEQKFVNGYQVEVPDNW
                     LTEGRYAWETVRPNEATMVKFGGEVELIKEGSHLKVIHKNYLPVMAMPYDIPIIGYQN
                     QCINTLRLFKSEIPKRDFGELTSNALNYSGSYEEALKHKYYTEEISQVLYPDDSNYAG
                     KLLRLKQEYFFVSAGIQDIIRKYKKNKLNINNLFDKVAIHINDTHPTLCIPELMRILL
                     DEENLSWDEAWEITKKTVSYTNHTIMSEAMEKWPVSMMKELLPRIYMIIEEINRRYVE
                     ELNNKGYDQDRIKRMSIIDCDNINMANLCIVTSHSVNGVAKLHTHILETEVLKDFYQD
                     EPNKFNNKTNGIAHRRWLISSNPQLSNLITDLIGDSWKKDTLQLKNIEKFKNDSSVLQ
                     RLDDIKYNNKANLAKFIKDKYDLNVDPSSIFDVQVKRLHAYKRQLLNIFNVLHMYHEL
                     LDNPNLNLDPRTFIFGAKAAPGYYLAKCIIKFINSVASTINNDVRVKDKLKVVFLENY
                     GVSLAEIIIPAANVSEQISTTTKEASGTSNMKFMMNGAITLATLDGANVEICEQVGKE
                     NMFLFGLSAEQVLNYNKYGGYSSLDLYHSNMDIKRVVDDLINGFIPNLGEEGRSIYNS
                     LTTYNDEYFVLRDFENYGQAQADINRLYRDKEKWNKMSLVNIANSGFFSSDRTISEYA
                     KDIWFKRV"
     gene            complement(25081..26523)
                     /gene="glgA"
                     /locus_tag="KOU88_001218"
     CDS             complement(25081..26523)
                     /gene="glgA"
                     /locus_tag="KOU88_001218"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011053260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBK3211121.1"
                     /translation="MKVFYVTAECWPFAKTGGLGDVSYALPKELKKEGVDVRVIMPKY
                     STIPSYLKDQLKEIAVFSVRVGWRNQYCGLLEMELDGVKFYFIDNEFYFRREDERKSI
                     YGYGDDAERYTFFTDAVLEAISRIDFYPDVIHINDWHTGMLPLILKERYATLEGYKNI
                     KTMYTIHNLQYQGVFDKHVLYDILDLPQKYFDNGDIEYYGSINFMKAGINFADKIITV
                     SPTYANEIQTSFYGEQLDGLLRKESGKLKGILNGIDYDLNDPAKDKDIFVHYDVDSIN
                     KKVENKLRLQDILGLKKDSSIPLIGIVSRLVSQKGFDLIAYMMPELMREDLQIVVLGT
                     GEHQYQSMFNYYDSNFSDKVSARITFNASLAQQIYAASDMFLMPSLFEPCGIGQMLAM
                     RYGSLPIVRETGGLRDTVTPYNKFTGEGNGFSFKNYNAHEMFFCLKNAIKVFKDKEKW
                     IKLVENAMKTDNSWKKSAKEYIETYRDICD"
     gene            complement(26552..27682)
                     /gene="glgD"
                     /locus_tag="KOU88_001219"
     CDS             complement(26552..27682)
                     /gene="glgD"
                     /locus_tag="KOU88_001219"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HBK3211122.1"
                     /translation="MRNECLGIINLNKKGDPAINKLNYGRPIASTPIAGRYRIIDFAL
                     SNMINSGITKVGIFAKEKYRSLTDHIGSGKDWDLSRKKGGLSIFSPENTKYRNTYSHR
                     EGDIYTILANLDYIEKSEEEYILIAPSYMLCNLNYSQALEYHKKSHNDITIIYKNVNN
                     ANKDFAGNLTLNLDSNNRVINVGNNLGKFPRANICMETYIMKREDFVECIYNIVNKGN
                     YCYLEEFIIEEAENMKIGAYEYTGYLKCVNSVESYFEMSKDLLNLEVADELLYSERKI
                     FTKEKNESPTIYTDSAKVENSFIASGCLIEGTVKDSIIFRKVNVEKGTVIENSIVMQN
                     CVIKSNAKLYNAILDKNTSVSNGKELRGDEKYPLVVEKNTNI"
     gene            complement(27684..28844)
                     /locus_tag="KOU88_001220"
     CDS             complement(27684..28844)
                     /locus_tag="KOU88_001220"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBK3211123.1"
                     /translation="MKKEMLAMILAGGQGSRLGVFTKRIAKPAVSFGGKYRIIDFVLS
                     NCSNSGIDTVGVLTQYRPLILNSHIGMGSHWDLDRINGGVYVLQPFMNEKEGNWYNGT
                     AHAIYQNMDFVDTYNPEYVLILSGDHIYKMDYSKMLKFHKEKGSKATIAVIEVPWDEA
                     SRFGIMNTNEDSSIYEFEEKPSEPKSNLASMGVYIFDWKMLRNYFKEAEKNPEINYDD
                     FGKNLIPKMLEDNVGMYAYPFKGYWRDVGTIQSLWDANMDIIKSPETLDLADPKWKIY
                     TNTMAMPPQYIGKNANVHRSMIADGCRILGEVGNSVLSHGVVVGKGSKVIDSVIMPNV
                     VIGENVTIEKAMIGECATINDNVQIKNVNNEINVVSEYENIEPRCVLIEGGL"
     gene            complement(29615..30658)
                     /locus_tag="KOU88_001221"
     CDS             complement(29615..30658)
                     /locus_tag="KOU88_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBK3211124.1"
                     /translation="MGTKIVLSIVLIVVVVAISLTCIRVIKQSKVGIIMRLGKFQKVA
                     ETGVHFLIPFLDKMAYVIDLREIVIDFPPQPVITKDNVTMQIDTVVYYKVTDPVRYVF
                     EIANPIAAIENLTATTLRNIIGELDLDETLTSRDIINVKMRTILDEATDKWGIKVNRV
                     ELKNIMPPQDIQVAMEKQMRAERERREAILQAEGNKSAAILQAEGEKQSAILTAEAKK
                     EAMVRVAEGEKESAILVAEGEAEAIRQTAIAKAQGEAEMIKRTQMATAEGLKLVFSAM
                     KEADIDNNILALKSMEALEKMAEGKSTKLVLPSEAVNFLGTFKGIKEVMSDDNKEVLD
                     IKEVLNDNESLKK"
     gene            complement(30679..31125)
                     /locus_tag="KOU88_001222"
     CDS             complement(30679..31125)
                     /locus_tag="KOU88_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBK3211125.1"
                     /translation="MKLIWLIVAVLFGIAEMLTPSLTLIWFSVGAVILIFLSSFIESI
                     FLQILIFAVISIAMLVVATKKIVKKDKGYKSNTNLQAMMSKKGIVTEEISPNNTGLVV
                     VEHETWTAISIDGEKIEKGSTVEVLKIEGVKLVVKKVDATVNVTNQ"
     gene            complement(31299..32879)
                     /locus_tag="KOU88_001223"
     CDS             complement(31299..32879)
                     /locus_tag="KOU88_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBK3211126.1"
                     /translation="MLIGTSKLSRNVDTACVEEVGIPMIVLMENAVISAMKNMDIDMY
                     NSYTVVCGVGNNGGDGLGIARHLNTYGKEVNVFLVGNLEKLSECSKINYNVLLNMGIN
                     IININKNDLSEKNYGDENEVDKIIKVEKQNIIKNKNLTIFKDRLSKSDVVVDAIFGTG
                     LKRDITGIFKEVIDIVNDNSKNTYSIDIPSGIDSDNGNVLGTCIRANKTISFEFYKRG
                     FLNYDTSTLIGDVVVEKIGVPDFITRKYHDEEFITDKTFVKNNIRRRDKHGFKSDFGK
                     VSIVAGSKGFYGASFIATESAVKSGSGLVTLISSEDVQEKVSIRLTEAMTLNFEEERL
                     NKLLNSSDAIGFGPGMGDNSQTFDKLLKIVENSNCPIVLDADGLNVMKDRCYKFLEWK
                     NRFVITPHLGEMARLTGDSIGYIREHRVDVAKEFAQKYNLVVLLKGYQTVITDGKKTY
                     INPTGNSCMATGGMGDCLLGMITSFIGQGMDILEATVSGAYIHGYIGDKLSKAMYTVN
                     ATDLISNISLTMKELLDI"
     gene            33678..34580
                     /locus_tag="KOU88_001224"
     CDS             33678..34580
                     /locus_tag="KOU88_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211127.1"
                     /translation="MSGIISVMTQSLILSIMALGVYITYKILDFPDMSADGSYTMGAS
                     IVAFSLTNGISPVVATLMAILCGCTAGLVTGILHIKFKISNLLSGILVMGMLYSINLR
                     IMGKSNIPLFSFKHLFNGEISPIVLALAFVFICKVLLDLFLKTGLGYTLKGVGDNSQM
                     IKSLGINIGSIKILGLMISNGLIALSGSLMAQFLGFSDVNMGIGTLVLGIASIIIGIT
                     LFKKFTFIKDTTAIIVGSFIYQFTIYFAMSLGMLSTDLKLITAIVIIAFLATGNLNIS
                     LKKNKCKASTKNKSEKRGVVDVTN"
     gene            34567..35322
                     /locus_tag="KOU88_001225"
     CDS             34567..35322
                     /locus_tag="KOU88_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3211128.1"
                     /translation="MLQIKNLSKSFPNPYGEPNTIFENLSIDIEDGEFVSIIGSNGTG
                     KSTLLNIISGLIKESSGQVLLNKHNLSNLAEHRRTQIVSRVFQDPSLGTCPSMTVREN
                     LSLALNKGKLLNLRKCLRYKRDFLENLLEGVSLDLKKYLDVQVKFLSGGQRQSLSLIM
                     SCLTNPSVLLLDEHTAALDPKTSNEVIELTNKIVREKNITTLMVTHNLKHALHYGDRL
                     IMLHKGEVVLDVKGKEKEQLTVEEILEKFEYAV"
     gene            35453..36475
                     /locus_tag="KOU88_001226"
     CDS             35453..36475
                     /locus_tag="KOU88_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3211129.1"
                     /translation="MINKKRLASLILAGALSISMLTGCSQGGDSGNSKQESNSKGKEV
                     KKIGITQLVEHPALDATRTGFVKALEKNGFKDGENIDIDFQNAQNDMPTTQSIASKFA
                     SDKKDLIFAISTPSAQAAFNATKDIPILITAVSDPVAAGLVKTLEKPGTNVSGTSDFV
                     SVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKNGFKVVEKGITTSNE
                     VNQGISSLVGKIDVLYVPTDNLVASSMPIVSKIATENKIPVIAAESGPVEKGALACQG
                     INYEKLGYKTGEMAVKILNGESVSDMPVATSDDTDIIVNEDILKALGMEKPSNENISY
                     VKTKQE"
     gene            complement(36639..37196)
                     /locus_tag="KOU88_001227"
     CDS             complement(36639..37196)
                     /locus_tag="KOU88_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBK3211130.1"
                     /translation="MTEKEKMLSGKGYYANDELLVKEREYCKKLTRLFNNTLEDEYEK
                     REDILRQLFGSVGKQINVEQNIRCDYGYNIHVGENFFANYDCIFLDVCKIEIGDNVML
                     APNVQIYTAYHPIDAQLRNSGIEYGSPVKIGDNVWIGGGVIITPGITIGDNVVIGAGS
                     VVTKDIPPNTVAVGNPCRVIKKIEE"
     gene            complement(37202..38278)
                     /locus_tag="KOU88_001228"
     CDS             complement(37202..38278)
                     /locus_tag="KOU88_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HBK3211131.1"
                     /translation="MSLYVDIEKDLSSFKLKVEIKQEKGTLGFLGESGSGKSMTLKCI
                     AGLEKPTRGKIVLNDRVLFDSEKKINLSTQDRKVGFLFQNYALFPHMTVSQNIELGLL
                     KLSKSEKKEIVARYLDILKLNGFEGRYPWQLSGGQQQRVALARALATSPDILLLDEPF
                     SALDHHLRSNMEKELMNMLKDYKGDILFVTHDIEEAYRVCDDIIVYNKGEGLPKRPKK
                     ELFESPKYLIEAKITGCKNISKLNRLDKNTIYATDWGCELTLNREIGDNIEYVGIREH
                     HIKVLDSNEDLNEKLCFELINIVENPFTYTIYVRKTDLSNECVPIQIELEKSKMRFKK
                     GDRIYLDFPQEYLFCFRYNYNKKE"
     gene            complement(38279..38962)
                     /gene="modB"
                     /locus_tag="KOU88_001229"
     CDS             complement(38279..38962)
                     /gene="modB"
                     /locus_tag="KOU88_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBK3211132.1"
                     /translation="MGTDWSPLWISLKTSILSTIITFVIGIFVSYIMANYRGKWKGLI
                     DGLFTLPLILPPTVVGFFLLLLCGKNGFIGKFLLNFDRTLIFSWTATVISAVVVSFPM
                     MYRTSRSAFEQIDNNMLSAARTLGLNEWKVFFKIAVPLAWPGIIGGLVLSFARALGEF
                     GATLMIAGNIPGKTQTMPIAIFFAVEGGDMNKAMMWVMIIVAISIAMILLLNYWSEFQ
                     QKIIGKRCG"
     gene            complement(39111..39923)
                     /gene="modA"
                     /locus_tag="KOU88_001230"
     CDS             complement(39111..39923)
                     /gene="modA"
                     /locus_tag="KOU88_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3211133.1"
                     /translation="MKKILGILGLVACLTLGTVGCNSNEDKKDNGKQEKTTKSSDSVE
                     LNISAAASLKEAMAKIEEEYKKVDSNVKLTVNYGASGSLQQQIEQGAPCDLFISAGQK
                     QMKALDEEKLLVSDTMKDLVKNDLVLISSADSSVSGMKDLTTDKVKKIAVGEAESVPA
                     GKYADEVLTNLNLKDKLKDKLVFAKDVKEVLAWVQSGNADVGFVYFSDTVNNDKIKVV
                     EKTDEKTHSPITYPVSVIKASKNVDAAKKFEEFLLSESGQKIFEEFGYKKVE"
     gene            40116..41045
                     /locus_tag="KOU88_001231"
     CDS             40116..41045
                     /locus_tag="KOU88_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211134.1"
                     /translation="MDSLSSLTPVEVAELLKITKNTVYELIKRGELPSYKVGKKIRVD
                     TKDVEEYINSQKTGKVKDTHFNNKNIDINNNFKIIISGQDVILDILARSVEKKLDGIS
                     TFRSYIGSYNALYELYNGRVSIASSHLWDFETDEYNSTFVKKLLPGIPCVLINLAYRM
                     QGFYVAKGNPKEITTWEDLTKPSITIVNREKGSGTRVLLDGKLRLLNFNGKHIKGYDN
                     EELSHLGVASTVSRGIADVGLGNEKAALQVNNIDFIPLHKERYDLVIKKEDLQNPVYQ
                     TIINIINSPEFKAELQGLGGYDLTDTGKTIAKV"
     gene            complement(41206..41655)
                     /locus_tag="KOU88_001232"
     CDS             complement(41206..41655)
                     /locus_tag="KOU88_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211135.1"
                     /translation="MKNKNNKDKNMLNIKVLRVLGVLLILFDYTGDTLNFYNFFAKPL
                     VSGNLYKTTGTDCIVFLLFIVECVYLVGRYILKVKINWSEIIENEKGNFINNLLVEKI
                     QEESNIVYNLLNSYVLPHIYKKARGLMFKTYHMLIYIKEKYYYVNIY"
     gene            complement(41858..42838)
                     /locus_tag="KOU88_001233"
     CDS             complement(41858..42838)
                     /locus_tag="KOU88_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3211136.1"
                     /translation="MKNSFKNCISLRNKFIIISIVFLLILLIVSYIFGKLVYNSSVGL
                     EQLIKNEDIVKIFSERKDKPLEKLKNYKTSELMIQSSNNYKLESLFITSNIKTRDTMI
                     LVHGIGSSYYEMLKVAYRYLDKGYNVLVYNQRNTGNSGGDNYTFGLYERYDLDSLVKF
                     VKNKFPEGRLGVHGFSMGAGTAAMHSEINSKDDKVDFYILDSPYSEMKDAIRMGVLEK
                     RIPDILINYVVTCGDLYNKFKSGFWYSDVKPYESVEKSNVPILFIHGTKDTVCNYQNS
                     KKMYDLVKHDKKDLWLIEGIGHVDGFEHDSTVYFNKIFKFIDSNVLSDKS"
     gene            complement(43043..43903)
                     /locus_tag="KOU88_001234"
     CDS             complement(43043..43903)
                     /locus_tag="KOU88_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HBK3211137.1"
                     /translation="MAMKWRDYADDVNLFEDFDKTIKPLTDEQRRKNINTLIAYFSKE
                     VPSKIYNLSNDEIKPRDILRGLLNVYPPKEIAPEILNMLHNLLLIECEERELVDVNDI
                     EEVEEGIAIWRGNITNLRADAIVNAANNKLLGCLQPLHLCVDNEIHSCAGPRLREDCD
                     KIIKKQGHLEYTGDAKITRGYCLPAKFVVHTVGPIVSGGQPSKEQEKQLLHCYKSCLN
                     TIKEIDEIKNIVFCGISTGVFGYPKKEAANLAVSRVRLWLKENPEKNLKVVFNVFTEE
                     EEEKYRRIFK"
     gene            complement(44220..45548)
                     /locus_tag="KOU88_001235"
     CDS             complement(44220..45548)
                     /locus_tag="KOU88_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBK3211138.1"
                     /translation="MEKFSVVIAGGGSTYTPEIILMLLDNLDRLPLRAIKLYDNDEER
                     QNKVAKACEILIKEKDPNIEYLATTCPKEAYTDVDFCLAHIRVGKLEMRELDEKIPLK
                     HGVVGQETCGPGGIAYGMRSIEGVLENIDYMEKYSPNCWMLNYSNPASIIAEAVRRLR
                     PNSRVINICDMPIGMEHNIARIAGLKSRKHMDIRYFGLNHFGWYTSIKDKKGNELLPK
                     LVEHIKEYGFINGEEGMKNDKKDSWFETNLFTKEIVKTDLTTIPSSYLKYYLFPDYVV
                     NHSDVNYTRANEVIDGREKEVFGSCALIEKQGHSKGSGLKIGIHAEFIVDLATALAFN
                     TQERMLLIVQNNGAIENIQDDAMVEIPCIVGKDGYEPLSIGKIPTFQKGLIEQQLAVE
                     KLVVDAWIEKSYNKLWQALMLSKTVPSATVAKELLDDLIEANKNYWPKLN"
     gene            complement(45696..46025)
                     /locus_tag="KOU88_001236"
     CDS             complement(45696..46025)
                     /locus_tag="KOU88_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK3211139.1"
                     /translation="MVPEMEEKVFSIISEAGDAKSDVMMSLKEIKKGDYNKAKHLLNS
                     ASEKIQTASKHHLELLSNAMNSEDSGTDFLVVHSEDHYSNALFAHSLVSELVDIFEMM
                     DPRINKN"
     gene            complement(46049..47338)
                     /locus_tag="KOU88_001237"
     CDS             complement(46049..47338)
                     /locus_tag="KOU88_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3211140.1"
                     /translation="MEALQNNLRRFLLPIAQKIEKQRHLQAIKEGMISITPIIIVGSL
                     SMLFMALNNMLPEGSAKTLLSENMDTLLIPNKFTMSLLSIYSAFFIAQALAKKYNLNH
                     VEIGMTAVVAQLVVCGQVVDGVLDTSYLDAQGLFVSILVALLVVDITKFMNDKNLVIR
                     FPKEVPSVVNKSFRNLTPMIVCIMLFTAIAAITKNVSGQPLPAIIMNFLAPAISSVDN
                     VFAVTIILFITQLLWFFGLHGAAITSSIWMPIAATYMAENATLIAAGGDPKYVFTIGF
                     YYGFLQVTGSGITLGLVYLMSRSKCKSFNSMGKVVILPSLFGINEPVIFGTPIVMNPY
                     MFVPFVFGPVLVGALNFMALKVGLVGLPIAEPPGFLPPGVAAFLMTLDWKAIVLVFAS
                     IILMTLIYYPFFKIMEKEELNKNAELATTLDDDSFDF"
     gene            complement(47354..47680)
                     /locus_tag="KOU88_001238"
     CDS             complement(47354..47680)
                     /locus_tag="KOU88_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3211141.1"
                     /translation="MNILLVCANGASTGVLVEKMKSFCSEHEKLKTKTINIEATSFEN
                     LKSYIEANDTDVVLVAPQIRFKEDDVVEACKNYKIAVGLIDTKHYGRMDAPSVMKSAI
                     ELYKNR"
     gene            complement(47815..48444)
                     /locus_tag="KOU88_001239"
     CDS             complement(47815..48444)
                     /locus_tag="KOU88_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211142.1"
                     /translation="MQDKILRDKKANDPWARMTTRNGFSADEIISSFQKAIRRNMVEE
                     ACEFAYELYISSPELEDKLWRRILTISVEDIGMGDPSAVIIINNLNQVRKEYSYADGD
                     RPLFFIHAIRYLCACEKDRSSDLLKNIIIKGFAMGKVPEVMDVALDKHTYRGLEMGRD
                     SFHFLNEASIVIPEKEVDNDYKERYLKILEKYKQEEVIDTAFKFNHWQY"
     gene            complement(48659..51316)
                     /locus_tag="KOU88_001240"
     CDS             complement(48659..51316)
                     /locus_tag="KOU88_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3211143.1"
                     /translation="MIYKKDKVMKVLESSYRENEKGITANQLSEKTGIARNNISTYLN
                     QLFNEGMVTKIKGRPVYYIPANLNLNKNELLDTQSELLGIKKGTKVENKIKKDSFETL
                     IGKEHSLRPIIEKCKVAMLYPTNGLHTIIYGETGVGKSMIARYMYDYSIDSGIRKNKA
                     PFVTFNCADYANNAQLLMGHIFGVEQGAYTGAESSRKGLLEIANGGILFLDEIHRLPA
                     EGQEMLFTFIDKGTFKRLGDATKERESKVLIICATTENPTSTLLDTFNRRIPMKIEIP
                     SLRDRTMIERMELVKNFFKEESKSISISIKVHKEIIKSLLLYDCKNNVGQLQNDIKLA
                     VANGYLRYKRDNKEPVYIEKKYFDKSINEVSDDYREKSIKADEVITHGIEYFVFTSLG
                     EEEVINYNDINIINAVNTNLNKSVEMNIADASLFNNVKFKSMCESIRQIIKEDEEIDI
                     SESIFKSMAIYIKSVLDKSSSTNNIDLNQIRRNNRSEFKTALKIVGIIENEFDLFLSI
                     ETVAYITLFIVQAKQDEQNKIVNNINIIVAMHGETTASSMVKAVGDIIGKCSAISFDM
                     KLDKSYDEVIVDFKNLINNIDNKDVLLFTDMGSLNSFDEIIKKEKKCGVRVIPMVTTL
                     TVLEAVQKANMGLPLNDVYNSITNTRKYYFGTNEIQNKENLSKTIIIASHVSEGVDNK
                     TRKILEEKMSRYLDGIDIISVPYKTEKDLSLNITKLKESSNIVAVINEQRINIRGIDY
                     ISKKDIDKDENINKLKNIIKISIGYDDVVEGLKTSLKSSNYNRIFKDIKYVSDELFLV
                     FNIEKKYDKVIGLMMHLAFMVDGLIGNTREIEKLDKEKTLDYHKSLSKIKDIVSQLDK
                     KYNIEINEKECYQILLILEYAEIIEKDYQ"
     gene            complement(51675..52619)
                     /locus_tag="KOU88_001241"
     CDS             complement(51675..52619)
                     /locus_tag="KOU88_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211144.1"
                     /translation="MNREKILEIKNLKQYFHLDKSTTVKAVDDISFDIYKGEIFGLVG
                     ESGSGKSTTGKTIIRLHESTGGEVIYKGNCISDKKTYKFIKKDVNKSMQIIFQDSTSS
                     LNPRMTIADIISEPLKIQGICKNKTDRMNKVYEMLKLVGLDRSYANKYPSDFSGGQRQ
                     RIGIARALSVDPEFIIADEPIASLDVSIQAQIVNLFKKLQQEKNLTCLFIAHDLSMVR
                     HISDRIGVMYNGKLVELADSNELYNNPIHPYTKSLLSAIPVPDPRYAKSRNRIEYNSN
                     GYDCSNEKSLSWIEVSDGHFVYSSKSEINKYQQNLKVV"
     gene            complement(52612..53637)
                     /locus_tag="KOU88_001242"
     CDS             complement(52612..53637)
                     /locus_tag="KOU88_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211145.1"
                     /translation="MEHLLEVNNLSVSFKVEEGEVQAVRNVSFNLKKGETLAIVGESG
                     CGKSVLCKSLMRILPYNGYIKNGEVLLKSSDLVKKAEKEMEDIRGKNISMIFQDPMTS
                     LNPTISIGKQIAEAVIIHQGISKSEAKKRAIELIELVGIDNPEKRFKQFPHHFSGGMR
                     QRIVIAIALACNPDVLIADEPTTALDVTIQAQIIDLIKDLQHKIGLSIIFITHDLGVV
                     ATIADRIAVMYAGKIVEIGTVEDIFYDPRHPYTWGLLGSLPTLDSQDDYLYNIPGMPP
                     NLLNPPKGDAFAIRNKNALKIDYEKEPPMFKINDTHSAATWLLHPDAPEVDVPVRVNC
                     GRVISNE"
     gene            complement(53712..55280)
                     /locus_tag="KOU88_001243"
     CDS             complement(53712..55280)
                     /locus_tag="KOU88_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3211146.1"
                     /translation="MKLKKLKVLSLVMILSLMAGCSSGGDKDKKADTPKDGKVLVYGS
                     NDYTSINPALYEHGEINSLIFNGLTAHDENNKVVPCLAKDWKFDEATNTYTFNLRDDV
                     KWHDGEKFTANDVKFTIETIMNPDNASEIASNYEDITKIDVVNDNTIKITLKAPNTAM
                     LDYLTVGVLPKHALEGKDIATDEFNQKPIGTGPFKLEKWDKGQSITLVKNSDYFVKEP
                     GLDKVVFKIVPDDKAKAMQLKSGELDLAQITPKDMSNFEKDEKNFKVNIMKTADYRGI
                     LYNFNSKFFKDKKAKGLPNALSYAIDRKAIVDSVLLGHGVPAYSPLQMGPYNNPDIEK
                     FEYNPEKAKQEIEKLGWKLGSDGIYEKEGTKLAFEITAGESDQVRVDMAKICAQQLKE
                     IGVDAKAVVVTETDWANQDAHLIGWGSPFDPDDHTYKVFGTDKGANYSAYSNPTIDKI
                     LQKARETEDKDEKLKLYKQFQVEMTKDMPYTFIAYIDAIYVGKPNIKGLTPDTVLGHH
                     GVGIFWNIADWTIE"
     gene            complement(55393..56304)
                     /locus_tag="KOU88_001244"
     CDS             complement(55393..56304)
                     /locus_tag="KOU88_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211147.1"
                     /translation="MKPQYSDFEIVGENYILVAEDEHIETKKTLSKKIKELPYISIII
                     LSIIVIGSVFSSFIMTHEPTYMDLASSNLAPNKTFLFGTDSMGRDIYSMIWYGGKISL
                     FIGLFSTVISTVIGIVYGSISGSASELVDDAMMRFTEIILSIPSILIIIFVQAILGNS
                     NPVSMSIVIGITSWMNISKIVRTEVRQIRNSEYILAAKSMGGGFFYVLKQHLLPNFVA
                     SIMFMVVTNIGAAIGTESTLSFLGIGLPIEIVSWGSMLSLSEEALLSNRWWIILIPGI
                     FLVTTLVCITNIGNYIRKNNNKKSSNL"
     gene            complement(56288..57274)
                     /locus_tag="KOU88_001245"
     CDS             complement(56288..57274)
                     /locus_tag="KOU88_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211148.1"
                     /translation="MLKDILKKLLQFILVMFLLSFIVFYMARLAPGDPLISYYGDGVE
                     RMSTQEKENAMKKLGLDEPIYSQYIKWISNASKGEFGISFKYKQNVTSVINDVYINTI
                     ILGGSGYILTFVLALLLGIFCTLHEDKLIDRIICKLGTITNCIPSFWVALVLILIFSI
                     NLSILPSSGAYSMGEESSILSRISHLILPLTVLILSHLWYYTYMIRNKLLEEIREDYV
                     LLCKAKGLNNRTIVFKHCLRNIMPSYISIMAISIPHILGGTYVVEKVFSYPGLGTLCF
                     ESAKYHDYNMLLVLCLITGALVVFGNMLAQIINNKIDPRMKYDRGDTNEATI"
     gene            57634..58035
                     /locus_tag="KOU88_001246"
     CDS             57634..58035
                     /locus_tag="KOU88_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK3211149.1"
                     /translation="MLLKELYSKTMYTVEENFKENGLTHQQIIVIKLIAHNQELTISQ
                     LCDEMSLAKGTVSGIISRLEQIGYIEKFKKSNDKRNTYVKFTTTGFEFATNFKIKMQE
                     SFDDIFKNCDENELSDLVKNLRNILAKVKER"
     gene            58038..58436
                     /locus_tag="KOU88_001247"
     CDS             58038..58436
                     /locus_tag="KOU88_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03987 family protein"
                     /protein_id="HBK3211150.1"
                     /translation="MNYKLILAIVFITSALIFYTIGVFGERKAKILKKKHVIIFWLGF
                     IFDTLGTFTMSNIANSHTFEVKSALSQNLHSITGLLAIVLMLFHASWATFVLYKDDEE
                     KKKFFHKFSIVVWTIWLVPYFIGMFIGMAG"
     gene            complement(58884..59108)
                     /locus_tag="KOU88_001248"
     CDS             complement(58884..59108)
                     /locus_tag="KOU88_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HBK3211151.1"
                     /translation="MREKVEKVLEEKIKPVLQRDGGDVELIDVNENGVVLVRLQGACS
                     GCPGATMTIKAIIENVLVSEVPGVTQVLGV"
     gene            complement(59143..60510)
                     /locus_tag="KOU88_001249"
     CDS             complement(59143..60510)
                     /locus_tag="KOU88_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3211152.1"
                     /translation="MKEYIINNVEEIREELIDLSKKIWENPELAFEEKYASSIQKEYL
                     KSKGFKIEEVENLPTGFIASFGEGKPVIGILGEYDALPELSQCVSAERKPLVEGKAGH
                     GCGHNLLGVAGVGAVVSIKKLIEENKFNGTIKYFGCPAEEEGGGKTVMCINGCFDDVD
                     CAFTWHPFDINAPWRGGSLANLSVKFKFKGITAHAAQAPHNGRSALDAVEIMNVGANY
                     LREHVIDSIRMHYVITNGGGRPNVVPGFAESWYFIRGKKAKDAEHVLDRLIKVAQGAA
                     MMTETEMEYKVTDGIYDYIPNQCLTDLVYDNMVFIGCPKNTPEEEEFAKKLCDTLTRE
                     ERLGVATSLQNDKSIVESYIHKEIVDGDKDKGLAGSTDVGDVSYVIPVAQFAMAAWPV
                     GIASHTWQSCSSAGSNIGFSAMINSAKVLACSAYDVFMDTKIIDEAKIEFDKSLDGQK
                     FKPLV"
     gene            complement(60594..62129)
                     /locus_tag="KOU88_001250"
     CDS             complement(60594..62129)
                     /locus_tag="KOU88_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211153.1"
                     /translation="MLNNLSNININENNLIKNQYSISLLKECLNCKVIDEREVYNIQQ
                     EVSLILMDLIKKYTNGQSTSVKTEVAEKLLISIWYAIDAYINKLGDIEKRVVELTAKN
                     VKKVYLGGIEILEEELVRLKDFYKLMMSRKLDTNSIAYNDTLMELSSFFKSYIVKFEA
                     QDVPVSIDYPLALDDMDVKGIYYVKNYIESIDIENRFCNLFKKKDREKLFYDYGMTYK
                     IDCDVILVNLFELIMNNCIFSTILGNEVTNLEISKYEYEFLEKQFKNMYNNITEDKVI
                     DSEESNIIELIEVDDSFNTEVDSNLDYNDFEEINREIRINKKITLLLMEAIEVLIKRL
                     SIEDEDVIRYIKKYEKIFIESVLSSIKSNTLKSMVTVSKNKNEHLEDYIVDDESKLDD
                     ESFREIFNEILDSTSIIEKIRIIKENINAKKDFIDILESECLFGEEYLMLFASLSELE
                     LAILGSVVFYEDIRMREINILEFMLNEKTETTLWKIEYIKFMKRQSEDKIYSIEEHMN
                     KIN"
     gene            complement(62152..62586)
                     /locus_tag="KOU88_001251"
     CDS             complement(62152..62586)
                     /locus_tag="KOU88_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211154.1"
                     /translation="MISPIILSSINQNLKEIERNELLETNIESGDYGLALSESDVKDI
                     INSRDNTLKGYGRIELDIKVTKQLIENIYTSQYTNVDNYLEAINDMQEIFYYLKNETD
                     DKICDDEIIEILGEFYEKFSGNMDNVRGEADEFAKKFKFGEV"
     gene            complement(62846..63757)
                     /locus_tag="KOU88_001252"
     CDS             complement(62846..63757)
                     /locus_tag="KOU88_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="HBK3211155.1"
                     /translation="MNKKIELIGNFASDWIRYSDYEYKITEEDELYIVPTEDAVFTMY
                     NPFDVADDIIVDIIRIGQEALQDISKETKEMKLKKEVLEFVKKYGLLGLIYSSVYNRD
                     IVGEERVLMIEKNYITKENILSTDEYVNMFIPFASDEDVYFKKYRRGIDVSKREESPK
                     FFGKRPLILDLVFSKFYTEQLDWIVSFAKDMCKHFNQICVYKNTSNLLTESVTIMSGG
                     FNPQKIGFSISQLDKPIIAWEFDSLKTAIETIYAFAITSEPSSLNKCKYCGKIYIPTN
                     SKSQYCSPSCRNCSNVKKSRSRAKKDK"
     gene            64053..64406
                     /locus_tag="KOU88_001253"
     CDS             64053..64406
                     /locus_tag="KOU88_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBK3211156.1"
                     /translation="MDRKRELKQLYKEMKFDTGVFIIKNDITKKIYLGKSNDIKSKFN
                     SLKFQLGAGSCMIKELNNEWKKYGEKAFTFEVLELIKHDDNKTEKDYLEELDILEMVW
                     LEKLKEDNTYEIYSI"
     gene            complement(64625..65566)
                     /locus_tag="KOU88_001254"
     CDS             complement(64625..65566)
                     /locus_tag="KOU88_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp25"
                     /protein_id="HBK3211157.1"
                     /translation="MRISKKVLALGISALLLSVSFPTSINALDKIENIQGVDKYETAG
                     LISDKQDFTTAVLINADSTMVDGIAASGLAGVNNAAILLTNKDDIPEATLQRLNRVTK
                     IYVIGGENSISKDVEKMLLMRRMQVIRIDGVDRVDTSYKIAGEIEKIKNSDKMFLVNG
                     FKDEADAVSVASVAYRDGAPIILTKDIPSAEEDTDLDPWFGVSPVPVYAIGGESTLSD
                     YIVSRYRATRIGGVDRYQTNKNVIEKFYNGAKEFYITSGDDLVYALVASPLAKNAPVV
                     LVSNKSDKSILSGASKVTAIGISDKSIIEQCLDAVKK"
     gene            complement(65667..66902)
                     /locus_tag="KOU88_001255"
     CDS             complement(65667..66902)
                     /locus_tag="KOU88_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBK3211158.1"
                     /translation="MKILHIITQKPNSTGSGIYLSGMIKGFEKIGHKQAVIAGIDVND
                     DVNCFPSEVSFYPVKYNCGELNFPVVGMSDSMPYESTRYKDLNIDMINRLKYQFKVNI
                     DKAMNDFKPELIICHHLYLLTAFVREMVKDIKVMSICHGTCLRQLNTIDLEKEYIIAN
                     IRKLDLIFALHENQKYDIIKTFGVSESKVVVIGSGYNDDIFYNKNYKIKDDKIKIVFA
                     GKICKSKGLIPFIKAISKLKYSKDLIEVNFAGTGSDIESYNEIVKLASKSPFKMNFLG
                     KLEQRDLAELFNRSQIFVLPSFYEGLPVVVLEALSCGTDVITTDILGVKEWIGSEINN
                     SGKIEYVSLPFMEKEGIPKDEELYDFENNLYNAIDSKIQSLLNNSNKKTSVDMSKKTW
                     DGLAYRINEVILMDELCLV"
     gene            complement(66946..67800)
                     /locus_tag="KOU88_001256"
     CDS             complement(66946..67800)
                     /locus_tag="KOU88_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211159.1"
                     /translation="MALNIRNYSLLCNQGTAKFNEDVVGINPFGAWVLDGATGLNGKN
                     LVSTESDARWYVQWWNRYLYKNINKEESLKSIINTGIIEVKKEYELRLNGFKVEKLDL
                     PSSSIVVVKFHENKVEYFLLGDCALFIKNGDSKVIKDRSICKFDNTVFDEMSKLSNLE
                     EMAFDEIRTSVMDTIVSNRLKKNTKEGYWILDFDEEAVENSIYGYIEIKKDFQLMLTS
                     DGFTSACDRYNLIKEEELIRIAEKFGIGYIHNKVRDFEDNDYKAVKVPRFKVKDDSSC
                     LYLDIYND"
     gene            complement(67928..69103)
                     /locus_tag="KOU88_001257"
     CDS             complement(67928..69103)
                     /locus_tag="KOU88_001257"
                     /EC_number="2.1.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolecarboxamide
                     formyltransferase"
                     /protein_id="HBK3211160.1"
                     /translation="MARELELKYGCNPNQKPSKIYMKNGELPIEVLNGKPGYINFLDA
                     FNSWQLVKELKEATGLPAATSFKHVSPAGAAVGVPLSDTLKQIYFVDDLELSPLACAY
                     AMARGADRMSSYGDFIALSDVCDKETATIIAREVSDGIIAPGYTDEALEILKGKRKGN
                     YNIVKIDENYTPEPIETKDVYGITFEQGRNEILINEDLLKDIPTDNKIFTDSAKRDLI
                     IALITLKYTQSNSVCYAKDGQVIGVGAGQQSRIHCTRLAGNKADTWYLRQHPKVLNLK
                     FKKDIGRPDRDNTIDVYLSDDYMDVLADGIWQNFFEEKPEPLTGEGKRAWLKTLTGVA
                     LGSDAFFPFGDNIERAKRSGVSFIAQPGGSIRDDNVILTCNKYNIVMAFTKNRLFHH"
     gene            complement(69202..70086)
                     /locus_tag="KOU88_001258"
     CDS             complement(69202..70086)
                     /locus_tag="KOU88_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBK3211161.1"
                     /translation="MKFVTFCSSNEEKIGVFNSETNSIYEINSLGLSKLYTDMNDFIE
                     NVSTGDLEKIKNNSFENAKCYKLEEVKLCSPIVRPKKDIICLGLNYKDHVNEIPDGVI
                     KNVVMPDYPIYFSKRADKIIGVDDKISLHGDLVEKLDYESELAVIIGKEGINISKEDA
                     YEYIFGYTIVNDISERALQDKHVQWFRGKSLDTHTSMGPCIVHKEEFEHPLKLDISSV
                     VNGEVRQDSNTEYFIFDIPTIINDLSRGMTLKPGDIISTGTPAGVAMGMNPQVYLKHG
                     DIVECKVEGIGVLKNIVD"
     gene            complement(70318..71004)
                     /locus_tag="KOU88_001259"
     CDS             complement(70318..71004)
                     /locus_tag="KOU88_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK3211162.1"
                     /translation="MKYSYKKCIIDSILLMFIVQILRMILNYVLLSQFEFTLENFNII
                     NLISFTLVGLSLILFLKDNSLYNKVRNRKITEAFEENKNNILIEKCKLILFVVVLSLA
                     IIVTYCTKGYVLFNVTMMTLSVLIVPIFEELFFREYIWNYLSNFIKSKSKIICITSIL
                     SGIYNIGYIDVIRNYVILYNNSSYTFEVIISKIMIGTVFGIVLGLVKYRFRDVGFCIL
                     LRSLFAIFIR"
     gene            complement(71032..71343)
                     /locus_tag="KOU88_001260"
     CDS             complement(71032..71343)
                     /locus_tag="KOU88_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBK3211163.1"
                     /translation="MGIFKTKMDEDWKVNYIKEFNEMRDSYESKLQKKQFEVDSLKSE
                     LDRLRSYKNSLKPKEKQITDDDINNIKSLRRDGLSYKEISNQTSWSKATVSRVLNGLY
                     D"
     gene            complement(71532..72053)
                     /locus_tag="KOU88_001261"
     CDS             complement(71532..72053)
                     /locus_tag="KOU88_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBK3211164.1"
                     /translation="MIGFLKKRRSIRKYKDVEVEKEKLDKILKAALLAPSSKGLRTWE
                     FIVVDDKEKLINLSQCRTKGGGFFLKNAPLAIVIIADKEKNDVWIEDASIAASYIQLQ
                     AHELGLGSCWIQVRNRMHDDNIEADKYIREELKVPSKYSVECIISIGYPDEEKKAYSD
                     SDLDYKKVHFNNF"
     gene            complement(72150..72644)
                     /locus_tag="KOU88_001262"
     CDS             complement(72150..72644)
                     /locus_tag="KOU88_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3211165.1"
                     /translation="MIRKANMNDLESIMKIIKSTVEEMKTYNNTQWDENYPLEKDFVS
                     DIKKQDLYIYEVDGEVAGFICLNYEEPEEYLGLNWSSNKKAMVIHRMAVNPNFRKTGI
                     ASKLVDFAEKLAVENNVSYLKSDTYSINSKMNLLLTKCGFIKIGEMSFLGKEKSFYCY
                     DKIL"
     gene            complement(72678..73151)
                     /locus_tag="KOU88_001263"
     CDS             complement(72678..73151)
                     /locus_tag="KOU88_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3211166.1"
                     /translation="MVVSVEVCLIKTLDSNILREVGTLSRAVNSINDIKYKELKLQKG
                     QFTFLTRICENPGINLVELSNMLKVDKATTTKAIQKLIKAGYVDKKQDEFDKRGYNLT
                     PTDKSLEVYELIIEEENRSIEICFDNFTDEEKQVVTKLLEKMSKNVENEWFKVKR"
     gene            complement(73477..74472)
                     /locus_tag="KOU88_001264"
     CDS             complement(73477..74472)
                     /locus_tag="KOU88_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate/isopropylmalate dehydrogenase family
                     protein"
                     /protein_id="HBK3211167.1"
                     /translation="MYKVTLIPGDGIGPEVAKAMKKVVEATGVEIEWEEVNAGEAVIE
                     EYGTPLPEYIIDSIKKNKIAIKGPITTPVGKGFRSVNVTLRQALDLYVNLRPIKSFKG
                     IKSRYEDVDLVVVRENTEDLYAGIEHKIGDYAAESIKIITRSASERIVDFACNYVKDN
                     KRKKVTAIHKANIMKMSDGLFLDVFREVASKHGVEYDDLIVDAAAMNLVLNPENYDVM
                     VMPNLYGDILSDLGAGLVGGLGIIPSANIGKDCAIFEAVHGSAPQIAGQNKANPTALI
                     QSSVMMLRYLGEYENAQKIETALEKVFLEGSKLTVDLGGSASTTEFADEVCKYIV"
     gene            complement(74494..76419)
                     /locus_tag="KOU88_001265"
     CDS             complement(74494..76419)
                     /locus_tag="KOU88_001265"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase"
                     /protein_id="HBK3211168.1"
                     /translation="MGDNIVYKIIKKHIVDGEAVAGSSIGIKIDQTLTQDSTGTMTYL
                     QLEAMGIDKVKTKRSVAFVDHNMLQQGFENADDHKYIQTVADKYGVYFSKPGNGICHQ
                     VFLERFSTPGDTLLGSDSHTPTAGGVGMMAIGAGGLDVALAMAGGAYYIKAPKVCKVN
                     LVGKLNNMVSSKDIILEVLRKQTVKGGVGKVYEYGGEGVKSLSVPQRATITNMGAELG
                     ATTSIFPSDEKTLEFFKSQGREDAWVELKPDADAVYDEEITINLDELKPLAAKPHSPD
                     NVDEVENIGKIKIDQVAIGSCTNSSYEDLMKVAQILKGNKVHKDVSLVIAPGSRQVME
                     MIARNGALADIISAGARILENSCGPCIGMGQSPGTDSVSLRTFNRNFYGRSGTLSAQV
                     YLVSPEVAAVSAIKGVLTDPREFDIKFTNLDVNEFLIDDSMIIKPADVGSDVEVVRGP
                     NIKPFPLNTELSQSIGGKVILKTEDNITTDHIMPSNAKLLPFRSNIPYLANYCFNTVD
                     TEFPQRAKDNNGGFIVGGDNYGQGSSREHAALAPLYLGVKGVIVKSFARIHKANLINS
                     GIIPMEFCDEKDYENISLLDNLEIPNILDNLGSGILEVKNTTKGTSFKVKVELSAKEV
                     DVLKAGGKLNYTKNQAN"
     gene            complement(76444..77637)
                     /gene="nifV"
                     /locus_tag="KOU88_001266"
     CDS             complement(76444..77637)
                     /gene="nifV"
                     /locus_tag="KOU88_001266"
                     /EC_number="2.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homocitrate synthase"
                     /protein_id="HBK3211169.1"
                     /translation="MCVISKDRAKEIKIVDTTLRDGEQTAGVVFANREKIMIAEMLSD
                     LGVDQIEVGIPTMGGDEKNVIKHICSRNLKSDIMAWNRAVIKDVEESISCGVDAVAIS
                     ISVSDIHIENKLRTSRGWVLENMAKTVEFAKKNGLYVSVNGEDASRADIDFLTEFINV
                     GKQAGADRFRYCDTVGVMNPFSIKNAIETLYERTNFDIEMHTHNDFGMATANALAGIA
                     AGANYVGVTVNGLGERAGNAALEEVLMALKCVYKCDLNNIDTRKFRGICEYVAQASGR
                     ILPTWKPVVGDNMFIHESGIHADGALKDPHNYEPFDPSEVNLERKIVIGKHSGRAAVV
                     NKLSEYEMYISPENATKLLNAIRATSIRLKRSLMDKEILQLYCDILAHEKGTTEEEAV
                     RGSYI"
     gene            78100..79209
                     /locus_tag="KOU88_001267"
     CDS             78100..79209
                     /locus_tag="KOU88_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK3211170.1"
                     /translation="MDFKSLGISENTINILKKSGITTPTPIQKESIKLIKEGKDVIAE
                     AQTGTGKTLAFLLPIFENISLDINDIQVLILSPTRELAIQITEEAMKLKESKDVSILA
                     AYGGKDIGSQIKKLKGNIHMIIATPGRLLDHLNRKTIDLSKLKTFVLDEADQMLLMGF
                     KNEVEAILKETSNKKQTLCFSATINSQVKKLAYRYTKNPVVVSIQKEEITLNNIKQEV
                     VETTDRKKLDALCKVLDEDNPFMAIIFCRTKRRVDNLEEALAIRGYNCQKLHSDIAQS
                     KRERIMKSFRNLDIQYLIATDVASRGLDISGVSHIYNYDLPETPEDYIHRIGRTGRAG
                     EEGYTCAFIDPKNERMLSEIETAIESKISRRIIEL"
     gene            complement(79586..80770)
                     /locus_tag="KOU88_001268"
     CDS             complement(79586..80770)
                     /locus_tag="KOU88_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211171.1"
                     /translation="MQKSVKKAKVTGSMLAIFGVASVLFSSHAGGGFATGNQETQYYV
                     QYGWTAPLMAILAMIILTATMREVIIMYNNNNCRNYKDLFCELWRPYPKLEIIWEIYY
                     YLMVLIAVSAVIAGAAAVFQSIGVNYFVAVFIIGVVLLVFTIFGAMLVSKAATAMTIA
                     ILVCTLTIFIVGIKAKVPEITEILSNRTSFTPGYIKPILNTFIYAGFQSVVIPTLAGC
                     SRPLLKNSKEATKAMIISFVMNAIALGLAVTMLMGWYREIIAAGQTTLPTLYVAGQSG
                     NHTIYIIYNVALFLCLMSTGVTTIFGLVNRFEDHKALSFLSSRMKRRVFTACAIMVVS
                     MLISLTGLSNIVKYGYGYCGYLGLFTIVIPFLTLGHYKNKKFAKENPEAKWPAELNEN
                     VN"
     gene            complement(81372..82187)
                     /locus_tag="KOU88_001269"
     CDS             complement(81372..82187)
                     /locus_tag="KOU88_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3211172.1"
                     /translation="MERLKIQVLVDNNTYIDRYFVGEPAVSYYIEIDGNRILFDSGYS
                     DVFISNAEKLNIDLGNLTHVVFSHGHNDHTRGIQFLENRYDLSTVELISHPNCFIPRK
                     HGEKSIGAPFSAEEIKNIFMYNPKDKPFNLSKNCVFLGEIPSINDFEKRAKIGKCKIG
                     DLWEDDYVLDDSAIVCKTDKGIFIVTGCSHSGICNIVEYAKKVCGDDRVIGILGGFHL
                     FELNNRLDSTIQYLDKEEMRMLYPCHCVSFKVKAKMNEILNINEVGVGLTISI"
     gene            complement(82484..83926)
                     /locus_tag="KOU88_001270"
     CDS             complement(82484..83926)
                     /locus_tag="KOU88_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBK3211173.1"
                     /translation="MSIYKCSVCGYIYDESKNDKTWDELSEDWECPVCTKGRSYFGKI
                     STVYYEEDEKIAEDIVEDESKLNTEKEGDLNYLSTYLRRDDEVEKHMDIIHEMAVTGK
                     SIIEPMRTKLPVISWDDILIMGAQLNPLPLNEHDEVNTTTIIGKKAKKPMIIENPVYI
                     SHMSFGALSKELKIALAKGAAQNKTAMCSGEGGILPEEKEASYKYIFEYVPNKYSVTE
                     ENLKNSDAIEIKIGQGTKPGMGGHLPGEKVTEEIAKVRNKPVGQDVISPSCFEEIQSK
                     EDLKKLVDELREVSEGRPIGVKISAGHIEKDMEFIAYAKPDFVTIDGRGGATGASPKL
                     LKDATSIPTIFALYRARKYIDTHGLDIDLVITGGLRISTDFAKAIAMGADAVAIASSA
                     LMAAACQQYRICGSGKCPVGVATQDEELRKRLHIENSANRVANFLNVSLEELKTFARI
                     SGHKDIHDLSVDDLYTVNSEISNYTNIQHV"
     gene            complement(84053..84439)
                     /locus_tag="KOU88_001271"
     CDS             complement(84053..84439)
                     /locus_tag="KOU88_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="desulfoferrodoxin"
                     /protein_id="HBK3211174.1"
                     /translation="MCSEQKFFICETCGNLVGMIQSGGVPIFCCGKPMKELVPNTTDA
                     AVEKHVPVIEVDGNNVTVKVSSTTHPMTKEHHIAWVYLMTEQGGQRKCLAVDGEPVVK
                     FALNDDDKVISAYAYCNLHGLWKAEL"
     gene            complement(84476..84865)
                     /locus_tag="KOU88_001272"
     CDS             complement(84476..84865)
                     /locus_tag="KOU88_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBK3211175.1"
                     /translation="MKFSKQRELILNEILNNPVHPTADYLYENLKKDNPNLSLGTVYR
                     NLAQLTEHGFIRKVSIPGYPDRFDGRIDNHYHIICEVCGEVYDLESEVLNNLQELISE
                     ETDIKITSYNISFKGICNNCKRCSQVG"
     gene            complement(84897..85433)
                     /locus_tag="KOU88_001273"
     CDS             complement(84897..85433)
                     /locus_tag="KOU88_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBK3211176.1"
                     /translation="MNLKGTKTEKNLMAGFAGESEARNKYTYYASKARKEGYNQIAAI
                     FEETANNEKEHAKLWFKLLHDGMPSTEENLKDAAAGENYEWTDMYAKFAKEAREEGFD
                     KIAYLFEAVGKIEKEHEERYLKLLENLNEGKIFKRDEEVVWQCQNCGHVYVGTEAPEK
                     CPVCDHPKAYFNIKAENY"
     gene            complement(85810..86592)
                     /locus_tag="KOU88_001274"
     CDS             complement(85810..86592)
                     /locus_tag="KOU88_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211177.1"
                     /translation="MLDIITTEFQKIKRYNILWIGVVAVLFSALLAVFQVVSSHGSDP
                     LTYESFANGVIWNNFSLSFPFGITLIGGYLINREYTDQTLKNILTVPISLRKLLVGKL
                     IAVGGITVLLSLFSFLCTFILGLLFCNINISVTLVVKSLVQILSVNLYCYVAVLPIIA
                     YFGRKQNAFLTGVGIAFVYGFCGVFVAGRNLTDFYPITAGLGLVGYNNGAGTVYQPLI
                     GAMTLIVILILTTILLVFTPNYDKVMTISKKKGIKHKKYSHK"
     gene            complement(86602..87372)
                     /locus_tag="KOU88_001275"
     CDS             complement(86602..87372)
                     /locus_tag="KOU88_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211178.1"
                     /translation="MKELLDIISCEFSKLKRLKFILISILGACLFPIPATILIAKDNL
                     PFEQLFKLVVNFGYFLLLPIVLSIVASQLFFIERDNDVLKNLATVPVQKGKLALAKLA
                     VLLFISLFYSVAGLGATIIGGFIVGIVEGVAVKLGMSIAFGIMFFVTVLPVVVLIVYF
                     NRSYIFSIILSFVYAIFNFSISLNIINFEPNNPILSVLPAPVIMRWWMAFWGDPTGEY
                     TALRQPYLLSTPACVGILCLITIIAVLLICMIYKKQEN"
     gene            complement(87356..88279)
                     /locus_tag="KOU88_001276"
     CDS             complement(87356..88279)
                     /locus_tag="KOU88_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013273760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211179.1"
                     /translation="MNNLIIETKNLTKQYGAQKSVSNLNIHVQKGRIYGLLGRNGAGK
                     TTTMKMLLGLTKPTTGEIKIFGQDIHNNEKKLLPRIGCLIESPGFYPNLTGTENLKIF
                     ARLRGIPKKNAVESALDVVGLPNNDKKLFSQYSLGMKQRLAIALAIMHDPQLLILDEP
                     INGLDPIGIAEVRTFIRDLCTERGKTILISSHILSEIALLADDIGIIDHGILLEEESL
                     AQLEEKNSKYIHFAVSDAAQAARLLETQLNLKNFKVADNYNIMLYDTDVSVAEINRAF
                     ILNNIEVSESHLCEDTLEDYFKKVTGGEGIA"
     gene            complement(88427..89362)
                     /locus_tag="KOU88_001277"
     CDS             complement(88427..89362)
                     /locus_tag="KOU88_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3211180.1"
                     /translation="MKMDEQTIILFLLLLSIGLLFLSIFAFSKLGHIYKRLKDIEEIL
                     ADVQIGDENRKILIKPCDVMAPLVYQLNEIVYDYENKLLSLKKSDKASKQLMTSLSHD
                     VRTPLTTLIGYMDAVHSGIVIGQEREEYLEIARRRAYDLKDYIDVLFDWFRLNSDEFT
                     LSIESVEIAELSRNILKDWIPIFHEKKLNFEIDIPENRLMVNLDPDGYSRVVNNLVQN
                     VLAHSKARQIKITMSEDSRMVLLRVEDDGVGIARENLPHIFERLYKCDKGRSEKGSGL
                     GLSIVSQMVERMGGQVSVESEIGKYTVFTVSLPLI"
     gene            complement(89359..90051)
                     /locus_tag="KOU88_001278"
     CDS             complement(89359..90051)
                     /locus_tag="KOU88_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003020373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3211181.1"
                     /translation="MNKVLIIDDDKDLCILLKKSISIEQIEANYCHSGRDGLVELSKQ
                     DYQLVVLDVMMPGMDGFETMEQIRKYSSIPILMLTSKSDNYSKVHGLRAGADDYLTKP
                     FEITEFTARVLSLIRRYTRFNPKNEEPQQLSFKGLLIDLDQHTVTTNGEPMLLPPKEF
                     GVLLYCARHQGKILTKQQIYEAVWGEPYVYDDSNIMAIISRLRKKIELDPSSPIYLQT
                     IKGIGYQFNTEV"
     gene            complement(90712..91560)
                     /locus_tag="KOU88_001279"
     CDS             complement(90712..91560)
                     /locus_tag="KOU88_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK3211182.1"
                     /translation="MYITKVLNNSLLLAKDDNDEEIILMGKGIGHNYKAGSELNKKDI
                     EKIFVLHDENIKKSIIQLATEIDAEYFGIAQMIIAYGIEKYNLKLMNHIYLALTDHIA
                     FAVRRFKEGIMIENHYLFEIKEFNPKEYDIGKYAITVFKEVLGLDLSEEEIGNIAGHF
                     INAQQDNPYSDRNKRSAKIVNAILQIVHYHFSIVYNKESFYYRRFVMHLKAFSQRFLA
                     NEPSREKIDFIYEQVQKNCKEEYECVKKVGAYMYKEYSRELPRQEELYLMIHIHKILG
                     ELCENS"
     gene            complement(91588..92994)
                     /locus_tag="KOU88_001280"
     CDS             complement(91588..92994)
                     /locus_tag="KOU88_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK3211183.1"
                     /translation="MNTGFPKDFLWGASSSAFQVEGAWDKDNKGKTVADYNSFKKSHL
                     QADTKVASDFYHNYEEDIELMKELGMKTYRFSISWARIIPDGEGEINQKGLEFYNKII
                     DKLIECDIEPFVTLYHFDLPFKLVEKYNGWESRETVYAFERFAKICFKHFGDRVKYWQ
                     PHNEQNLIVRVEERINIYDETDSWKIDKMRAQMDYNLCLAHALAVNACHEMIKESKIG
                     AAVSSSVTYPLTSKPEDVYAARMNDNFKVYYMLDMHHYGEYPGYYMKYLEKRNIVPHM
                     EDGDKEILKKAKMDFIAVNYYRTNCAEALPEDSQHPFGLREGTVDFSMYGLFKMSMNP
                     NLEASEYGAAIDPSGLRVALNEYWQRYHLPVIITENGLGAKDILEDGKIHDDYRIDYL
                     RSHINACKLAIEDGVEMIGYCPWSFTDLLSSSQGFNKRYGLVYINRTDHEVLDLKRIK
                     KDSFYWYKEVIENNGIVK"
     gene            complement(93504..>93757)
                     /locus_tag="KOU88_001281"
     CDS             complement(93504..>93757)
                     /locus_tag="KOU88_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3211184.1"
                     /translation="SWSEFIRQLEYKANWHGRQIVKVGKFFASSQICNKCGYKNEEVK
                     DLNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT        30458 a        16684 c        10066 g        36549 t
ORIGIN      
        1 tttttatctt tttaatatga ttaaagacta aagttattga catagcacta gttattattt
       61 gtagacaaat tagtccaaac ccataggcac tattaaaatc tgttgtccca ggatttgcta
      121 ttgaagtaca aaataggtat attggatatg caaaaattga tataattgct gaaaacaata
      181 tgtgcttact attgtcttga cttatagcaa atacatttaa attgaataaa actcctgtat
      241 ctgtatctaa caatacatca taagtattgt ttaaatcata aaatatagta gtcttagaaa
      301 aaaatatctt agttattatt aagtaagtta ttacaactaa tataaacaaa aacatctcgt
      361 ttttatattt taatatttta ctcatcaata tatcaccatc cattcattat ataggatttg
      421 ctgacaccta caatttattc cttatattta atagccatct tcataatgtt cttacttgtt
      481 ttattgtaat tgaataactc tttatttaca accacaatat ttactttatt gatgttataa
      541 tcagtcaagt attgtttata taacatagat tagtgttgta taaaatgaga atttgtaagc
      601 aatattaatg taaaatattt gaaaaacttt atataaaaat atacaatgtt gcttatggaa
      661 ttaaactata acaaattaaa gcataattta aggagacaaa attataatct gtctccttaa
      721 atattaaaac tatattttaa aacattacta aatactatac aaatttcaaa tatagtataa
      781 aattaattag actttaacac tattagctcc atcttcttcc cattttttaa tttcttttaa
      841 tctatctatt ataggtaaat gctgagtaca ttcaacttca cattttccac aagatataca
      901 ttctttagct tttgccttac tattcattgt gtaattccaa tgtcctaagc cataaactaa
      961 ctttgtcatt tcttcatcac tctttttaaa catctgcttt tcattataaa aaagcatata
     1021 ggctggggta ttaatacctt ttggacatac tttacaataa ccacaacctg tacatatttc
     1081 gttcatattc ttatttaatc tagtctcaat atcatgtata tcctcatctg aataaattct
     1141 attttcgtct gcaattttac atgcatcatc tatatcttgt tttttattaa accctatcaa
     1201 agatatactt atttgtgaaa ttcctatgtt gaatcttaaa gctgattcta tagtactttc
     1261 gccatctttt gatagaaaag aaagttcttt attatacttt ggaatagttc caccacttaa
     1321 tggattcatt gccacaacac catatccatt atcaacagca tatttggcac cttttagcct
     1381 atatggaaag tttaatatat ttattcccat agttacacct tcaaacttat tttcacttag
     1441 aatatctata acctcatctc ctggttgatg agatgaaaat actatatggt ctatcaatcc
     1501 ttcttcttta catttcaata atccttcata ttgacctcca ggtctcattg ctagttcgta
     1561 atgttccatc tttctaatat tccaaacatg ataaaaattt attttagata cgcctaatcg
     1621 ttctattgat ttttttacag cctctatagc tttttctgat gtatcacatg cttttggctt
     1681 ttctttagtt gatacataaa aatcggtctt accttccttt atcatttgtc taaaggctag
     1741 tccaaatata tcttcacttc tgtcatcaca ataccctggt gctgtatcaa agtaattaat
     1801 acctttttca tacgcatatt tgactaaatc agcattttct tgattacttt tttctaaatc
     1861 aaaccttaat cctccatagc caactactga aaccattttc cctgtctttc catattcaac
     1921 gtatctcatt gtaaattcct ccttagatat attaagactt aatttcttta tagaaaatat
     1981 tataccataa ataattttta taaattattt atggtataat atttttttta taaattatat
     2041 ttttttataa cttgtatttt ataactaagt taaaaactat aaaaaggttc aatatggact
     2101 attacttgag cattttcatt aatttcttct tgtatttgtt tctcaatttt atgtgttaaa
     2161 tcatgagatt gctctacgct tataaatggg tctaccatta catgcatgtc aatataaata
     2221 gaacttttgc tacctctact tctgatattg tgaacatccc ttacctcatt aaattcaaac
     2281 acaatttctt ttatataatc ctcatctaca gccactctat cgaccaaaat tccaatagat
     2341 ggcctaaata ttccataagc cgaataaatt atgaatgcag aaataataat aggaactata
     2401 gattctatta ttactggaaa tcctaactta acaccaacta aagtaaccaa tacacctaga
     2461 gacacaaata tatcacttct tgtatgcaat gaatccgaaa tcaaaacata actatttagt
     2521 ttagtcccaa ttctatattc atacatgcat acaaaaatat ttataaaaag tgtaataatt
     2581 aaagcaatta aactttctat agttatagca ggtacaactg gattagctat tcttaacact
     2641 gcactaagaa ttatcttaat tgctataaca aacaacatac cacttataaa taaactggtt
     2701 ataatttcaa actttttatg tccataagga tgatttttat cttttggttt agatgcaaag
     2761 aaaataccta taagccccac tatattagat gctccatctg acaaagaatg aaatccgtct
     2821 gctgtcatac tatagctttt tatttgatta ccaataatga tttttaataa tgctactgca
     2881 aaattagcaa ataaaattat ccacaatact tgcttcactt tcttatagtt atccataaca
     2941 aattccccct cccttcgatt caataaagaa agctatctat caatatcaat caaccagaca
     3001 ataaaatcgt atataagcac atttactata tttatattca aaattggttg tacttgttca
     3061 ttctatttga aacttaatta taaataaaaa tcgtaggtat ggttttggta tacataaaaa
     3121 taagagactg tctcaaaata aagataatct tcttttttat tgttgaaatg ataaaatata
     3181 tttgatttca tataaaaaag agtgcctcat gaactaaaaa gttcattttg agacactccc
     3241 ttaaattttt gatataaact attaattttt tatactaagc cttctttaac taagaatgaa
     3301 tgagcaactt cttctggtga tttaccaagt tcatccactt gatagttaag ttctctcata
     3361 gtttcttcat ttatttttcc tgaaagcata ttcataactt tttctaactc aggatatttc
     3421 ttcaaagtat cttctcttac taatggtgct gcataatatg gtacaaagaa atttttatcg
     3481 tcctctaata tcttaagatt aaacttttta ataagaccat cagttaaaaa tgcatctata
     3541 acctgagatt cattattatc taaagctgta tatcttaaac ttccattcat tgcttttaca
     3601 tctttgaatt ttaaaccata atctctagaa agtcctacaa gaccatcttc tctattttca
     3661 aactccaaag ttggtgagaa tgtaaattct ttaccatatt tagtcaaatc agaaatagta
     3721 tttattccat acttttcagc agtttcaggc atcatagcta atgtgtaagt attattaaat
     3781 ccaagagggt caagtaaagt taactgattt tctttttcca tagtatcttt tacaacatta
     3841 tatgcttcat cagcatcttt aatcggagca tgtttcatta catttaccaa aagtgtacct
     3901 gtatagtcaa catacatgtc taactcacca gatttaattg cattaaacgc aacagatgaa
     3961 ccacctagat ttaaattctt cttaacttta agattcgtat ttttttctac taattcagca
     4021 taaacattac caagtataag ttgttctgta taatctttag aaccaatagt tattgtatct
     4081 tttttacttg aaaaactaga actaaaaaca acgaacaaca ttgaaacaac aagcactaca
     4141 gatattactt taagtgctat atagttcttc ttaggtgctt ttggatttaa tccttttgga
     4201 gtaactgcaa cttcaatttt actaaataaa taatcaacta acagtgcaat tatacatgat
     4261 gggattgccc ctgctaaaat catattatta tttacagttt gaacccctga aaatactaaa
     4321 tatcctaaac caccagcacc tataaatgct gcaagagtca tcaaaccaac agctgtaact
     4381 gcagatattc taactccacc cattattata ggaagtgcta aagggaattg tattttaaat
     4441 aatgtctgat ttcttgtaag accaatacct ttagctgatt ctaatactac tgggtcaata
     4501 cttgttatac ctatatacgt attttttaca attggtagta atgaataaac cactaccata
     4561 aatatggctg gtttacttcc tataccaagt ataggtacaa gaagacccaa aagtgccata
     4621 gacggaactg cttggactaa gtttacaaat ccaagtacaa actttctaag agatgagatt
     4681 cttgaaataa ttattccaag aggaacacca actattatag ctattaaaat agatgtaaca
     4741 gttagactca tatgttgtat taaaagctct ataatcttat ctttttgtaa tagtataaag
     4801 ttaaaaaaat tagccaagaa cactcacctc catttctaag aattgttcac ttaaaacaga
     4861 aagtaaacta cttctagtaa taagccctac cagtttattt tcatcagaaa taaccggaat
     4921 atatccaacc gaattacgat tcattacatt tagtatttct actaaattat caccttcatt
     4981 tacatgcaaa ggctcacttg acataatatc agcaagtaat attgacttat catcaatatc
     5041 tttcatatct tttacagtaa caataccttt taatgttttt gctctatcta taattagtaa
     5101 gctatcaacc ttactcgttc tcataatttc tattccttga gttacagttc tagtagaatt
     5161 aacagcaata ggatttttta tcataatatc tcttgctttt atatattctg gattatccca
     5221 aactctatct tctccgataa aatcttttac aaagtcattt gcaggctttc taagtatatt
     5281 ttcgggagta tcatattgtg ctattcttcc atccttcata atacaaattt tatcagctat
     5341 ctttaaagcc tcatccatat catgagttac aaatattata gtttttttca attcatcttg
     5401 aagagaaaat aattgttctt gtaaagatgt tctcgttatt gggtctaaag cactaaaagg
     5461 ctcatccatc aatattattt cagcatcagt agcaatggct cttgcaacac cgattctttg
     5521 ttgctgtcca ccactaagtt ctgaaggata cttattcaaa aattcatcac tatcaagtcc
     5581 taccatctca agtagttgca acgttctttt ttcaatttct tcaacggatt tttccttttt
     5641 taggcgtgga attagctcta tattttcttt tattgtaaga tgagggaata ggcctgtgtt
     5701 ctgtataaca tatcctattt ttcttctaag ctctatttca ttttcctgag aaattggttt
     5761 gccattaata tatatctcac cagatgtagg ttttattaat ttgtttataa gcttcaaagt
     5821 agtagtcttt ccacaaccac ttgaaccaat caaaactacc aatgtacctg tttctacaac
     5881 tagagaaata tcatctaata taacattatt tcctattttt tttgttacat ttcttatctc
     5941 tatcataatt tatcatcccc tttttcgaac aagcaacctt cttcaatatt ataagttgtt
     6001 tttataatta tatcatacta ttttatttat gcaaacaaag tacgattttt aggtcactat
     6061 ttgtctgaat attgctacaa atataaagta tttatatata gtatataata tataatgtca
     6121 aaaaacaaaa aatataaaaa tattcataaa ataacactag cctcaattat atagtattaa
     6181 agctagtgtt atttcattta aacaaaactc acatttggat actatccatg tattcaaata
     6241 atgtaatatc tttataagtt tcttttttat cacttaggtt tgatattgta actcccaata
     6301 gcctaatttg ttttccatta acctcaacat ttctcaacaa attatctaca ccacttctta
     6361 tatcattata ttcgtcaata tagtgttcta aactaaggct tctagttatc tttgtaaagt
     6421 cctcatattt aatttttaat gttaatgttt ttccaaactt ctcagagttt tttaatctat
     6481 gacatacttc ttcacaaagt tcatcaagaa tgttgcgtgt ttcttcttca tcaatatcca
     6541 aattatgact taatgtagtc tcagccccaa cagattttct aaccctattt ggttccactg
     6601 gtctatcatc tattcctcta gcaaatttat ataattcata acctcttttt ttgaatatat
     6661 tttcaagttc aaataaattt aaacacctta aatcatatcc agtttttata cctaaatttt
     6721 taagagtatt tgaagtaact tttccaacac caaaaaattt attcacaggt aatttatcta
     6781 aaaagtcctg ggcattttct tcggttatta cagttaaccc atttggcttt cttaagtctg
     6841 atgcaatctt agcaagaaac ttattgtatg acacaccagc tgaagaagta agaccaactt
     6901 ctctaaatat atcttttttt atttgctttg ctatctcaat tgatgaatca atattttttt
     6961 tattttttgt tacatctaag taagcttcat ctaaagataa tggttcaact aaatccgtgt
     7021 atctataaaa tatatctctt atttgctctg acacactctt ataaacatca aatctaggtc
     7081 ttacaaaaac tgcatatgga cacctattgt aagctacagc tgatggcata gctgaatgga
     7141 taccaaattt tctagcttca taagaacatg ttgcaaccac acctcggctt tgtggatttc
     7201 caccgacaat aacaggtctt ccttttaatt ttttattatc tctttgttct atagatgcat
     7261 aaaaagcgtc catatctata tgaattattt ttctataatg tttcattatt atcacctttt
     7321 aaagtataaa tagattaatt ttatttatat tactttttaa ttataccaaa cttatgtttc
     7381 tttttggtat tttttcatta ttttctttat atattcatat tttccataaa taaaaccatc
     7441 tataatccat taacttcaat ataatttata aaaaatcctt aaaaacactt gcaaaaacta
     7501 tataaaagct ttacaatagg tattccaagg aactaaattt aaaattcctt atggataaca
     7561 gtatatatat ttaatttatg ggatgtttta aaaacaaaag actgtcttat acaagacagc
     7621 ctactgattt tattataatt gtaatggact gctcaaacta ttactttaaa acagcccata
     7681 tttttttata taattttaac tatagtaaag attttgtgaa ggatattctg ggtcacaagt
     7741 tacatctata ccaagttttc taaatgtttg ttcatcatct ctatttaata tagtagtaga
     7801 atgagcttga caccctttta ataatgctaa cttttccata gcaaattgtg cagttggatt
     7861 agttacagca caaatactaa gtgcagttaa cacctcttgg caactaagtg aaacatttct
     7921 actagctaaa gtctttgttt ttaagtttat gataggttct aatattacag gtgatattaa
     7981 gtgcatatca tcagatatat tggctaaatg tttaatggca tttaatacta ctgctgcagt
     8041 tccattcatt aaatcagaac ccttaccagt taatattgta ccatcttcta attctaatgc
     8101 aactacagga caagtatcat tcttgtcggc actttctttc aatttattac tgtagtttct
     8161 agcaggtaat acaacatttc tatcttctgg ctttaagtta agctcttcca taatcatttt
     8221 cattctatca taagcacctt tatcaacttg tcccttttta tactcacagg cagttttaaa
     8281 gtatcttctt attatttctt ctatagaagc ttttcttatt acttcatcat ctattattcc
     8341 aaagccaact ctattaacac ccatatcagt tggagattgg aaaattgatt cttttccagt
     8401 tatcttttct attatttttt taagcactgg aaataattcc aaatctctat tgtagtttac
     8461 tgacatttca ccatacgttt caaggtggaa tgaatctatc atattcacat cttttaaatc
     8521 aactgtagct gcttcataag ctatattcaa aggatgtttt acaggtacat tccaaactgg
     8581 gaatgtctca aacttagaat atccaactac attacctctt ttattttcat gatacaactg
     8641 acttagacaa gtaccaagtt ttccactatt aggtcctggt gctgtgacta ctactattgg
     8701 ctttgtagtt tctatatatt catttgctcc atatccctca tcactaacta tagtctcaac
     8761 atctgacgga tatccctttg ttggataatg cttataaact ttaattcctc tacgttctaa
     8821 tttatttata aatacagttg tagcaggttg tccttcaaat ctagtaatta ctacactatt
     8881 tacatctagt tcataacctc ttaaatcatc tattaatctt aaaacttcca tatcataagt
     8941 gataccaaag tctcctctta ttttgtttct ttctatatct cctgcataga cacaaattac
     9001 aacttcaact ttttctttca tatgttgtaa tacttttatc tttgcatttt catcaaatcc
     9061 tggaagtact ctttttgcat gaaggtctcc catcaatttt cctccaaact ctaaataaag
     9121 tttgtcaaaa ttatttactc tttctaagat atatttagac tgctcttcta aatatttttt
     9181 gtggtcaaat cctactttca tcttaacacc tcactaaatt aaatttcttg ttgataacag
     9241 tatatttata tatatttttt tagtaaaaca tcttataaaa aaatgttaat actttttcac
     9301 tcaaagtaat attatacaat taagattaat ttttttcaag atagttttat ggtaaataag
     9361 atatacctat ataactaata aaataagaat actatatttt tatatataag tataatattc
     9421 tcaccttagc attaatttat ttcaatattt tcatatatct tttattctaa attcaatact
     9481 tttctaatat cttctatacc ttgataaact tcttgtttag aaaaattcat agcttctaat
     9541 tcttcatcag tcttttccat aagcatagta taaaattcta ttgctatata ctgcatattt
     9601 tcactattta cactcttagc tttatcaaat aaaatttctt ctgcttcgtt tacatttccc
     9661 tgaaaaacta atctttttaa agttataagt ataacttctt cttctgtatt atacactaaa
     9721 tctttttctt catattcact gtattttttt cccaataaaa gtcttgcaac cataagtttt
     9781 atctcattga aaatcttatc cactatagcc atttttacat ctcctataaa taaattttat
     9841 tttcttttta attatatcag actttatcgt aaaaattatt atatgtaaat gaaataattc
     9901 aaaaataaat tttaacaata aaaaaaagaa ggtagcgggg gatttccgac taccttcaaa
     9961 cactagattg tgattggttt ggtattttat ttatacccac cataagcttt attaaatcat
    10021 ctaaattgat ttttttagca tccacatcct ccatcaaaaa cgtcaccaca ttcacaaagt
    10081 attaataata atattaagaa aggtatccat gcacataagt ccatttcagc ccaacaatct
    10141 tggaatgcta agaataagaa gaataatatt attatccacc aagcacatcc accaaatccg
    10201 ccttcaccaa aaaatctatc caacataata tgttacctcc tagtcatttt gtatgtggag
    10261 tttcagctcc taaaatatac tatgtttaag gggtaatatt tgctaatgat ttttttaaat
    10321 ttttttagat atttttaaaa aaattattga ttcacactca atgtcttacc atcactattg
    10381 ataactacct ctccattaga agtcaaaaat gtttttatat tcaatctttc caatattttt
    10441 aaaacacctt cctctggttc ttttttctct gaacatgtaa taacagcata ttgaggtgaa
    10501 atagactcta aaaatgtttc agttaatttg tcatatcttc catgatgagg cattttaaca
    10561 aaatcatatt ttaaagtatt tccatttata aactctgaca atctttcttc ctctgcatct
    10621 cctgcaaata aaaacttatg tgctccatag cttatattag tgattattga ataatcattt
    10681 gaactctcgt acttgctttt tgaagccgga tgtatgttta tttctgcacc attgattaca
    10741 atattcatat tatcttttag tagcactggt tctatatcag cttttttaag tgagtcaata
    10801 tattcatcat attgcttact atctttctta taatttgctt gtataatatt ctttacttta
    10861 acactagata acacactatc tactccacct atatggtcct tatctaaatg agttaaaatc
    10921 aaatagtcaa gtgtatttat tcctttttct tttaacctat ccactatttg ttttccattt
    10981 ttatcttctc ctgtatcaat cattatgact ttgttaccta tctcaaccaa tatgcaatca
    11041 gactttccag tgtttagtat agtagtctta aatgcagtat tttttgtgct actctttgtg
    11101 ctcctctgga taccattttg cctcacacta tttttgtcac tttttaaata agattcactt
    11161 gttgatttta tcttactatt agtagttata tttgttacaa gcaataatat tactattata
    11221 gataatgtag taactaaaaa caggatatct tttaatacta ttttcctcat ccaaaagctc
    11281 ctataaattt tatttattac atatttatag tatagcaacc ttaactctgt aaaatacaca
    11341 tataaaaagg gcaaatttta ggcatatttg tggcataata aaaaaatgac tgtaccaaaa
    11401 caattatctt tctaaattta catcttcaaa ttctttaatc ttatcattag ataaaacact
    11461 ctttttagta gattgtccat tttttctatc aaaagtattt ttggctttta cacctgataa
    11521 aaacttaccg gctccattaa tacaaccttc ttcacacatc attccttcta taaaattacc
    11581 ttctaatctt cccaatttag ccattgtcat tgtcttttta atttgtcttg gaccagatac
    11641 ttttataggt tcaaaatcaa aactaagccc cttttcagca atatagttct gtactgattt
    11701 ggcaagtcca ccagatgctc caaatcccct tccaaaaatc gaaccatcat ttatatcttc
    11761 atttgaacat tttgataaat ctatattaaa tgcttcaaat aatgccatta gttcttcaaa
    11821 agtaagtaca taatctactg aatcttttaa acttttctct gttgcctcac tctttttagc
    11881 tgtacatgga cctataaata caactttagc atcagaatct atttttttta ctaatcttcc
    11941 tgttgctacc ataggagaca ctgtagatga tattctatct ttttcatctg ggaacatctt
    12001 ctctatatac ttaaaaaatc ccggacaaca tgaatttgtc atgtaattat ctcctgattt
    12061 tattctttca ataagttcat tgctttcatg aactgtaact gcatctgctc cacaagaagc
    12121 ttctatcata tctacaaatc ccagtgattt tatagcattt tttaactgac catatgtaat
    12181 attactatct atttgacctg ttatagctgg agctactatt gcatacatat tttctttctt
    12241 tgcaagtttt tttgcaacag gtgctatcaa actcttatca gatattgctc caaaaggaca
    12301 tgctgacata catgctccac aatttataca attatcttca tgtatcattg ctttcatagt
    12361 gtttctatta aaatccaaag ctcctgttgg acaaacgctt ttacaaggtc ttacaacttc
    12421 tgatatagca tcatattgac atgaactttt gcacattcca caagccttac ataaatcatg
    12481 atttatatat gctctcccat ttatataaga aattgcccca aatttacatg cttccttaca
    12541 tctatgagcc aaacaccctc tacaaagctc tgtaactgta aattcattta ttggacatct
    12601 atcacatgct gcttcaacta tatatataat ttgctcatct gtgtccaaac taactgaatc
    12661 tggatttata tctccatatt tactatttgg agttaaactt aatgcaagtt gcgccctttc
    12721 aagaactact tctctctctt tataaacaca acatctatat ctcgcctttt ctcctttaat
    12781 tatttcatat ggaatttttt ctatattttc ttttgttaaa ttttcttcaa tagatagtct
    12841 tgctactgct gttaaaactt catgttttaa cctttttagt tgcgtttcaa attcaaacat
    12901 aagtaatcct ccctataaat cacacctttt tgctatattt ctactattat gtatattgta
    12961 ttttttattt atttctataa attattataa cataggcata tactttgtta agttatatac
    13021 aaaatattat atatgtaatt tttattttaa gtgtatataa tttttatttt agttgttcaa
    13081 taattaaata tataaataaa aatagagttg tccaaaagtt aaacctcaac ttagaacaac
    13141 tctattaaca atatgtattt ttgttgcttt gtattatctt tatttttcta aatttatatt
    13201 actaaaatct tttatctttg tatttgctaa gacacttttc ttagttgatt gagaattttt
    13261 tctatcaaaa gtggctttaa cctttgcacc tgataagaat ttaccagaac catttataca
    13321 accaccttca cacatcattc cttctataaa attaccttct agctttccta aattagccat
    13381 agtcatagtt ttcttgattt ctcttgaacc agaaatcttt acaggttcaa aattaacacc
    13441 aatacctttt tcagcaagat aattttctat agcttttgta agaccaccag cagctccaaa
    13501 acctcttcca aaaattgatg catcatctat atcttcattt gaacacttag ccaagtctat
    13561 atcaaatgcc tcaaataatg ccattatttc ttcaaaagta agtacataat caacagctcc
    13621 ttttaattct ttcttagctg cctcactctt tttggctgta catggtccta tgaatacaac
    13681 tttagcatct ggttcatgac tttttataaa tctaccacta gctatcatag gagatactgt
    13741 agaagatatt ttccctacat gatttgggta tgttttttct atataaccaa caaatcctgg
    13801 acaacaagaa tttgtcataa aagcttctcc cttttccatt ctttcagcaa attctaagct
    13861 ttcatgaact gtaactgcat ctgctccaca agctgcttct aatacatcaa caaatcctag
    13921 tgattttata gcatttttta tttgaccata tgtaacattt gcttcaactt gacctgttat
    13981 agctggagct accaccgcat acattttctc tttttgaact aactttctag ctacaggagc
    14041 tatcaaactc ttatcagata ttgctccaaa tggacatgct gacatacatg ctccacagtt
    14101 taaacattta tcctcatgta tcatagcttt catattttct ctatcaaatc ctaaggcatt
    14161 agttggacaa acactcttac atggtctaac aacctctgag atggcatcat attgacaagc
    14221 ttttttacac attccacaag ccttacataa ttcatgattt atataggcca ttcctccgac
    14281 atgtgttata gctccaaatt tacaagcttc tttacatcta tgtgctagac atcctctaca
    14341 aatatctgtt actgtaaatt catttattgg acaactgtca catgcagctt ccaaaatata
    14401 tataatttgt tcatcttctt ctatatccat tgtatctaaa tctatcttat cttgacctgg
    14461 ttgtaacccc atacttacat ttactctctc agatattata gctctttctt tataaacaca
    14521 acatctgtat gtaggtttct caccttttat tatttcatac tgaatattat ccattgcttc
    14581 tctggtaagg ttatcttctt ttccaagtct agctattgca gttaaaacat catgtcttaa
    14641 tttgtgtatt tgtgtttcaa attgaaacat tttaatacca cccccgtaaa tgattttata
    14701 cgataccatt ataacacaat atgtcctttt attaatatat acataaaata ttatatgttt
    14761 aaattttatt ttatcgaata tatatagtgt ttttttgttt tattatataa tattattgat
    14821 atttctgaaa tttcactatt tttattttta cttttcaatc taatatataa tattttttat
    14881 tatatatttt aattttactt tttacttaca tacctttttg ttacattttt tgatattaaa
    14941 tttattatct acatttacat tttcgtcaaa ttttacaata cttctcactg tataatttaa
    15001 caatttttat taaattctaa aagtaattaa tttttttaaa aattttattt gcttttattt
    15061 aaaatttatg ttatattaat agaacagact tattttttta gtttgtattt tttaataatg
    15121 cggaggtttt cttataatga aaaacggaat agtaaaatgg tttaacaatg aaaaaggatt
    15181 tgggttcata tctgtagagg gagaagatga tgttttcgta catttctcag ctatacaaaa
    15241 tgatggatac aaaactttag aagaaggcga aaaggttagc tttgatataa ctcaaggtaa
    15301 tagaggacct caagctgaaa acgtaaatag aatataatta tttaatttaa atatatatat
    15361 tttagaaaag gagctatcga gggctctttt ttgttgttta ttatatttat ttttaattac
    15421 aaaaataaga agttacttta gaaaagcgtc aaacttaaac taactttttt aaaataactt
    15481 cttatattat aatatatact atttatataa aatactctat ttaattttat cagatattat
    15541 taagcataac tctcttaaga ttttacaagc tataactgtc gatacacctg ttgtatcgta
    15601 atcagggctt aactctacaa tgtcacaacc aactatattt atattagagt tttttataat
    15661 cttaaaaatc tcttgaaact ctctataatt tacaccacca ggttctggtg tacctgttcc
    15721 tggaaacaca gatgcatcca atacatctaa atctatagtt agataaatat tctttccatt
    15781 tagcatatta actatatttt caaacgtatc tattcctcct atttccatgt atgtgtgttt
    15841 ttcttctgta gcaaatttaa attcttcttt tgtcccagac cttataccaa attgaaatat
    15901 tttattatca cctacaatat cccatattct tttaattact gttgcatgag aatttttact
    15961 attattatat tcttccctca aatcagtatg ggcatcaaaa tgaattacat atatatcatt
    16021 gtacttttca tgtactgctt taaaggctgg taatgtaact aaatgctctc ctccaatcat
    16081 aaagggtacc tttgaatctc taacaatctt atatgtctct tgatagattt cttttaagac
    16141 ttgttctgta cttccaacac taatttctaa atctccataa tcacatatat tataatcctc
    16201 taaatccaaa tctaaaaaag gactatatgt ctcaagaccg taaaattctt ttctcataga
    16261 gctacttgca aatctagccc caggtctgtt agaagtagtt ccatcaaatc caacaccaaa
    16321 tactataaga ttagattctt cataattttt gtccatactc ataaaagtgt tcatatgata
    16381 gaaattattc ttcatctagc atctccttca cgtattgagg taacataaac gaacctaaat
    16441 gtatatcact attataatat ttagttttta aacttaattt ctcccatcca tttctatctt
    16501 gattttttac tggattaagt ttttttgaag caaatccaaa caaccagtga ccagatggat
    16561 atgttggtat atgtgcttga taaacttctg atattggaaa tatctgtttt aattttttat
    16621 tagctctttt catctcttta gcattaaagt caaaatacgg actttcactt tgatttacta
    16681 aaattccatc atcagtcagt attctataac aatccttata aaaatcagtt gagaaaagcc
    16741 cttcacctgg tcctattggg tcagttgaat ctactattat caggtcatat gatttatcat
    16801 gtgcacactt aacaaaatta acaccatctt caaaatataa actcactctt ttatcatcta
    16861 atttacatga gcatatatcc atatactcct tagatacatc tacaaccatt ttatctattt
    16921 caaccatgtc aatcttttct atttgaggat aacggcttaa ttctcttact gtacctccat
    16981 cacctccacc tatgactaat actttcttta tgtttaaatt tgtagccata ggaacatgag
    17041 ttatcatctc atggtatata aattcatctt tatatgttac catcattaat ccatctattg
    17101 ttagaaattt tccaaattca tcactatcaa acacatctat cctttgaaat tgagactttc
    17161 cttcaaatag atgtttattt acttttatag aaaatcttac attttctgtc cattcttctg
    17221 tataccaaag ttccatataa taatcctcac tttctcttgt atgttttata ctgcttctgg
    17281 tttatgagta atcttaccta aatctttttt tgaatatttt ttaatttttg tagttaagcc
    17341 tcttggaatt tctgtagact cgcttctttc agactttaaa agttgctcta ataattcaaa
    17401 acttttccat gggtctatat caccacaagt aaaaaaatct gctgctgcat agccatattc
    17461 aggccatgta tgtattgtca aatgagattc agcaattata acagctcctg aaacccccca
    17521 aggattaaaa tggtggaata cagaatccac aattgtcgct tttgcattta atgctgaatc
    17581 attcataaaa ttttctataa gacgtgggtc tttaagtacg ttttcatcac aattatagta
    17641 ttctactagt atatgtcttc ctagtgtttc aaatttcatt tcaaccccaa ctcctttata
    17701 cttttaataa gttctatttg ataaactcta cttaacaaat acttgccctt gcaaaataaa
    17761 gtaatttatt ttattactaa tattctatct aagtttttat cttgtacatc tgtaagatat
    17821 gcattgctat tttttaagaa aataatatac tccataattt cttctgttat caattctcct
    17881 ggagcaataa tcggtatacc tggtggatat gccattattg attctccaca aattctatct
    17941 atacatgaat tgatttctac actttccttt ggtgcataaa aagcttctct tggattaagt
    18001 ttaataattg gatttatttg aaccatatta aattcattta atgttgattc ttttctataa
    18061 atctttgcaa ttatagaaag tgcttttact aatctatcta tatctgattt atttgttcca
    18121 atggacacaa gtgccagtat attatatgaa tctcccaatt ctacttgaat tgaaaaattt
    18181 ttatataata aatcgtatac ttcaaatcca gtcaaattta attcttttac atttatacac
    18241 aattttgttt catctataaa tttaacacct ttttgtttca atatttctgt agataaaact
    18301 tttattccat caattttgtt taatttagat tttgcatacc tagatagatt taatgctttt
    18361 gacagttgct tttcaccatt ctcaactaga ttaactctag caccatctat acttgccata
    18421 agcaaataag atgctgatgt tgattgtagc atattgattg attgaagaac cttttcaaaa
    18481 cttacattat ctctattcaa taagagtgct gaagattgtg tcaatgctcc tccagtttta
    18541 tgtatactta cagctaccat atcagctcca aaacttattg cagaaggagg taaatctaaa
    18601 tgaaatggaa aatgtgcacc atgagcttca tcaactaaca ctaaaacatt atttttatgg
    18661 catagttcta taatactctc aaggtctgca caaactccat agtaagttgg attaaggaaa
    18721 aataatgctt ttatattaca atctttttct atctctgttc taactttttc aagagtaata
    18781 tttaaactta tacctagttt ttcatcaaat tctggttgta taaatattgg tattcctcca
    18841 caaagtatta acgcatttat tactgattta tgtatatttc ttggaagtaa tactttttca
    18901 cctggtttta taacactcaa aatcattgca tgtattgctt gagttgtgcc attcgttata
    18961 aagaatgcct catcagccat atatgcttgt gctagcaaat cttgtgcatt ttttataatc
    19021 ccatttggcg cagatacatt atccatagtt ggtgatgaat ttatatccat tttcatgaga
    19081 ctttcaccta gatatttatt taatatagct acacctctat tttttacatg tccaggcaca
    19141 tcaaaacaag ctatatcttt ctctgagtat tcctttaacg actctaataa tggagcacac
    19201 tcatagctta attcaactgc atttgcaaac tcgctatcca tgatttcaaa ttcatctcct
    19261 ctctatattc aaatattttt aatatttatt atttattatt tctatttttt atttttactt
    19321 ttattaaact catgatattt attatattaa catcccagca tttttacaag tgtttttttg
    19381 aagttactca aaaacatata cattagctat atcaatattt ataaactttt taattttttg
    19441 ttgtttatat taattttttt aaaacttagt atttataaac tttcttattt tttattattt
    19501 tggttttttt acttttttga gttttagtaa gcttttgagt ttactatttt taatttataa
    19561 gtattttatt actaaacttt tatattattc ttatttcaca tatcaaaatt cttggtttag
    19621 ttggactaaa taattttcct atttttgtat tttaatttta atataaaatt tattaaattt
    19681 tttaattgat aaaataaatt ctatatttat gatattaaaa ttctataagt tcattgattt
    19741 atatatgtta atttaaatac attattctat cgtagtgcct tagagttttt atttgtattt
    19801 aaagttaaat ttattcttgt ttttccttta atatttaata gtaaaacaac aaaattataa
    19861 aaaaaataaa gagaaacttt ataaaagctt ctcttttttc atctctgcta taggtatcgt
    19921 tttccaatgt tctctcaaaa ctctttcaac attttctaaa tcattctccc tcatagattt
    19981 tactacttca atatgttgat tattgctgta tgtcaacatt ttatataact catcttcatt
    20041 atcactagta tatgactttg acataaaatt atatcttaaa gagttcaata gatttactaa
    20101 cacctgatta tctgatttag ttatgtatat atcgtgaaat tcattactta attttaaata
    20161 gctattgtaa tttttatact ttatagagac cgccatcatt tctgttaatt cttccatttt
    20221 tactaggtct gattcagtta aattttgtaa tgctgaagaa ccggctaacg catccaatac
    20281 tccaattacg gaataggtgt ctaatttctc cttttcctga aattctttta ctacaaatcc
    20341 cttattaggt attttttcta gtaaattttc acctgctaac ctagttaatg cttctctcgc
    20401 tggtgttcta ctaactccga tagatttaca aatctcagat tcagtaattc tctgattagc
    20461 ttcatattct ccattttgga ttttctttga tatatagtca tatacttgag ttgtaagtgg
    20521 atctaccttc ataagacgtt cctccatatt aagattataa aagttaaatc tccctacaac
    20581 tttggtagag agttcagttt tatcttacta atttatataa tatcacaatt atgatatttt
    20641 ttatacttct ttgtaatatt ttgaaatact aaaattctta tgataattta tacaaaaaaa
    20701 gtagaaaaag ttttgataaa acaaaactct ttccacattc accttatttt ctatttattt
    20761 ttctaaaaaa agatatttaa tttactctaa aaattctaaa tgatttagag tctaaatcta
    20821 ctttcaactc attattttca atttgtatag tactatttgc atttttaaga ctatacttta
    20881 taggtatttc ctcaataaaa ctactctcta tacataatga tatactttcc acattttcac
    20941 ttctatttac taaaattaac attctatcat tattttcatt aactctaata aaagaaaata
    21001 cagaatcatt attagtatat ataaattctg tatttccaga acttaaaagt ttattcttat
    21061 ttctaatttt tataacatct ctataaaaat taagcatatc ttcgtcttca tttttccatg
    21121 gataagttct tctattatct gggtcaacac ctccacaaag acctgcttca tctccataat
    21181 atatatatgg tactccttca aatgtcatct gtatagctac agcaagcttc actaaatcta
    21241 catcatcatt taattccgtt ttagctcttg taacatcatg tgttccaatt aaatttaaat
    21301 tagacctaaa tgattctttt ggataatttt ctttaatctg catatatcta ttacaaagtt
    21361 catatgaatt aatttctcct tttaagaaag aaaacatgtt atttctaaaa ggataaccca
    21421 taacagaatc taattcttca cctaataaat aacttcttct ctgaccatag ctaatcttat
    21481 ttgatgcatc ttcccatact tcacctataa gaattgagtc atcatctgca ttttttaatt
    21541 ccttttttaa ctctcttata aacttagttg gtaattcgtc tgcaacatct agtctccagc
    21601 ccttaatacc catatttacc catttattta taacgctatc attgtcatat attatataat
    21661 ccatatagct atgttctaat tcatttatat ttggcaatgt cttaacatcc caccaacttt
    21721 tatatttttg aggaaattct tcaaacatat accatgaata atatggagat tctttagatt
    21781 gatatgcccc taaactatta tagtttccat acatattaaa atatttacta tctgctccag
    21841 tatgactaaa aactccatct aatactattg atataccttt ttcttttgct ttatcaataa
    21901 gttctttaaa tgtatcttca tctccaaaca ttgggtcaat ttttttatag tcacctgtat
    21961 catacttatg attactagag gcttcaaata tagggcttag atatagtata cttacaccta
    22021 atttttttaa atatccaagt ttattgatta tccctcttaa atttccacca tggaaatccc
    22081 atcttataac atccccttga ctatccttta tgtacatagg tgtatcttcc caatttccat
    22141 atatgaaact atttttttta ggattatcaa ccttaccact acgatttcca ttattgaatc
    22201 tatctacaaa tatatgataa agtattcctt ctttgtacca tgttggtact ttaaaatctt
    22261 tataaacagt gatttgatat ttattaatat cactataatt atattcacaa gaatatccat
    22321 tatctctgtt ttttccataa aataaagtct ttatttgacc atccatttca acatcaactt
    22381 taaagtaata aaaataaaca cctgtaccat caaacttttc aatcttacca caaaagcact
    22441 ttccaagttt atcattatct aattcttcat ttaaagttat tgttctcatt tcttcttctc
    22501 tatttatttc tagggaaata gacttgatat tgtatccctc atttacttta acacaaatgg
    22561 tcaattcctc atcaaatttt aaagctccaa acggagcctt aaaattttta tcccaagagt
    22621 tatattctat tacactttgc atttaatcac acccttttaa accaaatgtc ttttgcatac
    22681 tcagaaattg ttctatcaga agaaaaaaat ccagagttag ctatattaac taaagacatt
    22741 ttattccatt tttctttatc tctatataac ctgtttatat ctgcttgagc ttgaccataa
    22801 ttttcaaaat ctctcaatac aaaatactca tcattgtaag tagtgagtga attataaata
    22861 cttcttcctt cttcgccaag attaggaata aatccattta ttaaatcatc tactaccctt
    22921 tttatatcca tattagaatg atataggtca agtgaagaat atccaccata tttattataa
    22981 tttagtactt gttctgcact aagtccaaat aaaaacatat tttctttacc aacctgttca
    23041 catatctcta catttgcacc gtcaagtgta gccaaagtta tagcaccatt catcataaac
    23101 ttcatattac ttgttccaga tgcttcctta gttgtagttg aaatttgctc actaacattt
    23161 gctgctggta ttattatttc tgctaatgat actccataat tctctaaaaa tactactttt
    23221 aacttgtcct ttactctaac atcattattt atagtacttg caacagaatt tataaattta
    23281 attatacatt tagccaaata atatcctggt gctgcttttg cgccaaatat aaaagttctt
    23341 gggtcaagat tcaaattagg attatcaagt aattcatgat acatatgaag tacattaaat
    23401 atattcagta actgtctttt atacgcatgc aatctcttaa cttgaacatc aaatatcgaa
    23461 cttgggtcta catttaaatc gtatttatct tttataaact ttgctagatt tgctttatta
    23521 ttgtatttta tatcatcaag tctttgtaaa acagaggaat catttttaaa tttttcaata
    23581 ttttttaatt gtaatgtatc tttcttccat gaatcaccaa ttaaatctgt aattaaattg
    23641 ctaagttgag gatttgaact tataagccat cgcctatgtg caattccatt agtcttatta
    23701 ttaaatttat ttggttcatc ttgatagaaa tcttttaata cctctgtttc aagaatatga
    23761 gtatgaagct tagcaactcc atttacacta tgacttgtga caatacataa gtttgccata
    23821 ttgatattgt cacagtctat tatactcatt ctttttattc tatcttggtc atatccttta
    23881 ttatttaatt cctctacata tcttctattt atttcttcta ttatcatata aattcttggt
    23941 aatagctctt tcatcatact tacaggccat ttttccattg cttctgacat tatagtatga
    24001 ttagtatagg acactgtttt tttagttatt tcccatgctt catcccaaga taaattttct
    24061 tcatcaagca aaattctcat aagttctggt atgcataagg taggatgtgt atcatttata
    24121 tgaattgcta ccttatcgaa taaattatta atatttaatt tgttcttttt atattttctt
    24181 attatatctt gtatccctgc acttacaaaa aagtattctt gtttcaacct caacaactta
    24241 cctgcataat ttgaatcatc aggatataat acctgtgata tttcctcagt ataatactta
    24301 tgttttaaag cctcttcata gctaccagaa taatttagag catttgaggt aagttcacca
    24361 aaatctctct ttggtatttc actcttaaac aatcttaaag tatttataca ttggttttgg
    24421 tatccgatta ttggtatatc ataaggcatt gccattacag gaaggtagtt tttatgaatt
    24481 acttttaaat gactaccttc cttgattaat tctacctcac caccaaactt caccattgtt
    24541 gcttcatttg gtcttacagt ttcccatgca tatcgtcctt ctgtaagcca gttatcaggc
    24601 acttctacct gataaccatt tacaaatttt tgttcaaaca gaccatattt ataccttatt
    24661 ccatatcctt gaccacttat gttcaaagat gccatagaat ctaaaaagca agctgctaat
    24721 ctaccaagtc caccatttcc taaggctggg tctacttcag cttcaattaa atcatccaag
    24781 ttgattccta attcagataa accttctcta acttcttctt caatatttaa atttaataaa
    24841 ttagatttta actgtctccc tattaaaaat tctaaactaa aataataaac ttcttttttc
    24901 ttatctaact ttgtagcaac ccattttttt gctatctcat ctttcaatag actacataat
    24961 acatttaaca attgttcatc agtagcttcc ttgatagatt gtgcatataa gctatacatt
    25021 tttacttcaa atttttgctt gaatttcttt ttgcttattg ttaccaaaaa aaccactcct
    25081 ttaatcacat atgtctctat atgtttctat atactcctta gctgattttt tccaactatt
    25141 atctgttttc attgcatttt caactaattt aatccatttt tctttgtcct taaatacttt
    25201 gattgcattt ttcaaacaga aaaacatctc atgagcattg taatttttaa aactaaatcc
    25261 attgccttct ccagtaaatt tattataagg tgttactgta tctctaagcc ctccagtctc
    25321 tctaactatt ggtaaagaac catatctcat agctaacatt tgacctatac cacaaggctc
    25381 aaataatgat ggcattaaga acatatcact tgcagcatat atctgttgag ccaatgatgc
    25441 attaaaagta attctagctg atactttatc tgaaaaatta gaatcgtaat agttgaacat
    25501 tgattgatat tgatgttctc cagttcctaa aacgacaatc tgtaaatctt ctctcataag
    25561 ttctggcatc atgtatgcta ttaaatcaaa tcctttttga gaaactaatc tcgaaactat
    25621 acctatcaac ggaatagatg aatctttttt tagtcccaat atatcttgta atctcaattt
    25681 attttctact tttttgttaa ttgagtctac atcataatga acaaatatat ctttatcttt
    25741 tgcagggtca tttaaatcat aatctatacc atttaatata ccttttaatt ttcctgactc
    25801 ttttctaagt aatccatcta attgttcgcc ataaaaagat gtttgtattt catttgcata
    25861 agtaggacta acagttataa ttttatctgc aaaatttata ccagctttca taaaatttat
    25921 tgagccataa tactctatat ctccattatc aaagtatttt tgtggtaaat ccaatatatc
    25981 atataaaaca tgcttatcaa atacaccttg atattggaga ttatgtatag tatacatagt
    26041 ttttatattt ttatacccct caagggttgc atatctttct tttagaatta atggtaacat
    26101 ccctgtatgc caatcattta tatgtattac atctggataa aaatcaattc tacttatagc
    26161 ttctaaaact gcatctgtaa agaaagtata tctttctgca tcatctccat atccatagat
    26221 actctttctt tcatcttctc ttctaaaata aaattcatta tctataaagt aaaattttac
    26281 accatctaat tccatttcta aaagaccaca gtattgattt ctccatccaa cacgtacact
    26341 aaacacagct atttctttta gttgatcttt taaataactt ggtatagttg aatatttggg
    26401 cattattacc cttacatcta caccttcttt ttttaattct ttaggcaatg cataagaaac
    26461 atctcctaat cctccagttt ttgcaaaggg ccaacactct gctgttacat aaaaaacctt
    26521 cattagtcat tcccccttct aaaaaattta tttatatatt tgtattcttt tccactacaa
    26581 gaggatattt ttcatctcct cttaattctt tcccatttga tacactcgta tttttatcta
    26641 atattgcatt atatagtttt gcatttgact ttattacaca attttgcatt actattgagt
    26701 tctctataac tgttcctttt tcaacattta cctttctaaa tatgatacta tcttttacag
    26761 taccttctat taaacaacca gatgctataa agctattttc tactttagca ctatctgtat
    26821 aaattgtagg tgattcattc ttttcttttg taaatatctt tctttcagaa tataataatt
    26881 catctgcaac ttctaaattt aataaatctt tgctcatttc aaaatatgat tcaacagaat
    26941 ttacacattt tagatatcct gtatattcat aggctcctat tttcatgttt tctgcttctt
    27001 caataataaa ttcttctaaa taacaataat tgcctttatt tacaatgtta tatatacatt
    27061 caacaaaatc ttcacgcttc ataatatatg tctccataca tatgtttgct ctagggaact
    27121 tacctaaatt atttcctaca tttattaccc tattgttact atctaaattt agagttaagt
    27181 taccagcaaa atctttattt gcattattta catttttata tattatagtt atatcattat
    27241 gagatttttt atggtattcc aatgcttgag aataatttaa attgcatagc atatagcttg
    27301 gagctattaa aatatattct tcttcactct tttctatata atctagatta gctaagatag
    27361 tatatatatc accttctcta tgtgagtaag tatttctata cttagtgttt tctggactaa
    27421 aaattgatag gccacctttt tttctactta aatcccaatc tttaccacta cctatatggt
    27481 ctgttaatga tctgtatttt tcttttgcga atattccaac tttagtgatt cctgaattta
    27541 tcatattaga taaagcaaag tctattattc tatatcttcc agctattggt gtagatgcta
    27601 ttggtcttcc atagttaagt ttgtttattg ctgggtctcc ttttttgttt aaatttatta
    27661 tccctaaaca ttcatttctc atcttaaaga cctccttcta ttaatacgca tctaggttcg
    27721 atattttcat actcagaaac tacatttatt tcattattta cattctttat ctgaacatta
    27781 tcatttatag ttgcacactc acctatcata gctttttcta tagttacatt ttcacctatt
    27841 acaacatttg gcattattac tgaatcaatt actttacttc ctttaccaac aacaactcca
    27901 tgtgataata cagagttacc tacttcacct aaaattctac aaccatcagc tatcattgat
    27961 ctatgaacat ttgcattttt acctatatat tgtggaggca ttgccatagt atttgtatat
    28021 atcttccact tagggtctgc taaatcaagt gtttctggag attttattat atccatatta
    28081 gcatcccata gactttgtat agttcctaca tctctccagt atcctttaaa tggataagca
    28141 tacattccaa cattatcttc taacatttta ggtattaaat tttttccaaa atcatcataa
    28201 tttatttctg gatttttttc tgcttcctta aaataatttc tcaacatttt ccaatcaaat
    28261 atgtatactc ccatagatgc caaattgctc ttaggttcac ttggtttttc ttcaaattca
    28321 tagatacttg aatcttcatt tgtattcatt atcccaaatc ttgaagcttc atcccaagga
    28381 acttcaatca ctgctattgt agctttagag cctttttcct tatgaaattt taacattttg
    28441 ctataatcca tcttgtatat atggtcacca gataatatca atacatattc tggattatag
    28501 gtatctacaa agtccatatt ttgatatatc gcatgtgctg taccattata ccaatttcct
    28561 tctttttcat tcataaatgg ttgtaaaaca tagacaccac catttattct gtccaaatcc
    28621 caatgacttc ccatgcctat atgtgaattt aatatcaacg gtctatattg agttaaaaca
    28681 cctacagtat caataccaga gtttgaacaa ttgcttaaca caaaatctat aattctatac
    28741 ttacctccaa atgatacagc tggtttggca attctttttg taaaaacacc taatcttgaa
    28801 ccttgccctc ctgccaaaat catagctaac atctcttttt tcatttaatg acactcccct
    28861 catctagtaa ttaatattta taattgcatt tttactttta taaactttat cagtcaataa
    28921 atgtcgtgta taaatgttgc ttaaataata ccttaataaa aataaaataa tatcaactat
    28981 acaattgata taatgtatac cccataatgg acttaccgac gtatacatta ttttccataa
    29041 gcactatagt atttattaat attcaattat cggttaaaaa ataatacaaa ttttatttta
    29101 taaatataaa aacatttttt ataaatccct tgtgtcatat aaacatgctt attttttaat
    29161 ttgttaaatt cgtaatagca aaatataatc taatatttgt taaataatta tccaaaaaaa
    29221 atcaagtaat tattaatcaa ctttattttt taattgatac ttctttgtct ataatttaaa
    29281 caaaaggaca taaactttta aattatttat tagttttctt agtattaatg tttatatttt
    29341 tataaatata tattaataat ataaatagac taactaaaac catgcttatt tgctatatgt
    29401 tttatataat attatataac actttttaca ttagtaaagg ataaattgta taaagattct
    29461 gttaatttat ttttataatt tcatctttct aataaaaaca aagaagaaga cttaaaaatt
    29521 tataagtcct cttcttttca acgtgcattt ttgtgctata tttaattaat tcgaccttta
    29581 atttccatat ccttcctatg ataacaaaac tcttttattt ttttaatgat tcattatcat
    29641 ttaaaacttc ttttatatca agtacttctt tgttatcatc actcataact tcctttattc
    29701 ctttgaatgt tcctaggaaa ttaactgctt ctgaaggtaa aaccagtttt gttgacttac
    29761 cttcagccat tttttcaaga gcttccatag attttaatgc tagaatatta ttgtctatat
    29821 cagcctcttt cattgctgaa aaaactaatt ttaaaccttc tgctgttgcc atttgagttc
    29881 tttttatcat ttcagcttca ccttgtgcct tagcaatagc tgtctgtctt atagcttcag
    29941 cttcaccttc tgccactaat atagcagatt ctttttcacc ttctgctaca cgtaccatag
    30001 cttctttttt ggcttctgct gttaatattg cagattgttt ttcaccttca gcttgaagta
    30061 ttgcagctga cttattacct tctgcttgaa gtattgcctc tcttctttct ctttctgctc
    30121 tcatttgttt ttccattgca acttgaatat cctgaggagg cattatattt tttaactcta
    30181 ctctatttac ttttataccc catttatctg ttgcttcatc aaggatagtt ctcattttta
    30241 catttattat atctcttgat gttaatgttt catctaaatc aagttcacca attatatttc
    30301 ttagtgttgt agctgttaaa ttttcaatag cagctattgg attagctatc tcaaacacat
    30361 atctaactgg gtctgtaact ttataatata caactgtatc aatctgcata gttacattat
    30421 ctttagttat aactggttga ggtggaaaat ctattacaat ttctctaagg tcaattacat
    30481 atgccatttt atctaaaaat ggtattaaga aatgtacacc tgtttcagcc actttttgaa
    30541 acttaccaag tctcattatt atacctactt tagattgttt tataactctt atacaagtta
    30601 aacttattgc tacgactact actattaata caatacttaa aacaatttta gtacccatac
    30661 tataaatcct cctttattct attggtttgt cacattaact gtggcgtcta cttttttaac
    30721 aactaatttt accccttcaa tttttaatac ttctactgta gaaccttttt ctatcttttc
    30781 accatctata gaaatagccg tccatgtttc atgttcaact acaactagac ctgtgttatt
    30841 tggagaaatc tcttctgtaa caataccttt tttagacatc attgcttgta aattagtgtt
    30901 agatttatag cctttatctt tttttactat ttttttagta gctacgacta acattgctat
    30961 agaaattact gcaaatatta aaatttgtaa gaaaatactc tctataaagc tacttaaaaa
    31021 tataagtatt acagctccta cactaaacca tatcaatgtt aagcttggtg ttaacatttc
    31081 tgctattcca aataagactg ctactatcaa ccatattaac ttcatactat ctaccctctt
    31141 ttcatatgaa ttataaaacc ctatataaat tatatgttta tacaatgttt ttgaatataa
    31201 atttaaatta caaaacaata aaataaatta attaattaat agtattatat caacatactt
    31261 tgttaaaatt gttacaaagt agtatcaaat atcaccaatt atatatccaa caactctttc
    31321 attgttaatg aaatgttact tattaaatcc gtagcattta ccgtatacat tgctttgctc
    31381 aatttatctc ctatatagcc atgtatatat gctccactaa ctgtagcttc caatatatcc
    31441 ataccttgac ctataaatga agtaatcatt ccaagcaaac aatcacccat tccaccagtt
    31501 gccatacagc tatttcctgt aggatttata tatgtttttt taccatctgt tatgacagtt
    31561 tgataacctt ttaaaagcac caccagatta tatttttgag caaattcttt tgcaacatct
    31621 actctatgtt ctcttatata cccaattgaa tctcctgtca acctggccat ttctcccaaa
    31681 tgaggtgtaa ttacaaatct atttttccat tctaaaaact tataacatct gtccttcata
    31741 acgttcaatc catctgcatc taatactatt gggcaattag aattttctac tatcttaagt
    31801 aatttatcaa atgtttgact attatctccc atacctggac caaaaccaat tgcatcacta
    31861 gaattaagta atttatttaa tctttcttct tcaaaattta aagtcattgc ttctgtaagt
    31921 ctaatagata ccttttcttg cacatcttca ctactaatta atgttacaag tccactccca
    31981 ctcttaacag cagattcagt tgctatgaaa cttgcaccat aaaatccttt tgaacctgca
    32041 actatagata cttttccaaa atcactttta aaaccatgct tatctcttct tctaatatta
    32101 ttttttacaa aagtcttatc agttatgaac tcttcatcat ggtattttct tgtaataaaa
    32161 tctggaacac ctatcttttc tacaactaca tcacctataa gtgtgctagt gtcatagttt
    32221 agaaaacctc ttttataaaa ctcaaagcta atcgttttgt ttgctctaat acaagttcct
    32281 aatacatttc cattatcgct atctatacct gaaggaatat ctatagaata tgtatttttg
    32341 ctattatcgt ttactatgtc aataacttct ttaaaaatac cagttatatc acgttttaat
    32401 ccagtcccaa atatagcatc tactacaaca tcacttttag atagtctatc tttaaaaatt
    32461 gttaaatttt tattttttat aatattttgt ttctcaactt taataatttt atctacttca
    32521 ttttcatctc cataattttt ttcacttaaa tcatttttat taatatttat aatattaatt
    32581 cccatattta aaagtacatt gtaatttatt ttagagcatt cacttagttt ttcaagatta
    32641 cctactaaaa atacgtttac ttcttttcca tatgtattta gatgtcttgc tattccaaga
    32701 ccatctcctc cattatttcc aacaccacat acaactgtat aactattata catgtctata
    32761 tccatatttt tcattgcaga tataaccgca ttttccatca atacaatcat tggaatccct
    32821 acttcttcta cacatgcagt atcaacattt ctgcttaatt tagatgtacc tattagcata
    32881 aattatcact cctataaagt taaagacttc ttaaatactt accaaaaata tctattgaaa
    32941 tctttttaat cccataaata tcataaataa aatcactaaa actaagagtt ttgaaataat
    33001 ttaaaataac aaaaaatttt gaattaaaac aattatttaa tttattatac catataattt
    33061 aagttattat gttgatttaa aacctattta cactaattat ctaaatatct ctttattttt
    33121 ataatctttt atgacttatt tatatttttc atttttataa aaaaacaata attaagaata
    33181 taactatatt ctacatgtaa aaattttttt atttaaactc aaatttctga taatttgata
    33241 atttttcaaa atttatagtt gacttttatt ttttactgta ttaaactaat tactatacaa
    33301 aacagaaaac aaaattttca aaattattaa attaaaagga gaggtaaata tgaagacttt
    33361 attaaataaa caagtacgat tttttagtag ccaatttagt tagggtttgt acctaagtta
    33421 agacaaattg tcataacata gatacaagcc ccttaggatt atgattttta aggattgtat
    33481 ctatgttggc tatagtaatt gttgttaaag tttttatttt atcatcataa tatagagcca
    33541 catggattat actgtgtggc ttattcgaat ttttgccata cagttatata tactgtgtgg
    33601 tttttttata tcaaaatcat tttttaaaac caaatttaaa aaaccattta aaatattttc
    33661 aaaggggtgt tttatttatg tcaggtatta tatctgtaat gacgcaaagt ttaattttat
    33721 cgattatggc actgggggtt tatataactt acaaaatctt agattttcca gatatgtctg
    33781 ctgatggtag ctatacaatg ggtgcttcta ttgtagcatt ttctcttact aatggtattt
    33841 ctcctgtagt agcaacttta atggctatct tatgtggttg tactgctggt cttgttacag
    33901 ggattcttca cattaagttt aagatatcta acttactttc tggtatttta gttatgggaa
    33961 tgctatactc tatcaattta agaataatgg gaaaatcaaa tattcctcta tttagcttta
    34021 aacacttatt caatggggaa atatctccta tagttttagc cttagctttt gtattcatct
    34081 gtaaagtcct tttagattta ttcctaaaaa caggtcttgg atacacttta aaaggtgttg
    34141 gtgataactc tcaaatgatt aaatctctag gtataaatat cggttctata aaaatactag
    34201 gacttatgat ttcaaatgga cttatagctt tatctggtag tcttatggct caattcttgg
    34261 gattctcaga tgtaaatatg ggtataggaa ctttagttct tggaattgcc tctatcataa
    34321 ttggtattac actatttaag aaatttactt ttatcaaaga tactactgca ataattgttg
    34381 gctcttttat ataccaattc actatatact ttgcaatgag tttaggaatg ttatcaactg
    34441 acttaaaact aataactgcc atagttataa tagctttcct agctactggt aacttaaata
    34501 tttcactaaa aaaaaacaaa tgcaaagcta gtaccaaaaa taaatcagaa aaaagaggtg
    34561 ttgtagatgt tacaaattaa aaatctttca aagagtttcc ctaatccata tggtgaacct
    34621 aatactatct ttgaaaattt atcaatcgat atagaagatg gtgaatttgt aagtatcata
    34681 ggtagtaatg gaactggtaa atctacttta ttaaatataa tatccgggct tataaaagaa
    34741 tcttctggtc aagtattatt aaataaacat aacttgtcta atttagctga acacagaaga
    34801 actcaaatag taagtagagt ttttcaagac ccaagtcttg gaacttgccc ttctatgact
    34861 gttagagaaa acttgtcttt agctcttaac aaaggaaaac tattaaatct aagaaaatgt
    34921 cttcgttaca aaagagattt cttagaaaat ttattggaag gggtatctct tgatttaaaa
    34981 aaataccttg atgttcaagt aaaattttta tcaggaggtc aaagacaatc attatcacta
    35041 attatgtcgt gcttaacaaa tccatcagtt ttattacttg atgaacatac agcagcactt
    35101 gacccaaaaa catcaaatga agtaattgaa ttgactaata agattgtaag ggaaaaaaat
    35161 ataactacac ttatggttac tcacaactta aaacacgctc ttcattatgg tgatagattg
    35221 ataatgcttc ataagggtga agttgtatta gatgtaaaag gtaaagaaaa agaacaatta
    35281 acagttgaag aaatcttaga aaaatttgaa tatgcagttt aaaataatat atctattgta
    35341 ttaaactcgg ctttaaaata aagttaaaat tacaataatt atggttactt tgtaataatt
    35401 catatgaata tatgaacata tataacaata aatttttgag ggggatataa aaatgattaa
    35461 taaaaaaaga ttggcaagtt tgattttagc tggtgctctt agtatatcta tgcttacagg
    35521 gtgttcacaa ggaggagact ctggtaattc aaaacaagaa agtaattcta aaggtaaaga
    35581 agttaaaaaa attggtataa ctcaactggt tgaacatcca gcattagatg ccactaggac
    35641 aggttttgta aaagcattag aaaagaacgg atttaaagat ggagaaaata ttgatataga
    35701 cttccaaaat gctcaaaatg acatgcctac tacacaaagt attgcgagta aatttgcatc
    35761 tgataagaag gacttaatat ttgctatatc tactccatca gctcaggcag catttaatgc
    35821 tactaaagat atacctatac ttattactgc tgtgagtgac cctgttgctg ctggattagt
    35881 taaaactctt gaaaagccag gcacaaatgt atctggaaca tcagattttg tttctgtaga
    35941 caaaggttta gaacttctta aaatatttgc tcctaaggca aaaactatag gagttatgta
    36001 caatactagt gaagtaaatt ccaaagtcca agttgatgct ttaaaagaat atgcatctaa
    36061 aaatggattt aaagttgttg aaaaaggtat aactacttca aatgaagtta accaaggtat
    36121 ttctagttta gttggcaaaa tagacgtatt atatgttcct acagataact tagtggcttc
    36181 ttctatgcct atagtctcta aaatagctac tgagaataaa atacctgtta tagcagctga
    36241 atctgggcca gttgaaaaag gtgctcttgc ttgtcaaggt atcaactacg aaaaactagg
    36301 ttacaaaaca ggtgaaatgg cagttaaaat tttaaatggt gaatcagtat ctgatatgcc
    36361 tgtggctaca tcagatgata cagatatcat tgttaatgaa gatatattaa aagctttagg
    36421 tatggaaaaa ccttctaatg aaaatatttc ttatgtaaag actaaacaag aatagaaaga
    36481 tattttctat atacgattaa tatgcctgtt tctataaatt aatttataga aacaggcata
    36541 tatttttatt ttaatgtatt atctatttaa agattatatg taaatgctct taatttgatt
    36601 gtataaattt tacttgtata aactttatac aatcatattt attcttctat tttctttatt
    36661 actctacatg gatttccaac agctacagta tttggtggta tatcttttgt gactacactt
    36721 cctgcaccta ttactacatt atcacctata gtaattcctg gtgttatgat tactccccca
    36781 cctatccata cattatcacc tatttttaca ggagaaccat actctatgcc tgaatttcta
    36841 agttgtgcat caattggatg ataggctgta tagatttgaa cgtttggagc taacattaca
    36901 ttgtcaccta tttcaatttt acatacatct aaaaaaatac aatcataatt tgcaaagaaa
    36961 ttttcgccta catgtatgtt atatccataa tcacacctaa tattttgttc tacatttatt
    37021 tgcttgccaa ctgaaccaaa tagttgtctt aaaatatctt ctcttttttc atattcatcc
    37081 tctaaagtat tattaaacaa tctagttaat tttttacaat actctctttc ttttactaac
    37141 aattcatcat ttgcatagta tcctttccca gacaacattt tttctttttc agtcatatag
    37201 tttactcctt tttgttataa ttgtatctaa agcaaaataa atattcctgt ggaaaatcta
    37261 aatatattct gtcacctttc ttaaatctca ttttactttt ttccaattct atttgaatag
    37321 gtacacattc gttagataaa tcagtttttc taacatatat agtatatgta aaaggatttt
    37381 ctacaatgtt aatcaattcg aaacataact tttcatttaa atcttcatta gaatccaaga
    37441 ccttaatatg atgctccctg attcccacat attctatatt atcacctatt tctctattta
    37501 atgtcaactc gcatccccag tctgtagcat aaatagtatt tttatccagt ctatttaatt
    37561 tggatatatt tttacaccct gttatcttag cttctataag gtactttgga gattcaaaga
    37621 gctctttttt aggtctcttt ggaagacctt ctcctttgtt gtacactata atatcatcac
    37681 aaactcggta agcttcttca atatcatgag taacaaatag tatatctccc ttgtaatctt
    37741 ttaacatatt cataagttct ttttccatat tacttcttaa atgatggtcc aatgctgaga
    37801 aaggttcatc taaaagtaat atatctggag atgttgccaa tgctctagct agtgctaccc
    37861 tttgttgttg accaccagat aattgccaag ggtatctccc ctcaaaccca tttaatttaa
    37921 gtatatctaa gtaccttgct actatttcct ttttttcact cttacttagt tttaaaagcc
    37981 caagttctat attttgactt acagtcatat gtggaaacaa agcatagttt tgaaataaaa
    38041 atcctacctt tctatcttgt gttgataaat ttatcttctt ttcagaatca aatagaactc
    38101 tatcatttaa tacaatttta cctcttgttg gtttctcaag ccctgctata cattttaatg
    38161 tcatactttt tccagaacca gattctccca aaaaccccag agtacctttt tcttgtttaa
    38221 tttctacctt tagtttaaaa gaggataaat ctttttcaat atccacgtat aagctcaact
    38281 atccacacct ctttcctata attttctgct gaaattccga ccaataattt agtaataaaa
    38341 tcattgctat agatattgct acaataatca taacccacat catagcttta ttcatatctc
    38401 cgccttcaac agcaaaaaat atagctattg gcatagtttg agtttttcca ggtatatttc
    38461 cagctatcat aagtgtagca ccaaattctc caagagctct ggcaaacgac agcaccaatc
    38521 caccaattat tccaggccat gctaatggaa ctgcaatctt aaaaaatact ttccattcat
    38581 taagacctaa tgttctagca gctgacaaca tattattatc aatctgttca aaagctgacc
    38641 ttgaagttct atacatcata ggaaaagaca ccactactgc tgaaattaca gttgctgtcc
    38701 aactaaatat taaagtccta tcgaaattta ataaaaactt tcctataaat ccattcttcc
    38761 cacatagtaa taataaaaag aaacctacaa ctgttggtgg caaaattagt ggaagtgtaa
    38821 atagtccatc tataagacct ttccacttac ctctatagtt agccataata tatgacacaa
    38881 atattcctat tacaaaagtt attattgttg acaaaataga tgtcttaagt gatatccata
    38941 agggtgacca atctgttccc atctttccct ccttaatttt aaatggaaat agtgaaacta
    39001 ataactctat taatttcact atttccattt tattataata cacaattatt ttcaattttc
    39061 atttatttat atataattta tacttaatta cacataattt atttctaagt ttattctact
    39121 tttttatatc caaattcttc aaaaatcttt tgtcctgact cacttaataa aaattcttca
    39181 aatttcttag cagcatctac gtttttacta gctttaatta ctgaaactgg atatgtaata
    39241 ggcgaatgag ttttttcgtc tgttttttca actactttta tcttatcatt attgacagta
    39301 tcactgaagt aaacgaatcc aacatcagca tttcctgatt gcacccatgc taaaacttct
    39361 tttacatctt ttgcaaatac tagcttatct tttaacttat cttttaaatt taaattagtt
    39421 aacacctcat ctgcatactt accagctgga acactttcag cttcaccaac agcaattttc
    39481 ttcactttat ctgtagtcaa atctttcata cctgatacac tactgtcagc agaagaaata
    39541 agaactaaat cattttttac taaatctttc atagtatcag aaactaataa cttctcttca
    39601 tccaaagctt tcatttgttt ttgacctgct gaaataaata aatcacaagg tgctccttgt
    39661 tctatttgtt gttgtaatga gcctgatgct ccatagttaa ctgtaagttt tacatttgaa
    39721 tcaacttttt tatattcttc ttcaatcttt gccattgctt cttttaaact tgcagcagcc
    39781 gatatattta actctactga atcactactt ttagttgttt tttcttgttt tccattatct
    39841 tttttgtctt cattactatt gcacccaact gtccccaaag ttaaacatgc aactaatcct
    39901 aatattccca atattttttt cataacaatc tccctttttg taaatttgat acacatttta
    39961 acatgtttta ttatgtttta tcatgttttg ttatatatag tttaattata tatacatgat
    40021 aataaatttt caagtaattt atttacacta cttttaaata ttttgctaca ttttcctttt
    40081 tttaatgtta aaataacctt atatggaggt ggattatgga ctcattatca tctttgacac
    40141 ctgtcgaggt agctgaatta ttaaagataa caaaaaatac tgtatatgaa ttaatcaaaa
    40201 gaggtgaact tccttcttat aaagtaggga aaaaaataag agttgatact aaagatgttg
    40261 aagaatatat caacagccaa aaaactggta aagtaaagga tacacatttc aacaataaaa
    40321 atatagatat aaataataat ttcaaaatta ttatttctgg tcaagatgta atattagaca
    40381 ttttagctag gtctgttgaa aaaaaattgg atggaataag tacatttcgc tcttatatag
    40441 gtagttataa tgctttgtat gagttatata atggcagagt ttctatagca tcatcccatc
    40501 tatgggattt cgaaacggat gaatataata gcacttttgt taaaaagcta ttgccaggaa
    40561 taccatgtgt acttataaat ctagcttata gaatgcaagg tttctatgtt gctaaaggaa
    40621 atcctaaaga gataacaacc tgggaggatt taacaaaacc aagtataacc attgtaaata
    40681 gggaaaaagg ttctggaact agggttttac tagatggtaa acttagactt ctaaacttta
    40741 atggtaaaca tataaaaggt tatgataatg aagaattatc acatcttgga gttgcaagta
    40801 ctgtttctcg tggaatagca gatgttggtt tgggaaatga aaaagctgct ttacaagtaa
    40861 ataatatcga ctttattcct cttcacaaag agcgctatga tttagttatt aaaaaagaag
    40921 acttacaaaa tccagtttac caaactataa ttaacataat aaactctcct gagtttaaag
    40981 ctgaacttca aggtcttggc ggatatgatt taactgatac tggaaaaact atagcaaaag
    41041 tttaagatta aaatcgcaat ctattttata agatttataa tttttcacaa aatttataac
    41101 ttaaacacga aataaattgc gattttagtg tctcaaaaaa tttatgtctt tcattttatc
    41161 atccaataca aaatataata taattaattg tgcaatcata ttatattaat atatatttac
    41221 ataatagtat ttttctttaa tgtagattaa catatgatat gttttaaaca tcaatcccct
    41281 tgctttctta tatatatgtg gcaacacata tgagtttaat aaattatata caatgttgct
    41341 ttcctcttgt attttttcaa ccaacaagtt atttataaaa ttacctttct cattttcaat
    41401 aatctcactc caatttatct taacttttaa tatatatctt cccactaggt atacacactc
    41461 tacaataaat aataaaaata caatgcagtc agtacctgtt gtcttatata aattacccga
    41521 tactaatggc tttgcgaaga aattataaaa attcaaagta tcacccgtat aatcaaaaag
    41581 tattaatagc actcctagaa ctctcaatac tttaatattc aacatgtttt tatctttatt
    41641 atttttgttt ttcatatata ctacctctct tttctttaga tttgattgta atctaatact
    41701 aactctttta tttgaggtat aaatgaattt aattggtagt tattttcatt tttactagaa
    41761 attaattcac attactaaac aaaacttata tttaaacata aaaatagcct atctattttt
    41821 taataaatac aaaaataaat aagctactaa tattcaatta acttttatca cttaaaacat
    41881 tactatctat aaatttaaat attttattga agtatactgt actatcatgt tcaaatccat
    41941 caacatgacc aataccttct ataagccata ggtctttttt atcatgttta actaaatcat
    42001 acattttctt gctattttga taattacaaa cagtatcttt tgttccatgt ataaacagta
    42061 tgggtacatt agatttctca actgactcat atggttttac atcactgtac caaaatccag
    42121 atttaaactt attatataaa tctccacaag tcactacata attgattaat atatctggta
    42181 ttcgtttttc tagtactccc attctaattg catctttcat ttcagaataa ggagaatcca
    42241 gtatataaaa atcgacctta tcatcttttg aatttatctc tgaatgcata gcagctgtcc
    42301 ctgcccccat ggaaaatcca tgcactccta atcttccttc aggaaattta ttttttacaa
    42361 atttaactag actatctaaa tcataccttt cataaagacc aaatgtgtaa ttatctccac
    42421 cactattacc agtatttctt tgattataaa ctaatacatt ataaccttta tctaaatatc
    42481 tatatgctac ctttaacatt tcatagtaac tacttccaat tccatgaaca agtatcatag
    42541 tatctcttgt ctttatattt gaagttataa aaagactttc aagcttgtaa ttattagaac
    42601 tttgtatcat taattcagat gtcttgtagt tttttaattt ctccagtggt ttatcttttc
    42661 tctcagaaaa tatttttact atatcttcgt tttttattaa ctgctctaaa ccaactgaac
    42721 tattatacac taatttgcca aatatataag atacaattaa taggattaat agaaacacaa
    42781 ttgatataat tataaattta tttcttaaac taatacaatt tttaaaacta tttttcatat
    42841 ttatttacca tacaattttc ctatattata ttttctaagt aatagcataa ttgattacac
    42901 tattcttata atttctatta tacctactta tttattaaaa atacaaatta tattttatta
    42961 atttttacta cttgtaaatt attatcttat acaatgaatt tgtattatat aataagtatt
    43021 tttaggattc tgttacataa tattatttaa atattcttct atatttctct tcttcttctt
    43081 cagtaaacac attaaataca acttttaaat ttttttcagg attttctttt agccatagtc
    43141 taactctact tacagcaaga ttagctgcct ctttttttgg ataaccaaat acacctgtag
    43201 aaattccaca aaaaacaata ttttttattt catcaatttc ttttattgta tttaaacatg
    43261 atttataaca atgaagcagt tgcttttctt gctctttact tggctgacca ccagatacaa
    43321 taggtccaac agtatgtact acaaattttg caggtaaaca ataacctcta gttatcttag
    43381 catctccagt atattctaaa tgcccttgtt tttttattat tttgtcacaa tcttctctaa
    43441 gtctaggacc tgcgcatgaa tgtatctcat tatccacgca tagatgtaat ggttgtaaac
    43501 accctaataa cttgttattt gcagcattta ctattgcatc tgctcttaaa ttcgttatat
    43561 tacctctcca tatggcaatc ccttcctcta cttcttctat atcatttaca tctactaact
    43621 ctctttcttc acattcaatc aacaataaat tatgtaacat attaagtatc tctggagcaa
    43681 tttcttttgg tggatataca ttcaaaagtc ctctaagtat atctctaggc ttaatttcat
    43741 catttgataa attgtatatt ttagaaggaa cttcttttga aaaatatgca attaaagtgt
    43801 ttatattttt tcttctttgt tcgtcagtta gaggcttgat agttttatca aaatcctcaa
    43861 ataaatttac atcatcagca taatctctcc acttcatagc catctctcca ttcttgtatt
    43921 ttagacttaa aaataattat gtatttatgt acatatttat ttatttctat aaacacctac
    43981 ataaatcctg ttaaaagtgt aaatttttta ttatgcaact tctctggtta tttctattga
    44041 ttgatagtaa attattgtac ctaaatttaa tccaactaac aagtaactaa acctactttc
    44101 ctaactgcaa aatacactat gtttgccact tgtatctcat ttgtaaataa ataaagtccc
    44161 tacaaataca ttaactaggc tatgtactaa actgtaggaa ctttaaaaat atattattct
    44221 taattaagtt ttggccaata atttttattt gcttctatta aatcatctag taattctttt
    44281 gcaactgttg cactaggaac tgtcttagat agcataagtg cttgccacaa tttattataa
    44341 gacttctcaa tccaagcatc aactactaat ttttcaactg ctaattgttg ttctattaaa
    44401 cctttttgaa atgttggtat tttccctatt gataatggtt catacccgtc ttttccaact
    44461 atacatggaa tttcaaccat agcatcatct tgtatatttt ctatagctcc attattttga
    44521 actatcaata acatacgctc ctgtgtatta aaagctagag ctgtagctaa atccactata
    44581 aactctgcat gtattcctat cttaagccca ctgcccttag aatgtccttg cttttctatc
    44641 aatgcacatg aaccaaaaac ttctttttct cttccatcaa taacttcatt ggcacgagta
    44701 taatttacat cagaatgatt tacaacataa tctggaaata gatagtactt taagtaacta
    44761 cttggtattg tagttaaatc tgtttttact atttctttag taaataaatt agtttcaaac
    44821 caactatctt tcttgtcatt tttcattcct tcttcaccat ttataaaacc atattctttt
    44881 atatgttcta ctaattttgg taaaagttca tttccttttt tatctttaat tgaagtatac
    44941 caaccaaagt gatttaatcc aaagtatctt atatccatat gtttacgaga tttgagtcct
    45001 gcaatccttg ctatattatg ttccatacct attggcatat cacaaatatt tattacccta
    45061 gaattaggtc tcaaccttct aacagcttcc gctattattg atgctggatt agaataattt
    45121 aacatccaac aatttggaga atacttttcc atataatcta tgttttcaag aacaccttct
    45181 atagacctca ttccataagc tattccacct ggtccacaag tttcttgacc aactacccca
    45241 tgttttagag gtatcttttc atctagttct ctcatttcaa gttttccaac tcttatatga
    45301 gctaaacaaa aatctacatc tgtataagcc tctttagggc atgttgttgc taaatactct
    45361 atattagggt ccttttcctt tattagtatt tcacaagctt tagctacctt attttgtctt
    45421 tcttcatcat tatcatataa tttgattgct cttaatggta acctatctaa gttatctagc
    45481 aacattaata tgatttctgg ggtatatgta cttcctcctc cagctattac tactgaaaat
    45541 ttttccataa taatatctcc ttttctattt aaaaatttac tgtatttata aataaattta
    45601 taaatactag tactttaaag taaaagggag ttcatttatt aaatctattg atttaataaa
    45661 ctatagccaa acttcaagca ctatttacaa gaaatttaat tcttattaat tcttgggtcc
    45721 atcatctcaa atatatctac aagttcagat actaaagaat gagcaaataa tgcatttgaa
    45781 taatggtctt cagagtgcac aactaaaaaa tcagtcccac tatcttcact attcatagca
    45841 tttgatagta attctaaatg atgctttgat gctgtttgta ttttctctga ggctgaattt
    45901 aaaaggtgtt ttgctttatt gtagtcacct ttttttattt ccttaagaga catcattaca
    45961 tcacttttag catctcctgc ttctgatatt atactaaata ctttttcttc catttcaggt
    46021 accatatcct tctccttcta atgacttgtt aaaaatcaaa gctatcatca tctaatgttg
    46081 tagctaattc tgcattttta tttaattctt ccttctccat tatcttaaag aatggataat
    46141 atatcaaggt cataagtatt atacttgcaa atactaatac gattgccttc caatctaatg
    46201 tcatcaaaaa tgctgcaacc cctggaggta aaaagcctgg tggttctgca ataggtaatc
    46261 ctactaatcc tacttttaat gccataaaat taagtgctcc aaccaataca ggtccaaata
    46321 caaatggtac aaacatatat gggttcataa ctattggtgt tccaaatatt actggctcat
    46381 ttattccaaa tagtgatggt aaaatcacaa cttttcccat actattaaaa ctcttacact
    46441 tacttcttga cataaggtac actaatccca aagttatccc tgaaccagtt acttgcaaga
    46501 aaccatagta aaaacctatt gtaaacacat attttgggtc tcctcctgct gctatcagtg
    46561 ttgcattttc tgccatatat gtagctgcta ttggcatcca tatacttgaa gttattgctg
    46621 ctccatgaag cccaaagaac cataataatt gagttataaa tagtattata gttactgcaa
    46681 aaacattatc tacactgctt atagctggtg ctaagaaatt cattataata gctggtagtg
    46741 gttgacctga gacattttta gttattgctg ctattgctgt aaataacatt atacatacta
    46801 tcattggagt taagtttcta aaacttttat ttactacact aggtacttct tttggaaatc
    46861 taattacgag atttttatca ttcataaact tagtaatatc aactactaaa agtgctacta
    46921 atatacttac aaataaacct tgtgcatcta aataacttgt atctaataca ccatctacta
    46981 cttgcccaca tacaacaagt tgtgcaacaa ctgctgtcat acctatttct acatgattaa
    47041 gattatattt tttagctagt gcctgagcta taaaaaatgc tgaatatata gataataaac
    47101 tcatagtaaa tttattaggg ataagtaatg tatccatatt ttcagataat aatgtttttg
    47161 cacttccttc aggtaacata ttgtttaatg ccataaataa catacttaaa gaaccaacaa
    47221 ttattattgg ggtaatgctt atcatacctt cttttatagc ttgaagatgc ctttgttttt
    47281 caatcttttg tgctattgga agaagaaatc ttcttaaatt attttgaagt gcttccattt
    47341 ttattccccc caattatcta tttttatata attcgattgc cgacttcata acagaaggag
    47401 catccatacg accataatgc ttagtatcta ttaaaccaac tgctattttg taattcttac
    47461 aagcttcaac tacatcatct tccttaaacc taatttgtgg tgctacaagt actacatctg
    47521 tatcattagc ttcaatgtat gattttaaat tttcaaatga tgttgcctct atatttatag
    47581 ttttagtttt taacttttca tgctcactac aaaaactttt catcttttcc acaagtacac
    47641 ctgttgaagc tccatttgca catactaata aaatattcat aattaccctc ctacaatatc
    47701 taacctcttt tgttttctaa ttttttatca gccaattctt actctaattc ctatcagttt
    47761 ttactttaat tcttattatt ttattttaat tcttattaat atttactcta attcttagta
    47821 ctgccaatga ttaaacttga aagccgtatc tataacttct tcttgcttat atttttctaa
    47881 tatttttaag tatctttctt tataatcatt atctacttct ttttctggta ttactatact
    47941 agcttcattt aaaaagtgga atgaatccct tcccatttct aatcctctat atgtatgctt
    48001 gtcaagtgcc acgtccataa cttctggaac tttacccatt gcaaatcctt ttataattat
    48061 attttttaat aaatcacttg atctatcttt ctcacatgca caaagatatc ttattgcatg
    48121 tatgaaaaat aaaggtctgt ctccatctgc atatgaatat tcctttctta cttgatttaa
    48181 attatttatg attattacag ctgatgggtc ccccattcct atatcttcaa ctgatattgt
    48241 aagtatcctt ctccatagct tatcttctaa ttctggtgat gatatatata gttcataagc
    48301 aaattcacaa gcttcttcca ccatatttct tcttatagct ttttgaaatg acgatattat
    48361 ttcgtctgca ctaaatccgt ttcttgtagt cattcttgcc catgggtcat ttgccttttt
    48421 atctcttaat attttatctt gcatattatt tactcctttt tatttaaatt ttaattattt
    48481 atattgctca tttaataata taagcaagta ttatgccagt ttttttagac actttaaaac
    48541 actgttattt caatcatttt tatcatcaaa acttagatac tttgtctaag tatatttata
    48601 tgtgtctaat attaatatta ttttagacta aaaaaaatta ccaaataagt ttttatactc
    48661 attggtaatc tttttcgatt atttctgcat attctaatat taataatatt tgatagcact
    48721 ctttttcatt aatttctata ttatattttt tatctaattg agatactata tcttttattt
    48781 tgcttagact cttgtgataa tcaagtgttt tttctttatc aagcttttca atttctctag
    48841 tatttccaat caacccatct accatgaaag ctaaatgcat cataagtcca attactttat
    48901 cgtatttctt ttctatatta aatactaaaa acaattcatc agacacatat tttatatctt
    48961 taaatatcct attataatta gagcttttta aggatgtctt taaaccttca actacatcat
    49021 cataacctat acttatcttt ataatatttt ttaatttatt gatattttca tccttatcta
    49081 tatctttttt gctaatatag tcaattcctc taatattaat tctttgttca ttgattactg
    49141 caacaatatt actactttct ttaagtttcg taatatttaa acttaaatct ttttctgttt
    49201 tatatgggac agatataata tctattccat ctaagtacct actcatcttt tcttctaata
    49261 tttttcttgt tttattatct acaccttctg aaacatgtga tgctataata attgttttag
    49321 acagattttc tttattttga atttcattag ttccaaaata gtactttctc gtgttagtga
    49381 tagagttgta tacgtcattt aaaggtaatc ccatattggc cttctgaact gcttctaaca
    49441 cagttaatgt cgtcaccata ggaattactc ttactccaca ctttttttct ttctttataa
    49501 tttcatcaaa agagtttaat gaacccatat ctgtaaatag taatacatct ttattgtcta
    49561 tattattaat taaattttta aaatctacaa taacttcatc atagctttta tctaacttca
    49621 tatcgaaaga aatagcactg cactttccaa taatatcacc aactgctttt accatactac
    49681 ttgctgtagt ttctccatgc atagcaacta taatattaat gttattcact attttatttt
    49741 gttcatcttg tttagcttgt actatgaata atgtaatata tgctacagtt tctatagata
    49801 aaaataaatc aaattcattt tcaattattc caactatttt taatgctgtt ttaaattcac
    49861 ttctgttatt tcttctaatt tgattcaaat ctatgttgtt tgtagagcta cttttatcca
    49921 atacgctttt tatataaatt gccattgact taaatattga ttcacttata tctatttctt
    49981 catcttcttt aataatttgt cttattgatt cacacatgct tttaaactta acattattaa
    50041 atagagaagc atctgctata ttcatttcta cagatttatt aagattagta tttactgcat
    50101 taataatatt tatatcattg tagttaataa cttcttcttc tcctaatgac gtaaatacaa
    50161 aatattctat tccatgtgtt ataacttcat ctgctttaat agacttctct ctataatcat
    50221 cactcacttc atttatagat ttatcaaaat attttttctc tatataaact ggttctttat
    50281 tatctctttt atatcttagg tatccatttg caacagctaa ttttatatca ttttgaagtt
    50341 gacctacatt atttttacaa tcataaagta atagtgattt aattatttct ttatgtactt
    50401 ttattgaaat agaaatactt tttgattctt ccttgaaaaa atttttgact aattccattc
    50461 tttcaatcat tgtcctatct ctcagtgatg gtatttctat tttcattggt attcttctat
    50521 tgaatgtatc taatagtgtt gatgtcggat tttctgtagt agcacatatt attaatacct
    50581 tagactctct ttctttcgtt gcatctccta gtcttttaaa tgttccctta tctataaaag
    50641 taaacaacat ttcttgacct tctgctggta gtctatgaat ttcatctaaa aatagtatcc
    50701 ctccatttgc aatttccaaa agaccttttc tggaagattc tgcacctgta taagctcctt
    50761 gttctacccc aaaaatatgt cccataagta attgtgcatt attagcataa tcagcacaat
    50821 taaatgttac aaaaggagct ttattttttc taattccact atctatagaa taatcgtaca
    50881 tatatctagc aatcatactc tttcctactc ctgtttctcc atagataata gtatgaagtc
    50941 catttgtagg atagagcatt gcgaccttgc atttttctat tataggtctt aaactatgtt
    51001 ctttacctat tagtgtttca aaactatctt tttttatttt gttttctact tttgttcctt
    51061 tttttatgcc aagcaactca ctttgtgtat caagcaattc attcttgtta aggttaagat
    51121 ttgcagggat ataatacaca ggtcttcctt ttatcttcgt aaccataccc tcattgaata
    51181 attggtttaa atatgtactt atattgtttc ttgcaattcc tgtcttttct gataattggt
    51241 tagctgtaat ccctttttca ttttccctat atgatgattc taaaactttc attactttat
    51301 cttttttata tatcattaca agctccccta cattatagta ttttattaac taaaacccct
    51361 atacacactt tattttttaa taaactctta ttctttaact aaggttataa tttatcaaac
    51421 tttccttact ttaaattata gaaaattatt gtagaaaaaa taagattatt gctcattttt
    51481 tctacattac tatttttaat tttatagtac tttcttaaca acatacttta cttgttttta
    51541 attttattat atttgaattt attatatttg aaaagtagaa ataaaaaacc ctattttgga
    51601 gtagttttaa aatttctcca aaaatagggt tttagtttgt atttcaaata aatacctgtt
    51661 caagtatttt tatactaaac aacttttaaa ttttgttgat atttatttat ttctgattta
    51721 gaagaatata caaaatgtcc atctgaaacc tcaatccaac ttaatgactt ttcatttgaa
    51781 caatcatatc cattagaatt atactctatt ctatttcttg acttagcata tctagggtca
    51841 ggaacaggaa ttgcagaaag tagtgatttt gtatatggat gaataggatt attatacaat
    51901 tcatttgaat ctgccaattc tactaatttt ccattataca taactcctat gcggtcacta
    51961 atatgtctca ccatagataa atcatgagct ataaataaac aagttaaatt cttttcttgt
    52021 tgcaattttt taaataaatt tactatttgt gcttgtatag acacatccaa agaagctata
    52081 ggctcatcag ctattataaa ttctgggtct actgaaagag ctcgcgctat gccaatacgc
    52141 tgtctttgtc cacctgaaaa atcagatgga tacttatttg cataacttct atcaagtcct
    52201 actagcttta gcatctcata tactttattc attctatctg ttttattttt acagatacct
    52261 tgaattttta gtggctctga aattatatct gcaattgtca tacgtggatt taatgatgaa
    52321 gtagaatctt gaaaaataat ctgcatactt ttgtttacat ctttttttat aaatttgtac
    52381 gtttttttat ctgatatgca atttcctttg taaattactt ctccaccagt agattcatgt
    52441 agtcttatta tagttttacc agttgtagat tttcctgaac ccgactctcc taccaatcca
    52501 aatatctcac ccttatatat atcaaaactt atatcatcaa ctgcttttac agtagtactt
    52561 ttgtccaaat gaaaatattg ctttaagttt tttatttcca gtattttttc tctattcatt
    52621 agaaatcacc cttccacaat ttactctaac tggtacatct acttcaggtg catctgggtg
    52681 caataaccaa gttgctgcac tatgtgtatc attaatttta aacattggtg gctctttttc
    52741 ataatctatc ttaagtgcat ttttattcct tattgcaaaa gcatctcctt ttggtgggtt
    52801 caataaattt ggaggcattc caggtatatt atataaatag tcatcctgcg aatctaaagt
    52861 aggtaatgaa cccaacaacc cccaagtata tggatgtcta gggtcataaa atatatcctc
    52921 tacagttcct atttctacaa tctttcctgc atacataact gctattctat cagctatagt
    52981 tgcaactact cctaaatcat gagttataaa tattattgac aaacctattt tatgttgtaa
    53041 atcctttatt aaatcaatta tttgagcttg tatagttaca tctaaagcag ttgtaggttc
    53101 atcagcaatc aatacatctg gattacaggc aagtgctata gctattacta tacgttgtct
    53161 cattccacct gaaaaatgat gtggaaattg tttaaatctt ttctcaggat tatcaattcc
    53221 aaccaattca ataagctcta tggctctctt ttttgcttca cttttactta taccttgatg
    53281 aatgattaca gcttctgcaa tttgctttcc tattgatata gttggattga gagatgtcat
    53341 agggtcttga aatatcattg atatattctt tcctcttata tcttccatct ctttttcagc
    53401 cttcttaacc aaatcacttg atttaagtaa aacctctcca tttttaatat atccattgta
    53461 tgggagtatc ctcatcaaac tcttacacag tacagatttc ccacaaccag attctccaac
    53521 tatagccaat gtctcacctt tttttagatt aaaagataca tttcttacag cctgaacttc
    53581 tccttcttct actttaaaac ttacagatag attattaacc tccaataaat gttccaaaaa
    53641 ccatcaaccc ctatgctatt caaaccttag ggatatattt ttatccctaa ggtttctaat
    53701 taatttcagt attattcaat tgtccagtca gctatgttcc agaatatacc tacaccatga
    53761 tgacctaaaa ctgtatcagg tgttaatcct tttatgtttg gttttccaac atatattgca
    53821 tctatataag caataaatgt ataaggcata tccttagtca tttctacttg gaattgttta
    53881 tataacttta atttttcatc tttatcttct gtttctcttg ctttttgaag tattttatct
    53941 atagtaggat tagagtaagc actgtaattt gcacctttat ctgttccaaa tactttatat
    54001 gtatggtcat ctgggtcaaa tggacttccc caacctatta aatgagcatc ttgattagcc
    54061 caatctgttt cagttacaac aacagcttta gcatcaacac caatttcttt taactgttgt
    54121 gcacatattt tagccatatc aactctaact tggtcactct cacctgctgt tatctcgaaa
    54181 gctaacttag taccttcttt ttcatagatt ccatcagaac ctaatttcca acctagcttt
    54241 tcaatttctt gtttagcttt ttctggatta tattcaaact tttctatatc aggattatta
    54301 tatggtccca tttgtaaagg tgaatatgct ggtacaccat gtcctaataa tacactgtca
    54361 actattgctt ttctatctat tgcatagctt aaagcatttg gtaatccttt agctttttta
    54421 tctttaaaga atttagaatt aaaattgtat aatatacctc tatagtcggc tgttttcatt
    54481 atatttactt taaaattctt ttcgtctttt tcaaagttag acatatcttt aggagttatt
    54541 tgagctaggt ctaattctcc tgattttaat tgcattgcct tagccttatc atctggaaca
    54601 atcttaaaga ctactttatc taatcctggt tcttttacaa aataatcact attcttaaca
    54661 agtgttatac tttgaccttt gtcccatttt tcaagtttaa atggtccagt acctattggt
    54721 ttttgattaa attcatcagt agctatatcc ttaccttcca aagcatgttt tggtaatact
    54781 cctactgtta aataatcaag cattgctgta tttggagctt ttaaagtaat ttttatagta
    54841 ttatcattaa ccacatcaat ttttgttata tcttcataat ttgatgctat ctcagaagca
    54901 ttatctggat tcattatagt ttctattgta aacttaacat catttgctgt aaatttttct
    54961 ccatcatgcc acttaacatc atctcttaaa ttaaaagtat atgtatttgt tgcctcatca
    55021 aatttccagt cctttgctag acaaggaacc accttattat tttcatcatg agctgttaat
    55081 ccattaaata ttaacgaatt tatttctcca tgttcatata gtgcaggatt tatacttgta
    55141 tagtcattac ttccataaac aagtaccttt ccatctttag gcgtatctgc cttcttatct
    55201 ttgtctcctc cactagaaca acctgccatt agactaagta tcattactaa acttaaaact
    55261 tttaacttct ttaatttcat gatgctcccc cttttgcttt ttataaaata tttttcaaag
    55321 ctttgacccc atttatttaa atagatattt caaatacctc agtatttgct tatttaatac
    55381 tcaaatgctg atttataaat tactagattt tttattatta ttctttctta tataattacc
    55441 tatatttgtt atacacacca atgtggtaac caaaaatata cccggaatca gtataatcca
    55501 ccatctattt gaaagtaatg cttcctctga caaagataac atacttcccc aagaaacaat
    55561 ttctattggt aaaccaattc ctaaaaagct aagtgtcgat tcagtaccaa tagctgcgcc
    55621 tatgtttgtt acaaccatga acattattga tgccacaaaa tttggaagta aatgttgctt
    55681 taatacatag aagaatcctc ctcccatgct cttagctgct agtatgtatt cgctatttct
    55741 tatttgtcta acttctgttc tcactatctt agatatattc atccaacttg ttatccctat
    55801 tactatggac atagatactg gatttgaatt tccaagtata gcttgtacaa atattataat
    55861 taatattgaa ggtatactaa gtatgatttc tgtaaacctc atcattgcat catctacgag
    55921 ttcagatgct gaaccactta tactaccata aacaattcct ataacagttg atattacagt
    55981 ggaaaatagt cctataaata aagatatttt tcctccatac catatcatag aatatatatc
    56041 tctacccatt gagtctgttc caaataaaaa agttttattt ggagctaaat tagaacttgc
    56101 taaatccatg tatgttggtt catgtgtcat tataaaagat gagaatacac ttccaatgac
    56161 tatgattgat aaaataataa ttgatatata tggtaattct ttaatttttt tagataaggt
    56221 tttctttgtt tctatatgtt catcttctgc tactaaaata taattttctc ctacaatttc
    56281 aaaatcacta tattgtggct tcattagtat cacctctatc atatttcatt ctagggtcta
    56341 ttttattgtt tataatttga gctaacatat tcccaaatac tactaaagcc cctgttatta
    56401 agcataaaac taataacata ttataatcat gatactttgc actttcaaaa caaagtgttc
    56461 ctagcccagg ataagaaaaa actttttcaa ctacataagt tcctcctagt atatgaggta
    56521 tcgaaatggc cattatacta atatatgatg gcattatatt tctcaggcaa tgcttaaaaa
    56581 caatagttct attatttaaa ccttttgcct tacataaaag cacataatct tctcttattt
    56641 cctctagtaa tttatttctt atcatatatg tgtaatacca tagatggctt aatataagta
    56701 ctgtaagagg taagattaga tgtgatatcc tacttaatat actggactct tctcccattg
    56761 aataagcacc actacttgga agtatactta agtttatact aaatataagt atgagtacta
    56821 aggcaaccca aaatgatgga atacagttgg ttattgttcc taatttgcat atgattctat
    56881 caatgagctt atcttcatgt aatgtacaaa atattcctaa caataaggct agcacaaagg
    56941 taagtatata tcctgaacca cctaatatta tagtgtttat atagacatca tttataacag
    57001 aagtaacatt ttgtttatat ttaaatgaaa ttccaaattc cccttttgat gcatttgaaa
    57061 tccattttat atattgactg tatattggtt catccaaacc aagttttttc atagcatttt
    57121 ctttttcttg tgtactcatt ctttctactc catccccata gtaagagatt aatgggtctc
    57181 ctggagcaag tcttgccatg taaaaaacaa taaaagataa taaaaacatt actaaaataa
    57241 actgcaacaa ctttttcagt atatccttta acaaacccca accccccttt gttgcaataa
    57301 aaaaaaccac ataaaagcaa acgtaaagta acgttaaaac cttcgtggtt ccattatcat
    57361 taaacaaaat taaattttct atatttatct atgagttaat tttagcatca tttattaact
    57421 gtgtaaacaa actttttaaa aattgttaaa atttcatcaa attattttat ttatacctaa
    57481 aataaaattt ttatattcta ttcttcatta ttttctataa aattataaaa ttttaggttg
    57541 actatataag aaaagtatat tatattagtt tgtatgcaaa ccatttaaga ggtgatttta
    57601 ttgaaaagta attatgactg ttttagaata gccatgctct taaaagaact ttattctaaa
    57661 actatgtaca cagtagaaga aaattttaaa gaaaatggat taacacacca acagattata
    57721 gttataaaac tgatagctca taatcaagaa cttacaatat cacaactatg tgatgaaatg
    57781 tctttagcta aaggtacggt ttcaggcata atcagcagat tagaacagat tggatatata
    57841 gaaaaattca agaaatctaa tgataaaaga aatacatacg ttaagtttac aacaacagga
    57901 tttgaatttg ccacaaattt taaaattaaa atgcaagaaa gttttgatga tatttttaaa
    57961 aattgtgatg aaaacgaatt gagtgactta gtaaaaaatc ttagaaatat attggcaaaa
    58021 gtaaaggaga gataattatg aattataaat taatacttgc aatagtattt ataacatcag
    58081 ctttaatttt ctacactata ggtgtatttg gagaaagaaa ggcaaaaatt ttaaaaaaga
    58141 aacatgtaat tatattttgg cttggtttta tatttgatac tttaggaaca tttacaatga
    58201 gtaacatagc caacagccat acttttgaag taaaatctgc tttatcacaa aaccttcata
    58261 gtattacagg tcttcttgca attgtgctta tgctttttca tgcaagttgg gctacttttg
    58321 tcctatacaa agatgatgag gaaaagaaaa aattctttca taagtttagt atagttgtat
    58381 ggactatatg gttagttcca tattttatag gtatgtttat tggtatggct ggatagtaaa
    58441 ataaaaagtg tgaaagaagg atgtaggtaa atttgtataa gacaaattta cctacatcct
    58501 tctttcacac ttttacatat ttatttataa tactccatta tttctttcat gttccttaat
    58561 acctatatag aatatttaat tgtttctata gtattttatt attttctcac actttttcat
    58621 atatatattg ttttactatt tcttcatatg tatatatgaa atattccatt atttctataa
    58681 atgttttatt atctttctca tactttttca tatatatatt gcttcactat ttttcttatt
    58741 tcttcatata catatgaaat atttcattat ttctataatg ttttattatc tttctcatac
    58801 tttttcatat atattgtttc actatttttt ttacttcttt attaaatact tatgtataac
    58861 atacatttaa taaacgctaa ctattaaaca cctaatactt gagttactcc tggaacttca
    58921 ctcaccaaaa cattttcaat aatagctttg attgtcatag tcgctcctgg acacccacta
    58981 catgcccctt gtagtctaac taaaaccaca ccattttcat ttacatctat aagctctaca
    59041 tctccaccat ctctttgtaa tactggtttt atcttttcct caagcacttt ttcaactttt
    59101 tctctcatag ctattccccc ctgaaatatt ttattaccaa aattatacca atggtttaaa
    59161 tttttgtcca tctaatgatt tatcaaattc aatttttgct tcatcaataa ttttagtatc
    59221 cataaataca tcataagcac tacaagccag tactttagct gaatttatca tagcagaaaa
    59281 tcctatattt gaacctgctg atgaacatga ctgccatgta tgacttgcaa ttccaacagg
    59341 ccaagctgcc attgcaaatt gagccactgg tattacataa cttacatctc caacatcagt
    59401 agaaccagct agtcctttat ctttgtcacc gtcaactatt tccttgtgta tatagctttc
    59461 tacaatagat ttatcatttt gtaatgatgt tgctacacct aatctttctt ctctagtaag
    59521 agtatcacac aacttttttg caaattcttc ttcttcagga gtatttttag ggcaaccaat
    59581 aaaaaccata ttgtcataaa ctaaatcagt caaacattgg tttggtatat agtcatatat
    59641 tccatctgta accttatact ccatttcagt ttctgtcatc attgctgctc cttgagctac
    59701 ttttattaat ctatcaagaa cgtgttctgc atcttttgct tttttacctc taataaagta
    59761 ccaactttca gcaaatccag gaactacatt aggtcttcca ccaccattag ttataacata
    59821 gtgcattctt atagagtcaa taacatgttc tctcaaataa ttagctccaa cattcataat
    59881 ttcaacagca tcaagtgcgc ttctaccatt atgaggagct tgagctgcat gggctgttat
    59941 ccctttaaat ttaaatttta cagataagtt tgccagactt ccacctctcc aaggtgcatt
    60001 tatatcaaaa ggatgccatg taaatgcaca atctacatca tcaaaacagc catttataca
    60061 cataactgtc tttcctccac cttcttcttc agcaggacaa ccaaaatatt ttattgttcc
    60121 attaaattta ttttcttcta ttaatttttt tatagaaaca actgctccta cacctgctac
    60181 acccaacagg ttatgcccac atccatgtcc agcttttcct tctaccaatg gctttctttc
    60241 tgcacttaca cattgtgata gctctggtaa agcatcatat tctccaagta tgccaatcac
    60301 aggtttaccc tctccaaaac ttgctataaa tccagtaggt aaattttcta cttcttcaat
    60361 tttaaatcct tttgacttta ggtattcttt ttgaatgcta cttgcatact tttcttcaaa
    60421 ggctaattct ggattttccc atattttctt agataaatca attaattctt ctcttatttc
    60481 ttcaacatta tttatgatat actctttcat aattttcctc caaatatatg tatttttgat
    60541 atgctttaca gattatatta tatactaaca ttctatttat tcacaatttt ttgttaatta
    60601 attttattca tatgctcttc tatggagtat atcttatctt cactttgcct cttcataaat
    60661 ttaatgtact ctatcttcca taaagtagtt tcagttttct catttaacat aaattctaat
    60721 atattaattt ctctcattct aatatcttca taaaatacta cactacccaa tattgccaat
    60781 tctaattcac ttaatgatgc aaacaacatt aaatactctt ctccaaataa acattcagat
    60841 tcaagaatat cgataaagtc ttttttagca ttgatatttt cctttattat tcttattttt
    60901 tcaattatag atgtactatc taatatctca ttgaatatct ctctaaacga ttcatcatcc
    60961 aatttacttt catcatcaac aatataatct tctaagtgtt catttttatt tttactcaca
    61021 gttaccatac tttttaaagt gttacttttt attgagctta gcacagattc aataaatatc
    61081 ttttcatatt ttttaatata tcttattaca tcttcatctt ctatgcttaa tctttttatt
    61141 aatacttcaa ttgcttccat aagtagtaaa gttatttttt tatttattct aatttctctg
    61201 ttaatttctt caaaatcatt ataatccaaa ttactatcta cttcagtgtt aaaactatca
    61261 tctacttcaa tcaattcaat tatattactt tcttcagagt ctataacttt atcttcagta
    61321 atattattgt acatattttt aaattgtttt tctaaaaatt catactcata ttttgaaatt
    61381 tctaaattag tcacttcatt tcctaaaata gtagaaaaaa tacaattatt cataataagt
    61441 tcaaataaat ttacaagtat aacatcacaa tctattttat aagtcatccc atagtcataa
    61501 aataattttt ctctatcttt tttcttaaat aggttacaaa atctattttc tatatctata
    61561 ctctcaatat aattcttcac ataataaata cccttaacat ccatatcatc tagtgccaat
    61621 ggataatcta tacttactgg aacgtcctga gcttcaaatt ttacaatata acttttaaag
    61681 aaacttgata actccatcaa ggtatcatta tatgctattg aattagtatc caattttcta
    61741 ctcatcatta gtttataaaa atcttttagc ctaactaact cttcctctaa tatttcaatg
    61801 cctccaaggt acactttttt aacattctta gcagtcaact ccacaactct tttttctata
    61861 tctccaagct tatttatata tgcatcaata gcataccata ttgaaatcaa cagtttttcg
    61921 gcaacttctg tttttactga tgtgctttga ccatttgtat attttttaat caagtccata
    61981 agtattagag atacttcttg ttgtatatta tatacttctc tttcatctat cactttacaa
    62041 tttagacatt ccttaagtag agatatggaa tattggttct ttattaaatt attttcgttt
    62101 atattaatat tacttaaatt atttaacata caaaatctct cctatcatat attaaacttc
    62161 tccaaattta aatttctttg caaattcgtc tgcttctcct cttacattgt ccatattgcc
    62221 tgaaaatttt tcataaaatt cacccagtat ttctataatc tcatcatcac atatcttgtc
    62281 atcagtttca ttttttaaat aataaaaaat ttcttgcata tcattaatag cctctaaata
    62341 attgtccaca tttgtatatt gtgatgtata tatattttct attaactgtt ttgtaacttt
    62401 tatatctaat tctattcttc catacccctt taaagtatta tctctcgaat ttattatatc
    62461 ttttacatca gattcagaaa gagctagacc ataatctcca gattctatat tagtttcaag
    62521 cagttcattt ctttctattt cctttaaatt ctgatttata gaactcaaaa taataggtga
    62581 tatcattttt aaattctcct tttttatttt ttccattgac tttttttgtt ttttatgcta
    62641 tacttaaatt aatgtatatt attttaccaa ccacttataa tagtagtgtt aaaagtggtt
    62701 tttgtcaact caaaattact atctcaatta aacttttcaa ttttctcaac aaaaaaatac
    62761 catcatttag atatataatt ttctataaca acttttaatt cagtagttat ttactaaaat
    62821 ctaaacaatg atatatttat taattttatt tatctttttt ggctctactt ctacttttct
    62881 ttacatttga gcaatttcta caagaaggtg aacagtattg agatttagaa tttgtaggaa
    62941 tataaatttt accacagtac ttgcatttat ttaaagaaga aggttcactt gtaattgcaa
    63001 aggcatagat agtctcaata gctgttttca aagaatcaaa ctcccatgca ataattggtt
    63061 tatctaattg gcttatagaa aatcctatct tttgaggatt aaaccctcca gacataatag
    63121 taacactttc agttaataga ttagatgtat ttttatatac acaaatttga ttaaaatgct
    63181 tacacatatc tttagcaaaa cttacaatcc aatctagttg ttcagtgtag aactttgaaa
    63241 atactaaatc taaaatcaat ggtctctttc caaaaaactt tggagattct tctctctttg
    63301 atacatctat accccttcta tactttttaa aatacacatc ttcatcactt gcaaatggta
    63361 taaacatgtt tacatattca tctgtactca atatattctc ttttgtaata taattctttt
    63421 caatcatcag tactctttct tctccaacta tatctctatt atatacactt gaatatatta
    63481 aacccaataa tccatacttt tttacaaatt caagtacttc tttctttagt ttcatttctt
    63541 ttgtctcttt tgatatatct tgtaatgcct cttgtcctat gcgaattata tctactatta
    63601 tatcatctgc tacatcaaat gggttataca tggtaaacac agcatcttct gttggaacta
    63661 tatataattc atcttcttca gtaattttat attcataatc actataccta atccaatcac
    63721 ttgcaaaatt ccctattaat tctatttttt tattcataat aatcattcac acctttcaat
    63781 gtaatatata acttcatatt actattacac ttttagttta ttccatattt tctacactgt
    63841 caactattct ttttatattt ttagcatatt aaaatttata atagccttta taatggattt
    63901 ttacagctaa atttcttgtt tattgatgac taattcataa ttaaatttat aaaaactatt
    63961 tacatataaa attaatctct ttataattga tatgtaatat atttttacac ttacatatta
    64021 catatcaatt ataaagagag gtatctaaaa tcatggatag aaaacgtgaa ttaaaacaat
    64081 tatacaaaga aatgaaattt gacacaggtg tattcataat aaaaaatgat attactaaaa
    64141 agatttacct tggaaaaagt aatgacataa aaagcaaatt taactctctc aaatttcagc
    64201 ttggtgctgg ctcatgtatg ataaaagaat taaataatga atggaaaaaa tatggtgaaa
    64261 aagcatttac atttgaagtt ttagaactta taaaacatga tgataacaaa acagagaaag
    64321 actatttaga agaactagat attttagaga tggtttggtt agaaaaatta aaggaagata
    64381 atacttatga aatttattcc atataaaaaa taatataata taagaaaagt agatagtgtc
    64441 tcaaaataga catttagttc ataagatact tttttatata aaataaagta tcttttcata
    64501 attttaacaa tgaaaaagag gcttatctcc atttgatagc ctcttcccat atattttata
    64561 ccattataaa atgaacaatc tactaatttt caatgtatat attcatttta ctaataacac
    64621 tccattactt ctttacagca tccaaacatt gctctataat actcttatca cttataccta
    64681 ttgctgttac tttactagct ccacttaata tactcttatc acttttattt gaaactaaaa
    64741 caacaggagc attttttgca agtggtgatg caactaaagc ataaactaaa tcatctccac
    64801 ttgttatata gaactctttt gctccattat agaacttttc aataacattt ttattagttt
    64861 gatatctatc aacaccacca attctagttg ctctatatct gctcactatg taatcactta
    64921 atgtagactc tcctccaata gcatatactg gaacaggaga aactccaaac catgggtcta
    64981 agtctgtgtc ttcttctgct gaaggtatat cttttgtcaa tattatagga gctccatctc
    65041 tataagcaac agatgcaaca cttactgcat cagcttcatc cttaaatcca tttactaaaa
    65101 acatcttatc actgttttta attttttcta tttcacctgc aattttataa cttgtatcta
    65161 ctctatctac accatcaatt cttataactt gcattcttct cataagtaac attttttcta
    65221 catctttact tatagaattt tctccaccta ttacatatat cttagtaact ctattcagtc
    65281 tttgaagtgt tgcttctggt atatcatcct tattagttaa taaaatagct gcattattta
    65341 ctcctgcaag accacttgca gcaatcccat ctaccattgt agagtctgca ttgataagaa
    65401 ctgctgttgt aaaatcttgc ttatctgaaa taagcccagc tgtttcatat ttatctactc
    65461 cttgaatatt ttcaatctta tctagtgcgt ttattgatgt tggaaaacta acacttaaca
    65521 gtaatgctga aatacctaac gccaatacct ttttactaat cctcataaat tacctcccta
    65581 aaacaaatat atttagtatt agtataatat aaaatcattt aaaaatagtg taaaaatagt
    65641 tacacttttt tataatttaa ataattttag actaaacaca attcatccat taaaataact
    65701 tcatttattc tatatgctaa gccatcccac gttttttttg acatatctac agatgttttc
    65761 ttatttgagt tattcaataa agattgtatc ttagaatcta ttgcattata caaattattt
    65821 tcaaaatcat ataactcttc atcttttgga ataccttctt tctccataaa aggtagagaa
    65881 acatattcta tctttccaga attattaatc tcactaccaa tccactcttt aacaccaaga
    65941 atatcagtag tgattacatc tgtgccacaa gataaagctt ctaaaactac aactggtaat
    66001 ccctcataaa atgatggtaa cacaaatatt tgtgacctgt tgaatagctc agctaaatct
    66061 ctctgttcta actttcctag gaaattcatt ttaaatggag acttacttgc cagtttaact
    66121 atctcattat atgattcgat atcgcttcca gtacctgcaa aattgacttc tattaaatct
    66181 ttactatatt ttaatttaga tatagctttt ataaatggaa tcagtccctt tgatttacat
    66241 atcttacctg caaatactat ttttatttta tcatccttta ttttataatt tttattataa
    66301 aatatatcat cattataacc actaccaatt acaactactt tactttcact tactccaaaa
    66361 gtctttataa tatcatattt ctgattttca tgaagagcaa atattaaatc taatttcctt
    66421 atatttgcta ttatgtattc tttctctaaa tcaatggtat ttaactgtct taaacaagtt
    66481 ccatgacaaa tagacataac ctttatatct tttaccattt ccctaacaaa tgcagttaag
    66541 aggtacaaat gatgacatat tataagttct ggtttaaaat cattcatagc cttatctata
    66601 tttactttaa attgatattt caatctattt atcatgtcta tatttaaatc tttatatctt
    66661 gtactttcat atggcataga atcactcata cctacaacag gaaaatttaa ctccccacaa
    66721 ttatacttta ctggataaaa acttacttca cttggaaaac aatttacatc atcatttaca
    66781 tctatacctg caattacagc ttgcttatga ccgatttttt cgaacccttt tatcatacca
    66841 gacaaatata taccactacc tgtactattt ggtttttgtg ttattatatg aagaattttc
    66901 acttttcact tgcctccttt ctaaaattaa atagttttat acagtctaat cattatatat
    66961 atctaaatat aaacaagatg aatcatcttt tactttaaat cttggcactt taaccgcttt
    67021 atagtcatta tcttcaaaat cccttacttt attatgtata tatcctatac caaatttttc
    67081 tgctatacgt atcaattctt cttcttttat tagattatat ctatcacatg cacttgtaaa
    67141 accatcactc gttagcatca attgaaaatc tttttttatt tcaatgtatc catatataga
    67201 attttccaca gcttcctcat caaaatccaa tatccaatag ccctcttttg tatttttctt
    67261 caatctattg cttactattg tatccataac actagttcta atctcatcaa aagccatctc
    67321 ttccaagtta gaaagtttac tcatttcatc aaatacagta ttatcaaatt tacaaatact
    67381 cctatctttt ataactttgg aatctccatt tttaataaac aaagcacaat ctcctaataa
    67441 aaaatactct actttatttt catgaaattt tacaacaact atagaactag atggtaaatc
    67501 taatttttca accttaaacc catttaatct tagttcatac tcttttttta cttctattat
    67561 tccagtatta ataatactct ttaatgattc ttctttattt atatttttat ataaatacct
    67621 attccaccac tgaacatacc accttgcgtc actttcagtt gacactaaat tttttccatt
    67681 aagtcctgta gcaccatcta aaacccatgc cccaaatgga tttataccga ctacatcttc
    67741 attaaattta gctgttcctt gattacataa taggctatag tttcttatat ttaaagccat
    67801 atcaacctcc aaattgaata tctaaaaata aagttctatt taaaattata cagcaaataa
    67861 aaaaatctac aacaaaactt gttgtagatt tttacttaat ctatattatc tttatacttt
    67921 cagtatttta atgatggaat aatctatttt tagtaaatgc catgactatg ttatacttat
    67981 tacaagttaa tataacatta tcatcacgaa tagaaccacc tggttgtgct ataaaactta
    68041 ccccacttct ttttgcacgt tctatattat ctccaaatgg gaaaaatgca tctgaaccaa
    68101 gtgctactcc tgttaaagtt ttaagccatg ctctttttcc ttctccagtt agaggctctg
    68161 gtttttcttc aaaaaagttt tgccatatgc catcagcaag cacatccata taatcatcag
    68221 aaagatatac atcaatagtg ttatctctat ctggacgacc tatatccttt ttaaatttta
    68281 agtttaatac tttaggatgt tgacgaagat accaagtatc agctttgtta cctgcaagtc
    68341 tagtacaatg aatacgtgat tgttgacctg cacctacccc tattacttgt ccatctttag
    68401 cataacaaac agaatttgat tgtgtatatt ttaatgtaat aagagctata attaaatcac
    68461 gttttgcact atctgtaaaa attttattat cagttggaat atcttttaat aggtcttcat
    68521 ttattaatat ttcatttcta ccttgttcaa aagtaattcc ataaacatcc tttgtttcaa
    68581 taggttcagg agtataattt tcatctattt ttacaatatt atagttacct ttacgctttc
    68641 cttttaatat ttcaagggct tcatctgtat atcctggagc tattatacca tcagaaacct
    68701 ctcttgctat aatagttgca gtctccttat cacatacatc tgaaagtgct ataaaatcac
    68761 cataagaaga cattctatct gctcctcttg ccattgcata agcacaagct aatggagaaa
    68821 gctctaaatc atcaacaaaa tatatttgct ttaaagtatc tgataaaggt acccctactg
    68881 ctgctcctgc tggacttaca tgtttaaatg aagttgctgc tggaagacct gtagcttctt
    68941 ttaattcctt cacaagttgc caactattaa atgcatctaa aaaatttatg tatccaggtt
    69001 ttccatttaa tacctctata ggaagttctc cattcttcat ataaatcttt gatggttttt
    69061 gatttggatt acagccatac tttaattcta gttctcttgc catatactca tccctctcta
    69121 taataaatta atcataagtt tgattaatcc tatattaatt aaattattcg tactaataaa
    69181 attatatggc atatttatcc attaatcaac tatatttttt aaaactccta ttccttcgac
    69241 tttacattca actatatcgc catgctttaa atatacttga ggattcatcc ccatagcaac
    69301 ccctgctgga gttccagttg aaattatatc tcctggcttt agagtcattc ctcttgataa
    69361 atcatttatt atagtaggta tatcaaatat aaagtactct gtattagaat cttgtcttac
    69421 ttctccattt actacactac ttatatctaa ttttaaagga tgttcaaatt cttctttatg
    69481 tactatacaa ggtcccatag atgtatgtgt gtctaagctt tttcctctaa accattgaac
    69541 atgtttatct tgaagtgctc tttcacttat atcatttact attgtatatc caaatatata
    69601 ttcataagca tcttcttttg atatatttat accttcttta cctatgatta ctgcaagttc
    69661 tgattcatag tccaacttct ctaccaaatc tccatgtaag cttatcttat catccactcc
    69721 aattattttg tctgctctct tagaaaaata aattggataa tctggcataa ctacgttttt
    69781 tataactcca tctgggattt cattgacatg gtctttatag tttagaccta aacatataat
    69841 atctttttta ggtcttacaa ttggggaaca taatttaact tcttctaact tataacactt
    69901 tgcgttttca aatgaattgt tttttatttt ttctaaatct cctgtagata cgttttcaat
    69961 aaaatcattc atatcagtat ataatttact taatcctaaa ctattaattt catatatact
    70021 atttgtttct gaattaaata cacctatttt ttcttcattg ctactacaaa aagtcacaaa
    70081 tttcattttt attcctccat tcaataagtt gattaatatt atttaatttt tattagttta
    70141 tataaattgt aattcataat atttatatgt caatacatat ttatatattt taaaaatatt
    70201 caaataattt ttattaaatt tattagttat taatatataa gtgctttata aaacacaaat
    70261 aaaataaggt tgatttaaaa ttaaatttaa aacaacctta taaaccgatt atactatcta
    70321 cctaataaat atagcaaata agctcctcaa taatatacaa aaccctacat ctctaaacct
    70381 atacttaact aatccaagta caataccaaa aacagtacct atcataattt ttgaaataat
    70441 aacttcaaag gtgtagctcg aattgttata caatattaca taatttctta taacatctat
    70501 gtatcctata ttataaattc cagatagtat agatgttata cagataattt tactctttga
    70561 ctttataaaa ttacttagat agttccatat atattctcta aaaaataact cttcaaatat
    70621 tggaactatc aatacagaca aagtcatcat agttacatta aaaagtacat atcccttagt
    70681 acaataagtt acaattattg ctaaagataa aaccacaaca aaaagtatca gcttacactt
    70741 ttcaataagt atattgtttt tattttcttc aaaagcttct gtgatttttc tatttctaac
    70801 cttgttatac aaagaattat cttttaaaaa taaaattaac gataaaccaa ctaatgtaaa
    70861 agaaattaag tttataatat taaaattttc aagagtaaat tcaaattgac ttagaagtac
    70921 ataattcaaa atcatcctta atatttgaac tataaacatc aataaaatag aatctattat
    70981 gcattttttg taactatact tcatcccaat ttaaatcacc ccatgtatat gctaatcgta
    71041 aagtccattt aataccctac ttacagttgc tttgctccaa cttgtttgat ttgaaatttc
    71101 tttatagctt aagccatctc ttcttaaact ctttatatta tttatatcat catcagtaat
    71161 ttgtttttct tttggcttaa ggctattttt atagcttctt agtctatcca attctgattt
    71221 caaactatct acctcaaact gttttttttg aagtttactc tcataagaat ctctcatttc
    71281 attaaactct ttaatgtagt ttactttcca gtcctcatcc atttttgttt taaatatacc
    71341 catactttaa cctccttaaa ttttgttact caagttatgt atcgattata aacattaatt
    71401 tctatattta tctttaaaat ccttgtacat aacccctaga taagttagta aaattcagat
    71461 atatttttac aattttaagt atatattaac aatagaaaaa aatataatgt cttaatacaa
    71521 catattatat actaaaagtt gttaaaatga acctttttat agtctaaatc agagtcacta
    71581 tatgctttct tttcttcatc aggatatcct atagaaatta tacattctac actgtacttg
    71641 ctaggtactt ttaattcttc tctaatgtac ttatcagctt ctatattatc atcatgcatt
    71701 ctatttctta cttgtatcca acaagaacct aaacctagtt catgagcttg aagttgtatg
    71761 tatgaagcag ctatacttgc atcctctatc caaacatcat ttttttcttt atctgcaata
    71821 attacaatag ctaaaggtgc attttttaag aaaaatccac cacctttagt tctacattga
    71881 gataaattaa ttagcttttc tttatcatct accactataa attcccatgt tctaagcccc
    71941 tttgatgatg gagctaaaag agcagctttt aatattttat ctaatttttc tttttctact
    72001 tcaacatcct tgtattttct aatacttctt cttttcttta gaaatccaat catataaatc
    72061 atccctttca taatagcata tactaggtta tattatgccc ttactaatgc tgaaaatcta
    72121 ttatttaccc cttgtattgt aaatgctctt tataatattt tatcataaca gtagaaagat
    72181 ttctcctttc ctaaaaaact catttctccg atttttataa aaccacactt tgtaagtaat
    72241 aaattcattt ttgagtttat tgaatatgta tcgctcttta agtatgatac attgttttct
    72301 acagctaatt tttcagcaaa atcaactaac ttagatgcta ttcctgtctt tctaaagttt
    72361 ggatttacag ccattctatg tattaccatt gcttttttat tagatgacca atttaagcct
    72421 aaatattctt ctggctcttc ataattaaga catataaacc ctgctacttc tccatccact
    72481 tcataaatat ataaatcttg tttcttaata tctgaaacaa agtctttttc taatggatag
    72541 ttttcatccc attgtgtatt attataagtc ttcatttctt ccactgtaga ttttataatt
    72601 ttcataatgc tttctaaatc attcatattc gcttttctaa tcataaaaat atctccttaa
    72661 gttaatgtat ttatttacta tctctttact ttaaaccatt cattttctac gtttttgctc
    72721 attttttcta ataacttagt taccacttgt ttttcttcat ctgtaaaatt atcaaaacat
    72781 atctctatac ttctattctc ttcttcaatt atcaactcat aaacttccaa agatttatca
    72841 gttggagtta aattatatcc tcttttatca aactcatcct gctttttatc tacatatcct
    72901 gcctttatta atttttgtat agccttggtt gttgtagcct tgtctacctt taacatattt
    72961 gataattcca caagatttat accaggattt tcacagattc ttgtcaaaaa tgtaaattgt
    73021 cctttttgta actttaattc cttgtactta atatcattta ttgaatttac tgctctagat
    73081 aaagtaccta cttctcttaa tatattactg tctaaagtct taatcaaaca cacctccact
    73141 gaaactacta tggctaaagt caaatagttt ctgttttata gaatttcaca taatcaatat
    73201 attcattttt agttgaaagt tcaacttttt taaattttac catattttgg ttgaaagttc
    73261 aattaaaaat aataaattta tttaatcttt ctttgcatat taatcaatta attttaaaat
    73321 taaaatggat atcccaaaat taactttttc gtttatgagg aactctcttt tgtataaaat
    73381 caaatatatt ttatcattcc aataaaaaag gcttatctct attttgagaa agcctctttc
    73441 cttcaatcta tattttactt tttccctaaa taaaatctat acaatatact tacacacctc
    73501 atccgcaaac tctgtagtag aagctgagcc acccaaatct acagtcaatt tacttccttc
    73561 aagaaatact ttttctaaag ctgtttctat tttttgtgca ttttcatatt cacctaagta
    73621 tctaagcatc attactgatg attgaataag tgctgttgga ttagccttat tttgacctgc
    73681 tatttgtgga gcacttccat gaacagcttc aaatatcgca caatctttac caatatttgc
    73741 acttggaatt atacctaaac ctccaacaag cccagcacct aaatctgata gtatatctcc
    73801 ataaagattt ggcattacca ttacatcata attttctgga tttaaaacta agttcatagc
    73861 tgctgcatct acaatcaaat catcatattc tacaccatgt tttgatgcaa cttctctaaa
    73921 cacatctaaa aacaatccat cagacatttt cattatattt gccttatgta tagctgtaac
    73981 tttttttctc ttattatctt taacatagtt acatgcaaaa tcaacgattc tttcacttgc
    74041 acttcttgtt attatcttta tactttcagc tgcataatca cctattttat gttctattcc
    74101 agcatataaa tcttctgtat tttctcttac aaccactaaa tcaacatctt catatcttga
    74161 ttttatcccc ttaaaacttt taataggtct taaattgaca tacaaatcta atgcctgtct
    74221 taaagttaca tttacactcc taaatccttt acctacagga gtagtaattg ggccttttat
    74281 agctattttg ttctttttta tactatctat aatatattca ggaagtggag taccatactc
    74341 ttcaataact gcctctcctg cattaacttc ttcccattct atttctactc cagtagcttc
    74401 tactaccttt ttcatagctt tcgcaacttc tggtcctatt ccatctcctg gtataagtgt
    74461 cactttatac attcaatatt ccctcttttc atattaatta gcttgatttt tagtgtagtt
    74521 taattttcca ccagctttta atacatcaac ttcttttgct gacaattcta ctttgacctt
    74581 aaaagaagtt cctttagttg tattcttaac ttctaaaatt ccactaccta gattgtctaa
    74641 aatatttggt atctccagat tatctaaaag agatatattt tcataatctt tctcatcaca
    74701 aaactccatt ggaattatac cactatttat caagttagcc ttgtggattc ttgcaaagct
    74761 cttaactatt acccctttaa cacctagata taatggtgct aaagctgcat gttctctact
    74821 tgaaccttga ccataattat ctccaccaac tataaatcca ccattattgt cttttgctct
    74881 ctgaggaaat tctgtatcta cagtattgaa acaatagttt gcaagatacg gtatattact
    74941 tctaaaagga agtaacttag catttgatgg cattatatgg tcagtagtta tattatcttc
    75001 tgtctttaat ataacttttc cacctataga ctgacttagc tctgtattaa gagggaaagg
    75061 ttttatatta ggtcctctaa ctacttctac atcacttcct acatcagcag gtttaattat
    75121 catgctatca tctatcaaaa actcatttac atctaaattt gtaaatttaa tatcaaattc
    75181 tcttgggtct gtaagcactc ccttgattgc acttactgct gccacttctg gacttaccaa
    75241 atatacttgt gctgacaaag tcccacttct accatagaaa tttctattga aagttcttaa
    75301 agacacagag tcagtacctg gagattgacc cataccaata catggaccac aagaattttc
    75361 tagtattcta gctccagcac ttattatatc tgccaaagcc ccatttctag caatcatctc
    75421 cataacttgt cttgaacctg gtgctattac caaactcaca tccttatgta ctttatttcc
    75481 tttcaggatt tgtgctactt tcattaagtc ttcataagaa gaatttgtac aacttcctat
    75541 tgccacttgg tctattttaa tcttgcctat attttcaact tcatctacat tgtctgggct
    75601 atgaggtttt gcagctaatg gttttaattc atccaagttt atagtaatct cttcatcata
    75661 aactgcatct gcatctggtt ttagctctac ccatgcgtct tctcttcctt gactcttaaa
    75721 aaattctagt gttttttcat cacttgggaa gattgaagta gttgctccaa gttcagcccc
    75781 catatttgtt attgtagctc tttgtggaac agataggctt ttgacacctt ctccaccata
    75841 ttcataaact ttacctactc caccttttac agtttgtttt cttaacactt ctaatattat
    75901 atcttttgat gataccatat tatttaattt tccaactaga ttcaccttac agacttttgg
    75961 tgcttttata tagtatgctc ctcctgccat ggctaaagca acatctaatc caccagctcc
    76021 aatagccatc atgcccacac ctccagcagt aggtgtgtgg ctatcagaac ctaaaagtgt
    76081 atctcctggt gttgaaaatc tttctaaaaa tacttgatga caaataccat ttcctggctt
    76141 agagaaataa actccatatt tatctgccac tgtttgtata tacttatggt cgtctgcatt
    76201 ttcaaatcct tgttgtaaca tattatggtc tacaaatgcc acacttcttt tagtctttac
    76261 tttatctatt cccatagctt ctagttgaag atatgtcatt gttccagtag aatcttgtgt
    76321 taaagtttgg tctattttta taccaattga acttccagca acagcttctc catctactat
    76381 atgtttttta attattttat aaactatatt atctcccata ttttcctcct aaacaattat
    76441 atcttaaata tatgaacctc taactgcttc ttcttctgtt gtgcctttct catgtgctag
    76501 tatatcacaa tataattgaa gaatttcttt atccattaaa cttcttttta atcttataga
    76561 tgtagctctt atagcattta atagcttggt agcgttttct ggagaaatat acatttcata
    76621 ttcactcaac ttatttacaa ctgcagctct tcctgaatgt ttacctatta ctatttttct
    76681 ttcaagattt acttcacttg ggtcaaatgg ttcatagtta tgtgggtctt ttaaagctcc
    76741 atctgcatgt ataccagatt catgtataaa catattatcc ccaactactg gtttccatgt
    76801 aggaagtatt cttcctgatg cctgtgctac atactcacat attcctctaa attttctagt
    76861 atctatatta tttaaatcac atttataaac acacttaagt gccattaaaa cttcttctaa
    76921 tgctgcattt cctgctcttt cacctaatcc atttactgta acaccaacat aatttgctcc
    76981 tgctgctatt cctgcaagtg catttgcagt tgccatccca aagtcattat gtgtatgcat
    77041 ttctatatca aaattagttc tttcataaag agtttctatt gcattcttta tagaaaaagg
    77101 attcataact cctactgtat cacagtatct aaatctatct gcccctgctt gttttccaac
    77161 atttataaat tcagttaaga agtctatatc tgctcttgaa gcatcttctc catttactga
    77221 aacatataat ccatttttct ttgcaaattc aactgtttta gccatatttt ctaaaaccca
    77281 gcctctagaa gttctcaatt tattttctat atgaatgtca gatactgata ttgatatagc
    77341 tactgcatca acaccacaag aaatagattc ttcaacatct tttattactg ctctattcca
    77401 agccattata tctgatttta aatttctact acatatgtgc tttattacat ttttttcatc
    77461 tccacccata gtaggtatac caacttcaat ttggtcaaca cctaggtcac ttaacatttc
    77521 agcaatcatt attttttctc tatttgcaaa tacaacccca gctgtttgct ctccatctct
    77581 taaagtagta tctactattt ttatttcctt tgctctatct tttgatataa cgcacatatt
    77641 aatgcccccc ttagtatact tttaatttta aaaacattaa gtcttatttt tcattgatac
    77701 ctctaactta tgattatttt tttatttttt attcatttta atttcatttg caatttattt
    77761 ttttagcttt tcatatcttg taatctatta tattactttg tatcatttat tgcactatat
    77821 tttttctttt ttgtgaaaac ttcttaaaaa tgaaagttat tatgtttttc ttgcatttta
    77881 atttaatttt taaatagatt tattttcaaa aaacctttaa aaataaacct ataaaattcc
    77941 tactaaaatt taatttaagt tacattccat tttaaagtat cttaatatat ttttaagcta
    78001 tataaataat aattaaaaaa tttactaaaa atacttacaa atatgatatt attaattggt
    78061 taataaaaaa gaaaattttt catgaaaggt aagataacaa tggatttcaa aagcttaggg
    78121 attagtgaaa atacaataaa tattctaaaa aaatcaggaa taacaacacc tacacctata
    78181 caaaaagaaa gtattaaact aataaaagaa ggaaaagatg taatagcaga agctcaaact
    78241 ggaacaggaa aaacactagc ttttttactt ccgatatttg aaaatatatc attagatata
    78301 aatgatatac aagtacttat actttctcct acaagagaac tagctattca aataacagaa
    78361 gaagctatga aacttaaaga atctaaagat gtaagtattc ttgcagcata tggaggaaaa
    78421 gatattggtt ctcaaataaa gaaactaaaa ggaaatattc atatgattat agctacacca
    78481 ggtaggcttt tagaccatct aaatagaaaa acaatagacc ttagtaagtt gaagactttt
    78541 gttttagatg aagcagacca aatgttgctt atgggattta aaaatgaagt ggaagctatt
    78601 ttaaaagaga cttcaaacaa aaagcaaaca ctatgctttt ctgcaactat aaattctcaa
    78661 gtaaaaaaat tagcttatag atacacaaaa aatcctgttg tagtttctat tcaaaaagaa
    78721 gaaatcactc ttaataatat aaaacaagaa gtagtagaaa ctacagatag aaaaaaatta
    78781 gatgccttat gtaaggtact agatgaagat aatcctttta tggcaataat attttgtagg
    78841 actaagagaa gggttgacaa tcttgaagaa gctcttgcta taagaggata taattgtcaa
    78901 aaacttcata gtgatattgc tcaatcaaaa cgagaaagaa taatgaaatc atttagaaat
    78961 ttagatatac aatacttaat agctacagat gtagcttctc gtgggcttga tatatctgga
    79021 gtaagtcata tatataatta cgatttacca gaaacaccag aagactacat ccaccgtatt
    79081 ggtagaactg gtagagctgg tgaagaagga tatacatgtg cttttattga ccctaaaaat
    79141 gaacgaatgt taagtgaaat agagacggct atagaatcta aaattagtag aagaattata
    79201 gaattataat ttatagattg cttaaaatac caatgccaca caaacactgt aatatataga
    79261 aagctacaga aaacatgtat caatctatac tttgctgtta tactatttta tattaaagaa
    79321 aaaagaggct atccaaagta ggattagtct cttttattgt caaaataatg aaaatatatt
    79381 tgacttcata taaaaaagag tgccttataa actaaaagtc cattttgaga caccctcttt
    79441 ttatctttta ttcttagttt tatattgctt gtttatagtt gtttaatatt agattttgca
    79501 aataatctta ataaacatgc agatatatta tctatagtat ccttatctat agtattctct
    79561 ttagcaatat tttttgctac tacatctaat ttacattttc atttaattcc gctggccatt
    79621 tagcttctgg attttccttt gcaaacttct tattcttata atgtcctagt gtaaggaatg
    79681 gaattactat agtgaataga ccaagataac cacaatatcc atatccatat ttaacaatat
    79741 tacttaatcc tgtaagtgat ataagcattg acactaccat tattgcacaa gctgtaaata
    79801 cccttctttt cattcttgaa gaaaggaaag aaagtgcttt atggtcttca aatctattta
    79861 caagaccaaa tatagtagtt actcctgtag acattaaaca aaggaataat gcaacattat
    79921 aaattatgta tatagtatga tttccagatt gacctgcaac ataaagagta gggagtgttg
    79981 tttgcccagc agcaataatt tctctatacc atcccattag catagttaca gcaagtccta
    80041 atgcaattgc attcataaca aatgaaatta tcattgcctt agtagcttct tttgagttct
    80101 taagaagtgg tcttgaacat cctgcaagtg taggtataac aaccgattga aaacctgcat
    80161 aaataaaagt attaagtatt ggcttgatat agccaggtgt gaaactcgtt ctatttgata
    80221 atatttcagt tatttctggt actttagctt ttataccaac aataaaaata gtaagagtac
    80281 atactagaat agctattgtc attgctgtag ctgctttaga tacaagcata gcaccaaata
    80341 tagtaaagac aagaagtaca actccaataa taaatacagc tacaaaataa tttactccta
    80401 tactttgaaa tactgctgct gcacctgcta taacagcact tacagctatt aaaaccatta
    80461 gatagtaata tatctcccat attatttcaa gttttggata tggtctccaa agctcacaaa
    80521 ataaatcctt ataattccta caattgttat tattatacat tatgataact tctctcatgg
    80581 tagcagtaag tataatcatt gctaaaattg ccataagtgg tgctgtccat ccatactgca
    80641 catagtactg agtttcttga ttccctgtag caaatcctcc tcctgcatgt gaactaaaaa
    80701 gaacgcttgc aacaccaaaa atagctaaca tagagcccgt tacttttgct ttctttacac
    80761 ttttttgcat gaaatcatcc tccctaaaat gatattgaaa gtttttattt taacacttta
    80821 ttgataaaac aataacattt ttgctcatta aattcaacta tatttttcca atgactttac
    80881 attttcaact tatttccacc tttatattaa atatttttta tatatttatt ttatttttta
    80941 aatagtattc aaattcactt tgttttttaa ttttatgaaa tatctttttt aatgttaaat
    81001 attatacatt ttttctttat tattatataa ttttttcttt attattatat aataataatc
    81061 gtatagtata aaattccttc ttttattaca ttcattggaa ttatcaaact ttaaaagaat
    81121 aaatcaatat attttgtgaa aaaatatact gtaatgtaag taactttgat ttatttatat
    81181 ttattctaac attattaata cataataaaa ttgtttatta atgaaaatat attctcatta
    81241 aaaataaatt tttttacaat atttcatata aaagtatatt gatttctctt aaaataaacg
    81301 taacaaaaaa gatattttct atagaaaata tctttttaac cttcaactta aatcttatat
    81361 actttcaaat actatatact tatggtcagc cctactccaa cttcatttat attcaatatt
    81421 tcattcatct tcgcttttac cttaaaagaa acacagtgac aagggtacaa cattctcatt
    81481 tcttctttat ccaaatattg tattgtacta tctaacctat tattcaattc aaaaagatga
    81541 aaaccaccta gtataccaat aactctatca tctccacata cctttttagc atactctact
    81601 atattacaaa ttccactatg agaacatcct gtaacaataa aaataccttt atcagtttta
    81661 caaactatag cagaatcatc taaaacataa tcatcttccc acaaatctcc tattttacat
    81721 ttaccaattt tagctctttt ttcaaaatca tttatagaag gtatttcacc taaaaacaca
    81781 caattcttac ttagattaaa tggcttatcc ttaggattat acataaaaat atttttaatt
    81841 tcctcagcag aaaatggagc tcctatgctt ttctctccat gttttctagg tataaaacag
    81901 ttaggatgtg aaataagttc aactgtagat aaatcatacc tattttctag aaactggata
    81961 cctcttgtat ggtcattatg cccatgagaa aaaacaacat gagttaaatt tcctaaatct
    82021 atatttaatt tttcagcgtt tgatatgaat acatctgaat accctgagtc aaacaaaatc
    82081 ctatttccat caatctcaat ataatagctt actgctggtt ctccaacaaa gtatctatca
    82141 atataagtat tattgtcaac taaaacttgt atcttcaatc tttccataat aatcactcct
    82201 taaattttta tttactttaa agtacagaat ctttagttta atagtacgac atcacagaat
    82261 attttacaat ttaatatctt taattttcat aaatagaagg agtctatctc aaaataaaga
    82321 gataagattc tttttcattg ctaaaatgat aaatatattt ggcttcataa aaaaaagagt
    82381 gacttatgaa ctaaaaagtt cattttaaga cactctcttt tataaaatat atttatcatt
    82441 tacttttata gctatctaaa atctaatagt ttcaaacttc aatctataca tgctgtatgt
    82501 ttgtataatt tgatatttca gagttaacag tatataaatc atcaacactt aaatcatgta
    82561 tatctttatg accagaaatt ctagcaaaag tcttaagttc ttctaaactt acatttaaaa
    82621 agtttgccac tctattagca ctgttttcta tatgtaatct ttttctcaat tcctcatcct
    82681 gagtagctac tcctacagga cacttaccag aaccacatat acgatattgt tgacacgccg
    82741 ctgccataag agcagaactt gcaatagcaa ctgcatcagc acccatagca attgccttag
    82801 caaaatcagt agatatacga agcccacctg ttataaccaa atctatatct aatccatgtg
    82861 tatctatgta ttttctagca cgataaagag caaatattgt tggaattgaa gttgcatctt
    82921 taagcaactt tggacttgct ccagtagctc caccacgacc atcaatagtt acaaaatcag
    82981 gtttagcata agctataaat tccatatctt tttcaatatg acctgctgaa attttaacac
    83041 ctattggacg cccttctgaa acttctctaa gttcatctac aagtttcttt aaatcttctt
    83101 tggattgtat ttcctcaaaa caagatggac ttattacatc ttgacctaca ggcttatttc
    83161 ttacttttgc tatttcttca gttacttttt cgccaggaag atgacctccc ataccaggtt
    83221 ttgttccttg accaattttt atctctatag catcagaatt tttaagattt tcttcagtta
    83281 cactatattt atttggtaca tactcaaaaa tatacttgta tgaagcttcc ttctcttctg
    83341 gtaatatacc tccttcacca ctacacatag ctgtcttatt ttgggctgca ccctttgcta
    83401 aagctatttt tagttcttta gacaaagctc caaatgacat gtgggaaata taaactggat
    83461 tttctataat cataggtttc tttgcttttt ttcctattat tgttgttgta tttacttcat
    83521 catgctcatt taaaggtaat ggatttaatt gagcacccat aattaaaata tcatcccaag
    83581 aaattactgg tagtttagtt ctcataggtt ctattataga ttttcctgta acagccattt
    83641 cgtgaattat atccatatgt ttctcaactt catcatctct tcttaaatat gtacttaagt
    83701 aatttaaatc tccctctttt tcagtattta atttagattc atcttcaact atgtcttctg
    83761 ctatcttttc atcttcttca tagtaaacag tacttatctt tccaaaataa ctacgacctt
    83821 ttgtacatac agggcattcc caatcttcac ttaattcatc ccatgtttta tcattcttag
    83881 attcatcata aatatatcca caaacactac atttataaat tgacatatta ttttctcctt
    83941 atattatatt gacattaaac aaaattaaaa cttgaattta tataaattta taggaggcta
    84001 tttgtatgaa aatacattta tagcctcctt tttgactcaa tttatttaaa tattacagtt
    84061 cagccttcca taatccatgt aaattacagt aagcataggc agaaatcact ttatcatcat
    84121 cattcaaagc aaatttaact acaggttctc catctactgc tagacatttg cgttgaccac
    84181 cttgttcagt cataagatac acccatgcta tatgatgttc tttagtcatt ggatgagttg
    84241 tgctacttac tttaacagta acattatttc catccacttc aattacaggt acatgttttt
    84301 caactgctgc atctgttgta ttaggaacaa gttccttcat aggttttcca caacagaaaa
    84361 taggtacacc accactttgt atcattccta caaggtttcc acaagtctca catataaaaa
    84421 atttttgttc actacacata aactcacctc attaattatt tttagaattt gaaaactaac
    84481 ctacttggct acacctttta caattattac aaatcccttt aaaacttatg ttataagatg
    84541 ttatttttat gtctgtctcc tcagatatta attcttgtaa attattaaga acttcggatt
    84601 ctaaatcgta tacctctcca catacttcac atatgatatg atagtgatta tctattcgac
    84661 catcaaatct atctggatac cctggaatac taacctttct tataaagcca tgttccgtta
    84721 gctgagctaa atttctatac acagttccta agcttaaatt tggattatct ttttttaagt
    84781 tttcatatag gtaatccgca gtaggatgaa ccggattatt taatatttca tttaaaatca
    84841 gttctcgttg tttagaaaat ttcatagtta acattccttt ttaataatga taatttttaa
    84901 taattttcag cttttatatt gaaatacgct tttggatggt cacatactgg gcatttttct
    84961 ggtgcttcag tacctacata cacatgacca cagttttgac attgccaaac aacttcttca
    85021 tctcttttaa atatttttcc ttcatttaag ttttctaaaa gctttaagta tctttcttca
    85081 tgctctttct ctatttttcc aacagcttca aataaataag ctatcttgtc aaatccttct
    85141 tctctagctt ctttagcaaa ttttgcatac atatcagtcc attcatagtt ttcacctgct
    85201 gctgcatcct ttaaattttc ctctgttgaa ggcataccat catgtaaaag tttaaaccat
    85261 aatttagcat gttccttttc attgttagca gtttcttcaa atatagcagc tatttgatta
    85321 taaccttctt ttcttgcttt tgaagcgtag tatgtatatt tatttcttgc ttctgactct
    85381 cctgcaaatc ctgccattaa attcttttct gttttagttc cttttaagtt cataattaat
    85441 tcctcccttt ttaataatag taatgattac tatttctata tttatatagt atctcatttg
    85501 ccaatttttg tcaactatat ataatattat tttttttatt taaatattcc tattttcaaa
    85561 tatattattt aaaacatata ttttagaata tacttaatgt aatatataaa acacatatga
    85621 cagtactctc tcttgtcgct atacctattg caagtattat gatagtcgtg atttaataaa
    85681 tacaaaaaga agctacagtt atgaaaaatc aaaactgtag cttcttgaat acatgagcat
    85741 atagacactg tacgacagat tttttctttt cactgtctag caacttaaat aatagaaaca
    85801 atatttatgt tatttatgag aatacttttt atgctttatc ccttttttct tagatatggt
    85861 cataacttta tcataattag gtgtaaatac aagtagaata gttgtcaaga ttagaattac
    85921 aatcaaagtc atagcaccga taagtggctg ataaacagta ccagcaccat tgttgtatcc
    85981 aactagacca agacctgctg tgattggata aaagtctgtc agatttcttc cagcaacaaa
    86041 cacaccacaa aaaccgtata caaatgcaat ccctacaccc gtcagaaatg cattttgttt
    86101 acgaccaaaa taagcaataa tcggcaaaac agcaacataa caatacagat taacagacaa
    86161 aatctgaact aaggatttta caacgagtgt aacagatata ttgatattgc aaaacaacaa
    86221 ccccaaaata aatgtgcata agaagctgaa aagacttaac aatacagtaa ttcctccaac
    86281 cgcaattaat tttcccacta gcaatttgcg taatgaaata ggaacagtta ggatgttttt
    86341 taaggtttgg tctgtatatt cacggttaat aagatatcct ccaataagtg taatcccaaa
    86401 tggaaaacta agactgaaat tattccagat aactccgttt gcaaagctct catacgttag
    86461 agggtcactg ccgtgtgaac ttacaacctg aaaaactgcc aatagtgctg aaaacagaac
    86521 agcaacaaca ccaatccata gaatattata tctttttatt ttttgaaatt ctgtagtaat
    86581 tatatcaagc atagatacct cctaattctc ctgctttttg tatatcatac aaatcagcag
    86641 gactgctata atggttatca aacataaaat acctacacaa gcaggagttg agagcaaata
    86701 tggctgtcta agtgccgtgt attcgccagt gggatctccc caaaatgcca tccaccaacg
    86761 cattataaca ggagcaggta atacacttaa tattgggtta tttggttcaa aattgataat
    86821 atttaaggat atactaaaat tgaaaatagc atatacaaaa gaaagtataa tagaaaaaat
    86881 atagctgcga ttgaaatata caatgagtac cacaacagga agtacagtaa caaaaaacat
    86941 aattccaaaa gcaatgctca ttcctaattt tacagcaacc ccctctacta ttccaacaat
    87001 gaaacctcca atgatagtag ctcctaaccc tgcaacagag tagaacaatg atataaacag
    87061 caacacagcc aattttgcca gagccagttt tcctttttgc actggcactg ttgcaagatt
    87121 ttttaataca tcattatctc tttctataaa aaatagttgg ctagcaacaa tacttaatac
    87181 aattggtaat agcaaaaaat atccaaaatt gacaactaat ttgaacaatt gctcaaaggg
    87241 caagttgtcc tttgcaatca aaattgttgc gggaattgga aataagcaag cacctaaaat
    87301 agaaatcagt ataaatttta accgcttgag ttttgaaaat tcacatgaaa ttatatcaag
    87361 caattccttc accccctgtt actttcttga agtaatcttc aagagtatct tcgcataaat
    87421 gagattctga tacctcaatg ttgtttagaa tgaaagcacg atttatttct gcaacagaaa
    87481 catctgtatc atatagcata atattgtaat tatctgctac tttgaaattt ttcaggttaa
    87541 gttgggtttc cagaagcctt gctgcctgtg ctgcatcaga tacagcaaaa tgtatgtatt
    87601 tactgttttt ttcttctaat tgggcaagac tttcttcctc caacaaaata ccatggtcaa
    87661 taatgccaat gtcatctgcc aacaaggcaa tttcagaaag aatgtgactg gaaatcaaaa
    87721 tagttttacc tcgttctgtg cagagatcac gaataaacgt tcttacttct gcaataccaa
    87781 taggatcaag tccattgata ggctcgtcca aaatcaacag ttgtgggtca tgcataatgg
    87841 caagagcaat cgccaacctc tgtttcatac caagagagta ttgagaaaat aactttttgt
    87901 cattgtttgg caaaccgact acatccagtg ctgattctac tgcatttttt tttggtattc
    87961 ctctaagcct tgcaaagatt ttgagatttt ctgttcctgt cagattagga taaaaccctg
    88021 gtgattcaat caaacatcca attcgaggaa gaagcttctt ctcgttattg tgaatgtcct
    88081 gaccaaatat tttaatttct ccagtagttg gttttgttag acccaataac attttcatag
    88141 ttgtcgtctt acccgcaccg tttcttccta gcaatccgta aatgcgacct ttctgaacgt
    88201 gaatattcaa attagaaacg ctcttttgag caccatattg cttagtgaga ttttttgttt
    88261 caataattaa attattcata aataataaaa gcctcctttg tttattaaag ttatcatacc
    88321 acctcaatct tacattaacc ttgcaacaac cttgtattaa ccttgcaact ttataactta
    88381 caaaaaatcc ccctgtgtat acatgtcaca tgggggaaaa acaattttat attaatggta
    88441 agctcactgt aaatacggta tactttccaa tctcactttc tacggaaacc tgaccaccca
    88501 ttcgctccac catttgactg acaatagata gaccaagacc acttcctttt tctgaacgtc
    88561 ctttatcaca cttatacagt cgctcaaaaa tatgtggtaa attttctctg gcaatcccaa
    88621 caccatcatc ctcaacacgg agtaatacca ttctggaatc ctcactcatg gtaatcttga
    88681 tttgccgagc cttactgtga gcaagaacat tttgaaccag attattgacc acacgggaat
    88741 atccatctgg gtcgaggttt accattagtc gattttctgg aatatcaatt tcaaaattca
    88801 gtttcttttc atggaatata ggaatccagt ctttcaaaat attgcgtgac aactctgcaa
    88861 tttccacaga ttctattgac agcgtaaatt catcagagtt caaccgaaac cagtcaaaaa
    88921 gaacatcaat gtaatccttg aggtcgtagg ctctacgcct agcgatttca aggtattcct
    88981 cccgctcttg tccgataact ataccactgt gtacagcatc catataacca atcagagttg
    89041 ttaatggtgt acgaacatca tgagataagc ttgtcataag ttgtttgcta gctttatccg
    89101 actttttcag agaaagtaac ttattttcat aatcgtagac aatctcatta agctgataaa
    89161 ccaatggagc cataacatca catggcttaa ttagtatttt acgattttcg tctccaattt
    89221 gtacatcagc cagtatctcc tctatatctt ttaggcgctt gtaaatatgc ccaagcttgg
    89281 aaaaagcaaa tatggaaaga aaaagtagac caatcgacag caagagtaag aaaagaatta
    89341 tcgtttgttc gtccattttc atacctccgt gttgaattga tacccaattc cttttattgt
    89401 ttgcaaatag atgggagatg atgggtctag ttcaattttt tttcttaggc gactgataat
    89461 agccatgata ttgctgtcat catatacata tggctcaccc cacacggctt cataaatctg
    89521 ctgttttgtc aaaatcttac cctgatgcct tgcacagtaa agaagtacac caaattcctt
    89581 gggtggaagc aacataggtt cgccattggt agtaactgta tgctggtcaa ggtcaatcaa
    89641 caaacctttg aaagaaagtt gctgtggctc ctcatttttt ggattaaaac gggtgtaacg
    89701 tcggattaaa gacagtacac gagcagtaaa ttctgtaatt tcaaatggtt tggttagata
    89761 gtcatctgca ccagctcgca atccatgcac tttgctgtaa ttatcgcttt ttgatgtcag
    89821 cattaagatg ggaatactgc tatattttcg tatttgttcc atagtttcaa aaccatccat
    89881 acctggcatc atcacgtcta gaactactaa ctgataatct tgttttgaaa gttcaaccag
    89941 tccatctctc ccagaatggc aatagtttgc ttcaatctgt tcaattgaga tactcttttt
    90001 taacaaaata caaagatctt tatcatcatc tataattaaa actttattca tcttagttcc
    90061 cctttctaca ctcattcgta gactttttta tcactaggaa tttagtcata ttgtagtatc
    90121 ttgacatcac ttagaatatg ctcctcaatg aaatagtagt ttatcatatg aggatttata
    90181 tctcatttat cacttacttc ttcaagtgta atgctattct tatacctata acacccatta
    90241 gtatatttca tcattgtgaa aaaatcaagc atattataag tgtgcttgaa taaaacaaac
    90301 atgataatac atttactata tacagagttg aagaatttat taaatcaaaa catcacaata
    90361 aaacatatgt gaaataagca attattccag aaaatatttt aaagtatctt tggaactatt
    90421 cctataagtc cagaataaat ttagggttaa ctcaatggtt tatttcaatt aacatactgc
    90481 aaaaaatggt gggtttgcat gttgagaaat gtaaaaagta gatatacatc taaagtacag
    90541 gcgtataaac attaaagttg taatgatata aaggtttaaa aaaggagttg agcttcaaat
    90601 ttaattaaaa aaatcaattt taagacaacc cccttaagta atgcaattat tcatatttaa
    90661 agtgtagtta atttttaatt ttttataata ttactagcat attaagatat tctaactatt
    90721 ttcgcataat tctcctaaaa tcttatgaat atgaatcatc aaatataact cctcttgtct
    90781 tggtaattct ctggagtatt ccttatacat ataagctcct acctttttca cacattcata
    90841 ctcttcctta caattttttt gaacttgctc atatataaaa tctatttttt ctcttgatgg
    90901 ttcattagcc agaaatcttt gtgaaaaggc ctttagatgc attacaaatc tcctataata
    90961 aaatgactct ttattatata caatagaaaa gtgataatga actatttgca aaatagcatt
    91021 tacaatttta gcacttctct tatttctatc actataagga ttatcttgtt gtgcatttat
    91081 aaaatggcct gctatattac caatctcttc ttctgatagg tctaaaccaa gaacctcctt
    91141 aaaaacagta atagcatatt ttcctatatc atactctttt ggattaaatt ccttgatttc
    91201 gaacaaatag tgattttcaa tcattatacc ttctttaaaa cgtctcactg caaaggcaat
    91261 gtggtcagtt aaggccaaat atatatggtt cataagtttt aagttatatt tttctattcc
    91321 atatgcaatt atcatttgag ctataccaaa atattctgca tctatttctg ttgccaattg
    91381 tataatactc ttttttatat tttcatcatg aagaacaaaa atcttttcta tatctttttt
    91441 atttaactca gacccggcct tataattatg gccaatgcct ttccccatca atattatttc
    91501 ttcatcatta tcatcctttg caagtagcaa cgaattattt aatacctttg taatgtacat
    91561 actaaaaccc tcaatatata tttatgttta ttttactatt ccattgttct ctataacttc
    91621 tttataccag taaaaactat ctttcttgat tctttttaaa tctaaaactt catggtcagt
    91681 tctatttata taaacaagtc cataacgctt attaaaacct tgagaagaac ttaaaaggtc
    91741 tgtaaatgac catggacaat atccaatcat ctctacacca tcttcaatag ctagtttaca
    91801 tgcatttata tgacttctta aatagtctat acgatagtca tcatgaattt ttccatcttc
    91861 taatatatct ttagctccta gaccattttc tgttattata acaggtaagt gatatctttg
    91921 ccaatattca tttaaggcaa ctctaagacc tgatgggtct attgctgctc catactcaga
    91981 agcctctaag ttaggattca ttgacatttt aaatagtcca tacatactaa aatcaacagt
    92041 tccttctctt aatccaaatg gatgttgtga atcttcaggt aaagcttctg cacaatttgt
    92101 cctataataa tttacagcta taaaatccat tttagctttt ttaagtatct ctttatcccc
    92161 atcttccatg tgaggaacta tatttctttt ttcaagatac ttcatataat accctggata
    92221 ttctccataa tgatgcatat caagcatata gtacacttta aaattatcat tcattctagc
    92281 tgcatataca tcttctggct tagaagtaag aggatatgtt acagatgatg atactgctgc
    92341 tccaatttta ctttctttta tcatctcatg acatgcattg actgctaatg catgtgctaa
    92401 acaaagatta taatccatct gagcacgcat tttatctatc ttccatgaat ctgtttcatc
    92461 atatatatta attctctcct ccactctaac aattaaattc tgttcattat gaggttgcca
    92521 atactttacc ctatctccaa aatgcttaaa gcatatttta gcaaatcttt caaaagcata
    92581 gacagtttct ctactttccc aaccattata tttctctact aatttaaatg gaaggtcaaa
    92641 atggtataaa gttacgaatg gctcaatatc acactctatc agtttgtcta ttatcttatt
    92701 ataaaattct aaacctttct ggtttatctc tccttcacca tctggtatta ttcttgccca
    92761 tgaaattgaa aaacgatatg ttttcatccc taattctttc attaattcaa tatcttcttc
    92821 ataattatgg taaaagtctg atgcgacttt agtatctgcc tgtaaatgag actttttaaa
    92881 agaattatag tcggctacgg tttttccttt attgtcttta tcccaagctc cttccacttg
    92941 aaatgcagaa gatgatgctc cccataaaaa gtcttttgga aatcctgtat tcataaatat
    93001 ttctcctttt tatattgatt attttctttg ttgattcatt gcaataagtt cactctatat
    93061 taactctttt ctttgttatt tcattgagat agatttaccc tatattaatt attttcttta
    93121 acaattcatt acaataaact tactctatat taattatttt ctttgttact tcattgcaat
    93181 agctttactc catattaatt attttcttta acaattcatt gcaataaact tacttttaga
    93241 tgtatttaat tgttgattta cttatttcct tttaaatcaa tttacttatc tctagtcaaa
    93301 ttaacttaat taccagctaa tactaatgaa attatattat cattggttga aacataacta
    93361 gatttacaag aaactacttg cccaaactga acctcccatg actaaagtca cagggttcct
    93421 gcttcataga attttgcata ctaaaatatg tcttactaat tctccacagg ctatccccgt
    93481 agttcctacg gttcttacat aagttattta ttttgaattg ttattagtct taatccttct
    93541 tttaatatat ttatacttgc atttatatct ctatcgtgag tttcattaca actaggacaa
    93601 atccattctc ttatatttaa gtccttcact tcctcgtttt tatacccaca tttattgcat
    93661 atttgtgaac ttgcaaagaa tttacctacc tttacaattt gtctaccatg ccaattagcc
    93721 ttgtattcta attgacgaat aaactctgac catgata
//
LOCUS       DAFAZV010000012        93381 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFAZV010000012 DAFAZV010000000
VERSION     DAFAZV010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 93381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.012"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            106..468
                     /locus_tag="KOU88_001282"
     CDS             106..468
                     /locus_tag="KOU88_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211185.1"
                     /translation="MEDLCMDALVYERFVRAAFSIKLNNLINRSEDLGGLAEADIFRA
                     ANNLHELNEIKIGTGYAIAIFNNEILESCNVSDNDSNRMIELFDRSLIATSREEILDI
                     IREYETYRGRYLTFNWKR"
     gene            634..1152
                     /locus_tag="KOU88_001283"
     CDS             634..1152
                     /locus_tag="KOU88_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211186.1"
                     /translation="MDKKIDIAKFIVNRIDYYIEKSDNKASFLLLLNSAIIGFLFSGK
                     EKIMNHLSISNIRCLEMLFYIVILCIFVISIYFSIMVLKPRNSKIENEYKSIFYYKEI
                     ASLNNEQYKEAFENAFKDEENLINDALVQIKELSLICDKKMYNVKKSVEAFILGGIIL
                     FIYILVVVFNAI"
     gene            complement(1216..2802)
                     /locus_tag="KOU88_001284"
     CDS             complement(1216..2802)
                     /locus_tag="KOU88_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211187.1"
                     /translation="MVRIFTMVDDKEYKTQNVNNVHNSAKNENAFNLKKYKEKLQENI
                     NTDIYEKEKEPNHPEVILFFSFDIANSSLYKNINYSGWAKVLSHIIRKLQYRVYENLK
                     AQLWRVLGDEVIFIIVLKNYDEIYKYIDIIFDILTSTAKDIKSGNIFSTLEGFSESEK
                     YLMKLQNIISLKGAAWIAIVSRNPNFNALENNEQYENISAMYDLSNNYKIFEFLGNDI
                     DAGFRISKQTCPERLVLSFELAYILSRKTDILSKLHIITYKKLKGIWKDKLYPIIWYH
                     NKGKNNDIEFDDSFSFDEIEENELVREYFFNKKGESKLLIDSFMFNSVDKALDKILID
                     RNLSDKIEKIGDVISKTNPSYDKNTIDKDYIKVDLMELHCVAVCYNKSTSKILIAKRS
                     DNRNNNASKWEFGCAKASLETSIINTIKDEYEKDFNINIEPITDCTRKDDCQPIPLAI
                     YQVKKSDGLHKGIITLAEIINDYDISKFEPTSKHNELAWIGEDELEDFNENTVPDFKE
                     TLKLAFKKLNENQLQESTNM"
     gene            complement(2778..3299)
                     /locus_tag="KOU88_001285"
     CDS             complement(2778..3299)
                     /locus_tag="KOU88_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBK3211188.1"
                     /translation="MDFKIRELINDITQDIIQTYKIQIPIVNINQVVDALGGKVIEDS
                     SLSGYSDGFIRKVDDSFEIVVSPYQPDTRKNFTIAHELGHLFLHMGYGIDDELWNSQD
                     GNQYFRSGNTNKEYQSNEFAAALLMPKHEYKRIMDENTVGNKVDTSKIAEYFNVSSYA
                     ASNRGKWLGYLQW"
     gene            complement(4001..4189)
                     /locus_tag="KOU88_001286"
     CDS             complement(4001..4189)
                     /locus_tag="KOU88_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211189.1"
                     /translation="MTKTILCDYCNKGINKDDNKYITFHKKSHMKTNICINCALNLID
                     KDKLNENIINNQHGYSKK"
     gene            4443..4619
                     /locus_tag="KOU88_001287"
     CDS             4443..4619
                     /locus_tag="KOU88_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211190.1"
                     /translation="MKTLMFILVIAYYITIVIKSITTIVKSITRLLDSISRLKESLHK
                     LRNRPDGNQDDFNE"
     gene            complement(4838..5014)
                     /locus_tag="KOU88_001288"
     CDS             complement(4838..5014)
                     /locus_tag="KOU88_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211191.1"
                     /translation="MFKNKMDKCTHMLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     regulatory      complement(5069..5166)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            5375..5764
                     /locus_tag="KOU88_001289"
     CDS             5375..5764
                     /locus_tag="KOU88_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3211192.1"
                     /translation="MKQQEVVNKLRRGELMLMEYLWRKNSILSKKEIIEAMKKRYKWR
                     KSTTEILLKRLVKMKTLKKKRIGFQFSYEVLVTKKEYLNAIKEDRKVTKYDSFFIRMF
                     TTMHKKEKMTEEQIKKYIENMEKIGKG"
     gene            5858..6241
                     /locus_tag="KOU88_001290"
     CDS             5858..6241
                     /locus_tag="KOU88_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3211193.1"
                     /translation="MGFKKLPDSELKVMKFIWGLDGNKVASGEVVEAMKQIYDWNKNT
                     TLTILSKLAKKNYLYSQKTSKCTYYTIAVREKDYLKVETKKFFSFFHNNSLKSFFTAL
                     NDEENLSDDKLDMLEEWVKNWEEDE"
     gene            6920..8350
                     /locus_tag="KOU88_001291"
     CDS             6920..8350
                     /locus_tag="KOU88_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK3211194.1"
                     /translation="MILNQIFIEAGGIMRNKIIIGITFSLVLLMSGCASKQTAEINVL
                     ATTDLHGVIPYELTSYVKEERKKDKNLTLVDAGDFFDSGEVFGSSMDSYFSARYKDGD
                     NNTESYIETPISKDMKEVGYDVAVLGNHEFISNNKFYLDNMISDFEKQKINILSANTY
                     KKNGDSYTKPYIIKNINTPEGNVKLGILGLTIKEVGERKQWKDGKLVDSKSLELKDQE
                     GYNGELYMNDLVEDAKKWVGIMEKEKPDIIVAVAHTGEKPKKPKNPGNRIQDLAQQVD
                     GIDAIVAGHNHVQIEQHDYKNKSGENVIVTEPGKHGECISKINFKLEKNNDKWNIVDK
                     SSKLIKFEKNQESDKFGEFISSINKVSKDKKEIRLSEVKTPEWDKIYVFKSGTSADDI
                     YKTIGYKWRNISSPKGDDMVQIVVMNNNKPVSYVYGEAEVMPINIKCDESEYKDNVVT
                     IYPNKNDKFKIEKGKQEYSINLKHIQ"
     gene            complement(8498..8848)
                     /locus_tag="KOU88_001292"
                     /pseudo
     CDS             complement(8498..8848)
                     /locus_tag="KOU88_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904812.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            8843..9364
                     /locus_tag="KOU88_001293"
     CDS             8843..9364
                     /locus_tag="KOU88_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBK3211195.1"
                     /translation="MFSIGGGYAIILLIQEKVVNQTGWISEKMFTDIITISQMTPGPL
                     AVNTSTFVGLQIGGFWGAVAATLGCVLCGVVISLFLYNFFQKHQNSTYIFEILNGLKS
                     ASLGLIISAAATIIILALFGTNKVYFNSIFEMLNWTALIIFFVTLLIVRKWKINPIVI
                     IIISGILGIFFYL"
     gene            complement(9493..10287)
                     /locus_tag="KOU88_001294"
     CDS             complement(9493..10287)
                     /locus_tag="KOU88_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3211196.1"
                     /translation="MIFCNSFITRKSSMNIVVTHTPIVTTLEMQKAYEPLAKHNVNIF
                     AFDFSGTGKSDGYEKDFSRNSIVKDLDSVITYIEKNYSSNIHLYGNTGIGGMFAQYYA
                     CSDNKLKSFAQFACVDYKNTTGVGYTYLTVKLLNFFFKFLPNFHITVKPPKYKGYNEV
                     YDNEFYKIFEKKNPHIWKNSTKIINTMLECFIAKDSKIKDGVNIPTLVFKTLHDRYFK
                     TQYFDSYYNSLKCKKKLVEINNVHNSYYIDSEKFCQEAYDWFVENQ"
     gene            complement(10511..13939)
                     /gene="uvrA"
                     /locus_tag="KOU88_001295"
     CDS             complement(10511..13939)
                     /gene="uvrA"
                     /locus_tag="KOU88_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBK3211197.1"
                     /translation="MKINNYKNQSIITNPKKFENKYQDLPKTPIELLKVVQSLVIHGD
                     QGKLYGISFNKQQSDEELLRTIPQMLKRIFEINSNPLTIPRNPKQRLVGMCRDYSLLL
                     VSLLRYRGFEARMRAGFANYFESELTYEDHWLVEYYDTLTKRWIRIDAQIDDIQKNYF
                     QINFDTHDVGKTDGFLTGSEAWIRCWQGHAHPDDFGYNKNWKGWHSVKGNLLHDFNNM
                     IGLELLPWDLWTELSSKKYNQLTRAEKNLLDEMAEILSSGNIKIEDLNLLIEKLPEDY
                     LKSIFSQLKILGISEIKELGNPLELEKKFKFTKSINKSIKNSLCHNKSSIYLKGGRQN
                     NLKDVEVTIPKNQITVITGVSGSGKSSLAFDTIYEEGKRRYFENLGNGAKLSEQLQKP
                     EFDLLQGLTPTIAIEQKKGSQNPRSTVGTLTSIWDYLRMLFVSIGKSYCPYCKIPLEK
                     KNNTKNYCPHCQTIFSKINTSTFNANSHTGACHDCNGLGFTYQVNPQLIVKDPTVSIL
                     DGATYYFGKLRRKKPNGNWMLGELYAIAKDKNIDLDIPWNELPREFIDAILYGTDDKI
                     YEFSFESKGRESKIRRPASGAINHIQRLFRESSSENNTLHQYMNKIPCNTCGGELLCI
                     EARFTTIKGYRFPELTKMTIEQLWNWLCELPNQLQKNELSLVNDILTELKIRVSYLLK
                     VGLSYISTDRTAPTLSGGELQRVRLSSQLGSELVGLTYILDEPSIGLHPRDHNLIIKM
                     IEELRDKGNTVIVVEHDKDTILSADYIIDVGPNAGTKGGFIIAEGTTQEIIKNPNSIT
                     GKYLSTYNKTGSQNKTIPSKWLSLKGCHANNLKNIDVEIPLNCMCSITGVSGSGKSSL
                     VFHSLLPALEEKLKQKSSPDKNYTEFTGFDAIDDFILMDQTPIGKSSRSTPSTYINIF
                     DEIRSLFAETPQAKQKLLDESYFSFNSKKGQCPNCQGLGKTKIILQYMADQWVTCSEC
                     QGKRYQKEILSIQYKGKTIADILDMEVTEAKTFFSDCSNIYRKLSLLDEVGLGYLKLG
                     QNTLGLSGGESQRIKLAKELGTKTKKRMLYILDEPTTGLHFKDIENLLITFRKLVNEQ
                     HSLLIIEHNTEVIRASDWIIDIGPDSGINGGEIVASGTPDEIKINPNSITGHFI"
     gene            14258..16492
                     /locus_tag="KOU88_001296"
     CDS             14258..16492
                     /locus_tag="KOU88_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3211198.1"
                     /translation="MKLSRYKKNSLVLSIILCSLIISILVITVFNTVKLHNISNKQSK
                     NYLNDVSTQIVMNVDSKIKFILSDLRIMADFIKQYEGDSRYEYLSKRKTSYKYYDVGI
                     IDLEGKAEFLSGKKFDLKNTASYKKGIEGKEYSEVIESMGFVLYSVPIFNDNHEVSSI
                     LIGVSNKESMNEILNIDNFNGEGTIEIINSKGKPLFIGKNTELIKDLSHKYKDSADEP
                     WAQKMLNDFKNDKSGNITITSSKGVQCLLTYHPITIGLNDWHFLLIVPEDAVLGELNK
                     LNSFTITMTFIITCIIGIITLILYIIRRKYVNQIENIAYLDSITNGINSTKFSMLVKP
                     LISESPDSTYMMIAMNIKDFKLINDCFGSEKGNMTLKHLYNILYKNIDENEEFVCRHD
                     ADLFYLLIKNRPVLEALELLYKIEADTNYFNKNRENPYFLRLSVGIYTIENHNEDLIT
                     IQDHANTARKSFNKTHQSDFSFYSDIERKRLISEKEISNLMEKALENKEFFMCLQPKI
                     DIKSGKISGAESLVRWKNSEKGIIYPSDFIPLFEKSGFICKLDLYILEETCKLISKWI
                     KEGKEVLRISVNVSRQHLNDKLFLEKYKHICNKYNVPTCLIDLELTESIFLENPEAID
                     IIEDIHSNGFKCSIDDFGFGYSSLGILKDFKVDIIKLDRSFFVSKNNIDRGKVVIKSI
                     IELSKRLGMKVTAEGIEELEQVEFLKNVGCDYIQGYVFSKPLLISDFENFAYENNKIK
                     NIHY"
     gene            16748..18778
                     /locus_tag="KOU88_001297"
     CDS             16748..18778
                     /locus_tag="KOU88_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3211199.1"
                     /translation="MISGRMLLIMNFLKGKNKTSYKDISKQLSIEERKVRYDINNLNI
                     VLRSLNKSVIQKMNKGVLIIPDDFQVVCINNNEYVFSLTERVSIMKIISMFKIDNLNL
                     EKLSKEFQVSRSSIKNDLNVLSSELERNQITITYDKSFKISGEEDIIYKQRLNILKSY
                     SYLFGKEKSDLSVFEKYLVNVIEKIFKGIYLIDIYNWSMNLLLQMGWTLNDESFTWYV
                     SNIFLFTWYIHSDEKHPLESASLSEPCFENKFDQEFETIIQKKLTKEQIFLLKSFVFF
                     TNKYASLNEDMDLISTEIIVQDLIYNMSEILEISFKEDMILYKGLLNHIAPLIERIKQ
                     NIQIYEELLHVIPDKYQYVLEATKVSIQKNRVLSQIKNENETILLAIHFLGSIHRNER
                     NNYKNILLVCGFGYGVIAMLKDSLVNDYQINIVESIPSYKLQDYKEWESIDFIITTSK
                     IVIDLPKTIIEINPFLQEEDYLKFEEKGIKRKNVLTNYMSIKKRLDFLEEDAQKRVLS
                     IICQELGYSDERILFRQLNLSDLIGIDTIRIIDGDMKWEDAVKFSSNILANCDFVSAQ
                     YAENIIDILKNVGFYAVKDNEFALLHGNDSSLVKVSSISLLICKEAVSFGDKKVKIIF
                     CLASRDKKEQIPAIINLTKMVYKTNFIAMLESAKTKEEAEVLIHKYEKEVTV"
     gene            18775..19227
                     /locus_tag="KOU88_001298"
     CDS             18775..19227
                     /locus_tag="KOU88_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3211200.1"
                     /translation="MNKLVNVKCSFKIHVNSKEEAIISLVDVVSKEGYLIDKNQFLKD
                     VLKREETLSTYIGHGIGLPHSQSVGVKNSCITIGKLDTPIEWTEEGEKVDLIFLISVT
                     KDNENNLHLKILSKLARLLMHESFRNQIRCSDEQTVYNLIKEKIEEED"
     gene            19229..20284
                     /locus_tag="KOU88_001299"
     CDS             19229..20284
                     /locus_tag="KOU88_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBK3211201.1"
                     /translation="MRILKFLQKHLMTATSYMIPFVVAGGILFALSVTLSGQAAVPET
                     GWLAKLNQIGAAGLALFIPILGGYIAFSMADKPGLAPGMIGAYLAKEVNAGFIGGIIA
                     GFIAGFVVLQLKKIKLAPTMRTLGSIFIYPLVGTLITGGIIVFLIGEPIASFMTWMTN
                     WLNGMSGVSKIPLGGILGGMIASDMGGPINKVAATFAQTQVDTLPYLMGGVGVAICIP
                     PIGLGLATLLFPKKFSKEERDSGKASLLMGCVGITEGAIPFATSDPVRVIPCIMAGSI
                     VGNIMAFLLGCLNHAPWGGLIVLPVVDNRLGYIASVLTGAVVVAVLMKLVKKDVKEDE
                     EIEEDLDESIELIFEEL"
     gene            20351..20659
                     /locus_tag="KOU88_001300"
     CDS             20351..20659
                     /locus_tag="KOU88_001300"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBK3211202.1"
                     /translation="MKIVAVTSCPSGVAHTYMSAESLELSAKKFGIEIKVETQGSSGI
                     DNELSLKDIDEATCVILTNDVEIRNMERFKGKKVVRMSVSEIIKKSDALIKKIKDTFQ
                     "
     gene            20763..22028
                     /locus_tag="KOU88_001301"
     CDS             20763..22028
                     /locus_tag="KOU88_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II D-tagatose-bisphosphate aldolase,
                     non-catalytic subunit"
                     /protein_id="HBK3211203.1"
                     /translation="MKKLPIKTVVQRLLNLQEEGKSATLLGIGPMSPNLLQASFELAK
                     DDDFPLMFIASRNQVDADELGGGYVNGWNQETFTKDIKKVADKVGFDGLYYLCRDHGG
                     PWQRDKERNDHLPVDEAMELGKKSYLADIEAGFDLLMIDPTKDPFEIGKVIPLDVVLE
                     RTVELIEYCENERKRLNLPDIGYEVGTEETNGGLTSTETYETFITRLKVELDNRGLPM
                     PTFIVGQTGTLTRKTEQVGTFNFRNAYDLAQMAKKYGVGLKEHNGDYLDDVTLLEHIP
                     SQIIATNVAPQYGTEETRAYLKLAEVECKLEKEGLVEKTSNIRHVLLVNAIECGRWRK
                     WVVGEQKNLTTEEIFKDEVLSNEILDIAGHYTFNNDDVKKEIEVLYDNLSKNNIDGQR
                     FVVDHIKRPLRDYAECYNLKGVTTRILNK"
     gene            22116..22832
                     /locus_tag="KOU88_001302"
     CDS             22116..22832
                     /locus_tag="KOU88_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK3211204.1"
                     /translation="MINLIFDVDDTLYNQLTPFYTAYNKVFSSIKDISIEDLYMSSRK
                     YSDEVFHMTENGEMPIKEMHIYRIMKAFEELGNSITEKDAQSFQDEYIYQQSQITLIP
                     EVERILNFSKERNINLGIITNGPSNHQRMKLKQLNIENWVDKSNIFISSEVGFSKPDT
                     NIFRVAENVMNLDRENTYYVGDSYRNDVLGAKKAGWKSIWLNHRGHEVEELFYKPDFV
                     ILEHKDLISLFIKICSYKNM"
     gene            complement(23027..23320)
                     /locus_tag="KOU88_001303"
     CDS             complement(23027..23320)
                     /locus_tag="KOU88_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HBK3211205.1"
                     /translation="MRNMIENLIKNNTYIDDKVIMLSMLSSAKASANMYLNSALTSST
                     PELRAIYSASLTQMVEGHTALTELSINKGWVKPYDKPIQQLTCSYKESQNVID"
     gene            complement(23326..23541)
                     /locus_tag="KOU88_001304"
     CDS             complement(23326..23541)
                     /locus_tag="KOU88_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211206.1"
                     /translation="MRILSETEKISLAAIIKMESDGLLMQRAINMLISDEDLKRQSES
                     SILATEGRIKAIQQFIVENEILISEEV"
     gene            complement(23953..24465)
                     /locus_tag="KOU88_001305"
     CDS             complement(23953..24465)
                     /locus_tag="KOU88_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK3211207.1"
                     /translation="MLEVIKNRRSIRTYIDKNIEEDKITEILKSAMQAPSSKNAQPWE
                     FIIVDDKELLKQLSKSQHRAKHIEFAPLCIVVLGNRDKFLKPGKWIQDLGACTQNLLL
                     EVTNQGLAACWAGVFPKNKVVNKVRQTLDLPLKLVPYALISIGYSEEKNEFIDRFDEN
                     KIHRNVYKNR"
     gene            24915..25391
                     /gene="purE"
                     /locus_tag="KOU88_001306"
     CDS             24915..25391
                     /gene="purE"
                     /locus_tag="KOU88_001306"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBK3211208.1"
                     /translation="MKVAVVMGSKSDYPKLEEGIKLLEKYGIEVVARALSAHRTPEQL
                     SIFLKEIEDDTDVIIAAAGKAAHLPGVIASQTLIPVIGLPIKSSTMDGLDSLLSIVQM
                     PKGIPVATVTIDLGLNAALLALQIMTLKYPKLKEDLKSYREEMAQKVLEDDKNLRG"
     gene            25397..26095
                     /locus_tag="KOU88_001307"
     CDS             25397..26095
                     /locus_tag="KOU88_001307"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBK3211209.1"
                     /translation="MLLYEGKAKQVYSTDNENEYVVYYKDDATAFNGEKKAEISSKGI
                     LNNKISTIIFEMLKENNINTHFIKSLSDREMLVKKVEILPLEVIVRNIAAGSICKRVG
                     LEEGVVFDEPIFEISYKNDAYGDPMLNDDYAVAMKLATREELKFLREETLKINELLKA
                     FFLKLNLKLVDFKIEFGKDSEGNIILADEVSPDTCRLWDVNTNEKLDKDRFRKDLGDL
                     VEGYTEVLSRMNNK"
     gene            26107..27474
                     /gene="purF"
                     /locus_tag="KOU88_001308"
     CDS             26107..27474
                     /gene="purF"
                     /locus_tag="KOU88_001308"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBK3211210.1"
                     /translation="MCGVLGIYSNKDVTKELYYSLYSMQHRGQESCGLALLDDGEIKY
                     KKDMGLVGDVFKENELSKLKGNIGIGHVRYSTAGGSHVSNCQPLVGSCRKRQLAIAHN
                     GNLVNANYLKDMLEEDGYMFQTNSDTEVILYILARYYKGDIVESLKVTMDYIKGAYAL
                     VIMSQEELVAVRDPHGFRPLVLGKKGDEYIFASENCAIDILGGEVIRDVEPGEIIVVK
                     DGELKSYFYSENYKPVKKSCIFEHIYFARNDATIDNVNAYEFRIKCGERLAQNETVKA
                     DMVVPVPDSGWPGAIGYANASGLKISEGLVKNRYVGRTFIKPTQEEREIAVKIKLNPL
                     STIIKGKSIILVDDSIVRGTTSKQLVKSLREAGAKEIHLRITSPPVAYSCYYGIDTPN
                     RSKLIASSNNVEEMREYIGCDSLKFLDIEGMLDATEHKSTFCKACFDGEYPVKKIDKE
                     ELLSC"
     gene            27468..28544
                     /locus_tag="KOU88_001309"
     CDS             27468..28544
                     /locus_tag="KOU88_001309"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBK3211211.1"
                     /translation="MLTYKESGVDIDEGNRAVDLIKGKIKGTYDGNVVGDLGNFSGLY
                     SLKDFVGMKEPVLLASTDGVGTKLKIAQMMDKHDTVGIDLVAMCVNDLICQGAKPLFF
                     LDYIALGKLVPEHIEKIVGGIADGCKMSGCALIGGETAEMPGMYGEDDYDLAGFSVGI
                     ADKEKIVSGNNVKSGDVLVGISSSGVHSNGFSFIRKIFLETYNYKMEQYVEELGMTVG
                     EALLTPTKIYVKLALDVLAKHDIKAIAHITGGGLIENITRVIPKGLGLDINKKSWEKP
                     PIFKMIEGFNAVDERELHKSFNMGIGLVLIVDKENADDVVNFINNRENDNADYVDKKY
                     SELLEDKAYIIGEVVDSHEGVELC"
     gene            28538..29131
                     /locus_tag="KOU88_001310"
     CDS             28538..29131
                     /locus_tag="KOU88_001310"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBK3211212.1"
                     /translation="MLNIGVLISGGGTNLQAVIDGTESGEIKGQVKVVISSKQGAYGL
                     ERAKNHNIKAICETDEDKIIEILKENKIDLVVLAGYLKIISPKLVNEFRNKMINIHPS
                     LIPSFCGAGFYGEKVHQGVIDYGAKVTGATVHFVDEGADTGPIIMQDVVKVNQDDDAK
                     TLAKRVLEVEHRILKESISLFCENKIKLQGRRVFINE"
     gene            29124..30656
                     /gene="purH"
                     /locus_tag="KOU88_001311"
     CDS             29124..30656
                     /gene="purH"
                     /locus_tag="KOU88_001311"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBK3211213.1"
                     /translation="MSKRALISVTDKTGVVEFAKELNKLDYEIISTGNTFKTLKENGV
                     NVMQVEDVTNFPEILDGRVKTLNPYIHGGILYKRDKESHVETVNEHKIHSIDLVAVNL
                     YDFEGTLKAGKSHDEIIENIDIGGPSMIRSAAKNYKDVIVVVDIKDYDSIIEKLKTDT
                     MTLEDRKKLSYKAFSTTGRYDALISSYFAGEVGDTYPDILNLTFQKEQTLRYGENPHQ
                     NGFLYSQSNAKNPILNYEQLGGKELSFNNLNDLHGCLEVMREFKDSEEVVSVAIKHAN
                     SCGVGLGKDAFEAYTKCYEADKVSIFGGIVGITSTIDKATAEKLNEIFLEIVVAYDFE
                     PEALEILKQKKNLRILKLAKIENSLQPYEMKYLDGKLLIQDRNNILAEKSENVTKEKP
                     TDAQLKDMEFGMRVVKNMKSNAIAIVKNGQTLALGCGQTSRIWALKNALENNKDKDFT
                     GAVLASDAFFPFDDCVTLAHEYGISAVVQPGGSIKDKDSIEACDKYDMVMVFTGIRHF
                     KH"
     gene            30667..31917
                     /gene="purD"
                     /locus_tag="KOU88_001312"
     CDS             30667..31917
                     /gene="purD"
                     /locus_tag="KOU88_001312"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBK3211214.1"
                     /translation="MKILVVGGGGREHAICWKLSKEKNVEKIYCAPGNAGIANVAECV
                     NIGDTNIEELLKFAKENEIGLTIVGPEVPLVMGIVDEFEKEGLRVFGPNKKCAQLEGS
                     KAFSKEFMIKHNIPTAKYKEYTNLEEAISEIDSFGYPVVIKADGLAAGKGVVIPENRE
                     DAIATLKEMMSDKKFGAAGDKIVIEEFLKGIETSILAFVDNDTIVPMASAKDHKKVNN
                     YEQGPNTGGMGTFSPSEIYTEELANKVKETVLEKTLEGFKKDGLNFKGILFVGLMITE
                     DGEKVLEYNVRFGDPETQSVLFRLETDLHEIMEAILDNKLKDIEINYSDDEAVCVMLT
                     SGGYPDSYEKGKIITGLENLDDDIVVFHSGTKMFDGNLVTNGGRVIGITAKSTTVKDA
                     AEKVYENIKKINFEGMHYRTDIGR"
     gene            31942..35748
                     /locus_tag="KOU88_001313"
     CDS             31942..35748
                     /locus_tag="KOU88_001313"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBK3211215.1"
                     /translation="MLNTENKDSMVRRVLVEKREGFDLEAKALKKDLVESLHIDNIEN
                     LRILNRYDVEGISEEVYENAAKTIFSEPNLDVVYYEEIPKLNDERVFAIEFLPGQYDQ
                     RGDWAAQCVQIVNQGIRPAINTAKVYILSGKITDEEFSKIKDYCINPVDSREASLEKP
                     ETLKMETEIPTTVEVLDGFIDLDENGLKTFVSEKGLAMTLGDLQHVQKYFKDTEKRNP
                     TITEIKVLDTYWSDHCRHTTFMTEIENVKIEDGKFNDIVKEAYQMYLNSRDNVYVNRH
                     KDICLMDIATVAVKELKKNGKLNDLDESEEINACSINVDVEVDGKMEKYLVMFKNETH
                     NHPTEIEPFGGAATCLGGAIRDPLSGRSYVYQAMRVTGSADPRTTLEDTLPGKLMQRK
                     ITTEAAHGYSSYGNQIGLTTGQVAEVYDENFVAKRMEIGAVIAAAPKENVVRERPEAG
                     DVIVLLGGKTGRDGCGGATGSSKEHSEESILTCSAEVQKGDAPNERKIQRFFRNKEVA
                     QMIKRCNDFGAGGVCVAIGEIADSLDINLDLVPKKYDGLDGTELAISESQERMAVAIK
                     KENKDKFIQLAVEENLEATHVATVTDTGYLRMFWNGKAIVDINREFLDTNGVKQTTDV
                     HVTKVDEENTFFSSNEIVKDVKCASMKDKFTKVLSDLNVCSQKGLVEMFDNTIGGNTV
                     LMPFGGKYQATPTQGMVAKIPVLGGETNTSTIMTYGYNPKVGKWSPFHGALYAVVESV
                     CKLVAIGGNYSTTRLTFQEYFEKLGNNPEKWGKPFSALLGAFYAQSKFEIPAIGGKDS
                     MSGTFKDIEVPPTLVSFAVDTVDAKKVVSPEFKKADSKVVMLCVNKAENDVVDFEELK
                     RNLDKVRELIHGNKVLSTYALGFAGVGEAISKMAFGNKIGFKFSEEAEKAFTDDKLFE
                     ASYGNIVLELANDDLSMLEGYNYVVLGSTVKEASIFIKGEELALDELYKAHCSTLEPI
                     FPTKTEEVKSKIETISYISQGEAKKSSLSIATPRVFIPAFPGTNCEYDSARAFERAGA
                     NASIRVFKNLTYKDIEDSIDTIVNEIKSSQIIMLPGGFSAGDEPDGSGKFIATVFRNP
                     RVQEAINEFLTQKDGLMLGICNGFQVLIKLGLVPYGEIRVPSESAPTLTYNNIGRHQA
                     KIARTRISSNKSPWLAQTNVGDIHNIAISHGEGKFVASEDVMRELIANGQVATQYVDF
                     NNEATYDIEFNPNGSFYAVEGITSADGRVFGKMGHSERIGEEVYKNIIGEKDQKIFES
                     GVKYFR"
     gene            35954..36826
                     /gene="rfbD"
                     /locus_tag="KOU88_001314"
     CDS             35954..36826
                     /gene="rfbD"
                     /locus_tag="KOU88_001314"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBK3211216.1"
                     /translation="MKILITGSNGQLGKELVNQLEAINQSINQPKYVILATTRSDLDI
                     SNQTNVDNFILHNKPDVVVNCAAYTKVDACEDNIEIAYKINALGVRNLAIASEKVNAK
                     LIHISTDYVFNGFSKYPYREDNKTEPNSVYGKSKLMGEKFVEQFSHKYFILRTAWLYG
                     NGNNFVKTMIKLSLENKEVNVVNDQFGTPTSTVDLAKIIIRIMETEHYGVYHATCEGE
                     CSWYDFAKKIFKLKNIDIKVNPIKSNEFKCKAPRPLYSVLDNFMLKLIGLNSFRKWEE
                     SIEEYLERYDINEK"
     gene            36935..37804
                     /gene="rfbA"
                     /locus_tag="KOU88_001315"
     CDS             36935..37804
                     /gene="rfbA"
                     /locus_tag="KOU88_001315"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBK3211217.1"
                     /translation="MKGIILAGGSGTRLYPITKCISKQTLPIYDKPMIYYPMSVLMLA
                     GIQDILIISTPRDIKAFEELFGDGSSLGINITYAIQEKANGIAEAFIIGEEFIGNDRV
                     SLVLGDNIFYGYGFSERLENAVKRKGATIFGYHVSNPNSFGVVEFDKDFNVLSIEEKP
                     TVPKSNYAIPGLYFYDNDVVEIAKLVEPSDRGELEITSINSEYLKRGKLKVELLGRGM
                     AWLDTGTHKGLLDASNYVEVVQTRQGLYIACLEEIAYTKGYISREQLMKLAKPLIKTE
                     YGQYLLKLASEDM"
     gene            37853..38410
                     /gene="rfbC"
                     /locus_tag="KOU88_001316"
     CDS             37853..38410
                     /gene="rfbC"
                     /locus_tag="KOU88_001316"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBK3211218.1"
                     /translation="MGKINVIKTKIEGLYIVEPNVFYDERGYFMESYNKKDFIEQGLD
                     MCFIQDNESSSRKGVLRGMHFQVKYPQGKLVRVTEGEVFDVAVDLRKDSQTFGKWEGV
                     ILSDKNKKQFYIPEGFAHGFLVLSEKAVFSYKCTNYYYPEFENGFIWNDKQISIEWPL
                     KGIEEIFLSEKDKKQKSFKDICTRR"
     gene            38448..39431
                     /gene="rfbB"
                     /locus_tag="KOU88_001317"
     CDS             38448..39431
                     /gene="rfbB"
                     /locus_tag="KOU88_001317"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBK3211219.1"
                     /translation="MKKILITGGAGFIGSNFIHYMLNKYVDYFIVNLDLLTYAGNLET
                     LIEIQDNSNYKFVKGDISNREQVYKLFEEERFDIVVNFAAESHVDRSVENPDLFIKTN
                     IIGTQVLLDASIKYGVKRYHQISTDEVYGDLPIDRKDLFFTEQSSINPSSPYSASKAS
                     ADLLVNSYYRTYGLLTTISRCSNNYGPYHFPEKLIPLMILNALENKQLPVYGNGENVR
                     DWLHVYDHCTAIDLIIHKGNIGEIYNIGGHNERSNLEVVKVILNLLGKSEELISYVND
                     RPGHDLRYAIDATKIENELGWKAKYDFDLGIKETVKWYIENESWWKAVLSV"
     gene            39461..40129
                     /locus_tag="KOU88_001318"
     CDS             39461..40129
                     /locus_tag="KOU88_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBK3211220.1"
                     /translation="MNEISSLINILALTQLSGSNTTNQCNCTYNNSSGFDMIMMTLLK
                     ALSQNNQHTSNSYNLLSNSENLFNELDNVVNNTTSRFIDVDTKDKNVKLRIENAVDQA
                     SKKYNVDSNLIKAIIKVESDFNPNTVSSAGAKGLMQLMPENCRDLGVTDPFNIEQNID
                     AGTRHIKEYIDMFGGSIEMGLMAYNGGPGRMKSRGVESISDLYKMPKETQNYIPKVMK
                     YYRG"
     gene            40138..40566
                     /locus_tag="KOU88_001319"
     CDS             40138..40566
                     /locus_tag="KOU88_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaaR family protein"
                     /protein_id="HBK3211221.1"
                     /translation="MGINIDKLNISPSINMEVKKLKESNKFSDKLNSLKQSSSLEDIK
                     RNLESVKKAGERLVLTQNYGDISIYKNAVKEYLKSVVDNMYSLDKNSSFWEHQYYKNV
                     KIVDSKLEDMTSKLISEEKENIDIVSTVDMIQGLLIDMYR"
     gene            40590..40904
                     /locus_tag="KOU88_001320"
     CDS             40590..40904
                     /locus_tag="KOU88_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBK3211222.1"
                     /translation="MNSKKEDIYELNFGQLIEEKSGVIEENQNVFNAKVNVAVSIGNT
                     TETIKNILDLKEGSIIKLSKNVDEKLDIYANDRLFAYGESIITNERLSVRLSKIEDPD
                     VN"
     gene            41056..41331
                     /gene="flgM"
                     /locus_tag="KOU88_001321"
     CDS             41056..41331
                     /gene="flgM"
                     /locus_tag="KOU88_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis anti-sigma factor FlgM"
                     /protein_id="HBK3211223.1"
                     /translation="MDIKNVSSNIVVNNYLKNTSGIKKVEEVKKINKTDKIELSKFAK
                     EMASVSNMSDENIRNKKVDEIKNALENGTYKIKPKEIAKKMIEDMRG"
     gene            41336..41752
                     /locus_tag="KOU88_001322"
     CDS             41336..41752
                     /locus_tag="KOU88_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlgN"
                     /protein_id="HBK3211224.1"
                     /translation="MITDLKVIIYEEKNIISKMMELLKEQFDYIVEKDLENLNMLNPK
                     LEDISRELASIEIKRRQLFGDDISMSEVVENSNDGYLKEIYTDLKHILALAKNQQESN
                     DSLIKKELIFTKKMINFIKPADKKTTTYNSYGNIRK"
     gene            41770..43080
                     /gene="flgK"
                     /locus_tag="KOU88_001323"
     CDS             41770..43080
                     /gene="flgK"
                     /locus_tag="KOU88_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBK3211225.1"
                     /translation="MAGLFSILNTANSGMNAHQKAIQTISHNISNLDTDGYSRQRTEF
                     ATNSPMYMPSLSNSIARGQLGTGVHVTDVTRARNSFYDYQFRAEAHKYGKTVSKYDYY
                     NTIETILNEPSDYGISAGIDDFFKGWESLSKDINSDSKKSLVVENASNLATLISESYK
                     KLDKLKEDIDSNIDTEIKQINDMLKSLEDLNKSIDIISGSGSTPNDLLDERDRILDNL
                     SFKLDFENSDVKNMLADGKLELNELKNPDGTWKTGISGTLQGLFEMHGKIDTYKSDLK
                     DVSDGLAKQINDVYNTSAGITVTDFFITSNVDGEDIIKINPAIKSNPNELKLTADEAS
                     KIAKLKDEKIDIGVAGGKVSTISDHYKAFAESIGLDSQKVNQDEANQRKIINNIDNSR
                     MSVSGVSLDEEMTELIKIQRSYQASAKVMSTAVQLLDVVINGII"
     gene            43099..44031
                     /gene="flgL"
                     /locus_tag="KOU88_001324"
     CDS             43099..44031
                     /gene="flgL"
                     /locus_tag="KOU88_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBK3211226.1"
                     /translation="MRVSTGMMSSSYLNSLQDNLQRLDKVNRQVNTTKEINKLSDNPY
                     KAIKILNSKSEIKTMETYVENCKDTGNWLETTDTALDQLGKLLSDIKKTLVASGDGAY
                     SDDELKTLSNETNEKMKEIANALNATHEGKYIFSGSNTGVPPVECIDNADGSVSLKFN
                     SSLNLNKLNDSLSMDIAQGISVDYNVKLSSLGFDPTKTDPFEELNNISKKLANPDADA
                     IKELTTTCLGDMEQLIENTVNVRSIYGTKANTVEAMKEKNDDSLIQLKDILSQNEEID
                     YGEKLVQLKAAELTYQASLQTGGKLFNVSILDYI"
     gene            44047..44439
                     /locus_tag="KOU88_001325"
     CDS             44047..44439
                     /locus_tag="KOU88_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliW"
                     /protein_id="HBK3211227.1"
                     /translation="MMKVTLKKGILGFENLKEYELLDIEDNDYLKEFNSTEEEGIGFV
                     VVSPFEIINEYEIVLNQETIEKLEVKSPKDVVLFNIITLGQTFEESTVNMKAPIVINI
                     KTNFGMQIILQDDKYSIRHPLLRGDNGC"
     gene            44433..44645
                     /gene="csrA"
                     /locus_tag="KOU88_001326"
     CDS             44433..44645
                     /gene="csrA"
                     /locus_tag="KOU88_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBK3211228.1"
                     /translation="MLVISRKKDEAVLIGESIEVKIVGVDGNNVKLAISAPNNISILR
                     KEIYEKVKSENIKATNKNIKILKSLK"
     gene            44667..45062
                     /gene="fliS"
                     /locus_tag="KOU88_001327"
     CDS             44667..45062
                     /gene="fliS"
                     /locus_tag="KOU88_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBK3211229.1"
                     /translation="MYGENPYNSYKQNAVFMASKEQLLLMLVDGAVKYTKIAKTAILD
                     KNTQKAHRELIRVQDIFTELMVTLDQNAGQWAKDMYRVYDFVRYELSRANIRKDIQII
                     DNVLPVIEQIKDTWHEADKKSKEERSRYK"
     gene            45062..45418
                     /gene="fliS"
                     /locus_tag="KOU88_001328"
     CDS             45062..45418
                     /gene="fliS"
                     /locus_tag="KOU88_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBK3211230.1"
                     /translation="MELNLAELDKLSKEELLLMLVDGTVKYTNISKEALLNNDYLKAH
                     NELVRVQNIFTELMTTLDQDAGQWAKDMYKVYEFIKSELAIADENKDIKIIDDILPIV
                     KQIRDTWHEVYNQLKI"
     gene            45439..46962
                     /gene="fliD"
                     /locus_tag="KOU88_001329"
     CDS             45439..46962
                     /gene="fliD"
                     /locus_tag="KOU88_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBK3211231.1"
                     /translation="MSSISPIRVTGLSGNFDMEGIIEASMIRDKEKVDKAKQEQQIVK
                     WKQEIYRNVIQESKDLYDKYLSVNSPNSIVSEKAYSSTRITSSDESIIVAKGSAGAEK
                     INYQFAVSQMAEPAKFTIKLNSSEPIVQQFPPNASGASSLTIGDVNIPISEQDTTSTI
                     VSKINSLCADNDIKASYSEMTGELIISRKQTGSSSDINLRVIGNDNLAQQIANDNGIT
                     FINDAGGNKVANVYGKNLEADVTDEHGRVTHISKEQNSFNIDNIDYNVNSKGTAKLTS
                     VTDTEEAVKNMQAFVDDYNKLMDKVYGLVTTKKPKDYPPLTDAQKEDMTTEEIEKWEK
                     KAKEGILRNDDELRGFVEDIQSAFFGDGKNIIALRKLGINESENYNKKGQISFNADTF
                     SKALIDDSDKVYKTLAGYSSNYDDKGMFEKLKDIVYEYSGSSTSKLPKKAGIEKTASA
                     SENVYSKQIAEQERNISRLVEKMNDKEKRLYAKYSALESLLNQYSSQMNYFSQAQGN"
     gene            46965..47300
                     /gene="fliT"
                     /locus_tag="KOU88_001330"
     CDS             46965..47300
                     /gene="fliT"
                     /locus_tag="KOU88_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliT"
                     /protein_id="HBK3211232.1"
                     /translation="MDKLKEKLNLYKDISLQIINLIEKEEYIKISIKLGERQEIINSV
                     SEIDRNDFIQLYNRMELIEIDSRIRDILQGQLLEVKKELHEYKLTKQVNTMYYNLNRE
                     KVNIFNKKV"
     gene            47402..48274
                     /locus_tag="KOU88_001331"
     CDS             47402..48274
                     /locus_tag="KOU88_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin"
                     /protein_id="HBK3211233.1"
                     /translation="MRVNTNVSALIANNQMGRNVNAQSKSMEKLSSGVRIKRAADDAA
                     GLAISEKMRAQIKGLDQAGRNVQDGISVVQTAEGALEETGNILQRMRTLSVQSSNETN
                     TAEERQKIADELLQLKDEVERISSSIEFNGKKLLDGSSTEIRLQVGANFGTNVAGTSN
                     NNNEIKVALVNTSSIMSKAGITSSTIASLNADGTSGTNAAKQMVSSLDVALKELNTSR
                     AKLGAQQNRLESTQNNLNNTIENVTAAESRIRDTDVASEMVNLSKMNILVQASQSMLA
                     QANQQPQGVLQLLG"
     gene            48367..50508
                     /locus_tag="KOU88_001332"
     CDS             48367..50508
                     /locus_tag="KOU88_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK3211234.1"
                     /translation="MLLSIVMIVKNEEKILEKTLKSLTTLRNSIESELIIVDTGSTDD
                     TIKISKKYTEKVYFHNWNNDFSSMRNISISYAKGEWLLILDADEILIDSSTIVKFFKD
                     GLDKKFNSASIQLKNLYSYDKKLYGYCSVLRLFKNVDFRYHGKVHEQPIYKNPIFNNV
                     ADFEHYGYLFEDEEIRLNKVKRNEKLLFQELKENDNSPYTNYQLGKNFIILGKYQEAL
                     YYLEKSYELYSKLELAPGYLITSLVKTYLYLGKHKKCERLCLKYIKKDMNNIDIYYYI
                     AQAQVDLGKYENSIDSYKRYIYLLDNYEISTQANSLFSDTDTVGLRDEAIITLIKIYY
                     KLEKYEFVISEYNNIEDVEKKKNVYFSLFMSLYKLNRFEDIKNYYKEVSNSKIEKNSF
                     YRNIEEVINNIKEDEKEYVYKILCDIEGNYGILNQIRINKCVSIDKCKEILNEEKEII
                     YAYIIKIAFEEKIDLLDIFYEMEYVWIEKYLKYLLALERSFNLVLYKYIISRPNTSDM
                     EKIRVYKAISKVVLESISLSDEKYKEIFYLYIMYSYKYIRYIYSNLSDFELIKFVCND
                     LDKFTIEFKHLLDIKNKVNNANEKLEYIHSMRKLLNEYPFYNKIIKILIGELEENIKE
                     SEEFKDLKDSFIISIENMIETGKINDAKLLVDDYSKTFVDDIKILNIKGILYMFENKL
                     DKADFMLKKALSLDVENEDTIYNIEYLKSLR"
     gene            50532..52409
                     /locus_tag="KOU88_001333"
     CDS             50532..52409
                     /locus_tag="KOU88_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK3211235.1"
                     /translation="MNIPIVVNEKSKDIIKDWQYTCTNEDIKFTSIIILTYNQIEYTK
                     LCIESIRKFTPKNKYEIIIIDNNSSDGTVEWLKGQSDIKSVYNNKNLGFPKGCNQGIE
                     LATGENILLLNNDVIVTPNWLYNLNKALWSQDNIGAVGPITNACSYYQQIDVDYKSIE
                     DMFIFAHKINKSNINLWKYRLKLVGFCMLIKKTVLDNVGVLDELFTPGNFEDDDLSFR
                     MIESGYKLLLCQDTFIHHFGSVSFKENRNKYTDIMYINRRKFETKWGFNPEYSGMIRT
                     DLISKIDDSLEANINVLEIGCGIGATLLEIKNIYKNASIYGIEISESAGKLAKYSADV
                     LIANIEKVKLDYKKDFFDYIILGDVLEHLIDPWKIVNELKQYLKKDGYLVSSIPNIMH
                     VSVLRNLVLGNFTYEDSGILDKTHLRFFTLNEITKMFNDSNYIINSITATSMPLSEID
                     NSFIDTICKESCKEMRQQYESYQYIVKASKILDTKRYSSISMINLKYALMRIDNELDV
                     DSNLSYIFDNYNITEPCFVDDIEYLIDTFVINKATLLNRLGVEAFNRGLGDFSINMFM
                     TVLEMDRDDIDSIYNITSVLCELEEFDTAYNLIKNSSEKVQSESDIQEILCFIEGKKY
                     E"
     gene            52402..54516
                     /locus_tag="KOU88_001334"
     CDS             52402..54516
                     /locus_tag="KOU88_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBK3211236.1"
                     /translation="MNNDKICFITCVNDERLYEECLVYINSLDIPKNFSIETVALRGA
                     DSIASAYNKAMRETDSKYKVYLHQDTFIINKNFIHDILEIFKKNTDVGMIGVAGVKDM
                     PVNGIWWDSDKKAGKVYDSHTGKMDIYEFSNFEECFNEVMAIDGLIMITQYDVFWRED
                     KFDGWHFYDLSQSMEFRQNKYKVIVPKQNKPWCMHDSGVVNINNGYDEYRIKFVKEYI
                     NLDLYRENFYEFDKKKASTILKSNKHVMDCMKEELTEQLRLKNYKDVLGIVSKIAHFS
                     VFNHTGLYSCEECERALLECANNLPEIENTKLFTKKDLKRRKVLHVLSEGYSTGGHTR
                     LVKNWIEIDKDSVHSVVTTWQSDTLPDWLLKAINDSGGEVISLDLISDDYLKRAVALR
                     KIAYDWADIVILYVHMWDTIPVVAFGVDGKIPILHVNHYDSTFWLGTSIADIVIDFSE
                     TSQLITLDKRGIDKSEILPMPLKEKEVFSKSEVRKRYNLEDDVTIILTIASERKYNSV
                     NDINYFKIAKTLIENTDNTIIIVVGVDTENLYWKTLSNVTDNRVICFGTTANIDDFYK
                     ISDIYLESFMVGSHTSKLDAILYDLIPVKFKNEVSPIFTNMWNFIDKFDYKNIKEVID
                     MIRRYNTSEFDRDKIKAKQSEIKHFVIDKHCIEIKNYIDKIYNEVNHHKVKYDLYKND
                     EIEDYQLFVALYGYMVKNKNMS"
     gene            54525..55520
                     /locus_tag="KOU88_001335"
     CDS             54525..55520
                     /locus_tag="KOU88_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation glycyltransferase
                     FemA/FemB family protein"
                     /protein_id="HBK3211237.1"
                     /translation="MNNIHINKFEKSCEKNWDYFVENKSINGTFLQTRNFLNYHEEGK
                     FTDHSLIICKGEEILAVVPACETYEDGERIFFSHLGSTFGGIIIRSGFNDIRHVNAIT
                     NKLEIYLQEQNFDKVYLKNTSRIFCKEDTSLLEYFLFKNNYMFYDELSMFLELSKYKE
                     DILANFKYSKRRDFKYSLKNNLTFKRLYSDEDIVCFFNLLSNCLDSKGAKVIHSVEEL
                     LEFKNNRLKDIVEFYAVYIDDIMICGSMVFNFQERVYHTQYLASNSTYNKYYPMIFLY
                     YNLIKDALERNFKYLSFGISTLNRGKYLDEGLATFKEGFGSSAICNRTYYKNINK"
     gene            55612..56844
                     /locus_tag="KOU88_001336"
     CDS             55612..56844
                     /locus_tag="KOU88_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HBK3211238.1"
                     /translation="MKRLMILGSIKYFENIVMSAKREGIYTIVCDNRIDTPAKKICDE
                     AIDVDVFDFDKIKNIAIDKKIDGILTGFTDSLMKPYVYIANELNLPCVISCNQLESVT
                     NKAVMKNYFKNNGIPTTDYCIIESLKDLEKIQGLNFPLVIKPVDGYGSRGVYFVSNIE
                     ELIEKFEYSKEASQDGQVIIEEFYESEEIQGLAWVHNGESHVFYIGDRELVNIHTGRA
                     GKPDRLIYPSKYCFQYEEEIKSIYQNITQAFGIKNGPLYVQMLVGAYGIKVSEVMPRL
                     PGGCDYMAISQITDLDIGSLFANFSVNNEVNFDEIKKYNMHLSKCVYALPIYIRPGTI
                     KKINNIDKIENLDYVTQFLLLVKEGDTIGLYEDERQDCGRVYGVANNVFDANIKKKCI
                     HEMIEILDENNENMIENF"
     gene            56864..57808
                     /locus_tag="KOU88_001337"
     CDS             56864..57808
                     /locus_tag="KOU88_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase"
                     /protein_id="HBK3211239.1"
                     /translation="MKLITHEQIMSLNISQKQGYEWIKESFLTKKDCQLPPKISMVEE
                     GHVFYNVMPSLNHNHKIGGIKMVTRLPGRNPSLNSEIFLYNMEDAKLKAILDGNYITA
                     FRTAAVAALAIDTFAKKDFNTIAIMGLGVTASAIMNMLSYTLKDKNINIKLLKYKDQA
                     ESFVKKYEKNEQFSFEICDTHEELIVDSDVVISTVTYTDEYLSEFKWFKKGALLLPVH
                     VMGFGNVDYLFDKVYLDDYNHLKHLENIDRYKYSCEFYDVLSKQAKGRENDDERIISY
                     NIGLSIHDILFANKIYELCETLSCEEIELKEPKEKYWI"
     gene            57902..58309
                     /locus_tag="KOU88_001338"
     CDS             57902..58309
                     /locus_tag="KOU88_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxcM-like domain-containing protein"
                     /protein_id="HBK3211240.1"
                     /translation="MDKYNLIRFVSIGNEYIGNLVALESNKAIPFDIKRVYYIYDVPN
                     NVKRGFHAHKNLEQVLVCLNGSVKIKCYDGVKETIFNLHKNDVGLYIGTGVWHEMFDF
                     DEKTVLISIASEHYNEEDYIRDYKEFLKYLNNM"
     gene            58396..59487
                     /locus_tag="KOU88_001339"
     CDS             58396..59487
                     /locus_tag="KOU88_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS family aminotransferase"
                     /protein_id="HBK3211241.1"
                     /translation="MLVKFNNLLKQFQTHKEEYEQKIKDVMESGYYILGNEVKHFEEE
                     FANYVGSKYCVGLASGLDALIIAFRALGISEGDEVIVQSNTYIASVMGISINGATPVF
                     VEPNEYYNIDSSKIEEKINSKTKAILVVHLYGQASNMKDIQELCDKYNLYLIEDCAQS
                     HGAKYDGKMTGTFGDIGCFSFYPSKNLGAFGDAGAIVTSNEEIADKVKILRNYGSEKR
                     YYNKFVGYNSRLDEIQAGLLRVKLKYLNEIEIEKSKIVDRYLNEINNPKVILPKIENN
                     CTHVWHLFVLQVEKRDTFMEYLKKNGIESIIHYPIPPHLSEAYAYLGYKKGSFNIAEN
                     YSDKVVSIPLFIGMEDEEVSYIIKIINEY"
     regulatory      59796..59886
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            60296..60613
                     /gene="flgB"
                     /locus_tag="KOU88_001340"
     CDS             60296..60613
                     /gene="flgB"
                     /locus_tag="KOU88_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBK3211242.1"
                     /translation="MNTYDIIKMGLDATNLRSQTIANNIANINTEGYKRHYVTFEETL
                     NDAMPKIEEKTDNSKGLRVDGNNVDIEEEKVNQAMTTLQYNALISFANGKIAMTKSII
                     SGR"
     gene            60621..61025
                     /gene="flgC"
                     /locus_tag="KOU88_001341"
     CDS             60621..61025
                     /gene="flgC"
                     /locus_tag="KOU88_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBK3211243.1"
                     /translation="MSVFSGMRISASGLTAESLKMDIISSNVANINATRGPNGEAYRR
                     KVVSFEENYDNKLGMLGVKVTSVEDDKSPLKKVYDPSHPDAKPNGYVEYPNVNILVEM
                     TDLITASRAYDSNVDTLNAQKSMISKALEIGK"
     gene            61035..61349
                     /gene="fliE"
                     /locus_tag="KOU88_001342"
     CDS             61035..61349
                     /gene="fliE"
                     /locus_tag="KOU88_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBK3211244.1"
                     /translation="MPITQINNLMQGAKLDNLIGETKPLTLNKEEKKNFEDVIIDTID
                     KVNFQQVTADDMKEKFIKGEDVSMHEVMLIGQEAQLSMQYLIEVRNKIHDAYQEMNKV
                     QI"
     gene            61374..62924
                     /gene="fliF"
                     /locus_tag="KOU88_001343"
     CDS             61374..62924
                     /gene="fliF"
                     /locus_tag="KOU88_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBK3211245.1"
                     /translation="MIASFKNKIKEQVAKSRTKISSLKKGTKIALGIGVIAICLALVF
                     TAISASKNKYAVLFSELDVQDAADISAELESKKIDTKVKGSTIYVPRTEVDKLRLELA
                     PSLTSGSKGFALMDDSSSIGLTDEEFQIKKQRMIQGEIEKTIKSFPQVEDTRVHITFG
                     ESSVFEKEAVPGSAAVYLMLKPGTTLEKNQIKSVMALISGSVTNIPEKNVQVIDNKMN
                     LLSEGILEDENVNENNQPINSGISVDKNKASEQALNKQLEKSILEILEPIFGKGKVKA
                     TVNADLSFDTAEKTEIKIDPDKVAIKETRSKNSSKSATNNVQGVDANMNNQGNNNGTN
                     TEDSLDESFEYETGKIETHTIVAPGELNRLTASVAIDGKIAKGVQADVEDIVNNAIGM
                     DGARGDTLSVVSMVFDPEGKKEAKQELEEIKKEGFKKNIIKAVIGVVAVVAIGAIGYL
                     IYKKRSEREDMDYEDEDYISKSDSVDRKDNPLLGDDPELTLEEAVKMYAEEKPDQVTE
                     IIKTWLNE"
     gene            62937..64007
                     /gene="fliG"
                     /locus_tag="KOU88_001344"
     CDS             62937..64007
                     /gene="fliG"
                     /locus_tag="KOU88_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBK3211246.1"
                     /translation="MSTEITNVNAFDLSDINESDKKEKIEGEGLKKAAVLLMTLGPNV
                     SSDIIKSLPDKQVQKIGLEIANISSIASKERREILKEFVEINRAKDYVIEGGLEYARE
                     LLSNALGNAKANKLLEGISINTSTKPFKHIIKLDVKKILEILRNESAQTIAVLLAHME
                     PENGAEVLSYLDFDLQNEVAMRISSMGSISPEVIKVIESSLEDKLHSMSGDDFKDYGG
                     VSTLVQILINSDRKTEKNILGTIEEQDPDLAAQIKSHIFVFEDIVKLDDISIQKVLKE
                     VTMKDLVYALKGVDDEISDAIYRNQSSRAAEALREEMEMVGVIKVTQVEAAQQKIANI
                     VRKLEREGAITIVRNFGGDFVE"
     gene            64000..64731
                     /locus_tag="KOU88_001345"
     CDS             64000..64731
                     /locus_tag="KOU88_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBK3211247.1"
                     /translation="MNNKIIKSKKALYKGVLDLTIIDKVRVGESNVNKENDCRFRDEV
                     IKEAIESAEIKKNEILEEAKMNAQNIEKQAYEKGYSQGQKNGYEDGYKESYNEYTQKA
                     KDEADFIKNQADLILLQANEKMTEYIKEKNKEIVRLAINMASSVLKKHFEDEESMSDL
                     LKQIIQDYEGSSSFIVRCNSFYKDNIEKEFELFKEETSLKSSVFVIADDSIDKGNAII
                     QKENGRIIVGIDCAMEKLKEELLGE"
     gene            64735..66054
                     /gene="fliI"
                     /locus_tag="KOU88_001346"
     CDS             64735..66054
                     /gene="fliI"
                     /locus_tag="KOU88_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein export ATPase FliI"
                     /protein_id="HBK3211248.1"
                     /translation="MYKTDISIDFDKINKKIENLELTISEGRVKKIIGLTVEVEGIKA
                     FVGELCVIYNQVNKPVNCEVVGFKDKEVILMALGELTLIAPGCKVISKGIPLSVMCSD
                     NLLGKVLDGLGNPIDNSDAVLGDRYNLNNEPPDPMKRKKIRNIMETGVRAIDAFTTCG
                     EGQRIGIFAGSGVGKSTTLGMIARNAKADVNVIALIGERGREVLDFIDKDLGEEGMKK
                     SVVVYATSDKAPLVRLKGALTATAIAEYFRDQGKKVILMMDSVTRFAMAQREVGVAIG
                     EPPAQKGYTPSVFAILPKLMERTGTSDKGSITAFYTVLVDGDDFNEPIADTTRGILDG
                     HIVLSRDLANKNHYPSIDVLNSLSRLMNEIASKEDIKIASFARDMLAEYREAEDLINI
                     GAYASGTNKKIDEAIYYHEHIINFLKQGINEKSSFNETISSLRGIFE"
     gene            66086..66532
                     /gene="fliJ"
                     /locus_tag="KOU88_001347"
     CDS             66086..66532
                     /gene="fliJ"
                     /locus_tag="KOU88_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012815984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export protein FliJ"
                     /protein_id="HBK3211249.1"
                     /translation="MELDKNFKFRLQKVLDLKIKDEEEIKMEFAKIQQKKIDIETNLE
                     NLESNYSKYSIGKNNDSVQNQKITINYLLALNNSIMDLSEKLDKSTNELEKARKQLIS
                     KQIERKSLEKLKEKKYGQYYKEEQLKEQSTNDEFASMSYLRNRQVL"
     gene            66560..67765
                     /locus_tag="KOU88_001348"
     CDS             66560..67765
                     /locus_tag="KOU88_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-length control protein FliK"
                     /protein_id="HBK3211250.1"
                     /translation="MKIQADSYNIIKDIGNRKNSSKNKNIKNDKFEDNLYKTTDHKKV
                     KDRRETSKQNVSSDRPENSDNECHLDEDKSNHLEDENTYEKDCSNNNEALQQLLNLLK
                     ENYKKDKDINTILNNIKKLSISDELKQELKLNKNILNKIANQNSELNKANINNSNDIE
                     NLDIVKLRELLEDNANKDIEVITKTTENDTKNIDLYSFDSNRMDNLNSNKQKDDSSDI
                     LEKLAGVNGNKSGNFGQVINKNVDMNKIKNDNVNLKQIESNVMDDSIKAIKHMKTNDI
                     QELTIKLRPKELGDMNIQLLKDGESMRAVVTVFNKDVFDSINKNIADLKQHLELTNVN
                     IKDVSVQMHSDNTNTSDTFDKAFEQQNRQNNQENMSKKNTNDKHNNVVIEDDIKENTI
                     DDDRVDLLA"
     gene            67783..68391
                     /locus_tag="KOU88_001349"
     CDS             67783..68391
                     /locus_tag="KOU88_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlgD"
                     /protein_id="HBK3211251.1"
                     /translation="MYGIATALAGTQGNYRSNNLSQLERNINDIANKQVRSKGNQTVT
                     DNGTPIIGQGDDADKDLFMKILVAQMGNQDPMNPQDPTEYVSQLAQFATLEKMSAMNE
                     KLDVLLALSNSTLINSALSMATSLIGKEVEVSGEEKEDENIVGVVKSTYIKDGEVHLE
                     LEVDGSDKTVGVKYEKLLKIGEVDENSGEENDSSEHESPEEA"
     gene            68418..69401
                     /locus_tag="KOU88_001350"
     CDS             68418..69401
                     /locus_tag="KOU88_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein"
                     /protein_id="HBK3211252.1"
                     /translation="MIKAMYSGVSGMKANQTKLDVIGNNVANAGTTSFKKSSARITDS
                     FYQTVLYASAPTAALGGTNLGQVGVGSKISSINKDMVQGNVQPTNRPSDLMIDGDGYL
                     PVVRQGTVMYTRDGSFNLDTGFKAADGALKNIKGGRLVNGDGYMLQGMIYDGEYKADT
                     GEFVKKGDAKGKEPIVIPLQSISPKDGTVQNVLEYNISKDGTVEFLLSDGQRTQFVYD
                     IPDGAKVGDTPAGIDKLKGTIQKVQTYAFQNPAGLDAEGGNLFKPSANSGDPQIAGAT
                     GTIIQGAIEASNVDIAEEFTEMIIASRSFQANSKIISTSDEILQEIINLKR"
     gene            69414..69617
                     /locus_tag="KOU88_001351"
     CDS             69414..69617
                     /locus_tag="KOU88_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar FlbD family protein"
                     /protein_id="HBK3211253.1"
                     /translation="MIRVTDLNGRKYILNSDLIVRIDSVPESRILLTTGEKNLVKESV
                     DEIVDKVIKYKRKINVGYIRSEK"
     gene            69617..70435
                     /locus_tag="KOU88_001352"
     CDS             69617..70435
                     /locus_tag="KOU88_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MotA/TolQ/ExbB proton channel family protein"
                     /protein_id="HBK3211254.1"
                     /translation="MKKTDSLTFIGLIVSTVLVLVGAAKGSSSGLKNFFDVSSILITV
                     LGSFGALMITFTIDDIKLIKNALQYSFKTMSVSKLDLLEQFKTLSKKARKEGLLSIES
                     DVMGIEDPFMKKGLELCIDGLEINEIRSILELEIDSVEDTNNRYSKLFKTWGTFAPAF
                     GMLGTLIGLIQMLADLTSPDLIASGMGKALITTFYGSLLANIALNPIAYNIDEKTEKE
                     IYVKEMMLEGIISIQSGESSIVVEERLATYLSNNEKLEIMKSNKNTERAMSNGA"
     gene            70425..71120
                     /locus_tag="KOU88_001353"
     CDS             70425..71120
                     /locus_tag="KOU88_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBK3211255.1"
                     /translation="MARKKNKKKDEINPDAWLATYADTITLILTFFVLLYATSVVDME
                     KFKNIADALKGQFSGTSIFSTGSSTSEKSPIDSVLVDKNDKSNLEQDLKDKVNNSNLQ
                     NSVTVKDDSRGILLELDDSILFDSGISELKVDSKATLNKVYDMIKMMKNKIVIEGHTD
                     NVPVKSSTHESNWDLSSSRAVSVVRYFVEEKGMDPRLFSATGCGEYQPLVSNETAKGR
                     AENRRVNILITID"
     gene            71132..71575
                     /locus_tag="KOU88_001354"
     CDS             71132..71575
                     /locus_tag="KOU88_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated FliL family
                     protein"
                     /protein_id="HBK3211256.1"
                     /translation="MFKNKKIIIIILILIIFSAGAGFFILGEGGNKQVDKIAGLFIPT
                     GKGKDEVKTENLDLEEMVLKLADEGVRYLKVSITVSYDSSYKDIEKNTPLIRDNIINC
                     FMAKRADDFTADNLKNIKEEIKNTLNIQLGENVIQNIYFTNIVVQ"
     gene            71590..71964
                     /locus_tag="KOU88_001355"
     CDS             71590..71964
                     /locus_tag="KOU88_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliZ"
                     /protein_id="HBK3211257.1"
                     /translation="MILYLLKILICIPIILILIVLSLKISQGTLLKKYNDKYVKILDI
                     VNISKNNSIIILKIGEEGCIMASSSSSMSKIKDLTKEEVLKIENDIKERNFKIQDFKM
                     ERIKKKYDFSRYIGKFTKKEDK"
     gene            71965..72630
                     /gene="fliP"
                     /locus_tag="KOU88_001356"
     CDS             71965..72630
                     /gene="fliP"
                     /locus_tag="KOU88_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425215.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBK3211258.1"
                     /translation="MELLSKLPLADVPYTSSMQLFLFLTALMFLPFVMFMMTSFVRIV
                     ISLSFLKSALGAQQAIPSQILVGLAIVLTIFIMRPVLNEINEKALQPYMKEEVTMEEA
                     MKEAEGPIKEFLLTQTRQTDLDLFVEQAGLKEKKLTRENIPLSVVVPAFAISELKTAF
                     QIGFLIYIPFLIIDLVVASVLMSMGMFMLPPVMISLPFKLLLFVMVDGWNLIVKTLIL
                     GFG"
     gene            72643..72912
                     /gene="fliQ"
                     /locus_tag="KOU88_001357"
     CDS             72643..72912
                     /gene="fliQ"
                     /locus_tag="KOU88_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBK3211259.1"
                     /translation="MSEFMIMSVLKNGMFTGAMIAAPVLIVSLVVGLLISVFQATTQI
                     QEQTLTFVPKLIAILLVVAIGGSWMLHTLISFTSEIFNMISLITK"
     gene            72924..74738
                     /locus_tag="KOU88_001358"
     CDS             72924..74738
                     /locus_tag="KOU88_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused FliR family export protein/FlhB family
                     type III secretion system protein"
                     /protein_id="HBK3211260.1"
                     /translation="MIFVFIRIVAFFGTLRILFPAGTPALFKSLFAIIISILISSTMQ
                     IEYATNIDNIVLFTLYSVNETITGIMLGYITNLCFYSIRMAGSMMDQQMGLSMINMFD
                     PNSMTQTTLIDNLMNWTALMIFFNMDGHHVLIRGIRYSFELIPIGKPFVDNNIDYIIN
                     IFVQCFLTGFKIAIPIVLCLLMADFILGLISRSVPQLNVMIVGMPLKILVGIALFIIS
                     IPLIVNQISHLLSQIPKMYEGTFALAPMFFMGSADKTEEATPKKKGEQRKKGNIAKSR
                     ELPVAMTLLAFTLLVPTLFSYVVDTLKSSLNYFLSLDFYMNINYSNLEKLVIAGLMDF
                     FKIFLPIAIPFLVLGIIANLFQVGILFTGETLKPNLSKLNPISGFKNMFSMRSLSTLI
                     KDTAIISILAYIGYTFFQDNYLDILKLGNIYLPTLMYTVKDLVYSILSKICVAMIAIA
                     VADYVYQRYSHKKQLRMTKQEVKDEYKNSEGDPEVKAKIKQKQRQISSQRTMQAVPSA
                     TVIVTNPTHLSIAVRYEKGKDQAPVVVAKGADYLAFKIREIAKGNDIPIIENKPIARL
                     LYKQVEIDQEIPEDMYQAFAEILVAVYKIKNRYKVPKR"
     gene            74747..76822
                     /gene="flhA"
                     /locus_tag="KOU88_001359"
     CDS             74747..76822
                     /gene="flhA"
                     /locus_tag="KOU88_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBK3211261.1"
                     /translation="MNKFNLKENMDVIVAFGVVGIVLMMIVPLPTFILDILLAINISL
                     SVLILLMTLFTTNVLDLSIFPTVLLVTTLFRLGLNLSSTRLILTQGYAGEVIEAFGSF
                     VVGGNYVVGIIIFLIILIVQFVVITNGSGRVSEVTARFTLDAMPGKQMSIDADLNAGV
                     IDDKTARKRRKELQQEADFYGSMDGANKFVKGDAIAGLIVTAINIIGGIVIGAVMLNM
                     TLMGAAQTYVRLTIGDGLVSQIPALLISTSAGIIVTRASTDENFGGLVGKQLTAIPKA
                     VMMTGCVLIVLGMMPGLPKPAFFSLGIGAIAAGYFLGREKKDTLEDLEFEKPDMVNPD
                     KNEVEDVTNLINVESIEVEIGYGLISLADESAGGDLLQRIASIRRQCAIDMGIVVQPI
                     RIRDNLQLNPNQYNIKIKGNVVGGYEIMPNMVLCMDPMNQGFSIFGIKTIEPTFGIEA
                     LWIESDKVEDAELKGYTVVDSSTILITHLLDIIKSNAHELLGRQEVKTIIDAARENYS
                     AVVDELIPDLMTLGEIQKVLKNLLREKVNIKDRVTILETLADQSRNTKDIELLTEYVR
                     IALARSICNNLVDEDKAIVVATLSPETEELVSNNLQRSVNGTYPAVDPENTNKIFESI
                     QEVMNNVYFNHNIPVIVVSPKIRAPFRKLVEIVYPNLTVLSLNEIPNDIKIKAEGVVS
                     IYDDEKVYS"
     gene            76797..77813
                     /gene="flhF"
                     /locus_tag="KOU88_001360"
     CDS             76797..77813
                     /gene="flhF"
                     /locus_tag="KOU88_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhF"
                     /protein_id="HBK3211262.1"
                     /translation="MMTKKYTANTIQDAMNLAKMELGDNITLIDKKEVRKSGIRGIFS
                     KKDIELTIGWEKKDNLEQKDLKREIEQLKSIINNMGFDNKNDNDIDKICKNLLNLDLN
                     QEIVEFIKADLQEMKFNGIDTSKNLVESLKKKIKIENQAINGKIALVGPPGVGKTTTI
                     AKLAAKLVFEENKKVGVITIDTYRIGAVEQLKIYTDIMNIPFKGVISPDEMELALDAM
                     KDCDVVLIDTTGRGYKNSMQILEIKNLIDKAETDNIHLVLNCTTRESDTKAIIDSYRN
                     VNFKSLIITKLDETITYGSIFNIMNYAQKPISYITTGQNVPDDIIKPNEDKIIRLLLG
                     VESI"
     gene            77810..78688
                     /locus_tag="KOU88_001361"
     CDS             77810..78688
                     /locus_tag="KOU88_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MinD/ParA family protein"
                     /protein_id="HBK3211263.1"
                     /translation="MIDQAQILRKMAMEKRGSDEIIVENENMPKIITIASGKGGVGKS
                     NLATNLSICLTKLDKKVLILDADIGMSNIDIIMGVNVKGTIIDVINGEKNIEDIISQT
                     KYGVNVISGGSALNHIEDFTEAQRNKFIHSIEQIHNVDFIIIDTGAGMSKSLLSFIYC
                     STEFFLITTPEPTSLTDAYSLLKAISNFGIKKSANIIINRVIDLEEAKSTYKRIKMVV
                     DKFLNLNLELYGYIIDDKKVSLCVKKQIPFILEYPTSIASKCIIAIAKRMVSQSREDI
                     VDNKSFLRKMFSIFKS"
     gene            78702..79403
                     /locus_tag="KOU88_001362"
     CDS             78702..79403
                     /locus_tag="KOU88_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliA/WhiG family RNA polymerase sigma factor"
                     /protein_id="HBK3211264.1"
                     /translation="MNREELIKENMPLVKSIARKFFIPGKGFEYQDLVNSGVIGLIDA
                     INKFDAEKGAKFSSYSYIKIKSAILDEIRNQSPISKHNLTKVNKYNRVVEKLQSKLLR
                     EPTSYEIAKELKVSEKELHDIESNIDMLNIVSLNYVIFEDTNETVQDVISDREEEAPE
                     NIIEEEEKLEILSKAISNLNEREKLILSLYYYEDLNLKEIGKVLGVSESRVSQLHRKS
                     IRNLRNKIKELKYSI"
     gene            79419..79841
                     /locus_tag="KOU88_001363"
     CDS             79419..79841
                     /locus_tag="KOU88_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBK3211265.1"
                     /translation="MIQIILIVVSILIIVTIVINLHKESKNKDNRYFDKIFEQEYEAN
                     DRLIIAEKRRFFLDKVLAEIRSNNHIKVYENYNLIKANEERKENIFIESKKEVRQENE
                     LSLKVKHLISSGYDDVEICKMLDIGKGELSLIRSCYKI"
     gene            79826..80011
                     /locus_tag="KOU88_001364"
     CDS             79826..80011
                     /locus_tag="KOU88_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein"
                     /protein_id="HBK3211266.1"
                     /translation="MLQNIRILLCDKKVFLGIGIGILISTLCIMLFSNNDMSKAEIEK
                     KARALGMKYTSEMKVLE"
     gene            80052..80825
                     /gene="flgG"
                     /locus_tag="KOU88_001365"
     CDS             80052..80825
                     /gene="flgG"
                     /locus_tag="KOU88_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBK3211267.1"
                     /translation="MIRGLYTAVSAMITNQQKQNVVVNNLANMDTNGYKSKQLLTKSF
                     DELKLEGYNNYANGTKQKQIIGDISPGISMDETITNFNQGPIKTTDNKMDVAIQGKGF
                     FLVSDAAGNQFYTRNGNFRTDNQGDLITSEGYYVLGTNTATGAVGHINVGNQKFEVAK
                     DNTISLDGNAMYKFNIVDFNNYNNLKKEGDNLYSGGGAMKVNNALTIQSAIESSNVDM
                     VSEINNMMTISREYEANQKIIQAMDSKLAKIASEIGSVR"
     gene            80846..81607
                     /gene="flgG"
                     /locus_tag="KOU88_001366"
     CDS             80846..81607
                     /gene="flgG"
                     /locus_tag="KOU88_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgG"
                     /protein_id="HBK3211268.1"
                     /translation="MYTMFYTSKTALSANQSKLDIISNNIANSDSTGYKKINMEYSDL
                     VDEVLNRPSYPTNGNDISTGTGAKATAPMRNYEQGALAPTDSKSNLAIDGEGFFRVIR
                     KDGTYAYTRNGGFNVDALGKIVDDNGNILDVQFDAGYNYNNTNIDSTNLTVSRNGELF
                     VDNKKIGKINLYQPIGTQNFISEGDSLFVATDAAQIKQVEKVDIVQGYRERSNVSLQE
                     EFVDLIATQRAFQMNSKGIKTADEMWQIANNLRAK"
     gene            81630..82511
                     /locus_tag="KOU88_001367"
     CDS             81630..82511
                     /locus_tag="KOU88_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBK3211269.1"
                     /translation="MNDMKEYDFGKPQSYSRENLTCLNFLLAEFCKKYKNYIIYELKC
                     NSSMVVDSIDQVNYQTFLDRVTSSCVVVQNAMEPVMKNFSFRIDRSVADMWIDITSGG
                     TGVVKDNDRELTELDKKVLLHLMDDLVRNMHLFEGFENIQVLDTHTHINLPQLCSPTA
                     PVCVVDLKVLNDNEYIGSVSLCFPYNGLEALLESISVIEFFDNDIGDDSEEFTKKIYN
                     SVSNIELSVIAEIGKVSINVEDLLKLEVGDVIVTNKKINDYIDIFVENSKSYTATPGF
                     ISSKKGVKINDAVGKEV"
     gene            82514..82888
                     /locus_tag="KOU88_001368"
     CDS             82514..82888
                     /locus_tag="KOU88_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FliM/FliN family flagellar motor switch protein"
                     /protein_id="HBK3211270.1"
                     /translation="MDNSNLISDEEAKMLLNDKVESEVDGDDELALDVSEVNRNNIQR
                     ILDLKLELSVVIGRTKMTLRDILNLHKGSLIELDTLADQDVEILIDNKVLAYGKVVVV
                     DLNFGVKITSIVSEEDMVKSLV"
     gene            82920..84323
                     /locus_tag="KOU88_001369"
     CDS             82920..84323
                     /locus_tag="KOU88_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK3211271.1"
                     /translation="MVLILNLNDIKKDILKLNKKDSCSLYNESINNINNNCISSGLKF
                     LKQARDLNPDDVDILNLTGLVNLLKCNFDEAVESFYKSSLCEKTALCEKYINMLTSEE
                     FLIFFERYNQLIRLINRGMYKEAIQGFKLITEQYCDLIEPYELLALLYDKEEEYIKFD
                     ECLEVLKIIDKENYLLNQENNTLDMYNSANIQTKSNIKVDDYKNEFLHKSSSNHKIND
                     YNDVTKEKSSSKNQKSSDSNKKKSIKKNKYLYIAIILGILLVGQSIYSSYKMNNLTDK
                     ISKNNETKNEESIDSNLTKKENNIEENEDMSKASNINKSNKNINKEDDVKSKKNTVEN
                     EDDKDSDLFTEDELMSKANTLKSEKKTKSSIQLYKKVADIGENKGNTSEATYQVAILS
                     EKLKDYKTAEEYYKMYVENYSEKDAYFDESYYNLGMMYYNNGDLKNSKLTLKKLVNKV
                     PNSMYNNSKVKEILKEE"
     gene            84439..86376
                     /gene="htpG"
                     /locus_tag="KOU88_001370"
     CDS             84439..86376
                     /gene="htpG"
                     /locus_tag="KOU88_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBK3211272.1"
                     /translation="MEFEKGSISIHTENIFPIIKKWLYSDKDIFIRELISNGCDAVSK
                     HKRLVSLGEISENKSSDYKITVSVNKGEGTLKFIDNGIGMTEEEIKKYINQVAFSGAE
                     DFFNKYKDKMEESNDIIGHFGLGFYSAFMVSKKVQIDTLSYTEGATPVRWISEGGTEY
                     EISESDTRNDRGTTITLFIDDDSKEFLDEFTVRGIINKYCSFLPVEIYLEDVERLERE
                     AKEAEEKAKKQKEDGKEEIVDAKVIEPLNDTNPLWLKSPKDCTDEEYKEFYRKVFNVF
                     DEPLFWIHLNVDYPFNLKGILYFPKLKNEFELTEGKVKLYNNQVFVADNIKEVIPEFL
                     LLLKGVIDCPDLPLNVSRSFLQNDRDVSKISKHIIKKVADKLKSLCKNEREEYNKFWD
                     DIQIFIKYGCLKDESFYEKVKECILFKTIDDEYITLQDYLEKCKDKHENKVFYVSDKE
                     QQSQYIKLFKEYDLSAVVLNSSIDTHFISFMEYKENGVKFNRIDADLSDVLKDKNENK
                     DSEENKEEIAKIEGLFKEAVGERVKHYSVEGLKNEDTPAMVLVSEQSIRMAEMQSRFA
                     GMDLGMNFEEEKTLVINENSPIIKKLVSLKDDEEKKDKITLICNQIADLALLSNKELK
                     PDELDSFVQRSNKLMSLFIEL"
     gene            86764..87894
                     /locus_tag="KOU88_001371"
     CDS             86764..87894
                     /locus_tag="KOU88_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBK3211273.1"
                     /translation="MNFNYNLPVNILFGRGRINDVGKEVSKYGKKVLIVTGKNSTKKT
                     GLLDKTIDLLKDSKIEYEVFDRVEQNPLITTIYSGVEIIKSTGCDCVLGLGGGSIMDA
                     AKSIAFSYKNSGDLNDYIFGIRQGEEALPIILVPTTSGTGSEGNCFAVLTNSETKDKK
                     SIKKNSMYAKASIIDPELMVTMPKHIIASVGFDALAHNMEAYLSNGRNPLADVQAIYG
                     IELISENLIKVYNDVNDLEAWEKITLASTIGGMTIGTAGTALPHGMEHPVSGLRDVMH
                     GKGLAALTPTIIESSWDSDIERFGNISKVLGGTCAEDCSDAIRNFLKKIDLDIKLSDL
                     GIEKSDIDWLTDNCMKISVANIKRHPKYFNKEQIKEMYHKSL"
     gene            88121..89143
                     /gene="splB"
                     /locus_tag="KOU88_001372"
     CDS             88121..89143
                     /gene="splB"
                     /locus_tag="KOU88_001372"
                     /EC_number="4.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore photoproduct lyase"
                     /protein_id="HBK3211274.1"
                     /translation="MFNPKRIIFEKGTLDTDVGKKIYNKFRDNKDVEIINISSNRIKE
                     HIPGENLYEQYRSGKQTMVVGIRKSLKFQTCKPSANYQLPLVSGCMGRCEYCYLNTQL
                     GDKPFIRVFVNVDEILEQTKKYIEDRKPQVTIFEGAATSDPVPVEPYTNSLKKTIEFF
                     GREEKGRFRFVTKYSDVDSLLDAEHNNHTEIRFSINTPRIINEHEHYTASANKRIESA
                     VKLARAGYQIGFIIAPVFLYEGWKEEYKNLIISIKEALPKDFDKKIIFEVISHRYTTK
                     AKNRILEIYPDTLLPMENEDRKFKYGQFGYGKYVYDKEQLDDMKEFFLKEINGVFKNS
                     LIKYII"
     gene            89325..90236
                     /locus_tag="KOU88_001373"
     CDS             89325..90236
                     /locus_tag="KOU88_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK3211275.1"
                     /translation="MHAWESIQITLDLIEANLSEEISINELANKANLSPFYYQRLFKR
                     LVNKTVMEYIKLRRLARASEYLAEHKNRILDVALNFGFASHETFTRSFKKAYGLTPEK
                     YRANPVKLNHFIKPELILNYAMVDEGVPLIADDIVIEVNRKTLSNPRTFVGIEIEVPI
                     CQLVGGETTGIAIVEELWMKLGSQRHNIPNQIPGGNEFAALYMGNAKEGNCMYMAGVE
                     VESGTSVEGYSTFELPAKEYLVCGFEAENFNELVNSAVFKADKFMERWMKKHNLTTTD
                     FAIEMYYPTTPEAAYLEHWIVPVPIEQ"
     gene            90251..90667
                     /locus_tag="KOU88_001374"
     CDS             90251..90667
                     /locus_tag="KOU88_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBK3211276.1"
                     /translation="MNWQDAFFQDTKPTFEQINEFINNPLWDKLNKTLVSTYNVEPKL
                     EYSKCSMQRGWNVKYKKRGKSLCTLYPQEGYFKALVIVSESNRVEVDLFINTCCDYIK
                     KIYNEVNFFNGSKWLMIQVDSLLVLNDMLELIKFRA"
     gene            complement(90767..91159)
                     /locus_tag="KOU88_001375"
     CDS             complement(90767..91159)
                     /locus_tag="KOU88_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211277.1"
                     /translation="MSINTEKNITKNVEELTCPIRYALDIVGGKWKLPIICMLAVENP
                     IRYSSIKRKLDGITNTMLAQSLKDLESTGIVHRKQYNEIPPKVEYTLTSKGKSIVPIL
                     QQFANWGATNMQEKNTCGLSCKECRKIK"
     gene            91300..91695
                     /locus_tag="KOU88_001376"
     CDS             91300..91695
                     /locus_tag="KOU88_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBK3211278.1"
                     /translation="MKALEFLNKARVYYLATVDENNQAHVRPLGFVMEYNGKLTFCTS
                     NQKDMFKQLIFNPKVELCCIDQNLNTLRILGEAVFVTSKETQAKALEIMPSLGQMYSV
                     GDGKFEIFSIDKAKVSCCSMSGKKIDVEL"
     gene            92098..92304
                     /locus_tag="KOU88_001377"
     CDS             92098..92304
                     /locus_tag="KOU88_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211279.1"
                     /translation="MSKYSSLWEYVKKNNSQSFKLTFEEIKDIAGIEIDHSFLKYKKE
                     LNEYGYQVGKISLKEKTVIFDKIG"
     gene            complement(92461..93192)
                     /locus_tag="KOU88_001378"
                     /pseudo
     CDS             complement(92461..93192)
                     /locus_tag="KOU88_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435948.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        37250 a         9959 c        16244 g        29928 t
ORIGIN      
        1 agcattggat tttattaata gatagataaa agttatcaac tagaagtggt tgtttgttgt
       61 gataactcta ttattgtaat ataatgtaaa tatattattg tgataatgga ggatttatgt
      121 atggatgcat tggtttatga gagatttgta agagcagctt ttagtattaa acttaataac
      181 ttgattaata gaagcgaaga tttaggtgga ttggctgaag ctgatatctt tagagcagca
      241 aataatttac atgaattaaa tgagataaaa ataggtactg ggtatgctat tgcaatattt
      301 aataatgaga tattagagtc ttgtaatgtt tctgataatg atagcaatag aatgattgaa
      361 ctatttgata gaagtttaat tgcaacttct agggaggaaa tattggatat tataagagaa
      421 tatgaaactt atagaggacg atatcttact tttaattgga agagatagaa tgtttaagtt
      481 aggaagtagt aattatagtt agttattact ttctttcaca tatttttatt atttcaataa
      541 gattatttcc aaataataat ttattcaatg ataataagta gaaaataaaa ttttgaatca
      601 atataaaatt taatgaaatg aggtagtaaa atcatggata aaaaaataga catagcgaag
      661 tttatagtaa atagaattga ttactatatt gaaaaatcag ataataaagc tagtttttta
      721 ctattattaa atagtgcaat tataggtttt ttattttcag ggaaggaaaa aataatgaat
      781 cacttaagta taagtaatat cagatgttta gagatgctat tttacattgt tatattatgt
      841 atatttgtta tttcaattta tttttcgatt atggttttaa agccaaggaa ttctaaaata
      901 gaaaatgaat ataaatctat tttttattat aaagagatag catctttaaa taatgaacag
      961 tacaaagaag catttgaaaa tgcatttaaa gacgaagaaa acttgattaa tgatgcactt
     1021 gttcaaataa aagaattatc tttaatctgt gataagaaaa tgtataatgt aaaaaagtca
     1081 gtagaagctt ttattttagg tggtattata ttgtttatat atatacttgt agtagttttt
     1141 aatgctattt agaaaatgtt ttatttggtt agtattcctc tatgaagata gaatcaaatc
     1201 atagaagaat actatttaca tatttgtaga ttcttgtaat tgattttcat ttaatttttt
     1261 aaatgctagt tttaaagttt ctttaaaatc aggtactgtg ttttcattaa aatcttcaag
     1321 ttcatcctct cctatccatg caagttcatt atgttttgat gtgggttcaa atttagaaat
     1381 atcataatca tttattattt ctgcgagagt tataatgcct ttgtgtaaac catcactttt
     1441 tttaacttga taaattgcta gaggtatagg ttggcaatca tcttttcttg tgcaatcagt
     1501 aataggttca atgtttatat taaaatcttt ttcatattca tctttaatag tatttataat
     1561 tgaagtttct agacttgcct tagcacaacc aaattcccat ttactcgcat tattatttct
     1621 attatcactt cttttcgcaa ttaatatttt tgaagttgat ttattataac aaaccgcaac
     1681 acagtgtaat tccattaaat ctacttttat atagtcttta tctattgtat ttttatcata
     1741 actggggttt gttttagaaa ttacgtcacc tattttttca atcttatcac taaggtttct
     1801 gtctataagt attttatcca aagccttgtc tacagaatta aacataaaag aatcaattag
     1861 taatttactt tctccttttt tattaaaaaa atattctcga accaattcat tttcttctat
     1921 ttcatcaaaa gaaaaactat catcaaattc tatatcatta ttttttcctt tattatgata
     1981 ccaaatgata gggtatagtt tatctttcca gatacccttt aattttttat atgtaattat
     2041 atgtaattta gataaaatat cagtttttct tgataatata taagctagtt caaaactaag
     2101 aacaagtctt tctgggcatg tttgctttga tattctgaaa ccagcatcaa tatcatttcc
     2161 taagaactca aatattttat aattattgga taaatcgtac atagcagaaa tattttcata
     2221 ttgttcatta ttttctaaag cattaaaatt aggatttctt gatactatag caatccaggc
     2281 cgctcctttt aatgaaataa tattttgaag tttcattaag tatttttcag attcagaaaa
     2341 tccttctagt gtagagaata tattaccact ttttatatct ttagcagtgc ttgttaaaat
     2401 atcaaagatt atatctatgt atttataaat ttcatcataa ttttttagta cgataatgaa
     2461 aattacctca tcaccaagaa ctctccaaag ttgtgcttta aggttttcat aaactctata
     2521 ttgtaactta cgaattatat gtgataatac cttagcccat ccgctataat ttatattttt
     2581 atataatgat gaattagcta tatcaaaaga aaagaacaaa atcacttctg gatgattagg
     2641 ttctttttct ttttcataaa tatcagtatt aatattttct tgaagttttt ccttatactt
     2701 tttaagatta aaagcgtttt cgtttttagc tgaattatga acattattta cattttgagt
     2761 tttatattct ttatcatcta ccattgtaaa tatcctaacc atttccctct attagatgct
     2821 gcataagagg aaacattaaa gtattctgca atttttgaag tgtcgacctt attacctact
     2881 gtgttttcat ccataattct tttatattca tgtttaggca tcaacaaggc tgctgcaaat
     2941 tcattggatt gatactcctt attggtattg ccacttctaa aatactgatt tccatcttga
     3001 ctattccata gttcatcatc aatgccataa cccatgtgta aaaataaatg tccaagttca
     3061 tgagcaatgg taaaattctt tctggtatct ggttgataag gagataccac tatttcaaat
     3121 gaatcatcaa cttttctaat aaatccatca gagtatccac ttaaagaact atcttctatt
     3181 accttgcctc ctaaagcatc aacaacttga tttatattta ctattggaat ttggattttg
     3241 tatgtttgga taatatcttg ggttatatca ttaattagct ctctgatttt gaaatccata
     3301 aaatcacatc cttatataat attttattta aataattatt tattataata ttcattatat
     3361 caaaaactat tttttttggt acatttaata ttaattattt tcattaacct tttgtattat
     3421 acaatataat tataccatat aaaaactgtt ttttgtcgaa tgtatgtttg aaaaaataaa
     3481 aattagtaaa ttatcttaaa aataattaga tatactttgg aagcaataag aatattaaca
     3541 ataagataaa tcgttgaaat accaacatgt gttaaataat aacaataaac aaataataaa
     3601 attttagatt tcagaatatg aaagaaccaa aaaacgatta actagtaatc ttaattaaat
     3661 tcatttagtt gatgttaaag tatgaaaact atagtagaag ttgtaataat aaaacgaacg
     3721 aaaattatca tactaaaaca taatacatgc tataattgta ttagataaat gcttgaatat
     3781 ataccaaaag tactcttttt ataagagtgc ttattttttt gaaattcatc aacatataaa
     3841 ctatcaagaa cattactcaa cacaccttaa aattgattta aattcttttt catacacaaa
     3901 gttatatgat ataataaaaa agtaaatatg taaccccaat acatctttac taagtcaaac
     3961 attattatat agagcattct tcattatgga gagtgctttt tcatttcttt gaataaccat
     4021 gttgattatt tataatattt tcatttaatt tatctttatc tatcaaattt aatgcacaat
     4081 taatacaaat gttagttttc atatgacttt tcttatgaaa agtaatatac ttattatcat
     4141 ctttatttat tcctttatta cagtaatcac ataatatagt cttagtcata tttttattcc
     4201 tttcatttta tattttccat aattaagttt aacatattta gtatatacct atgtatatat
     4261 atttaaaaca atgtttttta ttgcaatata gaatatattg tataaataaa aaaatggaga
     4321 atagatattt gataattgta aaattatgtt ataattaaaa tgcaagaata tatcttgcaa
     4381 gaggctacaa tctaagggcg aaagttttcg gaaatcacct tcgaacgaaa gggggtgagt
     4441 atatgaaaac acttatgttt atacttgtta tagcgtatta cattactatt gtaataaaat
     4501 ctattacaac aatagtaaag tctataacaa gattattaga ttctataagt agattaaaag
     4561 aatctttaca taaactaaga aatcgtcctg acggcaatca agacgatttc aatgaataaa
     4621 tcattactta aattattttg aatttgaaac ttcgctctag gctaatagat tgtagtttct
     4681 ttttttgttt ttgatacgaa tttacatctt tattatatcg cattttaaga aaaaataaaa
     4741 ctatgaatat tataaatcta ttttaattaa ttttttatca tatcattatt taaaagtaga
     4801 taaaactaaa aagggttctc tagaaatcaa tgtctatcta attatactta cttaccaata
     4861 ccatcacttg gtgtaaacaa gactctacta cattttctcc gtactctaat ataaaatcat
     4921 ctaactgtgt atctaaaaaa ttacaataat catacgaact gctaatataa gcagtcaaca
     4981 tgtgtgtaca tttatccatt ttatttttaa acatataaat tattatcccc ctaaaaaact
     5041 ttcataaaaa caaaaagaac aatatctttt tggcaactgg ctgacataac tcataagata
     5101 tttatataag tcttagtccc tatagctttg cgtcactaaa tttctctagt tttgccgatt
     5161 tagttttatt ctacaactaa aataatacaa tagaattagt tattattcaa caaaattgtt
     5221 tgaaaattta ataattttat agatatgaaa gttattttct tctaagaaaa cagactaaat
     5281 gcgtagaata tttggtaaaa cttacctgta tcaattgaaa tcagaaggtt ttattattga
     5341 tttagattag aacaatttga gggagtgaca taaaatgaaa caacaagaag tagttaataa
     5401 actacgcagg ggagaattga tgttgatgga atacttgtgg aggaaaaatt ctattttatc
     5461 taaaaaagaa ataatagaag caatgaaaaa aagatataag tggaggaaaa gtactacaga
     5521 aattctatta aaaagattag taaaaatgaa aacattaaaa aagaagagga taggttttca
     5581 gtttagttat gaagtgctag taactaaaaa agaatattta aatgcaataa aagaagatag
     5641 aaaggtaact aaatatgata gtttttttat acgaatgttt accactatgc ataaaaaaga
     5701 aaagatgaca gaagaacaaa taaaaaaata tatagaaaat atggaaaaaa ttggaaaagg
     5761 gtaatttata tatatattaa ttatttttaa aataaatttg ttataatatt taaatataca
     5821 taaacataca taaatttaca aaaagggggt gtggcttatg ggattcaaga aattgccaga
     5881 ttctgagtta aaagtaatga agtttatctg gggattagat ggaaataagg tagcatcagg
     5941 agaagttgtg gaagcaatga aacaaattta tgactggaat aaaaatacga cattaacaat
     6001 actgtctaag cttgcaaaga aaaactattt gtattctcaa aaaacaagca agtgtacata
     6061 ttatactatc gctgtaagag aaaaagatta tttaaaagtt gaaacaaaaa aattctttag
     6121 tttttttcat aataattctt taaaaagttt tttcactgct ttaaatgatg aagaaaattt
     6181 aagtgatgat aaattagata tgttggagga atgggtaaaa aattgggaag aagatgaata
     6241 aaatgaatgt gatactaaaa tgatactaat atgttttata gcgtgttaaa aaatatagaa
     6301 aatatagaaa taatagaaga aaattaatgt aatagataaa gttttatcag attaaaaaga
     6361 aaatcaatag aatgggaata aaatatagaa tgccaaaaat ccacataaat acaggatttg
     6421 aggtctctct tacttctatg ttatactggt ttgatactat caatatttgc cagtatctta
     6481 tggattaata agcaaaaaac atcctgctga atgataaatt cagcggggtg tttttatttt
     6541 gttttagaac tcctttgctc tgaaactcga agtatttaac actgatgatg ttgttatctt
     6601 ttagttcctt ttgtgtcatg ctctgaaaga caaattgata caataaaaaa gtaatttctt
     6661 aatcattgat ggagatatgt atttatgtta ctcttgatgg taatttgagt aatattgttc
     6721 atagcttttt atattcactt aattagaaaa ccatttggta taatcataaa taaacttgat
     6781 gatataatag aaaagattta taattattag aagtatataa aagtatttta tgtctatgaa
     6841 atgtatgtct ataaaacata tagatgactt ttgtatatta atgtatgaat attgatatta
     6901 tagaagaatt gagttgtcaa tgatactaaa tcaaatattt atagaagctg gagggattat
     6961 gagaaataaa ataattatag gaattacttt ttcacttgta ttactaatgt ctggatgtgc
     7021 ttcaaaacaa accgcagaaa taaacgtatt agcaactact gatttacatg gagttatacc
     7081 ttatgagtta acttcttatg taaaagaaga aagaaaaaaa gataaaaatc taactttagt
     7141 agatgcagga gatttttttg atagtggaga agtgtttggt tctagcatgg atagttattt
     7201 tagtgctaga tataaagatg gtgataataa cactgaaagt tatattgaga cgcctatttc
     7261 aaaagatatg aaagaggtag gttatgatgt tgcagttctt gggaatcatg aatttatatc
     7321 caacaataaa ttttatctag ataatatgat atctgatttt gagaagcaaa aaataaatat
     7381 tttatcggca aatacgtata aaaaaaatgg agatagttat acaaaaccat acataataaa
     7441 aaatattaat acacctgaag gaaacgtaaa actaggaatt ttagggctta ctataaaaga
     7501 agttggtgag aggaaacagt ggaaagatgg aaaacttgtt gactctaagt ctttagaact
     7561 aaaagaccaa gagggttaca atggtgaatt gtatatgaat gatttagtag aagatgctaa
     7621 aaagtgggtt ggtataatgg aaaaagagaa gcctgacatt atagttgctg tggcacatac
     7681 aggtgagaaa cctaagaaac ctaaaaaccc aggaaataga atacaagact tagctcaaca
     7741 agttgatgga attgatgcta tagttgcagg tcataatcat gttcaaattg agcaacatga
     7801 ttataaaaat aaatcaggag aaaatgttat agttactgag ccaggaaagc atggggaatg
     7861 tatttctaag attaatttta aattagaaaa aaacaatgat aaatggaata tagttgacaa
     7921 atctagtaaa ttaattaaat ttgaaaaaaa tcaagaaagt gataaatttg gagaatttat
     7981 ttcttcaatt aataaagtaa gtaaagataa gaaagaaata agattatcag aagtaaagac
     8041 tcctgaatgg gataaaatat atgtttttaa atctggaaca tctgcagatg atatatataa
     8101 aacaatagga tataaatgga gaaatatatc atctccaaag ggtgatgaca tggtgcagat
     8161 tgttgtaatg aataataata agcctgttag ctatgtatat ggtgaagctg aagttatgcc
     8221 aattaatata aaatgtgatg aatcagagta taaagataat gttgtaacta tttatcctaa
     8281 taaaaatgat aaatttaaaa ttgaaaaagg taaacaagaa tatagtatta atttaaaaca
     8341 tatacaatag aaacttttat cttatttaag tttagattgt acttaaaata aagtgtgtat
     8401 tattttaaaa attgatgata attaaaatca caacattaag gaatagtaca cactttttat
     8461 gctaaaaaat agaatgttaa aaaattaaac ctttaaatta aagtacattg cttatattat
     8521 ccaatattat tttcaaaggt tgtgtaatat ttttatcctt atgtaatatt gctaacattt
     8581 tattttccat atctatccca tctaattcaa tcaatcgcaa ttttttatgt aagagtgaat
     8641 ctaataataa attttctggc aaaatggtta tacctaaccc tgcttgtgca gctttaataa
     8701 gtgcaaaaga attaacactt tcccaaacag gataagcttt ttggtttgaa agagataata
     8761 cactgtccaa agtattgcga atggcacttc cttgctcacg taacaataac ggaaacgtgc
     8821 ataactgtcg tagagataag gcttgtttag tattggtggt ggttatgcaa tcatactttt
     8881 aatccaagag aaagtagtaa atcaaactgg atggataagt gagaaaatgt ttacagatat
     8941 tataactatt tcacaaatga caccagggcc actggctgtt aatacttcta cttttgttgg
     9001 acttcaaatt ggagggtttt ggggagcagt tgcagccact ttaggttgtg tattatgtgg
     9061 tgtagtaata tctctatttt tatataattt ttttcaaaag catcagaact ctacttatat
     9121 atttgaaata ttaaatggtc taaaatcagc ttcattaggt ttaattatct cagctgcggc
     9181 tacaattata atccttgcat tatttgggac gaataaagtg tacttcaatt ctatatttga
     9241 gatgctaaac tggactgcac taataatctt ttttgttaca ctactgatag tacgtaagtg
     9301 gaaaattaat cctattgtga ttataataat aagtggtata ctgggaatat ttttttattt
     9361 ataagttttt ggtaagtaga ggatatctat ttttttatat cttaaatcca aatagctaat
     9421 aaagtaaggc tatttggatt tttaataaat tctgaaaaga taatcagaaa cccatataac
     9481 atttaaatta tatcactggt tttctacaaa ccaatcataa gcttcttggc aaaatttctc
     9541 actatctata tagtaactat tatgaacatt attaatttca acaagtttct ttttacattt
     9601 tagtgaatta taatagctat caaaatattg ggttttaaaa tatctatcat gaagtgtttt
     9661 aaagacaaga gtaggtatgt tgactccatc ttttatctta ctatcttttg caataaagca
     9721 ctctaacatt gtattaatta tctttgtact atttttccag atatgaggat ttttcttttc
     9781 aaatatttta taaaattcat tatcatagac ttcattataa cctttatatt taggtggttt
     9841 tactgttatg tgaaaattag gaagaaactt aaagaaaaag tttaataatt taacagtgag
     9901 ataggtatag cctactcctg ttgtgttttt ataatcaaca caagcaaact gagcaaaact
     9961 ttttaactta ttgtctgaac atgcataata ttgtgcaaac ataccaccaa ttcccgtatt
    10021 cccatataga tgtatgttgg aagaataatt tttttctatg tatgtaatga cagaatctaa
    10081 gtcttttaca attgaattgc gagaaaaatc tttttcatat ccatcacttt tccctgttcc
    10141 tgaaaaatca aaagcaaata tatttacatt atgtttggca agtggttcat atgctttttg
    10201 catctcaagc gtagtgacaa taggagtatg tgtaacaaca atattcatgg atgattttct
    10261 ggtaataaat gagttacaaa aaatcattgt atctccattt ggtattttta tatgtttcca
    10321 actcatttga ttttcctttc tctattataa aatataataa tttttatgtt ctgttttata
    10381 tattattcat attttatcac agataatata ctaaagttaa tttttttatt gtacacctat
    10441 tataataatt cttctataat ataagacatt ctataatttt atatttaagt tcatgtgtat
    10501 ttaattgttt ttatataaaa tgtccagtaa tactatttgg atttattttt atttcatcag
    10561 gagttccaga agcaacaatt tcccctccat ttattccact gtctggacct atatcgataa
    10621 tccaatcaga agcacgtata acctctgtat tgtgttcaat aattaaaagt gaatgctgtt
    10681 catttacaag ttttctaaaa gtaattaaca aattttctat atctttaaaa tgaagtccag
    10741 tagtaggctc atccaatatg tacagcattc gttttttagt ttttgtccct aattcttttg
    10801 ctaattttat cctttgagat tctcctccac ttaatcctaa tgtattttgt ccaagcttta
    10861 gatatccaag tcccacttca tctaataagg agagttttct atatatatta gagcaatcgc
    10921 taaaaaatgt ttttgcttct gttacttcca tgtcaagtat atctgcaatt gtctttccct
    10981 tgtattgtat agacagtatt tctttttgat atctcttacc ttgacattca ctacaagtta
    11041 cccattggtc tgccatatat tgcagaataa tttttgtttt acctaatcct tgacagtttg
    11101 ggcattgccc ctttttgcta ttaaagctaa aatagctttc atccaataat ttttgttttg
    11161 cttgtggagt ttcagcaaat agagaacgaa tttcatcaaa aatattgata tatgtagaag
    11221 gtgtagaacg gctagatttt ccaataggtg tttggtccat taagataaaa tcatcaatag
    11281 catcaaatcc agtaaattca gtataatttt tatctgggct agatttttgt ttcaattttt
    11341 cttctagagc aggaagtaaa ctgtgaaata caagagagct cttaccagaa ccactaacac
    11401 ctgtaataga gcacatacag tttaagggaa tttctacatc aatatttttt aagttatttg
    11461 catggcatcc ttttaagctt aaccatttac ttggtatagt tttattttgt gaacctgttt
    11521 tattgtatgt acttaaatat ttacctgtta tagagtttgg attttttata atttcttggg
    11581 ttgtaccttc tgcaataatg aacccccctt ttgtaccagc atttggacct acatcaataa
    11641 tataatcagc agacagtatt gtatctttat cgtgttccac aactataaca gtattaccct
    11701 tatctcttag ctcttctatc attttgatga ttaaattatg gtctcttggg tgtaaaccaa
    11761 tagatggttc atctaaaatg taggttaagc ctactaattc acttcctagc tgacttgata
    11821 atcgtactct ctgcagttct cctccagata aagttggagc tgttctatct gttgatatat
    11881 agctaagacc tacctttaat agataactaa ctcgaatttt taattctgtt aagatatcat
    11941 ttaccaaaga gagctcattt ttttgaagtt gatttggtaa ttcacacaac caattccata
    12001 actgttctat cgtcattttt gttagttcag ggaagcgata acctttgatt gtagtgaatc
    12061 tagcctcaat gcacagcaat tcgccaccac atgtattgca aggaattttg ttcatatatt
    12121 gatgcaaggt attattttca gaactagatt ctctaaaaag tctctgaatg tggttgattg
    12181 ctcctgaagc aggtcttcta atctttgatt ctcgtccctt tgattcaaag ctaaattcat
    12241 atatcttatc gtctgtacca tataagattg catctataaa ttctcttggt aattcattcc
    12301 aaggtatatc taggtctata tttttatctt ttgctattgc atataattca cctaacatcc
    12361 aattaccatt tggctttttc ctcctcaatt ttccaaaata gtaagtagct ccatctaata
    12421 ttgaaacagt tgggtctttt acaattaatt gaggattaac ttgataggta aaacctaatc
    12481 cattacaatc gtgacaagct ccagtatggg agttagcatt gaaggttgaa gtatttatct
    12541 tagaaaaaat agtttgacaa tgtggacaat aattttttgt attattcttt ttttctaatg
    12601 gaattttgca atatggacag taactttttc cgattgatac aaataacatt cttaaataat
    12661 cccaaatgct tgtaagagta ccaacagtag agcgaggatt ttggcttcct tttttctgtt
    12721 cgatagctat agtaggggtt aatccctgaa gtaaatcaaa ttccggtttt tgaagctgtt
    12781 ctgaaagttt tgctccatta cctagatttt caaaataacg tctttttcct tcttcataaa
    12841 tcgtatcgaa agctaaagaa gattttccac taccacttac acctgtaata acagttattt
    12901 gattttttgg aattgtaacc tcaacatcct ttaaattgtt ttgccttcct ccttttaaat
    12961 agatagagct tttattatga caaagtgaat ttttaattga tttatttatt gattttgtaa
    13021 atttgaattt cttttctagt tcaagaggat tgcctaattc ttttatttcc gaaataccta
    13081 atatttttaa ctgagaaaag attgatttca aataatcttc aggcaatttt tctattaaca
    13141 aattaaggtc ttctattttt atatttccgc ttgataatat ttctgccatt tcatctaata
    13201 aatttttttc tgctcttgtt aattgattgt attttttgga acttaattct gtccataaat
    13261 cccatggaag caattctaaa ccaatcatat tattaaagtc atgtagaaga ttacccttta
    13321 cagaatgcca acctttccaa tttttattat atccaaagtc atctggatga gcatgtcctt
    13381 gccaacatct tatccaggct tctgaaccag ttaaaaaacc atctgttttt ccgacatcat
    13441 gagtgtcaaa attaatttga aaataatttt tttgtatatc atctatttgt gcatctattc
    13501 ttatccatct ctttgttaga gtatcatagt attctacaag ccagtggtct tcataagtaa
    13561 gttcactttc aaaataatta gcaaaacctg ctctcattct agcctcaaaa cctcgatatc
    13621 ttaggagcga tacaagaagt aaagaataat ctctgcacat tccaacaagc ctttgttttg
    13681 ggtttcttgg aatagttagt gggttagaat ttatttcaaa tattcttttt aacatttgag
    13741 gaattgtacg aagcaattcc tcatcagatt gttgtttatt aaaggatata ccatataatt
    13801 ttccttggtc tccatgaatt actaggcttt gaaccacttt taataattca attggagtct
    13861 ttggtaaatc ttgatattta ttttcaaatt ttttaggatt tgtgatgatg ctttgatttt
    13921 tatagttatt tattttcatt tatatttcac ctctctaaat ggatgatata ccctgacatg
    13981 gtgtcatatg caaggacaat ttagattttt tggccaaaat ttaaaaataa ataaaaaatg
    14041 atacagtgat aaattgtaat acaaatatag tttcaaattg catataatat aattatttaa
    14101 taaaaccatt atctatggaa tgttaatgaa atgttaagat agcattcttg aatattaaga
    14161 aatagaatac tataatatag tgtgaaggat tcttagtaaa aaaatttgta agtgttaata
    14221 tacattaaaa aataggttta taatttggag gaaaaaaatg aaattatcaa ggtataagaa
    14281 aaatagttta gttctgtcta taattttatg ttcacttatt atttcaatcc ttgtaattac
    14341 tgtttttaat accgtaaaac tacacaatat atctaataaa caatctaaaa actatttaaa
    14401 cgatgtatct acacagattg taatgaatgt tgattctaaa atcaaattta ttttatccga
    14461 cttaagaata atggcagatt ttattaagca atatgaaggt gatagtcgat atgagtattt
    14521 atctaaaaga aagactagtt ataagtatta tgatgttgga ataatagatt tagaaggtaa
    14581 agctgagttt ttaagtggaa aaaagtttga cttaaagaat actgcttcct ataaaaaagg
    14641 aattgaaggt aaagaatact cagaagtaat agagtcaatg ggttttgttc tttatagtgt
    14701 acctatattt aatgataatc atgaagtatc tagtatttta ataggtgtat ccaataaaga
    14761 aagtatgaat gagattctta atatagataa ctttaatgga gaaggaacta ttgaaattat
    14821 taatagtaag ggaaaacctc ttttcatagg aaaaaatact gagttaataa aagaccttag
    14881 ccataaatat aaggattctg cagatgaacc ttgggcacaa aagatgctta atgattttaa
    14941 aaatgataaa tcagggaata ttacaataac ctcatcaaaa ggagtacaat gcttattaac
    15001 ttatcatcca attacaatag gtttaaatga ttggcacttt cttctcatag tacctgaaga
    15061 tgctgtactt ggtgaactta ataagttaaa ttcttttaca ataacaatga catttataat
    15121 tacatgtatt attggaatta taacattaat tttatatatt ataagaagaa aatatgtaaa
    15181 tcaaatagaa aatattgcat atttagatag tataacaaat ggcataaatt caactaagtt
    15241 tagtatgcta gtcaaacctt taatttcaga atcacctgat agtacttata tgatgatagc
    15301 aatgaatata aaagatttta agctaataaa tgattgtttc ggtagtgaaa agggaaatat
    15361 gacactaaaa catctttaca atattttgta taaaaacatt gatgaaaatg aagaatttgt
    15421 gtgccgtcat gatgcagacc ttttctattt gcttattaag aatagaccag tgttagaagc
    15481 cctggagtta ttatataaaa tagaagctga cacaaattat tttaataaaa atagggaaaa
    15541 tccatacttt ttaagactat cagtaggtat ttacacaatt gaaaatcata atgaagattt
    15601 aattacaata caagaccatg caaatacagc aagaaaaagc tttaataaaa ctcatcaaag
    15661 tgatttttct ttttatagtg atatagaaag aaaacgatta atatctgaaa aggaaatttc
    15721 aaatttaatg gaaaaagccc ttgaaaataa agaatttttt atgtgcttac aacctaaaat
    15781 tgatataaaa agtggaaaaa ttagtggagc agagtctctt gtgcgttgga aaaattcaga
    15841 aaagggcata atttatccaa gtgattttat tcctcttttc gaaaaaagtg gatttatatg
    15901 taagttagat ttatatatac tagaagaaac atgcaaattg atttctaagt ggataaaaga
    15961 aggtaaagaa gtgttgagaa tttctgttaa tgtatcacgt caacatttga atgataaatt
    16021 gtttttagaa aaatataagc atatatgcaa taaatacaat gtaccaacat gtctgataga
    16081 tttagaactt accgaatcta ttttcttaga aaatccagaa gctatagata taatagagga
    16141 tattcattct aatggattta aatgttctat agacgatttt ggatttgggt actcatcatt
    16201 agggatatta aaggatttta aagttgatat aattaagtta gaccgttcat tctttgttag
    16261 caaaaataat atagaccgtg gtaaggtagt tattaagtct attattgaac ttagcaaaag
    16321 gctaggtatg aaagtaacag ctgaaggaat tgaagaatta gaacaagttg agttcctaaa
    16381 aaatgtggga tgtgattata ttcaaggtta tgttttttca aaaccattat taatttctga
    16441 ctttgaaaat tttgcatatg aaaataataa aattaaaaat atccattatt aaatgtacaa
    16501 gataaaaaat ttaggcaagt tatataatta aaaatataac ttgccttttt tatttatata
    16561 tttaataaaa atatatttgc agattttgta aaaataattt tcaaatattg taagttgtgg
    16621 ctaaagcttt attgtattat tctgaatata gaaagatagt tactgtctta gataaaaact
    16681 gaaacataca taataatata aaatttgcta tattaataac tctaattatt ttggaaggag
    16741 ggaaaatatg ataagtggga gaatgttact catcatgaat tttctaaaag gaaaaaataa
    16801 gacaagttac aaggatatta gcaaacaact tagtatagaa gaaagaaaag ttagatatga
    16861 tataaataat ttaaatattg ttttgcgttc attaaacaag tcagtaatac aaaagatgaa
    16921 caaaggtgtg ttaattattc ctgatgactt ccaagtagta tgtataaata ataacgaata
    16981 tgtattttcc ttaactgagc gagtatctat tatgaaaatt atatcaatgt ttaaaataga
    17041 taatctaaac ttagaaaaat taagtaaaga atttcaggtt tctagaagtt caattaaaaa
    17101 tgaccttaat gttttgtcaa gtgaattaga aagaaaccaa ataactatta cttatgataa
    17161 atcttttaaa ataagtggag aagaagacat tatatataag caaagattga acatattaaa
    17221 atcgtattct tatctttttg gtaaggaaaa atctgattta agtgtatttg agaagtattt
    17281 agtgaatgta attgaaaaaa tattcaaagg gatttatttg attgatatat ataattggtc
    17341 tatgaattta ttattgcaaa tgggatggac tttaaatgat gaatctttta catggtatgt
    17401 gtcaaacatt ttccttttta catggtatat acattcagat gaaaaacatc ctttagaatc
    17461 tgcttcatta agtgagccgt gttttgaaaa taagtttgac caagaatttg aaacaattat
    17521 tcaaaaaaag ttgactaagg aacaaatttt tctgttaaag agttttgtat tttttacaaa
    17581 taaatatgca agtttaaacg aggatatgga tttgattagt acagaaatta tagttcagga
    17641 cttaatttac aatatgtcag aaatattaga gattagcttt aaagaagata tgattcttta
    17701 taaaggatta ctcaatcata ttgccccatt gatagagaga atcaagcaga atatacagat
    17761 ttatgaggaa ttacttcatg taataccaga taaatatcaa tatgtacttg aagctactaa
    17821 ggtttctatt caaaaaaaca gagttttaag tcaaataaag aatgaaaatg aaacaatact
    17881 tttggcaata catttcttag gaagtataca tagaaatgag aggaataact acaaaaatat
    17941 attgttagtt tgtggatttg gatatggtgt aattgctatg ttaaaggata gtttagtaaa
    18001 tgattaccag ataaatatag tagagagtat tccatcatat aagttacaag attataaaga
    18061 atgggaaagt attgacttca ttataacaac atcaaagata gtaatagact tgcctaaaac
    18121 aattattgag ataaatccat ttttacaaga agaggattat ttgaagtttg aagaaaaagg
    18181 gataaaaaga aagaacgtct taactaatta tatgtcaata aaaaaaaggt tggacttttt
    18241 agaagaagat gcccaaaaaa gagtattaag tattatatgt caagaacttg gatacagtga
    18301 tgagagaata ttatttagac aacttaattt aagtgattta atagggattg ataccataag
    18361 gataattgat ggagatatga aatgggaaga tgctgtaaaa tttagttcaa acatacttgc
    18421 taattgtgat tttgtatcag cacaatatgc tgagaatatt atagatattt taaaaaatgt
    18481 gggtttttat gctgtaaaag ataacgaatt tgctttacta catggcaatg atagttcatt
    18541 agtcaaagta agttcgataa gtttattaat atgtaaagaa gcagttagtt ttggagataa
    18601 aaaggttaaa atcatatttt gcctagcaag cagagataaa aaagagcaaa ttcctgcaat
    18661 aattaatcta actaaaatgg tttataagac taattttatt gctatgttag aaagtgcaaa
    18721 gacaaaagaa gaagcagaag ttttaattca taaatatgag aaggaggtca ctgtatgaat
    18781 aaattagtta atgtaaaatg ttcatttaaa atacatgtta attcaaaaga agaagccatt
    18841 atatcgttag ttgatgtagt gtcaaaagaa ggatatttaa tagataaaaa tcaattttta
    18901 aaagatgttt taaagagaga agaaacattg tcgacttata ttggacatgg tataggtctt
    18961 cctcatagtc aaagtgtagg tgttaaaaac tcttgtatta caataggaaa gcttgatact
    19021 cctattgaat ggacagaaga aggagaaaaa gtggatttaa tatttttgat atcagtaaca
    19081 aaagacaatg aaaataatct tcatttaaag attttatcaa aattagcacg tttattgatg
    19141 catgaaagtt ttagaaatca aattagatgt tcagatgaac aaactgttta taatcttata
    19201 aaagaaaaaa tagaggagga agattaaaat gagaatttta aagtttttgc aaaaacatct
    19261 tatgacagca acatcttata tgattccatt tgtggttgca ggaggaatat tatttgcttt
    19321 atcagtaact ttaagtggac aagctgctgt tcctgaaaca ggctggttgg ctaaactgaa
    19381 tcaaattgga gctgctggct tggctttatt cattcctata ttaggtggat atatagcatt
    19441 tagtatggca gataaaccag gattagctcc aggtatgata ggtgcatatt tagcaaaaga
    19501 agtaaatgca ggttttatag gtggtatcat agcaggattt atagcaggat ttgttgtttt
    19561 acaattaaag aaaattaaat tagctcctac aatgagaact ttaggttcta tatttattta
    19621 tcctttagtt ggtacattga ttacaggtgg tataattgta tttttaattg gagaacctat
    19681 agcttctttt atgacatgga tgacaaactg gttaaatgga atgtctggtg tttctaaaat
    19741 tcctttaggt ggaatcttag gaggaatgat agcctcagat atgggtggcc ctataaataa
    19801 ggttgctgct acttttgccc aaactcaagt tgacacactt ccatatttaa tgggtggagt
    19861 tggcgttgca atttgtatac ctccaattgg tttaggatta gctacattat tgtttccaaa
    19921 aaaatttagc aaggaagaaa gagattcagg taaagcttca ctattaatgg gatgtgttgg
    19981 aattacagaa ggagctattc catttgcaac atcagatcca gttagagtaa taccttgtat
    20041 tatggctggg tcgattgtag gaaatattat ggctttttta ttaggatgtt taaatcatgc
    20101 accctgggga ggtctgatag tgttacctgt agttgacaat aggttggggt atattgcatc
    20161 agtattaact ggagcagtag ttgttgcggt attaatgaaa ttagtaaaaa aagacgtgaa
    20221 agaagatgaa gaaattgaag aagatttaga tgaatcaatt gaattaatat ttgaagaatt
    20281 ataaatataa atggaaggaa tttgtataaa aaagtaaata taaaactata aatttaaagg
    20341 agataagaat atgaaaattg tagcagtaac atcttgtcct agtggagtag cacatactta
    20401 catgtcggct gaatcacttg aattatcagc caaaaaattt ggtatagaaa taaaggttga
    20461 gactcaagga agctctggaa tagataatga attgtcactt aaagatattg atgaagcaac
    20521 ttgtgtaata ttgactaatg atgttgagat tagaaatatg gaacgtttta aaggaaagaa
    20581 ggtagtaaga atgagtgtat ctgagataat taagaaatct gatgcattaa ttaagaaaat
    20641 aaaagatact tttcaataaa aattgattta ttttacatat aactcaaaga tgtttttaaa
    20701 gaaattttta ttaaaagcat ctttgaaaat atcttaaaaa tagaataaaa ggagatatag
    20761 tcatgaaaaa gttaccaata aagactgtcg tgcaaagatt actaaactta caagaagagg
    20821 ggaaaagtgc aactctttta ggaattggtc ctatgtcacc aaacttgtta caagcaagtt
    20881 ttgaactagc aaaagatgat gattttcctt taatgtttat cgcaagtaga aatcaagtag
    20941 atgcagatga actaggtggc ggttatgtaa atggttggaa tcaggaaact tttacaaaag
    21001 atattaagaa ggttgccgac aaagttggat ttgatggttt atattattta tgtagagacc
    21061 atggtgggcc atggcaaaga gataaagaga gaaatgacca tttgcctgtt gatgaagcaa
    21121 tggagttagg aaaaaaatct tatttagcgg acattgaagc aggttttgac ctattgatga
    21181 ttgaccctac aaaagaccca tttgaaattg gaaaagtaat tccactagat gtagtactag
    21241 aaagaactgt agaattaatt gagtattgtg aaaacgagag aaaaagactt aatctaccag
    21301 acataggtta tgaggttggt acagaggaaa ccaatggagg tctgacttca actgagacgt
    21361 atgaaacatt tataactaga ctaaaggttg aactcgataa tagaggtttg ccaatgccaa
    21421 catttatagt tggtcaaact ggtactttaa ctagaaagac agaacaagta ggaactttta
    21481 attttagaaa tgcttatgat ttagctcaaa tggctaagaa atatggagtt ggtttaaaag
    21541 agcataatgg cgattactta gatgatgtaa ctttattaga acatatacca tctcaaatta
    21601 ttgctacaaa tgtagctcct caatatggta ctgaagaaac tagggcatat ttaaaattag
    21661 cagaagttga gtgtaaatta gaaaaagagg gtttagttga gaaaacttct aatatcagac
    21721 atgttcttct tgttaatgca attgaatgtg gacgttggag aaaatgggta gtaggagaac
    21781 aaaaaaatct aactactgaa gagatattta aggatgaagt tttatctaat gaaatactag
    21841 atattgcagg acattataca tttaataatg atgatgttaa aaaagaaata gaagtgcttt
    21901 atgataattt aagtaagaat aatattgatg gtcaaagatt tgttgtagac catattaaac
    21961 gtcctttgcg tgattatgca gaatgctata acttaaaagg tgttactacg aggattttaa
    22021 ataaataata ggacttatag tggtgagtat tgttatacta ggtatttata gttataatta
    22081 tacttaccac tattaaattt aggaggacta atattttgat taatttaatt tttgatgtag
    22141 atgatacttt atataatcaa ttaacgcctt tttacactgc atataataaa gtgttttctt
    22201 caataaagga tatttctatt gaagatttat atatgagtag tagaaagtat agtgatgagg
    22261 tatttcatat gactgaaaat ggagaaatgc caatcaaaga aatgcatatt tataggataa
    22321 tgaaagcttt tgaggagttg ggaaattcta ttacagaaaa agatgcacaa agttttcaag
    22381 atgagtatat atatcaacaa tcacaaatta cactaatacc agaagttgag aggattttaa
    22441 atttttctaa agaaagaaat attaatctag gaattataac taatggccca tcaaaccatc
    22501 aaagaatgaa gttaaagcag ttaaatattg aaaactgggt tgataaaagt aatattttta
    22561 tttctagtga ggttggattt tctaagccag atactaatat ttttagagta gctgagaatg
    22621 ttatgaattt agatagagaa aatacatatt atgtgggtga ttcttataga aatgatgtat
    22681 taggtgctaa aaaagctggt tggaagagta tatggttgaa ccatagagga catgaggtag
    22741 aagagttgtt ttataaacct gattttgtaa ttttggaaca taaggatttg atatctttat
    22801 ttataaaaat atgtagttat aaaaatatgt agtaaaaaaa tgttaataat agaattgtat
    22861 aaaataatta ataataacta tataaaatta tatgtttaga ttgtgagcaa tctattttat
    22921 gttaaaaata gattatttag aagaagggga aatcttaaaa aaatttgaat atcccctttt
    22981 tattatttaa ttaaaatgaa atagttagaa atatatttta tttagtttag tcaataacat
    23041 tttgggattc tttataacta catgttaact gttgaatagg tttatcatat ggtttaaccc
    23101 atcctttatt aatacttaat tctgtaagtg ctgtgtgacc ttctaccatt tgagttaatg
    23161 aagctgaata tatagctctt aattcaggtg tactacttgt caatgcagaa ttaagataca
    23221 tattggcaga tgctttagca gatgaaagca tacttaacat tattacttta tcgtctatat
    23281 aagtattgtt cttaattaga ttttctatca tatttctcat gttatctata cctcctcaga
    23341 aattagtatt tcattttcaa ctataaattg ttgtatagct ttaattcttc cttctgttgc
    23401 taatatacta gattctgatt gtctttttag gtcttcatct gatattaaca tatttattgc
    23461 tctttgcata agtaatccgt cagactccat ttttataatt gctgctaaag atattttttc
    23521 agtttctgaa agtattctca tttaatcatc tcctatattg taatttatgc tttaatagta
    23581 tgtctttctt ttcaaggaaa taaccattac acttttttac agtattttat attctcttta
    23641 tatcaaaatt tagtcgacct aattaatata attttgtagg atatttatca ttaaatatct
    23701 ataaaataaa ttatttgaat attcataaag caaaatttat ttgtatgtac ttcttcaaga
    23761 gtcaatatga gttttttcaa aaaattaatt tttatgataa tcattaaggg ctatattttt
    23821 cttaaagttg tgattatcat tattaattta ccttagaggt taattaggtg tttaatcaaa
    23881 gttaatgcct ttagaataca aatgtattct aaaggcattt ttactatgta ttttcattta
    23941 tattactaaa cattatctat ttttatatac atttctatgt attttatttt catcaaatcg
    24001 gtctataaac tcattttttt cttcactata tccaatagat ataagtgcat aaggaactaa
    24061 ttttaatggt aagtctaaag tttgtctaac tttatttacc actttatttt taggaaatac
    24121 tcctgcccaa caagcagcta gaccttgatt agtaacttct aataataaat tttgtgtgca
    24181 agcacctaaa tcttgtatcc atttaccagg ttttaagaat ttatctctat ttccaagcac
    24241 tactatacat aatggtgcaa attctatatg ctttgctcta tgctgtgact ttgagagctg
    24301 tttcagcagt tccttatcat ctactataat aaattcccaa ggttgagcat tttttgatga
    24361 aggtgcttgc atagctgatt ttagtatttc agttatttta tcttcttcta tatttttatc
    24421 tatatatgtt cttattgaac gtctattttt tataacttct aacatacaga ttctccttta
    24481 aataaaatta tttctattta tataatatca ttactttaaa ttttagctat tacttatata
    24541 aagaataaac tttgtgttgg ttttatctaa gtaaaagtaa cattcagaac taaaaaacaa
    24601 gactataaat ccaaagtatt aattaaaaaa gaagtaataa aaaataatat acaagattta
    24661 aaaaagagta ttgggcttaa aatttaatta gaaaaccaat tttgagataa tctgtttttt
    24721 attttaacaa aaaaacataa ataaagttcg atacgtagcg aatgaaaaaa ttacaagaaa
    24781 tatttttttt aaaaaatttc aaaaaagagt tgataatata tgtatattaa tataaaattt
    24841 aaggtgtata attcgtataa taatacgaat gatttgtagt gtaaaataac ttataaacgg
    24901 agaggggaag tctaatgaaa gtagcagtag ttatgggttc aaaatcagat tatccaaaat
    24961 tagaagaagg gataaaactg cttgaaaaat atggaataga agttgtagca agagcattat
    25021 cagctcatag aacaccagaa caactttcaa tattcctaaa agaaatagaa gatgatactg
    25081 atgtaataat agcagcagca ggaaaagcag cacacttacc aggtgtaata gcttcacaaa
    25141 cattaattcc tgtaatagga ttacctatta aatcatcaac tatggatgga ctagactcac
    25201 ttttatcaat agttcaaatg ccaaaaggaa tcccagttgc aacagttaca atagacttag
    25261 gtttaaacgc agctttattg gcattacaaa taatgacttt aaaataccca aaattaaaag
    25321 aggatttgaa atcatataga gaagagatgg cacaaaaggt gttagaagac gacaagaatt
    25381 taagggggta gcagaaatgt tattatatga aggaaaagca aaacaagtat attctacaga
    25441 taatgaaaat gaatatgttg tttattataa agatgatgca acagcattta atggagaaaa
    25501 aaaagcagaa atatcttcaa aaggtatact aaataataag atatcaacaa taatctttga
    25561 aatgttaaaa gaaaataata taaatactca ctttataaaa agtttatcag atagagaaat
    25621 gttagttaaa aaagtagaga ttttaccatt agaagtaata gtaagaaata ttgctgctgg
    25681 ttctatctgt aaaagagttg gtcttgaaga aggtgtagtt ttcgatgagc caatttttga
    25741 aataagctac aaaaatgatg cttatgggga cccaatgcta aatgatgatt atgcagtggc
    25801 aatgaagtta gcaactagag aagagttaaa attcttaaga gaagaaactt taaaaataaa
    25861 tgagttacta aaagcatttt tcttaaaatt aaacctaaag ttagttgact ttaaaataga
    25921 atttggtaag gattctgaag gaaatataat attggcagat gaagtatcac cagacacttg
    25981 tagactttgg gatgtaaata caaatgaaaa gttagataag gacagattta gaaaagacct
    26041 tggagacctt gtagaaggtt atacagaagt actttcaaga atgaataata aataggaggc
    26101 aaatgtatgt gtggagtttt agggatttac tctaataaag atgtaactaa agaactatat
    26161 tattctttat attctatgca acacaggggg caagaaagct gtggtttagc tcttttagat
    26221 gatggagaaa ttaagtacaa aaaagatatg ggattagttg gagatgtttt taaggaaaat
    26281 gaattatcta agttaaaagg aaatataggg attggacatg ttagatattc aacagctgga
    26341 ggaagtcatg tttctaattg tcaaccttta gttggaagtt gtagaaaaag acaattagcc
    26401 atagctcata atggaaatct agttaatgca aattatttaa aagatatgct agaagaagat
    26461 ggatatatgt tccaaactaa ttcagataca gaagtgattt tatatatact tgctagatat
    26521 tacaaagggg atatagtaga aagtttaaaa gtgacaatgg attatataaa aggtgcatat
    26581 gctcttgtaa taatgagtca agaagaattg gttgcagtta gagacccaca tggattcaga
    26641 cctcttgtac ttggtaaaaa gggtgatgaa tatatatttg catcagaaaa ttgtgcaata
    26701 gatatacttg gcggagaagt tataagagat gtagagccag gagagataat agtagtcaaa
    26761 gatggagaac taaaatcata tttttattca gaaaattata aaccagttaa gaaaagttgt
    26821 atatttgaac acatatactt tgcaagaaat gatgcaacta tagacaatgt aaatgcatat
    26881 gaatttagaa ttaaatgtgg tgagagatta gctcagaatg aaactgtaaa ggcagatatg
    26941 gtagttccag ttccagattc aggttggcca ggagctattg gttatgcaaa tgctagtgga
    27001 ttaaaaataa gtgaaggctt agttaaaaat agatatgtag gaagaacatt tataaaacct
    27061 acacaagaag aaagagaaat agcagtaaaa ataaaattaa atcctctttc aacaataata
    27121 aaaggaaaat ctataatttt agtagacgac tcaattgtaa gaggaactac atctaaacaa
    27181 ttagtaaaat ctttaagaga agcaggagca aaagaaattc atcttagaat aacttctcct
    27241 ccagtagctt actcttgtta ctatggaata gatactccaa atcgctctaa attaattgca
    27301 tcaagtaaca acgtagaaga aatgagagaa tatattggat gtgatagttt aaaattccta
    27361 gatatagaag gaatgttaga tgcaacagaa cataagtcta ctttctgtaa agcttgtttt
    27421 gatggagaat acccagttaa gaaaattgat aaggaggaac tactttcatg ttaacatata
    27481 aagaatcagg tgtagatata gatgaaggaa atagagcagt agaccttata aaaggtaaaa
    27541 taaaaggaac ttatgatgga aatgtagttg gagatttagg taacttcagt ggattataca
    27601 gtttaaaaga ttttgtaggt atgaaagaac cagttttgct tgcatctaca gatggtgttg
    27661 ggactaagtt aaaaatagct cagatgatgg acaagcatga tactgttgga atagatttag
    27721 ttgcaatgtg cgtgaatgat ttaatttgtc aaggagcaaa accattattc ttccttgact
    27781 atatagctct tgggaaatta gtgcctgagc atatagaaaa aatagttggt ggaattgcag
    27841 atggttgcaa aatgtctggt tgtgcactaa ttggtggaga aactgctgaa atgcctggaa
    27901 tgtatggaga agatgactat gatttagcag gattttctgt gggaatagca gacaaagaaa
    27961 agattgtttc tggaaacaat gttaaatcag gagatgtatt ggttggtata tcttcaagtg
    28021 gagtacacag caatggattt tcttttataa gaaagatatt tttagaaact tacaattata
    28081 aaatggaaca atatgttgaa gaactaggaa tgacagttgg agaagcactt ttaacaccaa
    28141 ctaaaatata tgttaaatta gctttagatg tattagctaa acatgacata aaagctatag
    28201 ctcacataac tggtggaggg cttatagaaa atataacaag agttatacct aaagggttag
    28261 gactagatat caataaaaaa tcttgggaga agcctcctat atttaaaatg atagaaggtt
    28321 ttaatgctgt tgatgagaga gaacttcata agagttttaa catgggtatt gggctagttt
    28381 taatagtaga taaagaaaat gctgatgatg ttgtaaactt tataaataat agagaaaatg
    28441 acaatgctga ttatgtagat aaaaaatata gtgaattatt agaagataaa gcttatataa
    28501 ttggtgaagt agtagatagt catgaaggtg tagaattatg ctaaatatag gagttttaat
    28561 atctggtggg ggaacaaatt tacaagcagt tatagatggt actgagtctg gagaaataaa
    28621 aggtcaggtt aaagtagtta tctcaagtaa gcaaggtgct tatgggctag agagagctaa
    28681 aaatcataac ataaaagcaa tttgtgaaac tgatgaagac aagataatag aaattcttaa
    28741 ggaaaataaa atagatttag tagttttggc tggttattta aaaataatca gcccaaagct
    28801 ggttaatgag tttagaaaca aaatgataaa catacatcca tcattaattc cttcattttg
    28861 tggagctgga ttctatggag aaaaagttca tcaaggtgtt atagattacg gagctaaagt
    28921 aactggtgct acagttcatt ttgttgatga aggtgctgat actggaccaa tcataatgca
    28981 agatgtagtt aaggtaaatc aagatgatga tgcaaagaca cttgcaaaaa gagtgttaga
    29041 agttgaacat aggattttaa aagaaagtat aagtcttttt tgtgaaaata aaataaaact
    29101 tcaaggtagg agagtgttta taaatgagta agagagcttt aataagtgta actgacaaga
    29161 ctggtgtagt ggaatttgct aaagagttaa ataaattaga ttatgaaatt atatctacag
    29221 gaaatacatt taaaacatta aaagaaaatg gtgttaatgt aatgcaagtt gaagatgtta
    29281 caaattttcc agaaatatta gatggaagag taaaaacatt aaatccatat atacatggtg
    29341 gtatacttta taaaagagat aaagaatctc atgtagaaac tgtaaatgaa cacaaaatac
    29401 attcaataga tttagtagct gtaaatctat atgattttga aggaacttta aaagctggaa
    29461 aaagtcatga tgaaataatt gaaaatatag atattggtgg accatctatg atacgttctg
    29521 ctgccaaaaa ctataaggat gtaatagtag tagtagatat aaaagattat gattctataa
    29581 tagaaaaatt aaaaacagat acaatgacat tagaagacag aaaaaaatta tcatataaag
    29641 ctttctcaac tacaggaaga tatgatgcgt taatatctag ttattttgct ggagaagttg
    29701 gagatacgta tcctgacata ttaaatttaa ctttccaaaa agaacaaact ttaagatatg
    29761 gagaaaatcc acatcaaaat ggtttcttat attcacagtc aaatgcaaaa aatccaatct
    29821 taaattatga gcaattaggc ggtaaagaac tttcttttaa caacttaaat gatttacatg
    29881 gatgtttaga agtaatgaga gaatttaaag atagtgaaga agtagtttca gtagctataa
    29941 aacatgctaa ttcatgtggg gtagggttag gaaaagatgc ttttgaagca tatacaaaat
    30001 gttatgaagc ggataaggtt tcaatatttg gaggaatagt aggaataact tctactatag
    30061 ataaagctac agcagagaaa ttaaatgaaa tattcttaga aatagtagta gcatatgatt
    30121 ttgaaccaga agctttagag atacttaaac aaaagaaaaa tctaagaata ttaaaattag
    30181 ctaaaataga aaatagttta caaccatatg aaatgaaata tttagatgga aaattattga
    30241 tacaagatag aaacaatata ttagcagaaa aaagtgaaaa tgtaacaaag gaaaaaccaa
    30301 cagatgcaca acttaaggac atggaatttg gtatgagagt agtaaaaaat atgaaatcaa
    30361 atgcaattgc aatagtaaaa aatggacaaa ctctagcttt aggttgtgga caaacatcaa
    30421 gaatttgggc attaaaaaat gctcttgaaa ataacaaaga taaagatttt acaggagctg
    30481 ttttagcgtc agacgcattt ttcccatttg atgattgtgt aacattagct catgaatatg
    30541 gaatatcagc agtagttcaa ccaggtggct ctataaaaga taaagattca atagaagctt
    30601 gtgacaagta tgatatggtt atggtattta caggaataag acacttcaaa cactaaggag
    30661 gatattatga agatattggt tgtaggcggt ggcggaagag agcatgctat atgctggaaa
    30721 ctaagcaaag aaaaaaatgt agaaaaaatt tattgtgcac caggtaatgc aggaattgca
    30781 aacgtagcag aatgtgtaaa tataggtgat actaatatag aagaactttt aaaatttgcc
    30841 aaagaaaatg aaataggtct gacaatagta ggaccagaag taccactagt tatgggaata
    30901 gtagatgagt ttgaaaaaga aggattaaga gtatttggac ctaataaaaa atgtgctcaa
    30961 cttgaaggaa gtaaagcttt ttcaaaagaa tttatgataa aacataacat acctactgca
    31021 aaatataaag aatatacaaa cttagaagaa gctatatcag aaatagatag ttttggatat
    31081 ccagtagtaa taaaagcgga cggattagct gctggaaaag gtgttgtaat acctgaaaat
    31141 agagaagatg ctatagcaac tttaaaagaa atgatgtcag ataagaagtt tggagctgct
    31201 ggagataaaa tagtaattga agagttttta aaaggaatag aaacttcaat tctagcattt
    31261 gtagataatg atacaatagt tcctatggca agtgcaaaag accataaaaa agtaaacaac
    31321 tatgagcaag gtccaaacac tgggggaatg ggaacttttt cacctagtga aatatataca
    31381 gaagaattag caaataaagt aaaagagaca gtattagaaa aaactttaga aggcttcaaa
    31441 aaagatggac ttaattttaa aggtatttta tttgttggtc ttatgataac tgaagatgga
    31501 gaaaaagtac ttgaatataa tgtaagattt ggagaccctg agacacaatc tgttttattt
    31561 agattagaaa cagatttaca tgagataatg gaagctatac tagataataa gttaaaagat
    31621 atagaaataa actatagtga tgatgaagct gtgtgtgtta tgcttacatc aggagggtat
    31681 ccagacagtt atgaaaaagg gaaaattata actggtcttg aaaacttgga tgatgatata
    31741 gtagtattcc atagtggcac taagatgttt gatggtaatt tggttaccaa tggaggaaga
    31801 gtaattggta taactgcaaa gtcaactaca gttaaggatg cagcagaaaa agtttatgaa
    31861 aacataaaga agataaactt tgaaggaatg cactatagaa cagacatagg aagataattt
    31921 ttctaaaatg gaggataagg tatgttgaat actgaaaata aagactcaat ggttagaaga
    31981 gtattagttg aaaaaagaga aggttttgac cttgaggcta aagctttaaa aaaagactta
    32041 gtagaaagtt tacacataga taatatagaa aatttaagaa tattaaatag atatgatgta
    32101 gaaggaatat cagaagaagt ttatgaaaat gcagcaaaga caatattctc tgaaccaaat
    32161 ttagatgtag tatattatga agaaatacca aaattaaatg atgaaagagt atttgcaata
    32221 gaatttcttc ctggtcaata cgaccaaaga ggtgattggg cagctcaatg tgtacaaatt
    32281 gtaaatcaag ggataagacc tgctattaat acagcaaaag tttatatatt atcaggcaaa
    32341 ataactgatg aagagttttc taaaataaaa gattactgta taaatccagt agatagtaga
    32401 gaagcatctt tagaaaaacc agaaacgtta aaaatggaaa ctgaaatacc aacaacagtt
    32461 gaagtattag atggatttat agatttagat gaaaatggat taaaaacatt tgtaagtgaa
    32521 aaaggattag caatgacttt aggagactta caacacgttc aaaaatactt taaagataca
    32581 gaaaagagaa atccaactat aacagaaata aaagtattag atacttattg gtctgatcat
    32641 tgtagacata ctacttttat gactgaaata gaaaatgtaa agatagaaga tggtaagttt
    32701 aatgatatag taaaagaagc gtatcaaatg tatcttaact caagagacaa tgtatatgtg
    32761 aacagacata aagatatatg tttaatggat atagccactg ttgcagtaaa agaattaaag
    32821 aaaaatggga aattaaatga cctagatgaa agtgaagaaa taaatgcatg tagtataaac
    32881 gtagatgttg aagttgatgg taagatggaa aaatatctag taatgtttaa aaatgaaact
    32941 cacaaccatc caactgaaat agaaccattt ggtggagcag ctacttgttt aggaggagct
    33001 ataagagacc cattatcagg aagaagttat gtttatcaag caatgcgtgt tacaggaagt
    33061 gctgacccaa gaacgacttt agaagatact ttacctggaa aacttatgca aagaaaaata
    33121 actacagaag ctgctcatgg atatagttca tatggtaacc aaataggtct tacaactggg
    33181 caagttgcag aagtatatga tgaaaacttt gttgcaaaga gaatggaaat aggtgcagtt
    33241 atagcagcag caccaaaaga gaatgtagta agagaaagac ctgaagcagg agatgtaatc
    33301 gttcttcttg gaggaaaaac aggaagagat ggctgtggag gagcaactgg ttcatctaaa
    33361 gaacatagtg aagagtcaat cttaacttgt agtgcagaag ttcaaaaagg agatgctcct
    33421 aacgaaagaa aaatacaaag attctttaga aataaagaag ttgctcaaat gataaaaaga
    33481 tgtaatgatt ttggagcagg tggagtttgt gttgctatag gagagattgc tgatagctta
    33541 gatataaact tagacttagt tcctaaaaaa tatgatggac ttgatggaac tgagcttgca
    33601 atttcagagt cacaagagcg tatggcagta gccataaaaa aagaaaataa agataaattt
    33661 atacaattag cagtagaaga aaacttagaa gctacacatg tagctacagt aacagataca
    33721 ggatatttaa gaatgttctg gaatggaaaa gcaattgtag atataaatag agagttttta
    33781 gatacaaacg gagtaaaaca aactactgat gttcatgtta ctaaagtaga tgaagaaaat
    33841 acattcttta gctctaatga aatagtaaaa gatgttaagt gtgcaagtat gaaagacaag
    33901 tttacaaaag tactatctga ccttaatgtt tgttctcaaa aaggattagt agagatgttt
    33961 gataatacaa ttggtggtaa tacagtcctt atgccatttg gaggaaagta tcaagcgact
    34021 ccaacacaag gtatggttgc taagatacca gtacttggag gagaaactaa tacttctaca
    34081 ataatgactt atggatacaa tccaaaggta ggaaaatgga gcccattcca tggtgcctta
    34141 tatgcagtag tagaatctgt gtgtaaattg gttgctattg gaggaaatta tagtacaaca
    34201 agacttacat tccaagagta ttttgaaaaa cttggtaaca atccagaaaa atggggtaaa
    34261 ccattctcag cacttttagg agcattttat gcacaaagta aatttgagat acctgctata
    34321 ggtggaaaag acagtatgtc tggtacattt aaagatattg aagttccacc aacattagtt
    34381 tcatttgctg ttgacacagt agatgcgaag aaagtagtat ctccagaatt taaaaaagca
    34441 gactcaaaag tagtaatgtt atgtgtaaac aaggcagaaa atgatgttgt agattttgag
    34501 gaattaaaga gaaacttaga taaagtaaga gaacttatac atggaaataa agttttatca
    34561 acatatgcat taggatttgc aggtgtaggt gaagcaataa gtaaaatggc ttttggtaat
    34621 aaaataggat ttaagtttag tgaagaggct gaaaaagcat ttacagatga taaattattt
    34681 gaggctagtt atggaaatat agtacttgaa ttagcaaatg atgatttaag tatgttagaa
    34741 ggatacaatt atgttgtgct tggaagtaca gttaaagaag ctagtatatt tatcaaaggt
    34801 gaagaacttg cattagatga attatataaa gcacattgta gtactttaga gcctatattc
    34861 ccaactaaaa cagaagaagt aaaatcaaag atagaaacta taagttatat atcacaagga
    34921 gaagctaaaa aatcatcatt aagtatagct actccaagag tatttatacc agcattccct
    34981 ggaacaaact gtgaatatga ctctgcaaga gcatttgaaa gagcaggagc taatgcaagt
    35041 ataagagtat ttaagaattt aacttataaa gacatagaag attctataga tacaatagta
    35101 aacgaaataa aatcttctca aataataatg ttaccaggtg gatttagtgc tggtgatgag
    35161 ccagatggtt ctggtaaatt tatagctact gtatttagaa atcctagagt gcaagaagct
    35221 ataaatgaat ttttaactca aaaagatgga ctaatgttag gtatctgtaa tggattccaa
    35281 gtattaatta aattagggtt agttccatat ggagaaataa gagttccaag tgaaagtgct
    35341 ccaacactta cttacaataa tattggtcgc catcaagcta agattgctag aactagaatt
    35401 tcatctaata aatctccttg gttagctcaa actaatgttg gagatattca taatatagca
    35461 atttctcatg gagaaggtaa gtttgttgcc agtgaagatg ttatgagaga attaattgct
    35521 aatggacaag tagcaactca atatgttgac tttaataatg aagctactta tgatattgag
    35581 tttaatccaa atggttcatt ctatgctgtt gaaggtataa ctagtgctga tggtagagtg
    35641 tttggtaaaa tgggacattc tgaaagaatt ggtgaggaag tatataagaa tattataggt
    35701 gaaaaagacc aaaagatatt tgaatctgga gttaaatatt ttagataaag ctttgatgtt
    35761 taattgatag ctagaatata taatttagat atttagattt aaagagatgt aataatatga
    35821 tgataatcat ttaatattac atctcttttt tatttatcta agaaataata agttcaacct
    35881 aagttaaaat acaagctgtg ttataattaa ttattaagta aaattgaata tttattggag
    35941 ggcaacataa ttaatgaaaa tattaataac agggtctaat ggtcaattag gaaaagaatt
    36001 ggttaaccaa ttagaagcaa ttaatcaaag tataaaccaa ccaaaatatg ttatattagc
    36061 tacaacaaga agtgatttgg atatatccaa tcagactaat gtagataatt ttattttgca
    36121 taataaacct gatgtagttg taaactgtgc agcatataca aaggttgatg catgtgaaga
    36181 taatatcgaa attgcataca aaataaatgc tttaggagtg agaaatctag caatagcatc
    36241 agaaaaagtt aatgctaagc ttattcacat atcaactgac tatgtattca atggtttttc
    36301 taaatatcca tatagggaag acaataaaac tgaacccaat tctgtatatg gaaaaagtaa
    36361 acttatggga gaaaaatttg ttgaacaatt ctcacataag tactttatat tgagaacagc
    36421 atggttatat ggtaatggga ataattttgt aaagaccatg ataaaacttt ctttagaaaa
    36481 taaagaggtt aatgtggtta atgaccagtt tggaactcca acaagtacag tagacttagc
    36541 aaaaattata ataagaatca tggaaacaga acattatgga gtttatcatg ctacatgtga
    36601 aggtgagtgt agttggtatg attttgccaa aaagatattt aaactaaaaa atatagatat
    36661 aaaagtaaat ccaattaaga gtaacgaatt taaatgtaag gctccaagac cactatattc
    36721 tgtattagat aattttatgt tgaagttaat tggtttaaat tcttttagaa agtgggaaga
    36781 atccattgaa gaatatttag aaagatatga tataaatgaa aagtaaatgt attattttga
    36841 gaaaagaaaa taagatatta taaaaaatat aaatatttct tttatttatc cgataatcat
    36901 aatatgacaa aaacaaattt aaggatggaa aaagatgaaa ggaattattt tagcaggagg
    36961 gtctggtaca agactatatc ctataacaaa atgtatatca aaacaaacac ttccaatata
    37021 cgataaacca atgatatatt accctatgtc ggttcttatg ttggcaggga tacaagatat
    37081 attaataata tctacaccaa gagatataaa agcatttgaa gaattatttg gagatggaag
    37141 ttcactaggg attaacataa catatgcaat tcaggagaaa gcaaatggaa ttgcagaagc
    37201 gtttataata ggagaagaat ttataggaaa tgacagagtg tctcttgtat taggggataa
    37261 tatattttat ggatatggat ttagtgaaag gttggagaat gcagttaaaa gaaaaggagc
    37321 aactatattt gggtatcatg taagtaatcc aaattcgttt ggagttgtag aatttgataa
    37381 ggattttaat gtattgtcaa tagaagaaaa acctacagtt cctaaatcta attatgctat
    37441 accaggatta tatttttatg ataatgatgt tgtagagata gcaaagctag ttgaaccgtc
    37501 agatagaggt gaattagaaa taacctctat aaacagtgaa tatctaaaac gaggaaaact
    37561 aaaagtggaa cttctaggaa gaggtatggc ttggcttgat actggtacac ataaaggtct
    37621 attagatgct tctaattatg ttgaagtggt tcaaacaaga cagggattgt atatagcatg
    37681 tttagaagag attgcatata caaaaggata tataagtaga gaacaattaa tgaaactagc
    37741 caagccactg ataaaaactg aatatggtca atatctatta aaattggcta gtgaagatat
    37801 gtaatatggt agataaaatt tattataaat tttattaagg gagtttatta taatgggaaa
    37861 aatcaatgtt ataaagacta aaatagaagg attatatata gtcgaaccaa atgtatttta
    37921 tgatgaaaga ggatatttta tggaaagcta taataaaaag gattttatag agcagggtct
    37981 tgatatgtgt tttattcaag ataatgagtc tagctcaaga aaaggcgttt taagaggaat
    38041 gcattttcag gttaaatatc ctcaaggaaa attagtcaga gttacagagg gagaagtttt
    38101 cgatgttgca gttgatttaa ggaaagattc acaaacattt gggaaatggg aaggtgtaat
    38161 attgtctgat aagaataaaa aacaatttta tattccagaa gggtttgcac atggattttt
    38221 agttttatca gaaaaagcag tatttagtta caaatgtaca aattattatt acccagaatt
    38281 tgagaatggt tttatatgga atgataagca aatatctatt gagtggcctt taaaaggaat
    38341 tgaagaaata tttttatcag aaaaggacaa aaaacaaaaa agttttaaag atatttgtac
    38401 aagacgttaa taaaaattta ttagaattaa catttaggag aaaaaatatg aaaaaaatac
    38461 tgataactgg aggagcagga tttattggga gtaattttat acattatatg cttaacaagt
    38521 atgtagatta ttttattgtt aacctagact tgttgactta tgctggtaat ttagagacat
    38581 taatagaaat acaagacaat tccaattata aatttgttaa aggagatatt tcaaataggg
    38641 agcaggtgta taagctattt gaagaagaaa ggtttgatat agttgttaac tttgccgctg
    38701 aatctcatgt agataggtca gttgagaatc ctgatttatt tattaaaaca aacattatag
    38761 gaacacaagt acttttagat gcatctataa aatatggagt taaaaggtat catcaaatat
    38821 ctacagacga agtgtatggt gatttaccaa ttgatagaaa ggatttattc tttacagaac
    38881 aatcttctat caatccaagt tctccatatt cagcttctaa agcatcagca gatttattgg
    38941 taaattctta ttatagaaca tatggattgt taacaactat atctaggtgt tccaacaatt
    39001 atgggccata tcattttcct gaaaaattga ttcctcttat gattttaaat gctttggaaa
    39061 acaaacaatt gccagtatat gggaatgggg aaaatgtaag agattggtta catgtatatg
    39121 accattgtac tgctatagac ttaataatac ataaaggaaa tataggggag atttacaata
    39181 taggaggtca taatgaaaga agtaatctag aagtagtaaa agtgatatta aatcttttag
    39241 gtaaatctga agagttaata tcctatgtaa atgatagacc tggtcatgat ttaagatatg
    39301 ctattgatgc aactaaaata gagaatgagt taggttggaa ggcaaaatat gactttgatt
    39361 tgggtataaa agaaactgtt aagtggtata tagaaaatga atcttggtgg aaagctgttt
    39421 tatcagtata actttaaaat ttagaaaggg gcgttttata ttgaatgaga taagttcact
    39481 aattaatata ttagcattga ctcaattatc tggtagtaat actacaaatc aatgtaattg
    39541 tacatataat aattcatctg gatttgatat gattatgatg accttgttaa aagcattatc
    39601 acaaaataat caacatactt ctaatagcta caatttattg tctaattctg agaatttatt
    39661 taatgaactt gataatgtag taaataatac cactagtaga tttatagatg ttgatacaaa
    39721 agataaaaat gtaaagttga gaattgaaaa tgctgtagat caagcatcaa aaaaatataa
    39781 cgtagattca aatcttataa aagcaataat taaagttgaa tcagatttta atccaaatac
    39841 cgtttcttct gctggtgcta agggtcttat gcaacttatg ccagaaaact gcagagactt
    39901 aggagttaca gaccctttta atatagaaca gaatatagat gctggaacta gacatattaa
    39961 ggaatacatt gatatgtttg gagggagcat agaaatggga ttgatggcat ataatggtgg
    40021 tcctggaaga atgaaaagta gaggagtaga atcaatctct gacctgtata aaatgccaaa
    40081 agaaacacaa aattatattc ctaaggttat gaaatattat agagggtagg ctttattatg
    40141 ggaataaata tagataagct aaacataagt ccaagtataa atatggaggt taaaaaacta
    40201 aaagagagta ataaattttc tgacaaatta aactctttaa aacaatcttc ttcattggaa
    40261 gatataaaac gaaatttgga aagtgtaaaa aaggcaggag aaaggcttgt acttactcaa
    40321 aactatggcg atattagtat atataaaaat gcagtaaaag aatacctaaa atctgttgta
    40381 gataatatgt attcacttga taaaaatagt agcttttggg agcatcagta ttataagaat
    40441 gtaaagattg ttgatagtaa acttgaggat atgactagta agttaattag tgaagaaaaa
    40501 gaaaacatag atattgtttc tactgttgac atgatacaag gcttattgat agatatgtat
    40561 agataaggtt atacaaggag aaaaatttta tgaatagcaa aaaagaggat atatatgaat
    40621 tgaattttgg gcaattaata gaagaaaaat ctggtgttat agaagaaaat caaaatgttt
    40681 ttaatgcaaa agtaaatgta gctgtttcta taggaaatac aacagaaaca ataaaaaata
    40741 tattagattt aaaagaaggc tctataataa aattaagtaa gaatgtggat gaaaaattag
    40801 atatatatgc aaacgataga ttgtttgctt atggagaaag cattattaca aatgagaggt
    40861 tatctgtaag attatctaaa atagaagatc cagatgtaaa ttagcatttt aaatagtatc
    40921 cctttaggct attctgtatg agtttagcta aggggatatt tttataaaaa atttaaaata
    40981 tgtgtgaatt atataaatat ttttatttta tgagcgataa ctaaattata agtatgtaat
    41041 tttggaggtg aaactatgga tattaaaaat gtaagttcaa acattgtagt gaataattat
    41101 ttaaagaata catctggtat aaaaaaagtg gaagaggtta aaaaaattaa taaaacagac
    41161 aagatagagt tatctaaatt tgcaaaggaa atggcaagtg tgtcaaatat gagtgatgag
    41221 aatattagaa ataaaaaagt cgatgaaata aaaaatgcat tagaaaatgg aacttacaaa
    41281 ataaaaccaa aagaaattgc gaaaaaaatg atagaggata tgcgaggata aagtcatgat
    41341 tacagactta aaagttataa tatatgaaga aaaaaatata attagtaaga tgatggaatt
    41401 attaaaagaa caatttgatt atatagttga aaaagactta gaaaatttaa atatgttaaa
    41461 tcctaaacta gaagatatta gcagggagct tgcatccata gaaataaaga gaagacaact
    41521 ttttggtgat gatatttcaa tgagtgaagt tgttgaaaat agtaatgatg gatacttaaa
    41581 agaaatatat acagacttga aacacattct tgctttagct aaaaatcaac aagaatcaaa
    41641 tgattctcta ataaagaaag aacttatttt tacgaaaaaa atgattaatt tcataaaacc
    41701 agctgataag aaaactacaa cttataattc ttatggaaat attagaaaat aaatattagg
    41761 aggagaaata tggcaggatt attttccatt ttaaatacag ctaattcagg aatgaatgcg
    41821 caccaaaaag caatacagac aatttctcat aatataagta atctagatac agacggttat
    41881 tctaggcaaa ggaccgagtt tgccacaaat agtccaatgt atatgcctag tttgagtaat
    41941 tcaattgcaa gaggacaatt agggactgga gtacatgtaa cggatgtaac aagagctaga
    42001 aatagttttt atgattacca atttagggca gaagctcata agtatggtaa gacagtttca
    42061 aaatatgatt attacaatac tatagaaact atactaaatg aaccatcaga ctatggaata
    42121 tctgcaggta tagatgattt ttttaaagga tgggagtcat tatcaaagga tataaatagt
    42181 gacagtaaaa aaagtctagt ggtagaaaac gcatctaatt tagcaacttt aataagtgaa
    42241 agttataaga agcttgataa gttaaaagaa gatatagatt ctaatataga cactgagata
    42301 aaacaaataa atgacatgtt aaaaagtctt gaagatttaa ataaatctat tgatattata
    42361 tctggttctg gctctacacc aaatgattta cttgatgaaa gagatagaat tttagataac
    42421 ttgagtttta aactagactt tgaaaatagt gatgttaaaa atatgcttgc agatggtaaa
    42481 ttagaactta atgaattaaa aaatccagat ggaacttgga aaacaggtat atcagggacc
    42541 ttacaaggct tgtttgaaat gcatggtaag attgatacat ataaaagcga tttaaaagat
    42601 gtatctgatg gattagctaa acagataaat gatgtttata atacgtctgc aggaataaca
    42661 gtaacagatt tttttataac ttcaaatgta gatggtgaag atattataaa gataaatcca
    42721 gctataaaga gtaacccaaa tgaattaaag cttactgctg atgaagcttc aaaaattgct
    42781 aagttaaagg atgaaaaaat agatattggg gtggctggtg gaaaagtaag tacaataagt
    42841 gaccactata aagcctttgc agaatcaatc ggtttagatt ctcaaaaagt aaatcaagat
    42901 gaagcaaatc aacgtaaaat tataaataat attgataact caagaatgag tgtttcaggt
    42961 gtatctttgg atgaagaaat gacagagctt ataaaaatac aacgttcata tcaagctagt
    43021 gcaaaagtta tgtcaacagc tgtgcaacta ctggatgttg taataaatgg aataatttaa
    43081 tagaaggggg aatttataat gagagtcagt acaggtatga tgtctagcag ctatctaaac
    43141 tcactacaag ataatctaca aagattggat aaggttaata gacaagttaa tacaacaaaa
    43201 gaaataaaca agctatcaga taatccatat aaagcaataa agatattaaa ctcaaaaagt
    43261 gaaataaaga ctatggagac ttatgttgag aattgtaaag atacagggaa ttggttagaa
    43321 actactgata ctgcattaga tcagcttgga aaattattat cagacataaa gaaaactttg
    43381 gtggcaagtg gtgatggtgc atactcagat gatgaattaa agactcttag taatgaaact
    43441 aatgaaaaaa tgaaagaaat tgcaaatgct ttaaatgcaa cacatgaagg gaagtacata
    43501 ttttcaggtt caaatacggg ggtaccacct gttgaatgta tagataatgc tgatggttca
    43561 gtgagtttaa agtttaattc tagtctaaat cttaataaat taaatgactc tttgagtatg
    43621 gatatagctc aaggaataag tgtagattat aacgttaaat tgagtagcct tggatttgac
    43681 ccaacaaaaa ctgacccatt tgaagagtta aataacatat caaaaaaatt agcaaatcca
    43741 gatgctgatg ctataaaaga gcttacaaca acttgtttgg gcgatatgga acaactaata
    43801 gaaaatacag taaatgttag gtctatatat gggacaaaag caaatacagt agaggctatg
    43861 aaggaaaaaa acgatgatag tttgatacag ttaaaggata ttttgtcaca aaatgaagaa
    43921 atagattatg gtgaaaaact tgttcaatta aaggcagcag agttaactta tcaagcttca
    43981 ctacaaacag gaggaaagtt atttaatgta tctatattag attacatata ataaaataac
    44041 gcagatatga tgaaggttac attaaaaaaa ggtatattag gttttgaaaa tttaaaagaa
    44101 tatgagcttt tagatataga agataatgat tatttaaaag aatttaattc tactgaagaa
    44161 gaaggtatag gatttgttgt tgtatctcca tttgagatta tcaatgaata tgaaatagtt
    44221 ttaaatcagg aaacaataga aaaactagaa gtgaaatctc caaaggatgt tgtattattt
    44281 aatataatta ctcttggtca gacatttgaa gaatcaactg tgaacatgaa agctcctata
    44341 gtgataaata taaaaactaa ttttggaatg caaataattt tacaggatga taaatattca
    44401 ataaggcatc cattattgag aggtgataat ggatgctagt aatttcaaga aaaaaagatg
    44461 aagcagtact tataggagaa agcatagaag taaaaattgt aggagtagat ggaaacaatg
    44521 taaaactagc tatatcagcg cctaacaata taagtatatt aagaaaagaa atatacgaaa
    44581 aagtaaagag tgagaatata aaagctacaa ataaaaatat aaaaatttta aagtcattaa
    44641 aataataagc ttggaggaag taatatatgt atggagaaaa tccttataat tcttataaac
    44701 aaaatgctgt ttttatggca tcaaaggaac aattgttact tatgcttgtt gatggagcag
    44761 taaaatatac caaaatagcc aaaacagcta tcttagataa aaatacacaa aaagcgcata
    44821 gagagcttat aagagttcag gatatattta cagaactaat ggttacatta gaccaaaatg
    44881 caggtcaatg ggcaaaggat atgtacagag tttatgattt tgtaagatat gaactttcaa
    44941 gagctaatat tagaaaagac attcaaataa tagataatgt gttgcctgta atagaacaaa
    45001 ttaaagatac ttggcatgaa gctgataaaa aaagtaaaga agaaagaagt aggtacaaat
    45061 aatggaatta aatttagctg aattagataa gttatcaaaa gaggaattac tattgatgct
    45121 tgtagatgga acagtaaaat ataccaatat atccaaagaa gctcttttaa ataacgacta
    45181 tttgaaagca cataatgaac ttgtaagagt tcaaaatata tttacagaac taatgactac
    45241 attagaccaa gatgcaggtc aatgggcaaa ggatatgtat aaagtttatg aatttataaa
    45301 atctgaatta gcaatagctg atgaaaataa agatattaaa ataattgatg atatattgcc
    45361 aatagtaaaa caaattagag atacatggca tgaagtttac aatcaactaa aaatataatt
    45421 ggatggaggg ataaaggtat gtcaagtata agtcctataa gagttacagg tctttcagga
    45481 aattttgata tggaaggcat aatcgaagct agtatgatta gagacaagga aaaagttgat
    45541 aaagcaaaac aagaacaaca aatcgttaaa tggaagcaag aaatatatag aaatgttata
    45601 caagaatcaa aagatcttta tgataaatat ctaagcgtaa attctcctaa tagtatagta
    45661 agtgaaaaag catactcttc tacaagaata accagttctg atgaaagtat tatagtagca
    45721 aaaggctcag ctggtgcaga aaaaataaat tatcaatttg cagtttctca aatggctgaa
    45781 ccagcaaaat ttactattaa attaaattca agtgaaccta ttgttcaaca gtttcctcca
    45841 aatgctagtg gagcgagttc tttaactata ggagatgtaa atataccaat atctgaacaa
    45901 gatactacaa gtactattgt aagtaagata aactcccttt gcgcagataa tgatataaag
    45961 gcttcttata gtgagatgac aggtgaattg attatttcaa gaaaacagac tggttcgtca
    46021 tcagacatta atttaagagt aattggaaat gacaatttag ctcagcaaat tgctaatgat
    46081 aatggtatca catttataaa tgatgctggt ggaaacaaag tggcaaatgt atatggaaag
    46141 aatctagaag ctgatgtaac tgatgaacat ggaagagtaa ctcatataag taaagaacaa
    46201 aattcattta atatagataa tattgactat aatgtaaatt caaaaggaac tgcaaagttg
    46261 acttctgtca ctgatactga agaagctgtt aaaaatatgc aagcatttgt ggatgattat
    46321 aataaactga tggacaaggt ctatggttta gttactacta aaaaaccaaa agattatccg
    46381 cctcttacag atgcccaaaa agaagatatg acaactgaag aaatagaaaa atgggaaaag
    46441 aaagctaaag aaggtatact tagaaatgat gatgagttaa gaggttttgt tgaagatatt
    46501 caatctgcat tttttggaga tggaaaaaat attattgcat taagaaaact aggtatcaat
    46561 gaaagtgaaa attacaataa aaaaggtcaa atatcattta atgcagatac tttttcaaag
    46621 gctcttatag atgatagtga taaggtatac aaaacactag caggttattc ttcgaattat
    46681 gatgataagg gaatgtttga aaagctaaaa gatattgtat atgaatattc tggaagttca
    46741 acttctaaac ttcctaaaaa agcaggtata gaaaaaactg cttctgctag tgaaaatgta
    46801 tattcaaaac aaattgcaga gcaagaaaga aatataagca ggttagttga aaaaatgaat
    46861 gataaagaga aaagacttta tgctaaatat tcagccttag aatctttgtt gaatcagtat
    46921 tcttcccaaa tgaattattt ctcacaagca cagggtaatt aattatggat aaattaaaag
    46981 aaaaattaaa tttatataaa gatatatctt tacaaattat aaatttgatt gaaaaggaag
    47041 aatatataaa gataagtatt aagttaggtg aaagacaaga gattataaat agtgtaagtg
    47101 aaattgatag aaatgatttt atacagcttt ataatagaat ggaattaatt gaaattgata
    47161 gcaggataag agatatttta caaggacaat tattagaagt aaaaaaagaa ttacatgagt
    47221 ataagcttac taaacaagtg aacacaatgt attataactt aaatagagaa aaagtaaata
    47281 tttttaataa aaaagtataa agttatgtac catcttgtcc gattatataa atgaagaatt
    47341 aataaaaaag attaaaagta gaaatgacaa ggatgtcaac tatactaagg agggtaaaat
    47401 aatgagagtt aatacaaatg taagtgcttt gatagcaaat aaccaaatgg gaagaaacgt
    47461 aaatgcacaa agtaagtcta tggagaagct atcttctggt gttagaatta agagagctgc
    47521 tgacgatgct gctgggcttg ctatatctga gaaaatgaga gctcaaataa aaggtttaga
    47581 ccaagcagga agaaacgttc aagatggtat atctgttgta caaacagcag aaggtgcatt
    47641 agaagaaact ggtaacatac tacaaagaat gagaacttta tcagtacaat cttcaaatga
    47701 aactaatact gctgaagaaa gacaaaagat agctgatgag ttactacaat taaaagatga
    47761 agttgaaaga atatcaagct caattgagtt taatggtaag aaattacttg atggaagttc
    47821 tacagaaata agattacaag ttggagcaaa ctttggaaca aatgttgcag gaacatctaa
    47881 caacaacaat gaaataaaag ttgctctagt aaatacttca agtataatga gtaaagcagg
    47941 tataacaagt tctacaatag caagcttaaa tgcagatgga acttctggaa caaatgcagc
    48001 taaacaaatg gtatctagct tagatgtagc tcttaaagaa ttaaatacat caagagcaaa
    48061 attaggggca caacaaaata gactagaatc aactcaaaac aacttaaata atactataga
    48121 aaatgttaca gcagctgaat caagaataag agatacagat gttgcttcag aaatggttaa
    48181 cttatctaaa atgaatatat tagttcaagc atcacagtca atgcttgctc aagctaatca
    48241 acaaccacaa ggagttttac aattattagg ataaaataat tttgtatatt ggatatagaa
    48301 gaaagggtaa ggctttgctt tactcctttc tttttttaca aatatacttt tgaaaggaaa
    48361 atttatatgt tacttagtat agttatgatt gttaaaaatg aagaaaaaat acttgaaaaa
    48421 actttaaaat cattaaccac attaagaaat tctatagaaa gtgaacttat aatagtcgat
    48481 acaggttcta cagatgatac tataaaaata tctaagaagt acacggaaaa agtgtatttt
    48541 cataattgga ataatgattt ttctagtatg agaaatatat caatatccta tgctaaaggt
    48601 gaatggttac ttatattaga tgcagatgaa atactaattg attcttcaac tattgtaaaa
    48661 ttttttaaag atggtcttga taaaaaattt aattctgctt caatacaatt aaaaaatctt
    48721 tactcatatg ataaaaaatt atatggatat tgttcggtgc ttagactttt taaaaacgtt
    48781 gattttagat accatggtaa agtacatgaa caaccaatat acaaaaaccc tatatttaat
    48841 aatgttgctg attttgaaca ttatggatat ttgtttgaag atgaagaaat aagattaaat
    48901 aaggtgaaaa gaaatgaaaa actattattt caagagttaa aagagaatga taattctcca
    48961 tatacaaact atcaattagg gaaaaatttt attatattag gaaaatatca ggaggcttta
    49021 tactatcttg agaaatctta tgaattatat tctaaactag aattggcacc tggttacttg
    49081 ataacaagcc ttgtaaaaac atatttatat ttaggaaaac ataagaagtg tgaaagattg
    49141 tgcttaaagt atattaagaa agacatgaat aatattgata tatattatta tattgcacaa
    49201 gcacaagtag atttaggaaa gtatgaaaat agtatagatt cgtataagag atatatttac
    49261 ttgttagata attatgaaat aagtacacaa gcaaatagtt tattttcaga cactgatact
    49321 gtagggctta gagatgaggc tattattaca ctgataaaga tttattataa gcttgaaaaa
    49381 tatgagtttg taatttcaga gtataataac attgaagatg tggaaaagaa aaagaatgtg
    49441 tactttagct tatttatgtc actatataaa ttgaatagat ttgaagatat aaaaaattat
    49501 tataaagaag tttcaaattc taaaattgaa aaaaatagtt tttatagaaa tatagaagaa
    49561 gttataaata atattaaaga ggatgaaaaa gagtatgtat ataaaatcct ttgtgacatt
    49621 gaaggtaatt atggcatttt aaatcaaata aggataaata aatgtgtatc tatagataaa
    49681 tgtaaagaaa tactcaatga agaaaaggaa ataatttatg catatattat aaaaatagct
    49741 tttgaagaga agattgattt actagatatt ttttatgaaa tggaatatgt atggatagag
    49801 aaatatctaa aatatctttt agcattagaa agaagtttta atttagtact atataagtac
    49861 ataattagtc gtccaaatac atcagatatg gaaaagataa gagtatataa agctatatct
    49921 aaagtagttt tagaaagtat aagcttaagt gatgaaaaat ataaggagat tttttatctt
    49981 tatataatgt attcttataa gtacataaga tacatatata gcaatttaag tgattttgaa
    50041 ttaataaaat ttgtttgtaa tgatttagat aagttcacta tagaatttaa gcatctactt
    50101 gatattaaaa ataaagtaaa taatgctaat gaaaaattag agtatataca tagtatgagg
    50161 aaattactaa atgagtatcc tttttataat aaaataataa aaatacttat aggtgaatta
    50221 gaagaaaata taaaagaaag tgaagaattt aaggatttaa aagatagttt tattattagt
    50281 atagaaaata tgattgaaac tggcaaaata aatgatgcga aattattggt agatgactat
    50341 tcaaaaacat ttgtggatga tataaagatt ttaaatataa agggaatttt atacatgttt
    50401 gaaaataagc ttgataaagc tgattttatg ttaaaaaagg cattatcatt agatgtagaa
    50461 aatgaagata ctatatataa tatagaatac ttaaaaagtt taagataagt caaaaatagg
    50521 agaattgaag aatgaatata ccaatagtgg ttaatgaaaa atctaaagac ataataaaag
    50581 attggcaata tacatgtaca aatgaagata taaaatttac aagcataata atattgacat
    50641 ataatcaaat agaatatact aaattatgta ttgaaagtat taggaaattt accccaaaga
    50701 ataaatatga aataataata attgataata actcttctga tggaacagtt gagtggttaa
    50761 agggacaatc tgatataaaa tctgtgtata ataacaaaaa cttaggattt ccaaaaggat
    50821 gcaatcaagg tattgagtta gctactggtg aaaacatatt gttgttaaat aatgatgtaa
    50881 tagttactcc aaattggctc tataatttga ataaagcttt atggtctcaa gataatatag
    50941 gtgctgtagg acctattacg aatgcatgtt catattatca gcaaattgat gttgattata
    51001 agtcaattga ggacatgttt atatttgcac acaaaataaa taaatctaat attaacctat
    51061 ggaaatatag attgaagtta gttggatttt gcatgttaat aaaaaaaact gttctggata
    51121 atgtaggggt tttagatgaa ttattcacac ctggaaattt tgaagatgat gatttatctt
    51181 ttaggatgat agagtcagga tataagttat tattatgcca ggatactttt atacaccatt
    51241 ttggaagtgt gtcttttaaa gaaaatcgta ataaatatac agatataatg tatattaata
    51301 gaagaaaatt tgaaactaag tggggattta atccagaata tagtggaatg ataagaacag
    51361 atttgatttc taaaatagat gatagtttgg aggcaaatat taatgtttta gaaataggat
    51421 gcggtatagg ggctactctt ttagaaataa aaaatatata taaaaatgca tcaatatatg
    51481 gaatagaaat tagtgagtca gcaggtaaac ttgcaaagta tagtgcagat gtacttatag
    51541 caaatataga aaaagtaaaa ttggattata aaaaagattt ttttgattat ataatattgg
    51601 gagatgtact tgaacatttg attgacccat ggaagatagt caatgaattg aaacaatatc
    51661 taaagaagga tggttatctg gtatctagta taccaaatat tatgcatgtt tctgttttaa
    51721 gaaatcttgt gttaggtaat tttacatatg aagattcagg aattttggac aagactcatt
    51781 taaggttttt tacattaaat gagataacaa aaatgtttaa tgatagtaat tacataatta
    51841 atagtattac agctactagt atgccacttt cggaaattga taatagcttc attgatacaa
    51901 tatgtaagga aagctgtaaa gaaatgagac aacagtacga atcttatcaa tatatagtaa
    51961 aagcctctaa aatcctagat actaaaagat attctagtat tagtatgatt aatttaaaat
    52021 acgctttaat gagaattgat aatgaattag atgtagatag taatttaagt tatatatttg
    52081 ataattataa tataactgaa ccatgttttg ttgatgatat tgaatatcta attgatacat
    52141 ttgtgataaa taaagcaact ctattaaata gattaggagt tgaggcattt aacagaggtc
    52201 taggagattt tagtataaac atgtttatga cagtattaga gatggataga gatgatattg
    52261 actcaatata taatataaca agtgtattat gtgaattaga agaatttgat actgcttata
    52321 atttaattaa aaatagtagc gaaaaagtac agagtgaaag tgatatacaa gagatacttt
    52381 gttttattga ggggaagaaa tatgaataat gataagatat gttttataac ctgtgtaaat
    52441 gatgaaaggc tttatgaaga atgtcttgta tatataaata gcctagacat tcctaaaaac
    52501 tttagtatag aaacagtagc tttaagagga gccgattcta ttgcctctgc ttataataaa
    52561 gctatgagag aaacagattc taagtataag gtatacttac atcaagatac ttttataatt
    52621 aataaaaatt tcatacatga tattttagag atatttaaaa aaaatacaga tgtcggaatg
    52681 attggtgtag ctggagtaaa agatatgcct gtgaatggaa tttggtggga ttctgataaa
    52741 aaagcaggga aagtatatga tagtcataca ggtaaaatgg atatttatga atttagtaac
    52801 tttgaagaat gttttaatga agttatggct atagatggat taattatgat tactcaatat
    52861 gatgtatttt ggagagagga taagtttgat gggtggcatt tttatgattt gtcacagagt
    52921 atggagttta gacaaaataa atacaaagtt attgtaccaa aacaaaataa gccttggtgt
    52981 atgcatgatt ctggagtagt aaatataaat aatggatatg atgaatatag gataaaattt
    53041 gtaaaagagt acataaatct tgatttatat agagaaaatt tttatgaatt tgataagaag
    53101 aaagcaagta ccatacttaa gagtaataag catgtaatgg attgtatgaa agaggagctt
    53161 acagaacaat taagattaaa gaattacaag gatgttttag gtattgtttc taaaattgct
    53221 catttttctg tttttaatca tactggtttg tattcttgtg aagaatgtga gagagcattg
    53281 ctagaatgtg caaataattt accagaaata gaaaatacga aattatttac aaaaaaagat
    53341 ttaaaaagaa gaaaagtatt acatgtttta agtgaaggat attcaacagg aggtcataca
    53401 agactagtta aaaattggat tgaaattgac aaagactctg ttcattcagt tgtaactaca
    53461 tggcaatcag atacactgcc agactggtta ttaaaagcaa taaatgatag tggtggcgaa
    53521 gttatatctt tggatttaat ttcagatgat tatttaaaaa gagctgtagc tttgaggaaa
    53581 atagcttatg actgggctga tatagttatt ttatatgttc atatgtggga tacaatacct
    53641 gttgttgctt ttggagttga tgggaaaata cctattttac atgttaatca ctatgatagt
    53701 actttttggt tagggacaag tattgcagat attgtcattg attttagcga aactagtcaa
    53761 ttaattacat tagataaaag aggcatagat aaatctgaaa tattaccaat gccattaaaa
    53821 gaaaaagaag tattttcaaa atctgaagtt agaaaacgat ataatttaga ggatgatgtg
    53881 acaataatat tgactattgc tagtgaaaga aaatacaata gtgtaaatga tattaattac
    53941 tttaaaattg ctaaaacatt gattgaaaat acagataata caattattat tgttgtagga
    54001 gttgatacag agaatctcta ttggaaaact ttaagtaatg ttacagataa tagagttata
    54061 tgttttggaa caacagcaaa tatagatgat ttttataaga tttcggatat atacctagag
    54121 tctttcatgg taggaagtca tacttcaaaa ttagatgcaa ttttatatga tttaattcct
    54181 gttaagttta aaaatgaagt ttcaccaatt tttacaaata tgtggaattt tatagataag
    54241 tttgattata agaatataaa agaggttata gacatgataa gaaggtacaa tactagtgaa
    54301 tttgacaggg ataagataaa agcaaaacaa tcggaaataa aacattttgt tatagataaa
    54361 cattgtattg aaataaaaaa ctatatagac aaaatatata atgaagttaa tcatcataaa
    54421 gttaagtatg atttatataa aaatgatgaa atcgaggact atcagctttt tgtagcatta
    54481 tatggctata tggtaaaaaa taaaaacatg tcataggtgg taaaatgaac aatattcata
    54541 tcaataaatt tgaaaaaagc tgtgaaaaaa actgggatta ttttgtagaa aataaatcta
    54601 taaatggtac atttctgcaa actagaaatt tccttaatta tcatgaggag ggaaaattca
    54661 ctgaccactc attaataata tgtaaaggtg aagaaatact agcagtcgta cctgcatgtg
    54721 aaacttatga agatggtgaa agaatatttt tttctcattt agggagtact tttggtggca
    54781 ttataataag aagtggtttt aatgatatta ggcatgtaaa tgccattaca aataagttag
    54841 aaatatattt acaggaacaa aatttcgata aagtatattt aaaaaataca tcaagaatat
    54901 tttgtaaaga ggatacttca ttactagaat attttttatt taagaataat tacatgtttt
    54961 atgatgaatt aagtatgttt ttagaattaa gtaagtataa agaagatata ttagccaatt
    55021 ttaaatacag taaaagaaga gattttaaat attctttgaa gaataatctt acctttaaaa
    55081 gactgtatag tgatgaagat atagtttgtt tttttaattt actttctaat tgtttagata
    55141 gtaaaggagc taaagtaata cattcagtag aagaactttt ggagtttaaa aataatagat
    55201 taaaagatat tgtagaattt tatgcagtat atattgatga cattatgatt tgtgggagca
    55261 tggtatttaa ctttcaagaa agagtttatc atactcaata tctagcatca aattcgacat
    55321 ataataaata ttatccaatg atatttttat actataatct aataaaagat gctttagaga
    55381 gaaattttaa gtatctttct tttggaatta gcactctaaa tagaggcaaa tacttagatg
    55441 agggtttagc tacatttaaa gaaggttttg gttcaagtgc aatttgtaac agaacatact
    55501 ataaaaatat aaataagtga gaatcatgtt ttatagagtt tttagagtat agtaaatatc
    55561 tagtactata atattacata aaaataatta gtttataaag aaggtttgta tatgaaaaga
    55621 ttaatgattt taggctcaat taagtatttt gagaatattg ttatgtcagc taaaagagag
    55681 ggaatataca caattgtttg tgataataga attgatactc ctgcgaaaaa gatttgtgat
    55741 gaagcaatag atgttgatgt atttgatttt gataaaataa agaatatagc tatagataaa
    55801 aagatagatg gaattttaac tggatttaca gattctttaa tgaagccata tgtttatatt
    55861 gcaaatgaac taaatttgcc atgtgtgatt tcttgcaatc aacttgaatc tgtaactaat
    55921 aaggctgtta tgaaaaatta ttttaaaaat aatggaatac ctacaactga ttattgtatt
    55981 attgaaagtt tgaaagattt agaaaaaata caaggattaa attttccact tgtaataaaa
    56041 cctgttgatg gttatggttc aagaggtgta tattttgtat caaacataga agaattaata
    56101 gaaaaatttg aatattctaa ggaagcctcg caagatggac aagtaataat tgaggaattt
    56161 tatgaaagtg aggaaataca aggactagct tgggttcata atggagagtc acatgtattt
    56221 tatattggag atagagagct tgtaaatata catacaggaa gagctggaaa accagataga
    56281 ttaatttatc catcaaagta ttgttttcaa tatgaagaag aaataaaatc catatatcaa
    56341 aatataacgc aggcttttgg cataaaaaat ggacctcttt atgtacaaat gttagtggga
    56401 gcatatggaa taaaggtatc tgaagtaatg ccaagattac ctggaggttg tgactatatg
    56461 gctatttctc aaataacaga tttagacata ggaagtttat ttgcaaactt tagtgtgaat
    56521 aatgaagtaa attttgatga aataaagaaa tataatatgc atctatcaaa atgtgtatat
    56581 gcattaccaa tatacataag acctggcaca ataaaaaaga taaataatat agataaaata
    56641 gaaaacttag attatgtcac tcaatttcta ttactagtaa aagaaggaga tacaatagga
    56701 ttatatgaag atgagagaca ggattgtgga agagtttatg gagtagcaaa taatgtattt
    56761 gatgcaaata taaagaagaa atgtattcat gaaatgatag aaatacttga tgaaaataat
    56821 gaaaatatga tagaaaattt ttaaataagg gagtatgata gatatgaagc taataactca
    56881 tgaacaaatt atgtcattaa acatttctca gaaacaagga tacgagtgga taaaagaatc
    56941 ctttttaaca aaaaaagatt gtcaattacc accaaaaata agcatggtag aagaagggca
    57001 tgtattttac aatgtaatgc cgtccctaaa tcataatcat aagattggtg gaataaaaat
    57061 ggttacaaga ttgccaggga gaaatccaag tttaaattca gagatatttc tatataatat
    57121 ggaagatgct aaattaaagg ctattttaga tggcaattat attacagctt ttaggactgc
    57181 tgctgttgct gccttggcta tcgatacatt tgctaaaaaa gattttaata ctattgctat
    57241 tatgggttta ggtgtaactg cttctgctat aatgaatatg ctttcatata ctcttaaaga
    57301 taaaaatata aatataaagt tacttaaata taaagaccaa gcagagtcgt ttgtaaaaaa
    57361 gtatgaaaaa aatgaacaat ttagttttga aatatgtgac acacatgaag aacttattgt
    57421 agattcagat gtagttattt ctactgtgac atatacagat gaatatttat cagaatttaa
    57481 atggtttaaa aaaggtgctt tattattacc tgtacatgtt atgggatttg gaaatgttga
    57541 ttatctattt gataaagtat atttggatga ttataatcat ttgaaacatc tagaaaatat
    57601 agatagatat aaatattctt gtgaatttta tgatgtttta agtaaacaag ctaaaggaag
    57661 agaaaatgat gatgagagaa taatatctta caatataggt ttgtcaatac atgatatatt
    57721 atttgcaaat aaaatttacg aattgtgtga aacactaagc tgtgaagaaa tagaattaaa
    57781 agaaccaaaa gaaaaatatt ggatatagtt tatttcattc atatttacaa tagtttattg
    57841 taaatatgaa tatgaagtaa tatattgtta gaaaattagc atgaatagga tagataaatt
    57901 tatggataaa tataatttaa ttaggttcgt atctattgga aacgaatata taggaaattt
    57961 agttgcatta gaatcaaata aagcaatacc ttttgatata aagagagttt attacatata
    58021 tgatgtacca aacaatgtaa agagaggatt tcatgcacac aaaaacttgg aacaagtact
    58081 agtttgccta aatggaagtg tgaagataaa atgttatgat ggtgtaaaag agactatatt
    58141 taatttacat aaaaatgatg ttggattata tataggaacg ggagtgtggc atgagatgtt
    58201 tgattttgat gaaaaaactg ttttaatttc tatagcatct gaacattata atgaagaaga
    58261 ttatattaga gactataaag aatttttaaa gtatttaaat aatatgtagt tattatacag
    58321 ttagtgatgt attttcttaa ttaaataaat ttaagatagc cacatagaga atagatagat
    58381 taggatgtga atttattgtt ggttaaattt aataatttat taaaacagtt ccaaacccat
    58441 aaagaagaat atgaacagaa gattaaggat gtaatggaaa gtggatatta tatccttgga
    58501 aatgaagtaa agcattttga agaagaattt gctaactatg taggtagcaa atattgtgtt
    58561 ggtttagcca gtggtttaga tgcactgata attgctttta gagcattagg aataagcgaa
    58621 ggtgatgaag taatcgtgca atcaaataca tatattgcta gtgttatggg aatcagtata
    58681 aatggagcaa caccagtatt tgtagaacca aatgaatatt ataatataga ttcatctaag
    58741 atagaagaaa agataaatag caaaacaaaa gctatattag tagtgcattt atatggtcaa
    58801 gcaagtaata tgaaagatat acaagaatta tgtgataagt ataacttgta tttaattgaa
    58861 gattgtgctc aatctcatgg agctaaatat gatggaaaaa tgacaggaac atttggtgat
    58921 ataggttgtt ttagttttta tccaagtaaa aatttgggtg catttggaga tgcaggagct
    58981 atagtaacta gtaatgagga aatagctgat aaagtgaaaa ttcttagaaa ctatggctca
    59041 gaaaagcgat attataataa atttgtcgga tataattcaa gattggacga aattcaggca
    59101 ggtttattaa gagtaaaact taaatatcta aatgaaattg aaattgaaaa atcaaaaatc
    59161 gtagatagat atcttaatga aattaataat cccaaagtca tacttccaaa gatagaaaat
    59221 aattgtactc atgtatggca tttatttgtt ttacaagttg aaaaacgaga tacatttatg
    59281 gaatacttaa agaaaaatgg tatagagtct ataatacatt atccgatacc accacatcta
    59341 tctgaagcat atgcttattt gggatataaa aaggggagtt ttaatatagc tgagaactat
    59401 tcagataaag ttgttagtat acctttattt atcggtatgg aagatgaaga agttagttat
    59461 ataattaaaa ttataaatga atattaaact actcataata atatcaaaaa taaatttttt
    59521 atatatcatt tatttaagtt tcgttaattg acatttttaa atattgatat attgtacaaa
    59581 taaaattgaa atatatggaa aaatatagaa ttaagatgag atttgtctta tatttttata
    59641 aattaaaaat attttcaaag agtttattat aaaattctag agtatagtgt ttataatatt
    59701 tgtaattatt ggtaactaaa tataaaatat aaaatatttg attataaaca aaaaagatat
    59761 ttaaaaaatt tgttatttat tgtatactta agttaaaact aaataggcaa atctagagaa
    59821 atctagtgac gcaaagctat agggactaag gtttatatac atgaactatg tcagccagtt
    59881 gccaaaaaga gtcctaggtg tattgtatac ctaagaaaag tctagaatga ctgccttttt
    59941 ggcagtcatt ttgttatgaa aaaatcactt tatttcagta gaaaatacct ataattaaca
    60001 tactttacca aattataaca taaaataaag aaaaattatc ttaaaaagtt actattttac
    60061 aaaaaagagc aacttttcga agaaatattt aaatacatat taaaattttt ttatattttc
    60121 atgggacttc attgaaaaaa tattagtttt cttactaaaa tgatacatta ttgtattaat
    60181 gtaatggaaa tgcgattaat ttaaatgaat aaagaagtca ttttttgtaa tatagcaact
    60241 tcattttttt attaataagc aaaataaata aaatatattt tgaggaggag tgagtgtgaa
    60301 tacatatgac attataaaaa tgggattaga tgcaactaat ttaagaagtc agacaatagc
    60361 aaataatata gcaaatataa atactgaagg atataagaga cattatgtaa cttttgaaga
    60421 aacattaaat gatgctatgc ccaaaataga agaaaaaaca gataattcta aaggattaag
    60481 agtggatggc aataatgtag atatagaaga agaaaaagta aaccaagcaa tgacaacatt
    60541 acaatataat gctttgataa gttttgcaaa tggaaaaata gcaatgacta aatcaataat
    60601 aagtgggagg taattaaaag gtgagtgtgt tcagtggaat gagaatatct gctagtggat
    60661 taacagcaga aagcttgaaa atggatatca tatcgtccaa tgtagctaat ataaatgcca
    60721 caagaggtcc aaatggagaa gcatatagga gaaaagttgt ttcatttgaa gaaaactatg
    60781 ataataaatt aggtatgcta ggagtaaaag ttacatctgt tgaagatgat aaatcacctc
    60841 ttaaaaaagt atatgaccca tctcatccag atgcaaagcc aaatggatat gtagaatatc
    60901 caaatgtaaa tatattggta gaaatgacag atttaataac agcttcacga gcatatgatt
    60961 ctaacgtaga tacattgaat gctcagaagt ctatgatatc aaaagctttg gaaataggaa
    61021 agtagggata aattatgcca attacacaaa ttaacaattt aatgcaaggt gcaaagttag
    61081 ataatttgat tggagaaaca aaaccattaa ctcttaataa agaagaaaaa aagaattttg
    61141 aagatgtaat aatagatact atagataaag ttaattttca acaagtgaca gcagatgata
    61201 tgaaagaaaa atttataaaa ggcgaagatg tttctatgca tgaagttatg ttaataggtc
    61261 aagaagcaca gctatctatg caatatttaa tagaagttag aaataagatt catgatgcat
    61321 atcaagaaat gaataaggta caaatttagc cttttgaaca ggagtaataa tcaatgatag
    61381 ccagttttaa aaataagatt aaagagcaag ttgctaaatc taggacaaag ataagttctc
    61441 taaaaaaggg aactaaaata gcattaggta taggggttat tgctatatgt ttagcgctag
    61501 tatttacagc aatatctgcg agcaaaaata agtatgcagt cttattttca gaactagatg
    61561 ttcaagatgc tgcagatata tcagcagaat tagagtctaa aaagatagat actaaggtaa
    61621 agggaagtac gatttatgta cctagaacag aagttgataa gttaaggctg gagttagcac
    61681 caagtcttac aagtggttct aaaggatttg cactaatgga tgatagttca tcaataggac
    61741 ttactgatga agagtttcag attaagaagc aaagaatgat acaaggtgaa atagaaaaaa
    61801 caataaagag ttttccacaa gtggaagaca ctagagtaca tataacattt ggagagtcat
    61861 cagtatttga gaaggaggct gttccaggga gtgcagcagt ttatttgatg ctaaaaccag
    61921 ggacgacttt agaaaaaaac caaataaagt ctgttatggc acttatatca ggaagcgtta
    61981 caaatatacc agagaaaaat gttcaggtta ttgataacaa aatgaattta ttatctgaag
    62041 gtattttgga ggatgaaaat gttaatgaaa ataatcaacc aataaatagt ggcattagtg
    62101 ttgataaaaa taaggcatct gaacaagcat tgaataaaca actagaaaag tctattttag
    62161 aaatactaga accaatattt ggtaagggaa aggtgaaagc tacagtaaat gctgatttaa
    62221 gttttgatac agctgaaaaa actgagataa aaattgaccc tgataaagtt gcaataaaag
    62281 agacaaggtc gaaaaattca tctaaatctg ctacaaataa tgttcaaggt gtagatgcta
    62341 acatgaataa ccaaggaaat aacaatggta ctaatacaga agatagttta gatgagagtt
    62401 ttgagtatga aacaggtaag attgaaactc atactatagt tgcgcctgga gaacttaata
    62461 gattgacagc ttctgttgca atagatggaa aaatagctaa aggtgttcaa gctgatgtag
    62521 aggatattgt taataatgct ataggtatgg atggagcgag gggagatact cttagcgttg
    62581 tttcaatggt atttgaccca gaaggtaaga aagaggctaa acaagagctg gaagagatta
    62641 aaaaagaagg atttaaaaag aacataataa aagcagttat tggagtagtg gcagtagtag
    62701 caattggagc tattggatac ttgatatata agaaaagaag tgaacgagaa gatatggatt
    62761 atgaagatga agattatatt tctaaatctg attctgttga tagaaaagat aatcctctat
    62821 taggagatga cccagaactg acattagagg aagctgttaa aatgtatgca gaagaaaagc
    62881 cagaccaagt aacagagata ataaaaactt ggttaaatga gtaaggggga tagaaagtgt
    62941 ccacggaaat tacaaatgtt aatgcgtttg acttaagtga tataaatgag agtgataaga
    63001 aagagaagat agaaggtgag ggtttaaaaa aagctgctgt attattaatg acattaggac
    63061 caaatgtttc tagtgatata ataaaaagct tgcctgataa acaagttcaa aaaataggtt
    63121 tggaaattgc aaatatttct tcaatagctt caaaagaaag aagagaaatc ttaaaagagt
    63181 ttgtagaaat aaatagggca aaagattatg ttatagaagg tgggcttgaa tatgcaagag
    63241 agttgttaag caatgcttta ggaaatgcca aagcaaacaa attacttgaa ggtatatcaa
    63301 taaatacaag cacaaagcct tttaaacata ttataaaact agatgtaaag aaaatattag
    63361 aaatacttag gaatgaaagt gcacaaacta tagccgtttt acttgcacat atggagccag
    63421 aaaatggagc agaagtttta tcatacttag attttgattt acaaaatgaa gtagctatga
    63481 ggataagctc aatgggttca atatctccag aagtaataaa agtaattgaa agttcattag
    63541 aagataaatt acactcaatg agtggtgatg attttaagga ttatggagga gtgtctacct
    63601 tagttcaaat attgattaat tctgatagaa aaacagaaaa gaatattttg ggaactattg
    63661 aagaacaaga cccggattta gcagctcaaa ttaaatctca tatatttgtc tttgaagata
    63721 ttgtcaagtt agatgatata agtatacaaa aagtgttaaa agaagtgact atgaaagatt
    63781 tagtatatgc cttaaaaggt gtggatgatg agatttcaga tgctatatat agaaatcaat
    63841 cttctagggc agcagaggca cttagagaag aaatggaaat ggttggtgtc ataaaagtta
    63901 cacaggttga ggctgctcaa caaaagatag caaatatagt aagaaaactt gaaagagaag
    63961 gtgccataac tattgtaagg aattttggtg gtgactttgt tgaataataa gattattaaa
    64021 agtaaaaaag cattatataa aggagtgcta gatttaacca taatagataa agttagagtg
    64081 ggagaatcaa atgtaaataa agaaaatgat tgtagattta gggatgaggt aataaaagaa
    64141 gctatagaat ctgctgagat aaaaaagaat gagatattag aagaagcaaa aatgaatgca
    64201 caaaatatag aaaagcaagc atatgaaaaa gggtatagtc aaggtcaaaa aaatggatat
    64261 gaagatggat ataaagagtc atataatgaa tatacccaaa aagctaaaga tgaagcagat
    64321 tttataaaaa atcaggcaga cttaatacta ttacaagcta atgagaagat gactgagtac
    64381 ataaaagaaa aaaataaaga gattgtaaga cttgctatta atatggctag ttctgttcta
    64441 aaaaagcatt tcgaagatga agaatctatg agtgatttgt taaagcaaat tattcaagat
    64501 tatgaaggaa gtagttcatt tatagtaaga tgtaattctt tctataaaga taatatagag
    64561 aaagagtttg aattattcaa agaagaaaca tcactaaaat caagtgtatt tgttattgca
    64621 gatgatagta tagataaagg caatgctatc atccaaaagg aaaatggaag aataatagtt
    64681 ggtatcgatt gtgctatgga aaaactaaaa gaagaattgc ttggtgaata aagtatgtat
    64741 aaaactgata tatctataga ttttgacaaa ataaataaga aaatagaaaa tttagaactc
    64801 actatatcag aaggtagagt caaaaagata ataggactta ctgtagaagt tgaaggaata
    64861 aaagcttttg ttggagagtt atgtgttata tacaatcaag tcaataaacc agtgaattgt
    64921 gaagtagtgg gttttaaaga taaagaagtc atattaatgg cgttgggaga gttaacattg
    64981 atagctcctg gttgtaaagt tatttctaag gggatacctt taagtgttat gtgtagcgat
    65041 aatttactag gcaaagtact tgatggtctt ggaaatccta tagataactc agatgctgtt
    65101 ttaggagata gatacaactt gaacaatgaa cctcctgatc caatgaagag aaaaaagata
    65161 cgaaatataa tggaaacagg tgtaagagca atagatgcat ttactacttg tggtgaagga
    65221 cagagaatag ggatatttgc aggaagtgga gtaggtaaaa gtacgactct aggtatgatt
    65281 gctaggaatg caaaagcaga tgtaaatgta attgccctta ttggagaaag aggaagagaa
    65341 gtattagatt ttattgataa agatttaggt gaagagggaa tgaaaaaatc tgttgttgta
    65401 tatgcaacat cagataaagc tcctttggtt aggctaaaag gtgctcttac tgctactgca
    65461 atagcagagt attttagaga ccagggcaaa aaagtaatac ttatgatgga ctcggtaact
    65521 agatttgcta tggcacaaag agaagttggt gtagcaatag gagagccacc agctcaaaaa
    65581 ggatatacac catctgtgtt tgctatttta ccaaaactta tggagagaac agggacatca
    65641 gataaaggtt ctataactgc attttataca gtattagttg atggagatga ctttaatgag
    65701 ccaatagcag atacaacaag agggatactt gatggtcata tagttttatc tagagacttg
    65761 gcaaataaga atcattatcc ttctatagat gtattgaaca gtttaagcag acttatgaat
    65821 gagattgctt caaaagaaga cataaaaata gcatcttttg cgagagatat gcttgctgag
    65881 tatagagaag cagaagattt gataaatata ggtgcatatg cttcaggtac aaacaaaaaa
    65941 atagatgaag caatctacta tcatgagcat attattaatt ttttaaaaca aggaataaat
    66001 gaaaagagct cttttaatga aactataagt agtttaagag gaatctttga ataaacaatt
    66061 taaaaaaata tttgaatagg ttgtgatgga attggataaa aattttaagt ttagattaca
    66121 gaaagtttta gacttaaaaa taaaagatga agaagagata aaaatggaat ttgctaagat
    66181 tcaacaaaaa aaaatagata tagaaactaa tttagaaaac ttagaaagta attacagcaa
    66241 atattctata ggtaaaaata atgatagtgt tcaaaatcaa aaaataacta ttaactattt
    66301 gctagcttta aacaactcta taatggattt atcagaaaaa ctggataagt cgacaaatga
    66361 acttgaaaaa gctagaaaac agcttataag caaacagata gagagaaagt cattagaaaa
    66421 attaaaagaa aaaaaatatg gacagtatta taaagaagaa cagttaaaag aacaaagcac
    66481 taatgatgag tttgcaagca tgagttattt gagaaataga caagttctat aaaatagtag
    66541 gaagtgagga tattattgta tgaagataca agcagattct tataatatta ttaaagatat
    66601 tgggaataga aaaaactcat ctaagaataa aaatataaaa aatgataaat ttgaagataa
    66661 tctatataag acaacagacc ataaaaaggt taaagataga agagaaacaa gtaagcaaaa
    66721 tgttagctca gatagaccgg aaaatagtga taatgagtgt catttagatg aagataaaag
    66781 taatcactta gaagatgaaa atacatatga aaaagattgt agtaataata atgaagcttt
    66841 gcagcaatta ctgaatcttt taaaagagaa ttataaaaaa gataaagata taaacactat
    66901 attgaataat ataaaaaaac taagtatatc agatgaatta aaacaagaac ttaagcttaa
    66961 taaaaatata ttaaataaga ttgcaaatca aaattcagag ctaaataaag ctaatataaa
    67021 taactctaat gatatagaaa atttagacat agttaaatta agagaacttt tggaggataa
    67081 tgctaataaa gatattgaag taattactaa aactacagaa aatgatacta aaaatataga
    67141 tttgtatagt tttgatagca atagaatgga taatcttaac tcaaataaac agaaagatga
    67201 tagctctgat attttggaaa aactagcagg ggtaaatgga aataagagtg ggaattttgg
    67261 acaagtaata aataaaaatg ttgatatgaa taaaattaaa aatgataatg tcaatttaaa
    67321 acagatagaa tcaaatgtaa tggatgactc tataaaagct attaagcata tgaaaacaaa
    67381 tgatatacaa gaattgacaa ttaaattaag accaaaagaa ttaggagata tgaatataca
    67441 attgttaaaa gatggtgaaa gtatgagagc tgttgtgact gttttcaata aagatgtctt
    67501 tgactctata aataaaaaca tagcagattt aaagcaacat cttgaactta ctaatgtaaa
    67561 tataaaagat gtatcagtgc aaatgcacag cgataataca aatacatctg atacctttga
    67621 taaagcattt gaacaacaga atagacaaaa taaccaagaa aacatgagta agaagaatac
    67681 aaatgataag cataataatg tagtcataga agatgacatt aaagaaaata ctattgatga
    67741 tgatagagta gatttactag cttagtaagg gggaagtatt gcatgtacgg aatagcaacg
    67801 gctttggcag gaactcaggg aaactatagg tcaaataact taagccaact tgaaagaaat
    67861 attaatgata ttgccaataa acaagttaga agcaaaggaa atcagacagt aacagacaat
    67921 gggactccaa ttataggaca aggtgatgat gctgataaag acttgtttat gaagatactt
    67981 gtggcacaga tgggtaatca agacccaatg aatccgcaag acccaacaga atatgtgtca
    68041 caattagcac agtttgcaac tttagaaaag atgtcagcta tgaatgagaa gctagatgta
    68101 cttttagcct taagtaattc cactctaata aactctgctt taagtatggc aacatcatta
    68161 attggtaaag aagtagaagt atctggggaa gagaaagaag atgaaaacat tgtaggagta
    68221 gtaaagtcca catatataaa agatggggaa gtacacttag aattagaagt agatggaagt
    68281 gacaaaactg taggtgttaa atatgaaaaa ttacttaaaa taggagaggt agatgaaaat
    68341 tcaggagaag aaaatgattc ttcagaacac gaatctccag aagaagcata atattaaatg
    68401 agaaaagagg taaattcatg ataaaagcaa tgtattcagg tgtaagtgga atgaaagcaa
    68461 atcaaacaaa attagatgta ataggtaaca atgtagccaa cgctggaact acttctttta
    68521 agaaaagttc agctagaata acagattcat tttatcaaac tgtactatat gcaagtgctc
    68581 caacagctgc attaggagga acaaacttag gacaagtagg tgtaggtagt aagatatcaa
    68641 gtataaataa agatatggta caaggaaatg tacaaccaac taatagacca tctgatttaa
    68701 tgatagatgg agatggatat cttccagtag taagacaagg aacagttatg tatacgagag
    68761 atggttcttt taatttagat acaggattta aagcagctga tggtgctttg aagaatatta
    68821 aaggtggaag acttgtaaat ggtgatggat atatgttaca aggtatgatt tatgatgggg
    68881 aatataaagc tgatactgga gaatttgtta aaaagggtga tgctaaagga aaagagccta
    68941 ttgtaatacc acttcaaagt ataagtccta aggatggaac agttcaaaat gtactagagt
    69001 ataatatatc aaaggatgga acagtagaat ttttattgag tgatggtcaa agaactcaat
    69061 ttgtctatga tatacctgat ggtgctaagg taggagatac acctgctgga atagataaat
    69121 taaaaggtac aatacaaaaa gtgcaaacat atgcattcca aaatccagca ggactagatg
    69181 cagaaggagg aaacttgttt aaaccatcag caaactcagg agacccacaa atagcaggag
    69241 ctacaggcac aataatacaa ggggcaatag aagcttccaa tgtagatata gcagaagaat
    69301 ttacagaaat gataatagca agtaggtctt tccaagcaaa cagtaaaata atatcgacat
    69361 cagacgagat acttcaagaa ataataaatc ttaagagata gtaggtacat attatgataa
    69421 gagtaacgga tttaaacgga agaaaataca tattaaattc agaccttata gtgaggattg
    69481 attctgtacc agaaagtagg attctcctta caacaggaga aaaaaacctt gtaaaagagt
    69541 cggtagatga gatagtagat aaagtaataa agtataaaag aaaaataaat gtaggttata
    69601 ttaggagcga aaaataatga aaaaaacaga ttcactgaca tttattggac taatagtatc
    69661 tacagtatta gttttagttg gtgccgcaaa aggaagtagt tcagggttaa agaatttttt
    69721 tgatgtttca tcaatattaa tcacagtgct tggttcattt ggagctctaa tgattacatt
    69781 tactatagat gatataaaac ttataaaaaa tgcattacaa tactcattta agacaatgag
    69841 tgtatcaaag ttagatttac tagaacaatt taaaacactt tctaaaaaag ctagaaaaga
    69901 aggtctttta tcaatagaga gtgatgtaat gggaatagaa gatccattta tgaagaaagg
    69961 gttagagctg tgtattgatg gattggaaat caatgagata aggtccatct tagaactaga
    70021 gatagattct gttgaagata caaataacag atactctaaa ctatttaaaa cttggggaac
    70081 ctttgcacct gcttttggga tgttgggaac actaataggt ttaatacaaa tgttagctga
    70141 ccttacatct ccagatttaa tagcatctgg catgggaaag gcattaatta caacgtttta
    70201 tggttcttta cttgccaata tcgctttgaa cccaattgca tataatatag atgagaagac
    70261 tgaaaaagaa atttatgtaa aggaaatgat gttggaaggt ataataagca tacaatctgg
    70321 ggagagcagt atagtagttg aggaacgttt agccacatac ctttcaaaca atgagaagtt
    70381 agaaattatg aaatccaata aaaatacaga aagagcaatg agcaatggcg cgtaaaaaaa
    70441 ataagaaaaa ggatgagata aatccagatg catggctggc tacttatgca gatactataa
    70501 cactgattct tacatttttc gtattattgt atgcaacatc agttgtagat atggaaaaat
    70561 ttaaaaacat agcagatgcg ttaaaaggtc agttttctgg gacaagtata tttagtacgg
    70621 gttcaagtac aagtgagaaa tctccaatag acagtgtttt agtggataaa aatgataaat
    70681 caaatttaga acaggattta aaagataaag ttaataattc taacttacaa aatagtgtaa
    70741 cagtcaaaga tgatagtaga gggattttac tagagttaga tgattcaatt ttatttgact
    70801 ctgggatttc tgagttaaaa gtagatagta aagctactct taataaagta tatgacatga
    70861 taaagatgat gaaaaataag atagttatag aaggccatac tgataatgta cctgtaaaat
    70921 caagtacaca tgaatccaat tgggatttat cttctagtag agcagtaagt gttgtaagat
    70981 actttgtaga agaaaagggc atggacccta gactattttc ggcaacagga tgtggagagt
    71041 atcaaccttt ggtttcaaat gaaacagcaa agggaagggc tgagaataga agagttaata
    71101 tacttataac tattgactag gaggaagagg tttgttcaaa aataaaaaaa ttattataat
    71161 tattttgata ctgattattt tctcagcggg agcaggtttt tttatattag gagaaggtgg
    71221 aaataaacaa gttgacaaga ttgcaggttt gtttattcca acaggaaaag gtaaagatga
    71281 agtaaagacc gaaaatcttg acttagaaga gatggtatta aagttagctg atgaaggtgt
    71341 aagatattta aaagtatcaa taactgtatc ttatgattct tcatataaag atatagaaaa
    71401 aaatacgcct ttaattaggg ataatattat aaattgtttt atggcaaaaa gggcagatga
    71461 ttttactgct gataatttaa agaacataaa agaagaaatt aaaaatacat taaatataca
    71521 actaggtgaa aatgtaattc aaaatatata tttcacaaat atagtagtgc aataaaagga
    71581 tggtaagaca tgatacttta tttactaaaa atattaatat gtatcccaat aattttaata
    71641 ttgatagtct tatctttaaa aattagccaa ggaactttat taaaaaaata taatgataaa
    71701 tatgtaaaaa tactagatat tgtaaatata agtaaaaaca atagcataat aattttaaaa
    71761 ataggtgaag aaggatgcat tatggcatct tcttcttcta gcatgagtaa aataaaagat
    71821 ttgaccaaag aagaagtatt aaaaatagaa aacgacatta aagaaagaaa ttttaaaatt
    71881 caagatttta aaatggaaag aattaaaaag aaatatgatt tcagtagata tattggaaaa
    71941 tttacaaaaa aggaagataa gtaaatggaa ctattatcaa aattaccttt ggctgatgta
    72001 ccatatacaa gttcaatgca attgttttta tttctaactg cattaatgtt tttaccattt
    72061 gtaatgttca tgatgacaag ctttgtcaga atagttataa gtttatcatt tttgaaatca
    72121 gcattaggag cacagcaagc aattccaagt caaattttgg taggacttgc aatagtattg
    72181 acaatattta taatgagacc agtattaaat gagataaacg aaaaggcatt acaaccatat
    72241 atgaaagaag aagttactat ggaagaagct atgaaggaag cagaaggacc tattaaagag
    72301 tttttattaa cacaaaccag acagacagat ttagatttat ttgtagaaca ggctggttta
    72361 aaagaaaaga aattaactcg tgaaaatata ccactatctg ttgtagttcc agcatttgct
    72421 ataagcgaac taaaaactgc ttttcaaata ggttttttaa tatatatacc atttttgata
    72481 atagaccttg ttgtggcaag tgttttgatg tctatgggta tgtttatgtt gcctccagtc
    72541 atgatatcat taccatttaa gttattatta tttgtaatgg tggatggatg gaacttgata
    72601 gtaaaaacat tgatattggg atttggatag gagaaaaata gtatgagtga atttatgata
    72661 atgagtgttc ttaaaaatgg catgtttaca ggagctatga ttgcagctcc agtactcatt
    72721 gtttctcttg tagttgggct tttaataagt gtgtttcaag ctacaactca aatccaggag
    72781 caaacattga cttttgtacc aaaactaata gctattcttt tagtagtagc tatcggtgga
    72841 agctggatgt tacatactct tattagtttt acttctgaga tattcaatat gatatctctt
    72901 ataactaaat aagtaggata catatgattt ttgtatttat tagaatagta gcattctttg
    72961 gaacactaag aatactattt ccagctggta cacctgcttt atttaagtca ctctttgcaa
    73021 tcattatatc aatattgatt tcaagtacta tgcaaattga atatgcaaca aatatagaca
    73081 acattgtatt gtttacctta tatagtgtaa atgagaccat aactgggatt atgcttggat
    73141 atataaccaa cctatgtttt tatagtatca gaatggcggg ttctatgatg gaccaacaga
    73201 tgggattatc aatgattaat atgtttgacc caaattcaat gactcagaca actttaattg
    73261 ataatcttat gaactggaca gcacttatga tattttttaa catggatggt catcatgttt
    73321 taattagagg tataaggtat agttttgagt taattccaat aggaaaacca tttgtagata
    73381 ataacataga ttatataata aacatatttg tgcagtgctt tttaactgga ttcaaaatag
    73441 caatacctat tgtactttgt ctgcttatgg cagattttat tttagggctt atatcaagaa
    73501 gtgtacctca attaaatgta atgatagttg gtatgccatt aaaaatattg gttggtattg
    73561 cattatttat catatcaata cctttaattg tcaatcaaat aagtcattta ttaagtcaaa
    73621 taccaaagat gtatgaggga acttttgcac tagctcctat gttttttatg ggttcagcag
    73681 ataaaacaga agaagctact ccaaagaaaa agggagaaca aagaaagaaa ggtaatatag
    73741 caaagagtag agaattaccc gttgcaatga ctctacttgc attcacctta ttagtaccta
    73801 cattattttc atatgtagta gatacactta aatcttcgct taattatttt ttgagtctag
    73861 atttttatat gaacataaat tattcaaacc tagagaaatt agttatagca ggattaatgg
    73921 atttttttaa gatattttta ccaatagcta ttcccttttt agttttaggc ataatagcaa
    73981 acctatttca ggtgggaata ctgtttactg gtgaaacttt aaaaccaaat ttatcaaaat
    74041 taaatccaat tagtggattc aaaaacatgt tttctatgag aagtttgtca accttaataa
    74101 aggatacagc gattatatct attttggctt acataggata tacattcttc caagataatt
    74161 atttagatat attaaagtta ggtaacatat acctaccaac tttaatgtac acagttaaag
    74221 acttagtata ttcaatattg agtaagattt gtgtagctat gatagctata gcagttgcag
    74281 attatgttta tcaaagatac agtcataaaa agcaactgag aatgacaaaa caagaagtta
    74341 aagatgaata taaaaactca gaaggagacc cagaagtaaa agctaagata aaacaaaaac
    74401 aaagacaaat ttcgtctcaa aggacaatgc aagcagtacc aagtgctact gtaatagtaa
    74461 ccaatccaac ccacttatct atagcagtga gatatgaaaa agggaaagac caagctccag
    74521 tagtggtggc aaaaggtgca gattatttag cttttaaaat aagggaaatt gcaaagggaa
    74581 atgacatacc tataatagaa aataaaccta ttgctaggtt gttatataag caagtagaaa
    74641 tagaccaaga aattccagag gacatgtatc aagcttttgc agagatatta gtagcagtat
    74701 ataaaatcaa aaatagatac aaagtcccca aaaggtagga taagtaatga ataagtttaa
    74761 tttaaaggaa aatatggacg taatagtggc atttggtgtt gtagggattg ttcttatgat
    74821 gatagtgccg ttacctacat ttatattaga tattttactg gcaattaaca taagtttatc
    74881 tgtgctaatt ttactaatga cactatttac aacaaatgta cttgatttat ctatatttcc
    74941 aacagtgtta cttgtgacaa cactatttag attgggatta aatctttcat caactagatt
    75001 gattttaaca cagggatatg caggtgaagt tatagaggca tttggaagtt ttgttgtagg
    75061 tggaaattac gtagtaggaa taattatatt cttaattata ttaattgttc aatttgttgt
    75121 tataaccaat ggttctggaa gagtatctga agtaacagct agatttacgt tagatgccat
    75181 gccaggtaag cagatgagta tagatgcaga tttaaatgca ggagttatag atgacaaaac
    75241 tgctagaaaa agaagaaaag agcttcagca agaagcagat ttttatggct ctatggatgg
    75301 agcaaataag tttgtaaagg gagatgccat agcaggtctt atagtaacag caataaacat
    75361 aataggtgga attgtaatag gagctgtaat gctgaatatg actcttatgg gtgcagcaca
    75421 gacatatgta agacttacta taggggatgg tcttgtaagc cagatacctg ctctattaat
    75481 atctacatca gcaggtataa tcgtaacaag agcttctact gatgaaaact ttggtggatt
    75541 agtaggtaaa cagttaacag caataccaaa agcagtaatg atgactggct gtgttctaat
    75601 cgtacttggt atgatgcctg gattacctaa accagcattt ttttcactag gtataggtgc
    75661 tatagcagca ggttactttt taggaagaga aaagaaagat actttagaag acttggagtt
    75721 tgaaaaacct gatatggtaa atccagataa aaatgaagta gaagatgtaa caaacttaat
    75781 aaatgtagaa tcaatagaag tagaaattgg atatggttta atatctttag ctgatgaatc
    75841 agcaggagga gatttacttc agagaatagc atcaataaga agacaatgtg caatagacat
    75901 gggtatagtc gtacaaccta taagaataag agataattta cagttaaatc caaaccaata
    75961 caatataaaa ataaaaggga atgtagttgg tgggtatgag ataatgccta atatggtttt
    76021 atgtatggat cctatgaatc aaggatttag tatatttgga ataaagacaa ttgagcctac
    76081 ttttggaata gaggcacttt ggatagaaag tgacaaggta gaagatgcag agctaaaggg
    76141 ttatacagtt gtagattcat ccacaatact tataactcac ttactagata taataaaatc
    76201 aaatgcacac gaattactgg gaagacaaga agttaagact attatagatg cagcaagaga
    76261 aaattatagt gctgtagtag atgaattgat accagattta atgacacttg gtgaaattca
    76321 aaaagtactt aaaaatctgt taagagaaaa agtaaatata aaggatagag ttacaatact
    76381 tgagacactt gcagaccagt ctagaaatac aaaagatata gagcttctta ctgaatatgt
    76441 aagaatagct ttggctagaa gtatttgtaa taatttagtt gatgaagata aggcaattgt
    76501 agtggctaca ttgtctccag aaactgaaga attggtatct aataatttac aaaggtctgt
    76561 aaatggaact tatccagcag ttgacccaga aaatacaaat aaaatatttg agagtataca
    76621 agaagtaatg aacaatgtat atttcaatca taatatacca gtaatagtag tatcaccaaa
    76681 gataagagct ccatttagaa aattagttga aattgtatat cctaatttga ctgtattatc
    76741 attaaatgaa atacctaacg atattaaaat caaagcagaa ggtgtggtga gcatatatga
    76801 tgacgaaaaa gtatacagct aacacaattc aagatgctat gaatctagcc aaaatggaat
    76861 tgggtgacaa tattacatta atagataaaa aagaggtaag aaaatctgga ataagaggca
    76921 ttttttcaaa gaaagatatt gaattgacta ttggatggga aaagaaagat aatttagaac
    76981 aaaaagattt aaaacgagag atagaacaac taaagtcaat tataaataat atggggtttg
    77041 ataataaaaa tgataatgat atagataaaa tatgcaagaa tttactaaac ttagatttaa
    77101 atcaagaaat tgtagaattt ataaaagctg atttacaaga aatgaagttc aatggaattg
    77161 atacaagtaa aaatttagta gaaagtctaa agaaaaagat taaaatagaa aatcaagcaa
    77221 taaatggtaa aattgcttta gttggaccac caggagtagg taaaacgact acaatagcaa
    77281 agttggctgc caaattagtt tttgaggaaa ataaaaaagt aggagtaata actatagata
    77341 catacaggat tggtgctgta gaacagttaa agatatatac tgatataatg aatattcctt
    77401 ttaaaggggt aataagccct gatgagatgg aattggcact tgatgcgatg aaagattgtg
    77461 atgttgtatt aatagataca acaggtagag gctataaaaa ctctatgcaa atattagaaa
    77521 tcaaaaatct tatagataaa gctgaaactg ataatataca tttagttttg aactgtacaa
    77581 caagagaaag tgatacaaaa gcaattatag attcatatag aaatgtgaat tttaaaagct
    77641 taataattac aaagttagat gaaacaataa catatggctc aatatttaac ataatgaatt
    77701 atgcacaaaa accaatatca tatattacaa caggacaaaa tgttcctgat gatattataa
    77761 aacctaatga agataagatt ataagattac tattaggagt tgaaagtata tgatagacca
    77821 agctcaaatt ttgagaaaaa tggcaatgga aaaaagaggt tctgatgaga ttatagtaga
    77881 gaatgagaat atgcctaaga taattacaat agcttctggt aaaggcggcg ttggaaagag
    77941 taatctcgct acaaatttgt ctatatgctt aaccaaactt gataaaaaag ttcttatatt
    78001 agatgcagat ataggaatgt ctaatataga tataataatg ggggtaaatg taaaagggac
    78061 tataattgat gtaattaatg gcgaaaaaaa tatagaagat ataatttcac agactaagta
    78121 tggtgtaaat gtaatatctg gaggttctgc ccttaatcat atagaagact ttacagaagc
    78181 tcaaagaaat aagtttatac atagcataga acagattcac aatgtggatt ttataataat
    78241 tgatacagga gctggtatga gcaaaagcct attgtcattt atatactgta gtactgaatt
    78301 tttcttaata acaactccag aaccgacatc attgactgac gcatatagtt tattaaaagc
    78361 tataagtaat tttggcataa agaaaagtgc aaatataata atcaataggg taattgattt
    78421 agaagaagcg aaatctacat acaaaagaat aaaaatggtt gtggacaaat ttctaaacct
    78481 taatctggaa ttgtatggat atataataga tgacaaaaaa gtaagtttat gtgtaaaaaa
    78541 acagatacca ttcattttag aatatcctac aagtattgca tcaaaatgta ttatagccat
    78601 agcaaagaga atggtaagtc agtcaagaga agatattgtt gataataaaa gttttctaag
    78661 aaagatgttt agtatattta aaagctaagg aggcgtagtt aatgaataga gaagaattaa
    78721 taaaagagaa tatgcctctt gtaaagagta tagcaagaaa attttttata ccagggaaag
    78781 gttttgaata tcaagactta gtaaatagtg gagtcattgg attgattgat gcaataaata
    78841 aatttgatgc tgaaaaaggg gcaaagtttt ctagttactc ttatataaaa ataaaatctg
    78901 ctatattaga tgaaattaga aatcaaagtc caatttctaa acataatcta actaaagtaa
    78961 ataagtataa tagagtggta gaaaagttgc aatctaaatt attaagagag ccaacttcat
    79021 atgaaattgc aaaagaatta aaggtttcag aaaaagaact tcatgatatc gaaagtaata
    79081 tagatatgtt aaatattgta tcattaaact atgtaatctt tgaagataca aatgaaactg
    79141 tacaagatgt aataagtgat agagaagagg aagctccaga aaatataata gaagaagaag
    79201 aaaagttaga gattctatcc aaagcaatta gtaatttaaa tgaaagagaa aaattaatac
    79261 tttcactgta ctattatgaa gatttaaatc taaaggagat agggaaagtg ctaggtgttt
    79321 cagaatcaag agtttcacaa ctccacagaa aatcaataag aaacttaaga aacaagataa
    79381 aagaacttaa atattctata tagatggtga ttgataagat gatacaaatt atattaatag
    79441 tagtgtctat tttaataata gtaactatag ttataaattt acataaggaa tcaaaaaata
    79501 aagataacag atactttgat aaaatatttg agcaagaata tgaagcaaat gatagattaa
    79561 taattgcaga aaaaagaaga ttctttttag acaaagtact tgctgaaata agaagtaata
    79621 atcatataaa agtttatgaa aattataacc taataaaggc taatgaagaa agaaaggaaa
    79681 acatatttat agaatcaaaa aaggaagtaa gacaagaaaa tgagttatct cttaaagtga
    79741 aacatcttat aagttcaggt tatgatgatg tggaaatatg taagatgcta gatattggaa
    79801 agggggaact gtcattaata aggagttgtt acaaaatata aggatattat tatgtgataa
    79861 aaaagtattc ttaggaatag gtattggtat attaatatca actttatgta taatgctttt
    79921 tagtaataat gatatgagta aggcagagat agaaaaaaag gccagagcgt taggcatgaa
    79981 atatacaagt gagatgaaag tcttagaata gatgatactg tttagacatt tacaaaaaag
    80041 gaggtcataa tgtgataaga ggattatata cagcagtttc tgctatgata actaatcaac
    80101 aaaagcaaaa tgttgttgtc aataacctag ctaatatgga tacaaatgga tataaaagta
    80161 aacaactttt gactaaaagt tttgatgaat taaagttgga gggttacaat aactacgcaa
    80221 atggaactaa acaaaagcag attataggcg atataagtcc aggtatttct atggatgaaa
    80281 ctatcacaaa ttttaatcaa ggacctataa aaactactga taataaaatg gatgtagcta
    80341 ttcaaggtaa gggatttttt ctagttagtg atgcagctgg aaatcaattt tacactagaa
    80401 atgggaactt cagaacagac aatcaaggtg accttataac aagtgaaggg tattatgtac
    80461 ttgggacgaa tactgctact ggtgctgtag gtcatataaa tgtaggaaat caaaaatttg
    80521 aagtggcaaa agataataca atatcactag acggaaatgc tatgtataaa tttaatattg
    80581 tagattttaa taactacaat aacttaaaaa aagaaggaga taacttatat tctggaggag
    80641 gagctatgaa agtaaataat gcacttacaa tacaaagtgc gatagagtcc tctaatgtag
    80701 atatggtatc tgaaattaat aatatgatga caatatcaag agaatatgag gcaaatcaaa
    80761 agataattca ggctatggat tctaaattag caaaaatagc aagtgagatt ggttcagtaa
    80821 gataggtaat aggaggtgaa tttttatgta cacaatgttt tatactagta aaacagcttt
    80881 atcagcaaat caaagtaaac tagatataat atctaacaat atagcaaatt ctgattcaac
    80941 aggatataaa aaaataaata tggaatattc tgatttagtg gatgaagtac taaatagacc
    81001 atcatatcct acaaatggca atgatatatc gactggaaca ggagctaagg caacagctcc
    81061 catgagaaat tatgaacaag gtgcattggc tcctacagat agtaagagta atttggcaat
    81121 agatggagaa ggattcttta gagtgataag aaaagatggt acatatgcat atacaagaaa
    81181 tggtggattt aatgtagatg ctttaggtaa gattgtagat gataatggaa atatattaga
    81241 tgtccaattt gatgcaggat ataactataa taatacaaat atagatagta caaacctgac
    81301 agtttcaaga aatggagagc tattcgtaga taataaaaaa ataggaaaaa tcaacttata
    81361 tcaacctata ggaactcaaa attttatatc tgaaggagat agtttattcg tcgcaactga
    81421 tgcagcacag attaaacaag ttgagaaagt cgatatagtt caaggctata gagagaggtc
    81481 aaatgtttct ttacaagaag aatttgttga cttaatagcc actcaaagag catttcaaat
    81541 gaactcaaag ggaataaaga cagcagatga aatgtggcaa atagcgaata atttaagagc
    81601 taaataatta tgtaaggtga ggaatattca tgaatgatat gaaagagtac gattttggca
    81661 aacctcagag ttattcaaga gaaaatttaa cttgtttaaa ttttttatta gctgaatttt
    81721 gtaaaaaata taaaaactat ataatttatg aacttaagtg taattctagt atggttgttg
    81781 atagtataga ccaagtaaat tatcagactt ttttagatag agtaacttct tcgtgcgtag
    81841 tagtacaaaa tgcaatggaa cctgttatga aaaacttttc ttttagaata gatagaagtg
    81901 tagctgatat gtggattgat ataacttctg gaggaactgg agttgtaaag gataatgata
    81961 gagagcttac agaacttgat aaaaaagtgc ttttacacct tatggatgat ttagtaagaa
    82021 atatgcactt atttgagggt tttgaaaata tacaagtatt ggatacacat acacatatta
    82081 atttaccaca attatgttct ccaactgcac cagtatgcgt tgtagattta aaagtgctaa
    82141 atgataatga gtatattgga agtgtttctc tttgttttcc atacaatggt ttagaagctc
    82201 tgttagaaag tatatctgtt atagaatttt ttgataatga tataggagat gattcagagg
    82261 aatttaccaa aaaaatatat aatagtgtat ctaatataga attatcggtt attgcagaga
    82321 taggaaaagt atcaattaat gttgaagact tacttaaact agaagttgga gatgtaatag
    82381 taacaaataa aaaaataaat gattatatag atatatttgt agaaaattca aaatcatata
    82441 cagcaacacc aggatttata tcaagtaaaa aaggtgtaaa aataaatgat gctgttggaa
    82501 aagaggtgta gttatggaca atagtaatct tatttcagat gaagaagcaa agatgctatt
    82561 aaatgataaa gttgaaagtg aagttgatgg agatgatgag ttagccttag atgtgtctga
    82621 agttaatcga aataatatac aaaggatact tgaccttaag ttagaattat ctgtggttat
    82681 aggaagaact aagatgactc taagagatat tttaaaccta cataaaggtt ctcttattga
    82741 actggatact ttagcagacc aagatgtgga aatactaata gataataaag tgttggctta
    82801 tggaaaagta gtggtggtag atttaaattt tggtgtaaag ataacaagta tagtaagtga
    82861 agaagatatg gtaaaatctc ttgtttagag ataacatcaa ttaatactta aggcatgagg
    82921 tggtacttat tttaaactta aatgatataa aaaaagatat attaaaactc aataaaaaag
    82981 actcatgttc tctatataat gaatctatta ataatataaa taataattgt atatcgagtg
    83041 gattgaaatt tttaaaacaa gcaagagatt taaacccaga tgatgttgat atattaaatc
    83101 tcacaggtct tgtaaattta ctaaaatgta attttgatga ggctgtagaa agtttctata
    83161 agagttcact ttgtgaaaaa actgctctgt gtgaaaagta tataaacatg cttacatctg
    83221 aggagttttt aattttcttt gaaaggtaca atcaactcat aaggttaata aacagaggaa
    83281 tgtataaaga agctatacaa gggtttaaac ttataactga gcaatactgt gatttaatag
    83341 aaccttatga attgcttgcc ttactgtatg acaaggaaga agaatatata aaatttgatg
    83401 aatgtttaga agtattgaag attattgata aggaaaatta tttattaaat caagaaaata
    83461 acacattaga tatgtataat agtgctaata tacaaactaa aagtaatata aaagtagatg
    83521 attataagaa tgagttctta cataaaagta gtagtaacca taaaattaat gattataatg
    83581 atgtaactaa agaaaagagt tcaagcaaaa accagaaaag ttcagattct aataagaaaa
    83641 aaagtattaa aaaaaataaa tacctatata tagccataat attaggaata ttattagtag
    83701 gacaaagtat atatagttct tataagatga ataatttaac tgataaaata tctaaaaata
    83761 atgaaaccaa aaatgaagag tcaatagatt ctaacttgac taagaaagaa aataatatag
    83821 aagaaaatga agatatgagt aaggcttcta atataaataa gagtaataaa aacattaata
    83881 aagaggatga tgtaaaatct aaaaaaaata ctgtagaaaa tgaagatgat aaagattctg
    83941 acttatttac agaggatgaa ttgatgtcta aggcgaatac tttaaaatca gaaaagaaaa
    84001 ctaaatcttc tatacaacta tataagaaag ttgcagatat aggtgaaaat aaagggaata
    84061 catctgaagc aacttatcaa gttgctattc taagtgaaaa gttaaaagac tataaaactg
    84121 ctgaagaata ttataaaatg tatgtagaaa attactcaga aaaagatgct tattttgatg
    84181 aatcttatta taatttaggt atgatgtact ataacaatgg tgatttaaaa aattctaaat
    84241 tgacattaaa gaagttggtt aataaggtac caaatagtat gtataataat tcaaaagtaa
    84301 aagaaatttt aaaagaagaa tagttaaatt agataagaaa aataaattat tttattttaa
    84361 aataatatga ttataatata ttgacatacc attttaaaaa atttaaaata ttaattataa
    84421 aatgaggagg gataaaaaat ggaatttgaa aaagggagta tttcaattca tacagaaaat
    84481 atttttccta taattaaaaa atggttatac tctgataaag atatatttat aagagagctt
    84541 ataagtaatg gatgtgatgc agtaagtaaa cataaaagac ttgtatcact aggagaaata
    84601 tcagaaaata agtcatcaga ttataaaatt acagtatctg taaataaagg agaaggtaca
    84661 cttaaattta ttgacaatgg aattggtatg actgaagaag agataaaaaa atacataaat
    84721 caagttgctt tttcaggtgc tgaagatttc tttaataaat ataaggataa gatggaagag
    84781 tcaaatgaca taataggtca ttttggatta ggattttatt ctgcatttat ggtgtctaaa
    84841 aaggtacaaa tagataccct ttcatataca gaaggtgcaa ctcctgtaag atggatatct
    84901 gaaggtggta cagaatacga aatatctgaa tcagatacta gaaatgatag aggaactact
    84961 ataacactat ttattgatga tgatagtaaa gaatttttag atgaatttac tgtaagagga
    85021 ataataaata aatactgttc tttcttacca gtagaaatat atttagaaga tgttgaaaga
    85081 ttagaaagag aagctaaaga agcagaagaa aaagctaaaa aacaaaagga agatggaaaa
    85141 gaagagattg tagatgcaaa agtaattgag cctttaaacg acactaatcc tctatggtta
    85201 aaatctccaa aagactgtac tgatgaggag tataaagagt tttatagaaa ggtattcaat
    85261 gtatttgatg aacctttatt ttggatacat ttaaatgtag attatccttt caatttaaag
    85321 ggtatacttt acttccctaa attaaaaaat gagtttgaac tgactgaagg aaaagtaaaa
    85381 ttatacaaca atcaagtgtt tgtagctgac aatataaaag aagttatacc agaattttta
    85441 cttttattaa aaggtgttat agactgccca gacttaccat taaatgtatc aagaagtttc
    85501 ttacaaaatg acagagacgt aagcaaaatt tctaagcata taattaaaaa agtagctgat
    85561 aagttaaaat ctctttgtaa aaatgaaaga gaagaataca ataagttttg ggatgatata
    85621 caaatattta ttaaatatgg ttgcttaaaa gatgaaagtt tctatgagaa ggtaaaagaa
    85681 tgtatattat tcaaaactat tgatgatgag tatataacat tacaagatta tttagaaaaa
    85741 tgtaaggaca aacatgaaaa taaggtattt tatgtaagtg ataaggaaca gcaatctcaa
    85801 tacattaaac tatttaaaga atacgactta agtgctgttg ttttaaactc atcaatagat
    85861 actcatttta tttcatttat ggaatataaa gagaatggag ttaagtttaa tagaatagat
    85921 gcagaccttt ctgatgtatt aaaagataaa aatgaaaata aagatagtga agaaaacaaa
    85981 gaagagatag ctaagataga aggtctgttt aaagaagctg ttggagaaag agtgaagcat
    86041 tattctgtag aaggattgaa aaatgaagac actccagcta tggtgttagt atcagaacaa
    86101 tctattagaa tggcagaaat gcagtcaaga tttgctggaa tggatttagg aatgaatttt
    86161 gaggaagaaa aaactcttgt aataaatgag aacagtccaa taatcaaaaa attggtttct
    86221 cttaaagatg atgaggaaaa gaaagataag attacgctta tttgtaacca gatagcagat
    86281 ttagctttac tttctaataa agaattaaag ccagatgagt tagattcatt tgtacaaaga
    86341 agtaataagc ttatgagtct tttcatagaa ttataagatt gaatttgaat acattgaagc
    86401 aaatttataa aaagtattca atatcagtga tgataaagaa gtgtctcaaa atgaactttt
    86461 cagttcatgg ggcgcttttt ttatgtgaaa ttaaatttat tttaatcatt tcaacaatga
    86521 aaaatatatt tatctctatt ttgagacaga ccattcttta tttttttatc tttggttaat
    86581 ttttaaatat ttaagtaggt tctaataaaa aactctattt agttaaatat agttaacttg
    86641 atatataata agataataca tataattaag taaaagattg ttttttagtt tatgtttaaa
    86701 tacataatta cactttgtta aaaacataaa attattacta aagtagaaat aggaggtttt
    86761 agcatgaatt ttaattataa tttgccagta aatatcttat ttgggagagg cagaattaat
    86821 gatgtgggaa aagaagtatc taaatatggc aaaaaagtat tgatagtaac aggtaaaaat
    86881 agtacaaaga aaactggatt acttgataaa acaatagatt tactaaaaga ctctaaaata
    86941 gaatatgaag tttttgatag agtagaacaa aatcctctta taactactat atattcagga
    87001 gtagaaatta taaaatcaac tggatgtgat tgtgttttag ggcttggtgg tggaagtatt
    87061 atggatgctg ccaagagtat agctttttct tataaaaatt caggagattt aaatgattat
    87121 atatttggaa ttagacaagg tgaagaagct ttacctataa tcttagttcc aacaacatca
    87181 ggtacaggta gtgaaggaaa ttgttttgca gtacttacaa attcagaaac taaagataaa
    87241 aaatctataa agaagaatag tatgtatgca aaagcatcaa taattgaccc agaacttatg
    87301 gttacaatgc caaaacatat aattgcatca gttggatttg atgcacttgc ccataatatg
    87361 gaagcatatc tttctaatgg aagaaaccct cttgcagatg tacaagctat ttatgggatt
    87421 gaacttatat cagaaaacct aataaaggta tataatgatg ttaatgattt agaagcatgg
    87481 gaaaagataa cacttgcaag tactattgga ggaatgacga ttggtacagc gggtacagcc
    87541 ttgccacatg gaatggagca tcctgtaagt ggtcttagag atgtaatgca tggaaaagga
    87601 cttgcagctt tgactcctac tattatagaa agttcatggg atagtgatat tgaaagattt
    87661 ggtaatattt caaaggtatt aggaggaact tgtgcagaag attgttcaga tgcaattaga
    87721 aatttcctta aaaaaataga tttagatata aagctaagtg atttaggtat tgaaaaatca
    87781 gatatagatt ggttaactga taattgtatg aaaatatcag ttgcaaatat taagagacat
    87841 ccaaagtatt ttaataagga acaaataaag gaaatgtacc ataagtcttt ataatttgac
    87901 tttacatatt tagttttata taaaaattat aaattaataa taaaaaatta taagtaatta
    87961 atagtaaaaa aattgtgtat agaagttata tatataataa atttgtctta agcttttatt
    88021 ttactttcta ataaataaag gagtttaaaa aagggaagat taattaagta atattttata
    88081 aaattcttcg atttaaaaac tttaagtaga ggtgaaataa atgtttaatc ccaaaagaat
    88141 aatattcgaa aaaggaactt tagacactga tgtgggtaaa aaaatataca ataaatttag
    88201 agataataaa gatgtagaga taattaatat atcatcaaat aggattaaag aacatattcc
    88261 aggtgaaaat ctatatgaac aatatagaag tgggaagcag actatggtag ttgggattag
    88321 aaaaagtctg aagtttcaaa catgtaaacc ttctgctaat tatcaactac cacttgtcag
    88381 tggatgtatg ggaagatgtg agtattgtta tttgaacaca caattaggtg ataaaccatt
    88441 tataagggta tttgtaaatg tagatgaaat acttgaacag acaaaaaaat atattgaaga
    88501 tagaaagcca caggtaacca tatttgaagg ggcagctaca tcagacccag ttccagtaga
    88561 gccatatact aattctttga agaaaacaat agagtttttt ggaagagagg aaaaaggaag
    88621 atttagattt gttactaaat acagtgatgt ggatagctta ttggatgctg aacataataa
    88681 tcatacagaa atacgattta gtatcaatac tcctagaatt ataaatgaac atgagcatta
    88741 tacagcctct gcaaataaaa gaatagagtc agctgtaaaa cttgctaggg ctggttatca
    88801 gattggtttc ataatagcac ctgtgttttt atatgaaggt tggaaagaag agtataaaaa
    88861 tctgattata agtataaaag aagctttacc aaaggatttt gataaaaaaa ttatatttga
    88921 agttatatct catagatata caactaaagc aaaaaataga atactagaga tttatccaga
    88981 tacactattg ccaatggaaa atgaagatag aaagtttaaa tacggtcaat ttggatatgg
    89041 taagtacgtg tatgataaag aacaattaga tgatatgaaa gagttctttc ttaaggaaat
    89101 aaatggagta tttaaaaata gtttaataaa atatataata tagcaaatct tacctaaaga
    89161 tttgctatat tttattttta tatattttat gtttataata aagcaatgag atttagcact
    89221 atcatataag aaaattaaaa agggcactat ctatcaagaa cattttttct agttttgata
    89281 ctataaagga taagagtaac aaaaatatca ggaggagtta tagtatgcat gcatgggagt
    89341 ctattcaaat tacattggat ttaatagaag caaatttatc agaagaaata tcaattaatg
    89401 aattagcaaa taaagcaaat ttatcaccat tttactatca aagactattt aaaagattgg
    89461 taaataagac tgtaatggag tatataaagc ttcgtcgtct tgcaagagct tctgaatact
    89521 tagcagaaca taagaatcgt atacttgatg tagctttaaa ttttggattt gctagtcatg
    89581 agacatttac acgttccttt aaaaaagcat atggattaac tccagaaaaa tatagagcaa
    89641 atccagtaaa actcaatcac tttattaagc cagaattaat tttaaattat gctatggttg
    89701 atgaaggtgt tccactgatt gcagatgata tagtgattga agtcaatcgt aagacattga
    89761 gtaatccaag gacatttgtt ggaatagaaa tagaagtacc tatttgccag ttggtgggcg
    89821 gtgaaacaac tggaattgca atagtagagg aattatggat gaaacttgga agtcaaagac
    89881 ataatatacc aaatcaaatt ccaggtggaa atgaatttgc tgctctttat atgggaaatg
    89941 caaaagaagg aaattgtatg tatatggcag gtgtagaggt agagtcaggt acatcagtag
    90001 aaggatatag tacttttgag ttgccagcta aagaatattt agtatgtgga tttgaggcag
    90061 aaaactttaa tgagttagtt aattcagctg tttttaaagc agataaattt atggaaagat
    90121 ggatgaagaa acataattta acaactactg attttgcaat tgagatgtat taccccacta
    90181 cacctgaagc agcatatctg gaacattgga ttgttccggt tcctattgaa caatagaaag
    90241 gatgatgaat atgaattggc aagatgcgtt ttttcaagat actaaaccta catttgagca
    90301 aattaatgaa tttattaata atccattatg ggacaagtta aataaaactt tggtttctac
    90361 ttataatgta gaacctaagc ttgaatacag taaatgttca atgcaaagag gttggaatgt
    90421 aaaatataaa aaaagaggta aatcactatg tactttatat ccacaagaag gttattttaa
    90481 agctttggtt attgtaagtg aaagcaatag agtagaggtt gatttattta ttaatacttg
    90541 ttgtgattat atcaaaaaaa tatataatga ggtaaacttt tttaatggaa gtaaatggct
    90601 aatgattcaa gtagatagtt tattggtatt aaacgatatg cttgaactaa ttaaatttag
    90661 agcttaacat atagaacagg atgaatatat aagtcatcct gtttttatat tcaatcagat
    90721 aaattaatat atagtctata atatgaataa tttagtaaat ttaaatttac tttatctttc
    90781 tacattcttt gcaactaagt ccacatgtgt ttttttcttg catattagta gcaccccaat
    90841 tagcaaattg ttgtaaaata ggcacaatac ttttaccttt acttgttaat gtatattcaa
    90901 cttttggagg aatttcatta tattgtttac gatgaacaat accagtagac tctaaatctt
    90961 ttaatgattg agctagcata gtatttgtaa tgccatccaa ttttcttttt atgctactat
    91021 atctaattgg attttcaact gctaacatac atataatagg taatttccac ttaccaccga
    91081 caatgtctaa tgcataacgg attggacagg ttaattcttc aacgttttta gttatatttt
    91141 tttcagtatt tatactcatt ttaattactc cttagttata gtagtatctt ttttatactt
    91201 tatcagaaaa aactgcatac ttgttttttc tgtattttat attaaaatta tatcaaagga
    91261 taatccttaa tacaagtatt taaaaggggt gtaagaatta tgaaagcatt agaatttttg
    91321 aacaaggcac gagtttatta tttagcaaca gttgatgaga acaatcaagc acatgtgcgt
    91381 cctttaggat ttgttatgga atacaatggt aaacttacat tttgcacatc taatcaaaag
    91441 gatatgttta agcaacttat ttttaatcca aaggttgaac tttgttgtat agaccaaaac
    91501 cttaatactc tacgtatttt aggtgaagca gtatttgtta catcaaaaga aacacaagct
    91561 aaggcacttg aaataatgcc aagtttaggt cagatgtact ctgtaggaga tggtaagttt
    91621 gaaatattct ctattgataa ggcaaaagtt agttgttgtt caatgagtgg taaaaagatt
    91681 gatgtagagc tttaattata attgaatcga catccatagt gaaaattaag aaaacgttat
    91741 tactgaaatg ttgatagatt taatttaaat gcaataaaaa gatttttaaa taatgaatat
    91801 gtaaaaattt ttagttatta gatgtgtatt tcaataatga tatactattt tgaataatta
    91861 catactagaa ataagataat taaaatttac tttataatgg gatagatttc ttttaaaaaa
    91921 tattttaact ataattgatt tttatttaat ctgaaaaaaa tattatgact ataaaaaatt
    91981 gctacttatt atttggatat ttttatatat aaataataag tagcatgact ttatacatta
    92041 ataatgatag aatataaatt aatagataag atatgatttt aaaaggagtg atataagatg
    92101 agtaaatata gttctttatg ggaatatgtt aagaaaaaca atagtcaatc gtttaaatta
    92161 acttttgaag aaataaaaga tattgctggg atagagatag accattcgtt tttgaaatat
    92221 aaaaaggaat taaatgaata tggatatcaa gtaggaaaaa tctctttaaa agagaagact
    92281 gttattttcg ataaaattgg ttaagacata aataattaca tataataaaa taatttgtat
    92341 tgatgattat tacaaataaa aaagggcgta gcactatttt ttagtgtcac agcccctttt
    92401 ttgtttataa ttatgtacat ttcacattat cacgatataa gcatttttct tatgagaaaa
    92461 ttaattagaa ttatttttat tcatatttaa attatttaaa ttgttttccc agttttttat
    92521 ctccttttta acttcttcac ttaaagtatc acttgaagat attttcttta atttatcatt
    92581 caaagatttc ttttgttcct ctgaaaggtc tgtttttatt gtaggatcaa taatatctat
    92641 tacatctttt acatcaaaat caacaaattt gcacagttct tctagatgat caattagaaa
    92701 atctagacct tcatatgacc attctttata atcttttccg ttttttaata gaaactcatt
    92761 cacttggtaa ttctgatttg ctaattcaaa gaatgaacct gaaggatcca ttatatcatt
    92821 tatagagttt tcatagttaa caatattaat ttgtcttatt aatttctctt tttctgttaa
    92881 gttgctataa ttcttgttaa caaaagctac taatccaaat tcaaagttta aaattgaatc
    92941 tttacgtttt tttactgaat cttctccaaa ttccctaaga ccttctcaat ttttatcaat
    93001 ggctttatct ctaatctcta ttaattgttc tatacttaaa ccttctaagt ttttaggtac
    93061 tatttcttca ttattcttag taacttcttt caatttattg ttagtatttt tattattgaa
    93121 aataaatata gcagttaata aacttaaaat tattactaaa ataattaaac ttacattttt
    93181 tttacttaac atattaaacc tcctttttta aataagtatt gtacttgtga aaaataaatt
    93241 tgtttatgaa gataacattt actactgttt gttctaaaga ttataataga atattttttt
    93301 gatataatct atatttttct tattaaattt tcttattaga tatttaatat caatattttt
    93361 tagatagaaa agattttaat a
//
LOCUS       DAFAZV010000013        92687 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFAZV010000013 DAFAZV010000000
VERSION     DAFAZV010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 92687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92687
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.013"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..193
                     /locus_tag="KOU88_001379"
     CDS             <1..193
                     /locus_tag="KOU88_001379"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="iota toxin protein Ia"
                     /protein_id="HBK3211280.1"
                     /translation="YRELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTKNQNEISL
                     EKFNEFKETIQDKLLPYNR"
     gene            168..1735
                     /locus_tag="KOU88_001380"
                     /pseudo
     CDS             168..1735
                     /locus_tag="KOU88_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021426623.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iota toxin protein Ib"
     gene            complement(2387..3388)
                     /gene="trpS"
                     /locus_tag="KOU88_001381"
     CDS             complement(2387..3388)
                     /gene="trpS"
                     /locus_tag="KOU88_001381"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBK3211281.1"
                     /translation="MSEKKVILSGAQPSGKMTLGNYLGAIKNWTELQDNYDCYYSIVD
                     LHAITVPQDPKVLRANTIELLAQYIACGLDPEKNTIFIQSHVKEHVELMWVLNTMTYM
                     GELSRMTQFKDKSQKSEANLNAGLFTYPVLMAADILLYQTDLVPVGDDQKQHLELARD
                     LANRFNNRFSPTFVVPEGYYPKGGARVMSLQEPTKKMSKSDSNENAFILLADDSDSIK
                     RKIKRSVTDSLGVVKYNDEQPGIKNLIDIYSNLSKKSVEEIVNMYEGKGYGIFKEDVA
                     EVVSEALRPIREKYVDLLNNKDYLEKIYSMGAEKAEKQARKTLRKVYKKVGFIERRY"
     gene            complement(3411..4109)
                     /locus_tag="KOU88_001382"
     CDS             complement(3411..4109)
                     /locus_tag="KOU88_001382"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBK3211282.1"
                     /translation="MNVIGIIGAMDEEVSILVDLMDIRETIKKASLEFYKGILEGKNV
                     VLVKCGIGKVNSALCAQILISEFKVDAIVNTGVAGALNEKLDVNDIVISTDAIQYDVD
                     TTAFGDPKGVIPRMKTSVFKADERLIDAAYKSSVEEVKTHKVLKGRVVTGDKFINSKE
                     LKEELLNDFGGYCGEMEGGAIAHVCYLNNTPFVIIRAMSDKADGSADVTYDVFVHDAA
                     NNSKDIVLNMLKSI"
     misc_binding    complement(4152..4392)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(4483..5886)
                     /locus_tag="KOU88_001383"
     CDS             complement(4483..5886)
                     /locus_tag="KOU88_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK3211283.1"
                     /translation="MEKKKIGLWSLVFMNVSALYGIRWIAKSTASSFGLGLGAIPMWL
                     LFSFIYFVPGALICAELASTYQKGDGGLYDWVKEAFGEKYGFLVSWLNWTAKIFWYSS
                     FLTFLAVNVSYTIGNPALADNKMFVLILSLIIFWALSLIATKGISFTKIFTNTGALGS
                     TIPSAILIIFSFVAVFVLKKHDIASTYTIASMTPKLNMDAFVAISAIMFGLAGAETAA
                     NFITEIDKPEKNFPKAILISAGIVASLYVLGSIAITMIIPPDQITASKGVLDALSAVC
                     ASLGIGSWLVQLIAFGIAFSVLGAIVLYIASPIKMLFGSVKKGIFPDSLVEVNEHKIP
                     SKAVILQAIIVTIILLVTTLMPSVDAIYNVLVTMTALTALFPYVLLYASYIKLRKERP
                     DEIRPYTMAKSTSTCLGLAKMVLVVTVVGILLSAAPVMPTFAENVIYEIEMIGGGLLV
                     ILSGLWLWNRYEKKTAK"
     gene            6383..7459
                     /locus_tag="KOU88_001384"
     CDS             6383..7459
                     /locus_tag="KOU88_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK3211284.1"
                     /translation="MKAQRLNAVLEQMKKDDISQMLVSDPTSIFYLTGVLIHPGERLL
                     ALYLNLNGNNKLFINELFPVSEDLGVEMVWFNDTQNPVEIITEHIDKNATMGVDKNWP
                     ARFLLNLIELGGGSKFVNSSYIIDTLRMCKDEEEKELMRIASKLNDKAMEQLKATVSG
                     ELTEKQLVGKLSKIYEDLGTDGFSFDPIIGFGPNGANPHGEPGNALVKPGDAIILDIG
                     CIKDNYCADMTRTVFYKEIPEKGREIFEIVLEANKRAEAIVKPGVRFCDIDAAARDYI
                     TEKGYGQYFTHRTGHSIGLEVHDKGDVSSINTDTVQPGMIFSIEPGIYLPGEFGVRIE
                     DLVLVTEDGCEILNKHDKEICVVG"
     gene            complement(7562..8404)
                     /locus_tag="KOU88_001385"
     CDS             complement(7562..8404)
                     /locus_tag="KOU88_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK3211285.1"
                     /translation="MDKIKLIVDSACDLPDDIIEKYNIEVVGLNVSFGEESYISGKEI
                     DNETFYRKMSESKVLPKTSCPSPDKFLEAYHCQEESVLVINISSGLSGTYNSALLAKD
                     MFEKEGNNKKVEVIDSLSGSIGIGQLVLKAAILIKEGKEIEEIVSIINKYKDNPPFFG
                     TLETLENAIKGGRINPIAGKIINTLNFKAIIQVADGVVTPIDKARGEGNSLKKLITLV
                     ESKIKDKEEKVLFIGHANCPEKAQKVREVMEKDVKYKDVVICEIGSVMGTYTSKGAIL
                     ITAI"
     gene            8588..9160
                     /locus_tag="KOU88_001386"
     CDS             8588..9160
                     /locus_tag="KOU88_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3211286.1"
                     /translation="MKTNNMKQAILSSATNLIAKNGVQNTSLADIAKDVNISKGTLYY
                     HYASKDDIIYDIADTHLEVITSAILNCVKNVKSKNSQIEMVNLILEKISTIESRGRVH
                     MYLICEAITSNNDLKERIRLKYIEWRTTLKSEIVESLEKYNSSENEQDAESFSFLLMS
                     IVDGLVVQSLLKTEKIPYENIASFLVNHWI"
     gene            complement(9323..9595)
                     /locus_tag="KOU88_001387"
     CDS             complement(9323..9595)
                     /locus_tag="KOU88_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211287.1"
                     /translation="MLRERFVVRNHHNPHTSGCCGTGGEGCCGGDNHEHSHQHSHSHG
                     HEHEHVNGVGHDHNHDDGFSGNHEHSHEHTHTHGHEHSDGHTHEHK"
     gene            complement(9709..10581)
                     /locus_tag="KOU88_001388"
     CDS             complement(9709..10581)
                     /locus_tag="KOU88_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK3211288.1"
                     /translation="MYGESKKLSIDNNIFLQYCLIILGMILSTLGINLYLAPAKLLSG
                     GVAGICVILYKLFGINQGISSFLMNIPIFIIARKYFDNKFLLISFVNMLLFSLALGLT
                     QDIAKYFPIDDTMLQCIYGGALTGIGMGLTFKARATAGGLDIIAAIMKRKYDIPMKNT
                     FLFINFFVVCAGAFLFGAKLVMYTLITMYIISFTMDIGKDCFDRKKSILLISNKYDEI
                     SKVIMNKMGRGVTFLEAEGAYTQNKKKMIYCIISANEIGKFKDLIYDMDSEAFISVNN
                     VEEVKGGGFKDKFL"
     gene            complement(10877..13984)
                     /locus_tag="KOU88_001389"
     CDS             complement(10877..13984)
                     /locus_tag="KOU88_001389"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBK3211289.1"
                     /translation="MAKFKPLVDSSVKQAEAQVFDYWKDINILEKTLEKGKDDPSFVF
                     YEGPPTANGNPGVHHVLSRTLKDSVCRYKTMSGYQVKRKAGWDTHGLPVEIQVEKELG
                     LTSKQQIEEYGIAEFNQKCRESVFSFEKQWRIMTERMAYEVDLDNPYITLDNNYIESV
                     WWILNKFNKEGYIYEGHKILPYCPRCGTGLASHEVAQGYKEVKTNTVIAKFKKKDADE
                     YFLAWTTTPWTLPSNVSLTVNADVDYLKVKKGDEVYYVSKPLADKVLGEDYEVLEEMK
                     GKDLEGLEYEQLMPFVEVDKKAFFITVGDYVTTEDGTGIVHTAPAFGEDDYNTGKRYD
                     LPVIQPVDETGKFTSTPWEGRFVMEDGLDVEIIKWLASENKLYSKEKVVHNYPHCWRC
                     QTPLVYYAKPSWYIEMTKLKDKLIENNNGVKWFPSFVGEKRFGNWLENLNDWAISRTR
                     YWGTPLPIWRCECGHTDSVGSRAELAEKAIEDVNPETVELHRPYVDDIHLKCEKCGKP
                     MTRVTEVIDCWFDSGAMPFAQHHYPFENKENFDQLFPADYISEGIDQTRGWFYSLLAV
                     STFVLGKAPYKSVLVPDLVLDKDGKKMSKSRGNTVNPMELFDQYGADALRWYLLYVSP
                     PWTPTKFDMDGLKEIQSKFIGTMKNVYNFFTLYANTDDINPTEFFVEYKDRPELDRWI
                     LSKFNNLMKDVEENLAIFELNKTLRMIQDFINDDLSNWYIRRSRRRFWATELTEDKKA
                     VYNTTYELLHGLCRAIAPFAPYMSEEMYRNLTGEVSVHLAEYPKCNEELVDTKLEEKM
                     DLAKNLVTLGRASREVERIKVRQPLQKVLVDGKFEDTISDVVDLIKEELNVKEVIFAK
                     DLDEYMNFSLKPNFKEAGPLLGSKMNLFVGALSKLNAHETANKLEKGETLTVDLDGEA
                     FEFNKDLVLIGITAKEGFNVSVENNLFVILDTKLTEELINEGYAREFISKVQQLRKSN
                     NFEVLDNIVIEYCGDDEIAKAVDHFNEYIKSETLALEINRVDDKSLEEQNLNDHMTGI
                     KVIKK"
     misc_binding    complement(14077..14309)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(14484..15011)
                     /locus_tag="KOU88_001390"
     CDS             complement(14484..15011)
                     /locus_tag="KOU88_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBK3211290.1"
                     /translation="MLTPIEIENKEFKKGLRGYRDEEVDEFLDIIKEDYESLCRENTA
                     LKEKLGLYQDQVNKYENIEETLKATLITAQSAAEDTCSAANKKAKIIVEEADLKARQI
                     IEQANNRVIEIRKEYDALVKEFKIFRNKFKSLLEDEIRSVDEIFYDVDEKCVNAFEGT
                     TVYNYSNDEAATTLE"
     gene            complement(15046..15831)
                     /locus_tag="KOU88_001391"
     CDS             complement(15046..15831)
                     /locus_tag="KOU88_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBK3211291.1"
                     /translation="MDKLKLTNHIKDIDLKNKMFKVIDKANSCIKNYDVKSTEFLNPY
                     EVKNAVAILNSTNEIKYSVDGGYEQAERSTVFIYPFYMEYEDIEDTLRFLQIEGNFKF
                     KNISHKDYLGSILGLGIKREKIGDIIIHDSFCQVVVSSDICDFIIVNLEKVSRNNVIV
                     KEISRENIVNSSSKYKEVSFTVSSDRLDCVISGIYNISRQDSAKYINGEKVHVNYEKI
                     TSTSKIVKNDDLISIRGKGRAKVTQIGDITKKGKIKVQARLIV"
     gene            complement(15841..16098)
                     /locus_tag="KOU88_001392"
     CDS             complement(15841..16098)
                     /locus_tag="KOU88_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBK3211292.1"
                     /translation="MGTIRIALYYLLDIIAWMIVIKSLMTWFPNGRQSKIFDILENLT
                     EPIEGPIRSIMYKYTNGPIDFSPLIAIVLLMFLRQLVLVIF"
     gene            complement(16117..16575)
                     /locus_tag="KOU88_001393"
     CDS             complement(16117..16575)
                     /locus_tag="KOU88_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBK3211293.1"
                     /translation="MSNGIISKFKNWIVDEEEDYIEDEYESGMDDIVQEEEMNSGFST
                     AKANKIVNLHTTSQMKVVIVEPKVYDEAATIADHLKQRRAVIVNLEGLTNSEVRKSIF
                     NFMNGAVYVLDGSIQKVSKSIFILAPNNVDIDANMKKELESKAFFPWQNK"
     gene            complement(16615..17319)
                     /locus_tag="KOU88_001394"
     CDS             complement(16615..17319)
                     /locus_tag="KOU88_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBK3211294.1"
                     /translation="MGSIKDNLSEIRNKIDKAAKKVDRDSKEITLLAVTKTVDVDLVN
                     EAMREGITSVGENKPQELARKYDIIGDKLNWHLIGTLQTNKVKYIIDKVCMIHSLDRI
                     ALCEEIQKRAEQINREIDCLVQVNISKEESKHGLDREEVVDFVKEVSEKYKNIKIKGL
                     MTMAPFIEDEDEIRGVFKGLKDLSKQIKELNIPNVGMDVLSMGMSHDYEIAIEEGATI
                     VRVGTSIFGERNYNKK"
     gene            complement(17329..17964)
                     /locus_tag="KOU88_001395"
     CDS             complement(17329..17964)
                     /locus_tag="KOU88_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211295.1"
                     /translation="MKKVKYTRLVILGILIYLVFNILVMIISKNVDTLVLKNEKVDAK
                     IHVKGTIEKDANDQSNYLSTYISKEDSNNFKKNQNVIIEYHEQKLDAKVYKIYENNNK
                     IMVKLKISNQIVANQDTSVEEFDIIYNQMECLKIPKTSIKTKDNKRGVYVIDEQSQSV
                     KFVILEGITYENESSVFVDYYKNDINGVTSVNLYDKIILRPNSINTNIRIK"
     gene            18345..19385
                     /locus_tag="KOU88_001396"
     CDS             18345..19385
                     /locus_tag="KOU88_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3211296.1"
                     /translation="MSEILLGTGLLLLVLCCFTIFSYKAPYGMKAMGALANAACATFL
                     VEAFNLSLLGDVLGMEFFRSVGAANGSLGGVAAAILVPLALGVSPVYAVLIGLSCLDF
                     SILSGFVAGYFVSFLIKFIEKKVPPGVDLVVVILLCAPLSRLIASNVDPLVNSTLLQI
                     GQVLIEATNISPIIMGIILGGLITVVGTSPLSSMALTSIIGLTGLPMAIGALGAFGSA
                     FMNSTLFAKLKLGSKKDIISVAIEPLTQSDIISANPIPIYSTNFFGGAFSGIIVALMG
                     LVNMTPGTATPVAGFAIMFAYNPVQQVLITAGLCALFNVIAGFLGSKIFSTFKVLTAG
                     EIRGTDVEEEIA"
     gene            complement(19873..21228)
                     /locus_tag="KOU88_001397"
     CDS             complement(19873..21228)
                     /locus_tag="KOU88_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009170073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HBK3211297.1"
                     /translation="MNVGNILETIKMIDEEQLDIRTITMGISLLDCIDPDGDKAREKI
                     YNKIMSSAKDLVKVGKDIEREFGIPIVNKRVSVTPISIIAGATDENDYVKFAQTLDKA
                     AEDLGIDFIGGFSALVQKGYTKGDKILIKSIPKALASTNKVCASVNVGSTRCGINMDA
                     VKEMGEIIKETAELTKDAKGFGCAKLVVFCNAVEDNPFMAGAFHGVGEADRIINVGVS
                     GPGVVKRALEKVKGEPFDVVSETVKKTAFKITRVGQLVAKEASSRLDVPFGIIDLSLA
                     PTPAIGDSVANILEEMGLEVVGTHGTTAALALLNDAVKKGGVMACSHVGGLSGAFIPV
                     SEDAGMIDAVIKGALSIDKLEAMTAICSVGLDMIAVPGNTTAGTLGAMIADEAAIGMI
                     NNKTTAVRIIPAPGCDVGDMVEFGGLLGRAPVMPINTNSSELFTQRGGRIPAPIHSFK
                     N"
     gene            complement(21254..21523)
                     /locus_tag="KOU88_001398"
     CDS             complement(21254..21523)
                     /locus_tag="KOU88_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010963800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBK3211298.1"
                     /translation="MKAILTVIGKDKPGIVAGISDELYKQNINIVDISQKILQDYFTM
                     IMIVDLEKSLNSFEKTVEDLVERGKKLSVDVKIQREEIFNSMHNL"
     gene            complement(21813..23768)
                     /locus_tag="KOU88_001399"
     CDS             complement(21813..23768)
                     /locus_tag="KOU88_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211299.1"
                     /translation="MKKYEIFIFMSIIVLCFISFPHKVFGQEENCLEDFERWVQENKN
                     NKEEIVYTLSCDMVIDEEFRFYIPYDSNFTIDTNKYKILIKNHGRFIIDDNELNIIGE
                     GGKEGVIHIENGGSISIGINNIIATDGTALYVEEGGDLHIKSSYESVEKIKANGKDAI
                     GIYTENDIRILNKDIEVNGEHAIGVYSKGDVEIEETSIKAYSSNNESGLLRDNNKLAQ
                     SIISESKKVYIIDDYNELIPSIAEDSGYNIVKCCHRGIGVFSDEIKVSKDDKIENIKF
                     PKYMVLETSSGNRLDIDVEWDFTDYYEKLEKGEDFNITGKFKTEMLNKEKIIINDDVV
                     PILNVSVIEKKPIDNLELEFQNTKNGYVAVLFYDMPYSASKVFVEYSSDGINWISEEQ
                     EDIRDQAILFFEDFKLRCFRVKVVGGLKEGYSNIVFKPGFIMGGGDNQETPDDEREND
                     DIDGDRGGGGRDDPDRDEDDNNQDGNNGNENNDSNNNQNNNNENNNNENDNSDEKQPN
                     TPKDDVESSTDSNENKNPHDIPKDGNKENNSDKEKGFYNKNSITENDDNYDLSSKSVF
                     GTNEHSFPYRESISNKNQDTNKNKSNISDYDGIINNNYKLESKEYNLKKDIIFLFCIL
                     TPIMIGSILIVNPDTRKSIIKFIKLKK"
     gene            complement(23951..25426)
                     /gene="spoIVA"
                     /locus_tag="KOU88_001400"
     CDS             complement(23951..25426)
                     /gene="spoIVA"
                     /locus_tag="KOU88_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage IV sporulation protein A"
                     /protein_id="HBK3211300.1"
                     /translation="MNNNIYEDISKRTQGDIYIGVVGPVRTGKSTFIRKFMEKLVIPN
                     IDNEFKKDRTRDEIPQSGSGKTIMTVEPKFVPADGVEIKIKDTVSLKVRMVDCVGYIV
                     EGALGHEEGGKQRLVSTPWSQEAMTFEKAAEIGTKKVIKDHSTIGIVVLTDGSVTGID
                     RKSYVEPEERVIQELKNLKKPFAVVLNTLSPKSEETSMLRSELEEKYEVPVLPMNVVE
                     MEEEDIEEVMEAVLYDFPLTEIRINLPKWVEGLERNHWIKSSIITTLKQSIIDIGKIR
                     DIEGIIQGFSELEFLEDTGVDNVELGEGVINIDLQTKQDLFYNVLEEKSGFKIEGDYQ
                     LLSLITRLSKVKNEYDKIESALIDAKIKGYGVVAPSLEELSLEEPEIMKQGKQYGIKL
                     KANAPSLHIIKADISTEVSPIVGNQNQGEEMIKYLMEVFEEQPADLWESNMFGKSLHD
                     LVKEQLQSKLYTMPEEIRVKMQKTLQKIVNEGSSNIITILL"
     gene            complement(25744..26763)
                     /locus_tag="KOU88_001401"
     CDS             complement(25744..26763)
                     /locus_tag="KOU88_001401"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBK3211301.1"
                     /translation="MEKVCVLGTGSWGSALALGLAKKGNDVSMWTRKEEQAKKINRTK
                     ENTDYLPGVLFPNNITISTDIEKTIKDCKVIVLAVPSQAVRSTCQKIKPFIKEGQVIV
                     NVAKGLEKGTGLRLSQVCEEELPQNPYVILSGPSHAEEVARDIPTTVVVASKDLKIAQ
                     MIQDLFMSPKLRVYTNPDIVGVELGGALKNIIAFGAGICDGLGYGDNAKAALMTRGIS
                     EMSRLGIAMGANMSTFAGLSGIGDLIVTCTSMHSRNRRAGILIGKGMSLEDTLKEVKM
                     VVEGITATEVAHDVAEKLDIDMPITNAIYSVIKKGSNPKEVGIELMMRSKKHEMEEVV
                     LGDDI"
     gene            complement(26794..27408)
                     /gene="plsY"
                     /locus_tag="KOU88_001402"
     CDS             complement(26794..27408)
                     /gene="plsY"
                     /locus_tag="KOU88_001402"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBK3211302.1"
                     /translation="MEIFSYIIIAVVAYLLGNISTSYIVAKRIAGVDIRTQGSGNAGS
                     TNVLRTLGKRAGAMTFLGDVLKGVMAVLISEFAARLVGIDTLLAGYLAVICVVAGHNW
                     PAVLGFRGGKGVATSLGAMLAVNPVITLMCLAVFILVVAITKYVSLGSVVGIGCSPIF
                     MIMVKNKAGLIVALFLTASVIYNHRANIKRLLNGTERKIGQKKE"
     gene            complement(27443..28762)
                     /gene="der"
                     /locus_tag="KOU88_001403"
     CDS             complement(27443..28762)
                     /gene="der"
                     /locus_tag="KOU88_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012063975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBK3211303.1"
                     /translation="MSRPVVAVVGRPNVGKSTIFNKFAGKRISIVENTPGVTRDRIFA
                     EVEWLDKYFTLVDTGGIEPDSEDIILSQMRNQAMLAMDMSHVILFIVDGKAGITAADK
                     EIAQLLRKTKKPVILVVNKIDSQSQFDNIYDFYELGFGTPFAVSGANSMGFGDLLDEI
                     VENFPAGLDTEYEEDIIRVAITGKPNAGKSSILNKILGEERVIVSPIAGTTRDAIDTY
                     FEKNGQKFLLIDTAGLRRKSKIYETIEKYSVIRAMSAVDRADVVLIVIDALEGVTEQD
                     TKVAGIAHDEGKGCIFVINKWDLIEKDNKTMSNYTKDIKEKFPFMMYAPIVFVSAKTN
                     QRMNKILDTVEYVSNEHSKRISTSALNEVIGEAVMLNQPPSDKGRRLKIYYGTQTDIR
                     PPKITLFINDKDLTHFSYQRYLENKIRENFGFEGTSIKFEYRQKNKK"
     gene            complement(28796..30124)
                     /locus_tag="KOU88_001404"
     CDS             complement(28796..30124)
                     /locus_tag="KOU88_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF512 domain-containing protein"
                     /protein_id="HBK3211304.1"
                     /translation="MEVNVKKVNNIISKVYKDSIAEEVGIEVGDLLISVNEQPIHDII
                     EYRFLLSDEYLDVEIQKKDGEVYIYEIEKDYDEDLGVEFTNPIIDQAKSCRNKCMFCF
                     IDQLPEGMRETLYFKDDDSRLSFLQGNFVTLTNMSEEDINNIIKYRISPINISVHTTN
                     PELRQKMISNKFAGKLYGIMKRLADAHIEMNCQIVLCPGINDGKELDRTIKELAQLYP
                     YVNSVAIVPVGITKHRENLVELNIFNDKSASKTIEQIHQIQQKYLEKLGTRFAFLSDE
                     FYILSNSELPGYEEYEGFLQFEDGVGMIRKLKTEIEEYLNILPEKILKREKKVSIATG
                     HSAYEFIQSMADAMMDKFKNLQVNVYEIKNKFFGETITVSGLLTAKDLKEQLEDKELG
                     DALYITRSMLKADEEIFLDNIELNQLEELMRIKIIPCLNEGKDFVDKILK"
     gene            complement(30362..30562)
                     /locus_tag="KOU88_001405"
     CDS             complement(30362..30562)
                     /locus_tag="KOU88_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211305.1"
                     /translation="MGMDIGLNEYTLAIVTLDKNMKNGGGCPIFYANDEKDLQNKALL
                     MSKCVGGMVHDMTNGTLIIVKH"
     gene            complement(30564..31496)
                     /locus_tag="KOU88_001406"
     CDS             complement(30564..31496)
                     /locus_tag="KOU88_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBK3211306.1"
                     /translation="MDRVFFVAVIIGITSRIIMLNLDQKQYPTQPNVLLSQLILAFVA
                     SSLGALLVPALINRSYTSITFLSLAAEQFRQVRANRRNTLQNLEEVQLVKRGAAFIEE
                     IARTYEVRNYMCIVTSFLTIGLYYVILAETKISEGMSLVISSICGLVLAFILKKLLTR
                     KSIGDIADVMPAEISFVDESILKVGDLKGITNIGLKSDREVYINRGVGIQIIPKNKDY
                     ANAGILFDSGQRQAIVYNIYSRLGLYGDYGEPSFVPLPRRNKEDESIMIAYLPVDKNV
                     EKVMEAVKSCPILSSSKGKNLSLKNYKIGKKGSA"
     gene            complement(31541..32473)
                     /locus_tag="KOU88_001407"
     CDS             complement(31541..32473)
                     /locus_tag="KOU88_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIEGIA family protein"
                     /protein_id="HBK3211307.1"
                     /translation="MEESLLNANLFRHSFIVALVVGILCRGLVLRVTDKQYPSRPQDY
                     LEQIIISGLSASLGAIALPALIDKEFAALTFFAVAIQQFQGLAEQERITLKNIDNEEL
                     VPKGDAYVEEIASTYESRSYISLFSALVSSIVYIVFARKYGLSFFYCTILAIVSGAIV
                     GLIFRRFLRRNSIADIADIVPAKISFEGPILMVNGVIITNIGLESTREKYRNECLAIE
                     VIPRDLGAFGIVNDIGQRQAIIHNLFIHMGIDRDVDEVDIVAISKTNLEKSTVVIPYM
                     PILKDIDVMIDVVKSTPIIETSKGKQSDFSRKTL"
     gene            complement(32528..33817)
                     /locus_tag="KOU88_001408"
     CDS             complement(32528..33817)
                     /locus_tag="KOU88_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3211308.1"
                     /translation="MEDLNSIYFFIVMLSIAIVILAVRYTITLRKYLKEFIYVSKKVS
                     NNEYHARLNISAKGELGELARNFNHMIKNMDKTLEEVQYKHLQLRSILKSISHGILAI
                     DVNGNILLINDEAKEMIKSEPNQLVEGHNINVVIKEEEILKQILQFIGSKDNETANIT
                     TKDDIVYKIKVDPVYLQNTNNVIIGSIVNIEDITKKVKLENMRSDFVANVSHELKTPL
                     TSISGFVETLKSNENIDVNTRNRFLEIIESESDRLKRLIDDILLLSFVENKDTLLMEN
                     VVVYDVFKEVYEITQHSASEKNIEVLYKCDDKSISILSNKDYIKQVFLNLVDNAIKYT
                     QDNGIVQVVVLKDEEKIVIKVIDNGVGIPKEDVERIFERFYRVDKARSRDVGGTGLGL
                     AITKHIVKSLNGCIKVKSELGIGSEFIVTILQKNFLK"
     gene            complement(33846..34538)
                     /locus_tag="KOU88_001409"
     CDS             complement(33846..34538)
                     /locus_tag="KOU88_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3211309.1"
                     /translation="MNTKVLVIDDEMHIVELLKFNLEVSNYEVSYSYDGFDGFIKAKE
                     IKPDLILLDWMLPNISGIEVLRKIRSDKDLKNIPVIMLTAKNMENDKVEGLEIGADDY
                     ITKPFSIKELLARISSVLRRYNLTSLGEENNILTTGNLKLDLSKHEVTKGSEKIELTL
                     KEFELLKLLIQNKGKVLSRNYLLDKIWGYEYYGETRTVDVHIRYLRKKIEDEDKSEKY
                     IETIRGVGYKID"
     gene            complement(34553..35314)
                     /gene="pgeF"
                     /locus_tag="KOU88_001410"
     CDS             complement(34553..35314)
                     /gene="pgeF"
                     /locus_tag="KOU88_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HBK3211310.1"
                     /translation="MMKDYINIKNVQDIKEYVNLSGNCEELDEKLNSVNLVITCKNID
                     AKNREDMLKVCKECDLTFENLTSNSQIHSDIVNIVNKDTIGKRRDGDALITNLEKVPL
                     LLFTADCVPISIIDAKNKAIGLAHAGWRGTFSNIGHKTIKLMSECYKTVPEDLVCIIG
                     PSIGPCCYEVSEDLVEKFNTILTNNDEKFYIIKEGSYYLDLWKINEYMLRCSGVKKEN
                     IINLNLCTSCRADKFHSYRKHNKASERIGTVLQIK"
     gene            complement(35311..35772)
                     /gene="nrdR"
                     /locus_tag="KOU88_001411"
     CDS             complement(35311..35772)
                     /gene="nrdR"
                     /locus_tag="KOU88_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBK3211311.1"
                     /translation="MQCPYCNYKESKVIDSRHTDLKSIRRRRECESCKKRFTTYEKIE
                     TTPLMVIKKDNSREYFDREKIKYGLLKACEKRPVSIDEIESIVVHIENEINKCFIEEI
                     ETKKIGEMVMDKLKELDEVAYVRFASVYRQFKDINTFVNELKSILIEKGDK"
     gene            complement(35794..36057)
                     /locus_tag="KOU88_001412"
     CDS             complement(35794..36057)
                     /locus_tag="KOU88_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBK3211312.1"
                     /translation="MIRVSDIMEKEIINVKNGKRMGFIIDIDMDIHEGKVVSFTIFGD
                     GSRSFFSRGGDEEVIFWNDILKIGCDTIIVNIGSELSLDEFEI"
     gene            complement(36161..36934)
                     /gene="sigG"
                     /locus_tag="KOU88_001413"
     CDS             complement(36161..36934)
                     /gene="sigG"
                     /locus_tag="KOU88_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigG"
                     /protein_id="HBK3211313.1"
                     /translation="MQVNKVEICGVNTSELPVLKNKQMKELLLQIKNGDEEARQQFVR
                     GNLRLVLSVIKKFNNRGENIDDLFQIGCIGLIKAIDNFDLSQNVRFSTYAVPMIIGEI
                     RRYLRDNNPIRVSRSLKDIAYKALQVRERLIRTNSKEPTVSEIAKELELEVESVVMAL
                     DAIQDPISLFDPVYQDNGDAIFVMDQVQDKKDTDENWLQEISLKEAIKKLNSREKLVL
                     DLRFYKGRTQIEVADEIGISQAQVSRIEKNALKNMRKYV"
     gene            complement(37026..37748)
                     /gene="sigE"
                     /locus_tag="KOU88_001414"
     CDS             complement(37026..37748)
                     /gene="sigE"
                     /locus_tag="KOU88_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigE"
                     /protein_id="HBK3211314.1"
                     /translation="MLRLKERIISFITMLGIKLKIIKPKGIYYMGGANILPPPLKPEE
                     EMELLQKLETDESVKSILIERNLRLVVYISRKFENTGIDVEDLISIGTIGLIKAVNTF
                     KLNKNIKLATYASRCIENEILMYLRKNNKKKTEVSFDEPLNIDLDGNELLLSDVLGTE
                     NDEIYKIIEEEIDRDLLVMALDRLSDREKQIMELRFGLIDKGIEKTQKEVAGMLGISQ
                     SYISRLEKKIISRLQKEMKKFV"
     gene            complement(37773..38645)
                     /locus_tag="KOU88_001415"
     CDS             complement(37773..38645)
                     /locus_tag="KOU88_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E processing peptidase SpoIIGA"
                     /protein_id="HBK3211315.1"
                     /translation="MFKGFKGGYMVYIEYYVIENLVINYIIISCTSILTKRYNPKKNK
                     LLGASLGGAYSVAYLYPSMNILFTVPFKIIIMSIITLISFRSKSKKDYVHVALVFYLV
                     NIFISGSTYFIIYFTGISHLKISFLIACTYVSCELLKYIYKDLKMLKYIKELTKTINI
                     NLLEKSFCCKALVDSGNLLKDPISQSDVIIVKSSVLEGFIPEKLLNINYEDIDMKKAQ
                     EIIGSLDDKTSGRVRIIPYKHAGSNKTSIIIGLKADYIEVDEQKIGNIILGISNFNDR
                     EYGAIMNPNILPGF"
     gene            complement(38935..40209)
                     /locus_tag="KOU88_001416"
     CDS             complement(38935..40209)
                     /locus_tag="KOU88_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBK3211316.1"
                     /translation="MIKLKKVLSLVMVGILSVSILAGCSKKEDSKGKEGKEKLVVWSA
                     PLTDHDADAWKPIFEKFEKENNCEIEFQIVPWDNYAEKYATAISAGEGPDIGYMYAEM
                     FPQFIEMGAVEDLTPYLEKSGTSDNYLYLDDAKMMGGIYGLPIEAANPGVLYYNKDIL
                     EKLGEKPPKTWDDFKRICEKATKDTDGDGKIDQWGLAQGWGSKVFGSLNWNWYPYLWQ
                     AGGDIYNDDLKSVKFNNAEGLKAANFINDMKKYIPEDALSKDSNEMIESVFGPGKAAF
                     TIMLSSAATSTFDKSFPDLNWGYVTSLEDKTVGSFASVDDLTLMSACKNKELGFKLLE
                     YMLSKESMEAFHKEIPRAPVAKGEKYQGDPRFEEMVTRDKHMYRPLTVGPHGVEIYEY
                     LWKQLQMMIAGDITPEQALNESAKYANGLLAQ"
     gene            complement(40493..41650)
                     /gene="ftsZ"
                     /locus_tag="KOU88_001417"
     CDS             complement(40493..41650)
                     /gene="ftsZ"
                     /locus_tag="KOU88_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBK3211317.1"
                     /translation="MLNFDVELEECAQIKVIGVGGGGNNAVNRMVEAQLKGVEFISVN
                     TDKQALYTSKAEYKVQIGEKLTRGLGAGANPEVGKRAAEESKDEIVKLLQGADMVFVT
                     AGMGGGTGTGAAPVVAGLAKEMGILTVGVVTKPFAFEGKIRMKNAEGGIAELKSKVDT
                     LITIPNDRLLQIVQKNTSMLDAFAVADDVLKQGIQSISDLIAVEGLINLDFADVTTIM
                     KDKGLAHMGIGSASGETRAIDAARQAIQSPLLETSIQGAKGVLLNVTGGPNLGLFEVN
                     EASTLVMESCDPEANVIFGASIKEDLGDEIMITVIATGFEGLQNGALDLDTKPKSSIR
                     SSLNTTVKQAVKEIEEEVIAEEKIEPPKKASIIEEDDDESMEIPTFLRRRR"
     gene            complement(41840..42193)
                     /locus_tag="KOU88_001418"
     CDS             complement(41840..42193)
                     /locus_tag="KOU88_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small basic family protein"
                     /protein_id="HBK3211318.1"
                     /translation="MLWVLGGLAFGVVVGYYIPFTYSMDYSIYMSVAILAIMDSIFGA
                     IKSNFEDNYDNVIFITGFIGNAILAILLTYIGEKLGVSLYYVAVLVFGMRLFNNLSII
                     RRYIISNIMNKKRKN"
     gene            complement(42292..42966)
                     /locus_tag="KOU88_001419"
     CDS             complement(42292..42966)
                     /locus_tag="KOU88_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBK3211319.1"
                     /translation="MKKKIVILGAFILGVFISTYIKSLDPNRVYITLGQTESIESEVE
                     NTKKEIKNLKETLKKNKKTLNEYKEAKKNGNESIQTLMQKELEEVKELSGYSTVTGPG
                     ITITMRDSERELKDGQNPNDLIIHDIDILRVLNDLKKAGARAISINGERVLATSKIKC
                     SGATITVNDTTYGQPFIIKAIGDIDLLSAAINSPESYAKSLKDIYGINIKVQENNGNK
                     VNLFAK"
     gene            complement(42971..43669)
                     /locus_tag="KOU88_001420"
     CDS             complement(42971..43669)
                     /locus_tag="KOU88_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF881 domain-containing protein"
                     /protein_id="HBK3211320.1"
                     /translation="MKKRFINKSIIIGSIVLGVLVSLQLKIINIENRGMTTFKRGEQL
                     TEELKSLKKEKENLQSEVNSVKKAIETYRGKNNEGEQDILKSEIEKYETLAGYTDVEG
                     TGIKIEINSTKDLGNSDKNDSILYNYDLLLSMINKLNSAQASAISINDQRIVSNTYMY
                     LKEDKLYMNDTVIKEPIIIKAIGDSDTLASALNIKYGIVWEIETYYNAKVKVTKEDNI
                     EINGHSDINKAEGK"
     gene            complement(43692..44432)
                     /locus_tag="KOU88_001421"
     CDS             complement(43692..44432)
                     /locus_tag="KOU88_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HBK3211321.1"
                     /translation="MKKRRKLNTNNVMIVLVFILMLSFCICIIVKSDLFDVKKIDVIG
                     NKRVTKSNIMKELNVNLNENIFAYNFKDMKNKLIKNPYIENVEIKRKLPNKIIISLKE
                     KEIFAVLKDEDNYCYIDKKGNLLEELRGSNESKKDLIVDVDYSIDDNKSIKFKNYKTK
                     ENVFKTLNYLKEEGIYRKINYVNLKKESNIEMLTRSNIKILLSNDDNLDYNISRVSKI
                     LIDLQNKNTNGGTINLNYGKLAVYSPEG"
     gene            complement(44702..45928)
                     /gene="murG"
                     /locus_tag="KOU88_001422"
     CDS             complement(44702..45928)
                     /gene="murG"
                     /locus_tag="KOU88_001422"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBK3211322.1"
                     /translation="MKVLLSGGGTGGHVYPAIAIANKIRDEHPDAEIIFVGTEKGIES
                     EIVPKYGFELKTVTVQGFKRKIDFDNVKRVFKLFKGLEQSRKIVKKFKPDIVIGTGGY
                     VSGPVLFNASMGKIPAIIHEQNSFPGVTNKILSKTVTKVLTSFEDSHKRFPEAAEDKL
                     VFTGNPVRKEILLSRKNIARKNLSISDEKRMVLCYGGSGGSRKINDAMRLVIKNMVNE
                     DIAFIFATGKSYYDEFMGSISDINLKPYQKVVPYLEDMANALAASDLVIGSAGAISLA
                     EITALGKPSIIIPKAYTAENHQEYNAKSIEKQGAGIAILEKNLTPESLNTAVFKLLGD
                     RELLVDMANASKTIGKPEAIDLIYDEIMKVYNSTQKSTSKKTKKEKVIKEVKEIKKET
                     TPSIEGQAKVIGIKKR"
     gene            complement(45946..47076)
                     /gene="spoVE"
                     /locus_tag="KOU88_001423"
     CDS             complement(45946..47076)
                     /gene="spoVE"
                     /locus_tag="KOU88_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein E"
                     /protein_id="HBK3211323.1"
                     /translation="MPKENLKKQIDIRMKTEFDGVVFYTTMLLVFVGIVMVFSASFIQ
                     SSFKHNDAYYFLKKNVIYAVLGFIVMIITSRIDYSFWKKNATAIGAIAVVLLLLVLTP
                     LGIEANGAKRWLGIGALTFQPAEIAKFATIILTAKLIEKNYDKIKSLTKGVVPLLVVP
                     GIFFALIILQPNLSTAGTVILVTFVMIFVAGMDMKIVFAMIGSGAALFAALVIAEPYR
                     LSRVTSFLDPFQDPLGKGYQVIQGLYALGSGGLFGLGLGKSKQKYFYIPEPQNDFIFA
                     IIGEELGLIGCIIVIMLFVVLVYRCVRIALKTSNVFACMVVIGIGAQIGIQAALNIAV
                     ATSSMPATGVALPFISYGGTSLTIFMGAVGIVLNISKHVKIN"
     gene            complement(47128..48483)
                     /locus_tag="KOU88_001424"
     CDS             complement(47128..48483)
                     /locus_tag="KOU88_001424"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBK3211324.1"
                     /translation="MDLKGKKVLLVGLAKTGISTIKHLDKLGASIIVNDIKDENKLRN
                     ILDELKSINDIKYILGHHPEDVDDIDMVVVSPGVPLDLPFILKLKNSGKYIIGEVELA
                     FKLSNNPIFIGITGTNGKTTTTSLVGEIFSRAKRDTYVVGNIGNPVIDTIETSSEESV
                     LVTELSSFQLESIDEFRPKVSAILNITEDHLNRHHTMEKYIEAKANIFMNQTVEDFCV
                     LNYDDEIVKSLADKCNAKVIYFSRTKKVNGGVYLENNDIIIDIDDKIKFLNKDDVSLP
                     GGHNLENCMAAIAIAYVCKIDLEVIKDVLMTFKGVEHRQEFVRNLDNVIYVNDSKGTN
                     PDSTIKAIQSYDRPIILIAGGMDKGSNFDELLETAKSYVKSLVLLGETASNIENCAKN
                     KGFNDIHIVKDMEEAVKTSYEISKSGDIVLLSPACASWDMYESFEVRGKDFKDNVNNL
                     K"
     gene            complement(48502..49470)
                     /locus_tag="KOU88_001425"
     CDS             complement(48502..49470)
                     /locus_tag="KOU88_001425"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBK3211325.1"
                     /translation="MMLGITELTYTALIAFLIVIIIGPIFIPMLRKFKFGQTVRDDGP
                     QTHLAKNGTPTMGGIIMIVAILITGLTRVKVSHDMAVGLICIAGFGFIGFLDDFIKIK
                     LKRSLGLKAYQKIILQVALSFYVAFYQYTSSSSASQLMIPFTDFVINVGILYIPIMMF
                     IIVAIVNAVNLTDGLDGLASGVTLIVSVFFMLFASSIAGNTEVAVLAAATVGACLGFL
                     GFNSYPARVFMGDTGSMALGGAVVAFSVLTNSVLIIPIIGGIYFAEALSVLIQVGYFK
                     ATRKRFFKMAPIHHHFEQCGWPETRVVFIFWIITVVLAWISIIAVF"
     gene            complement(49511..50884)
                     /locus_tag="KOU88_001426"
     CDS             complement(49511..50884)
                     /locus_tag="KOU88_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBK3211326.1"
                     /translation="MECLTIKELVLATNGKLIYGDYNDCVSDIVIDSREANAQNAFVA
                     IVGENLDGHTFMKSAYDSGCKTFIKNESNGIKLESSDINLIEVKDTSLALGDISKYYK
                     EKFDIPFIGVTGSVGKTTTRDMIYSAISAKLNILKNEKNLNNHFGVPLTLFNLNKEHE
                     CAVIEMGMSGFNEIKYLVDIVNPKIAVISNIGLSHVEKLGSQEGILKAKMEITSNFDE
                     TNTLIVNGDDKFLSTLKEKEHVYKLKTFGFNKNNDVYCESYTMEEDSLTFICVINGKK
                     EEIFIPTIGEHNIYNAMSAILVGLCLNISLDYIKKGLKNFKGTKMRLDIIKNEKLTII
                     NDSYNASPDSMDAALKILGRYKGRRVAILGDILEMGEISEYGHRLVGKSSMNNTDIII
                     TIGENSVFIGEEAKQLGFNSANIYHFENREDVFNKLNELVKTGDTILVKGSRGMRLEK
                     IVEYLNK"
     gene            complement(51051..53030)
                     /locus_tag="KOU88_001427"
     CDS             complement(51051..53030)
                     /locus_tag="KOU88_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein D"
                     /protein_id="HBK3211327.1"
                     /translation="MRKVKRISKKRLVLVLILACALFFCLVIRTGYLQLMKGNWLSTK
                     ALEQQTRDIPIEPKRGTIYDRNMKELAVSVTKYTVWCKPVEVEDKKEAAEKVAEILDE
                     DYKDIYALISKKNMALVKVKRWIDDDKASQIRDAKLSGIWVAEDNQRYYPYGNFAPYV
                     LGHTSSDATGISGVEMQYDKKLKGKPGKLIVSTDASGREIPQGMEKYYEPVQGNGLVL
                     SIDEVIQHYTEKAVQKAYELNNAKKVTAIAMNPKTGDILALASKPDYDPNDSRTPIYP
                     YYQEELEKYNDKDKIKGYYQMWRNPAVSDTYEPGSTFKLITSSSALEEGVIKDGEKFT
                     CTGSVTVGGRKIKCWRHYRPHGTQEFKQAVQNSCNPVFVELGSRLGVGKMYDYIESFG
                     LMDKTGIDLPGEAKGILYNEKNVGPVELATISFGQSISVTPIQLITAISSIANGGDLM
                     QPRVVKSYTDNKGNITETVKPKKVRSVISKETSKKMLEIAESVVTEGGGKIAYIPGYR
                     LGGKTGTAQKVIDGKYAPGKYICSFVGIAPCDDPQIVVLAIVDEPTGVSAFGSTTAGP
                     IVKEIMNDSLKYLGVKPVYKEEEKAEYEKKQVKVPDVRNLKIGDAVKALEDAKLKPDL
                     DADIELPEDTKVKDIFPKPGVKVNEDSSITLYFEN"
     gene            complement(53042..53389)
                     /locus_tag="KOU88_001428"
     CDS             complement(53042..53389)
                     /locus_tag="KOU88_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211328.1"
                     /translation="MKKNYKIHNLNEYKNKKKNNYKKRNKKKIGAKCILLIATFSVII
                     LNLCGYSKISEMKYDIYYLQKDLRKKEIVLEELKAKETEKTSIKEIELKAKELLNMDY
                     PKDGQIKYIDVDN"
     gene            complement(53870..54805)
                     /gene="rsmH"
                     /locus_tag="KOU88_001429"
     CDS             complement(53870..54805)
                     /gene="rsmH"
                     /locus_tag="KOU88_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBK3211329.1"
                     /translation="MEFHHVSVLLNECIENLNIKPDGVYVDCTMGGAGHSKEIVKKLS
                     DKGLFIGFDQDKNAISTAKERLSEYESRVKFVHSNFENIKEELEKIGVYKIDGVLADL
                     GVSSHQLDEADRGFSYMQDAPLDMRMDVRCEFSAYDVVNTYTEDELTKIIKDYGEDNW
                     AKRIAKFIVEERANKPIETTGELVDVIKKAIPKKARIDGPHPAKRTFQAIRIEVNNEL
                     GVITKMINDASSIMNEGGRICIITFHSLEDRIVKNAFKHLASDCICPQHLPICQCDKE
                     SEVKIITRKPILPSEEEIEVNPRSRSAKLRVAEKI"
     gene            complement(54835..55581)
                     /locus_tag="KOU88_001430"
     CDS             complement(54835..55581)
                     /locus_tag="KOU88_001430"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBK3211330.1"
                     /translation="MDRVAFTLFGIDIMWYGILMACGMILGTLIAIKEAKRVGIKEDD
                     VLNIAIIAIPVGLICARIYYVVFNWSYYAQNMSQIFNFRGGGLAIHGGLIGGILAGYI
                     YTKIKNINFLKMADTVILGMPLAQAIGRWGNFINGEAHGGATNLPWGIMVDGVKVHPT
                     FLYESIWDFGIFIVLLLFRKNKKYEGQVIVTYITLYSIGRFFIEGLRTDSLMLGPLRM
                     AQVISLIGVVGGIIAHVYLSKKNKNNISEE"
     gene            complement(55975..57261)
                     /locus_tag="KOU88_001431"
     CDS             complement(55975..57261)
                     /locus_tag="KOU88_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBK3211331.1"
                     /translation="MEKIVNDILKEEVYYEKLQNGLDVYFMPKRGFMKKYAILATNYG
                     SNDLEFVPIGEDKKIRVNEGIAHFLEHKMFEQPDGGDAFDKFSKLGVNANAFTNFTMT
                     AYLFSATENFYESLEHLIDYVQTPYFTDENVEKEKGIIAQEIKMYNDDPDWNVYFNCL
                     KAMYVNYPARIDIAGTVDSIYKITKEELYKCYNTFYNPGNMALFVVGDLDVEKVIDVT
                     KKSNNYKVDKLSKSIERFYPEEPEGVKEKEVIEKFPISMPMFNIGFKDSNVGLKGKEL
                     LRKEIVTDILVGMLFKKGSKLYEDLYMQGLINENFGAGFSSQVDYAFSIIAGDSKEPK
                     KVKEIILDYIEKSKKEGLSKEEFERTKKKKIGSFIKCFDSINFIGNSFISYVFKDINL
                     LEYLDVIKDITFEEVEERLKEHFKEEYCVISIVEPK"
     gene            complement(57276..58541)
                     /locus_tag="KOU88_001432"
     CDS             complement(57276..58541)
                     /locus_tag="KOU88_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBK3211332.1"
                     /translation="MVNTKKIINLGNNINLTLIKTEKFKSNLISLYVQRLLDEKETTK
                     NALIPSIIASGSAKYPSARAISNKLDDLYGSSMGADAVKRGERQVLSFKVINISEKYL
                     DESIFEEVVEFFNEVINNTLVVDGGFKEEYLNIEKENLREKIQSIINDKKEYAQDKCI
                     EAMCKGERYSVSEFGYEDEIDSITSRELYEHYKNILKTSPIDIVVEGNFDEDKVVDII
                     SKNLKFEREEIINIPRADFIKNVDEVKVIDEQMEITQGKLVMGYRANVDYADIDKYYA
                     LVVGSNVLGGGPHSKLFVNVREKESLCYYIFSSIEKYKSIMFISSGIETKDYDKAVEL
                     IKKQVESVKAGDISDEELENSKLALVNSMKSITDNIGGMSDFVFSQSMAKTNSEVQDI
                     ISSIEKVTKKDIVEAIKNIELDTVYFLRN"
     gene            58857..59954
                     /gene="ychF"
                     /locus_tag="KOU88_001433"
     CDS             58857..59954
                     /gene="ychF"
                     /locus_tag="KOU88_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBK3211333.1"
                     /translation="MKLGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGVVSV
                     PDERLNKLQELYNSEKIVPTAIEFCDIAGLVRGASKGEGLGNKFLSHIREVDAIVHVV
                     RCFEDENVVHVDGSVDPLRDIETINLELIFSDIEILERRINKTQKAAKADKTLGSELD
                     LLKSIMSTLEESKCVRTMEFTEDEQTFVNSLDLLTSKPVIYASNVSEDDLADNGENNK
                     YVQQVKAFAETEDAEVVVVCAQIEAEISELDSAEEKKEFLETLGLEQSGLDKLIKSSY
                     ALLGLISFLTAGPKEVRAWTIKVGSKAPQAGGKIHSDIERGFIRAETIAFNDLVEHGT
                     MAAAKEKGLVKLEGKEYIVKDGDVILFRFNV"
     gene            complement(60433..62712)
                     /locus_tag="KOU88_001434"
     CDS             complement(60433..62712)
                     /locus_tag="KOU88_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3211334.1"
                     /translation="MLSDAKNNRYGLSIIAVISILVITISCLIYGSRLNKTLGEETNQ
                     YLSEIANQSVNVLKKQINGDIKLLESISIFIEGEESFEVDNILSILKRQAINSSFKRM
                     GVILPNGTAYTTDGYIEDFSKRDYFLKSMQGEVVITGKLKDVIEDDKNTNSNINVYSV
                     PIYKDNEVKGVIFATHSTKLYEKILSVPTFNGKGYSYITRSNGDIVLNPSSKNANSTK
                     ENLFSYIGRSDSISKSSINNMKSNIKNFKSGSLSYSMFGKGYYLSYAPIGINDWYLFS
                     EVPKTAISEKSYAIIKLTLSACVVLIIIFTALTIYILFIHKKSKEKLEEFAFKDNVTG
                     IGNSNKFNLEGGKFLSSHEKKNLVLIYFDIDKFKLVNDRFGYEEGDRVLKEIAEIIKN
                     IFKEQSVFSRISNDNFAIIFEKKNNRESIIEICELIRKKLSMIKTSLGVELNLIPSIG
                     VYFVEEGETNISTCLDKAMIAKTTVKRKYLKVYEIYAENLKETLIEERDIEQEMHDAL
                     KNEQFKVYLQPKVDLSTTKIVGAEALVRWQHPKKGLISPGVFIPIFEKNGFITELDMF
                     VFTQVCKNFKRWENENFPTFPISINLSRVHLENPGFISELERITKEYEIEPNLIEIEL
                     TESAIFDNTKILFKIMQTLKSVGFKISMDDFGSGYSSLNMLKDMPIDVLKLDRQFFIT
                     VGNAKKSQIVVSSIVQMAKQLDIKVVSEGVETVEQAEFLRFIGCDMAQGFLFARPMPI
                     EEYEKLILDRYSLNRKETN"
     gene            complement(62983..64437)
                     /locus_tag="KOU88_001435"
     CDS             complement(62983..64437)
                     /locus_tag="KOU88_001435"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBK3211335.1"
                     /translation="MKLNDIIQGLDIINVKGELNIDINNVQYDSRKVTKGTLFICIKG
                     FVSDGHKYIKDAIEKGASAFLVEEDVAIKGCTFIKVKDTRKDMAKVADNFYNHPSQKF
                     NVIGVTGTNGKTSITTILNEILTLNKNKVGLIGTIKIFDGEKDIVSNSTTPESIDLQY
                     HFNNMLDNGCDYCAMEVSSHSLALNRVDETDFKLGIFTNLTPDHLDFHKDLEDYRKAK
                     EKLFFKTTMANIINIDDEGGKKIYENIKGINVPCYTYGVDTKADFMARDIKSDSDGVS
                     YRLITPSYEEVIFIPVPGMFTVYNTLAVIAACYVLGIPKPIYKEGLRLSNGVSGRFET
                     VPNDKGISVIVDYAHTPDALENVLKTTQQFAEGKIISVFGCGGDRDTEKRPLMGAIGQ
                     KYSDLCIITSDNPRTEEPEAIIKDILEGIDKKKENYHVVVDREQAIAEAISMAKKDDV
                     VIITGKGHETYQIIGKVKHHFDDKEVANECLSKM"
     gene            64601..65470
                     /locus_tag="KOU88_001436"
     CDS             64601..65470
                     /locus_tag="KOU88_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3211336.1"
                     /translation="MDNKIGYLNDNFKIFNIRDKKDIQFEYHNHDFNKIIIFINGNVT
                     YFVDGIPYKLKPWDILFISNNEIHKPVIDSNVFYERIAIWISPEFMKKNSDASSDLEK
                     CFKIATENKCNRLRLNMHDIESIKSFIEQINISESNTEFGNEILRNTLFIQLMIFLNR
                     IFLKNENMESTEDVFYDETIKKVLNYINSNIDDKLSIDSISSEFFISKYYLMRKFKSH
                     TGTSIHNYIVQKRLILAKSLITNGHLMSEVCNKCGFNDYSSFVRAFKKNYGVSPKNYI
                     NNKNPLDITLLDE"
     gene            complement(65683..67755)
                     /locus_tag="KOU88_001437"
     CDS             complement(65683..67755)
                     /locus_tag="KOU88_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK3211337.1"
                     /translation="MKKVFGVLQKVGKSLMLPVALLPAAGILLGVSNALAGDALLAHF
                     PALANPTFQLIISIMESSGQIIFNNLPLIFAVGVAVGLTEGEGVAALAAIVGFLILNT
                     SMGVMAGVTEDMVDNSMYANIVGIPTIQTGVFGGIIIGIVAAYLYKKFYKIELPQYLG
                     FFAGKRFVPIVTSLVAIAIGIILSFIWPPIQEGLLSFSKNVIEANQTLAAFMEGSLER
                     LLIPFGLHHVFHNPFWYQFGEYVNKAGELVMGDQKIFFAQLKDGVNFTAGTFMTGAFP
                     FMMFGLPAAALAMVHEAKPEKKKFVAGIMASAALTSFLTGITEPIEFAFLFVAPVLFA
                     IHCLFSGLSYAIMQLLGVKIGFTFSGGLIDFLLFGVLPNRTPWYLAILVGIGFAVLYY
                     SVFRFMIRKFNLKTPGREDESETNAEVIEMSKNELASEILIALGNKDNLKSLDACITR
                     LRLVVNDINKVDKEKLKSLGAAGVMVIGNNVQAIFGPKSDSIKSDIKDIIEGKTKVES
                     TVTKNVDKNKVKKNMEVANMENTLVEKIDSLTNGELLDIEEVPDSVFSSKLMGDGFAI
                     KSSDGLIYSPVDGTIGVIFPTKHAIIIKSQKSGVEILIHLGIETVNLEGNGFEVFVNV
                     GDEVKAGEKLVKMDLEYIEKNGLSTISPVVFTNLEQNQKLSIKKGVTTAKEENRVSIL
                     RDDIEKIG"
     gene            complement(68058..68900)
                     /locus_tag="KOU88_001438"
     CDS             complement(68058..68900)
                     /locus_tag="KOU88_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK3211338.1"
                     /translation="MIIQQIYNNNVVLVLDENIKKELILTGCGIGFQKKKGQEIDKSK
                     IERTFVIQDESFLDKISKLASQVDEKFFEVSTEIIAYAEENLNTKLYEYIYVALTDHI
                     AFAIKRYHENITIKNDLLHEIKRIHKKEYEIGKWAVDYINKEFDVKFPVDEAGFIAMH
                     IVNSNYKGSSKESLLITKIVKDILNIIRYYYRVEFKEDDINYDRLLTHLKFFAKRLVK
                     KEKINDTNNEIIDIIKVKYEKDYDCAYKIKTHVEKNYDYYVSQDELLYLTLHIKRVIS
                     VLNL"
     gene            complement(69161..71203)
                     /locus_tag="KOU88_001439"
     CDS             complement(69161..71203)
                     /locus_tag="KOU88_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBK3211339.1"
                     /translation="MSILVTLLGLLVCTTISTVFSKKWSNIPLAIYQIVLGIILSILP
                     FKFSFSFNPEIFVICIIAPLLFSEGQNVSRKELLELRKPILLLAFGLVLITVFAGGIF
                     IHFLIPGMPLSVSFALAAVISPTDLVAVKSITQGLNFPKNMMSILEGESLLNDAAGVV
                     AFKVAVLATVTGVFSIEEAGIQFMITAFGGIIVGSILGYIIIKIRLSLHKWNLEEIPM
                     VIVIQIMTPLFVYFVAEEIGVSGILAVVMAGIAHGIEKEHLQNTTTKLRIISDNTWYV
                     LEYVLNGFVFTLLGFLLPSIYTGLSSKNENMALELTFISTLIVLILFVIRFIWVYLWH
                     NSFIKPKKNPLNNFFVGFLGFKDEEVVKESISKCKYSLIVATCGVHGTFTLATALSIP
                     FYLADKDVFPMRDTVLFISSEVILISLVLATVLLPRLLKNNVQESEPLLSDKEAYKLI
                     LKEAILKLSNEKAQEVQPVIHDLNEQLVDSEKGILNTPDNKLISMMIAEADQQGLLAV
                     LKLLEDGKISDRAFKLYRFYITKSRKSVQKSIFKIVKLKISMWIINRKVKKEVKEKIT
                     KIVSENKEIIKEFHHAYALSTKTAISFINKNTDEDNRHEALIAIRFYNRYLNWITRKI
                     QNDDKFEARVEYYRVMAIQSQRDSVQQLVETKQISREVAKELLENILYDEMMMIES"
     gene            complement(71355..72326)
                     /locus_tag="KOU88_001440"
     CDS             complement(71355..72326)
                     /locus_tag="KOU88_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBK3211340.1"
                     /translation="MKKEESLLKVEGLKKYFEVKSGLFDKEIKCVKAVDGISFDLKKG
                     ETLAIVGESGCGKSTAGRTILRLIEKTEGKVEFNGVDIYKLEKEELRKLRPKMQMIFQ
                     DPYSSLNPRLNVEQIISEAVIEHNLVPKNEIKDNILNVLESCGLSKYHLNRKPGEFSG
                     GQRQRIGIARALALNPEFIVCDEPVSALDVSIQSQIINLLMDLQDKYKLSYLFISHDL
                     SVVNHIAHRVCVMYLGSIIEIATKGELYLHSQHPYTKALMSAVPIQDPTIKKNRIILK
                     GDIPSPTNPPSGCKFHTRCPYCKEICKKEIPVLKEISINHFVACHLV"
     gene            complement(72327..73304)
                     /locus_tag="KOU88_001441"
     CDS             complement(72327..73304)
                     /locus_tag="KOU88_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211341.1"
                     /translation="MSKALIEVKDLKVYFHTDKGIVKSVNEVNFNINEGETIGIVGES
                     GCGKSVTAMSLMKLLPTSKIEGGEIIFRGKDILKMNEDELMGIRGNEISMIFQEPMTS
                     LNPAFTIGSQIIEGIMIHQDLSKEEAKKKVIDMIKLVEIPRAEEIYNSYPHELSGGMR
                     QRIMIAMALSCNPKLLIADEPTTALDVTIQAQILDIMKNIKEKLNTSIMMITHDLGVV
                     AEMCDKVLVMYAGKIIEVAEVVELFKNPKHPYTIGLLKSKPALGKNKDKRLYSIPGQV
                     PNPIGMPDSCYFSDRCEKVCDKCRTQIPPLIELNSGHSIACWLYKKEEI"
     gene            73523..75082
                     /locus_tag="KOU88_001442"
     CDS             73523..75082
                     /locus_tag="KOU88_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3211342.1"
                     /translation="MKFKKLASLILVSSLMLTFTACASNDKDKSSGSKSGGTVVIPMA
                     SDPDIINGAFANVKEDSLASNIVYAPLYTYEKGNLVNYLAEKVDFKDSKELTIKLKSN
                     LKWHDGKPITAEDVLFTFNTVLDEKQNSPSRQYLLVGEKPVKVEKIDDLTVKITLPTA
                     SESFLYGISKISPIPKHVFEGESNIAKSEKNNNPVGSGAFKFKEWKKGESIVFEKNAD
                     YFGGEPKADSIALKIIPNEASQEAALNNGEISLMKTSAEGYEKAKSNSNLQTYTYSEE
                     RLNYIVFNQNISNMANKEVRQALSYALNRNEMIESAYGKEGSVPAKSILVPEADFYTE
                     EGVEEYDQDTNKAKDLLDKSGVKIDKLKIGYNTGRFGHKNYALVAQQELKKIGIEAEI
                     VPYESKAFFNILFSNSTECDMYVNGYAWGLEPNPYRGMFETGQYCNQTKYSNAKIDAL
                     WEKGFTELNKEKREEIYKQIQQDISKDAPIYTIDYEQNLMAAQKNLKGIKDAKPSPAI
                     LFEDWSKLYVE"
     gene            75188..76147
                     /locus_tag="KOU88_001443"
     CDS             75188..76147
                     /locus_tag="KOU88_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211343.1"
                     /translation="MLKLILNRVKVLIPMLILISILSFGLLELAPGDPADAYINPLMS
                     SQDIENIRVNMGLDKPVYIRYLNWLKNTLSGNLGISYINHMPVTEQIMEKMGNTFILM
                     GTSLIFSILVAIPLGIFLAVNKNSITSKVSSVFNYIGVSIPSFWIGMILISIFSVKLN
                     IFPSGGMHTIGNDSIGDLVKHLVLPVITLGLYNTAIFTNYVEASVNEQLKKQYVITAR
                     AKGLSEKVILFKHVLKNSLTSLVTILGMSIQKLVTGAFVTEVVFSWPGMGRLMIDSIF
                     SRDYTVIMAITMLSALFLILGNLVADILYLLIDPKIKSSKGGF"
     gene            76150..76962
                     /locus_tag="KOU88_001444"
     CDS             76150..76962
                     /locus_tag="KOU88_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211344.1"
                     /translation="MFTSILKKLKKDKSFAFACITLSIIIILIITSFILNIDSNAIDT
                     TSKLQEPSLKHIFGTDELGRDYFSRALYGGRISLSVGILSMLISVVFGTAVGVISGYI
                     GGKLDQFLMRLVDMLMSIPSFLVLIVLNTYLTPKVSTIILIIGFLSWMEVSRIVRGET
                     LKIKENEYCLAAKATGIKTRNILLRHIVLNLKETIVVAGSLNIANAILTESALSFLGL
                     GIQLPLASWGNMLQDAQRHIFDKLYLAVFPGLLIFLTVMSLTIISKKFSSNT"
     gene            complement(77178..78080)
                     /locus_tag="KOU88_001445"
     CDS             complement(77178..78080)
                     /locus_tag="KOU88_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3211345.1"
                     /translation="MDIKQLKYFVEIVKSGFNLSIASKTLHISQPALSQIIKNFEESE
                     DVYLFERYKGRLNGLTPAGERFYVNAEHIINEYKNMMEDLREDSVQFKGKVRIGIPPL
                     ILGIVFSDVVAQLVANNPDIEFDIVEKGAYDLNRMLILQELDYAVLLHPHKIDKSVVT
                     EHVLQEDELTAFLNINHPLAKKDKIDWNDLNEQLLAIFNPTFMIHHKLMQKFTDENVK
                     LKRYIMSGSWDFLLLSTTNSDFITILPSPVHDFFENSKIIEKPFNHPITWKVILCRPK
                     KERYSHVDQHVFKFIIDFFSKKNS"
     gene            78435..79613
                     /locus_tag="KOU88_001446"
     CDS             78435..79613
                     /locus_tag="KOU88_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBK3211346.1"
                     /translation="MKDVVIVSAVRTPIGSFGGVFKNTSAVQLGTIAVKEAISRVGLN
                     LSEIDEVIIGNVLQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSI
                     TSGENDVVIAGGTENMSQAPYIVPTARFGSKMGDITMVDSMLTDGLIDAFNQYHMGIT
                     AENIATKFEFTREMQDKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDE
                     YPKLGMTFEGLAKLKPAFKKDGTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKI
                     KSYASAGVEPEVMGTGPIPATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQID
                     SSKLNVNGGAIALGHPIGASGARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR
                     "
     gene            79622..80278
                     /locus_tag="KOU88_001447"
     CDS             79622..80278
                     /locus_tag="KOU88_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase subunit A"
                     /protein_id="HBK3211347.1"
                     /translation="MNKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLCSKNIK
                     DLTLICNDTGFIDKGVGKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTL
                     AEQIRAAGYGLGGILTPTGIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDK
                     AGNLVYKGSMNNFNNLMASAAKITIVEADEIVEIGDIDPNEVNTPGIFVNYIVEGGNL
                     "
     gene            80278..80943
                     /locus_tag="KOU88_001448"
     CDS             80278..80943
                     /locus_tag="KOU88_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="HBK3211348.1"
                     /translation="MDKLEMQEYIANRVSKELKDGAVVNLGIGLPTKVANYIPDNVNV
                     ILQSENGFLGLGSAEDGNSSDETIVNAGGQPVTILPGGCFFDSATSFGIIRGGHVDIT
                     VLGALQVDKYGNIANYMIPGKMVPGMGGAMDLVTGAKKVIVAMEHTSKGSAKILNNCT
                     LPLTATNAVDLIVTEMGVMEVTSDGILLKEINPAFTLDDVISATEAPLILSDSLNGKI
                     SVV"
     gene            81048..81824
                     /locus_tag="KOU88_001449"
     CDS             81048..81824
                     /locus_tag="KOU88_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyrate dehydrogenase"
                     /protein_id="HBK3211349.1"
                     /translation="MVKDKVVFVTGAASGIGKQIAESFLKNGAKVMFSDINQEALNNT
                     ITELQKKGYDCMSVKCDVTKEEEINHAIDKTVEKYGRLDILINNAGLQHVSMIEDFPT
                     DKFEFMIKIMLTAPFIATKKAFPIMKKQGFGRIINMASINGVIGFAGKAAYNSAKHGL
                     IGLTKVAALEAADSGITVNALCPGYVDTPLVRGQFNDLSKTRNIPLENVLEEVLYPLV
                     PQKRLLDVQEIADYAMFLASDNAKGITGQACLLDGGYTAQ"
     gene            81886..83220
                     /locus_tag="KOU88_001450"
     CDS             81886..83220
                     /locus_tag="KOU88_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBK3211350.1"
                     /translation="MSIIAPIGIIIGIIAIIYFSVKEIHITIAAPIATLIVVILNKMD
                     VVTSMLGADKNNYMGALGNYIMSYFAIFLLGSILAKFMEESGATVSIADFILNKFGSN
                     HPYRVLVAIFIVSFILTYGGISLFVVMFAVIPLARTLFKKLDISWNLIQIPLWLGIAT
                     ITMTIIPGTPAIQNVIPIQYLNTSLTAATIPSIVGSIGCATFGLVYMKYALNKSIRKG
                     ETYATYTSELEEESLDRELPGFFASIFPLLALVIIAITGSTFGSEFMKKNVIYIALIV
                     AILLSAFLFHKFLSSKIQTLSIGASGSIGPIFATSSAVAFGAVIMAAPGFDVFSKLIM
                     SIPGSPLISLTVLTSTMSAITGSSSGALGIVMPNFADYYLSTGLNPELIHRVATIASN
                     ILTIVPQSGVFLTFLSLSKLTHKTGFKETFIVVAVGSLIAEIIVITLGLLMY"
     gene            83716..84561
                     /locus_tag="KOU88_001451"
     CDS             83716..84561
                     /locus_tag="KOU88_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein"
                     /protein_id="HBK3211351.1"
                     /translation="MMRRNIPTKLKTILALGVLTLATASSAVTASASSLENNVNISNK
                     SLVYSNTKYKFSAKPNCSVKPELKPDKDNSCKDKNHNDKNCNNTNKPEDNNNSDSTNK
                     PDNNKPESNKPEDNNNSGSTNKPESNKPEDNNNSDSTNKPDDNNNSGSTSESFSAYQK
                     EVVDLVNIERAKAGLNPLTLDSSISNVATKKSQDMIDNNYFSHNSPTYGSPFDMLKKF
                     GISYKTAGENIAMGQKTPKEVVNAWMNSEGHRKNIMNPNFSKIGVGVAQKSGGSIYWT
                     QIFVG"
     gene            complement(84953..88492)
                     /gene="nifJ"
                     /locus_tag="KOU88_001452"
     CDS             complement(84953..88492)
                     /gene="nifJ"
                     /locus_tag="KOU88_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBK3211352.1"
                     /translation="MAKFMKTLDGNTAAAHVAYAFTDVAAIYPITPSSTMAEVVDEWA
                     SQGRKNIFGQTVNVVEMQSEAGASGTFHGSLQGGALTSTFTASQGLLLMIPNMYKVAG
                     ELLPGVFHVSARALASQALSIFGDHQDVMAARQTGCVLLASGSVQEVADIAPVAHLAA
                     IEGRLPFIHFFDGFRTSHEIQKVELLENEDYASLLNFEAVQAFRDNALSPNHPVARGT
                     AQNPDIYFQTREASNKYYQNIVGIVEKYMEKMSNLTGRKHSLFDYYGAEDAKYVLIAM
                     GSVTETIEETIDYLNAKGEKYGLVKVHLYRPFSMKHFLDAMPSTVERICVLDRTKEPG
                     STGEPLYLDVRDVFYGKENAPMIIGGRYGLGSKDTTPSDIKTVFDNLVSEQPKNGFTV
                     GIVDDVTNTSLTPSEPIKIASKGTIRCKFWGLGSDGTVGANKQAIKIIGDHTEKYAQA
                     YFDYDSKKSGGITMSHLRFGDTPIRATYLIDEADYIACHKQSYVYQYDLLKGLKKGGT
                     FVLNTIWDQAGLEEHLPAHMKQYIAKNDIKFYTVNAVKLGQEIGLGNRINMIMQSAFF
                     KLAEIIPEEDAVKYLKDSIVKAYGKKGEKIVNMNYAAVDAGINALVKVEVPASWENAV
                     DADKGEVKEPEFIKNILRPMTAQEGNNLPVSTFNGIEDGTFPCGTAAYEKRGIAVDVP
                     EWIIDNCIQCNQCSFICPHSCIRPVLVTEEELANAPEGFEAKKALGKGLEGLKYRMQL
                     SPLDCTGCGNCADICPAKEKALVMKPIDTQLDTELDNWAFAVNPDEVAPKGDVMPVNT
                     VKGSQFRQPLMEFSGACAGCGETAYIKVVTQLYGDRMMIANATGCSSIWGASAPSIPY
                     TCNHEGKGPSWANSLFEDNAEYGFGMYTAVKQIRNKIVDAMTELVSMGICEDAKAVFT
                     EWLDSRNDGEASKVASAKVVELLEKPACDCTDEKAKELVKAIKDRKDYLVKRSQWILG
                     GDGWAYDIGYGGLDHVLASGEDVNVLVFDTEVYSNTGGQASKATPAAAMAKFAASGKK
                     SRKKDLGMMAMTYGNVYVAQVAMGADKNQFIKAVIEAEKHDGPSLIIAYAPCINHGLK
                     EGMGRTVANEAQAVACGYWHLYRFNPEVKAEGKNPFTLDSKEPTASFKDFILAQVRYS
                     AIAKQFPEEADGLFAKAEADAKERYEGYKKLAE"
     gene            complement(89010..89579)
                     /locus_tag="KOU88_001453"
     CDS             complement(89010..89579)
                     /locus_tag="KOU88_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBK3211353.1"
                     /translation="MKLPIALSNKHAHLSQADIDVLFGAGHELTKFKPLSQPGQYACE
                     EKVDLVGPKGTLKGVRVLGPARAHTQVEISLADGFPLGVKAPIKESGDIAGTPGVKLV
                     GPAGEVEMKEGVIVASRHIHMSNEDAAKFGVTDKQIVKVKTSGPRALVFENVLVRASD
                     SFNLEMHVDMEEGNAAGVKNGDLVELIVD"
     gene            complement(89651..90259)
                     /locus_tag="KOU88_001454"
     CDS             complement(89651..90259)
                     /locus_tag="KOU88_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3211354.1"
                     /translation="MDSNDKKGLKSPEIIIINGSPRINKNCSFIANEVKAMLEECGLS
                     CKIFNIYNMDIEYCTACGFCEKTGYCKFNDDMKPLYKMFDDSKGTIVISPVHFDSISA
                     KLKTVVDRTQAIYASKYVLNKPSIDRSKKRIGMYIAVGGSKSYDSQFKGGQIVMDFFF
                     KSINTKLLHNIYLNNTDDVSYIDNQEFKDIIYKNLKIYIDSI"
     gene            complement(90267..92030)
                     /locus_tag="KOU88_001455"
     CDS             complement(90267..92030)
                     /locus_tag="KOU88_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="HBK3211355.1"
                     /translation="MTNGSYKMKNLVEISAMVTESTDFFNIKDDIIEKMLEVVHPTKA
                     CVNLFYKNDSKYAYLVCSQTLEYVPQIFPINSLKGAKIDFDTYPEYIHEAVNEKKIIY
                     VENVFEDSRAEGERDLAKAEGYIGRIVFPFIINNVVVGFMTCFLKEDDYITEQDIDFI
                     SSVASLLSLSIEITNKNNNVQILIDKLRGSISAINEATKKLYLNKSIDGFLENLSKQA
                     CNITNSKEALIIINSHHNKDAIVSCYNVEQKKKTNLYPMIDMFLKKESLGGYLNNLKP
                     CSKKGINLESYIYYKLQDKNDTIGCIVCANSKNYTSDDLNILSILSKQVSVGMQLYEH
                     NEKEVKHKVLENELNILNKQQQLIMDKGKMDCNDEKELYFYHKPARVVGGDFYYATKV
                     DDEHIVYIVADVMGHGMVSNYVVAMIKGAFKVLCNQYNTPREIMTNLNRMLYDEFDKM
                     GVFTTCLIGIIDTKENMITVSNAGHYSPVVVKKDGTIENNLNCKKGIPIGIMEDATYE
                     NNTLSMEDYAMVCMYTDGILEIKNSSKEEYGINRLENFLKENFRLNQQLIVENLKLDL
                     KNFSSKDNYDDDILIVMLKDR"
     gene            complement(92073..92540)
                     /locus_tag="KOU88_001456"
     CDS             complement(92073..92540)
                     /locus_tag="KOU88_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211356.1"
                     /translation="MKMLNGIIKLFYSEIVKTKINNLDSSGYSLRDECKEIRNITLKI
                     DSVFFKLLKLAFGSILLMVAFNLNMVLGIGVFLVGVVYILYKRNMEEQVKEHINNVKN
                     NIDISKITFMDEKGRTGLNALITLLLIGLLTGFNWILVASFVVVFVFTIKNVC"
BASE COUNT        30173 a        16036 c        10520 g        35958 t
ORIGIN      
        1 atatagagaa cttcgaaatg ctatatcaaa aaataaaata gataaaccta tgtatgtata
       61 ttattttgaa tctccagaaa aatttgcatt taataaagta ataagaacaa aaaatcaaaa
      121 cgaaatttca ttagaaaaat ttaatgagtt taaagaaact atacaagaca aattattacc
      181 atacaacaga taattcaact gctgttcaaa atagcaatgg ataatcatga aatactggat
      241 taagtataaa caaaggagaa tctgcatata taaatgcaaa tattagatac tacaacacag
      301 gtactgcacc tatgtacaaa gtgacaccaa caacaaattt agtgttagat ggagatgcat
      361 tatcaactat caaagcacaa gaaaatcaaa ttggcaataa tctatctcct ggaaatactt
      421 atctcaaaaa aggattttca cctatggctc ttaacacaat gtatcaattt agttctagac
      481 tgattcctat aaattataat taattaaaaa aattagatga tggaaagcaa attaaattag
      541 aaacaacaca agtaagtgga aattttggta caaaaaatgg ttctggacaa atagtaacag
      601 aatgaaatag ttggtaagac gatataggtc aaattgacag tatttctgta tctattatat
      661 tagatacaga aaatgaatct tacaaaagaa gaattactgc taaaagttta caggtcccag
      721 aagataaaac acctgaactt acaattggag aagcaattga aaaaactttt ggcactacta
      781 aaaaagatgg tttgttatat tttaataata taccaataga tgaaagttgt gttgaactca
      841 tatttgatga taatataggc aataagatta aagacagttt aaaaactttg tctgataaac
      901 aaatatgtaa tgttaaactt gaaagaggaa tgaatatact tataaaaaca ccaacttact
      961 ttactaattt tgatgattac aataattacc ctagtatatg gagtaatgtt aatactacaa
     1021 atcaagatgg tttaaaaggc tcagcaaata gattaaatgg tgagacgaag attaaaatac
     1081 ctatgtctga actaaaacct tataaacgtt atgtttttag taaaattcaa aaaatccttt
     1141 aacatataat tcaataattg taaatataaa agtaaaagaa gaaaaaacgg attatttggt
     1201 actagaacaa ggatatacaa aatttagtta tgaatttgaa actactgaaa aagattcttc
     1261 taatataaat atagcattaa ttgatagtga tacaatatac ttagataact tatctattac
     1321 agagctaaat agtactcctg aaatacttga tgaaccagaa gttaaaattc caactgttca
     1381 agaaataata gttacacata aaatatattc tgcagatttt aaatttaatc caagtacaat
     1441 aaaggcttat ataaatggta tgtattttac accaacataa actaataaag aagctctcga
     1501 ttatgtccaa aaatatagag ttgaagctac tttacaatat tttggattta aagatattga
     1561 aactaaagat aaagaattgc gtaattattt aggagataca aatcaaccta aaactgattg
     1621 tgttaatctt aggagttatt ttacaggtgg agaaaatatt atgacataca agaaattaag
     1681 aatatataca attactcaag atgatagaga gttattggtt cttagtgttg attagtatca
     1741 aatgatttaa atttatcccc acaatacaat atgtatttac cttataaagt attaaaaaat
     1801 taactttata aggtattttt tatttaaata ttatcttctt ctaatatatt cttttttaga
     1861 actatattgt attaaaaaga taattatctg tatcatatca cctatatata aacataaatt
     1921 catttaatta tataaattta aaaaatattt ttttgatata ttattgacaa ttttcattat
     1981 aagagttaaa attaactcat aaattacata ttgggtataa aatacaatgt atgttagaag
     2041 ttgtttcaga aggctatggt tttctgattt ttttatgctc agtagtgata tgcaaaaaag
     2101 acaaagttga catcagttaa cttttacctt tattctactt tccccaaagt aagaataatc
     2161 taaccccttt gagatgagca aaagctcatc tttttttatt atcaaaagat gctgtctcaa
     2221 aatagagata atcctctttt tcattgttga aatgattaaa atatatttta tttcatacaa
     2281 aaaagagtgc ctcatgaaca aaagttcact ttgagactct ctctttcata tcatatacct
     2341 ttttaataac tttaaaattt atttatcaag taaagatagc taataattag tatcttctct
     2401 ctataaatcc aactttttta taaacttttc taagagtttt tctagcttgt ttttcggctt
     2461 tttctgctcc catactatat attttttcta aataatcttt attattaaga aggtcaacat
     2521 atttttctct tataggtctt aaagcttctg atactacttc agccacatct tctttaaata
     2581 tgccataacc ctttccttca tacatgttta caatctcttc tacactcttt ttacttaaat
     2641 tagaatatat atcaattaga tttttaatac ctggttgttc atcattgtat tttacaacac
     2701 ctaaagaatc agtaacactt ctttttatct ttctctttat agaatctgaa tcatctgcta
     2761 atagtataaa tgcattttca tttgaatcgg atttactcat ttttttagtt ggctcttgca
     2821 aactcatcac tcttgctcca ccttttgggt agtatccttc tggaactaca aaagtaggtg
     2881 aaaatctatt attaaatcta tttgctaaat cacgagctaa ttctaaatgt tgtttttggt
     2941 catctccaac tggaactagg tcagtttgat acaacaatat gtcagcagcc ataagaactg
     3001 gatatgtgaa taaacctgca tttagatttg cttcactctt ttgtgattta tctttgaatt
     3061 gagtcattct acttaattca cccatataag tcatagtatt caatacccac ataagttcaa
     3121 catgctcttt gacatgtgat tgtataaata tagtattttt ttctgggtct aatccacaag
     3181 ctatatattg agcaagtaat tctatagtat tggctcttaa aactttaggg tcttgaggta
     3241 ctgttattgc atgcaaatca actatactat aataacaatc ataattgtct tgaagttcag
     3301 tccagttttt tatagctcct aaataatttc ctaaagtcat tttgcctgat ggctgtgcac
     3361 cacttaatat aacttttttt tcactcattt ttttgtacct ccttatatat ttatattgat
     3421 tttaacatat ttaaaactat gtctttagag ttattggcag catcatgtac aaatacatca
     3481 taagtaacat cagcacttcc atctgcctta tcagacattg ctcttattat tacaaatgga
     3541 gtattattta aatagcatac atgagctata gctccacctt ccatttctcc acaatatcca
     3601 ccaaaatcat ttaataattc ttcttttaat tctttagaat ttataaattt atctcctgta
     3661 actactcttc cttttaatac tttatgagtc tttacttctt ccacagaaga tttgtaagca
     3721 gcatctataa gtctttcatc tgctttaaat acagaagtct tcattcttgg tataactccc
     3781 ttagggtctc caaatgctgt agtgtctaca tcatactgta tagcatcagt tgatattact
     3841 atatcattaa catcaagttt ttcgtttaaa gctcctgcaa cacctgtatt aacaatagca
     3901 tcaaccttaa attcgcttat tagtatctgg gcacaaagag cagagttaac cttacctatg
     3961 ccacacttta ctaacactac attcttacct tccaaaattc ccttataaaa ttctaagcta
     4021 gcttttttta tagtctctct aatatccatt aaatcaacta aaatactaac ttcttcatcc
     4081 attgcaccta taattcctat tacgttcatt tttcctccta aattttctat attaaaaaat
     4141 ccgtcctaaa tcaataggac ggatatattt tccgtggtac cacctaaatt tatatacact
     4201 caaaattgaa tatatatatc ttaatatatg ctataacgtg catacacgat atcaaatact
     4261 ctgtaatctt aaattacatt tcattttact cctcaaagac ccattcaata aatacttttt
     4321 attaagttct cagcatcctt aattctctgt gcaaaaatat atttatttac tatttcttat
     4381 ctcaggattt aatttattaa tttctttatt ttataatatt ccttacacta taaattgtca
     4441 actatatatt ataatatcca aaagaaattt ttaaaataca ttttatttag ctgttttctt
     4501 ttcatatcta ttccataacc atagaccaga taatataact agaagacctc caccaatcat
     4561 ctctatctca tatataacat tttcagcaaa tgtaggcata actggtgctg cagataataa
     4621 tatacccact acagttacaa ctaaaaccat ttttgctaaa cctaggcaag tacttgttga
     4681 ttttgccata gtataaggtc taatttcatc tggtctctct tttcttagtt taatataaga
     4741 agcatataac aatacatatg ggaataatgc agttaatgct gtcatagtta caagaacatt
     4801 gtatatagca tcaacagaag gcattaatgt agtcaccaat agtattatag taactattat
     4861 tgcttgaagt ataactgctt tagaaggtat cttgtgttca tttacctcta ctaaactatc
     4921 tggaaatatt ccttttttaa cactaccaaa taacattttt attggtgatg ctatgtaaag
     4981 aactattgct cctaatactg aaaaagctat accaaaagct attaattgaa ccaaccaaga
     5041 accaattcct aaagacgcac aaacagcaga aagtgcatct aatacacctt tagaagcagt
     5101 aatttggtct ggtggtatta tcattgttat tgcaattgaa cctaatacat ataatgaagc
     5161 tactattcca gctgatatta atattgcctt agggaagttc ttttcaggct tatctatttc
     5221 tgttatgaag ttagcagcag tctctgctcc tgctaaacca aacattatag ctgatatagc
     5281 aacaaatgca tccatattaa gttttggagt cattgaagct attgtgtatg tagaagctat
     5341 atcatgtttt ttcaacacaa atactgctac aaatgaaaat attataagta tagcacttgg
     5401 tattgttgaa cctaatgcac ctgtattagt aaatattttt gtaaaactta ttcctttagt
     5461 tgctataaga gataatgccc agaatattat taaagataat ataagtacaa acatcttatt
     5521 atcagcaagg gctggatttc ctattgtata agaaacattt actgctaaga aagttaaaaa
     5581 tgaagaatac caaaatattt tagctgtcca gtttaaccaa gaaactaaaa atccatactt
     5641 ttctccaaag gcttccttaa cccaatcgta aagacctcca tcaccttttt gatatgtaga
     5701 agctaattca gcacaaatta aagctcctgg tacaaagtat ataaatgaga ataataacca
     5761 cataggtatt gcacctaatc ctaaaccaaa gcttgatgct gtagatttag ctatccatct
     5821 tataccatat aaagctgata cattcataaa taccaaactc cataggccta tttttttctt
     5881 ttccatccta atttaatttc ccctctctat taattatttt aaatttaatt tcaaaattaa
     5941 taaaatagat tcattattat taaactgata tttttcaaaa tatttgcata ttcaaaaaca
     6001 gttttaataa taaaccttaa atactttgaa atcaaatctt attaaaaatg ataaatttaa
     6061 aagttttacc actttaattc taatgatact aaatttttaa aattgtttca atattatttt
     6121 attataaaat tttatttatt atttttcatt agtatataaa aagataaaat acataacttt
     6181 atagacttaa tttattactt ttatagaatt ttcacaataa aaagtcattt tacttccgta
     6241 tttaatgcaa aagtagaaat taaacttaat ataaaaaata tataacaaat tttttttata
     6301 tttctagaag aaaagtatac tcttttttgt ttaataatgc taaaattgat ttgtattgaa
     6361 ttttgattag gaggaaatta ttatgaaagc tcaaagatta aatgctgtac ttgaacaaat
     6421 gaaaaaagat gatatttctc aaatgttagt aagtgaccct acttctatat tttatcttac
     6481 aggagtacta atccatccag gcgaaagact attagcatta tacttaaatt taaatggcaa
     6541 taataaatta tttataaatg aattattccc agtttcagaa gatttaggtg ttgaaatggt
     6601 ttggtttaat gatactcaaa atccagtaga aataataact gaacatatag acaaaaatgc
     6661 tactatgggt gttgataaaa actggccagc tagattctta ttaaacttaa tagaattagg
     6721 tggaggaagt aagtttgtaa attcatctta tataatagat actttaagaa tgtgtaaaga
     6781 tgaagaagaa aaagagttaa tgagaatagc ttcaaaatta aatgacaagg ctatggaaca
     6841 acttaaagct actgtttctg gtgaacttac agaaaaacaa cttgttggta aattatctaa
     6901 aatatatgaa gacctaggta ctgatggatt ttcatttgac cctattatag gttttggacc
     6961 taatggagct aatccacatg gtgaacctgg aaatgcactt gtgaaaccag gagatgcaat
     7021 aatcttagat ataggttgta taaaagataa ctattgtgct gatatgacaa gaactgtatt
     7081 ctataaagaa atacctgaaa aaggtagaga aatatttgaa atagttcttg aagctaataa
     7141 gagagctgaa gctattgtaa aaccaggtgt tagattctgt gatatagatg ctgctgctcg
     7201 tgactacata actgaaaagg gatatggaca gtacttcact catagaactg gtcactctat
     7261 aggacttgaa gttcatgata aaggagatgt atcttctata aatacagata ctgtacaacc
     7321 aggaatgata ttctctatag agccaggtat atatttacca ggtgagttcg gagttagaat
     7381 agaagattta gtacttgtta ctgaagatgg ttgtgagata ttaaacaaac atgacaaaga
     7441 aatatgtgta gttggttaat tctaaaatca atttgataaa attaaaaagc catataaaaa
     7501 tgttttaaac atttttatat ggctttaatt tctcaatcta tgatttattt caatccatta
     7561 tttatattgc agttattaag attgcaccct ttgaagtata tgtccccatc actgaaccaa
     7621 tttcacagat tacaacatct ttgtatttta catccttttc cataacttcc cttacctttt
     7681 gagccttttc tgggcaatta gcatgtccta taaataaaac cttttcttct ttatctttaa
     7741 tttttgactc tactaaagta atcagctttt tcaaactgtt tccttcacct cttgccttat
     7801 ctataggagt tacaacgcca tctgcaactt gtattatcgc cttaaaattt aaggtattta
     7861 taatttttcc tgctattgga tttattctac cacccttaat agcattttct aaagtttcaa
     7921 gtgttccaaa aaatggagga ttatctttat atttatttat tattgaaaca atctcttcaa
     7981 tttcttttcc ttcttttatt aatattgctg cttttaacac taattgtcct attccaattg
     8041 acccactaag tgaatctata acctcaactt tcttgttatt tccttccttt tcaaacatat
     8101 cttttgctaa aagtgcacta ttataagtcc cagataatcc tgaacttata ttaatcacta
     8161 atacactttc ttcctgacaa tggtatgctt ctaaaaattt atcaggagaa ggacatgatg
     8221 tttttggtag tactttactc tcactcattt ttctatagaa agtttcatta tctatttcct
     8281 ttccagatat ataactttct tctccaaaag atacatttaa accaacaact tctatgttgt
     8341 atttttctat tatatcatca ggtaagtcac atgcactgtc cactatcaat tttattttat
     8401 ccatattaac ctcactataa gatattattt tatttattca gtcggtcgta cgaccgattt
     8461 aattattatt ttatatattg aatgaaaaaa agtcaataga tatagattct cgctttattg
     8521 acaataaata tccataagct tataatgtta ttaatttgtt ataaatatac atggaaaggt
     8581 aggttttatg aaaacaaata atatgaaaca ggctatttta tcatctgcaa ccaatttaat
     8641 agccaaaaat ggagttcaaa atactagcct tgctgatatt gcaaaagatg taaatataag
     8701 taaaggtact ttgtattatc actacgcatc taaagatgat attatatatg atattgcgga
     8761 tactcattta gaagttataa ctagtgctat actaaactgt gtaaaaaatg tcaaatcaaa
     8821 aaattctcaa atagaaatgg ttaacttaat cttagagaaa atatctacta tagaaagtcg
     8881 tggtagggta catatgtatc ttatttgtga ggcaattact tcaaataatg atttaaagga
     8941 aagaataaga ttaaaatata ttgaatggag aactactctt aaatctgaaa ttgttgaatc
     9001 actagaaaaa tataatagta gcgaaaatga acaggatgct gaatcatttt cttttttact
     9061 catgtcaata gttgatggtt tagttgtcca aagtttatta aaaacagaaa aaatacctta
     9121 tgaaaatata gcttcttttt tagttaatca ttggatttaa acttaatact tagataatta
     9181 ataaaagtga actatttaag ttatctactt taacagttca ctttcttatt tattctcaat
     9241 aatttttact taaaacattc aatttttatt taaaccttca tggaatcaca aaataaaaat
     9301 ctcttataaa tttaaaatgt ttttatttat gttcatgtgt atgcccatct gaatgttcat
     9361 gaccatgtgt atgtgtatgc tcatggctat gctcatgatt acctgaaaaa ccatcatcat
     9421 gattatggtc gtgacctaca ccatttacat gctcatgttc atgcccatga ctgtgagaat
     9481 gttgatgtga atgttcatgg ttatctcctc cacagcatcc ttctcctcca gtcccacaac
     9541 acccacttgt atgtggatta tgatgatttc ttactacaaa tctctctctt aacataattc
     9601 ttatacctcc tagtatatta ttgagtactt catgtacccc attaactaca gtatacatct
     9661 aactaggtat aatctcaata catatggcat tttttaacat atataatctt aaagaaattt
     9721 atccttaaaa cctccacctt ttacttcttc aacgttattg acagaaataa aagcttcact
     9781 atccatatca taaattaaat ctttaaattt acctatttca tttgcagata ttatacaata
     9841 aatcatcttt ttcttatttt gtgtatatgc accttctgcc tccaaaaaag tgactcctct
     9901 acccatttta ttcattatca ctttggatat ttcatcatat ttatttgata ttaaaagtat
     9961 agattttttt ctatcaaagc aatcttttcc tatatccata gtaaaagaaa ttatatacat
    10021 tgtaattaaa gtgtacatca ccaatttagc tccaaataaa aaagctcctg cacatactac
    10081 aaaaaaatta ataaataaaa atgtattttt cataggtata tcatactttc ttttcattat
    10141 ggctgctatt atatcaagtc ctccagcagt agctcttgct ttaaaagtta accccatacc
    10201 tataccagtt aatgcaccac cataaataca ctgtagcata gtatcatcta ttgggaaata
    10261 tttagcaata tcttgtgtta gccccagtgc tagagaaaat agtaacatat tgacaaaact
    10321 tattagcaaa aatttattat caaaatactt tctagctata ataaatattg gtatgttcat
    10381 caagaaactt gatattccct gatttatacc aaataatttg tataatataa cacaaattcc
    10441 agctactcct ccacttaata acttggctgg tgctagatat aaatttattc ctaaggttga
    10501 tagaatcata cccaatataa taagacaata ttgtaaaaat atgttattat caatacttag
    10561 ctttttactt tcaccataca tcaaaacgca cccctttgca taataaataa accaccctgc
    10621 agaacacacg ataaatttac aaataaattt atcagaagta gcttactaaa aatattattc
    10681 atcctcactt aaacgtttat tcattaatat tctatcacat gacataaata atttatatga
    10741 tttatataga tttatttatt gtaaattttg gaatattaaa atattttatt gaatagataa
    10801 ttatattaca taaaaaatcc ctatagaaat ctataaacta atttctatag ggattttggt
    10861 taactaacta ttctctttat ttttttataa cttttatacc tgtcatatgg tcatttaagt
    10921 tttgttcctc taaagattta tcatctactc tgtttatttc taaagctaaa gtttcagact
    10981 tgatatattc attaaaatgg tcaacagcct tagcaatttc atcatcacca cagtattcta
    11041 ttactatatt atctaatact tcaaagttat tagattttct taattgctgt actttagata
    11101 taaattctct agcataacct tcattaatca actcttcagt tagcttagta tctagtataa
    11161 caaaaagatt gttttcaaca gatacattaa atccttcctt agcagttata cctattaata
    11221 ctaaatcctt attaaattca aaagcttcac catctaaatc aactgttaaa gtctcacctt
    11281 tttcaagttt attagcagtt tcatgagcat ttaatttact taatgctcca acgaataaat
    11341 tcatcttaga acctaataat ggccctgctt ccttaaagtt tggttttaaa ctaaagttca
    11401 tatactcatc taaatcctta gcaaatatta cctctttaac attaagctct tcttttatta
    11461 aatcaactac atcacttatt gtatcttcaa acttaccatc tactaacact ttttgtaatg
    11521 gttgacgaac ttttattctt tctacttctc ttgaagctct acctaaagta actaagtttt
    11581 tagctaaatc cattttttct tctaatttag tatctactaa ctcttcatta catttaggat
    11641 attcagctaa atgaacagat acttctcctg ttaagtttct atacatttct tctgacatat
    11701 atggtgcaaa tggagctata gctctacaaa gaccatgtaa caattcataa gttgtattgt
    11761 acactgcttt tttatcttct gttaattcag ttgcccagaa tcttcttctt gaacgtctta
    11821 tataccagtt agataaatca tcatttataa aatcttgtat cattcttaaa gttttattta
    11881 actcaaatat agctaaattt tcttctacat ctttcattaa attattgaac ttagataata
    11941 tccatctatc aagttctggt ctatctttat attctacaaa aaattcagtt ggatttatat
    12001 catctgtgtt tgcatataaa gtaaagaagt tatatacatt cttcatagta cctataaatt
    12061 tactttggat ttcttttaat ccatccatat caaatttagt tggagtccat ggtggagaaa
    12121 catatagtaa ataccatctt aatgcatctg ctccatattg gtcaaataat tccattggat
    12181 ttactgtatt tcctcttgat ttactcattt tcttaccatc tttatcaagt acaaggtctg
    12241 gaactaaaac actcttatat ggtgcttttc ctaatacaaa tgttgatact gcaagtaatg
    12301 agtagaacca acctctagtc tggtctatac cttctgatat atagtcagct gggaacaatt
    12361 ggtcaaagtt ttccttattt tcaaatggat agtggtgttg agcaaatggc atagccccac
    12421 tatcaaacca acagtctata acctctgtta ctcttgtcat tggttttcca catttttcac
    12481 attttaagtg tatatcatct acatatggtc tatgaagttc aactgtttct ggatttacat
    12541 cttctatagc tttttcagct aattcagctc ttgaaccaac tgaatctgta tgaccacatt
    12601 cacatctcca tataggaagt ggagttcccc aatatctagt tcttgatatt gcccagtcat
    12661 ttagattttc taaccagttt ccaaatctct tctctcctac aaaacttggg aaccatttta
    12721 caccattatt attttctatt aatttatctt taagtttagt catctctata taccagcttg
    12781 gttttgcata gtatactaat ggagtttgac atctccagca gtgtggataa ttatgaacta
    12841 ctttttcttt gctatataat ttattttcag aagctagcca ttttattatt tcaacatcta
    12901 gcccatcttc cattacaaat ctaccttccc aaggagtaga tgtaaattta ccagtttcat
    12961 ctactggttg aataactggt aaatcatatc ttttacctgt gttgtagtca tcttcaccaa
    13021 atgctggtgc tgtatgaact ataccagttc catcttcagt agttacataa tctcctactg
    13081 taataaaaaa tgcttttttg tcaacttcta caaaaggcat taattgttca tattctaaac
    13141 cttctaggtc tttacctttc atttcttcta aaacttcata atcttcacct agtactttat
    13201 cagctaaagg tttagataca taatatacct catcaccttt tttaactttt aaataatcta
    13261 catcagcatt tactgttaat gaaacgtttg atggtaaagt ccatggagtt gttgtccatg
    13321 ctaagaagta ttcatcagca tcttttttct taaatttagc tataactgta ttagttttta
    13381 cttctttata tccttgtgca acctcatgac tagcaagacc agttccacat cttgggcaat
    13441 aaggaagtat tttatgtcct tcatatatat atccttcttt gttgaatttg tttagtatcc
    13501 accatacaga ctctatatag ttattatcta aagttatata tggattatct aaatcaactt
    13561 cataagccat tctctcagtc attattctcc attgtttttc aaatgagaaa actgactctc
    13621 tacatttttg gttaaattca gctattccat attcttctat ttgttgcttg ctagtaagac
    13681 ctaactcttt ctctacttgt atttcaactg gtaatccatg tgtatcccaa ccagcttttc
    13741 tctttacttg ataaccagac attgttttat atctacaaac tgaatcttta agcgttctag
    13801 ataaaacatg gtgtactcca ggatttccat tagctgttgg aggtccttca tagaatacga
    13861 aacttgggtc atctttccct ttttctaaag ttttttcaag tatatttatg tctttccaat
    13921 aatcaaaaac ttgtgcttct gcttgtttta cagaactgtc taccaatggc ttaaatttcg
    13981 ccatgtaaat caccctttcc tactaaatat tataattcca aaatttttta ttctttcaca
    14041 taaatttaaa tactaaaaaa ctcgccccct ttaaaccaaa gggacgagtt ataaatcgcg
    14101 ttaccaccct aattctatat gtaaactaaa tactagctac atataacact ctaatagtat
    14161 aacggtacta accggcacag cttagtagaa tttaatcgtt cagcctgcag ctcaagagtg
    14221 atttttatct ttataaattc attggttctc agcataccca attctctgta aaattatcta
    14281 aagataaatg tctctatcaa cgcttttaaa aatttatctg tgtttatatg aaattctata
    14341 acaaataatt tgaatagtca atatattttt gaaaaatata ataatttcta tttttcttac
    14401 atttttatcc tatttttaat ctttgttata gatttctcaa actcacacaa ttattctaca
    14461 taaaaaataa acaaattaca agcttattct aaagttgtag cagcttcatc attactataa
    14521 ttatacactg ttgttccttc aaatgcgttt acacattttt catctacatc ataaaaaatc
    14581 tcatcaacac ttcttatttc atcttctaac agtgatttaa atttatttct aaatatctta
    14641 aattctttga ctaaagcatc atactctttt cttatctcta taacacggtt attagcttgt
    14701 tctataattt gtctagcttt taaatcagct tcttcaacaa ttatcttagc ctttttatta
    14761 gccgcgctac aagtgtcttc tgctgcactt tgagcagtta ttaaagtagc ttttagtgtt
    14821 tcttcaatat tttcatactt gtttacttgg tcttgatata accctaattt ttctttaaga
    14881 gctgtatttt ccctacatag agattcataa tcttccttga tgatatctaa aaattcatca
    14941 acctcttcat ctctataccc tcttaaacct tttttaaact ctttattttc tatctcaatt
    15001 ggagttagca ttacatttcc tcccagctat aatttaaatt agtccttata caattaatct
    15061 tgcttgaact tttatttttc cttttttagt aatatctcct atttgtgtta ccttagctct
    15121 tcctttgcct ctaatagaaa tcaaatcatc attttttact attttagaag ttgaagttat
    15181 cttttcataa ttgacatgga ctttttctcc atttatgtat tttgcactat cttgtctaga
    15241 tatattgtaa ataccactta tcacacaatc taacctatct gaagatactg taaatgatac
    15301 ttctttatat tttgaagaac tattaacaat attttctctg gaaatttcct ttacaattac
    15361 attatttctt gaaacctttt ctaagtttac aattataaaa tcgcaaatat cactacttac
    15421 aactacttga caaaagctat catgtataat tatatctcca attttttctc tttttatacc
    15481 tagacccagt attgacccta agtaatcttt atgagatata tttttaaatt tgaaattccc
    15541 ttctatttgt aaaaatctaa gagtatcttc tatatcttca tattccatgt aaaatggata
    15601 aataaataca gtgcttcttt cagcttgttc ataacctcca tccacactgt attttatttc
    15661 atttgtagaa tttaatattg ctacagcatt tttcacttca tatggattaa gaaactccgt
    15721 agacttaaca tcatagtttt ttatacaact attagccttg tctatcactt taaacatttt
    15781 atttttcaag tctatatcct ttatgtgatt tgttagtttt aatttatcca tcctatcacc
    15841 ttagaatata accaatacta attgtcttag gaacatcaat aatactattg caattaaagg
    15901 agaaaaatct ataggtccat ttgtatattt atacattata gaccttattg gcccttctat
    15961 tggctctgta agattttcca aaatatcaaa aattttactt tgtcttccat ttggaaacca
    16021 agtcatcaag ctttttataa ctatcatcca tgctattata tctaaaagat aataaagtgc
    16081 aattcttatt gttcccatat attaaccgcc tttttactat ttattttgcc aagggaagaa
    16141 tgctttactt tctaattctt ttttcatatt tgcatctata tccacattat taggagctag
    16201 tataaatatt gatttagaaa ccttttgtat acttccatct aagacataaa ctgccccatt
    16261 cataaagtta aatatagatt tacgaacttc agaattagtc aatccttcca aattcactat
    16321 aactgccctt ctttgtttta gatggtctgc tatagttgca gcttcatcat aaaccttagg
    16381 ttcaactatt acaactttca tttggctagt tgtatgtaaa tttacaattt tatttgcttt
    16441 tgcagtacta aagccactgt tcatttcttc ttcttgaact atatcgtcca tgccactttc
    16501 atattcatct tcaatgtaat cttcttcttc atcaactatc caattcttaa atttagatat
    16561 tattccattt gacattatta acttcctcct taaaatttat tcaaatttga gtaattattt
    16621 tttattgtag tttctttctc caaagattga tgttccaact ctaacaatgg tagccccttc
    16681 ctctatagca atttcataat cgtgactcat tcccattgac aaaacatcca tccctacatt
    16741 agggatgttt agttctttta tttgttttga taaatcttta agacctttaa atacacctct
    16801 tatctcatct tcatcttcta taaaaggtgc cattgtcatt agacccttta tttttatatt
    16861 tttatatttt tctgacactt ctttgacaaa gtctacaact tcttctctat caagtccatg
    16921 cttagactct tctttagata tattcacttg tactaagcaa tctatttctc tgtttatttg
    16981 ttctgcacgt ttttgaattt cttcgcataa tgcaattcta tctaaagagt gtatcataca
    17041 aactttatcg attatgtact taactttatt ggtttgcaaa gttcctatca ggtgccagtt
    17101 taatttatca cctataatat catactttct agctaattct tggggtttat tttcaccaac
    17161 agaagtgatt ccttccctca ttgcctcatt aactaagtct acatcaacag tctttgtgac
    17221 tgccaaaagg gtaatctctt tgctgtctct atctactttt tttgcagctt tatcaatttt
    17281 gtttcttatc tcagacaaat tatctttaat agaacccatt attatcacct actttatcct
    17341 tatatttgtg tttatactgt taggtcttaa aattattttg tcatatagat taacacttgt
    17401 aactccattt atgtcatttt tataataatc cacaaataca gaagattcat tctcataagt
    17461 tattccttct aatatgacaa attttacact ttgtgattgt tcatcaatta catatacacc
    17521 acgtttattg tcttttgttt ttatagaagt tttaggtatt tttaaacatt ccatctgatt
    17581 atatattata tcaaattctt cgacacttgt atcctgattt gcaacaattt ggttacttat
    17641 ttttaatttt accattattt tattattatt ttcatatatt ttgtaaactt ttgcatctaa
    17701 tttttgctca tgatattcaa ttattacatt ttgatttttt ttaaagttat tagaatcttc
    17761 tttactgatg tatgtagata gataattact ctggtcattg gcatcttttt ctatagttcc
    17821 ttttacatga atctttgcat caactttttc attttttaac accaacgtat ctacattttt
    17881 gctaattatc attactaata tattaaatac taaatatata agaataccaa gtatcactaa
    17941 tctggtatat tttacctttt tcaaagactc tccccctata aaattacttt cattataagt
    18001 acttcttcta aaaaatgttt attccttttt tataagctaa tattttacgt tctaataatt
    18061 attttttcca tattaaattt attttttatc aatcttccta tacaagactg cattatttat
    18121 atataattgt attataaagt ataagtttaa tttacatttt atacgttaag cttactttat
    18181 atgtttttat agttattttt atttttagat gcaatataaa accaattaag atttaaaata
    18241 acttttgtta tgttgacatt tatttaggta atcatttatg aattaggata acgttatcat
    18301 aacaaaagtt tatgtcctaa aaaaaataca aggaggattt tcttatgtca gaaattttat
    18361 taggaacagg tttactttta ttggttctat gttgtttcac aatttttagt tacaaggccc
    18421 catatggtat gaaggctatg ggagctctag caaacgctgc atgtgctact ttcttagtag
    18481 aggcattcaa cctttcttta cttggtgatg ttttaggtat ggaatttttt agaagtgttg
    18541 gagctgctaa tggtagtctt ggtggagttg ctgctgctat acttgtgcct ttagccttag
    18601 gtgtatctcc agtttatgca gttttaatag gattatcttg tttagatttt tctatattat
    18661 ctggattcgt tgctggatac tttgtttctt tcttaattaa gtttatagag aaaaaagtgc
    18721 cacctggagt ggatttagtg gttgtaattc ttctatgtgc accactatct cgtcttatag
    18781 catcaaatgt agacccatta gttaatagta cactactaca aattggacaa gttttgatag
    18841 aagctaccaa cattagccct ataataatgg gaattatact aggaggtcta ataacagtag
    18901 ttggaacgtc tccacttagt tcaatggctc ttacatctat aattggtctt actggtcttc
    18961 ctatggcaat aggagcatta ggtgcttttg gttcagcttt tatgaactca acactatttg
    19021 caaaattgaa attaggttct aaaaaagata ttatatctgt tgctattgaa ccattaaccc
    19081 aatcagacat aatttcagct aatccaatac ctatatattc tactaatttc tttggaggag
    19141 ccttttctgg tatcattgta gccttgatgg gtcttgtaaa catgacacca ggtacagcta
    19201 cacctgtggc tggttttgct ataatgtttg cttataatcc agttcaacaa gttcttataa
    19261 cagctggttt atgtgcttta ttcaatgtaa ttgcaggatt tttaggttca aaaatattca
    19321 gtacctttaa agttcttact gctggtgaaa tacgtggtac tgatgtagaa gaagaaattg
    19381 cttaaaaaac aataagattt ataaatttat atctcaagta gtagagtttt atattgtagg
    19441 caattttatt aattgcaaac gttttatttt ttatttatgt ttatgattat tatgtgtgtt
    19501 gaatatttag ataaattttt atttattatt tttatttaga tttttattta ttatttttat
    19561 ttagattttt gtttagtttt ttatttggtt gatatattag gaataaaaat tagtatagtt
    19621 tattactagt tagatagcat aactttttag atacataaaa aattttatat taattagata
    19681 ttattaaaat aaaagcgata catgaatttt taaatgtcca tgtatcgctt tatttttgcc
    19741 ataatcttaa caactaattt ttaaagttta ttatcttaac aaagttcatt atcttatata
    19801 atatttaaat gcatagactt ctttaattta accatctaaa tatttaatta aatattatta
    19861 tatgtaatat aactaatttt taaatgaatg tataggagct ggaatccttc ctcctctttg
    19921 agtaaataat tcagatgaat ttgtatttat aggcattact ggtgctcgtc ctaaaagtcc
    19981 tccaaattct accatatcac ctacatcaca tcctggggct ggtataattc taacggctgt
    20041 agtcttatta ttaatcatac ctattgctgc ctcatcagct atcatggctc caagcgtacc
    20101 tgctgtagta tttcctggca cagctatcat atcaagacct acagaacaaa tagcagtcat
    20161 tgcttcaagc ttatctatac ttaaagcacc tttaataaca gcatcaatca tacctgcatc
    20221 ttcagatact ggtataaacg ctccactaag tcctccaaca tgtgaacatg ccattactcc
    20281 acctttttta acagcatcat ttaaaagtgc taatgctgct gtagtcccat gagtaccaac
    20341 aacttcaaga cccatttcct ctaatatatt tgctactgaa tcaccaatag caggtgtagg
    20401 agctagtgat aagtctatta tcccaaatgg aacatccaat ctactagaag cttcctttgc
    20461 cacaagttgt ccaactcttg taattttaaa tgcagtcttt ttaactgttt ctgaaacaac
    20521 atcaaaaggc tctcccttta ctttctctaa agctctctta acaacaccag ggccacttac
    20581 accaacattt ataattctat cagcctcacc aacaccatgg aaagctcctg ccataaatgg
    20641 attatcttct actgcattac aaaatactac taattttgca caaccaaaac cttttgcatc
    20701 ttttgttaat tctgcagttt cttttatgat ttctcccatt tctttcactg catccatatt
    20761 tataccacat cttgtagaac ctacatttac tgaagcacat actttattag tacttgctag
    20821 agcttttgga attgacttaa ttagtatctt atcacctttt gtatatccct tttgaactaa
    20881 tgctgagaat ccaccaataa aatctatacc taaatcctct gcagccttat ccaatgtctg
    20941 tgcaaacttt acatagtcat tttcatctgt tgcacctgca ataatggaaa ttggagttac
    21001 tgataccctt ttatttacaa ttgggatacc aaattcacgc tctatatctt ttccaacctt
    21061 caccaaatct ttagcagaac tcataatctt attgtatatt ttttctctag ctttatctcc
    21121 atcagggtct atacaatcta ataaagaaat ccccatagtt atagttctta tatccaactg
    21181 ttcttcatct atcatcttta ttgtttcaag tatatttcct acattcacta ttatcacctc
    21241 cccttactgt ctactacaga ttatgcattg aattaaatat ttcttctcgc tgaattttta
    21301 catccactga taatttctta cctctttcaa ccaagtcctc aaccgttttc tcaaaagaat
    21361 ttaatgattt ctctaaatca actatcataa tcatagtaaa ataatcctgt aatatttttt
    21421 gtgatatatc tactatgttg atattttgct tgtataattc atcactaatt cctgccacta
    21481 tacctggttt atcctttcca attactgtta aaattgcttt cataataata tcctccctta
    21541 tttttttata aatcttatat ttttacaaat tgaactatgt gttaacatat atttcattta
    21601 tttgttagta aaccactttt tatgtatata tttaatatat tttaatacct atacattcat
    21661 ttgtcaattt tttttcaata ttctattatt tttatactat ttagaaaatt catatattat
    21721 atatgttttc tcaacaacaa atacagtttt cataataatg aaaggtatta cttagcaatc
    21781 tcatgatttt ctaaataata cctttctaaa aattattttt ttaattttat gaatttaatt
    21841 atactttttc tagtatcagg atttacaatt aatatagaac caatcataat tggtgttagt
    21901 atacaaaata aaaaaataat atcttttttt agattatatt ctttagattc taatttataa
    21961 ttattattta ttattccatc ataatcactt atatttgact tatttttatt tgtatcttga
    22021 tttttgttag aaatactttc cctataagga aaagaatgtt cattggtacc aaatactgat
    22081 tttgagctta aatcataatt atcatcattt tctgtaattg aatttttatt gtaaaatcct
    22141 ttttctttat cagaattatt ttctttatta ccgtctttag gtatatcatg aggattttta
    22201 ttttcattgc tatcagtact tgattctaca tcatctttag gagtatttgg ttgtttctca
    22261 tcagaattat cattttcatt attattattt tcattattat tgttttgatt gttattacta
    22321 tcattatttt catttccatt attcccatct tgattgttat catcctcatc tctatccggg
    22381 tcgtctctac ctcctcctcc acggtcacca tcaatatcat cattttcccg ttcatcatct
    22441 ggcgtctctt ggttgtctcc acctcccatt ataaatcctg gtttaaaaac tatatttgaa
    22501 tacccttctt ttaatcctcc tacaactttt actctaaaac aacgcaactt aaaatcttca
    22561 aaaaaaagta tagcttgatc tctaatatcc tcctgctctt cagatatcca attgattcca
    22621 tcgcttgaat attcaacaaa aaccttactt gcactatacg gcatatcata aaataaaaca
    22681 gctacatatc cattttttgt attttgaaat tccagttcca aattgtctat tggttttttc
    22741 tctataacag atacattcaa aataggaact acatcatcat ttattataat tttttcttta
    22801 tttaacattt ctgttttaaa ctttcctgtt atattaaaat cttctccctt ttccaacttt
    22861 tcataataat cagtaaaatc ccattctaca tctatatcaa gtcgattacc actagatgtt
    22921 tctaatacca tatatttggg aaattttata ttttctattt tatcatcttt acttactttt
    22981 atttcatcac taaatacacc aattccccta tgacaacatt tcacaatatt atagccagaa
    23041 tcttcagcta tagagggtat aagctcatta taatcatcaa ttatataaac tttcttactt
    23101 tctgatataa ttgattgtgc caacttatta ttatctctta gtaacccact ttcattgttg
    23161 ctactatatg cttttattga agtttcttct atctcaacat cacctttaga ataaacacct
    23221 atagcatgtt ctccattcac ttcaatatcc ttatttagta ttctaatatc attttcagta
    23281 taaattccta ttgcatcttt tccatttgcc tttatttttt caacagattc gtaggatgat
    23341 ttaatatgta agtctcctcc ttcttcaacg tataaggctg tcccatcagt agcaattatg
    23401 ttgtttatac caatacttat acttccacca ttttctatat gtattactcc ttcttttcct
    23461 ccttcaccta ttatattcaa ttcattatca tcaataataa atctcccatg attttttatc
    23521 aatattttat atttgttggt atctattgta aaattactgt cataaggaat ataaaatcta
    23581 aactcttcat ctattaccat atcacaagaa agagtataaa ctatttcttc tttattattt
    23641 ttattttctt gaacccacct ttcaaaatct tcaagacaat tttcctcttg tccaaaaact
    23701 ttatgtggaa aacttataaa acacaaaact attatactca taaaaataaa tatctcatac
    23761 tttttcatct tacactccta gaaattttta gctttgaaac aatcctgtcg aaacatatac
    23821 ttcacccact ataatttttc cacaattatc aattattgtc aatttatata agtatcttta
    23881 ttaattgtta taaataaaaa gctacttact aaagcaaaca gacgtttcac tttaataagt
    23941 agctatattt ttataacaaa atagttataa tattagaact tccttcattt acaatttttt
    24001 gtaaagtctt ttgcatttta actcttatct cttctggcat agtatataat ttactttgta
    24061 attgctcttt tactaagtca tgtagtgatt taccaaacat atttgattcc cataaatctg
    24121 ctggttgctc ttcaaatact tccataagat attttatcat ctcttcacct tgattttgat
    24181 ttccaactat tggagaaacc tctgtagata tatctgcttt tataatatga agtgatggtg
    24241 cattggcttt taacttgata ccatattgtt ttccttgttt cattatttct ggttcttcca
    24301 gactaagttc ttctaaggaa ggagctacta ctccatatcc ttttatcttg gcatctatta
    24361 aagcactttc tattttatca tactcatttt taactttaga tagtctagtt atcagactaa
    24421 gcagttgata atctccttca attttaaatc cacttttttc ttcaaggaca ttatagaata
    24481 aatcttgctt tgtctgtaaa tcaatattta taacaccttc tcctagctct acattatcaa
    24541 cacctgtatc ttccaaaaac tctaactcag aaaatccttg tataatacct tctatatccc
    24601 ttattttacc tatatctata atactttgtt ttaatgttgt tattatgcta ctttttatcc
    24661 aatgatttct ttcaagacct tcaacccatt ttggtaagtt gattcttatt tctgtaagtg
    24721 gaaaatcata taatacagct tccataacct cctctatatc ttcttcttcc atttcaacca
    24781 cattcattgg aagaactgga acttcatact tttcttccaa ttcacttcta agcatactcg
    24841 tttcctcact ttttggactt aacgtattta aaaccactgc aaatggtttt ttaagatttt
    24901 tcaattcttg tataactctc tcttctggtt ctacatagct ttttctgtca attccagtaa
    24961 ctgaaccatc tgtcaagaca actatcccta ttgtagaatg gtcttttata acttttttag
    25021 ttcctatctc tgctgccttt tcaaatgtca tagcttcttg tgaccaagga gtggatacta
    25081 atctttgttt tccaccttcc tcatgcccta aagctccttc aactatgtat ccaacacaat
    25141 ctaccattct tacttttaaa gatactgtgt cttttatttt tatttctaca ccatctgctg
    25201 gtacaaattt tggttctact gtcattatcg ttttacctga accactttgg ggtatctcat
    25261 ctcttgttct atccttttta aattcattgt ctatattagg tataaccaac ttttccataa
    25321 attttcttat aaaagttgat tttcctgttc ttacaggtcc aactactcca atatatatat
    25381 ccccctgagt ccttttggat atatcttcgt atatgttatt attcatatta ttcctcctat
    25441 acatctaatc ttattaaatt atatttagag ttaagggtta atattcttaa aatagaaaaa
    25501 taaagactag caatattaat ttcccctata tacaaaaact agtaaactac aatgctaatt
    25561 gaaattatta aaatccatta cattaaaaga cataattata gtcatgataa ttacaaatta
    25621 tatataaaat aatttattat atcgtatata catagactat gctaagtaaa attaaaatag
    25681 ccctctttat attaaagagg gctaaaacaa atctattatt tttttatttt attatacaat
    25741 agtttatata tcatcaccta aaactacttc ttccatttca tgctttttac ttctcatcat
    25801 tagttctatt ccaacttctt taggatttga acctttcttt attacagaat atatagcatt
    25861 agttataggc atatctatat ctaatttttc agcaacatca tgtgctactt cagtagcagt
    25921 tatgccttct acaaccatct ttacttcttt taaagtatct tctaaactca tccctttacc
    25981 tatgagtata ccagctcttc tatttctact atgcatactt gtacaagtaa ctattaaatc
    26041 tccaatacct gaaagacctg caaaggtaga catattagct cccatagcaa ttccaagtct
    26101 gctcatttca ctaatacctc ttgtcataag ggcagctttt gcattatcac cataccctaa
    26161 tccgtcacat atcccagctc caaatgctat aatatttttt aatgctcctc caagttctac
    26221 tccaactatg tctggattcg tataaactct aagtttaggg ctcataaata aatcttgtat
    26281 catctgtgct atttttaaat ctttagaagc aactactacg gtagtaggaa tatcccttgc
    26341 tacttcttca gcatgagatg gcccagatag tattacatat ggattttgtg gtaattcttc
    26401 ttcacagact tgtgataatc taagcccagt ccctttttca agacctttag ctacattaac
    26461 aataacttgt ccttctttta taaatggttt tattttttgg caagtacttc ttacagcctg
    26521 tgatggaact gctaaaacta ttaccttaca atcttttata gttttttcta tatcagtact
    26581 tatagttata ttatttggaa ataatactcc tggtaaatag tctgtatttt ctttagttct
    26641 gtttattttt ttagcttgtt cctcttttcg agtccacatg ctcacatcat tacctttttt
    26701 tgcaagccct aaagctaatg cacttcccca gcttccagta cctaatacac atactttctc
    26761 catgtttaac accacctgag tataatatat ttactattct ttcttttgac caatttttct
    26821 ctctgtccca tttaataatc gctttatatt tgctctgtga ttatatatta ctgatgctgt
    26881 taagaacaga gctactatta aaccagcttt attttttacc ataatcataa atattggtga
    26941 acatcctatt cctacaacag aacccaatga aacatacttt gttatagcta ccaccaatat
    27001 aaatactgct agacacatta gtgttattac tggatttaca gctagcattg cccctagtga
    27061 agttgcaaca cctttgcctc ctctaaatcc taaaaccgct ggccaattat gacctgctac
    27121 aacacatata actgccagat atccagctaa aagagtatct attccaacca atcttgctgc
    27181 aaattctgat attaaaacag ccattacacc tttaagaaca tcacctaaaa atgtcattgc
    27241 tcctgctctt tttccaagtg tcctaagtac atttgtcgaa cctgcattac cagaaccttg
    27301 agtccttata tcaaccccag caattcgctt tgcaactatg tatgaggtag atatatttcc
    27361 taaaagatat gcaactacag caataattat ataactaaat atctccactg aatttccccc
    27421 ctttagttat attttaagat atttattttt tatttttttg tctatactca aactttatgg
    27481 aagttccttc aaatccaaaa ttttctctta tcttattctc aaggtatctt tgatatgaga
    27541 agtgagttaa atccttatca tttataaaca atgtaatttt aggaggtcta atgtcagttt
    27601 gagtcccata gtaaattttt aatcttctac ctttgtcaga tggtggttga tttaacatta
    27661 cagcttctcc aattacttca ttcagtgctg aagttgatat tctcttagaa tgttcatttg
    27721 acacatattc aactgtatct agtatcttgt tcattctttg attagttttt gcagaaacaa
    27781 atacgattgg agcatacatc ataaatggaa atttttcttt tatatctttt gtgtaattac
    27841 tcatagtctt attatctttc tctattaaat cccatttatt gattacaaat atgcatcctt
    27901 ttccttcatc atgtgctata cctgcaacct ttgtatcttg ttctgttaca ccttctaagg
    27961 catctattac tatcaatact acatctgctc tatctacagc actcatagct cttattacac
    28021 tgtatttttc tattgtctca tatattttac tttttcttct aagccctgct gtatctatta
    28081 gaagaaattt ctgtccattt ttttcaaaat aagtatcaat tgcgtctcta gtagttcctg
    28141 caattggact tacaattact ctttcttctc caagtatctt attgagtata gaactttttc
    28201 ctgcatttgg tttacctgtt atagctactc ttattatatc ttcttcatac tctgtatcta
    28261 atcctgctgg aaaattttca actatctcat ctaataaatc tccaaatccc atactattgg
    28321 ctcctgaaac tgcaaaaggc gttccaaatc ccaactcata aaaatcgtat atattatcaa
    28381 attgactttg actatcaatc ttattaacca ctaagattac tggttttttt gtctttctaa
    28441 gcaattgtgc aatttcttta tcagcagctg ttattccagc tttaccatca actataaaaa
    28501 gtattacatg tgacatgtcc attgcaagca tggcttgatt tctcatttga gataatatta
    28561 tatcttcgct atcaggttca attcctcctg tatccactaa tgtaaaatat ttatctaacc
    28621 attctacttc agcaaatatt ctatctcttg taactccagg tgtattttca actattgata
    28681 tcctttttcc tgcaaattta ttaaatattg tagacttacc aacgtttggt ctcccaacta
    28741 cagctacaac tggcctactt atactcattt tatttctcct tccatctttt gttttctatt
    28801 ttaaaatttt atccacaaaa tcttttcctt cattcaaaca agggataatt tttattctca
    28861 taagttcttc taattgattt aattcaatat tatctaagaa aatttcttca tctgctttta
    28921 gcatacttct tgttatataa agagcgtctc ctaattcttt atcttcaagt tgttctttta
    28981 aatccttagc tgttaaaaga cctgatacag ttattgtctc tccaaaaaac ttgtttttga
    29041 tttcatatac atttacttga agatttttaa acttgtccat catagcatct gccatactct
    29101 gtataaattc atatgcagaa tgaccagtag ctattgatac tttcttctct ctttttagaa
    29161 tcttctcagg caatatattt agatactctt caatctctgt ttttaactta cgtatcatac
    29221 ctacaccatc ttcaaactgt aaaaaacctt catattcttc atatccaggc aattcactat
    29281 tagatagtat ataaaattca tctgataaaa atgcaaatcg agtacctaat ttttcaagat
    29341 atttctgttg tatttgatgt atttgctcta tagttttact tgcgctctta tcattaaata
    29401 tatttaattc tactagattt tctctatgct ttgtaatccc aactggaact atcgcaacac
    29461 tgtttacata cggataaagt tgagctagtt cttttattgt tctatccaat tcctttccat
    29521 catttatacc tggacataaa acaatttgac agttcatttc tatatgagca tctgccaatc
    29581 tcttcattat accatataat ttccctgcaa atttattgct tatcattttt tgtcttaact
    29641 ctggattagt tgtatgcaca gatatattta taggacttat tctatatttt ataatattat
    29701 ttatatcttc ttcactcata tttgtaagtg tgacaaaatt tccttgtaaa aaagataatc
    29761 tcgaatcatc atctttaaaa taaagagttt ctctcatacc ttctggcaat tggtctataa
    29821 aacaaaacat acacttattt ctacagcttt tagcttggtc aattatcgga tttgtaaatt
    29881 caacacccaa atcttcatca tagtcttttt ctatctcgta tatgtagact tcgccatctt
    29941 ttttttgtat ttctacatct aaatattcat cacttagtaa gaatctatac tctattatat
    30001 catgtattgg ctgttcattc acagatataa gtaaatctcc tacctctata cccacttctt
    30061 ctgcaatact atctttataa accttactta taatattatt tacttttttt acatttactt
    30121 ccaatatttt caccactctt ttgtattcat caatgcttat tataatgtat tttaatatgc
    30181 aatttattta tttattatat tttatgatag catttttaag catttcatgt cataataaca
    30241 cattttaatt ctaatagtca atataagtaa atagctataa aatagattag aacaaataat
    30301 attcaaattt aagtttctta aaaatttaaa tattatttgt tcttaaaaaa attttataaa
    30361 tttaatgttt tactatgatt aacgtcccat ttgtcatatc atgaaccatt ccacctacac
    30421 actttgacat caacaatgcc ttattttgta agtctttctc atcatttgca taaaatattg
    30481 gacaacctcc accatttttc atattcttat caagtgtaac tatagctagg gtatattcat
    30541 ttaaacctat atccattccc atcttatgca cttcctttct ttcctatttt ataatttttt
    30601 agtgataagt tttttccttt agagcttgaa agtattgggc atgactttac agcttccatt
    30661 actttttcca cattcttatc tactggtaaa taagcaatca ttatactttc atcctcttta
    30721 tttcttctag gtaatggtac gaatgaaggt tctccataat ctccatataa acctaacctt
    30781 gaatatatat tgtatactat tgcttgtctt tgaccggagt caaataatat tcctgcatta
    30841 gcataatcct tatttttagg aattatttgt attcctacac ctctattaat atatacttct
    30901 ctatcgcttt ttagacctat atttgttata ccttttaaat ctcccacctt tagtatagat
    30961 tcgtccacaa aactaatttc agcaggcatt acatcagcta tgtctccaat actttttcta
    31021 gtaagaagtt tttttaatat aaaggctaac actaatccac aaattgaact tattaccaaa
    31081 ctcatccctt cacttatttt cgtttctgca agtattacat aatacaatcc tattgttaaa
    31141 aaagatgtaa ctatacacat ataatttctt acttcatagg ttctagctat ctcttctatg
    31201 aatgcagctc ctctctttac aagttgaact tcctctaaat tttgcaatgt atttcttcta
    31261 tttgctctca cttgtctaaa ttgttctgct gctagagata aaaatgttat ggatgtataa
    31321 gaacgattta taagagctgg aaccaataat gctcctaatg aagaagcgac gaatgctaat
    31381 ataagttgag atagtaaaac atttggttgc gttggatact gtttttggtc taaattcaac
    31441 attataattc tagatgttat accaataata acagcaacaa aaaatactct atccattaaa
    31501 tcactcctaa aatatttaat ttgaaatttt acatgtaaat ctacaaagtc tttctagaaa
    31561 aatcactctg ctttcctttt gatgtttcta tgataggtgt acttttcact acatctatca
    31621 tgacatctat atctttgagt attggcatat atggtataac cacagtactt ttttctaaat
    31681 tggtcttaga tatagcaaca atatcaacct catctacatc tctatctatc cccatatgaa
    31741 taaatagatt atgtattata gcttgtcttt gccctatatc atttactatt ccaaatgcac
    31801 ctaaatctct tggtataact tctatagcca gacattcatt tctatacttt tctcttgtac
    31861 tttctagacc tatgttagtt attattacac catttaccat taaaataggc ccttcaaaac
    31921 ttatttttgc aggaactata tctgctatat ctgctatact gttccttctt aaaaatcttc
    31981 taaaaatcaa accaacaata gctcctgaca caatagctaa gattgtgcaa taaaaaaagc
    32041 taaggccata ctttcttgca aaaacgatat aaactatcga agataccagt gcagaaaaaa
    32101 gacttatata acttctagat tcatacgtag atgctatttc ttcaacgtaa gcatctcctt
    32161 ttggtactaa ttcttcatta tcgatattct ttagtgttat tctttcttgt tctgcaagac
    32221 cttgaaactg ttgtattgct actgcaaaaa atgtcaaggc tgcaaactcc ttatctataa
    32281 gtgcaggtaa tgctatagca cctaacgaag ctgaaagccc agatataatt atctgttcta
    32341 aataatcttg tggtcttgat gggtattgtt tgtctgtaac tcttaaaact aatcctctac
    32401 ataatattcc tacaactaat gcaactataa aagagtgtct aaataaattt gcattcaata
    32461 aactttcttc cattttctca gctccttctc ttatatagtt tgtgcaaaaa acaaaaaaaa
    32521 ttcccttcta tttaaggaaa tttttttgta atattgtaac tataaattcg ctaccaatgc
    32581 caagttcact ttttactttt atacatccat ttagtgattt gactatatgc tttgttatag
    32641 ccaatcctaa acccgttcct cctacatccc tacttcttgc tttatctacc ctataaaatc
    32701 gttcaaatat gcgttctaca tcttcttttg gtatccctac accattgtct ataactttaa
    32761 ttacgatttt ttcttcatct tttaacacta caacttgtac aatcccatta tcttgggtat
    32821 actttatagc attatcaact aggtttaaga acacttgctt tatatagtct ttattggata
    32881 gtatacttat tgatttatca tcacatttat ataaaacttc tatatttttt tcactagctg
    32941 aatgttgagt tatttcatat acctctttaa atacatcata tactacaaca ttttccataa
    33001 gaagagtatc tttattttct acaaatgata acagcaatat atcatcaatc aaccttttta
    33061 atctatctga ttcgctttct attatttcta agaatctatt tctagtattc acatctatat
    33121 tttcatttga ctttagtgtt tcaacaaacc cacttataga tgtaagtggt gttttaagtt
    33181 catgacttac atttgcaaca aaatcacttc tcatattttc aagtttaact tttttagtaa
    33241 tatcttctat atttactatc gaacctatta ttacgttgtt agtattctga agataaactg
    33301 ggtctacttt tatcttatat acgatatcat ctttagtagt aatattagca gtttcattat
    33361 ctttagaacc aataaattga agtatttgtt ttaatatttc ttcttctttt attacaacat
    33421 taatattatg accttcaact aattgatttg gttcactctt tatcatttct tttgcttcat
    33481 catttatcag aagtatattt ccatttacat ctatagctaa aattccatga gatatactct
    33541 ttaatataga ccttaactgt aaatgtttat actgtacttc ttctaaggtt ttatccatat
    33601 tctttatcat atgattaaaa tttctagcta attcgccaag ttctcctttg gctgatatgt
    33661 taagcctagc atgatattca ttattactta ctttttttga gacgtatata aactctttta
    33721 aatattttct taatgttatt gtgtatctta cagctaatat aacaatggct atggacaaca
    33781 taacaataaa aaaatatata ctatttaaat cttccacaag ataacactcc taaaatataa
    33841 cctttttaat ctattttgta tcctacacct cttatagtct ctatatattt ttccgattta
    33901 tcttcatctt ctattttttt tcttaaatat cttatatgaa catctactgt tctagtttct
    33961 ccatagtatt cataccccca tattttatcc aaaagataat ttcttgaaag tacttttcct
    34021 ttattttgaa ttaataattt taacaattca aattccttaa gagttaactc tatcttttca
    34081 gagcctttgg taacttcatg ttttgataaa tctagtttta aattacctgt agtaagtata
    34141 ttgttttctt cacctaagct agtcaaatta tatctcctta aaacagaact aatcctagct
    34201 aacaactctt ttatactaaa tggcttagtt atatagtcat cagcacctat ttcaagccct
    34261 tcaaccttgt cattttccat atttttagca gtaagcatta taacaggaat attttttaag
    34321 tccttatcac ttcttatttt tctcaaaact tctattccac ttatatttgg taacatccaa
    34381 tctaaaagta ttaaatctgg tttaatttcc ttagccttta taaatccgtc aaatccatca
    34441 tatgaataac taacttcgta atttgacacc tccaaattga attttaatag ctcaactata
    34501 tgcatttcat cgtctataac aagcacttta gtattcatta aaaagctcct ctctatttta
    34561 tctgtagtac cgttcctatt cgttctgatg ccttattatg ttttctataa gagtggaatt
    34621 tatctgctct acaactagtg cataaattta aatttattat attttctttt ttaactccac
    34681 tacatctaag catatactca ttaattttcc ataaatctaa atagtaactt ccctctttta
    34741 ttatatagaa cttttcatca ttatttgtaa gaattgtgtt aaatttttct actaaatctt
    34801 cagacacttc ataacaacat ggtccaattg atggtccaat tatacatact aaatcttcag
    34861 gaactgtttt atagcattca gacattaatt ttattgtttt atgacctata ttactaaaag
    34921 tccctctcca acctgcatga gccagtccta tggctttatt tttagcatct ataattgata
    34981 taggtacaca gtctgctgta aacagtaaaa gtggtacttt ttccaagttt gttataagtg
    35041 catctccatc tcttcttttc cctatagtat ctttattgac tatattaact atatctgaat
    35101 gtatttgaga attactagtt agattttcaa atgtcaaatc acattcttta catactttta
    35161 acatatcttc tctatttttt gcatctatat tcttacatgt tataactaga tttacagaat
    35221 ttagtttttc atcaagttct tcacaattac cacttaaatt aacatactct ttaatatctt
    35281 gtacattttt tatatttata taatctttca tcatttgtct cctttttcta tcagtatact
    35341 tttaagttca tttacaaaag tatttatatc tttaaattgt ctatacacag aagcaaatct
    35401 tacataggca acctcatcta actctttcaa tttatccatt accatctcac cgattttttt
    35461 ggtttcaatt tcttctataa aacatttatt tatttcattt tcaatatgta caacaatact
    35521 ttcaatctcg tcaatagaaa caggtctttt ttcacatgct tttaacaatc catattttat
    35581 cttttctcta tcaaaatatt ctctactatt atccttttta atgaccatta aaggagttgt
    35641 ttctattttc tcatacgtag taaatctctt tttacatgat tcacactcac gtcttcttct
    35701 gatagatttt aaatctgtat gtctagaatc tattaccttt gattctttat aattacaata
    35761 aggacattgc atctatattc ctcctttgtt taactatatc tcaaactcat ctaagcttaa
    35821 ttctgaacct atatttacta ttattgtatc acaacctatt ttaagtatat cattccaaaa
    35881 tataacttct tcatcccctc ctcttgaaaa aaaacttcta cttccatctc caaaaatggt
    35941 aaatgagact accttacctt cgtgaatatc catgtctatg tctattataa accccatcct
    36001 ttttccattt tttacattta taatttcttt ttccattata tcagaaactc taatcatatt
    36061 gtactcaccc tttctttaaa aataaatatg tatcgaagta aaaaaaaatg acctatatag
    36121 gtcatttaaa ttaaaataat gtttacagtc catggattac ttatacatat tttctcatat
    36181 tctttaaagc atttttttca attcttgata cttgtgcttg agatataccg atttcatcag
    36241 caacttctat ctgagttctt cctttgtaaa accttaaatc taataccaac ttttctctac
    36301 tatttaattt cttaatagct tctttaagtg atatttcttg caaccaattt tcatcagtat
    36361 cttttttatc ttgaacctga tccataacga atattgcatc tccattgtct tgatatactg
    36421 ggtcaaacag agatattggg tcttgtatgg catcaagtgc cattacaact gattctactt
    36481 ctaattctaa ttcctttgct atttctgata ctgtaggttc tttagaattt gttctaatta
    36541 atctttctct aacttgtagt gccttatatg ctatatcttt taatgaccta cttactctaa
    36601 ttgggttatt gtctcttagg tatcttctaa tttctcctat aatcatagga acagcataag
    36661 ttgaaaacct tacattttgg cttaaatcaa agttatctat agcttttata agaccaatac
    36721 aacctatttg aaataaatcg tctatatttt ctcctctgtt gttaaacttt tttattacac
    36781 tcaagactaa tcttaaattc cctcttacaa actgttgtct ggcttcttca tcaccatttt
    36841 ttatttgtaa taaaagttcc ttcatttgct tatttttaag aactggaagt tctgatgtat
    36901 taacaccaca tatttcaacc ttattaactt gcatatattt tcagtcctct ctcaaaagta
    36961 ttcatctatt gaaattattt acatttccaa tttttttata ctttttaaga agaattaatt
    37021 tagcattata caaatttttt catttctttt tgcaaccttg agattatttt cttttcaagt
    37081 ctagatatgt aggactgtga tattccaagc attccagcaa cttctttttg tgttttttca
    37141 atacctttat caataagacc aaatcttaat tccataattt gcttttctct gtcacttaat
    37201 ctgtcaagtg ccataaccaa caaatctcta tctatttctt cttcaattat tttgtatatt
    37261 tcatcatttt ctgtacccaa tacatcagat aataaaagtt cgtttccatc taaatctata
    37321 tttaaaggtt catcaaatga tacttctgtt ttctttttat tattttttct taagtacatt
    37381 aatatttcat tttctataca tctcgaagca taagttgcca attttatatt tttattcagt
    37441 ttaaaagtat taactgcttt tatcaaacct atagttccta ttgaaatcaa atcttctaca
    37501 tctatacctg tattttcaaa ttttctcgat atgtagacta ctaatctaag atttctttct
    37561 attaaaattg actttacact ttcatctgtt tctagctttt gtaaaagctc catttcttct
    37621 tctggtttca atggaggagg aagtatattt gcccctccca tatagtatat tccctttggc
    37681 tttattattt ttaatttaat acctaacata gtaataaagc ttattattct ttctttcaat
    37741 cgtaacattc cttgtccccc ttaaattttc acctaaaatc caggcaatat atttggattc
    37801 attattgctc catattctct atcattaaaa tttgaaatac caagtattat atttcctatc
    37861 ttttgctcat ctacttctat atagtcagct tttaagccta ttattatgct tgtcttatta
    37921 cttccagcat gtttataagg tattattcta actctacctg aagttttatc atctaaactt
    37981 cctataattt cttgtgcttt cttcatatct atatcttcat aattaatatt taatagtttt
    38041 tctggaataa atccttctaa cacactagac ttaactatta ttacatcact ttgacttatt
    38101 gggtctttta acaaattacc actatctact aaagctttac agcaaaaact tttttctagt
    38161 aagtttatat ttatagtctt tgtaagctcc ttaatgtact taagcatttt caaatcttta
    38221 taaatgtatt ttaataattc acaactcaca taagtacatg caattaagaa agatattttt
    38281 aagtgactta ttcctgtaaa ataaattata aaataagtgc ttccagaaat aaaaatgttt
    38341 actagataaa aaactaacgc tacatgaaca taatcttttt tgctcttact tctaaatgaa
    38401 attaaagtta ttatactcat gattattatt ttaaatggta cagtaaatag tatattcatt
    38461 gatggataca aataagcaac agaataggca cctcctaaac tagcccccaa taacttattt
    38521 tttttaggat tatatctttt agtaagaata gaagtacaac ttataataat ataatttatt
    38581 actaggtttt ctataacata gtactcaata tacaccatgt atcccccctt aaaaccttta
    38641 aacatattat aagatagtat gtacaaaatt ttatgtcact tttgatggtc gaatccaaaa
    38701 caaattctat ttaaaaagaa caatgatata tgtcttatac tttatgtcgt caaaagatat
    38761 ttttttaatg ccaaacaaat agactttttt gtagaatcca atatatctag gtagaagtta
    38821 ttcgctctac ttttggtata tttacaaaaa aagactacat aatttaataa tatatcaagt
    38881 aaatctttta cttatataaa atcaaattat atagtctgta aattcaaata taaattattg
    38941 tgctagtaat ccatttgcat attttgcaga ttcatttagt gcttgttctg gagttatgtc
    39001 tccagctatc atcatttgaa gttgtttcca taaatattca tatatctcta ctccatgagg
    39061 tccaactgtc aatggtctat acatatgttt atctcttgtc accatttctt caaatcttgg
    39121 gtctccttgg tatttttcac ctttagcaac tggagctcta ggtatttctt tgtggaaagc
    39181 ttccattgat tctttgctta gcatatactc aagaagttta aatccaagtt ctttattttt
    39241 acatgctgac attaatgtta aatcatctac tgaagcaaaa cttccaactg tcttatcttc
    39301 taatgatgtt acatatcccc agtttaaatc cgggaatgat ttatcaaaag tacttgtagc
    39361 agcagaggat agcattatag taaatgcagc ttttcctggt ccaaatacac tttcaatcat
    39421 ttcattacta tcttttgata aagcatcttc tggaatatac tttttcatat catttataaa
    39481 gtttgcagct ttcaagcctt ctgcattatt aaatttaact gattttaaat catcattata
    39541 tatatctcca ccagcttgcc ataaatatgg ataccagttc cagtttaagc ttccaaatac
    39601 tttagaaccc caaccttgtg caagacccca ctggtcgatt tttccatctc catcagtatc
    39661 ttttgttgct ttttcacaga ttcttttaaa atcatcccat gtttttggag gtttttctcc
    39721 taatttttct agtatatctt tattgtagta caatacgcct ggattagcag cttctatagg
    39781 taaaccataa ataccaccca tcatttttgc atcatctaag tatagataat tatctgaagt
    39841 tcctgatttt tctaaataag gtgttaaatc ttctaccgca cccatttcta taaattgagg
    39901 aaacatctct gcatacatgt atcctatatc tggaccttca cctgcactta ttgctgttgc
    39961 atatttttct gcgtagttat cccatggtac tatctgaaat tcaatttcac agttattttc
    40021 tttttcaaat ttttcaaata tcggcttcca tgcatctgca tcatggtctg ttaatggtgc
    40081 agaccataca actaattttt ctttaccctc tttgccttta gaatcttctt tttttgaaca
    40141 tcctgcaaga attgatactg atagaatccc taccataact aaagaaagaa ccttttttag
    40201 tttaatcatg cttaatcccc tttcagactt taatttgtct ttttcctcaa atgtttacat
    40261 ttaattcaga tttaatatta acaaataaga ttactcttgt ctaatcataa aaaactatac
    40321 taactcctat aactatattt tttttctata cctattagat ttaattcata ctaaaaactt
    40381 actttttaaa ttttatcaat atttaaaaat ttttttaagt ctagccacaa actaactatc
    40441 taaattgagc aaaataaaaa gaagtctatt gacttcttta taagcttaca tattatcttc
    40501 ttcttcttag gaatgtaggt atctccatgc tctcatcatc atcttcttca attatacttg
    40561 cctttttagg aggctctatt ttttcctcag caattacttc ttcttcaatt tcttttacag
    40621 cttgttttac tgttgtattt aatgaagaac gtatgcttga tttaggttta gtatctaaat
    40681 ctaaggcacc attttgtaat ccttcaaatc ctgtcgcgat tactgtaatc attatttcat
    40741 cacctaaatc ttcttttata gaagctccaa atataacatt tgcttctggg tcacaggatt
    40801 ccataactaa agttgatgcc tcattaactt caaataatcc taagttagga ccacctgtaa
    40861 cattaagaag tactccttta gctccttgta ttgatgtttc tagaagtgga gattgaatag
    40921 cttgtcttgc agcatcaatt gctctagttt caccactagc actacctata cccatatgag
    40981 caagtccctt gtctttcatt atagtagtaa catctgcaaa gtccaagttt attaaccctt
    41041 caactgctat aaggtctgaa attgattgta taccttgttt taatacatca tctgcaactg
    41101 caaaagcatc taacattgat gtattttttt gtactatctg taaaagtcta tcatttggta
    41161 tcgttataag agtatctact tttgatttaa gttctgctat tccaccttca gcgttcttca
    41221 ttcttatctt accttcaaat gcaaaaggtt tggtaactac acctactgta agtatcccca
    41281 tttcttttgc caagcctgca accactggag cagctcctgt accagtacca ccgcccattc
    41341 cggctgttac aaagaccata tcagctcctt gaagtaactt tactatttca tctttactct
    41401 cctcagcagc tcttttccct acttctggat ttgctcctgc tccaagtcct ctagttaatt
    41461 tttctcctat ttgaacttta tattcagctt ttgatgtata taaagcttgt ttatctgtat
    41521 ttactgatat aaattcaacg ccttttagtt gagcttctac cattctattg acagcattgt
    41581 ttccaccgcc acctacacct attactttaa tttgtgcaca ttcttctaat tctacgtcaa
    41641 agtttagcat cataaacccc cttctctcat gattcaaagt tatcgtatgt attaattata
    41701 tcattttctt cttttatttt gttaaccttt aagtaacata ttccacaaaa acgtaaattt
    41761 tcctttttaa atttcttact tatattgtca aatattactc tttaagtata aaataattta
    41821 cgtatatatt aaatgctctt taatttttac gttttttgtt cataatatta ctaataatat
    41881 atcgtctaat tatagataag ttattaaaca atctcatacc aaaaactaat acagcaacat
    41941 agtaaagaga aactcctaac ttttctccta tataagtcaa taatatagcc aatatagcat
    42001 tacctatgaa accagtaata aaaattacat tatcatagtt atcttcaaaa ttggatttta
    42061 tcgctccaaa aatagaatcc attattgcaa gaatagctac tgacatatat atggaataat
    42121 ccatagaata tgtaaatgga atatagtaac ctactactac accaaatgct aatcctccta
    42181 aaacccataa cataaatctt cacctcttta ttttactttg aaacacaact acattacaat
    42241 cctttttatt aatttttttt actttttctt tatttttttg tatttttcgt tttattttgc
    42301 aaataaattc actttatttc cattattttc ctgaactttt atattaattc catatatatc
    42361 cttaagagat ttagcatatg attctggaga gtttatagct gcactcaata aatctatatc
    42421 tcctatagct tttattataa atggttgtcc atatgtagta tcatttactg taatagtagc
    42481 tcctgaacat tttatcttac ttgttgctag tactctttct ccatttatag aaattgctct
    42541 tgctccagcc ttttttaaat catttaaaac cctcaaaata tctatatcat gtataatcaa
    42601 atcgtttgga ttctgtccgt cttttaactc tctctcacta tccctcatag taatagttat
    42661 gcctggccct gtaacagttg aataaccact taactcttta acttcttcaa gctctttttg
    42721 cataagtgtt tggatagatt catttccatt cttttttgct tctttatatt cattcaaagt
    42781 ttttttgttc tttttaagag tttcttttaa attttttatt tctttttttg tattttctac
    42841 ctcactttca atactttcag tttgacctaa tgttatgtat actctatttg ggtctagtga
    42901 ttttatataa gttgatatga aaacgcctaa tatgaatgct cctaatataa ctattttctt
    42961 tttcatacta ttatttcccc tctgctttgt ttatatcact atgaccattt atttctatat
    43021 tgtcttcttt ggtcactttt actttggcat tataatatgt ttctatttcc cagacaatac
    43081 catactttat attaagtgct gaagccaatg tatcagaatc accaattgct tttattataa
    43141 ttggttcttt tatgacagtg tcattcatat aaagcttgtc ttcttttaaa tacatatatg
    43201 tattagaaac tattctctgg tcgtttatag atatggcact tgcttgtgct gaatttaatt
    43261 tatttatcat tgacaataat aaatcataat tatatagtat actatcattt ttatcagagt
    43321 ttcctaagtc ttttgtagaa tttatctcaa tttttatgcc tgttccttca acatctgtat
    43381 atccagctaa tgtttcatat ttttctattt ctgacttaag tatgtcttgt tctccttcat
    43441 tgtttttgcc tctataagtc tctatagctt tcttcacact attaacttct gattgtagat
    43501 tctctttttc tttttttaat gatttaagtt cttctgtaag ttgctctcct cttttaaaag
    43561 ttgtcatccc tctattttct atattaataa ttttaagttg taaactaaca agaacaccca
    43621 atacaatact tcctatgatt atacttttat ttataaatct ttttttcaat atatcacttc
    43681 cttacaattg tctatccttc tggactatac actgccaact ttccatagtt aagatttata
    43741 gtccctccat tagtattttt attttgcagg tcaatcagaa ttttacttac cctagatata
    43801 ttataatcta agttatcatc attagaaagt aagattttta tattacttct tgtaagcatt
    43861 tctatattgc tttctttttt taagtttaca taatttattt ttctataaat tccttcttct
    43921 tttaaataat ttaaagtttt aaatacattc tccttagttt tataattttt aaattttata
    43981 gatttattat catcaatgct ataatctaca tctactatca agtctttttt actttcatta
    44041 gaacctctta gttcttccaa taaatttcct tttttatcta tataacaata attatcttca
    44101 tcttttaata ctgcaaatat ttctttttct tttaaactta taattatctt attgggaagt
    44161 tttcttttta tttccacatt ttctatatat ggatttttta taagtttatt tttcatatct
    44221 ttaaaattgt atgcaaaaat attttcattt agatttacat ttagttcttt cattatattt
    44281 gatttggtca ccctcttatt tccaattaca tctattttct ttacatcaaa taaatcactt
    44341 tttacaatta tacatataca aaaagataac ataagtataa aaactaaaac tatcatgaca
    44401 ttattcgtat ttaactttct tctttttttc aaatataatc aacccctttg gttaataaat
    44461 acacctttag agcttgtttt tcctacaaaa aaattataat atttaaagtc aaatttttgc
    44521 attttattac ataacatcca aataaggtat taaattttat aaataaatca atatttcatc
    44581 aaaataaaca tagcatacta catactattt atatatttaa atctgtatac atacaaataa
    44641 acccctaatt tataataatt tagaaaatct aatatattat aaattagggg taaatattta
    44701 cttatctttt ctttattcct attaccttag cttgaccttc tatacttgga gtcgtttctt
    44761 tttttatttc ttttacttcc ttaataactt tttctttttt tgttttttta gaagttgact
    44821 tttgtgttga attgtatact ttcattatct catcatatat aaggtctatg gcttcaggct
    44881 tacctatagt tttacttgca tttgccatat caaccaaaag ttctctatct cctaaaagtt
    44941 taaatactgc tgtatttagg ctctctggag ttagattttt ttctaaaata gcaattcctg
    45001 ccccttgttt ttctatactc ttggcattat actcttgatg attttcagca gtataagctt
    45061 taggtattat tatagatggc tttccaagag ccgttatctc agctaatgaa attgctcctg
    45121 cgctacctat aaccaaatca cttgctgcaa gtgcatttgc catatcttct aagtaaggca
    45181 caactttttg gtatggttta agatttatat cgctaatact tcccataaat tcatcataat
    45241 agcttttgcc tgtagcaaat ataaaagcta tatcttcatt taccatattc tttattacaa
    45301 gtctcattgc atcatttatt tttcttgaac ctccactacc accatagcaa agtaccattc
    45361 ttttttcgtc acttattgat agattctttc ttgcaatatt ttttcttgat aataaaattt
    45421 cttttctaac tggatttcct gtaaaaacta atttatcttc tgctgcctct ggaaatcttt
    45481 tatgcgaatc ttcaaaactt gtaagtacct ttgtaactgt tttagataaa atcttattag
    45541 ttacaccagg aaaagaattt tgctcatgta ttatggctgg tattttcccc atagatgcat
    45601 taaataaaac aggtccacta acatatccac cagttcctat aactatatct ggtttaaatt
    45661 tcttaacaat ctttcttgat tgctccaaac ctttaaaaag cttaaaaact ctttttacat
    45721 tatcgaaatc tatttttcgc ttaaaacctt gaactgttac agtctttaat tcaaatccat
    45781 acttaggaac tatttctgac tctattccct tttccgtccc aacaaaaatt atctcagcgt
    45841 ctggatgctc atctcttatt ttgtttgcaa tagctatagc tggatacacg tgccctccag
    45901 ttccaccgcc tgataataaa actttcatca aatcatcatc tcctgttaat taattttgac
    45961 atgctttgag atgtttaaca ctattcctac agctcccata aagatggtga gtgaagttcc
    46021 tccataactt ataaatggta gtgctacacc tgtagctggc attgatgatg tcgcaactgc
    46081 tatatttaaa gctgcttgta ttccaatttg tgcacctata cctataacaa ccatacaagc
    46141 aaatacatta gaagtcttca aagctattct tacacatctg tagactaaaa ctacaaatag
    46201 cataataact attatacaac caatcaatcc taactcttct cctattatag caaatataaa
    46261 gtcattttgt ggctctggta tataaaaata cttttgttta ctctttccta agcctagacc
    46321 aaacaatcca cctgaaccta gtgcatatag accttgtatt acctgatacc ccttaccaag
    46381 agggtcttga aaagggtcta aaaatgatgt aacacgacta agtctatagg gttcagcaat
    46441 tactaatgca gcaaataaag cagccccact ccctatcata gcaaatacaa ttttcatatc
    46501 cattccagca acaaatatca ttacaaaagt aactagaatt acagtacctg ctgttgacaa
    46561 atttggctga agtattatca acgcaaaaaa tatccctgga actacgagaa gtggtacaac
    46621 accttttgtc aaagatttta ttttatcata atttttttca attaattttg cagttaatat
    46681 tattgtagca aactttgcga tttctgcagg ttgaaatgtt aaagctccta ttcccaacca
    46741 tctttttgct ccgtttgctt ctatccctaa aggggtcaaa actaacaata ataatactac
    46801 tgctatagct ccaattgctg tagcattttt cttccaaaaa ctataatcta ttcttgatgt
    46861 aataatcata actataaatc caagtacagc atatattaca ttctttttta gaaaatagta
    46921 cgcatcattg tgtttaaatg aagattgtat aaaacttgca ctaaacacca taactattcc
    46981 tacaaatact aaaagcatag tagtgtaaaa cactactcca tcaaattcag tcttcatcct
    47041 tatgtcaatt tgttttttca aattttcttt aggcatccaa ctaatctacc tccattcttc
    47101 catttaagta agtttagagg taagagatta ttttaaattg tttacattat ctttgaagtc
    47161 ttttcctctt acttcaaaac tttcatacat atcccaactt gcacaagctg gtgaaagaag
    47221 cactatatct ccactttttg aaatttcata agaagtctta actgcttctt ccatatcttt
    47281 tactatatgt atgtcattaa atcctttatt tttagcacaa ttttctatat ttgatgcagt
    47341 ttctcctaat aagaccaatg atttaacata tgactttgca gtttcaagaa gttcatcaaa
    47401 attacttccc ttatccatcc cccctgctat aagtattata ggtctatcat aagactgtat
    47461 agcttttata gtggaatctg gattagttcc ctttgaatca tttacatata ttacattgtc
    47521 taaatttctt acaaactctt gtctgtgttc cactccttta aatgtcataa gtacgtcctt
    47581 tataacttct aaatcaattt tgcagacata tgctattgct atagctgcca tacaattttc
    47641 taagttatga cctccaggta aacttacatc atctttattt agaaatttga ttttatcatc
    47701 tatatctatt attatgtcat tattttctaa atatactcct ccatttactt ttttagttct
    47761 tgaaaagtaa attactttgg cattgcattt atcagctaaa gattttacta tctcatcatc
    47821 atagtttaat acacagaaat cctcaacagt ttggttcata aatatatttg cctttgcttc
    47881 tatgtatttt tccatagtat ggtgtctatt taaatggtcc tctgtaatat ttaatattgc
    47941 gcttacttta ggtctaaatt catctatact ctcaagctga aaactgctta gttcagttac
    48001 taacacagac tcttcacttg aagtttctat agtatctatt acaggatttc ctatattacc
    48061 aactacatat gtatctcgtt ttgctcttga aaaaatttct cctaccaaac tagttgtagt
    48121 tgtctttcca tttgtacctg taatccctat aaaaattgga ttattcgata gtttaaaagc
    48181 taattctacc tcaccaatta tatacttgcc tgaatttttt aatttcaata tgaatggtag
    48241 gtctagtggt acacctggag acactacaac catatctata tcatctacat cttctgggtg
    48301 atgtcctaat atgtatttta tgtcatttat agatttcaat tcatcaagta tatttctcaa
    48361 tttattttca tcttttatat catttacgat tatacttgca cccaatttat ctaaatgttt
    48421 aattgtagat ataccagttt ttgcaagtcc tactaataaa actttttttc cttttaagtc
    48481 catttttcat tccccctagc cctaaaatac tgctattata cttatccaag ctaaaacaac
    48541 tgttataatc caaaaaataa atacaactct tgtttctggc caaccacact gttcaaagtg
    48601 gtggtgtatt ggagccatct taaagaatct ctttcttgtt gccttaaaat atccaacttg
    48661 aatcaaaact gatagagcct ccgcaaaata aattcctcca attataggta ttataagcac
    48721 tgagttagtt agaactgaaa atgctacaac tgcacctcct aatgccattg aacctgtgtc
    48781 gcccataaac actctagccg gatatgaatt aaatcctaag aaacctaaac atgctccaac
    48841 agttgctgct gctaaaactg cgacttctgt atttccagca atagaacttg caaatagcat
    48901 aaagaataca gaaactatta atgttactcc tgatgctaat ccatctaatc catcagtcaa
    48961 gtttacagca tttactattg ctacgattat aaacatcatt attggtatat ataatattcc
    49021 aacatttatc acaaaatctg taaatggtat cataagttgt gaagcacttg atgatgatgt
    49081 atactgataa aaagcaacat aaaaagataa tgcaacttga aggattattt tttgatatgc
    49141 ttttagtcca agtgatcttt ttagctttat ttttataaaa tcatctaaaa agccaataaa
    49201 accaaaacct gcaatacata taagacctac tgccatatca tgactaactt ttactcttgt
    49261 aagtccagtt attagaattg caacaatcat tataattcca cccatagtag gtgttccgtt
    49321 tttagctaga tgtgtttggg gtccatcatc tctaactgtc tgaccaaatt taaattttct
    49381 aagcattggt ataaatattg gtcctattat aattactatt aaaaacgcaa tcaatgcggt
    49441 gtacgtaagc tctgttattc ctaacatcat aaaactcctc tcccttgtca attaactcat
    49501 tagtttaagc ttatttattt agatattcga ctattttttc taatctcatg cctcttgagc
    49561 cttttactaa aatagtgtct cctgttttta ctaattcatt taacttgtta aacacatctt
    49621 ctctattctc aaagtgatat atattggctg aattgaatcc taattgtttt gcttcttctc
    49681 caataaacac tgaattttca cctatagtta ttataatatc agtattattc atagatgatt
    49741 ttccaactaa tctatgacca tactctgaaa tttcacccat ttctagtata tctccaagta
    49801 tcgctaccct tctaccttta tatcttccaa gtatctttaa agcagcatcc atagaatctg
    49861 gactagcatt atatgaatca ttaattattg ttaatttttc attttttatt atgtctagtc
    49921 tcatttttgt ccctttaaaa ttttttaaac ctttttttat ataatctaaa gaaatattta
    49981 gacacaaacc aactaatata gcagacattg cattatatat attatgttct cctattgttg
    50041 gtataaatat ttcctctttt ttcccattta ttacacatat aaatgttaaa ctatcctctt
    50101 ccatagtata actttcacaa taaacatcat tgtttttatt aaagccaaat gtttttaact
    50161 tatatacatg ttctttttct tttaatgtag ataaaaactt atcatctcca tttacaatta
    50221 aagtatttgt ttcatcaaag tttgaagtaa tctccatctt tgctttcaaa ataccctctt
    50281 gtgaacctag tttttctaca tgtgataatc ctatattcga tatgactgca attttaggat
    50341 ttactatatc aactaaatat tttatttcat tgaatccaga catacccatc tctattacag
    50401 cacactcatg ttctttattt agattaaata aagtcaatgg aactccaaaa tgattattta
    50461 agtttttttc attttttagt atatttaact ttgcagatat ggcagagtaa atcatatctc
    50521 tagtagtagt ttttcccaca ctacctgtaa cacctataaa tggaatatca aatttttctt
    50581 tatagtattt tgaaatatct cctagagcca aagatgtatc ttttacctct attaaattta
    50641 tatccgaact ttctaatttt attccattac tttcattttt tataaaagtt ttacatccac
    50701 tatcatatgc agacttcata aatgtatgcc catctaaatt ttctccaact atggctacaa
    50761 atgcattttg ggcatttgcc tccctgctat ctataactat atcacttaca cagtcattat
    50821 aatctccata tattaacttc ccattagttg caagtactaa ctcttttatt gttaagcact
    50881 ccattattaa actcctcctt taaaacctta gctatattct cttagcaaca aaaggcaatg
    50941 tataccgtta tatatacatt gcctacgata actcttaact ttataattat atactatatt
    51001 tctgtttttt tgaagatgtt tatgggtata tgttaattat ctgttacttt ttagttttca
    51061 aaatataggg ttatacttga gtcttcatta acttttactc caggttttgg gaatatatcc
    51121 tttacctttg tatcttctgg aagttctata tctgcatcta agtctggttt taacttcgca
    51181 tcctccaatg cctttacagc atctcctatt tttagatttc ttacatctgg cactttaact
    51241 tgcttctttt catactcagc tttttcttct tctttatata ctggtttaac tcccaaatat
    51301 tttaaagaat cattcattat ttctttcact attggtcctg ctgtagtact accaaatgca
    51361 cttactcctg ttggttcgtc aacaatagca agaactacta tttgcgggtc atcacaaggt
    51421 gctattccaa caaatgaaca tatatacttt cctggagcat acttaccatc tataactttt
    51481 tgagctgtac ctgttttacc accaagtcta taacctggta tatatgctat ctttcctcca
    51541 ccttcagtta caactgattc tgcaatttct aacatttttt tagatgtttc tttagatata
    51601 acacttctta ctttttttgg ttttactgtt tcagttatat ttcctttatt gtcagtataa
    51661 gattttacca ctcttggttg cattaaatct ccaccattag ctattgatga tatagctgtt
    51721 ataagttgta ttggagttac tgatatagat tgaccaaatg atattgtagc caattcaact
    51781 ggtcctacat ttttttcgtt atacagtatt cccttagctt ctcctggtaa atctatacct
    51841 gtcttatcca taagaccaaa tgattctata taatcataca tttttccaac acctaatctg
    51901 cttcctaact caacaaatac tgggttgcaa gagttttgta ctgcttgttt aaattcttgt
    51961 gttccatgag gtctgtaatg tctccaacat ttaatctttc ttcctccaac agttacacta
    52021 cctgtacatg tgaatttttc tccatcttta attactcctt cttcaagagc actggaagat
    52081 gtaataagct taaatgtaga acctggttca tatgtatcac ttactgctgg atttctccac
    52141 atttgataat agccttttat tttatcttta tcattatatt tttcaagttc ttcttgataa
    52201 tatggatata ttggcgttct tgagtcatta gggtcataat ctggttttga tgctaaagca
    52261 agtatatcac ctgttttagg gttcatagct attgcagtaa ctttttttgc attatttaac
    52321 tcataagctt tctgtactgc tttttcagta tagtgttgaa ttacttcatc tatagacaac
    52381 acaagaccat taccttgtac aggctcataa tatttttcca ttccttgtgg tatttctctt
    52441 cctgaagcat cagtacttac tataagtttt ccaggctttc cttttaactt tttatcatat
    52501 tgcatttcta caccagatat acctgttgca tctgaagaag tatgtcctaa cacatatggt
    52561 gcaaaattcc catatgggta atatctttga ttatcttctg ccacccatat tccacttaat
    52621 ttagcatctc ttatttgact tgccttatca tcatctatcc atctttttac ttttacaaga
    52681 gccatatttt ttttgcttat taaagcgtaa atatctttat aatcttcatc caaaatctca
    52741 gctacctttt cggctgcttc ttttttatct tctacttcca caggtttaca ccaaacagta
    52801 tacttagtta cacttactgc taactctttc atatttctat catatatagt tcctcttttg
    52861 ggttctattg gtatatctct tgtttgttgt tctagtgctt ttgtactcaa ccaatttccc
    52921 ttcataagtt gtagataccc agtcctaata acaaggcaaa aaaacaatgc acatgctaga
    52981 ataagaacga gtaccagcct tttcttactt atcctcttta cttttctcaa atctattccc
    53041 cctagttatc cacatctata tactttattt gtccatcttt tggatagtcc atattgagca
    53101 attccttagc ctttagctca atttctttta ttgatgtttt ttcagtttct tttgccttta
    53161 gttcctctaa tactatctct ttttttctta aatctttttg taaataatag atatcgtact
    53221 tcatttccga gatttttgaa taaccacata gattcaatat tattactgaa aaagttgcaa
    53281 tcagtaaaat gcatttagct cctatttttt tcttatttct ctttttataa ttattctttt
    53341 ttttattttt atattcattt agattatgta ttttataatt ttttttcaaa ttctcacccc
    53401 gatagtatat agtttaaatt ttcctctata ctatatttgt tattaatcat atttcttcct
    53461 ctaaaatttc atcgctaaat taatacacta ttacacaatc taattgtatt tttttctata
    53521 cacaacaaaa acctataaat tcacttatac ttttatatga atctataggt tagatattaa
    53581 tttctattta tttttatcac ttctagtatt tttagataat ttcttccata aatataatat
    53641 gtaactaact atctactctc tgattcctaa gttctccatt atattactta ataccatcta
    53701 tatctatatt tttatatcta aattttcatt atatatctca ataacaaaga acatttctta
    53761 tagtgttaat tgttttttaa ttgctttacc agtgcaacaa aatatataat actttttaat
    53821 taattataat aatcttatat ataagattat tctttagcct tataactact tatatttttt
    53881 ctgctactct tagcttagca cttcttgaac gtggatttac ttctatttct tcctcactag
    53941 gtaatatagg ttttctagtt attattttca cctcagattc tttatcacat tggcatatag
    54001 gtaaatgttg tggacatata caatctgatg ctaaatgttt gaatgcattt ttcactattc
    54061 tatcttctaa tgaatggaat gttattatac atattcttcc accttcattc attatagaag
    54121 aagcatcatt tatcatcttt gtaattactc caagttcatt atttacttct attcgtattg
    54181 cctgaaaagt tcttttagct gggtgaggtc catctattct agctttctta gggatagctt
    54241 ttttaattac atctactaat tctcctgtag tttctattgg tttgtttgct ctttcttcaa
    54301 ctataaattt agctatacgc ttagcccagt tatcttctcc ataatctttt attatcttag
    54361 ttaattcatc ttctgtataa gtatttacaa catcatatgc agaaaactca cacctaacat
    54421 ccattctcat atcaagtggt gcatcttgca tataagaaaa tcctctatca gcttcatcaa
    54481 gttgatgaga tgaaactcct aaatcagcta atacaccatc aattttgtaa actcctattt
    54541 tttctaattc ctcttttata ttttcaaaat tgctgtgaac aaacttcact ctactttcat
    54601 attcactcaa tctctctttt gctgtgctta tagcattttt atcttggtca aaccctataa
    54661 ataatccctt atctgacagt ttttttacta tttctttaga atgtcctgct cctcccatag
    54721 tacagtcaac atacacgcca tctggcttta tatttaaatt ctctatacac tcatttaaaa
    54781 gaactgatac atgatgaaat tccatagtta cctcccttaa attcactttt taaactattc
    54841 ttcactaata ttatttttat ttttctttga taaataaaca tgtgcaatta tgccaccaac
    54901 aactccaatt agacttataa cttgtgccat tctaagtggt cctaacatta aactatctgt
    54961 tcttaatccc tctataaaaa atcttcctat tgaatataaa gttatataag taactataac
    55021 ttgaccttca tattttttat tttttctaaa tagtaataaa actataaata ttccaaaatc
    55081 ccatatagac tcatataaaa aagttggatg tacctttact ccatcaacca ttattcccca
    55141 aggtaaattg gtagcacctc catgtgcttc tccattaata aaatttcccc atcttccaat
    55201 agcttgtgct aaaggcattc caagtataac tgtatcagcc atttttaaga agttaatatt
    55261 tttaatctta gtgtatatat aaccagctaa tattccacca attaaccctc catgtatagc
    55321 aagtccacca cctctaaaat taaaaatttg agacatattt tgagcatagt aactccaatt
    55381 aaatacaaca taatagattc ttgcacagat tagtccaact ggaattgcta ttatagctat
    55441 atttaataca tcatcttctt taattcccac tctttttgct tcttttattg ctattaaagt
    55501 tcctaaaatc attccacatg ccataagtat tccataccac atgatgtcta tgccaaacag
    55561 tgtaaatgct actctatcca taacgtcacc tctttgtatt aattgaaaat atttccaaag
    55621 caatatgcta taattacaat taattgtaat tatactaaat tatgataaca cattaatgtt
    55681 aattctacaa aaaatattaa aatttattct acaactccct acactatatt atatctaatt
    55741 actataaaat tttttaaact gaatctctca tgactaaagt tacaagtgta catagatatt
    55801 ttttaatcaa aaagattgat gcatatatac atcaacctct tctaattctt atctatagct
    55861 cttaaatttt tacctcaatt tatataaata tattttataa atttgtttta tcaaaataaa
    55921 catttaaaaa cataaactaa tacttaatta gttattctta ttatgattaa gtttctattt
    55981 aggctctaca atagaaataa cacaatactc ttctttaaaa tgctctttta atctttcttc
    56041 aacttcctca aaagtaatat ctttaataac atctaaatac tccaatagat ttatatcctt
    56101 aaaaacataa gatataaaac tattacctat aaagtttata gaatcaaagc acttaataaa
    56161 tgaccctatt tttttctttt tagttctctc aaactcttct tttgataatc cttctttttt
    56221 tgatttttct atataatcaa gaattatttc ttttactttt ttaggctctt tagaatctcc
    56281 agctattatg ctaaaagcat aatccacttg agacgaaaat ccagctccaa aattttcatt
    56341 tattaaacct tgcatataca aatcttcata aagcttactt ccttttttaa ataacatccc
    56401 tacaagtata tcagttacaa tctctttacg taaaagttct ttccctttta aaccaacatt
    56461 actatcttta aaacctatgt tgaacatagg catagatata gggaattttt ctataacctc
    56521 tttttctttt acaccttctg gttcttctgg ataaaatctt tctatactct tagagagttt
    56581 atctactttg taattgtttg actttttagt tacatctata actttttcta catctaagtc
    56641 accaacaaca aataaagcca tatttcctgg attatagaaa gtattataac atttatatag
    56701 ctcttcctta gttatcttat atatactatc aacagtacct gctatatcaa ttctagcagg
    56761 ataatttaca tacattgcct tcaagcaatt aaagtataca ttccaatcag ggtcatcatt
    56821 gtacattttt atctcttgtg ctattatacc tttttccttt tcaacatttt catctgtaaa
    56881 ataaggtgtt tgaacatagt caattagatg ttctaaactc tcataaaaat tttcagtagc
    56941 agaaaataag taggctgtca ttgtaaaatt agtaaatgca tttgcattta ctcctaattt
    57001 tgaaaattta tcaaatgcat ctcctccatc aggttgctca aacatcttat gctctagaaa
    57061 atgtgcaata ccttcattca ctctaatttt cttatcttct ccaattggta caaattctaa
    57121 gtcatttgaa ccataattag tagccaaaat agcatacttt ttcataaaac cccttttagg
    57181 cataaaatat acatctaatc cattttgcaa tttctcataa taaacttctt ctttcaatat
    57241 atcattaact attttttcca tagacatctc ctccattaat ttctcaagaa gtatacagta
    57301 tcaagctcta tattttttat agcttcaact atatcttttt ttgtaacctt ttctatacta
    57361 gatattatgt cttgtacttc agaatttgtc tttgccatag attgagagaa aacaaaatca
    57421 gacataccac ctatattatc agttatagat ttcatagaat taactaaagc aagtttactg
    57481 ttttctaatt cttcatcaga tatatcacct gcttttacac tttctacttg tttttttatc
    57541 aattctacag ctttatcata atctttagtt tctataccag atgatataaa catgatactt
    57601 ttatacttct ctattgaaga gaatatatag taacataaac tttctttttc tcttacatta
    57661 acaaataatt tagagtgtgg accaccacct aagacattgc tcccaactac taaagcataa
    57721 tatttatcta tgtctgcata atccacattt gctctataac ccataactaa cttaccttga
    57781 gttatttcca tttgttcatc tataactttt acctcatcca cattttttat aaaatctgct
    57841 cttggtatat ttataatttc ttctctttca aattttagat ttttacttat tatatctaca
    57901 actttatctt catcaaaatt accttctaca actatatcta taggtgatgt tttaagtatg
    57961 tttttataat gttcatataa ctctcttgaa gttatactat ctatttcatc ttcataacca
    58021 aattcactta cactatatct ctctccttta cacatagcct caatacattt atcttgcgca
    58081 tattcctttt tatcatttat tattgattgt atcttttctc ttaaattctc tttttcaata
    58141 tttaaatatt cttctttaaa cccaccatct acaacaagcg tattatttat tacttcatta
    58201 aaaaattcta ctacttcttc aaatatactc tcatctaaat acttttcact tatgttaatt
    58261 actttaaaac tcaatacttg acgttctcca cgttttacag catcagctcc catagatgaa
    58321 ccatataaat catctaattt attggatatt gctctagcac taggatattt agcgcttcca
    58381 cttgctatta ttgatggtat tagagcattt tttgtagttt ctttttcatc caatagtctc
    58441 tgaacatata aacttataag attcgattta aacttttctg tttttatcaa agtaagatta
    58501 atattattac ctaaatttat tattttttta gtattaacca tatgtacctc ctatttttat
    58561 ttaaacatca attttaaaat tgaaatttat ttatttttta attacatata ctcacatata
    58621 aaaaccttct atttaattat atccttttta ttattttcta aaagcaatat ttttatttaa
    58681 attaaataca aatattattt aaatcaatat gctttaaagt ctagtttaca agcttgatat
    58741 atatgatgta taatcaatat gtatgtctat aattaaaaca attttgcaat cctatagatt
    58801 gattgtttaa agttatataa agaatataaa aaagaataag agagaggacg attaatatga
    58861 aattaggtat agttggttta ccaaatgtag gtaaaagcac actatttaac gcaataactc
    58921 aagcaggtgc agaatctgca aattaccctt tttgtacaat agacccaaat gtgggagttg
    58981 tatctgttcc agatgaaaga ttaaacaaac tacaagaatt atataattct gaaaaaatag
    59041 ttcctactgc tatagaattt tgtgatatag caggtttagt tagaggagct tctaaaggag
    59101 aaggtttagg aaataaattc ttatcacata taagagaagt tgatgcaata gttcatgttg
    59161 ttagatgttt tgaggatgaa aatgttgtac atgtagatgg ttctgtagac ccacttcgtg
    59221 atatagaaac tataaactta gaattaattt tctcagatat agagattctt gaaagaagaa
    59281 ttaataaaac tcaaaaagct gctaaggctg ataaaacttt aggttctgaa cttgatttat
    59341 taaaatcaat aatgtctact ttagaagaaa gtaaatgtgt aagaactatg gaatttacag
    59401 aagatgaaca aacattcgta aattcattgg atttacttac atctaagcct gtaatatatg
    59461 cttcaaatgt atcagaagat gatttagctg ataatggaga aaataataaa tatgttcaac
    59521 aagttaaagc atttgcagaa acagaagatg ccgaagttgt tgtagtatgt gcacaaatag
    59581 aagcagaaat ttctgaactt gattctgctg aagaaaagaa agagttttta gaaacattag
    59641 gtcttgaaca atcagggctt gataagctta taaaatcttc ttatgcttta cttggtttaa
    59701 tttcattctt aactgctggt ccaaaagaag ttagagcatg gactataaaa gttggaagta
    59761 aagctcctca ggcaggagga aaaatacatt ctgatataga aagaggattt atcagagcag
    59821 aaacaatagc ctttaatgat ttggttgagc atggtactat ggctgctgct aaagaaaaag
    59881 ggttggttaa attagaaggt aaagaataca tagttaaaga tggagatgta atattattta
    59941 gatttaatgt ttaaaatgat taatcgtata cactttgact attatatata ataactaaaa
    60001 aactaagatt ataataatac aatattatct tataataatt atatagaatt taaaaataaa
    60061 agaagagtat ttcaaatgat ttgtataaat tattatgaaa aactcttttt ttgatataat
    60121 aaaattactt acatatataa tatttaaatt tataaattat atttttattt tttaaaatat
    60181 gtataacaca cctatagaaa ttactattat tactatctaa agtattttgc tataatccca
    60241 tatactctta cctcaaaaac attcaaatgt aaaaaatact acatattaat aaactttgcc
    60301 caataattcc taaaataata tcctaacaat gatttatgtt tttataatag tatattttta
    60361 cataaaaaag tgaacattga ttaacaaagt tcactttttt ataaattttt atgttataat
    60421 tcacaatttt atttaatttg tttcttttct atttaaacta tatctatcta atattaattt
    60481 ttcatattct tctattggca ttggtctagc aaataaaaat ccttgggcca tatcacaacc
    60541 tataaacctt aaaaactctg cttgctctac agtttcaaca ccttctgaaa caacttttat
    60601 atcaagttgc tttgccattt gaacaatact tgaaactaca atttgactct tttttgcatt
    60661 tcccactgtt ataaagaatt gcctatctaa tttcaataca tcaattggca tatctttaag
    60721 catatttaaa gaagaataac cagaaccaaa atcatccata gaaattttaa atccaacaga
    60781 tttcaaagtt tgcattattt taaataatat ttttgtattg tcaaatattg cactttctgt
    60841 caattcaatc tcaattaaat ttggttcaat ttcatattct tttgttattc tttcaagctc
    60901 agaaataaag cctggattct caagatgtac tcttgataag tttattgata taggaaatgt
    60961 ggggaaattt tcattttccc aacgtttaaa atttttacaa acttgggtaa atacaaacat
    61021 atccaattct gttataaaac catttttctc aaaaatagga ataaatacac ctggacttat
    61081 tagacctttt ttgggatgtt gccaacgtac aagtgcttca gcacctacaa ttttagtagt
    61141 tgataaatca accttaggct gtaaataaac tttaaattgt tcatttttta aagcatcatg
    61201 catttcttgt tcaatatcac gttcttctat gagagtttct tttaaatttt cagcataaat
    61261 ctcataaact tttaaatatt ttctttttac tgtagttttt gcaatcatag ctttgtcaag
    61321 acaggtagaa atatttgttt ctccctcttc aacaaaatat acacctatgg atggaattaa
    61381 attgagttct actcccaaac ttgtttttat cattgacaat tttttacgta taagttcaca
    61441 tatttctata attgactctc tattattttt cttttcaaat attatagcaa aattgtcatt
    61501 tgaaattctt gaaaatacag attgctcttt aaatatattc ttaattatct ctgctatttc
    61561 ctttaatact ctatctcctt cttcataccc aaacctatca tttactagct taaacttatc
    61621 tatatcaaaa taaattaaaa ctagattctt tttctcatga gaggataaaa attttccccc
    61681 ttcaagatta aatttatttg aattgccaat acctgtaacg ttatctttaa aagcaaattc
    61741 ttccaatttt tccttactct ttttatgtat aaatagtata taaattgtta atgccgtaaa
    61801 gattataatc aagactacac atgctgataa tgtaagtttt ataatagcat atgatttctc
    61861 agatatagca gttttaggaa cttcagaaaa aagataccaa tcattgattc ctattggggc
    61921 ataacttaaa taatatcctt ttccaaacat actataactt aatgaacctg atttaaagtt
    61981 ttttatattt gacttcatat tgttgatact agattttgat attgaatcac ttctgccaat
    62041 gtaagaaaat aaattttctt tagtagagtt ggcgttttta ctgcttggat ttaaaacaat
    62101 atcaccatta cttctagtta tataagaata tccttttcca ttaaatgtag gtacagaaag
    62161 tattttttca tacaacttcg tactatgtgt ggcaaatata actcctttaa cctcattatc
    62221 tttataaatt ggtacagaat atacattaat attactattg gtatttttat catcttctat
    62281 tacatctttt aattttcctg ttataaccac ttctccttgc attgatttta agaaataatc
    62341 tcttttagag aagtcttcta tataaccatc tgtagtgtat gctgtaccat ttggtaaaat
    62401 aactcccatt cttttaaatg aactattaat agcttgtctt tttagtatag aaaggatatt
    62461 atctacttca aaagactctt ctccttcaat aaatattgaa attgactcta gtaactttat
    62521 atctccatta atttgttttt ttaacacatt gacgctttga tttgctattt ctgaaagata
    62581 ttgattcgtt tcttcaccta atgtcttatt caaccttgaa ccataaatca aacaggaaat
    62641 tgtaattact aagatactta tgacagcaat tatggacaaa ccatacctat tattttttgc
    62701 atcacttaac attatgcttc ctgcctttct cgaatctatg tatgtataat cattatctta
    62761 tgacaattat tgtaaacatt ttataataat acttattttt ccatatttac tgtaattata
    62821 caaaattata aactttatta caacaataaa ttaattaata tagatattag tgtttacatt
    62881 attgcattat ctattttaca attatttaca tataaaaaaa tgtaatatca aagtgaagct
    62941 tgatattaca tttttgttct tgtattttgt ttaattttta tgctacatct tacttaaaca
    63001 ctcatttgca acttctttat catcaaaatg atgcttaact ttacctataa tttgataagt
    63061 ttcatgtccc ttacctgtta taattacaac atcatccttt tttgccatac ttatagcttc
    63121 tgctatagct tgttctctat caacaacaac atggtaattt tcttttttct tgtcaattcc
    63181 ttcaagtata tcttttatta ttgcctctgg ttcttcagtt cttggattat cagaagttat
    63241 aatacataaa tcagaatatt tttgtccaat tgctcccatc aaaggtctct tttcagtatc
    63301 tctatctcca ccacacccaa acacagaaat tatttttcct tctgcaaatt gttgagttgt
    63361 ctttagtaca ttttcaagtg cgtcaggagt atgagcatag tctacaatta cgcttatacc
    63421 tttatcattt ggaactgttt caaaccttcc tgatactcca ttagaaagtc taaggccttc
    63481 tttatatatt ggtttaggta tgccaagtac atagcaagca gctataactg ctaaagtatt
    63541 atatactgta aacatccctg gaactggtat aaatattact tcttcatatg aaggtgttat
    63601 taatctataa gatactccat ccgaatctga ttttatatct ctagccataa aatcagcctt
    63661 agtatcaaca ccataagtgt aacaaggtac atttatacct tttatatttt catatatctt
    63721 ttttccacct tcatcatcta tgtttattat atttgccata gtagtcttaa aaaataattt
    63781 ttcttttgct tttctataat cctctaaatc tttatgaaaa tctaaatggt ctggtgttaa
    63841 atttgtaaat atgcctagtt taaagtctgt ttcatcaact ctatttaatg ccaatgaatg
    63901 tgatgaaact tccattgcac agtagtcaca tccattatcc aacatattat taaaatgata
    63961 ttgtaaatct atactttctg gagttgttga attggaaaca atgtcttttt ctccatcaaa
    64021 aatttttata gttcctataa gtccaacttt attcttattt aaagttaata tctcatttag
    64081 tatagtagtt atactagttt ttccattagt acctgtaact cctataacgt taaatttttg
    64141 agatggatga ttgtaaaaat tatcagctac ttttgccata tcttttcttg tatcttttac
    64201 ctttataaat gtacatcctt ttattgctac atcttcttca acaagaaatg cacttgctcc
    64261 cttttctatg gcatctttta tatacttatg accatctgac acaaatcctt ttatacatat
    64321 aaataatgta ccttttgtaa cctttcttga atcatattgt acattattaa tatctatatt
    64381 taattcaccc ttgacattga ttatatccaa cccctgtata atatcattta atttcataaa
    64441 tgctttcctc cctttaaact ctttctgcta aaattacact acatataata ttatattaag
    64501 aattttttac tatgtgaatg gttaaaaatg cttgaaacat tgcaaaaaat gctctataat
    64561 tttctataat ataactgagg aaaggtcttc tataaaaact atggataata aaatcgggta
    64621 cttaaacgat aactttaaaa tatttaatat tagagataaa aaagatatac aatttgaata
    64681 ccataatcat gattttaata agataattat atttataaat ggaaatgtaa cttattttgt
    64741 tgatggtatt ccctataaac taaagccttg ggatatactc tttatcagca ataatgaaat
    64801 ccataaacca gttatagatt caaatgtctt ttatgagaga attgcaatat ggattagccc
    64861 agaatttatg aaaaaaaata gtgatgctag tagtgactta gaaaaatgtt ttaaaatagc
    64921 tacagagaat aaatgcaata gattgcgttt aaatatgcat gatattgaat ctattaagag
    64981 ttttattgag caaataaata tttccgaatc caatactgaa tttggaaatg aaatattgag
    65041 aaatacatta tttatacaac ttatgatatt cttaaacaga attttcctaa aaaatgaaaa
    65101 tatggaatca acagaagatg ttttttatga tgaaactatt aagaaagtat taaactatat
    65161 aaattcaaat atagatgata agctttcaat agatagcata tcgtctgaat tttttataag
    65221 taagtattat cttatgagaa aatttaaatc tcatactgga acgtctatac acaattatat
    65281 agttcaaaaa agattaattt tggcaaagtc actaataacc aatggtcacc ttatgagtga
    65341 agtttgtaat aaatgtggat tcaacgatta ttctagtttt gtaagggcat ttaaaaaaaa
    65401 ctacggtgta tctcctaaaa attatataaa caataaaaat cctttagata ttactctttt
    65461 agatgaatag ataatttatg taaattttat tttaataaaa cttgaagtat tagtgtattt
    65521 atcttactaa tacctcaagt tttttaatgt tttaaaatat atcaaaatat aatgatatat
    65581 atttctatta cttaaaatat atattaaata aattgcatgt taactgaacc tatttatata
    65641 tttattaaat ctcacataac ttttagttac actatcatat agctatccta ttttttcaat
    65701 atcatctctt aatatactta ctctattctc ctcttttgct gtggttactc cttttttaat
    65761 gcttaatttc tgattttgtt ctaaattcgt aaatactaca ggacttattg ttgatagacc
    65821 atttttttca atatattcta agtccatttt aactaatttt tctcccgctt ttacttcatc
    65881 tcctacattc acaaatactt caaatccatt tccttctaag tttacagttt ctatccctaa
    65941 atgtataagt atttctactc cacttttttg ggattttatt attattgcat gcttagttgg
    66001 aaatataact ccaatagttc catcaactgg tgaataaatc aatccatcac tagatttaat
    66061 tgcaaatcca tcccccatca gtttacttga aaatacagaa tctggcactt cttctatatc
    66121 taataactct ccatttgtta atgaatcaat cttttctact aaagtatttt ccatatttgc
    66181 aacttccata ttttttttca ctttattttt atcaacattt ttagtaacag tactttcaac
    66241 ctttgttttt ccctctatta tatcttttat atcagacttt attgaatctg attttggtcc
    66301 aaatatagct tgaacattgt tgccaataac cataacacct gctgctccaa gtgatttcaa
    66361 tttttcttta tctactttat ttatatcatt tacaaccaat ctaagtcttg ttatacacgc
    66421 atctagactc tttaagttgt ctttatttcc taaagcaatc aaaatctctg atgctaattc
    66481 attcttagac atttcaatga cttcagcgtt agtttctgac tcatcttctc ttcctggtgt
    66541 ctttaaatta aattttctta tcataaatct aaatacacta tagtataata ctgcaaaacc
    66601 aatacctacc aagatagcca agtaccatgg agttctatta ggaagaacac caaataataa
    66661 gaaatctatt aatcctcctg aaaatgtgaa tccaatttta actcctaata attgcataat
    66721 tgcgtatgat aaacctgaaa ataaacaatg tattgcaaat aatactggtg caacaaataa
    66781 aaacgcaaac tctattggct cggttattcc tgttaaaaaa gaggttaatg ctgctgatgc
    66841 cattatacct gctacaaatt ttttcttttc tggctttgct tcatgcacca tagcaagagc
    66901 tgctgctgga agaccaaaca tcataaatgg aaatgcacct gtcataaaag tacctgctgt
    66961 gaaatttact ccatctttaa gttgagcaaa gaatatcttt tggtcaccca ttacaagctc
    67021 accagcttta tttacatatt ctccaaattg ataccaaaat ggattatgga aaacatgatg
    67081 caaaccaaat ggtattaata gtctttccaa agaaccttcc ataaatgctg ctagtgtttg
    67141 atttgcttct ataacatttt ttgagaaact aagtaatccc tcttgtattg gaggccaaat
    67201 aaaagacaat ataattccta ttgctatagc aactaatgaa gtaacgattg gtacaaatct
    67261 tttacctgca aaaaaaccta gatactgagg taattcaatt ttataaaact ttttataaag
    67321 ataagcagcc actatcccta taataatacc accaaatacc cctgtttgaa ttgttggtat
    67381 tccaacaata tttgcataca tagaattgtc taccatatct tctgtaacac ctgccataac
    67441 acccatagat gtattgagaa ttaaaaaacc tactatggct gccaatgctg caacaccttc
    67501 tccttcagtt aaaccaacag ctaccccaac tgcaaatata agtggtaagt tattaaatat
    67561 aatttgacct gaactttcca ttatacttat tataagttga aatgtaggat tcgccaaagc
    67621 tggaaaatga gccaacaatg cgtctcctgc taaagcatta ctcacgccaa gtaatatacc
    67681 tgctgcagga agtaatgcaa ctggtagcat tagagatttt cctacttttt gtaaaacacc
    67741 aaatactttt ttcatttact tttctctcct tattatttta tattttttta aataaaaaag
    67801 acttaagttt ataaaaagtt acattagtat acttaattct aaaattaaac ttatgttaat
    67861 ataaacaaac ctatattaac ctaatttcag aattaaaaat aaactattat aattttttta
    67921 taaacataag tcttgcctgc attatcagta acaatcttaa tgttttaaaa ttattatttt
    67981 atattaaatt ttaaataata tattaaaatt aaacataata tattaaatct atacattctg
    68041 tattaaacta ctctttatta taaattcagt acagatataa ctcttttgat atgtaatgtt
    68101 aaataaagta gttcatcttg acttacatag taatcataat tcttttctac atgagttttt
    68161 attttatatg cacaatcata atccttttca tactttactt taattatatc tataatttca
    68221 ttatttgtat cattgatttt ttcttttttt actaatcgtt ttgcaaagaa ttttaaatga
    68281 gtcagaagcc tatcataatt tatatcatct tctttaaatt caactctata ataatatctt
    68341 ataatattta gtatgtcttt tacaatttta gtaattaaca gtgattcctt tgaacttccc
    68401 ttatagtttg aatttactat atgcattgct ataaaaccag cttcatctac tggaaatttc
    68461 acatcaaatt ctttatttat ataatctaca gcccatttcc caatctcata ttctttttta
    68521 tgtattcttt ttatctcatg tagtaaatca ttctttatag ttatgttttc atgatatctt
    68581 ttaattgcaa atgcaatatg gtcagtaagt gctacataaa tatattcata aagtttagta
    68641 ttcaaattct cctctgcata agcaattatt tcagtactaa cctcaaaaaa tttctcatca
    68701 acctggcttg ctagtttact aattttatct aaaaagcttt catcttgtat tacaaaagtt
    68761 ctttcaattt tacttttatc tatttcttga cctttctttt tttgaaaccc aattccacat
    68821 cctgttaata ttaattcttt ttttatattt tcatctaaaa ctaatacaac attattatta
    68881 taaatttgtt gaataatcat aatcaatatc tctcccaaaa tacaatttcc cttattcata
    68941 aaaaaatacc taaattaaga tacaattcac ctgtatacct taacctaggt attgcctgct
    69001 taccagtaac aatccagctt gttaacgctt atatattgta ttcaatttat ggttttattc
    69061 tattataaat aaatatatat gtcaagtaaa ttattgaaaa ctatttccta ttttttagta
    69121 ttaattttaa catcaaaaat caaattttat tccattatat ttatgattct atcatcatca
    69181 tttcatcata gagaatattt tccaataact ctttagccac ttctcttgat atttgcttag
    69241 tttcaactaa ttgttgaaca ctgtctcttt gactttgtat cgccattact ctgtagtatt
    69301 ctactcttgc ctcaaactta tcatcatttt gaatctttct agtaatccaa ttcaaataac
    69361 gattatagaa tctgattgct attaaggcct catgtctgtt atcttcatca gtatttttat
    69421 ttataaatga tatagcagtt ttagtagaaa gtgcatatgc atggtgaaac tctttgatta
    69481 tttctttatt ctcagatact atttttgtaa ttttttcttt tacttctttc tttacttttc
    69541 tatttataat ccacatgctt atttttaatt ttacaatttt aaatatagat ttttgaacag
    69601 attttcttga ttttgtaata taaaatctat acaatttaaa ggctctatca gaaattttac
    69661 catcttctaa tagtttcaaa acagctaata atccctgttg gtctgcttct gcaatcatca
    69721 tacttataag tttattatct ggagtattta gtattccttt ttctgagtct accaactgtt
    69781 catttaaatc atgtataact ggttgtactt cttgtgcttt ttcattacta agttttaaaa
    69841 tggcttcttt caaaattagt ttatatgcct ctttatcaga taataaaggt tctgactctt
    69901 gtacgttatt ttttaataat cttggcagta aaactgttgc caatactaaa cttataagaa
    69961 taacttctga tgatataaat aaaacagtat ctctcattgg aaatacatct ttatcagcca
    70021 aataaaaagg tatagataag gcagttgcta gtgtaaatgt accatgaaca ccacaagtag
    70081 caactattag tgagtattta catttagaaa tactctcttt tacaacttct tcatccttaa
    70141 aacctaaaaa acctacaaaa aaattattta aaggattctt tttaggtttt ataaaagaat
    70201 tatgccataa atatacccat ataaatctta taacaaataa aataagtaca attaaagtag
    70261 aaataaaagt caattccaat gccatatttt catttttact actaagtcct gtatatatac
    70321 ttggtaacaa aaaaccaagc agtgtaaaga caaatccatt caatacatac tccaaaacat
    70381 accaagtatt gtctgatatt atccttaatt tagtagttgt attttgtaaa tgctcttttt
    70441 caattccatg agctatccct gccattacaa cagctaggat tccagatact cctatttctt
    70501 ctgctacaaa atatacaaaa agtggagtca ttatttgtat aactattacc attggaattt
    70561 cttccaaatt ccacttgtgt aaactaagtc ttatttttat aattatgtat cctaaaatac
    70621 ttcctactat tattcctcca aaagctgtaa tcataaattg aatccctgcc tcttctattg
    70681 aaaaaactcc tgtaactgtg gcaagtactg caaccttaaa tgctactact ccagcagcat
    70741 catttaataa agattcacct tcaagtatac tcatcatatt tttaggaaaa tttaatcctt
    70801 gtgtaattga ttttactgct actaaatcag ttggagatat tactgctgcc aaagcaaatg
    70861 aaacagataa tggcatccca ggaataagaa aatgtataaa gattccacct gcaaacacgg
    70921 ttattaaaac taaaccaaat gcaagaagca aaattggttt tctgagctct aatagctctt
    70981 ttctcgatac attttgtcct tcactgaata gtaatggagc tatgatacat attacaaata
    71041 tttctggatt aaatgaaaat gagaatttaa atggcaaaat agacaatata atccctagta
    71101 caatttgata tattgcaaga ggaatattac tccacttttt gctaaataca gttgaaatcg
    71161 ttgtacaaac caataatccc aacaatgtta ctaaaattga cataactacc tctcttttca
    71221 ataataatat tatagattaa acttatatat caactaactt aatattaaca gcatgaaatc
    71281 ccatcttaat caaaaaaatt ttcagtttat tctattattc ttattatata catcaaattt
    71341 aatttttgaa atatctatac tagatgacat gcaacaaaat gatttattga tatttctttt
    71401 aaaactggaa tctctttttt gcatatttcc ttacaataag ggcatcttgt atgaaactta
    71461 catccacttg gtggatttgt tggagatggt atgtctcctt ttaatataat tctatttttc
    71521 ttaattgtag ggtcttgtat tggtactgcg ctcataagcg cttttgtata tggatgttga
    71581 gaatgtaagt aaagttctcc tttagttgca atttctatta tagaacctag atacataaca
    71641 caaactctat gtgcaatatg atttactaca ctcaaatcat gagatataaa taaatatgaa
    71701 agtttatatt tatcctgtaa atccataagt aaatttataa tttgagattg aatagaaaca
    71761 tctagtgcag aaacaggttc atcacaaact ataaattctg gatttaatgc taatgctctt
    71821 gctataccta ttctctgtct ttgacctcca gaaaactcac ctggttttct atttaaatgg
    71881 tacttagaaa gaccacaact ttctaaaaca tttaatatat tatcttttat ttcattcttt
    71941 ggcactaaat tatgttctat aactgcctcg gatattattt gttccacatt taatcttgga
    72001 tttaatgaac tatatgggtc ttgaaatatc atttgcattt tgggtcttaa ctttctaagt
    72061 tcttccttct ctaacttata tatatctaca ccattaaatt caactttacc ttcagttttt
    72121 tcaattaatc taagaatggt tcttcctgca gttgattttc cacatcccga ttctccaact
    72181 atagccaaag tttctccttt ttttaaatca aaagaaattc catctactgc ctttacacat
    72241 ttaatttcct tatcaaataa tccagattta acttcaaagt attttttaag accctctact
    72301 tttaataaac tctcttcttt tttcaattat atctcctcct ttttatataa ccaacatgca
    72361 atactatgac cactattcaa ttctattaaa ggaggtatct gagttctaca tttatcacat
    72421 actttttcac atctatcact aaaataacat gaatctggca tcccaattgg atttggtact
    72481 tgtcctggaa tcgaatacaa tcttttatct ttgttttttc caagagcagg ctttgatttt
    72541 agaagtccaa tagtataagg atgttttgga tttttaaata attcaacaac ctctgccact
    72601 tctataattt tgccagcata catcactaat actttgtcac acatttctgc aactactccc
    72661 aaatcatgtg taatcatcat tatagatgtg tttaattttt cttttatatt tttcattata
    72721 tctaaaatct gagcttgaat agtaacatct aaagctgttg ttggttcatc agctataagt
    72781 aattttggat tacatgataa agccatagct atcattattc gttgtctcat accacctgat
    72841 aattcatgtg gatatgaatt atatatttct tcagctcttg gtatttctac cagttttatc
    72901 atatcgatta cctttttctt agcttcttcc tttgataaat cttgatgtat cataatacct
    72961 tcaatgattt gacttccaat agtaaacgct gggtttaaag atgtcattgg ttcttgaaaa
    73021 atcattgata tctcattccc tcttattccc ataagttcat cttcattcat ctttaaaata
    73081 tctttgcctc gaaagattat ttctccacct tctatttttg atgttggaag taacttcatc
    73141 aaagacatgg ctgttacaga cttaccacat cctgattctc caactattcc aatagtttca
    73201 ccttcattta tattaaaatt tacttcattt acactcttta caatcccttt atctgtatga
    73261 aaataaactt ttaaatcttt aacctcaatt agtgctttac tcattatttt ctcctctcag
    73321 caaaattact taagataaca tacacctttt gattgtattt tataaaaatt taaattacaa
    73381 cattttctta cattttatta tttttttcta ttaattataa taatataata gttaatttct
    73441 atatatattg atttaataat gattactatt atacaataaa aaatatgtgt taaatattat
    73501 tttacggagg ttttataaga atatgaaatt taaaaaattg gcatcattaa tcttagtttc
    73561 atcattaatg cttacattta cagcctgtgc ttccaatgat aaagacaagt ctagtggaag
    73621 caaatctggt ggaactgttg taatacctat ggcaagtgac ccagatataa tcaatggagc
    73681 ttttgcaaac gttaaagaag actctcttgc atcaaatata gtttatgctc ctctttatac
    73741 ttatgaaaaa ggaaatttag taaattattt agcagaaaaa gtagatttta aagatagtaa
    73801 ggaattaact ataaaattaa aatccaattt aaaatggcat gatggaaagc caataactgc
    73861 tgaagatgtc ttatttacat ttaatacagt tttagacgaa aaacaaaatt caccatcaag
    73921 acaatactta ttggtgggtg agaaaccagt taaagtagaa aaaattgatg atttaacagt
    73981 taagattact ttaccaactg caagtgaatc tttcttatat ggtatatcta aaatttctcc
    74041 aataccaaaa catgtgtttg aaggagaatc aaatatagct aagtcagaaa aaaataataa
    74101 tccagttggt tctggtgcat tcaagtttaa ggaatggaaa aaaggtgaaa gcatagtatt
    74161 tgaaaagaat gcagattatt ttggtggaga acctaaggca gattctatag cgctaaaaat
    74221 aattcctaat gaagcatctc aagaagcagc tttaaataat ggcgaaattt cacttatgaa
    74281 gacatctgct gaaggatatg aaaaggcaaa atcaaactca aacttacaaa cttatactta
    74341 tagtgaagaa agattaaact acattgtatt taaccaaaat atatcaaaca tggctaacaa
    74401 agaagtaaga caagccttat catatgcctt aaatagaaat gaaatgatag aatcagcata
    74461 tggaaaagaa ggttctgtac ctgctaaatc tatattagtt ccagaagcag acttctatac
    74521 agaagaaggt gttgaagaat atgaccaaga tacaaataag gctaaagact tattggataa
    74581 aagtggtgtt aaaattgata aattaaaaat aggttataac acaggtagat ttgggcataa
    74641 aaactatgcc ttagtagctc aacaagagtt gaaaaaaatt ggtatagaag ctgaaatagt
    74701 tccttatgaa agtaaggcat tcttcaatat actatttagt aatagcactg aatgtgatat
    74761 gtatgtaaat ggttatgctt ggggattaga accaaaccca tatagaggta tgtttgaaac
    74821 tggtcaatat tgcaaccaaa ctaaatattc taatgctaaa atagatgctt tatgggaaaa
    74881 aggatttact gagttaaaca aggaaaaacg tgaagaaata tataagcaaa tacaacagga
    74941 tatatctaag gatgcgccta tttacactat agattatgaa caaaatttaa tggcagctca
    75001 aaaaaatcta aaaggaataa aagatgctaa accatctcct gcaatattat ttgaagattg
    75061 gtctaaactg tatgtagaat aattgatgta aaattttata ttattaatta gaaaaggaga
    75121 tgtctaaaaa taatattgtt ttattatttt aaaacgagac atctctttta attaggagaa
    75181 tttacttatg ttaaaattaa tattgaatag agtaaaagtt ttaataccta tgttaatctt
    75241 aatatctata ttatcatttg gacttttaga attagctcct ggtgacccag cagatgcata
    75301 tataaatcct ttaatgtctt cacaggatat tgaaaatata agggttaata tggggcttga
    75361 taaaccagta tatataagat atttaaactg gttgaaaaac actttaagtg gaaacttagg
    75421 tatttcttat ataaaccata tgcccgttac agaacaaatt atggaaaaaa tgggaaatac
    75481 atttattctt atgggtactt ctttgatatt ttcaatattg gtagctatac ctcttggaat
    75541 atttttagct gtaaataaaa attcaataac tagtaaagta tcatctgttt ttaattatat
    75601 aggtgtttct ataccttctt tttggatagg tatgatactc atttcaattt tttcagttaa
    75661 acttaacatt ttcccatcag gaggtatgca tactattgga aatgatagta ttggagattt
    75721 agtaaaacat ttagttttgc ctgtaataac tttaggtcta tataatactg ctatttttac
    75781 aaattatgta gaagctagtg taaatgaaca attaaaaaaa caatatgtta ttacagcaag
    75841 agcaaaagga ttatcagaaa aagtcatact atttaaacat gtcttgaaaa attcactgac
    75901 atcattggtt acaatcctag gcatgagtat acaaaaatta gtcactggtg catttgttac
    75961 agaagtagtt ttctcttggc caggtatggg aagattaatg attgattcaa ttttttcaag
    76021 agattatact gtaattatgg caataactat gttatcagca ctatttttaa ttttaggtaa
    76081 tttagttgct gatatactat acttattaat tgaccctaaa ataaaatcta gcaaaggagg
    76141 attctagttg tgtttacaag tatcttaaaa aaattaaaaa aagataaatc ctttgctttt
    76201 gcatgtatta ctcttagcat aataatcata ttaattataa cttcttttat attaaatata
    76261 gactctaatg caattgatac tacttctaaa cttcaagaac ctagcttaaa gcatatcttt
    76321 ggtacagacg aacttggtag agattacttc tctagagctc tttatggtgg aaggatttca
    76381 cttagtgttg gtattttatc aatgcttatt tctgtagtat ttggtactgc tgtaggtgtt
    76441 attagtggat atattggagg taagctagac caattcttga tgagattagt agatatgctt
    76501 atgagtatac ccagtttctt agttttgatt gtattaaata cttatctaac acctaaagtt
    76561 tccactatta tactaattat tggattctta agttggatgg aagtttcaag aattgtacgt
    76621 ggcgaaacat taaaaataaa ggaaaatgaa tactgtctag ctgctaaagc tactggtatc
    76681 aagactagaa atatactatt aagacatata gttttaaact taaaagagac tattgtagtt
    76741 gctggttcgt taaatattgc taatgctatc ttaactgaat ctgctcttag ttttttaggt
    76801 cttggaatcc aattgcctct tgcatcatgg ggtaatatgc ttcaagatgc tcaaagacat
    76861 atttttgaca agttatattt agctgtattt ccaggattac ttatattttt aacagtcatg
    76921 agtttgacta taataagcaa aaaattttct agtaatactt aacaaatttt atatagaaaa
    76981 taaaaacagt gattatctaa agatatacac tgtttttatt tttcgtttaa aaaaatacat
    77041 attttgtata ttataacttt aaatactact ctaccatgtt atgcaaagcg tattattgct
    77101 ctcaaacata tagatgaaaa actattagtt tattataata aaaattgatt tatttatttg
    77161 ttattttaat aacattttta agagttcttt ttactaaaga aatctataat aaatttaaat
    77221 acatgttggt ctacatggct ataacgttct tttttaggtc tacataatat aactttccat
    77281 gtaataggat gattaaaagg cttttctata attttgctat tttcaaaaaa atcatgaact
    77341 ggtgatggta aaattgttat aaaatcagaa tttgtggttg atagcaacaa aaaatcccat
    77401 gaaccagaca ttatatatct ttttaactta acattttcat cagtaaattt ttgcattagc
    77461 ttatgatgta tcataaaagt aggattaaat attgcaagta actgctcatt caaatcgttc
    77521 caatctatct tatccttctt agcaagtgga tgatttatat ttaaaaatgc tgtaagttca
    77581 tcttcttgaa gcacatgttc agttactaca cttttatcaa ttttatgtgg atgtaacaat
    77641 actgcataat ctaattcctg taagataagc attctattta agtcatatgc acccttctct
    77701 actatatcaa attctatatc tggattattt gcaactaact gtgcaactac atctgaaaat
    77761 actattccaa gtataagtgg aggtattcct attctaactt ttcctttaaa ttgaactgaa
    77821 tcttctctta aatcttccat catatttttg tattcattta tgatatgttc tgcatttaca
    77881 taaaatcttt ctcctgctgg tgttaaccca tttaacctgc ctttatacct ttcaaataaa
    77941 tatacatctt cactttcttc aaaatttttt ataatttgac ttaatgctgg ttgagatatg
    78001 tgaagtgtct tagatgctat tgataaatta aaaccagatt tcactatttc aacaaaatat
    78061 ttcaactgtt ttatatccat tttaaacccc cttccccaaa agtataattt agattatatt
    78121 ttttcttcta atgatatttt ataggaaaat caacataatt tcattaatat tttaacaaaa
    78181 tatttttcta aatctactat aaatttttat cctataaatt tttcttatac actatataaa
    78241 aaattagact tagacaaaac gcttttttcg ccgtaatcta taattagaaa caggaaaacc
    78301 taaagcatta ggaataaaag taattgaaat acttaaaaac aagcttgtat taaaaaagta
    78361 ctttattata gtgttcccta atttctttat tcagaaaatt tttaattatc attcaagaaa
    78421 ggtaactatt agatatgaaa gatgtagtaa tcgtatcagc agtcagaaca cctataggaa
    78481 gttttggagg tgtatttaaa aatacttcag ctgttcaact tggaactatc gctgttaaag
    78541 aagcgatatc acgtgtagga cttaatttat ctgaaataga tgaagtaata attggaaatg
    78601 ttcttcaaac agggcttgga cagaatgttg ctagacaaat tgctataaat gcaggtatac
    78661 caaattctgt tccaagctac acagtaaata aattatgtgg ttcagggctt aaaagtgtcc
    78721 agctagctgc ccaatcaatc acatctggtg aaaatgatgt ggtaattgca ggtggtactg
    78781 aaaatatgag ccaagctcct tatatcgttc caactgctcg ctttggtagt aaaatgggtg
    78841 acataaccat ggtagatagt atgctaacag atggccttat tgatgctttc aatcagtatc
    78901 atatgggaat aactgcagaa aatattgcaa ctaaatttga atttactaga gaaatgcaag
    78961 ataaattggc attagaaagt caaaataagg ctgagaatgc tataaaaaac aatcgcttta
    79021 aagaagaaat cgttccagta gatgttttaa tacgtcgagg aaaaatagaa actattgata
    79081 aagatgaata tcctaaatta ggtatgacat ttgaaggttt agctaaactt aaacctgcat
    79141 tcaaaaaaga tggtactgta acagctggaa atgcctcagg tattaatgat ggtgcggcta
    79201 tgttaatact aatgagccaa caaaaagcag acgaactagg tattagacca cttgctaaaa
    79261 taaaatccta tgcttcagct ggtgttgaac ctgaagtcat gggtactggt ccaatccctg
    79321 caactagaaa agcactgaaa aaagctggac ttagcatcaa tgatatagac ttaatagaag
    79381 caaacgaagc gtttgctgcc caagcattag ctgttaaaaa tgaacttcaa atagattcat
    79441 caaagttaaa tgttaatggt ggtgcaatag cattaggaca tccaatagga gcaagtggag
    79501 ctagaatact tgttacctta atttatgaaa tgcaaaaacg taaagttgaa actggacttg
    79561 caacactttg tattggtggt ggtcaaggaa tatcaatggt ggtttcacga taggaggaaa
    79621 tatgaataaa atagttagca ttgatgaagc tctatctcat gtaaaagatg gagatacaat
    79681 aatggttggt ggattcatgg ccaatggttc accagaaaat ttaattgatt atttatgtag
    79741 taaaaatata aaagatttga cactaatttg caatgatact ggctttattg acaaaggagt
    79801 tggcaaaatg gttgtaaata agcaatttaa aaagataatt gcttctcatg taggattaaa
    79861 taaagaaact ggaagacaaa tgaacaacaa tgaaacagat gttgagttag ttcctcaggg
    79921 aactcttgct gaacaaatac gtgcagctgg ttatggtcta ggaggtatac tcacaccgac
    79981 tggtattggt actcttgttg aggagggaaa gcaaaaaatt gttgtcgata gcaaagaata
    80041 ccttcttgaa aaaccaattt atgcagatgt tgctcttcta tttgcatcaa aggtcgataa
    80101 agcaggtaat ctagtttata aaggctctat gaacaatttt aataatttaa tggcatctgc
    80161 tgccaaaatt acaatagttg aagcagatga aatcgttgaa attggtgata ttgacccaaa
    80221 tgaagttaat acaccaggta tttttgtgaa ttacatcgtt gaaggaggta atttataatg
    80281 gataaattag aaatgcaaga atatattgca aatagagtat ctaaagaatt aaaagacgga
    80341 gccgttgtaa accttggaat aggtctacca accaaagtag caaattatat tccggataat
    80401 gtaaacgtta tcttacaatc tgaaaatggc tttttaggtt taggttcagc cgaagatgga
    80461 aattcaagtg atgaaactat tgtaaatgca ggtggtcaac cagttactat acttcctgga
    80521 ggatgtttct ttgatagtgc tacttctttt ggaataatta gaggaggtca tgttgatata
    80581 actgttcttg gcgcacttca ggttgacaaa tatggcaata tagcaaacta tatgattcca
    80641 ggtaagatgg ttccaggtat gggtggagct atggacctag taactggagc taaaaaagtt
    80701 attgtagcaa tggaacatac ttcaaaaggt tctgcaaaaa tattaaataa ttgtactctt
    80761 ccacttactg caacaaatgc tgtagatttg atagttactg aaatgggagt tatggaagta
    80821 acatcagatg gaattttact taaagaaata aatccagctt tcacattaga tgatgttatt
    80881 tctgctactg aagctccttt aatattgtca gattcattaa atggaaaaat atctgttgtt
    80941 taaaataatt aaaactagaa aataaaaatc tcttagacgt attacatata aatttgtatt
    81001 gcttaaaata ttaatataaa aataaaataa aattggagga aatgaaaatg gttaaagata
    81061 aagttgtatt cgtaacagga gctgcaagtg gaataggtaa acaaatagct gaatcgttct
    81121 taaaaaatgg tgctaaagta atgttctctg atataaatca agaagcttta aataatacca
    81181 taacagagtt acaaaaaaaa ggttatgatt gcatgagtgt aaagtgtgat gtaactaagg
    81241 aagaagaaat taaccacgct atagacaaaa ctgttgaaaa gtatggcaga ttagatatat
    81301 taataaacaa tgctggactt caacatgttt ctatgataga agatttccca actgataaat
    81361 ttgaatttat gataaaaata atgctgacag caccttttat agctactaaa aaagcatttc
    81421 ctataatgaa aaaacaaggc tttggtcgta taataaatat ggcctcaatc aatggtgtaa
    81481 taggatttgc tggaaaggct gcttataact cagcaaaaca tggacttatt ggactaacaa
    81541 aagttgctgc tcttgaagct gccgattctg gtataacagt taatgcttta tgccctggat
    81601 atgtagatac tccacttgtc agaggccagt tcaatgacct ttcaaaaact cgtaatatac
    81661 cattggaaaa tgtcttagag gaagttttat acccacttgt accacaaaaa cgcctattag
    81721 atgttcaaga aattgccgac tatgctatgt tcttagcaag tgataatgct aagggtatta
    81781 caggacaagc ttgcttacta gatggaggat atactgcaca atagttatta tatttagggc
    81841 ttgaagaaag tattcttcag gtccttctac taaggaggga tatttatgag tattatcgcg
    81901 ccaattggta taattattgg tatcatagct attatatatt tttcagttaa agaaattcat
    81961 ataactatag ctgctccaat agcaacttta atagttgtta ttttaaataa aatggatgtt
    82021 gtaacatcaa tgctaggtgc tgacaaaaac aattatatgg gtgcacttgg aaactatata
    82081 atgagttatt ttgcaatatt cttattaggc tcaatacttg ctaaatttat ggaagaaagt
    82141 ggagctactg tatcaatagc tgattttatt ttaaataaat ttggctctaa tcatccttat
    82201 agagttttag ttgctatatt tatagtaagt tttatattaa cgtatggtgg tataagctta
    82261 tttgtagtta tgtttgcggt cattccactt gcaagaactc tatttaaaaa acttgatatt
    82321 tcttggaacc ttattcagat accactttgg cttggtattg caacaattac tatgactata
    82381 attcctggaa caccagccat tcaaaatgtt atacctattc aatatctaaa tacgtctctt
    82441 actgcagcta ctataccaag tattgtaggt agtataggtt gtgctacgtt tggacttgtc
    82501 tatatgaaat atgctctaaa caaaagtatt agaaaaggtg aaacttatgc aacttatact
    82561 tcagaattag aagaagaatc tttagataga gaattaccag gattttttgc aagtattttt
    82621 cctctattag cactcgtaat tatagctata actggaagta cttttggttc agaatttatg
    82681 aaaaaaaatg taatttacat agctttaata gttgcaattc ttttatctgc ttttttattc
    82741 cataaatttc tatcatctaa gatacagaca ttgagcatag gtgctagtgg ttctataggt
    82801 cctatatttg ctacatcttc tgcagttgca tttggagcag taataatggc tgcacctggt
    82861 tttgatgtat ttagcaaact tataatgtca ataccaggta gtccacttat aagtcttact
    82921 gttttgactt caacaatgtc agcaataaca gggtcctctt ctggtgcatt aggaatagta
    82981 atgccaaact ttgcagatta ttatttaagt actggtctaa atccagaatt aattcaccgt
    83041 gttgctacaa tagcttcaaa tatactaact atagttccac aaagtggtgt ttttcttaca
    83101 ttcttaagct tatctaagtt aacacataaa actggattta aagaaacttt cattgtagtt
    83161 gcagttggtt cactaatagc agaaattatt gtaattacat taggattact aatgtattaa
    83221 tataaaacaa attaaaattc ataatatgaa aggtggtgtc tcaaagtgaa ctttttactt
    83281 aatgagacac tctttttata tgaaataaca tatgcctatc atttcaacaa taaaaaaggc
    83341 cttatctcta ttttgagaca gacccttttt atttcttaaa gatttaaata attataattt
    83401 gttgctaata cgaaagcatc tactgaataa atttaaccaa ataaaaaaaa atttatcata
    83461 actataaatt tacgttatgg aattattata aaaatattat tttctctaac taagtaattc
    83521 catactatac aggcttttaa tacaaattgt caaacacact gaaatatacc tatttattcc
    83581 atatatatct tttttacata tctttacagt aaaaaaagtc ttaatcttat gttagtatag
    83641 attcacgggt aaccccctac actaaaggtt acaaatcagt aacattttta gaatttttag
    83701 attaagaggt gtttaatgat gagaagaaat ataccaacaa aattaaaaac tatattagct
    83761 ttaggagtgt taactttagc aacagcttca agtgctgtta ctgcaagtgc ttcatcactt
    83821 gaaaataatg taaatataag taacaaaagt ttagtatata gtaatactaa atacaagttt
    83881 tctgcaaaac caaattgttc tgtaaaacca gaacttaagc ctgataaaga taactcttgt
    83941 aaggataaga atcataatga caagaattgc aacaacacta ataaacctga ggacaacaat
    84001 aattcagact ctactaataa gcctgataac aataaacctg agtctaataa acctgaagac
    84061 aacaataatt caggctctac taataaacct gagtctaata aacctgaaga caacaataat
    84121 tcagactcta ctaacaaacc tgatgataat aacaactcag gctctacaag tgaaagtttt
    84181 tcagcttacc aaaaagaagt tgttgactta gtaaatatag aaagagctaa agctggatta
    84241 aatcctctta ctcttgattc ttctatatca aatgttgcta caaaaaaatc tcaagatatg
    84301 attgataaca actatttttc acacaattct ccaacttatg gttctccatt tgacatgttg
    84361 aaaaaatttg gaataagcta taagacagca ggtgaaaata tagctatggg tcaaaaaact
    84421 cctaaagaag ttgtaaatgc atggatgaat tctgaaggtc acagaaaaaa tataatgaat
    84481 ccaaatttca gtaaaatagg tgttggagta gcacaaaaaa gtggtggttc aatttattgg
    84541 acacaaatct ttgtaggata aaatactctt tttccataca tatcaaaaga gtatctctaa
    84601 gtgataaaaa acacaaatga gatactcttt tgtatctatt ttaaaattat caaatccaaa
    84661 tatacatact ataaatatta tttgttctct taattttagt gtgtagagca atatataaaa
    84721 agtattggca agatgaaaat ggaaaactta aaaagatatt taataggtaa aaacaggatc
    84781 ttaatatctt cataaaaaaa ggctgtctca aaatagagat aaggcctttt tcattgttga
    84841 aatgattaaa atatatttga tttcatacaa aaagagtgcc tcatgaacta aaaagctcac
    84901 tttgagacac tctcttttat caattctata taagcattat aatactttaa tattattcag
    84961 ctaatttttt gtatccttca tatctttctt tagcatcagc ttcagcttta gcaaataatc
    85021 catcagcttc ctctgggaat tgtttagcta tagcagaata tcttacttgt gcaagtatga
    85081 aatctttgaa gcttgcagtt ggttcttttg aatctaaagt gaatgggttt ttaccttcag
    85141 cttttacttc tggattgaat ctgtataaat gccagtatcc gcaagcaaca gcttgtgctt
    85201 cgttagctac agttcttccc ataccttctt ttaatccatg gtttatacat ggagcataag
    85261 ctattattaa agatggccca tcatgttttt cagcttctat aacggctttg ataaattggt
    85321 ttttatcagc acccatagca acttgagcta catatacgtt tccatatgtc atagccatca
    85381 ttcctaaatc tttctttcta gattttttac ctgaagcagc aaacttagcc atagcagcag
    85441 ctggagtagc tttagaagct tgacctcctg tatttgaata tacttctgta tcaaatacaa
    85501 gtacgtttac atcttcacca gatgcaagaa catggtctaa tccaccgtaa ccgatatcat
    85561 atgcccaacc gtctccacct agtatccatt gagatctctt aactagataa tcttttctat
    85621 cttttatagc ttttactaac tctttagctt tttcatctgt acaatcacaa gctggttttt
    85681 ctaataattc aacaacctta gcacttgcta ctttagaagc ttctccatca tttctagaat
    85741 ctaaccactc tgtaaatact gctttagcat cttcacagat acccatagaa actaactctg
    85801 tcatagcatc tactatttta tttcttattt gcttaacagc tgtgtacata ccaaatccat
    85861 attcagcatt atcctcgaat aaagagtttg cccaagatgg acctttacct tcatggttac
    85921 aagtataagg aattgatggt gcagaagctc cccatataga agaacatcca gtagcattag
    85981 ctatcatcat tctatctcca tataattgtg taactacttt aatgtatgca gtttctccac
    86041 atccagcaca tgctcctgaa aactccatta atggttgtct aaattgactt cctttaacag
    86101 tgtttacagg cataacatca ccttttggag ctacctcatc aggatttact gcaaatgccc
    86161 aattatctaa ctctgtatca agttgagtat ctattggctt cataactaaa gctttttctt
    86221 tagctggaca tatgtcagca cagtttccac atcctgtaca gtcaagtgga ctaagttgca
    86281 ttctatattt taatccttct aatcctttac ctaatgcttt tttagcttca aatccttctg
    86341 gagcattagc taattcttct tcagtaacta atactggtct tatacatgaa tgaggacata
    86401 taaaagaaca ttggttacat tgaatacagt tatctattat ccattcagga acatcaacag
    86461 ctataccacg tttttcataa gctgcagtac cacaagggaa tgttccatct tctataccat
    86521 tgaatgtact tactggtaag ttgtttcctt cttgtgcagt cattggtctt agtatatttt
    86581 ttataaattc tggttcttta acttctcctt tatctgcatc aacagcattt tcccaagaag
    86641 ctggaacttc aactttaact aaagcattta ttcctgcatc aacagcagca tagttcatgt
    86701 taactatttt ttcacctttt ttaccataag ctttaactat agaatctttt aagtatttaa
    86761 cagcatcttc ttctggtatt atttcagcta atttaaagaa tgcagattgc attatcatat
    86821 ttattctgtt tccaagacct atttcttgtc ctagtttaac agcgttaact gtatagaatt
    86881 ttatatcatt tttagctata tattgcttca tatgagctgg taaatgttct tcaagtcctg
    86941 cttggtccca tatagtgtta agtacaaatg taccaccttt tttaagacct tttaataaat
    87001 catattgata aacatatgat tgtttatgac aggcaatata atcagcttca tctattaaat
    87061 aagtagctct tattggagta tcaccaaatc ttaagtgaga catagttata ccaccagatt
    87121 ttttagagtc ataatcaaag taagcttgag catatttttc agtatggtca ccaattattt
    87181 tgatagcttg tttattagct ccaacagtac cgtcagaacc taatccccag aacttacatc
    87241 ttatagttcc tttagaagct atttttattg gctcagatgg agttaaagaa gtattagtta
    87301 catcatcaac tatacctact gtaaatccat ttttaggttg ttctgaaact aagttatcaa
    87361 aaacagtttt tatatctgaa ggagtagtat cttttgaacc taatccgtat cttccaccta
    87421 ttatcatagg agcattttct tttccataga atacatcacg tacatctaag tataatggtt
    87481 caccagttga acctggctct ttagttctat caagtacaca tattctttca acagtagatg
    87541 gcatagcatc taagaaatgt ttcattgaga atggtctata taaatgaact ttaactaaac
    87601 catatttttc tcccttagca tttaagtaat ctatagtttc ttctattgtt tctgttactg
    87661 aacccatagc tattaatacg tatttagcat cttctgctcc atagtaatca aataaactat
    87721 gttttctacc tgttaaatta ctcatttttt ccatgtattt ttcaactata cctactatat
    87781 tttgatagta tttattagaa gcttctctag tttggaaata tatatctggg ttttgagcag
    87841 taccacgagc aactggatga tttggagata aagcattatc tctaaatgct tgaactgctt
    87901 caaagtttaa taaacttgca taatcttcat tttctagtaa ttcaactttt tggatttcat
    87961 gtgaagttct gaatccatca aagaaatgta taaatggtaa tctaccttct attgcagcta
    88021 aatgtgcaac aggtgctata tcagctactt cttgaactga accagaagct aataatacac
    88081 atccagtttg tctagcagcc ataacgtctt ggtgatcccc aaatattgat aacgcttgag
    88141 atgctaaagc acgagcactt acatggaata ctcctggtaa taactctcct gcaactttat
    88201 acatgttagg tatcattaat aataaacctt gagatgctgt aaaagtagaa gttaaagctc
    88261 ctccttgtaa agaaccgtgg aatgttcctg atgcacctgc ttctgactgc atttcaacaa
    88321 cattaactgt ttgtccaaat atattttttc ttccttgtga tgcccactca tcaactactt
    88381 cagccatagt tgaagatggt gtgattggat atatagctgc tacatctgta aacgcatagg
    88441 caacatgagc tgcagctgta tttccatcaa gtgttttcat aaacttagcc ataatatgta
    88501 tcctccttga tagctacaat tgtacttgtt tataacaagt ctattttttt atatttacat
    88561 ataatttaca caacaaaact ataaacacac atatagtcgc gcaaatactc tatcttctaa
    88621 tataatacta cagattagat aaaattcctt tgaaaattgt aaattaatta catatttaag
    88681 tagatttttt ttaaaattaa atatgttaag tttttttcat aattttgtat acaatatata
    88741 ataaattaag ttagattttt caaacttttt tatctatttg ttcatattag tataaaaagt
    88801 aaaatgctta tccttattac atgtaaattt ttatatatat aattttacca tattacatca
    88861 tatttttgta agtttttatt acatttttta taatacccct ttattttata aattaatcta
    88921 atcgattaaa tttatcctat agaaatttat tacatttaaa aatatgctag caaataaaat
    88981 atctactagc ataaagtcta tttataatat taatcaacta ttaattctac taaatctcca
    89041 tttttaacgc ctgctgcatt tccctcttcc atatcaacat gcatttctag attaaagctg
    89101 tcactagctc ttactaatac attttcaaat actaatgctc ttggtccaga tgttttaact
    89161 tttactattt gcttatcagt tacaccaaat ttagcagcat cttcattgct catatgtata
    89221 tgtctagaag caactataac tccttctttc atttcaactt ctccagcagg tcctactaat
    89281 ttaacacctg gagttccagc tatatcacca gattctttta ttggtgcttt tactcctaat
    89341 gggaaaccat ctgctaaaga tatttcaact tgagtatgag ctctagctgg tcctagtact
    89401 ctaactcctt ttaaagttcc ttttggtcct actaaatcca ctttttcttc acaggcatat
    89461 tgccctggtt gagataatgg tttaaattta gttaactcat gacctgcccc aaataatacg
    89521 tctatatcag cttgactcaa atgagcatgt ttattagata atgctattgg taatttcatt
    89581 gaaattccct ccttttaatt atttaaatta ttgcaataca attatacata atattaccta
    89641 caaaatcaaa ttatattgaa tcaatatata tctttaaatt tttatatatt atatctttaa
    89701 attcttgatt atctatataa gatacatcat ctgtattgtt taaatatata ttgtgtaaaa
    89761 gtttagtatt tatactctta aagaaaaaat ccatcacaat ctgtccacct ttaaactgtg
    89821 aatcatatga tttactcccc cccactgcaa tatacattcc tatccgtttc ttacttctat
    89881 caattgaagg tttatttaat acatatttac ttgcatatat agcttgagtt ctatcaacaa
    89941 cagtctttaa tttagctgat attgaatcaa aatgtacagg acttattact atagttcctt
    90001 ttgaatcatc aaacatttta tataatggct tcatatcatc attaaacttg caataccctg
    90061 ttttttcaca aaatccacat gctgtgcaat attcaatatc catattgtag atattaaata
    90121 ttttacaact taatccacac tcttctagca tagcttttac ttcatttgct ataaaactgc
    90181 aatttttatt aattcttgga cttccattta ttattataat ctctggactt ttaagtcctt
    90241 ttttatcgtt tgaatccata atcaatctac ctatccttta acataactat taaaatatca
    90301 tcatcataat tatcttttga tgagaagttc tttaaatcca attttagatt ttctactatt
    90361 aactgttgat ttaatctaaa attttctttt agaaagtttt ctaatcggtt tataccatac
    90421 tcttcttttg atgaattttt tatctctaaa attccatcag tgtacataca taccattgca
    90481 taatcttcca ttgaaagagt attattttca taagtagcat cttccattat tccaataggt
    90541 atgccctttt tacaatttaa attattttct attgtgccat ctttctttac aactacagga
    90601 ctatagtgac ctgcattaga cacagtaatc atattttctt tagtatctat aatacctatc
    90661 aaacaagttg taaatactcc catcttgtca aattcatcat ataacatcct atttaaattt
    90721 gtcattattt ctcttggtgt attgtattga ttgcataata ctttaaaagc accttttatc
    90781 attgcaacaa cataatttga taccattcca tgtcccatta catcagcaac aatataaact
    90841 atatgttcgt catccacttt tgtagcataa taaaaatctc cacctactac ccttgctggt
    90901 ttatggtaaa aataaagttc tttctcatca ttacaatcca ttttaccttt atccataata
    90961 agctgttgtt gtttatttaa tatgttcaac tcgttttcaa gaactttgtg ttttacttcc
    91021 ttttcattat gttcatataa ttgcatacca acagaaactt gtttggacaa tatactaaga
    91081 atatttaaat catcactagt atagtttttg ctatttgcac aaactataca tcctatagta
    91141 tcatttttat cctgaagttt gtaatatata taactttcca aatttattcc cttttttgag
    91201 catggtttta aattatttag ataccccccc aatgactctt tctttaaaaa catatcaatc
    91261 ataggatata aatttgtttt ctttttttgc tcaacattat aacaactaac tatagcatcc
    91321 ttattatgat gactatttat aattattaaa gcttctttac tattagtaat attacacgct
    91381 tgtttactta aattttccaa aaagccatca atactcttat taaggtatag ttttttagta
    91441 gcttcattta tggcacttat tgagcctctt agtttatcaa ttaaaatttg tacattatta
    91501 tttttattag ttatttctat tgataaactt aagagtgatg caacagatga tataaaatct
    91561 atatcttgtt ctgttatata atcatcctct tttaaaaaac aagtcataaa tccaacaact
    91621 acgttattta ttataaaagg aaaaactatt ctcccaatat aaccttcagc ttttgctaaa
    91681 tctcgttcac cttctgctct agaatcttca aatacatttt ccacatatat tatctttttt
    91741 tcatttacag cctcatgtat atactctgga tatgtgtcaa aatcaatttt tgcaccttta
    91801 agactattta ttggaaaaat ttgaggtaca tattctaagg tttgcgaaca tactaagtag
    91861 gcatatttag aatcattttt ataaaataga ttcacacatg cctttgtagg gtgaacaact
    91921 tctaacattt tttctattat gtcatctttt atattaaaaa aatctgtaga ttcagtcacc
    91981 atagcggata tttccactaa attcttcatt ttataactgc cattagtcat actcaatttc
    92041 tccccctata tattaaacta tttattagta ttttaacata cattctttat agtaaaaaca
    92101 aaaacaacga caaaactagc aactaatatc cagttaaatc ctgtcaataa tcctataaga
    92161 agtaatgtaa ttaatgcatt tagacctgtt ctcccttttt catccataaa agttatttta
    92221 gagatgtcga tattattttt cacattattt atatgctctt tcacttgttc ttccatattt
    92281 cttttatata gtatataaac tacaccaact aaaaacactc ctatacctaa aaccatgttt
    92341 aaattaaaag ctaccataag caatattgaa ccaaaagcta actttaaaag cttaaaaaat
    92401 acactatcta tctttagagt tatatttctg atttctttac attcatctct taaagaatat
    92461 ccacttgaat ctaagttatt aatctttgtt tttacaattt cagaataaaa aagctttatt
    92521 atcccattta acattttcat cactcctaaa tattttacat atatttgtaa gttttacaat
    92581 tataatattt tttatacttg gtaataataa aaaataacaa atattttatt atttagtatt
    92641 tattgtaaat aagttattga agcttgatta gttaagtata gattttt
//
LOCUS       DAFAZV010000014        90260 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFAZV010000014 DAFAZV010000000
VERSION     DAFAZV010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 90260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90260
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.014"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..819
                     /locus_tag="KOU88_001457"
     CDS             <1..819
                     /locus_tag="KOU88_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK3211357.1"
                     /translation="IGKYKIQDLHPVHIQNYIDKLSYKLNPQSIKIHINILKLAIKRA
                     YRLKLIKENVMDSIEAPRYKKFKNEIYDREQMIKLLDLAKNTEMELPINLAIGLGLRI
                     SEVLGLTWDNIDFEENTITVNKITSRINGSVILKEPKTESSVRKISSPKELMSLLKEY
                     KIKQNKNLLKSSIRNNNNLLFFNKKCEPIAEDVMSKKFKRFLEKNELPHIRFHDLRHS
                     HVTLLINSKVPIKVISERVGHSNISTTLSVYSHVLKEMDKEASDKISESLFNAN"
     gene            complement(1027..1503)
                     /locus_tag="KOU88_001458"
     CDS             complement(1027..1503)
                     /locus_tag="KOU88_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211358.1"
                     /translation="MVKKRLVAVVLSLAMISVGNFSYAHSGGHNSSGGHHNKNKSELT
                     RYYCGGHSAHQHNKGFCPYASTKENSGVTISSVHNEKNHKNYFAEKGYNKGYEDGCKG
                     LYNLSVTEAKSDNLYEKEILKSSYEKGYLIGYNEYKAKKVDDVMKKMLDIPMLASI"
     gene            complement(1702..3327)
                     /locus_tag="KOU88_001459"
     CDS             complement(1702..3327)
                     /locus_tag="KOU88_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3211359.1"
                     /translation="MLQVTGVGLRFGDKELFKDVNLKFTKGNCYGIIGANGAGKSTFL
                     KILSGEIEPNTGSISITDKERMSVLKQDHFEYEEETVLNVVIRGHERLWNIMKEKDAL
                     YMKEDFNEEDGIKAAELEGEFAELDGWDAETNAEKILMGLGITKDMHYKQMKELVGGE
                     KVKVLLAQSLFGKPEILLMDEPTNHLDFKSINWLNNFIMDLEESIVIIVSHDRHFLNQ
                     ICTNIVDVDFGKIQMYVGNYDFWYESSQLALQLAKDQNKKTEEKIAQLKEFIARFSSN
                     ASKAKQATSRKKQLEKLEVEDIQPSRRRYPYVGFTPAREIGNEVLEVHNLTKTIDGVK
                     VLDNVSFRLDRDDKVVFMGDEIATTALFNIVMGELEPDSGEYKWGVTTSQDYLPKNHN
                     KFFDGVEYSLVDWLRQFSEEKSESFIRGFLGRMLFSGEEALKEAQVISGGEKVRCMLS
                     KLMLSNANVLVLDDPTNHLDLESITSVNKGLEKFPGVLLFTSHDHEFISTIANRIIEI
                     TPNGIMDRKMDFDEYLESKEIQDQLAKMYGKDK"
     gene            complement(3665..4684)
                     /locus_tag="KOU88_001460"
     CDS             complement(3665..4684)
                     /locus_tag="KOU88_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-binding protein"
                     /protein_id="HBK3211360.1"
                     /translation="MKLIKTIDAVGQVLCHDITQIIPGEFKGRKFKKGHIVKEEDIPV
                     LLSLGKDNLYVWEKSEGMVHENEGALFLKELTAGENLDFSEIKEGKIDFIAACDGLLK
                     IDVDALFDLNCVGEIMMATLHNNFIVNKGLKVAGTRVIPLVIDEKKLEDAKKVVGNRK
                     IVNVVPFKPKKVGIVTTGNEVFYSRIVDKFGPVIEEKVKGFGCEVIGQTICPDDKEII
                     KSAIKEFISQGAELICCTGGMSVDPDDVTPTAIKETGADLVTYGSPILPGAMFLLAYY
                     GEVPIMGIPGCAMYHKTTVFDIVLSRVLIDEKLDKYDIARYGHGGLCMNCDVCTYPAC
                     NFAKI"
     gene            complement(4681..5250)
                     /gene="mocA"
                     /locus_tag="KOU88_001461"
     CDS             complement(4681..5250)
                     /gene="mocA"
                     /locus_tag="KOU88_001461"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBK3211361.1"
                     /translation="MINAVIMASGFARRMGANKLLLNYKGCSIIEHVFREVSKIDFHQ
                     VVVVSQYEEVLLLCNKYGFEYIDNKNANIGQSESIKLGVLNSSKCDGYMFFVGDQPFI
                     DNLYIDKIINTFKLDRDFIVIPRYKDMCGNPVIFPYSKKEELLALKEDEKGKTILKNS
                     SKIKYVEVPKEMLFDIDTKMDYERIGGKL"
     gene            complement(5357..6079)
                     /gene="yqeC"
                     /locus_tag="KOU88_001462"
     CDS             complement(5357..6079)
                     /gene="yqeC"
                     /locus_tag="KOU88_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBK3211362.1"
                     /translation="MELSNIIEKNEIITVVGAGGKTSFINYFANFYRDKLKVLLTTTT
                     KIYVPNDYDNIIITIDGTVIPSICHGITVCGSYINNENKLVSIDSSILDEIVDQFDLV
                     LIEGDGSKRKKLKGWNAKEPVVYHKTTKTIGILDITSFGMNINEENIHRVEIFKKIAN
                     LDTSSINSSSTVSIENLKNIVLNPNGLFKNYSGKRVLFINKVENEKYKNLAIKLIENI
                     KEYESEIEIFYGSVKQKFCVRY"
     gene            complement(6262..7539)
                     /locus_tag="KOU88_001463"
     CDS             complement(6262..7539)
                     /locus_tag="KOU88_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3211363.1"
                     /translation="MSNRIKNIHYGTQRQQLKNLTKKEYQALREMCFLAKNLYNVGTY
                     NVRQHYFNQGEHLNYEANYHVCKENENYKLLNSNIAQQILKEVDSSFRSFFGLIKLAK
                     EGKYDFRGIKSPKYLDKEGFFSIIIGQIRIKEDGILNVPMSPAFKKLYGKVSIKVPQN
                     ILEKKIKEIRIIPKHKARFFEIQYCYEIPKSEEVSNQKNALAIDLGLENLCTCVTNLG
                     DSFIIDGKRLKSVNQWANKQNDKIEALKLKKNITAITRKQFKVWNKRNNQVKDYVNKT
                     CFYIIDYCVKNNIGNLIVGYNAKLEKSDNMERKIYRNFIRIPFGEIKGKLEYLCKIKN
                     INFIRQEESYTSKSDFFADDFLPDINVDNVKKYDFKGERITRGQYKSSVGIIINADVN
                     ASLNILKKSQVVNLSNLQNNPQILKQPQRVRIS"
     gene            complement(7678..9984)
                     /locus_tag="KOU88_001464"
     CDS             complement(7678..9984)
                     /locus_tag="KOU88_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBK3211364.1"
                     /translation="MINKGIRKIDSTAIVTGKPLYTEDLIMHKDVLTLKLLRSPHAHA
                     KIKNIDTSKAEKIPGVVGIYTYKDVPQVRYCVPGQTEPEASPYDRVLLEDTVRFIGDE
                     VALVAAEDEKTALKALKMIKVDYEVLKPVFDAREAEGNEVVIHPEKDIVEPYPFGLDA
                     KNNIVSKEFFEFGDVEAKLKESDFVVESSYKTQSQSHCMMETHRSYSYKDINDRIVVV
                     SSLQSPHNVKRILRKVLGIPSSKIRVIKPRIGGGFGGKNIAATDIFTAFVTMKTGRPA
                     KFVFTRSETFVGSNSRHEMFFDVKVGADKEGNLKAIELKSLNNTGAYGGNGVSVSSES
                     GHNTLPIYNDIDAVRFNARTVYTNRLPAGALRGYGATQGIFAIDSAIDELAHKIGMDP
                     LEFRIKNIIDRYTNGKAAEDEILSCELRQCIEKGKKLINWDDKYPCKDIGNNKVRAVG
                     MAVANHGSGIPRVDMATVTIRMDEDGTYKLLSGLADLGQGADTIQAQIAAEALNTTVD
                     RISIYTGDSDLCPYDTGAFASCTTTVTGNATIKTANKLKDILLSVAESKLGFKKEDLE
                     LGKDRVFVKNDNSKFVLLEELGRESVGGIGFASDDVPVVLEATESFGMLKKIKPFIAG
                     FAEIELDKNTGEYKVINFACVPDCGTVINPTLARIQVEGGVMMGIGFAMYEDPIFDKD
                     GRLLTDSFLQYKVPTKKEVGNILVDFAENFDPGGPYGAKSLGEIVIHTPAPAIANAIF
                     NATGVRLRELPMTFEKVYMGMKNNNKQL"
     gene            complement(9977..10771)
                     /locus_tag="KOU88_001465"
     CDS             complement(9977..10771)
                     /locus_tag="KOU88_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBK3211365.1"
                     /translation="MVTIKEYSVPQSLEEAYKILISKKNNVILGGCGFIKLSNKNIGT
                     AIDLKDINLNYIKEDEKNILIGADTSLRSLEIDKTIKNYCSGILSSAVSNIVGVQFRQ
                     GARIGASVFSKYGFSDLIPALLVVGAKVRLYNKGILELSEFLDSELSRDILVEVILPK
                     KDAIAVFDSIRKCTGDFSVLNSAMLKENDTYKIAIGARPQKARLALEASNILNKEKDI
                     DKASIVASKELTYGSNMRASKEYRKDMASALVKRMYNAIEEGMYND"
     gene            complement(10878..12236)
                     /locus_tag="KOU88_001466"
     CDS             complement(10878..12236)
                     /locus_tag="KOU88_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBK3211366.1"
                     /translation="MKAKSTSKFELDGIPPLKEAIPLGLQHLMAMVIGSCLPAILIAN
                     AAGLNHKMSTLLIQAALVFAGLSTLLQLYPIPLFKGFKLGGGIPVIMGATAMFIGAGV
                     SVASKYGLPVLFGSQIIAGIVIIIIGFGLKKIRFIFTPAVSGTIVACMGLGLFPIAIK
                     NLAGGMGNETFGNPINFIVGISVSLMILGLNKYGKGLFKDASILVSIIFGYILSLILG
                     IVNFSSIQEFTLVALPKPLAFGLDIRLEVVVMFSIIYLVEIADIMGACTLSAVGGLNR
                     QVTDEELSSAVLGNGVLSTIGALFSATPMGMFGQNSAIVSNTKVVSKFVLAIGGIGLF
                     LAGISPLLANLIRTIPPCVVGGATLVIFSTLTTSGLRLVSMDGFNQENSMILGLSMAS
                     GIGFMVAPQVLEKFPKFIETLLADSSVVSGAMVAIIIQALYMVKFPGNKSDKVEDKNK
                     SL"
     gene            complement(13583..14548)
                     /locus_tag="KOU88_001467"
     CDS             complement(13583..14548)
                     /locus_tag="KOU88_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211367.1"
                     /translation="MVMQVQEKILELLYTINEDVVSIKNDMSEVKQEINVLKEDMSEV
                     KQEITVMKEDMSEVKQEINVLKGNMSEVKQEMIVMKEDMSEVRQEINIMKEDMSEVRQ
                     EINIMKEDISEVRQEMTVMKEDMSEVKQEINVLKEDMSEVRQEINIMKEDMSEVRQEM
                     TVMKEDTSEVKQEINVMKKDMSEVRQEITVMKEDVSEVKSEVNFMQNKINNINEDMNG
                     IKDEVSIANEKLYGIEIKIDSLECEDKSMKEIQIEQNNILGSLLHNSEINKATHDNIE
                     HNIAYIKGDTNSIKEDIAEIRRDLNLVELATSKNWSDIVKLKSVK"
     gene            complement(14778..15863)
                     /locus_tag="KOU88_001468"
     CDS             complement(14778..15863)
                     /locus_tag="KOU88_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBK3211368.1"
                     /translation="MYNFLGKELKSPLIIGSGPLTYSAAGCKILSDAGAGAVVTKTIR
                     KERAINPAPHMVRNTANALLNNEKWTDFEPEQWIDFEIPQMKRDGTVCIASIGHTIEE
                     SSELVEKVANAGADFIELVSYDYRDLIPMLKDAKERVNIPVIVKLPPMIDEIGDFAKK
                     LEEAGADAITACDSVGPAFRIDIETGQPLLGGNGIGYLSGETIKPITLQRIYEIKKQV
                     NIPIIGLGGCVSGDDALEMIMAGADFVGICSVVILKGAQVISKIHDDLKSNLNRLGYN
                     TIENACGIVHNHMGDVNERLSFEFTYDEEKCTKCKMCERVCAYQARKLNDKMELNEEE
                     CRYCGLCISVCKPKALGRKISCSELNV"
     gene            complement(15899..17212)
                     /locus_tag="KOU88_001469"
     CDS             complement(15899..17212)
                     /locus_tag="KOU88_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBK3211369.1"
                     /translation="MIAIKSKYLISSADEIYTNSAVVVENDIIKDILPNEEVEIKYKN
                     IEEIIDKSDAIIMPGFVNGHMHQYGVLSRGIPANVHFTDFEGFLNDYWWPFIENRIGL
                     KEVKATTKASAIELIESGVVAFCDTLEAPNTEEGTLIEQGKILEEIGMKAILSLESCE
                     RISFENGLRCLDENSNLIKWSRENSKLINGIMCTHTSFTCSDRFIKKAKEDAKKLNAP
                     MQFHLCESIYEPNYAEKHFGKKAVDYYNDLDILDETVLASQCVKVNDEEIDILKEKGV
                     KVVHMPLSNCEVGGGFSPVPKMIKKGIKVALGTDGYINDFFEVMRGAFLMHKSVEEDA
                     SVMPANLVFRMATEHGAYVLGLQNSGKIAVGNKADIIVMEDEFKTPVTLDNIFDQIVV
                     QGKKEFISNVYIDGRHILKEKQLVDLDKKAIVKEMKEVACEFWKF"
     gene            complement(17213..19504)
                     /locus_tag="KOU88_001470"
     CDS             complement(17213..19504)
                     /locus_tag="KOU88_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBK3211370.1"
                     /translation="MVNKEVRKIDSEAIVTGKPIYTEDLIFHKDVLTIKLLRSPHAFA
                     KIKNIDIKNALKVKGVVNIFTYKDVPNYRYSMVGESYPEASPHDQLILEDVVRYVGDE
                     VAIIAAEDERAAIKAMKLIKVEYEVMTPILDARESEGNKILIHEEDDLFCPFDFGLDA
                     TKNIVSREKMGKGDVEKEFKESDVIVEHSYMTQSQAHCMMETHRAYTYIDTNGRLVVT
                     SANQSAYHMRRQVSKALGIPLSKVRVIKPRIGGGFGGKNIAVTEIYASFVTWMTKRPA
                     KLIYTREETFAMTNTRHQMFFDIKIGADKEGNIKAIDMKALNNTGAYGDNGPSVCSES
                     GHNVLPTYNNVPAIKFDGRTVYTNLVPGGALRGYGATQGTFALDCAIDELAHKLNMDP
                     TEIKLKNIIKKQTEGGIMNFPIRSCALDECIIRGKKLIGWDEKYPVRDIGNNKVRAVG
                     MSVGTHGSGIANIDMAIVNMRMDEDGTYKLFSGSSDLGTGSDTILAQIAAKALNTSID
                     RISVYTGDTDMCPYDTGAYASCTTYVTGNATIKSAESLKQKILKVAQKKLDLPIDDLI
                     LYEDRVCYSEDVEKFVLLSELGKESVGGGNQEVLYSSESYGIQESAKPFLAGFAEIEL
                     DKTTGEFKVINYACSTDCGTVMNPALARIQVEGGVTQGIGLAMYEDPRHGSDGKLQTS
                     NLLQYKVPTKKDIGNIIVDFVDNYEPTGPYGAKSLGEIVIHTPAPAIANAIYNATGVR
                     IRELPITSEKVYMAMKKLNQGGK"
     gene            complement(19494..20288)
                     /locus_tag="KOU88_001471"
     CDS             complement(19494..20288)
                     /locus_tag="KOU88_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBK3211371.1"
                     /translation="MITIKEYVVPKSLDEAYELLISRKNNIILGGCGFLKLGSKNIGS
                     AIDLKDLALDYINETDDSILIGADTSLRTLELNKVIKNYCNGVISNAVSNIVGVQFRS
                     GARVGASVFAKYGFSDLIPSLLVVDAKVKLYKKGVMNLADFLESELEKDILIEVILPK
                     KDAIGVFDSIRKCTGDFAVLNGAMLKEGSIYKIAIGARPRRAKIAYKASEILSLENDI
                     EKAGEVSSEELSFGSNIRGSKEYRKDMAKALVVRMYNSIGGECDGK"
     gene            complement(20327..20773)
                     /locus_tag="KOU88_001472"
     CDS             complement(20327..20773)
                     /locus_tag="KOU88_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBK3211372.1"
                     /translation="MIIKCTINNKEKELSIRPDDFLADTLRENGYVSVKKGCDTGSCG
                     LCTVMVNDKAVLSCNYLTARVDGQHITTLEGVLDEAKKFGDFLADEGADQCGFCAPGF
                     IMMVLAMKRELQNPTEEEVIDYVNGNLCRCTGYKGQLRAIHKYLNT"
     gene            complement(20845..22251)
                     /locus_tag="KOU88_001473"
     CDS             complement(20845..22251)
                     /locus_tag="KOU88_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3211373.1"
                     /translation="MMDILIKNAIIVTVNKEREVIFDGALVVKDNKIADIGNSKEIES
                     KYTDVKKIIDAKGKVLFPGFINTHNHLFQTLLKGLGDDMVLKDWLETMTFPAANYLEP
                     KDTYDAAMLGCIEGLRSGITTMVDYMYPHSKPGLCDGIIDAYKELGIRGILGRGCMNT
                     GAQFGVHPGIMQDVETVEKDVRRLFEKHHNTENGRIKIGVAPAAIWSNSQEMLEMLWR
                     VVKEYDDALFTVHISETPFDREAAKELHGQYDIDVLEKLGILGPNVLMVHCVYLTEKD
                     MELTKKYDMKVSHNTASNMYLSSGVAPVPEMLKKGITVSLGVDGAASNNSQDMLELMK
                     LTALQHKVNKCDPLAMSAEKVLELATIDGARAIGMEDEIGSLEIGKKADLLIFNPMLS
                     PKAIPMHNPVSTLVYSSSMKNIESVIVDGNIIMEDSKILTANEEKALKDAQDTAERLC
                     VRGTIKNRMEGHKWNSLY"
     gene            complement(22269..23639)
                     /gene="hydA"
                     /locus_tag="KOU88_001474"
     CDS             complement(22269..23639)
                     /gene="hydA"
                     /locus_tag="KOU88_001474"
                     /EC_number="3.5.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropyrimidinase"
                     /protein_id="HBK3211374.1"
                     /translation="MGTILRGGTIITSDKTYISDLRIEDEKIVEIGNNLEINGDKVID
                     ATGKIVIPGGIDTHTHFDMNAGSITTADNFETGTRAAIAGGTTTILDFAEANEGENLL
                     QGVEAYHKKASGNCYCDYGFHMTITCLNKDTFNHMEKLISDGIVSFKMYMAYDGMKVD
                     DGTIYRVLKKARDLGCIVGFHCENGDLLDVLIEENIQNGNLEPKYHPLTRPNIVEKES
                     VSRLADITKLSNSKSYVVHLSCRESLETVKMAREKNIDMIVETCPQYLLLEDNLYNKD
                     KFEGAKYVMSPPLRKKEDINYLWEGLSSGDIQTVGTDHCSFNFKGQKDLGIDDFSKIP
                     NGAPGVEHRLALLYTYGVLENRISVNKFVEVTSTNAAKIFGMYPKKGEIAVGSDADIV
                     ILNINKEETISYKTQKQNVDYTPYEGFKVKCKVEDVFLRGNHVVQSCNVKEHPTGQYI
                     KRKITK"
     gene            complement(23772..24959)
                     /locus_tag="KOU88_001475"
     CDS             complement(23772..24959)
                     /locus_tag="KOU88_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBK3211375.1"
                     /translation="MLNEQRKQEVTEICQKLIQNPSSSGNEEGVVKAIEESFEKLGFD
                     SWSRDRYGNIVGCIKGNKPGKKILFDGHIDTVPVPDASKWSVPPFEGKIVDGKIYGRG
                     TSDMKGQYTAMMSAVAYFAKDTNRDFAGELYVAGVVHEEIFEGVSAREISKAVQPDYV
                     VIGESSELNLKIGQRGRGEIVVETFGKPAHSANPEKGVNAVYKMASVIQKIQQLVPPT
                     HPVLGDGILVLTDIKSSPYPGASVVPDYCKATFDRRLLVGETREGVLAPIQALLDEMM
                     KEDPELNAKVSYAVEKADCYTGNTIESERFFPGWLYDEEDEFVQAAYKGLKEAGIDSE
                     ITQYSFCTNGSHYAGEAGIKTIGFGPSKENLAHTIDEYIEQEQLFVGTEGYYGILKSV
                     YGK"
     gene            complement(25086..26300)
                     /gene="dpaL"
                     /locus_tag="KOU88_001476"
     CDS             complement(25086..26300)
                     /gene="dpaL"
                     /locus_tag="KOU88_001476"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBK3211376.1"
                     /translation="MLKEIKWKVNNLPKGDKENCIKFLNEEEITKVRNFHKSFPQYKE
                     TPLANLEGLAKKLGVAGVYVKDESYRFGLNAFKVLGGSYSMGRYLAQRLDTDISELGY
                     DKLTSKEIKEKLGEITFFTATDGNHGRGVAWTANKLGQKSVVLMPKGSSEFRLNKIKG
                     EGADASITDLNYDDAVRLANDYAEADDHGVMVQDTAWDGYEEIPAWIMQGYGTMAQEA
                     IEQLKEYGVDRPTHVFVQAGVGSLAGAVQGYVASIYDECPITVVVEADEADCYYKSAE
                     AGDGKPRFVGGDMPTIMAGLACGEPNTIGFEVLKNHAAAFVSAPDWVSAKGMRTLGNP
                     LNGDEKVISGESGAVTTGLLVAAMEREDLADLRKDLKLDENSRILLISTEGDTDPDKY
                     RSIVWDGEYPSI"
     gene            complement(26663..27334)
                     /locus_tag="KOU88_001477"
     CDS             complement(26663..27334)
                     /locus_tag="KOU88_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3211377.1"
                     /translation="MAKILGICGSPRKGATEYAVLEALKEAETIPGIETEYWSVRGKK
                     ISPCVHCDACIRKETMCIIKDDIQELEQKILEADGIIVGSPVYDMNITAQLTAVFNRL
                     RPMYLVHPGKLQNKVGAAITTGGTRYGGQELTKLPIINFFLMHEMLVSGGLGGCYIGG
                     TIWSKDGKAKGAQEDETGMDTVKRLGKGAAEAVMVSKFGLEKWNVVKEELDVKKDEKS
                     PLRDH"
     gene            complement(27417..29633)
                     /locus_tag="KOU88_001478"
     CDS             complement(27417..29633)
                     /locus_tag="KOU88_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBK3211378.1"
                     /translation="MEKVIGKSYPLKDAALKVTGQMKYVADMKPQNVLYAKMLLSPVA
                     HAKIKSLDTSEAEKVVGVRAIATYLNTSQRKYNGSLRFYEHKIPENEVIFSDTVRFVG
                     DRVAAVAAETPEIAEKAVKLIKVEYEELPAVFTIQDAIKEDAICIHGDSNIVSQNNIN
                     GGDVEKGFKECDYIFEDEYSTPAIHHSAIETHSVIAHYDYNDKLTVHTPCQNTFGFRI
                     ILSQIFGMSLNKVRVIRPAIGGSFGGKLELTIEPVAAALSKMTRRPVKMVLTRKESMI
                     STRTRHGSFVKLKTGVNKDGEVIAQDIKIYTNTGAYASSALNVIGALSHKVFKVYKIP
                     NIKFTGMPVYTNTPIAGAMRGYGSPQIFMAQQAQFAKIAKEIGMDLVDFQNKNAVEPD
                     DVDIIFHGSLGNPRVLDCIEQGKKIFKWDEKKKLPKEEGKYLRGIGMAIGAHGNGVFG
                     AHRDVVTLTLKLNEDGTLTLLTGAHDMGNGVVTMQTMMVAEVLGITPDKVDTFETDTD
                     ACTFNLGDYASRGVFVEGGGAKKTAEKLKNLILEEAEKLLETSKEDLYLDNGYVISKL
                     DENVKASLSDVAVYSQSKSLRELTVVEDYSSPAGRTSYGVHFAEVLVDKETKDIKVVD
                     FVAVHDVGRVINPLNLEGQLEGGIHMGLGYALSEELAFDEQGRPKATDFKTYKLFRTV
                     DMPKCQVAFVDGYEKAGPFGGKSIGECAVVPVAPAVANAVYNATDVEIHSLPIKLK"
     gene            complement(29636..30106)
                     /locus_tag="KOU88_001479"
     CDS             complement(29636..30106)
                     /locus_tag="KOU88_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="HBK3211379.1"
                     /translation="MEKIKLNINDYMYEIEVEKNETLLHVLREKLNLTGAKQGCNSGS
                     CGACKVLIDGVDMKSCKLLAKNCEGKVIYTIESFANGENLHPIQEAFIEVGAVQCGYC
                     TPGMIITTQALLNRNASPNEDEIREAFKENLCRCTGYVKIIEAVKLSAARLGGR"
     gene            complement(30168..31562)
                     /locus_tag="KOU88_001480"
     CDS             complement(30168..31562)
                     /locus_tag="KOU88_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3211380.1"
                     /translation="MIDILIKNAIIVTVNKDRDVIFDGAIAIQGDRILDIGNTVDIEP
                     KYLDAKKVIDANGKVIFPGFINTHNHLFQVLLKGLGDDMALHEWLNTMMFPSAKFLTE
                     QDTYDAAMLGCMEGLKSGITTMVDYMHTHNRPGLTDGIVKAYKDLGIRGVVGRGCIDL
                     GIHKELIEDVETVEKDLRRVFEKYHNSENGRIKICVAPSSMWAISEEMGKMLWNIVKE
                     YDSYFTVHISETEFARTATKDIHGEIDIKLLEKWGIVGPEVVAVHCVCITDEDMEMLK
                     KYDIKVSHNVASNMYLASGVAPVPEMLKKGINVSLGLDGAASNNAQDMVELMKLTALQ
                     HKVNNCDPLAISAEKVLEMATIEGARTLRMEDEIGSLEIGKKADLVIFNSMLSPKSIP
                     LHNPVSTLVYSASMHNVESVLVDGNVILENGKVTTIESEEQVLLNAQHAAEELCKRAN
                     VTNRMEGHKWNSLY"
     gene            complement(31635..32996)
                     /locus_tag="KOU88_001481"
     CDS             complement(31635..32996)
                     /locus_tag="KOU88_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine/pyrimidine permease"
                     /protein_id="HBK3211381.1"
                     /translation="MKTRNTSKYDVDGIPPLKESIPLALQHLLAMIVGNMVPAILIAN
                     VVGLNQGQATMLIQGSMLAAGLATFLQLYPIPLFKGFKLGSRLPVMMGMSYVFLGACL
                     SVAAKDGLAALFGAQIAAGVIVFFVGFGVKKIRHIFTPIVSGTIIACMGLGLFATAIK
                     NLAGGEGTQTFGSPINFTVGVIVAFVIIMINKYGKGLVKNSSILIGILVGYAISLVLG
                     LVDFSAVQGAAIVSLPTPAAFGLEFRPELIVMFTIIYIIGIADMMGACTIATVGAMDR
                     EVTDEELASVVLGNSITSIISSLFAALPTGVFSQNTVIVSMNKVTSRFVIALGALVLL
                     LAGISPALGAIMTTIPSCVVGGATLVVFSSIAMSGFSIMSMDGFTEENNLIAGVSIAT
                     SMGLTTAPQVLDQFPETIGTVLGGSSIVSGAIIAILLQTLFKLKSRKSAENVTSNLEE
                     NIG"
     gene            complement(33293..34615)
                     /locus_tag="KOU88_001482"
     CDS             complement(33293..34615)
                     /locus_tag="KOU88_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBK3211382.1"
                     /translation="MFDIDGRPPILKCLPLSMQHILAMIVGTVTVPIVVGGAVGVSPT
                     QITLLVQYALIIAGISTLIQLYPIGNIGSRLPIIFGVGFTYVPTLVAVGGNYGLASIL
                     GAQLIGGVATVLIGIFIKKIRKFFPNIVAGTVVFTIGLSLYPIAINYMAGGVNSPTYA
                     SMQNWAVAAITLVVVIGLSQFAKGYAKLAAIFLGIIVGYCVSLVLGIINFDPIREATW
                     FAIPKPLEFGMEFDMPVIISVVIVSIINAVQAIGDLSATTMGGMDRNITDKELSSGVI
                     GSGICTMIGALFGGLPPSSYSQNVGMVAMNKVISRFVLGIAGIFMLLSGFVPKFGALM
                     TTIPYSVLGGATISIFSMITMTGIKLIITEELSSRNITIVGLAIALGMGITSVPAAQE
                     AFPSFVKLVFGESPIVIATLVAFVLNLIIPNKSLEDEAKERAVMEETN"
     gene            complement(34971..36011)
                     /locus_tag="KOU88_001483"
     CDS             complement(34971..36011)
                     /locus_tag="KOU88_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3211383.1"
                     /translation="MDKHSDSVMYGGMEVYNIWGTTTVDSIIGESDVMRALKNRICKI
                     GNSDSTVAITGESGTGKELIARAIHLAGNRGNKTFVAINCAAIPEPLLESELFGYTKG
                     AFSGADSKGKIGKFELANGGVVFLDEIGDMPIQLQSKLLRVLQEKKFTRIGSNELIDI
                     DVRIISATNRDLFELVKENKFREDLYYRLNVIPLEVPPLRERGDDIQILINNFIDKYS
                     RKMKKNVYHIEPDVEQMLLKYPWPGNIRELENTIELALNLLEEDGIIHKGIINRKILE
                     YFKLNNINIKLLEESDYEISMEQDILTLEEFERAYIKKVLKFYGNDTKSKKLAAKKLG
                     ISLATLYRKIDV"
     gene            complement(36338..37606)
                     /locus_tag="KOU88_001484"
     CDS             complement(36338..37606)
                     /locus_tag="KOU88_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HBK3211384.1"
                     /translation="MSKNIYVKETYEWIRVGNGENELTEIEYEKLLKHLENNNDVLKS
                     NIIDIKYKKLRFINYVGIICFENVILEILPKLSLSDNLVKDREILLQMLSICNKIPIT
                     MNEKIRLSLKNYNLLNFFVMYFIESMQTQMKKGIYFEYINKIENLNVMRGKILLSTYA
                     KEKGISPMKIRCEYDEYSENNFLNQVLKKACISILCRINDNSIQGKIKKILSYFQNVD
                     LIYIDRKKLLDYKFYKNNDRFKDCYLLARLLLLNLSMDNSQNNQEAFSILFEINTLYE
                     EYIGILIKSIWDNSFRETYIQDKSKFLLKNEQTGKKNFNLRPDIVLYDLKNEYEIIID
                     TKWKAIEVDSNVFYRSSDIYQMYAYITAYENAKRCILLYPCIQKDKNYSSWKLSESFK
                     GKFIEAKTVRLDDIKNTKNDLKKIIFNYKF"
     gene            complement(37599..39533)
                     /locus_tag="KOU88_001485"
     CDS             complement(37599..39533)
                     /locus_tag="KOU88_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3211385.1"
                     /translation="MSENIRGTEYWLMEEFFYQETDTPQIFREESIIALGFDIKINLK
                     KVFSMGKKSEKYINENCNDKDFIKKFMLIKKGDYFLYKAYQNIEEKVKCNVSIGIVEE
                     DFENGYELSHILGHTLPVKWMHNFDTVSNCKVYTSEFYKLNNNDISSYLEIIKSQDKK
                     LLRKRIEESENNKWYLKNYYYKNVDKCVDDEELFIQPINLEQLESLKNIKTDDYILLY
                     NSEKVICENDHTMKSLFGVCQVMEGFDKEKVSALEGGYFFPVRWIEYEKENIDGNAWV
                     IFENNSIVEKYVKRFTNKMPLNTILYGPPGTGKTYNTKQMVYNLVSETSLRNRYYTGY
                     LDYKNNVEFCTFHQSYGYEEFIEGLKSDGEGNFKPEDGILKDISIEACYNALKFEKKM
                     SFELEKDSLTLETIKDRKKKLVLENIEYSESFNFEESENYVLIIDEINRGNVSKIFGE
                     LITLLEDDKRLTKSNQTIVKLPYSKEKFSLPPNLYIVGTMNTSDKSIALLDIALRRRF
                     NFEEIMPDYDLLSIVDGIDIRKMLYTINKRIEFLYDRDHVIGQAYLLAVENINDIVVV
                     FRSKIIPLLQEYFYYDSEKVGLILGGIGRNEKDKYIVYKEKLIASELFKNNNASIMES
                     KVNYCIKQNISSEELKNIYE"
     gene            complement(39562..40284)
                     /locus_tag="KOU88_001486"
     CDS             complement(39562..40284)
                     /locus_tag="KOU88_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein"
                     /protein_id="HBK3211386.1"
                     /translation="MENFNKNAKIIGIGAEGINIINEVEEKIKANMDIEKININQEIE
                     KEYVRSLLDGVDILFLIYSSEDKHIRDIIKAVSYMSNERRVLSIGMDCSEKENKEDLE
                     LGREFKINNDSIFKFVDLMNIMVESISDSCMINIDITDLKEAIVGDKGIKYSFEEFED
                     TKSYSEIADILFDRMEYIGEEFISKKGIVFVEGSPEFSIMELNDLISNIQSKVEESYE
                     VIFSLYIKENLNGNIRVGLLYN"
     gene            complement(40334..41320)
                     /locus_tag="KOU88_001487"
     CDS             complement(40334..41320)
                     /locus_tag="KOU88_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBK3211387.1"
                     /translation="MSKVKRLTDVWIYINDKQKFTIKELSEEFNLSAKTIQRYLKELN
                     KMGLPIQAEQGRNGGYRVLNNSYIPPVIFTEKEVMIILFALKSLQIYNYKLMEIEINS
                     IMRKVSYERKSSIKVGIENIKRYIGFVANDTNDGDFKSSNVTEFFRASSESLILNIKY
                     KCGNQILEKNVCPIGIYLNKGAWFSPAYDCKSDKIILVHIDNIIDIKRTGESKKIHIN
                     LEEWLHEVYNNLYGNSSTTKKFGEIIYLNVLLTKEGVSKIKDSSWNLDMELNEDGSGI
                     ISTFIKVEDIDCYASILFFIGNNAKVIEPKFLNKLLYDKANELRYFYEENMV"
     gene            complement(41377..41877)
                     /locus_tag="KOU88_001488"
     CDS             complement(41377..41877)
                     /locus_tag="KOU88_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBK3211388.1"
                     /translation="MRKNSINIALTAAITAIYAVLTLSLGFISYGPIQFRVAEIMMLL
                     AFLDKGYIVGLTLGCFLANVIGPYGVPDIIFGTLATFISASMIYITRKLGKQNKSTLV
                     IASLWPTVINSIVVGLMLNVFFGLPLILSMIQVGFGEFVVVTIVGVPFFCFLMKKYKN
                     VINIKF"
     gene            complement(42163..42474)
                     /locus_tag="KOU88_001489"
     CDS             complement(42163..42474)
                     /locus_tag="KOU88_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211389.1"
                     /translation="MAGNLNNMRAVNNFRGDKSILECLVSFEGRSISQRKVRVFFKEK
                     QNQIEIDFAEEEISKLVENVVLSTSYQEMLYDEIEKQLEIDCIGTWMILSKLKDGSRV
                     H"
     gene            complement(42614..44878)
                     /locus_tag="KOU88_001490"
     CDS             complement(42614..44878)
                     /locus_tag="KOU88_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBK3211390.1"
                     /translation="MNIVGKGIKKIDGMSITTGKPVYTDDLSAKDALVVKILRSPHAY
                     AKIKDIDTSKAEMVDGVECVLTYKDVPKSRFTLAGQTYPEPSPYDRLILEDVVRYVGD
                     EVAIVAAIDEKTAIKAMNLIKVKYEVLTPVLDFEEAIGNKTMVHDEDRHCNFDIGMQR
                     EKNIVSHHDYTKGDVEKVLSNCDVVIEETYYTQAQAHAMMETYRAYNYLDHMGRLVVV
                     SSTQIPFHVKRHLSRALEIPASKIRVIKPRIGGGFGGKQTACVEIFSAIVTLKTGKPA
                     KIIYDRKETFNCSTSRHAMRLKVRLGATNDGIIKAIDIKALSDTGAYGEHASTTIGLV
                     GEKTLPMYNKVEATRFIADVVYTNKMPAGALRGYGASQGCFAVESTINMLANKLKMDP
                     TDLRLKNVVTEGETTFAYGKTLNSVDLIKCINKGKELIGWNEKYPCKHLDNGKIRSVG
                     MAITMQGSGIQGLDKSSAEIKLNDCGDYTLMIGSTDMGTGSDTILAQMAAEVLDTSIE
                     NITVISADTDLVPYDPGSYASSTTYVTGMAVVKAAQDLREKIISAGATKLGVEKDEVE
                     FDGIKLTSKKGSTLLFDIAVDSTIGPDTNQLIGLASHGSPVSPPPFIAGFAETEIDTE
                     TGKVDLVNYVAVVDCGTVINKNLAKIQVEGGIVQGIGMALFEEVRYTEKGSMDTNTFM
                     QYKIPARCDIGNVKVDFVETYEPTGPFGAKSVGEVVINTPLPAIQEAVFNGIGVRINT
                     LPITPEKVFMEMNK"
     gene            complement(44882..45331)
                     /locus_tag="KOU88_001491"
     CDS             complement(44882..45331)
                     /locus_tag="KOU88_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2Fe-2S iron-sulfur cluster binding
                     domain-containing protein"
                     /protein_id="HBK3211391.1"
                     /translation="MLVKININGKKKSVDIEPEEYLVDTLRKVGNLSVKRGCDTGCCG
                     LCTVLIDKKPTLSCATLTLRALDKEITTIEGLENEVKEFSEVLVKEGAEQCGFCSPGF
                     ILTVLAMKDELENPTDDEIKHYLTGNLCRCTGYMGQLRAIKTYLEVK"
     gene            complement(45331..46119)
                     /locus_tag="KOU88_001492"
     CDS             complement(45331..46119)
                     /locus_tag="KOU88_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD binding domain-containing protein"
                     /protein_id="HBK3211392.1"
                     /translation="MFTVMDIVQPDTVEEAYSILNKRKTNQVIGGSAFLRMGKKRIGT
                     GIELSKLNLDYIKEYEDYVEIGSMTTFRTLETSSIIKNNFGRIIEDSVKNIIGVQFRN
                     VVTVGATVFSKYGFSDLIVALLSLDTEVELYNIGRISLEEFLNRDYEKDLLIKIYIKK
                     TNKNASYKSIRNAKSDYPILNVSVSKHMEQFKLCVGARPQKATIAKQASEFLSNNEIN
                     EINIDKAVEIASEELTFGSNMRASREYRKAMSKVLLKRAIMEVI"
     gene            complement(46314..47582)
                     /locus_tag="KOU88_001493"
     CDS             complement(46314..47582)
                     /locus_tag="KOU88_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBK3211393.1"
                     /translation="MEASIHTIASNNLLIIFAIVSITGIICSKLSEIIKVPDVVLYLL
                     VGILIGPSFLKFIDIRGFQIENQLILTFGSAFILYLGGKEISLKVLRNVKISVFLLAT
                     LGVVISAFIMQQVIGFTFGISAMTALLAGTIIASTDPATLVPIFNQVKIKDRVKQTVI
                     SESAFNDATGAILTSAVLAVILSNKFSLGENIYELGTMVIVGVLVGLITGILLLKLVN
                     DKPYGIFKDFAPIISVISVVVAYELSTKLGGSGYMSCFIVGIITGNKKNFKIWLSQKS
                     YDADFYVAETLGTICRMAIFIILGSQVNLAQLSKYFMPSVITVLVLMFIARPLCVLVC
                     TLVDREAKWSKSEILFMMWVRETGVIPAALCGIISAMKVPGYEVISSVVFMTILITLV
                     IQGSTTKLVAKKLGLLEEEVINISEKVSTF"
     gene            complement(47923..48084)
                     /locus_tag="KOU88_001494"
     CDS             complement(47923..48084)
                     /locus_tag="KOU88_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III"
                     /protein_id="HBK3211394.1"
                     /translation="MKQDKKNEKQSEISKIKQSNDNKLEIAQELHVSKNIGNMLGDRI
                     DKKKMNRPS"
     gene            complement(48233..49315)
                     /locus_tag="KOU88_001495"
     CDS             complement(48233..49315)
                     /locus_tag="KOU88_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBK3211395.1"
                     /translation="MRKLSKREKDFIQYGFLLFLICITTYLVLTTLDIKLIPKIIRLV
                     NKTYIFLGILTIIVYMIIESIVTHLIINAVQKTKVKFIGIKMATMGFYYNLVTPFASG
                     SQPMQIYALTKYDVSLSKSVAIVTNKTVVFQSTVTVFCGILILLNKSLLMEQVHSVKV
                     LITFGMIMNVSMLLGGLLIVFSPKQVKMIAEVLINFLSKFKTFKFLDSKRDRINHYID
                     DYNYSIKIFIKNVRILVLSILLTVLQLIAYFSIVYCVYKASNLRGVSYVHIMTLQVFL
                     YMAISPIPTPGNVGANEVTFFTMFSNIIPKELLGYSVLLYSGFVYYFILIVSGLFTFG
                     THYTLNSWKKEDKVNSNLDKVIEKLN"
     gene            complement(49418..51013)
                     /locus_tag="KOU88_001496"
     CDS             complement(49418..51013)
                     /locus_tag="KOU88_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211396.1"
                     /translation="MSNLSILIKTNIINEFKLNALKKADGREKQKIMGMMLSVVIIAG
                     LLIFYVTSLSLSLVDILKQINQLEMLLIFGFGLSTLTTIVTSLYKTSSYLFQAKDLDL
                     LTSLPIKESTVLASKILMLVGANYLFSSICMIIPAVVYFLNSDVSITYFPYLILLFLA
                     LPLLPIVASSIIFLFIGQISSRIKYKNLVLIIGSIILMLLYTLLMSRLNSMSVEMLKN
                     SVSISETIRKVYPPIYYFVDALKTGSIVSFLAFIAISIIPFFMFVTLFAKKFKDINAK
                     MSEGYKSKNYEFKGQKTSRPSKALLKKEFKRYTSSFIYFLNSSAGLLFLIVGTILILL
                     FGADKVGELLKLNIDFNLIKIQLLGVFFFIIVMNCTTYCSISLEGKNLWILKSSPIDE
                     REIFWSKILMNFLLNAPLSILCLILVSIRLDFEIQFIIVSICLIGSFSMFVALMGLLS
                     NLLYPNLDWKNEVAVVKRSASMIVTMLVSLAYVIILGGIYVLLGISFLNIYIILASIL
                     TLILDFMIWRIISTKGVKIFKNL"
     gene            complement(51060..51767)
                     /locus_tag="KOU88_001497"
     CDS             complement(51060..51767)
                     /locus_tag="KOU88_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211397.1"
                     /translation="MLKVINVSKSYKNKKVVSSVSFDVNDGELFGFIGHNGAGKTTTI
                     KAIVGIHDFEEGEVLINSKSIKKQPVECKKEMAYIPDNPDLYESLTGIQYLNFIADIF
                     EVAKDKREELIKYYSNKFELNKALGDLISSYSHGMKQKLAIISALIHSPKILILDEPF
                     VGLDPKASFILKEIMREFCDKGGCIFFSTHVLEVAEKICDKIAIIKDGNIIAYGTTEE
                     VKGSNSLESIFMELIEK"
     gene            52020..53165
                     /locus_tag="KOU88_001498"
     CDS             52020..53165
                     /locus_tag="KOU88_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK3211398.1"
                     /translation="MNTFEQLKISSTLIDGLKKQDINSPTEVQSLVIGNIIQNKDLLI
                     NSQTGTGKTLAYLLPIFEKIDTSKRETQALILAPTHELVMQITNQVELLAKNAELSVT
                     SLALIGEVNIQKQIKNIKAVKPHIVIGSCGRVLDLIKQKKLKSHNIKTIVLDEVDNLL
                     NGKNITCIEDIIRTTLRDRQIIGCSASLTDSTIKICDKLMKEFEIIKTKEKSQINPNI
                     NHSYLLGEIRDKFTFLRKALAATNPKKAIVFVNNEKNIEVLVSKLNYHNYKAIGIFGN
                     MEKEDRKNAINKFKLGKAKILITTDLSARGLDIVDVSHVFNLDFPKSKNEYLHRCGRT
                     ARGNRSGNTISIITKKELDIIKDLQKEFNIVITPKTLQNGELIDIIK"
     gene            complement(53262..54638)
                     /locus_tag="KOU88_001499"
     CDS             complement(53262..54638)
                     /locus_tag="KOU88_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBK3211399.1"
                     /translation="MQTTNSSTMQKLFPILTNKNVDMKKEIIAGVTTFLTMAYIIAVN
                     PNILSETGMPAGALVTGTCLAAAFGCILMGVVANLPFALASGMGLNAFFAYTVVLQMG
                     VPWEVALTAVFVEGIIFIVLSVSGVREAVVNAIPKNMKLAVTGGIGIFIALIGLVNSG
                     IVIGDQATLIKMGRFTPAVIITCVGLIIIAVLDKKRVKGSILFGIVVSSLLAWAFAFI
                     NPEYAQKLGIYLPGGLFKFESLAPIAGKIDLGYVLHPTNIGGFLVVVCTFLFVDFFDT
                     VGTLVGVCSKANMLDEKGNVPNVGRALLTDAVATTVGAGLGVSTVTTYVESSTGVIAG
                     GRTGWTAITVGILFLAAMFFSPVFIAIPSCATAPALIYVGYLMLGTVKDIEFDNITEG
                     VPAFVTIACMALTYSIGDGLTLGILTYVFVNIFYNIFGAKKAEDKKHVSVVMIVLAIL
                     FIIKLWLL"
     regulatory      complement(54732..54834)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            55084..56430
                     /locus_tag="KOU88_001500"
     CDS             55084..56430
                     /locus_tag="KOU88_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3211400.1"
                     /translation="MKDLTTGHEGKSIFFFAMPMLIGSLFQQLYNTADSIIVGRFIGK
                     EAMAAVSGANPIMFLLVAALMGVSLGFSILVSQFYGSGDLKKVKATIDTTYILLFIGS
                     ILISILGIVFGGPMLKLMNTPESVFAQSKLYLTIIFSGILFSAGYNSVSAILRGLGDS
                     VTPLYFLIIATILNIVLDLTFIVVLRMGVEGVALATIMAQAVSFIISIIYLNKKHEVL
                     KFKIKGIVYDNKIFKDGLRLGLPSGVQQMLFSIGNMALQFLVNSYGTSAMAAFGAGLR
                     IENFISLPIMNLGSAVSTFVAQNIGAGENERVKKGIRESIKMTLVLAVTVIALILLFR
                     ENLIALFNTDKDVIKIGSSYLFIIGPFFLFIGTSFVLSSAMKGAGDSMFALISSIVSL
                     WLGRLPASYMLSKFFGTDGIWMGIPFGWTLGLIVTVIYYKKGHWKTKAIVNHRINE"
     gene            56508..57902
                     /locus_tag="KOU88_001501"
     CDS             56508..57902
                     /locus_tag="KOU88_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBK3211401.1"
                     /translation="MGIILKPKQFYMTVIATIILYFSLNYSFNIKFSICLSFLTILIW
                     AVDSVEKTFVALFFVILAFIFNIAPIKVILQFLFTENFYIIILAYIITNAVTKTGVAK
                     IISEKLILNTVNTPKKMILLSYILGILLIFFIPQPFPRVILVSAFYKEFLKEQQITED
                     SKSILLFSIFTASTFTSMFFVNGDTLLNYVVLELGNCNINWGQWAFYMSVPTIITCFI
                     TYFLFIFVFKKELHSIKFISNENLEGNKLHFSYSNLKKEFNLLNKEQKHVFLCLGIMF
                     FMFLTQFIHNINTLIIMSICVLLLLLRKIVGFSTLKEINWKVLIFFIAAFSIGGVLKY
                     SGVVDIMGNYLIKFIPNSSEIISILFLITLTIILNICLGSAVTTSSVVIPLLGSLHIL
                     KENSVTLCLFVYIIVSIQYILPFHHATIMVGHGENLYNSKVIFKYGLTLIPLTYFIII
                     CITFPWWKFIGLEI"
     gene            complement(58024..58698)
                     /gene="fsa"
                     /locus_tag="KOU88_001502"
     CDS             complement(58024..58698)
                     /gene="fsa"
                     /locus_tag="KOU88_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBK3211402.1"
                     /translation="MQLILDTGNVEEIKELCTCLPIDGVTTNPSIVSKEKKNFKQLIN
                     EIGEIIGEDMPIHAQVLSTKYEEILEEALYISSLRKNIYVKIPVTQDGLRAIKDLHRK
                     GVKITATAIFTAHQGFLAAKAGANYIAPYVNRLDNISGDGVAMVSELIKIIDTYKMDT
                     KVLAASFKNAQQVIELMQHGVHSVTVPYDICKSMMNHPLTDWSVDKFIEDWENTFGKG
                     SKTNNI"
     gene            58972..59736
                     /locus_tag="KOU88_001503"
     CDS             58972..59736
                     /locus_tag="KOU88_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK3211403.1"
                     /translation="MFAEERIQAILNILKKEGRVTVKELSSKFNVTEDCIRKDLKNIE
                     KISSIRRIYGGAVLARETLENQDTKDRKEINIPTKKIIAEKAFNLIEDRETIFLDIST
                     INILLAKLLAESNKKVTLVTNMLDILNVVTSKPNNLNIISTGGLLNLSLDGFVGTPTI
                     EFISKYKFDKTFMGSCGVDVFNSSLTTFEIEDGLTKKAIINSSKKVFIVMEDKKFKFD
                     GNFKFAHLEDISSIITEKTPTPDIVDILSEFNVNVL"
     gene            complement(60025..60246)
                     /locus_tag="KOU88_001504"
     CDS             complement(60025..60246)
                     /locus_tag="KOU88_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211404.1"
                     /translation="MDRLKRDMKNMKEDLKEGVKKTAYVMKNTAEDLKDDAQGAMVNL
                     EMKKDEMMERYEQKKFSKELEKQMKNEMK"
     gene            complement(60647..61924)
                     /locus_tag="KOU88_001505"
     CDS             complement(60647..61924)
                     /locus_tag="KOU88_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBK3211405.1"
                     /translation="MRRIFDKWEKLSIKYKLFSITTSLLIALALIIYLILYFLLPSYY
                     HEYKIESLQESLKSLVDSSIHFDTYTLEERLYYMAKDQNLAILLKDNQGKIVYGKNEV
                     VILRYSKYMINSLEDEYRTSIPIYTKDAKDGPYTLELVMPLQPIDEANEVIRKLMPYI
                     ISIAILIAIIGAYIYSIVITKPLINIIESEREQEYRRKDFVATISHELKTPITIISGQ
                     IEGMIYSVGKYKDRDTYLKKSYECTQELKDLVNEMIEVSKSEILEKDLKLVSINISEL
                     LNRLVKRQVFLIEEKHMKTILKIEENLEIKADQERITKAINNIINNAIKYSPEESELI
                     IRLYDKNKRISKKTSNQRVVLEIENTGVTIEKRYLEEIFNPFYRIEKSRSRKTGGSGL
                     GLYIVSQIFKSHGFDYSIKNKENSVVFTVEFKN"
     gene            complement(61908..62576)
                     /locus_tag="KOU88_001506"
     CDS             complement(61908..62576)
                     /locus_tag="KOU88_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3211406.1"
                     /translation="MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQ
                     GSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLTALNDEGDQLKGFDLECDDYITK
                     PFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL
                     KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTL
                     EKDI"
     gene            complement(62736..65237)
                     /locus_tag="KOU88_001507"
     CDS             complement(62736..65237)
                     /locus_tag="KOU88_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBK3211407.1"
                     /translation="MSSNKVVESYKITGMTCAACAKAVERVTKKMDGVYDQSVNIATE
                     KLKIEYDNSKVNFDDIKQVVEKAGYGIIKEESNKKIDMKIDGMTCAACAKAVERVVKK
                     LDGVESISVNIATDKANIDYDPSKVKLSQIKAAIEKAGYKPIEEVRNKVDVDEDKLRK
                     EREMKSLFVKFIVAIVFAVPLFYIAMGPMIIKPIGPWPLPEIINPMTNTFNYALIQLI
                     LVIPVMIAGYKFYINGFKSLFSLSPNMDSLVAIGTLAAFLYSLYTTLQIANGQIQGMH
                     HHQLYYESAGIIIALILLGKYLESKSKGKTSEAIKKLMGLQPKTAIVLVDGKEVETPI
                     EEVEIGDILLVKPGTKIPVDGVVIEGYTSVDESMLTGESIPVEKNVGSKVTGASINKN
                     GVIKFKAEKIGGDTALAQIIKLVEDAQGTKAPIAKLADTVSGYFVPIVIAIAVVASLL
                     WFLIGGKDIVFVLTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKGGEALES
                     AHKVNTVIFDKTGTITEGKPKVTDIVLNNNVKEEYLIKIASSAEKGSEHPLGEAIVKY
                     GEEKNIKFEKVDNFKAIPGAGIQVTINDESILLGNRKLMNDNNIKLGDLEEKSNILAS
                     QGKTPMYIAVDGNLSGIIAVADVVKESSKKAIEILHDMGIKVAMVTGDNAKTANAIAN
                     QVGIDMVLAEVLPEDKSKEVEKLQNQGKFVAMVGDGINDAPALAKADIGIAIGSGTDV
                     AIESADIVLMKSDLIDVPTAIKLSHETIKNIKQNLFWAFGYNTIGIPVAAGILYVFGG
                     PLLNPMIAAAAMSLSSVSVVSNALRLKNFKAYKRD"
     gene            complement(65521..65712)
                     /locus_tag="KOU88_001508"
     CDS             complement(65521..65712)
                     /locus_tag="KOU88_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HBK3211408.1"
                     /translation="MIRVCPNCSNVDVNKLKTLVGEENVKTGCIGQCRAFKKEAVGII
                     DNELEIKETEAEFFEACKE"
     gene            complement(65860..66102)
                     /locus_tag="KOU88_001509"
     CDS             complement(65860..66102)
                     /locus_tag="KOU88_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211409.1"
                     /translation="MLEVTKIIIKYFASESDTFVKEEVCNFEELLKWSHKFIEGKKIE
                     DVLYIKSKENYKVNVIKSLEIKELEIVRKQQIPPYM"
     gene            66314..68137
                     /gene="typA"
                     /locus_tag="KOU88_001510"
     CDS             66314..68137
                     /gene="typA"
                     /locus_tag="KOU88_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBK3211410.1"
                     /translation="MSQKHKIINIAVIAHVDAGKSTLVDAFLSQSGVFRKNEVVKDCV
                     MDSNDLEKERGITIYSKNCAINYEDYKINIVDTPGHSDFSSEVERVMKTVDTVILLVD
                     ASEGPMPQTRFVLQKSLEFGLKPILFINKIDKKDQRAEEVVNEVFDLFVDLNATDEQC
                     EFPIIYGIAKQGIAKLEMDDDSEDLSPLFKTIVNHVEAYPNYDNEPLQFQISALAYDD
                     YVGRLGIGRIYKGTLKNNTQVAICREDSVVSKGKVSKLSVYEGLKQVEVDEATSGEIV
                     VIAGIPDISIGETICDLDSPLPMEMIKIEEPTLSMNFLVNDSPFVGKSGKFVTTRHLK
                     DRLEKELEVNVGLKVEPLDTTDGYKVSGRGELHLSILLENMRREGYEVGVSKPEVLMH
                     KEDGKLMEPIERVVVNCPEVYSGTIINELNMRKGMMESMSIEGDYVKIEFLAPTRGLL
                     GYRSEFINATRGEGTLVRSFEKFEEFKGEIPSRGNGVLIAQGPGVTMGYSLNALSDRA
                     VMFVDPGVEVYEGMIIGMNSRKDDMVVNPCKNKKMSNVRASGSDDAIKLSPPRIFTLE
                     EALEFIEDDELVEITPDSIRLRKRFLNEHDRLRYNKSRQGK"
     gene            complement(68227..69135)
                     /gene="trxB"
                     /locus_tag="KOU88_001511"
     CDS             complement(68227..69135)
                     /gene="trxB"
                     /locus_tag="KOU88_001511"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBK3211411.1"
                     /translation="MVDIIVIGAGPAGLTSAIYAMRAGLSVTVFEKNIYGGQVASTSE
                     VENYPAVQKISGVEFSNNIYNQAVAQGVDIQFDEVEEINLEGKVKVVKTSSGEHKAKA
                     VILANGVERRKLGCAGEQEFTGRGVSYCATCDGAFFKDKEVAIVGGGNTALEDALFLA
                     NNCTKVYLIHRRDSFRGEEVLEKSVKARENIEILYSHGVEKIEGEKTVSKIEVKNLKT
                     EEKRTIDVSGIFIAIGLKPNNKMFENVLDLDEGGYIISDESCTTSVEGVYVAGDSRTK
                     FLRQIITAASDGAIAAVQAANYINVE"
     misc_binding    69937..70168
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            70276..71757
                     /locus_tag="KOU88_001512"
     CDS             70276..71757
                     /locus_tag="KOU88_001512"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBK3211412.1"
                     /translation="MYYSSTRGTEEKVTASQAIIKGISSDGGLYVPSEFPNVKNELIN
                     LVNLTYSQIAFFVLSKFLCDFTEDEIKNCIENAYDEKFDCSSIAPLNKVNDTYFLELY
                     HGPTLAFKDMALTIMPHLLKTSIKKDNLEKDVVILTATSGDTGKAALEGFKDIDKIKI
                     IVFFPEDGVSPVQKLQMKTQTGKNTYVVGIKGNFDDAQSGVKKIFSDKEFNQKLLDNN
                     YILSSANSINIGRLLPQVAYYFYSYMKLVSNSDINLNDKINFVVPTGNFGNILAGYYA
                     KQMGLPINKLICASNDNNVLYDFFKTGVYDKNRTLKLTTSPSMDILISSNLERLLFEI
                     SNRNTDIVNKLLSDLSDKGVYKISDDMEKNLASFYGEYSNEEEVKSTINNVFKNYNYL
                     IDTHTAVAYNCYEKYKKETSDNTKTVIVSTASPFKFSEDVLKSIDCDFKDLDDFAIID
                     RLSSISKIDIPKPIKNLKNAEILHKDIYEKDELKLAIKKFLKV"
     gene            71767..72660
                     /locus_tag="KOU88_001513"
     CDS             71767..72660
                     /locus_tag="KOU88_001513"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBK3211413.1"
                     /translation="MLEIIVPATSANIGPGFDCLGIALNIYNKFYVEEIESGLEIEGC
                     EDAYKNENNLVYTSMKYFFDRVKPEKIPAGIKIKIQSEVPICRGLGSSASCIVAGVIA
                     ANALSGANLDKNQLLNIASEIEGHPDNVAPAILGNMIVSVTDNENIHYDIIKIPEELK
                     FCAMIPNFKLSTEKARGVLPKEIPYSDGVFNVSRVALLISALLNKNFDLLKVACQDKL
                     HQDYRGTLIENYNDIVEKSEQLNSIGVFLSGAGPTIMSLIKENDDSFVDNMKNYLQKL
                     KSDWEIKELCCDSNGAVLNII"
     gene            72784..73845
                     /locus_tag="KOU88_001514"
     CDS             72784..73845
                     /locus_tag="KOU88_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015617764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HBK3211414.1"
                     /translation="MIIKELIIRDLVAKVPIIQGGMGVGISRSSLAGAVAKLGGVGVI
                     SGVQIGYDEEDFETNTINANLRAIKKHISKAKEISNGGIIGINFMVAMKEYETYVKEA
                     VKAGVDLIISGAGLPNKLPSLVKGSNVKIAPIVSTAKAANVILKMWDRKEKTTADLIV
                     VEGPKAGGHLGYSNEELDNIDSIDYDKEFVEILKVANTYGEKFGRNIPVVAAGGITSS
                     SDVKKYIDMGASGVQVGTRFVATYECDAHENFKMAYINASEEDVHIVKSPVGLPGRAI
                     RNKFIEEVKINRPEIKKCYNCLIPCNPKETPYCISQALINAVKGDVENSLLFCGNDAY
                     KIDKLSTVEDVINELISEL"
     gene            complement(74000..74512)
                     /locus_tag="KOU88_001515"
     CDS             complement(74000..74512)
                     /locus_tag="KOU88_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBK3211415.1"
                     /translation="MSDFKEILAEEIKNNPFGLIGKDWTLITAENEGKVNTMTASWGG
                     LGVMWGKDVAFVVIRPQRYTKEFIDNTDKFSLTFFDEDFRKELSYCGKVSGREEDKIS
                     QIGFNIEHLNDTPYFKESKMAIICKKMYSQKLEPQCFIAEGIDGRWYPQKDYHTLYIA
                     EITNVLVKED"
     gene            75032..75967
                     /locus_tag="KOU88_001516"
     CDS             75032..75967
                     /locus_tag="KOU88_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBK3211416.1"
                     /translation="MIRYYKTIDSKLEKLSFFEDGCWINLVEPNHSEINEISNLLNID
                     VESIESALDEEERSRIDVEDNHTLILIDIPVDESDSNSSHYTTIPLGIILTEEAIVTV
                     CDAQTKILNDFIVGHIKDFFTFKKTRFLLQILHKNAAYYLHYLRKINKMTIIIEREIY
                     KSMKNKELVQLLELEKSLVYFSTSLKSNELVLNKMVRTAGIKKYPDDEDLLEDVIVEN
                     RQALDMAKIYGDILSRIMDAFSAIISNNQNNVMQILTVVTLIFSIPTIISGFFGMNVI
                     NMPFSNNPNGFWIILLITSIICIVITFFMSRNKLL"
     gene            complement(76059..77930)
                     /locus_tag="KOU88_001517"
     CDS             complement(76059..77930)
                     /locus_tag="KOU88_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBK3211417.1"
                     /translation="MKNTKFSIKKIKNISNDPKVVHTKGALLEKMGKMESAIELYKSA
                     ALDNYVKSQYTLGNIYESKKQFKEAEKWYSMAYKSGSEDAAFDLGNMYYKLDGYEYAI
                     YWYEKIANLGYLQAQNNLGVCHFKMKDFVRCEKWLKTAADKNLGKACFNLGVLYTFLE
                     KDDEAYEYYKKGSVLLDDDAKYNLAILNGKKKDNKSTVSLYKQLYKSGHMKGCFNLGM
                     IMEINDNLEDAEKYYKKSADRDDVKSEYRLAYVYDRKEELGDAIYYYEKAIEKNHTLS
                     KYRLANLYNRENEIEKAKTYYKMAAEDDITEAKNNLAGIYFEEKDYENAIKYYEDAIA
                     VGCKSSLENLGDLYYQNQDIEKAISYYSRIPNNVSCQIKLGNIYEDLNNIEEAISWYK
                     KASENGDTRSSYRLGCIYESLGNTKNARKYFEMASSKNHMNARIHLGRIYFREGKLEE
                     SKMMFDTPANENNVYAQHMVGLIYDMFYKDYVNSKFWYEKARAQGCVESIYNLGQIYL
                     KLNDDAEAEKYYKEGIKYGSKKCEYMLAGLYYKKSLDMYISLANEEYDNCEEIVEGFP
                     NLNIDFDEVLIPPFKLQEEVIDEEEYVPIYILNIKESLDSMLEGLETEMIIDEEHDS"
     gene            78120..79046
                     /locus_tag="KOU88_001518"
     CDS             78120..79046
                     /locus_tag="KOU88_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBK3211418.1"
                     /translation="MNFSNIFIQVAVLFIIILVGYFVRKFNLLDDHCTSKLSTLTMTV
                     FLPSMIISSMQINFDSKMIQKILLLLFTSLIMYIVSIIIAFLLKYILKCNDKKDLGIY
                     QYIVVFSNVAFMGYPVIEAVLGHEAIFYTAIFNLPFNLFSFTLGIYLLSKGSTSRGFS
                     IKSLISPATIAIVIGLFLFVTGLRLPQFINEPLEMLGSITTPISMIIIGSLLANSSAL
                     DCFVNKKLYIVTFIRLLVLPVIVYFILKGWINDKMILAIPVVISSMPAAANTAIMANQ
                     YDSNITLASQCVFFTTLFSVISIPFISILLLS"
     gene            79185..79331
                     /locus_tag="KOU88_001519"
     CDS             79185..79331
                     /locus_tag="KOU88_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211419.1"
                     /translation="MDMDLLFKIVFAIVAIGVSVKIIKTVASLAFKIALILLIILFVY
                     RMFL"
     gene            complement(79436..79960)
                     /locus_tag="KOU88_001520"
     CDS             complement(79436..79960)
                     /locus_tag="KOU88_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3211420.1"
                     /translation="MSKPIDITIRPIRREDAQAFNEIRRTYSVMRNTLALMSDRVDKT
                     EAMLASLGENDYMFVAETNNNGEKDVIGFAGLHVNSSPRLRHSAEIGISVAENYQGRG
                     VGKKLMEQLLDIADNWIMLTRVGLEVIVDNEKGLNLYKKLGFEIEGTKKYAVIRDGKF
                     EDVYIMGRYNKNLI"
     gene            complement(80013..80237)
                     /locus_tag="KOU88_001521"
     CDS             complement(80013..80237)
                     /locus_tag="KOU88_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211421.1"
                     /translation="MIIKLTKDNFNFRFKQYEGMFFHAEVVEGMESIRYKITKDKEGT
                     ELKEFGSTHIKDNMIYVPQVEAYIDLNSIK"
     gene            80434..81558
                     /locus_tag="KOU88_001522"
     CDS             80434..81558
                     /locus_tag="KOU88_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3810 domain-containing protein"
                     /protein_id="HBK3211422.1"
                     /translation="MSKKTKYFSLILFPIALLLNFIASKVPNIVEKYYSQFIDKIIVQ
                     ILSKVSGIFPFSLYEITMYIIVISIFLFLCCTLSTIFNKKKKLNIYLKNSILNILSIV
                     SIVYFLFVVLWGINYNRIPLETTLINNYNLKNNTSIQSKQYSVKELTKLYKFLVIKAN
                     ETRKLTLQDKNGIVKSNTDYNGVINRAQLGYDNILDILPSVSGSYSKPKYIISSNLMC
                     YTGITGIYFPFTGEANVNIAIPDLYIPCTVEHEMAHQRGFASEDEANFIAYLTSIKHP
                     NIDFNYSGYILALNYTASALSKVDYNAYVDISAGILDSVRRDLKNESEFWQKYEGKIN
                     EISNEFNNSYLKANGVTEGTQSYGKMVDLLLTYYELYPYN"
     gene            complement(82032..82856)
                     /locus_tag="KOU88_001523"
     CDS             complement(82032..82856)
                     /locus_tag="KOU88_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211423.1"
                     /translation="MRYKKISSLPILVVALLITGTTTTFSLSTTNSEKTNVYLANTVS
                     TVTKKVSDIQSSKGLVYNENIPLFINNSKIQYDDTPYHWPSNVISLTNSSEKAIMDYE
                     ITCLAYDKNGKPLELYWDAQNVAADGEVGSVGFSPAGVDYGIVTGISPVSPKSYSHTY
                     RKMQQSPPQDIISMFEKQQGKAWVENWLKEWKQMEKEYAKQNAIAPGKNQNDAFLLFD
                     KWKQSTGEHGVKYIISCVKQVTFNDGSVWKNSAYENWLKSFQGKEVSNSVLENYYK"
     gene            complement(83204..84259)
                     /gene="ispG"
                     /locus_tag="KOU88_001524"
                     /gene_synonym="gcpE"
     CDS             complement(83204..84259)
                     /gene="ispG"
                     /locus_tag="KOU88_001524"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBK3211424.1"
                     /translation="MSYERRKTREVSVGTVKIGGENPISIQSMTNTDTRDADATIAQI
                     KRLEEAGCDIVRVAVPDIKAAKNIAKIKSSVNIPIIADIHFDYKLALEAIEQGVDGIR
                     INPGNIGSIERVKMVVEKCKERNLKIRIGVNGGSLEKELLKKYGSATAEALVESAMGH
                     IKILEDLDFHNIVISLKSSDIYKTVDAYELISKKVDYPLHIGITESGSVHKGTIKSSI
                     GVGALLLKGIGDTVRISLTGDPVEEVIVGKQILRSLGLLNDKIKVISCPTCGRCNIDL
                     ISVVNEVEEKIGSMEKNITVAIMGCAVNGPGEAREADIGIAGGKGEGLLFKKGEIVRM
                     IDGNKLVDELLEEIEKL"
     gene            complement(84442..85446)
                     /gene="rseP"
                     /locus_tag="KOU88_001525"
     CDS             complement(84442..85446)
                     /gene="rseP"
                     /locus_tag="KOU88_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBK3211425.1"
                     /translation="MTIIAALILFSIIVLIHELGHFIFAKRSGIKVNEFSIGMGPKIY
                     SVKKDTEYSIRALPIGGYVSMEGEDEEQISPNSFGNKSILQRFSTIVAGPIFNIILAA
                     ILLVPVFLYIGSPTTKLGKIMPDTPAQAVGLQVGDKINKINGNSVKTWDEVANIINTS
                     SGGELKLSITRDGSDKVVNVTPKNNNGKYEIGIQPQREKDFLGSIVNACKTTVDMTKQ
                     MLTFLGQMITGRVPGGIGNAVAGPVGVIGMVSDAARTGIINVVYLAAVISLNLGIVNL
                     LPIPALDGWRILMLLLEAVRGGKKLDPNKEGMINVVGFGALMLFMLFITYKDILRLFQ
                     "
     gene            complement(85459..86613)
                     /locus_tag="KOU88_001526"
     CDS             complement(85459..86613)
                     /locus_tag="KOU88_001526"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBK3211426.1"
                     /translation="MKKISILGSTGSIGKQTLDVVREHRDKFEIVAISANSNIELLLE
                     QIVEFKPKYVTVFEENKALKLKEMLPKNIEIEVLAGMEGLKIISSLDEVDVLLTAVVG
                     MIGLVPTLCAIKKGIDIALANKETLVTAGELVMKEAEKYNVNILPVDSEHSAIFQCLN
                     GENKKNIEKIILTASGGPFRGKKKGELANITKNEALKHPNWSMGRKISIDSSTLMNKG
                     LEVIEARWLFGVEQENIDVVVHPQSIIHSMVQYTDSSIIAQLGCPDMRLPIQYALTYP
                     DRMESSFERMNFSKFSTLTFEEPDLETFPCLKLAYECLKMGGTYSSVLNSANEVLVSE
                     FLEDKIGFYDIPYYIEKTLEVHSSISEPTLEEILETDRWSRAYVANLIKK"
     gene            complement(86777..86980)
                     /locus_tag="KOU88_001527"
     CDS             complement(86777..86980)
                     /locus_tag="KOU88_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3211427.1"
                     /translation="MISYAPLWKLLIDRKIKKMEFVNISGISISVLGRLGNDKSVSMD
                     TMEKICLALDCKIEDVVEIKKGI"
     gene            87317..87898
                     /locus_tag="KOU88_001528"
     CDS             87317..87898
                     /locus_tag="KOU88_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211428.1"
                     /translation="MLYLLKINQFERSYDIGIFKNEQSIYKFIEKIPFVKKDNSNFNY
                     TNYYMEFEDIPEYYEVNFNNYLYIITRFSFIPDGTEIFFTWEEIHCWDEKVATEKTFI
                     NGETLVDSYNFPNNEVKDYIQKRESLYIETKKYYEEKGLKIERHALGSEDGEYVELTN
                     DSILYLLDIEAVEIREQSKNIEEFLYKYKKRFK"
     gene            complement(87986..89797)
                     /locus_tag="KOU88_001529"
     CDS             complement(87986..89797)
                     /locus_tag="KOU88_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBK3211429.1"
                     /translation="MKKKYDFLIYSAIWLVIIILFIFSLYHSIEHIKIISHTGTIRSE
                     TQKVVKQELNNERNDDLIKRLDNILIKLRTGNGENGFQRCDNKEFQQKLNQMDSMWES
                     MKKEIIKVRNGASGDKLYKLSEEYSVLSNQIVFISEKHSNAKLYSFATALFIYLIFST
                     ISLLIWEYYNKKRFKRIFYTDNLTKIKNQVAFENRAIEILHNASNKEYVLLNIDIDNF
                     KYINDTHGYEYGDKVLIIVATVLSKTFNIKETCARICSDNFVILAKYRDSLLEDIREM
                     LTNAIISELDMNVTQTISYCIGAYLVEIDNLGYKSINSIMDKANIAHKVSKTRGISST
                     VWYNENLLKQLQMENSIYNYMYKAIENEEFHMYLQPKFQISSLNVVSAEALVRWFSPE
                     LGFLSPDEFIPLFEKSGFIIELDFYMLKKACSFVKKTFMKKNQYTYPIAVNFSRVTIY
                     QNSFYQRFLDTVKEYEIPFKYIEIEVTESAFNEISQPVISILEELKKLGFLISMDDFG
                     SGYSSLSLLCSLSINGLKLDKSLLKETFNREKVYSIIQCIIEMSHRIGMSVVCEGIET
                     KKDLEFLNTVKCDVGQGFYFSKPIEEKEFFNKYVTKK"
BASE COUNT        29680 a        15644 c         9902 g        35034 t
ORIGIN      
        1 attggaaaat ataaaataca agacttacat ccggttcaca tacaaaacta catagataaa
       61 ctatcttata aactaaatcc tcaatcaatt aagattcata taaatatatt gaaacttgca
      121 ataaaaagag cttatagact caaattaata aaagaaaatg ttatggatag tatagaggct
      181 ccaagatata aaaaatttaa aaatgagatt tatgatagag aacaaatgat aaaattatta
      241 gatttagcaa aaaatacaga aatggaatta cctattaatt tggctattgg attaggtctt
      301 agaatttcag aagttttagg tctaacttgg gataatattg attttgaaga aaatacaata
      361 acagtaaata agataacttc ccgaattaat ggttctgtta ttctcaaaga gccaaagaca
      421 gaaagctctg ttagaaaaat atcttctccc aaagaattaa tgtctttatt aaaagaatat
      481 aaaataaaac agaataaaaa tttattaaaa tcttccatta gaaataataa taatttgttg
      541 tttttcaata agaaatgtga acctattgct gaagatgtta tgagtaaaaa atttaaaaga
      601 tttttagaaa agaatgaatt acctcatatt agattccatg atttaagaca ctcacatgtt
      661 actttactta taaattctaa agtacctata aaggttatat ccgagagagt aggacactca
      721 aatataagta ctactctaag cgtttattct catgtactta aagaaatgga taaagaggct
      781 tctgacaaaa tttctgaaag tttatttaat gctaattaat attaatttat cttagcttta
      841 aattagctta gcttattgag atagattcat taatattaaa tgtatctatc tcaaattaat
      901 aactacttaa ataatctgtt ttattttaat ttatcgcctc agttattata cttttttacg
      961 aaaaattata ctttacaata aaaaagatat tcccttatag aaaatatctt tttaaatact
     1021 atattattat atacttgcta acattggaat atctaacatc ttcttcatta catcatctac
     1081 tttttttgct ttatattcat tgtatccaat taaatatcct ttttcatatg aactttttaa
     1141 aatctctttt tcatataaat tatcagattt ggcttctgtg acacttaaat tataaagccc
     1201 tttacaccca tcttcataac ctttattata ccctttttct gcaaaatagt ttttatgatt
     1261 tttttcgtta tgtactgaag atattgttac tccagaattt tcttttgtac tagcataagg
     1321 acaaaaacct ttattgtgtt gatgtgctga atgtcctcca caataataac gtgttaactc
     1381 tgatttattt ttattatgat gacctcctga tgaattatgc cctcctgagt gagcatatga
     1441 aaaattccct acactaatca tagctaaact caatactaca gctactaacc ttttcttaac
     1501 cataatctat tccccccaaa atgttatata tttttattat atcatctact atattatatt
     1561 taaattctta atatacaaaa tattactcta ttctgctaat aaacatgttt aaacaacata
     1621 aaaaacctcc taatatttga ttaaaatttt acacactcat gcatagcatg tctcaaatat
     1681 taaaaggttt tatactaata attatttatc ttttccatac attttagcta attggtcttg
     1741 tatctcttta ctttctaaat actcatcaaa gtccattttt ctatccatta ttccatttgg
     1801 agttatctct ataattctat ttgctatagt agatataaac tcatggtcat gagaagtgaa
     1861 taaaagtact cctgggaact tttcaagtcc tttatttaca gaagttatac tttctaggtc
     1921 taagtggttg gtagggtcat ctaatacaag tacatttgca tttgaaagca ttagcttact
     1981 aagcatacat ctaacctttt ctcctccaga tataacttga gcttctttta atgcttcttc
     2041 acctgagaat aacattctac ctaaaaatcc tcttataaaa ctttcacttt tttcttcaga
     2101 gaactgtcta agccagtcaa ccaaagaata ttctactccg tcaaaaaact tattatgatt
     2161 ttttggaaga taatcttgag aagtagttac tccccattta tactctccac tgtctggttc
     2221 aagttctccc ataactatgt tgaaaagtgc agtagtagct atttcatctc ccataaatac
     2281 tactttatca tctctatcca atctaaatga cacattatca agaaccttaa ccccatctat
     2341 agttttagtt aaattgtgta cttctaaaac ttcattccca atttctcttg caggtgtaaa
     2401 tcctacatat ggatatcttc ttcttgatgg ttgtatatct tcaacttcta atttctctaa
     2461 ctgtttcttt cttgatgttg cttgtttagc ctttgaagca ttagaactaa atctagctat
     2521 aaattccttt aattgagcta tcttttcttc agtcttttta ttttggtcct tagccaattg
     2581 taaagccaat tgacttgact cataccagaa atcatagttt ccaacgtaca tttgtatttt
     2641 accaaaatct acgtcaacta tattagtaca tatttgattt aggaaatgtc tatcatgtga
     2701 tactattata actatagatt cttctaaatc cattataaaa ttatttaacc agtttattga
     2761 tttaaaatct aagtggtttg taggttcgtc cattaatagt atttcaggct taccaaaaag
     2821 tgattgtgct aacaatacct taaccttttc cccaccaact agttccttca tttgtttgta
     2881 atgcatatct ttcgttatgc caagacccat aagtattttc tcagcattag tttctgcatc
     2941 ccatccgtca agctctgcaa actcaccttc aagttcggca gcttttatcc catcttcttc
     3001 attaaagtct tccttcatat acaatgcatc tttttctttc attatgttcc aaagtctctc
     3061 atgacctctt ataacaacat ttaaaacagt ttcttcttca tattcaaagt ggtcctgttt
     3121 taaaactgac attctttctt tatcagttat agatatacta cctgtattag gctctatttc
     3181 tcctgataat atttttaaaa aagtagattt tcccgcacca ttagctccta ttattccata
     3241 gcaattacct ttagtgaatt ttaagttaac atctttaaat agttccttat caccaaatct
     3301 aagtccaaca cctgtaactt gtaacattaa tatattttcc tttctttttg ctcataattt
     3361 attttatcat aaaactttga taacattttt attatatatt atcacgtaaa tagtatattt
     3421 tttatactaa atttgtgaaa tatttattaa aataatacta aaaattgtaa atttataaaa
     3481 attaacaatc tcttatatta tacttataaa gaaatcaaat tgcaacttta ttcattcttt
     3541 tacacattga aaataagtta ttataatttc taaataaata tgcttttttt aaaacatcat
     3601 tctagctgtt ttgtttcata tttaaaaaga gtacttaatt tgtaaatact cttttttaat
     3661 aactttatat tttagcaaaa ttacatgcag gataagtaca tacatcacag ttcatacaaa
     3721 ggccaccatg accatatcta gctatatcat acttatcaag cttttcatca attaaaaccc
     3781 tagataaaac tatatcaaat actgtagttt tgtgatacat tgcgcatcct ggtataccca
     3841 taattggaac ttctccataa taagcaagta aaaacatagc tcctggtaat attggtgaac
     3901 catatgtcac taaatcagct ccagtttctt ttatagctgt tggcgtaaca tcatctgggt
     3961 ctacactcat cccaccagta caacagataa gttctgctcc ttgacttata aattctttta
     4021 ttgcactctt tataatctct ttatcatctg ggcatatagt ctgtcctata acttcacaac
     4081 caaagccttt tactttttct tctattactg gtccaaattt atcaacaatt ctgctataaa
     4141 acacttcatt tcctgtagta acaattccta ctttcttagg tttaaaaggt actacattta
     4201 ctatttttct attaccaact actttttttg catcttctaa ttttttctca tctataacta
     4261 aaggtatcac tcttgttcca gctactttta aacctttatt tactataaaa ttattatgaa
     4321 gagtagccat cattatttct ccaacacaat tcaaatcaaa aagtgcatca acatctatct
     4381 ttaatagacc atcacatgct gctataaaat ctattttccc ttcttttatt tcactaaaat
     4441 ctaaattttc tccagcagtt agttctttta aaaacaatgc tccttcattt tcatgaacca
     4501 ttccttctga cttttcccat acatacaaat tatctttacc aagagataat aacactggaa
     4561 tatcttcttc ttttactatg tggccctttt taaattttct tcctttaaat tctccaggta
     4621 ttatttgagt tatatcgtga cataaaactt gtccaacagc atctatagtt tttattagct
     4681 tcataattta cccccaattc tctcataatc catttttgta tcgatatcaa ataacatttc
     4741 tttaggaact tctacatact ttatttttga tgaatttttt aaaatggttt tacctttttc
     4801 atcttcttta agtgccaaca attcttcttt cttactatat gggaatatga ctggatttcc
     4861 acacatatct ttgtatcttg gaattactat aaaatctcta tctaatttaa aagtatttat
     4921 aattttatct atatataagt tatcaataaa tggctggtct cctacaaaga acatataacc
     4981 atcacatttt gagctattta aaactcctaa ttttatagat tcactttgac ctatatttgc
     5041 atttttatta tctatatatt caaaaccata tttattacac aataacaaaa cctcttcata
     5101 ttgacttact actacaactt gatgaaaatc aatcttgcta acttctctaa atacatgttc
     5161 tattatagaa cagcctttat aatttaataa aagtttattt gctcccattc ttctggcaaa
     5221 gcctgatgcc attatcactg catttatcat atatatcatc cttggtattt ataatatatt
     5281 gatagttcta tgatttttat aatatctcta ttgatattat ctatatatat aatatcatat
     5341 aaactatttt aatacttcaa tatcttacac aaaatttttg ttttacactt ccataaaata
     5401 tctctatttc actttcatat tctttaatat tttctattaa ttttatagct aaatttttat
     5461 atttttcatt ttcaacttta ttaataaata atactctttt tccagaataa tttttaaata
     5521 atccatttgg atttaatact atatttttta agttttcaat acttactgta gaactactat
     5581 taatactact tgtatctaaa tttgctattt ttttaaatat ttctactcta tgtatattct
     5641 cttcattaat attcattcca aatgatgtta tatctaatat ccctatggtt tttgtagttt
     5701 tatgatatac tactggttct ttagcattcc aacctttaag tttttttctc tttgagccat
     5761 ctccctctat taaaactaaa tcaaattggt ctacaatttc atccaaaata gaggaatcaa
     5821 tacttactaa tttattttca ttatttatat aactaccaca tactgttatt ccatgacaaa
     5881 tagatggaat aacagttcca tctattgtaa taattatatt gtcataatcg tttggtacat
     5941 atattttagt tgttgttgta agaagaactt tcaatttatc tctataaaaa tttgcaaaat
     6001 agtttataaa cgaagttttt cctcctgctc caactacagt tattatttca ttcttttcta
     6061 ttatatttga tagttccaca ctttcacctc ttataaccag ttttctaatc tcttaattat
     6121 tatagttaga cctttttagt aaaagtgatt tttgaaattc cataaactcg aaagtaaata
     6181 gattctgttg taaacaacaa ggcggatcca attcgccgct aagctgtaag cttacgctat
     6241 cagtttatct tttaaatata attaagatat tcttactctc tgtggttgct ttaatatttg
     6301 aggattattc tgtaaattag ataaattaac tacttgtgat ttttttagta tattaagact
     6361 cgcatttaca tctgcattta taatgattcc aacactggat ttgtactgtc cacgcgttat
     6421 tctttcccct ttaaagtcat attttttaac attgtccaca ttgatatcag gtagaaaatc
     6481 atcagcaaaa aaatctgatt tactagtata gctttcttct tgcctaataa aattgatatt
     6541 ttttatttta cacagatatt ctaattttcc ttttatctct ccaaatggga ttcttataaa
     6601 atttctatat atttttctct ccatattatc acttttttct aacttagcat tatatcctac
     6661 aattaaattt ccaatattat tttttacaca ataatcaatt atataaaaac aggttttatt
     6721 tacatagtct ttaacttgat tatttctctt attccaaact ttaaattgtt ttcttgttat
     6781 tgcagttata ttctttttta attttaaggc ttctatttta tcattctgtt tgtttgccca
     6841 ctgattcaca gattttagcc tttttccatc tatgataaaa ctatcaccta aattggtaac
     6901 acatgtacat aaattttcta aacccaagtc tatagctagt gcattttttt gatttgaaac
     6961 ttcctctgat tttggtattt cataacaata ctgaatttca aagaacctag ctttatgttt
     7021 aggtattatt cttatttctt taattttttt ctctagtata ttttgtggaa cttttatact
     7081 tactttccca tatagttttt taaatgctgg agacataggt acatttaaaa tcccatcttc
     7141 tttgattctt atttgaccta ttattatgct aaaaaatcct tctttatcta aatatttagg
     7201 tgattttatc cctctaaagt catattttcc ttctttggct aatttaatta atccaaaaaa
     7261 tgacctaaac gaactgtcta cttcttttaa tatttgttgc gctatattac tattgagaag
     7321 cttatagttc tcattttctt tgcatacatg ataattagct tcatagttaa gatgttctcc
     7381 ttgattgaaa taatgctgtc ttacattata tgtaccaaca ttatataagt tcttagctaa
     7441 gaagcacatc tctcgtagag cttgatattc ttttttagtt aagtttttta attgttgtct
     7501 ctgagttcca tagtgtatat tttttattct gtttgacatg aactcacctc ctttagaata
     7561 tactctacta gacattatat acggtatttt tacaaaacac catatataat gtccatttaa
     7621 ttactttatt ttacaaaata atttaaattt acttgctttt atacacctta ttatttatta
     7681 taattgttta ttattatttt tcatacccat ataaactttt tcaaaagtca taggaagctc
     7741 tcttaaacga actcctgtag cattaaatat tgcatttgct atagctggtg ctggtgtatg
     7801 tataactatt tctcctaatg atttagcacc ataaggacct cctgggtcga aattctcagc
     7861 aaaatctacc aatatatttc caacttcttt ttttgtagga actttatact gtaggaaact
     7921 atctgttaat aatctaccat ctttatcaaa tatagggtct tcatacattg caaaccctat
     7981 acccatcatc acaccacctt ctacttgtat tctagctaaa gttggattta taactgttcc
     8041 acaatcaggt acacatgcaa aatttatgac tttatattcg cctgtatttt tatctaattc
     8101 tatctctgca aatcctgcta taaatggttt tatttttttc aacatgccaa aagattctgt
     8161 tgcttccaaa actactggta catcatcact agcaaatcct attcctccaa cagattctct
     8221 acccaattcc tctaatagaa caaacttgct attatcattt ttaacaaaaa ccctgtcttt
     8281 tcccaactct aaatcttctt ttttaaatcc tagctttgac tctgcaactg aaagtaatat
     8341 atcttttaat ttatttgctg tctttattgt tgcatttcct gtaaccgttg ttgtacaaga
     8401 agcaaatgct cctgtatcat agggacataa atctgaatca cctgtataaa tagaaattct
     8461 atctacagta gtatttaaag cttccgcagc aatttgagct tgaattgtat cagccccttg
     8521 acctaagtca gcaagaccag ataatagttt atatgtgcca tcttcatcca ttcttatagt
     8581 gactgttgcc atatctacac gcggtatacc agaaccatga tttgctactg ccatacctac
     8641 tgctcttact ttgttgtttc ctatatcttt acatggatat ttatcatccc aattaattaa
     8701 tttctttccc ttttctatac attgtctcag ctcacaactt aatatttcgt cttcagctgc
     8761 ttttccattg gtatacctat ctattatatt tttaattcta aattcaagtg gatccattcc
     8821 aatcttatgt gccaattcat caatagcact atctattgca aatattccct gtgtagcacc
     8881 ataccctcta agtgctcctg ctggtaacct attagtatat actgttctag cattaaatct
     8941 aacagcatca atatcattat atattggtaa ggtattgtgt ccagattcgg aagaaacaga
     9001 gacaccattc ccaccataag cacctgtatt gtttaatgac tttagctcta ttgcttttaa
     9061 atttccttct ttatctgcac caactttaac atcaaaaaac atttcatgtc tactattaga
     9121 acctacaaaa gtttcacttc ttgtaaatac aaattttgct ggtctaccag ttttcatagt
     9181 aacaaatgca gtaaatatat ctgttgctgc tatattcttt cctccaaatc caccacctat
     9241 tctaggttta attactctta tttttgaaga cggtataccc aatacttttc taagtattct
     9301 ctttacattg tgtggtgatt gtaatgatga aactacaaca attctatcat ttatatcttt
     9361 atatgaatat gacctatgag tttccatcat gcaatgcgat tgactttggg ttttgtatga
     9421 agattcaacc acaaaatcac tttctttaag cttagcttca acatctccaa attcaaaaaa
     9481 ttcttttgat actatattat tttttgcatc caatccaaaa gggtatggct ctactatgtc
     9541 tttttctgga tgtataacaa cttcatttcc ttctgcttct cttgcatcaa acacaggctt
     9601 taaaacctca taatctacct ttatcatttt taaggcttta agtgctgttt tctcatcttc
     9661 agcagctact aaagctactt catctccaat aaatctaact gtatcttcaa gtaaaactct
     9721 atcataaggt gatgcttctg gttctgtttg acctggaaca caatatctga cctgtggtac
     9781 atctttatac gtataaatac ccacaacccc tggaattttt tcggcttttg atgtatctat
     9841 attctttatc ttagcatgag catgtggact tctaagtagt tttaatgtca aaacatcttt
     9901 atgcataatg aggtcttcag tatatagagg ttttcctgtg acaattgctg tactatctat
     9961 ctttcttatc cccttattaa tcattataca ttccctcctc aatagcatta tacatccttt
    10021 taactaatgc acttgccata tcctttctgt actctttact agctctcata ttacttccat
    10081 aagtaagttc cttactagca acaatagatg ccttatctat atctttttct ttatttaata
    10141 tattactcgc ttcaagtgct aatctagctt tttgaggtct tgccccaatt gctattttgt
    10201 aagtatcatt ttcttttagc attgctgaat ttaatacaga aaaatctcct gtgcattttc
    10261 ttattgagtc aaaaacagct attgcatctt tttttggtag tattacttcg accaatatat
    10321 ccctacttaa ttcactatcc aaaaactcac ttaactctag tattccttta ttgtataatc
    10381 tcaccttcgc tccaacaacc aaaagtgctg gtattaagtc agaaaagcca tactttgaaa
    10441 atacacttgc accaattcta gccccttgtc taaattgaac accaactata ttagaaacag
    10501 cacttgaaag tattccacta cagtaatttt ttatagtttt atcaatttct aaacttctaa
    10561 gtgaagtatc tgcacctatc aaaatatttt tttcatcctc ttttatataa tttagattta
    10621 tatcttttaa atctatcgct gttcctatat ttttattact taattttata aatccacatc
    10681 cacctaaaat aacattattt tttttagaaa ttaaaatttt atatgcttct tctaaactct
    10741 gcggaactga atattccttt atagtaacca tcttatcccc ccatcattaa cttattaaaa
    10801 cacaaaagtt tttaataaat cttttattta tatttataat tgtagtatat ttaattcaca
    10861 tatattaaac ctttacatta taaactttta tttttatcct caaccttatc acttttattt
    10921 ccaggaaatt ttaccatata taaagcttga attattatgg ctaccattgc tcctgaaact
    10981 acacttgaat ctgcaagtaa tgtctctata aattttggaa atttttcaag aacttgagga
    11041 gctaccatga atccaatacc agaagccata gaaagaccta atatcatgct attttcttga
    11101 ttaaatccat ccatactaac aagtcttaaa ccagatgttg taagagttga aaatataacg
    11161 agtgttgctc ctccaaccac acagggagga attgttctta ttaaattagc taataaagga
    11221 gatattcctg ccaaaaataa tccaattcct ccaatagcta gtacaaattt acttacaacc
    11281 tttgtattgg aaacgattgc agaattttgt ccaaacatcc ccattggagt tgcagaaaat
    11341 aatgcaccta ttgtagagag tactccattt cctaaaacag cagaagaaag ttcttcatct
    11401 gttacttgtc tattaagccc tcctaccgca gaaagtgtac aagcacccat tatatcagct
    11461 atctcaacta aatatattat tgaaaacatt acaacaactt caagtcttat atctagccca
    11521 aaagcaagtg gttttggaag tgcaaccaaa gtaaactcct gaattgaaga aaaatttact
    11581 atacccaaaa ttaatgataa aatgtatcca aaaattatgc taactaatat tgatgcatct
    11641 ttaaataatc cttttccata tttatttaat cctaatatca taagagatac agatattcca
    11701 actataaaat taattggatt cccaaaagtc tcattgccca tacccccagc taagtttttt
    11761 atagctattg gaaaaagtcc aagacccata catgcaacta ttgttcctga tacagctgga
    11821 gtaaatataa atcgtatttt tttaagacca aaaccaatta taattattac tataccagct
    11881 attatttgag agccaaataa tactggtagt ccatacttac ttgcaacaga taccccagct
    11941 cctataaaca tagctgtagc tcccattata actggtattc ctcctcctaa tttaaaacct
    12001 ttaaacaaag gtattggata taattgtaat aaagttgata atcctgcaaa aactaatgcg
    12061 gcttgaatca ataatgttga catcttatga ttaagtccag ctgcatttgc aatcaatatc
    12121 gctggtaaac aactacctat taccattgcc attaagtgtt gtaaccctaa aggtattgct
    12181 tcctttagtg gtggtattcc gtctaattca aattttgatg tactttttgc tttcataata
    12241 aaaactcccg ttacataaaa cttattgaat tatataaata cttaaaaatc taatatatta
    12301 aattaatgat gttcataaat atcaactata ctccaacata tatttaagtt tttagtctta
    12361 aaaaacagat gcaataaatt taattattaa caaataaacg tattctttaa ttttgtatac
    12421 attatatacc atgctttaca aatataagag tattatagct atgaattttt aattttttat
    12481 agtaaattta attcaattta aatctttcaa tcttaatcat tataagttat aagttttcat
    12541 aagtatttac atgtttcaag ttttaaacat ttacctataa acgctacttt atagatgtca
    12601 cttcaaatcc agtgacctca tactttcata tgagcgtaga ctatttcttc atcttcagca
    12661 ttacctgcta agagcaaccc gtttccacta tcaatcgctt atagtgtact ctctctcgag
    12721 atagtcgttt gaccttccta tttctaggct tggcgaccaa atgtccattt ttaagtactt
    12781 aggctctcac catataccat cctcactatt gtttctggtt ttcaccacat tcataaaagt
    12841 ttctttctat cttttattgt agttgcaagg ctttaggatt tactggtttt aaagttgtgt
    12901 cctacataga tttctctatg tacggggcca aaagtacaat ttatttaaca tactttgctt
    12961 taccccctgt aaataatatt atttactctt tcactgtttt tgttattaaa ttaattaaat
    13021 atcaattaat ctaagcataa aataattatt taatttaaac tcaaaatatt tatgaatatt
    13081 ttataatata attctcataa gacagaaaaa cttaataagc tatgtatctc agttgtacca
    13141 atgtactctc ctttactata tttgtatctg caacataaaa tatacaagtt tctatctatt
    13201 tatagatata tatatctata agcaaaatag taatattatt tttatagtaa aaattttatt
    13261 catattacta tttataattt ttatagagca attttagtgc caatatttgc atacatttgt
    13321 atagtataaa atttttatgt tctcattgat aaaattttac ttatttcaag cgttctatta
    13381 gattttatca tctaaatttt aggttttatt tttataaatt aattgtattt acataaaaaa
    13441 aaagacctaa aaacaaattt ttaacggtct tttctcaatt ttttattttc atttctaaaa
    13501 tttataataa atagtaagaa cactataaat tcttttatat aaaattctta gtttgtggat
    13561 gataaattag tgaattaaaa tactacttta ctgattttag tttgacaata tcactccaat
    13621 ttttactagt ggctaactct actaaattta agtctcttct tatttcagct atatcctctt
    13681 ttatagaatt agtgtcacct tttatatatg ctatgttatg ttctatatta tcatgagtag
    13741 ctttatttat ttcagaatta tgtaataaac ttcctaaaat attattctgt tctatctgta
    13801 tctctttcat tgatttatct tcacattcta gactatcaat cttaatttca attccatata
    13861 atttttcatt tgctatggat acctcgtcct taattccatt catatcttca ttaatgttat
    13921 ttattttatt ttgcataaag tttacttctg atttaacttc ggaaacatct tctttcatta
    13981 cagttatttc ttgtcttact tctgacatgt cttttttcat tacatttatc tcttgtttta
    14041 cctctgatgt atcttctttc attacagtca tttcttgtct tacttcagac atatcttctt
    14101 tcattatatt tatctcttgt cttacttcgg acatatcttc ttttaataca tttatctcct
    14161 gttttacttc cgacatatct tctttcatta cagtcatttc ttgtcttact tcggatatat
    14221 cctctttcat tatatttatc tcttgtctta cctcggacat atcctctttc attatattta
    14281 tctcttgtct tacctcggac atatcttctt tcattacaat catttcctgt tttacttctg
    14341 acatatttcc ttttaataca tttatttcct gttttacttc cgacatatct tctttcatta
    14401 cagttatttc ttgttttact tccgacatat cttcttttaa cacatttatt tcttgtttta
    14461 cttccgacat atcatttttt atgctaacta catcttcatt tatagtatat aataactcta
    14521 aaatcttctc ttgcacttgc atcaccatcc ctattaatta ttataacatt ttacacaaat
    14581 gctatacaat gttaacatat atatcagaat tattaaaatt ttaattaaac aaaattgatt
    14641 cactttatta cttcaaaact aattaatatc taaaataact acaaataaac aaaaataagg
    14701 tcaacaacaa aaaaggctta tctctttgag atagcctttc ttatttttat ttaaaacttt
    14761 gttttttata aaataatcta tacattcagc tctgaacatg aaatttttct tccaagtgct
    14821 tttggtttac aaactgatat acaaagtcca caatatctac actcttcttc attcaattcc
    14881 atcttatcat tcaattttct cgcttgatat gcacaaactc tctcgcacat cttacattta
    14941 gtacattttt cttcatcata agtaaactca aagctaagtc tttcattaac atctcccata
    15001 tgattatgta ctataccaca agcattttct atagtattat atcctaatct attaagatta
    15061 gattttaaat catcatgtat tttagatatt acttgtgcgc cttttaaaat tactactgaa
    15121 catataccaa caaagtcagc acctgccata atcatttcta aggcatcatc tccacttaca
    15181 catccaccta agccaattat tggtatatta acttgttttt ttatttcata tattctctgt
    15241 aaagttattg gcttgatagt ttctccactt aaatatccta ttccatttcc acctaataaa
    15301 ggttgccctg tttctatgtc tattctaaat gctggtccta cagagtcaca agcagttatt
    15361 gcatctgctc ctgcttcttc taatttttta gcaaaatcgc ctatctcatc tatcatagga
    15421 ggaagtttaa ctattacagg tatatttact ctttcctttg catctttaag cattggtatc
    15481 aaatctctat agtcataaga tactaattca ataaagtcag ctcctgcatt tgcaactttc
    15541 tctactaatt cgctactttc ttcaattgta tgacctattg aagctataca gacagtccca
    15601 tctcttttca tttgtggtat ttcaaaatct atccattgct ctggctcaaa atctgtccat
    15661 ttttcattat ttaaaagagc attagctgta tttctaacca tatgtggtgc tggatttata
    15721 gctctttctt ttcttatagt cttagtcaca actgcccctg ctcctgcatc acttaatatc
    15781 ttgcatccag ctgcactata tgttaatggt cctgaaccta ttataagtgg tgattttaat
    15841 tctttaccta aaaaattata cattatctgc ttcccctttt catatatatt tacattcgtt
    15901 aaaatttcca aaattcacaa gcaacttctt tcatttcttt aacaatagct tttttatcta
    15961 aatcaactaa ctgtttttct tttaaaatat gtctaccatc tatgtataca tttgatataa
    16021 attctttttt accctgaact actatctggt caaatatatt atcaagagtc acaggagttt
    16081 taaattcatc ttccataact attatatcag ccttattacc aactgctatt ttaccagaat
    16141 tttgaagtcc taatacataa gcaccatgct ctgttgccat tctaaatact aaatttgctg
    16201 gcattactga tgcatcttct tcaactgatt tatgcattaa aaatgcacct ctcataactt
    16261 caaaaaaatc atttatatat ccatcagtac ccagtgccac ttttatgcct tttttaatca
    16321 tttttggtac tggagaaaaa cctccaccta cttcacagtt actaagaggc atatgaacca
    16381 cttttacgcc tttttctttt aatatatcta tttcttcatc atttactttt acacactgag
    16441 atgctaatac agtttcatcc aatatatcta aatcattata gtagtcaact gcttttttgc
    16501 caaagtgttt ttcagcatag tttggctcat atatactctc acataaatga aattgcattg
    16561 gtgcatttaa tttttttgca tcttctttag ctttcttaat aaatctatca gaacatgtga
    16621 agcttgtatg tgtacacatt attccattta ttaatttact attttctcta ctccacttta
    16681 ttaaattaga attttcatct aaacatctaa gtccattttc aaagcttatt ctttcacaac
    16741 tttctaagga taaaatcgct ttcatgccta tttcttctag tatttttcct tgctcaatta
    16801 aagttccttc ttctgtattt ggagcttcta gggtatcaca aaaagctacc acaccagatt
    16861 ctataagttc tattgctgat gctttagttg ttgccttcac ttcttttaat ccaattctat
    16921 tttctataaa tggccaccaa tagtcattta aaaaaccttc aaagtcagta aaatgtacat
    16981 ttgccggtat tcccctagaa agaactccat attgatgcat atgaccattg acgaatcctg
    17041 gcattattat agcatctgat ttatctatta tttcttcaat atttttatat tttatttcaa
    17101 cttcttcatt tggcaatata tcttttataa tgtcattttc tactacaaca gcagaatttg
    17161 tatatatttc atcagcagaa gatattaagt atttactttt aatagcaatc atttatttac
    17221 ctccctgatt taattttttc atggccatat aaactttctc agaagttata ggaagttctc
    17281 ttatacgaac tcctgtggca ttgtatattg catttgctat tgctggtgca ggtgtatgaa
    17341 taactatctc tcctaaagat ttagctccat atggacctgt tggctcataa ttatctacaa
    17401 aatcaacaat tatgtttcct atatcttttt ttgttggaac tttgtattgt aatagattag
    17461 aagtttgaag ctttccatca gaaccatgtc tagggtcttc atacattgca agccctatac
    17521 cttgagttac accaccttca acttgtattc tagcaagtgc aggattcata acggtaccac
    17581 aatctgtaga acaagcataa tttattactt taaactcccc tgttgtttta tctaactcta
    17641 tttcagcaaa tcctgctaag aatggtttag cactctcttg tataccataa gattcagatg
    17701 aatataaaac ttcttgattt ccaccaccaa cagattcttt tcctaattca cttaacaaaa
    17761 caaacttctc tacatcttca ctataacaaa ctctgtcttc atatagtatt aaatcatcta
    17821 ttggtaaatc gagtttcttc tgtgctactt ttaatatctt ttgttttaaa ctttcagcag
    17881 attttattgt agcatttcca gttacataag tagtacaaga agcgtatgca ccagtatcat
    17941 atggacacat atctgtatct cctgtataaa cggaaattct atcaatagat gtattcaatg
    18001 cttttgcagc tatttgtgca agtattgtgt cagaaccagt tcctaagtct gaagacccag
    18061 aaaacaactt ataagttcca tcttcatcca tcctcatatt tactattgcc atgtctatgt
    18121 tggctatacc agaaccatga gttcccacag acattccaac agccctcacc ttattgttgc
    18181 caatatccct aacagggtac ttttcatccc atccaataag ttttttacct ctaattatac
    18241 attcatcaag tgcacaactt cttattggaa aattcattat tccgccttca gtttgttttt
    18301 ttataatatt ctttaacttt atttctgttg ggtccatatt aagtttatgc gctaattcat
    18361 caattgcaca atcaagtgca aatgtacctt gtgttgctcc atatcctctt aatgctcctc
    18421 ctggaactaa attagtatat acagttctcc catcaaattt tattgcaggt acattattat
    18481 atgttggaag tacattatga cctgattcag agcaaactga aggtccatta tcaccataag
    18541 cgcctgtatt gttcaatgct ttcatatcta tagcttttat gtttccttct ttatctgccc
    18601 caatttttat atcaaaaaac atctgatgtc tagtattagt cattgcaaaa gtttcttctc
    18661 tagtataaat tagttttgct ggtctttttg tcatccaagt tacaaatgat gcatatatct
    18721 ctgttacagc tatgtttttt ccaccaaaac ctccacctat tcttggtttt attactctca
    18781 cttttgaaag aggtattccc agtgctttag aaacctgtct tctcatatga taagctgatt
    18841 ggtttgcaga agttactact aatctgccat tcgtatctat atacgtataa gctctatgag
    18901 tttccatcat acaatgggct tgtgattgag tcatataaga atgttctact attacatcac
    18961 tttctttaaa ctctttttct acatcccctt tacccatttt ttctctcgat acaatatttt
    19021 ttgtagcatc caatccaaaa tcaaatggac aaaacaaatc atcttcttca tggattaaaa
    19081 ttttatttcc ttccgattct cttgcatcca atataggagt cattacttca tattcaactt
    19141 ttataagttt catagcttta atagcagccc tttcatcttc agcggctatt atagcaactt
    19201 catctcctac atatctaact acgtcttcaa gtattaattg gtcatgaggt gatgcttctg
    19261 gatatgactc tccaaccatt gaatatctat aatttggaac atctttgtaa gtgaatatgt
    19321 ttactacacc ttttaccttt aatgcatttt ttatatctat gttttttatc ttcgcaaaag
    19381 catgtggact tctaagaagc ttaattgtta aaacatcttt atgaaaaatt aaatcttctg
    19441 tatatattgg ttttccagta acaatggctt cactatctat ttttcttacc tctttattta
    19501 ccatcacact cacctccaat actattatac attctcacta ctaaggcttt tgccatatct
    19561 tttctgtatt ctttacttcc tcttatatta cttccaaatg aaagttcttc acttgatact
    19621 tcaccagctt tttctatatc attttctaaa cttaatattt cacttgcttt ataggcaatt
    19681 tttgctcttc ttggtctagc gcctattgca attttataaa tacttccttc ttttaacatt
    19741 gctccattta atactgcaaa atcacctgta cattttctta tagaatcaaa tacacctata
    19801 gcatcttttt taggtaatat aacttctatt aatatatctt tttcaagctc actttctaaa
    19861 aaatcagcta agttcataac ccctttttta tataacttaa cctttgcatc taccactagt
    19921 aatgaaggta ttaaatctga aaatccatac ttagcaaata cgctagctcc tactctagct
    19981 ccacttctaa attgaactcc tactatatta gaaacagcgt ttgaaattac cccattacag
    20041 taatttttaa taaccttatt taattctaaa gttcttaaac ttgtgtctgc tccaattaat
    20101 atgctatcat cagtttcatt tatataatct aaagctaagt cttttaaatc tattgctgag
    20161 ccaatatttt tactacctag ttttaaaaat ccacatcctc caagtattat gttgtttttt
    20221 cttgatatta gcagttcata agcttcatct aaactttttg gaactacata ttcctttata
    20281 gttatcatac tctctcccca tatcaactta attttcactt aaaagtctaa gtgtttaaat
    20341 atttatgtat tgctcttaat tgacctttat atcctgtaca tctacaaagg ttaccattta
    20401 cataatctat aacttcttct tctgttggat tttgaagctc tcttttcatt gccaaaacca
    20461 tcattataaa tccaggagca caaaatccac actggtcagc cccttcgtct gcaagaaaat
    20521 ctccaaactt ctttgcttca tccaagacac cctcaagtgt tgtaatatgc tgaccgtcta
    20581 ctctagcagt aagataatta catgaaagca cggccttgtc atttaccatc actgtacata
    20641 acccacatga gcctgtatca cacccttttt taacacttac atatccattt tctcttaatg
    20701 tatctgctaa aaaatcatct ggtcttatac ttaattcttt ttctttatta tttatggtac
    20761 atttgataat caaataaatc acctcaaaac tcatattttt aagctaaagt tttactatac
    20821 ttttctatga ataaattaca tttattaata aaggctattc catttatgac cttccattct
    20881 attttttata gttcctctta cacaaagtct ctcagctgta tcttgagcat cttttaatgc
    20941 tttctcttca ttagctgtca atatttttga atcttccatt attatatttc catctactat
    21001 aacactctct atatttttca tactagaaga atatactaat gtagataccg gattatgcat
    21061 aggtatcgct tttggtgaaa gcattggatt aaatattagt aagtctgctt ttttacctat
    21121 ctccaatgaa cctatctcat cttccattcc aatagctctt gctccatcta tagttgccaa
    21181 ctcaagaact ttttctgctg acattgctaa tgggtcacac ttattaactt tatgttgaag
    21241 tgctgttaat ttcataagtt caagcatatc ttgagagtta ttactagcgg ctccatctac
    21301 tcctaaacta actgttattc cttttttaag catttctggt actggtgcaa cacctgaaga
    21361 taagtacata ttacttgctg tattatgaga cactttcata tcgtattttt tagtaagttc
    21421 catatctttt tcagttagat acacacaatg taccataagc acatttggtc caagtattcc
    21481 taatttttct aaaacatcta tgtcatattg cccatgcaat tcttttgctg cttctctatc
    21541 aaaaggagtc tctgatatat gtactgtaaa taaagcatca tcatattctt ttactactct
    21601 ccatagcatt tcaagcattt cttgagaatt tgaccatatt gctgcaggag ctactcctat
    21661 tttgattctt ccattttctg tattatggtg tttttcaaac aatcttctta catctttttc
    21721 aaccgtttct acatcttgca ttattccagg atgaactcca aattgagctc ctgtattcat
    21781 acatcctctt ccaagtattc ctcttattcc taattcttta taagcatcta ttattccatc
    21841 acaaagacct ggcttactat gaggatacat gtagtcaacc attgttgtta taccacttct
    21901 aagtccttca atacatccaa gcattgcagc atcataagta tcttttggct ctaaatagtt
    21961 agctgctgga aatgtcatag tttctaacca gtctttaagt accatatcat ctcccaatcc
    22021 ttttaataaa gtttggaata aatgattatg tgtatttata aaacctggga ataaaacttt
    22081 acctttagca tctataattt ttttaacatc agtatattta ctttctatct ctttagaatt
    22141 tccaatatca gcaatcttgt tatcttttac tactaatgcc ccatcaaaaa taacttctct
    22201 ctctttattc acagttacta ttatggcatt cttaataagt atatccatca ttcttatttc
    22261 cccccgcatt atttagtaat ttttctttta atatattgac ctgttggatg ttctttaaca
    22321 ttacaacttt gtactacatg atttcctctc aaaaatacat cttcaacttt acatttaacc
    22381 ttaaatcctt catatggagt ataatctaca ttttgttttt gagttttata actaattgtt
    22441 tcttctttat tgatatttaa aatgactata tctgcatcac ttcctacagc tatctcacct
    22501 tttttaggat acattccaaa tatttttgca gcattcgtag aagtaacttc cacaaactta
    22561 tttacactta ttctattttc taagacccca tatgtatata aaagtgctaa cctatgttca
    22621 acaccaggtg ctccatttgg tatcttactg aaatcatcaa ttcccaagtc tttttgcccc
    22681 ttaaaattaa atgaacagtg gtctgtgcca actgtttgaa tatctccact agacaatcct
    22741 tcccaaaggt aatttatgtc ttcttttttt cttaaaggag gagacattac atacttagca
    22801 ccctcaaatt tatccttatt atataaattg tcttctaata atagatactg tgggcatgtt
    22861 tctactatca tatctatatt tttttctcta gccattttta cagtttcaag tgactcccta
    22921 caacttaagt ggactacata ggattttgaa ttagataatt tagttatatc agcaagtctt
    22981 gaaacagact ctttctcaac tatgttaggt cttgtaagtg gatgatattt tggctctaaa
    23041 ttaccatttt gtatattttc ttctatcaat acatctagta aatccccatt ttcacaatga
    23101 aatccaacta tacaacctaa atcccttgct ttctttaaaa ccctgtatat tgttccatca
    23161 tctactttca tgccatcata tgccatatac atcttaaaag atactatccc atctgaaata
    23221 agtttttcca tatgattaaa tgtatcttta tttaaacatg taattgtcat atgaaaacca
    23281 taatcacaat aacaatttcc acttgctttt ttatgatatg cttctacacc ttgcagtagg
    23341 ttttccccct cattggcttc tgcaaaatct agtattgtag tagttcctcc agctatagct
    23401 gctcttgttc ctgtttcaaa attatctgca gttgtaatag aacctgcatt catatcaaaa
    23461 tgagtatgtg tgtctattcc accaggaatt acaattttac ctgtagcatc aataacctta
    23521 tcaccattta tttctaagtt atttcctatt tcaactatct tttcatcttc tatccttaaa
    23581 tcacttatat aagtcttatc agaggtaatt atagttccac ctcttagtat tgttcccata
    23641 tatacctcct aacttttaag ctttaaagta ttttctaagt attgtaaaac tttatttaaa
    23701 attgtatttt ctaaaggtgc tatattcagc acctctagac tatatttaaa taatttattg
    23761 tgaactaaat attattttcc gtatacagat tttaatattc catagtaacc ttctgttcct
    23821 acaaataact gttcttgctc tatatactca tctattgtgt gagcaagatt ttccttagaa
    23881 ggaccaaatc ctatagtttt tattccagct tcacctgcat agtgacttcc attcgtacag
    23941 aatgagtatt gagttatttc tgaatctatt ccagcttctt ttaatccctt atatgctgct
    24001 tgaacaaatt catcttcttc gtcatataac caacctggga agaatctttc actttctata
    24061 gtatttcctg tatagcaatc agctttttca accgcataag aaacttttgc atttaattct
    24121 gggtcttctt tcatcatttc atctaataaa gcttgtattg gagctaatac gccttctctt
    24181 gtttctccaa ctaataatct tctatcaaaa gtagctttgc aataatctgg cactactgat
    24241 gctcctggat atggagaaga ttttatatct gttaaaacta atattccatc acctaaaact
    24301 ggatgagttg gaggtactaa ttgttgtatc ttttggatta cactagccat tttataaact
    24361 gcatttacac ctttttctgg attagcagag tgagctggtt taccaaaagt ttctactact
    24421 atttctcctc tacctctctg accaatcttt aagtttaact ctgaagactc acctattaca
    24481 acatagtcag gttgaacagc cttacttatc tctctagctg aaacaccttc aaatatttct
    24541 tcatgaacaa cacctgctac atatagttct ccagcaaaat ctctattagt gtctttagca
    24601 aaatacgcta cagcagacat cattgcagta tattgacctt tcatgtcaga agttcctcta
    24661 ccatatatct ttccatcaac tatttttcct tcaaaaggag gaacactcca tttacttgca
    24721 tctggaactg gaactgtatc tatatgtcca tcaaataaga ttttcttacc tggcttgtta
    24781 ccttttatac atcctactat atttccatat ctatctcttg accaactatc aaaacctaat
    24841 ttttcaaaag actcttctat tgcttttaca acaccttctt catttccaga agaactagga
    24901 ttttgaatta atttttggca tatttcagtt acttcttgtt ttctttgttc gtttaacatt
    24961 tcattatccc cctagatttt ttataatgta tgtattttat atacttatat attttctaaa
    25021 ttttagaact tatatatctt ctaaatatgt aaaccaatat ctaataattg cattttagta
    25081 attccttata tacttggata ttctccatcc caaactatac ttctatattt gtcagggtca
    25141 gtatctcctt ctgtgcttat taaaagtatt cttgaatttt catctaattt taaatctttt
    25201 cttaaatctg ctaaatcttc tctttccata gctgctacta aaagaccagt tgtaactgct
    25261 ccagattctc cagaaattac cttttcatca ccatttaaag gattacctaa tgttctcata
    25321 cctttagcag aaacccagtc tggtgctgaa acaaatgctg ctgcatgatt ttttaatact
    25381 tcaaatccta tagtatttgg ttctccacaa gcaagccctg ccattatagt tggcatatct
    25441 cctccaacaa atcttggttt tccatctcca gcttctgctg atttatagta acaatcagct
    25501 tcgtcagcct ctactactac tgttattggg cattcatcat atattgaagc aacataccct
    25561 tgaactgcac cagcaagtga accaactcct gcttgaacaa atacgtgtgt tggtctatct
    25621 actccatatt cttttaattg ctctatagct tcttgagcca tagttccata tccttgcatt
    25681 atccacgctg gtatttcttc atatccgtcc catgctgtat cttgaaccat tactccatgg
    25741 tcatcagctt ctgcataatc attagctaat cttactgcat catcatagtt taagtctgtt
    25801 atactagcat ctgcaccttc tcctttaatt ttatttaatc taaattcaga agaacctttt
    25861 ggcattaata caacagattt ttgacctaat ttattagctg tccaagcaac tcctctaccg
    25921 tgatttccat ctgtagctgt aaagaaagtt atttctccta atttttcttt tatttctttt
    25981 gaagttaatt tgtcataccc taactcagat atatctgtat ctaatctttg agctaagtat
    26041 ctacccatag aataagaacc acctaatact ttaaatgcat ttaatccaaa tctataagat
    26101 tcatctttta catatactcc tgcaacacct aatttttttg ctaaaccttc taggtttgct
    26161 aatggagttt ctttatattg aggaaagctt ttgtgaaaat ttctaacctt agttatttct
    26221 tcttcattta aaaatttgat acaattttcc ttatcgccct ttggcaaatt atttactttc
    26281 catttaattt cttttaacat ctaaaatacc tccaaattat tgttaaattt ttatacttta
    26341 atatataagc aattaacatg ccaatactaa atatatacta gatatttttc catgactctt
    26401 tagtatagaa attgcaatgc ttttattatt ttttcttttc tatctttagt tcatacaatg
    26461 tatgtagaat ttaataacta aaaaaccttt tctatcttct cactttttaa ttctcatttt
    26521 taaaatttaa aaataaatct caaaacactt tgtttctata ttttttaata taaaatttat
    26581 aaaatctaaa ttaaaacata aaatagtgat gcaataatct attacatcac tatttgtata
    26641 tattcaataa tataataaat ctttagtggt ctctaagagg tgatttttca tcttttttaa
    26701 catctaattc ttcttttacg acattccatt tttcaagacc aaacttagaa accataactg
    26761 cctctgctgc accttttcca agtcttttta ctgtgtccat acctgtctca tcctcttggg
    26821 caccttttgc ttttccatct ttactccata ttgtaccacc tatatagcat ccacctaaac
    26881 ctccagacac taacatttca tgcattagga agaaatttat tataggaagt tttgtcaatt
    26941 cttggccacc atatctagtt ccaccagtag ttatagctgc accaacctta ttttgaagtt
    27001 ttcctggatg aactaaatac attggacgaa gtctattaaa tactgctgta agttgagcag
    27061 ttatattcat atcataaact ggagaaccta ctataattcc atctgcctcc aatatttttt
    27121 gctctaattc ttggatatca tcttttataa tacacatagt ttcttttctt atacatgcat
    27181 cacaatgtac acaaggactt atttttttcc ctctaactga ccaatactca gtttctatac
    27241 caggtatagt ttctgcttct ttcaaagctt ctaacactgc atattctgtt gctcctttac
    27301 gtggacttcc acaaatacct aatatctttg ccataataat atctcctcac caaataaatc
    27361 tatttttatt atctatttac aaatacaata aattgttatt tctgctttaa tttctactat
    27421 tttaatttta ttggtaatga atgtatctct acatcagttg cattatatac tgcatttgca
    27481 acagctggcg caactggtac aacggcacat tctccaatac tcttaccacc aaaaggccca
    27541 gctttttcat aaccatctac aaatgcaact tgacattttg gcatatctac agttctaaat
    27601 aatttatatg ttttaaaatc agtagcttta ggtctacctt gttcatcaaa tgccaattct
    27661 tcactcaatg cgtatcctag acccatatga atcccacctt ctaattgtcc ttctaaattt
    27721 agaggattta taactctacc aacatcatgt acagctacaa aatcaactac ttttatatcc
    27781 ttagtttctt tatctactaa aacttcagca aaatgtacac cataagaagt acgtccagct
    27841 ggtgaagaat aatcttcaac aacagttaac tctcttaatg atttactttg actatatact
    27901 gcgacatcag aaagtgatgc ttttacattt tcatcaagtt tactaattac atatccattg
    27961 tctagatata aatcttcttt tgatgtttca agtaattttt ctgcttcttc taatataaga
    28021 tttttcaatt tctctgctgt ctttttagct cctccacctt ctacaaatac ccctctactt
    28081 gcatagtcac caaggttgaa tgtacatgca tccgtatcag tttcaaatgt atcaacttta
    28141 tcaggtgtta ttcctaaaac ttcagctacc atcatcgttt gcatagttac aacaccatta
    28201 cccatatcat gagctcctgt tagtagtgtc aacgtaccat cttcatttaa tttaagagtc
    28261 aatgtaacaa catctctatg tgcaccaaaa actccattac catgtgcacc tattgccata
    28321 cctatacctc ttaaatattt tccttcttct tttggaagtt ttttcttttc atcccactta
    28381 aatatcttct taccttgctc tatacaatcc aatactctag gatttccaag agaaccgtgg
    28441 aagattatat cgacatcatc tggctctact gcatttttat tttgaaaatc gactaaatcc
    28501 atacctattt cctttgctat tttcgcaaat tgagcttgtt gagccataaa tatttgaggt
    28561 gacccatagc ctctcatagc tcctgctatt ggtgtatttg tatatacagg catcccagta
    28621 aactttatat ttggtatttt ataaacttta aatactttat gactaagtgc tcctataaca
    28681 tttaaagcac ttgatgcata tgctcctgta tttgtatata tttttatgtc ttgtgctatt
    28741 acttcaccat ctttatttac accagttttt aattttacaa aagacccatg acgagttctt
    28801 gtcgatatca tagattcctt tcttgtaaga accattttaa ctggtcttct tgtcattttt
    28861 gataatgcgg ctgctactgg ttcaattgta agttctaatt ttccaccaaa tgagcctcca
    28921 atagcaggtc ttataactct tactttattt aatgacatcc caaaaatttg agatagtatt
    28981 attctaaatc caaatgtatt ttggcaaggt gtatgtacag ttaatttatc attataatca
    29041 tagtgtgcaa ttacactatg agtctctatt gcactatgat gtattgctgg agtagagtat
    29101 tcatcttcaa atatatagtc acattccttg aagccttttt ctacatctcc cccatttatg
    29161 ttgttttgag aaactatatt tgaatctcca tgtatgcaga tagcatcttc ttttattgca
    29221 tcttgtatag taaatacagc tggcaattct tcatattcaa cttttataag ttttacagct
    29281 ttctctgcta tttctggagt ctctgcagct actgctgcaa cacggtcacc aacaaatcta
    29341 actgtatctg aaaatataac ttcattttca ggtattttgt gctcataaaa tcttaatgaa
    29401 ccattgtatt ttctttgtga tgtattgaga taagtagcta tagctctaac acctactact
    29461 ttctcagctt cacttgtatc taaacttttt atttttgcat gtgctacagg gcttaaaagc
    29521 atcttagcgt aaagtacatt ttgtggtttc atatcagcca cgtatttcat ttgaccagta
    29581 acttttaaag ctgcatcttt tagagggtat gattttccta ttaccttttc cataattatc
    29641 taccccctaa tctagctgca gataatttta cagcttctat aatctttaca tatcctgtgc
    29701 atctacagag attttcttta aaagcttctc taatttcatc ttcattagga gatgcatttc
    29761 tatttaaaag agcttgtgtt gttataatca taccaggagt acaatatcca cattgtacag
    29821 ctccgacttc tataaaagct tcttgtattg gatgaagatt ttctccatta gcaaaacttt
    29881 ctatagtgta tataacttta ccttcgcagt tttttgcaag aagtttacaa gatttcatgt
    29941 caactccatc tatcaaaact ttacatgctc cacaactgcc actattacaa ccttgtttcg
    30001 ctccagttag atttaatttt tcacgaagta catgcaaaag agtttcattc ttttcaactt
    30061 ctatttcata catgtaatca ttaatattta attttatttt ttccattttc tcctcctaca
    30121 gataaactaa tgttgtaata gaatattatt acaatcttat tttaatatta gtataagcta
    30181 ttccacttat gtccttccat tctattagtt acattagctc tcttacataa ttcttctgct
    30241 gcatgttgtg cattaagcaa cacttgttct tcactttcaa ttgtagttac ttttccattt
    30301 tcaagtatta catttccatc aactaaaaca ctctctacat tgtgcatact agctgagtat
    30361 accaaagttg atacaggatt gtgaagaggt attgattttg gagaaagcat tgagttaaat
    30421 attactaggt cagctttttt cccaatctcc aaagaaccta tttcatcttc cattctaaga
    30481 gttcttgctc cctcaattgt agccatttca agaactttct ctgcagaaat tgccagaggg
    30541 tcacaattat ttactttgtg ttgtaaagct gttaatttca taagctctac catatcttgt
    30601 gcgttattac ttgctgcacc gtcaagacct aaactcacat ttataccttt ttttaacatt
    30661 tctggcacag gtgcaacacc agaagcaaga tacatgttac ttgctacatt atgagaaact
    30721 tttatgtcat actttttaag catttccatg tcttcatcag ttatacatac acaatgtact
    30781 gctacaactt ctggacctac tataccccat ttttcaagta attttatatc tatttctcca
    30841 tgtatatcct ttgttgctgt tcttgcaaat tctgtttcag atatatgaac tgtaaaatat
    30901 gaatcatatt ctttaactat attccaaagc atcttaccca tttcttcaga tatagcccac
    30961 attgaagaag gagctacaca gatttttatt cttccatttt ctgaattatg atatttttcg
    31021 aatacccttc tcaaatcttt ttcaaccgtt tccacatctt ctataagctc tttgtgaata
    31081 cctaaatcta tacaacctct acctacaacc cctcttatac ctaaatcttt atatgccttt
    31141 actattccat ctgtaagtcc tggtctattg tgagtatgca tataatcaac cattgtagtt
    31201 ataccacttt ttaaaccttc catacatcca agcattgcag catcataagt atcttgttct
    31261 gttaagaatt ttgctgatgg aaacatcatt gtatttaacc actcatgaag tgccatatca
    31321 tcacctaaac cttttaataa cacttggaac aggtgattat gagtatttat aaagccaggg
    31381 aatattactt ttccattagc atctataact tttttagcat caagatactt aggctcaata
    31441 tcaactgtat ttcctatgtc caagattctg tcaccttgaa tagctattgc tccatcaaat
    31501 ataacatctc tgtctttatt aactgtaaca attattgcat tttttattag tatatcaatc
    31561 atcttaaatc cccctttgaa tactttcatt acaacatttt accatatggt tttctcatat
    31621 tatatctaat acatttatcc aatattttcc tcaagatttg aagtaacgtt ttcagcactt
    31681 ttacgtgact ttaatttaaa taatgtttga agtaatatag ctattattgc tccagaaact
    31741 atacttgacc ctccaaggac agttccaatt gtttctggga attggtctaa aacttgtgga
    31801 gcagttgtaa gacccatact tgttgctata gatacacctg ctataagatt gttttcttca
    31861 gtgaatccat ccatactcat aatagagaaa ccagacattg ctattgatga gaaaactact
    31921 aaagttgctc caccaacaac acaagatggt atagttgtca ttattgcacc caatgctgga
    31981 gatatccctg ctagtaataa tacaagtgcc cctagtgcta ttacaaatct acttgtaact
    32041 ttgttcatag atacaattac tgtattttgg ctaaatactc cagttggaag agctgcaaat
    32101 agtgatgaaa ttatagaagt tatagaattt cctaaaacaa ctgatgctaa ttcttcgtca
    32161 gttacctctc tatccattgc tcctactgta gctattgtac aggcacccat catatcagct
    32221 atacctatta tgtaaataat agtaaacatt actattaact ctggtctaaa ttctaatcca
    32281 aaagctgctg gtgttggtaa agatactata gctgctcctt gaacggctga gaaatcaacc
    32341 aatcctaaaa ctaaagatat agcataacct actaatattc ctattaatat tgaagaattt
    32401 tttactaaac ctttaccgta tttatttatc attattatta caaaagcaac tataactcct
    32461 actgtgaagt ttattgggct tccaaatgtt tgtgtgcctt ctcctccagc taaattcttt
    32521 atagctgttg cgaatagtcc aagtcccata catgctatta tagttccaga aactattgga
    32581 gtgaatatat gtctaatttt cttaactcca aatcctacaa agaatacgat taccccagca
    32641 gcaatctgtg ctccaaatag agctgctaaa ccatctttag ctgctactga aagacaagct
    32701 cctaaaaata cataactcat tcccatcatt acaggtaatc ttgaacctaa cttaaatcct
    32761 ttaaataaag gtattggata taactgtaaa aacgttgcta aacctgctgc taacatagaa
    32821 ccctgaatca acattgttgc ttgcccctgg ttaagtccta ccacgtttgc tattaatatc
    32881 gcaggtacca tatttcctac tatcattgct aacagatgtt gtaaggccaa aggtattgat
    32941 tcctttagtg gtggtatccc atcgacatca tattttgaag tattacgtgt tttcataaaa
    33001 taaatcctcc catacataaa tatcttgact aaatattttt ataattattt tctataaata
    33061 tttttatgac catgaattta ttgctcaacc gataaacaca gctaaactga gctattttta
    33121 taaaaaatta acaaatttct aaatattccc tccccgattt tcaacttaaa tgaacattaa
    33181 ttgcctggta tatatttatt tgttaaattt tttattaaaa tgaatagcta tcaaaaataa
    33241 tctaacaatc tcatactaaa taatttaaac aattctttta aattattata tcttaattag
    33301 tctcttccat aacagctctt tctttagcct catcctctag acttttattt ggtattatta
    33361 gatttaaaac gaatgcaacc aatgttgcaa ttactattgg agattctcca aatactaact
    33421 ttacaaatga aggaaatgcc tcttgggctg ctggtactga tgttattccc atgcctaagg
    33481 caattgccaa accaacaatg gtaatatttc ttgatgacaa ctcttctgta ataattaact
    33541 ttatacctgt cattgttatc atactaaata tagatattgt agctcctcct aaaacagaat
    33601 atggtatagt agtcattagt gcaccaaatt taggcacaaa ccccgacaat aacataaata
    33661 taccagctat tccaagcaca aatctactta ttactttgtt catagctacc atccccacgt
    33721 tttggctata tgatgatggt ggtaaacctc caaacaaagc tcctatcata gtacaaattc
    33781 cacttcctat tactccactt gataattcct tatctgtgat attcctatcc atgcctccca
    33841 ttgtagtagc tgataaatct ccaattgctt gaacagcatt gattatactt acaattacta
    33901 ctgagattat tacaggcata tcaaattcca tcccaaattc aagcggttta ggtatcgcaa
    33961 accaagttgc ctctctaata gggtcaaaat ttattatacc cagaactaaa gatacacaat
    34021 atccaactat aattcccaaa aatattgctg ccaattttgc atatcctttt gcaaattgac
    34081 taagacctat aactaccact aatgttatag ccgctactgc ccagttttgc atagaggcat
    34141 aagtaggact atttacacca cctgccatat aatttattgc tataggatac aaagataatc
    34201 caattgtaaa aaccactgtt cctgcaacta tattcggaaa aaattttctt atctttttta
    34261 tgaatatccc tattaatact gtagccactc cccctattaa ttgtgcaccc aaaatgcttg
    34321 ctaatccata atttcctccg actgctacaa gtgttggtac ataagtaaaa ccaactccaa
    34381 aaattatagg caatcttgaa ccaatatttc ctattggata tagttgtata agtgttgata
    34441 taccagctat tattaatgca tattgcacta aaagtgttat ttgtgtaggg ctaacaccca
    34501 cagctcctcc tacgactata ggtactgtaa cagttccaac tatcattgct agtatatgtt
    34561 gcattgatag tggcaaacac tttaaaattg gtggccttcc atcaatatca aacatagaaa
    34621 cattcttttg atatttactc aaggttatca ctcccaacta ttttttaatg acagttatta
    34681 ttatctcaca caacatcctt tcttttttta ttttgtcatc tcaacttaat atgaagcaat
    34741 tataatgcca attttttaac ataattgttt tacatatata atttttatta tatttgttag
    34801 tatttgataa tttattaaag catttatttt tttaaattct tttaaatttt ttttattttt
    34861 ggataataaa atgctattac acaaaaaaac acttagaaaa tagttttcca agtgtttttt
    34921 atcaatttta taatttcaaa ttttagaatt gagaataaaa agcctaatta ttatacatct
    34981 atttttctgt acaatgtagc tagtgatatt ccaagttttt tggcagctag ttttttagac
    35041 ttagtatcat ttccgtaaaa ctttaacact ttctttatat aggctctttc aaactcttca
    35101 agtgtaagta tgtcttgttc catacttatc tcatagtcac tttcctcaag taactttata
    35161 tttatattat ttaacttaaa atattcaagt atctttctat ttattattcc tttatgtatt
    35221 attccatctt cctcaagaag gtttaatgcc agttctatag tattttccaa ctctctaata
    35281 tttcctggcc aaggatactt aagcaacatt tgttccacat ctggctctat atggtacacg
    35341 tttttcttca tctttcttga atatttgtct ataaaattgt ttattaatat ttgtatatcg
    35401 tctcctcttt ctctaagtgg aggcacttct aaaggtatta cattcaatct atagtataag
    35461 tcttctctaa atttattttc cttaaccaac tcaaataaat ctctattagt agctgatatg
    35521 attctaacat ctatatcaat tagttcattt gaacctattc tcgtaaactt cttttcctgt
    35581 aataccctca ataactttga ttgtagttga attggcatat ctcctatctc atctaaaaat
    35641 acaacccctc cattggccaa ttcaaactta ccaattttac cttttgaatc tgctccacta
    35701 aaagctcctt ttgtatatcc aaaaagttca ctttctagta aaggttctgg tatagcagca
    35761 cagtttatag caacgaatgt tttattccct ctgtttcctg cgagatgaat ggctcttgct
    35821 attaattctt ttccagtgcc actttctcca gttatagcta cagtagaatc actatttcca
    35881 attttacaaa ttctattctt aagagcacgc attacatcag actctccaat tatggagtct
    35941 actgttgttg ttccccaaat attatatact tccattccac catacattac tgaatcactg
    36001 tgtttgtcca taaaatatca actccaaata agtattctat ataataatca ttcacattat
    36061 ctatttaatt atatcataac agaaaagctt agttataatt taataatatt attttaaaac
    36121 aaaacttaat aaaaagtata tctacttagt tttaatttga tagatatact ttcttcattt
    36181 tacaaaaatc ctctattaaa taagcaatta caatgccata ttttatatgg aaataatttt
    36241 taaaattttt aatttaagtt cttattaaat tttttatact actcgtaatt tttataccta
    36301 tataaaatta cttttataaa ttttaaaatt cttattttta aaatttataa ttaaaaatta
    36361 tcttttttaa atcatttttt gtgtttttta tatcatctaa cctcacagtt tttgcttcta
    36421 taaacttacc cttaaatgat tctgataatt tccaggaact ataattctta tctttttgaa
    36481 tacaaggata taataatata catctttttg cattttcata tgctgttata tatgcataca
    36541 tctggtatat atcacttgac ctataaaaaa catttgaatc tacttcaata gctttccatt
    36601 tagtgtcaat tataatttca tattcatttt ttaagtcata taaaactata tccggtctta
    36661 aattaaagtt tttcttacca gtttgttcat ttttcaaaag aaatttactc ttatcttgta
    36721 tatatgtttc tctaaatgaa ttgtcccata tacttttgat taaaattcct atatattctt
    36781 catacaaagt atttatttca aataatatag aaaatgcctc ttgattattt tgactattat
    36841 ccatagacaa atttaaaagt agaagtctag ctagtaaata acaatcttta aatctatcat
    36901 tgtttttata aaatttataa tccaacagtt tttttctatc tatataaatt aaatctacat
    36961 tttgaaaata gcttaaaatt tttttaatct tgccttgaat tgaattgtca tttattctac
    37021 ataaaataga tatacatgct tttttaagaa cttgattcaa gaaattattt tcactatact
    37081 catcatattc acatcttatt ttcattggag aaatgccttt ttcttttgca tatgtactta
    37141 ataatatttt acccctcata acatttaagt tctctatttt atttatatat tcaaaataaa
    37201 tacctttttt catctgtgtt tgcatactct caatgaaata cataacaaaa aaatttaaga
    37261 gattataatt tttcaaactc aatcttattt tttcattcat tgtaattgga attttattac
    37321 atatagaaag catctgtaat agtatctctc tatcttttac aagattatca cttaatgaca
    37381 atttaggaag tatttcaagt attacatttt caaaacatat gatgcctaca tagtttataa
    37441 atctaagttt tttgtattta atatctatta tattactttt taatacatca ttattgttct
    37501 ctagatgctt aagcaatttt tcatattcaa tttctgtaag ctcattttca ccattaccta
    37561 cccttatcca ttcataggtt tccttaacat atatattttt actcatatat attttttagc
    37621 tcctcactag atatgttttg ttttatacaa tagttaactt tactctccat tattgaggca
    37681 ttattatttt taaataactc agaagctata agtttttctt tataaacaat gtatttatct
    37741 ttttcatttc ttccaattcc tcctaaaatc aaacctactt tttctgaatc ataataaaaa
    37801 tactcttgaa gaagtggtat tattttactt ctaaatacta ctactatatc attaatattt
    37861 tctacagcaa gtagataagc ttgtccaata acatggtctc tatcatataa aaactctatc
    37921 cttttattga ttgtatatag catttttcta atatctatac catctacaat agacaataaa
    37981 tcataatctg gcataatttc ttcaaaatta aaccttcttc ttaaagctat atctaaaagt
    38041 gctattgatt tatctgatgt gttcatagtt ccaactatat acaaatttgg aggtagagaa
    38101 aatttttcct ttgaatatgg tagtttgaca atagtttgat ttgatttagt aagtctttta
    38161 tcatcttcca ataatgttat tagctcacca aatattttag atacattccc tctattaatt
    38221 tcatctatta ttaaaacata gttttctgat tcttcaaaat taaaactctc actatattct
    38281 atattttcta atactaattt ctttttcctg tcttttatag tttctaaagt caagctatct
    38341 ttttccaact caaagctcat ctttttttca aatttcaatg cattataaca tgcttctata
    38401 gatatatcct ttaatatccc atcttctggc ttaaaattgc cttcaccatc agacttaaga
    38461 ccctctataa attcctcata tccatatgat tgatgaaatg tacaaaattc tacattgttt
    38521 ttataatcta agtaacctgt atagtatctg tttcttagac tggtttcact tactagattg
    38581 taaaccatct gttttgtatt gtatgtttta ccagttcctg gtggtccata aagtatagta
    38641 tttaatggca ttttattagt aaatcttttt acatactttt caactatact attattttca
    38701 aatataaccc atgcatttcc gtctatattc tccttttcat actctatcca tctaacagga
    38761 aaaaaatatc caccctccaa agcacttact ttctctttat cgaacccttc cataacttga
    38821 catacgccaa atagactctt cattgtatgg tcattttcac aaattacttt ctcgctatta
    38881 tacaataaaa tataatcatc tgtctttata ttttttagac tttctaattg ttctagatta
    38941 atgggctgaa taaataattc ttcatcatct acacacttat ctacattttt ataataatag
    39001 ttttttaaat accatttatt attttcactt tcttctattc tttttctcaa taatttctta
    39061 tcttgtgact taataatttc taaatatgag ctaatatcat tattatttaa tttataaaat
    39121 tcacttgtat atactttaca atttgaaact gtatcaaaat tatgcatcca ttttactggt
    39181 agtgtatgcc ctaaaatatg acttaattca tatccatttt caaaatcttc ttcaactatg
    39241 ccaatagaca cattacattt aactttttct tctatatttt gatatgcttt atataaaaaa
    39301 taatctcctt ttttaatcaa cataaacttt tttataaaat ctttatcatt acaattctca
    39361 ttaatatact tttctgattt tttccccata ctgaatactt tttttaaatt tatttttata
    39421 tcaaatccaa gtgcaattat gctttcttct ctaaaaatct gtggtgtgtc tgtttcctga
    39481 taaaaaaatt cttccattaa ccaatactct gtacctctta tattttcaga catatacact
    39541 ctccttaata tctaaaatat actaattata caataagcct actctaatat ttccatttaa
    39601 attttccttt atatataaag aaaatattac ttcatagctt tcttctacct tgctctgaat
    39661 attacttatt aaatcattca attccattat agaaaattct ggacttcctt caacaaatac
    39721 aattcctttc ttacttataa attcctcacc aatatattcc atcctgtcaa ataaaatgtc
    39781 agctatctcg ctatatgact ttgtatcttc aaactcttca aaagaatact taattccttt
    39841 atctcctaca atagcttctt ttaaatcagt aatatctata tttatcatgc aagaatcaga
    39901 aatagactct accatgatat tcattaaatc aacaaattta aatatactat cattattgat
    39961 tttaaactct ctcccaagct ctaaatcttc tttattttcc ttctctgaac aatccattcc
    40021 tatagataga actcttcttt cgtttgacat atatgaaaca gcttttataa tatctctaat
    40081 atgtttatct tcagatgaat atatcaaaaa taatatatct acaccatcta aaagacttct
    40141 aacatattct ttttcaatct cttgatttat gtttattttt tctatatcca tatttgcttt
    40201 tattttttct tctacttcat ttattatatt aataccttca gctccaatac caattatttt
    40261 agcattctta ttaaaatttt ccattataac gtatatctcc ttaataatta tttaatttca
    40321 acatttctaa atattatacc atattttctt cataaaaata tcttaactca ttggccttat
    40381 cataaagtag cttattcaaa aattttggct ctataacctt agcattattt ccaataaaaa
    40441 ataaaatcga agcataacaa tctatatctt caacctttat gaatgtacta attattccac
    40501 taccatcttc atttagctcc atatctaaat tccaagaact gtcctttatt ttagaaacac
    40561 cttctttagt taataataca tttagataaa taatttcacc aaatttttta gtagttgaac
    40621 tatttccata taaattgtta tatacttcat gtaaccattc ttccaagttt atatgtattt
    40681 ttttactttc tcctgttctt tttatatcaa ttatattatc tatatgaact aatattattt
    40741 tatcactttt acaatcatat gctggtgaaa accatgctcc cttatttaaa tatataccta
    40801 tagggcatac gtttttttcc aaaatctgat taccacactt atacttaata tttaaaatta
    40861 gagattctga agaagctcta aaaaactcag ttacattact actcttaaaa tctccatcat
    40921 tagtatcatt agctacaaag ccaatgtatc ttttaatatt ttctatacct acttttatac
    40981 tgcttttacg ttcataactt acttttctca ttatagaatt aatttctatt tccattaact
    41041 tataattata aatctgaagt gacttaagtg caaatagtat gatcataact tctttttctg
    41101 taaatataac aggaggtata tagctattat ttagcaccct ataacctcca tttctacctt
    41161 gttctgcttg aattggaagt cccattttat ttaattcttt taaatatcgt tgtattgttt
    41221 tggctgaaag attaaattcc tctgacaact cttttattgt aaacttttgc ttatcattaa
    41281 tatatatcca aacatcagtc aatcttttta ccttcgacaa ataaacacct cttttcacta
    41341 ataatactct caattaatta aattactata cactatttaa aatttaatat taatgacatt
    41401 tttatatttt ttcattaaaa aacagaaaaa tggtactcct acaattgtta ctactacaaa
    41461 ttctccaaaa cctacctgta tcatagatag aattaatgga agcccaaaga atacatttaa
    41521 cattagacca accacaatcg aatttataac agttggccat aaagaagcta taactaaagt
    41581 acttttattc tgtttaccta actttctagt aatataaatc atacttgcac ttataaatgt
    41641 ggctaatgtt ccaaaaatta tatcaggtac accatatggt cctattacat ttgctaaaaa
    41701 acaacctaat gtaagaccta ctatatatcc tttatctaaa aatgccaaaa gcatcataat
    41761 ctctgctacc ctaaattgta ttggtccata acttataaat cccaatgata atgttaaaac
    41821 tgcatagatt gctgtaattg ctgcagttag tgctatatta atactatttt ttctcatatc
    41881 tgtctcctag taaaagtttt atttttaaaa aaattaataa cataacttta ttttatacaa
    41941 aatctataaa cttaaacagt aattttataa aaacaaatta ttttagcgaa ctattttccc
    42001 aattcatttt atattataca atataataca tacaaattca attttatata tatagaatat
    42061 atgatattaa aattatatac aaactaaaga taaattttct attgttaatt aaaaacagca
    42121 aaaaagagcc ttaaaattag gctctaataa tttattttaa aatcagtgaa ctctactacc
    42181 atcttttaat ttagataata tcatccaagt acctatacaa tcaatttcca gttgtttctc
    42241 tatttcatca tataacattt cttgatatga tgtacttaaa acaacatttt caaccaattt
    42301 agaaatttcc tcttctgcaa aatcaatttc tatttgattt tgtttttctt taaaaaatac
    42361 ccttactttt ctctgactta ttgaacgacc ctcaaagctg actaaacatt ctaagatgct
    42421 cttatctcct ctaaaattat ttactgctct catattattt agattaccag ccaaaacatc
    42481 atccccttat ttaattttgt attttataag taaaattcat aatattataa taactactta
    42541 ttaaatatct ttcaacaagt atgacataac tggttgttta acatgtaaaa ctagtctaaa
    42601 ttttcataaa caattattta ttcatttcca taaaaacttt ttcaggtgta atagggagtg
    42661 tatttattct tacaccaatt ccattaaaca cagcttcttg tattgctggt aaaggtgtat
    42721 ttataacaac ttctccaaca gatttagcac caaatggtcc agttggttca taagtttcaa
    42781 caaaatctac tttaacattt ccaatatcac atctagctgg aatcttgtat tgcataaatg
    42841 tatttgtgtc catgcttcct ttttctgtgt atctaacttc ttcaaataat gccattccaa
    42901 tcccttgaac aattccacct tcaacttgta tcttagctag atttttattt ataaccgttc
    42961 cacaatctac tacagctaca taatttacta aatcaacttt tccagtttct gtgtcaattt
    43021 cagtttctgc aaaacctgct ataaaaggtg gaggagatac tgggctacca tgagaagcaa
    43081 gacctattaa ttgattagta tctggaccaa ttgtagaatc aactgctata tcgaataata
    43141 aagtgctacc ttttttacta gttaatttta taccatcaaa ttctacttca tccttctcaa
    43201 cacctagttt agttgctcca gcagaaatta ttttttctct taagtcttga gctgccttaa
    43261 ctactgccat acctgttaca taagtagtac ttgaagcata tgaacctggg tcatatggaa
    43321 ctaagtcagt atcagctgat ataactgtta tattttcaat gcttgtatca agaacctcag
    43381 cagccatttg agctaaaatc gtatcacttc ctgtacccat atcagtagaa cctatcataa
    43441 gagtataatc tccacagtca ttcaatttta tttcagctga agacttatca agaccttgta
    43501 taccagaacc ttgcatagta attgccatac ccacacttct aatttttcca ttatcaagat
    43561 gtttacaagg atatttttca ttccatccaa taagttcttt gcctttattt atacatttta
    43621 ttaaatcgac actatttaaa gttttaccat atgcaaatgt agtttcacct tctgttacca
    43681 cattttttaa ccttaaatct gttgggtcca tttttaattt attagcaagc atatttatag
    43741 ttgattcaac agcaaaacat ccttgtgatg ctccataccc tctaagtgct cctgctggca
    43801 tcttattagt atataccaca tctgcaataa atcttgttgc ttcaacttta ttatacattg
    43861 gtaaagtttt ttctccaacc aaaccaatag ttgtagaagc atgctctcca tatgctcctg
    43921 tatcagaaag tgcttttata tctattgcct ttattatgcc atcatttgta gcacctagtc
    43981 taacttttaa tctcattgca tgtctacttg ttgaacaatt aaaagtttct tttctatcat
    44041 aaattatttt agctggtttc cctgttttta aagtaacaat tgcagaaaaa atctcaacac
    44101 atgcagtttg tttaccacca aatccgccac caattctagg ttttataacc ctaattttgc
    44161 tagctggtat ttctagtgca cgagataaat gtctttttac atgaaatggt atttgagttg
    44221 aacttactac aaccaatctt cccatatggt ctaaataatt gtatgcccta tacgtctcca
    44281 tcattgcatg tgcttgagct tgagtataat aagtttcttc aatcactaca tcacaattac
    44341 ttaatacttt ttctacatca ccttttgtat aatcatgatg ggatactata tttttttctc
    44401 tttgcatacc tatatcaaag ttacaatgtc tatcttcatc atgtaccata gttttatttc
    44461 ctattgcctc ttcaaaatcc aaaacaggtg taagtacttc atactttact ttgataagat
    44521 tcattgcttt aattgcagtt ttttcatcta tagctgccac tatagctact tcgtcaccta
    44581 catatcttac aacatcttca agaattaatc tatcatatgg agatggctct ggatatgttt
    44641 gaccagcaag tgtaaatcga gattttggta catctttata tgttaaaaca cattcaacac
    44701 catcaaccat ttctgccttt gatgtatcta tatcttttat ttttgcataa gcgtgaggac
    44761 ttctaagtat ctttaccacc aaagcatctt ttgctgataa atcatctgta tatacaggct
    44821 ttcctgttgt gatactcatt ccatctattt tcttgattcc ttttccaact atattcatgt
    44881 tctattttac ctccagataa gttttgatag ctcttaactg tcccatatac cctgtacatc
    44941 tacatagatt tcctgtaaga taatgcttta tttcatcatc tgtaggattt tcaagctcat
    45001 ccttcattgc aagtacagta agtataaagc caggagaaca gaaaccacat tgctcagctc
    45061 cttcttttac caaaacttca ctaaattctt taacttcatt ttctaaacct tcaattgtag
    45121 ttatttcttt atctaaagct ctcaatgtca gtgttgcaca agataatgta ggtttcttgt
    45181 caattaaaac tgtacataaa ccacaacaac ctgtgtcaca acctcttttc acacttaaat
    45241 taccaacttt tcttaaagta tcaaccagat attcttctgg ttctatatca acactttttt
    45301 tcttcccatt tatattaatc tttactaaca ttaaataacc tccattatag ctctttttaa
    45361 aagtacttta ctcatagctt ttctatactc cctagatgct ctcatgttag aaccaaaagt
    45421 tagttcttct gatgctattt ctactgcttt atctatatta atttcattga tttcattgtt
    45481 agatagaaat tcactagctt gttttgcaat cgtagctttc tgcggtcttg ctcctacaca
    45541 taacttaaat tgttccatat gttttgatac agatacattt agaattggat aatcactctt
    45601 tgcatttcta attgatttat aagaagcatt cttatttgtc ttctttatgt atatcttaat
    45661 aagtaaatct ttctcataat ctctatttag aaactcttca agactaattc tcccaatatt
    45721 atataattct acttccgtat ctaatgaaag taatgctact atcaagtcag aaaaaccata
    45781 tttagaaaat actgttgcac caactgttac tacatttcta aactgaactc ctattatatt
    45841 tttaactgaa tcttctatta ttcttccaaa attatttttt attatggaac ttgtttctaa
    45901 tgttctaaaa gtagtcatag aaccaatctc aacgtaatct tcatactctt ttatataatc
    45961 taaatttaat ttagataatt ctattcctgt tcctattctt tttttcccca ttcttaaaaa
    46021 agcacttcca ccaattactt ggttagtttt tcttttattt aaaattgagt acgcttcttc
    46081 tactgtatct ggctgtacaa tatccataac cgtaaacata aatttcctcc cttatttgct
    46141 attcttattt taaatacaac taattatatc atagcttcaa caaattttga taataaatat
    46201 gtctaatatg taaattctgt aaattactta tacataaaaa aatgactatt tcaataatca
    46261 tcattagaca atattaaaat agccattaac aggtactatt ttaaagcaaa actttaaaaa
    46321 gttgatactt tttcacttat atttatcact tcttcttcta ataatccaag ttttttagct
    46381 actaattttg tagtacttcc ttgtattact aatgtaatta gtatagtcat gaatactaca
    46441 gatgaaatca cttcgtatcc aggaactttc attgctgaaa taataccaca aagtgctgct
    46501 ggtattacgc ctgtttccct tacccacatc ataaataata tttcactttt actccatttt
    46561 gcttccctgt ctacaagtgt acaaactaaa acgcaaagtg gtcttgctat aaacattaat
    46621 actaatactg taattacaga tggcataaaa tatttactta actgagccaa attaacttgg
    46681 ctacccaata ttataaatat tgccatacga caaatagtac ctaaagtttc agcaacataa
    46741 aaatctgcat cataagattt ttgacttaac caaattttaa agtttttctt gttaccagtt
    46801 attataccta caataaagca agacatatat ccacttccac ctaattttgt agataattca
    46861 tatgcaacta caactgaaat aacagatatt attggtgcaa aatctttaaa tattccataa
    46921 ggtttatcat taactaattt caaaagcagt attcctgtaa ttaaaccaac taaaactccg
    46981 acaataacca ttgtccccag ttcataaata ttttcaccta atgaaaattt atttgacaaa
    47041 attacagcca acactgctga tgttagtata gctcctgttg catcattaaa agctgattca
    47101 cttattacag tttgttttac cctatccttt atctttacct gattaaatat aggtacaaga
    47161 gtggctgggt ctgttgatgc tattatagtt cctgctagta aagcagtcat tgcacttatc
    47221 ccaaaagtaa atcctattac ttgttgcatt ataaaagcag atatcacaac tcctaaagta
    47281 gctaataaga atacagatat cttcacattt ctcaatactt ttaaacttat ttcttttcca
    47341 cctaaatata aaataaatgc agaaccaaat gtaagtatta gttgattttc tatttgaaat
    47401 ccacgaatat ctataaattt taaaaatgat ggtcctatta aaatacctac aagtaaatat
    47461 aacactacat ctggaacctt tattatttca ctaagcttac tacaaattat tccagttata
    47521 cttacaatag caaaaattat caataaatta ttgctggcaa ttgtgtgtat agatgcttcc
    47581 atgtccgtct ctcctcccga tttgcataca ttatgcaata tacttattgt tttactatat
    47641 aattatagca cacaaataaa tgttatcaat catttttttt aggacatgca atttagcttt
    47701 catttttgac aattaaataa cgcttatata attttgctat tttttgctag ttattaaaag
    47761 gttgattttg tcaagtttat agtatatata tattaatatt ttttatatcc atatcttttt
    47821 agatattttt cgactttttc ctccattaaa ataagtttaa atttaacaat aaaacatttc
    47881 attatatata ttttttaaaa tgtaccattt tcaacatttt cattaacttg gtctattcat
    47941 ttttttctta tctattctat ctccaagcat attccctata tttttactta catgtaattc
    48001 ttgagctatt tcaagtttat tatcattgct ttgttttatc ttagaaatct cactttgttt
    48061 ttcatttttt ttatcttgtt tcatagtttc tcctttcaaa acaatatcac tctttctgtt
    48121 tattacttat tatttcaaat ttctataatt ttaatcaaaa aagggaaata tctcaatata
    48181 atatagctta ctcaacacca tatttatata tagaatttcc ctaattattt tattaattta
    48241 atttttcaat aaccttatct aaattagaat ttactttatc ttcctttttc caagaattta
    48301 atgtataatg cgttccaaat gtaaataaac ctgaaactat taatataaaa tagtatacaa
    48361 acccactata taagagtacc gagtacccca ataattcttt tggaattata ttggagaaca
    48421 tagtaaaaaa tgtaacctca ttagctccaa catttcctgg tgttggaatt ggtgatatag
    48481 ccatatataa aaagacctgt aatgtcatta tatgtacata tgaaactcct cttaaatttg
    48541 aggctttata cacacaataa actatactga aatatgcgat taattgtaac acagtaagta
    48601 atatacttaa aactaagatt cttacatttt taataaatat ttttatagaa taattataat
    48661 catcaatata atgatttatt ctatcacgtt ttgaatctaa aaatttaaat gttttaaatt
    48721 tagataaaaa attaatcaaa acttctgcta tcatttttac ttgttttgga ctaaatacta
    48781 ttagtagtcc acctaacaac atacttacat tcataatcat tccaaaagtt atcaagactt
    48841 tcacagaatg tacttgctcc atcagtaatg acttatttag caaaattaaa attccacaaa
    48901 atacagtaac tgtactttga aatactacag ttttattagt aactatagcc actgatttac
    48961 taaggcttac atcatatttt gtaagtgcat atatttgcat tggttgactc ccagatgcaa
    49021 atggagtaac taagttatag taaaatccca ttgtagccat tttaatacca ataaatttta
    49081 cttttgtttt ttgaactgca tttattatca aatgagttac aatagattca attatcatat
    49141 atactataat tgtcaatatg ccaagaaata tataagtctt atttactagc cttataattt
    49201 taggtattag ttttatatct aaagtagtta atactaaata agtagtaata catatcaaaa
    49261 ataataaaaa tccatattga ataaaatctt tttctctttt ggataatttt ctcatttatt
    49321 ttctcctaaa ttttttcata tcactataca tagtatacta cttaacctat tatttgcaag
    49381 actaaaaaag ataagtcttt atttgacata aatacactta taaattttta aatattttta
    49441 ctcctttagt agaaataatt ctccatatca taaaatctaa tatcaaagta agtatacttg
    49501 ccaaaataat atatatattt aaaaacgaaa ttccaagtaa tacatatata cctccaagta
    49561 taattacata agctaatgat actaacattg taactatcat acttgcactt ctttttacta
    49621 cagccacctc atttttccaa tcaaggtttg ggtataataa atttgataat aatcccatca
    49681 atgctacaaa cattgaaaaa cttccaatca aacagattga tacaataata aactgaattt
    49741 caaagtctaa tcttatagat actaatatta gacataaaat agatagtggt gcattcaata
    49801 aaaaattcat caatattttt gaccagaata tttctctttc atctattgga gaagatttca
    49861 gtatccataa gttttttcct tcaagagaaa ttgaacagta tgttgtacaa ttcattacta
    49921 ttataaagaa gaatactccc aataattgta tttttataag attaaaatct atattcaatt
    49981 tcaataactc acccacttta tctgctccaa ataataatat taaaattgta cctactatta
    50041 gaaacaacaa acctgcagat gaatttaaaa agtatataaa cgaagaagta tatctcttaa
    50101 attctttttt taataaagct tttgaaggtc ttgaagtttt ttgaccctta aattcataat
    50161 tttttgactt atatccttca ctcatcttag catttatatc tttaaatttt tttgcaaaca
    50221 gagttacaaa cataaaaaat ggtattattg agatggctat aaatgctaaa aatgaaacta
    50281 tacttcctgt tttaagagca tcaacaaaat aatatatagg aggatatact tttctaattg
    50341 tctctgaaat agacacacta ttctttagca tttcaactga catagaatta agtcttgaca
    50401 taagtagggt ataaagcaac atcaatataa tgctacctat gattaatact aaatttttgt
    50461 attttattct tgatgatatc tgccctataa atagaaaaat tattgatgaa gcaactattg
    50521 gtaataatgg taaagctaaa aatagcaata tcaaataagg gaaataagtt atacttacat
    50581 cagaatttaa aaagtaaacc actgcaggta taatcataca tattgaagaa aataaatagt
    50641 ttgctccaac caacattaat atcttacttg ctagtacagt agattctttt ataggtaaac
    50701 tagtcaaaag gtctaaatct tttgcttgaa atagatatga tgacgtttta tataatgatg
    50761 taacaatagt tgttaatgtt gataatccaa aaccaaatat cagtagcatt tccagttgat
    50821 ttatttgctt taagatatca actaaagaga gacttaagct cgttacataa aaaattaata
    50881 gacccgctat tataacaact gaaagcatca ttcccattat tttttgtttt tctctaccat
    50941 cagctttttt taacgcattt aatttaaatt catttattat attagttttt attaatatac
    51001 ttagattgct catattttat cattcctcac tttagacact atattgtata aaaaacattt
    51061 tatttctcta ttaattccat gaaaatactt tcaagtgaat tacttccctt aacttcttct
    51121 gtagttccat aagcaattat atttccatct tttattatgg caatcttatc acaaattttt
    51181 tcagcaactt ctaaaacgtg tgttgagaaa aatatacaac cacctttgtc acaaaactcc
    51241 ctcataattt ccttcaatat aaaggaagct tttgggtcaa gacctacaaa aggttcatca
    51301 agaattaaga tttttgggct gtgtatcaaa gccgaaatta tagctaattt ttgtttcata
    51361 ccatgcgaat atgaagatat taaatctcct aatgctttat tgagttcaaa cttatttgaa
    51421 taatatttta ttaactcttc tcttttatct ttggcaactt caaatatgtc agctataaaa
    51481 ttaaggtatt gtataccagt taatgactcg tataaatctg gattatcagg tatatatgcc
    51541 atttcctttt tacattcaac aggctgtttt tttatagatt tagaatttat tagtacctct
    51601 ccctcttcaa aatcgtgtat tccaacaatt gctttaatag tagtagtttt acctgctcca
    51661 ttatgtccta taaacccaaa aagctctcca tcatttacat caaatgagac actacttact
    51721 acttttttat ttttatatga tttagataca ttgattactt ttaacataat ttccctccat
    51781 attatagttt tgatatttgt tatatataat atataacaaa tatcaaacaa ttacaacttt
    51841 tatttgttta ttttagaaat ctataaaatg caaaggtatc agaaatataa aggtataaat
    51901 ataattgata tttactttca aattacacat aattataaaa gaatatatag ttcgatttga
    51961 ataaacaatg tataataaaa aatagttgac tataattatt aaaatataag gagcaaaata
    52021 tgaatacatt tgaacaacta aaaataagtt ccactctaat agatggactc aaaaaacaag
    52081 acataaattc tccaacagaa gttcagtcac ttgttatagg aaatataatt caaaataagg
    52141 atttattgat taattcacag actggaacag gaaaaacact agcgtacctt ttacctatat
    52201 ttgaaaaaat tgatacatca aaaagagaaa cacaagctct tatacttgca cctactcatg
    52261 aattagtaat gcagattaca aaccaggttg aattattggc taaaaatgca gaactctccg
    52321 ttacttcttt agctttaatt ggggaggtca atatacaaaa acaaataaaa aatataaaag
    52381 cagtaaaacc acacatagta attggctctt gtggaagagt tttagacttg ataaaacaaa
    52441 agaaactaaa atcacataat ataaaaacta ttgtcttaga tgaagtggac aatctattga
    52501 atggaaaaaa tataacctgt atagaagaca taataagaac aacgttaaga gatagacaaa
    52561 ttataggatg ctctgcaagt cttactgata gcactataaa aatttgtgat aaacttatga
    52621 aggagtttga aataataaaa acaaaggaaa aatcacaaat aaatcctaac atcaatcact
    52681 catatttatt aggtgagata agggataaat ttacttttct tagaaaggca ttagcagcta
    52741 caaatccaaa aaaagctatt gtatttgtaa ataatgaaaa aaatatagaa gtcctagtat
    52801 caaaactaaa ttatcataat tacaaagcaa taggaatttt tggaaatatg gaaaaagaag
    52861 atagaaagaa tgcaataaat aaatttaaac ttggtaaagc aaagatttta attacaactg
    52921 atttatctgc tcgtggacta gatattgtgg atgtaagtca tgtttttaac ttggattttc
    52981 caaaaagtaa aaatgaatac ctgcatagat gtggtcgaac tgctagagga aatcgaagtg
    53041 gtaacacaat ctcaataata acaaaaaaag aattagatat tataaaagat ttgcaaaaag
    53101 agttcaatat agtaattaca cctaaaactt tacaaaatgg agaactaata gacattatta
    53161 aataatacaa caaatacaaa agagctgtag tttatcatca caattgataa taaattacag
    53221 ccctttattt tatattaaat taaaatttta aataatacct attatagtag ccaaagtttt
    53281 attataaata atattgccag aacaatcatt actacagaaa catgtttttt gtcttctgcc
    53341 tttttagctc caaatatatt ataaaatata tttacgaaaa cataagttaa tatacctaaa
    53401 gttaaaccat cacctatact atatgttaat gccatacaag caatagtaac aaaagctgga
    53461 acaccttcag ttatattatc aaactctata tccttaactg taccaagcat taaatatcca
    53521 acatatatta aagctggtgc tgtagcacat gatggaattg ctataaatac aggagagaaa
    53581 aacattgcag ctaagaataa aattccaact gttattgctg tccatccagt tcttccacct
    53641 gcgataactc ctgttgaact ctcaacataa gttgtaactg tagatactcc aagtcctgca
    53701 ccaactgtag ttgcaaccgc atctgtaagt aaggctctac ctacattagg aacattccct
    53761 ttttcatcta acatgtttgc tttagaacaa acaccaacta atgtacctac tgtatcaaaa
    53821 aaatcaacaa ataaaaatgt acaaactact actaaaaaac cacctatatt tgttggatgt
    53881 agtacatatc ctaaatctat tttacctgct attggtgcta aactttcgaa tttaaataat
    53941 ccaccaggta aatatatacc taatttttgt gcatactctg gatttataaa agcaaatgcc
    54001 caagcaagta atgaactcac tactattcca aaaagtatag aacctttaac tcttttttta
    54061 tctaatacag caataattat taatcctaca caagttatta ttactgctgg tgtaaatcta
    54121 cccattttga taagagtggc ttggtctcca ataacaattc cactgttaac tagacctata
    54181 agtgcaataa atattcctat accacctgta acagctaatt tcatattttt tggtatcgca
    54241 tttacaacag cctcacgaac tccacttact gataatacta taaaaataat accttctaca
    54301 aatactgctg taagagctac ttcccaagga acacccattt gtaaaactac tgtatatgca
    54361 aaaaatgcat taagacccat acctgatgct aaagcaaaag gaaggttagc aactacaccc
    54421 attaaaatac atccaaatgc tgctgctaaa caagtacctg taacaagtgc acctgcaggc
    54481 atgcctgtct cagataaaat atttggattt acagctatta tataagccat agttaaaaaa
    54541 gtagttactc ctgcaattat ttccttcttc atgtcgacat ttttattagt caaaattgga
    54601 aaaagtttct gcatagtact actgtttgtt gtttgcataa caacacctcc tattaaattt
    54661 tacaaaaaaa cgacacagta gttgataagc tgagccgtat ccttcataat tcagttaatt
    54721 aaatatttaa ttaactaaat aatagtatac atagtcagaa tatttacggt attccggtag
    54781 aaacttatga cccatattgt caaaattata tgttatacag tacaaaacat gaatttttct
    54841 ttacgaatat tattttaatt tatataatta attttgtcaa tatatacgta tatattgtat
    54901 tgattttgta ttaatattcg attatattaa atattgattt attaaattca aattataatt
    54961 atattcttta cattttaaaa aaatatatga tattttgata caatttattt atagtttgga
    55021 tataaagttt atgttaagat tatactataa taaattaata atttttttat ttggaggaat
    55081 aaggtgaaag atttaactac aggtcatgag ggaaagtcca tattcttttt tgccatgcct
    55141 atgcttattg gtagtttatt tcaacaacta tacaatacag ctgacagtat aatagttggt
    55201 agatttattg gaaaagaagc aatggcggca gtctctggag ctaaccctat aatgttttta
    55261 ttggtggcag cgcttatggg tgttagcctt ggattttcta ttttagtgtc acaattttat
    55321 ggctcaggag atttaaaaaa ggtaaaagct actattgata ctacatatat acttttattt
    55381 attggttcta tattaataag tattcttgga atagtatttg gtggccccat gcttaagctt
    55441 atgaatacac cagaatccgt ttttgctcaa tcaaaattgt atcttactat aatatttagt
    55501 ggaatattat tttctgctgg atataattca gtaagtgcaa tacttagagg acttggagat
    55561 tcagtaactc cactttattt tctgataata gccacaattc taaatatagt tttagactta
    55621 acttttattg tagtgctaag aatgggtgtt gagggcgttg cacttgccac tataatggct
    55681 caggcagtat catttataat aagtataatt tatttaaata aaaaacatga agtgcttaaa
    55741 tttaaaatca aaggaattgt atatgataac aaaatattta aagatggact tagattagga
    55801 cttccaagtg gagttcaaca aatgttgttt tcaattggaa atatggctct tcaattttta
    55861 gttaatagtt atggtacatc tgctatggca gcttttggtg ctggtcttag gatagaaaat
    55921 tttataagct tacctattat gaatcttggt tctgctgttt ctacttttgt tgctcaaaac
    55981 ataggtgctg gagaaaatga aagagttaaa aaaggcattc gagaatctat aaaaatgacc
    56041 ttagttttag cagttacagt tattgcttta attttgctat ttagggaaaa tctaattgct
    56101 ctattcaata ctgataaaga tgtcattaaa attggctctt cttacttatt tataatagga
    56161 ccattctttt tatttattgg aacttctttt gtactttcaa gtgcaatgaa aggtgctggt
    56221 gattccatgt ttgcacttat aagctcaata gtatctttat ggcttggaag acttccagct
    56281 tcttatatgc tttctaaatt ttttggaaca gacggaattt ggatgggtat tccttttggt
    56341 tggactttag gtcttattgt tacagttatc tactataaga aaggacattg gaaaactaaa
    56401 gctattgtaa atcatagaat caatgaataa tctttttata aaatgtattc acattcattg
    56461 tattcacctc cattatgata taataaatta tggaggtgaa tataaaaatg ggtattattc
    56521 ttaagccaaa acaattttat atgactgtta tagctaccat aattctctac ttctctctta
    56581 attacagttt caacataaaa ttttctatat gcttatcttt tttaactatc ttgatatggg
    56641 ctgtagactc agttgaaaaa acttttgttg cattgttttt tgtaattcta gcgtttatat
    56701 ttaacattgc accaataaag gttattttac agtttttatt tacagaaaat ttttacataa
    56761 taattcttgc atacataatt actaatgcag ttacaaaaac aggtgtcgca aaaattattt
    56821 ctgagaagtt aattttaaat actgtaaata cccctaaaaa aatgattctt ttatcgtata
    56881 ttttaggtat acttttaata ttttttatcc cacaaccatt tccaagggtt attcttgtat
    56941 ctgcttttta caaggagttt ttaaaagaac aacagataac tgaagattca aaatctatac
    57001 ttttatttag tatatttaca gcatctacct ttacatcaat gttttttgta aatggagaca
    57061 ctcttctaaa ttatgttgta ctagaacttg gaaattgtaa tataaattgg ggtcaatggg
    57121 ctttttatat gtctgttcca actataatta cttgttttat aacttatttt ttatttatct
    57181 ttgtctttaa aaaagaattg cattcaataa aatttatttc taatgaaaat cttgagggta
    57241 ataaacttca tttttcatat tctaatttaa aaaaagaatt taatttgcta aacaaagagc
    57301 aaaaacacgt atttttatgc ctaggaataa tgttttttat gtttttaact cagttcatac
    57361 ataacataaa cacattaatt ataatgtcaa tttgtgtact tcttttatta ctaagaaaaa
    57421 tagttggatt tagtacttta aaagaaataa attggaaggt ccttattttt tttatagcag
    57481 cattttcaat tggaggagtg ttaaagtact ctggagttgt agatataatg ggaaattatt
    57541 tgataaagtt tataccaaac tcttcagaaa ttatttcaat attgtttttg ataactctca
    57601 caataatctt gaatatatgt cttggaagtg ctgtcactac atcatctgta gtaataccat
    57661 tacttggaag tttacatata ctaaaggaaa atagtgttac tttatgtcta tttgtctaca
    57721 ttatagtaag catacagtac atattaccat ttcatcatgc tacaataatg gttggtcatg
    57781 gtgaaaatct gtataatagc aaggttattt tcaaatacgg tttaactttg attcctttaa
    57841 cctactttat aataatatgt ataacattcc cttggtggaa atttatagga ctagaaatct
    57901 aaaaaagatg aaaatatgaa ttgacttaag ataataacga aattattaaa aagaaaattc
    57961 atattttcat ctttttatat aagttcttgt aaaattggac aaaactgctc ttttaccata
    58021 atactaaata ttatttgttt tacttccttt tccaaaagta ttctcccaat cctctataaa
    58081 cttatctaca ctccaatcag ttaatggatg attcatcata gatttacaaa tatcatatgg
    58141 tactgtaaca ctatgcaccc catgttgcat taattctata acttgttgtg catttttaaa
    58201 actggctgca agtacttttg tatccatttt ataagtatct attattttta taagttctga
    58261 aaccatagct actccatcac cagatatatt atcaagccta tttacataag gtgcaatata
    58321 atttgctcca gcctttgcag ctaaaaaacc ttgatgagca gtgaatattg cagtagcagt
    58381 tatttttaca ccttttctgt gaaggtcttt tatagctctt aaaccatctt gtgttacagg
    58441 tatttttaca tatatatttt ttctcaaact acttatatat aatgcttctt ctaatatttc
    58501 ttcatacttt gtacttaaca cttgagcatg tataggcata tcctcaccta taatctcacc
    58561 aatttcattt ataagttgct taaaattctt tttttctttt gaaacaatac ttggatttgt
    58621 agttacacca tctattggta aacaagtaca taactcctta atctcctcca cattacctgt
    58681 atctaagatt agttgcatta aaatatcccc ctttaatctt tctttattct tattatatat
    58741 tgatttggta ttattttcaa cattttgctt attgtttttt attttttatt attgttttac
    58801 ttttccttct tagttttata atttttttat ttactaaatt ctaaatatat agttagaaaa
    58861 aacatacttt ttatattaaa ttaattttgt atttcatgtt aaaatagttg atatattgta
    58921 ttttatctta taatatttac tataatacta tattgcgaaa agaggtagaa aatgtttgca
    58981 gaagaaagaa tccaagctat attaaatatc ctaaaaaaag aaggtagagt tactgtcaaa
    59041 gagctcagtt ctaaatttaa tgttacagaa gattgtataa gaaaagattt aaaaaatata
    59101 gaaaagattt cttcaataag aagaatttat ggaggagctg tactagctag agaaacacta
    59161 gagaatcagg atacaaaaga cagaaaagaa attaatattc caacaaagaa aataatagca
    59221 gaaaaagcat ttaatttaat tgaagataga gaaactatat ttttagatat ctctacaatt
    59281 aacatcttgc ttgcgaagtt gttagctgaa agtaataaaa aagtaacact tgttacaaat
    59341 atgctggata tactaaatgt agttacttca aaaccaaata atttaaatat aatttccact
    59401 ggaggtttat taaatctcag tttagacggt tttgtcggta ctccaactat agagtttata
    59461 tcgaaatata agtttgataa gacttttatg ggaagttgtg gagtagatgt attcaactct
    59521 tcacttacaa cttttgaaat tgaagatggt cttacgaaga aggctataat aaattcaagt
    59581 aaaaaagtat ttatagttat ggaagataaa aagtttaaat ttgatggaaa tttcaagttt
    59641 gctcatttag aagatattag ttctataatt acagaaaaaa cgcctactcc tgatatagta
    59701 gatattttat cagaatttaa tgtaaatgtt ttataagttt aattatatgt tttataggat
    59761 ttcttataaa tataaatttt tatttgataa atattcttaa aaacatattt ctataatatt
    59821 tattttatcc ttagtatcta ttttttaaaa tctagttcta taacatctac tttatcctta
    59881 tgtctattta taaaactaat ttgaaataga ctttctaaat ctaatacagt tatttttaga
    59941 aagtctattt ccttaaataa actatttaat attactggct actttttata tgaatacaat
    60001 aatttgttat tcataaataa aagcttattt catttcattc ttcatttgct tctctaattc
    60061 tttagaaaat ttcttttgtt catatctttc catcatctca tcttttttca tttctaagtt
    60121 taccatagca ccttgtgcat catctttcaa atcttcagct gtatttttca taacataagc
    60181 tgtcttttta acaccttctt ttaaatcttc tttcatattt ttcatatctc tttttaatct
    60241 atccatcaaa actacctcct ctgtaaatat aatacttcct atatttattt ttcccaaagt
    60301 acatatattt atttgtaata tcaattataa tttttaagtc ttaaatatag tttaaactat
    60361 ctaaatctat acatttcaat aaattaaata ttttttattt caaaataaaa ataacactaa
    60421 gcatagatta tatgctcggt gttatttttt aaattcatag taacttaatt gttgggttac
    60481 tataatgatg acttatatgg aggatgtaag gaaatctcat cattatagtt ggtgtatttt
    60541 atggttttaa gcttctttat atttatataa tacagtttca ttatgaattt tttgtgattt
    60601 taaaatgaac tattattgaa agttatatat tctttataat aagtaattaa tttttaaatt
    60661 ctactgtgaa tactacagag ttttctttgt tttttatgct ataatcaaac ccatgacttt
    60721 taaaaatttg gctgactata taaagtccaa gtccacttcc tccagttttt cttgaacgag
    60781 atttttctat tctataaaat ggattaaata tttcttctaa ataacgtttc tcgatagtta
    60841 caccagtatt ttcaatttct aaaaccactc tttgattaga agttttttta cttattcgtt
    60901 tatttttatc atagagtcta attataagct ctgattcttc aggagaatat tttatggcat
    60961 tatttattat attattgatt gccttagtta ttctctcttg gtctgcttta atttccaaat
    61021 tttcttctat ttttaaaata gttttcatat gtttttcttc tattaaaaat acttgtctct
    61081 ttacaagtct atttaataat tcacttatat ttattgatac caatttcaaa tctttttcaa
    61141 gtatttctga ttttgaaacc tctatcattt catttactaa atcttttaat tcttgtgtac
    61201 actcatacga ttttttcaga taagtatccc tatccttata cttacctaca ctataaatca
    61261 taccttcaat ttgaccactt attatggtta ttggagtttt tagttcatgt gatattgtag
    61321 caacaaaatc cttccttcta tattcctgtt ctctctcact ctctattatg tttataagag
    61381 gctttgttat tacaattgaa tatatatatg ctccaataat cgctatcaat attgctattg
    61441 atatgatgta tggcattagt tttcttataa cttcgtttgc ttcgtcaatt ggttgtaatg
    61501 gcataacgag ttctaaagta tatggaccat cttttgcatc tttagtatat ataggtatag
    61561 aagttctata ctcatcctca agactattaa tcatgtactt actatatctt aaaataacta
    61621 cttcattctt accatataca attttacctt ggttatcttt taataaaata gccaaatttt
    61681 ggtctttagc catataataa agtctttctt ctaaagtata tgtatcgaaa tgaattgaac
    61741 tatctactaa agatttcaaa ctttcttgaa gagactcaat tttatactca tgataatatg
    61801 atggcaataa aaaatataaa attagatata ttattaaagc taatgctatt aataatgatg
    61861 tcgttattga aaataactta tactttatac ttaacttttc ccacttatca aatatccttc
    61921 tcaagtgtat atcctattcc ttttacagtt ttaatatatg gtaatgatat tttttttctt
    61981 atatttttta tatgtgcatc aacaatccta gtatctccat aatagtcata accccatata
    62041 ctatccaaaa gaccttccct agttataact tgtggatact tttctatcaa agcttttaat
    62101 atattaaact cttttagtgt aagttctata ggttctccat ctatctctgc aatatatgtg
    62161 tttaaatcta attttaattt ttcaaaaact ataaatttgt catttatagt cttgttactt
    62221 cgccttaaaa ttgcttctac tctttttata agaagattaa atgaaaatgg ttttgttata
    62281 taatcatcac attctaagtc aaacccttta agttggtctc cttcatcatt taaagcagtt
    62341 aaaaatataa ttggaacgct tgatgacttt cttatcattt tacaaactcc ataaccatct
    62401 aagtttggca tcattatatc taatattact aaatcataac ttccttgctt aaacttttgt
    62461 ataccttcca acccatcatt tgctgtatca acttgataac cttctgcact taaaaattct
    62521 gatattaact cttgtatatt tgaatcatct tcaattacaa gtattgacga attcattcta
    62581 tcaatccttt ctattttatt taaaatttcg tatattactt atattttatc ttattgttgt
    62641 gaattttaca tgaaaaaaga gctatcttaa tttgtaaatt aatcctttta atttaaagat
    62701 agctcttttg gatacatttt atttaattta ttaatctaat ctctcttata tgccttgaag
    62761 tttttaagtc taagtgcatt tgatacgact gaaactgaac ttaagctcat tgctgctgct
    62821 gcaatcattg ggtttaataa aggtcctcca aatacatata atattcctgc tgctacaggt
    62881 ataccaattg tattatatcc aaatgcccaa aataggtttt gttttatatt ttttatagtt
    62941 tcatgactaa gtttaattgc tgttggaaca tcaattaaat cactcttcat aagtactata
    63001 tccgcagatt caatggctac atccgttcca cttcctattg ctatccctat atctgctttt
    63061 gcaagagctg gggcatcatt tattccatcc cctaccattg caacaaactt tccttgattt
    63121 tgtagttttt caacttcttt tgacttatct tctggtaaaa cctctgccaa aaccatatct
    63181 atacctactt gatttgctat agcatttgca gttttcgcat tatctccagt taccattgca
    63241 acttttattc ccatatcatg aagtatttct attgcttttt tactactttc tttgactaca
    63301 tctgcaactg ctattatacc tgataaattt ccatctacag ctatatacat aggtgtttta
    63361 ccttggcttg ccaatatatt tgatttttct tctaaatccc caagctttat attattgtca
    63421 ttcataagct ttctatttcc aagtaatata ctttcatcat taatagtaac ttgtatacca
    63481 gcacctggta tagctttaaa attatcaact ttttcaaatt ttatattctt ctcttctcca
    63541 tacttaacta ttgcttctcc aagaggatgt tctgaacctt tttctgcact tgaagcaatc
    63601 ttgataagat attcttcttt tacattatta tttaatacta tatctgttac ttttggcttt
    63661 ccttctgtta tagtacctgt cttatcaaat atcactgtat ttactttatg tgcagattct
    63721 agtgcctctc caccttttat caagattcca ttttctgcgc cctttccagt cccaaccatt
    63781 atagcagttg gtgttgctaa tcctaatgca caaggacaag caattacaag tactgatata
    63841 aatatagtaa gtacaaatac tatatctttt cctcctatta aaaaccacaa taatgatgca
    63901 actacagcta ttgcaattac tattggtaca aaatatccag atacagtatc ggcaagttta
    63961 gcaataggtg cttttgtacc ttgtgcatct tcaactaact ttattatttg ggcaagagca
    64021 gtatctccac caattttttc agccttaaac ttaataacac catttttatt aatactagct
    64081 cctgtcacct tacttccaac attcttttct actggtatac tttcacctgt aagcattgat
    64141 tcatcaactg atgtatatcc ttctattaca actccatcca cgggtatttt agttcctggt
    64201 tttaccaata gtatatctcc tatctctact tcttctatag gagtttcaac ttctttacca
    64261 tcaactaaca ctattgcagt tttaggttgt agccccataa gctttttaat tgcttctgat
    64321 gtttttcctt ttgattttga ttctaaatat ttaccaagta agataagtgc tattattatt
    64381 cctgcacttt cataatacaa ctgatgatgg tgcatacctt gaatttgtcc attggctatt
    64441 tgtagtgtcg tatatagact atataaaaat gcggctaatg ttcctattgc aactaaagaa
    64501 tccatattag ggcttaaaga aaaaagtgat ttaaacccat ttatataaaa tttataacca
    64561 gctatcatta ctggtattac taaaattaac tgaattaatg cataattaaa agtatttgtc
    64621 ataggattta taatttctgg caaaggccat ggccctatag gctttattat cataggtccc
    64681 attgctatat aaaacagagg tactgcaaat actattgcaa ctataaattt aacaaataaa
    64741 gacttcattt ctctttcttt tctcaattta tcttcatcca catcaacctt atttcttacc
    64801 tcttctattg gtttatatcc agctttttca atagctgctt ttatttgaga taattttact
    64861 tttgatgggt catagtctat attagcttta tctgttgcaa tattcacact aatactttct
    64921 actccatcca atttttttac cactctctct acagcttttg cacaagctgc acatgtcatt
    64981 ccatcaattt tcatatcaat ttttttatta ctttcttcct ttataattcc atatcctgct
    65041 ttttctacaa cctgctttat atcatcaaaa ttaaccttag aattatcata ttctatttta
    65101 agtttttcag tagctatatt tacactttgg tcatatactc catccatctt cttagttact
    65161 ctctctactg cctttgcaca agctgcacat gtcatacctg taattttata actttctacc
    65221 actttatttg aactcataat aaaatcttcc tttctttcaa tatattttca gctaatttgt
    65281 aacgttttat tttgatatgt aatattgata aattacttat ttagaaatct atatttttat
    65341 tataccccct ataggtatat taaatcaata tttttttaat aaataaatgt attagttata
    65401 tttatttgta tttaatagaa aagtatactc ataattaaat gtatatataa aaatagagca
    65461 tctaaattgt ttaatgctta tacaatttag atgctctatt tattatattt tatttaaaat
    65521 ttattcttta catgcttcaa aaaactctgc ttctgtttcc tttatttcaa gctcattgtc
    65581 tattattcca acagcttctt ttttaaatgc tctacactga cctatacaac cagtctttac
    65641 attttcttct ccaaccaaag tttttagctt atttacatcc acatttgaac agtttggaca
    65701 tactcttatc atatttaagt tcctcctaat taatgtctaa ttaatacttt tatacccaaa
    65761 tataaacttt ataaaagttt ttttaatata aattattacc atatatacca tttatatcct
    65821 attgcgagta ttacatatta attttatata ttattaatac tacatatacg gtggtatctg
    65881 ttgttttctc actatttcca attccttaat ttctaaagac ttaatcacat ttactttata
    65941 gttttcttta gactttatat acaaaacatc ttctatcttt ttaccttcaa taaatttatg
    66001 agaccactta agaagttctt caaaattaca aacttcttct tttacaaaag tatcactttc
    66061 acttgcaaaa tatttaatta ttattttggt tacttccaac atatatcatc ctttactctt
    66121 ttattaatct ttttatctat taaagttatt atttgtctaa aaaatttttt taaacagaat
    66181 aattttcaga tgcaaaacta acagttttat ccaatttaaa ctatattaat acaatttaat
    66241 atattcctcc ttgtacctaa taatatattg tgctataatt aataagttat tttaatcgaa
    66301 gggagcaaca aaaatgtcac aaaaacataa aattataaat atcgcagtta tagcccacgt
    66361 tgacgctgga aaatcaacat tggttgatgc tttcctttct caaagcggtg tttttagaaa
    66421 gaacgaagta gttaaagact gcgttatgga cagtaacgac cttgaaaaag aaagaggcat
    66481 aactatatat tcaaaaaact gtgcaataaa ctatgaagat tacaaaataa acatagttga
    66541 tactccagga cacagtgact tttcttctga agttgaacgt gttatgaaaa ctgttgacac
    66601 agttattcta ttagttgatg ctagtgaagg cccaatgcct caaactagat tcgttttaca
    66661 aaaatcttta gagttcggtt taaaaccaat attatttata aacaagattg ataaaaaaga
    66721 ccagagagcg gaagaagtag ttaatgaagt tttcgattta tttgtagact taaatgcaac
    66781 agatgagcaa tgcgaatttc ctataatata tggtattgct aaacaaggta ttgctaaact
    66841 tgaaatggat gatgatagtg aagacctttc tcctctattt aaaactattg taaatcacgt
    66901 tgaagcttat cctaattacg ataatgaacc tctacagttc caaatatcag ctcttgcata
    66961 tgatgattat gtaggtagac ttggtatagg tagaatttac aaaggtactc ttaaaaacaa
    67021 tacacaagtt gctatatgta gagaagattc tgttgtatct aaaggaaaag tatcaaaact
    67081 ttctgtgtat gaaggtttaa aacaagttga agttgatgaa gctactagtg gagaaatagt
    67141 tgttatagct ggtattcctg atatatctat aggtgaaact atatgcgatt tagatagtcc
    67201 actacctatg gaaatgataa aaatagaaga gcctactctt tctatgaact tcttagtaaa
    67261 cgactctcca ttcgttggaa aaagtggaaa attcgttaca actagacatt tgaaagatag
    67321 acttgaaaaa gaacttgaag taaatgttgg tcttaaagtt gaacctcttg atactactga
    67381 tggatacaaa gtttctggac gtggagagct tcacttatct atactacttg aaaatatgag
    67441 acgtgaaggt tatgaagttg gtgtttctaa acctgaagtt ttaatgcata aagaagatgg
    67501 aaaactaatg gaaccaatag aaagagttgt tgtaaactgt cctgaagttt actctggtac
    67561 tattataaat gaattaaaca tgagaaaagg tatgatggag tctatgtcaa tagaaggaga
    67621 ctatgtaaaa atagagttct tagcacctac tcgtggtctt ttaggatatc gaagtgaatt
    67681 tataaacgct actcgtggag aaggtacttt agttcgttca tttgaaaaat ttgaagaatt
    67741 taaaggagaa ataccttcaa gaggaaatgg tgttttaata gcacaaggac ctggtgttac
    67801 tatggggtat tctcttaatg ccttaagtga tagagctgta atgtttgtag accctggtgt
    67861 agaagtttac gaaggtatga taattggtat gaattccaga aaagatgata tggtagtcaa
    67921 tccttgtaaa aacaagaaaa tgagtaacgt acgtgcttct ggttcagatg atgctataaa
    67981 attatctcct cctagaatat ttactcttga agaagcacta gagtttatag aagatgatga
    68041 attagttgaa attacacctg attctataag acttagaaaa agattcttaa atgaacatga
    68101 tagattaaga tataacaaat ctagacaagg taaataaaac gtacatttac ctctaattaa
    68161 caaaatagcc atatagtact gaaaaattat ttcagtttat atggctattt ttatttgaaa
    68221 tttatattat tcaacattta tataattagc tgcttgaacg gctgcaatag ctccatctga
    68281 tgctgctgtt attatttgac gtaaaaactt agttctacta tctcctgcta catatacacc
    68341 ttctactgat gttgtacaag actcatctga aattatatat ccaccttcat ccaaatcaag
    68401 aacattttca aacattttat tattaggttt aagacctata gcaataaaaa taccactaac
    68461 atctatagtt cttttttctt cagtctttaa gttttttact tctattttcg atacagtctt
    68521 ttctccttct attttttcta caccatgact gtaaagtatc tcaatattct ctcttgcttt
    68581 cacagatttc tccaacactt cttcacctct aaaactatct cttctgtgaa ttaaatacac
    68641 ttttgtacaa ttattagcta aaaataaagc atcttctagt gcagtatttc ctccacctac
    68701 tatagcaact tctttatctt taaaaaaggc tccatcacat gttgcacagt aagatactcc
    68761 tctacctgta aattcttgtt cccctgcaca acctaattta cgtctttcaa ctccatttgc
    68821 aagaataaca gcctttgctt tatgttcacc tgaagaagtt tttacaacct ttacttttcc
    68881 ctctaaattt atctcttcaa cctcatcaaa ctgaatatca acaccttgag caactgcttg
    68941 attgtatata ttattagaaa attctacccc agaaatcttt tgaactgctg gataattttc
    69001 tacctcagag gtacttgcaa cttgacctcc ataaatattt ttttcaaata ctgtaacgct
    69061 taaccctgct ctcatagcat aaattgctga agttaaacct gctggtccag caccaattac
    69121 aatgatatct accataacgt ttacctctct ttatattatt atttcttata tattattctc
    69181 atcattctta tactttacta ttattatcca tatatactat aaacaaaaca ttatttttta
    69241 ttaattaact ttattttaca tatatataaa aaaactgcaa ataaaaatta acttttattt
    69301 acagttctca cttatttata taattcaaaa ccttattggt tatcatttac agtgtcttct
    69361 aatatattgc tttctgatat atatgataga attgaaagtc catacataac caaaactaat
    69421 gctgctgtta taagtactat tcccatattt aatacctcct tttgtttaca gtatactatt
    69481 attatgtgaa atatttatga atttaatttg aatatatatg taatttcaca ctaacaattt
    69541 cttcaaatta aacattatta actatatact tttgttgaac caattatgat taatagttta
    69601 aatattagca ctatttactt atatttatat gatataccat ataattacat ttttcaaatt
    69661 aaagttttgt aaactttttt tgtaatatag tgtagtataa aattgtaata ttacagatat
    69721 ttaatagtta tcttttgatt actttcatta aaaacagctt catcactatg aaaatctagg
    69781 tttttaaact tttaaaaaag ttaaaaaaat atttttctaa tactcaattt gattacaatt
    69841 tttttacaat ttaaaaaata ttttttccaa atttttatat taatacttga ctttgtctgt
    69901 tttataaact agaataatta ataatattaa gaatattgaa aggcattgat taggaagagt
    69961 aaatctgaat cgattaccag agaaggaaac tactagctga aatgtttccc taattagaag
    70021 gattgaaaac tacctaggag cttctatccg aagttatctt aatgatttta gtaggaatag
    70081 acgtttttat tacttgcgtt aaagtatcaa gtggattttt taaaatcaat ttgggtggaa
    70141 ccgcgggaaa cagattctcg tccctttttt agggatgagg gtcttttttt attacctaaa
    70201 ttcagttttt aaaatattct gtatctaatt taattagcta attaaaaatt taaaatatat
    70261 ggaggattat aaaaaatgta ttattcaagt acgagaggca ccgaagaaaa agtaactgca
    70321 tcacaagcaa taataaaagg aatatcaagt gatggtggtc tttatgttcc aagtgaattt
    70381 cccaatgtaa aaaatgaact tataaattta gtaaatttaa cgtattctca gatagcattt
    70441 tttgtactta gtaaattttt atgtgatttt actgaagatg aaattaaaaa ttgtatagaa
    70501 aatgcatatg atgaaaagtt tgattgtagt agtatagctc cattaaataa agtaaatgat
    70561 acttatttct tagaactata tcacggtcca actttagcat ttaaagatat ggcacttact
    70621 ataatgcctc atcttcttaa aacatctata aagaaagata atttagagaa agatgttgtg
    70681 attcttactg ctacatctgg agatacaggt aaagctgcac ttgagggatt taaagatata
    70741 gataaaataa agataattgt attcttccca gaagatggtg taagcccagt acaaaaactt
    70801 caaatgaaaa ctcaaactgg aaaaaataca tatgtagttg gtataaaagg aaattttgat
    70861 gatgcacaat caggtgtaaa gaagattttt tctgataaag aatttaatca aaaactattg
    70921 gataataatt atatattatc ttctgcaaat tcaattaata taggaagact tcttccacaa
    70981 gttgcatact atttttattc atatatgaaa ttagttagca atagtgatat aaatttaaat
    71041 gataaaataa attttgttgt cccaactggt aattttggta atattctagc tggatattat
    71101 gccaaacaaa tgggtcttcc aataaacaaa ttgatatgtg catcaaatga taataatgtt
    71161 ctttatgatt tctttaaaac tggtgtatat gataaaaata gaacattgaa attaactact
    71221 tctccttcta tggatatatt aatttcaagt aatttagaac gattactgtt tgaaatatca
    71281 aatagaaata ctgatattgt aaataagctt ttatcagacc ttagtgataa aggagtctac
    71341 aaaataagtg atgatatgga aaaaaattta gcctcattct atggagaata ttcaaatgaa
    71401 gaagaagtta aaagcacgat aaacaatgtg tttaaaaatt ataattattt gatagatact
    71461 catactgctg ttgcatacaa ttgttatgaa aaatataaaa aagaaacttc tgataacaca
    71521 aaaactgtta ttgtaagtac tgcaagtcca ttcaagtttt ctgaagatgt tctaaagtct
    71581 atagattgtg attttaaaga ccttgatgac tttgctataa ttgatagatt atcaagtatt
    71641 tctaaaatag atattccaaa acctattaaa aatcttaaaa atgcagaaat actacataaa
    71701 gatatttatg aaaaagatga attaaaacta gctataaaaa aattcttaaa ggtataggtg
    71761 attattatgt tagagattat agttcctgca acaagtgcta atataggtcc aggatttgat
    71821 tgtcttggaa ttgcgttaaa tatatacaat aaattttatg ttgaagaaat tgaaagtggt
    71881 cttgaaatag aaggttgtga agatgcttac aaaaacgaaa acaacttagt ttatacatct
    71941 atgaagtact tttttgatag agttaaacca gaaaaaatac ctgctggtat caaaataaaa
    72001 atccaaagtg aagtacctat atgtagaggt cttggcagta gtgcctcttg tatagtagct
    72061 ggagttatag ctgcaaatgc tctatcaggt gctaatttag ataaaaatca attactaaat
    72121 atagcttcag aaatagaagg tcacccagat aatgttgctc ctgctatttt aggaaatatg
    72181 attgtatctg ttactgataa tgagaatata cattatgata ttataaaaat tcctgaagaa
    72241 cttaaatttt gtgcaatgat acctaatttt aagttatcaa cagaaaaagc tagaggtgtt
    72301 ttaccaaagg aaataccata ttctgatggg gtattcaatg ttagtagagt tgctttacta
    72361 atatctgcct tactaaacaa aaactttgac ctacttaaag tagcttgtca agacaaattg
    72421 catcaagatt atagaggaac tctaattgag aactacaatg atattgttga aaaatctgaa
    72481 caattaaata gtattggagt atttttaagt ggagctggac ctactataat gtctttaata
    72541 aaagaaaatg atgatagttt tgtggataat atgaaaaatt acctacaaaa actaaaatct
    72601 gattgggaaa taaaagagtt atgttgcgat tctaatggag ctgttttaaa tataatataa
    72661 ttatcgtctt ctatacaaaa tataactact cttttattat aatttgtagt ataataatta
    72721 ggactaggta ataatattaa gtattataat ctagttcttt aaacatgttt acattgagga
    72781 gggattatca taaaagagtt aataattaga gatttagttg caaaagttcc tataattcaa
    72841 ggtggaatgg gcgttggtat atctaggtca tcactagctg gtgcagttgc taagcttggt
    72901 ggtgttggtg taatttctgg agttcaaatt ggatatgatg aggaagattt tgaaactaat
    72961 actataaatg caaatttaag agctataaaa aaacatattt ctaaggccaa agaaatctca
    73021 aatggtggta ttattggtat taattttatg gtagctatga aagaatatga aacatacgta
    73081 aaggaagctg ttaaagctgg tgtagacctt ataatatctg gagctggatt acctaataag
    73141 ctaccatcat tagtaaaggg aagtaatgta aaaatagcac ccatagtttc aactgcaaaa
    73201 gctgctaatg taattttaaa aatgtgggat agaaaagaga aaactactgc tgacttaata
    73261 gttgttgaag gtccaaaagc tggtggtcac cttggatact ctaacgagga acttgataac
    73321 atagattcta tagactatga taaggaattt gttgaaattt taaaggttgc aaatacttat
    73381 ggagaaaaat ttggtagaaa cataccagta gttgctgctg gtggtataac ttctagtagt
    73441 gatgttaaaa aatatataga tatgggtgca agtggtgtac aagttggtac aagatttgtt
    73501 gctacttacg aatgtgatgc ccatgagaac tttaaaatgg catacataaa tgctagtgaa
    73561 gaagatgttc atatagttaa aagtcctgta ggtcttcctg gacgcgccat aagaaacaaa
    73621 tttatagaag aagttaaaat aaatcgtcca gaaataaaga agtgctataa ttgtttgatt
    73681 ccttgtaatc caaaagaaac tccttactgt atttctcaag ctctaatcaa tgcagttaaa
    73741 ggagatgttg aaaattcact tttattttgt ggaaatgatg cctataaaat tgataaatta
    73801 agtactgttg aagatgttat caatgaattg atttctgaat tataatttaa agaaaactaa
    73861 attaaaattt tatcaagcta aggagtttaa atacgttatt tattaatctt tataaacata
    73921 tttatgtcct tagctttttt gtgtcaattt ccttttatgg aaattttaat ttaattagag
    73981 atagtattaa cctttataac taatcttctt ttacaagtac attggttatt tcagctatat
    74041 ataaagtatg ataatctttt tgtggatacc atcttccatc tataccttca gcaataaaac
    74101 attgaggttc aagtttctga ctatacattt ttttgcatat aatagccatt ttagattctt
    74161 taaaataagg tgtatcattt aagtgttcta tattaaatcc aatctgtgat atcttatcct
    74221 cttctctacc agatactttt ccacaatatg aaagctcttt acgaaaatct tcatcaaaaa
    74281 atgtaagaga aaatttatct gtattatcta taaattcctt agtataacgc tgtggtctta
    74341 ttactacaaa agcaacatct tttccccaca taactccaag ccctccccag ctagcagtca
    74401 ttgtattcac tttaccttca ttttctgctg ttataagtgt ccaatcttta cctatcaatc
    74461 caaatggatt atttttaatc tcttctgcca aaatttcttt aaaatcactc atatctctaa
    74521 taacctctca ttctcttata tttatattcc ttttattttc atgataaatt ataaatgaag
    74581 tctagttttg aaaataaaat acttttttaa atatattatt gcaaataagt aaatatatat
    74641 atacactctt attttttaat atatttaata atttcactca gaatatatat attctttact
    74701 caaattaaat ataacttata tactttatgt gtaaattatg gtaaaaatat tatttaatca
    74761 aatcaaaact tgatttatat acctggaaaa ggtattatat taaagagtgc ttaaaatacg
    74821 cgtttcataa atagctatat ataaaataat aaataaggag agtgatgggc aatggatact
    74881 agtccgttgc ggagagaatt ttttacattt tcatcactta ataatatcta aaatcaaaac
    74941 taatacatat attcagttat ataaattagt taattaatag atactattaa atgatgagat
    75001 ttatataaaa ctgaataaag gatgtgttgc catgataaga tattacaaaa ctatagattc
    75061 aaaattagag aaacttagtt tttttgaaga tggctgttgg ataaatcttg ttgaacctaa
    75121 tcatagtgaa atcaacgaaa tttctaattt attaaatata gatgtagaaa gcatagaatc
    75181 tgcactagat gaagaagaac gctcaagaat agatgttgaa gacaatcata ctcttatact
    75241 tatagatata ccagtagacg aaagtgactc taattcttct cattatacta caataccctt
    75301 aggtattata ctaactgaag aagctattgt aacagtttgt gatgcacaaa ctaagatttt
    75361 aaatgacttt atagttggtc atattaaaga tttttttacg tttaaaaaga ctcgcttttt
    75421 gcttcaaatt cttcacaaaa atgcagctta ttacttgcat tacttaagaa aaataaataa
    75481 aatgacaatc ataatagagc gagaaattta caaatcaatg aaaaacaaag aattggttca
    75541 attattggaa ttagaaaaat ctttggtata cttctctacc tcactaaaat ctaatgaact
    75601 tgttttaaac aaaatggtta gaactgctgg tataaagaag tatccagatg atgaagacct
    75661 attagaagat gttatagttg aaaatagaca ggctcttgat atggctaaaa tatatggaga
    75721 tatattgagt agaattatgg atgctttcag tgcaattata agtaataatc agaataatgt
    75781 tatgcaaatt ttaacagtag ttacactaat tttctcaata cctacaataa tatcaggatt
    75841 ctttggtatg aatgtcatca acatgccatt ttctaataac ccaaacggat tttggataat
    75901 acttcttatt acctctataa tatgtatagt gattacattt ttcatgtcaa gaaataagct
    75961 attataaaat attaataaaa aagccattag aattaattga tttacattta tcctaatggc
    76021 ttttatatat ttaaatctat ataatcttat aatacttttt aactatcatg ttcttcatct
    76081 ataatcattt cagtttcaag cccttctagc attgaatcta aactttcttt tatatttagt
    76141 atataaattg gtacatactc ttcttcatct attacctctt cttgcaactt aaatggagga
    76201 attaatactt catcaaagtc tatatttaaa tttggaaagc cttctactat ctcttcacaa
    76261 ttatcgtact cttcatttgc taaagaaatg tacatatcta ggctcttttt ataataaaga
    76321 cctgcaagca tatactcaca cttcttactt ccatatttaa taccttcttt ataatatttc
    76381 tcagcttctg cgtcatcatt taattttaaa taaatttgac ctaaattata tattgattca
    76441 acacaacctt gtgctctagc cttttcatac caaaatttag aatttacata atctttatag
    76501 aacatatcat aaattaatcc taccatatgt tgagcataca cattattttc attggcaggt
    76561 gtatcaaaca tcattttaga ctcttccaat ttaccttctc taaaataaat tctacctaga
    76621 tgtatacgag cattcatatg gtttttgcta cttgccattt caaaatactt tctagcattt
    76681 tttgtatttc ctaagctctc atatatacac cccaatctat aactagacct cgtatctcca
    76741 ttttcagatg ctttcttata ccaacttatt gcttcttcaa tattatttaa atcttcatag
    76801 atatttccta atttgatttg acaagataca ttatttggaa tcctcgaata atacgaaatc
    76861 gctttttcta tatcttgatt ctgataatat aaatccccta gattttcaag ggaacttttg
    76921 catccaacag ctatagcatc ctcataatat ttaatagcat tttcataatc tttttcttca
    76981 aaatatatac ctgccagatt attttttgct tctgttatat catcttcagc agccatttta
    77041 taataagttt ttgccttctc tatctcattt tctctattat ataaattagc aagtctatac
    77101 ttagaaagtg tatgattttt ttctattgct ttctcataat aataaattgc atctcccagc
    77161 tcttcttttc tatcatatac atatgcaagc ctatactcag acttcacatc atctctatca
    77221 gcactctttt tataatactt ctctgcatct tctaaattat catttatttc cataatcata
    77281 cccaagttaa agcaaccttt catatgacct gacttgtaca actgtttata taaacttact
    77341 gttgatttat tatctttctt ttttccattt aatattgcta aattatattt tgcatcatca
    77401 tctaaaagca cagaaccttt tttatagtat tcatatgctt catcatcttt ctccaaaaaa
    77461 gtatataata cccctaaatt aaaacaagct ttacctaaat tcttgtctgc tgctgttttt
    77521 aaccattttt cacaccttac aaaatctttc attttaaaat ggcatacacc taaattattt
    77581 tgtgcttgta aataacctaa atttgctatc ttttcatacc aatatatagc atattcatag
    77641 ccatctaact tatagtacat attacctaaa tcaaaagcag catcttcact tccactttta
    77701 tatgccattg aataccactt ttctgcttct ttaaattgtt ttttactttc atatatattt
    77761 cctaaagtat attgagattt tacgtaatta tccaatgcag cactcttata caactctatt
    77821 gcgctttcca tcttacccat cttttcaagg agggcaccct tagtatgtac gactttcggg
    77881 tcattagata tattttttat tttttttata gaaaattttg tatttttcat tattcgctac
    77941 ctacccattt tataaaatat attctctcaa acattattat acattataat ctacaattaa
    78001 tgctataata ttgaattttt accttttgtc actatattgt aacattaaat tttaaatttt
    78061 ataatcatta gattttatta tgtaattggt atataatgta tatatagggg ggacatttta
    78121 tgaatttcag caatattttt atccaagttg cagttttatt tataattatt ttagttggat
    78181 attttgtcag aaaattcaac ttattagatg accactgcac atctaagctt tcaactttga
    78241 caatgacagt ttttttacca tcaatgataa ttagctccat gcaaattaac tttgatagta
    78301 aaatgataca aaaaatacta ttgttattat ttacatcttt gattatgtat atagtttcaa
    78361 ttataattgc atttttattg aaatacattt taaaatgtaa tgataaaaaa gatttgggaa
    78421 tataccagta tatagttgtt ttttcaaatg ttgcttttat gggttatcct gtaattgaag
    78481 cagttttagg tcatgaagca atattctata ctgcaatatt caatttgcct tttaacttat
    78541 tttctttcac tttaggaatt tatcttttat ctaaaggcag tacaagtaga ggtttttcaa
    78601 taaaatcact tataagccct gctacaatag ctattgttat tggacttttt ttatttgtaa
    78661 caggacttag gttaccccaa tttataaacg agccacttga gatgttggga agtataacta
    78721 caccaatatc catgattatc attggaagct tacttgctaa ttcttcagct ctcgattgtt
    78781 ttgtcaacaa aaaattatat atagtcactt ttataagatt attggtactt cctgtgattg
    78841 tgtattttat tctaaaagga tggataaatg ataagatgat tttagctata ccagtagtaa
    78901 tttcttcaat gcctgctgct gcaaatactg ctataatggc taatcaatat gactccaata
    78961 taacactagc ttcacaatgt gtgtttttta caacactatt ttcagttata tctatacctt
    79021 ttataagtat tttactctta tcttgattta tttttttatg tattatataa taacatattc
    79081 aataaattac aaatataaac attttattgt agtatattga tggaattttt tcctagatat
    79141 ttgtcaataa tatctatatg tattatagaa taggaggctt aaatatggat atggatttac
    79201 tctttaaaat agtatttgct atagttgcta taggtgtttc tgtaaaaatc attaaaactg
    79261 ttgctagttt agcttttaaa atagcgttga tattgctaat aattttattt gtatatagaa
    79321 tgtttttgta aacatttaaa aataagtttt ttaacacaat agagaagtaa aatagattat
    79381 ctttaatgta aattttttat taaagacact ctattttact tctctattag cttatttaaa
    79441 ttaaattttt attatatctt cccataatat aaacatcttc aaattttcca tctctgatta
    79501 cagcatattt tttagttccc tctatttcaa aacctagctt tttatataaa tttaatccct
    79561 tttcattatc cacaattact tctaatccta ctctagttaa cataatccaa ttatctgcta
    79621 tatctaaaag ttgttccata agcttcttac ctactcctct tccctgataa ttctctgcaa
    79681 cacttattcc tatttctgcg ctatgtctca atcgtggaga agaatttaca tgtaacccag
    79741 caaaacctat tacatctttt tctccattat tattagtttc agctacaaac atataatcat
    79801 tttctcccaa agaagctaac atagcttcag ttttatcgac tctgtcactc attaatgcca
    79861 aagtatttct cataacactg tatgttcttc taatttcatt aaaagcttgt gcatcttctc
    79921 ttcttatagg tcttattgtt atatctatag gcttactcat attggattcc ccctcaaaca
    79981 taatctttat ttttaattaa aattttacat ctttatttta tactgttcaa atctatgtat
    80041 gcttctacct gaggtacata tatcatatta tcttttatat gtgtacttcc aaattctttt
    80101 aattctgtac cttctttatc cttagttatt ttatatctaa tggattccat accttcaact
    80161 acttcagcat gaaaaaacat accttcatat tgtttaaatc taaaattaaa attgtcttta
    80221 gtaagtttta ttatcatatt tttatctact ccttatataa ttgatatttt tcttattatt
    80281 agttgtatat atactgctta ttcatattaa tatattataa cttatcattt atttagtata
    80341 aagttataaa tagatatatt tatacttatt ttacaatctt tcttcaattg atatataata
    80401 tgtttatata aactaatgta tgtgaggtga aatatgagca aaaaaacaaa atatttttct
    80461 ttaattctct ttcctattgc tttgctttta aattttatag ccagtaaagt tccaaatatt
    80521 gttgaaaaat attactccca attcatagat aaaataattg tacaaatatt gagtaaagtt
    80581 tctggaattt tcccattttc tctctatgag attacaatgt acataatagt tatatctatc
    80641 ttcttatttt tatgttgtac tttatctaca atttttaata agaaaaaaaa attaaacata
    80701 tatttaaaaa attccatttt aaatatatta tccattgtat caatagtcta ctttcttttt
    80761 gtagtgcttt ggggaataaa ctataatagg attccactag aaaccacact tataaataac
    80821 tataatttaa aaaacaatac ctctatccaa tcaaaacaat atagtgttaa agagcttact
    80881 aaattatata aattccttgt aattaaagca aatgaaacta gaaaactcac attacaagat
    80941 aaaaatggta ttgtaaaatc taatacagat tataatggtg tcataaatag agctcaacta
    81001 ggatacgata atatcttgga tatattacct agtgttagtg gtagttattc taagcctaag
    81061 tatattattt catcaaatct aatgtgctat acaggaataa ctggtatata ctttcctttt
    81121 acaggtgagg caaatgtaaa tatagcaata cctgacttat atattccttg tacagttgaa
    81181 catgaaatgg cacatcaaag gggatttgct agtgaagatg aggctaattt tatagcgtat
    81241 cttacttcta taaaacaccc caatattgat tttaactatt ctggatatat tttagcttta
    81301 aattatactg cttctgcttt aagtaaggtt gattataatg catatgttga tatttctgct
    81361 ggcattttag attctgtccg tagagattta aaaaatgaaa gtgaattttg gcaaaaatat
    81421 gaaggtaaaa ttaatgaaat ttctaatgag tttaacaatt cttacttaaa agctaatggc
    81481 gttactgaag gtactcagag ttatggtaaa atggttgatt tattgctaac ttattatgaa
    81541 ttatatccat ataactaaac actacaattc aaaattttat tcatatacag ctgatattaa
    81601 atcagctgtt ttctatttaa ataaattatt taacttcaag caatcttata taatttgata
    81661 gtacttatac tatctgtata acatatcaat tctaactatt ttagttaaaa catttctatt
    81721 atctttttta ataaatgttt taactaaaat ttttaaaaca taaaacttcc acattatttc
    81781 actatctata taaaaatcta aaatttcaca tataaaatta cataactaaa aaatcataaa
    81841 tttatagaaa acatatattc aaaataaaaa agcatgtatc aaaacttgac acatgcttat
    81901 aatcttatgt atatatatca ttttgtcaca ataaaaattt acttgtaaca ctgatatttt
    81961 taaacaaaat agtccttatt taattaaatt aacattaatt aaattcgtac tcattttgct
    82021 atcattaaac attacttata gtaattttct aatacactat ttgaaacttc cttcccttga
    82081 aaacttttca accaattctc atatgctgag tttttccata cactaccatc attaaatgtt
    82141 acttgtttta cacaagatat aatgtacttt acaccatgct ctccagttga ttgtttccat
    82201 ttatcaaaca atagaaaggc atcattttga ttcttacctg gtgctattgc attttgcttt
    82261 gcatattctt tctccatttg tttccattct ttcaaccaat tttctaccca tgccttgcct
    82321 tgttgttttt caaacatact tattatatcc tgtggtggtg attgttgcat ttttctataa
    82381 gtatgtgaat atgattttgg agacacagga gatatgcctg taacaatacc atagtctaca
    82441 ccagctgggc taaatccaac acttcctact tcgccatctg ctgccacatt ttgagcatcc
    82501 caatatagct caagtggttt tccattttta tcatatgcta agcatgtaat ttcataatcc
    82561 ataattgcct tttcactgct atttgttaag cttataacat tgctaggcca atgatatgga
    82621 gtatcatcat actgtatttt gctattattt ataaataatg gaatattctc attataaaca
    82681 agacctttac tactttgaat atctgatacc ttctttgtga cagtacttac cgtatttgct
    82741 aagtatacat ttgttttttc tgaattggtc gtactaagag aaaatgttgt tgtcgttcca
    82801 gtaatcagca aagcaacaac taaaataggt aagctagata tttttttata tctcacaatt
    82861 cttcacctct ttttctatta acttataata aaacaattta ccaaaacatt aaaatctatg
    82921 ttaacataat ttaccaactg ttctagtaac tatatcctat catagttact atcaagtttc
    82981 aatactattg atggaaattt tcactatatt aaatcttttt ttaattttat aaatttacaa
    83041 tatgatttaa ctcatacata tatagtcaaa ttagaatata agtttcttac atttaatgaa
    83101 gtttataaaa taaaaaatga ctagataatt aaatactgta aataaaaact tattacaaaa
    83161 gtatttaaaa atctagtcaa ttaatatata tatgaattgt atactataat ttttcaatct
    83221 cttctagcaa ctcatcaact aatttgttac catcaatcat tctaactatt tcaccctttt
    83281 taaataaaag accttcacct ttacccccag caatacctat atctgcctct ctggcttcac
    83341 caggtccatt tacagcacag cccataattg caacagtgat atttttttcc atactaccaa
    83401 tcttttcctc aacctcattt acaacactaa ttaagtctat attacatcta ccacatgtag
    83461 ggcatgatat aactttaatc ttatcattta aaagtcccaa acttcttaaa atctgtttac
    83521 caacaataac ctcttcaaca gggtcgcctg ttaaagatat tctaacagta tctccaattc
    83581 ctttaagaag aagtgctcct acccctatag aagactttat tgttcctttg tgaacacttc
    83641 cagattctgt aattccaata tgaagaggat aatcaacttt ttttgatatt aattcatatg
    83701 catcaacagt tttataaata tcggatgatt ttagagatat aactatatta tgaaaatcta
    83761 agtcttcaag aatcttaata tgtcccattg cactttcaac taatgcttca gcagttgcag
    83821 agccatactt ttttaaaagt tctttctcta aagaacctcc attaactcca attctaattt
    83881 ttaaatttct ttccttgcat ttctcaacta ccatcttaac tctctctata cttccaatat
    83941 taccaggatt tattcttatt ccatccacac cttgttctat agcttcaagg gctagcttat
    84001 aatcgaaatg tatatctgca ataattggta tatttacact agactttatc tttgctatat
    84061 ttttagcagc tttaatatca ggaacagcaa ctctaactat atcacaacca gcttcctcta
    84121 atctctttat ttgagctatt gtagcatctg catctcttgt atcagtattt gtcatagatt
    84181 gtatacttat aggattttct cctcctattt ttacagttcc tacacttact tctctcgtct
    84241 ttcttctctc gtaactcata ttccacctct atatattatt ttatattgaa tctctttaaa
    84301 tattaaaata ttataaccta catgtatatt ataaattaaa aagctatcta gttaaataag
    84361 aataaatttc atacataaaa attaatttat tcttatttaa aactacatag cctattttct
    84421 taaaatctct aaaaaactaa atcattgaaa taatcttagt atatctttat atgtgataaa
    84481 aagcataaat aacattaaag ctccaaaacc aacaacattt atcatgcctt ctttatttgg
    84541 gtcgagtttt ttaccacctc taacagcttc tagtaacagc ataagtattc tccatccatc
    84601 aagtgctggt attggtaata gatttactat acctaaattt aagcttatga cagctgctaa
    84661 atacactaca tttatgatgc ctgtacgagc agcatctgat accataccaa taacacctac
    84721 tggtcctgct acagcattgc caatccctcc tggtacacgt cctgtaatca tttgacctag
    84781 aaatgttagc atctgttttg tcatatctac agtagtttta catgcattta ctattgaccc
    84841 caaaaagtct ttttctcttt gtggttgaat ccctatttca tactttccat tgttattttt
    84901 aggtgttaca tttacaactt tatcacttcc atctctagtt atactaagtt ttaattctcc
    84961 accagaagaa gtgtttatta tatttgcaac ttcatcccaa gtcttaacag aattaccatt
    85021 aattttattt atcttatctc ctacttgaag ccctacagcc tgtgcaggag tatctggcat
    85081 tatctttcct aatttagtcg ttggagaacc tatatacaaa aatactggaa ctaaaagtat
    85141 tgctgctaat attatattga atattggccc tgctacaata gtactaaatc tttgtaatat
    85201 agacttgttt ccaaaagaat ttggacttat ttgttcttca tcttcacctt ccatgctgac
    85261 atatccacca attggaagtg ctcttataga atactctgta tcttttttta cactatatat
    85321 cttaggcccc atacctatag aaaactcatt tactttgata ccacttcttt ttgcaaatat
    85381 aaaatgtcct aactcatgta ttaatacaat tatactaaat agtattaatg cggctattat
    85441 agtcataaat tcaccttcct atttttttat cagatttgca acataagctc tactccatct
    85501 atctgtttct aagatttctt ctaatgttgg ttcacttata ctactatgaa cttctaaagt
    85561 cttctctatg taatatggta tgtcatagaa accaatttta tcctctaaaa attcacttac
    85621 taaaacttca tttgctgaat ttaaaacaga agaataagtt cctcccattt ttaaacactc
    85681 atatgccaat tttaaacatg gaaaagtttc taaatctggt tcttcaaaag ttaaagtact
    85741 aaattttgaa aaattcattc tttcaaagct actttccatt ctatctggat atgtaagagc
    85801 atactgtatt ggtagtctca tatctggaca tcctaattga gcaattattg agctatctgt
    85861 atactgcacc attgaatgaa ttatgctttg tgggtgaact actacatcta tattttcttg
    85921 ttctactcca aataaccatc tagcttctat cacttcaagt cctttattca taagcgttga
    85981 agaatcaata cttatttttc ttcccatact ccaatttgga tgcttcaaag cttcgttttt
    86041 agttatattt gcaagttctc cctttttctt tcctctaaat ggaccaccag atgctgtaag
    86101 tattatcttt tctatatttt ttttattttc tccatttaga cattgaaata tagcactatg
    86161 ttcactatca acaggaagaa tatttacatt gtatttttct gcttctttca ttacaagttc
    86221 accagcagtt accaacgttt ctttattcgc taatgctatg tctattccct tctttatagc
    86281 acaaagagtt gggactaatc ctatcatacc tactacagca gttaaaagga catccacttc
    86341 atcaagtgat gatattattt ttaatccttc cattcctgct aaaacttcta tttctatatt
    86401 tttaggcaac atttctttta attttaatgc tttattttcc tcaaaaactg ttacatattt
    86461 aggtttaaac tctactatct gttctagcaa taattcaata ttactgttag ctgatattgc
    86521 aactatctca aacttatctc tatgttctct aaccacatcc aaagtttgtt tacctataga
    86581 acctgtagaa cctaaaattg atatcttttt catataataa tcctttctaa taataaatat
    86641 accctgtcaa aacattataa cactactaaa acaattattt ttactattca tagaaatttc
    86701 atatattatt ccacagatta aaattaatct attatttttt gtattttgtg gaatattata
    86761 aaatattcta gtattattaa atgccctttt ttatttccac aacatcttct attttacagt
    86821 ctagtgctaa acatatcttc tccattgtat ccatagaaac agatttatca tttcctagtc
    86881 tgcctaaaac agaaatactt atacctgata tatttacaaa ttccattttc tttatttttc
    86941 tgtcaattaa caatttccat aatggagcgt atgaaatcat gttatcacct cgcaaaatat
    87001 attctatcac attttatcta ttttggaaaa ttttcatcta tttagataaa taattattta
    87061 tctaaataga tttcaattat agtttattaa atataaatat gttaaaataa aacaaaagca
    87121 taagttcaaa aattaaactt tatatatatt tatctcatta ttttactaaa acataactat
    87181 ataaaaaata tttactatta tatatctatt taaaacacat tattatagta tcatataaac
    87241 atatgtaaat atataattaa aaaagctaaa gattagtaaa tttataaaaa ttatattttg
    87301 aataaaagga gaaagaatgt tgtatttatt aaaaattaat caatttgaaa gaagctatga
    87361 tataggaatt tttaaaaatg aacaatcaat atataaattt attgaaaaaa taccctttgt
    87421 aaaaaaagat aatagtaatt ttaattatac aaattactat atggaatttg aagatattcc
    87481 tgaatattat gaagtaaatt tcaataatta tttatatatt attaccaggt tttcattcat
    87541 tccagatgga actgagatat tttttacttg ggaagaaatc cattgttggg atgaaaaagt
    87601 tgctaccgag aaaactttta taaatggcga aacattagtg gattcatata actttccaaa
    87661 taatgaagtg aaagactaca tacaaaagcg agaatcacta tatatagaaa caaaaaaata
    87721 ttatgaagaa aaaggattaa aaattgagag acatgcactc ggttcagaag atggtgaata
    87781 tgttgaactt acaaatgatt ctatacttta tttactagat atagaagcag ttgaaataag
    87841 agaacaatca aaaaatatag aagaatttct atataagtac aaaaaacgtt ttaaataatt
    87901 tatattttaa aatacataac aatacattga gtcatttaac gaaatataaa atgactcaat
    87961 gtatagacta ataaaaataa ttatattatt ttttagttac atatttgtta aaaaattctt
    88021 tttcttctat cggtttagaa aaataaaacc cttgtcctac atcacattta actgtattta
    88081 aaaattccaa gtctttttta gtttcaatac cttcacatac aacagacatg cctatacgat
    88141 gtgacatttc aataatacat tgaataatac tatatacttt ctcccggtta aaggtttctt
    88201 taagtaagct tttatctaac ttcaatccat taatagatag agaacataaa agacttaatg
    88261 aagagtatcc tgaaccaaaa tcatccattg aaattaaaaa tcctaacttt ttaagctcct
    88321 ctaaaatcga aataactggt tgagatattt cattaaaagc actttcagtt acctctatct
    88381 ctatatactt aaaaggaatt tcatattctt taacagtatc taaaaacctt tgataaaaac
    88441 tattttggta aatagtaacc cttgaaaaat taactgcaat cggatatgta tattgatttt
    88501 ttttcataaa cgtttttttt acaaatgaac acgctttttt taacatataa aagtccaatt
    88561 caataataaa tccacttttt tcaaacaatg gaataaattc atctggtgat aaaaaaccaa
    88621 gttctggaga aaaccatctt acaagagctt ctgcgctcac aacatttaaa gaagatattt
    88681 gaaatttagg ttgcaaatac atatgaaatt cttcattttc tatcgcttta tacatataat
    88741 tataaatact attttccatt tgtaactgtt ttaacagatt ttcattatac catactgtag
    88801 aagaaattcc tcttgtttta cttaccttgt gtgcaatatt tgccttatcc attatagaat
    88861 tgatagattt ataacctaaa ttatcaattt caactaagta agctcctata caataagata
    88921 tagtttgagt tacattcata tctaattcag agattatagc attagttagc atttcccgaa
    88981 tatcctctaa aagagaatct ctatattttg caagtattac aaaattatct gaacaaattc
    89041 ttgcacaagt ttcttttata ttaaaagttt tagaaagaac agttgcaact attattagaa
    89101 ctttatctcc atattcatat ccatgtgtat cattaatata tttaaaattg tcaatatcaa
    89161 tatttagcag tacatactct ttgttagatg cattgtgcaa aatttcaatc gctctgtttt
    89221 caaatgcaac ctgatttttt atttttgtta aattatcagt ataaaatatt cttttaaacc
    89281 tttttttatt ataatattcc caaattaaaa gacttattgt tgagaatata agataaataa
    89341 atagtgcagt agcaaaagaa tacaattttg cattagagtg tttttcagat ataaaaacaa
    89401 tttgattaga caacacagaa tactcttcac tcaatttata taatttatca cctgaagcac
    89461 catttctaac ttttataatt tctttcttca tagattccca catagaatcc atttgattta
    89521 gtttttgttg aaattcttta ttatcacatc tttgaaatcc attttctcca ttacctgttc
    89581 ttagctttat cagaatatta tccagtcgtt ttatcaagtc atcatttctt tcattattca
    89641 attcttgctt aacaaccttt tgagtttcac tgcgaatagt accagtgtga cttataattt
    89701 taatatgctc tatactgtga tatagagaaa atataaaaag aataataata actagccaaa
    89761 tagcagaata aattaaaaaa tcatattttt tcttcattat tgttacctca tttgtaatat
    89821 atataatttg caaataatca atctcttata aaaaatgatt atcaatattt tacagtgata
    89881 tgtatttatc ttaaatagtt taatcattta taccctataa attctacaaa ttcatcacct
    89941 ccaacacaaa cagcaatata cgtttttcta aaatttcttt ttaaacattc atcaacacta
    90001 tcattaaatc atttttaaat tgctcaatta atttactgca tcacttcttt tcttataaaa
    90061 tatcacccca ataatatatt tgtataatgt ctttatgtct ctttttaaat ttggcatata
    90121 cataatctat attttaataa ataattaaaa tactatttac ctacaattta actctttgaa
    90181 tttattttat catattatgt aaatatattc cttttttttg gtatattact taaattatat
    90241 ctatttttgt gcaataagac
//
LOCUS       DAFAZV010000015        83723 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFAZV010000015 DAFAZV010000000
VERSION     DAFAZV010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 83723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83723
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.015"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            186..2045
                     /locus_tag="KOU88_001530"
     CDS             186..2045
                     /locus_tag="KOU88_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3211430.1"
                     /translation="MKRFLRRIILVLFILLIFISFISIKLIHNVGDYGKLINYVGIVR
                     GASQRLTKLEMNHQPNDELIEYIDEILQELITGHGDYGLVITDCNEYNEDLLLLEKKW
                     EDLNIEIKKVRMKEQNNQLLSISEEFFSLANDTVFKIENFSKEKSNYLMTLIIIISII
                     GILACIILILQYSKKMVRLEKLNVDLKNIAYKDELTGVNTIEKFKLDANQNICIHKDK
                     KFAVFYIDFENFKYINDIFGYDYGDMILKRYANLMMNDIGKYEIFAREIADRFVALRC
                     YVDKEDLVVRQRDVDNELINITNEIKNKHSITVVSGICCIEDVNEKLSIDGLINRANF
                     AQKTVKNKPGTNYAFYNDSIRKKMIEENTIKSRIHEAIEKREFIVYLQPKVNLHSQKI
                     NCAEALVRWLTPDKGIISPAIFIPVLEKNFFIALVDKYVFEEVCKWIRKRLDENKPFV
                     QISVNVSRIQFYNTKFVETYSNIQNKYRIPKNTIEIEFTESVAFENQKHLLEIIHDLH
                     ENGFTCSLDDFGKGYSSLSVLKDLPFDVLKLDSMFFKASLDKDKEKIVIKNIVHMLKE
                     LNITTVAEGIECKEQVEFLRDIGCDLVQGFVFYKPMPILEFEKILDKEFVYNS"
     gene            complement(2319..2918)
                     /locus_tag="KOU88_001531"
     CDS             complement(2319..2918)
                     /locus_tag="KOU88_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBK3211431.1"
                     /translation="MAIELKKGQKINLTKKENSDLGEILVNLNWNQKVQKKGFFGSLR
                     SSNIDLDLGCLFEMKNGVKGAVQALGNAFGSLDNPPFAQLDGDDRTGSNTQGENLRIN
                     GNKIKDIKRILIYAFIYEGVANWSEADGIVTIKQKQDSDLVVKLDEHKNGYNMCSIAL
                     IENVNDETFSVEKVVKYFKGHREMDTEFHWGLKWVAGRK"
     gene            complement(3021..3818)
                     /locus_tag="KOU88_001532"
     CDS             complement(3021..3818)
                     /locus_tag="KOU88_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK3211432.1"
                     /translation="MKFKKLLCLLLCLVLTLAVVGCSKAKDDKKIVVGATLVPGGELL
                     EELKPLIKEKGYTLEVKNFDDYILPNEALNNGEIDANLFQHEPYLKEAVKAKGYKIMA
                     GKKLYVCPAILYSYKIKSVDEFKKGDTIAISNNPSSCSKNLRYLESIGLLTLPKGDGL
                     VSPKDIIENPKGIQFKELDIAQIPSSLPDVTAAFIDTTYAVPAGLDAKKNGIYTAPIN
                     DEYANLLAFRTEDKDSEKIKVLQDVLTSDKARSLIEEKYKGIVIPTF"
     regulatory      complement(3931..4036)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(4128..5114)
                     /locus_tag="KOU88_001533"
     CDS             complement(4128..5114)
                     /locus_tag="KOU88_001533"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBK3211433.1"
                     /translation="MLLIYNEKTNPYFNLAMEEYLLKNFDEDLFILWRNEPSIIVGKN
                     QNTLSEINLEYIKEYSIPVVRRQSGGGAVFHDLGNINFTFIACNNNNFSDFRRFTQPI
                     IDLLKTLDVNAEFSGRNDLLIDGKKFSGNAQYNYKNKVMHHGTLLFSSEINDLSKALK
                     VKPIKFEGKGIKSVKSRVTNISEHLHSKMDILEFKDAIMDYLSKTNTDNTNYCLSEHD
                     IKQIEKLTKSKYETWDWNFGNSPKYTLSNELKYSGGNVEFNLNVDKGIITSIKFFGDF
                     FGKCDVAFVENKLIGIRHEENALRNTLDSIEINDYFLGADTDILVSGILGVK"
     gene            5598..7328
                     /locus_tag="KOU88_001534"
     CDS             5598..7328
                     /locus_tag="KOU88_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HBK3211434.1"
                     /translation="MRNKKINIIFLTTIMFIMSTVMVFAEEDIDTIALANAEKFGILT
                     LIPPLVAIILAFITKNVIISLLIGILSGSFIIKASGINVFATFIQAFLDLVDRALVSL
                     ADPWNAGIILQVLAIGGVINLVAKMGGAKAIAEALAKRAKSAKGTQLITWFLGLLVFF
                     DDYANSLIVGPMMRPVADKMKISREKLAFIIDATAAPVAGLAIISTWIGLEVGLIHDA
                     FESISIDVDAFGIFLNTIPFRFYNILILAFIVISALLLKEFGPMRKAEIKSRSRKISI
                     DLDEGVEELDDLAPKNGVKLSVWNAIIPIGTLIIVALASFYYSGYTSIMGGDDKALIQ
                     LFTNSPYSFEAIKEAFSASDASRALFQSALVASLVAIIMAVVKKIFTISEAIDVWIDG
                     MKSLVITGVILILAWSLSSVIKELGTAKFLIHLLSGSLPPFLLPSLIFGLGAIISFAT
                     GTAYGTMGILMPLAIPLAYSLNPDMSYVIVSTSAVLTGAIFGDHCSPISDTTILSSMG
                     AGCNHIDHVNTQMPYAIFTAVITIVFGYIPAGLGLPIYIVLPVAIAAIFVGIQIIGKK
                     VDEAEIELVE"
     gene            7438..7518
                     /locus_tag="KOU88_001535"
     tRNA            7438..7518
                     /locus_tag="KOU88_001535"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:7472..7474,aa:Leu,seq:tag)
     gene            7853..8368
                     /locus_tag="KOU88_001536"
     CDS             7853..8368
                     /locus_tag="KOU88_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HXXEE domain-containing protein"
                     /protein_id="HBK3211435.1"
                     /translation="MEKYIWLFPLLFIFHDMEEIIGFGIWLKKNKSMLDKKYPFISKV
                     YENYSTEGMAFAVFEEFILCIIFCILTVITENQYVYLLWLGSFIAYTLHLVIHIGQSI
                     IIRKYIPSLITSIICLPISIWCISKSIYIVDCEMSTTILYSIIGIIIVALNLKFAQSL
                     IGKFTKWMSNI"
     regulatory      8860..8964
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            9174..11648
                     /gene="gcvPA"
                     /locus_tag="KOU88_001537"
     CDS             9174..11648
                     /gene="gcvPA"
                     /locus_tag="KOU88_001537"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HBK3211436.1"
                     /translation="MNELKRVSLYNIHKELGAKLVEFAGWEMPLEYEGINKEHEKVRK
                     SAGIFDVSHMGEVQIKGAESEKFIQNLVTNDISALKINDIIYTPMCYENGGVVDDLLI
                     YKFGEEDYLLVINAGNIDKDVAWIIKQSEGYNVDIKNISSEVSQLAIQGPKAEEILQK
                     ITDIDLNSIKFYKSIPSTKVCGCPCLVSRTGYTGEDGFEIYCKNKYVEIIWNEVLKVG
                     GEDICPAGLGCRDTLRFEAALPLYGHEINEHISPIEGGLSIFVKTNKESFIGKSILSK
                     EKESGAKRKLVGFEMQGKGMPRNGYDIRIGDKTVGFVTTGCASPTTGKILGMGIIDSE
                     YAKVGNEIGIAIRKKVVPAVIVKKPFYKKQYKKDNIILNKENKFSYIPATSEDKSKML
                     KVVGLNSVDELFSDIPEEVKLKRDLNLEIGKSELEVSKIVKRLSEENLSLEDLTCFLG
                     AGAYDHYIPSIIKHITSRSEFYTAYTPYQAEISQGTLQVVFEFQSMIAEITGMEIANA
                     SMYDGATAAIEACIMAMNQTRKSKIVVSKTIHPETLSILRTYLQYKDCEIVEIDFCNE
                     YGTTDIEKLKASVDKDTACVLIQTPNFFGIIEEMEEIEKITHENKAMLIMSVDPISLG
                     VLKTPGEIGADIVVGEAQSLGNPLNFGGPYVGFLASKSKYTRKMPGRIVGQSLDVEGK
                     IAYVLTLQTREQHVRREKATSNICSNQALNALVASIYIATMGKEGFKEVGMQSMKKAH
                     YTYNKLVQTGKYKPIFKGKFFKEFAVQGNLNIETINDKLLEENILGGYNLEYNYPELK
                     NSTLLCVTEKRSKEEIDKLVGIMEGL"
     gene            11648..13105
                     /gene="gcvPB"
                     /locus_tag="KOU88_001538"
     CDS             11648..13105
                     /gene="gcvPB"
                     /locus_tag="KOU88_001538"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HBK3211437.1"
                     /translation="MKEYNSLLIDISKKGRKAYSLPKLDIDDIKIENMIDQDMARQSE
                     LNLPEVGELELVRHYTLLSNKNFGVDTGFYPLGSCTMKYNPKINEDMAALPNFTGMHP
                     YQSSDTAQGSLSLMYDLSRRLAEITGMDEVTLQPSAGSHGEFTGLMIIKAYHENRGDH
                     KRTKVIIPDSAHGTNPASAAMANFDVIQIASDKNGAVDINALKEVLNDEVAALMLTNP
                     STLGLFEKNIKEIATLVHEAGGLLYYDGANMNAIMGITRPGDMGFDVVHLNLHKTFST
                     PHGGGGPGAGPVGVKKELVPFLPIPVIERKEDKYVLNYDREKSIGKIKNFYGNFGVLV
                     RAYTYILTMGRDGLKEASEMAVLNANYIKESIKDDYILPIDTLCKHEFVLGGLPRGEA
                     NIKTIDIAKRLLDYGYHPPTMYFPLIINEALMIEPTESESIETLDSFIEAMKSVAKEA
                     KEEPELLKTAPHNTLVKRVDDARAVKKPILTWSQR"
     gene            13528..15885
                     /locus_tag="KOU88_001539"
     CDS             13528..15885
                     /locus_tag="KOU88_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBK3211438.1"
                     /translation="MDKVNLERYSCDINVGLNKNQLQSRIDDNLINAFDNGKTKTYKQ
                     IFKDNIFTLFNLINIVLVCLLVSVGSFKNTLFIFIAVINTIIGVIQEIRAKRLLDNLS
                     VIVSNKVSVIREKEKKEIDVQELVLDDIMILKTGNQICADSKVLNGKLEVNESLVTGE
                     SDIIIKNKGDFLYSGSFVVSGEAFVRVENIGKDNYANKIANDAKISKKHNSQLRNSLN
                     AILKIVGIIIIPLGIILFAKQHFGNGDSIATSVVGTVAAVNGMIPEGLTLLTSIALAV
                     GTIKLASHKTLVQELYCVETLARVDTLCLDKTGTITEGKMQVDDIVMLEEVDINEIMG
                     NICNSLKDDNATLNAIRDKYNVLDTYKAKNLIPFSSERKYSGVTFENKGTYLLGAFEF
                     IFKEKNKKLRIEVERYSKKGNRVIVLAHSDSYMEDNNIPEDIKPLAFILILDKIRDEA
                     KETLEFFYNEGVDIKIISGDNPITVSEVARKAGLKTASNFIDATTLKNDSDIYKAVDK
                     YSVFGRVSPQQKKQMILALKKQNHTVAMTGDGVNDVLALKEADCSIAMASGSDVTKNV
                     SNLVLLDSNFASMPKVVMEGRKVINNIQRASSLFLVKTIFSFFLSLLTLFFFSRQYPF
                     VPIQLSLIGAVTVGIPSFFLALEANKSRISGNFLLNILKNALPGALCVTVNVIIVYNI
                     VEYLGYSSSVFSTMCAILTGVCGLLILRQQCLPFNKERLFLIVSMTIAFVIGILFLGG
                     LFSFVALSRELILITMALAILMPIMIKVMLFVLDEILETIVPDLN"
     gene            complement(15971..16288)
                     /locus_tag="KOU88_001540"
     CDS             complement(15971..16288)
                     /locus_tag="KOU88_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBK3211439.1"
                     /translation="MSEFKNITAVKKANVYFDGKVSSRVIILPNGERKTLGLMLPGEY
                     TFSTREEEIMEMLAGSMDVKLPGSNEFVTYKEGQKFNVPSDSSFDLKVNEVVDYCCSY
                     IAD"
     gene            complement(16872..18143)
                     /locus_tag="KOU88_001541"
     CDS             complement(16872..18143)
                     /locus_tag="KOU88_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBK3211440.1"
                     /translation="MLKVLKGNIIFTKTSETFTVFENSYIMLEKGKVKGIFKEIPKEY
                     KNLKVVDYTDKLIIPGMNDLHAHASQFKNLGMAMDKELLPWLETYTFPEESNYKDIEY
                     ATKMYKKFVKELWKSGTTRIAVFATVHKEASMKLMDIFKEVGLGAYVGKVNMNMNCPD
                     TLLENTQDSITDTEEIINKYSDTDSIVKPIITPRFIPSCTSELLKGLGDLCLKYNIPI
                     QSHLSENYDEIEWVRSLEPESKFYGDAYNRYNLFGQTPTLMAHCVHCSQDEIDLMREN
                     NVMAVHCPASNFNVGSGAMPIRKLIDNNIRLALGSDISGGHTLSIFKAMVSAIQLSKL
                     YWVNSGKKYNFLSLSEAFYIATKSGGSFFGKVGSFEEGYDFDALIIDDSNLNHDNYSI
                     LERLERFIYVGDDRNIIHRYVCGKLIEEPNI"
     repeat_region   18790..20126
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=18790..18818
                     /rpt_unit_seq="gttttatattaactaagtggtatgtaaat"
     gene            complement(21361..21912)
                     /locus_tag="KOU88_001542"
     CDS             complement(21361..21912)
                     /locus_tag="KOU88_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211441.1"
                     /translation="MSINTVIAKNLNRLRNERNLSLGQLAELSGVSKVMLSQIEKGDS
                     NPTVNTIWKIASGLNVPYTAILEQPQNETFIVSKTDIDVQVSENKDYRLYCYYPNTPT
                     RNFELFQMELEEGHSYTSVGHSEKSQEYIMIIEGQLKLEVNDSIYQLRENDSICFSAE
                     SIHTYHNQGEKTLKAVIINYYPV"
     gene            22103..23065
                     /locus_tag="KOU88_001543"
     CDS             22103..23065
                     /locus_tag="KOU88_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBK3211442.1"
                     /translation="MRVLNNVTEAIGNTHMLHLSKIADEFGVQGNIYAKMEYLNPGFS
                     KKDRVALQMITEAENAGLLVPGQAVVELTSGNTGTGLAIACACKGYKFIACMSKGNSM
                     ERARMMKALGAEVVLVDQMPNSVHGQVSGEDLALVEIEAQKIAKERNAFRADQFNLEA
                     CNHAHEKYTAEEMWEQLDGNIDVFVDFLGSGSTFAGCSKTLKKHNSSIKCYVVEPETA
                     AIYSGKEITDQGHKIQGGGYSMDLPLVDKKLIDGYIQVTDEEATDVARKLAKLEGVFA
                     GFSSGANVCAAIKLLKSSEKGKNIVLTLNDSGLKYLSTDLYEEL"
     gene            23360..25204
                     /locus_tag="KOU88_001544"
     CDS             23360..25204
                     /locus_tag="KOU88_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBK3211443.1"
                     /translation="MQKRILRNFIFTGKNILSKLVFIIKYNFSTLILFELFHKGLALF
                     FIWPSIRYIFDILIKSLHIVYLNMDNFIKVLTNPMSIVLIILSVIILAFYAFFEFTSV
                     IICFNKSIKYEKIGLFELFKISFENSIKLLYPKNILLFIFVILIIPLVNTVLISGFIG
                     KIQIPEYILDYIKSDIILNIIYMIFLLIIYISVIRWIFSIHEITLNTENFKRARKESV
                     NLIKGKIIRTIIYSLILSLVVAIIGYAIYYSGIIFIGIWTKYCTDMEFLKNVFINRCI
                     AFEEYFRLILSIFIFILDIGFISATYYQYKGVSISKNNIKKEKKSISKIVFNLVLILL
                     ISYIESVAFSSHINGMFNTSFSFYTTAIAHRAGAEMAPENTLAAIEEASHAKADYAEI
                     DVQETKDGELIVLHDSNFKRTTGVDKNVWDVNYNEVKTYDAGSFYYYGKGYYDEKFVG
                     EKIPTLKEMIKYSKGKVKLLIEIKLNGHEKGDVVKKVVQLIKENNFENQCIVASMDKT
                     ILQKVKKLDENLLTCYFMAIAYGDFSKLNYVDIYGIESTFVNKTVVEKIHKMNKKIFV
                     WTVNSDSLIEKMLDLNVDSIITDNPYLIESAIYWKKNGFISQVSDYLF"
     gene            25526..26110
                     /locus_tag="KOU88_001545"
     CDS             25526..26110
                     /locus_tag="KOU88_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBK3211444.1"
                     /translation="MTEREKMLAGELYDCGDIELLTQWHKAKDLVRDYNQTDSSDLEK
                     KEKILNELLGGKGKNLWITAPYYVDYGNNIYFGNNCEVNMNCTFLDDNKIIIGDNALI
                     APNVQIYTAFHPTNAGDRFGNAKEDGSFEFCKTQTAPVTIGDNVWIGGGAIIMPGVTI
                     GDNVVIGAGSIVTKDIPSNMIAYGNPCRIIRENK"
     gene            complement(27212..27388)
                     /locus_tag="KOU88_001546"
     CDS             complement(27212..27388)
                     /locus_tag="KOU88_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211445.1"
                     /translation="MFIGEIDKCTHILTAYISSSYDYCNFLDTQLDDFISEYGETVVE
                     TCLHQVLLLVSRYN"
     gene            27963..28985
                     /locus_tag="KOU88_001547"
     CDS             27963..28985
                     /locus_tag="KOU88_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211446.1"
                     /translation="MVNWEIKKLAKSKSMFISLGILVLILMISIFITPVLETESYYID
                     KEKGRIEDTRSGIDIGNEKFQNKINVLKQFSNQTDTGEFSKKIELMSKKKLDNLSVNE
                     YKDISFWKVFNYRVTNSLINVGMLIIISIIISNIYVDEVVTSVKDIILSSKEKKKALK
                     SKIFVALLVPLVIYSVYLMGIFIITCMQQGVPVNGDLESFRIVDNVVALKTNLSITKY
                     VILNIGIELLMFEGWAMIAIFGSFISKSSISSISFFIFIISITKIMSVIHILPKKLLS
                     VVSNVNYYDLIFGFNKIIGNYLGDIMIFKVNIDIVNIAIGLLMAILIGAMSLCFLVIK
                     SDYISR"
     gene            28999..29886
                     /locus_tag="KOU88_001548"
     CDS             28999..29886
                     /locus_tag="KOU88_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211447.1"
                     /translation="MNKLEIENLSKIYGKKVANDKITVTLENGVYGLLGPNGAGKSTL
                     MKQITTLIKPDEGQILYNGEDIFKMDADYRNILGYLPQEFGVYKNFTAKEFLQYIGAL
                     KGLRGKYLNSKIGELLDLVGLYDVRNKSIGKFSGGMKRRVGIAQVLLNDPKIIVLDEP
                     TAGLDPQERARFRNLIAKMSRDKIIILSTHIISDIESVAKETIMIKDGKLLMKGTHKD
                     ILSHMENKVYNVQVKNECEVDDIQSKYKVVSIQSDIDSVVLRIVSEDIPSGDNIQSVQ
                     AKFEDVYMFYFDLEDAREV"
     gene            29892..30665
                     /locus_tag="KOU88_001549"
     CDS             29892..30665
                     /locus_tag="KOU88_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211448.1"
                     /translation="MMYLVKAEMIKILKSKSVWIIWLFLIFFGFFLIRKFDVLDTYAD
                     IFYKIEGSIPLIGLIMFIITSGNYIKEYDSNMTGLINTTKKGKKSVVLSKLVANGLIL
                     SIINISFILLVGIRGFSFFDFKNLNESIHNLWYFGNSNLNLTVIQMYIIVILTTIFAS
                     FIFAQIGLTLSSIFKSAVIPFILGGLIMAIPYFSVGFIPDKAIKFMSVTPNWIMMSQQ
                     MVKYNVPSILIVFSIVISIILMIVLTKITYENFTSSKRF"
     gene            30777..31502
                     /locus_tag="KOU88_001550"
     CDS             30777..31502
                     /locus_tag="KOU88_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012450879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3211449.1"
                     /translation="MENRVLIIDDEVEILKLLETVLKKEGLNNIYTAKTKKEGLELFK
                     SINPDLIVLDIMLPDGEGYDICKEIRKTSNSPIIFLSAKTEELDKLLGLAIGGDDYVT
                     KPFSPKEVAFRVKAHLRRLSYFSDAQNESKNLNNNEEKIISFGPYILNESRAELIKDG
                     KSIGLSAKELKILSLFAHNQNQIISKEKLWDKVWGEDYVGFDNTIMVHIRKVREKLED
                     NPSKPEYILTIKGLGYKLAVKED"
     gene            31506..32909
                     /locus_tag="KOU88_001551"
     CDS             31506..32909
                     /locus_tag="KOU88_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3211450.1"
                     /translation="MKWKITRNFIFTIVFVAISVVIINIISILYVISTNSFFKVVDSG
                     NTPEEFARSFEKDLYEKDGEFKLSKIGAEKLEKSNSWIQVLNDLGEEVYGVNVPKDTP
                     KKYTPFQMVNNYKYIETKYVNFVLEKYLNKKHLNIIVGIPSRDISRIILTYSQNNIKK
                     TLNKVIIITLVIDSVVALGVGYLFSRKLTKPISSVLWSIETMANGNYSLYLKDRGIYE
                     EVFKNINMLADTLRVNEVERKENEELREEWLANITHDIKTPLASIQGYAEIINDKDYE
                     FEEDEIQEYTEIIYNKSKYIKDLVDDLNLSTRLKNNTIVLDKKKINLVSLVRDIIIDI
                     LNDNRYKNRNIEFESNEDLIEVYVDSILFRRAITNLIFNSIVHNSEGTLISVEIVKKD
                     NIEIIIKDNGIGISKSDLKHIFKKYYRGTNTGEMHKGSGLGMAISKEIIEIHKGKIYV
                     SSEIGIGTKIIIEIKQN"
     gene            32920..33744
                     /locus_tag="KOU88_001552"
     CDS             32920..33744
                     /locus_tag="KOU88_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraX"
                     /protein_id="HBK3211451.1"
                     /translation="MDFLKKGISGFTIKILALIFMTFDHIAVFMPQTMQIPIWFHWVG
                     RISAPLFIFMAVEGFYHTSNRKKYISRLYIWSVIMAIGNQIINNVFSHPEGAIIINNI
                     FSTLFLIAIYLQAIEFIKKFRKEKEIKYFIIGLLMIIIPIILGIFTVALLFKVTNRVI
                     ALFMILVPVPFLVEGGPIWIILGIIFYLCRGKKFSLSICYVLMCIFIFTTMSNGDYSL
                     KNSILQNYQWMMIASLPLMLLYNGEKGKSMKYLFYLYYPIHVYILYILGIYLINGF"
     gene            complement(34069..34689)
                     /locus_tag="KOU88_001553"
     CDS             complement(34069..34689)
                     /locus_tag="KOU88_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3211452.1"
                     /translation="MKVLLINGSPNQYGCTYTALNEITKVLSKHDIKTEILYLGKETI
                     PGCISCASCFETGKCIRNDKVNELIEDLDNIDGIIIGSPVYFSSATGQLTSFLDRLFF
                     IAGSRMATKLGASVVSCRRGGASATFDQLNKYFSISNMPIVSSQYWNQVHGFTPEDVM
                     KDEEGLQTMRTLGENMAWLLKCISAGKKAGIKEPQYEETIMTNFIK"
     gene            34954..35286
                     /locus_tag="KOU88_001554"
     CDS             34954..35286
                     /locus_tag="KOU88_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211453.1"
                     /translation="MSIDCISNTDLSETGFSYTLSLISGKYKMIILYCLVEFEVVRYN
                     ALKRYINTISYKTLSLSLKELEADNLIIRTEYPQIPPKVEYSLSERGKSLIPILDAMC
                     EWGERNRP"
     gene            complement(35406..36047)
                     /gene="pcp"
                     /locus_tag="KOU88_001555"
     CDS             complement(35406..36047)
                     /gene="pcp"
                     /locus_tag="KOU88_001555"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBK3211454.1"
                     /translation="MKILLTGFDPFGGEPINPAQEAVERVNNNINGAEIIKITIPTVM
                     TKSVEAIDKAIQEHNPDIVISVGQAGGRFDITPERVAINIDDFRIKDNEGNQVIDTII
                     KEDGEPAYFSKLPVKAMVKHMNENKIPASVSNTAGTFVCNHVMYGILYMIDKKYPNIR
                     GGFIHIPYTTSQVIDKKNTPFMSLEEIVKGLELAIEACIIYKEDVKEIGGEIS"
     gene            complement(36068..37000)
                     /locus_tag="KOU88_001556"
     CDS             complement(36068..37000)
                     /locus_tag="KOU88_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBK3211455.1"
                     /translation="MQNFINISLEIFYALMGFLMIVIAYKSFTTINNNKKYGTSLFWI
                     LISLPFIFGRLIPANIIGIILILSSLLTLSKQVVFAKYEEPDENFGKEQADKLKNKIF
                     IPSLILAFAAVVVAMSLSNFDNSSQFAIGVGSIIALISALIITKAKPATSVQDGSRLL
                     QQMGPASMLPQLLVALGALFTQAGVGEVISTMISGVVPADSRLFGVIAYVLGMVIFTM
                     IMGNAFAAFSVITAGIGIPFVLSQGGNPAIIGALALTAGYCGTLLTPMAANFNIVPAA
                     LLECKNDYIVIKYQAPVALVLIIAHILVMYFLGF"
     gene            complement(37022..37687)
                     /locus_tag="KOU88_001557"
     CDS             complement(37022..37687)
                     /locus_tag="KOU88_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBK3211456.1"
                     /translation="MIKLIGILIVVIGFILKIDTLFTVLLAGVATGIVAGLDFNQIFT
                     ILGDSFVSNRGVSLFILTLPVIGVLERYGLKQRAVSLIEKLKRLTTGKVLTIYMIARQ
                     IAGALSIRMSGHPQFVRPLVNPMAQAAGLSNSDELKESDEEAIKALSAASENYGNFYG
                     QNLFAGSSGVLLIASTLTQFGYNVTGLNIVKASTIMAVIALVVATIQFTLYDKKLNKS
                     HKK"
     gene            complement(38234..38707)
                     /locus_tag="KOU88_001558"
     CDS             complement(38234..38707)
                     /locus_tag="KOU88_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBK3211457.1"
                     /translation="MNTIIIYSSKYGCTKDCANILKNKLSDNVTIVDINNNNKIELSK
                     FDKIIIGSSIYVGSVSKKIQVLCNDNVELLNKKQVGIFLCCGFSEQADKYLKSNFPSS
                     LLESANAIGIFGSEARLEKMKFLDKLIMKAVSKGNYDSFRISQDNIDNFLINLNS"
     gene            complement(38710..39114)
                     /locus_tag="KOU88_001559"
     CDS             complement(38710..39114)
                     /locus_tag="KOU88_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBK3211458.1"
                     /translation="MKIRNKATNKKKKYVKISIALFFVFICIIIVIVSNLKPENLVVK
                     DIDINNVKNGIYTGSADNNLVKATVSVEVNNGKIQNINILKHDHLLGKPAEKITTSII
                     KQQSLDVDAITSATYSSNTIRKVVENALRKGE"
     gene            complement(39089..39718)
                     /locus_tag="KOU88_001560"
     CDS             complement(39089..39718)
                     /locus_tag="KOU88_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3211459.1"
                     /translation="MSIKERRKNEKEEMKKKIMDASIEIINQHGYENLSIRKIATKIE
                     YSPTTIYLYYKDKAEIISDMTNKLYNTVESNAIDIMNNCSSLPIDKQIIEIMTSFIKT
                     LSSEPEMAKAIMHSRMNIIFASENTNNTPSNNGIKMLDKFLSIGIEQGIFKKNIDKSS
                     WMLISALLGFVLCVVENKLYSLHNFSQLIENFLDILVGGLYNENSQQGY"
     regulatory      40083..40126
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            40227..41195
                     /locus_tag="KOU88_001561"
     CDS             40227..41195
                     /locus_tag="KOU88_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HBK3211460.1"
                     /translation="MEKRKVIIDCDPGIDDSLAILLALNSPELEVIGITTCCGNVPAN
                     IGAENALKTLQMCSSLNIPVYIGEEAPLKRKLVTAQDTHGEDGIGENFYQKVVGAKAK
                     NGAVDFIINTLHNHEKVSIIALAPLTNIAKALIKDKKAFENLDEFVSMGGAFRIHGNC
                     SPVAEFNYWVDPHGADYVYKNLSKKIHMVGLDVTRKIVLTPNIIEFINRLDKKMAKYI
                     TEITRFYIDFHWEQEGIIGCVINDPLAVAYFIDRSICKGFESYVEVVEDGIAMGQSIV
                     DSFNFYKKNPNAIVLNEVDEKKFMYMFLKRLFKGYEDIIDSVEGVI"
     gene            41197..41760
                     /locus_tag="KOU88_001562"
     CDS             41197..41760
                     /locus_tag="KOU88_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK3211461.1"
                     /translation="MKRKICVKTITLIAFGISINIIGAFIAMGLRLPVYLDSIGTIMI
                     ASLLGPKYAVVTGVFGSLISGITFDVYSLYFAPVQISTGLLAGIAFKKNFLRGLKTPI
                     GVLLFAIPTSIISSIISAFLFGGMTSSGSSYIVQILKVLGLGDVFSVFVTQVFTDYGD
                     KLLAVVLVNLGLNAVPKTLKVSLTGGK"
     gene            41768..42457
                     /locus_tag="KOU88_001563"
     CDS             41768..42457
                     /locus_tag="KOU88_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3211462.1"
                     /translation="MDRYSEITNKNQREIVLLKGFPCIWGKCSFCDYIDDNSNLEEEM
                     NKLNLKVLKNVTGKYGVLEVINSGSCFELPKDTLEKIKCIIKEKNIKKLFLESHWSYK
                     NRLKEMREYFEIPVVFKIGVETFDNYFRNNILNKNANFKTPQDVKEYFDSPCIMVGIK
                     GQTKDMIDKDIEIILNTFEKATVNVFINNSSSIKRDEELVKWFVSKYKFLDENPNIEV
                     LYNNTDFGVGD"
     gene            42584..43312
                     /locus_tag="KOU88_001564"
     CDS             42584..43312
                     /locus_tag="KOU88_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBK3211463.1"
                     /translation="MMFDRGKWNKLDYNELLEYMMSIQDIKYRDFNKKLIPGTENIIG
                     IRVPNLRKLSKEISQGNWKEFLEVAEDTYYEEVRLQGMVIGNINSNFEETLYYVKRFI
                     PKIDNWSVCDGFCSDLKSMKKYKENMYDILKKYVYSKNPWEIRFALVMFLIYYVDDKH
                     IKEIFEYCNNIQSEEYYVKMGMAWLLSICFIKCEEETFLYIKNNNLDDFTYNKMLQKI
                     IESNRVDLEKKNIIRSMKRKTRRC"
     gene            43326..44000
                     /locus_tag="KOU88_001565"
     CDS             43326..44000
                     /locus_tag="KOU88_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBK3211464.1"
                     /translation="MNNNEDRIDKFLELQSKGFKFAEIAQNLKISQSTLRTFLNKKGY
                     KSEKGKYILKDELNYNKSLDNRNLEEEKAKEYEKSKKNTISNRKKVSTKKKISNEKAL
                     SKSVEQIEFNDTGLKNAKPKQNVKPKKDRKINITQEDLDKLCEVYDWYLEVKDYNIKP
                     KKVSNKKDVHIDDEHIDELKTTRIRIDKEIWNDFERLCSNSNFEKHQILTQALKEFMK
                     KYKNLL"
     gene            44026..44862
                     /locus_tag="KOU88_001566"
     CDS             44026..44862
                     /locus_tag="KOU88_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211465.1"
                     /translation="MNKIVKKSISLMIILTIFIFMLTACEKDEQPDSVDIQTEDKNEI
                     KIDEGNAKVLNIGKSEIINIDEGDKVDTSTKVENNSTFNISNVELIYNEYDENKKIIS
                     SDSKALLDMTLMPGKVAYIECGHKTFVKGVEVYAYEYEAEGKIVYVNLKENTINIRNN
                     NIKLENSSQYEVLSTSELKKVNESNEGITYQVKVKNSSSKDLGNIILKTAEVNENGEY
                     LTVNRVPSYKILKPSEETDIDILCSTKAKSVEIVGYTYDDIKEKANVDIDLKSHKVKI
                     DK"
     gene            44878..45549
                     /locus_tag="KOU88_001567"
     CDS             44878..45549
                     /locus_tag="KOU88_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3211466.1"
                     /translation="MKVLIVEDNKILLESVVEELSKHFETEKCEDGEEALYLVNQNIY
                     DLVILDLMLPNINGFDILKKMRVNNIDTPVLILTAKETLDDKVEAFTIGANDYLTKPF
                     YMEELVARVYAILRTNGKIKERNGLEFKSLYLDTLEKRVYIEKEEIKLQNKQFNLLEY
                     FVLNKGSILLKEQIYDRIWGIDSDATIEIVEVYVSNLRKKLSKYGYDKYIKTKRKVGY
                     IFDDK"
     gene            45539..46771
                     /locus_tag="KOU88_001568"
     CDS             45539..46771
                     /locus_tag="KOU88_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3211467.1"
                     /translation="MINKNVFTSTKNHLIKMYIIVVGSFLIIFSIFIYSYFRGLTYSG
                     IDSEINDELEYIVSQFKRTSFLNPIRLKDPKDMVYVYEDGRISYYTQNEYFDELLPDR
                     RLDKKNSFFKYTENGYTFRELNVDVGRYQIQIIRNIDSEMNSLRQLTSVLIIGILISV
                     IITYFVAVYLTRKALIPIETAWKNQAKFIQDASHELRTPITIVSSKLESMLKSPESTV
                     NDEVETIATAMKETRRLKKMITDLLSLTKEDSIVKVNLEEIDLEKLLEEISEDYIDIA
                     EFQEKRFVFNSKLKNKVIITDKNKLRQLILIFIDNAFKYTKLGDEIALELKEDIEDEV
                     TLLISDTGIGIKKEEIPLIFDRFFRSENVRNKDLEGSGIGLSIARMISLNLSIDINVT
                     SDVDIGTTFELSIPKKLK"
     gene            46921..47238
                     /gene="trxA"
                     /locus_tag="KOU88_001569"
     CDS             46921..47238
                     /gene="trxA"
                     /locus_tag="KOU88_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBK3211468.1"
                     /translation="MAKVINTSEFRSSVEGSKGVVVVDFFATWCGPCNMLGPVFAELG
                     EEMKDKARFVKVDIDESLEIAQQFNVSTVPTMIIFKDGKPVETLIGFMPKNKIEMQVK
                     SYL"
     gene            47255..48133
                     /locus_tag="KOU88_001570"
     CDS             47255..48133
                     /locus_tag="KOU88_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK3211469.1"
                     /translation="MRYDIAIIGSGPAGLSAAINAKIRNKTIIMFGNDNLSNKLVKAP
                     SIDNYLGFYDISGDELKDKFKSHIDSMDISIENKRINNIYAMGEYFTIMSGNDMYEAT
                     TVILATGVEYTRPIKGEEEFLGRGVGYCATCDAPLYRNKKVAVIGYNEESKEEANFLS
                     ELTSKTYFIPMYKKDNLMRSSDNLDDSIEVIHDRPVQIDGDKLVNKVSFKENHIEVDG
                     VFVIKDSTAPSALVPGIEIDGIHIKVDNNMKTSIDGCFAAGDCVGKPYSYIKAAGQGQ
                     IAALNAVYYLDKLKRA"
     gene            48403..48771
                     /locus_tag="KOU88_001571"
     CDS             48403..48771
                     /locus_tag="KOU88_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK3211470.1"
                     /translation="MENLVKIFKALSDETRLNILILVSKRNICQKGISKYLGISDSAV
                     SQHIKILKDVGIITGYKEGYYVLYHINKESFNICVDFINSMLSNSSESFIDVFDVNTI
                     HLGCSKECKSIKKCCKRREK"
     gene            48774..49145
                     /locus_tag="KOU88_001572"
     CDS             48774..49145
                     /locus_tag="KOU88_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifB/NifX family molybdenum-iron cluster-binding
                     protein"
                     /protein_id="HBK3211471.1"
                     /translation="MKVCIPVEENKGLDSKPYGHFGSAPIFVVCDLESGEVKSLDNGD
                     LDHEHGKCQPLKALSGTAVDAVVVGGIGQGAIIKLNGMGIKVYRAEGDTISANLDLLK
                     NGKLVEFPSDHTCSHDGCGHH"
     gene            complement(49289..49744)
                     /locus_tag="KOU88_001573"
     CDS             complement(49289..49744)
                     /locus_tag="KOU88_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211472.1"
                     /translation="MNINTVQGDSIEVLLRQLGATRISKVSSTLYFIKFDLGDGWEIS
                     YTYNINAKDQYFLQRIEPYPIGRGLFNDEYEIVSFISKDLKKFLNAKNSSNFKTFVEV
                     TRKVNSIIDNVEELFLNYNVDGDDLKTLNKELNDILNDIDYIEKHTKKI"
     gene            complement(49783..51048)
                     /locus_tag="KOU88_001574"
     CDS             complement(49783..51048)
                     /locus_tag="KOU88_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsB/NhaD family transporter"
                     /protein_id="HBK3211473.1"
                     /translation="MEFQQIIAICIFLIVMAAIITEKVNRSVAAVGGALLMIIFNILT
                     LDEGLSHIDFNTIGVLVGMMLFVAVVKNSGLFEYIAIWTAKKAKGDPWKIMICFAIIT
                     AILSAVLDNVTTVLLIGPMTIVITQILGLNPVPFLITQILASNIGGTATLIGDPPNIM
                     IGSAANLSFMDFVINLGPAVMVILAITIICFRFIYGKELVVNERAKNAILKLDEKKSV
                     KDKPLLIKSLILIAFILFGFMFHSTIHIDSSVVALTGASIMLLIGKQDVDEIMAGIEW
                     STILFFMGLFVVVGGLVEVGIINKLAQALIGLTEGHLVFTMLLILWLSAIVSSFLDNI
                     PFVATLIPLILTMQAEGIDVMPLWWATSLGACLGGNGTLIGASANVVLAGIGNKHGHP
                     ISFKEYFKIGFPLMIISIIISTVYLIIKF"
     gene            51518..52969
                     /locus_tag="KOU88_001575"
     CDS             51518..52969
                     /locus_tag="KOU88_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBK3211474.1"
                     /translation="MDFFNGILTSINNAVVFVNNYLWSYILIIMLVVIGIYFTIKTNF
                     VQFRYFIEMFRLLGDGTANKNAKKEGKISSFQAFCISTSSRVGTGNIAGIAIAVVAGG
                     PGAVFWMWLIALIGSASSFVESTLAQIYKVKDGQAFRGGPAYYMEQGLNKKWMGILFS
                     ILITICYGFVFNAVQANTVSLAFNNAFGISKMAMGIGLGILTAIVIFGGVHRVAKVSE
                     IIVPVFAGLYILVALAIVVMNITEIPSVIALIVESAFDFKGMAIGTFMGVVMTGVKRG
                     LFSNEAGMGSAPNAAATAHVTHPVKQGLIQSLGVFTDTIIICSCTAFMVLLYSGYSSS
                     GATGIELAQEALTHHIGPVGNIFIAVCIFLFAFSSIVGNYYYGESNMEFMSGSKTKLN
                     VFRVFVVGMVLFGSLTQVDVVWNLADLFMALMAIINLIAIALLGKYAFIALKDYTSQK
                     KSGIKDPVFIADEIEGLEKVSEWHRELSEEHLG"
     gene            complement(53167..53808)
                     /locus_tag="KOU88_001576"
     CDS             complement(53167..53808)
                     /locus_tag="KOU88_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007491147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBK3211475.1"
                     /translation="MTDNYIFDSYNNLVDGLSAYLGEGYEFILYKFNGVHYSINKIAN
                     GKYNTVKEGDIITDFDLALINKLENDADGDFISYFNRNKLGEPLKSTDIVIRGVDNKI
                     IGLLCIHFYLNTPLTRIIGSYIPEHNAMQSAPVLENIVEDTDEVILKSYQDAKVIVEN
                     DSNISSNDKNKSIVSILNESGIFKIKDSVVKVADLMGLSKNTIYMHLRNLNKN"
     gene            54282..55661
                     /locus_tag="KOU88_001577"
     CDS             54282..55661
                     /locus_tag="KOU88_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016290023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK3211476.1"
                     /translation="MAQDKIVVEILENIGGKENIKEVAHCMTRLRIKVCDSSQVNQEK
                     LKKIKGVLGLVLKGEQYQIVIGPNVSQVYNTLNEVIGIIPEKDSKKTISEGKQNSIAK
                     ILDTIAGIFNPIVPALAGAGLIKAILALLVASKFLSADSETYIILNTISDGVFSFLPF
                     MLAYSAAKIFKMNTYVAVAIAGAMLHPNFTNLIQQGLTKISFIGIPMSLIQYNGSVFP
                     IVLTIWFASYIEKGVDKITPKALKIILVPALTILFAAPIALIIIGPIAQMLGNYIAGG
                     ASILFERGGIFAGLIYGGIYSFMVVTGLHHGMVPVLVDGITRYGFNYISPVSGSSNMA
                     QAGSAFGVWLKAKDKDLKAVAATATISALTGVTEPAIYGVNLRLKKPFLCAAIGGAAG
                     GGFAAYFQCKAFAMGGPSFLTLPMFIGEGGHVGLVAIAFTIAFIVSAIATYIVGFEEE
                     VTADSHANL"
     gene            55705..56439
                     /locus_tag="KOU88_001578"
     CDS             55705..56439
                     /locus_tag="KOU88_001578"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010990049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBK3211477.1"
                     /translation="MKIYLTKDYEEMSQVAAQMVLKYMYSNDNKRINLSITAGQTPKR
                     TYEILSEFVKNKPYFENVHYYNFDEIPIKGEKVGVTIRNLTNMYFREAQIPEERIHVL
                     DENNYQGFDRKIEADGGIDMVLMGLGWDGHFCGNLSGTVNSFDEETRAVSTYITDDMA
                     KLLTKSVGGNPEKLFDYYVTYGPKTIMHCKNIIMIVNGKHKAQILKQTLFGPLDLLCP
                     SSLLRLHPNFTLIVDEEAASEIKDLI"
     gene            56528..57727
                     /locus_tag="KOU88_001579"
     CDS             56528..57727
                     /locus_tag="KOU88_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006875852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3211478.1"
                     /translation="MYNHMKKVFQGLEGGLFSSVEKADVGDSYQKLGEQGVSLMGWAD
                     PFFPDYCIPRHILDAATLAISSNMSTHYTAPVGNDLLKIEIAKKLKEVNNLDVDFKRN
                     ILITPGSDSGLYYSMLPFINEGDEVLIPTPCYPNNIQNTKLMGGVPIFVELKESDGYQ
                     IDITEFEKRLTNKTKLVVLTHPNNPTTTIFNKESLEKLAKFIIDNDLILICDQAFEDF
                     TFENELITPASLEGMFERTVTIFSTSKGMGLSGFRVAYMVCSDKLMDKYYGAAVTVLG
                     ATNTVAQMSTIEAFKDRSFMEDFERVFDKRRQEAYKIINEIPNVSMQMPESGFLGWIN
                     VSKLGTSSEIQKYLVDEAKVCINDGINYGPGGEGHLRIILGSYKDDSKVIGALNRIKD
                     ALIKKQQ"
     gene            57751..58233
                     /locus_tag="KOU88_001580"
     CDS             57751..58233
                     /locus_tag="KOU88_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015529974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3211479.1"
                     /translation="MLSIFKSKKNDNKLKAFASGKVIPIEDVDDNVFSSKMLGDGIAI
                     YPTNEYVVAPCDAEVNIIMKDTKHAVGIKLFNGMEILFHVGIDTVSMNGEGFEIFVSP
                     GDKIKRGDKLISFNSKLIKEEGLQDVVIMVVTNSEQYKNIKYHIGLEAVIDDTIIAEI
                     "
     gene            complement(58551..59148)
                     /locus_tag="KOU88_001581"
                     /pseudo
     CDS             complement(58551..59148)
                     /locus_tag="KOU88_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(59392..59820)
                     /locus_tag="KOU88_001582"
     CDS             complement(59392..59820)
                     /locus_tag="KOU88_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211480.1"
                     /translation="MKIHSIQNLTLDTRNLIKKYSLTLNEDLIWEFKHGKYHTIKYFT
                     HKFAVKESVLALLCNIHKLCYAKIKYFESSFSKYEPYKYSYQNEFVKCEMYDMNFMFH
                     KYSNIMIDLRNLQEIKTIEEFRLFCDYLESFEDNLQDLII"
     gene            complement(60221..60682)
                     /locus_tag="KOU88_001583"
     CDS             complement(60221..60682)
                     /locus_tag="KOU88_001583"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBK3211481.1"
                     /translation="MIYEGKLIGKDLKIGIINSRFNEFITSKLLSGAEDCLLRHDVSP
                     ENIEIVWVPGAFEIPLVAQKMAKSGKYDAIICLGCVIRGATSHYDYVCSEVSKGIAKV
                     SLDSELPVIFGIVTTENIEQAIERAGTKAGNKGYDCAMNALEMANLFKSLD"
     gene            complement(60787..61980)
                     /locus_tag="KOU88_001584"
     CDS             complement(60787..61980)
                     /locus_tag="KOU88_001584"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HBK3211482.1"
                     /translation="MFNTIEEAIEDIKNGKMVIVVDDESRENEGDLLMAAEMATPESI
                     NFMATYGRGLICLPATEKKFKSLNIPLMVRENTDTFQTAFTVTIDGADTLTGISAYER
                     AETVKLFCDENSTSKDFKTPGHIFPLIAKTGGVLVRDGHTEASVDLARLAGFKEIGLI
                     CEIMKDDGTMARVDDLMIFKEKHNLKIITIKDLIEYRKINETTIEKVSSAFLPTKYGN
                     FEIIGYRDTYSNEEHIALTYGNINIENTLVRLHSECLTGDVFHSLKCDCGLQLESSMK
                     KIVENGSGVLIYMKQEGRGIGLLNKIKAYKLQEEGYDTVEANLMLGFEEDMRDFYMAA
                     QILKNLNIKSINLLSNNPDKINQLEKYGIKIENRIPINEEINDFNKLYLKTKKDKMGH
                     LLDII"
     gene            complement(62003..62668)
                     /locus_tag="KOU88_001585"
     CDS             complement(62003..62668)
                     /locus_tag="KOU88_001585"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBK3211483.1"
                     /translation="MFTGIVEEVGILRKITANGKSGKVTILSNKILDGTNLGDSIAVN
                     GVCLTVSNLGKNEFTADVMMETIRSTNLGLLNANDKVNLERAMSLSSRFGGHIVTGHV
                     DGKGTICKFEKDENAVLVSIRPDKKLLSSMILKGSVAIDGVSLTISYLDDEIFKVSII
                     PHTKINTILLTKNVGDFVNLESDVIGKYVNNFMANNYKELNSNSSNHKSNIDKDFLFK
                     NGF"
     gene            complement(62702..63814)
                     /gene="ribD"
                     /locus_tag="KOU88_001586"
     CDS             complement(62702..63814)
                     /gene="ribD"
                     /locus_tag="KOU88_001586"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBK3211484.1"
                     /translation="MNFVNQKEKDIYYMKKAIELAKNGEGFVNPNPLVGCVIVKDSNI
                     IGKGYHEKFGSNHAEVNAINSAKQSLKDSTLYVNLEPCSHYGKTPPCVDKIIQNKIKR
                     VVISTLDPNPLVCGNGVKKLKDNNIDVTVGILEDEARDLNEAFFYHIKNKRPLCIVKS
                     AVSLDGKIATKSLESKWISNESSRYLTHKYRNKYQSIMVGINTVLNDNPLLTCRLNQE
                     KVSHPTRIVIDTHLKLPLNSNLVKDKTSKTIVFTCCKESIKLSMLKENNVETIISPSK
                     NNLVDLEFVMYKLGELNIDSVLVEGGATLNDSLFRNKLVDKVKLFLSPKIIGGKDAPT
                     FVSGEGINHLSDSTQLTINNVTLIDGDILIESDVLN"
     regulatory      complement(63946..64067)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            64256..66739
                     /gene="recQ"
                     /locus_tag="KOU88_001587"
     CDS             64256..66739
                     /gene="recQ"
                     /locus_tag="KOU88_001587"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBK3211485.1"
                     /translation="MNKKLLEILSKYYGYTSFRKGQESIINSILSEKDVLAIMPTGGG
                     KSICYQIPALILDGMTIVISPLISLMKDQVDALKTMGISAAFINSSLSSKEFNEILNN
                     IRKNNYKILYIAPERLDAQEFIELINNNNVSQVAIDEAHCVSQWGHDFRLSYRRISDF
                     IKNLPKRPIVTAFTATASEEVRTDIINLLCLENPDYYITGFDRENLSINIVKSSSKNK
                     YILDYIQNHKNESGIIYVATRKEVENIYNGLSKRNISVSKYHAGLSKNERSKNQEDFI
                     NDNVDIMVATNAFGMGIDKPNIRWVIHYNMPQSIENYYQEIGRAGRDGEKSECVLLFS
                     PGDVHIQKYLIDIGVENPERKLFQHKKLQYMIDLVYSNSCYRKTILSYFGENYIDNCN
                     NCSNCLVEGEIVDKTIDAQKVISCVARMKRSYGVTTIVDVLRGSKNKKILQLGLNTLS
                     TYNIMRDYSSEDLKNFINTLVSHGFLDLVETLGNGNRGSFPTIRLNEMSMKVLKGEVK
                     VEFKEIVMTKSLEVEDELYNALRELRHSIASEERIAPYMVFGDGTLRAMSSSYPINKE
                     EMLDISGVGEIKYQKYGRDFEAVIKEYVEKNNINKKIDEKNVDSKNVNSDFLEVNTDK
                     VLYEKLLVIREEYATKEKLPAYMILANKALKEISGRYPLDEEQLKDISGIGGVKFEKY
                     GASILAEVNKYVKENNINVIWEKKGKRKLILDGESRKNNEIALDLLNQGKDIQSISQE
                     IEVSLSTIIGYVHDYVKDGHSISFELGLENFYNEDKKKMILEVCEKVGYDNLNNIKRK
                     LPDSIKYENIRAVILDSYLENLKNNIIAE"
     regulatory      66828..66939
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            67081..68382
                     /gene="thiC"
                     /locus_tag="KOU88_001588"
     CDS             67081..68382
                     /gene="thiC"
                     /locus_tag="KOU88_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBK3211486.1"
                     /translation="MNYTTQMDAARKGIITKEMEIVSQKEQVDVNELRELIANGQVVI
                     PANKNHKSLSAEGVGKNLRTKINVNLGISRDCKDIEKELEKVRVAIDMKAEAIMDLSN
                     YGKTREFREKVVEMSPAMIGSVPMYDAVGYLEKELKDITEEEFLNVIRQHAIDGVDFI
                     TIHAGLTRSVCQKIKNHERLTHIVSRGGSLLFAWMELNNKENPIYTNFDKILDICEEY
                     DVTLSLGDACRPGCIKDSTDGVQIQELVVLGELTKRAWERNVQVMIEGPGHMAIDEIE
                     ANVVLEKRLCHGAPFYVLGPLVTDIAPGYDHITSAIGGALACAKGVDFLCYVTPAEHL
                     RLPNLDDMKEGIIAAKIAAHAGDIAKNVKGAREWDNKMSKARADLDWCEMFRLAIDPE
                     KAKRYRDESTPTHEDSCTMCGKMCSMRTVKKILNNEELNLI"
     gene            68436..68630
                     /gene="thiS"
                     /locus_tag="KOU88_001589"
     CDS             68436..68630
                     /gene="thiS"
                     /locus_tag="KOU88_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBK3211487.1"
                     /translation="MKVNGKEIEFEKDLTVIDLLNKYNLKSDRVVVEVNLEIIEESNY
                     NTYVLKDEDIVELISFIGGG"
     gene            68623..69426
                     /gene="thiF"
                     /locus_tag="KOU88_001590"
     CDS             68623..69426
                     /gene="thiF"
                     /locus_tag="KOU88_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiF"
                     /protein_id="HBK3211488.1"
                     /translation="MVKIKIFVNELLTDVEENTTAYKVRDSYNNKCDVLVLNGYPIKT
                     DMPLFENDKLTLIQKGVKPSLDELESLLIARHTPNIHNKLKKGKVAILGLGGLGSNIA
                     ISLARIGVGELLLIDYDVVEPSNLNRQQYFIDDIGKLKTDAMIENIKKINPFIKLNKR
                     DIFLNKNNMDTIKDSDLIIEAFDDASCKAQVCNYVLINLKDKYLIASSGMAGYYDSNI
                     ITTKKIKDRFYICGDFVNEAKFGKGLMAPRVAICANHMANLATQILIDM"
     gene            69489..70259
                     /locus_tag="KOU88_001591"
     CDS             69489..70259
                     /locus_tag="KOU88_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBK3211489.1"
                     /translation="MDKLILGGHEFNSRLLVGTGKYGSNNILPEVIKESGSEIITMAL
                     RRVDLDNKQENILTYIPKEMTILPNTSGATNAEEAVRIARISRKMGCGDFIKIEVISD
                     TRYLLPDNEETIKATKILADEGFIVLPYMTPDLYAGRRLIEANAAAVMPLGAPIGSNR
                     GLQMKEMIRIMIDELDIPIIVDAGIGKPSQAMEAMEMGADAVLVNTAIASAGDPVQMA
                     RAFKLAVEGGREAYIAKTGNVSEFANASSPLTGFLGNL"
     gene            70276..71379
                     /gene="thiH"
                     /locus_tag="KOU88_001592"
     CDS             70276..71379
                     /gene="thiH"
                     /locus_tag="KOU88_001592"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBK3211490.1"
                     /translation="MSFYDVIEKYRDFDFDGYLNNVTDNDVLRSLSKDKLEDFDILNL
                     LSKTAVKHLEDMAQKAHKLSVQYFGKTVCLYTPMYIANYCVNQCVYCSYNIKSGIKRK
                     KLTMDEIREEGEAISKEGFKHLLVLTGESSFHSSVEYIGEAIEILREKFPSIGIEVYP
                     MEVEEYKYIVDKGVEGLTVYQETYDEEIYKRVHIKGPKSNYKFRLDAPERGAKAGMRT
                     LSIGALLGLNDFRKETFFTILHGKYLKTKYPHIELSYSTPRMRPFKGCFEELVDISDT
                     DLVQAMVCMRLFDPHAAINISTRENLEMRSHIIPLGVTKLSAGVSTDVGGHSQDEHDT
                     AQFKINDESTVKDVEKMLNSIGYQHVFKDWERF"
     gene            71380..72069
                     /locus_tag="KOU88_001593"
     CDS             71380..72069
                     /locus_tag="KOU88_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBK3211491.1"
                     /translation="MYLITNRKLCSEERYLEVIKESILSGVENIIIREKDLEYQELRK
                     LYMKIKTKINCIDFQEQISDESLKTNINQKECRNKFKVNFIINSNIEFFEKVDCQGIH
                     LPFKLFLNLIENKYNFNENKILGLSLHKVEEVDYLEKLIRNQNIKIDYITLSHIYETK
                     CKEGLNPKGIELLKEAKKITDIKIIALGGILPSNVKETLKYCDDFAIMSTIMRSKDIK
                     KTISNYNEKLN"
     gene            72257..73651
                     /gene="yfcC"
                     /locus_tag="KOU88_001594"
     CDS             72257..73651
                     /gene="yfcC"
                     /locus_tag="KOU88_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBK3211492.1"
                     /translation="MTDSKKKRFIIPHTFTIIFLLIVLMAILTWIVPSGEFSREDVEG
                     RMVVVPGTYQSVESNPQGFADVFKAPIEGFIDSAEVVGFVLIVGGAFGIVNRTGAIEA
                     GIASVISKFKGKELLIIPISMILFGLGGTTFGMAEETLPFYMIFVPLMTSLGYDSLTA
                     IAIVFIGAAAGAAASTINPFSVGIAQALAQLAPGSGVTYRVVIFIAYILISIAFVMYY
                     AKKVKENPESSIVYEIDKNNKSILNQTSTEIKEFTFKEVSVLAIFGIGMAIMIWGVLS
                     QGWYIPEISMCFAAIGVLSGLVGRLSQIEISESFIDGAKDLASAALAIALARGIVIIA
                     QNGFIIDTILNSAAAFLGGLPKVIFVYLSFFLEAALAFLIPSSSGLASLTVPVLAPLG
                     DLVNISAQVIVTAYQFGVGLTNFITPTSGVLMGALAVAHIPFSKWVRFIMPILLILTA
                     VSLVFLTIGIYIGF"
     gene            74168..75535
                     /locus_tag="KOU88_001595"
     CDS             74168..75535
                     /locus_tag="KOU88_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBK3211493.1"
                     /translation="MGLKEFDFIEESIDMLRTMSPTLETISDEIEEYFENILDEKNQE
                     YINVTSRIKSESSLREKIIRNRYLKKYGEASNLIHNVSDLIGLRIECRFIEDENKIYR
                     LLRRYFNKTDDKINYYNKENKNIKLKLSERQPNKQKNGFEIYKIDGVFAYLDREVKFE
                     LQIKSLVNVFWSEIEHKIIYKNNTYLLADKFIKDMMDSIKNNLTMIDNQLLSIYKNFH
                     SGKSFNMKVSKKEIEKLFAKLVYDAFSEKMNKSIGFVVDFKKPCETILNYSFNKQDIS
                     DEVLGNFMLDEFARLNEIVNKDIDFNEQIEFEREPTFDDKFCKDLGNHFRSRLNTEFP
                     WNLFFRILFEIEPYNNTKDFENFVEFIKENVLLEENREQLLCQFEEDSKLIIEDIYDC
                     IFNSISEIDSVEILYNYNLEKINFTSSEIINCICREYECYGEYLEEKEKLMNTFKEKI
                     IQIFE"
     gene            75560..76168
                     /locus_tag="KOU88_001596"
     CDS             75560..76168
                     /locus_tag="KOU88_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase"
                     /protein_id="HBK3211494.1"
                     /translation="MRHFSNIYELSKIILEEAICIEKTGVILAGGRNSRMGRDKAFLE
                     LHDKLFIEIAIEAFKNFDELIIISNNEELYSKYDIKVYNDIVKDVGPIGGIYTALEYA
                     KYDIVTIACDMPYLNNQIVERIANKMDDKSVISVTNGKLQPLCSGYKKSIINKVSLCI
                     RENDLKLRSFIDKIDKSYIYFDEEDLFLNVNTVDEYKKLTKV"
     gene            76216..76587
                     /locus_tag="KOU88_001597"
     CDS             76216..76587
                     /locus_tag="KOU88_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBK3211495.1"
                     /translation="MNLLKCDSWAVILNNSDKESKAYKILDELKRNMYKVVAIDEEKK
                     PIEGIDVYECLKDVPHNIDVVAIIDKQSKMDVILEEVELLDIQNMWFEKGSFSEMMIK
                     KTKDLKLNIEYNLSLYDELTR"
     gene            76766..77104
                     /locus_tag="KOU88_001598"
     CDS             76766..77104
                     /locus_tag="KOU88_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBK3211496.1"
                     /translation="MLIVTTEKVEGKKISKVLGLVRGSTIRAKHVGKDIGASFKNLVG
                     GELTGYNEMLTEARQIAIGRMVEDAEAKGANAVIAFRLSSASVMQGAAEMLAYGTAVV
                     LEDDNSILEK"
     gene            77570..78073
                     /locus_tag="KOU88_001599"
     CDS             77570..78073
                     /locus_tag="KOU88_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MogA/MoaB family molybdenum cofactor
                     biosynthesis protein"
                     /protein_id="HBK3211497.1"
                     /translation="MFNVAIITLSDKGYEGKREDITGKKLTEFVENTGAYKVTEYVLI
                     KDDKEMLKENIIRLCNSNKIDLILTNGGTGFSKRDITPEATKEVLEKEIPGLSEYMRM
                     KSTEITKKAILSRGVSGIRNNSIIINLPGSPKGAVENLSFIIDVLDHGIEVLRGEATE
                     CATKKSE"
     gene            78120..79079
                     /gene="moaA"
                     /locus_tag="KOU88_001600"
     CDS             78120..79079
                     /gene="moaA"
                     /locus_tag="KOU88_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBK3211498.1"
                     /translation="MIDKYGRKIDYLRISLTDKCNLRCVYCMPPDVKFDKNYINENLS
                     FEDYKFIIKAMAEQGITKIRFTGGEPLLYPKLNELIKFTKEECGINNIGMTTNAIGLS
                     DRIFELEKCGLNKVNISLDSLKEYKYKSVTRGGNLKDVLKSIESCLNLGIKVKLNCVA
                     ISGFNDDELKDFMFLTVKSPIDVRFIELMPLGEANRVYKKGYFNVKEMIEKIYGLYKV
                     KNDEKSTAEYYMFKGAKGRIGIITPLSCSFCNTCNRIRLTSSGAIKLCLHSKEEIDIK
                     PFLHKPLLFRESMKDIIKQKPEKHHLLENKCSDTNRRMYEIGG"
     gene            79083..79553
                     /gene="moaC"
                     /locus_tag="KOU88_001601"
     CDS             79083..79553
                     /gene="moaC"
                     /locus_tag="KOU88_001601"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBK3211499.1"
                     /translation="MLTHINEKGYAKMVDISEKDDTKRTAVATATITLSKEALEKVKN
                     GQIKKGDVLSVAQVAGIMGAKNTSSNIPMCHQIKLVGCDLEFDVDDSMSAIKIYATCK
                     SLGKTGVEMEALNACSLAALTIYDMCKAVDKKMVISNIHLVEKTGGKSGDFKFE"
     gene            79589..80020
                     /locus_tag="KOU88_001602"
     CDS             79589..80020
                     /locus_tag="KOU88_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HBK3211500.1"
                     /translation="MAKVVSINISEKKGVIKVPVQCAELKINHGIVGDAHAGNWHRQI
                     SLLGKESIDKMKMEGFDQLKYGDFAENVTTEGIEVFSLPVGTKLRIGQCEVEVTQIGK
                     KCHNGCEIKKLTGDCVMPREGIFVKVLKEGIINVNDSIDVI"
     misc_binding    80451..80662
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            80825..82114
                     /locus_tag="KOU88_001603"
     CDS             80825..82114
                     /locus_tag="KOU88_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBK3211501.1"
                     /translation="MEEEKINYALEQIPENQKRGWVAMFSVLVAIGVDLSSVILGAEL
                     AQSMPMKQAILSVIVGSFFSAILYTTCSLVGSSTSLSTSMITKYVFGEAGAKIFSLVI
                     GVSLLGWFGVQVGFFAQNAQIIIKDIFNLDVSMQILSLIGGLLMMSTAIYGYKAMEKL
                     SVYSVPFLLVLMMLTIFLAFRANGISVDDNMKSTMTFAGGVSLSMSIIIVGAIVSPDI
                     SRWAKSRRDCALSSFLGIQFGNAFMIIVSIVLVKCMGTSDIMRIFITLGIAIPGIIVL
                     TLAQWTTNTSNVYSASLSIALVLKKAPEKVLTIVLGIIATLLAVFGIYEGFIGFLNLL
                     GIVIAPVGGVYTAEYYIVKQELKGFDKGVLYKPIVKRSIVSWIIGILITYLSTYGFIT
                     LTTIAPLDGFIAGFVVQSIIGKVLCSTKNKQEIDKAV"
     gene            82168..83247
                     /locus_tag="KOU88_001604"
     CDS             82168..83247
                     /locus_tag="KOU88_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF917 domain-containing protein"
                     /protein_id="HBK3211502.1"
                     /translation="MRFLTEESVDKIAVGAAVLGTGGGGDPYVGKLVAKQAIKKYGPV
                     KVISLDELDDDALVVPVSGMGSPVITIEKLLSEVELTTPLEIMEKLLNRKVDVIIPIE
                     IGGINSLMPIAVAAKKGLPILDADSMGRAFPEAQMVTFYLEGYEASPAVMSDEKGNSA
                     ILYPVDGIWSERLARTLTVEMGGSSSISDYNLSGAQVKKAAIGNTLTIAETIGGFLLE
                     NKSDSKGAVENILKELHGYKLFEGKVIDIKRELKGGFTRGHAFFAGINEYDGEYSILF
                     QNENLIAKKGDTPLCITPDLIAVLDLETGFPITTERIKYGSRVMVVAFPCNEKWRTEK
                     GIETVGPGYFGYDVEYKTVEELQGK"
     gene            83268..83633
                     /locus_tag="KOU88_001605"
                     /pseudo
     CDS             83268..83633
                     /locus_tag="KOU88_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423610.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
BASE COUNT        32018 a         9254 c        13496 g        28955 t
ORIGIN      
        1 gaacttatat attagaaaaa aatttttgta tatatagagg actctaaaga tgaactatgt
       61 aaaacaaggt ttatatattc taatagtata gaaaaattta ttgtaaacgc atgtatatta
      121 ttagaaaaaa tagtttgaag gtattcaata aacataaaaa acaatatagg ggataaaggt
      181 gttttatgaa gagatttttg aggagaatta tcttagtttt atttattttg ttgattttta
      241 taagttttat ttctattaaa ttaattcata atgttggaga ttatggaaaa ttgattaatt
      301 atgttgggat tgttcgtgga gctagccaac gtctaactaa actagagatg aatcatcaac
      361 caaatgatga attaatagaa tatattgatg aaatcctaca ggagttgatt acagggcatg
      421 gagattatgg tttagtaatc actgattgta atgaatacaa tgaggactta cttttattag
      481 aaaaaaagtg ggaagattta aatattgaaa ttaaaaaagt aagaatgaaa gaacagaata
      541 accagttatt aagtataagt gaagagtttt tttctcttgc aaatgataca gtgtttaaaa
      601 tagaaaactt ttctaaagaa aaaagtaatt acttaatgac tttaataata attatatcta
      661 ttataggtat attagcatgt atcatattga ttttacaata tagtaaaaaa atggttagac
      721 tggaaaaatt aaatgtagat ttaaaaaata ttgcatataa agatgaacta acaggagtaa
      781 atactataga aaaatttaaa ttggatgcaa atcaaaatat ttgtatacat aaggataaga
      841 aatttgctgt attctatatt gattttgaaa actttaaata cattaatgat atatttggat
      901 atgattatgg tgacatgata ctgaaaagat atgctaatct tatgatgaat gacataggga
      961 aatatgaaat atttgcaaga gaaattgcag atagatttgt tgcgttaaga tgctatgtag
     1021 ataaggaaga tttagtggta agacaacgag atgtagacaa tgaactaatt aatataacaa
     1081 atgaaattaa aaataaacat agtattactg ttgttagtgg aatttgttgt attgaagatg
     1141 taaatgaaaa attaagtata gatggtttaa taaatagagc aaattttgca caaaaaactg
     1201 ttaagaataa accaggtact aattatgctt tttataatga cagtattcgt aaaaaaatga
     1261 ttgaagaaaa tactatcaag agtagaatac atgaagctat tgaaaaaaga gaatttatag
     1321 tttatttaca gcctaaagtt aatttacata gtcaaaaaat aaattgtgca gaagctttag
     1381 ttcgttggct tactccggat aaaggtatta tatctccagc aatatttatt ccagtacttg
     1441 agaagaattt ttttattgcc ttagtagata agtatgtttt tgaggaggtt tgtaaatgga
     1501 ttagaaagag gttagatgaa aataaacctt ttgttcagat atcagttaat gtttcaagaa
     1561 tacaatttta taacactaaa tttgtagaaa cttattccaa tatacaaaat aaatacagga
     1621 tacctaaaaa tactatagaa attgaattta cagagagtgt tgcttttgag aatcaaaaac
     1681 atcttttgga aattatacat gatttgcatg aaaatggatt tacttgttct ttagatgatt
     1741 ttggaaaagg ttattcgtct ttaagtgttt taaaagattt accatttgat gttttaaagc
     1801 ttgattctat gtttttcaag gctagtttag ataaagataa agagaaaata gtaataaaaa
     1861 atattgtaca tatgttaaaa gaacttaata tcacaactgt tgctgagggc attgaatgca
     1921 aggaacaagt tgaatttctt agggatattg ggtgtgattt agttcaggga tttgtatttt
     1981 ataaaccaat gccaatatta gaatttgaaa aaatattgga taaagagttt gtttataata
     2041 gctaaaatgt actttataaa atatgaacta attaagtaaa attattttgt actgaataaa
     2101 tttttacttt atttacagaa aagcgcgaaa agtgtattcc tttaagtgtg ggatggatag
     2161 cacaaataga ggagaaaaaa tattggccat ataagaatgc ataataatat aaatatttga
     2221 aaggtcagca ttatataaaa attaaaaaga aaataaataa tttttctata aaaaagagac
     2281 tatgagaaaa tttactcata gtctcctaaa taatgtattt attttcttcc tgcaacccat
     2341 tttaatcccc aatgaaattc agtatccatt tctctatgac ctttgaagta tttaactact
     2401 ttttcaacac tgaatgtctc atcatttaca ttttctatca atgctattga acacatatta
     2461 tagccatttt tatgttcatc aagtttgaca actaagtctg aatcttgttt ttgtttgatt
     2521 gttacaattc catcagcttc agaccagtta gctacacctt cgtatataaa agcataaata
     2581 agtattcttt ttatatcttt tattttatta ccatttattc ttaaattttc tccttgtgta
     2641 ttacttcctg ttctgtcatc tccatctaat tgagcaaaag gtggattgtc taaactacca
     2701 aaggcatttc ctaatgcttg aacagctcct tttacaccat ttttcatctc aaataggcaa
     2761 cccaaatcta aatctatatt actgcttctt aaagagccaa aaaaaccctt tttttgtact
     2821 ttttgattcc aatttaaatt aactaagatt tcacctaaat cgctattttc cttttttgta
     2881 aggtttattt tttgtccctt ttttaattct atagccatag taatcttcct ccacaaacat
     2941 agatttattt aaatggtagc acttaataag tcaatattca acaagattag aataataata
     3001 ttaaaattat actaaatata ctaaaaagta ggaatcacaa tacctttgta tttttcttca
     3061 attaagcttc ttgctttatc tgatgtaaga acatcttgta gaactttaat cttttcactg
     3121 tctttatctt cagttctaaa tgctaaaaga tttgcatact cgtcatttat aggagctgta
     3181 taaattccgt ttttcttggc atcaagacca gcaggtacag cataagtagt atctataaat
     3241 gcagcagtca catctggaag agaagatgga atttgagcaa tatctaactc tttgaattgt
     3301 attccctttg gattttctat tatgtcctta ggactaacta atccatcccc tttaggtaac
     3361 gttaaaagtc caatactttc aaggtatcta aggttcttag aacaagaaga tgggttattg
     3421 cttattgcaa ttgtatctcc ttttttaaat tcatcaacag attttatctt ataagagtaa
     3481 agtattgctg ggcatacata tagtttttta ccagccatta ttttgtaacc tttggcctta
     3541 acagcttctt ttagataagg ttcatgttga aatagatttg catcaatttc accattattt
     3601 aaagcttcgt ttggaagtat gtaatcatca aagtttttaa cttctaaagt atatcctttt
     3661 tctttaataa gtggttttaa ttcttctaat aactctcctc ctggaactaa agtagcacca
     3721 acaacaattt ttttatcatc tttagcttta gaacatccaa ccacagctaa agttaatact
     3781 agacataata acaaacataa taattttttg aatttcatat aaattccctc ctgaatataa
     3841 ttgattagtt aaaaataaaa taccattctt tatcacactg caaaataaaa ataagcctga
     3901 gtttaaactc aggctttaaa agctaattta gactcatctt tcagtataat actgcaggat
     3961 ttagcaccaa tgtatataaa aatatactgg ttgctgggtt tcatagggcc agtcccttca
     4021 ccactctgga taagaagtat caatttttaa ttatgttata aatattatca tgatttttta
     4081 cgtctgtaaa cataatttta taaatatttt aaaatcttta atgtatttta tttaacacct
     4141 aaaattccag aaactagaat atcagtatca gcacctaaga aatagtcatt tatttcaata
     4201 gaatccagag tatttctcaa agcattttct tcatgcctta taccaataag tttattttct
     4261 acaaatgcaa catcacattt tccaaaaaaa tctccaaaaa attttatact agttattatg
     4321 cctttatcaa catttaaatt aaactcaaca tttccaccag aatattttaa ttcatttgaa
     4381 agagtatatt ttggtgaatt accaaaattc caatcccaag tttcgtattt tgatttagta
     4441 agcttttcta tttgttttat atcatgctca ctcaaacaat aattagtatt atcagtattt
     4501 gttttagaaa gataatccat tatagcatct ttaaattcta atatgtccat ttttgaatgt
     4561 aaatgttcac ttatattggt tacacgagat tttacagatt ttattccttt tccttcaaat
     4621 tttataggtt taacctttaa tgcttttgag aggtcattta tttcagatga aaataaaaga
     4681 gtaccatgat gcattacttt gtttttgtag ttgtattgag catttccaga aaatttcttg
     4741 ccatctataa gaaggtcatt tcttccagaa aattcggcat tgacatctag tgttttaagt
     4801 aaatctatta tgggctgagt gaatcttctg aaatcactaa aattattatt gttacaagct
     4861 ataaatgtaa aatttatatt tcccaaatca tgaaatacag ctccaccacc agactgtctc
     4921 ctaacgacag gtatagaata ttcttttata tattctaaat ttatttcaga aagtgtgttt
     4981 tggttttttc caacaattat agaaggttca ttcctccata aaataaataa gtcttcatca
     5041 aaatttttta gaagatattc ttccattgct aaattaaaat aagggtttgt tttttcatta
     5101 taaattaata acattaaagt agttcctcca tagaattgat aaaattttta ttatgaatac
     5161 aattaatttt ataattcgac aataatataa aaactccttt aaattagaaa ttttaaaaac
     5221 taccttgcaa agtttaaata aataatatat actcaaaata tgtttaataa aagtgaatag
     5281 aagggtagag gcgcaataat ctatcagtac taataaggag ttaagcacag agatttatta
     5341 ggaaaggaga tattgccgaa gttttataat cgatgcttta agattatatt gctgggggta
     5401 catagaaaat atgtacaact gtcacaggtt tatttgtggt gagctatcat ttaaggaatt
     5461 atattatatt tatttttact attgttgata tattgtaatg tttaagcctt gagtgtttac
     5521 cactcaaggc ttttttagtt ttattgtaac ataataccct gtacagttca caaaattaaa
     5581 aggagaggga gatttatatg aggaacaaaa aaattaatat tatttttctg acgacaatca
     5641 tgttcataat gtcaacagta atggtttttg cagaagaaga tatagacact attgcactag
     5701 ccaatgcaga aaaatttggg attttaactt taataccacc attagttgct ataatacttg
     5761 catttataac taaaaacgta ataatttctt tacttatagg tattctttct ggtagtttta
     5821 taattaaagc tagtggtatt aatgtttttg cgacatttat acaggcattt ttagatttag
     5881 tagacagagc tttagtatct ttagcagacc cttggaatgc agggataata ctacaggttt
     5941 tggcaattgg aggagtaata aatcttgttg ctaaaatggg aggagctaaa gctatagctg
     6001 aagcacttgc taaaagagca aagtcagcaa aagggacaca gcttataaca tggtttttgg
     6061 ggcttttagt attctttgat gattatgcca attcactaat agtaggtcct atgatgagac
     6121 ctgttgcaga taaaatgaaa atatcgagag aaaagctagc atttataata gatgccacag
     6181 cagcaccagt tgctggttta gctataatat ctacatggat aggtcttgag gttggtttaa
     6241 tacatgatgc ttttgaaagt ataagtatag atgtagatgc atttggtata tttttaaata
     6301 caataccatt tagattttac aatatattaa tattagcttt cattgtaata tcagcattat
     6361 tattaaaaga atttggtcca atgagaaaag ctgagataaa atctagaagt agaaaaatta
     6421 gtatagacct tgatgaaggc gtagaagagt tggatgattt agctccaaaa aatggagtaa
     6481 aattgagtgt atggaatgct ataatcccaa taggaacatt gataatagtt gcattagcat
     6541 cattttatta tagtggatat acatctataa tgggaggaga cgataaggct ctgatacaac
     6601 tatttacaaa ttctccatat tcttttgaag caataaaaga agcatttagt gcatctgatg
     6661 catctagagc attattccag tctgcacttg ttgcaagttt agttgctatt ataatggctg
     6721 tagtaaaaaa gatttttaca atatcagaag caattgatgt ttggatagat ggaatgaaaa
     6781 gtttagtaat cactggtgta atattaatac ttgcatggtc attaagttca gtaataaaag
     6841 agttaggtac agctaaattt ttaatacacc tattatcagg ttcactacca ccattcttat
     6901 taccaagttt aatatttggt ttaggagcaa taatatcttt tgctactgga acagcttatg
     6961 gaacaatggg tatacttatg ccacttgcaa ttccattagc atactcatta aatcctgata
     7021 tgtcttatgt aatagtaagt actagtgcag ttttaacagg tgcaatattt ggagaccatt
     7081 gttctccaat ttcagataca acaatacttt cttcaatggg agctggctgt aatcatatag
     7141 accatgttaa cactcaaatg ccatatgcta tatttacagc agtaatcact attgtatttg
     7201 ggtatatacc agctggactt ggattgccaa tatatatagt attaccagtg gcaatagctg
     7261 ctatatttgt aggtattcaa ataattggta agaaagttga tgaagcggaa atagaacttg
     7321 tagaataaag atataaataa gtttcacctt ttattatcac tattttgtta gtttttagat
     7381 aattttaaaa agttattgaa aataatggcg aaatatagta aaataaaaga gtgataagcg
     7441 gatgtggcgg aattggcaga cgcactagac ttaggatcta gcgccattgg cgtgggggtt
     7501 cgactccctt catccgcact ttacagtact taattgtact gaaaaaaact ggggttgctg
     7561 gctttcggag tgggctatcc cgtttttatt tttttgtata tataatagat tggcacttta
     7621 gtataaggtg ctttttttat aggcaaaaac agtacattta tttctgtttt attatcattc
     7681 atctattaga atatacttta gttaagaatg tgttaataag cagtgttcac attcttgata
     7741 aaatgtggaa taatatgtat ttttactaag acggaaatga aataattaaa ccattaaata
     7801 atattataag atgatgaata agtagataaa tcaaattttg taggaggata ttatggaaaa
     7861 atatatatgg ttgtttccat tactttttat ttttcatgat atggaagaga taataggttt
     7921 tggaatatgg cttaaaaaaa ataaatcaat gcttgataag aagtatccat ttatcagtaa
     7981 agtttatgaa aattatagta ctgaaggcat ggcatttgct gtgtttgaag aatttatttt
     8041 atgcattatt ttctgtatac ttacagttat aacagagaat cagtatgtat atctactatg
     8101 gttaggtagt tttatagcat ataccttaca tttggtaatt catatagggc agtcaatcat
     8161 aataagaaaa tatatacctt cacttattac cagtatcata tgcttaccaa taagcatttg
     8221 gtgtataagt aagagtattt atatagttga ttgtgaaatg agtacaacaa ttctgtacag
     8281 tataattggc attataattg tagcattgaa tttaaagttt gcacagtcgc tgattggaaa
     8341 atttacaaag tggatgtcaa acatataaat tttagtttat tggacagttc aaggaatcag
     8401 aaattggaat tttatagtat taatatttta tggtattaat ataatgtata aaattttata
     8461 gcaatgtatt tcataagtat aaagtgacta gaattttaag aaatatacaa attctataaa
     8521 aactaaataa tttcaagtat attttaaaaa tcttattttt cacaagttta aaattgtaaa
     8581 cgatttcatc aagtctatga atatactttt aacatgttat agtaaatctc aatataaatt
     8641 tacatttggt tctttgtgtg ttattttaat aataaattaa gtgaaaatgt tattttacat
     8701 taatatataa tatctttgca taagagtgaa taatataaaa gagaaataat taataataaa
     8761 aacttaacaa aaaaattaat acataaaaaa aaataaatat aatgtgttga catttaattg
     8821 aaatattcat acaataaaat tgaaaataaa tatttccaaa tgagattagc gagagagtcc
     8881 tttatacgaa aaggcgccga agaagaaatt taagaaatgc caatttttag agaagctttc
     8941 aggcaaaaat atcgctaatt gatgggactc tggagagact taagttaaga tactataagt
     9001 caccgaagaa gcaaaataat attaaattat taaatctttc aggtatacaa acagggatat
     9061 ataggctagg attattttcc atgctgatat atcttttttt tatgaaaaag tacaggaaat
     9121 aatatcaaag ttacttaaat acagtaggtc taattttcta gggagggtta tatatgaatg
     9181 aattgaaaag agtatctttg tacaatatac acaaagagct tggagcaaaa cttgttgaat
     9241 ttgctggttg ggaaatgcct ttagaatatg agggtataaa taaagagcat gagaaggtca
     9301 gaaaaagtgc aggtatattt gatgtatctc atatgggaga ggtacagata aagggagcag
     9361 agtcagaaaa atttatacaa aacctagtta caaatgatat aagcgcatta aagataaatg
     9421 atattatata tacacctatg tgttatgaaa atggtggagt agttgatgat ttattaatat
     9481 ataaatttgg tgaagaagat tatttattag taataaatgc aggtaatata gataaagatg
     9541 tagcatggat aataaaacaa agtgaaggat acaatgtaga tataaaaaat atatctagtg
     9601 aagtgagtca attagcaatt caaggaccta aagcagaaga aattcttcaa aaaatcacag
     9661 atatagactt aaactcaata aaattttata agtcaattcc atcaacaaaa gtatgtggtt
     9721 gtccttgttt agtttcaaga acaggatata ctggggaaga tgggtttgag atatactgta
     9781 aaaataaata tgtagaaata atttggaatg aagttctaaa ggttggagga gaagatatat
     9841 gtccagctgg tctaggttgt agggatactt tgagatttga agcagctcta cctctatatg
     9901 gacatgaaat aaatgaacac atatctccaa ttgaaggtgg tttatctatc tttgtgaaaa
     9961 caaataaaga atcatttatt ggcaaatcaa ttttatcaaa agaaaaagaa agtggagcta
    10021 aaagaaagtt agtaggattt gaaatgcaag gtaaaggaat gcctagaaat ggatatgata
    10081 taaggattgg tgataaaaca gttggatttg taacaacagg atgtgcatct ccaacgacag
    10141 gaaaaatttt aggtatggga attatagatt ctgaatatgc aaaagtagga aatgaaatag
    10201 gtatagcaat cagaaaaaaa gttgttcctg ctgtgatagt taagaaacct ttttataaaa
    10261 aacaatataa aaaagataat attatattaa acaaagaaaa taaattttca tatatacctg
    10321 ctacaagtga agataaatca aaaatgttaa aagtagttgg attaaattcg gttgatgaat
    10381 tattttcaga tataccagaa gaagtaaaat taaaaagaga tttaaatttg gaaattggaa
    10441 aatctgaatt agaggtaagc aaaatagtaa aaagattgtc agaagaaaat ttaagtttag
    10501 aagacttgac ttgttttctt ggtgctggtg catatgacca ttatatacca tcaattataa
    10561 aacatataac ttcaagatct gaattttata cagcatatac tccatatcaa gctgaaataa
    10621 gtcagggaac tttacaagta gtttttgaat ttcaatctat gattgcagaa attacaggta
    10681 tggaaattgc aaatgcatca atgtatgatg gagcaactgc tgcaatagaa gcatgtataa
    10741 tggcaatgaa tcagactaga aaaagtaaaa tagtagtgtc aaaaactatt catcctgaaa
    10801 ctttgtcaat attaagaact tacttacaat ataaagattg tgagatagta gaaattgact
    10861 tttgtaatga atatggcact acagatatag aaaaattaaa agcttctgta gacaaagata
    10921 cagcatgtgt tcttatacaa actcctaatt tctttggaat tattgaagaa atggaagaaa
    10981 tagaaaagat aactcatgaa aataaggcta tgttaattat gagtgtagac ccaatatcat
    11041 taggagtttt aaaaacacca ggtgagatag gtgcagatat tgttgttgga gaagctcaat
    11101 cacttggaaa ccctcttaat tttggaggtc cttatgtagg atttttagct agcaaatcta
    11161 aatatactag aaaaatgcca ggaagaatag ttgggcaaag tttagatgta gaaggtaaaa
    11221 ttgcatatgt attaacttta caaactagag aacagcatgt aagaagagaa aaagcaactt
    11281 ctaatatatg ttcaaatcaa gctttaaatg ctcttgtagc ttcaatatat atagctacta
    11341 tgggtaaaga aggatttaaa gaggttggta tgcagtctat gaaaaaagca cattatactt
    11401 acaataagct tgtacaaact ggaaaatata agccaatatt taaaggtaag tttttcaaag
    11461 aatttgctgt acaaggaaat cttaatatag aaactataaa tgataaactc ttagaagaaa
    11521 atatattagg tggttataat ttagaataca attatccaga attaaaaaat tcaactttgc
    11581 tttgtgtgac tgagaaaaga agcaaagagg aaatagataa gttagttgga ataatggagg
    11641 gattataatg aaagaataca atagtttgtt gatagatata tctaaaaaag gtaggaaagc
    11701 atactcactt ccaaagttag atatagatga tataaaaata gaaaatatga ttgaccaaga
    11761 tatggcaaga caaagtgagt tgaatttgcc agaagttggt gaattagaat tagttagaca
    11821 ttatacatta ttatcaaata aaaactttgg agttgataca ggtttttatc ctttgggttc
    11881 ttgtactatg aaatataatc ctaaaataaa tgaagatatg gcagcacttc caaactttac
    11941 tggaatgcat ccataccaat cttcggatac agctcaaggt tctctttctt tgatgtatga
    12001 tttatcaaga agacttgcag aaattacagg tatggatgaa gttacactac aaccttcagc
    12061 aggttctcat ggtgagttta cagggcttat gattataaaa gcatatcatg aaaatagagg
    12121 tgaccataag agaaccaaag tgataattcc agattctgca catggaacaa atccagcaag
    12181 tgcagctatg gcaaactttg atgtgattca aatagcatct gataaaaatg gagctgtaga
    12241 cataaatgca ttaaaagagg ttttgaatga tgaagtagca gctcttatgc ttactaatcc
    12301 aagtactctt ggtttatttg aaaaaaatat aaaagaaata gctactcttg tacatgaagc
    12361 aggaggactt ttgtactatg atggtgcaaa catgaacgct attatgggga taacaagacc
    12421 tggagatatg gggtttgatg tggttcatct taatcttcat aagacttttt caactcctca
    12481 tggaggtgga ggtccaggag ctggtcctgt tggagttaaa aaagaattag tacctttttt
    12541 accaatacca gtaattgaaa gaaaagaaga taagtatgta ctaaattatg atagagaaaa
    12601 atctattggg aaaattaaaa atttctatgg taattttgga gttcttgtaa gagcttacac
    12661 atatatacta actatgggaa gggatggact taaagaggct agtgaaatgg cagttttaaa
    12721 tgctaattat ataaaggaaa gtataaaaga tgattatatt ttgccaatag ataccttgtg
    12781 taagcatgag tttgtattag gtggattgcc aagaggagag gccaatataa aaactatcga
    12841 tattgcaaaa agactactag attatggata ccatcctcca acaatgtact ttcctcttat
    12901 tataaatgag gcacttatga tagaacctac agaaagtgag agtatagaga cattagatag
    12961 ttttatagaa gctatgaaaa gtgttgctaa agaggcaaag gaagaaccag aactattgaa
    13021 aactgctcca cataatactt tggtcaaaag agtagatgat gcaagggcag taaagaaacc
    13081 tatactaaca tggtcacaaa gataaatagt taaaaagtag agatttaaag tataaagaga
    13141 attaaatttg taagaaaaag ctatctaact taatctagtt tagatagctt ttttgtatat
    13201 tagtatgtat ggtattttct atataaagtt ttaaattata ttagtgctta tatagaatat
    13261 tgatatgatg attatgtata gatattaata agaattgttg aatttatctt gccttaactt
    13321 tatttactct tttatattaa gaaaaactta actaaaatat agcgaaattc ataaaaattt
    13381 aggaaatctt aagaattata atatttaaat ctttagattt atattttatt atataaacta
    13441 tagaataata aaataaaaaa attgagaatt ttataatata tttgtagatt tgagtataaa
    13501 aaagtgctaa gttgaaagga gtaaaatatg gataaggtta atttagaaag gtatagttgt
    13561 gatataaatg ttggtttaaa taaaaatcaa cttcaaagta gaatagatga taatttaatt
    13621 aatgcatttg ataatggaaa aaccaaaaca tataaacaaa tttttaaaga caatatattt
    13681 acacttttta atctcataaa tattgtttta gtctgtttat tagtttcagt tggttctttt
    13741 aaaaatacct tatttatatt tattgctgta attaatacta ttataggagt aatacaagag
    13801 ataagagcta aaagattatt ggacaatcta tctgttatag tttcaaataa ggtatctgtc
    13861 ataagagaaa aagagaaaaa agagattgat gtacaagaat tagtattaga tgatattatg
    13921 attttaaaaa caggtaatca aatttgtgca gattcaaaag ttttaaatgg aaaattagag
    13981 gtaaatgagt ctttggttac aggtgaatct gatattatta taaaaaataa aggcgatttt
    14041 ttatattctg gaagttttgt agtttctgga gaagcttttg taagagttga aaatatagga
    14101 aaagataact atgcaaataa gatagctaat gatgcaaaga tttctaaaaa acataattct
    14161 caacttagaa attcattaaa tgcaatatta aaaattgtag gtataataat aattccttta
    14221 ggaattatat tgtttgcaaa acaacatttt ggaaatggag attctatagc tacatctgta
    14281 gtaggtacag tggcagctgt aaatggtatg ataccagagg gattaacatt acttacgagc
    14341 attgctctag ctgtaggaac tataaaactt gctagtcata aaactttagt gcaagaactg
    14401 tactgtgtag agactcttgc tagagttgat acactatgtc ttgataagac aggtacaatt
    14461 acagaaggta aaatgcaagt tgatgatata gtaatgttgg aagaagtgga tattaatgaa
    14521 ataatgggga atatatgtaa ttctctcaaa gatgataatg caacactaaa tgcaataaga
    14581 gataagtata atgttttaga tacgtataaa gctaagaatt taataccatt ttcttcagaa
    14641 agaaaataca gtggggttac ctttgaaaat aaaggtacat atttattagg tgcatttgaa
    14701 tttatattta aggaaaaaaa taaaaaactt aggatagaag ttgaaagata ttctaaaaaa
    14761 ggaaacagag taatagtttt agctcatagt gattcttata tggaagataa taatattcct
    14821 gaagatataa agccactagc ttttatattg atattggata aaattagaga tgaagctaag
    14881 gaaactttag aattttttta caatgaaggt gtagatataa aaattatatc tggtgacaat
    14941 cctataacag taagtgaggt agctagaaaa gcaggtctta aaacagctag taattttatt
    15001 gatgcaacaa cacttaaaaa tgatagtgat atatacaaag cagttgataa atacagtgtt
    15061 tttggaaggg taagcccaca acagaaaaaa caaatgattt tagcattaaa aaaacaaaat
    15121 catacagtag ctatgactgg agatggtgta aatgatgtgc tagcacttaa agaagcggat
    15181 tgtagcattg ccatggcatc tggaagtgat gttactaaga atgtgtctaa tttagtctta
    15241 ttagattcaa actttgcatc aatgccaaag gttgttatgg agggaagaaa agtaattaat
    15301 aacattcaaa gagcatcttc tttgttttta gtaaagacaa ttttttcatt cttcttgtcg
    15361 ttattaacat tattcttctt cagtagacag tatccatttg ttcctataca attatcactc
    15421 attggggctg taacagtggg tataccatca ttcttcttag ctcttgaagc aaacaaaagt
    15481 agaatttcag gaaatttttt actcaatata ttaaaaaatg ctttaccagg agcactatgt
    15541 gtgacagtaa atgtaattat tgtttacaat atagttgaat atttaggtta tagttcaagt
    15601 gtattttcca caatgtgtgc tatattaact ggtgtatgtg gtcttttaat attaagacaa
    15661 caatgtttgc catttaataa agaaagatta tttttaatag taagtatgac tattgcattt
    15721 gttattggga ttctattttt aggtggatta ttctcatttg tagcattgag tagagaatta
    15781 attctcataa ctatggcatt agcaatatta atgccaatta tgataaaagt tatgttattt
    15841 gtcttagatg agatattaga gacaattgtt ccagatttaa attaatttta aaatgatata
    15901 aataagagca gttttagttg aactgctctt tttagatgtg tttaatttta tgtaagaata
    15961 tgtattttta ttaatcagct atatatgagc aacagtagtc aacaacttca ttaaccttta
    16021 agtcaaaact tgaatcacta ggaacattaa atttttgccc ttctttataa gttacaaact
    16081 cattgcttcc aggcagtttt acatccatac ttccagcaag catctccatt atttcttctt
    16141 ctctagtaga aaaagtgtat tctcctggca acattaatcc taaagttttt ctttctccat
    16201 taggcagtat tattactctg ctacttacct taccatcaaa ataaacgttt gccttcttta
    16261 ctgcagtaat attcttaaat tcactcatta gataaaacct ccaaaattat ttgtacatat
    16321 atattatata aaaataatgt aaaaaatgct atatatttac aaaaaaattt agtatttatt
    16381 aaaaaaatta ataagaataa aaaagagatg aaattgctta aattgataaa aaatataaaa
    16441 taaattgcaa agtaagcaag aaaagaataa gttgaagagt tatatattat aaatattaaa
    16501 aattttagta ttaataaaaa agatattaca ttaatatgaa aatataggag attagaagtg
    16561 tttgataatt acagtacatg ttagatatat cattgtaaat taacatagct ttgaatataa
    16621 taatgttcag aaggcaatat ttttgaggtc tgaatccaat aataatatag tcttatgatt
    16681 gtagatatca aaaaatgtaa gttactagga atacgttttg tagatttata tatgattaat
    16741 aactaaagct ataaataaac aaaataaaaa gagtatgttt caacctatag cttttagatt
    16801 taaaatatac tcttttatta attatagttg tataaattaa ccataatata taattaaaat
    16861 ttttattata attatatatt aggttcttca attagttttc cacatacata tctatgaatg
    16921 atatttctat catcaccaac atatataaat ctttcaagtc tttcaagtat agaataattg
    16981 tcatgattta aatttgaatc atcaataatc aatgcatcaa aatcataacc ttcttcaaag
    17041 ctaccaactt ttccaaagaa acttccacca cttttggttg caatataaaa agcctcagat
    17101 aaagataaga aattatactt cttaccagag ttaacccaat ataatttaga taattgtatt
    17161 gcagatacca ttgctttaaa tattgacaat gtatgtccac cacttatatc tgatccaagt
    17221 gctaatctaa tattattatc gattaatttt ctgataggca tagcaccact accaacatta
    17281 aagttagaag ctggacagtg aactgccata acattatttt ctctcattaa atctatttca
    17341 tcctgagaac aatgaacaca atgagccatt aaagtaggag tttgaccaaa taaattatat
    17401 ctattatatg catctccata gaatttagat tcaggttcta gacttctaac ccattcaatc
    17461 tcatcataat tttcagataa gtgtgattga ataggaatat tatattttaa acataaatct
    17521 cctaaacctt ttaaaagttc acttgtacag cttggtataa atctaggtgt tattattggt
    17581 tttacaatag aatctgtatc actatactta tttataattt cttctgtatc agtaatagaa
    17641 tcctgagtgt tttctaataa agtatcaggg caattcatat tcatatttac tttaccaacg
    17701 tatgctccaa gaccaacttc tttgaatata tccataagtt tcatagaggc ttctttatgt
    17761 actgttgcaa acactgctat tcttgtagtt ccagatttcc aaagttcttt tacaaatttt
    17821 ttatacattt ttgttgcata ttctatatct ttataatttg attcttctgg aaatgtataa
    17881 gtttcaagcc atggcaaaag ctctttatcc atagccattc caagattttt aaattgagag
    17941 gcatgggcat ggaggtcatt cataccaggt attataagct tatcagtgta atctactact
    18001 tttaggtttt tgtattcctt aggtatctct ttaaatattc cctttacttt acctttttcc
    18061 agcataatat aactattttc aaatactgtg aaagtttctg aagtttttgt aaaaattata
    18121 tttcctttta gtacttttaa catataggtc tccttagttt taaatttgtt ttaatatatg
    18181 taggtaaaat tttgttttac aaatcaaaat tttaccacat gtattatatc aaatctaaac
    18241 tataaatact attagataat agcaaatatt agtgaaatac agttgtttac tattattata
    18301 tataactgac atttaagtga catttaagaa aaatataatg cctacttaca taaaatggaa
    18361 tgttatttaa agagaacttt gattatattt tcagaagttt ttttatccat atcgtttaaa
    18421 acaagaaaat atctattcat agttattttt atattagtat gtcctaatct ttcagagatg
    18481 atttttatat tagttctagc tagaagaaga actattagaa tagataatat agtaagtatt
    18541 tacaaatatg taggtgttct taaattgata aattattcca ttttaatttt atagtttgaa
    18601 ttttatgata taataaaaat atataaattt tgcagtgagc gatatttttg ataaagtagg
    18661 gtttaacagt tgcaatgtaa gggattgagg gtgtatgata aatgttatca attgcactac
    18721 tcatggttca ctgcaaattt gagagagttg tatgtgtgta agtactgaaa atacttagtt
    18781 tattttgggg ttttatatta actaagtggt atgtaaattg tcaataaata aaattttaac
    18841 ttctgtttct ccggtgtttt atattaacta agtggtatgt aaatgctact agaccagcta
    18901 ccactaacag tacgaatgag ttttatatta actaagtggt atgtaaatat agtataaaca
    18961 ctttcaaccg tccttgaaag tgttgtttta tattaactaa gtggtatgta aatttactta
    19021 gaaacaaata tattgttatt aacataccaa gttttatatt aactaagtgg tatgtaaatt
    19081 taagagcatc ttctatacct attttaaagt ttactgggtt ttatattaac taagtggtat
    19141 gtaaatttgc tatctgagta ttaatttctt ctatttcttg cctgttttat attaactaag
    19201 tggtatgtaa atattataat atgtaactat atctaacttt tatattatcg ttttatatta
    19261 actaagtggt atgtaaatgt atgtctttta aagttgctaa tacaactgtt gggtcgtttt
    19321 atattaacta agtggtatgt aaattgaata tcactacacc aaatttttag acattcaaac
    19381 gttttatatt aactaagtgg tatgtaaatt aattagtggt gttataagac tcattttttg
    19441 attttagttt tatattaact aagtggtatg taaatttgac ttactatgta ttacttctaa
    19501 gttacttata tcgttttata ttaactaagt ggtatgtaaa tcaagatatt tttaataaaa
    19561 tttctgagcg aactgttttg ttttatatta actaagtggt atgtaaataa aaatagaaca
    19621 aattatggaa aaatactagt aaatgtttta tattaactaa gtggtatgta aattctcatc
    19681 acaacactat atacatagta aattaacata gttttatatt aactaagtgg tatgtaaatg
    19741 catgttaaag tggctaattg gaactatgat tacagtttta tattaactaa gtggtatgta
    19801 aatagtccag accctaatcc tcctgttgac ccagagtttt atattaacta agtggtatgt
    19861 aaatatagtc aaaagcaaca tcataatcac gtatattatc gttttatatt aactaagtgg
    19921 tatgtaaatc aacatgtcag taatattgaa acaggaaatt cgagtgtttt atattaacta
    19981 agtggtatgt aaataacact ttaaaaacta atgtattcag tataagagat tgttttatat
    20041 taactatgag gtatgtaaat cttgttaatg caaataaaca acatagcact attaatagtt
    20101 ttatattaac tatgtggtat gtaaatttgc aacaagtata ggtaaaatac cccaataatt
    20161 tatacagcat tttctccttt aaaatataat tattttttag catttgtagt aaataattac
    20221 cagataatat tgactttagt tttaatgatt aaaatataaa agtagaataa ttataaaaag
    20281 tattgaaaaa tttataaata tatataataa aacttaatga caagatatta gatataaaaa
    20341 ataattacct tataaataga ttgaaattta tgaatattca tactataatt taaatataag
    20401 gagatgccct ttgaaaataa aaattaaaaa atatttaatg ctattacaat aggaactaga
    20461 actacactta ataaatatac agaaattaga tttggctcaa tataaaatac aaatatagaa
    20521 tttaggtgtt ttttatgaaa aaatttttat atgctttata tagtttcatt gttattatag
    20581 ctaattttag attaaaagaa aaaaattata actttatttt attagcaatc ttttttatat
    20641 tgctgttaat tcaaaatgga gttttaaaaa caggttatca aaatagagct acattttatc
    20701 aagataatta ttttaataga gaggataaaa atgataagat aaaatttatg actataaaga
    20761 tttttatatt tttgtcatta ccattatgtt ttaatatact attcaattat ttaacctctt
    20821 aaattatatt tagatatagg agtcttatga taaaagtaag cttatgtgtt atttgtagta
    20881 aatataaagt gcatatagtg ataaaacaaa agttttatat aaatgaagaa aaaaatataa
    20941 aataatttat ttaactactt aaaaataaac taaaagggat aataaaatag cttttaggtt
    21001 atggtaataa aggtatttaa aaagagtgca taagcactcc aattgtgaga aatacataca
    21061 caaatcatta ttacaacaat gaaaaatgta catataagag acgttttgta tttgttttaa
    21121 gtgataatat tttaatacta actaaataat tatcacaata gtaaaaaaga aaaaggagta
    21181 ttttgtactc catttgtcaa aaatataaaa cttttatata agcttattat aacataattg
    21241 ataaaagtgt aaagatatat aatgaattta taaagaaaaa taaaataaaa aagataaatc
    21301 ctaatcaaag gatttatctt tttgtataga aaataattat tctattatta aatggcatga
    21361 ctaaactgga taataattta ttattactgc tttcaatgtt ttttctcctt gattatggta
    21421 tgtatgaatt gattcagctg aaaaacaaat agagtcattt tctctaagtt gataaataga
    21481 gtcatttact tctaatttta attgaccttc tataatcata atatattcct gtgatttttc
    21541 agaatgacca acagatgtat aactatgacc ttcttctaat tccatttgaa ataattcgaa
    21601 gtttctagtt ggtgtattgg gataataaca ataaagacga taatctttat tttctgaaac
    21661 ttgtacatct atatcagttt ttgatacaat aaaagtttca ttttgaggtt gttccagtat
    21721 tgcagtatat ggaacattta gtccacttgc aattttccaa attgtgttta ctgttgggtt
    21781 tgagtctccc ttttcaattt gcgaaagcat tactttactt acgccagata attcagcaag
    21841 ttgacctaga cttaagttac gttcattacg taatctattt aaatttttag caataacagt
    21901 attaatactc atagtaactc cttaaaatgt aaattattga caaatataat ttacgaatgt
    21961 ataatttatt taacattatt tataatttac aaatgtataa tataatgaac gttaaatata
    22021 ctgtacatcc gtaatataaa ttatactgca taaagagttg tttttcaacg gatgatagtt
    22081 gagagattaa gggggaattg taatgcgtgt acttaataat gttacagagg ctataggcaa
    22141 tactcatatg ttacatttat ccaaaatagc agatgaattt ggagttcaag gtaatattta
    22201 tgcaaagatg gaatacttaa atccgggatt tagtaaaaag gaccgtgtag cattacaaat
    22261 gattaccgaa gcagaaaatg caggtttatt agttccaggt caagcagttg tggaattaac
    22321 aagtggtaat actggaacag gactagcaat agcttgtgca tgtaaaggat ataaatttat
    22381 agcgtgtatg tcaaaaggaa attctatgga aagagcaaga atgatgaaag ctttaggtgc
    22441 tgaagtagtt cttgtagacc aaatgcctaa ttcagttcat ggacaggtat ctggtgaaga
    22501 tttggcactt gtagaaattg aggctcaaaa aatagcaaaa gaaagaaatg catttagagc
    22561 agaccaattt aatttagaag cttgtaatca tgcacatgaa aagtatacag cagaagaaat
    22621 gtgggaacaa ttggatggaa atattgatgt atttgtagat tttcttggaa gtggtagtac
    22681 ttttgcagga tgttcaaaaa cacttaaaaa acataattct tctatcaaat gttatgttgt
    22741 tgaacctgaa acagcagcaa tttattcagg taaagaaata actgaccaag ggcataaaat
    22801 acaaggtgga ggatattcta tggatttgcc attagtagac aagaaactta ttgatggtta
    22861 tattcaagtt acagacgagg aggcaactga tgtagcaaga aaattagcta aattagaagg
    22921 tgtatttgca ggattttctt caggggcaaa tgtatgtgca gcaattaagt tattaaagag
    22981 cagtgaaaaa ggaaaaaata tagttttaac tcttaatgat agtggtttaa aatatttaag
    23041 tactgattta tatgaagaat tgtaataata gcacaatagt tatgcaatgt tttttaaatt
    23101 aagtatatag atttaaatta taaaaagtat ctcaatgtaa tttttgaaag ttataaagga
    23161 gatacttttt tattttgtaa atatggagta tcctacttat aagtattaag ctatatagat
    23221 attgatgatt agctatgcaa taaaaaagag tatgtgtttt tgcatttata catcataact
    23281 tggaataata catattaatg ttctaaatgt atttaaaaca tatgataaaa ttagaacaaa
    23341 tagatacaag gagataaaaa tgcaaaagag aattttaaga aattttatat ttacgggtaa
    23401 aaatatttta agtaaacttg tttttataat aaaatataat tttagtacat taattttatt
    23461 tgaattattt cataaaggat tagccttatt ttttatatgg ccatctatta gatatatatt
    23521 tgatatttta ataaaaagtt tacatatagt ctacctaaat atggataatt ttataaaagt
    23581 tttgaccaat cccatgtcaa tagttctgat aatactatca gttataatac tagcttttta
    23641 tgcatttttt gaatttacct ctgtaattat ttgttttaat aaatcgataa aatatgaaaa
    23701 aatagggtta tttgaactct ttaaaatatc atttgagaac tctataaaat tgttatatcc
    23761 taaaaatata ctattattta tatttgtgat attaataatt ccattagtaa atacagtttt
    23821 aatttcaggg tttataggaa aaatacaaat accagagtac atactagatt atataaagtc
    23881 tgatataatt ttaaatataa tctatatgat ttttctttta ataatatata tttcggttat
    23941 tagatggatt tttagcattc atgagataac tttaaataca gaaaatttta aaagagcaag
    24001 aaaagaaagt gttaatctta taaagggaaa gattataaga acaattattt attcattaat
    24061 attatcttta gtagtagcta ttattggata tgcgatttat tatagtggaa ttatatttat
    24121 aggcatatgg actaaatatt gtactgatat ggaatttttg aagaatgtat ttataaatag
    24181 atgtattgca tttgaagaat attttagatt gattttgtca atattcattt ttatattgga
    24241 cattggattt atctcagcaa cttattatca atataaagga gtaagtattt ctaaaaataa
    24301 tattaaaaaa gagaaaaaat ctatatcaaa aattgttttt aatttagtat taatattatt
    24361 aatttcttat atagagtcag ttgcattttc ttcacatata aatggtatgt ttaatacgtc
    24421 attttcattt tatacaacag caattgctca tagagcagga gctgaaatgg ctccagagaa
    24481 tactttggca gcaatagaag aagcttcaca tgctaaagct gattatgcag aaatagatgt
    24541 tcaagaaact aaagatggag aacttattgt acttcatgat tcaaacttta agagaactac
    24601 aggagtagat aaaaatgttt gggatgtaaa ttataatgaa gtaaagacat atgatgcggg
    24661 aagcttttat tattatggaa aaggttatta tgatgaaaag tttgttgggg aaaagatacc
    24721 aacactcaaa gaaatgataa aatattctaa aggtaaggtg aaattattaa tagaaataaa
    24781 acttaatgga catgaaaagg gagacgtagt aaaaaaagtt gttcagttaa ttaaagaaaa
    24841 taattttgaa aatcaatgta tagttgcatc tatggataaa actatattac aaaaagtaaa
    24901 aaaactggat gagaatttac tgacatgcta ttttatggca attgcatatg gtgatttttc
    24961 aaagttaaat tatgttgata tatatggaat tgaatcaact tttgttaata aaacagtagt
    25021 agaaaagatt cataaaatga acaaaaaaat cttcgtttgg actgttaata gtgacagttt
    25081 aattgagaaa atgcttgacc taaatgtaga tagtattatt acagataatc cataccttat
    25141 agagagtgca atttattgga agaaaaatgg atttattagt caagtgtcag attatttatt
    25201 ttaaatattc tataattgta ttatccagta aaagagatat tattaaaatc aataatatct
    25261 ctttttaaca taaataaggt tgttaaatta aggttattct tataaaaatt gtgcttatca
    25321 gctataaaca aggaataaaa gtgaaaaaat tgatctgaga ttattacagt taaaagagtt
    25381 ttaagatgac agagagatag attgtcaact gtatatttaa taaatcttgt tatttattaa
    25441 attttatata agtaaaatat ataaattaat aaatcttatg ctagaatata tatgaaaaac
    25501 aatataaatt tggaggatta aaaacatgac agagcgagaa aaaatgttgg caggagaact
    25561 ttacgattgt ggtgatattg agttgttaac tcaatggcat aaagcaaaag acctagtaag
    25621 agattataac caaacagatt cctcggattt ggaaaaaaaa gaaaaaatat taaatgagtt
    25681 acttggtggt aagggtaaaa acttatggat tactgcaccg tattatgtag attatggaaa
    25741 taatatttat tttggaaata attgtgaagt caatatgaat tgtacgtttt tagatgataa
    25801 taaaattatc attggggata atgcactaat cgcaccaaac gtacaaatat atactgcatt
    25861 tcatccaact aatgctggtg atagatttgg taatgccaaa gaagatggtt catttgaatt
    25921 ttgtaaaact caaacagctc cagttactat tggagataat gtttggattg gcgggggtgc
    25981 tattatcatg ccaggtgtta ctattggaga taatgtagtt ataggtgcag gaagtattgt
    26041 tacaaaagat attccaagta atatgattgc atacggaaat ccatgccgta ttattcgaga
    26101 aaataaataa agttaaattt tcttgcaaaa tctcaaaaaa cacctttctt actttataca
    26161 tagggtattt tctaatactt tcacatccat attcatttgt taaatttttg tggaatgtag
    26221 tttttatcac ttctatctta catttccacc attttttata aaagtcattc ctttatagat
    26281 ttatttataa tagtatatat tctatttgat gtttgaataa gcacttattt ttaagtaaaa
    26341 tactaacttt taggttagta ttttgctata gtatgatgat taagtaagaa taaaatacta
    26401 taatacataa agcttaataa atataatttt tattttactt agatattttc ttttgattag
    26461 caatcaaaag tagttataat ttttttaatt aataagagta acatttattt tatgaaagag
    26521 gattatatta atatatattt aaataggaaa aattgtaaaa agcataaaaa taatataatt
    26581 aattaatgag ataaaagtgg ataaaaatat tgggagttta atttttgtga aattaaaaat
    26641 attaaagtta atctacaaat atagaatata ttctaagacg aatttttata attactaaat
    26701 aaaataaatt aatcaatata gttttttaat ataaacaaaa aatgaaaaac ttatataaat
    26761 aaaatgcttg tttttcttgt attatttata taaatattga aatttgtcta gttatacgtt
    26821 tttattgacc agttatgcag ttgatattga atattctaaa tattggtgtt attttatagg
    26881 tggtttaaac atattagggg gattttatat atgatttgta tgatttatag agaatgtata
    26941 aaatagtaaa ggtttagagc catgtttagt ggattgcaga atatgcatat agaatgattc
    27001 ttgtaaatta agttagacat aggaaatata taatttgtat tggatgatta attttatggt
    27061 gtatgctttt aacttctata atgggaaagt aaagatgtac tcccaataca tctttacttt
    27121 agcagaagtt atagttactt ataaagtaca aaaaattata tatttattag agtagataaa
    27181 tctaaaaagg tttttctaga aaaatttagt tttaattgta tctacttact aataataaga
    27241 cttgatgtaa gcaggtttca actaccgttt ctccatattc tgatataaaa tcatctaact
    27301 gtgtatctaa aaaattacaa taatcatatg aactactgat gtaagcagtt agtatatgtg
    27361 tacatttgtc tatttctcca ataaacatat tatccatccc cctaaaaaat ttagtaaaaa
    27421 taaaaagtcg cattctatta gtcaattaac ataatttata aaatttttta gtactagttt
    27481 ctataactta actccttaag gttaaatatt cccagtttta ccaatttagt tttattctac
    27541 aagtatataa tactagaaga tgctccatta ttcaacatgc ttgtttgaga atagaaaata
    27601 ttctaaaatt ataattgttt ttaaaaataa gattcaagat aaataaagtt atatgcaact
    27661 atttaataat ctttccataa taaggacagt aggttctatt cttaaaaaac tccatcttta
    27721 aatttaaaga ataactacaa tttgaacaac aataaaattt ccaatcaata aaaatatcaa
    27781 aaataataaa aataattgaa aatgtataat ttcccagaaa aataataaat gtaactccaa
    27841 taataaacac acctataaat tataaaataa tttaagcttt atttaaggtt agtattatat
    27901 ttatataaga tttaagtttt aatatatatg tgtaattaaa atgatttagg aggagaaata
    27961 tattggtaaa ttgggaaata aaaaaattgg ctaaatctaa gagtatgttt atatctctag
    28021 ggatattagt gttaatacta atgattagta tctttattac gcctgtttta gaaacagaaa
    28081 gttattatat agataaagaa aaaggacgta tagaagatac gagaagtggt atagacatag
    28141 gtaatgagaa atttcaaaat aagattaatg ttttaaagca gttttcaaat caaacagata
    28201 caggtgaatt ttctaaaaaa attgaattaa tgtcaaagaa aaaacttgat aatctaagtg
    28261 tgaatgaata taaggatatt agtttttgga aagtatttaa ctatagagtt acaaattcac
    28321 ttataaatgt aggaatgtta atcattatat ctataattat atctaatatt tatgtagatg
    28381 aagtcgttac ttcggtaaaa gatatcatac tatcatcaaa agagaagaaa aaagcattaa
    28441 agtctaaaat atttgttgct ttattagttc cattagtaat ttattctgtt tatttaatgg
    28501 gaatatttat tataacttgt atgcaacaag gagtacctgt taatggagac ttagaatctt
    28561 ttagaatagt agacaatgta gttgcattga aaactaattt aagtataaca aagtatgtaa
    28621 tattaaatat aggcatagag cttttgatgt ttgaaggatg ggccatgata gccatatttg
    28681 ggtcttttat aagtaagtct tcaatatctt caataagttt ttttatattt attatatcta
    28741 taactaagat aatgtcggta atccatatat tacctaaaaa attactttca gttgtatcaa
    28801 atgtaaatta ttatgatttg atatttggtt ttaataaaat aataggaaat tatctaggtg
    28861 atattatgat atttaaagtg aatatagaca ttgtcaatat agcaatagga cttttgatgg
    28921 caatattgat aggtgctatg tcattatgtt ttttagtaat aaaatcagat tatataagta
    28981 gataaaaggg gagttaatat gaataaatta gaaatagaaa atctttcaaa gatatatggt
    29041 aaaaaagtag caaacgacaa gattacagta actctggaaa atggagttta tggtcttcta
    29101 ggaccaaatg gagcaggaaa atctacatta atgaaacaaa taacaacgtt gataaaacct
    29161 gatgaaggtc agatacttta taatggtgag gatatattta aaatggatgc tgattataga
    29221 aatattttag gatatttgcc acaagaattt ggagtttata aaaattttac agcaaaagaa
    29281 tttttacagt atattggagc tttaaaaggt ttaaggggaa aatatttaaa tagtaagata
    29341 ggagaattat tagatttagt aggtctttat gatgtgagaa ataagtctat aggaaaattt
    29401 tcaggaggta tgaagaggag agttgggata gcacaagttt tactaaacga ccctaagata
    29461 atagtccttg atgaaccaac agcaggtctt gacccacaag aaagagctag atttaggaat
    29521 ttaatagcaa aaatgtctag agataagata ataatacttt ctactcatat aatttccgat
    29581 atagaatcag ttgcaaagga aacaataatg attaaagatg gcaaacttct aatgaaagga
    29641 acacacaaag acatattaag tcacatggaa aataaagtat ataatgttca agttaaaaat
    29701 gaatgtgaag ttgatgatat acaatctaaa tataaggttg taagtattca aagtgatatt
    29761 gattcagtag tacttagaat tgtttcagag gatattccaa gtggggataa tatacaatca
    29821 gttcaagcaa aattcgaaga tgtatacatg ttttattttg atttggaaga tgcaagggag
    29881 gtgtagtaga aatgatgtat ttagttaaag ctgaaatgat aaaaatatta aaatcaaaga
    29941 gtgtttggat aatttggctg tttttaatat tttttggatt ttttctgatt agaaagtttg
    30001 atgttttaga tacttatgca gatatatttt acaagataga aggctcaata cctctaatag
    30061 gtttgataat gtttataata acttctggaa attacattaa agaatatgat tctaatatga
    30121 caggtttaat aaatacaact aaaaagggaa aaaaatcagt agtattatca aaactagtag
    30181 ctaatggatt aattttatct attattaata tttcttttat attgttagta ggaattagag
    30241 gttttagttt ttttgatttt aaaaatttaa atgaatcgat tcataactta tggtactttg
    30301 gaaatagtaa tttaaatctt acagtaatac aaatgtatat aattgttata ttgactacta
    30361 tttttgcttc ttttatattt gcacaaatag gcttaacact ttcatctata tttaaatcgg
    30421 ctgtaattcc atttatacta ggtggattga taatggcaat tccatacttt agtgtaggtt
    30481 ttataccaga taaagctata aaatttatgt cagtgactcc aaattggatt atgatgagcc
    30541 aacaaatggt taagtataat gtaccaagta ttttgatagt tttttctata gtaatctcaa
    30601 ttatattaat gatagtgtta actaaaataa cgtatgaaaa ttttacatca agcaaaaggt
    30661 tttaaccaaa aataatagta attttatttg tattttagtt taattaaaaa taagataaat
    30721 gaattttaga taaaatatat gctaatatat atgtaaatta ttacaggagg ttgtttatgg
    30781 aaaatcgtgt tttaataata gatgatgaag tagaaatatt gaagctttta gaaactgtcc
    30841 taaaaaaaga gggccttaat aatatatata ctgcaaaaac taaaaaagaa ggattagaat
    30901 tatttaaaag tattaatcct gatttgattg tattggatat tatgttacca gatggcgaag
    30961 gttatgatat ttgtaaagaa ataagaaaaa cctccaattc tccaataata tttttatcag
    31021 ctaaaaccga agaattagat aagttacttg gactagcgat tggaggagat gattatgtta
    31081 caaaaccttt tagccctaag gaagtggctt ttagagttaa agcgcatttg agaagattaa
    31141 gttattttag tgatgctcaa aacgaaagta aaaatctaaa taataatgaa gaaaaaatta
    31201 tatcatttgg cccatatata ttaaatgaaa gtagggcaga acttataaaa gatggaaaat
    31261 ctataggact gtctgcaaag gaactaaaaa tcctatcttt atttgcacat aatcaaaatc
    31321 aaattataag taaagaaaaa ctatgggata aagtgtgggg agaagattat gttggatttg
    31381 acaatactat aatggttcat ataagaaaag ttagggaaaa attagaggat aatccttcaa
    31441 agcctgaata tattctgaca ataaaaggtc ttggatataa attagcagta aaggaagatt
    31501 agaatatgaa gtggaagatt actagaaatt ttatatttac aattgtgttt gtagctatat
    31561 cagtagtaat tataaatatc atatctatat tgtatgtgat ttcaactaat agttttttta
    31621 aagttgtaga ttctggaaat actcctgaag aatttgcacg ttcttttgaa aaagatttat
    31681 atgaaaaaga tggagaattt aaactatcta agattggagc tgaaaaatta gaaaaatcaa
    31741 attcctggat acaggtttta aatgatttag gagaggaagt ttatggagta aatgtgccaa
    31801 aggatactcc caaaaaatat acaccctttc aaatggtgaa taattacaag tatatagaaa
    31861 caaagtatgt taattttgta ctagaaaaat atttaaacaa aaaacatcta aacataatag
    31921 taggtatacc tagtagagat atatcaagaa taattttaac ctattctcaa aataacatta
    31981 aaaaaacttt aaataaagtt atcattataa cactagtaat tgatagcgtg gtagctttag
    32041 gtgtaggata tttatttagt agaaaactta caaaaccaat ttcaagcgta ctatggagta
    32101 ttgagactat ggctaatgga aattatagtt tatatcttaa ggacagaggt atatatgaag
    32161 aagtttttaa aaatataaat atgttagctg atactttaag agtaaatgaa gttgagagaa
    32221 aagaaaatga agagttgaga gaggaatggc tggcaaatat aacacatgat ataaagacac
    32281 ctctagcatc tatacaaggg tatgcagaga taattaatga caaagattat gagtttgaag
    32341 aagatgaaat acaagagtat acagaaatta tatataataa gtctaagtat ataaaagatt
    32401 tagttgatga tttaaattta tctactcgat taaaaaataa tactatagtt ctggacaaga
    32461 aaaaaataaa tttagtcagt ttagtcagag atataataat tgatatttta aatgataata
    32521 gatataaaaa taggaatatt gaatttgaaa gtaatgaaga tttaattgaa gtatatgtag
    32581 attcaatctt attcagaagg gctataacca atcttatatt taattcaata gttcataata
    32641 gcgaaggaac tttgataagt gtagaaattg taaaaaaaga taatatagaa attataataa
    32701 aagataatgg aattggaata agcaaaagtg atttgaaaca tatttttaaa aaatattata
    32761 gaggtactaa tacaggtgag atgcataaag gttcaggtct tggtatggct atttctaaag
    32821 aaataataga gattcataaa ggtaaaattt atgtaagtag tgaaattgga ataggaacaa
    32881 aaattattat agagataaaa caaaattagg agatatgata tggatttttt aaaaaaaggt
    32941 ataagtgggt ttactattaa gattttagca ttaatattta tgacatttga ccatatagca
    33001 gtatttatgc cacaaacaat gcaaatacca atttggtttc attgggtagg cagaatatca
    33061 gcaccactgt ttatattcat ggctgttgaa ggattttatc acactagtaa cagaaaaaaa
    33121 tatataagta gattgtatat ttggtctgtt attatggcta taggaaatca aataattaat
    33181 aatgtatttt cacatccaga aggagctata attataaata acattttttc aacattattt
    33241 ttaatagcga tttatttaca agcaatagag ttcataaaga aatttagaaa agagaaagaa
    33301 attaaatatt ttattatagg attattgatg ataatcattc ctataatttt aggaatattt
    33361 acagtagctt tactttttaa agtcactaac agagttattg ctttatttat gattttggta
    33421 ccagtaccat ttttagtaga aggtggacca atttggatta tacttgggat tattttttat
    33481 ttgtgtagag gtaaaaagtt cagtttgagt atttgttatg ttttaatgtg tatatttata
    33541 tttacaacaa tgtcaaatgg agattatagt ttaaaaaatt ctattttaca aaattaccaa
    33601 tggatgatga ttgcttctct acctttaatg ttactttaca atggagaaaa agggaagagt
    33661 atgaagtatt tattttattt atactatcca atccatgtat atatattgta tatcttagga
    33721 atatacttaa taaatggttt ttgattgtaa gtgatatttt taatacaaaa tgaacaatat
    33781 gaggattgtt ttaggtctat taaaattgtt atttagatga gatttgtaga atatttaaat
    33841 ttatgagcag aaattcagtt attgtaattt caataacatt agaatataat attataattt
    33901 atttagaaat atatgatgtt atatatggtt tggttattaa tgtaataata aaacagaggt
    33961 ttgatataaa attcaatacc tctgttttag tgctttttat cctacattta tgcttatttt
    34021 atttataaat tagtgttttg ttttaattaa tattagtgca ttttttattt attttataaa
    34081 attagtcata attgtttctt catattgtgg ttctttaatt ccagcttttt tacctgctga
    34141 tatacactta agaagccatg ccatgttttc tcctagagtt cgcatagtct gtaatccttc
    34201 ttcatccttc ataacatcct ctggagtaaa gccatgtacc tggttccaat actgtgatga
    34261 tacaataggc atattgctga ttgaaaaata tttatttagt tggtcaaatg ttgcacttgc
    34321 accaccacgt ctacatgaca caactgaagc acctaatttt gtagccatgc gactcccagc
    34381 tatgaaaaat aaacggtcaa gaaaagaagt taattgacca gttgcactag aaaagtaaac
    34441 aggagaacca ataataatac catcaatatt atccagatct tcaatcaatt cattaacttt
    34501 atcatttcga atacattttc cagtttcaaa acaggatgcg caactaatac atcctgggat
    34561 tgtttcttta cctaaataca gtatttctgt tttaatatcg tgtttactca atactttagt
    34621 aatctcattt agtgctgtat aagtacatcc atattggttt gggctaccgt ttatcaataa
    34681 aactttcatt ataaatttcc tccaatgaat tttatttaat agattttcta agagacatta
    34741 ttttttataa aataggattt tcatgaatat tatcaattta tatagaaatg tctaatctta
    34801 gaatcctatt taaaataact tttttttagt aaatacacct cctattataa aattgacttt
    34861 caattattct tacactataa ttttattata aattattcta aaaacaagta cgcacatttt
    34921 tgttcaatac taaccaaaag gagagtgtaa tatatgagta tagactgtat atcaaataca
    34981 gatttaagtg aaacaggatt tagttataca ctttcactga ttagtggtaa atataagatg
    35041 ataattcttt actgtcttgt agaatttgaa gttgtaagat ataatgcatt aaaacgttat
    35101 ataaatacta tctcctataa aactttgagt ttatcattaa aagaattaga agcagataac
    35161 ttgattattc gtactgaata tcctcaaata cctcctaagg tagaatatag tctatcagaa
    35221 aggggaaaat ctctgattcc aattttagat gcaatgtgtg agtggggaga gaggaataga
    35281 ccttaatttt gtatctgtag ataccataaa aagactgtga gtaaaattgt ttgaataatc
    35341 tactcacagt ctatatttaa attaatagtt agtattttta atttataaaa atactaaaaa
    35401 atttattatg aaatttcacc accaatttct tttacatctt ctttatatat aatacaagct
    35461 tctatagcta attctaagcc ttttactatt tcttctaaag acatgaatgg tgtatttttt
    35521 ttatctatta cttgtgaagt tgtatatggg atgtgtataa atccacccct tatattagga
    35581 tatttcttgt ctatcatata aagaattcca tacatcacat gattgcaaac aaatgttcct
    35641 gcagtgtttg aaacactagc tggaatttta ttttcattca tatgtttaac catagctttt
    35701 acaggcaatt ttgaaaaata tgcaggttca ccatcttctt ttataatagt atctataact
    35761 tggttaccct cattatcttt tattctaaaa tcatctatat ttatagcaac tctctcaggt
    35821 gtaatgtcaa atctacctcc agcttgtcca actgatatta ctatatctgg attgtgctct
    35881 tgaatagctt tatctatagc ttcaacagat tttgtcataa ctgttggtat agttatcttt
    35941 atgatttctg caccgtttat attattattg accctttcaa ctgcttcttg agctgggttt
    36001 attggttctc caccaaatgg gtcaaatcct gttaacaaaa ttttcattat tttacctcct
    36061 aattatatta aaatcctaaa aagtacatta ctaatatgtg ggctataatt aataccaaag
    36121 caactggagc ttgatatttt ataacaatat aatcattttt acattctagc aaggctgctg
    36181 gaactatatt aaaattagca gccattggag taagtagagt tccacaatat cctgctgtta
    36241 atgctaatgc tccaattata gcaggatttc caccttgaga caatacaaaa ggaataccaa
    36301 ttcctgccgt tatgactgaa aatgcggcaa atgcatttcc cattatcatg gtaaatataa
    36361 ccatacctaa tacataagct ataacaccaa ataatctgct atcagcaggg actacaccag
    36421 atatcatggt tgaaataact tcaccgactc cggcttgagt aaataaagct cccaatgcaa
    36481 ctaaaagttg tggtaacata ctagcaggtc ccatttgttg aagtaatctt gagccatctt
    36541 gaactgatgt agcaggtttt gccttagtta ttataagggc tgatattaat gcaattattg
    36601 aacccacacc tattgcaaat tgagaagaat tatcaaaatt agaaaggctc atagctacta
    36661 ctactgcagc aaatgctaat attaatgatg gtataaatat tttattttta agtttatctg
    36721 cttgttcttt tccaaaattt tcatctggtt cttcatactt tgcaaataca acttgtttag
    36781 aaagtgttaa taaactagat aatattaata ttattcctat tatattggct ggaatcaatc
    36841 taccaaatat gaatggcaat gatataagta tccaaaataa tgatgtacca tatttcttat
    36901 tgttatttat ggtagtaaaa gacttatatg ctataacaat cattaaaaat cccattagtg
    36961 cgtaaaagat ttccaatgat atgtttataa aattttgcat ttttattcct cctaaataaa
    37021 actatttttt atgacttttg tttaattttt tatcatataa ggtaaactgg attgtagcca
    37081 ctacaagtgc tattactgcc ataatagtac tagcctttac gatattaagt ccagttacat
    37141 tgtatccaaa ttgagtcaga gtagatgcta taagtaatac tccactacta cctgcaaata
    37201 agttttgacc ataaaaattt ccatagtttt ctgatgcagc agataatgcc tttatggctt
    37261 cttcatccga ttcttttagt tcatcactat tacttaaacc agcagcttgt gccataggat
    37321 taacaagtgg tcttacaaat tgaggatgtc cactcattct tattgataga gcaccagcta
    37381 tttgtctagc tatcatgtat atagtaagta cttttcctgt tgtaagtctt tttaattttt
    37441 ctattaaaga aacagctctt tgttttaaac catatctttc taatacaccg attactggca
    37501 atgttaatat gaataatgat acacctctgt ttgagacaaa agaatctcct aaaattgtaa
    37561 aaatttgatt aaaatctaat cctgcaacaa ttcctgttgc cactcctgct aataatacag
    37621 taaataatgt gtcaatttta agtataaatc caattacaac tatcaatata ccgattagtt
    37681 ttatcataaa ttgttctcct tccatttcta tatgttttaa tttaaattta tttaatggat
    37741 aaagttaaac tctttttata gtatttgcgt taataggact attattataa aatttaataa
    37801 aaaataggga agatgtttta aagtatcaaa gtaaataatg gttgtgtata ggaatttgaa
    37861 taacaaagat tatattttaa gctaatatta attgattttg taagtctata gtttaagtat
    37921 atgtcaatat ttgaaatagg ttttaaatta gatattatat tataaaaaga gaatgtgcca
    37981 aacatagaga caagtgtatt tttctctttt gaaatgataa aaatatattt gatttcatac
    38041 aaaaagagag tgtctaatga attttttagt tcattagaca ctctcttttt gttatgatta
    38101 ataaaacata tattaagtgc tagtttcatt agatttcact aagaaaaata aaattttgat
    38161 aaagtttaaa gactattttg agcaatatta cttataaata aaagaattta tcatagaaat
    38221 aattagcttt attttagcta ttaagattta ttaaaaaatt atctatatta tcctgtgata
    38281 ttctaaaact gtcataatta ccttttgaaa cagccttcat aataagttta tctaaaaatt
    38341 tcattttttc taatcgagct tcactaccaa aaattccaat agcatttgca ctttctaata
    38401 aggatgatgg aaaatttgat tttaaatatt tatctgcttg ttcagaaaag ccacagcaaa
    38461 ggaaaatgcc aacttgtttt ttgtttaata actctacatt atcattacat agcacttgta
    38521 ttttttttga aactgaacca acatatatag aacttccaat aataatttta tcaaattttg
    38581 ataactcaat tttattatta ttattaatat caacaatagt gacattatct gatagtttat
    38641 tttttagtat atttgcacag tcttttgtac aaccatattt acttgaatat ataataatag
    38701 tattcataat tattctccct ttcttaaagc attttctaca acttttcgta tagtattact
    38761 gctataagtt gcagaagtta tagcatccac atctaaagac tgttgtttaa taatacttgt
    38821 tgtaattttt tcagcaggtt tacctaaaag atggtcgtgt tttaagatat taatattttg
    38881 gattttacca ttattaactt caacagacac agtagctttt accaagttat tatcagcact
    38941 tccagtataa atgccatttt taacattatt aatatctata tcttttacta ccaagttttc
    39001 tggctttaag ttgcttacaa ttacaataat aatgcatata aatacaaaga atagagcaat
    39061 agatattttt acatattttt tctttttatt agtagccttg ttgcgaattt tcattgtaaa
    39121 gtcctcccac taaaatatct aagaaatttt ctataagttg agaaaaatta tgtaaagaat
    39181 atagtttatt ttcaacaaca cataaaacga atcctaacaa tgcacttata agcatccatg
    39241 agcttttatc tatatttttt ttgaatattc cttgttcaat tccaatggaa aggaatttat
    39301 caagcatttt tataccatta ttgctaggcg tattgtttgt attttcagat gcaaatataa
    39361 tattcattct actatgcatg atagcttttg ccatctctgg ttcactagaa agagttttta
    39421 taaagctagt cataatttct atgatttgtt tatctattgg tagtgatgag caattattca
    39481 taatgtcaat agcattactt tctactgtgt tataaagttt attggtcata tcgctgataa
    39541 tctctgcttt gtctttgtag taaagataaa ttgtagttgg agaatattct atttttgtag
    39601 caatttttct tattgataaa ttttcatatc catgttggtt tataatttcg atgctagcat
    39661 ccataatctt tttcttcatt tcttcttttt catttttacg tctttctttg atactcatat
    39721 aatcacctct ttacttaacg gtgttaagtt aatttacact gttattgtat aatttaattt
    39781 taatactgtc aataaattat taaataatat aagttaatat atttttatgg ataataaatt
    39841 aatgttatta attgtaatat ttaagatatt attgtataat aataatcggt ttaaatgcgc
    39901 cacatcttat taaagttggt tcataattct aaataaactt taataagata cattaaaata
    39961 taataaattc ttttatgcta taaaatttat tttatagcta ttaaatcaga tgtttaaaaa
    40021 ttttttaaca gtctatagtt tttaagagtc tatagtaagt agcctaaaaa tatgatttta
    40081 catctgtact tgttcgagaa ctccaagtat aaaaaactaa ggaattatat agtggcagta
    40141 tataattaat acccttagac acaccttttt gaaagtggaa aaaagatgtg tagttctcct
    40201 cgaccacaaa tcaaggagga taaaaaatgg aaaagagaaa agtaataatt gattgtgacc
    40261 caggaattga tgattctttg gcaattcttc tggctttaaa ctcaccagag ctagaagtaa
    40321 ttggaattac cacatgttgt ggaaatgttc cagcaaatat aggtgcagaa aatgcactaa
    40381 aaacacttca aatgtgttct tcactaaata ttccagtata tataggagaa gaagcaccac
    40441 taaaaagaaa acttgtaaca gctcaagata cacatggaga agatggtatt ggagaaaact
    40501 tttatcaaaa ggttgtagga gctaaagcaa aaaatggagc agtggatttt ataataaata
    40561 ctttacataa tcatgaaaaa gtatcaataa tagcacttgc accacttaca aatatagcta
    40621 aagcacttat taaagataag aaagcatttg aaaatctcga tgagtttgtg tctatgggag
    40681 gagcatttag gattcatgga aattgctctc cagtagcaga gtttaattat tgggtagacc
    40741 cacatggagc agattatgtt tacaagaatt tatctaaaaa aatccacatg gtaggtttag
    40801 atgtaactag aaaaattgta cttactccta atattattga gtttataaat agacttgata
    40861 agaagatggc aaagtatata actgaaataa ctagatttta tattgatttc cattgggaac
    40921 aggagggaat aattggctgt gtgataaatg accctctagc agtagcatac tttatagata
    40981 gaagtatatg taaaggattt gaatcatatg tagaagttgt agaagatgga atagctatgg
    41041 gtcagtctat agtggattct ttcaatttct ataaaaaaaa tcctaatgca attgttctaa
    41101 atgaagttga tgagaagaaa tttatgtaca tgtttttaaa gaggcttttt aaaggttatg
    41161 aagacattat agactctgtg gaaggagtga tatagtgtga aaagaaaaat atgtgtaaaa
    41221 actattacac ttatagcttt tggtatttct ataaatataa taggcgcttt tatagctatg
    41281 ggattaagat tacctgtata cttagattca ataggaacta taatgatagc ttcactttta
    41341 ggacctaaat acgctgttgt tacaggtgtg tttggaagtt taataagtgg aattacgttt
    41401 gatgtgtatt ctctctattt tgcaccagtt caaatatcaa ccggattact tgctggaata
    41461 gcatttaaaa agaatttttt aaggggttta aaaactccaa taggagtact tttatttgcc
    41521 attccaacat ctataataag ttcaataatt tcagcatttt tatttggagg tatgacctct
    41581 tcaggttcat catatatagt gcaaatcttg aaagtgttag gactgggaga tgtttttagt
    41641 gtgtttgtaa cccaagtatt tactgattat ggagataagc tgttagcagt tgttttagtg
    41701 aatttaggat taaatgcagt tccaaaaact ttaaaggtat cattgactgg aggaaaatag
    41761 atagaaaatg gatagatata gtgagataac aaataaaaat caaagagaaa ttgttctgct
    41821 taaaggattt ccttgtatat ggggaaagtg ttctttttgt gattatatag atgataattc
    41881 taatttagaa gaagagatga ataaattaaa tctaaaggtt ttaaaaaacg taactgggaa
    41941 atatggagtt cttgaagtca taaattctgg aagctgtttt gaattaccta aggatacttt
    42001 agaaaaaata aagtgtatta taaaagagaa aaatataaaa aaattatttt tagaaagtca
    42061 ttggtcttac aaaaataggc ttaaggaaat gagagagtat tttgaaattc ctgtggtatt
    42121 taaaattgga gttgaaacct ttgacaatta ttttagaaat aatattttaa ataaaaatgc
    42181 aaattttaag actccacaag atgtaaaaga atattttgat tcaccttgta ttatggttgg
    42241 aataaaagga caaacaaaag atatgataga taaagatata gagattatcc taaatacttt
    42301 tgaaaaagcg acagtgaatg tttttataaa taattcttct agtataaaaa gagatgaaga
    42361 gttagtgaaa tggtttgtta gtaagtataa attcttggat gaaaatccaa atatagaagt
    42421 tttatacaat aatacagact ttggtgtagg agattagcat taatttagtt taaatttaaa
    42481 attgaaaagt ttcttatgtt tttgaaaaag cttctaatag ttagaagctt tttttgtaga
    42541 gttttatgtt acaataagaa aaaaggaatt aaggagcaat taaatgatgt ttgatagggg
    42601 aaaatggaat aaattggatt ataatgaact tttagaatat atgatgtcta tacaagatat
    42661 aaaatataga gattttaata aaaagcttat acctggaaca gaaaatataa taggtattag
    42721 agttcctaat ttaagaaagt tatcaaaaga aataagccaa ggaaattgga aggaattttt
    42781 agaagtagca gaggatacat actatgaaga agttaggcta caaggtatgg taattggcaa
    42841 tataaatagt aattttgaag aaactttata ctatgtaaaa agatttatac ctaaaatcga
    42901 taattggtca gtttgcgatg gattttgttc tgatttaaag tctatgaaaa aatataaaga
    42961 aaatatgtat gatatactta aaaaatatgt ttattcaaag aatccatggg aaattagatt
    43021 tgcattagtt atgtttttaa tatattatgt tgatgataaa catattaaag aaatatttga
    43081 atactgtaat aatatacaaa gtgaagaata ttatgttaaa atgggtatgg catggttgct
    43141 atcaatttgt tttattaaat gtgaagagga aacttttctc tatataaaaa ataataattt
    43201 agatgatttc acttataata aaatgctaca aaaaataatt gaatcaaata gagtagattt
    43261 agaaaagaag aatataataa gaagtatgaa aagaaagaca agaagatgtt gacggaggaa
    43321 tattaatgaa taacaatgaa gacagaattg acaaattttt agaacttcaa agcaaaggat
    43381 ttaaatttgc agagatagct caaaatctaa agattagtca aagtacttta agaacttttt
    43441 taaataaaaa aggatataag tcagaaaaag gtaaatacat attaaaagac gaattaaatt
    43501 ataataaaag tttggataat agaaacttgg aagaagagaa agctaaggag tatgaaaaaa
    43561 gtaaaaagaa tactataagt aatagaaaaa aagtaagcac caaaaaaaag atttctaatg
    43621 aaaaggcttt aagtaaaagt gttgaacaaa ttgagtttaa tgatacaggt ttaaaaaatg
    43681 caaagccaaa acaaaatgtt aagcctaaga aagatagaaa aataaatata actcaagaag
    43741 atttagataa gctttgtgaa gtatatgatt ggtatttaga agtaaaagat tacaatataa
    43801 agcctaaaaa agtatctaat aaaaaagatg tacatataga tgatgaacac atagatgaat
    43861 taaaaacaac aagaatacgt atagataaag aaatatggaa tgattttgaa agattatgta
    43921 gtaattcgaa ttttgaaaaa catcaaatac ttacacaggc attgaaagaa tttatgaaaa
    43981 agtataaaaa tctactataa aatactacta tatgaggtgc ttaatatgaa taaaatagta
    44041 aaaaaatcaa tttctctaat gattatatta acaatattta tttttatgtt gacagcatgt
    44101 gaaaaagatg aacagcctga ttcagttgat attcaaacag aagataaaaa tgagataaaa
    44161 atagatgagg gaaatgcaaa agtattgaat ataggaaaat cagaaattat aaatatagat
    44221 gaaggtgata aagtagatac atcaacaaag gtagaaaata attcaacatt taatatatcc
    44281 aatgttgaat tgatatataa tgaatatgat gagaataaaa aaattatatc ttcagatagt
    44341 aaggctttgt tggacatgac tttaatgcct gggaaagttg cttacataga atgtgggcat
    44401 aaaacttttg taaagggtgt agaagtttat gcatatgaat atgaggcaga gggtaagatt
    44461 gtgtatgtta atttaaaaga aaatactatt aatataagaa ataataatat taagctagaa
    44521 aatagtagtc agtatgaggt gctatctaca tcagaactta aaaaagtaaa tgaatcaaat
    44581 gagggaatta cgtatcaagt aaaagtaaaa aattcatcat caaaagattt aggaaatatt
    44641 attcttaaga cagcagaagt taatgaaaat ggagaatatt taacagtaaa tcgtgtgcca
    44701 tcatataaga ttttaaagcc ttcagaagag acagatatag atatattgtg ttcaacaaag
    44761 gcaaaaagtg ttgaaatagt gggatatacg tatgatgata taaaagaaaa agccaatgtg
    44821 gatattgact taaaatctca taaagttaag atagacaaat aaaggtaggg gatacttatg
    44881 aaggttttaa tagttgaaga taataagata cttttagaaa gtgtagtaga agaacttagc
    44941 aagcattttg aaactgaaaa gtgtgaagat ggagaagaag ctttatactt agtaaatcaa
    45001 aatatatatg atttagtcat tttagactta atgcttccta atataaatgg atttgatatc
    45061 ctaaagaaaa tgagagttaa taatatagat acacctgtac ttatattgac agcaaaagaa
    45121 acattagatg acaaagtaga agcatttact ataggagcta atgattattt gacaaaacct
    45181 ttttatatgg aagagttagt agctagggta tacgctatat taaggactaa tggaaaaata
    45241 aaagaaagaa acggattaga atttaaatct ttatatttag atacactaga aaaaagagtg
    45301 tatattgaaa aagaagaaat aaaacttcaa aacaaacagt ttaatttgct tgagtatttt
    45361 gtattaaata aaggttcaat tttattaaaa gagcagattt atgatagaat atggggaatt
    45421 gattcagatg cgactattga aatagtggaa gtatatgtaa gtaatctaag aaaaaaacta
    45481 agtaaatatg gatatgataa atatattaaa actaaacgta aggtaggata tatattcgat
    45541 gataaataag aatgtattta ccagtactaa aaatcattta ataaaaatgt atattattgt
    45601 agtaggtagt tttttaataa tcttttctat atttatatac tcatatttta ggggacttac
    45661 atatagtgga attgatagtg agataaatga tgaacttgaa tatatagtct ctcaatttaa
    45721 aagaacttca tttttgaacc caataagact gaaagatcct aaagatatgg tgtatgtata
    45781 tgaagatgga aggataagtt actatactca aaatgaatat tttgatgagt tacttccaga
    45841 tagaagacta gataaaaaaa attcgttttt taaatacaca gaaaatggat atacttttag
    45901 agaattaaat gtagatgtag gtagatacca aatacagata attagaaata tagattctga
    45961 gatgaattct ttaagacagc ttacatctgt tcttataatt ggaatattaa tttctgtaat
    46021 aattacttac tttgtggctg tatatctcac tagaaaagct ttaattccaa tagaaacagc
    46081 atggaaaaat caagctaagt ttatacaaga tgcttctcat gaattaagaa caccaataac
    46141 aatagtttca tcaaaattag aaagtatgtt aaaatcccca gaaagtacag taaatgatga
    46201 agttgaaaca atagctactg caatgaagga aactagaaga cttaaaaaaa tgataactga
    46261 tttattgtct cttactaaag aggactctat tgttaaagtt aatttagaag aaatagattt
    46321 agaaaagtta ttggaagaaa tatcagaaga ctatattgac attgctgagt ttcaggaaaa
    46381 aagattcgtg tttaattcta aactgaagaa taaagttata ataacagata aaaataaatt
    46441 aagacaactt atattaattt tcattgataa tgcctttaag tatacaaaat tgggtgatga
    46501 gatagcatta gaattgaaag aagatataga ggatgaggta actttactta taagtgatac
    46561 tggtataggc ataaaaaaag aagagatacc tcttatattt gatagatttt ttagaagtga
    46621 aaatgtaaga aataaagatt tagaaggttc tggaatagga ctttcaatag ctcgcatgat
    46681 tagtttaaac ttatctattg atataaatgt aacttctgat gtagatattg gaactacatt
    46741 tgaattgtca ataccaaaaa agttaaaata ataaaaatat aaaaaattgt ttttagaaat
    46801 gaagaatggg tatactaatt agtataaaat ataaaaagac cttataaaag taaatttata
    46861 tttataaatt tcatagtata attatatagg gataataaag tttaatagga ggatttaaaa
    46921 atggcaaaag ttataaatac atctgaattt agaagtagtg ttgaaggtag taagggagta
    46981 gttgtagttg atttctttgc aacttggtgt ggaccttgta acatgttggg acctgtattt
    47041 gcagaattag gtgaagagat gaaggataaa gctagatttg taaaagttga tatagatgag
    47101 agcttagaaa tagctcaaca attcaatgta tctacagtac caactatgat tatatttaaa
    47161 gatggaaaac cagtagaaac tttaattgga ttcatgccaa agaacaaaat tgaaatgcaa
    47221 gtaaaatcat atttataaaa aatgggtgag tattatgaga tatgatatag ctataatcgg
    47281 cagtggtcca gctggattgt ctgctgctat aaatgcaaaa ataagaaata aaacaattat
    47341 catgtttggt aatgataatt taagtaataa gcttgttaaa gctccttcaa tagataatta
    47401 tttaggtttt tatgatataa gtggtgatga attaaaagac aagtttaaat cacatataga
    47461 tagtatggat atttcaattg aaaataaaag aataaataat atttatgcta tgggagaata
    47521 ctttacaata atgtctggaa atgatatgta tgaagctact actgtaatcc ttgcaactgg
    47581 ggtagagtat actagaccaa tcaagggtga agaagaattt ctaggaagag gtgtgggcta
    47641 ctgtgctaca tgtgatgcac cactttatag aaataaaaag gtagcagtta taggatataa
    47701 tgaagaatct aaagaagaag caaatttttt aagtgaactc acttcaaaga cttattttat
    47761 acctatgtac aaaaaagata atcttatgag aagttcagat aacctagatg attctattga
    47821 agttatacat gacagaccag tacagataga tggagataaa cttgtaaaca aagtatcttt
    47881 taaagaaaac cacattgaag ttgatggagt attcgttata aaagatagta cagctccaag
    47941 tgcattggtt cctggaatag agattgatgg cattcatatt aaagttgaca ataatatgaa
    48001 gactagtata gatggatgct ttgctgctgg agattgtgtt ggaaaaccct attcttatat
    48061 aaaagcagct ggtcaagggc aaatagcagc tttaaatgct gtttactatt tagataaatt
    48121 aaagagggct taatatttat attgattaac tttttaaaga tatttataaa aaactgtctt
    48181 gaaataattt tattatttca agacagtttt ttatttttaa gttattaata aaagtatttt
    48241 aaaatctata tgtaattact tttattaata aaactcaaag ttatattagt aaaaattgga
    48301 attatttata atatactcca aaatttaaaa ataatggttg aaaaatctaa ttaagagtac
    48361 tataatttaa ttaagtaatt acttaatcaa aacgaggtac ttatggaaaa cttggttaaa
    48421 atatttaaag cattgagtga tgaaactaga cttaacatac ttatattagt atccaagaga
    48481 aatatatgtc aaaaggggat ttctaaatat ctagggattt cagattctgc tgtttcacaa
    48541 catataaaaa tattaaaaga tgttgggata ataacaggat ataaagaagg atactatgtt
    48601 ttatatcata ttaataaaga atcatttaat atatgtgtag attttataaa ttctatgtta
    48661 agtaattcta gtgaaagctt tatagatgta tttgatgtaa atacaataca tctaggatgc
    48721 agtaaagaat gtaaatctat aaaaaaatgt tgtaagagaa gggagaaata ataatgaaag
    48781 tatgtatacc agtagaggag aataaaggat tggatagtaa accatatgga cattttggtt
    48841 ctgctccaat ttttgttgtg tgtgatttag aaagtggaga agttaaatct ttagataatg
    48901 gagatttaga tcatgaacat ggaaaatgtc aaccattaaa agcattgtca gggacagctg
    48961 tagatgcagt agttgttgga ggaataggac aaggagctat aattaaatta aatggaatgg
    49021 gaataaaagt ttacagagca gaaggtgata ctataagtgc taatttagac ttacttaaaa
    49081 atggaaaatt agtagaattt ccatcagacc atacttgctc acatgacgga tgtggacatc
    49141 attaaaaaaa acagctgatg aaatatatac ttcatcagct attttttctt ttaataaata
    49201 cgattttatt cttttaaaac caaaatttag atttttatgt tttttgtggt atccttaata
    49261 atatttcaag tttacaagtt tactactttt agattttttt tgtatgtttt tctatatagt
    49321 caatatcatt taatatgtca ttgagttctt tattaagtgt ttttaaatca tcaccatcta
    49381 cattgtagtt taaaaatagt tcctctacat tatcaatgat agaattgact tttctagtaa
    49441 cttcaacaaa tgtcttaaag ttactactat ttttagcatt tagaaatttt tttaaatcct
    49501 ttgatataaa tgatactatt tcatattcat cattaaatag acctctacca ataggatatg
    49561 gttcaattct ctgtaaaaaa tattggtctt tagcattaat attataagta taagatattt
    49621 cccaaccgtc tcctaaatca aacttgataa aatataatgt actacttact tttgatattc
    49681 ttgtggcacc aagctgtctt aaaagaactt caatcgaatc accttgaaca gtattaatat
    49741 tcatatatac acatcccctt tagtattatt atactatatt ttttaaaatt ttataattaa
    49801 ataaacagta gatataataa tagatataat cataagtgga aaacctattt tgaaatactc
    49861 cttaaaagag ataggatgac cgtgtttatt acctatacct gctagtacaa cattagcaga
    49921 tgctcctatt agtgttccat ttcctccaag acaagctcca agagatgttg cccaccatag
    49981 tggcattaca tcaatacctt cagcttgcat agtcaaaata agaggaatta gtgttgcaac
    50041 aaatggaata ttatctaaga aagaagagac tatagctgac aaccataata tcaacaacat
    50101 tgtaaataca agatgtcctt ctgtaagtcc aatcaatgct tgagccaatt tgtttattat
    50161 cccaacttct actaatccac caactactac aaataatccc ataaagaata aaattgtaga
    50221 ccattcaata cctgccataa tttcatctac atcttgtttt cctattaaaa gcattataga
    50281 tgctcctgtc agtgctacaa cagaagaatc tatgtggatt gtactgtgaa acataaaacc
    50341 aaaaagtatg aatgctatta atataaggct ttttataagt agaggtttat ctttaacaga
    50401 ttttttttca tctagtttta atattgcatt tttagctctt tcattcacaa caagttcttt
    50461 tccataaata aatctaaagc atattatagt tatagcaagt attaccataa cagcaggacc
    50521 taaatttatt acaaaatcca taaaactaag attggcagca ctaccaatca taatatttgg
    50581 agggtctcct ataagagtag ctgttcctcc tatatttgaa gctaaaatct gtgttattaa
    50641 aaatggaact ggattaagtc ctaatatttg tgtaataact atagtcattg gtccaataag
    50701 taagacggtt gtaacattat ctaatacagc tgataaaata gctgttataa tagcaaaaca
    50761 aatcattatc ttccatgggt cacctttggc tttctttgca gtccagatag ctatatattc
    50821 aaataacccc gagtttttga caacagctac aaatagcatc ataccaacta atacaccaat
    50881 agtattgaaa tctatatggc ttaatccttc atcaagtgta agtatattga atattatcat
    50941 taatagtgca ccaccaacag ctgctacgga tctgtttacc ttttctgtaa taatagctgc
    51001 cataactatt aaaaatatac atatagctat tatttgttga aattccataa tataagtacc
    51061 tccatttgta ttattttgtg cctaatgcta gtactatata tagtattact tttttattgt
    51121 tttttcaatg gatgtatgaa agtatattat ttaacaaagt ttttggaaaa ttgacagaat
    51181 ttaaagaaaa tttttgttat ttaaataaat tttaaaatta ttccattgat aataatatta
    51241 aacgacaaac gaaaaaatat accctttaaa ctagaattta ttgtatctaa taacaattat
    51301 aaaatattaa atatatctat attataaaaa caataaaaaa aggtttgatt tgaatataaa
    51361 actgcaatat attaaaaaaa ttattcattt taaaccttgt aatttgattt tataaatatt
    51421 ataattaaat taatgaattt ttaacaagga attattcatt tttttgattt taagatttat
    51481 tgagaaaaca aaactaaata ggggggtaat taatataatg gattttttca atggtatttt
    51541 aacgagtatt aacaatgcag tagtatttgt aaacaattac ttatggtcgt atatcttaat
    51601 tataatgtta gttgtaattg gtatttactt tactattaaa acaaattttg tacaattcag
    51661 atattttata gaaatgttta gacttctggg tgatggtaca gcgaataaaa atgcaaaaaa
    51721 ggaaggaaaa atctcttcat ttcaagcatt ttgtataagt acatcttcaa gagttggaac
    51781 tggaaatata gctggaatag caattgcagt ggtagcagga ggacctggtg ctgtattttg
    51841 gatgtggctt atagcattaa ttggttctgc atcaagcttt gttgagagta cattagctca
    51901 gatttacaaa gtgaaagatg gtcaagcttt tagaggtgga ccagcgtatt atatggaaca
    51961 aggtctaaat aaaaaatgga tgggtatttt attctcaata cttataacta tatgttatgg
    52021 ttttgtattt aatgcagttc aagcaaatac tgtttcactt gcatttaata atgcatttgg
    52081 aataagtaaa atggctatgg gaataggtct tggaatttta actgcaatag ttatttttgg
    52141 tggagtgcat agagttgcaa aagtttctga aataatagtt cctgtatttg caggattata
    52201 tatattagtt gctttggcta tagttgtaat gaatataaca gagataccaa gtgttatagc
    52261 attgatagtt gaaagtgcat ttgattttaa aggaatggcg attggtacat ttatgggagt
    52321 tgtaatgact ggagtgaaga gaggtctatt ttctaatgaa gcaggtatgg gtagtgctcc
    52381 taatgctgct gcaacagcac atgtaactca tcctgtaaaa caaggtttaa ttcaatcttt
    52441 aggtgttttt acagatacta taataatatg tagttgtaca gcattcatgg tattattata
    52501 ttcaggttat agtagtagtg gagcaactgg aattgaatta gctcaagaag ctttaactca
    52561 tcatatagga ccagttggaa atatatttat agcagtttgt atattcttgt ttgcatttag
    52621 ttctatagtt ggtaattact attatggtga atcaaatatg gagtttatga gtggaagtaa
    52681 gactaaactt aatgtattta gagtttttgt tgtaggtatg gttttatttg gttcacttac
    52741 tcaagtagat gtagtttgga atcttgcaga cttatttatg gcattgatgg cgataataaa
    52801 cttaatagca atagcacttt taggaaaata tgcatttatt gctttaaaag attatacaag
    52861 tcaaaaaaaa tcaggaataa aagaccctgt gtttattgca gatgaaatag aaggcctaga
    52921 aaaggtatca gagtggcata gggaattatc tgaggaacat ttaggataaa aaatagtata
    52981 aaattataaa accattttga aagactagag tatgtatata ctttatatga atataatatt
    53041 gaattaattt atattactgg aatttttaat tccagtaata tttttttaat tacaaggata
    53101 ttatgatgac ttaaagactg tggaaaactc ttttttagtt ttcattatta atattaattg
    53161 acaaatttag tttttattta aatttcttaa gtgcatataa atcgtatttt ttgataatcc
    53221 cattaagtct gcaactttaa caacagaatc cttaatttta aaaataccac tttcatttaa
    53281 aatagaaaca atagatttat ttttatcatt gctagatata ttagaatcat tttcaacaat
    53341 tacctttgca tcttggtatg attttaaaat tacttcatca gtatcttcta cgatattttc
    53401 taaaacagga gcactttgca tagcattatg ttccggaata tatgaaccaa ttattcttgt
    53461 tagtggtgta ttaagataaa aatgtatgca gagtagaccg attattttat tatcaactcc
    53521 ccttatcact atatctgttg attttaaagg ttcacctagt ttgtttctat taaaataact
    53581 gataaaatct ccatcagcat cattttcgag tttattaatg agtgccaaat caaaatcagt
    53641 tataatatct ccttctttta cagtattata tttaccatta gctattttat ttattgaata
    53701 gtgtactcca ttaaatttat ataaaataaa ctcgtatcct tctcctaaat acgcagataa
    53761 tccatccact agattgttat aagaatcgaa aatatagtta tcagtcatgt taaaagtcat
    53821 atgttacctc ctaagaaata tcttaatatc atattaacat ataaaatgaa tttaataaaa
    53881 tatatttcag tgaaataata aatataatga aaaaaaaact attgactgaa aaatatttca
    53941 gtgatattat taaaatacag taaggcaaac gtattattga cagaatatat aaaatgttaa
    54001 aaatagtatc taggaattaa acaaattaaa ggactagtga tttgaatttt tttagtataa
    54061 tatgtgactt ccaattaata tttattaaac accaataaaa ttgtaaatat gcttaatgat
    54121 atactttagc gatgaagtga aaatatttta tttttatgat taacctatag gaattaattt
    54181 agcatactgt ttagctagta aatctaaata aattttagct ttagctgata tcatgttgaa
    54241 taaagtttct attggatttt gtataacaaa ggagtgggga gatggcacaa gataaaattg
    54301 tggttgaaat tttagaaaac attggtggta aggaaaatat taaggaagta gcacattgta
    54361 tgactagact gagaataaag gtatgtgata gttctcaggt aaatcaggaa aaactaaaga
    54421 aaataaaagg tgtactaggt cttgtattaa aaggtgagca atatcaaatt gttataggtc
    54481 ctaatgtatc acaagtgtat aatactctta atgaagttat aggaattata cctgagaagg
    54541 atagtaaaaa aacaatatct gaaggtaaac aaaatagtat tgcaaaaata ttagatacta
    54601 ttgcaggtat ttttaatcct atagttccag cattagcggg tgcaggtcta ataaaagcta
    54661 tattagcatt actagtagca tcaaagtttt tatctgcaga tagtgaaacc tatataatat
    54721 taaatacaat atctgatggt gtattttcat ttttaccatt tatgttagct tactcagcag
    54781 ctaaaatatt taaaatgaat acttatgttg ctgtagcaat agcaggagca atgctacatc
    54841 ctaatttcac taatttaatt caacaaggct taactaaaat atcttttatc ggtattccga
    54901 tgtcactaat ccagtataac ggaagtgtat ttccgatagt actaactatt tggtttgcat
    54961 cgtatataga aaaaggagta gataaaataa caccaaaggc acttaagata atattagtac
    55021 ctgcattgac tattttattt gcagctccta tagcattaat tattattgga ccaatagctc
    55081 aaatgctagg aaactatata gccggtggag caagtatcct atttgaaaga ggaggaatat
    55141 ttgcagggtt aatttacgga ggaatttatt cattcatggt agtaacagga ttacatcatg
    55201 gtatggttcc tgtattagta gatggaataa caagatatgg atttaactat ataagtcctg
    55261 tgtcaggtag ttcaaatatg gctcaagcag gatctgcatt tggagtatgg ttaaaagcaa
    55321 aagataaaga tttgaaggct gtagcagcta cagctaccat atcagcatta actggagtta
    55381 ccgaacctgc aatatatggt gttaatttaa gattaaagaa accgttttta tgcgctgcta
    55441 taggtggtgc agcaggaggt ggatttgctg catatttcca atgtaaagca tttgctatgg
    55501 gaggtccatc gtttttaact cttcctatgt ttataggaga aggtggacat gtaggattgg
    55561 tagcaatagc atttacaata gcatttatag tatctgcaat agctacctat atagtaggat
    55621 ttgaagaaga ggtaacagca gattcacacg ctaacttata ataaagagaa attatttaac
    55681 atatcaaaaa ggagattaat tactatgaaa atttatttaa ctaaagatta tgaagaaatg
    55741 agccaagtgg cagcacaaat ggtgttaaag tatatgtaca gcaatgataa taaaagaata
    55801 aacctttcta taacagcagg tcaaacacca aaaagaacat acgaaatatt aagtgaattt
    55861 gttaagaata aaccttattt tgaaaatgta cattattata actttgatga aataccaata
    55921 aaaggcgaaa aagttggagt tactataaga aatttaacta atatgtactt tagagaagct
    55981 caaataccag aagaaagaat acatgtgtta gatgaaaata attatcaagg ctttgataga
    56041 aagatagaag ccgatggtgg aatagacatg gtattaatgg gattaggttg ggatggacac
    56101 ttctgtggaa atcttagtgg tacagtcaac tcttttgatg aagagacaag agctgtttca
    56161 acttatataa cagatgatat ggctaaacta ttaacaaaat ctgtaggtgg aaatccagaa
    56221 aaattatttg attactatgt gacatatgga cctaaaacaa taatgcattg taaaaatata
    56281 ataatgatag taaacggaaa acacaaagct caaatattaa agcaaacact atttggacca
    56341 ttagatttat tatgtccatc atctttattg agattacatc ctaacttcac attaatagta
    56401 gatgaagaag cagcatctga aataaaagat ttaatataaa taagtaagga attaaaatta
    56461 aaaatgaatt taggtgcaaa gtaatatttt attttgcacc tttgctttaa taaaaaggag
    56521 aataaaaatg tataatcata tgaaaaaagt attccaagga ttagagggtg ggttattttc
    56581 aagtgtagag aaagctgatg taggcgattc ttatcaaaaa ttaggtgagc agggtgtaag
    56641 tttaatggga tgggcagatc catttttccc agattactgt atacctagac atatattaga
    56701 tgcagctaca ttagcgatat caagtaatat gtcaactcat tatacagcgc ctgtaggtaa
    56761 tgacttatta aaaattgaga tagcaaaaaa attaaaagaa gtaaataatt tagatgttga
    56821 ttttaaaaga aatatattaa taactcctgg gtcagactca gggctttatt actcaatgtt
    56881 accgtttata aatgaagggg atgaggttct tataccaaca ccatgctatc caaataatat
    56941 acaaaatact aaattaatgg gaggagttcc tatatttgta gagttaaagg aatcagatgg
    57001 atatcaaata gatataacag aatttgagaa gagattaact aataagacga agttagtagt
    57061 tcttactcat cctaataatc caacaactac aatatttaat aaagaatctt tagaaaaatt
    57121 agctaaattt attatagaca atgatttaat attaatatgt gatcaagcat ttgaagattt
    57181 tacttttgaa aatgaattaa taacaccagc ttcattagaa ggtatgtttg aaagaacagt
    57241 aacaatattt tcaacatcaa aaggtatggg attaagtgga tttagagttg catatatggt
    57301 atgcagcgat aaattaatgg acaaatacta tggagcagca gtgacagtat taggtgctac
    57361 taatacagta gctcaaatgt caacgattga agcatttaaa gatagaagct ttatggagga
    57421 ttttgaaaga gtttttgata aaagaaggca agaagcatat aagataatca atgaaatacc
    57481 taatgtatct atgcagatgc ctgagtccgg atttttaggt tggataaatg tatcaaagct
    57541 tggaacatca tcagaaatac aaaagtatct agttgacgag gctaaagttt gtattaatga
    57601 tggaattaat tatggtccag gaggagaagg gcatttgaga ataattttag gaagctataa
    57661 agacgatagt aaggtaattg gtgcattaaa tagaataaaa gatgctttaa ttaaaaagca
    57721 acaataaata aaaaataatt ggagtggagt atgttatcaa tatttaagag taaaaaaaat
    57781 gacaacaagc ttaaggcatt tgcatcaggg aaagtaattc ctatagaaga tgttgatgat
    57841 aatgtttttt catctaaaat gttaggtgat ggaatcgcta tttatccaac taatgaatat
    57901 gttgtagccc cttgtgatgc agaagtaaat ataataatga aagatactaa acatgcagtt
    57961 ggaattaaat tatttaatgg catggaaatc ttatttcatg ttggaataga tactgtatct
    58021 atgaatggag aaggttttga gatatttgtt tcaccaggtg acaagataaa aagaggtgat
    58081 aaattaatat cttttaatag taaattaata aaagaagaag ggttacaaga tgtagttata
    58141 atggtagtta ctaattcaga acagtataaa aatataaaat atcatattgg actggaggca
    58201 gtaatcgatg atactattat tgcagaaatt taaaaacagt tatttaagta aatacttaga
    58261 taatttagat atagttaaaa ttaaatcctt aaaatcaaat tatttagttt ttgtgtaatt
    58321 ttaactataa agccgattaa taatataaag tatactaaat aatatggtta ttatgattgt
    58381 tactgacaaa gcctaagtag atataacaat ttgctctaat tgagtattgc tatatctact
    58441 tgtttttata tttaaaataa aagagtctgc attgaaaaga taattctgat gagagtaaat
    58501 agggtattta ataatagttt aattctgact tatcaagatg aacctattca tatacctaaa
    58561 acatctttaa caccttctaa attcatacaa atagctgtat aggctgcctt attgattatt
    58621 tttccgtcaa tttttacttt gtagtgaaca gcatatataa atattatcga atagattgta
    58681 tcaagagctc tattttgcta ttcattagct aaagatagta ctctgtcagt tatttttgaa
    58741 actaatgcat gagatatatc aattccgtaa atattattta aatgtatgat atatatcgcg
    58801 agtcgacatt ccttttgagt acatgccaat tacttggttc tctattccag aaatttcatt
    58861 ttcgtaattt tgaataaccc taggctggaa atcatcccta gggatattta attttacctc
    58921 tccaaaatct gatttaacat tcttagctct atatccattt cttgaatttg atgttgcttt
    58981 actttggtta tcatatctct cgtacattaa atgatcttca atctctggct ctaacatttt
    59041 gtgaattgtg cttgcgaata aatcttttaa catctcttgg atgtctttag tattttttac
    59101 atcatactct tgaactaagt gttttaatat ttaatttttg ttgtacataa aaaatgtgta
    59161 cctcctattt tggtaattag atttaatatc ttgactttta ggagaataca cattttattt
    59221 tacagaccct cttttctaga aaagttttta tgaaaattgt gatataaatt attaataaaa
    59281 aataatttta tatttatttt attatgtaat ttagttttat taaaaatttt ttattattgg
    59341 atatagatta tctattataa attttatctt taagtttatt ctcctaaaat actatataat
    59401 taaatcctgt aaattatctt caaagctttc taggtaatca caaaataatc taaattcttc
    59461 tatggtttta atttcttgta aatttctcaa atctatcatt atattactat atttatgaaa
    59521 cataaaattc atatcataca tttcacattt aacaaattca ttttgataac tatatttata
    59581 aggttcgtat tttgaaaaac tcgactcaaa atattttatt ttagcataac ataatttgtg
    59641 tatgttgcac aaaagtgcaa gaacagactc cttaactgca aacttatgtg taaagtattt
    59701 tatcgtgtgg tatttaccat gtttaaactc ccaaattaaa tcctcattta aagtaagaga
    59761 atattttttt ataaggttac gcgtatctag tgttaaattt tgtattgaat gtattttcat
    59821 aatttattct cctcataaat atttaataag tattaaatta tagtgtttta ttattaattg
    59881 ttcttaatta tattgtatgg taaattaaaa aagtaataaa atagataatt aatatactag
    59941 taatatatgc tataaataaa aacaatagct aaaatagtaa tatatatgtt tttataatat
    60001 tttatgttta gggttatatt tgtaattatt ttaagcttct aaaagtagat ttgatggata
    60061 acgtataatt ttagaaggat atgcaatttg tttgataaga acgtacatat gattaaatta
    60121 aaaatattaa gtaccaaaaa gaagaaagat agtttctccc tttggtactt aatattttgt
    60181 atcctttaca ctaattttta atatttatta atgatattat ttaatctaga gacttaaata
    60241 aatttgccat ttctagcgca ttcatagcac aatcataacc tttatttcca gcttttgtac
    60301 ctgctctttc aatagcttgt tcaatatttt ctgtagttac gattccaaat ataacaggta
    60361 attcactgtc taaagatact ttggctatcc ctttagagac ttcactacat acataatcat
    60421 aatgagaagt agcccctctt ataacacagc ctaaacagat tatagcatca tacttaccac
    60481 ttttagccat tttttgagca acaagaggaa tctcaaaagc tccaggtacc caaactattt
    60541 ctatattttc tggagaaacg tcatgtctta aaagacagtc ttcagctcct gataaaagtt
    60601 ttgatgttat aaattcatta aaacgagaat ttattatacc tatttttaaa tcttttccaa
    60661 taagttttcc ttcatatatc atttttattt cctccaattt tatttatgtt atagatttat
    60721 atttataaat atctttaatt taattataaa aaactactta gtagaaaaat atcatcatat
    60781 aatcatttat ataatatcta aaagatgtcc cattttatct tttttagttt ttaaatatag
    60841 cttattaaag tcattaattt cttcattaat agggattcta ttttcgattt ttattccata
    60901 tttctctaat tgatttattt tatctgggtt attacttaaa agatttatac tttttatgtt
    60961 taaatttttt aatatttgag cagccatata gaaatctctc atatcttctt caaatccaag
    61021 cattaaattt gcttcaacag tatcgtaacc ttcttcttga agtttataag ccttaatttt
    61081 atttaaaaga ccaatacctc taccttcttg cttcatataa attaaaactc cacttccatt
    61141 ttccacaatt ttcttcatag aagattctag ctgtaatcca caatcacatt ttagagagtg
    61201 gaacacatct cctgttaaac attcagaatg aagtctaact agagtatttt ctatatttat
    61261 atttccataa gtaagggcaa tgtgttcttc atttgaataa gtatctctat atcctatgat
    61321 ttcaaaattt ccatattttg tcggaaggaa agcactagat actttttcta tagtagtttc
    61381 atttattttg cggtattcta taaggtcttt tatagtgatg atttttaaat tatgcttttc
    61441 tttgaaaatc attaaatcat caactcttgc cattgtacca tcatctttca ttatttcaca
    61501 gataagacca atctctttaa aacctgcaag tctagcaagg tctactgagg cttctgtatg
    61561 tccatccctg acaagaaccc caccagtttt tgctattaaa ggaaagatgt gaccaggcgt
    61621 tttgaaatct ttacttgtag aattttcatc acagaacaat tttacagttt cagctctttc
    61681 atatgcagat ataccagtta gagtatctgc tccatctata gtaacagtaa aggctgtttg
    61741 aaatgtatct gtattttctc taaccataag aggtatatta agacttttaa attttttttc
    61801 agtggcaggt agacaaatta gacctctacc atatgtagcc ataaaattta ttgattcagg
    61861 agtagccatt tcagctgcca tcaataaatc tccttcattc tctctacttt catcatcaac
    61921 tacgattacc attttcccat tttttatatc ttcaatagct tcttcaatag tattaaacat
    61981 gtaattcact cctttattat ttttaaaaac catttttaaa taaaaaatct ttatctatat
    62041 ttgatttatg gttactacta ttagaattta attccttgta gttattagcc ataaaattat
    62101 taacatactt tccaattaca tcgctttcta aattaacgaa atctccaaca ttctttgtca
    62161 agagaatagt gttaatttta gtatgaggta taatagaaac cttaaatatt tcatcatcta
    62221 aatatgatat agttaaactt acaccatcaa tagcaacaga acctttgagt atcattgagg
    62281 ataaaagttt tttatcaggt cgtatactta ctaaaactgc attttcatct ttttcaaatt
    62341 tgcagatagt tcctttacca tcaacatgac ctgttactat atgaccacca aatcttgaag
    62401 aaagactcat agctctttca agatttacct tgtcatttgc atttaataaa cctaaatttg
    62461 tggaacgaat tgtctccatc ataacatcgg ctgtaaattc attttttccg aggtttgaaa
    62521 cagttagaca aactccattt acggctatac tatctccaag atttgtgcca tctaatattt
    62581 tatttgatag tatggttact tttccactct taccattagc agtaattttt ctaagtattc
    62641 caacttcttc tactatgcca gtaaacatcc taacctccta tatgaatgta ttaacaaaaa
    62701 tttaatttaa aacatctgat tctataagaa tatcgccatc tatcaaagtt acattattga
    62761 ttgttaactg tgttgaatct gacaaatgat ttattccttc tccagaaacg aatgtaggtg
    62821 catctttacc acctataatc ttgggcgata gaaataattt gactttatca actaacttat
    62881 ttctaaagag actgtcattg agagtagcac caccttcaac tagaacagaa tcaatgttta
    62941 actctcctaa tttatacatt acaaactcca aatctactaa gttgtttttt gaaggagaaa
    63001 ttattgtttc aacattattt tcttttaaca tagataattt tatactttct ttgcaacatg
    63061 tgaaaactat agttttactg gttttatctt taaccaaatt actattaagt ggcaacttta
    63121 ggtgtgtatc tattactatt cttgtaggat gagacacttt ttcttgattg agcctacaag
    63181 ttagtaaagg attatcgttc aaaactgtat ttatgccaac cattatactt tggtatttat
    63241 ttctgtattt atgagttaga taccttgatg attcattaga tatccatttt gattctagtg
    63301 attttgtggc aattttacca tctagactta ctgctgattt tacaatacaa agaggtcttt
    63361 tgttttttat atgataaaaa aatgcctcat ttaaatctct tgcttcatct tctaatattc
    63421 ccacagtaac atcaatattg ttatctttta atttttttac tccattacca caaacaagtg
    63481 gatttgggtc taatgtagat attacaactc tcttaatctt attttgtata attttatcta
    63541 cacaaggagg cgttttccca taatgagaac atggttctaa gtttacataa agagtagagt
    63601 cttttagact ttgtttagca ctgtttatag catttacttc agcatgatta gagccaaatt
    63661 tctcatgata tcctttgcct attatattac tatctttaac aattacacat ccaactaatg
    63721 gatttggatt tacaaagcct tctccatttt tagccaattc aatagctttt ttcatataat
    63781 aaatatcttt ttctttttga ttcacaaaat tcacaatatg tacacctcct gtttaattgg
    63841 ataattttta aacaaaaaac cctgagaatt aactcagggt ttagaataat ctacaataaa
    63901 tgtttaataa atgtagaaca aaattgctct acaaaaacac tcattaaata tcttcttcca
    63961 tccagacttt actgtcggct ttggaattta accaaatcaa ccaagtttta cattggctcg
    64021 cgggctatac cgccgattgg gaatttcacc ctaccccgaa gattaagtat taaatttata
    64081 tttagaatgt atcataaatt attttacttt gcaaactatt tttttaaaaa atatatgtta
    64141 atatataata tagaatgtct ataaactttg aaataccacg attgtgaata taaaaataaa
    64201 aatttgaaca taatcaggaa agaagtctaa ttaatttaaa ttaggagagt aatatatgaa
    64261 taaaaaactt ttagaaatac tatcaaaata ctatggatat acaagtttta gaaaaggtca
    64321 ggaatctata ataaattcta tcttaagcga aaaagatgtg ctagctatta tgccaacagg
    64381 agggggaaaa tcaatatgtt atcaaattcc agctttgatt ttagatggaa tgacaatagt
    64441 aatttctcca cttatatcac ttatgaaaga ccaagtagat gccttaaaga ctatgggaat
    64501 tagtgctgct tttataaata gttcattaag cagcaaagaa tttaatgaaa tattaaataa
    64561 tattagaaaa aataattata aaatactcta tattgctcca gagagattag atgcacaaga
    64621 gtttattgag ctaataaata ataacaatgt aagtcaagtt gcgatagatg aagcacattg
    64681 tgtatctcaa tgggggcatg attttaggtt gagttataga aggatttctg attttataaa
    64741 aaatttgcct aaaagaccta tagttacagc atttactgca acagcttcag aagaggtaag
    64801 aactgatata ataaatttac tgtgtttaga aaatccagat tattatataa ctggatttga
    64861 tagagagaat ttatcaataa atatagtaaa atcatctagt aaaaataagt atattttaga
    64921 ttatattcaa aatcataaaa atgagtctgg aattatatat gttgcaacta gaaaggaagt
    64981 tgaaaatata tataatggtt tatctaagag aaatatatct gtgtcaaaat atcatgcagg
    65041 tttatctaaa aatgaaagaa gtaaaaatca agaagatttt ataaatgata atgtggatat
    65101 aatggtagca acaaatgcat ttggaatggg tattgataaa cctaatataa gatgggttat
    65161 acattacaat atgcctcaaa gtatagaaaa ctactatcaa gaaataggta gagctggtag
    65221 ggatggagaa aaaagtgagt gtgtactttt attttctcca ggagatgtac atatacaaaa
    65281 atatttaatt gatattggag ttgaaaatcc tgaaagaaaa ttatttcagc ataagaagct
    65341 tcaatacatg attgacttag tttacagtaa ttcatgctat agaaagacaa tattgagtta
    65401 ttttggagaa aattatatag acaattgcaa taattgtagc aattgtttag tagagggtga
    65461 aatagtagat aaaactatag atgcacaaaa agtcatttca tgtgtagcta gaatgaaaag
    65521 aagttatggt gttactacta ttgtagatgt gcttagaggt tctaagaata aaaagatttt
    65581 acagcttgga ttaaatactt tgtctacata taacattatg agagattatt ctagtgaaga
    65641 cttaaagaat tttataaata cattggtttc tcatggtttt ttagatttag ttgagactct
    65701 aggcaatgga aatagaggta gttttcctac tataagatta aatgagatgt ctatgaaagt
    65761 tttaaaaggt gaagtgaaag tagagtttaa agaaattgtt atgacaaaat cattggaagt
    65821 agaggatgag ttatataatg ctttaagaga acttagacat tcaattgcaa gtgaagaaag
    65881 gatagctcca tatatggtat ttggagatgg tacacttaga gccatgtcta gtagttatcc
    65941 aattaataaa gaagaaatgc tagatatctc tggagtagga gaaattaaat accaaaaata
    66001 tggtagagat tttgaagcag taattaaaga atatgtcgaa aaaaataata taaataaaaa
    66061 aatagatgaa aaaaatgtcg attcaaagaa cgttaatagt gatttcttag aggttaatac
    66121 agataaagtt ttatatgaaa aactgttagt cattagagaa gaatatgcaa caaaggaaaa
    66181 attacctgca tatatgattt tagccaataa ggctttgaaa gaaataagtg gaagatatcc
    66241 acttgatgaa gaacaattaa aagatatttc tggcataggt ggagtaaaat ttgaaaaata
    66301 tggagctagt attttggcag aggttaataa atatgtaaaa gaaaataata ttaatgttat
    66361 ttgggagaaa aagggcaaaa ggaagttaat attagatgga gaaagtagaa aaaataatga
    66421 aatagcatta gatttgctaa atcaaggaaa agatatacaa agtatcagtc aagaaataga
    66481 agtttcactg tcaaccatta ttggatatgt gcatgactat gtaaaggatg gacatagtat
    66541 atcatttgaa ttaggactag aaaattttta taatgaagat aaaaagaaga tgattttaga
    66601 agtttgtgaa aaagttggct atgataattt aaataacata aaaagaaaac ttccagattc
    66661 aataaagtat gaaaatataa gagctgtgat acttgactct tatcttgaaa acttaaaaaa
    66721 taatattata gcagagtaat ttttaactta ataaaaaata aaatttgtat tattgtgttg
    66781 aactaataat tttgctgtgt tatactgaat ttgtaaaaat aatgaaaaat tagagctagg
    66841 ggcgctagaa ttggctagct gagagataaa gccgtaactt acaaacccta ataacctgat
    66901 caagataatg cttgcgaagg gaagcttttt aatataattt tattatataa ataggcaaat
    66961 tattcaatgt taggagaaat ttgtctaagt gtatatacga ttataagagt gctttccaaa
    67021 cgaggaaaag cacttttttt attttcaaaa actataactt taatcttgga ggattgtaat
    67081 atgaactata caacacaaat ggatgctgct agaaaaggca taataactaa agaaatggaa
    67141 atcgtttctc aaaaagaaca ggtagatgta aatgaattaa gagaattaat agcaaatgga
    67201 caagttgtta taccagctaa taaaaatcat aaatctttaa gtgcagaagg tgtaggtaaa
    67261 aatttaagaa caaaaataaa tgtaaatcta ggaatttcaa gagattgtaa ggatatagaa
    67321 aaagaacttg aaaaagttag agtagcaata gacatgaaag ctgaagctat aatggattta
    67381 agtaattatg gcaaaactag agaatttaga gaaaaggttg ttgaaatgtc acctgcaatg
    67441 ataggttcag tacctatgta tgatgcagta ggatatttgg aaaaagaatt aaaagatata
    67501 acagaagaag agtttttaaa tgtaataaga caacatgcta ttgatggagt agactttatt
    67561 actatacatg caggtcttac aagaagtgtt tgccaaaaaa taaaaaatca tgagagattg
    67621 actcatatag tatctcgtgg aggttcttta ttgtttgcat ggatggaatt aaataataag
    67681 gaaaatccta tttatactaa ttttgataaa atattggata tatgtgaaga atatgatgtt
    67741 acattgagtt taggagatgc ttgtagacca ggttgtataa aggattctac tgatggtgtt
    67801 caaattcaag aacttgtagt attaggtgaa cttactaaaa gagcatggga aagaaatgta
    67861 caagtaatga tagaaggtcc tggacacatg gctattgatg aaatagaagc aaatgtagta
    67921 ttagaaaaga gattatgcca tggagcacct ttttatgttc ttggaccatt ggttacagat
    67981 atagcaccag gttatgacca tataacaagt gcaataggag gagctttagc atgtgccaaa
    68041 ggagtagatt ttttatgtta tgtaactcca gcagaacatt taagattgcc taatttagat
    68101 gatatgaaag agggtataat agctgcaaag atagctgctc atgcaggaga tatagctaaa
    68161 aatgttaaag gtgctcgtga atgggataat aagatgagta aagctagagc tgatttagac
    68221 tggtgtgaga tgtttagact tgcaatagac cctgaaaaag ctaagagata cagagatgaa
    68281 tcaactccta ctcatgagga tagttgtact atgtgtggaa aaatgtgctc aatgagaaca
    68341 gttaagaaaa tattaaacaa tgaggaactt aatctaatat aatttttggc tagtatgact
    68401 ggaataaaaa gaagctgaaa agaggaggtg atttagtgaa ggttaatggg aaggaaattg
    68461 aatttgaaaa agatttgact gttatagatt tattaaataa atataattta aaaagtgata
    68521 gagttgtagt tgaagtgaat ttagagataa ttgaagaatc taactacaat acatatgtat
    68581 taaaagacga ggacattgta gagcttatta gctttattgg aggtggttaa aataaaaata
    68641 tttgtaaatg aattattaac agatgttgag gaaaatacaa ctgcttataa agttagagat
    68701 agctataaca ataaatgtga tgtattggtg ttaaatggat atccaattaa aacagatatg
    68761 cccctttttg aaaatgataa attaacactt atacaaaaag gagttaagcc atcacttgat
    68821 gaattagaaa gcttgttgat tgctagacat actccaaata tacataataa attaaaaaaa
    68881 gggaaagttg ctatattggg attgggggga cttggttcca atatagctat ctctttagct
    68941 agaataggag tgggagaact tttacttata gattatgatg ttgtagaacc atctaattta
    69001 aatagacagc agtattttat agatgatata ggaaaactaa aaactgatgc catgatagaa
    69061 aatataaaaa aaataaatcc atttataaaa ttaaataaac gagatatttt tttaaacaag
    69121 aacaatatgg atactattaa ggattcagat ttaataattg aggcctttga tgatgcttca
    69181 tgtaaagcac aggtatgtaa ttatgtatta ataaatttaa aagataaata tttaatagca
    69241 tcatctggta tggcaggtta ctatgattca aatataataa ctactaagaa gataaaagac
    69301 aggttttata tatgtgggga ttttgtgaat gaagctaaat ttggtaaagg gcttatggct
    69361 ccaagggttg ccatctgcgc aaatcatatg gcaaatttgg caacgcaaat acttatagat
    69421 atgtaaatat taaaattaga tataaaaaag attgaatatt aaaaaaattt aacgtggagg
    69481 gaaataatat ggataaattg atacttggtg gacatgaatt taatagcaga ttattggttg
    69541 gaacaggtaa atatggttca aataatatat tgcctgaggt aataaaagaa agtggaagtg
    69601 aaataataac aatggcactt agaagagtgg atttagacaa taaacaagaa aacatattaa
    69661 cgtatattcc aaaagagatg acaatacttc caaatacatc aggagctact aatgcagaag
    69721 aagctgtaag aatagctaga atatctagaa aaatgggatg tggagatttt ataaaaatag
    69781 aagtaatatc agatactaga tatttacttc ctgataatga agaaactata aaagctacaa
    69841 agatacttgc tgatgagggg tttatagttc ttccatatat gacaccagac ctttatgctg
    69901 gaagaagact tatagaagct aatgcagcgg cagttatgcc acttggagct ccaattggtt
    69961 caaatagagg tcttcaaatg aaagaaatga taagaataat gatagatgag ttggatatac
    70021 caataatagt agatgcaggt attggaaaac catctcaagc tatggaggct atggaaatgg
    70081 gagctgatgc agtacttgtc aacactgcta tagcttcagc aggagaccct gtacaaatgg
    70141 ctagagcatt taaattagct gtagaaggtg gaagagaggc atatattgca aaaacaggaa
    70201 atgtgtcaga atttgcaaat gcatcttctc ctttaacagg ttttttaggc aatttataga
    70261 aagtggtgat tggtgatgag tttttatgat gtaatagaaa aatataggga ttttgatttt
    70321 gatggatatt taaataatgt tactgataat gatgttttaa gaagtttatc aaaagacaag
    70381 cttgaagatt ttgatatatt aaatttgctt tctaaaactg cagtaaaaca tttagaagat
    70441 atggcacaaa aagcacataa attaagtgtt caatactttg gtaaaacagt atgtttatat
    70501 acaccaatgt atatagcaaa ttattgtgtt aatcaatgtg tttattgtag ctataatata
    70561 aagagtggaa taaaaagaaa aaaattaact atggatgaaa ttagagaaga gggagaagca
    70621 atttcaaaag aaggtttcaa acatctactt gttttgactg gagaaagtag ttttcactca
    70681 agtgtagaat atataggtga ggctatagaa atattaagag agaaatttcc ctctataggt
    70741 atagaagttt atccaatgga agtagaagaa tataagtaca ttgtagataa aggtgttgaa
    70801 ggattaacag tatatcaaga aacttatgac gaggaaatat ataagagagt acatataaaa
    70861 ggcccaaaat caaattataa atttagacta gatgctcctg aaagaggggc aaaagcaggt
    70921 atgaggactt tatcaatagg tgcactttta gggctaaatg attttagaaa agaaactttt
    70981 tttacaatat tgcatgggaa atacttaaaa acgaaatatc ctcatattga gctttcatat
    71041 tcaacaccaa gaatgagacc ttttaaaggg tgttttgagg aattggtaga tataagtgat
    71101 actgatttag ttcaagctat ggtatgtatg agattatttg accctcatgc agctataaac
    71161 atatccacta gagaaaattt agaaatgaga agtcatataa tacctttagg agtaactaaa
    71221 ttgagtgcag gtgtatctac tgatgtagga ggtcattctc aagatgaaca tgatactgct
    71281 caatttaaga taaatgatga aagtactgtt aaagatgtgg agaaaatgct aaactcaatt
    71341 ggttatcagc atgtgtttaa agattgggaa agattttaaa tgtatctgat aacaaacaga
    71401 aaattatgta gtgaggaacg atatttagaa gttattaaag agtctatatt gagtggtgta
    71461 gaaaatataa taataagaga aaaggatttg gaatatcaag agctaagaaa attatatatg
    71521 aaaataaaaa ctaaaatcaa ttgtatagat tttcaagagc aaatatcaga tgaaagtttg
    71581 aaaactaata taaatcaaaa agagtgtaga aataaattca aggttaattt tataataaat
    71641 agtaacattg aattttttga aaaagtggat tgtcaaggta tccatcttcc ttttaaattg
    71701 ttcttgaatt taattgaaaa taagtataat tttaatgaaa ataaaatact aggattatct
    71761 ttacataaag tagaggaagt agattattta gaaaaattaa taagaaatca aaatataaaa
    71821 atagattaca taacattatc acatatatat gaaactaaat gtaaagaagg attaaatcca
    71881 aaaggaattg agcttttaaa agaagctaaa aagattactg atattaaaat aattgcactt
    71941 gggggaattt taccatctaa tgtcaaggaa acattaaaat actgtgatga ttttgctata
    72001 atgtcaacta taatgaggtc taaagatatt aaaaaaacca tatcaaatta taatgaaaag
    72061 ttgaattagt aaatatagta tattgaattt ttaacttaaa taaaaataaa aaagttatct
    72121 tttaaatttt aaaaggtagc ttttttattt tatatctttg ctaataaaaa attgtaaaaa
    72181 gggaaaactt tagtcagaga gattaaacaa tatcctagaa agatttaaaa tttagtaaag
    72241 tatggaggac attataatga ctgacagtaa aaagaaacga tttattatac cacacacttt
    72301 tacaataata tttttactaa tagtcttaat ggcaatattg acttggatag taccaagtgg
    72361 tgaatttagt agagaagatg tagaaggtag aatggtagtt gtaccaggga cttatcaaag
    72421 tgtagaaagt aatcctcaag gatttgcaga tgtttttaaa gcaccaatag aaggctttat
    72481 cgattcagct gaagttgtag gttttgtttt aatagttgga ggtgcttttg gtattgtaaa
    72541 taggactgga gctatagaag caggaatagc ttcggttatc tctaagttta agggaaaaga
    72601 acttcttata attccaatat caatgatttt atttggactt ggaggtacaa catttgggat
    72661 ggcagaagag acattaccat tttatatgat atttgttcca ctcatgacat ccttgggata
    72721 tgattctcta acagcaatag caattgtatt tataggagca gcagcaggag cagccgcttc
    72781 aacaataaat ccattttcag ttggtattgc acaggcacta gctcaacttg ctcctggttc
    72841 aggagtaact tacagagtag ttatttttat agcatatata ctaataagta tagcatttgt
    72901 tatgtactat gctaagaagg taaaggaaaa tcctgaaagt tcaatagtat atgaaataga
    72961 taaaaataat aaatcaatac ttaatcaaac ttcaacagaa ataaaagaat ttacttttaa
    73021 agaagtgtct gttcttgcta tatttggaat agggatggca ataatgattt ggggtgtttt
    73081 aagtcaagga tggtacattc cagaaatatc aatgtgtttt gctgcaatag gtgtgctttc
    73141 tggattggtt ggtagattat ctcaaattga aatctcagaa agttttatag atggagcaaa
    73201 agatttagca tctgcagctc ttgctatagc tttggctcgt ggaatcgtaa taattgctca
    73261 aaatggattt ataatagata ctatattaaa ttccgcagca gcctttctag gtgggcttcc
    73321 aaaggttata tttgtatatt tatcattttt cttggaagct gcattggcat ttttaattcc
    73381 atcatcttca ggtcttgctt cacttacagt acctgtactt gctcctcttg gtgatttggt
    73441 taatatatcg gctcaagtga tagtaaccgc ttatcaattt ggtgtgggtc ttacaaactt
    73501 tataactcca acttcaggag tactgatggg agcacttgca gtagcccata ttccattttc
    73561 aaaatgggta agatttataa tgcctatctt gttgattttg acagctgtat ctctagtctt
    73621 tttaacaata ggtatttata tagggtttta attaagtgta gttttattta agatatttag
    73681 taatggtata aaatgataat atgttttcaa taaattgcca ctaatttaat tagtggtaat
    73741 ttgttttttg tatttaaaaa taaatgtatt tacttgtatt ttgaattaat atctacttag
    73801 acattgtttt aattgttata tttttattta attaagcatt gatttatcat tttttatatt
    73861 tcatataaca atgcaaaaaa taatttttat atagtaaatg acaaaagttt acaataaatg
    73921 tatattttct tactcattcc ttaaaattac tcatttagtt taataactct catttcatat
    73981 gtaaagttgg taaaaaaatt aaaattaaaa gtaaaaaact aaataaatta atgttaattt
    74041 gaaatatata tgaaggtttt tggagaatac ttacttatga taggaaaaaa tgttaaaata
    74101 atagtgtaat caaatataaa ggactgaaat aattaacagt tattaaatat taggagtgta
    74161 aaaatttatg ggattaaaag aatttgattt tattgaagag tctattgata tgttgaggac
    74221 aatgtcacca acattagaaa ctatatcaga tgaaatagaa gagtattttg aaaatatctt
    74281 ggatgaaaag aatcaagaat atataaatgt aacctctaga ataaaatcag aatcaagttt
    74341 aagagaaaag ataattagaa atagatattt aaaaaaatat ggagaagcaa gtaatcttat
    74401 tcataatgtt tctgacttaa taggcctaag aattgagtgt agatttattg aggatgaaaa
    74461 caaaatatat agacttttga gaagatattt taataaaaca gatgacaaaa taaactatta
    74521 taataaagag aataagaata ttaaattaaa actatctgag agacaaccca ataagcaaaa
    74581 aaatggattt gaaatatata aaatagatgg agtttttgcg tatttagata gagaagtaaa
    74641 atttgaactt caaattaaat ctcttgtaaa tgtgttttgg agtgaaatag aacataaaat
    74701 aatttataaa aacaatacat atttacttgc tgataaattt ataaaggata tgatggactc
    74761 tataaagaat aatcttacta tgatagataa tcagctttta agtatttata aaaactttca
    74821 ttcagggaag tcttttaata tgaaagtaag taaaaaagaa attgaaaaat tatttgcgaa
    74881 attagtctat gacgcttttt ctgaaaagat gaataaaagt ataggttttg ttgtagattt
    74941 taaaaaacca tgtgagacta tattgaacta ttcttttaat aagcaagata taagtgatga
    75001 agttttaggt aattttatgc ttgatgagtt tgcaagatta aatgaaattg taaacaagga
    75061 tatagatttt aatgagcaaa tagaatttga aagagaacca acatttgatg ataagttttg
    75121 taaagaccta ggaaatcatt ttagaagtag attaaacaca gaatttccat ggaacctatt
    75181 ttttagaata ttatttgaaa tagagccata taacaatacc aaagactttg aaaactttgt
    75241 agagtttata aaagaaaatg tgctactaga agaaaatagg gagcaattat tatgccaatt
    75301 tgaagaagat agcaagctta taattgaaga tatatatgat tgtatattta atagtataag
    75361 tgagattgat agtgttgaaa ttttatataa ctataatctt gaaaaaataa actttacatc
    75421 aagtgaaatc ataaattgta tatgtagaga atatgagtgt tatggtgaat acttagaaga
    75481 aaaagaaaag cttatgaata catttaaaga aaagattatt caaatctttg agtaataggt
    75541 caatgctgaa gtggcgctaa tgcgccattt ttcaaatata tatgaattaa gtaaaattat
    75601 tttggaggag gcgatttgta tagagaaaac aggtgtaatt ttggcagggg gaagaaattc
    75661 tagaatgggt agagataaag cctttttaga gttacatgat aagcttttta ttgaaattgc
    75721 aatagaagca tttaaaaact ttgatgagtt gataataata tctaataatg aagaattata
    75781 ttctaaatac gatattaaag tttataatga tatagtaaaa gatgttggtc caattggagg
    75841 aatatatact gctcttgaat atgcaaagta tgatatagtt acaattgcat gtgatatgcc
    75901 atatctaaat aatcaaatag tcgaaagaat agctaataaa atggatgata aaagtgtgat
    75961 ttcagtgaca aatggaaagt tacaaccatt gtgttctgga tataaaaaga gtataataaa
    76021 taaagtatct ttatgtataa gggaaaatga tttaaagctc agaagcttta tagataaaat
    76081 agataaaagt tatatatact ttgatgaaga agatttattt ttaaatgtaa acactgttga
    76141 tgagtataaa aaattaacta aagtttaatt agctatggtt gtaaaataga gtaggattta
    76201 tatggaggag agtttatgaa tttacttaaa tgcgattctt gggcagtaat attaaataat
    76261 agcgataaag aaagtaaagc atataaaata ttagatgaac ttaaaaggaa tatgtacaaa
    76321 gttgttgcta tagatgaaga gaaaaaacct attgaaggaa tagatgtgta tgaatgttta
    76381 aaagatgttc cacacaatat tgatgttgta gctattattg ataaacaatc taagatggat
    76441 gtgattttag aagaagtaga gcttttggat atacaaaata tgtggtttga aaaaggaagc
    76501 tttagtgaaa tgatgattaa aaagactaaa gatttaaaat taaatataga atataattta
    76561 agtttatatg atgagttgac tagataaaat tatatttctt aataataaaa atataattag
    76621 ttaataaaac atattatttt atagtataga ttggttaata aaagtacaga ttggttaatg
    76681 aaacattaaa ttacaatatt tgttaaaaaa attgtgagtt acatgatata atgtattaaa
    76741 taggatacta aggagttgat atattatgtt aatagtaact acagaaaaag tagaaggtaa
    76801 aaagatatca aaggttttag gattagtgag aggaagtaca ataagagcaa aacatgttgg
    76861 aaaagatata ggagcaagtt ttaagaatct tgttggagga gaacttactg gatataatga
    76921 aatgctcact gaagcaagac aaattgccat aggtagaatg gttgaagatg cagaagctaa
    76981 aggtgcaaac gcagtaatag catttagact gtcttcagct tcagttatgc aaggggcagc
    77041 agaaatgctt gcttatggaa cagcagttgt tttagaagat gataatagta ttcttgaaaa
    77101 ataaaatata aatagttaaa aagaggcatc ttttaaaaat tttatggatg ccttttttta
    77161 tttgaaaaaa ctaatttgag aagaaatttt aactattatg acaataaaat tagggtgata
    77221 ttatataaat aagtaaaatt atattatata atgtatggta tagactttaa aaattttatt
    77281 tgtagagaaa aatatggaca atgttataat aattatagaa attaaaagta cttacattca
    77341 ttatgtatgt gacatgtata attagtttta tatttaatac agttttgaag taatatcttc
    77401 attttgagaa cgttggaata ataaaaaatg tattattata ggtgatataa ataaaaaata
    77461 aatataatat gttatattgc tgatagaaaa gagaataaaa gaaaataggt tttattaaaa
    77521 gagattttta tttataggac ttaatcaatg tatagagggg tgagaacata tgtttaatgt
    77581 tgcaattata acacttagtg ataaaggata tgaaggaaaa agagaagata taacaggaaa
    77641 aaagttaact gaatttgttg aaaatacagg agcttataaa gttactgaat atgtacttat
    77701 aaaagatgat aaggaaatgc taaaggaaaa tattataaga ctttgtaata gtaataaaat
    77761 agatttaatt cttacaaatg gaggtactgg tttttcaaaa agagatataa ccccagaagc
    77821 aactaaggaa gtgttggaaa aagaaatacc aggtctgagc gaatatatga gaatgaaatc
    77881 cacagaaatt actaaaaagg ccatactaag taggggtgta agtggaataa gaaataattc
    77941 tataataata aatttacctg gaagtcctaa aggtgcagtt gaaaatctaa gttttataat
    78001 tgatgtttta gaccatggca tagaagtttt aagaggagaa gctacagaat gtgccactaa
    78061 aaaaagtgaa tagtatataa tctagataga taaaaaatag acaaagaggt agataaagta
    78121 tgattgataa gtatggaaga aaaatagact accttcgtat ttcacttaca gataagtgta
    78181 atttaaggtg tgtttattgt atgccaccag atgtaaaatt tgataaaaat tatataaatg
    78241 aaaatctaag ctttgaagac tacaagttta ttataaaggc tatggctgaa caaggtataa
    78301 caaaaattag atttactgga ggagaacctc ttttatatcc taaattaaat gagcttataa
    78361 aatttacaaa agaagaatgt ggaataaata acataggaat gaccactaat gctattgggc
    78421 tttctgatag aatctttgag cttgaaaaat gtggcttaaa taaagttaat ataagtttag
    78481 attctttgaa ggaatataag tataaatccg taacaagagg aggaaactta aaagatgtct
    78541 taaaatcgat tgaatcttgt ttaaacttag gtataaaagt aaagttaaat tgcgttgcta
    78601 taagtgggtt taatgatgat gagcttaaag attttatgtt tttaacagtt aaatcaccaa
    78661 ttgatgtaag atttatagag cttatgccat taggtgaggc taatagagtt tataagaagg
    78721 gttattttaa tgtaaaagaa atgattgaaa aaatatatgg tttatataaa gtcaaaaatg
    78781 atgaaaaaag tacagcagaa tattatatgt ttaaaggagc taaaggaaga ataggaatta
    78841 taactccatt aagctgttca ttttgtaaca cttgtaatcg tattagactt acttctagtg
    78901 gtgcaataaa attatgtcta cattcaaaag aagaaataga tataaaacca tttttacata
    78961 aaccattgtt atttagagaa tctatgaaag atataataaa acaaaaacca gaaaaacatc
    79021 atttactaga aaataaatgt agtgatacaa ataggcgtat gtatgaaatt ggaggataag
    79081 taatgttaac acatataaat gaaaaagggt atgccaagat ggtggacata agtgaaaaag
    79141 atgatactaa aagaacggcc gtagctacag ctacaattac tcttagtaag gaagcattag
    79201 aaaaagtaaa aaatggtcag ataaaaaaag gagacgtatt gtctgtagct caagttgcag
    79261 gtataatggg agctaaaaat acatcttcaa acataccaat gtgccatcag attaaattag
    79321 ttggatgtga tttagaattt gatgtagatg attctatgtc tgctattaag atatacgcaa
    79381 cctgtaaatc tcttgggaaa actggagtag aaatggaagc tttaaatgca tgttctttag
    79441 cagcacttac aatttatgat atgtgtaaag cagttgataa aaaaatggtt ataagtaata
    79501 tccatcttgt ggagaagact ggtggaaaat caggagattt taagttcgag taaattaata
    79561 atatattggg ttaaaatttg gaggaaatat ggcgaaggta gtgtcaataa atataagtga
    79621 gaaaaagggt gtaattaaag ttcctgtaca atgtgcagag ctaaaaataa atcatgggat
    79681 agttggagat gcacatgcag gaaactggca tcgtcagata agcttacttg gaaaagaaag
    79741 catagataaa atgaaaatgg aaggctttga ccaattaaaa tatggagatt ttgctgaaaa
    79801 tgtaactaca gaagggatag aagttttttc cctgcctgtt ggtacaaagt taagaatagg
    79861 gcaatgtgaa gttgaagtaa ctcaaatagg gaaaaaatgt cacaatggat gcgaaattaa
    79921 gaaattgaca ggtgactgtg tgatgccacg agaaggaatt tttgtaaagg ttctaaaaga
    79981 aggaattata aatgtgaatg attcaataga tgtaatctaa tgaagtcact attaaaatat
    80041 aattataagt aaatactatt aagatttaaa tatatatttt aagagagaat taattttaat
    80101 aaaatatttt agttataaat tggaatattg gttatataaa gctatgaatg taaaatcata
    80161 gctttttgtt tttgaatttt aaaatataat attttattta tatatattaa attatatttt
    80221 atataaaatc aattgtttaa atatatatta tttatactgt aaatttatag ataataaagt
    80281 ataaaaaaaa tatattttga tgaaatttaa aaaaatacat tatataaata tagtaatagt
    80341 atgaaaattt acatataaaa ctaaaaaatg caagtaattg actttttaag ttgacaaaat
    80401 attgcatata tattatgata taaatcataa attaactaca aatcaatatg atatattcgt
    80461 agaagaagaa agtagcataa aggaatttta cagagagtta gatttggctg agaactaata
    80521 ttggaattta tgtgaaaagg actttggaga atactattgt aattatgtta gaatagtggt
    80581 ttaattcgcc ttaagaaaat gagtgagtaa aattaatttt tactaataag agtggtaaca
    80641 cggatttata ttcgtctctt ggatttttcc aagaggcgtt ttttattata aacttatttc
    80701 agaaaattta aaactatata ttaaatgaaa attataaaaa tatgatagtt aataaattta
    80761 taaattagaa aattgtaaaa tatgctaagg tcagtagttt tacgatttaa atggagggat
    80821 gaaaatggaa gaagaaaaaa ttaactatgc tctggaacag attccagaga atcaaaaacg
    80881 tggttgggta gctatgtttt cagttttagt agcaataggt gtggatttat catctgttat
    80941 tttaggcgct gagttggcac agagtatgcc aatgaaacaa gcaatattgt cagtaattgt
    81001 tggttcattt ttttctgcaa ttttgtatac tacatgctct ttggttggtt catctacaag
    81061 tttatctaca tctatgataa caaagtatgt atttggagaa gctggagcaa aaatattttc
    81121 tctagttata ggggtttctc tattaggttg gtttggagtt caagtaggtt tctttgctca
    81181 aaatgcacag ataataataa aagatatatt taatttagat gtcagtatgc agattttaag
    81241 cctaataggt ggtctcttga tgatgagtac tgcaatttat ggatataagg caatggagaa
    81301 gttgagtgtg tattcagtac catttttatt agttcttatg atgctaacta tattcttagc
    81361 ttttagagca aatggaattt cagttgatga taatatgaaa tctactatga catttgcagg
    81421 tggagtttct ctgtcaatga gtataataat agttggtgca attgtatctc ctgatataag
    81481 tcgttgggct aaaagtagaa gagactgtgc tctttcaagc tttttgggaa tacaatttgg
    81541 aaatgctttt atgataatag tttcgatagt attagtaaaa tgtatgggaa cttcagatat
    81601 tatgagaatt tttattacat taggaattgc tataccaggt ataatagtac ttacattagc
    81661 acaatggact acaaatacaa gtaatgtata ttcagcatca ttaagtatag ctcttgtact
    81721 taagaaggct cctgagaaag tattaactat agtccttggt attatagcaa cattattggc
    81781 tgtatttgga atatatgaag gttttatagg atttttaaat ttacttggaa ttgtaattgc
    81841 acctgttggt ggtgtatata cagcagaata ttacatagta aagcaagaac ttaaaggctt
    81901 tgataaagga gtattatata aaccaatagt taaacgttca atagtgtctt ggataattgg
    81961 tatattaata acttaccttt caacatatgg atttataact cttactacta tagcaccttt
    82021 agatggtttt atagcagggt ttgtagtaca atctattatt ggaaaagtgc tttgttcaac
    82081 aaaaaataag caagaaatag acaaagcagt ataaagaaat ttgtttataa agtataaaat
    82141 aaattagaaa tatgaggaga aagtaacatg agatttttaa cagaagaaag tgtagataaa
    82201 atagcagttg gtgcagcagt gcttggaact ggaggtggag gtgacccata tgtaggtaaa
    82261 ttggttgcaa aacaagccat taaaaagtat ggtcctgtaa aagtaataag tttagatgaa
    82321 cttgatgatg atgctttggt agttccagta tctggtatgg gttctcctgt aattacaata
    82381 gaaaaattac tttcagaagt agagttaact acccctttag aaataatgga gaaattatta
    82441 aatagaaaag tggatgttat aattcctata gaaataggag ggataaactc acttatgcct
    82501 atagcagttg ctgctaaaaa aggacttcct atcttagatg cagattctat gggtagagcg
    82561 ttccctgaag ctcaaatggt aactttttat cttgaaggat atgaggcatc tcctgccgta
    82621 atgtctgatg aaaaaggtaa ttctgccatc ctttatcctg tggatggaat ttggtcagaa
    82681 agattagcta gaactttaac tgtagaaatg ggaggaagtt cttctattag tgactataat
    82741 ttaagtggag ctcaagttaa aaaagctgct ataggtaata ctcttacaat agctgaaact
    82801 ataggagggt ttttacttga aaataaatct gattcaaaag gtgctgttga gaatatacta
    82861 aaagaattgc atggatacaa gttatttgaa ggaaaagtaa ttgatattaa gagagagttg
    82921 aaaggtggat ttactagagg acatgccttt tttgctggga ttaatgagta tgatggagag
    82981 tattctatat tattccaaaa tgagaattta attgccaaaa aaggtgatac accactttgt
    83041 attacaccag atttaatagc agtattagat ttagaaactg gatttccaat aactacagag
    83101 agaataaaat atggttctcg tgttatggta gtagcttttc cttgtaatga aaagtggaga
    83161 acagaaaaag gaattgagac agttggacct ggatactttg gatatgatgt ggaatataaa
    83221 acagtagaag aattacaagg aaaataaaag tttaggagga aattttgatg tatcgtgtag
    83281 gaattgacgt tggaggaaca aatacagatg cttgtatact ggatggggaa ttaaaagtaa
    83341 ttcattcagt taaggtggca actacaaaag atgttgaaac tggtgtttac aatgccttaa
    83401 aaaaagttat agatgaaagt aagattgacc attcattaat aaaatatgct atgcttggta
    83461 caactcattg tacaaatgct attgtagaaa gaaaaagact taataatgtg gctatgataa
    83521 gaataggaaa gccagccact actgccattc ttccatttat agattggcca gaagacttaa
    83581 gagaaaaaat agaattagat tcaatattgg tatctggtgg atatgagttt gattaaaaaa
    83641 tagctacgca cactcgtgac tttagtcatg agttagtagc taaaatagtc agcatatagg
    83701 gaaacctata tgtagagata gga
//
LOCUS       DAFAZV010000016        79360 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFAZV010000016 DAFAZV010000000
VERSION     DAFAZV010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 79360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79360
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.016"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(383..1105)
                     /locus_tag="KOU88_001606"
     CDS             complement(383..1105)
                     /locus_tag="KOU88_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004398740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK3211503.1"
                     /translation="MITIKNLSKSFGDLNVLKNIDLEIAKGEIMVIVGPSGSGKSTLL
                     RCMNLLEIPTGGEIIFEGKNLVDKKTNIDEVRQNIGMVFQNFNLFPHKTILDNITLAP
                     IKLKKMTKEEAEKKAEILLSRVGLLDKKDSYPSQLSGGQKQRIAIARALAMEPDMMLF
                     DEPTSALDPEMVNEVLDVIKELAKEGMTMAIVTHEMGFAKEVADRVIFIDGGSILEDN
                     TPEEVFGNPKHERTKAFLAKVL"
     gene            complement(1164..1841)
                     /locus_tag="KOU88_001607"
     CDS             complement(1164..1841)
                     /locus_tag="KOU88_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK3211504.1"
                     /translation="MSLDFSFLSRFGTSFLEGTGVTVSISLVALCFGFIIGIIICMAK
                     ISKSKVLRAISSIYIEVLRGTPLLVQIYIVWFGLPQLGIRFPMLFGIPSEFIASAFAL
                     SVNSGAYVAEILRSGIQSVDNGQMEASRSLGLNYWSTMRYIIIPQAIKNILPSLANEF
                     ITLVKESSIISVIGVVEIMRTADIVKNAAFRALEPLIVAAAIYFVITFTLSRLVGLLE
                     KKLSVSN"
     gene            complement(1869..2684)
                     /locus_tag="KOU88_001608"
     CDS             complement(1869..2684)
                     /locus_tag="KOU88_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBK3211505.1"
                     /translation="MKVFKKLLSLGLVLGLTLSLVGCSGGGEKTKLEQIKDNGKLVVG
                     TSAEFPPFEFHKVVDGKDSIKGFDIMLAEEFAKELGVKVEIKDMSFDGLIGALNADQV
                     DIVLAGMSPTPEREKSVDFSELYYLSRNAVIVKDADIDKVKTEDDLKKLRVGVQAGSI
                     QEEYVVNTLKMTTTKSLKAIPDLITELKNGNIDAVVTNEAVSLINVKKYDGIKMANTE
                     VGKDVTEGMAAAIKKSDNNKDFIELLNKKIKELQDGKKIEEFLNEASTEAASN"
     misc_binding    complement(2910..3120)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(3796..5862)
                     /locus_tag="KOU88_001609"
     CDS             complement(3796..5862)
                     /locus_tag="KOU88_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBK3211506.1"
                     /translation="MVELIITTNIDIRKLNENQLEAVEHIDGPCMILAGPGSGKTRVI
                     TYRIANMVVNKNIAPTRILAISFTKASSIEMKNRALNLSDDIRLNKVTYGTFHSVFFK
                     ILRYFERYNLDSIFDEKSKRMTIKAILKSLNIENADDDENIGQVINEISYVKNELMDK
                     NEFNSEVLTKDEFLKVYNLYEEQKSKVNKIDFDDMLIRTYYLLLNNKSALEMVRNVYK
                     YILIDEFQDINKVQFEVLKLICSPLNNIFAVGDEDQSIYGFRGARPDFLLEFEQYFNN
                     TKKIILDINYRSKSEIVHTANRLIDKNKNRYEKIIKCSQGDGGSVTYISPHDSEEEAL
                     YIAREIIDEIQKDYVEYSDFAVIYRTNIQSRALVDVFMDMRIPFVVKDSVITIYDHWA
                     SQDILAYLRIGINPKSNKDWLRIINKPFRYISKDSINMVKDEKDFITALINKCNLHPK
                     QVKTINDLEIDLSYLNTLNPKNAISYIRTSLDYDRYVLDYCSNRKIKTNGLVEILNEL
                     ESSATNFNTVTEFLEHIDRVKTELTENNKNKQTEGVIFTTMHSAKGLEFRNVYIIGVN
                     EGTIPHEKSYDICKEEKKEEQLEEERRLMYVAITRAEEKLCISSTLNKYGKKVDKSLF
                     INDIKSPTKKEIDSIGVGDKVYHKKFHEGEIIKKDGIMFTIKFKDRERILDLKTCLLK
                     NIIYTI"
     gene            complement(5939..8968)
                     /locus_tag="KOU88_001610"
     CDS             complement(5939..8968)
                     /locus_tag="KOU88_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3211507.1"
                     /translation="MENNLRKNNSIMKKMIFPLIIVMLIQTSLFCATILWGGTIKKLN
                     DNSFDILNERVINRKNYIQNEMLQRWSNTSETEATINSSVKKVLNEKNALIEDVGNNE
                     EINKDIIKSISNDLIYLLRKNSVTGAFIILSDKNINDKSIDSKGEISRTGLYIRDLDP
                     KFNPNDNSDLLIERGSSDIARSFGISMDSYWEPKFSFKSENEQDGDDFFYKPFRAAID
                     NPNVSSSNLGYWGSKFLLTNAGDRLMTYTVPLIYEDGTVYGVLGIDLSVNYLRELLPY
                     SEINGNKKGNYILGVDRNNDMAFENVISNGYSLKEKFWDGLHSNLEQKESYKNIYKIK
                     NKDNECGNGNIYASVQYLDLYNSNTPFENERWALLGIIEEKSLLSFSKRVEKLVIISI
                     AISLLIGLIGIYIASRLFTKPIVLLANKVRNSNPSKPVNLDKINISEIDELSSAIELL
                     SANVADSSSKLSQIIEMVDMPIGAFELYKNAENVFCTKEFFSVFTTEIKFEEYGYMEK
                     NKFLKKLRGLDKYLQESYETENTYIYKFESKDKKLKWIRMNIFEDELKVLGVVVDVTK
                     EFIEKRKIEYERDFDILTNLLNRRAFHSQIQEKFKNKDELKIAAFIMWDLDNLKYIND
                     TYGHDAGDEYIRCAADILKKFISWNGIVSRLSGDEFYVFIYGYESKDSIRDIINSVKK
                     QMNNTLLKLHDGTEFKIRASAGISWYPDDSTNYDELMRYADFAMYQIKNTIKGEVSEF
                     DINIYNKDSFLLSNREELNKLIDGQLVEYAFQPIVDCKGKVFAYEALMRPKIKTFSSP
                     IDVIRLARSQSKLYQIERITWFKALKSFKKYKEKFGDCKLFLNSIPNNNLSKVDFEEI
                     EDLYGEYLNRVVLEITENDKINEDFIEKKKAYIDHWNIEIALDDFGTGYNGDAVLLYI
                     MPDYVKIDMSIVRGIDKDENRQKILKNLISYSNERNIKVIAEGVETKGEMETLINLGV
                     DYMQGYYISKPSFIPEDISDKIKKELKICHENRNDVV"
     gene            complement(9021..10481)
                     /locus_tag="KOU88_001611"
     CDS             complement(9021..10481)
                     /locus_tag="KOU88_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK3211508.1"
                     /translation="MNRCKFAKLIITSMIVLLLTGCSLKKEDNYKLDPENPTSIQIWH
                     YYNGQQKMAFDKLVKEFNDTVGAEKGIIVEAFSQGNVVDLSEKVLDSANKKVGSEDVP
                     NIFAAYSDTAYEMDKLGLLVDMDKYISKEELNEYIDEYVEEGRINSKDEFKLFPIAKS
                     TEILMLNKTDWDKFAKATNSNINDIKTIEGLVETSKKYYEWTDSLTKEPNDGKAFFGR
                     DALANYIIIGSKQLGVEIFSVKDGKVTLNIDEKVMKKLWDNFYVPYINGYFASYGKFR
                     SDDAKTGDILALVGSSSGAAYFPDRVMLNDNESYNIETSVFQAPRFKGEGKYAVQQGA
                     GMAVTKSTKEEEYASVEFLKWFTDKEPNIKFSIASGYLPVKKKTNDLDVIKEVMKKDN
                     LSLSDKVEGSIASSIEQINSCNLYTNKAFDGGTKARQILEYSMLDKAKEDSNKINELV
                     KSGTSKKDAVAQFNNDKNFKTWFESFKAELENAIKK"
     gene            complement(10573..10941)
                     /locus_tag="KOU88_001612"
     CDS             complement(10573..10941)
                     /locus_tag="KOU88_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211509.1"
                     /translation="MGNKNTKYKDKTRERYNKKVENLNKEKLNKVNKQSKKVDKIDDI
                     INKSSIVLCVLLVVFSLLYLFKLVQLNIIMILLVITVAIQQGLVSFGAFRNKNYVKAL
                     FSIFVIVCFLIAFKYVVNPV"
     gene            complement(11117..11857)
                     /locus_tag="KOU88_001613"
     CDS             complement(11117..11857)
                     /locus_tag="KOU88_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBK3211510.1"
                     /translation="MLYDEDEKEENNERWLLTYSDLITLLMIFFVIMYSMSNVDAEKY
                     KQLSQSLNSAFGGSSGVIEGGNSKIEPVVEAGSNDLDTLQNAKFKKIGEEIQKYLNEN
                     GMANSVSLRVQDRGLVISLKDTILFDTGKAIVKDNSRDKIIQIGKMLNEMNSYMRVEG
                     HTDNMSIKNSEFKSNWDLSVMRATNVVQLLIDNAGIAPDKLSAVGYGEFRPIAENSSE
                     EGRSKNRRVDIVLVDSKYDNVENVSKDK"
     gene            complement(11878..12666)
                     /locus_tag="KOU88_001614"
     CDS             complement(11878..12666)
                     /locus_tag="KOU88_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein"
                     /protein_id="HBK3211511.1"
                     /translation="MTTLIFFIVGIASLVVAFVIDGGHVGALFVFSSALVVFGGTIGA
                     VGASTPFPVFKKSIKIMLLAFKNKKPNNIENIIYFKEIATKARKEGLLSIDKEISEND
                     ELDPFIRKGLELMVDGVDAVTIRNILESQIQITSKRHKEGIAIFDSAGGYAPTLGIIG
                     TVMGLVHILGNLSSNPDALGPQISVAFLATLYGVGSANLIWLPIASKLKAINQQEVSE
                     RLLVIEAILSILEGDNSNLMTEKLKIFLNSKELIELEEIGGRAE"
     gene            complement(12754..12844)
                     /locus_tag="KOU88_001615"
     tRNA            complement(12754..12844)
                     /locus_tag="KOU88_001615"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12808..12810),aa:Ser,seq:gct)
     gene            13103..13867
                     /locus_tag="KOU88_001616"
     CDS             13103..13867
                     /locus_tag="KOU88_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK3211512.1"
                     /translation="MLPQERYEKILSILKSDNIIKINDIVQMFDISIETARRDLAHME
                     SIGLLKRVYGGAIPVIASSVELNYVKRKKINSNDKKQIAIKCSEFINTNDTIFMDTGT
                     TVLEVSKNLKDKKNLTVITNSILVANELMNTNIKVYVLGGYLRETEGSFSGPLTLSAI
                     EQFNVDKAILGAGGITLENGISDYHLEEALVRKKMIERSRKSIVVVEPPKFGINSFAS
                     VAPIEHIDTIITSASIDHNIIIEFSQKGIPLVIADN"
     gene            complement(14148..15263)
                     /locus_tag="KOU88_001617"
     CDS             complement(14148..15263)
                     /locus_tag="KOU88_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBK3211513.1"
                     /translation="MPFDKIILYIMAVGVLLGALDRIIGNKFGLGEQFEEGFNSMGPL
                     ALGMVGIVCLAPVISDVLGPIIIPIFNLCGADPSMFATILANDMGGYPLAMELAHNKE
                     AGMLAGLVVSSMLGCTLVFSIPVGLGLIEYEDRPFFAKGLLIGLITIPFGGIIGGLIA
                     GFNLSMVIINMIPVIILAVILAVGLKFNSTLMINGSLVFGKFISILITIGLGAAAFQE
                     ITGIVLIKGMTPIREGIQVIGSIAIVLLGTFPILHLLVKVLNKPLTIVGGKLGMDATS
                     AAGLVFTLANSIPVYKMMKDMSPKGKVVNTAWLVCATAALGDHLGFTAGVVPEMITPV
                     VIGKLVGGVLAIALAILMTKDLTLEEEQSIKMKKDAV"
     gene            complement(15304..16830)
                     /gene="glpK"
                     /locus_tag="KOU88_001618"
     CDS             complement(15304..16830)
                     /gene="glpK"
                     /locus_tag="KOU88_001618"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBK3211514.1"
                     /translation="MKYVLAIDQGTTGTRAVLINEKSEFVFSDYMEHTQIYPQSGYVE
                     HDPIEIWNNTKTVSNNVLQQAFENGINESDIKGIGIDNQGETVMLWDKNTGKPLYNAI
                     VWQCRRTYDYVENLKNIPGLENKIIDKTGLIIDPYFSGTKIKWVIDNVKGVKEKIKNG
                     EVLAGTLDSWLIWKMTGGKSFLTDVSTAARTMLFNIRDMDWDRELLDIIGVPRSILAD
                     IMPTSGDFGTTDKEAFCGVSIKITASMVDQPAALFGNGCFEPGMVKNTYGTGCFLYMN
                     IGEELNIAGNGILTTVAWKIGDKVTYAYDGGVYIAGAAIQWLRDGIGVIKNYSETDDM
                     ANSISSTGGVYFVPAFAGIAAPYWDQYARGTMVGITGSTKKEHIVRATLESVALQVKD
                     VVDSMNLASGKKIKMLRVDGGITKNNFTMQFQSDILGIPIEIAENPETTVLGVGYMAG
                     LSCGVWNSIDEIRSEFTISKKYIPNMTTQKREEILLGWNQAVKRAMNWENDTKKVCAN
                     "
     gene            17123..18220
                     /locus_tag="KOU88_001619"
     CDS             17123..18220
                     /locus_tag="KOU88_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBK3211515.1"
                     /translation="MKKTYLFSPGPVMVTDKVRNSLLHYDICHRGNEFMDLFKDTQQK
                     INKLYNATSNYYSLIVSGSGTSVNECVLSSIFDKEDAVLLVSNGVFGERLEEILSTYN
                     VKTYKPNFEWAEYPDLDILEKYIIENSDIKVIAMVFHETSSGMINPVPELGKLAKKYN
                     KIFFVDAISASAGEYIDVEEFNIDIITGVGGKALGAFPGSAYLCAKESILQNIKENQC
                     KNVYLNLYKHYKVAKSSSQTPNTPNVTLIFALNEALTEFLEDDSKIERYKECSAILRN
                     GMEELGLTFLLPDKYMSNTVTSVFLPKEINVNEFILGLERESGYVVYPGKGKFLDANI
                     FQVANMGEIYPEDCYKFLDILKSKLEIKKVI"
     gene            complement(19045..19557)
                     /locus_tag="KOU88_001620"
     CDS             complement(19045..19557)
                     /locus_tag="KOU88_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211516.1"
                     /translation="MKVKKFKSGIVMALTVMAIGASLTNVSAMELNKSKEFETKYNEM
                     KRDFQEEYGKEDKFNITLNDEFTKEEVNGAKGIIKTTNKMNNEVVVLNYFDEMKSGIE
                     FELKPKAEKNAILRDEFQQGYGKEDKFKVVLDDEFTKEEVNGAKGIIKTTDKETGEVI
                     VYNYFDELEK"
     gene            20110..20991
                     /locus_tag="KOU88_001621"
     CDS             20110..20991
                     /locus_tag="KOU88_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HBK3211517.1"
                     /translation="MKKRLIIMILSVVLVLSSILTIFAYSNIKYNNNKLIYSNMIDKK
                     TQNSVKEILKENKINEKDIDTFIKAVNNYNKLQVKILQNNINISKSGYSSINAKQVPY
                     NLEKLQDNWVKKFPDYMDVNCRITAFRLFKDFINSNKKFTGDSIDLNVDLDTIMNNKD
                     AKFSTKDVEKFINFFSAIPAKDTDDTIKIAEQIKNEWKKRKISFKNNKNISIINGFLR
                     YPETKNVFIGHTGICIKTKNGILFLEKYGVTSPYQVTKFKNKEDVKNYMFNRLKISEG
                     EIELPDPIIMENDKLMK"
     gene            complement(21304..22083)
                     /gene="hisJ"
                     /locus_tag="KOU88_001622"
     CDS             complement(21304..22083)
                     /gene="hisJ"
                     /locus_tag="KOU88_001622"
                     /EC_number="3.1.3.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ"
                     /protein_id="HBK3211518.1"
                     /translation="MKDGHIHSPYCPHGSKDDFEKYVQRAMDVGITEMTFTEHFPYAN
                     GFRDPAPENDSCMSIEDLPKYFNDVKKLKEKYEGKIKINVGSEVDFIEGYEEGIKENL
                     NKYGEELEDSLLSVHIIKIDDDYYCVDYSVEEFQNLIDKLGSIEAVYNKYYETLIKAV
                     NSDLGIHKPKRIGHLNLVRKFNQVFPYDYKGNKILEELIKLIKEKGYELDYNVSGNRK
                     EYCKEPYIDGYLLDLVKKYDIPLVLGSDSHCAEEINKYDII"
     gene            complement(22628..22978)
                     /locus_tag="KOU88_001623"
     CDS             complement(22628..22978)
                     /locus_tag="KOU88_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter"
                     /protein_id="HBK3211519.1"
                     /translation="MIFDKEIVRYHHGHHDHDHCHEHTHGDICHEHPHDHAHDHDHEH
                     SHEESSESKDEKTLKILLVHWINHNETHEEGFREWVEKARAIGKEETAKSIEKAIEYM
                     EEANKMLLEAKKHM"
     gene            complement(22994..23410)
                     /locus_tag="KOU88_001624"
     CDS             complement(22994..23410)
                     /locus_tag="KOU88_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3842 family protein"
                     /protein_id="HBK3211520.1"
                     /translation="MIIAVIDGMGGGIGAQIVSSLREELPTYVEIYALGTNSIATSSM
                     MKAHANKGATGENAIVVSAKKANIIVAPISVIIPNSMMGEVTCNISEAIADSEALKIL
                     LPIMPENVELVGLEGKPLALLVKDSVNLIKKEFNIK"
     gene            complement(23429..23620)
                     /locus_tag="KOU88_001625"
     CDS             complement(23429..23620)
                     /locus_tag="KOU88_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CooT family nickel-binding protein"
                     /protein_id="HBK3211521.1"
                     /translation="MCESSAFICKSNNELEKVMENVVNIDPCDGKIYLTDLLGEQKII
                     DGIIKEIRLMDHKIIIQEN"
     gene            complement(23771..24586)
                     /locus_tag="KOU88_001626"
     CDS             complement(23771..24586)
                     /locus_tag="KOU88_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBK3211522.1"
                     /translation="MNQWRVIHNKSYEGAMNMAIDEAIFTAYKKGHNKPTLRFYTWEP
                     ACLSIGYFQKLEDEIDLDKCRCMNIDYTRRITGGRAVLHDNELTYSIIIGEDNPLIDK
                     SINLSYRYISEGLVKGLNLSGIETDNLNRGERISRENLSAACFNAHASYEVTINNKKV
                     IGSAQSRKDGVLLQHGSIILDFDVEKLFKLIKTKTPELKERAMKFTAKKASGIENEIG
                     RKIDIDILQKNIVKGLAEQFNVEFVEGDLTDYEKQLVKELYEKYKNEEYNKKR"
     gene            complement(24633..25571)
                     /locus_tag="KOU88_001627"
     CDS             complement(24633..25571)
                     /locus_tag="KOU88_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3211523.1"
                     /translation="MIRLSVGTAIELGILNKKSDIPPTTAYIMIGEKCINKCSFCSQS
                     IESSTRKDKLSRVIWPEFSKEEILDALKAYKGKNIKRICIQSMASEEAHNSVLDFINY
                     ISGKIDMPISLSAKLENDEQIKKFFSVGVDKIGIAIDAANKELYEKIKGNNYDEKLKF
                     ITEMSKSYPNKISTHIIVGMGESHEDIYNLYTYLKENDVMISLFAFTPVRGTKMEKIS
                     QPSIESYRRVQLMSYMINKGYPKEYFKFKNGYLNSIKLDNDILKDINKGYPFEIRGCK
                     DCNRPYYNERPGSTIYNYSRPLNQSEIDLAIREINL"
     gene            complement(25568..26440)
                     /locus_tag="KOU88_001628"
     CDS             complement(25568..26440)
                     /locus_tag="KOU88_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3211524.1"
                     /translation="MNKNLSEKMKIAFDIKLKNFGNKIEFAYPNQTLALSTTSNQCSL
                     KCAHCNGHYLNNMVPIEEYEEKVQSRNITSFLLSGGCSYEGDVPINTHINTIKNLKEQ
                     GYRLNAHLGLMDKDSIVELCKYLDIVSFDLVFDDETIREVYKMKKSKEDYIEVYNTIQ
                     EHTEVAPHICIGLKGGQIKGEYEIIEYLQKNPPNKLTFIVLIPTKGTEYENVEPPELE
                     GVADILCEARINLPDTEINLGCMRPRGVYRKELDQLSIMCGVNRIVLPSRSAKNKAIE
                     MNMTINECKECCVL"
     gene            complement(26465..28393)
                     /locus_tag="KOU88_001629"
     CDS             complement(26465..28393)
                     /locus_tag="KOU88_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4445 domain-containing protein"
                     /protein_id="HBK3211525.1"
                     /translation="MIKVSFTPNNKEVYCNEGDILLEVARNADIFIDAPCNGNVSCGK
                     CKVKLLNGKVDTEKTRHITDDEWEQGYILACCTKVISDIEIEVPSKVSSSMHGMKIEG
                     SNKKEDREIFERAKKIIEEHNLQFKTNIKKKYIEMEEPNLDDNISDVDRLERYVRNNL
                     GYNEIDFRLDILRKMPTVFRKSDFKVTITYVQKQKKLTIINIEQGNKENSLYGVAIDI
                     GTTSVVVCLVDLYSKEVVDKASSGNAQIKYGADVINRIIYSTKKNGLETLHKAIVEET
                     INPLLKTIYERNGIDKEDVVTLVAAGNTTMTSLFLGVYTDFLRQEPYIPPFLKSPKLM
                     GENVGLFVNDSAYVYLAPSVASYVGGDITAGVLSAGIWSSEENVLFIDLGTNGEIVFG
                     NKDYMMSCACSAGPAFEGGGISCGMRASAGAIEKVIIDKDTLEPTLKIIDECAPVGIC
                     GSGIIDLICQMITKGVIDRRGKIYRDLDNKRVRFNEHEIGEYVLAFKEEFDLENDIVV
                     NEVDIDNFIRAKGAIYSGAYTLVDSLGMDFSILDRVYIAGGIGNNLDIENSIIIGLLP
                     DIDREKFTYIGNSSLVGSYLALISKDAKNKLEEIGNQITYVELSVYPSYMDEFISACF
                     LPHTNIEQFPTAKKLLEE"
     gene            complement(28505..28882)
                     /gene="gcvH"
                     /locus_tag="KOU88_001630"
     CDS             complement(28505..28882)
                     /gene="gcvH"
                     /locus_tag="KOU88_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBK3211526.1"
                     /translation="MKLLPELKYSKDHEWVKVIDGDVVYIGITDYAQDQLGEILFVET
                     PEVEDTVTKGVDFGVVESSKVASDLISPVNGEVLEVNEKLEDEPECINEDPYENWILK
                     VKLADVAELDTLLSDKEYEAGLE"
     gene            complement(28969..31095)
                     /gene="cdhC"
                     /locus_tag="KOU88_001631"
     CDS             complement(28969..31095)
                     /gene="cdhC"
                     /locus_tag="KOU88_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CO dehydrogenase/CO-methylating acetyl-CoA
                     synthase complex subunit beta"
                     /protein_id="HBK3211527.1"
                     /translation="MNLYNIIFTGSEQALGAAQAMLAEAIEKNGKEHKVAFPDTAYSL
                     PCIYAATGQKMNTLGDLEGALEVVKSLINRTHLLEHAFNAGLATALAAEVIEALKYST
                     MDAPYSEPCAGHITDPIIRSLGVPLVTGDIPGVAVVLGECPDAESAAKVIKDYQSKGL
                     LTFLVGKVIDQAIEAGVKMGLELRVIPLGYDVTSVIHVVSVAVRAALIFGGLTPGDLN
                     GLLEYTANRVPAFVNAFGPLSELVVSAGAGAIALGFPVITDQTVLEVPMNLLTQKDYD
                     KIVATSLEARGIKIKVTEIPIPVSFAAAFEGERIRKSDMFAEFGGNRTEAWELVVKKE
                     ATEVEDHKIEIIGPNIDEVDADGVLRLPLAVIVKIAGKNMQEDFEPVLERRFHYFLNY
                     IEGVMHVGQRDMAWVRISKDAFDKGFRLEHIGEVLYAKMLDEFESVVDKCEITIITDA
                     EKVSELKGEAIAKYNARDERLASLVDESVDTFYSCNLCQSFAPAHVCVVTPERLGLCG
                     AVSWLDAKATKELDPTGPCQPIEKGECLDDRTGVWNSVNETVNQISQGAVESVTLYSI
                     LEDPMTSCGCFECICGIMPEANGFVVVNREFASVTPVGMTFGELASMTGGGVQTPGFM
                     GHGRHFISSKKFAYAEGGPERIVWMPKELKDYVADKLNATVKEMTGIENFCDMVCDET
                     IADDSEGVLAFLEEKGHPALAMESVM"
     gene            complement(31152..31958)
                     /locus_tag="KOU88_001632"
     CDS             complement(31152..31958)
                     /locus_tag="KOU88_001632"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBK3211528.1"
                     /translation="MEKFMIIGERIHCISPSIRKALAERDPAPILKRAKEQLEAGAHY
                     IDFNIGPAERDGEEIMTWGIKLLQSEFNNVPIALDTANKKAIEAGLKVYDRTNAKPII
                     NSADAGSRFDLIDIAAEYEAMVIGLCAKEGIPRDNDERMAYCQEILEKGLMLGMEPTD
                     ILFDPLCLVIKGMQEKQVEVLEAIKMMTEMGLLTTGGLSNVSNGCPKHVRPVLDSAFL
                     AMAMANGFSSAIMNPCDPELMKTVKSCDIINGASLYADSFLELNEGGFAF"
     gene            complement(32008..33375)
                     /locus_tag="KOU88_001633"
     CDS             complement(32008..33375)
                     /locus_tag="KOU88_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit gamma"
                     /protein_id="HBK3211529.1"
                     /translation="MALKALDIFKLTPKKNCKDCGFPTCMAFSMKVASGAVEVGKCPH
                     MSDDAIAKLSEATAPLMKALKVGAGASEYELGGETVLFRHEKTLVSRNRYAVSFCTCM
                     SDEAVDAKIANMKKVDYVRIGEQMKVEMAVLEYCGDKDAYLKLIDKIKGSGLEVAYIL
                     ACDDAQVVKEAVEVLKDARPMVYGATKENYKDMIEVVKGASLPLGVKAGSLEELYETV
                     ELIQAAGYKELVLDVTGENIKDTYTNAIQVRRTALKEQDRTFGYPSIVFANRLSNSNP
                     MMEVALSSIFTIKYGSIIVIDDISYAKALPLFALRQNIYTDPQRPMRVEPKIYPINNP
                     DENSPVLVTVDFALTYFIVAGDIERSKVPVWLVIPDAGGYSVLTSWAAGKFGGNSISA
                     FIKESKVEEVTNCKDLIIPGKVAVLKGDIEDNLPGWNVVIGPEESMELPKFLKGYQEK
                     ACQTN"
     gene            complement(33406..34350)
                     /locus_tag="KOU88_001634"
     CDS             complement(33406..34350)
                     /locus_tag="KOU88_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA decarbonylase/synthase complex
                     subunit delta"
                     /protein_id="HBK3211530.1"
                     /translation="MAFKMSTQKYSGKISEVEVGIGEKAIKLGGENVLPFYSFDGEVG
                     NSPKIGIQISDVYPESWTDSYKELYKDVANCPVEWAKYVEANTQADFICLKFDGSDPN
                     GLDKSVDECADVAKAVIEAIKLPLVVAGSGNHEKDGKLFEKLAQTLDGHNCLFMSAVE
                     DNYKGVGASAGMAYAHKVGAESSVDINLAKQLNVLLTQLGVKGENIVMNVGCSAVGYG
                     YEYVASTMDRIRLAAFGQNDKTLQMPIITPVAFEVGHVKEAIAPIEDEPDWGCPEERT
                     IAMEVSTAASVLVGGSNAVILRHPKSIETIKELVNALA"
     gene            complement(34370..35140)
                     /locus_tag="KOU88_001635"
     CDS             complement(34370..35140)
                     /locus_tag="KOU88_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3211531.1"
                     /translation="MGYNIAVAGKGGTGKTSLTGLLIDYLVKDKKGPVLVVDADANAN
                     INEVLGIEVEATIGEIREEVNQREKLGNAFPGGMTKAQYLQFRLNSIIEEGEGYDLLV
                     MGRSEGEGCYCFVNGILREQVNKISGHYKYLVMDNEAGMEHLSRKVTRHVDTLLLVSD
                     CSRRSIQAVARIRDLAEELKLSVGRILLIVNKVPNGVMNDGVKEEIEKHNLELIGVVP
                     MDELIYEYDSTGIPLVNLPEDSKSKVAMKEIFAKLELK"
     gene            complement(35196..36581)
                     /gene="lpdA"
                     /locus_tag="KOU88_001636"
     CDS             complement(35196..36581)
                     /gene="lpdA"
                     /locus_tag="KOU88_001636"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBK3211532.1"
                     /translation="MKIVVVGGGPGGYVAAIKASMLGADVTVVEKRRVGGTCLNAGCI
                     PTKALLASSGVLNTVKEAKDFGIEIDGTIKPNFTAIMERKNKVVNQLISGIEFLFEKR
                     GVNLVNGFGKLIDKNTIEVTKDDGTVETIKADKIILANGSVPVVPRMFPYDGKVVITS
                     DEVLGLEEIPESMLIVGGGVIGCEIGQFFRALGTEVTIVEMVDQILLNEDKDVAKQLL
                     RQFKKDKIKVITGIGVQTCEVVDGKAVATLSNGKVIEAQYALVCVGRRPNLDNSGVED
                     IGIEMERGKVVVNEHLETNVEGIYAIGDIIDTPFLAHVASKEGIVAVENALGKTKVVD
                     YRAIPRCVYTEPEVAGVGKTEKQLEAEGVEYNVGQFDFRGLGKAQAIGHFQGFVKVIA
                     DKETDKIIGAAVVGPHATDLLTELSLAVHLGLTVEQVGDAIHPHPSLSEGLMEALHDV
                     HGECVHSVPKL"
     gene            complement(36625..37506)
                     /locus_tag="KOU88_001637"
     CDS             complement(36625..37506)
                     /locus_tag="KOU88_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBK3211533.1"
                     /translation="MSLLRETLESGKFAVTTEMAPPKGTDLSHLIECAKPLVGRVHAA
                     NVTDFQSAVMRATSLATCKLLKDAGLEPVIQITGRDRNRIAIQGEMLSAGVFGINNLL
                     ALTGDHTSVGDHPQAKGVFDLDSVGILQTAETLMAGTDMAGNKLKGSPDFYLGASVTP
                     EYSPIEVQLLKMKKKIKAGAKFFQTQALYDINTMRKFRELTRDMDCKVLAGIVPLKSP
                     GMAKFMTANVPGIFVPDEQIERLRAAGKENWVSEGIKMAGELIKQLKEEDLCDGVHIM
                     AIGAEENIPAILDAAGL"
     gene            complement(37541..38215)
                     /locus_tag="KOU88_001638"
     CDS             complement(37541..38215)
                     /locus_tag="KOU88_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase C-terminal
                     domain-containing protein"
                     /protein_id="HBK3211534.1"
                     /translation="MIISENKPLEEVLGYLKDFDKLVLVGCNQCAATCKSGGEEEVLK
                     MKETLEGEGKKILGYVMLDPACNLLKSKKDLKALKEETKEADAVLSLACGDGTQTIVK
                     NLKDKPVYPANNTLFIGEVQRVGEYEEACKACGDCELGWTGGICPVTMCAKGLMNGAC
                     GGAKNGKCEVNSENDCAWIKIYERLEAIGQLDNLAEIRPPKDYSKQNNPRSLSAKKKK
                     EAAANS"
     gene            complement(38252..39124)
                     /locus_tag="KOU88_001639"
     CDS             complement(38252..39124)
                     /locus_tag="KOU88_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="HBK3211535.1"
                     /translation="MEGMSTKGQIIKGKPVADKISEELIKEVDLLIKEGINPKLTIVR
                     VGARSDDLSYERGALKRCQNIGITTEVLELAEDITQEEYIDVLKRVNDDKNVNGILCF
                     RPLPKHLNEEVIKYVIAPEKDVDCFSPINSAKVMEGDKSGFPPCTPTAVVEILKHYNV
                     DLKGSKVTVLGRSMVVGKPVSMLLLSEHATVTICHSKTKNLSGVAAEADVLIAAIGRA
                     KMVDESFVKDGAVVIDVGINVDEEGNLCGDVDTNAVLDKVSMITPVPAGVGSVTTSIL
                     AKHVVKACKLQNNK"
     gene            complement(39216..39848)
                     /locus_tag="KOU88_001640"
     CDS             complement(39216..39848)
                     /locus_tag="KOU88_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclodeaminase/cyclohydrolase family protein"
                     /protein_id="HBK3211536.1"
                     /translation="MKIADKTCVDFVEVLSSKEAVPGGGGAAALVGAIGMALGSMVCN
                     LTIGKKKYAEYEESVKEILSKAGKLEKDLLKMIDDDAECFLPLSKAYGLPKETEEEKR
                     IKAETMEKALKVACEVPLNIVRVCYEAIKLHEDLVDKGSRLAISDVGVGVQCLRAAIL
                     GGQLNVVININSIQDKEYVNKVKTEVDKLVEDGVKICDEVYAKVEKALGK"
     gene            complement(39953..41629)
                     /locus_tag="KOU88_001641"
     CDS             complement(39953..41629)
                     /locus_tag="KOU88_001641"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014355320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBK3211537.1"
                     /translation="MGFKSDIEIAQEAKPQDIREVAKKLGLGEDDVELYGKYKAKVDY
                     NLLKRETGKKAKLILTTAINPTPAGEGKTTTTIGVADAFAKLDKNVLVALREPSLGPV
                     FGVKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMLDNHIHQGNALRIDPK
                     KITWRRCVDMNDRQLRNIVDGMGKKGDGAVRQDGFDITVASEIMAAFCLASDISDLKE
                     RLGNIIVGYSYEGEPVTARQLKANGAMAALLKDALKPNLVQTLEGTPSFVHGGPFANI
                     AHGCNSVIATRMAMHFADYVITEAGFGADLGAEKFLDIKCRMANLKPDAVIIVATVRA
                     LKYNGGVAKADLNNENLEALEKGLPNLLKHVENITQVYGLPAVVAINRFPLDTEAELK
                     LVEDKCKELGVNVALSEVWAKGGEGGIAVAKEVLRLLDEEENNFRFCYEDDLSIKDKI
                     NAIATKIYGADGVDYTPEADKEIANLEKLGFTKVPVCMAKTQYSLTDDQTKLGRPTGF
                     RITVRQATISAGAGFIVALTGEIMKMPGLPKVPAAEKIDVDENGVIAGLF"
     gene            complement(41878..42657)
                     /locus_tag="KOU88_001642"
     CDS             complement(41878..42657)
                     /locus_tag="KOU88_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3211538.1"
                     /translation="MKIAITGKGGVGKTTFSSMLSRMFAEDGYRVVAVDADPDANLAL
                     ALGFPKEVYESIVPISEMKKLVSDRTAASVGSFGKMFKMNPKVDDIPENFCKEYNGVR
                     LLTLGTVDSGGTGCVCPEHVLLKRLCSHLILQNKDVVVMDMEAGIEHLGRGTAQGVDA
                     FIVVVEPGERSLQTYRKVKKLGHDIGVNKVFVVGNKIRNKEDEEFIIQNLEDGESLGF
                     IYYNQDVIDSDRANQSPYDSSETTKEQIKAIKDKLMSLKDK"
     gene            complement(42967..44886)
                     /gene="cooS"
                     /locus_tag="KOU88_001643"
     CDS             complement(42967..44886)
                     /gene="cooS"
                     /locus_tag="KOU88_001643"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBK3211539.1"
                     /translation="MDEKMLTIDLNSQKMIAKAREEGVETMYDRKEGFKAQCGFGLQG
                     VCCRICGMGPCRISPKTPRGLCGADEHTIVGRNFARMVAGGTAAHSDHARDIAHTLAL
                     ADPNGNYKIRDEAKLITLAKEWDVETEGRDIYDVAHEVAEIALMEFGKPFGTLRFIKN
                     APEPRQKIWKEYAIEPRAIDREIATIMHSTHIGCTGDIDSLIHMSLRTSMADGWGGSM
                     IGTRLSDILFGTPVPRRTEANLAVLEENKVNIILHGHEPALSEMIVLASEEPDLVALA
                     KEVGADGINLAGMCCTGNEITMRHGVKIAGDFHQQELAIITGAVEAVIVDVQCIFPAL
                     ARVADCYHTKFVTTSPKAKITGSTYIEFREEQALDDAKAIVKEAILNFKNRDKSKVLI
                     PELKSGATVGYSVEAVVNQLDRVVNSHIDPAGTVKPLTDCLKSGVLRGAAGVVGCNNA
                     KGVSNEAHVTIMKELIKNDIIVVTTGCGASAAAKFGLMESDAAEKYAGKGLATVCKLV
                     GIPPVLHMGSCVDISRILDLVGAAANYLDMDMCDLPVVGIAPEWMSEKAVAIGCYVVA
                     SGIDTYLGIMPPIAGSSRAVDILTSELKDKVGATFTVNTNPKELAATIIEDIEKKRVH
                     FEALVEEKMAEKAEA"
     gene            complement(45493..46404)
                     /locus_tag="KOU88_001644"
     CDS             complement(45493..46404)
                     /locus_tag="KOU88_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBK3211540.1"
                     /translation="MIKKLDDILEQLKGGEKIVLSVAAAHDKEVLMAIKDAVERNIIT
                     PILVGNEGKIREISKEIGFDLSGIKIVDKDDIKECAEIAVKLVSSKEADFVMKGLLDT
                     SVILKEVLNKDYGLRTDSLLSHVMVYELEKYHKLLITTDGGMNIAPDYEQKAKILKNS
                     IKAAKALGMETVKVACLAAKEKVNPKMQATVDADMLAKACKEGEFGENVIVEGPLAFD
                     LAVSKEASEIKGFKSEVSGDVDIILVPTIEVGNGIGKAFTYMADSKSAGIIMGAKAPI
                     VLVSRADSHESKLYSIAYGAIVAKNMK"
     gene            complement(46520..47098)
                     /locus_tag="KOU88_001645"
     CDS             complement(46520..47098)
                     /locus_tag="KOU88_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBK3211541.1"
                     /translation="MNINEFLTHINQRKPVSSKSEIHEFMVKLSNEAMKITSKLNSSY
                     HEPEEVRSLFSELIGKKVDESFFMFPPFYTDCGKNITIGKNVFINSSCHFQDQGGIEI
                     GDNTQIGHNVVLATLNHGIAPEKRGTTYPSPITIGKNVWIGANVTVVPGVTIGDNAII
                     AAGAVVTKNVAENTIVGGVPAKLLRVIDEIPE"
     gene            47324..48247
                     /locus_tag="KOU88_001646"
     CDS             47324..48247
                     /locus_tag="KOU88_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3211542.1"
                     /translation="MEIRVLRYFLAIAREESISGAATFLHITQPTLSRQIMELEEELG
                     VKLLVRGNRKITLTNEGRLLHKRAEEIISLVDKVELEFDNPNEIISGDIYIGSGETEA
                     MRLIARTAHHFHQKYPNVRYHLFSGNADDVTEKLDKGLLDFGILIEPANIQKYDYAQI
                     PATDVWGLLMRKDSALASQSTINPKDLCNIPLIISRQTLVDKAISKWLQDSNEKLNII
                     ATYNLVYNASLLVEEGLGYALCLDRLVNTTENSNLCFRPLSPPLEAKLNIIWKKHQIF
                     SKAAEKFLLQIQKDFSSIMLDTSKLDTPKEK"
     gene            complement(48419..49561)
                     /locus_tag="KOU88_001647"
     CDS             complement(48419..49561)
                     /locus_tag="KOU88_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK3211543.1"
                     /translation="MDFKIEKYLLKKAEELAFITIKHGGEFKLKSYEVPKGGLDVPIK
                     NEVLVKGIKEKTAQDKLNSMSIADAMIYIIGIDSKFKNNAEYEKFLNALSKDIDLDLK
                     SYMGYMSRKYFEIGEHTDSLIYIKAFITMYPDDLDAMYNYAIVCQEIAKQYQKDMDDK
                     AMNAFLLEAMAKLEKVIDVDENFALGYYHLGYHYYNQGQYLKTKLTWEEALRLGLDAD
                     LVAEVQENLGKMDFKVQYEEGYTLVFQGKFKEGLEKLLPLEEEHMDWWNLLFMIALGY
                     KGMGEIEQAKMYLEKILIIKPNQVDTIVELGLCEAYKNNLDKAIEYFEQAAKIKEDPE
                     ILCNLGMAYLNNGDIDDATYYIERAYELNPQDEITIACLRELRINK"
     gene            complement(49579..51333)
                     /locus_tag="KOU88_001648"
     CDS             complement(49579..51333)
                     /locus_tag="KOU88_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B12-binding domain-containing radical SAM
                     protein"
                     /protein_id="HBK3211544.1"
                     /translation="MKILLTTLNSKFIHTNLAIRYLKEFVRDLIEVNMKEYTINNDLD
                     YILKDIYKNEYDIILFSTYIWNVGDIVKLCDNLKKIRPNTKIALGGPEVSYDSYEAMK
                     KYDFVDYILYGEGELIFRDLVLHLQGKMEINDVNGLVYRQGNEIIVNKPMELLQDLDE
                     IPSPYENLNPKEYENRIVYYESSRGCPFNCQYCLSSTIPGLRYFSLDRIKSDLKALID
                     ARVSQIKFIDRTFNANRKVAMEIMDFLMKNDNGYTTYHFEVTAYLIDDKMLEFLADCK
                     EGLFQFEIGVQSTNEKTLDAVGRRDDFKKLSHVVQTVASYRNIHQHLDLIAGLPYEDY
                     KSFENSFNDVFNLGIEHLQLGFLKMIKGTGMRKVADEHGFKYKDYAPYEFLYNNYISY
                     EETLKLKDIEDILERYYNSKNFVLSMRYIIGRFYKKSPFKFFEVFAKYFDENGYFDLA
                     QGKNQLYKILMDFYNEKINIDNDVFNDILKYDYISLGKTSNIPQFFNKLDVDDFKNRC
                     HVFLQDNDNLSTYLPSFVDKPAKHIIKYVHFEPFRFNVVDLKNDINTEIREVENVVLF
                     EYDDKKIFEKSKTHKVEI"
     gene            51469..51675
                     /locus_tag="KOU88_001649"
     CDS             51469..51675
                     /locus_tag="KOU88_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211545.1"
                     /translation="MELIEKVSINSLSKRDLLLIIKSLEYTNENTQISDFIDLRNNIV
                     KELCFLTDTKEKDFLDYLEKNSTL"
     gene            complement(51680..52603)
                     /locus_tag="KOU88_001650"
     CDS             complement(51680..52603)
                     /locus_tag="KOU88_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211546.1"
                     /translation="MNDELLKKVYTSSFSSASRALKDLTIINTKSLIDDKTQRCVYID
                     ENRLRDELIYYRFYGEKIGNINFLNILLPLILSNTNIQKSEDEVIKLIKKYVIYFKKE
                     ELLFDYLLGSVVYNSIMHNLINNSKIEYVELLQSIKDKIIGFSIELDKSDVVKFQMAR
                     IKAIQLIDKYIDLKSEDYDEESILLNVLNVLYDVYMEDRTVENEGINSIKKSILSILG
                     EDSKLNEDNIDFIFSMSEYVVKLRKYKIGVKAYNKSIDPRSLIRLEEGNTIIDPIFNQ
                     ITVMSKTFNDNILSIKINSKSGIYILKFKKV"
     gene            complement(52857..54557)
                     /locus_tag="KOU88_001651"
     CDS             complement(52857..54557)
                     /locus_tag="KOU88_001651"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBK3211547.1"
                     /translation="MQDFKVAISNCLKEKIEDLSKEEIEALIEVPPNKDMGDYAFPCF
                     KLAKVFRKAPNMIASELAESIEPSGEITKVIQLGGYVNFFVNKSQLAETVIKKVLDEK
                     ENYGHSDFGKDKTVIVEYSSPNIAKPFHIGHIRTTVIGNALYKIYDSQGYKTIRINHL
                     GDYGTQFGKLIVAFKKWGEKEVVESNPIPELLKLYVRFHDEAEQHPEMEDEARAWFNK
                     LENGDEEAQELWQWFRNESLKEFNRVYKLLDIEFDSLAGESFYSDKMNRVIELLEEKN
                     LLKESKGARIVDLEEYKMPPALITKNDGSTLYMTRDLAAAIYRKETYDFDKCIYVVGS
                     QQNLHFQQWFKVIELMGYDWAKDLIHVGFGMVALEEGTMSTRKGRVVFLEDALNQAID
                     KTKEIILAKNPNAKNVDEISKQVGVGAVVFQELSNSRIKDYTFSWERTLSFDGETGPY
                     VQYTHARCCAVLRKAEVEVTSDIDYSLLADEDSAEVLRVIESFNKNILLALKKNEPHI
                     VTRFMLDLAQAFNKFYHDNPILVENLEIRKARLALVLATKQTLENSLKLLGMHAPERM
                     "
     gene            complement(55019..55432)
                     /locus_tag="KOU88_001652"
     CDS             complement(55019..55432)
                     /locus_tag="KOU88_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBK3211548.1"
                     /translation="MILVSACLIGINCKYSGDNNDNEKVKEYLKGKEFTLVCPEQLGG
                     LSTPRPPAEIVDGKVITKDNKDVTENFVRGANETLKIANLYVCSEAILKEGSPSCGCN
                     LIYDGSFSGKKIPGKGITARLLEEEGIKVKSEKDL"
     gene            complement(55500..57878)
                     /locus_tag="KOU88_001653"
     CDS             complement(55500..57878)
                     /locus_tag="KOU88_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBK3211549.1"
                     /translation="MNEKSLRVLEYNKIIDLLKKKASSSLGLKYIENLVPNTDFVEVK
                     SMLEETSEAQSIIIKRGSVGLEGIHDIEDKVKRAYIGASLDPGSLIMIADTLRVARRL
                     RNSLSSSDEEDFNYPIIQSLSNSLYVYKDIEDQIYNAIISEVEISDNASSTLRDIRRR
                     IAQKNQSIRSKLNSIISSTTYQKYLQDAIISLRGDRFVVPVKSEYRSQVAGIVHDQSS
                     SGATLFIEPMTIVEMNNELRQLKLGEQEEIERILSELSAMVGEVSEDLISNQEILGRL
                     DFAFSKGKLSIQMRGIEPTLNEDKYLNIKNGRHPLLDKKKVVANTIYLGRDFHTLVIT
                     GPNTGGKTVTIKTVGLFALMTQSGLHIPADYGSSMCVYDNVFADIGDEQSIEQSLSTF
                     SSHMTNIVSILQNVTADSLVIFDELGAGTDPVEGAALAIAVLEDINSVGAKCIATTHY
                     SELKNYALTKPGVENAAVEFDIETLSPTYKLLIGVPGKSNAFEISRKLGLSDYVISRA
                     KEYINTENIALEDVLQNVEKNRIKAVEDREEAERLKEEIEKLKVEYDEKLEKLVSQRD
                     KMIEKAKSEAFSIIRQAKEEVDIIIKELRSLEQERASKEKNRKIEELRKELTSSMGSL
                     QPTVKSMIVPKVSNKEIKDLKPGEEVKVITLNQNGSVVSVDKKRKEAVVQIGIMKMTL
                     PFKSLQKTRKDVSTNVTKSTRNIIRSKSGSVKNEVDLRGLNLEEAIMEVEKYLDDAYV
                     AGLESVTVIHGIGTGVLKAGLQDILRRNRHVKSQRGGQYGEGGAGVTIVKLK"
     gene            58197..59648
                     /locus_tag="KOU88_001654"
     CDS             58197..59648
                     /locus_tag="KOU88_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-histidine dipeptidase"
                     /protein_id="HBK3211550.1"
                     /translation="MGNVLEGLKPESVFKNFEKISQIPRGSGNEKGISDFLLSFGKNL
                     GLETIQDESLNIIIRKPATKGYENCPGVVLQGHMDMVCEKEKNVEHDFLKDPIKLRID
                     GDMIYATGTTLGADNGIAVAMGMAILEDNTLEHPALEVLVTVNEEDGMNGADALDPSL
                     IKGQYILNMDSEEEGYLLVSCAGGKTCVVSLPVEYKEVKGDKQGLLVEVTGLLGGHSG
                     MEIVLQRANANKAIARVLSVLNVDYELASVDGGTKHNAIPREAKCVIAVNKADVESAK
                     KQINDILTAFKHEFTTSDPGMTYSVAETSVDKVLTKDCKEKVVQMSCLTPHGVQSVSL
                     DIEGLVESSTNFAIIETKESTIEFLTSVRSSVMSIRDEIADRIRLLAQALGANYDLIA
                     QYPAWEFKKGSKLEKICSETYEKLTGKVPTVMALHAGLECGLLLDKLPHAEAISIGPD
                     MFDVHTPNEHVSIPSVANVWDYVIEILKSMNQY"
     gene            complement(59852..62364)
                     /locus_tag="KOU88_001655"
                     /pseudo
     CDS             complement(59852..62364)
                     /locus_tag="KOU88_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436881.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            complement(62587..63408)
                     /locus_tag="KOU88_001656"
     CDS             complement(62587..63408)
                     /locus_tag="KOU88_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK3211551.1"
                     /translation="MIDINLEKCVGCGMCESDCLVNAIKVKDDKAKVKNILCINCGHC
                     MAICPTDAIEMQGFDKNEVIEYNRESFELEPEKLLNFIKFRRSIRQYKDIEVEEEKIK
                     NIVEAGRYTPTGGNRQPIRYILVKEKLKEVKELAIQGLYNLALDTDDNDPVRSIYKNT
                     FKKMYKRYKENGNDSLFYDAPLLMVVVGDMSLGGSAYVDGGLAASNMELMAYSQGLGI
                     CYNGFFVMASNVEPKIKELLGMSENEAVITSFILGYPDVKYKRTVNRNTAKFEVR"
     gene            complement(63926..64402)
                     /locus_tag="KOU88_001657"
     CDS             complement(63926..64402)
                     /locus_tag="KOU88_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HBK3211552.1"
                     /translation="MKLTTICYIEKDDKTLMLYRNKKKDDIHEGKYVGVGGKFEQGET
                     PEECVIREVKEETGLTLKSLSYKGLITFPKFKDEEDWYMFLYFSDEFEGELSEKDLND
                     CKEGNLIWVDNDKIFDLNMWEGDRLFLNWAKTGNIFSAKIVYDNGKLKDYNVSFLD"
     gene            complement(64436..65014)
                     /locus_tag="KOU88_001658"
     CDS             complement(64436..65014)
                     /locus_tag="KOU88_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK3211553.1"
                     /translation="MREEALEILFKYLETDRMRKHCYAVEAVMRELAKRLEPEKEEEW
                     AVAGLLHDLDSDIVGRKPGEICEGHATTTVELLKKENFGDEEMYRAILGHHDGMGVTR
                     TSLMEKAIYAADPITGFITAIALVYPDKKLTSVKTKSVIKRMKETRFASNVNRDAMRS
                     IEDIGIPFDEFAELSLNAMKNISDVLESAENN"
     gene            complement(65118..67718)
                     /locus_tag="KOU88_001659"
     CDS             complement(65118..67718)
                     /locus_tag="KOU88_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBK3211554.1"
                     /translation="MKKIELLAPVGSFDSLKAAVQNGANAVYLGGKDFSARASANNFD
                     RNELIEAVKYSHIRGVQVFVTVNTLIKQYEIEDFVEYVKFLYDIDIDALIVQDIGMAR
                     LIKKLLPDFELHASTQMVAHSLEDVKYLQSVGFDRVVLARELNVDEIKWICENTTVDI
                     EVFVHGALCVCYSGQCLMSSMIGNRSGNRGRCAQPCRQKYELIDINTGEVVKSNGDYL
                     LSPRDLSTIEDLDKIIEAGVLSLKIEGRMKKPEYVATVVSGYREAINEFVDKKKISIS
                     EEIINNLYTIFNRKFTKGYILGEVGKDIMNSNRPNNQGLYIGKVLDYNRKNKRLRVML
                     ENTLKKGDGINLGGGTIGRIIKDGEITTIAHKGDLIELDFVGEAKRNQLIYKTSDSEL
                     MDRVQATFQQDKEFIKTNIRAKVSIKLGKKPELFISDFCGNKSVVEGDKIVEKAIKVA
                     LSKEKIETQIQKLGNTPYKLKEIEIDLDEGVSMPISVLNQMRRDCIELLDEERIKIKD
                     RKFKKNRLKYQPNRVNKQKKLDTVPKIRVKVKNLEQLEAVLNYNVDLIYYEDINTLSK
                     ALQMVSSISIDSNISIDSSISMDLDTSSSLDTPKELMGSNTNNIDTLSNTSKIDTLNK
                     NHYNTAVTNKKLIYSAPRIVRNKEYKQFEILDNIKGINKVQIGNWGSMEYFKKKDLNI
                     DCYLNAFNSESINHFKEEGASTVCLSQELNLNEIKQTLKYTDVEIEAVIYGYAPMMVT
                     EYCPMGVVVRDCKKDKRVAKCKESSYALRDFTDASYRITQDIFCRSTIYNSKVTCMLD
                     NLYELEEIGIDVFRIDFTVEDSEMVKKVIEAHIEVLSNNYKLGKKATDLYKKLDEIGT
                     VAGHYYKGVE"
     gene            complement(68171..68854)
                     /locus_tag="KOU88_001660"
     CDS             complement(68171..68854)
                     /locus_tag="KOU88_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBK3211555.1"
                     /translation="MTSKSQMSESFFLCSLLAITGGFLDIYTYVVRGKVFANAQTGNI
                     VLFGLNIAEGNVKESFYYLIPILAFMLGVFIAEKIRKYFTNNKTKIHWRQVIIIIEMI
                     TILIVSFIPRGRFNMFVNVAISFICSMQVESFRKVNGNSFATTMCTGNLRSATETLFH
                     YIHTKNIFMIKKSLQYYAIIIFFISGAILGTFFTKIFVEKSILICFFILAVVFGIMFI
                     NKDDSFNEN"
     gene            complement(69074..69664)
                     /gene="zapA"
                     /locus_tag="KOU88_001661"
     CDS             complement(69074..69664)
                     /gene="zapA"
                     /locus_tag="KOU88_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBK3211556.1"
                     /translation="MNKVMVKIHGAEYPMVGDKSEKFMISIADFVDKEMDKITRQNPK
                     LSLSVAAILTALNISDLLFECSDENEKLIKANEELSKKVGASNEELQLEIKSLKLTIA
                     EKEAENREAETKMKELIEIIENKKQEIFELSNTTEGSRAELDAYKNKIEELSTQLEEA
                     NERATIAENLASEFQNKAYDLQLKCTGLNNDAKNVE"
     gene            complement(69689..72082)
                     /locus_tag="KOU88_001662"
     CDS             complement(69689..72082)
                     /locus_tag="KOU88_001662"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBK3211557.1"
                     /translation="MLVSLKWLRDYVDIDMDVKEFADKMTMTGTKVETIDYYGEEIEN
                     ILVGKILEIKQHPNADKLVVTKVDIGDKVVQIVTGATNISEGDYIPVAVNGSKLPGGV
                     EIKQTDFRGELSDGMMCSAAELGIDEHYIEEYKRGGIYILDHEDSYELGKDIKDVLGL
                     KDALIDFELTSNRPDCKCMMGIAREAAATIGTKVKYPEIEVKESDEEIDFKVEIDNPD
                     LCRRYVARMVTDVKIEPSPYWMQRRLTEAGVRPISNIVDITNFVMLELGQPLHAFDIN
                     QVETGRIVVRNAKDGEKLVTLDDVERTLDKDMLVITNGEKSLGLAGVMGGANSEITSN
                     TKTVLFESANFKPENIRMTAKKVGIRSEASSRNEKDLDPNLAEIAANRAAQLVEMLGA
                     GKVLKGVVDVYPNKPEPKKLVVNPQRINHLLGVDVPMEQFVGILESLEFKCNLVANDK
                     LEIDVPSFRTDMEQEADVWEEIARIYGFENIPSVQLEGNTTAGIKTSKQKFMDALKDN
                     STAVGLNEILTYSFVSPKGVDKIRVPEGNAKRNFVKLLNPLGEETSVMRTTLIPNMLD
                     VLSTNVSHKIEEVSAFECGHIFIPQDSELPKEENRMCVGMYGKDVDFFALKGTIETIL
                     VNVGFKGYEIEPQDNNTTFHPGRCAKIVYNNKYVGTLGELHPDVIENYNLGQRVYVAE
                     IDIDFVFDNSDRTKNYVPLPKYPSTSRDIALIVKDDVFVKQIEDIIKENGQGLVESYK
                     LFDVYKGSQIEAGYKSIAYSITYRSKDKTLTDEDVAKVHDKILSELSEKLNANLRSN"
     gene            complement(72099..73118)
                     /gene="pheS"
                     /locus_tag="KOU88_001663"
     CDS             complement(72099..73118)
                     /gene="pheS"
                     /locus_tag="KOU88_001663"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBK3211558.1"
                     /translation="MQEKLLALREAALSEIKEAQSIESVESLRVKYLGKKGEITAILK
                     EMGKLSAEERPVVGKVANEVRENIELSINSKKEEINAIEKERKLKEEVIDVTQPGKVL
                     KVGKKHPITQIIDEVTDIFIGMGFSIAEGPEVETVENNFDALNAPKDHPSRDMSDTFY
                     INDGVLLRTQTSPVQVRTMRSQELPIKVIAPGRCFRSDSPDATHSPMFHQIEGLVVGK
                     DVTMAEFKGTMDIFVEKLFGSDIKTKFRPHNFPFTEPSAEVDVTCFKCGGKGCPMCKY
                     EGWIEILGSGMVHPNVLRNCGIDPEVYSGFAFGVGVERLAMLKYEIDDIRLLFENDMR
                     FLNQF"
     misc_binding    complement(73168..73402)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(73746..74543)
                     /locus_tag="KOU88_001664"
     CDS             complement(73746..74543)
                     /locus_tag="KOU88_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBK3211559.1"
                     /translation="MITNINSKDNEKLKYTRALLKSKNRNKESKFIIEGYRIVMLALE
                     CMANLDYVFINEEFENKKEHVKLLEDLDKKNTKIYKTTNKNFKELVDTENTQGIIGVV
                     SFKKKKLSESINKKDKFVLILDRIQDPGNMGTIIRTADSAGVDAIIALKGCVDIYNPK
                     VIRSTMGSIFDMNIIDASQDETVDMLKSLDFNIVSSYLNTENFYDKIDYGSKVALVIG
                     NEANGINEELVSKSDILVKIPIYGKAESLNAAISSAILMYEIKKYLI"
     gene            complement(74732..75403)
                     /locus_tag="KOU88_001665"
     CDS             complement(74732..75403)
                     /locus_tag="KOU88_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBK3211560.1"
                     /translation="MKQYIVIGCGRFGSSVASTMHLLGHQVMAIDKNEDSVQSISDKV
                     THSLIVDVTDEQALRSLGLGNFDVAVVAIGSDIRASIMATLIAKEMGVELIICKAKDE
                     LQAKVLYKIGADRVVFPERDMGVRVAHNLVSDNILDHIELDPEYSIVEIVTPNSWVGK
                     TLIELELRARYEITVLAIKTGKNINVTPSPDEELTAGSILVIIGQNTSITAITSGNKG
                     IIRRR"
     gene            complement(75714..77090)
                     /locus_tag="KOU88_001666"
     CDS             complement(75714..77090)
                     /locus_tag="KOU88_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HBK3211561.1"
                     /translation="MKTIVRRLILYADGMRPTQIMVSGFAAIIVIGALLLTLPIASQS
                     GESIGLLNALFTATSAVCVTGLVMVDTATYWSLFGQIVIITLIQIGGLGFMTVATMFS
                     LMARKKIQLRERLLIQESLNQADLSGLVRLTRFVLIITITIEGIGALVLSTVFIPQFG
                     LSKGIWYSVFHAISAFCNAGFDLMGSVSGPFTSLNSYVNNFTVSMTVCALIVLGGLGF
                     PVVLDIVRKRRFSKLNVHSKVVLFSTATLIFVGALFIFLIEFNQKATMADLPLKGKVL
                     SAIFQSVTARTAGFNTLDLATLRESSVFVMIILMFIGASPASTGGGIKTTTLAVLIIT
                     VRSFLSGKSDIEAFERRLAPSTIKKSLGIFVISISAVIFGTLIISITQPNFTLVQSAF
                     EVTSALATVGSSLAGTPNLNALGKIIIIIFMFMGRVGSLTLFMAILSGGRRKSQPIRY
                     AEGKIMVG"
     gene            77519..79261
                     /locus_tag="KOU88_001667"
     CDS             77519..79261
                     /locus_tag="KOU88_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloendopeptidase"
                     /protein_id="HBK3211562.1"
                     /translation="MVKSKKKIFVFLILIAVFIIFASYIRNYTNDTKKDSVRGTIPFE
                     KMEYKRPNIQSICENINKCNDKLLTAKTAKEQLNLFNEVDKIYQDFYSTLTIAKIRNN
                     IDSSDEFYSKEYKYLMSKSVDVDMSYKDFQDRFVTSKFSKELEKELGKDTFNYLKNIG
                     KLNSKEVEGLLKKEQDLVVKYEDLLAKSTVSIDGIEVDFEEALSRPNLSPEEYVKIYS
                     DYLKKYNPIFGNIFLELIQTRTEIASKQGFKNYIDYAYMNLNKDYSQEEAKKFRQDVK
                     DYIVPLYREISSKPSDSSIYIKVYKNRSFRKFDKVLEDISPKLKESFDYMKKYDLYDY
                     SSGKNKSPGGYTTYINKYKAPFLFNTWDNSFLGVTSFAHEFGHFYNYYNSINLNNKMQ
                     PSIDVCEVHSTSLEILFYKYFDDFFGKQSEAIKKEHLSIVLNTIIDACLYDEFQEIIY
                     KNPYMSLNDINKLFFDLEEEYGVSNNILREKNAPFWILVSHNFQVPFYYLSYGLASDV
                     SLQIWQLSQEDYRKAVDVYMDFLNQNTDAGFKDVVEKVNLQLPFQDGNLEEISSTLYD
                     YFGIDNPLELKNAS"
BASE COUNT        24849 a        14705 c         8736 g        31070 t
ORIGIN      
        1 ttatttttac tataaaagtt aaatttataa gcttacttgt tataaaaata acttttataa
       61 tttatttcaa aaaaaatatt gatttttgtg tcgcattttg ttataataaa ttaaggttat
      121 ccccctggta accctagtta gttaatatat ctattcccaa taccctttca taaggatata
      181 ttttatattt attaaaaatc ggattagtaa cggaaattaa ttcggtggaa aaaaagagct
      241 taccccgagc tctttttttt tctgcaaaaa atcgtaaaaa taaagttaat attaatataa
      301 ctttaatttt aaaattaata ttaaccatca ctaaaaaagg atgtattgaa tttctaatat
      361 caataacatc ctttttatat aattatagca cttttgctaa aaatgctttt gttctttcat
      421 gttttggatt tccgaaaact tcttctggag tattatcttc aagtatactt cctccatcta
      481 taaaaataac tctatctgca acttccttag caaatcccat ctcatgagtt acaattgcca
      541 ttgtcatacc ttctttagca agttctttta taacatccaa aacttcgttt accatttctg
      601 ggtcaagagc agatgttggc tcatcaaaca acatcatatc tggttccata gcaagtgctc
      661 tagctattgc tattctttgc ttttgtcctc cagataattg tgatggatat gaatcttttt
      721 tatctaaaag accaactcta ctcaacaaaa tttctgcttt tttttctgct tcttccttag
      781 tcatcttttt taatttaatt ggtgctaatg ttatattatc taaaatagtc ttatgtggga
      841 ataaattaaa gttctgaaac accataccta tattttgtct aacctcatca atattagttt
      901 ttttatcgac caaatttttt ccttcaaata ttatttctcc acctgtaggt atttctagta
      961 aattcataca tctaagaagt gtacttttac cagaaccact tggacctact ataaccatta
     1021 tttcgccttt agcgatttct aagtctatat tttttaatac atttaaatct ccaaaagatt
     1081 tacttaaatt ttttattgta atcatattat cactttcctt tttactattc tatgttttcc
     1141 ctaaatgcta aacatgctct catctagtta gacacagata gtttcttttc taataatcca
     1201 actaatcttg atagagtaaa tgttataaca aagtaaattg ctgctgctac tattaatggc
     1261 tctaatgctc taaatgctgc attttttact atatcagcag tacgcattat ctcaacaact
     1321 cctattacag atattattga agattctttt acaagtgtaa taaactcatt tgctaatgaa
     1381 ggtaatatat tttttatagc ttgaggtatt attatatatc tcatagttga ccaataattt
     1441 aatcctaatg atctacttgc ttccatttgt ccattatcaa ctgattgtat acctgatcta
     1501 agtatctctg ccacgtatgc accagagttt actgataatg caaatgcact agctataaat
     1561 tcacttggta taccaaacaa catagggaat cttattccta attgaggtaa accaaaccat
     1621 actatatata tctgtactaa taatggtgtc cctcttaaaa cctcaatata gattgatgat
     1681 attgctctta atactttgct ctttgatatt tttgccatac agataattat acctattata
     1741 aatccaaagc ataatgccac aagagaaatt gatactgtca cacctgttcc ttccaaaaaa
     1801 gaagtcccaa atctacttaa aaaactaaaa tctaaactca taatttcatc tcccacataa
     1861 ctttcttact aatttgaagc agcttcagta gatgcttcat ttaaaaattc ttctatcttc
     1921 ttgccatctt gtaattcttt tatctttttg tttaataatt ctataaaatc tttgttattg
     1981 tcagattttt tgattgctgc tgccatacct tctgttacat ctttcccaac ttcagtattt
     2041 gccattttta ttccatcata ttttttaaca tttattaaag aaactgcttc attagtaaca
     2101 actgcatcta tgtttccatt ttttaattct gtaattaaat caggtattgc tttcaaagat
     2161 tttgtagttg tcatttttaa agtgttaact acatattctt cttggatact tcctgcttga
     2221 actccaactc taagtttctt taaatcatct tcagttttta ctttgtctat atctgcatct
     2281 ttaactataa ctgcatttct acttaaataa tataattctg aaaaatcaac actcttttct
     2341 ctctctggtg ttggagacat gcctgcaaga acaatatcaa cttggtctgc atttaaagca
     2401 cctattaatc catcaaatga catatcctta atttcaacct ttacaccaag ctcttttgca
     2461 aattcttcag ccaacattat atcgaatcct tttattgaat cttttccatc tactacctta
     2521 tgaaattcaa atggaggaaa ttctgcacta gtaccaacaa ctaattttcc attgtctttt
     2581 atttgttcta actttgtttt ttctcctcca ccactacatc ctactagcga taatgtcaat
     2641 cctaatacta atcctaaact taataatttt ttaaatactt tcattttaac tacccctctc
     2701 ttttaattat aatttccctc agattttaat acttaaatgt ttcgagttac aaaaaaagtc
     2761 tctcagtctt taatgactaa gagacgactt taccgcgtta ccactcttat tgataaatac
     2821 ttatattact ttcaaaattt gtgactgtta gcttttaagc tgtatggata tttttatttt
     2881 aaaatcaaaa aagtccctta gctttacagc taagagacga attatatccg cgttaccact
     2941 ctttttgata agtaagtact tatcctctca atcccttaag gcgggtaaac caattatcat
     3001 actaaagttt ctgataatct cctccagagc tctcttcaca tagacttcat tgttaggctt
     3061 acaccaaccc ctaactcgct gtaaatccat atatgctact ttctctatca ttggatttgt
     3121 ttccttaaat tgttaataca attgtacttc cttataatat ttttgtcaat aagtttttta
     3181 tttttttaat aatttttact tgtaaattat ctaaatacta ctgtttatat ttattgatat
     3241 tatttgtgta attataaata gtatatttca tatttttagc tatttcttaa ataatactaa
     3301 ataatatctt tcacattgtt gctttttctt aaacaatact aaataatatc tttcacattg
     3361 ttgcttttct taaattacac taaataatat ctttcacact gttgcttttt ctttaataat
     3421 actaaatagt atctttcaca ctgttgccct ttcttaaaca atactaaata atatctttcg
     3481 cattgttgct tttcttaaat tacactaaat aatatctttc acactgttgc tttttcttta
     3541 ataatactaa atagtatctt tcacactgtt gctttttctt aaattacact aaataatatc
     3601 tttcacattg ttgcttttct ttaataatac taaataatat tttccacatt gttgcttttt
     3661 ctaaacaact ataaataata tattaaaccc ttatttcttt tttctaataa gttaaataat
     3721 acattttaca catatctatt tgtcttgcac ataataaata atacattata tttctatcta
     3781 aatttagatt ctaaattaaa tagtataaat tatattcttc aataaacaag ttttcaaatc
     3841 caagattcgc tctctatctt taaactttat tgtaaacata attccatctt ttttaattat
     3901 ttctccttca tgaaattttt tatggtatac cttatcccct acaccaatac tgtcaatttc
     3961 ttttttcgtt ggagatttta tatcattaat aaataatgat ttatcaactt tcttaccata
     4021 cttatttaaa gtagagctta tacataactt ttcttcagct cttgtaatag caacatacat
     4081 cagtcttctt tcttcttcta attgttcttc ttttttctct tccttacaaa tatcatatga
     4141 tttttcatga ggtattgttc cttcatttac acctataata taaacatttc taaactctaa
     4201 tccttttgca ctatgcatag ttgtaaatat gacaccctca gtctgcttat tcttgttatt
     4261 ttccgttaac tcagtcttta ctctatcaat atgctctaaa aactctgtaa cagtattaaa
     4321 attagttgct gaactctcaa gttcatttaa tatctctaca agtccattag tctttatctt
     4381 tctgttgcta caataatcta aaacatatct atcataatca agactagttc taatataaga
     4441 tattgcattt ttaggattta aagtatttaa ataacttaaa tctatttcca aatcatttat
     4501 tgttttaact tgtttaggat gaagattaca cttatttatt aatgctgtta taaagtcttt
     4561 ttcatcctta accatattta tactgtcttt ggatatatat ctaaaaggct tgtttataat
     4621 tctcaaccaa tctttatttg attttggatt aatacctatt cttaaatagg ctagtatatc
     4681 ttgacttgcc caatggtcat atattgtaat tactgagtct tttactacaa atggaatcct
     4741 catatccata aatacatcta ctaatgctct tgactgtata ttagttctat aaattactgc
     4801 aaaatctgaa tactctacat aatctttttg tatttcgtca attatttccc tggcaatata
     4861 taaggcttct tcctctgaat catgcggaga aatataggta acacttcctc catccccctg
     4921 actacactta atgatttttt catatctatt tttatttttg tcgataagtc tatttgcagt
     4981 atgcactatc tcacttttag acctgtaatt tatatctaat attatttttt tagtattatt
     5041 aaagtattgt tcaaattcaa gcaaaaaatc tggtctagca cctctaaatc catatatact
     5101 ttggtcttca tctccaactg caaatatatt gtttaatggg ctacaaatta actttaaaac
     5161 ttcaaactgt actttattta tatcttgaaa ttcatctatc aatatatatt tatacacatt
     5221 tctaaccatt tctagtgcag acttattgtt caaaagtaaa taataagttc ttataagcat
     5281 atcatcaaaa tctattttat taactttaga tttttgttct tcgtataagt tgtatacttt
     5341 taaaaactca tcttttgtta atacttctga attaaattca tttttatcca taagttcatt
     5401 ttttacatag gaaatttcat ttataacttg tcctatattc tcatcatcat cagcattctc
     5461 tatatttaaa ctttttagga ttgccttgat tgtcattcgc tttgactttt catcaaatat
     5521 actgtctaag ttgtatcttt caaagtatct tagaatttta aaaaatacag agtgaaaagt
     5581 accataggtt accttattaa gtcttatatc atcacttaaa ttcaaagctc tatttttcat
     5641 ttctattgaa gatgccttgg taaaacttat tgccaagatt cttgttggtg ctatgttttt
     5701 gtttacaacc atattggcta ttctatatgt aattactctg gtcttacctg aaccaggccc
     5761 tgcaagtatc atgcaaggcc catctatatg ctcaactgct tctaattgat tttcatttaa
     5821 ctttcttata tctatatttg ttgtgattat tagctccacc accttgattt ataattatat
     5881 tattttcttt ttaattataa actaaaagtt cataaaaata aatttaattt ttcctctatt
     5941 aaaccacatc attcctattt tcatgacata tcttgagttc ttttttaatt ttgtcgctta
     6001 tatcttcagg tataaatgat ggtttactaa tatagtagcc ttgcatataa tctactccaa
     6061 gattaattag tgtttccatt tcaccttttg tttctacacc ttctgctatc actttaatat
     6121 ttctttcgtt agaatatgag ataagatttt ttaatatttt ctgtctgttt tcatctttat
     6181 caatacctct tacaatagac atatcaatct ttacatagtc tggcattata tataatagta
     6241 cagcatctcc gttgtaacct gtcccaaagt catctaaagc aatttctata ttccaatggt
     6301 ctatatatgc tttctttttc tcaataaaat cttcattaat cttatcattc tctgttattt
     6361 ctagtactac tctatttaaa tattcaccat ataaatcttc aatttcctca aaatctactt
     6421 ttgacaaatt attattagga atagaattta agaacagttt gcaatcgcca aatttttctt
     6481 tgtatttttt aaatgattta agtgctttaa accatgtaat acgctcaatt tgatataatt
     6541 tagactgtga acgagctaat ctaatgacat ctattggtga actaaaagtt tttattttag
     6601 gtctcataag tgcttcatat gcaaaaactt tacctttaca atctacaata ggctgaaatg
     6661 catactcaac taattgacca tcaattaact tgtttaattc ttctctatta ctcaataaga
     6721 atgaatcctt attatatata ttaatatcaa attcactaac ttcacccttg attgtatttt
     6781 taatttgata catagcaaaa tctgcgtatc tcattaattc atcatagttg gttgaatcat
     6841 cagggtacca ggaaattcct gctgatgccc ttattttaaa ttctgttcca tcatgaagtt
     6901 ttaataaggt attattcatc tgtttcttaa cagaattaat aatatctctt atactatctt
     6961 tactttcata tccatatata aatacataaa actcatcacc tgaaagtcta gatactatac
     7021 cattccatga tataaacttc ttaagtatgt ctgcagcaca cctaatatat tcatcaccag
     7081 catcatgtcc atatgtatca ttaatatatt ttagattatc taaatcccac ataataaatg
     7141 ctgctatctt aagttcatct ttattcttaa atttttcttg tatctgtgaa tgaaaagctc
     7201 tcctatttaa aagattcgtt aaaatatcaa aatctctttc atattctatc tttcttttct
     7261 caataaattc ttttgttaca tcaacaacaa caccaagaac ctttagctca tcttcaaaga
     7321 tattcattct tatccactta agttttttat ctttagattc aaacttatat atatatgtat
     7381 tttctgtttc ataactttct tgcaaatatt tatctagtcc ccttaatttt ttcaggaact
     7441 tatttttttc catatatcca tattcttcaa atttgatttc agtagtaaac acgctaaaaa
     7501 attcttttgt acaaaaaaca ttttctgcgt ttttgtataa ctcaaaagcc ccaattggca
     7561 tatctaccat ttcaataatc tgtgataatt ttgacgaaga atctgcaaca tttgcactga
     7621 gcaactctat agctgaagat aattcatcta tttcagatat atttatctta tcaagattta
     7681 ctggttttga tggattactg tttctaactt tgttggctaa aagaacaatt ggttttgtaa
     7741 ataatcttga tgcaatgtaa atacctatta gacctattaa taaagaaatt gctatagata
     7801 ttataactaa tttctctacc ctttttgaaa atgacaaaag acttttttct tcaataatac
     7861 ccaaaagagc ccaacgttca ttttcaaatg gagtattgga gttatataaa tctaagtatt
     7921 gtacactagc ataaatgttg ccattaccac attcattatc tttattttta atcttatata
     7981 tatttttata cgattccttc tgctctaaat tagaatgtaa accatcccaa aatttttctt
     8041 ttaatgagta tccatttgaa attacatttt caaaggccat atcattattt ctatctacac
     8101 ctaaaatata attacccttt ttattcccat ttatctctga atatggaagt aattctctta
     8161 aataatttac acttaaatct attccaagta ctccatatac agttccatct tcataaataa
     8221 ggggaactgt atatgtcata agcctatcac ctgcatttgt caataaaaac ttacttcccc
     8281 agtatcctaa attagaactt gatacatttg gattatcaat tgcagctcta aatggtttat
     8341 aaaaaaaatc atctccatct tgctcatttt cacttttaaa tgaaaactta ggttcccagt
     8401 aactgtccat agatattcca aaacttcttg ctatgtctga tgaacctctc tcaattaaca
     8461 aatcagaatt atcatttgga ttaaacttag ggtctaaatc ccttatatac aatcctgtcc
     8521 tacttatttc acctttacta tctattgact tatcgttaat atttttgtca cttaggatta
     8581 taaaagctcc tgtaacagaa ttttttctca aaagatatat taaatcattt gatatgcttt
     8641 ttataatatc tttgttaatt tcttcattgt tgcctacatc ctcaattaag gcattttttt
     8701 catttaatac tttttttaca gaggaattaa ttgtagcttc cgtttcactt gtatttgacc
     8761 atctttgtaa catttcattt tgtatataat ttttacgatt aattactctt tcatttaaga
     8821 tgtcaaacga attatcattt aatttcttaa tagttcctcc ccataaaatt gtggcacaaa
     8881 ataaacttgt ttgaattagc ataacaataa ttaggggaaa tatcatcttt ttcattattg
     8941 aattgttttt tcttagattg ttttccatac ccattccacc tatacctttg tgctcgtcaa
     9001 cacactaact gccaattcat ctattttttt atagcatttt caagctcagc cttaaaactt
     9061 tcaaaccaag ttttaaaatt tttatcatta ttaaattgtg ctactgcatc cttcttagaa
     9121 gttccacttt ttactaattc atttatttta tttgaatctt ctttagcttt atcaagcatt
     9181 gaatattcaa gtatttgtct agctttagtt ccaccatcaa atgctttatt agtatataaa
     9241 ttacaactgt taatctgttc aatagatgag gctattgaac cttcaacttt atcagataaa
     9301 ctcaaattat ctttcttcat aacttctttt ataacatcca aatcattcgt ttttttcttt
     9361 actggtaagt atccagaagc aatagagaat tttatattag gttctttatc tgtaaaccat
     9421 tttaaaaatt ctactgatgc atattcttct tctttagtag attttgttac agccattcct
     9481 gcaccttgtt gtacagcata ttttccttct cctttaaaac gtggtgcttg aaaaacagat
     9541 gtttcaatat tataactctc attatcattt agcattactc tatctggaaa gtatgctgct
     9601 cctgaactag aacctacaag agctaatata tcacctgttt ttgcatcatc agaacgaaac
     9661 ttaccataag aagcaaaata tccatttata tatggtacat agaaattatc ccatagtttt
     9721 ttcataactt tttcatcaat atttagtgta actttaccat ctttaacaga aaaaatttct
     9781 actcctagtt gtttacttcc tataataata taatttgcta aagcatctct tccaaaaaat
     9841 gctttaccat cattaggctc tttcgttaaa ctatctgtcc attcataata tttttttgat
     9901 gtctctacta atccttcaat tgtttttata tcatttatat ttgaatttgt agcttttgca
     9961 aatttatccc aatcagtttt atttaacatc aaaatttcag ttgattttgc aattgggaaa
    10021 agtttaaact catccttaga atttattctg ccttcttcta catattcgtc tatgtattca
    10081 tttaattctt ctttacttat gtacttatcc atatctacta gtaaccctaa tttatccatt
    10141 tcatatgcag tatctgagta tgctgcaaat atatttggta catcttcaga accaactttt
    10201 ttatttgcag aatctaaaac tttctctgat aaatcaacta cattaccttg actgaatgct
    10261 tcaacaataa ttcctttttc agcacctaca gtgtcattaa attccttaac aagcttatca
    10321 aaagccattt tctgctgtcc attataataa tgccaaattt gtattgatgt cggattttct
    10381 gggtctaact tataattatc ttccttcttt aaactacatc ctgtaagtaa taaaacaatc
    10441 attgatgtga taattaattt tgcaaactta cacctattca taaaatctac tccttcaaat
    10501 tataaaattt ataatagcat taaaactgta acttcactat ttatattaat tatagaacgt
    10561 ttattgatat atttaaacag gatttacaac atatttaaaa gcaattaaga aacatactat
    10621 tacaaatata gaaaataaag cttttacata atttttattt ctaaatgcac caaatgacac
    10681 caatccttgt tgaatagcta ctgtaattac taaaagtatc attattatat taagttgaac
    10741 cagtttaaat aagtaaagta atgaaaacac tactaaaagt acacataata caatactaga
    10801 tttattaata atatcatcaa tcttatctac cttcttagat tgcttattaa ctttatttaa
    10861 tttttcttta tttaaattct caactttttt attatacctt tctcttgttt tatctttata
    10921 tttagtattt ttatttccca tttattttcc atcctctata aattttttaa ttgagcttat
    10981 acattattta aatattatat atttaagata ccatatattc ctacaaaaag gtaacttact
    11041 atgtatctat ttttgatttt cgcataaaaa agccatctcc tttagaatta attctgtatt
    11101 gagacagcta atttaactat ttatcctttg aaacattttc tacattatca tatttactat
    11161 caactaaaac tatatcaact cttctatttt ttgacctacc ttcttcagat gaattttctg
    11221 ctattggtct aaactcacca tatcctacag cagataattt atctggtgct atacctgcat
    11281 tgtcaataag aagttgaaca acattggttg ctctcataac tgataaatcc caatttgact
    11341 taaactctga attttttata gacatattgt ctgtatggcc ttctactctc atgtaactat
    11401 tcatttcatt taacatctta cctatttgaa taatcttatc tctagaatta tccttcacaa
    11461 tcgctttccc tgtatcaaat agtattgtat ctttaaggct tattactaat cctctatctt
    11521 gaactcttaa tgatactgaa ttagccatac cattttcgtt taaatacttc tggatttctt
    11581 caccaatttt tttaaactta gcattttgta aagtatctaa atcattactt cctgcttcaa
    11641 ctactggttc tatcttgcta ttaccacctt caataactcc agaagaacca ccaaaagcag
    11701 aatttagaga ttgagataat tgtttatatt tctccgcatc aacattactc atagaataca
    11761 ttattacaaa gaaaatcata agtaatgtta tgaggtctga ataagttaaa agccatcgct
    11821 cattgttttc ttctttttca tcttcatcat acaacataaa cattccatcc ttttatatta
    11881 ttcagctcta ccaccaattt cttcaagttc aattagttct tttgaattta aaaatatttt
    11941 taatttttct gtcattaaat tagaattatc accctcaagt atggataata ttgcttctat
    12001 caccaaaagt ctttcactta cttcttgttg atttatagcc ttaagttttg atgctattgg
    12061 taaccatatt aaattggcag aaccaacacc atacaaagta gccaaaaatg caacagaaat
    12121 ttgaggtcct aatgcatctg gattacttga aagattacct aaaatatgta ctaatcccat
    12181 aactgtacct attatcccca gtgtaggtgc atatccacct gctgaatcaa aaattgctat
    12241 tccttcttta tgtcgttttg atgttatctg tatctgtgat tccaatatat ttcttatagt
    12301 aactgcatcc actccatcta ccataagttc aagccctttt ctaataaaag ggtctaattc
    12361 atcattctca cttatttctt tgtcaatact aagaagcccc tctttcctag cctttgttgc
    12421 aatttctttg aaatagatta tattttctat gttattaggc tttttatttt taaaagctaa
    12481 taacattatc tttatagact ttttaaacac agggaatgga gtcgaagctc caacagctcc
    12541 tatagttcca ccaaacacaa caagtgctga tgaaaataca aataatgctc caacatgtcc
    12601 cccatcaata acaaaagcaa ctaccaaaga tgctatcccc actatgaaaa aaattaaagt
    12661 tgtcatctat tccctccttt ctttagttat acatatctaa tcatttatga cattataaaa
    12721 agactatctt taataaaaat agcctttaat aattggcgga gaaggaggga ttcgaaccct
    12781 cgcaccggtt acccagccta atcccttagc aggggatcct cttgagccac ttgagtactt
    12841 ctccatatct ctatactagt aaattatata ataaaatcat attttagtca attgttttat
    12901 aaaatttgag ttattttgaa ttattaaaca tctattttta cttttttgct taaatgtaag
    12961 ttttaaatat ggtaaaatta tcttgcataa cacttataat attatttgat aaatatacat
    13021 acattaacaa atatacctaa actctgactt aattgtaagt tatgccaaaa ctaaaataat
    13081 actagtccaa ggaggatatt ttatgttacc acaggaaaga tatgagaaga ttttaagtat
    13141 tctcaaatca gataatataa ttaaaataaa tgacatagtt caaatgtttg atatatcaat
    13201 agaaactgca cgaagagatt tagcccatat ggagagtatc ggtcttttaa aaagagttta
    13261 tggtggtgct ataccagtta tagcaagtag cgtagaactt aactatgtta aaagaaaaaa
    13321 aataaactca aacgacaaaa aacagattgc tattaaatgt agtgagttta taaatacaaa
    13381 tgatactatt tttatggata ctggaactac tgtacttgaa gtttcaaaaa atttgaaaga
    13441 taaaaagaat ctaactgtaa taaccaactc aattttagtt gcaaacgaac ttatgaatac
    13501 taatataaaa gtatatgtgc ttgggggcta tcttagagaa actgaaggtt ctttttctgg
    13561 tccgcttaca ctgtcagcta ttgaacaatt taatgttgat aaagctattt taggcgctgg
    13621 aggtatcact cttgaaaatg gaatctctga ctatcactta gaagaagcac ttgttagaaa
    13681 aaaaatgatt gaaaggtcta gaaaatctat agtagttgtc gaacctccta agtttggtat
    13741 aaattcattt gcatcagtag ctcctataga acatatagat actattatta cctctgctag
    13801 tatagaccat aatataataa tagagttttc tcaaaaagga atacctttag tcatagctga
    13861 taattagctt atatgattga tttttagttc cttgatgtaa taaattaaaa ttaaggagcc
    13921 aaataattat ttatttagct ccatttatgt ctaaactata ctttatattt taattatgta
    13981 actactttca gttagcttat catttttagt tatttgattg ccattttatt taatttataa
    14041 gttttagtta ttcgattatt ttttaattgt ctgtcttttt aatttatttt tagttattta
    14101 aactcctatt ttaaaataat ttaaatttga cttaagtatt gtttattcta cactgcatct
    14161 ttcttcattt taatactttg ttcttcttcc aaggttaaat cttttgtcat aagtatagca
    14221 agtgcaattg ccaatactcc tccaaccaat tttccaatta caacaggtgt aatcatctct
    14281 ggaactactc ctgctgtaaa tcctaaatgg tcccccaaag ctgctgtagc acaaaccagc
    14341 caagcagtat ttactacttt cccctttgga ctcatatctt tcatcatttt atatactgga
    14401 atactattgg ctaaagtaaa aactaatcct gctgcactag tggcatccat acctaatttt
    14461 ccacccacta ttgtaagtgg tttattaaga actttaacta ataaatgtaa tattggaaaa
    14521 gtacctaata acacgattgc aatacttcca attacttgaa taccttctct tataggtgtc
    14581 atgcctttta taagtactat acctgttatt tcttgaaatg ctgctgctcc caaacctatc
    14641 gttatcaata tagatataaa ttttccaaaa actaatgacc catttatcat aagcgtagaa
    14701 ttaaatttta aacctactgc caatattact gccaatatta tcactggtat catatttata
    14761 attaccattg ataagttaaa tcctgctatt aatcctccta taatacctcc aaaaggtatt
    14821 gttatcaagc ctatcagtaa cccttttgca aagaatggtc tgtcttcata ttctataaga
    14881 cctagtccta ctggaattga aaatactaat gtacatccaa gcatggatga cacaaccaat
    14941 cctgcaagca ttcctgcctc tttattgtgt gcaagttcca tagccaatgg ataccctccc
    15001 atatcattcg ctaaaatagt tgcaaacata gatgggtcag ctccacagag attgaagatt
    15061 ggtattatta taggacctag tacatctgaa attactggag ctaaacaaac tataccaacc
    15121 attcctaaag ccaatggacc cattgaatta aacccttctt caaactgctc accaagtcca
    15181 aatttatttc caattattct atctaacgct cctaaaagca ctcccacagc cattatgtat
    15241 aatataattt tatcaaaggg catttttaat tcctcctata catgtaaaat actctattgt
    15301 aacttaatta gcacacacct ttttggtatc gttttcccaa ttcatagctc tttttactgc
    15361 ttggttccat ccaagtaata tttcttctct tttttgagta gtcatatttg gaatatattt
    15421 tttgcttatt gtaaattcac ttctaatttc atcaatactg ttccagacac cacaagaaag
    15481 acctgccata tatcctactc caagtactgt cgtctcagga ttttctgcaa tttcaattgg
    15541 tatacctaat atgtcggatt gaaattgcat tgtaaagtta tttttagtaa ttccaccatc
    15601 tactctcaac atttttattt ttttccctga ggctaagttc atagaatcaa caacatcttt
    15661 gacttgaagt gcaacagact caagagtcgc tcttactata tgctcttttt tagtacttcc
    15721 tgttatccca accattgtac ctctagcata ttggtcccaa taaggtgctg ctatacctgc
    15781 aaatgctggt acaaaatata cacctccagt acttgatatg gaatttgcca tgtcatcagt
    15841 ttctgaataa ttttttataa ctccaatgcc atctctaagc cattgtattg cagcacctgc
    15901 tatatacact ccaccatcat aagcatatgt aaccttatct cctattttcc aagcaacagt
    15961 tgtcaaaata ccattacctg ctatatttag ttcctcacct atattcatat ataggaaaca
    16021 tcctgtacca taagtatttt taaccattcc tggttcaaaa catccattgc caaataaagc
    16081 tgctggttgg tctaccattg aagcagtaat ttttatagaa accccacaaa atgcctcctt
    16141 atctgtagtt ccaaaatcac cactcgtagg cattatatct gctaaaatac ttctaggtac
    16201 tcctataatg tcaagcaact ctctatccca atccatatct cttatattaa aaagcattgt
    16261 tcttgctgct gtagatacat cagttaaaaa agattttcct cctgtcattt tccatattaa
    16321 ccaactatct aatgttcctg caagtacttc tccattttta attttttctt ttacaccttt
    16381 tacattatct attacccatt taatttttgt acctgagaaa tatgggtcta taattaaccc
    16441 agtcttatct attatcttat tttctaaacc tggtatattc tttaaatttt ccacataatc
    16501 ataagttctc ctgcactgcc acacaatagc attgtaaagt ggtttacctg tatttttatc
    16561 ccataacatt actgtttcac cttgattatc tataccaatt ccttttatat cactttcatt
    16621 gattccattt tcaaaagcct gttgtaatac attattactc acagtttttg tattattcca
    16681 aatttctata gggtcatgtt caacatatcc agattgtgga tatatttgag tatgttccat
    16741 ataatcgcta aaaacaaact ctgatttttc gtttatcaat actgctcttg ttcctgttgt
    16801 tccttggtca attgctaata catatttcac tttaaatgtc cccctttatt ttcagaatta
    16861 ataaattctt ttttattttt tgaatatata atctattcaa gttatttata ttttatatca
    16921 tcatgtggat ttatgcaata ttcattacaa tattttttgt tatttttaat tatagtgatt
    16981 aaaaaagtat ttttattgaa atgttattgc aatatttatt attttattct ataatctagt
    17041 taaaataaca cataacattt taatatttac acataatcag tcattcaaaa atttaaattt
    17101 aactttttaa ggaggcttta caatgaaaaa aacatatcta ttcagtcctg gaccagtaat
    17161 ggttacagat aaagtcagaa attcacttct tcactatgat atatgccata gaggaaatga
    17221 gtttatggat ttattcaaag atacacaaca aaaaatcaat aaactatata atgcaacttc
    17281 taattactac tcattaattg tatctggctc tggaacatct gtaaatgaat gtgtactatc
    17341 ttctatcttt gacaaagaag atgcagttct gctagttagt aatggtgttt ttggagaaag
    17401 gctagaagaa atattatcta cttataatgt aaaaacatat aaacctaatt ttgaatgggc
    17461 agaatacccg gacctagaca ttttagaaaa atacataatt gaaaattctg atataaaagt
    17521 aattgctatg gtgttccatg aaactagttc aggaatgata aatccagtcc ctgaactagg
    17581 aaaacttgct aagaagtata acaaaatatt ttttgtagat gcaataagtg cctcagcagg
    17641 tgaatatatt gatgtggaag agtttaatat agatataata acaggtgttg gtggcaaagc
    17701 tcttggagca tttccaggtt ctgcatacct ttgtgctaaa gagagtattt tacaaaatat
    17761 taaagaaaat caatgtaaga atgtgtatct taatctttat aaacactata aagttgctaa
    17821 atcatcttct caaacaccaa atacacctaa tgttacttta atatttgccc ttaatgaagc
    17881 tttaactgag tttttggaag atgacagtaa aatagaaaga tacaaagaat gttctgctat
    17941 tttaaggaat ggtatggaag aattgggtct aacattttta cttccagata agtatatgtc
    18001 taatacagta acatctgtat ttctacctaa agaaatcaat gtaaatgagt ttatattagg
    18061 gctagaaagg gaaagtggct atgttgtcta tccaggaaaa ggcaaattcc tagatgctaa
    18121 catattccaa gtagcaaata tgggagaaat atatccagaa gattgttata aattcttaga
    18181 tatcttaaaa tcaaaattgg agataaaaaa agttatataa cagtttgttt gtaaaaccct
    18241 acaatatatc agtataaatt aaatagactg atttttttaa attttcctat aataaattat
    18301 attttatatt tttgtataag ggtgaactat aatatgtaaa gttcacccct atttcaaatc
    18361 tttttccttc agtataatct ttttctttta atttatttta tatttttgac ataattattc
    18421 ttacatttaa ttgtttttta tttttaacac aatcgttttt tgttaaatca ttttatattc
    18481 ttgatacaat cattcttaca ttctattatt gtttattttt gacgcaatcg ttttttgttg
    18541 aatcatttta tattcttgat acaatcattc ttacacttaa ttattttttg tttttgacac
    18601 aatcgttttt tattcagtca tttaatattt tcaacacaat cattcttaca ttctattatt
    18661 gtttgttttt gatacaactg tttttattca gtcatttaat attcttgaca caattattct
    18721 tacattctat tattgtttat ttttgacgca atcgtttttt attcagtcat ttaatacttt
    18781 cgacacaatc atttttacat tctattattg tttgttttga tacaactgtt tttattcagt
    18841 cattttatat tttcgacata attattctta cattctatta ttgtttattt ttgacgcaat
    18901 cgttttttat tcagtcattt tatattttcg acacaatcat tcttacattc tattattgtt
    18961 tgttttgata caactgtttt tattcagtca tttaatattc tcaacacaat taccttttca
    19021 ttcaatcaaa gtaatcttta agcattattt ttcaagctca tcaaagtaat tatatacgat
    19081 aacctcacct gtctctttat ctgtagtctt tataatgccc ttagctccat ttacctcttc
    19141 ttttgtaaat tcatcatcta gcacaacttt gaatttatct tcctttccat aaccttgttg
    19201 aaattcatct ctcaaaattg catttttttc tgcttttggc ttcaactcaa attcaattcc
    19261 agatttcatt tcatcaaaat aatttaatac tacaacctca ttattcattt tattagttgt
    19321 ctttataatc cctttagctc catttacttc ttcttttgta aattcatcat tcaatgttat
    19381 attaaatttg tcttcttttc catattcctc ttgaaaatcc ctcttcattt cattgtattt
    19441 agtttcaaac tctttactct tgtttaattc catagctgat acatttgtca atgatgctcc
    19501 aattgccatt actgttaatg ccattactat accactttta aattttttta ctttcatatc
    19561 ttacctccta aattaaatgt tctcaatgaa attatataaa gaaaatccta agttttacag
    19621 tttcattctt gtaactaaaa ttactattat gtaaccaaac tttttgcttc aactattcct
    19681 taaaagttgc ttttttgagg aatagttgaa gttaaataat tagattttat ctatatttat
    19741 agatttaaaa tctaatttat ccatataaat aaatacttat ttttgcaaaa taaaaatttt
    19801 taattactcc aatccttctt atttacttaa aatcctatga taagaaattt aaaagtcttt
    19861 accttcttta acaataattt atttactttt aacatacaaa atatagagag tatatcaaaa
    19921 tcattttact gaatattcta aaaataagta ccccctatta gtatatatat ttacatatta
    19981 aaaaaaagtt ttaaataaag ttatattttt tacaacagtt ttgtaattaa aaacatattg
    20041 aaggtaaatt taaaggtact atatactata aatatgtcga cacaataaat ttaaaaagga
    20101 gaactaaata tgaaaaaaag attaataata atgatattgt ctgttgtctt agtactatca
    20161 agtatactta cgatatttgc atattcaaat attaagtata ataataataa attgatatat
    20221 tctaatatga tagataaaaa aactcaaaat agtgtaaagg aaatcctaaa agaaaataaa
    20281 attaatgaaa aagatataga tacatttatt aaagcagtca acaattataa taaattgcaa
    20341 gttaaaatac ttcaaaataa tataaatata tctaaatctg gatattcttc aatcaatgca
    20401 aaacaagttc catataacct agaaaaattg caagataatt gggtgaaaaa attccctgat
    20461 tatatggatg taaattgtag aataactgct tttagacttt ttaaagattt tataaattca
    20521 aataagaaat ttactggaga ctctattgat ttgaatgtcg acttggacac tataatgaat
    20581 aataaagatg ctaaatttag caccaaagat gtagaaaaat ttatcaactt cttttctgca
    20641 ataccagcta aagatacaga tgatacaatc aaaattgcag aacaaataaa aaatgaatgg
    20701 aaaaaaagaa aaatatcttt taaaaataat aaaaatatat ctattataaa tggatttctt
    20761 cgttatccag aaactaaaaa tgtatttata ggtcatacag gcatatgtat taaaactaaa
    20821 aatggcattc tatttttaga aaaatatggt gttacatcac cttatcaagt tactaaattt
    20881 aaaaataaag aagatgtaaa aaattatatg tttaatagat tgaagatctc agaaggtgaa
    20941 attgaattac ctgaccctat aataatggaa aacgataaac ttatgaaata ataactttaa
    21001 acgcaaaata gtatttataa ttactaagtc aatataatag agaaggtcta tagatttgtg
    21061 taaatacaag cttatctaca atcttatata agaatgttta tataaataag atagattaat
    21121 tctaagtcct attattctat tgaattttat tattatttta tttagattct attgttattt
    21181 tacttagaac ttattattat tttgtttaag ttctattact attttcaatc atataaattt
    21241 acaaaagact gtacataaat ttattttata caaacttatc tacagtcttt tgtgtgaata
    21301 tatctaaata atatcgtatt tatttatttc ctctgcacag tgagaatcag aacctaaaac
    21361 taatggaata tcgtattttt ttaccaagtc taataagtat ccatctatat aaggctcttt
    21421 gcagtactct tttctatttc cagaaacatt ataatcaagt tcataacctt tttctttaat
    21481 taactttatt aactcttcaa gaattttatt tcctttataa tcgtatggaa atacctgatt
    21541 aaactttcta actaaattta aatgacctat tctttttggt ttatgtatac ctaaatctga
    21601 atttacagct tttatcaatg tttcataata cttattataa acagcttcaa tacttcctaa
    21661 tttgtcgatt aaattttgaa actcctctac actgtaatct acacaataat aatcatcatc
    21721 aatcttaatt atatgtactg ataaaagaga atcctctaat tcttctccat atttatttaa
    21781 attctccttt atcccttctt cgtatccttc tataaaatcc acttccgacc caacatttat
    21841 cttgatttta ccctcatact tttctttcaa cttcttgaca tcattaaaat actttggtaa
    21901 atcttcaata ctcatacaac tatcattttc aggagcaggg tctctaaatc catttgcata
    21961 cggaaaatgt tctgtaaatg tcatttctgt tattccaaca tccattgctc tttgtacata
    22021 tttttcaaaa tcatccttac ttccatgagg acaataaggt gaatgtatat gaccatcttt
    22081 cataaataat tcactccttt tttaaagaaa aaatctaata taaatgcata aatcttttaa
    22141 cttcaaaata atatttttaa tcatgctaat ttttattata tctaatatta gagtaatttt
    22201 aaactgcctt ttaagtatct tatcattagt actattttca acttaacatt aatattattt
    22261 tttaacttaa cattaatact atctttaaat agtaatactc aatatataat tacttaacat
    22321 aaaataactc aaattgcttg atgaggcttt tgcagtattt aaagaatata taattattta
    22381 acattaaatt atccaatctt gtaataaaat ttactcatta aagtatatta cagaaaatac
    22441 ctcaaaataa actttttagt tcatgagata ctctttttta catgaaatta gatatatttt
    22501 tatcatttaa acaatgaaag ggagcttata tccatcttta gacaacccct tatataaaat
    22561 ttttaataat taaacatcac aaaatataaa aatcgcttat atcaaacgta taagcgatta
    22621 attatattta catatgtttt ttagcctcta acaacatttt attagcttct tccatatact
    22681 ctatagcctt ttcaatactc tttgctgttt cttcttttcc aatagctcta gccttttcaa
    22741 cccactctct aaatccttct tcatgagttt cattgtgatt tatccaatgt actaaaagta
    22801 tttttaaagt tttttcatcc ttagactctg atgattcctc atgactatgt tcgtggtcgt
    22861 ggtcgtgagc atggtcatgt ggatgttcat gacatatatc tccatgagta tgttcgtggc
    22921 agtggtcatg gtcatgatgt ccatgatgat atcttacaat ctctttatca aaaatcatta
    22981 gttattcccc ctgttatttt atattaaact ctttttttat aaggtttaca gaatctttta
    23041 caagtagtgc taatggttta ccttctaatc caactaactc cacattttct ggcataatag
    23101 gtaaaagtat cttaagtgcc tcactgtctg caatagcttc acttatatta caagtaactt
    23161 ctcccatcat agaattaggt attattacag aaataggtgc aactattata tttgcttttt
    23221 tagctgatac tactatagca ttttcccctg tagctccttt attagcatga gctttcatca
    23281 tagaactagt tgctatagaa ttagtcccta gtgcataaat ttctacatat gtaggtaact
    23341 cttctctcaa agaagaaact atctgggctc caatacctcc acccattcca tctatcactg
    23401 ctattatcat atgaaattcc cctattaatt aattttcttg tattattatc ttatggtcca
    23461 tcaatcttat ttctttaatt atcccatcta ttatcttttg ctctcctaat aaatccgtta
    23521 aataaatctt tccatcacaa gggtctatat taaccacatt ttccataacc ttttctaact
    23581 cattattact tttacaaatg aaagctgatg attcacacat ataaatctcc tcctaatatg
    23641 atttttatta aaaatcaaaa aaagattccc ttaggtattt caatacacca aagaaacctt
    23701 catgatttca gtttttgtat attattatac cttaagtata tcactttaat ttatgtaaag
    23761 tcaattaaag ttaacgcttt ttattatact cttcattctt gtatttttca tatagttctt
    23821 taactaattg cttctcataa tcagtcaaat cgccctccac aaactcaaca ttaaattgtt
    23881 cagctaatcc ctttactatg tttttctgta gaatatctat gtctattttt ctgccaattt
    23941 cattttctat tccacttgct tttttagctg taaatttcat agctctttct ttcaattctg
    24001 gtgtcttagt ttttattaat ttaaacaatt tttctacatc aaaatccagt attattgaac
    24061 catgttgtaa taaaacacca tcttttctgc tttgagcact tccaattacc ttcttattat
    24121 taatagtaac ttcatatgat gcatgtgcat taaaacatgc agctgataaa ttttccctac
    24181 ttattctctc gcctctattt aaattatctg tttctatacc acttagattc aatcctttaa
    24241 ctagaccttc acttatatat ctataagata ggttgatgct cttatcgatt aaaggattat
    24301 cttctcctat aattatacta taggttagct cattatcatg taatacagct cttccacctg
    24361 taattcttct agtatagtct atattcatac atctacactt atctaaatct atctcatctt
    24421 ccaatttctg aaaatatcct atactcaaac aagctggttc ccatgtataa aatctaagag
    24481 ttggcttatt atgtcctttc ttatatgcag taaatatagc ttcgtcaatt gccatattca
    24541 ttgctccttc atatgattta ttatgtataa ctctccactg attcatgatt attacgcccc
    24601 catttttagt ataaatatat cctagaaatc ctctatagat ttatttctct tattgctaaa
    24661 tctatctcac tttgatttaa aggtcttgaa tagttgtata tagtacttcc tggtctttca
    24721 ttatagtatg gtctattaca atccttacaa cctcttattt caaaaggata gcctttgttt
    24781 atgtctttta aaatatcatt gtcaagcttt atactattta agtatccatt tttaaactta
    24841 aaatactctt ttggataacc tttatttatc atataagaca ttaactgtac ccttctataa
    24901 ctttctatgc ttggttgact tatcttttcc attttagttc ctctaactgg agtaaatgca
    24961 aataaactaa tcattacatc attttccttt aaataagtat ataaattgta tatatcttca
    25021 tgactttcac ccataccaac tattatatgt gtacttattt tattgggata tgattttgac
    25081 atttcagtta taaattttaa cttttcatca tagttatttc cttttatttt ttcatatagt
    25141 tctttatttg ctgcatctat tgctattcct attttatcaa ctcctactga aaaaaacttc
    25201 tttatctgtt catcattttc taattttgca gatagtgaaa ttggcatgtc tatcttacca
    25261 cttatatagt ttataaagtc taaaacagag ttatgtgctt cttcacttgc cattgattga
    25321 atacatattc tctttatatt ttttccttta taagctttta aagcatctaa tatttcttct
    25381 tttgaaaact ctggccaaat tactcttgat aatttatctt ttctagtact actttctatt
    25441 gattgagaac aaaaactgca tttatttatg catttttctc caatcattat atatgctgtg
    25501 gtaggaggta tatcgctttt tttgtttaat atcccaagtt ctattgctgt cccaactgat
    25561 agtctaatca taaaacgcaa cactccttac actcatttat tgtcatattc atttctatag
    25621 ccttattctt tgcagacctt gatggtaata ctattctatt gactccacac attatagata
    25681 attggtctag ctcttttcta tacactcctc ttggtctcat acaacctaga ttaatttcag
    25741 tatctggtaa attaattcta gcttcacata aaatatctgc taccccttct aactcaggag
    25801 gttctacatt ttcatactca gttccttttg ttggaataag gactataaat gtaagcttat
    25861 taggaggatt tttctgtagg tattctataa tttcatattc accctttatt tgtcctcctt
    25921 ttaaaccaat acatatatgt ggtgctactt ctgtatgttc ttgtattgta ttatagactt
    25981 caatataatc ttctttactc tttttcatct tataaacttc tcttattgtc tcatcatcaa
    26041 acactaaatc aaaagaaact atatctaaat acttacacaa ctctacaatg ctatctttat
    26101 ccataagacc taaatgagca ttcaatctat atccttgctc ttttaagttt ttaatggtat
    26161 taatatgagt atttataggg acatctccct cataactaca accgccactc aatagaaagc
    26221 tagttatatt ccttgattgt actttttcct catattcttc tattggcacc atattgttta
    26281 agtagtgacc gttgcaatgg gcacatttca aactacattg attgcttgta gtactaagag
    26341 ctagtgtctg gttaggataa gcaaactcta ttttatttcc aaaattcttt aatttaatat
    26401 caaatgctat tttcattttt tcagatagat tcttattcat agtttattcc ttcttaagta
    26461 cattttactc ttctagtaat ttctttgctg ttgggaactg ctctatattc gtatgtggta
    26521 agaaacatgc agaaataaat tcatccatat aacttggata tacactaagt tcaacataag
    26581 ttatttgatt acctatttct tcaagtttat tttttgcatc tttacttata agagctaagt
    26641 aagaaccaac aagtgaacta ttccctatat aagtaaattt ttctctatca atatcaggaa
    26701 gtaaccctat aattattgag ttttctatgt ctaggttgtt tcctatacca cctgctatat
    26761 aaaccctatc taatatacta aaatccatac ctaaactatc tacaagagtg tatgcgcctg
    26821 aatatatagc tcctttagct cttatgaaat tatctatatc aacttcattg actactatat
    26881 cattttctaa atcaaattct tctttaaatg ctaatacata ctctcctatc tcatgctcat
    26941 taaatctaac tctcttatta tctaaatccc tgtatatttt acctcttcta tctattacac
    27001 ctttggtaat catttgacag attaaatcaa ttataccaga accacatata ccaactggtg
    27061 cacattcatc aataatcttt aatgttggct ctaaagtatc tttatcaata attactttct
    27121 ctattgctcc tgctgatgct ctcattccac agcttatccc tccaccttca aaagcaggtc
    27181 ctgctgaaca tgcacagctc atcatataat ctttatttcc aaatacaatc tctccattag
    27241 ttcctaaatc tataaataaa acattttctt cacttgacca tatccctgct gataatactc
    27301 ctgctgttat atctcctcct acataacttg caacagatgg agctaagtac acatatgcac
    27361 tgtcatttac aaaaagacca acattttcac ccataagttt tggagatttt aaaaatggtg
    27421 gtatgtaagg ttcttgtctt aagaagtctg tatacacacc caagaataaa cttgtcatag
    27481 ttgtattccc agcagccact aatgtaacta catcttcctt atctattcca tttctttcat
    27541 atattgtttt taatagtgga tttatagttt cctcaactat agctttatga agtgtctcta
    27601 atccattttt cttagttgaa tatataattc tatttataac atctgctcca tattttatct
    27661 gtgcatttcc agaagatgct ttatctacta cctcttttga gtataggtct actaaacaaa
    27721 caactactga agttgtacca atatctattg caactccgta taaggaattt tctttatttc
    27781 cttgttctat atttatgatt gtaagtttct tttgtttttg aacatatgtt attgtaacct
    27841 taaaatcact ctttctaaat acagttggca tttttctaag tatatccaat ctaaaatcta
    27901 tttcattata tcctaggtta tttctaacat atctttccaa tctatctaca tcacttatat
    27961 tatcatctaa atttggttct tccatttcta tgtatttctt ttttatattt gttttaaatt
    28021 gaaggttatg ttcttcaatt atttttttag ctctttcaaa aatttcccta tcctcttttt
    28081 tattactacc ttctatcttc ataccatgca tagaagatga tactttagaa ggaacttcaa
    28141 tttctatatc tgatattacc tttgtacaac aagctagtat ataaccttgc tcccactcat
    28201 catctgttat atgtcttgtt ttttctgtat caacttttcc attcaataat tttactttac
    28261 acttcccaca agacacgttt ccattacaag gagcatctat gaatatatct gcatttcttg
    28321 caacctctag taatatatcc ccctcattac aataaacctc tttattgttt ggtgtaaaac
    28381 ttacttttat catgttatcc ctcccaattt gttctatata tgataaaagg aaagtatagc
    28441 taaatttgcg tgcactcaaa ttttactata ctttccccaa ttataataat atcttaatct
    28501 ttaattattc taatccagcc tcgtattctt tatcacttaa taacgtatca agttcagcca
    28561 catcagctag ttttactttt aatatccagt tttcatatgg gtcttcattt atacattctg
    28621 gctcatcttc taatttttca ttaacttcca atacctcacc attaacagga gatattaaat
    28681 cagaagctac tttagaagac tcaactactc caaaatctac tcccttagtt acagtatctt
    28741 ctacttctgg tgtttcaaca aacaatattt ctcctaattg atcttgagca tagtctgtta
    28801 tacctatata tacaacatct ccatcaatta cttttaccca ctcatgatct ttagagtatt
    28861 ttaattctgg taataatttc atttcgatag acccccaata ttatattatt gattaaatta
    28921 cttaaatcat attaatatta tatcatatta ttttaaattt tccatcaatt acattacact
    28981 ttccatagct aatgctggat gacctttttc ttctaagaaa gctaatactc cttcagaatc
    29041 gtcagctata gtttcatcac aaaccatatc acagaagttt tctattccag tcatttcttt
    29101 aactgtagca tttaatttat cagctacata atcttttaat tcttttggca tccaaactat
    29161 tctttctggt ccaccttctg cataagcgaa ttttttagaa gatatgaaat gtcttccgtg
    29221 tcccataaat cctggagttt gaactcctcc acctgtcata gaagcaagtt ctccgaaagt
    29281 cataccaact ggagtaacac ttgcaaattc tctgttaact acaacaaatc catttgcttc
    29341 tggcattata ccacagatac attcgaagca tccacaagaa gtcattgggt cttctagtat
    29401 agagtataat gtaacagatt caactgcacc ttgagatatt tggtttacag tttcatttac
    29461 tgaattccat acacctgttc tatcatctaa gcactcgcct ttttctattg gttgacaagg
    29521 acctgttggg tctaattctt tagtagcctt agcatctaac cagctaactg ctccacaaag
    29581 accaagtctt tcaggagtaa caacacaaac gtgagctggt gcaaatgatt gacataagtt
    29641 acaagaatag aaagtgtcaa cactttcatc aactaatgaa gctaatcttt catctctagc
    29701 attgtactta gctattgctt ctccttttaa ttcagaaact ttttcagcat ctgtaattat
    29761 agttatttca cacttatcaa ctactgattc aaattcatct aacatcttag catataaaac
    29821 ttctcctata tgctcaagtc taaatccttt atcaaatgca tctttagaga ttcttaccca
    29881 agccatatct ctttgtccaa cgtgcattac accttctata tagtttaaga agtagtggaa
    29941 acgtctttca agaactggct cgaaatcttc ttgcatattt ttaccagcta ttttaactat
    30001 tacagcaagt ggtaatctta atacaccatc tgcatcaact tcatctatat ttggtcctat
    30061 tatttctatc ttatggtctt caacttctgt tgcttctttc ttaacaacaa gctcccaagc
    30121 ttcagttctg tttccaccaa actcagcaaa catatcgctc tttctaattc tctcaccttc
    30181 aaatgctgct gcaaatgaaa ctgggatagg tatttcagta acttttattt ttattcctct
    30241 agcttctaat gaagtagcta ctatcttatc gtaatctttt tgagttaata ggttcattgg
    30301 aacttcaaga actgtttggt cagttataac tgggaatcct aaagctattg ctccagcacc
    30361 tgcagataca actaattcac ttaatggtcc aaatgcatta acaaatgcag gaactctatt
    30421 agctgtgtac tctaataatc cgtttaaatc accaggagtt aatccaccga atattaatgc
    30481 tgctcttact gcaacagata caacgtgtat aacagaagtt acatcatatc ctagaggtat
    30541 aactcttagc tcaagaccca tttttactcc agcttctata gcttggtcta taactttacc
    30601 aactaagaaa gttagtaaac ctttagattg gtaatctttt ataacttttg ctgctgattc
    30661 tgcatctgga cactcaccaa gaacaactgc aacaccaggt atatctcctg taactaatgg
    30721 tacaccaagt gatctgatta tagggtcagt tatatgacct gcacatggct cactatatgg
    30781 agcatccata gttgaatatt ttaatgcttc aattacttct gctgctaaag ctgtagctaa
    30841 accagcatta aaagcatgtt ctagtaaatg agttctattt attaaagatt ttactacttc
    30901 taaagcacct tctaagtccc ctaaagtgtt catcttttgt cctgttgcag catatataca
    30961 aggtaatgaa tatgctgtat cagggaaagc aactttatgc tcttttccat tcttttctat
    31021 agcttcagct aacatagctt gagccgcacc taaagcttgt tctgaccctg taaagattat
    31081 attatataga ttcattctat ttcccccttt aatatttaca cctatttttt attaactata
    31141 ccctaaaaac cctagaaagc aaatccacct tcatttaact ctaagaaaga gtctgcatat
    31201 aaagatgccc cgttgattat gtcacaagat tttacagttt tcattaattc tgggtcacat
    31261 ggattcatta tagctgaact aaatccatta gccattgcca ttgctaagaa tgcactatct
    31321 aaaacaggtc taacatgctt aggacatcca ttagatacgt tagataatcc tcctgtagtt
    31381 aaaagtccca tctcagtcat catttttata gcttctaaaa cttctacttg tttttcttgc
    31441 atacctttta taactaagca taatgggtca aatagtatat cagttggctc cattcctaac
    31501 attaagcctt tttctaatat ttcttggcag taagccatac gctcatcatt atctcttggg
    31561 ataccttctt ttgcacataa acctataacc attgcttcgt attcagctgc tatatctatt
    31621 aaatcaaatc ttgagccagc atcagcagag tttattattg gttttgcatt agttctatca
    31681 taaactttaa gtccagcttc gatagctttt ttattagctg tatctaatgc tataggaaca
    31741 ttgttgaact cagattgaag taatttgatt ccccatgtca ttatttcttc gccatctctt
    31801 tcggcaggtc ctatattaaa atctatatag tgtgctcctg cttctaattg ctcttttgct
    31861 ctttttaaga ttggagctgg gtctctttct gctaatgctt ttcttattga aggtgatata
    31921 caatgtattc tctcacctat aatcataaat ttttccattt ataatgtccc cctttaaatt
    31981 taatattaat agttagttaa tattttatta gtttgtttgg catgcttttt cttggtatcc
    32041 ttttaagaac ttaggtaatt ccatagattc ctctggtcct ataactacat tccatcctgg
    32101 taagttatct tctatatcac ctttaagtac tgcaactttt cctggaatga taaggtcttt
    32161 acaattagtt acttcttcta ccttactttc tttaatgaaa gcagagattg agtttccacc
    32221 aaatttacca gcagcccaag atgtaagaac tgaatatcca cctgcatctg gtattactaa
    32281 ccatactgga acttttgatc tttctatatc accagcaact atgaagtaag ttaatgcaaa
    32341 gtcaacagta actaatactg gagaattttc atctggattg ttgattggat aaatctttgg
    32401 ttcaactctc attggtcttt gtgggtcagt gtatatgttt tgtcttagtg caaataatgg
    32461 taatgcctta gcataactaa tatcatctat tactattata gaaccgtatt ttatagtgaa
    32521 tattgatgat aaagcaactt ccatcatagg gtttgaatta gataatctat ttgcaaatac
    32581 tattgaagga tatccaaatg ttctatcttg ctcttttaaa gctgttcttc taacttgtat
    32641 agcattagtg taagtatctt ttatgttttc tcctgttaca tctaatacta attctttata
    32701 tccagcggct tgaattaatt caactgtttc atataattct tctaagctac cagcttttac
    32761 acctaatggt aaacttgctc ctttaactac ttctatcata tctttgtagt tctctttagt
    32821 tgctccatat accattggtc tagcatcttt taatacttca acagcttctt taactacttg
    32881 tgcatcatca caagctaaaa tataagctac ttctaatcca ctgcctttta ttttatctat
    32941 taattttaaa tacgcatctt tatctccaca atactctaaa acagccattt caactttcat
    33001 ttgttcacca attcttacat agtcaacttt tttcatgtta gctattttag catctactgc
    33061 ttcatcactc atacaagtac agaatgaaac tgcatatcta tttctactta ctaatgtttt
    33121 ttcatgtcta aataatactg tttctccacc tagttcatac tcagatgcac cagcaccaac
    33181 ttttaaagct ttcattaaag gtgcagtagc ctctgataat tttgctatag cgtcatcaga
    33241 catatgtggg catttaccta cttctacagc tcctgaagca accttcatag agaaagccat
    33301 acaagttggg aatccacaat ccttacagtt tttctttggt gttaatttaa atatatctaa
    33361 agcttttaat gccattattt tttcccccta accttaacaa tttaattaag ctaatgcgtt
    33421 aaccaattct tttatagttt ctattgattt tggatgacga agtataactg cgtttgaacc
    33481 acctactaaa acacttgctg cagttgaaac ttccattgct atagttcttt cttctggaca
    33541 accccaatct ggctcatctt ctattggagc tatagcttct ttaacatgac ctacttcaaa
    33601 agctactggt gttatgatag gcatttgtaa tgtcttatca ttttgaccaa atgctgcaag
    33661 tctaattcta tccatagtag atgcaacgta ctcatatcca taaccaactg ctgaacatcc
    33721 aacattcata actatatttt cacctttaac gcctagttga gttaacaata cgtttaattg
    33781 tttagctagg tttatatcaa cagaagattc agctcctact ttatgtgcat aagccatacc
    33841 agctgatgct cctactcctt tgtagttatc ttctactgct gacataaata agcagttatg
    33901 tccatccaat gtttgagcta atttttcaaa taatttacca tctttttcat gatttcctga
    33961 accagctaca actaaaggta attttattgc ttcaattact gccttagcta catcagcaca
    34021 ttcatcaact gacttatcta atccatttgg gtcagaacca tcaaatttta aacaaataaa
    34081 atctgcttgt gtattagctt caacatattt agcccactct actggacaat tagctacatc
    34141 tttgtataat tccttatatg aatcagtcca gctttcagga taaacgtctg atatttgtat
    34201 acctattttt ggagaattac ctacttctcc atcaaaacta taaaaaggta atacattttc
    34261 cccacctaat ttaattgctt tttcccctat tcctacttca acttctgata tttttccaga
    34321 atatttttga gtagacattt taaatgccat atttttttcc cccttaagcc tattttaatt
    34381 ctaatttagc aaaaatttct ttcatagcca ctttagattt tgaatcttca ggtaaattaa
    34441 ctaaaggaat acctgtagaa tcatattcat atatcaattc atccataggt acaacaccga
    34501 ttagctctag gttatgcttt tcaatttctt ctttaacacc atcattcata accccatttg
    34561 gaactttatt tacaatcaaa agtattcttc caacacttaa ctttagttcc tcagctaaat
    34621 ctcttattct agcaacagct tgtatgctac gtcttgagca atcactaacc aataaaagtg
    34681 tatcaacatg tctagtgact tttctactta gatgttccat accagcttcg ttgtccatga
    34741 ctaagtattt gtaatgacca gatattttgt ttacttgttc tctaagtatc ccatttacaa
    34801 aacagtaaca tccttcacct tctgacctac ccattactaa taagtcatat ccttcgcctt
    34861 cttcgattat agaatttaat ctaaattgaa gatattgtgc ctttgtcata ccaccaggga
    34921 atgcattgcc taacttttct ctttgattta cttcttctct tatttctcct attgttgctt
    34981 caacttcgat acctaacact tcatttatgt tagcattggc atcagcatct acaactaata
    35041 ctggtccctt tttgtcctta accaaataat caatcaaaag ccctgtgaga cttgttttac
    35101 cagttccacc ttttcctgca acagctatat tgtatcccat tttaagactt cccccttaaa
    35161 tctagccaca gagccttatg tactctgtct gtctattata atttaggtac agaatgaaca
    35221 cattctccat gtacatcatg aagtgcttcc attagccctt cagataaact tggatgtgga
    35281 tgtattgcat cccctacttg ttctactgtt aatcctagat gaacagcaag tgacaactct
    35341 gtcaataaat ctgtagcatg aggtcctact actgctgcac ctattatctt atcagtttct
    35401 ttgtcagcta taacttttac aaatccttgg aaatgtccta tagcttgtgc ttttccaaga
    35461 cctctaaaat caaattgacc tacattgtat tctacacctt cagcttcaag ttgcttttca
    35521 gtcttaccaa caccagcaac ttcaggttca gtataaacac atcttggaat tgctctataa
    35581 tctactacct tagtcttacc taaagcattt tcaactgcta cgataccttc tttagaagca
    35641 acatgtgcta ggaaaggagt atctattata tcgcctattg cgtatatacc ttctacatta
    35701 gtttcaagat gttcattaac tactactttt cctctttcca tttcaattcc tatatcttct
    35761 actccagaat tgtcaaggtt aggtcttcta ccaacacata ctaatgcata ttgtgcttct
    35821 ataacctttc cattagaaag agttgcaaca gccttaccat caactacttc acaagtttgt
    35881 actccaatac ctgtaataac cttaatttta tctttcttaa attgtctaag tagttgttta
    35941 gctacatctt tgtcttcatt taatagtatt tggtcaacca tctcaactat agttacttct
    36001 gttcctaagg ctctaaagaa ctgccctatc tcacatccta taactccacc acctactatt
    36061 aacatagact caggtatctc ttcaagtcca agaacttcat cactagttat tacaactttt
    36121 ccatcatatg ggaacattct tggtacaact ggaacagaac catttgctag tattatctta
    36181 tctgctttta tagtttctac tgttccatca tctttagtta cttctatagt gtttttatca
    36241 attaattttc caaaaccatt aactaagttt actcctcttt tttcaaataa gaactctata
    36301 ccacttatta attggtttac aactttattt tttctttcca ttatggcagt gaagtttggc
    36361 ttaattgtac catctatttc tataccaaaa tcctttgctt cttttacagt attcaatact
    36421 cctgaagaag caagaagtgc tttagttggt atacatcctg catttaagca agttcctcca
    36481 actcttcttt tttcaacaac tgttacatct gcaccaagca tagaagcttt tatagctgct
    36541 acatatcctc ctggtccacc acctactact actatcttca tctttaattc ccccaaacct
    36601 aatataatct acaatcttgc aatactataa acctgcggca tccagtatag caggtatatt
    36661 ctcttctgcc ccaattgcca ttatatgaac accatcacat aaatcttctt cttttaattg
    36721 tttgataagt tcccctgcca tttttattcc ttcacttacc cagttttctt ttccagctgc
    36781 tcttaatctt tcgatttgtt catctggaac aaatattcct ggtacatttg cagtcataaa
    36841 tttagccatt cctggtgatt ttaaaggtac tattcctgct aataccttgc aatccatatc
    36901 ccttgttaat tctctaaact ttctcattgt atttatgtca taaagtgctt gtgtttggaa
    36961 aaatttagcc cctgctttta ttttcttttt catttttaat aattgaactt ctattggaga
    37021 atattctgga gttactgatg ctcctagata aaaatctgga gaacctttta acttattacc
    37081 agccatgtcc gtacctgcca ttaaagtctc agcagtttga agtatcccca cagaatctaa
    37141 atcaaacact cccttagctt gtggatggtc tcctacgcta gtatggtctc ctgttagtgc
    37201 caacagattg tttatcccaa atacacctgc tgacaacatt tctccttgta tagctattct
    37261 atttctatct ctccctgtta tttgaataac tggctctaat ccagcatctt ttaataattt
    37321 acatgtagca agagaagttg ctctcataac tgccgattga aagtctgtta catttgctgc
    37381 atgaactctt ccaactaacg gctttgcaca ttctattaaa tgtgaaaggt cagtcccttt
    37441 tggaggagcc atttcagtag taactgcaaa ttttccactt tctaatgttt ctcttaataa
    37501 gctcatctct aatccccctt ttaaccttct aaaaaaactt ttatgaattt gctgctgctt
    37561 ctttcttttt ctttgcactt aaacttcttg gattattttg cttagaatag tcttttggtg
    37621 gtcttatttc tgctaagtta tctaattgtc ctatagcttc tagtctttca tatatcttta
    37681 tccaagcaca atcattctct gagtttactt cacacttacc atttttagct ccaccacaag
    37741 ccccattcat aagaccttta gcacacatag ttactggaca tatcccacct gtccaaccaa
    37801 gttcacagtc tccacaagcc ttacaggctt cttcatattc tccaactctt tgtacttccc
    37861 ctataaacaa agtattgttg gctggataaa ctggcttatc ttttaaattc ttaactattg
    37921 tctgtgtacc atctccacat gctaaagata aaactgcatc agcttcctta gtctcttctt
    37981 ttagagcctt taaatccttt ttagacttta aaaggttaca agcagggtca agcattacat
    38041 atcctaagat ttttttgcct tcaccttcaa gagtttcctt catttttaaa acttcttctt
    38101 ccccaccact tttacaagtt gctgcacatt gattacaacc aactaaaacc agcttgtcaa
    38161 aatcttttaa gtaccctagc acttcttcta atggtttatt ttcagaaatt atcatatcta
    38221 cttcccccct aaaccttcca catatatata tctatttatt gttttgtaat ttgcaagcct
    38281 taactacatg ttttgcaagt atagatgttg taactgaacc aacccccgct ggaactggag
    38341 ttatcattga tactttgtct aaaactgcat ttgtatcaac atctccacat aaatttcctt
    38401 cttcatcaac atttatacca acgtctataa ctaccgctcc atctttaaca aaactttcat
    38461 caaccatctt agctctacca atagctgcta ttagcacgtc tgcctctgct gctacacctg
    38521 atagattttt agtttttgaa tgacatattg taacagttgc gtgttcactt aataaaagca
    38581 ttgatactgg ctttccaact accattgatc ttccaagaac tgttacctta cttcctttta
    38641 aatcaacatt atagtgtttt aatatctcaa ctactgctgt aggtgtacat ggtggaaatc
    38701 cacttttatc cccttccatt accttagcag agtttattgg actaaaacaa tctacgtctt
    38761 tttccggtgc aataacatat tttataactt cttcatttaa gtgttttgga agaggtctaa
    38821 aacataatat accattaaca tttttgtcat cattaactct ctttaataca tcaatatatt
    38881 cctcttgtgt tatatcctca gctaactcta acacttctgt tgttatacct atgttttgac
    38941 atctctttag tgctcctctt tcataagata aatcatcact tcttgcccca actctaacta
    39001 ttgttagttt aggatttata ccttctttaa ttagtaaatc gacttctttt attaattctt
    39061 cactaatctt atcagctaca ggttttcctt ttataatttg tcctttagtt gacattcctt
    39121 ccatacattc acaactcccc tacaagcaaa cttaaattaa tttattctat ataccacata
    39181 ttaataacat agtatctact ttcgtcattt aaaaattatt ttccaagagc tttttcaact
    39241 ttggcataaa cttcatcaca aatttttaca ccatcttcaa ctaacttatc tacttctgtt
    39301 tttaccttat taacatattc tttatcttgt atagaattta tatttataac tacatttaat
    39361 tgtccaccaa gtatagcagc tcttaaacac tgaactccta caccaacatc acttatagca
    39421 agtcttgaac ctttatcaac taaatcttca tgtaacttaa tagcttcata gcaaactctt
    39481 actatgttta atggtacttc acaagcaact tttaatgcct tttccattgt ttctgctttt
    39541 attctttttt cttcttctgt ttctttagga agcccgtaag cttttgataa tggtaagaaa
    39601 cattctgcat catcatctat catttttaat aaatcttttt ctaactttcc tgccttactt
    39661 aatatctctt ttacactttc ttcatactca gcatacttct tcttccctat tgtaaggtta
    39721 cataccatac tacctaaagc catacctatt gcacctacta gtgcagcagc tcccccacca
    39781 cctggtactg cttctttgga agatagtact tctacaaaat caacacaagt tttatctgct
    39841 attttcatga taatcctcct tgaaaggatg taggaaaata tctcaaattg ttcgagatat
    39901 tttacgaact attttaagat atctcctact ctttatttat aaattaattt ccttagaata
    39961 atccagctat tactccattt tcatcaacat ctattttttc tgctgctgga acttttggta
    40021 atcctggcat cttcattatt tctccagtaa gtgcaactat aaatccagct cctgctgaaa
    40081 ttgttgcttg tcttacagtt attctaaatc ctgttggtct acctaattta gtttggtcat
    40141 cagttaaaga atattgagtc ttagccatac atactggaac tttagtaaat ccaagttttt
    40201 ctaagttagc tatttcctta tcagcttcag gagtataatc tacaccatct gctccataaa
    40261 tcttagtagc tatagcattt atcttgtctt ttatagataa atcatcttca tagcagaatc
    40321 taaagttatt ttcttcttca tccaataatc ttaaaacttc tttagctact gcaattccac
    40381 cttctccacc ttttgcccat acttcagaaa gagcaacatt aacacctaat tccttacact
    40441 tgtcttcaac aagtttaagt tcagcttcag tatcaagtgg gaatctgttg attgcaacaa
    40501 ctgctggtaa tccatatact tgagttatgt tttcaacatg ttttaataag tttggaagtc
    40561 ctttttcaag agcttctagg ttttcgttat ttaagtctgc tttagcaact ccaccattgt
    40621 attttaatgc tcttacagta gcaactatta taacagcatc tggttttaag tttgccattc
    40681 tacattttat atctaagaat ttttctgctc caaggtcagc accgaaacca gcctcagtta
    40741 ttacataatc tgcaaagtgc atagccattc ttgtagctat aacagagtta catccatgag
    40801 ctatatttgc gaatggtcca ccgtgtacaa atgatggtgt tccttcaaga gtttgaacta
    40861 ggtttggttt taaagcatct tttaataatg cagccatagc accattagct tttaattgtc
    40921 tagctgttac aggttcacct tcgtagctgt atccaactat tatgtttcct aatctttctt
    40981 ttaaatcaga tatatcactt gccaaacaga acgctgccat tatttcagaa gcaacagtta
    41041 tatcgaatcc atcttgtcta actgctccat cacctttttt acccatacca tcaacgatat
    41101 ttctaagttg tctatcgttc atgtctacac atcttctcca agttattttc ttagggtcta
    41161 ttctaagtgc atttccttgg tgaatatggt tatcaagcat agcagctaaa agattgttag
    41221 cagctcctat agcgtgaaaa tctcctgtga agtgtaagtt tatatcttcc ataggaacaa
    41281 cttgtgcata tcctccacca gctgctccac ctttaacacc aaatactggt cctagagatg
    41341 gttctcttaa agcaactaat acatttttgt ctagtttagc aaatgcatca gcaacaccta
    41401 tagtagtagt agtttttcct tcacctgctg gagttgggtt tatagctgta gttagtatta
    41461 acttagcttt tttaccagtc tctcttttta gtagattgta gtcaactttt gctttgtatt
    41521 taccataaag ttctacatca tcttcaccta gtcctaattt ttttgcaacc tctctaatat
    41581 cttgaggctt agcttcttga gctatttcaa tgtcagattt aaatcccata actgaatctc
    41641 ctcccacaac ctaaatagat ttaaaatata atttttgtaa aaattgtatt aatatgtaaa
    41701 aattatattt tataagataa ttatacatgt aaaattactt aaaaactagc tactaagcta
    41761 ttaaaatatt caaacttaat agctagttat ttatctaatt acttacttat tacctatcta
    41821 ttgcctatgt ctaaccttta accaacttaa aatcccaaat caaaatttct atctatttta
    41881 tttatcctta agtgacatta atttatcttt tattgcttta atctgttctt tcgttgtttc
    41941 actagaatca tatggagatt gattagctct atcagaatca ataacatctt ggttataata
    42001 aataaatcct aaagattctc catcttctaa gttttggatt ataaattctt catcttcctt
    42061 atttctaatt ttatttccta ctacaaatac tttatttaca cctatatcat gtccaagttt
    42121 cttaactttt ctataagtct gtagacttct ctctcctggt tctacaacta ctataaaagc
    42181 atctacacct tgggctgttc ctcttcctaa gtgttcaatt cccgcttcca tatccataac
    42241 cactacatct ttattttgta gtattaaatg tgagcagagt ctcttcaaaa gaacatgctc
    42301 tggacataca catccagtac caccagaatc tacggttccc aatgtaagta atcttactcc
    42361 attgtattct ttacagaaat tttcagggat atcgtctact ttaggattca tcttaaacat
    42421 ttttccaaat gaacctacag aagcagctgt tctatctgaa actaattttt tcatttctga
    42481 tataggtact attgattcat atacttcttt tggaaaacct agtgctaaag ctaaattagc
    42541 atcagggtcg gcatcaacag caacaactct gtatccgtct tcagcaaaca tcctagagag
    42601 cattgaagaa aaagtcgttt tacctactcc acctttacct gttattgcta tcttcataat
    42661 ccctaccacc ttttattact atttgctttt tagtagttaa ttttacagtt aaatattttt
    42721 tatactctat atttttatac actaaaaata aactacagct agtccttaca ggaaccaatt
    42781 aaatttaccc tactagcttt tcaaagcagc atgtatagtt ttattattct ttaatattgt
    42841 ttatatttta tttattcagt atattcatta tattttgatg ttctttactt taatatttga
    42901 ctttattcaa ctttattcaa ccagaaactt cttataaaaa cgtttattct ataacttcac
    42961 tattttttaa gcttcagcct tttctgccat cttttcttca actaatgctt caaagtgaac
    43021 acgttttttc tctatatctt ctattattgt agctgctaac tcttttggat ttgtatttac
    43081 agtaaatgta gctccaactt tatcttttaa ttcactagtt aatatatcca ctgctcttga
    43141 agaaccagct attggaggca ttattcctaa ataagtgtct ataccagaag ctacaacata
    43201 gcatcctata gcaactgctt tttctgacat ccactctgga gctataccta caactggaag
    43261 gtcacacata tccatatcta agtaattagc tgctgctcca actaaatcta gtatacgact
    43321 tatatcaaca caagaaccca tatgtagtac tggtgggatt cctactaatt tacagacagt
    43381 tgcaagacct ttacctgcat atttttcagc cgcatcagat tccattaaac caaacttagc
    43441 tgctgctgaa gctccacaac ctgtagtaac tactattatg tcgtttttga ttaattcttt
    43501 cattattgtt acgtgagcct catttgaaac tcctttagca ttgttacatc caactacacc
    43561 agctgctcct cttaatactc cagattttaa acagtctgtt aatggcttaa ctgttcctgc
    43621 tgggtctata tgagagttta caactctgtc taattgattt actactgctt ctacactata
    43681 cccaactgtt gcgcctgatt ttaattcagg tataagtact tttgatttat ctctattttt
    43741 aaagtttaaa atagcttctt taactattgc tttagcatca tcaagtgctt gttcttctct
    43801 aaattcaata taagttgaac ctgttatctt agcttttgga gaagttgtta caaatttagt
    43861 atggtaacaa tctgcaactc tagctaatgc agggaatata cattgaacgt caactattac
    43921 agcttcaact gctccagtta ttattgcaag ttcttgttga tggaagtctc ctgctatttt
    43981 tacaccatgt ctcattgtaa tctcattacc tgtacaacac atacctgcta agtttattcc
    44041 atcagcacca acttctttag ctaaagctac taagtctggc tcttctgatg ctaaaactat
    44101 catttctgat aatgctggct catgtccatg taatattatg ttaactttat tttcttctaa
    44161 tactgctaaa ttcgcctctg ttcttcttgg cactggagtt ccaaataaga tatcgcttag
    44221 acgagtacct atcatagaac caccccaacc atcagccata gaagttctaa gactcatgtg
    44281 tattaaacta tctatatcac cagtacatcc tatatgagta gagtgcatta ttgttgcaat
    44341 ttctctatct atagctcttg gctctatagc gtattctttc catatttttt gtcttggttc
    44401 tggtgcattt tttataaatc ttaatgtccc aaaaggtttt ccaaattcca ttaatgcaat
    44461 ttctgccact tcatgtgcta catcatagat atctctacct tctgtctcta catcccattc
    44521 tttagctaaa gtaattaact tagcttcgtc tcttatttta tagtttccat ttggatcagc
    44581 taatgctaat gtatgtgcta tatctctagc atggtctgaa tgggcagctg tcccaccagc
    44641 aaccattctt gcaaagtttc tacctactat agtatgctca tctgctccac ataaccccct
    44701 tggagtctta gggcttattc tacatggtcc cattccacat attctacagc aaacaccttg
    44761 aagaccaaaa ccacattgtg ccttaaagcc ttcttttcta tcatacattg tttctacgcc
    44821 ttcttctcta gctttagcta tcatcttctg gctgtttaaa tcaattgtta acattttttc
    44881 atccatattc ctatcccctt tttttgattt ttaaaatccc ccaggtgact gacttcatgt
    44941 cataaaataa taaaataaat gctttctaag ttgattatat actaattttc agtgctttgc
    45001 tttagattta aatatttttt taacaaaatt agataataca taaaaatttt attttctaca
    45061 cttaatttaa gttgatttta tcgcttgttt ttggctattt gttaatatct aaacctactt
    45121 ttttgatact tcagtttaat taaattatgt tttgattttt ttaaatcaaa tttgaaattt
    45181 ttctagtcat ttttatatta ttgcagattg tttgtgtatt tattatcttt cactactgtt
    45241 tggacttatt acagattttt actccctaaa cttaattagt aaaaacttct tagaatagca
    45301 ttttttggac taattttttt gaattttttt atttttccta ctttaatatt aattatagct
    45361 tcaaattgaa catttgtata tattcatttg aagctataat tattttttat ataaaacttt
    45421 tttaatacag cattaattta gacattttga ctattttttc tactttaatt catttatttc
    45481 aagcgattta tcctatttca tatttttagc tacaatagcc ccatatgcaa tagaatataa
    45541 tttagattca tgtgaatcag ctcttgacac taaaactata ggagcttttg cacccataat
    45601 tatacctgct gatttagagt ctgccatata tgtaaaggct ttccctattc cattaccaac
    45661 ctctattgtt ggaaccaata tgatatctac atctccagat acttcacttt taaacccttt
    45721 tatctcacta gcttcttttg aaacagctaa atcaaaagcc agaggacctt ctacaattac
    45781 attttcacca aattctcctt ctttacaagc ttttgctaac atatctgcat ctacagttgc
    45841 ttgcatctta ggatttactt tctctttagc tgccaaacat gcaactttta cagtttccat
    45901 tcctaaagct tttgcagctt ttatagaatt ttttaatatc tttgcctttt gttcataatc
    45961 aggagctata ttcatacctc catctgtagt tataagtaat ttatggtatt tttctaactc
    46021 atataccata acatgactta ataaactatc agttctaaga ccatagtctt tatttaacac
    46081 ttcttttaat atgacagatg tatctaataa tcctttcatt acaaagtcgg cttctttact
    46141 tgatactaat ttaactgcta tttctgcaca ctctttgata tcatccttat ccactatttt
    46201 gataccactt aaatcaaatc ctatttcttt tgatatttct cttattttgc cttcatttcc
    46261 aaccaatata ggagtaatta tatttctttc tacagcatcc tttattgcca ttaaaacttc
    46321 tttatcatga gctgctgcta cagagagtac aattttctct cctcccttaa gttgttctaa
    46381 aatatcatct aattttttta tcaaaagtaa cccctccctt atatatattt aactaaataa
    46441 taccatattt gctatacctt ttctcaattt attttttatg ttataaagaa tttatataac
    46501 taaaagacag tttaatattt tattctggga tttcatcaat aactcttaaa agctttgcag
    46561 gaacaccacc tacaatagta ttttctgcaa cattttttgt tacaactgct ccagcagcga
    46621 taattgcatt atctccaata gtaactcctg gaactacagt tacattagca ccaatccata
    46681 cattttttcc tattgtgatt ggagaaggat aagttgtacc acgtttctct ggtgcaatac
    46741 catggttaag tgtagccaat accacattat gcccaatttg cgtattatct ccaatctcaa
    46801 tccccccctg gtcttgaaaa tggcaactgc tatttataaa aacatttttt cctattgtga
    46861 tgttttttcc acaatctgta taaaatggtg gaaacataaa aaatgattca tctacctttt
    46921 ttccaattaa ctcagaaaat aaactacgga cttcttctgg ttcatgataa gaagaattta
    46981 acttacttgt gattttcatt gcttcattac tcaacttaac cataaattca tgtatttctg
    47041 atttactaga aacaggtttt ctttgattga tatgtgttaa aaattcattg atattcattt
    47101 tatacatcct ttcaatatgt gctttaattt atttgtacat tctaaataat attttaataa
    47161 aaattaattt aatttatttt tattaaaata tcattgcttc ttttagtgta atatacaatt
    47221 atatctatat caaatatcta tagtaaatac ttaactatac ttaaaaagca tataaattga
    47281 tataattata taatagataa gttaatattg aggagggata attatggaaa taagagtatt
    47341 aagatatttt ttagcaattg caagagaaga aagtatatct ggtgcggcaa cctttttaca
    47401 tataacacaa ccaacacttt ctagacaaat tatggaactt gaagaagagt tgggagttaa
    47461 attattggtt cgaggaaata gaaaaatcac cttaacaaat gaaggtaggc ttttacataa
    47521 aagagcagaa gaaattatat cattagttga taaggttgaa ttagaatttg acaatcccaa
    47581 tgagattatt agtggtgata tatatatagg aagtggtgaa actgaagcta tgcgacttat
    47641 agctagaact gcccatcatt ttcatcaaaa ataccccaat gtaagatatc acctttttag
    47701 tgggaatgct gatgatgtga ctgaaaaatt agacaaggga ctgcttgatt ttggtatttt
    47761 aattgaacct gcaaatatac agaagtatga ttatgcacaa attcctgcta ctgatgtatg
    47821 gggtttacta atgcgtaaag atagtgccct tgcatcacaa agcacaataa atccaaaaga
    47881 tttatgcaat atacctctta ttatttcaag acagacactt gttgataaag caatttctaa
    47941 atggcttcaa gacagtaatg aaaaactaaa cattattgca acatacaatt tagtttataa
    48001 cgcttctctt ttggtagaag aaggtctggg ctacgctctg tgtttagata gactcgtcaa
    48061 tactacagaa aacagtaatc tttgttttag acctctatct cctcctttag aagctaaatt
    48121 aaatattata tggaaaaaac atcaaatatt ttcaaaggca gcagaaaaat ttttacttca
    48181 aatacaaaaa gatttttctt ctatcatgtt ggatacatct aagttggata cacctaaaga
    48241 aaaataaatc ataataaaag gtgagagtgt ctcaaaatga actttgcact gtataaggca
    48301 ctctttttta tacaaagtaa aatatatgtt catcatttca gcactaaaaa agaggcttat
    48361 ctctattttg agatagcccc acttaaccaa taaaattaaa tacaacttaa caatatcctt
    48421 acttatttat tctaagttct cttagacaag caatagtaat ttcatcttgt ggatttaatt
    48481 cataagctct ttctatatag taagttgcat catcaatatc accattattt aaataagcca
    48541 ttcctaaatt gcaaagtatt tctgggtctt cctttatctt agccgcttgt tcaaaatact
    48601 ctattgcttt atctaaatta ttcttataag cctcacaaag ccccaattcc actatagtat
    48661 ccacttgatt aggctttatt atcaatatct tctcaagata catcttagcc tgctctattt
    48721 cgcccatacc cttatatcca agtgctatca taaacagcaa gttccaccaa tccatatgtt
    48781 cttcttctaa tggaagtaac ttctctaatc cttccttaaa cttaccttgg aatacaagtg
    48841 tatatccttc ttcatattga actttaaagt ccatcttgcc cagattctct tgtacctcag
    48901 ctactaaatc agcatctaac cctagcctta acgcttcttc ccaagtcagc ttagtcttta
    48961 aatattgacc ttgattataa taatggtagc ctaagtgata ataacctaat gcaaaattct
    49021 catcaacatc aattaccttt tcaagcttag ccatggcttc aagtaagaat gcattcattg
    49081 ccttatcatc catatctttt tgatactgtt tagctatctc ttggcaaaca atcgcatagt
    49141 tatacattgc atctaaatca tctggataca ttgttataaa tgcttttata tatattaaag
    49201 aatctgtatg ttcaccaatc tcaaagtatt ttctcgacat atatcccata tacgatttca
    49261 aatccaaatc aatatctttt gataaagcat ttaaaaactt ctcatactct gcattgtttt
    49321 taaacttact atctattcca attatatata tcattgcatc tgctatagac attgaattta
    49381 acttatcttg agcagtcttt tcttttatcc cttttactaa tacctcattt tttataggta
    49441 catctaatcc accttttggc acttcatagc tttttaattt aaactctcca ccatgtttta
    49501 tagttataaa agctaattct tctgcttttt ttagcaaata tttttctatc ttaaaatcca
    49561 ttttatcctc ctaaatactt aaatctctac tttatgagtt ttagatttct caaatatttt
    49621 tttatcatca tactcaaata agactacatt ttctacttct cttatttctg tatttatatc
    49681 attttttaaa tccacaacat taaatctaaa tggctcaaaa tgaacatatt ttattatatg
    49741 tttagctggt ttatcaacaa aactaggtaa atatgttgat aagttatcat tatcttgtaa
    49801 aaatacatgg catctattct taaaatcatc cacatctagc ttattaaaaa actgtggtat
    49861 atttgatgtt ttacccagtg atatatagtc atattttaat atatcgttga atacatcatt
    49921 atctatgttg attttttcat tatagaaatc catcaatatt ttatataact gattctttcc
    49981 ttgtgccaaa tcaaagtagc cattttcatc aaaatacttg gcaaaaacct caaagaattt
    50041 aaaagggctt tttttataaa atctgcctat aatatatctc atagataaca caaagttttt
    50101 agaattgtag tatctctcca gtatatcttc tatatccttt agcttcaaag tttcttcata
    50161 gcttatataa ttattgtata aaaactcata tggagcataa tccttatatt taaaaccatg
    50221 ctcatctgca acttttctca tacctgtccc tttaatcatc tttaaaaagc ctaattgcaa
    50281 atgctctata cctagattaa atacatcatt aaaagaattt tcaaagctct tataatcttc
    50341 ataaggcagt cctgcaatta agtctaagtg ctgatgtata tttctataag atgctacagt
    50401 ttgtacaaca tgagacaact ttttaaaatc atcccttcta cctactgcat caagtgtttt
    50461 ttcattcgtt gactgaacac ctatttcaaa ttgaaaaaga ccttctttac aatcagccaa
    50521 aaactcaagc atcttatcat ctatcaaata cgctgtaact tcaaaatggt aagttgtata
    50581 tccattatca tttttcataa ggaaatccat gatttccata gccacttttc tatttgcatt
    50641 gaatgtccta tctataaact ttatctgtga tactcttgca tctattaaag cttttaaatc
    50701 actctttatc ctgtctaaac taaaatacct tagacctgga atagtagatg ataaacagta
    50761 ttggcagtta aaagggcaac ctcttgatga ttcataatac actattctat tttcatattc
    50821 ttttggattc aagttttcat aaggactagg aatctcatcc aaatcttgaa gtaattccat
    50881 aggcttattc actattatct cattgccttg tctatataca agtccattta catcatttat
    50941 ttccatcttt ccttgcaagt gaagtactaa gtctctaaaa attaattctc cctctccata
    51001 aagtatataa tccacaaaat catacttttt cattgcctca taactatcat aactcacttc
    51061 cggtccgccc aaagctattt tagtattagg tctaattttt tttagattat cacaaagttt
    51121 aactatatct cccacattcc agatatatgt tgagaataat attatatcat attcattttt
    51181 atatatatcc tttaaaatat agtccaaatc gttatttatc gtgtattctt tcatattaac
    51241 ttctatcaaa tctcttacaa attcttttag atatcttata gccaaatttg tatgaataaa
    51301 cttggaattt aatgttgtta ataaaatttt caaatatttc tcacctcttt ttaagattat
    51361 actgtctttt tgtacccctt ataggttaaa atagtatatg taaagtctaa ataatatcta
    51421 tataattaat ttattaattt caagtaatgt gaggaaagga agttttttat ggaattaatt
    51481 gaaaaagtat ctatcaactc tttatcaaaa agagatttac tacttattat aaagtctctt
    51541 gaatacacta atgaaaatac tcaaattagt gatttcattg accttaggaa taatatagta
    51601 aaggaattat gttttttaac tgacactaag gaaaaagatt ttttagatta tctagaaaaa
    51661 aatagcacac tctaataacc taaacctttt taaactttaa tatataaata cctgatttag
    51721 aatttatttt tatgcttaat atattatcat taaaggtttt cgacataact gttatttgat
    51781 taaatatagg gtctattata gtattacctt cttcaagtct tataagactt cttgggtcta
    51841 tgcttttatt atatgcctta actccaattt tatattttct caatttaaca acatattcgg
    51901 acatagaaaa aataaaatct atattatctt catttaattt actatcttca cccaaaatgg
    51961 ataatataga tttttttatg ctattaattc cttcattttc tacagttcta tcttccatat
    52021 atacatcata tagaacattt aaaacattta ataaaatact ttcttcatca taatcttcag
    52081 atttcaaatc aatgtactta tcaattaatt gtattgcttt aatccttgcc atctgaaact
    52141 ttacaacatc tgatttgtct aattctatag aaaatcctat tatcttgtct ttaatactct
    52201 gtagtaattc gacatactct attttactat tatttataag attgtgcata atggaattat
    52261 acaccacaga acctaataaa taatcaaata aaagttcttc ttttttaaaa taaataacat
    52321 acttttttat tagtttaata acctcatctt cacttttttg aatattagta tttgataaaa
    52381 ttagtggtaa taaaatattt aaaaaattga tatttcctat tttttctcca taaaatctat
    52441 agtaaataag ttcatctctc agtctatttt cgtctatata cacacatctt tgcgttttat
    52501 catctattaa ggattttgta tttattatag ttaaatcttt aagagcccta cttgcactac
    52561 taaaagaaga tgtgtagact ttttttagta attcgtcatt cataaatata tcctttctga
    52621 aaaattgaat gtaaataaat tgttattaaa aaaaaagaga cagcccgttt aagaagctgt
    52681 catatatagg gggatagtag tgtacaaaaa tcattgtaat ctactatcta tatattatta
    52741 tacgatacta cttttttata tgtaaagcat cagttttcga catccctata ttttacagtt
    52801 atacaaattg cgtactaagt tcaattttat tctttttatt tcaacatttt atcatgctac
    52861 attctttcag gagcgtgcat tcccaacaat ttcagagaat tttctaaagt ttgttttgtt
    52921 gctaaaacta atgcaagtct tgcttttctt atttccaaat tttctactaa aattggattg
    52981 tcatgataaa atttattaaa cgcttgagct aaatctagca taaatctagt cactatatgt
    53041 ggctcatttt tctttagagc aagtaaaata ttcttattga atgattctat aactctaaga
    53101 acttctgcac tatcttcatc agctaataga ctataatcta tatcagaagt cacttctact
    53161 tctgcttttc ttaaaactgc acagcatcta gcatgtgtat actgaacata tggtccagtc
    53221 tcaccatcaa aactaagcgt tctttcccaa gagaaggtat agtctttaat tctactatta
    53281 gataactctt ggaatactac tgccccaaca cctacttgct tagatatttc atccacattt
    53341 ttagcatttg ggtttttagc tagtataatt tccttagttt tatctatagc ttgatttaaa
    53401 gcatcttcta aaaatactac tcttcctttt ctagtcgaca tagtaccttc ttcaagtgca
    53461 accataccaa atccaacatg aattaaatct tttgcccaat catatcccat aagctcaatt
    53521 accttaaacc attgttggaa atgtaagttt tgttgagaac caactacata tatacacttg
    53581 tcaaaatcat aagtttcttt tctatatatt gcagcagcta aatctcttgt catatataac
    53641 gttgagccat cattcttagt aataagtgct ggtggcattt tatactcttc taaatcaaca
    53701 attcttgctc ctttagactc ttttaaaaga tttttctctt ctaatagttc gataactctg
    53761 ttcattttat cagaataaaa actctctcct gctaaagaat caaattctat atctaaaagt
    53821 ttatacactc tgttaaactc ttttaaactc tcatttctaa accattgcca taattcttgt
    53881 gcttcttcgt caccattttc taatttatta aaccatgctc ttgcttcatc ttccatttct
    53941 gggtgttgtt cagcttcatc atggaatctt acgtataatt ttagtaattc tggaattgga
    54001 ttagactcta ctacttcttt ttctccccac tttttaaagg ccactattaa cttaccaaac
    54061 tgagttccat agtcacctaa atgatttatt cttatagtct tgtatccttg cgaatcatat
    54121 atcttatata aagcattacc tataactgta gttcttatgt gccctatatg gaaaggtttt
    54181 gctatatttg gagaagaata ttcaactatt acagttttat cttttccaaa atcactatgt
    54241 ccgtaatttt ctttttcatc taaaactttt ttaattacag tttctgctaa ttgagattta
    54301 tttacaaaga aatttacata tccgcctaat tgtattactt ttgttatctc tccacttggt
    54361 tctatacttt ccgccaattc acttgctatc atgtttggag cttttctaaa cactttggct
    54421 aatttaaagc atggaaaagc atagtccccc atatccttat ttggtggaac ttctataagt
    54481 gcctctatct cttctttcga taaatcttct attttttctt taaggcaatt tgatattgcc
    54541 accttaaaat cttgcattct gttgctcctc tctacattgt tcctggttta tattgtgctt
    54601 atctctttat gttaaatcaa atttcgtgtt ttttcaagta tttcattaca gtgtaaaaca
    54661 ctttagtaat tatgttttct gtatatatta aaaatactat aattgcagtt tttaatcaca
    54721 ctattattga ttttttataa gacttttttc tattttattg tttcttgtac tatccagttg
    54781 actttatata ctttttttaa tcttttatct attttcatac gtcaatgcta attttatata
    54841 cttttctttt aatcttttat taatttttat acatcaatgt taactttata taagtttttt
    54901 taatctttta tctgttttca tacatcaatg tcagctttat atactttttt tactttttta
    54961 tctattttta tacatcaata ttagctttat atactttttt taatctttta tctattttct
    55021 ataaatcttt ttcactctta acttttattc cttcttcttc taatagcctt gctgttatac
    55081 ctttccctgg tatcttttta cctgaaaaac taccatcata tattagatta catccacaag
    55141 aggggctacc ctcttttagt attgcttcgc tacatacata taaatttgct atttttagag
    55201 tttcattagc ccctcttaca aagttttctg ttacatcctt attatcttta gtaattactt
    55261 ttccatcaac tatctcagca ggtggtcttg gtgtagatag accacctaac tgctctgggc
    55321 atacaagtgt aaattctttg ccttttaaat attccttgac tttttcatta tcattattat
    55381 cgccactata tttacaattt attcctatta aacatgcaga taccaatatc ataaaaatgt
    55441 gctcctatac aaattcttaa tatattctca tacaaattac taatgtattc ttatacaaat
    55501 tattttaatt taacaattgt tactcctgct ccaccttctc catattgacc acctctttgt
    55561 gattttacat gtctatttct tcttaaaatg tcttgtagcc ctgcttttaa tactcctgta
    55621 cctattccat gtattactgt tacagactct aaacctgcca catatgcatc atcaagatac
    55681 ttttctactt ccattatagc ttcttctagg tttaaccctc taaggtcaac ttcatttttt
    55741 acactaccag attttgacct tataatgttt ctcgttgatt tagttacatt tgttgaaaca
    55801 tctttgcgtg ttttttgtaa agacttaaaa ggtagagtca tcttcattat accaatttgc
    55861 actactgctt cttttctctt tttatctact gaaactacac taccattttg atttaaagtt
    55921 attaccttaa cttcttcacc tggctttaag tcttttatct ccttatttga tacctttgga
    55981 actatcatac tttttactgt tggctgaaga cttcccatag agctggtcaa ttcttttcta
    56041 agttcttcta tcttacgatt cttttctttt gaagctcttt cttgttcaag acttctaagt
    56101 tcttttatta taatatctac ttcttcttta gcttgtctta taattgaaaa tgcttctgat
    56161 ttagcttttt caatcatctt atctctttga ctgaccaatt tttcaagctt ttcgtcatac
    56221 tctactttca gtttttcaat ctcttctttt aatctttcag cttcttctct atcttctact
    56281 gctttgattc tattcttttc aacattctgt aacacatctt ctaaagctat gttttctgta
    56341 tttatatatt ctttagcacg tgaaatcaca taatcactta gcccaagttt tctagaaatc
    56401 tcaaacgcat ttgattttcc gggaacacct ataagtaact tatatgttgg gcttaaagtt
    56461 tctatatcaa attcaactgc tgcattttct acacctggtt tagtaagagc ataattttta
    56521 agctcactat agtgagtggt agctatacat ttagctccta cagaatttat atcttctaat
    56581 actgctattg caagggcagc tccttcaaca gggtctgttc ccgctcctaa ctcgtcaaat
    56641 ataactaaag agtctgctgt tacgttttgt aatatagata ctatattcgt catatgagat
    56701 gaaaatgttg atagactctg ttcaatactc tgctcatctc ctatatctgc aaatacatta
    56761 tcatatacac acatactact tccataatca gcaggtatat gaagtccact ttgtgtcata
    56821 agtgcaaata gacctacagt ttttattgta acagtcttac cacctgtgtt tggacctgtt
    56881 atcaccaatg tatggaagtc tcttcctaaa taaattgtat ttgctactac cttcttttta
    56941 tccagcagtg gatgtcttcc attttttatg tttaaatatt tatcctcatt taaagttggt
    57001 tctattcctc tcatctgtat agaaagtttt ccctttgaaa atgcaaagtc caatcttcca
    57061 agtatctctt gattagaaat taagtcttca ctaacttctc caaccatagc agaaagctct
    57121 gataaaattc tttctatttc ttcttgctca cctagtttta actgtctcaa ttcattgttc
    57181 atctctacta tagtcattgg ctctataaaa agtgtcgcac cagaagatga ctggtcatgc
    57241 actataccag ctacttgcga cctatattca gattttacag gtactacaaa tctatcacct
    57301 cttagagaaa ttattgcatc ttgtaagtac ttttgataag tagttgaact tattattgaa
    57361 tttaattttg acctaatgga ttgatttttt tgggctattc ttcttctgat atctctaagt
    57421 gtacttgaag cattgtcaga tatttctact tcactaatta tagcattgta tatctggtct
    57481 tctatgtcct tgtatacata tagagaattt gatagagatt gtattattgg ataattaaaa
    57541 tcttcttcat cactactaga taagctattt cttaatcttc tagccactct taaggtatct
    57601 gctatcataa tcagacttcc tgggtcaaga gaagcaccta tataagctct ctttacctta
    57661 tcttctatat catgaatacc ttccaaccct actgaacctc tctttataat aattgattga
    57721 gcttcactag tttcttctag catagatttc acttctacaa aatcagtatt tggtactaaa
    57781 ttttctatat attttagacc taaagaagat gaggctttct tctttaacaa atctattatt
    57841 ttattgtatt ctagaactct taacgatttc tcattcattt tctatattca ccatcctcga
    57901 tattttaact tttttattta attttaaaaa tgtatgtttt caagcatttc caataaaaac
    57961 tgcaagtttt atttcttttt catttctaaa attattatat tttttctctt ttagatatat
    58021 tttacacata ttttgtatta tactatgtat gtagctatct atatattata cataaacatg
    58081 ctttatttgt aatataatct gttaaaaaat cttctttaat atttttaaag gagtttattt
    58141 tagcttataa aaaaaaatag ctacttatat agataaatta aggaggaaca tgagtcatgg
    58201 gaaacgtatt agaaggatta aaaccagaaa gtgtttttaa aaactttgag aaaatatctc
    58261 aaattcctag aggttctgga aatgaaaaag gcataagtga ttttttactt agctttggta
    58321 aaaatttagg tcttgaaact attcaggatg aaagcttaaa cataataata agaaagcctg
    58381 ctacaaaagg atatgaaaat tgtccaggtg tagttcttca aggacatatg gatatggttt
    58441 gcgaaaaaga aaagaatgtt gaacatgatt ttcttaaaga ccctataaaa ttaagaattg
    58501 atggtgacat gatatatgct actggaacta ctctaggagc tgacaatggt atagctgttg
    58561 ctatgggtat ggctatatta gaagataata ctttagagca tcctgcacta gaagttttag
    58621 ttactgttaa tgaagaagat ggtatgaatg gtgcagatgc actagaccct agcttaatta
    58681 aaggtcaata tatcctaaat atggactccg aggaggaagg atacttatta gttagctgtg
    58741 ctggtggtaa aacttgtgtt gttagtttac ctgttgaata caaggaagtt aaaggtgaca
    58801 aacaaggatt attagttgag gttactggac tattaggtgg acactctggt atggaaattg
    58861 ttttacaaag agcaaatgct aacaaagcaa tagctagagt attaagtgta ttgaatgttg
    58921 attatgaatt agcttctgtt gatggtggta ctaagcacaa tgctatacct cgtgaagcta
    58981 aatgtgtaat agctgttaat aaagctgatg ttgaatctgc taaaaaacaa ataaatgaca
    59041 ttttaactgc atttaaacat gagtttacta cttctgaccc tggcatgact tactcagtag
    59101 ctgaaacttc tgtagacaaa gttcttacta aagattgtaa agaaaaagtt gttcaaatgt
    59161 cttgcttaac tcctcatgga gttcaatcag taagtcttga tatagaagga ttagttgaaa
    59221 gttctactaa cttcgctata atcgaaacta aagaatctac tattgaattt ttaacttctg
    59281 ttagaagttc tgttatgtct attagagatg aaatcgctga tagaataaga cttttggctc
    59341 aagctttagg tgctaattac gaccttatag ctcaataccc agcttgggaa tttaaaaaag
    59401 gctcaaaatt agaaaaaata tgcagtgaaa cttatgagaa attaactggt aaagttccta
    59461 ctgttatggc tctacatgct ggtcttgagt gtggattatt acttgataaa cttcctcatg
    59521 ctgaagctat ctctatagga ccagatatgt ttgatgttca tactccaaat gaacatgtta
    59581 gtatcccttc tgtagctaat gtttgggatt atgttattga aatattaaaa tctatgaacc
    59641 aatattaaat ttaagttttg attctaatta gattttaatt ttaagtaatc tatataaaat
    59701 taactctgta aattaatact actgttagta taatatttac tttcaatatt aacttataga
    59761 aataaagcct aatgatagat aataacatgt atcattaggc tttattgtaa tttaaatatt
    59821 attaagcttt attctgtttt aaaattaatt cttatactat tttaaatcta tttcttcctt
    59881 gtctcttaga atcataaaga gcattatctg ctatttgata cagttcatca tactcttgac
    59941 caggctttgc tataactacc cccatactaa tagataaact ttctccattt ggcaacttaa
    60001 tgagatgaat atgattgtat acatcattac atttattaat aagttcttcc ttatttatta
    60061 tatcattgat ataaacacta aattcatctc cacccaaacg acctactata tcattttttg
    60121 caaaactttc atcaagtacc tttgcaacat caataagtac tttatctcct aacaagtgac
    60181 cataagtatc attaatcgac ttaaaataat caatatctat aatcaataaa gcaccatttt
    60241 tttcagttga taaattcaac aaattttgtg cagttaattt tctaatatat gctgcattat
    60301 aaatattggt taaactatcc ctttgagcct tatctaacaa tctattcttt tcctcttttt
    60361 cagaatcaat attacatatt ttcccgatta catacattgg tatttttcta tcattataaa
    60421 ttatttttga agtaactcta atccaatgaa aagtatcatc aagcataata gaatacattt
    60481 cagttgttcc attttcttgt gattttatta catcaaaaaa ctttttatta tattctttcc
    60541 ttattttatc tctttcattt tctatattgc cattttcact ttccttatca tttttatcca
    60601 aaccataata agtctcaata cccttttctg gcatagaaat tatcaattta tcttgcttat
    60661 aatcatactc aaaaaagtat tcacttgtca tttcatacaa ctgagtatgt tttttgagtt
    60721 ctaaagatat cttctcgttc atacttgtac gagtatgcaa accaaatgcc ataaatccaa
    60781 taatacaaat taataaactg gctacaataa aaatagtctc aattggattc tgttgcataa
    60841 tataaagcaa cgagaagtct tgtctatatg tagtattttg gtagacaatt gattgcattt
    60901 tttctgatga aatacttata atagctttat taaatatatt caataattct tgtttatctt
    60961 ttttaattat accaaaacaa atactctttg ctttataagt ttgaggaact agacgcacat
    61021 ttttatactt aggttgattc atatagtact gcatagaata accttcgcca taagtgtaat
    61081 ctgcatagcc tttattaaca gcttctatac actcttctaa attatcatac caaactatat
    61141 tctcttcaaa ctgaccataa taattaatac ctttggctag agctacacgt tttccatcta
    61201 aactattctc atttaattta ttattaatca tcatagtata ttgagtagaa agaaaaggcc
    61261 gagacataac tatattatgt tcacgagagt attcataatc ataaatcatt cctgctacaa
    61321 tatcaatttc acgcttttta gtcatgtttt ctaaatcttc ttgagatttt acaggcacaa
    61381 gttcaaattc taagcctgtt ttatcacata tatgatttaa caaatcaatt gatatacctc
    61441 ttaattcacc tgtatcttta tctatatttt gaaatggtgg tttgtttaaa agtactccta
    61501 cttttaattt ttctgtctct ttaatgtaat cagtttcttc atcagataaa aacatttgat
    61561 tgttctctgg tgtaaagtat ttttcatata aagtagttga aaaatatggg tctttctgtt
    61621 caatattatt aattgctgag ttaagctttt gagttaaatt tgtactacct ttaggagtaa
    61681 tgaaataaaa tggttttgat gaaaattttg ctacagtacg tacaccttct agtgggttca
    61741 tactcacatt aagaagtaca tctgctttac cactctttag tgcttctagt tgctcatcat
    61801 ttgttttaca atataccaat tcaggtgaca taagattcat cttacaatac tcatctaact
    61861 ctttaagcct agtatcagaa ttttctatta cagcaatacg gattttttca catcttgtga
    61921 actcattatg ttatcaatat ctgtattttc atataatgct tgtagtactg tatttgctac
    61981 tccataatta ttccctgcat aattatatat tttttgcatt ggctcattgt ataacatacc
    62041 tcccattata tcaatttcac cattttctaa catcttcatt aattttgtaa tagattcatt
    62101 tatatctcca ggaacttgaa caaattcata attccatcca gtatactgtg caatttctag
    62161 taaatattca tatgtatacc caaaatagtt accttgctca tctatttcag ttaaaccttt
    62221 ttgaatagga taagcaacac gaatggtacg attatcatta cctatagcgt tgataccaaa
    62281 agaaaatatg caagaagtga atatagatgt aattacaata attaataaaa gtaatttttt
    62341 taaattcact acacaatcct ccatatagtt aagatttaca gtataaatta ctgcataaac
    62401 ttgtagacat gtaaaaatag attagtatat aaaaggatat ataaatctac ttagaaattt
    62461 aaatatcctt aatatataca atatatttaa attataactc atttatatgt ctattacaac
    62521 aaatttaccc tgctaaatac ctactctata tcccataatt ttacaagttg tagtgaagtt
    62581 taagttctat ctcacctcaa atttagcagt gtttctattt acagttcttt tatatttcac
    62641 atctggataa cccaatataa atgaagtgat aacagcttcg ttctcgctca ttcctaacag
    62701 ttcttttatc tttggctcta catttgatgc cataacaaaa aatccattat aacaaattcc
    62761 taatccttga gaataggcca taagttccat attagatgca gccagtcctc catctacata
    62821 agcacttcca cctagagaca tatctcctac aactaccata agtagtgggg catcataaaa
    62881 taaagaatca tttccgttct ctttatatct tttgtacatt ttcttaaatg tatttttata
    62941 gatagaacgt acagggtcat tgtcatcagt atctaatgcc aaattataaa gaccttgtat
    63001 tgccagttct ttcacttctt ttagcttttc ttttactaat atgtatctta taggctgtct
    63061 attaccacct gttggtgtgt atctaccagc ttccactatg ttttttattt tttcttcttc
    63121 tacctctata tctttatatt gtcttatact tcttctaaat ttaataaaat tcaataactt
    63181 ttcgggttct aattcaaaac tttcacgatt gtattctatt acttcatttt tatcaaatcc
    63241 ttgcatttct attgcatctg ttgggcaaat tgccatacag tgaccacagt taatacagag
    63301 aatattttta acctttgctt tatcatcctt aacttttatt gcatttacaa gacagtctga
    63361 ttcacacata ccacagccta cacatttttc taaatttatg tctatcattc caaattattc
    63421 ctccttttaa aaaatttact ttagtataaa acaaatagtt gtctaagtca atttttattt
    63481 ttttaacaat atactagcct taactacact ttaatggaga aaaatataca taaattggaa
    63541 cttaaattag aacttattca aagtaaaaga taaaagaagt agatgtctaa aagtgaactt
    63601 tttagttaat tagatattct ttattgtatg aaatcaagtg gatatttatc atttcaacaa
    63661 taaaaaaggc ttacctctat tttggatatg tccctgtcaa gtagacagac taaaaaaagg
    63721 ctatctttat gcactgagat agcccctttt cccaactact attgtttatc ttaatattag
    63781 tcaataaatt taatttgcta taacctgtaa gttacatttt aatttgatgt aactttaaat
    63841 tacattttta agtaatatct ttaaattata ttcttaaaat atatcattaa actacatttt
    63901 aattaatcta aaaactatat cttaattaat ctaagaaact tacattataa tcttttagtt
    63961 tcccattatc atatacaatc tttgcactaa agatatttcc agtcttagcc caatttaaga
    64021 acagcctgtc accttcccac atatttaaat cgaatatttt atcattatca acccaaatta
    64081 aatttccttc tttacaatca tttaaatctt tttcagataa ttcaccttca aactcatctg
    64141 agaaatacaa aaacatatac caatcttctt catctttaaa ttttggaaaa gttatcaacc
    64201 ctttatatga caatgattta agagtaagac cagtctcttc ttttacttct ctaattacac
    64261 attcttctgg ggtctctcct tgttcaaact ttcctccaac tcctacatac ttaccttcat
    64321 gtatatcatc tttcttttta tttctgtaca acatcaaagt cttgtcatct ttttctatat
    64381 aacaaatagt tgtaagtttc atgtatctcg ccttgctttc tctttatatt ctcaactaat
    64441 tattttcagc actttcaagc acatcactta tattcttcat tgcattaaga gaaagctctg
    64501 caaattcatc aaatggaatc cctatatctt ctatacttct cattgcatct ctatttacat
    64561 ttgaagcaaa tctcgtttct ttcattcttt taataacaga cttagtcttt acactggtaa
    64621 gttttttatc tggataaact aaagctatag cagttataaa cccagttata gggtctgctg
    64681 catatattgc tttttccatt aggctagttc ttgtaactcc cattccatca tgatgaccaa
    64741 gtattgctct atacatttct tcgtcaccga agttttcttt tttaagcagt tctactgttg
    64801 ttgtagcatg tccttcacat atttctcctg gctttcttcc aactatatct gaatccaaat
    64861 catgtaaaag acctgccact gcccactctt cttctttttc tggctctagt cttttggcta
    64921 attctctcat aacagcttca acagcataac aatgttttct cattctatca gtttctaaat
    64981 acttaaataa aatttctaaa gcttcttctc tcattttcac caatccccct gttttttcac
    65041 atatatgata tttttatata ttaatacaca taaattcaag tttttatata tattcatgta
    65101 tatttttcat gttatatcta ttctacacct ttatagtagt gtcctgcaac tgttccaatt
    65161 tcatctaatt tcttatacaa gtctgtagcc ttttttccaa gtttataatt attactcaat
    65221 acctcaatgt gagcttcaat aaccttttta accatctcac tatcttcaac tgtaaaatct
    65281 atcctaaata catctattcc aatttcctct aactcatata gattgtccaa catacaagta
    65341 accttcgaat tgtaaattgt acttctacag aatatatctt gtgttatcct ataacttgca
    65401 tccgtaaagt ctcttaaagc ataactactt tccttacatt tagcaactct cttgtccttt
    65461 ttacaatctc taacaactac tcccatagga cagtattctg taaccatcat aggagcatat
    65521 ccatatatta ctgcttcaat ttctacatct gtatatttta aagtttgttt aatttcattt
    65581 aagtttagtt cttgtgacaa acaaactgta cttgctccct cttctttgaa gtggtttata
    65641 ctttcactat tgaatgcatt taagtagcaa tctatattta agtctttttt cttaaagtat
    65701 tccatagagc cccagttacc aatttgaacc ttattaattc cttttatatt atccaatatc
    65761 tcaaattgct tgtactcttt atttctaaca atccttggtg ctgaatagat taattttttg
    65821 ttagtgactg ctgtattata gtggttctta ttcaaagtat ctattttact tgtatttgac
    65881 aaagtatcta tgttatttgt atttgaaccc attagttctt taggagtatc taaagacgaa
    65941 gaagtatcta aatccataga aatacttgaa tctatagaaa tatttgaatc tatagaaata
    66001 cttgagacca tttgtaaagc ttttgataat gtatttatat cttcataata gattaaatct
    66061 acattataat ttaatactgc ttctaattgc tccaagttct taactttaac tctaatctta
    66121 ggaactgtat caagtttttt ctgtttattt actctatttg gctggtattt taatctattc
    66181 ttcttaaatt ttctatcttt tatctttatt ctttcttcat ctaaaagctc aatacaatcc
    66241 cttctcattt gatttaacac acttataggc atacttacac cttcatccag gtcaatttct
    66301 atctctttta acttatatgg tgtatttcca agcttttgaa tttgtgtttc tattttttct
    66361 ttacttaaag ccacctttat agctttttca actattttgt ctccttctac caccgattta
    66421 tttccacaaa aatcacttat aaaaagctct ggctttttac ctagtttaat actcactttt
    66481 gcacgtatat tagtttttat gaactcttta tcttgctgaa atgtagcttg tactctatcc
    66541 atcaattcgc tgtcagaagt cttatatata agctgatttc tctttgcttc tccaacaaaa
    66601 tctaattcta tcaaatcccc tttatgtgct attgtagtta tctctccatc ctttattatt
    66661 cttccaatag tacctccacc taagttaatt ccatcacctt tcttaagcgt attttctagc
    66721 attactctaa gtcttttgtt ctttctatta taatctaaaa cttttccaat atatagccct
    66781 tgattattag gtctattaga gttcattata tccttaccaa cttcacctaa tatatatcct
    66841 tttgtaaact ttctattaaa tatggtatac aaattattta ttatttcctc agaaatactt
    66901 atttttttct tatctacaaa ttcattaatc gcttctctat atcctgaaac cacagtagct
    66961 acatactctg gctttttcat tctaccttca atttttaaag ataatacacc tgcttcaatt
    67021 attttatcca aatcttctat agtacttaaa tctctaggac tcaacaaata atctccatta
    67081 ctttttacta cttctcctgt atttatatct atcaactcat acttttgtct acatggctgt
    67141 gcacacctac ctctatttcc agacctattg cctatcatac tactcataag gcattgaccc
    67201 gagtaacata cacataaagc cccatgtaca aaaacttcta tatctacagt tgtattttca
    67261 caaatccatt ttatctcatc aacatttaat tctcttgcta aaacaactct atcaaaccct
    67321 acactctgaa ggtattttac atcttctaag gaatgtgcta ccatttgagt gcttgcatgt
    67381 agttcaaagt caggtaatag tttttttata agtcttgcca ttcctatatc ctgtactatt
    67441 aaagcatcaa tatctatatc gtataaaaat tttacatact ctacaaaatc ttctatttca
    67501 tactgtttta tcaatgtatt tacagtaaca aagacttgca ctccccttat atgagagtat
    67561 ttaacagcct caatcagctc atttctatca aagttatttg cagatgctct agcactaaag
    67621 tctttaccac ctaaatacac agcatttgct ccgttttgaa ctgctgcttt taatgaatca
    67681 aaagagccta ctggtgcaag taattctatt tttttcatat ttttctcctc tatttatact
    67741 tgttaggtta atataattat atctataact taaatatttg tattaaattt atatatttct
    67801 tactatattt taaattcttc aatcaattta tatattagtt atttatattt ggttcatttg
    67861 agttaacata tacattattt actatattta gtatatttct attaacttat atatttatta
    67921 ctgtatttta aattcttcaa ttaatttata tactgcttac taaatttaaa acattttaat
    67981 taatttgtac actgtttact atacttgaaa tacttctatt aatctatata ttgcctacta
    68041 tacttaagac attttaatta atttatacac tgcttactat attttaaatt ctttaattaa
    68101 tctatacaat atttgctata tataaagtat atcaaataac agcttcattt ttttgtaaat
    68161 ttacagaaag ttaattttca ttaaatgaat catctttatt gataaacata attccaaaga
    68221 ccactgccaa aataaaaaaa catattagta ttgatttttc cacgaaaatt tttgtaaaaa
    68281 aagttcctaa aatagctcca gatataaaga atataataat agcataatac tgtaaactct
    68341 tttttatcat aaaaatattc ttagtatgta tataatgaaa taaagtttct gtagcacttc
    68401 ttaaatttcc agtacacatt gtcgttgcaa aactattccc atttactttt ctaaaactct
    68461 ctacttgcat tgaacaaata aaagaaatag caacatttac aaacatatta aatcttcctc
    68521 taggaataaa tgaaacaata agtattgtaa tcatttcaat tataatgata acctgacgcc
    68581 aatgaatctt tgtcttatta tttgtaaaat actttcttat cttctcggct ataaatacac
    68641 ctaacataaa tgccaaaata ggaatcaaat aataaaatga ttcctttaca ttaccttctg
    68701 ctatattaag cccaaacaaa actatatttc cagtttgtgc attagcaaag actttacctc
    68761 ttaccacata agtataaata tccaaaaatc ctcctgttat tgccaacaaa gaacataaaa
    68821 agaatgattc agacatctga ctcttgcttg tcatatataa acctctcgct ttctaatgat
    68881 agatacaaaa tcaaaatcat tttagattct atttttcatt gatataaaaa aattatttat
    68941 atttaaatat tgtctatatt tatacatcat ttatatttat ttatatttaa acattatcta
    69001 tatctatata gcatttatat ttatacatta aaagaagctg tctcaaaaaa caagagacag
    69061 caaatctttt agtttattcc acattttttg catcattatt taaccctgta cattttaact
    69121 gtaaatcata agctttgttt tgaaactcag aagctaagtt ttcagctata gtagctcttt
    69181 catttgcttc ttcaagttga gtacttaact cctcaatctt gtttttataa gcatctaact
    69241 ctgctctaga accttctgtc gtattactaa gttcgaatat ttcttgcttt ttattttcta
    69301 taatctcaat taactctttc atcttagttt cagcttcacg attttctgct tctttttctg
    69361 ctatcgtaag ctttaaagat ttgatttcta attgaagctc ttcattagat gctccaacct
    69421 tcttactcaa ttcttcattc gctttaatca acttctcatt ctcatctgaa cattcaaata
    69481 aaaggtctga tatatttaat gcagttaata tcgcagcaac tgataagctc aatttcgggt
    69541 tttgacgtgt tattttatcc atttctttgt ctacaaaatc agcaatacta atcataaact
    69601 tctctgattt gtctccaacc attggatatt cagcgccatg gattttaacc attactttgt
    69661 tcatcctaac ctcccccgac attagttgtt aatttgatct taagttagca tttaattttt
    69721 cgcttaattc acttaatatc ttatcatgca ccttagctac atcttcatct gttagagttt
    69781 tatctttact tctataagtt attgaatatg caattgactt gtatccagct tctatttgag
    69841 aacctttgta aacatcaaat aacttgtagc tttctactaa tccttgacca ttttccttta
    69901 ttatatcttc tatttgtttt acaaatacat catctttaac aataagagct atatctcttg
    69961 atgtagatgg atattttggt aatggcacat aattctttgt tctatcagaa ttatcaaata
    70021 caaagtcaat atctatttca gcgacataaa ctctttgacc tagattgtag ttttctataa
    70081 catctggatg caattcacct aatgtaccta catatttatt attatacact attttagcac
    70141 atctaccagg gtggaaggta gtattattat cttgaggttc aatttcataa cctttaaatc
    70201 cgacatttac aagtatagtt tctatagttc cttttagtgc aaagaagtca acatctttac
    70261 catacatacc tacacacatt ctattttctt ccttaggtaa ttctgaatct tgtgggatga
    70321 atatatgtcc acactcaaat gcagatactt cttctatttt atgagataca ttagttgata
    70381 aaacatctaa catatttggt attaaagtag ttctcattac agaagtttct tctcctaatg
    70441 ggttaagtaa tttaacaaaa tttctctttg cattaccttc tggtactctt atcttatcta
    70501 ctcccttagg gcttacaaat gaatatgtta atatttcatt taatcctaca gcagttgaat
    70561 tatcttttaa agcatccatg aatttttgtt ttgaagtttt aattcctgct gtcgtatttc
    70621 cttctaattg tacagaaggt atattctcaa atccataaat tctagctatt tcttcccata
    70681 catcagcttc ttgttccata tctgttctaa agcttggtac atctatttct aatttatcat
    70741 tagctaccaa attacattta aactctaatg attctaaaat tcctacaaac tgctccattg
    70801 gtacatctac acctaatagg tggttaattc tttgaggatt tactaccaat tttttaggtt
    70861 ctggtttatt tggatataca tctacaacac cttttaaaac ttttcctgct cctaacattt
    70921 caacaagttg tgcagctcta tttgctgcta tctctgcaag attagggtct aagtcttttt
    70981 catttcttga agatgcttct gacctaatac caactttttt agctgtcatt cttatgtttt
    71041 ctggtttgaa attggcactt tcaaaaagta cagtcttcgt attagaagtt atttctgagt
    71101 tagcaccacc cattacacca gctaaaccaa gtgatttttc tccatttgtt ataactagca
    71161 tatctttgtc taatgttctc tcaacatcat ctaatgttac aagtttctct ccatctttag
    71221 catttcttac tactattctt ccagtctcta cttgatttat atcaaaagca tgaagtggtt
    71281 gaccaagctc taacattacg aagtttgtta tatcgactat gttacttata ggtcttactc
    71341 ctgcttctgt aagtcttctt tgcatccaat atggagaagg ttctattttt acatctgtaa
    71401 ccattctagc aacatatctt ctacataaat ctggattatc tatctcaact ttgaaatcta
    71461 tctcttcgtc actttctttt acttcgattt caggatattt tacttttgtt cctatagttg
    71521 cagctgcttc tctagctata cccatcatgc atttacaatc aggtctgttt gaagttaatt
    71581 caaaatctat taaagcatct tttaatccta aaacatcttt tatatctttt cctaattcat
    71641 aagaatcttc gtggtctaaa atatatatac cacctctttt atactcctca atgtaatgtt
    71701 catctatacc tagttcagct gctgaacaca tcataccatc tgataattca cctctgaaat
    71761 cagtctgttt gatttcaact cctccaggta acttagaacc atttacagct actggaatat
    71821 aatctccttc tgatatattt gtagctcctg taactatttg aacaacttta tctccaatat
    71881 ctactttagt tacaaccaac ttatcagcat ttggatgttg ttttatttct aaaatctttc
    71941 caaccaatat attttctatt tcttcaccat aataatctat tgtttcaact ttagttcctg
    72001 tcattgtcat tttatcagcg aactctttta catccatgtc tatatcaaca tagtctctaa
    72061 gccattttaa agatactaac atctacatac cctcctaatt aaaattgatt taagaatctc
    72121 atatcatttt cgaataataa tctaatatca tctatttcgt atttaagcat tgcaagtctt
    72181 tcaaccccaa ctccaaatgc aaatccactg taaacttctg ggtctattcc acaatttcta
    72241 agcacatttg gatgaaccat acctgaacct aatatttcta tccaaccttc atatttacac
    72301 attgggcaac ctttaccacc acatttgaaa caagtaacat caacctctgc acttggttct
    72361 gtaaatggga agttgtgagg tctaaactta gttttgatat cagaaccaaa caatttttca
    72421 acgaagatat ccatagttcc tttaaattct gccatagtaa catcttttcc aacaacaagc
    72481 ccttctatct gatggaacat tggtgagtgt gtagcatctg gcgagtctga cctaaaacat
    72541 ctacctggtg caattacttt tattggtaac tcttgacttc tcatagttct tacttgaact
    72601 ggagatgttt gagttctaag taatacccca tcattgatat agaatgtatc gctcatatct
    72661 cttgatggat ggtctttagg agcgtttaat gcgtcaaagt tgttttcaac agtctcaact
    72721 tctggccctt ctgctataga gaatcccatt ccgataaata tatctgttac ttcatctata
    72781 atttgagtta ttggatgctt cttcccaacc tttaaaactt ttcctggttg agtaacatct
    72841 atcacttcct cttttaattt tctttctttt tcaatagcat ttatttcttc ttttttagaa
    72901 tttatgctaa gttcaatgtt ttctcttacc tcattggcaa ccttaccaac tactggtctt
    72961 tcttcagcag ataatttacc catttcttta agtatggcag ttatctcacc tttttttcct
    73021 aagtacttaa ctcttaaact ttctacactt tctatgcttt gtgcttcttt tatttcagac
    73081 aaagctgctt cacgtaaagc aagtaatttt tcttgcacac atatcaccct ttcgtttttt
    73141 tgtataaaaa aagcccctca atccctgtct agggacgaaa ggctatagtt tcgcggtacc
    73201 accctagtag tttaacaatt taaaaatcat caaaccacct ctaacaaact taacgcgttt
    73261 ttgacgtcaa agcctactgt aaaatttcag ctctgttact ccagagggaa cttctcatga
    73321 cctcttagaa aacactccca gcctaggtgt ttatctcttt actaagttta atcaaaatac
    73381 tttcctcttt cattgcattt acaatattat attgtttatt ttagtattat atcatttcca
    73441 ttcaaattat gtgactattt ttaatatata tccaatacat aattaattta attatttttt
    73501 atataatata tatctaatgc ataattaact caattatttt ttatataata tacacctaat
    73561 gcataattaa ctcaattatt ttttatataa tatacatcta atgcataatt aactcaatta
    73621 ttttttatat aatatacatc taatatataa ttaatttaat tattttttta atatatattg
    73681 actatttttg atactctact atttaattca agattataac atgacattat atttattaca
    73741 atacattaaa ttaagtattt ttttatttca tacatcagta tagcagagct tatcgcagca
    73801 tttaacgact cggctttacc atatataggt atcttaacca aaatatcaga ctttgataca
    73861 agttcttcat ttattccatt tgcttcgttt cctatcacca atgctacttt tgagccataa
    73921 tctattttgt cataaaaatt ttctgtattt aagtaacttg aaactatatt aaaatccaat
    73981 gatttaagca tgtccacagt ttcatcttgt gaagcatcaa ttatattcat atcaaaaata
    74041 gaacccatag tagacctaat tacttttggg ttgtatatat cgacacatcc ctttagtgct
    74101 attatggcat ctactccagc agaatcagca gtccttatta tagtccccat atttcctggg
    74161 tcttgtattc tgtctaaaat caatacaaat ttatcttttt tatttatact ttcacttaat
    74221 ttttttttct taaatgaaac tacacctatt attccttgag tattttctgt atccactaat
    74281 tctttaaagt ttttattagt agtcttgtat atctttgtgt tttttttatc caaatcttct
    74341 aatagtttta catgttcttt cttattttca aattcttcat tgataaatac ataatcaagg
    74401 tttgccatac attcaagtgc aagcattact attctgtatc cttctattat gaactttgac
    74461 tctttattcc tattctttga ttttaatagt gctcttgtat actttaactt ttcattatcc
    74521 ttactgttta tatttgtaat cattttatct aaatgctaat aacttataaa tttttatatt
    74581 agcacagcct ccttactttt aatttaactt ctctttatct aatcttacaa ataaatacta
    74641 ccttcgatta aaaaaatagt atcatataac tattcataat tatatgatac tatctacttt
    74701 cattgcaatt aaatatatat taaatagtaa attatcttct tctaattatc cccttatttc
    74761 cagatgttat cgctgttata ctagtatttt gaccgattat aactaggata cttccggctg
    74821 taagttcctc atctggagaa ggtgtaacat ttatattttt acctgttttt atagcaagta
    74881 cagttatctc atatctagct cttaattcaa gctctataag tgtcttgcca acccaactat
    74941 ttggagttac gatttcaaca attgaatact ctgggtcaag ttcaatatgg tctaatatat
    75001 tatccgaaac taaattgtgt gcaactctta ctcccatatc tctttctgga aatacaactc
    75061 tatctgcacc aattttataa agaactttag cttgtaattc atcctttgcc ttacatatta
    75121 tcaactctac acccatttct ttggctataa gagtcgccat tatagatgcc cttatatcag
    75181 aacctattgc aactactgct acatcaaagt tacctaaacc taatgacctt aacgcttgct
    75241 catcagtaac atccactata agtgaatggg ttaccttgtc agatatactt tgaactgaat
    75301 cttcattttt gtctattgcc attacttgat gtcctaaaag atgcatagta gacgcaactg
    75361 aacttccaaa tctcccacac ccaatgacta tatattgctt catctcgaaa cttcctccct
    75421 aatacacaat ttatataata tctcttaaat taattgttta cacatacaaa acttatatac
    75481 tttacacata caaaacttat acacaatata taattttata cacacagatt aatttaattt
    75541 tgatttacct ttttatttgt attttatttc cctgtttttt tatttcatta attaattttg
    75601 ttcattagtt gattttattt cttcatataa ttacatctag gctcatttat tttatcaaca
    75661 gatttacagt gctactctaa acccattata aatttatact actccttggt aacttaacca
    75721 accataattt taccttctgc atatctgatt ggttgactct ttcttctacc accagaaagt
    75781 atagccataa ataaagtaag agaaccaact ctacccataa acataaagat tattattata
    75841 atcttaccta aagcatttaa gtttggagtt ccagctaaac ttgaaccaac tgtagcaagt
    75901 gctgatgtaa cctcaaaagc tgattgaact aatgtaaaat taggctgagt tattgaaata
    75961 atcaatgttc caaaaataac tgctgatata ctgattacaa atataccaag agattttttt
    76021 atagttgatg gagctaatct tctttcaaaa gcttctatat ctgattttcc tgatagaaaa
    76081 cttctaactg taatgattaa aacagctagt gttgttgttt ttataccccc accagttgat
    76141 gcaggtgatg ctccaataaa catcaaaatt atcattacaa atacactact ttctcgtaaa
    76201 gtagctaaat caagcgtatt aaaaccagca gttcttgctg ttactgattg aaatattgct
    76261 gatagtactt ttccctttaa aggcaagtcc gccatagtag ctttttgatt aaattctata
    76321 agaaaaataa ataatgcacc cacaaaaata agtgtagcag ttgaaaacaa tacaacctta
    76381 gaatgcacat ttaattttga aaatcttctt tttcttacaa tatcaagtac aacagggaat
    76441 cctagccctc caagcactat aagtgcgcaa acagtcattg atactgtaaa gttgtttaca
    76501 taagaattta acgatgtaaa tgggccactt acactgccca tcaagtcaaa tccggcatta
    76561 caaaacgctg atattgcgtg aaatacacta taccatatcc ctttagacaa accaaattgt
    76621 ggaataaaga cagttgataa aaccagtgca cctattccct ctattgttat ggttattatt
    76681 aatacaaatc ttgtaagtct tacaagtccc gataaatcag cttgatttaa tgactcttgt
    76741 attaataatc tttctcttag ttgtattttt tttcgtgcca taagtgaaaa cattgtggct
    76801 acggtcataa atccaagacc accaatttgt atcaatgtta ttataactat ctgtccaaat
    76861 aaactccaat aagttgctgt atctaccata actagaccag taacacaaac cgctgaagta
    76921 gccgtaaata gagcatttaa taagcctata ctctctccac tctgcgacgc tatcgggagt
    76981 gttaacaaca atgctccgat tacaataatc gcagcaaacc cagataccat tatttgagta
    77041 ggacgcattc catctgcgta gagaataagt cttctaacta ttgttttcaa ctttctttat
    77101 acctccttaa cataaaatca ctactgttaa gacccttaat ttgtttattt ttagagcttt
    77161 cctctaaatt attattctat tatagtataa atattgtata aagacaatga tagtaatttt
    77221 tataatttct gtttggaata ttttaaattt ttatatatat cttttaattt aaattgcacc
    77281 aaaaacatct atatttttta catataatag gtctaaaact atcatagctt ttactatttt
    77341 gtacttaaaa tttatttatc attttaccag tataaatttc atatactttt ttgaagttaa
    77401 attttttata ttatttataa tcttatctat atctttatgt taaattttct taacatgcat
    77461 tttttatatt taatatagta aaataattaa taactatatc catgattgga ggatttttat
    77521 ggttaaatcc aagaagaaaa tatttgtttt tctaatttta attgcagttt ttattatatt
    77581 tgcatcatac ataagaaatt atactaatga tacaaaaaaa gattctgtta gaggaactat
    77641 tccttttgaa aaaatggaat ataagcgtcc taatatacag tcaatttgcg aaaacattaa
    77701 caagtgcaac gacaaacttt taacagctaa aacagctaag gaacaattaa atttatttaa
    77761 tgaagttgat aaaatttatc aagattttta cagtacactt actatagcaa aaattagaaa
    77821 taacatagat tcatcagacg aattttactc taaggaatat aagtatctta tgagtaaatc
    77881 agtagatgtt gacatgtcat acaaagactt tcaagataga tttgtaactt ctaaattctc
    77941 taaagaatta gaaaaagaac ttggaaagga tacatttaat tatctaaaga acattggaaa
    78001 acttaattct aaagaagttg aaggtttgct taaaaaagag caagacctag ttgtaaaata
    78061 tgaagactta ttagctaaat ctacagtatc aatagatggt atagaggtag actttgaaga
    78121 agccttgtca agaccaaatc ttagccctga agaatatgtg aaaatttatt cagattactt
    78181 aaaaaaatac aatcctatat ttggtaacat attcttagaa cttatacaga caagaactga
    78241 aatagcaagt aagcaaggat ttaagaatta tatagattat gcctatatga acctaaacaa
    78301 agactattct caagaagaag ctaaaaaatt tagacaagat gtaaaagatt acatagttcc
    78361 attatataga gagatttcat ctaaaccatc tgattcttct atttatatta aagtatataa
    78421 aaatcgctca tttaggaagt ttgataaagt acttgaagat atatctccaa aactaaaaga
    78481 gagcttcgac tatatgaaaa aatatgactt gtacgattat tcttctggaa aaaacaaatc
    78541 acctggagga tatactactt atataaataa atataaagca cctttcttgt ttaatacatg
    78601 ggataattct tttttaggtg ttactagttt tgctcatgag tttggtcatt tttataatta
    78661 ctacaacagt attaacttaa acaataagat gcaaccaagt atagatgtat gtgaagttca
    78721 ttcaacatct ttagaaattc tattttataa atattttgat gatttttttg gtaaacaatc
    78781 tgaagctata aaaaaagaac acttatcgat tgttttaaat actattattg atgcttgtct
    78841 ttatgatgaa tttcaagaaa ttatatacaa gaatccatat atgagtctaa atgatatcaa
    78901 taaattgttt tttgatttag aggaagaata tggagtttcc aataatatac ttagagaaaa
    78961 aaatgctcct ttttggatac ttgtatctca taacttccaa gttccttttt attacttgag
    79021 ttatggtctt gcatctgatg tatcacttca gatatggcaa ttatcacaag aagattacag
    79081 aaaagctgtt gatgtatata tggatttttt aaatcaaaat actgatgctg gatttaaaga
    79141 tgtggtagaa aaggtaaatt tacaattacc tttccaagat ggaaatttag aggaaataag
    79201 ctctacttta tatgattatt ttggtataga taatccgctt gaactaaaaa atgcttctta
    79261 atttctaata ctttatactc actcttaaga tttagtatta gattgaaata agtgatattt
    79321 tttcacacac aattaatgtt taataaaatt atatggtaaa
//
LOCUS       DAFAZV010000017        76159 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFAZV010000017 DAFAZV010000000
VERSION     DAFAZV010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 76159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76159
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.017"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..954)
                     /locus_tag="KOU88_001668"
     CDS             complement(<1..954)
                     /locus_tag="KOU88_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3211563.1"
                     /translation="MEEIDDTILDSMFKLTLNERLLTNNDFIENKIDVVKNLIDCYKT
                     EQNSLMLLKSNFLLALLYGIQGFSEKMKEYILISCKYIDKCLPKDYKFLARFYSQIAI
                     LSLKNEDVNKANLYMDKFNLICDENNFLIEEIIFKSQLIYIKASKCIESSVIIKEIET
                     LYIKIKEINDFNCKKIYFFIIGKIYFLFLDDALIAKVNFLKARKYADLLKDMQVSSLC
                     NIKIGECECSFENYECSMEYFNEVISNKKYRNVNIIQKYRASNNITKILIKTRNYPVA
                     INNLAKSEVYLEKIKNHSLKEVEKFDLFISLAMYYAKSNEKS"
     gene            complement(1085..1504)
                     /locus_tag="KOU88_001669"
     CDS             complement(1085..1504)
                     /locus_tag="KOU88_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3785 domain-containing protein"
                     /protein_id="HBK3211564.1"
                     /translation="MSLYKFIYDDKEYLLKEENCSALINDEENPVQGVSISKIIDILN
                     EAEEVDFDVEYYQEACPLCLEGVKEKKKFFPFLEYHFYIFSKDGEYVISNISVDYKGL
                     SFNKLSRANKVDNSYIVSVIICENCQDYIVQIENCIV"
     gene            1817..1999
                     /locus_tag="KOU88_001670"
     CDS             1817..1999
                     /locus_tag="KOU88_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211565.1"
                     /translation="MYKDKSDECIHLMTAYIDSISGYYSFIDTQLEDFMMKYGENIVD
                     SNLHSIMMLLCKWGLS"
     gene            2328..3350
                     /locus_tag="KOU88_001671"
     CDS             2328..3350
                     /locus_tag="KOU88_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBK3211566.1"
                     /translation="MNYNDLLKSARENFNGTCKVCKICNGLACAGDVPGMGGKGSGSS
                     FIENRKSLEKIKINMRVIHNVSKPDTSIELFGRKMSSPIFAAPVSGTILNMGGKVSEK
                     EYIEPVVRGCSNSGIYAMVGDTNVDTFLLDNLDVLKDNRGNGIVFIKPWNNSKIIEKI
                     RLSEEAGAFAVGVDLDACGLINNQFQENPFSPKTIDEIRELVESTRLPFIIKGIMTVD
                     DALMAVESGASAIIVSNHGGRVLDYTPGTCEVLPAIAKSVKGKITILVDGGVRTGVDV
                     VKMLGLGADAVLMGRPFVTASFGGGLDGVEFFIEKVRNELCETMILTGCQNVKDIDGR
                     VIWNLL"
     gene            complement(3620..4733)
                     /locus_tag="KOU88_001672"
                     /pseudo
     CDS             complement(3620..4733)
                     /locus_tag="KOU88_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816433.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            complement(4871..5470)
                     /locus_tag="KOU88_001673"
     CDS             complement(4871..5470)
                     /locus_tag="KOU88_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-binding protein"
                     /protein_id="HBK3211567.1"
                     /translation="MLKKSKKTLAIMCCLMLTFTSVAFADASKGEGVSKEAVSEKNTY
                     SFNISGYVYTYENAPQKIRDEHKQNCEDVNIAPKPDDKIFVPTSANLMNDDDKAVYTN
                     YAVAYKPDEKTITVIGGGEFITISTTKVIRKGDTGKEVTVAQIMLSKLGYNTSPDGIF
                     GSKTYNAVVSVQKKYGLSADGVIGPATWDKLGRLTDSSF"
     gene            complement(5487..6635)
                     /locus_tag="KOU88_001674"
     CDS             complement(5487..6635)
                     /locus_tag="KOU88_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="HBK3211568.1"
                     /translation="MNNYMLYVFENLIKTTIVCSLGICLLLFLKRYLFKKFSKRFNYY
                     IWLIIVFRMLLFLFNYTIVYEVKEPKENALGNNITQIDISTDNNLMLYVAYLWLFVTI
                     VIAVYTFIKYTRFKNLVVDVSYDIEDNDINCIYKNLLKELNIKKKIELRGSDELISPA
                     GMGLFKSYIFLPDYPYSKDELTWILKHELMHFKNKDILIKFLVLSVRIIYWFNPLVYV
                     MSNKVNLDCELCCDESVLTDCSLKDKKEYALALIKSIKLSKNYNSGILTTEFNKTNLE
                     KRLESIVKKKGRSGILIAILVIMTSITSFIEVDAQIKINNSINEINNNINDFILNKST
                     DKHQTFYYKDAPSKIRKFYEDNCKLKGTTPKDYDTIIINTKDFNELMK"
     gene            complement(6628..7005)
                     /locus_tag="KOU88_001675"
     CDS             complement(6628..7005)
                     /locus_tag="KOU88_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3211569.1"
                     /translation="MMIRKIPQAELKVMKFIWKVDVTVTSKDVIEAMEQKYGWKQTTT
                     LTLLSRLVKRGFLDAQKIDRYTHYTIRVKHKDYLSFETKDFLSNIHDDSLRSLISALH
                     DDENIGKDKLDFLESYFDNLKDE"
     gene            complement(7643..8122)
                     /locus_tag="KOU88_001676"
     CDS             complement(7643..8122)
                     /locus_tag="KOU88_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBK3211570.1"
                     /translation="MSNKLIKNLLSGILQILFFLLGLVIVAGGFKSFMYLCFSGEATL
                     QGTIYGILMFILGVSYFIIIKSLIEVLGSSEYSLFVKENVKRFRIIGYLLLLNSLIEF
                     ISTFGTTGKGMRFLDLGFGFYFTVPVFVYFITSLMSFVIADGFVKAIKIKEDNDLTI"
     gene            complement(8417..9121)
                     /locus_tag="KOU88_001677"
     CDS             complement(8417..9121)
                     /locus_tag="KOU88_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B3/4 domain-containing protein"
                     /protein_id="HBK3211571.1"
                     /translation="MKKFVIEDAFWNLFPSAKIGVVICNDIDNSIKDEDYKKIILKGE
                     EEALKYLEDSEFSNNQVIKVWREAFKKFKTKKGARSSIEALLKRVHNGNNIGTINPLV
                     DIYNFISLKYALPCGGEDIDKFIGDIRLTRAIGNEEFIPLGTDENSFPYEGEIIYKDD
                     VGAICRCWNWREAVRTMLTEDTNNAFLCIELVDESRFKEFENALNELAKIVQEKLGGN
                     CKISILDIDNKEVSVD"
     gene            complement(9475..10491)
                     /locus_tag="KOU88_001678"
     CDS             complement(9475..10491)
                     /locus_tag="KOU88_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBK3211572.1"
                     /translation="MGYYNDNDNNKIRRKKISNNKDSNKKSKHSYTSANKKNKSPNTS
                     SSKRMSEKVDSQNLIKRDRDSFTRDNVRPLNTDYNQRERRRVEYKQREKKLKSKKRKK
                     QKRIRIVRALLSIMLVALIIFSVAGAIFTVSAIKGSPEVTKKLIRSKYISSEVVSIKQ
                     MPNDLKHAIVSIEDERFYKHKGVDVISLVRSVLNNVFTDTTQGASTIDMQVSKNLLTS
                     NDKTMKRKIRDMYNAKQMNKIMTKDEILEAYLNNMYLGKNAYGAAKGAEVYFGKKVSE
                     LNLAECAMLAGMTNNPARYIDHGEAKKRQVIVLYKMHQLGYITDKEYRIAKADDTPFK
                     SEID"
     gene            complement(10619..11125)
                     /locus_tag="KOU88_001679"
     CDS             complement(10619..11125)
                     /locus_tag="KOU88_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HBK3211573.1"
                     /translation="MKEYVVVDLETTGLDPYKGCEIIEIGITEIKNEQIVKNYSRLIK
                     PKGIISSFITELTHISNEMVENEEPLELVLPRFRKYIGDRTIIAHNAKFDLKFLNYYL
                     RMLDLEPINNYICTVELLKKCKSYKGKNKKLETACAYYNIENINAHRADSDTLATAKL
                     FLKIKDEY"
     gene            complement(11284..11952)
                     /locus_tag="KOU88_001680"
     CDS             complement(11284..11952)
                     /locus_tag="KOU88_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211574.1"
                     /translation="MENITSYFTTILCVFICLSSVFIFTQLARVFINKKKINQKIKSR
                     NGFRYDRDFIEARREEIHIKDNNNNKNKSNNKKLKEEKVFKYDNGDLYKGEFVDGKKN
                     GFGIYIFSSKEKYEGLWKDDKMHGIGKYTYRDGSIYTGEFKYGLKNGLGKLTYPNNDI
                     YKGYFLDNKKNGKGVLYKNDGNKQAGIWEDDEQCKSLDFKDLNNNKINNVYQNRLNNN
                     KLKV"
     gene            complement(12365..12871)
                     /locus_tag="KOU88_001681"
     CDS             complement(12365..12871)
                     /locus_tag="KOU88_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HBK3211575.1"
                     /translation="MGFREVKIEELQFNPFTKIGKEWLLITAGDSEKFNTMTASWGGV
                     GVYWGKNVVTTYIRPQRYTKEFVDSNDTFTVAFFDETYREALNICGTISGRDINKIEK
                     AGLTPYFVDDTVAFEEANMIIVCKKLYHDNMPPENFDAKENDKKWYPEKDYHTMYISE
                     IIKVLVKE"
     gene            complement(13242..14270)
                     /locus_tag="KOU88_001682"
     CDS             complement(13242..14270)
                     /locus_tag="KOU88_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBK3211576.1"
                     /translation="MKRVYIDFEMNMPNSKSKRAVFNSDIIAIGAVMYDEKTKNIDKF
                     KSLIRPVSNEELYPHIQELTHISSEELKSAPSYEEVMRKFKKWLGIFSDIKGIYTFGN
                     LDLTCFNNTDMRSAKKNNHPRFVNNIRDLFVDIKEKYINCGMRCMNYISLKNLLEFVN
                     LEFSGDAHDPLNDAYNLFILDEAITNNVDIQNLLIIRDIIRPPFNDINSNLDNCFNKF
                     KESLYKKEGNYNIVDFSVEIIKTVRMYLLTIIDVNIQNLEIMKDISKKMDTIDKLKDI
                     EEGYFYLLEDVYFDMKDVLEDLMLYRMNEDEYKYEIKNIIKMFDEDLDNEKIYINKCN
                     NLNVVNKI"
     gene            complement(14318..15178)
                     /locus_tag="KOU88_001683"
     CDS             complement(14318..15178)
                     /locus_tag="KOU88_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBK3211577.1"
                     /translation="MSELSGKGCEIIVPFEERLPVRDIEKSIIKKYRKNLWSKFMKAI
                     RDYKLVEEGDKIAVAISGGKDSILMAKMFQELKKHGQVNFDVEFIAMDPGYHANIRQL
                     LIDNCEYLNIPIHLFDSRIFEIADEIAKDYPCYMCARMRRGALYSKAEELGCNKLALG
                     HHYDDVIETTMLNLLCAGNFKTMLPKLNSTNFEGIKIIRPLYYIREEHIIRFIQNSGI
                     WPLNCACMVAAKKTGNKRYEIKDLIKSLESNFKNVEKSIFKAAENVNLDSVLGWQKDG
                     EKHSFLENFE"
     gene            15447..15656
                     /locus_tag="KOU88_001684"
     CDS             15447..15656
                     /locus_tag="KOU88_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBK3211578.1"
                     /translation="MENKTRDIKKNCGPSLARPYINNQIFTEMYCLSDALKFGTIFPE
                     LNLLESEMYNKELYAKPKKYRGGRR"
     gene            15656..15922
                     /locus_tag="KOU88_001685"
     CDS             15656..15922
                     /locus_tag="KOU88_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBK3211579.1"
                     /translation="MKDSSRAELMRKVQETSFACVDMNLYLDNHPDDKNAINTYNSLC
                     NQFAQARYAYENKYGPLTNFGYAPSRCPWQWADQPWPWDREFNY"
     gene            15951..16523
                     /locus_tag="KOU88_001686"
     CDS             15951..16523
                     /locus_tag="KOU88_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBK3211580.1"
                     /translation="MWIYQKTIQHPVNIKTCDPRMAKFLITQFGGPNGELAASLRYLS
                     QRYTMPTGNMRALLTDIGTEELAHVELICTMVYQLTSDASPEELKAAGLGSNYAQNGY
                     GIYPTDSNGVPFDVRPIAVMSNPVTDLHEDMAAEQKALATYYQLINLTDDVDVIDVLK
                     FLGQREIIHYQRFGEALMDAYELEESQKMF"
     gene            complement(16758..17948)
                     /locus_tag="KOU88_001687"
     CDS             complement(16758..17948)
                     /locus_tag="KOU88_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBK3211581.1"
                     /translation="MNFNQKRIAASIMATAIIMPTMGNLAYANESEVESVSIESRTIT
                     GNAVNFRKGPGTNHESMGKLYKGDKVEYVGKEGSWVKVKYNGNTGYVHGNYVAINSLG
                     SSNESSDTSVKSTKVVTAKGLNFRTGPSTSSSKISTLGYGTEVGYISESNGWSKISSN
                     GRVGYVSSKYLGTSVNDSTNENAENSSNDLVKGTKVVTAKSLNVRTGPGTSHSKIATL
                     SYGTEVGSISESGGWTKVSYGNQTGYVSSQYLAEKGSVDTSIPSYSTNSPSQGADSVI
                     SFAKTLLGKPYVWGAEGPNSFDCSGFTQYVMKKSVGVSIPRVSRDQSKYGTYVNRGDL
                     RSGDLVFFDTQGSNNGSVSHVGIYIGNGDMIHASSGSSKKVTISNINSSYYSSRYVNA
                     RRVL"
     gene            complement(18208..18639)
                     /gene="dut"
                     /locus_tag="KOU88_001688"
     CDS             complement(18208..18639)
                     /gene="dut"
                     /locus_tag="KOU88_001688"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBK3211582.1"
                     /translation="MYNLKVKKLNDDAIIPNFAHKGDAGMDLYSIEEVVIPPGETKLI
                     KTGICIELPTMTEAQVRPRSGLALKHSVTVLNTPGTIDEGYRGELKIILINHGKNDFK
                     VEKHMKIAQMIVKPIYDINIEEVKELSDSERGKGGFGSTGF"
     gene            18752..20980
                     /locus_tag="KOU88_001689"
     CDS             18752..20980
                     /locus_tag="KOU88_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBK3211583.1"
                     /translation="MKLVLAEKPSVAKTIASFLGAKTRQDGYFEGNDYIITYAVGHLV
                     SLYDMKDYDKDKYSGSWKMNNFPFVPEDKFKFKIDSSKTKQFNTVKKLLNRKDVEYVI
                     NATDNDREGELIAFLIFLLAKNKKPVKRILVNEWTPEDITRGIKNLKDEDEMRNLQAA
                     GYTRLITDWLIGINFTSVATLKYGNGKLLNIGRVILPTVKLVYDRDMEILNFVPKTYY
                     EIEGHFKAEAGEYKGKFVKGKESKFDKLEDANKIIASITSETGKILDKKVTMSKEYAP
                     KLFSLTSLQGYITSKYSNFTSDKVLNVCQSLYEGNGKGGYITYPRTDSIFLEESLASK
                     ASQTLDKLKVGLEYENKIKFSKTKRVFDSSKVDSHSAIIPTYIIPKSLSKDEQLVYDA
                     IKDRFVANFMPPAEYENTEIKTEVDNCTFLTKGKVLKSKGYLEVYNKEEKNDLLPLVN
                     KDDVVDVLEIKPLTKQTTPPKPYTEDTLLKAMKNCGKNVPEEDTTVLSGYSIGTSATR
                     ADVLKKISQVGYVKKKGKSYSITDLGKNLVEIFPVKDLFDVDYTGKLEKSLSDIQKGK
                     YTRKEYLTNIISFIYQNVNIIKQDASKNINTEAYTFDSKTKKFTKTKEKKQKKDVTNT
                     EKEVAISKDSNNKKEVKNGDENQSLGKCPICQGDVLEFDKGFACKNHKECKFVIWKND
                     KYLSLYKKKVNKTMVKNILKKGETKVKSLTAKNGNKFDATLKYDKNPDTGYFNWKIEF
                     DN"
     gene            complement(21091..21576)
                     /locus_tag="KOU88_001690"
     CDS             complement(21091..21576)
                     /locus_tag="KOU88_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3211584.1"
                     /translation="MDNNNILKIADSFLDFLFVLENNIFKESDLLKKFQNNSDIMKAY
                     FEECPMAPSHAKVILYLMTSNSSSISQIASNLGILKSNMTPIIDRLVEHGLVNKFPDP
                     KDRRILRVELTDKAFKLFDAVKAILKESLVKKLSNLSEEELTLLDEHTLKLSEIVKKL
                     G"
     gene            21828..23051
                     /locus_tag="KOU88_001691"
     CDS             21828..23051
                     /locus_tag="KOU88_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBK3211585.1"
                     /translation="MKRYLIVFLMCSSLFLVGCGKTEESEPEKPIAVSVQKAIGGEIE
                     NTNSFSGTTKVKDETAVTAQTVGTVQEVYVKLGQNVRKGDELLSISSPELENSVKQSK
                     ASLDLAKASYSSATGGSLEAQVNQAKTALDNAKIQYEESQRNYDNNKILYEQEVISLD
                     QFKKIEFSLEQTKQQLDSAQRAYDTATSKSIPQAKALAKKQLDQAQVSYNLAMSNLDK
                     LTLTSPVDGTITAKNFDSKEMITQSQPAFIISNPNILEVDLNVAESDIGKFKKDGNVD
                     VIIEDQRILGKIDYVPSVVDPQTSLYPVKVLVNNTNNKFKAGMSAQVNLSVEKENGAV
                     TVPKKAIFEENGKKYVYIATKDNIAKKHLVQTGIVTEDKIEIKSGVSDKDTVIIGGIS
                     LISDGTKIFPVEKEK"
     gene            23055..26189
                     /locus_tag="KOU88_001692"
     CDS             23055..26189
                     /locus_tag="KOU88_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HBK3211586.1"
                     /translation="MNLTQTSVKRPLTIIMVFLVLIVFGGIGYKKMSINLMPDIEIPV
                     VMVMTTWTGAGPQDVDEQVSQKVDESLSAVSNVKSTISSSQESVSMVVAQFEFGTNLD
                     EIMNDVRSKVDALQTSLPDDAAKPTVLKLDMNAQAIGQLVISGGNENSSQALRKYAED
                     VIQPKIESIDGVTSADLKGGKKAQVNVIADPAVLSNYGVSLSTIKGVLSSSNKTFPYG
                     SITQGEDKIVLRAIDKLESLDDIKQIQIPVKGGNTVRLDNLCSVDYGYADKDSIYRYN
                     GKDSLVIDISKQQDANTVKVMQSAYKYVDELNKENPQFKIKIANDTSSYISESINSVM
                     SNLLISAVIAFIVIFAFLKSVRASLVVAVAIPISIIGAIAILYFTGESLNLITASSLV
                     ISVGMVVDNATVVIENIFKYRKSGRLSLDDCAIEGTRTVTNAILASTLTTIAIFLPIM
                     FTEGIAKITFGALGKTLIASLAFSFIGAITLVPSVFAKLSRGKNSQKMQEKDSPIFDK
                     VSEAYKKLLSVCLRHQRLVVISSLLIFVASLFGMGFIGMDFMPAADKGELSISIELPK
                     GLSLESNDYYVSMTEKKVSDIPEIKTLITTLTSDSNNSKASIAIELESQKNRKRTTDE
                     IEKEIIDRVATVPDCKINVSQNSSVMGGAGGADFTLEMKGPDLDVLKILGKEAEKEFS
                     SIKGFRNVETSLTDTTQEAQFTIDKHKAQEYGVNTAEIAGMLRTAINGDSVTTATIDD
                     YKVDVNLKFKADTIDSLEDIKQLKVNSATGKEVPLGAFSDIKMADGLQSISRTDGDFS
                     VNITATLDNLDAGTATKLALEKTNKMVIPKDYSIGVGGETEMMNESMASLGFSMVIAI
                     ALVYMVMVAQFESFSKPFIIMFCVPFAFVGVVLSLLVSGQSLSTVGMLGIILLIGIVV
                     NNGIVLIDYIEQLRKTNRNNDLIGLVSIGCAARLRPVLMTTATTILGMLPTALSLGEG
                     GETMQPLAIVIMGGLTVSTLITLVLIPTIYLIFDKWENKFSDKMPKIFGKITDKIGSI
                     KRKIIKKPKLKAKV"
     gene            26223..27521
                     /locus_tag="KOU88_001693"
     CDS             26223..27521
                     /locus_tag="KOU88_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBK3211587.1"
                     /translation="MSKIVAIGCGVGIITANLIPVYADNNTSSINKVDNSILSDSNKR
                     TSEKEILTAREAVSAALKNSEKLKMKSEEIKMLKEKLEVQDEFDSFTGSDNSFPYDQI
                     GLLKNQSEQAKGFMEDQIANDITNKFNDLVSRENELDKIKNNLEIKTKEIKDMKLKKD
                     LGLVTSLETESAELELQTLQNTQKAKLQELKNNQDYFKLLTNIDLNNYQLDKEYRFES
                     FRVGGSVDSYMEGKVNEYLKYDQLILERTEESFNDKDENKADLPDRPNLTRPVAPTKP
                     EQGNLTDDEYKVLTDKYEKDYKRYEKEVEAYNLERQTYAAGLTTYANYLQQKFNTENG
                     LVTLEDSKKALKKGLIDSYAQLLALEDTIQITKKQLDLSEKQLKNTKLRYDLGLIALT
                     DYKKQVVSNQDAKNSYDTLIVNYNSLKNGIEKPWILNTGK"
     gene            complement(27810..28055)
                     /locus_tag="KOU88_001694"
     CDS             complement(27810..28055)
                     /locus_tag="KOU88_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK3211588.1"
                     /translation="MTKCPKCGKEVSSRPGSICPRCGFKVADESLKIRCPEPSCRALV
                     SRKLDYCPKCGCKLRGYNISEFVNMVRCKIDETFDKK"
     gene            complement(28269..30896)
                     /locus_tag="KOU88_001695"
     CDS             complement(28269..30896)
                     /locus_tag="KOU88_001695"
                     /EC_number="2.7.9.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBK3211589.1"
                     /translation="METKYVYSFGEGSKDMKSLLGGKGANLAEMTKIGLPVPPGFTIT
                     TEACNDYYVNNESIRAEIIKEIEEHLATLEKDLNKTLGCNKNPLLVSVRSGAVFSMPG
                     MMDTILNLGLNDNSVVGLAEATQNERFAYDSYRRFIQMFSDVAMEVPKYKFENVLDRV
                     KEAKGYTVDTELTTDDLKEIVKEFKAIYKKEIKNDFPQDPKEQLMLAIEAVFRSWNNP
                     RAIVYRKLNDIAHNLGTAVNIQSMVFGNMGETSGTGVAFTRNPATGENKLFGEFLMNA
                     QGEDVVAGIRTPQNISTLADVMPAVFDEFVKITHILEGHYKDMQDIEFTIENERLYIL
                     QTRNGKRTAAAAINVAVDLVEAGIIDEKEAIMRIEPNQLDQLLHPKFEDKALKEAKVI
                     AKGLPASPGAASGKVYFNADDVVKANEKGEKVVLVRLETSPEDIEGMVKAEGILTARG
                     GMTSHAAVVARGMGKCCVAGCGEIKVDEFNKEIRALDDVVIKEGEYISIDGSTGNVYL
                     GNVKKTEVSLTGNFEKLMNWVDKHKCMMVRTNADNPRDARAAIEFGAEGIGLCRTEHM
                     FFDEARLPAVREMILSNTVEQREKALEKILPMQREDFVELFKVMDGKPVNIRLLDPPL
                     HEFLPHDDETIEELSKSMGIKVSDIKKRIVDLDEFNPMLGHRGCRLAITYPEICVMQS
                     KAIIQGAIEAIKAGVKVSPEIMVPLVGEVNELKIIRKMIVETVDAIIKEEGIEVPYTV
                     GTMIEIPRACLTADEIAQEADFFSFGTNDLTQMAFGYSRDDAGKFLGQYVDEEILEKD
                     PFQVLDQNGVGKLVKMGAKLGREVKPELKLGICGEHGGEPSSVEFCYSVGLNYVSCSP
                     FRVPIARLAAAQASIKNPR"
     gene            complement(30957..31799)
                     /locus_tag="KOU88_001696"
     CDS             complement(30957..31799)
                     /locus_tag="KOU88_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBK3211590.1"
                     /translation="MLVKNLIIYAVSDSVGETAQQVAKACMSQFYVNETYEIKRFPYM
                     INKGVLLETLENAKAENALIVYTLVDEELCSIVERYCEREGLSCIDLMTDILREISKR
                     TGRKPKREAGIIRKLDESYFKRVEAIEFAVKYDDGKDPRGVLQADIILVGISRTSKTP
                     LSMYLANKNIKVANVPLVPEIPIPKEVFEIDTKKIIGLTNSPEKLNEIRTQRLKALGL
                     SSKANYANLERILQELDYSEEIMKRIGCPVINVSNKAIEETAGIILDIMKENGLKIYK
                     EIEI"
     gene            complement(31806..32444)
                     /locus_tag="KOU88_001697"
     CDS             complement(31806..32444)
                     /locus_tag="KOU88_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211591.1"
                     /translation="MIIIQLNERQLKIIDIVKENEPITSESIASSLNVTRATLRSDLA
                     ILTMTGILDARPKVGYFYSGVSEINLIGKSVKEKTVEDIMSMPVLAKKDESIYDVIVT
                     MFLSDVGSIVIIDENEELCGVVSRKDLLKATIGGSDINKMPIGMIMTRTPNVVTLTKG
                     ASVLLASRKIIEHEVDSIPIVEYKGEDKNHMRVVGRISKTNITKLFLEIVDN"
     gene            complement(32880..34172)
                     /locus_tag="KOU88_001698"
     CDS             complement(32880..34172)
                     /locus_tag="KOU88_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBK3211592.1"
                     /translation="MLDLNRKLAKLEEEGKKIKVALIGAGHMGNGMVSQMANMKGIEA
                     SIVVDINLELAHKAFTDAGIDEEIIDNVTNEKDAEIKLQEGKVLTCNDFLVACKTKSI
                     DVVIDATGGIAIGAEIALNSILNKKHIVMLNAETDCVVGPILKKLADDAGVIFTGSAG
                     DEPGAVMELFDFADAMGFEVRVIGKGKNNKLDLDCNPDTVREEAERKGASPHMIASFK
                     EGTKTMVEMALMCNATGFVPDVRGGHGIEATVNEVPKKYALKSEGGVLDNYGVVDFVN
                     GIAPGVFVVVAHKLKAVNDELKYLSMGDGPNYILYRPYHLCSLETPLSAAMAVLDHKA
                     TIVPKAGLVAEVMTIAKKDLKKGEFMDGYGAYTCYGTIEKYDVAKAMNAVPIGLISKK
                     TKVVKDIKKGEVITYDMVEIEKDTTLYHLRQLQEKIFG"
     gene            complement(34209..34565)
                     /locus_tag="KOU88_001699"
     CDS             complement(34209..34565)
                     /locus_tag="KOU88_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBK3211593.1"
                     /translation="MKYEVKISGIGSLVKELMDESNCLIIYDETINDDDLKDISVIHS
                     IATLKSDVEIGDTLTIGNRDYCIVSVGDIAQKTLREIGHCTIKFDGKCEVNLPGEIHV
                     EIGNPDITIGDLITIS"
     gene            complement(34600..34959)
                     /locus_tag="KOU88_001700"
     CDS             complement(34600..34959)
                     /locus_tag="KOU88_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211594.1"
                     /translation="MKLLVILFVAYILNTIFIMKQNKLYFKTLNRAKKKGDIVSTGKK
                     KSYFSKGSIAIISSDSDGFIKFGEILKGRTVMAKFKEIEEIEGLDIYSAEQKFKDEES
                     IVQAIKFIKEKINVSFN"
     gene            complement(35028..37001)
                     /locus_tag="KOU88_001701"
     CDS             complement(35028..37001)
                     /locus_tag="KOU88_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK3211595.1"
                     /translation="MSVTEKIPSIDRKIFKILIMCSKKEFVSINSIANELNVTTRSVR
                     TYIKQLNKDLGNDIAVIKYIKGQGYKLEIKDEQILNKIIDMNRKNVFSLNSKEDRVEF
                     ILNYLIELDGFITLDSLADEMCVGRTTLVNDFQYVEKVLASYNLNLIKKQNTGMKLNG
                     NELDIRLFILNQLYKNSRKDFSNSKYFKGIKKEEIINLEEKLLTLFKKNNFYVTDEML
                     REVINYIVVLVYRVKEEKKVKDYDVKFDLLKSYDEYFIAREIKHIISGMFECTLNDEE
                     IIYLTIPLVSGNAPASECALNSSRISKNIDELMENIFNQIYVDMGIFINEDELRVGLG
                     YHLSFTLNRLLFNIKLKNVLLEEIKQNYILPFKLAQIAGKVIEKKYNLEVSEDEIGYI
                     AIHFSGYLERNSSRFYSIKKIAIICSTGLGTAKLLKIRVEKLIGNNPKIDTLSSFNLR
                     NINLDEYDIVFTTIDLDTSNINTIVLKINTIFDENKLREQLKTVLCLREGNIDTTNST
                     NLLINNLLDEDKFMILNEKTILASLEKMMDHLMDLGCIDDKFRKNIVNREEKSPTVFD
                     KGLLFPHSVNEKSDKFLMAVGILEEPIEYANRSIKIILMTMFPCENKIDSDLLVKIYE
                     EVLKIGQDVKLTNKISKCRTFLEFKKVLLKNLI"
     gene            complement(37223..38236)
                     /locus_tag="KOU88_001702"
     CDS             complement(37223..38236)
                     /locus_tag="KOU88_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBK3211596.1"
                     /translation="MEENKILKIEKGTSGWGGPLYIKKEGNRNKILSMTAGGIHEVTL
                     KIKELLGCEIVDGFKTGVSDEEVAVVIIDCGGTARCGVYPKKKIPTINVNPVGKTGPL
                     AKFITEEYYVSDVNPNCISVVDGEDMPQKSQENKSENKSSIRKPDNYDEVKSKAQGEY
                     AKKNIILSIGQGAGQVVSKFYDAGRDTIQMVMNNVIPFMAFVSMLMGIILASGLGDWI
                     ARVISPLAGNIGGLLIISVICTLPFLSPILGPGAVIAQVVGTLVGTQIGLGAIPAYLA
                     LPALFAINGQAGCDFVPVGLSLGEAEPETVEYGVPALFYSRLITGPIAVIIAYGVAVF
                     ALR"
     gene            complement(38249..38794)
                     /locus_tag="KOU88_001703"
     CDS             complement(38249..38794)
                     /locus_tag="KOU88_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBK3211597.1"
                     /translation="MENVITGLSKGAEWFIGLFQKGGEQFIGLVSGTLPTLIVLMVAI
                     NSLIKIIGEERVNNWASKLGKNSFTRYILLPLVSVFFLGNPMCYTFGRFLKEEHKAGF
                     YDAAVSFVHPITGLFPHANAGELFVWLGISAGLTTLGKETTTLALWYFIVGLIVIFIR
                     GIVTEKMYAFLTRKNRATNKA"
     gene            complement(39170..40039)
                     /locus_tag="KOU88_001704"
                     /pseudo
     CDS             complement(39170..40039)
                     /locus_tag="KOU88_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861549.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            complement(40191..41306)
                     /locus_tag="KOU88_001705"
     CDS             complement(40191..41306)
                     /locus_tag="KOU88_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HBK3211598.1"
                     /translation="METLEVRNIELSGTNYEIGYRLGELVANMPEILEGQINKSNVVS
                     KKEEKEMIELFDKYCPGLNEELQGFADAIQVNCNQILYYTMTYLKPGCSQVALAPELT
                     ENGHVLFARNFDFSHNMEDFVLCKTKVNGKYAHIGTTVMQFGRGEGMNECGLGVSQSS
                     CGIPVGNSDGLRKPAIVGLQFWAIIRYLLENCKDVDEALEYLKDMPIAYNINLLLADK
                     SGNIALVETLDGKKEVNIINSLESKREYFLHSTNHTHIDKLHKLEPQSMKNSIHRYKL
                     IKEYINKSKKIGEKELMNLLSSKYPNGLSCNYYNDFFGTLKSIVMDLNIGKFNILWGG
                     LENKWESYYLKNDIKSITQRININIEKAPSDFFDFIE"
     gene            complement(41542..42678)
                     /locus_tag="KOU88_001706"
     CDS             complement(41542..42678)
                     /locus_tag="KOU88_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK3211599.1"
                     /translation="MKERIIQVADSKKEKILGLCQSLYDEPEIALQEYKSAKKISEFL
                     REEGFDVEENLAGMATAFKATKKNGDGPKIAFIAEYDALPGNGHACGHHLIASMGVGA
                     GIALSSILDTYKGEVSIIGTPAEETGDGKPYLIEHGVFDGYDAAMMIHPNSKTCVTPE
                     IIAIGGLDFIFTGKASHAGAKPYNGINALDAVVLLYNNINALRQQLVDGTRIHGIILE
                     AGTAANVIPDMGKVRLEIRAKEQNYFDEVVEKVKNCARGAAIATGCELEFYHFEPTCQ
                     GLNENKVLVDIFTKIMEEFGIYEDEQVMLGSTDMGNLSQIMPCIHPLMKFSENGEELH
                     TKEFLEASINSYAKDRVIDGIKILALTGFNLFENPELLKKMKEE"
     gene            complement(42734..44197)
                     /locus_tag="KOU88_001707"
     CDS             complement(42734..44197)
                     /locus_tag="KOU88_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HBK3211600.1"
                     /translation="MTDLVNTINGIVWSPVLVAMCLCIGLYFSLKLKFFQIRDVKEMF
                     TLLLEGDSSHVGISSFQGFATSMAGRIGTGNIAGVAVAIAMGGPGALVWMCIMATLGS
                     ATAFVESTLAQIYKDEHEGQYRGGPPYYFEKGLGWKKCSVLFSIVAIISYTFFMPGTQ
                     SNTLYLAMNQAFGFSKMTIAVASSIALAIIIFGGIKRIGLFAEKVVPIMGGAYLIMTL
                     VIIITNISLVPEAIVTMFKSAFGFGSVFGGMLGSAISWGVKRGIYSNEAGEGSGTYGA
                     AAAEVSHPAKQGLVQAFSVYVDTLLICMATGIMIVITGMYNVTGVCTALPGVEPGPQY
                     VQSAINTLHPQLGDIFIAIVLLLFTFTTLLAFSYMMETNVSYLVTRIKAEKHEKYIIN
                     VCRFMLIACAAMCCFIEPLTSWALGDICIGVLTYINLIAIFTLKKPAIKAYYDYIRQK
                     KMGIKRSDRTFNPIELDIRNAEFWENRYLKEDKHELN"
     gene            complement(44842..46101)
                     /locus_tag="KOU88_001708"
     CDS             complement(44842..46101)
                     /locus_tag="KOU88_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3211601.1"
                     /translation="MGEKENGIKFGKLMFQLVIIAISWELVYIIPFIQYTLYDPILKA
                     LECTNTQLGFLLTIYGLGNIFGAPIGGWLADRFDYRKIILGSVFLNGVVSFLFAFNMN
                     YPFAVATWVGCAITSLVMNYPSMVKILRVIGKDNQGKVYGFNEAMVGVSGVVMGAIFL
                     YIYTCFATPTLGMRWVMISLGILSIAMCPVLWFVIKDVDIKEEREEAGEKMSAGDFIT
                     VLKSPNTWLVGISIFCVYSFTVTMSYFTPYITSVLGGSVALSGALAIIRQHGLKLFGA
                     PFGGYCADKLKSPTKVLLPIYVFGIAVIVLFLVLPASTPMTIFIALTFVVGILGYMGK
                     GIYYAVQDEVKVPVKYSATTIGIAAALGFSPDVFQFALIGHWIDTYGNKGYTYTFIFQ
                     IAILVIGILSCLYILKVKKRRASKLEA"
     gene            complement(46125..47333)
                     /locus_tag="KOU88_001709"
     CDS             complement(46125..47333)
                     /locus_tag="KOU88_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK3211602.1"
                     /translation="MKYAKRMDMVKASAIRDSQKKIAQKVASGGTVISFAAGLPDPNL
                     FPIEEISEITQKVLNERGKFALAYGPTKGEDELLDLLVKRMKEEENIDTKAENIIITT
                     GSQQGIALSAMILLEKGDVVVTENPSYLGAINAFRPYECDFLGVDTDEEGMVTDDLDK
                     LLSENSNIKVIYVIPTFQNPTGKTWSLQRRKDFMEVVNKYDVIVIEDNPYGEIRFTPE
                     PLPTLKSLDTKDKVLYLGSFSKVLCPGFRVAWMCGNVDIIDKAELLKQGIDLQSNQFS
                     QVQVIEFLKKYNLNEHIEKIRAEYKKRCLLMLDAMKKHFPEEAKYTEPDGGMFIWVEL
                     PESINVDDLLDKAIDAGVAYVSGESFFANNGPKNTMRLNYTTMSEEQIVKGVEILAEV
                     IKKELNYACE"
     gene            complement(47363..48256)
                     /locus_tag="KOU88_001710"
     CDS             complement(47363..48256)
                     /locus_tag="KOU88_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional enoyl-CoA hydratase/phosphate
                     acetyltransferase"
                     /protein_id="HBK3211603.1"
                     /translation="MLKDFNNLLEEAKKLEPVIVSVAVAEDKEVLKAVKSATDLNIIK
                     PILVGDKDKIESISREIGLKGHEIIGCQNPDESVKKAVEIVKNKEAKVLMKGLVNTSV
                     YMRAILNKETGLRTGRLLSLLAVYELPQYHKLLYCTDSGINVSPNLNQKKDIMTNALL
                     TMKSIGMENPKTAILTANEMVDPKIQSTVDANLLVEMEKSGEIPKCIVEGPIAFDVAF
                     DAHAAEHKGIKSNIAGDVDLLVFPNIEAGNILGKSWLRFNKAKWAGIVLGATNPIILG
                     SRSDTAEIKINSIALACLASQ"
     gene            complement(48274..49332)
                     /gene="buk"
                     /locus_tag="KOU88_001711"
     CDS             complement(48274..49332)
                     /gene="buk"
                     /locus_tag="KOU88_001711"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBK3211604.1"
                     /translation="MKVLVINPGGTSTKISVFQDENEILKKNITHTREDLKNFSKVFD
                     EYDYRKQLIVDILSSENHSINSFDAVVGRGGLMKAIKGGTYTVSEEMIEDMRNEINGE
                     HASNLGALLAKTIADEIGVQSFVVDPVSVDEFDDVSRITGISDIEKASWLHALNHKAV
                     SRKIAQKLGGKYEDYNFIVAHLGSGISIVAHKQGKMIDGSGGRSDGPFSPERSGGLLA
                     YPLIELCYSGKYTHDEMVAKVSSIGGMYDYLGTKDMIEIENRIKEGDEKAKLIMDAFI
                     YQVAKEISMYGASLSGNVDRVILTGGISHSEMVVKGVAEKVSYLAPIEIVPGEMEMEA
                     LALGALRVLNGEEIAKTY"
     gene            complement(49489..50028)
                     /locus_tag="KOU88_001712"
     CDS             complement(49489..50028)
                     /locus_tag="KOU88_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBK3211605.1"
                     /translation="MLNEIICAGFGGQGVLTAGKIIMYVAYKAEKKITWFPSYGNEMR
                     GGSANCNVVVSDEKIANPCVKNPDILLGMNSVSVDKYESLMKKNGYMFVNESLVSKDR
                     KYREDINVIKVPVTEIAQNLGNEKAANICMLGAMVKSLDLFTKEEFESGMCEYFENQG
                     KGKFNSKNVEAFEAGYDYE"
     gene            complement(50041..50760)
                     /locus_tag="KOU88_001713"
     CDS             complement(50041..50760)
                     /locus_tag="KOU88_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBK3211606.1"
                     /translation="MAKKAPAIMMCENMFCGGCGHSIVDRIIGEVLTEMDICQDTIIC
                     SDIGCNHMFQFSMNVDVVVPPHGKMGAAMAAMKRVRPDKYIFTIAGDGGAYAIGLGET
                     MSAATRNDNVIFLVMNNNMFAMTGGQMAPTTIEGQYTASTPAGRNYADHGSTFDVVKV
                     MGNLDIAYLARGTITNPKEINTTKRYIKKALEKQKEKKGFCLIEVLVPCPTNWGLKPV
                     DAMKRIENELVPKYPLGEFID"
     gene            complement(50763..51839)
                     /gene="vorB"
                     /locus_tag="KOU88_001714"
     CDS             complement(50763..51839)
                     /gene="vorB"
                     /locus_tag="KOU88_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBK3211607.1"
                     /translation="MQSLLIKGNEALAEGAIRGGCRFYAGYPITPQSEILEMMAWRQK
                     EVGGVFIQGESEIASVNMVMGASALGARAMTSSSGPGFSLKQEGIAYWVSAGLPAVVA
                     CVQRYGIGDGFIGAGQDNYWQAVKGGGNGDYHLIVLAPNSVQENMDMAYESFELAEKY
                     MHPVLILSDATIGQMVEPCIAPPMKEYDMDKAPWAAKGTPVGEKNKVITDITYFEDQD
                     TWQKGYIEKMRKVQEDEQRWEEIEIEDAEVVFVAYGISSRIAEGAVRDARAKGMKLGL
                     IRPKTLWPYPRKAFKKLSDSLKGLVTVEMNMMAQMKEDVIIACDNRFPVYSVATAQYM
                     AEVNQLIDFAQQIIDGKAKQEEVF"
     gene            complement(51868..52065)
                     /locus_tag="KOU88_001715"
     CDS             complement(51868..52065)
                     /locus_tag="KOU88_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3211608.1"
                     /translation="MEKVKLSVERCKGCYLCIEACKKDAISLSDYTNKKGFVTIKVDE
                     EKCIQCGACYTMCPDLVFEIL"
     gene            complement(52348..53115)
                     /locus_tag="KOU88_001716"
     CDS             complement(52348..53115)
                     /locus_tag="KOU88_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBK3211609.1"
                     /translation="MGEIINALDRALDIILLLYHEKREMGITEISKAMGVYKSTVHRT
                     LVTLENKGFVIQNAENGKYWLGINLYAIGMVVGEKMSLTEIVKPYTKKLNQEFNEVVN
                     VSILEERAQDSPRSIIIHKEYGSNQLLSVNPSVGSSSECYCSAVGKCLMAFNDSIDFE
                     KYRKTPIHKYTEHTIDNWDDMMLFLAKIKEQGYAIDDEELEHGLTCIGAPILDKNNKA
                     IAAISLSGPTIRMREGDFEYKIKRVIETAKSISELFR"
     gene            53395..54942
                     /locus_tag="KOU88_001717"
     CDS             53395..54942
                     /locus_tag="KOU88_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite/sulfite reductase"
                     /protein_id="HBK3211610.1"
                     /translation="MDNFKKILLNELPNFKEYSSKFLNGEINKMQYKGFSGGYGVYAQ
                     RDKKSFMIRLRVSAGVLSQYQLNKIYEIAIKHNLDKIHLTTRQAIQLHDLSINSIVDI
                     MEEGIKNDIFTRGGGGNYPRNVGLSPLSGVDPSEVFDVTPYAVATDKYFIKNATTYHL
                     PRKLKVSYSNCYTDTAHCSIQDLGFVATLKNDEPYFRVFLGGGLGKQPKVALELDELI
                     KPKDALYCVEGMIKFFMDYGNYENKNRARVRYMVESLGEELFLEKFKEYYKLEKENGS
                     LELNIEEIDYSKPGVKIDIQDSRLIPQKQDGLYTVYIHPVGGILLTKDLSTLLKELDN
                     VENPMIRLGMTEGLYILNLNGNEAKRILEISKTISCNSQLEQSISCIGVPICQMGIQN
                     SQKMLHEIIDYFRLQNNEEILNKAPKLYISGCLNSCGVHQVGSIGLCGKKKNVDGIST
                     DAFELFVGGSFEIGKTRLGKSLGDFKASDIPEMLYKISDASSGNFYEWVNSNDNILNK
                     ITDKYKI"
     gene            complement(55108..57174)
                     /locus_tag="KOU88_001718"
     CDS             complement(55108..57174)
                     /locus_tag="KOU88_001718"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBK3211611.1"
                     /translation="MKNYLLFEIGVEEMPSRFVGSTLEQLKNNLSKLFDENRIAFDKI
                     NAYGTPRRLTLVVEGLSDRQSDLEEEIKGPAKKIAVDAENNLTKPALGFIKSKGLSES
                     DIYFKQVGKEEYIFATIKQDGKETSEVLKDILPETIKSVVFPKAMRWGGKNLKFARPI
                     RWIVALLNDKVLEFDLEGIISSNVTKGHRFLGESTIEVDSIEDYFEKLEKNYIVLDQN
                     KRKEMIRKQCIEVANSLGGEVEFDEDLLEEVTYLVEYPTAFYGEFDVDYIKLPKEVVI
                     TPMKQHQRYFPVLKEGKLLPNFIAVRNGDSYRIDNVKAGNEKVLEARLADALFFYRED
                     TKRNLESYIEKLKTVVFQVKLGTIYDKTLRLEKLSADILDSLGLVDEKADTIRAAKLS
                     KADLVTGMVGEFDELQGFMGKEYAKVGGENDVVSEAIFEHYLPRFAGDILPKTNAGVA
                     LSIADKLDSIAGFFAIGIQPTGSQDPYALRRQALGILSILMDRKVAVDIKILIEHALD
                     NYSELDFNKEEVVEQIMNFFNERVKNLFKDLGIRYDVVDAVLSSDINDVSDMHMRALE
                     LNNWLEKDELVEMLTAFNRVSTLAQKAESDKIDESLLKEDAEIKLYNEFKQVKVKVNE
                     LLKDKKYGIALDEFASLRPVVDNLFDTVMVMDNDEAIKNNRLALLKQVYDTMLGICDL
                     SKIVYK"
     gene            complement(57174..58052)
                     /gene="glyQ"
                     /locus_tag="KOU88_001719"
     CDS             complement(57174..58052)
                     /gene="glyQ"
                     /locus_tag="KOU88_001719"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBK3211612.1"
                     /translation="MNFQEMILALQKYWSKQGCIMMQPYDIEKGAGTMNPNTFLRSLG
                     PEPWQVCYVEPSRRPADGRYGENPNRLYQHHQFQVILKPSPDNIQELYLESLKEIGID
                     PSEHDIRFVEDNWEAATVGAWGLGWEVWLDGMEITQFTYFQQVGNIECELETGEITYG
                     LERLAMYIQEVDSVYDLKWNDKITYGEVFNKAEYENSMYAFELCDADMLFNLFDIYEK
                     EALRLMENGLVIPSYDYVLKCSHAFNTLDARGAIGVSQRASFIGRVRNMAKTVAETFV
                     KQREEMGFPLLKDGDK"
     gene            complement(58212..58811)
                     /locus_tag="KOU88_001720"
     CDS             complement(58212..58811)
                     /locus_tag="KOU88_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4342 domain-containing protein"
                     /protein_id="HBK3211613.1"
                     /translation="MSSNITIEMVDSVFERVPGATYAEAKEALVMCNGDVIEAVIYLE
                     NKKNTCNCKAKSAKETMEEVFGKDGENIKFQLKELLRKSSVVRIIVEKDGKTMMNIPL
                     TVGVVGLAFVPLATLVGLSAAVISKYRIKVQNEEDGEIVDLGELNEEKLHVLKNMITN
                     AAKDVKDVVVDKKEDDKDVTADLMKEESEKNKEDEDENK"
     gene            complement(58804..59577)
                     /gene="recO"
                     /locus_tag="KOU88_001721"
     CDS             complement(58804..59577)
                     /gene="recO"
                     /locus_tag="KOU88_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBK3211614.1"
                     /translation="MIILNTQGIVLKAIRYKESDIILTLFTRKLGKVSAIAKGAKKNK
                     SSLLSSSQLFSYSNFTLKKQGNMYKVTQSEIIKSFYNISYDIEAFSYATYITKLVENS
                     ILENQTNNRLFILLAQTLYLYTQDNTDNRFITAAFELKFLDYIGFKPIVNKCINCECK
                     ILQNSVFNIYEGGILCSKCSKLFDNNIKLDLTTISLMEYVLRNDILTCSKAKVSKYIT
                     HELENILDKYLKVYVDNINFKSLHVLQSVKNNKGVDNDE"
     gene            complement(59543..59698)
                     /locus_tag="KOU88_001722"
     CDS             complement(59543..59698)
                     /locus_tag="KOU88_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqzL family protein"
                     /protein_id="HBK3211615.1"
                     /translation="MNNISWEVFKKTGSIDAYLYFCDCKNIHEEIEEVREKKEDDDNP
                     EHPGDST"
     gene            complement(59771..61150)
                     /gene="mgtE"
                     /locus_tag="KOU88_001723"
     CDS             complement(59771..61150)
                     /gene="mgtE"
                     /locus_tag="KOU88_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBK3211616.1"
                     /translation="MDRKLDASQDLLYEVKSLIDNNKVLELRELIEEYHIIDIFDIME
                     NLEEDMKIQLFEVLPLDMASSILEEGSVEFFISILSKLDVEHSKNILELMSLGDMADK
                     LSELEEEEREHIINLLNQENADYVKELLFYDEDSAGGTMTTGYISINKDMTALEAIDH
                     MREEAEEAETIYYIYVVDDEEKLVGVLSLRELIIARDANIVEDLMSENIISVYVDEDR
                     EEAVRLVSKYNLIAIPVVDRQEKLKGIITVDDIIDVMEEEATEDMYKFAGSSEHEREV
                     AEKENPTLREQIISALRGRLPWLIITLVGGLLASLILSNLDYIMNPVYAPLVFFIPVV
                     IGMGGNIGTQSSSVTVITLSNKDLNFSNVVREGIVGIITGLLCSIITGIVIYFVMRKL
                     DIVLIVSISLFINMVLGATIGAFMPVLLKKMDADPSTVSSPIISTALDITGIAVYFII
                     TTALLSKIV"
     gene            complement(61162..62055)
                     /gene="era"
                     /locus_tag="KOU88_001724"
     CDS             complement(61162..62055)
                     /gene="era"
                     /locus_tag="KOU88_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBK3211617.1"
                     /translation="MFKSGFVSIVGRPNVGKSTLMNNVVGEKIAIMSDKPQTTRNTIQ
                     AVYTDEEMQIVFLDTPGIHKPKNKLGEFMVKAATEAFKNVDLILFVVDDSKKIGPGDR
                     KIIEDLRSVKTPIILVVNKIDQLDQKDELFDIIKMYDREGIFKEIVPISALKGKNTDT
                     LIKVIQNYLEEGPKYFPDYMITDQPERVLIAELIREKVLHYLNDEIPHGVAVEIEKMK
                     ARNDKEIVDVSAVIYCERDSHKGIIIGKNGRKLKGIGKSARQDIELLLGSQINLQLWV
                     KVKENWRNLQNYINNFGYNDK"
     gene            complement(62119..62520)
                     /locus_tag="KOU88_001725"
     CDS             complement(62119..62520)
                     /locus_tag="KOU88_001725"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBK3211618.1"
                     /translation="MDNIELLRLAEDARQHSYAPYSGFRVGAALLTKSGKVYTGCNIE
                     CASLGGTNCAERTAIFKAISEGDKDIYKIAIASDNSENNEQTYPCGICRQVIIEFGSD
                     IKIITGYTKGEVFEHSIKDLLPNYFSGNDLK"
     gene            complement(62639..63358)
                     /locus_tag="KOU88_001726"
     CDS             complement(62639..63358)
                     /locus_tag="KOU88_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBK3211619.1"
                     /translation="MKPEKTRQGIIKAFNAAIEGILYTFKFERNMKIHYLGSVAVLII
                     SLFFNFSKLEMIMLLMSICLVVVAEMFNTAIEKAVDLVTDEYHVLAKIAKDVAAGGVL
                     VAALNSVVVGYILFYDKLTDISGILIYKIRESELHITLICILLVLIAVVVVKALTSTG
                     TPLKGGMPSGHAALAFAIATAITLMTERVVASTLAYIMAVLVAQSRIEGKIHTFWETI
                     AGALLGVLIAILVFQLGMFYN"
     gene            complement(63364..63825)
                     /gene="ybeY"
                     /locus_tag="KOU88_001727"
     CDS             complement(63364..63825)
                     /gene="ybeY"
                     /locus_tag="KOU88_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBK3211620.1"
                     /translation="MDLILDDRQDKLEVSEELIEKIKDIIIECLDYEGYDDNYEVSLS
                     FVDNKEIHELNREYRGVDRVTDVLSFPLLSDDFEDVELEEESLGDIVVSLERALEQSI
                     EYNHSFEREVCFLICHSMFHLLGYDHDTDENTKEMREKEEHILNKLNITRE"
     gene            complement(63882..64997)
                     /locus_tag="KOU88_001728"
     CDS             complement(63882..64997)
                     /locus_tag="KOU88_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBK3211621.1"
                     /translation="MKIIVIKIVIIVKIIIAITTNKIKLKILGGLIQLIIQKKFTIAD
                     GNFERELFGNFDENVKLIEKTLNIDVILREGNIILIGEEKNVDSALKLMNELHQTVSN
                     GKHLDKQSISYSLSLLLEGSEQKIKELEGTIVITQRGKAVQPKTLGQKEYIKLIENND
                     ITFGVGPAGTGKTYLAVAMAVKAFKRDEVSRIILTRPAVEAGESLGFLPGDLKDKVDP
                     YLRPLYDALFEMLGADKFNKYLERGTIEVAPLAFMRGRTLDNSFIILDEAQNTTSEQM
                     KMFLTRLGFGSKAVVTGDVTQTDLPQNKKSGLIQATEILKGVPGIGSIMLTDRDVVRH
                     ELVQRIIRAYEKHDKREEFKKEERKKAKMQEKTFKRK"
     gene            complement(64936..66279)
                     /gene="yqfD"
                     /locus_tag="KOU88_001729"
     CDS             complement(64936..66279)
                     /gene="yqfD"
                     /locus_tag="KOU88_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YqfD"
                     /protein_id="HBK3211622.1"
                     /translation="MISFIRGYYVIVVEGVGLEQFLNHLIRNGISVYNVTRIKNTKME
                     FHIDRQDIKDFKNVYRGSKFDIKVKQKTGVPFIIKRVYKHKGMWICALVSLFLLMSTS
                     QFVTDVYIQSPEGIKKEALRNEIYKVGVRPGVYKKSIDRKEVRDHMMSKFNDVAYLSI
                     NVKGTNIFVTVTKKAESLKSTDQSNYCNVIALKNGIIEKVIPRSGKSVIKSGDIVQKG
                     DVLLNGANTKSIPEVWASTFYESTKKASYVDTVNKKTGEKKNIYTLSFYDKEFTMRKN
                     IKYKDYVVENKEKKLSIGNYTFPIKIKTSTFYETKKVEVKRNKEELKKELSEKALKEL
                     EYIIPASARIIDVKHNFKVNKNMLEYLITVQTSENIAKIYPLSKSEAERFIKEESKPD
                     EGEEEVPSNPEKRPLNDIRNEFDEDNKDNKDQNNSDENNSNQNSNNSQNNNSNNN"
     gene            complement(66292..66528)
                     /locus_tag="KOU88_001730"
     CDS             complement(66292..66528)
                     /locus_tag="KOU88_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YabP/YqfC family sporulation protein"
                     /protein_id="HBK3211623.1"
                     /translation="MLEISTDLQVNQPVITVTSNTFISIENYLSILEYEVDLIRIKTK
                     VKTIKISGDKLSLKYITDSEIGIKGIIYNVEYVD"
     gene            complement(66741..67304)
                     /gene="raiA"
                     /locus_tag="KOU88_001731"
     CDS             complement(66741..67304)
                     /gene="raiA"
                     /locus_tag="KOU88_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBK3211624.1"
                     /translation="MQIIVSGRQMKLTDGIKGYVDGKLSRLEKYLDPESEVKVTVSAK
                     KDRQKVEVTIIPINGQIIRAEDVEDDLYAAIDIVCDKLSRQVVKYKTKVKDKVQNNKS
                     IRFENLDFIDNSSEFDDYDYDDEEDENIVIERRKKFNVKPMSSEEAILQMELVGHNFY
                     MFRNQDNFEINIVYKRKAGGYGLIEQD"
     gene            complement(67497..67994)
                     /locus_tag="KOU88_001732"
     CDS             complement(67497..67994)
                     /locus_tag="KOU88_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBK3211625.1"
                     /translation="MIISVKEIRNFLINIFIPLIIGYLSSILTMIISGTDISTYYLQL
                     TKPSFAPPAFIFPIVWTILYILMGISSYLILRKGYNLPKVRDAIFYYGLQLVLNFIWS
                     ILFFGFGLRFTALIDIIIMILVSIIMISKFSKIDKRSGYINLIYLMWLVYAGFLNYFI
                     WFINK"
     gene            complement(68105..68548)
                     /locus_tag="KOU88_001733"
     CDS             complement(68105..68548)
                     /locus_tag="KOU88_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBK3211626.1"
                     /translation="MSLKQKLQEDLKSSMKNKDTVRKSVVTLIRASIKQYEVDNRVEL
                     DEDGIIDVIAKQLKQRRDALVEFEKAGREDLIKETEGEIEVLKEYLPQQLSEEELEEI
                     VKSTISEVGATSMKDMGKIMSVIQPKVKGRADGKLINKLVKQNLQ"
     gene            complement(68578..68757)
                     /locus_tag="KOU88_001734"
     CDS             complement(68578..68757)
                     /locus_tag="KOU88_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBK3211627.1"
                     /translation="MSEVRVRENETLDSALRRFKRQCAMSGIMSEVRKREHYDKPSVK
                     RKKKAEAARRKNAKK"
     gene            complement(68920..69270)
                     /locus_tag="KOU88_001735"
     CDS             complement(68920..69270)
                     /locus_tag="KOU88_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine triad nucleotide-binding protein"
                     /protein_id="HBK3211628.1"
                     /translation="MDCIFCKIANGEIPSTKVYEDDRVLAFNDLNPVAPYHILVVPKK
                     HYDSLIDIPDKEMDIVSHIHVVINKIAKEKGFDQTGFRVINNCGSDGGQEVKHLHYHI
                     LAGKKLPNYEAGQN"
     gene            complement(69313..70611)
                     /gene="mtaB"
                     /locus_tag="KOU88_001736"
     CDS             complement(69313..70611)
                     /gene="mtaB"
                     /locus_tag="KOU88_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HBK3211629.1"
                     /translation="MKKVAFYTLGCKVNQYETEAMLELFEKDGYEQVNSEEYADVYVI
                     NTCTVTHMSDRKSRQYIRRVKKKNPDAIIAVVGCYSQVSPEEILDIEEVNLVMGTNDR
                     RKIVEEIKKINSSKKVSTVDDIMKVKAFEEIEISQTNGKTRAFMKIQDGCDRFCTYCI
                     IPYARGRVRSRDIDSIVDEVKKLANNGYKEVVLTGIHVASYGKDLKDRDIKLLDVIKQ
                     INQIEKIERIRLSSVEPILFTDEFVNEVLKMDKVCPHYHLSLQSGCDETLKRMNRRYT
                     TLEYKTIVDRLRSKMPDVAITTDVIVGFPGETNEEFKKTYEFLKEIELSQMHIFKYSP
                     RKGTPAATMENQVDPQMKHFRSEQLLNLSKVNFNKFATKFIGRELDVLFEQNIEGNKY
                     EGLTSNYIRVVVESDKNIQGQILKVKINDVKDEYVEGILL"
     gene            complement(70613..71371)
                     /locus_tag="KOU88_001737"
     CDS             complement(70613..71371)
                     /locus_tag="KOU88_001737"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBK3211630.1"
                     /translation="MDRFFVEKNNINLQDKTCTIEGEDVKHISKVLRCKLGEKLEICD
                     KNNNEYICEIMNIDKSIVNLEILEKVDINRESELKVRLYQGLPKAPKMEMILQKLTEV
                     GVEEIILVQTKRSVVKVDDKKEDKKFERWERIIYEAAKQSKRGKIPKLRGVLSFKEAL
                     EDMKKNNVNICPYENERTVSIKHALKKCDSNIDSVGIFIGPEGGFSEEEIEQIQKNNC
                     NVVSLGPRILRTETASVVASTIALYELSDLGGEK"
     gene            complement(71390..72337)
                     /gene="prmA"
                     /locus_tag="KOU88_001738"
     CDS             complement(71390..72337)
                     /gene="prmA"
                     /locus_tag="KOU88_001738"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBK3211631.1"
                     /translation="MNNWIEVTIKTTTESVEPITNILYEQGAGGAVIEDPKDFLFQKK
                     NELDWDYVEEEVFKKNEEDDVLIKTYVSEEKNVMEFVEIIKQKVLGLKGFGIDIGEGS
                     VSLDQVNEADWANAWKAYYKPTKVGQRVVVKPTWEDYAMQEGDLIIELDPGMAFGTGT
                     HETTSMCIRELEKYVNKDSKVFDIGCGSGILAIAAAKLGAKEVVAVDLDEVAVKVAKE
                     NVLENKVEKSVSVMHGNLTDVIKDKADVIVANIIADIIKILAKDVQNFMKEDAIFISS
                     GIILDKVEEVKESLIENGFEIVEVQKLGEWSAIVSKLKK"
     gene            complement(72778..75186)
                     /locus_tag="KOU88_001739"
     CDS             complement(72778..75186)
                     /locus_tag="KOU88_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBK3211632.1"
                     /translation="MKNIMQKEILAKSYNLRTNQQEQTLVEHIKDLFEVLESILELNL
                     YSDKDVEILKICCALHDLGKINSIMQQKMEINNKISYSCSEEERKKLESDKKSLKKIA
                     RHNIFSGAFLKDILEKMNLSEEDKLYIYKSIMLHHGNYEDYMRLSISKVQEEIYEYIE
                     KGILEKEEFNLKDIESYINSILNVDFKFGEDVLDYDYIDKLSESMFIDSDYNNGQIDD
                     SVLNYRKFKYILYKGMLNLIDHSASSRQKGIKFYNDFTDEEIDNMILNEIYKSQGNLE
                     KNNIEFNTIQKRLRELSGRNVLTVAFTGSGKTAADYRKTFKRKFFLVPNKISAESFYR
                     KNIFQNKNDLDTRSSNDYIGLLHGDINLYSENEDNGEHDFVLTLRDIDLSINFCKPCV
                     IATVDQLLLSMFKFPGYEKIFAAVKNASITVDEVHLLEPKMFLILIYFMQFACKYLDV
                     DFHLMTATLPKSYKEQMINKGIIFQEESNENVTDKGEIVFIESNKEEEICEGKDVKVS
                     FIKEKEIKSIVEDALENKQKILIIKNTIDSVNRTYEFLKENLSDKYGGVDIDVLHSRF
                     KFKDKKEKYSKILNGEGDIWISTQSVEISLDLDFNIIISDLATMDSLIQRMGRCNRNN
                     KYEYGNFYILPSEDKIYDNKLKNTTKNILKDILKTNSIFTMGIRKTILDDYYDNSVVK
                     KYFEENFISCDKEIKNIYGINKEIFDGLDLIFNFEPYKNIVDSKKEAAKIFRDVDVSY
                     KIILEEDFYKEDRELQQDSIQVSGFIFNRLYYYGLISKVEGYMVLKSSSKFEYNSTVG
                     LILK"
     gene            complement(75213..76010)
                     /gene="cas5"
                     /locus_tag="KOU88_001740"
     CDS             complement(75213..76010)
                     /gene="cas5"
                     /locus_tag="KOU88_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated protein Cas5"
                     /protein_id="HBK3211633.1"
                     /translation="MKVLQCKLKQPTAHYRDPKVFQNEYISTLNLPSKTTIMGMITYL
                     CDRRLNSDIDIGIIGTHHHRELEFSRGENIDFWNEYTNMRKGKDKEKFLLQGNYYDYY
                     KEHKAQNSILNYEVLKEVELTIFISCKDDEELEFIRKKLESPCKYANLGRKEDFVIPS
                     EKGCFVKEVELKEVIPMNTRDAIKENIKLKNTYVRVDLRDKENVETIINQGVLIALPY
                     KYKDLEANRDDRVYEFCHYIYVDNDGIYPKNIKVNVCIDTKEVFTWL"
     gene            complement(76026..>76159)
                     /locus_tag="KOU88_001741"
     CDS             complement(76026..>76159)
                     /locus_tag="KOU88_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBK3211634.1"
                     /translation="DRLKISNKKELNKFNLSKYPVKEIKNLADRLEIGEDNMWYLKE"
BASE COUNT        24935 a        13154 c         8400 g        29670 t
ORIGIN      
        1 agatttttca ttactttttg cataatacat ggctaaactt ataaataaat caaacttctc
       61 tacttctttt aagctatgat ttttaatttt ttctagatat acttcagatt ttgctaaatt
      121 atttattgcg acaggataat ttctagtctt tattaatatt ttagttatgt tgtttgatgc
      181 tctatatttt tgaattatat ttacatttct atacttttta ttgcttatta cttcattgaa
      241 atattccatg gaacattcat aattttcaaa cgaacattca cactcaccta tctttatatt
      301 acatagtgaa gatacttgca tatcctttag taaatctgca tattttcttg cttttaaaaa
      361 atttacctta gcaattagag catcatccaa aaacaaaaaa tatattttac caataataaa
      421 aaaatatatt tttttacaat taaaatcgtt aatttctttt atctttatat acaacgtttc
      481 tatttcttta attattacag aagattctat acacttactt gccttaatgt aaataagttg
      541 tgatttaaaa ataatttctt caattagaaa attattttca tcacaaataa gattaaattt
      601 atccatatat aaatttgcct tatttacatc ttcatttttt aaacttaaaa tagctatttg
      661 tgaataaaat cgtgctaaaa atttataatc tttgggtaag catttatcaa tatatttaca
      721 ggaaatcaaa atatactctt tcattttttc actaaaccct tgaataccat ataataaagc
      781 tagcaaaaaa tttgatttta ataacattaa actattttgt tcagttttat agcaatcaat
      841 taaattcttt actacatcaa ttttattttc aataaaatcg ttattagtca ataatctttc
      901 attcaaggtt agtttaaaca ttgaatctaa aattgtatca tctatctctt ccaaatattt
      961 actatatatt gtaactcacc tccgacttac attatctcat aaatttagta attttccata
     1021 ctatttttga aaaaagttga tgtctcaatt tagaaatttc tcttaaatta agacatactt
     1081 tacactaaac tatacaattt tctatctgaa ctatataatc ctgacaattt tcgcaaatta
     1141 tcacacttac aatataacta ttatcaactt tatttgccct tgatagttta ttaaaagata
     1201 gtcctttata atcaacagat atattgctta ttacatattc tccatcttta ctgaaaatat
     1261 aaaagtgata ttctaaaaaa ggaaagaatt ttttcttttc ttttactcct tctaaacata
     1321 atggacatgc ttcttgataa tattctacat caaaatcaac ttcttctgct tcattaagta
     1381 tatcaattat ttttgaaata cttactcctt gaactggatt ttcttcatca tttattaaag
     1441 cactacagtt ctcctctttt aataaatatt ccttatcatc atatataaac ttatataaac
     1501 tcatattata tcctccttat aattattaat ctccaagtta ttctaccatt taaataaagt
     1561 taataaaagt aattgtttat aatctttata attaagttat gtatacatat attcctatgc
     1621 gctatcttaa ttaatgattt taaaatccaa gtttgcactt tgaacatcca gtttcccaaa
     1681 atctattgtc aaaactcact ttagttatta atataatgat ataaatatat aactgcatag
     1741 atgttacaca cttaactatt taatatgata cgatttggta tctaaattta tatattgtat
     1801 atagggggag atatatatgt ataaagataa aagtgatgaa tgtatacact taatgactgc
     1861 atacatcgat agtataagtg gatattattc atttattgac acacaattag aggattttat
     1921 gatgaaatat ggtgaaaaca ttgttgattc aaatttacac agtataatga tgctgctttg
     1981 taaatgggga ttatcttagc atttcaagaa acttttttgt atattgtatt ctatattatt
     2041 tattcattaa caaaaaagat tgacataaac ttaaaagcta tatatagatt tctttaaaaa
     2101 tctatatata gcttttttaa ttttttcaaa atgtatactt aaataagtta gtttttttca
     2161 aaatttgact atctaatatg atataattta actatctaca acaataaaaa atatctaata
     2221 tgtattatct agtttagctc atcataataa catccctata tttacaatta agatattttc
     2281 aatatagtaa tactcaattt taatattata aaaaggagag attttgtatg aattacaatg
     2341 acttactaaa atcagctaga gagaacttta atggaacatg taaagtatgt aaaatttgta
     2401 atggattagc ttgtgctgga gatgttcctg gtatgggtgg taaaggaagt ggttcgtctt
     2461 tcattgaaaa tagaaaaagt ctagaaaaaa taaagataaa tatgagagtc atacataatg
     2521 tttcaaagcc agatacatcc atagaattat ttggtagaaa aatgagttct cctatattcg
     2581 ctgcacctgt atcaggtact atattgaaca tgggtggtaa agtttccgaa aaagaataca
     2641 tagagcctgt tgttagaggt tgttctaatt ctggaattta tgctatggtt ggcgatacta
     2701 atgtagatac ttttttactg gataatttag atgtgttgaa ggataataga ggaaatggaa
     2761 ttgtatttat aaagccttgg aataattcaa agataataga aaaaattaga ttgtctgaag
     2821 aagcaggtgc ttttgcagtt ggtgtagacc ttgatgcttg tggacttatt aataatcaat
     2881 ttcaagaaaa tcctttttct cctaaaacaa ttgatgagat tagagaattg gttgaatcca
     2941 ctagattacc ttttattata aaaggaatta tgactgtaga tgatgctttg atggctgtag
     3001 agtctggtgc tagtgccatt attgtttcaa atcatggtgg aagagtactt gattatactc
     3061 ctggtacttg tgaggtactt ccagctatag ctaagtctgt aaagggaaag ataacaatac
     3121 ttgttgatgg tggcgttagg actggtgttg atgtagttaa gatgcttgga ttgggtgctg
     3181 atgctgtttt gatgggaaga ccttttgtta ctgcttcttt tggcggtggt cttgatggtg
     3241 tggagttttt tatagagaag gttaggaatg agttatgtga gactatgatt ttgactggtt
     3301 gccaaaatgt taaggatata gatggtagag ttatatggaa tttattgtaa aatagtttta
     3361 taacatttat atttaaataa tatatccttt aacgtataca aaatagtatc tcatttagtg
     3421 tttaataaat catattgaga gagtctggaa atatttatgt ctattcttta aataaaaatt
     3481 tattttttaa atgataatta aatttttact gataaggcta tagctttaaa aatcatagcc
     3541 ttattttgat attttttcca tttttgcaaa aattattatc actttaagaa aaattcttga
     3601 ttttttgaaa tatttcttat taatttagat ttaaatttct ttctttaaaa taaatactta
     3661 aataagataa aatttgagtc catttttcag aaatatatat agttgctaag tataatgatt
     3721 tgtgcaaaga atcatctgaa ggaaaaatag acttcgattt agtaactttt cttaataatc
     3781 tattgtaaat ttcaactgat tcaccaactt cttaatgcta tcgcatattg attgcccctt
     3841 ttttctttta agagcaatag cttacttaac gcttattctt ctataattga atcctatatt
     3901 ttctttaaat ttcttgcaaa tttttttcta tttttatatg atacataatt taaagtattt
     3961 ctgatttgat gcacaacaca tctttgtatt tcagtatcag gaaatactgc tttaattgca
     4021 tcagaaaatc taactaatcc atctacagaa gctattaata tatctttaac tcctctgttt
     4081 ctaatatctg taagtacctt taggcaacat tttaaacttt catttctcca acccatggtt
     4141 cataaaacct catttatccc ttttaagtta atacctgtag ctatagatgc tgctttttta
     4201 tttattctat tttaacttat aactttatac tatatagtat cataaataca attgaataaa
     4261 tcatatcagg aagtctactt tgctattcat gagctaaaga tataactata tcagtagctt
     4321 tagctattaa ttaattatat atgtccattc cataaatact tttaatgtgc cttgatatat
     4381 cttgagtaga catacctttt ttgagtatat tccaatcact tggttctcta tttcagatat
     4441 atcactttca tagtttctaa ttacatttgg ttcaaaatct caatttcagt ctcttggaat
     4501 atttaaagtt atttctccaa aatctaattc aacattttta tttctatatc tatttctaga
     4561 gtttttagca gttttattct tattatcata acctaaatag tcatcaaact ccgtttccaa
     4621 catttgacga attgtacttg caaataaaac ctttagtatg tcttgaatat ttgtagttgt
     4681 tttgacatca tattcttcaa taagtttttt aatatttcgt ttttgttaaa cataaaaagt
     4741 gtgtaccttc ctttgtatag tgatatttta tattttaatt atcatcactt tttagaagaa
     4801 tacacacttt attttaaaag ctcttaagaa atcacattgg aacactattt aatattagat
     4861 tttaatccta ttaaaaacta gaatcagtta atctacccaa tttatcccaa gtagctggac
     4921 caatcactcc atctgcagat aaaccatatt ttttttgtac acttacgacc gcattatatg
     4981 tcttacttcc aaaaatacca tctggacttg tattgtaacc tagtttagat agcataattt
     5041 gcgcaactgt aacttctttt ccagtatcac ccttacgtat aacttttgtt gtacttatag
     5101 ttataaattc accaccacct ataactgtta tggttttctc atcaggttta taagcaacag
     5161 cataatttgt ataaacagct ttatcatcat cattcattag attagctgat gttggaacaa
     5221 agattttatc atctggctta ggtgcgatat ttacatcttc acaattctgt ttatgttcat
     5281 ctcttatttt ttgtggagca ttttcatatg tatatacata cccagaaata ttaaaagaat
     5341 atgtgttttt ctctgaaaca gcttctttac tcactccttc tcctttactt gcgtcagcaa
     5401 atgctacact tgtaaaagta agcattaagc aacacataat agctaatgtc ttttttgatt
     5461 tttttaacat aaaatcctcc ttataattat ttcattaatt cattgaaatc tttagtatta
     5521 attattattg tatcataatc tttaggtgtt gtacctttca atttacagtt atcttcataa
     5581 aattttctaa ttttacttgg tgcatcttta taataaaaag tttgatgttt atcagttgac
     5641 ttattcagta taaagtcatt aatattgtta tttatttcat tgatactatt attaatttta
     5701 atctgagcat caacttcaat aaaagatgtt atagaagtca taattactaa tatagcaatt
     5761 aatattccac ttctaccttt cttcttaaca atactctcaa gtctcttttc taaatttgtt
     5821 ttattaaatt cagttgttaa aataccacta ttataattct tactaagttt aattgacttt
     5881 ataagtgcta atgcatactc cttcttatct tttaaagaac aatcagtcaa aacactttca
     5941 tcacaacata attcacaatc tagatttact ttattgctca ttacatatac aagtggatta
     6001 aaccaatata ttattctaac agacaaaact aaaaacttta ttaaaatatc tttattttta
     6061 aaatgcatta attcatgttt caaaatccaa gttagttcat ctttactata aggatagtct
     6121 ggtaagaata tgtaagattt aaataatccc atgcctgctg gacttatcaa ttcatcagaa
     6181 cctcttaatt caattttctt ttttatattt aattctttta acaagttttt gtagatacag
     6241 tttatatcat tatcttcaat atcataagat acatcaacaa ctagattttt aaatcttgta
     6301 tactttataa atgtataaac tgcaatgact atagttacaa ataaccataa ataagctaca
     6361 tacagcataa gattattatc tgtagaaata tcaatttgtg taatattatt tcctaatgca
     6421 ttttctttgg gttcttttac ttcatatact attgtataat taaatagaaa aagtaacatt
     6481 ctaaagacta ttatcaacca aatataataa ttgaatctct tactaaactt cttaaataaa
     6541 tatcttttca aaaataataa tagacaaata ccaagactac atacaatagt tgtctttata
     6601 agattttcaa aaacatatag catataatta ttcatccttt aaattatcaa aataactttc
     6661 tagaaaatct agcttatctt tacctatatt ttcatcatca tgtaatgctg aaattaaact
     6721 tctcaaagag tcatcatgta tattacttag gaaatccttt gtctcaaaac ttaaataatc
     6781 tttgtgtttt actcttattg tgtaatgtgt atatctgtct attttttgag catctaagaa
     6841 tcctcttttt accagcctag ataaaagtgt cagtgtggtg gtttgtttcc agccatattt
     6901 ttgttccata gcttcaataa catcttttga tgtcactgta acatctactt tccaaatgaa
     6961 tttcattact tttagttctg cttgtggtat ttttcttatc attatttaca cctccctcaa
     7021 aactcctgct accttaattc tacaacatgt gaatttttta gtcaaacact ttatgaaaaa
     7081 aatgtgaatt tttgtacttt ttgttaaatt tctaattttt ttacaatatt aaaagttaga
     7141 ttttaaaata tatctattta aatattttac tttttacata tttaattaaa atagtgtaga
     7201 atgttattta cacattaaaa ctatttaata aaaattccta tattttcaca caaggaatat
     7261 tataatactt ttttttaaaa taaactagag taatatctaa taaattttaa taacattcta
     7321 attatgcctt tatgctatta aaacatctat tttatactga ttatttacaa atatatctaa
     7381 attaattata aattttattg aataagactt ttataattat acctttcata aattataaaa
     7441 aagtactttt ataaaaaaat gtgcttttaa tatctactaa taaagttctt tattttaatt
     7501 aaaacataat tatattttag tattataatc ttttaatttt agcattatag tttatgtatt
     7561 ataccctaat atattttatt ttaaattact agttagtcac tcttttcggg ttatttatct
     7621 cctatatatt aaagtgtcac atctaaatag ttaaatcatt atcctctttt atctttattg
     7681 cctttacaaa tccatctgca attacaaaac tcataagaga agttataaaa tatacaaata
     7741 ctggaacagt aaaataaaat ccaaatccta aatctagaaa tctcattcct tttccagtag
     7801 taccaaaagt tgaaataaac tcaattagag agtttaaaag caaaagatat ccaataatcc
     7861 taaatctttt tacattctct tttacaaata ggctatattc agaactacct aatacttcta
     7921 tcaatgattt tataatgata aaatatgata cacctaaaat aaacattaat attccataaa
     7981 tagtaccttg tagagttgct tctccactaa aacagaggta cataaaactt ttaaatcctc
     8041 ctgcaacaat tactaatcct aaaagaaaaa ataaaatttg taatatacca cttagtaaat
     8101 tttttataag tttattagac atcatgccaa ctcctttaaa atattttata tatagtataa
     8161 tacattatat tatatcgttt ttcaataaaa atattataat taacaatata tttttattgt
     8221 taattatgca aataaaaaag agtataataa aagcctttaa aatacatttt tttcttattt
     8281 taaaggcttt ttatattcta catttttatt ttctatatta tatcctttga taatcgttat
     8341 atctaaaata gaccttctta ccctaaatat aagtatcttt ataactagaa tagtccatta
     8401 caacagcacc tacatattaa tccactgata cctctttatt atcaatatct aaaattgaaa
     8461 ttttacaatt cccacccaat ttttcttgaa ctattttagc taattcattt aaagcatttt
     8521 caaattcttt aaatctactt tcatctacta attcaatgca taaaaaggca ttgttagtat
     8581 cttcagtaag cattgttctc actgcttcac gccaattcca acatctacaa atcgctccaa
     8641 catcatcttt ataaattatt tctccttcat atggaaatga attttcatct gtccctagtg
     8701 ggataaactc ctcattacca attgctctag ttagcctaat atctcctata aatttatcta
     8761 tatcctcccc tccacaaggt aatgcatatt ttaatgagat aaaattgtag atatccacta
     8821 aagggttaat agttcctata ttatttccat tatgaactct ttttaataat gcttcaatag
     8881 aagaccttgc tccttttttc gttttaaatt ttttaaatgc ttctctccat actttaatca
     8941 cttggttgtt gctaaattct gagtcctcca agtattttaa tgcttcttct tctcccttca
     9001 aaattatttt cttatagtct tcatctttta tagagttatc tatatcatta caaataacaa
     9061 ctccaatttt tgcactagga aatagattcc aaaatgcatc ctcaataaca aattttttca
     9121 ttagaaaacc tcctcaaatt taaaatatgt aaaaataaaa aagcctatag aaatattatt
     9181 aaatatctcc caggctttta tccttccgtg tacacaacaa ttgtgcgttt tctcttggac
     9241 ctgaccatta taaaatgcgg aaccctagaa aactaaatta taagtttttt aatttacaaa
     9301 atacaattaa attttagcat aatgtagtat ttaaaacaat attatattat ctgatttgta
     9361 cattaaaaca atttgctatt aaattataat tatggtggca aatgggtggc aaatcacctt
     9421 ttttattaca ttttcgtttg tttaaactat tgaaaatact atattcttac aattttaatc
     9481 aatttcagat ttaaatggag tgtcatcagc ttttgctatt ctatactcct tatcagttat
     9541 ataaccaagc tgatgcatct tatacagtac aatcacttgt ctcttcttag cctctccatg
     9601 gtcaatatac cttgcaggat tatttgtcat accagctaac atagcacact cagctaaatt
     9661 taattcacta acttttttac cgaagtagac ttcagctccc tttgcagctc catatgcatt
     9721 tttacctaga tacatattat ttaaatatgc ttcaagaatt tcatccttag tcataatctt
     9781 attcatctgc ttagcattat acatatccct tattttccgc ttcatagttt tatcattact
     9841 agtaagcagg ttttttgaaa cttgcatatc tatagtactt gcaccttgtg ttgtatctgt
     9901 aaacacattg tttaatactg acctaactag agaaataaca tctactcctt tatgcttata
     9961 aaatctctca tcttctatgg aaactattgc atgttttaaa tcatttggca tttgttttat
    10021 acttacaacc tcactactta tatatttaga cctaattaac tttttagtaa cttctggtga
    10081 cccttttata gctgaaactg taaatattgc acctgccact gaaaatataa ttagtgcaac
    10141 taacataata gataataatg ccctaactat tctaatcctt ttttgttttt ttcttttttt
    10201 actttttaat tttttctctc tttgtttata ctcgactctt cttctttctc tttgattgta
    10261 atctgtattt aaaggtctta cattatctct tgtaaaacta tctctatctc tttttataag
    10321 attctgtgaa tctacttttt cactcattct tttactggaa cttgtattag gacttttatt
    10381 ttttttattt gccgaagtat aagaatgttt agatttttta ttactatctt tgttgttact
    10441 aattttttta cgtcttattt tattattatc attatcattg taataaccca ttttagtctc
    10501 ccttcttcat ataaggtaca ttatacattg ttctacaaaa taaatcaaag aacaaaattg
    10561 taagcttaag gggcaatttt ataaaggata ttttcactaa ttttctctat atttataatt
    10621 aatattcatc ttttattttc aaaaatagtt ttgcagttgc taatgtatca ctgtcagctc
    10681 tatgagcatt tatattctct atgttgtaat aagcacaagc tgtttcaagt ttcttgtttt
    10741 ttcctttata acttttacat ttttttaata actctactgt acatatataa ttgtttattg
    10801 gttctaaatc taacattcta agatagtaat ttaaaaattt taaatcaaat ttcgcattgt
    10861 gtgcaattat agttctatca cctatgtatt ttctaaatct aggtaaaact aattctagtg
    10921 gttcttcatt ttctaccatt tcattactta tatgtgtcaa ttctgttata aatgaagaaa
    10981 ttatcccctt aggttttatc aaccttgaat agttttttac aatttgttca ttttttattt
    11041 ctgttattcc tatttctatt atttcacaac ctttatatgg atctaatcct gtagtttcta
    11101 aatccacaac tacatactct ttcatatctc ttctccttat tattaaatgg atatatttat
    11161 attctatatt tatgtaatag actaatcaat acttaatttt atatgatata ggaagatttt
    11221 acaaattaca acatagatat atcctatatt ccatcataaa taaagatttt tttattagaa
    11281 taattaaact tttaatttat tgttatttaa tctattttga taaacattat ttattttatt
    11341 attatttaaa tctttaaaat ctaaactttt acattgttca tcatcttccc atattcctgc
    11401 ttgtttattt ccatcatttt tatataatac acccttacca tttttcttat tatctaaaaa
    11461 atatccctta taaatgtcat tattgggata tgttaatttt cccaaaccat tttttaatcc
    11521 gtatttaaat tcacctgtat atattgaacc atctctataa gtatattttc ctattccatg
    11581 catcttgtca tctttccata atccttcata cttttcctta cttgaaaaaa tatatattcc
    11641 aaatccattt ttctttccat caacaaactc acctttatat aaatcaccat tatcgtattt
    11701 aaatactttt tcttccttta atttcttatt gttactctta tttttattat tattgttatc
    11761 ctttatatgt atttcttctc ttctggcttc aataaaatct ctatcatacc taaatccgtt
    11821 tcttgattta attttttgat taatcttctt cttattaata aatactctag ctagttgagt
    11881 aaatataaat acagatgata agcatataaa tacacatagt attgttgtaa aataactagt
    11941 tatattttcc ataaaaaatc accctttaaa aaatttattt aaaataccta atataatata
    12001 tatttttatt aaatgttatt tatactttta tagtactata ttgaataaaa ttaactttga
    12061 aattatttac attaaaataa atcaaataca aatgccataa attaagtgtt tctagttagc
    12121 ataaaaatac ttataaagta tactcaaata tttcaaataa atacttttat tcaaataaat
    12181 ctctacttat ataagtgctt atataaataa aaagatgaac tatagtaaat atagttcatc
    12241 ttttttataa tagtatttat ttaaaattaa tatttattta gttactagca tctacttaga
    12301 tatcagataa gaaagcacag tcatttactt ataataagtt cttttcatat attttttatt
    12361 ataattattc ttttacaaga acttttataa tttctgaaat gtacatagta tggtagtctt
    12421 tctctggata ccatttttta tcattttctt tagcatcaaa gttttctggt ggcatattat
    12481 catgatatag ctttttacat actataatca tattagcttc ttcaaaagct accgtatcat
    12541 ccacaaaata tggtgtaagt cctgcttttt ctattttatt tatatctcta ccagaaatag
    12601 taccacaaat atttaaagcc tctctatacg tttcatcaaa gaaggcaact gtaaatgtat
    12661 cattactatc tacaaattct tttgtatatc tctgtggtct tatgtaagtt gtaacaacat
    12721 ttttacccca atatactcca acaccacccc agctagcagt cattgtgtta aacttttctg
    12781 aatcaccagc tgttataagt aaccattctt tgccaatctt agtaaatgga ttaaactgta
    12841 attcctcaat ttttacttct ctaaaaccca tgacttcatc ctacccttca ttttttaatt
    12901 atataaatta attgttaaaa atttgaatat atgtactctt ataatactga cttttgattg
    12961 tcctacataa ttcatgtaaa ttataataca acaaatcaat tactttcgca ataagtagtt
    13021 ttcatatttt ataagtgtaa aatatagata aaatatattg attataaagt atataatata
    13081 tttttaaacc taaagcaata tacaataaaa aaatgtagaa agtaagtatc tctctacatt
    13141 ttttattgta tattattttt atattaattt aattttatct tgattcagtt ttataaaaaa
    13201 ttgttataat tgtcaagttc tactctatta tttataattt cttatatctt attaacaaca
    13261 tttaagttat tacatttatt tatatatatt ttttcattat ctaagtcttc atcaaacatt
    13321 tttattatat tttttatctc atacttgtac tcatcttcat tcattctata aagcattaaa
    13381 tcttctagta catctttcat atcgaagtac acatcttcta ataaataaaa atagccttcc
    13441 tctatatctt tcaatttatc tatagtatcc atttttttac ttatatcttt cataatttct
    13501 aaattttgta tatttacatc tatgattgtt aataagtaca ttctcacagt ttttattatt
    13561 tcaacagaaa aatctacaat attataattt ccttcttttt tatataatga ctccttaaat
    13621 ttgttaaaac aattatctaa attagaattt atatcgttaa atggtggtct tattatgtca
    13681 cgtattatta aaagattttg tatatctaca ttatttgtga ttgcctcatc caaaataaat
    13741 aaattatatg catcatttaa tgggtcatgg gcatctccac taaactctaa gttaacaaat
    13801 tcaagtaaat ttttcaatga tatatagttc atacatctca taccacaatt tatatatttt
    13861 tcttttatat ctacaaataa atctctaatg ttatttacaa accttggatg gttatttttt
    13921 ttagcacttc tcatatctgt gttattgaaa catgtcaaat ccaaattacc aaaagtatat
    13981 attcctttaa tatcagaaaa tatgccaagc cattttttaa actttctcat gacctcttca
    14041 taacttggtg cactcttcaa ttcttcagaa gatatatgtg ttaattcttg tatatgagga
    14101 tacaactcct cattacttac tggtcttatt aaagatttaa atttatcaat attttttgtt
    14161 ttttcatcat acataactgc tccgattgca attatatcag aattaaatac tgctcttttt
    14221 gatttagaat ttggcatatt catttcaaaa tctatatata ctcttttcaa tataaacacc
    14281 ctttccaatt gtttatagtg attcttttta actattttta ttcaaaattt tctaagaaag
    14341 aatgtttctc cccatctttt tgccaaccaa gtactgaatc aagatttaca ttttctgctg
    14401 ccttaaatat agatttttct acatttttaa aatttgattc taagctcttt attaagtctt
    14461 ttatctcata tcttttatta cctgtttttt tagcagcaac catacatgca caatttaatg
    14521 gccatatacc actattttga ataaatctta taatatgttc ttctcttata taataaagtg
    14581 gtcttataat ttttatacct tcaaaattag tagaattaag tttaggaagc attgttttaa
    14641 aatttccagc acacaataaa ttaagcattg ttgtctctat tacatcatca taatgatgac
    14701 ctaatgcaag tttgttacac cctaattctt ctgcctttga atataatgct cctctcctca
    14761 ttcttgcaca catatagcat ggataatctt ttgctatttc atctgctatc tcaaatattc
    14821 ttgaatcaaa taaatgtatt ggtatattta gatactcaca attatctata agtaattgtc
    14881 ttatatttgc atgatatcca gggtccatag caataaattc aacatcaaaa ttaacttgtc
    14941 catgtttttt taactcttga aacattttag ccataagaat actgtctttt ccaccagaaa
    15001 tcgctacagc tatcttatca ccttcttcaa ccaatttata atctcttatt gccttcataa
    15061 acttagacca taaatttttt ctatattttt ttattatact tttttctata tctcttactg
    15121 gaagtctttc ctcaaaagga actataattt cgcagccttt tcctgatagt tcactcatct
    15181 aatcacctcg tatatttatg ttaataatat tttacaaaaa agtctacctt catccacaaa
    15241 atactataat ttttacttta attttactaa ataatttata gtttacaata acacataaac
    15301 ttataataac ataaataacc tctttctttt attatctttt ttatttttct catttaatat
    15361 tttattatta gtaacgattt ttaaatgatt gaatattata cactagatag agttacctat
    15421 ctatttacaa caaggaggtt ttcatcttgg aaaataagac tagagatatc aaaaaaaatt
    15481 gtggtccatc tttggctaga ccatacatta ataatcaaat tttcacagaa atgtactgcc
    15541 tttctgatgc attaaaattt ggaactatat ttccagaact aaacttacta gagtctgaaa
    15601 tgtacaacaa agaattatat gctaagccaa aaaaatatag aggaggtaga agataatgaa
    15661 agactcatct agagctgaac ttatgagaaa agttcaggaa acatcttttg catgtgttga
    15721 tatgaactta tatttagaca atcaccctga tgataaaaat gctatcaaca cttataattc
    15781 attatgtaat caatttgcgc aagctagata tgcttacgaa aataaatacg gtcctttaac
    15841 taactttggg tatgctccaa gtagatgccc ttggcaatgg gctgaccaac cttggccttg
    15901 ggacagagaa tttaattatt agacatcaag tattggagga ttgaaaattc atgtggatat
    15961 atcagaaaac tatacaacac ccagttaata taaaaacttg tgaccctaga atggctaaat
    16021 ttcttataac tcaatttggt gggccaaatg gggaacttgc tgcatcttta agatatttaa
    16081 gccaaagata tacaatgcct actggtaata tgcgtgcact tttaacagat attggtacag
    16141 aagaactagc tcacgttgag cttatatgta ctatggttta tcagttaact tctgatgcaa
    16201 gcccagaaga gttaaaagct gcaggtcttg gttcaaacta tgctcaaaat ggatatggaa
    16261 tttatccaac agattcaaat ggtgttccat ttgatgtaag acctatagca gttatgtcaa
    16321 atcccgtaac cgatttacat gaggatatgg cagctgaaca aaaagcactt gcaacttatt
    16381 atcaacttat aaacctaaca gatgacgttg atgttataga tgtattaaaa ttcttgggtc
    16441 aaagagaaat aattcactat caaagatttg gtgaagcttt aatggatgct tacgagttag
    16501 aagaatctca aaaaatgttc taaaattttt atttgtataa ctattattat ttgataattt
    16561 ataatttact gttgtgttaa aatttataaa aaatataaat ataatttatt ttctataaac
    16621 agagaaaata aataaaaagc aggtatcaat caaatagtaa catgtattat actatacatt
    16681 actatcaata ttgtacctgc tttcatatta taagcaataa agaaaaatct atttattagg
    16741 ttttataata aaaacaatta taaaactctt cttgcattta catatctact tgaatagtag
    16801 ctactattta tattagatat tgttactttt tttgatgaac ctgaagatgc atgtatcata
    16861 tctccatttc ctatgtatat tccaacatga cttacagaac cattatttga accttgtgta
    16921 tcaaagaata ctaaatctcc acttctaagg tctcctctat ttacatatgt tccatactta
    16981 ctttggtctc tagatactct tggtatacta actcctacag attttttcat aacgtactgt
    17041 gtgaatccag aacagtcaaa actatttgga ccttctgctc cccatacata tggttttcca
    17101 agtagtgtct ttgcaaaact tattacacta tcagctcctt gacttggaga attagtcgaa
    17161 taagatggaa ttgaagtatc aacagaacct ttttcagcaa ggtattgact tgacacatat
    17221 ccagtttgat tgccataact tacttttgtc catcctccac tttcagaaat acttccaacc
    17281 tcagtaccat aacttaatgt agctatttta gaatgacttg tacctggtcc tgttctaacg
    17341 ttcaatgact ttgctgttac aacctttgta ccctttacaa ggtcatttga actgttttca
    17401 gcattttcat ttgtagagtc atttacacta gttcctaaat atttacttga aacataacct
    17461 actctaccat tagaacttat ttttgaccat ccatttgact cagatatgta tccgacttca
    17521 gtcccatatc ctagtgttga tattttagaa ctacttgtac ttggtcctgt tctaaaattt
    17581 aatccttttg ctgttacaac ttttgtcgac ttaactgaag tatcactact ttcattgcta
    17641 cttccaaggc tatttattgc tacataattt ccatgcacat aacctgtgtt tccattatat
    17701 ttaactttta cccaagaacc ttcttttcct acgtactcaa ctttatcacc tttgtaaagt
    17761 ttccccattg attcatggtt tgtacctggt ccttttctaa aatttaccgc attccctgtt
    17821 attgttctgc tttctatact cacactctct acttcagact cattagcata tgctaaattc
    17881 cccatagtag gcattattat cgcagttgcc attatactgg ctgctattct cttttgatta
    17941 aaattcataa ctttccactc atctcctctt ttctactatc tttatttcac ttcaaaatat
    18001 aaaagaaata attgacacta tcaaaatatc aattatttct tttatattaa tattattaca
    18061 aatttgtaac tatttgtcta tagtaatatt tgcttaccat aaattaccat gtataaattt
    18121 taatctttaa tagcctgtaa tttagtaata tagccatctt ttaccttttt taaaaatggc
    18181 tatatttttt aacttttttg taacttttta aaatccagtt gagccaaacc caccttttcc
    18241 tctttcggag tcacttaatt cttttacttc ttctatgtta atatcataga taggttttac
    18301 tatcatttga gcaattttca tatgcttttc aaccttaaaa tcatttttac catgatttat
    18361 taatataatt ttaagctctc ctctgtatcc ttcgtcaata gttcctggtg tatttaatac
    18421 agtaacagaa tgctttaagg caagcccact tctaggtctt acctgcgctt ctgtcatagt
    18481 aggaagctct atacatatcc cagttttgat aagtttagtc tctccaggag gtattacaac
    18541 ctcttctata gaatacaaat ccataccagc atcacctttg tgagcaaaat taggtattat
    18601 agcatcatca tttaattttt ttacttttaa attgtacatc ttatatctcc tttcaacttt
    18661 ctataaatat tataacttaa atttcgacct cttgaagttt tttatttttt tgtggtaata
    18721 taattattag tgttttaaag gaggattttt tatgaaactt gtacttgctg agaaaccatc
    18781 tgtagcaaaa actatagcat catttttagg tgcaaagacc agacaagatg gttactttga
    18841 aggaaatgat tatataatta cttatgcagt tggacactta gtatcattat atgatatgaa
    18901 ggattatgat aaagataaat actctggctc ttggaaaatg aacaatttcc catttgttcc
    18961 tgaggataag tttaaattta agattgatag ttctaaaact aaacaattca acactgtaaa
    19021 aaagcttttg aatagaaaag atgtagaata tgtaataaat gccactgaca atgaccgaga
    19081 aggagaactt atagcatttt taatattttt actggcaaaa aataaaaaac cagtaaaaag
    19141 aatcttggta aatgaatgga caccagaaga tattacaaga ggtataaaaa acctaaaaga
    19201 tgaagatgaa atgagaaatc ttcaagctgc tggatatact aggcttatta ctgactggtt
    19261 gattggaata aatttcactt ctgttgctac attgaaatat ggaaatggga aactattaaa
    19321 cataggtagg gtaattcttc caacagttaa attagtctat gatagagata tggaaatact
    19381 aaactttgtt cctaaaactt attatgaaat agaagggcat tttaaagctg aagctggtga
    19441 atataaaggt aaatttgtta agggtaaaga aagtaaattt gataaacttg aagatgcaaa
    19501 taaaattata gcttcaatta catctgaaac tggtaaaata ctagataaaa aagttactat
    19561 gtcaaaggaa tatgcaccaa aactttttag tttgacatca cttcaaggat atataacttc
    19621 taagtattcc aattttacat ctgataaggt tttaaatgtc tgtcaatctc tctatgaggg
    19681 taatggtaag ggtggataca taacttatcc tagaactgat tccattttct tagaagaaag
    19741 tttggcttca aaagcttctc aaactttaga taaattaaag gttggtcttg aatatgaaaa
    19801 taaaattaaa ttttctaaaa ctaaaagagt ttttgattct tctaaagtag actcccatag
    19861 tgctataatt ccaacttata taattccaaa aagtttatct aaggatgaac aattagttta
    19921 tgatgccata aaagatagat ttgtagcaaa ctttatgcct cctgctgaat atgagaatac
    19981 agaaattaag actgaagtag ataattgtac tttcttaaca aaaggtaagg tacttaaatc
    20041 aaaaggatat cttgaagtat ataataagga agaaaaaaac gatttacttc cacttgtaaa
    20101 taaagatgat gttgtagatg tgttagaaat aaaaccatta actaagcaaa ctactccacc
    20161 taaaccatat actgaggaca cccttttaaa ggctatgaaa aattgtggta aaaatgtgcc
    20221 tgaagaagat acaacagtgc tatctggata ttcgattgga acatcagcca cacgtgctga
    20281 tgtgttaaag aagataagtc aagtaggcta tgtaaagaaa aaagggaaat cttattctat
    20341 aacagacctt gggaaaaatt tagttgaaat ttttcctgtt aaagacttat ttgatgtaga
    20401 ttatactgga aaacttgaaa aaagtttaag cgatattcaa aaaggaaagt atacaagaaa
    20461 agaatatctt actaatatca ttagttttat atatcaaaat gtcaatatta taaaacaaga
    20521 tgcttcaaaa aatataaaca cagaagcata tactttcgat tcaaaaacta aaaaatttac
    20581 taaaacaaaa gaaaaaaaac agaaaaaaga tgtaactaat actgaaaaag aagttgctat
    20641 atcaaaggat tctaataaca aaaaagaagt taaaaatggt gatgaaaatc aatctcttgg
    20701 caaatgcccc atttgtcaag gtgatgtact agaatttgat aaaggctttg cttgtaaaaa
    20761 tcataaagaa tgtaaatttg ttatttggaa aaatgataag tatttaagtc tttataaaaa
    20821 gaaagttaac aaaacaatgg tcaaaaatat tttaaaaaaa ggtgaaacta aagtaaaatc
    20881 tttaactgct aaaaacggta ataaatttga tgctacatta aaatatgata aaaatccaga
    20941 tactggctat ttcaattgga aaatagagtt tgacaactaa atattcataa gaaaagaaat
    21001 agcagtagta taataatcta tattatatta ctgctatttc ttttcttatg aagttttaac
    21061 ttttttaata gtgactttta caatcacact ctaacctaat ttctttacta tttctgataa
    21121 ctttaatgta tgttcatcta ataaagttag ttcctcttca gaaagattag ataatttttt
    21181 tactagagat tctttgagaa tagcttttac tgcatcaaat aatttaaatg ctttatctgt
    21241 taattcaacc ctaagaatcc ttctatcttt tgggtcagga aatttattga ctaaaccatg
    21301 ttccactaat ctgtcaataa tcggagtcat atttgatttt aaaattccta aattagaagc
    21361 tatttgagaa attgatgatg aatttgatgt cataagataa agaattacct tagcatgtga
    21421 tggagccatt ggacattctt caaaataagc tttcattata tcagagttat tttgaaactt
    21481 ttttaacaaa tcgctttctt taaatatatt attttcaagc acaaataaaa aatctaaaaa
    21541 agagtccgct attttaagta tattgttgtt atccatattt gtaacatccc ttcaatagat
    21601 aatataataa aacattgttg tttaatatag tataaattat aaactattaa taaatttaaa
    21661 acaagaaaaa gttattgact cataataatt ataaatttat aatcaaatta gagaattata
    21721 aattgccaat aaagggaagt tttttaatta gtctaaaact aaacttaaat tataagacac
    21781 tttaaattct acaacaagct agtgtgcaat atataatagg aggagatatg aaaagatatt
    21841 taatagtttt cttaatgtgt agttcactgt ttttagttgg atgtggaaaa acagaagaat
    21901 ctgaacctga gaaaccaata gcagtttctg ttcaaaaagc aataggtgga gaaattgaaa
    21961 acacaaattc tttctcagga actacaaagg ttaaagatga aacagctgtt actgcacaga
    22021 ctgttggcac agttcaagaa gtgtatgtaa aacttgggca aaatgtaaga aaaggagatg
    22081 aattattgag tataagcagt ccagagctag aaaatagtgt aaagcaaagt aaagcctcac
    22141 tagatttagc aaaagcaagt tattcaagtg ccactggtgg ttcattagag gcacaagtaa
    22201 atcaggcaaa aacagctctt gacaatgcaa agattcaata tgaggagtct caaagaaatt
    22261 atgacaataa taagattctt tatgaacagg aagtcattag tttagaccaa tttaaaaaaa
    22321 tagagttttc tttagagcaa acaaaacaac agttagattc tgctcaaaga gcatacgata
    22381 cagcaacttc aaaaagtata cctcaagcta aagcacttgc taaaaaacag cttgaccaag
    22441 ctcaagtatc atataattta gcaatgagta atttagacaa attaacatta acatctccag
    22501 tagatggtac aataacagct aaaaactttg attcaaagga aatgataaca caatcacaac
    22561 cagcttttat tatttctaat cctaatatac tagaagttga tttaaatgta gcagaatcag
    22621 atataggtaa atttaagaaa gatggaaatg tagatgttat aattgaagac caaaggattt
    22681 taggaaaaat agattatgta ccttcagtag ttgaccctca gacatcttta tatcctgtta
    22741 aagtacttgt aaataataca aacaacaaat ttaaggcagg tatgtctgct caagtaaact
    22801 taagtgttga aaaagaaaat ggtgctgtta cagtacctaa aaaagcaata tttgaagaaa
    22861 atggtaaaaa atatgtatac atagcaacaa aagacaatat agcaaagaaa cacttggttc
    22921 aaactggaat tgtaacagag gataaaatag aaattaaaag tggtgtaagt gataaagata
    22981 cagtgattat tggagggata agtcttattt ctgacggaac taagatattt cctgtagaaa
    23041 aggagaagta gactatgaat ttaacacaga cttccgttaa acgtcctctc acaatcataa
    23101 tggtcttttt agtattaata gtttttggtg gtattggata taaaaaaatg tcaataaatc
    23161 taatgcctga tatagaaata ccagttgtaa tggtcatgac tacttggaca ggtgctggtc
    23221 ctcaagacgt tgatgaacaa gttagtcaaa aagttgatga aagtttatct gccgtttcaa
    23281 atgtaaaatc tactatatca agttcacaag aaagtgtttc tatggtagtt gctcagtttg
    23341 aatttggaac taatttggat gaaataatga atgatgttag gtctaaagtt gatgcattac
    23401 agaccagcct cccagatgat gcagctaaac caacagtttt aaagctggat atgaatgcac
    23461 aggctatagg tcaacttgtc atatctggag gaaatgaaaa tagttcacaa gccttaagaa
    23521 aatacgctga agatgtaatt cagcctaaaa tagaatccat agatggtgtt acttcagcag
    23581 accttaaagg tggaaaaaaa gcacaggtta atgtaatagc tgacccagct gttctttcaa
    23641 attatggagt tagtttatcc actataaaag gtgtcttatc ctctagtaat aaaacattcc
    23701 cttatggttc aattactcaa ggtgaggata aaatagtttt aagagcaatt gataaattag
    23761 aatccctaga tgatataaaa cagattcaaa ttcctgtaaa aggaggaaat acagttagat
    23821 tagataatct ttgtagtgta gattatggat atgcagacaa agatagtatt tatagataca
    23881 atggaaaaga cagtttggta atagatattt ctaaacaaca agatgccaac actgtaaaag
    23941 ttatgcagag tgcatacaaa tacgtagatg aattgaataa ggaaaatcct caatttaaaa
    24001 ttaaaattgc taatgataca agttcataca taagtgaatc aataaacagt gtaatgagca
    24061 acttgcttat aagtgctgtt atcgcattta ttgtaatatt tgctttccta aaaagtgtaa
    24121 gagcttcact agttgttgca gttgcaatac caatttctat aataggtgct atagcaattc
    24181 tctactttac tggtgaaagt ttaaatctca ttactgcaag ttcattggta atttcagttg
    24241 gtatggttgt tgataatgct acagttgtaa ttgaaaatat atttaaatat aggaaaagtg
    24301 gcagattgag tcttgatgat tgtgctattg agggaacaag aactgtaaca aatgcaatac
    24361 ttgcatcaac attgaccacg atagcaatat tcttacctat catgtttaca gaaggtatag
    24421 ctaaaataac ttttggggca ttaggtaaaa cactaatagc ttcactagca ttctccttta
    24481 taggtgcaat tacactcgtt cctagtgtat ttgcaaaatt aagtagagga aaaaatagtc
    24541 aaaagatgca agaaaaagat agtcctatat ttgataaggt aagtgaagca tataaaaaat
    24601 tattaagtgt atgtttgaga catcaacgct tagttgtaat atcaagttta cttatttttg
    24661 tagcttcctt atttggaatg ggatttatag gtatggactt tatgcctgca gcagacaagg
    24721 gtgaattatc tatttctata gaacttccaa aaggtcttag cctagaatcc aatgattact
    24781 atgtatctat gactgagaaa aaagtctcag atattccaga aattaaaact ttaataacaa
    24841 ctttgacatc agattcaaat aatagtaaag caagtatagc aattgaatta gaatctcaaa
    24901 aaaatagaaa aagaactact gatgaaatag aaaaagagat aattgataga gtagctactg
    24961 taccagattg taaaataaat gtaagtcaaa acagtagtgt tatgggtgga gctggaggag
    25021 cagacttcac attagaaatg aaaggtcctg atttagatgt attaaaaata ctgggaaaag
    25081 aagctgaaaa agaatttagc tctataaaag gatttagaaa tgttgaaact tctcttacag
    25141 atacaacaca agaagctcaa tttactatag ataaacataa ggctcaagaa tatggtgtaa
    25201 atactgctga aattgcaggc atgttacgta cagcaataaa tggtgactcc gtaaccactg
    25261 ctactattga tgattacaaa gtggatgtaa acctaaaatt taaagcagat actattgata
    25321 gcttagaaga tataaagcaa ctaaaagtaa actctgcaac tggaaaagaa gttcctcttg
    25381 gtgctttttc agatataaaa atggcagatg gtctacaatc tatatctagg actgatggag
    25441 atttttctgt aaatataact gctacacttg acaatttaga tgctggtact gctacaaaac
    25501 tagcactaga aaaaacgaat aaaatggtaa ttcctaaaga ttactctata ggtgttggtg
    25561 gtgaaacaga aatgatgaat gaatctatgg caagtcttgg attttcaatg gtcatagcta
    25621 tagcattagt ttatatggta atggtagctc agtttgaatc atttagtaaa ccatttataa
    25681 tcatgttctg tgttccattt gcattcgttg gagttgtgct ttcgcttcta gttagtggtc
    25741 aaagtttaag tactgtcggt atgctaggta taatcttact tatcggtatt gttgttaata
    25801 atggtatagt tcttattgac tacatagagc aacttagaaa aacaaatcgt aacaatgatt
    25861 taattggttt ggtttcaatt ggttgtgcag caagattaag accagtctta atgactacag
    25921 caacaacaat tttaggtatg ttgccaacag cactatctct tggtgaaggt ggagaaacta
    25981 tgcaaccact agccatagtt ataatgggtg gtctaactgt atctacactt ataactttgg
    26041 tgcttatacc tactatatac ttaatatttg ataaatggga aaataagttt tcagacaaaa
    26101 tgcctaaaat atttggtaag ataacagata aaataggaag tataaaacgt aaaataataa
    26161 agaaaccaaa attgaaagct aaagtttaaa tagaatggag ggtgattgta ttgaataaaa
    26221 aaatgagcaa aatagttgca attggctgtg gtgttggtat aataactgcc aatttaatcc
    26281 cagtttacgc agataataat acttcttcta taaacaaagt tgataattct attttaagtg
    26341 actcaaataa aagaacatct gaaaaggaaa ttttgactgc tagagaagct gttagtgctg
    26401 cacttaaaaa tagtgaaaaa ttaaaaatga aatcagaaga aataaaaatg ttaaaagaaa
    26461 agttagaagt acaagatgag tttgatagtt ttactggaag tgacaactcg tttccatacg
    26521 accaaattgg acttcttaaa aatcaaagtg aacaggctaa aggctttatg gaggaccaaa
    26581 tagcaaatga tattactaat aaatttaacg atttagtttc aagagaaaat gagctagaca
    26641 agataaaaaa caatcttgaa ataaaaacta aagaaattaa agatatgaaa ttaaaaaaag
    26701 atttagggtt agtaacatct ttagaaactg aatcagctga acttgaactt caaacactac
    26761 aaaatactca aaaagctaaa cttcaagaac taaaaaacaa tcaagactac tttaagttgt
    26821 tgactaatat agatttaaat aattatcaat tggataaaga atatagattt gaatctttta
    26881 gagtaggtgg ctcagttgat tcatatatgg aaggtaaggt taatgaatat ttaaaatacg
    26941 accaattgat tttagaacgt acagaagaaa gctttaatga taaagatgag aacaaagcag
    27001 atttaccaga tagacctaat cttacaagac cagttgctcc tacaaaacca gagcaaggta
    27061 acctaactga tgatgaatat aaggttctta cggataagta tgaaaaagac tacaagagat
    27121 atgaaaaaga agttgaagca tacaatcttg aaagacagac ttatgctgct ggccttacta
    27181 cttatgcaaa ttatcttcaa caaaaattta atactgaaaa tggtctagta acattagaag
    27241 acagtaaaaa agctcttaaa aaagggttaa ttgatagcta tgctcaatta cttgctttag
    27301 aagatacaat tcagattact aaaaaacaac ttgatttatc agaaaaacaa ttaaaaaata
    27361 ctaaattaag atatgattta ggattaattg ctctaactga ttataaaaaa caagtggtaa
    27421 gtaatcaaga tgctaaaaat agctatgaca ctcttattgt gaattataac tcactaaaaa
    27481 atggtataga aaaaccttgg atacttaata ctggaaaata attctggtaa atagaaagat
    27541 tactttaaca tacgtttgat taaaaaatag ttatgcacac tcgtggcttt agtcatggaa
    27601 gattcagaag gcaaataata gaaataggtt agtaaaaata tatttactta taaaactgta
    27661 tacttttata gaggctatct caaaatagag ataagcctct tttttattgt ttaaattata
    27721 aaaatatatt tgattccata caaaaagagt gccttatgaa ctaaaaagtt cattttgaga
    27781 caccctcaaa agcttaactc taaatttaat tattttttat caaatgtctc atctatttta
    27841 catctcacca tgttaacaaa ttcagaaata ttatatcctc taagtttgca tccacattta
    27901 ggacaataat ccagtttcct agataccaaa gccctacaac taggttctgg acatcttatt
    27961 tttagactct catctgctac tttaaatcca catcgtgggc atatactacc tggacgtgat
    28021 gatacttcct ttccacattt aggacacttt gtcaacttta tcccctccag taaactcaat
    28081 ttaattgata gttgaaattt ctctctacaa taatatatgc aatataatta aatacgtttc
    28141 acttacaact atataagtta aatttttata ataaaaatcc cctatattca atttacaaat
    28201 acttaatttg atacattgaa caatagggga ttttattttt atttagttac atattttgca
    28261 gtctattatt atctaggatt ttttatagat gcttgagctg ctgcaagtct agcaattggc
    28321 actctaaatg gtgaacaaga tacatagtta agtcctacac tataacagaa ctctactgaa
    28381 gatggttctc ctccatgctc tccacatatt cctagtttta attctggttt aacttctcta
    28441 cctaatttag ctcccatctt aactaactta ccaacaccat tttggtctag tacttggaat
    28501 gggtcttttt ctaatatttc ttcatctaca tattgaccta agaatttacc agcatcatct
    28561 cttgaatatc caaatgccat ttgagttaag tcattagtac caaaactgaa gaagtctgct
    28621 tcttgtgcta tttcatcagc agttaaacaa gctctaggta tttctatcat agtacctaca
    28681 gtataaggaa cttctatacc ttcttctttt attatagcgt caacagtttc tactatcatt
    28741 tttcttatta tttttaactc atttacttct ccaactaatg gaaccattat ctctggagaa
    28801 actttaacac ctgctttgat tgcttctata gcaccttgta ttatagcttt agattgcatt
    28861 acacatattt caggataagt tattgcaagt ctacaacctc tgtgtccaag cattgggtta
    28921 aactcatcta aatcaactat tctcttctta atatcactta cttttattcc catagatttt
    28981 gaaagttctt ctatagtctc atcatcatga ggcaaaaatt catgtagtgg tggatctagt
    29041 aatcttatat taactggttt tccatccata actttaaata actctacaaa atcttctctt
    29101 tgcattggta atattttttc aagagctttt tctctttgtt ctactgtatt agataatatc
    29161 atttctctaa ctgctggcaa tctagcttca tcaaagaaca tatgctcagt tctacataga
    29221 cctatacctt ctgcaccaaa ctctatagct gcacgagcat ctctaggatt atctgcatta
    29281 gttctaacca tcatacattt gtgtttgtct acccagttca ttaatttttc aaaatttcca
    29341 gttaaagata cttctgtttt cttaacattt cctaggtata catttcctgt agaaccatct
    29401 atagaaatgt attctccttc ttttataact acatcatcaa gtgctcttat ttctttatta
    29461 aactcatcaa cttttatttc tccacatcca gcaacacaac atttacccat acctctagca
    29521 acaactgctg catgtgatgt cattccacct ctagctgtaa ggattccttc tgctttaacc
    29581 attccttcta tatcttctgg agatgtctct agtctaacta aaactacttt ttctcctttt
    29641 tcatttgctt ttactacatc atcagcattg aaataaactt taccacttgc tgcacctggt
    29701 gatgctggta aaccttttgc tataaccttg gcttctttta atgccttatc ttcaaatttt
    29761 ggatgtaata attggtctaa ttgattaggc tcaattctca tgatagcctc tttttcatca
    29821 attattccag cttcaactaa atcaaccgct acatttattg ctgctgctgc tgttctctta
    29881 ccatttctag tttgtagtat atataatctt tcattttcta tagtaaactc tatatcttgc
    29941 atatctttat aatgaccttc aagtatatga gtaattttta caaattcatc gaatacagct
    30001 ggcattacat ctgcaagagt tgatatattt tgaggagttc ttatacctgc aacaacgtct
    30061 tcaccttgtg cattcattaa aaattcacca aataatttat tttctcctgt agctggattt
    30121 ctagtaaatg caacacctgt accactagtt tctcccatat taccaaatac cattgattga
    30181 atatttactg ctgttcctaa gttatgagct atatcattca atttacggta tacgattgca
    30241 cgaggattat tccatgatct aaatacagcc tctattgcaa gcattaattg ctcttttggg
    30301 tcttgtggga aatcattttt tatttctttt ttataaattg ctttaaattc ttttactatt
    30361 tcttttaaat catcagttgt aagttctgta tcaactgtgt atccctttgc ttcttttact
    30421 ctgtctaata cattttcaaa tttatatttt ggaacttcca tagcaacatc agaaaacatt
    30481 tgtatgaatc ttctgtaact atcatatgca aatctttcat tttgtgtagc ctctgctaag
    30541 ccaacaacac tattgtcatt aagacctagg ttaagaattg tatccatcat tcctggcata
    30601 gagaatactg caccagaacg aactgatact aataatggat tcttattgca tcctaatgtt
    30661 ttatttaagt ctttttctaa agtagctaaa tgctcttcta tttcttttat tatctctgct
    30721 cttatacttt cattgttaac ataataatca ttacatgctt ctgttgttat agtgaatcca
    30781 ggagggacag gtaagcctat cttagtcatt tctgctaaat tggcaccttt acctcctagt
    30841 aaagatttca tgtctttgct tccttcacca aaactataaa catacttagt ttccattgtt
    30901 aaatccccca ttaatctttt tattttaatt tatatcattt ttattaatag acattattaa
    30961 atttctattt ctttgtatat ctttagacca ttttctttca ttatgtctaa aattatacct
    31021 gctgtttctt ctattgcctt atttgaaacg tttattactg ggcatccaat tcttttcatt
    31081 atctcttctg aataatctaa ctcctgaagt attctttcta aattagcgta gtttgcttta
    31141 ctggacaatc ctaaagcttt taatctttgg gttcttatct cattcagctt ttcaggtgaa
    31201 ttagtaagac ctattatttt tttagtatct atctcaaaca cttctttagg aattggtatt
    31261 tctggaacta atggaacatt agctactttt atatttttat tagctaaata catactcaaa
    31321 ggagttttag atgttcttga tattcccact aaaattatgt ctgcttgaag aacacctcta
    31381 gggtcttttc catcatcata tttcactgca aattctatag cttcaactct cttaaagtaa
    31441 gattcatcta attttctaat tataccagct tctcttttag gttttcttcc tgttctcttg
    31501 cttatttctc ttagtatatc tgtcattaaa tctatacaac taagaccttc tctttcgcaa
    31561 tatctttcaa caatactgca taattcttca tcaactaatg tatatacaat taaagcgttt
    31621 tcagcttttg cattctccaa agtttcaagt agtactcctt tattaatcat gtatggaaat
    31681 ctttttattt cataagtttc attcacataa aactgagaca tacatgcctt tgcaacttgt
    31741 tgtgcagtct cccctactga atctgatact gcatatataa ttaggttttt caccagcata
    31801 cctccttaat tgtcaactat ttctaagaat agcttagtta tgttggtttt tgatattctc
    31861 ccaacaactc tcatatgatt tttgtcttct cccttatatt caacaatcgg aatcgaatct
    31921 acttcatgtt ctattatttt tcttgaagct aataaaacac ttgctccttt agttaaagtg
    31981 actacatttg gagttcttgt cattatcata cctattggca ttttatttat atcagaacct
    32041 cctatagttg cttttagcaa gtcttttctg gaaacaactc cacataactc ttcattctca
    32101 tctataataa ctatactccc tacatcagat aaaaacatag tgactattac atcatatata
    32161 ctttcatcct tcttagctag tacaggcatg ctcattatat cctctactgt tttttctttt
    32221 acacttttac caattaaatt tatttcacta actcctgaat aaaaatatcc aacttttggt
    32281 cttgcgtcta atattcctgt cattgttaat atagctaaat cagatctaag tgtagcacga
    32341 gtcacattca agctggaggc aatactttca ctcgttattg gttcattttc cttaactata
    32401 tctataattt ttagttgtct ttcattaagc tgaataataa tcaccttctt tcattgtgct
    32461 atacttttta tcttttcgca tcttatatag tatattatat aactatatat accattctgt
    32521 aaacagattt tttattgaat acgatatatt ttttactaag ttctctcgct taaagatatt
    32581 tattatatat taatggggga tatttcttta attaatagaa ctatattagt attacagtta
    32641 atattataat acataattgg tcattttaat tcattttata ttaaaatttt taataatatt
    32701 atttcaatgt gaatataaaa ttgcagaact aattcaaaat aatttttacg actacaaata
    32761 acctataata tacttttaaa gaaagtatcc taacaagaat atataaaaat ttaaaagggt
    32821 tgatttaaaa ataaccatca acccttttta ctaatatcta tttatattac catcaaatct
    32881 tacccaaata ttttttcttg caattgtctt aaatgatata aagtagtatc tttttctatc
    32941 tctaccatat cgtaagttat aacttcacct tttttaatat cttttacaac tttagtcttt
    33001 ttacttatca aaccaatagg tacagcattc atagcctttg ctacatcgta tttttctata
    33061 gtaccatagc atgtatatgc tccatagcca tccataaact cacctttttt caaatctttc
    33121 ttagctatag tcataacttc tgctactagt ccagctttag gtactattgt agccttatgg
    33181 tctaagactg ccatagctgc tgataaagga gtctctaaac tacataaatg atatggtcta
    33241 tataatatgt aattaggtcc atcacccata cttaaatatt ttagttcatc attaactgct
    33301 tttaatttat gggctactac tacgaaaact ccaggtgcta taccatttac aaaatcaact
    33361 acaccataat tatctaatac tccaccttcg ctttttaatg catatttctt aggtacttca
    33421 ttaactgtag cttcaatacc atgaccacct cttacatcag gcacaaatcc agttgcatta
    33481 cacattaaag ccatttctac cattgtttta gttccttctt taaaagaagc tatcatatga
    33541 ggtgaagctc cttttctttc tgcttcttct ctaactgtat caggattaca atctaaatct
    33601 aatttattat ttttaccttt acctatcact ctaacttcaa accccattgc atctgcaaaa
    33661 tcaaataatt ccattactgc acctggctca tctcctgcag aacctgtaaa tattactcca
    33721 gcatcatctg ctaatttttt aagtattggt ccaacaacac aatcagtttc agcatttaac
    33781 ataactatat gttttttatt taaaatagag tttaatgcta tctctgcacc aattgcaata
    33841 cctccagttg catctataac tacatctatt gacttagttt tacaagccac aagaaaatca
    33901 ttacatgtca atacttttcc ttcttgtaat tttatttctg catccttttc atttgttaca
    33961 ttatctataa tttcttcatc tattcctgca tcagtaaaag ctttatgagc caactccaaa
    34021 tttatatcta caacaataga agcttcaata cctttcatat ttgccatttg gcttaccatt
    34081 ccatttccca tatgcccagc tcctataaga gctactttta tttttttacc ttcctcttcc
    34141 aattttgcaa gttttctgtt taaatctaac ataccaattc ctcctgttat aataatttta
    34201 ttttcaaatt aagaaatagt tattaaatct ccaatagtta tatctggatt tcctatttcc
    34261 acatgtattt ctcctggtaa atttacttca cattttccat caaatttgat tgtacaatgc
    34321 ccaatttctc taagagtctt ctgagcaata tcaccaactg aaactataca ataatctcta
    34381 ttccctatag taagtgtatc tcctatttca acatcacttt ttaacgttgc tattgaatga
    34441 attacagata tatcctttaa gtcgtcatca ttaatggttt catcatatat aataagacaa
    34501 ttgctttcat ccattaactc tttaactaaa ctgcctatcc cacttatctt aacttcatat
    34561 ttcatgacat tcctcctgat aatttatatt tatattgagt taattaaaag aaacatttat
    34621 tttttctttt ataaatttta tagcttgtac aatactctct tcatctttaa atttttgctc
    34681 tgcactatat atatctaatc cttctatttc ttcaatctct ttaaatttag ccattactgt
    34741 acgtcctttt aaaatttctc caaactttat aaacccatct gaatctgaag atataatggc
    34801 tatacttcct ttagaaaaat agcttttctt tttgcctgta gacactatat cacccttttt
    34861 tttagctcta tttaaagttt taaaatacaa tttattctgc ttcattataa atatagtatt
    34921 taaaatataa gcaacaaata aaatcactaa taatttcata tttatacacc ttccaaaaat
    34981 cacattattt ttaaatctgt ataacaacta taaatgctgt acaatagtta tataaggttt
    35041 ttaagtaaca cctttttaaa ttctaaaaaa gttctacatt tacttatctt attcgttaat
    35101 tttacatctt ggcctatctt taaaacttct tcataaattt ttactaataa gtctgagtct
    35161 atcttattct cacatggaaa cattgtcata agaattattt ttatacttct atttgcatat
    35221 tctattggtt cttctaaaat tccaactgcc attaaaaact tatctgattt ttcatttaca
    35281 gaatgaggaa ataataaacc tttatcaaat actgtgggag atttttcttc tctattgact
    35341 atattttttc taaacttatc atcaatgcat cccaaatcca taagatggtc catcattttt
    35401 tctaatgaag caagtatagt cttttcattt aatatcataa atttatcttc atctaacaaa
    35461 ttatttatta gtaaatttgt agaattagta gtgtcaatat tcccttctct taggcacaat
    35521 actgttttta attgttctct tagtttgttt tcatcaaata ttgtatttat ttttaatact
    35581 attgtattta tatttgatgt gtctaaatca atagttgtaa aaactatatc gtattcatct
    35641 aagttaatat ttctcaaatt aaaacttgaa agagtatcaa ttttaggatt atttcctatc
    35701 agtttttcta ctcttatttt caatagtttt gctgttccta gacctgtact acatataatt
    35761 gctatttttt ttattgaata gaatctactg ctatttcttt ctaaatatcc actgaaatgg
    35821 attgctatat atccaatctc atcttctgaa acttctaagt tatacttttt ctctattact
    35881 tttcctgcta tttgtgctaa tttaaatgga agtatataat tttgcttaat ctcttctaac
    35941 aaaacatttt ttaactttat attaaataat agcctgttta aagtaaaact aagatgatat
    36001 cctagaccta ctcttaattc atcctcattt ataaaaatac ccatatcgac atatatttga
    36061 ttaaatatat tttccatcaa ctcatcaatg tttttactaa ttctactact atttaaagca
    36121 cattctgatg ctggtgcatt tccactaact aacggtatag ttaaataaat aatttcttca
    36181 tcatttaaag tacattcaaa cattcctgat attatatgtt ttatttccct agcaataaag
    36241 tattcatcat atgatttaag taaatcaaac tttacatcat aatcttttac tttcttttct
    36301 tcttttactc tatagactaa aactactatg tagttaataa cttctcttaa catttcatct
    36361 gtaacataaa aattattttt tttaaataaa gtcaatagtt tttcttctaa atttatgatt
    36421 tcttcttttt tgattccttt aaaatacttt gaattactga aatctttcct tgagttttta
    36481 tacaactgat ttaatataaa cagtctaata tcaagttcat ttccatttaa tttcatacct
    36541 gtattctgtt ttttaatcaa gtttaaatta tatgaagcca aaactttttc tacatactgg
    36601 aaatcattta ctaaagtagt tcttcctaca cacatctcat cagctaaact atcaagtgta
    36661 ataaatccat ctagttctat caagtaattt agtataaact ctactctatc ttcttttgaa
    36721 tttaatgaaa atacattttt tctattcata tcaataatct tattgagtat ctgctcatct
    36781 tttatttcta gtttatagcc ttgacccttt atatatttga ttactgctat atcattacct
    36841 aaatctttat tcaattgttt tatatacgtc cttacacttc tagttgtgac attcaattca
    36901 tttgctattg agttaatact cacaaactct tttttactac acataatcaa tatcttaaat
    36961 atcttgcggt caatagaagg aattttctca gttacactca ttttgtatct cctccttgat
    37021 ttcattctag tacaaatttg aaaccaaatt aatacataaa atttcacttt aataaaggaa
    37081 aatttagtat taatctaact cgataattac agctaattaa tagtataaaa gctagtcttt
    37141 cattaacaaa aaatcttgac tagcttaaat ttatatttac aattttatta attaattcca
    37201 agccttatat tgacattaaa tattatctca atgcaaatac tgcaactcca tatgcaataa
    37261 taacagctat tggaccagtt attaaacgag agtaaaataa agctggaaca ccatactcta
    37321 cagtttctgg ttctgcttct cccaaactta atcctactgg tacaaaatca catccagctt
    37381 gcccatttat tgcaaataaa gctggaagtg ctaaatatgc tggtattgca ccaagaccaa
    37441 tttgtgtacc tacaagagtc cctactactt gagctataac tgcaccaggt cctagtattg
    37501 gtgataagaa tggaagtgtg caaattactg atataatcaa taatccacca atattacctg
    37561 caagtggaga tataactctt gcaatccagt ctcccagtcc agatgctaaa ataattccca
    37621 taagcatact tacaaatgcc ataaatggta ttacgttatt cattaccatt tggatagtat
    37681 ctcgacctgc atcataaaat tttgatacta cttgccctgc cccttgacca atagaaagta
    37741 ttatgttctt tttagcatat tcaccttgtg cttttgactt aacctcatca taattatcag
    37801 gctttctaat agaactctta ttttcgcttt tattttcttg agatttttgt ggcatatctt
    37861 ccccatctac aacacttata cagttaggat taacatctga tacataatat tcttctgtta
    37921 taaattttgc taaaggacct gtttttccaa ctggatttac atttattgta ggtatttttt
    37981 tctttggata aactccacat ctagcagttc caccacaatc aataataact actgctactt
    38041 cttcatcaga aactccagtt ttaaatccat ctacaatttc acaacccagt agttctttta
    38101 tttttaatgt tacttcatgg ataccaccag cagtcattga tagtatctta tttctattcc
    38161 cttctttttt tatatacaaa ggacctcccc agcctgaagt tcccttttct atttttaata
    38221 ttttattctc ctccatttta tctacctcct aagccttatt tgttgctcta ttttttcttg
    38281 ttagaaaagc atacattttt tctgttacta tacctcttat aaaaattaca attagaccaa
    38341 ctataaaata ccacaatgct agtgtagtag tttctttacc taaagtagtc aaacctgcag
    38401 atattcccaa ccatacaaaa agttctcctg catttgcatg tggaaaaaga cctgtaattg
    38461 gatgtacaaa tgaaactgct gcatcataaa atcctgcttt gtgctcttct tttaaaaatc
    38521 taccaaatgt atagcacata ggatttccca agaaaaatac tgatactaat ggaagtagaa
    38581 tatatcttgt aaaagagttc tttcctagct tagaagccca attattaact ctttcctcac
    38641 caattatctt aatcaaagag ttaatagcta ccattaatac aattagcgtt ggaagagtac
    38701 ctgaaacaag acctataaat tgttctcccc ctttctgaaa caaaccgata aaccactctg
    38761 cacctttact tagacctgta ataacgtttt ccataaaatt ataacctccc tataatatct
    38821 ttaaattttt aattttactg cttaccataa attttacaaa ttacatcttt tttctgtact
    38881 atatgctaat attgtaaatg tttttttatt aatatcattt taatataata tttttgataa
    38941 ataaatacat cttttttcaa ttttataaag gaaaaaattg tactaattag aattttcaga
    39001 aatatacaat tcttatttcg actatattct aaattcttct tagaaattta agaacttatt
    39061 tttatttctt ttattattaa aattatctaa atctgataaa aataaaaaat agatgctctt
    39121 ttacgaacat ctatttctta atcaaattat tttttagttt tcttatagat tattttatag
    39181 gtatataaat atcaatttgt gagttcacat tactaggacc taaaaatcgt tcatcatata
    39241 cttcaaaatc atctcttata tcaagttctt cttttgaact taaaaaccaa gtaccccata
    39301 tatattcata agttttgtct aaattatcta agctaccagt atgagtaaat atagcatact
    39361 ttccttcctt aatagttttt gaaacaaatg aatttggaat cacatcataa ctattaactt
    39421 caagtcctat tatctcatta aattccatac tttcactaac taggtgtatt tcagagattg
    39481 cttaacagat ttcaaaaact ctctttgatg gcaaagtatt tgggacaata tgatgtactt
    39541 ttctgaattt ctcccacaag tcaggtaatg aattattttc taaaattact ttatccttta
    39601 tacctattac ctttattttt tctatttctt ttataactgg tttaatcgtt atatttccaa
    39661 caagatgtct cataaaatct aactctaatt ttttcttttt accaacaaat acatcaattc
    39721 tattttttct atattctata gggctaacct tgtatataga tttaaatgct ctgctaaatg
    39781 cttctgaaga ttcaaatcca ctaccaatag ctatatctat cactttttta tcactatata
    39841 aaagttcttt tgtactactt actaatcgtc ttttttttat ataacttcct acactttcac
    39901 caaacataga cttaaataag cgtgttaaat gataataaga atatccagtt tcttttgcca
    39961 catcatttac agttatattt tcatgtaaat tattctcaat atacattaca gctttttcaa
    40021 aatactttaa gtaatccaat atggcacctc tcttctactt aaactcttta aatatgtaaa
    40081 atagcactat tttttactat actaaaatat tataactaat tcaatacgat aaataaaaac
    40141 ttttagttga tttatatgtc ctaattattt agaataattg aatacatttt ttattcaatg
    40201 aaatcaaaaa agtcagatgg tgctttttca atatttatgt ttatcctctg tgttatagat
    40261 ttaatgtcat tttttaaata gtagctctcc catttattct ctagtccacc ccataaaata
    40321 ttaaactttc ctatatttaa atccataact atacttttta aagttccaaa aaaatcatta
    40381 tagtaattac aagataagcc atttggatat tttgaagaca ataaattcat taactctttc
    40441 tctccaattt ttttagactt atttatatat tctttaatta atttatatct atgaatagaa
    40501 tttttcattg attgtggctc taatttatga agtttatcaa tatgtgtatg attagtagag
    40561 tgtaaaaaat attctctttt actttctaaa ctattgatta tatttacttc ttttttccca
    40621 tctaaagtct ccacaagtgc aatgtttcca gacttatctg caagcaataa attaatattg
    40681 tatgcaattg gcatatcctt taaatattct aatgcttcat ctacatcttt gcaattttct
    40741 aacaaatatc taataatagc ccaaaactgt aaacctacaa ttgctggttt tcttaaacca
    40801 tctgaattgc ctacaggaat accacatgat gactgactta cacctaagcc acattcattc
    40861 ataccttcac ctcttccaaa ttgcataacg gtagtaccta tatgtgcata ttttccattt
    40921 accttagttt tacataaaac aaaatcctcc atattgtgtg agaaatcgaa attacgtgca
    40981 aatagtacat gcccattttc agttaattct ggtgctaatg caacttgact acaacctggt
    41041 ttaagataag tcatagtata atataaaatt tgattacaat tcacttgaat tgcatcagca
    41101 aaaccttgca attcttcatt aagacctgga caatatttat caaacaactc tatcatctct
    41161 ttttcttctt ttttgcttac cacattagat ttattaatct gaccttctag tatctctggc
    41221 atattagcaa ccaattctcc tagtctgtat cctatctcat aatttgtacc actcaattca
    41281 atatttctta cttctaaagt ttccatatgt acccctccta tatatcttat aatcgatttt
    41341 atcactcgaa ttgtaatcat tcatgatatt ttgtgctaca agttaaaaaa ggttatataa
    41401 aaacagataa gcctcttttt cattgttaaa ataataaaaa tatatttaat ttcatacaaa
    41461 aaagagtgtc tcataaacta aaaagttcat tttgagacac tcttcttatt ttaaagagta
    41521 taattaaaaa tagtctaagt tctactcttc cttcattttt ttcaataact ctggattttc
    41581 aaataaatta aatcctgtta aagctaatat ttttatacca tcaattactc tatcttttgc
    41641 atatgaattt atagaagcct ccaaaaattc ttttgtatgt agttcttctc cattttcaga
    41701 aaacttcatc aaaggatgta tacatggcat tatttgactt aaatttccca tatctgttga
    41761 acctaacatt acttgttcat cttcatatat tccaaattcc tccataatct ttgtaaatat
    41821 gtctaccaaa actttatttt catttaatcc ttggcaagtt ggttcaaagt gataaaattc
    41881 aagttcacat ccagtggcta ttgcagcacc tctagcacaa tttttcactt tttctactac
    41941 ttcatcaaag taattttgtt cttttgccct tatctctaat cttacttttc ccatatcagg
    42001 tattacattt gcagcagttc ctgcttctag tataatacca tgtattctcg ttccatctac
    42061 taattgttgt cttagtgcat ttatattatt atatagtagt actactgcat ctaaagcatt
    42121 tattccgtta tatggcttag ctcctgcatg agatgctttt ccagtaaata tgaaatctag
    42181 acctcctatt gctataattt caggtgttac acaagttttt gaatttggat gtatcatcat
    42241 tgctgcatca tagccatcaa atacaccatg ttctatcaag taaggctttc catctccagt
    42301 ttcttcagca ggtgttccaa ttatacttac ttctcccttg taagtatcca gtatacttga
    42361 aagagctatt ccagctccaa ctcccataga tgcaattaaa tgatgtccac atgcatgtcc
    42421 attgcctgga agagcatcat attctgctat aaatgctatt ttaggaccat ctccattttt
    42481 cttggttgct ttaaaagctg tagccatacc tgccaagttt tcctcaacat caaaaccctc
    42541 ttctcttaga aattctgata tttttttagc agatttatat tcttgcaaag caatttctgg
    42601 ttcatcatat aaagattgac atagccctag aattttttct ttctttgaat cagccacttg
    42661 tattattctt tctttcatac caatcttacc tcccactaaa tttatttagt aatttttata
    42721 ttttattata actttaattt aactcatgct tatcctcttt taagtatcta ttttcccaaa
    42781 actcagcatt tcttatatct aactctatag gattaaaagt tctatcactc ctttttattc
    42841 ccatcttctt ctgtcttata taatcataat atgcctttat agctggtttt tttagtgtaa
    42901 agatggcaat taaatttata tatgttaata cacctataca tatatcacct aatgcccagc
    42961 ttgtaagtgg ttctataaaa caacacattg ctgcacatgc tataagcata aatctacaga
    43021 cattaattat gtacttttca tgtttttctg ctttaattct agttactaag taagatacat
    43081 tagtctccat catatatgag aaggctaata aagttgtaaa tgtaaataat aataaaacta
    43141 ttgctataaa aatatcacct aattgtggat gtaatgtatt tattgcactc tgtacatatt
    43201 gtggtcccgg ttctacacct ggtagtgctg tgcaaacacc tgtaacatta tacattcctg
    43261 ttattacaat cataatacct gtagccatac atattaataa tgtgtctaca taaacagaaa
    43321 atgcttgaac taatccttgt ttggctggat gacttacttc tgctgctgcc gcaccataag
    43381 tcccagaacc ttctcctgct tcatttgagt atatacctct ttttactccc caagatattg
    43441 ctgaacctag cattcctcca aaaactgaac caaatccaaa tgcagattta aacattgtta
    43501 caatagcctc tggaactaaa ctaatatttg ttataattat tactaatgtc ataataaggt
    43561 atgctccacc cattataggt actacttttt cagcaaataa accaatcctt ttaattcctc
    43621 caaaaattat tatcgctaat gcaatagaag atgctactgc tattgtcatt tttgaaaatc
    43681 caaatgcttg attcattgct agatataaag tgtttgattg tgtaccaggc ataaaaaatg
    43741 tataacttat tattgcaact attgaaaata aaactgaaca ctttttccac ccaagacctt
    43801 tttcaaaata atatggaggt cctcctctat actgcccttc atgctcatct ttatatattt
    43861 gagctaaagt agattctaca aatgcagttg ctgaacctaa tgtagccatt atacacatcc
    43921 atactaatgc tcctggacct cccattgcta ttgctacagc tacaccagct atatttccag
    43981 tccctattct tccagccata gatgtagcaa aaccttgaaa tgatgatata ccaacatgag
    44041 aactatctcc ttcaagcaag agagtaaaca tttcttttac atctcttatt tgaaaaaatt
    44101 ttaatttcaa tgaaaaatat aatcctatac acaaacacat tgcaactaat acgggtgacc
    44161 aaacaattcc attaatggtg ttaactaaat cggtcactta actcaccacc attcatttta
    44221 tatttataga caataattta aacagctata tttcaatatt ttatataatc tttatattaa
    44281 tatatctaaa aaatctacct tctatttatt tatattatct ttaatctaca atctacaaat
    44341 atttatttct aaaatcaaga gtattaatca tatctaaaca taaatttata aaatttttaa
    44401 cgacgtgtgt ttgaataata atcaaacaat ataaattgga atacatataa tgaaaagcct
    44461 gaaattatta ttatataaat agtacaatat atatttatta atatataatt aaatagtatc
    44521 tagttagatt ttaaattttc gtatttatta tgaggtttaa aattgagtac aactaccatc
    44581 tattttgaaa atctcttaga atttaaatta aataggttta tgtaggtaag aaaatagata
    44641 ataattgcca ctcaatttta caccttcagg ggtaacttta tgttaaaacc tagaaaactt
    44701 gataacattt tgatttttat actttattct ctaaacatta ttataaaact taatctattg
    44761 atatttttta tgttatttat acaatcacat tcatcaaaat aagtattgta tttatatata
    44821 cttaattacc aaattgaata tttaagcttc taatttactt gctcttctct ttttaacctt
    44881 taatatatat aaacaagata gtattccaat aactagaatt gctatttgga atataaatgt
    44941 atatgtgtaa cctttattgc cataagtatc tatccagtgt cctattaatg caaattggaa
    45001 tacatctggt gaaaatccta aagctgcagc tatacctata gtagttgctg aatatttaac
    45061 tggaactttt acttcatctt gtactgcata atatatacct tttcccatgt aacctaatat
    45121 acctactaca aatgttaaag ctatgaatat agtcattgga gttgatgcag gtaatactag
    45181 gaataaaact attactgcta taccaaatac atatattggt aaaagtactt ttgtaggaga
    45241 ttttaatttg tctgcacaat atcctccaaa tggtgctcca aataatttta gaccatgctg
    45301 tcttattatt gctaatgcac cagataatgc tacagaacct ccaagtacag atgttatata
    45361 tggtgtaaaa taagacattg taactgtgaa tgaatataca cagaatatac ttattcctac
    45421 tagccaagta tttggtgatt ttagtactgt tataaaatca ccagcagaca ttttttcacc
    45481 tgcttcttct ctttcttctt taatatctac atctttaatt acaaaccata atactggaca
    45541 cattgctatt gataatattc ctaaagatat cattacccat ctcataccca atgtaggagt
    45601 tgcaaagcat gtataaatat ataagaatat tgctcccatt actactccag aaactccaac
    45661 catagcttca ttaaatccat aaaccttacc ttgattatct tttcctataa ctctaagtat
    45721 ttttaccata gaaggatagt tcataactaa tgatgtgatt gcacaaccta cccaagtagc
    45781 aactgcaaat ggatagttca tattaaatgc aaataaaaat gatactactc cattaagaaa
    45841 tacagaacct aaaattatct ttctataatc aaatctatct gctaaccagc ctcctatagg
    45901 agctccaaat atattaccta acccataaat tgtaagtaga aaacctagtt gagtgtttgt
    45961 acattctaat gcttttagga ttggatcata taatgtatat tggataaatg gtataatata
    46021 aactaattcc caagatattg ctataataac aagttgaaac attaactttc caaactttat
    46081 accgttttct ttttctccca tatttaaacc ctcacttttt atatttattc acaagcataa
    46141 ttgagttctt tttttataac ttctgcaagt atctcaacac ctttaacgat ttgttcttct
    46201 gacattgttg tatagttaag tctcatagta ttttttggac cattatttgc aaagaaggac
    46261 tctccagaaa cataagcaac tccagcatca atggctttat ctaataaatc atctacattt
    46321 atactttcag gaagttcaac ccatataaac attcctccat ctggttctgt atatttagct
    46381 tcctctggga aatgtttctt catagcatct aacattagca gacatctttt cttatactct
    46441 gctcttattt tttctatatg ttcatttaag ttgtatttct ttaaaaattc tattacttgt
    46501 acttgcgaaa attgatttga ctgtaaatct ataccttgtt ttaaaagttc tgccttatct
    46561 atgatgtcta cattaccaca catccaagca actctaaatc ctggacataa tacctttgaa
    46621 aatgacccaa ggtacaatac tttatcttta gtatcaagag atttaagtgt aggtagaggt
    46681 tctggtgtaa atcttatttc tccataagga ttatcctcta ttactatgac atcatattta
    46741 ttcacgactt ccataaaatc ttttcttctt tgtaaagacc atgtttttcc tgtagggttt
    46801 tgaaatgttg gtattacata tatcaccttt atgttagaat tttcagataa taatttgtct
    46861 aaatcatctg ttaccattcc ttcttcatct gtatctactc ctaaaaaatc acattcataa
    46921 ggtctaaatg catttattgc acctaagtaa cttggatttt ctgtaactac tacatctccc
    46981 ttttctaata aaatcatagc acttaatgct atcccttgtt gtgacccagt agttattata
    47041 atattttctg cttttgtatc aatattttct tcttctttca ttctttttac taatagatct
    47101 aacaactcat cttcaccttt agtaggtcca tatgctaggg caaattttcc cctttcatta
    47161 agtacttttt gagttatttc acttatctct tctattggaa ataaatttgg gtcaggaagc
    47221 cctgcagcaa aagatataac agttccacca cttgctacct tctgagctat tttcttttga
    47281 gaatctctta tagctgaagc ttttaccata tccattcttt ttgcatattt cataatattt
    47341 tttcctcctt aataataatt tcttattgtg atgctaggca cgctaatgct attgaattta
    47401 tttttatttc agctgtgtca gaacgtgaac ctaaaattat cggatttgtt gctcctaaaa
    47461 ctatacctgc ccacttagct ttattaaatc taagccatga ctttcctaat atattccctg
    47521 cttctatatt tggaaatact aataaatcaa catcaccagc aatattactt ttaatgcctt
    47581 tatgttctgc tgcatgtgca tcaaatgcta catcaaatgc tattggacct tccactatac
    47641 actttggtat ttctcccgat ttttccatct ctacaagtag gttggcatcc actgtagatt
    47701 gtatcttagg gtctaccatt tcatttgcag taagtatcgc agttttagga ttttccatgc
    47761 ctatactttt catagtaaga agtgcatttg tcattatatc ttttttttga tttaagtttg
    47821 gcgatacatt tattccacta tcagtacaat aaagaagttt atgatattga ggtaattcat
    47881 atactgcaag caaacttaat aatcttcctg ttctaagacc cgtttcttta tttaatatag
    47941 ctctcatata gacacttgta tttactaatc ccttcataag aactttagct tccttatttt
    48001 taactatctc tacagctttt ttaactgatt catcgggatt ttgacaacct attatttcat
    48061 gaccttttaa tccaatttct cttgatatac tttctatttt atccttgtct cctacaagaa
    48121 ttggctttat aatgtttaaa tctgttgctg atttcacagc ctttaatact tctttgtctt
    48181 ctgcaacagc aacacttaca ataacaggtt caagcttttt agcctcttct aataaattat
    48241 taaaatcttt taacatactc tttctcctaa atattaataa gtttttgcta tttcttctcc
    48301 attaagtact ctaagtgccc ctagagcaag tgcctccatt tccatctctc ctggtactat
    48361 ctctattgga gctagatatg aaactttttc tgctactcct ttgactacca tttctgagtg
    48421 agatatccct cctgtcaaga taactctatc tacattccct gaaagtgaag ctccatacat
    48481 agaaatttct tttgctactt gataaataaa tgcatccatt ataagttttg ccttttcatc
    48541 accctccttg attctgtttt caatttctat catgtccttt gttcctaaat aatcgtacat
    48601 tcccccaatc gaacttactt ttgcgaccat ttcatcatga gtatattttc cggagtaaca
    48661 caattctata agaggatatg caagtaatcc accactcctt tctggagaaa atggaccatc
    48721 agacctacca ccacttccat caatcatttt gccttgttta tgtgctacaa tcgatattcc
    48781 tgaacctaaa tgagctacaa taaagttata atcctcgtat tttcccccta gtttttgtgc
    48841 aatttttctt gaaacagctt tatggtttaa tgcatgtaac caacttgctt tttctatgtc
    48901 tgatattcct gtaatcctcg atacatcatc aaattcatct acagaaactg ggtctactac
    48961 aaatgattgt actcctattt catcagctat agttttagct aataatgcac ctaaatttga
    49021 tgcatgttcc ccatttattt catttctcat atcctcaatc atttcttcac tcacagtata
    49081 ggtaccacct tttatagcct tcataagtcc accacgacca actactgcgt caaaagaatt
    49141 tatactatga ttctcactac ttaaaatatc tactatcagt tgttttctat aatcatattc
    49201 atcaaatact ttagaaaaat tttttaaatc ttctcttgta tgggttatat tttttttcaa
    49261 aatttcattt tcatcttgga aaacagaaat ttttgtggat gtaccaccag gatttattac
    49321 taaaactttc aatttaacac cccctagttc tactatacag aacgccgttc ttgtattccg
    49381 acctaaaaac ttcgtcctat tgtccagaac gacgttctat attttattaa ttaaatacta
    49441 acatataaaa ataagtattt caataattat tttaaatatt taaaatattc attcgtagtc
    49501 gtatccagct tcaaatgctt ctacattttt agaattgaat ttacctttgc cttgattttc
    49561 aaagtattca cacataccac tttcaaattc ttcttttgta aataaatcca aactctttac
    49621 catagcacct aacatgcaaa tgttagcagc tttttcattg cctaaatttt gtgctatttc
    49681 agtaacaggt acttttataa cattaatgtc ttctctgtac tttctatcct tacttactag
    49741 tgattcattg acaaacatat aaccattttt tttcattaaa ctttcatact tatctactga
    49801 tacgctgttc attcccaata gtatatctgg attttttaca caaggatttg caattttttc
    49861 atcacttaca acaacattgc aatttgcact tcctcccctc atctcatttc cataagatgg
    49921 gaaccatgta attttctttt ctgccttata tgcaacatac attataattt ttcctgctgt
    49981 aagaactccc tgtcctccaa aaccagcaca tataatttca ttcaacatat tatttcctcc
    50041 ctaatcaata aattctccaa gtggatactt tggaacaagt tcattttcaa ttctcttcat
    50101 agcatctact ggctttaatc cccagtttgt tggacatggt acaagcactt ctattaagca
    50161 aaaacctttc ttttcttttt gtttttctag agcttttttg atgtatcttt ttgttgtatt
    50221 tatttcttta gggttagtta ttgttcctct tgctagatat gctatatcta aatttcccat
    50281 aacttttaca acatcaaatg ttgaaccatg atctgcgtaa tttctacccg ctggagtaga
    50341 agctgtatat tgaccttcta tagtagttgg agccatttgc cctcctgtca ttgcaaacat
    50401 attattgttc ataacaagaa atattacatt atcatttcta gtagcagctg acatagtttc
    50461 tccaagccct attgcataag ctccaccatc tccagctatt gtaaatatat atttatctgg
    50521 tctaactctt ttcatagctg ccattgctgc tcccatttta ccatgaggtg gaacgacaac
    50581 atctacattc atactaaatt gaaacatatg attacaacct atatctgaac atataattgt
    50641 atcttgacat atatccattt ctgttaatac ttctccaata attctatcga ctatagagtg
    50701 tccacagcct ccacagaaca tattttcaca catcattatt gctggtgctt ttttagccat
    50761 aattaaaata cctcctcttg cttagctttt ccatctataa tctgttgagc aaaatctatt
    50821 aattgattta cttctgccat atattgagct gttgctactg aatatactgg aaatctatta
    50881 tcacatgcta taattacatc ttccttcatc tgtgccatca tgttcatttc aactgttaca
    50941 agtcccttca atgaatcact taatttctta aatgcttttc ttgggtaagg ccacaatgtt
    51001 tttggtctta ttagacctaa tttcattcct tttgctctag catctctaac tgcaccttct
    51061 gctattcttg atgaaatacc gtatgccaca aataccactt cagcatcttc tatttctatc
    51121 tcttcccatc tttgttcatc ttcttgaact tttctcattt tttctatata ccctttttgc
    51181 catgtatctt ggtcttcaaa atatgttata tcagttatta ctttattttt ttctcctaca
    51241 ggtgttcctt ttgcagccca tggagcttta tccatatcgt attctttcat tggtggtgct
    51301 atacaaggtt ctaccatttg acctattgta gcatcagaaa gtataagtac tggatgcata
    51361 tatttttcag ccaattcaaa agattcatat gccatatcca tattttcttg aacactatta
    51421 ggtgctaaca cgattaaatg ataatctcca tttccaccgc cttttactgc ttgccaataa
    51481 ttatcttgac cagctcctat aaatccatca cctataccat atctttgcac acatgctaca
    51541 actgctggca aaccagctga tacccaatat gcaatacctt cttgttttaa tgaaaatcct
    51601 ggaccagatg aagaagtcat agctcttgct ccaagtgcac ttgctcccat aaccatattt
    51661 acactggcta tttctgattc accttggata aatactcctc caacttcttt ttgtctccat
    51721 gccatcattt ctaatatttc tgattgtggc gttattggat aacctgcata aaatctgcaa
    51781 ccaccacgta tagcaccttc tgctaaagct tcatttcctt taattaataa actttgcata
    51841 ccttttctcc cctctaataa aaataattta taatatctca aatactaaat cagggcacat
    51901 tgtataacaa gcgccacatt gaatacattt ttcttcatcg actttaatag ttacaaagcc
    51961 ttttttattt gtgtagtcag aaagacttat tgcatctttt ttgcaagctt caatacaaag
    52021 atagcatccc ttacatcttt caacactcaa cttgactttt tccatttctc aaatctcccc
    52081 tttatgtaat atttttactt aattttaaat atataatatt tatattttgt ataaatacta
    52141 tatatgcatc aattttgttc tatagtatag aaccttgttc tatttttatt gcttaattaa
    52201 aagataacac attcgcttat atatttcaat aacattttaa attttaagaa tatttaattt
    52261 tagattaaag aaaaataggc tacatttaaa ctgatattta caaataacaa tttaaatata
    52321 gcctattttt attatcgaga ttaaaaatca tctaaaaagt tcagatatac tttttgcagt
    52381 ttctataact cttttaatct tatactcaaa gtccccttct ctcattctta tagttggacc
    52441 tgacaaactt atggctgcaa tagctttatt atttttatct aagataggtg ctccaataca
    52501 agttagtcca tgttctagtt cttcatcatc tatagcatat ccttgttctt ttatttttgc
    52561 taaaaaaagc atcatatcat cccaattatc aattgtatgt tctgtatact tgtgtattgg
    52621 tgtttttcta tatttttcaa aatctataga atcattaaat gccataagac atttaccaac
    52681 tgctgaacaa taacattcac tacttgaacc aacggatgga tttactgaaa gtaattgatt
    52741 tgaaccatac tctttatgta ttatgatact tcttggagaa tcttgagctc tttcttctaa
    52801 tatagataca ttaactactt cgttaaattc ttgatttaat tttttcgtat atggttttac
    52861 tatttcagtc aatgacattt tttctcccac aaccatacct attgcatata aatttattcc
    52921 tagccaatac ttaccattct ctgcattttg tataacaaaa cctttgtttt caagagtaac
    52981 caaagttcta tgtacagtac ttttatatac tcccatagcc ttacttattt cagttattcc
    53041 catttctctc ttttcatgat ataacagcaa aattatgtct agggctctat ctaatgcatt
    53101 tattatttct cccatataca aaaactcctc ctgcaaatat taagtgctac tcccacactc
    53161 tactaaatat tatatattaa aattacaaaa ttatctattt atcttaatta tattttataa
    53221 aacaaaaata ttatacttaa tttgtaaaat aaaaacaaaa tactcactat gtccttatta
    53281 ttcttacttt taatagaatt attctgttat atttttatcc tgactagata ataatatata
    53341 tatctattat acaatagata tatttttata caagactaac aatgaggtga aataatggat
    53401 aattttaaaa agatattgtt aaatgaacta cctaatttta aagaatattc ttcaaaattt
    53461 ttaaatggag aaataaataa aatgcaatat aagggatttt ctggtggata tggtgtttat
    53521 gctcaaagag acaaaaaatc ttttatgata agacttagag tatctgctgg agttttatct
    53581 cagtatcaac ttaataaaat ctatgaaata gctattaaac acaacttaga taagatacac
    53641 ttaacaacta gacaagctat acaattacac gatttatcta taaattcaat tgttgatatc
    53701 atggaagaag gaataaaaaa tgatatattc actagaggtg gtggtggtaa ttatcctaga
    53761 aatgtcggat tatctccatt atctggagtt gaccctagtg aagtctttga tgttactcca
    53821 tatgcagttg ctactgataa atattttatc aaaaatgcta ctacatacca tttacctaga
    53881 aaattaaaag tttcttattc taattgttac acagatactg ctcattgtag tatacaagac
    53941 ttaggatttg ttgctacttt gaaaaatgat gaaccatatt tcagagtttt cttaggtgga
    54001 ggtctaggta aacaacccaa agttgcttta gaacttgatg aacttataaa gccgaaagac
    54061 gccttatatt gtgttgaagg tatgattaaa ttctttatgg attatggaaa ttatgaaaat
    54121 aaaaacagag ctagggttag atatatggtc gaatcacttg gtgaagaact attcttagaa
    54181 aaatttaaag aatactataa attagaaaaa gaaaatggta gtcttgaact caatattgaa
    54241 gaaatagatt actctaaacc tggagttaaa atagatatac aagattctag actaatacct
    54301 caaaaacagg atggtttata cactgtatat atacatccag ttggaggtat tttgttaaca
    54361 aaggatttaa gtactttact taaagaatta gataatgttg aaaatcctat gattagacta
    54421 ggaatgacag agggattata tattttaaat ttaaatggaa atgaagcaaa aagaatatta
    54481 gaaataagta aaactattag ttgtaattct caattagaac aaagtatatc ttgcataggt
    54541 gttccaattt gtcaaatggg catacaaaat agtcagaaaa tgttacatga aatcatagat
    54601 tattttagat tacaaaataa tgaagaaatt ttaaataaag cacctaagtt atatatatca
    54661 ggatgtttaa attcatgtgg tgttcatcaa gttggtagca taggtttatg tggtaaaaag
    54721 aagaatgttg atggtatatc tacagatgca tttgaattat ttgttggagg cagttttgaa
    54781 ataggtaaga ctagattggg aaaatcactt ggagatttta aagctagtga tattcctgaa
    54841 atgctttata aaatatcgga cgcatcttca ggcaattttt atgaatgggt aaattcaaat
    54901 gataatattt taaacaaaat aactgataag tataaaatat aatttattat atttacttac
    54961 aaaaaacatg ggtgtctcaa aatgaacttt ttagtttatg agacactctt tttctatgaa
    55021 atcaaatata ttttcatcat ctcaacaatg aaaaataaga ctatctctat tttgagacag
    55081 ccttatttct tataaatagt ttaaatttta tttataaaca attttagata aatcacaaat
    55141 tcctagcata gtatcatata cttgtttaag taaagcaagt ctattgttct taatagcttc
    55201 atcattatcc atgaccataa ctgtatcaaa taaattatca actactggtc ttaaagatgc
    55261 aaattcatct aaagcaatac catatttctt atcctttaat aattcattaa cttttacctt
    55321 tacttgttta aattcattgt aaagtttaat ttcagcatct tcttttaata aagattcatc
    55381 aattttatca ctttctgctt tttgagctag agtagaaact ctattaaatg cagtaagcat
    55441 ctccactaat tcatcttttt ctagccaatt attaagctct aaagctctca tatgcatatc
    55501 agaaacatca tttatatcag aacttaaaac agcatcaaca acatcatatc ttattcctaa
    55561 atctttaaat agatttttta ctctctcatt gaagaaattc attatttgct caacaacttc
    55621 ttctttatta aaatctaatt cagaataatt gtctaaagca tgttcaataa gtatttttat
    55681 atccacagca acttttctgt ccataagtat actaagtata cctaaagctt gtcttcttaa
    55741 agcatatggg tcttgagaac ctgttggttg tattcctata gcaaagaaac ctgctattga
    55801 atccaactta tcagctattg ataaggcaac ccctgcatta gtcttaggaa gtatatctcc
    55861 tgcaaatctt ggaagataat gttcaaaaat agcttcactt acaacatcat tttctcctcc
    55921 aacttttgcg tattcttttc ccataaaacc ttgtaattca tcaaattctc ctaccattcc
    55981 agtaactaaa tctgccttag ataatttagc agcccttata gtatctgcct tttcatctac
    56041 taaacctaaa ctatcaagta tatcagcact taatttttca agtcttaaag ttttgtcgta
    56101 aatagttcct aattttactt ggaatacaac agtttttaat ttttctatgt agctttctaa
    56161 gtttctctta gtatcttctc tatagaaaaa taaagcatct gcaagtcttg cttctaaaac
    56221 tttttcattt ccagctttaa cattgtctat tctgtaagaa tcaccatttc taacagctat
    56281 aaagttaggt aacagttttc cttctttaag tactggaaaa tatctttgat gttgtttcat
    56341 aggagttata acaacttctt ttggtagttt tatataatcc acatcaaatt ctccataaaa
    56401 agcagttgga tattcaacta aataagttac ctcttcaagt aaatcttcat caaattcaac
    56461 ttctccacct aaagaatttg ctacttctat acattgtttt cttatcattt cttttctctt
    56521 gttttggtct aaaactatat aatttttttc taatttttca aaataatctt ctatagaatc
    56581 aacttctatt gtactttcac ctaaaaatct atgacctttt gttacattag aagatattat
    56641 tccttctaaa tcaaactcta atactttatc atttaacaat gcaactatcc atcttatagg
    56701 tcttgcaaat ttaagatttt ttcctcccca acgcatagct tttgggaata ctacagattt
    56761 tatagtctct ggtaatatgt cttttagtac ttctgaagtt tcttttccat cttgctttat
    56821 agtcgcaaat atatattctt cttttccaac ttgtttaaaa tatatgtcag attcgcttaa
    56881 tcctttgctt tttataaatc ctaatgctgg ttttgttaaa ttattttctg catcaacagc
    56941 aattttttta gcaggaccct ttatttcctc ttctaaatca ctttgtctat cactcaatcc
    57001 ttcgactact aaagtaagtc ttcttggtgt cccataagca tttattttat caaaagctat
    57061 tctattttca tcaaataatt tactaagatt gttttttaat tgttctagtg tactgcctac
    57121 aaatcttgat ggcatttctt caacaccgat ttcaaataaa agataatttt tcattatttg
    57181 tcaccgtcct ttaaaagagg gaatcccatt tcttctcttt gttttacaaa agtttctgca
    57241 acagtctttg ccatatttct aactctacct ataaatgaag ctctttgact aactcctatt
    57301 gcacctcttg catccaatgt attaaatgca tgagagcatt ttaacacata gtcatatgac
    57361 ggtattacaa ggccattttc cataagtctt aatgcttctt tttcatatat atcaaacaga
    57421 ttaaacaaca tatctgcatc acataattca aatgcgtaca ttgagttttc atactcagct
    57481 ttattaaata cttcaccata agttatttta tcattccatt ttaaatcata aacactatca
    57541 acttcttgaa tgtacatagc taatctttct aatccatatg taatttctcc tgtctcaagc
    57601 tcacattcaa tattacctac ttgttgaaaa tacgtaaatt gagttatttc cataccatct
    57661 agccaaactt cccatccaag tccccaagca ccaactgtag cagcttccca gttatcttca
    57721 acaaatctta tgtcatgctc acttgggtca attccaatct ctttcaaact ttccaaatat
    57781 aattcttgta tattatctgg agaaggtttt agtataactt ggaattgatg atgttgatat
    57841 agtctgtttg ggttttcacc atatcttcca tctgctggtc ttcttgaagg ctctacatag
    57901 catacttgcc aaggctcagg tcctaatgat cttaaaaaag tattaggatt catagttccc
    57961 gcaccttttt caatatcata aggttgcatc atgatacaac cttgctttga ccagtatttt
    58021 tgcaacgcca gtatcatctc ttgaaaattc ataaaaatcc ctcctataac aataaagcct
    58081 ctcgtctaca cgaaaggcta ttttaatagt tcttctacaa cttttagaat atcaaattct
    58141 ataaaatttg tcaatgttag tgataattct tataattatc ttctcttcat tttttaaaag
    58201 tcactttata tctatttatt ttcgtcttcg tcttctttat tcttttcaga ttcttctttc
    58261 ataaggtcag cagttacatc tttgtcatct tcttttttgt caactactac atccttcaca
    58321 tcttttgctg cattagttat catattcttc aaaacgtgaa gtttttcttc attcaattca
    58381 cctaaatcta caatttctcc atcttcttca ttttgaactt ttatacgata tttacttata
    58441 acagcagctg ataatccaac taaagtagct aatggtacaa aagctaatcc aacaactcca
    58501 actgttaaag gaatgttcat catagttttt ccatcttttt caactattat tctcactaca
    58561 ctactttttc taagaagctc ttttaattga aactttatat tttctccatc tttgccaaat
    58621 acttcttcca tagtttcttt agcagatttt gctttacaat tacaagtatt ttttttattt
    58681 tctaaatata ttactgcctc aattacatct ccattgcaca ttactaatgc ttcttttgct
    58741 tctgcataag ttgctcctgg aactctttca aagactgaat caaccatttc aatagttata
    58801 ttactactca tcattatcca ctcccttatt attttttaca ctttgcaata cgtgtaatga
    58861 tttaaaatta atattatcaa cataaacttt caaatacttg tctagaatat tctcaagttc
    58921 atgtgttata tattttgata ctttagcttt actacatgtt aaaatatcat ttcttaatac
    58981 atattccata agacttatag ttgttaagtc taattttata ttattatcaa aaagtttact
    59041 acacttacta catagtatac caccttcgta gatattaaac acagaatttt gtaaaatttt
    59101 acattcacaa ttaatgcatt tatttactat aggtttaaat cctatatagt ctaaaaattt
    59161 taactcgaat gctgctgtta taaacctatt gtctgtatta tcctgtgtat acaaatacag
    59221 agtctgcgca agtaatataa atagcctatt attagtctga ttttcaagta tagaattttc
    59281 aactaatttt gtaatatatg tagcataaga aaatgcctct atatcatagg atatattata
    59341 aaaacttttt attatttcac tttgagtaac cttgtacata ttaccttgtt tttttaaggt
    59401 aaaattgcta taagaaaata actgtgatga tgaaagcaaa gagctcttat tttttttagc
    59461 tccttttgct attgcagata cttttccaag ctttcttgta aatagtgtaa gtattatgtc
    59521 actttcctta taccttatag ctttaagtac tatcccctgg gtgttcagga ttatcatcgt
    59581 cttctttttt ctcccttact tcttcaattt cttcatgtat gtttttgcaa tcacagaaat
    59641 ataaatatgc atctatacta cctgtttttt taaaaacttc ccaactgata ttgttcattt
    59701 ttaaaaaacc cccttcttac atttatactt atatttttag taagaagagg ataaatcata
    59761 cataaagtta ttaaacaatt tttgacaata atgccgttgt tattataaag taaactgcta
    59821 taccagttat atcaagagct gtagatataa ttggtgatga aactgtagat gggtctgcat
    59881 ccattttttt taataaaaca ggcataaacg cacctattgt tgcacctaaa accatattta
    59941 taaataatga tattgaaaca attaatacaa tgtctaactt tctcataaca aagtaaatta
    60001 caatacctgt tattatacta cacaaaagac ctgtaataat acctacaata ccttctctaa
    60061 ccacattgct aaaatttaaa tccttattag ataatgttat tactgtaaca gatgatgatt
    60121 gagttccaat atttccaccc ataccaatta ctacaggtat aaaaaatact aatggagcat
    60181 atacaggatt cattatatag tctaagttag aaagtattaa tgaagccaac aaccctccaa
    60241 ctaaggtaat aattaaccaa ggtaatcgtc ctctaagtgc tgatattatt tgctctctca
    60301 atgtagggtt ttctttttca gcaacttctc tttcatgttc tgaacttcct gcaaatttat
    60361 acatatcttc agttgcttct tcttccatta catcaattat atcatctact gttattattc
    60421 cttttaattt ttcttgtctg tctactactg gaattgctat taaattgtat ttagatacta
    60481 atcttactgc ttcttctcta tcttcatcta cataaacaga gattatattt tcactcatca
    60541 aatcttctac tatatttgcg tctctagcta ttattaattc tcttaatgac aatactccaa
    60601 ctagtttttc ttcatcatca accacatata tataataaat agtttcagct tcttcagctt
    60661 cttctctcat atggtctata gcctcaagag ctgtcatatc tttatttata gaaatatatc
    60721 cagtggtcat tgttccacca gcagaatctt catcatagaa tagtaactct tttacataat
    60781 cggcattctc ttgattcaaa agatttatta tgtgttctct ttcttcttct tcaagttcac
    60841 tcaacttgtc tgccatatct ccaagagaca taagttcaag tatatttttc gagtgttcta
    60901 catccagttt agataaaata ctaataaaaa actctacact accttcttct aatatagaag
    60961 atgccatatc taaaggaagt acttcaaata attgaatttt catgtcttcc tctaaatttt
    61021 ccattatatc gaatatatca attatatgat attcctctat taattctctt aactccaata
    61081 ctttattatt atcaattaat gattttactt catataataa atcttgggaa gcatccagtt
    61141 tcctatccat ataacccacc tttatttatc attatatcca aaattattta tataattttg
    61201 taaatttctc caattttctt tgactttaac ccataattga agatttattt gtgaacctaa
    61261 aagcaattct atatcttgtc ttgctgactt acctattcct tttagtttcc taccattttt
    61321 tcctattatt attcccttat gtgaatctct ttcacagtat attacagcag atacatctac
    61381 tatttcctta tcatttctcg ctttcatttt ttcaatttca acagctacac catgaggtat
    61441 ttcatcatta agatagtgaa gaactttttc tcttataagt tctgctatta atactctttc
    61501 tggctggtct gtaatcatat aatctggaaa atactttggc ccttcttcta aataattttg
    61561 tataactttt attaaggtat ccgtattctt tccttttaat gctgatattg gtactatttc
    61621 tttaaaaatg ccttctctat catacatttt gattatatca aatagctcat ctttttggtc
    61681 tagttggtct attttgttta caactaaaat tattggtgtc ttaacacttc ttaaatcctc
    61741 tattatcttt ctatctccag gacctatttt tttagaatca tcaactacaa ataatattaa
    61801 atctacattt ttaaaagctt ctgttgctgc ctttaccata aattcaccta atttattttt
    61861 tggtttgtga atacctggtg tatctaagaa tactatctgc atttcttcat ctgtatatac
    61921 tgcttgtatt gtatttcttg tagtttgagg cttatcactc attatagcta ttttttctcc
    61981 aactacatta ttcattaaag tagattttcc tacatttggt ctacccacta tactgacaaa
    62041 acctgatttg aacattaact gtctcctaac tttttatctt cttgttttaa ttacttaaat
    62101 ttatttatac ttttaaattt attttaaatc atttccagag aaatagtttg gcaacaaatc
    62161 ctttatacta tgctcaaaca cctctccttt agtatatccc gttattattt ttatatcaga
    62221 accaaactct ataattacct gcctgcatat tccacatgga tatgtttgct cattattttc
    62281 tgagttatca cttgctatag ctattttata gatatcctta tcaccctctg atattgcttt
    62341 aaaaatagct gttctttctg cacaatttgt tccacctaat gatgcacatt ctatattaca
    62401 tccagtataa actttaccac tcttagttaa aagagctgca cctactctaa aacctgagta
    62461 aggagcataa gaatgttgtc tggcatcttc tgccaacctt aacaattcta tgttatccac
    62521 aacaactcct cctgtataca ataattaaaa gttattttta tttaatactc tacattatat
    62581 cataaaaatt taattagcac agatttgttt tattttaaat attttatgta catttatttt
    62641 aattatagaa cattccaagc tgaaatacta atatagctat caacacacct aacaaagctc
    62701 cagcaatagt ctcccaaaag gtatgtattt ttccttcaat tctactttgg gcaactaata
    62761 cagccattat atatgcaaga gtagaggcaa ctactctttc agtcataagt gtaattgcag
    62821 ttgctatagc aaatgctaag gcagcatgac cacttggcat tcctcctttt agaggagtac
    62881 ctgtagaagt caatgctttt acaactacaa cagctataag aaccaataat atacatatca
    62941 aggttatatg taattctgat tctcttattt tataaattaa tattccagat atatctgtca
    63001 acttatcata aaacaaaata tatccaacta ctactgaatt tagtgctgcc actagaacgc
    63061 ctccagctgc aacatctttt gctatcttag caagaacatg atattcatca gttactaaat
    63121 caacagcttt ttctatagct gtattaaaca tttcagcaac tacaactaaa catatggaca
    63181 taagtaacat tatcatttct aattttgaaa agttaaaaaa caaacttatt ataagaacag
    63241 caactgaacc taaataatgt attttcatat ttctttcaaa tttaaatgta tacaatatcc
    63301 cttctatagc tgcattaaat gctttaatta taccttgacg agttttttct ggtttcataa
    63361 aaactactcc cttgttatgt ttaacttatt taatatgtgt tcttcttttt ctctcatttc
    63421 ttttgtattt tcatctgtat cgtggtcata acctaaaaga tgaaacatac tatgacatat
    63481 taaaaaacat acttctcttt caaaactatg gttatactct atactctgtt ctaaggctct
    63541 ttcaagagat actactatgt cacctaggga ttcttcttct aactcaacat cctcaaaatc
    63601 atcacttaaa agaggaaatg ataaaacatc agtcactcta tcaactcctc tatattctct
    63661 atttaattca tgaatctctt tattatctac aaaagaaaga ctcacttcat aattatcatc
    63721 atatccttca taatctaaac attctatgat tatatccttt atcttttcaa ttaactcctc
    63781 acttacttct aatttatctt gtctatcatc tagtatcaaa tccattcact acacctactt
    63841 tttattcatt aataatgcta tatatctata ttactacact tttactttct tttgaaagtc
    63901 ttttcctgca ttttcgcttt tttacgttct tcttttttaa attcttctct tttgtcgtgc
    63961 ttctcataag ctcttattat tctctgtacc aactcatgtc ttacaacatc tctatctgtt
    64021 agcattatag acccaatacc tggaacacct ttaagaatct ctgtagcttg tattagacca
    64081 ctcttcttat tttgtggtaa atctgtttga gttacatctc ctgtaactac agctttagag
    64141 ccaaatccaa gtctagttaa aaacattttc atttgttcag aagtagtatt ttgagcttca
    64201 tccaatatta taaatgaatt atcaagtgtt ctacctctca taaatgcaag tggtgcaacc
    64261 tcaatagtac ctctttctaa atacttatta aatttatcag cacccaacat ttcaaataag
    64321 gcatcatata gtggtcttaa atatgggtca actttgtcct ttaaatctcc tggtaaaaaa
    64381 cctagactct ctcctgcttc cacagctggt cttgtaagta taattctact aacttcatct
    64441 cttttaaaag cttttactgc catagcaacc gcaagataag tctttcctgt tccagcaggt
    64501 ccaacaccaa aagttatatc attattttct ataagtttta tatattcttt ttgacctaaa
    64561 gttttaggtt gaacagcttt tcccctttga gttatgacga ttgtcccctc aagttctttt
    64621 attttttgtt cacttccttc aagcaaaaga gataatgaat aagaaatact ctgcttatct
    64681 aaatgcttac catttgatac agtttggtgt aattcattca taagttttaa tgcagaatct
    64741 acattttttt cttctccaat taaaattata ttgccttctc taagtattac atctatattt
    64801 aaagtcttct ctattaattt tacattttca tcaaagttgc caaataactc tctttcaaag
    64861 ttaccatctg ctattgtaaa tttcttttgt attatcaatt gaattagtcc tcctaagatt
    64921 ttaagtttaa ttttattagt tgttattgct attattattt tgactattat tactattttg
    64981 attactatta ttttcatcag aattgttttg gtctttatta tccttattat cctcatcaaa
    65041 ctcatttctt atatcattta atggtctttt ttctggattg gaaggaactt cctcttcacc
    65101 ttcatctggt ttactttctt cctttataaa cctttctgct tctgacttac taagaggata
    65161 aattttagca atattttcac tagtttgaac tgttattaaa tattctaaca tatttttatt
    65221 aaccttaaag ttatgtttta catctattat tctagccgaa gctgggatta tgtattctaa
    65281 ctcttttaaa gctttttcag ataattcttt ttttaactct tctttattcc tttttacttc
    65341 aacctttttt gtttcataaa aagtactcgt ttttatcttt attggaaaag tatagtttcc
    65401 tattgatagt tttttttctt tattttcaac aacataatct ttatatttta tattttttct
    65461 cattgtaaac tctttatcat aaaaacttag tgtatatata tttttctttt ctccagtttt
    65521 tttatttaca gtatctacat aacttgcctt ttttgtggac tcataaaaag tacttgccca
    65581 tacttctggt attgacttgg tattagctcc atttaataag acatctccct tttggactat
    65641 gtctccagat ttaataactg atttaccact tctagggatt accttttcta ttataccatt
    65701 ttttaaagca attacattac aataatttga ttggtctgta gattttaggg attctgcctt
    65761 ttttgtaaca gtaacaaata tatttgttcc ttttacattg atagataaat atgccacatc
    65821 attaaatttt gacatcatat ggtctctaac ttcttttcta tcaatactct tcttatagac
    65881 tcctggcctt actccaacct tataaatctc atttctaaga gcttcttttt ttataccttc
    65941 aggagattgt atatatacat ctgtcacaaa ctgcgatgta gacatcaata aaaataaaga
    66001 aacaagagca caaatccaca tacctttgtg cttataaact cttttgataa taaaagggac
    66061 cccagttttt tgctttacct ttatatcaaa cttacttcct ctataaacat tcttaaagtc
    66121 ttttatatct tgtctatcta tatgaaactc cattttagta ttttttattc tagttacatt
    66181 gtaaacactt atcccatttc ttataagatg atttaaaaat tgttcgagtc ctactccttc
    66241 cacaactata acatagtatc cccttataaa acttatcaag tgtatctcct cctaatcaac
    66301 atactcaaca ttgtagataa tcccttttat acctatctca ctatcagtaa tatacttaag
    66361 tgaaagttta tccccagata ttttaattgt tttaacttta gtctttattc ttattaaatc
    66421 aacttcatat tctaatattg atagataatt ttctatacta ataaacgtat tacttgtaac
    66481 agtaataact ggttgattta cttgtaaatc agtggatatt tctaacataa gcattacccc
    66541 cttaattaat tttatgcttg aaataggtat ttatgcactt tattgatgtt gtaacagatt
    66601 agttttaaaa tttttatata ataaatacct aatatctaat atattattta aacaagaaaa
    66661 aggtaatcat attgataaaa aatcaacatg attacctttt tattttttct tatataaaat
    66721 ctaaacgtat acaattttta ttaatcttgt tctattaaac catatccacc agctttacgc
    66781 ttatacacta tgtttatttc aaaattatct tggtttctaa acatatagaa attgtgtcct
    66841 actagttcca tttgaagtat cgcctcctca gaactcatag gttttacatt aaatttcttt
    66901 cttctttcta ttactatatt ttcatcttct tcatcatcat aatcataatc atcaaattca
    66961 ctgctattat ctataaagtc aagattttca aatcttatgc tcttattatt ttgaactttg
    67021 tctttaactt tagttttata tttgacaact tgtctactta atttgtcaca aacaatatca
    67081 attgctgcat ataagtcatc ttctacatct tctgctctta ttatttgacc gttaatagga
    67141 attattgtaa cctccacttt ttgtctatcc tttttcgcac ttactgttac tttcacttct
    67201 gattcaggat caaggtattt ttctaaccta cttaattttc catctacgta tccttttatt
    67261 ccgtcagtta atttcatttg tctcccagat actattattt gcataaaaac ctctcccttc
    67321 aagcctttcc aattctaata ctttaatatg ttaatcttta aatacaattt ttataaattt
    67381 attgtattta aattaatatt attgtatatg aaaatgatta tttttaatag tctatttatt
    67441 tttcgtttgt tatgatatta ttaaaagtac agggtaattt acaaaatctt tacattctat
    67501 ttattaataa accatataaa atagttcaaa aatcctgcat aaacaagcca cattaaataa
    67561 atcaaattta tgtatccaga tctcttatct attttagaaa acttcgaaat cattattata
    67621 gaaaccaaaa tcattattat tatatctatc aaagctgtaa atctaagtcc aaatccaaaa
    67681 aatagtatac tccaaataaa gtttaataca agttgtaatc cataataaaa aattgcatct
    67741 cttactttag gtaagttgta accttttctt aatattaggt atgaagatat acccatcaat
    67801 atgtacaata tagtccaaac tataggaaag ataaaagctg gtggtgcaaa gcttggcttt
    67861 gtgagttgta aataataggt tgaaatatct gttccactga taatcattgt taagatgcta
    67921 cttaagtaac ctattattag tggtataaat atgtttatca aaaaattcct aatctctttt
    67981 actgatataa tcaaattttt ccccttcttt caaaattttc tttgattata gatatgctca
    68041 aatatgactc gttattccca aaaactataa aaagcctaga gatttctctc taggctatat
    68101 caatctattg taagttttgt tttaccaact tatttataag ttttccgtca gctcttcctt
    68161 taacttttgg ttggataact gacattattt ttcccatatc cttcatagaa gttgccccta
    68221 cttcagatat agtagatttt acaatttctt ctaactcttc ttcgcttaat tgttgaggta
    68281 ggtactcttt taaaacttca atttcacctt ctgtttcttt tattaagtct tctcttccag
    68341 ctttttcaaa ttcaactaat gcatctctac gttgctttaa ttgttttgct attacatcga
    68401 taattccatc ttcatcaagc tcgaccctat tatcaacctc atactgcttt atagaagctc
    68461 ttattaaagt tactacagat tttctcactg tatctttgtt tttcatcgaa gatttcaaat
    68521 cctcttgtaa cttttgctta agggacatcc ccttcacctc tttattctta tttactacta
    68581 tttcttagcg ttttttcttc ttgctgcttc agcttttttc ttacgcttaa cgcttggctt
    68641 atcatagtgc tctctttttc tcacttctga catgatgcca gacattgcac attgacgctt
    68701 gaatcttctt aaagcgctgt ctaatgtttc attctctcta actcttactt ctgacatttc
    68761 tttttccctc cctccaatag cgcaattatg ctgggactgt aactatgttc tttttgcata
    68821 atatgcatta caacctaaca ctttgtttat tataaactaa atttttactt ttatcaagta
    68881 tttttatcaa gaaggaactc aatttttcaa taatttagtt tagttttgtc ccgcttcgta
    68941 attaggaagc tttttaccag ctaaaatatg atagtgcaaa tgtttaactt cttgccctcc
    69001 atcacttcca caattattta tgactctgaa tccagtttgg tcaaaacctt tctctttagc
    69061 tattttatta ataacaacat gaatatgtga cacaatgtcc atctctttat caggaatatc
    69121 aattaaacta tcataatgtt ttttaggtac aactaatata tgatatggag caactgggtt
    69181 caagtcatta aaagctaaga ctctatcatc ttcataaact ttagttgaag gtatttctcc
    69241 gttcgctatt ttacaaaaaa tacaatccat tctttccacc tcctatctta taaatattat
    69301 aatttctaca tgttatagca aaattccttc tacatattca tcttttacat catttatttt
    69361 cacttttaat atctgacctt gtatattttt gtcactttca acaacaactc ttatataatt
    69421 tgaagttaat ccctcatatt tattgccttc tatattttgt tcaaacaaaa catccaactc
    69481 acggccgata aatttagttg caaatttatt aaaatttact ttacttaaat ttaaaagttg
    69541 ttcacttcta aagtgtttca tttgagggtc aacttgattt tccatagttg cagctggagt
    69601 tccttttctt ggtgaatatt taaaaatatg catttgtgaa agctctattt cttttaaaaa
    69661 ctcgtacgtt tttttaaact cttcatttgt ctctccagga aaacctacta ttacatctgt
    69721 agttattgcc acatctggca ttttacttct caatctatct acaatagttt tgtactctaa
    69781 agttgtgtat cgtctattca ttctttttag agtttcatca catccacttt gaagtgataa
    69841 atggtaatga ggacaaactt tatccatctt taaaacttca tttacaaatt catctgtaaa
    69901 taaaattggt tcaacagaac taagcctaat tctttctatt ttttctatct ggtttatttg
    69961 ttttattaca tcaagaagtt taatatccct atcctttaaa tcttttccat aagaggcaac
    70021 atgtattcct gttaatacaa cctctttata gccattatta gccaattttt tcacttcatc
    70081 gactatacta tcaatatctc tacttctaac gcgtcctcgg gcataaggaa tgatacaata
    70141 agtacaaaat ctgtcacatc catcttgtat tttcataaat gctctagtct ttccattagt
    70201 ttggctgatt tctatttctt caaaagcttt aactttcatt atgtcgtcaa ctgtactaac
    70261 tttcttactt gaatttatct ttttaatttc ttcaacaatc tttcttctat catttgtacc
    70321 catgactaaa tttacttctt ctatatccaa aatttcttcc ggagatacct gagaataaca
    70381 tcctacaacg gctattattg catctggatt cttcttttta actcgtctta tatattgacg
    70441 agattttcta tcactcatat gagtaactgt acatgtattt ataacataaa catcagcata
    70501 ctcttcacta ttgacttgtt cataaccatc tttctcaaat agttctagca tagcttctgt
    70561 ttcatattga ttaactttac acccaagtgt ataaaaagct acttttttca atttattttt
    70621 ctcctcctaa atcacttagt tcatacaaag ctattgttga tgctacaaca gaagctgtct
    70681 cagttcttaa tattctaggc cccaatgata caacattaca attatttttt tgtatttgtt
    70741 ctatttcttc ttcagaaaat ccaccttctg gacctataaa aattccaaca ctatctatat
    70801 tagaatcaca tttttttagt gcatgtttta ttgaaactgt tctttcattt tcataagggc
    70861 aaatatttac attatttttt ttcatatctt ctaaagcttc tttaaaactt aaaacacctc
    70921 ttaattttgg tatcttacct cttttgcttt gctttgctgc ttcataaatt attctttccc
    70981 aacgttcaaa ttttttatct tcttttttgt catcaacttt aacaacactt ctcttagttt
    71041 gaactaatat tatttcttct acacccactt cagttaattt ttgaagtatc atttccattt
    71101 ttggagcttt tggaagtccc tggtatagcc ttactttaag ttctgattct ctatttatat
    71161 caactttttc taaaatctct aaattaacta tactcttatc tatattcatt atctcacaaa
    71221 tatactcatt attattcttg tcacatattt caagtttctc acctaatttg catcttaaaa
    71281 cttttgaaat atgttttaca tcttcacctt ctatagtgca agttttatct tgtagattta
    71341 tattattttt ttcaacaaaa aatctatcca ttatacgtca ccatatccct tattttttaa
    71401 gcttagaaac tattgctgac cattcaccta atttttgaac ttcaactatt tcaaatccat
    71461 tttcaattaa gctttcttta acttcttcta ctttatccaa aattatacct gaagatatga
    71521 atatagcatc ttctttcata aagttttgaa catcttttgc aagtatcttt attatatcag
    71581 ctattatatt tgcaactatt acatccgctt tatcttttat tacatcggtt aaattaccat
    71641 gcattacaga tacacttttt tcaactttat tttcaagaac attttctttt gcaactttta
    71701 cagccacttc atctaaatct acagctacaa cttcttttgc tcctaatttg gctgctgcta
    71761 ttgcaaggat tccactacca catccaatat caaatacttt agaatcttta ttcacatact
    71821 tttctaattc tctaatgcac atactagtag tctcatgtgt ccctgtacca aatgccattc
    71881 cagggtcaag ctctatgatt aaatccccct cttgcatagc ataatcttcc catgtaggtt
    71941 ttactactac cctttgtccc acttttgttg gtttgtagta tgctttccat gcatttgccc
    72001 aatcagcttc atttacttgg tccaatgata cacttccttc acctatatct ataccaaaac
    72061 cttttaatcc taaaactttt tgctttatta tttcgacaaa ttccatcaca tttttttctt
    72121 cagaaacata agtttttata agaacatcat cttcttcatt ctttttaaat acttcttctt
    72181 caacataatc ccagtctagt tcatttttct tttggaataa aaagtctttt gggtcttcta
    72241 ttacagctcc tccagctcct tgttcatata gtatattcgt tataggttca actgattctg
    72301 ttgttgtttt tatagttact tctatccaat tattcataag tttacctctc ttctctatag
    72361 taatattcct gtttttccat aacttttatt atatcataaa tataatattt tgttgtttta
    72421 tattattggt tttaaattca atctaataat atccttatat aatagtcaga atatttaaaa
    72481 atccgattag ttaattttaa acctaataat aaaacttcta ttatatctac tatatcaata
    72541 tttgaaatcc acttagttaa tcttaaacat acaaaatctc caacttataa ttattttcgc
    72601 gatgtacctg aaacccactt agttaatctt aaacctcaaa tttattatct atatacactt
    72661 gtaaacactc tatctcacaa cttatttttc cttttaaaaa atagttttta cagtagactt
    72721 acagtagtac tttttgtatt ttcaatgtct aaaggtatat tatatttaaa catatgctca
    72781 cttcaaaatt aagcctacag tactattata ctcaaactta ctactagatt ttagtaccat
    72841 gtatccttct actttgctta ttaatccata ataatataat ctattaaata taaaccctga
    72901 tacttgaatc gaatcttgtt gtaactccct atcttcctta taaaaatctt cttccagaat
    72961 aattttgtaa ctaacatcaa catctctaaa aattttagct gcttccttct tactatcaac
    73021 aatatttttg taaggttcaa aattaaaaat taaatccaat ccatcaaaaa tttctttatt
    73081 tataccataa atattcttaa tttctttatc acaacttata aaattctctt caaaatattt
    73141 tttaactaca ctattatcat agtaatcatc caaaatagtt tttctaatcc ccattgtaaa
    73201 aatagagtta gtttttaata tgtcctttaa gatgttttta gttgtgttct taagtttgtt
    73261 atcataaatt ttatcttcac taggtagaat ataaaagttt ccatattcat atttattatt
    73321 tctattacat ctacccattc tttgtatcaa gctatccata gttgctaaat cacttattat
    73381 tatattgaaa tccaaatcca aggatatttc tactgattga gttgatatcc aaatatcacc
    73441 ctctccattt aatattttac tatatttctc ttttttatct ttgaacttaa atctactatg
    73501 taaaacatct atatctacac caccatactt atcagataaa ttttctttta aaaactcata
    73561 tgttctattg actgaatcaa tagtattctt tattataaga attttttgtt tattttctaa
    73621 agcatcttca actattgact tgatttcttt ttcctttata aaagaaacct ttacatcttt
    73681 accttcacaa atctcttctt ccttgttgct ctcaataaaa actatttctc ctttatcagt
    73741 aacattttca ttactttctt cttgaaaaat aattcccttg tttatcattt gctctttata
    73801 tgattttgga agtgtagctg tcattaagtg aaaatcaaca tctaagtact tgcatgcaaa
    73861 ctgcataaaa tatatcaaaa tcaaaaacat ctttggttcc aataaatgta cttcatcaac
    73921 agttatagat gcatttttta cggctgcgaa tattttttca tatcccggaa atttaaacat
    73981 actaagtaat aactggtcaa ctgttgcaat tacacaaggt ttacaaaagt ttatactcaa
    74041 atctatatcc cttaatgtca atacaaaatc atgttctcca ttatcttcat tctctgaata
    74101 taagtttata tctccatgaa gtaatccaat gtaatcatta ctacttcttg tatctaaatc
    74161 atttttattt tgaaaaatat tttttctata aaaactttct gctgatattt tatttggcac
    74221 taaaaagaat tttcttttaa aagtctttct ataatctgca gctgtttttc ctgaacctgt
    74281 aaatgcaaca gtcagaacat ttcttccaga aagttctctc aacctttttt gtatagtatt
    74341 gaactctata ttattttttt ccaaattacc ctgactctta tatatctcat ttaaaatcat
    74401 attatcaatt tcttcatcag taaaatcgtt ataaaatttt atacctttct gtctacttga
    74461 tgcactatgg tctattaagt tcagcatccc tttatataaa atatacttaa actttctata
    74521 atttaaaact gaatcatcta tttgaccatt gttataatca ctgtctataa acatactttc
    74581 acttaattta tctatgtaat cataatccaa tacatcttca ccaaatttaa agtctacatt
    74641 taaaatgcta tttatataac tttctatatc tttcagatta aactcttctt tttctaaaat
    74701 gcctttttca atatactcat aaatttcttc ttgaacttta ctaatactta acctcatata
    74761 atcttcatag tttccatgat gtaacattat acttttatat atatataact tatcttcttc
    74821 tgacaagttc attttttcta atatatcttt taaaaatgct ccagaaaata tattatgtct
    74881 tgctatcttt tttaaagatt ttttgtcaga ctctaacttt ttcctctctt cttctgagca
    74941 actatacgat attttattat taatctccat tttttgttgc ataattgaat taatttttcc
    75001 taaatcgtgc aaagcacaac atatttttag tatctctaca tctttatctg aatatagatt
    75061 tagttctaat atagattcta atacttcaaa taaatcctta atatgttcaa ctaatgtttg
    75121 ctcttgttga ttagttctta aattatatga cttagctaat atttcttttt gcatgatatt
    75181 tttcatgata aacacctatc tttcaaaata atttaaagcc atgtaaaaac ttcttttgta
    75241 tcaatacata catttacctt aatattttta ggatatatac catcattatc aacatatata
    75301 taatggcaaa actcataaac tctatcatct ctatttgctt ctaaatcttt atatttataa
    75361 ggtaatgcaa tcaatacacc ttgatttatt atagtctcga cattctcttt atctcttaag
    75421 tcaactctta catatgtatt ctttaatttt atattttctt ttatagcatc acgagtattc
    75481 ataggtataa cctcttttaa ctcaacttct ttcacaaaac accctttttc acttggtatt
    75541 acaaaatctt cttttcttcc taaatttgca tatttacatg gactttcaag cttttttcta
    75601 ataaattcaa gttcttcatc atccttgcaa gaaataaata tagtcagttc tacttcttta
    75661 agaacttcat agtttaatat gctattttga gctttatgtt ctttatagta atcatagtag
    75721 tttccttgaa gcaaaaactt ttctttatct ttgccttttc tcatatttgt atattcattc
    75781 caaaaatcaa tgttctctcc tcttgaaaat tctagttctc tatgatgatg tgttccaatt
    75841 attcctatat ctatatcaga gtttaatctt ctatcacata aatacgttat cattcccatt
    75901 attgtggtct tagatggtaa atttaaagta cttatatatt cattttgaaa tacttttggg
    75961 tctctatagt gagcagttgg ttgcttaagt ttacattgta atactttcat aattcaaaaa
    76021 acctcctact cttttaaata ccacatatta tcttctccaa tttccaatct atctgctaga
    76081 tttttaatct cttttacagg gtatttactt aaattaaact tatttaattc ctttttatta
    76141 gaaattttta atctgtcat
//
LOCUS       DAFAZV010000018        74845 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFAZV010000018 DAFAZV010000000
VERSION     DAFAZV010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 74845)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 74845)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..74845
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.018"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..321
                     /locus_tag="KOU88_001742"
     CDS             <1..321
                     /locus_tag="KOU88_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3211635.1"
                     /translation="IALKNITIIIKKYLKKDMLMIRYGGEEFLILSVCKDYKKSKIFG
                     RKLCRIVKKFLNNNLTVSIGIDTCKNSSIDIKEIIENADKALYKAKESGRNRCLHYHD
                     FKNF"
     gene            348..2233
                     /locus_tag="KOU88_001743"
                     /pseudo
     CDS             348..2233
                     /locus_tag="KOU88_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897561.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
     gene            2241..4241
                     /locus_tag="KOU88_001744"
     CDS             2241..4241
                     /locus_tag="KOU88_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3211636.1"
                     /translation="MILLRKKIGIIASDIELKERIEELYREDVENGTIIIDILNLDLM
                     ENQGRILVEKGAQAIIGRGGGYSLVIDTVNVPVIPMNMKSTDLLRAIEIAKKYSKKVV
                     LILGDNEVSFDYVGWRNVISTEITEEWFESKYEIRSKVVKYIDQKDEVVIVGGGLACS
                     FARQYGIDSVFATASDESIREAVEYCKKLLDTLGEEKFNNEVLRNILDGIKDGVIAID
                     SNGSIILYNESAKNMLKVERKCALNKYILDVFPKMEWMLDCLHEKEDVEDRKIRNINN
                     LIVNTRTTLIKVDNSTYGVLGIIQDITKLQNLERKIRFDLNQKGLYARYTFDDFLFKD
                     KLTKEFIEEAKKIGKSDYTTLLYGESGSGKEIIAHSIHNISKRKDRPFVAINCATIAE
                     NLLESELFGYEEGAFTGARKGGKRGLFELAHGGTLFLDEINSLSFNIQTKLLRVIEER
                     QIMRIGSDYIIPLDIRIIAATNESLTEKIVMGTFRADLFYRLSSLEINIPPLRDRRED
                     IIPLFNNFVNEVLKDDGLNGINSIDENFVLTKDEMDKLYNYSWPGNVRELKTIAQKYV
                     VTGKIKLRQDRDFKTKKLLPNSEVDKFNSETTASVEVQDESINISKINDGKISIDIKE
                     VNKYVEEKIISMLFAQGLSKNEVAQVLGISRTSLWKKYNKNI"
     gene            4503..5762
                     /locus_tag="KOU88_001745"
     CDS             4503..5762
                     /locus_tag="KOU88_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBK3211637.1"
                     /translation="MSQSMVGKHAMWPKENDVIFSISGRAQAAEKAFGMDNVINATIG
                     ALMDDSGKLITMKTVYEEYKALDNCEIGAYAALEGQPDYLEAVKKVFFRDYLPEGHIR
                     VLASPGGSGAIKLAVWNYTNEGDEVLTSDWFWSPYVSIAEEANRKVVNYQLFDENRRF
                     NFESFKEKFVNIAEKQGRVFTIINTPAHNPTGYSVADDEWDKILDLSKEVAKDKDKKI
                     IFFVDSAYIDFAGDDDVCRKFFKKFSNLPENVLILVGFSMSKGFTAYGMRMGAIICIS
                     SSEDVAEEFHYSCVHSCRANWSNCNRSAMAVLSNIVNDPKKFKEYEDEKEIYKNMLTR
                     RADVFVKEAERVGLEILPYIAGFFVSIPCDNPKEVCEELTKHNLFAVPLKMGLRFAVC
                     AVSEDKCKKAPSIIKEALESLEVKINN"
     gene            5823..7610
                     /gene="iorA"
                     /locus_tag="KOU88_001746"
     CDS             5823..7610
                     /gene="iorA"
                     /locus_tag="KOU88_001746"
                     /EC_number="1.2.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate ferredoxin oxidoreductase subunit
                     alpha"
                     /protein_id="HBK3211638.1"
                     /translation="MKQLMTGNEAIARGAYEAGVKYASAYPGTPSTEILENIATYKDA
                     IVAEWAPNEKVALEAAIGGSIAGARTMASMKHVGLNVAADPIFTYAYTGVNGGMVLIT
                     ADEPGMHSSQNEQDNRMYAKFAKIPLFEPSTSQEAKDMIKEAFEVSEKYDTPVLYRVT
                     TRLCHSKGLVECYDREEVEIKEYVKNAKKMVTVPANAQIRRGVVEERMEILKKFSNET
                     DLNYYEINDTKIGVIASGMCCNFAKEVFGKNASYMKLGFTNPLPYEKIKEFAEKVDKI
                     YVIEENDPFIEEQIKAYGIDCIGKDVIPPYGEMTPDVLRKAIFGKTNDTIEYKSELVT
                     PRPPSFCAGCPHRGFFYELGKRKNLIVGGDIGCYTLGFAPPYNGIDYVVCMGSAFGTA
                     HGAQKVLNMKDDNEKRLVGVLGDSTFFHTGINGLLDVVYNRGNSISVILDNRITGMTG
                     HQENPGSGYTLQGAKTKEVDIEGLVKACGIEHVRVINPNNLKEVNEALDWALAIEDEP
                     SVIITRWPCVLKKFSKEDIEEFNNPFKTKCKVEHDKCIGCKLCLKTGCPALSFDKENK
                     LSNIDRNQCVGCGVCAQVCPKQAIVKEEK"
     gene            7612..8187
                     /locus_tag="KOU88_001747"
     CDS             7612..8187
                     /locus_tag="KOU88_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indolepyruvate oxidoreductase subunit beta"
                     /protein_id="HBK3211639.1"
                     /translation="MTKSILLVGVGGQGTILASKLLTMGLMEAGYDVKMSEIHGMSQR
                     GGSVSSQVRYGDCVHSPVIEIGGADILVSFEKMEALRWFNYLKPEGKALVNNHRIDSM
                     TVLIGGAEYQESDIDAELSRLNAKVINAADKAEELGNSKIMNVILLGCLVKSMQLESI
                     DWEKIISENVKPKFVELNIKAFHEGMEMVSK"
     gene            8240..9310
                     /gene="buk"
                     /locus_tag="KOU88_001748"
     CDS             8240..9310
                     /gene="buk"
                     /locus_tag="KOU88_001748"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBK3211640.1"
                     /translation="MTYRILAINPGSTSTKIAVYDGEEQILVKTIDHPAEEIAKYNTI
                     QDQFEMRKEAVLNILKENSIDLKSLSAIVGRGGVLPPVKSGAYLVNEEMIDVLRHRPV
                     LEHASNLGAVVAHAISEPLGINSYIYDSVAVDELIDVARISGLCGMDRSSAGHALNTR
                     AMALKYAKDKGKDYKSLNLIVAHIGGGVSIYLHEKGRMVDMLSDDEGPFSPERSGRVP
                     ATKLVAACYSGQCSEREMTKKIRGKGGIVSYLNTVDAREVEKMIAEGNEEAKIIYEAM
                     AYQLAKGIGELATVVDGKVDAIIITGGIAYSEMFTSMVKKKVEFIAPVEIMAGENELE
                     SLAFGTLRVLNGEEEARIYSEN"
     gene            9528..10229
                     /locus_tag="KOU88_001749"
     CDS             9528..10229
                     /locus_tag="KOU88_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211641.1"
                     /translation="MGKISLKSMIRLFSGFFIFAISSVLMINAHVGLMPWDVLHQGLS
                     IKLGITIGQASIMVGVVIVILDAVFGENIGWGTLLNMTFIGIFIDLVIFSGVIPHASN
                     TYIGVFMVVIGIILAAIASFLYLGVCLGSGPRDGLMIALQKKTNKSVRLVRTILEILA
                     LVVGWLLGGSVGIGTLVSALGLGYVLQIVFRIFKFDTKLLKHRFIIDDIREWKEKKSN
                     EHKCKSSIVIKNEQN"
     gene            10289..10795
                     /locus_tag="KOU88_001750"
     CDS             10289..10795
                     /locus_tag="KOU88_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBK3211642.1"
                     /translation="MELWDLYNADGIKTGNVIKRGNSIEEGYYHLAVEVWILNSNSQI
                     LIQKRSKSKKTLPNMWGMTTGCIVSGEDSLEGAIREAKEEIGIDITKDEMKVFRSMIH
                     EDTLWDVYLVKKEYDISKAILQEEEVSDIKWVSTDEIRQLLKEGLFFEYPEIYELLYE
                     IDNNKLNI"
     gene            10970..11992
                     /locus_tag="KOU88_001751"
     CDS             10970..11992
                     /locus_tag="KOU88_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK3211643.1"
                     /translation="MEDNKGLARDSSKYKIVSISVVVIILITFWYMLNMVLLTFIMTF
                     IFYNLLVATRKRIKKFSSLNIPDSLIIIVLYALFAILLVLISYAVVPIIIVQLTELSR
                     VFSDFDVNQFAQSLGPKLYPIVSKLDFNKYISQAGLLIASTATKVGSFGVNILLAFLL
                     SLLLLLEKNEIKNFGDKLSDSKISFIYNSLVFFGKSFVKNFGEVMKVQVMIAFINSVV
                     SMIFLGFMGFPQIWALGFMIFVLGLIPVAGVIVSLIPLTVIAFNTGGITKVFGVLLMI
                     CIVHAVETYILNPKLMSNRTKLPVCFVFIILLVGEHYLGVWGLLIGVPIFMFLMDILG
                     VKFTSR"
     gene            complement(12139..12447)
                     /locus_tag="KOU88_001752"
     CDS             complement(12139..12447)
                     /locus_tag="KOU88_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBK3211644.1"
                     /translation="MKNNNLNCAATNCAYNTSGYCYAGSIKVDGMQATTTENTYCASF
                     EDKYTSGITSRSNETNQVDTDNIHCEAVKCKYNKNELCKAEKVHINERNASCETFEMK
                     "
     gene            complement(12507..12935)
                     /locus_tag="KOU88_001753"
     CDS             complement(12507..12935)
                     /locus_tag="KOU88_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211645.1"
                     /translation="MNNKLHELEKNLPETSCSFCTHLSFKGPSLDYRYDIRCVISDTK
                     PDFRGCCEYFEPEYTELNTGDLDNLYINFLETCLKVNYNDYINSMYWKLFKERTLLEN
                     NFKCSICGSTENVDVYHVNKNLGRETSKDVVVKCDKCNCK"
     gene            complement(13158..14615)
                     /locus_tag="KOU88_001754"
     CDS             complement(13158..14615)
                     /locus_tag="KOU88_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein A"
                     /protein_id="HBK3211646.1"
                     /translation="MTTFLIGLAILLIGGALYGAYCEKVFGPDDRKTPALAQSDGVDY
                     VPMKKWKNSLIELLNIAGTGPILGPIQGILFGPIAFILIPIGCVFGGALHDYMSGMIS
                     IREKGAQMPSLISRFLGNKVFQVYNIFLCLLMLLVGAVFIYTPGDLVVTQILNMKSTI
                     NNPVVWIVYGLIFLYYLCATLFPIDKIIGKVYPIFGAILLLSAAGVGIGIFTQGYDLA
                     NLSLANWKGIHPDGIPLIPTFFVTVACGIVSGFHSTQATLIARSVSNEKEGKTTFYNM
                     MILEGLIAMIWAAAAMGIYNKGIPKELVGSPDVIGLVARDLLGSIGGIIAIIGVIVLP
                     ITSGDTALRSLRLMLADYFHYDQKEKKHRVILSICIFIPVIAILIFAKLSASGFNILW
                     RYFSWSNQTIAIFAFAMITVYLIIKEKNYIISLIPGMFYSFVIFSYIFNAQIGFNLNI
                     NISYVLAAIFTVLYAILTVRSGRKLKSKADTKLAD"
     gene            15032..15946
                     /gene="nadA"
                     /locus_tag="KOU88_001755"
     CDS             15032..15946
                     /gene="nadA"
                     /locus_tag="KOU88_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBK3211647.1"
                     /translation="MDKDLTYQIKELKKEKNAIILAHFYQPPEIQELADAVGDSYYLS
                     EIARDCKEEVVVFCGVRFMGESAKILSPEKTVLMPVSNAGCAMADMVDEEGVIKLKQQ
                     YPNALVVCYINSTAKVKAHCDVSVTSSSAIKILENIDNKEIIFLPDKNLGGYIAEQFP
                     DKNFIFWDGYCKYHNNIRAEEIIELKDKYKNAEVLVHPECKKEIRDLGDYVGSTSGII
                     KYATNSKNKDFIIATEEGILHELKKNNPNKNFYIPGGKILCTDMKKTTLENLYSTLKN
                     MENEVIVEDEIMEKALNSLLNMHKLAEG"
     gene            15959..17260
                     /locus_tag="KOU88_001756"
     CDS             15959..17260
                     /locus_tag="KOU88_001756"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBK3211648.1"
                     /translation="MNLEQDVLIVGSGVSGLYCALNLDKSLNVLVVSKSTIENNNTYL
                     AQGGISTARNIDDIESFVEDTMKAGQYKNRVEAVQVLADESIENVGQIVEYGMPLDKE
                     NGEIDYTREGAHSVNRIVHSKDNTGEVVFKTLLKEAKTRENITLIEDAYLLDILKDGN
                     KCIGARIFKSKKEIHVFSKIVVLATGGIGGLFKNSTNQRHLTGDGIAIALRNNIKIEN
                     LEYIQIHPTAFYEENNEGRRMLISESLRGEGAKLLNKNKERFVDELLPRDVVSKAIFE
                     QMEKDKLPYVYLDATHLDSEYLINRFSFIYNECLARGTDITKECIKVSPAQHYFMGGI
                     HVDLDSKTSMENLYAVGEISCTGVHGANRLASNSLLEGLVFSKRAAKNINSVIDNVKV
                     KFIDVPDMDIDIEQVKKENKILVIKEIERTSEDFGDELFDY"
     gene            17241..18077
                     /gene="nadC"
                     /locus_tag="KOU88_001757"
     CDS             17241..18077
                     /gene="nadC"
                     /locus_tag="KOU88_001757"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBK3211649.1"
                     /translation="MNYLIIDRMIQDALIEDVPSEDITTNSIVDENSKSTVDLICKQD
                     GIIAGLGVFKRVFEILGDVDVKLYKNDGDRVKNREKIAVLTGSTRNLLVGERVALNYL
                     QRMSGIATITSRYVEKLEGTNTKLLDSRKTIPNLRILDKYSVKVGGGCNHRFNLSDGI
                     LLKDNHIGAAGSVKKAVELARKNTSFVRKIEVEVETLDMVKEAIEANADIIMLDNMSL
                     EMAKQAVDIINGRAIVEFSGNVNLDTIEDIGKIGVDVVSVGALTHSVKALDISMKNLR
                     NI"
     gene            18333..18665
                     /locus_tag="KOU88_001758"
     CDS             18333..18665
                     /locus_tag="KOU88_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBK3211650.1"
                     /translation="MKVAYIFSSTNTHKILDKMIIPQLEQGTHGVDVLGMFFFMDNTL
                     FLSKGNPVGERLSKLHEKTDMIIMACDQCAIERGIENNLVDGATIGCFPNLYACLGSA
                     GVDQVITL"
     gene            18827..19012
                     /locus_tag="KOU88_001759"
     CDS             18827..19012
                     /locus_tag="KOU88_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211651.1"
                     /translation="MSEKYADKLEIKLYQAGKDFSYIKKYGIITKGTLIINQKKKYDR
                     LNKDTIERAIVEAINNN"
     gene            19039..20124
                     /locus_tag="KOU88_001760"
     CDS             19039..20124
                     /locus_tag="KOU88_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBK3211652.1"
                     /translation="MNILEIVLNGVKDTIVASIVTLNGASGWLMISFILAGVLHNVLT
                     PRRFQKQLGNKKFSSLIKSTISGMFLPICSCGVIPLGISMYYSGAYLGPVLAFMTSTP
                     IINPIAVVLCLGLLGPKVTIIYLIAGFLVPFLVGFLGNCFGKEELSLHNDSEEEVIEL
                     EEEKRSFMGNMIDGLKWSFGELALTISKYVVMGMVFAGFITTIFPNSIIQRYLGNPGL
                     LSLGSIAILACVMYVCAVGHIPFIAALVASGASPGIAITFLIAGAATNLPELISMFKL
                     IGKRTVIIYSVTLTLSSIIIGYITNLLLVNNNSVNLDATNSSIQLANKLMLNIPDSFE
                     YVCTILIILFAFKSIIPKMKEVIGNHA"
     gene            20117..20575
                     /locus_tag="KOU88_001761"
     CDS             20117..20575
                     /locus_tag="KOU88_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211653.1"
                     /translation="MLKKIVIISCIVVVLIILSKIVDDNIKEDASIPNVNKETLEYFR
                     KNYKEDIITCAEEDLNNDGKKDLVVIYKKSNNSNEMVVVVSDKNSHYITKPIPAPIEN
                     QTITFKNIDDKAPIEVIVSGSKNGNVGYAIYRVEGKKFVDLFGEDMDKCC"
     gene            20610..21701
                     /locus_tag="KOU88_001762"
     CDS             20610..21701
                     /locus_tag="KOU88_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3211654.1"
                     /translation="MKLSKKIQALILFGVMGTSILTGCSSKPKEKEEAKTGKDDYTIT
                     VGYYNCDHMTAGPVAESAGIYKDLGLNVKTVGNGKVPEAMAAGKMDAGYIGTKGLVGA
                     IPKGSPITIAANNHTGGSEYLIVSKDIKEPKDLIGKKIATDMSDFLWTSDYGPETGLP
                     TDPSKYEVVNMDSDKDKYLALKTGKIQAFTSCDPWGSVAENDGAGKIIASTQYKEKAN
                     GKEYNCCSFSLNKNFIKEHPDLAKKLVLAHTKAIEYIYTNPAEAAKIFAKYYNVEEEV
                     ALRTIYKKTVGEGRTLTWKVTGEEYKNNLQMYKDLKALDDIPKYEDTIDTSLLDSCGA
                     DDFDKFIKEKVNPEFPEGMSYEDWKAKVL"
     gene            21706..21930
                     /locus_tag="KOU88_001763"
     CDS             21706..21930
                     /locus_tag="KOU88_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211655.1"
                     /translation="MENMKNIIILFIIILGSIFIIFFNFEDKEEIKGKLRIGVSDDTS
                     GFVINYMVNRDYFENIKVSDIMDIFTINDC"
     gene            21940..22503
                     /locus_tag="KOU88_001764"
     CDS             21940..22503
                     /locus_tag="KOU88_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211656.1"
                     /translation="MQWALSSEEIDIAIICKDAAKQYVNVNSGFEIVGTVVQNSDIFL
                     LSDNNPEKIGVIQNRDYQSELVKKYYKNVEVAPLLGTALAYGLESNLVDGVVIDCIKS
                     IGLEGKRKSTTKLGDYDTYVLVVNKEFKKSKAYSDFITLYNKSVDALKNKATFKKVLK
                     EYRNIRNIDMEEISNWKLKFLKIKAID"
     gene            22464..23093
                     /locus_tag="KOU88_001765"
     CDS             22464..23093
                     /locus_tag="KOU88_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211657.1"
                     /translation="MEIKISKDKSDRLTKKKTDGSMDILYKIILLVIIFLVWHFAAKD
                     IGSSLLLPMPVDVIKGFFFCVTDAETVTNLFITLQRVLKGFMYALLFGLPIGFIMGFS
                     KTFERVLSPVVDSVRQVPIMAWVPLTIVWFGIGDGPTIFLIAFSGVFPIILNTIQGVR
                     AISKDYYNAARSMGASPIVIFTNVIVPASLPDILTGSRIAISTGWMSVI"
     gene            23270..24022
                     /locus_tag="KOU88_001766"
     CDS             23270..24022
                     /locus_tag="KOU88_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211658.1"
                     /translation="MKLSVRDINKTFVNNRVHTKVLEDISMDIDDGQFVCLLGPSGCG
                     KTTLLTIIGGFQKSERGDVFINDKRVKKPGIDRAFIFQNYALFPWKTIRGNVLFPMKQ
                     QKIPKEKREEMLEELLVMSDLKGKEKLFPHQLSGGMKQRVAMIRALACNPEVLLMDEP
                     LGAVDFQMRQNLQEELERIWIKKKITALMVTHDVDEAVYMSDRVIVMSRDKGRIIDDI
                     NIDIPRPRIRGSQKYEEYKNKLTDTLSKCYEV"
     gene            24035..24520
                     /locus_tag="KOU88_001767"
     CDS             24035..24520
                     /locus_tag="KOU88_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211659.1"
                     /translation="MSQIEKYNSLDNTQQKIRISIMDMIIDKGSSVTLQEVTEYISKK
                     LNIEKEYIERTLQYFIYKNIMVVDGNSINFIYPVSALPTNHKVTLRDNRSFSAMCAID
                     AIGTSCTFNQDIKINSICSATGKEIEVIIKNEKIEYVNNPNLRVLHINLDKHLNWAAS
                     C"
     gene            24527..24676
                     /locus_tag="KOU88_001768"
     CDS             24527..24676
                     /locus_tag="KOU88_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211660.1"
                     /translation="MNFFWTKSDFDAWTNEAGLSDDEDIYCLDINEAIVESYKIFKLK
                     QKVLS"
     gene            complement(24812..25633)
                     /gene="yidA"
                     /locus_tag="KOU88_001769"
     CDS             complement(24812..25633)
                     /gene="yidA"
                     /locus_tag="KOU88_001769"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBK3211661.1"
                     /translation="MYKLIALDIDGTILNTQKRITPEVFESIQEAKRAGAKVVITTGR
                     PLPGVKELLNQLNLTDEGDYVICFNGAIIQEVKSEKIIHDVEMSLDDFDFIYNNVCKK
                     YKTKIHINTMTNLITPNETPGKYTLHEAKLNNIEVKYMQKDKIDESIKICKIMIVDEP
                     ERLEEIIQQLPKNLFNKYTIVRSAPFYLEFLGKTTNKGTALKTLCTNLNIPIENAIAV
                     GDEENDQHMIKYAGLGVAMGNARNSIKEIADYVTDTNNENGVAKVINKYILNKAI"
     gene            26126..27820
                     /locus_tag="KOU88_001770"
     CDS             26126..27820
                     /locus_tag="KOU88_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBK3211662.1"
                     /translation="MKFSEFKYERPNYNSMKKEFLSCVEDINNSRNYKEQQKNIHKIN
                     LLRNKIETLSNIASIRYSTDTFNKFYKEEKNYWDEYMPLYEELNSHFYNAIVNSKFKY
                     DLIKEFGEQFFTIVEYSLKSFSKEIISELQEENKLCSEYTRLLASAEIMFDGKIRNLS
                     GMGKFMYSKNRKTRELANKAYYNFFEENETKFDDIFDKLVKLRDKMSKKLGFEDFVEL
                     GYVRMMRSDYREYMIKNVRKQVLKYVVPMVNELYEKQAKRIGLEYLSYIDEGVEFLTG
                     NASLKGDSRYIIQNGKRMYSELSKETNEFFDFMLENELMDLETKKGKGAGGYCTYIPD
                     YKSPFIFSNFNQTADDIDVLTHEAGHAFQLYMSRWIDMPEINFPTLDSCEIHSMSMEF
                     ITWPWMDLFFKEDTDKYKFTHLSSSIKFIPYGVIVDEFQHYIYKNPNVDKSKRKEIWR
                     FLEKKYLPHRKYGDNSFLERGCWWFKQGHIFKNPFYYIDYVLAQICALQFWKKMIQDR
                     DAGWKDYINICKVGGTKSFLDIVSMGNLYSPFDDGCIESIIGDVKSWFDEINDSKL"
     regulatory      28152..28262
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            28366..28737
                     /locus_tag="KOU88_001771"
     CDS             28366..28737
                     /locus_tag="KOU88_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrdX family protein"
                     /protein_id="HBK3211663.1"
                     /translation="MIIITNNPKVKEEVQGREVLFKDTTYIGILEASRDLIHEGYELL
                     SHPLYGSVKPNETPYRTVILKKGNRLDINSLTLIEEAIITASKFQNNKKTPKWTESVQ
                     DDFRVIDYDIFYNTIQRMQYE"
     gene            28833..29780
                     /gene="trxB"
                     /locus_tag="KOU88_001772"
     CDS             28833..29780
                     /gene="trxB"
                     /locus_tag="KOU88_001772"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBK3211664.1"
                     /translation="MENVYDLVIIGSGPAGLAAGLYGARAKLKTLILEKDKTGGQIVI
                     THEIANYPGSVPNATGPSLIARMVEQCKEFGAEMLRDNIVDTELDGDIKVLKGEKAEY
                     RAKAVIIGTGATPRKIGCPGEKELTGKGVSYCATCDADFFEDFEVFVVGGGDSALEEA
                     MYLTKFARKVTIVHRRQGFRCAKSVEEKAKANPKIEFLLDTVIEEIKGDGILESVVFK
                     NKVTGETHEYFADEEDGTMGVFVFVGLDAQTDLFKGKVDMDEKGYIITDEDMRTNIPG
                     VFAAGDCRSKTLRQVVTATNDGAIASIVAEKYIDEKFGN"
     gene            29884..30201
                     /locus_tag="KOU88_001773"
     CDS             29884..30201
                     /locus_tag="KOU88_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol reductase thioredoxin"
                     /protein_id="HBK3211665.1"
                     /translation="MLDLDKATFEEEVLNAEGFVFVDFWSEGCEPCKALMPDVHKLAE
                     TYGDKIKFCKMDTTKARRLAIKQKVLGLPTMAIYKDGEKVDEVTKDDATVPNIENMIK
                     KYL"
     gene            30470..31756
                     /locus_tag="KOU88_001774"
     CDS             30470..31756
                     /locus_tag="KOU88_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBK3211666.1"
                     /translation="MRLELGKIFIKDIQFGDVTEVKDGVLFINKQEMLQEIGGDEHIK
                     SIDIELARPGESVRITPVKDVIEPRVKVEGNGGIFPGIMSKVDTVGEGKTHALKGVAV
                     VTTGKIVGFQEGIIDMTGEGAKYTPFSKLNNVVVIAEPIDGLKQYAHEKAVRMIGFKA
                     AMYLGEVARNLTPDEVSVYETKPLLESIKEYPELPKVGYVYMLQTQGLLHDTYVYGVD
                     AKQIVPTLLYPTELMDGAIVSGNCVSACDKNPSYVHINNGVVEDLYARHGKDINFVGV
                     IITNENVYLADKERSSNWTSKLCKYLGLDAVIVSQEGFGNPDTDLIMNCKKIEMQGVK
                     TVIVTDEYAGRDGGSQSLADADVRADAVVTGGNANQVVVLPKLDKVIGHLEVVDVIAG
                     GSDGSLRADGTIEVEIQAITGATNETGFGHLTAKGY"
     gene            31868..32341
                     /locus_tag="KOU88_001775"
     CDS             31868..32341
                     /locus_tag="KOU88_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011986236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:32000..32002,aa:Sec)
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase complex
                     selenoprotein A"
                     /protein_id="HBK3211667.1"
                     /translation="MSLLSNKKVLIIGDRDGIPGPAIEECVKTVEGAEVVFSSTECFV
                     UTAAGAMDLENQNRVKDAADKFGAENVVILLGAAEAEAAGLAAETVTAGDPTFAGPLA
                     GVALGLSVYHVVEEPIKSLFDESVYEDQISMMEMVLEVEEIEEEMSGIREEFCKF"
     gene            32373..33683
                     /gene="grdB"
                     /locus_tag="KOU88_001776"
     CDS             32373..33683
                     /gene="grdB"
                     /locus_tag="KOU88_001776"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:33420..33422,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBK3211668.1"
                     /translation="MGKLKAVHYINQFFAGIGGEEKADTKPHVAETLPPISLQLDKLL
                     GEDIEIVGTVVCGDSYFNENIDSASEEVLSMVKGFEPQLFIAGPAFNAGRYGVAAGTI
                     TKVVKDALNIPALTGMYVENPGADMFKKDVYVVETSDSAAGMRKALPKIAKLAVKLAN
                     GEEIGTPKDEGYIARGIRVNYFHEDRGSKRAVDMLVKKIKGEPFETEYPMPNFDRVDP
                     SKAVKDLSKCKIALVTSGGIVPKGNPDRIESSSASKYGTYSIAGVMDLTEETYETAHG
                     GYDPVYANLDADRVLPVDVLRDLEKEGVIGKLHETFYTTVGNGTSVANSKKYASEIGA
                     ALVADGVDAVILTSTUGTCTRCGATMVKEIEKTGLPVVHMCTVVPISLTVGANRIVPT
                     IAIPHPLGNPALDPTEEKALRRGLVEKALNALTTEVDGQTVFEK"
     gene            33949..35481
                     /locus_tag="KOU88_001777"
     CDS             33949..35481
                     /locus_tag="KOU88_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014520415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III family protein"
                     /protein_id="HBK3211669.1"
                     /translation="MTYPVLKGAGYVLIHTPDMIVQNGSTCTVERATNPDSEFLKEVS
                     NHIRSYEDVVNYMPNQVYIGNRRPEELRDLPMPWCEQKIEGTRNGKFGEIMPQDEFIA
                     LMQISDAFDLVKLSQEFIDEVKPKIENNYPEIAPFVGKLKGDDIEEGKELVATHIAEG
                     LYHDGKFVGYVKRAHDVDVNLNAHTMFENLVVKASGVLSAIQMLRHSKIDPAEIDYVI
                     ECSEEACGDINQRGGGNFAKSIAEIAGLQNATGSDTRGFCAAPTHALIQAAALVKAGI
                     HKNVMVVAGGASAKLGMNAKDHVKKGLPVLEDVVGGFAVLVSENDGVNPVIRTDLTGK
                     HTVGTGSSPQAVMTALITSGLDRANLKITDVDVYSVEMQNPDITKPAGAGDVPEANYK
                     MIGALAVKRGDLEKKELKDFVSNKGLPGWAPTQGHIPSGAPYIGFLIDDLTTGNRNRA
                     MIVGKGSLFLGRMTNLFDGVSFITERNTGVTEETSGISKDEIKKIIAESMKKLALDML
                     EE"
     gene            35492..36637
                     /locus_tag="KOU88_001778"
     CDS             35492..36637
                     /locus_tag="KOU88_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine reductase"
                     /protein_id="HBK3211670.1"
                     /translation="MSKKVIADVFLEVANAIESGEFGKKVKIGVTTLGSEHGVENMVN
                     GAQLAKSNLFDILLIGPKVETDLEVVEVNDEKEMHAKMEELLDSGYIDACVTMHYNFP
                     IGVSTVGRVITPAKGKEMILATTTGTSATNRIEAMVRNAIYGIATAKSMGNKCPKVGI
                     LNVDGARQVEKCLKELKDNGYDMEFADSIRADGGCVMRGNDLLVGAPDVMVTDTLSGN
                     IFMKVFSSYTTGGDYEAQGFGYGPGVGEDYDRKVLIVSRASGSPVVANALKYAYDVVK
                     GDISNVARNEFAKVKKAKFDDIISSLTKKEVKAEKVEVKMPDKEIVTRQIAGVDIMDL
                     EDAVSELWKNGIYAESGMGCTGPIVLVNEAKGDLAVETLVKAGYTAK"
     gene            36947..38026
                     /locus_tag="KOU88_001779"
     CDS             36947..38026
                     /locus_tag="KOU88_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK3211671.1"
                     /translation="MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICK
                     DGNFLVTDSRYMELAEKVCKDFEIINWHNFDRSVAKAVKSVCDKVGIKKLGFERTNIV
                     FDKYEELKNLIEKDNGELIPTENIVETLRYAKDKDEIKNTRKACEIADKALEELIPHI
                     KAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID
                     YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRK
                     VVKKYEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIE
                     DTVLITKNGPERLTKFPKDLMILDK"
     gene            38138..38737
                     /locus_tag="KOU88_001780"
     CDS             38138..38737
                     /locus_tag="KOU88_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211672.1"
                     /translation="MYKKHKFIKNIKKAWYKIKLIDRCLIIVMAILMFQSIYNLFVNE
                     VNSQDTTTIDVVVRTTSAAIFGYFLSANFIKRPLRKYTNTDVSSNLFIDNNLSPKGQE
                     SSQNNIMNVKNTIGFTSEADNYEKKIPINNNEGFEEGETSELQIIIATVICIVALTVL
                     FVVRNFTTTTSASLGTISQMRDFVSGCVGFLLGCPSKPD"
     gene            complement(38924..39796)
                     /locus_tag="KOU88_001781"
     CDS             complement(38924..39796)
                     /locus_tag="KOU88_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3211673.1"
                     /translation="MNINYLYYFQTVCKYKNMTKAAESIHISQPSITLAIKELEKELG
                     FELFYRIGNKIELTPEGKIFLDKSKHFIKQFEDFQCDALDLGKKRKASLKIGIPTVLG
                     TFLLSKILPRFNVIYPDIELKIFEVPTFVGAKMIEESTLDFCIGIIDSDIYDDIDSKT
                     IYKTELYLVTNPKNELAKHPIISNYMLKNVPFVILSEGSYHYKIITKRLEKAKPNIIL
                     HSNQLSTIRYLLENDLASTILYKEIFQNTENLCSIPLERAITANIGVLWRRNQYISHS
                     MKLFIDYMASIHIN"
     gene            40213..41616
                     /locus_tag="KOU88_001782"
     CDS             40213..41616
                     /locus_tag="KOU88_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211674.1"
                     /translation="MKGSDLVKFELMDFLMNPFVLMFAAVITGILFGKIKFGKFNFGV
                     SGALFTGLFIGWLAYSLGNLIIAKGETAAGYKAATVMMGNGIISSDFFDFFLIIFVAA
                     VGLLAAKDMKAVLKKYGARFVILGVLITFIGGSMTYAMTLLSSDKGSSAYEVSGVYTG
                     ALTSSPGLAAALETAGKHAEDVSKEFEKASIKDKKEILKVVDPEGKLDVNTTTSLTQE
                     QIDKYIAYAEAGVGIGHAVAYPFGVLIVILGVNFLPKLFRMDLKEERRKYEKEMKEAR
                     DSVSGKTIPEVPFNIITFFLTCLAGYLVGGIHVFMGPLGYFTLGATGGSLIVSLVLGY
                     IGKIGVVNFRMEEKVLNILKQIGLVFFLAIVGLRYGGKVVDSIMTSGMHLALVAIAVG
                     VTAMMIGFLVGKYVFKLNWILLSGAVCGGMTSTPGLGAAVDALDSDDPAAGYGATYPF
                     ALLTKVILVIVLHKLPM"
     gene            41643..43187
                     /locus_tag="KOU88_001783"
     CDS             41643..43187
                     /locus_tag="KOU88_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBK3211675.1"
                     /translation="MNNEGAFEELSGRLRNKELCDLIMNADEAAKIIEDGMVIGVSGF
                     TPSGYPKAVPLAVSERAKSGEKIKLTVYSGASLGPEVDGAWSEAGIIERRLPYQTNSI
                     LRNNINKGVVDYIDMHLSHSTQFLNYGTIPKVDVAIVEALAITEEGNIIPTSGIGNSP
                     SFIKSADKVIVEINLAKPMEMEGMADIYITENPPNRKPIEINHPKDRIGTTYIPCGLD
                     KIAGVVITNMQDKTRPLGVVDEASKKISNNIIAFLREEVKAGRLSKNLLPLQSGVGSV
                     ANAVLYGLCESEFENLTCYTEVVQDSMLDLIRMGKVTMASTTSVSPSPEGLIKFEKDI
                     DFFKDKIILRPQEISNNPEIARRIGVIAMNTAIEVDIYGNVNSTHIMGSKMMNGIGGS
                     GDFARNGAITIFSTESIAKNGDISSIVPMVSHVDHTEHDVMVIVTEQGYADLRGLAPR
                     ERAIKIIENCAHPDYKEQLRDYLNRACKSGAKQTPHILDEALSWHSKFMSTGTMKKAE
                     TFKSAL"
     gene            43218..44609
                     /locus_tag="KOU88_001784"
     CDS             43218..44609
                     /locus_tag="KOU88_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HBK3211676.1"
                     /translation="MEKAVENFEDLSKEYINGYIERARKAQREFECYTQEQVDKIVKI
                     VGKVVYYNAEYLAKLAVEETGMGVYEDKVAKNKSKAKVIYNNLKDKKSVGIIDIDRET
                     GITKVAKPVGVVAAITPCTNPIVTPMSNAMFALKGRNAIIITPHHKAIGCSTKTVEMI
                     NEELEKIGAPENLIQILDQQSRENTRNLISSADVVIATGGMGMVKAAYSSGKPALGVG
                     AGNVQCIIDRDVDIKEAVPKIIAGRIFDNGIICSGEQSVIVAEEMFDKIMDEFKNNKG
                     FIVRDKVQKEAFRNAMFVNKSMNKDAVGQSVHTIAKIAGVEIPEDTKIIVIEADGPGE
                     EDIIAKEKMCPVISAYKYKSFEEGVAIAKANLNVEGKGHSVSIHSNTVKNIEYAGENI
                     EVSRFVINQCCATSAGGSFFNGLAPTNTLGCGSWGNNSISENLDYKHLINISRIAYYM
                     PENEVPTDEELWG"
     gene            44802..46298
                     /gene="abfD"
                     /locus_tag="KOU88_001785"
     CDS             44802..46298
                     /gene="abfD"
                     /locus_tag="KOU88_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyryl-CoA
                     dehydratase/vinylacetyl-CoA-Delta-isomerase"
                     /protein_id="HBK3211677.1"
                     /translation="MALMTGAQYIESLRKLNTKVYMFGEEVKNWVDHPMIRPSINCVA
                     ATYDLAHDPEYADLMTVTSNITGEKINRFGHLHQSVDDLIKKVKMQRLCGQKTASCFQ
                     RCVGMDAFNAVYSTTFECDKAHGTNYHDNFVKYLTYIQENDLVVDGAMTDPKGDRSLS
                     PSAQPDPDMFLHIVERREDGIIVRGAKAHQTGSINSHEHLIMPTISMTEADKDYAVSF
                     AVPSDAEGVFMIYGRQSCDTRKLEEGADVDLGNKEFGGQEALVVFDNVFVPNDRIFLC
                     GEWDFSGMLVERFAGYHRQSYGGCKVGVGDVIIGAAALAADYNGANKASHIKDKLIEM
                     THLNESLYCCGIACSSEGHKTEAGNYQIDLLLANVCKQNVTRFPYEIVRLAEDIAGGL
                     MVTMPSEKDFKSDLKVGTSGMTIGEVCNKYFKASSVASTEERMRILRFLENICLGSSA
                     VGYRTESMHGAGSPQAQRIMISRQGNINQKKELAKKIAGIKKEEALNL"
     gene            46433..46708
                     /locus_tag="KOU88_001786"
     CDS             46433..46708
                     /locus_tag="KOU88_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211678.1"
                     /translation="MTCGVRFCGGCNPRYERGKALTIIKEHFNGRVDFSIAQENIEYD
                     LLLIIGGCATLCASYQQYKVKNECVKMWDFSHIERVINVIESAICET"
     gene            46732..48039
                     /locus_tag="KOU88_001787"
     CDS             46732..48039
                     /locus_tag="KOU88_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA hydrolase/transferase family protein"
                     /protein_id="HBK3211679.1"
                     /translation="MSWQELYQSKLCSATEAVKQIKNGDTVVFAHCVGEPPALVEAMI
                     ENAEQYKDVEIKHMVSLGSGGYTAKGMEAHFRVNPMFVSGNVRKAIENGDGDFTPAFF
                     HEVPKLLREKRLKCDVVLAQVTPPDEHGYCSLGTSVDYTYEAIKTARTVIVQVNDQFP
                     RTYGEVVHVSEFDYIVEKSQPLFELQPAKIGEVEEAIGKNCASLIEDGSTLQLGIGGI
                     PDAVMLFLTDKKDLGIHSEMISDGTLALYEKGVINGKYKNFDKEKMTVTFLMGTKKLY
                     DFANNNPAVEVKPVDYVNHPAIIMKQHKMVSINSAIQVDLMGQVVAEAMGLRQFSGVG
                     GQVDFIRGVSMGEDGKAIIAMPSITTKKDGTVISKIVSIVDEGAPITTSRNDVDYIVT
                     EYGIAELKGKSLRERARNLINIAHPSVREHLAVEFEKRFKEKY"
     gene            48059..49177
                     /locus_tag="KOU88_001788"
     CDS             48059..49177
                     /locus_tag="KOU88_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybutyrate dehydrogenase"
                     /protein_id="HBK3211680.1"
                     /translation="MEALRVVPKIFYFDTFKEFNEEFKIGKNDLVITNEFIYEPYMKP
                     LGIDTNLIFQEKFGTGEPSDEMIDSMTKEMKKYNFDRIIAFGGGTIVDICKILALDVP
                     EKSIDLFEGEVSPKKVKELVVVPTTCGTGSEVTNVAIAELKSKHTKKGLAVEETYADY
                     AVLIPETVKGLPYKFFVTSSVDALIHAIESYLSPKASPFTEMYSLQAIKMIMDGYKKI
                     VDKGEEERFNHLRDFVLASNYAGIAFGNAGCAAVHALSYSIGGAFHVAHGEANYQFFT
                     EVFKMYSRKKPNGKIIKCTKILADALECDPNCDVYGELEKFLNKLIAKKALREYGMVE
                     SQIDEFTDSTIANQQRLLANNYVELSREEIREIFANLY"
     gene            49464..50384
                     /locus_tag="KOU88_001789"
     CDS             49464..50384
                     /locus_tag="KOU88_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBK3211681.1"
                     /translation="MYKSENFSKKSVLINSFLSKFLKIIGWGLVSLFTLSALVLSTIS
                     IIIGWAVILHIQVCAVFLLIGGVCIFKGKRLGDQISRYKKYCTIINNRNIIPVELIAE
                     NTSKSLNFIIKDVQKMIDKNYFINTYIDKRNNQIVLTNEDFVPPRYEDVAYEVKEEEK
                     TDESNEVDTIINKGMNYLTQIKEANKNIKSESMGDKIVQVEDVTSKIFDVVKHDPSKL
                     TQIQKFMDYYLPTTLKLLNSYHTLEEQGIDRENITTTMESIENTMNTIVVAFENQLDY
                     LFEDEAIDISTDITVLENMLVQEGLTSGKF"
     gene            50499..51656
                     /locus_tag="KOU88_001790"
     CDS             50499..51656
                     /locus_tag="KOU88_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBK3211682.1"
                     /translation="MNNLDDIPVMPTLTLDPFGEESNTNDIDNSDLLMKKDEKDPEEE
                     KLSESERKMVKEFAEKIDITNTNMILQYGAGAQKKVASFSETALKSVKTRDLGEVGDM
                     LTNLVTDLKAFSADEKEQSGFLGIFKKANNKISNLKTKYDSAEVNVDKVSKELQKHQV
                     KILKDIAMLDKMYELNLAYSKELTMYIIAGKQKLKDMKEYEMPKLREKARLSGSTEDA
                     QSVNDMVSLCDRFEKKIHDLELTRMVSLQMAPQIRLVQNSNNLMAEKIQSTIVNTIPL
                     WKNQIVLALGISHLNQAMKAQREVSNMTNELLLKNAETLKMGTIETAKESERGIVDID
                     TIKKTNQSLISTIDEVVKIQHDGRIKRQEAEVELSKIENELKSKLLEFTVK"
     gene            complement(51741..53240)
                     /locus_tag="KOU88_001791"
     CDS             complement(51741..53240)
                     /locus_tag="KOU88_001791"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBK3211683.1"
                     /translation="MAFYFDTPSHTFSEYLLVPGFSSTDCIPANVSLKTPVTKFKKGE
                     EADIYMNIPLTSAIMQSVSDDKMAIALAKEGGISFIYGSQTIENEAAMVARVKSHKAG
                     FVVSDSNIKPDNTLKDILDLKEKTGHSTVAVTEDGTSTGKLLGIVASRDYRISRMDLD
                     TKVSEFMTPMSSIVYANKDVTLKEANNIIWDHKLNSLPVLDDNGNLMYMVFRKDYSSH
                     KENPLELLDSSKRYVVGAGINTRDFAERVPALVEAGADVLCIDSSEGFSEWQKITLDF
                     IREKYGDTVKVGAGNVVDREGFLYLAEAGADFVKVGIGGGSICITREQKGIGRGQATS
                     IIEVAQARDEYFEKTGIYIPICSDGGIVYDHHITLALAMGADFIMLGRYFSRFDESPT
                     NKVNINGSYMKEYWGEGSARARNWQRYDLGGDKKLSFEEGVDSYVPYAGSLKDNVTLS
                     LSKVRSTMCNCGALSIPELQKNAKLTLVSSTSIVEGGAHDVMLKDNRNL"
     gene            53836..55260
                     /locus_tag="KOU88_001792"
     CDS             53836..55260
                     /locus_tag="KOU88_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBK3211684.1"
                     /translation="MSSSNQSTIKTSIQRVGKFLSGMVMPNIGAFIAWGLITALFIPT
                     GWMPNEKLSTIGDPMIKYLLPLLIAYTGGKAIAGQRGGVIGAAAAMGVIVGADIPMFI
                     GAMIMGPFAGWVIKKFDKFVDGKIPTGFEMLVNNFSIGIIGMLLAILGFYAIGPAIVA
                     GTALIESGVQFIVSKSLLPLVSVFIEPGKVLFLNNAINHGILGPIGIAEAKEAGKSIM
                     FLLESNPGPGLGVLLAYWMFSRGSVKQSAPGAVIIHFFGGIHEIYFPYILMNPVLILA
                     TMAGGAAGILTFSILGAGLVAAPSPGSIFALMALAPKGGLLPVLAGVAVATVVSFLVA
                     APFVKRASANQSEEDSTSLEEAKAKMSDMKSASKNSEKNIEEKQLEVNEIKKIVFACD
                     AGMGSSAMGASRFKNRIKNLDLNIEITNSSVDNLPDDTQIVVTHNTLVERVAKNNSSV
                     EIVSINNFLNDPNLDTLFKRLESK"
     gene            55295..57424
                     /locus_tag="KOU88_001793"
     CDS             55295..57424
                     /locus_tag="KOU88_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK3211685.1"
                     /translation="MKKKKITSRQKKIILMIVENSKKNIPITISEIAGTLELSSRTVL
                     RDMSGIEKWFDENDFNFVKKPGVGLILEENIENQNFIIELLEEEKIEKEYSKEERNLI
                     ILSKLLVSNEPVKSYYFAKILKVSEGVLNNDFALASKWLERFDIELVRKPGLGVYLKG
                     QEKSFREAYVNLIYDSFNEKEILDMVRNISENIQTDKAIEILSENRLLNLMDRCIIRK
                     VEATLTKKLSDLDVNLADSAYIGLVVHISLALQRIKNGENITMDKEFLKELSITEEFK
                     LAKEIVKGMETDFNMDIPVDEVGYITMHIRGAKQRSSSNHKALNLDDIEIMEITNKMI
                     DLAEDEFKISLKNDERLFKDLANHLGPSINRLNMGLEIRNPLLDEIKSKYSYAYDGVE
                     KISRIIKDKLNINSIPESEIGYIAMHFASAIEKNLMMNTNINIVVACPTGIGTSRFLS
                     TKIENKFPNLNILETISAINIDEEYLKEKDVDLIVSTVELNTSLNYICVGPFMSLDDE
                     QIIKEKIKSIAQNKLINLNAKNDTKSKNKVYEQITESMNIGKDILQFLEEIRFEKFES
                     KDLSELIEDSSKIFAKSSEDIISIKESLKERLKISIPYIEESKILLLHCMSERIDIMK
                     LSIIKLENRIVLDSNEEIDNVVFMLLPKNSPSYQRQIMSEISGSLIDNIIFTNKINKF
                     SIEEMALEVKDIVFNFYTNRLKAFIDK"
     gene            57454..57876
                     /locus_tag="KOU88_001794"
     CDS             57454..57876
                     /locus_tag="KOU88_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3211686.1"
                     /translation="MSKVLNENNIFLGLDSVSKEEAITLAGRKLVENGYVKEEYIPAM
                     LEREKVMTTYMGMGVAIPHGVNEAKKEILSSGIVILQFPNGIDFDGEKAYLLIGIAGV
                     GDEHLEILSNIAVVLDDDLTERLKNSNDKQAFMEAFAN"
     gene            57895..59046
                     /locus_tag="KOU88_001795"
     CDS             57895..59046
                     /locus_tag="KOU88_001795"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBK3211687.1"
                     /translation="MKKAIQFGAGNIGRGFIGGLLVKSGYHVVFADVNEDILNSINKD
                     KKYTIHIRDVECIDEVIDNISAVSSIKEEIIDEIVQAEIITTAVGPLVLTKIASTIAK
                     GIKARKEKGLTSNLNIIACENAIYASSSLKEEVLKYLNKEEVEYLEMYVGFPNCSVDR
                     IVPPGKNENPLDVTVENFYEWNVEKQGFKGEIPTIVGMNLADNLMAYIERKLFTLNTG
                     HAITAYIGYLKGYKTIEESIKDKFICDIVKSAMVESGEGLIKKYNFDSEVHYKYIDKI
                     LNRFKNPYLNDDVLRVGREPLRKLSDKDRLIKPLMTAKSYGLSVDNLILGIGAALHYN
                     NSEDTQSVELQELIKSIGVKKAVAKIANISNDEELLNNIEKSYIFMKNL"
     regulatory      59152..59253
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            59436..60008
                     /locus_tag="KOU88_001796"
     CDS             59436..60008
                     /locus_tag="KOU88_001796"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBK3211688.1"
                     /translation="MKALQEKILREGSVSGNDILKVDSFLNHQIDVAFLNEIGREFKE
                     RFKGEKVDKIFTIEASGIAIASIVSQYFDNAPVVFAKKSESKNLDKDVYETNVYSFTK
                     AREYSVKVSKKYINKGENILIVDDFLANGRAALGLKDLIEQAEANLVGVGIVIEKGFQ
                     AGGALLKANDVRLESLAVVESIDNGTVKFR"
     gene            60072..60722
                     /gene="fsa"
                     /locus_tag="KOU88_001797"
     CDS             60072..60722
                     /gene="fsa"
                     /locus_tag="KOU88_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBK3211689.1"
                     /translation="MRFFIDTANIEEIKEANDLGVICGVTTNPSLIAKEGRDFIEVVK
                     EISEIVDGPISAEVISLEHKGMIEEAEKLSKIHKNIVIKIPMTAEGLKAVKVLSSKGI
                     KTNVTLIFSAGQALLAARAGATYVSPFVGRLDDISQNGLDLIEEIVDIFSVNSIEAQI
                     IVASVRNPIHVLQAARMGADIATVPLKVINQMIKHPLTDKGIDSFMKDWEGASLKL"
     gene            60874..63798
                     /locus_tag="KOU88_001798"
     CDS             60874..63798
                     /locus_tag="KOU88_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3211690.1"
                     /translation="MDKILREIQREDKKNPYTDQELAEMLNVARSEVISVRKKNNILD
                     SRERRKKILIKDISKIVSENPQMSERKITEILIENGYNISRSAVSKLLKEENLNQSKI
                     GIKDKDPASSGKYVKVSKVVEEDGFEELIGIKGSLKEKVNLAKSAIMYPPNGLHTIIY
                     GETGVGKSELATCMYKYAIKNNIKEENSPFIVFNCADYAENPNLLIAQLFGVVKGAYT
                     GADANREGLVEQANNGILFLDEIHRLPAAGQEILFSLIDRGEFRRLGESSSNRKANVL
                     IISATTENPDSNLLQTFRRRIPMVINLPNMSERPKSERYEIIIKFFEREAKRVNKNFI
                     ITKEVMCALMNYKCTGNIGQLKSDIQVTCARAFSKSIFSSDKVIIDLDSLRDYIKSGY
                     YDCNCKNEKYSEFSVEDIYIDISELVSGKNRILSDNEISEIYNYAEKELKVLESKCFS
                     EEELKNAFIEKLDKKFNAIKNNKNLSDRRSRIDWGGQLKESTLEIMDKVIVFIKEQFK
                     HVNQGLYLALAIHIEHAIGRIKDGKTIINPSLDKIKASMPMEYELSRYIMGIVEDLTQ
                     VTFPEDELGYLAYYINKFCYNEESIKDKVKVVIVTHGKVGIEMSKVVNHILGIECTLG
                     IEIALTDSPSEGIEHVLEELQKIEARKGILVLIDMGSLVILGDEVEKRLGIRCKTVNR
                     VDTLLAMEAGKLATIEGKSLDGIIADLKKNKNYAMINTNKFSYRKNEYGKKNVIITLC
                     LSGLGTALNLKEHIEKQIKEYDTLIEVKPVAFLNNNLEEELNDIEAEYNIIAICGTID
                     IDYKNVPFISYNEVLGKNGINKVLEHLNSKQPALNIENQLNNLIHEDLILYNFEGISK
                     EYIIDTLVSKLEEGGYVDSKYILSVYKREAMGSVVMASKVAVPHGLPENVIKPAIAIA
                     RLNKPIVWDNKFMVDLVVLLALKENNKKEIRSLFSKINDQHTLEVLLNTEDKNEIKEL
                     LS"
     gene            64387..64845
                     /locus_tag="KOU88_001799"
     CDS             64387..64845
                     /locus_tag="KOU88_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3211691.1"
                     /translation="MEFINFVSDKVIDLKMDCKTKEDFFKEIHNKVFDLGFVKEEFGE
                     KILARENVFPTGLNLGDYGVAIPHTDAEYIKEQFISVCTFNEPVVFSSMEDQDEKVPV
                     NLAFVLGLNQPHSQLSVLTELMAIMQNKELVDKLMSSTDKEEVLKTLKSL"
     gene            64906..65181
                     /locus_tag="KOU88_001800"
     CDS             64906..65181
                     /locus_tag="KOU88_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3211692.1"
                     /translation="MKKILVACGAGIATSTVVCDKVERLVKENNIQAEVIQCKIAECA
                     TKQEGADLIVSTTILPTTYNIPAIKATAYITGVNTAALDKKILDALK"
     gene            65240..66514
                     /locus_tag="KOU88_001801"
     CDS             65240..66514
                     /locus_tag="KOU88_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012951111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBK3211693.1"
                     /translation="MDKLLAVVQYILNMGPTVILPITIVVLGMIFRIKFTKALKSGLT
                     IGIGFVGINLVVNLLTSTLGPAAQGMVERFGLNLTVIDVGWPTTASATWASPVAPILI
                     PVCLLVNLLLLYFNKTKILNVDIWNYWHFIVAGAVGYIVTGSYVWAIFCAILMELLVL
                     FIAEKTAKNVQEFYDLEGIALPTGSTASFAPLGYLVGKFVEKIPGINKIQADPDSIQK
                     RFGIFGEPMMMGIILGIILGALAGYDVAGIFNVGISMGAVMLLMPRMVRILMEGLIPI
                     SESIRDFLQAKYGDRELYIGLDAAVATGHPAVISTALILVPITLFLAVILPGNKVLPF
                     GDLATIPFYMAFIVCFRKGNIVQSVITGTIVIAISLYMATNFADVHTQLLQQANMMPE
                     GTTMVTSIDTGGNLLKWGILKLSQLVSSFGIF"
     gene            66644..67696
                     /locus_tag="KOU88_001802"
     CDS             66644..67696
                     /locus_tag="KOU88_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBK3211694.1"
                     /translation="MKAAVLHGTNDMRFEDIEIKPCESDEVKIKVMAAGICGSDPPRV
                     LKHWKYPVPAIPGHEFSGVIAEVGKDVKNVKVGDRVVAIPFIPCNECEYCKRGLFSLC
                     DNHGMLGAKSFGAFAEYVNIKATNVLPIGDMNFEDAAMIEPLAVAMHGVLNIGVQVGD
                     TVAVMGSGTMGQLVIQGLKIAGAGTIIAVDISDNKLRESKELGADIIINAKDTNPVEK
                     IKELTGGKGVDIALECAGSKITQEQCLLITKKKSKIGFLGIAYSDITLSEEAFENIFR
                     KELELKGFWNSYSAPFPGQEWTKGINLVNEGKIKLKEMVSHRFSLEDTYKAFEMIRDR
                     KEEFNKILILPQGVEK"
     gene            67696..68727
                     /locus_tag="KOU88_001803"
     CDS             67696..68727
                     /locus_tag="KOU88_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBK3211695.1"
                     /translation="MKAVVKTKPGYDNVEVLEVEEPKATGDKVKIKVEYSGICGSDIH
                     SFKGEYANIKAPVTLGHEFSGIVVEVGEDVKNIKVGDRVTSETTFATCEKCIYCETKD
                     YNLCPTRKGIGTQVNGSFAEYVLSREESIHVLPENVSLLSAALTEPLACCVHAALEKT
                     TIESSDTVLIIGPGPIGLLLAQVVKSQGTTVIMSGVTKDKERLEIAKNLGVDRTVNVM
                     EESLADVVNEMTDGNGVNKGFDCSGFMPAVNEALRLLRKKGTFVQVGIFAKKLNEMDQ
                     EAIIQRELQYIGSRSQKPSSWITALDLMANGKVNTEALVTRTVGLDEFKEGITALMNG
                     EEIKVAVKS"
     gene            68819..69631
                     /locus_tag="KOU88_001804"
     CDS             68819..69631
                     /locus_tag="KOU88_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBK3211696.1"
                     /translation="MSTLRDHSNNIRKNIIKMVAEAKSGHPGGSLSIADMLTVLYFDK
                     MNVCAENPKMADRDRFVLSKGHAAPALYATLAEKGFFPEEELITLRKFGSKLQGHPDM
                     KKVAGIDMSTGSLGQGLSAANGMALAGKLDNKDYTVYTILGDGEIQEGQIWEAAMTAS
                     HYKLDNLIAFVDLNGLQIDGSNEEVMNVNPVDDKFKSFGWNVIVINGHSFEEIGNAVD
                     EAKKVTGKPTVIIAKTVKGKGVSFMENNAAWHGTAPNAEQAEQALKDLEGGL"
     gene            69634..70554
                     /locus_tag="KOU88_001805"
     CDS             69634..70554
                     /locus_tag="KOU88_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HBK3211697.1"
                     /translation="MGIATREAYGQVLKELAENKDIVVLDADLGKATKSISFKEVAPD
                     RFFDMGIAEGDMIGTAAGLATCGKIPFASTFAIFAAGRGYEQIRNSVAYPNLNVKIAA
                     THAGVTVGEDGGSHQAIEDISLMRGIPNMVVLNPADALEARQAILASIDYNGPVYIRL
                     GRAATPDVNSENYKFEIGKGTVLREGSDITVIATGIMVAKALEAAEELAKEGINVEVV
                     NISTIKPLDEALIKETAKKTGKVVTAEEHSIIGGLGSAVCEALAETKDVVVRRIGVKD
                     VFGQSGTPADLLKHYGLTTEDIVKNIKELL"
     gene            70729..71175
                     /gene="rpiB"
                     /locus_tag="KOU88_001806"
     CDS             70729..71175
                     /gene="rpiB"
                     /locus_tag="KOU88_001806"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase B"
                     /protein_id="HBK3211698.1"
                     /translation="MKISIGCDHGGYELKEYIKENLINKGIEVEDVGTNSKESVDFPI
                     YAKKVSQNVQSKKSDLGILCCGTGIGMSIAANKFKGIRAAVVSDCFSAKATREHNNTN
                     VLCLGERVIGKGLAMRIVEEWLNSSYNGERHARRLQMIDDIEKENL"
     gene            71205..71870
                     /locus_tag="KOU88_001807"
     CDS             71205..71870
                     /locus_tag="KOU88_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBK3211699.1"
                     /translation="MSIICASIMCADQMKLKEELEALEEAGVKLLHCDVMDGIFVKNL
                     AMGPELLKSISENTTIPLDIHLATETPDKYIDMMSYIKPKYISFHVESSTNVKADIQK
                     LRNYGIGPVLAISPQTSVDKIEEYISLVEGILVMTVNPGFAGQKFNLSVLDKLDKLTE
                     ILKDYDNPPFIEVDGNINKDTIKLMNGKKVDIYVVGTSALFNDKPPISYKDKIEELKE
                     SIK"
     gene            71980..73482
                     /locus_tag="KOU88_001808"
     CDS             71980..73482
                     /locus_tag="KOU88_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBK3211700.1"
                     /translation="MGDLYKLQNGTDIRGIAYENDSKEVNLTVEEVKKIAKAFHIWLK
                     EKTKKDKVTVAIGTDSRITGSQFRSTVIETLTNDDCNVIDCEIATTPAMFMTTIMDGY
                     NSDGAIMITASHLPYYYNGLKFFTESGGLEKTDIKEMLDIAVKNDSVDYEEVNKKGEV
                     IVKNLIEDYSNLLIDKIRKGVNSSKNYEKPFSGLKILVDAGNGAGGFFAEKVLHILGA
                     DTTGSQFLNPDGMFPNHIPNPENKEAMESICKAVLDNKSDLGIIFDTDVDRAAIVGKN
                     GKPINKNALIAVISSIVLEEHPKTAIVTDSITSEGLAKFINELQGRHHRFKRGYKNVI
                     NEAIRLNSEGEECHLAIETSGHAALKENYFLDDGAYLIAKILIKVAKLSLEGKTIEEL
                     IENLEEAQEEKEVRIGINKEDFRPYAEDILKDLDSHVKSIDGWSVAPNNFEGIRVNCD
                     ESNGDGWFLLRISLHEPLLALNIESNKIGGAEQIYSKLKLFLEKYDLKGL"
     gene            complement(73794..>74845)
                     /locus_tag="KOU88_001809"
     CDS             complement(73794..>74845)
                     /locus_tag="KOU88_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK3211701.1"
                     /translation="NLLSMYNKKTINKKLAIVFLISIVVQAIIQYLVLIFFMYIYYAE
                     AIAIVILFTLVNTVFHFYIYNFLSVKFNYINNISKNIKNIENGNLKYKLEVIGDDEIS
                     TLAKSINNITGGLETAVDANIKNERMKAELITNVSHDLKTPLTSILSYVDMLKNNDFD
                     RETINDYINILDKKSQRLKLLIDDIFEASKLSSGDVEFNITKTDIRELLIQSIVEFED
                     KIQNSSLDFIIETPEYAVFTMIDGKKTWRVFENLICNILKYSMPNTRVYIDMFIKEEN
                     IILTFKNISNDKLNLKPEELIERFRRGDISRKTDGSGLGLSIAQNIIELENAHMEIII
                     DADLFKVMLTFRRVN"
BASE COUNT        29514 a         8127 c        13754 g        23450 t
ORIGIN      
        1 attgctctta aaaatataac tataataata aaaaaatatc taaaaaaaga catgcttatg
       61 ataaggtatg gtggagaaga atttctgata ttatctgtat gtaaagatta taaaaaaagt
      121 aaaatatttg gaagaaaatt atgtaggatt gtaaagaaat ttttaaacaa taatttgaca
      181 gttagtattg gcattgatac atgtaaaaat agtagtatag atataaaaga aataattgaa
      241 aatgctgata aagctttata taaagcaaag gaaagtggta gaaatagatg tttgcattat
      301 catgatttta agaattttta actgttgaaa taggattggt gatttacttg aaaaggagtt
      361 taatagaaga tttaaagaga aatataaaca agatagaata cgatatgttg actaaattct
      421 atctaaattt gacagattta aactacatct tggattatca caaagacctt ttaaatacaa
      481 aattagaaga taatagtaga gtctatactt tatatttaat tagtcttata aactatataa
      541 aaaaagatag agaagcatca tacaactatt tgatagagtc attaaagtat attaaaaaat
      601 tgtcattaaa agatgattca gatataatat ctaaaattta tatttatctt actttatcag
      661 ctatttctat aagaaaatat gataaggtaa ataattttta tttctcagca aaaaaattat
      721 aagacaaaat catttaaatg agttgttggt attgttaaat atgagtttat gtgtagaaat
      781 aagtgcttta tatcagacca aaacggatgt aatagcttta gtagaagaag tgtctttttt
      841 taaaacttta aaaaataaag ctcttgtaag tagggcaaat tatatatttg ggagagttta
      901 tctatattta tttaataact ttataaaaag tatggaatac ttaattgaat gtctaaaatt
      961 ggctcaagaa aataatttat actctataga ggctttttgt aaatgtataa taagtttgtg
     1021 ttatttagag agtggaaata atgtagaagc tataaaatac ataaataatg tattagatgt
     1081 tgcacacagt aataactcaa tatcagtaac tgaaagagtg tctataaaga tagaccttat
     1141 atgggcatat ttaaaagaag atatgaataa agaagcagaa gttattttat taaagactat
     1201 aaaattaatg aaagttgttg aaggtgtata taaggattat ttatattcat ttatattttt
     1261 atattcagct gaaattgagt taaagaaaga taattgtagt tttgaaaagg taaacaccta
     1321 tttaatttta tcaaaaaata tatataaaag ttttggagat gtttttatat ataattctaa
     1381 actagattac atatataagt tgtatggaga tttatatata aaatttggta atatagatga
     1441 aggtataagt tgttatataa aaggtttaaa tttagttaaa aagagttcat tgaatcttag
     1501 aaaaatatct atattttatg ggctaatagc aaatggatat gagctaaaaa aagattttaa
     1561 actggcaata gaatattata aaagtatgga ttggtattct gataggtggg aaaaaaataa
     1621 ttcctataaa acatctcaag caattcacaa acaatatgaa ctcagacaaa aacaagagag
     1681 tttaagatta ctagtggatg ataataagaa attagaaaat gatattttaa aagatggact
     1741 tactaaacta tataatagaa gatatttgga acagcagttg gatttattta atggaaccag
     1801 agacaaaaat atggtcgcaa tactggtcga tatagattgt tttaaaagtt ataatgataa
     1861 ttatggtcat ctagcaggag ataaagttat agttaaggta actgatatta taagaagtgt
     1921 atttatagat attaccgaac acataatcag atatggggga gaagaaattt taatattagt
     1981 agattctata gaatcaatcg gtgttgaaga gattgataat atagaattat atattaaaag
     2041 agttttcaaa cttcttgaat ttgagggtat tgaacatata tattctaaaa taaaaaacta
     2101 tataactata agtgctggag taagtataaa aaggtgtcgt agtagaaaag atgttgaaat
     2161 attaattgaa gatgcagata agaacctata taaatcaaaa aaagcaggta gaaatcaata
     2221 cattataatt taaaattgag gtgattttgt tgcgaaaaaa aataggaatt atagcctctg
     2281 atattgaatt aaaagaaaga atagaagaat tatatagaga agatgtagaa aatggaacta
     2341 taataatcga catacttaac ctagacttaa tggaaaatca aggtcgtata cttgttgaaa
     2401 aaggtgccca agctataatt ggtagaggtg gaggttatag cttagtaata gatacagtaa
     2461 atgtacctgt tataccaatg aatatgaagt caactgacct tttaagagca atagaaatag
     2521 caaagaaata ttctaaaaaa gtagtattga ttcttggaga caatgaagtt tcttttgact
     2581 atgttggctg gagaaatgtc ataagtactg aaataactga agaatggttt gaatctaagt
     2641 atgagataag aagtaaagtt gtaaaatata tagaccaaaa agatgaagtt gtaatcgtag
     2701 gaggaggttt ggcatgttct tttgcaaggc aatatggaat tgatagtgta tttgcaactg
     2761 ctagtgatga atctataaga gaagctgtag aatattgtaa aaaattatta gatacattag
     2821 gtgaagaaaa gtttaataat gaagtgttac gaaatatact tgatggtata aaagatggag
     2881 taattgctat agatagtaat ggcagtataa ttttgtacaa tgaaagtgca aaaaacatgc
     2941 ttaaagtaga gagaaaatgt gcacttaata aatacatctt agatgtattt cctaaaatgg
     3001 agtggatgtt agattgttta catgaaaaag aggacgtaga agatagaaag ataagaaata
     3061 taaataatct aattgttaat actaggacaa cattgataaa agttgataat agtacttatg
     3121 gagttttagg aataatacaa gatataacca agctacaaaa cttagaaaga aaaataagat
     3181 ttgacttgaa tcaaaaaggt ctctatgcta gatatacttt tgatgatttt ttatttaaag
     3241 ataaattaac taaagaattt attgaagaag ctaaaaaaat tggaaaaagt gattatacaa
     3301 ctttacttta tggagaaagt gggtctggta aagaaattat agctcatagt atacacaaca
     3361 taagtaaaag aaaagatagg ccttttgttg ctataaattg tgctactata gcagaaaatt
     3421 tacttgaaag tgaacttttt ggctatgaag aaggtgcatt tactggtgct agaaagggtg
     3481 gaaaaagagg gctatttgaa cttgctcatg gagggactct ttttttagat gaaataaata
     3541 gtctatcctt taatattcag acaaaactat taagagtaat agaggaacgt caaataatga
     3601 gaattggttc tgattatata atacctctgg atataaggat tatagcagca acgaacgaat
     3661 ctttaaccga aaaaatagtt atgggtacat ttagagcaga cttattttat agattgagta
     3721 gtttagagat aaatatacct cctttaagag acagaagaga agatataata cctttgttta
     3781 acaattttgt aaatgaagta ttaaaggatg atggtctcaa tggaataaac agtatagatg
     3841 aaaattttgt tttgactaaa gatgaaatgg ataagctata taattatagc tggcctggaa
     3901 atgtaagaga gttaaagaca atagctcaaa aatatgttgt gacaggtaaa attaaattga
     3961 gacaagatag agattttaaa actaaaaaat tacttcctaa ctctgaagta gacaaattta
     4021 attctgaaac gacagcaagt gtagaagtcc aagatgaatc tataaatata agtaagataa
     4081 atgatggtaa gataagtata gatataaaag aagtaaataa gtatgttgaa gaaaaaataa
     4141 taagtatgct ttttgctcaa ggactttcta aaaatgaagt tgcacaagtt cttggaataa
     4201 gcaggacatc tttatggaag aaatacaata aaaatattta aatataatta catataaatt
     4261 attttgaagt aatgttaatt ttttaaaaca agtgttaaga aaaattaaca ttactttttt
     4321 gcaaattttt atttttttag acaggcatat atatttataa gaaaaatagt taaaacactt
     4381 aatttaataa tgaaaaaaat aataattcta aacaaaatca attttacata aagtgggatt
     4441 tattggcata gtaattgctt aatatataat gtaagagtaa atacaatttt aggggtgatg
     4501 gtatgagtca aagtatggtt ggtaagcatg caatgtggcc aaaagaaaat gatgttatat
     4561 ttagcatatc tggcagagct caagcagcag agaaggcttt tggtatggat aatgtaataa
     4621 atgcaacaat aggcgctcta atggatgatt caggaaaatt aataacaatg aaaactgtat
     4681 atgaagaata taaagcatta gataactgtg agataggtgc atatgcagct cttgaaggtc
     4741 aaccagatta cttagaagca gttaaaaaag tatttttcag agattactta ccagaaggac
     4801 atataagagt attagcttca ccaggaggaa gtggtgcaat aaaattagct gtatggaact
     4861 atactaatga aggagatgag gtattaacat ctgattggtt ctggagtcca tatgtaagta
     4921 tagctgaaga ggctaataga aaagtagtta attaccaact ttttgatgaa aatagaaggt
     4981 ttaattttga gtcgtttaaa gaaaaatttg taaatatagc agaaaaacaa ggtagagtct
     5041 ttacaattat aaacacacca gcgcataatc caactggata tagtgttgca gatgatgagt
     5101 gggataaaat attagactta tcaaaagaag tcgcaaaaga taaagacaaa aagataatat
     5161 ttttcgtaga ttcagcatat attgactttg caggtgatga tgatgtatgt agaaagtttt
     5221 ttaagaaatt ttctaatttg cctgaaaacg ttctcatatt ggttggattc agtatgtcaa
     5281 aaggatttac agcttatggt atgagaatgg gggctataat ttgtatatct tcaagtgaag
     5341 atgtagctga agagttccat tactcatgtg ttcattcatg tagagcaaat tggtcaaatt
     5401 gtaatagaag tgccatggca gtattatcta acattgtaaa tgaccctaaa aaattcaaag
     5461 aatatgagga tgaaaaagaa atatacaaaa acatgcttac tagaagagca gatgtatttg
     5521 taaaagaagc tgaaagagta ggattagaaa ttcttccata tatagcaggt ttctttgtaa
     5581 gtataccatg tgataatcca aaagaagtat gtgaagaatt gactaaacat aatttatttg
     5641 cagttccatt aaaaatgggc ttaagatttg cagtttgtgc agtttctgaa gataaatgta
     5701 agaaagcacc aagtattata aaagaagcac ttgaaagttt agaagtaaaa ataaataatt
     5761 aatttcattg aacaaattgg gtggactatg aatttaataa ttgtagatgg agggaatttt
     5821 atatgaaaca attgatgaca ggtaatgaag caattgcacg tggagcctat gaggctggtg
     5881 ttaaatatgc atctgcatat ccagggactc caagtacaga aatattagaa aatatagcaa
     5941 catataaaga tgcaatagtt gcagagtggg ctccaaacga aaaggtagca cttgaggctg
     6001 ctataggggg ttcaattgca ggagcaagaa caatggcttc tatgaaacat gttggtttga
     6061 atgttgcagc tgatccaata tttacttatg catatacagg ggtaaatggt ggtatggtac
     6121 ttattacagc agatgagccg ggaatgcatt catctcaaaa tgagcaagac aataggatgt
     6181 atgcaaaatt tgcaaagata cctttatttg aaccatcaac tagtcaagaa gctaaagata
     6241 tgataaaaga agcttttgaa gttagtgaaa aatacgatac accagtttta tatagagtta
     6301 caacaagact ttgtcattca aaaggattag tggagtgcta tgatagagaa gaagttgaaa
     6361 ttaaagagta tgttaaaaat gctaagaaaa tggtaactgt tccagcaaat gctcaaataa
     6421 gaaggggcgt tgttgaagaa agaatggaaa tccttaaaaa attctcaaat gaaactgatt
     6481 taaactacta tgaaataaat gatacaaaaa taggtgttat agcctctggt atgtgttgta
     6541 attttgccaa agaagttttt ggaaaaaatg catcatatat gaaactagga tttacaaatc
     6601 cactaccata tgaaaaaata aaagaatttg cagaaaaagt tgataaaata tatgttatag
     6661 aagaaaatga cccatttata gaagaacaaa taaaagcata tggaatagat tgtattggaa
     6721 aagatgtaat accaccatat ggagaaatga caccagatgt tttaagaaaa gctatatttg
     6781 gaaaaacaaa tgatactata gaatacaaat ctgaattagt aacaccaaga ccaccaagtt
     6841 tctgtgcagg atgtccacat agaggattct tctatgaact tggaaagaga aaaaatttaa
     6901 tagttggtgg agatataggt tgttacactc ttggatttgc tcctccatat aatggaatag
     6961 actatgttgt ttgtatgggt tctgcttttg gaactgcaca tggagctcaa aaagttctta
     7021 atatgaagga tgataatgaa aaaagattgg taggtgtact tggagactca acattcttcc
     7081 atacaggaat aaatggactt ttagatgttg tttacaatag aggtaattct atttcggtta
     7141 tattagataa tagaataact ggaatgacag gtcaccaaga aaacccaggt tcaggatata
     7201 ctttacaagg tgctaaaact aaagaagttg atatagaagg attagttaaa gcttgtggaa
     7261 tagaacatgt aagagttata aatcctaaca atttaaaaga agtaaatgaa gcactagatt
     7321 gggctttagc tatagaagat gaaccatcag taataataac aagatggcca tgtgtactta
     7381 aaaaattctc taaagaagat atagaagaat ttaataatcc atttaagact aagtgtaaag
     7441 ttgagcatga taaatgtata ggatgtaaat tatgtttgaa aactggatgt ccagctctat
     7501 catttgataa agagaataag ttatcaaata tagatagaaa tcagtgtgta ggatgtggag
     7561 tatgtgcaca agtttgtcca aaacaagcaa tagttaagga ggaaaaataa tatgactaag
     7621 agtatacttt tggtaggtgt aggaggtcaa ggaactatac ttgctagtaa attattaact
     7681 atgggattga tggaagctgg atatgatgta aagatgagtg aaatacatgg aatgagtcaa
     7741 agaggaggtt cagtttcctc acaagttaga tatggagatt gtgttcattc tccagttata
     7801 gaaattggtg gagcagatat attagtatct tttgaaaaaa tggaagcttt aagatggttc
     7861 aattatttaa aaccagaagg aaaagcttta gtaaataatc ataggataga ttctatgact
     7921 gttttaatcg gaggagctga atatcaagaa agtgatatag atgcagagtt aagtagatta
     7981 aatgcaaaag ttataaatgc agctgataaa gctgaagaac taggaaattc aaaaataatg
     8041 aatgttattt tattaggatg tctagttaaa tctatgcaat tagagtctat tgattgggaa
     8101 aaaattataa gtgaaaatgt taaaccaaaa tttgttgaat taaacataaa agctttccat
     8161 gaaggtatgg aaatggttag caaatagttt ataatagata taaatagact atagaaatta
     8221 aggtgaaagg aagaaaatta tgacttacag aatattagcc ataaatccag gttctacttc
     8281 tacaaaaata gcagtatatg atggagaaga acaaattctt gtgaagacga tagaccatcc
     8341 agctgaagag attgcaaaat ataatactat acaagaccag tttgaaatgc gtaaggaagc
     8401 agttttgaat attcttaaag aaaatagtat agacttaaaa tctcttagtg caatagtagg
     8461 aagaggtgga gttttaccac cagtaaaatc aggagcatat ttagtaaatg aagaaatgat
     8521 tgatgtacta agacatagac cagtacttga acacgcttcc aatttaggtg ctgttgtggc
     8581 acatgcaata tcagaacctc ttggaatcaa ctcatatatt tatgattctg ttgcagtaga
     8641 tgagcttata gatgtagcga gaatatctgg actttgtgga atggatagat caagtgcagg
     8701 gcatgcatta aatactagag caatggcttt aaaatatgct aaggataaag gaaaagatta
     8761 taagagctta aacttaatag tagctcacat tggtggagga gtaagtattt atcttcatga
     8821 aaaaggaaga atggttgata tgctatctga tgatgaagga ccattttctc cagaaaggtc
     8881 aggaagagta cctgctacaa aattagtggc tgcctgttat tcaggtcaat gttcagaaag
     8941 agaaatgact aaaaagataa gaggtaaagg tggtatagtt tcatacctaa atactgtaga
     9001 tgctagagaa gttgaaaaaa tgatagcaga aggaaatgaa gaagcaaaaa ttatttatga
     9061 agcaatggct tatcagttag caaaaggtat tggagagtta gcaactgtag tagatggaaa
     9121 ggtagatgct ataattataa caggtggaat tgcatattct gaaatgttta cttcaatggt
     9181 taaaaagaaa gttgagttta tagcaccagt agaaattatg gcaggagaaa atgagttgga
     9241 atcacttgct tttggaactt taagagtact aaatggagaa gaagaagcta gaatttatag
     9301 tgaaaattaa taagaaaaac taaaaatgtt tatatactaa aaaagtggta tatccgtttt
     9361 ttatacacga aagcttagag tataggtgaa aatgtataaa atttggattg ccacttttta
     9421 taattaaaat tttatcttaa cctaataaat aattctgtaa aatttcgtat ttatatatat
     9481 attttattgg tatttattgt tattattatt atgaggagtg atttttgatg ggaaaaataa
     9541 gtttaaaaag tatgataaga ttattttcag gtttttttat atttgcaatt tcttctgtgc
     9601 ttatgattaa tgcacatgta ggtcttatgc cttgggatgt acttcaccaa ggtttatcta
     9661 taaagctagg cataactata ggtcaggctt ctataatggt aggagttgta attgttatat
     9721 tggatgcagt ttttggtgaa aatataggat ggggtacttt actcaacatg acatttatag
     9781 gaatttttat tgatttagta atattttctg gagtgatacc tcatgcaagc aacacttata
     9841 taggtgtgtt tatggttgtt ataggaatta ttttggcagc tatagcaagt tttctatact
     9901 taggtgtttg tttaggaagt ggaccgagag atgggcttat gattgctctt cagaaaaaaa
     9961 ctaataaatc tgtacgtctt gttagaacaa ttcttgaaat actagcatta gttgttgggt
    10021 ggttattagg aggttctgta ggtattggta cgcttgtaag tgctttaggt ttaggatatg
    10081 tattacaaat agtgtttaga atatttaaat ttgacacaaa attgttgaaa catagattta
    10141 ttatagatga tataagagaa tggaaggaaa agaaaagcaa tgaacataaa tgtaaatcaa
    10201 gtattgtaat aaaaaatgag cagaattaat tatgctaaaa tatatttgta gtttatctaa
    10261 tttatagtaa agtcaaggag attttgaaat ggaattatgg gatttatata atgctgatgg
    10321 aattaaaaca ggaaatgtta taaaaagagg taattctatt gaagaaggtt attaccattt
    10381 ggcagttgaa gtgtggattt taaatagtaa ctctcaaatt ttaattcaga aaaggtctaa
    10441 aagtaaaaag acattgccaa atatgtgggg aatgacaact ggatgtattg tttctgggga
    10501 agacagttta gaaggagcaa ttcgcgaagc aaaggaagaa atagggatag atataactaa
    10561 agatgagatg aaagttttta gaagtatgat tcatgaagat actctttggg atgtatactt
    10621 agttaaaaaa gaatatgata tatccaaagc tattttacag gaggaagaag taagtgatat
    10681 aaagtgggta agcacagatg aaataagaca attactaaaa gagggtttgt tttttgaata
    10741 tccagagata tacgaattgc tatatgagat agataataat aaattaaata tatgatgtag
    10801 agcagatttc agtataagta agattattta aaatgtatct tctctaaatt ttaatattgt
    10861 tttatgaaaa ttaataagtt atttttagta tttttctact tgttttttga gattaaaata
    10921 aaaagggcag tcattataaa gtcataaaaa tttggggagg atttaaacta tggaagataa
    10981 caaaggattg gcacgtgaca gttcaaaata taaaattgtt tctatatctg tcgtagtaat
    11041 tattctaatt acattttggt atatgttaaa tatggtgctt ttaacattta ttatgacttt
    11101 tattttctat aacttgcttg tagccacaag aaaacgaatt aagaagtttt cttctttaaa
    11161 tattccagat tcattgataa ttatagtgtt atatgcacta tttgctatat tgttagtatt
    11221 gattagctat gcagttgtac caataattat agttcaactt acagagttga gtagggtttt
    11281 tagtgatttt gatgtaaatc aatttgctca atctttagga ccaaaattgt atcctattgt
    11341 ctcaaagctg gattttaata aatatatttc acaagcaggg ctacttatag catcaacagc
    11401 aacaaaagtt ggaagttttg gagtaaatat attattggca tttttactga gtttactcct
    11461 tttacttgaa aaaaatgaaa ttaaaaattt tggagataaa ctttctgata gtaagatttc
    11521 ttttatttat aattcgcttg tattttttgg aaagagcttt gttaaaaatt ttggtgaagt
    11581 aatgaaagta caagttatga ttgcctttat aaattctgtt gtttctatga tttttttagg
    11641 tttcatggga ttccctcaaa tatgggcttt aggatttatg atttttgtgt tgggtcttat
    11701 tccagtagca ggagttatag tgtctttgat tccattaact gtaatagcat ttaatacagg
    11761 aggaataaca aaggtttttg gagttttact tatgatttgt atagtgcatg cagtagaaac
    11821 atacatatta aaccctaagt tgatgtcgaa tagaactaaa cttccagttt gttttgtttt
    11881 tattatttta cttgtaggag aacattattt aggtgtatgg ggattactaa ttggagttcc
    11941 aatatttatg ttccttatgg atattctggg tgttaaattt acttctaggt aatatattaa
    12001 aataataatt tatctttata tataaattat aaattgtttt aaaaaagaac ctataaatag
    12061 acatcattaa taaagacatc tatttgatag gttcaatttt gctttgtata aatactataa
    12121 aactaaataa aaagaaattt atttcatttc aaaagtttca caacttgcat ttctttcatt
    12181 tatatgaact ttttcagctt tgcaaagttc atttttattg tatttacatt ttacagcttc
    12241 acaatgaatg ttatctgtat caacttggtt agtttcatta gaacgactag ttataccaga
    12301 tgtatatttg tcttcaaaag aagcacaata agtattttct gtagtagttg cttgcattcc
    12361 atctactttt atactaccag cataacaata tccactagta ttataagcac aattagtagc
    12421 agcacaattt aaattattat ttttcataaa taacctccta agttttattt aaacttatta
    12481 tgtgaagtta tctaaatttt atacacttat ttacaattac atttatcaca tttaacaact
    12541 acatctttgg aagtttccct tcctaaattt ttattaacat gatacacatc aacattttca
    12601 gttgatccac atatagaaca tttaaaattg ttttctagta gggttctttc tttaaataac
    12661 ttccaataca tagaattgat gtaatcatta taatttacct tgaggcatgt ctcaagaaag
    12721 tttatgtata gattgtctaa atctcctgta tttaattctg tatattctgg ttcaaaatat
    12781 tcacaacatc ctctaaaatc gggctttgta tctgaaataa cacatctaat atcatatcta
    12841 tagtctaggc taggcccctt aaatgaaaga tgtgtgcaaa aagaacaaga tgtttctggt
    12901 agattttttt caagttcatg taatttatta ttcataagta ttcctccaaa aaatttattt
    12961 taagtatata aacgaataga ttattttaaa acttttattt atttatatta gagatttagg
    13021 ataaatattc caataaggag taaatactta agtatttatt actgtattaa ataaaaaaga
    13081 ggcaaatcta acttgagatt gcctactttt ttatcatttt ttaataaaat ttattctaag
    13141 tattatttta tttagattta gtcagccaat ttagtatctg ctttgctttt taactttcta
    13201 ccagagcgta cagttaaaat agcatataat acagtaaata tggcagctaa aacatatgat
    13261 atatttatgt ttaagttaaa tccaatttga gcattaaata tataactgaa tataacaaag
    13321 gaataaaaca taccaggaat taagcttata atataattct tttcttttat tataaggtaa
    13381 actgtaatca ttgcaaatgc aaatatggca atagtttgat tactccaaga gaagtatctc
    13441 cacaatatat taaatccaga agcactaagc tttgcaaata taaggatggc tatgacagga
    13501 ataaatatac agattgacaa tataacacga tgtttctttt ccttttggtc ataatgaaag
    13561 taatctgcaa gcattaatct taaagatctt aaagctgtat ctccagaagt tattggtaaa
    13621 acaattacac ctattatagc tatgatacca ccaatagaac caagtaaatc tcttgcaacc
    13681 aaacctatta catcaggaga acctactaat tccttaggta ttcctttatt gtaaataccc
    13741 atagcagctg cagcccaaat cattgcaatt aaaccttcta aaatcatcat attataaaaa
    13801 gtagtttttc cttctttttc atttgaaact gatcttgcta taagagtagc ttgagttgag
    13861 tggaatccag aaacaatacc acaagcaact gtaacaaaga atgtaggaat aagaggaata
    13921 ccatcaggat gaataccttt ccaatttgca agacttaaat tagctaaatc ataaccttgt
    13981 gtaaagattc caattccaac accagcagca gataaaagta gaatagctcc aaatattgga
    14041 tatacctttc ctatgatttt atcaattgga aatagtgttg cacacaagta atatagaaag
    14101 ataagtccat aaactatcca gacaactgga ttatttatag tcgatttcat atttaaaatt
    14161 tgagtaacaa ctaaatcccc aggtgtataa ataaaaactg caccaactaa aagcattaaa
    14221 agacaaagga atatattata gacttgaaat actttattac ctaaaaatct actgataaga
    14281 gaaggcattt gtgctccttt ttctcttata ctaatcattc cactcatata gtcatgcaaa
    14341 gctcctccaa atacacagcc aataggtatt agtatgaatg ctattggacc aaacaatata
    14401 ccttggatag gtcctagaat tggtcctgta ccagctatat taagcaactc aattagacta
    14461 ttcttccatt ttttcattgg gacatagtct actccatcac tttgagcaag tgcaggtgtt
    14521 tttctgtcat ctgggccaaa tactttttca caataagcac cgtataaagc acctcctatt
    14581 agtaatatag ccaagccgat taagaatgtt gtcataatat caccccattt ataaaatttt
    14641 ttggtctttg tatacatatt atctaaatgt gtagatttat attgaattta attctggaca
    14701 acctacaaat tctataaagt attacaacta atataatttc agaaataaat acatatacat
    14761 aaccatgtac ttagtataca ggtatttggt aatattttca atgttatagc aataaagaat
    14821 ataaacaaaa ttctgataat attttacaaa aaaattaaaa aatataaaaa ttagtttaaa
    14881 tagatggaga aaaaggaaaa tcaattgaga atataaatgt ctatatctta acaatattaa
    14941 gaggtttaaa attcttgaag aaagaatagt caagtgatat aatgggttta caggtgtata
    15001 tacactagta catatagaaa gcggtgcaat tatggataaa gatttaacat atcaaatcaa
    15061 agagctaaag aaagaaaaaa atgcaataat acttgcccat ttttatcaac caccagaaat
    15121 acaagaatta gcagatgcag ttggtgactc atattattta agtgagattg ctagagattg
    15181 taaagaagaa gtggttgtat tttgtggagt aaggtttatg ggagaaagtg ctaagatatt
    15241 atcacctgaa aaaactgtat tgatgccagt aagtaacgct gggtgtgcta tggcagatat
    15301 ggtagatgaa gaaggcgtga taaaattaaa acaacagtat ccaaatgctt tggttgtatg
    15361 ttatataaac tctacagcta aagttaaggc acattgtgat gtttctgtta catcttctag
    15421 tgcaattaaa atactagaaa acatagataa taaagaaatt atattccttc cagataaaaa
    15481 tttaggagga tatattgcag aacaatttcc agataaaaac tttatatttt gggacggata
    15541 ttgtaaatac cataacaata taagagctga agaaataatt gagttaaaag ataagtataa
    15601 aaatgcagaa gtattagtac atccagaatg taaaaaagaa ataagagatt taggagatta
    15661 tgtaggtagt acatcaggaa taataaaata tgctactaat agtaaaaaca aagactttat
    15721 aatagcaact gaagaaggta tattacatga attaaagaaa aataatccta ataaaaactt
    15781 ttatattcct ggtggaaaaa tactatgtac agatatgaaa aagacaacat tagaaaattt
    15841 atatagtaca cttaaaaata tggaaaatga agttattgta gaagatgaaa tcatggaaaa
    15901 ggctttaaat tcactgctta acatgcacaa attagcagaa ggatagaggg atagacttat
    15961 gaatttagaa caagatgttt taatagttgg aagtggagtt tcaggattat actgtgcatt
    16021 aaatttagat aaaagtttaa atgtgctagt agtatcgaaa tcaacaattg aaaacaacaa
    16081 tacatatctt gcacaaggtg gaatttcaac tgctagaaat attgatgata tagaatcctt
    16141 tgtagaagat acaatgaagg ctgggcagta taaaaataga gttgaagcag ttcaagtact
    16201 tgcagatgaa tctatagaaa atgtaggtca gatagtagaa tatggtatgc ctttagacaa
    16261 agaaaatgga gagatagatt acacaagaga aggagcacat agtgtaaatc gaatagttca
    16321 tagtaaggat aatactggag aagttgtttt taaaacttta ttaaaagaag ctaaaactag
    16381 agaaaatata actcttatag aagatgcata tcttttagat atattaaaag atggcaataa
    16441 atgtatagga gctagaattt ttaaatctaa aaaagagatt catgtttttt caaaaatagt
    16501 agttttagct acaggtggaa ttggtgggct ttttaaaaat tctactaatc aaagacatct
    16561 tacaggtgat ggaattgcaa tagctttaag aaataatata aaaatagaaa atttagaata
    16621 tattcaaata catcctacag ctttttatga agaaaataat gaaggtagga gaatgcttat
    16681 atctgaatca ttaagaggag agggagctaa acttttaaat aaaaataaag aaagatttgt
    16741 ggatgaactt cttcctagag atgtagtttc aaaagctatt tttgagcaaa tggaaaaaga
    16801 taaattacct tatgtgtatt tagatgcaac acatttagat agtgaatatt taattaatag
    16861 attttctttt atttataatg aatgtttagc tagaggaaca gacataacga aagaatgtat
    16921 aaaggtatct cctgcacaac attattttat gggcgggata catgtagatt tggattcaaa
    16981 aacatctatg gaaaatttat atgcagttgg tgaaattagt tgtacaggtg ttcatggagc
    17041 caatagattg gcaagtaatt cattacttga agggcttgta ttttcaaaaa gagcagctaa
    17101 aaatataaac tcagttatag ataatgtaaa agttaagttt atagatgtac cagatatgga
    17161 tatagatata gaacaggtaa aaaaagaaaa taaaatatta gtcataaaag aaattgaaag
    17221 aacaagtgag gattttggcg atgaattatt tgattattga tagaatgata caggatgctt
    17281 tgatagaaga tgttccaagt gaagatataa caactaattc tattgtggat gaaaattcta
    17341 aatctactgt agatttaatt tgcaaacaag atggtataat agctggctta ggtgtattta
    17401 agagagtttt tgagatactt ggtgatgtag atgtaaaatt atataaaaat gatggtgata
    17461 gagtaaagaa tcgtgaaaag atagctgtat taacaggtag tactagaaac ttacttgtag
    17521 gagagcgtgt agcattgaat tatttacaga gaatgagtgg tatagctact attacaagta
    17581 ggtatgttga aaagcttgaa ggtacaaata caaaattatt agatagtaga aaaacgatac
    17641 ctaatcttag aatattagat aagtattctg ttaaagtagg tggaggatgc aatcatagat
    17701 ttaatttatc tgatggaata ttgcttaaag acaaccatat tggggctgct ggtagtgtta
    17761 agaaggcagt tgaattagct agaaaaaata cttcttttgt tagaaagata gaagtggaag
    17821 tggaaacttt agacatggta aaagaagcaa tagaagctaa tgcagatata ataatgttgg
    17881 ataatatgag tttggaaatg gcaaaacaag cagtagatat tataaatgga agagccattg
    17941 tagaattttc cggaaatgta aatttagata ctatagaaga tataggaaaa attggtgtgg
    18001 atgttgtttc tgtaggagcg cttacacatt ctgttaaagc tctcgatata agtatgaaga
    18061 atttgagaaa tatataaatt ttatattgaa ataaacttaa ttaaaataga ctccttaaat
    18121 ttgttttata aatttaagga gtctattttt tattcattaa aattaataaa aatagaaaaa
    18181 aatcaatcaa taatttaata aaaatagata aatactatat acacttttaa taatatagtt
    18241 aatatctatt ttacagataa ataagaataa acttataata taattgtatc tgtaaaattt
    18301 tgtaaaatat aaaaagtata gggggaataa aaatgaaagt agcttatatt tttagtagta
    18361 ctaatacaca taagattcta gacaaaatga taataccaca acttgaacaa ggaactcatg
    18421 gagtagacgt tctagggatg tttttcttta tggataatac cttattttta tctaaaggta
    18481 atcctgtagg cgagagacta agtaaattac atgaaaaaac tgatatgata ataatggctt
    18541 gtgaccaatg tgctatagaa agaggtatag agaataattt ggttgatgga gctacaattg
    18601 gatgtttccc aaacctatat gcttgtttag gcagtgcagg tgtggaccaa gttataacgt
    18661 tataaattag tataggatac aatccataga aaaatttatt ttctgtggat tattttaagt
    18721 aaaagataaa ttgtttaaag taggggatta acaaatgtct aaaattttag ttgaatttat
    18781 aaacacttga ccatcttgtg atgaacatgg agtgtttata aaaaaaatgt cagaaaagta
    18841 tgctgataaa ttggaaataa aattatatca agcagggaaa gatttttcgt atataaaaaa
    18901 atatgggatt ataacaaaag gaactttaat aataaatcag aaaaagaaat atgatagatt
    18961 aaataaagat acaattgaaa gggcaatagt agaagctata aacaataatt aaaagtttaa
    19021 aaattaggag tatcaaaaat gaatatatta gaaattgttt taaatggagt taaagatact
    19081 atagtagctt ctatagttac actgaatgga gcatcaggat ggcttatgat aagttttata
    19141 ttggcaggtg tacttcacaa tgttttaact ccaagaaggt ttcaaaaaca acttggaaat
    19201 aagaaatttt cttctttaat taaaagtact atctcaggaa tgtttttacc aatatgtagt
    19261 tgtggagtaa taccacttgg aataagtatg tattattcag gagcatattt aggaccagta
    19321 cttgctttta tgacatcaac tccaataata aatccaatag ctgtagttct ttgtctaggt
    19381 cttttaggtc ctaaagttac aatcatttat ctaatagctg gttttttagt accattttta
    19441 gtaggatttt taggaaattg ttttggaaaa gaagaattat cacttcataa tgattcagag
    19501 gaagaagtaa tagaattaga agaagaaaaa agaagtttta tgggaaatat gattgatggt
    19561 cttaaatggt cttttggtga attagccctt actattagta aatatgtagt aatgggtatg
    19621 gtttttgcag gatttataac aactattttt ccaaatagta taattcaaag atatttagga
    19681 aatccaggtt tgctatctct tggaagtata gcaatacttg catgtgttat gtatgtatgt
    19741 gctgtaggac atataccgtt tatagcagcc cttgttgcaa gtggagcatc tcctggtata
    19801 gcgataacat ttctaatagc tggagcagct acaaatctac cagaacttat aagtatgttt
    19861 aaacttattg gaaaaagaac tgttattata tattctgtaa ctttgacact gtcttcaata
    19921 ataattggat atataacaaa tttactttta gtgaataata actcagtaaa tttagatgca
    19981 acaaattctt caatacagtt ggcaaataaa ctaatgttaa acatacctga tagttttgag
    20041 tatgtatgta ctattttaat tattttattt gcatttaaat caataatacc aaagatgaaa
    20101 gaggtcatag gaaatcatgc ttaaaaagat agttataata tcctgtatag tagttgtgtt
    20161 aatcatttta tcaaaaatag ttgatgataa catcaaagaa gatgcttcta ttccaaatgt
    20221 gaataaagaa acattagaat attttagaaa aaattataaa gaagacataa taacttgtgc
    20281 tgaagaagac ttaaataatg atgggaaaaa agatttagta gttatatata aaaaaagcaa
    20341 taattcaaat gaaatggtag tcgtagtttc tgataaaaat agccactata taacaaagcc
    20401 aataccagca cctatagaga atcaaactat aacctttaaa aatattgatg ataaagcacc
    20461 aatagaagta attgtatcag ggtctaaaaa tggtaatgta ggatatgcta tttacagagt
    20521 agagggtaaa aaatttgttg atttatttgg cgaagatatg gacaaatgtt gctaaaaata
    20581 aaaataatac ataaaggtgg gaaatttata tgaaattatc taagaagatt caagcattaa
    20641 tcttatttgg tgtaatgggt acatctatat taacaggatg tagtagtaaa ccaaaagaaa
    20701 aagaagaagc aaaaactgga aaagatgatt atacaataac agtaggttat tataattgtg
    20761 accatatgac tgcgggacca gtagcagaat cggcaggaat atataaagat ttaggtctta
    20821 atgtaaaaac tgttggaaat ggtaaagttc ctgaagctat ggcagcagga aaaatggatg
    20881 caggttacat aggaactaag gggttagttg gagcaatacc taagggttcg ccaataacaa
    20941 tagcagctaa caaccatact ggtggttctg aatatttaat agtttcaaaa gatataaaag
    21001 aacctaaaga tttaataggt aaaaaaattg caacagatat gagtgatttc ttatggacaa
    21061 gtgattatgg tccagaaaca ggtctaccaa ctgacccatc aaaatatgaa gttgtaaata
    21121 tggattcaga caaagataaa tatttagctc ttaaaactgg gaaaattcaa gcttttacat
    21181 cttgtgaccc ttggggttct gtagctgaaa atgacggtgc aggaaaaata atagcatcta
    21241 ctcaatataa agaaaaggct aatggcaaag aatataactg ttgttcattc tcattaaaca
    21301 aaaactttat aaaagaacat ccagatttag caaaaaaatt ggttctagca catacaaaag
    21361 caatagaata tatatataca aatccagctg aagcagctaa aatatttgca aaatattata
    21421 atgtagaaga agaagttgca cttagaacta tctataagaa gactgttgga gaaggtagaa
    21481 ctcttacttg gaaagttaca ggtgaagaat ataaaaataa tttacaaatg tataaagatt
    21541 taaaggcttt agatgatata cctaaatatg aagatacgat tgatacaagc ttattggact
    21601 cttgtggagc tgatgatttt gacaaattta taaaagaaaa agttaaccca gagtttcctg
    21661 aaggtatgag ttatgaagac tggaaagcaa aggtattata aataaatgga gaatatgaaa
    21721 aatataataa tactttttat cattattttg ggaagtatat ttataatatt ttttaatttt
    21781 gaagataaag aagaaataaa aggaaaatta agaatagggg tatctgatga tacctctggt
    21841 tttgtaataa attatatggt aaatagagac tactttgaaa atataaaagt aagtgatata
    21901 atggatattt ttacaattaa tgattgctga gcaagtacaa tgcagtgggc tctgagttca
    21961 gaggaaatag atatagcaat catatgtaaa gatgctgcaa aacaatatgt aaatgtaaat
    22021 agtggatttg aaattgttgg tactgtagtt caaaattctg atatatttct attaagtgat
    22081 aataatcctg aaaagatagg agtcattcaa aatagagatt accagtcaga attggttaaa
    22141 aaatactaca agaatgtgga agtagctccc ttattaggga ctgcactagc atatggatta
    22201 gaaagtaatt tagtagatgg tgttgtaata gattgcataa agtcaattgg gttagagggt
    22261 aaaagaaaat ctacaactaa attaggagat tatgatacct atgtattagt tgtaaataaa
    22321 gagtttaaaa aaagtaaagc atatagtgat tttataacac tttacaataa aagtgttgat
    22381 gctttaaaga ataaagctac atttaagaaa gtattaaaag agtacaggaa tataagaaat
    22441 atagatatgg aggaaataag caattggaaa ttaaaatttc taaagataaa agcgatagat
    22501 taactaagaa aaaaactgat ggtagtatgg atattttata taaaataata ctattagtta
    22561 ttatattttt agtctggcat tttgcagcaa aagatatagg gagttctttg ttacttccaa
    22621 tgccagtaga tgtaataaaa ggtttctttt tctgtgtgac agatgcagag acagtcacta
    22681 atctttttat aacattgcag agagtactta aaggttttat gtatgcatta ttgtttgggc
    22741 ttccaatagg atttattatg ggattttcta aaacttttga aagggtttta tctccagtag
    22801 tagattctgt aaggcaagtt ccaataatgg catgggttcc tcttactata gtatggtttg
    22861 gtataggaga tggtccaaca atatttttaa tagctttttc aggggttttc cctataattt
    22921 taaatactat tcaaggagta agagcaatat caaaggatta ttataatgca gctagaagta
    22981 tgggagcatc gccaattgtg atatttacaa atgtaattgt tcccgcatct cttccagata
    23041 tactaactgg ttcaaggatt gctataagta caggatggat gtctgttatc tgagccgagt
    23101 ttatagctac gagtgctggt ctcggttact caatggtaca agctcaaaca ttaatgcata
    23161 cagatgtatt aattgggctt atgatatttg cagctttaat aggatttata atagataggg
    23221 tattaaagtt tataaataaa atcctttgta gatggaggtt tgcagattaa tgaagttaag
    23281 tgtaagagat ataaataaga catttgtaaa taatagagta catacaaagg ttttagaaga
    23341 tataagtatg gatatagatg atggacaatt tgtctgtctt ttaggaccat caggttgtgg
    23401 aaaaacaact ttacttacta taataggtgg gtttcaaaaa tcagaacgtg gagatgtttt
    23461 tataaatgat aaaagagtta aaaaaccggg catagataga gcttttatat ttcaaaatta
    23521 tgctttattt ccttggaaaa ctataagagg taatgttcta tttcctatga aacagcagaa
    23581 aataccaaaa gaaaaaagag aagaaatgct agaagaactt ttggttatgt cagacttgaa
    23641 aggaaaagaa aaactgtttc cacatcaatt atctggagga atgaaacaaa gagtggccat
    23701 gataagagct ttagcatgta atccagaggt attactaatg gatgaaccat taggagctgt
    23761 agattttcaa atgagacaaa atttacagga agagctagaa cgaatatgga taaagaagaa
    23821 aataactgca ttaatggtaa ctcatgatgt tgatgaagct gtatatatga gtgatagagt
    23881 tatagtaatg tcgagagata aaggaagaat tattgatgat ataaatatag atattccaag
    23941 acctagaatt agaggaagcc aaaaatatga agagtacaaa aacaaattaa ctgatacttt
    24001 atcaaagtgt tatgaagttt aaagaggagt agacatgagt caaatagaaa aatacaatag
    24061 tttggataat acacaacaga aaataagaat ctctattatg gatatgataa tagataaagg
    24121 ttctagtgtt acacttcaag aagtgactga atatataagt aaaaagttga atatagaaaa
    24181 agaatatata gaaaggacac tacaatattt tatttataaa aatataatgg ttgttgatgg
    24241 aaatagtata aattttatat atcctgtatc agcattgcca acaaatcata aagtaacttt
    24301 gagagataat agaagtttca gtgcaatgtg tgctatagat gctataggaa cctcttgcac
    24361 attcaaccaa gatataaaaa taaactctat ttgtagtgct acaggtaagg aaatagaagt
    24421 aattataaaa aatgaaaaga ttgagtatgt gaataatcca aacttaagag tgcttcatat
    24481 aaatcttgat aagcatctaa attgggctgc tagttgctga aatataatga atttcttctg
    24541 gacgaagagt gattttgatg cttggacaaa cgaagcggga ttatctgatg atgaagatat
    24601 atattgttta gatattaatg aggcaatagt agaatcatat aaaatattta aactcaaaca
    24661 aaaggtacta tcatagatat acatatatga aaaactaaaa atgaccttta gataaaaatg
    24721 ataggtaata tccatactat ataaattagt atagagtagg gatgtgaaaa gtatttaaat
    24781 ctaaaggtat atttttagtt tttttagatg attagatagc cttattaagt atatatttat
    24841 ttataacctt tgcaactcca ttttcattat tagtatcagt aacataatct gcaatttcct
    24901 ttatactatt acgtgcattc cccatagcca caccaagacc tgcatacttt atcatatgtt
    24961 ggtcattttc ttcatcgcca acagcaatag cattttctat aggtatattt agattcgtac
    25021 ataatgtttt aagagcagtt cctttattag tagttttacc taaaaattct agataaaaag
    25081 gagcagacct tactatagta tatttattga ataaattttt aggtagttgc tgtatgattt
    25141 cttccaatct ttctggttca tcaactatca taattttaca gattttaata gattcatcaa
    25201 ttttatcttt ttgcatatat ttgacttcta tattatttaa tttcgcttca tgaagtgtat
    25261 atttgccagg cgtttcattt ggtgtaatta aatttgtcat tgtatttatg tgtattttag
    25321 tcttatattt tttacaaacg ttattatata taaaatcaaa atcatctaaa ctcatttcta
    25381 catcatgtat gattttctca cttttaactt cttgaataat tgctccatta aagcatataa
    25441 cataatcacc ttcatctgtt aaatttagtt gatttagaag ttcttttaca ccaggaagag
    25501 gtctgcctgt tgttataact acttttgccc cagccctttt tgcctcctga atggactcaa
    25561 agacttcagg agtaatcctt ttttgtgtat ttaatattgt tccatcaatg tctagtgcga
    25621 ttaatttgta catatcaacc tccaataaat tatatactca aatttcctgt gaaaacgttg
    25681 acacagctag tgttgaacaa agtttcagtg ggaaatatgg tttgttttgt atactattat
    25741 atcaagagat aagtaattta gaaagtttaa taatattaat tttttgataa aaatattact
    25801 tatgtgagat gagaatgtaa aaactttgta atcaataatt ccaaaattct taattacaaa
    25861 taatggtatc gtttgcattg ttaatataaa taaatgtata ttatatagtt agaagtttga
    25921 ataaatagac tgatggtaat ttgttatatt agttagtttt gtgttataaa atattgtaat
    25981 tccattaatc atatgttatt attcaacatg attataatat aaagaatatt tgatatatat
    26041 aataatttat aaaagagtat tacatagtac atgtaaatct atatttataa atacaataaa
    26101 gtaaagttgt aaaggagtgc tttaaatgaa gttttcagag tttaagtatg aaagacccaa
    26161 ttataatagt atgaaaaaag agtttttgag ttgtgtagaa gatataaata attctcgtaa
    26221 ttataaagag caacaaaaaa atatacataa gattaattta ttaagaaata aaatagaaac
    26281 gttgtcaaat atagcgtcga taagatatag tacagacaca tttaataaat tctacaaaga
    26341 agaaaaaaat tattgggatg aatatatgcc tttgtatgaa gaattaaatt cacattttta
    26401 taatgccatt gtaaattcaa aatttaaata tgatttgata aaagagtttg gagagcaatt
    26461 tttcacaata gtagagtatt ctttaaaaag tttttccaaa gaaataataa gtgaattgca
    26521 ggaagaaaat aaattgtgtt cagagtatac tagactttta gcttcagctg agataatgtt
    26581 tgatgggaaa ataagaaatt tatctggtat ggggaaattc atgtattcta agaatagaaa
    26641 aacaagagaa ttagcaaaca aagcatatta taatttcttt gaagaaaatg aaactaaatt
    26701 tgatgacata tttgataaat tggttaaact tagagataag atgtctaaaa aattaggttt
    26761 tgaagatttt gtagagcttg ggtacgttag aatgatgaga agtgactaca gagaatatat
    26821 gataaaaaat gttagaaaac aagtactaaa atatgttgtt ccaatggtaa atgaacttta
    26881 tgaaaaacaa gctaaaagaa ttggtctaga atatttaagt tacatagatg aaggcgtgga
    26941 atttttaaca ggaaatgcaa gtttaaaggg agattcaaga tacataattc aaaatggtaa
    27001 aaggatgtat tctgaactgt caaaagaaac aaatgaattt tttgatttta tgttagaaaa
    27061 tgaacttatg gatttagaaa cgaagaaagg aaaaggagct ggagggtatt gtacttatat
    27121 accagattat aaatcaccat tcattttttc taattttaat caaactgctg atgatataga
    27181 tgtgttaaca catgaggcag gacatgcatt tcagttgtat atgtctagat ggattgatat
    27241 gccagaaatt aattttccaa cgcttgatag ttgtgaaatc cattcaatga gtatggaatt
    27301 tataacatgg ccgtggatgg atttattttt taaagaagat acagataagt acaaattcac
    27361 tcacttatca tcttcaatta aatttatacc ttatggagta attgttgatg aatttcaaca
    27421 ctatatttac aaaaatccta atgtagataa gtcaaaacga aaagaaatct ggagattttt
    27481 agagaaaaaa tacttacctc atagaaaata tggtgataat tcttttttag agagaggttg
    27541 ttggtggttt aaacaaggac atatatttaa aaatccgttt tattatatag attatgtatt
    27601 agctcaaatt tgtgcgttac aattttggaa aaaaatgatt caagatagag atgcaggatg
    27661 gaaagattat ataaatatct gtaaagttgg aggaacaaaa tcatttttag atattgtgag
    27721 tatgggaaat ttgtattctc catttgatga tggctgtatt gagtctatta taggtgatgt
    27781 taaatcttgg tttgatgaaa taaatgacag caaattataa aaaattatga gaattttatt
    27841 gtataaaagt gaaaaattaa aaaatatata aaaagtgatt atttgttgtg aaaatagtct
    27901 tgtttttaac taaattgata aaataaacta aaaaagattt gtacttaaaa aaaaaagaaa
    27961 atacaagaaa tatgcaatat caacatttgg aaaaaaaagt aaaaatgtat acaaaataca
    28021 tataaaaaaa ctattgcaaa ttttatagaa tgtttatata cttaagtcaa cagagataga
    28081 aaaaagctat ttatagaaaa caaaggataa attgcttaat tttaaatttt ctgaaaaaaa
    28141 taataatccg gatgaagagt atgggagact gctttataaa aagcgaccga agggacaagt
    28201 ttaatcttac ttacccaaaa gattagatga aattctcagg taaaggtgac tgtacttgga
    28261 cggggctctg aaaatgattt taacagggaa gacaaattgg gagatttgtt tttcctgttt
    28321 tttatttatc aagtaataaa taaaagtttg aaagagagta aaaaaatgat aataattacg
    28381 aataatccaa aagtaaaaga agaagttcaa ggcagagaag ttttgtttaa agacacaact
    28441 tatattggaa tcttagaagc aagtagagat ttgatacatg aaggttatga acttttatct
    28501 catccactct atgggagtgt aaagccaaat gaaacacctt acaggactgt tatactaaag
    28561 aaaggaaatc gtttggatat aaactcttta accttaattg aagaagcaat catcactgca
    28621 agtaaatttc agaataataa aaagactcca aaatggacag aaagtgttca agatgatttt
    28681 agagtaattg attatgatat attttataat acaatacaaa gaatgcagta tgaataaaaa
    28741 aaattgttaa aaagttatta aaacagccta aatattaaat ctaatttaat attaaataaa
    28801 atgagaaatt taattgggga ggataagtca aaatggaaaa tgtgtatgac ttagtaataa
    28861 ttggttcagg accagcaggg cttgcagcag gtctttatgg agcaagagca aagttaaaaa
    28921 ctctaatcct agaaaaagac aagactggtg gacaaattgt aataacacat gaaattgcaa
    28981 attatccagg gtcagttcca aatgcaacag gaccaagttt aatagctaga atggttgaac
    29041 agtgtaaaga gtttggagca gaaatgctaa gagacaacat tgttgatact gagctagatg
    29101 gagatataaa agttttaaaa ggggaaaagg cagaatatag agcaaaagca gtaataatag
    29161 gaacaggagc aacaccaaga aagattggtt gtcctggaga aaaagaactt actggtaaag
    29221 gggtttcata ttgtgcaact tgtgatgcag atttctttga agattttgaa gtatttgttg
    29281 taggtggagg agacagtgca ttagaagaag caatgtattt aactaaattt gctagaaaag
    29341 taacaattgt acatagaaga caaggattta gatgtgctaa gagtgttgaa gaaaaagcaa
    29401 aagctaatcc aaagatagag tttttattag atacagtaat tgaagaaatc aaaggtgatg
    29461 gaatattaga atcagttgta tttaaaaata aagttactgg agaaactcat gaatactttg
    29521 cagatgaaga agatggaaca atgggagtat ttgtgttcgt tggattagat gctcaaactg
    29581 atttattcaa aggtaaagtt gatatggatg aaaaaggtta cataataact gatgaagata
    29641 tgagaactaa cataccaggc gtatttgcag caggagattg tagatctaag actctaagac
    29701 aggttgtaac tgcaactaat gatggagcaa ttgcatctat agtagctgag aaatacattg
    29761 atgaaaaatt tgggaactag aatctgtaaa ttaagaaata gtgtctgtaa atttaatgaa
    29821 taatatttaa aattaaaatt aatatttaaa attaaaataa aaatttcaag ggggaataag
    29881 aaaatgttag atttagataa ggctacattt gaagaagaag ttttaaatgc agaaggtttt
    29941 gtatttgttg atttttggag tgaaggttgt gagccttgta aagctttaat gccagatgtt
    30001 cataaattag ctgagactta tggggataaa ataaaattct gtaagatgga tacaacaaaa
    30061 gctagaagat tagctataaa acaaaaagta ttaggtcttc caactatggc tatatataaa
    30121 gatggagaaa aagtagacga agttactaag gatgatgcta cagttcctaa tatagaaaac
    30181 atgattaaaa aatatcttta atatgttgat aaattattaa cattaaaaga aaaaatctat
    30241 ttttatctga agataagaag aaaaaggttt ttatgtccaa ctttgttaaa aaaataattt
    30301 taaataaaat aattttttta caataaatat tttttagtaa taaaataaag atttaaggca
    30361 taaaaacaca ataatatatc tttaaaaaaa taagataaat tgtaaaatga tataattttg
    30421 agaaaaactc aaatgcatat acacaaatta aataacagga ggtgcaagta tgcgtcttga
    30481 attagggaaa atctttataa aagatattca atttggtgat gtaacagaag taaaagatgg
    30541 agtattattc atcaataagc aagagatgct acaagaaatt ggtggagatg agcatattaa
    30601 atctatagat atagaattag ctcgtccagg tgaaagcgta agaataacac ctgtaaaaga
    30661 tgttattgag ccaagagtaa aagttgaagg taatggggga atcttccctg gtatcatgtc
    30721 taaagttgac actgtaggag aaggaaaaac tcatgcttta aaaggtgtag ctgttgtaac
    30781 tactggaaaa atagtaggtt tccaagaagg tataatagac atgactggag aaggagctaa
    30841 gtatactcca ttttctaaat taaataatgt agtagtaata gctgaaccta ttgatggttt
    30901 aaaacaatac gctcatgaaa aagctgttag aatgatagga ttcaaagcag caatgtactt
    30961 aggagaagta gcaagaaatc ttactccaga tgaagtttca gtatatgaaa ctaaacctct
    31021 tcttgaatca ataaaagaat atccagagct tccaaaagta ggatatgttt acatgcttca
    31081 gactcaaggt ttattacatg atacttatgt atatggagta gatgcaaaac aaatagtacc
    31141 aactttatta tatccaacag aattaatgga cggagcaatt gtaagtggta actgtgtttc
    31201 tgcatgtgac aaaaacccaa gttatgttca tataaacaat ggggttgttg aagacttata
    31261 tgcaagacat ggtaaagata taaactttgt aggtgtaatt ataactaatg aaaatgttta
    31321 cctagcagat aaagaaagat cttcaaactg gacttctaaa ttatgtaaat atttaggatt
    31381 agatgcagtt atagtttcac aagaaggttt tggaaatcct gatactgacc ttataatgaa
    31441 ctgtaagaag atagaaatgc aaggtgttaa aacagttata gttacagatg aatatgctgg
    31501 acgtgatgga ggttctcaat cacttgcaga tgcagatgta agagctgatg ctgttgtaac
    31561 aggtggaaat gccaaccaag ttgtagttct tcctaagtta gataaagtta ttggacattt
    31621 agaagtagta gatgtaatag ctggtggttc tgatggaagt ttaagagctg atggaactat
    31681 tgaagttgaa atccaagcta taacaggtgc aactaatgaa acaggatttg gtcatttaac
    31741 tgctaaagga tattaagaag tattttatta aacgattgag taatgttaat aaaacatatt
    31801 atagataatt ataataagtg ttatagatat ataaaaatat attagaaata taataaggag
    31861 gattattatg agtttactta gtaataaaaa ggttcttata ataggtgacc gtgatggtat
    31921 accaggacct gcgatagaag aatgtgtaaa aacagtagaa ggagcagagg ttgttttctc
    31981 atctacagaa tgctttgtct gaacagctgc tggggctatg gacttagaaa atcaaaacag
    32041 agttaaagat gctgctgata aattcggagc tgaaaatgtt gtgattttac taggtgctgc
    32101 tgaagccgaa gctgcaggtc ttgcagccga aacagtaact gctggagatc caactttcgc
    32161 tggaccactt gctggagttg ccttaggatt aagtgtttac cacgttgttg aggaaccaat
    32221 aaaatcatta tttgatgaaa gtgtatatga agaccaaata agtatgatgg aaatggtttt
    32281 agaagttgaa gaaatagaag aagaaatgtc tggtataaga gaagaatttt gtaaatttta
    32341 atgcctaaaa gcaaaagggg tgaaactaag agatgggaaa actaaaagca gtacattata
    32401 ttaatcagtt ctttgctggt ataggtggag aagaaaaagc tgatactaag ccacatgtgg
    32461 cagaaacttt acctccaata agtttacaac ttgataaatt attaggtgaa gatattgaaa
    32521 tagttggaac agtagtttgt ggagatagct atttcaatga gaatatagat agtgcaagtg
    32581 aagaagtttt atcaatggta aaaggttttg aaccacaact tttcatagct ggtcctgcat
    32641 ttaatgctgg tagatatggg gttgctgctg gaacaataac taaagttgta aaagatgctt
    32701 tgaatatacc agctttaaca ggtatgtatg ttgaaaatcc aggagcagat atgttcaaaa
    32761 aggatgttta tgtagtagaa acttctgatt ctgcagcagg tatgagaaag gcacttccta
    32821 agatagctaa acttgcagta aaacttgcta atggagaaga aattggaact cctaaagatg
    32881 aaggatacat agctagagga ataagagtta actacttcca tgaagacaga ggttctaaga
    32941 gagctgttga catgttagtt aagaaaataa aaggtgaacc atttgaaact gaatacccaa
    33001 tgccaaactt tgatagagtt gacccaagta aagctgtaaa agatttatca aaatgtaaaa
    33061 tagctttagt tacttctggt ggtatagttc caaaaggaaa tccagataga atagagtctt
    33121 cttcagcttc taaatatgga acttattcta tagcaggagt tatggattta acagaagaga
    33181 cttatgaaac tgcacatggt ggatatgacc cagtgtatgc aaatttagat gcagatagag
    33241 tattacctgt tgatgttctt agagatttag aaaaagaagg tgtaattgga aaattacatg
    33301 agactttcta tacaactgta ggtaatggta catctgttgc aaactctaaa aaatatgctt
    33361 ctgaaattgg agcagcatta gtggctgatg gtgtagatgc agtaatatta acttctacat
    33421 gaggtacttg tactcgttgc ggtgcaacga tggtaaaaga aatagaaaaa actggacttc
    33481 cagtagttca tatgtgtaca gtagtaccta tttcattaac agtaggggct aatagaatag
    33541 ttccaactat agcaatacct catccacttg gaaatccagc gcttgaccct acagaagaaa
    33601 aagccctaag aagaggcctt gtagaaaaag cattaaatgc tttaactaca gaagtagatg
    33661 gtcaaacagt atttgaaaaa taaaaataac acacacatat attatataga taaaaatata
    33721 aacacacact aaaaataaaa aataactata cacaaaaaaa ataatataga tttcatgaat
    33781 ggataaattg gagttattca ttcatgaaat cttaaaaaat gccaaaatac ataaacaata
    33841 atagaatcaa atatacaata aaatacaatg attagagctt ttaataagtt taataagatt
    33901 aataagatta aaaaataagt gttcataaaa tttatggagg tgcacaaaat gacttatcca
    33961 gttttaaaag gggcaggcta tgtacttatt catactccag atatgatagt gcaaaatgga
    34021 agtacttgta cagttgaaag agcaacaaat ccagattcag aatttttaaa agaagtaagt
    34081 aatcatataa gaagttatga agatgtagtt aactacatgc caaatcaagt ttatatagga
    34141 aatagaagac cagaagaatt aagagattta ccaatgccat ggtgtgaaca aaagattgag
    34201 ggaactagaa atggtaagtt tggagaaata atgcctcaag atgagttcat agctttaatg
    34261 caaataagtg atgcatttga tttagtaaaa ttatcacaag aatttattga tgaagtaaag
    34321 ccaaaaatcg aaaataacta ccctgaaatt gcaccatttg taggtaaatt aaagggtgat
    34381 gatatagaag aaggtaaaga attagtagca acacacatag ctgaaggatt ataccatgat
    34441 ggaaaatttg ttggttatgt aaaaagagca catgatgtag atgttaactt aaatgcccat
    34501 acaatgtttg aaaatctagt agtaaaagca tctggagttt tatctgctat tcaaatgcta
    34561 agacatagca aaatagaccc tgctgaaata gattatgtta ttgagtgttc agaagaagct
    34621 tgtggagata taaaccaaag aggtggagga aactttgcta aatcaatagc tgagatagca
    34681 ggacttcaaa atgcaactgg ttctgacaca agaggatttt gtgcagcacc aactcatgca
    34741 ttaattcaag cagcagcttt agtaaaagct ggtatacata aaaatgtaat ggtagtagca
    34801 ggtggagcaa gtgctaaact tggaatgaat gctaaagacc atgttaaaaa aggtcttcct
    34861 gtacttgaag atgttgttgg aggatttgca gtacttgtat ctgaaaatga tggtgtaaat
    34921 ccagttataa gaactgattt aacaggtaag catactgttg gaactggttc ttcaccacaa
    34981 gcagttatga cagcacttat aacttcaggt cttgatagag ctaatttaaa aataacagat
    35041 gttgatgtgt attcagttga aatgcaaaac ccagatataa ctaagccagc aggagcagga
    35101 gatgttccag aagcaaacta caaaatgata ggggcacttg ctgttaaacg tggagactta
    35161 gaaaagaaag aattgaaaga ttttgtttct aacaaaggat taccaggatg ggcaccaact
    35221 caaggacata taccatcagg agctccttat ataggatttt taatagatga tttaactaca
    35281 ggaaatagaa atagagctat gatagttgga aaaggtagtt tattcttagg aagaatgact
    35341 aacttatttg atggagtatc ttttataact gaaagaaata caggtgttac tgaagagact
    35401 tcaggaatat ctaaggatga aattaagaag ataatagctg aatctatgaa aaaactagca
    35461 ttagatatgt tagaagaata ggggtgagga tatgtcaaaa aaagtaatcg cagatgtatt
    35521 cttagaagta gctaatgcaa tagaaagcgg cgaatttggc aaaaaagtaa aaattggtgt
    35581 tactacactt ggaagtgaac atggtgtaga aaacatggtt aatggtgcac aattagcaaa
    35641 atctaattta tttgatattc tgcttattgg accaaaagtg gaaactgacc ttgaagtagt
    35701 tgaagttaat gatgaaaaag aaatgcatgc aaaaatggaa gaattattag attcaggata
    35761 tattgatgct tgtgttacta tgcattataa ttttccaata ggtgtatcta cagtaggtag
    35821 agtaataact ccagcaaaag gaaaagaaat gatacttgca acaacaacag gaacaagtgc
    35881 tactaataga atagaggcaa tggtaagaaa tgccatttat ggtattgcta cagctaaatc
    35941 aatgggtaac aaatgcccaa aagttggaat acttaatgtt gatggagcaa gacaagttga
    36001 gaagtgctta aaagaattaa aagataatgg atatgacatg gagtttgcgg attcaattag
    36061 agcagatggt ggatgtgtaa tgagaggtaa tgatttactt gtaggtgcac ctgatgttat
    36121 ggttactgat acattatctg gaaatatatt tatgaaagta ttttcttcat atactacagg
    36181 tggagattat gaagctcaag gctttggata cggacctgga gttggagaag actatgatag
    36241 aaaggtactt atagtatcaa gagcatcagg ttctccggta gtagcaaatg ctttaaaata
    36301 cgcttatgat gttgtaaagg gagatataag taatgttgca agaaatgaat ttgcaaaggt
    36361 taaaaaagca aaatttgatg acattatatc ctctcttact aaaaaagaag ttaaagctga
    36421 aaaagtagaa gttaaaatgc cagataagga aattgttact cgtcaaatag ctggtgttga
    36481 tataatggat ttagaagatg cagtatctga gttatggaaa aacggaatct atgctgaaag
    36541 tggtatgggt tgtacaggtc caatagtttt agtaaatgaa gctaaaggag acttagcagt
    36601 tgaaacttta gttaaagctg gatatactgc aaaataagta cattttttat atgtaaataa
    36661 gaacatatag ttataatttt attgattata attatatgtt ctttttattt tatatcttgt
    36721 caatatttat atattaacac aatccattta tttgattctc tagctaattt attatattta
    36781 ttcaattaaa attaagcttt ctaactaaat aaaaactaat gaagtattaa aatgaaattg
    36841 ataaaatatg aaaaaatttt aggaataaag tatctgttag ataaaaataa gattaattag
    36901 tgatataata taattaagat aaaatttatt atttggaggt aaaatcatga gcagagtaaa
    36961 aaatgtagta gaattgttgg aaactaaagg tgttgatgca ctatatctaa caaagaaaac
    37021 taatgtaaac tatataagtg gttttcctga tgaagaagca tatgcagtga tttgcaaaga
    37081 tggaaacttt ttagttactg atagtagata tatggagctt gcagaaaagg tttgcaaaga
    37141 ttttgaaatt ataaattggc ataattttga tagaagtgtg gcaaaggcag ttaaaagtgt
    37201 atgtgataaa gtgggtataa agaaacttgg gtttgaaaga actaatatag tgtttgataa
    37261 atatgaagaa cttaaaaatc tgattgagaa ggataatgga gaattaatac ctacagaaaa
    37321 tattgtagag actttgagat atgcaaaaga caaagatgaa atcaaaaata caagaaaagc
    37381 ttgtgaaata gcggataagg cattagaaga attgattcca catataaaag ctggagttag
    37441 cgaaattgaa ctggctacaa agttagagta ctttatgaaa atgaacggag cacaaaatat
    37501 agggtttgaa actatactga tatcaggagc aaagacttca ttgcttcatg gtaagcctag
    37561 tgataagatt atagaaaaag gtgattttgt acttatagac tatggtgcta tgtataatgg
    37621 ctatatatct gatacaacta gaacttttat agttggagga gcttctgaaa agcaattaga
    37681 aatatataat ttagttaagg aagctcaaaa tgtaggggtt gagaacatga aagctggtgt
    37741 acatgcgaca attccagatg ctgagataag aaaagttgtc aaaaaatatg aagactatta
    37801 ctatcaaggt ataggacatg gagtcggtag agatgttcat gaagaacctt tcattggtaa
    37861 ttatggtgat aaaatcatag aagagggatg tataataaca atggaaccag gtatttattt
    37921 ccctggatgg ggtggagtta gaatagaaga tactgttttg attactaaaa atggtccaga
    37981 aagacttact aaattcccta aagatttgat gattttagac aaataattta atttatatat
    38041 attttttaca taaaatataa cataatctca ctattaagct ctatttacat attatagtaa
    38101 agagggctta attttattgt gagaggtgat agtatatatg tataaaaaac ataaatttat
    38161 aaaaaatata aaaaaagcct ggtataaaat caaattaatt gatagatgcc ttataattgt
    38221 aatggcaata ttaatgtttc aatctatata taatttattt gttaatgaag taaattcaca
    38281 agatactaca actattgatg tagtagtaag aaccacttca gcagctatat ttgggtattt
    38341 tttaagtgct aattttataa agagaccttt aaggaagtat acaaatactg atgtatcttc
    38401 aaatcttttt atagataata atttatcccc aaaaggtcaa gagtctagtc aaaataatat
    38461 aatgaatgtc aaaaatacca ttggatttac ttcagaagct gataattatg aaaagaaaat
    38521 acctattaat aataatgaag gttttgaaga aggagaaact agtgaattgc aaattattat
    38581 agctactgta atttgtatag tagcattaac agtacttttt gttgtaagaa attttacaac
    38641 tacaacatca gcttctttag gtactatttc acagatgaga gattttgtct caggatgcgt
    38701 gggttttttg ctaggttgtc caagtaaacc tgattaaaaa agtattatca ataaaaggta
    38761 ttttaaaaag tatcagtata ataatattta gatttaaatg tatacaatta taattctata
    38821 acattctata ttgtattttt atactgatac tctaaactat actatttatt aaaatatttt
    38881 aacattgtat ttaaacaaaa tattatatct gtataatata aatttagttt atatgaatag
    38941 atgccatata atcaataaaa agtttcatac tatgagatat gtattgattt cttctccaaa
    39001 gaaccccaat atttgcagta attgcacgtt ctaatggtat tgaacagaga ttttctgtat
    39061 tttgaaatat ttctttatac aatattgttg aagccaagtc attttctagt aaataacgta
    39121 tggtagaaag ttgatttgag tgtaaaatta tatttggctt agctttttca agtctttttg
    39181 taataatctt atagtgataa gaaccttcag ataagattac aaaaggtaca ttttttaaca
    39241 tataattcga tataatggga tgttttgcca attcattttt gggatttgta actaagtata
    39301 attctgtttt atagattgtc tttgaatcta tatcatcata aatatcactg tcaattatac
    39361 caatacaaaa atcaagtgta gattcttcaa tcattttagc tccaacaaat gttggaactt
    39421 caaaaatttt aagctctata tctggataaa ttacattaaa tctaggaagt atttttgaaa
    39481 gcaaaaacgt acctaaaact gtaggaatac ctattttgag agaagctttt ctcttttttc
    39541 ctaaatcaag tgcgtcacat tgaaaatcct caaattgttt tataaaatgt tttgacttgt
    39601 ctaaaaaaat ttttccttca ggcgttaact ctattttatt acctattctg taaaaaagtt
    39661 caaagccaag ttctttttct aattctttaa ttgctaatgt tatggatggt tgagaaatat
    39721 gaatactttc tgcagcctta gtcatgtttt tatatttaca gacagtttga aaatagtata
    39781 aatagtttat attcatttgg tattagttcc tttcatttac atattagtga caagtatata
    39841 attaacaata gcataagttt tgtatattgt tgtaaaaaaa tagaatagtt ttaaactatc
    39901 atagcataag tttttgatat tttcaatcta ttaagaatag tgctattatt aaattaacaa
    39961 aagagaatag ctggtatggt ttagagtaaa tcaatctata ttacagttat atcaacgaat
    40021 atcaaaaaat tatctattag aaaataaaaa ttatttttac aattaaattg ttaattaaat
    40081 cataaagaaa aaagtgatat taacaagata aaattttttt aatcagaaat gttaatttaa
    40141 taacaaaata gagtattggg gagaaaggag aaatatattt tttaataata tttgttaatt
    40201 taataacgaa aaatgaaagg gagtgattta gtgaagtttg aattgatgga ttttttaatg
    40261 aatccttttg tccttatgtt tgctgcagta attacaggaa ttttatttgg aaaaattaaa
    40321 tttgggaagt ttaattttgg ggtatcagga gcattattta caggattatt tattggatgg
    40381 cttgcatata gcttggggaa tctaataata gcaaaagggg aaacagcagc aggatataag
    40441 gcagcaactg taatgatggg gaatggaatt atttcttctg acttctttga tttcttttta
    40501 ataatatttg ttgcagcagt tggtctattg gcagcaaaag atatgaaagc tgtattaaag
    40561 aagtatggag caagatttgt aattttagga gttcttataa cttttatagg tggctctatg
    40621 acttatgcaa tgactttact atcaagtgat aaaggaagta gtgcttatga agtttctggc
    40681 gtttacacag gagcattaac aagttcgcct ggattagctg ctgctttaga aacagctggt
    40741 aaacatgcag aagatgtatc aaaagaattt gaaaaagctt caataaaaga taaaaaagaa
    40801 attttaaaag tagtcgaccc agaaggcaaa ttggatgtga atacaactac atcactgact
    40861 caagagcaaa tagataagta tattgcatat gctgaagctg gtgttggtat aggtcatgca
    40921 gtcgcatatc cttttggagt tttaatagta atcttaggtg taaatttcct tccaaaatta
    40981 tttaggatgg acctaaaaga agaaagaaga aaatatgaga aggaaatgaa ggaagcaaga
    41041 gatagtgttt ctggtaaaac gataccagaa gttccattta atataataac atttttcttg
    41101 acatgtttag ctggatactt agttggagga atacatgtat ttatgggacc actagggtac
    41161 ttcacactag gcgcaacagg aggttcacta attgtatctc tagttcttgg atatataggt
    41221 aagatagggg tagtaaattt cagaatggaa gaaaaggttt taaatatttt aaaacaaata
    41281 gggctagtat ttttcttagc aatagttgga ttaagatatg gtggaaaagt agttgattca
    41341 attatgacat ctggtatgca cctagcctta gtagcaatag cagtaggtgt tacagctatg
    41401 atgataggat tcttagttgg caaatacgta tttaaattaa attggatttt attatctgga
    41461 gctgtctgtg gtggtatgac atcaacacca ggtcttggag ctgctgttga tgctcttgat
    41521 agtgatgacc cagcagcagg ttatggtgct acgtatccat ttgcattatt aactaaagtt
    41581 atattggtta tagttttaca caaacttcca atgtaaataa gattttatat ggggggatat
    41641 ttatgaataa tgaaggagca tttgaagaat taagtggaag attaagaaat aaagaattgt
    41701 gtgatttaat aatgaatgca gatgaagctg ctaaaattat agaggatggc atggttattg
    41761 gagttagtgg atttacacct tcaggctatc caaaagcagt accattagca gtttcagaaa
    41821 gagctaaaag tggagaaaag ataaaattaa ccgtatattc aggagcatct ttaggcccag
    41881 aagttgatgg agcatggtca gaagcaggta taattgaaag aagacttcct tatcaaacta
    41941 attcaatact tagaaataat attaataaag gtgttgttga ttatatagat atgcacctaa
    42001 gtcattctac tcaattttta aattatggaa ctatacctaa agtagatgta gctatagtag
    42061 aagcacttgc aataactgaa gaagggaata ttataccaac tagtgggata ggtaattctc
    42121 catcttttat aaaaagtgca gataaagtaa tagtagagat aaatcttgca aaaccaatgg
    42181 aaatggaagg tatggcagat atatatatta cggaaaatcc accaaataga aaaccaatag
    42241 aaataaatca tcctaaggat agaattggaa caacatatat accttgtggt ttggataaaa
    42301 ttgcaggagt agtaattacc aatatgcaag ataagacccg tccattgggg gttgtagatg
    42361 aagcttcgaa aaaaatatca aataatatta ttgctttttt aagagaagaa gtaaaggcag
    42421 gcagattatc aaagaattta cttcctcttc aatctggtgt aggaagtgta gcaaatgcag
    42481 tattatatgg attatgtgaa tctgaatttg aaaatttaac ttgttataca gaggttgtac
    42541 aggactctat gttggattta ataagaatgg gtaaagttac aatggcatct actacatctg
    42601 taagtccatc tccagaagga ttaataaaat ttgaaaaaga tattgatttt tttaaggata
    42661 agattatatt aagacctcaa gaaattagta acaatccaga aatagccaga agaattggtg
    42721 taattgcaat gaacactgca attgaagttg atatttatgg aaatgtaaat tctactcaca
    42781 taatggggtc aaagatgatg aatggaattg gtggttctgg tgattttgct agaaatggag
    42841 caataactat atttagtact gagtcgattg caaaaaatgg tgatatatca tcaatagtac
    42901 ctatggtatc tcacgtagac cacactgaac atgatgtaat ggtaattgta acagaacaag
    42961 gatatgctga tttaagaggt cttgcaccta gagaaagagc tataaaaata atagaaaatt
    43021 gtgcccatcc agattataaa gaacaactta gggattattt aaatagagct tgtaaaagtg
    43081 gagcaaaaca aacacctcac atattggacg aagctttatc atggcatagt aaatttatga
    43141 gtacaggtac aatgaaaaag gctgaaactt ttaaaagtgc attataaaat atttaataaa
    43201 ttggaggtag attttaaatg gaaaaagcag tggaaaactt tgaagattta agtaaggaat
    43261 acattaatgg ttatattgag agagcaagaa aagctcaaag agagtttgaa tgttatactc
    43321 aagaacaagt agataaaata gtaaaaatag ttggaaaagt agtgtattat aatgctgaat
    43381 atttagctaa acttgctgta gaagagactg gaatgggagt atatgaagat aaggtagcta
    43441 aaaataaaag caaagcaaaa gttatatata acaatttaaa agataaaaaa tcagttggta
    43501 taattgatat agatagagaa actggaataa caaaggtagc taaaccagtt ggagtagtag
    43561 cggcaataac tccttgtaca aatccaatcg ttacacctat gagcaatgca atgtttgcac
    43621 ttaagggaag aaatgcaatt attatcacac ctcatcataa agcaattgga tgtagtacaa
    43681 aaactgtaga gatgattaat gaagaattag aaaaaatagg agctccagaa aatttaatac
    43741 aaatacttga ccaacaatca agagaaaata caagaaattt aatttcatca gcagatgtag
    43801 taattgccac tggaggaatg ggaatggtaa aagctgcgta ctcaagtgga aaaccagcac
    43861 ttggtgtagg ggcaggaaat gttcaatgta tcatagatag agatgtagac attaaagaag
    43921 cagtacctaa aatcatagca ggaagaattt ttgataatgg tatcatttgt tcaggtgaac
    43981 agtcagtaat agtagcagaa gaaatgtttg ataaaataat ggatgaattt aaaaataata
    44041 aaggttttat agttagagat aaagtacaaa aagaagcttt cagaaatgct atgtttgtaa
    44101 ataaatctat gaataaagat gcagtaggtc aatcagttca tacaattgca aaaattgcag
    44161 gtgttgagat accagaagat acaaaaataa tagtaataga agctgatgga ccaggagaag
    44221 aggatattat tgcaaaagaa aaaatgtgtc cagttatatc tgcatacaag tataaaagtt
    44281 ttgaagaagg tgtagctatt gcaaaagcaa atttaaatgt agaaggaaaa ggacatagtg
    44341 tatctataca ttcaaataca gttaaaaata tagaatatgc aggagaaaat atagaagtat
    44401 caagatttgt tattaatcaa tgttgtgcta ctagtgctgg aggaagtttc tttaatggtc
    44461 ttgcacctac taatactcta ggttgtggtt cttggggaaa taacagcatc tctgaaaatc
    44521 ttgattataa gcatctaatt aatatttcta gaattgctta ttatatgcca gaaaatgaag
    44581 tccctacaga tgaagaactt tggggataaa atttagacaa aaaatattca ttctaaatta
    44641 aagtaggaat atattttaat ttagaatgaa tttaagacat aaattaaatt taaattagtt
    44701 tattggacta aatttaaaat attaagagac atatagaaga aggaagtatt ataatttaaa
    44761 ataaataaaa aaatctataa aagagaagga gtggttttat tatggcatta atgacaggag
    44821 ctcaatatat tgaaagtttg agaaaattaa atactaaggt ttatatgttt ggtgaagagg
    44881 ttaagaattg ggttgaccat cctatgatta gaccatctat aaattgtgta gcagcaactt
    44941 atgacttagc tcatgaccca gaatatgcag atttaatgac agttacttca aatatcacag
    45001 gtgaaaaaat aaatagattt ggtcatcttc atcaaagtgt tgatgatttg ataaaaaaag
    45061 taaaaatgca aagactatgt ggtcaaaaaa cagcttcttg tttccaaaga tgtgttggta
    45121 tggatgcgtt taatgcagtg tattcaacaa catttgagtg tgataaagcc catggaacta
    45181 attatcatga taattttgta aaatacttaa cttatataca agaaaacgat ttagtagttg
    45241 atggagctat gactgaccct aagggagata gaagtctatc acctagtgct caacctgacc
    45301 cagatatgtt ccttcatata gtagaaagaa gagaagatgg gataattgta agaggagcaa
    45361 aggcacatca aactggttca ataaattcac atgagcacct tataatgcct actataagta
    45421 tgactgaagc agataaagac tacgctgtat catttgcagt tccttcagat gctgaaggag
    45481 tgtttatgat ttatggaaga caatcttgtg acactagaaa attagaagaa ggtgcagatg
    45541 ttgatttagg aaataaggag tttggaggtc aagaagcttt agtagtattt gataatgtat
    45601 ttgttccaaa tgatagaatt ttcttatgtg gagaatggga tttctctggt atgttagtag
    45661 agagatttgc aggataccat agacaaagtt atggtggatg taaagtagga gtaggtgatg
    45721 taataatagg agcagcagct ttagcagctg attataatgg agcaaacaaa gcttcacata
    45781 taaaagataa actaatagaa atgactcacc ttaatgaaag cttatattgc tgtggtatag
    45841 catgttcatc agaaggtcac aaaacagaag ctggaaacta tcaaatagat ttacttcttg
    45901 caaatgtgtg taaacaaaat gtaactagat ttccttatga aatagtaaga cttgcagaag
    45961 atatagctgg agggcttatg gttactatgc cttcagaaaa agactttaaa tcagacctta
    46021 aagttggaac aagtggaatg actattggcg aagtatgtaa caagtatttt aaagcttctt
    46081 cagtggcttc aacagaagaa agaatgagaa tattaagatt cttagaaaat atatgccttg
    46141 gttcatctgc tgttggttat agaactgagt caatgcatgg ggcaggttca ccacaagctc
    46201 aaagaataat gatttcaaga caaggaaaca taaatcaaaa gaaagaatta gctaagaaaa
    46261 ttgcgggaat aaaaaaagag gaagctttaa atttataaaa agttgatata taaagggaaa
    46321 ttatatatta atgtgtatta attaatgaaa aaatatgtag tataagagat agttataaaa
    46381 ttatggtggt ttttagctaa gtaaagaaat ttttaataag gagaatttac acatgacctg
    46441 tggagttaga ttttgtgggg gctgtaaccc tagatacgaa agagggaagg ctcttacaat
    46501 aatcaaagag cacttcaatg gtagggtaga ttttagtata gcacaagaga acatcgagta
    46561 tgatttgcta cttataattg gaggatgcgc aactctatgc gcatcctatc aacaatataa
    46621 agtgaaaaat gaatgtgtta agatgtggga ttttagccat atagaaagag ttataaatgt
    46681 gattgaatca gcaatttgtg aaacttaaaa aagctaaatg gggggatttc attgagttgg
    46741 caagaattgt atcaaagtaa attatgtagt gctacagaag ctgtaaaaca gattaaaaac
    46801 ggtgatactg tagtatttgc acattgtgta ggtgaacctc ctgcactagt agaggctatg
    46861 attgaaaatg ctgaacaata taaagatgtt gagattaaac atatggtaag cttgggtagt
    46921 ggtggatata ctgctaaggg aatggaagct cattttagag taaatccaat gtttgtaagt
    46981 ggaaatgtaa gaaaggcaat tgaaaatgga gatggtgatt ttacacctgc attcttccat
    47041 gaagtaccaa agttgcttag agaaaaaaga ttaaaatgtg atgttgtttt agcacaggta
    47101 actccaccag atgaacatgg gtattgtagc ttaggaacat cagttgatta tacttatgaa
    47161 gccattaaaa ctgctagaac agtaattgtt caagtgaatg accagtttcc tagaacctat
    47221 ggtgaggtag tccatgtatc agagtttgac tatatagtgg aaaaatcaca acctttattt
    47281 gagctacaac ctgcaaagat tggagaagta gaagaagcaa ttggtaaaaa ttgtgcttca
    47341 ttaattgaag atggttctac tttacagcta gggattggtg ggataccaga tgcagttatg
    47401 ttatttttaa ctgataaaaa ggatttaggg attcattcag aaatgatttc agatgggact
    47461 ttggcccttt atgaaaaagg tgttataaat ggtaaatata aaaattttga taaagaaaaa
    47521 atgacagtta ccttcttaat gggtactaaa aaattatatg actttgcaaa taataaccct
    47581 gcagtagagg taaaaccagt agactatgtg aatcatccag caattataat gaaacaacat
    47641 aagatggttt ctataaattc tgctatacaa gttgatttaa tgggacaggt agttgcagag
    47701 gctatgggac ttagacaatt tagtggtgtt ggaggtcaag ttgactttat acgtggagtg
    47761 tctatgggtg aagatggaaa ggcaattata gctatgcctt caataactac aaaaaaagat
    47821 ggtacagtaa tttcaaaaat cgtatctatt gtggatgaag gtgcacctat aacgacatca
    47881 agaaatgatg ttgactatat tgtaacagaa tacggtatag cagaattaaa aggaaaatct
    47941 cttagagaaa gagcaagaaa tttaataaat atagctcatc caagtgtaag agaacatcta
    48001 gcagtagaat ttgaaaagag atttaaggag aaatattaat aatagagggg tgttaataat
    48061 ggaagcactt agagtagttc caaagatatt ttactttgat acatttaaag aatttaatga
    48121 agaatttaaa ataggaaaaa atgatttagt aattactaat gagtttatat atgagccata
    48181 tatgaaacct cttggaatag atacaaattt aatttttcaa gaaaagtttg gaacaggtga
    48241 accatctgat gaaatgatag actccatgac aaaggaaatg aagaaataca attttgatag
    48301 aattattgca tttggaggag gaacaatagt tgatatatgt aagatattag cacttgatgt
    48361 tccagaaaag tctattgatt tatttgaagg agaagtatca cctaaaaaag taaaagagtt
    48421 agtagtagtt cctacaacat gtggtacagg tagtgaagta acaaatgtag ctattgcaga
    48481 gttaaaatct aaacatacta aaaaggggct tgcagtagaa gaaacatatg cagactatgc
    48541 agtgttaatt ccagagacag taaaagggtt accttacaaa ttctttgtta caagttcggt
    48601 agatgctctt atacatgcta ttgagtctta tctttctcca aaagcaagtc catttacaga
    48661 gatgtattct ctacaagcaa taaaaatgat tatggatggg tataagaaga tagttgataa
    48721 aggagaagaa gagagattta atcatcttag agactttgta cttgcatcaa attatgcagg
    48781 aattgctttt ggaaatgctg gttgtgcagc agttcatgca ctatcttatt caataggtgg
    48841 agctttccat gttgcacatg gtgaagcaaa ttatcagttc tttactgaag tatttaagat
    48901 gtattctaga aaaaaaccta atggaaaaat tataaaatgt acaaaaattt tagcagatgc
    48961 ccttgaatgt gaccctaact gtgatgttta tggagaatta gaaaagtttt taaataaatt
    49021 aatagctaaa aaagctttga gagaatatgg aatggtggaa agtcagatag atgaatttac
    49081 agatagtaca atagcaaatc aacaacgact acttgctaat aattatgtag agcttagtag
    49141 agaggaaata agagagatat ttgcaaatct ttattaatac aattttttat ttatatgtat
    49201 agtcaacata aacaatgcta attatattta tgtacaaata aaaataaggg aacttaaatt
    49261 ttaattaaag ttaagttctc ttatttttat atggagttaa atataagtat atttttaatt
    49321 taaaatatgc ttatatttaa gtctattact ttatttgaaa caatttgtag aatttcaaat
    49381 tccttgacag taataagtaa gtaattgtat aatcaaactg caatatatta ataatattag
    49441 tgaaaatgaa aggattataa aatatgtata aatcagaaaa tttttcaaaa aaatctgtat
    49501 taataaattc atttttaagt aaatttttaa aaataattgg atggggtttg gtaagcttat
    49561 ttacattatc agccttagta ctttcaacta tttccattat aattggatgg gctgtaatac
    49621 ttcatattca agtatgtgca gtatttttac ttataggagg agtttgtatt tttaaaggta
    49681 agagattagg agaccaaatt tctcgttata aaaaatattg tacaattata aacaatagaa
    49741 atattattcc agtagaactt attgcagaaa acacatctaa atcattaaat tttataataa
    49801 aagatgtaca aaagatgata gacaaaaact actttataaa tacttatatt gataaaagaa
    49861 ataatcagat tgtgttaaca aatgaagatt ttgttccacc aagatatgaa gatgtagcat
    49921 atgaagtcaa agaagaagaa aagactgatg aatccaatga agttgataca attataaata
    49981 aaggaatgaa ttatctaaca caaataaaag aagctaataa aaatattaaa tcagaatcaa
    50041 tgggcgataa aattgtacaa gtagaagatg ttacaagtaa aatatttgat gttgtaaaac
    50101 atgacccatc aaaacttact caaatacaaa aatttatgga ttattatctt ccaaccactt
    50161 taaaactatt aaattcatat catacattgg aagaacaagg aattgataga gaaaatataa
    50221 caacaactat ggaaagtatt gaaaatacaa tgaatacgat tgtagtagct tttgaaaatc
    50281 aattggacta tctgtttgaa gatgaagcca ttgatatttc tacagatatt actgttttag
    50341 agaatatgtt agtccaagaa ggattaacga gtggtaaatt ttaacttcaa tagaaaaaat
    50401 attctgttat ttttaaacaa ttaattagtc ataaagtata aaatgtgtat tatataagtt
    50461 aatcagtact ttatgaagga agaggagaga aagatacaat gaataattta gatgatatac
    50521 cagttatgcc aactttgaca cttgacccat ttggagaaga atcaaacact aatgatatag
    50581 ataattctga cttattaatg aaaaaggatg aaaaagaccc agaagaagaa aaactgtctg
    50641 aatctgaacg caagatggta aaggaatttg cggaaaaaat agatattaca aatacaaata
    50701 tgattttgca atatggagct ggtgctcaaa aaaaggtagc aagtttttct gaaacagctt
    50761 taaagagtgt aaagacaaga gatttaggag aagttggaga tatgcttaca aatctagtta
    50821 ctgatttaaa agcattttca gcagatgaaa aagaacaaag tggtttttta ggaattttta
    50881 aaaaggcaaa taataaaatt tcaaatttaa aaactaagta tgatagtgca gaggtaaatg
    50941 tggataaagt aagcaaagag cttcaaaagc atcaggttaa aatattgaaa gatatagcaa
    51001 tgcttgataa gatgtatgaa ttgaacttag cttactcaaa agagcttact atgtatatta
    51061 tagcaggaaa acaaaaatta aaggatatga aagaatatga gatgccaaag ttgagagaaa
    51121 aagctcgttt atctggttca acagaagatg ctcaatctgt aaatgatatg gtttcacttt
    51181 gtgacagatt tgaaaagaag attcatgact tagaattaac tagaatggta tcgcttcaaa
    51241 tggctcctca gataagattg gttcaaaata gtaataatct gatggcagaa aagattcaat
    51301 caactatagt aaataccatt ccattatgga aaaatcaaat agtgcttgct cttggaattt
    51361 ctcacttaaa tcaagctatg aaagcacagc gtgaagttag taatatgaca aatgagcttt
    51421 tattaaagaa tgcagaaact ttgaagatgg gaacaataga aacagcaaaa gaatcagaaa
    51481 gaggaattgt agatatagac acaattaaga aaactaatca atctctaata tctactattg
    51541 atgaggtagt taaaatacaa catgatggta gaataaagag acaagaagca gaagttgaat
    51601 tatcaaaaat agaaaatgaa cttaaaagta agcttcttga atttacagtt aaataaaaat
    51661 tatactaata taaaaagaga ctgtctcaaa atagagataa gtctcttttt cattgtttaa
    51721 atgattaaag tatatttata ttataaattt ctattatctt ttaacataac atcatgagct
    51781 ccaccttcaa ctatactagt agaagataca agtgtaagtt tagcattttt ttgaagttca
    51841 ggaatgctaa gtgctccaca gttacacata gtagaacgaa ctttacttaa agaaagagtt
    51901 acattgtctt tcaaagaacc agcataaggc acataagagt caacaccttc ttcaaaagaa
    51961 agtttcttat ctccaccaag gtcatatctt tgccagtttc tagcacgagc agaaccttct
    52021 ccccaatact ctttcatata actaccattt atattaactt tgttagttgg actctcatca
    52081 aaacgagaga agtatctacc aagcattata aaatctgcac ccatagctaa agctaaagtt
    52141 atatgatggt cataaacgat accaccatca gagcaaattg gaatataaat acctgttttt
    52201 tcaaagtatt cgtctctagc ttgagcaact tcaattatag aagtagcttg tccacgtcct
    52261 ataccttttt gttcacgagt tatacatata gaaccaccac caataccaac tttaacgaaa
    52321 tcagcaccag cttcagctag gtaaaggaat ccttcgcggt caactacatt tccagctcct
    52381 accttaactg tatcaccata tttttcacga atgaaatcaa gtgttatttt ttgccactca
    52441 gaaaaacctt ctgaagaatc tatacataaa acatcagcac cagcttcaac taaagcagga
    52501 acacgttcag caaagtctct agtattaata ccagctccaa ctacatatct cttagaagaa
    52561 tctaaaagtt caagtggatt ttctttatga gaagagtaat ctttacggaa taccatatac
    52621 ataagattac cattatcatc aagcacagga agagaattaa gtttgtggtc ccatataatg
    52681 ttgtttgctt cctttaaagt aacatctttg ttagcataaa ctatagatga cataggagtc
    52741 ataaattcac taactttagt atctaaatcc atacgactta tacgataatc acgacttgca
    52801 acaataccca ataatttacc agttgaagtt ccatcttcag taacagctac tgtagaatgt
    52861 ccagtttttt cttttaagtc aagtatgtct tttaatgtgt tatcaggttt aatatttgaa
    52921 tcacttacaa caaaaccagc tttgtgggat ttaacacgtg ctaccatagc agcttcattt
    52981 tcaatagttt gagaaccgta tataaatgaa ataccacctt ctttagcaag tgcaatagcc
    53041 attttgtcat cagaaacaga ttgcataata gcagaagtca aaggtatatt catataaata
    53101 tctgcttcct cgcccttttt aaatttagta acaggtgttt ttaaacttac attagcaggt
    53161 atacaatcag tagaagagaa acctggtaca agaaggtatt cactgaaagt atgtgatggt
    53221 gtatcaaaat aaaacgccat tttttaatca ctccttatat ttttatactt tttataattg
    53281 atagtattaa ttataactta ttctttaatt ttattaaagt attttgtcaa atattgagat
    53341 ttttgaaaaa tttaaactat tttaattaaa tttgtttaat atatattgcc ttatagggta
    53401 aagttgtata ttaaataatg tttagtgttt aatagtagct aatttaaaat taatctttag
    53461 tgattcatat aattacattt gtatagttta cattgataat attactagag agtgtataaa
    53521 cctcaaaaat acagataaat taaatctata ttagtatatc caaaagtaca tttaataaat
    53581 ttatttaact gaattattat tttcatttct attaaattta aatattttat aaaaatagta
    53641 ttatttacaa aatcatatac tccaaaatac tacataaata aaattaaaca aaaactaaaa
    53701 tgacaaatgt cattatctaa agtgacatag aaacggtttc ttaaagttgt tactataaaa
    53761 tataaactct ataataaaag tataacaaaa gggaatcata tcgatataga atataattca
    53821 agaggaggta aaattatgag tagttctaat caatcgacaa taaagacatc tatacagcga
    53881 gtagggaaat ttttaagtgg tatggtaatg ccaaatatag gagcttttat agcatggggt
    53941 cttataacag cattatttat accaacagga tggatgccta atgaaaaatt gagtactata
    54001 ggtgacccaa tgataaaata ccttttacca ctattgatag cttatactgg tggtaaagca
    54061 atagcaggac aaagaggtgg cgtaataggt gcagcagcag ctatgggagt aattgttggt
    54121 gcagatatac caatgtttat cggagcaatg ataatgggac catttgcagg atgggtaatt
    54181 aagaagtttg ataaatttgt agatggaaag ataccaacag ggtttgaaat gttagtaaat
    54241 aacttttcaa taggtataat aggtatgctt cttgcaatac taggatttta tgcaattgga
    54301 ccagcaatag tagcagggac agctcttata gaatctggag ttcaatttat agttagcaaa
    54361 agtttattgc ctctagtttc agtatttata gaacctggaa aagtattatt cttaaacaat
    54421 gcaataaatc atggtatatt agggcctata ggtatagctg aggcaaaaga agcaggtaaa
    54481 tctataatgt tcttactaga aagtaaccct ggaccaggtt taggagttct attagcatat
    54541 tggatgttta gtagaggaag tgtaaaacaa tcagcaccag gagctgtaat aatacatttc
    54601 tttggtggta tccatgaaat ttacttccca tatattttaa tgaatccagt tttaatattg
    54661 gctacaatgg caggtggagc agcaggaata ttgacttttt caatattagg agctgggctt
    54721 gtagcagcac catcaccagg aagtatattt gcacttatgg cactagctcc aaagggagga
    54781 ttacttccag tattagcagg agttgcagtg gcaacagttg tatcattctt agtggcagca
    54841 ccatttgtta agagagcttc agcaaatcaa agtgaagaag acagtacttc tttagaagaa
    54901 gctaaagcaa aaatgagtga tatgaaatct gcaagtaaga actctgagaa aaatattgag
    54961 gaaaaacagc ttgaagtaaa tgagattaag aagattgtat ttgcatgtga tgcaggaatg
    55021 ggttcgagtg caatgggagc ttccagattt aaaaatagaa taaaaaactt agacttaaat
    55081 atagaaatta caaattcatc tgttgataat cttccagatg atacacaaat agtagtaact
    55141 cacaatacat tagttgaaag agttgctaag aataattcga gtgttgagat agtttcaata
    55201 aacaattttt taaatgaccc aaatttagat acattattta aaagattaga atctaaataa
    55261 aaataaaaag taccactaat taggagtgga taatttgaaa aaaaagaaga ttacatctag
    55321 gcaaaaaaag ataatactaa tgatagtaga aaattcaaag aaaaacattc caataactat
    55381 ttctgagatt gcagggactt tagagttaag ttcaagaact gtacttagag atatgtctgg
    55441 aattgaaaaa tggtttgatg aaaatgattt taactttgta aaaaaaccag gagtgggatt
    55501 gattttagag gaaaatatag aaaatcaaaa ctttataatt gagttgttag aagaagaaaa
    55561 aatagaaaaa gaatacagca aggaagaaag aaatttaatt atattatcaa agctactagt
    55621 ttctaacgag ccagtaaaat cctattattt tgcaaaaata ttaaaggtat ctgaaggggt
    55681 actgaataat gattttgcct tagcaagtaa atggttggaa agatttgata ttgagcttgt
    55741 tagaaaacca gggcttggtg tctatttaaa aggtcaagaa aaaagcttta gagaggcata
    55801 tgtaaatctt atatacgatt cattcaatga aaaagaaata ctagatatgg tcagaaatat
    55861 aagtgaaaat atacaaacag ataaagcaat agaaatttta agtgaaaata gacttttaaa
    55921 tttaatggac aggtgcataa taagaaaagt tgaagctaca ttaacaaaga agctttcaga
    55981 tttagatgta aatttagctg atagtgcata tatagggctt gtagttcata tttcattagc
    56041 cttacagagg ataaaaaatg gtgaaaatat aactatggat aaagagtttc taaaagaatt
    56101 atctataaca gaagagttta aattagctaa agaaatcgta aaaggtatgg aaacagattt
    56161 taacatggat ataccagtag atgaggttgg atatataact atgcatataa gaggtgcaaa
    56221 gcaaaggtca tcttcaaacc ataaggcttt aaacttagat gatatagaaa taatggaaat
    56281 tacaaataag atgatagatt tggcggaaga tgaatttaaa ataagtttaa aaaatgacga
    56341 gaggttattt aaagacctag caaatcactt agggccttct ataaataggt tgaatatggg
    56401 attagaaata agaaatcctc ttttagatga aataaaaagc aagtattcat atgcctatga
    56461 tggagttgaa aagatttcta gaattataaa agataaacta aatataaatt caatacctga
    56521 atcagaaata ggatatattg caatgcactt tgcatcagcc atagaaaaaa atcttatgat
    56581 gaatactaat ataaatattg ttgtggcatg tcccactgga ataggtactt caagattctt
    56641 atcaactaag attgaaaata aatttcctaa tttaaatata cttgaaacca tatcagctat
    56701 aaacatagat gaagagtatt taaaggaaaa agatgttgat ttaatagtgt ctacagttga
    56761 gttaaataca agtttaaatt atatatgtgt aggtccattt atgagtttag atgatgaaca
    56821 gataatcaag gaaaaaataa aatctatagc tcaaaataaa ttaatcaatt taaatgcgaa
    56881 aaatgatact aagagtaaga ataaagtata tgaacagata acagaaagta tgaatatagg
    56941 aaaagatatt cttcaatttt tagaggaaat tagatttgaa aaatttgaaa gtaaagattt
    57001 aagtgagctt attgaagact catcaaaaat atttgcaaaa tctagtgaag atataatctc
    57061 tataaaagaa tcgttaaaag aaagattaaa aatttcaatt ccatatatag aagaatcaaa
    57121 aattctattg ttacattgta tgagtgaaag aatagatatt atgaagttat caataataaa
    57181 actagagaat agaatcgtgc tagattcaaa tgaagaaatc gacaatgtag tttttatgtt
    57241 acttcctaaa aattcaccaa gttatcaaag acaaataatg agtgaaataa gtggttcatt
    57301 aatagacaat ataattttta ctaataagat aaataaattc tctatagaag agatggcatt
    57361 agaggtaaaa gatatagttt ttaattttta tacaaacaga ttaaaagcat ttatagataa
    57421 ataaaattaa tattaaaaag gaaggttgat actatgagta aagtattgaa tgagaataat
    57481 atatttttag ggttagatag tgtttcaaag gaagaagcta taactttagc aggaagaaaa
    57541 ttagttgaaa atggatatgt aaaagaagaa tatataccag caatgttaga aagagaaaaa
    57601 gtaatgacta catatatggg aatgggagtt gctattccac atggtgtaaa tgaagcaaaa
    57661 aaagaaatat tatcttctgg aatagttata ttacaattcc ctaatggtat agattttgat
    57721 ggagaaaaag catatttatt aataggaata gctggtgttg gagatgaaca tttagaaata
    57781 ctatctaata tagcagtagt tttagatgat gacttaacag aaagactaaa aaattcaaat
    57841 gacaaacaag cttttatgga agcttttgcc aactaatctt aggagggatt taaaatgaaa
    57901 aaggcaattc agtttggagc aggaaatatt ggaaggggtt ttattggagg cttgttagtt
    57961 aagtcgggtt atcatgtagt atttgctgat gtaaatgagg atatattaaa ctcaataaac
    58021 aaagataaaa agtatactat acacataaga gatgtagaat gtatagatga agtaattgat
    58081 aatataagtg cggtttcatc tataaaagaa gaaataatag atgagattgt acaggctgaa
    58141 ataataacta cagcagttgg acctttagtt ttgactaaaa tagcctctac aattgcaaaa
    58201 ggtataaagg ctagaaaaga aaagggatta acaagtaatc taaatataat agcatgtgaa
    58261 aatgcaatat acgcaagttc ttctttaaaa gaagaggtac ttaagtattt aaataaggaa
    58321 gaagtagaat atttagagat gtatgttggt tttccaaact gttcagttga tagaatagtt
    58381 cctcctggta aaaacgaaaa tcctcttgat gtaacagttg aaaattttta tgagtggaat
    58441 gttgaaaaac aaggatttaa aggggaaata ccaactatag ttggaatgaa tttagctgat
    58501 aatcttatgg cttatataga acgtaaattg tttacactga atacaggtca tgctataaca
    58561 gcttatatag gatatttaaa aggatataag actatagaag agagtataaa agataaattt
    58621 atctgtgata tagtcaaaag tgcaatggta gaaagtggag aaggattgat taaaaaatac
    58681 aattttgact cagaagtgca ctataaatat attgataaaa ttttaaatag atttaaaaat
    58741 ccatatctta atgatgatgt attaagagtc ggaagggaac cattaagaaa actaagtgat
    58801 aaagatagat tgattaaacc tttaatgaca gcaaaatcat atggattatc agttgataat
    58861 ttgattcttg gaataggtgc agcgcttcat tataataata gtgaagatac tcaaagtgta
    58921 gaattacaag agttgataaa gtctattggg gtaaaaaaag ccgttgctaa aatagctaat
    58981 ataagcaatg acgaagaact tttaaataat atcgaaaaaa gttatatatt tatgaaaaat
    59041 ttataaattt acttgaaaaa aagtagttct gataaagtaa ctataatata ttattctaca
    59101 cagtttgaat tatttgttga ataatagaga attataatat ataattaaaa ggaataaatt
    59161 aatatattta cctgtatatg tttgataata tggttcaaat gtttctacta agctaccatt
    59221 aatagcttga ctacaggagt gaagaagata tagtttatac ttattttaaa ttatatatta
    59281 agttaattac tttgaatttt aagctcctgt ctatgatata gacaggagct tttttagtat
    59341 tttaatataa aatacttaca agaatagata gcaaaattag aacaaatata atttttttat
    59401 taatataatt ttagaaaggg ctaggtggaa gttcaatgaa ggctttacaa gaaaagatat
    59461 tgagagaagg cagtgtttca ggaaatgata tactaaaagt tgatagtttt ttaaaccatc
    59521 aaattgatgt agctttttta aatgaaatag gaagagaatt taaagagaga tttaaaggag
    59581 aaaaggtgga taagatattt acaatagagg cttcaggaat agctatagca tcaattgttt
    59641 cacagtattt tgataatgca cctgtagtat ttgcaaaaaa atcagaatct aaaaatttgg
    59701 ataaagatgt atatgaaact aatgtatatt catttactaa ggcaagagag tattcagtta
    59761 aagtttctaa aaagtacata aacaaaggcg aaaatatatt gatagtggat gattttttgg
    59821 caaatggaag agctgctctt ggacttaaag atttaattga gcaagcagaa gctaacttag
    59881 ttggagtagg aattgtcatt gaaaaaggat ttcaagctgg aggagcactt ttaaaggcta
    59941 atgatgtaag attagagtct ttggcagtag ttgaatctat agataatgga actgtaaaat
    60001 ttaggtaatt tatgatatta tatacttgtg tttagcacat attttaacta tgtaattatg
    60061 gaggattttt tatgagattt tttatagaca cagccaatat tgaagaaata aaagaagcaa
    60121 atgatttagg tgtaatctgt ggtgtaacta ctaatccgtc tctaatagct aaagaaggta
    60181 gagattttat agaggtagtt aaagaaataa gtgaaatagt agatggacca ataagtgcag
    60241 aagtaataag tttagaacat aaaggtatga tagaggaagc agaaaaatta tctaagatac
    60301 ataaaaatat agttataaag atacctatga cagcagaagg tctaaaagcg gtgaaagtac
    60361 tatcaagtaa aggtataaag actaatgtaa cgcttatatt ctctgctgga caagctcttt
    60421 tagctgctag agctggagct acatatgtaa gtccttttgt tggtagattg gatgatatat
    60481 cacaaaatgg tcttgattta attgaagaaa tcgttgatat atttagtgta aatagtattg
    60541 aggctcaaat aatagttgct agtgttagaa atccaataca tgttttacaa gctgctagaa
    60601 tgggagcaga tatagcaaca gttcctctta aagttataaa ccaaatgatt aagcatcctt
    60661 tgacagacaa aggaatagat agctttatga aggattggga aggtgcttct ttaaaattat
    60721 aattataaac tacgctttat aagtatatta aagaggttat tatggaaatt ctaagtaata
    60781 aggctaggct attttgccta gtcttatttt ggtgtataat atattgaaac atattattga
    60841 aatagattaa ttttttaagt gaggaggcga aaaatggata aaatattaag agagatacaa
    60901 agagaagata aaaaaaatcc atatactgac caagaacttg ctgaaatgtt aaatgtagct
    60961 aggtctgaag tgatatcagt taggaaaaaa aataatattt tagattcgag agaaagaaga
    61021 aaaaaaatat taataaaaga tatatcaaaa attgtaagtg aaaatcctca aatgtctgaa
    61081 agaaaaataa ctgaaatatt aatagaaaat ggatataata tatcgagaag tgcagtttca
    61141 aaattattaa aagaggaaaa tttaaatcag tcaaagattg ggattaagga taaagaccca
    61201 gcatcatcag gaaagtatgt gaaggtgagt aaagttgtag aagaagatgg atttgaagaa
    61261 ttgataggta taaagggaag tttgaaagaa aaggtaaatt tagctaagtc agcaataatg
    61321 tatcctccta atggccttca tactataata tatggagaaa caggagtagg taaaagtgaa
    61381 ttagctacat gtatgtataa atatgctata aaaaataaca ttaaagaaga gaacagccca
    61441 tttatagtgt ttaactgtgc agactatgca gaaaatccta atctattgat agctcaactc
    61501 tttggggtag taaaaggtgc atatacagga gcagatgcaa atagagaagg tcttgtagaa
    61561 caagctaata atggaatatt gtttttagat gaaattcata gattgcctgc tgctgggcaa
    61621 gaaatcttat tttcattaat agatagagga gaatttagaa ggttaggaga aagtagttct
    61681 aatagaaagg caaatgttct cataataagt gctacaacag aaaatccaga ttctaattta
    61741 cttcaaacat ttagaagacg tataccaatg gtaataaatt tacctaatat gagtgaaaga
    61801 ccaaaatctg aaagatatga aataataata aagttttttg aaagagaagc aaagcgagta
    61861 aacaagaatt ttataataac taaagaagtt atgtgtgcac ttatgaatta taagtgtact
    61921 ggaaatatag gtcagttaaa gagtgatata caagtaactt gtgctagagc ttttagtaaa
    61981 tcgatatttt ctagcgataa ggtaattata gatttagata gtttaaggga ttatataaaa
    62041 agtggatatt atgattgtaa ttgtaaaaat gaaaagtatt ctgagttttc agttgaggat
    62101 atatatatag atattagtga attggtgagt ggaaaaaata gaattttatc tgataatgag
    62161 ataagtgaga tatataatta tgcagaaaaa gagcttaagg ttttggaaag taagtgcttt
    62221 tcagaagaag agttaaaaaa tgcatttata gaaaagttag ataagaagtt taatgctatt
    62281 aaaaacaata aaaatttatc tgatagaaga agtcgaatag actggggagg acaattaaaa
    62341 gagtctacac tggagataat ggataaggta attgtattta ttaaggagca gtttaagcat
    62401 gtaaatcaag gtctgtactt ggctctagca attcatattg agcatgctat aggtaggata
    62461 aaagatggaa aaactataat aaatccgagt ttagataaaa taaaagcatc aatgccaatg
    62521 gaatatgagt tgtcaagata tataatgggt atagtagaag atttgacaca agtaacattt
    62581 ccagaagatg agcttggata tttggcttat tatataaata aattttgtta taatgaggaa
    62641 agtataaaag ataaagttaa agtagtaata gttacgcatg gtaaagttgg aattgaaatg
    62701 tctaaagttg taaatcatat tttaggtata gaatgtacac taggtataga aatagcactt
    62761 acagattcac catcagaggg gatagagcat gtattagaag agcttcaaaa gatagaagct
    62821 agaaaaggta ttctagttct aattgatatg ggttctttgg taattcttgg tgatgaggtt
    62881 gaaaaaaggc ttggaattag atgtaaaact gtaaatagag tagatacatt attggcaatg
    62941 gaagcaggaa aacttgcaac tattgaagga aaaagtttag atggtataat agctgattta
    63001 aagaaaaata agaattatgc tatgataaat acaaataaat ttagttacag aaaaaacgag
    63061 tatggaaaga aaaatgtaat cattacttta tgtttgagtg gtttaggtac agctttaaat
    63121 ttaaaagagc atatagaaaa acaaattaag gaatatgaca ctttaattga agtaaagcca
    63181 gttgcttttt taaataataa tttagaagaa gagttaaatg atattgaagc tgaatataat
    63241 attattgcta tctgtggaac tattgatata gattataaaa acgtgccttt tatttcttat
    63301 aatgaggtac ttggtaaaaa tggtattaat aaagtattag agcatttaaa tagtaaacaa
    63361 ccagctttaa atattgaaaa ccagttgaat aatttaatac atgaagattt gattttatac
    63421 aattttgaag gaatttcaaa ggagtatata attgatactc ttgtttcaaa acttgaagaa
    63481 ggtggatatg ttgactcaaa gtatatatta agtgtatata aaagagaagc aatgggaagt
    63541 gttgtaatgg cctctaaggt agccgtgcca catggacttc cagaaaacgt tataaagcct
    63601 gcaatagcaa tcgcgaggtt gaataaacct atagtatggg acaataaatt tatggtggat
    63661 ttggtggtac tactggcact taaagaaaat aataagaaag aaatacgaag cttattttca
    63721 aagattaatg accagcatac tttagaagtt ttattaaata ctgaagataa aaatgaaata
    63781 aaagaacttt taagctaatt attagtaccg agaagaaaga caaaaaaatt tgctttagta
    63841 taaaatttaa aactactcaa ttgctaagta gttaattact ctatataagg ctagttctat
    63901 gaaatttatt tatatgattt tatagaatta gcttttttct tggtaaataa aatatatgaa
    63961 tttatttatg taaaaagtaa attttattgg acaattctat gagaattttt cctatatttc
    64021 ttataaaata tagaatatgt aaaaaatata taaaaataaa ttaaattcat aataaataat
    64081 tttataaaat agttgttaaa cataaaaaac catttgtaaa aaacaaaaaa atcatttctc
    64141 taacaaaaaa aaccacaaaa aatataaaaa agtatggcta gttaagtgat taacaagtaa
    64201 aaattaaaat aaaaatcaaa aaaaatttat caatgaaagt tagctaaaat cctggaagag
    64261 agcattattt ttgggaaaac attttctttt gtttcacaaa aaaagccact ttttggcaca
    64321 caacatgctt tatataaagt caagaaaaac taaggtataa gacaaaggca attaggaggt
    64381 gtaaatatgg agtttataaa ttttgtaagt gataaagtta tagaccttaa aatggattgt
    64441 aaaacgaaag aagatttctt taaagaaata cataataaag tttttgattt aggctttgta
    64501 aaagaagaat ttggagaaaa aatattagca agagaaaatg tatttccaac aggtttaaat
    64561 ttaggtgatt atggagtagc aataccacat acagatgcag aatatattaa agagcaattt
    64621 atatcagtct gtacttttaa tgaaccagta gtatttagtt ctatggaaga ccaagatgaa
    64681 aaagtacctg taaatttggc tttcgtatta ggacttaatc aaccacacag tcaattatct
    64741 gtattaacag aattaatggc aattatgcaa aataaagagt tagttgataa gttgatgagt
    64801 tctactgata aagaagaagt tttaaagaca ctaaagtctt tataaaaata aaaaagtact
    64861 aaaaataaaa aatataaaaa taaaaattat taggaggaaa taaaaatgaa aaaaatatta
    64921 gtagcatgtg gagcaggaat agcaacatca acagtagttt gtgacaaggt agagagatta
    64981 gttaaggaaa ataatataca agcagaagtt atacaatgca aaatagctga atgtgcaaca
    65041 aagcaagaag gagcagattt aatagtatca acaactatac taccaacaac ttataatata
    65101 ccagcaataa aagcaacagc atatataact ggagtaaata cagcagcatt agataaaaaa
    65161 atattagatg ctttaaaata atcctatcat agatacattg aaataatatt ttataaaaca
    65221 gaaaaaggag gatttataaa tggataaatt attagcagta gtacaataca ttttaaatat
    65281 gggaccgaca gtaatactac caataacaat tgtagtacta ggaatgatat ttagaattaa
    65341 gtttacaaaa gctttaaagt caggtcttac aattggtata ggatttgtgg gtataaactt
    65401 agttgtaaac ctattaacat caacactagg gccagcggct caaggaatgg ttgaaagatt
    65461 cggacttaat ttaacagtaa tagatgttgg ttggccaaca acagcatcag caacatgggc
    65521 ttcaccagtt gcaccaatat taataccagt ttgtttatta gtaaacttac tattattata
    65581 cttcaataaa acaaagatat taaacgttga tatatggaat tattggcact ttatagtagc
    65641 aggtgcagtt ggatatatag taacaggaag ttatgtttgg gctatattct gtgcaatact
    65701 aatggagtta ttagtactgt ttattgcaga aaagacagca aaaaatgttc aggagtttta
    65761 tgatttagaa ggtatagcat taccaactgg ttcaacagct tcatttgctc cacttggata
    65821 tttagtaggt aaatttgttg aaaaaatacc aggaataaat aaaatacaag cagacccaga
    65881 ctctatacaa aaaagatttg gtatatttgg agaaccaatg atgatgggga ttatactagg
    65941 tataatactt ggagcacttg cgggatatga tgtagcagga atattcaatg taggtatatc
    66001 aatgggtgca gtaatgttac ttatgcctag aatggttaga atattaatgg aaggtttaat
    66061 tccaatttca gaatcaataa gagatttctt acaagcaaaa tatggagaca gagaacttta
    66121 tataggtctg gatgcagcag tagcaactgg acatccagca gttatatcaa cagctcttat
    66181 acttgttcct ataactttgt tcttagcagt tatactacca ggaaacaaag ttttaccatt
    66241 tggagactta gcgacaatac cattttatat ggcatttata gtgtgtttta gaaaaggtaa
    66301 tatagttcaa tcagttataa caggaacaat agtaatagct atatcacttt atatggctac
    66361 aaactttgca gatgttcata cacaattatt acaacaagca aatatgatgc cagaaggaac
    66421 aacaatggtt acaagtatag atacaggtgg aaacttgcta aaatggggaa tattgaaatt
    66481 atctcaatta gtttcttcat ttggaatatt ctagtatgta gttaatagag attactcttt
    66541 tttagtaaag tatgcgaaaa tttaacattt agcagctact aaaaaagagt aatatttttt
    66601 ataaattttt aaaaatacaa aatacaagag gaggagattt atcgtgaaag cagcagtatt
    66661 acatggcaca aatgatatga gatttgaaga tatagaaata aaaccatgtg aaagtgatga
    66721 agtaaaaata aaagttatgg cagcaggaat atgtgggtca gatcctccaa gagtattaaa
    66781 acattggaaa tatccagttc cagctatacc aggacatgag ttttctggag taattgctga
    66841 agttggtaag gatgtaaaaa atgtaaaagt tggagataga gtagttgcaa ttccttttat
    66901 accttgtaat gaatgtgaat attgtaaaag aggattattt tcattgtgtg ataaccatgg
    66961 aatgttagga gctaaaagtt ttggagcttt tgcagagtat gtaaatataa aagctacaaa
    67021 tgtacttcca ataggagata tgaactttga agatgctgca atgatagagc cactagcagt
    67081 tgctatgcat ggagtactta atataggtgt tcaagttgga gacactgtag ctgtaatggg
    67141 tagtggaaca atggggcagt tggtaataca aggacttaaa atagcagggg caggaacaat
    67201 tatagcagtt gatatatctg ataataaatt aagagaatca aaggaattag gggctgatat
    67261 aataattaat gctaaagata ctaacccagt agaaaaaata aaagaactta ctggtggaaa
    67321 aggtgttgac atagctcttg aatgtgcagg ttcaaaaata actcaagaac aatgtttact
    67381 tataactaaa aagaaaagta agataggatt tttagggata gcatattcag atataacttt
    67441 atcagaagaa gcatttgaaa atatatttag aaaagaacta gaattaaaag gtttttggaa
    67501 ctcttattct gcaccatttc caggacaaga atggactaag ggaatcaatc tagttaatga
    67561 aggaaagata aaattaaaag aaatggtatc tcatagattc tcacttgaag atacttacaa
    67621 agcatttgaa atgataagag atagaaaaga agaatttaac aaaatattaa ttttaccaca
    67681 aggggttgaa aaataatgaa agcagtagtt aaaactaaac caggctatga taatgtagaa
    67741 gttttagaag tagaagaacc aaaagctaca ggagacaagg ttaaaataaa agtagaatat
    67801 agtggtatat gtggttcaga tatacattca tttaaaggtg aatatgcaaa tataaaagcc
    67861 ccagtaacat taggtcatga attttctgga attgttgtag aagtaggaga agatgttaaa
    67921 aatataaaag taggagatag agttacatca gagactactt ttgcaacttg tgagaaatgt
    67981 atatattgtg aaactaaaga ttataactta tgcccaacta gaaaaggtat tggtactcaa
    68041 gtaaatggaa gttttgctga gtatgtatta tcaagagaag aaagcataca tgtacttcct
    68101 gaaaatgtat ctttattatc agcagccctt acagagccac tagcttgttg tgttcatgca
    68161 gctcttgaaa agactactat agaaagttct gatacagttt taataatagg accaggacca
    68221 attggtttat tattagctca agttgttaaa tctcaaggta ctacagttat aatgtctggt
    68281 gttacaaaag ataaggaaag attagaaata gctaaaaatc ttggagtaga tagaactgta
    68341 aatgtaatgg aagaaagttt ggcagatgta gtgaatgaaa tgactgatgg aaatggagta
    68401 aacaaaggat ttgattgttc tgggtttatg ccagcagtta acgaagcctt aagactgctt
    68461 agaaaaaaag gtactttcgt acaagttgga atctttgcta aaaaattaaa tgaaatggac
    68521 caagaagcaa taatccaaag agagttacaa tatataggaa gcaggtctca aaagccaagt
    68581 tcttggatta cagcattaga tttaatggca aatgggaaag taaatacaga agctttagtt
    68641 actagaactg ttggtttaga cgaatttaaa gaaggtatta cagctttaat gaacggggaa
    68701 gaaataaaag tagcagtaaa atcttaaaaa aacatttgta ttattttaaa aaaaattgta
    68761 aaatctactg taggataaaa aaatgtaagg tcttaaaaaa taacaggagg aagaaagtat
    68821 gagcactctt agagatcatt ctaataatat tagaaaaaac ataataaaaa tggttgcaga
    68881 agctaaaagc ggacatccag gtggttcatt atcaatagct gatatgttga cagtattata
    68941 ttttgataag atgaacgtat gtgcagaaaa tccaaaaatg gctgatagag atagatttgt
    69001 tctatcaaaa ggtcatgcag caccagcttt atatgctaca ttagcagaaa aaggattttt
    69061 cccagaagaa gaattaataa cactaagaaa atttggttct aagttacaag gtcacccaga
    69121 catgaaaaaa gtagcaggaa tcgatatgtc tactggttct cttggtcaag ggctatctgc
    69181 agcaaatggt atggcacttg caggaaaatt agataacaaa gactatacag tatatactat
    69241 attaggtgat ggagaaatcc aagaaggtca aatatgggaa gctgcaatga cagcatcaca
    69301 ttacaaatta gataatttaa ttgcatttgt tgacttaaat ggattacaaa tagatggttc
    69361 taatgaagaa gtaatgaatg taaatccagt agatgacaaa ttcaaatctt ttggatggaa
    69421 tgtaatagta ataaatggac attcttttga agaaatagga aatgcagttg atgaagctaa
    69481 aaaagttaca ggaaaaccaa ctgtaataat agctaaaaca gtaaaaggta aaggtgtttc
    69541 atttatggaa aataatgctg catggcatgg aacagctcca aatgcagaac aagcagagca
    69601 agcattgaaa gatttagaag gaggtctata ggaatgggaa tagcaactag agaagcttac
    69661 ggacaagtgt taaaagaact tgcagaaaat aaagatatag tagtattaga tgcagattta
    69721 ggaaaagcta caaaaagtat atcatttaaa gaagttgccc cagatagatt ttttgacatg
    69781 gggatagcag aaggtgacat gattggtaca gcagcaggtc ttgctacttg tggaaaaata
    69841 ccttttgcga gtacttttgc aatatttgca gcaggaagag gctatgagca aataagaaac
    69901 tctgtagcat atccaaattt aaatgtaaaa atagcagcta ctcatgcagg tgtaacagta
    69961 ggtgaagatg gtggtagcca tcaagctata gaggatatat ctctaatgag aggtatacca
    70021 aatatggttg tattaaatcc agcagatgct ttagaagcaa gacaagctat tcttgcatct
    70081 attgattata atggacctgt ttatataaga ttaggtagag ctgcaactcc tgatgtaaac
    70141 agtgaaaatt ataaatttga aataggaaaa ggaactgttt taagagaagg ttctgacata
    70201 acagtaatag ctacaggaat aatggtagca aaagccttag aagcagcaga agaacttgct
    70261 aaagaaggta taaatgtaga agttgttaat atatctacaa taaaaccatt agatgaagca
    70321 ttaataaaag aaactgctaa gaaaactgga aaagtagtta cagcagagga gcacagtata
    70381 ataggtggtt taggttcagc tgtatgtgaa gctttagcag aaactaaaga tgtagtagtt
    70441 agaagaattg gtgttaaaga tgtatttggt caatcaggta caccagctga tttattaaaa
    70501 cactatggtt taactacaga agatatagta aaaaatataa aagagttatt atagatataa
    70561 atatatctaa ataacaaatt gatttgacat aagtcaatta aagctgtctt aaaaatagaa
    70621 agaaatttct acaatgggac agctttattt ttacaatact ttatttttat gataattata
    70681 aaatagtctg aaagtaatca aaaaaattat aaaaagaggt gctatttaat gaaaatatct
    70741 attggatgtg accatggtgg ttatgaatta aaggaatata taaaggaaaa tttaataaat
    70801 aaaggtatag aagttgaaga tgtgggtaca aattcaaaag aaagtgtaga ttttccaata
    70861 tatgcaaaaa aggtaagtca aaatgttcaa agtaaaaaat ctgatttagg catactttgt
    70921 tgtggaacag gaataggtat gtctattgca gcaaataagt ttaaaggaat cagagcagct
    70981 gttgtttctg actgtttttc agctaaggca actagagaac acaataatac aaatgtactt
    71041 tgtttaggag aaagagttat tgggaaagga ttagcaatga gaattgttga agaatggtta
    71101 aattcaagtt ataatggaga aagacatgca agaagattgc aaatgattga tgatatagaa
    71161 aaagaaaatt tataaatata taatttataa caagggggag cgttatgtct attatttgtg
    71221 cttcaataat gtgtgcagac caaatgaagt taaaagagga attagaagct cttgaagaag
    71281 caggtgtaaa attacttcat tgtgatgtta tggatggaat atttgttaaa aacttggcta
    71341 tgggaccaga gttattaaaa tcaataagtg aaaatacaac aataccttta gacatacact
    71401 tagccacaga aactccagat aaatatattg atatgatgtc ttatataaag ccaaaatata
    71461 tttcttttca tgtagaatca agtacaaatg taaaagctga tatacaaaag ttaagaaatt
    71521 atggtatagg gccagtgtta gcaataagcc ctcaaacaag tgtggataaa atagaagaat
    71581 atataagttt agttgagggt atcttagtaa tgacagtaaa tccagggttt gcaggtcaaa
    71641 agtttaatct ttctgtattg gataagttgg ataaacttac agagatacta aaagattatg
    71701 ataatcctcc atttatagag gttgatggaa atataaataa ggatactatt aaacttatga
    71761 atggtaaaaa agtagatata tatgttgttg gtacttcagc tttatttaat gataagcctc
    71821 caatttcata taaagataaa atagaagaac taaaagaaag tataaagtaa ccatgtaata
    71881 aaattataat atgtttctgt ttaatagtaa aaatttaggt ggaaacaaga aattttataa
    71941 tatttaataa aaattttggt tgagtaagga gaatttttta tgggagacct atataaacta
    72001 caaaatggta ctgatattag aggaatagcg tatgaaaatg attctaaaga agttaaccta
    72061 actgtagaag aagtaaaaaa aatagctaaa gcgtttcata tttggttaaa agaaaagact
    72121 aagaaagata aagtaactgt tgccatagga actgattcta ggataacagg aagccaattt
    72181 agaagtactg ttattgaaac tttaactaat gatgattgta atgtaattga ttgtgagatt
    72241 gccacaactc cagctatgtt tatgacaact attatggatg gatacaattc tgatggggcg
    72301 attatgatta cagcaagtca cttaccttat tactataatg gtttaaagtt tttcacagaa
    72361 agtggaggtt tagaaaaaac tgatataaaa gagatgttgg atatagctgt taaaaatgat
    72421 agtgtagact atgaggaagt aaataaaaaa ggtgaagtta tagtaaaaaa tttaatagaa
    72481 gattattcta atttattaat agataaaatt agaaaaggtg taaattcaag taaaaattat
    72541 gaaaagcctt tttctgggct taagatattg gttgatgcag gaaatggggc tggtggattc
    72601 tttgctgaaa aagttttaca catactggga gcagatacga caggtagtca gtttttgaac
    72661 ccagatggta tgttcccaaa tcatatacct aatcccgaaa acaaagaagc aatggaaagc
    72721 atatgtaaag ctgtgttaga taataagagc gacctaggaa taatctttga tacagatgta
    72781 gacagagctg ctattgtagg taaaaatggc aaaccaataa ataaaaatgc tcttatagct
    72841 gttatatcat caatagtatt agaagaacat ccaaaaacag ctatagtaac agattcgatt
    72901 acttctgaag gacttgctaa atttataaat gaattacaag gaagacatca tagatttaaa
    72961 agaggatata aaaatgtaat aaatgaagct ataagattaa atagtgaagg tgaagagtgc
    73021 catttagcta tagaaacgtc tggacatgct gctttaaaag aaaattattt cttagatgat
    73081 ggggcatatt taatagctaa aattttaata aaagtagcaa agctatcctt agaaggaaag
    73141 actatagaag aattgataga aaaccttgaa gaagctcaag aagagaaaga agttagaata
    73201 ggcattaata aagaagattt tagaccatat gcagaggata tattaaaaga tttagattct
    73261 catgtcaaga gtattgatgg atggtctgta gcaccaaata attttgaagg cataagagtt
    73321 aattgtgatg aatcaaatgg agatggatgg tttttactta gaatatcact acatgaacca
    73381 ttattagctt taaatattga atcaaataaa attggcggag cagaacaaat ttattctaag
    73441 ttaaaacttt tcttagaaaa atatgattta aaaggtcttt agggtaaata gaaagaatat
    73501 atttatattg aagaataaat gtaaatttgt acctaagatt acaaatatta caaaattgta
    73561 atcttaggta acagagatgt aactgattat ggaaacacta tgtgatatta tagatacaga
    73621 gagatgaaat atgtgatgaa ttatagagaa atataattta aaatgtatta atatcacacc
    73681 aaaaaggtat aatcaaaaaa tatgtaaata taaaccccaa catttagaaa aagacctcta
    73741 aggaggtttt tttcttgttt aaataactta aaatatattt ttatatcaat atatcaatta
    73801 actcttctaa aagtaagcat taccttaaat aaatcagcat ctataattat ttccatgtgt
    73861 gcattttcta attcaattat attttgagca attgataaac caagaccaga gccatctgtt
    73921 tttctagata tatcacccct tctaaatctt tctattaact cttctggctt tagatttagt
    73981 ttatcatttg aaatattttt aaacgttaat attatatttt cttcctttat aaacatatct
    74041 atatagaccc tagtgttagg catagagtat tttaatatat tgcaaattag attctcaaaa
    74101 actctccaag tttttttacc atctatcatg gtaaaaacag catattcagg tgtttctatt
    74161 ataaaatcta aactgctatt ttgaattttg tcttcaaatt ctacaatact ttgaattaaa
    74221 agttctctta tatcggtttt tgttatatta aattctacat ctccactact tagcttagat
    74281 gcttcaaata tgtcatctat taataatttt aatctttgtg attttttatc taaaatattt
    74341 atatagtcat ttatagtctc tctgtcaaag tcattatttt ttaacatatc aacatagctt
    74401 aatatagatg taagtggagt ttttaagtca tgagatacgt ttgtgataag ctctgccttc
    74461 atcctttcat tttttatatt agcatctaca gcagtttcaa gaccgcctgt tatattattt
    74521 atacttttgg ctaaagtaga tatttcatca tctcctataa cttctaattt atactttaaa
    74581 ttgccatttt ctatattttt tatatttttt gatatgttat ttatgtaatt aaacttaaca
    74641 gataaaaagt tgtatatata aaaatgaaaa actgtgttta caagtgtaaa taaaattact
    74701 atagctattg cctcagcata atatatatac ataaagaata tcaaaacaag atattggata
    74761 atagcttgta caactataga tattaaaaat actatagcta attttttatt tatagttttt
    74821 ttattataca tactaagtaa gtttg
//
LOCUS       DAFAZV010000019        73529 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFAZV010000019 DAFAZV010000000
VERSION     DAFAZV010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 73529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73529
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.019"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..888
                     /locus_tag="KOU88_001810"
     CDS             <1..888
                     /locus_tag="KOU88_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HBK3211702.1"
                     /translation="KREIDKLFLDEEYFQIEPQLFEEYDEFTTINNKIPEESMVKVVN
                     GKVMVLRADITTSIIKSLVPRWEDGLKLKLFYNSSIYKNKNTVGIKEIRQIGCEYLGE
                     ASVEADREVVKLALKILEKYNNNFILEVGSSKYIHGLLEELNLNKNCENQIKNLLYTK
                     NTHELKVYIEELKIKREVKELLSNILSLQGNLYNVIEKSNKFYCNNKMKQALEELKQV
                     NNLIEECNFLDKARFDLSMITMLDYYEGIMFRGYYPNSYKEILSGGRYDSLTKEYGKE
                     IPAIGFTLSVDELMKYVYK"
     gene            910..1536
                     /locus_tag="KOU88_001811"
     CDS             910..1536
                     /locus_tag="KOU88_001811"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBK3211703.1"
                     /translation="MDYLTIALAKGRIEGESFKKFKKMGLGDSIDTDTRKLIFKDEEN
                     KIIYIHVKPSDVVTYVEKGVADLGIAGKDTILENETDVYEIYDLGFGKCKFAVAGLKG
                     DSIYREDEYLKVATKYPNIAKKYFKEKGQKIEIIKLNGSVELAPIVGLSDVIVDIVET
                     GNTLKANGLEILEDICNISARIISNRASYRFKYEQIQNIIRLFEELDN"
     gene            1570..2619
                     /gene="hisC"
                     /locus_tag="KOU88_001812"
     CDS             1570..2619
                     /gene="hisC"
                     /locus_tag="KOU88_001812"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBK3211704.1"
                     /translation="MREKESIRELRGYEPNHVNCKVKLDANEGSKRLFKYLIKEISDS
                     DIDLNLYPEDSYSDLKESIIDYINISGVNKKNLLVGNGSSEIIDLIIHTFVDKDEVIL
                     SFSPSFSMYSIYSQINGSKFIGVESDENLVINIDNVIEKVKENNPKIVIVCNPNNPTG
                     TILKREEIIKLLDSTNSLVVLDEAYMDFGEESMLSDVFKYDNLIVLRTLSKAFGLAGI
                     RTGYMLSNSSLINSVEKVRPPYNLNSLSDFIATRALRNKDVVKAYIKEVKEEREVLYE
                     EMIGMGIKAYKSQANFILFYSEIENLSQKLIDRGVLIRKFGGKLENYYRVTIGDKEEN
                     SMFVGAIRDILKKEK"
     gene            2622..3200
                     /gene="hisB"
                     /locus_tag="KOU88_001813"
     CDS             2622..3200
                     /gene="hisB"
                     /locus_tag="KOU88_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HBK3211705.1"
                     /translation="MRIWKVERNTLETQILVELNIDGSGKAEIDTGIGFLDHMLTLMS
                     FHGKFDLKVICKGDTYVDDHHSVEDIGIAIGEAFKNALGDKKGIRRYSNIYIPMDESL
                     SMVAIDISNRPYLVFNAKFDTQMIGSMSTQCFKEFFRAFVNESRVTLHINLLYGENDH
                     HKIESIFKAFARALKEGSEIVSNEIASSKGVL"
     gene            3202..3807
                     /gene="hisH"
                     /locus_tag="KOU88_001814"
     CDS             3202..3807
                     /gene="hisH"
                     /locus_tag="KOU88_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBK3211706.1"
                     /translation="MNIIVDYGLGNIDSVSRGFRKAGIETKISSDIDEIKQADSLILP
                     GVGAFRDSISALDKLGLIPIIKEHVSKGKFMIGICLGMQLLYEKSYEYGEYEGLGLIK
                     GSIDKLDISLKVPHMGWNNLKFNKANDDILKYINEDDYVYFVHSYYANSSNEELIAFS
                     EYEKKIPAIVRKGNVYGIQFHPEKSGEVGLNILRAYGEMIK"
     gene            3804..4526
                     /gene="hisA"
                     /locus_tag="KOU88_001815"
     CDS             3804..4526
                     /gene="hisA"
                     /locus_tag="KOU88_001815"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBK3211707.1"
                     /translation="MIIFPAIDIKDNKCVRLTQGEFDKVNVYYDNPLEVAYKWKNEGA
                     EYIHIVDLNGARSEFGVNTKIIEDIANNIDIPIQVGGGVRDKEKVKSLINAGVTRVIL
                     GSIAIENLNLVEELVNEYKEKIVVSIDAKDGKVAVRGWEVVSNVDSLTLCKQLEKIGV
                     QTIVYTDISKDGMLQGPNFDIYERIAKETSLNVIASGGVTSIEDVKRLKAMNLYGAII
                     GKALYDKKIDFKEAQQLCLLGE"
     gene            4508..5266
                     /gene="hisF"
                     /locus_tag="KOU88_001816"
     CDS             4508..5266
                     /gene="hisF"
                     /locus_tag="KOU88_001816"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBK3211708.1"
                     /translation="MLTRRIIPCLDVRNGRVVKGKKFKDIVDVDSPEVLGKFYSDCGA
                     DELVFYDITASNEERKTSLEFVTKVAENINIPFCVGGGVNKLEDFTDILRKGADKVSI
                     NSSAVKNPELIREASLKFGAQCVVLSIDAKKNEEGSWSVYVKGGREKTNLDAIEWAVK
                     GVELGAGEIVVNSMDEDGMKNGYDIELLSKITSLVNVPVIASGGAGKKEDFYEAVNKS
                     NVDGILAASVFHFGEIKINDLKKYLKDMGVEVRL"
     gene            5294..5962
                     /locus_tag="KOU88_001817"
     CDS             5294..5962
                     /locus_tag="KOU88_001817"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBK3211709.1"
                     /translation="MDNKCNNVYSDEVEKFIRSIKFDDKGLVPVVVQEVVSKDVLMLA
                     YMNKDAIKKTLKDKVACYFSRSRQELWVKGETSGNTQKVVKMSYDCDVDTILLFVEQT
                     GVACHTGNYSCFYRDLFDDSSKMELEVQTNILKELYDLINERKNNPVEGSYTNYLFEK
                     GIDKILKKVGEESSEVIIASKNTDKSELIYEISDLVYHTLVLMIEKGVEIDEIKKELL
                     KRRK"
     gene            6764..8092
                     /locus_tag="KOU88_001818"
     CDS             6764..8092
                     /locus_tag="KOU88_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK3211710.1"
                     /translation="MGSNELKKTLGVSAALSTVVGSVIGAGVFFKPQAVYTLTGGAPG
                     LGILAWLIAGIITITAGLTAAEVSVAIPKTGGMMVYIKEIYGEKLGFLTGWMQIVLFY
                     PGMMAALGVIFGEQASALIGSPSLLLPIAIGIIVIVAGLNMLGSKTGGVIQTVSTICK
                     LIPLILIMVVGFIKGGGNNPILTPMVGEGLSLGSVLGQVLIAILFAFDGWMNVGTLAG
                     EMKNPGKDLPKAIIGGLSVVMAVYFIINLAYLWVLPANELANYASPASAVAEVIFGSM
                     GGKIISVGILISVFGALNGFLLTGSRVAYTLATDKTLPKYGIFSKLNSAQVPANAIAL
                     VSVIASIYALSGQFNLLTDLAVFATWIFYVLTFIGVMKLRKTHPNIPREYKVPLYPIV
                     PIIAIASGIFVVVNQLCFAGMKTTMISIGGLVITAIGLPVYAYMTRGVKR"
     gene            8845..9678
                     /locus_tag="KOU88_001819"
     CDS             8845..9678
                     /locus_tag="KOU88_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBK3211711.1"
                     /translation="MRNKKKKINRKKLYLLLSAIVVCLAFIVVGVRVSSLNMKENEIS
                     RNAKLSSSTITDIVSNTSIEVSKGPSKSSGKIAYITIDDGPSKFTDEMIKTLNKYNVK
                     ATFFMIDGNMKEYPQQVKNIIKNGNTAGFHSVSHDIHKLYVTSTSAKEEFDTNDQTFY
                     KITGKHSKVIRIPYGSKPYTPQASYQALVDAGYKIWDWDLDTEDWRSNSSQIVQNVKN
                     HIKNRKGEDKDQLVVLMHEKKQSAEALDSVLKFLSDEGYEFAPVDQNQIPKNYWLRNL
                     E"
     gene            9771..10703
                     /locus_tag="KOU88_001820"
     CDS             9771..10703
                     /locus_tag="KOU88_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK3211712.1"
                     /translation="MVGILSLMMVGCNKSLAKVNDVEITKEQYKKTKAVLSATNNYIN
                     GQSLDELEKTLDKKGRNKLENVIISFMVDNELLYQEAKDKGLTPSKSEVDSKYQELED
                     KMNLNTSYKEKMDKAGVDKDYLKQEISRDLAIDKNKKAFEDRINISDNDMEAYYTSHK
                     KDFNVEEVSASQILISTLDKNKKEVSKDKKEALKKKADNILTKIKNGESFESLAKKYS
                     DDKATGKNGGQLGYFTKDDKNAEFTKEVFKLKKNEVSNVFETSYGYHIVKVTDKRERQ
                     KSFNECQSLIRESILNEKYIEHIKKLNEDAKIDR"
     gene            10755..11237
                     /locus_tag="KOU88_001821"
     CDS             10755..11237
                     /locus_tag="KOU88_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3211713.1"
                     /translation="MFKSLKRTKVEKYIIDNKDSFYRIAYSYTKNEEDALDVVQESMY
                     KALYSVENIKEVNYIKTWFYKILVRTSIDFIRKNRKYNNMTDIDLIDETGEYDKYTDL
                     DLRRALEELPIEYKSIIILRFFEDLKIEEVAIILDENVNTVKTRLYTALKKLKLKIEE
                     "
     gene            11249..12118
                     /locus_tag="KOU88_001822"
     CDS             11249..12118
                     /locus_tag="KOU88_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBK3211714.1"
                     /translation="MTSKERLNKLKDEYHKIPIPKKLDTIINHEKIENIYREKNKKVN
                     RLRFKVAIAFACIFTVLVNISPVFADNFSKIPVIRAIVEVITIKNYSLKSENYEAEID
                     IPKIRGLKDKNLEQRLNSSFMEDGKRLYHQFQERMEKIQSSKNKGYKSLSLSYSVKNN
                     SKKFLSIEMTKNEIEASSYVSKVHYTIDKKRQIVLTLPMLFKDDKYIKVISDNIKEQM
                     REQMKKDSTKSYFIDQKKDLPVEDFKTINKYQDFYFNKNEDLVICFDEYEVAPGYMGA
                     VEFVIPYKVIKDL"
     gene            12161..12916
                     /locus_tag="KOU88_001823"
     CDS             12161..12916
                     /locus_tag="KOU88_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBK3211715.1"
                     /translation="MTTYKKLKKSIFKIAIFSICLLVSLVDTNPIFAGSSFNETSNSD
                     TIKVLNAKSINFKQDNYEVNVSIPKIKGLKDKTLENKLNNELLQDGKKIYSEFQNKMK
                     KEDNKGHRYLNVIHNVKNNSKDFLSIEMTKEEIEASSSITKKHYTVNKNRGILLNLPI
                     FFKDSRYIRAISDNIKEQMRNQIKKDDTKSYFIDQDKDSPVKDFESINKYQDFYFNKN
                     GNLVISFDEYEVAPGYMGAVEFVIPNKVIKRLR"
     gene            12958..13779
                     /locus_tag="KOU88_001824"
     CDS             12958..13779
                     /locus_tag="KOU88_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase accessory factor"
                     /protein_id="HBK3211716.1"
                     /translation="MNIYEQAIRLIENNEDFAFATITSHSGSTPRETGAMMIVKNDST
                     IFGSVGGGSVEAECIKHAINVIKNRESMLYKFTLNKSDVAKLGMICGGTGEIQIDFID
                     SKLKSNIEKFNKRLKENTSKAYIFGAGHISRDVAVILSLLEFRTVVIDDREEFANHER
                     FPESEVVVLDSFENIPDFPTDENSYIIILTRGHLYDSSALEWALKREAGYIGMIGSRT
                     KIGLTYEKLMKKGFKKEELSKVHAPIGIKLNAQTPAEIAVCIAAELINCRANKEK"
     gene            13784..14545
                     /locus_tag="KOU88_001825"
     CDS             13784..14545
                     /locus_tag="KOU88_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBK3211717.1"
                     /translation="MNTGSKDIDTLKVNFRGIEIKAVLVYKNRKNISIKINPFGKITV
                     MSPPKISKKIIKDIIIEKGDWILKKSEKCKGREEVYKQRMFITGEKFLYLGEEYHLVI
                     KELLRDSVKKSNCRITINEYQIFVQTNDTSTDFIKKSLKSWYKMESERIVLERIDFLK
                     LNCEIMKQLVPASVKVKEQNKRWGSCTAQKNIYINSKISMARLDVIDYVIIHEFSHLV
                     HMNHSKKFYDLVKSIMPDYKDKENWLKINGYKIII"
     misc_binding    14706..14963
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15076..15315
                     /locus_tag="KOU88_001826"
     CDS             15076..15315
                     /locus_tag="KOU88_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBK3211718.1"
                     /translation="MENTVYAKLNQGIDSFLRVAMTLRRREVDIQSISMTVDNMNNSG
                     IKLIVNEEKTSLDSVLNHMKKLHDIREITVERMRH"
     gene            15619..16614
                     /gene="ilvC"
                     /locus_tag="KOU88_001827"
     CDS             15619..16614
                     /gene="ilvC"
                     /locus_tag="KOU88_001827"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBK3211719.1"
                     /translation="MKMARMYYEKDVDLEVLKNKKVAVLGYGSQGHAHAQNLRDNGVH
                     VMIGLYDGSKSAQKAKEDGFEVKSVAEATKESDLTMMLMPDEKQKKVYEESVKDNLKE
                     GQTLAFAHGFNIHYNQVQPPEFVDVVMVAPKGPGHLVRNVFTKGSGVPALFAVYQDHT
                     KKATETVLAYAKGIGATRAGVLETTFKEETETDLFGEQSVLCGGISELIKLGYKTLVD
                     AGYQKEVAYFECLHEMKLIVDLIYEGGFERMRYSISDTAEYGDYVSGKRVITDAAKQG
                     MQNVLEDIQNGKFAKAWIKENEEGRENFLKTREEEYNTEIAEVGRNLRSMMSFLK"
     gene            16667..18355
                     /gene="ilvB"
                     /locus_tag="KOU88_001828"
     CDS             16667..18355
                     /gene="ilvB"
                     /locus_tag="KOU88_001828"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HBK3211720.1"
                     /translation="MNGAKVILECLKKEGIDTIFGYPGGAVIPLYDALYDYSDDFKHI
                     RTSHEQGLVHAADGYARSTNTVGVCFTTSGPGATNAITGIATAFMDSSPMVVISGQVP
                     TSLLGKDSFQEIDITGATLSMTKHNYLVRNTKELVPTIKEAFRVANSGRKGPVLVDVP
                     KDLFLAEMDFSGEDYDLCQIDDYMDYKSDFDLDDETNIKLLNEAIDIIKESKKPVIYA
                     GGGVKSSDSEEILEKFATKIDTPVLNTLMGLGNIDRKNELSLGMVGMHGSRESNLALS
                     NSDLVIAIGARFSDRVISKSSEFAKNAKIIHIDIDPSEISKNIESNVSLVGDVKLVLS
                     LLIERVESKNNSNWKEEIKRFRKSEGVQTYEFHPQNILKKINEKYETLKKPTVVVTDV
                     GQHQMWAAKYWNFKGNKSFITSAGLGTMGFGLGAAIGTKVGNVDKNVVLVTGDGSFRM
                     NCNELATVANYNVPMLILLLNNRTLGMVRQWQKLFSNQRYSQTDINENVDYVKLVNAY
                     NIDGYKVSSMEELGKALDMIDFNKPVFLQCDIDKDYDVYPIVAPNDALENLICN"
     gene            18566..19243
                     /locus_tag="KOU88_001829"
     CDS             18566..19243
                     /locus_tag="KOU88_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBK3211721.1"
                     /translation="MFKHDKALLKEVKVERPNPQYAVLMQEQLGGANGELKAAMQYLS
                     QSFRIKDPQIKDLFLDIAAEELSHMEMVAQTINLLNGHDVDYNAVNTGEIETHVLTGL
                     SPVLINSSGAPWTANYVTVTGDLVADLLSNIASEQRAKVVYEYLYRQIDDKYVKETID
                     FLLNREEAHNALFRDALNKVKDTGSNRDFGVTEDSKLYFDLSTPGPNHDTKIDINPPS
                     FEKPLKK"
     gene            19412..21448
                     /locus_tag="KOU88_001830"
     CDS             19412..21448
                     /locus_tag="KOU88_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin domain-containing protein"
                     /protein_id="HBK3211722.1"
                     /translation="MDSNRKPNNLINEKSPYLLQHAYNPINWYSWNDEAFKKAKEEDK
                     PIFLSVGYSTCHWCHVMEKESFEDEEVAEIMNRNFVAIKVDKEERPDVDSVYMTVCQA
                     MTGSGGWPMTIIMTPDKKPFFAGTYFPKYSRYNRPGVIDLLENVSEKWNTSRDILIKS
                     GDEIIEALKDDFGVKNTEGDLSKEMLSSSVRVFKAIYDEKYGGFGNAPKFPSPQNLMF
                     LMKYYSIEKDKDVLKMVEKTLDGMYRGGLFDHIGFGFSRYSTDKKWLAPHFEKMLYDN
                     AMLTIAFLDAYKITKKELYKEIAIKTIDYVVREMKDKEGGFYSAQDADSEGEEGKFYT
                     FNPLEIIEVLGEEDGTFFNNYFDITSSGNFEGKSIPNLIKNKEYERHNEKIADLSKKV
                     FEYRKERTSLHKDDKILTSWNALMIVALTKAYSTLKNDIYLEYSNKCLNFINNNLVNE
                     SGRLLARYRDGSSDYLAYLDDYAFLIWAYIELYESTFNMKYLEKALNLNESCINLFWD
                     YEKSGFYIYGKDSENLIARPKDLYDGAIPSGNSVQLYNLIRLAKITGDNRLEEMSYKQ
                     LKLYVDNVKSSPTGYSFYMLSLMFELYSTKEIICIFKEDSDLIAFKELISENFIPNAT
                     FLAKKYNEENTIIGFLNNYILKDDKTSYYVCQSNSCSQPINDLQKLKDMILGVE"
     gene            complement(21639..22205)
                     /locus_tag="KOU88_001831"
     CDS             complement(21639..22205)
                     /locus_tag="KOU88_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3211723.1"
                     /translation="MDYSNELKELFLMNQTYATLFTLTNKIQIEGDKYFGILTSRQYM
                     TILSILHLPEEETTLNNIARKMGTSKQNINRLVANLEKNGYVDVIPSPHDKRAINVKV
                     TDLGKKVMVTCSRTGINFMADVFHEFTKDELETLWSLLKKMYRFNGEEQDGFEEDANF
                     MEYEEIDKIKSEALEEFAKRRNRVNKKD"
     gene            22493..23428
                     /locus_tag="KOU88_001832"
     CDS             22493..23428
                     /locus_tag="KOU88_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3211724.1"
                     /translation="MKCTNFTFKGEEGLDIYTYKWEDENIKKPKAVIQIAHGMAETAQ
                     RYETFAKVLTKNGYIVYINDHRGHGKTAKIIENVGHLAEKEGFRCLVEDMYTLTNIIK
                     KENEDLPIYLFGHSMGSFASQRYIMDYSNNLSGLILCGSNGKQGIILNLAHLIINREI
                     KKYGRRSKSNKINNLIFGGEIIRRNEKTKFDWLSRDKEQVEKYINDPFCGVVCSCGFF
                     YDLVQGLKEIEDKENLKKVPLDIPIYIISGDKDPIGKNGKGVLRLRDRYIKLGVKDVT
                     CKLYKDGRHELLNEINREEVFEDIICWLNNKIEIL"
     gene            23893..25107
                     /locus_tag="KOU88_001833"
     CDS             23893..25107
                     /locus_tag="KOU88_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211725.1"
                     /translation="MQIKIGKVIQCLRKERNLTQEQLAKFIGVSTPAVSKWESGNSYP
                     DIELLPLLADFFNVSIDKLLNYKIDLSEEEVMKIYKELESGFARIEIDLSTEEPKEEF
                     RQDLESVKKLSNMYIEKYPKSYLLKLRICSLYQMYSYKFGKSELNDRVKETTNILEDI
                     VRNTDDIQIKETALIILSNAYCMLEDYEKAELYLNMIHKSIGDTSVNLAMIYLNQNRL
                     EEAEILLQNKLFSNVFNISMDCKGIINVYKNQYKELKKKLENRNFNKNAIEREMEYIK
                     NKLLGYANLSLEIKKMLSEDKGAFFSMYMDYMELSLIFLFFNMKEEAKKALYSLKEIL
                     EKYPIHENLDVSQMRFFDKVESKNLYTFNIYTNLLIVLNDDSYNELREEPIFKDVIEK
                     ILDMEKMLKNKE"
     gene            complement(25527..26048)
                     /locus_tag="KOU88_001834"
     CDS             complement(25527..26048)
                     /locus_tag="KOU88_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3211726.1"
                     /translation="MKFERLRTSENKLYYKAMELYKISFPFHEQRKSSLQAEILKNKE
                     YQFNLIYDKNQFVGIILCWETDDFIYVEHFCIFPEMRNNRYGQRALELLNKKGKTIIL
                     EIDLPIDEISIYRKAFYERVKYKTNNYEHIHPPYHEKFNGHNLIVMSYPEKLSKMEYD
                     KFNHYLRNNVMSF"
     gene            26404..27201
                     /locus_tag="KOU88_001835"
     CDS             26404..27201
                     /locus_tag="KOU88_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBK3211727.1"
                     /translation="MEKREKRIIISSLLSVSILMGLASIYSILNKEDISLTVKGQEQK
                     VSSFKKTVEELLDEQGVKYNSEDKINPSLDTELKDDMKIKVVKVTKSKKEEIEKIPFD
                     TKHVNDSNLLKGKSKVYQEGQEGEKKLVYNLTYHDGKLVKKVLSKEVISKEPTTKIIK
                     YGTKEKVLIASRGANIRGGKHMKVVATAYAGDTITSTGTTPRWGVIAVDPRVIPYGTK
                     VYIPKLGMTFVAEDCGGAIKGNRIDIFMNSEGKASNWGRKSIDIYLH"
     gene            27311..27901
                     /locus_tag="KOU88_001836"
     CDS             27311..27901
                     /locus_tag="KOU88_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBK3211728.1"
                     /translation="MKIVCLGDSLTYGFGVSRSNSWTNIVNKETRLEILNKGINGDTT
                     SGMLARFNEDVVKNSPDIVFIMGGTNDFIAGAGNEIINSNIMAMVHQSYSKNIIPIIG
                     IPLKPDIPNVREDWSCFTDFNIVSQNLESYSYWIKKFCMTFNTNFVDFYSEYNKNMEL
                     EGYKKLYFDGLHPTKEGHRIMADIFINSINKYIEEL"
     gene            27967..29664
                     /locus_tag="KOU88_001837"
     CDS             27967..29664
                     /locus_tag="KOU88_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBK3211729.1"
                     /translation="MDYTKTYEEWIKGSYFDEDTKLELENIKNNEKEIEDRFYKDLEF
                     GTAGLRGIIEAGTNRINKYTVRRATFGLANYILENTTKEETSRGVVIAHDNRHKSRQF
                     CIESANTLAACGIKAYIFDSLRTTPELSFAVRSLNAIAGIVITASHNPPEYNGYKVYW
                     EDGAQVMPEIANAITEKVNSIHDYSTIPTLTEANKNLVVLLDESQDTKFIEAVKSQII
                     RKDLVKNVGKSFKIVYTPLCGTGNVPIRRALKEVGFENIIVVPEEENPDPNFAGLDYP
                     NPEEKKALNRGILLAKEKGADLVIATDPDCDRVGVAVKTTTGEYALLTGNQIGGMLTH
                     YIIEGLKENNKLKENPTIIKTIVTSEFGADIAKANNVDVLNVLTGFKFIGEKIKLFEQ
                     NKNRSYVFGYEESYGYLVGTHARDKDGVVSSLLISEMAAFYYSKGMSLYDGLIELYKK
                     YGFFKEQTISLTLKGIEGVEKIKEIISYFRENQIDYINSIKVVDKKDYKNGIDNLPKS
                     DVLKYFLEDESWVAIRPSGTEPKLKFYIAVKGASDIEADKKIQGLKKYIDDMVEKLK"
     gene            29878..30717
                     /locus_tag="KOU88_001838"
     CDS             29878..30717
                     /locus_tag="KOU88_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBK3211730.1"
                     /translation="MFGIDKKLIEYIIAKSNYSELSSKSAEVSFFLMLSIFPFLIFTI
                     SSIAYIPILHLNKYIALFRNMMPEGAFAVLSSIIVSAIDNRNLKFLAVSFVLTMWTFS
                     RAVKALIKGMNRAYKVKETRSFFKILSISFLFTIMLLVLIFLSMIFLVYGEKIGYFIF
                     NLVGLDEIFIKIWDILRYTVGIITIIVIFTLLYKYTPNKKLTIKESAPGAIFATFAWF
                     LVSFLYSYYTNYYANYEVIYGSIAEIIVLMTWMYFSSWSIVIGYEVNSRLYFRKIRHE
                     MLK"
     gene            31234..33090
                     /locus_tag="KOU88_001839"
     CDS             31234..33090
                     /locus_tag="KOU88_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBK3211731.1"
                     /translation="MDTHNKYVNFIKNIPVPFLYCRIVKRQEDIEYRVEYISKGMGKV
                     LQLEEGICDKNILDVLPVFKSKKYFKELFSNEVDCIKRYIPTLKNWINIKKQIIGDSY
                     IILYFGKIVFDYRQIIDSFDKKEKVAYIKDEEGIYIDCSENLIPILNNNIKTTKDIFG
                     KNDIEVWGENTGKLFRDDYREGVSSKKRFLQNLFEYEETFFMVEKYFLYDEDELLGTI
                     GIVDNIIYSGYSNRNYNSKDLMKMIEHSIPENMFYKDVYGNYIGFNSGFLNLACMNKE
                     ELLGKNSYKISEEEALIDKIFESDKGVVENKKVVTFELNISMNDENKCIEITKRPFFD
                     SYGSVIGIIGTARDISRRKRLEEEMDKTRMEFFANLSHELRTPINLISSSLQVIEKKE
                     ADLIESNDTLKRNLGIIKQNGNRILRLVNNVIDFTKMQSGYLDFKPEESDIIAFIEEI
                     CMSVADFASQNNIQLTFDTEIEEFSMLFDSEKLERIILNLLSNGIKYNKKDGKINIFL
                     YVKDNVFNMKISDSGIGIPKEKIDKIFNRFEQIDNELSYRVKGSGIGLSLVKSLVELH
                     EGSISLKSQLGIGSEFIVSLPVRSKNNIEKYNHKREISNELSKKLEIEFSDL"
     misc_binding    33173..33413
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    33479..33714
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            33799..35016
                     /locus_tag="KOU88_001840"
     CDS             33799..35016
                     /locus_tag="KOU88_001840"
                     /EC_number="1.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HBK3211732.1"
                     /translation="MENKVKIGVLGYGVVGSGLIDIIDNNKEKRNIEIVGILVNNLEK
                     HKDKKYSNIITNNIDDIFNKDIDILVEVMGGLEPSLSYIKKALNNKIHVVTANKDLLA
                     ECGDELAKLASENKVSIKFEASVAGGIPVLKPIIESLEGNNIDSINAILNGTTNFILS
                     KMYDENLSYDMALRQAQELGFAEANPESDVLGYDAARKLSILSTLAYDNRVYWKDVYL
                     EGITDIDEKDIEYAKKLNCKIKLIGQSKYENDKVSAFVRPVLVEKDNILARIDNEFNA
                     VIVNGDSVGEVSFVGKGAGSLATGSAVYSDVIDIIDNRVSSIDSFTKDKIQVNKIVRE
                     KCGALLRFKKCNKDEILNIVENCLVKFDILNDDDELAIMVYADSEYEINNSLCLIKDK
                     GYCEKMNKMLKIS"
     gene            35133..35615
                     /gene="cdeM"
                     /locus_tag="KOU88_001841"
     CDS             35133..35615
                     /gene="cdeM"
                     /locus_tag="KOU88_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeM"
                     /protein_id="HBK3211733.1"
                     /translation="MENKKCYSEDWYERGESTAKWFQNDREEYEREAYDEDRERRGSN
                     CGCSDSGENRPRNCERFRREAEIREREAREAFCESSEKKKEALAYECEARKLWEEAEK
                     YWDEYSKYNYKGIEYLAEAARLFDEGMECEARRNGNNGGNNNNCCHKCHKCNCNCCRK
                     "
     gene            35880..37145
                     /gene="hisD"
                     /locus_tag="KOU88_001842"
     CDS             35880..37145
                     /gene="hisD"
                     /locus_tag="KOU88_001842"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBK3211734.1"
                     /translation="MKSIKTSSMKEKVDEKILREQVSSIIEDIRNNKDVALKKYNEKF
                     DRNTRDEFRITKEEIKEAYKHVDDEFINNLKIAAKNIREFAKAQKLSFENPFEKEIYP
                     GVILGQTNIPIESCLAYVPGGQYPLFSTALMLIIPAKVAGVKRIVACSPTMKNTEKIN
                     PKTLVAMDIAGADEIYATGGVQAIAAFTYGTEKINPVDIIVGPGNKFVTEAKRQCYGQ
                     VGIDFVAGPSEVLIIADETSNPVYIAADLLAQCEHDLNARGILLTNSLEVAQKVEKNI
                     ESMLKDLPTKDIAYSSWENNGEIILVDDMEEAIKISNFYAPEHLEVAVNEYNDICDRL
                     TNYGSLFIGNLSAEVFGDYVSGTNHTLPTLKASRYTGGVWVGTFIKTCTKQIFNEKAI
                     QSLAPVAEKLAKEEGLYAHAKAAEVRFKK"
     gene            complement(37348..38100)
                     /locus_tag="KOU88_001843"
     CDS             complement(37348..38100)
                     /locus_tag="KOU88_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3211735.1"
                     /translation="MSYFQYQGNSCFYKEYGQGKPIIFLHGNTGSSNMFKALVPLYAE
                     NFRCILIDFLGNGQSDRVSQFSPDIWHDEALQTIALIEHLNCGKVGLIGTSGGAWAAV
                     NTGLERPDLVEAIIADSFDGRTLNDNFIDNLITGREKSKQDIQARKFYEWCHGKDWEN
                     VVNLDTKALLQCANEKRPLFHKELCKLEMPILFTGSKEDEMCRHNLEEEYKQMATFIS
                     KASIYIFSQGGHPAILTNADEFAQLAKVFFKY"
     gene            complement(38218..38487)
                     /locus_tag="KOU88_001844"
     CDS             complement(38218..38487)
                     /locus_tag="KOU88_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211736.1"
                     /translation="MSYQNSIDLLPKELIEQVQEYIDGKVIYIPKKQEHKKHWGENTN
                     TKQVLASRNSQICINFQNGMSIKQLSEKYFLTEKSIQRILKQQNL"
     gene            38962..40056
                     /locus_tag="KOU88_001845"
     CDS             38962..40056
                     /locus_tag="KOU88_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK3211737.1"
                     /translation="MKNIVGKPQTIKKVNEDLIKNIIKNEGPITKPEISSITELSLAT
                     VNKIVEQLALKNEVKVSGLSESTGGRRAQLFEINANLEHIIALYYYRNCCIGVVANLL
                     GEIIYQEEFNIRMDTYENVNQDTFFVIDTLIKKEKGNNIRAIGIGVPGVVKKGVVKNI
                     PTIKSWEGINLENLIKSKYNTKVFIENDTNITTIGIYQKQYKDKYKNMALMYLEDGIG
                     SGIVINGELYLGSTNFAGELSYLNIEFGKYNSNNLNLEDYIMSLRKRYLESKDNKFKK
                     EILSIISNFIRTLVCVLNPQAMIIQCSILTKSDMEFIEKDVSNNVGEENFPKLIKVDS
                     LREGSINGVISMCLKETDYQYSLSNKKGGY"
     gene            40058..41008
                     /locus_tag="KOU88_001846"
     CDS             40058..41008
                     /locus_tag="KOU88_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBK3211738.1"
                     /translation="MKYLVSIDGGGTKTKFCVSDLDGNILKEHTTGSTNYKSVGIKKT
                     YENINNGFKKILKDLYIDYDDIEYTVFGISGCDSPNDYKIIMDEILKIGINKEKIYLA
                     NDAVLAFYAQADSPGLVIVAGTGSIILGIKEDGEIYRVGGWGYNFSDLGSGYDIGRKL
                     LKKVLLYCDECHEYSDLFSCVLDFFGANSFEQLAYMITDINDNVEIANLASLVIDCAE
                     RGDKLAIEILRESSTELSKLAQVILRKISNPMKMDKSEINIVLSGGTLNKTVYAQMLM
                     NNLKTENTDKNLKFISQENQPVYGGIRLAMALANRRVNHG"
     gene            41001..42185
                     /locus_tag="KOU88_001847"
     CDS             41001..42185
                     /locus_tag="KOU88_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211739.1"
                     /translation="MDRKKVIVQIFTGGFKAKEIKFNDIKCKLLELLDCIDIEKVIMG
                     WSVDEELYVETKKLLNKYNVELYLWLPCFSEIGLLEKSNLLIDYMGKEVKGYALQEDE
                     NFEFYCPNNKENIKNIKKIYSTYFSDIKFDGIFLDKIRYGSFSNKLNGVFNCFCKDCL
                     NIYEKNNIDKESLMREMNNVSKGVIDNEDTPFGITEYINGKYKFKNKIWEDFFETKNQ
                     NIYKALLEISSYFKSKGLKIGIDTFSPFISYFTGQDLEKLQEVADFIKPMMYRTTKAP
                     AGLPFEFERFIDESIHKNKEIGKRNFLDILGIKEYEGDVYPIEFVLEEIDFMTRNLNK
                     DVYVGVEINKKEIISPVTPKYISENISNINKTTVKGYVLSWDLLSAPKENIDEIIKWF
                     RN"
     gene            42198..43694
                     /locus_tag="KOU88_001848"
     CDS             42198..43694
                     /locus_tag="KOU88_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBK3211740.1"
                     /translation="MSKILEMQQIYKSFGKVDVLKGINFELEKGEVRALLGANGAGKS
                     TLIKILGGVHSQTKGKVILTGNEIMFKNPHHSKENGISIIYQELSLIPTLTVLENIFL
                     GREILKGSVFLNKKDMLEEYMKICEDFDFNIDPHIVVSNLSVANQQMVEIMKAVSCNS
                     EIIIMDEPTTSLTNNEKDGLFKIISRLKSKGKTIVYISHILEEVFKVCDSASIMKNGI
                     MIGTYDVEDLTKLKITQLMTGNDNHKLIEKKDYTFAKYEEPPVLEVKNISWSNKIKNV
                     SFKVYRGEVVGLAGLVGSRRTEIINLIFGIDNKDSGDIFINGKKVDITSPKVAIKNKI
                     GLIPEDRKNLGLILEQAIYTNSSSVQIDKFKKFLFIDRNKEIEFSKKGVKELGIKVSD
                     VKQEVKELSGGNQQKVVVSKWLEKDLDLIIYDEPTKGIDIAAKEDIFNTIKEFSSKGI
                     GVIFISSDLEEVIRVSDRILVTREGSIVDDLKNENIQVQDIMNSIFNV"
     gene            43717..44667
                     /locus_tag="KOU88_001849"
     CDS             43717..44667
                     /locus_tag="KOU88_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211741.1"
                     /translation="MKKAFEKLNLRDYGVLLGFLALCIAISIATPSFLGKQNILNLLR
                     QSSIIGIISAGMTFVIISGNFDISVGAVAALAGAITMKFATGGTNLFASMLLGVAICA
                     VIGLINGIVVAKINVPSLIATMAMVTIVRGLLLMLTGGYPITENIPILDYIGNGYLFS
                     IPIPVVIFFIVVLASFIVLNKTKFGRYVYSVGGNQEASKLNGINVDSHKVKVFIINAV
                     LAGIAGIVLTGRLGTATAIAGEGYDMDAIASVVIGGTSVAGGSGSVLKTVIGVLLMSV
                     INNSFNLLGIDVYFQYIFKGLIILAAVGFDSYSKKKLASR"
     gene            44688..45650
                     /locus_tag="KOU88_001850"
     CDS             44688..45650
                     /locus_tag="KOU88_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBK3211742.1"
                     /translation="MKKLMKHLALLLSLVMIFGLVGCSNGGDKEKNGEKKIAVLLPGS
                     TGYFVATKQGIDAKSKELGVSVEYADAQWDASKQLSQAEDFMAKGVDMIALCGVDSAV
                     SERIVKAANDSDVPIVAFTNSIGSNPTGEFKGLVTYIGQNEEETGALTGKIAKNLLGE
                     TGGKAVLIEGVPGTTPQVLRKKGLEKELKDSNIEIVYNQTSNWEKEQALKVTEDLIQK
                     KTDFNVIICQDDNSATGAGQALKDAGLKDKVKVIGLGGSKDGLKAITDGLIDGTTYMS
                     AVEEGGLVIEKASKFLKGEKIEPVTQIKQVEVNKDNISEFKGEW"
     gene            46022..46654
                     /locus_tag="KOU88_001851"
     CDS             46022..46654
                     /locus_tag="KOU88_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK3211743.1"
                     /translation="MARRLFLERIGLIFLGSAILAFGVYNFYYLNNITEGGVLGILLL
                     LKNLFNIQPAIANVVIDGLLLLVGYKFFGKKFLIYSIVASITFSVLYDLFEAIGPLVP
                     QSQNMLLSTILAGVTVGTGVGIVVKAGCASGGDDALALVISKTTSLNIGQVYLATDVI
                     VLLLSLFYLSAFDIFYSLIAVTISGKVIDFIYYHGKSLDMDISNDIVPEC"
     gene            47065..47157
                     /gene="kdpF"
                     /locus_tag="KOU88_001852"
     CDS             47065..47157
                     /gene="kdpF"
                     /locus_tag="KOU88_001852"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: protein motif:HMM:TIGR02115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBK3211744.1"
                     /translation="MEGLPMWFLAVVIIMLIIYLVYALINPEKF"
     gene            47198..48880
                     /gene="kdpA"
                     /locus_tag="KOU88_001853"
     CDS             47198..48880
                     /gene="kdpA"
                     /locus_tag="KOU88_001853"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015391009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBK3211745.1"
                     /translation="MFMVQIVIVLAIFMILVIPMGKYLYHIATNQKTFGDRLFDKVDN
                     FIYKVCSIDKKKEMNWKQYALALLFTNAVMVFIGYIILRTQSMHIFNPSGIKSMEQGL
                     SFNTIISFMTNTNLQHYSGESGLSYFSQMTVIIYMMFTSAATGYAAAMAFVRGLVGKK
                     KTLGNFYVDLIRITTRVLLPGALIIGLILVTQGVPQTFAGTETVTTIEGKLQDIARGP
                     VAALESIKHLGTNGGGFFGSNSSHPFENPTIISNIVEILSMMILPGACVVAFGHMIKN
                     KKQGWVVFGAMSIIFLIGLVVCFKAESAGNPILSQLGLNQSMGSMEGKEVRFGIAQSS
                     LFTTVTTSFTTGTVNNMHDTLTPLGGLVPLLNMMLNVVFGGKGVGLMNMLMYAIIAVF
                     LCGLMVGRTPEFLTKKIEGKEMKLIALLIILHPLLILMFSGLSVAIPAGLEGISNPGF
                     HGLSQVLYEFASSAANNGSGFEGLGDNTMFWNITTGIVMFFGRYVSIIVLLAISSLLA
                     SKKAVNESIGTLRTDNFTFTIVLVLVVLIVGALTFFPALALGPISEHLVLWH"
     gene            48905..50962
                     /gene="kdpB"
                     /locus_tag="KOU88_001854"
     CDS             48905..50962
                     /gene="kdpB"
                     /locus_tag="KOU88_001854"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010966942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBK3211746.1"
                     /translation="METKKTKFITKDIFKTSIIEAFKKLNPKYMMKNPVMFVVEIGFI
                     VTLILTIVPSLFGDEGNNLRAYNGIVTIILFITVLFANFAEAVAEGRGKAQADTLKKT
                     RKDTVARVIDTLGNEKMISASELKLGDIVLVNAGEVIPNDGEVIEGIASVDESAITGE
                     SAPVMRESGGDFASVTGGTTVVSDWLKIRITTKPGESFLDKMIALVEGASRQKTPNEI
                     ALNTLLVGLTLIFMVVLISLYPMANYAGVKIPISTMIALLVCLIPTTIGGLLSAIGIA
                     GMDRVTRFNVIAMSGKAVEACGDVDTMILDKTGTITYGNRLASEFIAVGNADSKDLIN
                     YSVMCSLKDDTPEGKSIVDLGMKLGSTGKTKEAEEAEFVEFSAQTRMSGINLADGRAI
                     RKGAYDSIIKRVKESGGTVPEDLEENVNRVAKLGGTPLVVCVDNEIYGIIYLKDTVKS
                     GLVERFARLREIGIKTIMCTGDNPLTAATIAREAGVDGFIAECKPEDKIDAIKKEQLE
                     GKIVAMTGDGTNDAPALAQADVGLAMNSGTTSAKEAANMVDLDSDPTKILEVVEIGKQ
                     LLITRGALTTFSIANDVAKYFAIIPAIFTLAIPQMEILNVMKLSTSFSAILSALIFNA
                     IIIPCLIPLAMKGVKYRPMKSQAMLMRNMLIFGLGGVIVPFLGIKLIDLLITPLVMVL
                     NLG"
     gene            50981..51607
                     /locus_tag="KOU88_001855"
     CDS             50981..51607
                     /locus_tag="KOU88_001855"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBK3211747.1"
                     /translation="MKTLKPALLVSIVLLVVCGLVYPLVLTGVSQVAFKDKANGSMIE
                     VNGVKVGSELIGQSFTDARFFKGRVSSVNYNTYTKEDLVPDKDGNTSYGGVSSGSFNY
                     GATNPELHDRVQKDIEKFLKDNPTVKREDIPTDLLTASGSGLDPNISPASAKIQIPAI
                     AKASGISESKLQKIVDDNTSKKLFGVLGEDRVNVLKVNVEVAKILGLI"
     gene            51844..52752
                     /gene="cysK"
                     /locus_tag="KOU88_001856"
     CDS             51844..52752
                     /gene="cysK"
                     /locus_tag="KOU88_001856"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBK3211748.1"
                     /translation="MLYNNALELIGNTPVVRLNNLGCTNGCSNIYVKLEKVNPAGSIK
                     DRAVYEMLEGLEQRGELKKGDVLVEATSGNTGIALSMIGKLKGYEVVIVMPETMSVER
                     RDLMKAYGANLVLTDGKAGMAGSIEKANELLKENPNYKSLKQFENKDNPNAHYKTTAV
                     EIMNDVKDLDIFVCGVGTGGTLIGTARYLKEQNPNIRVIALEPKKSPAISENKTGPHK
                     IQGIGANFVPENYDSSVVDEVILVDDEDAFDTVKLLAAKEGILVGISSGANIFGAIEM
                     AKKYPDKKIVTVAPDGVDKYMSMGIF"
     gene            52779..53369
                     /gene="cysE"
                     /locus_tag="KOU88_001857"
     CDS             52779..53369
                     /gene="cysE"
                     /locus_tag="KOU88_001857"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBK3211749.1"
                     /translation="MFKKINKDIEYIMKNDPAARSKIEVFLLYPSVHAMIMHRMAHAL
                     YKKKKLFTARLISQISRFMTGIEIHPGAKMGEGILIDHGMGVVIGETAEVGNRVTIYQ
                     GATLGATGKDTGKRHPTVGDDVLIGAGTKILGPLNIGSNSKIGANSVVVKDVPNGATV
                     VGIPAKIVKIRNLEPVKKNKKEVSYEYDELDNVYYI"
     gene            53529..53717
                     /locus_tag="KOU88_001858"
     CDS             53529..53717
                     /locus_tag="KOU88_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBK3211750.1"
                     /translation="MKANVNQDTCIGCGLCPSICPEVFDMKDDGKSHVIVDEVPSDAE
                     ESAAEARESCPVDAIDVH"
     gene            complement(53771..54640)
                     /locus_tag="KOU88_001859"
     CDS             complement(53771..54640)
                     /locus_tag="KOU88_001859"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HBK3211751.1"
                     /translation="MKLNRNDSCWCGSTKKYKKCHMDMDNKIDSFAKLGHIVPTHDII
                     KNESQIEEIKKSAVINTKILDYISDKIEIGMSTEDINKLVHDFTLQNGAIPAPLDYNG
                     FPKSVCTSVNNEVCHGIPSKDIILKDGDIINVDVSTIFNGYYSDASRMFMIGNVNENA
                     KKLVQVTKECVQKGLEVAKPWGFLGDIGDAINSYAKKNGYSVVREIGGHGVGLSFHED
                     PFVSYVSKKGTEMLLVPGMIFTIEPMVNEGTHEIFVDEENNWTIYTKDGKLSAQWECM
                     VLVTETGVEILTE"
     gene            complement(54837..56081)
                     /locus_tag="KOU88_001860"
     CDS             complement(54837..56081)
                     /locus_tag="KOU88_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211752.1"
                     /translation="MENNLNTAKRNNTELLQNDSLKVNLQIGVDFTLLSKSLKAFYKK
                     EKDFYCIALAPCNVSSEKANRKISIYDMIKEINILIESITDKNELLSEELFTNNLSEF
                     YDESLDEIYIDLKQAYLYIKKNTDSLNIEDSIEYVFDVDISNDIKAKENPLINFNSLS
                     LVVWSGETKHILQQMNILDLEDIHSYSIENNTNITIYENNTLQYKFDEESENIKDSSI
                     DIIEQMLILPDDLNYDKDEVENMKNRLAKINSKYLQTLKEKDIKIKLINSNLTDEPEF
                     SDLKYQLPPCWVRSGKTWKDVPGIYRNNSIVAKIGYSNPSYANVHSSKNLELHETAHA
                     IDKNVLNKKSNSEEFMEVFAQERYKLYDPKQVAHAYISKFIEEFFAESFVHYYLDEDS
                     KNTLKENCPLTYDFLEKLELNY"
     gene            56372..56683
                     /locus_tag="KOU88_001861"
     CDS             56372..56683
                     /locus_tag="KOU88_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBK3211753.1"
                     /translation="MYFTYIIRCKDDSLYTGYTSNIVRRMNEHKLGINSKYTRAKGFE
                     KLEVYFVTNTKSNAMKLEYYIKKLTRNKKLSIIKNPSILINLIDNKEDYIIGKEIEQL
                     T"
     regulatory      56776..56868
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            56968..57762
                     /gene="thiD"
                     /locus_tag="KOU88_001862"
     CDS             56968..57762
                     /gene="thiD"
                     /locus_tag="KOU88_001862"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBK3211754.1"
                     /translation="MSNYKIPTLTIAGSDSSGGAGIQADLKTFSAIGTYGMSVITAIT
                     AQNTKGVFAVEDLNKKIIKKQIEAVFEDIPPRAVKIGMVSSPEIILEIVENLKKYNPK
                     YLVVDPVMISKSGYYLLKPEAKENLIKYLIPLAYIITPNIPEAEEITGIKIHNVDDMK
                     RVGEEILQLGPKFVLMKGGHLDGEAVDILVGKNIFKVYKSERIDKKNTHGTGCTLSSA
                     ITSYLALGYEITEAVNLSKIYITEAIKRSFDIGHGVGPVHHFYKFE"
     gene            57786..58574
                     /gene="thiM"
                     /locus_tag="KOU88_001863"
     CDS             57786..58574
                     /gene="thiM"
                     /locus_tag="KOU88_001863"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBK3211755.1"
                     /translation="MYNLIKDVKKLNPLVIHYTNNVTINDCANVTLAVGASPLMSFSY
                     EEVEEMVSVANSVVINIGTMNSNMLDLFLLAGKAANKYNKPVVLDPVGVFASKARAEL
                     TSRLLNEVKFSVVKGNVSEIKFIGGFNVRGKGVDSFDEEEDSTEIIRKIAEKLECVVV
                     ATGKIDIITNGKGTYKINNGTDKLKGITGTGCMTASLIASFMAVTENILEAATMGVLT
                     MSLSGELANLNNPPIGTFKENLMNAIYQMDIDTLSKNSNIEFLN"
     gene            58597..59229
                     /gene="thiE"
                     /locus_tag="KOU88_001864"
     CDS             58597..59229
                     /gene="thiE"
                     /locus_tag="KOU88_001864"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBK3211756.1"
                     /translation="MIDKESLKKCLKLYLVTDSEMLKGRDFYKCLEDAISSGITTVQL
                     REKNASGREFLRKAMKLREITKRYGVKFIINDRVDIALICDADGVHVGQSDIDVREVR
                     KLIGNNKILGVSARTLEEAICAKNDGADYLGVGSIFTTSTKLDAKSVSFETVKEIKEK
                     VDMPFVLIGGINLDNIDKLKCLESDGYAIISAILKAEDISKEVEKWTLKI"
     gene            59368..59670
                     /locus_tag="KOU88_001865"
     CDS             59368..59670
                     /locus_tag="KOU88_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3211757.1"
                     /translation="MIRILLVCVGGMSSTLLVNKMEKDAKKRNIDCKIWAVGEGDIKS
                     ELDNFDILLLGPQLRFMLDDVKSIVGDRAPVSIIDMVNYGTCNGHAVLNSVLEILK"
     gene            complement(59736..60485)
                     /locus_tag="KOU88_001866"
     CDS             complement(59736..60485)
                     /locus_tag="KOU88_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211758.1"
                     /translation="MLNILWRSMKWRFKNPISFVVTILQPFLWLVLYSSIANQTMNNI
                     NINNYTAFILPGIIVLVVFSSCSSGGIINFIMKNSGSFYRVLIAPISRYSIVLGQLLE
                     AILVSFIEVTILCIVSIFFSVRIESGIGGILLMIVLIFMTAFFLSSLAYSISLLLPNE
                     IVYETIMTAIVLPIFFLSSALFPIESLSGGLKVAVMLNPFTHVINALRSLIFGETILI
                     GDILPVILLFLILCCSSFSLAMWRLKKEMVS"
     gene            complement(60479..61441)
                     /locus_tag="KOU88_001867"
     CDS             complement(60479..61441)
                     /locus_tag="KOU88_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211759.1"
                     /translation="MLAIEIDNLVKEYKNGVKALNALSFNVNAGEIFSLLGPNGAGKS
                     SLINILTTFYKPTSGNVTMFGKDLVDNPSWIRTQIACVAQQISIDEHLSLMENMVFQS
                     KMYKVEPQIAKQRIDSLIDKFDLSSYLKYPTSSYSGGVKRRLDIAMNMVSSPKILFLD
                     EPTVGMDVDSRKSMWDMLLKIRDEYGTTIFLTTHYLEEAEQLSDNICIMKNGKDLAQG
                     TPSSLRSYIRQNILRITFHNTEDIKKYKDAIKSTGLVKFMSVRENSIFISVNDSRTAF
                     TLINKWLLEHDIEFDAIEIVEPSLEDVFLALTSSKKSLKEEWEC"
     gene            complement(61445..61903)
                     /locus_tag="KOU88_001868"
     CDS             complement(61445..61903)
                     /locus_tag="KOU88_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBK3211760.1"
                     /translation="MNCKIEIKNIESVTVATMRYNGPMTEATKYFPNVFKAIKGKSNG
                     APFFCYYDVDQKTGVAEMELCVPTAETPNRMGITTKEFPKTKALFFTHTGSYSNFPKT
                     YEMIFKYIHENNIKIQTPWREVFIKGPGMLIKGNPDNYITEIIFPLKEEE"
     gene            62258..62614
                     /locus_tag="KOU88_001869"
     CDS             62258..62614
                     /locus_tag="KOU88_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3211761.1"
                     /translation="MNFELDNTTPIYLQIVKYIKRQIVTGELKPGETIPSRREMALNL
                     KVNLNTVQRAYKEMGDMNIINTFKNYQSSVTVDENILKNLKLELINESLSVFIEDMKA
                     INVSKEEVLKIIEDKY"
     gene            62686..63402
                     /locus_tag="KOU88_001870"
     CDS             62686..63402
                     /locus_tag="KOU88_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211762.1"
                     /translation="MIEIKNVSKTYKRMQGLKIRKIEALKNVSFNIEKGKITALLGIN
                     GVGKSTMLKAIAGLINIDSGEIRIDGEKINEKVYNKLAFVPDVQSHFSNTTIKETFEF
                     MEIFYSKWNKEKSKEMMDIFKLDEDEIIDNLSKGNIARVKLILGFCQDPEYILLDEPF
                     TGIDLFKREEFIGVIAQYMEENQAIIITTHEIVEIESLVDEVVILDEGQIITSFNAEE
                     LREREGKSILDKMREVYKNE"
     gene            63395..64219
                     /locus_tag="KOU88_001871"
     CDS             63395..64219
                     /locus_tag="KOU88_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211763.1"
                     /translation="MNKLLYLINVDLRRSNKFYIAYISFFSLITLSLNLFEINKFKNS
                     KFIMNLAIEDFGGIFYGLGILSNLGFIQSILFFGILGLFIYYIFMWKREFFSNNQSIY
                     TLMMLPQNKFKICISKSIALITMIYGFLISQTATLFICKYIFNFIFRNMPIINMNFAK
                     DLYYLNLKSIPIDFISFMAIYVFLLLIAISIVNCCILFIFSYINKFYVILITLLIIAG
                     LYFSTIYINIITLFRKYYSLIGFQFNNLVAGLLSFLIIMFILNGISYLLIKKKVSL"
     gene            64231..65430
                     /locus_tag="KOU88_001872"
     CDS             64231..65430
                     /locus_tag="KOU88_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211764.1"
                     /translation="MKLKSKISILIIFLTLAIYFSIGLLNNEDNLKIKTIKGDSNELD
                     HININFGYALNGYINSYYTINGSNKTKKTELIKLQKDSKNTNNLIDVSSGSDLIAHVG
                     FEMNEESKDINFVIDEKKEDLEKGVFPSEGSDKEIEYEKLDMNNFTRTRYKVDKSTDD
                     YYANILASKRYKKYLYVSVLYATSDSSENNKEYSSTIDIIKINPENKKIKTIKSINLS
                     NYFSEKYQNIETIGVSYASKYEDKMYILVNVLNTNIGDNSNSKFHLLEYNLEENKESI
                     MELKTDSKMALAKAKLEANKLYMVMSNDYDNSSITELNLLTYNILDKSLDEDKYVLDN
                     REKRGIRSIEIDSNKIVAYTSRLNSILSWDNKFMLYIINKNSKEIVYEGELQFNSSNS
                     MLEFEIK"
     gene            65439..66251
                     /locus_tag="KOU88_001873"
     CDS             65439..66251
                     /locus_tag="KOU88_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211765.1"
                     /translation="MKDLIRLFEFELKRNIKNYIFIIICCCSFVILNIVKNLNDYNYI
                     IENAVKSEQLTKIGNTIETVKVTGFSSFRNIMGSTESWFMFGIIACICYSFFIWYRDF
                     NGRSKSIYTLIMLPKNRINIYISKLLNILFLVYSYTVVLTISLFIASKLLPRHMLGNV
                     TNYGFVQETIYELKMLLPYSFEILFVEYIFLLIGFVSVVFTSILINKSIYKVSTLISF
                     LFLVIEILVFIISIEFIIPYEYSDVFTVLYSSINIFVCSLISNKLLKQKIDF"
     gene            66262..67530
                     /locus_tag="KOU88_001874"
     CDS             66262..67530
                     /locus_tag="KOU88_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211766.1"
                     /translation="MKAKNIGKYTICFIIVCFLMITMTLILSYFNKDKLSVKTLKGNV
                     KDIGRVSVVYTPNISKFSYEEVIISKNGVRNNTNPKSRIRNDYLNIDKKYSDFVNDKG
                     KEFIYKDDLNIGEAYTSVKSDLVQGMNALNDCIKVSNKNLKSGVEENFDINLNKSDFK
                     ENSWKTLFNKIYKGNLYMVISETNISGSKVNNICILKIDIKNKSYKLLNRFNLGLQNG
                     EQQNINEIKFSIGSKLYLEIVNNKSKNGYIEGHDSYSNFIIYDIEDNTFNISNKFMDN
                     LNKEKNANPKEIGLLSKTKLDYMVKNNKLNLIVTDMSNSITNLVYDINSNEIKLEDYE
                     ILDLKVDYNEASSGVRKVKLLDDKIYSISGIKNSISGELKGFKGIVDVVGTKPVKFQV
                     FDMKLKKNIYEAELINGDISLQEKLFFVAN"
     gene            67896..69077
                     /locus_tag="KOU88_001875"
     CDS             67896..69077
                     /locus_tag="KOU88_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBK3211767.1"
                     /translation="MNKKYIKAGNLIDGTGNSIMQNKGIIIDGDTIVEIEDIRDDLNG
                     YDVYDYLDKTVMPGIMNCHVHLTMEPVGNPKIYYDNVSDVELVVNTIKQLDAYLDSGV
                     TYIRSLGCPKYVDVQLKNLIDKGSIDGPGIVTSGPVICMTGGHGYYFGIESDGVDECR
                     KSARTVLKNGVDCVKIMATGGVTTDGVEPGSPQLTLEEMKAAVDEAIKAGKITATHAQ
                     GRTGIKNAVLAGITSIEHGVYLDDEIIDLMLERGTYLVPTVAAPYFILNAGKESGITE
                     ATLRKCEIVAIPHKESFLKAYKKGIKIAVGSDAGTSYNEHGKTYYEMKLMSDYGMDNM
                     DIIVAATKTASELLRIDKNYGTLEKGKKADVIVVNGNPVENIDVLADVLAVFKLGKKV
                     R"
     gene            complement(69219..70136)
                     /locus_tag="KOU88_001876"
     CDS             complement(69219..70136)
                     /locus_tag="KOU88_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211768.1"
                     /translation="MENNKCREDFRFTQEYEEDYPNTNERYYENYQVADRYYNYPNKY
                     KEPKIKQCCCKKSMREALELLRYDALRPFVNFNQFAFISDFFIVGANLVGIDLSAPPK
                     DNLSGLDGTFERFSACNCDLIDIAGRVSYPIPVPLTLEGLINTIGTIPGVAELIALID
                     AVIPPTIDLGAILDAILAAIIDFILAASTPLANVDLASLCNLKAVAFDITPADYEDFI
                     ASLGYYLDKKHYKECNCNCDCDDCCCNKGILDNLYMSNINNQVTVVAGSLVLTGVEVL
                     GKKNDVIVLGNSNDSRIYFVCVDSIDYIA"
     gene            70389..71183
                     /locus_tag="KOU88_001877"
     CDS             70389..71183
                     /locus_tag="KOU88_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211769.1"
                     /translation="MIEVDKLCKSFTRVVKDDKNKSSIRKLKKVKTKKEEFFAVNNVS
                     FKVMEGEIVGILGPNGAGKTTLLRMLGGILTPTSGSINISGYDYSIDRNSAKKEIGYL
                     SGNTKLYGRLSPRELLTTFASLYEMSKEDIEESIENIVKIMDMSEFIDNRIENLSTGQ
                     TQRTSIARCLIHSPKVYIFDEPTLGLDVLSSASIIDFMKNEKLRGKTVLYSTHYMEEA
                     ETLCDKIFMIHNGKIIASGTPQSLKEESGVNNLRDVFIKLARKEDI"
     gene            71184..73244
                     /locus_tag="KOU88_001878"
     CDS             71184..73244
                     /locus_tag="KOU88_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK3211770.1"
                     /translation="MRSKIVKYIFKKEMLDILRDKKTLFMMIVVPLLLYPLLMLLMIQ
                     VMNMSASSMNSKDINIAFNNKPNKVLVSMIEDDNLEKDTKNTSNDKGKIRVLDVDNYK
                     KSLEENKIDAYIKMEEKKSSINYQIYINSSQENSSNALKRIETVLDKYKRFTIEKTLS
                     EKGLDVQATLEPITYSTVDVAKTEEVAGYFLGQILPFILIIGVLLGSIYPAIDVMAGE
                     KERGTLETLFTLPISNLELVMGKYMAVSLSAIVTAILNILSMGLTMAFILVSGGISSQ
                     FGFGNFNYGDLVLPIITTLICICLFSMVVSAISMCVCSLAKSFKDAQNYITPLMLIIM
                     IPSYVSMIPNIVLDRVTAVIPVVNISLLIKSVLSFKSDLNLIALVLASNVAFVILAII
                     LLSKMFNSEEILFGNSKSFSFLEKRSNIKKGSIPTVSDGVILYAVGLVLLIYVGSLVQ
                     IKFGMAGIIMTQFMIISLPLLFAYYIKADFKEVFSLTVPKLKHVFGSIVLWIGGYILI
                     MIITQLILFLFPQNMEVAESLNKALFIKDSVLLNLLAIALLPAICEEMFFRGFIFSSF
                     SKSKDKNKSIKLAIICSGVLFGIMHMDFIRIIPTSILGIIFAYSVYKSGSIFVSMLLH
                     FLNNSVAVVLNHYTTGNITNLYKFVEVDFSNLNVLKFALILLISLILIMLGLRVLDRK
                     SLRN"
BASE COUNT        29126 a         7501 c        12734 g        24168 t
ORIGIN      
        1 aaaagggaaa tagataaact ttttttggat gaagaatatt ttcaaataga accacaatta
       61 tttgaagaat atgatgaatt tacaactata aataataaaa ttccagaaga atctatggta
      121 aaggttgtaa atggaaaagt aatggtactt agagctgata taactacaag tataataaaa
      181 agccttgtac caagatggga agatggttta aagcttaagc ttttttataa ttcatcaata
      241 tataaaaata aaaatacagt tggaataaaa gagataagac aaataggttg tgagtatcta
      301 ggagaagcct ctgtagaagc agatagagaa gtagtgaaat tagctcttaa gatacttgaa
      361 aaatacaata ataattttat tctagaggtt gggagtagca agtatattca tggtttgtta
      421 gaagaattaa atttaaataa gaattgtgaa aatcaaatta aaaatttact atatacgaag
      481 aacactcatg aattaaaagt atatattgaa gaattaaaaa ttaagcgtga agtaaaagag
      541 ttattatcaa atattttaag tttacaaggg aatttatata atgttattga aaaatcaaac
      601 aagttctatt gtaataataa gatgaagcaa gctcttgaag aattaaagca agtaaataat
      661 ttgattgagg aatgtaattt tttagataag gctagatttg atttatcaat gattactatg
      721 cttgactatt atgaaggaat tatgtttaga ggatactacc caaactcata taaagaaatt
      781 cttagtggtg gaagatatga ttctttaact aaagagtatg gaaaagaaat tccagccatt
      841 ggatttacac taagtgttga tgagttaatg aagtatgtat ataagtaaag tttagaagga
      901 gggattgctt tggattattt gactatagca ctagcaaaag gacgaattga aggggaatca
      961 tttaaaaaat ttaaaaaaat gggtctagga gatagtatag acacagatac gagaaaacta
     1021 atttttaaag atgaagaaaa taaaattata tatatacatg taaagccatc agatgtagtt
     1081 acatatgttg aaaaaggagt cgctgacctc ggtatagcag gtaaagatac tattttagag
     1141 aatgagacag atgtatatga aatatatgat ttaggttttg gaaaatgtaa atttgctgta
     1201 gcaggattaa agggagatag catatataga gaagatgaat atttaaaagt ggcaacaaag
     1261 tatcccaata tagcaaaaaa gtattttaaa gagaaaggtc aaaaaattga aataataaaa
     1321 ttaaatggtt ctgtagaact agctccaata gtagggttgt cagatgtaat tgtagatata
     1381 gttgagactg gcaatacact taaagcaaat ggtcttgaaa tattagaaga catatgtaat
     1441 ataagtgcta gaattatatc aaatagagct agctatagat ttaaatatga acaaattcag
     1501 aatataattc gtttatttga agaacttgat aattaaaata taattgagct ttataaggag
     1561 ggatttaagt tgagagaaaa agaaagcata agagagttaa ggggatatga accaaatcac
     1621 gtaaactgta aagtaaaact tgatgcaaat gaaggaagta agaggttgtt taaatacctt
     1681 attaaagaaa tttcagatag tgatatagat ttaaatttat atcctgaaga ttcttatagt
     1741 gatttgaaag aatctataat agattacata aatatttctg gagtaaataa gaaaaatctt
     1801 ctagtaggaa acggttcaag tgaaataatt gatttaataa tacatacttt tgtagataaa
     1861 gatgaagtaa tattgagttt ctctccaagt tttagtatgt attctatata tagtcagata
     1921 aatgggtcta aatttatagg tgttgaaagt gatgaaaatt tagttataaa tatagataat
     1981 gtgattgaaa aagtaaagga gaataatcct aaaatagtaa ttgtatgtaa ccctaataat
     2041 ccaactggaa caatattaaa gagggaagag ataataaagc ttttagattc aactaatagt
     2101 ctagtggttt tagatgaagc atatatggat tttggagaag aaagcatgtt aagtgatgtt
     2161 tttaagtatg ataatctaat agttcttaga actttatcaa aggcatttgg attggctgga
     2221 ataagaacag gatatatgtt atctaatagt agtttaataa attctgttga gaaagtaaga
     2281 cctccatata atttaaattc attatcagac tttattgcta caagagcact tagaaataaa
     2341 gatgtggtaa aggcttatat aaaggaagta aaagaggaaa gagaagtttt atatgaagaa
     2401 atgattggta tgggaattaa agcatacaaa tcacaagcaa attttatatt attttattct
     2461 gaaatcgaaa atttatcaca aaaacttatt gatagaggag ttttaataag aaaatttggt
     2521 ggaaagttag aaaattatta cagagttaca attggtgata aagaagaaaa ttctatgttt
     2581 gttggagcta taagagatat tttgaaaaag gagaaatagg tatgagaatt tggaaggtag
     2641 aaagaaatac tcttgaaaca cagattttag tagaattaaa tattgatggt tctggtaaag
     2701 ctgaaataga tactggaata ggatttttag accatatgct taccttaatg tcatttcatg
     2761 gcaagttcga tttaaaagtg atttgtaagg gtgatacata tgtagatgac caccatagtg
     2821 tagaagatat aggtatagct ataggtgaag catttaaaaa tgctctaggt gacaaaaaag
     2881 gaatacgaag atattctaat atctatatac ctatggatga atctctatca atggtagcaa
     2941 tagatataag caatagacct tatcttgtat ttaatgctaa atttgatacc caaatgattg
     3001 gtagtatgag tactcaatgc tttaaagaat tttttagagc ttttgtaaat gaatcgagag
     3061 taacattaca tatcaatctc ttatatgggg aaaatgacca tcataagata gaaagtattt
     3121 ttaaagcatt tgcaagagct ttaaaagagg gtagtgaaat agtttctaat gagatagcat
     3181 cttcaaaggg ggttttgtag aatgaatata atagtagact atggtcttgg aaatatagat
     3241 tctgtgtcta ggggttttag aaaagctgga atagaaacta aaatttctag tgatatagat
     3301 gaaataaaac aggcagattc acttatactt ccaggtgttg gagcttttag agattctata
     3361 agtgccttag ataaactagg attgatacca ataataaagg agcatgtttc taagggtaaa
     3421 tttatgatag gtatatgtct aggaatgcaa ttactttatg aaaaaagtta tgagtatgga
     3481 gaatatgaag gattaggact tataaaagga agtattgata aactggatat aagtttaaaa
     3541 gtgccacata tgggatggaa taatctaaaa tttaataagg caaatgatga tatacttaaa
     3601 tatataaatg aagatgatta tgtatacttc gttcactcat attatgcaaa ttcatcaaat
     3661 gaagaactaa ttgcattttc agaatatgaa aagaaaatcc ctgctattgt tagaaaaggc
     3721 aatgtatatg gtatacaatt tcatcctgaa aaaagtggag aagtagggtt aaatatatta
     3781 agagcatatg gggagatgat aaaatgataa tatttccagc aatagatata aaagataata
     3841 agtgtgtaag actcacacaa ggagaatttg acaaagtaaa tgtatattat gataatccat
     3901 tagaagtagc atataaatgg aaaaatgaag gagcagaata tatacatata gtagatttaa
     3961 atggtgctag aagtgaattt ggtgtaaata caaaaataat tgaggacata gcaaacaata
     4021 tagatatacc tattcaagtt ggcggtggag ttagggataa ggaaaaagtc aaaagtttaa
     4081 taaatgctgg tgttactaga gtaatattag gcagtatagc gattgaaaat ttgaatttag
     4141 ttgaagaatt ggtcaatgaa tataaagaga aaattgtagt ttctatagat gctaaagatg
     4201 gaaaagtagc agttagggga tgggaagttg taagcaatgt agactcatta acattatgta
     4261 aacaacttga aaagataggt gtacaaacta ttgtttatac agatatatca aaagatggga
     4321 tgttgcaagg tccaaatttt gacatatatg aaagaatagc aaaggaaaca tcactaaatg
     4381 ttattgcttc tggaggcgta acttctatag aagacgtaaa aagactaaaa gctatgaact
     4441 tatatggtgc aataataggt aaagcgcttt atgataaaaa gatagacttt aaggaggcac
     4501 aacaattatg cttactagga gaataatacc ttgtctagat gtgagaaatg gaagagttgt
     4561 aaaggggaaa aaatttaaag atatagtaga tgttgatagt ccagaagtac ttggaaaatt
     4621 ttatagtgat tgtggtgcag atgaacttgt attctatgat ataactgcat caaatgaaga
     4681 gagaaagaca tctttagaat ttgtgacaaa agttgcagaa aatataaata taccattttg
     4741 tgttggtgga ggagtaaata aattagaaga tttcactgat attttaagaa aaggtgctga
     4801 taaagtttct ataaattcat cagcagtcaa aaatcctgaa ttaataaggg aagcttcatt
     4861 aaaatttgga gcacaatgtg ttgttttatc gatagatgca aagaaaaatg aagagggttc
     4921 atggagcgta tacgtaaaag gtggaagaga aaaaactaat ctggatgcaa ttgaatgggc
     4981 tgttaaaggt gtagaacttg gagcaggaga aatcgttgta aatagtatgg atgaagatgg
     5041 aatgaaaaat ggatatgata tagaattatt atcaaagata acttctttag taaatgtacc
     5101 tgttatagca tctggaggcg ctggaaaaaa ggaagatttt tatgaggcgg ttaataaatc
     5161 caatgtagat ggaattttag cagcatctgt ttttcatttt ggcgagataa aaataaacga
     5221 tttaaagaaa tatttaaaag acatgggtgt agaagtaaga ttataagtta aatactaaaa
     5281 ggagattaga aatatggata ataagtgtaa caatgtatac agtgatgaag tagagaaatt
     5341 tataagaagt ataaagtttg atgataaagg gttagtccct gttgttgttc aagaggtagt
     5401 tagcaaagat gtactgatgt tagcatatat gaataaagat gctataaaga aaaccttaaa
     5461 agataaagta gcttgctatt ttagtagaag tagacaagaa ctttgggtta aaggtgagac
     5521 atctggtaat actcaaaaag tagttaagat gtcttatgat tgtgatgtag atactatact
     5581 actttttgtt gaacaaactg gtgtagcttg tcatacaggc aattattctt gtttttacag
     5641 agacttgttt gatgatagtt caaaaatgga gcttgaagta caaacaaata tattgaaaga
     5701 attatatgat ttaatcaatg aaagaaaaaa taatccagtt gaaggttctt atactaatta
     5761 tctttttgaa aaaggaatag ataagattct taaaaaagta ggtgaagaga gtagtgaggt
     5821 aattatagca tcaaaaaata ccgataaaag tgaacttatt tacgaaatta gcgatttagt
     5881 atatcataca ttggttttaa tgatagaaaa aggtgttgaa attgatgaaa taaaaaaaga
     5941 attacttaaa agaagaaaat agaataagat agattaatgg gtaataagaa aatataccgc
     6001 ttttaataaa aagtggtata ttttttattt tatattttga tttatagaat aatatttaaa
     6061 ttacttgata aaattaacta tatatataat ttattgataa aataattcta gtacattatt
     6121 tattttagaa aaaagataat tatctaatta tatttaagga taataatatg aaaataattt
     6181 ttatattaaa aaatatgaat gaaaatagtg ggttttataa aaaaacatat ttagatttta
     6241 acatctcaaa ggagttttca aagctaatat ttcattttta aataaaaaaa taaaatatta
     6301 gttttgattt ctggtttaaa ttgggttata ataaattgtc aaattattta ttaatataaa
     6361 atagactata aaacaagcaa aaatcatact attatataaa agaccttaaa gatagaaaac
     6421 tacagaaaga agccaaaatg tttttgaaaa aaatgaaatt ttattgcaaa aaaatcaaaa
     6481 tgaatttaac ttaatagtta taatctattt ttagtgttat aaatatacaa tgtatattat
     6541 acaatataaa aaatacattt acttagaagt attattatat ttggattttt ggtttttata
     6601 atttttttat atttaaacat aactaaaaat aaaagattac taaagctaag tagagtttat
     6661 tttattttaa taaataataa agctattttt ctatatattg gcataatata tgcttattta
     6721 actatgaaat taaaattaaa taggattaat gaggaggaaa aaaatgggaa gtaatgaact
     6781 aaaaaagact cttggcgtat cagcagcatt atcaactgtt gttggttccg ttataggagc
     6841 gggcgtattt tttaaaccac aagcagtcta tacattaact ggaggagctc caggtcttgg
     6901 tatattggca tggttaatag ctggaatcat aactataaca gctggtctta cagctgcaga
     6961 ggtatcagtt gcgataccaa aaactggtgg aatgatggta tatataaaag aaatttatgg
     7021 agaaaaatta ggttttttaa ctggatggat gcaaattgta ttattttatc cagggatgat
     7081 ggcagcatta ggtgttatat ttggagaaca agcatcagca ctaattggta gtccatcact
     7141 tttacttcca atagcaattg gaattatagt aatagttgca gggcttaata tgttaggttc
     7201 aaaaactgga ggagtcatac aaactgtttc tacaatttgt aagttaatac cacttatttt
     7261 aataatggtt gttggattta ttaaaggtgg tggaaataat ccaatactta cacctatggt
     7321 tggtgaagga ttaagcctgg gtagtgtact aggtcaagtt ttaattgcta tattatttgc
     7381 ttttgatgga tggatgaatg ttggtacttt agctggagaa atgaagaatc ctggaaaaga
     7441 ccttccaaaa gctataatag gtggattgtc agttgttatg gctgtttatt ttataataaa
     7501 tttagcgtat ctttgggtat taccagctaa tgaattagca aattatgctt ctcctgcatc
     7561 agcagttgct gaagttatat ttggttcaat gggtggaaaa ataatatctg taggtatatt
     7621 aatttcagtg tttggagcat taaatggatt tttactaact ggttcaaggg tggcatatac
     7681 tttagctaca gataagactt taccaaagta tggtatattt tctaaattaa attctgctca
     7741 agttccagca aatgcaatag cattagtatc tgttattgca tctatatatg ctttgtcagg
     7801 tcaatttaat ttattaactg acttagctgt atttgctact tggatattct atgtattaac
     7861 ttttataggg gttatgaaac ttagaaagac tcatccaaat ataccaagag agtataaagt
     7921 tccattatat cctattgttc ctataatagc tatagcaagt ggtatatttg ttgtagttaa
     7981 tcaattgtgt tttgcaggta tgaaaactac tatgatatct ataggaggtc ttgtaataac
     8041 agctataggc ttaccagtgt atgcttatat gactagagga gtaaaaagat aaaccaagta
     8101 gtttacaaat gcttcataat taaaataaaa gagactgtct caaatagaga taagtctctt
     8161 ttttattgtt aaaatggtaa agatatgttt gattttacaa aaaaagagcg ttccatgaac
     8221 taaaaagttt attttaaggt attcatttta tttttagttt tttgattata aaattaaaca
     8281 tctaaaaaat tatttatttt aaaatacttt attttaaagt gttttttatc aaactaagtg
     8341 gtatctgtac aacaaatatt atacatagct tttatgaaaa ttaaatcttt ctgttatata
     8401 taatagaata ttgtattata tagaaaatat tacctgatta atatagtgat ttataaatga
     8461 gattagaaaa ttttatttga taacaaaaat tagatagtat gaatatataa tgtatgtatt
     8521 aaaaatgtgg caaatagttg ttttgctatt tattatttgt ttaatatttc taatttataa
     8581 aaaaaaaatt ataaatttta aaaattataa atgacatttt aactagaatt aattgtaaaa
     8641 aacactatat aatactcaat tttcaacatt ctatacaatt atacagaaat tatacagcat
     8701 aataatcacc gaaataacaa attttaaaaa ttaagcaaaa ctttttgtcg aagttcaacg
     8761 tctatatata tgtagtgtaa atttttggga taaaatacta caaaaatata aatgtaaaaa
     8821 tatagtaata ttggaggtcg aacgatgaga aataaaaaga aaaaaataaa tagaaagaag
     8881 ttgtatttgc ttttaagtgc tattgtagtg tgtctggctt ttatagtagt tggtgttcgc
     8941 gtcagctctt taaatatgaa ggaaaatgaa attagtagaa atgcaaaact gtcaagttct
     9001 actattacag atatagtatc taatacatca atagaagtta gtaaagggcc aagtaaaagt
     9061 tctggaaaaa tagcatacat aactatagat gatggtccat ctaaatttac tgacgagatg
     9121 ataaaaactt taaataaata caatgttaaa gcaacttttt ttatgataga tgggaatatg
     9181 aaggaatatc cacagcaagt taaaaatata attaaaaatg ggaacacagc gggttttcat
     9241 agtgtatcac atgatattca caagctttat gttactagta catcagcaaa agaggaattt
     9301 gatacaaatg atcaaacttt ttataagata actggtaaac attcaaaagt aataagaata
     9361 ccttatggaa gcaaaccata tacaccacaa gcctcttatc aggctttagt tgatgctgga
     9421 tataaaattt gggactggga cttagataca gaagactgga gatctaattc ttctcaaatt
     9481 gtacaaaatg taaaaaatca tattaagaat agaaaaggtg aagataaaga ccaacttgta
     9541 gttttaatgc atgagaaaaa acagagtgca gaagctctag attcagtttt aaaattctta
     9601 tcagatgaag gttatgaatt tgcgccagta gatcaaaacc aaataccaaa aaattattgg
     9661 ttacgtaatt tagagtagtt aaaatataag aatattgatt gatattttta gaaattgaga
     9721 ataaaaatga gtgaggtgta ggtatattga ataaaaaaat ttatatagga atggtcggaa
     9781 tattgtcttt gatgatggtt ggttgtaata aaagtttagc aaaagtaaat gatgtggaaa
     9841 tcacaaaaga acagtacaaa aaaacaaaag cagttttatc tgctactaat aattatataa
     9901 atgggcagtc tttagatgaa ttagaaaaaa ctttggataa aaaaggtaga aataaattag
     9961 aaaatgttat aatatcgttt atggtggata atgaactttt atatcaagag gctaaggata
    10021 aaggactaac tccaagtaaa agtgaagtag actcaaaata tcaagaacta gaagataaga
    10081 tgaatttgaa tacaagctat aaggaaaaaa tggacaaagc aggtgttgat aaagattatt
    10141 taaaacaaga aatatctaga gatttagcaa tagataaaaa taaaaaggcc tttgaagata
    10201 gaataaacat aagtgataat gatatggaag cctactatac aagtcataaa aaagatttta
    10261 atgtagaaga agtaagtgct tctcagatac ttatatcgac tttagataaa aataaaaaag
    10321 aagtaagcaa agataaaaaa gaagctttga agaagaaggc agataatata ttgactaaaa
    10381 tcaaaaatgg agaaagtttt gaaagtttgg ctaaaaaata ttcggatgat aaagcaactg
    10441 gaaaaaatgg aggacagcta ggatatttta caaaggatga taaaaatgct gagtttacaa
    10501 aggaagtgtt caaattaaag aaaaatgaag tttcaaatgt gtttgaaact agttatggat
    10561 atcatatagt caaagttact gataaaagag aaagacaaaa aagttttaat gagtgtcaga
    10621 gtttaataag agaatctatt ttaaatgaaa agtatattga gcatataaaa aaactgaatg
    10681 aagatgctaa aatagacaga tagaatttct aacagctcaa tcctagcctg taatcggagg
    10741 gagattttac aggaatgttt aagagtttaa agagaacgaa agttgagaaa tacattatcg
    10801 ataataaaga ctctttttat agaatagcat atagttatac gaagaatgaa gaagatgcct
    10861 tagatgtggt tcaagaatcc atgtataagg cactatactc agtggaaaat attaaagaag
    10921 taaattatat aaagacatgg ttttataaaa ttttagttag aacgagtata gattttatta
    10981 gaaaaaaccg taaatataat aatatgacag atattgacct tatagatgag actggagagt
    11041 atgataaata tactgatttg gatttaagaa gagctttgga agaattacct attgaataca
    11101 aatctattat aatattaaga ttttttgaag atttaaagat tgaagaagta gcaataatat
    11161 tggatgaaaa tgtgaatact gttaaaacta ggttatatac tgctttaaaa aaactaaaat
    11221 taaaaattga agagtaggga taaaaagaat gacaagcaaa gaaaggttaa ataagttaaa
    11281 agatgagtat cataaaattc caatacccaa gaaattagat actataataa atcatgaaaa
    11341 aatagaaaac atatatcgag agaaaaataa aaaagtaaat agattaagat ttaaagttgc
    11401 aatagccttt gcatgtatat ttacagtatt agtaaatata agtcctgtat ttgcagacaa
    11461 tttttctaag atacctgtaa ttagagcaat agtagaagta ataactataa aaaattatag
    11521 tttaaaaagt gaaaattatg aagctgagat tgatattcct aaaatacgag gtttaaaaga
    11581 taaaaactta gaacaaagat taaacagtag ttttatggaa gatggaaaaa gactttatca
    11641 tcaattccaa gagagaatgg agaagataca atcatcaaag aataaaggat ataaatcttt
    11701 aagtttgagt tatagtgtaa aaaataattc taaaaaattt ctatcaatag agatgacaaa
    11761 aaatgagata gaggcttcat catatgtgag taaggtacat tatactattg ataaaaaaag
    11821 acaaatagtt ttgactttgc caatgctttt taaagatgat aagtatataa aagttataag
    11881 tgataatata aaagaacaaa tgagagaaca aatgaaaaag gatagtacaa aatcctattt
    11941 tatagatcaa aaaaaagact tgcctgttga agattttaaa acaattaata agtatcagga
    12001 tttttatttt aataaaaatg aagaccttgt aatttgtttt gatgaatatg aagtagcacc
    12061 tggttatatg ggcgcagttg agtttgtaat accatataaa gtaataaaag atttgtaaat
    12121 tgaatagtag tttatatata aatcttttaa ggaggagaat atgactacat ataaaaaact
    12181 taaaaaatct atatttaaaa ttgctatatt ttcaatatgc ttattagttt cattagtaga
    12241 tacaaaccct atatttgcag gtagttcctt taatgaaact tcaaatagtg atacgataaa
    12301 ggtgttaaat gctaagagta tcaactttaa acaagacaat tatgaagtga atgtgagtat
    12361 tcctaaaata aaaggtttaa aagataaaac tttagagaat aaattaaaca atgagctttt
    12421 gcaagatggg aaaaaaattt acagtgaatt tcaaaataaa atgaaaaagg aagataataa
    12481 gggtcataga tacctaaatg taatccataa tgtcaaaaat aattctaagg actttttatc
    12541 aatagaaatg acaaaagaag agatagaagc ttcctcatct ataactaaga agcattacac
    12601 tgttaataaa aatagaggaa tactattaaa tttaccaata ttttttaaag atagtagata
    12661 tattagagct ataagtgata atataaaaga gcagatgaga aatcaaatta agaaagatga
    12721 tacaaaatct tattttatag accaagataa agactcgcca gtgaaagatt ttgaatctat
    12781 aaataagtat caagattttt attttaataa aaatggaaat cttgtgatta gttttgatga
    12841 atatgaagta gctcctggtt atatgggagc agtagaattt gtgataccaa ataaagtaat
    12901 aaaaagacta agatagatat atagaagatt tttagataga ctggtaagga gaattatatg
    12961 aatatatatg aacaagcaat aagattaata gaaaataatg aggatttcgc atttgctaca
    13021 ataacgtctc attcaggttc aacaccacgt gaaactggag caatgatgat tgtgaaaaat
    13081 gattctacta tatttggctc agtaggagga ggtagtgtag aagcagaatg tataaaacat
    13141 gcaattaatg ttataaaaaa cagagaatca atgttgtata aatttactct aaacaaatct
    13201 gatgttgcaa aactaggaat gatatgtgga ggtactggag aaatacaaat agattttata
    13261 gatagtaaat taaaaagtaa tatagaaaaa tttaataaga gactaaagga aaatacaagt
    13321 aaagcatata tatttggtgc aggtcatatt tcaagagatg ttgctgtgat actatctctt
    13381 ttagaattta gaacagtagt aatagatgat agagaagaat ttgctaatca tgaaaggttt
    13441 ccagaatcag aagtagtagt tttagattct tttgaaaaca taccagattt tccaactgac
    13501 gaaaatagtt atataattat tttaacaaga ggtcatctat atgattcaag tgctttagaa
    13561 tgggctctta aaagagaggc tggttatata ggtatgattg gaagtagaac aaaaattgga
    13621 ttgacttacg aaaaactcat gaaaaaaggt tttaagaagg aagaattatc aaaagtacat
    13681 gcaccaatag gcataaaatt gaatgctcaa acaccagctg aaatagctgt atgtatagct
    13741 gctgaactta taaattgtag agctaataag gaaaaataaa ctaatgaaca cagggagtaa
    13801 agatattgat actttaaagg ttaattttag agggattgaa ataaaagcag ttttagtata
    13861 taaaaataga aaaaatattt ctataaaaat aaatccattt ggcaaaataa ctgtaatgag
    13921 tcctcctaaa atatccaaaa aaataataaa agatataatt attgaaaaag gagactggat
    13981 acttaaaaag tcagaaaaat gtaaaggaag agaggaagta tataaacaaa gaatgtttat
    14041 aactggcgaa aaatttcttt atttaggtga agagtaccat ctagttataa aagaactgtt
    14101 gagagattct gtcaaaaaaa gtaactgtag aataactatt aacgaatatc aaatatttgt
    14161 tcagacaaat gatacaagta cagattttat taaaaaatct ttaaaatctt ggtataagat
    14221 ggaaagtgaa agaatagtat tagagagaat agattttctt aaattaaatt gtgaaataat
    14281 gaagcaatta gttccagcga gtgttaaggt aaaagaacaa aataagagat ggggaagttg
    14341 tacagctcaa aaaaatattt atataaactc aaaaatatct atggcaagat tagatgtaat
    14401 tgattatgta ataatacatg agtttagcca tttagtacat atgaatcact ctaaaaaatt
    14461 ctatgattta gtaaaatcca ttatgcccga ttataaagat aaagaaaatt ggctaaaaat
    14521 aaatggatat aaaataataa tctgaaaacg attattccaa aatataggcg taaagtataa
    14581 aagaagtatt attgtgaaaa aaataaataa tctgaaaatt ttaaaaaaag tcattgacat
    14641 tgtaaatgat agggaatata atctatatta acaacaaaac agaattaaaa tataaaatta
    14701 aaaaattaaa agcaatgaca gagacaacaa tactaatagt gttatccaca gagaaccaat
    14761 gttgctgaga attggtgtta acagtagtat aatgatcact ctggagcttt tgtactgaat
    14821 atttttagta agtacaaacg tatgtcaacg ttacatgact aaggttaagg taattaatta
    14881 cccgacctga aaaaagaggg gtagatgtat tttttatatc tacaaataag gtggtaccgc
    14941 ggaatataac tttcgtcctt ataagtaata tttatattgc ttataaagat gaaagttttt
    15001 ttattttaag cgatataaat aaatttaatc catataaaat taataaaaaa ataataaaaa
    15061 taaggaggga tttttatgga aaatactgta tatgctaaat taaaccaagg aatagattct
    15121 tttttaagag tggctatgac tctaagaaga agagaggttg atatacaatc aataagtatg
    15181 actgtagata atatgaataa ttcaggtata aaattaatag taaatgaaga aaagacatct
    15241 ttagattctg tcttaaacca tatgaaaaaa ctacatgata taagagagat aactgttgaa
    15301 agaatgagac attaattaaa tatattttat aaaactaaag ataaatatgc ttattttaaa
    15361 ataaaaaact aaagataaat attaaataag aaaaatctta gattaaaata taagtgtcat
    15421 tgaatttatt agtttatcac agttaataaa tttattagtt tgttgtagct aataaaaact
    15481 gaaaattcta aaattataat tgtaagatta tataaattta gaatttaaat ctgttgaata
    15541 atattaaaac aatgataatg agtatgaatt tctaataaaa ataaatatca taaaaataag
    15601 aaaaagtatt gggaggaaat gaaaatggca agaatgtatt atgaaaaaga tgtggattta
    15661 gaggttttaa aaaataaaaa ggttgcagtt ttaggttatg gaagtcaagg acatgcacat
    15721 gcacaaaatc ttagagataa cggtgtacat gtaatgatag gtctttatga cggaagtaaa
    15781 tcagcacaaa aagcaaaaga agatggattt gaagttaaga gtgtagcaga agctacaaaa
    15841 gaaagtgatt tgacaatgat gttaatgcct gatgaaaaac aaaagaaagt ttatgaagag
    15901 agtgtaaagg ataacttaaa agaaggtcag acattagctt ttgctcatgg attcaatata
    15961 cattataatc aagtacaacc accagaattt gttgatgttg taatggtagc tcctaaagga
    16021 cctggtcact tagttagaaa tgtatttaca aagggaagtg gagttcctgc actatttgca
    16081 gtatatcaag accacactaa aaaagctaca gagacagttt tagcatatgc aaaagggata
    16141 ggagcaacaa gagcaggtgt tttagaaact acttttaaag aagaaacaga aacagattta
    16201 tttggagaac aatcagtact ttgtggtgga ataagtgaac ttataaaatt gggatataaa
    16261 acgcttgtag atgcaggtta tcaaaaagaa gtagcatatt ttgaatgttt acatgaaatg
    16321 aaactaatag tcgaccttat atatgaaggt ggatttgaaa gaatgagata tagtataagt
    16381 gacacagcag aatatggaga ttatgtatct ggtaaaagag taataactga tgctgcaaaa
    16441 caaggtatgc aaaatgtttt agaggatata caaaatggaa aatttgcaaa agcgtggatt
    16501 aaagaaaatg aagaaggacg tgaaaacttc ctaaaaacta gagaagaaga atataataca
    16561 gaaattgctg aagttggtag aaatctaaga agtatgatgt cattcttaaa ataaatatat
    16621 attaaatgga ttagtttgag ggaaagagtg gtgtatagta gtgcgtatga atggagcaaa
    16681 ggtaatttta gaatgtttaa agaaagaggg aattgacaca atatttggat atcctggtgg
    16741 agccgtgata cctctttatg atgctctata cgattattca gatgatttta aacatataag
    16801 gacatcccat gaacaaggtt tagttcatgc tgcagatggg tacgcaagaa gtactaatac
    16861 agtaggagtt tgttttacaa catctggtcc aggagcaaca aatgccataa ctggaatagc
    16921 aacagctttt atggattctt cacctatggt tgtaatttca gggcaggtgc caactagttt
    16981 attaggaaaa gattcttttc aagaaattga cataactgga gcaacattat ctatgacaaa
    17041 acataattat ttagttagaa acactaaaga attagttcct acaataaaag aagcttttag
    17101 agttgcaaat tcaggtagaa aaggacctgt acttgtagat gttccaaaag atttattttt
    17161 agcagaaatg gattttagtg gtgaggacta tgatttatgt caaatagatg attatatgga
    17221 ttataagagt gattttgatc tagatgatga aactaatatt aagcttttaa atgaagcaat
    17281 agatatcata aaagaatcta aaaagcctgt aatatatgca ggtggaggtg ttaaatcttc
    17341 agacagtgag gaaattcttg aaaaatttgc aactaagata gatacacccg tactaaatac
    17401 acttatgggg cttggaaata tagatagaaa gaatgaacta tctcttggaa tggttggaat
    17461 gcatggaagt agagaaagta atttagcact ttctaattca gatttagtaa tagcgatagg
    17521 tgcgagattt agtgatagag tgataagtaa aagttctgaa tttgctaaaa atgcaaaaat
    17581 aatacacata gacatagacc catctgaaat aagtaaaaat atagaatcta atgtatcttt
    17641 ggttggagat gtaaagctag tccttagttt attaattgaa agggttgaaa gtaagaataa
    17701 tagcaattgg aaagaagaga taaagagatt tagaaagagt gagggtgtac aaacatatga
    17761 atttcatcca caaaatatac ttaaaaaaat aaatgaaaaa tatgaaacat taaagaaacc
    17821 cactgtggta gtaactgatg tcggtcaaca tcaaatgtgg gctgctaagt actggaattt
    17881 taaaggtaat aaaagtttta taacatcagc agggttagga actatgggat ttggtttagg
    17941 tgcagctatt ggaactaaag ttggtaatgt agataaaaat gtggttttag tcactggtga
    18001 tggaagtttt agaatgaact gtaatgaact agctacagtt gcaaattata atgtacctat
    18061 gcttatttta ctactcaata atagaacatt aggaatggta aggcaatggc aaaagttatt
    18121 ttccaatcaa agatactctc aaactgacat taatgaaaat gtggattatg ttaaactcgt
    18181 aaatgcatat aacattgatg gatataaggt atccagtatg gaagaattag gaaaggcgct
    18241 agatatgata gattttaata aaccagtatt tttgcaatgt gatatagata aggattatga
    18301 tgtttatcct attgtagcac ctaatgatgc attggaaaat ttgatatgta actaaaactt
    18361 atactgaata ttgataaaat tttttattaa atttttatta gtattcagtt tttgttgttt
    18421 agagatagat tggcattttt tatttttgca aataaatcaa tgactatata attaagaact
    18481 tattaaattt taattataca atttagaata gtattacaac ttaagtaaat aataattttg
    18541 aataataatt tacggaggta ttcatatgtt taaacacgat aaagcattat taaaagaagt
    18601 aaaagtagaa agaccaaatc ctcaatatgc tgttttaatg caagaacagt tgggtggtgc
    18661 aaatggagag ttaaaagcag ctatgcaata cttgtcccaa agttttagaa taaaagaccc
    18721 tcaaataaaa gatttatttc ttgatatagc agcagaagag cttagccata tggaaatggt
    18781 agcacaaact ataaatttat taaatggaca tgatgttgat tataatgcag ttaatacagg
    18841 cgaaatagaa acacatgtat taactggtct atcaccagtc ttaataaact catcaggagc
    18901 tccttggact gctaattacg ttacagttac aggggattta gtagctgact tactttcaaa
    18961 tatagcttct gaacaaagag ctaaggtagt ttatgagtac ttgtatagac aaatagatga
    19021 taaatatgta aaagaaacaa tagatttctt acttaataga gaagaagcac ataatgctct
    19081 atttagagat gctttaaata aagttaaaga tacaggttca aatagagatt ttggagttac
    19141 agaagattct aaattatatt tcgatttgtc tactccaggg ccaaatcacg atactaagat
    19201 agatattaat cctccttctt ttgaaaaacc tttaaaaaaa taatttgata ttttttattt
    19261 tgttttagta gttataaaaa ttatttacta gaagaattaa ttatatgaaa aattaaatat
    19321 gtatagttaa aaatgggtat acacttatta taagtgtata tctatttgtt tattgcaaaa
    19381 catataataa aataacaaat gaggtggtat tttggacagt aatagaaaac ctaataatct
    19441 aataaatgaa aaatctccat atcttttaca gcatgcttat aatcccataa actggtatag
    19501 ttggaatgat gaggctttta aaaaagcaaa agaagaggat aaaccaatat ttttaagtgt
    19561 aggatattca acatgtcatt ggtgccatgt tatggaaaaa gaatcttttg aagatgaaga
    19621 agttgctgaa ataatgaata gaaactttgt ggcaataaaa gtagataaag aggaaagacc
    19681 tgatgtagat agtgtgtata tgacagtttg ccaagctatg acaggtagtg gtggatggcc
    19741 aatgaccata ataatgacac cagataaaaa accttttttt gcgggaacat atttcccaaa
    19801 atattcaagg tataatagac ctggagttat agatttatta gagaatgtat ctgaaaagtg
    19861 gaatacaagc agagatatat taataaaatc tggagatgaa ataatagaag ctcttaagga
    19921 tgattttggt gtaaaaaata ctgagggtga tttatcaaaa gagatgttga gttcatcagt
    19981 tagagtattt aaggctattt atgatgaaaa gtatggtggt tttggtaatg ctcctaaatt
    20041 tccaagtcct cagaatctta tgtttttaat gaaatattat agtatagaaa aagacaaaga
    20101 tgtgttaaaa atggtggaaa aaactttaga tggaatgtat agaggaggct tgtttgatca
    20161 tattggattt gggttttcaa gatactctac tgataaaaag tggttggctc ctcattttga
    20221 aaaaatgcta tatgataatg ctatgcttac tatagctttt ttagatgcgt ataaaataac
    20281 aaagaaagag ttgtataaag aaattgctat aaaaactata gattatgtag ttagagagat
    20341 gaaggataaa gaaggtgggt tttattcagc acaggatgct gatagtgaag gtgaagaagg
    20401 taaattttat acatttaatc ctcttgagat aattgaagtt ttgggtgaag aagatggaac
    20461 tttctttaat aattattttg atataactag tagtggaaat tttgaaggca aaagtattcc
    20521 taatcttata aaaaataaag aatatgagag acataatgaa aagatagctg accttagtaa
    20581 aaaggtattt gaatatagaa aagaaagaac atctttgcat aaagatgaca agatacttac
    20641 atcatggaat gcattgatga tagttgcttt aacaaaggca tatagtactt taaaaaatga
    20701 catatattta gagtattcaa ataagtgtct taactttata aataataatc ttgtaaatga
    20761 gtcaggtaga ttattagcta gatatagaga tggaagttcc gactatttag catatttaga
    20821 tgattatgct tttttaatct gggcgtatat agagctttat gagtcaacat ttaatatgaa
    20881 atatttagaa aaggctttaa atttgaatga aagctgtatc aacctttttt gggattatga
    20941 aaaaagtgga ttttatatat atggtaaaga tagtgaaaat ttaatagcaa gaccaaaaga
    21001 tttgtatgat ggagctattc catcaggaaa ttctgttcaa ttatacaatc ttataagact
    21061 tgcgaaaatt actggagata atagacttga agaaatgtca tataaacaat taaaactgta
    21121 tgtggataat gtaaagagtt ctccaactgg ctacagcttt tatatgcttt cattgatgtt
    21181 tgaactttat tctactaagg aaattatatg tatttttaag gaagattctg atttaattgc
    21241 atttaaagaa ttgataagtg aaaattttat accaaatgca acttttttag caaagaaata
    21301 caatgaagaa aacactatta taggtttttt aaataactat atattgaagg atgataagac
    21361 tagttattac gtgtgtcaaa gtaatagttg tagtcaacca attaatgatt tacaaaaatt
    21421 aaaagatatg attttaggag tagaataatc ataatagcga aaaaggagat gctttaaaat
    21481 aaaagtctaa tcatctcctt tttttgtata aaaaacagaa aaagagttcc taagaacacc
    21541 taatctatgt aatgattgtt ttgttaaaaa ataaaaatga cattatagtt atataaaata
    21601 ttgtactata aaaaagtggt attatagatg cgatagtatt aatctttttt atttactcta
    21661 tttcttcttt ttgcaaattc ttcaagtgct tcagatttaa ttttatctat ttcttcatat
    21721 tccataaaat tagcatcttc ttcaaagcca tcttgttctt caccattaaa acgatacatt
    21781 ttttttagta aactccataa ggtctctaat tcatctttgg taaattcgtg aaatacatct
    21841 gccataaagt ttattccagt cctactacat gtcaccataa ccttttttcc taagtctgta
    21901 actttaacat taattgctct cttatcatga ggacttggaa ttacatcaac atatccattt
    21961 ttttcaagat tagcaactag tctatttata ttttgtttac ttgtacccat ttttcttgca
    22021 atattattta atgttgtttc ttcctctggt aaatgaagaa ttgataaaat agtcatatac
    22081 tgtcttgaag taagtatacc aaaatattta tctccttcta tttgtatttt gtttgtaagg
    22141 gtaaaaagag ttgcatatgt ttgattcatt aaaaagagct cttttagttc atttgaataa
    22201 tccatgaaat atatctcctt tatttttaga tgttgttttg tcgaaaacag aatatcatga
    22261 attaattcta atgtcaatat ggtgtcaaaa tatattaaag tattactttt ttatgtaact
    22321 attaattaat taaattattg tataatttta tgtaaaaact tctatgtacc aatgataact
    22381 tctatgagga attaataatt cttaaatttt ttagaaagat tttgacttga aaatacttgt
    22441 aatataatat ataaattaat atactgaata aaatcaatct ggagggataa ttatgaagtg
    22501 tacaaacttt actttcaaag gagaggaagg tttagatata tatacatata aatgggaaga
    22561 tgaaaatata aaaaaaccaa aggcagttat ccaaattgca catggaatgg ctgaaactgc
    22621 acaaaggtat gagacttttg ccaaggtact tactaaaaat ggttatatag tatatatcaa
    22681 tgaccataga ggtcatggaa aaactgcaaa gataatagaa aatgttggac atttagctga
    22741 aaaagaagga tttagatgtc ttgtagagga catgtatact ttaacaaata ttataaagaa
    22801 agaaaatgaa gatttgccaa tttatctatt tggacacagc atgggttcat ttgcaagtca
    22861 aagatatata atggattaca gtaataattt atctggtctt atactatgtg gttcaaatgg
    22921 aaagcaagga atcattctaa atcttgctca tctgataatc aatcgtgaga ttaaaaagta
    22981 tggaagacgt tctaaaagta ataaaataaa taatttgata tttggcggcg aaataataag
    23041 aagaaatgaa aagactaagt ttgactggtt aagtagagat aaagaacaag ttgaaaaata
    23101 tataaatgac ccattttgtg gagtagtgtg tagttgtggc tttttttatg atttagttca
    23161 agggttaaaa gaaattgagg ataaagaaaa cttaaaaaaa gtgccacttg atatacctat
    23221 ttacataata tctggagata aagaccccat aggaaaaaat ggtaaaggag tcttaagact
    23281 aagggataga tatataaaat taggagtaaa agatgtaact tgcaaacttt acaaagatgg
    23341 aaggcatgaa ttgttgaatg aaataaatag agaagaagtt tttgaggata taatttgttg
    23401 gttaaataat aaaatagaaa tattgtaata aaaaaatata atgatatatt tactttaaat
    23461 ttatttatat ataatatttg aaaagtggat tatgtatatg caaagtagaa aagagagagc
    23521 ccagaagtga ttttttgcta taatgccatt tattgaatag gtgggtgtta ttataaataa
    23581 attattaaca ctcagtatta ttatcattgt atatggaatt tattttattt aaaattcctt
    23641 gaaagtttaa atatagtaag ttgtagtaaa gagaaaatat aaatatttaa atgctattta
    23701 atgtgaatct attaattagg ttatacttaa acttaattaa tagattttat atttcaagac
    23761 aatgagatag ggttttagat taaaatataa ccaatggtta aattacagac attttgttaa
    23821 ctttccctcg atttactagt aaatattttt tttatatact taaattacaa cagatgtact
    23881 agggaggtat atatgcaaat taaaataggt aaagtcatac agtgtcttag aaaagaacga
    23941 aatttaactc aagaacaatt agcaaagttt ataggtgtgt caacaccagc agtatctaag
    24001 tgggagagtg gaaattctta cccagatata gaattattgc ctttattagc agactttttt
    24061 aatgtgtcta ttgataagct tttaaattac aagattgatt taagtgaaga agaagtaatg
    24121 aaaatttata aagaattaga atcaggcttt gctagaattg aaattgattt atcaacagaa
    24181 gaaccaaaag aagaatttag acaagactta gaatctgtaa aaaagctttc caatatgtat
    24241 atagagaagt atcctaaaag ctatttattg aagctaagga tatgttcgct gtatcagatg
    24301 tattcatata aatttggtaa gagtgaactt aatgacagag taaaagaaac aacgaatatt
    24361 cttgaagata tagtgagaaa tacagatgat atccaaataa aagaaacagc tcttattata
    24421 ttatcaaacg catattgtat gttggaggat tatgaaaagg cagagttgta tttaaatatg
    24481 atacataagt caatagggga tacaagtgtt aatttagcta tgatatattt aaatcaaaat
    24541 agacttgaag aagcagaaat attgcttcaa aataaattgt ttagtaatgt atttaatata
    24601 agcatggatt gtaagggaat aattaatgta tacaaaaatc aatacaagga attaaagaaa
    24661 aaattggaga atagaaattt taataaaaat gcaattgaga gagaaatgga gtatataaaa
    24721 aataagttgc tggggtatgc aaatctttct ttagaaataa aaaaaatgct cagtgaagat
    24781 aaaggtgcat tttttagtat gtatatggat tatatggaat tatctctaat ttttttattt
    24841 tttaacatga aagaggaagc aaaaaaagcc ttatatagtc taaaagaaat attagaaaaa
    24901 tatcctatac atgaaaattt ggatgtaagt caaatgagat tttttgataa ggtagagtct
    24961 aaaaatttat atacttttaa tatatataca aacttgttaa ttgtacttaa tgatgatagt
    25021 tataatgagc ttagagaaga accaattttt aaggatgtaa ttgaaaagat tttagatatg
    25081 gaaaaaatgt tgaaaaataa agaataagta aaaatttaat ataggactta aagattaatc
    25141 aaattaaaag aaagtgtttc aaaataaaaa tttgaatcac cttttttgtc ggtcttaaac
    25201 agttatttag aaaaatagag gtttcaaaat agaaatctga attatctgta ttattacaca
    25261 aaaatagaaa cctaaattta taaaaataga ataaagtttg ttatataaaa tgtaattttg
    25321 tctataaaat ctcacttgtt ttcttaactt taagcgtgaa aaagagaatg tatcatgaat
    25381 tttttagttc atgatgcatc cttctttgta tgaaatccaa tatatcttta ttatttaaac
    25441 aatggaaaag agccttattt ctattttgag acatctcttt tatttaatta tgaagtttta
    25501 tacagttcaa taaataggaa ttatatttag aaactcatga cattatttct tagatagtga
    25561 ttaaatttat catattccat tttagataac ttttctgggt aagacattac aatcaggtta
    25621 tgcccattaa atttttcatg gtatggtgga tgaatgtgtt cataattatt tgtcttatat
    25681 tttactcttt catagaacgc cttgcgataa attgaaatct catcaattgg aaggtcaatt
    25741 tctaaaataa tagtttttcc tttcttattt aaaagctcta acgctctttg cccatatcta
    25801 ttattgcgca tttctggaaa aatgcagaaa tgttctacat agataaagtc atctgtttcc
    25861 caacataaaa ttatgccgac aaactggttt ttatcataaa ttaaattgaa ttgatattct
    25921 ttatttttca aaatttctgc ttgcaaagaa gattttcttt gttcatgaaa tgggaaacta
    25981 attttatata attccatagc cttgtaatat aatttatttt cactggttct taaccgttca
    26041 aatttcactt tactcctcct aatcacgaaa attccaattt atttatgagt tcattttacc
    26101 atagtcagta tttgcataca atgtgtttta agttgagtgt catttctttc ttttatttat
    26161 gcttatatct catagtctaa gagataattg cttaagacat aactaaaaac tattatatta
    26221 agctttgata atctaaaaac agtatattta tggacttttc taggtctaaa agtaatctta
    26281 ataattttag aagttacaaa aaagttacat aaatttggaa agctataata tacatatata
    26341 atataaggtt aaaactgtaa tgaataatat taatttaaaa tttgaacatg gaaggagatt
    26401 attatggaga aaagagaaaa gaggataata atatcatctt tattaagtgt atcaatttta
    26461 atgggtttgg caagtatata ttctatatta aataaagaag acataagttt aaccgttaaa
    26521 ggtcaagagc aaaaagtatc ttcctttaag aaaacagttg aggaactttt ggatgaacag
    26581 ggtgtaaagt ataattctga agataagatt aatccaagtt tagatacaga actaaaagat
    26641 gatatgaaaa taaaagttgt taaggtaact aaaagtaaaa aagaagagat tgaaaaaatt
    26701 ccatttgata caaagcatgt aaatgatagt aatttgttaa aaggaaaatc taaagtttat
    26761 caagaaggtc aagaaggaga aaaaaaacta gtctataatt taacttacca tgatggaaag
    26821 ttagtcaaaa aagtcttatc aaaagaagta atatctaagg agccaactac aaaaattata
    26881 aaatatggaa ctaaagaaaa agtattaata gcatcaagag gagcaaatat aagaggaggc
    26941 aaacatatga aagtggttgc cactgcatat gcaggagata caataacatc tactggtaca
    27001 actccaagat ggggtgttat tgcagttgac ccacgtgtaa taccatatgg aacaaaagta
    27061 tatataccta aactgggtat gacttttgta gcagaagatt gtggaggtgc aattaaaggt
    27121 aatagaatag acatttttat gaacagtgaa ggaaaagctt caaattgggg aaggaaaagt
    27181 atagatatat atctacatta aattagtgaa tagaataact ttacttgaag gacaaaaaag
    27241 tataaaatat gaattaacta aactgttaga ttattcttaa aacataaaaa tatatctaag
    27301 gggggataag atgaaaatag tctgcttagg agacagttta acgtatggat ttggagtatc
    27361 acgaagtaat tcatggacaa acattgtaaa taaagagact cgattagaaa tattaaataa
    27421 gggtataaat ggtgatacaa caagtggtat gttagctagg tttaatgaag atgttgtaaa
    27481 aaactctcct gatatagttt ttataatggg tggtaccaat gattttattg ctggtgcggg
    27541 aaatgaaatt attaattcta atataatggc tatggtgcat cagtcatatt caaaaaatat
    27601 tatacctata ataggtatac cattaaaacc agatattcca aatgttaggg aagattggag
    27661 ttgttttact gattttaata tagtatctca aaacttagaa tcatatagtt attggataaa
    27721 aaaattttgt atgacattta atactaattt cgtagatttt tattcagaat ataataaaaa
    27781 tatggaacta gaaggatata aaaaattata ttttgatggg ttacatccaa ccaaagaggg
    27841 tcatagaata atggcagaca tttttattaa ttcaattaat aagtatatag aagagttata
    27901 gattacatta aaatgcttgt ttatgcatca gttgcaataa atacatacag tagagagggg
    27961 tttattatgg attatactaa aacttatgaa gagtggataa agggttcata ttttgatgaa
    28021 gatacaaagc tagagttgga gaatataaaa aataatgaaa aagaaataga ggatagattc
    28081 tataaggatt tagaatttgg gactgcgggt cttagaggaa taattgaagc aggaacgaat
    28141 agaataaata agtacacagt tagaagagct acttttggat tggcaaacta tatattagaa
    28201 aacacaacaa aagaagaaac aagtagagga gtagtaatag ctcatgataa tagacacaag
    28261 tctagacaat tctgtataga atctgcaaat actttggcag catgtggtat aaaagcatat
    28321 atatttgata gtttgagaac tactccagaa ttatcttttg ctgttagaag cttaaatgca
    28381 atcgctggta tagtcataac agcaagccat aatcctccag aatataatgg atataaggta
    28441 tactgggaag atggagcaca agttatgcca gagattgcaa atgcaataac agagaaagta
    28501 aatagtatac atgattatag tacaatacca accttaacgg aagctaataa aaatttggta
    28561 gttttgttgg acgaatcaca agatactaaa tttatagaag cagtaaaaag ccaaattata
    28621 agaaaagatt tagttaaaaa tgtaggtaaa agctttaaga tagtttatac acctctttgt
    28681 ggaacaggga atgttccaat aagaagagca ttgaaagaag ttggttttga aaatataatt
    28741 gtagttccag aagaagaaaa tccagaccca aattttgcag ggcttgatta tccaaatcca
    28801 gaagagaaaa aagctttaaa tagaggtata ttactcgcaa aagaaaaagg agcagacctt
    28861 gtaatagcaa ctgacccaga ttgtgataga gtaggtgtag cagtaaaaac tactacaggt
    28921 gagtatgctt tacttacagg aaatcaaatt ggtggtatgc tgacacatta tataatagaa
    28981 ggattaaaag aaaataataa attaaaagaa aatcctacaa taataaaaac catagttaca
    29041 tcagaatttg gagcagatat agctaaagca aataatgttg atgtattaaa tgttcttaca
    29101 ggttttaaat ttattggtga aaaaataaaa ttatttgaac aaaataaaaa tagaagttat
    29161 gtatttggat atgaagaaag ttatggttac ttagttggga ctcatgctag agataaagat
    29221 ggtgtagttt cttcattgtt aatatctgaa atggcagcat tttactattc aaaaggtatg
    29281 agtttatatg atggtttaat agaactttat aaaaagtatg gatttttcaa agaacagact
    29341 atatctttga ctttaaaagg tatagaaggt gtagaaaaga taaaagaaat aatatcttat
    29401 tttagagaaa atcaaattga ttatataaat agtattaaag tagttgataa aaaagattat
    29461 aaaaatggta tagataatct tcctaaatct gatgttttaa aatacttttt ggaagatgaa
    29521 tcttgggtag ctataagacc atctggaaca gaaccaaaac ttaaatttta catagctgta
    29581 aaaggagcta gtgatattga agcagataaa aagattcaag gtttgaaaaa gtatatagat
    29641 gacatggtcg aaaaattaaa ataaaatatt attattttat aagataattt tgtaataata
    29701 tttatttagc tgaaaattat aatttacttt cattgagtag aatatggaaa tgttagtaga
    29761 attgttattt tcagctttta tttgtgttat ttttacttaa ataattatat tatagaatga
    29821 atctgagtat aattaatatt gtataatgaa attaatttga tagaaaaggg gatatttatg
    29881 tttggtatag ataagaaatt gattgaatat ataattgcaa aatccaatta cagtgaatta
    29941 agttcaaagt cagcagaagt atctttcttc ttaatgttgt ccatatttcc ttttttaata
    30001 tttacaataa gttctatagc ttatataccg attcttcatt taaataagta tatagctttg
    30061 tttagaaata tgatgccaga aggtgctttt gctgtgttat cttcaatcat agtttctgca
    30121 atagacaata gaaacctgaa atttttagca gtcagttttg tacttactat gtggacattt
    30181 tcaagagcag taaaagctct tattaaagga atgaatagag cctataaagt taaagaaact
    30241 aggtcttttt ttaaaatttt atctatatca tttttattta caataatgct tttggtcctt
    30301 atttttttat ctatgatatt tttagtttat ggggaaaaaa taggttattt tatttttaat
    30361 cttgtaggat tggatgagat atttataaaa atatgggata ttctaagata cactgtaggt
    30421 ataataacaa taatagtgat atttacactt ttatataaat acactccaaa taaaaagcta
    30481 actattaaag aatctgcgcc aggtgctatt tttgctactt ttgcttggtt tttagtatca
    30541 tttttatatt cttattatac aaattactat gctaactatg aagtaatcta tggaagtata
    30601 gctgaaataa ttgtacttat gacctggatg tattttagta gttggtctat cgttattggc
    30661 tatgaggtaa attcaagatt gtattttaga aagataagac atgaaatgtt aaagtaaagt
    30721 atttaaaata aaagagagta tttagtatta taaatgtaat tgaattaata aagaaatatt
    30781 gacatttaag ttaaaaagtc tagaattttt ctgggctttt tttattttta gtataacttg
    30841 acaaatttta tttaatggga tagttttaat ttataatcat ctttaaaaag atgactattg
    30901 ataagtaaga gataaaattg gtaagtatca aaaaatatac taaataaaaa ttatagtcct
    30961 aatgagttaa tttctgtatt ttcaaataat gcagtattta gtcatgtgtt tttatatgcg
    31021 cctgtatttc taattaccaa tatattagaa taagctactg taattagatt tagaaaaaag
    31081 cgacataaat aattataaac aaataataaa ttacataaaa ttaaatttat tcacaagtat
    31141 atcttataaa atatgttata attaatagaa aattgtcata taattaatta agtagtatta
    31201 ttataaataa cattgaaagg tagtggttag aatatggata cccataataa atatgtaaat
    31261 tttataaaaa atatacctgt acctttttta tattgtagaa ttgtaaagag acaagaagat
    31321 atagaatatc gagtagaata tataagtaag ggtatgggca aagtattaca attagaagaa
    31381 ggtatttgtg ataaaaatat actagatgta ttgcctgtat ttaagtctaa aaaatatttc
    31441 aaagagttgt tctcaaatga agtggattgt ataaaaaggt acattccgac acttaaaaac
    31501 tggataaata taaaaaaaca gataataggg gattcataca taattttgta ttttggtaaa
    31561 attgtatttg attatagaca gataatcgat tcctttgata aaaaggaaaa agtagcttat
    31621 attaaagacg aagaaggcat atatatagat tgcagtgaaa atttaatacc aatattaaat
    31681 aacaacatta aaacaacgaa agatatcttt ggtaaaaatg atatagaagt atggggagag
    31741 aatacaggaa aattatttag agatgattat agagaaggag tatctagtaa aaaaagattt
    31801 ttacaaaatc tttttgaata tgaagaaaca ttttttatgg ttgaaaaata ttttttgtat
    31861 gatgaagacg aacttttagg tactataggg atagtagaca atataatata tagtggttac
    31921 agtaatagaa attataactc aaaagattta atgaagatga tagaacactc aattccagag
    31981 aatatgtttt ataaagatgt gtatggaaat tatattggat ttaattcagg ttttttgaat
    32041 ttagcttgta tgaataaaga agaattatta gggaagaata gttataaaat atcagaagaa
    32101 gaagctttaa tagataagat atttgaaagt gataagggtg tagttgaaaa taaaaaagta
    32161 gttacatttg agttaaatat aagtatgaat gatgaaaaca agtgcattga gattacaaaa
    32221 aggccgtttt ttgatagcta tggaagtgtt attggaataa ttggaacagc aagggatata
    32281 agtagaagaa aaagattaga agaggaaatg gataaaacta ggatggaatt ttttgcaaat
    32341 ttatcccatg aacttagaac gcctataaac ttaatatcat cttcattaca agtgatagaa
    32401 aaaaaagaag cagatttaat agaatcaaat gatactttaa aaagaaattt aggtataata
    32461 aaacaaaatg gaaatagaat actgaggtta gtaaataatg ttatagattt tacaaaaatg
    32521 caatcaggat atttagattt taaaccagaa gaatctgata taattgcatt tatagaggag
    32581 atatgtatgt ctgtagctga ttttgcaagc caaaataata tacaacttac atttgataca
    32641 gaaatagaag aattttcaat gttatttgat tcagaaaaat tggaaagaat aatattaaat
    32701 ttactttcta atggaattaa gtacaataag aaagatggaa aaataaatat atttttatat
    32761 gtgaaagata atgtatttaa tatgaaaata tctgatagtg gaataggaat accaaaagaa
    32821 aaaatagata aaatatttaa taggtttgaa cagattgaca atgaactttc ttacagagtt
    32881 aaaggaagtg gtattggact ttcattagtg aaatctttgg ttgagttgca tgagggaagt
    32941 atatctttaa aaagtcaact tggtattgga agtgaattta tagtttcatt gcctgttaga
    33001 agtaaaaata atattgaaaa atataatcat aaaagagaaa tcagcaatga actaagtaaa
    33061 aaattagaaa tagagttttc ggatttataa gtttaaatat aaaaaataaa attttaaaaa
    33121 agtattgaca attgatttag aagggtttaa aataaattac aacataataa ataaaaaggc
    33181 gatgaatagg aagagtaaat ctaattcgat taccagagag aagagtccgt tggctggaag
    33241 actttttaaa ttagagggat tgaaaactac ctaggagcta ctttctgaag tcatctgcat
    33301 tagtagattt tagtaagaat agtcgttagc tgcgttaaag tgtaaagtga gttttcatga
    33361 catatgaaaa ctaaattagg tggaaccgcg ggaataatac tctcgtcctt atgttataag
    33421 gatgagagtt ttttgttatt taaaaatata aacagtaatc ataataatta tagaaaatat
    33481 aaaagcaatg aataggaaga gtaaatttaa ttcgactatc agagaggaaa gttcacaggc
    33541 tgaaagactt tctaagtttg agaaattgaa aactacctag gagctgtggt ctgaagttac
    33601 tttaaaaagt tttagtaaga ctaaccgtta actgcgttaa agtgtaaagt ggattttatc
    33661 aataaatgat aaaatcaaat tgggtggaac cgcgagtata gactcgtccc tttatatagg
    33721 gatgagtcta tttttattgc aataaaagat tgaaaataaa aaaaaatcgg aaaattataa
    33781 atttaggagg aaaataaaat ggagaataaa gtgaaaattg gagtactagg atatggagtt
    33841 gtaggaagtg gacttataga tataatagat aataataaag aaaaaagaaa tatagaaata
    33901 gttggaattt tagttaataa tttggaaaaa cataaggaca aaaaatattc taatataata
    33961 actaataata tagatgatat atttaataaa gatatagata tacttgttga agtcatgggt
    34021 ggtttagaac catcattatc ttatataaaa aaagcattaa acaataaaat tcatgttgtt
    34081 acagcaaata aagatttgtt agctgaatgt ggagatgagc ttgcaaaatt agcaagtgaa
    34141 aataaagtaa gtattaaatt tgaagcttca gttgcaggag gtataccagt attaaaacca
    34201 ataatagaat cactagaagg aaataatata gatagtataa atgcaatttt aaatggaact
    34261 actaatttta tattatctaa aatgtatgat gagaatctat cttatgatat ggcattaaga
    34321 caagcacaag aattaggttt tgctgaagca aatccagagt cagatgtatt agggtatgat
    34381 gctgctagaa aactatcaat attatcaact ctagcttatg acaatagagt atattggaaa
    34441 gatgtgtatt tagaaggaat tacagatata gatgaaaaag atattgaata tgcaaaaaaa
    34501 ttaaattgta aaataaaatt gattggtcaa agtaagtatg aaaatgataa agtaagtgct
    34561 tttgttagac ctgttttagt agaaaaagat aatatccttg ctagaataga caatgagttc
    34621 aatgctgtca tagtgaatgg agattcagta ggagaagttt cttttgtagg taaaggagct
    34681 ggaagtttag caacaggaag tgcggtttat tcagatgtta tagatataat agataataga
    34741 gtttcaagta tagattcttt tactaaagat aaaatacaag ttaataaaat agttagagaa
    34801 aagtgtggag cacttcttag atttaaaaaa tgtaataaag atgaaattct aaatatagtt
    34861 gagaattgtt tagtaaaatt cgatatttta aatgatgatg atgaacttgc tattatggtt
    34921 tatgctgatt ctgaatatga aataaacaac agtttatgtc taataaaaga taaaggatac
    34981 tgcgaaaaaa tgaataaaat gttgaaaata agttaaaaaa gaaaaaatat aagtttatat
    35041 gtaacatatt ttgacgattt taatactata tagtatgaga tgaaacaaaa catctcataa
    35101 aaaaattaaa attaaaggga gagatatgtt atatggaaaa taaaaaatgt tattcagaag
    35161 attggtatga aagaggagaa tctacagcta aatggttcca aaatgataga gaagaatatg
    35221 aaagagaagc atatgatgaa gatagagaaa gaagaggttc aaactgtgga tgttcagatt
    35281 caggagaaaa tagacctaga aactgtgaaa gatttagaag agaagctgag ataagagaaa
    35341 gagaagcaag agaagcattc tgtgaatctt cagagaaaaa gaaagaggca ttagcatatg
    35401 aatgtgaagc tagaaaatta tgggaagaag cagaaaaata ctgggatgaa tattcaaaat
    35461 acaactataa aggaatcgaa tatttagcag aagctgctag attatttgat gaaggtatgg
    35521 aatgtgaagc tagaagaaat ggaaataatg gaggaaacaa taataattgt tgccataaat
    35581 gccataaatg taattgtaac tgctgtagaa aataaaaaaa ttaattgaca aatcaatagt
    35641 taaaatatat catattatgt ataataaaaa gaaaattcag aaaaaaataa tgattagaag
    35701 aaatataagt atatttatta gacaaatagt gctcagttag tgaggtgagt acaatatgat
    35761 taaactccca tcctctagct tttgatagag ggtgggagtt tttatttatt gatatatctt
    35821 aaatgaggat aatattgtaa aataaatgag tatgagattg taaaattagg aggtaaaaaa
    35881 tgaaaagtat taaaacatca agtatgaaag aaaaggtaga tgaaaagata ttaagagagc
    35941 aagtaagttc tataatagaa gatataagaa ataataagga tgttgcactt aaaaaatata
    36001 atgagaagtt tgatagaaat acaagagatg aattcagaat tactaaggaa gaaataaagg
    36061 aagcttataa gcatgtagat gacgaattta taaataactt aaagattgct gccaaaaata
    36121 taagagaatt tgctaaagct caaaaactaa gttttgaaaa cccttttgaa aaagaaattt
    36181 atccaggtgt aatcttaggt caaactaata ttccaataga gtcatgtctt gcatatgttc
    36241 caggaggtca gtatccattg ttttcaacag ctcttatgct tataatacct gcaaaagtag
    36301 caggagtaaa aagaatagtg gcatgttcac caactatgaa aaatactgaa aagataaatc
    36361 ctaagacatt ggtagctatg gatatagcag gtgctgatga aatatatgca actggaggag
    36421 ttcaagctat agcagcattt acatatggaa cagaaaagat taatccagtt gacataattg
    36481 taggaccagg aaataagttt gtaactgaag ctaaaagaca atgttatgga caagtaggga
    36541 ttgattttgt cgctgggcca agtgaagttc ttataatagc ggatgaaact tcaaatccag
    36601 tttatattgc agctgattta ttagcacaat gtgagcatga tttaaatgca agaggaatat
    36661 tattgacaaa tagcttggaa gtagcacaaa aagttgaaaa aaatatagaa agtatgctaa
    36721 aagatttgcc aacaaaggac atagcatata gttcatggga aaataatgga gagataatat
    36781 tggttgatga tatggaagaa gccattaaaa taagtaattt ttatgcacca gaacatttag
    36841 aagttgcagt aaatgagtat aatgatattt gtgatagatt aactaactat ggttctttat
    36901 ttattggaaa tctttctgct gaggtgtttg gtgactatgt ttcaggtacc aatcatacat
    36961 taccaacact taaagcatca agatatactg gtggtgtttg ggttggaact tttatcaaaa
    37021 cttgtacaaa gcagatattt aatgaaaaag ctatacaatc attagcacct gtagctgaaa
    37081 agctggcaaa agaagaggga ttatatgcac atgcaaaggc tgctgaggtt aggtttaaaa
    37141 agtagtaaaa aattttattt tggcagtcga gacttagtat tagactgaga taaggaaaac
    37201 gctgagaacc tgaataaata ctatattttg tgggtctcgg cgcttctttt atatctgtat
    37261 ataatagaat aatactatct gtgtgtttaa atactaactt aatatttctt ttctaaataa
    37321 tgtttatgaa atagttaata tttttagtta atacttgaaa aaaacttttg ctaactgtgc
    37381 aaattcatct gcatttgtca atatagcagg gtgtcctccc tgactaaaaa tgtaaatact
    37441 tgcttttgaa ataaaagttg ccatttgctt gtactcttct tcaagattat gacgacacat
    37501 ttcgtcttcc ttacttcctg taaataaaat tggcatttct aatttacaca attctttatg
    37561 aaacaaaggg cgtttctcgt ttgcacattg caatagagct tttgtatcaa gattaacaac
    37621 attctcccaa tcttttccat gacaccattc atagaatttt cgtgcttgaa tatcttgctt
    37681 tgatttttcc cttccagtga ttagattatc tatgaagtta tcattaagag tacgtccatc
    37741 aaagctatct gctataattg cttcaactaa atcgggacgt tctaatccag tattaacagc
    37801 tgcccatgct cctccacttg ttccaattaa gccaacttta ccacaattca aatgttcaat
    37861 cagtgctatt gtctgtaagg cttcatcatg ccatatgtca ggagaaaatt gagaaactct
    37921 atccgactgt ccattaccta aaaaatcaat taagatacat ctaaaatttt ctgcatataa
    37981 tggcacaagt gctttaaaca tattagaaga accagtatta ccatgcagga aaattatcgg
    38041 tttaccttgt ccatattctt tataaaaaca agaattacct tgatactgaa aatatgacat
    38101 atattttcct cctttttatt tgttaagtta attataacaa tataggtatg aatgaaaaac
    38161 ctcatgttct ttcttagaat aaaaatgtgc cacgcataaa acgtgacaca tttctaatta
    38221 taaattttgc tgtttaagta ttctttgtat gcttttctct gtcaaaaagt atttctctga
    38281 taactgcttg atactcattc cattttggaa atttatacag atttgagaat tacgagaagc
    38341 taagacttgt ttggtgtttg tgttttcacc ccaatgcttt ttgtgctctt gctttttggg
    38401 aatataaatc actttaccat ctatatattc ttgcacttgc tcaatcagtt ctttaggcag
    38461 taagtcaatc gaattttgat agctcatttt gcacctccta aataattatt ctttaggatt
    38521 agcaaaggct actgccactc acaattaaaa ataaaatttt ttattatgta caatagcctt
    38581 tgctatgcac aagttccaat tcccataaac taaatactcc tttctggttt gaaaaattca
    38641 tctgaacatt gatttcgctt ttaagataga gttcaatgac aaatttacat ttttattata
    38701 tatattcaga tagataattg caactgtctt tgtatgagga tattttatta tagtcaatac
    38761 tataatatgt atttatatca tcaaactaat atgaacagtt gaaaggaata tgaacaataa
    38821 aacttagtca ggaagaataa ttatgaagca gacaatagag aaatttgatt ttaaagtttt
    38881 attgaaaatt tattgacaaa tttaacttgt aaatattata ctaaacttaa taaataaagt
    38941 ttataaagta aggtgttgtc tatgaaaaat atagttggaa aaccgcaaac gataaaaaaa
    39001 gtaaatgaag atttaataaa aaacattata aaaaatgaag gtcctataac aaaaccagaa
    39061 atttcaagca ttactgaatt gagtttagct acagttaata agattgtaga gcaattagct
    39121 ttgaaaaatg aagttaaagt aagtggacta agtgaatcta ctggaggaag aagagctcaa
    39181 ttatttgaaa taaatgcaaa cttagaacac ataatagctt tatattatta tagaaattgt
    39241 tgtatagggg tagttgccaa tttattaggt gaaataattt atcaagaaga atttaatata
    39301 agaatggata cgtatgaaaa cgttaaccaa gatacttttt ttgttataga tactctaata
    39361 aaaaaggaaa aaggaaacaa tataagggct attggaattg gtgtcccagg agttgtaaaa
    39421 aaaggtgtag ttaaaaatat accaactata aaaagttggg aaggtataaa tttagaaaat
    39481 ttaataaaga gtaaatacaa tactaaagtg tttatagaaa atgatacaaa tattactact
    39541 attgggattt atcaaaaaca gtataaagac aaatataaaa atatggctct tatgtattta
    39601 gaagatggta ttggttcagg tatagttata aatggtgaat tgtatttagg ttctacaaat
    39661 tttgctggag aattaagtta tctaaatata gaatttggta agtataactc taacaactta
    39721 aatcttgaag attatattat gagtttaaga aaaagatatt tagaaagtaa agataataaa
    39781 tttaagaaag aaattttatc tataatatca aactttataa ggactcttgt atgtgtccta
    39841 aatccacaag ctatgattat acagtgtagt atattaacca agagtgacat ggagtttata
    39901 gaaaaagatg taagcaataa tgttggagaa gaaaattttc ctaaattaat aaaagtagac
    39961 tcattgagag aaggaagtat aaatggagta attagtatgt gtttaaaaga aactgactat
    40021 caatattcct tatctaataa aaaaggagga tattaatgtg aaatatttgg tttcaataga
    40081 tggaggggga acaaaaacta aattttgtgt aagtgactta gatggaaaca tacttaaaga
    40141 acataccact ggttcaacta attataagtc agttggaatt aaaaaaacat atgaaaatat
    40201 taataatgga tttaaaaaaa tattaaaaga tttatatatc gattatgacg atattgagta
    40261 cactgtattt ggtatatctg gttgtgattc tcctaatgat tataagatta taatggatga
    40321 aatattaaaa attgggatta acaaagaaaa aatatatctg gcaaatgatg cagttttagc
    40381 tttttatgca caagctgatt cccctggttt agtaattgtg gctgggacag gttcaattat
    40441 actgggaatt aaagaagatg gagaaatata tagagttggt ggatgggggt ataattttag
    40501 tgatttgggt tctggatatg atatagggag aaaattatta aagaaagtat tgctttattg
    40561 tgatgaatgt catgagtata gtgatttatt tagttgtgtc ttggacttct ttggagcaaa
    40621 tagttttgaa caacttgcat atatgattac tgatataaat gataatgttg aaatagcaaa
    40681 cttagcttca ttagtgattg attgtgccga acgaggtgat aaattggcta ttgaaatatt
    40741 aagagaatca tcaactgaac tatctaaatt agctcaagta atattgagaa aaatatctaa
    40801 tccaatgaaa atggataaaa gcgaaataaa tatagttttg tctggtggta cattaaataa
    40861 aactgtatat gctcaaatgt taatgaataa tttaaaaaca gaaaatacag ataaaaattt
    40921 aaaatttata tctcaagaaa atcagccagt atatgggggg ataagacttg ctatggcatt
    40981 agctaatagg agggtcaatc atggatagaa aaaaggtaat agtacaaatt tttactggag
    41041 gttttaaggc taaagaaata aagtttaatg atataaaatg taaactacta gaattattgg
    41101 actgtattga tatagaaaag gttatcatgg gatggagtgt agatgaagaa ttatatgtag
    41161 aaactaaaaa actattaaat aaatataatg ttgaactata tctttggttg ccatgttttt
    41221 ctgaaatagg attacttgaa aaaagtaatt tactaattga ttatatgggg aaggaagtca
    41281 agggctatgc tttacaagag gatgaaaatt ttgagtttta ttgcccaaat aataaggaaa
    41341 atataaaaaa tataaagaaa atatatagta cttattttag tgatattaaa tttgatggaa
    41401 tttttttaga taaaataagg tatggttctt tttcgaataa actaaatggt gtttttaatt
    41461 gtttttgtaa agattgttta aatatatatg aaaaaaataa tattgataaa gagtcgttaa
    41521 tgagagaaat gaataatgtg tctaagggag ttatagataa tgaagatact ccatttggta
    41581 taacagaata cattaatgga aaatacaaat ttaaaaataa aatatgggaa gatttttttg
    41641 aaacaaaaaa tcaaaatata tacaaggcat tattagagat aagtagttat tttaaaagta
    41701 agggattgaa aataggtata gatacttttt ctccttttat ttcttacttc acaggtcaag
    41761 atttagaaaa attacaagaa gtagcagatt ttataaaacc aatgatgtat agaactacaa
    41821 aagctccagc tggtttacca tttgaatttg aaaggtttat tgatgaatcc atacataaga
    41881 ataaagagat tggaaaaaga aatttcttag atattttagg aattaaggag tatgaaggag
    41941 atgtataccc tatagaattt gtactagagg aaatcgattt tatgacaaga aatcttaata
    42001 aagatgtata tgtaggagtt gaaataaata aaaaggaaat tatatctcct gttacaccta
    42061 agtacataag tgaaaatatt tcaaatataa ataagacaac agtaaaagga tatgttttat
    42121 cttgggattt gttgtcagca ccaaaagaaa atattgatga aattataaaa tggtttcgga
    42181 attagtgagg tgataaagtg agtaagatat tggaaatgca acaaatatat aaaagttttg
    42241 gaaaggtaga tgttttaaaa gggataaatt ttgagttaga aaagggagaa gtaagagctc
    42301 ttttgggagc taatggagca ggaaaatcta cacttattaa aattttagga ggagttcatt
    42361 ctcaaactaa aggtaaagta attttgactg gtaatgaaat aatgtttaaa aatccacatc
    42421 attctaaaga aaatggtatt agtataattt atcaagaatt aagcttgata ccaacgctta
    42481 cagtacttga aaatattttt cttggtagag aaattttaaa aggaagtgtg tttttaaaca
    42541 agaaagacat gcttgaggaa tatatgaaaa tttgtgagga ttttgatttt aatatagacc
    42601 cacatatagt agtttctaat ttaagtgtag caaaccaaca aatggttgag ataatgaaag
    42661 ctgtttcatg taattctgaa attatcataa tggatgaacc tacaacatca cttactaata
    42721 atgaaaaaga tgggctattt aaaataataa gtagactaaa gtctaaaggt aaaacaatag
    42781 tctatatttc tcacatatta gaggaagttt ttaaagtatg tgatagtgca agtataatga
    42841 aaaatggaat tatgattgga acttatgatg tagaggattt aactaaatta aagataactc
    42901 aacttatgac aggaaatgat aatcacaaac ttattgagaa gaaggattat acatttgcaa
    42961 aatatgaaga gccaccagta ctagaagtaa agaatataag ctggtctaac aaaataaaaa
    43021 atgtttcatt taaagtttat agaggcgaag ttgtaggtct tgcaggtctt gtaggttcaa
    43081 gaagaactga aattataaat ttgatatttg gtatagataa taaagatagt ggagatattt
    43141 ttatcaatgg taaaaaagta gacataactt ctcctaaggt tgctataaaa aacaaaatag
    43201 gattgattcc tgaagataga aaaaatctag gattaatttt agaacaagct atatacacaa
    43261 actcatcatc agtacaaatt gataaattca agaaattctt gtttatagat agaaataaag
    43321 aaattgagtt ttctaaaaaa ggtgttaagg aattaggaat aaaagttagt gatgtaaagc
    43381 aagaagtaaa agagcttagt ggtggaaatc aacaaaaagt agtagtttct aagtggttag
    43441 agaaagattt agatttaata atatatgatg agccgacaaa gggaatagat attgctgcaa
    43501 aagaagatat tttcaataca atcaaagaat tttcaagtaa aggaatagga gtaatattta
    43561 tatcttctga tttagaagaa gtaataagag taagtgatag aattttagta actagagaag
    43621 gttctattgt agatgattta aaaaatgaga atatacaggt tcaagatata atgaacagta
    43681 tatttaatgt ataaaaaatg aaaatggagg actgaaatga agaaagcttt tgagaagtta
    43741 aatttaagag attatggagt attattaggt tttttagctt tatgtatagc tataagtatt
    43801 gcaactccat catttttagg taaacaaaat atacttaatc ttttacgaca atcttctata
    43861 attggaataa tttcagcagg tatgactttt gttataatat ctggaaactt tgatatatca
    43921 gttggagcag tagcagctct tgcaggtgct ataacaatga aatttgcgac tggtggaact
    43981 aatttgtttg catccatgct cttaggtgta gcgatttgtg cagtaatagg attaatcaat
    44041 ggtatagtag ttgcaaagat aaatgtacca tcattaatag ccactatggc tatggtcact
    44101 attgtaagag gattgctgtt gatgcttaca ggaggatatc caattactga aaatatacca
    44161 atacttgatt acattggaaa tggatatttg tttagtatac caataccagt agtaattttc
    44221 tttatagtgg tgttagcttc gtttattgta cttaataaaa ctaagtttgg tagatatgtt
    44281 tattctgtag gagggaatca agaagcaagt aaacttaatg gtataaatgt agattctcac
    44341 aaagtgaaag tgtttattat taatgctgta cttgcaggaa tagctggaat cgtactaaca
    44401 ggaagacttg ggactgcaac tgcgattgca ggtgaaggat atgatatgga tgcaattgca
    44461 tctgtagtaa taggaggtac atcagtggca ggaggttctg gttctgtact taaaactgtt
    44521 ataggagtat tacttatgag tgttataaac aacagtttta atcttcttgg aatagatgta
    44581 tatttccagt acatatttaa aggattaata attttagcag cagttggatt tgattcttat
    44641 agcaagaaaa aacttgcttc aagataaaaa ataaggggga tttttttatg aaaaaattaa
    44701 tgaaacattt agcattgttg ttatcacttg ttatgatatt tggtttagtt ggttgttcaa
    44761 atggtggtga caaagaaaaa aatggagaaa agaaaatagc agtattacta ccaggttcaa
    44821 caggttactt tgtagcaact aaacaaggta tagatgcaaa atctaaagaa ttaggtgtaa
    44881 gcgttgaata tgcagatgct caatgggatg ctagtaaaca attatcacaa gctgaagatt
    44941 ttatggctaa aggggtagac atgattgcat tatgtggagt tgattctgct gtaagtgaga
    45001 gaatagttaa agctgctaat gattcagacg ttcctatagt agcatttaca aattctatag
    45061 gaagtaaccc aactggagaa tttaaaggtt tagttacata tatagggcaa aatgaggaag
    45121 aaacaggagc attaactgga aaaattgcta aaaacttatt aggagaaact ggtgggaaag
    45181 ctgtattaat agaaggagta ccaggaacta ctccacaagt attaagaaaa aaaggtcttg
    45241 aaaaagaatt aaaagatagt aatatagaaa tagtttataa tcaaacttca aattgggaga
    45301 aagagcaagc tttaaaggta acagaagatt taattcaaaa gaaaactgat tttaatgtta
    45361 taatatgtca agatgataat tctgctacag gtgcaggtca agctttaaaa gatgctggtc
    45421 ttaaggataa agttaaagtc ataggtttgg gtggaagtaa agatggatta aaagctataa
    45481 ctgatgggtt aatagatggt acaacttata tgtctgctgt agaagaaggt ggattagtca
    45541 tagaaaaggc atctaaattc cttaaaggtg aaaaaataga acctgttaca caaattaaac
    45601 aagttgaagt taacaaagat aatatttcag agttcaaggg tgaatggtaa attgtcatag
    45661 ataataaata agatttttag agttacttta gaaactatat aaagtaactc tttttttaat
    45721 ttaatttagt gataaattat tgaatagtat ttctaaacaa ataaaaaatt aatataaaca
    45781 aagacttaat tatactaaat tataagtaaa actaatataa acttatggaa aaaaggaaaa
    45841 cgtctaaagc attggaatta ctatagtgta ggtgtggtat taaaaaaaca taaaaaaaca
    45901 taaaaaaatt gttgaaaaaa atatagaaat tttgtataat taaagatttg aaaagtgcgg
    45961 tatacaaagc caattctttt gtatataata tatataaatt cagaaaaagg aagggatatg
    46021 tatggccagg cggttatttt tagaaaggat tggacttata tttttaggtt cagcaatatt
    46081 agcatttgga gtttataatt tttattattt aaacaacata acagaaggtg gagtgttagg
    46141 tattttacta ctgttaaaaa atttattcaa tatacaacca gcaatagcaa atgttgtaat
    46201 agatggttta ctacttttag taggatataa atttttcggt aaaaaattcc ttatatattc
    46261 aatagtagct tctataactt tttcagtgtt atatgactta tttgaagcta taggacctct
    46321 agtaccacaa tcacaaaata tgcttttatc aactattttg gcaggtgtaa ctgttggaac
    46381 tggtgtaggt atagtagtaa aagcaggttg tgcatcagga ggagacgatg ctttagcatt
    46441 agtaatttct aagactacat ctttgaacat agggcaagtt tatttagcaa cagatgttat
    46501 tgtattgttg ttatcattat tttatctatc agcgtttgat atcttttatt ctttgattgc
    46561 tgttacaatt agtggcaagg taattgattt tatttattat catggtaaaa gtttggatat
    46621 ggatataagt aatgatatag ttccagaatg ttaatataaa ttaaataact ttagatttta
    46681 ttaggggtgg cagatttgcc accttttttg tgtctaaatc tttatagaaa gtataatccc
    46741 atctaggttt ttgcaaatct caaatataga attatgttgg aatgactggg aatacgattg
    46801 ccagatgtgc attttaaaaa ccaaatttta tatttatgaa atactaatca ttaatggatg
    46861 tttcttaatc ctatctttat acctaaaatg ataagataaa tgaagtagca atacaaagct
    46921 aaaatttgta aaagagatta aattaaatgg aggagctaaa atgttggata tagttatgat
    46981 agcattgtta ttcataggat ttgtttccat gaagttactt gctgattggt gtgggaaaca
    47041 aactgaaaaa aaataatgta atgtatggag ggattaccta tgtggtttct ggcagttgta
    47101 attataatgt taataatata tttggtatat gcgcttatta atcctgaaaa attttaaaca
    47161 gtataaggct aataagtaag ttgaattggg gggaacaatt tttatggtgc agatagtaat
    47221 agtgttagcg atttttatga ttttagtaat acctatgggc aagtatttat atcatatagc
    47281 tactaatcaa aaaacatttg gagatagact atttgataaa gtggacaatt ttatatataa
    47341 ggtatgtagt atagataaga aaaaagaaat gaactggaaa cagtatgcat tagctttatt
    47401 atttacaaat gcagttatgg tatttatagg atatatcata cttagaactc aaagtatgca
    47461 tatttttaat ccaagtggaa ttaaaagtat ggaacaagga ctatcattta atacaataat
    47521 aagttttatg acaaatacaa atcttcaaca ttattcaggt gaatcaggac tttcatactt
    47581 tagtcagatg acggtgataa tatatatgat gtttacatca gctgcaacag gatatgcggc
    47641 tgctatggca tttgtaagag gtctagtcgg taaaaagaaa acattgggaa atttttatgt
    47701 agatttaatt aggataacaa caagagtact tttaccagga gctttaatta ttgggcttat
    47761 attagttaca caaggagtac cacaaacttt tgctgggaca gaaacagtga ctactataga
    47821 aggaaagctt caagatatag ctagaggtcc tgtggcagct cttgaatcaa taaaacattt
    47881 aggaacaaat ggtggtggat tctttggttc aaattcatca cacccatttg aaaatccaac
    47941 aataatatca aatatagtag aaatattatc tatgatgata ttaccaggag cttgtgttgt
    48001 tgcatttggt cacatgataa agaataaaaa acaaggttgg gttgtgtttg gcgcaatgtc
    48061 aatcatattt ttaataggtc tagtagtgtg ctttaaagca gaaagtgcag gaaaccctat
    48121 tttatcacaa ttagggctta atcaaagtat gggaagtatg gaaggtaagg aagttagatt
    48181 tggtatagca caatcatcat tattcacaac agtgactact tcctttacga caggtacagt
    48241 taataatatg catgatacac tgactccttt aggaggatta gtaccacttt taaatatgat
    48301 gctaaatgta gtatttggtg gtaaaggcgt aggtctgatg aatatgttga tgtacgctat
    48361 aatagcagta ttcttatgtg gattaatggt aggaagaaca ccagagtttt taactaagaa
    48421 aatcgaagga aaagaaatga agcttattgc tttacttatt atattacatc cacttttaat
    48481 actaatgttc tctggtcttt cagtagcaat accagcgggg cttgaaggaa tttcaaatcc
    48541 tggattccat ggattatcac aggtattgta tgagtttgca tcttcagcag ctaataatgg
    48601 ttcaggattt gaaggtctag gagataacac tatgttttgg aatataacaa caggtatagt
    48661 tatgttcttt ggaagatatg tgtctattat agtactacta gcaatatcaa gtttgttagc
    48721 atctaaaaaa gctgtaaatg aaagtatagg aacacttaga acggataatt ttacatttac
    48781 aatagtttta gtacttgttg ttttaattgt tggtgcttta acatttttcc cagccttagc
    48841 gcttggacct atttcggagc atctagtgtt gtggcactaa aaaattggga gggagtaaag
    48901 ttttatggaa actaaaaaaa caaagtttat tacaaaagat attttcaaaa cttccattat
    48961 agaagctttt aaaaaattaa atcctaaata tatgatgaaa aatccagtta tgtttgttgt
    49021 agaaattgga tttatagtaa cattgatact tacaatagta cctagtttgt ttggtgatga
    49081 aggcaataac ttaagagctt ataatgggat tgtaacaata atcttattta taacagtcct
    49141 ttttgcaaat tttgctgaag ctgtagctga aggaagaggt aaagctcaag cagatacact
    49201 taagaaaact agaaaagata cagtagcaag ggttatagat acgttaggaa atgaaaaaat
    49261 gataagtgca agtgagctaa aacttggtga tattgtttta gtaaatgctg gagaagttat
    49321 cccaaatgat ggagaagtta tagagggtat agcttctgtg gatgagtcag caataactgg
    49381 agaatctgca cctgtcatga gagaatcagg tggagatttc gcatctgtta caggtggtac
    49441 tacagttgta agtgactggt taaagataag aataacaaca aaaccaggag aatcgttctt
    49501 agataaaatg atagctcttg tagaaggtgc ttcaagacaa aaaacgccaa atgagattgc
    49561 tttaaatact ttgttagtag ggttaacact tatatttatg gttgttttaa tatctcttta
    49621 tccaatggca aactatgcag gtgtaaagat tccaatttct actatgatag ctcttttggt
    49681 atgtttaata ccaactacta taggtggatt gttgtcagct attggtattg caggtatgga
    49741 tagagtaact agatttaatg taattgcaat gtcaggaaaa gcagtagaag cttgtggaga
    49801 cgttgatact atgattttgg ataagacagg tacgattact tatgggaata gacttgcatc
    49861 agaatttata gcagttggaa atgcagattc aaaagattta ataaattatt ctgttatgtg
    49921 ttcattaaaa gatgatacac cagaaggaaa atctatagtt gatttaggta tgaaattagg
    49981 ttcaacaggt aagacaaaag aggcagagga agctgagttt gtagaatttt ctgcacaaac
    50041 tagaatgagt ggtattaact tagctgatgg tagagctata agaaaaggtg cttatgatag
    50101 cataataaaa agagtaaaag aatctggtgg tacagtgcca gaagatttag aagaaaatgt
    50161 aaatcgagta gctaaactag gaggaacacc tttagtagtg tgtgtagata atgagatata
    50221 tggaattatc tacttaaaag atacagtaaa atcagggctt gtagaaagat ttgctagact
    50281 tcgagagata ggaataaaga caataatgtg tacaggggat aatcccttga cagcagctac
    50341 aattgcaaga gaagctgggg tagatggatt tattgcagaa tgtaaaccag aagataaaat
    50401 agatgcaata aaaaaagaac aattagaggg taaaatagtt gcaatgacag gtgatggaac
    50461 aaatgatgct cctgcacttg ctcaggcaga tgtaggtctt gcaatgaata gtggtacaac
    50521 atctgcaaaa gaagcagcaa atatggtgga tttagattca gacccaacta agatattgga
    50581 agttgttgaa ataggaaaac agcttttaat aactcgtggg gctttgacaa catttagtat
    50641 agcaaatgat gttgcaaaat attttgcgat tataccggct atatttactc ttgcaatacc
    50701 tcaaatggag atattaaatg taatgaaact ttctacgtca tttagtgcga tattatcagc
    50761 tttaatattt aatgctataa ttatcccatg tttaatacct cttgcaatga agggagtaaa
    50821 atatagacct atgaaatcac aagctatgtt aatgagaaat atgcttatat ttggtcttgg
    50881 tggagttata gtaccatttt taggaataaa attaattgat ttattgatta cacctttagt
    50941 aatggttctt aatttaggtt aataaatgga ggatataaaa atgaaaacat taaagccagc
    51001 attacttgta agtattgtat tgttagttgt ttgtggactt gtatatccac ttgttttgac
    51061 aggtgtaagc caagttgcat ttaaagataa agctaatgga agtatgatag aagtaaatgg
    51121 tgtaaaagta ggttcagaac ttattggtca aagctttaca gatgcgagat tctttaaggg
    51181 aagagtatca tcagtaaact ataatactta tacaaaagaa gatttagtac cagataaaga
    51241 tggaaataca tcttatggag gtgtatcatc agggtctttt aattatggag ctacaaatcc
    51301 agaacttcat gatagagtgc aaaaagatat agaaaagttt ttaaaggata atccaactgt
    51361 caaaagagag gatataccaa cagatttact tacagcatca ggttcaggac ttgaccctaa
    51421 tataagtcca gcctctgcaa aaattcagat accagctata gcaaaagcgt ctggaatatc
    51481 agaaagtaaa ttacaaaaaa ttgtagatga taatacttcc aaaaaacttt ttggagtttt
    51541 aggtgaagat agagttaatg tactaaaggt taatgtagag gtcgcaaaaa tattaggtct
    51601 tatatagtat tttgtagaat tttagtaaca aaatattacg caagatttaa tttaaaggtt
    51661 aaattttaaa gagtgaaaat caataatgat tttcactttt ttatttgaat attactaata
    51721 tttggaataa agtgattgta agtataaaat ccaaaaaaag gttgcattat caaaatgata
    51781 atactataat atatttatcg ttatcaattt gataatagat ttggacatat aggaggaaat
    51841 agtatgttat ataataacgc attagagttg ataggaaaca cacctgtagt aaggctgaat
    51901 aatttaggct gtactaatgg gtgttctaac atatatgtaa aattagaaaa agtaaatcca
    51961 gcaggaagta taaaagatag agctgtttat gaaatgttag agggcttaga gcaaagagga
    52021 gaattaaaaa agggagatgt actagttgaa gcaactagtg gaaatactgg tattgcatta
    52081 tctatgatag gaaaattaaa aggatatgaa gtagtaatcg taatgcccga aacaatgagc
    52141 gttgagagaa gagatttaat gaaggcttat ggagcaaatt tggtgcttac agatggtaaa
    52201 gctggaatgg caggttccat agaaaaagca aatgaacttt taaaagaaaa tccaaactat
    52261 aaaagcctaa aacaatttga aaataaagat aatccaaatg cacattataa aacaacagca
    52321 gttgaaatta tgaatgatgt caaagattta gatatattcg tatgtggagt tggaacaggt
    52381 ggtactttaa taggaactgc aagatattta aaagaacaaa atccaaatat aagagtaatt
    52441 gcacttgaac caaaaaaatc tccagctata tcagaaaaca agactggacc tcataaaata
    52501 caaggaatag gtgctaactt tgttcctgaa aattatgatt ctagtgtagt tgatgaagta
    52561 atattagtag atgatgaaga tgcatttgat acagttaaat tacttgcagc aaaagaggga
    52621 attttagtag ggatatcttc tggagcaaat atatttggtg ctatagagat ggcaaaaaag
    52681 tatccagata aaaagatagt tacagtagct ccagatggag ttgataagta tatgtctatg
    52741 ggaatatttt aataatttta tttgagggag tgaatacttt gtttaagaaa ataaataaag
    52801 atattgaata tataatgaag aatgatccag cagctaggtc taagatagaa gtttttttac
    52861 tttatccatc agttcatgca atgataatgc ataggatggc tcatgctctt tataagaaga
    52921 agaagctttt tacagcaaga ttaatatccc agatatccag atttatgact ggcatagaaa
    52981 tacatcctgg tgctaaaatg ggggaaggta tattgataga ccatggaatg ggtgttgtaa
    53041 ttggagagac agcggaagta ggtaataggg tgacaatata tcaaggagct actttaggag
    53101 ctacaggaaa agatactgga aagagacatc caactgttgg tgatgatgta ttaattggtg
    53161 ctggaacaaa aatactagga cctttaaata taggttcaaa ttcaaaaatt ggtgcaaatt
    53221 ctgttgtcgt taaggatgta cctaatggtg caacagttgt tggtatacca gcaaaaatag
    53281 taaaaataag aaacctagaa cctgtaaaaa agaataaaaa agaagtgtcc tatgagtatg
    53341 atgaattaga taatgtatat tatatatagg atttatataa ctataaaata aactttataa
    53401 aaattatttt aaaaggtatt tttttcaaat ttgaggacat aataaaaaag aactgaatgt
    53461 tacagttttg gttcatcaat ctttgataaa caagatttta aatttgtagc gtctaggagg
    53521 attttattat gaaagcaaat gttaatcaag atacttgtat aggttgtgga ttatgtccat
    53581 caatatgtcc agaagtattt gatatgaagg atgatgggaa atcacatgtt atagttgatg
    53641 aagtaccaag tgatgctgaa gaatcagcag cagaagctag agaaagctgt ccagttgatg
    53701 caatagatgt gcattaataa aataaatgcc tataaaaatt gaattttcaa tttttatagg
    53761 catttgtctt ttattcagtt agtatttcaa cacctgtttc tgtaactaaa accatacatt
    53821 cccattgagc agataattta ccatcttttg tataaatagt ccaattattt tcttcatcaa
    53881 caaaaatttc gtgagttcct tcatttacca taggttctat tgtgaatatc atcccaggaa
    53941 ccaatagcat ctcagtccct tttttggata cataacttac aaaagggtct tcatgaaagc
    54001 ttaatccaac tccatgacca cctatttctc taacaacaga gtatccattt ttctttgcat
    54061 aagagttgat agcatcacct atatctccta aaaatcccca tggtttggca acttcaagac
    54121 ctttttggac acattccttt gtaacttgaa ctaatttttt tgcattttca ttaacattac
    54181 ctatcataaa cattcttgaa gcatctgaat agtatccatt aaaaatagta gaaacatcta
    54241 catttataat atctccatct tttaagataa tgtccttact tggaatacca tgacaaactt
    54301 cattatttac tgatgtacat acacttttag gaaatccatt atagtctagt ggagcaggga
    54361 tagctccatt ttgtagtgta aagtcatgaa ccaacttatt tatatcttct gtagacattc
    54421 caatttcgat tttatctgaa atataatcca aaatttttgt gtttattaca gcactttttt
    54481 ttatttcctc aatttgactt tcatttttta taatatcatg agttggtaca atatgaccta
    54541 acttagcaaa tgaatctatt ttattatcca tatccatatg acatttttta tattttttag
    54601 tacttccaca ccaacagcta tcatttctat ttaacttcat aacttttcat ccttctttta
    54661 ttatttattt aaattatggg ttacataaac tattttaaaa cataaccatt ataaatatta
    54721 taacataaat actaagaaat cctttataga tagtgattta ttcaaagtat aaattattat
    54781 atggttattg ttgatgaaaa gaggatagtt aaatgtatta ttggatatta gcgcacttaa
    54841 tagtttagtt caagtttttc aagaaaatca tatgttagag gacaattttc ctttaaagta
    54901 ttttttgaat cttcatcaag ataataatgt acaaatgatt ctgcaaaaaa ttcttctata
    54961 aacttgctta tatatgcatg tgcaacttgc ttagggtcat aaagcttata tctttcctga
    55021 gcaaatactt ccataaattc ttcagaattt gattttttat ttaaaacatt tttatctata
    55081 gcatgtgcag tttcatgtaa ttctaaattt tttgatgaat gtacatttgc atagctagga
    55141 ttactataac ctattttagc cactatagaa ttatttctat atataccagg tacatctttc
    55201 caagtcttgc ctgatcttac ccaacatgga ggtaattgat attttaaatc actaaattct
    55261 ggttcatcag ttagatttga atttattaat tttattttta tatccttttc tttaagtgtc
    55321 tgtaaatatt tactatttat ttttgcaagt ctgtttttca tattttcaac ttcatcttta
    55381 tcataattca agtcatcagg aagtataagc atttgttcaa ttatatctat actactgtct
    55441 tttatatttt cagattcttc atcaaattta tattgaagag tattattttc atagatagtt
    55501 atatttgtat tattttctat agaataagag tgaatatcct ctaaatctaa aatattcatt
    55561 tgttgtaaaa tatgttttgt ttcgccactc catactacta aagaaagtga attaaaatta
    55621 attagtggat tttcttttgc ttttatatca ttgcttatat ctacatcaaa tacatattca
    55681 attgagtctt ctatgttaag actatctgta ttctttttaa tatataaata cgcttgtttt
    55741 aagtctatat aaatctcatc taaagattcg tcataaaatt ctgataaatt attagtaaag
    55801 agttcttcac ttaaaagttc atttttatca gttatacttt caattaaaat attaatttct
    55861 tttatcatat cgtaaatact tatttttcta tttgcttttt cactagatac attgcatggc
    55921 gcaagagcaa tgcaataaaa atctttttct tttttataaa aggctttaag tgattttgat
    55981 aaaagtgtaa agtctacacc tatctgtaag ttgaccttaa gtgagtcatt ttgtaataat
    56041 tcagtattat ttcttttagc tgtatttaaa ttgttttcca taatcattgc ccccttttta
    56101 ttagggtatc ataatttttt tatatgtgtc aatttgtttt tttgaaaatt ataatttttt
    56161 tgaaaatttt attttttata atttgtgaat tttttattat agaaataaat atgttattat
    56221 tatgtcaaaa tttagcatta gattcatgta gagtatgttt tatacatata ttataattaa
    56281 ttctttgaag attgcatatt caaaatacac accatttttt ttaattctat aatataatat
    56341 ttatatattt aatgttagga tgtgatttaa ggtgtatttt acatatatta taagatgtaa
    56401 agatgattct ctatacactg gatataccag taatatagtt agaagaatga atgaacataa
    56461 attaggaatt aattcaaaat acacaagagc aaagggattt gaaaaactag aagtttattt
    56521 tgtgaccaac acaaaaagca atgctatgaa gttagaatat tatataaaaa aattaactag
    56581 aaataaaaaa ttgtctataa taaaaaaccc aagtatactt ataaatttaa ttgataataa
    56641 agaagattat attattggta aggaaataga acaattaaca taaatattta tagtaacatt
    56701 ataatgggtg catatggtgt aaaaacttga caataaatac tattgtaata taatgaagtt
    56761 ataaatatag taaattaaaa tagctagggg agccaagagc tgagaggtat accgaccctt
    56821 acacctgatc tggataatac cagcgtagga aagcttagta aaaattcaag tatgtattat
    56881 ttgtgatata tgctatttct aagctatacc tattgtaggt atagcttttt taattaagtt
    56941 atttaaatta aactttagga ggcaacaatg agtaattata aaataccaac acttacaata
    57001 gctggatctg attcatctgg aggagctggg attcaggctg atttgaaaac gtttagtgcg
    57061 attggtactt atggtatgag tgtaataaca gctataacag cacagaatac taaaggagtt
    57121 tttgctgtag aggatttaaa taagaaaata ataaaaaaac aaatagaggc agtctttgaa
    57181 gatatacctc caagagctgt aaaaatagga atggtttcaa gtcctgagat tatacttgaa
    57241 atagttgaga atctaaagaa atacaatcca aaatatttgg ttgtggaccc agtaatgata
    57301 tctaaaagtg gatattatct attaaagcca gaggcaaaag aaaacttaat taagtatttg
    57361 ataccacttg catacataat tacaccaaat ataccagagg cagaagaaat aacaggaata
    57421 aaaatacata atgtagatga tatgaagaga gtaggagaag aaatactaca acttggacct
    57481 aaatttgtgc ttatgaaagg aggtcattta gatggagaag cagtggatat tttagttggt
    57541 aaaaatatat ttaaagttta taaaagtgaa agaattgata aaaaaaatac acatggaaca
    57601 gggtgcacat tatcttctgc aataacatct tatctagcat taggatatga aataacagaa
    57661 gcagtaaatc taagtaaaat ctatataaca gaagcaataa aaagaagttt tgatataggt
    57721 catggagtag gaccagtaca tcatttttat aaatttgagt aataaaaaaa tattggaggt
    57781 agaatatgta taatttaatt aaagatgtaa aaaaattaaa tccattggta attcattata
    57841 ctaataatgt aactataaat gattgtgcta atgtaacttt agctgtagga gcaagtcctc
    57901 ttatgagttt ttcatatgag gaagtagaag aaatggtaag tgtagcaaac tctgtagtaa
    57961 taaatatagg aactatgaac tcaaatatgt tggatttatt cctattagct ggaaaagcag
    58021 caaataagta caataaacct gttgttttgg acccagttgg agtatttgca agcaaagcga
    58081 gagcagaact tacaagtaga cttttaaatg aagtcaaatt tagtgttgtt aaagggaatg
    58141 tatcagaaat aaagtttata ggtggcttta atgtaagggg taaaggtgta gattcatttg
    58201 atgaagaaga agattctact gagataataa gaaagattgc tgaaaagctt gaatgtgtag
    58261 ttgtagcaac tggaaaaata gatataataa ctaatggtaa aggtacatat aaaataaaca
    58321 atggaactga taaattaaaa ggaattacag gaactggatg tatgactgct agcttgattg
    58381 caagttttat ggctgttact gagaatatat tagaagcagc aacaatgggt gttcttacaa
    58441 tgtctttaag tggggaatta gctaatttaa ataatccacc aataggtaca tttaaagaaa
    58501 atcttatgaa tgctatttat caaatggata tagatacttt aagtaaaaat tctaatattg
    58561 aatttttaaa ttaataaaga gtaagggaga cttaaaatga ttgataaaga atctttaaaa
    58621 aaatgtttaa agttgtattt agtaactgac tctgaaatgc ttaaaggtag agacttttat
    58681 aaatgtcttg aagatgcaat atcttctgga ataacaactg tacaacttag agaaaaaaat
    58741 gcttctggaa gagagttttt aagaaaagct atgaaactta gagaaataac taaaagatat
    58801 ggtgttaagt ttataataaa tgatagagtg gatatagcac ttatttgtga tgcagatgga
    58861 gtacatgtag gacagagtga cattgatgtt agagaggtta gaaagcttat aggaaacaat
    58921 aaaattctag gagtatcagc aagaacttta gaagaagcta tttgtgcaaa aaatgatggc
    58981 gcagactatt taggtgtagg gtctatattc acaacatcta ctaaattaga tgcaaaatca
    59041 gtttcgtttg aaactgttaa agaaattaaa gaaaaagtag acatgccatt tgtactaatt
    59101 ggaggtataa atttagacaa tatagataaa cttaaatgtt tagaaagtga cgggtatgct
    59161 ataatatcag ctatattaaa agctgaagat atctctaaag aagtggaaaa gtggacatta
    59221 aaaatataaa attggctctg gtagtgaaaa aaatggaaaa atttgatata atctaagagt
    59281 aaaatttaag caattataaa tgataaactt ttctacatat actttttaat caagatatat
    59341 gtagatttgg ttaaaaagga gctataaatg attaggatat tgttagtgtg tgttggaggc
    59401 atgtcttcta ccctattggt aaataaaatg gagaaggatg caaaaaaaag aaatatagac
    59461 tgtaaaatat gggcagttgg agaaggagat ataaaatcgg agcttgataa ctttgatatt
    59521 ttacttcttg gaccacaact tagatttatg cttgatgacg taaagtctat agttggagat
    59581 agagctccag tatctataat agatatggta aactatggca cttgtaatgg tcatgctgtg
    59641 ttaaattcgg ttttagaaat attaaaataa ataataaaag tggattctat ataatagagt
    59701 ccatttttat tatttgttat taataggctt aaaacttagc ttaccatttc tttttttaat
    59761 ctccacatag caagtgaaaa acttgaacag cacaatatta aaaatagtag gataacaggc
    59821 agtatatctc caataagaat agtctcacca aatattaagc tacgtaaagc gttaataaca
    59881 tgggtaaatg gattgagcat cactgctact tttaatcctc cagataaact ttctataggg
    59941 aaaagagctg aacttaaaaa gaaaatagga agtacaattg cagtcataat tgtttcataa
    60001 actatttcat ttggcaataa taaacttata gaataagcta gacttgataa aaagaaggct
    60061 gtcataaata tcagtactat cataagtagg attccaccaa tgccagattc tatccttact
    60121 gagaagaata tacttactat acacaaaata gttacttcta tgaaagaaac taagatagct
    60181 tctaataatt gaccaaggac gattgaatac ctactgatag gtgcaattaa gactctatag
    60241 aaacttccac tgttcttcat tataaagttt ataataccac cactactaca agaagaaaac
    60301 acaaccagta caatgatacc tggtagtata aaagcagtat aattattgat atttatatta
    60361 ttcatagttt ggtttgcaat agaactataa agcacaagcc aaagaaaagg ttgtaatata
    60421 gtaactacaa atgagattgg atttttaaaa cgccacttca tactacgcca taagatattt
    60481 aacattccca ttcctccttt aagctttttt tagaacttgt aagtgctaaa aatacatctt
    60541 cgagacttgg ctctacaatt tctattgcat caaattctat atcatgttct aaaagccatt
    60601 tatttattaa agtaaaagca gttctactat cgtttacact tataaaaatt gaattttctc
    60661 gtacgctcat aaactttact aaaccagtac ttttaattgc atctttatat ttttttatat
    60721 cttcagtatt atggaaagtt atacgtagta tattttgtct aatgtaacta cgtaaacttg
    60781 atggtgttcc ttgtgctaaa tcctttccat tcttcataat acaaatatta tcactcaatt
    60841 gttcagcttc ttcaagataa tgagtagtta gaaatatagt tgtgccatac tcatctctaa
    60901 tttttaataa catatcccac atagattttc ttgaatcgac atccatacca acagttggtt
    60961 catctaaaaa taggatttta ggagatgata ccatattcat agctatgtcc aatctacgtt
    61021 ttacaccccc tgaatatgat gaagtaggat attttaagta actagataag tcaaacttat
    61081 caattaaaga gtctattctt tgttttgcaa tctgtggttc tactttatac attttacttt
    61141 gaaataccat attttccata agggataaat gttcatcaat agagatttgc tgtgctacac
    61201 aagcaatttg agtacgtatc caagaaggat tatctactaa atcttttcca aacattgtta
    61261 catttccaga tgtaggtttg taaaaggtag tcaaaatatt tataagagaa gatttaccag
    61321 caccattagg accaagtaaa gaaaaaattt ctccagcatt tacattaaag cttagagcat
    61381 ttaaagcttt cacaccattt ttatattctt ttactaaatt gtctatttca atcgctaaca
    61441 tatattattc ctcctcttta agtggaaata ttatctctgt aatatagtta tctgggtttc
    61501 cttttatcaa catacctggt cctttaataa atacttctct ccaaggagtt tgtattttta
    61561 tattattttc atgaatatat ttaaatatca tttcatacgt ttttggaaaa ttactataag
    61621 agcctgtgtg agtaaaaaat aaagcttttg ttttaggaaa ttcttttgta gttataccca
    61681 tacgatttgg agtttcagca gttggaacac ataattccat ttctgcaaca ccagtttttt
    61741 ggtcaacatc atagtagcaa aagaatggtg caccgttaga ctttcctttt atagctttaa
    61801 atacatttgg aaaatacttt gttgcctcag tcataggtcc attataacgc atggtagcca
    61861 ctgtgactga ttcgatattt ttgatttcaa ttttgcaatt cattgtttac ctcctaatgt
    61921 gtgttcatat tcttactaga tttttaagca ttaatacata taagattttg attagttgaa
    61981 aacatataat cttatctcgt ttgcttgttt tcaagtctaa cataacataa aatatatatc
    62041 ctctcatttg atgctccatt ttgtaaagtt attatttaag ctttacttta gattttttag
    62101 caaattaaaa taaagcaatt tataaaataa gtatttacaa attaagtgta ttaatcgtat
    62161 aatacactta ataggatact agataaagtc tgaaataaag gcgtattttt ttaaagtaag
    62221 tgtactatcg tattaataca ctagaatagg aggaatcatg aattttgaat tagataatac
    62281 aactcccatt tatttgcaaa tagtaaagta tataaagaga caaatagtaa caggagagtt
    62341 gaaaccagga gagacaatac catcaagaag agaaatggca cttaatctaa aagtaaactt
    62401 aaatacagtt caaagagcat ataaggagat gggtgatatg aatataataa atacttttaa
    62461 aaattatcaa agcagtgtaa cagttgatga aaatatatta aaaaatttaa aattagagct
    62521 tataaatgaa tcactatctg tttttataga agatatgaaa gcaataaatg ttagcaaaga
    62581 agaagtttta aaaataatag aagataagta ttagtttttt aacaaataga aaacttagtt
    62641 tagaaagttt atttataagc atattggatg tggaggatag taaatatgat agaaataaag
    62701 aatgtcagca aaacatataa aaggatgcaa gggcttaaaa taagaaagat agaagcttta
    62761 aaaaatgtaa gttttaatat agaaaaggga aaaataactg cattacttgg tataaatggt
    62821 gttggtaaat caactatgtt aaaagcaata gcaggactta taaacattga tagtggagaa
    62881 attcgtatag atggagaaaa aataaatgaa aaggtataca ataaattggc ttttgttcca
    62941 gatgtacaat ctcactttag caatacaaca ataaaagaaa catttgaatt tatggaaatt
    63001 ttttattcaa agtggaataa agaaaaatca aaagaaatga tggacatatt taaattggat
    63061 gaagatgaaa taattgataa cttgtcaaaa ggaaacattg caagagtaaa attaatactt
    63121 ggattttgcc aagacccaga gtacatactt cttgatgaac catttacagg aattgatttg
    63181 tttaagaggg aagagtttat aggagtaata gcgcaatata tggaggaaaa tcaagccatt
    63241 atcataacta ctcatgagat agtagagata gaaagtttag ttgatgaggt tgtaattctt
    63301 gatgaagggc agattataac ttcatttaat gcagaagaat taagagaaag agaaggtaaa
    63361 tctatattag ataagatgag ggaggtatat aagaatgaat aaacttctat atctaataaa
    63421 tgtagatttg agaagaagca ataagtttta tatagcttat atatcatttt tttcactaat
    63481 tacacttagt ttaaatttat tcgaaattaa taaatttaaa aattctaaat ttattatgaa
    63541 cttagcaata gaagattttg gaggtatatt ttatggacta gggatactta gtaatcttgg
    63601 ttttatccaa agtatattgt tctttgggat attgggactt tttatatact atatttttat
    63661 gtggaaaaga gagttctttt caaataatca aagtatttat acacttatga tgttacctca
    63721 aaataagttt aagatttgta tatctaaatc aatagctttg ataacaatga tatatggttt
    63781 tttgataagt cagacagcaa cattatttat atgtaaatat atatttaatt tcatttttag
    63841 aaatatgcct ataatcaata tgaactttgc caaagattta tattatttaa acttgaagag
    63901 tataccaatt gattttatct cttttatggc tatctatgta tttttactac ttatagctat
    63961 ttctattgta aattgctgta tattatttat cttttcctat ataaataaat tttatgtaat
    64021 tttaatcact ttgctgatta tagcaggctt atatttttca acaatatata taaatataat
    64081 cactttattt agaaaatatt atagtcttat aggatttcaa tttaacaatt tagtagcagg
    64141 gttattaagt tttttaatta taatgtttat tctaaatgga atatcttatt tgctaattaa
    64201 aaagaaagta tctctttaag gaggggtggt atgaaattaa aatctaaaat atctatactt
    64261 attatatttt tgactttagc aatatatttt agtataggtt tattaaataa tgaagataat
    64321 ttaaagataa aaactataaa aggtgactct aatgaattag accatataaa cataaatttt
    64381 ggatatgctt tgaatggata tataaattca tattatacaa taaatggaag taacaaaacc
    64441 aaaaagactg aattaataaa actacaaaag gatagtaaga acacaaataa tttaattgat
    64501 gtatctagtg gttcagattt aattgcacat gttggatttg aaatgaatga ggagtcaaaa
    64561 gatataaact ttgtaataga tgagaaaaaa gaagatttag aaaaaggtgt atttccatca
    64621 gaaggaagtg ataaagaaat tgaatatgaa aaattagata tgaataattt tacaaggaca
    64681 agatataaag tagataaaag tacagatgat tattatgcaa atatactagc atcaaaaaga
    64741 tataaaaaat acttatatgt atctgtactt tatgctacaa gtgattcatc agaaaataac
    64801 aaagaatatt caagtactat agatataata aaaattaatc cagaaaataa aaaaatcaag
    64861 actataaaaa gtataaattt aagtaattat ttttccgaaa aataccaaaa catagagacc
    64921 ataggtgtaa gttatgctag caaatatgag gataagatgt atattttagt aaatgtacta
    64981 aatacaaaca taggtgataa tagtaattct aaatttcatt tacttgagta taatcttgaa
    65041 gaaaataagg aaagcataat ggaattaaaa actgatagca aaatggcttt agcaaaagca
    65101 aagttagaag ctaataaatt atatatggta atgtcgaatg attatgataa tagttcaatt
    65161 acagagttaa atttacttac ctataatata ttagataaaa gcttagatga agataaatat
    65221 gttttagata atagagaaaa aagaggaatt agaagtattg aaattgattc aaataaaatc
    65281 gttgcatata catcaaggct aaactctata ttatcttggg ataataaatt tatgctatat
    65341 ataataaata aaaattctaa ggaaattgta tatgaaggag aattacaatt taacagttca
    65401 aatagtatgt tagaatttga aataaagtag gtgagttgat gaaagattta ataagattat
    65461 tcgaatttga actaaaaaga aatataaaga attatatatt tataataatt tgttgttgtt
    65521 cttttgtaat tttaaacata gtaaaaaatt taaatgacta taattacata atagaaaatg
    65581 cagttaaaag tgaacagtta acaaaaatcg gaaatacgat agaaacggta aaggttacag
    65641 gtttctcaag ctttagaaat ataatgggtt ctacagaatc gtggtttatg tttggtataa
    65701 ttgcatgtat ttgctattct ttttttattt ggtatagaga ctttaatggt aggagtaaat
    65761 ctatatatac acttataatg ctacctaaaa atagaatcaa tatttatata tctaaattat
    65821 taaatatatt atttctagtg tatagctata cagtagtact tacaatatct ttgtttattg
    65881 caagtaagtt gttgcctaga catatgcttg gtaatgtcac aaactatggt tttgtacaag
    65941 aaacaatata tgagttaaaa atgttacttc catatagctt tgaaatacta tttgtagagt
    66001 atatattttt attgatagga tttgtatctg tagtatttac atcaattctt ataaataaat
    66061 ctatttataa agtaagcact ttaataagtt ttctattttt agttatagaa attttagtgt
    66121 ttataatttc tatagaattt attataccct acgaatacag tgatgtattt actgttctat
    66181 attcaagtat aaacatattt gtatgtagtc ttatatctaa taaacttttg aagcaaaaga
    66241 ttgactttta ggagggatat tatgaaagca aaaaatatag gaaaatatac aatatgtttt
    66301 ataatagtat gttttttaat gattactatg accttaatat tgagttattt taataaggat
    66361 aaactatctg taaaaacttt aaaaggcaat gtaaaagata tagggagagt aagtgtagta
    66421 tatacaccta atataagcaa attttcttat gaggaggtaa ttataagtaa aaatggagta
    66481 agaaataata caaacccaaa atcaagaatt agaaatgatt atttaaatat tgacaaaaaa
    66541 tacagtgact ttgttaatga taaaggaaaa gaatttatat ataaagatga tttgaatata
    66601 ggagaagcgt atacctctgt taagtctgat ttagtacaag gaatgaatgc tttaaatgat
    66661 tgtataaagg tttcaaataa aaatttaaaa agtggggtag aagaaaattt tgatattaat
    66721 ttaaataagt ctgattttaa agaaaatagt tggaaaacct tatttaacaa aatatataaa
    66781 ggtaatttat atatggtaat tagtgaaact aatatttcag gttctaaagt caataatatt
    66841 tgtatactaa agatagatat aaaaaataag tcttataaat tattaaatag atttaattta
    66901 ggattacaga atggagaaca acaaaatatc aatgaaatta aattttctat tggaagtaaa
    66961 ttatacttag aaatagtaaa taataaaagt aaaaatggat atattgaagg acatgatagt
    67021 tactctaact ttattatata tgatatagaa gataacactt ttaatataag taataaattt
    67081 atggataatc taaacaaaga aaagaatgca aatccaaagg agattggctt attaagtaaa
    67141 actaagctag attatatggt aaaaaataat aaattgaatc ttatagttac ggatatgagt
    67201 aattccataa ctaatcttgt ttatgatatt aattctaatg agattaaatt agaagattat
    67261 gagatacttg atttaaaagt agattataat gaagcatcat ctggagttag gaaagttaag
    67321 ctactggatg ataagatata ttctatttca ggtattaaga acagtatatc aggagaatta
    67381 aaaggattta aagggattgt tgatgtagtc ggaactaagc cagtaaaatt tcaagtattt
    67441 gatatgaaac ttaaaaagaa tatttatgaa gctgagctaa taaatggaga tataagttta
    67501 caagaaaagt tattttttgt tgcaaattaa gtgttagaat taattttaga actttaaact
    67561 tttatatgta tcacagataa gtataagtaa gggagtgtct caaaataaac tttttagctc
    67621 atgagacact ttttttatat gaaatcaaat atattttcat tgtttagatt tattttgata
    67681 atgaaaaaaa gattatcttt attttaagaa agacatttat ttataattat atacaaaaat
    67741 attttttaat gtttttgtgt ataattataa caatttaatt tatattaatg cacttaaatt
    67801 tgaaatagaa tgcttatagt ggtaaaatta attattagaa tattagaaat aataaataaa
    67861 taatacattg tacttaaaag ggggagaaat ttaagatgaa caaaaaatat attaaagcag
    67921 ggaatttaat tgatggaacc ggaaatagta ttatgcaaaa taagggtata attattgatg
    67981 gagatactat agttgaaatt gaagatataa gagatgattt aaatggatat gatgtgtacg
    68041 attacttaga taaaactgtt atgccaggca ttatgaattg tcatgttcac ttgacaatgg
    68101 agccagttgg aaatccaaag atatattatg ataatgtatc agatgtagag cttgtagtaa
    68161 atacgataaa acaacttgat gcttatttgg attcaggagt aacatatatt agaagcttag
    68221 gttgtcccaa atatgtggat gtacaactta aaaatcttat agacaaaggg tctatagatg
    68281 gtcctggtat agttacttca ggtccagtta tatgtatgac aggagggcat ggatattatt
    68341 ttggtattga aagtgatgga gtagatgaat gtagaaaatc agccagaaca gttttaaaaa
    68401 atggagtaga ttgtgtaaag ataatggcaa ctggaggtgt aacaactgat ggagttgagc
    68461 cagggtcacc acaattaact ttggaggaaa tgaaggctgc tgtagatgaa gctataaaag
    68521 caggtaaaat aactgccaca catgcacaag gaagaactgg tataaaaaat gcagtgcttg
    68581 caggaattac ttctatagaa catggtgttt atttagatga tgaaataatt gatttgatgc
    68641 ttgaaagagg aacttactta gttccaactg tggctgcacc atattttatt ctaaatgcag
    68701 gaaaagaaag tggaataact gaagctactc ttagaaagtg tgagattgtt gccattccac
    68761 acaaagagtc attcctaaaa gcatataaaa aaggaattaa aattgcagtt ggttctgatg
    68821 caggaacttc ttataatgaa catggaaaaa catattatga aatgaaacta atgtcagatt
    68881 atggtatgga taatatggat ataatagttg ctgctacaaa aacagcatct gaacttttaa
    68941 gaattgataa aaattatgga actctagaaa aaggaaagaa agcagatgtt atagttgtaa
    69001 atggaaatcc agtagagaat atagacgtac ttgcagatgt gttagcagta tttaaacttg
    69061 gtaaaaaagt tagataaata gtataaaaat aaaaaagagt gtctaaagaa atttttaaat
    69121 aattatagac actctttttt attagtaata attaaatctt ttatacttta gaaaatagat
    69181 tctattttat atttagatat aactctttaa aatcattctt atgcaatata atctatagaa
    69241 tctacacata caaagtatat tcttgaatca ttagaatttc caagtactat aacatcattt
    69301 ttcttaccta gaacttcaac accagttaga accaaactac cagctactac agtaacttga
    69361 ttatttatat ttgacatata aagattatct aggatacctt tattacaaca gcaatcatca
    69421 caatcgcagt tgcaattaca ttctttgtaa tgttttttat caagatagta acctaaagat
    69481 gctatgaaat cttcataatc tgcaggtgta atatcaaatg caacagcttt aagattacac
    69541 aatgatgcta aatctacgtt tgctaatgga gtagatgcag caagtataaa atcaattata
    69601 gcagcaagta ttgcatctaa tatagcccca aggtctatcg taggaggaat aactgcatca
    69661 ataagtgcaa ttaattcagc tactcctggt atagttccta tagtattaat taatccctca
    69721 agagttaaag ggactggaat aggataagat actctaccag ctatatctat taaatcacag
    69781 ttacaagcag aaaatctttc aaaagtacca tcaagtccag ataaattatc ttttggagga
    69841 gctgaaagat ctatacctac caaattagca cctactataa agaaatctga gataaaagca
    69901 aattgattaa agtttacaaa aggtcttaga gcatcatatc ttagaagttc taatgcttct
    69961 ctcatacttt ttttacaaca acattgtttt attttaggtt ctttatattt atttggataa
    70021 ttatagtatc tatcagctac ttgataattt tcatagtatc tttcatttgt atttggataa
    70081 tcttcctcat attcttgtgt aaatctaaag tcctctctac atttattatt ttccactaaa
    70141 tacactcctt ttatatttta atttaaatgt atagataatt aagcttatct atatagtaat
    70201 attatattta taatgtaaaa aaatgttaca aaagatatta taaacgaata aaaaataata
    70261 atttgtcaga taaacttgta aatttttatg aataatccat tctaaaacaa aaaactgtgt
    70321 ataaaaaagg tttatatgtt atatttatat aaatataaca tatgaacgag aaaggagtgg
    70381 tttgataaat gattgaggta gataaattgt gtaagtcttt tacaagggtt gtaaaagatg
    70441 ataagaataa aagttcaata agaaagctaa agaaagtaaa aactaaaaaa gaagaatttt
    70501 ttgctgtaaa taatgtttca tttaaagtta tggaaggtga aattgttgga atattaggtc
    70561 caaatggtgc aggaaagact acattactta gaatgttagg tggcatatta acaccaacat
    70621 caggaagtat aaatatttct ggatatgatt attcaataga tagaaattca gcaaaaaaag
    70681 aaataggtta tctctctgga aatacaaaac tatatggaag gctttctccg agagaacttc
    70741 taacaacttt tgcaagtcta tatgagatgt caaaagaaga tatagaagaa tcaattgaaa
    70801 atattgtaaa aataatggat atgagtgaat ttatagataa tagaattgaa aatctatcaa
    70861 ctggtcagac tcaaagaaca tctatagctc gttgtttaat acattctcca aaagtatata
    70921 tttttgatga gccaacacta ggtctggatg ttttaagtag tgcatctatt atagatttta
    70981 tgaagaatga aaaactaagg ggaaaaactg ttctttactc aactcattat atggaagaag
    71041 cagaaacttt atgtgacaag atttttatga ttcacaatgg gaaaataatt gcatcaggaa
    71101 caccacagag tttaaaagag gaatctggag taaataattt gagagatgta ttcataaaac
    71161 ttgccagaaa ggaggacatt taaatgagaa gtaagattgt aaaatacata tttaaaaaag
    71221 aaatgttaga catattgaga gataaaaaga ctttatttat gatgattgtt gtgccacttc
    71281 ttttatatcc tttacttatg ttattaatga ttcaagtaat gaatatgtct gcaagtagta
    71341 tgaatagtaa ggacattaat atagctttta ataataaacc taataaggtg ttagtatcca
    71401 tgattgaaga tgataattta gaaaaagata ctaaaaatac ttcaaatgat aaaggcaaaa
    71461 taagagtgtt agatgtagat aactataaaa agtcattaga agaaaataaa attgatgctt
    71521 atataaagat ggaagaaaaa aaatcatcta taaattatca aatatatata aattcttctc
    71581 aagaaaattc ttctaatgca ctaaaaagaa ttgaaactgt tttggataaa tataaaagat
    71641 ttaccataga aaaaacttta tctgaaaaag gattagatgt acaagctact ttagaaccaa
    71701 taacatatag cactgtagat gttgcaaaga cggaagaagt ggcaggatac tttttaggtc
    71761 agatacttcc atttatatta ataataggag ttttactagg ttcaatatat ccagcaatag
    71821 atgttatggc tggagaaaag gaaagaggta cattagaaac attatttaca ctgccaatat
    71881 caaacttaga actggttatg ggaaaatata tggcagtttc tcttagtgca atagtaacag
    71941 caattttaaa cattttatct atgggactga ctatggcatt tattttagtt agtggaggta
    72001 ttagtagcca atttggcttt ggaaacttta attatggaga cttagtctta ccaattataa
    72061 ctactttaat ttgcatatgt cttttttcaa tggtagtttc agcaataagt atgtgtgtat
    72121 gttcattagc aaaaagtttt aaagatgctc aaaactacat aacacctctt atgttaatta
    72181 ttatgatacc atcatatgtt tctatgatac caaatatagt attagataga gtgacagctg
    72241 taatacctgt agtaaatata tctttactta taaaaagtgt attatctttt aaaagcgatt
    72301 taaatttaat agccttagtt ttagcatcaa atgtagcctt tgttatattg gcaatcatac
    72361 tactgtctaa gatgttcaat tctgaggaaa tactttttgg taatagtaag agtttttctt
    72421 tcttagagaa aagaagtaat ataaaaaaag ggtctatacc aactgtaagt gatggtgtta
    72481 ttttatatgc agtaggatta gttctattga tttatgttgg ttctttagtt caaattaaat
    72541 ttggtatggc aggtattata atgacacaat tcatgataat ttctttacca ttattatttg
    72601 catactatat taaagctgat tttaaagagg tatttagctt gacagttcct aaattaaagc
    72661 atgtgtttgg gagcattgtt ctttggattg gtggatacat acttattatg attataacac
    72721 agctaatttt attcttattt cctcaaaata tggaagttgc tgaaagttta aataaggctc
    72781 tttttatcaa agatagtgtt ttactgaatt tactagcaat agctttatta ccagctatat
    72841 gtgaagaaat gttttttagg ggatttatat tttcttcatt tagtaaatca aaagataaaa
    72901 ataagtctat caaactcgct ataatatgta gtggggtact atttggtatt atgcatatgg
    72961 attttattag aataattcca acatcaatat taggtattat atttgcatac agtgtgtata
    73021 aatctggttc aatatttgta tcaatgttat tgcatttttt aaataatagt gtagcagttg
    73081 tgttaaatca ttatacaact ggaaatataa ccaacttata taaatttgtt gaagttgatt
    73141 tttcgaactt aaatgtgctt aaatttgcct taattcttct aataagtctt atattaatta
    73201 tgttaggatt aagagtttta gatagaaagt ctttaagaaa ttaagtataa agttattata
    73261 tagattaaaa tattaataag cactaaagta tatggatata tcttgtatat aaaaatactt
    73321 tagtgctatt ttatatattt taattatatg aattatttat cgtttcattt atgtaatgaa
    73381 aatgttatat aaatgaaaca ataaataatt tttattttag aaatttatat ttaaataatc
    73441 aagttgaaag tgagatacta aaaaaattaa tttaggaatt atttgattta ttcatttata
    73501 aaaattaatt actgatttgt cgaaaccat
//
LOCUS       DAFAZV010000020        67688 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFAZV010000020 DAFAZV010000000
VERSION     DAFAZV010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 67688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67688
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.020"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..494
                     /locus_tag="KOU88_001879"
     CDS             <1..494
                     /locus_tag="KOU88_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HBK3211771.1"
                     /translation="GSFGSIEDMIDGLFEKDGAFNMLNNSYYNLPINNPSYKKLVELI
                     RDYSNLPILNHCTAGKDRTGVGSAIILMILGVSRENIMKDYLKSNDFADKEIERFIEY
                     KPKFKDIPKENLKYIFGVNEEYMKTAFRRIDEEYISVEAYLYGEFNLNKEEIRKLRNQ
                     YLE"
     gene            506..2284
                     /locus_tag="KOU88_001880"
     CDS             506..2284
                     /locus_tag="KOU88_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3211772.1"
                     /translation="MSLNITARQINIIKILLNSKDTISGIALSQEIGCSSKTIQNEIK
                     DINKQLRNGKILSIRGVGYKLEGSFDEVNLNSNLYDDVDRVEYIIRKILTLSNEEKNT
                     IKLEDLADSMYVSVSTVKNDLKEVKRILEKYSISVKSKHKQGICVLESEDKILNCIVD
                     LSNKRDNQLSLNDFLNDDIKERKLLIKKLLLDILNENGLVLTDIEFKSVLNNILVMLS
                     RHKYNEKEFIENYIENYRSKRSSILENEQNKEIIINSIKTFCKNLKLATSIDISNDKV
                     FEEFLYKHISSLCKKIKLGINQSPIMAQDIKIKYPFAFELANIAKKTIEKDLKIEINE
                     DEVANIALHIGGAVERASYNNKDKVFKTIIVCTSGIGTSMLIKAKLENIFKEKLEILK
                     IIPSYLVEYIKVIDVDFVISTVPIEVGDVPVINISPILSEKEIRLIEKYIETGNIYLD
                     LDIKSLFDSELFFTDLVFKRKEEVIDFMASKLVQKGYIDEDMKKSYFEREKIATTEIG
                     NMVTIPHGAIGKIFDNKIAIGILKKPISWEISDVRLIIMLALDKDKILDYEVIFSKIY
                     KRVDSIAKVISICENSSFEKFVNLFN"
     gene            2451..3368
                     /gene="pfkB"
                     /locus_tag="KOU88_001881"
     CDS             2451..3368
                     /gene="pfkB"
                     /locus_tag="KOU88_001881"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBK3211773.1"
                     /translation="MIYTVTLNPSIDYIVKLDELKTGSTNRVKEEYVYPGGKGINVSR
                     ILKELGNDNTSLGFISGFTGEYIIRTLEEKELKTDFIKIKSGFSRINVKIKALKETEI
                     NGQGPNIDDEDIDTLYKKLDKLNQDDILILAGSIPSTLDEKLYENIMARLEKKNIKVV
                     VDATKNLLLNVLKYKPFLIKPNNDELEELFGVKLNSIEDMVKYARRLKEMGAINVLVS
                     MGKDGALLITEEDEVLISDVPKGKVKNSVGAGDSMVAGFISGYLNTGKYDYALKLGAA
                     SGSATAFSYDLAKREYIDKLVNEISVKKF"
     gene            3405..5324
                     /locus_tag="KOU88_001882"
     CDS             3405..5324
                     /locus_tag="KOU88_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3211774.1"
                     /translation="MKIIDLLDEKSIKLNLNSKTKSEAIEELVDLVANSGNLNDKENY
                     KKAILAREEMSTTGIGEGVAIPHAKNSSVTKACIAAAVSKEGIDYESFDGSLSNLFFM
                     IAAPDGANNTHLEVLSRLSTILMDEDFRNKLINSSSEKEFKEIIDKKEREKFSEEYQD
                     EKVAEKNIIDTKENDANKYPKVLAVTACPTGIAHTFMAAESLNKMAENKGVSIKVETN
                     GSAGVKNKLTKDEIENATCIIVAADKNVEMARFNGKKVIKTKVADGIHKAEELIDKAV
                     NGDAPIYHGGDGSHNESNEESESGFRKVYKHLMNGVSNMLPFVIGGGILIAIAFLLDD
                     YTINPSNFGSNTPIAAFFKGIGDKAFGFMLPVLAGYIAYSISDRPAFVVGFVGGALAG
                     DGGSGFLGALLAGFIAGYLVEGLKKIFSVLPASLEGIKPVLLYPLLGTLLMGIIMTFL
                     VIPPVTAINNAMVGFLNGLGGTSKIFLGLVLGGMMAVDMGGPVNKAAYVFGVASLESG
                     QFEIMAAVMAGGMVPPLAIALATTFFKNRFTKEERDSGKVNYVMGLSFVTEGAIPFAA
                     GDPLHVIPACVGGSAVAGALSMLFNAALRAPHGGVFVIPVVTHPFAYILAIAVGALVG
                     MMLLALLKKPLNQEV"
     gene            5920..7446
                     /locus_tag="KOU88_001883"
     CDS             5920..7446
                     /locus_tag="KOU88_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK3211775.1"
                     /translation="MNESYWFLNSSPKEYNKLGENIKTDCLIVGGGITGLTTAYLLAK
                     EGKKVVLVEADKIGYGTSGRNTGKVTCQHDIFYSKIEKKYGLDKAKSYYNANNEALNL
                     VEQIIEENNIKCDFKRETSFVFTEKEDTIKNIKDEYRTCKKIGINCEYHETIENIPLD
                     IKGAISFTNQGQFNPKKYIDGLAKAAVNLGLKIYENTPVVDLEKGKICRVKTREDNII
                     EAENVIISSHSPWYDGLNFYFAKEYAERAYLMVAVLENKLADGMFISIDDPSITFRQY
                     NDGSENLLIFGGGDHKVGQGGTEKEIFDDLEHYGKEVFKVKDFKGKWSAQDNMSFDNV
                     PYIGYINKREDNIYVATGFSKWGITNGTAAGIIIKDLIINNNSDYKDTFNPSRLGSYF
                     SKDFIKENANVAINYVSGKLKIGSGDMPKNNGEGKIVNIDGKRYGVYKDDNGDFYIVD
                     TTCTHLGCELNFNSEEKTWDCPCHGSRFDYKGNILEGPALKPLKLYGHGDNDVNPKLL
                     "
     gene            7474..8031
                     /locus_tag="KOU88_001884"
     CDS             7474..8031
                     /locus_tag="KOU88_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211776.1"
                     /translation="MNKLLKPITILLYIVYILSAVFFVANKEYGSLGLVAISLVGTFI
                     LSFINKQTERLLSKELYIMLALFIMFSSLLGTCFNFYDINYYDDFLHLWSGIISCIVA
                     FSIIKYFYTQREISKMSKVFLVIFLFMFSMGVASLWEIGEFLMDTFVGTTTQAGGLED
                     TMIDMVDALIGTIITIPFIVKKSNI"
     gene            8553..9596
                     /locus_tag="KOU88_001885"
     CDS             8553..9596
                     /locus_tag="KOU88_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211777.1"
                     /translation="MLKKWFGIVKKRQKSESAKEEGEVILKNEKILSEEKLIDEEGVV
                     VNIDNEILTKVEVVNDDNEIEEKIIEEDWLISENTIKLDDKEAIINDKNIELCKKEVQ
                     VEGEKIDLNKFEGLDQNENYNLEKNVIEEKEVSECLTEEDLEYIKEIKIKRGKSIKAI
                     NLYTKEEWVFDTHIQCSKKLKVPLGYIRENLKYGYMDYFGDAINYLSEVLNIDEYCKS
                     EWSYLDNSKSPSEIFNILNNKIFSIRLSNEKRNEILTNDKIEALKMNYRFECIDEEYD
                     EYFKKYKSIIKRGGKKKVELVNKKGDILEIFKSLEECAIYLQKEKNEVIQMLKYGDTK
                     VGRNFIRYSLRSI"
     gene            9707..10849
                     /locus_tag="KOU88_001886"
     CDS             9707..10849
                     /locus_tag="KOU88_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK3211778.1"
                     /translation="MSEEKNPKENTLDESKNSDNVNSKKDDVSDEKNTDNKVKKREIK
                     LNNKTLKAIVAIVAVGAICLGGGYIFGKEAGRKLPATSKHYNSSEVVATIGDKKITGE
                     MLRKRMEPLFYLNAKTTMTDDEIRSYESNMIETMITSDILSSEAAKEKISITNDQLDA
                     QYNNLMSSIESAMGMTKEEFLKQFDLTEKYIKDDMKKELVASKYLNEKSKVTDKEAEN
                     YYNKNKSNYLQVRASHILIKTVDDKGKQVSSSKKAELKKEAEEILKKAQAGEDFATLA
                     KKYSEDSSAESGGDLGFFGKGQMVESFEKAAFALKKGEVSNKLVESDYGYHIIKKTDE
                     KYQPFEEVKSDLVSSLTSEKQNLLIQNLKEKYNVKITDKYQMKAKE"
     gene            11303..12694
                     /locus_tag="KOU88_001887"
     CDS             11303..12694
                     /locus_tag="KOU88_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBK3211779.1"
                     /translation="MSSTESVSKKSGHPKSFWLICMTILWERFSYYGLTALLVLFFTA
                     SVAQGGLGLSTQEATSMFGLFTGLIYLTPLVGGWLADKVLGQQKCISIGALLIAIGDF
                     VLFASSTSIAMVWVGLSIIILGNGFFKSSCSNIVGDIYPKTDVSRKDAAYSLFYMAVN
                     VGAFIAPIICGLLSDNVFAVRGASGDIVSYGYKMAFLICGIGMMLGMIIFTLLAPKLL
                     NEVGKYPVTKGNKGEKIEYGPLTKLEKNRIIAMVILFLFVVLFWTAYYQTQSSFMIYV
                     RDNVNRTLFGFEMPVAWLTSLNAILCVALCPVLATLWVKLSHTKRGDFSIPVKMGLGM
                     IIMGVGFIVMVFATLANGPDGMVKASILFIVLTYIFTTVGELFLSPIGLAMFNKLAPA
                     KYATLSMGAWYLTSFFASLLSGKIAGFTATLGFLQIFGGIATVLIIFGLILLGIRNVL
                     TRLMAMDLLTKEK"
     gene            12948..14741
                     /locus_tag="KOU88_001888"
     CDS             12948..14741
                     /locus_tag="KOU88_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK3211780.1"
                     /translation="MNIKDRLSGLRKFMEEKNIDAYMIPSSDNHQSEYVGDYFKSREF
                     ISGFNGSAGTVIVTKDEAGLWTDGRYFIQAESQLEGSTIKLFKMGQEGCPTTDEYLYK
                     NIPEGGTLGFDGRVISAREGATLAEKLSKKGIKIEYQYDLIDSIWPDRPALSDSKAFL
                     LDVKYCGESFSSKLARLREKMSEKGTSTHVITTLDDIAWLFNIRGGDVKYNPVVLSYA
                     VITLKEVYLFVDESKLNEEILNELAKENVQIKPYNDVYEFVKNIDKTEKVLLDGTKLS
                     YTIYNNIPCEVEKVDEFNPVMFFKAQKNEVELENIRNSHVKDGVAFTKFMYWLKKNVG
                     KMEITEISATQKLEDLRREQEGFFEPSFNTIAAYKEHAAMMHYSATPESNYKLEAEGL
                     FLVDSGGQYYDGTTDITRTTVLGPISDELKLHFTSVARGMINLSKAKFLHGCRGYNLD
                     ILSRSCMWNMGIDYQCGTGHGIGFVLNVHEAPNGFRWRVVPERFDSAVLEEGMVTTNE
                     PGIYIEGSHGIRTENEIVVRKAEKNFYGQFMEFEVVTLAPIDLDGIAPELMNKDEKDY
                     LNWYHKLVYDKISPFLTDEEREWLKVYTRAI"
     gene            complement(14822..16204)
                     /locus_tag="KOU88_001889"
     CDS             complement(14822..16204)
                     /locus_tag="KOU88_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBK3211781.1"
                     /translation="MSVLKTQEKLKQPRDLYFCCSIFTFVGLAYYGMKLVLLLFLAEQ
                     VSKGGLGLTPAESASMLASFLAWTYFSPVIGGWVSDRFLGPKNCIILGMLMVSIGYFL
                     GYIANSKMDINIMIFLSGLGIGFYKGNLHTMVGNLYTNDDPRKDGAFSITYMATNLGT
                     LFGPLICGLVANEWFAMKSGLSISMYGYRYVFLFSSITVLIGLFFFIFGNRKFYKPLN
                     NDPINGRESIRKSLEYKKMLASRPLTLIEKKRIIVILVLAFFTVFFWIAYNQASMSIA
                     LYTKEHINLTVGNFQIPTSWIDSYNGLLCVILGPISALVWVKLSQTKKGDLSVPKKMS
                     LGFILLAIAFLFMIVAVIQTGTDPNSIHKASVFWVVGFLTFQSIGEICFSPVGYGMVN
                     KLSPEKYISFLMGVWFLGKFAANKLSGYTQAIIDQLGMLQVFIVIPSFLLIFGIILLI
                     MNKKLVELSN"
     gene            16462..16809
                     /locus_tag="KOU88_001890"
     CDS             16462..16809
                     /locus_tag="KOU88_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBK3211782.1"
                     /translation="MIRKKSELQVEVKENLNGGIGKVKLENIIQNEELKGKGRLFKRV
                     ALPVGSSIGVHDHTTDFEVYYILKGKGKVFDNGEFVEVNEGDVVYTADGEKHSIENIG
                     EEDLEFVALVLYM"
     gene            16827..17861
                     /locus_tag="KOU88_001891"
     CDS             16827..17861
                     /locus_tag="KOU88_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211783.1"
                     /translation="MTGKIEEIKDKINRFCNSNLNQEYKDISFKILQNLLDNNKEIIH
                     SSRADIWSSAILNIVLEQNLLYNKKHPLHITKKEFSKQIGVSLNTINNKSSLIKDVCS
                     IDFLNQDTIAISNVEFWVKETNSKSKSVDLDLEKKKILYKRYIKLSQDANSDIESIRY
                     MEEAVNIGKSMITKEDKELGFWKGLSTRAYMIALESLARKLESINNLKESKKVLEYLI
                     EINPSDEQGIRYKLLNVLIRLNDRTSINKLFELYKEEKSATWMYSKALYYFKNKSMFL
                     ANDSIKVARSKNKYVGLYLLDWRNAFGREFVTEEEKAEAVYYYDENIVIWNEVKGSMD
                     WLLKKMLEFS"
     gene            complement(17910..18959)
                     /locus_tag="KOU88_001892"
     CDS             complement(17910..18959)
                     /locus_tag="KOU88_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3211784.1"
                     /translation="MEINYKKRNFKSFAKRKNIEISVQRYLIDALSYMALGLFSSLLI
                     GTIFNTLGDNFNISLFTEVISPLAKQVTGPAIAVAIAYGLQAPPLVLFSCALVGACGN
                     ELGGPVGAFVATLFAVEVGKLVSKETKIDILVTPAVTILIGVLVAELIGPAVSAFMTS
                     FGNIIMQATTMQPIIMGALVSALVGIALTLPISSAAICMMLSLGGLAGGAATVGCCCQ
                     MVGFAVMSFRENGVGGLVAQGLGTSMLQVPNIIKNWKIWIPPTVASILLGPLSTTIFK
                     MENIPIGSGMGTCGLVGQFGTVTAMQSAGKGGISMWVGILLLNFILPAIVTLLISEFM
                     RKKGLIKPEDLKLDV"
     gene            19234..20769
                     /locus_tag="KOU88_001893"
     CDS             19234..20769
                     /locus_tag="KOU88_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211785.1"
                     /translation="MIFVKNKKYRKIAIIISIPILLVAQYYLFKFGILRPMVKGVEIE
                     IVDGEYVKDIDKYVVKLNETVTLSTGEYIKVPSYAKNPNIWFNVLDNSGTLKIDGNKM
                     TALKVGYSSVGIMKNSRVLKKATIKVVDPEVESLDMEINGDLKHVGDSATIESTIEVD
                     YDKFKKSYKPVYKSSNENILKIKGNKVSAVGVGKATIYAKCGNKEIERTFRIQARVAE
                     INMDDIKIEVDQNEKLKPDIITSPPGLEPPKIYYELVDSKLPVERAISLSSNGNVVGL
                     REGKDRVRITCGDKSKVITVTVVKETITNDYIQNLVGSHKIVNNKVIIKLEWDYMKDV
                     FDYDIYLKDKLSGESFKKIKSITINESDLGKSNKVYATIEVDMKGNQNIDFDIYVIGK
                     KDSDTTKPSNVINITNGNGNSNNDNNIKDMRVENISANVDRDNNVIRVNWSSISHKDC
                     TYSIYVKNNTNGDGEFTLYQSDIQGNEHTISIPEGDLNLDIYVVANYNGNSSQNSDVI
                     NVR"
     gene            complement(20954..21640)
                     /locus_tag="KOU88_001894"
     CDS             complement(20954..21640)
                     /locus_tag="KOU88_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="HBK3211786.1"
                     /translation="MKTIGLIGGMSWESTITYYQVINTVIKERLGGLHSSKCILYSVD
                     FQEIEECQSSGNWEKSAKILADAAIKLQEAGADFIVICTNTMHKVSDKIQESIHIPLL
                     HIADVTATVLREKEIKKVALLGTKYTMEQDFYKNVIINNGIEVLIPNEEDRIIVNDTI
                     FNELCLGIISESSKKAFLSIIDKLGKQGAEAVILGCTEIGLLIKQNDTSIPLFDTTVI
                     HAIEAALSSI"
     gene            21765..23147
                     /locus_tag="KOU88_001895"
     CDS             21765..23147
                     /locus_tag="KOU88_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK3211787.1"
                     /translation="MPINSFENYPMTWKPKLDNRKPPIYKTLAMLLEEDIKRGNLNPG
                     DKLPPQRELADFLDLNLSTITRAFKLCEEKGLICAKVGKGTFISSDVNVSNTLLYQTE
                     SKDIIELGTVHPPYEQNTYIIDFIKNVLKQPEMDRFLQYMSPSGTYMQKKSIAKWIER
                     NNVYTSEENILLSTGGQNAICATLLGLFKAGDRIATDSLSFSGIKSIAKMIGIQLVPI
                     PQENNEISIEYLESYCKNENIKGIYLIPDYHNPTTHTMSDLSRKKIAKIAKQYNIIII
                     EDAINSIFRDGIQTPIFSLASDNTIYIFSTSKFLCAGLRVAFVVAPKRYIENLENALY
                     NMNLMVSPFTAEIVHRLLYSPIIDKIIEEKRDAIIERNEVADKVLSDYNLIGDKNCSF
                     RWLLLPDELDGKSFEISAKNLGVQVYCAERFSVGNSTVPKAVRICVTAPKDVEELEKG
                     LNIIKSLLKS"
     gene            23549..24817
                     /gene="eam"
                     /locus_tag="KOU88_001896"
     CDS             23549..24817
                     /gene="eam"
                     /locus_tag="KOU88_001896"
                     /EC_number="5.4.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 2,3-aminomutase"
                     /protein_id="HBK3211788.1"
                     /translation="MNEQTRISLERAAELKSKIDDYIQARKTINRGLEKEEEINKRKQ
                     KILSILNGTEEDWNNYKWQLSNRITDVDTLSKIITLTKKEKEYIKEVGTQFRWAISPY
                     YLSLIDPEDTCDPIKLLSIPTHIELEDEQEDLDPMGEEYTNPAGCITRRYPDRLIINV
                     TNECAMYCRHCQRRRNIGQQDSHKSKAIIQESIDYIRENEEIRDVLVTGGDALTLKDD
                     YLEWILSQLKEIPHVDYVRLGTRTLVTMPQRITDEFCNMLKKYHPVYINTHFNHPMEI
                     TKESKEACEKLANAGVPLGNQAVLLNGINNDKFVMRCLNQELLKIRVKPYYIFQSKHV
                     KGTKHFNTSVDDGLEIMEYLRGYTSGMAIPTYIVNAPKGGGKTPLLPQYLVSKGTDYV
                     MLRTWEGKVIKMEDEPAVDIKKLIKEQAQD"
     gene            complement(24910..25266)
                     /locus_tag="KOU88_001897"
     CDS             complement(24910..25266)
                     /locus_tag="KOU88_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211789.1"
                     /translation="MKKALISLLVLSCLLLTAPVNESSYADSQKNVPVSQNTKLTQEQ
                     AKELLVKYNNEVDYIYQGNASDFEALKAKNLNGYVFLPDADGDIGYFVNENTFEIYYF
                     HPSGYLELVNQQQNNK"
     gene            complement(25417..26511)
                     /locus_tag="KOU88_001898"
     CDS             complement(25417..26511)
                     /locus_tag="KOU88_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK3211790.1"
                     /translation="MQDKKIYLNIVLTVVVSYILIKVIDNYKYFFGVISLLMSLLTPF
                     IIAFVLAYIFNPLVKFLESKLNFKRIYSLLLTYGVLIVILISFILFTVPSIVNSLADL
                     VAQIPTYIDKTEQFLFDLGKSLQSVDPNTLKEYGDKIMSVMPKFSNLLIGSLGGIFST
                     TFSVGKFIVQFLLGFIICFYILLEKEKFLLFTKKVVYISLGKKYGDFIIELCQSLNLN
                     IGKYFTGKILDSFIVGVLSGIGLYFLKSEYALLFGTLMGVMNMVPYFGPVIGMAPVVI
                     INLFSNPTIALTSLIYLIIIQQVEVTFIEPKIVGGQLGLSPFFTILAVTVGGGFFGIP
                     GMILSAPVMGVIKIYFCEFVNRRHDKIQME"
     gene            26975..27796
                     /locus_tag="KOU88_001899"
     CDS             26975..27796
                     /locus_tag="KOU88_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBK3211791.1"
                     /translation="MIKKEISNFRGSSDYVVSPELMASVNVAIALEKPLLIKGEPGTG
                     KTMLAQAISNELKKDLVIWNIKSTTKAQEGLYVYDTVQRLYDSQFGGEGVDDISKYIK
                     YGKLGEAFSSNQQVILLIDEIDKADLEFPNDLLWELDKMEFYINETKETVRAKQRPIV
                     IITSNAEKELPDAFLRRCIFHYIEFPDRDMMEEIVKVHFDKVEEHLLEQVMTTFYWIR
                     SLKDIQKKPSTSELIDWIQALTLSGMPIEKIEKEVPFAGILLKNNEDIESMQRHL"
     gene            27817..29013
                     /locus_tag="KOU88_001900"
     CDS             27817..29013
                     /locus_tag="KOU88_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBK3211792.1"
                     /translation="MFIEFFYLLRSRGLNVSLNEWMTLIEALDKGLCYSNFSNFYYLC
                     RMILIKSESDFDKFDAVFLEYFKGIEHQEEIPEEIMNWLKKPDIDLEEFERLEQNPNI
                     NLDKLRAKLEERIKEQDSPHNGGNYWIGTGGTSELGHSGKGQTGIRIGGNSTYGRAVL
                     EVAGERKYRDFRDDEVLNMRQFQVALKRLRQFSTRIDAPKTELDLDKTIEETCNNAGY
                     LKLFFEKPRKNTVKLLLLMDSGGSMRGYSTLCNTLFQSVSKSNHFKDVKIYYFHNCIY
                     DRLFTTPECWLSKSINTEWILKNIDKNYKVIIVGDASMSPSELLHIGGNYRGPYNYTP
                     GIEWLKRFKRKYSKIVWMNPELRDGWDSISYWYQTQRMIQSEFNMFPLTVKGLEKALK
                     NLMVSR"
     gene            29180..32578
                     /locus_tag="KOU88_001901"
     CDS             29180..32578
                     /locus_tag="KOU88_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HBK3211793.1"
                     /translation="MIIINYELIVKYNGDILRLEEELGVSVEILNSSYAIITSSNEED
                     VNILLTYPEIEFIEKPFILQTQDVQSFSSTGITGFKNRTGLTGKGTIIGIIDSGIDYT
                     LPVFRDSDGRSKILYYWDQSIQGNPPEGFREGTLYTNEDINNAIDGSMYIPISTTSLH
                     GTHVAGICATIASDARIIVVRVGNIQTDIFSRSTEFMRAIKFILDRALELRMPVTLNI
                     SYGSNEGSHRGTSLFEQYIDDMCLFWKNNIVVAAGNNADKGGHKRIRLQNNITEEVEF
                     IVGEGERILNINIWPDFVDDFSVHLVNPSNNQTQAISLTSGEIRNTLGETRITGYFYP
                     IAPYSLTRRVTLQLSSNTQITPGLWKIVFEPIDIVTGNVNIYLPTSEGLNRNTRFLIP
                     TQELTVTVPGTASRVITVGSFNSRTDIVSIFSGEGDTQLGVFKPDLLAPGEDIVSFLP
                     GGTSGALTGTSMATPHVTGVCSLFMEWGIVNGNDLFLYSQKLRALLLKGARRLSNQSY
                     PNNSSGFGFLNLSDIDLYTLSNINQDLETEDIGYRSINKSFKDEENSYKFIDGYNMQI
                     HNDLENEIYISKNASRQSGILSGIDIVHTPEFEEELAGLGMSQRFFKISDSLGVLSIN
                     NTDYNSIQRVLQLPSIIRTVSTTKMTLLGEINRGTFGGVVATEEMGVNFFKNNPNINI
                     TGRGTLISIADTGIDYLHPDFIYPDGTSKIVYLWDQTKEGTPPDGFYIGTEYTREDIN
                     RAIAENDPSLSQDEVGQGTMLSGICAGLGNVNSEYAGIAEDSELIIIKLGKIDDFYNS
                     AMLFAASQYAYKKAFELGRPLVINMSLGTSSLAGLTNRSNSEKAFFTRGLCITAGAGN
                     EGNTQTHTSGIIPYVGGSVEVELELNEDEEELSLELWLNRPDKADVIIVSPTGEESKS
                     VGISNYNKVTGLFDLEGTEYSITYIYPTTFSGQQFTNVTLKNAKRGVWKIRLVGVYII
                     TGRYNLYLTNRELLKSGTRFREVDPFYTINYPAIQDDLITIGAYNTINGSLWQSSSRG
                     PTIEDRLKPDIVAPGVNIIAAYPGNTYATITGTAAASAHAAGAAAMYFQYTFVDGRYP
                     NQAYVQKIKTFMQAGARKDSNTVYPNTNSGYGLLDVRGMFDVLR"
     gene            32588..34261
                     /locus_tag="KOU88_001902"
     CDS             32588..34261
                     /locus_tag="KOU88_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBK3211794.1"
                     /translation="MEKSYCIIYQGDIESALQENGINRYMVLNSQLAVIYVPLDFDET
                     ILNNIIQVAWWEESEPMSSLIEITNNVNNGETITTAAETDYIYENPYNDITGRGILLA
                     VIDSGIDYLHPDFINDDGTSKVLYLWDQEANTNPPPEGFIFGSEFTRSELNIAINRND
                     GSLSQDNIGTGTLVSGILVGNGRINSQYRGITTESDLIVVKLKSYTDTYYAGRINYSV
                     SDFLAAITYVTNIARTENKPLIINLTIGVKSSAVATTSILDTFNILSSAGVVVVSGAG
                     NQGNTDIHYSGRFSSVGEVQDVIIQDGDDYALDITLNTNGPDKVGAQIISPSGEVSHD
                     IRYSPDFYIYRGKFNLENTTYAMRFIYPYITSGKENLEIRLRDIKPGVWILRLTSELI
                     INGEYDIYLPNKNLIAPDTRFLEPDSVATITMYAASDDVITVGTFNNKTDSMWIGSSK
                     GPIRGRGIKPDIVASGVDIISTYKNGTYNTGTGTGVSSSIVTGVLALLMEYLEKQDNV
                     PRLSLFTQVLKTYLILGATKLEIYTYPNVSQGYGILNLKNTIQQIANTL"
     gene            34534..34728
                     /locus_tag="KOU88_001903"
     CDS             34534..34728
                     /locus_tag="KOU88_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3787 domain-containing protein"
                     /protein_id="HBK3211795.1"
                     /translation="MESKKARALKGKDNKRLKSSLLVGNESTAAWADVEKLKPHSKVS
                     IPSIKGVEEAKDWVDNGSKL"
     misc_binding    34897..35130
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            35207..36604
                     /gene="asnS"
                     /locus_tag="KOU88_001904"
     CDS             35207..36604
                     /gene="asnS"
                     /locus_tag="KOU88_001904"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBK3211796.1"
                     /translation="MQKEFITVKELYREKEQYIGKTVKVAGWIRTSRVSKNFGFIELN
                     DGSFFKNMQIVFDEKVENFKEVGKLAISSSILVEGELVSTEGAKQPVEIHAKSIVVEG
                     ESDSSYPLQKKRHTLEYLRTIAHLRPRSNTFSAVFRVRSIAAYAIHKFFQERNFVYAH
                     SPIITGSDCEGAGEMFRITTMDLNDIPKTEDGKIDYTQDFFGKEANLTVSGQLNAEIM
                     ALSFRNVYTFGPTFRAENSYTGRHASEFWMIEPEIVFADLEDNMELAEDMIKYVISYV
                     LENAPEEMEFFNSFIDKGLLERLNKIVNSEFIRITYTKAVELLIESGHEFEYPVEWGC
                     DLQTEHERYITEQIYNCPVFVTDYPKDIKAFYMRMNEDGKTVRAMDLLVPGVGEIVGG
                     SQREEREDVLLDRINEMGLREEDYWWYLELRKFGTATHSGFGLGFERIIMYMTGMSNI
                     RDVIPFPRTPKNAEF"
     gene            complement(36777..37952)
                     /locus_tag="KOU88_001905"
     CDS             complement(36777..37952)
                     /locus_tag="KOU88_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3211797.1"
                     /translation="MNLEKIKKFFGFPLDKKHKDNVEKELCNYLYHTGKIICIIIVIS
                     QIIMMISISAREGGPFVTPRRQWYFYMYVTLFCVSSVFMFVFSYLWNKKKDCCTFYIN
                     LWIIYVTFFCLWGCVITLLDQLGGNDLSVFSYIMLAAAAFSVLKFGESVIVFGGCFLF
                     LNLFLPGIQTIPGNEFSNIVNTFFITSLAIFVSTMLYRNRVFTYYDKLLISQQYEEIS
                     HINNLLNDKVMTDDLTKMNNRRYLEDILQKKLISHANQEPITGMMIDIDYFKQFNDNY
                     GHQKGDYCLQNIAKVILDFTSSENEHAIRYGGEEFFICIFNCNEADAKLKSECLRKII
                     ESCNFERDDVPLKCVTVSIGVYTKKIGKTITLNEFISNCDKALYTAKEQGRNCVAFY"
     gene            38371..39735
                     /locus_tag="KOU88_001906"
     CDS             38371..39735
                     /locus_tag="KOU88_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK3211798.1"
                     /translation="MGEKKINNMNYSHNNYSKKTGEPTRKIKNSHITLKSKEEKICSS
                     CNKENNTKDNYCKFCGNELYEIASLRPLETKLDLKSKIKELSYHANKRGVFLTTFTTI
                     FILFIIALIFKAIITIQFNDISYLINPAHIILALNLGQISVSMSTMMGSGFINANIGL
                     LILLIIPILVLLISNLIFMRKRCRDSKTVLANSLGVGIFYGLVLAILSIFTNVKTSSH
                     SMLEYGYALEYSYEFFSVLLNGFVLGFICTYITTYKKSYEKENMYLSLFSNSIRTFIL
                     GYVLVLVILLVLTISDSSYLNELDMSSYSNGLNLFTILPQIASYMWAFANGISVTIIN
                     STVSMFTLSSSSLFGDTKLMFYAMGALSMLILLLNGYKLRFKYNTDSIRPIIVFSIYY
                     AFLMGILALFSTFILDSNINFFNTTNYGTTLIMQFKVLQAIVISFVYSFVISLIGYKL
                     NSAD"
     gene            39757..40248
                     /locus_tag="KOU88_001907"
     CDS             39757..40248
                     /locus_tag="KOU88_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK3211799.1"
                     /translation="MEGNTNNKVDDKFSKVKKKFGSGKFKVELYKEKSKLNREIDDIQ
                     EKKAKIFLEMGILTYQKIREDSINDNSFDKFCDELLELDKLIYEKNMEINEMEMAESN
                     VTCECGYVGNVNDKYCAECGKKFELENECDDFIICGYCESEIDTEAEFCPCCGRKIIM
                     DLE"
     gene            40521..41192
                     /locus_tag="KOU88_001908"
     CDS             40521..41192
                     /locus_tag="KOU88_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBK3211800.1"
                     /translation="MLDKVKGRLIVSCQALEDEPLHSPFIMGRMAKAAMEGGAVGIRA
                     QGVEDIIEIKKVTGLPVIGIIKRNYEDSDIYITPTKKEVDELLTTGCEMIALDATNRV
                     RPNNEDLKELIKYIKENGVLVMADISNYDEAIKAQEYGVDCVSTTLSGYTPYTKTLEG
                     PDFVLMERLVKDLEIPVIAEGKVNTPQDLKKVFELGVHSSVVGSAITRPQLITEKFVK
                     AIEIN"
     gene            41277..42143
                     /locus_tag="KOU88_001909"
     CDS             41277..42143
                     /locus_tag="KOU88_001909"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBK3211801.1"
                     /translation="MKGIYSALLVSFDKEGNINEKGLRQIIRHNIDVCKVDGLYVGGS
                     TGENFMLSTDEKKRIFEIAKDEVKEEIKLIAQVGSVNLKEAVELAKFTTDLGYDAISA
                     VTPFYYKFDFEEIKHYYNTIINSVDNRLIIYSIPFLTGVDMSLDQFGELFENEKIIGV
                     KFTAADFYLLERMRKTFPNKLIFAGFDEMMLPATVLGVDGAIGSTFNVNGVRARQIFE
                     LTKNEKISEALEVQHVTNDLITDILGNGLYQTIKLLLEEQGVEAGYCRQPMKEATDEM
                     KSRAKEIYRKYF"
     gene            42176..43678
                     /locus_tag="KOU88_001910"
     CDS             42176..43678
                     /locus_tag="KOU88_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBK3211802.1"
                     /translation="MVGFTWIDFAILVVYLLAVLFAGLLFSKKEMKGKEFFKGDGTIP
                     WWVTSVSIFATLLSPISFLSLAGNSYGGTWILWFAQLGMFIAIPLTIKFFLPLYSRLE
                     IDTAYEYLEMRYESKGLRVLGALMFIIYQIGRMSIIMYLPSIVLAGLTGIPVNVLIIV
                     MGVIAIIYSYTGGLKAVLWTDFIQGMVLIVGVTGTLFYLIASINGGFGTVMDTLTTGH
                     KFLASNEVMFDKNILSTSAFIIFVGAGLNTFSSYVSSQDIVQRFTTTTDIKQLNKMTY
                     GNGVLSMGLATVFYLIGTCLFIYYTQNPDLAQTVQQDQVFASYIAYELPVGITGILLA
                     AIYAASQSTLSTGLNSVATSWTLDIQTIITKDISMEKQTKIAQYISLGVGILSIAVAI
                     VLANGEIKSAYEWFNSFMGLVLGVLAGIFVLGAFCKKATKMGAYVGFIVSAILVVYLK
                     YRMPEVTSWAYSLITITTSVVVGTIVSAIEAKVKAKVSLPKAETTVYYEK"
     gene            43808..44260
                     /locus_tag="KOU88_001911"
     CDS             43808..44260
                     /locus_tag="KOU88_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBK3211803.1"
                     /translation="MIFGNINHSKTYSTLHEDLLRCFEYAKDNSLIDYEKGTYTIDGD
                     DIFVNIVEYKTCEKEDRFWEAHKKYIDVHLMLDGCERIDINFIENLEQKIYEEKGDFL
                     PLDGKNNGYMELRKGDFLVCYPEDAHMTGIKVLEKENIKKAIFKVLVR"
     gene            44420..45223
                     /locus_tag="KOU88_001912"
     CDS             44420..45223
                     /locus_tag="KOU88_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211804.1"
                     /translation="MENIDVFLLIGQSNARGLGNPKESIIPNENCFEYLSTDEIINMR
                     CELETSEGDGTIAPAFSNEWNKLTGNKVCFIHNAKDGSRIKNWNHDNNWFLNDTIEKF
                     NTGCTTLSKHYNIENKYVIWIQGESDAKYGSDVLYYKESLKKIAYRLKEECMIDKMFV
                     SLTGYWLGEDEYFIRTRRIAAAQESACSECDILCVGSKIAMQFHDRGLTIDDVHYTQE
                     GLNMLGEDLCKNIYKYHITKEKSVLSDTIDLSEARKYICELEKISKRFV"
     gene            45281..46168
                     /locus_tag="KOU88_001913"
     CDS             45281..46168
                     /locus_tag="KOU88_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK3211805.1"
                     /translation="MKNYVCIDVGGTSIKYGFIREDGFIIDKSSLDTEAKEKGGEGIL
                     AKIKDIVKKYIEENEISGICISTAGMVDPVEGKILFALEELIPNYKGMQLKKEVEKEF
                     NIKCEVENDVNCAGLGEMWLGAGKDATSSICLTIGTGIGGCIIINNKLINGFSNSAGE
                     VGYMNVNGSSFQELASTSSLIKKVAKIKNLNENDLNGKIIFDLAKNNDEDCLKELDNM
                     IKSLAVGIANICYVINPEVVILGGGIMAQEKFLKPKIDKALKEVLIERVYKNTNIEFA
                     KRQNDAGMLGALYNFLNKI"
     gene            46187..47035
                     /locus_tag="KOU88_001914"
     CDS             46187..47035
                     /locus_tag="KOU88_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3211806.1"
                     /translation="MSILEQLESPTFKVTKSDKLLIAYIKENIDDVFYKPISQIAKES
                     NIGEATITRFVKKMNFNGLQDFKVTLAQEISTINKKNIINKNIQNDEPALDTAKKLLS
                     SNVTTLENTVEIINSKDVHDCARLIINAKKVYFIGIGYSGIIAQDSNYKFMRIGLNCV
                     SFDSSHTMIMMSSIMEEGDLIIAISHSGETEEIIKTVKLARANNAKIISITENKNSEL
                     KDISDVHLSYVSGETVLETGSISSKLAQFFIIDLVYTQVVKELSNEAIERKIKTTNAI
                     KLFKNE"
     gene            47098..47787
                     /locus_tag="KOU88_001915"
     CDS             47098..47787
                     /locus_tag="KOU88_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK3211807.1"
                     /translation="MSKLKDYNIDKVIIFNNLSTKTKNQLKEKVKLKRLQKKEILFYE
                     KDSLDSVYILLEGKVSIFKISENGERKVIFILNSGEVINDITLDASKNSTVGCEAFEN
                     SIVAYYSIEEFLEIMQNDFQLTKDIISYMERRIRRLYRQLKNSISIKVDKKLAAKLYR
                     LSREFGVCCGEWTLLNVNITVTYLADMLGCKRETVSRMIKVLQKEELIKIDNKGFYVK
                     ETELSRYFKNN"
     gene            48178..49185
                     /gene="asrA"
                     /locus_tag="KOU88_001916"
     CDS             48178..49185
                     /gene="asrA"
                     /locus_tag="KOU88_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrA"
                     /protein_id="HBK3211808.1"
                     /translation="MKLKLDSSKFNEGLNYLKKDYKIFAPVLIPFKGTFSDTDVIRYK
                     EVNAFEEMEFAKKANFSPKEVVLPINQVLFYFTEKEFKESDLDNKKILIFLRACDING
                     IKRLDEIYLNNGEEKDYFYKNIRDKVKFALVGCKESFRNCFCVSMDSNKTDNYSIGLN
                     IEGDTLYLDIKDSEFEVFNGEATEFNVDYVTDNLISVDVPENIDSNEMIGNSIWDEYD
                     TRCIGCGRCNFVCPTCSCFTMQDIFYKENENVGERRRVWASCQVDGYTDIAGGNSFRK
                     KQGERMRFKTMHKIHDFKKRFGYHMCVGCGRCDDACPQYISFSKCIEKINDLVISKEE
                     V"
     gene            49186..49977
                     /gene="asrB"
                     /locus_tag="KOU88_001917"
     CDS             49186..49977
                     /gene="asrB"
                     /locus_tag="KOU88_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfite reductase subunit AsrB"
                     /protein_id="HBK3211809.1"
                     /translation="MNPYIPVSAKILDIVKHTDKEWTFRVNCNTKGVLPGKFYEISIP
                     KYGESPISVSGYGEDYIDFTIRNVGKVTSELFNYKEGDSFFIRGPYGNGFDVSLYEGR
                     EIVVVAGGSALAPVRGIVEYFYNNKEKCEKFKLIVGFKSPKDILFADDLKRWSKKLDI
                     LVTVDGAEEGYSGNVGLVTKYIPELDMKDINNTSIVVVGPPMMMKFTVEEFLKRDLDE
                     KNIWVSYERKMCCGIGKCGHCKMDDTYICLDGPVFDYSYAKNLID"
     gene            49990..50961
                     /gene="asrC"
                     /locus_tag="KOU88_001918"
     CDS             49990..50961
                     /gene="asrC"
                     /locus_tag="KOU88_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite reductase subunit C"
                     /protein_id="HBK3211810.1"
                     /translation="MIRDLNTKKVMKNAYRITKTKYETSLRVRVPGGLIDPESLAVVS
                     KIASEYGNGQVHITTRQGFEILGINMEDMEEINKIIQPVIEKMNINQSEKNAGYPAAG
                     TRNIAACIGNKVCPKAQYNTTEFAKRIEKAIFPNDLHFKVALTGCPNDCIKARMNDFG
                     IIGMALPIYEKDRCVNCGACVKKCSKISVGALKTENNKVVRDKDKCIGCGECVLNCPT
                     NAWTRDEKKYYRLAIMGRTGKKNPRLAEDFLLWVDEDSIIKIILNTYRYVEKYIDKDA
                     PGGKEHIGYIIDRTGFMEFKKWALEGVELPEITKMYENIYWSGIKYL"
     gene            51018..51794
                     /locus_tag="KOU88_001919"
     CDS             51018..51794
                     /locus_tag="KOU88_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBK3211811.1"
                     /translation="MHKETLDKLTNAAINKINLLNTSKVKYLVSSAFAGLYVGIGILL
                     IFTIGGLLTDAGSPMTKIVMGLSFAIALSLVIMTGTELFTGNNMVMSAGMLNKGVSIK
                     DTSKIWAYSWVGNLIGALVLGIIFVGTGLIDKGPVAEFFANTAASKASMPFTALFFRG
                     ILCNILVCVSVLCSFRTNSDTAKIIMIFLCLFAFITSGFEHSVANMTIYSVSLFSPTI
                     NTVTIGGAIYNLVAVTLGNIVGGALFMGLGTYILGKEKLN"
     gene            52065..54083
                     /locus_tag="KOU88_001920"
     CDS             52065..54083
                     /locus_tag="KOU88_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK3211812.1"
                     /translation="MTKKLVISKTKLFIFIIAFISIFIYLFGSKNTLIGVGIVTAMLT
                     LLERDLTISPIKNLLKYLAINIILGILSFFAVQNMYLGVLLNFIALFIIGYVFSYDLK
                     RAVYVPFGLMYIFMVSIPVGKSEFPMRLSALAVGAVIIMIAQFVMNRNRMKNVGDKEL
                     ISICDELLEKISLLKNTINDDSSIIKSSMRKIDSCNYRINSISKNLKMVIFDNRKDDF
                     YISIRGIDIMNILFSLERISLILERYKKDSKEFEDEDIKNILEESSINSKSDVLVVAT
                     KEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNINLKEIYSVLENLYEFLVDYKKV
                     KSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFSYAVKIALATAVAGFIMDYFHLR
                     DGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAVIFIVLFSIIKDSTLRSLIVLLA
                     GYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTISRISYVALGAIIALIVNKFILP
                     YDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVYYIKNLLLIPSLIEDRLMLINAI
                     YKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDEDVEKILRDTNYISNYNVDKYDEG
                     RSVILESIINTKSLGDKIICLNLLQTLNGVKEMYRISNITKVSIKEAA"
     gene            54298..55155
                     /locus_tag="KOU88_001921"
     CDS             54298..55155
                     /locus_tag="KOU88_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3211813.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            55252..56121
                     /locus_tag="KOU88_001922"
     CDS             55252..56121
                     /locus_tag="KOU88_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3211814.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(56491..57123)
                     /locus_tag="KOU88_001923"
     CDS             complement(56491..57123)
                     /locus_tag="KOU88_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBK3211815.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(57195..57548)
                     /locus_tag="KOU88_001924"
     CDS             complement(57195..57548)
                     /locus_tag="KOU88_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBK3211816.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            complement(57626..57829)
                     /locus_tag="KOU88_001925"
     CDS             complement(57626..57829)
                     /locus_tag="KOU88_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBK3211817.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            57958..58167
                     /locus_tag="KOU88_001926"
     CDS             57958..58167
                     /locus_tag="KOU88_001926"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211818.1"
                     /translation="MVQVTAKQPFQRLFTNHYIVALLIKVMAYSICWLSVSQTYLSTL
                     FSCQRTVGIDLPIKNHNSLWAFIDK"
     gene            complement(58219..58449)
                     /locus_tag="KOU88_001927"
     CDS             complement(58219..58449)
                     /locus_tag="KOU88_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3211819.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(58451..58858)
                     /locus_tag="KOU88_001928"
     CDS             complement(58451..58858)
                     /locus_tag="KOU88_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3211820.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            complement(59218..59667)
                     /locus_tag="KOU88_001929"
                     /pseudo
     CDS             complement(59218..59667)
                     /locus_tag="KOU88_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            complement(59681..60607)
                     /locus_tag="KOU88_001930"
     CDS             complement(59681..60607)
                     /locus_tag="KOU88_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211821.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            complement(60732..61514)
                     /locus_tag="KOU88_001931"
     CDS             complement(60732..61514)
                     /locus_tag="KOU88_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBK3211822.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            complement(61670..62290)
                     /locus_tag="KOU88_001932"
     CDS             complement(61670..62290)
                     /locus_tag="KOU88_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK3211823.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            complement(62378..63076)
                     /locus_tag="KOU88_001933"
     CDS             complement(62378..63076)
                     /locus_tag="KOU88_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3211824.1"
                     /translation="MYKLSYVVRVSTKNLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKKDSESLAIDILTFLTGISSRDSD
                     KFLQKNDNWKIIME"
     gene            63177..63992
                     /locus_tag="KOU88_001934"
                     /pseudo
     CDS             63177..63992
                     /locus_tag="KOU88_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            64664..65431
                     /locus_tag="KOU88_001935"
     CDS             64664..65431
                     /locus_tag="KOU88_001935"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBK3211825.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(65759..66436)
                     /locus_tag="KOU88_001936"
     CDS             complement(65759..66436)
                     /locus_tag="KOU88_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211826.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(66586..66903)
                     /locus_tag="KOU88_001937"
     CDS             complement(66586..66903)
                     /locus_tag="KOU88_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211827.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            complement(66925..67263)
                     /locus_tag="KOU88_001938"
     CDS             complement(66925..67263)
                     /locus_tag="KOU88_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211828.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
BASE COUNT        26239 a         7646 c        11386 g        22417 t
ORIGIN      
        1 gaggaagttt tggttctatt gaagatatga ttgatggatt gtttgaaaaa gatggtgcat
       61 ttaatatgtt aaataatagt tactataatt tgcctataaa taatccgtca tataaaaaat
      121 tagtagaact tataagagac tattctaatt taccaatatt aaatcattgt acagctggta
      181 aggatagaac tggtgtgggg agtgctataa ttcttatgat tttaggggta tcgagagaga
      241 atataatgaa agattatcta aaaagtaatg attttgcaga taaagagata gaaagattta
      301 tagaatataa gcctaaattt aaggacattc caaaagaaaa tttgaaatat atatttggtg
      361 taaatgaaga gtatatgaaa actgcattta gaagaattga tgaagaatac attagtgtag
      421 aagcatattt atatggagaa tttaatttaa ataaagaaga aataagaaaa ttaagaaatc
      481 aatatctaga gtaaaaggtg agtttatgag tttaaatata acagcaagac agataaatat
      541 aataaaaata ttgttaaatt caaaagatac aattagtggt attgccttaa gtcaagagat
      601 aggatgttct tcaaaaacta tacaaaatga aataaaggat attaataaac aacttagaaa
      661 tggtaaaatt ttgtcaataa gaggagttgg ttataaacta gaaggaagtt ttgatgaggt
      721 aaatctaaat agcaatctct atgatgatgt agatagagta gaatatataa tcagaaaaat
      781 attaacctta agtaatgaag aaaaaaatac tataaaactt gaagatttag ccgattctat
      841 gtatgtaagt gtttcaacag taaaaaatga tttaaaagaa gtaaaaagaa tattggaaaa
      901 gtattcaata tcagttaaat ctaagcataa acaaggtata tgtgttttgg aaagtgaaga
      961 taagatatta aattgtatag ttgacttaag caataagaga gataatcaat tgagtttaaa
     1021 tgatttttta aatgatgata taaaggaaag aaaactatta ataaaaaaat tattattaga
     1081 catattaaat gaaaatggat tagtattaac tgatatagaa tttaagagtg tgttaaataa
     1141 tatattagtt atgttaagca gacataagta taatgaaaaa gaatttatag agaattatat
     1201 agaaaattat aggagcaaaa gaagctcaat tttagaaaat gaacaaaaca aagaaattat
     1261 aataaattca ataaaaacat tttgtaaaaa tttaaaatta gctacatcaa tagatataag
     1321 taatgataag gtatttgaag agtttttata taagcatatt agtagtttat gtaaaaaaat
     1381 aaagttaggt ataaatcaat cacctataat ggctcaagat ataaaaataa aatatccatt
     1441 tgcttttgaa ctagctaata tagctaaaaa gacaatagaa aaagatttga agatagaaat
     1501 taatgaagat gaagttgcaa acatagccct acatatagga ggagcagttg aaagagcatc
     1561 ttataataat aaagataagg ttttcaaaac tataatagtt tgtacttcag gcataggcac
     1621 atcaatgtta ataaaagcta aattagagaa tatatttaag gaaaaattag aaatactaaa
     1681 gattattcct tcatacttag ttgaatatat aaaagttata gatgttgatt ttgtaatatc
     1741 tactgttcct attgaagtag gagatgtgcc agtaataaat atatctccaa ttttaagtga
     1801 gaaagaaatt agattaattg aaaaatatat agaaacagga aatatatacc tagatttaga
     1861 tataaaaagc ctgtttgata gtgaattgtt ttttactgat ttggtgttta aaaggaaaga
     1921 agaagttata gattttatgg caagtaaact tgtacaaaag ggctatatag atgaggatat
     1981 gaaaaaatct tactttgaga gagaaaaaat agcaacaaca gaaataggga atatggtaac
     2041 tataccacat ggagctattg gaaaaatttt tgataataaa atagcaattg gtatattaaa
     2101 gaagcctatt tcttgggaaa tatcagatgt tcgtttaata ataatgttag cccttgataa
     2161 agataaaata ttagattatg aagtaatatt ttcaaaaata tataaaagag tagattctat
     2221 agcaaaagtt ataagtatat gtgaaaatag tagttttgaa aaatttgtaa atttatttaa
     2281 ttagatgggt agtattgtat atacacctgt aaatttggat aatataaaac taaataagat
     2341 aaaaacgata aatttctctt ttaattaaga gaaatttttt gactttcaag gatattaata
     2401 taaagttaag atataaacat aaagcaaata aataaaaaag aggtggcaat atgatttata
     2461 cagtgacatt aaatccatca atagattata tagttaagct agatgagcta aagacaggaa
     2521 gtacaaatcg tgtaaaagaa gaatacgttt atccaggagg aaaaggtata aatgtatctc
     2581 gcatacttaa ggaacttgga aatgataata catctttagg ttttataagt ggttttactg
     2641 gagaatatat aataagaaca ttggaagaaa aagaattgaa gacagatttt ataaagataa
     2701 aaagtggttt ttcaagaata aatgtaaaaa taaaggcgtt aaaggaaact gagattaatg
     2761 gacaaggtcc aaatatagat gatgaagaca ttgatacttt atataaaaaa cttgataagc
     2821 taaatcaaga tgatatttta atattggcag gaagtatacc atctacttta gatgaaaaac
     2881 tatacgaaaa tataatggct agattagaaa aaaagaatat aaaagttgta gtagatgcaa
     2941 ctaaaaatct tcttcttaat gttttaaaat acaaaccttt tctaattaag cctaataacg
     3001 acgaattaga agaactattt ggtgttaaat taaattcaat tgaagacatg gtaaaatatg
     3061 ctagaaggtt aaaggaaatg ggagctataa atgtcttggt atcaatggga aaagatggag
     3121 cattgttgat tacagaggaa gatgaagtgc ttataagtga tgttccaaaa ggaaaagtaa
     3181 aaaattctgt aggagcaggt gattcaatgg tagcaggatt tatatctggg tatttgaata
     3241 ctgggaaata tgattatgct cttaaattgg gagcagcttc aggtagtgca actgcttttt
     3301 catatgactt agccaaaaga gaatacattg ataaattggt aaatgaaata tctgtaaaga
     3361 agttttaaaa tattaaaaaa tatatagaaa ggtaattaat atttatgaaa attatagatt
     3421 tattagatga aaagtcaatt aagttaaatt taaattcaaa aaccaaatca gaagcaatag
     3481 aagaattagt agatttggtc gcaaatagtg gaaatttaaa tgataaagaa aactacaaaa
     3541 aagcaatttt ggctcgtgaa gaaatgagta caacaggaat tggagaaggt gtagctatac
     3601 ctcatgctaa aaattcttca gttactaaag cttgtatagc agcagcagtg tcaaaagaag
     3661 gtatagatta tgaatcgttt gacggaagtt tatcaaatct attttttatg atagctgcac
     3721 cagacggagc taacaatact catcttgaag tattatcaag attatctaca atacttatgg
     3781 atgaagactt tagaaataaa cttataaatt caagctctga aaaagaattt aaggaaataa
     3841 tagataaaaa ggaaagagaa aaattcagtg aagaatatca agatgagaaa gtggctgaaa
     3901 aaaatataat agatactaaa gagaatgatg ctaataagta tcctaaggtt ttagcagtaa
     3961 cagcatgtcc aactggaata gcacatacat ttatggcagc tgaaagttta aataaaatgg
     4021 cagaaaacaa aggtgtatca ataaaagtag aaactaatgg ttcagcaggt gttaaaaata
     4081 agcttacaaa agatgaaata gaaaatgcaa catgtataat agtggcagca gataaaaatg
     4141 ttgagatggc tagatttaat ggcaaaaaag tcataaaaac taaggtggct gatggtatac
     4201 acaaagcgga agaacttata gacaaggctg taaatggaga tgctccaatt taccatggag
     4261 gagatggaag tcacaacgaa tcaaatgaag aaagtgaaag tggatttaga aaagtataca
     4321 aacacttaat gaatggtgta tctaatatgt taccatttgt tattggtgga gggatactta
     4381 tagcgatagc ctttttactt gatgattata ctattaaccc ttcaaacttt ggttcaaata
     4441 cacctatagc agcatttttt aaaggaatag gagataaagc ttttggattt atgttacctg
     4501 tacttgctgg atatatagca tactctatat ctgatagacc agcgtttgtt gtaggatttg
     4561 taggaggtgc tctagcaggt gatggtggtt caggattttt aggtgcacta cttgcaggtt
     4621 ttatagcagg ttatttagta gaagggctta agaaaatatt tagtgtacta ccagcttcat
     4681 tggaaggaat aaaaccagta ttgttatatc ctttacttgg aacacttttg atgggaatta
     4741 taatgacatt tttagtaata cctccagtta cagcaattaa taatgcaatg gttggatttt
     4801 taaatggttt aggtggaact tcaaaaatat ttttaggatt agtattaggt ggaatgatgg
     4861 ctgtggatat gggtggacct gtaaataaag cagcatatgt atttggagtt gcatcacttg
     4921 aatcagggca gtttgaaata atggcagcag taatggctgg tggtatggtt ccgccacttg
     4981 ctatagctct tgcaactaca ttttttaaga atagatttac taaagaagaa agagattctg
     5041 gtaaagttaa ttatgtaatg ggattatcat ttgttactga aggagctata ccttttgcag
     5101 ctggagaccc acttcatgtt ataccagctt gtgttggagg ttcagcagtg gcaggagcac
     5161 ttagtatgtt gttcaatgca gctcttcgtg cacctcatgg aggagtattt gttataccag
     5221 tggttaccca tccatttgca tatatattag ctatagctgt aggtgctttg gttggaatga
     5281 tgcttttagc attacttaaa aaaccattaa atcaagaagt atagcaatta aaggatattc
     5341 aagaacttaa aatatgatgt tttataaaaa ttaatatatt gctgaattat tttaaaataa
     5401 ggattttatg aggctgttat ataacgattt gtaattgtta tcttgacagt cttttatttt
     5461 tatataagta aaataagtgt gttttgcttt atttgtattt aaattgtttt taagttagaa
     5521 tataaagaaa attatatatt attttaatat tcactcgaac tagaaaataa tatttgttgt
     5581 atttttttgt atataaaata tattgtaata ttaaaaaaat aatagtaaac tgattgcata
     5641 aaaatgattt ttatataaaa tttaagcaga agaataaatt tctaacgaaa ttggatattt
     5701 cttctgtaaa tacatattca aaaaaagaat tataagagtt tagtcagcag tcgtgtaagt
     5761 aataaggact ttataaatat atagaaatat aatgatatta atataaccaa gcgattttta
     5821 atttagcttt ttaataagct tattttttat actatttata ataaataaac tccatgatgg
     5881 gaaaactatt actatttaat atgtaaagga gtattttaaa tgaatgaatc atattggttt
     5941 ttaaactcaa gtccaaaaga atataacaaa ttaggtgaaa atataaaaac agattgtctt
     6001 atagtaggtg gtggaataac gggattgaca actgcatatt tattagcaaa agaaggtaaa
     6061 aaagtagtgc ttgttgaggc tgataaaata ggatatggaa cttctggaag gaatactggt
     6121 aaggtaactt gtcagcatga tatattttac tctaagatag agaaaaaata tggattagat
     6181 aaagcaaaat catattataa tgcaaataat gaagctttaa atttagttga acaaataata
     6241 gaagaaaaca atataaaatg tgattttaaa agggaaactt cttttgtatt tacagaaaaa
     6301 gaggatacta taaagaatat taaagatgaa tatcgtacat gtaaaaaaat aggaataaat
     6361 tgtgagtatc atgaaactat agaaaatatt ccattagata taaagggggc tattagtttt
     6421 actaatcaag gtcaatttaa cccaaagaag tatattgatg gattggcaaa agcagcagta
     6481 aatttagggc taaaaatata tgaaaataca ccagtagtag accttgaaaa aggaaaaata
     6541 tgtagggtta aaacaagaga ggataatata atagaagctg agaatgttat aatttcatct
     6601 catagtccat ggtatgatgg attgaatttt tattttgcaa aagaatatgc agagcgtgct
     6661 tatttaatgg ttgcagtttt ggaaaataaa ttagcagatg gtatgtttat aagtatagat
     6721 gacccatcaa taacttttag acaatataat gatggaagtg aaaatttact gatttttgga
     6781 ggaggagacc ataaagttgg tcagggagga actgagaaag aaatatttga tgatttagag
     6841 cattatggta aagaagtctt taaggtaaaa gattttaagg ggaaatggtc tgctcaagac
     6901 aatatgagtt ttgacaatgt tccttatatt ggttatatca acaaaagaga agacaatatt
     6961 tatgtagcta cagggttctc taaatgggga attactaatg gaactgctgc tggaataata
     7021 ataaaagatt tgataataaa taataattct gattataaag atacttttaa tccatccaga
     7081 ctaggtagct acttttcaaa agattttata aaggaaaatg caaacgtagc aataaattat
     7141 gtaagtggaa aattaaaaat aggtagtgga gatatgccta aaaataatgg agaaggaaag
     7201 attgttaata ttgatggaaa aagatatggt gtatataagg atgataatgg agatttttat
     7261 attgtagaca ctacatgtac tcatttagga tgtgaactta attttaacag tgaagaaaaa
     7321 acatgggact gtccatgtca tggttctaga tttgactata agggaaatat acttgaagga
     7381 ccagctctta agccattaaa actttatgga catggtgata atgatgttaa tcctaagtta
     7441 ttataaaatt atttttagga aggtaaagtg tatatgaata aacttttaaa gccaataact
     7501 atactattgt atatagttta tattttatct gccgtatttt ttgtagcaaa caaagaatat
     7561 ggaagtctag gtctggtagc aattagttta gttggtactt tcattttgag ttttataaat
     7621 aagcaaacgg aaagattatt gagtaaagaa ttatatataa tgcttgcttt atttataatg
     7681 ttttcatcat tgttaggtac ttgttttaat ttttatgata taaattatta tgatgatttt
     7741 ttgcatttat ggtcaggtat aatatcttgt attgtggctt tttctataat taaatacttt
     7801 tatacacaaa gagagataag taaaatgagt aaagtgtttt tagttatatt tttatttatg
     7861 tttagtatgg gagtagcgag tttatgggaa ataggtgaat ttttaatgga tacttttgtt
     7921 gggactacta cacaggccgg agggttagaa gatactatga ttgatatggt agatgcttta
     7981 ataggcacaa ttataactat tccttttata gtaaaaaaat ctaatatata gttttaaatt
     8041 ttttatatta attataatgg atttaattaa tcatgttgag tttcaaggtc tatatgatta
     8101 attaaatcca tttttgttat ttataattat tattgaatat atttttacat ataagatata
     8161 aggtgataga tagaaattgt tggattatgt aaataattaa tatataatac cattatgggc
     8221 aataaataca aatcaaatga taatatagtc tatttatgta aatgttatat tgtatactaa
     8281 gtataatagt aagttttttg atagtggtgt agaaagtaaa aatctactag cctaaattga
     8341 tgtatggatt agtttaggaa cagtaattgc atatcttaag tttgatgtca tgttgggcta
     8401 ctagaaatag gtcatctttt tcacttgaat atcttttctt taaacatgga gagtatcata
     8461 tcaaaaacat atgaaaatta agtgatttat aagaacagta atattttata tgatagtata
     8521 gaatagtaat aaagtattag gaggaacatt gagtgttaaa aaagtggttt ggtattgtga
     8581 aaaaaagaca aaaaagtgag tcagcaaaag aagaaggtga agtaatatta aaaaacgaaa
     8641 aaatattatc tgaagaaaag ttgatagatg aagaaggagt tgtagttaat attgataatg
     8701 aaatattaac taaagtagaa gtagtaaatg atgataatga aatagaagaa aaaataatag
     8761 aagaagattg gttaattagt gaaaatacca taaaattaga tgataaagaa gcaattatta
     8821 atgataaaaa catagaatta tgtaaaaaag aagttcaagt tgaaggtgaa aaaatagatt
     8881 taaataagtt tgaaggactt gaccaaaatg aaaattataa tctagaaaaa aatgttattg
     8941 aagaaaaaga agtaagtgaa tgtttgacag aagaagattt agagtacata aaagaaatta
     9001 aaataaaaag aggaaaaagt ataaaagcta taaacttgta tactaaagaa gagtgggttt
     9061 ttgacactca tatacagtgt agtaaaaaac tcaaagttcc attagggtac ataagagaaa
     9121 atttaaaata tggatatatg gattactttg gagatgcaat aaattattta agtgaagtat
     9181 taaatataga tgaatactgc aaaagtgaat ggagctatct cgataatagc aaatctccat
     9241 ctgagatatt taatattcta aacaataaaa tatttagtat aaggctttct aatgaaaaaa
     9301 gaaatgaaat tttgacaaat gataaaattg aagcattaaa aatgaattat agatttgaat
     9361 gtattgatga agaatatgat gaatatttta aaaaatataa gtctataatc aaaagaggtg
     9421 gaaagaaaaa agttgaatta gtaaataaaa aaggtgacat tttagaaata tttaagtctt
     9481 tagaagaatg tgccatttat ttgcaaaagg aaaagaatga agttatacaa atgttaaaat
     9541 atggagatac aaaagtagga agaaacttta taaggtatag tttgagaagt atttaatttc
     9601 attttaaatt cataagagtt tcatttctga ttcacacatt taatattatt ttaatgtaaa
     9661 ataataaagg tgaagtattg tacaattaaa attaaggagg gtattaatgt ctgaagaaaa
     9721 aaatccaaaa gaaaatacat tagatgaatc taaaaattca gataatgtaa attctaaaaa
     9781 agatgatgtg tcagatgaaa aaaatactga taacaaagtt aaaaaaaggg aaataaagct
     9841 aaacaacaaa acacttaaag ctattgtagc aattgttgca gtaggagcta tatgtttagg
     9901 tggaggctat atttttggca aagaagctgg aagaaaattg cctgctactt caaaacacta
     9961 taatagcagt gaggtagtag ctactattgg ggataaaaaa ataacaggtg aaatgttaag
    10021 aaagagaatg gagccattat tttatttaaa tgcaaaaact actatgactg atgacgaaat
    10081 acgttcatat gaatcaaata tgattgaaac tatgattaca tctgatatat tatcctctga
    10141 agcagcaaaa gagaaaataa gtataactaa tgaccaacta gatgctcagt ataataattt
    10201 aatgagtagt atagaatcag caatgggaat gactaaagaa gagtttttaa aacagtttga
    10261 tttgactgaa aaatatataa aagatgatat gaaaaaagag ctagtagcat caaaatattt
    10321 aaatgaaaaa tcaaaagtta ctgataaaga agcagagaac tattacaata aaaacaagag
    10381 caattattta caagttagag cttcacatat tttaataaaa actgttgatg ataaaggtaa
    10441 gcaagttagt agtagcaaaa aagctgaact taagaaagaa gctgaagaaa tacttaaaaa
    10501 agcccaagct ggggaagatt ttgctactct agctaaaaaa tactctgaag atagtagtgc
    10561 agaatcaggt ggagatttag gtttctttgg taaaggtcag atggtggaat cttttgaaaa
    10621 agcagccttt gcattgaaga agggagaggt atctaacaaa cttgtagaaa gtgattatgg
    10681 atatcatata attaagaaaa ctgatgaaaa atatcagcca tttgaagagg taaaatcaga
    10741 tttagtaagt agtttaacat cagaaaaaca aaacctactt atacaaaatc taaaagaaaa
    10801 atataatgtt aaaattacag ataaatatca aatgaaagct aaagaataga taaagtcaat
    10861 ttattaaaaa aaagaaaaat taactgtatg gataaaagct atttttactc tcaatataga
    10921 gagtataaaa tagcttttat tattttgcaa taaaatctat ttatatatat gaagtgacaa
    10981 agaaataaca tgcaaaaaga tattaaaaag aaatattttt aatttgaatt ttttcaataa
    11041 aaatttacaa aaatgaaaaa ataaacaaaa aagaattgaa gatttaagtt gttgtttaaa
    11101 tatatatata ttaagatttt ctgctgaaga tactaaaaaa ataatatttt tcataatttt
    11161 aaaaataata ataaaaaaat gaaaatacag gcgataatct attgagtaaa catagaaaag
    11221 atgatattat aagtatgtgc taaaatggtt aaagcaatat taatattaaa tttaactata
    11281 aaacaaaagg gggcgttttt ttatgtcaag tacagaaagc gtatctaaaa aaagtggtca
    11341 tccgaagagt ttttggctta tttgcatgac aattttgtgg gaaagattta gttattatgg
    11401 tttaacagct ttattggtat tattttttac agcaagtgta gctcaaggtg gtttaggtct
    11461 ttctactcaa gaagcaacat ccatgtttgg cttatttaca ggtcttatat atcttacacc
    11521 attagtcggt ggctggttag cagataaagt tttaggtcaa caaaaatgta tttctatagg
    11581 tgcactttta atagcaatag gagatttcgt actatttgct tcatctacat ctattgcaat
    11641 ggtttgggta ggtctatcaa taattatttt aggaaatggt ttttttaaat caagttgctc
    11701 aaatatagtt ggggatatat atcctaaaac tgatgtgtca agaaaagatg cagcatacag
    11761 tttattctat atggcagtaa atgtaggagc atttatagct ccaataatat gtggattgct
    11821 ttctgataat gtatttgcag taagaggagc aagtggagat atagtatctt atggatataa
    11881 gatggcattt ttaatttgtg gtataggcat gatgttaggt atgattatat ttacacttct
    11941 tgcaccaaaa ttattaaatg aagtcggaaa atatcctgtg actaaaggta ataaaggtga
    12001 aaaaattgag tatggaccac ttactaagtt ggagaaaaat aggataatag caatggttat
    12061 tttattttta tttgtggtct tattctggac agcatactat caaacacaaa gttcttttat
    12121 gatttatgta agggataatg taaatagaac tctatttgga tttgaaatgc cagtagcatg
    12181 gcttacatca ctaaatgcta tattatgtgt ggctttatgc ccagtattag ctaccctatg
    12241 ggttaaatta tctcatacca aaagaggtga tttctctatt ccagttaaaa tgggattagg
    12301 aatgataata atgggtgttg ggtttatagt tatggtattt gctacattag ctaatggtcc
    12361 agatggaatg gtaaaggcta gtatattgtt tatagtattg acttatatat ttacaacagt
    12421 aggtgaatta ttcttatctc ctataggact tgcaatgttc aataaattag ctccagctaa
    12481 gtatgctacg ttgtctatgg gagcctggta tctaacaagt ttttttgcaa gtttattatc
    12541 aggaaagatt gctggtttta cagccacact tggtttttta cagatatttg gaggaatagc
    12601 aacagtttta ataatatttg gtttaatatt attgggaata agaaatgtat taacaagatt
    12661 aatggctatg gatttactaa caaaagaaaa ataattcatg acgaattatt gtaaataaat
    12721 gaattacttt acaataaagg aagttacatt taaatataaa attaaatgta atttcctctt
    12781 tgattatgaa aaaaagcttt acacaaatag atattataat taaaattata attgtgataa
    12841 ttagagtgta taagatttat ataaattata caaaaaatat ttatgtaata aactttacat
    12901 acttatatat ttagttattc aaactattat ttcgaggagg tcttgttgtg aatataaaag
    12961 atagattaag tggattaaga aaatttatgg aagaaaaaaa tatagatgcc tatatgattc
    13021 catcttctga taatcaccaa agtgaatatg taggagatta cttcaaatca agagaattta
    13081 tatcagggtt taatggttca gcagggacgg ttattgtgac taaagacgaa gctgggttat
    13141 ggacagatgg aagatatttt atacaggcag aatctcaatt agaaggaagt acaataaaat
    13201 tattcaaaat gggacaagaa ggttgcccaa ctacagatga atatttatat aaaaatattc
    13261 ctgaaggagg aactttagga tttgatggta gagttatatc tgctagagaa ggagctacat
    13321 tagctgaaaa attatctaaa aaaggtataa agatagaata tcagtatgat ttaatagata
    13381 gtatatggcc agatagacct gctttatcag atagtaaagc atttttatta gatgttaaat
    13441 attgtggaga aagttttagc tcaaaattag ctagattaag agaaaaaatg agtgaaaaag
    13501 gtacttctac tcatgtaata actactcttg atgatatagc atggttattc aatataagag
    13561 gtggagatgt taaatataat ccagttgtac tttcttatgc agtaataact ttaaaagaag
    13621 tttatctatt tgttgatgaa agtaagttaa atgaagaaat actaaatgaa ctagctaagg
    13681 aaaatgttca aataaagcca tataatgatg tgtatgaatt tgtaaaaaat atagacaaaa
    13741 ctgaaaaagt tttattagat ggaactaagc ttagttatac aatttacaat aatatacctt
    13801 gtgaagttga gaaagttgat gagttcaatc cagtaatgtt ttttaaagct caaaaaaatg
    13861 aggtagaatt agaaaatata agaaattcac atgtaaaaga tggtgtagct ttcactaaat
    13921 ttatgtactg gttaaagaaa aatgtaggta agatggaaat cactgaaata agtgctactc
    13981 aaaaattaga ggacttaaga agagagcaag aaggtttctt tgagccaagt ttcaatacaa
    14041 ttgctgcata taaagagcat gctgcaatga tgcactatag tgcaactcca gagtcaaatt
    14101 ataaattaga ggcagaagga ttatttttag tagattcagg tggacaatat tatgatggaa
    14161 ctactgatat aactaggact acagttttag gacctataag tgatgaatta aaactacact
    14221 ttacttctgt agcaagagga atgataaatc tttctaaggc taagttcttg catggttgta
    14281 gaggatataa cttagacata ctatctagaa gttgcatgtg gaatatggga attgattatc
    14341 aatgtggaac tggacatggt ataggatttg tgctaaatgt tcacgaagct ccaaatggat
    14401 ttagatggag agtagtacct gaaagatttg atagtgcagt tcttgaagaa ggaatggtaa
    14461 ctactaatga accaggtata tatatagaag gttctcatgg tataagaaca gagaatgaaa
    14521 ttgtagttag aaaagctgaa aagaatttct atggtcaatt tatggaattt gaagttgtta
    14581 cgttagctcc tattgactta gatggtatag caccagaatt aatgaataag gatgaaaaag
    14641 attatttaaa ttggtatcat aagttagttt atgataaaat atcacctttc ttaactgatg
    14701 aagaaagaga atggttaaaa gtttacacta gagctatata gtttgtacta gatacaataa
    14761 aaatcgaggt attataatgc ctcgattttt tattgtatat tttattaact ttaaaaaatt
    14821 tttaatttga taattctact aattttttat tcattataag tagtataatt ccaaatatca
    14881 ataaaaatga tggtatcact atgaagactt gtaacatacc aagttggtct ataatagctt
    14941 gcgtatagcc agataattta tttgctgcaa atttgcctaa aaaccaaaca cccattagga
    15001 atgaaatata cttttcaggc gaaagtttat ttaccatacc atacccgact ggagaaaagc
    15061 aaatttctcc tatactttgg aatgttaaaa atccaactac ccaaaataca cttgctttgt
    15121 gaattgaatt agggtctgtt cctgtttgta taactgctac tatcataaac aaaaatgcta
    15181 tggctaatag tataaaacct aagctcattt tttttggcac acttaaatcg ccttttttag
    15241 tttgagataa ttttacccat actaaagcag agataggtcc aagaataaca caaaggagac
    15301 cattgtatga atctatccat gaagtaggaa tttgaaaatt gccaacagta agatttatgt
    15361 gttcctttgt atagagtgca atagacatag aggcttggtt atatgctatc caaaaaaata
    15421 ctgtgaaaaa agctaacacc aatattacta ttattctttt tttctcaatc aaagttaaag
    15481 gtcttgaagc gagcattttc ttatattcta gtgattttct tatagactct ctcccgttaa
    15541 tagggtcatt attcaaaggt ttataaaact ttctgtttcc aaatataaag aagaataaac
    15601 ctattagaac cgtaattgat gaaaataaaa atacatatct atatccatac atacttatag
    15661 ataatccgct tttcatagca aaccattcat tagcaactaa accgcatatt aaagggccaa
    15721 ataaagtacc tagattagta gccatatacg taatagagaa agctccatct tttcttgggt
    15781 catcattggt atataagttt ccaaccatag tatgtaagtt tcctttataa aaacctattc
    15841 ctaatccaga taaaaatatc atgatgttta tatccatctt actatttgct atgtatccta
    15901 gaaaataacc aattgaaacc attagcattc caagtataat acagtttttg ggacctaaaa
    15961 atctatcact gacccatcca ccaataactg gagagaaata agtccatgct aaaaaagatg
    16021 caagcattga tgcggattct gctggtgtta accctaaacc acctttggag acttgttcag
    16081 ctaaaaacaa taataatacc aatttcatac catagtatgc aagtcctaca aaggtaaata
    16141 ttgaacagca gaaatataaa tctctaggtt gtttaagttt ttcttgcgtt tttaaaactg
    16201 acatatgtcg agaacctcca gataaatagt ttaacaaaat tttaccatac tatatgagta
    16261 tatgtttttt tcatatagac gtcaacttgt aagataattt aattaagtcg aaatatatgt
    16321 aaaaatagta tcatttttgt gtattcagta atattttttt atgataatat atgttattat
    16381 tatattaaaa tacaaacata tttatggaaa ggatatgcca atttagtagt tagattgatt
    16441 gtttggcagg tgggatgagc tatgataaga aagaaatctg aattacaagt agaagtaaaa
    16501 gaaaatttaa atggtggtat aggaaaggtt aagcttgaaa acataataca aaatgaagag
    16561 cttaaaggaa aaggaagact atttaaaaga gtagctttac cagtaggaag ttcaattggt
    16621 gtgcatgacc atacaacaga ttttgaagta tattatatac taaagggaaa aggtaaagta
    16681 tttgataatg gggaatttgt agaagtaaat gagggtgatg tagtgtatac agctgatggc
    16741 gaaaaacatt ctatagaaaa tataggagaa gaagatcttg agtttgtagc actagtttta
    16801 tatatgtaaa atatggagga ggagtcatga caggcaagat agaagaaatt aaggacaaga
    16861 taaatagatt ttgcaactcc aatttaaatc aagaatacaa agatataagc tttaaaattt
    16921 tgcaaaacct tttagataat aataaagaga taattcattc ttctagagct gatatatggt
    16981 cttcagctat actaaatata gttttagaac aaaatctttt atacaataag aagcatccac
    17041 tacatataac aaaaaaagag ttttcaaaac aaataggtgt ttctttaaat actataaata
    17101 ataaatcgtc tttaataaaa gatgtttgta gtattgactt tttaaatcaa gatactatag
    17161 ctatttctaa tgtagaattt tgggtaaaag agactaattc caaatcaaag tctgtagatt
    17221 tagatttaga aaagaagaaa atactatata aaagatatat taagctatca caagatgcga
    17281 atagtgatat tgaatcaatt agatatatgg aggaagctgt aaatataggt aaaagtatga
    17341 ttactaaaga agataaagaa cttggatttt ggaaaggttt atctaccaga gcctatatga
    17401 tagcacttga atcccttgct agaaagttag aaagtattaa taatctaaag gagtccaaaa
    17461 aagtattaga atatttaata gaaattaatc ctagtgatga gcagggaata agatacaaat
    17521 tattaaatgt attaattaga ttaaatgata gaacttcaat aaataaatta tttgaacttt
    17581 ataaagaaga aaaatctgct acatggatgt acagtaaagc tctttattac tttaaaaata
    17641 aaagtatgtt tttggcaaat gattctatta aggttgctag aagtaaaaat aagtacgttg
    17701 gattatattt gttagattgg cgaaatgctt ttggtagaga atttgttaca gaggaagaaa
    17761 aggcagaagc tgtctattac tatgatgaaa acatagtgat ttggaatgaa gttaaaggtt
    17821 ctatggattg gctattaaaa aaaatgttgg aattttcata aaaaaaacta ctccttactt
    17881 ttatataagt caaaggagta gtttttaatt tatacatcta gttttaaatc ttcaggtttt
    17941 attagacctt tttttctcat aaattctgaa atcaacaaag ttacaatagc aggaagtata
    18001 aaattaagta aaagtatacc aacccacata gatatacctc cttttccagc actttgcata
    18061 gcagttactg ttccaaattg tccaaccaat ccacaagtac ccataccaga accaatagga
    18121 atattctcca ttttgaatat tgttgtagat aatggtccaa gtaatattga agctacagta
    18181 ggtggtatcc aaattttcca attttttatt atattaggta cttgcaacat agatgtccca
    18241 agaccttgtg ccacaaggcc accaactcca ttttctctaa agctcataac agcaaagcct
    18301 accatttggc aacaacaacc tacagttgct gcaccaccag caagaccacc taaacttaac
    18361 atcatacaaa tagctgcact acttataggt aatgtaagag ctattccaac aagtgcagag
    18421 actaaagctc ccattattat aggttgcata gttgtagctt gcattattat atttccaaat
    18481 gaagtcataa aagcagaaac agctggacca ataagttcag ctacaagtac tccaattagt
    18541 attgttacag caggtgtaac caatatatct atttttgttt cttttgaaac taattttcca
    18601 acctctacag caaaaagtgt agcgacaaat gctccaacag gtcctcctaa ttcattacca
    18661 caagctccaa caagtgcaca agaaaatagt acaagtggag gtgcttgaag tccatacgca
    18721 atagccactg ctatagctgg accagtaacc tgtttagcaa gagggcttat aacttcagta
    18781 aaaagagaaa tattgaaatt atctcctaat gtattgaaaa ttgttccaat taaaagggac
    18841 gaaaaaagac cgagtgccat ataacttagt gcgtcaataa gatacctttg aacagaaatt
    18901 tcaatatttt ttcttttagc aaatgatttg aaatttcttt ttttataatt gatttccaat
    18961 ttaaaatcct cctcatataa tataagtata atttcttttt aattaattat ataacttttc
    19021 agctgacaag acaaatgtta tttcactaaa attagactat tgtaatagta agaaattaac
    19081 attaatttta gttttaaatt ttaaatttat ggtttataat tagtataggg atattctgaa
    19141 atataataat tttccagttt atcccaatat ttaacttagg tagattgctt acaaaacaaa
    19201 tgattatata ttaggctaaa aggaagtgga tagatgatat ttgtaaaaaa taagaaatac
    19261 agaaaaattg ccataattat atctattcct atattgcttg ttgcgcagta ctaccttttt
    19321 aaatttggaa tacttagacc aatggtaaag ggagtagaaa ttgaaattgt agatggggaa
    19381 tatgttaaag atatagataa atatgtagta aaattaaatg aaacagttac tttgtctaca
    19441 ggtgaatata ttaaggttcc ttcgtatgct aaaaatccaa atatttggtt taatgtattg
    19501 gataactcag ggactttaaa aatagatgga aataaaatga cagcattaaa ggttgggtat
    19561 tcttctgtgg gtatcatgaa aaattcaaga gtattaaaaa aggctactat aaaagtagta
    19621 gacccagagg tagaatcact agatatggag attaatgggg atttaaaaca tgttggtgat
    19681 agtgctacta tagaaagtac aatagaagtt gattatgata agtttaaaaa atcatataag
    19741 ccagtttata agagtagcaa tgaaaatatt ttaaaaatca aaggaaataa agtaagtgca
    19801 gttggagttg gtaaagctac aatatatgct aagtgtggaa ataaagaaat tgagagaaca
    19861 tttaggattc aagctagagt tgctgaaata aatatggatg atataaaaat agaagttgac
    19921 cagaatgaaa aattgaaacc agatataata acttctccgc ctggtttaga accaccaaaa
    19981 atatattatg agttagtaga ttcaaaatta cctgtagaaa gagcaataag tttaagtagt
    20041 aatggaaatg ttgtagggct tagagaaggt aaagataggg tgagaataac ttgtggagat
    20101 aaatctaaag taataacagt aacagtagtc aaagaaacta taacgaatga ctatatacaa
    20161 aacttggttg gttcacataa aatagtaaac aataaagtta ttattaaact tgaatgggat
    20221 tatatgaaag atgtctttga ttatgatata tatcttaaag ataagttgtc aggagaatca
    20281 tttaagaaaa ttaaatctat aactataaat gaaagtgatt taggtaagtc taacaaggta
    20341 tatgcaacta tagaagtaga tatgaagggt aatcaaaata tagattttga tatttatgtc
    20401 atagggaaaa aggattcaga tacaactaag ccaagtaatg taataaatat taccaatgga
    20461 aatggaaatt caaataatga taataatatt aaagatatga gggtagaaaa tatatcagct
    20521 aatgttgata gagataataa tgtcattaga gttaactgga gtagtatatc tcataaggac
    20581 tgtacttaca gtatatatgt aaaaaataat actaatggag atggagaatt tactctatat
    20641 caaagtgata tacagggaaa tgagcatact ataagtattc ctgaaggaga tttaaatcta
    20701 gatatttatg ttgttgcaaa ttataatgga aatagctctc aaaatagtga tgttataaat
    20761 gtaagataga tttgtataca aattgaaagt gttgagttta tttaaatatt aaattaagaa
    20821 aaaggatagt atagggtaat tatactatcc ttttttgtta caatatatag gtttaaaatc
    20881 tctagtaata taaattataa aaagtcttat ttacacaaat ctatagatat tttttttatt
    20941 aatcaatatt gtcttaaatt gaacttagtg cggcttctat tgcatgtatt actgtcgtat
    21001 caaatagtgg aatagaagtg tcattttgtt taattaaaag acctatttct gtacatccta
    21061 atataacagc ctctgcacct tgtttgccaa gcttatctat aatagataag aaagcttttt
    21121 ttgaagattc agatataatt cctaagcaaa gttcattaaa tattgtgtca tttactatta
    21181 tacggtcttc ttcatttgga attaagactt caattccatt attaataatt acatttttat
    21241 aaaaatcttg ttccattgta tatttagtac ctaataaggc cacttttttt atttcttttt
    21301 cccttaatac cgtagcagtt acatctgcta tgtgaagtaa tggaatatgt atactttctt
    21361 gtattttatc tgatacctta tgcatagtat tagtacagat aacaataaaa tctgcccctg
    21421 cctcttgtaa tttaattgca gcatcagcta aaattttggc gcttttttcc caatttccac
    21481 tagattggca ttcttcaatt tcttgaaaat ctacactgta aagtatacat ttagaagagt
    21541 gtagtccacc taatctttct tttattactg tattaataac ttgataatat gtaatggtac
    21601 tttcccaact cataccacca attaagccta tagtcttcat attatacctc tcttatttat
    21661 ttattttgaa atagctattt acaaatacaa gtatagcatc taaaatagaa gcatacaatg
    21721 ataaaattgt atggagtaca attataatta agaggagtaa ttatatgcca ataaattctt
    21781 ttgaaaacta tcctatgaca tggaaaccaa aattagataa ccgaaaacca ccaatatata
    21841 aaactttagc aatgttatta gaagaagata ttaaaagagg aaatttaaat cctggagata
    21901 aactgcctcc acaacgggaa ttagcagatt ttctagattt aaacttaagt acaataacac
    21961 gagcatttaa actttgcgaa gaaaagggac taatatgtgc aaaagtggga aagggaacat
    22021 tcatttcttc tgatgtaaat gtaagtaata cattattata tcaaacggaa tcaaaagaca
    22081 taattgaatt agggacagtt catcctccgt atgagcaaaa tacatatatt attgacttta
    22141 ttaaaaatgt actaaaacaa ccagaaatgg ataggttttt acaatacatg tctccatctg
    22201 gcacatatat gcaaaaaaag tcaattgcaa aatggataga aagaaataat gtatacacca
    22261 gtgaagaaaa tatattatta tctacaggag ggcaaaatgc tatatgtgca actttactag
    22321 gattatttaa agctggtgat agaattgcta cagattcttt aagtttttct ggaattaagt
    22381 caatagctaa aatgataggt attcaattag tcccaattcc tcaagaaaat aatgaaatat
    22441 cgattgaata tcttgaaagt tattgtaaaa atgaaaatat aaaaggcata tatcttatac
    22501 cagattatca taatccaacg acacatacta tgtctgattt atctcgtaaa aagatagcca
    22561 agatagcaaa gcaatataat ataataatta ttgaagatgc tataaatagc atttttagag
    22621 atggtataca aactcccata ttttctttag ctagtgataa tactatatat atttttagta
    22681 catctaaatt tttatgtgct ggtcttagag tagcatttgt agttgctcca aaacgatata
    22741 tagaaaattt agaaaatgca ctatataata tgaatctaat ggtttctcca tttacagcag
    22801 aaatagtaca ccgtttatta tattctccta ttatagataa aattatagaa gagaaaagag
    22861 atgcaattat agaaagaaat gaagttgctg ataaagtttt gtcagattat aatttgattg
    22921 gtgataagaa ttgcagtttt cgttggttac ttcttcctga tgaattggat ggaaaatcat
    22981 ttgaaatttc tgcaaaaaat ctaggagttc aagtatattg tgctgaacga ttttcagtag
    23041 gaaactctac agttccaaaa gcagttcgta tttgtgtaac agctccaaaa gatgtagaag
    23101 aattagaaaa agggcttaat ataataaagt cacttcttaa gagttaaatt tattttacta
    23161 ttatttaatt aaataaataa aaaggcggag aaatttatta taataaacct ccgcttttat
    23221 tatttaatga aatactttac tttttattaa aaaatttaat tttaataatc ttgaaaatat
    23281 aatcgtttta tggtaaaata attcttaaaa atagaaaaaa ttaatcattt gttaaaaaaa
    23341 atgcataatt tattgtaatt tattgacgaa ggttgaaaaa tattcataaa tgtgcgaaat
    23401 aacagaaaaa atgcaaaaat taattcaatt tcatttgtta taaaatctat atggcaaaat
    23461 taaatctgcc tatcagaatg atataaacac accagaaagg aggacgctat caaataatac
    23521 aagtagttaa ctttgatagc aaaaaattat gaatgaacaa actagaatat ccttagagag
    23581 agctgctgaa ttaaaatcaa aaattgatga ttatattcag gctagaaaaa cgattaacag
    23641 aggtcttgaa aaagaagaag agataaataa acgaaaacag aaaatattaa gtatcttaaa
    23701 tggaactgaa gaggattgga ataactacaa atggcaatta tcaaatagaa taacagatgt
    23761 agatacttta tcaaaaatta taactctaac taaaaaagaa aaagaatata taaaagaggt
    23821 tggtactcaa tttagatggg caatatctcc atattatttg agtcttatag acccagaaga
    23881 tacatgtgac ccaataaaat tactgtctat accaacacat atagagttgg aagatgaaca
    23941 agaagatttg gacccaatgg gagaagagta tacaaaccca gcaggatgta taactagaag
    24001 atacccggat agattaataa taaatgtaac aaatgagtgt gctatgtatt gtagacactg
    24061 tcagagaaga agaaatattg gacaacaaga ttctcataag tcaaaagcta ttatccaaga
    24121 atctatagac tatatcagag aaaatgaaga aataagagat gtactagtaa ctggtggaga
    24181 tgctcttaca ttaaaagatg attatttaga gtggattctt agccaactta aagagatacc
    24241 acatgttgat tatgttagat taggtactag gactcttgtt acaatgccac aaagaatcac
    24301 agatgaattt tgcaatatgc taaaaaaata tcaccctgta tatataaata ctcattttaa
    24361 tcatccaatg gaaataacta aggaatctaa agaagcttgt gaaaagttag caaatgcagg
    24421 agttccatta ggaaatcagg cagtattatt aaatggaata aataatgata aatttgtaat
    24481 gagatgttta aatcaagaat tactgaaaat aagagtaaaa ccttattata tattccaaag
    24541 taaacatgta aagggaacaa aacatttcaa tacatcagta gatgatggtc ttgaaatcat
    24601 ggagtattta agaggatata catcaggaat ggctatacca acatatatag taaatgctcc
    24661 aaaaggaggc ggaaagactc ctttgcttcc tcaatacctt gtatcaaaag gaacagatta
    24721 cgttatgctt agaacatggg aaggaaaagt tataaaaatg gaagatgaac ctgctgtaga
    24781 tataaagaaa cttataaaag aacaagcgca ggattaaaaa agtatttaaa gtttataaaa
    24841 agaaacaact ttaaaataaa aagaaaatgg atgtcaaatt tatatcaatt tgcatccatt
    24901 ttttattagt tatttattat tttgttgttg attaactaat tcaagatatc cacttgggtg
    24961 gaagtaatat atctcaaaag tattttcatt tacaaagtaa ccaatatcac catctgcatc
    25021 tggtaaaaat acataaccat taagattttt agcttttaat gcttcaaaat cactagcatt
    25081 tccttgatat atgtaatcaa cttcattgtt gtattttact aaaagttctt tagcttgttc
    25141 ttgagtcaat ttagtatttt ggcttacagg aacattcttt tgagaatctg cataagaaga
    25201 ttcatttact ggtgcagtta ataacaaaca agataaaact aataaagata taagtgcttt
    25261 tttcatacta aaaccctctt tcatgtttaa ttatataaga ttcattactt aataatattg
    25321 tatgtttcct ataattaaat attaccatta aagagaataa tattacagtt acacagctgt
    25381 aacttttgat tacaaaatcg taattaaatt gtatttttat tccatttgta ttttatcatg
    25441 tctacgattt acaaactcac agaagtatat ctttataacg cccatcacag gagcagatag
    25501 aatcatacca ggtataccaa agaatcctcc accaacagta actgctagga ttgtaaagaa
    25561 tgggctaaga cctagttgtc cacctacgat ttttggctct ataaatgtaa cttcaacttg
    25621 ttgaattatt attaagtaaa ttaaagaagt taaagcaatt gttggattgg agaataaatt
    25681 aattattaca actggtgcca tacctattac tggaccaaaa tatggaacca tattcatgac
    25741 acccataagt gtaccaaata atagtgcata ttcagatttt aaaaagtaaa gaccaattcc
    25801 agaaagtact ccaactataa aagaatctaa aatcttacct gtaaagtatt taccaatatt
    25861 taaatttaag ctttgacata gttctattat aaagtctcca tattttttac ctaaggaaat
    25921 ataaactact ttttttgtaa acagtaagaa tttttctttt tctaataata tatagaaaca
    25981 aattataaaa cctaaaagaa attgtactat aaattttcca actgaaaatg tagtgctaaa
    26041 tatcccacca agtgaaccaa taagcaagtt actaaattta ggcattacac tcataatttt
    26101 gtcaccatac tcttttaatg tattagggtc aactgattgt aaactcttgc ctaagtcgaa
    26161 taaaaactgc tctgttttat ctatgtatgt aggaatttga gcaactaaat cagctaaact
    26221 atttactatg gatggaactg taaataatat aaacgaaatt agtataacta tgagtacacc
    26281 ataagtaaga agtaacgaat atattctctt aaaatttaat ttactttcta agaactttac
    26341 tagtgggttg aatatatatg ctaatacaaa tgctattata aatggtgtta gtagtgacat
    26401 taataaactt atcactccaa aaaaatattt gtaattatca ataactttaa tcaagatata
    26461 tgaaacaact acagtgagta caatatttag ataaattttt ttatcttgca aaataacaca
    26521 acctttctta tatttattaa atttagatat acttaaatct aagttaaagt taatatttat
    26581 agcttattat acaataaaaa gcagtattaa tatagtatga ttaatatgaa attataaata
    26641 cgttaaaact ttatgtttat agctaaaata ataaaaatta tttatattgt gtttatatat
    26701 aatctaaaat gaaaaaaagt ggtgcctttg attaaactaa gtttttataa tttaaatttt
    26761 gtacaataag ctatctttta ttattcttta aaatatatat ttcatttaat tatgacaaat
    26821 aaagataaaa attaaatatt ttagaggtga ttttatttag atatagaatt ttagaataat
    26881 actatacaaa tgtattgtat tattattttt atatcaaaaa tagtaataaa gtctatatac
    26941 atttagaaaa tactgtttaa aaggagtagg atttatgata aaaaaagaga tatctaactt
    27001 tagaggaagt agtgattatg tagtatcacc agaattgatg gcatcagtta atgttgctat
    27061 tgctcttgaa aagccacttt tgattaaggg cgaacctgga acaggtaaaa ctatgctagc
    27121 acaagcaatt tcaaatgaat taaaaaaaga tttagtaatt tggaatataa aatcaactac
    27181 aaaagcacaa gaagggcttt atgtatatga tactgttcaa agactttatg atagccaatt
    27241 tggaggagaa ggtgtagatg atattagcaa gtacataaaa tatggtaaac taggagaggc
    27301 ctttagctca aatcaacaag taattctttt aatagatgaa atagataagg cggatttaga
    27361 atttccaaat gacttgcttt gggaattgga taaaatggag ttttacataa atgagacaaa
    27421 agaaactgta agagctaaac aaagaccaat agttattata acttcaaatg cggaaaaaga
    27481 acttccagat gcttttttaa gaagatgcat atttcattat atagaatttc ctgatagaga
    27541 catgatggaa gaaatagtta aagtacattt tgataaagta gaagaacacc tattggaaca
    27601 agtaatgact actttttatt ggattagaag tttaaaggac atacaaaaaa agcctagtac
    27661 atcagagtta atagactgga tacaagcatt aactttgagt ggaatgccta ttgaaaaaat
    27721 agaaaaagaa gttccttttg caggaatact acttaagaat aatgaggata ttgaatctat
    27781 gcaaagacac ttatagttaa taggagctgg ataattatgt ttattgaatt tttttattta
    27841 ttgaggtcaa gaggattaaa tgtatcttta aatgaatgga tgactttaat tgaagcattg
    27901 gataaaggac tgtgctattc aaacttttca aatttttact atctttgcag gatgatttta
    27961 ataaaaagtg aaagtgattt tgataagttt gatgcagtgt ttttggagta ttttaaaggt
    28021 atagaacacc aagaagaaat tccagaagag attatgaatt ggcttaaaaa accagatata
    28081 gatttagaag agtttgaaag attagaacaa aatccaaata taaatcttga taaattaaga
    28141 gctaaattgg aggaacgaat aaaagaacaa gattctcctc ataatggtgg taattattgg
    28201 ataggcacag gaggcacttc agagttagga cattcaggaa aagggcaaac tggtatacgt
    28261 ataggtggaa attctactta tggtagagct gttcttgaag ttgcaggaga aagaaaatac
    28321 agagatttta gagatgatga agttttaaat atgcgtcaat ttcaagttgc actaaagaga
    28381 cttcgtcaat tttctactag aatagatgct ccaaagacag agcttgattt ggataagact
    28441 attgaagaga cttgtaataa tgcaggatat ttaaagttat tttttgagaa gccaagaaaa
    28501 aatacagtga agcttttatt gcttatggat tcaggtggtt caatgagagg gtatagcact
    28561 ttatgtaata cattatttca gtctgtaagt aaatcaaatc attttaaaga tgtaaagata
    28621 tattatttcc ataactgtat ttatgataga ttatttacaa cacctgaatg ttggttaagt
    28681 aaatctatta atactgaatg gatattaaaa aatatagata aaaactataa agttataatt
    28741 gttggagatg cttctatgtc gccttctgag ttgcttcata ttggtggtaa ctatcgtggt
    28801 ccatataatt atacacctgg tatagagtgg cttaaaaggt ttaagagaaa gtacagtaaa
    28861 attgtatgga tgaatccaga acttagagat ggatgggatt caattagtta ttggtatcaa
    28921 actcaaagaa tgatacaaag tgaatttaat atgtttccat tgactgtaaa aggtcttgag
    28981 aaagcattga aaaatttaat ggtttcaaga taaagtaaat ataaatgatg gtatgattta
    29041 ttcaaaattg taccatcatt atttattttt ttaatatatc tattataaat tgtataactg
    29101 aaacttaaaa aattatatag tctaatacat tttagactca cacaaaacat atacattaat
    29161 aataatttta gaagtcgagg tgattataat aaattatgaa ttaattgtaa aatacaatgg
    29221 agatatattg aggttagaag aagaattagg tgtatcagta gagatactta attcatcata
    29281 tgcaataata acatcaagta atgaagaaga tgtaaatata cttttaactt atccagaaat
    29341 tgaatttata gaaaagcctt ttatattaca gactcaggat gtgcaaagtt tttcaagtac
    29401 aggaataaca ggatttaaaa atagaactgg tttaactgga aaaggaacta taattggtat
    29461 aattgattcg ggaatagatt atactctacc tgtgtttaga gatagtgatg gaaggtctaa
    29521 gatattatat tattgggacc aatctattca aggaaatcca ccagaaggtt ttagagaagg
    29581 aacattatat actaatgaag atataaataa tgcaatagat ggaagtatgt atatacctat
    29641 ttcaacaact agcttacatg gaacacatgt tgcaggtatt tgtgcaacta ttgcaagtga
    29701 tgccagaata atagtggtta gagttggaaa tatacagacc gatatttttt cgagaagtac
    29761 agagtttatg agggcaatta aatttatttt agatagggca ttagaattaa gaatgcctgt
    29821 tacattaaat ataagttatg gaagtaatga aggttcacat agaggaacat ctttatttga
    29881 acaatatata gatgatatgt gtttattttg gaaaaacaat atagttgtag cagctggaaa
    29941 taatgcagat aaaggaggtc ataaaaggat taggcttcaa aataatatta cagaagaagt
    30001 tgagtttata gttggggaag gagagcgtat attaaacata aatatatggc cagattttgt
    30061 tgatgatttt agtgtacatt tggtaaaccc atcaaataat caaacacaag caatctctct
    30121 aacttcaggt gagataagga atactttggg tgaaactaga ataactggtt atttttaccc
    30181 tatagcaccg tattctctca caagaagagt tactctacaa ttaagttcaa atacacagat
    30241 aactcctggg ttatggaaaa ttgtatttga accaatagat atagtaactg gtaatgtaaa
    30301 tatatatttg ccaacttctg aaggtctaaa tagaaatact agatttctga ttcctactca
    30361 agagcttact gtaacagttc ctggaacagc aagtagagtt ataacagtag gtagttttaa
    30421 ttcaagaaca gatatagtat ctatattttc tggtgaagga gatacacaat taggtgtttt
    30481 taaacctgat ttattagctc caggtgaaga tatagtatct tttttaccag gaggtacaag
    30541 tggagcatta actggaacta gcatggctac acctcatgtt acaggggttt gttcattgtt
    30601 tatggaatgg ggaattgtaa atggaaatga tttatttttg tattcacaga aattaagggc
    30661 attacttcta aagggagcaa ggagattaag taatcaatct tatccaaata attcatcagg
    30721 atttggtttt ttaaatttat cagatataga tttgtacact ctatctaata taaatcaaga
    30781 tttagaaaca gaggatattg gatatagaag tattaataag tcatttaaag atgaggaaaa
    30841 tagttataag tttatagatg gttataatat gcaaatacat aatgacttag agaatgaaat
    30901 ttatataagt aaaaatgcaa gtagacaatc aggaatacta tcaggaatag atatagtcca
    30961 tactcctgaa tttgaagaag aactagctgg gttaggtatg agtcaaaggt tttttaagat
    31021 aagtgattca ttaggtgtac tatctataaa taatacagac tataatagca tacaacgagt
    31081 tttgcaactt ccttcaatca taagaactgt atcgactaca aagatgacat tacttggaga
    31141 aattaatcga ggtacttttg gaggtgtagt tgcaacagaa gaaatgggcg taaatttctt
    31201 taaaaataat cctaatatta atataacagg aagagggact ctaatatcaa ttgcagatac
    31261 aggaatagac tatctacacc cagattttat ttatccagat ggcacttcaa aaatagtata
    31321 tttatgggac caaacaaaag aaggaactcc tcctgatggt ttttatattg ggacagaata
    31381 tacacgagaa gatataaatc gagctatcgc agaaaatgac cctagtctat ctcaggatga
    31441 agttggtcaa ggaactatgt tgagtgggat atgtgcaggg cttggaaatg taaatagtga
    31501 atatgcaggt atagcagaag attctgagct aataataata aaactcggca agatagatga
    31561 tttttataat agtgcaatgt tgtttgctgc atctcagtat gcatataaaa aagcttttga
    31621 acttggaaga ccattagtta taaatatgtc tttaggtacc agtagcctag caggtttaac
    31681 caataggagt aatagtgaaa aagcgttctt tactagaggg ttatgtataa cggcaggagc
    31741 aggaaatgag ggcaatacac agacacatac atctggaata ataccatatg ttggaggttc
    31801 tgttgaagtt gaattagagt taaatgaaga cgaggaagaa ttatcattag aactttggtt
    31861 aaatagacca gataaagctg atgtaataat agtatctccc actggtgaag aaagtaaaag
    31921 tgttggaatt tcaaattata ataaagtaac aggtttattt gatttagagg ggactgaata
    31981 ttctataaca tatatatacc caacaacttt ttctggacag caatttacta atgttacttt
    32041 aaagaatgca aaaagaggtg tatggaagat tcgattagta ggagtttata ttataacagg
    32101 aagatataac ttatacctta caaatagaga acttttaaaa agtggaacta gatttagaga
    32161 ggtagaccct ttttacacta taaattatcc tgcgattcaa gatgatttaa taaccatagg
    32221 agcctacaat accattaatg gtagtttatg gcaaagttca tcaagagggc caactattga
    32281 agacaggtta aaaccagata tagtagcacc aggtgtcaat ataatagctg cttatcctgg
    32341 gaacacgtat gcaactataa ctggtacagc agcagcaagt gcacatgcag ctggtgctgc
    32401 tgcaatgtat tttcaatata cttttgttga cggtagatat ccaaaccaag catatgtgca
    32461 aaaaataaaa acttttatgc aagctggtgc tagaaaagat tcaaacacag tatatccaaa
    32521 tacaaattct ggatatgggc tcttggatgt tagaggaatg tttgatgttt taagatagga
    32581 gggatttatg gaaaaatctt attgtataat ttatcaaggt gatatagaat ctgccctaca
    32641 agaaaatgga ataaataggt atatggtttt aaatagtcag cttgcagtaa tatatgtacc
    32701 tttagatttt gatgaaacta ttttaaataa tataatacaa gttgcttggt gggaagaatc
    32761 tgaaccaatg agcagtctaa ttgaaataac taataatgta aataatggag aaaccattac
    32821 aacagcagct gaaactgatt atatttatga aaatccatat aatgatataa cagggagagg
    32881 aattttatta gcagttatag attctgggat agattatttg catcctgatt ttataaatga
    32941 tgatggaact agtaaagttt tatatttatg ggaccaagaa gcaaatacaa atccacctcc
    33001 agaaggtttt atttttggaa gtgaatttac aagaagtgag ttaaatatag ccataaatag
    33061 aaatgatggg agtttgagtc aagataatat aggtactgga actttagttt ctggtatatt
    33121 agttggaaat ggaaggataa attctcagta cagaggtatt actacagaat cagacttaat
    33181 agtagttaaa ttaaaatcat atacagatac ttattatgct ggaaggataa attacagtgt
    33241 ttcagatttt ttagcagcta taacgtatgt tactaacata gcaagaacag aaaataaacc
    33301 actgataata aatttgacta ttggagttaa gtcaagtgct gtagcaacta cttcaatact
    33361 agatactttt aatatattga gtagtgctgg tgtggtagta gtgagtggtg caggaaatca
    33421 agggaataca gatattcatt attctggcag atttagcagt gtgggagaag ttcaagatgt
    33481 aataatacaa gatggagatg actatgctct tgatataaca ctaaatacga atggtccaga
    33541 taaagtggga gcacagataa tatctccttc aggtgaagtt agtcatgata taaggtattc
    33601 tccagacttt tatatatata gaggaaaatt taacttagaa aatactactt atgcaatgag
    33661 atttatttat ccatatatta cctctggaaa agaaaatttg gagataagat taagagatat
    33721 aaaacctgga gtatggattt taagattgac ttcagaactt ataataaatg gagaatatga
    33781 catatacttg ccaaataaaa atttgatagc tccagacaca aggtttttag agcctgattc
    33841 agtagctact ataactatgt atgctgctag tgatgatgta attacagttg gtacatttaa
    33901 caataagact gatagtatgt ggattggttc ttcgaaagga ccaattagag gaagaggaat
    33961 taagccagat atagtagctt caggtgtaga tataatatcc acatataaaa atggaacata
    34021 taatacagga acaggaacag gagtgagcag ttctatagtc acaggtgttt tagccttatt
    34081 gatggaatac ttagaaaaac aggataatgt accgagatta tcattgttta cacaagtttt
    34141 aaaaacatat ttaatattgg gtgctacaaa acttgagata tatacatatc caaatgtatc
    34201 gcagggatat gggattttaa atttaaaaaa tacgattcaa cagatagcaa atactctata
    34261 gataagaacc tatgtaaaat tataattgat tattagttta attgtatcaa atactttaga
    34321 tagagtagaa aaatagcata aaaaataaat atgaaaatta aaaaacagtt ttatattttg
    34381 aatacacaaa gtaaatattt tgtatataaa taggtataaa ttaagtattg aaaagatatt
    34441 atgttaattt aaaaataatt ataatttaga cttatgaatt ttatttgtaa aattgctaaa
    34501 actattacaa aataaataat agaggtgata gttttggaaa gtaaaaaggc aagagcatta
    34561 aaaggtaaag ataataaaag acttaaaagt tcacttttag ttggaaatga gtcgacagca
    34621 gcatgggctg atgttgaaaa attaaaacct catagtaaag tttcaatacc ttcaattaag
    34681 ggtgtcgaag aagcaaaaga ctgggttgac aatggaagta aattataaaa ttttggaaat
    34741 tgaagtaata aagaagtaat gaagataagt atttattatc attatgtaag gtagaattat
    34801 tatattttaa ataacaatca gtatcaatta tataaattta ttgactaaaa atttataaat
    34861 tggtataatt ttgttaatta gcagaaataa taaaagataa atactgtgaa gagaagagta
    34921 gatataaaat gtagttctag cgagttgagg atggtgaaag ctcaatacga ggtttatatt
    34981 gaagaacatc ttggagtttc taatcgaaag cttatttagt aagtagactt agacggaagg
    35041 caccgttata ggctttaagc attgcttaac taagaggtca ttatgacaac tagggtggta
    35101 ccgcgagagt aatagtcttt cgtcccttta tatagggatg aagggctttt tttattgaaa
    35161 ttatatttaa aagaaattaa taacaattat actaggagga tttaaaatgc aaaaggaatt
    35221 tataacagta aaagaattgt acagagaaaa agaacagtac atagggaaga ctgtaaaagt
    35281 agctggatgg ataagaacat ctagagtatc taaaaatttt ggatttatag agctaaatga
    35341 tggaagcttc tttaaaaata tgcagatagt atttgatgag aaagtagaaa attttaaaga
    35401 ggtaggaaaa ttagcaataa gctcatctat acttgtagag ggagagttag tatctacaga
    35461 aggggctaaa caaccagtcg aaatacatgc aaaaagcata gttgtagaag gggaatcaga
    35521 tagttcgtat ccactacaaa agaagagaca tacgcttgaa tatttaagaa cgatagcaca
    35581 tttaagacca agaagtaata ctttttcagc tgtatttaga gtaagatcaa tagctgccta
    35641 tgcaatacac aaattcttcc aagaaagaaa ctttgtatat gcacattctc caatcataac
    35701 aggtagtgac tgtgaaggtg caggagagat gtttagaata acaactatgg atttaaatga
    35761 tattccaaaa actgaagatg gcaaaataga ctatactcaa gatttctttg gaaaagaggc
    35821 taatttaaca gttagtggtc aattaaatgc cgagataatg gcactttctt ttagaaacgt
    35881 ttatactttt ggacctacat ttagagctga aaactcttat acaggaagac atgcttcaga
    35941 attttggatg atagagccag aaatagtttt tgcagacctt gaagataaca tggaacttgc
    36001 agaagatatg ataaaatatg ttataagcta tgtattagaa aatgctcctg aagaaatgga
    36061 attttttaat agttttatag ataaaggatt gttagaaaga ttaaataaga tagtaaactc
    36121 tgagtttatt agaataacgt atactaaagc agtggaatta ttaattgaat ctgggcatga
    36181 atttgagtat cctgttgagt ggggatgtga ccttcaaaca gagcatgaaa gatatataac
    36241 ggagcaaata tataattgtc cagtgtttgt tacagattat ccaaaagata taaaagcttt
    36301 ctatatgaga atgaatgaag atggtaaaac tgttagagca atggatttac tagttcctgg
    36361 agttggagaa atcgtaggag gttctcaaag agaagaaaga gaagatgtat tgttagatag
    36421 aattaatgaa atgggattaa gagaagaaga ttattggtgg tatttagaac ttagaaagtt
    36481 tggtactgct actcactctg gatttggtct tggatttgaa agaataatta tgtatatgac
    36541 aggtatgtct aacataagag acgttatacc tttcccaaga actcctaaaa atgctgaatt
    36601 ttaataatta tatataataa aacttatata actttaagta taaacactaa aatgacttgc
    36661 atatttatct attttagaga tatgcaagtt atttttattg tactataaat atataatttg
    36721 attactttta ttttgcgata taatacttat aggtttatgt aatagtatgt aaccttttaa
    36781 taaaatgcaa cacaattacg tccttgttct tttgcagtat atagggcctt atcacaatta
    36841 cttataaact catttaatgt tattgtcttt ccaattttct ttgtataaac tccaatacta
    36901 acagttacac attttaaagg aacatcatca cgctcaaaat tgcaggactc tataattttt
    36961 cgtaaacatt ctgatttaag tttagcatct gcctcattac agttaaaaat acatataaaa
    37021 aattcctcac caccatatcg tatagcatgt tcattttcag aacttgtaaa atctaaaatt
    37081 actttggcaa tattttgtag acaatagtct cccttttgat gtccataatt atcattaaat
    37141 tgtttaaaat aatctatatc tatcatcatt ccagttatag gttcttgatt tgcatggctg
    37201 attaattttt tttgtagaat atcttcaagg tacctacggt tgttcatttt agtaaggtca
    37261 tctgtcataa ctttgtcgtt aagtaaatta tttatatgag atatttcttc atattgttga
    37321 ctaattaaaa gtttatcata gtaagtaaat acacgatttc tatatagcat tgtagaaaca
    37381 aaaatggcaa gggatgttat aaaaaatgtg ttgacaatat tactaaactc attgcctggt
    37441 atagtttgaa tcccaggtaa gaataaatta agaaacaaaa agcatcctcc aaaaactatt
    37501 actgattctc caaattttaa tactgagaaa gctgcagctg ctaacataat ataactaaat
    37561 acacttaggt catttccacc taactggtca agtagagtaa ttacacaacc ccataggcag
    37621 aaaaaagtca cataaattat ccataaattt atataaaacg tacagcaatc ctttttttta
    37681 ttccaaaggt aagaaaatac aaacataaag acagaagata cacaaaatag tgttacatac
    37741 atataaaaat accattggcg tcttggtgtg acaaaagggc ctccttctct agctgagatt
    37801 gatatcatca taattatttg agatattact attattatgc aaatgatttt acccgtatga
    37861 taaagataat tgcagagttc tttctcaaca ttgtctttgt gttttttgtc tagaggaaat
    37921 ccaaaaaatt tttttatttt ttctaagttc atataagcct ccattaaaaa taaagcataa
    37981 aaataagtat tcctttctat cattagatat ttggaatact tcgtttatga tttaattata
    38041 tcaaaatata ttgtgtgtaa caatctaaaa ttgtgataga taaaatttat tagataatgt
    38101 cgagtaactt tattgattaa tactttatta taattaagat ttacagatag tttactactg
    38161 aaaataaaga atagaataaa tttaaattaa gcataataaa atataaataa taaagttcgc
    38221 attaacaaac tatttaaata tcaagacctg ttaaaaaaca acagcaataa acaaataaaa
    38281 tagataaata tatccaatta aggtataatt aagttttata tgatatagtt atatttgata
    38341 atttacaata gtaaaacttg gagggaaaaa atgggtgaaa agaaaataaa taatatgaat
    38401 tattcacata ataattattc caaaaagaca ggtgaaccaa ctagaaaaat aaaaaatagc
    38461 catatcactc ttaaaagtaa agaagaaaaa atttgttcta gttgcaataa agaaaataat
    38521 actaaggata attactgtaa attttgtgga aatgaacttt atgaaatagc atcattaaga
    38581 ccacttgaaa caaaactaga cttgaaatct aaaataaaag agctttcata tcatgcaaat
    38641 aaaagaggtg tatttttaac aacatttaca accatattta tattgtttat tattgcattg
    38701 atatttaaag ctattataac tattcaattt aatgatatta gttatttaat aaatccagca
    38761 catataatcc tagctctcaa cttgggtcaa attagtgtat ctatgtctac catgatgggt
    38821 tctgggttta taaatgccaa tataggtttg ttgatattac ttataatccc tattttggta
    38881 ttattaatat caaacctaat ttttatgaga aaaagatgta gagattcaaa aactgtatta
    38941 gcaaattctc taggagttgg aattttttat ggattagttt tagctatttt atctattttt
    39001 actaatgtaa aaactagttc acatagtatg ttagaatatg gatatgcatt agaatatagt
    39061 tatgaatttt ttagtgttct tttaaatgga tttgtattag ggtttatatg tacatacata
    39121 actacttata aaaaaagtta tgaaaaggaa aatatgtatt tatctctttt ttcaaattct
    39181 ataagaacat tcatattagg ttatgtttta gtattagtaa tactattggt actaactata
    39241 tctgatagta gttacttaaa tgaactagat atgagtagtt attcaaatgg attaaattta
    39301 tttactatac tcccacaaat agctagttat atgtgggctt ttgcaaatgg aatttcagta
    39361 accataataa actcaacagt atcaatgttt actttaagtt cttcatcttt atttggagat
    39421 actaaattaa tgttttatgc aatgggagca ttgtctatgt taatattatt attaaatgga
    39481 tacaagctaa gatttaagta taatacagat agtataagac ctataatagt atttagtata
    39541 tattatgcat ttttgatggg aatattggct ttatttagta catttatact agatagtaat
    39601 attaatttct ttaatacaac taattatgga acaactttaa taatgcaatt taaagtctta
    39661 caagctattg taatttcatt tgtatatagt tttgtgatat ctttaatagg atataagcta
    39721 aattcagctg attaaatatg attggaggga atttctgtgg aaggaaatac taataataaa
    39781 gtagatgata aattttctaa ggttaagaaa aagtttggta gtggaaaatt taaagttgaa
    39841 ttatataaag aaaaatcaaa attaaataga gagattgatg atattcaaga aaagaaagca
    39901 aagatattct tggaaatggg aatactgaca tatcaaaaaa ttagagaaga ttctattaat
    39961 gataatagtt ttgataaatt ctgtgatgag ttactagaac ttgataagtt aatttatgaa
    40021 aaaaatatgg aaattaatga aatggaaatg gcagaaagta atgtaacttg tgagtgtggt
    40081 tatgttggaa atgtaaatga taaatattgt gctgaatgtg gtaaaaaatt tgaattggaa
    40141 aatgaatgtg atgattttat aatttgtggt tattgtgaaa gtgagataga tacagaggct
    40201 gaattttgtc catgctgtgg aagaaaaatt ataatggatt tagaataata ttgggaaacc
    40261 tatgtatagt atacatgggt ttttttattg aaattattta aatggactta taacagtagt
    40321 tatataaaat gaaaataaac accaaaaaaa tgaaataaaa tttcttttaa atgtaaaaaa
    40381 caagctaata tataaaataa atcagtaaaa atatagatgc gagaaaaaaa tatgaaaaaa
    40441 tattgcaaag aaaaagtttt catgttatta ttaatacata aatcaagaaa ataaatttca
    40501 gaaacgaggt aatttaaaaa atgctagata aggtaaaggg aagattaata gtatcatgcc
    40561 aagctttaga agatgaacct cttcatagtc cttttataat ggggagaatg gctaaggctg
    40621 ctatggaagg tggagctgtt ggaattagag ctcaaggagt tgaagatatt attgaaataa
    40681 aaaaagttac tggacttcct gttataggta ttataaagag aaactatgaa gattcagata
    40741 tatatataac gccaactaaa aaagaagttg atgaactttt aacaacaggg tgtgaaatga
    40801 tagcattaga tgctaccaat agagttagac caaataatga agacttaaaa gaacttataa
    40861 agtatataaa agaaaacggt gttctagtaa tggcagatat ttcaaattat gatgaggcta
    40921 tcaaagcaca agagtacggt gtagattgcg tttcaactac actatctgga tatactccat
    40981 atactaaaac attagaaggt ccagattttg tattaatgga aagattagtt aaagatttag
    41041 aaatacctgt aatagctgaa ggaaaggtaa atactcctca agatttaaaa aaggtctttg
    41101 agttgggtgt tcattcatca gtagtaggtt cagcaataac aagaccacaa ttaataacag
    41161 aaaaatttgt taaagcaatt gaaattaatt aaaaattaat ttataaatta aaaaattatt
    41221 atatttaact atatttgaaa attaaaattg gaggtaaaga tatgagaaca acagatatga
    41281 agggaattta ttcagcatta ttagtttcat ttgataagga aggaaatata aatgaaaaag
    41341 ggttaagaca aataattaga cacaatatag atgtttgtaa agtagatggt ctttatgtag
    41401 gaggaagtac aggggaaaac ttcatgcttt caactgatga aaagaaaaga atatttgaaa
    41461 tagctaaaga tgaagtgaaa gaagaaataa aattaatagc tcaagttggt tcagttaatt
    41521 taaaagaagc tgtagaactt gctaaattta caactgattt aggatatgat gcaataagtg
    41581 ctgttacacc tttttactat aaatttgatt ttgaagaaat aaaacactat tataatacaa
    41641 taataaattc tgtagataat agattaataa tatactctat accattttta actggtgttg
    41701 atatgagttt agaccagttt ggagaattat ttgaaaatga aaaaataata ggtgttaagt
    41761 ttacagcagc agatttctac ttattagaga gaatgagaaa aacattccca aataaattaa
    41821 tatttgcagg atttgatgaa atgatgttac cagctacagt tttaggtgta gatggggcaa
    41881 ttggttctac attcaatgta aacggtgtca gagctagaca aatattcgaa ttaactaaga
    41941 atgaaaaaat atcagaagca cttgaagtac aacatgtgac taatgattta ataacagata
    42001 tattaggaaa tggcttatat caaacaatta aattactact tgaagaacaa ggtgttgagg
    42061 ctggatactg tagacaacct atgaaagaag caactgatga aatgaaatca agagcaaaag
    42121 aaatatacag aaagtatttt taataaaata cttttagtat gggaggatta gtcaaatggt
    42181 aggatttact tggatagatt ttgcaatact agtggtttac ttattggcag ttttatttgc
    42241 aggattgtta ttttcaaaaa aggaaatgaa gggaaaagag ttcttcaaag gtgatggaac
    42301 tattccgtgg tgggttacat cagtatcaat atttgccaca ttattaagtc caatatcatt
    42361 tttatcatta gcaggaaatt cttatggtgg tacttggatt ttgtggtttg cacaattagg
    42421 tatgtttata gcaatacctt tgacaataaa atttttctta cctctatata gtaggttaga
    42481 aatagataca gcatatgaat acttagaaat gagatacgaa agcaaaggtc ttagagtact
    42541 tggagctttg atgtttataa tatatcaaat aggacgtatg tctatcataa tgtatcttcc
    42601 atcaatagtt ctggctggtc ttacaggaat acctgtaaat gtactgataa tagttatggg
    42661 tgtaatagca ataatttact catatacagg tggattaaag gctgtcttgt ggaccgattt
    42721 tatacaagga atggtattaa tagtaggtgt tacagggaca ttgttctatt taatagcaag
    42781 tataaatggt ggttttggaa cagtaatgga tactcttaca actggacaca agttcttagc
    42841 aagtaatgaa gttatgtttg ataaaaatat actatctaca agtgcattta taatatttgt
    42901 tggagctggt cttaatactt tttcatcata tgtatcgagt caagacatag ttcaaagatt
    42961 tactacaaca actgatataa agcaacttaa taaaatgaca tatggaaatg gtgttttatc
    43021 aatgggactt gcaacagtat tttatctaat tggaacttgt ttatttatat actatactca
    43081 aaacccagat ttagctcaaa cagttcaaca agaccaagta tttgcatcat atatagctta
    43141 tgaattacca gtgggtataa caggaatact acttgcagcg atatatgcag cttctcaatc
    43201 aactttatcg acagggctta attcagttgc tacaagttgg actttagata tacaaactat
    43261 cataacaaaa gatataagta tggaaaagca aactaagata gcacaatata tatcattagg
    43321 tgtaggtata ctttctatag ctgttgcaat agtattagca aatggagaaa taaagtcagc
    43381 atatgaatgg tttaatagtt ttatggggct agtactaggt gttttagcag gaatatttgt
    43441 acttggtgca ttttgtaaaa aagcgactaa aatgggagca tatgttggat tcatagtatc
    43501 agcaatttta gttgtttatt taaaataccg tatgccagaa gtaacttctt gggcatattc
    43561 tctaataaca atcacgactt ctgtagtggt aggtacaata gttagtgcaa tagaagctaa
    43621 agttaaagca aaagtatctt taccaaaagc tgagactact gtttattatg aaaaataata
    43681 tttaaatgat aaattgtctt atagagtgat tagataaata atttagttac tctataagat
    43741 tgtataatat actttgtata taaaagtata aaaatagact ttataattat atagggagat
    43801 agtgcttatg atatttggaa atataaatca tagtaagaca tattcaacat tgcatgaaga
    43861 tttacttaga tgttttgaat atgctaaaga taattcatta atagattatg aaaaaggtac
    43921 ttatacaata gatggtgatg atatttttgt gaatattgta gagtataaaa cttgtgaaaa
    43981 agaagataga ttctgggaag ctcataagaa gtatatagat gttcatttga tgcttgatgg
    44041 atgtgaacga atagatataa attttataga aaatttagaa caaaaaatat atgaagaaaa
    44101 gggcgatttc ttgcctcttg atggtaaaaa taatggatac atggaactta gaaaaggtga
    44161 ttttttagtt tgttatccgg aagatgctca tatgacagga ataaaagttt tagaaaaaga
    44221 aaatatcaaa aaagctattt ttaaggtttt ggttagataa tgataattta tataaccact
    44281 agggctgaaa atagtgattt aactttcagc gattagtgag acttcgtaaa ttttagttag
    44341 attactattt tcagccttag ttttttatga gaaaattgaa aataattaaa agcttaaaat
    44401 tttgtaaagg agttaactta tggaaaatat agatgtattc ttattaatag gacaaagcaa
    44461 tgctagagga ttgggaaatc caaaagagag catcattcca aatgaaaatt gttttgaata
    44521 tttgagtact gatgaaatta taaatatgag atgtgagcta gagacttcag aaggtgatgg
    44581 tactatagca cctgcatttt caaatgaatg gaataagctt actggaaata aagtttgttt
    44641 tattcacaat gcaaaagatg gttcaagaat aaaaaactgg aatcatgata ataactggtt
    44701 tctaaatgac actatagaaa aatttaatac aggctgtact accttaagta aacattataa
    44761 tatagaaaat aaatacgtta tttggattca aggtgaaagt gatgcaaaat atggtagtga
    44821 tgtattgtac tataaagaaa gtctaaaaaa aattgcgtat aggcttaaag aagaatgtat
    44881 gattgataaa atgtttgtaa gtttaactgg ttattggctt ggagaagatg aatattttat
    44941 tagaacaaga cgaattgcag cagcacagga gtcggcttgt agtgaatgtg atatattatg
    45001 tgtaggaagc aaaattgcta tgcagtttca tgacagagga ttaactattg atgatgttca
    45061 ttacactcaa gaaggtctta atatgttagg agaggactta tgtaaaaata tttataagta
    45121 tcatataacc aaagaaaaaa gtgtattaag tgatactata gacttatcag aagcaaggaa
    45181 atatatctgt gaattggaaa agataagtaa aagatttgtg taatataaaa ttttaaatag
    45241 agttgttaat ttataaaaat aatttgtatg gagatatgtt atgaaaaatt acgtttgtat
    45301 agatgttggg ggtacttcaa taaaatatgg ttttattaga gaagatggat ttataattga
    45361 taaatcaagt cttgatactg aagcaaagga aaaaggtgga gaaggaatat tagccaaaat
    45421 aaaagatata gtaaaaaaat atatagagga aaatgaaata agtggtatat gtatatcaac
    45481 tgcaggtatg gttgacccag ttgaaggtaa aatactattt gcattagaag aattaattcc
    45541 aaactataag ggcatgcaat taaaaaaaga agtagaaaaa gagtttaata taaaatgtga
    45601 agttgaaaat gatgttaatt gtgctggact tggtgaaatg tggcttggag caggtaaaga
    45661 tgcaacatct tctatatgtt taacaatagg tactggaatt ggtggatgta ttataataaa
    45721 taataaactg ataaatgggt ttagtaatag tgctggtgaa gtaggatata tgaatgtaaa
    45781 tggaagttct tttcaagaat tggcatctac tagcagtcta attaaaaaag tagcaaaaat
    45841 aaaaaatttg aatgaaaatg acttaaatgg aaaaataatt tttgatttag caaagaataa
    45901 tgatgaagat tgtttaaaag aactcgataa tatgataaaa tcattagcag ttggaatcgc
    45961 aaatatatgt tatgtaataa atccagaagt ggtaatttta ggtggtggga ttatggcaca
    46021 agaaaagttc ctaaaaccaa aaatagacaa agcattaaag gaggttctta tagagagagt
    46081 ttacaaaaac actaatatag aatttgcaaa gagacaaaat gatgcaggaa tgcttggagc
    46141 attatataat tttttaaaca aaatataaag aatagaaggg tttttaatga gtattttaga
    46201 acaattggaa tcaccaactt ttaaagtcac aaaatcagat aaattattaa tagcttatat
    46261 aaaagaaaat atagatgatg tattttataa accaatatca caaatagcta aagagagcaa
    46321 tattggtgaa gcaactataa ctaggtttgt aaaaaaaatg aattttaatg gattacagga
    46381 ttttaaagtt actttagcac aagaaatatc aactatcaat aaaaaaaata ttataaataa
    46441 aaatatacaa aatgatgagc cagctttgga tacagcaaaa aaacttttaa gttcaaatgt
    46501 aaccacttta gagaacacag tagagataat caatagtaag gatgtacatg actgcgcaag
    46561 gcttataata aatgcaaaga aagtttactt cataggtatt ggatattctg gtataatagc
    46621 acaggattca aactataaat ttatgagaat aggtcttaat tgtgtaagtt ttgacagtag
    46681 tcatacaatg ataatgatgt cttccataat ggaagaagga gatttaataa ttgcaatttc
    46741 acattctggt gaaacagaag agattataaa aactgtaaag cttgcaagag ccaataatgc
    46801 taaaattata tcaattactg aaaataaaaa ttctgaatta aaggatattt cagatgtaca
    46861 cttatcttat gtatcgggag aaacagtact ggaaactggt tcaatatctt ctaaattagc
    46921 acaatttttc attattgatt tagtatatac acaggtagta aaagaacttt ctaatgaagc
    46981 tattgaaagg aaaattaaaa ctacaaatgc tataaaattg tttaaaaatg aataaaataa
    47041 gaaatttgta atgttttata gagctctctt aaaaatttag gaatggagag atattacatg
    47101 tctaaattaa aagattataa tattgataaa gtaataattt ttaataattt aagtactaaa
    47161 acgaagaatc aacttaaaga aaaagttaaa ctaaaaagat tacaaaaaaa agaaatttta
    47221 ttttatgaaa aagatagctt agacagtgtt tatatacttt tagaaggaaa ggtatctatt
    47281 tttaagataa gtgaaaatgg agagagaaaa gtaattttca tattaaatag tggggaagtc
    47341 ataaatgata ttacacttga cgcttctaaa aactctactg ttggctgtga agcatttgaa
    47401 aattcaattg tagcttatta tagtattgaa gaatttttag aaattatgca aaatgatttt
    47461 caacttacaa aggatattat ttcttatatg gaaagaagaa taagacgttt atatagacag
    47521 ttgaaaaatt ctatatccat aaaagtagat aaaaaacttg cagcaaaatt atataggtta
    47581 agtagagaat ttggagtttg ctgtggagaa tggactttac taaatgtaaa tattacagtt
    47641 acatatttag ctgatatgct tggctgtaaa agggagactg tttccagaat gataaaggta
    47701 ttgcaaaaag aagaacttat taaaattgac aataaaggtt tttatgttaa agaaactgaa
    47761 ttatcaaggt attttaaaaa taattaatta tgattaagta agagtattat tagaatttta
    47821 attaaataaa aatattatta agagaatcta tttatagatt cttttttatt gtctaattta
    47881 ttaattttta ttttacccta ttgaattgta taaaaaaaca aataagattc ttttttattc
    47941 aaaaaattga gtagatagta gttttattgt acttaatgat tgtatttaag tgattagatt
    48001 tgaaatcgaa taatgtagat aataaaaaaa tattaacaga acttaataaa ctccattaat
    48061 atttttttta ttatttttga aactgtgata attatcacgg aagcatagaa aataaagtgt
    48121 taagatttaa acaagatagc aagtaagtaa aactaaaata taagaaaggt gataaaaatg
    48181 aaactaaaat tagattcatc taagttcaat gaaggtctga attatctaaa aaaagactac
    48241 aagatatttg caccagtttt aatcccattt aaaggtactt tttcagatac tgatgttata
    48301 agatacaagg aggtaaacgc ttttgaagaa atggaatttg ctaagaaagc aaacttttca
    48361 ccaaaagaag ttgtacttcc cataaatcaa gtattgtttt attttactga aaaagagttt
    48421 aaggaaagcg atttagacaa caagaaaatt ttaattttct taagagcttg tgacataaat
    48481 ggtataaaaa gacttgatga aatatatcta aataatggtg aagaaaaaga ttatttttat
    48541 aaaaatatca gagataaagt aaagtttgca cttgtagggt gtaaggaaag ttttagaaac
    48601 tgtttttgtg tgagcatgga ttctaacaaa actgataatt attcaattgg attaaatata
    48661 gaaggagata cactgtactt agatataaag gatagtgaat ttgaagtatt taatggagaa
    48721 gcaactgaat ttaatgttga ttatgtaact gataatttaa tatctgtaga tgtgccagag
    48781 aatattgatt caaatgaaat gataggaaat tcaatatggg atgaatatga tacaagatgt
    48841 ataggatgtg gtagatgtaa ttttgtatgt ccaacatgtt catgttttac aatgcaggat
    48901 attttctata aggaaaacga aaatgtaggt gagagaagaa gggtttgggc ttcttgtcaa
    48961 gtagatggat atacagatat agcaggtgga aattctttta gaaaaaaaca aggcgaaaga
    49021 atgagattta aaactatgca taaaatacat gattttaaaa aaagattcgg atatcatatg
    49081 tgtgttggct gtggaagatg tgatgatgcc tgtccgcaat acatatcatt ttcaaagtgt
    49141 atagaaaaaa taaatgattt agtaattagt aaggaggaag tataaatgaa cccatatata
    49201 ccagtaagtg caaaaatact agatatagtt aaacatactg ataaagaatg gacttttaga
    49261 gtaaactgca atacaaaagg tgtattgcct ggaaagtttt atgagatatc tatacctaaa
    49321 tacggtgaaa gtccaatatc agtatcagga tatggagagg attatattga ctttacaata
    49381 agaaatgtag gaaaagtaac tagcgagttg tttaattata aagaaggaga ttcttttttt
    49441 ataagaggtc cttatggaaa tggatttgat gtatcccttt atgaaggaag agaaattgta
    49501 gtagtggcag gaggaagtgc attagcccct gtaagaggaa tagttgaata tttttataat
    49561 aataaagaaa aatgcgaaaa gtttaaatta atagtaggat ttaaatcacc aaaagatatt
    49621 ttatttgcag atgatttaaa gagatggagt aaaaaacttg atattttagt tactgtagat
    49681 ggagcagagg aaggatatag tggtaatgta ggattagtaa caaaatacat accagaattg
    49741 gatatgaaag atataaacaa tacttctata gttgtagttg gacctccaat gatgatgaaa
    49801 tttacagtag aagaattttt aaaaagagat ttagatgaaa agaacatttg ggtttcttat
    49861 gaaagaaaaa tgtgttgtgg aataggtaaa tgtggacatt gtaaaatgga tgatacttac
    49921 atatgtttag atggaccagt atttgattat tcatatgcta aaaatcttat tgattagggg
    49981 gtgaagtttg tgataagaga tttaaatacc aaaaaagtaa tgaaaaatgc ttatagaatt
    50041 acaaaaacaa aatatgagac ttctttaaga gttagagtac ctggaggtct tattgaccct
    50101 gagagtttag ctgtagtttc taaaattgca agtgagtacg gcaatggaca ggtgcacata
    50161 actacaagac aggggtttga aatattagga ataaatatgg aagatatgga agaaataaat
    50221 aaaattatac aacctgttat tgaaaaaatg aatataaatc aaagtgagaa aaacgcaggt
    50281 tatccagcag caggtacaag aaatatagca gcttgtatag gaaataaagt ctgtccaaag
    50341 gctcaatata atacaactga atttgctaaa agaatagaaa aagctatatt tccaaatgat
    50401 ttacatttta aagtggcttt aactggttgt ccaaatgatt gtataaaagc tagaatgaat
    50461 gactttggaa ttattggtat ggctttacca atatatgaaa aggatagatg tgtaaattgt
    50521 ggagcatgtg taaaaaaatg ttctaagata tctgttggag cattaaaaac agaaaataat
    50581 aaggtggtaa gagataaaga taagtgtata ggctgtggag agtgtgtgct aaattgccca
    50641 acaaatgcat ggactagaga tgagaaaaaa tactatagat tagctataat gggtagaaca
    50701 ggaaagaaaa accctagact agcagaagat tttcttttat gggtagatga ggacagcata
    50761 ataaagataa tacttaatac ttatagatat gtagaaaagt atatagataa agatgcacca
    50821 ggaggaaaag aacatatagg atatataatt gatagaacag gatttatgga atttaaaaaa
    50881 tgggcacttg aaggtgtaga gcttccagaa ataactaaaa tgtacgaaaa catatactgg
    50941 agtggaatta aatatctata aattgagtaa aacatatatt tgaataaatt aaaatttaat
    51001 agaaggaaga gggaattatg cataaagaaa ctttggataa attaactaat gcagctataa
    51061 ataagataaa tttattaaac acaagtaaag taaaatattt ggtatcttct gcgtttgcag
    51121 gactttatgt aggtataggt atacttttga tatttactat tggaggactt ttgactgatg
    51181 caggttcacc tatgactaag atagtaatgg ggttatcatt tgcaatagca ctaagtttgg
    51241 ttataatgac gggaacagag ttatttactg gaaacaatat ggttatgtct gctggtatgt
    51301 taaataaagg tgtaagtata aaagatactt ctaaaatatg ggcatacagt tgggtaggta
    51361 atttaatcgg agctttggtt ttaggcatta tatttgtagg aactggtcta atagacaaag
    51421 gacctgtagc tgaatttttt gcaaatacag cagctagtaa agcatccatg ccatttacag
    51481 ctcttttctt tagagggatt ttatgtaata ttctagtatg tgtatcagtg ttgtgttcgt
    51541 ttagaactaa tagtgatact gcaaaaataa ttatgatatt cttatgttta tttgctttta
    51601 taacatcagg ctttgagcat agtgtagcaa atatgacaat ttatagtgtt tcattatttt
    51661 caccaacaat aaatacagtt actattggag gagctattta taatttagta gctgtaacac
    51721 ttggaaatat tgttggagga gctttattta tgggtcttgg aacttatata ttaggtaaag
    51781 aaaagcttaa ttaaatttat tgtataaatt ataactctct tgataaatgc atttttagta
    51841 ttgttgagag agttattttt atatttttga aaaaatattt gaaacaaaaa aaatatggga
    51901 gcatacgaaa atatatcggt tatatatata aaaaatacgt ttatatatga attatatagt
    51961 tctaaatata aaaaaagtta aagtcctacc gtaaaaaagc gcattttgaa taagataaca
    52021 aatatgataa aattggtctt gttgaaattt ttagggggga tatgatgaca aagaaactag
    52081 taatatcaaa aacaaagttg tttattttta taatagcatt tatttctata tttatatatt
    52141 tatttggaag taaaaataca cttataggtg taggtatagt aacagctatg ctaacgctct
    52201 tggaaagaga tttaactatt tctccaatta aaaatttact gaagtattta gcaataaata
    52261 taatcttagg aatactatca ttttttgcag tacaaaatat gtatttagga gttttattaa
    52321 attttatagc attatttata atagggtatg tatttagtta tgacttaaaa agagcagtat
    52381 atgtaccctt tggtctaatg tatatattta tggtaagtat acctgtagga aaaagtgaat
    52441 ttcctatgag attgtcggct ttagctgttg gagcagttat aataatgatt gctcaatttg
    52501 ttatgaatag aaataggatg aaaaatgtcg gagataaaga actgatatct atatgtgatg
    52561 aattattaga aaaaattagt cttttaaaaa atactattaa tgatgatagt tctataatta
    52621 aatctagtat gagaaaaata gatagctgta attatagaat aaattctata tctaaaaatt
    52681 tgaaaatggt tatttttgat aatagaaaag atgactttta tatcagtatt agaggtatag
    52741 acataatgaa tattttattt tcattagaaa gaataagttt aatcctagaa agatacaaaa
    52801 aggatagtaa agaatttgaa gatgaagata taaaaaatat tttagaagaa agtagcataa
    52861 atagtaaatc agatgttcta gttgtagcaa cgaaagaaat aaactatatt aagatgtgtt
    52921 tagaaaataa agataccata actgataaag agatattagg atttagagat tatgttattg
    52981 ctcaggatac taaaaatata aatttaaaag aaatttatag tgttttagaa aatttatatg
    53041 agtttttagt agattataaa aaagtaaaat caagagacga aaagaaagct gaaagaaaat
    53101 caaagatacc tcatgaattt aaacgactat caatatataa gaaaaacttt aatttaaatt
    53161 ctataagatt ttcttatgca gtaaagattg ctttagctac agctgtagcg ggttttatta
    53221 tggattattt ccatttaaga gatggaagat ggataatgtt aactgtcttt tcattaacac
    53281 aaccttacgc agaaaattgt atacaaaggt ctagaaaaag aatagaaggt acatttatag
    53341 gagctgtaat atttattgta ttattttcaa taataaaaga tagtacatta aggtcgttaa
    53401 tagttctttt agcagggtat ataaactctt atgtagttga ttatagaaaa ttaatggtat
    53461 gtgtaactgt ttcagctctt ggttcagcag tagttatggg agacccaaat gttttaacca
    53521 taagcaggat ttcatatgta gcattaggag caattattgc attaatagta aataagttta
    53581 tattaccata tgatgctaaa acaggctatc aacatgttat agaaatgtat aaaggaatag
    53641 ttaaaaatat aattgatgaa gtcaataagt ctatagaaaa tgtagctgat gtttactata
    53701 taaaaaattt attattgata ccatcactta ttgaagatag acttatgttg ataaatgcta
    53761 tatataaaga taaacatcaa gaggattttt tagaaaatca gaaattacta ataagtaata
    53821 tgtataatct atatataaat gttaataaaa ataaaataaa agatgaagat gttgaaaaaa
    53881 tattgagaga tactaattat atttcaaatt acaatgtaga taagtatgat gaaggaagaa
    53941 gtgtaatttt agagagtatt ataaatacta aaagtctagg tgacaagata atatgtctaa
    54001 acttactgca aactctaaat ggtgtcaaag aaatgtatag aataagtaat ataactaaag
    54061 tttcaataaa agaagcagct tagatattaa attatagaat agccatatat ttaaaataaa
    54121 gtatatggct atttgtttta taaaatacta aaagaaaata atatataaaa aacaaaaaac
    54181 atatatttat gaattttata tgaaaatagt taaaatattg atttttttca ttggttgaaa
    54241 aaacaattta cttaggataa actataatag tattcaaata ttatgggggt tagatttatg
    54301 agtaaagatg taaaggtaaa gcgtaataag aaatatgata catttagtat aactatggaa
    54361 cttgagagac ctttacttta tgatgaggtt gagaacaaag atgataaaaa taataataga
    54421 aaatttaaca taaagaataa gatatttaag ggaataggta tactatttgt attgattttg
    54481 cttggctttt tcatatggat aaataaaaca tatgaacctc aaaagctggc aaaagaagct
    54541 ctagtcagca atagtaaagt tgaagtaact gtaaatgaaa acatttcatt tacaccaaaa
    54601 ggaagaaaag tttctaaagg tttaattttg tatccaggag ctaaagtaga aatagaatct
    54661 tatgctccac ttgcaagaaa aatagcagaa agtggatatg aagttgtaat cgtaaagatg
    54721 ccacttaatc tagctatact tggaactaat aaggcacaga aagttatgga ttcttacaac
    54781 aacatagaac attgggtaat aggaggtcat tcattaggag gagttgcagc atcaaatttt
    54841 gcacgtgata ataaattaat tgaaggcgtt gtatttttag cttcttatcc aatgggtgat
    54901 gagttgaaag aattaggaaa aaaagttata tctatatggg ggagcaaaga tggagtagtc
    54961 aattttaaaa gtcttgtaga atcaaaacaa aaacttcctg atgatacaac ttatgttgag
    55021 attgaaggag gaaatcatgc acaatttgga gattatggaa aacaaaaggg agataatgat
    55081 gctattataa gtcaagaaaa acaacttaat attactgcca atagtatcat taaattttta
    55141 aagaatatat cttaaactaa aatttaaaaa atataatttt ataagttatt atttaaagta
    55201 aatattaata atataataga atgaatattt tattacaagg gggattttaa tatggaatac
    55261 gatatgccac tttacagacc accaagtgag gcttatagtc ttataataca agtcacacta
    55321 ggatgttctc ataacaaatg tacgttttgt agtatgtaca aatctaaaaa atttaaaata
    55381 aagccactag aagtaataaa aaatgaaatt gatatattta gaagatatta taagcatgta
    55441 gaaagaatat tcttagcaga tggagatgca ttgataatac caatggagaa attaagagat
    55501 attattttat atataaaaga agtttttcca gagtgtgaaa gaattactat gtacggctct
    55561 cctaaatcta tagagaaaaa atctgatgat gaacttaaag aattaagaaa acttggtgtt
    55621 aaaatgattt atctagggct tgaaagtgga agcaatgaag tattagaaga tattaagaaa
    55681 ggttttagta gtgaacaatt aataaaagtt ggtagaaaag ttaaaaaaag tgggattaaa
    55741 ttatcagcca ctgtaatagc aggtcttgga ggaactaaaa aaacacatca gcatgcagtt
    55801 gatacaggaa aaatgctagg agcaatttca ccagattatg tgggtgtact tagtttaatg
    55861 gtagaaccta atactgaact ttacgattta cttaaggcag gagagtttac aatactagag
    55921 gataaggctg tgttacaaga aattaaagag atgataaaga atatagatgc taatgaaaaa
    55981 attgtattta gaagtaatca tgcatcaaat tatgctaatt taaaaggtgt attacctgat
    56041 gataaacaac gtctaattga tgaaattgat tactatctaa gtaaccaaaa gctaaaaaga
    56101 gaagaatata gaagactata gtttttgata tatcaatcta tactgatagg taaatactaa
    56161 gattatttag atacaaaaaa tcatgctaca ttaatagttg cttactattg atgtagcatg
    56221 attttttatt aaaaaacaaa atggtatatt catatataat atatcaataa taatgaaaat
    56281 gtgaactagt ttaatagaat tttacctatt ataataaaaa caggaattta aataataaaa
    56341 agtaaagtaa ctttttatta agtaacttta ctttttattt tatttaatgt tgtattaaat
    56401 ttatatatat taaaataata tacaaatttt gaaaaagctc ttataaaatg attattaaag
    56461 taaagtttaa tataaataaa ttataaaata ttaaactaat ttatcaatat ttcctgattg
    56521 aatatgctta atgtttgatt gaattttttt atatggccaa tcccaccatt taatttctaa
    56581 taattttgaa attgtatcat tattaaatct cttttttata atttttgcag gtactcctcc
    56641 aacaatagaa tacggtggaa cgtcattagt aactactgct cttgttccaa taattgcacc
    56701 atcaccaata tttacacctg acataattat agaatcataa cctatccaca catcatttcc
    56761 aattataatg ttacccttat tgtcccaagc gtccgttata tggttgatat cgagtttcca
    56821 ttcttcataa aagatgggaa aagtatatgt ggattttgat ttcattgagt gatttccact
    56881 agtcattaga aattttgcat tacatgctat tgagcaaaac ttaccaatta ttaatttatc
    56941 attgtttata gggtaatgat acaatacatt gtttttctca aaatctcttg ggtcattata
    57001 aaagtcatta tatattgtgt aatctccaac ttctatattt tcccttgtta ttacattttt
    57061 aagatataca gtttgataat cattacttct tggatatacc ttatttgaac ttggaatagt
    57121 catatttaaa tctctccttt aatatatatt atgtttttga ctattccact actacaatac
    57181 atctcttcac agaatcactc cttgttaaga atcttcataa gataatggcg tcctttttta
    57241 gtgttaagtc ggatattctt tcttagtcca ttctttttag cgtataactg acaaactgtc
    57301 attttcttac caatagtgtc aatgctatca tcaaggtcat tttgtattgc tttttcctta
    57361 tcccttaatg atatatcatc acgttttccc tttgggggtt tatcagtagg tacaagtttc
    57421 caagagtaaa caaattgtgg tttaccaaat gaatatacat acttatatgc gtatcttcca
    57481 tcttttctct ggctctctcc agttcttaaa attctatctt tattatctcg tcttttttca
    57541 gttgacatga taagaagctc ctctcaataa ccgaattgag cttgatacgt catatgaata
    57601 ttataacata taaggctcaa tttcattaga taacgtcaag tgtatcaacg attttctcaa
    57661 attgttttct ctttatttga atgcgattgc tattcataat gacccagcca gaatcaaggt
    57721 tttcatcagc acgtttacgt aattttttct ctccaatacg aaagtatttt gacgcttctt
    57781 caatcgtcaa ggtatatttt tcccaaatag gtacatcagt attgttcata taatgtatca
    57841 ctcctttcta tgttcgtagt tcagaagtag atagatggct ttgataagct ccattggtat
    57901 ttcaaccaat cccattctta tggacagaac cgtgtcatac aggtgtatca ttatactgtg
    57961 gtacaggtta cggcaaaaca accgttccaa aggttattca caaatcacta tatagtagct
    58021 ctcttgatta aggtcatggc gtatagtatt tgttggctat ctgtatcaca aacgtatcta
    58081 tctactttat tcagttgtca aagaacagtc ggcattgatt tgcctataaa aaatcacaat
    58141 agcttgtggg cttttataga caaataatta gtgattctcc atgtaccaaa tagcttgata
    58201 catggagaga gggcgagatt aagacaaatt aaatctcaaa atagcagtga ttagttttgt
    58261 tcctagcatt cgctttgttt cttcttctac atgaatatag ggatttccgt attcatcaaa
    58321 taaagttttc tgtgaaagac gaatgatata gtgttcaaaa tgtttaagta ttacgtttat
    58381 tgcatttaca tcgccatgta cagcaagtaa aataattgta aaaggtaata cttctttagt
    58441 aggtttcatt tcaatgttcc tgcatgagtt ctttcaactc ttttagtgca tttgttttgt
    58501 gataatgtat ggtattttct gctaaatcca tcaatgttgc tatgtcagca tttgtcatgt
    58561 tgaaaaagaa tgaaagtaga attatatctt gttttctttt tgtaagtttt ccgattgctt
    58621 gcgccattaa tacatcttca attcgtatgt tgtagtcgta agaaaccata cagatgtagt
    58681 tagaatcata atcatctaaa atactcaatt tacttaattc tgcaagtgac aaagattcga
    58741 gagataccaa ataatcattt ctgcgtttat tttcgtcata aatatctcta gcatagttac
    58801 gcaaaactgt tttacagaaa ctgtcgaatt gatgttcaat tgtcttttca tcaaccataa
    58861 gatttcaccc tctttccatc gcaaggagtt aaataacctt gcttactcct atcacggtgg
    58921 gagggcgtta aatcttcgat aaatttcaaa aaaaagagaa aaaaatacac actctgccta
    58981 tagggcaaaa atgtgtattc tttaaaacgt atttaattta tattggttgt aagccaccac
    59041 catattgatg tatggaaata tgcattggct agcttttcat aaaaatacaa agatgcataa
    59101 gaaattaata gaggggaaaa acttattctg ttattaaaaa gtaggttaat tctaataaat
    59161 gctattgcgg tcgaattaaa ctatatacat ggcaatcaat catgtttcta ttctttatta
    59221 tgaattgtga cagtattctt caatcttaaa gccacatttt tccaatactt tacttgactc
    59281 tctattgtag gaatatacat tagcatgaat tttgttaagg ttgtattttt caaaggcaat
    59341 tttgcatatt tcttttactg catttgttgc tatccctttg cctcaatagt tcctagcaag
    59401 ccagtaacct aattcagcat ttttattaat agaggtatct tcttcaaatg ttaggctgat
    59461 acttccaata gccctttctt gataaaaaat agcatagcta agttgtttaa catctgaagt
    59521 tgccaaacaa aaactaacaa aatctctagc gttttgctcc ctataagggt gggggaagtt
    59581 gtcacgaaga ttctttgcaa tttctttatc attcgcaaac tcaactaaat cggtaatata
    59641 agcataattc cactctataa gttccatttt tcttctcctt ttatgaaaca gctacaagaa
    59701 atctttctaa gccaatacca cttatcaaac agcgttctct tttatttcca agcatttgat
    59761 aagtccagtc aacaaatcca ccgtcaacta tttcaacggt ttcatttcct tgtttgaccg
    59821 ataatttgaa attgatacct ttataataat tattatcaac atcatcatta tgaattgata
    59881 actctatatt aggaaaaata agtttgatag tttcaaccat tctgtcgaaa aatccgtcat
    59941 tatctttgta tccgtttctt ttgcgtagaa taatagagaa acgaacattt tctatttcac
    60001 ttaatatatc tttataatag tttaagtgct tttctaacaa cattttttca caagtgtaag
    60061 accctgtatc tataccagat gaaaccatac aatataagcc aaaatgtgaa tataaacctt
    60121 tacctacaaa attttgtgct cttattaccc tagcagtagt agccatgtgg ataggtatgg
    60181 tattattttc ttcttttctt tttaatttat cagcaataat tattgccaac atatttgagg
    60241 ggtctgcaag tgtttctgtc cctcgtagag cacttactac gttatattga tctacggagc
    60301 caaaaacgct acagctacct aatggggcag agggagaaag cataatcgtc ttgatatcca
    60361 tattgaatgc ttttctcaat aattttgatt ccaaagcatg aatttcttct ggatctatac
    60421 cgctagggat agtaaatcta tttagttggt atgactttag aatatcagtt gcagttaaag
    60481 tatttgcttg tctatcaaac acttctaata gaagtgagtt caaatctgat tttgatagag
    60541 ctgataactt atcaactata ttcttatccc caattttatt tgtaattcta cttaaaatat
    60601 cactcatagt tatcctccat actgttactt tcaaaataat tatagaattg ttacaacaac
    60661 taatctaggt catttgacca aaaatgaaaa aacactgaat atttactatt caatattttt
    60721 ttactttggg tttatttgat taaatcttga aaatactgta atgcaaccct ttcagcttca
    60781 acctttcgga caataggact ttgtgataat tcctctctta actcaagata caggttgata
    60841 gtagcctgca atgcattaac acagctttta tattcatggt tagcaaccgt cttttctaat
    60901 gcttcaatat attggggtgc gtccaattca atttttctaa ctccacgagg taatttacct
    60961 aagagaagct gtattaatgg ggcaagtact gattgtctta aaaaagataa aaaatcaatt
    61021 gtttcaaata gttctctacg tccaatctta gtgcaagcgt aatgaaccca aatccaaaat
    61081 ctatcttcaa tccactgtaa gtctggagtt gggaagtatg cttctttttt agaataaatt
    61141 tctgttatgc agttgttttc ttcatagaga atagctgaat cttcaaccct atctagtaaa
    61201 ccatctaagg ttgtaaactt aaaatcaaca tgaagaacag gggaatcata gagggaaatt
    61261 atcaatcgag gttctccaac gtgttcgcca gtaaaagcag aaactaatgt tccaaactgt
    61321 tccacaataa gtaatctctc ttcgataact tcttcatagg atttatcatc tgctacaatc
    61381 agaaaatcca aatcagaata ttcatctaac gattttgtga tataagaact gctaattgca
    61441 agtcctatta tcctactatc tctttttgaa aattctaata cgttttgtat cattttctgt
    61501 tgtgttttag tcataatata acacctctca ctgtctttta ttagctatca atccaacata
    61561 attatgcata ggagtattat ataatgaaga aataaaaaaa aataggtcac ttgacccgaa
    61621 ataaaaaagc attgaataat tattattcaa tacttttttg aaattatact tatgttgtag
    61681 gaagattctt taatacctct cgctgattaa ttacactaaa tcttttgttt tcataagcaa
    61741 ttagatgttc ttgtacacat tcatttatag cacgattaat gcttctaatt ggagcgttta
    61801 cttcgctagc aagctgtttt ttggtaagca gatttaattc acttctataa tagtgtaagg
    61861 atatacacct cagaagtcgt tctttaacac ttaaagatga taattcttca attaattcag
    61921 catttacaac taatttacta gatatttctc gaatcagaaa ttttgtagct tcaaaatctc
    61981 cccttaacca gtttaaaaaa tcatctctat gaagtttata tacattacaa tctgtgaaag
    62041 cgacaatttc aacgggtttt ttcccatcat taaattgttc catttctcca aaaaaactac
    62101 cacttctata aagatgaatc gttgagatgt ttcctttcac atttaagatg aatgcttctg
    62161 caataccgtc aatcataaga attacatatt cattttcttg ctcagcaaaa agaatagtct
    62221 ctttcttttt atacgttttt ttaacaagct tctttttaat atcttcattc ataaaatcaa
    62281 ttaaatgcat attcatccct ccttaccaaa tctttgatta aattatatca tctttcaatt
    62341 agttaggtaa gatagtaaaa atatatttac atagaaacta ttccattatt attttccagt
    62401 tgtcattttt ctgcaaaaac ttatcactgt cacgactgga gataccagta aggaatgtta
    62461 ggatatcaat cgctaaactt tcagaatcct ttttacggct caaaatgacg taagggtcaa
    62521 gcaatccttt gttttcatca ttactggtta aattgacaat gtttatctca tgggctattt
    62581 ctggtagcgt ttctttccat ttgccgcgtt ctgctttagg gtcaactatg accgcctgtc
    62641 cgccgaatag taccgcatag taaacaagca tattgttact gaataattta ccaccaccca
    62701 atgaaccgat aaacgcagac gctaacgcat tggtaataga accctttacc ccttgactag
    62761 caagggcagg ttttagatag acattctttc cagtgtccag attgtagcca agatagatat
    62821 cctcatgttc gccaagggtt tgtgtcgctc caaaaccaag tccagccaaa aaatccgaag
    62881 tgacatattg aatataatca ttgatgtaac gtttgctgac aggaataaat tcgccatgca
    62941 atcccaacat atccccaaag ggacgcacga gcttgattga taagtcgtcg taaaagtctt
    63001 tgacttcatc acaacgcctt tttagctcgt caagattctt tgtagataca cggacaacat
    63061 agctaagttt atacatagat tctttacagt taaaagtctg tttttaaaaa aatgtataaa
    63121 ttataaatca aaatatagat actatcaatg acccactagg tgcaaaaagc attgatatgg
    63181 ttaaattatc agacgctaaa agctgggcta tccgaatgag tgaagatggg tgtgcttata
    63241 aatccattga caattataag cgctcactga aagcgtcgtt tttcatggca attcaagacg
    63301 actgtattag aaagaatcca tttaattttt agttaagtga tgttttggaa gatacaacag
    63361 aaccaaaaat cgctctaaca ccagaacagg aaatgggctt attatccttt atggggagcg
    63421 ataagactta ttgtaaatat tatgatgatg ttgttatcct cttagaaaca ggactacgca
    63481 tttctgaatt atgcggtttg actttagaat tggatatgaa aaataaagcc attatggtag
    63541 accatcaatt gttgagtgat actaagattg gctattatgt agaagttcca aagaccacac
    63601 agggtaagcg agaaattcca atgactgaaa gagcttatca atcatttgaa cgtatcgtgg
    63661 aacggcgtaa gaacgctaaa gcagaaccaa tcattgttga tggttaccag aacttcctat
    63721 ttcttaaaca agatggatta ccaaaacaag caactcatta tcaaagcatg ttaagagcgt
    63781 tagtcaagaa gtataataag acccatgagg acaagctacc aaagattacg ccacatacct
    63841 ttaggcatac actctgtaca aatatggcta acaaaggaat gagtcctaat atattgcaat
    63901 atattatggg gcataaaaac attactatga cgcttggcta ttatgcacat ggttcattta
    63961 gttcttcgag agctgaaatg gaacggttat aatcctagta gtatgactag agtttactac
    64021 ttatttacta cttttgatgg cattcttata cggttaaatg ccaacttatg caaagtatct
    64081 tccaaaaaga aaatgccgat actccttgta gatacaggat atatcgacat ttaccaactt
    64141 atgaaaagat aatcaaattt aatataagtt tttcaaataa aaagatacca aattcttttt
    64201 cgagaatcta tataacatta cttaagcttg gttggggtat aaacaattga gtagctactt
    64261 ttgtatggtg ttcaacttta gtcaaaactc ttaagtaatg caaatgattt agattcatta
    64321 atattcaatc tcttcataag tagtgaaatt cgagttattt ctgcataatt atactatgat
    64381 ttatagatta attctattag catccagaat aatattgttt atatgagtaa aatttaaaga
    64441 atattgtgaa aattatagga tgttaaaata aatttaggta aaaaagaagt gtttgtatat
    64501 tatagagtac cttttctaaa atatgtggga ttgttttaag aattagaata aaaattattt
    64561 ttaaattagt atttttataa tgtatagtat ttttaatgta taattaaatt gtgcagaaaa
    64621 tagaatttaa agtcctatag aatttctgat tatggaggag aatatgaaaa gaaaagttca
    64681 agtaaaaaat attactattg gagaaggtag acctaaaatt tgtgtaccaa ttattgggaa
    64741 aaataaaaaa gatattataa aagaggctaa agagttaaaa gatgcatgtt tggatattat
    64801 agagtggcga gttgattttt ttgagaatgt agaaaatatt aaagaagtta aggaagttct
    64861 ctatgaatta agaagttata tacatgatat ccctttatta ttcacattta gaagtgtagt
    64921 agaaggggga gaaaaattaa tatcaagaga ttattatact actttgaata aagaaatttc
    64981 taatacaggt ttagtagatt taatagatgt agagttattt atgggagatg aggtcataga
    65041 tgaagtagtt aattttgctc ataaaaaaga agtgaaagta attatatcta atcatgattt
    65101 taataaaact ccaaaaaaag aagagattgt atctcgttta tgtagaatgc aggaattggg
    65161 cgcagattta cccaaaatag ctgttatgcc gcaaaatgaa aaagatgtgt tagtgctact
    65221 tgaagctaca aatgaaatgt ttaaaattta tgcagataga ccaataataa caatgtcaat
    65281 gtcaggaatg ggtgttataa gtagattgtg tggtgaaata tttggttctg cattgacttt
    65341 tggagctgca aaaagtgttt cagcaccagg gcaaatatca tttaaagagt taaattcagt
    65401 acttaatcta ttacataaga gtattaatta aattaattat atagaaatat tagacggtat
    65461 ttttgaagat ataaattaaa tataaaaaac ttttcagata gtaaaattta aattgggcaa
    65521 ttatatctga aaagcaacta tttagtgtgt attttgaaag tgatatagaa aatcttataa
    65581 atcaactatg gcatatttaa aatatgccat taaaacctac tagacattag attatagatg
    65641 gtatactagc atttctatta tttatagata gtaagttttc ataataactg ttttatctaa
    65701 agtagaagat atatttgtat tatgtatatt tgtcattatt tttttgtaat tatgtatatt
    65761 aatggttata tatgtaatat aatattatca ctctattttt tgtatattgt acattacaac
    65821 atttatatct atcatcatca attacagtag aatgtatggg atacttattt tcacttaacc
    65881 aatatttttg catattcttt gtccaagact ttggaaactt caatactttc ttgtttatta
    65941 taacatcctc atcttcaaaa atattaactt ctctttctat ttttattttt ctgttgtata
    66001 tcttattgat agattctttg tcgagtttta tgtctctata catatcaggg caatagcaac
    66061 aaacataatt tctttttttt cgacgtttaa atttcacaac tttctctatg ctaatttcta
    66121 atttttttgt accatctttt ataaatttaa tatcttctat gttctcgctt gaaaaaattt
    66181 ctgtcaatct taaagtatct acagtttctc taattatttg ctttttataa gaagagaatc
    66241 catatccaaa agaaaggttt aatttattag ggatgtagcc atttttatat ttaaacatct
    66301 taattttttc caattcagca ttatctttaa atttcaactt ttcataccta aaagttactt
    66361 tgctaaaaag agtatattct acatcaatat attcttttgc aatcttaaat ttatcgctac
    66421 cttcaatcac aatcatagcc tatctccaat cgttttatat taaaataagg ccatagaaca
    66481 tggtctaata gtactcatta gcactataag acaatgttaa cacaaaaaga caaaaaaagg
    66541 ttatttattt caaataacct ttttttttat ataaaatata aagaattata ttttattctt
    66601 ttttatgatg tctataatct gtgatatcag atttagttct cttgaattta agtcttttaa
    66661 ctcttcattt atatcatttt ctaaatatgt ttttccagtg gaagtaatat cttttataag
    66721 aacatctgca gaaatattta atatatttac aaattttatg aatgttttaa gacttggatt
    66781 ctttttacca ctttcgattt gagttatata ccaaggcgat actccaacca tatttgcaaa
    66841 ttcttttgaa gttaaatttg cttttttccg ttcttcttta agtcttttac ctatataatt
    66901 cattattgtt actatttccc tcacttatat ttctttgtat ttaatgatgc actttattaa
    66961 ctctagcatt gcaatttgtt ctttttcagt taatttatta atcatttcat aacattctaa
    67021 aggtacagag ttatcaacgc cttctgttgt aataatattt gcaaataaca attcaagtgg
    67081 tatgtctaaa gcagtagcaa ttttcattat aatattgata gatgtatttg tctcagctct
    67141 ttcaatctga ccaatatatg ttggatgtaa acctgccttt tctgctagaa actcttgact
    67201 atatcccaat tttgttctat agacttttat tctatctcct attatttttc ctatatttgc
    67261 caattattat ccctccactt tagattatat tcatagttta agttgtttta tatagactat
    67321 ttatactttt ttagtctaaa tatagactat atatgttttt atactgaaat aagtgctatt
    67381 tatttttgta tagtctgtat ctacaataaa caaatatgga taaatcatat ttttaattag
    67441 agaaatattt tcataatttc atagccatac tacaataata aaacgaatta ataatatgtt
    67501 aattatagca ttttttattg taattacata ttagatatgt agaatatatt ttgaaaatta
    67561 aaaaaatttt ctattttata tattgaacaa tttatgtgaa tagaaaattt ttcaataaga
    67621 cttttgagtt taatcattat attggtaagg taaacatttt taaatctaat tatatatagg
    67681 tgaaataa
//
LOCUS       DAFAZV010000021        65036 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFAZV010000021 DAFAZV010000000
VERSION     DAFAZV010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 65036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65036
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.021"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..3787)
                     /locus_tag="KOU88_001939"
     CDS             complement(<1..3787)
                     /locus_tag="KOU88_001939"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012632.1,HMM:NF024930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211829.1"
                     /translation="MKRTKLLQRGNFFGDKNMVVDEFDEGYDNYDFINFFTGCCNYTF
                     GLKNNNILYGCGDNSNFQLGLGEDNTTRKLFTKIPNISTNIKKVACGESHAVILTSDG
                     ELLVAGINTDGQMGLGLEKVGKTVSTFEKVPEIKGVKDIACGLQSTYLLYNDGTLYVA
                     GNNLYGQLGLGTNGASANVNTFTKVDVDNVKAVFSYNKSAFIIKNDNKCYSTGFNNQG
                     QLGLGDKNNRDLFSLVSINDVKTIACGSEHTVLMTYNNDIYGCGKEKCFGNALQSSLF
                     TKIEEVNIKTIACGHGNTMLIDNKGTLKVAGNNDIYQLGIANYSENIDNSFIDSKNIV
                     AKNIFIGLSHSILIDSNNDSYCTGDNTYGQLGSFFDDMHIVEFKKMDSEKYSYSNYIN
                     LIKSEDKLTLLKEEMEIKDIELPLDIHSVRDVVFSPYCTLVILGNGDVYGLGNNRYKG
                     MGSDLPSQLNELTKLSISNVKSIVASKNISGGIFYIKNDDTCYYSGPNSNSIAGVLPS
                     NSDVFKKISIDNVKKVVINTDLSNWFSLIVTNNKQIYTSGKSSSYVNGLSNALISQYT
                     EISLSNVTDAYSSYNATFIVVDEKKVYATGINTNYLLGFSTSDGSNVNLGLLSDWYYI
                     NISGSSYSRVSCTNNITKINNIIIYEYVTVFCTNIGSFLTGYHGTSWTKPTDSSYRVQ
                     YQGISYAGYLDSYIYNYYPTRCTQSSSSTTFAYLYNGESSSNLKNVNPDNLLISGGSS
                     YIHQYGRNYLNNQSSNNIAASNINSGPITSDKAIFLYKALLYLSSNTLYGFGNISESA
                     KELDVSDTQDGYNATNYKKVMKNIKNIFIPPYDLSRDKTRFAILTDKSLFICGYNSKG
                     THGISVNSSLNLNNKINYNKKNSSSEISSNIQEIYSHSKSTYLLTNNNMLYSVGLNDV
                     GQLGVGDEINRKVFTKINIDNIKSINVNRFTDNSKHAFAIKNDNTCYAVGLNNSGQLG
                     IGDNVNRNIFTKINVENVKYVAVYGNTSLLLTNDGLLYGAGNNGKGQLGLGDTTSRNI
                     FTRIPINGVRDVYLCNDVSIIVKNDNTCYVCGLVNGYFGFTEGSISTFTKINIENVKS
                     VVTAGSEATFFITNDNMIYTTGKKERVFFSTETNDIKGIRVINNIINAKKIVVNGYTS
                     AILTNDNKLFVGGLSGYGSIANNNNTNSVEDVKDVFVTANNTLYIDNNNNLISSGRDT
                     YGISDESYRDMSVPYYKVSIKKDVDTVFSSYNTIFIKDIYGKFYSSTGDNRYNHLGIH
                     "
     gene            complement(3804..4787)
                     /locus_tag="KOU88_001940"
     CDS             complement(3804..4787)
                     /locus_tag="KOU88_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3211830.1"
                     /translation="MEEKFYIILTKIGREKIANATALGELVGLTKFQVGDSNGEYYEP
                     TEEQTALKNVVWEGNINSLRIDEKNPNWIVIETILPGTVGGFMIREAAVLDNENNIIA
                     IGKYPETYKPRAEDGSIKDLVVKMILQLSNTSNVTLEVDPTLVFVTQKDIQDLDDKFD
                     KNIKEIKVKIGEELLSTEAKNLSGAINEVVEKIKNISIDDVIGGQIQTELSVLKNSYN
                     KLSEKVLDILIYLELESEIDVDEAGYWYDTLTNAKNIIAIEGLKLDLNRKCITGELGS
                     VTFKNVVLPFNANRVRYIHEMDNNFVETKSNRAYSIGQTDITLNKYSYEIR"
     gene            complement(4788..5486)
                     /locus_tag="KOU88_001941"
     CDS             complement(4788..5486)
                     /locus_tag="KOU88_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBK3211831.1"
                     /translation="MKLIDKLPSFDRNYIVEEIQGAYDTELNILKEDIDDTFNQLFVD
                     TATWGLDMWEDILCIEKKELDFDTRRSNIKAKMRSRGTSTIEVIKSICEAYTKSETDI
                     KVYSDEFTFVLSFIANNCDYKTLLDCSDMIERVKPAHLLHYLEPIILDKSMVYCGGGM
                     VCSEEVKVHPYFEPIIKCSAVVNCGAGMLSREEIKVYPLSIKCIENNCKINIAIANDT
                     GVENVVVYPKSEVV"
     gene            complement(5483..6535)
                     /locus_tag="KOU88_001942"
     CDS             complement(5483..6535)
                     /locus_tag="KOU88_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBK3211832.1"
                     /translation="MYSDQTYEVIKNRTLENINLDIYKGEGSFLNNMVSGNNLELSKI
                     YLELSKIHKMAFIQDTYNQFLDKRVNEFGVYRKLGTESNGEVEFIGEKGTVINNGTVI
                     SYRDLLFVVIKDVTIGSEEGDNSPVQALEVGKKYNLPTNCEFKLVDNISGVTKITNTR
                     SFEGGTDIETDEELKERFYKIQRNQATSGNKAHYEEWALEVDGVYNVKVYPRWDGPGT
                     VKVLIFGKNNQAVDTETIERCQQHIDEEKPIGPTITVVTPLPIEISISAVMKLEDGYT
                     LDNVKESFLESINTYLRDIRGEIIYTKVMGILINTTGVHDLSKLLINGSTDNITINED
                     KIPSVTTVNFSEVENQ"
     gene            complement(6528..6956)
                     /locus_tag="KOU88_001943"
     CDS             complement(6528..6956)
                     /locus_tag="KOU88_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBK3211833.1"
                     /translation="MSTIFPFIGVPEDYILPKTEELPIFREVAWDFEKDEPILEKGDF
                     KIIEKKEALKVWIYKCIKTNRYEHEIYSLEYGTELSELIGQKYTKGLTESEASRFIKE
                     ALLINPYILEVNVKSANFNRDVLSANVKVSTIYGEVEINV"
     gene            complement(6956..7282)
                     /locus_tag="KOU88_001944"
     CDS             complement(6956..7282)
                     /locus_tag="KOU88_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBK3211834.1"
                     /translation="MANPINEFIGIIREEGKYHNQPSFFIGKIKSKLPDLKIETNNII
                     LEKEDILIDSWMIDRQLETFDTETNQEHQHEVKNPFIDNFESGDMVIMFRIGEKFAVV
                     SKLVSL"
     gene            complement(7298..8827)
                     /locus_tag="KOU88_001945"
     CDS             complement(7298..8827)
                     /locus_tag="KOU88_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK3211835.1"
                     /translation="MIINRSKDSSSNEISFVSKDMGFLLTQSEVSYNFKDKLVEDIAK
                     QVFAENRLSVGTIAKTNVKYTKMFIGVNGYDTIMSAYTEASKKTKKKYMIEANLDKFN
                     VIEKGIVTLNVMFEEGFNIINTTFSESMENVKNKVIVVDQYGSKISEKIDNEIFKEVN
                     VIMQKVIQQQENQDVDIDSEFNGIEKSCSLKGYGDVSCITGRGVKVKDSYTKLVGLFY
                     IDTDKHTWQNGEYQIELELNFQNLMDEKSAGQDEPKEESNLGGEDYAGGKEFTAEFTA
                     YCPRKEEGGDTDCRKKKLDPSKKTCAAPMVGKYEQTYYTKEFLNKHPLLNYGDEIQVI
                     TGVSGRDGVYKVNDVGPAITIEKNGTYHIDILFGNVEEASKFGRRKGKIIIGGYSGNV
                     SDKAKIVISEAKKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVSLPRTSNQQSKKGK
                     KVEQKNLQAGDLVFFHNPVSHVGLYIGNGEFLHAPQKGDVVKISKLSSRRDFNTARRV
                     L"
     gene            complement(9109..9531)
                     /locus_tag="KOU88_001946"
     CDS             complement(9109..9531)
                     /locus_tag="KOU88_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211836.1"
                     /translation="MEMWLRQAEDRFRFPVFPSSFSINGKAAVNSSSILKIGEIATFG
                     GVALKSISISSFFPNKDYTFCDYTGFPSPYDCVNKIEKWMKEGFILRFTITETNINME
                     VIIEGFSYEERDGTRDVYFTLDLKEYKRIKIPKVTPKQ"
     gene            complement(9531..11984)
                     /locus_tag="KOU88_001947"
     CDS             complement(9531..11984)
                     /locus_tag="KOU88_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211837.1"
                     /translation="MGNVREEGINMYLTDNYTPKMNQIISVTDNFRRATVAVSLSTNV
                     MASSIKNSIGSASNRVNSLNSSLRKVQTTASSVSSTMTKLSSSINAVSGVIGSLNGSI
                     MRLAITIAMIIDYFNKLIQKKNEFNSNIMIILIFKAKSDEVEKTKNKLLGNLKKIGGK
                     IWNIVIKAKDMTKRVISSILGKLKQVEKRPYQGSINLKDMVSSAMGRILPKLMLFKNT
                     FWSGVIAIKDMASGIISKVFPKLRLFAGKVWSGAIAVKDMASGILGSIKGKISDLTNG
                     ATIGVAVKKGVDLLGQEQNQKVVLESVMKRNTGKVNQIDVDDYYGSLVRMANDTPFDP
                     EDVVAMGTKAKMISNITGGKKEKDITQAMVDVRALNMNTSSEQDVSAAFLSAAKGNME
                     SLNTLVGENYKTFDEALEGISVKQMGLAKEMSNTIPGIISGAQTSINNGLKSIVKPFD
                     DILGQGLKKIKTFIESGLGNLAGLSEKMAGKIGNVMNGKIIIGNKYDQMQSRSVKNGK
                     EFSDSTQYRISNEAEKRKMMVENKQERFENHAATMIGNAPKAIVNAGSTLLQNIDFTA
                     LIDSLLPVVNLVNNLLDSINNKSPIAQGLISIFGTIVTTAFQLIGPVVEAVSPIITRI
                     FTFLGEYAPQINNFIETLGVIWKTVWETLGPLLETGWKIIEPILGAFFNILDKVCKIV
                     KDICKWWQTMINKIKNGSITGTVLNLVEKSKKNYKDNPYAGTKAGDSGKAYSGKKGNN
                     AFGLNYVPYNDYQTRLHEGEMVLTKQEANQYRSRKNGGNINIAKLADTIVIREEADIE
                     KITSKLVASIQLAQLGGVL"
     gene            complement(11984..12151)
                     /locus_tag="KOU88_001948"
     CDS             complement(11984..12151)
                     /locus_tag="KOU88_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211838.1"
                     /translation="MYYYWKKKGIRPSLFYAMDKGELKLIEAFFALEIEEEVEKMKHG
                     YGVCPLTGGGM"
     gene            complement(12178..12624)
                     /locus_tag="KOU88_001949"
     CDS             complement(12178..12624)
                     /locus_tag="KOU88_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3211839.1"
                     /translation="MSENGLLKNINIVDLLLNADTENLERPSTIVELKRLSTIFGQEF
                     KVMCRALTISKDEEIQNTCLKIDENMKTDIDLPEMQMLTIIEGVCDLDGKLLFKNKEL
                     MDKFKAPTPKELARKLLLPGEITNLYRILQDVMGYGKNAVIEEVKN"
     gene            complement(12750..13178)
                     /locus_tag="KOU88_001950"
     CDS             complement(12750..13178)
                     /locus_tag="KOU88_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBK3211840.1"
                     /translation="MANMEARNVMSGTWGELWLDGNKVAEVKKFQAKMEFTKEDIIIA
                     GQMGTDTKYMGYKGKGSITLYHVSSRMHKLIGEKIKRGSEPRFVAISKLNDPDSYGAE
                     RIAVKNIAFDDLTLADWEVGVKGEIEAPFTFTEYDFLDII"
     gene            complement(13192..14256)
                     /locus_tag="KOU88_001951"
     CDS             complement(13192..14256)
                     /locus_tag="KOU88_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBK3211841.1"
                     /translation="MAIGLPSINISFKELATTVKERSARGIIAMVLKDAKALGLNEIH
                     EKEDIPVDLSAENKEYINLALMGNVNTPNKLLVYVIEGEADIQTALDFLETKEFNYLC
                     MPKAVEADKTAIKNWIIKLRDIDKVKVKAVLGKVVGNHEGIINFTTEDVLVGEKKYSV
                     DEFTSRVAGLIAGTPLSQSVTYTKLSDVVDIPKMTKVDAESRVNKGELILIKEAGAIR
                     IARGVNSLTELTAEKGEMFQKIKIVDTLDIIHSDIRKVIIDDYIGKVTNSYDNKCLLI
                     VAIKSYLEELEKSALIESDSTVEIDFEAQKSYLKSKGVDLSYMTLQEIKEANTGSKVF
                     LKAKIKVLDAMEDIDLSIEI"
     gene            complement(14261..14704)
                     /locus_tag="KOU88_001952"
     CDS             complement(14261..14704)
                     /locus_tag="KOU88_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211842.1"
                     /translation="MLKYKEILETIIEILKKNFTESIFIDDESVQGSEGSCFFVSILS
                     VICTPIMLNTNNKDIVISIKYLPKPQSKSIRMYEISDELNKLFNRNIKVTDRKLNITK
                     LEQSIKKEESIYVLNFTFTLNYLDSVYEEDVVYENMEEINLNLGE"
     gene            complement(14953..15393)
                     /locus_tag="KOU88_001953"
     CDS             complement(14953..15393)
                     /locus_tag="KOU88_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211843.1"
                     /translation="MENKKDILFKETDKRLHNYKYLDIKIKNINLDIKRCENEYSGCG
                     AMVYTEKTSNTYNISSSVENEVLKREERLRKLKMEKEDIEIEKEKIENALTCLNDIEM
                     EFFNLFYNSKTKNNMTYISMKLHLDRTSCYNLKKKMIFKLSEIL"
     gene            complement(15498..15695)
                     /locus_tag="KOU88_001954"
     CDS             complement(15498..15695)
                     /locus_tag="KOU88_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3211844.1"
                     /translation="MFKNNLKYYRKCKGMTQIQLARKAGITNDYISQIERGIKNPGLL
                     MAKKISSILEQNIEEVFFIQS"
     gene            15864..16184
                     /locus_tag="KOU88_001955"
     CDS             15864..16184
                     /locus_tag="KOU88_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBK3211845.1"
                     /translation="MFAKRLRELRKEFGLTQRELGEKVGVSQRVLGYYETENRFPDEH
                     ILNKLADVFNVSVDYLLGRTLVKENIDTVAAHRKNPHEELPEEAQEQLNDYIEFLLNK
                     YKKK"
     gene            16266..16772
                     /locus_tag="KOU88_001956"
     CDS             16266..16772
                     /locus_tag="KOU88_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211846.1"
                     /translation="MNNLDKLFELASQEGIIIHYTTYIAGDLEGLYINKHGIKIISLL
                     SNLKQNSKKLTSILAEELGHHFTSLGYYVSSYNDYYTKIIIDKCENKALKWACEFLIT
                     EEDIINIINSGITCVYEMADILNVDITFFQKRLEFLSLKKQSLQLGNNKYLILTNLPY
                     FYIFDPIS"
     gene            17473..18228
                     /locus_tag="KOU88_001957"
     CDS             17473..18228
                     /locus_tag="KOU88_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK3211847.1"
                     /translation="MEKKVLATVGEKEITNIDIENALKSLDPYQAMQFKTEEGKKHLL
                     NDLVNQELFFLDAKEEKLDEEEIFKLEMKKIEENVLKQFAINKVLSSVNVTEDEKVKF
                     FEANKSSFSKPESATAKHILVDSDEKAKEILAQIKSEEISFEDAALKHSSCPSKDMGG
                     DLGTFGRGQMVPEFEEAVFSMAKGEVSEPVKTQFGYHIIKLEDLQESTESTFDEVKAE
                     VEKSLLYQKQNEVYGNKINALNAKYGNLVKYND"
     gene            complement(18371..18799)
                     /locus_tag="KOU88_001958"
     CDS             complement(18371..18799)
                     /locus_tag="KOU88_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK3211848.1"
                     /translation="MNILFFLTPKSEVAYIYEDYTIRQALEKMEYHKYSAIPIISKDG
                     KYVGTITEGDFLWTLKNDLNLDLKGLEDVPVTDINRKMDNSPVSINADIEDLVIKSLN
                     QNFIPVIDDQDTFIGIIKRRDVIGYCYEIIRGYKNLANDN"
     gene            complement(19220..19420)
                     /locus_tag="KOU88_001959"
     CDS             complement(19220..19420)
                     /locus_tag="KOU88_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK3211849.1"
                     /translation="MKTGVVKWFNNEKGFGFISVEGEGDVFVHFSAITGDGYKTLEEG
                     QSVEFEVVDGAKGPQAANVVRL"
     gene            complement(19603..20772)
                     /locus_tag="KOU88_001960"
     CDS             complement(19603..20772)
                     /locus_tag="KOU88_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HBK3211850.1"
                     /translation="MGGVALKILKNKNKYIKGIMAFVFLSLATTAGVFLINDLSMKNM
                     EEKVMESANVEGDDVKDQYKLLLENLFDYRNKAILEKNENILKGLYETDKKFGLWAYE
                     NEVKKMKYLENWSSKQGVKFKDIKTRVKIKKIKEKEKDLYGIICSVSTEYKYSYENQK
                     DKENAFRIGTYHYLNVKIIDNQYVITKEWYTDPFADSLNLENIKSEDIRNYIGQQDGV
                     ELQLTDEQKKAIDYAHKYCGAAADEEHGMKFNPNYRDYNPEGGDCANFASQIMFESGR
                     FKKNSIWNYSERAGTKAWVNAQAFKNYALYSGRGSLIAKGSYEEVYKEAYNLRPGDFV
                     GYEKKGRITHVSTVTGLDSRGYPLVTCHNTDRMLVPWDLGWSDKSIRFHIIKINY"
     gene            21008..21829
                     /locus_tag="KOU88_001961"
     CDS             21008..21829
                     /locus_tag="KOU88_001961"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine kinase"
                     /protein_id="HBK3211851.1"
                     /translation="MQKKVAAINDLSGIGKCSLSVAIPILSALKVQCCPFPTAILSSQ
                     TGYPEFTFLDFTDEMVKYSNVWKNLKVNFDSIYSGFLGSKHQIEIVANFINDYPNAFI
                     VVDPVMGDNGVMYPIFTEEMRQEIKELVKHSDLTTPNLTEACFLTGNDYTKSDYNRDE
                     LIHIAKSVSDLGPSKVVITGILEDDNILNLAYDRDNDHVFFTSVKYNNCSYSGTGDIF
                     TSILCGMLVNKHDLGVAVNTATDFIYKTINYTSQFDTDRNDGVMFENFLSDLTNI"
     gene            complement(21905..23293)
                     /locus_tag="KOU88_001962"
     CDS             complement(21905..23293)
                     /locus_tag="KOU88_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase"
                     /protein_id="HBK3211852.1"
                     /translation="MLGGKKSNNKKVEKLRTIFIKYLSLFFIMTISIVLLLMLSFSVL
                     LSSGVILPANYAEKQFNKYKEQIISSEKVTEDIIPSIYEYGVYTLDGNLISGTFNKKE
                     SKEVWNLMRDIEERHAYSESYIKFFKKDEVFIIKYKIVSEYSSPILRAYLPKPETLGM
                     IIFSIIFFIEIVILSKVFGKKFNIEMELLKNTTEKIEQQDLDFVVESSKIYEINNVLF
                     SMDKMKLALKDSLEKQWMLEENRKEQISALAHDIKTPLTIIHGNTDLLIEINENPELL
                     EYMEYISKGVTQIEKYINTLIDISKTENGYILNKEAISMSEFIKDVLVQIEALASTKN
                     LDVEFYKQDNLPKNITIDRELLFRAIMNIISNAIDYSPSQSKLYISVSVRNKYLKFVV
                     TDCGSGFSKADLSKATEQFYTGDLSRNSKSHYGMGLYIVNNIVQKHNGTLCIENSVKT
                     GGAMVTIEIPIV"
     gene            complement(23428..24186)
                     /locus_tag="KOU88_001963"
     CDS             complement(23428..24186)
                     /locus_tag="KOU88_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutG family
                     permease subunit"
                     /protein_id="HBK3211853.1"
                     /translation="MRQLIRIFCSDLIKLKRNFIILMHICIALMGMGLFLWYYKVSGA
                     DNILKIVAYLQVIAIAFPLLSSVVCSMFVEQEYYAGNYKHMLTTSNPKYLTLISKYII
                     LVCLGFVATLVSVLGFKFGISKAYFTSSFYMISILILIGCNLFEYILHLFLSLRFGKG
                     TSIGVGIVEMLLSALLLTGLGSAIWQYFPCAWGVRFITIWSSFSSSKTVEYIKVESIK
                     AYQSTGLMCGFVTILAFVILCIWFSKWEGKKSEE"
     gene            complement(24188..24904)
                     /locus_tag="KOU88_001964"
     CDS             complement(24188..24904)
                     /locus_tag="KOU88_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic immunity ABC transporter MutE/EpiE
                     family permease subunit"
                     /protein_id="HBK3211854.1"
                     /translation="MERFIRVEFQKMKGTFGMKLIWIVPVFCILLCGLGGGQNAAFNW
                     WYTTFLPGALTLICSLIVLKDEKSKYRGILPLPIEMKDVWTGKMIYCIICCFIASIIS
                     AIGVVFVGIIYKETISIGQNIIATILIILLFMWQIPLCMFLASKFGIFVTVLINMFFT
                     IVGVAVFSTTEMWYIFPYSIPSRLMAVVLHILPNGLPVPEGSEFLNNAVILPGVLISI
                     VLFVLFALATRVWFNNREVK"
     gene            complement(24906..25613)
                     /locus_tag="KOU88_001965"
     CDS             complement(24906..25613)
                     /locus_tag="KOU88_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic protection ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK3211855.1"
                     /translation="MSNYILQVKGVSKKFKEQMAVDNISLAIKSNSIYGLLGPNGAGK
                     STLLKMITGILNPTSGKIMFEGHRWTRKDLSNIGSLIESPAIYENLTARENLKVHTTL
                     LGLPDSRIEEVLETVDLRDTFKKRSGQFSLGMKQRLGIAIALLNHPKLLILDEPTNGL
                     DPIGIEELRELIRSFPKQGITVILSSHILSEVEQVVDEIGIISNGVMGYQGEVSKEQN
                     LEELFMKVVAENRKRGQ"
     gene            complement(25729..26265)
                     /locus_tag="KOU88_001966"
     CDS             complement(25729..26265)
                     /locus_tag="KOU88_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK3211856.1"
                     /translation="MNKIAVSFLIIATTLLSTACMDYSISAVELVDSKESAVVKKDED
                     AKEETTSKMINSKKTTKIPIEIISKDEKIVKYLQIDEESSLKDKLRLILDTLSNEYFN
                     GLDMEVEVKEKDNLVKINLIEPDKKSRVSWKDDYLNEQNIIYTINNIIKNVIQEEDNS
                     IWIEEVEIYYNGKLIELR"
     gene            complement(26367..27437)
                     /locus_tag="KOU88_001967"
     CDS             complement(26367..27437)
                     /locus_tag="KOU88_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBK3211857.1"
                     /translation="MNKKLAIFAAVLLVIGIIGTTWSGILVMPSLINFGLEKEAELNK
                     ENKLYQEKVNIDKLDIAVDNINVMIRKSSNEDVRVTTRGNNEFYKYSVTLQDKTLVVK
                     GERKSENKIKKIRSFDHLLNTSINSMFSRDYREIRIYVPNNVDINASSISSYLFISDD
                     VDSNNITYKTSSGGFSRAITENKVNRLENLNLISNSNLHLSTKSILGVKNVNIESESL
                     DISSENGDVFINNIEEYIPENVNIKEKIGRNSNYESEFYLYSDMPIAKFLDIEVPNSK
                     VRLDIPVNKYKFNCDIKSKEAIEEFNNDEEYDNDSYDYEHNEEHSNKYRNTREIKGLL
                     NKNLSNLEKEYTIKINSNSLEL"
     gene            complement(27430..28488)
                     /locus_tag="KOU88_001968"
     CDS             complement(27430..28488)
                     /locus_tag="KOU88_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBK3211858.1"
                     /translation="MNLNKTEFLEILKDYLKKDFSESEVNDILRDYEEYFVDGLIEGK
                     SDMEIIASLGSPKSIAKELILQTKEKNIEEEKIINTDVLNDKFSKFKSDMKKGYSILK
                     DEAKEKYSKSKENIDGKIMNTDILNGKFSRFKSNVKKDYSILKDEAKEKYNKSKENIN
                     DKLTPSIEEGVGGLSRQVIKGLLVVLSLFLIVPAFAFVCAIVSATIALVCSLIAFVIL
                     IPFVIKFIAMVPDVMMFCIFATIAFVGLEILAWQILLFAIKLGKQLLNNYIHWIKRKN
                     IYIKANEKMEKRKKATLNDEDLNKDINEDSYNNDYYNREEESIKETDEYNDDSINFEA
                     IYKDLEDIENKKGEDKHE"
     gene            complement(28475..28807)
                     /locus_tag="KOU88_001969"
     CDS             complement(28475..28807)
                     /locus_tag="KOU88_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK3211859.1"
                     /translation="MNTQFRKGVLEICVLALISKKDMYGYEIVHNISKVIDVNEGTIY
                     PILRRLTKDLYFETYILESNEGPARKYYRITSLGKENLSNLMEEWREFVKAVEILISE
                     DEGGNELE"
     gene            29006..30127
                     /locus_tag="KOU88_001970"
     CDS             29006..30127
                     /locus_tag="KOU88_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyldiacylglycerol synthase"
                     /protein_id="HBK3211860.1"
                     /translation="MKDDKTILILTAQFGAGHISAAKAVKECIIEKYSNYNVVIQNFI
                     NASIPMMNKPMVKLYENNTKYTPGLYNYYYYFKKSFDSRHDLSHKLYTPKLSEYIADI
                     NPDLIISTFPLAAACVNNFKIKNPDINIPTLTVITDVVDSMEWVFENTDLYFVPSPEI
                     KNRFFQKGINPDSIKVTGVPVDKRFQIESKELCCDKYRLLLLGGGRGLFDIDEDFMHW
                     IDEFIEEHSNSIEITIVTGKNKKLYDNLTHKKPLKNIKVLGFVNDMYNLIRECDLMLT
                     KPGGATIFEAIQSQTPVLVKMPKVGQEIENAKFIIDKGLGMIYSDDLDLKNIFYKLVS
                     NEFDSIINFMKKNLKEFKTVIHPEKIADYISELIDNHYS"
     gene            complement(30255..32153)
                     /locus_tag="KOU88_001971"
     CDS             complement(30255..32153)
                     /locus_tag="KOU88_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HBK3211861.1"
                     /translation="MDSLLYVIEKDKHTNEELREILKSNKNIRFVSLMGVDLGGNATD
                     EKIPVELFLEDIDKFLESAIQTDGSSVELYNIATLNNAKVDLMPDKSCHWYVDYNMEY
                     IDEEVGLPVGTLKIPAFLIHDNKKVCSRGVLQKADKYFKKSMYEIFREYPHVINNIGI
                     DSVDDIEEIMLTAATELEFWVNTPEDKADLEKLYVSQSLKEQYWKRTHGIIRTCLEKS
                     LIILQKLGVNPEMAHKEVGGIQSSISIDGRTNHAMEQLEVSWKFSTPLQAADNELLVR
                     DVIEDVFTSHGLEVTFKAKPIHGVAGSGGHTHVGVSAKLKDGSIKNLFAPKDLKEDYL
                     SELGYGALMGLLYNYEVLNPIVTASNDGFNRLVPGFEAPVCIVTSLGHSYEIPSRNRS
                     VLVGLIRDMKNPKTVRFELRSPSPLSNTYLVIAGCYQTMLDGIKAAAKSGLSTKELEK
                     ELSKNVGEESFYLEKDRAYRDENDVFEHYSLEERNARFGIPPATVYENMKNLEIYASK
                     LKSLKQGDVFTDSIIESFKIGAIDKWQKKLKTRIIEAGIQKIRSIVKIHTKENMDALD
                     EVVWNSISDLKFNIMKDTLTRESLFTRVREAIENKDYQTASDLQIELKRSMEEIQQLY
                     MQYKKNIY"
     gene            32468..33244
                     /locus_tag="KOU88_001972"
     CDS             32468..33244
                     /locus_tag="KOU88_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBK3211862.1"
                     /translation="MEYIIFDLEFNQGFDKKLNKTVSNEKCPFEIIQIGAIKLDSKFN
                     IIDTFNSYVKPTIYKDIHPFISRMTNIKNSDFNDSPTFPEVYNNFIKFISSQDPILCV
                     WGAGDLKELYRNINYHKLPSNSLPKSYINIQQHASKYFNNPAGKSIGLQNAISILELD
                     EKMSYHNALNDAYYTAKVFIKIYNPSIVPDIYLYTSIKPKTIRYSNKKRVDYDKLFDE
                     FRKILNRELTKDEKKIINLAYNMGKTNQFTLENVKQRKNK"
     gene            complement(33336..34088)
                     /gene="xth"
                     /locus_tag="KOU88_001973"
     CDS             complement(33336..34088)
                     /gene="xth"
                     /locus_tag="KOU88_001973"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBK3211863.1"
                     /translation="MKFISWNVNGIRACVGKGFLDFFKEVDADIFCLQETKLQEGQIE
                     LDLPGYFQYWNYAERKGYSGTAIFTKKEPLKVMYGINIEEHDKEGRVITLEFEDFYFV
                     TVYTPNSQSELKRLEYRTRWEDDFIDYLTKLDNHKPVIVCGDMNVAHKEIDLKNPKNN
                     MKNAGFTKEEREKFSKLLDSGFIDTYRYFNPDKEGVYSWWSYRFNARKNNAGWRIDYF
                     CASKKLEDRLVSADIHTEILGSDHCPVELEIK"
     gene            complement(34249..35199)
                     /gene="galT"
                     /locus_tag="KOU88_001974"
     CDS             complement(34249..35199)
                     /gene="galT"
                     /locus_tag="KOU88_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBK3211864.1"
                     /translation="MKELRIDPITNDVVIFATDRLKRPLDTADIPNEDEETNEYDEEC
                     PFCKGNEAHATDALFEIDSEEGWLVKSVYNKFPIIDDMARDVYGVHEVMIESDKHNRS
                     FYNMSQKEFEDVFFMYRNRFRDLSKDDKVEYVSIFKNFLRKAGASLMHPHAQILSMSF
                     IPPEITNELLVSKEYYDSNKSSLYDDLIENEISLDRRVVYNGEAFLVLIPYATKYSGE
                     VRIIFKDKIEFGELNDNNIQELSTIFEKLFKKLYNINGYMPFNLCIHTHPTKIETKSY
                     FNVHMHIIPRKYNFGGFELGTNMYVSSMSPEDLTKKLKID"
     gene            35584..36780
                     /locus_tag="KOU88_001975"
     CDS             35584..36780
                     /locus_tag="KOU88_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3211865.1"
                     /translation="MNYSNRVSAMQASPIRKLVPFAQAAKDKGIKVYHLNIGQPDIKT
                     PKGFFDAVKNFDSEVLEYATSEGIPELLEALQNYYKTYDMNFEKDELLVTNGGSEALL
                     FTMMAVCDPGDNLLVPEPFYTNYNGFGQSVNVEVNAVTTKAENGFHLPSKEEILSKVD
                     DKTKAIILSNPGNPTGAIYTKEELNILAEIAKEKDLWIIADEVYREFVYDGLEYTSCG
                     NLEGVQDRVIIIDSVSKRYSACGARIGSIACKNKGLIAQILKLCQGRLCVPTLEQIGA
                     VELYKTPVSYFKEVNEEYKKRRDVLYNELMKVEGVICKKPTGAFYIVAKLPVENAEDF
                     TIWMLKEFNKDNETVMVCPAEGFYATPGLGRDEIRLAYILNEKDLHRAATLLKEGLEQ
                     YVALQK"
     gene            complement(37115..37567)
                     /locus_tag="KOU88_001976"
     CDS             complement(37115..37567)
                     /locus_tag="KOU88_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3211866.1"
                     /translation="MNYIVKDTISFLVKTFPKIYSSLYLEDLKKFAPDYNVNKTQLRA
                     LVFIKNYGVISMTDLCSKLNIEKGSLTSMVDDLTDKKYVTRKRDLVDRRKYLIDITEE
                     GDKIATDFMDKLSDGLGEKLSKLTEEDRKKYLEAINTLQYILNKEEFR"
     gene            complement(37879..39324)
                     /locus_tag="KOU88_001977"
     CDS             complement(37879..39324)
                     /locus_tag="KOU88_001977"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBK3211867.1"
                     /translation="MIDNKYTTYSNPLTDRYCSKDMSYIFSPQFKFSTWRRLWVALAE
                     GEHELGINITEEQLDELRANIDNINFDEARKIEKEVRHDVMSHVKAYGLQCEKAKGII
                     HLGATSAYVGDNTDVIQMNEALKLLRVKLVNLINNLKEFALKYKDMPALGFTHFQAAQ
                     LTTVGKRACLWAQDLILDLEDLNYRIDNMKLRGVKGTTGTQASFLSLFEGDHEKVKEL
                     DKKICKKMGYHSSYAVSGQTYTRKLDYQVISILSGIAQSMHKMTNDIRLLQSLKELEE
                     PFEKNQIGSSAMAYKRNPMRSERIASLSKYIISESISPAMVQATQWLERTLDDSANKR
                     LAIPQAFMAADAILEIGINVTDGLVVYENMINRRVNEELPFMATETILMEAVKRGGDR
                     QELHEIIREYSMKAAYRVKHEGKDNNLIELIMNDDSFKMSKEEILSIMDPKNFIGRAP
                     EQVVEFVNEVVEPAIKDYKEDLGKVDVDLRV"
     gene            complement(39468..40376)
                     /locus_tag="KOU88_001978"
     CDS             complement(39468..40376)
                     /locus_tag="KOU88_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK3211868.1"
                     /translation="MYSTKILDDYEYETFNVFSTKLNPNTKHDYLSKVILFKEFLKGK
                     ELIYATKEDCKNFVDYIQTKYAKSTCEKIYSYLHSFYNFLKKEGYIDINPFRYVEKPT
                     VTRIKTKDDVLSIQEINKLIGILPKLNIRDRVIIVCLVTTGCLLNELVSLKWKDLMVD
                     ENDNSYVRLGKGRKERVVKLHPYFFKLLEDYRNYSGLPEVIIPSDDFIFTTQKSNSIT
                     DRNVRLIVKKALDLAGLSQYSARDFRHSFAAISLRLGADESDVKNQLGWSDKYYAIRY
                     KYVLNFVDSEIVDYLIEKDNLDINKK"
     gene            40633..41457
                     /locus_tag="KOU88_001979"
     CDS             40633..41457
                     /locus_tag="KOU88_001979"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBK3211869.1"
                     /translation="METFSLLEIFKAVILGIVQGITEWLPVSSTGHMILVDEFIKLNF
                     SNTFISTFLVVIQFGSILAVLVIFFRKLNPFDSAKNIKQKKETVRLWLKVIIAVIPSG
                     VIGILFEDDIDRLFFNSTVVAIALIVYGIIMIGLEKRNKKPKYKDFSQVTYKLALCIG
                     LFQCLALIPGTSRSGSTIIGAVLLGTSRYVAAEFSFFLAIPTMLGASALKLLKAGFGF
                     TGFEWLILGVGSVVAFVVSIVVIKFFMDYIKKHDFKVFGYYRIVLGIVVLAYFFLL"
     gene            41497..42027
                     /gene="lepB"
                     /locus_tag="KOU88_001980"
     CDS             41497..42027
                     /gene="lepB"
                     /locus_tag="KOU88_001980"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK3211870.1"
                     /translation="MSVKKEIFDWIKSIAMAIVLAFVILQFIRPSIVSGESMYPTLDD
                     KDYLILNRISYKVGKPEKGDIVVFKTNLVDGETGKKKDLIKRVIATEGDRIKISNSKV
                     YVNGKLLNEPYIHNNYTSGDIDTVVPKGKLFAMGDNRENSNDSRFPDVGMVDENEVLG
                     KVMVRLLPLDNLGKVD"
     gene            complement(42109..43890)
                     /locus_tag="KOU88_001981"
     CDS             complement(42109..43890)
                     /locus_tag="KOU88_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrD-helicase domain-containing protein"
                     /protein_id="HBK3211871.1"
                     /translation="MSQYININSQLDALKLKEFEKIFYENINEDVKVVPKVTPFKGIN
                     TDLLYVKDGRILFIKFMDTTEDIFFILEEELLEVMNEEYELLKLKMGQKNRNISYNYV
                     YIMPYVEVEETYEFEEFVNNNIIDKNKLQDIMNKGSLEEYLNDENDEINLNLFLLDIC
                     SEYYIINDKLHLNEKFKKISFYNDDYKYTATMMEDVQIKDVVSIKYGNTLIEGGSGIG
                     KTAIMLSRAIKLAKVYPHHKLVIFTHTKQLCNELRERIELLYKDNNNLEVHTFSSFIF
                     KLAKKFNLIVDYNMLKNDYEKTFNNLVKQAQNIIKNKNMFKAIFIDEAESFLEYEIDF
                     IREFLYKTKFIFNVCSCNSLNISNRLNIFKKLYNGIEFDDKIILSKNYRQAKEIVDFT
                     NKFSNNSNSYINELRPNTEFSTFFYTKALRGGNKSVDIIKVSDLDDQISSVIWEIEYL
                     ISKKGLDYSEVAIVYPYNKKKLKSGKTIYFQYMLKKALEEAKIPYICAEDNLTNISKK
                     VGTTIANIYAIKNLEYKAVIVCELEMLYNQTINDIEQDYQVNDFVGDLNKVYLAMSRA
                     TDYLSIVTTFNEEASDIIRLITESKDI"
     gene            complement(44525..46066)
                     /gene="rny"
                     /locus_tag="KOU88_001982"
     CDS             complement(44525..46066)
                     /gene="rny"
                     /locus_tag="KOU88_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBK3211872.1"
                     /translation="MDVIDSVVMIVIGAAVGIIAGYFVRKNISEAKIGQAENLAKEII
                     DKAHHDSETVQKEKLLEAKEEIHKWRTEAERENRERRTEVQKYEKRVVQKEEVLDRKL
                     QNLESKEVNLSEKLKVVEKKEEEVEVIKTQQLEKLESISGITSDKAKEIILTNAERDV
                     RREMSIMIKEIESQAKEEADKKSREIIGYAIQKCAADHVAETTVTVVSLPNDEMKGRI
                     IGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARIALEKLIADGRIHPAR
                     IEEMVEKARKEVDNIIKEYGEQAAFETSVHGIHPELIRLLGRLNYRTSYGQNVLKHSI
                     EVAHIAGIMAAEIGADIRLAKRAGLLHDIGKAVDHEMEGTHVEIGMDLLRRYKESKEV
                     IHAMSTHHGDYEPQTVEAVLVTAADAISAARPGARRETLEAYIKRLEKLEEIANSYEG
                     VEKSFAIQAGREIRIMVKPEAINDEEIHLLARDMTKKIEDELEYPGQIKVSIIRETRA
                     IEYAK"
     gene            complement(46242..47288)
                     /gene="recA"
                     /locus_tag="KOU88_001983"
     CDS             complement(46242..47288)
                     /gene="recA"
                     /locus_tag="KOU88_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBK3211873.1"
                     /translation="MSVDQEKLKALNEALGKIEKDFGKGSVMKLGEATSMSIDVISTG
                     AIGLDIAIGIGGLPRGRIVEVYGPESSGKTTVALSCVASAQKDGGIAAFIDAEHALDP
                     VYAKALGVDVDNLIISQPDTGEQALEIAEALIRSGAIDIIVIDSVAALVPKAEIDGDM
                     GDSHVGLQARLMSQALRKLTGSIKKSNCVAIFINQLREKVGIMFGNPETTTGGRALKF
                     YSSVRLDVRKIDTIKQGDKVIGSRTRVKVVKNKVAPPFKQAEFDIMYGEGISKIGDLL
                     DIAADVDIVKKSGSWYSYNDTKLGQGRENVKKFLEDNLDLTTEIDEKVRAFYNLNEEH
                     EESGTSVSKEIVEE"
     gene            complement(47576..48118)
                     /gene="pgsA"
                     /locus_tag="KOU88_001984"
     CDS             complement(47576..48118)
                     /gene="pgsA"
                     /locus_tag="KOU88_001984"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBK3211874.1"
                     /translation="MNLPNKLTLFRIFLIPVFVLIMLLNIPNKFLIACIIFIIASITD
                     ALDGKIARKYNLVTDFGKFMDPLADKLLVISALTCMIEDHLVSSWMVIIIVARELTVS
                     ILRAIAAADGKVIAAGNSGKLKTITQMVSIVFLLLGAQFENVLILNIGEILILIATLL
                     TLYSGWEYLYKNKELFMSSK"
     gene            complement(48105..49439)
                     /gene="rimO"
                     /locus_tag="KOU88_001985"
     CDS             complement(48105..49439)
                     /gene="rimO"
                     /locus_tag="KOU88_001985"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBK3211875.1"
                     /translation="MLKIALESLGCSKNLVDAEIMMGILNNKGYKLIGDFEEADVIIV
                     NTCGFIESAKQESIDTIINFAELKKTGNLKLLIVTGCLAQRYSEELKTEIPEIDAIVG
                     TGSYQNIDKILKELSEMHQIVSLNDIEFVFNEDLPRYISTPSYMAYLKIGEGCSNNCT
                     YCIIPKLRGKYRSRKFEDIIKEAKKLAESGVKELVVIAQDTTKYGFDLYGKERLSELL
                     EELAKIDGFKWIRVMYSYPESITEELIQVIKKYDNICSYFDMPIQHASNNILKLMNRK
                     TTKEDILNKINLIRSNIPDAILRTTIIVGFPGETEDDFKQLVDFVEEVKFDRLGAFAY
                     SREEDTPADRLPNHIDEEVKIQRRDTLMMIQQKISEELNDKKIGKTYEVLIEEQIEDN
                     VYTGRTQGDAEEIDSIVYVKSVDNLEVGEFVSVQINDAMEYDLMGDVLYELA"
     gene            complement(49433..50491)
                     /gene="mnmH"
                     /locus_tag="KOU88_001986"
     CDS             complement(49433..50491)
                     /gene="mnmH"
                     /locus_tag="KOU88_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBK3211876.1"
                     /translation="MSVIKIEKALKLDKVIFVDVRTEGEYEEDHILNAINMPLFKNNE
                     HNEVGTIYKMQGKHEAIQKGFDYVSYKLKDIYLQAAELALNYDNIVIYCARGGMRSGS
                     IVNLLSSLGVNVYQLEGGYKAYRNFVLEYLRHVMDTKNFVSVHGLTGTGKTDLLHLLD
                     EKGIDVLDLEGIAKNSGSTFGFITFDKKPPSQKNFETKLFESIFFSKENYIFVESESK
                     RVGSVTVPNEIFEAMTREGHHILLECDIENRVDRLCRDYIYDKDEGNILILKECINKF
                     RKRLGNKVVDDYIDLLESGEYKELVKRYLLEYYDPLYMHSVEKYKYSKIINFNDTQKA
                     LEDVIDLYESILEGESEC"
     gene            complement(50494..52905)
                     /locus_tag="KOU88_001987"
     CDS             complement(50494..52905)
                     /locus_tag="KOU88_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBK3211877.1"
                     /translation="MATKKKKKKKVNTLSFNAEYHNLITIFIGVFLLYSLNSNSMGWI
                     PVLMQNLFKGLFGGLSIAIPFIVIITGLLGFFDGNEYIYRLRKTKLYYIIILFIFVFY
                     GLLNAGTLPVDSPLKGNMFDDVMKLGVSGQGSGLIATTIAYYMSKIFGIAGGWLISIF
                     ALILSVMFIFNISIKDLVSNAKSKSKASKDSNLTFKDKIANMKKSAIDMMTDEVDDTT
                     INKKPGFFKGLMSKGLNNDDDEDEYFEEENSDGVDDKTIKIVGFNKAEDEYLEILEGT
                     QSMPELDVLKELQKATNENPVVDTKPEKKVDIAKPNLNIEKTQPMSIVAEPVNEDYSN
                     YKKPSIELLNKVNKKSDENGKKKVLKNASLLEKTLSDFGVEAKINQVTVGPTITRYEI
                     QPSPGVKVSKIVNLTDDIALSLAAKSIRIEAPIPGKSAIGIEVPNEEAQMVGVREVLE
                     SEEFNNFNSPLAMGLGKDVAGKIIIGDIGKMPHLLIAGSTGSGKSVCVNTLISSILYK
                     ANPDEVKLLLIDPKVVELANYNGIPHLLIPVVTDPKKAANALNWAVTEMNRRYKLFAD
                     AQVKDVTSYNEKAEEKLPKIVIIIDELADLMMASANDVEDYICRLAQMARAAGMHLIV
                     ATQRPSVDVITGVIKANIPSRIAFAVSSQTDSRTILDMGGAEKLLGKGDMLFYPLGAA
                     KPVRLQGAFISESESEKVIDFVKSQVKDGIKYEEDIIETISKVNTSKGSDEDEFLSEA
                     IEFVVESGQASASMLQRRFKIGFNRAARLIDSMEERGIIGASEGSKPRKVLISKQDLQ
                     NLEGE"
     gene            complement(53028..53762)
                     /locus_tag="KOU88_001988"
     CDS             complement(53028..53762)
                     /locus_tag="KOU88_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="HBK3211878.1"
                     /translation="MKDYREDNEKFDKDNCSEESSCEERECIKQFGTNEMPPQPPKDI
                     QCITIIGEIEGHFIGNPQKKATKYEHIIPMLYSIEESNDVKGVLVVLNTVGGDIEAGL
                     AIAELLNSTSKKVVTLVLGGSHSIGVPLATAGDYSFIAPTATMIIHPVRTTGLVIGIN
                     ETFEYFKKMQDRIIQFIIRTSNIKKDVLEKLMHEKDELVSDVGSVLIGKEAVDYGLID
                     EVGGLKEALKKLRELIKESEEEKNND"
     gene            complement(53875..55098)
                     /gene="dapG"
                     /locus_tag="KOU88_001989"
     CDS             complement(53875..55098)
                     /gene="dapG"
                     /locus_tag="KOU88_001989"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBK3211879.1"
                     /translation="MSILVQKFGGTSVESYEKMNEVCKIVKAYKKNDEELQLVLVVSA
                     MGRKGAPYATDTLINLCSAVNDEPSKRELDLIMSCGEIISGTILANLLNAQGIDSVFF
                     TGQQAGIITSDEYSNAKIKYINPKKVKRALDDGKVVVIAGFQGVTDDGEITTLGRGGS
                     DTSAVAIGKALECETVEIYTDVDGIMTADPRVEPNAKVLSFIDYEEVFQMADKGAKVI
                     HPRAVQLAKSGNITLAIKNTMNPTFEGTKIGSLCRHLEDNIEYEQERDFKVAVANKDS
                     VAQVKIKSAEEVFTEVLNEIEKKLITIDMINFFISEKAFVVEDADIKSLKEILDKFEL
                     DYEVNRDCAKVTLICSRIADEMSGIMSKVVRGLSKAGVSLLQTSDSNMTISCLVSEED
                     MHTAVHAIHQQFYLK"
     gene            complement(55108..55353)
                     /locus_tag="KOU88_001990"
     CDS             complement(55108..55353)
                     /locus_tag="KOU88_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlmC/YmxH family sporulation protein"
                     /protein_id="HBK3211880.1"
                     /translation="MNLSEIAGKEIVNLVTGERLGVIGECDLILDETTGGILALLIPK
                     EKGFFARRKDKSFLEVPWRNVKKIGNDMIIIEYEGYI"
     gene            complement(55388..56635)
                     /locus_tag="KOU88_001991"
     CDS             complement(55388..56635)
                     /locus_tag="KOU88_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBK3211881.1"
                     /translation="MYKTKILENGLTIIGEEIPYLKSITLGIWINAGSRIEEAQVSGT
                     SHFIEHMMFKGTKNRTSKEIASSIDNLGGQINAFTSKECTCYYVKLIDEHIDTGIDVL
                     SDMILNSKFDKNDIDKERLIILEELKMYEDSPDDLSYDLLVENIYANDGLGMNIIGTK
                     ESLYNITRESMLEYLNKYYIPNNAVISIAGNFNFDDMVEKIKSKFGHWEKKNLSIDIS
                     EAKFNPCFISKNKDTEQVNLAMCLKGIPFENDEEVYSMAVVNNIFGGSISSRLFQKIR
                     EEKGLVYSIYSSQTLYRKCGELGIFASMSTENLQDVYNLIKKEIENIRENYLTEKEIS
                     ESKEQLKGNYILDLESTSSRMMSTGKSMLLSKKVKTTDEILECINNVNINLIKKVVDK
                     VFNIENIGTCIVGRDVEKILHLD"
     gene            complement(56793..57536)
                     /locus_tag="KOU88_001992"
     CDS             complement(56793..57536)
                     /locus_tag="KOU88_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK3211882.1"
                     /translation="MIMMVLNKSKLKKIIILILVVLLVLSGGVMVLKLFNNKPVFNLF
                     NGVDLPYERGTKDKSGYVALTCNIDLGWETEYVESILETLKKENVKITFNVTGKWAEK
                     NKDELLKIKKQGHEIGNHGYKHLDYSTLSYEDNYEQIETSKKIIEEIIGEKTKFFQAP
                     AGSFGPETVKAAKALGYTSIKWDADTIDWKYKDQPEVIIDRMKKKDIKDSSIILMHPT
                     NATTKCIDDIIAIVREKGLKPGKLSDVFK"
     gene            complement(57802..59904)
                     /gene="pnp"
                     /locus_tag="KOU88_001993"
     CDS             complement(57802..59904)
                     /gene="pnp"
                     /locus_tag="KOU88_001993"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBK3211883.1"
                     /translation="MFEHKIFKMDFAGRELSVEIGKICEMASGSCIVRYSDSMVMVNT
                     TKSAKPRDGIDFFPLSVDYEEKLYSVGKIPGGFLKREGKPSEKAILTSRLIDRPIRPL
                     FPKGFRNDVQVVATVLSVDQDCTPDIVAMIGSSIALSISDIPFNGPTGSVCVGLVDGA
                     FVVNPNAEQREKSSMHLVVSGTKEAIMMVEAGADEVPDEVMLDAILFAHQEIKKIVEF
                     IEGIVAEVGKEKMPVELYHAGEEITQLVREFATDKMKKAVQTFEKLERMENMDRVKEE
                     TLAHFEETFEDFVGDIEEVLQDIIKEEVRKLIVHENVRPDNRKLEEIRPIWCETGMIP
                     RAHGSAIFTRGQTQVLNVATLGALGDVQKLDGLDEEENKRYMHHYNFPAYSVGEARPS
                     RGPGRREIGHGALAERALLPVIPSQEEFPYAIRLVSEVLSSNGSTSQASVCGSTLSLL
                     DAGVPIKDMVAGIAMGLIKHDGKVAVLSDIQGMEDHLGDMDFKVAGTEYGITAIQMDI
                     KIDGIDKEILQRALKQAKEGRIHILGEMRKTISQPKPELSPYAPKIVKMQINPDKIKD
                     VIGPGGKIITKIIDETGVKIDIEQTGEVFISGIEIDMIKKAQELINNIVVEPEVGKTY
                     KGKVSRIMNFGAFVEILPGKEGLLHISHIAHERVAKVEDVLNIGDEVEVKVTEIDEKG
                     RVNLSRKVLLPKPEHKNK"
     gene            complement(60029..60874)
                     /locus_tag="KOU88_001994"
     CDS             complement(60029..60874)
                     /locus_tag="KOU88_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK3211884.1"
                     /translation="MKIKLVCDSLCDIPDEISEKDYIEIVPLTVIFNDREYIEGVDIK
                     KEEFYKKVKEIKQIPKTSQATYMEFKEVFDKFITEGYHIICMTGAANASGTFQSAMIA
                     KNDVNENEKIHIFDTRNLSLGSGQYVIKACELLEEGLGFEEIIDELENTRSSVRLLFA
                     PYTLDFLKQSGRVPVATALIGNMLNIKPIFFFDNGEAKLVNKVRGIKNIASKLVDIIL
                     EMNEGSLEGKIVTIGCGDNLHDCEILKDEVNKRIKARRVLFTRGGVSICSHTGPDILA
                     ISCSN"
     gene            complement(61114..61371)
                     /gene="rpsO"
                     /locus_tag="KOU88_001995"
     CDS             complement(61114..61371)
                     /gene="rpsO"
                     /locus_tag="KOU88_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002843739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBK3211885.1"
                     /translation="MINKSEIIKEYGRAEGDTGSPEVQIALLTARINELNGHLKTHKK
                     DHHSRRGLLKMVGRRRNLLAYLKEKDLEGYRALIAKLGLRK"
     gene            complement(61475..62404)
                     /locus_tag="KOU88_001996"
     CDS             complement(61475..62404)
                     /locus_tag="KOU88_001996"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBK3211886.1"
                     /translation="MVIIKSIKEIANIKESVITIGNFDGVHKGHQVLIGKTVEHAKKE
                     NIQSIVFTFANHPVNYFRPNSTKNIISNDDKIKLLEDLGIDIVVIIPFDEYMTKIPAK
                     DFVDEILVKKLKAKKIVIGHDFTFARAKEGNVNLLKSLEHEFGFEVEVIKPIKINDVR
                     VSSTYIRSLVSQGDMANVKEYLGRNYKLEGCVIHSKHLGRTIGFPTANIDLKNNMLVP
                     KRGIYASIVHIGDETYFGATNVGYNPTVNGKTLSIETNILEFDRDIYGENIIVEFLER
                     IRDERKFNSIDDLKNQLYNDTNYVYENYVCKNK"
     gene            complement(62535..63440)
                     /gene="truB"
                     /locus_tag="KOU88_001997"
     CDS             complement(62535..63440)
                     /gene="truB"
                     /locus_tag="KOU88_001997"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBK3211887.1"
                     /translation="MNKIISILKPTGMTSHDVVSRVRKILNIKKVGHTGTLDPDASGV
                     LPICIGKATKVCEVILNKDKSYICELTLGISTDTYDASGEILKKVDDFKFSNEDIERA
                     FDTQRGEINQLPPIYSALKVNGKRMCDLVRSGRQSEITLKTRRVNIKDIKILSIKGNK
                     VMFYVECSKGTYVRSICHDIGEYLGCGAHMSFLNRTSSGKFDLDNSITLEELELFYEN
                     KTLDKYLYDIDYVLDSFNYVVLNPNAIKYYSNGGSIDDKRFLKNNFDKDDEFVRVYST
                     DNFLGLGKLSKHNNTISVKSDKMFI"
     gene            complement(63453..63758)
                     /locus_tag="KOU88_001998"
                     /pseudo
     CDS             complement(63453..63758)
                     /locus_tag="KOU88_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
     gene            complement(63876..64994)
                     /locus_tag="KOU88_001999"
     CDS             complement(63876..64994)
                     /locus_tag="KOU88_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3211888.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KSDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQYIKLPKLGMVKIRDKQVPQGRILNATISKEPSGR
                     YYVSLCCTDVDIEVFENTNNHIGLDLGIKEFCISSCGDFIENPKYLKKSLNKLAKLQR
                     ELSRKTIGSLNRNKARLKVAGLQEHIANQRNDFLQKLSTKLIKENDIICIEDLQVKNM
                     IRNRKLSRLISDVSWSEFIRQLEYKANWYGRKIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
BASE COUNT        20632 a        11346 c         6996 g        26062 t
ORIGIN      
        1 ggtgaatacc taaatgatta tatctattat ctcctgttga agaataaaat tttccatata
       61 tatctttaat aaatatagta ttgtaactag aaaatacagt atcaacatct ttctttatag
      121 atactttata atatggaact gacatatccc tataagattc atcagatata ccataagtat
      181 ctctacctga tgatatcaaa ttgttattat tatctatata aagtgtatta ttagctgtta
      241 caaaaacatc tttaacatct tccacactat ttgtattatt attatttgct atacttccat
      301 atccactaag acctccaaca aatagtttat tgtcatttgt taaaatggct gaagtatatc
      361 cattaactac tatttttttt gcatttataa tattattaat tactcgtatc ccctttatat
      421 cattagtctc tgttgaaaag aataccctct ctttttttcc tgtagtataa atcatattgt
      481 catttgttat aaaaaatgta gcttcacttc ctgctgtcac aacagatttt acattctcaa
      541 tatttatttt tgtaaatgta cttatacttc cttcagtaaa cccaaaatag ccatttacaa
      601 gtccacatac atagcatgta ttatcatttt taacaatgat tgatacatca ttacatagat
      661 atacatctct aacaccattt ataggtatac gtgtaaatat attcctactt gtagtatcac
      721 ccaatcctaa ctgtcctttt ccattattac ctgctccata taaaagacca tcattagtta
      781 ataatagaga tgtgtttcca tatacagcta catattttac attttcaaca tttattttag
      841 taaatatatt tctatttaca ttatctccta ttcctaactg accagaatta tttaaaccaa
      901 cagcataaca ggtattatca ttttttatcg caaatgcatg tttactattg tcagtaaatc
      961 tatttacatt tatagatttt atattatcaa tatttatttt agtaaatacc tttctattta
     1021 tctcatctcc cactcctaat tgacctacat catttaaacc aacactgtaa agcatattat
     1081 tattagttaa taaatatgta gactttgaat ggctatatat ttcttgtata ttagaagata
     1141 tttcactact gctattcttt ttattgtaat ttatcttatt atttaaattt aaactactat
     1201 taactgatat accatgcgta cccttagagt tatatccaca tataaataag ctcttatcag
     1261 ttaatattgc aaatctagtt ttatctctac ttaaatcata aggaggtata aatatatttt
     1321 ttatattttt cattaccttt ttataattag tggcattata tccatcttgt gtatctgaaa
     1381 catctagttc ttttgcactt tcagatatat tcccaaaacc atatagcgtg ttagaagata
     1441 aatacaatag agctttatat aaaaatatgg ctttatcaga ggtaatagga cctgaattta
     1501 tattagatgc tgcaatatta ttagatgatt gattgttaag ataattcctt ccatattgat
     1561 gtatataaga tgaacctcca gaaataagta aattatctgg attgacattt tttaaattac
     1621 ttgacgattc cccattatat aaataagcaa aagttgtaga agatgatgat tgtgtacatc
     1681 ttgtaggata ataattatat atataagaat caagatatcc tgcatatgaa attccctgat
     1741 attgaactct atagcttgaa tcagttggtt ttgtccatga agtaccatgg tatccagtta
     1801 gaaaagatcc aatgtttgta caaaatacag ttacatactc atatatgata atattattaa
     1861 ttttagtaat attattcgtg catgaaactc tactataact tgaccctgat atatttatat
     1921 aataccaatc acttaataaa cctagattta cattagatcc atcagaagta ctaaaaccta
     1981 acaggtaatt tgtatttata ccagttgcat ataccttttt ttcatcaact acaataaatg
     2041 ttgcattata tgaactataa gcatcagtta cattactaag gctaatctca gtatattgac
     2101 ttattaatgc attactaagt ccattaacat aacttgaact ctttccagaa gtgtatattt
     2161 gcttattatt agttacaatt aatgaaaacc agtttgataa atcagtattt ataacaactt
     2221 tttttacatt atctatagat attttcttaa atacatctga attagaagga agaacacctg
     2281 ctattgagtt actatttggt ccagaataat aacaagtatc atcattttta atgtagaata
     2341 ttcctccaga aatatttttt gatgctacta tagactttac attagagata cttaattttg
     2401 tcaactcatt taattgactt ggtaagtcag aacccattcc tttgtatcta ttatttccta
     2461 gaccatatac atctccattc cctaaaataa ccagagtaca ataaggacta aaaacgacat
     2521 ctcttacaga atgtatatct agtggaagtt caatatcctt tatttccatt tcttctttta
     2581 ataaagttaa tttatcctca gatttaatta aatttatata attactataa ctatattttt
     2641 cactatccat tttcttaaat tctacaatgt gcatatcatc aaaaaacgaa cctaattgtc
     2701 cataagtatt atctcctgta caatatgaat cattatttga atcaattagt atgctatgtg
     2761 ataaaccaat gaaaatattc ttagctacaa tattttttga atctataaat gaattatcta
     2821 tattctcaga gtaatttgct atacctaact gatatatatc attatttcca gcaaccttta
     2881 aagtaccttt gttatctata agcatagtgt taccatgacc acatgcaata gtttttatat
     2941 ttacttcttc tatcttagta aatagtgatg attgaagtgc atttccaaaa catttttcct
     3001 ttccacaacc atatatatca ttattatacg tcattaacac agtgtgttca gaaccacaag
     3061 ctatagtctt aacatcatta atagaaacta aactaaataa atctctatta ttcttatctc
     3121 ctaaacctag ttgaccttga ttattaaaac cagtagaata gcatttattg tcattcttta
     3181 ttataaaagc tgatttatta tatgaaaata cagcctttac attgtcaaca tctacttttg
     3241 taaatgtatt tacatttgca gatgctccat tagttcctag acctaattga ccatacaaat
     3301 tatttccagc aacatataaa gttccatcat tgtataaaag atatgttgat tgaagtccac
     3361 atgcaatatc ctttacgcct tttatttctg gaaccttctc aaatgtagaa actgttttcc
     3421 ctactttttc taatcccaat cccatttgac catctgtatt tatacctgcg acaagtaatt
     3481 ctccatctga agtaagtata actgcatgag attctccaca tgcaactttt ttaatattgg
     3541 tagatatatt tggtattttc gtaaataatt ttcttgttgt attgtcttct cccaatccaa
     3601 gttgaaagtt actattatct ccacatccat acaagatatt attatttttt agaccaaatg
     3661 tatagttaca acatccagta aaaaaattaa taaagtcata attatcatac ccttcatcaa
     3721 attcatcaac taccatattt ttatcgccaa agaaattacc tctttgaagt agtttagttc
     3781 ttttcattat aaaaacctcc taattatctt atttcatacg aatatttatt taaagttata
     3841 tctgtctgac caattgaata tgccctatta gattttgttt caacaaagtt attatccatt
     3901 tcatgtatat atctaactct atttgcatta aatggtagca ccacattctt aaatgtaaca
     3961 ctaccaagtt ctccagttat acactttcta tttaaatcta acttaaggcc ttctatagct
     4021 attatgtttt tagcattagt taaggtatca taccaatatc cagcttcatc tacatctatt
     4081 tctgactcta attctaagta tattaagata tctaatactt tttcagataa tttattgtaa
     4141 ctatttttta atacagatag ttcagtttgt atttgacctc ctattacatc atcaatagat
     4201 atatttttaa ttttttctac tacctcattt atagctcctg ataagttttt agcttctgta
     4261 gataagagtt cttcgccaat ttttactttt atttctttta tatttttatc aaacttatca
     4321 tctaaatctt gaatatcctt ttgagttaca aaaaccaacg tcgggtctac ttctaatgta
     4381 acatttgaag tattggacaa ttgtaaaatc atttttacaa ccaaatcttt aatactgcca
     4441 tcttcagcac gtggcttata cgtctctgga tacttaccta tagctattat attattctca
     4501 ttatccagaa cagcagcttc tcttatcata aatccaccaa ctgttcctgg taaaatagtc
     4561 tctataacta tccaattagg atttttttca tcaattctta gagaatttat atttccttcc
     4621 caaactacat tctttaaagc agtttgttcc tctgttggct cataatattc tccattacta
     4681 tctccaactt gaaacttggt taatccaaca agctctccta gtgcagttgc atttgctatt
     4741 ttttctctac caattttggt taatattata taaaattttt cttccaatta taccacctcc
     4801 gatttaggat aaactactac attttctaca cctgtatcat ttgcaatagc tatattaatc
     4861 ttacaattat tttcaatgca tttaatgctt aaaggataaa cctttatttc ttctctactt
     4921 aacattccag ctccacagtt tacaacagca ctacatttta taattggttc aaagtatgga
     4981 tgaactttta cctcttcact acataccata cctccaccac aatagaccat acttttatct
     5041 agtattattg gttctaaata gtgtaataag tgagcaggtt ttactctttc aatcatatcg
     5101 ctacaatcta aaagagtttt atagtcacag ttatttgcta taaaactcaa tacgaatgta
     5161 aattcatcac tataaacttt tatatctgtt tctgattttg tatatgcctc acatatactt
     5221 tttataactt caatagtact agtacctctg cttctcattt tagcttttat attgctacgt
     5281 cttgtgtcaa aatcaagttc ttttttttca atgcagagta tgtcttccca catatctaat
     5341 ccccatgttg cagtgtcaac aaataattgg ttaaaggtat catcaatatc ttctttaaga
     5401 atatttaatt ctgtatcgta tgcaccttgt atctcctcta caatgtaatt tctatcaaat
     5461 gatggtagtt tatcaattag cttcattgat tttccacctc actaaaatta acagttgtta
     5521 cactaggtat tttatcttca ttaatagtta tattatctgt acttccattt ataagtagct
     5581 tacttaaatc gtgtacacca gtagtattta taagtattcc cattactttt gtatagatta
     5641 tttctcctct aatatctcta aggtatgtat ttatactttc taggaaagat tcttttacat
     5701 tgtctaatgt atatccatct tctagtttca ttactgcact tatacttatt tctattggta
     5761 atggtgtcac aactgttata gttggtccaa taggcttctc ttcatctata tgttgctgac
     5821 acctttcaat agtttctgta tcaacagctt gattattttt cccaaatatc aagaccttaa
     5881 ctgttcccgg accatcccat cttggataaa ccttaacatt atagactcca tctacttcca
     5941 aagcccattc ttcatagtga gctttatttc cacttgtagc ttgatttctt tggattttat
     6001 aaaatctttc ttttagctct tcatctgtct ctatatctgt accaccttca aaacttcttg
     6061 tgttagtaat ctttgttact ccagatatat tatcaactag tttaaattca caatttgtag
     6121 gtaaattata tttcttacca acttccagag cttgaactgg gctattgtca ccttcttcac
     6181 taccaatagt tacatctttt attactacaa atagtaaatc tctatatgat attactgtgc
     6241 cattatttat tacagtacct ttctctccaa taaattcaac ttctccattt gactctgtac
     6301 ctaactttct atatacacca aattcattga ctcttttatc aagaaactgg ttatatgtgt
     6361 cttgtataaa agccatttta tgtatctttg aaagttctag atatatcttc gaaagttcta
     6421 gattatttcc agataccatg ttgtttagaa aagaaccttc tcctttataa atatcaagat
     6481 taatattttc aagagttcta ttttttatta cttcatatgt ctggtcacta tacatttatt
     6541 tccacctccc catagatagt ggatactttt acatttgcac tcaatacgtc tctgttaaag
     6601 ttagcacttt ttacgtttac ttctaatata tatggattta ttagaagggc ctcttttatg
     6661 aatctactag cttcactttc tgtaagacct tttgtatatt tttgtcctat tagttctgaa
     6721 agctctgtcc catattctaa agagtatatc tcatgttcat atctatttgt ctttatacac
     6781 ttgtatatcc aaacttttaa ggcttctttt ttttcaatta ttttaaagtc acctttttct
     6841 aaaataggtt catctttttc aaaatcccat gccacttcac gaaagattgg caattcttct
     6901 gttttaggta agatataatc ctctgggaca cctataaaag gaaatattgt actcattata
     6961 agctcaccaa cttacttaca acagcaaatt tttcgcctat tctaaacatt attaccatat
     7021 ccccagattc aaagttatct ataaaaggat tttttacttc atgctggtgt tcttgatttg
     7081 tttctgtgtc aaatgtttct agctgtctat caatcatcca actatctatc aaaatatctt
     7141 ctttttctaa tatgatgtta tttgtctcta tttttaaatc tggtaattta cttttaattt
     7201 ttccaataaa aaaagaaggt tgattatgat actttccttc ttctcttatt atccctataa
     7261 attcatttat tggattagcc attatatcac catcctttta taatactctc ctagctgtat
     7321 taaaatctct tctactactt aacttactta ttttaactac atcacctttt tgtggagcat
     7381 gtaaaaattc tccattacct atatataatc caacatggct gactggatta tgaaaaaata
     7441 ctaaatctcc tgcttgaaga tttttttgtt ctactttctt gcctttttta gattgttgat
     7501 ttgacgttct tggcaaacta acattaactt ttttaaaaca atagaccatt aaaccagaac
     7561 agtcaaaact acttggtcca tttccacccc atttataagg tttacctaga tgtttttttg
     7621 cttctgatat tactatttta gctttatcag atacattacc agaataacca ccaataataa
     7681 tttttccttt tcttcttcca aatttactag cttcttcaac atttccaaat aaaatatcta
     7741 tatggtatgt tccattcttt tctatagtta ttgcaggtcc tacgtcattt actttataga
     7801 ctccatcacg accagaaact cctgtaatta cctgtatttc atctccatag tttaataaag
     7861 gatgtttatt taaaaactct tttgtataat aagtttgctc atatttacca accataggag
     7921 cagcgcaagt ttttttagat gggtcaagtt ttttctttct acaatctgta tctccacctt
     7981 cttcttttct aggacagtaa gctgtaaatt ctgctgtaaa ctcttttcct cctgcataat
     8041 cttctccccc taaattactt tcttccttag gttcatcctg tcctgctgac ttttcatcca
     8101 taagattttg aaaattaagt tcaagctcaa tttgatattc tccattttgc caagtatgtt
     8161 tgtctgtatc tatataaaat agtcctacaa gctttgtata agaatcttta acttttactc
     8221 ctctaccagt tatacaactt acatctccat aacctttaag agaacagctt ttttctatcc
     8281 cattaaactc gctatcaata tctacatctt gattttcttg ttgctgaatt actttttgca
     8341 ttattacatt tacttcctta aaaatttcat tatctatttt ttcgctaatc ttgcttccat
     8401 actggtctac cactattact ttatttttta cattttccat gctctccgaa aaggtggtat
     8461 ttataatatt aaatccctct tcaaacataa catttaatgt aacaattcct ttttcaataa
     8521 cattaaactt atctaaattg gcctctatca tatacttttt ctttgtcttt ttacttgctt
     8581 ctgtatatgc actcattatt gtgtcataac catttactcc tataaacatc tttgtatact
     8641 tgacattggt ctttgctatt gttccaactg aaagcctatt ttcagcaaat acttgctttg
     8701 ctatgtcttc aactaactta tctttaaaat tgtatgacac ttcactttgt gtaagtaaaa
     8761 atcccatatc tttagataca aaactaattt cattactgct tgaatcttta gacctattaa
     8821 ttatcattcc tctaaagagt tctttctcat ctacatagaa acagactgta ctagctattg
     8881 gtatatctat ttgttggaaa tttacatcaa atgatgattg tattattgaa aactctagtg
     8941 tccttgatgg agatttataa tcacctgacc atgatacctt gtctactatg tcagttatgt
     9001 catatatact tccgtttttt atgtgtaccc aaatcttaat aataaaaaat cacctgcctt
     9061 ttcatttaat tctataagca gttatttata acttattatc tataatagtt attgttttgg
     9121 agttactttt ggtatcttta ttcttttata ctcttttaaa tctaatgtaa aatatacatc
     9181 tcgagtccca tctctttctt cataactaaa cccttcaatt atgacttcca tatttatatt
     9241 tgtttccgta attgtaaatc ttaatataaa accttccttc atccattttt ctatcttatt
     9301 tacacaatca tatggtgatg gaaaacctgt atagtcacag aaagtatagt ctttatttgg
     9361 aaaaaaactt gatattgaaa tgcttttaag agctacacca ccaaaagttg ctatttcacc
     9421 tattttgagt atactagaag agtttacagc agcttttcca ttaatactaa aggaagatgg
     9481 aaatactgga aatctaaatc tatcttcagc ttgtctaagc cacatttcca ttataagaca
     9541 ccccctaact gtgccaattg gatacttgca actaattttg atgttatctt ttctatatca
     9601 gcttcttctc taatcactat tgtatcagct aacttagcta tgtttatatt tccaccattt
     9661 tttctgcttc tatattgatt tgcttcttgt ttagttaaaa ccatttcacc ttcatggagt
     9721 ctggtttgat agtcattata aggaacatag ttcaatccaa atgcattatt acctttctta
     9781 cctgaataag ctttaccaga atcaccagcc tttgttccag catatggatt atctttgtaa
     9841 ttttttttac tcttttccac tagatttaaa actgttcctg tgatgcttcc attttttatc
     9901 ttattaatca tagtttgcca ccacttgcat atatctttaa ctattttaca tactttatct
     9961 aatatgttaa aaaaagctcc caatattggc tctataattt tccatccagt ttccaacaga
    10021 ggtcctaagg tctcccatac agttttccaa ataacaccca gtgtctctat aaaattgttt
    10081 atttgaggtg catattcacc taaaaaagta aaaattcttg tgataatagg actaacagct
    10141 tcaactacag gtccgattag ttggaatgct gtagttacta ttgtaccaaa tatacttatt
    10201 aatccttgtg caattggtga tttattgttt atactatcta gtaaattatt tactaagttt
    10261 actactggaa gtaatgaatc tattaatgct gtaaaatcga tattttgtaa tagtgtactt
    10321 cctgcgttaa caattgcttt tggtgcattc cctatcattg ttgctgcatg attttcaaaa
    10381 cgttcttgct tattttcaac catcatttta cgcttttcag cctcattaga aattcgatat
    10441 tgagtagaat cagaaaactc ttttccattt tttacacttc tagattgcat ctggtcatat
    10501 ttgttgccaa taattatctt accattcatt acattgccta ttttaccagc cattttttca
    10561 gataagccag ctaaattgcc taatccactt tctataaaag tttttatttt ctttagtcct
    10621 tgacctaaaa tatcatcaaa aggtttaaca atactcttca agccattgtt aatgcttgtt
    10681 tgagctcctg atattatacc tggtattgta ttactcattt ctttagctaa ccccatctgc
    10741 tttacactta tgccttccaa tgcttcatca aaagttttat aattttctcc taccagagta
    10801 ttaagagatt ccatgtttcc ttttgctgca cttaagaaag ctgctgatac atcttgttca
    10861 ctacttgtat tcatatttaa agctctaaca tctaccatag cttgagttat atctttttct
    10921 tttttgccac cagtaatatt actaatcatt ttagctttag ttcccattgc aacaacatct
    10981 tcagggtcaa aaggcgtatc atttgccatt cttactaaac tgccataata atcatcaaca
    11041 tctatttgat taacttttcc agtatttctt ttcattacac tttctagaac aactttctga
    11101 ttttgttcct gaccaagtaa atcaacaccc tttttcacag cgacacctat agtagcacca
    11161 tttgtcaaat cagatatctt cccttttatc gaaccaagta ttccacttgc catatccttt
    11221 acagctattg caccactcca taccttacct gcaaataatc tcaatttggg aaatacttta
    11281 cttataatgc cacttgccat atcttttata gctattacac cactccaaaa agtattttta
    11341 aacaacatta acttaggcaa aattctaccc atagcactac tcaccatatc tttaagatta
    11401 atacttcctt gataaggacg tttctctact tgttttaatt ttcccaagat actacttatc
    11461 actctcttag tcatatcttt tgcttttatt acgatattcc aaatcttgcc accaatcttt
    11521 tttaaatttc caagtaattt atttttagtt ttttctactt catcactttt agctttaaat
    11581 attaatataa tcataatatt tgaattaaac tcatttttct tttgaatcaa cttattaaaa
    11641 taatcaataa tcatagctat agttattgct agtctcataa tacttccatt taaacttcca
    11701 ataactcctg aaacagcatt tatgctagaa cttaattttg tcatagttga acttacacta
    11761 ctagcagtag tttgaacttt tcttaacgag gaatttaaac tgtttactct attacttgca
    11821 cttccaatag aattttttat gctactagcc attacattag tggaaagtga aacagccaca
    11881 gttgctctcc taaaattatc agttactgat ataatttgat tcatttttgg tgtgtaatta
    11941 tctgtaaggt acatatttat accttcttct ctcacatttc ccattacata ccacctcctg
    12001 tcaaaggaca cactccatat ccatgtttca ttttttcaac ttcttcctca atttctaagg
    12061 cgaaaaaagc ttcaataagc tttaattcgc ctttatccat tgcataaaaa agggacggtc
    12121 ttataccttt tttcttccaa taatagtaca ttattgtagt cctggtatcc gtccctatta
    12181 gttttttacc tcttctatca ctgcattttt accataaccc ataacatctt gaagtattct
    12241 atataagttg gtaatttcac ctggtaataa caattttctt gctaattctt ttggtgttgg
    12301 agccttaaat ttatccatta gctccttatt tttaaataaa agctttccat ccaaatcaca
    12361 aacaccttct ataattgtaa gcatctgcat ctccggtaag tctatatccg ttttcatatt
    12421 ttcatcaatt ttaagacaag tattttgtat ttcttcatct ttacttattg ttaaagctct
    12481 acacattact ttaaattcct gcccaaatat agttgataat ctcttaagtt caactatagt
    12541 acttggtctt tctaagtttt ctgtatctgc atttaaaagt aaatctacta tgtttatatt
    12601 ttttaataat ccattttcac tcattattat ttgctccttt atcaatcaaa ttcaatcaac
    12661 taactttttt acttattaac tatctgaatt tattaagtat atatttacta aatatcagta
    12721 taaaaccaaa tataaaacta aatataaaac taaattatat caagaaaatc atactcagta
    12781 aatgtgaaag gtgcttctat ctctcctttt acgccaacct cccaatcagc taaagttaaa
    12841 tcatcaaatg ctatattctt tactgctatt ctttctgctc cataagaatc tgggtcattt
    12901 aatttagata tagcaacaaa tctaggttca gaacctctct ttatcttttc tccaattaac
    12961 ttgtgcattc ttgaactaac atggtataga gttattgagc cttttccttt atatcccata
    13021 tactttgtat cagtacccat ttgacctgct attataatat cttcttttgt aaattccatc
    13081 tttgcttgaa acttctttac ttctgctact ttgtttccat caagccaaag ttctccccaa
    13141 gtaccactca ttacatttct agcttccata tttgccatat taataatcct cctatatttc
    13201 tattgataaa tctatatctt ccatagcatc aagtactttt atttttgctt ttaaaaatac
    13261 tttagaacct gtgttagctt cttttatttc ttgtaatgtc atataagata aatctactcc
    13321 ttttgatttt aaatacgatt tttgtgcttc aaaatctatt tcaacagtag aatcagattc
    13381 tataagtgct gatttttcta attcttctaa ataacttttt atagctacta tcaataaaca
    13441 tttgttgtca taactgttag taacctttcc tatatagtca tctattatca cctttcttat
    13501 gtcactatgt ataatatcta aagtgtcaac tatttttatt ttctggaaca tttctccttt
    13561 ttctgctgtt aattcagtta aagaatttac tcctctagca attcttatag ctcctgcttc
    13621 tttaataagt ataagctctc ctttattaac ccttgattct gcatcaactt tcgtcatctt
    13681 aggtatatcg actacatcac taagtttagt ataagttact gattgactta aaggtgtacc
    13741 tgctataagt ccagccaccc tacttgtaaa ctcatcaaca ctgtatttct tttctccaac
    13801 taacacatct tctgtagtaa aattaattat cccttcatga tttcctacaa cttttcctaa
    13861 tacagcttta accttaacct tatctatatc tctaagttta attatccaat tttttatagc
    13921 agtcttatca gcttctactg cttttggcat acatagataa ttaaattcct tagtctctaa
    13981 aaaatctaat gcagtttgaa tatctgcttc tccttctatt acataaacta ataatttatt
    14041 tggagtgtta acatttccca tcaaagctaa atttatatat tctttatttt cagcagataa
    14101 atcaactggt atatcctctt tttcatgtat ttcattaaga cctagtgcct tagcatcttt
    14161 aagcaccatt gcaattattc ctctagctga acgttcttta acagttgtag ctagctcctt
    14221 aaatgatatg ttgatacttg gtaatcctat agccatacta tcactctcct aaatttaaat
    14281 tgatttcttc catattttca tatactacat cttcttcata tacactatcc agatagttta
    14341 gtgtaaatgt aaagttcaat acataaattg actcttcttt tttaatactt tgttctagct
    14401 ttgttatatt taattttctg tctgttacct ttatatttct gttgaatagc ttatttaatt
    14461 catctgaaat ttcatacatt ctaatactct ttgactgtgg ttttggtaag tattttatag
    14521 agataacaat atctttatta ttcgtattta acattatagg tgtacaaata actgatagta
    14581 tacttacaaa aaaacaagac ccttcagagc cttgcacact ttcatcatca ataaaaatac
    14641 tttcagtaaa gttttttttg agaatctcaa taattgtttc taatatttcc ttgtatttaa
    14701 gcaaataatc accacactat cactaaatat tcttgcttaa tctgataatc ttactataaa
    14761 tgatataagt catttttaaa tatatatctc atttattcct gtcaagtatc ttctatattt
    14821 ttaggtaata ttattctttt caatctatca cctccttcaa tatggatttc tttcacaata
    14881 acattatctc acatatttta ttgcctattg ttgcaatggt gtatataaag tgttgtaaaa
    14941 ttgtcctatt ttttataata tctcactcaa tttaaatatc atctttttct ttaaattgta
    15001 gcaagatgtt ctatctaagt gtagtttcat agaaatatat gtcatattgt tttttgtctt
    15061 actattataa aaaagattaa aaaattccat ttctatatca tttagacacg ttagagcatt
    15121 ttctatcttc tctttttcta tttctatatc ttctttttcc atttttaatt ttcttaatct
    15181 ttcctctctt tttaacacct cattttccac agaagagctt atgttatatg tgttactagt
    15241 cttttctgta tataccattg ctccacatcc agagtattca ttctcacatc tttttatgtc
    15301 caagttaata ttctttatct ttatatccaa atacttataa ttatgtaatc ttttatctgt
    15361 ttctttaaat aatatatctt ttttgttttc catagtactt ctcctttttt atatacttat
    15421 tattagcttc aaatttacaa taatctcttt agtgcacagt tttttactaa tctcacaact
    15481 ttcaagaaca tattgttcta tgactgtata aaaaaaactt cttctatatt ttgttctaaa
    15541 atactagaaa tcttcttagc cataagaagt ccaggatttt ttatgcctct ttctatttga
    15601 gatatataat catttgtaat tccagccttt ctggcaagtt gaatttgtgt catacctttg
    15661 cattttctat aatatttcaa gttattttta aacattgttt tatacctcca ttactattaa
    15721 gaatattttg ttcttcctca cttagattat atagaattat ttgttcttta tcaatatatt
    15781 ttagaaaaaa atattctttt atattttatt agttttattt tttagaacaa tttgttataa
    15841 tctatacata aggtggtgtt ataatgtttg ccaaaagatt aagagaactt agaaaggaat
    15901 ttggattgac tcaaagagaa cttggagaaa aagtaggcgt ttcccaaaga gtcttagggt
    15961 actatgaaac agaaaacaga tttcctgatg aacacatttt aaataaattg gctgatgtat
    16021 ttaatgtatc agttgattac cttcttggaa gaaccttagt taaggaaaat attgatacag
    16081 tagctgcaca tagaaaaaat ccacatgaag agttacctga agaagcacaa gaacaactta
    16141 atgattatat agaattttta ctaaataaat ataaaaaaaa ataaaccata tgatgagcag
    16201 tctatttttc tgctctttta atataattta aaggcaaaca tacattctat tttaggggga
    16261 tttttatgaa taatttggat aagctttttg aattagcttc tcaagaaggg ataataattc
    16321 attataccac ttatattgca ggtgatttag aaggactata tataaacaaa catggtatta
    16381 aaattatatc attactcagt aatttaaaac aaaactcaaa aaaattaaca tccatcttag
    16441 ctgaagaact tggacatcat ttcactagcc ttggatacta tgtatcctct tataacgatt
    16501 attatacaaa aattattata gataagtgcg aaaataaagc cttaaaatgg gcttgtgagt
    16561 tcttaattac tgaagaagat ataataaaca taattaactc tggcatcacc tgcgtttatg
    16621 aaatggcaga catacttaat gtggatatta ctttctttca aaaaagatta gaatttttat
    16681 cattaaaaaa acagtcttta caacttggaa ataataaata tttaatatta actaatttgc
    16741 cgtatttcta catatttgat ccaatttcat aataaaaata gtagtaattt taactggctt
    16801 aacagtaaaa tctatatatt tattttaaca aattttggtt tctataaatt caatattaat
    16861 atataataat gatatcatat tatttaaaat tctaaaaaca aatatatgct tttgttaaga
    16921 aaggttgttt gatgaatgta taaagaaaag ttgtttgata attattttaa gttcttagca
    16981 ctattatttt ggccaattat gtggtataag tggatagtaa tttcaaatgg tactcttgaa
    17041 aatatgttat ttaccatata tgcaatcgtc gcaattgttt tcatcatttt atattcggtg
    17101 tttatgataa aatataaaga cattacacaa atagatttct tttacaagat aagtactcta
    17161 cttgctttta tatttacact ttttagcttt ttaatatacc caaagagttt atttttcttg
    17221 tatttaaaga ttatttttac tggaatatac ctttattatt caatagtaaa aactcttaaa
    17281 tttaaagatg acgaaggtgt agtgggtatt atgagctcac ttttattaat tgtaataact
    17341 ttgttctact aaatttaatt ctatttgact taatatggct ttaaatatta gacatctaca
    17401 ttattttctg atattattta agatggtagt cttatattaa taatgaaata cactatgaag
    17461 gagttaacta ttatggaaaa aaaagtttta gcaacagttg gagaaaaaga gataactaat
    17521 attgatattg aaaatgcatt aaaatcatta gacccttatc aagctatgca atttaaaact
    17581 gaagaaggaa aaaaacactt attaaatgat ttagtgaatc aagaattatt cttcttagat
    17641 gctaaagaag aaaaattaga tgaagaagaa atatttaaat tagaaatgaa aaagatagaa
    17701 gaaaatgtat taaagcaatt tgctataaat aaagttttat ctagtgttaa tgtaacagaa
    17761 gatgaaaaag taaaattctt tgaagctaat aagagctctt tctctaaacc agaaagtgca
    17821 actgctaaac atatattagt agatagtgat gaaaaagcta aagaaatact tgctcaaata
    17881 aaatcagaag aaatatcttt tgaagatgca gctcttaaac attcttcttg cccatctaaa
    17941 gatatgggtg gtgatttagg aacattcggt agaggacaaa tggttcctga atttgaagaa
    18001 gctgtgttct ctatggctaa aggtgaagta agtgaaccag ttaaaactca atttggatac
    18061 catataataa aattagaaga ccttcaagaa agtacagagt ctacatttga tgaagttaag
    18121 gctgaagttg aaaaaagttt attatatcaa aaacaaaatg aagtttatgg aaataagata
    18181 aatgctctta atgctaagta cggaaacctt gtaaaataca acgattaatc ataaggtcat
    18241 atataaaaaa gctgtctttt cacaatattt attagaaaag acagcttttt atattaaagt
    18301 ttaaatattc agtttcatat tatcattctt ttattgtaaa gaactcagct taaaagttta
    18361 aataagattt ttaattatca ttagctaaat ttttatatcc acgtattatc tcataacagt
    18421 aacctattac atctcttctt tttattatcc caataaatgt gtcttggtca tctataacag
    18481 gaatgaaatt ttgatttaaa gattttataa ctaaatcttc aatatctgcg ttgatggaaa
    18541 caggagaatt atccattttt ctatttatat ctgtcactgg aacatcttcc aatcccttta
    18601 agtccagatt taaatcattt tttaatgtcc ataaaaaatc accttctgtt atagttccaa
    18661 catatttacc atccttactt attattggaa ttgcagagta tttgtgatat tccatttttt
    18721 ctagggcttg ccttatagtg tagtcttcat atatatatgc tacttcactt tttggtgtta
    18781 gaaagaataa tatgttcatt acactaccca ccgttactga aaacttataa atattactca
    18841 atatttataa tgttactttt ttgcagtaac tttctccttt cttattttct aagtattctt
    18901 aatactatac gctgtaacaa gcgtttttcc tttgctcatt ttaatcttat tatgctttat
    18961 taatattttt atatggtcta tcagtatcac ttattctctt tttagaaaat ttactaaaaa
    19021 ttaattgact taaacttagc cataataatt ttactctaca ctattaattt taacatattt
    19081 atctcattat taatgatttt attttaataa ttttaattta ttttgctatt aattttattt
    19141 acaaaaactg aaaaaaccgc taaatgatta gcggcttatc tctcatatta ctagaacact
    19201 aatatatatg aatttttaat tataatctaa ctacgttagc agcttgagga cctttagctc
    19261 catctactac ttcgaactca acgctttgtc cttcttctaa tgttttgtat ccatctccag
    19321 ttatagctga gaaatgtacg aaaacatctc cttcaccttc tacagatatg aatccaaatc
    19381 ctttttcgtt gttaaaccat ttaactacac cagttttcat taataaatcc tcctaaaaaa
    19441 acacaaatat ttagctactc ttttctgtaa ccttattact actctatcat atatagctat
    19501 gtttgtcaat tattattatt tttatacatt aataatcaat ttttttactt tataatttta
    19561 aatgattatt atcttttaca ctttattttt ctttataatt ttttaataat ttatttttat
    19621 tatatggaat cttatggact tatcactcca acctaaatcc catggcacca acattctatc
    19681 agtattatga caagttacca aaggataccc tcttgagtct aatcctgtca ctgtcgaaac
    19741 atgtgttatt ctgcctttct tctcataacc aacaaaatcc cctggacgta aattataagc
    19801 ttctttgtat acttcttcat aggaaccttt agcaattaat gaacctcttc cactatacag
    19861 tgcataattt ttaaaagctt gtgcatttac ccatgctttt gtacctgctc tctcgctata
    19921 attccaaatt gagttctttt tgaaccttcc actttcaaac attatctgtg atgcaaagtt
    19981 tgcacaatct ccaccttctg gattataatc cctatagttt ggattaaatt tcataccatg
    20041 ttcttcatca gctgcggctc cacagtattt atgtgcataa tctatagcct ttttttgttc
    20101 atctgtaagc tgtaactcta caccatcttg ttgcccaata tagtttctta tatcctcaga
    20161 ttttatattt tctaaattta aagagtctgc aaaagggtct gtgtaccact ctttagttat
    20221 gacatattga ttatctataa tttttacatt tagataatga tatgtaccta ttctaaaggc
    20281 attttctttg tccttttgat tttcatatga atacttatat tcagtcgata ctgaacagat
    20341 tataccatag aggtcttttt ctttttcttt tattttttta atcttaaccc ttgtctttat
    20401 gtctttaaat tttacacctt gcttactaga ccagttttct aaatacttca tcttttttac
    20461 ttcattttca taagcccata gaccaaattt tttatccgtc tcataaagac cttttaaaat
    20521 attttcattt ttctctaata ttgccttatt tctgtagtca aataagtttt caagcaatag
    20581 tttatattgg tcttttacat catcaccttc aacatttgca gattccatga ctttttcttc
    20641 catatttttc atacttaaat cattgattaa aaatacacct gctgtagtag ctaaagacaa
    20701 aaatacaaat gccattatac ctttgatgta cttattctta tttttcagta ttttcaaagc
    20761 tacacctccc aaatagtaca ccttacaaat caaattacaa agaatattct gtcacatata
    20821 gtaattttca tatttaataa ttctctattt tattatgtcc aatattaaaa attaattgta
    20881 tcaatacact gtttttttta caatttttta ttttataatc tacttttttc ttttttttat
    20941 agtaatatat atgtatataa atattttggt atcattataa ttaatacata ctaatggagg
    21001 gttttttatg caaaaaaaag tcgcagcaat taatgactta tctggaatag gaaaatgctc
    21061 attatcggtt gctataccta tactttcagc attaaaggtt caatgttgtc catttccaac
    21121 ggccatactt tcaagtcaaa ctggttatcc tgaatttact ttcttagact ttactgatga
    21181 aatggtaaaa tattcaaatg tttggaaaaa tttaaaagtc aattttgata gtatatatag
    21241 tggttttttg ggttcaaagc atcaaattga gatagtggct aattttataa acgattatcc
    21301 caatgctttt atcgtagttg accctgtgat gggtgataat ggagttatgt atccaatatt
    21361 cacagaagaa atgagacagg aaattaaaga attagttaaa cattcagatt taactactcc
    21421 taatttaaca gaagcttgtt tcttaactgg aaatgattat accaaaagcg attataatag
    21481 agatgagctt atacatattg caaaatctgt atctgatttg ggacctagca aagtcgttat
    21541 tactggtata ttagaagatg ataatatatt aaatttggct tacgatagag ataatgacca
    21601 tgtattcttt acatcagtca aatataataa ttgttcttac agtggaactg gagatatatt
    21661 cacatctata ctttgtggta tgttagtaaa taaacatgat ttgggagtag cggttaatac
    21721 tgcaacagat tttatatata aaactataaa ttacacatct caatttgata ctgatagaaa
    21781 tgatggagtt atgtttgaaa actttttatc agatttaacc aatatataaa atcaaaaaaa
    21841 ctatccattt tataaatacc tataaatcat aaaatttagg tatttacaaa atggatatta
    21901 tttactaaac tattggtatt tcaattgtta ccatagcacc accagttttc acagaatttt
    21961 caatacataa agtcccatta tgtttttgta caatattatt tacaatatag agtcccattc
    22021 cataatgaga tttagaattt ctactcaaat ctcctgtata aaactgttct gtagcttttg
    22081 acaaatctgc tttagaaaaa ccacttccac aatctgtaac tacaaatttt aagtatttat
    22141 tacgtactga tacacttatg tatagtttac tctggcttgg tgaataatct atagcatttg
    22201 aaattatatt cataatagct ctgaataaca gttctctatc tatagttata tttttaggca
    22261 aattatcctg tttataaaac tccacatcta agtttttagt actagctaat gcttctattt
    22321 gcactaagac atcttttata aactcactca tactgattgc ttctttattt aatatatagc
    22381 cattctctgt ttttgatata tctattaaag tattaatata tttttctatt tgagtgacac
    22441 cctttgagat atattccatg tattctaata actcaggatt ttcatttatt tcaattaata
    22501 agtcagtatt tccatgtata attgttagtg gtgtttttat atcatgtgcc agtgcagata
    22561 tctgttcctt tctattttct tctagcatcc attgtttttc taaagaatct tttaacgcca
    22621 acttcatttt atccatagaa aaaaggacat tattaatttc ataaatttta ctagattcta
    22681 caacaaaatc taaatcctgt tgttctattt tttctgtagt attttttaaa agctccattt
    22741 caatattaaa tttcttgcca aatacttttg ataatataac aatttcaata aaaaatatta
    22801 tactaaaaat aatcataccc aatgtctctg gttttggtaa atatgctctt aaaattggag
    22861 aactatactc tgatactatt ttgtatttta ttataaaaac ttcatctttc ttaaaaaact
    22921 ttatataact ttctgaatat gcatgccttt cttcaatatc tctcattaaa ttccatactt
    22981 cttttgattc ttttttatta aaggtacctg aaattaaatt cccatctaaa gtataaaccc
    23041 catactcata tatacttgga attatatctt cagttacttt ttcacttgaa ataatctgtt
    23101 ctttatattt attaaattgt ttttctgcat aattagctgg taaaattaca cctgatgata
    23161 ataatacaga aaatgataac attaaaagga gtacaattga aattgtcata ataaagaata
    23221 aagataaata ttttataaaa atagttctta acttttcaac ttttttgttg ttagattttt
    23281 tacctccaag catttgtacc ctgtcctcca atagtttaat taattcataa ttaataccta
    23341 gccagttttt tatttgatta ttttatatct ttttattgct aagttatatt ttaacataat
    23401 aatataaata aatagtcaat ttttactcta ttcttctgat tttttacctt cccatttaga
    23461 aaaccaaata cataaaatta caaatgctaa aattgttaca aaaccacaca ttaaacctgt
    23521 tgattgatat gcttttattg attcaacctt tatatattca accgttttag aacttgaaaa
    23581 agacgaccaa atagttataa atctaacacc ccatgcacaa ggaaaatact gccaaatagc
    23641 agaacccaat ccagttaata ataatgctga aagtaacatt tcaactatac ctactccaat
    23701 tgatgttcct tttccgaacc ttaaacttaa gaataaatgt aatatgtatt caaataaatt
    23761 acacccaatt aaaattagaa ttgaaatcat ataaaagctt gatgtaaagt aagccttaga
    23821 tataccaaat ttaaaaccta atacagacac taatgttgct acaaaaccaa gacatactaa
    23881 gattatatat ttacttataa gagtaagata ttttggatta gatgttgtta acatatgttt
    23941 ataattccct gcataatatt cttgttcaac aaacattgaa cacacaacac ttgacaataa
    24001 aggaaaagct attgctataa cttgtaaata tgctactatc tttagtatat tatcagctcc
    24061 tgaaacctta taataccata aaaacaatcc catccccatt aaagcaatgc aaatgtgcat
    24121 tagtattata aaatttctct ttaattttat taaatcagaa caaaatattc ttattaactg
    24181 tctcatatta cttcacctct ctattattga accaaaccct tgtagctaaa gcaaataata
    24241 caaataaaac aatagatatt aatactcctg gcaaaataac agcattattt aaaaattcac
    24301 ttccctctgg tacaggaaga ccatttggca gaatatgcaa tacaacagcc attaatcttg
    24361 aaggaatcga atatggaaat atataccaca tttctgtagt tgagaaaaca gcaactccaa
    24421 caatagtgaa gaacatattt attagaactg taacaaaaat accaaatttt gaagctaaaa
    24481 acatacaaag aggaatctgc cacataaata gtaaaataat taatatagtt gcaatgatat
    24541 tttgacctat tgaaatagtt tctttataga ttatcccaac aaaaactaca cctattgcag
    24601 aaataattga tgctataaaa cagcaaataa tacagtaaat catttttcca gtccaaacat
    24661 ctttcatttc aattggcaat ggtaaaatac cacgatattt acttttttca tcttttaata
    24721 ctattaaaga acatattaat gttaatgctc ctggaagaaa tgtcgtatac caccagttga
    24781 aagcagcatt ttgccctcca cctagtccac acaaaagtat acaaaacact ggaactatcc
    24841 atatcaactt cattccaaaa gttcctttca tcttttgaaa ttccactcta ataaatcttt
    24901 ccatattact gccctctctt tctattttca gctacaactt tcataaaaag ttcttctaag
    24961 ttttgttctt ttgatacttc tccttgataa cccattactc cattagaaat tattcctatt
    25021 tcatctacaa cttgttcaac ttcagacaag atatggcttg ataaaataac tgtaattcct
    25081 tgttttggaa aagaacgaat caattctcta agttcttcaa taccaatagg gtcaagacca
    25141 tttgtaggct catctaagat taaaagtttt gggtgattta ataatgcaat agcaatacca
    25201 aggcgttgct tcatgcctag agagaattga cctgaacgct ttttaaaggt atctcttaaa
    25261 tctacagtct ctaaaacttc ttcaatgcga gagtcaggaa gaccaagtaa agtagtatgg
    25321 acttttaaat tttctcgtgc tgttaaattc tcatatatag caggagactc aataagagaa
    25381 ccaatatttg ataaatcctt tctagtccat ctatgtccct caaacattat ttttcctgaa
    25441 gttggattta aaatcccagt tatcattttt aataaagtag atttcccagc tccatttggt
    25501 cctaataatc catatataga attagattta attgctagtg aaatgttatc aactgccatc
    25561 tgctccttaa attttttaga aactcctttt acctgcaaaa tataattact cataattttc
    25621 atcctttctt ttgtcaaact tatttacaag aatcattcta aatcataaat ataaggattt
    25681 tataagaatt aaaaaacaaa aaaagatgtg ttaaaaacac atcttttttt atcttaattc
    25741 tattaatttt ccattgtagt atatctctac ttcttcaatc caaatgctat tatcttcttc
    25801 ttggatgaca tttttaataa tattatttat agtatatatt atattttgtt cattcaaata
    25861 atcatctttc caagaaactc tacttttttt atctggttct atcaagttta ttttaacaag
    25921 attatctttt tccttaactt ctacttccat gtctaaacca ttaaaatact catttgataa
    25981 tgtatctaag attaatcgca gtttatcctt aagtgaactt tcttcatcaa tctgtaagta
    26041 ctttactatt ttctcatcct ttgaaattat ctctataggt attttagtag tttttttaga
    26101 attaatcatt ttactagttg tttcttcttt tgcatcttca tccttcttta caactgctga
    26161 ttctttagaa tcaactagct caactgcact gatgctataa tccatacatg ccgtactcaa
    26221 taaagtagta gcaattatta aaaaacttac tgctatttta ttcataagta tccctctcct
    26281 aattctcttt cgatacttat tataccatag tatagattat atttttatac ttttaaatca
    26341 atttatgaat tattatagta aattatttac aattctaagc tatttgaatt tatttttata
    26401 gtatattctt tctctaaatt cgacagattt ttattcaaaa gcccttttat ttccctcgta
    26461 tttctatact tgttgctatg ttcttcatta tgttcataat catatgaatc attgtcatat
    26521 tcttcatcat tattaaattc ttcaattgct tcttttgact ttatatcaca attaaattta
    26581 tacttattta ctggtatatc aagtcttacc ttagaatttg gaacttctat gtccaggaac
    26641 ttagcaattg gcatatcaga gtacaagtaa aattcacttt cataatttga atttctacct
    26701 attttctctt ttatatttac attttcaggt atatactctt ctatattatt gataaataca
    26761 tctccattct ctgaagatat atccaatgac tctgattcta tgtttacatt tttaacgcct
    26821 aaaattgact ttgttgatag atgaagattg ctattagata ttaagtttaa gttttctaat
    26881 ctatttactt tattttctgt tatagctctg ctaaaacctc cagaagaagt tttatatgtt
    26941 atattatttg aatctacatc atcagatata aataagtacg aacttatact tgatgcattt
    27001 atatctacat tatttggtac atatattcta atttctctat aatcacgtga aaacatacta
    27061 tttatagatg tatttaataa gtggtcgaaa cttctaatct ttttaatttt attttcagat
    27121 tttctttcgc cttttacaac taaagtctta tcttgtaggg ttacactgta tttgtaaaat
    27181 tcattattcc ctcttgttgt cacacgcaca tcttcatttg aactttttct tatcataaca
    27241 tttatattgt caacagctat atctaacttg tcaatattta ctttttcttg ataaagtttg
    27301 ttttctttgt ttaattcagc ttccttttct aaaccaaagt ttattaggct tggcataact
    27361 aaaatccctg accatgttgt ccctattata cctattacca ataaaaccgc agcaaatata
    27421 gcaagttttt tattcatgtt tatcttctcc tttcttattt tctatatctt caaggtcctt
    27481 atatatcgcc tcaaaattta tactatcatc attatattca tcagtttctt ttatgctttc
    27541 ttcttctcta ttatagtaat cattattata tgaatcttca ttaatgtctt tattcaaatc
    27601 ttcatcattt aaagtagctt tttttctttt ttccatcttt tcatttgcct ttatataaat
    27661 attttttctc tttatccaat gtatataatt atttagtaat tgtttaccta gttttatggc
    27721 aaataataaa atttgccatg caagtatctc aagccctaca aatgctatgg ttgcgaaaat
    27781 acaaaacatc ataacatctg gaaccattgc tataaattta atcacaaatg gaattaatat
    27841 aacaaaagca attaatgagc atactaatgc aatagtagca gatacaatag cacatacaaa
    27901 cgcaaatgct ggaacaatta gaaataaaga taacactact aataacccct ttataacttg
    27961 tctggataat cctcctacac cttcttctat acttggtgta agtttatcat ttatattttc
    28021 ttttgattta ttgtactttt ccttagcttc atctttcaag atagagtaat ccttttttac
    28081 atttgattta aatctactaa atttaccatt taatatgtct gtattcatta tttttccatc
    28141 tatattttct tttgatttac tatacttttc ttttgcttca tcttttaaga tagagtaacc
    28201 ttttttcata tctgatttaa atttactaaa cttatcattc aaaacatctg tatttattat
    28261 tttttcctct tcaatatttt tttctttagt ttgtaagata agttcttttg ctatagattt
    28321 tggtgagcca agtgatgcta ttatctccat atcactcttt ccctctataa gaccatctac
    28381 gaaatactct tcataatctc tcaatatatc attaacttcg ctctcagaaa aatctttttt
    28441 tagataatcc tttaaaattt caagaaactc agttttattc aagttcatta cctccctcat
    28501 cttcacttat taaaatctca acagccttta caaattctct ccactcttcc atcagattgg
    28561 ataaattctc ttttcctagt gaagttattc tatagtattt tctagcagga ccttcattag
    28621 attctagtat atatgtttcg aaatacaaat cttttgtaag tcttcttaga ataggatata
    28681 ttgttccttc atttacatct attactttag agatgttatg tactatctca tatccataca
    28741 tatctttctt agatatgaga gcaagtacac aaatttctaa aacacccttt ctaaattgtg
    28801 tgttcatata ctccatcctt tctttaaata cacagtattg tgttttacaa ggtactatgt
    28861 taaaacttct tatatcctca taataacaca gtactatgtt ctgcacaata gttattttta
    28921 aatattcttg ttgattaaat ccttctataa atgtataata ctctaatcag atatatttta
    28981 tgaaagtggt gataaattgg ctaaaatgaa agatgataaa acaatattaa tcctaactgc
    29041 tcaatttggt gctggacata taagtgctgc aaaagcagtc aaagaatgta ttattgaaaa
    29101 atatagtaac tataatgttg ttatacaaaa ctttataaat gcaagtattc ccatgatgaa
    29161 taagcctatg gtaaaacttt atgaaaacaa tacaaaatat actcctggat tatataatta
    29221 ctattattac tttaagaaat cgtttgattc aagacatgat ttatctcata aattatatac
    29281 acctaaactt tctgagtata ttgctgatat aaatccagat ttaattatct ctacatttcc
    29341 actagctgct gcttgtgtaa ataactttaa gataaaaaat cctgatataa atatacctac
    29401 acttacagtt ataacagatg ttgtagatag tatggaatgg gtttttgaaa atacagattt
    29461 gtattttgtt ccttctcctg aaataaaaaa tagatttttt cagaaaggaa taaatcctga
    29521 ctccataaag gttactggag ttcctgttga taagagattt caaattgaaa gtaaagaact
    29581 atgttgtgat aaatatagac tattacttct aggtggagga agaggtctat ttgatataga
    29641 tgaggatttt atgcattgga tagatgaatt tattgaagaa catagtaatt ctatagaaat
    29701 tacaatagtt actggtaaaa acaaaaaatt atatgacaat ctaactcata aaaaacctct
    29761 aaaaaatatt aaagtacttg gatttgtaaa cgacatgtat aatctaataa gagaatgtga
    29821 cctaatgcta actaagcctg gaggagcaac tatatttgaa gctattcaat cacaaactcc
    29881 agtactcgta aaaatgccaa aagttggaca agaaattgaa aacgctaaat ttataataga
    29941 taagggtctt ggcatgattt atagtgatga cctagacctt aaaaacatat tttataaatt
    30001 agtatcaaat gaatttgatt ctataataaa ctttatgaaa aaaaatttaa aagaatttaa
    30061 aacagttatt catccagaga aaattgctga ttatatatca gaattaatag ataatcatta
    30121 cagttaaatt gtactattaa aaaatttcaa acataaaatt aaaggcaatc aagtatgctc
    30181 ttacacttga gaatttactc atagtgttta ataatacttg attgccttta tcatatcaaa
    30241 atcaaattgt tatattagta tatatttttc ttgtactgca tatacagttg ttgtatttct
    30301 tccatacttc tctttaattc tatttgtaaa tctgaagcag tctggtaatc cttattttct
    30361 atagcttctc tcactctagt gaatagtgat tctctagtta aagtatcctt cataatattg
    30421 aactttaaat ccgatattga gttccaaact acctcatcaa gcgcatccat attttctttt
    30481 gtgtgtatct tgacaatact tcttattttt tgaatcccag cctctattat tctagttttt
    30541 aatttctttt gccacttatc tatagctcca atcttaaatg attctattat actatcagta
    30601 aatacatcac cttgttttaa agattttaat tttgaagcat atatttctaa gtttttcata
    30661 ttttcataaa ctgtagctgg tggtattcca aatcttgcat ttctttcttc caaactataa
    30721 tgttcaaata catcattttc atctctatat gctctatctt tttctaaata gaaactttct
    30781 tcacctacat ttttagataa ctctttttca agttcttttg tactaagacc actcttagct
    30841 gctgctttta taccatccaa cattgtttga taacatcctg ctattactaa atacgtgtta
    30901 gatagagggc ttggtgatct taactcaaat cttacagtct ttggattttt catatctctt
    30961 attaatccaa caagcactga cctatttctt gatggaatct cataactatg ccctaaagat
    31021 gtaactatgc atacaggagc ttcaaatcca ggaactaatc tattaaagcc atcattagaa
    31081 gctgttacaa ttgggtttaa tacttcataa ttgtaaagaa gtcccataag agccccatat
    31141 cctagttcac ttagataatc ttcttttaaa tcttttggag caaatagatt ttttatactt
    31201 ccatccttta acttcgcact tactcctaca tgtgtatgtc caccacttcc tgctactcca
    31261 tgaattggtt ttgctttaaa tgtaacttct agtccatgtg atgtaaatac atcctctata
    31321 acatctctta ctaataattc attgtctgct gcttgtaatg gtgtagaaaa cttccaagaa
    31381 acctctaatt gctccatagc atggtttgtt cttccatcta tactaataga actttgtatt
    31441 cctccgacct ctttgtgagc catttcaggg tttacaccta gcttttgaag tataattaaa
    31501 cttttctcta aacaagttct tataatacca tgagttcttt tccagtattg ctcttttagg
    31561 ctttgtgata catataattt ctctaagtca gctttatcct caggagtatt aacccagaac
    31621 tcaagttctg tagctgctgt taacattatt tcctctatat catctactga atctattcct
    31681 atgttattta ttacatgtgg atattctcta aatatttcat acattgactt tttaaagtac
    31741 ttatctgctt tttgaagtac tcctctagag catacttttt tattatcatg tattaaaaat
    31801 gcaggtatct ttaatgttcc aacaggtaga cctacttctt cgtctatata ttccatattg
    31861 taatctacat accaatgaca acttttatct ggcattaaat ctactttcgc attatttaat
    31921 gtagctatat tataaagctc aacacttgaa ccatcagtct gtatagctga ttccaaaaat
    31981 ttatctatat cctccaaaaa taattctaca ggaatctttt catctgttgc atttcctcct
    32041 aaatcaaccc ccattaagga aacaaatctt atatttttat tgctttttag gatttctctt
    32101 aattcttcat tagtgtgttt atctttctct attacgtata atagactatc catttttcca
    32161 ctctcccata atttttatgt atattttatt ttgttaaata caagataaat ttcattttcc
    32221 ttacatttat gaatttttct tgcaaattat tcgtgtttta ttcgtgtttt tatttatatt
    32281 attatatatc aagtataaaa agttcgcaat attttttatt ggaaaaaata ttatacatac
    32341 aatagtttaa catttttaca aatatggggt atactaaaat aaaagtattt ttatttgaaa
    32401 atttaatttt atttataata taatctatag taaaagaaat aataaaaaaa tttaggagat
    32461 aaactttatg gaatacataa ttttcgattt ggaatttaac caaggatttg ataaaaaact
    32521 caataaaact gtatccaatg aaaagtgtcc ttttgaaatt atacaaatag gagcaattaa
    32581 attggattct aaattcaata taatagatac gtttaatagc tatgtaaaac ctacaattta
    32641 taaagacata catcccttta ttagtcgtat gactaatatt aaaaattctg attttaatga
    32701 ttcgcctact ttccctgagg tctacaacaa ttttataaaa tttatatcat cacaagaccc
    32761 tatattatgt gtttggggag ctggagattt aaaggaatta tacaggaata tcaactatca
    32821 caagctacca tcaaattcct tacctaaatc ttatattaat atacaacaac atgcatctaa
    32881 atatttcaat aatccagcag gaaaaagcat tggcctacaa aatgctattt ctatattaga
    32941 acttgatgaa aaaatgtctt atcacaatgc tttaaatgat gcatattata ctgctaaagt
    33001 ttttattaag atatacaatc caagtatagt cccagatata tatctttata cgagtataaa
    33061 acctaaaact ataagatatt ctaacaaaaa aagagttgat tatgataagt tatttgatga
    33121 atttaggaaa attttaaatc gtgaattaac taaagacgag aaaaaaatca ttaacttagc
    33181 ttataatatg gggaaaacaa atcaatttac attagaaaat gttaagcaaa gaaaaaacaa
    33241 atagagttta tttagataaa aaataggcat gtagattaaa aaactagtta actttaaatt
    33301 tatatctaca gcccaatttt tatcataatt aatttttatt ttatctctaa ttcaactgga
    33361 caatggtctg aacctaatat ttcagtgtgt atatccgcac ttactaatct atcttctaat
    33421 tttttggatg cacaaaaata atctattctc caccctgcat tattttttct tgcattaaat
    33481 ctatatgacc accaactata aacaccttct ttatcaggat taaaatatct atatgtgtct
    33541 ataaacccac tgtctaataa tttagaaaac ttctctcttt cttctttagt aaaacctgca
    33601 tttttcatat tatttttagg attttttaaa tctatttctt tatgtgcaac gttcatatct
    33661 ccacacacaa ttacaggctt atgattatct agtttggtta aataatctat aaagtcgtct
    33721 tcccatctag ttctatattc tagtctcttt aattcagatt gagaatttgg cgtatatact
    33781 gtaacaaagt aaaaatcttc aaactctaga gttatcactc taccctcttt gtcatgttct
    33841 tctatattta ttccatacat tacttttaaa ggctcttttt ttgtaaatat agcagtacct
    33901 gaataaccct ttctctcagc ataattccaa tattgaaaat atcctggtaa atctaactct
    33961 atttgccctt cttgcaattt agtttcttgt aaacaaaata tatctgcatc tacttctttg
    34021 aaaaagtcta aaaatccttt cccaacacaa gctcttattc cattaacatt ccatgatata
    34081 aatttcatac ttatactcct catctaaaca ttgacacact ccccatagct aaagatgggg
    34141 gcttttcaac aattttattg taaattctta attcactttt attttaacaa tgctatacta
    34201 taatttcatc taaaattact atttacttaa tacctaaaaa tatatgtttt aatcaatttt
    34261 taactttttt gttaaatctt cagggctcat tgaagaaaca tacatatttg ttccaagttc
    34321 aaatcctcca aaattatatt ttcttgggat tatgtgcata tgaacattaa aatacgattt
    34381 tgtttcaatc tttgttggat gagtgtgaat acataagtta aatggcatat atccattgat
    34441 attgtataac ttcttaaaca acttttcaaa tattgtagaa agctcctgta tattattatc
    34501 atttaactca ccaaactcta ttttatcttt aaatattatt cttacttctc cactatactt
    34561 ggttgcatat ggtataagta ccaaaaaagc ttctccatta taaacaactc ttctatctaa
    34621 acttatttca ttttctatta aatcatcata caaagagctt ttattgctgt cataatactc
    34681 ctttgaaacc aacagttcat tcgtaatttc aggtggaata aaagacatag acaatatttg
    34741 agcatgtgga tgcatcaaag atgctcctgc ctttctcaag aagtttttga agatactaac
    34801 atactctact ttatcatctt tcgacaaatc tctaaatcta tttctataca taaaaaaaac
    34861 atcttcaaat tctttttgac tcatgttata aaaactacga ttatgtttat cgctctctat
    34921 cattacttca tgaacaccat atacatctct tgccatatca tcaattatag gaaatttatt
    34981 gtagacagat tttacaagcc atccttcttc actatctatt tcaaataatg catcagttgc
    35041 atgagcttca tttcctttgc aaaatgggca ttcttcatca tattcattag tttcttcatc
    35101 ttcatttggg atatctgctg tatctaaagg tctttttaac ctatctgtag caaatataac
    35161 aacatcattg gtaattggat ctattcttaa ttctttcata attaacacct cttagttaat
    35221 agcctttaat ataattatat gatatttatc gtatctgtta aataaattta taatattttt
    35281 tataattttg catatttatt attatatatt ttgtctatag ctgaaagatt ataactaaaa
    35341 aatcactatc agtacatcag aatattatct tactataaat taatttatga atacataatt
    35401 tagtggcata aacatgggta ttttactata atttgttaaa agtttatttt aaagctatat
    35461 taattttttt tgatgatttt tacccataag tatgttatta ttatcttgta aagatgtctt
    35521 gtattcaaac atacaattta cataatacaa tatacgtatt taaattaaat agggggtatt
    35581 aaaatgaatt attcaaacag agttagtgca atgcaagcct ctccaatcag aaaacttgtt
    35641 ccatttgcac aagcagcaaa agataaagga atcaaagtat atcacttaaa cataggacaa
    35701 ccagacataa aaactcctaa aggatttttt gatgctgtta aaaactttga tagcgaagtc
    35761 ttagaatatg ctacatcaga aggtattcca gaattattag aagcacttca aaattactat
    35821 aaaacttacg atatgaattt tgaaaaagat gaattattag taactaatgg tggtagtgaa
    35881 gctttacttt tcactatgat ggcagtttgt gacccaggag ataatctatt agttccagaa
    35941 ccattctata caaactacaa tggatttggt caatctgtaa acgtagaagt taatgctgtt
    36001 acaacaaagg cagaaaacgg tttccacctt ccatctaaag aagaaatatt gtctaaagta
    36061 gatgataaaa ctaaggctat aattctttct aacccaggaa atccaactgg tgcaatttat
    36121 acaaaagaag aacttaatat cctagctgaa atagctaaag aaaaagattt atggataata
    36181 gcagatgaag tttatagaga atttgtttat gatgggcttg agtatacaag ctgtggtaac
    36241 ttagagggtg tacaggatag agttataata atagacagtg tttctaagag atacagtgct
    36301 tgtggtgcta gaattggttc tatcgcttgc aaaaataaag gtcttatcgc tcaaatactt
    36361 aaattatgtc aaggaagact ttgtgttcct acattagagc aaataggagc tgttgagtta
    36421 tacaaaactc ctgtttctta cttcaaagaa gttaatgaag agtacaaaaa aagaagagat
    36481 gtattataca atgaattaat gaaggttgaa ggtgttatat gtaaaaaacc aactggcgct
    36541 ttctatatag ttgctaaatt accagttgaa aatgcagaag atttcacaat ttggatgtta
    36601 aaagaattta acaaagataa tgaaacagtt atggtttgcc ctgctgaagg attctatgct
    36661 actccaggtt taggacgtga tgaaataaga ttagcttaca tcttaaatga aaaagacctt
    36721 catagagctg ctacattatt aaaagaaggt ttagagcaat atgtagcttt acaaaaataa
    36781 ttttttaaac ttaatttata taaatttaat gatataaaat gtcccctttt cagatattat
    36841 ttgaaaaggg gacatttctt aattaatata ttaattaaga cttagacctg actatttttc
    36901 attttcttta tatagtgttg gccagtaatc tttattcact ttaattaaag catctaaaac
    36961 ttgtcttgcc ttagttagag aaattataaa aaagtacatc aagaaaattt aagatgtact
    37021 ttttagattg tatttagagt tataattata tagttaaatg aataacaaag aattaatctt
    37081 agtaccatta aatacaaaaa tttttatatt ttttctatct aaattcttct ttatttaata
    37141 tatattgaag agtatttatt gcttctaaat atttttttct gtcttcttca gttaatttag
    37201 aaagtttttc tcctaaacca tcacttaatt tatccataaa atcagttgct atcttatctc
    37261 cctcttcagt aatgtcaatt agatattttc ttctatcaac taaatctctt ttccttgtta
    37321 catacttctt atcagttaaa tcatcaacca tactagttaa actgcctttt tctatattta
    37381 acttagagca taaatcagtc atacttatta ctccataatt ttttatgaaa actaatgctc
    37441 ttaattgtgt tttatttaca ttataatctg gtgcaaattt ttttaggtct tctaagtaca
    37501 ggctagaata aatcttagga aatgttttta ctaaaaaact tatggtatct tttactatat
    37561 agttcatata atcacctcgg ttgttttaaa atttattaaa ttatctaaat aactttattt
    37621 cagtttacat taaaaatatt gcaagtacaa tagtttttga tgaatgttta aatttaatta
    37681 gtaatcttat cattttttta tttttattta tattattcct aattaaatat tatttatata
    37741 gctattttat taaattcatg gtatagtaag taaagaagaa ctcttcacag cggtggagag
    37801 aagacgctag cccattaaaa tggctatctt atttataaat aagatagccg tttttaatta
    37861 tattttatct gtacaattct atactcttag gtctacatct acttttccta agtcttcctt
    37921 ataatctttt atagcaggtt ctacaacttc atttacaaat tctacaactt gttctggagc
    37981 tctacctata aagttttttg ggtccattat agatagtatt tcttccttgc tcattttaaa
    38041 tgaatcatca ttcattataa gttcaattaa gttattatcc ttgccttcat gctttactct
    38101 ataggcagct ttcatagaat attctcttat tatttcatgt aattcctgtc tatctccacc
    38161 tctttttaca gcttccataa gtattgtttc tgtagccata aaaggaagtt cttcatttac
    38221 acgtctattt atcatatttt catatactac taaaccatca gttacattta tccctatttc
    38281 aagtatagca tctgctgcca taaatgcttg aggtattgcc aatctcttat tggctgagtc
    38341 atctaatgtt ctctctaacc attgagtggc ttgtaccatt gcagggctta tagattcaga
    38401 gattatatac ttagataaag atgctattct ctcacttctc attggattcc tcttataagc
    38461 cattgctgat gaacctattt gatttttttc aaatggctct tctaattctt ttaaactttg
    38521 taaaagtctt atatcattag tcatcttatg catactttga gctatccctg atagtatgct
    38581 tattacttga taatctaact ttctagtata tgtctgtcca cttactgcat aggaagaatg
    38641 gtatcccatc tttttacaaa ttttcttatc taactctttt actttttcgt ggtctccttc
    38701 aaataagctt aaaaaacttg cttgagtacc agtagtacct ttaactcctc ttaacttcat
    38761 gttgtctatt ctatagttta aatcttccaa atcaagaatt aaatcttgag cccataaaca
    38821 agctcttttt cctactgttg taagttgagc agcttggaag tgtgtaaatc caagagctgg
    38881 catatctttg tacttaagtg caaattcttt taaattgttt attaaattta caagctttac
    38941 tcttagaagt tttaaagctt cattcatttg tataacatct gtattatctc caacatatgc
    39001 agatgttgct cctaaatgta ttattccttt ggctttttca cattgtaaac cataagcttt
    39061 tacgtgagac attacatcat gtcttacttc tttttctatt tttctagctt catcaaaatt
    39121 tatattatct atattagctc ttagctcatc taattgttct tcagttatat tgattcctaa
    39181 ctcatgttca ccttctgcaa gtgcaaccca taaccttctc catgtagaga atttaaattg
    39241 tggagaaaat atataactca tgtccttgct acaatatctg tctgtaagtg ggtttgagta
    39301 agtagtatat ttattatcta tcattatatt agcaccttcc ttaaatcttt tgtcgtgtga
    39361 ttactgtgta cacattagta cataaataat tatatataat tttacgaact ataacaagac
    39421 ttttttattt tttgttcaca tttatatata gtatttttta tttattacta ttttttattt
    39481 atatccaaat tatctttttc aattaagtaa tccactattt cactatcaac aaaatttaat
    39541 acatacttat atctaattgc atagtattta tcactccatc caagctgatt ttttacatca
    39601 ctttcatctg ccccaagcct taaacttatt gctgcaaatg aatgtctaaa atctcttgct
    39661 gaatattgag aaagtccagc taaatctaat gcttttttga ctataagtct gacatttcta
    39721 tctgttatag aattactctt ttgagttgta aaaataaaat catcactagg tattattacc
    39781 tctggaagcc cagaataatt cctgtaatct tctaaaagtt taaaaaagta tggatgtaat
    39841 ttaactactc tttcttttct tcccttacct aaccttacat atgagttatc gttttcatct
    39901 accataaggt ctttccactt taagctaact aattcattta ataaacaccc agtagtaact
    39961 agacagacta ttattactct atctcttata tttaattttg gtaggatacc tataagttta
    40021 tttatttctt gtatacttag aacatcatct tttgttttta ttcttgttac tgtgggtttt
    40081 tctacatatc taaatggatt tatatctatg tatccttctt tttttaagaa gttataaaaa
    40141 ctatgtaaat aactatatat cttttcacaa gttgatttcg catatttagt ctgtatatag
    40201 tctacaaaat ttttacaatc ttctttcgta gcataaatca attctttccc ttttaaaaat
    40261 tctttaaaca gtataacctt tgataaataa tcgtgtttcg tgtttggatt taattttgta
    40321 gaaaaaacat taaaagtttc atactcataa tcatctagta tttttgtact atacataata
    40381 actcctttcc ttttcataaa ataaaatagc tatactttta ctataccata tatttccccc
    40441 tcaaatatac cccttattca atagataact tttaagttta ttttgttata ttatgaaggt
    40501 tttatgaaaa tatcaatctt ccattgtgca ctacacagta ctatggtatt ataagttagt
    40561 aaaaggtggc atttttttat taatctatga ataaaatatg ctactataaa tttgtattgg
    40621 aggtattttg atttggaaac atttagtttg cttgaaattt ttaaggcagt cattttgggc
    40681 atagttcagg gaataacaga atggctacca gtaagtagta cagggcatat gatattagtt
    40741 gatgagttta taaaattgaa tttttcaaat acatttataa gtacattttt agttgtaatt
    40801 caatttggtt caatattagc tgtacttgtt atatttttta gaaaattaaa tccttttgat
    40861 agcgcaaaga atattaagca gaaaaaagaa acagtccgtt tatggcttaa ggttataatt
    40921 gcagttatac catctggagt tattggaata ctgtttgaag atgatataga tagattattc
    40981 tttaattcaa cagtagttgc tattgctctt attgtatatg gtataataat gatagggctt
    41041 gaaaagagaa ataaaaaacc taagtataaa gatttttctc aagttacata taaattagct
    41101 ctttgtatag gattattcca gtgtctagct cttataccag gtacatctag gtctggttct
    41161 actataatag gtgcagtatt acttggtact tctagatatg tagcagcaga gttttcattc
    41221 ttcttagcca tccctacaat gcttggagct agtgcattaa aacttctaaa agctggattt
    41281 ggatttactg gatttgaatg gcttatttta ggtgttggtt ctgtagtagc atttgttgtt
    41341 tcaattgtag ttattaaatt ttttatggac tatatcaaaa aacatgactt caaagtattt
    41401 ggttattata gaatagtctt gggtatagtg gttcttgctt atttctttct attataatgt
    41461 attctaattt aataacaaat gataaggaga aaagttatga gtgttaaaaa agaaatattt
    41521 gattggatta agtcaatagc tatggctatt gtacttgcat ttgtaattct acaatttata
    41581 agaccttcta ttgtaagtgg agaatcaatg tatcctactt tagatgataa agattatctg
    41641 attttaaata ggatatcata caaggttggt aaacctgaaa aaggcgatat tgtagttttt
    41701 aaaaccaatt tagttgatgg agaaacagga aagaaaaaag acttaataaa aagagttata
    41761 gctactgaag gtgacagaat aaaaatatca aattctaaag tgtatgtaaa tggaaaatta
    41821 ttaaatgaac catatataca caataactat acttctggag atatagatac tgttgttcca
    41881 aaaggtaaac tatttgcaat gggagataat agagaaaata gtaatgatag tagattccct
    41941 gatgtaggta tggttgatga aaatgaagtt cttggtaagg ttatggtgag actattacct
    42001 cttgataatc ttgggaaagt agactaaaaa ataagagact gaattggtaa agtttatttt
    42061 acaaatctca gtctcttttt attttcttaa attacaaata tttttttact aaatatcttt
    42121 tgattctgta ataagtctta ttatatcact tgcttcttca ttaaaagttg ttactatact
    42181 taggtagtct gttgctctac tcatagctaa ataaacctta tttaaatctc ctacaaagtc
    42241 atttacttga taatcttgtt caatatcatt tatagtttga ttgtataaca tctctaattc
    42301 acatactatt accgctttat actctaaatt ctttattgca tatatatttg ctattgtagt
    42361 tcctaccttc ttacttatat ttgtcaaatt atcttctgca catatataag gaatttttgc
    42421 ctcttccaat gcttttttta acatatattg aaagtaaatg gtttttccac tttttaattt
    42481 cttcttattg taagggtaaa cgatagcaac ttcagaataa tcaagacctt ttttacttat
    42541 taaatactca atttcccaga ttacagaact tatttggtca tcaaggtcac ttacttttat
    42601 tatatcaaca gacttatttc cacctctaag tgctttagta taaaagaaag tactaaattc
    42661 tgtatttggt cttaattcgt tgatatatga gttagaatta tttgaaaatt tatttgtaaa
    42721 atctacaatc tctttagctt gtctataatt tttacttaag ataatcttat catcaaattc
    42781 tataccatta tataattttt taaatatatt caatctatta gagatattca aggagttaca
    42841 agaacacaca ttaaatatga attttgtttt atataaaaac tcccttataa aatctatttc
    42901 atactctaaa aagctttctg cttcatcaat aaaaatagcc ttgaacatat ttttattttt
    42961 tataatgttc tgtgcttgtt ttacaagatt attaaaggtc ttttcgtaat cattttttaa
    43021 catgttataa tctacaatta aattgaattt tttagctagt ttaaatataa aagaactaaa
    43081 tgtgtgaact tctaaattgt tattatcttt gtataataac tctatcctct ctcgaagctc
    43141 attgcacaat tgttttgtat gtgtaaatat gactaattta tgatgtggat atacttttgc
    43201 taattttata gccctagaaa gcataattgc tgttttacct ataccagaac caccttcaat
    43261 aagtgtattc ccatatttaa tagaaacaac atctttaatt tgaacgtctt ccatcatagt
    43321 tgctgtatac ttatagtcat cattgtagaa tgaaattttt ttaaattttt catttagatg
    43381 aagtttatca tttattatat agtattctga acatatgtct agtaaaaata aatttaagtt
    43441 tatttcatca ttctcatcat taagatattc ctccagcgaa cccttattca ttatatcttg
    43501 aagcttattt ttatctatta tattattatt aacaaattct tcaaattcat atgtttcctc
    43561 aacttcaacg tatggcataa tgtaaacgta gttataactt atatttctat tcttttgtcc
    43621 catttttagt ttcaaaagtt catattcctc attcataact tcaagtaact cttcttctaa
    43681 aataaaaaat atatcttctg ttgtatccat aaattttata aataaaattc ttccatcttt
    43741 aacatacaac aaatcggtat ttattccttt aaaaggagta acttttggca ctactttaac
    43801 gtcctcattg atattttcgt aaaatatttt ctcgaactcc ttcaatttta gggcgtctaa
    43861 ctgagaattt atatttatgt attggctcac ttacattacc tccttctgtt atacttaatt
    43921 ataccatttt gaactatatt tttatatata ctttttatag gcaaatttag taaataaatt
    43981 caaaataaat acaaataaat acaaaactgc taaaataatg ttgcaataaa tatagatatt
    44041 tattgttata gaatactttc tgtaaataat aaaacgataa atttcataat taatttttaa
    44101 aataataagt aaagttttaa aaaaaataaa tcttattgac taaaaataag atttattata
    44161 aaaaatttaa aaacctgcta aaaataatct attttcatta gcaggtttta tttataatct
    44221 tcttatatta atactattat atcctatttt tatattttac tgtagtattt actatttatt
    44281 ttgtagtaaa gtattgattt tacaacttca ttatatcaaa caaacttgga taattatata
    44341 aataatacat atataaagct ttattttatt aatcttttgt aagtagcact tttagcactt
    44401 agattatttt tgcattatat aaaattaaac ttaaacaatt taaaagccac aagatatatt
    44461 atcatatctt gtggcaaatt taaatttcta aaaatatttt cttattattt agatattatt
    44521 tcttttactt cgcatattct atagctcttg tttctcttat tatgctcact tttatttgtc
    44581 caggatattc aagttcatcc tctattttct tagtcatatc tctagccaat agatgtattt
    44641 cttcatcatt tatagcttct ggttttacca ttattcttat ttctctacca gcttgtatag
    44701 caaatgattt ttctacacct tcatatgaat tagctatttc ttctaatttt tcaagtctct
    44761 ttatatatgc ttctaaagtt tctcttctcg caccaggtct agcagctgat attgcatctg
    44821 ctgctgtaac taatacagcc tctactgttt gaggctcgta atctccatga tgagtactca
    44881 tggcatgtat aacttcttta gactctttat aacgtctaag taaatccata cctatttcaa
    44941 catgtgtacc ttccatttca tggtctacag ccttacctat atcatgtaat aaacctgccc
    45001 tcttagccaa tctaatatct gctcctattt cagcagccat tataccagct atatgagcaa
    45061 cttctataga atgtttaagt acattttgtc cataactagt tctatagtta agtctaccta
    45121 ataatcttat taattccgga tgaatcccat gtacactagt ttcaaatgca gcttgttcac
    45181 catattcttt tataatattg tcaacttctt ttctcgcctt ttcaaccatt tcttcaattc
    45241 tagctggatg tattcttcca tctgctatta atttttctag agcaattctt gcaatttctc
    45301 ttcttattgg atcaaatcct gataaaatta cggcttctgg agtgtcatct attataaggt
    45361 ctatacctgt taaggtttct aaagtcctta tatttctacc ttccctacct attattctac
    45421 ctttcatttc atcattaggc aagcttacta ctgttacagt agtttcggct acgtgatctg
    45481 ctgcacattt ttgaattgca tatcctataa tttctcttga tttcttatca gcttcttctt
    45541 tagcttgact ttctatctct tttatcatta tagacatttc acgtcttaca tctctctccg
    45601 cattggttaa gatgatttct ttggccttat cagaagtaat tcctgatata ctttctaatt
    45661 tttctaactg ttgagttttt attacttcaa cttcttcttc tttcttttcc actaccttta
    45721 atttttcact taggtttact tctttagatt ctaaattttg taattttcta tctaagactt
    45781 cttctttttg tactactctt ttttcatact tttgtacttc tgttcttctt tctctgtttt
    45841 ctctttcagc ttctgttctc cacttatgga tctcttcttt agcttctagt aatttttctt
    45901 tttgtactgt ttctgagtcg tggtgtgctt tatctattat ttctttggcc aagttttcag
    45961 cttgtccaat ttttgcttca gatatatttt ttctaacaaa atatccagct ataataccaa
    46021 cagctgcacc tattacaatc attactacac tatctatgac atccacctcc ttcgttaata
    46081 atcccaaaat gtcatcacta tgattaaaaa atattcctaa taattaaaat taaatttaga
    46141 tattttatcc tcacttaatt ttataatttt ttcaacattg tgtcaagcta atagggagcg
    46201 tggcatgtct ttaattacta gttatttttt tgtattttta cttattcttc tacaatttct
    46261 tttgatactg aagtacctga ttcttcatgt tcttcattta aattgtaaaa tgctctaact
    46321 ttctcatcta tttcagtagt taaatctaaa ttatcttcca agaatttttt aacattttct
    46381 cttccttgtc caagtttagt atcattgtaa ctataccatg aacctgattt tttaactata
    46441 tctacatcag cagctatatc taaaaggtct ccaatttttg aaatcccttc tccatacatt
    46501 atatcaaatt cagcttgctt aaatggtggt gctactttgt ttttaacaac tttaactcta
    46561 gttctactac ctataacttt atcaccttgt tttattgtat ctatttttct aacatccaat
    46621 ctaactgatg aatagaattt tagtgcacgt cctccagtag tagtttctgg gtttccaaac
    46681 attattccta ctttctctct taactggttt ataaatatag caacacaatt tgatttttta
    46741 attgaaccag ttaactttct aagtgcttgt gacataagtc tagcttgtaa acctacatga
    46801 gaatcaccca tatctccatc tatttcagcc tttggaacta atgctgctac tgagtctatt
    46861 actattatat ctatcgctcc acttcttatc aatgcctctg ctatctctaa agcctgttca
    46921 cctgtatctg gttgagatat tattaggtta tcaacatcca cacccaaagc ttttgcatat
    46981 actgggtcaa gtgcatgttc tgcatctata aatgcagcta ttcctccatc tttttgagct
    47041 gatgctacac aactaagcgc aacagtagtc ttaccagaag attctggacc atatacttca
    47101 actattctcc ctctaggtag acctcctata ccaatagcta tgtctaaacc aatcgctcct
    47161 gttgatataa catctataga catagatgtt gcttctccca atttcattac tgaaccttta
    47221 ccaaaatctt tttcaatttt acctaaagct tcattcaacg cttttaattt ttcttgatct
    47281 acactcatct ctataccatc ccttcattta tctacaaaca tttgttctct tgttatatat
    47341 taattatata acataaatca aacctagtca atttaaaaac gctactaatg attatatttt
    47401 tattcattac attttattta taaaccatta ttaataatta tatacacaaa agaaaatatt
    47461 cttaaaatga aaagaggtat actataatag tatacccttt tttacatttt taaaatttta
    47521 agttgttatt ttttatttat taatcattag tttttattta ttaaagcata attttttact
    47581 tagaagacat aaaaagctct ttatttttat atagatattc ccatccagaa tataatgtaa
    47641 gtagtgtagc tataagaatg agaatttcac caatatttaa tatcaataca ttttcaaact
    47701 gagcacctaa caataaaaac actatagata ccatttgagt tatcgtttta agttttccac
    47761 tgtttccagc agcaattact tttccatcag cagcagctat agctcttaat atgctaactg
    47821 taagctctct agccactatt ataattacca tccaactact tacaagatgg tcttctatca
    47881 tacatgtaag tgctgaaata accaataact tatctgctaa tgggtccata aattttccaa
    47941 agtcagtgac tagattgtat tttctagcta tttttccatc taaagcatca gtaattgaag
    48001 ctattataaa aataatacaa gctattaaaa atttatttgg tatattgagc aacataatta
    48061 aaacaaatac tggtattaaa aatattctaa acaaagttaa cttgttaggc aagttcatat
    48121 aaaacatctc ccattaaatc gtattccatt gcatcattta tttgaacact tacaaattct
    48181 cctacttcaa gattgtctac actttttaca tacactatac tgtcaatttc ttctgcatca
    48241 ccttgtgttc ttcctgtata tacattatct tctatctgtt cttctattaa cacctcataa
    48301 gtttttccta tctttttgtc attaagttct tcagatattt tttgttgaat catcattaaa
    48361 gtatctcttc tttgtatttt tacttcttca tctatatggt ttggcaatct atctgctggt
    48421 gtatcttctt ctcttgaata tgcaaatgca ccaagtctat caaatttaac ctcttcaaca
    48481 aagtccacaa gttgtttgaa gtcatcttct gtttcaccag gaaaccctac tattattgta
    48541 gttctaagta tagcatctgg tatattactt cttatcagat tgattttatt taatatatct
    48601 tctttagtag tttttctatt cattaatttt aaaatattgt tacttgcatg ctgtattggc
    48661 atatcaaagt aactacatat attatcatat ttctttataa cttgtatcaa ttcttctgtt
    48721 atagattctg gatatgaata cataaccctt atccacttaa atccatctat ttttgcaagt
    48781 tcttctaaaa gttctgataa tctttctttt ccatataaat caaaaccata ctttgtcgta
    48841 tcctgtgcta taaccacaag ttcttttact ccagattcag ctaatttctt agcttcttta
    48901 attatatctt caaattttct acttctatat ttacctctta gttttggtat tatacaataa
    48961 gtacaattat tggaacatcc ttctccaatt tttaaatagg ccatatagct aggtgtagat
    49021 atatatcttg gtaaatcttc attaaataca aactctatat cattaaggct tacaatttga
    49081 tgcatttcac ttaattcttt aagtatttta tctatatttt gatagcttcc tgttcctact
    49141 atagcatcta tttcaggaat ttcagttttt aattcttcag aatatctttg ggctagacac
    49201 cctgttacta tcaacaactt taaattgcca gtttttttta actctgcaaa gtttattatc
    49261 gtatctatag attcttgttt agctgactct ataaacccac atgtatttac tataattaca
    49321 tcagcttctt caaaatctcc aattaattta tagcctttgt tatttaaaat tcccatcatt
    49381 atttctgcat ctactaaatt ttttgagcat cctaatgatt ccaatgctat ttttaacatt
    49441 cactttctcc ttccaatata ctctcatata agtctataac atcttctaaa gctttttgtg
    49501 tatcattaaa atttataatc ttactatact tatatttctc tactgaatgc atataaagtg
    49561 ggtcgtagta ttctaaaaga tatcttttta caagttcttt atattcacct gattctaata
    49621 aatcaatata atcatctact actttattac ccaatctttt tctaaacttg tttatacatt
    49681 cttttaaaat caatatatta ccttcatctt tatcataaat ataatctcta caaagtctat
    49741 caactctatt ttcaatatca cattctaata atatatgatg tccttctcgt gtcattgcct
    49801 caaaaatttc atttggaact gtaacacttc caactcgttt gctttcactc tcgacaaata
    49861 tataattctc tttcgaaaaa aatatacttt caaatagttt tgtttcaaag ttcttttgag
    49921 atggtggctt tttatcaaaa gttataaaac caaaggtaga accactgttt ttagctatgc
    49981 cttctaaatc cagtacgtct attccttttt catctaataa atgtaacaaa tcagtctttc
    50041 ctgtaccagt caatccatga acagatacaa agttttttgt atccattaca tgccttaaat
    50101 actctaaaac aaaatttcta taagccttat atccaccttc aagttgatat acatttacac
    50161 ctaatgatga taataaattt actatactgc cacttctcat tccgcctctt gcacaatata
    50221 tgacaatatt atcataattt aatgcaagtt ctgcagcttg taaatatata tcctttaatt
    50281 tatacgatac atagtcaaac cctttttgta ttgcttcatg ttttccctgc atcttataaa
    50341 ttgttccaac ttcattatgt tcattatttt taaaaagagg catattgatt gcattcaata
    50401 tatggtcttc ttcatattct ccttcagttc tcacatctac aaatattact ttatctagct
    50461 taagtgcttt ttctattttt ataactgaca attctattca ccttctaaat tctgcaaatc
    50521 ctgtttgctt attaatacct ttctcggttt acttccctca cttgctccaa ttattcctct
    50581 ttcttccata gaatctataa gtctagctgc tctattgaat cctattttaa atcttctctg
    50641 tagcatagag gcagatgctt gaccactttc cacgacaaat tctatcgctt cactcaaaaa
    50701 ctcatcctca tcactaccct ttgaagtatt aaccttagat atagtttcaa ttatatcttc
    50761 ttcatatttt attccatctt taacctgact ttttacaaaa tcgattactt tttccgactc
    50821 actctctgat atgaatgccc cttgaagtct aactggtttt gctgcaccaa gtggatagaa
    50881 taacatatca cctttaccta gaagcttctc tgcaccaccc atatcaagga ttgttcttga
    50941 atcagtttga gatgatactg caaatgctat tctagatggt atattagcct ttattacccc
    51001 tgttataacg tcaacagatg gtctttgagt tgctacaatc aagtgcattc cagcagctct
    51061 tgccatttga gctaatctac aaatataatc ttctacatca tttgcacttg ccatcattaa
    51121 atctgctaac tcatctatta ttattactat tttaggaagt ttttcttccg ctttctcatt
    51181 ataacttgtt acatctttta cttgagcatc tgcaaataat ttgtaccttc tattcatctc
    51241 tgtaactgcc caatttaaag catttgcagc ttttttaggg tcagtaacta ctggtatcaa
    51301 tagatgtggt attccattat aatttgcaag ttcaactact tttgggtcta ttaatagtaa
    51361 ttttacttca tcaggatttg ccttatataa aatactactt attaatgtat ttacacaaac
    51421 actctttcct gaacctgtag aaccagctat tagtaagtgt ggcatcttac ctatatctcc
    51481 aattataatt tttcctgcta cgtcttttcc aagtcccatt gcaagaggag agttaaaatt
    51541 attaaattct tcactttcta gaacttctct cacaccaacc atttgagctt cttcatttgg
    51601 aacttctatt ccaattgcac ttttaccagg aattggggct tcaattctta tacttttagc
    51661 tgctaaactt aaagctatat catcagttaa atttacaatt ttacttacct taactcctgg
    51721 acttggttgt atttcatatc ttgttatagt aggtccaact gtaacttgat taatttttgc
    51781 ttccactcca aaatctgata gtgtcttttc taaaagagaa gcatttttca acactttctt
    51841 tttaccattt tcatcagact tcttatttac tttatttaaa agctcaatgc taggcttttt
    51901 atagtttgaa taatcctcat taactggctc tgctacaata ctcataggtt gagttttttc
    51961 tatatttaaa ttaggtttag ctatatcaac ttttttttct ggtttagtat ctacaactgg
    52021 attttcattg gtagcttttt gtaattcttt taaaacatct aactctggca tactttgagt
    52081 tccttctaat atttctaaat actcatcttc tgccttatta aatccaacta tttttatagt
    52141 tttatcatct acaccatcac tattttcttc ttcaaaatat tcatcttcat catcatcatt
    52201 attaagacct tttgacatta accctttaaa gaaacctggt tttttattta tagtagtatc
    52261 atctacttca tcagtcatca tatctattgc agattttttc atatttgcaa ttttatcttt
    52321 aaacgttaaa ttgctgtctt tagatgcttt agattttgat tttgcatttg acaccaaatc
    52381 ttttatagaa atattaaata taaacattac agaaagtata agtgcgaaga tacttattaa
    52441 ccatccacct gctataccaa atattttact catataatac gcaatagttg ttgctatcaa
    52501 accactacct tgtccactta cacccaattt cataacatca tcaaacatgt taccttttag
    52561 tgggctatct acaggaagag ttcctgcatt taataatcca taaaatacaa atataaataa
    52621 aataattatg tagtatagtt tagtctttct tagcctatat atatattcat ttccatcaaa
    52681 aaatcctaaa agtcctgtta taattactat aaatggtatt gctattgaaa gccctccaaa
    52741 tagtccctta aaaagatttt gcattaacac aggtatccat cccatagaat tagaatttaa
    52801 actatataat aaaaatacac ctataaatat tgttattaaa ttatgatatt ctgcattaaa
    52861 acttaaggta tttaccttct tttttttctt ctttttcgtg gccattaata tcactcctta
    52921 tttttagcaa gttttacccc ttcacagcaa aaagtgctaa tgccttaaca ctaacactcc
    52981 tactttatta catcattata tcataaattt tattatttaa acaaatttta atcattattt
    53041 ttttcttcct cagattcttt tataagctct cttaattttt taagtgcttc ttttagtcct
    53101 ccaacttcat ctataagacc ataatccaca gcttcttttc ctattaatac actaccaaca
    53161 tcacttacaa gttcatcttt ttcatgcata agtttttcaa gtacatcttt tttgatattt
    53221 gatgttctta ttataaattg aattattcta tcttgcatct ttttaaaata ctcaaaagtc
    53281 tcatttatac caatcacaag accagtagtt cgcactggat gtataatcat ggttgctgtt
    53341 ggtgctataa atgagtaatc tcctgctgta gcaagaggaa cacctatact atgacttcct
    53401 cctagaacaa gagtaactac ttttttagat gtactgttta aaagttctgc aatagctaaa
    53461 cctgcttcaa tatctcctcc aacagtgttt aaaacaacta acactccttt aacatcattg
    53521 ctttcctcaa ttgagtatag cattggaatt atatgctcgt actttgtagc ttttttttga
    53581 ggatttccta taaaatgtcc ctcaatttct ccaattatag ttatacattg aatatcttta
    53641 ggaggttgag gtggcatttc attggtacca aattgcttta tacattctct ctcttcgcaa
    53701 ctagattctt cactacaatt atctttatca aatttttcat tatcttctct ataatctttc
    53761 ataaaaaaac tcctatcaaa attatattta atttagtttt accaaataaa tcaaatatat
    53821 taagatatat atgaaattct taaatttgat taaaaaataa ttgtattata cagtttattt
    53881 taaataaaat tgttggtgta tagcatgtac tgctgtatgc atatcttctt cactaactaa
    53941 acaagatata gtcatatttg agtctgatgt ttgtaaaagg gatacccctg cttttgataa
    54001 tcctctaact acctttgaca tgataccaga catttcatca gcaattcttg aacatatcaa
    54061 tgttacctta gcacagtctc tatttacttc ataatctaat tcaaatttat ctagtatttc
    54121 ctttaatgat tttatatcag catcttctac aacaaatgct ttttctgata taaagaaatt
    54181 tatcatatct atagttataa gtttcttttc tatctcattt aatacttctg taaacacttc
    54241 ttctgctgac ttaatcttaa cttgtgctac gctatcttta tttgcaacag caaccttaaa
    54301 atctctttct tgttcatatt ctatattgtc ttctaagtgt ctacataaag aacctatttt
    54361 tgtaccttca aaagttggat tcattgtatt ctttatggct aaagttatat ttccactttt
    54421 agccaactgt actgctcttg gatgtattac ttttgcacct ttgtcagcca tttggaatac
    54481 ttcctcatag tctataaaac tcaatacttt agcgtttggt tctactctag ggtctgcagt
    54541 cattatacca tccacatcag tgtaaatttc aactgtttca cattctaaag ctttaccaat
    54601 agcaactgct gatgtatcgc ttcctcctct tccaagagta gttatttctc catcatctgt
    54661 tacaccctgg aacccagcta taactacaac cttaccatca tctaaagctc tttttacctt
    54721 tttaggattt atatacttta tctttgcatt agaatattca tcacttgtaa ttatacctgc
    54781 ttgctgacca gtaaagaaaa cagaatctat cccctgtgca ttcaataaat tagcaagaat
    54841 tgttcctgat attatttctc cacaagacat tattaaatca agttctcttt tacttggctc
    54901 atcatttact gcactacaca aatttataag tgtatctgta gcatatggag ctccttttct
    54961 tcccattgct gaaactacta atactaattg taattcttca tcattttttt tgtatgcttt
    55021 tactatctta catacttcat tcattttttc atatgattct actgatgtcc caccaaactt
    55081 ttgcactaaa atactcattt tttcctccta aatatatccc tcatattcta taattatcat
    55141 gtcattacct atttttttta catttctcca tggtacttct aaaaatgact tatcttttct
    55201 tctggcaaaa aatccttttt cttttggaat tagaagcgct aatataccgc ctgtagtttc
    55261 atctagtata aggtcacatt ctccaatgac ccccaatctt tctcctgtga ccaagttaac
    55321 tatttcctta cctgctattt cagataaatt catattttat acctccagag atttactttt
    55381 ttcaatatta atccaagtgt agaatctttt ctacatctct tccaactata catgtaccaa
    55441 tattttcgat attgaatacc ttatcaacaa ccttctttat taaattaata ttaacattat
    55501 ttatacattc aagtatttca tctgtagttt ttactttttt actaagtaac atagatttac
    55561 cagtagacat cattctactg ctagtacttt ctaaatccaa tatataattt ccttttaact
    55621 gttccttgct ttcagatatt tctttttctg taagatagtt ttctcttata ttttcaattt
    55681 ctttctttat taaattatat acatcttgta aattttctgt actcatgctt gcaaatatac
    55741 ctaattcacc acatttccta tataatgtct gtgatgagta tattgaatat actaaacctt
    55801 tttcttccct tattttctga aaaagccttg agcttatact tccaccgaaa atattattta
    55861 ccactgccat tgaatagact tcttcatcat tttcaaaagg aatacctttt aggcacatag
    55921 ctaagttcac ctgttcagta tctttatttt ttgatataaa gcaaggatta aacttagcct
    55981 cacttatgtc tatacttaaa tttttctttt cccagtgtcc aaattttgat ttgattttct
    56041 ccaccatatc atcaaagtta aagtttccag ctatagaaat aacagcgtta tttggaatat
    56101 aatacttatt taagtattct aacatggatt ctctagttat attgtataga gattcttttg
    56161 tcccaattat attcattcct aatccatcat tagcatatat attttccact aataaatcat
    56221 aagataagtc atctggagag tcttcataca tcttaagttc ttccaatatt ataagtcttt
    56281 ccttatctat atcattttta tcaaatttag aatttagtat catatcactc aatacatcaa
    56341 ttcctgtatc tatatgctca tctattagtt ttacataata acatgtacat tctttacttg
    56401 taaatgcatt tatttgacca cccaaattat ctattgaact agcaatctct tttgatgttc
    56461 tgtttttggt tcctttaaac atcatatgct ctataaaatg agaagttcca ctcacctgtg
    56521 cttcttctat cctagagcct gcatttatcc aaatacctaa tgttattgac tttagatatg
    56581 gtatttcttc accaattatt gtaagcccat tttccagtat ttttgtctta tacattacat
    56641 tctcctaaca atttattctt tgtttcatat tggattattg aaaacactat gttttaatta
    56701 tatttatttt ttatatgtat tacattataa gtcagtcttt taattaattc aactacaact
    56761 tatacaatct taaccaaata tttatacttt gtctacttaa atacatcact aagttttcct
    56821 ggttttagtc ctttttctct tacaatagct ataatatcat ctatacattt tgtcgttgcg
    56881 ttggttggat gcattaagat tatactacta tctttaatgt cttttttctt cattctatca
    56941 atgattacct ctggttggtc tttgtatttc caatctatag tatcggcatc ccatttgata
    57001 gaagtatacc ctaatgcttt agcagccttt actgtttctg gaccaaaaga acctgctggt
    57061 gcttgaaaaa atttagtttt ttcacctata atttcttcaa ttatcttttt agaggtctct
    57121 atttgctcat aattgtcttc atatgataag gtagaataat ctaaatgttt atatccatga
    57181 ttacctattt catgtccttg tttttttatc tttaataatt catccttatt cttttctgcc
    57241 cattttccag ttacattaaa tgtaatcttt acattttctt ttttaagtgt ttctaaaatg
    57301 gattctacgt actctgtttc ccatccaagg tctatattac aggttaatgc aacatatcca
    57361 cttttatcct ttgtacctct ttcatatggt aaatctacac cattaaataa attaaatact
    57421 ggcttgttgt taaataactt taataccatt acccctcctg ataatactaa taacactact
    57481 aaaattagta ttatgatttt tttgagctta ctcttattaa gtaccatcat tatcattaaa
    57541 actcccccta attatgtaca aattgtttct tatttaatac tattaaaaat aagctctgtt
    57601 tatgcactaa atataactta agtgattcta tatatatcaa taaagctctc tattaatcag
    57661 cttttaaata gcttctttat aagagtaaag cctgacagaa aaagaactat aagccatcca
    57721 taactatcat tttaaaatta tctacttttt tgtatttaaa aaagcaaaat cctaagactt
    57781 tgcttttaat tatataataa gttatttatt tttatgttct ggttttggta aaagaacttt
    57841 tcttgataaa ttaactcttc ctttttcatc aatctctgta actttaactt caacttcatc
    57901 ccctatattc aatacatctt caactttggc aactctttca tgagctatat gagatatatg
    57961 aagtaatcct tcttttcctg gaagtatctc aacaaatgct ccaaagttca ttattctact
    58021 taccttacct ttataagttt ttcctacttc tggttcaact actatgttat ttataagttc
    58081 ttgagctttc ttaatcatat caatctcaat acctgatata aatacttccc cagtttgttc
    58141 aatatctatc ttaactccag tttcgtctat tatcttagtt attatctttc caccaggtcc
    58201 tattacatct tttatcttgt caggatttat ttgcatttta acaatcttag gtgcatatgg
    58261 tgaaagttct ggttttggct gagatatagt ttttctcatc tctcctagta tatggattct
    58321 accctcttta gcttgtttta aagcacgttg tagaatttct ttatctatac catcaatttt
    58381 tatatccatt tgtattgctg ttataccata ctctgttcca gctactttaa agtccatatc
    58441 gcctaaatgg tcttccatac cttgtatatc tgaaagcact gcaaccttac catcatgctt
    58501 tataagtccc attgctatac ctgcaaccat atcttttata ggtacacctg catcaagtaa
    58561 agataatgtt gagccacata cacttgcttg agatgtagaa ccatttgaac ttaatacttc
    58621 agaaactaat ctaatagcat aaggaaattc ttcttgagat ggtattactg gtaataaagc
    58681 tctttctgct aaagcaccat gtcctatttc tcttcttcct ggtcctcttg atggtctagc
    58741 ttctccaaca ctatatgcag ggaaattata atgatgcata tatctcttgt tttcttcttc
    58801 atctaaccca tctagttttt gaacatctcc taaagcacct aaagtagcaa cattaagtac
    58861 ttgagtttgt cctctagtaa atatggctga accatgagct ctaggtatca tgccagtttc
    58921 acaccatata ggtcttattt cttcaagttt tctattatct ggtcttacat tttcatgtac
    58981 tataagtttt cttacttctt cttttattat atcttgtaat acttcttcta tatctccaac
    59041 aaaatcttca aaagtttctt caaagtgagc taaagtttct tctttaactc tatccatatt
    59101 ttccattctc tctaactttt caaaagtctg aactgctttt ttcatcttat cagttgcaaa
    59161 ttcgcgaacc aattgagtta tttcttctcc tgcatggtat aattcaacag gcattttttc
    59221 ttttccaact tctgcaacta taccttctat aaactcaact atttttttta tttcttggtg
    59281 agcaaataaa atagcatcaa gcattacctc gtctggaact tcatcagctc cggcttcaac
    59341 catcattatt gcttcctttg tacctgaaac aactagatgc attgaacttt tttctctttg
    59401 ctctgcgttt ggatttacaa caaatgcacc atctacaagg ccaacacata ctgaacctgt
    59461 tggtccatta aatggtatgt ctgatataga aagggctatt gaagaaccta tcattgctac
    59521 tatatctggt gtacaatctt ggtctactga tagaactgtt gcaactacct gaacatcatt
    59581 tctaaatcct tttgggaata aaggtcttat tggtctatct atcaatcttg atgtaagtat
    59641 agctttctct gaaggcttgc cttctctctt taaaaaacct ccaggtatct tacctacaga
    59701 gtataatttt tcttcataat ccacacttaa aggaaaaaag tctattccgt ctctaggttt
    59761 ggctgattta gttgtattta ccattaccat actatcactg tatcgaacta tacaactacc
    59821 actagccatt tcacaaatct ttcctatttc tacagaaagt tctcttcctg caaaatccat
    59881 tttaaatatt ttatgttcaa acattaatgc ttgtcctcct cttattaaaa aacacgtata
    59941 tcactctatt tactatatta tcaaaaatac tataaattaa caatataaaa ttatcttcac
    60001 atatatatgc aaaaacctta tattactact aattagaaca acttatagcc aatatatctg
    60061 gccctgtatg agagcaaata gaaactcctc ctcgagtaaa taatactctt cttgctttta
    60121 ttcttttatt tacttcatct tttaatattt cacaatcgtg taaattatct ccacaaccta
    60181 ttgtgacgat ttttccttct aaagaccctt cattcatttc taaaattata tcgaccaatt
    60241 tacttgctat attctttatt cctctaacct tatttaccaa cttagcttcc ccattatcaa
    60301 agaaaaatat aggctttata tttaacatat ttcctatcaa agcagttgca actggaactc
    60361 ttccactctg ctttaaaaaa tcaagtgtat atggtgcaaa aagcaatctt acactactgc
    60421 gagtattttc taattcatct ataatttctt caaatcccag tccttcttca agaagttcac
    60481 atgcctttat aacatattgt ccactaccta gagataaatt tctagtatca aatatatgta
    60541 ttttttcatt ttcatttaca tcatttttag ctatcatagc actttgaaaa gttcctgatg
    60601 cgtttgcagc ccctgtcata cagattatat gataaccttc tgttatgaac ttatcaaaca
    60661 cttctttaaa ctccatatat gtagcttgtg aagttttagg tatttgcttg atttctttta
    60721 cttttttata aaactcttct ttctttatat ctactccttc tatatattcc ctatcattaa
    60781 aaataactgt aagtggaact atctctatat aatctttttc cgatatttca tctggaatat
    60841 cgcacaaact atcgcatact aactttattt tcaaaataat atcctcctta ttccaactaa
    60901 ttatcctgtt ataaaatttc tatatttatc ctgtctttcc ttttaaattg attatgtatt
    60961 tgtatactat tttaatattc ttacccaata ttattcattt tataattttt tataacatat
    61021 aaactacttt tattattaac tattttactt tataatgaat taactataaa aaagcagtta
    61081 tacactatac ctgctttttt ataaagaatg aaattacttt cttaatccta atttagctat
    61141 taatgctcta tatccttcaa gatctttttc ctttaagtaa gctaataagt ttcttcttct
    61201 accaaccatt tttaatagtc ctcttcttga atggtggtct ttcttatgag tttttaaatg
    61261 tccatttaac tcgtttattc tagctgttaa taaagctatt tgtacttctg gagaaccagt
    61321 atccccttca gctcttccat attcttttat tatttctgat ttgtttatca tttagattac
    61381 ctccgtattt ttttagaaac gcctattact aagcattgat tggagtattc aaatgccgag
    61441 taatggttat tttccttaat cattttatca tacattactt gtttttgcaa acatagtttt
    61501 catacacata atttgtatca ttatacaatt gattttttaa gtcatctatt gaattaaact
    61561 ttctttcatc tcttattctt tccaaaaatt caacaattat attttcccca taaatatctc
    61621 tatcaaactc taaaatattt gtttcaatag acaaagtttt tccattaact gttgggttat
    61681 agcctacatt tgtagcacca aaataagtct catctccaat atgtacaata gaagcataaa
    61741 tacctctctt tggaacgagc atattattct taaggtcaat atttgccgtt gggaatccta
    61801 tagttcttcc aaggtgttta gaatgtataa cacaaccttc taacttgtaa tttctaccca
    61861 aatattcctt gacattagcc atatcaccct gggatactaa acttctaata taagtactac
    61921 tcactcttac atcattgatt ttgatgggtt ttattacttc tacctcaaaa ccaaattcat
    61981 gttctaagct ttttaataga ttaacattgc cttcttttgc ccttgcaaat gtaaagtcat
    62041 gtccaattac tatcttttta gcttttaatt tttttactag tatctcatct acgaaatcct
    62101 ttgcaggtat tttagtcata tactcatcaa atggtatgat tacaactata tctattccca
    62161 aatcttctaa taattttatt ttatcatcat tgcttataat attttttgtt gagtttggtc
    62221 taaagtaatt tacaggatga tttgcaaatg taaatacaat actctgtata ttttcttttt
    62281 ttgcatgttc aactgttttt cctataagaa cttgatgtcc tttgtgtaca ccatcaaaat
    62341 ttcctatggt aatgacactt tcttttatgt ttgctatttc ttttatagat tttataatca
    62401 ccataataaa tgttccccgc taaaatataa tttactctta acttattcac aaactattat
    62461 agcataagta aaagagatag actatagaag ttattatagt actatctctt ttgttgtttt
    62521 tttaaataca ttggttatat gaacatctta tcacttttaa cacttattgt attattgtgt
    62581 tttgataact ttcctaatcc taagaaatta tctgtactgt atactcttac aaattcatca
    62641 tctttatcga aattattttt taaaaacctt ttatcatcta ttgagccacc attactataa
    62701 tattttatag cattagggtt taatacaaca taattaaacg aatcaaggac ataatctata
    62761 tcatataagt atttgtctaa agttttattt tcataaaata attctaattc ttctaatgtt
    62821 attgaattat ctaagtcaaa tttaccagaa gatgttctat tcaaaaacga catatgagct
    62881 ccacaaccta gatattctcc tatatcatgg caaatacttc tcacataagt ccctttagaa
    62941 cactcaacat aaaacattac tttattacct tttatactta gtatttttat gtcttttata
    63001 tttactcttc ttgtttttaa agtaatttca gattgtctac cacttcttac taaatcacac
    63061 attctctttc catttacctt taaagctgaa taaattggag gaagttgatt tatctctcct
    63121 ctttgtgtgt caaaagctct ttctatgtct tcattactaa atttaaaatc atcaactttt
    63181 tttaaaattt cacctgaagc atcataagta tctgtactta tacctaaagt aagctcacat
    63241 atatacgatt tatctttgtt taaaataact tcacatactt ttgtagcttt ccctatacag
    63301 attggtaaaa cacctgaagc atctgggtca agagtacctg tatgaccaac tttttttata
    63361 tttaaaatct ttctcactct acttacaaca tcatgagatg tcatacctgt gggtttcaat
    63421 atacttataa tcttattcat tttactgtca ccttaaattg attttaacac tgcctctagt
    63481 accattttct ttgcattatc aatactatct ctaatagtac atccagcagc ccttacatga
    63541 ccaccaccgc caaataactt ggctatttca cttacatcaa cataattttt tgacctaaaa
    63601 ctcactttaa tttcattttg ttttttctct ttaaataaaa ttccaacttc tatacctttt
    63661 atgtctcttg tatatgttgt tattccatca acatcattaa agctaatatt atttctattc
    63721 atcatgtctt gagttaaaac tatactagat acctttgact gaacctccca tgactaaagt
    63781 cacagggttc ctgcttcaca gaattttgca tattaaaata tgtcttacta attctccaca
    63841 ggctatcccc gtagttccta cggttcttac ataagttatt tattttgaat cgttattagt
    63901 cttaatcctt cttttaatat atttatactt gcatttatat ctctatcgtg agtttcatta
    63961 caactaggac aaatccattc tcttatattt aaatccttaa cttcctcgtt tttataccca
    64021 catttattgc atatttgtga acttgcaaag aatttaccta cctttacaat ttttctacca
    64081 taccaattag ccttgtattc taattgacga ataaattctg accatgatac atctgaaatt
    64141 aagcgagata gtttacgatt tctaatcata ttctttactt gtaaatcttc tatgcaaata
    64201 atatcattct cttttattaa tttagtagat agtttttgta gaaaatcatt tctttgatta
    64261 gctatatgtt cttgaagtcc tgcaactttt aatcttgctt tatttctatt taaactaccg
    64321 attgtttttc tcgataattc tctttgtaat ttagcaagct tgtttaatga cttcttaaga
    64381 tacttaggat tttctataaa gtctccacaa cttgagatac aaaattcttt aattcctaaa
    64441 tctaaaccta tatgattatt agtattttca aatacttcaa tatctacatc agtacagcat
    64501 aatgatacat aatatctacc acttggttct ttagatatag tagcattaag tattctacct
    64561 tgaggtactt gtttatccct tatcttaacc ataccaagtt taggtagttt tatatattga
    64621 ccacaataca taatgtttcc atttgtaaag ttagttttat atgaaaatct attaattttc
    64681 tttgatttaa atttaggaaa tcctgccttt tctttaaaga attttttata tgcattatct
    64741 aaatctttta aggcgttttg tagtgaaaat ttgtcaggtt ccttaagcca ttttaattct
    64801 ttttttaaat tggtcaaatc agaactacac tgtttataag taaaagtttc tttatcgctt
    64861 ttataaacat ctattctttt agcaagatat ttattatata caaatctaca acatccaaaa
    64921 gttttgttaa ttaactcttg ttgtttttta tttggataca ttctaaactt ataggctttt
    64981 ttcactgcta tcacctcacg ttaattgttt tttgatacac tttttaatga ttttat
//
LOCUS       DAFAZV010000022        58969 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFAZV010000022 DAFAZV010000000
VERSION     DAFAZV010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58969
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.022"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            442..2112
                     /locus_tag="KOU88_002000"
     CDS             442..2112
                     /locus_tag="KOU88_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF and EAL domain-containing protein"
                     /protein_id="HBK3211889.1"
                     /translation="MREESNSLSLDHIEIFFELLSQSTEDYIFFWDINRNKFKISSAI
                     FDEFNLSKEIESDLVNCWSKIVYPDDVQIWKDDIQELLHGKKGEHNLEYRLINKYEEI
                     VWISCRGKVYVSDDPKTIFLVGRIKNIGEKNKFDSITGTWNREQFEHRINYLIKEKIY
                     KNGAMFIMDIDNFKNINEKYGHSYGDKVLRAIATEVLEYLPKDVRLYRLDGDEFAFFY
                     PMCTKETIEKIYEKIQMYTNTQHEIESNKYYCTVTAGVAMYPEDGDNYLDLFKHADIA
                     LDIAKISGKNRIKFFSQELYENKLKVISMQQKLRECVENNFNDFELFFQPQVNAVTKE
                     VIGAEVLLRWHSSTYGEVSPVEFIPILEQSNLIIPVGKWIIKEAVKQCKEWHKINPDF
                     KISVNVSYIQLKEDFFRDFIVECLVEYQLRPEFLILELTENCWIPDINLLNDKFISLK
                     GIGVYIAIDDFGTGYSSLNYLKELSVNIIKIERSFVKNITYNSYEYTFLEYIIKLAHI
                     INLKVCVEGIESYEEYDIVKSLGVDIIQGFLFGRPVSASEFYKFQLSK"
     gene            complement(2234..2968)
                     /gene="pflA"
                     /locus_tag="KOU88_002001"
     CDS             complement(2234..2968)
                     /gene="pflA"
                     /locus_tag="KOU88_002001"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBK3211890.1"
                     /translation="MIKGKIHSIETFGTVDGPGIRYILFFQGCPLRCKYCHNRDTWDI
                     KSGKEYTVDEIITDALKYTSFMKFSGGGITASGGESTLQPEFLSELFKKAKENDIHTC
                     LDTSGFVDIETIDPVLDNIDLVLLDLKHMVEEKSIDLTGVGMDKALKLARHLESRNIP
                     VWIRHVLVPGITDDIDNLEKLGQFVATLKNVERFELLPYHSMGIHKWESLGIDYELKD
                     VPDATKEDVQKASEIISKFGVKVYNS"
     gene            complement(3128..5359)
                     /gene="pflB"
                     /locus_tag="KOU88_002002"
     CDS             complement(3128..5359)
                     /gene="pflB"
                     /locus_tag="KOU88_002002"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBK3211891.1"
                     /translation="MNAWQGFKTGRWTKEINVREFIQLNYSPYEGNDSFLAGATENTK
                     KLWDEAMVLFKKERENGGTLDVDTKTVSGIAAYAPGYLDKELETIVGLQTDAPLKRAV
                     MPYGGIKMVENSCEAFGYELDPEIKDIFTKYRKTHNQGVFDVYTPEMRAARKSGIITG
                     LPDAYGRGRIIGDYRRVALYGVDALIEDKNEQKKSLEVSCMDEEVIRLREEITEQISA
                     LNELKKMAESYGFDISKPATNSKEAVQWLYFGYLGAVKDQNGAAMSLGRTSTFLDIYF
                     ERDLKAGIVTEEELQEYMDHFVMKLRMVKFLRTPDYNNLFSGDPTWVTECIGGMGIDG
                     RTLVTKNSFRMLNTLYTLGPSPEPNLTVLWSTKLPQGFKDFCSKVSIDTSSVQYENDD
                     LMRAYWGDDYGIACCVSAMRIGKQMQFFGARVNLAKTLLYAINGGVDEKSGVQVGPRF
                     EPITSEYLDYDEVMSKFEPFTDWLATLYVNTLNVIHYMHDKYSYEALEMALHDRDIFR
                     TMACGMAGLSVCADSLSAIKHAKVKTIRNEQGIAVDFEIEGDYPKYGNNDDRVDSIAV
                     ELVESFMNKIRKNKTYRNSYPTQSILTITSNVVYGKKTGNTPDGRRAGAPFAPGANPM
                     HGRDTNGALASLSSVAKLPYEHAQDGISNTFSIVPAALGKDMTERINNLSAMMDGYFA
                     QNAHHLNVNVFDRATLEDAMEHPEEYPQLTIRVSGYAVNFIKLTKEQQLDVINRTFHG
                     KMA"
     gene            5652..6713
                     /locus_tag="KOU88_002003"
     CDS             5652..6713
                     /locus_tag="KOU88_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBK3211892.1"
                     /translation="MEKRKSIHLHKLNIYLIGGGDRLFITVVLFLVGFLLITKGADIF
                     INCTVEIGKKTNISEIILGATIVSFATTLPEFTVSLLASIDGHTTMSLGNAVGSIICN
                     TGLALGLVVFISPFNVDKKMFFSKSLLLIVSVIVLILLSLDGVITRGDSLLLIIILIF
                     YMVNNYRSVVGKSDTKNRNIKNNTIKDISTKKGKNYRGFSVLEIVKILLLFATGLIMM
                     IIGSQILIESGVIIASFLNIPQGIVSLTIIALGTSLPEIVSSITAIRKNHHEISVGNI
                     LGANILNIVSVIAVSAIPNNIPILSQNRQLDIPFMILLLLTVIIPTLKSNKLSRIQGI
                     LMLFTYFLYISILYFMYII"
     gene            6804..8417
                     /locus_tag="KOU88_002004"
     CDS             6804..8417
                     /locus_tag="KOU88_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK3211893.1"
                     /translation="MNITKFEDLPISEGIKKAIAEMGFEEPSPIQAQSIPAILSGKDV
                     IGQAQTGTGKTAAFSIPILETIDPNNRSLQAVVLCPTRELAIQVSTEIRKLAKYSHGI
                     KTLPIYGGQPIDRQIKSLKSGVQVVIGTPGRTIDHINRKTLKMDNVKMIILDEADEML
                     DMGFREDIEMILSKIPEERQTTFFSATMPRGILELTKRYQKDPEHIKVVRKELTVSNT
                     KQYYIETRSSNKLEVLCRLVDVYDPKLSVVFCNTKRKADELVGDLQARGYFADALHGD
                     LKQTQRDIVMDKFRNGTIDILVATDVAARGIDVDDVECVFNYDLPQDEEYYVHRIGRT
                     GRAGREGMSFTFVFGKEMRKMKDIERYTKSKLIKHNIPTITDVEEKKVGTFFAQVKQT
                     IEEGHLTKQLQWLEGFCNDEDYAMVDIAAALVKLSLGEEMKEEIIEEKPRRERGDRKG
                     GTGAKDGMIRLFINIGRNQRVQAKDIVGAIAGEVGIPGKVVGTIDIYDKYTFVEIPKK
                     DAKTVIEKMKDIKIKGNKINIEKANKKKK"
     gene            8748..10892
                     /locus_tag="KOU88_002005"
     CDS             8748..10892
                     /locus_tag="KOU88_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBK3211894.1"
                     /translation="MDIIKKLSHGCTLDCHDCCKFNVYTKGNNVVKIEGDKNHPYTKG
                     FICKKGMAHLDRLNHKDRIKTPMLKVDGVWKEISFDKAIEIMAEKLTYYKEKYTSKSV
                     MHYDQYGSGSVLKYIGDIFFNFYGGVSRHKGGPCWSAGMHAQKYDFGVAKSHAIEDML
                     NSKSIFVWGKNPAYTTIHTMQIIKKAKEKGIKIVVIDPIYTKTAQIADKYVQVNPGTD
                     GALAIAMAKIIVEDKLYDEEYINSYVIGFEEYKKYLSSLELSFLIDECGVKENDIREL
                     VDLYTNKYSSINVGYGLQKYKNGGNTIRAIDALGAITGQIGFSGGGVNYANKVYPSVI
                     NSDPYNSQSYGEDREFYVSNISKFIEESLKNTSNKVNYASDELDMTSNKVNYVSDELD
                     ITSNKTDYISNELYNLSNKSIKGNIPIKMAVITKSNMLNQLPDLVELERVFSKIEFKV
                     CFDMFITDTATLCDMFIPCTNTLESEDIIYSSMTNPYITYNERAVKPAHKLMDEYYFF
                     MELAKKMGLNDYPFVEKRTYLEKVIEPLKRFDKNLDIEKLKNNYFTIHNPVAWEDKKF
                     ETPSGKYELYSESIKNLGISPTPVYISNKYKEIEDKNISFRLLTNHHADTLFSQHFMD
                     KKSIAQAYINRRMAKKVGIEDKDIVILRSKKAKINVQINIDDGVGNYIVKMYVGWWKK
                     HGNPNSLTDTGISDFGGQVTYNESMVEIIRQN"
     gene            10980..11315
                     /gene="spoIIAA"
                     /locus_tag="KOU88_002006"
     CDS             10980..11315
                     /gene="spoIIAA"
                     /locus_tag="KOU88_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor antagonist"
                     /protein_id="HBK3211895.1"
                     /translation="MVNYSLEHKNLYIEFMCSELDHHVANEIREEIDNLLSVNQVKNV
                     VFNFENINFMDSSGIGVIIGRYKKISNEGGRVSVINISSRVKKIFDLSGLNKIIGIYD
                     TYEEALSSL"
     gene            11329..11757
                     /locus_tag="KOU88_002007"
     CDS             11329..11757
                     /locus_tag="KOU88_002007"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma F factor"
                     /protein_id="HBK3211896.1"
                     /translation="MNNIMEVKFSAISENESLARVIVASFAAKLDPTVDELVDIKTAV
                     SEAVTNAIIHGYEEDSSKFVFLRCEIEGNTIKIIVEDEGYGIENVEKAMEPLYTSKPE
                     LDRSGMGFTVMKSFMDDVEVSSVKDNGTRIEMTKKINVPK"
     gene            11780..12544
                     /gene="sigF"
                     /locus_tag="KOU88_002008"
     CDS             11780..12544
                     /gene="sigF"
                     /locus_tag="KOU88_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigF"
                     /protein_id="HBK3211897.1"
                     /translation="MEVTVAREEKKPLLSHEETLELIEKVQNGDEEAKEILISSNLGL
                     VRSVVSRFLNIGYDREDLFQLGSIGLIKSIYKFDPKFNVKFSTYAVPMILGEIKRYLR
                     DDGMIKVSRSLKQIAIKAKMESEALTKKLGREPSIEELAKAIDVEKEDLVMAMEANFN
                     VEYLQGVIHEEEGSPICLIDKISMKGESEEEKVVDNILLKDILGRLDKRERQIIVLRY
                     FEDMTQSEIGEMLNISQVQVSRIEKKVLSKLKEYIS"
     gene            12824..13261
                     /gene="spoVAC"
                     /locus_tag="KOU88_002009"
     CDS             12824..13261
                     /gene="spoVAC"
                     /locus_tag="KOU88_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AC"
                     /protein_id="HBK3211898.1"
                     /translation="MDKNYKKYVDQISPKPTYLKNYTLAFIVGGIICMIGQAINDLYM
                     KVGGLDKLGASSATSITLIFIGAFLTGLGVYDLIGKRAGAGSIIPITGFANSIVSPAM
                     EYKREGYVLGVGANLFKIAGPVLVYGIGSSILCGIIYYIFKMF"
     gene            13428..14441
                     /gene="spoVAD"
                     /locus_tag="KOU88_002010"
     CDS             13428..14441
                     /gene="spoVAD"
                     /locus_tag="KOU88_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AD"
                     /protein_id="HBK3211899.1"
                     /translation="MKNKRIGKRTVKLENKPTIISTGTIVGPKEGEGPLKDYFDMIMT
                     DDLYGEKTWELAESKMVETASQQAIQKAGKKLSDVNYMLGGDLINQIVPASFAARELA
                     IPFLGIYGACSTMAEGLCIGSMLIDGGFADLVLSGTSSHYCTAERQFRFPLELGNQKP
                     MTAQWTVTGAGSVLLAPNGDGPKVKYVTVGKVIDEGIDDGNNMGPAMAPAAIDTIYSY
                     FEDTNDDPNSFDIIATGDLGTLGKQIAEDFLKEKGVDISKVYTDCGIEMFNLKEQDVH
                     CGGSGCGCSATVFAGYIYDKLRKKEFNKVMLVSTGALLSPTSTLQKQTIPCVAHAVVI
                     VNE"
     gene            14455..14817
                     /gene="spoVAE"
                     /locus_tag="KOU88_002011"
     CDS             14455..14817
                     /gene="spoVAE"
                     /locus_tag="KOU88_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein AE"
                     /protein_id="HBK3211900.1"
                     /translation="MLMDYVRVFIVGGIICLIAQVMMDYFKMQTPYVMVTYVTTGVVL
                     TFLGLYEPLVKFAAAGATVPIIGFGYSLATGVIKSIQSDGFLGIFLGGTTATAGGIAA
                     AIFFGYIMSVVFTPKAKP"
     gene            15000..16016
                     /locus_tag="KOU88_002012"
     CDS             15000..16016
                     /locus_tag="KOU88_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK3211901.1"
                     /translation="MVTIKDIARNLGISYSTVSRCLNNNPNVSEKTKKKVVEEANRLG
                     FHFNVNARNLAKKETNRIGVIFSNNFNHQDTRKFFSDIMDSSINSIETNKYDFIIQPN
                     NNISGDSNVYKMVNGQMVDGLVIVSQSIKKEEYDFLKDNNFPHVFIYFKPSFIGEVDN
                     FFWDDNVYGGYIATKHLIDHGHKDIITVTSDDKSSKMHEDRTKGYLNAMEEANLKTEV
                     IKSKMDFESQVEFLEKYIDKIKKASAIFVQQDVPAISIIQELKTTYGINVPEDISIIG
                     YNNIELISYFRSHLSTIDDPREQVIKNGVDSLVNIINKKSTEHIPRKLYPRLIIRNSV
                     KRIK"
     gene            16391..17233
                     /locus_tag="KOU88_002013"
     CDS             16391..17233
                     /locus_tag="KOU88_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3100 domain-containing protein"
                     /protein_id="HBK3211902.1"
                     /translation="MKEKAGIRNAIIAAFIITILAELIGPISFKVMGINVTLLSILWA
                     IFIGMAVSPHLLGRVIPALKKFIGDNEINVSPYLLSLTLYPLGIMFGINAGPKVGILL
                     QAGPALLLQEFGHMGTMLIALPVGVALGLGRSALGGTFSLCRDTALGIIGDKYGLNSP
                     EGIGTLGTYISGSIFGTLLFSFLAPVGVLLGFHPYALAMASGMGSGSMMGAATASLMN
                     TVPQMSEQILAYSATSGLITAVTGIYIELFLSLPVANYYYSKVAPVIERFRGRKTRRT
                     SNKL"
     gene            17248..17712
                     /locus_tag="KOU88_002014"
     CDS             17248..17712
                     /locus_tag="KOU88_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211903.1"
                     /translation="MEKTFKTIMEQIKIVLFIYIIICFGQMIALKTQAQDLLIGSVSG
                     FLLVIIAIIIKNFVKKPNLPGFAWATLVAFVLSLPISPVGDIIATNVGKINFMSTVTP
                     LLAFAGISVGNQLDILKTLSWKLVVISFIVMTSTYFGSAFISQTVLRLNGML"
     gene            17699..18871
                     /locus_tag="KOU88_002015"
     CDS             17699..18871
                     /locus_tag="KOU88_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK3211904.1"
                     /translation="MECFKEVVNMNELKAKIKEEIKLLSEEKKTSFEKVSDYLFSNPE
                     LAFEEYKSQKALCDLLEENEFNVTKGVGGLETSFEAVYSNGTNGKTVAFLAEYDALPG
                     MGHACGHNIIGTSSVGAGIILKEIMKKHNIEGTVKVFGTPAEERVGGKITMIKEGVFN
                     NVDAALILHPSDASMPDDISFAQVNLKFDFTGKASHAAAFPWEGKSALSGVIALFNSV
                     NSMRLHLKDYARVHGIITDGGSIHNIIPEKSTAIFNVRALSIEYLNEICEMLKNCAKG
                     AAISTGTNVEIVQLDEIYKEIKNDSELVNIVRQNFEVLGEDYVERDLSQGIGSTDTGN
                     LTHEIPAIQAYIKLKENTATHTDEFAVAAGGEEGRVALIKAIKVLAMCGVDILYSK"
     gene            18915..19850
                     /locus_tag="KOU88_002016"
     CDS             18915..19850
                     /locus_tag="KOU88_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1177 domain-containing protein"
                     /protein_id="HBK3211905.1"
                     /translation="MILKQVIEVYDILDKANANGEEVKTYLQGYGEVDVTVKELSSSK
                     GSTDLVKLTIPGKNGKLKGGDAPTLGILGRLGGIGARPEVIGFVSDGDGALVAIAVAA
                     KLLDMQRKGDILDGDVVISTHICPDAPTKEHYPTPFMDSPIDMMTMNENEVDSSCDAI
                     LSIDTTKGNRVINTRGFAISPTVKEGYILKTSDNLLDIMQTVTGKSPFVFPLSIQDIT
                     PYGNNLYHLNSILQPAVATDAPIVGVAITTEMPVAGCATGATNFSDLDSAGRFAIEVA
                     KLFGRNKCDFYDKEEWEMLIKRYGKLNRFQTFGIQ"
     gene            complement(20124..22817)
                     /locus_tag="KOU88_002017"
     CDS             complement(20124..22817)
                     /locus_tag="KOU88_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase domain-containing protein"
                     /protein_id="HBK3211906.1"
                     /translation="MNNDNDKNGNKIRRKKVSSSGNTNKPINRTSANKTRSTKNKKKS
                     KKSDKFKKLRVFGIVFLVLLVVGTAGTAGLVFASLRDVTPVTEAVLDKQTNQTTTIKY
                     ANGKTLSTAPSVNKKTPVPLDKISPYLQHAVIAIEDERFYEHKGVDIKGLFRSVLKTL
                     TGTKQGGSTIPMQVSKMLLTTEQQTIPRKIKDIYYAHEMSKTVSKDKILETYLNNFFV
                     GRGLAGAEAGARGYFDKSAADLTLAESALLAGSTKNPSRFSAYKTSKLEGNETKEDLE
                     NKLLFFVNTTDDDLDDPTQVDFDMIEKIKSWELISNDTYRQLKAGTLVVRKAVSNPEA
                     KKRQEIVLKKMLELKYIKQSEYDEAIKAKIEIKLPQSSDKVSSSVEDLIESEVINALM
                     EQGHTNDEAQNLFYNGGLIVNTTIDPKMQDALEEEFDRNSNFPGHMVGPDGVSQPQAA
                     MVILDYKNGEIRALAGGRNISGRKTLNRATNPHQPGSSIKPLAIYTPAIDTLKITQAT
                     ALSDSRGGYKFEENNKWNPRTTTAGHGSMSLRKALAKSSNTIAVKTAEMLGDSYDECV
                     DIMMDYLKNFGITTLKNNHSGSSEASDRKFPSLTLGGMANGITPLQMAAAYGTLANHG
                     IYVEPSIFTTITTFDGQLLVKNAPEEHKVVDPEVAYVVTDMLESVITEGTGGVATLPK
                     GMPVAGKTGTTNSAYDAWFVGYTPYYVGATYIGDDAGRKDDSGNTIKRREVPHGSTST
                     AKLWEKIMEKIHANLTVTEFEVPKNVYFTKINLEDGGKQSSGSKAAFIEGTAPTKVSS
                     QPSSEDTKKPDNNQPEENNNNNNNTGDNGGGSTPPDNGGNNGGGSTTPPDNGGNNGGG
                     STTPPDNGGNNGGGSTTPPDGGGNNGGGSTTPPDGGGTPAT"
     gene            23031..23729
                     /gene="yunB"
                     /locus_tag="KOU88_002018"
     CDS             23031..23729
                     /gene="yunB"
                     /locus_tag="KOU88_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein YunB"
                     /protein_id="HBK3211907.1"
                     /translation="MNRIVDRKTKNEFRKIIAIFLVILFLSVFIGSFIYIDKTLRPTI
                     TVLAETKALELANRSINKAVAEMVEGKINYEDLMDIQLDNNGKITMIQANTIMMNEIA
                     SAIALEIQDELKKDKTASSYIPIGTALGSPILAKYGPKLEVSIEPIGTVSVNFKTEFE
                     SSGINQTRHRIYLEAQTQVKVVIPLITSTKQIKAQIPICETIIVGDVPESYVNIPEKN
                     LGNVLPNTGKNTNK"
     gene            complement(23941..24948)
                     /locus_tag="KOU88_002019"
     CDS             complement(23941..24948)
                     /locus_tag="KOU88_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S55"
                     /protein_id="HBK3211908.1"
                     /translation="MQLKNFHFKNNTLSKKTNLAKSKFTIVLTFLFLLYFFSNNLIYA
                     QNLQKNEPEYLIPIGNVLQIDAELKNIIVRNPGEASPFRLGDAIVKVNNAEVDGYSDF
                     ANTLNALPEEKQVSILLNRGGQLITMKTTKHILEKISFNNLLSGFATLTYINPDTSEF
                     GAVGHPISVGNARKIPIKTGSISTTKHLNIEKSYKGSVGCINAKRENIIGSFTENTDF
                     GIRGQINNFDISKLKKYKVASLDEVKLGKAQIILQDNFNKCKKYNIEIIDIENQKHPE
                     SKSFKIKITDKKLLAQTGGIVQGMSGTPIVQDNKIIGAVSHAIENDPAVGYGVFIKWM
                     L"
     gene            25176..26060
                     /locus_tag="KOU88_002020"
     CDS             25176..26060
                     /locus_tag="KOU88_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3211909.1"
                     /translation="MKKYRLLVTCIIAMGIIIIGTSNPVSNFYKTTNLISSGNITNEK
                     ADKDENSNKNNKDKNEDKSNSKSNKDKSSEDKSSDNKNEIQKNKKLLICIDPGHQGKG
                     DSNLEPVAPGSSSKKARVSSGTEGIATKKPEYVLNLEASLVLKSILESKGYNVIMTRE
                     THDVNISNSERAILANDKKADMVVRIHADSLNNSSKTGASILIPEKDGKYTAPIYEES
                     NKCAEFIKQNMEQSGIQINGIVQRGDLTGFNWSKVPAVLVEMGFMSNYNEDQMMSNPD
                     YQRKMMQCIADGLDAYFK"
     gene            26262..27812
                     /locus_tag="KOU88_002021"
     CDS             26262..27812
                     /locus_tag="KOU88_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK3211910.1"
                     /translation="MLVVENVSHGFGARTILENVSFRLRKGEHIALVGANGEGKSSFL
                     NIITKKLMPDAGNIKWSSRATVGYLDQHTVLSKGKTIREVLREAFKHMFDLEQEMIAM
                     YDKMGEASDDEMSKLLEETAEIQTILENSGFYMIDAKIQEVANGLGLGEIGLDKDVTD
                     LSGGQRTKVLLTKLLLENPTILILDEPTNYLDEEHITWLTKYLQEYENSFVLVSHDIE
                     FINNTCNVIYHMENGELNRYKGNYDEFVRLNDIKKRQEEQAYDKQVEERKRLEDFVAR
                     NKARVATRGMANSRQKQLDKMEILERPKEKIKPTFAFKDARAASKIIFETENLVLGYD
                     EALTKPLNFHLERGKKIALKGMNGIGKSTLLKTLLGIIKPFEGNVKLGDYLEVGYFEQ
                     ESSRENSNTPMDEVWSEFPGLTNFEVRQALAKCGLTNEHITSQMRVLSGGEAAKVRLC
                     KVMLKNINFLVLDEPTNHLDVEAKDELKKAIKEFKGTVLLVCHEPEFYSEIVDDVWNI
                     EDFTTKIV"
     gene            27841..28488
                     /locus_tag="KOU88_002022"
     CDS             27841..28488
                     /locus_tag="KOU88_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBK3211911.1"
                     /translation="MKKFLNVLFSICISIVIIVGVINFTVGFKQLYYFDIDYLNISEL
                     SGLSKDDIKLNYDYLIDYNLNKNVSEFKLPTLKSSPQGKIHFEEVRNIFQNINKLAKL
                     LLVVSLVGIILSVKNKNIKILKTTSITLIIMPLLLTVPILLNFEKSFIIFHKLLFRND
                     YWIFNPDLDPVINILPEEFFFHSGMMILILILLVSIVLFVMYKLCKSLSIKIFQC"
     gene            complement(28630..28890)
                     /locus_tag="KOU88_002023"
     CDS             complement(28630..28890)
                     /locus_tag="KOU88_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich small domain-containing protein"
                     /protein_id="HBK3211912.1"
                     /translation="MGENYKFFNHKDCEFFPCHKTNKPEEFNCLFCYCPLYALGENCG
                     GNFRYTDKGIKDCSSCILPHKKDNYNYIMSKFQDLVKITSKK"
     gene            29107..30390
                     /gene="hflX"
                     /locus_tag="KOU88_002024"
     CDS             29107..30390
                     /gene="hflX"
                     /locus_tag="KOU88_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBK3211913.1"
                     /translation="MKEIQEKALLVGLNLTTIVKKNDDIDTNESMEELKELTKAAGAE
                     VVGSLIQNKHSVDAAYYIGKGKVEEIRAYSDSLDATLVIFNDELSGAQIRNIENVVGR
                     KVIDRTTLILDIFAQRALSKEGKLQVELAQLKYRLPRLYGMGGEMSRTGAGIGTRGPG
                     EQKLEIDKRHILNKAADIRRELKEVKKNRETQRVKRLKSNIPIVALVGYTNAGKSTLL
                     NELIKTHKDYEQEKEVFVKDMLFATLDVTLRKALLPNKKEFLVVDTVGFVSKLPHDLV
                     EAFKATLEEVQYANLILHVIDATNTSYELQKSTTEGVLKELGVNDKKHILVYNKVDKL
                     ELDIYPKSQEDIVYISAKQGINMDKLLNMIEIALMENTYSVSLMLPYERGDIFSRIKD
                     KYNVENFEYGESGITLDADLDEEDFNIYREYILEK"
     gene            30398..31075
                     /locus_tag="KOU88_002025"
     CDS             30398..31075
                     /locus_tag="KOU88_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBK3211914.1"
                     /translation="MDINWENIDNLEDYFITYLLYKESKTVSQISKIRNISSTEASEQ
                     LIQAKLKIKEMQKDDFEASKDILDKFLELDKIKRLDFMDSLDDEKMVYFKRKVFKRIL
                     VEKNAEDLIVLIWATGELKDDRFLKLLHQLTNHRHSDIRRITYSAIRKIESPSSREVL
                     QKGLYDKNAQTRQYCAKALSKLGDENSLKILQQLKDKNKNFEKEYVLRAYDEAIKSLE
                     NAKNLKK"
     gene            31161..31604
                     /locus_tag="KOU88_002026"
     CDS             31161..31604
                     /locus_tag="KOU88_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK3211915.1"
                     /translation="MIVRRCAGGVVFYANKVLIVKNDRGEWTLPKGKILGGGLPYESA
                     VQRVKVETGIDAKMIDVAGDTMYEFFSRSRQQEVCNAIMWYVMEACNTDCVLAPEFQE
                     GGFYKVKDALEMLSHHKEQALVEVSYKKFKELKKLVSEGDDVPAN"
     gene            31909..32553
                     /locus_tag="KOU88_002027"
     CDS             31909..32553
                     /locus_tag="KOU88_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBK3211916.1"
                     /translation="MSNYRTLHEFGTDEITIEKSVFIGYAKPIKSEEEALEFINEIKK
                     KHKDATHNVWAYTVGKNMNIQRYSDDGEPQGTAGIPTLEVIKKEDLRDVAVVVTRYFG
                     GTKLGAGGLVRAYTKGAKLGLEAGKIIYKVMYQEVKVKIDYTQLGKVQNELMNLGYFI
                     KDTVYEDNVEIVVYSRLEDVEKLSEKMIDITSGTGKIVLGEEFYLSEQNGEILI"
     gene            complement(32639..33016)
                     /locus_tag="KOU88_002028"
     CDS             complement(32639..33016)
                     /locus_tag="KOU88_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBK3211917.1"
                     /translation="MLFALIGFFAGIIGGMGMGGGTILIPALVLLAGIDTKIAQSVNL
                     LSSIPMTLIALAIHIKNKNVIFKLVIPIAVFGVLGAVFGSLLANYLSSDILKKIFGIF
                     LLLVGLFEVKKGFCAKSDKKPLN"
     gene            complement(33016..33402)
                     /locus_tag="KOU88_002029"
     CDS             complement(33016..33402)
                     /locus_tag="KOU88_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBK3211918.1"
                     /translation="MKKTDDLKKKYFDFNLKNTIIGVFTGFINGVFGSGGGTLLVPIL
                     NDIVKVEEHKSHATALSIIIFLTTASSVLYVSKGTYDVNLTIKVAVGSILGGIIGAKL
                     LNKVTGKFLRISFGIIMIIAALRMVF"
     gene            33581..34336
                     /gene="nadE"
                     /locus_tag="KOU88_002030"
     CDS             33581..34336
                     /gene="nadE"
                     /locus_tag="KOU88_002030"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) synthase"
                     /protein_id="HBK3211919.1"
                     /translation="MSNIKIQIDKTVEWLINKVNEANAKGLIVGVSGGIDSAVVANLI
                     KKAFPENSMGVIMSIKSNPQDREDALKVIEGCDIEYLDLDLIEPQSAILDMVVGNLKD
                     KHLYREEYLKMTDANLRARVRMSTIYTIANNLGYLVVGTDNAAEIHTGYFTKFGDGGV
                     DILPIANLTKGEVYEWAKELGVHEDLINKAPSAGLWEGQTDEDEMGTTYNMIDAVLEG
                     RLDEVPKRDQEIIERLHRLSEHKRKTPAQPPKF"
     gene            34419..35138
                     /locus_tag="KOU88_002031"
     CDS             34419..35138
                     /locus_tag="KOU88_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK3211920.1"
                     /translation="MGRIGNIINRKGKQDAQRAKIFTKHARAIAVAAKEGGADPEYNA
                     ALKTAIEKAKADNMPNDNIDRAIAKGAGAGAGEDYETIVYEGYGPGGVAVIVETLTDN
                     KNRTAGNVRYYFDKNGGNLGTSGCVSFMFDKKGQILVGLGDGVSEEELMDVALEAGAE
                     DFITEEDGYEIITTPEDFSSVRDELKAKGYEFISADVKMIPQTTTVLTEESHLKMMNK
                     LVDMLEEDDDVQDIYHNWEVE"
     gene            complement(35305..36309)
                     /locus_tag="KOU88_002032"
     CDS             complement(35305..36309)
                     /locus_tag="KOU88_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBK3211921.1"
                     /translation="MATIKDIAKDCGLSSATVSYVLSGKGNERRIPLHTQELILNSAD
                     KLGYKRSTPIKHNNIKIAFYWQDEGFELASTNILQAINHIISLEHLNINIIIRPYKVG
                     HLCDDEYFFANNYYDGIVLTGINADDIEYLVKNKPKIPVVVVNREIPGFSSVSIDNEE
                     TGRIAALHAIQNGKNDIAVVFNPTSFTCMTLRGKSFLKTCKEHGIHLSDSIYYCSNKI
                     DSGYDIAQKMLAKNSLKKVIFCNHDVVALGMMNAFHESGIVIGEDIQIFAASNGPSRL
                     MARSIPPLTVIDLKMEETAERSLRMIIDTVTGRINGIQQQVIYPSIIYRQSSPAQNLL
                     "
     gene            36575..37471
                     /locus_tag="KOU88_002033"
     CDS             36575..37471
                     /locus_tag="KOU88_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="HBK3211922.1"
                     /translation="MSKVNIFEVGPRDGFQNLKEFLETDKKLKIIDGLIASGIKQLEI
                     SSFVSPKAIPQMKDAKEVATYCVEKYPDVKLYALVPNLYGAKVAWECGIRDISYVISL
                     SETHNKKNINRTHEESIDELKKIMNTYPDMNICIGMATVFGCPFEGLPKIEDAIRFAK
                     RLWENGIREINLADTIGIADPKQVRETISALVEALPECRWQVHIHDTRNMGMVNTLVA
                     IESGITTVQSTLGGLGGCPFAPGASGNTATEDLVYMLERMGYDTGVDFVKLLELSKYQ
                     KSFVNGVYSGHHVNIKSDSCNC"
     gene            37609..38871
                     /locus_tag="KOU88_002034"
     CDS             37609..38871
                     /locus_tag="KOU88_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211923.1"
                     /translation="MDIIALLLFLGVIIIAFVRKNNAGILALAIGVIAVRIFGMDDKE
                     LYGAISNSMFTTLVGITLLFAIVNSTGALKLVAEKIVAASGKRVWLIPIAVFIAGFVV
                     AGVGPGAIPALAIIPAMAVPVAITVGYNPVMLALIGECGLMAGRMTPITPEGQIITTV
                     AEGVGIENVMPTILACQTLSTIVFSIVLFIIFKGYKLKKPINVIDSKQIEKFNIKQII
                     SLISIVVMIAFIIIFDMNVGLAAFAVSAVLIFFNIADEGECIKSIPWSTIVMVLGVGA
                     MMTIVDAAGGIDLMSNALSSLMNSKTATPIMSISAGLMSMVSSALAVVYPTMMPMCVD
                     IAKAVGGVDPLALIAAVGVGGSLAGVSPLSTGGALILAAMGSSKKDFNKEEQNKVFVQ
                     LFIMSAVGLLVIAVVSILSFNAITHLMN"
     gene            38947..40140
                     /locus_tag="KOU88_002035"
     CDS             38947..40140
                     /locus_tag="KOU88_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBK3211924.1"
                     /translation="MKKGALSNIKVLDLTRVLAGPYCTMMLADFGADVIKIEMPRKGD
                     DTRGFGPFVNGESLYYANINRNKKGITLNLKSEEGKNIFLEMVKHADVVVENYRPGVM
                     EKLGLGYDELAKVNNQIIYGAVSGFGCYGPYSERPGYDIIAQAMGGLMSITGQEGGEP
                     TRVGNAMGDVLGGMNLTIGILTALNARKIIGKGQRVDVSLVDSVVSSLETGIQRYFDS
                     GQPELMGNRYASAYPYDSFKASDGSFVIGCGNDKLFEKLCKKVLFREDLLIDERFKTN
                     LNRCEHYKALKPEIEKWSVKHTIKEAVDLISEAGVPAAPIYNLDCVTTDEHIAKAREM
                     IVDISHPIIGNMKVNGNPVKLMTTKAKIDMPAPSLGESNEEIYNGWLGFDSDKIKDLK
                     ENGVI"
     gene            40769..41563
                     /locus_tag="KOU88_002036"
     CDS             40769..41563
                     /locus_tag="KOU88_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBK3211925.1"
                     /translation="MESVMENLNNLKVEVKDKVCVITINRPKALNALNSDTLRELSQV
                     IDVVSENEAILGVIITGEGKVFVAGADIRQMQNYKSEEGRKYAGYAQGIFDKIEALEK
                     TVIAAVNGYALGGGCELAMSCDIRIASEKAIFGQPEVNLGVIPCFGGTQRLSRLVGTG
                     IAKELIFTGRQVNAEEAKSIGLINKVVPSDLLLEESMKMMNQIVEKAPIAIRYAKVVI
                     NKGIDMDLKNALELEKDIAGLTFATRDKQEGMNAFIEKRKPVFENK"
     gene            41658..42998
                     /locus_tag="KOU88_002037"
     CDS             41658..42998
                     /locus_tag="KOU88_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBK3211926.1"
                     /translation="MNTGVIISLVGIIIALSLLVVMVMKGINIFIIAIVCSSLVAITG
                     SLNVYDALKVDYMTGFVGFLQANFFIFLTGTLMGKIMEITGGAKSIAKMIVRWIGKDK
                     ALLSIPIACGILAYGGVSVFVVSFAVFPIALEIFKEADLPRRFIPAALTFGCSTFAMV
                     APGAPQIQNIVPASTLGTDIMAGAVNGFISCAVMFIVGSTILYKMVSKEKANGGHFIA
                     HESDIFDEAEATNSKRENGPNGVIALIPLIVSILIINVKVNGKAIVPIEVGVFIGALL
                     VYLLLNKYQDNAKIVGHVGDACKTTVVAICNTCAVVAFGSVVKSAVGFDFIVNAMTNI
                     PGPPIAGAAVGTTVIAGICGSASGGLGIAAPLLGPVFLAKGVSAAALTRTMAISSAAL
                     DSLPHNGYIVTVTNGLCKETHKDAYMPIFWVTVLTPFIGTIVAVLLFTMFPGLP"
     gene            43135..44367
                     /locus_tag="KOU88_002038"
     CDS             43135..44367
                     /locus_tag="KOU88_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA transferase"
                     /protein_id="HBK3211927.1"
                     /translation="MLNKPLEGVKVIDLTYFVAGPGTSKILADWGADVIKVEPSFGDP
                     GRKTGATMTMPIDDYNNPFYSTYNSNKRGLSINLKSETGIEIMDKLLSEANVFVSSYR
                     TGALKRLGLDYESLSKKHPHLIWGQINGFGDFGPAKDNAGFDTVAFWARSGAMLDIAE
                     KDTSPINPPIAFGDATTSCSLSGGICAALYQQAKTGKGQKVMASLFGQAIWNASSLLA
                     STQFSDEYPKTRKNAISPVINSYRCKDGKWIFLSILEHERYFEALCRLFGREDLIKEE
                     KFASSVESKKNATELISILDGEFAKFTQNEMVEKLTAADIAHEKIQHVNDVVTDEQAI
                     ANNYIYEHTSKNGNKTMLASTPVKFGNIEVNMTCDAPLIGEHSDEILRELGYSDSDIE
                     ALIESGIVTMNKEACEIC"
     gene            44407..45549
                     /locus_tag="KOU88_002039"
     CDS             44407..45549
                     /locus_tag="KOU88_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HBK3211928.1"
                     /translation="MDFRLTEAQLMLQRVAKEFAENEIAPIAAETDKTGIFPRELFSK
                     MAKIGFNGIGTPVEYSGSGGADIEKVIVVTEIAKKCAASAAILSIHTIYAQAILKFGT
                     EEQKKKYLPMMAEGGCVGAFALTEPNAGSDAARAATTAIIDEETDEYVLNGTKCFISG
                     GGQAESLIIFALTDPSKGIKGMSAIIVDKGTPGFSIGKIEEKMGIHGSETAELIFDNC
                     RVPKSNLLGKEGKGFNIAMTCLDGARIGVGAQAVGIAEGALEESIKYSKERVQFGKPI
                     SALQGIQWYIADMATMVESAKLLVYYAADLKARGEKHTKEAAMAKYNASRTAREVTNL
                     ALQIHGGYGYMKDYPLERMYRDAKITEIYEGTSEIHKVVISRAVLG"
     gene            45560..46354
                     /locus_tag="KOU88_002040"
     CDS             45560..46354
                     /locus_tag="KOU88_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBK3211929.1"
                     /translation="MNIVVCLKQVPDTNEVKINKETGTLIRDGVPSIINPDDRNALEE
                     ALKMKDELGAVIKVISMGPPQAKSALKEALAMGADEAYLISDRAFGGSDTWATSTIIA
                     AAIEKVGKYDVIFCGRQAIDGDTAQVGPEVAEFLGIPQVTYAKEVKVQDDKLLVTRYT
                     ETGDYLIEAKMPVLLTAIKELNNPRYPSVKGILEAYNNGDAKITVLTLADLDVDTTQI
                     GLKGSPTNVYKSFVPVKDKHNEIIEGINKKEKAEKLIEILFDLKLV"
     gene            46365..47387
                     /locus_tag="KOU88_002041"
     CDS             46365..47387
                     /locus_tag="KOU88_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBK3211930.1"
                     /translation="MMRAKVNQGINLNDYNGVWVIGEQREGKINPVTIELIGEGRKLA
                     DQLGKELAVVIAGYEVEKEVKELLHYSVDKVYYINDPLLKDFTTDGYAISIANLIERK
                     KPEVVLVGATSIGRDIAPRIAGKVGTGLTADCTKLEIDSTDNKLLQTRPAFGGNLMAT
                     IVCPKNRPQMSTVRPGVMAKAVRNESETGILEVVTPELTEKMIRTRLVEILPQEKKSV
                     NLTDARIIVSGGRGLKRAEGFELIKELADKLGAEIGASRAAVDSGWIEHSHQVGQTGT
                     TVRPELYIACGISGAIQHLAGMSDSKYIVAINKDAKAPIFSICDYGIVGDLYEIIPEM
                     IESLNR"
     gene            47486..48862
                     /locus_tag="KOU88_002042"
     CDS             47486..48862
                     /locus_tag="KOU88_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBK3211931.1"
                     /translation="MKEQWYKDIFARVLSMTDDGFIVVNTSGVIIDINDKYCDFLGKE
                     RKDIIGQNIQSIIPNTKMLDVMKNKYCEEGAIHHYSGGNTKEKSVIVSRSYVENDNGE
                     VVAGVAQVKFRLQSFDVAKKLMSEYMELQYYKEQFKDNCGFDKLIGENRDFIELKKTG
                     VKASKTNFPVLLTGETGTGKEVFARAIHNNSSRSDKPMVSINCAAIPEELLESELFGY
                     DEGAFTGAKKGGKKGKFLVANNGTIFLDEIGDMPLTMQAKLLRVLQESEIEPVGGLKT
                     IKIDVRVISATRKNLSKMVEEGLFREDLYYRLNVINIHMMELKDRQDDILLLANYILN
                     KLNVEYKELKVLSDKVKNCFINYTWPGNIRELQNVIKSAYAVSDDMVIMMCDLPSKMD
                     NISRVAQCNVDSNCSIHEMVENYEKSLIIDVLRKYNWKCSKAAEVMGIHKSLLYKKIK
                     KYEIELNN"
     gene            complement(49194..49538)
                     /locus_tag="KOU88_002043"
     CDS             complement(49194..49538)
                     /locus_tag="KOU88_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211932.1"
                     /translation="MDQIKRLHELQQKSYLTKEEFEELKNNTYIERFELRDECDNSYI
                     YTFYTNDKCNDIKFIKSQFIVTLIKIGFLCECGGVFRQKKIVDEYDYGYNAIYKCDSC
                     GKELDKEVENYD"
     gene            50026..51036
                     /locus_tag="KOU88_002044"
     CDS             50026..51036
                     /locus_tag="KOU88_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBK3211933.1"
                     /translation="MHEDKNDIFESIDTEDFDNKTEEECLELVRKNGLNLIYIKNQTE
                     EICLEAVRQNCNAIKCVQNQTEKICIEAVKQDWRMLEFVEEPTEEICMLAINQDGTAL
                     KYIENQTEELCLRAIEKNGAALEYVKEQTEEICIEAVRNSEFGLARVKNQTEKICMEA
                     VKHCSYNLKWVENQTEEICMEAVRQNGLDLKFVKNQTETICLRAVRQNGMALEFVKEQ
                     TVGICLKAVRQYGMALKFVKEQTEEICTEAIKQDKRALSFVKGDKEKYKALYDNNEPF
                     AKRYVRNVIEKENRALIKKGEENAKIKIAGKLYDRGMSFEDISDIVEIEISKLKVSLG
                     VF"
     gene            51172..51660
                     /locus_tag="KOU88_002045"
     CDS             51172..51660
                     /locus_tag="KOU88_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3211934.1"
                     /translation="MKITVLYQTRSGNTERVAKLIEDGAKKVDGVDVKLMRLDNIDLD
                     YLNESKAVIFGTPTYLANTTWEVKKWFDEDSKKVNLAGKLGAVFATCDYICGGPDVAI
                     LTIVGHLMVKGMLVYSGGGSLGKPFIHLGHVHSIEGPELQDEKAIIFGERIATKAKEL
                     FA"
     gene            51836..53764
                     /locus_tag="KOU88_002046"
     CDS             51836..53764
                     /locus_tag="KOU88_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3211935.1"
                     /translation="MVWHIEYEIFSAIIVIFLMVYFFRSKFIPTLQNKIYCALLIFSF
                     LFIISNILGSFCLNNIDKIPIFITFLLNQIYLLLLPIPAALVSFYVMAIIYQDIRYMK
                     KRLLFLSIPLIICIILSITNPFTHILFGLSKETGYIRGCGYVATFASFFFYAIYSAFL
                     SFKYRKAMHESKIWAIRGFLIVSIVAIILQAIFLQYLLTGTACACSLLLTYLSMQNRG
                     LIIDDLTGVLNRQSFIQELDLNINTEQSGFIITIALDDFKFMNETFGTKNGDIALKEV
                     GKYLIQIHDVNHVYRIGGDIFSIVVNSQLGIEPDDIIRKIEERFKKPWLVEEISFNLA
                     TSIAVVYYPENAETTEDVIVAIDFSIHEAKRSESRRVVYADASISEKIKKKHVIKNCL
                     KEALKNDGFEVYYQPIFSNSRGRFTSAEALLRLEHKELGFIPPDEFIPIAEQTGLINS
                     IGLVVFEKVCRFIASDEFENLKLDNIAVNLSVVQCMQKNLADDLLYLMNKYNVSPTKF
                     KLEITETVAMGSFNIIKETMERLIDLGVKFALDDFGIAYSGVTNMLSLPFSVIKLDKS
                     LIWSMNEDSRHKLTVETIIALINKLNMKAVAEGVETIKCAEDLIAMECEYLQGYYFSK
                     PVPEDVFKNLLKENTFTS"
     gene            53941..54351
                     /locus_tag="KOU88_002047"
     CDS             53941..54351
                     /locus_tag="KOU88_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK3211936.1"
                     /translation="MNKKKILVPIDGTERSMHSLEFIKGIFKKDEVEVEIMNVKELVF
                     IDGISLAEEIKNSENLGRRILDKAAEIMGEYDVKVHFTFGYPGDEIIRKAKEDNVDFI
                     VMTKSTKKGLTRMIGSVTASVVKQAKCIVMIVPE"
     gene            54373..54675
                     /locus_tag="KOU88_002048"
     CDS             54373..54675
                     /locus_tag="KOU88_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIBC"
                     /protein_id="HBK3211937.1"
                     /translation="MNKKIVAVCESERSLNSLKTAANDLGFDLVYEIQENDNIKNELS
                     IYDIEDASIVLFVTSDSIESIEKIDRFIDREFYEVDPKYIIEDAKSIVSEILIDLN"
     gene            complement(54892..55584)
                     /locus_tag="KOU88_002049"
     CDS             complement(54892..55584)
                     /locus_tag="KOU88_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBK3211938.1"
                     /translation="MKSLNATEKIIDYIKLNILNGTFKINSKLPSERKIADLFNISRI
                     PVRNAINILCKEGILRAVPYSSPIVEGFKKVDLFDDGEIYKNHNIQEFYVESLRARQL
                     IESEATKLAILNATSKELQKIKYTYLKSIEELDKVSHGLIEECYDADLQFHKEIILAS
                     HNPIFIKYYELIPKTVSSNQYFGFKYRNSLKDMISHHNKIMMAFDSKDSYLGYTSMYN
                     HLEDVIQLFQHD"
     gene            complement(55610..56797)
                     /locus_tag="KOU88_002050"
     CDS             complement(55610..56797)
                     /locus_tag="KOU88_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3211939.1"
                     /translation="MKKISNQKLLLLSIVTFFWFSQYVYIPFQNPYLSACNVSTNMIG
                     IIIGAYGISQCLLRLPVGVFADSINKHKIFILSGIFFAGLASLIRVFSPGGNGFLIAN
                     ILSGISSSTWISYMVHYTNFFSTEHQQRATSTIILVNNLGMLIGFVMSTLFYEKLGMT
                     ALCIMSVLSSVIGTILALNIKNHNSKKIPEKISIKKYLSICKDKRLVFFSFMALIQQG
                     IQMSTTMSFTTQILKNLGSSSTLIGLSSIFYMVCAVASSGFASTKFCTKYGPKFWIPL
                     VFILVSAYCFLVPTIKNINIIFVLQVLPGISTGILLSYLTSESMKNVPKHQKSTAMGF
                     FQAIYAIGMSVFPMIVGKISEYTSIQYGYFILAIIAILASILSYTYYKKVDLTLNYDI
                     IQS"
     gene            57133..58932
                     /locus_tag="KOU88_002051"
     CDS             57133..58932
                     /locus_tag="KOU88_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3211940.1"
                     /translation="MDYKNIAQEILLNVGGKENVNEVTHCMTRLRFKVKSASKVNKDK
                     LSKTEGVITVVESMGQIQVVIGNKVKKVYDEVIKIVPQSNNVGKKNESQEKQGIINSI
                     LSAVAGIFTPTIPAIAGVGMIKGILSVLAMYYMNKNGVDIKETQSYIILNAMADSIFY
                     FMPIILGYTAAKVFNANKIISMVLGATLCYPTFTALMAGEESVRFLGLAVTKATYTSS
                     VIPIIIAIWALSYVEKVLEKYIPEVIKIIMVPTLSLVVMLPATLFLFGPIGIYIGNVI
                     NFSYKYIYELSPALCGAFVGGLWCVLVIFGAHRALLPIGISDVAQTGRQNLLAFAGSA
                     NFSQAGAALGVFFKTKNQGLKTISMSATITALFGITEPAIYGANLRLKKPMVCAVICG
                     AFGGAIMGMGGAYGNAFANQGVLTIPVYAEAGALGFLSYLGGCAIAFFGSAISTYLVG
                     FEDLEESSNKENSSIKVETKDGVIDITSPVEGECIELSEVKDDVFASKAMGEGIAVLP
                     TKGVITAPTDCEVASLFPTLHAIGLKLDNGAEMLIHVGINTVELNGKYFTKHVNQGDL
                     VKKGDKLISFDIDKIKKAGYDVTTPVIVNNTFD"
BASE COUNT        22181 a         7009 c        10507 g        19272 t
ORIGIN      
        1 aatttataga tgatgaagaa atatcaaaat cttatattat agtaagaggt acttctttgc
       61 caaaatctat agaaaagcaa taccaaatcc aaagagaata ggcggagaaa aaaataaaat
      121 aaattcaaga gtaatagaag agttttatag gataaagaac tgagaacttt ttatataatg
      181 aaaaatagaa ttttaagaga aaatgattta ataaatgatt taacatggtg ttttagcagg
      241 taaaaataaa tcaccagtaa tgattataga aaaattactt tatgaatctc aaaaaactta
      301 gttaagagta agagatttga taagataact aaagttgggg aaatgtgttt gatgagataa
      361 aaaattagta aaatagtata atctaaataa ggatattttg ttgattaaac tacactaata
      421 gtaatattgt agggggaaaa gatgagagaa gaatcgaact ctttaagttt agaccatata
      481 gaaattttct ttgaactttt atctcaaagt acagaagatt atatattttt ttgggatata
      541 aataggaata aatttaaaat ttcttcagca atttttgatg aatttaactt aagtaaagag
      601 atagaatctg atttggtcaa ttgttggagt aaaattgttt atccggatga tgttcaaata
      661 tggaaagatg atatacaaga attactacat ggaaaaaaag gtgagcacaa tttagaatat
      721 aggttgatta ataaatatga agaaatagta tggatttctt gtagaggtaa agtttatgtg
      781 tcggatgacc caaaaactat atttctagtt gggagaataa agaatattgg tgaaaaaaat
      841 aaatttgatt ctatcacagg aacgtggaat agagaacaat ttgaacatag aataaattat
      901 cttataaaag agaaaattta taaaaatggt gctatgttta tcatggatat tgataatttt
      961 aaaaatataa atgagaaata tggacattct tatggtgaca aagtattgcg tgcaattgct
     1021 actgaagtat tagaatatct tccaaaagat gtaagattgt ataggttaga tggagatgaa
     1081 tttgcatttt tttaccctat gtgcactaaa gaaactatag agaaaatata tgaaaagata
     1141 cagatgtata caaatactca gcatgaaatt gaatcaaata agtactattg cacagtgact
     1201 gcaggagttg ctatgtatcc agaagatgga gataattatt tagatttatt taaacatgct
     1261 gatattgcat tggatatagc aaaaattagt ggtaaaaata gaattaagtt tttttcacaa
     1321 gagctctatg aaaataaact aaaggtaatt tcaatgcaac aaaaactaag agagtgcgtt
     1381 gaaaacaatt ttaatgattt tgagttgttt tttcaacccc aggtaaatgc tgttacaaaa
     1441 gaggtaatag gggcagaagt acttttaaga tggcattcga gtacttatgg agaagtatct
     1501 cctgttgaat ttataccaat actagaacag agtaatttaa ttataccagt tgggaagtgg
     1561 attataaaag aagctgtaaa acagtgtaaa gaatggcata aaataaatcc agactttaaa
     1621 atatctgtaa atgtatcgta tattcagtta aaggaagatt tttttagaga ttttatagta
     1681 gaatgtttag tagagtatca attaagacct gaatttttaa ttttggaatt aacagagaat
     1741 tgttggatac cagatataaa tttactaaat gataaattta ttagtttaaa gggtatagga
     1801 gtatatattg caatagatga ctttggtaca ggatattcat ctttaaatta ccttaaagaa
     1861 ctgtctgtta atataataaa aattgaaaga agttttgtta agaatattac atataatagt
     1921 tatgaatata cttttcttga atatattatt aaattagctc atattataaa tttaaaagtt
     1981 tgtgttgagg gaatagagtc ttatgaagag tatgatatag taaaaagctt aggtgtagat
     2041 attattcagg gttttttatt tggaagacct gtaagtgcct ctgaatttta taaatttcag
     2101 ctatcaaagt gatgtatata aaatgagata tatagtatat aaaaataggg caaagtggaa
     2161 gttttgaagt ttattaaaaa tttacacttt accctatttt gttatgtctt ctataaagga
     2221 ttaatatact acactaacta ttatatactt tcactccaaa tttagagatt atttcactag
     2281 ctttttggac atcttcctta gtggcatcag gaacatcttt tagttcataa tcgataccta
     2341 aactttccca tttgtgtatt cccatagaat ggtatggtag caattcaaat ctttctacat
     2401 ttttcaatgt agctacaaat tgacctagtt tttctaaatt atctatatca tcagtaatgc
     2461 caggaactaa aacatgtctt atccatacag gaatatttct tgattctaag tgtctagcaa
     2521 gttttaatgc cttatccata ccaacaccag tcaaatcaat agatttttcc tcaaccatat
     2581 gttttaaatc aagtaaaacc aaatcaatat tatctaaaac tgggtctata gtttctatat
     2641 ctacaaatcc agatgtatcc aagcaagtgt gtatatcatt ttcttttgct tttttaaata
     2701 attcacttaa aaattctggt tgaagagtgg attcaccacc agaggcagtt atacctccac
     2761 cagaaaactt cataaaagaa gtatacttaa gagcatccgt tattatttca tcaactgtgt
     2821 attcttttcc tgatttaata tcccatgtat ccctgttatg acagtatttg catctaagag
     2881 gacacccctg aaaaaataat atatatctta ttcctggtcc atctacagta ccaaacgttt
     2941 ctatagaatg tatctttccc ttaatcatag agttcacctc acaatatatt ttaataacct
     3001 tatcaatagt tataatattt ctctaaaaaa ggccatctta taccagaaat aattcaaata
     3061 taagatagcc ttttattttt attttttaca cagtagtaat cttagttaaa gtataaaaat
     3121 ttaaagacta agccatttta ccgtggaatg ttctgtttat aacatctaat tgttgctctt
     3181 tagttaattt tatgaagtta actgcatatc cagatactct tatagttaat tgtggatatt
     3241 cttctggatg ttccatagca tcttctaaag tagctctatc aaatacattt acatttaagt
     3301 gatgagcatt ttgagcgaag tatccatcca tcattgcaga aagattgttt attctttcag
     3361 tcatatcttt tcctaaagca gcaggtacta tagagaaagt attagatata ccatcttgag
     3421 catgttcata tggtaattta gcaactgaag ataatgaagc taaagcacca ttagtatctc
     3481 taccatgcat tgggttagca ccaggagcaa atggagcacc agctcttcta ccatctggtg
     3541 tattaccagt tttcttacca taaacaacat ttgaagttat tgtaagtata gattgagttg
     3601 gataagaatt tctataagtt ttattctttc ttattttatt cataaagctt tcaactaact
     3661 ctacagctat actatcaact ctatcatcat tatttccgta ttttggataa tctccttcta
     3721 tttcaaaatc aacagctatt ccttgttcat ttctaatagt tttaacctta gcatgtttta
     3781 tagcagataa tgagtctgca caaactgata atccagccat accacaagcc atagttctaa
     3841 atatatctct atcatgtaat gccatttcta atgcttcata agaatattta tcatgcatat
     3901 aatgtattac atttaaagta tttacatata atgttgctaa ccaatcagtg aatggttcaa
     3961 atttactcat aacttcatca taatctaagt actcagaagt tataggttca aatcttggtc
     4021 caacttgaac accagatttc tcatctacac caccatttat agcgtataat aaagttttag
     4081 ctaagttaac tctagctcca aagaactgca tttgtttacc aattctcatt gcagatacac
     4141 aacaagctat accatagtca tctccccagt atgctctcat taaatcatca ttttcatact
     4201 gtactgaact tgtatctata gatactttag aacagaaatc tttgaatcct tgaggtaatt
     4261 tagttgacca tagaactgtt aagtttggtt ctggagaagg tcctaatgta tatagagtat
     4321 ttaacattct aaatgagttt ttagtaacta atgttctacc atctattccc atacctccta
     4381 tacactcagt tacccaagtt gggtctccag agaataggtt attgtaatca ggagttctta
     4441 ggaacttaac cattcttaat ttcataacaa aatgatccat atactcttgt aattcttctt
     4501 ctgttacgat tccagctttt aagtctcttt caaagtatat atctaagaaa gtagatgttc
     4561 tacctaaaga cattgcagca ccattttggt ctttaacagc acctaaataa ccaaagtata
     4621 accattgtac agcttctttt gagttagttg ctggttttga gatatcaaat ccataagatt
     4681 cagccatttt tttaagttca tttaaagctg atatttgctc agttatttct tctcttaatc
     4741 tgataacttc ctcatccatg caagaaactt ctaatgattt cttttgctca tttttatctt
     4801 ctattaaagc atcaacaccg tatagagcaa ctcttctgta gtcaccaatt attctacctc
     4861 taccataagc atctggaaga cctgttatta taccagattt tctagcagct ctcatttctg
     4921 gagtataaac atcaaaaact ccttggttgt gtgtttttct gtatttagta aatatatctt
     4981 ttatttctgg gtctaattca tatccaaaag cttcgcatga attttcaacc atctttatac
     5041 caccatatgg catgacagct ctttttaaag gggcatccgt ttgtaaccca actattgttt
     5101 ctaattcttt atctaaatat cctggagcat atgcagctat tccagaaaca gtttttgtat
     5161 caacatctaa agtaccacca ttttctcttt cttttttaaa taggaccatt gcttcgtccc
     5221 ataatttttt agtattttca gtggcaccag ctaagaaaga gtcatttccc tcatatggag
     5281 aatagtttaa ttgtataaac tctctaacat ttatttcttt agtccatctt cctgttttaa
     5341 atccttgcca tgcattcatt aagtatttcc tccttagatt taaatgataa ataatactat
     5401 taaaattaat ttttatatac ttaatttatt ttatatattt ttttaaaaat atattttcta
     5461 atataataat agcatattat tcgtatcctg tatacataaa aaataaaaaa ttgtcgcttt
     5521 aaagtataaa acagattata tgttaataat gtggtgaaat tatacccata tataaataaa
     5581 ataaaacaaa taaatagcta attaaggaga aaatattttt tattttttgt ttaggataaa
     5641 taaattttat tatggaaaaa agaaaaagca tacatcttca caaactgaat atttatttaa
     5701 tagggggagg tgatagattg tttatcacag tggtattatt tttagtaggt ttcctattaa
     5761 ttactaaagg cgcagatatc tttataaatt gtactgtaga gataggtaaa aaaacgaata
     5821 tatcagaaat tatacttgga gctactatag ttagttttgc aacaacatta cctgaattta
     5881 cagtgtctct acttgcttct attgatggtc atactactat gagtttagga aatgcagttg
     5941 gttctataat atgtaataca gggttagcat tagggttggt tgtttttata agtccattta
     6001 atgtagataa aaaaatgttt ttttctaagt ctttactatt aatagtatcc gttatagttt
     6061 taattttatt gagtttagat ggagttataa caagaggtga ttcattatta cttataataa
     6121 tattaatctt ttatatggtt aataattata gaagtgtcgt tggaaaatct gatactaaaa
     6181 atagaaatat taaaaataac actattaaag acatatctac taaaaaaggg aaaaattata
     6241 ggggtttttc cgtattagaa attgtaaaaa tactattact ttttgctaca ggattgataa
     6301 tgatgataat aggttcacaa atccttatag agagtggagt aataatagct agttttttaa
     6361 atatacctca aggtatagta agtttaacta taatagcact tggaacttct ctgccagaga
     6421 tagtttcgtc gattactgct ataagaaaaa atcatcatga aatatcagta ggaaatattt
     6481 tgggtgcaaa catattgaat atagtatcag taatagctgt atcagcaata ccaaataaca
     6541 taccaatact atctcaaaat agacaattgg atataccatt catgatatta ttattattaa
     6601 cagtaataat accaacactt aaatctaata aacttagtag aatacaaggt atattgatgt
     6661 tattcacata ttttctgtac atatcaattt tgtatttcat gtatattatt taactatact
     6721 gtttaaaata ttaattgcag aatatcctaa aaaagtatat aatggatagg ttaagattaa
     6781 ttgataacgg agaggaataa tatatgaata taacaaagtt tgaagattta ccaataagtg
     6841 agggaataaa aaaagctata gctgaaatgg ggtttgaaga accatctcct atacaagcac
     6901 agtctatacc tgcgattttg tcaggtaaag acgttatagg acaagctcaa actggtacgg
     6961 gaaaaacagc tgcttttagt atccctatac tagaaacaat agacccaaat aatagaagtt
     7021 tacaagctgt agtgctttgt ccaacaagag aactggcaat acaagtatca acagaaataa
     7081 gaaagttagc taagtattcg cacggaataa agacattacc tatatatggt ggtcagccaa
     7141 tagatagaca aataaaatct ctaaagagtg gtgtgcaagt tgtaataggt acaccaggac
     7201 gtacaataga ccatatcaat cgtaaaacat taaagatgga taatgtaaaa atgattatat
     7261 tagatgaagc agatgaaatg ctagatatgg gatttagaga agatatagaa atgattttaa
     7321 gtaagattcc agaagaaaga caaacaactt tcttttcagc tactatgcca agaggaattt
     7381 tggaattaac taagagatat caaaaagacc cagagcatat aaaagttgtt agaaaagaac
     7441 ttacagtttc aaatacaaag caatactata tagaaactag gtcatcaaat aaattagaag
     7501 tattatgtag attagtagat gtatatgacc ctaaactatc tgttgttttc tgtaatacta
     7561 agagaaaagc agatgaattg gtaggagatt tacaagcaag aggatatttt gcagatgcat
     7621 tacatggtga cttaaaacag actcaaagag atatagtaat ggataagttt agaaatggta
     7681 caatagatat acttgttgct actgatgttg cagctagagg tatagatgtt gatgatgttg
     7741 aatgtgtatt caactatgac ttaccacaag atgaagagta ttacgttcat agaattggta
     7801 gaactggtcg tgctggtaga gaaggtatgt catttacttt tgtatttgga aaagaaatga
     7861 gaaagatgaa agatatagaa agatatacta aatctaaact aataaagcat aatataccaa
     7921 caataactga tgttgaagag aaaaaagtag gtactttctt tgcacaagtt aaacaaacta
     7981 tagaagaagg tcacttaact aaacaattac aatggttaga aggtttctgt aatgatgaag
     8041 attatgcaat ggttgatata gctgctgcac ttgtaaaact atctctaggt gaagaaatga
     8101 aagaagaaat aatagaagaa aaacctagaa gagagcgtgg agatagaaaa ggtggtactg
     8161 gagctaaaga tggtatgatt agattattta tcaatattgg tagaaatcaa agagtacaag
     8221 caaaagatat agttggtgcc atagctggag aagttggaat accaggtaaa gtagtaggta
     8281 ctatagatat atatgataag tatacttttg ttgaaatacc taaaaaagat gcaaaaacag
     8341 taattgaaaa gatgaaagat attaagataa aaggtaataa gattaatata gaaaaagcaa
     8401 ataagaagaa aaaataacgt atagtataca aaactataat tagaaaatat ataaaataat
     8461 atattggata tttaaaaagc ctgatgtgtt ttcaaaacag atagtagata atctgtaaga
     8521 gttaacagca taaggctttt cttgttttat ataaggaatc tgaataactt actgttaaat
     8581 ctttgaatta ctgcacctca tttacgttaa ggatggagta ttctacctat ttttgataaa
     8641 atatatctat gttttatata ctgtagtttt gaatatataa agtttaataa attatagtat
     8701 atatgttaat ttttaataag gtaagaaagt agaaagaagg atattttatg gatataataa
     8761 aaaaattaag tcatgggtgt acattagatt gtcatgactg ttgtaaattc aatgtttata
     8821 ctaaaggaaa taatgtagta aaaattgaag gagataaaaa tcatccttat acaaaaggtt
     8881 ttatatgcaa aaaagggatg gcccatttag atagattaaa tcataaagat agaataaaga
     8941 ctcctatgct taaagttgat ggagtatgga aagagatttc ttttgataaa gctatagaaa
     9001 taatggcaga aaagcttaca tactataaag aaaagtatac atcaaagtct gtcatgcatt
     9061 atgaccaata tggaagtggg tctgtgctaa aatacatagg agatatattt tttaattttt
     9121 atggaggtgt tagcagacat aaaggtggtc cctgttggag tgcagggatg catgctcaaa
     9181 aatatgattt tggagtagct aagagtcatg ctatagaaga tatgttaaat agtaaaagta
     9241 tatttgtgtg gggaaaaaat ccagcatata ctacaattca tactatgcaa ataattaaaa
     9301 aagctaaaga aaaagggata aagatagtag tgattgaccc catatataca aaaacagctc
     9361 aaatagcaga taagtatgta caagtaaatc ctggaacaga tggagcttta gctatagcta
     9421 tggcaaaaat tatagtagaa gataaattat atgatgaaga atatataaac tcgtatgtta
     9481 ttggttttga agaatataaa aaatatttat cttcattgga attaagtttt ttaattgatg
     9541 aatgtggtgt taaagagaat gatataagag agttagtgga tttatatact aacaaatatt
     9601 caagtataaa tgttggatat gggcttcaaa aatataaaaa tggtggaaac acaataagag
     9661 caatagatgc tttaggtgct ataactggtc aaataggatt tagtggtgga ggggtaaact
     9721 atgctaataa agtttatccg agtgttataa attctgaccc ttacaatagc caatcatatg
     9781 gtgaagatag ggagttttat gtaagtaata tcagtaaatt tatagaagaa tctttaaaaa
     9841 atacatcaaa taaagtaaat tatgcatcag atgaacttga tatgacatca aataaagtaa
     9901 attatgtatc agatgaactt gatataacat caaataaaac agattatata tcaaatgaat
     9961 tgtataattt atctaataag tcaatcaaag gtaatattcc tataaagatg gctgtaataa
    10021 ctaaaagtaa tatgctgaat caactgccag atttagtaga attggagagg gtgttttcaa
    10081 aaattgaatt taaagtatgt tttgatatgt ttataactga tacagctact ttatgtgaca
    10141 tgtttatacc gtgtacaaat acactagaga gtgaagatat aatttatagc tcaatgacca
    10201 atccatatat aacctataat gaaagagctg taaagccagc acataaattg atggatgaat
    10261 attacttctt tatggagcta gctaaaaaga tgggattaaa tgattatcct tttgtagaaa
    10321 agagaactta tttagaaaaa gtgattgaac cacttaagcg ttttgacaaa aatctggata
    10381 tagaaaaact taaaaacaat tactttacta tacataaccc tgttgcttgg gaagataaga
    10441 agtttgagac tccatctgga aaatacgagc tttattcaga aagtataaaa aacttgggaa
    10501 taagtccaac acctgtatat ataagcaata aatataaaga aatagaagat aaaaatattt
    10561 cttttagatt attaactaat catcatgcag atactttatt tagtcagcat tttatggaca
    10621 aaaaatctat agctcaagca tatataaatc ggagaatggc taaaaaagta ggtattgagg
    10681 acaaagatat tgtgatattg aggtcaaaaa aagcaaaaat aaatgtacaa ataaatatag
    10741 atgatggagt aggtaattat atagtaaaaa tgtatgttgg ttggtggaag aaacatggaa
    10801 atcctaatag tttaacagac actggtatat cagattttgg gggtcaggta acatataatg
    10861 aaagtatggt agaaataata cgacaaaact agttaaattt cattgaagga ataaaaatat
    10921 aattatagaa ttgattaaaa gttactattt ttacaaaact attgaaggag ggatttttga
    10981 tggtaaatta ttccttagaa cataagaatc tatacataga atttatgtgc tcagaactag
    11041 accaccatgt agccaatgaa ataagggaag aaatagataa cttattaagt gtaaatcaag
    11101 taaaaaatgt tgtatttaat tttgaaaata ttaattttat ggattcttca ggtataggcg
    11161 tcatcatagg tagatataaa aagatttcta atgaaggggg acgagtttca gtaattaata
    11221 taagttcacg agttaagaag atttttgatt tatctgggtt aaataaaatt attggcattt
    11281 atgatacgta tgaagaagct ctaagttctt tgtagggagg agtatgtgat gaataatatt
    11341 atggaagtta aattttcggc aatatctgaa aatgaaagtt tagcaagagt tatagtagca
    11401 tcctttgcag ctaagttaga cccaacagta gatgagttag tagatataaa aactgctgtc
    11461 tctgaggctg ttacgaatgc tataatacat ggatatgaag aagacagttc taagtttgtt
    11521 ttcttaagat gtgagataga aggaaatact ataaagatta tagttgaaga tgaagggtat
    11581 ggaatagaaa atgtggagaa ggcaatggaa ccactttata catcaaaacc agaacttgat
    11641 agatcaggaa tgggattcac agtaatgaaa agctttatgg acgatgtaga ggtaagttct
    11701 gtaaaagata atgggactag aattgaaatg actaaaaaaa taaatgtgcc taaataaagt
    11761 ccaaaagtga ggttttatta tggaagtaac tgttgccaga gaagaaaaaa aacctcttct
    11821 tagtcatgaa gagactctag aacttattga aaaagttcaa aatggagatg aagaggcaaa
    11881 agaaatatta atatcaagca atttaggtct agttaggagc gttgtatcta gatttttaaa
    11941 tataggatat gatagagaag atttatttca gttaggttct ataggcttaa taaaatcaat
    12001 atataaattt gacccaaaat ttaatgtaaa attctctact tatgcagtac caatgatttt
    12061 aggtgaaata aagagatact taagagatga tggtatgata aaagtatcaa ggtcgttaaa
    12121 gcaaatagct ataaaggcaa agatggaaag tgaagcttta actaaaaaat taggtagaga
    12181 gccgagtata gaagaattag ctaaagcaat agatgtagaa aaagaagatt tagtaatggc
    12241 tatggaagct aatttcaatg ttgagtattt gcaaggagtt attcatgaag aggaaggttc
    12301 tccaatatgc cttattgata aaataagcat gaaaggagaa agtgaagaag aaaaagtagt
    12361 ggataacata ttgttaaaag acatacttgg aagactggat aagagagagc gtcaaataat
    12421 agttctcaga tactttgaag acatgactca aagtgaaata ggagagatgc tcaatatatc
    12481 acaagttcaa gtatctagga tagagaagaa agtattgtct aagttaaaag aatatatatc
    12541 gtgataatac ttatgatatg tagaataata aaatataata aatatattac taaaataaaa
    12601 tgtaataact ttttatgtta agtttttaaa ttattaaaag atattaaaat aataaaaagc
    12661 attaaaaaag taaaaatata aaaacaaggt gtctttatgg aaaaatagat tttttcttta
    12721 ttaggcatct tttttatttt ttgaccaaac tttagatagt caaaataaat aataggttta
    12781 tttttttaaa attaacaaat aatactttag agaggtgttt agtatggata aaaattataa
    12841 aaaatatgta gaccaaataa gcccaaaacc tacatattta aaaaactata cacttgcatt
    12901 tattgtaggt ggaattattt gtatgatagg gcaagcaata aatgatttgt atatgaaagt
    12961 tggaggtctt gataaactag gtgctagttc tgcaacatca ataacattaa tatttatagg
    13021 ggcattttta actggattag gagtttacga cctaatagga aaaagagctg gagctggttc
    13081 tataattcca ataacaggtt ttgctaactc aatagtatct ccagcaatgg agtataaaag
    13141 agaaggctat gtattaggtg taggtgcaaa cttatttaaa attgcaggac cagttttagt
    13201 ttatgggata ggttcttcta ttttatgtgg aattatttat tatattttta agatgtttta
    13261 gatgattttt atttaattta aattttatta attatgaaga aggtataaaa tctgaaaata
    13321 gctactaaag taactaattg aaaaataatt ctgcagattt aattaatatt tttaattaat
    13381 attaaaaatt tgaatagtaa aatgcaaaat taaaaaggtg tgaaaatatg aaaaataaaa
    13441 gaattggaaa aagaacagtc aagttagaaa ataaaccaac cataatatca actggaacta
    13501 tagtaggtcc taaggaaggt gaaggaccac taaaggacta ttttgatatg attatgactg
    13561 acgatttata tggtgaaaag acttgggaat tagctgaaag taaaatggta gagactgcat
    13621 ctcaacaagc tatccaaaag gcaggtaaaa aattgtcaga tgtaaattat atgctaggtg
    13681 gcgatttaat aaatcaaata gttccagcat cctttgcagc aagagaactg gctattccat
    13741 ttttaggtat atatggagct tgttctacaa tggcagaagg tctttgtata ggttctatgc
    13801 ttatagatgg tggttttgct gatttagtac tgtcaggtac atcaagtcac tattgtacag
    13861 cagaaagaca atttagattc ccacttgaac ttggaaatca aaaaccaatg acagcccagt
    13921 ggacagttac aggagcagga agtgtattat tagctcctaa tggagacggt ccaaaagtaa
    13981 agtatgttac tgttggtaaa gtaatagatg agggtattga tgatggtaat aatatgggac
    14041 cagctatggc tccagcagca atagatacta tctactctta ctttgaagat actaatgatg
    14101 acccaaatag ctttgatata attgctactg gagatttagg tactcttgga aaacagatag
    14161 cagaagactt tctaaaagaa aaaggtgtag atatatcaaa agtttatact gactgtggta
    14221 tagagatgtt taaccttaaa gaacaagatg tccactgtgg tggaagtgga tgtgggtgtt
    14281 cagctacagt gtttgcagga tatatatatg ataagttgag aaaaaaagaa tttaacaaag
    14341 taatgcttgt atcaacagga gcactacttt caccgacaag tacactacaa aagcagacaa
    14401 taccatgtgt tgcacatgca gtagtaatag taaatgagta ggaagtgata taatatgtta
    14461 atggactatg taagagtatt tattgtaggt ggaattatat gtttaatagc ccaagtaatg
    14521 atggattatt tcaaaatgca aactccatat gttatggtaa cgtatgtaac aactggtgta
    14581 gttttaactt ttctaggact ttatgagcca ttagttaagt ttgcagcagc aggtgcaaca
    14641 gttcctataa taggatttgg atattcactt gctacaggag taataaaatc aattcaaagt
    14701 gatggttttt taggtatttt tttaggaggt acaactgcta cagctggtgg aatagcagca
    14761 gctatattct ttggatatat tatgtcagta gtatttactc caaaagcaaa accataaatc
    14821 tttattaaaa gaataataag tttttgaaat aataactttt tataaagcag gtggatatct
    14881 tttagattcc acctgttttt tatataaaga agcgtttaca taattgaagt tgacaattat
    14941 ttacaacata gtgtagtatt atattatcaa aataaaatga agtgaagtag gggataaaga
    15001 tggtaactat taaagatatt gcaaggaatc taggtatcag ttattcaact gtttctaggt
    15061 gcttaaacaa taatcctaat gtatctgaaa aaacaaaaaa gaaagtggta gaagaggcaa
    15121 atagactagg gttccatttt aatgtaaatg caagaaattt agcaaaaaaa gaaactaaca
    15181 ggataggggt aatcttttca aataatttta atcatcaaga tactagaaag ttttttagtg
    15241 atataatgga tagttctata aattctattg agactaataa atacgatttt ataatacagc
    15301 ctaataataa cattagtggt gatagtaatg tatataaaat ggtaaatgga caaatggttg
    15361 acggattagt aattgtgtct caatcaataa aaaaagaaga gtatgatttt ttaaaagaca
    15421 ataattttcc acatgtattt atatatttta aaccatcttt tataggagaa gtagataatt
    15481 tcttttggga cgataacgtg tatggaggtt atatagctac caagcattta attgaccatg
    15541 gtcataaaga tataataaca gtaacttcag atgataagag ttcaaaaatg catgaagata
    15601 gaaccaaggg atatttgaat gctatggaag aagcaaattt aaagacagaa gtcattaaat
    15661 ctaaaatgga ttttgaatct caagttgaat ttttagaaaa atacattgat aaaataaaaa
    15721 aagcttcagc tatatttgta caacaagatg taccagcgat ttctataata caagagttaa
    15781 aaactactta tggtataaat gtaccagaag atatttccat aatagggtat aataatattg
    15841 aattaatatc atattttagg tcgcatttat caacaataga tgacccaaga gagcaagtta
    15901 taaaaaatgg agtagatagt ttagtaaata taataaataa aaagagtaca gaacacattc
    15961 caagaaaatt atatccaagg ttaataatac gaaatagcgt taaaagaata aagtagtaag
    16021 cttttaagta tcaaacgttt attaaaaata ttatagatta tgtgaagttt tttaacaaat
    16081 aatataaata aaaattaaaa ggagtaggtg tatataagta cattgtactc ctttatttat
    16141 tgagatagtt tttataatat gaatgaataa ttttattcaa ttatttgaaa atccgttatt
    16201 ttaacaatat aaattaataa attatttgta ttttatatca tgaatctata atattttttt
    16261 gattcataac taaaagtata taaaaatgat gaataaatat atattataca ttatcaatga
    16321 taggttatat aataaaatca ctaacaatta tattataaga aaattataaa aattacaagg
    16381 aggtatagaa atgaaagaaa aagcagggat tagaaatgcc ataatagcag cctttataat
    16441 cacaatattg gcagaattaa ttggacctat ttcatttaaa gttatgggaa ttaatgtaac
    16501 tttacttagt atactatggg ctatattcat aggaatggct gtttctcctc atttattagg
    16561 gagagttata ccagccttaa aaaagtttat aggggataat gaaataaatg tatctccata
    16621 tttattatct ttgacactat atccattagg gataatgttt ggaattaatg cagggcctaa
    16681 agttggtata ttacttcaag caggaccagc acttttatta caagaatttg gtcatatggg
    16741 tacaatgttg atagcattac ctgttggagt agcattaggt cttggaagaa gtgcattagg
    16801 tggtactttt tcattatgtc gtgacacagc actaggaatt attggagata agtatggatt
    16861 aaactcacca gaaggtatag gaacactagg aacttacata agtggtagta tatttggaac
    16921 attattattt tcatttttag caccagtggg tgtactttta ggatttcatc catatgcttt
    16981 agcaatggca tcaggaatgg gtagtggttc aatgatggga gctgcaacag catcattaat
    17041 gaatacagtt ccacaaatgt cagagcagat tttagcatat tcagctacta gtggattgat
    17101 tacagctgtt actggaatat atatagaatt attcttatct ttaccagtag ccaactacta
    17161 ttatagcaaa gtagctccag ttattgaaag atttagagga agaaaaacaa gaagaacaag
    17221 taataaattg taaaggagga tatatatatg gaaaaaactt ttaagactat tatggagcag
    17281 ataaaaatag tattgtttat atatattatt atttgctttg gacaaatgat agcacttaag
    17341 actcaggctc aagatttgtt gattggaagt gtatctggat ttttgttggt gataattgct
    17401 attataataa agaattttgt taaaaaacct aatttaccag gttttgcatg ggctacatta
    17461 gttgcatttg ttttatcgct tccaatatct ccagtggggg atatcatagc aacaaatgta
    17521 gggaaaatca attttatgtc tacagtaaca ccattattag cttttgcagg aatctctgta
    17581 ggtaatcaat tagatatatt aaagactttg agttggaagt tagtagttat atcatttata
    17641 gttatgacat ctacttactt tggttctgct tttatatctc aaacagtttt aagattaaat
    17701 ggaatgcttt aaggaggtag taaatatgaa tgaattaaaa gcaaaaatta aagaggaaat
    17761 aaagttatta tctgaagaga aaaagacatc atttgaaaaa gtttctgact atttattttc
    17821 aaatccagaa ttagcatttg aggagtataa gtcacaaaaa gcattatgtg atttgttaga
    17881 agaaaatgaa tttaatgtaa ctaaaggtgt aggaggatta gaaacatctt ttgaagctgt
    17941 gtattcaaat ggaactaatg ggaaaacagt tgctttttta gctgaatatg atgcacttcc
    18001 aggaatggga catgcatgtg ggcacaatat catagggaca agttctgttg gtgcaggtat
    18061 catattaaaa gaaatcatga aaaaacataa tatagaaggg actgtaaagg tttttggaac
    18121 acctgcagaa gaaagagtag gtggaaaaat aactatgatt aaagaaggtg tatttaataa
    18181 tgtagatgct gcattaattt tacatccaag tgatgcttca atgcctgatg atatatcatt
    18241 tgctcaagtt aatttaaaat ttgattttac tggtaaggca tcacatgctg ctgcttttcc
    18301 ttgggaaggg aaaagtgcct taagtggagt aatagcacta tttaacagtg taaatagcat
    18361 gagattacat cttaaagatt atgcaagagt acatggaatt ataactgatg gaggtagcat
    18421 acataatata attcctgaaa aatctacagc tatatttaat gtaagagcct taagtataga
    18481 atatttaaat gagatttgtg aaatgcttaa aaattgtgct aaaggagctg caatttctac
    18541 tggaactaat gtagaaatag ttcaattaga tgaaatatac aaagagatta agaatgattc
    18601 tgaattagtg aatatagtta gacaaaattt tgaagttttg ggtgaagact atgttgaaag
    18661 agatttaagt caaggtatag gttcaactga tacaggaaat ttaactcatg agatacctgc
    18721 aatacaagca tatataaaat taaaagaaaa tactgcaact catacagatg aatttgctgt
    18781 tgcagctggt ggtgaagaag gcagagtagc acttataaaa gcaattaagg tgttagcaat
    18841 gtgtggagta gatattttgt atagtaaata atatataatt ttaaaatata ttaagaaagg
    18901 aaatcggatt agacatgata ttaaaacaag taatagaggt ttatgacatt ttagataaag
    18961 caaatgctaa tggggaagaa gtaaaaactt acttacaagg ttatggtgaa gtagatgtaa
    19021 ctgtaaaaga attgtcttca agtaaaggtt caacagattt agtaaagctt acaattcctg
    19081 gaaaaaatgg aaaattaaaa ggtggagatg ctcctactct tggtatttta ggtagactag
    19141 gagggattgg agcaagacca gaagttatag gttttgtctc agatggtgat ggagcattgg
    19201 tagcaattgc agtggctgct aaacttttgg atatgcaacg aaaaggggat atattagatg
    19261 gtgatgttgt aatttcaact catatttgcc cagatgctcc aactaaagaa cactatccta
    19321 ctccttttat ggattctcca attgatatga tgactatgaa tgaaaatgaa gttgatagta
    19381 gttgtgatgc aatactttct atagatacta ctaaaggaaa tagagtaatc aatactagag
    19441 gatttgcaat atcgccaact gttaaagaag gctacatatt aaaaactagt gataaccttt
    19501 tagatattat gcagactgta acagggaaat ctccatttgt attccctttg tctattcaag
    19561 atataacacc atatggaaat aatctgtatc acttaaatag tattttacaa ccagcagtag
    19621 ctacagatgc accaatagta ggagtagcaa ttacaacaga gatgcctgtt gctggatgtg
    19681 ctacaggtgc aactaatttt agtgatttag attcagctgg gagatttgca attgaagttg
    19741 ccaagctatt tggtagaaat aagtgtgatt tctatgataa agaagagtgg gaaatgctta
    19801 ttaagagata tggcaaatta aatagatttc aaacatttgg tatacagtaa ttagaaaaat
    19861 attaagttta tataatttgt gatataacta tttaagaata tataaacaat taggaataaa
    19921 agtaagaata aagcacttag ttaaaaactt taaaaataaa atatttattt gtttatataa
    19981 aaaggaggat tctggttatt gggattctct tttttatgaa tacaaataat atattgtaat
    20041 tataaaaaaa ggagcgtttc aaagtgattt ttttaatcac cttgagacaa ctccttatat
    20101 ttttatttaa attctatttt ttattaagtt gctggagttc caccaccatc aggaggagta
    20161 gtagagccac caccattatt tccaccacca tcaggaggag tagtagagcc accaccattg
    20221 tttccgccat tatcaggagg agtagtagag ccaccaccat tatttccgcc attatcagga
    20281 ggagtagtag agccaccacc attgtttccg ccattatcag gaggtgtaga accgccacca
    20341 ttatcacctg tgttattatt gttattatta ttttcttctg gttggttatt gtctggtttt
    20401 tttgtatctt cagatgatgg ttgagaactt actttagtag gagcagtacc ttcaataaat
    20461 gctgctttag agccagaaga ttgctttcct ccatcctcta aattaatttt tgtaaaatat
    20521 acatttttag gaacttcaaa ttcagtaacc gttaaattag catgtatttt ttccataatt
    20581 ttttcccata gttttgcagt actagtactt ccatgtggta cttctctacg ttttatagtg
    20641 ttaccagaat catcttttct accagcatca tctccaatat aagttgcacc aacataataa
    20701 ggagtgtaac cgacaaacca agcatcatat gcactatttg tagtacctgt tttacctgct
    20761 acaggcattc cctttggaag tgtagcaaca ccaccagtac cttcagtaat tacgctttct
    20821 aacatatctg taacaacata agctacttca gggtctacaa ctttatgttc ttcaggagca
    20881 tttttaacta ataattgacc atcaaaggta gttatagtag taaaaataga aggttctaca
    20941 taaataccgt gatttgccaa tgtaccataa gcagcagcca tttgaagtgg agtaatacca
    21001 ttcgccatac cacctagtgt caatgatggg aattttctat cacttgcttc agatgaacct
    21061 gagtgattat tctttaaagt tgttatacca aagttcttta agtaatccat cattatatct
    21121 acacattcat cataagagtc tccaagcatt tcagcagttt tgacagctat cgtgtttgaa
    21181 gatttagcaa gtgctttacg taaactcata gaaccatgac cagcagtagt agttcttgga
    21241 ttccatttat tattttcttc aaacttatat cctcctcgag aatcacttag agcagttgct
    21301 tgtgttattt ttagagtatc aatagctggc gtatatattg ctaaaggttt tatagaagaa
    21361 cctggctgat gagggttagt agcacgattt aaagtttttc taccacttat atttcttcct
    21421 ccagctagtg ctcttatttc accattttta taatctaaga ttaccattgc agcttgcggt
    21481 tggctaactc catcaggacc gaccatatgt cctgggaaat tgctatttct atcaaattct
    21541 tcttctaaag catcttgcat tttagggtct atagttgtgt ttacaattag accaccattg
    21601 tagaataagt tttgagcttc atcatttgta tgtccttgtt ccattaaagc atttataact
    21661 tcactttcga taaggtcttc tacagatgaa gaaactttat ctgatgattg aggcaatttt
    21721 atttctattt tagctttgat tgcttcatca tattcacttt gttttatata tttcaattct
    21781 aacattttct ttaaaacaat ttcttgtctt tttttagctt caggattact tacagccttt
    21841 ctaacaacta atgtacctgc ttttaattgt ctataagtat cattagatat aagctcccaa
    21901 gattttattt tttcaatcat atcaaagtcc acttgagtag ggtcatctaa atcatcatca
    21961 gttgtgttaa caaaaaataa taatttattc tctaaatcct ccttagtttc atttccctct
    22021 aacttagaag ttttataggc tgaaaatctt gatggatttt tagttgaacc agcaagaagt
    22081 gctgactctg ctagagtaag gtcagctgca gacttatcaa aataaccacg tgcaccagcc
    22141 tcagcacctg ctagacctct accaacgaag aagttattta aataagtttc tagtatttta
    22201 tctttactta ctgttttact catctcatgt gcatagtaaa tatcctttat tttacgaggt
    22261 atagtttgct gttcagttgt taacagcatt ttggatacct gcataggaat agtactacca
    22321 ccttgcttag tacctgtaag ggtctttaat actgacctaa ataaaccttt aatatcgaca
    22381 cccttatgct cataaaaacg ctcatcttct attgcaatta cagcatgttg aagataaggg
    22441 gaaatcttat ctaatggaac gggtgtcttt ttatttacac ttggagctgt agataatgtt
    22501 tttccattag cgtatttaat agtagttgtt tggttcgtct gtttatctaa aacagcttct
    22561 gtaactggag ttacatctct tagtgacgca aatactagac cagcagtacc tgctgtacca
    22621 acaactagta aaactaaaaa tactatccca aatactctta gttttttaaa tttatcgctt
    22681 tttttagatt ttttcttgtt ttttgttgaa cgagtcttgt tagctgaagt tctattaatt
    22741 ggtttatttg tattaccaga tgagctaact ttttttctcc tgattttatt tccattttta
    22801 tcattatcgt tattcataag attttaacct ccttacttaa tgcaatatta taacacaaat
    22861 aggagtagtt ttgtaattaa tagaaaaaat gaatttgcta taatattctg tacattgtat
    22921 atgtataaac gtaatatatt aaaaagtcta tatttttatt ttatttattt ttgacaaata
    22981 ttataaaaat tatgccaaag ctacatataa ataaatagga ggggataatt ttgaatagaa
    23041 tagtagatag aaaaacaaaa aatgaattta gaaaaatcat agctattttt ttagtaattc
    23101 ttttcttgtc tgtatttata ggcagtttta tatatataga taaaacttta agaccgacaa
    23161 taacagtttt agcagagact aaagctcttg aactagcaaa taggtcgata aataaagctg
    23221 ttgctgagat ggtagaagga aaaataaatt atgaagattt aatggatata caacttgata
    23281 ataatggtaa aataactatg atacaagcaa acactataat gatgaatgaa attgcatctg
    23341 caatagcttt agaaatacaa gatgaattaa aaaaggataa gacagcaagt tcttacatac
    23401 ctataggaac agcattagga agtcctatat tagctaaata cggtcctaaa cttgaagtat
    23461 ctattgaacc tataggaaca gtatcagtaa actttaaaac ggaatttgag tcttcaggta
    23521 taaatcaaac tagacataga atatatttag aagctcaaac acaagttaaa gtagtaatac
    23581 cacttataac ttcaacaaaa caaattaaag ctcaaatacc tatttgtgaa actataatag
    23641 taggtgatgt tccagaaagt tatgtaaata ttccagaaaa aaatctagga aatgttttac
    23701 ctaacactgg aaagaatacc aacaagtaat gtaaagttgt atatttttaa ataaattcaa
    23761 aataatagtt tataaataaa atttttggaa ataatattaa tataatttta ataaaaattt
    23821 atattttata ctatgtaaaa tatctaatat atttggtctg taggttaaat aaaagtacct
    23881 ttagaccaaa tatattatta ataacttaat aacatcttaa aacttattta tttatattat
    23941 ttacaacatc catttaataa atacaccata acctacagct gggtcgtttt caattgcatg
    24001 tgacactgct ccgattattt tattatcttg aactattgga gtaccactca taccttgtac
    24061 aataccacca gtttgagcta aaagcttttt atctgtaatt ttaattttaa aacttttact
    24121 ttctggatgt ttttggtttt ctatatctat aatttcaata ttatattttt tacacttatt
    24181 aaagttatct tgtaaaatta tttgagcttt tcctaattta acttcatcta aagatgctac
    24241 tttatatttt tttaacttgg aaatatcaaa gttattaatt tgacctctta ttccaaaatc
    24301 agtattttct gtaaagctac caataatatt ttctcgtttt gcatttatac atccaacact
    24361 acctttataa gatttttcta tattaaggtg cttagttgta gaaattgaac ctgttttaat
    24421 aggtattttt cttgcattac caacacttat tggatgacct acagctccaa actctgatgt
    24481 atctggattg atatacgtta aagtagcaaa tccagaaagt aaattgttaa aactaatttt
    24541 ttctaatatg tgtttggtag ttttcattgt tataagttgt ccacctctat ttaataaaat
    24601 agatacttgt ttttcttctg gtaaagcatt taaggtattg gcaaagtcac tatatccatc
    24661 aacttcagca ttatttacct ttactatagc atcacccaat ctaaatggag atgcttctcc
    24721 aggatttcta actatgatat tttttaattc tgcgtcaatt tgaagtacgt ttccaattgg
    24781 tattaaatat tcaggttcat ttttttgtaa attttgtgca taaattaaat tatttgagaa
    24841 aaaatataat aaaaataaaa atgttaaaac aattgtaaat tttgacttag ctaagttggt
    24901 ttttttactt aaagtattat ttttaaaatg aaaattttta agttgcataa aacacctctt
    24961 tcttattaaa ttattttaat aatagaattg aagttttctt gctgcttcta tattatgttg
    25021 tgcaagaatc atgttttgat gcttggaaaa ctagctcaat aacaccttag ttttcataaa
    25081 aataaataaa ataaatagtg tatatgataa aataaataca tattcatata aataaaaata
    25141 aacaataact gtctagcata agaaaggagc aaaaaatgaa aaaatataga ttgttagtta
    25201 cttgtataat tgccatggga atcataatta taggaacatc aaatccagtt agcaattttt
    25261 acaagactac aaatttgatt agttcaggaa atatcacaaa tgaaaaagca gataaagatg
    25321 aaaattcaaa caaaaataat aaagataaaa atgaagacaa atctaattct aaaagtaata
    25381 aagataagtc atcagaggac aaatcgtcag ataataaaaa tgaaattcaa aaaaataaaa
    25441 aacttttaat ttgtatagac ccagggcatc aaggaaaagg agatagcaat ttagaaccag
    25501 tagctccagg ttcttcctct aaaaaagcga gagtatcttc aggaacagag ggtattgcta
    25561 caaaaaagcc agaatatgtt ttaaacttag aagcatctct tgttttaaag agtatattag
    25621 aatctaaagg ttataatgta ataatgacta gagagacaca tgatgtaaat ataagtaatt
    25681 cagaaagagc aatacttgct aatgacaaaa aagcagatat ggttgtaaga atacatgcag
    25741 atagtttaaa taattcttca aaaactggag catctatatt gattcctgaa aaagatggaa
    25801 aatatacagc tcctatatat gaagaaagta ataaatgtgc tgaatttatc aaacagaata
    25861 tggaacaatc aggtatacaa atcaatggaa tcgttcaaag aggtgatttg actggattca
    25921 actggtcaaa agtaccagct gtattagtag aaatgggatt tatgagtaac tataatgaag
    25981 accaaatgat gtcaaatcca gactaccaaa gaaaaatgat gcagtgtata gctgatggat
    26041 tggatgcgta ttttaaataa gatatgaata gagaaaaagt taggttggta ttatttgcct
    26101 aatttttatc tctatttttt attgtacata acacaaagaa gaagtttatt ttaggttaaa
    26161 ttgtcgtaaa tataactaaa aatattggga atacttgatt taagtttaaa aagaatatat
    26221 tatagtatag aatgtgtaaa atttttttga gaggtgttga aatgctagta gtagaaaatg
    26281 tgagtcatgg atttggtgcg agaacaatat tagaaaatgt atcctttaga cttagaaaag
    26341 gtgaacatat tgcactagtt ggtgctaatg gagaaggaaa atcgagtttt ttaaatataa
    26401 taacaaagaa gcttatgcca gatgctggaa atataaaatg gtcttcaaga gctacagtag
    26461 gttacttaga ccaacatacg gtattaagca agggaaaaac tataagagaa gtgcttagag
    26521 aggcttttaa gcatatgttt gacttagagc aagaaatgat tgctatgtat gacaaaatgg
    26581 gagaagctag tgatgatgaa atgagtaagc ttcttgaaga aacagcagag atacaaacta
    26641 tacttgaaaa tagtggtttt tatatgatag atgcaaagat acaagaagtt gcaaatggtc
    26701 ttggtcttgg agaaattggt cttgataaag atgtaactga cttaagtgga gggcaaagaa
    26761 caaaagtact tcttactaaa cttctacttg aaaatccaac tattcttata ttggatgagc
    26821 ctacaaacta tttagacgaa gagcatataa catggcttac taagtacctt caagagtatg
    26881 agaatagttt tgtcttagtt tctcatgata ttgaatttat aaataataca tgtaatgtaa
    26941 tatatcatat ggaaaatgga gagttaaata gatataaagg aaattatgat gaatttgtaa
    27001 gacttaatga tataaagaaa cgtcaagaag aacaagctta tgataaacaa gttgaagaaa
    27061 gaaaaagact agaggatttt gtagctagaa ataaagctag agtagcaact agaggaatgg
    27121 ctaacagtag gcaaaagcaa cttgataaga tggaaatatt agaaagacca aaagaaaaaa
    27181 taaaacctac ttttgctttt aaagatgcta gagcagctag taaaataatt tttgaaacag
    27241 aaaatttagt tttagggtat gatgaagcat tgacaaaacc acttaatttc catttagaaa
    27301 gaggaaaaaa gattgcctta aaaggaatga atggtattgg aaaatctacc ctattaaaaa
    27361 ctttacttgg aataataaaa ccatttgaag gaaatgttaa attaggtgac tatttggaag
    27421 ttggatattt tgaacaagag agttcaagag aaaatagtaa tacacctatg gatgaagttt
    27481 ggagtgaatt tccagggctt acaaactttg aagttagaca ggctcttgca aaatgtggac
    27541 ttacaaatga acatataacg agtcaaatga gagtattaag tggtggagaa gctgctaagg
    27601 ttagactttg caaagtaatg ttaaaaaata taaatttctt agtattagat gagcctacaa
    27661 atcatttaga tgttgaggca aaagatgaat tgaagaaggc tatcaaagag tttaagggaa
    27721 cagttctttt agtatgtcat gagccagaat tttattcaga aattgttgat gatgtatgga
    27781 atatagaaga ttttacaact aaaatcgtgt agtgatttaa cttattgctg gggggatttc
    27841 atgaaaaagt ttctaaatgt acttttttca atttgtatta gtattgttat aatagtaggt
    27901 gttattaatt ttactgttgg atttaaacaa ctttattatt ttgacattga ttacttaaat
    27961 atatcagagt tatctggttt atctaaagat gatataaaat tgaactacga ttatctaatt
    28021 gattataact taaataagaa tgtgtctgag ttcaaattac caacattaaa atcttctcca
    28081 caagggaaga tacattttga agaagtcagg aatatatttc aaaatataaa taaattagct
    28141 aaattattat tggtagtttc tttagtagga attatattga gtgtaaaaaa taaaaatata
    28201 aaaatcttaa aaactacatc aataacactt ataattatgc cattattatt aacagttcca
    28261 attttattaa attttgaaaa gtcatttatt atttttcata aattattatt tagaaatgat
    28321 tattggatat ttaatcccga tttagaccca gttataaata tattgccaga ggaatttttt
    28381 tttcactctg gaatgatgat tttaatatta attttgttag taagtatagt actgtttgta
    28441 atgtataaat tatgtaaatc tttatcaata aaaatatttc aatgttaaat agagggatat
    28501 ttttatttcc aaaataagat aataaaaaag gattagatta aaagttatac aataaaaata
    28561 gctgtgcaat aatatttaga ctatgaaagt agttgaaaaa tatttatgca cagctattta
    28621 taatagaatt tactttttac tagtgatttt aactaaatct tgaaatttac tcataatgta
    28681 attgtaatta tcttttttat gaggtaatat acaactactg caatctttga tacctttatc
    28741 tgtataccta aagtttccac cacagttttc tcctaaagca tacaaaggac aatagcaaaa
    28801 tagacagtta aactcttctg gtttattagt tttatgacaa gggaaaaatt cgcaatcttt
    28861 gtgattaaaa aacttataat tttcgcccat attttcctcc taattaaata aaatttaaat
    28921 tttttatact atataagatt ttggtgataa tataattata ctaaataatt ttatgaatag
    28981 tcgataatat agtattatta atcatagtat taatggtata attagtcaac agaaaaataa
    29041 tgtaaaaata atgtaagtgt attttgtaat tagaatatgt tttataacaa aaaatgaggt
    29101 gattaagtga aagaaattca agaaaaagca cttcttgtag gtctgaattt gactacaata
    29161 gtgaaaaaaa atgatgatat agacactaat gaatctatgg aagaattaaa agaactaaca
    29221 aaagctgctg gggcagaagt tgtaggtagc ttaattcaaa ataaacactc tgtagatgca
    29281 gcttattata taggaaaagg taaagtagaa gaaataagag cctatagtga ctctttagat
    29341 gctactttag taatttttaa tgatgaatta tctggtgctc aaatcagaaa tatagagaat
    29401 gttgttggaa gaaaagtaat agatagaact actttaattt tagatatatt tgctcaaagg
    29461 gcacttagca aagaaggtaa attacaagtt gaattagcac aattaaaata tagattgcca
    29521 cgactttatg gaatgggtgg tgagatgagt agaacaggtg cagggattgg tactagaggt
    29581 cctggagaac aaaaactaga aatagataag agacatatac ttaataaagc agcagatata
    29641 agacgtgaac ttaaagaagt aaaaaagaat agagagacac agagagttaa gcgtttaaag
    29701 tcaaatatac cgattgtagc acttgttggg tatacaaatg caggaaaatc taccctgttg
    29761 aacgaattaa taaagacaca caaggattat gaacaagaaa aagaagtttt tgtaaaagat
    29821 atgctttttg caactttaga tgtaactttg agaaaggctc ttttgccgaa taaaaaagaa
    29881 tttttagtag tagatactgt tggatttgta agtaaacttc cccatgattt agtagaagcg
    29941 tttaaggcaa cattggaaga agtacagtat gcaaatttaa tcttacatgt aattgatgca
    30001 acaaatacta gttatgaatt gcaaaaaagt acgactgaag gtgtattaaa agaacttggt
    30061 gtaaatgata aaaaacatat acttgtatat aataaagtgg acaagctaga attggatata
    30121 taccctaaaa gtcaagaaga tattgtgtat atttctgcaa aacaaggcat aaatatggat
    30181 aagttattaa atatgataga aattgcttta atggaaaata cttattcagt aagtttgatg
    30241 ttaccttatg agagaggtga tatatttagt agaataaaag ataaatataa tgtggagaat
    30301 tttgagtatg gggaaagtgg tataacgcta gatgcagatt tagatgaaga agattttaat
    30361 atctatagag agtacatact agaaaaatag gttgaatatg gatataaact gggaaaatat
    30421 agataatctt gaagattatt ttataaccta tcttctttat aaagaatcta aaacagtatc
    30481 tcaaattagt aaaattagaa atatttcaag tactgaagca agtgagcaac ttatacaagc
    30541 aaagttaaaa ataaaggaaa tgcaaaaaga tgattttgag gcatctaagg atattttgga
    30601 taaatttcta gaactagata aaattaagag acttgatttt atggatagct tagatgacga
    30661 aaaaatggta tactttaaga gaaaggtttt caaaagaatc cttgtagaaa aaaatgctga
    30721 agatttaatt gttttaattt gggcgacagg tgagctaaaa gatgataggt ttttgaaatt
    30781 gcttcatcag ctcacaaacc acagacactc agatattaga agaataactt attcagcaat
    30841 cagaaagatt gaatcaccaa gtagtagaga agtactgcaa aaaggtctct acgacaaaaa
    30901 tgcacagact aggcagtact gtgcaaaagc tctttcaaaa ttgggagatg aaaacagttt
    30961 aaagatttta cagcagttga aagacaagaa taagaatttt gaaaaagaat atgtgcttag
    31021 agcttatgac gaagccatta agtcattgga aaatgcaaaa aatttgaaaa agtaattttt
    31081 tattaaagca atttgtttac ttaatgatgt atttctaaag tttaacaagg taataaataa
    31141 attaatggga ggggtttcaa atgatagtaa gacgttgtgc aggtggagta gtgttttatg
    31201 ctaataaagt acttattgta aaaaatgata ggggtgaatg gacacttcca aaaggaaaga
    31261 tactaggagg gggacttcca tatgagagtg ctgttcaaag agttaaagta gaaactggca
    31321 tagatgctaa aatgatagat gtggctggcg atactatgta tgaatttttc tcaagaagta
    31381 gacaacaaga agtttgtaat gcaataatgt ggtatgttat ggaagcttgt aacactgatt
    31441 gtgtacttgc tcctgaattt caagaaggtg gattttataa agtaaaggat gctttagaaa
    31501 tgttatcaca tcataaagag caagctttag tagaagtatc ttataaaaag tttaaggaat
    31561 taaagaaatt agtttcagag ggcgatgatg ttccagcaaa ttaattgtga atttagagga
    31621 ttctgaggaa gggatagccc cttccttttt taattgaagc agttttaagc gtaaattata
    31681 tagtctcttt aaactatgat ttatcaattt agagatttag tagtttatat ttaaaatcag
    31741 taagatatat ttaaaataaa aattaaaaag tatacaattt tattatataa ttgtcttatg
    31801 atgttgatta aagaagtatt aaaagtccat ttatttttaa atagaatgat tttataaata
    31861 tatatttgat gtgtatatta gaaaatgatt aaaataggag gaaatacaat gagcaattac
    31921 aggacattac atgaatttgg aacggatgaa ataacgattg aaaagtctgt ttttattgga
    31981 tatgctaagc ctataaagag tgaagaagaa gcattagagt ttataaatga aataaagaaa
    32041 aagcataaag atgcaactca taatgtgtgg gcttatactg taggtaaaaa tatgaatata
    32101 caaagatata gtgatgatgg agaaccacaa ggaacagctg ggatacctac attagaggtt
    32161 ataaaaaaag aagatttgag agatgtagcg gttgttgtta ctaggtattt tggaggaaca
    32221 aaattaggtg caggtggtct agttagagct tatacaaaag gtgctaaact gggacttgaa
    32281 gcaggtaaga taatttataa ggtaatgtat caagaagtta aggttaagat agattatact
    32341 caacttggaa aagtgcaaaa tgagttaatg aatttggggt attttataaa agatactgta
    32401 tatgaggata atgttgaaat agtagtatat tcaagattag aagatgtaga gaaattatca
    32461 gaaaaaatga ttgatataac aagtggaaca ggaaaaatag ttttaggaga ggaattttat
    32521 ttgtctgaac aaaatggaga aattttaata taatctaaaa ggttattaga atagttaata
    32581 cctcaaatag ccaattagta tttttaagtg aaaagccatt aaattgattt aatctaaatc
    32641 aatttaatgg ctttttatcg gattttgcac agaatccttt ttttacttca aataaaccga
    32701 ctaaaagtaa aaatatccca aatatttttt ttaatatatc tgaagacaga taattagcta
    32761 atagtgaacc aaatacagct cctaaaaccc caaacacagc tataggtata accaatttaa
    32821 aaattacatt tttatttttt atatgtatag caagtgctat aagtgtcata gggatagatg
    32881 aaagtaaatt tacgctttgt gctattttag tgtctatgcc agcaagtaaa acgagtgcag
    32941 gtataaggat tgttcctcca cccattccca ttcctccaat aattcctgca aaaaatccaa
    33001 ttagagcaaa taacattaaa acaccatcct taatgctgca attatcataa ttattccaaa
    33061 agaaattcta agaaactttc cagtaacctt atttagtaat ttagctccta taataccacc
    33121 aagaatactt ccaactgcaa ctttaattgt taagttaaca tcataagtac ctttagatac
    33181 atataaaaca gaacttgctg tcgttaagaa tattattata gaaagagcag ttgcatgaga
    33241 tttatgttct tctaccttaa cgatgtcatt taatattgga actaaaagag tacctcctcc
    33301 agaaccaaaa actccattta taaatcctgt aaaaactcca attatcgtat tttttaaatt
    33361 aaaatcaaag tattttttct ttaaatcatc agtttttttc ataaaaatca ccttctgaaa
    33421 tagttttacc aaaataggca aattatattt atataaaata agattaaata taatctttca
    33481 tgtttgttta attttgcata aaaaaaaaca tattaaaaca acatattaat atatggtata
    33541 atatattaaa acaaagtagc aaatttgaga ggagataaca atgtcaaata taaaaataca
    33601 aatagacaaa actgtagaat ggcttataaa taaggttaat gaggcaaatg caaaaggatt
    33661 aattgttggt gtatctggag gaattgattc ggcagtagtt gctaatttaa ttaaaaaggc
    33721 atttccagaa aactctatgg gagttataat gagcataaaa agtaatcctc aagatagaga
    33781 agatgcactt aaggttatag agggatgtga tatagaatac cttgatttag accttataga
    33841 accacaaagt gctatattag acatggtagt aggaaattta aaagataaac atttatatag
    33901 agaagaatat ttaaagatga cagatgcaaa cttaagagca agagtaagaa tgagtacaat
    33961 ttatacaatt gctaacaatc taggatatct ggttgttggt acagacaatg ctgcagaaat
    34021 acacacagga tattttacta aatttggtga tggtggagtt gatattttac ctattgcaaa
    34081 tttaactaaa ggagaggtgt atgaatgggc aaaagagctt ggtgttcatg aagatttaat
    34141 aaacaaagct ccttcagcag gtctttggga aggtcaaaca gatgaagatg aaatgggaac
    34201 tacttacaat atgatagatg ctgtattaga aggtagattg gatgaagttc ctaaaagaga
    34261 ccaagagata attgaaagac ttcatagatt aagtgaacac aagagaaaaa cgcctgcaca
    34321 acctcctaag ttctaattta ctatttataa gatttgtgat aaaatttaca agtgatgaaa
    34381 attagaataa ttaattgtac gtattaagga gtggaaatat gggacgtata ggtaatataa
    34441 ttaatagaaa aggtaaacaa gatgctcaaa gagcaaagat atttactaaa catgctagag
    34501 caatagcagt tgcagctaag gaaggtggag cagacccaga gtacaatgca gcgttaaaaa
    34561 cagctataga aaaagctaag gcagataata tgccaaatga taatatagat agagctatcg
    34621 ctaaaggtgc tggagcaggt gctggagaag actatgaaac tatagtttat gaaggatatg
    34681 gacctggtgg agttgctgtt atagtagaaa ctttaactga caacaaaaac agaactgctg
    34741 gtaacgtaag atactatttt gacaaaaacg gaggaaactt aggaactagt ggatgtgtgt
    34801 ctttcatgtt tgataaaaaa ggacaaatat tagttggttt aggagatgga gtttcagaag
    34861 aagaattgat ggatgttgca ttagaagcag gagctgaaga tttcataaca gaagaagatg
    34921 gttatgaaat aataactaca ccagaagatt tttctagtgt tcgtgatgag ttaaaagcta
    34981 aaggatatga gtttatatct gctgatgtga agatgatacc tcaaactaca actgtattga
    35041 ctgaagaatc tcatttaaaa atgatgaata aattagttga tatgcttgaa gaagatgatg
    35101 atgttcaaga tatatatcat aactgggaag tagaataaat agtataagca tattgaaatt
    35161 tataagtatt gaatcaattt taacatgtga taaattttat agaataagaa acactaaaat
    35221 agacatacgc acctctaacc tatatttgca taataatatg taagcatagg taaggggtgt
    35281 ttttatattt ataggttaag aaatttaaag taaattttga gctggactcg attgtctata
    35341 aataattgat gggtatataa cttgttgctg aataccattt atacgcccag ttactgtatc
    35401 aataatcatc ctaagactac gttctgctgt ctcttccatt tttaaatcta taactgtcaa
    35461 aggaggaata cttcttgcca ttagtcgtga aggtccatta cttgctgcaa atatttgaat
    35521 atcctctcca attacaattc ccgattcatg aaatgcattc atcataccaa gagctaccac
    35581 atcatgatta caaaaaatta ctttttttag tgaatttttt gcaagcattt tttgagcaat
    35641 atcatatcca ctatctattt tattagaaca ataatatata gaatctgata gatgtattcc
    35701 atgttcttta catgttttta aaaaagattt accccttaaa gtcatacatg taaaggaagt
    35761 tgggttgaat acaacagcaa tatcattttt accattttga atagcatgta aagctgctat
    35821 acgaccagtt tcctcattat caatagatac acttgaaaaa ccaggtattt cacgatttac
    35881 aacaactaca ggaattttag gtttattttt tactagatat tctatatcat cagcattgat
    35941 acctgttaaa acaattccat cataataatt atttgcaaaa aagtattcat catcacatag
    36001 atgaccaact ttgtaaggtc gtatgatgat atttatgttt aaatgttcta aagaaattat
    36061 gtggtttatt gcttgaagta tattggttga tgccaactca aatccctcat cctgccaata
    36121 aaaagctatt ttaatattat tatgtttaat aggagtagag cgtttatatc caagcttatc
    36181 agctgaattt aatataagct cttgtgtatg tagcggaatc ctgcgttcat ttcctttacc
    36241 acttaagacg tacgagacag ttgctgaaga aagaccacag tcttttgcaa tatctttgat
    36301 tgttgccatg ataaaatcct ccttaaatag ttgcttaaat ttgcttatac caataatctt
    36361 aacatatatt caactaaaga acaatattct acaaggtgca tattttacag gattagaata
    36421 aataaattaa aaaaaacttc ttacttatgt tgacataatt tagtttatag gattataata
    36481 tgcttaaata agcttatgat taacttgaat taagcaaagt taagcaggaa catgcaatgc
    36541 tagcttgcaa tgtgactgca aagggggaaa aggtatgagt aaggtaaata tatttgaagt
    36601 tggtcctaga gatggatttc aaaacctgaa agagttttta gaaactgata aaaagcttaa
    36661 gattattgat ggtcttattg cttctgggat taaacaactt gaaattagtt catttgtaag
    36721 cccaaaagca atacctcaga tgaaagatgc aaaagaagta gcaacttatt gtgtagaaaa
    36781 atatcctgat gtgaaacttt atgcattagt tccaaattta tatggtgcta aagttgcatg
    36841 ggagtgtggt ataagagata tatcctatgt tatatctttg agtgaaactc ataataaaaa
    36901 aaatataaat cgtacccatg aagagtctat tgatgagctt aaaaaaataa tgaatactta
    36961 tccagacatg aatatatgta ttggaatggc tactgtattt ggatgtcctt ttgaaggttt
    37021 accaaaaatt gaagatgcca taagatttgc taaacgcctt tgggaaaacg gtatcaggga
    37081 gataaatcta gcagatacaa tagggattgc tgaccctaag caagtaagag aaactattag
    37141 tgcattagtt gaagctttac cagaatgcag atggcaagta catattcatg atactagaaa
    37201 tatgggaatg gttaatactc ttgtggctat tgaatctgga attactactg ttcagtctac
    37261 acttggagga ttaggaggat gcccatttgc tcctggagca tctggcaata ctgcaactga
    37321 agatttagta tatatgcttg aacgtatggg gtatgataca ggagttgatt ttgttaaact
    37381 tcttgaatta tcaaagtatc agaagagttt tgtaaatgga gtatatagtg gtcatcatgt
    37441 aaatataaag tctgatagtt gtaattgtta gttctattga ttaatcgatt aaaaaaatat
    37501 gttgattaaa aaaatatgct gattggtaaa atagatttat tgataaaaaa tataaattat
    37561 aaaatacatt atctaataaa acaaataaaa aaattgaggg ggattagtat ggatattata
    37621 gctttacttt tatttttagg agttattatt attgcatttg tacgtaagaa taatgcaggt
    37681 attttggctc tagctattgg tgtcatagct gttagaattt ttggaatgga tgataaagaa
    37741 ctttatggag ctataagcaa ctcaatgttt actacacttg ttggtataac actactcttt
    37801 gcaatagtga actcaacagg agcattaaag cttgttgcag aaaaaattgt agctgcttct
    37861 ggtaaacgtg tttggcttat acctatagca gtttttatag caggatttgt tgttgctggt
    37921 gttggacctg gggcaattcc agcacttgca attatcccag caatggctgt tcctgtagcc
    37981 ataacggttg gttataatcc tgtaatgctt gcacttatag gtgaatgtgg attaatggca
    38041 ggtcgtatga ctcctattac tccagaaggt caaattataa caaccgttgc agaaggggtt
    38101 ggaattgaaa atgttatgcc tactatctta gcctgtcaaa ctctttctac aattgtattt
    38161 tcaatagtat tgtttataat tttcaaagga tataaactta aaaaacctat aaatgttata
    38221 gatagtaagc aaatagaaaa attcaatata aagcagataa tttctctaat aagcatagta
    38281 gttatgattg cttttatcat aatttttgat atgaatgttg ggcttgcagc ttttgcagtt
    38341 tcagctgtac ttattttttt caatattgct gatgaaggag aatgtatcaa atcaattcca
    38401 tggagcacga tagtaatggt tcttggagta ggtgcaatga tgacaatcgt agatgcagca
    38461 ggaggtattg acttgatgag taatgcatta tcatcactga tgaatagtaa aacagctact
    38521 ccaattatga gtatttcagc aggacttatg tctatggtta gttctgcttt agcagtagtt
    38581 tatccaacta tgatgcctat gtgtgttgat atagctaagg cagttggagg agtagatcca
    38641 ctagcactta ttgctgcagt tggtgttgga ggttctcttg ctggtgtaag cccactttct
    38701 actggtgggg cattgatttt agcagctatg ggttcaagta agaaagactt taataaggaa
    38761 gaacaaaata aggtttttgt acagcttttc attatgagtg cagttggctt attggttatt
    38821 gcagtagtat caatattatc atttaatgca ataacacatt taatgaacta attagaataa
    38881 ctgaaaataa atcattaaat ttaactttta atattaatca atataatata atttggaggg
    38941 gaagttatga aaaaaggagc attaagcaat ataaaggtac ttgaccttac aagagttctt
    39001 gcaggtccat attgtacaat gatgttggcg gattttggag ctgatgttat aaaaatagag
    39061 atgccaagaa aaggtgatga tacaagaggt tttggacctt ttgtaaatgg agagagttta
    39121 tactatgcaa atataaatag aaataaaaaa ggtatcactc taaaccttaa atcagaagaa
    39181 ggaaaaaata tatttttaga aatggtaaaa catgctgatg ttgtagtaga aaattacaga
    39241 ccaggtgtaa tggaaaagtt aggtctgggt tatgatgagt tggctaaagt taacaatcaa
    39301 ataatttatg gagctgtatc aggatttgga tgttatggac catattcaga acgtccaggt
    39361 tatgatatta ttgcacaggc aatgggtggt cttatgagta taacagggca agaaggagga
    39421 gaaccaacga gagttggtaa tgctatgggt gatgtactag gtggaatgaa tttaactatt
    39481 ggtatactca cagcactcaa cgctagaaaa ataataggaa aaggacaaag agtagatgtt
    39541 tccctcgttg attctgttgt atcgtctctc gaaactggta tacagagata ctttgattca
    39601 ggacaacctg aacttatggg taatagatat gcttcagcct atccttatga ctcttttaag
    39661 gcaagtgatg gaagttttgt aataggctgt ggtaatgaca aactttttga aaagttatgt
    39721 aaaaaagttc tttttagaga agacctttta atagatgaga gatttaaaac aaatcttaat
    39781 cgttgtgaac attacaaggc tcttaaacca gaaatagaaa aatggtctgt taagcataca
    39841 ataaaagaag cagttgactt aatatcagag gctggagttc ctgctgctcc tatctataat
    39901 cttgattgtg ttacaacaga tgaacatata gcaaaagcaa gagaaatgat tgtagatatt
    39961 agtcatccta ttataggaaa tatgaaagtc aatggaaatc cagttaagtt gatgacaaca
    40021 aaagctaaaa ttgatatgcc agcaccatct ctaggggaaa gtaacgagga gatttataat
    40081 ggttggcttg gttttgatag tgataaaata aaagatttaa aagaaaatgg agttatttga
    40141 ttaaaaaata gctaaacaca cttgtgactt tagtcatggg aggttcagtt agaataatat
    40201 caaaaaatat taaatcaata ctgtaaataa aatatagaat tgtcagaagc atttaagatg
    40261 ggaaaagcta cttagacatt gagtctttgt ggcttttcct attttcatta agaattttat
    40321 attatcagaa tagatatgta ctaaactaaa gtattaacaa tttaaattaa tagaaaataa
    40381 actacctaat tatgttgaat aaagactact ttagtgaaaa caaacttata gagatgctat
    40441 ttaaattatt ttaatgggaa tatcaaaaat gagactgcat tctcaaaaat gagactgcgt
    40501 tttttaagta ttttctcgaa aatgagacaa aaatattatt ttatgggttt tattgaagaa
    40561 aaattcttct gtgaattaca atttaatcaa ttttaaagtt gaaaattgtt aaaaatttag
    40621 tgaaatttat gtatatttcg tttattttat taaaaataac aattttttac taaaaataaa
    40681 gaacttcaat ggtgattggc atagtacttg ctattttata ttaacaagaa atgtagaaaa
    40741 aataacaatg tataatgggg ggaatatgat ggaatctgta atggaaaatt tgaacaatct
    40801 taaggtggag gttaaggaca aagtctgtgt tattactata aatagaccta aagctttaaa
    40861 tgctcttaat agtgacactc ttagggaact atcacaagtt attgatgtag tatcagaaaa
    40921 tgaggcaata ttaggagtta ttattactgg agaaggtaaa gtttttgtag ccggtgctga
    40981 tatacgccag atgcaaaact ataaaagtga ggaaggcaga aaatatgcag gttatgctca
    41041 gggaattttt gataaaattg aagctcttga gaaaacagta atagcagcag ttaatggata
    41101 tgcattaggt ggtggatgtg aacttgctat gagttgtgat attagaattg catcagaaaa
    41161 ggctatattt ggacaacctg aagttaattt aggagttatt ccatgttttg gtggaactca
    41221 aagattatca agacttgttg gaactggaat agctaaagag ttaattttta cggggagaca
    41281 agtaaatgca gaagaagcta aatctattgg gcttattaat aaagtggttc caagtgattt
    41341 acttttagaa gagtctatga agatgatgaa ccaaatagtt gaaaaagcgc caatagcaat
    41401 aagatatgca aaagttgtta ttaacaaagg gatagatatg gatttaaaga atgctcttga
    41461 actagagaaa gatattgcag gtttaacttt tgctacaaga gataagcaag aaggaatgaa
    41521 tgcatttata gaaaagagaa agccagtttt tgaaaataag tagctattat aactaaaatt
    41581 ggaacaatgt agaatatatt caaaatctaa atttcgtgaa aaaatacata tagtttaatt
    41641 ttaaaaggag ttaatttatg aatacgggag taattataag tttagtaggg attatcatag
    41701 ctctatctct tctagttgta atggttatga agggaataaa tatttttatt atagcaattg
    41761 tatgttcatc attagttgct ataacaggaa gcctaaatgt gtatgatgca cttaaagtgg
    41821 attatatgac agggtttgtt ggatttcttc aggcaaattt ctttattttc ctaacaggta
    41881 cattaatggg aaaaataatg gagattactg gtggagcaaa atctattgct aagatgattg
    41941 taagatggat tgggaaggat aaagcactac tttctattcc aatagcttgt ggaatattag
    42001 cctatggtgg agtaagtgtt ttcgttgtaa gttttgcagt gtttccgata gctttagaaa
    42061 tttttaaaga agctgatttg ccacgaagat ttataccagc agctttgact tttggatgct
    42121 caacttttgc tatggttgca ccaggggcac cacaaattca gaatattgtt ccagcatcaa
    42181 cattagggac agatattatg gctggagcag taaatggttt tatatcatgt gcagtaatgt
    42241 ttatagttgg aagtacaatt ttgtacaaaa tggtttcaaa agaaaaagcc aatggtggtc
    42301 attttatagc acatgaatca gatatatttg atgaagcaga agcaactaat tctaagagag
    42361 aaaatggtcc caatggtgta attgccttaa ttccattgat agtgtcaatt ttaataatta
    42421 atgtaaaagt taatggaaaa gcgatagtac caattgaggt gggagtattt attggagctt
    42481 tattagtata tttattgtta aataaatatc aagataatgc taaaatagtt ggacatgttg
    42541 gtgatgcatg taaaactaca gtagtagcaa tatgtaatac ttgtgctgta gttgcatttg
    42601 gttcagtagt aaaatcagca gttggttttg acttcatagt taatgctatg actaatattc
    42661 ctggtcctcc tattgcaggg gctgcagttg gaactacagt tattgcaggt atttgtgggt
    42721 cagcttcagg tggactagga attgcagctc cacttcttgg accagtattt ttagccaagg
    42781 gtgtttccgc tgcagcatta actaggacta tggcaatttc atcagcagca ttagattcac
    42841 ttccacacaa tggatatatt gttactgtaa caaatggtct ttgtaaagaa acacataagg
    42901 atgcctatat gccaatattc tgggtaactg ttttaacccc atttattgga accatagtag
    42961 cagtcctact gtttacaatg ttcccgggat tgccataaga gaaaagataa aaggtataaa
    43021 ttatattttg atgttataaa atcaattttc aaaatatata caataaattt catgttttaa
    43081 tactgtaaat atgtatttaa aataacaaat tgaccatata aggaggaatt gaaagtgtta
    43141 aataaaccat tagagggagt taaggttatt gacctaacgt attttgtagc aggtccaggg
    43201 acttctaaaa tattagctga ctggggtgct gacgttatta aggtagagcc aagctttgga
    43261 gacccaggaa gaaagacagg ggcaacaatg acaatgccaa tagatgatta taataatcct
    43321 ttttacagca catataattc aaataaaaga ggtttgtcta taaatcttaa gagtgaaact
    43381 ggaattgaaa ttatggataa gcttttaagc gaagcaaacg tatttgtttc aagttataga
    43441 acaggagcat taaaaagact aggtcttgat tatgaatcat taagtaaaaa gcatccacac
    43501 cttatctggg gtcagataaa tggttttggc gattttggac ctgctaagga taatgcagga
    43561 tttgatacag ttgccttttg ggcaagaagt ggggctatgc ttgatatagc agaaaaagat
    43621 acaagtccaa taaatccacc tatagccttt ggagatgcaa caacttcttg tagtttatct
    43681 ggaggaatat gtgcagcttt gtaccagcaa gctaagactg gaaaaggaca aaaagtaatg
    43741 gcatctttat ttgggcaagc aatatggaat gcatcatctt tattagcatc tacacagttt
    43801 agtgatgagt atccaaaaac tagaaaaaat gctatttcac cagtaataaa ttcttatcgt
    43861 tgtaaggatg gaaagtggat attcttaagt attttagagc atgaaagata ttttgaggca
    43921 ctttgtagat tatttggaag agaagactta ataaaagaag agaaatttgc atcttcagta
    43981 gaaagtaaga aaaatgccac agaacttatt agtattttgg atggtgaatt tgcaaagttt
    44041 actcaaaatg agatggttga aaaacttact gctgctgata tagctcatga aaaaattcaa
    44101 catgttaatg atgtagtgac tgatgaacag gctattgcta ataactatat atatgaacat
    44161 acaagtaaaa atggaaataa gacaatgctt gcatctactc cagttaaatt tggaaatatt
    44221 gaagttaaca tgacttgtga tgctccactt ataggagaac attcagatga gatattgaga
    44281 gaacttggat acagtgattc tgatatagag gctctaattg aatctggaat tgtaacaatg
    44341 aataaagaag catgtgaaat atgttaataa acatgtgaag tatgttaata aataggaggg
    44401 aattttatgg attttagatt aacagaagca caattaatgc ttcaaagagt agcaaaagaa
    44461 tttgcagaga atgaaatagc accaatagct gctgaaacag ataaaacagg tatttttcca
    44521 agggagcttt ttagcaaaat ggctaaaata ggatttaatg gaattggaac acctgtagag
    44581 tatagtggtt ctggtggggc agatatagaa aaggtaattg ttgttactga gattgccaaa
    44641 aaatgtgcag catctgcagc aatattatca atacacacaa tatatgctca agctattttg
    44701 aaatttggta ctgaggaaca aaagaaaaaa taccttccaa tgatggctga aggtgggtgt
    44761 gtaggtgctt ttgccttaac cgaacctaat gctggttcag atgctgcaag agctgcaaca
    44821 actgcaatta ttgatgaaga aactgatgaa tatgttttaa atggaactaa gtgttttatt
    44881 tctggtggag gtcaagcaga atcattaata atatttgcat tgacagaccc atcaaaggga
    44941 ataaagggaa tgtctgctat cattgtcgac aaaggtactc caggtttttc aataggaaaa
    45001 attgaagaaa aaatgggtat tcatggttca gaaactgcag agttaatatt tgataactgt
    45061 agagttccaa agtctaactt attaggaaaa gaaggcaaag gatttaatat agctatgact
    45121 tgtttagatg gagcaagaat tggagttgga gctcaagctg taggaattgc tgaaggggct
    45181 ttagaagaaa gtatcaaata ttctaaagaa agagtccagt ttggcaagcc aatttcagct
    45241 ttgcaaggta ttcaatggta tatagcagat atggcgacaa tggtggaatc agcaaaatta
    45301 ttagtatatt atgctgcaga tttgaaagct agaggagaaa aacacactaa agaagctgct
    45361 atggcaaaat acaatgcgtc acgtactgca agagaggtta caaatttagc ccttcaaatc
    45421 catggtggat atggatatat gaaggattat ccattagaga gaatgtacag agatgccaaa
    45481 ataacagaaa tttacgaagg tacttcagaa atacacaaag ttgttatttc aagagcagta
    45541 ctaggatagg aggaaaagaa tgaatatagt tgtttgctta aagcaagttc cagatactaa
    45601 tgaagttaaa ataaataaag agacaggtac tctaataaga gatggtgtac caagtataat
    45661 caatccagat gatagaaatg ctttagaaga agctctaaaa atgaaagatg aactaggagc
    45721 agtgattaag gttataagca tgggacctcc tcaagctaaa agtgctttaa aagaagcttt
    45781 ggcaatggga gctgatgaag cttatttaat ctcagataga gcttttggtg gttcagatac
    45841 ttgggctaca tctacaatta ttgctgctgc tatagagaag gttggaaagt atgatgtaat
    45901 attctgcgga agacaagcta tagatggaga tacagctcag gttggaccag aggttgcaga
    45961 atttttaggg ataccacaag ttacttatgc gaaagaagta aaggttcaag atgacaaatt
    46021 actagtaact cgttatacag agacagggga ttatttaata gaagcaaaga tgccagtttt
    46081 attaactgct ataaaagagt taaacaatcc aagatatcca agtgtcaaag gaatcttaga
    46141 agcttataat aatggagatg caaagattac tgtattaaca cttgcagatt tagatgttga
    46201 tacaactcaa attggattaa agggttcacc tacaaacgtt tataagtctt ttgtaccagt
    46261 taaagacaag cataatgaaa taatagaagg tataaataaa aaagaaaaag ctgagaaact
    46321 aatagaaata ctattcgatt tgaaactagt ataggagtgt taagatgatg agagcaaaag
    46381 ttaatcaagg tataaattta aatgattata atggtgtttg ggtaatagga gagcaaaggg
    46441 aaggtaaaat taatcctgtt acgatagaac ttattggtga aggaagaaag cttgctgacc
    46501 aattaggaaa agagcttgca gttgtgatag ctggatatga agtagagaaa gaagtgaaag
    46561 aattacttca ctatagtgtt gataaagtat attacatcaa tgaccctctt cttaaagatt
    46621 tcactactga tggatatgca atttcaattg caaatttaat cgaaagaaaa aagccagagg
    46681 ttgtattggt tggtgctact tctataggaa gagatatagc gcctagaatt gcaggtaagg
    46741 ttggaacagg tctaactgct gactgtacaa aacttgaaat agattcaaca gataataagt
    46801 tattacaaac aagaccagca tttggtggaa atttaatggc cactattgtt tgtccaaaaa
    46861 atagaccaca gatgtcaaca gttcgtccag gagttatggc aaaagctgta agaaacgaat
    46921 cagagactgg aattttagaa gttgttactc cagaacttac tgaaaaaatg attagaacta
    46981 gattagtaga gatacttcca caagaaaaga aatctgtaaa tctaactgat gctagaataa
    47041 tagtatcagg gggaagagga ttaaaaagag cagaaggatt tgagcttata aaagaattgg
    47101 ctgataaatt gggggcagag attggtgctt caagagcagc agtagattca gggtggatag
    47161 aacattctca tcaagtggga caaacaggaa ctactgttag accagaacta tacattgcat
    47221 gtggaatatc tggagcaata caacatttag caggtatgag tgattctaaa tatatagttg
    47281 ctataaataa agatgcaaaa gcccctattt ttagtatatg tgactatgga atagtaggag
    47341 atttatatga aattatacct gaaatgatag aatcattaaa taggtaactt ttagaaaaca
    47401 ttgaatatgt agaatgataa gtcttataat attgtattgt aagacttatt atttttgctg
    47461 aaggttatag tggggagatg aaacaatgaa agagcagtgg tataaggata tatttgcaag
    47521 agtattatct atgactgatg atggttttat tgttgtaaat acaagtggag taataataga
    47581 tattaatgat aaatattgtg actttttagg aaaagaaaga aaagatataa taggacaaaa
    47641 tatacaaagt attataccaa atacaaaaat gctagatgtt atgaaaaata agtattgtga
    47701 agaaggagct atacatcatt attcaggtgg aaatacaaaa gaaaaaagtg taatagtaag
    47761 taggtcttat gtggaaaatg acaatggaga agtagttgca ggagtagctc aagttaaatt
    47821 tagattgcaa tcatttgatg tagctaaaaa gctaatgtca gaatatatgg agctccaata
    47881 ttataaagag cagtttaagg ataactgtgg ttttgacaag ctcataggtg aaaatagaga
    47941 cttcatagaa cttaagaaaa caggtgtgaa agcttctaaa acaaactttc cagtactttt
    48001 aacgggtgaa acaggtacag gaaaagaagt ctttgctaga gcaattcaca ataatagcag
    48061 caggtcagat aaacctatgg ttagtataaa ctgcgctgca ataccagaag aattattaga
    48121 gtcagagcta tttggttatg acgaaggagc ttttacagga gcaaaaaagg gtggtaaaaa
    48181 aggtaagttt ttagttgcaa ataatggtac aatcttttta gacgagatag gtgacatgcc
    48241 tttgaccatg caagcaaaac ttttaagagt tcttcaggaa agtgagatag aaccagtggg
    48301 aggtcttaaa actataaaga tagatgtaag agtaatctct gccacaagaa agaatttaag
    48361 taaaatggtt gaagagggat tatttagaga agacctatac tatagattaa atgtaataaa
    48421 cattcatatg atggaattga aggacaggca agatgatatt ttattgctag caaattatat
    48481 attaaacaaa ttaaatgttg aatacaagga attgaaggtt ttaagtgata aggttaaaaa
    48541 ttgttttatt aactatactt ggccgggaaa tataagagaa ctacaaaatg taataaaaag
    48601 tgcctatgct gtaagtgatg atatggtcat tatgatgtgt gaccttccat ctaagatgga
    48661 taatatcagc agagtagctc aatgtaatgt ggatagcaat tgttcaattc atgaaatggt
    48721 tgagaattat gaaaagagct taattattga tgtgttaagg aagtataatt ggaaatgttc
    48781 taaggcagca gaggttatgg gaatacacaa gagtctttta tataagaaaa taaaaaagta
    48841 tgaaattgaa ttaaataatt aagataaatt gaattaaggc aatgctaaaa aaacgccctt
    48901 attcaaagcg aactgtataa actgttttat gcagttaaaa cgtgtaaaag tagatgtgaa
    48961 gtactaatgt caatcattag tactttttta ttatatttat aattactatc tatatttcag
    49021 tatcttttga tatctaagat tattatgttt aatttaggat ataacaaaac cctcttagtt
    49081 atggacagtt ttttatattt taactgtcta ctaagagggg atagtttagt ttaaatttag
    49141 agtaaatttt atctagcatt tataaaaaat attttgaata gcttttttgt tatttaatca
    49201 taattttcta cttctttatc aagttctttg ccacaagaat cacacttata tatagcattg
    49261 tatccgtaat catattcatc aactattttc ttttgtctaa atacaccacc acactcacat
    49321 aggaaaccaa tttttataag tgtaacgata aattgtgatt ttataaattt tatatcatta
    49381 catttatcgt tagtgtaaaa tgtataaata taagagttat cgcactcatc tcttaattca
    49441 aatctttcaa tatatgtgtt attttttaat tcctcaaatt cttctttagt taaatatgat
    49501 ttttgttgca attcatgtaa acgcttaatt tggtccatta tttatatcct cccaataatt
    49561 ttagtatttt aagcttagat aaggaatcta agttttatta aatttatccc aaggaattat
    49621 ttaaatcata tttagtttta ttaattacaa catatataaa ttacacgaaa ataaaactaa
    49681 ttgtaaaaat aatatcctgt gaaaacctaa actactaacc ccttactaac ccgaaaacta
    49741 aaaaaagaaa atatatccaa atataagtga tatataaata aagatgtttc atataaattt
    49801 aactttaaat attctgacaa taatatatat aaatatatta tagttaaaat ataccacata
    49861 ttttgggtat tgtatactgg aattagagta attaatttat tttttaacat acaaatgatt
    49921 ttatgaaaaa aaacaagact caaaaatttt tatattcttt gatagaataa aattgagagt
    49981 aaatttattg aattttataa aatttataag gggtgagtct aagatatgca tgaagataaa
    50041 aatgatatat ttgaatcaat agatactgag gattttgata ataaaacaga agaagaatgt
    50101 ttagagctag taagaaaaaa tggattgaat ttaatataca taaaaaatca aacagaagag
    50161 atatgtctag aggctgttag acaaaattgt aatgcaataa aatgtgttca gaatcagaca
    50221 gaaaaaatat gtatagaagc agttaaacaa gattggagaa tgttagaatt tgtggaagag
    50281 ccaacagaag aaatttgcat gttggctatt aaccaagatg gaacagcctt aaaatatata
    50341 gaaaatcaga cagaggagtt atgcttaaga gccattgaaa aaaatggtgc ggctttggag
    50401 tatgtaaaag aacaaacaga agaaatatgt atagaagcag ttagaaacag cgaatttgga
    50461 ttggcaagag tgaaaaatca aacagaaaaa atatgtatgg aagcagttaa gcattgtagc
    50521 tataatctaa aatgggtaga aaatcaaaca gaagaaatat gtatggaagc agtgagacaa
    50581 aatgggcttg atttgaaatt tgtaaaaaat caaacagaaa caatctgttt aagagcagtg
    50641 agacaaaatg gaatggcatt agaatttgta aaggaacaga ctgttggtat atgcttaaag
    50701 gcagtaagac aatatggaat ggcattaaaa tttgtaaaag aacaaacaga agaaatttgt
    50761 acagaagcta taaaacaaga taaaagagca cttagttttg taaaaggaga taaggaaaaa
    50821 tacaaggctc tatatgataa taatgaacca tttgcaaaga gatatgttag aaatgtaata
    50881 gaaaaagaaa acagagcatt gattaaaaaa ggagaagaaa atgcaaaaat caaaattgca
    50941 ggaaaacttt atgatagagg catgtctttt gaagatatat cagatatagt tgagattgaa
    51001 ataagcaagt taaaagtgag tttaggtgtt ttttaaagta ataaatgtag gtgtttttta
    51061 tgggaaatag ttaataaaaa aataatcgac tagctctttg taggacagca aaattagtga
    51121 tataatttga tgtataataa attattttta ttagataagg gggaattaaa gttgaagatt
    51181 acagtattat accaaacaag aagtggaaac acagaaaggg tcgctaagct gatagaagat
    51241 ggagctaaaa aggtggatgg agtagatgta aagcttatga gacttgataa tattgattta
    51301 gattatttaa atgagagtaa agcagtaata tttggaacac ctacttattt agcaaataca
    51361 acttgggaag taaaaaaatg gtttgatgaa gattcaaaaa aagttaattt agctggaaaa
    51421 ttaggagctg tttttgctac atgtgattat atatgtggag gtccagatgt tgcgatactt
    51481 actatagtag gacatttgat ggttaaagga atgcttgtgt attctggagg tggttcttta
    51541 ggaaagccat ttatacattt aggacatgta cattcaattg aaggtccaga gttacaagat
    51601 gagaaggcta taatatttgg tgaaagaatt gctactaagg caaaagaact atttgcttaa
    51661 tttctatatg cataataatg attagagtaa atttagggtt ttaagggaga tttgaagtaa
    51721 aagttataaa ataaaaaatt ttccataaaa ttactcaaga tgaattataa tataattata
    51781 aataaattat attattaaaa tatttaaaat caaacgtcaa tagcgaggga agtttatggt
    51841 atggcatata gaatatgaga ttttttctgc aattatagtt atttttttaa tggtatactt
    51901 ttttagaagt aaatttatac ctactttaca aaacaaaata tattgtgcac ttttaatatt
    51961 ctcattttta tttataattt caaatatttt aggttcattt tgtctaaata atatagacaa
    52021 aattccaatt tttattactt ttttattgaa tcagatatac ttattgttat tgccaatacc
    52081 agcagcactt gtatcatttt atgttatggc tattatttat caagatataa ggtatatgaa
    52141 aaaaagatta ttatttttat ctataccact tataatttgt ataatcttat ctattacaaa
    52201 tccttttacg catattctat ttggattgtc aaaagaaaca ggttatatac gaggttgtgg
    52261 atatgttgca acttttgcat cttttttctt ttatgcaata tattcagcat ttttatcttt
    52321 taaatataga aaagcaatgc atgaatcaaa aatatgggct attagaggtt ttcttatagt
    52381 ttcaattgtg gcaattatct tacaggcaat ttttttacag tatcttctta caggaactgc
    52441 atgtgcatgt agtttacttt tgacatatct ttctatgcag aatcgaggtc ttattattga
    52501 tgaccttact ggtgtactca atagacaatc ttttattcaa gagctagatt tgaatatcaa
    52561 tactgaacaa tcaggattta ttattacaat tgcgcttgat gattttaagt ttatgaatga
    52621 aacttttgga acaaaaaatg gagatattgc actaaaagaa gttggaaaat atttgattca
    52681 gatacatgat gtaaaccatg tatatagaat agggggagat atattttcta ttgttgtcaa
    52741 tagtcaatta ggtatagaac cagatgatat tatcagaaag atagaagaaa gatttaaaaa
    52801 gccttggcta gtagaagaga taagttttaa tttagcaact agtattgctg ttgtttatta
    52861 cccagaaaat gcagaaacga cagaagatgt aattgttgct atagatttct ctatacatga
    52921 agcaaaacgt tctgagtcaa ggcgagttgt ttatgcagat gcgtctataa gtgaaaagat
    52981 aaagaagaaa catgttatta aaaattgttt aaaagaagca ttaaaaaatg atgggtttga
    53041 agtgtactac caacctatat tttctaatag caggggcagg tttacttcag cagaggcatt
    53101 acttaggcta gaacacaaag agttaggttt tatacctcct gatgaattta ttccaattgc
    53161 agaacaaaca ggattgatta actcaattgg attagtagtc tttgagaagg tatgtagatt
    53221 tatagctagt gatgagtttg aaaatttaaa attggataat atagctgtga atctttctgt
    53281 agtacaatgt atgcaaaaaa acttagctga tgatttactt tatcttatga ataaatataa
    53341 tgtatcacca actaaattta aacttgaaat tactgagact gtggctatgg gctcttttaa
    53401 tataattaaa gaaacaatgg aaagattaat tgatttaggt gttaagtttg cacttgatga
    53461 ttttggaatt gcttattctg gagttactaa tatgctttct ttaccatttt cagtaattaa
    53521 gttagataag agtttgattt ggtctatgaa tgaagatagt aggcataaac ttacagttga
    53581 gacgattata gctcttataa ataaattgaa tatgaaggct gtagcagaag gtgttgaaac
    53641 cattaagtgt gctgaagatt taatagctat ggagtgtgaa tatttgcaag ggtattattt
    53701 ttctaaacca gttccagaag atgtttttaa aaatttgttg aaagaaaata cttttacaag
    53761 ttaacaccct ttattttttt aattacaact ttgttcattg acactgccag cgatatatta
    53821 taaaattaac acaataataa atattaaatt tattatacat attattaata ttaattaatg
    53881 gagtaaagat ttattatata ttttatttaa ttatcctaaa gtgagaaagg aagatgtgac
    53941 atgaataaaa agaaaatatt agtgccaatt gatgggacag aaagaagtat gcattctttg
    54001 gaatttataa aaggaatatt taaaaaagat gaagttgaag tagaaataat gaatgtaaaa
    54061 gaactagtat ttattgatgg catatccctg gctgaagaga taaaaaattc tgaaaattta
    54121 ggaagaagaa tcttggataa agcagcagag ataatgggag agtatgatgt taaagtacat
    54181 tttacttttg gatatccagg agatgagata attagaaaag caaaagaaga taatgtagat
    54241 tttatagtta tgacaaaatc tactaaaaaa ggtcttacaa gaatgatagg ttcagtaaca
    54301 gcaagtgtag ttaaacaagc aaaatgtata gtgatgattg taccggagta gaattagaaa
    54361 ggtatttgaa atatgaataa aaagatagta gcagtttgtg aaagtgaaag aagtttaaat
    54421 tctcttaaga cagctgcaaa tgatttagga tttgatttag tttatgaaat tcaagaaaat
    54481 gataatataa aaaatgaact ttctatttat gatatagaag atgcatccat agtgttattt
    54541 gttacaagtg attctataga aagcatagag aagattgata gatttataga tagagaattt
    54601 tatgaagttg atccaaagta tataatagag gatgcaaaat ctatagtaag tgaaatttta
    54661 atagacttaa attaatcgtg ggtgtcgcac taagaataga gcgacgcctt tttatatatt
    54721 ttacacaaga aataaagagg ttgtatcaaa atatagataa gactcttttt cattgttgaa
    54781 atgatgaaaa tatatttgat ttcatacaaa aaagagtacc tcataactaa aaagttcact
    54841 ttgagacact ccatttttat atgttagttg catttaaggt aaaatataag tttaatcatg
    54901 ttgaaataac tgaattacat cttctaaatg attgtacatt gatgtataac ctaagtaaga
    54961 gtctttacta tcaaatgcca tcattatctt gttatggtgg ctaatcatat ccttgagaga
    55021 atttctatat ttaaaaccga agtattggtt agaagaaact gttttaggta ttaactcata
    55081 atattttata aaaattggat tatgagaagc taaaattatc tctttgtgaa attgcaagtc
    55141 agcatcataa cattcttcta tcaaaccatg agaaacctta tccaattcct ctattgactt
    55201 taggtaagta tattttattt tttgaagttc tttagatgta gcatttaaaa ttgctagttt
    55261 agtagcttca ctttcgataa gttgtcttgc tcttaaagat tctacataaa attcttgtat
    55321 gttatgattt ttatagattt caccatcatc aaataggtca acttttttaa atccttcaac
    55381 tataggactt gagtaaggca cagctctaag tattccttcc ttacagagta tatttatggc
    55441 atttcttacg ggtattctac ttatgttaaa taggtcagca atctttctct cacttggtaa
    55501 tttactatta attttaaaag ttccatttag aatgtttaat ttaatataat caataatttt
    55561 ttcagtggca tttaagcttt tcataaaaac tcctaaacat ataatttttt tatgattgta
    55621 ttatatcata gttaagagtt aaatctactt ttttataata tgtataagac aggatagagg
    55681 ccaaaatagc tataatagcc aagataaagt atccatattg tattgaagta tattccgata
    55741 ttttaccaac tatcattgga aatacagaca ttcctatagc ataaattgct tgaaaaaaac
    55801 ccattgcagt agatttctga tgttttggta catttttcat agactcgcta gtaaggtaag
    55861 aaaggagtat acctgtagat atacctggta gcacttgtag tacaaatatt atattaatat
    55921 tttttattgt tggaactaaa aagcaatagg ctgaaactaa aataaaaact aaaggaatcc
    55981 aaaattttgg cccatactta gtacaaaatt tagtagaagc aaagccagaa gaagcaacag
    56041 cacacaccat gtaaaatata gaagatagac ctatgagggt agaactagaa cctaagtttt
    56101 taagaatttg agtagtaaat gacattgttg tagacatttg aataccctgt tgaattaatg
    56161 ccataaagga aaaaaataca agtcttttat ccttgcagat agataaatat tttttaattg
    56221 atattttttc aggtattttt tttgaattat gattttttat atttaaggct agaattgttc
    56281 caataactga agacaataca ctcatgatac ataaggctgt cattcctaat ttttcataaa
    56341 ataaagtact cataacaaat ccaatcaaca ttcctagatt gtttaccaat attatcgtac
    56401 ttgtagctct ttgttgatgt tctgtagaaa aaaagttggt atagtgaacc atgtaagaaa
    56461 tccaagttga tgatgatatt ccagataaaa tgttagctat aagaaaacca ttgcctccag
    56521 gagagaagac tcttataaga gatgctaaac cagcaaagaa aattccagac agtataaata
    56581 ttttatgttt atttatggaa tccgcaaata ctccaacagg aagccttaat aaacattgtg
    56641 agattccata tgcacctatt attataccaa tcatatttgt agatacatta catgcactta
    56701 aatatggatt ttggaaaggt atatatacat attgtgaaaa ccagaaaaat gtaacaatag
    56761 aaagtaaaag taatttttga ttagatattt ttttcatatt atcctccgta tggtattttt
    56821 ataatgcaaa taatatacca tttggatttt ttaatcaagt actttatcta ttaaaaaaaa
    56881 tttaaatata taatcattat ttacaaaaaa attatacttt atagttgaat taagaaaacg
    56941 cttatgatac tataaagtta acaaatttga atatataaca gtagacgtgt tactggtaat
    57001 gcaggcaaga tcgaatcaat ttttatagat tatctataga gtactatggg tataatctat
    57061 ttatttggtt cgattttttt gtttaattgg ccataaaaca aaaagcctat agttgaaaat
    57121 ggaggatttt ttatggatta taaaaatata gctcaagaaa ttctactaaa tgtaggagga
    57181 aaagagaatg taaatgaagt gactcattgt atgacaagac ttagatttaa agtcaaaagc
    57241 gcttctaaag tgaataagga taaattatct aaaactgaag gagtaataac tgttgttgag
    57301 agtatgggtc aaatacaagt tgtaattgga aataaagtaa aaaaagtata tgatgaggtc
    57361 ataaaaattg tacctcaatc aaataacgta ggtaaaaaga atgaaagtca agaaaagcaa
    57421 ggtataatta attctatatt atcagcagta gctggtatat ttacacctac aatacctgct
    57481 atagcagggg ttggtatgat taaaggtatt ttatcagttc ttgctatgta ttatatgaat
    57541 aaaaatggag tagatataaa agaaacgcaa agctatatta tcttaaatgc tatggctgat
    57601 tctatattct attttatgcc tattatacta ggatatactg cggctaaagt atttaatgca
    57661 aataaaataa tatctatggt attaggagct acactttgtt atccaacttt tactgctttg
    57721 atggcaggtg aagaatctgt tagattttta ggattggcag taacaaaagc tacgtataca
    57781 tcatctgtta ttccaataat tattgctata tgggctcttt catacgttga aaaagtatta
    57841 gaaaagtata tacctgaggt aattaaaata ataatggttc caactttatc attggttgta
    57901 atgttacctg caacattatt tttatttgga ccaatcggaa tttatatagg aaatgtcata
    57961 aacttttctt ataagtatat ttatgaatta agcccagcat tgtgtggagc atttgtaggt
    58021 gggttatggt gtgtattggt tatatttggt gctcatagag cattattacc aataggtata
    58081 agtgatgttg ctcaaacagg aagacagaat ttattggcgt ttgcaggatc tgcaaacttt
    58141 tcacaagcag gggctgctct aggagtattc tttaaaacta aaaatcaagg actaaaaaca
    58201 atttctatgt ctgcaactat aacagcttta tttggtataa ctgaacctgc aatatacggt
    58261 gccaatctta gattaaaaaa acctatggta tgtgccgtaa tatgtggtgc atttggaggt
    58321 gcgataatgg gaatgggtgg agcttatggt aatgcatttg caaaccaagg tgttttaact
    58381 atacctgtat atgctgaagc aggtgcatta ggtttcttaa gttatctagg tggttgtgct
    58441 atagcatttt ttggttcagc tatttcaact tatctagttg gatttgaaga tttggaagag
    58501 tcttctaata aggaaaattc atctataaaa gtagaaacga aggatggtgt tattgatata
    58561 acttcacctg tagagggcga atgtatagaa ttgtcagaag taaaggatga tgtatttgct
    58621 tcaaaagcta tgggagaagg tatagctgtg ttacctacaa aaggagtaat aacagcccct
    58681 actgattgtg aagtagcttc tttatttcca acattacatg caataggatt aaaattagat
    58741 aatggagcag aaatgttaat acatgttgga atcaatacag tagagttaaa tggtaaatac
    58801 tttacaaaac atgttaatca aggagattta gtgaaaaaag gtgataaact tatatcgttt
    58861 gatatagata aaataaaaaa ggctggttat gatgtaacta cgccagttat agtaaacaat
    58921 acatttgatt aaaaaatagc tactaactcg tgactttagt catgagtta
//
LOCUS       DAFAZV010000023        58475 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFAZV010000023 DAFAZV010000000
VERSION     DAFAZV010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 58475)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 58475)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..58475
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.023"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..764
                     /locus_tag="KOU88_002052"
     CDS             <1..764
                     /locus_tag="KOU88_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3211941.1"
                     /translation="LIKPLRNERNGYREYSDENVENIKKIAYLRTLGITIDDIRNIIL
                     QKVSLVEVVEKQEKVLETKISDLENAKTMCNKMLESDELSYLNLKVEQYITELPEYWN
                     KNKPVFKLDSVSFLYIWGGKITWGIITIACLLIAITVFPKLPPQIPIQWNNGVANYVD
                     KKFIYAYPVICVVFRILLRPFIWRWLQIHAFYSDTIADYLTNFMCFVALSIEIFSILF
                     IYNIARHVTIIIFIDILVFIALLIIGVYKLFKKYN"
     gene            complement(1014..2390)
                     /locus_tag="KOU88_002053"
     CDS             complement(1014..2390)
                     /locus_tag="KOU88_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211942.1"
                     /translation="MKYKIGFLTTSYFMSDKFKQALKELNDTCEITFIELKGENPFNN
                     LPNIYYEQVDNFDGFVCSGIVPYSELIINIKDIKVPLNFLKLDERDFYKYLFKLLNSQ
                     KDIDFTKSFMDFLREDNNYYDIYSLIDSNKCPYTIKDFNIPQPVYDFKKLNDKLLEIH
                     LDLLRDNKINLSFTRNYIISCELNKLGYDCIYMVPSTESILNTFKSLVNEITLQNLDK
                     NKSATCIVTVNSSEYINEDLIFKNDEIQNQIYNTILNSLSRHGFYGVQVKKNDMKIEI
                     HTTKEMLNNMTNNYTDFFISEDLKEIKYSLNIGWGIGNTNIHAEQNARQANGKSASLN
                     GNCTFIVNDTNDTIGPLYSNKNSNNIEDSSIANKVASFIPLSNTNVSKIMCMINDRNS
                     NNVSAEILADYMNITLRSANRILSILYKAGIATIVNTKLDNQRGRPKKIYKVDFLSFL
                     NKMQKLNS"
     gene            2658..3830
                     /locus_tag="KOU88_002054"
     CDS             2658..3830
                     /locus_tag="KOU88_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK3211943.1"
                     /translation="MNTYLNEISKFVDENREEIVSLWKEIVNMESYTHCKESVNKLAE
                     RLKLEFEKEGLDCELVDVGDNGSTLIGTLGSNINKKPIIFSGHMDTVFETGTFGENPF
                     KIIEGKAYGPGVLDMKGGIIISLYVIKALNKIGYKERPIKIVFSGDEEIGHKDSTGAD
                     VILREAKGGLCAFNMETGLVDNSLCVGRKGRIGCNIHVKGVETHAGNDFEGGRNAIEE
                     MANKILRIQKLTNLDVGTTVSVSVIKGGRVENSIPEDCSIKVDLRFEKVEEMENVKEQ
                     VREICKETYIEGTSTEVNFISEMMPFETTEDVMRFHTFVNEVSKENGFGELNAKRLGG
                     SSDASYLTIANVPTICSFGVRGEWNHTSREYAVVDSMFERVKLISTVILNLDKFEV"
     gene            3844..4491
                     /locus_tag="KOU88_002055"
     CDS             3844..4491
                     /locus_tag="KOU88_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211944.1"
                     /translation="MDVTAGDNKVTWKGYLSLFVLIVLFSGVFKDSQGFLKALDFANL
                     TGSFGTIADGVDFMGKGGTGAKDGFLFALTLIPTVCFAVGLIDVVESMGGMKAASKIF
                     NPLLRPLLGIPGIAGIAFVSSFTSSDVASIMTKELFESGEITDDERTIFVAYQYAGSA
                     VILNTINTQAPLLPIALLALGPIILIEIFCKILGANLVRLIIGVRNKKNKAKEAV"
     gene            4493..5002
                     /locus_tag="KOU88_002056"
     CDS             4493..5002
                     /locus_tag="KOU88_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBK3211945.1"
                     /translation="MSQQNTGNAIVNSKPKKTSVEIFMGGAKKGFYIGVEQILPAMIM
                     GYVIVQFLQLTGLVDILGNIFGPVMGIFGLPGESVVVLIAAFFAKAAGAATAANLFAQ
                     GLITAPQATILIMPCMLMGTLVGHYARIVLVANASTKYRMLLLAVPIFDAIVGMLIVR
                     VLLTVMGLM"
     gene            complement(5366..6478)
                     /locus_tag="KOU88_002057"
     CDS             complement(5366..6478)
                     /locus_tag="KOU88_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBK3211946.1"
                     /translation="MKISEVATPNFLLDLDQLEKNIDKIQQICTNNNKQLWPMLKTHK
                     STYIARLQKNAGASGFLVGTLDEGEALIKAGFEDIMLAYPYMGEVNINRIVTMASKIN
                     LICATDNIECAKAYSEAFSKSKIECKLLIIVDCGLHRFGVEPEKVVELATEISKLENI
                     KIVGISSHPGQVYGCSSPEGVPDVCVQEDSSMEKAYKALTDNGFNIEIVASGSTPTVE
                     SEAASKTITAVRPGNYVYYDAIQIGLGCATEDMCALTVVCTVISKNSSGYYLIDCGSK
                     CLGLDKGAHGNSSIVGYGRVCGHPELTIDSLSEEVGKIKVNGETDIKIGDRIRIIPNH
                     SCSTANLTSNLLGFRGDTIEKVIEVDIRENSKQIIL"
     gene            6776..7042
                     /locus_tag="KOU88_002058"
     CDS             6776..7042
                     /locus_tag="KOU88_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase family protein"
                     /protein_id="HBK3211947.1"
                     /translation="MNLEPKKLIEQIGKEKDKKDIWIVGGGDIVKLFMKDNLIDDYYI
                     YILPIILGRGISLFKSGIDKTNLNFKKASNIGELVKLEYSKKQK"
     gene            7287..9014
                     /locus_tag="KOU88_002059"
     CDS             7287..9014
                     /locus_tag="KOU88_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003496244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211948.1"
                     /translation="MKLILSYLKNYKLLIVLNILAIFSFALVELGIPTIIAKIIDNGI
                     ANQNIAYIKQMGIVIVIISIIGVVGSILLGYCSAKVSTSVTRDIRNDIFEKSQEFSHT
                     EYNKFGISSMITRTTNDAFQIQQFVNILLRTALLTPVMFIISIIMTIRTSVELSIVLA
                     ISVPFIIIGVAIIAKVSQAISSKQQKGLDKLNLISRENLTGIRVIRAFGNDDYETERF
                     EKTNTYYANVSKKLFKLMSITQPAFFLLLNIAVLAVFWISSEKINIGELQVGQLVAFL
                     EYLFHAMFSIMLFSMVFIMYPRAEVSANRIKELLNEEPLIKNPENGIKDTENKGIIEF
                     DNVTFTYPDGEASVLKDISFTAKTGETVAFIGSTGSGKSTLINLIPRFYDVTEGSIKI
                     NGVDIREYDLKALRKKIGFIPQKSLLFTGSIANNIRFGKHKAGESELEYSAKVAQAYE
                     FISKKPRKFDELISEGGANVSGGQKQRLSIARAIIRRPEIYIFDDSFSALDFKTDAIL
                     RSKLKKETKDAIVLIVAQRISSIIDADKIIVLNEGQVVGMGTHKELLKNCEIYYEIAT
                     SQLKKEELE"
     gene            9014..10804
                     /locus_tag="KOU88_002060"
     CDS             9014..10804
                     /locus_tag="KOU88_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3211949.1"
                     /translation="MKKSKGFKKTIGRLLPFVKKYKFSFIIAIICIISAATMNALAPK
                     TEGLIITQLTKDVISIAKGVPGASVNFDYVTKILVILACIYFANAIFTYTSSFLLTNA
                     IQNTMRDLRNEVENKIRRLPISYFDSNSFGDVLSRISNDVDTISNALQQSFMQIVNSI
                     LVIILALSMMFTINIYMALIALFIIPISYFVSKFVVKKSQSRFSLQQNALGKLNGKVQ
                     EMYTGFNEIKLYGKEEDSIKEFKKVNQELCENGFKAQFISSMMNPMVSLVTYFGIAAV
                     AVVGSIYAVSGGITVGNLQAFVRYIWQINQPLSQMTQLSTVIQSSFAAIERVFEILDE
                     EEEIPDVENPVKIENVKGNVTFEHVNFGYGENSTLIEDLNAEVKSGQMVAIVGPTGAG
                     KTTLINLLMRFYDVKKGAIKIDGVDIRDMKRKDLRSMFGMVLQDTWLFNGTIFENIEY
                     GRFGATKEEIIQAAKVANVHHFITTLPDGYNMFLNEEASNISLGEKQLLTIARAFISD
                     PSILILDEATSSVDTRLELMLQKAMRNLMNGRTSFVIAHRLSTIRNADLILVMNNGSI
                     IEQGNHDELMEKGGFYEKLYNSQFADKESE"
     gene            complement(10966..11274)
                     /locus_tag="KOU88_002061"
     CDS             complement(10966..11274)
                     /locus_tag="KOU88_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211950.1"
                     /translation="MFNKIYEKKEFIVFQVKKGYVVYNTRKSFEEGHTHLKHFEAAKT
                     AIDLAINKKIPRSKDGYYLTSLIRISDDGYYIDKLSELLYVREQKGKKEKYCNSGYQM
                     "
     gene            complement(11536..12084)
                     /locus_tag="KOU88_002062"
     CDS             complement(11536..12084)
                     /locus_tag="KOU88_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211951.1"
                     /translation="MIFLNEDVVTNETIDKDYAIEEVRMACKHFGDLYFYFSKVLFEE
                     FGEDKTSEILRKVLFERSEERAIAMRERAHENGDELIADNIISTTDVPFLGWVPEFEE
                     LHCPYGASWLLRFEENPWFKKFASLYCDVTDTTVAEVFTGDTSHKITKNILWGDKSCE
                     RIYFHDDKVSEGKYTYGNKNCK"
     gene            complement(12187..12858)
                     /locus_tag="KOU88_002063"
     CDS             complement(12187..12858)
                     /locus_tag="KOU88_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3211952.1"
                     /translation="MATFKRLQEQAYDYLKELILSGKMIENEIYSETKLASEIGISRT
                     PIRDALQRLSQDGFIDIIPSKGFRIHQITANEIVEIFQIRSAIEGFCTFLITSQYKEA
                     RAVETISKLKHLLDKQKDILLGDKNLNSFAEYDTLFHTTIVSYAQNTEFDKMFNNYMY
                     RIKKLALDSLSHEGRLETTLKEHTDIFNNIANGCIEDIYRTTLIHMETPKYINLEDFC
                     NNKLF"
     gene            13254..14159
                     /gene="garR"
                     /locus_tag="KOU88_002064"
     CDS             13254..14159
                     /gene="garR"
                     /locus_tag="KOU88_002064"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBK3211953.1"
                     /translation="MEGYKMKLGFIGLGIMGKPMAKNLLKDGCNLLVYDINKSAVDEL
                     ISCGAKYASVLEMGQECDIVFTILPNGTIVQDILFGMDGLAKTLKEGSIVVDMSSVTP
                     TESILCANKLKDMGLEFIDSPVSGGEPKAIDGTLAFMAGGKEEIYKKVEPFFNIMGSS
                     SILIGDNGSGSVTKLTNQVIVNLTIAAVSEAFVLAAKAGADPEKVYKAIRGGLAGSTI
                     LDAKIPMIMNRDFKPGGKISINLKDIKNVMQTAHNLDVPLPMTSQLLEIMQTLKVHGH
                     LEDDHSGIAQYFEKLAGVEIKKHDN"
     gene            14295..15677
                     /locus_tag="KOU88_002065"
     CDS             14295..15677
                     /locus_tag="KOU88_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBK3211954.1"
                     /translation="MITGYGLLIAFVISIGILLVSIIKFKVNPFLALLITSIITGFMV
                     RMPINEISTTISTGFGNTLGSIGIVIGLGIIFGNILSESRATESIAKGLLAKTGEKNS
                     ALAVTTAGFLISIPVFMDAAFVIMMPIIKYVSRVTKKSLMVFVCALGVGTIVGHALVI
                     PTPGPLAVAANVNANVGSFILYSIIVAFPAALIGGWIYGKRFEKYPAYAIDENDREKN
                     LEQGKDSIKIEDDDSSKVPGFGISMFSLLFPILLILISNVFSMFLEKGSTMSGVLAFI
                     GDKNIAILLGILVAIGFLKKYINKPMGDVVIEAADSAGLILLITGSGGAFGSVINASG
                     IGNFLVDTMSGLSISVVVLGFLLSALLRISQGSATVALVTTSSILGPTILATGMSPVL
                     VGLAICAGGVGFSLPNDSGFWVLSRFSGLSVKDTLNSWTIGGTIAGVVAFIMVLLLSV
                     INGIIPLPGL"
     gene            15748..17184
                     /locus_tag="KOU88_002066"
     CDS             15748..17184
                     /locus_tag="KOU88_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBK3211955.1"
                     /translation="MREVKPISIDILNTFKQVDEDRLNKLLADELKHLDRKIVVLDDD
                     PTGVQTVHDISVYTDWDKDSMEQGFNEKNSMFFILTNSRGFTVAQTTKAHKEISKNIV
                     DVSKKVNKDFIIISRSDSTMRGHYPLETNLLKSEVERLSGKLFQGEIIMPFFKEGGRF
                     TIDNVHYVKEGEILVPAGMTEFAKDKSFGYKSSDIGEWCEEKTNGKYKSSDMIYISSK
                     ELRELNIEAITEKLKKAEGFNKIIVNATDYVDVKVFTIAFIRAVNGGKEFMFRSAAAI
                     TKVLGGVSDKELLTKDELVSKGNTNGGIILVGSHVNKTTQQLEELKNCKYPIEFIEFN
                     QHLVLQENGLKNEVKRVIKVVEEKISSGKTVAVYTRRERFDLDTNDKDKQLMISVEIS
                     DAVTSIIGMLNVRPNFIIAKGGITSSDVGTKALRVKKATVMGQIKPGIPVWMTGKESK
                     FPNMPYIIFPGNVGEISTLRESVEILMG"
     gene            complement(17370..18224)
                     /locus_tag="KOU88_002067"
     CDS             complement(17370..18224)
                     /locus_tag="KOU88_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211956.1"
                     /translation="MSTFYIQFLYFVIYSFIGWCCETTYCSVLQKQFVNRGFLNGPFC
                     PIYGFGALAIVATLTPFVHNIPLLFLFSIIITSIMEYCTSFILEKIFNMTWWDYSKHK
                     FNIHGRVCLENSLMFGVLSLIVMLIVHPIVVDFINSISKNVLFIFAISIEIYFVLDLV
                     ITVHTILQLNGKLKQINLIIKELKDKKEYYKLITQETIENKLESLVENRLDTLEDRFE
                     ILKEKENYRYAKNRIDELKNKLNTLLSNHKLLHRRIIKAFPNISSNKHTDILNKIKEN
                     IKSIKKDK"
     gene            complement(18492..18815)
                     /locus_tag="KOU88_002068"
     CDS             complement(18492..18815)
                     /locus_tag="KOU88_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1540 domain-containing protein"
                     /protein_id="HBK3211957.1"
                     /translation="MERINCNVINCSHNNSHICYADKIFINGEKAHNDRHTCCSSFLD
                     ESIYSNLSSNVNNRNCEELVCTVKNCKYNKDGSLCTLDNILVAPETDRVNLYIETCCS
                     SFECK"
     gene            19018..19647
                     /locus_tag="KOU88_002069"
     CDS             19018..19647
                     /locus_tag="KOU88_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211958.1"
                     /translation="MFEKKKKELFPWKISALILIGVFVLSSGVYIGTRLKHNGVQTGE
                     VVSTSANMNEKSKEAFGLNKNCEVWLQSEGENETNYKRTLTMAGIVPESLLDKTKSEI
                     VSYFKKEYPTKKIKSMDKNEIILVESKYSDNKDVQAMDVTIKGKYTIENDNGNIALYK
                     YDDSGSKTLVEKTKIRVDSLPKTVQDEIKKGVVMDTEEEAYSRLEDFAS"
     gene            19959..20468
                     /gene="ruvC"
                     /locus_tag="KOU88_002070"
     CDS             19959..20468
                     /gene="ruvC"
                     /locus_tag="KOU88_002070"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBK3211959.1"
                     /translation="MIILGIDPGIAIVGYGIIEYKNSKFKAIDYGAVTTPAHMNISRR
                     LELVYKGIDTIVKNYNIDEVGMEELFFNKNVKTAITVAQARGVTMLACAHNGKPVYEY
                     TPLQVKQGVVGYGRADKAQVQQMVTSFLSLKKVPKPDDVADALAVAICHAHSNKLEKT
                     LKNIGGKYV"
     gene            20461..21063
                     /gene="ruvA"
                     /locus_tag="KOU88_002071"
     CDS             20461..21063
                     /gene="ruvA"
                     /locus_tag="KOU88_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBK3211960.1"
                     /translation="MYSYIKGTVEEIYIDSIVVENNGIGYKINVSSNTIMNLQVGEAT
                     KIYTKLIVREDDMSLCGFVSREELKMFELLTSVSKIGPKVALSILSFASPAQLGAYIL
                     SEDIGKLSKAPGVGKKTAERIVLELKDKVDKNNIEFEPTLLSQKPTLISQDESVDALV
                     ALGYTLSESKEAVQKCKKDGMNTEAIIKKALTYIMSKSLK"
     gene            21170..22189
                     /gene="ruvB"
                     /locus_tag="KOU88_002072"
     CDS             21170..22189
                     /gene="ruvB"
                     /locus_tag="KOU88_002072"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBK3211961.1"
                     /translation="MQGFEDENRIITSTMKMEDIDIENSLRPKTLEDYLGQEKSKEQL
                     SIFIEAAKSRNEQLDHVLLYGPPGLGKTTLASIIANEMGVNLRITSGPAIERAGDLAA
                     ILTNLNENDVLFIDEIHRINRSVEEVLYPAMEDFCLDIIIGKGPSARSIRLDLPKFTL
                     IGATTRAGMLTNPLRDRFGVICKLDYYTVDELSKIVLRSSSILDAEIQSNGALELAKR
                     SRGTPRIANRLLKRVRDFAQVRADGKITDKVAKDALELLGVDSLGLDFVDEKLLMTII
                     EKFRGGPVGLDTLAASIGEDRNTIEDVYEPYLLQLGFINRGPRGRVAMPLAYEHLKIP
                     YPNEK"
     gene            22507..23532
                     /gene="queA"
                     /locus_tag="KOU88_002073"
     CDS             22507..23532
                     /gene="queA"
                     /locus_tag="KOU88_002073"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBK3211962.1"
                     /translation="MKTSDFKFDLPQELIAQVPIEDRASSRLMVLDKETGNIEHKVFR
                     DIIEYLNPGDCLVLNNTRVIPARLIGEKLETGGKIEFLLLKRTEEDTWQALVKPGKRA
                     KVGTKFSFGNGKLIGEVVDLSDEGSRIIKFHYDGIFEEILDELGNMPLPPYITARLDE
                     KERYQTVYSKHNGSAAAPTAGLHFTEELLNKIKEKGVDIAFVTLHVGLGTFRPVKVED
                     VLNHKMHSEYYMVSQEAADKINRAKENGKNVICVGTTSCRTIESACNEDGKMKETSGW
                     TEIFIYPGYKFKVLDKLITNFHLPESTLIMLVSAICGKDNVLNAYNEAVKERYRFFSF
                     GDAMIIK"
     gene            23544..24029
                     /locus_tag="KOU88_002074"
     CDS             23544..24029
                     /locus_tag="KOU88_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211963.1"
                     /translation="MHSLQKQKKNNPILKIAFIFERVLAVVVLIAVFLGTIDVLRLMW
                     GAYIVDFQNPVQYSQLNDFLAQILLLVIGVELVVMLSLHIPGAFIEALLYAIARKMLL
                     LPKNEGMIDVLIGVIAIAGLFAIKKFLVTKDKSALNIMSIHDEEAIKEQQNKEDEDKS
                     I"
     gene            24108..25229
                     /gene="tgt"
                     /locus_tag="KOU88_002075"
     CDS             24108..25229
                     /gene="tgt"
                     /locus_tag="KOU88_002075"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBK3211964.1"
                     /translation="MYAVRYELIKTCKQSGARLGRLHTPHGIIETPIFMPVGTQATVK
                     SMTPEELKEIGSQIILSNTYHLYMRPGHELIKRAGGLHKFMNWDKPILTDSGGFQVFS
                     LGPLRKIKEEGVEFRSHLDGSKHFLTPEKAMEIQNALGSDIMMAFDECAPYPSDREYV
                     KNSLERTTRWLKRCKDAHNNTDKQALFGIIQGGMYKDLREQSAKEITNIDLPGYAIGG
                     LSVGEPKPLMYDVLEHTTPLMPKDKPRYLMGVGSPDDLVEGVIRGVDMFDCVLPTRIA
                     RNGTAMTSQGKVVVRNATYAEDFTPLDPECDCYACKNYSRAYIRHLIKANEILGARLI
                     TTHNLHFLLNLMKQIRQAIMEDRLLDFRNEFFAKYGYEI"
     gene            25363..25656
                     /gene="yajC"
                     /locus_tag="KOU88_002076"
     CDS             25363..25656
                     /gene="yajC"
                     /locus_tag="KOU88_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBK3211965.1"
                     /translation="MPQQQIIMSIGLWVVVIAIFYFLMIRPQKKKDKQLKEMRSSLSV
                     GDKVITIGGIVANVAKVEDDVVILELGPNRTKVPFEKWAIGTVKSKKEEIEED"
     gene            25714..26076
                     /locus_tag="KOU88_002077"
     CDS             25714..26076
                     /locus_tag="KOU88_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04086 family membrane protein"
                     /protein_id="HBK3211966.1"
                     /translation="MGKSNYIFKGLGYAYIITLAVLLVYNLFLTFTDIGGDNITMVSS
                     FITTISAAIGGFYTSKHMKEKGLMYGFLVGLLYIVCIFLTVFLAQEKFVFEVGMIYKL
                     LLISAAGGIGGVLGVNFK"
     gene            26142..26285
                     /gene="scfA"
                     /locus_tag="KOU88_002078"
     CDS             26142..26285
                     /gene="scfA"
                     /locus_tag="KOU88_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="six-cysteine ranthipeptide SCIFF"
                     /protein_id="HBK3211967.1"
                     /translation="MENKHVKTLSQATLKQSAAKGGCGECQTSCQSACKTSCTVANQE
                     CER"
     gene            26911..28806
                     /locus_tag="KOU88_002079"
     CDS             26911..28806
                     /locus_tag="KOU88_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp8"
                     /protein_id="HBK3211968.1"
                     /translation="MLSNKKRSMAIVMAGATVMSAAAPIFADNTVTENVDKNYTVSAK
                     DSAKLIEEVRKALEVKFEDTKAGANVNDRVYDIKVDNVNLTNATQLQNKINSLTEGQS
                     LKVTIQDKGHQVLGGKVVDYKIENYKTAQEIVDAVNAYNATLAEDSDNKLTATIKSTN
                     TVEVKRAKDSANVITLNVGDQHLDFSKVITSEEGTFEGYEKSYSDIDSKELHTITVKN
                     ADLQDISAEELFDGIRLTTLGREIVNKVKNGYALTFENEAILTQEQEDSDDKDKPEKS
                     SFDIVLSKANEKPETISVSSKNHKLVRDLHKVLTDVKDGKELKVEVLSGDSRFTTAVE
                     VSKERFKDGEAEAIILVGEDAIVDGLASAPLASQKNAPILLSKKDSLPSEIEAEILRV
                     LGSNLSSKKIYIVGGESKVSKETEEKLSKLGVSKVERVSGEDRFETSLEIAKQLKDTF
                     KTAFVVGGNGEADAMSISARAAQFGAPIIVTGNELDANAEKLLKGKELEIVGGENSVS
                     KEVEDKLVDIDLNNKVERLAGENRKDTNAKVINKYYAGATKAYVAKDGYVGGNGQLVD
                     ALTAAPLAASSKAPIVLTTEELSKSQEEVVELRLKNATKLVQIGEGIAKNAIEKIAEK
                     INLFTKN"
     gene            29269..30672
                     /locus_tag="KOU88_002080"
     CDS             29269..30672
                     /locus_tag="KOU88_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp9"
                     /protein_id="HBK3211969.1"
                     /translation="MKNSKKILAIGLTLFLVMVNTPMVNALTSVEQIKGNDRYETAAK
                     IADKQNYNTAILINSDNSLADGLSASGLAGALNAPILMTKQNQIPNTTMERLNKAKTV
                     YIIGSESTISKNVENQLLSKKKVVQRIFGENRFDTSIKIAEKIKEIKPIDKVIIANGF
                     TGEADAISASPVAARDGVPIILTDGNSVGFDTTGLKSYALGSSEIISDELVKSTNSIR
                     LGGTDRFETNKIVIQEFYKNSKEFYLSKGLQLTDALAASTIAKNAPVVLVENGSNKSI
                     LSGADKLTVLGGINQNVIKQCINQASPNQQGLYYNPNDRAFKERIKGKVYALTKQYRK
                     ENGVRALSVASRLEGLANDWSNLMANKKTLSHTINGKNSYSTFLKYLDWSEIKPGYIA
                     VQGENIIKYKIPDKPVYTNRDADDIGNFIFNEWKTNPEEGTNMLHKGYEIMGFGIAIT
                     GDKNLYATHEFYGRYKE"
     regulatory      30844..30929
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            31053..36995
                     /locus_tag="KOU88_002081"
     CDS             31053..36995
                     /locus_tag="KOU88_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-binding adhesion protein"
                     /protein_id="HBK3211970.1"
                     /translation="MKKAISCVLAVSMCSAPLNVFAEPILEGKLRAVEKSVTEKLRGS
                     LEVDLNFSLPIKNSESESMTNMQLRLKDDSNNSGIIKLGEKDSGTVNVGTDNIEYTIK
                     KLSASRSEIKNKDENISYYNIVFNNLPVGKYNVEVSGAGFKNKEIKDIDISSYSQRVL
                     LSNRASVDNKNKPLNYELFLMGDVNGDGKVDKSDYNKVLENIDSNKSEFDLNRDGKVD
                     IVDLDYVQKNLGQSEDAKSLESIVSTNPIVDTSKVELKGNSDVDINGNVENLFSGENN
                     GVTISSKNDKICEEKPAVMDIALSEALNMEVINIKAPEGTAPAKGIVEVTDKDGNVQQ
                     IPYENKEYMKNLKDEEQQEEVNNEQEEVNQEEVNNKDENIEQIDNNSNNKDENSDKQE
                     ANSNTNQDKNNDKENSSMDKPDLGEDTPKKESNISKDDNSTTSTYSRSVLETYADVQN
                     SDIVINLGKQVAVKKITIKITATTANDRNLAEISKVEFLNNLYKEIPKPEMNIPKINK
                     ISTSTAVGNEKVSFYWNNEVNVSAYELILDKIDSKGKVLSTKKLQTSKNTIEVRDIEA
                     YGLYRVSIQSLNGDWSSGYKDATPENLDGVPENVDSNYKPIQFSPDSILEFQVVPDTK
                     PEPPEGINVKGKFKSLDVSWKNHKQAKDFDLYYKEKGSNGSWIKYNDKLIRGTSSKIE
                     GLKDNTTYEVRMTATNHLGTSGMSKTYIGTTESMDAPTTPNYRLINTPKENGGFGIPT
                     NHIVDVTYPAGYDKSEYSDKNPFDKFNVVDGDFTTHWTFPTYNAAEGTNRGPIITFDK
                     SYTMDTFMVTPRFDVSDKTINDFEVRYWDENGQLHNLGNVPFETKTDPVNNNKYVMVR
                     LKEPITATKIQVSVCSSYSYKSNISELKFYEYDSIEDDVRNLFMDDLQVELKEDVTQE
                     KITELKDRLNTPDKASGEYHPYKTVIDRELKLAQDLYNDRATLTDVTTVNQEINKSGK
                     YKDKNGQYTVNSNNLGMQNDWQALGVAARAGDEITVYVGSKSGKTPKLIYTQYYGESG
                     AYKSGEINLKTGKNVIQLSKLHSLDIECGGSLYIRYPEDTPSGGDIKVRVAGATKIPH
                     LNLNGTINDKSPAGVSESKKKIKAYIEELAKYKDAVKGEPYYPGTNVGNSYGYSDKTG
                     VLNTTDIESDKVTLNVPATAIYQGISKGNADLNTQVDRFYNSMLAWEQIMDLVYSERG
                     VFKTQDLDGNGTVDDNEFNLTKNDMAPKSRMNIKYQRMFIGAFMYASGLHVGVEYGSV
                     PGLMNGVPFQIDDSGKATGGNLFGWGIGHEIGHVTDIGKMTYSETSNNVLALLAQTFD
                     DKTHSRLEGSTMDKIYEHVTSNSLGIPSNVFERLGMLWQLHLAYDDDFTGSMLKNNSD
                     VDLSNDTFYAKISRKYRALSSSDPINSLPKDQMLVAMASSVVEKDLRDYFKAWGVEIT
                     PELNSIMDSKNYEKESRKIQYVNDEARRKTLNENIASMAKDTKVSASFSDGIQSGSLV
                     KSSKISIDLDVDKDKDKILGYEIIRSDGNYLEGENGTQVKYRTVGFVDAKGNSKAKFT
                     DNISPLNNRAFTYKVVAYDYHLNPTEEFEVGTVKLSDEGKINKSAWSFITNTVSDGDV
                     RTENDSHGPLQNPEIDNIKDNDASTTYKGKIISKAEWNKDPQKDPDINVEENPYIIVD
                     MKETLPIVGLKYTKPKTETRKFSLKGLFNFRKDTSTTYNPLTNYKIQVSNDKKNWEDV
                     SQGTFEYGQDLVGGGKDQDNEARVTFNKDGKLWTYQARYVKLISNNKSNIEVAELDII
                     GPPGDNIEIGTMNNADQTRTNGIGKLAEDYVYQSDDPSTSEDETAKIPAGSIVITGEY
                     SGNPAFNLPLLIDKNNKTISGESLLFAEVPEKGELGEISKGTWVYYMPKENFDSLSDK
                     VKAELYRYNDLQGDTPVGQRFVSDTMCVPVGAKNYDELKTISLTDSNSKARKATRNAI
                     DVSNKKVITVSNRVKVNIVRDK"
     gene            37206..39086
                     /locus_tag="KOU88_002082"
     CDS             37206..39086
                     /locus_tag="KOU88_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp10"
                     /protein_id="HBK3211971.1"
                     /translation="MSKRKSFIRTIAVSTMAVAVTGSATCAYAAPVLQGTKTYEKVNT
                     IDISVDSVENIVYSFQASIKVQGEVEVVDNEQKEKITWSDNIKSQIKSGNANATCRAE
                     YNKSSNTTTLDIYVTSNEDLLDGNRLNIGRISVKKSGSNSNADYKVLGKGTSDKPALK
                     IVTYNNKTVDYENINSDEGLIFTLINESEVKPIGGTGSSKNDPEKYKVEKSEALEYLL
                     NNIRINYSIVSKETQESGSNVILKLGLAQKTTKGRKATINKYVEVTLPKSLEYIVENE
                     LSKPDELPPDNGNGGNNGGGSNSGGSSSGGSSGGGNSSDSTSNVTVKKLKGVDRFETA
                     VKISQSGWTKSDTVVIVNGEDKSMVDGLTATPLASVKNSPILLSSNEKLPQKTVEELK
                     RLNPSKVIVIGGNNSMPNSVVEAIKAVNSKISVQRISGDTRYQTSINIAKEIDKTNNV
                     SKLYIGAGNGEADSLSIASLAGKEKTPIVLTQKDGVDNEAEQFIKSNKVSNIYFIGGV
                     EKISNKAIEQVGKIANKDISNNRVAGQTRQETNAKVIDKFYSQSKLDGVVVANQDKLI
                     DALAVGPLAAKNNSPVILATNTLDKSQESSLKGKNSSKLFEVGGGIASSVIDKIKSLI
                     EK"
     gene            39453..41054
                     /locus_tag="KOU88_002083"
     CDS             39453..41054
                     /locus_tag="KOU88_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp11"
                     /protein_id="HBK3211972.1"
                     /translation="MKMNKKILSLGLAVSLILVNFKSVNASSVVEKIYGKDRYETAAK
                     IADKQTYETVILVNTEKSLADGLSASGLSGATKAPILFTQQNKIPADTNRCLKNIKKA
                     YIIGTEDTISKSVEKELDSKNIEVKRIGGEDRLKTSYLIAKEIATIKKVDKVLLTNAY
                     SGEADAMSVSSVATRDGAPIILTDGKSVPFDVKNIQSYCIGSEEIMSNHLVKNTNSVR
                     IEGTDRFETNKNVIDYFFNSADGFYVSDGYQLVDAIAAAPLTKNSPMVLVNDGSDKTV
                     LEGAKNITSVGEINEKVIQQCINASKSNGQPPTITVGSTEIYKGEKFDTGKLNIVAKD
                     NTGKVLPIEVDGFIDTNRVGTYILTLKATDEWGKSTGKRVEIKVLDDKSHDYNSPEFK
                     KMVSTEMYNLINSYRKEKGKEPLVVSSKLEGMANAWSKYMMDKKVFAHYIDGKNAPQV
                     FSEFGMRSEENIAYIYIDSKNVQTTQDAKDLAKAIFEVWKKSPEYNANMLSDEFYSTG
                     FGLYILSDGQVHATQEFLNGNEGIL"
     gene            41273..42871
                     /locus_tag="KOU88_002084"
     CDS             41273..42871
                     /locus_tag="KOU88_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBK3211973.1"
                     /translation="MKVNKRVLSIGLTISLIMAGAPNINALSSIEKIQGKDRYETSAL
                     IADKQIYDTVILVNTDNSIVDGLSASGLSGVVKAPIMLVQRDKIPTDVEKRLKDVKNA
                     YVIGTEDTIGKSVENQLKNKGIEVKRIGGEDRIKTSYLIAKEISAIKPVNDGDKVFLV
                     NGYTGEADAMSVSSVAARDGVPVILTDGKSIPFKVDGVQCYSLGSEEIMSNELVSKTN
                     SVRIAGKDRFETNKKVIQRFYKGTKKFYVSQGYKLVDAVAGSPLAKDKPIVLVNDGSD
                     KSVLRGADEVTSLGGMDKKVVDQCISSASDKNTMPTITANDVEISVGDKFDNSMLNIV
                     ATDYYGNNLKPNIEGTVDTSKAGTYVLNISAFDNFGQKCEINVNVKVIINTSTKDPNS
                     YEFKAMVSNEIYNLVNSYRDEKGKKPLKELKSLTGMANAWSKYMYEKEIFAHEINGKN
                     AAEVFSGFGMRSGENIAYLPMNTQSIYGDKEAKEIANSIFDLWKKSSKYNDNLLKSEF
                     YSFGFGMYVSSNSEVHATMEFLNS"
     gene            43107..44939
                     /gene="slpA"
                     /locus_tag="KOU88_002085"
     CDS             43107..44939
                     /gene="slpA"
                     /locus_tag="KOU88_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-layer protein SlpA"
                     /protein_id="HBK3211974.1"
                     /translation="MKKRNLAMAMAAVTVVGSAAPVFAAASDVISLQDGTNDKYTVSN
                     TKASDLVKDILAAQNLTTGAVILNKDTKVTFYDANEKDSSTPTGDKKVYSEQTLTTAN
                     GNEDYVKTTLKNLDAGEYAIIDLTYNNAKTVEIKVVAASEKTVVVSSDAKNSAKDIAE
                     KYVFEDKDLENALKTINASDFSKTDSYYQVVLYPKGKRLQGFSTYRATNYNEGTAYGN
                     TPVILTLKSTSKSNLKTAVEELQKLNASYSNTTTLAGDDRIQTAIEISKEYYNNDGEK
                     SDHSADVKENVKNVVLVGANALVDGLVAAPLAAEKDAPLLLTSKDKLDSSVKSEIKRV
                     LDLKTSTEVTGKTVYIAGGVNSVSKEVVTELESMGLKVERFSGDDRYETSLKIADEIG
                     LDNDKAYVVGGTGLADAMSIASVASTKLDGNGVVDRTNGHATPIVVVDGKADKISDDL
                     DSFLGSADVDIIGGFASVSEKMEEAISDATGKGVTRVKGDDRQDTNSEVIKTYYANDT
                     EIAKAAVLDKDSGASSSDAGVFNFYVAKDGSTKEDQLVDALAVGAVAGYKLAPVVLAT
                     DSLSSDQSVAISKVVGEKYSKDLTQVGQGIANSVINKIKDLLDM"
     gene            45181..47523
                     /gene="secA"
                     /locus_tag="KOU88_002086"
     CDS             45181..47523
                     /gene="secA"
                     /locus_tag="KOU88_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBK3211975.1"
                     /translation="MTVLDRIVDKSDELEIKVLNYIVDDIETLEPKMESLSDEELKDM
                     TNIFKDRLKQGETLDDILQEAFAVVREVSKRVLGMRQYRVQLIGGIVLHQGKIAEMRT
                     GEGKTLVGVAPIYLNALLGKGVHVVTVNEYLAQRDKETMQPVYEFLGLSVGVITSDLL
                     PEDRKKQYNCDITYGTNNEFGFDYLRDNMVTRKSEKVQRELYYSIVDEVDSILIDEAR
                     TPLIIAGSGKEDTKLYELANAFIKTLKDKDYEIDKKENTVCLTHTGLSKAESFFGIEN
                     ITNIDNIEIYHHTNQALRAHKLMERDVEYVVKDEEIQIVDEFTGRILDGRRYTDGLHQ
                     AIEAKEGVKIKDESKTLATVTFQNFFRLYEKLSGMTGTAKTEESEFESIYKLNVVQIP
                     TNKPVIRADLQDKVFRTEDAKYNAVVEEVIKINKTKQPVLVGTVSIEKSEMLSKLLKK
                     RGIKHEVLNAKQHDKEAEIISRAGKLGSVTIATNMAGRGTDIALGAGDKIEEKKVRDI
                     GGLYVIGTERHESRRIDNQLRGRSGRQGDPGTSRFFVSLEDEMIKLYGGKGIEKILKR
                     MNAKDEDAIESKSLSKAIERAQRGIEGKNFEQRKNVLKYDDTINEQRKVIYEERNRVL
                     NDLNISEDIQKMVREIIEDAANKYLSNQRDYYGYFKSLYNDFMPPNTLLIPGVDKKSV
                     DEVVQHTYEISKRVYDIKKMEVGIDKIEELEKRVLLQVVDTYWMDHIDAMDQLRQYIG
                     LKSYAQKDPFKEYALEGYDMFEELNRKIRTTTVQYLYKFD"
     gene            48134..49999
                     /locus_tag="KOU88_002087"
     CDS             48134..49999
                     /locus_tag="KOU88_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBK3211976.1"
                     /translation="MNIPKKIISLLTITIMLSGLSLNTVNASTKESLVGSGRWETAIQ
                     ISKNGWENSKEAVLVNDSSIADALSATPFAKAKNAPILLTQSNSLDARTKAELKRLNV
                     SKVYLIGGNVTLSSNLEYELKSININSERISGDSRYSTSLELAKKIDSINTISKIVVV
                     NGQKGLADAVSVGAAAAQGNMPIILSDTTNGTSTSKDFISKHNITTSYVIGGTNSVSE
                     DIKNSLPNAKRISGENRNQTNAKVVEEFYKGTNLKNLYITKDGMKKQGDLIDSLAVGV
                     LAAKNSSPVLLAGNKLDSVQKDILDTKIFDKITQVGGNGNEDVFKSIQDIQEETKYTV
                     ETISELDTAIKKSDANDIIRFKNDDKITGSIDISTKKAITIEFNGLYSGKVNINIPNG
                     DVYNYGDMTGQMDIKDIKTDTLVNEGSINEITIYDPNGCKIENEKDADIWKITLLDTS
                     KNTYINNSGTITKIVSDASNTTIKNSGKIELISGTKSPAVSGNQATDENIKDNDDKEA
                     GGISVYVDPCSPPKEGKVMLRIPKEPRSSSYNIYYRIVKSRPSAMDVGDTISKRGWTK
                     VTTRDSFMISATDGYYVEAVEIYDSDRKVSKWGRSGSIDDGYNNTTSSATLRSYK"
     gene            50308..50766
                     /locus_tag="KOU88_002088"
     CDS             50308..50766
                     /locus_tag="KOU88_002088"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211977.1"
                     /translation="MNITNKCVLGISILAILSFGFSAFQGNAQITDRKKDYDIYLKAN
                     SDKSDVKSSLNDISKLEKKYGESDALSISKINLYEKMNDYKNLQSEIEKVYNRYPQTR
                     NTVSFVLLYSEVALKNGNKELSKNMINEAIKLGAQDAYKERVDKVLSQLN"
     gene            50779..52386
                     /locus_tag="KOU88_002089"
     CDS             50779..52386
                     /locus_tag="KOU88_002089"
                     /inference="COORDINATES: protein motif:HMM:NF016800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBK3211978.1"
                     /translation="MLDKYYNRGKVEQIDKFILFILLFMMCIIPIITHEYTSTNYSPI
                     FTLTLYSSGERVEIFNFYKTAILYLGTMIVFCFFMYKIFVLKEELKKRKVNIILLILA
                     IGVILSSVFSDYKDIALFGNPDRFEGALAWFCYIVIFFVLYNIKIDVKDLKLFYFGLF
                     PFLVINLFLGLAQFFEIDVLQSKILTTLIGGGTLSGTFWTTLYHFNIMSGIASVIFCA
                     SLVYMLFEKDIKKKIVPLFGAIMSFTIILISNSISGFLTSILLFPIILVLSWRFVNKK
                     ELCVWTIIMVIISSIIYIILNRHNPNVYQETFAMFEKLNQASIFIVPILIVTFILLII
                     IMKFINKKKFFNFVTVCSIVIVSAGLLFFSYTLNKEVSILESNPNANITRIEDSKLFN
                     IINGMSTDRLNIWTKVMNFINERPILGNGFDTFPYKFISTDKNGALSTYGEVIDKPHS
                     WYMSVAYGSGIIGIIGLVGIIIYLTKEVFYSCVDKNNDKFLYIFFIGFLAYSIQGLFN
                     DSLAGSSIISWVFAGLTANRIFTIKSK"
     gene            52585..53544
                     /locus_tag="KOU88_002090"
     CDS             52585..53544
                     /locus_tag="KOU88_002090"
                     /inference="COORDINATES: protein motif:HMM:NF025025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3211979.1"
                     /translation="MNVSIIIPTKNAEKYIENLIKALINQTIEPCEIIVIDTESKDKT
                     VEICMEYDIVKFIQIKQSEFGHGSTRNRAAKLSKGDILVFMTQDALPQNCYFIEELIK
                     PLGKNNIVCTYGRQLPRNNAKTLEVFSRSFNYGNSDIIKSKEDIPKLGVKTFFFSNVC
                     SSFIKRDFFLVDGFPENIIMNEDMIISSKIIYNGKKTCYASKAIVTHSHRYTYLQQFK
                     RNFDIGVAFKENSYYLSEVKSESEGFKFVIEAIKFLFQSNKCYLIPSLFIESGFKFFG
                     YKFGMNYKNMPIKLVKLMSMHSFYFDRKEVMEEYYSENSNNRC"
     gene            53519..54370
                     /gene="rfbD"
                     /locus_tag="KOU88_002091"
     CDS             53519..54370
                     /gene="rfbD"
                     /locus_tag="KOU88_002091"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBK3211980.1"
                     /translation="MKIVITGAKGQLGLEIVNQLDNLNNIREKNIYDIVPTDRSNLNI
                     TDLENVNNFIFKEMPDVVINCAAYTKVDLCENDIDNAYKVNALGVRNLATACEKIKAK
                     FVQISTDYVFDGNSNIPYKEDCITFPNSIYGKSKLMGEYFTRQFSSKYFIIRTAWLYG
                     DGDNFVRTMLNLAKNNNEINVVDDQIGSPTSTVELAEAIINLIETDYYGIYHGTCEGE
                     CSWYEFANKIFELSKITVKVNPITSNEFKREAPRPMYSVLDNFMLKLIGLNNFNRWDE
                     ALKKYLE"
     gene            54398..55276
                     /gene="rfbA"
                     /locus_tag="KOU88_002092"
     CDS             54398..55276
                     /gene="rfbA"
                     /locus_tag="KOU88_002092"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007060455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBK3211981.1"
                     /translation="MKGIVLAGGSGTRLYPITKCVSKQVLPIYDKPMIYYPISVLMLS
                     GIRDILIISTVRDIKIFKELFGDGSQLGVNIQYAIQEKPNGIAEAFIIGEDFIGDDKV
                     ALVLGDNIFYGYGFSERLERAINRDEATIFGYHVSDPTSFGVVEFDKDFNVLSIEEKP
                     KIPKSNYAVPGLYFYDNEVIKIAKSIKPSKRGELEITSVNNEYLKKGKLKVELFGRGM
                     AWLDTGTHRGLLDASNYVEVVQTRQGLYIACLEEIAYIKGYITKEDLLELAKPLMKTD
                     YGKYLIKIANEFKENK"
     gene            55484..56380
                     /locus_tag="KOU88_002093"
     CDS             55484..56380
                     /locus_tag="KOU88_002093"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211982.1"
                     /translation="MNSWRDTLYTPTSIEKIDDLYFIVDCWQHRVIYNDNLSDKISNW
                     KTLSDNLEGPHSIASDKEVFLVDNTEKNEIQVFKRKEDNFILTQTIQNVGKRPHKIIY
                     DKNTNLFYSIASTSQDIVVLENINGNVRVKQKTRLDFLDGSYIRSISIIEDKMYFLPG
                     PNKVICTDYKSGKFNVISEYKLPKALEAINHLYKIDNYYYISLYTMGENPNEPKLVRF
                     KNFNELQNNEYEDLTKKLNIKGVPYFFSEFDGKVFFTEIDSYSEIKSFKVNNDNIDSI
                     VNYYDSGKPSKESIERKKSILR"
     gene            56424..56996
                     /gene="rfbC"
                     /locus_tag="KOU88_002094"
     CDS             56424..56996
                     /gene="rfbC"
                     /locus_tag="KOU88_002094"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003467069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBK3211983.1"
                     /translation="MSKFNFIETKLKDLYIIEPTIFGDSRGYFMETYNKREFLEAGLD
                     MEFVQENESKSKKGVLRGLHFQTENVQGKLVRVAFGEVYDVAVDLRIGSPTYGLWEGV
                     ILSSENKRQFYVPEGFAHGFLVLSNEAVFNYMCTNYYNADYEGGILWNDKDINIEWPL
                     DKVDSVILSEKDKKLLKLSELDLQFKYGGE"
     gene            57000..58022
                     /gene="rfbB"
                     /locus_tag="KOU88_002095"
     CDS             57000..58022
                     /gene="rfbB"
                     /locus_tag="KOU88_002095"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBK3211984.1"
                     /translation="MSKVLITGGAGFIGGNFVHYILDKYPKYEVVNLDLLTYAGNLET
                     LENIKHKHNYKFVKGDISNRNFIFDLFDEERFDIVINFAAESHVDRSIKEPWKFINTN
                     VIGTQVLLDASNKYGVNRFHQISTDEVYGDLPLDRLDLLFTEKTNLNPSSPYSASKAS
                     ADLLTISYYKTYGLPVTISRCSNNYGPYHFPEKLIPLVIHRALENKELPIYGDGKNVR
                     DWLHVYDHCTAIDLIVHKGKSGNIYNVGGHNERSNLEVVKTILDTLGKSEDLISFVAD
                     RKGHDLRYAIDASKLEQELGWKSIYSFDEGIKHTIKWYLENQEWMESIISGEYKNYYS
                     NMYKNE"
     gene            58043..>58475
                     /locus_tag="KOU88_002096"
     CDS             58043..>58475
                     /locus_tag="KOU88_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008706116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3211985.1"
                     /translation="MSLVKELYRNRDLILNLSKNDFKTKYAGSYLGIFWAFVQPVVIV
                     LIYWFVFQVGFKAAPVKDFPFILWLIAGIVPWFFFQEALINSTNSLLEYSYLVKKVVF
                     KISILPLVKIISALYVHIFFICFALASYCIYGIYPNIYIIQI"
BASE COUNT        23089 a         6418 c        10238 g        18730 t
ORIGIN      
        1 atttaattaa accccttcgt aatgagcgta atggctatag agaatattca gatgaaaatg
       61 tagagaacat caaaaaaatt gcatatttac gtacattagg aattactatt gatgacatcc
      121 gtaatattat attacaaaaa gtatctttag ttgaagttgt agagaaacag gagaaagttc
      181 tcgaaactaa aatatcagac ttagaaaatg caaaaactat gtgtaataaa atgctagaat
      241 ctgatgagct aagttatttg aatttgaaag tagagcaata cataactgag ttgccagaat
      301 actggaataa aaacaaacct gtttttaaac ttgactctgt aagtttctta tatatatggg
      361 gagggaaaat tacctgggga attattacta ttgcttgttt gttgattgca ataacagtat
      421 ttccaaagtt gccacctcaa attcctatcc aatggaataa tggtgtagct aattatgtag
      481 ataaaaaatt tatttatgcc taccctgtca tttgtgttgt attcagaata cttttacgtc
      541 catttatatg gagatggtta caaatacatg ctttttatag tgatactatt gcagattatt
      601 taacgaattt tatgtgtttt gtagcgttgt ctatagaaat attctctata ctttttattt
      661 acaatattgc cagacatgtt acaataatta tttttataga tatacttgta tttattgctt
      721 tactgataat aggtgtgtat aaattattta aaaaatacaa ttaattttta aaaataagta
      781 ataagtgata gtgtaaaaag tagccactgc aaattatgga ttgtagtggc tattttatta
      841 tttgtatatg aaattatttt gtttttctaa taagttacga tatattatgg tttatttcac
      901 tgataaaagg tttaggtatt ttaaagtaaa aagttgtata ttctaataaa atttaaacat
      961 tttgattcct taaaattaga gaaaatacat tgcttttatt aaaaaattaa atattaagaa
     1021 tttaatttct gcatcttatt tagaaaagat aagaaatcaa ctttatatat tttttttggc
     1081 cttcctcttt gattatcgag ttttgtattt acaatagttg caattcctgc tttatataaa
     1141 atactcaata ttctattagc acttctaaga gttatgttca tatagtctgc taatatttct
     1201 gctgacacat tatttgaatt tctatcatta atcatacaca tgattttaga tacatttgta
     1261 ttagatagag gtataaaaga agcaacttta ttggctattg agctatcttc aatattatta
     1321 gaatttttat ttgaatataa aggacctatt gtatcattag tatcatttac tataaaagta
     1381 cagtttccat tcaaagaagc agatttacca ttagcttgac gagcattttg ctctgcatga
     1441 atatttgtat ttccaatgcc ccaacctata tttaagctat atttaatttc ttttaaatct
     1501 tctgaaataa aaaaatctgt atagttattg gtcatattgt ttaacatttc tttagtagtg
     1561 tgtatctcta ttttcatatc attttttttg acctgaactc catagaatcc atgtcttgat
     1621 agagaattta atatagtgtt atatatttga ttttgtatct catcattttt aaatatcaaa
     1681 tcttcattta tgtactctga actatttact gtaactatac aagttgcaga tttatttttg
     1741 tctaagtttt gtaatgttat ttcattcacc agagatttaa atgtattcag gattgattct
     1801 gtagatggaa ccatgtaaat acaatcatat ccaagcttat taagttcaca actaatgatg
     1861 taatttctag taaaagaaag gttaatctta ttatctcgca ataagtctaa atgtatttcc
     1921 aataatttat catttaattt tttaaagtca tatacaggtt gagggatatt aaaatcttta
     1981 attgtatatg gacatttatt agagtctatt aatgaatata tatcataata attgttgtcc
     2041 tctcttaaaa aatccataaa tgattttgta aagtcaatat ctttttggct atttaataat
     2101 ttgaataagt atttataaaa atctctttca tcaagcttta aaaaatttaa tggaactttt
     2161 atgtctttta tatttattat aagttcacta tatggaacta taccactgca tacaaatcca
     2221 tcaaaattat ctacttgctc atagtatata ttaggtaaat tattaaaagg attctcccct
     2281 ttgagctcaa taaatgtaat ttcacaagta tcatttaatt ctttaagagc ttgtttaaac
     2341 ttatctgaca taaaataaga tgttgtcaaa aaaccaattt tatatttcat aaaacctcct
     2401 ttaaaatttc gagagtattg taactaatca atcaatttat aacctcattt tataatagta
     2461 gataaaacgc gtcaatttat tttacaaaag gaaaattgaa agaaaaatca gaaaatataa
     2521 aaaagactga aaaatatgtt gactggcaag aataattgtg ctattttgta attaaggact
     2581 agtcttttaa gatttcctaa aataaactta gattttagga aagaaataca ttttatttga
     2641 aaataaagga gaagattatg aatacatatt taaatgaaat ttctaaattt gttgatgaga
     2701 atagagaaga aatagtttca ttatggaaag agattgttaa tatggaaagc tatacacatt
     2761 gtaaagaaag tgtaaacaag ttagctgaga gattaaagct tgaatttgaa aaagaaggtt
     2821 tagattgcga attagtagat gttggagata atggtagtac attgataggt acacttggtt
     2881 ctaatataaa taaaaagcct ataatttttt caggtcacat ggatactgtc tttgaaacag
     2941 gtacatttgg agagaatcca tttaaaataa tagaaggaaa agcatatggc ccaggtgttt
     3001 tagatatgaa gggtggtata ataatttcct tatatgttat taaagcatta aataaaatag
     3061 gatacaaaga aagaccaata aaaatagtat tttctggaga tgaagagata ggacataagg
     3121 attcaacagg tgcagatgtt atattgaggg aagcaaaagg tggtctttgt gcttttaata
     3181 tggaaactgg attagtagat aatagtttgt gtgtaggtag aaaaggaaga ataggatgta
     3241 atatacatgt aaaaggtgta gaaacacacg caggtaatga ttttgaaggt ggaagaaatg
     3301 ctatagaaga aatggctaat aagatactac gcatacaaaa attgactaat ttagatgttg
     3361 gaactacagt aagtgtaagt gtgattaagg gtggaagagt ggaaaattct attccagaag
     3421 attgtagtat aaaagtagac cttagatttg aaaaagtaga agaaatggag aatgttaaag
     3481 aacaagttag agagatatgt aaagaaactt acatagaggg aacttctaca gaagttaatt
     3541 ttataagtga aatgatgcca tttgaaacta cagaagatgt tatgagattt catacatttg
     3601 taaatgaagt gtcaaaagaa aatggatttg gagaattaaa tgctaaaaga cttggaggta
     3661 gttcagatgc aagttattta actattgcaa acgttcccac aatctgttca tttggtgtaa
     3721 gaggagaatg gaaccacaca tcaagagaat atgcagtagt agattctatg tttgagaggg
     3781 tgaaattaat ttctacagtt attttaaact tagataaatt tgaggtataa agggggattt
     3841 tatatggatg taacagctgg agataataag gtaacatgga aagggtattt atctttattt
     3901 gtattgatag tattattttc aggggtgttt aaagatagtc aaggcttcct taaagcatta
     3961 gattttgcta atctgacagg ttcatttggt actattgcag atggtgtaga ctttatgggt
     4021 aaaggaggaa cgggagcaaa agatggtttc ttatttgctc tgactttgat tccaactgtc
     4081 tgttttgctg taggtcttat agatgtagtt gaatctatgg gaggaatgaa agcggcatca
     4141 aagatattta atccattgct tagacctctg cttggtatac ctggaatagc aggaatagca
     4201 tttgtatctt catttactag ttcagatgta gcctcaataa tgacgaaaga attatttgaa
     4261 agtggggaaa taacagatga tgaaagaact atatttgtag catatcaata tgctggttca
     4321 gctgttatac tgaacacaat aaatactcaa gctccacttt taccaatagc attattggca
     4381 ttaggtccaa taatccttat agagatattc tgtaaaatac ttggtgctaa tctagttaga
     4441 ttaatcatag gtgtaagaaa taaaaagaat aaggctaagg aggctgtgta gtatgagtca
     4501 acaaaatact ggaaatgcaa ttgtaaatag taaacctaag aaaacttctg ttgagatatt
     4561 tatgggggga gcaaaaaaag gtttttacat aggtgttgaa cagatattac cagccatgat
     4621 aatgggttat gtaatagtgc agtttttaca attaactggt ttagttgata ttttaggaaa
     4681 tatttttgga ccagtaatgg gtatttttgg actacctggg gaatctgttg tagttttgat
     4741 agcagcattc tttgctaagg cagcaggagc agctacagct gcaaacttat ttgcacaagg
     4801 tctaatcact gcaccacaag caaccatatt aattatgcca tgtatgttaa tgggtactct
     4861 agttggtcat tatgccagaa tagtgcttgt agcaaatgcc agtactaagt atagaatgtt
     4921 actgttggca gttcctatat ttgatgcaat agtggggatg ttaatagtaa gagttttact
     4981 cactgttatg ggattaatgt aaataacata aaattataac ctaactataa atgatatata
     5041 agaattaata tatacaagga ttaatgagta gtaattgata tatagtaata aactaagata
     5101 gtaattaatg tgtatattaa ttaaaaaaag agagtatctc aaagtgaact ttttagttca
     5161 tgagatactc tttttgtatg aaatcaagta tattttcata atttcaacaa tgaaagagag
     5221 gcttatcttt attttgagac agcctcttct tttaaattta tatttctaga atttatgttt
     5281 tttatttatc caacattaac attagttatt aacaataatt ttaagaaaaa tatactttca
     5341 tgttaatatc agaataaatg tgtttttaaa ggatgatttg ttttgaattt tcacgaatat
     5401 ctacttctat gactttttct attgtatctc ctctaaaacc taataaatta cttgtcaagt
     5461 ttgcagtgga acaagaatga ttaggtataa ttcttattct atcaccaatt tttatatcag
     5521 tttcaccatt tactttaatt tttccaactt cttctgaaag tgaatcaata gtaagttctg
     5581 gatgtccaca taccctacca taaccaacaa tactactatt tccatgtgca cctttatcaa
     5641 gtccaaggca cttacttcca caatcaatta aatagtatcc actgctattt tttgagatta
     5701 cagtgcacac aacagtaaga gcacacatat cttcagtagc acaacctaaa cctatctgta
     5761 tagcatcata gtatacatag tttccaggtc ttacagcagt tatagtttta gaagcagctt
     5821 cagattcaac tgttggagta ctaccagaag cgacaatttc tatattaaat ccattatcag
     5881 ttagagcttt gtatgctttc tccatagaag aatcttcttg aacacaaaca tctggaacac
     5941 cttctggaga actacaacca tacacttgac ctggatgcga acttatacca acaatcttga
     6001 tgttttctag cttagaaatt tcagtagcaa gttcaaccac tttttctggt tcaaccccaa
     6061 aacggtgtaa gccacaatct acaataataa gtagcttgca ctctattttt gatttagaaa
     6121 aagcttcact ataagcctta gcacattcta tattatctgt agcacagatt aaatttattt
     6181 ttgatgccat agtcacgatt ctatttatat ttacttctcc catgtaagga taagccaaca
     6241 taatatcttc aaaacctgct tttatcagag cttcaccttc atcaagtgtt ccaactagaa
     6301 aaccactagc acctgcattt ttttgaagtc tcgctatgta agtactttta tgtgtcttaa
     6361 gcataggcca aagttgttta ttattatttg tacaaatttg ttgaatttta tctatattct
     6421 tttctaactg gtctaaatct agcaaaaaat ttggagtagc gacttctgaa attttcatgt
     6481 tatttaccac ctttcaacaa aagtaaatta actataagta ttataattat tatattagta
     6541 atatcggctt tataatatta atagcttata attatattat agaactagcg ttaacagaga
     6601 gcaatattta tttgtaataa ttagaatttt caataagtta gtgtagtttt aaattattta
     6661 tataatatat ttttaatttt atgcaaagtt tatttaaatt agtttgagga tttattaata
     6721 gggtattatt gaatgagtaa aaaagtgatg tttacataga ataatcacac tataaattaa
     6781 tttagaacct aaaaaattaa ttgagcaaat tggaaaagag aaggataaaa aagatatttg
     6841 gatagttggt ggaggcgata tagtaaaatt atttatgaaa gataacttaa ttgatgatta
     6901 ttatatatat atattgccaa taatattggg gagagggatt tcactattta agtctggtat
     6961 agataagact aatttgaatt ttaagaaagc tagtaatatt ggagaacttg taaaattgga
     7021 atacagtaaa aaacaaaaat aaattacatg ccaatttgtt acaatgttat gaaacgaagc
     7081 atttaaaaga cttttggcta tatgaattga cattacttgt caaatatgtt aacatataag
     7141 cgacttgtcg gagggtgtat taaaaagaat atgctggaga agagagtgcg ttaactcttt
     7201 tctccttttt ttataaaatt aagcatttat aaatttagta ttattacatg attacactat
     7261 ctcaaaaatt aagaaaggag aaaaatatga aattaatttt aagttattta aagaattata
     7321 agttattaat agtattaaac atactggcta tatttagttt tgcattagtc gagttgggga
     7381 ttccaactat aatagctaaa ataattgaca atggtattgc aaatcagaat atagcttaca
     7441 taaaacaaat gggaatagtg attgttatta tttctattat aggggttgta ggtagtatat
     7501 tgttgggtta ttgttctgct aaggtatcaa caagtgtaac cagagatata agaaatgaca
     7561 tatttgagaa atcacaagaa ttttcacata ctgaatacaa taaatttgga atttcttcaa
     7621 tgattacaag aacaacgaat gatgcatttc aaattcaaca atttgttaat atactactaa
     7681 ggactgcctt attaactcca gttatgttca ttataagtat aataatgacc attagaacaa
     7741 gtgtggaact ttctatagta ttggctatat cagtaccttt tataattatt ggagtagcaa
     7801 taatagcaaa agtatctcag gcaatatctt caaaacaaca aaaaggacta gataaattaa
     7861 accttatatc gagagaaaat ttaactggaa taagagtaat tagagctttt ggaaatgatg
     7921 attatgaaac cgagcgattt gaaaaaacaa atacatatta tgctaatgtt tctaagaaat
     7981 tatttaagct tatgtcaatt actcaaccag cattcttttt actattaaac atagctgttt
     8041 tggctgtatt ttggatttca agtgagaaga taaatattgg agaacttcaa gttggacagt
     8101 tggttgcatt tttggaatat cttttccatg ccatgttttc aattatgctt ttttcaatgg
     8161 tatttattat gtatccaaga gcagaggtat ctgcaaatag aataaaagaa cttttaaatg
     8221 aagaaccatt gataaaaaat cctgaaaatg gaattaagga tactgaaaat aagggtatca
     8281 tagaatttga taatgtaact tttacctatc cagatggaga agcttctgta cttaaggata
     8341 tttcatttac tgcaaaaaca ggtgaaacag tcgcttttat aggaagtact ggtagtggga
     8401 aaagtactct aattaacttg atacctagat tttatgatgt aacagaaggt agcattaaga
     8461 taaatggagt agatataaga gaatatgatt taaaagcttt aagaaaaaag ataggattca
     8521 tacctcaaaa atcactgctt tttactggta gcatagcaaa taatattaga tttgggaaac
     8581 ataaggcagg agagtcagaa ttagaatatt ccgcaaaagt tgcacaagca tatgagttta
     8641 tatcaaaaaa acctagaaag tttgatgaat tgattagtga aggtggagca aatgtatcag
     8701 gaggtcaaaa acaaagactt tctattgcaa gggctattat aagaagacct gaaatataca
     8761 tttttgatga tagtttttct gcacttgact ttaaaactga tgcaatactt cgttctaaat
     8821 tgaagaagga aacaaaagat gcaattgtat tgattgttgc ccagagaatt agttctatta
     8881 ttgatgctga taagattata gtactcaatg aaggacaagt tgtaggaatg ggaactcata
     8941 aagaattatt aaaaaactgt gaaatatact atgaaattgc aacatctcag ttaaaaaagg
     9001 aggaattaga ataatgaaaa agtctaaagg ttttaagaaa acaattggta gacttcttcc
     9061 atttgtaaag aaatataaat tttcctttat tatagctatt atatgtataa tttcagcagc
     9121 tactatgaat gcacttgcac ctaaaactga aggattgata ataacacaat tgactaaaga
     9181 tgtaattagt atcgcaaaag gagtaccagg ggcttccgta aattttgatt atgtaacaaa
     9241 aatattggtg attttagcat gtatatattt tgccaatgca atttttacgt atacttcaag
     9301 ttttctactt acgaatgcta ttcaaaacac aatgagagat ttaagaaatg aagtcgaaaa
     9361 taaaataaga agattgccta ttagttattt tgatagtaat agttttggag atgtattaag
     9421 tcgtatatca aatgatgtag atacaatatc aaatgcattg caacagagtt ttatgcaaat
     9481 tgtaaactca atcttagtca taattttggc actttcaatg atgtttacaa ttaatatata
     9541 tatggctctt atagctcttt ttataattcc aattagttat tttgtatcta aatttgtagt
     9601 aaaaaaatct caaagtagat tttcattgca acaaaatgct cttggaaaat taaatgggaa
     9661 agtacaagaa atgtatactg gatttaatga aataaaacta tatggtaaag aagaagattc
     9721 tataaaagaa tttaaaaaag taaatcaaga actttgtgaa aatggattta aggcacaatt
     9781 tatatcaagt atgatgaatc ctatggtttc attagtaact tactttggaa ttgcagctgt
     9841 ggcagttgtc ggttctatat atgcagtaag tggaggaata acagtaggaa atttacaagc
     9901 atttgtgcgt tatatatggc agataaatca gccactttca caaatgactc agttatctac
     9961 agtaatacaa tcttcttttg cagctataga acgtgtattt gaaattttag acgaagaaga
    10021 ggaaatacct gatgttgaaa atccagttaa gatagaaaat gtaaaaggaa atgttacatt
    10081 tgagcatgtt aattttggat atggagaaaa ttcaacttta atagaagatt taaatgcaga
    10141 agtaaaaagt ggtcagatgg tagctattgt tggacctact ggagcaggta aaacaacatt
    10201 aataaactta ttgatgaggt tttatgatgt aaagaaaggt gctattaaaa ttgatggagt
    10261 agatataaga gatatgaaac gtaaagattt gcgttcaatg tttggtatgg tgcttcaaga
    10321 tacatggtta tttaatggaa ccatttttga aaatatagaa tatggtagat ttggggctac
    10381 taaagaagaa attatacaag cagcaaaagt agcaaatgtt catcacttta taaccactct
    10441 tccagatgga tacaatatgt ttttaaatga agaagcatct aatatatctc taggggaaaa
    10501 acagctttta accatagcta gagcttttat atcagaccct tcaatattga tacttgatga
    10561 agctacgagt tctgttgata ctaggctgga acttatgctt caaaaagcaa tgagaaatct
    10621 tatgaatggt agaactagtt ttgttatagc acatagactt tctacaattc gcaatgctga
    10681 cttgatttta gttatgaata atggaagtat tatagagcag gggaaccatg atgaattaat
    10741 ggaaaagggt ggattttatg agaagcttta taatagccaa tttgcagaca aagaatcaga
    10801 atagataaca taaacttttg tataaaattt tgtatcaaat tcaaatatta atcatataat
    10861 taaaaagagt atcagtaagt tgttttttta tagatttact gatactcttt gattttaaga
    10921 ctaaaggtac ttatgattgg tacttataat tcacaactag tcttgttaca tctgataacc
    10981 agaattacag tacttttctt ttttaccttt ttgttctcta acatataaca attcgcttaa
    11041 cttatcaatg taataaccat catcacttat gcgaattaaa ctagtcagat aatatccatc
    11101 tttgcttcta ggaatctttt tatttattgc taaatcaata gctgtctttg ctgcttcaaa
    11161 atgctttaaa tgtgtatgac cttcttcaaa actctttcta gtattataaa ctacataacc
    11221 ttttttaact tgaaaaacta taaattcttt cttttcatat attttattaa acattcaatc
    11281 agcccttctc aagatagttt tatagcataa cattagaagc ttctaaaaaa ttttacaaag
    11341 aacataaata ttttataaat tataaatcta aaactataat ttataaagat aactttctga
    11401 ttatttatat gataattcat atagattaaa agtaaattat ctttaggtta aacaaaagta
    11461 aaataaaaga ctagttataa tatttatatg aaaaagtaca aaatatagta tatgaatata
    11521 gaaaatttaa attatttatt tacagttttt atttccataa gtatatttac cttcagatac
    11581 cttgtcatca tggaaatata ttctttcaca acttttatct ccccatagaa tgttttttgt
    11641 tattttatgg gacgtatctc ctgtaaatac ttcagctaca gtagtatctg taacatcaca
    11701 gtaaagagaa gcaaattttt taaaccaagg attttcctca aatcttaaaa gccaagaagc
    11761 tccatagggg caatgtaact cttcaaattc aggaacccat cctagaaatg gaacatcagt
    11821 tgtgctaata atattgtctg cgattaattc atctccattt tcatgagctc tttctctcat
    11881 agcaatagct ctttcttcag acctttcaaa taaaactttt cttaatattt cgctagtttt
    11941 atcttcacca aactcttcaa ataacacttt ggaaaaataa aaatataaat caccaaaatg
    12001 tttgcatgcc atacgaactt cttcaatagc ataatctttg tcgatagttt cattagttac
    12061 aacatcctcg ttcaaaaaaa tcactcctta gaataagtat tagttacaat ataattatag
    12121 aatatttttt ataaattagg aaattaattt gagatagata tatttttaat aaatgaaagt
    12181 ataatgctaa aataacttat tgttacaaaa atcttctaaa ttaatgtatt taggagtttc
    12241 catatgaatg agagtagttc tgtaaatatc ttcaatacat ccatttgcaa tattattaaa
    12301 aatatctgtg tgctctttta atgttgtttc aagccttcct tcatgtgaca atgaatcgag
    12361 agctaatttt tttattctgt acatataatt gttaaacatt ttgtcaaatt cagtattttg
    12421 agcatatgaa actatagttg tgtgaaataa tgtatcgtat tctgcaaatg agtttaaatt
    12481 tttatcacct aataaaatat ctttttgttt atctaaaaga tgttttaatt tacttatagt
    12541 ttctactgct ctagcttctt tgtattgact tgtaattaaa aaagtacaaa atccttctat
    12601 tgcagagcgt atttggaata tctctacaat ttcatttgct gtaatttgat ggattctaaa
    12661 tcctttgctt gggattatat ctataaatcc atcttgacta agtctttgaa gagcatctct
    12721 tataggtgtt ctagagatac ctatttcact agcaagtttt gtttcagaat atatttcatt
    12781 ttctatcatt tttccagata gtatcaattc ttttaagtag tcatatgctt gttcttgtaa
    12841 tcttttaaat gtagccatac ttaataatac ccccctaaac aatataaaaa tacaaaaact
    12901 tatataattt taagcataca acatagtgaa aataaggtca atcttttgca atttaaattg
    12961 cagataagat taaaaaatat aaaaaattat tgaagtgtga agcatgatta acattaaagg
    13021 cagattaatt aaaactaatt gaaattagtt aaaatacaaa actgtaaaag tagtatatta
    13081 tatttgaaaa caatagtatg tattaaaact tatataggat gactaaatat aataaatgac
    13141 tttaaaaatt actatttatt gttaaaataa atacttttat attttatatt gaccggtata
    13201 ctggtatgta gtatactcta aaacataaaa aacgttttca aaaatgtgaa gatatggagg
    13261 gttataaaat gaaattggga tttattggat taggaataat gggaaagcca atggcaaaaa
    13321 atttattaaa agatggatgt aatcttttgg tgtatgacat taataaatct gctgtggatg
    13381 aacttatatc atgtggagca aaatacgcaa gtgttttaga aatgggtcaa gaatgtgata
    13441 ttgtatttac aatccttcca aatggaacta ttgtgcagga tatattgttt gggatggatg
    13501 gattggcaaa aactttaaaa gaaggaagta tagtagtcga tatgagttca gttactccta
    13561 cagaatccat attgtgtgca aataaattaa aagatatggg cttagaattt atagactcac
    13621 cagtaagtgg aggggagcca aaagcgattg atggtacact tgcttttatg gctggtggta
    13681 aggaagaaat ttataagaaa gtagagccat tttttaatat aatgggaagc tcatctattt
    13741 taattggaga taatggtagt ggaagtgtta caaaacttac aaaccaagta atagttaatt
    13801 tgacgatagc agcagtttct gaggcatttg tacttgcagc aaaagcaggt gcagacccag
    13861 aaaaagtata taaggcaata agaggaggcc tagctggtag tacaatattg gatgcgaaga
    13921 taccaatgat tatgaatcgt gattttaaac caggtggaaa aatatctatt aatttgaaag
    13981 atattaagaa tgtaatgcaa acagcacaca atttagatgt accactacct atgacaagtc
    14041 aattattaga aattatgcag acattaaaag tacatggaca tttggaagat gaccatagtg
    14101 gaatagcaca gtattttgaa aagttggcag gtgttgaaat aaaaaaacac gataattaat
    14161 atttaaatat atcaatataa ttaaatacat attattagga ttagattata taaatacagc
    14221 gaggttaagt tatcatagta aaagaaaaat aaaattgata aataataaag tagaatgata
    14281 aaggggtaaa gattatgatt acaggatatg gacttttgat agcatttgtt atatctatag
    14341 gaattttact tgtatcgatt attaaattta aagtaaatcc gtttttggca ttactgataa
    14401 catctataat tacaggcttt atggttagaa tgcctataaa tgaaatatca accacaatat
    14461 cgactggatt tggaaataca ttaggtagta taggtattgt aattggactt ggaataatat
    14521 ttggaaatat tctttcagaa tcaagagcaa cagaatctat tgcaaagggg ttgttagcta
    14581 agactggaga aaaaaacagt gctttagcag taactacagc aggtttttta atttcaattc
    14641 cagtttttat ggatgcagct tttgttataa tgatgcctat aattaagtat gtttcgagag
    14701 taactaagaa atctctaatg gtttttgtat gtgccttagg agttgggact atagtaggtc
    14761 atgcacttgt aatacctaca ccaggacctt tggcagttgc agcaaatgta aatgcaaatg
    14821 taggtagttt tatactttat tctataattg ttgcttttcc agcagctctt ataggtggat
    14881 ggatttatgg aaaacgtttt gaaaaatatc cagcttatgc tattgatgag aatgatagag
    14941 aaaaaaattt agagcaggga aaagatagca taaaaattga agatgatgat tcttctaaag
    15001 taccaggttt tggaatttct atgttttctt tattgttccc aatacttctt atacttatat
    15061 caaatgtatt tagtatgttc ttagaaaaag gttctacaat gagtggagta cttgcattta
    15121 taggagataa aaacatagca atacttcttg gaatattggt ggcaatagga tttttaaaga
    15181 aatacataaa taaacctatg ggagatgtag ttattgaagc tgctgattca gcagggctaa
    15241 tattattgat aacagggtca ggtggtgcgt ttggcagtgt tataaatgca agtggtatag
    15301 gtaacttctt agttgatact atgtctggtc ttagtatatc agttgtagta cttggattct
    15361 tattaagtgc cttgcttaga atttctcaag gttctgctac tgtagcctta gtaacaacat
    15421 catcaatttt aggacctaca attttggcaa ctggaatgtc accagtttta gtagggcttg
    15481 ctatatgtgc tggaggagtt ggtttctccc ttccaaatga ttctggattc tgggtacttt
    15541 caagatttag tggattatca gttaaagata ctttaaactc ttggacaatt ggaggaacca
    15601 ttgctggagt tgtagcattt ataatggttt tattgcttag tgttataaat ggaattatac
    15661 cacttccagg tctataaata acaaactatt gtttatatca tataaattat atttagacta
    15721 tacaaattac ataaaggggc gttttaaatg agagaagtaa aaccaattag catagatata
    15781 cttaatactt ttaaacaagt agatgaggat agattaaata aacttcttgc agatgagctt
    15841 aagcatttag atagaaaaat tgttgtatta gatgatgacc caacaggtgt acaaacagtt
    15901 catgatattt ctgtttatac tgattgggat aaggatagta tggaacaagg ctttaatgag
    15961 aaaaatagta tgttttttat acttaccaat tcaaggggat ttactgttgc tcaaactaca
    16021 aaagcacata aagaaatttc aaagaatatt gtggatgtat caaagaaagt taataaggat
    16081 tttataatca taagtcgtag tgattctact atgagaggac attatcctct tgaaactaat
    16141 ttattaaaaa gcgaagtaga gagattatcg gggaagttat ttcagggtga aataataatg
    16201 ccatttttta aagaaggtgg taggtttact atagataatg tacattatgt taaagaagga
    16261 gaaatacttg taccagcagg aatgactgaa tttgcaaaag ataaatcttt tggatataaa
    16321 tcatctgata taggtgagtg gtgtgaagaa aagacaaatg gaaagtacaa atctagtgat
    16381 atgatatata tttcgtcaaa agaacttaga gagctaaata ttgaagctat aacagaaaaa
    16441 cttaaaaaag ctgaaggatt caataaaatt attgtaaatg caaccgatta tgtagatgta
    16501 aaggtattta caattgcgtt tatacgagca gtaaatggtg gtaaggaatt tatgtttaga
    16561 agcgctgctg ccataacaaa agtacttggc ggagtgagtg acaaggaact acttactaag
    16621 gatgaattag tatcaaaagg taataccaat ggaggaatta tacttgttgg ttcacatgtg
    16681 aataagacta cccaacagtt agaagaactt aaaaattgta aatatccgat agaatttata
    16741 gaatttaatc aacatttagt tcttcaagaa aatggtctaa aaaatgaggt aaaaagagtt
    16801 ataaaagttg tagaggaaaa aataagcagt ggtaaaactg ttgctgttta tactagacga
    16861 gagcgttttg acttggatac gaatgataaa gataaacagc ttatgatttc tgtagaaata
    16921 tcagatgcag ttaccagtat aattggtatg cttaatgtaa gaccaaattt tattatagct
    16981 aagggtggaa ttacttctag tgatgttggt actaaagcac taagagtaaa aaaagctaca
    17041 gtaatgggac agataaaacc tggtatacca gtatggatga caggcaaaga aagcaaattt
    17101 cctaatatgc catatataat tttccctgga aatgtgggag agattagcac acttagagaa
    17161 tcagttgaga tattgatggg gtagtatatt agtgtattga agtttaaacg cttaaattta
    17221 ctgtgttaaa agtaaaataa actaaaatta taaattaaga ttaaaaataa tggtatatta
    17281 attagggttt agagtatttt acaaaaaata ttctaaacct taatcttatg tattagtatt
    17341 tttattattt aacttatgtg tttattttat tatttatctt ttttaattga tttaatattt
    17401 tctttgattt tatttaaaat atctgtatgc ttattagagc ttatgttggg gaatgctttg
    17461 attatacgtc tatgaagtaa tttgtggtta gacagcaaag tattaagttt attttttagc
    17521 tcatcaatac gatttttagc atagcgatag ttttcttttt ccttaagtat ttcaaaccta
    17581 tcttccaaag tatccagtct attttcaact aaagattcaa gtttgttttc tatagtttct
    17641 tgtgtaataa gtttgtagta ttctttctta tcttttaatt ccttaattat aagattgatt
    17701 tgctttaact taccatttaa ttgtaaaatt gtatggactg tgataactaa atctaaaaca
    17761 aaataaattt ctatagatat agcaaatata aatagcacat ttttagagat agagttaata
    17821 aagtcaacca caataggatg tactataagc attacaatca atgataatac accaaacata
    17881 agtgagtttt ccagacaaac tcttccatga atattaaatt tatgtttaga ataatcccac
    17941 caagtcatat taaatatttt ttctaaaata aagctcgtac agtactccat tatgctagtt
    18001 ataattatac taaacaaaaa taacaaagga atattgtgta caaaaggagt caaggtagca
    18061 actattgcta atgctccaaa tccatatata gggcaaaatg gaccatttaa aaaacctcta
    18121 tttacaaatt gtttttgtaa aactgaacaa tatgtagttt cacaacacca tcctataaag
    18181 ctataaatta caaaataaag aaattgaata taaaatgtac tcataagcac ctcatttcta
    18241 gttagtataa cactatatac tcgatatttt atttttatga ttaatttact aaattcaatt
    18301 tacatattga ttataccaat ttatagaaat ttatcaaatt taattacagt tagaacatta
    18361 taaacatggt tataataatg aaattttatt taaaataaat aagggtgtca agtataatca
    18421 aactaatagt tgtagatact ctacactatg ttagtttaat tacatttgac acccttatat
    18481 ttatactatg actatttaca ttcgaagcta gagcaacatg tttcaatata aagatttact
    18541 ctatcagttt caggagcaac caatatatta tcaagtgtac ataagctacc atctttgttg
    18601 tatttacaat tttttacagt acaaactaat tcctcacaat ttctattatt aacgttgcta
    18661 gataaattac tataaataga ttcatctaaa aatgaactac aacaagtatg tctgtcattg
    18721 tgagcttttt caccatttat aaaaatttta tctgcataac atatatggct gttgttatgt
    18781 gaacagttaa ttacattaca gtttattctt tccaaagtta ttacctccta aacgattatt
    18841 tattataaat tatgtccata taattacaag aatataacca ttaagagaaa actacctttt
    18901 agaaaatatc tattcttaga gtaatttgaa atataaatat attttcttct aaaatttacc
    18961 taaattgtat aaaaacttac agcttggaga aaataataga aaaaggaggc gtaatcaatg
    19021 tttgaaaaga agaaaaaaga attatttcct tggaaaatat ctgccttaat actgattgga
    19081 gtatttgtat taagtagtgg agtttatata gggacaagat taaaacacaa tggagttcaa
    19141 actggtgaag ttgtaagtac tagtgcgaat atgaatgaaa agtcaaaaga agcttttgga
    19201 ttaaataaaa attgtgaagt ttggcttcaa agtgaaggcg aaaatgaaac taactataag
    19261 agaacactta caatggcagg aatagttcca gagtcattat tagataagac gaagtcagaa
    19321 atagtatcat attttaaaaa agaatatcca actaaaaaaa taaagagtat ggataaaaat
    19381 gaaatcatat tggtagaatc taaatatagt gataataaag atgtacaagc aatggatgtt
    19441 actataaaag gtaaatatac tattgaaaat gataatggaa atatagcact atataaatat
    19501 gatgatagcg gaagtaaaac attagtagaa aaaacaaaaa taagagtaga ttcacttcct
    19561 aaaacagttc aagatgaaat caaaaaaggt gtagttatgg atactgaaga agaggcctat
    19621 tcaagattag aagactttgc aagttaatag taaattaata ttatttcaag ttaaatacta
    19681 agtaagttaa taataaataa tttaatatta aatagattag tattaaaatt gtagtcacat
    19741 ttaattccta taaaaataca ataatttatt tgtaataaat ataaaagtta tattgaggta
    19801 aaatcttgct ttgatataac ttttttattt gattttatat tttacataga gcattttatg
    19861 atttgttaat attatttatg atataatgat ttagaacata agtttttatg agaaatacat
    19921 tttggtattt cttttatttt tagggggaat tttaaaaaat gataatattg gggattgacc
    19981 caggtatagc catagttgga tatggtataa ttgaatacaa aaatagcaag tttaaagcaa
    20041 tcgattatgg agcagttaca acacctgccc atatgaatat atcgagaaga ttggaacttg
    20101 tgtataaagg aattgataca atagtaaaga attacaatat agatgaagtt ggaatggaag
    20161 aattattctt taacaagaat gtaaaaacag ctataacagt tgcacaagct agaggtgtta
    20221 ctatgcttgc atgtgctcat aatgggaagc ctgtatatga atacactcca cttcaagtaa
    20281 aacaaggtgt agttggatat gggagagcag ataaggcaca agttcaacag atggtaactt
    20341 catttttaag tctaaaaaaa gttccaaaac cagatgatgt tgcagatgct ttagctgtgg
    20401 ctatttgcca tgctcattca aacaaacttg aaaaaactct aaagaatata ggtggtaagt
    20461 atgtatagtt atataaaagg tacagtagaa gaaatttata tagacagtat agttgttgaa
    20521 aataatggga taggatataa aataaatgta tcatccaata caataatgaa tttacaagtg
    20581 ggagaagcca caaaaatata tactaaatta attgtaagag aagatgatat gagtctttgt
    20641 ggttttgtaa gtagggaaga acttaagatg tttgaattac taacatctgt atctaaaata
    20701 ggacctaagg tggcgctttc aatactatca tttgcatcac cagcacagtt aggagcatat
    20761 attttaagtg aagacattgg aaaattatcc aaagctcctg gtgttggtaa aaagacagca
    20821 gaaagaatcg tcttagagct taaggataag gtagacaaaa ataacataga gtttgaacca
    20881 acgttattat cacaaaaacc taccttgata tcacaagatg agtctgtaga tgcacttgta
    20941 gctttaggct atactttgtc ggaatcaaaa gaggcagttc aaaaatgtaa aaaagatggt
    21001 atgaatacag aagctattat aaagaaagca cttacatata taatgagtaa atccttgaaa
    21061 tagtatttgg attttataat atttggattt taaaacaata tttaaggagt ttatgtaaat
    21121 ttgaaaatat ataaagtaga ttttcaaaag tacgagagga ggggtataaa tgcaaggttt
    21181 tgaagatgaa aataggataa taacttctac aatgaagatg gaagatatag atatagaaaa
    21241 cagtttaaga ccaaaaactt tagaagatta tttgggtcaa gaaaaatcca aagaacaact
    21301 tagtatattt atagaagcag ctaaatcgag aaatgagcag ttagaccatg tgcttttata
    21361 tggaccacca ggtcttggaa aaactacact agcaagtata atagccaatg agatgggggt
    21421 aaatttaaga attacgtcag gacctgcaat agaaagagct ggagatttgg cagccatact
    21481 tacgaattta aatgaaaatg atgttttatt tatagatgag attcatagaa tcaatagaag
    21541 tgttgaagaa gttttatatc cagcaatgga ggatttttgc ctagatataa taatagggaa
    21601 agggccatct gctagaagca taagacttga ccttcctaaa tttacactta ttggagctac
    21661 tacaagagct ggtatgctta caaatccact tagagataga tttggtgtta tttgtaaatt
    21721 ggactattat acagttgatg aactttcaaa aatagtactt aggtcttcaa gcatcttaga
    21781 tgcagagata cagtctaatg gagcattaga acttgcaaaa cgttcaagag ggactccaag
    21841 gatagcaaat agattactaa aaagagttag agattttgca caagtcagag ctgatggaaa
    21901 aataactgat aaagtggcaa aagatgctct ggaactttta ggagtcgata gtttgggtct
    21961 tgattttgta gatgagaagc ttcttatgac tataatagaa aaatttagag gaggaccagt
    22021 gggtttagat acattggcag cttctatcgg agaagataga aatacaatag aagatgtata
    22081 tgagccatat ttgcttcaat taggatttat aaatagaggt cctagaggaa gagtagccat
    22141 gccattagca tatgaacact taaaaattcc atatcctaat gaaaaataaa aatagattat
    22201 acgagtattt ataaaataaa agagtcatta aattaaaata tttctaaaat ggctaaaaat
    22261 tcaaacatat ccacaaaatg gtaattatat ctgtagatac tgtggataaa cacgataaaa
    22321 attgtgtgta ttgtatctat atattgtgga taagacatgt atatcgtgga aaaatatcta
    22381 tatattgtgg atatggtgtc tgttaaaaat agcaatttct tgatagatta tggtaatatt
    22441 gtggaaaata agttgttttt ttgatattat tgtagctgga gaaattttaa gagaggaagt
    22501 ttaacattga aaacaagtga ttttaaattt gacttaccac aggaacttat agctcaagtt
    22561 cctatagaag atagagctag ctcaagattg atggtattag ataaagagac aggtaatatt
    22621 gaacataaag tatttagaga tataatagaa tatttaaatc caggagattg cttagtatta
    22681 aataatacta gagttatacc agctagatta ataggagaga agcttgaaac tggaggtaaa
    22741 atagagtttt tattattaaa aagaacagag gaagatactt ggcaggcttt agtaaaacca
    22801 ggaaaaagag caaaagtagg gactaaattt tcttttggaa atggaaagct aattggagaa
    22861 gttgtagatt tatcagatga aggttcaaga attataaaat tccattatga tggaattttt
    22921 gaagaaatat tggatgaact tggaaatatg ccactacctc catatatcac tgctagacta
    22981 gatgaaaaag aaagatacca gactgtttat tcaaagcata atggttcagc agcagcacct
    23041 acagcaggat tacattttac agaagaattg ttaaataaaa taaaagaaaa aggtgtagat
    23101 atagcctttg taactctaca tgttggctta ggaactttta gaccagtaaa agtagaggat
    23161 gttttaaatc acaagatgca ttcagaatat tatatggtta gccaagaagc agctgacaaa
    23221 ataaatagag caaaggaaaa tggaaaaaat gtaatatgtg ttggtactac cagttgtaga
    23281 actatagaat cagcttgtaa tgaggatgga aagatgaaag aaactagtgg atggacagaa
    23341 atatttatat atccaggtta taaatttaaa gttttagata aacttattac taattttcac
    23401 ttaccagagt ctacactaat aatgttagta agtgctattt gtggaaagga taatgtttta
    23461 aatgcatata atgaggcagt aaaagaaaga tatagattct tcagttttgg agatgctatg
    23521 attataaagt agggaggtaa tggatgcata gtttacaaaa acaaaaaaag aataacccta
    23581 tattaaagat tgcttttata tttgaacgtg ttttagcagt agtagttcta atagcagtat
    23641 ttttaggaac tatagatgtt ctaagactta tgtggggagc atatatagtt gattttcaaa
    23701 atccagtaca atacagtcag cttaatgatt ttttagcaca aatattactt ttagtaatag
    23761 gtgttgaact tgtagtaatg ctatctcttc atataccagg agcatttatt gaggcattac
    23821 tttacgcaat tgctagaaaa atgttgctac tgcctaaaaa tgaaggtatg atagatgttt
    23881 taataggagt tatagctata gcaggactat ttgctataaa aaagttttta gtaacaaaag
    23941 acaagagtgc tcttaatata atgagtattc atgatgaaga agcaattaag gaacaacaga
    24001 acaaagaaga cgaagataaa tctatttaga caataaatta tatgaatagc ttattacaaa
    24061 tatatcttaa gaaataatga gaaataaata tgattaagga gaactttatg tacgcagtaa
    24121 gatacgaatt gataaagact tgtaagcaga gtggtgcaag gttaggaaga ttacacactc
    24181 cacatgggat tattgaaaca ccaatattca tgccagttgg aactcaagca actgtaaaat
    24241 ctatgacacc agaagaatta aaagagattg gttcacaaat aatacttagt aacacatacc
    24301 atttatatat gagaccaggt catgaactta taaaaagagc tggtggtctt cataagttta
    24361 tgaattggga taaaccaata cttacagata gtggagggtt ccaggtattt agtctagggc
    24421 ctttaagaaa gataaaagaa gaaggtgtag aatttaggtc acacttagat ggttcaaaac
    24481 attttctaac tccagaaaaa gctatggaaa tacaaaatgc attgggttca gacataatga
    24541 tggcatttga tgagtgtgca ccatacccat cagatagaga atatgtaaaa aattctttag
    24601 aaagaacaac aagatggtta aaaagatgta aagatgccca taataatacc gacaagcaag
    24661 ctttatttgg tataatacaa ggtgggatgt ataaagactt aagggaacaa tcagcgaaag
    24721 aaataactaa tattgattta ccaggatatg ctattggtgg acttagtgtt ggagaaccaa
    24781 aaccacttat gtatgacgtg ttagagcata caactccact tatgccaaag gataaaccaa
    24841 gatacctaat gggagttggt agtccagatg acttagtaga aggtgttata agaggagtag
    24901 acatgtttga ttgtgtccta cctactcgta tcgctagaaa tggaactgca atgactagcc
    24961 aaggtaaagt agtagttaga aatgcaactt atgctgaaga ctttactcca cttgaccctg
    25021 aatgtgattg ttatgcttgt aaaaactatt caagagctta tataagacac cttataaaag
    25081 caaatgaaat actgggtgca agattaataa ctactcataa tcttcacttt ttattaaatt
    25141 taatgaaaca aataagacaa gcgataatgg aagatagatt acttgatttt agaaatgaat
    25201 tttttgcaaa atatggatat gaaatatagg ttttgcacta ttaattataa tcattttaat
    25261 atataatatt caatagtact caaagataga gaaagtaaat tgttatataa acatttatta
    25321 tgatttacaa aagagtataa tttacaaagg agtgaaaaat taatgccaca gcaacaaata
    25381 attatgagta taggtctatg ggtagtagta atcgcaatct tttatttcct aatgattaga
    25441 cctcaaaaga aaaaagacaa acaattaaaa gaaatgagaa gtagcctaag tgtaggagac
    25501 aaggtcatta caataggtgg aatagtagct aatgtagcta aagttgaaga tgatgttgta
    25561 atattagaat taggaccaaa tagaactaaa gttccatttg aaaaatgggc tataggaact
    25621 gttaaatcta aaaaagaaga aatagaagaa gactaaatta gtaatttaaa agccttttct
    25681 cgaatatata ttaatttgag aggaggtttt tttatgggaa aatctaatta tatttttaaa
    25741 ggtctaggat atgcatatat aataactttg gctgttttat tagtgtataa cttatttttg
    25801 acatttacag atattggtgg agataatata actatggtct catcatttat aactactatt
    25861 tctgcagcta taggagggtt ttacacttca aaacacatga aagaaaaagg acttatgtat
    25921 gggtttttag taggactttt gtacatagta tgtatttttt tgactgtgtt tttagcacaa
    25981 gaaaagtttg tatttgaagt agggatgatt tataagttat tgttaatatc agcagcagga
    26041 ggcattggag gcgtattggg tgtcaacttt aaatagagtt tatattaaag tagttttatg
    26101 atataatcaa taggaaacaa ttagaaatgg aggcgttgaa aatggaaaat aaacatgtaa
    26161 aaactttatc tcaagctact ttaaagcaaa gtgctgcaaa aggtggatgt ggagagtgtc
    26221 aaacttcttg tcaatcagct tgtaaaactt cttgtacagt tgcaaatcaa gagtgtgaaa
    26281 gatagaaaat tattgattta gttgtttgta agagggtatc tcaaagtgat tcttttatca
    26341 ttatgaggta tcctctttta ttttcaatta ttatataaaa atatatattc tatttatgta
    26401 aaattaaatt tgatttctta tcgtttaatt atgcaaaaat atctaatcat ataagagcat
    26461 ttattttaaa gtagctactc ttatatttta ttttttatca attacatgta ttagaataat
    26521 ttttaatttt aaactctaat ttatgatgat ttttataata tgttatatat tttaatatat
    26581 ggagatagat attaatttag tgatatatat ttaagtaata agagtaaagc aaaaattagt
    26641 gcatagtagt atataaaaat ggagtttgaa tacttttgtt agtatatgat tgtttagtag
    26701 aaaatcacta taaaatagga tttctatctt tgagcataat tatagagagc taagtagggg
    26761 gaagggtttc aagaagatat tattagtgtt tgtgttagta aattatgtaa acacataaaa
    26821 tatattgaaa aataatatta tatataatat tatttatgtg tgggaaatac gaatataaaa
    26881 aataaaaaat aatattcgga ggacataaat atgttaagca acaaaaagag aagtatggca
    26941 atagtaatgg caggtgctac agttatgagt gcagcagcac caatattcgc agacaatact
    27001 gtgacagaaa atgttgataa aaattacaca gtaagtgcga aagattctgc taaactaatc
    27061 gaagaggtta gaaaagcatt agaagttaag tttgaagata caaaagcagg agcaaatgta
    27121 aatgatagag tttacgatat aaaagtagac aatgtaaact taactaatgc aactcaatta
    27181 caaaataaaa taaactcttt aacagaaggg caaagtttaa aagttactat tcaagataaa
    27241 gggcatcaag tgttaggtgg aaaagtagtt gactataaaa ttgaaaacta caaaactgct
    27301 caagaaatag tagatgcagt taatgcttac aatgcaactt tagcagaaga ttctgataac
    27361 aagttaacag caactataaa atctacaaat acagttgaag taaaaagagc aaaagattca
    27421 gcaaatgtta ttacattaaa tgtaggagac caacatttag atttctcaaa agtgataaca
    27481 tcagaagaag gtacttttga aggttatgaa aagagttata gtgacataga ttcaaaagaa
    27541 ttacatacga taacagttaa aaacgcagat ttacaagaca tatcagcaga agaattattt
    27601 gatggaatta gattaactac attaggaaga gaaatagtta ataaagttaa aaatggatat
    27661 gctttaacat ttgaaaatga agcaatcctt actcaagaac aagaagatag tgatgataaa
    27721 gataaaccag aaaaatcaag ctttgatata gttttaagca aggcaaatga aaagccagaa
    27781 acaataagtg tttcaagtaa aaaccataag ttagttagag acttacacaa agtattaact
    27841 gatgtaaaag atggaaaaga attaaaagta gaagttttat ctggtgattc aagatttaca
    27901 acagcagtag aagttagtaa agagagattc aaagatggag aagcagaagc tataatttta
    27961 gttggagaag atgctatagt tgatggatta gcatcagcac cacttgcctc tcaaaaaaat
    28021 gcaccaatat tattatctaa aaaagattca ctaccatcag aaatagaagc tgaaatatta
    28081 agagtacttg gaagtaatct atcttctaag aaaatatata tagtaggtgg agaatctaaa
    28141 gtatcaaaag aaactgaaga aaaactttct aaattaggtg taagtaaagt tgagagagtt
    28201 tctggagaag atagatttga aacttcttta gaaatagcaa aacaattaaa agatacattt
    28261 aagactgctt ttgtagtagg tggaaatgga gaagctgatg ctatgagtat atcagctaga
    28321 gctgctcaat ttggtgctcc aataatagtt acaggtaacg aattagatgc aaatgctgaa
    28381 aaattattaa aaggaaaaga attagaaata gtgggtggag aaaattctgt atcaaaagaa
    28441 gttgaagaca aattagttga tatagattta aataataaag ttgaaagatt agctggagaa
    28501 aatagaaaag atactaatgc taaagtaatc aataaatact atgcaggtgc aactaaagca
    28561 tatgtagcaa aagatggtta tgtaggtgga aatggacaat tagttgatgc acttacagca
    28621 gcaccacttg cagctagttc aaaagctcca atagtattaa ctacagaaga actttctaaa
    28681 tcacaagaag aagtagttga gttaagactt aagaatgcta ctaagttagt acaaataggt
    28741 gaaggaatag ctaaaaacgc tattgaaaaa atagcagaaa aaataaactt atttactaag
    28801 aactaataag atataggaat taatattaaa agtttattta gataatatat gattatacaa
    28861 tgcgttaata tgtaagacat agtgtagata ttataaaata tacaaagaac aagataaaat
    28921 aataaaaata aggtgtctca tttagaatta gattgagata ccttatttta ttttttgatt
    28981 ataaatgttg agaaattcat attgcaaaaa ttattataaa aagatacttc ttataatgat
    29041 taaacatatt actaacataa attattttga acttataact taattaaata aaataaatta
    29101 taatgttttg aatttataga gaataaaaac tttaggtata ttgtttgagt tgtatggata
    29161 actatggtat catatataaa atatggtaac aaaattgtaa cttttgatta aaaataagta
    29221 tgagtactaa taaaaaatat gaaaagtaca ttgggggtag aaaataatat gaagaatagt
    29281 aaaaagatat tagctatagg acttacacta tttttagtaa tggtaaatac tcctatggta
    29341 aatgcgttga catcagttga gcaaataaaa gggaatgaca gatatgagac agcagcaaaa
    29401 atagcagata agcaaaacta caatacagca atactaatca actcagataa tagcttagca
    29461 gatggtctaa gtgcaagtgg tttagctgga gccttaaatg cgcctatttt gatgacaaaa
    29521 caaaatcaga ttccaaacac aactatggaa agattaaaca aagcaaagac tgtgtatata
    29581 ataggctcag aatcaacaat aagtaaaaat gttgagaatc agttactatc caaaaagaag
    29641 gttgtacaaa gaatctttgg tgaaaataga tttgatacaa gtataaaaat agctgaaaaa
    29701 atcaaagaaa ttaagccaat agataaagta attatagcca atggatttac aggagaagca
    29761 gatgcgataa gtgcatcacc agtagctgct agagatggag tacctataat acttacagat
    29821 ggaaatagtg tgggatttga cacgacaggc ttaaagagtt atgcgcttgg ttctagtgaa
    29881 ataataagcg acgaattagt taagagcaca aattctatta gattgggtgg cacagataga
    29941 tttgaaacta ataagatagt tatacaagag ttttataaaa atagtaaaga attttatcta
    30001 agtaaaggct tacaattaac agacgctttg gctgcctcta caatagcaaa aaatgctcct
    30061 gtagttttag ttgaaaatgg cagtaataag agtattttaa gtggtgcaga caaattgact
    30121 gtactaggag gcataaatca gaatgttatc aagcaatgta taaatcaagc ttcaccaaat
    30181 caacaaggtt tatattacaa tccaaatgat agagcattta aagagagaat aaagggtaaa
    30241 gtatatgctc ttacaaagca gtatagaaaa gagaatggag taagagcgtt atctgtagca
    30301 agcagattag agggtctagc aaatgattgg tctaatttaa tggcaaataa gaagacttta
    30361 tctcatacga taaatggaaa aaattcatat tctacttttt tgaaatactt agattggagt
    30421 gagattaaac ctggatatat agcagttcaa ggtgaaaata taattaaata taaaattcca
    30481 gataaacctg tatatacaaa tagagatgca gatgatatag gaaactttat ttttaatgag
    30541 tggaagacaa atccagaaga aggaactaac atgttgcata aagggtatga aataatggga
    30601 tttggtatag ctataacagg agataagaat ctatatgcta cacatgaatt ttatggaaga
    30661 tataaagaat aagaaaatat acacaaaatt atgcttgtaa ggaagctata taaataatta
    30721 aattataatg gaaaataaca tttatattaa taaattaata taaatgttat ttttttataa
    30781 tttaatctaa aaaaattgta ttaaaaagtt taaatatagt ataaaatggg taagaaagta
    30841 gtgaaaatta aatggcaaaa ttagggaaat ctaatgacgc aaaactatag ggattaaagc
    30901 ttttaaagcc atatcagcca gttgctaaaa agagtaaagt ctttttattt tataattaag
    30961 attctctttg agtgtctttt tttattgtct gaaacttata gtatttaaat tcatgaaaaa
    31021 ttagatattt attaagggag gattgttatt tcatgaaaaa agcaatatct tgtgtactag
    31081 cagtatctat gtgtagtgca ccactaaacg tttttgcaga acctatatta gaggggaagc
    31141 taagggcagt tgaaaaatca gttacagaaa agttaagggg gagtcttgaa gtagatttaa
    31201 atttttcact gccaataaaa aatagcgagt cagaaagtat gactaatatg cagttacgat
    31261 taaaagatga tagtaacaat agtggaataa taaagcttgg agaaaaagat tcaggaacag
    31321 taaatgttgg gacagataat atagaatata ctataaaaaa attatctgca agtagaagtg
    31381 aaataaaaaa taaagatgag aatatatcat attataatat tgtatttaat aatttacctg
    31441 ttggaaaata caatgtagaa gtctctggag ctggatttaa gaataaagaa attaaagaca
    31501 ttgatatatc aagttattca caaagagtct tattaagcaa tagagcaagt gtagataata
    31561 aaaataaacc tttaaattat gaattattct taatgggtga tgtaaatgga gacggtaaag
    31621 tagataagag tgattataat aaggttttag agaatataga ttcaaataaa agtgaatttg
    31681 atttaaatag agatggaaag gtagatattg ttgacttaga ttatgtacag aaaaatttag
    31741 gacaaagtga agatgcaaaa agcctagaaa gtatagtatc tactaatcct atagtagata
    31801 caagtaaggt tgaattaaaa ggaaatagtg atgtagatat taatggtaat gtagaaaatt
    31861 tatttagtgg agaaaataat ggagttacaa tatcttcaaa aaatgataaa atatgtgagg
    31921 aaaaaccagc agtaatggat atagctttat cagaagcact taatatggaa gtcatcaata
    31981 taaaagctcc agaaggtact gctccagcaa aaggaatagt tgaagttact gacaaagatg
    32041 gtaatgttca acagattcct tatgaaaaca aagaatatat gaaaaactta aaagatgagg
    32101 agcaacaaga ggaagtaaat aacgaacaag aagaagtaaa tcaagaagaa gtaaataata
    32161 aagatgaaaa tatagaacag attgataata actcaaataa taaagatgaa aatagcgata
    32221 aacaagaagc aaactctaat accaatcaag ataaaaataa tgataaagaa aattcatcaa
    32281 tggataaacc tgatttgggt gaagatactc caaaaaaaga gagtaatatc agtaaagatg
    32341 ataactctac aacatctaca tatagtaggt cagtattaga aacatatgca gatgttcaaa
    32401 atagcgatat agtaataaat cttggtaaac aagtagcagt aaaaaagata actataaaaa
    32461 taacagctac aacagcaaac gatagaaatc ttgcagaaat atcaaaagtt gaatttttaa
    32521 acaatttata taaagaaata ccaaagccag agatgaatat acctaaaata aataaaatat
    32581 caactagcac tgctgttgga aatgaaaaag tatcttttta ttggaataat gaagtaaatg
    32641 tatcagcata cgaacttata ctagataaaa ttgatagtaa gggaaaagta ttatctacta
    32701 aaaaattaca aactagtaaa aatacaatag aagttagaga tatagaagca tatggactat
    32761 atagagttag catacaatct ttaaatggag attggtctag tggttataaa gatgcaacac
    32821 cagaaaactt agatggagta ccagaaaatg tagattcaaa ctataaacct atacaattta
    32881 gcccagatag tatattagaa tttcaagttg ttccagacac aaaaccagaa ccaccagaag
    32941 gtataaatgt taaaggtaaa tttaaatctc ttgatgtaag ctggaaaaat cataaacaag
    33001 ctaaagactt tgacttgtac tataaagaaa aaggctctaa tgggtcttgg ataaaataca
    33061 atgataagct tattcgtggg acaagttcaa agatagaagg tcttaaagat aatacaacat
    33121 atgaagttag aatgacagct actaaccact tgggaactag tggaatgtct aaaacatata
    33181 taggtacaac tgaaagcatg gatgcaccaa caacacctaa ctatagatta attaatactc
    33241 ctaaagagaa tggtggattt ggaataccaa caaatcacat tgtagatgtt acttatccag
    33301 caggatatga caaaagtgaa tatagtgata aaaatccatt tgataaattc aatgtagtag
    33361 atggggactt tacaacacat tggacattcc caacatataa tgcagctgag ggaacgaata
    33421 gaggaccaat aataactttt gataaatctt atactatgga tacttttatg gttacacctc
    33481 gttttgatgt ttctgacaag acaataaatg actttgaggt acgatattgg gatgaaaatg
    33541 gtcaattaca taatctgggg aatgttcctt ttgaaacaaa gacagaccct gtaaataata
    33601 ataagtatgt aatggttaga ttaaaagaac caataactgc taccaagata caagtaagtg
    33661 tttgttcatc ctattcatat aagtctaata tatcagaact taagttttat gagtatgaca
    33721 gtatagaaga tgatgtaaga aatctattta tggatgacct acaagttgaa ttaaaagaag
    33781 atgtaactca agaaaaaata actgaattaa aagatagatt aaatactcca gataaagcta
    33841 gtggagaata tcatccatat aagacagtta ttgatagaga attaaaatta gctcaagact
    33901 tatataatga tagagccaca cttactgatg taacaactgt aaatcaagaa ataaataaat
    33961 caggaaaata taaagataaa aacggacagt atactgtaaa ttccaataat ttaggtatgc
    34021 aaaatgactg gcaggcatta ggagtagctg ctagagcagg agatgaaatc acagtatatg
    34081 ttggaagtaa aagtggaaaa actcctaagt tgatatatac acagtactat ggagaatctg
    34141 gtgcatataa gagtggagaa ataaatctta aaactggaaa aaatgtaatt caattaagca
    34201 aacttcatag tttagatata gaatgtggag gaagtttata cataagatac cctgaagata
    34261 ctccaagtgg aggagatata aaagtacgtg tagcaggagc tactaagata ccacatctta
    34321 atctaaatgg aacaataaat gataagagtc ctgcgggagt ttctgaatct aagaaaaaga
    34381 taaaagcata tatagaagaa ttagctaaat ataaagatgc tgtaaaagga gaaccatatt
    34441 atccaggaac aaatgttggt aattcatatg gatattcaga caaaactggt gtgttaaaca
    34501 ctacagatat tgaaagtgat aaagtaacat taaatgttcc tgcaacagct atatatcaag
    34561 gaatatcaaa aggaaatgct gatttaaata cacaagtaga tagattctat aatagtatgc
    34621 ttgcatggga acaaataatg gatttagttt actcagaaag aggagtattt aaaacacaag
    34681 atttagatgg taatggaact gtagatgata atgaatttaa cttaactaaa aatgatatgg
    34741 ctccaaaatc tcgtatgaac ataaaatacc aaagaatgtt tattggagca tttatgtatg
    34801 cttctggatt acatgtagga gtagaatacg gttcagttcc aggacttatg aatggagtac
    34861 ctttccaaat agatgatagt ggaaaagcta caggaggaaa tttatttgga tggggaatag
    34921 gtcatgaaat aggacatgtt acagatattg gaaagatgac atatagcgaa actagtaaca
    34981 atgtacttgc tttacttgcc cagacatttg atgataagac acattcaaga cttgaaggtt
    35041 caacaatgga taagatatat gaacatgtaa cttcaaatag cttaggtata ccaagcaatg
    35101 tatttgaaag gcttggaatg ttatggcaat tacatctagc ttatgatgat gattttacgg
    35161 gttcaatgtt aaagaataac tcagatgttg atttaagtaa tgacacattc tatgcaaaga
    35221 tttcaagaaa atacagagca ctttcaagca gtgacccaat taatagttta ccaaaagacc
    35281 aaatgctagt agcaatggca tcaagtgttg ttgaaaaaga tttaagagat tactttaagg
    35341 catggggagt agaaattaca ccagaattaa acagtataat ggatagtaag aactacgaaa
    35401 aagaatcaag aaagatacaa tatgtaaatg acgaagctag aagaaagact ttaaatgaaa
    35461 atatagctag tatggcaaaa gatactaaag taagtgctag tttttctgat ggaatacaaa
    35521 gtggttctct agttaaatct agtaaaatat ctatagacct agatgtagat aaggataaag
    35581 ataagatatt aggatacgaa ataataagaa gtgatggaaa ttatttagag ggtgaaaatg
    35641 gaacacaggt aaaatacaga acagttggat ttgtggatgc aaaaggaaat agtaaggcta
    35701 aatttactga taatatatct cctcttaata acagagcatt tacatataag gtagttgcat
    35761 atgattatca cctaaatcca acagaagaat ttgaagttgg tactgtaaaa ttatcagatg
    35821 aagggaaaat aaataaatca gcatggtcat tcataacaaa tactgtttct gatggtgatg
    35881 ttagaactga aaatgactca catgggccat tacaaaatcc tgaaattgat aatataaaag
    35941 ataatgatgc aagtactaca tataaaggaa agataataag taaagcagag tggaacaaag
    36001 accctcaaaa agaccctgat ataaatgtag aagaaaatcc atatataata gtagacatga
    36061 aagaaacatt acctatagta ggactaaaat atacaaaacc aaaaacagaa actagaaagt
    36121 tctcattaaa aggattattt aactttagaa aggatactag cacaacatac aatcctttaa
    36181 ctaattacaa gatacaagta agtaatgata aaaagaactg ggaagatgta agtcaaggaa
    36241 cttttgaata tggacaagat ttagttggtg gaggaaaaga ccaagataat gaagctagag
    36301 ttacatttaa taaagatggt aaactttgga catatcaagc tagatatgta aaactaatct
    36361 caaataataa gtctaatata gaagttgcag aattagatat aataggacct ccaggtgata
    36421 atatagaaat tggcacaatg aataatgcag accagactcg tactaatgga attggaaagt
    36481 tagcagaaga ttatgtatat caaagtgatg accctagcac aagtgaagat gaaacagcta
    36541 agattccagc aggttcaata gttattacag gtgaatacag tggaaatcca gcatttaatt
    36601 taccactact tatagataaa aacaataaga ctatatctgg agaatcgctt ttatttgcag
    36661 aagttccaga aaaaggtgaa ttaggtgaaa tcagtaaagg tacatgggtt tactatatgc
    36721 caaaagaaaa ctttgattct ttaagtgata aggttaaggc tgaactatat agatacaatg
    36781 accttcaagg agatactcca gtaggtcaaa gatttgtaag tgatacaatg tgtgtacctg
    36841 taggagctaa gaattatgat gagttaaaga caataagtct tactgatagt aatagtaaag
    36901 ctagaaaagc tacaagaaat gctattgatg ttagtaataa gaaggttata actgtaagca
    36961 atagagtaaa ggttaatatt gttagagata aatagtaggt ggaactctaa aaaacgtaaa
    37021 aatactaata ctaacattgt atatctaata tgattaggta ttagaatagt tttaaaatag
    37081 tagatattaa aagtaaagta tataaatgta actataagtt tagggtaatt tataaattaa
    37141 atataaaagc taggtggata agtaaattta tccacttagt taatgataga taaggacggg
    37201 tgttaatgag taaaagaaaa tcttttataa gaactatagc agtatcaact atggcagtag
    37261 ctgtaactgg tagtgctaca tgtgcatatg cagctccagt tttacaagga acaaaaacgt
    37321 atgagaaagt aaatactata gatatatctg tggactcagt agaaaacata gtatattcat
    37381 ttcaagccag tataaaagta caaggtgagg ttgaagtagt agataatgag cagaaagaaa
    37441 agattacttg gtctgataat ataaaatctc agataaaaag tggaaatgca aatgctactt
    37501 gtagagcaga atacaacaaa tcaagtaata caactacatt agatatatat gttacatcaa
    37561 atgaagattt attagacgga aatagattga atataggaag aatatctgta aaaaaatctg
    37621 gtagtaactc aaatgctgac tataaagttt taggaaaagg aacaagcgat aaaccagctt
    37681 taaaaattgt aacatataac aacaaaacag tggattatga aaatataaac tctgatgaag
    37741 gattaatatt tacccttatt aatgagagtg aagtaaaacc aattggtgga actggttcta
    37801 gtaaaaatga ccctgaaaag tataaggtag agaaaagtga agcacttgaa tatttattaa
    37861 acaatattag gataaactat tctattgtta gtaaagaaac acaagaaagt ggttcaaatg
    37921 taatattaaa acttggatta gcacaaaaaa caactaaggg aagaaaagct acaataaata
    37981 aatatgttga agttacactt ccaaaaagtt tagaatacat agttgaaaat gaattatcca
    38041 aaccagatga attaccacca gataatggca atggtggaaa taatggtgga ggaagtaatt
    38101 caggcggttc gtctagtggt ggaagctctg gaggaggaaa ttcaagtgat tctacatcta
    38161 atgtcacagt caaaaaatta aaaggtgttg atagatttga gacagctgtc aaaatatctc
    38221 aaagtggttg gacaaaatca gatacagttg taatagtaaa tggagaagat aaaagtatgg
    38281 tggatgggct tacagctaca ccgcttgcta gtgtaaaaaa ctcaccgatt cttttatcat
    38341 caaatgaaaa gcttcctcaa aaaactgtag aagaattgaa aaggctaaat ccatcaaaag
    38401 taattgtgat aggtggaaac aactcaatgc caaattcagt tgttgaagct atcaaagctg
    38461 taaattcaaa aatatcagta caaagaataa gtggagatac aagatatcaa acctctatta
    38521 atatagcaaa agaaatagat aagacgaaca atgtaagcaa gttgtatata ggagcaggaa
    38581 atggagaagc tgattcatta tcaatagcat cactggctgg taaagaaaaa actccaatag
    38641 tacttacaca aaaagatggt gtagataatg aagctgaaca atttattaaa tcaaataagg
    38701 tgtcaaatat atattttatt ggtggagtag aaaaaatatc taacaaggct attgaacaag
    38761 ttggaaaaat agcaaacaaa gatatatcaa acaatagggt ggcaggtcaa actagacaag
    38821 agacgaatgc caaagtaata gataaattct actctcaatc taagctagat ggagttgtag
    38881 ttgcaaatca agacaaactt atagacgctt tagcagttgg accattagca gctaaaaaca
    38941 attcaccagt tatacttgct acaaatacgt tagataaatc acaagaatcg tcattaaaag
    39001 gtaaaaattc atcaaagttg tttgaagtag gtggaggaat agcctcatct gtaatagata
    39061 agattaagag tttaattgaa aaataaatat taagtaaata gaaaataaga atgtatttag
    39121 atataaagtt atatatttaa atgcattctt attttatttt cattatctta acaatttaat
    39181 aatattgagg ttaaaatgta taataatttg agctatatta agtttaattt taaataaagc
    39241 agatatcttt tatatatata aatataaatt caattttgaa tatgtttaaa aagaagttaa
    39301 aaataatttt ttaaatttaa taaaataaaa cactaatata tagacgagat atattcatat
    39361 catatatact ctataatata tggaaaataa agagaaaata aatggaaaat aatcacaata
    39421 taaatataaa atataaaaat catcaggggg atatgaaaat gaacaaaaaa atattatcat
    39481 taggtctagc agtatcatta atcttagtaa acttcaaaag tgtaaatgca tcatcagtag
    39541 tagaaaaaat atacggtaaa gatagatatg aaacagcagc aaagatagct gataaacaga
    39601 cttatgaaac agtaatttta gtaaatacag aaaaatcact tgcagatgga ttaagtgcaa
    39661 gtggattatc gggagctaca aaagctccaa tactatttac acaacaaaat aagataccag
    39721 cagacacaaa tagatgtcta aaaaatatca aaaaagcata tataataggt acagaagata
    39781 ctataagtaa atcagtagaa aaagaactag attctaaaaa tatagaagtc aaaagaattg
    39841 gtggagaaga tagactaaaa acaagctatt taatagctaa agaaatagca actataaaaa
    39901 aagtggataa agtactatta actaatgcat atagtggaga agcagacgca atgagtgtat
    39961 catcagtagc tactagagat ggagctccaa tcatacttac agatggaaag agtgtgcctt
    40021 ttgatgtaaa aaatattcaa tcatattgta taggttcaga ggagataatg agtaatcatc
    40081 tagttaaaaa tacaaactca gtaagaatag aaggaactga ccgatttgaa actaacaaaa
    40141 acgtaataga ctactttttt aatagtgcag atggattcta tgtatcagat ggataccaat
    40201 tagtagatgc aatagcagct gcaccactta ctaaaaactc tccaatggta ctagtaaatg
    40261 atggaagcga taaaactgta ttagaaggag ctaagaatat aacctctgta ggtgaaataa
    40321 atgagaaggt aatacaacag tgtataaatg cttcaaagtc aaatggacaa ccaccaacaa
    40381 ttacagttgg aagtacagag atatataagg gtgaaaagtt tgacactggc aagttaaata
    40441 tagtggctaa agataacaca gggaaggtat taccaataga agttgatggg tttatagata
    40501 caaatagagt aggtacatac atattgacat taaaagctac agacgaatgg ggaaaaagta
    40561 caggaaaaag agtagaaata aaagtgttgg atgacaaatc tcatgattac aacagcccag
    40621 aatttaaaaa aatggtatct actgaaatgt ataacttaat caattcctat agaaaagaaa
    40681 aaggcaaaga gcctttggta gtatctagta agctagaagg tatggcaaat gcatggtcta
    40741 agtatatgat ggataaaaaa gtatttgcac attatataga tggaaaaaat gctccacaag
    40801 tattttctga gtttggaatg agaagtgagg aaaatatagc atatatttat atagattcta
    40861 agaacgttca aactacacaa gatgcaaaag acttggcaaa ggctatattt gaagtgtgga
    40921 agaagtctcc agagtacaat gcaaatatgc ttagtgatga gttttatagt actggatttg
    40981 ggctttatat attatctgat ggtcaagtgc atgctactca ggagttttta aatggcaatg
    41041 aaggtatctt gtaaaaaatt ccataaatct tgtttttttg ttaatttact gatattataa
    41101 aatgaaaatc acatctaaag tactttttgt aatctgtttt gttattgctt tacaggttat
    41161 ggtattttgg gtgttttttg ttttagtagt ttataaattt tgagggaatc actactgagg
    41221 atgtaattta tgattagctg aattatataa aaaaattagt aggaggagtt tgatgaaggt
    41281 aaataagaga gtattatcaa taggattgac aatatcatta ataatggcag gagcaccaaa
    41341 tatcaatgca ctttcgagca tagaaaagat acaagggaaa gatagatatg agacttctgc
    41401 attgatagca gataaacaaa tatatgatac agtcatatta gtaaataccg ataattctat
    41461 agtagatgga ttaagtgcaa gtggattatc tggagttgta aaagctccta taatgttggt
    41521 gcaaagagat aagataccaa cagatgttga aaaaagacta aaggatgtta agaatgctta
    41581 tgttataggt acagaggata caataggtaa atctgtagaa aatcaactta agaataaagg
    41641 gattgaagtt aaaagaattg gtggggaaga tagaataaag actagctatc ttatagctaa
    41701 ggagatttca gctattaaac cagtaaatga tggtgataag gtttttcttg taaatggata
    41761 cacaggtgag gctgatgcaa tgagtgtatc ttctgtagct gctagagatg gagttcctgt
    41821 tatacttact gatggaaaga gtataccatt taaggttgat ggcgttcaat gttattctct
    41881 tggctcagag gagataatga gtaatgaact tgtgagtaag actaattctg ttaggattgc
    41941 tggtaaggat aggtttgaga ctaataagaa ggttatacaa cgcttttata aaggaacaaa
    42001 gaagttttat gtttctcaag ggtataagtt agttgatgct gtggctggtt ctccgttggc
    42061 taaggacaaa cctatagtac ttgttaatga tggaagtgat aagagcgtgc ttagaggtgc
    42121 tgatgaagtt acttctttag gtggaatgga taagaaggtt gttgaccaat gtattagttc
    42181 tgcatctgat aaaaatacaa tgcctacaat cactgctaat gatgtagaaa tttctgtagg
    42241 ggataagttt gataatagta tgttgaatat agttgccact gattattatg gaaataattt
    42301 gaagcctaat attgagggaa ctgtggatac cagtaaggca ggaacgtatg ttttgaatat
    42361 aagtgctttt gataattttg ggcaaaagtg tgagattaat gtaaatgtca aagtaattat
    42421 aaacacaagt acaaaagacc ctaatagtta tgagtttaag gctatggtat ctaatgaaat
    42481 atacaatcta gttaattctt atagagatga aaaaggtaaa aagcctttga aagaattgaa
    42541 atctttgact ggaatggcaa atgcatggtc taagtacatg tatgaaaagg aaatatttgc
    42601 tcatgaaatt aatgggaaaa atgcagctga ggtattttct ggttttggaa tgagaagtgg
    42661 tgaaaatatt gcatatctgc ctatgaatac tcaatctata tatggagaca aagaagcaaa
    42721 agagattgct aattctatct ttgatttatg gaaaaagtct tcaaaatata atgataatct
    42781 attaaaaagt gaattttaca gtttcggatt tggtatgtat gtatcatcaa atagtgaagt
    42841 acatgctaca atggaatttt taaatagtta atttaaaatt gaaacgataa tttaaaaatg
    42901 aaaataattt taaaaaaata aaattttagg gaaaaaagaa gaaaaaagtt ggaaaaaact
    42961 tctaaaaatt ttgtataact tattgaaaat ttattttaga tagtctatca tagagatgtg
    43021 agaaatattt ggattaatat gaacatgaaa ttttaatgta cataataaga gatgtaattt
    43081 aatataatgt tgggaggaat ttttaaatga aaaaaagaaa tttagcaatg gctatggcag
    43141 ctgttactgt agtaggttct gctgctccag tttttgcagc agcttcagat gtaatatcac
    43201 tacaagatgg tacaaatgat aagtatacag tatcaaatac taaagctagt gacttagtaa
    43261 aggatatttt agcagcacaa aacttaacaa caggtgcagt tattttgaac aaagatacaa
    43321 aagttacttt ctatgatgca aatgagaaag attcttcaac tccaactgga gataaaaaag
    43381 tttattcaga acaaacttta actacagcta atggaaatga agattatgta aagacaactt
    43441 taaaaaattt agatgcagga gaatatgcta ttatagattt aacttataat aatgctaaaa
    43501 ctgttgaaat taaagtagta gcagctagtg aaaaaacagt agttgtatct agtgatgcga
    43561 aaaatagtgc aaaagatata gctgaaaaat atgtgtttga agacaaagac ttagaaaatg
    43621 cactaaaaac tataaatgcc tcagatttca gtaaaactga tagttactat caagtagttc
    43681 tttatccaaa aggaaagaga ttacaaggtt tctcaactta tagagctaca aattataatg
    43741 aaggaactgc atatggtaat acaccagtaa tattaactct aaaatctact agtaagagta
    43801 atttaaagac tgcagtagaa gagttacaaa aattgaatgc tagttattct aatactacaa
    43861 ctttagctgg tgatgacaga atacaaacag ctatagagat aagtaaagaa tattacaata
    43921 atgatggcga gaaatcagat cattcagctg atgttaaaga gaatgttaaa aatgttgtat
    43981 tagtaggtgc aaatgcacta gtagatggat tagttgcggc tcctttagca gcagaaaaag
    44041 atgctccact attattaact tcaaaagata aattagattc gtcagtaaaa tctgaaataa
    44101 agagagtttt agacttaaaa acttcaacag aagtaacagg aaaaacagtt tatatagctg
    44161 gtggagttaa tagtgtatct aaagaagttg taacagaatt agaatcaatg ggattaaaag
    44221 ttgaaagatt ctcaggtgat gatagatatg aaacttcttt aaaaatagca gatgaaatag
    44281 gcttagataa tgataaggct tatgtagttg gtggaacagg attagcagat gccatgagta
    44341 tagcttcagt tgcttctact aaattagatg gtaatggtgt tgtagataga acaaatggac
    44401 atgctactcc aatagttgtt gtagatggaa aagctgataa aatatctgat gacttagata
    44461 gtttcttagg aagcgctgat gtagatataa taggtggatt tgcaagtgta tctgaaaaga
    44521 tggaagaagc tatatcagat gctactggta aaggcgttac aagagttaaa ggcgacgata
    44581 gacaagacac taactctgaa gttataaaaa catattatgc taatgatact gaaatagcta
    44641 aagctgcagt tttagataaa gattcaggtg cttcaagtag tgatgcagga gtatttaatt
    44701 tctatgtagc taaagatgga tctacaaaag aagatcaatt agttgatgca ttagcagtag
    44761 gagctgttgc tggatataaa cttgctccag ttgtattagc tactgattct ttatcttctg
    44821 atcaatcggt tgctataagc aaagttgtag gagaaaaata ttctaaagat ttaacacaag
    44881 ttggtcaagg aatagctaat tcagttataa acaaaataaa agatttatta gatatgtaat
    44941 aaattttctt gataaaataa agaactcctt ataaaggagt tcttttattg tgttaaatat
    45001 tcaaaaaagc aaaaaggaga ctagaatagt ctccttttat tgtgagaaat acttaaatat
    45061 aagagatata actatttatt taagtaaact tattatacta tacttaaaaa aaaatgtcta
    45121 cttatccata attttaatgt ataatagtat ttgagaaaca aataaggagg aaaactacaa
    45181 atgacagttt tagatagaat tgtagataag tcagatgaat tagaaattaa agtacttaat
    45241 tatatagttg atgatataga gactttggaa ccaaaaatgg aatctttaag tgatgaagaa
    45301 ctaaaagata tgacaaatat atttaaagat agattaaaac aaggtgaaac tttagatgac
    45361 atattgcaag aagcttttgc agtggttcga gaagtttcta aaagagtact tggaatgcgt
    45421 caatacagag ttcaattaat tgggggtata gtactacatc aaggaaaaat agcagaaatg
    45481 agaactggtg aaggtaaaac actagttggt gttgctccta tatatttaaa tgctctctta
    45541 gggaaaggcg ttcatgtagt tactgtcaac gaatatcttg cacaaagaga taaagaaact
    45601 atgcaaccag tttatgaatt cttagggtta agtgtaggag ttattacgtc tgatttattg
    45661 ccagaagata gaaaaaaaca atataattgt gatataactt atggtacaaa caatgagttt
    45721 ggatttgatt atttaagaga taatatggta actagaaaat ctgaaaaagt tcaaagagag
    45781 ttatattatt ctatagtgga tgaagtagat tcaattttga tagatgaagc aagaactccg
    45841 cttataattg ctggtagtgg aaaagaagac actaagttgt atgaacttgc aaatgctttt
    45901 attaaaactt taaaagataa agattatgag atagataaga aagaaaacac tgtatgtctc
    45961 acacacacag gtctaagtaa agcagagtct ttttttggta tagaaaatat aactaatata
    46021 gataatatag agatttacca tcatacaaac caagcattaa gagcacataa actaatggag
    46081 agagatgttg agtatgttgt taaggatgaa gaaatacaaa tagtagatga atttactggt
    46141 aggatattag atggaagaag atatacagat ggtcttcacc aagctataga agcaaaagaa
    46201 ggggtaaaga ttaaagatga gtctaaaaca ttagcaacag ttacttttca aaatttcttt
    46261 agattatatg aaaagctttc aggaatgaca ggtactgcaa aaacagaaga aagcgaattt
    46321 gaatcaattt ataagttaaa tgttgttcag ataccaacaa ataaacctgt tataagagct
    46381 gatttacaag ataaagtatt taggacagaa gatgcaaagt ataatgcagt tgtagaagaa
    46441 gtaataaaga taaataaaac taagcaacca gtattagtgg gtactgtttc aatagaaaaa
    46501 tcagaaatgc tttcaaaact attaaaaaag cgaggaataa agcatgaagt tctaaatgca
    46561 aaacaacatg ataaagaagc tgaaattata tcaagggctg gaaaattagg ttctgttact
    46621 attgcaacga atatggcagg tagaggaact gatatagctt taggcgcagg agataaaatt
    46681 gaagaaaaaa aagtaagaga tattggtgga ttatatgtta taggtactga aagacatgaa
    46741 tcaagaagaa tagataatca acttagaggt cgttctggac gtcaaggaga cccagggaca
    46801 tctagattct ttgttagttt agaagatgaa atgataaagt tatatggtgg aaaaggaatt
    46861 gaaaagattt taaaaaggat gaatgctaaa gatgaagatg caattgagag taaatcatta
    46921 tctaaagcca tagaaagagc tcaaagagga atagaaggta agaattttga gcaaagaaaa
    46981 aatgtactta aatatgatga tactattaat gagcaaagaa aagttatata tgaggaaaga
    47041 aatagagttt taaatgattt aaatatatct gaagatatac aaaaaatggt tagagaaata
    47101 atagaagatg cagctaataa atatttatct aatcaaagag attattatgg ttactttaaa
    47161 tctctgtaca atgattttat gcctccaaat acattgttga ttccaggggt agataaaaaa
    47221 agtgtagatg aagttgtaca acacacatat gaaatatcca aaagagttta tgatattaaa
    47281 aaaatggaag ttggtataga caaaatagaa gaattagaaa agagagtttt attgcaagta
    47341 gttgatactt attggatgga ccatatagat gccatggatc aactaagaca atatataggt
    47401 cttaagtcat atgcacaaaa agatccattt aaggagtatg ctttagaagg atatgatatg
    47461 tttgaagaac taaatagaaa aataagaaca acaacagttc aatatttata caagtttgat
    47521 taattaagaa cacaattcaa aatagttttt agaattattt tgaattgtat caagtaataa
    47581 tataggatct aattatttaa cttagaaaaa agaagctata tttaaaataa taattatttt
    47641 aaaatatagc ttctttttgt gtgagaaata cggaaaaaag agatgattga aatttctttc
    47701 ttccttttaa tattatacta taaagagtat taaaagtcta ttagttataa gtggtaaaat
    47761 taaataaaat tacaaaattg ttacttttat gtatacataa atatatgcca atattttaca
    47821 tggaaaaaaa tgattaattt ttgtataatg aaataaagat tctaataaag ccagagttat
    47881 catatacatt gaaataatat tatatttgta ttataattta tagataataa gtaattttaa
    47941 aaatagaaat atacataatt catatatcta aacaaagttt atctatgcta tgcaatatca
    48001 aatattttaa tgttgtgtat gatgattcta gagtcttgaa atttttataa ttacaattta
    48061 tattgacact taagttgttt aataagtaag agcattaaat gaaatatatt agaaattgag
    48121 gggagtacaa gttatgaata taccaaaaaa aattatatcg ttattgacaa taacaataat
    48181 gttaagcgga ttatctttaa atacagtaaa tgcttcaaca aaagaatctt tagttggtag
    48241 tggaagatgg gagactgcta tacaaataag taaaaatggt tgggaaaatt caaaagaagc
    48301 agtattagtc aatgatagtt caatagcaga tgcattatca gcaacaccat tcgcaaaagc
    48361 taaaaatgct ccaattttat taacacaaag taatagtctg gatgcaagga ctaaagctga
    48421 attaaaaaga ttaaatgtat caaaggtcta tttaatagga ggaaatgtta cactaagttc
    48481 taatttagag tatgagttga aaagtataaa tattaactca gaaagaatat ctggagatag
    48541 tagatattct acttcgttag aattagctaa aaagatagat agtataaaca ctatttctaa
    48601 aattgttgtt gtaaatggtc aaaaaggttt agctgatgct gtaagtgttg gagctgcagc
    48661 agctcaagga aatatgccta taatactttc agatactact aatggaacta gcacttcaaa
    48721 agattttata agtaaacata atataacgac atcttatgta attggtggta ctaattctgt
    48781 atctgaggac attaaaaatt cgcttcctaa tgctaaaaga atttctggag aaaatagaaa
    48841 ccaaactaat gcaaaagttg tagaagaatt ttacaagggt acaaatttaa aaaatttata
    48901 tataactaaa gatggtatga aaaaacaggg tgacttaatt gattcgctag ctgttggtgt
    48961 tttagctgct aaaaatagtt cacctgttct tttggcagga aataaattgg actcagttca
    49021 aaaggatata ctagatacca aaatttttga taagattaca caagttggtg gaaatggaaa
    49081 tgaagatgtt tttaagtcaa tacaagatat tcaagaagaa actaagtaca cagttgaaac
    49141 aatttctgaa cttgatacag ctataaaaaa atcagatgct aatgatatta taagatttaa
    49201 aaatgatgat aaaataactg gctcaattga tataagtaca aaaaaagcta taacaattga
    49261 attcaatgga ttatatagtg gaaaagtaaa tataaatata ccaaatggag atgtatataa
    49321 ttatggagat atgactggcc agatggatat taaagatata aaaactgaca ctttagtaaa
    49381 tgaagggtca attaatgaga taactatata tgacccaaat ggttgtaaaa tagaaaatga
    49441 aaaagatgct gatatttgga aaataacatt actggataca tctaagaata cctatataaa
    49501 taatagtgga actataacta aaatagttag tgatgcatca aatacaacta taaaaaattc
    49561 aggaaagatt gagttaataa gtgggactaa gtctccagca gtaagtggta atcaagccac
    49621 tgatgaaaat ataaaagata atgatgacaa agaagcagga ggaatttctg tatatgtaga
    49681 tccatgttct cctccaaaag aaggaaaggt aatgttaaga ataccaaaag aaccaagaag
    49741 ttctagttat aacatatact acagaattgt taaatctaga ccatctgcaa tggatgtagg
    49801 agatactata tcaaaaaggg gttggactaa agtgactact agagattcat ttatgattag
    49861 tgcgacagat ggatattatg tagaagctgt agaaatctat gattctgata gaaaggtaag
    49921 taagtgggga agatcaggaa gtatagatga tggatataac aatacaactt catcagcaac
    49981 attaagaagt tataaataaa atattgatat gcatataaat taagaaggat tttttgtggt
    50041 tgttagtttc tatgtattta tgatataaat aatttaaaaa tgagttatat aaacttgtta
    50101 cattaattaa ttttaattat tgtgaagtta ttatatagct tatttttatg aaaaagttta
    50161 atgtacaatt taaggtgagt atactacttt tgatataaaa cttttaaaat tattattcaa
    50221 taaagtttta ataatttcaa aagtagtgta tactcatttt atgaagaatt ttaatgaaat
    50281 aagaataaat aaggaggaaa gagtaagttg aatataacta ataaatgtgt tttaggaata
    50341 tctattttag ctattttgag ttttggattt tcagcgtttc aaggtaatgc tcaaattact
    50401 gatagaaaaa aagattatga tatatatcta aaagcgaact ctgataaaag tgatgtaaaa
    50461 tcgtctttaa atgatatttc taagttagag aaaaaatatg gagaaagtga tgcgttgagt
    50521 atatctaaga ttaatttata tgaaaagatg aatgattata aaaatttaca atctgaaatt
    50581 gagaaagttt acaatagata tcctcaaact agaaatacag tttcatttgt acttttatat
    50641 tctgaagttg ctttaaaaaa tggaaacaaa gaattgtcaa agaatatgat taatgaagca
    50701 attaaattag gagcacaaga tgcttataaa gaaagagtgg ataaggtatt atcacaatta
    50761 aattaaaagg agaaatatat gttagataaa tattacaata gaggaaaagt tgaacaaata
    50821 gataaattta ttttgtttat attattattt atgatgtgta ttattccaat aataactcat
    50881 gaatatactt ctacaaacta tagtcctatt tttacattaa cattgtattc ttcaggagaa
    50941 agggtagaaa tatttaattt ttataaaaca gcaatattgt atttggggac aatgatagtt
    51001 ttttgttttt ttatgtataa aatttttgta cttaaagaag aattaaaaaa aagaaaagtt
    51061 aatataatat tgcttatctt agcaatagga gtaatattat cgtctgtttt ttctgattat
    51121 aaagatatcg ctttatttgg aaatcctgat agatttgaag gagctttggc ttggttttgc
    51181 tatatagtta tattttttgt gttgtataat attaagatag atgtaaaaga tttgaaatta
    51241 ttttattttg gattgtttcc ttttttagtt ataaatttat tcttaggatt agctcaattt
    51301 tttgaaattg atgttttaca atctaaaatt ttaactactc ttattggtgg aggaacttta
    51361 tctggaacat tttggacaac tttataccat tttaatatca tgagtgggat agcatctgtc
    51421 attttttgtg ctagcttagt atatatgtta tttgaaaaag atattaagaa aaaaatagta
    51481 ccattatttg gagcaattat gtcatttaca ataattctta tatcgaattc tataagtggt
    51541 tttttaacat ctatattatt attcccaatt atattagttt tatcttggag atttgtgaat
    51601 aaaaaagaat tatgtgtatg gacaattatt atggttataa ttagttccat tatatatatt
    51661 atattaaata gacataaccc aaatgtttat caagaaacat ttgctatgtt tgaaaaatta
    51721 aaccaagcat caatatttat agttcctata ttgatagtaa catttatatt gttgattatt
    51781 ataatgaaat ttataaataa aaagaaattt tttaattttg ttactgtatg ttctattgtt
    51841 atagtctcag ctggattatt atttttttca tatacactaa ataaagaagt cagtatttta
    51901 gaaagcaatc caaatgctaa tattactaga atagaagatt ctaaattatt taatataata
    51961 aatggtatga gtacagatcg tttaaacata tggactaaag ttatgaattt tataaatgaa
    52021 agacctatat tgggaaatgg atttgatact tttccatata aattcattag tacagataaa
    52081 aatggtgctt taagtacata tggagaggtt atagataaac cacatagctg gtatatgagt
    52141 gttgcatatg gaagtggtat aattggtata attggtttag tgggtataat aatatattta
    52201 actaaagaag ttttctatag ttgtgtggat aaaaataatg ataaatttct atatatattt
    52261 tttattggct ttttagcata ttctattcaa gggttattta atgatagcct tgcaggatct
    52321 tcaataataa gttgggtttt tgctggttta actgctaata gaatatttac aataaagtct
    52381 aaataaattt taaaaatggc atagtggact aattatagaa aactatgtca ttttatttta
    52441 aaaaaataga tattattttt agttagtatt ttaatctatc tacaaataat ataaaataat
    52501 agatgtatgt ttataattta aaaaaaatca aaatctaaag taaaatgtgt agaatcatta
    52561 aataaatcaa aaggggatga tagtttgaat gtgagtataa taataccaac taagaatgca
    52621 gaaaagtata tagagaatct tataaaagca ctaataaatc aaactataga accttgtgag
    52681 ataatagtta tagatactga atcgaaagat aaaactgtag aaatttgtat ggaatacgat
    52741 attgtcaaat ttatacaaat aaaacaaagt gaatttggtc atggttcaac tagaaataga
    52801 gctgctaaat taagtaaagg tgatattcta gtttttatga cacaagatgc tttgccacaa
    52861 aattgttatt ttatagagga actaataaaa cctttaggta aaaataatat tgtatgtact
    52921 tatggaagac aattgccaag aaataatgca aaaacactag aagtattttc tagaagcttt
    52981 aattatggaa atagtgatat aataaaatct aaagaagata ttcctaaact tggagtaaag
    53041 acttttttct ttagtaatgt ttgttcttct tttataaaaa gagacttttt tttggttgat
    53101 ggatttccag aaaatataat aatgaatgaa gatatgataa tatcttctaa gattatatat
    53161 aatggtaaaa aaacttgtta tgcatctaag gctattgtta cacattcaca tagatataca
    53221 tacttacaac aatttaaaag aaacttcgat ataggtgttg catttaaaga aaatagttat
    53281 tatttaagtg aagtaaagtc tgagtcagag gggtttaagt ttgtcataga agccattaag
    53341 tttttatttc aaagtaataa atgttatttg attcctagct tgttcataga aagtggattt
    53401 aaattttttg gatataaatt tggtatgaat tataaaaata tgcctataaa attagttaaa
    53461 ttgatgagca tgcattcttt ttattttgat agaaaagaag ttatggagga gtattatagt
    53521 gaaaatagta ataacaggtg ctaagggaca attaggttta gagatagtaa atcaattgga
    53581 taatttgaat aatataagag aaaaaaatat atatgatata gttccaacag atagaagtaa
    53641 cttaaatatt actgacctag aaaatgttaa taattttatt tttaaagaga tgccagatgt
    53701 cgttataaat tgtgctgctt ataccaaggt agatttatgt gaaaatgata tagataatgc
    53761 atacaaagta aatgccttag gtgttagaaa tttggctaca gcctgtgaaa aaataaaagc
    53821 taaatttgtt caaatatcta ctgattatgt atttgatgga aatagcaata taccttataa
    53881 ggaagactgt attacttttc caaattctat atatggaaag agtaaattaa tgggtgagta
    53941 ttttacaaga caattttctt caaaatattt tataattaga acagcttggt tatatggaga
    54001 tggtgataac tttgttagaa ccatgcttaa tttagcaaaa aataataatg aaattaatgt
    54061 tgttgatgat cagattggaa gtccaactag tactgttgaa ttagctgaag ctataattaa
    54121 tttgattgaa acagattatt atggaatata ccatggtacc tgtgaaggtg aatgtagttg
    54181 gtatgaattt gccaacaaaa tatttgagtt aagtaaaatt actgttaaag ttaatccaat
    54241 aacaagtaat gaattcaaaa gagaagcacc tagaccaatg tattcagttt tagataattt
    54301 tatgttaaaa ttaattggat taaataattt taatagatgg gatgaagctt taaaaaagta
    54361 tttagaataa aaaataaatt tgtttggagg ataaattatg aaaggaattg tgctagcagg
    54421 cggatctggg actaggttat atcctataac taaatgtgtg tctaaacaag tactaccaat
    54481 atatgataag ccaatgattt attatcccat atcagtgctt atgctttcag gtataagaga
    54541 tatactaata atttctactg tcagagatat aaaaattttt aaagaattgt ttggagatgg
    54601 atctcaatta ggagttaata tacaatacgc tattcaagaa aaaccaaatg gtattgcaga
    54661 agcatttatt ataggagagg acttcattgg agatgataaa gtagctcttg ttttaggaga
    54721 taatatattt tatggttatg gatttagtga acgattagag agagctatta atagagatga
    54781 agctactata tttggatatc atgtaagtga cccgacatct tttggtgtag tagaatttga
    54841 caaagatttt aatgtactat caatagagga gaaacctaaa atacctaagt ctaactatgc
    54901 tgttccaggt ctttactttt atgataatga agttataaag attgctaaga gtataaaacc
    54961 ttctaaaaga ggagaattag aaataacttc tgtaaataat gagtatttaa aaaagggaaa
    55021 gcttaaagta gaactttttg gacgtggtat ggcttggcta gatactggca cacatagagg
    55081 gctattagat gcatctaatt atgtagaagt tgttcaaaca agacaagggt tatatattgc
    55141 ttgtttagaa gaaattgctt atattaaggg atatataaca aaagaagatt tactagaact
    55201 tgctaagcca ttaatgaaaa ccgattatgg taaatatttg ataaaaatag ctaatgaatt
    55261 taaagaaaat aaatgaaaat aagataatta ttaaaactgt atgaatacta taatataaaa
    55321 atgacaactt agtttatata atatttgatt gtataaatta agttaaatta tgtactaaat
    55381 atttaaacaa taagaaggtg taattttgaa tattaaaaaa aaatttaaaa tttgtattct
    55441 acttatactt gtatgtatgt tatttttagg agcttggtct aaaatgaatt cttggagaga
    55501 cacattatat acacctacat caatagaaaa aatagatgat ttatatttca tagtagattg
    55561 ttggcaacac cgtgttatat ataatgacaa tcttagtgac aaaatatcta actggaagac
    55621 tttaagtgac aatttagaag gtcctcattc tattgcaagt gataaagaag tatttctggt
    55681 agataataca gaaaagaatg aaatccaagt ttttaaaaga aaagaagata attttatatt
    55741 aactcaaact attcaaaatg ttgggaaaag accacataaa atcatatatg ataagaatac
    55801 aaatttattt tacagtattg ctagtacctc acaagatata gtagttcttg aaaatatcaa
    55861 tgggaatgta agagttaaac aaaaaactag gttagatttt cttgatggat cttacataag
    55921 gtcaatttct attattgaag ataaaatgta ttttttacca ggtcctaata aggtgatttg
    55981 tacagactat aaaagtggaa aatttaatgt gatttctgaa tataagcttc caaaagcttt
    56041 agaagcaata aatcatcttt ataaaataga taattattat tacatatcac tttacacaat
    56101 gggtgaaaat cctaatgaac ctaaattagt tagatttaaa aattttaatg aacttcaaaa
    56161 taatgaatat gaagatctta caaaaaaact aaatattaaa ggagtacctt actttttttc
    56221 agagtttgat gggaaagtat tttttacaga aatagactct tattcagaga ttaaatcatt
    56281 taaagtaaat aatgataata tagatagtat tgtgaattat tatgattcag gcaaaccatc
    56341 aaaagaatct attgaaagaa agaaaagtat tttaagatag atatcaatga ttaaatatta
    56401 ttgtataata aaggagaaat actatgagta agtttaattt tatagaaaca aaattaaaag
    56461 atttgtatat aatagaacct acaatatttg gagatagtag aggatatttt atggaaacct
    56521 acaataaaag agagttttta gaggctggac ttgatatgga gtttgttcag gaaaatgaat
    56581 ctaaatctaa aaaaggtgtt ttaagaggat tacattttca aactgaaaat gttcaaggaa
    56641 aactagttag agtagctttt ggagaagtgt atgatgtagc tgttgattta agaattggtt
    56701 ctccaactta tggactatgg gaaggtgtta tactatcatc agaaaataaa agacaatttt
    56761 atgtaccaga aggttttgca catggatttt tagtactatc taacgaagct gtctttaatt
    56821 atatgtgtac taattattat aatgctgatt atgaaggtgg catattatgg aatgataaag
    56881 atataaatat agaatggcct ttagataaag tagacagcgt tatattatct gaaaaagata
    56941 aaaaactatt aaagttaagt gaattagatt tacaatttaa atatggaggt gagtagaaaa
    57001 tgagtaaagt tttaattact ggaggcgcgg gatttattgg tggaaatttt gttcattata
    57061 tcttagataa atatcctaaa tatgaagttg taaatttgga tttgttaact tatgctggta
    57121 acttagaaac attagaaaat ataaaacata aacataatta taaatttgta aagggtgata
    57181 tttcaaatag gaattttata tttgatttat ttgatgaaga aagatttgat atagtcataa
    57241 attttgcggc tgaatcacat gtggataggt ctatcaaaga accgtggaaa ttcattaata
    57301 caaatgttat tggaacacaa gtactgctag atgcttctaa taaatatggt gtaaatagat
    57361 ttcatcaaat ttccactgat gaagtttatg gagatttgcc acttgataga ttggatttac
    57421 tttttactga aaaaactaac ttaaatccaa gttcaccata ttctgcttct aaagcatcag
    57481 cagatttatt gactatttca tattataaga catatggatt acctgttact atatcaagat
    57541 gttcaaataa ttatggacca tatcattttc ctgaaaaact aatacctctc gtaattcata
    57601 gagcattaga gaataaagag ttacctattt atggagatgg aaaaaatgta agagactggt
    57661 tgcatgtata tgatcattgt acagcaattg atttaatagt tcataaaggt aaaagtggaa
    57721 atatttataa tgtaggtgga cacaatgaaa ggtctaattt agaagtagtt aaaactattt
    57781 tagatacttt aggtaaatct gaagatttaa tatctttcgt tgcagataga aaagggcatg
    57841 atttaagata tgctatagat gcaagtaaat tagagcaaga attaggatgg aaaagtatat
    57901 atagttttga tgaaggtata aaacatacaa taaagtggta tttagaaaat caggaatgga
    57961 tggaaagcat aatatctgga gagtataaaa attattatag taatatgtat aaaaacgaat
    58021 aatattgatt ggagaaatta aaatgtcatt agtaaaagaa ttatatagga atagagacct
    58081 gatattaaac ttatctaaaa atgattttaa aactaagtat gcaggttcat atcttggaat
    58141 attttgggca tttgtacaac cagtagttat agttcttata tattggtttg tttttcaagt
    58201 tggttttaaa gcggcacctg taaaagattt tcctttcata ttatggttaa ttgcaggaat
    58261 agtcccttgg ttcttttttc aagaagcact cataaattcc acaaatagtt tgcttgagta
    58321 tagttatttg gttaaaaaag ttgtatttaa aataagtata ctaccattag taaaaatcat
    58381 atctgcttta tatgtacaca tattttttat ttgttttgca ctagcttctt attgcatata
    58441 tggtatatat ccaaatatct atataattca aatat
//
LOCUS       DAFAZV010000024        56526 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFAZV010000024 DAFAZV010000000
VERSION     DAFAZV010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56526
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.024"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..166
                     /locus_tag="KOU88_002097"
     rRNA            <1..166
                     /locus_tag="KOU88_002097"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            294..410
                     /gene="rrf"
                     /locus_tag="KOU88_002098"
     rRNA            294..410
                     /gene="rrf"
                     /locus_tag="KOU88_002098"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            418..492
                     /locus_tag="KOU88_002099"
     tRNA            418..492
                     /locus_tag="KOU88_002099"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Asn,seq:gtt)
     gene            498..583
                     /locus_tag="KOU88_002100"
     tRNA            498..583
                     /locus_tag="KOU88_002100"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:532..534,aa:Leu,seq:taa)
     gene            599..674
                     /locus_tag="KOU88_002101"
     tRNA            599..674
                     /locus_tag="KOU88_002101"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:632..634,aa:Met,seq:cat)
     gene            682..756
                     /locus_tag="KOU88_002102"
     tRNA            682..756
                     /locus_tag="KOU88_002102"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:715..717,aa:Glu,seq:ttc)
     gene            771..844
                     /locus_tag="KOU88_002103"
     tRNA            771..844
                     /locus_tag="KOU88_002103"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:803..805,aa:Gly,seq:tcc)
     gene            850..925
                     /locus_tag="KOU88_002104"
     tRNA            850..925
                     /locus_tag="KOU88_002104"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:883..885,aa:Val,seq:tac)
     gene            931..1007
                     /locus_tag="KOU88_002105"
     tRNA            931..1007
                     /locus_tag="KOU88_002105"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:965..967,aa:Asp,seq:gtc)
     gene            1018..1092
                     /locus_tag="KOU88_002106"
     tRNA            1018..1092
                     /locus_tag="KOU88_002106"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1050..1052,aa:Gly,seq:gcc)
     gene            1102..1175
                     /locus_tag="KOU88_002107"
     tRNA            1102..1175
                     /locus_tag="KOU88_002107"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1136..1138,aa:Arg,seq:tct)
     gene            2159..2998
                     /locus_tag="KOU88_002108"
     CDS             2159..2998
                     /locus_tag="KOU88_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBK3211986.1"
                     /translation="MLDINSFLNGFFNIILRMSIYDLIDISIVAYIFYKIFMFIKDTR
                     AEQVFKGIIFLLLATQLSNTFKLHTVYWISLKALDYGVIAALIIFQPEFRAGLEHIGR
                     AKFNLFGKNVNTSEETLNRNIEEIVEALYSLSRQKIGALIIMERETRISDIINTGTII
                     DAEISRQLLINIFIPNTPLHDGAVVIRDSKVKAAACFLPLTESKDLSKDLGTRHRAGI
                     GVSEVSDCITLIVSEETGGVSIAKAGKLYRDISRERMMNILRSNLKTNTETRSFFKGG
                     IFK"
     gene            2995..4176
                     /locus_tag="KOU88_002109"
     CDS             2995..4176
                     /locus_tag="KOU88_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3211987.1"
                     /translation="MINRLKNNTKIKIISFLSAIALWMYVMAVVDPEETKGFEDIPVS
                     ISNMSDLKDKNLVIYPDEKLTADVYIKGSLSKVQSVKKEDIHVYGTIEDPIQGQKEVY
                     LKANIPQGVTLEFKHDVLVVNLEKNIKEKRDIKVEVSGNSKRNINKIELSKEFVDVSG
                     PRTLVKEVKSVRANLDVGNETDDFSKKLQLIPLNSDGTKVEGVTLSSSFVTAKIELLK
                     EKIVPIRVSLNDNKDNDVLKNYKLSKEQVTIKGKKEDIDKISYIKTKPIDLADLANGE
                     EKEVSLEIPEGITLEDSSITIKLNDTKQLSAEFLYNAGDIELRNIPTNMDNPNVISDV
                     DIKVVVESTEDLSKLNKKDISLYIDLSQGPEEDSKYKIKYETTYQFKKINIEPNIVEV
                     E"
     gene            4480..5382
                     /gene="ptb"
                     /locus_tag="KOU88_002110"
     CDS             4480..5382
                     /gene="ptb"
                     /locus_tag="KOU88_002110"
                     /EC_number="2.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate butyryltransferase"
                     /protein_id="HBK3211988.1"
                     /translation="MRSFEEVIKFAKERGPKTISVACCQDKEVLMAVEMARKEKIANA
                     ILVGDIEKTKEIAKSIDMDIENYELIDIKDLAEASLKSVELVSQGKADMVMKGLVDTS
                     IILKAVLNKEVGLRTGNVLSHVAVFDVEGYDRLFFVTDAAMNLAPDTNTKKQIIENAC
                     TVAHSLDISEPKVAAICAKEKVNPKMKDTVEAKELEEMYERGEIKGCMVGGPFAIDNA
                     VSLEAAKHKGINHPVAGRADILLAPDIEGGNILYKALVFFSKSKNAGVIVGAKAPIIL
                     TSRADSEETKLNSIALGVLMAAKA"
     gene            5404..6483
                     /gene="buk"
                     /locus_tag="KOU88_002111"
     CDS             5404..6483
                     /gene="buk"
                     /locus_tag="KOU88_002111"
                     /EC_number="2.7.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="butyrate kinase"
                     /protein_id="HBK3211989.1"
                     /translation="MSKIFKILTINPGSTSTKIAVFDNEDLVFEKTLRHSSEEIGKYE
                     KVSDQFEFRKQVIEEALKEGGVKTSELDAVVGRGGLLKPIKGGTYSVSAAMIEDLKVG
                     VLGEHASNLGGIIAKQIGEEVNVPSYIVDPVVVDELEDVARISGMPEISRASVVHALN
                     QKAIARRYAREINKKYEDINLIVAHMGGGVSVGAHKNGKIVDVANALDGEGPFSPERS
                     GGLPVGALVKMCFSGKYTQDEIKKKIKGNGGLVAYLNTNDAREVEERIEAGDEKAKLV
                     YEAMAYQISKEIGASAAVLKGDVKAILLTGGIAYSKMFTEMIADRVKFIADVKVYPGE
                     DEMIALAQGGLRVLTGEEEAQVYDN"
     gene            6473..7150
                     /locus_tag="KOU88_002112"
     CDS             6473..7150
                     /locus_tag="KOU88_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3211990.1"
                     /translation="MITNDKRIRIITGHYGSGKSEFAMNYVVKLRDMVSGKVAIADLD
                     VVNVYFRTREKKELMKSLGIQPIDSSINAPTLDLPAVSAEVMSPMVDHSYNSVIDLGG
                     DNVGARVIGRFSHLLKEGDYDMLFVINANREKTQTSEEVIQYIKEIEKSSKLKVTGLI
                     NNTHLIRFTTIDDVLRGQKVAKEVSEKCNIPIRYVACLENLVEQLPKDLEGEIFPIKL
                     YMREDWM"
     gene            7193..7408
                     /locus_tag="KOU88_002113"
     CDS             7193..7408
                     /locus_tag="KOU88_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3211991.1"
                     /translation="MAKGKVSFNQERCKGCGLCVEACPVKIIQLDSNVINKKGYNPAT
                     VFEMEKCIGCASCATMCPDVVITVERD"
     gene            7437..8516
                     /locus_tag="KOU88_002114"
     CDS             7437..8516
                     /locus_tag="KOU88_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBK3211992.1"
                     /translation="MAKILMKGNEAFGKAAIEAGCKYFFGYPITPQSELPEYLSRELP
                     KIGGAFVQAESEVSAINMVYGGAGAGARVMTSSSSPGVALKQEGITYAVGAEVPCVVL
                     NVMRGGPGLGSIQPSQADYFMSTRGGGNGDYRTPVFAPATVQEAVDMIMEAFDVADYY
                     RSPVMVVADGMIGQMMEPVEFRAPEKKRELPPKDWATVGTKGKRKPNVINSLYLEPEV
                     LEDHCWHLQEKFDAMEKNEVQYEMYKTEDAEFVFAAYGTTSRVVKSAIDILREEGIKA
                     GLIRPKVLWPFPFEAFNQIPNARNILTVEMSMGQMVEDVKMAVEGKLPVYFHGRPGGM
                     TPTPAEIVEKAKKIIAGELVAGGAR"
     gene            8516..9268
                     /locus_tag="KOU88_002115"
     CDS             8516..9268
                     /locus_tag="KOU88_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBK3211993.1"
                     /translation="MAVVFKKTEGLQDTQTHYCPGCTHGIIHRLVGEVLEELGVLGDA
                     VGVVPVGCSVLGYKYFNCDTQEAAHGRAPAAATGIKRVHPENTVFTYQGDGDLASIGT
                     AEIVHAAARGEKITTIFVNNTTYGMTGGQMAPTTLVGQRATTAQSGRNAETQGYPIRV
                     SEMLATLTGAVFVERVAVDTPAHVRQAKKAIKKAFQVQQAGLGFGIVEVLSTCPTNWG
                     LAPNDALQWLRDNMIPYYPLGNFKNVEVEEVK"
     gene            9269..9826
                     /locus_tag="KOU88_002116"
     CDS             9269..9826
                     /locus_tag="KOU88_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBK3211994.1"
                     /translation="MSTARVICAGFGGQGVMSMGQLLTYAGMLEGKEVSWLPSYGPEM
                     RGGTANCAVTVSNEPVGSPLITDDATAAILLNIPAFEKFKDDVIPGGKIIVNSSLIKE
                     KVDRTDVDVYYIPANELAAELGNDKVANMIMLGAYLKVSDTVDIESVLEAFKKVFGPR
                     KEKFVPLNREALQKGMDATCSKATN"
     gene            9996..11342
                     /locus_tag="KOU88_002117"
     CDS             9996..11342
                     /locus_tag="KOU88_002117"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBK3211995.1"
                     /translation="MRKYFGTDGVRGVANTELTCDLAYKLGRAGGFVLAQGDHRVKVV
                     VGKDTRISGDMLEASLIAGLMSVGCDVITVGIIPTPAVAYLTRKYGADCGVVISASHN
                     PVEYNGIKFFNKNGYKLDDEIELKIEEYIDDIDKIDCLPIGENVGRKLHEHCAQRDYV
                     DYLKSIISTDFKGLKVVLDCANGASYKVAPIVFDELGASVISINSLPDGNNINYKCGS
                     THPEQLQRAVLEHNADLGLAYDGDADRLIAVNEKGQIVDGDHIMILSALNLKKNNKLA
                     QDTLVVTVMSNIGLTIAAKENGINLSTTAVGDRYVLEDMVKNGYNLGGEQSGHMIFLD
                     YNTTGDGVLSSLILANIILQEKKPLSEIASIMSQYPQVLVNATIKNENKNKYMEYPEI
                     KTEIERIESILDGNGRVLIRPSGTEPLVRVMLEGKEEGQIKELATDLANLIQEKLS"
     gene            11609..13441
                     /gene="glmS"
                     /locus_tag="KOU88_002118"
     CDS             11609..13441
                     /gene="glmS"
                     /locus_tag="KOU88_002118"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003401499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBK3211996.1"
                     /translation="MCGIVGYLGSRKAAEVIVEGLSKLEYRGYDSAGVAVNSSNEKEL
                     NIRKFKGRLSVLAEDLEKNPIDGNLGIGHTRWATHGEPSDVNSHPHFNQAKTIAVVHN
                     GIIENYMEIKEELISEGVKFESQTDTEVIAHLVDKYYEGNLLDAVYKTISKLRGAYAL
                     GVICKEHGNELVAVRKDSPLVVGVGEGENFIASDIPALLKYTRDVYFLENGEVVHLKD
                     ENVTVYDSNRNLVEKEVFHVTWDVEAASKGGYDYFMSKEIHEQPTGVRETLERRLDDN
                     GNIILDSINISKEDLEKINKVYIVACGTAYNAGLLGKYAIEKFVNIPVITDIASEFRY
                     SDPFVDENSLVILVSQSGETADTLAVLRDSKAKGARILSITNVVGSSIARESDDVFYT
                     WAGPEVAVASTKAYTTQITSLYMIALDFAIKKGTITREFYDSMISKMKEIPSKIQEIL
                     DNEEYIKEVAKTVVSSEHAFYLGRGIDYSLAMEGSLKLKEISYIHAEAFAAGELKHGT
                     IALIEKGTPVIAIATQEKLFEKMVSNMEEVRARGAYVVAIAQSHNKDVEKAADKIIYI
                     PNSDDILSPILAVVPMQLLAYHVSVLRGCDVDKPRNLAKSVTVE"
     gene            13893..15188
                     /locus_tag="KOU88_002119"
     CDS             13893..15188
                     /locus_tag="KOU88_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase"
                     /protein_id="HBK3211997.1"
                     /translation="MTNDFKKEKKEDYFVNLKAISTEVLQEKVQDNAWVIVDTRLNDA
                     YNGWKLDGVKRGGHIKGAVDFSANWLSVYLDRKDEVLEQALKTKRIDLDKNIVLYDAN
                     GKDALVVADYLSKKGYKYLYKYDIKQWADDENLPMERYKNYQMIVPAFIIKDILDGKI
                     PETFEDSKNIKMIEASWGEESYTKGHIPTSVHVNTDIIEPPPTWMLDNDDNLTKFALD
                     YGLTKDDTVIVSSSTPMASYRLAVILRYIGVKDVRVLNGGTNSWLSAGYELEFISNPK
                     HSCTNFGADIPVNSQLVVTTSELRQKLKEKNKFILVDNRTWDEHIGKVSGYTYYDKKG
                     RIPGALYGHSGSDSVSLEEYRNIDNTMRNKYEILEMWDKENIDVNKQLIFMCGSGWRA
                     AEVLTYANVIGVENTSLYSDGWMGWSLDNSNLIEVGEHK"
     gene            15665..16402
                     /locus_tag="KOU88_002120"
     CDS             15665..16402
                     /locus_tag="KOU88_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwmB family TATA-box binding protein"
                     /protein_id="HBK3211998.1"
                     /translation="MKKVKLAISFFILMIIGMTISYADTSINTRYNRLSKALEISEAN
                     FKFYNVKINSVINHNLSNKEFHNIFIEIINNLKLDKKGINWNQKGSGDKIQLCATIKG
                     SDKEISIKGINKNNKESYIVVDILDNKVYKHKEVIYSNVENVLNKYSSQVDVSACIVG
                     EYTKRLQNNKYDDILQKILYNMSAKQIDEVKDVNFLSITAYSKVLNDYELEYLGEKIN
                     LNIGIKYNEDDGKTLIYIATPIIKLDY"
     gene            16423..17676
                     /gene="murA"
                     /locus_tag="KOU88_002121"
     CDS             16423..17676
                     /gene="murA"
                     /locus_tag="KOU88_002121"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBK3211999.1"
                     /translation="MAKIIVKKSNPLKGSVKIDGAKNAVLPIIAATLLANGKSTLNGV
                     PNLRDVHVISDLLRHVGAEVEYKENTLTVDASNIKTCEAPYELVRKMRASFLVMGPLL
                     ARFNSTKISMPGGCAIGTRPIDLHLKGFKALGAKIEMDHGFVEAATEKLVGNKLYLDF
                     PSVGATENIMMAASLAEGTTIIENAAEEPEIVDLANFLNEMGADVKGAGTNTIKIKGV
                     KELKGAEHNVIPDRIEAATYMVAAAMTKGDITVENVLMEHLKPVVAKLREAGCEITEM
                     DNSVRVVGPKVLKPIDIKTLPHPGFPTDVQAQFMAMLTVANGTGVVIETVFENRFMHV
                     AEFNRMGANIKIDGRSAVVNGVDELHGAAVNATDLRAGAALILCGLIAEGETQIGEIY
                     HIQRGYVDIDKKITALGGQIEIVED"
     gene            17763..18827
                     /gene="spoIID"
                     /locus_tag="KOU88_002122"
     CDS             17763..18827
                     /gene="spoIID"
                     /locus_tag="KOU88_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein D"
                     /protein_id="HBK3212000.1"
                     /translation="MKNPLVVLLGFVTCSVLVPSLITLVSYKNVELTEKPESPVSINK
                     TIKKSDIEDKGNKEEKNTVNYETVNKKAPIINVYNHITGKTEKMDMENYLCGVLAGEM
                     SSEFDIEALKAQSVAARTYVVYKQEHGKSSKHKNAVVCTDYKHCQEYKSYDTLKKLNG
                     EEWIKNKYSKIQEAVRGTKGQIITYNDKAILPLYFSTSSGKTENSEEVFSAKYPYLKS
                     VESPYDKYSPKFASTLKISNTDFVKSLRRAYSTIVIDVNNLSKQVSITKRSDAGTVEK
                     IKLGNKELTGKDIRTVFKLNSANFDIKFGEGYIDFVVKGYGHGVGMSQWGAEGMAEEG
                     YKYYDILSHYYTDTKIKDIY"
     gene            18893..19561
                     /locus_tag="KOU88_002123"
     CDS             18893..19561
                     /locus_tag="KOU88_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HBK3212001.1"
                     /translation="MKKKLLEKDGFYLSLFVCVCLLAVGGVWFTNNNVDKLASNKGIM
                     ENANKDSEEEIHLIEKDKKDAIPTATDSKQNLEKAKSKEENKSSTTKLNYIGDKVIRG
                     YSEKEPSYSKTLDVWETHKGVDISCTKGKEVKSLLNGIVVDVFDDEEYGQSVKIKSDN
                     NIVVVYSNLDKNVSVKKEQKVTEGQSLGTVGSTSQIESEEGIHVHLEAYSGEKSIDPM
                     SLIK"
     gene            19659..19919
                     /gene="spoIIID"
                     /locus_tag="KOU88_002124"
     CDS             19659..19919
                     /gene="spoIIID"
                     /locus_tag="KOU88_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation transcriptional regulator SpoIIID"
                     /protein_id="HBK3212002.1"
                     /translation="MRSHIEERAIVVAKYILEKNTTVRQTAKTFGVSKSTIHKDVTER
                     LKEINPSLAKEVKNVLDKNKSERHIRGGLATKLKYEKEHKKM"
     gene            20116..21135
                     /locus_tag="KOU88_002125"
     CDS             20116..21135
                     /locus_tag="KOU88_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein"
                     /protein_id="HBK3212003.1"
                     /translation="MAGADIGIDLGTANVLVYVSGKGIVLEEPSVVAIDKRTDSVLAV
                     GEEAKKMIGRTPGNIVAIRPLRDGVISDYDVTEKMLKSFIDKIVDKKGFGRFFMPRIM
                     VCVPTGVTEVEKRAVEDATRQAGAREVYIIEEPIAAAIGAGVDISQPNGNMIIDIGGG
                     TVDIAVISLGGAVVSESIKVGGDRFDDAIVKYMKKQHNLLIGERTAEKIKFEIGSAFK
                     REEEKYMKITGRNLITGLPSSITINSTEMLEALRECVEQIVVATHAVLEKTPPELAAD
                     IGDVGIIMTGGGSLLYGLDKIIEQRTGITVTIADEPLSCVAKGTGIALGSIDLLETGG
                     SFKRK"
     gene            21151..21579
                     /gene="fabZ"
                     /locus_tag="KOU88_002126"
     CDS             21151..21579
                     /gene="fabZ"
                     /locus_tag="KOU88_002126"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBK3212004.1"
                     /translation="MLNIDEIKKLIPHRYPFLLVDKITELEVGKRAVGIKNVTVNEPF
                     FQGHFPEYPLMPGVLIVEALAQVCGVAMMSVEENKGKLGVFAGIDKVRIKREVRPGDT
                     LTMEVEMTTLRKNIAKADAKAYVGEELVCKGELMFALVEK"
     gene            complement(21690..22199)
                     /gene="yyaC"
                     /locus_tag="KOU88_002127"
     CDS             complement(21690..22199)
                     /gene="yyaC"
                     /locus_tag="KOU88_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protease YyaC"
                     /protein_id="HBK3212005.1"
                     /translation="MYLAKVNYSDDDVIQMLSSVLKTIINENTIVVCIGTDRAIGDTL
                     GPLVGTILKNSNFKYPVYGTLDNPIHALNIYESLDTIKNTHIQGNFLAIDACLGSQSN
                     IGNIQIREGPILPGKGVGKKLPQIGNYSIVGIVDKIDENNKLSFNNIRLSFILDLAET
                     IALALLVST"
     regulatory      22388..22491
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22628..23821
                     /locus_tag="KOU88_002128"
     CDS             22628..23821
                     /locus_tag="KOU88_002128"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBK3212006.1"
                     /translation="MARHLFTSESVTEGHPDKICDQISDSILDALLEKDPQSRVACET
                     TVTTGLVLVAGEISTSAYVDIPKLVRETVREIGYTRAKYGFDCDTCAVITSIDEQSGD
                     IAMGVDEGLESKTGEEIEEEIEKVGAGDQGIMFGFACNETPELMPLPISLAHKLSRRL
                     TEVRKTGLVDYLRPDGKTQVTVEYEGSKAVRVHTVLISAQHCETVSNDKIREDLINHV
                     IKEVIPAELLDEETKIYINPTGRFVIGGPQGDTGLTGRKIIIDTYGGYSRHGGGAFSG
                     KDPTKVDRSAAYAARYVAKNIVAAGLADKCEIELAYAIGIARPLSIFIDTFGTGKVSE
                     EKLVELVNKHFDLRPGAIIRDLDLRKPLYKKVAAYGHFGRTDIDLPWERTDKVEQLRK
                     DALGE"
     gene            24137..25234
                     /locus_tag="KOU88_002129"
     CDS             24137..25234
                     /locus_tag="KOU88_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212007.1"
                     /translation="MSGKVNIKTVISFAGAYVATVIGSGFATGQEILQFFTFYGYAGI
                     IGGIISMVLFSWFGAEVIDKGRELKLKEPIKIYQVYCGKYLGTFFEWFGPLFLFGTLV
                     IMIAGAGATLSEYYGLNPYVGRIGMAIVSLITVSLGLTRLSKILGNIGPIIIIFTLLV
                     GAISLFSNIDALSNAGNMVDSLNIKTATSNGYFSGVLYTCYNVIIVITFLTGMGASAV
                     NKKDAVWGGIVGGVALMAAAIMMNLALLSDIGNIYTKEIPALYLADKISPVIGILFSV
                     VLLLGIYTTAVPLLWSVTNRFVEDDHPKFKIITIVVSILACIGGLLPFDKLVGTLYPY
                     TGYMGILILLCMLYRRITKTEGYKENKSEIS"
     gene            25498..27717
                     /locus_tag="KOU88_002130"
     CDS             25498..27717
                     /locus_tag="KOU88_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBK3212008.1"
                     /translation="MEKLEGMISEIVFKNEDNGYTIAHLVNENDEIVVVGCMPTLAIG
                     ESIEVEGKWVNHKIYGTQFEVNSFMPVTPSSLEGIYVYLSSGMIHGIGEKMAKRIIDK
                     FGVDTLEVIQNSPEKLQEVEGIGSKKVKQIVKSYEEDRELRNIIIQLSPFGITPNYCL
                     KIYKKYKSSAIEVINKNPYQLAEDIRGIGFKVADSIASKIGIDKNSKDRICQGILYTL
                     NKSLSNGHTYLPEHVLIQDSEKLLELNGEILKECVMMLVYNQKIHIEKVNNENLIYLM
                     PYYLAENGVCSQIVKLSQYEFEDLKIDIDNEINVLEEDKKIKLAEKQILAVKESVNSG
                     VLIITGGPGTGKTTTINAIIDIFENNGKSVTLAAPTGRAAKRMSETSNKEAKTIHRLL
                     EMGFSTDDDLTFFKDEEDPINSDVIIVDEVSMVDIILMYNLLRAIKLGTRVILVGDSD
                     QLPSVGAGNVLKDMINSNIINVVKLNEIFRQAQESMIIVNAHKINNGEPLYLNTKGKD
                     FFFIRKSTNEEILNEIIGLVNERLPKFYKVDKLKDIQVLSSMRKGELGVTNLNIELQK
                     YLNKKEKFKVEESFSKRLFRVGDKVMQVKNNYTKKWETEDQKESGEGIYNGDIGYVYH
                     IDKDKKTIYILFDQTKIVSYLYDELDEIDHSFCTTIHKSQGSEFPVVVLPIAWAPPML
                     LSRNLLYTAVTRAKKLVVLVGDVKYLEYMIKNNRVNQRYSNLGYKLNKFKQEGLLIE"
     gene            27720..28502
                     /locus_tag="KOU88_002131"
     CDS             27720..28502
                     /locus_tag="KOU88_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBK3212009.1"
                     /translation="MKICNDNFIKNFKNMINKCLDFIYPENISCIICDKSIKKTNTYS
                     ICKSCFKEMNFIQDGCMKCGKPIIRHSIEKEFIEECSYCFNKDFYFDKSISCIEYNDV
                     TKKMVLGLKYNQKTFMAKYIAQIMKEKLYLENIKFDYILFVPLHKKRLNKRGFNQAQK
                     IAFNLSKIVNIPLLDCISRKKYTRMLYKLNKKERKEELKNVFVVKENVKLINNKNILL
                     IDDIFTTGLTTNEISKLLKLSGANKVFILTLLTKANDNYIME"
     gene            28834..30747
                     /locus_tag="KOU88_002132"
     CDS             28834..30747
                     /locus_tag="KOU88_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3212010.1"
                     /translation="MICLNKRQENLLTTLLLKEEFINVNKIANDFECSERTIRNDCKY
                     IDEWLSTFCNAYIKRKPNIGIKFSGDGTDKILVNQKLRGEVKRVNSELHKQVEILNLL
                     LCNNKKVTLNDLSNKLYINKNIVREEISKLSVALNNYNLNISTKKGSGIYIQGDEKDI
                     RIMLVSFLFKYIDKYRLNIDEIEYFHIVDIIIVKNIMLTIEEDMDIRLTDISFKQLML
                     FLLINIIRIRLGNSLKVSNTKKELKLKMLILDIEDELKSNLSIVLNYEEKLFIESLIL
                     GMNKQINSNNIKKSLYLNEELASYTKKIINLVSEESGINFNNDILLYEQLICHLNVTM
                     HQMKSNVYLENPLLDNIKTKFCFLFTVISSSIEIELKGKQITEDEIGYLTLHFQTSLE
                     RKYSKRESNKKASIVCPFSFGVSMLLKVKIEKRFDNIKIIETLREEDLKRDNFNKTID
                     FIIAFQEYENIQKPIFITTPLFTDEDENKLKEFTNKIKEKDTSYKLMNRLMMSDYLIR
                     ELEHDDIYEAITYLTNLLIEKHYAEKEYLQSIITREKSYPTNVGKGILFPHGDMKYIK
                     QSVLCFARLKTPIKIRNGKDIKIILLLAYKKDDDRKVFRELFKEISNLTEDENMLDIL
                     SKCDIEKVKDILI"
     gene            30888..31196
                     /locus_tag="KOU88_002133"
     CDS             30888..31196
                     /locus_tag="KOU88_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK3212011.1"
                     /translation="MEEIVLKIIIHAGNAKSMLYEALDYAKENDFKKADELIENANEE
                     ILKAHKVQTELIQKEAGGDKSDISILLIHSQDHLMTCMSERNLIKEMIMLRKEIQKLK
                     "
     gene            31220..31546
                     /locus_tag="KOU88_002134"
     CDS             31220..31546
                     /locus_tag="KOU88_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3212012.1"
                     /translation="MKRKVYLFCSFGMSTSLLADKMQKVADEHNLPIEVEAFPIAEID
                     KIVEEKNPDCILLGPQVKYMLKELKPKFEAQGKLIDIINEVDYGTMNGEKVLKLAIKL
                     IKSKQA"
     gene            31585..32919
                     /gene="celB"
                     /locus_tag="KOU88_002135"
     CDS             31585..32919
                     /gene="celB"
                     /locus_tag="KOU88_002135"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBK3212013.1"
                     /translation="MNRLERILMPLAEKIGKNKLLIAIRDGFLVSSPLLIIGSLFLLV
                     ANFPIKGWNEFVGQIFGPDWAVKLQQPTVATFEVMTLLAVLGIGYSYAKQIDVDPIAS
                     AAVAIVAFFIITPFVIPYTPEGTESVYMVTGIPLGWMGSKGMFVGMITAITSVKLFAA
                     VVKKGWTLKMPDGVPPTVSKSFAALIPSAIVMVVFFLVKIAFEATPYGSIHEFIFKFL
                     QMPLLKLGNSLGAMAIAYIFLHLFWFFGINGSSVVGAVYNPILKILSAENLAAFQAGS
                     KIPNIITGQFQDMFATFGGAGSTLSLVIAMLLICKSKRIKSMGKLSILPGIFGINEPL
                     IFGLPIMLNPILLIPFAIVPTINIIIAYFCMSAGLVPLTNGVQLPWTTPIIFSGFLTT
                     GWQGAVLQLVLLILGIFMYIPFIKMLDKQYLREENETVEEEDDDISFDDLVL"
     gene            32930..33448
                     /locus_tag="KOU88_002136"
     CDS             32930..33448
                     /locus_tag="KOU88_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/betaine/sarcosine/D-proline family
                     reductase selenoprotein B"
                     /protein_id="HBK3212014.1"
                     /translation="MKKIVMILDQIQAGAGGKEKSNIPPAGKSSPLGPGVMMEQFLNE
                     SKVIATLFCGDEFFVNNQEEVTSKMIAMVKKLNPDVVICGPSFNYENFSKMSAILSKN
                     INDKTDIPAFAAMSEENIDVINEYKNDICIVKTPKKGGIGLTDSLNNICKLAKAIANK
                     EDITLMKEEFCY"
     gene            33544..34503
                     /locus_tag="KOU88_002137"
     CDS             33544..34503
                     /locus_tag="KOU88_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase"
                     /protein_id="HBK3212015.1"
                     /translation="MWGMIATWRMALEGITEASEHLEKGMEAGDAVELAVRRVEDYPF
                     YKSVGYGGLPNENCEVELDAAFMDGNTLDIGAVAGIRDYSNPVSIARKLSYEKVNNFL
                     VGIGAEDYAHKNGFERKNMLTDRAKLHYKKRKKETLDKGLSPYAGHDTVGMISLDKTG
                     KMCVATSTSGLFMKKRGRIGDSALSGSGFYVDSSIGGATATGLGEDLMKGCISYEIVR
                     LMKEGKHPQEACDIAVNELDKQLIKRRGKAGDLSLVAMNNKGEWGVATNIADFTFSVV
                     TKEESPTVYISNRVDGKTIHKVISNEWMEAYEARIKAPIEVSE"
     gene            34552..35604
                     /locus_tag="KOU88_002138"
     CDS             34552..35604
                     /locus_tag="KOU88_002138"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBK3212016.1"
                     /translation="MNIISNKIDELKEDLLSDIIDIVKIPSVKGESENGFPFGEKVGE
                     ALNKALEISEKLGFKVRNLDNYIGYAEHGDSDDYVCVIGHVDVVHEGDGWKHQPYKGE
                     ETNGRIYGRGVLDNKGPIMSALYGLYAIKELNLKLDKRVRIIFGTNEESGFEDIPYYL
                     EKEKAPIMGFTPDCKYPVVYGEKGMAKIRIKSKINYEEDVYLGFIENMSENVLVTYKE
                     LNIENSDTILDIKVKYDFSYKLKDVLDEIKASFPNSIDIEVISNFNPVYFDKESNLVK
                     KLQLAYERVTSLDGTPVTTNGGTYAKVMPNIVPFGPSFPGQKGIAHNPDEYMDIEDII
                     LNAKIFANAIYELAKE"
     gene            35607..36281
                     /locus_tag="KOU88_002139"
     CDS             35607..36281
                     /locus_tag="KOU88_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBK3212017.1"
                     /translation="MLEIIGMSVEDAKIIEDCGADRIELVSALTEGGLTPSFGLIESV
                     VNSVKIPVNVMIRHHAKSFVYSKEDISIMQKDISVVKEIGANGVVFGVLDKNNNIDEK
                     NLNVLLKCCDNLDVTFHRAIDESNTIDSVKILKDYDKITNILTSGGKGSIVHNIQMIK
                     NMMLSSNHIKILLGGGLNFNNIEKIKELTKASNFHFGTAIRINNSPFEDIDRQKLKQL
                     VNIISR"
     gene            36834..37385
                     /gene="raiA"
                     /locus_tag="KOU88_002140"
     CDS             36834..37385
                     /gene="raiA"
                     /locus_tag="KOU88_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBK3212018.1"
                     /translation="MNIIISGKQIELTDAIKNKIETKLSKLDNYIHPDTDVKVTVSAR
                     KARQKIEVTIATVNGPIIRAEDMQENLYTAIDVVYDKLSKQLKKYKKRLQDKHKDNKS
                     IRFQDAEINLADEQEDYGDENQELVIQRRKKFSVKPMSEEEAVLQMELIGHDFYMFKN
                     IDSDEIAVVYKRNNGGYGIIEHE"
     gene            37517..40192
                     /gene="secA"
                     /locus_tag="KOU88_002141"
     CDS             37517..40192
                     /gene="secA"
                     /locus_tag="KOU88_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBK3212019.1"
                     /translation="MSFMDNLFNMADKKELKKFNKTVDIIDSLEPKFESMADSELKNM
                     TNIFKERLANGESIDDILPEAFAVVREVSKRVLGLRHYRVQMIGGIVLHQGRIAEMKT
                     GEGKTLVATAPVYLNALTGKGVHVVTVNDYLAKRDRDQMAKIYEFLGMSVGVIIHGQN
                     PKVRKEQYDCDITYGTNNEYGFDYLKDNMVIHKEQRVQRGLNYAIVDEVDSILIDEAR
                     TPLIISGPGDKSTHLYSDANTFVLTLKPDDYELEEKDKAVSLTASGIQKAEVYFNVDN
                     ITDISHTELYHHINQALRAHVIMKKDVDYVAKDGEIVIVDEFTGRLMFGRRYSEGLHQ
                     AIEAKEGLKIQRESKTLATVTFQNYFRMYKKLSGMTGTAKTEEEEFKAIYKMDVFQVP
                     TNKLMIREDLPDCVYKSEIGKFNAVAQEIIERHKVNQPILVGTVSIEKSELLSQILKK
                     KGIKHEVLNAKHHDKEAEIIAQAGRLGAVTIATNMAGRGTDIVLGGNPDFLTKREMRR
                     NGFKEEIVNRVDTPIEGIPVKGNEILFEAREEYEKLFEKFKQQTQEEQKQVVEAGGLA
                     IIGTERHESRRIDNQLRGRAGRQGDPGSSRFYIGLDDDLMRLFGSDRISGIVDKIGLE
                     EDMPIEHRILSKSIEGAQKKVEGKNFGIRKHVLQYDDVMNKQREIIYAERKRVLEGED
                     LQEQIQSMTHSIIEEAVTLYTQDKGFDEEGFKEHMYNLFLPKGSIEIPEIEKLNPVEI
                     TEKVYEIAMKIYTSKEEQVGYERMREVERVILLQAVDNHWIDHIDAMDQLRQGIGLRA
                     VGQQDPVIAYKMEGFDMFDEMNKHIKEDTVRYLFNITIETPVERKAVVDVENLSSPSD
                     GTLPTSKTVKKDEKVGRNDLCPCGSGKKYKNCCGR"
     gene            40207..41314
                     /gene="prfB"
                     /locus_tag="KOU88_002142"
     CDS             join(40207..40281,40283..41314)
                     /gene="prfB"
                     /locus_tag="KOU88_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_153309863.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBK3212020.1"
                     /translation="MLKLQEYRHSMEQMASNLEELRVSLDIASLMKNIQINEEKMNQQ
                     DFWNDNEVAQRVLQENKSLKETLEEYESLKSLLEDIEVLIEIGLEEDDDSVERDIEKS
                     IESMEEKLSEMKIKTLLNGEYDKNNAILSINAGTGGLDAQDWAQMLLRMYIRWSESKG
                     YKVKLLDIISDPEAGIKTATILVEGTNAYGYLKSEKGVHRLVRISPFDPSGKRHTSFA
                     SIDVTPELDENIEVEINPSDLKIDTYRASGAGGQHVNTTDSAVRITHIPTGVVVQCQN
                     ERSQHLNKDRAMRLLMAKLIELKELEQKEKIEDIQGKYSQITWGSQIRSYVFQPYKLV
                     KDHRTNAEFGNVDSVMNGNIDLFINEYLKMNKIV"
     gene            41458..43599
                     /locus_tag="KOU88_002143"
     CDS             41458..43599
                     /locus_tag="KOU88_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBK3212021.1"
                     /translation="MDINQILKKEFNLRDEQINNTLKLIDEGNTIPFIARYRKEMTGE
                     MSDVTLREFYEKLMYLRNLQSRKDDVVRLIDEQGKLTDEITQNIEKAKTLQEVEDIYA
                     PYKQKKRTRATIAKEKGLENLALSILENNLDNIEIEAKNYLDEEKEVLSIEDALKGAR
                     DIIAELVSDDAKIRKYIRELALREGMIVSKSATDEKSVYDMYYDYSEAVKSMAPHRVL
                     AINRGEKESFLKVKLEINNDKVLNYIINEYVNDKNFKNKEEIVSSIEDSYKRLIFPSI
                     EREIRNHLTEIAQERAISVFGKNVKSLLLQPPVKDKVVMGFDPAFRTGCKIAVVDKNG
                     KLLDYTTVYPTDPQNDVEGAKKVLKGLIEKYDIDIISIGNGTASRESETFVSEMIKEI
                     DSEVQYVIVSEAGASVYSASELANEEHPDINVSIRGAISIARRLQDPLAELVKIDPKS
                     IGVGQYQHDLNKKRLEEVLDGVVEDSVNSVGVDLNTASYSLLEHVAGISKAIAKNIIA
                     YREENGDFTSRAQLKKVKRLGPQAFTQCAGFMRILEGKNPLDNTGVHPESYDICKKMI
                     EIIGYSLDDVKNKNIGEIDEKIKEIGLRELSEKLEVGQVTLKDIIAEIKKPGRDPREE
                     GIKPILRTDVLKIEDIQEGMTLKGTIRNVVDFGAFVDIGIKNDGLVHKSEMSNSFVKD
                     PMSIVTVGDIVDVKVIGIDLNKKRVALSMKK"
     gene            43747..44913
                     /locus_tag="KOU88_002144"
     CDS             43747..44913
                     /locus_tag="KOU88_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3212022.1"
                     /translation="MIFIKNGKINTITNGIIHGDILIDEGKIIEIGEDLIAPLDVEVI
                     DASNKLVFPGFIDAHTHLGLWEDGIGFEGADGNEETDPITPQLNPIDGINPMDRTFKE
                     AFEGGITSVCTTPGSANVMGGQCIAIKTCGKRIDKMVIKNPVASKIAFGENPKSCYGQ
                     DDKSPQTRMAIAALLRENLKKAEEYLEDIDMYESHDDEDCEKPEYDIKMESLIPVLRR
                     EIPFKAHAHRADDMFTAIRIAKEFNLKLTLDHCTEGHLIVDELVEEEFPVIVGPSLSE
                     RSKFELRNLTFNTAGILSNAGLDVCIMTDHPVIPVQYLPICAGIAVKHGMKEEKAIES
                     ITINPAKALGIEDRVGSIEVGKDADLVIWDNSPLEIQSNVLYTIINGKVVYEKK"
     regulatory      44973..45090
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            45215..45820
                     /locus_tag="KOU88_002145"
     CDS             45215..45820
                     /locus_tag="KOU88_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK3212023.1"
                     /translation="MQNTAKRGNMISTRTLVVMSILSAISYLLMFIQAPIPGIFPDFL
                     KIDLSDIPAIFGGMSLGPLVGFGIVVVKNVLQAITATTTGGIGEFANILIGGSYVMIL
                     CYSYKRSGDLKGVLIGFVLGTISMTIIGSLVNYFVMLPLYGQLMGLDAIIGLGSAINP
                     QVHDLFTFVIWMIAPFNVLKAVIISLVTLPLYKKMGNIIKK"
     gene            46149..47189
                     /locus_tag="KOU88_002146"
     CDS             46149..47189
                     /locus_tag="KOU88_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBK3212024.1"
                     /translation="MHLSKKIKKLFLDDKGYYFNSNWKDIHIGIYDTKLGDSLKYITN
                     EYIENMERVKYDYRELKNIENQTDGMCILAIRQNYKALEYVKNQTEELCLEAIKYNYK
                     ALEYVKEQTEYLCLEAIKKDCNALKYVRNKTEGLIIKAISHSSNIDVVSILKALETQT
                     RRICLEAIKKDGRCLAYVREQSEELCIEAIKQNYKALKYVKNQTEKMCIESVRQNGMA
                     LQYVNKQTDKICIEAVKQDGRSIQFVNNKTEEICINAIRYLNKKYNIKDVLSYIDKYT
                     EDICIEIVRQNGKMLMYIKNQTEKMCIEAVKENYKSLKYVKEQSERICKEALKQNHKA
                     KEYVKIAIDDCI"
     gene            47328..47780
                     /gene="tsaE"
                     /locus_tag="KOU88_002147"
     CDS             47328..47780
                     /gene="tsaE"
                     /locus_tag="KOU88_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBK3212025.1"
                     /translation="MAKIYLENENKTREIGYKLGKLLKEGSVICLVGDLGAGKTTMTQ
                     SLADSLGIEDYITSPTFTIINEYEGKIPLYHFDVYRIGSSDEMYDIGYDEYVNSNGIC
                     IIEWANLIEDILPKEYLNIELRYKDEGREMILTPKGEFYKEIVEELIK"
     gene            47780..48496
                     /gene="tsaB"
                     /locus_tag="KOU88_002148"
     CDS             47780..48496
                     /gene="tsaB"
                     /locus_tag="KOU88_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBK3212026.1"
                     /translation="MKILGMDTSSMAASVAVVEDDNLICEFTVNNKKTHSQKLMPMIE
                     NMLSMSDLSIKDMDLLAVCIGPGSFTGLRIGMATVKAMAHVNNIPIIAVNSLESLANN
                     INFCDRKICCILDAQKNQVYSAKYKFENGEMIELDGVDVVEFDALVDEIVSTNEEFII
                     VGEAVYKYKDKLENIKNIKIPSPANNVSNAGSLCSLALNKYNKNIDVHTCYTINPMYI
                     RKSQAEVQYDEKMKRLNNGR"
     gene            48486..48962
                     /gene="rimI"
                     /locus_tag="KOU88_002149"
     CDS             48486..48962
                     /gene="rimI"
                     /locus_tag="KOU88_002149"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBK3212027.1"
                     /translation="MEDNTKLIVDDIKIEEMTTEDIDEVFEVEKNCFEDYWSKESFRK
                     ELSNEVARYIVAKLNGKIVGYVGIWLILDEGHINNVAVHSDYRGKKIGDKLIKGIVDL
                     CKDNNIASMTLEVRASNKIAQNLYRKYGFKMGGIRKEYYSDNKEDAIIMWNQLKEV"
     gene            48968..49984
                     /gene="tsaD"
                     /locus_tag="KOU88_002150"
     CDS             48968..49984
                     /gene="tsaD"
                     /locus_tag="KOU88_002150"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBK3212028.1"
                     /translation="MSDIITLAIESSCDETAASVLKNGREILSNIISTQIETHKKFGG
                     VVPEVASRKHVENIDIVVQEALDKANIGFNDIDHIAVTYGPGLVGALLVGLSYAKALA
                     YTLNIPLVGVNHIEGHLSANYIEHKDLKPPFITLIVSGGHTHLVEVKDYGKYEILGKT
                     RDDASGEAFDKISRAMNLGYPGGPIIDNLAKNGNKHAIEFPRAYLEEDSYDFSFSGLK
                     SSVLNYLNGKRMKNEEIVVEDVAASFQEAVVEVLSTKALKAVKDKGYNIITLSGGVAS
                     NSGLRAKITELAKDNGITVKYPPLILCTDNAAMIGCAGYYNFINGKTHDMSLNAVPNL
                     KINQ"
     gene            50281..52989
                     /gene="hpdB"
                     /locus_tag="KOU88_002151"
     CDS             50281..52989
                     /gene="hpdB"
                     /locus_tag="KOU88_002151"
                     /EC_number="4.1.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase large
                     subunit"
                     /protein_id="HBK3212029.1"
                     /translation="MSQSKEDKIRSILEAKNIKSNFQNKENLSEFNEKKASKRAEDLL
                     DVYYNTLSTADMEFPYWYNREYRKSDGDIPVVRRAKALKAAFSHMTPNIIPGEKIVMQ
                     KTRHYRGSFPMPWVSESFFVAQGEQMREEAKKLASNTADELTKFGSGGGNVTESFGNV
                     VSIAGKFGMRKEEVPVLVKMAKEWVGKSVEDLGFHYEKMMPDYDLKENLMSTLICMFD
                     SGYTLPQGREVINYFYPLNYGLDGIIEMAKECKKAVAGNASGDGLIGMDRLYFYEAVI
                     QVIEGLQTWILNYAKHAKYLESIETDLEAKKEYSDLVEILEHIAHKQPRTFREALQLT
                     YTIHIASVNEDAISGMSIGRFGQILYPWYEQDIEKGLITKEEVIELLELYRIKITCID
                     CFASAGVNGGVLSGNTFNTLSIGGLKEDGSTGANELEELLLEASMRCRTPQPSLTMLY
                     DEKLPEDFLMKAAECTKLGSGYPAWVNNSNGTTFMMKQFADEGMTVEEARAFALGGCL
                     ETSPGCWKQLTLNGKTYSIAGGAGQSAGSGVHFIANPKILELVLMNGKDYRMNIQVFE
                     PHNKPLDTYEEVIEVFKDYYKQAINVLERANNIELDIWRKFDTSIINSLLKPDCLDKG
                     QHIGNMGYRYNATLNVETCGTVTMVNSFAALKKLVYDDKAFTIEEMKDAILNNFGFKD
                     ALEVGNYSMADQVKVDKTGKYDAIYKACLDAPKYGNNDLYADNILKNYEVWLSKVCEE
                     AQSLYAKKMYPCQISVSTHGPQGAATLATPDGRLSGTTYSDGSVSAYAGTDKNGVYAL
                     FESATIWDQAVVQNSQMNLKLHPTTIKGQQGTKKLLDLTRSYLRKGGFHIQYNVVDSE
                     TLKDAQKNPDNYRQLMVRVAGFTQYWCELGKPIQDEVIARTEYEGV"
     gene            52993..53250
                     /gene="hpdC"
                     /locus_tag="KOU88_002152"
     CDS             52993..53250
                     /gene="hpdC"
                     /locus_tag="KOU88_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase small
                     subunit"
                     /protein_id="HBK3212030.1"
                     /translation="MRKHSDCMNFCAVDATKGICRLSKQMINLDDAACPEIKVMPKCK
                     NCKNFVEANDEGIGKCVGLEKEDWVYSTLNAITCEGHVFNE"
     gene            53243..54193
                     /gene="hpdA"
                     /locus_tag="KOU88_002153"
     CDS             53243..54193
                     /gene="hpdA"
                     /locus_tag="KOU88_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate decarboxylase activase"
                     /protein_id="HBK3212031.1"
                     /translation="MSSQKQLEGMIFDVQSFSVHDGPGCRTTVFLNGCPLSCKWCANP
                     ESWTVRPHMMFSELSCQYENGCTVCHGKCKNGALSFNLDNKPVIDWNICKDCESFECV
                     NSCYYNAFKLCAKPYTVDELVQVIKRDSNNWRSNGGVTFSGGEPLLQHEFLHEVLLKC
                     HEVNIHTAIETSACVSNEVFNKIFNDIDFAFIDIKHMDREKHKEQTGVYNDLILENIS
                     NLANSDWNGRLVLRVPVISGFNDSVENISDIISFMHKNNLVEINLLPFHRLGESKWIQ
                     LGKEYEYSDKGDVDEGHLEELQDIFLDNGIACYVGHETAF"
     gene            54509..55447
                     /locus_tag="KOU88_002154"
     CDS             54509..55447
                     /locus_tag="KOU88_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK3212032.1"
                     /translation="MNKSWSNLIIKNKDKKVRSGWIIIAVMATFYILQYYLSMILVEI
                     IRKILVATGDINLKTNYFSEYANWLNDVGLQIVFQILTDSLMIIIPIIVWRFIMKNPI
                     SEMGLHSYRIKKKEGYVGMLLGIFNCTVIFIITITIGGGHVTSWVPKISPLTVSWILV
                     FILVAFAEEILNRGFFMAVLRRCKNIYFIMIVPSVIFGLIHIWNPDVTFLSVINIIII
                     GILFSYMFIKSSNIWMCIGYHFTWNVFQGIIYGMPVSGLQVPGIITTQITHGNLLNGG
                     MFGIEGGILTTFVNLLSFIFVWYYYRDSKYDFVSNK"
     gene            complement(55569..56370)
                     /locus_tag="KOU88_002155"
                     /pseudo
     CDS             complement(55569..56370)
                     /locus_tag="KOU88_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901671.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
BASE COUNT        22634 a         6120 c        10720 g        17052 t
ORIGIN      
        1 cggaatggat aagcgctgaa agcatctaag cgcgaagcca acttcaagat aagatttccc
       61 accgcaaggg taagacccca gaaagactat ctggttgata ggtcgaaggt gtaagtgcag
      121 caatgtattt agcttatcga tactaatagg tcgaggactt gaccaatatt tatttgatgt
      181 tcattcatta agatatatgt gtagttttta gagtgctaac tctaaagaaa ctagtattgc
      241 taggttctat aaacttatta aaaacttaat agaaatatta agcataaaga ttatgtggtt
      301 acaatagcag agaggataca cctgttccca ttccgaacac agaagttaag ctctctagcg
      361 ctgatggtac ttggtgggaa actgcctggg agagtaggac gtagccacgt taaatgttcc
      421 aaggtagctc aacggtggag caaccggctg ttaaccggta ggctgtgggt tcgagcccca
      481 cccttggagc caaaaaagcc gaagtggcgg aactggcaga cgcacaggac ttaaaatcct
      541 gcgggactta cctctcgtac cggttcgatt ccggtcttcg gcacttataa aacaatatcg
      601 cggggtggag cagttggcag ctcgtcgggc tcataacccg aaggtcgtag gttcaagtcc
      661 tgcctccgca accattaaaa cggctcgttg gtcaagaggt taagacaccg ccctttcacg
      721 gcggtaacag gggttcaatt cccctacgag tcaccaattc aattaaatat gcgggtgtag
      781 ctcaatggta gagttctggc cttccaagcc agctgtgagg gttcgatccc cttcacccgc
      841 tccaaaaatg ggaccatagc tcagctggga gagcacctgc cttacaagca gggggtcaca
      901 ggttcgagcc ctgttggtcc caccattcgc ggcctggtag ttcagttggt tagaatgcca
      961 gcctgtcacg ctggaggtcg agggttcgag ccccttccag gtcgccaaat taaataagcg
     1021 ggaatagttc agtggtagag cgcaaccttg ccaaggttga agtcgcgagt tcgaatctcg
     1081 tttcccgctc cataataact tgggtgcata gctcagctgg atagagcaac gcccttctaa
     1141 ggcgtgtgtc cggggttcga atccctgtgc gctcattaag aaaagtttac tataaattat
     1201 agtaaacttt tatattgttt aaaaagacac aggaaacatg tatattacct gtgtcttttt
     1261 atttataaac tttaaactat gtaaaaatta cagtatattc taatagagtt acagtatatt
     1321 cattaatatt gtaaacatac ggagggtaat gtataatagt ctacaagatg tttatgaagg
     1381 catcagttaa atataataaa tataactaat tagtaagagt tatatacatt atattgtata
     1441 ctttatggta tttatatatt gaaataactt atgaagttat ttataaagag attcatgagc
     1501 atatttttgt ctaaacaata agtataagaa attataaaaa attagagact atagtgaatt
     1561 tacaatttaa tgtaatattt ataagttata ctaaataaat tattatactg tgaaatggat
     1621 atataacttt aggtattgtg tattattttc actgtaggag attatatcta gttatacata
     1681 ataagtttta atgatagttt atagtaagat attaaaataa atttatctaa tctagatatg
     1741 aaataagtta ttactttaat ataaaaatga atctaatgga ataatattga tgataagtaa
     1801 tatttagatt ttgtatttgt ttatagttaa taagtggatt atagaattta taataattaa
     1861 tatatattaa acaaagatat attaagatat tttagaacac aaaactgcat taaggcgcga
     1921 gtactatttt gtattcgcgc cttgatggtt tgagttattt gagtaaaaac taactttaat
     1981 aagaaatctg tatttattaa gttgatattt ttaatgtgtt tagagattat ttaacaatct
     2041 ccaaatataa aactagaatt atttacataa aagttaaata gtttgtatag agttagattt
     2101 atatagtata atacttagtg taaataatta agaagttatc aaacaggagg ataaaactgt
     2161 gttagatata aattcttttt taaatggatt ttttaatata atattaagaa tgagtatata
     2221 tgatttaatt gacatatcta tagtagcgta tattttttac aaaatattta tgtttataaa
     2281 agatacaaga gcagaacaag tgtttaaagg tataatattt cttttattag caactcaact
     2341 tagtaacacc tttaaattgc ataccgttta ttggatatct cttaaagctt tagattatgg
     2401 agttatagct gctcttataa tttttcaacc agaatttaga gcaggacttg aacatatagg
     2461 aagagcaaag tttaatttat ttggaaagaa tgtaaatact tctgaagaaa ctctcaatag
     2521 aaatatagaa gaaattgtag aagctttata ttcactttct agacaaaaaa taggagctct
     2581 tatcataatg gagagagaaa ctagaataag tgatataata aatacaggaa ctattattga
     2641 tgctgaaatt tctaggcaac tattaataaa tatatttata ccaaatacac cattacacga
     2701 tggagctgtt gtaattagag attctaaggt aaaagcagct gcatgttttt tgccattgac
     2761 agaaagtaag gatttaagta aagatttggg tactagacat agagcaggaa taggggtaag
     2821 tgaggtgtct gactgtataa ctttgattgt atcagaggaa acaggtggcg tatcaattgc
     2881 taaagcaggt aagttatata gagatatttc tagagaaaga atgatgaata tattacgtag
     2941 taatttaaaa acaaatacag aaacaagaag ttttttcaaa ggtggtatat ttaaatgata
     3001 aatagactaa aaaataatac caaaataaaa ataatatcat ttttaagtgc aattgcatta
     3061 tggatgtatg ttatggctgt agttgaccct gaagaaacta aagggtttga agatatacct
     3121 gtatctataa gtaatatgag tgatttaaag gataaaaatc ttgttatata tccagacgaa
     3181 aaattaacag cagatgtata tataaaaggt agtttatcaa aggtacaaag tgttaaaaaa
     3241 gaagatatac atgtatatgg aaccattgaa gacccaatac aaggacagaa ggaagtatat
     3301 ttaaaagcaa atattcctca aggtgttact ctagaattta agcatgatgt tttagtagta
     3361 aatcttgaaa aaaacataaa agaaaaaaga gatataaagg tagaagtaag tggaaattca
     3421 aaaagaaata taaataaaat tgaacttagt aaggaatttg tcgatgtatc aggtccaaga
     3481 actctagtta aagaagtcaa aagtgtaaga gctaatctag atgttggtaa tgagacagat
     3541 gatttttcta aaaaattgca attaatacca ttaaatagtg atggaactaa ggttgaagga
     3601 gtaacattaa gttcatcctt tgtgactgca aagatagaac tattgaagga aaaaattgtc
     3661 ccaataagag taagtctaaa tgataataaa gataatgatg tactgaaaaa ctataaatta
     3721 agtaaggaac aagttacaat aaaaggaaag aaagaagata tagacaaaat aagttatatt
     3781 aagacaaaac ctattgactt agctgatttg gctaatggtg aagaaaaaga agttagctta
     3841 gaaattccag agggtataac tcttgaggat agctctataa caattaaatt aaatgataca
     3901 aaacaattga gtgcagaatt tttatataat gcgggagata ttgaattaag aaatatccca
     3961 acaaatatgg ataatccaaa tgtaatttct gatgtagata taaaagttgt tgtagagtca
     4021 acggaggatt tgagtaagtt aaataaaaaa gatatttcat tatatattga tttatcacaa
     4081 ggccctgagg aagatagtaa atataaaata aaatatgaaa caacatatca atttaaaaaa
     4141 ataaatatag aacctaatat tgttgaagtg gaatgaacaa atatttcgaa tatttagttg
     4201 ttacaagatg cgacaaaaaa acctataaaa ttaagtttgt taattttatg tttttgttgc
     4261 atcttgttta ttttagttat attataaaat aaggacaatg agatatttgt taaatctaaa
     4321 aagcgctaga tatatgaaaa aagactgata aatagattta aataaatatt ttgaattaaa
     4381 tatttcaatt atctctagga aaacgttgct gaacgagtta taatttaatt gagatataaa
     4441 aagttctatt tcaaaaaatt caagatgagg tggaaatgca tgagaagttt tgaagaagta
     4501 attaagtttg caaaagaaag aggacctaaa actatatcag tagcatgttg ccaagataaa
     4561 gaagttttaa tggcagttga aatggctaga aaagaaaaaa tagcaaatgc cattttagta
     4621 ggagatatag aaaagactaa agaaattgca aaaagcatag acatggatat cgaaaattat
     4681 gaactgatag atataaaaga tttagcagaa gcatctctaa aatctgttga attagtttca
     4741 caaggaaaag ccgacatggt aatgaaaggc ttagtagaca catcaataat actaaaagca
     4801 gttttaaata aagaagtagg tcttagaact ggaaatgtat taagtcacgt agcagtattt
     4861 gatgtagagg gatatgatag attatttttc gtaactgacg cagctatgaa cttagctcct
     4921 gatacaaata ctaaaaagca aatcatagaa aatgcttgca cagtagcaca ttcattagat
     4981 ataagtgaac caaaagttgc tgcaatatgc gcaaaagaaa aagtaaatcc aaaaatgaaa
     5041 gatacagttg aagctaaaga actagaagaa atgtatgaaa gaggagaaat caaaggttgt
     5101 atggttggtg gaccttttgc aattgataat gcagtatctt tagaagcagc taaacataaa
     5161 ggtataaatc atcctgtagc aggaagagct gatatattat tagccccaga tattgaaggt
     5221 ggtaacatat tatataaagc tttggtattc ttctcaaaat caaaaaatgc aggagttata
     5281 gttggggcta aagcaccaat aatattaact tctagagcag acagtgaaga aactaaacta
     5341 aactcaatag ctttaggtgt tttaatggca gcaaaggcat aattttaagg gggaaatagg
     5401 caaatgagca aaatatttaa aatcttaaca ataaatcctg gttcgacatc aactaaaata
     5461 gctgtatttg ataatgagga tttagtattt gaaaaaactt taagacattc ttcagaagaa
     5521 ataggaaaat atgagaaggt gtctgaccaa tttgaatttc gtaaacaagt aatagaagaa
     5581 gctctaaaag aaggtggagt aaaaacatct gaattagatg ctgtagtagg tagaggagga
     5641 cttcttaaac ctataaaagg tggtacttat tcagtaagtg ctgctatgat tgaagattta
     5701 aaagtgggag ttttaggaga acacgcttca aacctaggtg gaataatagc aaaacaaata
     5761 ggtgaagaag taaatgttcc ttcatacata gtagaccctg ttgttgtaga tgaattagaa
     5821 gatgttgcta gaatttctgg tatgcctgaa ataagtagag caagtgtagt acatgcttta
     5881 aatcaaaagg caatagcaag aagatatgct agagaaataa acaagaaata tgaagatata
     5941 aatcttatag ttgcacacat gggtggagga gtttctgttg gagctcataa aaatggtaaa
     6001 atagtagatg ttgcaaacgc attagatgga gaaggacctt tctctccaga aagaagtggt
     6061 ggactaccag taggtgcatt agtaaaaatg tgctttagtg gaaaatatac tcaagatgaa
     6121 attaaaaaga aaataaaagg taatggcgga ttagttgcat acttaaacac taatgatgct
     6181 agagaagttg aagaaagaat tgaagctggt gatgaaaaag ctaaattagt atatgaagct
     6241 atggcatatc aaatctctaa agaaatagga gctagtgctg cagttcttaa gggagatgta
     6301 aaagcaatat tattaactgg tggaatcgca tattcaaaaa tgtttacaga aatgattgca
     6361 gatagagtta aatttatagc agatgtaaaa gtttatccag gtgaagatga aatgattgca
     6421 ttagctcaag gtggacttag agttttaact ggtgaagaag aggctcaagt ttatgataac
     6481 taatgataaa agaataagaa tcataactgg tcactatgga agtggtaaaa gtgaatttgc
     6541 gatgaactat gttgttaagt taagagatat ggtttctggc aaagttgcta tagccgattt
     6601 agatgtggta aatgtatact ttagaactag agaaaagaaa gagttaatga aatccttagg
     6661 tatacaacca atagatagct caattaatgc tccaacatta gatttaccag cagtatcagc
     6721 agaggtaatg tctcctatgg tagaccattc atacaattct gttatagatt taggtggaga
     6781 taatgtaggt gctagggtta taggaagatt tagtcatttg ttaaaagaag gcgattatga
     6841 tatgcttttt gtaataaatg caaataggga gaaaactcaa acttctgaag aagttatcca
     6901 atatataaaa gaaatagaaa aatcttctaa attaaaggta acaggtctaa ttaataatac
     6961 tcatcttatt aggtttacta ctattgatga tgttttaaga ggtcagaaag ttgcaaaaga
     7021 agtttctgaa aaatgtaata taccgataag atatgttgca tgtttagaaa atcttgttga
     7081 acagttacca aaagatttag aaggagaaat ttttcctata aaattatata tgagagaaga
     7141 ctggatgtag tttgagctca aatatataga aagtttaagg aggcttaggt aaatggctaa
     7201 aggaaaagta tcttttaatc aagaacgttg taaaggttgt ggattgtgtg ttgaagcatg
     7261 tccagtaaaa atcatacaat tagactcaaa tgtaataaac aaaaaagggt ataacccagc
     7321 aactgttttt gaaatggaaa aatgcatagg atgtgcaagt tgtgcaacta tgtgtccaga
     7381 tgtagttata acagtagaaa gagattaatt taattaatat ttaaggggga attttaatgg
     7441 ctaagatact tatgaaaggt aacgaagcat ttggaaaagc agctatagaa gctggttgca
     7501 aatatttctt cggttaccca ataactccac aaagtgaatt accagaatat ttatcaagag
     7561 agttacctaa aataggtgga gcgttcgttc aagctgaatc agaagtttct gcgataaaca
     7621 tggtttatgg tggagcaggt gcaggagcaa gagttatgac ttcttcatct tcaccaggag
     7681 ttgctttaaa gcaagaaggt ataacatatg cagtaggagc agaagttcct tgtgttgtac
     7741 ttaatgtaat gagaggtggt ccaggacttg gaagtataca accttcacaa gctgactact
     7801 ttatgtctac aagaggtgga ggaaatggag actacagaac tccagtattc gcaccagcta
     7861 cagttcaaga agctgttgat atgataatgg aagcttttga cgttgcagat tattacagat
     7921 caccagttat ggtagttgca gatggtatga taggtcaaat gatggagcca gttgaattta
     7981 gagctcctga gaagaaaaga gaattgcctc ctaaagattg ggcaactgtt ggaactaaag
     8041 gaaaaagaaa acctaatgta ataaactctc tatacttaga gccagaagta ctagaagacc
     8101 attgttggca tttacaagaa aaatttgatg caatggaaaa gaatgaagta caatacgaaa
     8161 tgtacaaaac agaagatgct gaatttgtat ttgcagctta tggaactact tcaagagtag
     8221 taaaaagcgc aattgatata ttaagagaag aaggaataaa agcaggtctt ataagaccta
     8281 aagtattatg gccattccca ttcgaagcat tcaaccaaat tcctaatgct agaaacatat
     8341 tgactgttga aatgagtatg ggacaaatgg tggaagatgt taaaatggca gtagaaggta
     8401 aattaccagt ttacttccat ggaagaccag gaggaatgac tccaacacca gcagaaatag
     8461 ttgaaaaagc taaaaaaatt attgccggag aattggttgc aggaggtgct agataatggc
     8521 tgttgtattt aagaaaactg aaggattaca agatactcaa actcactact gtccaggatg
     8581 tacacatggt ataatccata gattagttgg tgaagtatta gaagaactag gagtattagg
     8641 tgatgctgta ggtgttgttc cagttggatg ttcagtttta ggatataaat attttaactg
     8701 tgacactcaa gaagctgctc atggtagagc gccagctgct gctacaggaa taaaaagagt
     8761 tcatcctgaa aatacagtat tcacttatca aggtgatgga gacttagctt caattggtac
     8821 tgctgaaata gttcatgcag ctgctagagg agaaaaaata actactatat ttgtaaacaa
     8881 tacaacttat ggtatgactg gtggacaaat ggctccaact acattagttg gacaaagagc
     8941 tactactgct caatcaggaa gaaatgctga aactcaaggt tatccaataa gagtaagtga
     9001 aatgttagct acattaacag gagctgtatt tgtagaaaga gtagcagttg atactccagc
     9061 tcatgttaga caagctaaaa aagctataaa gaaagcattc caagttcaac aagcaggatt
     9121 aggatttgga atagtagaag tattatctac ttgtcctaca aactggggac tagctccaaa
     9181 tgatgcttta caatggttaa gagacaacat gataccatac tatccattag gaaatttcaa
     9241 aaatgttgaa gttgaggagg tgaagtaaat gtctacagct agagtaatat gtgcaggctt
     9301 cggaggccaa ggtgttatgt ctatgggaca attacttact tatgcaggaa tgctagaagg
     9361 aaaagaagtt tcttggttac catcttatgg accagaaatg cgtggaggta cagcaaactg
     9421 tgcagtaact gtatctaatg agccagttgg ttctccactt ataacagatg atgcaactgc
     9481 agctatatta ttaaatatac cagcatttga aaaattcaaa gatgatgtta ttcctggtgg
     9541 aaaaataata gtaaatagtt ctttaataaa agaaaaagtt gatagaacag atgtagatgt
     9601 ttattatata ccagcaaatg aattagcagc tgaattagga aatgataaag ttgctaacat
     9661 gataatgtta ggcgcttact taaaagtatc tgatactgta gatatagaat ctgtactaga
     9721 agcattcaaa aaagttttcg gacctagaaa agaaaaattc gttccattaa acagagaagc
     9781 tttacaaaaa ggtatggatg ctacatgttc taaagcaact aactaataaa gaaaaagatg
     9841 tcaaaaaaaa gacaatagaa ttatttctat tgtctttttt gctgataagt attaaaatat
     9901 ttttatgact gaaattaagc ctataatgat attttatgaa ctataaaaat ataatacaaa
     9961 ttacaagctt ttcaattatg aaaggagaat ctttagtgag aaagtatttt ggaacagatg
    10021 gagttagagg agtagcaaat acagaactaa catgtgattt agcatataaa cttggtagag
    10081 ctggtggatt tgtcttagct caaggagacc acagagtaaa agtagtagta ggtaaggata
    10141 ctagaatatc aggtgatatg ttggaagcat ctttaatagc aggacttatg tctgttggat
    10201 gtgatgttat tactgttgga ataataccaa cacctgcagt ggcatattta actagaaaat
    10261 atggtgctga ttgtggtgtg gttatatctg catctcacaa tcctgttgaa tataatggaa
    10321 tcaaattctt taataagaat ggatataaat tagatgatga aattgaattg aaaatagaag
    10381 aatatataga cgatatagac aaaattgatt gtcttccaat tggtgaaaat gtaggaagaa
    10441 aattacatga acattgtgca caaagagact atgtagacta cctaaaatca ataataagca
    10501 ctgactttaa gggattaaaa gtagttttgg actgtgctaa tggtgcgtca tataaagtgg
    10561 caccaatagt gtttgatgaa ctaggagcaa gtgtaatttc aataaatagt ttaccagatg
    10621 gaaataatat aaactataaa tgtggctcta cacatccaga acaacttcaa agggctgttt
    10681 tggaacataa tgctgactta ggtcttgcat atgatggaga tgctgataga ttaattgcag
    10741 taaatgaaaa gggtcaaatt gttgatggag accatataat gatattgagt gccttaaatt
    10801 taaagaaaaa taataaattg gcacaagata ctttggtagt tacagttatg agtaatatag
    10861 ggttgacaat agctgctaag gaaaatggaa taaatttatc tactacagca gttggagaca
    10921 gatatgtttt agaagatatg gttaaaaatg gatataatct tggtggagag caatctggac
    10981 atatgatatt tttagattac aacactactg gagatggagt gcttagttct ctaatacttg
    11041 caaatataat tttgcaagaa aagaaacctt tatcagaaat tgcatcaata atgagccaat
    11101 acccacaagt attagtaaat gcaacaataa aaaatgaaaa taagaacaaa tatatggaat
    11161 atccagaaat aaaaactgag atagaaagaa tagaatctat tttagacgga aatggtagag
    11221 ttttgataag accatcagga actgagccat tagttagagt tatgttagag ggtaaagagg
    11281 aaggtcaaat aaaagaatta gcaacagact tagctaatct tatacaagaa aaattatcgt
    11341 aatttaaagg gtattctcag atacaaatac tgaggacacc tttctaagcg ccagaactta
    11401 gttatagaca taattattga gtaatatagg aactaagttg acgaggtcag agttaatcga
    11461 attgtcggcg gatgctctgc ggtgtgttta ccatcgaaag acttctttaa ataataggag
    11521 caatcctatg gacaaaggga agccaaagta aacttatatg acctaactct taaaatatat
    11581 aaataatatt tttaggagga cacaaataat gtgtggaata gttggatatt taggaagtag
    11641 aaaggcagca gaagttatag tagaagggct ttctaagcta gagtacagag gttatgactc
    11701 agcaggagta gcagttaata gttctaatga aaaagaactt aatattagaa agtttaaagg
    11761 tagactttct gtacttgcag aagacttaga aaagaatcct attgatggaa atttaggtat
    11821 agggcatacg agatgggcaa ctcatggaga accatctgat gtaaactcac atcctcattt
    11881 taatcaagcc aaaacaatag cagttgttca taatgggata atagaaaact atatggaaat
    11941 aaaagaagaa ttaatttctg aaggtgttaa gtttgaatct caaacagata cagaggtaat
    12001 agcacattta gtagataaat actatgaggg taatttatta gatgctgtat acaaaactat
    12061 atcaaaatta agaggagctt atgcattagg tgttatatgt aaagaacatg gaaatgaatt
    12121 agttgcagta agaaaagata gtcctcttgt agttggtgtt ggtgaaggtg aaaactttat
    12181 agcatcagat atacctgcat tattaaaata tactagagat gtttatttct tagaaaatgg
    12241 agaagtagtt catctaaaag acgaaaatgt aaccgtttat gactctaata gaaatcttgt
    12301 tgaaaaagaa gtatttcatg taacttggga tgtagaagct gcgtctaaag gtggatatga
    12361 ctactttatg tcaaaagaaa ttcatgagca accaacagga gtaagagaaa ctttagaaag
    12421 aagacttgat gataatggaa atataattct agacagtata aatatttcta aagaagactt
    12481 agaaaaaata aataaagttt atatagtggc ttgtggaaca gcatataatg ctggattact
    12541 tggtaagtat gccatagaaa aatttgtaaa tataccagta ataactgata tagcatcaga
    12601 atttagatat agcgacccat ttgtagatga aaattcatta gtaatattag ttagtcaatc
    12661 tggtgagaca gcagatactc tagcagtatt aagagattca aaggctaaag gagcaagaat
    12721 actttcaata actaacgttg taggttcatc tatagcaaga gaatcagatg atgtattcta
    12781 tacttgggca ggacctgaag tagcagttgc atcaactaag gcatatacta ctcaaataac
    12841 ttctttatac atgatagctt tagactttgc tatcaaaaaa ggaacaataa ctagagaatt
    12901 ttatgatagt atgatttcta agatgaaaga aataccatca aaaatacaag aaatactaga
    12961 caatgaagaa tatataaaag aagttgctaa aacagttgtt agttctgaac atgcattcta
    13021 tttaggaaga ggtatagact atagcttagc aatggaaggt tcattgaaat taaaagagat
    13081 ttcatatata catgcagaag cttttgcagc aggagagcta aagcatggaa caatagcttt
    13141 aatagaaaaa ggaactcctg taattgccat agctactcaa gaaaagttat ttgaaaaaat
    13201 ggtttctaat atggaagaag taagagcaag aggagcttat gtagtagcaa tagctcaaag
    13261 ccataataag gatgttgaga aagctgctga taaaataatc tatataccaa attcagatga
    13321 tattttatca ccaatattag cagttgtacc aatgcaatta cttgcttatc atgtctctgt
    13381 actaagagga tgcgatgtag ataagccaag aaatctagct aaatcagtaa cagttgaata
    13441 aaaacagatt aaaaattaaa tagataatat ttattgaaaa gaactcatcc tgttatttgt
    13501 attttatagg atgagttttt tagataaata ttaaatttgt tttgtttttg ctataataaa
    13561 ttttataaaa agattgatat taaatcatct gtaaaatgat aaatatatag accataccag
    13621 gtatagggaa cgataaatat agttcatata aaatatagtg agtacttaat aaacatatag
    13681 tcaatatcag ataaaaaaaa taatagctta tgagaaaaat taaaatacaa ggtattagta
    13741 accttgtgat aagataaagt gagtagttta aaataagaat ataaggaact atttataaaa
    13801 gaatataatg aagctaatag agtataagaa aattacttta ttttagtaaa ataatttcaa
    13861 ataaaaattt ttttaaattg ggagtataaa ttatgacaaa tgattttaaa aaagaaaaga
    13921 aagaagatta ttttgttaat cttaaggcaa tatctactga agttttacaa gaaaaagtgc
    13981 aagataacgc ttgggttata gttgatactc gcttaaatga tgcttataat ggctggaagt
    14041 tagatggagt aaaaagaggt ggacatataa aaggagcagt agatttttct gctaattggt
    14101 taagtgtata cttagataga aaagatgaag tgttagaaca agcattgaaa actaaaagaa
    14161 ttgatttaga taaaaatata gtattgtatg atgcaaatgg aaaagatgct ttggttgtag
    14221 cagattattt atctaaaaaa ggatataaat atctatataa atatgatatt aaacaatggg
    14281 cagacgacga aaatcttcca atggaaagat ataaaaatta tcaaatgata gttcctgctt
    14341 ttataataaa agatatatta gatggaaaaa ttcctgagac atttgaagat tcaaagaata
    14401 taaaaatgat tgaagcgagt tggggagaag aatcgtatac aaaagggcat atacctacaa
    14461 gtgttcatgt aaatactgat attatagaac ctcctccaac atggatgctt gataatgatg
    14521 ataacttaac taagtttgct ttagactatg gattaacaaa ggatgatact gtaatagttt
    14581 caagtagtac acctatggca tcttatagac tagctgttat attgagatat ataggagtaa
    14641 aagatgtaag agttttgaat ggtggaacaa actcatggtt atcagcagga tatgaattag
    14701 aatttattag taatccaaaa cattcatgta ctaattttgg agcagatata ccagttaact
    14761 cacaattagt tgttactaca tctgaattaa gacaaaaact aaaagaaaaa aataagttta
    14821 tactagtaga taaccgtact tgggatgaac atataggaaa agtatctgga tatacatatt
    14881 atgataaaaa agggcgtata ccaggagctt tatatggaca ttcaggtagt gatagtgttt
    14941 cactagaaga atatcgtaat attgataata caatgagaaa taaatatgag attttagaaa
    15001 tgtgggacaa ggaaaatata gatgtgaata aacagcttat atttatgtgt ggaagtggat
    15061 ggcgtgctgc tgaagtatta acatatgcaa atgtcatagg agtggaaaat acctcccttt
    15121 atagtgatgg atggatgggc tggagtcttg ataattcaaa tttaattgaa gtgggagaac
    15181 acaaataaag tttttgaaag tacaatagag ttgtttaaaa caaaggtgtt tttgatttat
    15241 taggaagagt gtgtaaattg tgtattggga agtggactta ggtatgttca tttggagcta
    15301 tggaaactga taaaaaagta ttatctgttt attttgctgg taaaatatga atagattata
    15361 gattatagat tatagattat agattataga ttatagatta tagattatag atttaagtat
    15421 agactaagta atttatatta cagaagagaa tatataagaa ttaatgcaag atgtatttga
    15481 tacatataag aaattggcaa gtccaggaga aggatagaga aaattgagat tgaagagttt
    15541 aaaagagatt attagatgaa aaatacaaaa atgtataaaa atacatattg agaaagtata
    15601 tctctcttaa atttgttaat aattctatta tacagaaaaa catatttaag ggggattttt
    15661 tactatgaaa aaagtaaaat tagctataag cttttttata ttaatgatta taggaatgac
    15721 aatatcttat gcagatacaa gtataaatac tagatacaat agattaagta aagctcttga
    15781 aatatcagaa gcaaatttta aattttataa tgttaaaatt aattctgtta taaatcataa
    15841 tttatcaaat aaagaatttc ataatatttt tatagaaata attaacaatc taaagttgga
    15901 taaaaaagga ataaattgga atcaaaaagg gtctggcgat aaaatacaat tatgtgctac
    15961 tataaaaggt agcgataaag aaatttctat aaaaggaata aataaaaata acaaagaaag
    16021 ttacatagta gttgacatat tggataacaa agtatataaa cataaagagg ttatttatag
    16081 taacgtagaa aatgtgttaa ataaatattc atctcaagta gatgtgtctg cttgtattgt
    16141 tggagaatac acaaaaaggt tacaaaacaa caaatatgat gatattttac aaaaaatatt
    16201 atataatatg agtgctaagc aaatagatga agttaaagac gtaaactttt tatctataac
    16261 agcatatagt aaagtattaa atgattatga attagaatat ttaggggaaa aaattaattt
    16321 aaatatagga attaaatata atgaggatga cggaaaaaca ctcatatata ttgccacacc
    16381 aattataaaa ttagattatt aattatgagg agatcaaaaa atatggctaa gataatagta
    16441 aaaaagagta atccacttaa aggtagtgtt aaaatagatg gtgcaaaaaa tgcagtttta
    16501 ccaataatag cagcgacttt attagcaaac ggaaaatcaa cattaaatgg agtaccaaat
    16561 ttaagagatg ttcatgttat atcagattta ttaagacatg taggagcaga agttgaatat
    16621 aaagaaaata cacttactgt tgatgcaagc aatataaaaa cttgtgaagc tccatatgag
    16681 cttgtaagaa agatgagagc ttcttttttg gttatgggac cattgcttgc tagatttaat
    16741 agtacgaaaa tttctatgcc aggaggatgt gctataggaa caagacctat agatttacat
    16801 ttaaaaggat ttaaagcctt aggtgcaaag atagaaatgg accatggttt tgttgaagca
    16861 gcaacagaaa agttagtagg aaataaatta tatttagatt tcccatctgt tggagcaact
    16921 gaaaacataa tgatggcagc ttctttagca gaagggacta caataataga gaatgcagca
    16981 gaagagccag aaatagtaga tttagcaaac ttcttgaacg aaatgggagc agatgttaaa
    17041 ggtgcaggta ctaatactat aaaaataaaa ggtgttaaag agttaaaagg agcagaacat
    17101 aatgtaattc cagacagaat agaagcagca acttatatgg ttgcagcagc tatgacaaaa
    17161 ggtgatataa ctgttgaaaa tgttttaatg gagcatttaa aaccagttgt agctaaatta
    17221 agagaagctg gttgtgaaat aacagaaatg gacaattctg taagagttgt aggtccaaaa
    17281 gtattaaaac caatagatat aaaaacttta ccacatccag gatttcctac agatgttcaa
    17341 gcacaattta tggctatgct tactgtagcc aatggaactg gtgtagttat agaaactgtt
    17401 tttgaaaaca gatttatgca tgttgctgaa tttaatagaa tgggtgctaa tataaaaata
    17461 gatggaagaa gtgcggttgt taatggtgta gatgagctac acggtgcagc agtaaacgct
    17521 actgatttaa gagcaggggc agctcttatt ttatgcggtc ttatagcaga aggagaaact
    17581 caaataggag aaatatacca tatccaaaga ggttatgttg atatagataa gaagataaca
    17641 gcactaggtg gtcaaatcga aatagtagaa gattaataat tggtttatag aagaaagtta
    17701 taaattaata gggttgttca tatacttaaa tacaaggttt taaaagctaa ggaggagagt
    17761 atatgaagaa cccattggtt gttttgttag gatttgtgac ttgctctgtg ttagttccat
    17821 cacttataac tttagtttct tataaaaatg tagaattaac tgaaaaacca gagagcccag
    17881 tatctataaa caaaactatt aaaaaaagtg atattgaaga caaaggtaat aaagaagaaa
    17941 aaaatacagt gaactatgaa actgtaaata aaaaagcacc aattatcaat gtatataatc
    18001 atataacagg gaaaaccgaa aagatggaca tggagaacta tttatgtgga gtactagctg
    18061 gtgagatgtc ttcagagttt gatatagaag ctttaaaagc tcaatctgta gcagctagaa
    18121 catatgtagt atataaacag gaacatggta aatctagtaa acataaaaat gcagtagtat
    18181 gtactgatta taaacattgt caagaatata agagttatga tactcttaaa aaattaaatg
    18241 gtgaagaatg gattaagaat aaatattcca aaatccaaga agcagttaga ggaactaaag
    18301 gtcaaataat aacttataat gataaggcga tacttcctct ttatttttct acatcttcag
    18361 gaaaaacaga aaatagtgaa gaagtatttt ctgcaaaata tccttattta aagtctgtgg
    18421 aaagtcctta tgataagtat tcccctaaat ttgcgtcaac acttaaaata agtaacacag
    18481 attttgttaa aagtcttaga agggcatata gcactattgt gatagatgtg aataatttaa
    18541 gtaaacaagt ttcaataact aaaagaagtg atgccggaac tgtagaaaaa ataaaattag
    18601 gaaataaaga attgactgga aaagacatta gaactgtttt taaattgaac tctgcaaact
    18661 ttgacataaa atttggagaa ggatacatag atttcgtggt aaaaggatat ggtcatggtg
    18721 ttggtatgag ccagtgggga gcagaaggaa tggcagaaga gggctataaa tattatgata
    18781 tattatcaca ttactacaca gatacaaaaa taaaagatat atactaataa ttgtataaaa
    18841 tgccaaaaac acgtcaataa tccaaatgta gaaatatatt tggaggtgca aaatgaagaa
    18901 aaagctgtta gaaaaagatg gtttttattt atctttgttt gtatgtgttt gtttattagc
    18961 agtaggtgga gtttggttta caaataataa tgtagataaa ttggcttcta ataaaggaat
    19021 tatggaaaat gctaataaag atagtgaaga ggaaatacat ttaattgaaa aagacaagaa
    19081 agatgctatc cctactgcaa cggattcaaa acaaaactta gaaaaagcta agtcaaaaga
    19141 ggaaaataaa tcgagtacaa caaaattaaa ttacattgga gataaagtaa taagaggata
    19201 ttcagaaaaa gagcctagtt attctaaaac acttgatgtt tgggaaactc ataaaggtgt
    19261 agatattagt tgtactaaag gcaaagaagt aaaatctcta ttaaacggaa tagtagtaga
    19321 tgtatttgat gatgaagaat atggacaatc agtcaaaata aaaagtgaca ataacattgt
    19381 agtagtatat tcaaatctag ataaaaatgt tagtgttaag aaagaacaga aggtaacaga
    19441 aggacaatct ctaggtactg taggtagtac ttctcaaata gaaagtgaag aaggtataca
    19501 tgtgcattta gaggcgtata gtggagaaaa atctatagac ccaatgagtc taattaagta
    19561 atagtataac aagtttaatc atatttggtt aagcttgtta tattttttgg tgtttttaca
    19621 tatatatcat taaagctatt atgtgagggg ggtaatcttt gagatctcat atagaggaaa
    19681 gggccatagt ggtagcaaaa tatatacttg aaaaaaacac tacagtaaga caaaccgcca
    19741 agacatttgg agtaagtaaa agtacaattc ataaggatgt tacagaaaga ttgaaggaaa
    19801 taaatccatc ccttgccaaa gaagttaaaa atgtgctgga caaaaataaa tcagagagac
    19861 atattagagg gggattagca acgaaattaa aatatgagaa ggaacataaa aaaatgtagg
    19921 ttaaaaacct acttttttta ttgaattaaa ttataaaaag aaatatatta agtaattata
    19981 aatagcaaaa taataatact ctcaaaagat ttattttctc ttgattaaag cgagattttt
    20041 gtatatgctt tattatagga gtattaaaat aggcttataa tataatctaa tattataaat
    20101 aaaggagttg aaaaaatggc tggagctgat ataggcatag atttaggtac tgcaaatgtg
    20161 cttgtttatg ttagtggtaa gggaatcgtt ttagaagaac catctgttgt ggcgatagac
    20221 aaaagaacag attctgtttt agctgtggga gaagaagcta aaaagatgat agggagaaca
    20281 ccaggtaata tagtcgctat aagaccttta agagatggtg taatttcaga ttatgatgta
    20341 actgagaaga tgttaaaatc ttttatagat aagatagttg ataaaaaggg atttggaaga
    20401 ttttttatgc caagaattat ggtatgtgta ccaacaggtg tcacagaagt ggaaaaaaga
    20461 gcagtagaag atgctacgag acaagctgga gctagagaag tatatatcat agaagaacca
    20521 atagcagctg ccataggagc tggtgtagac atatcacagc ctaatggtaa tatgattata
    20581 gatattggtg gaggtactgt agatatagct gtaatatctc taggaggagc tgttgtaagt
    20641 gaatctataa aggttggtgg agatagattt gatgatgcta tagttaaata tatgaaaaaa
    20701 caacacaatc ttcttatagg agaaagaaca gcagagaaaa tcaagtttga aataggttct
    20761 gcatttaaga gagaagaaga aaaatatatg aagataacag gaagaaattt aattacagga
    20821 cttcctagtt ctataactat aaattcaaca gaaatgttgg aagcacttag agaatgtgtt
    20881 gagcaaatag tagttgctac tcatgctgtt ttggaaaaaa cgcctcctga gttagcagca
    20941 gatataggag atgtcggtat aataatgact ggaggaggtt cattattata tggattagat
    21001 aaaataatag aacagaggac aggaataact gttacaatag cagatgaacc attatcttgt
    21061 gttgcaaaag gtacaggaat agctttaggt tcaatagact tacttgaaac tggtgggtct
    21121 ttcaaaagaa aataattagg agagtttaga atgttaaata tagatgaaat aaaaaaatta
    21181 ataccacata gatatccatt tttattagta gacaagatta cagagctaga agttgggaaa
    21241 agagctgttg gtataaagaa tgtaacagtt aatgagccat ttttccaagg tcactttcca
    21301 gaatatcctt tgatgccagg agtactaata gtagaagctc tagcacaagt atgtggagtg
    21361 gcaatgatgt ctgtagagga aaacaaagga aaactaggtg tatttgcagg tatagataaa
    21421 gttagaatca agagagaagt aagaccagga gatacattaa ctatggaagt tgaaatgaca
    21481 actcttagaa aaaatatagc taaggcagat gctaaggcat atgtaggtga agaacttgtc
    21541 tgtaaaggtg aattaatgtt tgctttagta gaaaaataaa aacttgaaat ataaaagtaa
    21601 aaaggtagat aatttggagt atttaatcag atactctaaa atatctacct ttttatataa
    21661 agaattttat catttagttt atatttagat taggtggata ctaataaagc caaggctatt
    21721 gtttcagcta aatctaatat aaagctaagg cgtatattat taaatgaaag tttattattt
    21781 tcatcaattt tatctacaat tcctactata gaataatttc ctatttgagg tagtttttta
    21841 ccaacacctt ttccgggcag gataggtcct tctctaatct gtatattacc tatgttactc
    21901 tgcgacccca agcaagcatc tatagccaag aagttacctt gtatatgtgt attttttata
    21961 gtatctaaag actcatatat atttaaggcg tgaatagggt tatctagtgt accgtaaacg
    22021 gggtatttaa agttactgtt cttaagtatt gttccaacta aagggcctaa agtatcacct
    22081 atagccctgt ctgttcctat gcaaacaaca atcgtatttt cattaattat agtttttaga
    22141 actgaactta gcatctgtat aacatcatca tcgctgtagt ttactttagc taaatacaat
    22201 aggaacaccc ccttcaaaaa aatatatgaa taaaaagcat taaaaagacc taactttaaa
    22261 tttcagatag atagaaaatt ttatttgtct tacaaaaaaa ggaatagaaa aaatatgact
    22321 aaaaatattg acaaaatttt aaaaaaatag taagctagta aagtaaaaca aaacttaaat
    22381 cttgattacc ttatcaagag aggctgaggg ataggccctg tgaagcccag caaccaccca
    22441 aatgggaaaa ggtgctaatt cctacaagac aaaagtcttg aaagatgagg tcagttaatt
    22501 agtatgtaat tacgattatt aacctcttct tataaaggag aggttttttt attttgagta
    22561 aatttctaaa attaaaaata aggtaaaacc tataataaaa attaagaata aataaggggg
    22621 aataaaaatg gcaagacatt tatttacgtc agaatcagtt acagaaggac atcctgataa
    22681 gatatgtgac caaatatcag attcaatatt agatgcatta ttagaaaaag acccacaatc
    22741 tagagtagct tgtgaaacta cagttactac tggtttagtt ttagtagcag gagaaataag
    22801 tacatctgct tatgtagaca ttcctaaatt agtaagagaa acagtaagag aaattggata
    22861 tacaagagca aaatatggat ttgattgtga tacttgcgca gttataactt ctattgatga
    22921 acaatctgga gatatagcta tgggagttga tgaaggtcta gaaagtaaga ctggagaaga
    22981 gatagaagaa gaaatagaaa aagttggagc tggagaccaa ggtataatgt ttggatttgc
    23041 atgtaatgag actccagaat taatgccact tccgatatct ttggcacata aattatcaag
    23101 aagacttaca gaagttagaa aaacaggttt agttgattat ttaagaccag atggaaaaac
    23161 tcaagttact gttgaatatg aaggaagtaa agctgtaaga gtacatacag ttcttatatc
    23221 agctcaacat tgtgaaacag tatcaaatga taaaataaga gaagatttaa ttaatcatgt
    23281 tattaaggaa gttataccag cagaattact tgatgaagag actaaaattt atataaatcc
    23341 aacaggaaga ttcgttatag gaggaccaca aggagataca ggtcttacag gaagaaaaat
    23401 aataatagat acttatggtg gatattctag acatggtgga ggagctttct caggaaaaga
    23461 ccctacaaaa gttgatagat ctgctgctta tgcagctaga tatgttgcaa aaaatattgt
    23521 tgcggctggt cttgcagaca aatgtgagat agaacttgca tatgctatag gtatagctag
    23581 accattatct atatttatag atacttttgg gacaggcaag gtttcagaag aaaaacttgt
    23641 tgaattagta aataaacact ttgatttaag accgggagcg ataataagag acttagattt
    23701 aagaaagcct ctttataaaa aggttgctgc ttatggtcac tttggtagaa ctgatataga
    23761 tttaccttgg gaaagaactg acaaggttga gcagttaaga aaagatgctt taggtgaata
    23821 atttttaact aaaaagctgt tagaatgtaa ttttatgatt actttctaac agctttttta
    23881 ttatgagtta aatattttta ataaatgtta atttatcatc atataatgaa taaacagtat
    23941 ttaatctggt caatacattt tatataatac tctactaaat ttatacatat tatgggatat
    24001 atgttaaaga atggttaaga atgtgttaac taatgttaaa taattaaaaa tatattgaaa
    24061 tatcacaata atgagtctaa tataatctta ataaacttac actttaaaaa taattttaat
    24121 tgggggggag tagtgtatgt caggcaaagt aaatattaaa acggttataa gttttgctgg
    24181 agcttatgtt gctactgtaa taggttctgg atttgcaact ggtcaagaaa tactgcaatt
    24241 ttttacgttt tatggatatg cgggtattat aggtggaata atctctatgg tactattttc
    24301 atggtttgga gcagaagtta tagataaggg aagagaattg aaacttaagg agccaataaa
    24361 aatttatcaa gtatattgtg gaaaatatct tggaacattt tttgaatggt ttggtccatt
    24421 gtttttattt ggaacattag taataatgat tgcaggagca ggagctacat tatcagagta
    24481 ctatggatta aatccatatg taggtaggat tggtatggca atcgtttccc taataactgt
    24541 ttcattaggt ttgacaaggc tttctaaaat actaggtaat ataggaccta taataataat
    24601 atttacactt ttagtaggag caattagttt atttagcaat attgatgctt tatcaaatgc
    24661 tggaaatatg gttgatagtt taaatattaa aactgctaca tcaaatggat atttctcggg
    24721 agtactttat acttgttaca atgtaataat agtaataaca ttcttgacag gaatgggagc
    24781 ttctgcagta aataagaaag atgctgtatg gggtggtata gtaggtggag tagcacttat
    24841 ggcagcagct ataatgatga atttggcatt actttcagac ataggaaata tatacacaaa
    24901 agagatacca gcactttact tagctgataa gatatctcca gtaataggta ttttattctc
    24961 agtagtactt ttactaggaa tatacactac agctgtacca ttgttatggt cagtaacaaa
    25021 ccgatttgta gaagatgacc accctaagtt taaaattata acaatagtgg taagtatatt
    25081 agcttgtata ggaggtttac tgccatttga taagttagta ggtacactat atccatatac
    25141 aggttacatg ggaattttaa ttttactatg tatgctttat agaagaatta ctaaaactga
    25201 ggggtacaag gagaataaat ctgaaataag ttagtactgt aatatactta tgaaatttaa
    25261 tttatactct aaatatagag taattaaaat aaaatagcta tttaaatatg gtacctgtat
    25321 ttcatggtac catattttat ggatgcagat tttttttgtt tctgataaaa tgtataatag
    25381 ttggaaatta cgttaagtat aaaaatataa aacttttcta cgattatcat ggttttaata
    25441 tataaaatta tactaacatt taaatggagc gattattagt atttttagga gataaaaatg
    25501 gaaaaattag aaggaatgat aagtgaaata gtctttaaaa acgaagacaa tggttataca
    25561 atagctcacc tggtaaatga aaatgatgaa attgtggttg taggatgtat gcctactttg
    25621 gcaattggag aaagcataga agttgaagga aagtgggtaa atcataagat ttatgggact
    25681 caatttgaag tgaatagttt tatgccagta acaccatcat ccttagaagg aatttatgtt
    25741 tacttatctt ctggaatgat acatggtatt ggtgaaaaaa tggcaaaaag aataattgat
    25801 aagtttggtg tagatacgtt agaggtgata caaaattcac cagaaaaact acaagaagta
    25861 gaaggtatag ggagtaaaaa agtaaaacaa atagtaaaaa gttatgaaga agacagagaa
    25921 ttgagaaata taataataca gctatctcct tttggaataa caccaaatta ctgcctaaaa
    25981 atatataaaa aatataaaag cagtgcaata gaagttataa ataaaaaccc ataccaactt
    26041 gctgaagata taagaggaat tggatttaaa gtagctgata gtatagcaag taaaattggt
    26101 atagataaaa actctaaaga tagaatttgt cagggaatct tatacacttt aaataaatct
    26161 ttaagtaatg ggcatacata tttaccagag catgttctaa tacaagattc ggaaaaattg
    26221 ttggagctaa atggagaaat actaaaagag tgtgtaatga tgctagttta taatcaaaaa
    26281 atacatatag agaaagtaaa caatgaaaat cttatatacc ttatgccata ctatttagct
    26341 gaaaatggag tatgtagtca aatagtaaaa ttatcacagt atgaatttga agacttaaaa
    26401 atagatatag ataacgagat taatgtttta gaagaagata agaaaattaa gttagcagaa
    26461 aaacaaattt tagcagtcaa agaatctgtt aatagtggag tattaattat aactggtgga
    26521 ccaggaactg gtaaaacaac taccattaat gctatcatag atatatttga aaataatggt
    26581 aaaagtgtga ctttggcagc tccaacggga agagcagcaa agagaatgag tgaaacttct
    26641 aataaagaag caaaaactat acataggttg ctagaaatgg gattttcaac agatgatgat
    26701 ttaacttttt ttaaggatga agaagaccca ataaattcag atgtaataat tgttgatgag
    26761 gtatcaatgg tagacattat cttaatgtac aatttactta gagctataaa gttaggaaca
    26821 agagtaattt tagttggaga tagtgaccaa ttaccttctg taggtgctgg aaatgtactt
    26881 aaggatatga ttaattctaa tattataaat gtagttaaat taaatgaaat atttagacaa
    26941 gcgcaagaaa gtatgataat tgtaaatgcc cataagataa acaatggaga accactttat
    27001 ctaaatacaa aaggtaaaga tttctttttt ataagaaaat caactaatga agaaatttta
    27061 aatgaaataa taggattggt taatgaaaga ttacctaaat tttataaagt tgataaatta
    27121 aaagatatac aagttttatc ttcaatgaga aaaggtgaat tgggagttac taatctcaat
    27181 atagagttac agaagtatct taacaaaaaa gaaaaattta aagttgaaga aagtttttct
    27241 aaaagattat ttagagttgg cgataaggta atgcaagtaa aaaataatta tacaaaaaaa
    27301 tgggaaacag aagaccaaaa agaaagtgga gaaggtatct ataatggaga tataggatat
    27361 gtttatcaca tagataaaga taagaaaact atttatatat tatttgacca gactaaaatt
    27421 gtatcatacc tatatgatga attagatgaa attgaccata gtttttgtac aacaatacat
    27481 aaaagccagg gaagtgaatt tccagttgta gtattgccaa tagcgtgggc tcctcctatg
    27541 ttacttagcc gtaatttatt atatacagca gtaacaagag caaaaaaatt agttgtatta
    27601 gttggagatg tgaaatatct tgaatatatg ataaaaaata atagagttaa tcaaaggtat
    27661 tcaaatttag gatataagct aaataaattt aaacaagaag ggttgttgat agaataaata
    27721 tgaaaatatg caatgataat tttattaaga attttaaaaa tatgattaat aaatgtttgg
    27781 attttatata tcctgagaat ataagttgca taatttgtga taaatccata aagaaaacaa
    27841 atacttattc aatatgtaaa agttgtttta aagaaatgaa ttttatacaa gatggttgca
    27901 tgaagtgtgg aaaaccaata atacgtcatt caattgaaaa agaatttatt gaagagtgta
    27961 gttattgttt taataaagac ttttattttg ataaatcaat atcttgtatt gaatacaatg
    28021 atgtgacaaa aaagatggtg ttagggctga agtataacca aaaaaccttt atggctaagt
    28081 atatagctca aataatgaaa gaaaaattat atttagaaaa cataaaattt gattatatat
    28141 tatttgttcc acttcataaa aaaaggctaa ataaaagagg ttttaatcag gcacaaaaaa
    28201 tagcatttaa tttaagtaaa atagtaaata ttccattatt agattgcata agtagaaaaa
    28261 aatatacaag aatgctatat aaattgaata agaaagaacg aaaagaagaa ttaaaaaatg
    28321 tatttgttgt taaagaaaat gttaaattaa taaataataa aaatatactt ttaatagatg
    28381 atatatttac tactggtcta acaacaaacg aaatttctaa acttttaaag ttatcaggtg
    28441 ctaataaggt ttttatattg actctactta caaaagcaaa tgataattat attatggaat
    28501 aatcttatat attgacaatt ttagtttaaa atattaaaat gaataagtga tatttaggtc
    28561 tgtggttgaa agtccaagcc agtcgcaggc aaagggatcc acgtaagtta acactaaaaa
    28621 ttgggttaat gatcatggtg cggcttagaa gtaagaccta ccgataataa aatcgagaga
    28681 gagtagtagt gcggcgaacc caagcgaacc ctccagtagg cgagtgtggg gtcaaaaacc
    28741 aggtcagcta aatatcatat taaaagagag ctagcatacc tttatgtata gctctttttt
    28801 atatataata aatttaggtt gagtcataaa gaggtgatat gtttgaataa aagacaagaa
    28861 aatttattaa caacattgct attaaaagaa gagtttataa atgttaataa gattgccaat
    28921 gattttgagt gttcagaaag gacaataaga aatgattgca aatatattga tgaatggtta
    28981 tctacttttt gtaatgctta tatcaaaaga aaacctaata ttgggattaa atttagtgga
    29041 gatggaacag acaaaatact ggtaaatcag aagttgcgag gtgaagttaa aagagtaaat
    29101 agtgagcttc ataagcaagt tgagatatta aatttactac tttgtaataa taaaaaagtt
    29161 actttaaatg atttatctaa taagttgtac ataaataaaa atattgtcag agaagaaata
    29221 agtaaattat cagtagcatt aaataattat aatttaaata tctcgactaa aaaaggcagt
    29281 ggtatatata ttcaagggga tgagaaagac ataagaataa tgttagtatc attcttattt
    29341 aaatatatag ataaatacag attaaacata gatgaaatag agtacttcca tatagtagat
    29401 ataataattg taaaaaacat aatgcttact atagaggagg acatggatat aagacttaca
    29461 gatatatcat tcaaacaatt gatgctattt ttgcttataa atataatacg aataaggctg
    29521 ggaaattctt taaaagtatc aaatactaag aaagagctta agctaaaaat gcttatattg
    29581 gatatagaag atgaattgaa atctaattta tccatagtat taaattatga agaaaaattg
    29641 tttatagaat ctttaatatt gggtatgaac aaacaaataa atagtaataa tattaagaaa
    29701 tctttatatc taaatgaaga attagcaagt tatacaaaaa aaattataaa tttagtatca
    29761 gaagaatcag gaataaattt taataatgat atattacttt atgaacaatt aatatgtcat
    29821 ttgaatgtta caatgcatca aatgaaaagc aatgtttact tagaaaatcc acttttagat
    29881 aacataaaaa ctaaattttg ttttttattt acagtaatat caagttcaat agaaattgaa
    29941 ttaaaaggaa aacaaataac ggaagatgaa attggttatc ttacacttca ctttcaaacc
    30001 tctctagaaa gaaaatacag caaaagggaa tcaaataaaa aggcaagtat tgtatgtcca
    30061 tttagttttg gagtaagtat gctattaaaa gtaaagatag aaaagagatt tgataatata
    30121 aaaattattg aaacattaag agaggaagat ttaaaaagag ataacttcaa taagactata
    30181 gattttataa ttgcatttca agagtatgaa aatatccaaa aaccaatttt tataacaaca
    30241 ccattattta ctgatgagga tgagaataaa cttaaagagt tcacaaacaa aataaaagaa
    30301 aaagacactt catataaact tatgaacaga ttaatgatgt ctgattattt aataagagag
    30361 ttagaacatg atgatattta tgaagctata acatatttaa ctaatttatt aattgaaaaa
    30421 cattatgcag aaaaagagta tttacaatct attataacaa gagaaaagtc atatccaacc
    30481 aatgttggaa aaggaatatt attccctcat ggagacatga aatatataaa acaatctgtt
    30541 ttatgttttg caaggttaaa aacaccaata aaaattagaa atggaaagga tataaagatt
    30601 atacttttgt tagcatataa aaaagatgat gatagaaaag tatttagaga attatttaaa
    30661 gaaatatcta atttaacaga ggatgaaaat atgctagata ttctaagtaa atgtgacatt
    30721 gaaaaggtaa aagatattct tatataaaat tcatagtgaa ctatggataa gcacaaaatt
    30781 ttccatgtga tggaaaaagt tgtgcatgtt tttttgtttt tataagatat tatatgtttg
    30841 taaggtataa ataatctaaa agtagagaag caacttagga ggaaaaaatg gaagaaatag
    30901 ttttaaagat tataattcat gctggaaatg caaaatctat gctttatgaa gcacttgact
    30961 atgcaaagga aaacgatttt aaaaaagcag atgaattaat tgaaaatgca aatgaagaaa
    31021 ttttaaaagc acataaagta caaactgaac ttatacaaaa ggaagctggg ggagataaat
    31081 cagatatatc tattttattg attcactctc aagaccattt aatgacttgt atgagtgaga
    31141 gaaaccttat aaaagaaatg attatgttaa gaaaagaaat tcaaaaatta aaataaaaaa
    31201 attaaggggg atttaaaaaa tgaaaagaaa agtatattta ttttgtagct ttggtatgtc
    31261 aacaagttta cttgcagata aaatgcagaa ggtagcagat gaacacaatt taccaataga
    31321 agtagaggca tttccgatag cagaaattga caaaatagtt gaagaaaaaa atccagattg
    31381 tatattatta ggaccacaag ttaaatacat gctaaaggag ttaaaaccaa agtttgaagc
    31441 tcaaggaaaa cttatagata taatcaatga agttgattat ggaactatga atggggaaaa
    31501 agtattaaag cttgctataa agctaataaa atctaaacaa gcgtagaatt atagtaaaaa
    31561 ataataggaa atgagggtgg atagatgaat agattggaaa gaatacttat gccattggct
    31621 gaaaaaatag gtaaaaataa attattaatt gcaattagag atggtttttt agtatcatca
    31681 ccattattaa taataggttc attattttta ttagtagcaa attttcctat aaaaggatgg
    31741 aatgaatttg taggtcaaat ttttggtcca gattgggctg taaaattgca acaaccaact
    31801 gtagcaacat ttgaagtaat gactctactt gcagttttag ggattggata ttcttatgca
    31861 aagcaaatag atgtagaccc aatagcatca gcagcagttg caatagttgc cttttttata
    31921 ataacaccat ttgtaatacc atatacacca gaaggaacgg aatcagttta catggtaaca
    31981 ggtataccac taggttggat gggttctaag ggaatgtttg taggtatgat aacagcaata
    32041 acctctgtaa aattatttgc tgcagttgta aaaaaaggat ggacattgaa aatgccagat
    32101 ggagttcctc caactgtatc aaaatcattt gcagcattaa taccaagtgc aatagttatg
    32161 gtagttttct ttttagttaa gatagctttt gaagctacac catatggaag tatacatgaa
    32221 tttatattta agtttttaca aatgccatta ttaaaattag gaaatagttt aggtgctatg
    32281 gcaatcgctt atatattctt acatttattc tggttctttg gaataaatgg aagtagtgtt
    32341 gttggggctg tgtataatcc aatattaaaa attctatcag ctgaaaactt agctgctttt
    32401 caagctggtt caaaaatacc aaacataata acaggtcaat tccaagatat gtttgcgaca
    32461 tttggtggag caggtagtac actatcatta gtcatagcta tgttattaat atgtaaaagt
    32521 aaacgtataa agtcaatggg aaaactatca attttaccag gaatatttgg tataaatgag
    32581 ccattgatat ttggtctacc aataatgctt aacccaatac tattgatacc atttgcaata
    32641 gttccaacaa taaatataat aatagcttac ttctgtatgt cagcaggatt agtgcctctt
    32701 acaaatggag ttcagttacc gtggacaact ccaattatat tctctggttt tttaacaaca
    32761 ggatggcaag gtgcagtctt acaattagta cttcttatac taggaatatt tatgtatata
    32821 ccatttataa aaatgctaga taagcaatac ttgagagaag aaaatgaaac tgttgaagag
    32881 gaagatgatg atatatcttt tgatgattta gtattatagg aggaagatta tgaagaaaat
    32941 agttatgata ttggaccaaa tacaagctgg agctggagga aaagagaaaa gtaatatacc
    33001 tcctgctgga aaatcaagcc cattaggacc aggtgtaatg atggagcaat ttttaaatga
    33061 atctaaggta atagctacct tattttgtgg ggatgaattt tttgtaaata atcaagaaga
    33121 agtaacgagt aagatgatag ctatggtaaa aaaattaaac cctgatgtag taatctgtgg
    33181 accaagcttt aattacgaaa acttttctaa gatgtcagca atactgtcta aaaatataaa
    33241 tgataaaaca gatataccag cttttgcagc tatgtcagaa gaaaatatag atgtgataaa
    33301 cgaatataaa aatgacatat gtatagttaa gactccaaaa aaaggtggaa ttggtcttac
    33361 tgattcgtta aataacatat gtaaattggc aaaagcaata gcaaataaag aagatataac
    33421 tttgatgaaa gaagaatttt gttattaata agagtattaa ttattagcaa gtttaaatat
    33481 tatactattt ataataagca tacattagta aaatctatat aatttaagga ggggaatttt
    33541 aacatgtggg gaatgatagc gacatggaga atggccctag aaggaataac tgaggcatca
    33601 gaacatttag aaaaaggcat ggaagcaggt gatgctgtag agcttgctgt aagaagggtt
    33661 gaagactatc cattctataa atcggttgga tatggtggac ttccaaatga aaattgtgag
    33721 gtagaacttg acgctgcatt tatggatggt aacacattag atattggcgc agttgctggt
    33781 ataagagatt attctaatcc tgtcagcata gctaggaagt taagttatga gaaggtaaat
    33841 aattttttag ttggaatagg tgctgaagat tatgctcata aaaatggatt tgaaagaaaa
    33901 aatatgttga ctgatagagc gaagttacat tataaaaaga gaaaaaaaga gactttagac
    33961 aaaggattaa gcccatatgc tggtcatgat actgttggta tgatatcttt agacaaaact
    34021 ggaaaaatgt gtgtagctac atcaacaagt ggattgttta tgaagaaaag aggtagaata
    34081 ggagattctg cactatctgg ttcaggattc tatgttgata gtagtatagg aggagctaca
    34141 gctactggtt tgggagaaga tttaatgaag ggatgtatat cttatgagat agttagactt
    34201 atgaaagaag ggaagcatcc acaagaagca tgtgatattg cagtaaatga acttgataaa
    34261 cagcttatca aaagaagggg aaaagctggt gatttatcat tagttgccat gaataataaa
    34321 ggtgaatggg gagtagctac aaatatagct gattttactt tttcagtagt aactaaagaa
    34381 gaatctccta ctgtatatat ttcaaataga gtagatggaa agactataca taaggttata
    34441 tcaaatgagt ggatggaagc atatgaggct agaataaaag caccaataga agtaagtgag
    34501 taaagtagtg gttacataat taaaatagag ttttataata aggagatttt tatgaatatc
    34561 ataagtaata aaatagatga gttaaaagaa gatttattaa gtgatattat agatattgta
    34621 aaaataccta gtgtcaaagg ggagtcagaa aatggcttcc cttttggcga aaaagtaggg
    34681 gaggcactta ataaagcatt agaaatatca gaaaaattgg gatttaaggt tagaaacttg
    34741 gataattata ttggttatgc agagcatgga gatagtgatg attatgtttg tgtaattgga
    34801 catgtagatg ttgtacatga aggagatggt tggaagcatc agccttataa gggagaagaa
    34861 actaatggaa gaatttatgg acgaggagta ctagacaata aaggacctat aatgtctgcc
    34921 ttatatggat tatatgctat taaagaatta aacttaaaat tagataagag agttagaata
    34981 atatttggta caaatgaaga aagtggattt gaagatatac catattattt agaaaaagaa
    35041 aaagcaccta ttatgggatt tacaccagat tgtaaatatc ctgttgtata tggtgaaaaa
    35101 ggcatggcaa agattagaat aaaaagtaaa atcaattatg aagaagatgt atacctaggt
    35161 tttatagaaa atatgtctga aaatgtgctt gttacatata aagaactgaa tatagaaaat
    35221 agtgatacta tattagatat aaaggtaaaa tacgatttta gttataaatt gaaagatgta
    35281 ttagatgaaa taaaagctag ttttccaaat agtatcgata tagaggtaat ttctaatttt
    35341 aatcctgtat attttgataa agagagtaat cttgttaaaa agcttcagct agcttatgaa
    35401 agggttacat cattagatgg aactccagta acaactaatg gaggtacgta tgcaaaagta
    35461 atgccaaata tagttccgtt tggaccttca tttccaggac aaaaaggaat agctcataat
    35521 cctgatgaat acatggatat agaagatata atattaaatg caaagatatt tgcaaatgca
    35581 atatatgaat tagcaaagga gtagttatgt tagaaataat aggaatgtca gtagaagacg
    35641 ctaaaattat agaagattgt ggtgcagata gaatagagtt agttagtgct ttaactgaag
    35701 gtggattgac accaagtttt ggtcttatag aaagtgttgt taacagtgta aagatacctg
    35761 taaacgtaat gataagacat catgcgaaaa gttttgtata cagtaaagaa gatataagta
    35821 taatgcaaaa agatataagt gtggttaaag agattggtgc taatggagtt gtatttggtg
    35881 tattggataa aaacaacaat atagatgaga aaaatctaaa tgttttattg aaatgttgtg
    35941 ataatcttga tgttacattt catagagcca tagatgaatc aaatacaata gatagtgtta
    36001 aaattttgaa ggattatgat aaaattacga atatattaac atcaggtggg aaaggaagta
    36061 tagttcataa catacaaatg ataaaaaata tgatgcttag ttctaatcac ataaaaattc
    36121 ttttaggtgg aggtcttaat tttaataata tagaaaagat aaaggaatta actaaggcaa
    36181 gtaattttca ttttggtaca gcgattagaa taaataacag tccttttgaa gatatagata
    36241 gacaaaagct taaacaactc gtaaatataa tttcaagata gtatatgaat ataaaatact
    36301 tagtttaaat aaagagagta agttaattat aatttgggta tatgaatgtt aataggtatt
    36361 aaatatgaaa ttattgttga gtatgcttta taacttttaa gtagttttaa atataaataa
    36421 tgaaagaaaa gatagattat ggaggtttta gagggtttat atttattaaa aaattataaa
    36481 ggtatattgg catataatac acataatttc ctaaaattac catcttatga catgaattca
    36541 catattaata aacaattaat ggagattttt gtggatagaa ataggagtaa aaatagcttt
    36601 aaataaacaa aaacaagagt tattaacagt tttatccaca ttatccacag gtgtttgtaa
    36661 taatattaat ccacataagt atcaatgtaa ctaaaaatga taaataattc tatcaattga
    36721 atagaaaaaa tcataaaagt aaataataaa aagaggatta tgagagttcg tgtagaatat
    36781 attattaaag tataaatttt cttatactgg cataattgaa gggagatgta tttatgaaca
    36841 taattatatc tggaaaacaa atcgaattaa ctgatgcaat aaaaaataaa atcgaaacta
    36901 aactaagtaa gttagataat tacattcatc cagacactga tgtaaaagtt acagtaagtg
    36961 cgagaaaagc aagacaaaaa atagaagtaa caatagctac tgtaaatggt cctataatta
    37021 gagcagaaga tatgcaggaa aatttataca cagctataga tgttgtatat gataaattaa
    37081 gtaaacaatt aaaaaaatat aaaaagagat tacaagataa acataaagac aacaagagta
    37141 taagattcca agatgcagag ataaatctag ctgatgaaca agaggattat ggggatgaaa
    37201 atcaagaatt agtaattcaa agacgtaaga aatttagtgt taagccaatg agtgaagaag
    37261 aagctgtatt acagatggaa ttaataggac atgattttta tatgttcaag aacatagatt
    37321 cagatgaaat agcagtagtt tataagcgta ataatggtgg atatggtata atagaacatg
    37381 aataaagcaa tttagattta atcatattag ctatcgataa ataaattatc gatagctttt
    37441 taaattaata ttaaaagtat agtttttatg gtaaaatgaa taatagtaca ataaagaacg
    37501 aggagagatg taaaatatga gctttatgga taatttattc aacatggcag ataaaaaaga
    37561 attaaaaaag ttcaataaaa ctgttgatat aatagattca ttagaaccta aatttgaatc
    37621 tatggcagac tcggaactta aaaatatgac aaatatattt aaagaaagat tagcaaatgg
    37681 tgaaagtata gatgatatac ttccagaagc ttttgcagta gttagagaag tttctaagag
    37741 agtgttagga cttagacact acagagttca aatgattgga ggtatagtac tacatcaagg
    37801 aagaatagca gaaatgaaaa caggtgaagg taaaactttg gttgcaactg ctcctgttta
    37861 tttgaatgcg cttactggaa aaggtgtaca tgttgtaaca gtaaatgatt accttgcaaa
    37921 acgtgataga gaccaaatgg caaaaatcta tgagttttta ggaatgagtg taggcgttat
    37981 tatacatggt caaaatccaa aagttagaaa agaacaatat gattgtgata taacttatgg
    38041 tacaaataat gaatatggat ttgactatct aaaggacaat atggtaatac acaaagagca
    38101 aagagttcaa agaggattaa attatgctat agtggatgag gttgactcta tactaataga
    38161 tgaggctaga acaccactta tcatatctgg acctggagac aaatcaactc acttatattc
    38221 agatgcaaac acatttgttt taaccttaaa accagatgat tatgaattag aagaaaaaga
    38281 taaggctgta tctctaacag catcgggtat acaaaaagca gaagtgtatt ttaatgttga
    38341 taatataaca gatatatctc atacagaatt ataccatcat ataaatcaag ctttaagagc
    38401 acatgtaata atgaagaaag atgttgatta tgttgctaaa gatggagaaa tagtaatagt
    38461 agatgagttc acaggtagac ttatgtttgg tagaagatat tcagaaggtt tacatcaagc
    38521 aatagaggct aaagaaggtc ttaaaataca aagagaatct aaaacactag ctactgtaac
    38581 attccaaaat tactttagaa tgtacaaaaa actttctggt atgactggta cagcaaaaac
    38641 agaagaagaa gagtttaaag caatctacaa aatggatgtt ttccaagtac ctactaataa
    38701 gcttatgata agggaagact taccagattg tgtatacaaa agtgaaatag gtaaatttaa
    38761 tgctgtagca caagaaataa ttgaaaggca caaagtcaat caaccaatac ttgtaggtac
    38821 agtatcaata gaaaaatcag aattattatc acaaatacta aagaaaaagg gcataaagca
    38881 cgaggtatta aatgctaagc atcatgataa agaggcagaa ataatagcac aagctggtag
    38941 acttggagct gttacaatag ctactaatat ggctggtcgt ggtacagata tagttctagg
    39001 tggaaatcca gactttttaa ctaagagaga aatgagaaga aatggattta aagaagaaat
    39061 agtaaataga gtagatactc caatagaagg tatacctgta aaaggtaatg aaattctatt
    39121 tgaagctaga gaagagtatg aaaaactatt tgaaaagttt aagcaacaaa cacaagaaga
    39181 acaaaaacaa gttgtagaag caggtggact tgctataatc ggtacagaaa gacacgaatc
    39241 tcgaagaata gataaccagt tgagaggtcg tgctggacgt caaggtgacc cagggagttc
    39301 aagattctat ataggtcttg atgatgacct tatgagattg tttggtagtg atagaatatc
    39361 tggtattgta gataaaatag gtcttgaaga agacatgccg atagaacata gaatattatc
    39421 taagtctatt gaaggagcac aaaagaaagt cgaaggtaaa aactttggaa taagaaagca
    39481 tgtacttcaa tatgatgatg ttatgaataa acaaagagaa ataatatatg cagagagaaa
    39541 acgtgtatta gaaggtgaag atttacaaga acaaatacaa tcaatgactc attctataat
    39601 agaagaagca gttactcttt atacacaaga taaaggattt gatgaagaag gattcaaaga
    39661 acatatgtat aatctgttct tgccaaaagg tagcatagaa ataccagaaa tagaaaaact
    39721 taatccagtt gaaataacag aaaaagttta tgaaatagct atgaagatat atacttcaaa
    39781 agaagaacaa gttggctatg agagaatgag agaagttgag agagtaatct tacttcaagc
    39841 tgttgataac cattggatag accatataga tgctatggac caattacgcc aaggtattgg
    39901 tcttcgtgct gtaggtcagc aagacccagt tattgcttat aaaatggaag gttttgatat
    39961 gtttgatgaa atgaataaac atatcaaaga agatactgta agatatttat ttaatataac
    40021 aatagaaact ccagtggaaa gaaaagcagt tgtagatgtt gaaaatctat cttctccatc
    40081 agatggaaca cttccaacaa gtaaaactgt taaaaaagat gaaaaggttg gaagaaatga
    40141 cttatgccct tgtggaagtg gtaaaaaata taaaaactgt tgtggaagat aatctcggag
    40201 gattaaatgt taaagttaca agagtataga catagtatgg agcagatggc ttcaaattta
    40261 gaagaattga gggtttctct ttgacatagc ttcattgatg aaaaatatac aaattaatga
    40321 agaaaagatg aatcaacaag acttttggaa tgataatgaa gtcgctcaaa gagtacttca
    40381 agaaaataaa tctttaaaag agacattaga agaatatgaa agcttaaaaa gcttattaga
    40441 agatatagaa gtattaattg aaataggttt agaagaagat gatgattctg tagaaagaga
    40501 tatagaaaag tccatagaat caatggaaga aaaattatct gaaatgaaaa taaagactct
    40561 tctaaatgga gagtatgata aaaataatgc tatattatct ataaatgctg gtactggtgg
    40621 cttagatgct caagattggg ctcaaatgct tttgagaatg tatataagat ggtcagaaag
    40681 taagggttat aaagttaagc ttttagatat aatatcagac cctgaagcag ggataaagac
    40741 agctacaatt cttgtagaag gaacaaatgc ttatgggtat ttaaagagtg aaaaaggagt
    40801 tcatagatta gtgagaatat ctccatttga cccatcagga aaaagacata cttcatttgc
    40861 atctatagat gtaacaccag agttagatga aaatatagaa gtagaaatta atccatcaga
    40921 tttaaagata gacacatata gagcttctgg agctggaggg caacatgtaa atacgactga
    40981 ttcagcagtt agaataacac atatccctac tggtgtagta gttcagtgcc aaaatgaaag
    41041 gtctcagcat ctaaataagg acagagctat gagactttta atggcgaaat tgatagaatt
    41101 aaaagagtta gagcaaaagg aaaaaataga agatatacaa ggcaaatact cacaaataac
    41161 ttggggtagt caaattaggt catatgtttt tcaaccatat aaattggtta aagaccatag
    41221 aacaaatgct gagtttggta atgtagatag tgtaatgaat ggaaatatag acttgtttat
    41281 taatgaatac ttaaaaatga ataaaatagt ttaataaata tgcactgtaa ttaagatata
    41341 tgtataagaa ggttagtgct taatatgcac ttacagcact taggctgagg acgataaccc
    41401 tcagccttcg ttctgttttg ttatacttat gaaaaactaa cattaggagt gaataaattg
    41461 gatataaatc aaatcttaaa aaaagagttt aatcttagag atgaacaaat aaataataca
    41521 ttaaaactta ttgatgaagg aaatacaata ccatttatag ctagatatag aaaagaaatg
    41581 actggcgaaa tgagtgatgt tacactaaga gaattttatg aaaaattaat gtatttgaga
    41641 aatcttcaaa gtagaaaaga tgatgtagtt agactaatag atgaacaagg gaaattaaca
    41701 gatgaaataa cacaaaatat agaaaaagca aaaacattac aagaagtaga agatatatat
    41761 gctccatata aacaaaagaa aagaactaga gcaacaatag caaaagaaaa aggattagaa
    41821 aatttagcat tgtcaatact agagaataat ttagataata tagaaataga ggcaaagaat
    41881 tatcttgatg aagagaaaga agttctttct attgaagatg ctctaaaagg tgctagagat
    41941 ataattgcag aactagtctc agatgatgct aagattagaa agtatataag agaattagct
    42001 ttaagagaag gtatgatagt tagcaaaagt gctactgatg agaaatcggt ttatgatatg
    42061 tattatgatt atagcgaagc agtaaaaagt atggctccac atagagtttt ggcaataaac
    42121 agaggagaaa aagaaagctt cctaaaggtt aagttggaaa taaataatga taaagtttta
    42181 aattacataa taaacgaata tgtaaatgat aaaaatttca aaaataaaga agaaatcgta
    42241 agttcaatag aagattctta taaaagatta attttcccat caatagaaag agaaataaga
    42301 aatcatttaa cagaaatagc tcaagaaaga gctataagtg tatttggaaa gaatgttaaa
    42361 agtttattgc ttcaaccacc agttaaagac aaagtagtta tgggatttga ccctgcattt
    42421 agaactggat gtaaaatagc tgtagtagat aaaaatggta aactactaga ttatacaaca
    42481 gtatatccaa cagaccctca aaatgatgta gagggagcaa agaaagtttt aaaaggattg
    42541 attgaaaaat acgatataga tataatttca attggaaatg gtactgcatc tagagaatca
    42601 gaaacttttg tatcagaaat gataaaagaa atagatagcg aagtgcagta tgtgatagtt
    42661 agtgaagcag gagcatctgt ttattcagca tctgaacttg caaatgagga acatccagat
    42721 ataaatgtat caataagagg agctatatct atagctagaa gattacaaga cccattagca
    42781 gagcttgtaa aaatagaccc taaaagtatt ggtgttggtc aatatcagca tgatttaaac
    42841 aaaaagagat tagaagaagt actagatgga gttgttgaag attctgtaaa tagtgttgga
    42901 gtagatttaa atactgcatc atactcccta ctagaacatg ttgcaggaat aagtaaagct
    42961 atagcaaaaa atataatagc atatagagaa gaaaatggag attttacgtc aagagcacaa
    43021 ttgaaaaaag taaaaagact aggacctcaa gcatttactc aatgtgctgg atttatgaga
    43081 atcttagagg gtaaaaatcc actagataat acaggtgtgc atcctgaaag ttatgatata
    43141 tgtaaaaaaa tgattgagat aattggatat tctttagatg atgtaaagaa taagaatata
    43201 ggtgaaatag atgaaaaaat aaaagaaatt ggcttgaggg aattaagtga aaaactggaa
    43261 gtaggacaag ttacattaaa agatattata gctgaaatca aaaaaccagg aagagaccca
    43321 agagaagaag gtataaaacc tatacttaga actgatgtct taaaaattga agatatacaa
    43381 gagggtatga ctttaaaagg tacaataaga aatgttgtag actttggtgc atttgtagat
    43441 attggaataa aaaatgacgg attagttcat aaatcagaaa tgagtaatag ttttgtgaaa
    43501 gaccctatga gtattgttac agtaggtgat atagtagatg taaaagtcat tggaattgac
    43561 ttaaacaaaa aaagagttgc cttatcaatg aaaaaataga taagtttatg tatggttata
    43621 gtacttagat tctatatttg taaatgagat tactcgagtg tataaatgtt aaaaatttgt
    43681 aaaagtatat agtaagaaaa tatattaaaa taagaacgat agtcttgaaa atcaggagga
    43741 aaatgaatga tttttataaa aaatggtaaa ataaatacca taacaaatgg gataattcat
    43801 ggagatatac ttatagatga aggaaaaata atagaaattg gagaagattt gatagctcct
    43861 ttagatgtag aggtaataga tgctagtaat aaacttgtgt ttcctggatt tatagatgct
    43921 catactcact taggcttatg ggaagatggt atagggtttg aaggagcaga tggaaatgaa
    43981 gagactgacc caataacacc acaattaaat cctatagatg gaattaatcc aatggataga
    44041 acttttaaag aagcttttga aggtggaata acttctgttt gtacaacccc tggaagtgca
    44101 aatgttatgg gtggtcaatg tatagctata aagacatgtg gaaaaagaat tgataaaatg
    44161 gtaataaaaa atccagttgc atctaaaatt gcttttggag aaaatccaaa gagctgttat
    44221 ggtcaggatg ataaatctcc tcaaactaga atggctatag ctgctttact tagagaaaac
    44281 ctaaaaaaag cagaagaata tttagaggat attgatatgt atgagagtca tgatgatgaa
    44341 gactgtgaaa aacctgaata tgatataaaa atggaaagtt taataccagt tttaagaaga
    44401 gaaattcctt ttaaggcaca tgctcataga gcagatgata tgtttacagc aataagaatt
    44461 gcaaaagaat ttaatttaaa gcttacatta gaccattgta cagaaggtca tcttattgta
    44521 gatgaattag tggaagaaga gtttcctgta atagtagggc catctttgtc agaaaggtct
    44581 aaatttgagc ttagaaattt gacatttaat acagcaggaa tactttcaaa tgcaggtctt
    44641 gatgtatgta taatgacaga ccatccagta ataccagttc aatatcttcc aatatgtgca
    44701 ggtattgcag taaaacatgg tatgaaagaa gaaaaagcaa tagaatcaat tacgataaat
    44761 ccagctaagg ctttaggaat agaagataga gtaggctcta tagaagttgg taaagatgca
    44821 gacctagtaa tttgggataa ttctccacta gagattcaaa gtaatgtact ttacactata
    44881 ataaatggca aagtagtgta tgagaaaaaa taacttgaca attattaaaa aattaactaa
    44941 tataagagtg taaggaaaat taaaaaatca aagaagatct tcggggcagg gtgaaattcc
    45001 ctaccggcgg tatagcccgc gaactactta ggtggttgat ttggtgagat tccaaagccg
    45061 acagtaaagt ctggatgaga gaagatattt atggaagata aataagttta ttttagtttg
    45121 tttaaactat atccataaaa actcgaagat agggtcttcg agttttttgt ttttcctaaa
    45181 aaatataaac atattgatta gggggaaaat aattatgcaa aacacagcaa aaagaggcaa
    45241 tatgatttca acaagaactt tagtagtaat gtcaatttta tctgcaatat cttatttatt
    45301 aatgtttatt caagcaccaa taccaggtat atttccagat ttcttaaaaa ttgacttatc
    45361 agatattcca gcaatattcg gaggaatgtc tctaggacca ttagttggat ttggaatagt
    45421 tgtagtaaaa aatgtgttac aagcaataac agcaacaaca actggaggaa taggagaatt
    45481 tgcaaatata ttaattggtg gttcttatgt aatgatactt tgttattcat ataagagaag
    45541 tggagattta aaaggtgtac tgattggttt tgtattagga acaatatcta tgactataat
    45601 tggttcatta gtaaattatt ttgtaatgtt gccactttat ggtcaactta tgggactaga
    45661 tgctataata ggtttaggtt cagctataaa tcctcaagtt catgatttat tcacttttgt
    45721 aatttggatg atagctccat ttaatgtgct gaaggctgtt ataatatctt tagtaacatt
    45781 gccactttat aaaaaaatgg gaaatataat aaagaaataa ttagacaaga aaatataaaa
    45841 ttaaatgtat tgaatagcca taatttattt ataacttcag tcctatattg tgattgatat
    45901 attaaatata ttatggcttt attaatttat caaaaaatgt atataaaata agaaatattt
    45961 agacaaattt aaattttaaa ataaaggaag aattaaaacg attaactatt aaaatatgaa
    46021 aaaggtatct acaatataca gagcgaattt ataataaaca aaaaataaag ttattattaa
    46081 aaaactataa agattaataa tcaaactttt aataataact aatttaataa tgataggggt
    46141 gtatattcat gcatttatct aaaaaaataa aaaaattatt tttagatgat aaagggtatt
    46201 attttaatag taattggaaa gatattcata ttggtattta tgatacaaaa ttaggagatt
    46261 ctttaaagta tatcactaat gaatatattg aaaatatgga aagggtaaaa tacgattatc
    46321 gtgaattaaa aaatatagaa aatcaaactg atggtatgtg tattttagca ataaggcaga
    46381 attacaaggc attagagtat gtaaaaaatc aaaccgaaga attatgttta gaagcaataa
    46441 agtataatta taaagcactt gaatatgtaa aagaacaaac agaatacttg tgtcttgaag
    46501 ctataaaaaa agattgtaat gcacttaagt atgtacgaaa taaaacagaa gggcttatta
    46561 taaaagcaat aagtcattct tccaatatag atgttgtaag tatactaaag gctttagaga
    46621 ctcaaacaag aaggatatgt ttagaagcaa ttaaaaaaga tggcaggtgt cttgcatacg
    46681 ttagagaaca gagtgaagaa ttatgtatag aggccattaa gcaaaattat aaagcattaa
    46741 aatatgtaaa aaatcaaacg gaaaaaatgt gtatagaatc cgtaagacaa aatggtatgg
    46801 cattacaata tgtaaataaa caaactgata aaatatgtat agaagctgtc aaacaagatg
    46861 gaagaagtat acaatttgtc aacaataaga cagaagaaat atgtataaat gctataagat
    46921 atttaaataa aaaatataat attaaagatg tactaagtta catagataag tatacagaag
    46981 atatatgtat agagattgta agacaaaatg gaaaaatgct tatgtatata aaaaatcaaa
    47041 cagaaaaaat gtgtattgaa gcagtaaaag agaactataa gtctcttaag tatgtaaaag
    47101 agcaatctga gagaatatgt aaagaagcat tgaagcaaaa ccataaagca aaagagtatg
    47161 taaaaattgc tattgatgat tgtatataag gtgtagatac agccatcaat agtgaaagat
    47221 aaaaaaagat aaagacaagt actttataat aatctaggct tatactataa ttaattaagc
    47281 agtgatataa attcacatga cgattatatc aaaatggaga tgaattgatg gcaaaaatat
    47341 atttagaaaa tgaaaataaa actagagaaa taggatataa attaggtaaa cttttaaaag
    47401 aaggcagtgt tatctgttta gtaggagatt taggagctgg taaaactaca atgacacaaa
    47461 gtttggcaga ttcattaggg atagaagatt atataacaag tcctactttt actataataa
    47521 atgaatatga aggaaaaata cctttgtatc attttgatgt ttatagaata ggtagtagtg
    47581 atgaaatgta tgatattggt tatgatgaat atgtaaattc aaatggaatc tgtataatag
    47641 aatgggctaa tctaatagaa gatatacttc caaaagaata tttgaatata gaattgagat
    47701 ataaagatga aggaagagaa atgatattaa ctccaaaagg agagttttat aaagagatag
    47761 ttgaggagtt gattaaataa tgaaaatact aggtatggat acgtcttcta tggcagcaag
    47821 tgtagcagtt gttgaagatg ataacttaat atgtgagttt acagtaaaca acaaaaaaac
    47881 tcattcacaa aagcttatgc caatgataga aaatatgttg agtatgagtg atttaagtat
    47941 aaaagatatg gatttattag ctgtatgtat aggtccaggt tcgtttacag gacttagaat
    48001 aggtatggct acagtaaaag ctatggccca tgtaaataat ataccaataa tagcagtaaa
    48061 ttctttggaa tctctagcaa ataacataaa tttctgtgat agaaagatat gttgtatatt
    48121 agatgcacag aaaaatcaag tttattcagc taaatacaag tttgaaaatg gagagatgat
    48181 agaattagat ggtgttgatg ttgtagagtt tgatgcttta gtagatgaaa ttgtatcaac
    48241 taatgaagaa tttataatag ttggagaagc tgtatacaaa tataaagaca agttagagaa
    48301 tataaaaaat ataaaaatac cttcaccagc taataatgta tctaacgcag gaagcttatg
    48361 ctctttagca ttaaataaat ataataaaaa tatagatgta catacttgtt atacgataaa
    48421 tcctatgtat atcagaaaat ctcaagctga agtacaatat gatgaaaaaa tgaagaggct
    48481 aaataatgga agataataca aaactaatag tagatgatat aaaaatagaa gaaatgacta
    48541 cagaagatat agatgaagtt tttgaagtag aaaaaaattg ttttgaagat tattggtcaa
    48601 aagagtcttt tagaaaagag ttgtctaatg aagtagcaag gtatatagta gctaagttaa
    48661 atggaaaaat tgtcggatat gtgggaattt ggcttatact tgatgaaggg catataaata
    48721 atgtggctgt tcatagtgac tatagaggga aaaaaatagg ggacaagttg ataaaaggca
    48781 tagttgattt atgtaaagat aataatattg catctatgac attagaagtt agagcatcaa
    48841 ataaaatagc acaaaattta tatagaaaat atggatttaa aatgggtgga ataagaaaag
    48901 aatactacag tgataataaa gaagatgcaa ttataatgtg gaaccaatta aaagaggtgt
    48961 agagtttatg agtgatataa taacattagc tatagagagt agttgtgacg aaacagctgc
    49021 atcagtttta aaaaatggta gagaaatact ttcaaacata atctctactc aaatcgagac
    49081 acataaaaaa tttggtggtg tagttccaga agtggcctca agaaaacatg tggaaaatat
    49141 tgatatagtt gttcaagaag ctttagacaa agcaaatata ggttttaatg atatagacca
    49201 tatcgcagtt acatatggac ctgggctagt aggtgcttta ttggttggtc tatcttatgc
    49261 taaagcactt gcatatactt tgaatattcc acttgtagga gtaaatcata tagaagggca
    49321 tctaagtgca aactatatag agcataagga tttaaaacct ccttttataa cattaatagt
    49381 atctggaggt catactcact tggttgaagt aaaagattat ggcaagtatg aaattttagg
    49441 aaaaacaaga gatgatgcat ctggagaagc atttgataag atttcaagag ctatgaattt
    49501 aggctatcca ggaggtccta ttattgataa tctggccaag aatggaaata aacatgctat
    49561 agaatttcca agagcctatt tagaagaaga tagctatgat tttagtttta gtggattaaa
    49621 atcttctgta ttaaattatc taaatggaaa aagaatgaaa aatgaagaaa tagtagttga
    49681 agatgtagca gcatctttcc aagaggctgt agtagaggtt ttatctacta aagcactaaa
    49741 agcagtaaaa gacaaaggat acaatatcat aactctttct ggtggggttg cttctaattc
    49801 ggggcttaga gctaaaataa cagagcttgc taaagacaat ggtattactg ttaagtatcc
    49861 tcctctaatt ttatgcacag ataatgcagc tatgataggg tgtgcaggat attataattt
    49921 tataaatggg aaaacgcatg atatgagttt aaatgcagtt ccaaatttaa agataaatca
    49981 gtagagttag atgaatttgt aaatataaaa gtattgtttc aaaaaagtaa gtagaagtga
    50041 aattaaatat aataaaaata aatatagtat atattaaaac ttgaagtaaa actatttata
    50101 atctttatat tccaatgaat tgcaacaaat tttaggatat acagattgtc tttggcttag
    50161 atttgcttca agtttatttt tttctataga aagattattt taaaaagtgg gtaatatacc
    50221 cttttttttc attcttaaaa agttttatac taattataga aagattaagg aggggaagaa
    50281 atgagtcaaa gtaaagaaga caaaataaga agtattttgg aagcaaaaaa tattaaatca
    50341 aattttcaaa ataaagaaaa tttaagtgaa tttaatgaaa aaaaagcaag taaaagagca
    50401 gaagacttat tagatgtata ttataataca ttatctactg ctgatatgga atttccatat
    50461 tggtataata gagaatatag aaaatcagat ggtgatatac cagtagttag aagagctaaa
    50521 gctcttaaag ctgctttttc acatatgaca ccaaatataa tacctggtga gaaaatagta
    50581 atgcaaaaga cacgccatta tagaggttct tttccaatgc catgggtaag tgaaagcttc
    50641 tttgttgctc aaggagaaca aatgagagaa gaggcaaaga aattagccag taacacagct
    50701 gatgaactta caaaatttgg gtctggtgga ggaaatgtta ctgaaagttt tggaaatgtc
    50761 gtttcaatag ctggtaaatt cggaatgaga aaagaagaag tacctgtact tgtaaaaatg
    50821 gcaaaggaat gggttggaaa gtctgttgaa gatttaggtt ttcactatga aaaaatgatg
    50881 ccagattatg atttaaaaga aaacctaatg agtacactta tatgcatgtt tgattcaggg
    50941 tatacacttc ctcaaggtag agaagttata aattattttt atcctttaaa ttatggatta
    51001 gatggaatta tagaaatggc aaaagaatgt aaaaaggcag ttgcaggaaa tgcatctgga
    51061 gatgggctta ttggtatgga ccgtctatat ttttatgagg ctgttattca agttattgaa
    51121 ggattacaaa cttggatttt aaattatgca aaacatgcaa aatatttaga aagtatagag
    51181 acagatttag aagctaaaaa agaatactca gatttagtgg agatattaga acatattgca
    51241 cataaacaac ctcgtacatt tagggaagct cttcagttga cttatacaat tcatatagca
    51301 tcagtaaatg aggatgctat atctggtatg tctataggac gttttggtca aattttatat
    51361 ccttggtatg aacaagatat agaaaaagga ctaattacaa aagaagaggt tatcgaatta
    51421 ttagagcttt atagaataaa aatcacttgt attgactgtt ttgcttcagc gggcgtaaat
    51481 ggaggagtac tatcaggcaa tacatttaat actttatcta taggtggatt aaaagaagat
    51541 ggttctacag gagctaatga actagaagag ttattattag aagcaagtat gagatgtaga
    51601 actcctcaac ctagtttaac tatgctatat gatgaaaagc ttccagaaga tttcttaatg
    51661 aaagctgctg aatgtacaaa gcttggttct ggttatccag catgggtaaa caactcaaat
    51721 ggaacaacat ttatgatgaa acaatttgct gatgaaggta tgactgttga agaagcaaga
    51781 gcatttgcat taggtggatg tttggaaacg tctccagggt gttggaaaca gttaacttta
    51841 aacggaaaaa catactctat tgcaggtgga gcaggtcaat ctgctggctc tggagttcac
    51901 tttatagcta atccaaaaat tttagaactt gttcttatga atggtaaaga ctatcgtatg
    51961 aatatacaag tatttgagcc tcataataag ccattagata cttatgaaga agtcatagaa
    52021 gtatttaaag attattataa acaagcaata aatgttttag aaagagcaaa taacattgag
    52081 ttagatatat ggagaaaatt tgatacttct ataataaatt cactactaaa gccagactgt
    52141 ttagacaaag gtcaacatat aggaaatatg ggatatcgtt ataatgcaac attaaacgta
    52201 gaaacttgtg gtactgttac tatggtcaat tcatttgcag cacttaagaa acttgtatat
    52261 gatgacaaag catttacaat agaggaaatg aaggatgcca tattaaataa ttttggattt
    52321 aaagatgcat tagaagtagg aaattattct atggcagacc aagtaaaagt agataagact
    52381 ggtaaatatg atgctattta taaggcctgt cttgatgcac ctaaatatgg aaataatgat
    52441 ttgtatgcag ataatattct taaaaactat gaggtatggt tatcaaaagt atgtgaagaa
    52501 gcacaatctt tatatgctaa gaagatgtac ccttgccaaa tatctgtttc tacacatggg
    52561 ccacagggag ctgctacctt ggctactcca gatggtagac taagtggaac aacatattca
    52621 gatggttcag tctctgcata tgcaggaaca gataaaaatg gagtatatgc attatttgaa
    52681 tctgcaacta tttgggacca agcagtagtt caaaattctc agatgaattt aaaacttcat
    52741 ccaactacta taaaaggaca acaaggaact aaaaaattat tagatttaac aagaagttat
    52801 ttaagaaaag gtgggttcca tattcaatat aatgttgtag attcagaaac attaaaagat
    52861 gcacaaaaaa atcctgacaa ttatcgtcaa ttaatggtac gtgttgctgg gtttactcaa
    52921 tattggtgtg aattaggtaa accaatacaa gatgaagtaa ttgctagaac agagtatgaa
    52981 ggggtgtaaa atatgagaaa gcatagtgat tgtatgaatt tttgtgcagt agatgcaacc
    53041 aaaggaattt gtagattatc aaaacaaatg attaatttag atgatgcagc atgtccagag
    53101 ataaaagtaa tgccaaaatg taaaaattgt aaaaattttg ttgaagctaa tgatgaaggt
    53161 ataggcaaat gtgttggcct agagaaagaa gactgggtat attcaacatt gaatgcaatt
    53221 acttgtgaag gacatgtgtt taatgagtag tcaaaagcaa ttagaaggca tgatttttga
    53281 tgtacaaagc ttttcagttc atgatggtcc aggttgtaga acaactgtat ttttaaatgg
    53341 atgtccactg agttgtaaat ggtgtgcaaa tccagaaagt tggactgtaa gaccacatat
    53401 gatgtttagt gaattatctt gtcaatatga aaatggatgt actgtatgtc atggtaagtg
    53461 taaaaatggt gcattgagct ttaatcttga taataagcca gttatagatt ggaacatctg
    53521 taaggactgt gaaagttttg aatgcgtcaa ctcatgttat tataatgcgt ttaaattatg
    53581 tgcaaaacct tacactgtag atgaacttgt gcaggtaatt aaacgtgatt ctaacaattg
    53641 gagaagtaat ggaggagtaa catttagtgg aggtgagcca ctacttcagc atgaattttt
    53701 acatgaagta ttattaaagt gtcatgaggt aaatatacac actgccattg aaacgagtgc
    53761 atgtgtatca aatgaagttt ttaataaaat atttaacgat attgattttg catttattga
    53821 tataaagcat atggatagag aaaaacacaa agaacaaaca ggtgtgtata atgatttaat
    53881 attagaaaat atatcaaacc ttgcaaattc tgattggaat ggaagattag tacttagagt
    53941 accagttatc tctgggttta atgatagtgt tgaaaatata agtgatatta tatcttttat
    54001 gcacaaaaat aatttggtag aaattaatct attaccattt cacagattag gagaatcaaa
    54061 atggattcaa ttaggcaagg aatatgagta ttctgataag ggtgatgttg atgaaggtca
    54121 tcttgaagaa ttacaagata tatttttgga taatggtata gcttgttatg ttggtcatga
    54181 gacagctttc taaaattaaa tacaagtttt aattaaaaaa aggatgttac actaaaagct
    54241 agagttacat ccttttttat gtggttttta tgtagaaata attaagtaaa gttttatatg
    54301 ttttatatat tgtttatatt gctttatgtc cataaatatt gctttaaata tactttatat
    54361 attttttata gtttaaatta cagttagaga atatattacg cttacttcat tgaagcagaa
    54421 gttttgtggt aaaatactac tatgaaaaaa tttaatagaa tatattttag aaacaactaa
    54481 aaataatagt taggaggaag acatctatat gaacaaatca tggagcaact tgattattaa
    54541 gaataaagac aaaaaagtac gttcagggtg gattattata gctgttatgg ctacctttta
    54601 catacttcag tattatttaa gcatgatact tgtggaaata ataagaaaaa tcctggttgc
    54661 tacaggtgac attaatttaa aaacaaacta tttttcagaa tatgctaatt ggttaaatga
    54721 tgttgggtta cagattgtat ttcaaattct aacagattca cttatgatta ttattcctat
    54781 aattgtatgg agatttatta tgaaaaatcc tattagtgaa atgggattac attcttatag
    54841 aattaagaaa aaagaaggat atgtaggaat gttattagga atatttaatt gtacagtaat
    54901 ctttattata acaataacaa ttggtggtgg tcatgttact tcatgggtac caaaaatttc
    54961 acctttaaca gtttcttgga tacttgtctt tattttagtt gcttttgcag aagaaatttt
    55021 aaatcgtggt ttttttatgg cagttttacg aagatgtaaa aatatttatt ttataatgat
    55081 tgttccatct gttatttttg ggttgattca tatatggaat cctgatgtta cttttttatc
    55141 tgtaattaat attataatta ttgggattct tttttcatat atgtttataa aatcgtcgaa
    55201 tatatggatg tgtataggtt atcattttac atggaatgta tttcagggga ttatatatgg
    55261 tatgcctgta agtggacttc aggttccagg gattataact acacaaatca ctcatggtaa
    55321 tctattaaat ggaggaatgt ttggtattga aggtggaatt ttgactactt ttgttaatct
    55381 acttagcttt atatttgtat ggtattacta tagagattct aagtatgatt ttgttagtaa
    55441 taagtaagtg tgaataatgt taagaactaa ttaattataa taaattttaa taatatattc
    55501 taggcttaaa gtattctgta ggattgttgg aaatttacaa aaatataaaa ataacttgga
    55561 cattctattt actccaagtt atttttatat tcttttgtaa atagaaatgg aacataaaaa
    55621 attaaaacaa ccatagatac tattagtata tcatggtaag tgatagttga ttctttagaa
    55681 tttgtgataa gaaaagcact attatttaaa acatgaatta tagcacaacc agatattctt
    55741 agtttttata taaagatatc ctaaaaatat tgaaattcca actatatgta ttgaacgtaa
    55801 tattattcct aatattggcg cttcaggtgt atataatgta aatattagtg gtaagtgcca
    55861 caagctccaa cacataccta atattataac tcctaacttt ttaccaaatt tatcaaaaaa
    55921 aatattctgt aaaaaacctc tccaggcata ttcttcacta aaaaaaatat aaatagtagt
    55981 taatgatgtt attggagtaa atataaattt tatgatacca ctataattag gttgagcccc
    56041 ttgtagtatt agtataaatg atgttggaac aattacagaa atcataaagt aaataattaa
    56101 taaagaacct agtttaatat tttttacagg atataaattt tttttatttg atgaatatat
    56161 tataattgat aagctactta taaaagttaa tattaggttt ataattataa attcattatt
    56221 atttattaga tttaataact taagaacaat taataatgaa taaataagaa aaaataatat
    56281 gattagtgaa taaaattcat acatatcatt atttaatcct tcagtataaa actttgcaat
    56341 agcaactgaa gatagaggta atatcatcat gaatgatgca aagttttctg gatcaataaa
    56401 tttattataa tataacagta aacctaatga ataagttaaa ccaaagttta taaagaaaaa
    56461 gataataatt tgtatttttt ttctttttat ttcattttta ataaatactg ggtttagaat
    56521 atttat
//
LOCUS       DAFAZV010000025        56241 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFAZV010000025 DAFAZV010000000
VERSION     DAFAZV010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 56241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56241
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.025"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            248..2437
                     /locus_tag="KOU88_002156"
     CDS             248..2437
                     /locus_tag="KOU88_002156"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin-dependent
                     ribonucleoside-diphosphate reductase"
                     /protein_id="HBK3212033.1"
                     /translation="MKYIIKRDGTKELFSKSKIEDAVYKASINSEGGVDRELAYDISR
                     KIANDYNSMEKCLSVEEIQDIVEVLLMESNRKDIAKHYILYRERRSEIRTKAWEFDEL
                     QKSIWKNKYRHNGESFDEWIKRISNNSSRISKLIRQKRFLFAGRILANRGLQKEGKKV
                     TYSNCYVIEPPKDSIEDIFDTAKKLARTFSYGGGVGIDISKLRPKGAKVNNAAKHTTG
                     AVSFMELYSMTTGLIGQRGRRGALMISMDVNHPEIEDFIDIKTDLEKVTKANISVRVT
                     DEFMQAVREKKLYNCTFEVETTGEKIVKIVNAYDLFNKFVKNNWDYAEPGILFWDKIK
                     TYNFMSEDKNFCFSGVNPCAEEPLPSGGSCLLGSINLSEFIIQPFGEHATFDINKLKS
                     CVREAVVALNDVLDEGLNLHPLQEQRDSVHKYRQIGLGVMGIADMLIKMGIRYGSDES
                     LELCDLIGKTMLNEAVKQSALIAKEYGTFSEYKYENISKSKFFIENLNEDTKEMVKKY
                     GLRNSQLLTIPPTGSISTMIGISGGIEPIFNLSYIRKTESLHDEDVYYKVYTPIVKEY
                     MDKKGITDEECLPDFFVTAMNIGYEERINMQKVWQKYIDASISSTINIPFETTVEDVF
                     NIYIKAWEAGLKGVTIFRDGCKRSGILINEKKEENNKEDKKENSKKEYYKNNKKEKDN
                     KDEKAKEIINKNFEEDEKFVCPECGSEGIAHTGGCSICLKCGYSGCN"
     gene            2505..3272
                     /locus_tag="KOU88_002157"
     CDS             2505..3272
                     /locus_tag="KOU88_002157"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBK3212034.1"
                     /translation="MQDKSVREIKEIIETLEVEKYMEYIELLRVDERKSVQGLAIKLA
                     KKLDNIRKEEERLETINIFENEGYDKGYLYIGGIDEAGRGPLAGPVVASVVVFKKDTK
                     IEGVNDSKKLSEAKRDELFEVIKEEALDYGIGIVNNEEIDEFNILNATYMAMKKAINC
                     LKKAPDYLLVDAATIPGIDISQNPIVKGDSKSISIAAASILAKVTRDSIMYQYDRVYP
                     EYGFKSHKGYGTKEHYEAIEKYGITPIHRKSFLKNIL"
     gene            3330..4346
                     /locus_tag="KOU88_002158"
     CDS             3330..4346
                     /locus_tag="KOU88_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBK3212035.1"
                     /translation="MEYNGLLKSARENLNGSCKVCKVCNGVACAGEVPGMGGKGSGSS
                     FIENSKSLEKVKVNMRVIHDVSNPDTSIEMFGKKMSAPIFAAPVTGTTLNMGGKINER
                     DYIEPVVAGCANSGIYAMVGDTAVDAFLMENLDVVKKYNGAGIVFIKPWDNENIIKKI
                     RLAEEAGAFAVGVDIDACGLVTLSLHGKPVLPKNVKQIKELVKSTKLPFILKGIMTVE
                     DALMAVEAGVDAIVVSNHGGRVLDCTPGACEVLPKIADAVKGKVTILADGGVRTGLDV
                     LKMIGLGADAVLIGRPFVTASFGGATDGVETYVNKLQSELSSSMILTGCQTIKDIDGK
                     VIYK"
     gene            4412..4660
                     /locus_tag="KOU88_002159"
     CDS             4412..4660
                     /locus_tag="KOU88_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212036.1"
                     /translation="MSRKAYEEALVELEKFIDERKEIIKSAEDCIDKYIVDRTLPFDY
                     KDKCVEWQQELLDIAEAQVLEANELSVLLQEKKELEED"
     gene            complement(4836..5333)
                     /locus_tag="KOU88_002160"
     CDS             complement(4836..5333)
                     /locus_tag="KOU88_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBK3212037.1"
                     /translation="MYKIGESVMYPKEGACSVNDIVTKKINHEMQKYYELSVIFNSNL
                     KISIPVLNADRIGIRPVMDGNDVDNFIQSINKTDGVWIFDRKERLKLYQDKFHSGDVF
                     EIVKLIKMLMIQDSSKQLCSTDKEFLNKAQKFALSELAAAQCKSYTMVLEEMKKHILN
                     SKNTN"
     gene            complement(5577..6641)
                     /locus_tag="KOU88_002161"
     CDS             complement(5577..6641)
                     /locus_tag="KOU88_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212038.1"
                     /translation="MIRLTIANIKRYLKNHTLLINMVMLPIILIFSLNFFINNSGNQS
                     MYFSPVAIVSDSSGKYEHKLINSSKLKENSFRLNEQDKAMNLLKNNKVSAVFVLDKNF
                     SNSIDKLQRPVVKCFKIENGGGSLWAESQIESFITKSLKLKVDKNIDDKLTKTNIIDN
                     KPDKNKGSFLVVFLICYFMYINAAHLASDLFTLKKSNVLKRLISTDNKDIKIIFSIFL
                     GLFFIQSIVYTFALLCFSIIEDFNLSLNVLMIVLANSFVSTGFVFWVARVFKNESSIS
                     LISTFYSLIGLAISISSLIPSMDKLSFMTNLSKFTPFYWTIDAIKNNGSILINIIALI
                     LIGIIFVTAGSLKLRDFAKN"
     gene            complement(6644..7741)
                     /locus_tag="KOU88_002162"
     CDS             complement(6644..7741)
                     /locus_tag="KOU88_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212039.1"
                     /translation="MKLYMSVKTMLKGLKSSFILNLIYFLALPLILSWFLGMVTESMF
                     QNPIKTESTPIVIYDKDNTRLSNDLTKYLKNDLSYILTVKKDDSKAELKLTIPKGYES
                     SLLNEKSNTLNIEKLGTRDDIAILLQDILDTYHEKFYLNNSQKISSEDFSKLFNKNSI
                     DTSIINNNVKQSSYEYFALVSLGFLVIIFIMNNILSNYISESKGLSKRLYSMPITRVQ
                     FLIYDFVGLWIYSFIFLLLYVLFFRILGITFKGNFAILLLLCALSSYFMTSISTFVTS
                     FFSKKYGTAIVYALLFLQTIFGGIFSMISDTFTKLTSLSPTYLIGELFSNYETFKTID
                     SIGDLIFTCLIISTILIALAIVKEKYKWREV"
     gene            complement(7755..8690)
                     /locus_tag="KOU88_002163"
     CDS             complement(7755..8690)
                     /locus_tag="KOU88_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212040.1"
                     /translation="MDIVRVNNITKRFNDKLVLDNISFSVKKGEIFGLIGPNGAGKST
                     LINIITNLMLPNSGSIQINDLDLSKDYIKAKSIIGLVPQELAIIETLTPFDNLEYFGA
                     FYGLKGKLLKERIIEALEVTGLTEVKKKKVKKLSGGMQRRLNIGIALLNHPKILILDE
                     PTVGVDPQSRNHIFNFIKDISKKHETTVIYTSHYMEEVEHLCSKIFIMDEGKEIAFGD
                     NDYLKSLVSTNTKLIMEIKNINAQLIFDLKNTKGVISVLENNSLLELDIDKKLQLTDI
                     LSIIDKNDSKIMKISYEEPSLEDVFLNLTGKNLRD"
     gene            complement(8819..9466)
                     /locus_tag="KOU88_002164"
     CDS             complement(8819..9466)
                     /locus_tag="KOU88_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3212041.1"
                     /translation="MNKIKVLIVDDEKLIRKGLKIILSSYNDLEIVGDASNGYEALEF
                     CKMNDVDIVLMDIRMKVCDGVLGTRLIKEYNNSITLLILTTFNDDEYIKDAMKFGASG
                     YLLKDSSDEVLHEGIRSSFFGNIVLDKSVAEKIMTSEKTVKQEHLYDMYNLTEKEISI
                     IRLIANGLNNKEISQELFLSEGTIKNNITNILAKLELRDRTQLAIFAFKNKIVIE"
     gene            complement(9459..10622)
                     /locus_tag="KOU88_002165"
     CDS             complement(9459..10622)
                     /locus_tag="KOU88_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK3212042.1"
                     /translation="MNREKLVAFIRYLSLFILVVSYLKNVENTLYPVITMIILFLIII
                     NNQVRFFSLSNENKFILISYFLELILIFILCNYTKTFNSIYFVPLILDISFLIKEKYK
                     YILFSFVIISSLIISLDKNIYLALESSSILLIITVLSIYIENENLSKLYSQNLYDKLR
                     ISKDELKKVNADLETYASSIEELAILKERNRISREIHDSVGHSLSTTIIQLNAIEKLL
                     KDKPLIYDLVHELREFVTESFQDVRRAISELKPVEYENYQSLFKIKELVKSFIKLTNI
                     NVKLTISKNTWNLSRNQSIALYRLIQESLSNSSRHGKATEIRIFITFNTSNLIITISD
                     NGIGCGNIKKGNGLNSINERIYELNGKVEFDNSNNGFTIRASFPKFSGGDFFE"
     gene            10806..11150
                     /locus_tag="KOU88_002166"
     CDS             10806..11150
                     /locus_tag="KOU88_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBK3212043.1"
                     /translation="MNNKEKGDFGEKVAVNYLLSKGAKILEKNYRLKIGEIDIIAKME
                     DEIIFVEVKSRSNIKFGYPCESVSFKKRKKIIGVASYYIIKNNLNNTPIRFDVIEVYL
                     LEKRINHIMNAF"
     gene            11181..12782
                     /locus_tag="KOU88_002167"
     CDS             11181..12782
                     /locus_tag="KOU88_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HBK3212044.1"
                     /translation="MLSIINSSNLVGIDSFLVKVEVDVSNGIPSFNIVGLPGKEIKEA
                     RERVKSAILNSGYKFPSTRIVVNLSPADIKKEGAFLDLSISIGLLRELIKKDENYIRE
                     SMFIGELSLDGKIRKVRGILPIIMGAKTQNIKRIFIPIENIKESLFVDEIDIIPIKSL
                     KECVDFLNEEIKVDKVRIMSFLDDKSRKENEELEKDNSYIDCKYTKINNEESKYDEDF
                     KDVKGNYFVKRSAEIAAAGNHNMFMIGPPGSGKTMIAKRVRTILPDISVEEMIEVSKV
                     YSILGMINETKGIIDKRPFRAPHHTTTKQSLIGGGMDARPGEIALAHRGILFLDEIAE
                     FDRKILETLRQPIEDGYVNISRVKYSAKYPCRVLLVAAMNPCPCGYYMSETECRCRSN
                     EIDRYINKISGPLLDRFDIFVEVNSIKYSDFNSLKQEESSQKIKRRVENARKIQINRF
                     KKDNIKNNSEIKAYNLFKYCKLEKEASKTAEMIFSKYNLSSRSYTKLLKMARTIADLE
                     ERDLINSQCIIEAFSFRKAYYSYFK"
     gene            12801..13901
                     /gene="dprA"
                     /locus_tag="KOU88_002168"
     CDS             12801..13901
                     /gene="dprA"
                     /locus_tag="KOU88_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBK3212045.1"
                     /translation="MEKRDTYLWLKSIGGITTKTIEIIENEIVNIEDIFDFSEKEIYN
                     LKNISLNIRKNIVKYRGHAYLENIKELLYKKAIKYICKYDKEYPENLKNIYNAPKLLF
                     YKGDIGLVNNNFNIAIVGSRKPTAYGINCAKTISCQLSQYGVNIVSGLAIGIDAYSHI
                     GCMSGKSKTIAVLGSGVDNPLPKQNLHLSNKILENGGLLLSEYNINSTVAPYHFSNRN
                     RIISGLSDGVVVVEAAIKSGALITVDFALEHGKNVFAIPGNINSQMSRGCHKIIKEGA
                     KLIENIDDILNEYNIFNIIDKKINQKYDNISLNAKSKQIIEAIKREGNLHIDSICDYT
                     GIEIKYVNSIINELVLNELVVEMNNKTYSLNV"
     gene            13934..16021
                     /gene="topA"
                     /locus_tag="KOU88_002169"
     CDS             13934..16021
                     /gene="topA"
                     /locus_tag="KOU88_002169"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBK3212046.1"
                     /translation="MAKTLVIVESPAKAKTIEKFLGKSHYTVKASVGHVRDLPKSKLG
                     VDIENNFEPQYINIRGKGDVIKELKKEAKKSKQVYLATDPDREGEAISWHLAHILNLD
                     ESEDCRIEFNEITKDAIKKAIKHPRNIDINLVDAQQARRVLDRLLGYQISPILWQKVR
                     KGLSAGRVQSVTTKLICDREKEIKAFIPKEYWTIDVEAKTVKDKDITLKFYGKNDEKI
                     ELENEEAVNEILKEMEGKDLKVEKIESKSRRKSAPKPFTTSMLQQEGANKLFFTTKKT
                     MMIAQELYEGIDIEGEGTVGLISYIRTDSKRISDEAKEKAKGYIVNNLGENYYKNTGD
                     KKEKKDTKKVQDAHEAIRPTSVDRTPESIKASLSKDQYKLYNLIWRRFVASQMEDSVF
                     DILNVECKIGDIVFKATGSKMKFDGYTKVYNFSEREDKILPSIEKGDILNIENILPDQ
                     HFTQPPARYTEASLVKTLEELGIGRPSTYAPTIATILNREYVEKQGTSLCPTELGIIV
                     TDILENNFHKFIDVDFTADMESKLDVIEEGNTDWKKIVSESYAPLKEAIEEALENIEK
                     VNMDEETDEICENCGSNMVIKYGRFGKFMACKNYPDCKTTRPIMNKIGVKCPKCEEGD
                     IILRKSKRGKAFYGCSNYPNCDFVAWNKPTGEFCEKCGSYMVEKVTKSETKTVCSNKE
                     CNKETKEHNDGKE"
     gene            16186..16971
                     /gene="codY"
                     /locus_tag="KOU88_002170"
     CDS             16186..16971
                     /gene="codY"
                     /locus_tag="KOU88_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBK3212047.1"
                     /translation="MASEVLQKTRKINKTLQTSGGSSVSFDLLAGALGDVLSSNVYVV
                     SAKGKVLGLHLNDVQDSSVIEDEYTKQKKFSDEYTQNVLKIDETLENLNGEKILEIFP
                     EEHGRLQKYTTVVPILGSGQRLGTLVLSRYSNSFNDDDLVIAEYSATVVGLEILRAIG
                     EELEEEMRKKAVVQMAIGTLSYSELEAVEHIFAELDGKEGLLVASKIADRVGITRSVI
                     VNALRKFESAGVIESRSLGMKGTHIRILNDKLTDELKKLKNNQ"
     gene            17078..18343
                     /locus_tag="KOU88_002171"
     CDS             17078..18343
                     /locus_tag="KOU88_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBK3212048.1"
                     /translation="MPLADKIRPKTMNDVIGQSHIIGNGKILSKILQSNFLPNMIFFG
                     PPGVGKTTVAEIIAERSNKSFYKINATNSSLEDIKKVISELGSINNVNGVLLYIDEIQ
                     SFNKKQQQSILEFMENGSITLIASTTENPYHYVYKALLSRSTVFEFKPLEKLDVEKGL
                     KRAVEVLNEDSYMDIECNNDAIEDIAILSDGDMRRALNILEVVVYSTKPNKDNITYID
                     SDVIRASTFNKIINYDKNGDSHYDILSAFQKSIRGSDPQASIHYLARLIKGGDLISIC
                     RRLLVIASEDIGLAYPNAIVIVKACVDSAMQLGFPEAKIPLAEATILLATSPKSNSAC
                     IAIMKAMDELDKEFVKDIPNSIKDAHYSGSKEIGRGCGYKYPHNFKNHYVKQQYLPDS
                     IKDSIYYIPQENKTEKNIKKYLEYLNSDF"
     gene            18374..19144
                     /locus_tag="KOU88_002172"
     CDS             18374..19144
                     /locus_tag="KOU88_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3212049.1"
                     /translation="MIIKLNSTYHSRVMKYLKKEPEYNLFIIGDIERYGYGNNFLNIW
                     ADVGEHGEIKAILLKYFEFMMFYSDGEYDVEGFYNLLRNTNYEEISGKICAVDALAKR
                     LGLNNLKVVDFCKLQTKKFLIDNNCNAKVKRIRLGNLKKTVKLYDLIDEFHSTTLENL
                     KNGLRTGRGYCIEINKQVVSMAKSTSENRTHAMIIGVGTHPKYRAKGLATKCLIKLCS
                     ELLRENKIPCLFYDNEEAGKIYKKLGFENIGKWGIYSK"
     gene            19253..19699
                     /locus_tag="KOU88_002173"
     CDS             19253..19699
                     /locus_tag="KOU88_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBK3212050.1"
                     /translation="MKLSTKGRYGLKAMFELALNQDNGPVSLKFIAKKQKISDQYLEQ
                     IFSSLKKSGLVKSVRGAQGGYLLSKNAEDITVGDILVVLEGPVALSDCVLDEDVCENS
                     NMCVTKIVWEKMKKGIEDVIDSITLKDMINDYNKNKLENDITNIKK"
     gene            19717..20910
                     /gene="nifS"
                     /locus_tag="KOU88_002174"
     CDS             19717..20910
                     /gene="nifS"
                     /locus_tag="KOU88_002174"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase NifS"
                     /protein_id="HBK3212051.1"
                     /translation="MEKRRLYMDYSATTPIKKEVLDAMMPYLTDYFGNASSFHTFGRE
                     AKDALDKAREQVAALINAEPSEIYFTAGGSESDNWTLEGIAYANKNKGNHIITSKIEH
                     HAILHTCEYLAKHHGFEITYLDVDSEGKVDLKQLEDSIKDTTILISIMFANNEIGTIQ
                     PIKEISEIAKKHKILFHTDAVQATGNIPVDVKELGIDLMSMSSHKIYGPKGVGALYIR
                     KGVRLHNFVHGGAQEKSKRAGTENIPAIVGYGKAAELAKENMQNHVETLTRLRNKLID
                     GVLERIPYTRVNGSLENRLPGNANFAFQFIEGEGILLLLDMLGIAGSSGSACTSGSLD
                     PSHVLLAIGLPHEIAHGSLRLTVGDFTTDDDIDYILENLPKVIERLRSMSPLYDDAKK
                     QGLVK"
     gene            20964..21404
                     /gene="nifU"
                     /locus_tag="KOU88_002175"
     CDS             20964..21404
                     /gene="nifU"
                     /locus_tag="KOU88_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold protein NifU"
                     /protein_id="HBK3212052.1"
                     /translation="MQYSDKVMEHFMNPRNMGEIDNASGVGEVGNPTCGDIMKIFLDI
                     DGDVIKDVKFKTFGCGSAIASSSMATEMIKGKTIKDALELTNKAVAEALDGLPPVKMH
                     CSVLAEQAVKAALIDYAQKNNIHIPELDGYVIDDAHDHDVEEEE"
     gene            21693..22772
                     /gene="mnmA"
                     /locus_tag="KOU88_002176"
     CDS             21693..22772
                     /gene="mnmA"
                     /locus_tag="KOU88_002176"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBK3212053.1"
                     /translation="MNKKVMIGMSGGVDSSVAAYLLKQQGYDVIGVTMKLWQDDDVVE
                     IEGGCCSLSAVEDARRVANKIGIPFYVLNFREVFKEKVIDYFIDEYLEGKTPNPCIAC
                     NKHIKFDDFYKKARQIGCDYVATGHYAKIEKDESTGRYLLKKSVTDKKDQTYALYNLT
                     QEQLEHTLLPIGDYEKDRVREIAKEMGMAVHNKPDSQEICFVKDNDYANYVKKHSKKR
                     IEEGFFVDTKGNILGKHKGILYYTIGQRKGLGITFGKPMFVIDINPINNTIVLGDNED
                     LFKKELIAKDVNFISIDTLEEPLRVQAKIRYSAKPSPATIHRVGEDTIKIVFDEAQRA
                     ITKGQSVVMYDGDIVVGGGIIEKSL"
     misc_binding    22915..23153
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            23221..25860
                     /gene="alaS"
                     /locus_tag="KOU88_002177"
     CDS             23221..25860
                     /gene="alaS"
                     /locus_tag="KOU88_002177"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBK3212054.1"
                     /translation="MEKMGLNEIRSKFLEFFESKGHYVANSYSLVPNNDKSLLLINSG
                     MAPLKNYFSGVEVPPSVRMCTSQKCIRTGDIENVGITARHATFFEMMGNFSFGDYFKR
                     ESIKWGWEFVTEWLNIPEDKIWVTVYEEDDDSYDIWAKEMNFPEERMVRLGKDDNFWE
                     IGTGPCGPCSEIYFDRGEEYGCDNPDCKPGCDCDRYLEFWNHVFTQFDRDEEGNYSLL
                     ENKNIDTGMGLERMGCIMQGVDTIFEVDTIKSILEAVEKLTGVKYGENPKNDISIRII
                     TDHIRAVTFLVSDGVLPSNEGRGYVLRRLLRRAARHGKLLGVKELFLQKLIDEVIKVN
                     DKAYPVLVEKESYIKKVVGIEEEKFNETIDQGTEILNSYIEVLKNEGKTVLSGQEAFK
                     LYDTYGFPIDLTKEILEEEHLSVDEEAFNEEMEKQKERARNARGNMDGESWKEDPLSK
                     LESTVDSTFNGYSEIYGEGTIEAIVKDDELVQSAEEGDKVSIVLDNTTFYPEGGGQVG
                     DCGLITNENLVLEVLNTKKGANNSIKHIGIIKSGRISNGDKVKTLVDRETRMSAARNH
                     SATHLLHKALREVLGEHVNQAGSLVTPERLRFDITHFEAISNEELKVIEEKVNNVILS
                     SLDIKCDIMNIKEAKEKGATALFGEKYGDEVRVVSMGDYSTELCGGTHLTNTSQVGMF
                     KILSEGGVAAGVRRIEAITGKAVYEYLKERDGIISEVCVNLKSKEDNLIQRISSLLEE
                     NKNLSKELHDMKAKMSLQSVDSIFDSKVEVNGVNLITNKFEGMDMDTLRETADNLRDK
                     LGSGVVVLANVVDDKVNFVVTATKDVLDKGIHSGNIVREVAKIAGGKGGGRPNMAQAG
                     ASDVSKVDQALSYASEVIKTQVK"
     gene            25885..26142
                     /locus_tag="KOU88_002178"
     CDS             25885..26142
                     /locus_tag="KOU88_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBK3212055.1"
                     /translation="MEKDLDYTMKFEGIPEDRMSVGDTIDFVYKALVEKGYNPINQII
                     GYLLSGDSSYITSHKNARAIIKKFERDEILEEVITHYLNRK"
     gene            26152..28323
                     /locus_tag="KOU88_002179"
     CDS             26152..28323
                     /locus_tag="KOU88_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212056.1"
                     /translation="MRKKIMSLFAIVIMIFVSTASYGFAEEKGKVIFIDMNRTNLGSM
                     MNIPILKNEIEKRGYVALMNIRGDQGTDDRRSYASMGAGTRASVTTEDYINFQKVDQD
                     TAKAFEVATGQKAKEINDLGINRSINENLEYGEYGANLGSLGKTLSENGLKTSVIGNA
                     DIIENNQLVKNRNLCLVAMDQYGRIDSGNIDNINKKDSKMPFGISTDYDKLLDETKKS
                     YKNSDAIFVELGDTYRLDMYRLNLNDNTYDIMKKNIVKNINKYLEQVFSMVGENDTVY
                     IASAFPSDLDYKNKRRLSPIIKFSGEGKGLLESATTRKAGIVANLDVGVDILGTFGLE
                     NKEMVGRSYTLVNKEDNISYLKSLYERIVSISSIRSTIINGFVGVISASWVIAMFAIF
                     FRNYMPHKERVFKVLKEFIKLGIIMPLSFMLAPLMNFKTPISISLGIFATTLILYLLG
                     RKLFKDNDIKHMGFFATLTILVIVIDSVFGTYLMQNNIMSYDAVIGARYYGVGNEYEG
                     VTIASAVFGLAVLLHYKKVSKLLVVIFSLIILITSAYPSMGANVGGAISECVAYLLFI
                     MLIYDIKIDFKKAVLLAVSAVVVVFAFAALDILSGSESHLGMFVQRIFLNGPGEILQT
                     FGRKIQMNMQLAQTSVWVNILLVGIGVIAVLIFKPSRHFRKIMNNFPILFKGFIASMV
                     GCIITLLVNDSGIVAASTASIYILIPLIIISINMIIFEKNN"
     gene            28529..28954
                     /gene="ruvX"
                     /locus_tag="KOU88_002180"
     CDS             28529..28954
                     /gene="ruvX"
                     /locus_tag="KOU88_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBK3212057.1"
                     /translation="MLDGRIMGLDVGDKTIGVAVSDLMGLTAQGVKTIKRVGKKKDIE
                     ELKAIIKEKQVNKIVSGLPKNMNGTLGPQGEKVIKFCELVKAETGIDVEFWDERLSTV
                     AAERSLLEADVSRQKRKKVIDMLAAVIILQGYLDFKINS"
     gene            29032..29319
                     /locus_tag="KOU88_002181"
     CDS             29032..29319
                     /locus_tag="KOU88_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBK3212058.1"
                     /translation="MEENIINLIDENGVESQFEIILTLEAEGKEYAILMPLDDEEAEE
                     ALIFRIDEDEEGEILIPLESDEEYETVVAVYTAIMEEEGLNYDEDESNGLN"
     gene            29601..30059
                     /locus_tag="KOU88_002182"
     CDS             29601..30059
                     /locus_tag="KOU88_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBK3212059.1"
                     /translation="MANTMDLLKDKLKETGFKITPQRRAIVEILLKHDHSHLSSEEIY
                     DLVRVDCPEIGLATVYRTMQLLDEIGLISKLNLDDGCIRYEISLHKEDCHNHHHLICK
                     NCGKIMEAKEDLLDNIEKEIQSLYKFKILDHDVKFYGLCDECNGVSDSEE"
     gene            complement(30176..30913)
                     /locus_tag="KOU88_002183"
     CDS             complement(30176..30913)
                     /locus_tag="KOU88_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBK3212060.1"
                     /translation="MRGKTHCAIGILTAIQTSLIFKIPISLVDILVSATFAVLPDLDK
                     SNSMVSNFILKNNVSKYIYRIFIYAVNIIIFFISININDNFYLSAIITFVAIIIIEAK
                     LTHTFLRKVFLSLIFILLAICLYIIEVEIYFTIFCLMLSIFPWLKHRSFSHSIFATII
                     VYFLLKQIELITNINNLSFYGTIGYASHMFLGDLFTKQGIPIFYPLSEKKISLGFLTV
                     GGPFSNFIEKSFIFVLIGLIIFSILKL"
     gene            31130..32806
                     /locus_tag="KOU88_002184"
     CDS             31130..32806
                     /locus_tag="KOU88_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBK3212061.1"
                     /translation="MQLFKKNTNKIKVMALGGLNEVGKNMTVVEYKDEIIVIDAGLSF
                     PEDEMLGVDIVIPDITYLVKNRDKIKGIFITHGHEDHIGALPYILKKINVPVYGARLS
                     IGLIQVKLKEHKMNNVKLNVIGPRQVIKLDNMEVEFLKNNHSIPDAYSIAIHTDQGII
                     YHTGDFKIDLTPIDGDVMDMHRICELSKKGVLLMLADSTNAEKPGFTMSEKTVGVGLD
                     ELFAKGNGRRIIVATFASNIHRLQQIINTAEKFNRKVAISGRSMVNVVGVAKELGYLD
                     ISDDMLIDLNDICKYEDSELVIITTGSQGEPMSALARMAFSEHKKVEIKSGDLVIISA
                     HPIPGNEKLISRVINFLFEKGAEVVYSDIADIHVSGHACQEELKLIHALVRPKFFMPA
                     HGEYRMLKRHAEIAEQLGMDKENIFVMQTGDVLELDKNSAKVANRIQTGNILVDGLGV
                     GDVGNIVLRDRKHLSEDGLMIVVVTISKDEGKVLAGPDIISRGFVYVRESEDLMDGAK
                     DIIKNVLNECEEKNIKEWAYLKNNIKENLKEYLYQKTKRNPMILPIIMEV"
     gene            33013..33213
                     /locus_tag="KOU88_002185"
     CDS             33013..33213
                     /locus_tag="KOU88_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore protein"
                     /protein_id="HBK3212062.1"
                     /translation="MDDVSRQNAIKALKQTKMEIAGEYGMNYEDAFEIIENASNKGVL
                     EGYFKKLEKKKNLGQGISRHLE"
     gene            33267..34430
                     /locus_tag="KOU88_002186"
     CDS             33267..34430
                     /locus_tag="KOU88_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBK3212063.1"
                     /translation="MKKLASTALAILIALTPLSFSFANNKENADANQLNISSKSAILM
                     DVGSGQILYEKDAHKKLPPASVTKVMTMLLIVEALDSGKIKLDDEVQVSETASSMGGS
                     QIFLEPGETQKVDTLLKGIAVASANDACVAMAEHLAGSVEGFVDRMNAKAKELNMNDT
                     HFANTNGLPVANHYTSAHDIALMSRELLKHEMISKYLTTWMDKVVVGKKQVTVGLANT
                     NKLIKHYQGATGVKTGFTQEAKYCLSASAKRGNTHLVAATLGAETSPERFNDASSLLN
                     YGFANYESVKLCSKGDNIATLTLDKADENKVKLVAKEDLNALIKKGSSKEFEKKIEIV
                     KNPKMPIKKGTVLGKIKICKDKKVIGEVELINTKDINKASYLQMLQRIIDNMI"
     gene            complement(34641..35063)
                     /locus_tag="KOU88_002187"
     CDS             complement(34641..35063)
                     /locus_tag="KOU88_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2000 domain-containing protein"
                     /protein_id="HBK3212064.1"
                     /translation="MENKNSKCVMVIDENLPMGIISNTAAIMGITLGKHAPETVGPDV
                     IDKTGNSHLGIIDIPVPILKGNKEIIKDLRKKLYTLEFNDLTVVDFSDVAQSCNLYEE
                     FTQKIASVPEDELQYFGIAIYGNKKKVNKLTGSMPLLR"
     gene            complement(35084..35920)
                     /locus_tag="KOU88_002188"
     CDS             complement(35084..35920)
                     /locus_tag="KOU88_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK3212065.1"
                     /translation="MRQEERTVCFDRELKIEAYTFKGIMQKFPNHFHEHYVIGFIEKG
                     QRYLSCKNKEYTTSTGDLLLFNPFDSHTCEQIDDKVLDYRCINIKPEIMKKTVFEITG
                     KNYLPKFNQPVIFRSELVPLLQELHYIIMEEELDFKKEELFFFLIEQLIEEHTEPNLQ
                     SNLENTNIEIQAVCDYLENNYAEHIVLDELSTIAGMNKYSLLRNFTKLKGITPYRYLE
                     NIRVNKAKKLLEKGVEPIDAAIQTGFVDQSHFTNFFKNFIGLTPKQYQNIFINDDSNN
                     FK"
     gene            36218..36814
                     /locus_tag="KOU88_002189"
     CDS             36218..36814
                     /locus_tag="KOU88_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HBK3212066.1"
                     /translation="MLSMNIGEIVASLVGIAMAISIHEFGHAYSAHLLGDDTAKAYGR
                     MTLNPVRHVDPIGLLAMFILKIGWAKPVPVNPNNFKNYKIGNLIVSLAGVFCNVLTAI
                     LCVIINKYVHMYAINTIAGYVLLYSMGFAAFNLLPIPPLDGWGVISTFVPYKWNEYLY
                     KFESMSYIILLIALFTGIYQIILSPIYTVLLKIVYLFV"
     gene            36844..37563
                     /locus_tag="KOU88_002190"
     CDS             36844..37563
                     /locus_tag="KOU88_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBK3212067.1"
                     /translation="MKYNIQLQVYEGPLDLLYDLITKHKIDIKDISIIDITKQYLNYL
                     KMLDKMDLEITSEFITMASKLLEIKSKYLLYKQKDEEEDPRIELMEKLEEYRKFKVAS
                     QDIKENITYVNERFYRNKEEIIIDDNVDLEDISIEAIKNILPYIFKVKTSQIENANDE
                     KLDKIVRKKIISVEEKILYIRDIIKEKIEVTFTNIIKSYENDEIIATFLSILELIKEK
                     EIVVVQDIFFDDILIRKSSEC"
     gene            37565..38104
                     /gene="scpB"
                     /locus_tag="KOU88_002191"
     CDS             37565..38104
                     /gene="scpB"
                     /locus_tag="KOU88_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBK3212068.1"
                     /translation="MKREDIKYIIESVMFAYGEPISIKELNYIINKELSSKEIEIMLN
                     LLIEEYREQNRGIQIIKLENKYQMCTNKDYAEYIKKIIEPKKKKSLSQATLETLTIIA
                     YKQPITKVEIEDIRGVKCDKVLQTLFENELIREAGRLNKIGKPIIYKTTDEFLKLLNI
                     ESLEELPPIENYQEVVTNE"
     gene            38266..38895
                     /locus_tag="KOU88_002192"
     CDS             38266..38895
                     /locus_tag="KOU88_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2953 domain-containing protein"
                     /protein_id="HBK3212069.1"
                     /translation="MELNELFNFKYLIIAVIFIISVTMLILISHINILIIADIKNKDI
                     CLKLNIKYMFNLININRQLYPAENSKNNDKKEGMKNNIDSSILLADDLLSIYRLLKKI
                     KIHELYSNINFGTGNIGLTSSVYVLINTLYGNLFNMIDAEKMYLNVNPDFTKDYVLGN
                     IRIHIRPRIKALFNIIIMINKIMNKNKGNKEGDSNESNRFDTESYGNNS"
     gene            38849..39277
                     /gene="ytfJ"
                     /locus_tag="KOU88_002193"
     CDS             38849..39277
                     /gene="ytfJ"
                     /locus_tag="KOU88_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerW family sporulation protein"
                     /protein_id="HBK3212070.1"
                     /translation="MRATGSIQSLMETTLETIKGSIDANTIIGDPIKTDTTVVVPISK
                     VTIGFGIGGGEYSKGYDDKDREIELKNEKSDTNFAGGSAGAISVQPVAFVVVESGETR
                     IMSLDSNINLVDNILSITPRVLEKIQNISQSNKNQDKNNM"
     gene            39525..39965
                     /locus_tag="KOU88_002194"
     CDS             39525..39965
                     /locus_tag="KOU88_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3212071.1"
                     /translation="MSDKELSILLLESMNNFHNLIKIINNERYKKDKVLTERQFFALV
                     KIRKHDKIELKNLSRDLHVSTSSLCILLNKLVEQEYVYREEDSRDRRNTFYGITKNGE
                     KILDNEILKFVSIISDKMDCLDIDNKDKLFTSLEESKNIIEQLF"
     gene            39981..41432
                     /locus_tag="KOU88_002195"
     CDS             39981..41432
                     /locus_tag="KOU88_002195"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBK3212072.1"
                     /translation="MNIKYSKEILKSLENAITVVALFEGEDVFTTFDKINMISRNFNS
                     KENSIDTVTLVENNNLVNVCLVGFGKRELLNREKIRIIGGNLCKKLKNILKNEAYKSS
                     DVNVLNLNLNSDEIGCFVEGILLGNYKFDKYKTKSKDFERKEVDTITIFTEKEVECQI
                     EKAKILANSTIIARNLVNEPSNVIYPKTLAVETVKLGAEFGFNVDVYEEEKIKALGMD
                     AFFAVSRGSINKPRFIVMRYFGDKESTDILGLVGKGLTYDTGGYSLKSNASMLDMKTD
                     MAGAASVIGAMCAISQSKLKKNVIAVVAACENALSGGSYKPGDIISSMAKKTIEVLNT
                     DAEGRLTLADAIYYIINNEKVTKVVDVATLTGAALTLLGNIATPIVTNNDDFYCELEK
                     AATLSGERVWKMPIYDEFKDMIKGEEADLKNTGGKNAGCITAGAFIGEFVGNTPWIHM
                     DIAGTSTSSKSIGYKAKGATGEPVRTLYYLAEI"
     gene            complement(41523..42191)
                     /locus_tag="KOU88_002196"
     CDS             complement(41523..42191)
                     /locus_tag="KOU88_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwaF family protein"
                     /protein_id="HBK3212073.1"
                     /translation="MFKIFLFSSEQFVSLFIFGLFLYYCPKLTKNILPYSYTVEKIIC
                     TLLVIIMALEQLLLISSGNYSTLNSLPIGINYICIYLCIAILIFKQYHLFNIFFSWSL
                     VCSVGELIFSKNLGYEFPSLIYFIFILSKCLIIYADIYMVDVRKFRVNRYALRDNLAI
                     CFIYFSFIFLLNTFTNSRYYYGFLSHSTTAIFTFIFVTSIMYIPALLFNRDTFILEKK
                     KKSK"
     gene            42460..42600
                     /locus_tag="KOU88_002197"
     CDS             42460..42600
                     /locus_tag="KOU88_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212074.1"
                     /translation="MGIIESASKLAEMVHLLAVEKGITDIEAWDEAVKEYSKIYEERR
                     NE"
     gene            complement(42775..43095)
                     /locus_tag="KOU88_002198"
     CDS             complement(42775..43095)
                     /locus_tag="KOU88_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBK3212075.1"
                     /translation="MKLKTISLPELNNLDPTLESTFIKMGEEQGELAECIGKFRNLSG
                     ENNDLDEVDIIKKTAKELMDVAQTCVTMMFKLEEQYGINLDEIRKEHIKKLEKRGYIK
                     NMDK"
     gene            complement(43215..43952)
                     /locus_tag="KOU88_002199"
     CDS             complement(43215..43952)
                     /locus_tag="KOU88_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBK3212076.1"
                     /translation="MDANSLKDLIANHNNIVFFGGAGVSTESNIPDFRSSTGLFSQKL
                     NKQFTAEQLVSHTFFVRYPEEFFEFYKDKLIYPNAKPNNAHIALAKLEEMGKLKAVIT
                     QNIDGLHQMAGSKNVLELHGSVHRNYCTKCGKFFDLESMLNLGGNIPYCDNCGSIVKP
                     DVVLYEEALDSDVITKTISAISNADLLIIGGTSLAVYPAASFIDYYKGDYIALINKAN
                     TVYDKSASLVINKPIGEVLYEAVLRQI"
     gene            44167..45990
                     /gene="acd"
                     /locus_tag="KOU88_002200"
     CDS             44167..45990
                     /gene="acd"
                     /locus_tag="KOU88_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HBK3212077.1"
                     /translation="MKKKAALATLAMLPLGVVNAHADGDIGIVTINYLNVRNEPTAES
                     SIAFVAKKDDKVLIKDSSNGWYKIKAESGQEGWASSKYIAKSNSDSLRTSTNKEKQVI
                     SNSLNMRNGAGTSYRVITVLKKGQKVEVISESNGWSKIKYDGRLGYVSSSYLGDVSNS
                     TNKSKTKQVNTTSLNVRSGPNTSYGLLGKLPKGSKVEVISESNGWSKIKYNGKDAYVS
                     SMYLSDVSQSNSDNSSQSNDKKNTDKVVNTASLNVRSGPGSTYSKLGKVYKGSKVTVL
                     SESSGWAKINFNNKEAFVVGNYLSTSADTSNNNSNSNSDNSSNSNGNNSSSSGQVNGM
                     SGISGAKIDYKSLSYTLESHISKQVEKAASGGNVIAPSNRKSTPSPEFSTFSAQRTSS
                     FVNASSSDIEYYLNPKNFTNTTKGMMQFLKINSYRDGISESSLNSYLNGLSSSVFKNQ
                     GAAFINAAKKYNIDVVYLVSHAMWETAYGKSTLAQGQTLTSYKGQPLSKPVKVYNFFG
                     IGAIDKSANVSGAEAAYSNGWTSVEATIDGSAKWISQNYVNSSKYNQNTIYKMKWNYD
                     YTWHQYATDVNWANGISGIMENLIGLYGGGSSLVFEVPQYK"
     gene            46205..50503
                     /locus_tag="KOU88_002201"
     CDS             46205..50503
                     /locus_tag="KOU88_002201"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBK3212078.1"
                     /translation="MESIKEYLDKLEINNSGLGKQLKEVYINRVVYFKEDKIVYFYLT
                     SKDIVSHELLDKFKEELMYKLDYFKDMRMKIRFTGLERKSNKDVIKKYWNNILYILKY
                     LCPSIAGWYKQVEFLCLEEELKIKLPKGIFYERLMKKNVTYVLKTVLSEELGLDLNIT
                     IEKAVDEKVNKERLIRINDREMEEKIRALEIGKVNNCEENEEESYVIKSDVDENLIYG
                     DNANAMIENIVELNASSGTVAVVGDIFDVDTKELKNGKILMIASITDYTSSISCKLFL
                     TDTNKDGVLENVKKGAYLKIKGDIVYDTYQREISMMISGIRKETRIEREDKSEEKRVE
                     LHAHTQMSSMDAICSVKKLVERAAKWGHSAIAITDHGVVQGFPDAMNAGKSNNIKILY
                     GVEGYLVEDDSLIIEDANDKELSQTFVVFDIETTGFSNTNDKITEIGAVKIENFKIVD
                     RFSELINPEKDISYKIQELTGITNELIKDKPTIEEVLPKFMEFVGDSVLVAHNAEFDT
                     GFISQKCREQGLLYNNKKVDTLMLARVMLPNLKRHRLNVVAKELGIPLLNHHRAVDDA
                     EATALIFNKFLQMLTEKGAKTLSDVNNILGKIDYTKLSTNHITLIAKNSIGIKNLYKI
                     ISDAHVNHFFRAPRILRSVLNEYKEGLIIGSACEAGVVFQAVKKNVSDEEMKKIIDLY
                     DYIEVMPIDNNRFMIDKGEVKDEEELRELNRKLIDTAKKFDKIPVATGDVHFLDKHEA
                     VLRKVLKYSQGFKVDEEETYLHFRTTDEMLEEFSYLGEELAYEVVVENSNLIADMVED
                     IKPIPDDTYPPIIEGSDVELREMCYKKAKRIYGDPIPEIAQKRLDRELNSIISNGYAV
                     MYIIAQKLVAKSLSDGYLVGSRGSVGSSFAATMSDITEVNPLPAHYICENEDCKYSFF
                     YEIGEWGSGVDLPDKDCPKCGRKLAKNGHDIPFEVFLGFEGDKEPDIDLNFSGNYQPT
                     IHKYTEELFGEGYVYRAGTIGTVAEKTAFGYARKYVEENNISVPNAEVLRLSNGCTGV
                     KRTSGQHPGGVMVIPDYKDVYDFTPIQYPANDTSCGVITTHFDYHSISGRILKLDILG
                     HDGPTIIRMLEDMTGINITEIPLDDKETMSLFTSTEALGVTPEEINCPIGCLAVPEFG
                     TKFVRQMLLDTKPTTFAELVRISGLSHGTDVWVNNAQDLVREDIVGLKDVISTRDDIM
                     NYLIFKGLPPKMSFTIMESVRKGKGLKPEHIEEMKKNNVPEWYIGSCKKIKYMFPKAH
                     AVAYVMTSFRIAYCKVHYPEAFYATYFTTKVEDFDADLIVKGLDAIKSKINEIESLGN
                     DATTKEKGMLTVLEVALEMYARGIKLLPVDIYKSDATEFIVVGEKTLLPPMAAIQGLG
                     GNAAINIQNERKNGEFISKEDLRKRTKISKTVIETLTNHGSLENMSERNQLSLF"
     gene            50707..51168
                     /locus_tag="KOU88_002202"
     CDS             50707..51168
                     /locus_tag="KOU88_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBK3212079.1"
                     /translation="MKKNLEATIEEIVTKITDEHGFEMVDVEYVKEAGEYYLRVYIDK
                     EEGISLNECELVSRELSPILDEKDPIKENYFLEVSSPGLDRALKKDRDFVRYQGRDVD
                     LKLYKPLNGCKQFEGELVGLTEDNNIKIIANGKEMEFNRKDVAIVRLAIKF"
     gene            51198..52352
                     /gene="nusA"
                     /locus_tag="KOU88_002203"
     CDS             51198..52352
                     /gene="nusA"
                     /locus_tag="KOU88_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBK3212080.1"
                     /translation="MNHEFMEALDELVVDRGIDKEILIDTIEQALLTAYKKNFGSAQN
                     VRVEFDRDKGDIKVFSQRVVVDESDLYDTFLEIELADAREINPNYELGDIIEHEVTPK
                     NFGRIAAQTAKQVVVQRIREAEREIVYNEFIEKENEIVTGEVARANKNVVYVNLGRIE
                     GIMTQSEQIPFENYKAGQKIKFYILEVKKTNKGPQIVVSRSHPGLVKRLFEEEVPEIY
                     EGIVQIKSVAREAGSRTKMAVRSIDEKIDPIGACVGPKGLRVKNIVDELGDEKIDIIK
                     YSEDPAEFISAALSPSKVVRVDIDEDEKSALVIVPDYQLSLAIGKEGQNARLAAKLTN
                     WKIDIKSESQAEQEMLNLENSKEIEAEDVEAEFIDQEELDTSEDNFSEEE"
     gene            52359..52640
                     /locus_tag="KOU88_002204"
     CDS             52359..52640
                     /locus_tag="KOU88_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBK3212081.1"
                     /translation="MILKKVKKVPQRKCIACQDRDSKKELIRIVKNKEGKIFLDPTGR
                     ANGRGAYVCKSSECLKKAIKSKALNKAFKIDVPDEVYDNLLMELEEYEK"
     gene            52630..52941
                     /locus_tag="KOU88_002205"
     CDS             52630..52941
                     /locus_tag="KOU88_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HBK3212082.1"
                     /translation="MKNNKEKVLSFLGLATRAGKIVSGDDSTLLDLKKGKVNLILIAE
                     DASNNTKKLFKDKSTFRNIPYLFFSTKEEIGFAIGKSPRAVVGIKDENFSKKIIELIE
                     I"
     gene            52963..54903
                     /gene="infB"
                     /locus_tag="KOU88_002206"
     CDS             52963..54903
                     /gene="infB"
                     /locus_tag="KOU88_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBK3212083.1"
                     /translation="MSKTRVYQIAEELNISNEELINKLAELDINVTDKDSVLEGEELE
                     LALEMLGEDLSQENGNVIEIDGKLTVQVLATKLDKSPSEIIMKLMKMGTMATINQEIS
                     FEIAALAAKDYGFELTVAESDDTEALEIEALMEIEEDKEEDLKPRPPVVTVMGHVDHG
                     KTSLLDAIRKTDVISGEAGGITQHIGASEVKINGHKIVFLDTPGHEAFTSMRARGAQV
                     TDIAILVVAADDGIMPQTVEAINHAKAAGVPLIVAINKIDKPGANPDKVKQELADQGL
                     LVEDWGGEVIAVPVSAKKKEGIDTLLEMVLLVAEMEELRANPNKRAVGTVIEAELDKG
                     RGPVATVLVQGGTLTVGDPIVAGVACGKVRAMINAKGKRVKTAGPSTAVEILGLSEVP
                     QGGDQFVEVPTDKIARSVAARRQQIVRDEMLKSTQRLSLDALFSQMSEGSIKDLNIVI
                     KADVQGSVQAVKQSLEKLSNEEVQVKVIHGGVGAVTESDILLAAASNAIIIGFNVRPV
                     PGAESLGEKENVDIRTYTIIYKAIEDIQAAMTGMLDPEYVDEETGKAEIREIYKISGV
                     GTVAGCYVTNGKIFRNCKVRLVRDSIIIHEGELAALKRFKDDVKEVNSGYECGMSFVN
                     YNDIKEGDIVEAYITKEVERKL"
     gene            54946..55326
                     /gene="rbfA"
                     /locus_tag="KOU88_002207"
     CDS             54946..55326
                     /gene="rbfA"
                     /locus_tag="KOU88_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBK3212084.1"
                     /translation="MASYNRTRRIAEEIRKVVSTMLINGVKDPRITSMVSVTDVEVTN
                     DLRYAYVYVSILGGDEESTLTGLKSAGGYIRREVGKNIKLRYIPEIVFKLDDSIEKGM
                     YMDSLIKRVNEKNAQQNEDENYDE"
     gene            55307..55984
                     /locus_tag="KOU88_002208"
                     /pseudo
     CDS             55307..55984
                     /locus_tag="KOU88_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438308.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
BASE COUNT        22554 a         6049 c         9895 g        17743 t
ORIGIN      
        1 ataaaaaaat aaagtatata agagtataat ttgactttta tatacttttt tatattattt
       61 ttgagttttt taggaagata ttttacaagt taagaaaact ataaggagtg ttatattgaa
      121 tataaaatag tataatatat attatgttag ataattaata tgaaaatata caaatatata
      181 aaaagtttgt ttagagttat agttaatgtg tgtattaatt taatactaat ttattggagg
      241 tttaaaaatg aagtacataa taaaaagaga tggtacaaaa gaacttttta gtaaaagtaa
      301 gattgaagat gctgtctata aagctagtat aaatagtgaa ggtggcgtag atagagagtt
      361 ggcatatgat atatcaagaa aaatagctaa tgactataat tctatggaaa aatgcttatc
      421 cgtagaagaa atacaagata tagttgaagt actacttatg gaatcaaata gaaaagatat
      481 agcaaaacac tacatattat atagagaaag acgctctgaa ataaggacta aagcttggga
      541 gtttgatgaa ttacaaaaat caatatggaa gaacaagtat agacataatg gtgagagttt
      601 tgatgaatgg ataaagagaa tttcaaataa tagttcaaga atatcaaaac taataagaca
      661 aaaaagattt ctatttgctg gaagaatttt agcaaataga ggattacaga aagagggaaa
      721 aaaagtaaca tattctaatt gctatgtaat agaaccacca aaagatagca tagaagatat
      781 atttgatact gcaaaaaaac ttgctagaac ttttagttat ggtggaggag ttggaattga
      841 tatttcaaag ctaagaccaa aaggagcgaa agttaacaat gctgcaaaac atacgactgg
      901 agcagtctct tttatggaac tttacagtat gacaactggc ttaattggtc aaagagggag
      961 aagaggagct cttatgattt ctatggatgt aaatcatcca gagatagaag actttataga
     1021 tataaaaaca gatttggaga aggttactaa agcaaatatt tctgtgagag taacagatga
     1081 atttatgcaa gctgtaagag aaaaaaagtt atataattgt acttttgaag ttgaaactac
     1141 tggagaaaaa atagttaaga tagtaaatgc ttatgattta tttaataaat ttgtgaaaaa
     1201 taactgggat tatgcagaac caggtatatt gttttgggat aaaataaaaa catataattt
     1261 tatgagtgaa gataagaact tttgcttttc aggagtaaat ccttgtgcag aagaaccact
     1321 tccaagtgga ggaagttgtc tacttggctc aataaacttg tcagagttta taatacaacc
     1381 atttggtgaa catgctactt ttgatattaa taaactaaaa tcttgcgtta gagaagctgt
     1441 agtagcttta aatgatgtct tagatgaggg attgaacttg catccattac aagaacaaag
     1501 agatagtgta cataagtata gacagatagg tttaggtgta atgggtatag ctgatatgct
     1561 tataaaaatg ggaataagat atggttctga tgaatcttta gaactatgtg atttaattgg
     1621 taagactatg ttaaatgaag ctgtgaagca atcagcatta attgctaaag aatatggaac
     1681 atttagtgag tataaatatg aaaatatttc taaatctaag ttttttatag aaaatctaaa
     1741 tgaagacact aaggaaatgg ttaaaaagta tgggcttaga aattcacaac ttttaaccat
     1801 acctcctaca ggttccatat ctacaatgat aggtatcagt ggtggaatag aacctatatt
     1861 taatctttca tatataagaa aaactgaaag cttgcatgat gaggatgtgt attataaagt
     1921 atatactcca attgttaaag agtatatgga caagaaaggt attacagatg aagaatgttt
     1981 accagatttt tttgttactg ctatgaatat aggatatgaa gaaagaataa acatgcaaaa
     2041 agtatggcaa aagtatattg atgcttctat atcatctaca ataaatatac cttttgaaac
     2101 tacagttgaa gatgttttca atatatatat taaggcatgg gaggctggtc ttaaaggagt
     2161 aacaatattt agagatggat gtaaaaggag tggaatttta ataaatgaaa aaaaggaaga
     2221 aaataataaa gaagataaaa aagaaaatag taaaaaagaa tattataaaa ataataaaaa
     2281 agaaaaagat aataaagatg aaaaagccaa agaaataata aataaaaatt ttgaagaaga
     2341 tgaaaaattt gtgtgccctg agtgtggaag tgaaggaatt gcacatacag gtggatgtag
     2401 tatatgttta aaatgtggct atagtggatg caattaaact ctaattaaaa aattttaata
     2461 tatttaaaaa ttaaattttt aaaaacgaaa gatgagggaa tggtatgcag gataaaagtg
     2521 tgagggagat taaagaaata atagagactt tagaagtaga aaaatatatg gaatatatag
     2581 agctgttaag agttgatgaa agaaaatctg tacaaggtct agctataaaa ctagcaaaaa
     2641 agctggataa tattagaaaa gaagaagaaa gattggaaac tataaatata tttgagaacg
     2701 aaggctatga taaaggttat ttatatattg gaggaattga tgaggcggga agagggccac
     2761 ttgctggacc tgttgtagct tctgttgtag tatttaaaaa agataccaaa atagaaggtg
     2821 taaatgactc taagaaactg agtgaggcaa aaagagatga actttttgaa gtaataaaag
     2881 aagaagcact agattatgga ataggtatag taaacaatga agaaatagat gaatttaata
     2941 tattaaatgc tacatatatg gcaatgaaaa aggctataaa ttgtttaaaa aaagcaccag
     3001 attatttatt agttgatgca gcaacaatac caggtattga catatctcaa aatccaattg
     3061 tgaaaggaga ttcaaaatct atatcaatag cagcagcaag tatacttgct aaagttacta
     3121 gggatagtat aatgtaccaa tatgatagag tatacccaga atatgggttt aaatctcaca
     3181 aaggatatgg aactaaagaa cactatgaag ctattgaaaa atatggcata actcctatcc
     3241 acagaaaaag ttttttgaaa aatatactgt aaatataata tgatataatg tatataatat
     3301 aaattactat agttaatggg ggattaaaga tggaatataa tggattatta aaaagtgcta
     3361 gagaaaattt aaatggaagt tgtaaagttt gtaaggtttg taatggggtt gcttgtgcag
     3421 gtgaagtgcc tggcatggga ggtaaaggaa gtggttcttc ttttatagaa aatagcaaga
     3481 gtttagaaaa agtaaaagta aatatgagag taatacatga tgtatcaaat cctgatacat
     3541 ctatagagat gtttggaaag aaaatgagtg cacctatatt tgcagctcca gtaacaggaa
     3601 ctactttaaa tatgggtgga aaaattaatg aaagagatta catagaacca gtagttgcag
     3661 gatgtgctaa tagtggtatt tatgcaatgg ttggtgatac ggcagtagat gcttttttaa
     3721 tggaaaattt agatgtagtc aaaaagtata atggagctgg aattgtattt attaaacctt
     3781 gggataatga aaatattata aaaaagataa gattagctga agaagctggt gcatttgcag
     3841 ttggagttga tatagatgcc tgtggtctag taactttatc attacatgga aaaccagtac
     3901 ttcctaaaaa tgttaaacaa ataaaggagt tagtaaagtc tactaaacta ccatttatat
     3961 tgaaaggtat aatgactgtt gaagatgctt taatggcagt agaagcaggt gtggatgcaa
     4021 tagttgtatc aaatcatgga ggaagagtgc ttgactgtac accaggagca tgtgaagttt
     4081 taccaaaaat tgctgatgct gttaaaggta aagttacaat acttgcagat ggtggagtga
     4141 gaactggttt agacgtacta aaaatgatag gtttaggtgc agatgcagta ttaataggaa
     4201 gaccttttgt gactgcttct tttggtggtg caactgatgg tgtagaaact tatgtaaata
     4261 aacttcaatc agagctaagt agttctatga tattaactgg atgtcaaact ataaaagata
     4321 ttgatggaaa agttatatac aaataaaatt ttatacaaaa aagaggaaaa atcattttaa
     4381 tgtagaataa ttgtacaaag ggggaattta tatgagtaga aaagcttatg aagaagcctt
     4441 agtagaatta gaaaaattta ttgatgaaag aaaagaaata attaaaagtg cggaggactg
     4501 tattgataag tacatagttg acagaacgct accttttgat tacaaagata aatgtgtgga
     4561 atggcaacaa gagttacttg atattgcaga ggcacaagtt ttagaagcaa atgaattaag
     4621 tgtattatta caagagaaaa aagaacttga agaagattaa attttattag ctaagagtaa
     4681 atcagtaata tgatttactc ttagtttttt ttatttgaat aaaatacatc tatctaattg
     4741 agataacttt attaatatta gattaggcag tttaaaataa gctaaagtag catggatgat
     4801 tagtataaaa aataaaacca gtttaaaaaa ctggtttaat ttgtattctt tgaatttaat
     4861 atatgttttt tcatttcctc taataccatt gtataggatt tacattgagc agcagctaat
     4921 tctgataaag caaatttttg agctttattt aaaaactcct tatctgtgct acacaattgt
     4981 tttgaactgt cttgtatcat aagcattttg attaatttta caatttcaaa aacatctcct
     5041 gaatgaaatt tatcttggta cagtttaagt ctttcttttc tatcaaaaat ccatacacca
     5101 tctgttttat taatagattg gataaaatta tcaacatcat ttccatccat aactggacgt
     5161 atgccaattc tatctgcatt tagaactgga atcgaaattt taaggttact attaaaaatg
     5221 acacttaatt catagtattt ttgcatctca tgatttattt tctttgttac aatatcattt
     5281 acagagcagg ctccctcttt tggatacatt acactttcac caattttata catatgctag
     5341 ttatacctcc aaattgaatt ttagatattg caacttaggt acaatgcttt aattatctaa
     5401 tgattaatat tataacataa ataacttgac aagtcaaaaa tattaatata taatataaag
     5461 tttagacttg gtgatgtgtg aaactaaaga gaaaaatata agataaaata atttaatatg
     5521 ttgaaatatt cttttacaat tatataaaaa tagatactaa ttatatttaa taattattag
     5581 tttttagcaa aatctcttag tttaagactt cctgcagtta caaatataat tccaattaat
     5641 attagagcta ttatatttat taaaatacta ccattgtttt taatagcatc tatagtccaa
     5701 taaaatggtg tgaactttga aagattagtc ataaaggata atttatccat tgatggtatt
     5761 agactagaga tagatatagc tagacctatt aaagaataaa atgtagatat aagacttata
     5821 gaactttcat ttttaaatac tctagctacc caaaatacaa atccagtgga aacaaaacta
     5881 tttgctagta caatcatcaa tacattcaga ctcaaattaa agtcttctat aattgaaaaa
     5941 cataatagag caaaagtgta tacaattgat tgaataaaaa atagtcctaa aaatatactg
     6001 aaaattattt ttatatcttt attatctgta gagataagtc tttttagcac atttgatttt
     6061 tttaatgtaa ataaatcaga agcaagatgt gccgcattaa tatacataaa atagcatatc
     6121 aagaagacta ctaaaaatga acctttattc ttatctggtt tgttatcaat tatatttgtc
     6181 tttgtcaatt tatcatctat atttttatcc actttcaatt ttaacgattt agtaataaaa
     6241 gattctattt gtgattctgc ccaaagacta ccaccaccat tttcaatttt aaagcattta
     6301 actacaggtc gttgtaattt atctatacta tttgaaaaat ttttatctaa aacgaataca
     6361 gcagaaacct tattattttt taatagattc atagccttat cttgttcatt taatctaaat
     6421 gaattttctt ttaatttaga actatttatt aacttatgtt catactttcc tgaagagtca
     6481 gatacaattg ctactggaga aaagtacatt gattgatttc ctgagttgtt gataaaaaaa
     6541 ttaagtgaaa aaattagtat aataggaagc ataaccatgt taattaaaag agtatgattt
     6601 tttagatatc tttttatatt tgcaatagtt aatctaatca ttattaaacc tccctccatt
     6661 tatatttttc ctttacaata gcaagtgcaa ttaatattgt agagataatt aaacatgtga
     6721 aaattaaatc tcctattgaa tctatagttt taaatgtttc ataattacta aacaattctc
     6781 ctattaaata ggtaggagat aaacttgtaa gcttagtaaa tgtatcactt atcatactga
     6841 agatacctcc aaaaattgtc tgtaaaaaga gtaatgcata aactattgct gtaccgtatt
     6901 ttttgctaaa aaagctggtt acaaaggtag atattgaagt cataaaataa gatgataaag
     6961 cacaaagtag gagcaatatg gcaaaattac ctttaaatgt tattccaagt attctaaaga
     7021 ataaaacata taataataag aatataaatg aataaatcca taaacctaca aagtcataaa
     7081 ttaagaattg tactctagtt ataggcatag aataaagtct ttttgaaagt ccctttgatt
     7141 cacttatata atttgataaa atattgttca ttataaaaat tattacaaga aatcctagtg
     7201 aaactaaagc aaagtattca taagagctct gtttaacatt gttatttatt atagaagtat
     7261 caatagaatt tttattaaat aatttagaaa aatcttctga acttattttc tgagaattat
     7321 ttaaataaaa tttttcatgg taagtatcta atatatcttg aagcaatatt gcaatatcat
     7381 cacgagttcc aagtttttct atgtttagag tatttgattt ttcatttaat aaactactct
     7441 catagccttt aggtatagta agctttaatt ctgccttaga atcatctttt ttaactgtta
     7501 atatataaga taaatcattt ttcaaatact ttgtcaaatc atttgataat cttgtgttat
     7561 ctttgtcata tataacaatg ggggtagatt ctgtttttat agggttttga aacatgcttt
     7621 ctgtaaccat accaagaaac caagataaaa tcagaggtaa agctaaaaaa tatattaaat
     7681 taagtataaa ggagcttttt aaacccttta gcatagtttt tacactcatg tataatttca
     7741 taaaatcacc tccattagtc ccttaaattt ttgcctgtta gatttaaaaa tacatcttct
     7801 agactaggtt cttcataaga aattttcatt atttttgaat cgtttttgtc aattatagag
     7861 agtatatctg taagttgtaa ttttttatct atatccaatt ctaataatga attattttct
     7921 aaaacagata taacaccttt agtatttttt aaatcaaaga taagttgggc atttatattt
     7981 tttatttcca taatcaattt tgtatttgta gatacgagtg attttaaata atcattatct
     8041 ccaaaagcaa tttctttacc ttcatccata ataaaaattt tagaacaaag gtgttcaact
     8101 tcttccatat aatgggaagt atatattaca gtagtttcat gttttttaga tatatctttt
     8161 ataaaattga aaatatgatt tcttgattgg gggtctacac ctacagttgg ttcatccaat
     8221 attaatattt taggatgatt taagagtgct attccaatat ttaatctcct ttgcatacca
     8281 ccagataatt ttttgacctt tttctttttg acttcagtaa gacctgtaac ttctaatgct
     8341 tcaatgattc tttctttaag tagttttccc tttaaaccgt agaaagctcc aaagtactct
     8401 aagttatcaa aaggagtaag agtttctata attgctaatt cttgtggaac taaccctatt
     8461 atagactttg cttttatata atcttttgat aaatctaaat cattgatttg aatactacca
     8521 ctatttggta acataagatt tgtaattata tttataagtg tagatttacc tgcaccattt
     8581 gggccaataa gtccaaatat ctcacctttt ttaacagaaa agctgatgtt atcaagtact
     8641 aatttatcat taaatctttt tgttatatta tttactctga ctatatccat agtaatccct
     8701 ccaaaataat tttgtataag ttaaaaagct ataatattat aataaagaat tgtgaattat
     8761 aattctatta ctataagtca ctaaaaaaag tgacttaagt cactttatat ttttagattt
     8821 attctattac aattttattt ttgaaagcaa agattgctag ttgagttctg tcacgaagtt
     8881 ctagtttagc taaaatatta gttatgttat tctttattgt accttcagat aagaatagtt
     8941 cttgacttat ttctttatta ttaagtccat ttgcaattag tctaattata gatatttctt
     9001 tttctgttaa attgtacatg tcataaagat gctcttgttt aaccgttttt tcagaggtca
     9061 tgattttttc agctacactt ttatcaagca caatattgcc aaaaaatgaa gaacgaatcc
     9121 cttcatgcaa tacttcatca gagctatctt ttaaaaggta tcctgaagca ccaaacttca
     9181 tagcatcttt tatatattca tcatcattaa aagttgttaa aattaataat gttatagaat
     9241 tattatattc ctttataagc cttgtaccta gaaccccatc acatactttc attcgtatat
     9301 ccataagaac tatgtctaca tcattcattt tacaaaattc taaagcttca tatccattag
     9361 aagcatctcc tacaatttct aaatcattat aagatgataa tataatttta agaccttttc
     9421 taattaattt ttcgtcatct actataagaa ctttaatttt attcaaaaaa atcaccccct
     9481 gaaaatttag gaaaagaagc tctaattgtg aaaccattat tagaattatc aaattcaact
     9541 ttaccattta attcatatat tctctcattg atactattaa gtccatttcc tttttttata
     9601 ttgccacatc ctataccatt atcactaata gtaattataa gatttgaagt attgaatgta
     9661 ataaaaattc tgatttcagt tgcctttcca tgcctagatg agttggaaag ggattcctgt
     9721 atgagtctat ataaagctat agattgattt ctggataagt tccaagtatt ttttgaaata
     9781 gttaatttaa cattaatatt tgtaagctta ataaagcttt taactaattc tttgatttta
     9841 aataaacttt ggtaattttc atattcaaca ggttttaact cagatatagc ccttcttaca
     9901 tcttgaaaac tttcagttac aaattctcta agttcatgta ctaagtcata aattagaggt
     9961 ttgtctttta agagtttttc tatagcattt aattgtatta ttgttgtaga aagagaatgt
    10021 cctacactat catgtatttc tcttgatatt cgatttcttt cttttaaaat tgctaattct
    10081 tctatagaac ttgcataagt ttccaaatca gcattaactt tttttaattc atctttagaa
    10141 attctaagct tatcataaag attttgactg tataattttg ataaattctc attttctata
    10201 tatatagaaa gtacagttat aattagcaat atagagcttg actccagtgc caaatatata
    10261 tttttatcta aactaataat aagagaagat attataacaa aagagaacaa tatgtactta
    10321 tatttttcct ttattaaaaa tgatatatct aatattaaag gaacaaagta aatcgaatta
    10381 aaagtttttg tataattaca aagtataaaa attaatataa gttctaaaaa gtaagaaata
    10441 agtataaatt tattctcatt tgataaagaa aaaaatctaa cttgattatt tattataatt
    10501 agaaataata ttatcatagt tatgaccgga tacaatgtat tttcaacatt tttcaaatag
    10561 cttacaacta atataaataa agataaatat cgtataaaag caactaattt ttctctgttc
    10621 attaaaggca ctcctccaaa aaaataaact tttgctatga aaactagaat aatatcataa
    10681 aagaataaag tcaatagaag tatttattaa tattgatgga aataaaatca atccaaaaac
    10741 ttgaatagta aaattgtata ctgacaataa tttaaaagtg aaaatttaat gtattggagt
    10801 gaataatgaa taataaagaa aaaggtgatt ttggagaaaa agtagcagtt aattatttgc
    10861 tatcaaaagg agcaaagata ctagaaaaaa attacagatt aaagataggg gaaatagata
    10921 taatagcaaa aatggaagat gaaattatat ttgtggaggt gaaatcaagg tctaacataa
    10981 agtttggcta cccttgtgaa tctgtaagct tcaaaaaaag aaaaaagata attggagttg
    11041 caagttatta tattataaaa aataacttaa ataacactcc cataagattt gatgttatag
    11101 aggtatattt attagaaaaa agaataaatc acataatgaa tgctttttaa aaaagataat
    11161 gtttttggaa aggattaaat atgttaagta ttattaattc aagcaactta gtaggaatcg
    11221 acagcttttt agttaaggtt gaagtagatg taagcaatgg aatacctagt tttaatattg
    11281 ttggtcttcc aggcaaagaa attaaagaag caagagaaag agtaaagtca gcaattctta
    11341 atagtggata taaatttcca agcacgagaa tagttgtaaa tttatcacca gcagatataa
    11401 aaaaagaagg agctttttta gatttatcta taagtatagg ccttttaaga gagttaataa
    11461 aaaaagatga aaattacata agagaaagta tgtttatagg agaattatca ttagatggga
    11521 aaataagaaa agtaagaggt atattgccca taattatggg tgcaaaaact cagaacataa
    11581 aacgtatttt tataccaatt gagaacataa aagaaagtct atttgtagat gaaattgata
    11641 taattcctat taaaagttta aaagaatgtg tcgatttttt aaacgaagag ataaaagtcg
    11701 ataaagtaag gataatgtct tttttggatg ataagtcaag aaaagagaac gaagaattag
    11761 aaaaagataa tagttatata gattgcaaat atactaagat taataatgaa gaaagtaaat
    11821 atgatgaaga ctttaaagat gtaaaaggaa attattttgt aaagaggagt gcagaaattg
    11881 ctgctgctgg aaatcataat atgtttatga ttggacctcc aggctcagga aaaactatga
    11941 ttgcaaaaag agtaaggaca attttaccag atataagtgt agaagaaatg atagaagtaa
    12001 gtaaggtcta tagtatattg ggtatgataa atgaaactaa aggaataatt gataaaagac
    12061 cttttagagc acctcatcat acaactacaa agcaatcttt aattggagga ggaatggatg
    12121 caagacctgg agaaattgct ttagcacata gaggtatctt atttttagat gagatagccg
    12181 aatttgatag aaaaatactt gagactttaa gacaacctat agaagatgga tatgtaaata
    12241 tatccagagt aaagtacagt gcaaaatatc cttgtagagt actgttagtt gcagctatga
    12301 atccatgtcc atgtggttat tatatgtcag agacagagtg tagatgtaga agtaacgaaa
    12361 ttgatagata cataaataaa atatcaggtc cattgttaga taggtttgat atttttgtag
    12421 aagttaattc tataaaatat tcagatttta attctttaaa acaagaagaa agctctcaaa
    12481 aaataaagag aagagtagaa aatgctagaa aaatacagat aaatagattt aagaaagata
    12541 atataaaaaa taatagtgaa attaaagctt acaatttatt taaatattgt aaactggaaa
    12601 aagaagcttc aaaaacggct gagatgatat ttagtaaata caacctaagc agtagaagtt
    12661 atacaaaact tttaaaaatg gcaagaacaa tagcagattt agaagaaaga gatttgataa
    12721 attcacagtg tattatagaa gctttttcat ttagaaaggc ttattatagt tattttaaat
    12781 agttttttga ggtggatttt atggaaaaaa gagatactta tttatggtta aaatcaattg
    12841 gtggaataac aacaaaaaca attgaaataa tagaaaatga aatagtaaat attgaagata
    12901 tatttgattt ttctgaaaaa gaaatatata atttaaaaaa tataagcttg aatattagaa
    12961 aaaatatagt aaaatataga ggtcacgctt atttagaaaa tataaaagaa ctactttaca
    13021 aaaaagcgat taaatatatt tgtaaatatg ataaagaata tcctgaaaat ttaaagaata
    13081 tatacaacgc tccaaagtta ttattctaca aaggtgacat aggcttagtt aataataatt
    13141 ttaatatagc tatagtaggt tcaagaaaac ctacagccta tggaattaat tgtgcaaaaa
    13201 caataagttg tcaactatcc caatatggag ttaatatagt aagtggatta gctataggaa
    13261 tagatgcata ctcgcacata ggttgtatga gtggaaaatc taaaactata gcagtacttg
    13321 gttcaggagt agacaatcct cttccaaaac aaaatttaca tttatcaaat aaaatattag
    13381 aaaatggggg attattatta tcagagtata atattaactc gacagtagcc ccgtaccatt
    13441 tttctaatag aaatagaatt atcagtggtt taagtgatgg agtagttgtt gtagaagcag
    13501 caataaaaag tggtgcacta atcacagtag attttgctct tgaacatgga aaaaatgttt
    13561 ttgcaatacc tggtaatata aattctcaaa tgagtagagg ttgtcataaa attataaaag
    13621 aaggtgcaaa attaattgaa aatatagatg atattttaaa tgaatataac atatttaata
    13681 ttattgataa aaaaataaat caaaaatatg ataatataag tctaaatgcc aagtctaagc
    13741 aaataattga agctataaaa agagaaggaa acttgcatat agatagtatt tgtgattata
    13801 ctggtataga aataaagtat gtaaattcaa taatcaatga attagtacta aatgagttag
    13861 tagtagaaat gaataataaa acgtacagtt taaatgtata aattaagatt aggtagtggg
    13921 ggtgtatggt tttatggcca aaacattagt catcgtagaa tcgcctgcaa aagctaaaac
    13981 tatagaaaaa tttttaggga aaagtcatta cacagttaaa gcatcagttg gtcatgtcag
    14041 agatttacct aaaagtaaat taggtgtaga tatagaaaat aattttgaac ctcaatatat
    14101 aaatataaga ggaaaaggcg atgtaataaa agaattaaaa aaagaagcta aaaaatctaa
    14161 acaagtatat ctagcaactg accctgatag agaaggtgaa gctatatcat ggcatttagc
    14221 tcatatacta aatttagatg aatctgagga ttgtagaata gagtttaatg agataactaa
    14281 ggatgcaatt aaaaaagcaa ttaaacatcc tagaaatatt gatataaatt tggttgatgc
    14341 acaacaggca agaagagtgc tagacagact tttaggttat caaataagtc ctatattatg
    14401 gcaaaaggtt agaaaaggtc ttagtgcagg tagagtgcaa tctgttacaa caaagttaat
    14461 ttgtgacaga gaaaaagaaa taaaggcatt tattccaaaa gaatattgga caatagatgt
    14521 tgaggctaag acagtaaaag acaaagatat aactttgaaa ttttatggta aaaatgatga
    14581 aaaaattgaa ttagaaaatg aagaagctgt aaatgaaata ctaaaagaaa tggaaggtaa
    14641 agatttaaag gttgagaaga tagaatctaa atcaagacgt aaatcagctc caaaaccatt
    14701 tacaacaagt atgcttcaac aagaaggagc aaataagtta ttttttacta ctaaaaaaac
    14761 aatgatgata gcacaagaat tatatgaagg tatcgacata gaaggtgaag gtactgttgg
    14821 tcttatatca tatataagaa ctgactctaa aagaatatct gatgaagcaa aagaaaaagc
    14881 taagggctat atcgtaaaca atttaggaga aaactactat aaaaacactg gtgataaaaa
    14941 agaaaaaaag gatactaaaa aggttcaaga tgcccatgag gcaataagac caacctcagt
    15001 tgatagaact cctgagagta taaaagcctc attgagcaaa gaccagtaca agttatacaa
    15061 tttaatttgg agaaggtttg tagctagtca aatggaagat tcagtgtttg atatactaaa
    15121 tgtagaatgt aaaataggcg atattgtatt taaggcaact ggttcaaaaa tgaaatttga
    15181 tggttatacc aaggtatata atttttcaga aagagaagac aaaattttac caagtataga
    15241 aaaaggagat atattaaata tagaaaatat attgccagac caacatttta cacaaccacc
    15301 agcaagatat acagaagcta gtttagtaaa aacactagaa gaactaggta taggtagacc
    15361 aagtacgtat gctccaacaa tagctactat actgaataga gagtatgttg aaaagcaagg
    15421 aacaagtcta tgtccaacag aacttggaat aatagttact gatattttgg aaaataattt
    15481 ccataaattt atagatgtag attttactgc tgatatggaa agtaaacttg atgttataga
    15541 agaaggcaat acagattgga aaaagattgt atcagaatca tatgcaccac ttaaagaggc
    15601 tattgaagaa gctcttgaaa atatagaaaa agtaaatatg gatgaagaaa ctgatgagat
    15661 ttgcgagaac tgtggttcta atatggttat caaatatggt agatttggaa agtttatggc
    15721 ttgtaaaaac tatcccgatt gtaaaacaac tagaccaatt atgaataaaa ttggtgttaa
    15781 atgtccaaaa tgtgaagaag gagatattat acttagaaaa tctaaaagag gtaaagcttt
    15841 ttatgggtgt tctaattatc caaactgtga ctttgtagct tggaataagc caacaggaga
    15901 gttttgtgag aagtgtggtt catatatggt tgaaaaagtg actaaatctg aaacaaaaac
    15961 agtgtgttct aataaagaat gtaataaaga gacaaaagag cataatgacg gaaaagagtg
    16021 aaaattgaaa aaaatcacat aattctcttg aaaaaggttc caatctatga taatctttca
    16081 agtgtaaaca actaatagaa aaataaattt tcattaaatg tgaaaataat attagaaaat
    16141 ataaaaggtt attaaaaggc ctaaatttca tgaggagatg attaaatggc aagtgaagtg
    16201 ttacaaaaaa caaggaaaat aaataaaaca ttacaaacaa gtggtggaag cagtgtctct
    16261 tttgatttac tggccggagc attgggcgac gttttaagtt ctaatgttta tgtagtaagt
    16321 gcaaaaggta aagtactagg tcttcattta aatgatgttc aagacagttc agttatagaa
    16381 gatgagtata ctaagcaaaa gaaattttca gatgaatata ctcaaaatgt gttaaaaatt
    16441 gatgaaacat tagaaaattt aaatggtgag aagatattag aaatctttcc tgaagaacat
    16501 ggaagattac aaaaatatac tacagtagtt ccaatattag gaagcggtca aagattagga
    16561 acattggtac tttcaagata ttcaaattca ttcaatgatg atgatttagt aatagctgaa
    16621 tacagtgcaa ctgttgttgg tcttgaaata ttaagagcaa taggtgaaga attagaagaa
    16681 gaaatgagaa agaaagctgt agttcaaatg gcaataggca ctctgtccta ctccgagctt
    16741 gaagcagttg aacatatttt tgctgaattg gatggaaaag aaggtctact tgtagcaagt
    16801 aagatagctg atagagttgg tataactagg tctgtaatag taaatgcact tagaaaattt
    16861 gagagtgcag gtgtgataga atcaagatca ttaggtatga aaggtactca tataagaata
    16921 cttaatgaca aacttacaga tgaattaaaa aaattaaaaa acaatcaata atctatattt
    16981 tataggttta gattagaaaa ggtatctatt tgaaatagat acctttttta gacgaattat
    17041 taaggtaatg ataagtatat taaaaaggag tgagaaaatg cctttagcag ataaaataag
    17101 accaaaaaca atgaatgatg taataggtca aagtcatata ataggtaatg gaaaaatatt
    17161 gtctaagata ttacaatcta attttttacc aaatatgata ttttttggtc ctcctggtgt
    17221 tggtaaaact acagtagcgg aaataatagc agaaagaagc aataaaagct tctataaaat
    17281 aaatgctact aattcatctt tagaagatat aaaaaaggtg atatcagagc ttggaagtat
    17341 aaataatgta aatggagtcc tattatatat agatgaaata caaagtttta ataaaaaaca
    17401 gcaacaatca atattagaat ttatggaaaa tgggagtata actttgattg ctagcactac
    17461 agaaaatcca tatcattatg tatataaagc tcttttaagt aggtctactg tatttgaatt
    17521 taaaccttta gaaaaacttg atgtagaaaa aggactgaaa agagctgttg aagtattaaa
    17581 tgaagatagc tatatggata ttgagtgtaa taatgatgct attgaagata tagcaattct
    17641 ttctgatgga gatatgagaa gagccttaaa tattttggaa gtggtagtct attcaactaa
    17701 accaaataag gataatataa cttatataga ttcagatgta ataagggcat ctacatttaa
    17761 taaaattata aactatgaca aaaatggtga tagtcattat gatattttaa gtgcatttca
    17821 aaaatctata agaggaagtg acccacaggc atctatacac tatctagcaa gacttataaa
    17881 aggtggggat ttgataagta tatgtaggag acttttagta atagctagtg aagatatagg
    17941 tttagcttat ccaaatgcta ttgtaattgt aaaggcatgt gtagactcag ctatgcaact
    18001 tggatttcca gaagcgaaaa taccattagc agaagctact attcttttgg ctacatctcc
    18061 aaagtctaat tctgcatgta tagcaataat gaaagctatg gatgaactgg ataaagagtt
    18121 tgttaaggat ataccaaata gtataaagga tgctcactat tctggttcta aagaaatagg
    18181 taggggttgt ggatacaaat atcctcataa ttttaaaaat cattatgtaa agcaacagta
    18241 tttaccagat agcataaaag atagtattta ttacatacca caagaaaata aaactgagaa
    18301 aaatataaaa aaatatttag aatatctaaa tagtgatttt tagactgaac tttatgtatc
    18361 gggggtagat attatgatta taaaacttaa ctcaacttat cacagtagag ttatgaaata
    18421 cttaaaaaaa gaacctgagt acaatttgtt tataataggg gatattgaaa gatatggata
    18481 tggaaataat tttttaaata tatgggcaga tgtgggtgaa catggtgaaa taaaggcaat
    18541 attacttaaa tattttgaat ttatgatgtt ttattctgat ggagagtatg atgttgaagg
    18601 tttttataat ctacttcgta atactaatta cgaagaaata tctgggaaaa tatgtgctgt
    18661 agatgcttta gcaaagagat taggacttaa taatttaaag gtagttgatt tttgcaaact
    18721 tcaaactaaa aagtttttga tagataataa ttgtaatgca aaggttaaga gaattaggct
    18781 tggaaatcta aaaaagacag tgaaacttta tgacttaata gatgaatttc acagtacaac
    18841 tttagagaat ttaaaaaatg gactaaggac aggtagagga tattgtatag agattaacaa
    18901 acaggtggtg tcaatggcaa agagtacttc agaaaatagg actcatgcaa tgataattgg
    18961 agtaggaaca catcctaaat atagagctaa aggacttgct acaaaatgcc taattaaact
    19021 atgttcagag ttactgagag aaaacaaaat tccttgtttg ttttatgata atgaagaggc
    19081 tggaaagata tataaaaaac taggatttga aaacattgga aaatggggaa tttattcaaa
    19141 ataaaaaatt aaaattaatc ttgacaaaat tagtagggta taataaaatt atcttgaaag
    19201 taattcctac taaaacagta tgaattagat ttctatatag aggtgataat atatgaagtt
    19261 gtctactaaa ggtagatatg gactaaaagc aatgtttgaa ttagcattaa atcaagacaa
    19321 tggaccagta tcattaaaat ttattgctaa gaagcaaaaa atatcagatc agtacttaga
    19381 acaaatattt tcatctttaa aaaaatcggg tctagtaaaa agtgtgagag gtgctcaagg
    19441 aggttatttg ctttcaaaga atgctgaaga cataacagta ggagatatac ttgtagtatt
    19501 agaaggacca gttgcattat ctgactgtgt actagatgaa gatgtatgtg aaaactcaaa
    19561 catgtgtgta acaaaaatag tttgggaaaa gatgaaaaag ggtatagaag atgttataga
    19621 ttcaattact cttaaagata tgataaatga ctataacaaa aataaattag aaaatgatat
    19681 aacaaatatt aaaaaataga tttggagatg aatgtaatgg aaaaaagaag attgtatatg
    19741 gattattctg caacaacacc tattaaaaaa gaagtattgg atgcaatgat gccataccta
    19801 acagattatt ttggtaatgc atctagtttt cacacattcg gaagagaagc aaaagatgct
    19861 ttggataaag caagagaaca agtagcagcc cttataaatg ctgaacctag tgaaatatat
    19921 tttacagcag gtggttcaga aagtgataac tggacactag agggtatagc ttatgctaat
    19981 aaaaacaaag gtaatcatat aataacttca aaaatagaac accatgcaat acttcataca
    20041 tgtgaatact tagcaaaaca tcatggattt gaaataactt atttagatgt tgatagcgaa
    20101 ggaaaagtag acttaaagca actagaagat tcaataaaag atactactat acttataagt
    20161 ataatgtttg caaataatga aataggaact atacagccta ttaaagaaat atccgaaata
    20221 gctaaaaaac ataagatatt attccacact gatgcagtac aagctacagg taatattcca
    20281 gtagatgtta aagaattagg aatagatttg atgagtatgt cttcacataa aatatatgga
    20341 ccaaaaggtg taggagcttt atacataaga aaaggtgtaa gacttcataa ctttgtccat
    20401 ggtggagcac aagaaaaaag caaaagagct ggtacagaaa atatacctgc aatagttgga
    20461 tatggaaaag cagcagaatt agctaaggaa aatatgcaaa atcatgtaga aactttaact
    20521 cgtcttagaa ataagttaat agatggtgtg ttagaaagaa taccttacac aagagtaaat
    20581 ggtagcttag aaaatagatt gccaggaaat gcaaactttg cattccaatt tatagaaggt
    20641 gaaggaatac ttttattatt agatatgtta ggaattgctg gttcaagtgg ttctgcatgt
    20701 acttctggtt cattagaccc ttcacatgta cttcttgcaa taggtttacc acatgaaata
    20761 gcacatggtt cattaagact tacagttgga gattttacaa cagatgatga tatagattat
    20821 atactagaga acttaccaaa agtaatagaa agacttagaa gcatgtcacc actttatgat
    20881 gatgcgaaga aacaaggttt agtaaaatag acataaagat aaagcataaa aaatagacat
    20941 aaattgagta ggaggaaaag ataatgcaat atagtgataa agttatggaa cattttatga
    21001 atccaagaaa tatgggagaa attgataatg caagtggtgt aggtgaagtt ggaaacccta
    21061 catgtggaga tataatgaag atatttttag acatagatgg agatgtaata aaggatgtta
    21121 agtttaaaac atttggctgt ggttcagcta tagcaagttc ttctatggca actgaaatga
    21181 taaaaggaaa aactataaaa gatgcattag aacttacaaa taaagctgtt gcagaagctt
    21241 tggatggttt accaccagta aagatgcatt gttcagtttt agctgaacaa gctgtaaaag
    21301 cagctcttat agattatgct caaaagaaca atatccatat accagaattg gatggatatg
    21361 ttatagatga tgctcatgac catgatgttg aagaagaaga ataaaaataa gtgattgtgt
    21421 tatgagaagt ttacaatgat taaaaagaag tactaatgat ataattagga cataaaaaat
    21481 agctgttttt aaaatagcta ttttttattg cctaaattaa gtattttaac ttgatttaga
    21541 ggttaattag ttaacaaaat aatccataag attcaaataa taaagatgat tattttttta
    21601 gaaaatagaa caagctatat tttaaataag tacaatactt gctctatatg gtataataat
    21661 aagtaatgca aaagatgagg tgaaatttgt ttatgaataa aaaagtaatg ataggtatga
    21721 gtggaggagt tgatagctct gtagctgcat atcttttaaa acaacaagga tatgatgtca
    21781 ttggtgttac tatgaagttg tggcaagatg atgatgttgt tgaaattgaa ggtggttgtt
    21841 gctctttatc tgctgttgaa gatgctagaa gggtagcaaa taaaataggt ataccatttt
    21901 atgttttaaa ttttagagaa gtgtttaaag aaaaagtaat agattatttt atagatgaat
    21961 atttggaagg aaaaactcct aatccctgta tagcttgtaa taaacatata aaatttgatg
    22021 atttttataa gaaggctaga caaataggtt gtgattatgt agctacaggt cactatgcaa
    22081 agatagaaaa ggatgaaagt acaggaagat atttgctaaa aaaatctgtt acagataaaa
    22141 aagaccaaac ttatgcactt tataatctta cacaagagca actagagcat actttattgc
    22201 caataggtga ctatgaaaaa gatagagtaa gagaaattgc taaggaaatg ggtatggcag
    22261 tacacaataa gcctgatagt caagaaattt gttttgttaa agataatgac tatgcaaatt
    22321 atgtaaaaaa acattctaaa aagcgtattg aagaaggttt ttttgtagat actaaaggca
    22381 atatacttgg aaaacataag ggtatattat attatactat aggccaaaga aaagggcttg
    22441 gaattacttt tggaaaacca atgtttgtaa tagacataaa tccaataaat aataccatag
    22501 ttcttggaga caatgaagat ttatttaaaa aggaacttat tgctaaagat gttaacttta
    22561 tatcaataga tacgttagaa gaacccttaa gagttcaagc caaaataaga tattcagcaa
    22621 aaccatcacc agctactatt catagagtag gagaagatac tattaaaata gtttttgatg
    22681 aagctcaaag agctattact aaaggtcaat ctgtagtaat gtatgatgga gatattgtag
    22741 taggtggagg tataatcgag aaaagtttat aaaaacatct aaaaaattaa aaaaataagc
    22801 aataaagtat attaagagta aataaagttt ataaaataaa tttattgtat atgaaaatat
    22861 agtattgatt aattttgtaa aatttagtaa tataattagt atattaatta aaaaacaaat
    22921 acagtgataa ggaatagtaa aatatttgat gtcttacaga gagagggaaa tgctggaagc
    22981 ccttagaata tgatatttga agcagccttt tagtagcaat cttgaacaat ttatctttta
    23041 taaagaagat ttaagtagag attgacggta gttacgttat agctaaggtt ttccgaagat
    23101 atcatacttt gtatgataat tagggtggta ccgcgattgt cctcgcccct ataaatttat
    23161 ttatagggac gaggtttttt atttaaacga aaaaataaaa tttattagga ggaacatgat
    23221 atggaaaaga tgggattaaa tgaaataaga agtaagtttt tagaattttt tgagtcaaaa
    23281 ggtcattatg tagcaaatag ttattcttta gtaccaaaca atgataagag tttgttactt
    23341 ataaactcag gtatggcacc tttgaaaaac tacttttcag gtgtagaagt acctccaagt
    23401 gtgagaatgt gtacatctca aaaatgtata agaacaggag atatagaaaa tgtaggtata
    23461 actgcaagac atgctacatt ctttgaaatg atgggtaatt tctcatttgg agattacttt
    23521 aaaagagagt caataaaatg gggatgggaa tttgttacag aatggctaaa tataccagaa
    23581 gataagatat gggtgactgt atatgaagaa gatgatgatt cttatgatat atgggcaaaa
    23641 gaaatgaatt tcccagaaga aagaatggtt agacttggaa aagatgataa tttctgggaa
    23701 ataggtacag gtccttgtgg tccttgttca gaaatatatt ttgatagagg agaagaatat
    23761 ggatgtgaca atccagactg taaaccaggc tgtgattgtg ataggtattt agaattttgg
    23821 aaccatgtat ttactcaatt tgatagagat gaagaaggaa attatagtct attagaaaac
    23881 aagaatatag atacaggtat gggtcttgaa agaatgggat gtattatgca aggcgtagac
    23941 actatctttg aagttgatac aattaaatct atactagaag cagttgagaa gttaacagga
    24001 gtaaaatatg gagagaatcc aaaaaatgat atatcaataa gaataataac tgaccatata
    24061 agagctgtaa cattcttagt tagtgatgga gtgcttccat caaatgaagg aagaggatat
    24121 gttcttagaa gactccttag acgtgctgct cgtcatggta agttattagg agtaaaagaa
    24181 ttatttttac agaaactaat agatgaagtt ataaaagtaa atgataaagc atatccagtt
    24241 ttagttgaaa aagaaagtta tattaaaaaa gtagttggaa tagaagaaga aaaattcaat
    24301 gaaactatag accaaggaac agaaatattg aactcttata tagaagtatt aaaaaatgaa
    24361 ggaaagactg tcctaagtgg tcaagaagct tttaaactat atgatactta tggcttccct
    24421 atagacttaa ctaaagaaat attagaagaa gaacatctat ctgtagatga agaagctttt
    24481 aatgaagaaa tggaaaagca aaaagaaaga gctagaaatg ctagaggaaa tatggatgga
    24541 gaaagttgga aggaagaccc tctatcaaaa ttagaatcta cagttgacag tacatttaat
    24601 gggtatagtg aaatttatgg tgaaggaact attgaagcta tagttaaaga tgatgagcta
    24661 gttcaaagtg cagaagaagg cgataaggta tctatagtac tagataacac tactttctat
    24721 cctgaaggtg gaggacaagt tggagattgt ggattgataa ctaatgaaaa cttagtttta
    24781 gaagtattaa atactaaaaa aggtgctaat aatagtataa aacatatagg tataataaaa
    24841 tcaggaagaa taagtaatgg ggacaaagtg aagacactcg tagatagaga aactagaatg
    24901 tcagctgcaa gaaatcacag tgctacacat ttacttcata aggcattaag agaagtatta
    24961 ggagaacatg ttaatcaagc tggttcttta gtaactccag aaagacttag atttgatatt
    25021 actcactttg aagcgatatc aaatgaagaa ttaaaagtaa tagaagaaaa agtaaataat
    25081 gttattttat catctttaga cataaaatgt gatattatga atataaagga agctaaagaa
    25141 aaaggagcta cagcactatt tggtgaaaaa tatggtgatg aggtaagagt agtttctatg
    25201 ggagattatt ctacagaact ttgtggagga actcacttga caaatacttc tcaagtagga
    25261 atgttcaaaa tattatctga aggtggagta gcagcaggtg taagaagaat agaagcaata
    25321 acaggaaaag ctgtttatga atacctaaaa gaaagagatg gaattatctc tgaagtttgt
    25381 gtaaacttaa aatctaaaga agataattta attcaaagaa taagttcttt attagaagaa
    25441 aataaaaact tatctaaaga attgcatgat atgaaagcta agatgagttt acaatcagtt
    25501 gattctattt ttgattctaa agttgaagta aatggagtta atttgataac taataaattt
    25561 gaaggtatgg atatggatac actaagagaa acagcagata atctaagaga taagcttggt
    25621 tctggtgtag tagtacttgc aaatgtagta gatgataaag ttaactttgt agttactgcc
    25681 actaaagatg tattagataa gggaatacat tcaggtaata ttgttagaga agttgcaaaa
    25741 atagctggag gaaaaggtgg aggaagacct aatatggcac aagcaggagc tagtgatgta
    25801 tctaaggttg accaagcttt aagctatgca agtgaggtta ttaagacaca agttaaataa
    25861 cattcactca aggaggtttt tagtttggaa aaagatttag actacactat gaaatttgaa
    25921 ggaataccag aagataggat gagtgtagga gatactattg attttgtata taaagcatta
    25981 gttgaaaaag gatataaccc tataaatcaa attatagggt atctcctttc tggtgattct
    26041 agctatataa ctagtcataa aaatgcaaga gctataatta aaaaatttga aagagatgag
    26101 atacttgaag aagtaatcac gcactatctg aatagaaagt aggtcaaata aatgagaaaa
    26161 aagattatgt cgttgtttgc aatagtcatt atgatttttg tatcaactgc tagctatggt
    26221 tttgctgaag aaaaaggcaa ggtcatattt attgatatga ataggaccaa tcttggaagt
    26281 atgatgaata ttccaatctt gaaaaatgag atagaaaaga gaggctatgt agctctcatg
    26341 aatataagag gggatcaagg tactgatgat agaaggtctt atgcaagtat gggtgcagga
    26401 acaagagcta gtgtaactac tgaagactat atcaattttc aaaaagtaga ccaagatact
    26461 gctaaagctt ttgaagtcgc aacaggtcaa aaagctaaag aaataaatga tttaggcatt
    26521 aatagatcta taaatgaaaa tcttgagtat ggagaatatg gagcaaattt agggtcatta
    26581 ggaaaaactt tatcagaaaa tggtttaaag acatctgtaa ttggaaatgc tgatataatt
    26641 gaaaataatc aattagttaa aaacagaaac ttatgtttag tagctatgga ccaatatgga
    26701 aggattgatt caggtaatat tgataatatt aataagaaag attctaaaat gccatttgga
    26761 atatctacag attatgataa attactagat gaaactaaaa aatcctataa aaatagtgat
    26821 gctatatttg tagaacttgg agatacatat agattagata tgtatagatt aaatctaaat
    26881 gataatactt atgatataat gaagaaaaat attgtaaaaa atataaataa atatcttgaa
    26941 caagtatttt ctatggttgg agaaaatgac actgtttata tagcaagtgc atttccaagt
    27001 gacctagatt ataagaataa gagaagactt tctccaataa taaaatttag tggagaaggg
    27061 aaaggtctac tggaatctgc cacaacaaga aaggctggaa ttgttgccaa tttagatgtt
    27121 ggagtagata tactaggtac atttggtctt gaaaataaag agatggtagg tagaagttat
    27181 actttagtaa ataaagagga caatattagc tatctaaaat cactttatga aaggatagtg
    27241 tctatatctt caataaggtc aactattata aatggctttg taggcgtaat atctgcttct
    27301 tgggtaattg ccatgtttgc gattttcttt agaaattata tgccacataa agagcgtgta
    27361 ttcaaagtac ttaaggagtt tataaaatta ggcataataa tgccactatc atttatgtta
    27421 gctcctttga tgaattttaa aactccaatt tcaatatctt tgggaatatt tgcaactacg
    27481 ctaatattat acttgttagg tagaaaatta tttaaggaca atgatataaa gcacatggga
    27541 ttttttgcaa cacttactat tttagtcata gttatagatt ctgtatttgg aacatactta
    27601 atgcaaaata acataatgag ttatgatgct gtcataggag ctaggtacta tggtgtagga
    27661 aatgaatatg aaggtgtaac tatagcaagt gcagtatttg gcttagcagt attattacat
    27721 tataagaagg tatctaaatt acttgttgta attttttcat taataatact tataactagt
    27781 gcatatcctt caatgggtgc aaatgttggt ggagctatat cagaatgtgt agcatatttg
    27841 ttgtttataa tgcttatata tgacattaaa atagatttta agaaagctgt attattagct
    27901 gtttcagctg tagttgtcgt ttttgcattt gcagctttag atatactttc aggtagtgaa
    27961 tctcatttag gtatgtttgt acagagaatt ttcctaaatg gaccaggaga gatattacaa
    28021 acatttggaa gaaaaattca aatgaatatg caactagcac agacaagtgt atgggtaaat
    28081 attttacttg taggaattgg agtaattgca gtgcttatat ttaaaccatc tagacacttt
    28141 agaaagataa tgaataattt tccaatcttg tttaaagggt ttattgcatc tatggttggt
    28201 tgtataatta ctcttttagt taatgattct ggaatagttg ctgcatctac agcatctata
    28261 tatatactta taccactaat aataataagt ataaatatga taatatttga aaaaaataac
    28321 taaaaaaatt tttactgttc atataggatt taaataaaaa atgcaatatg attattaatg
    28381 taaactggat gcttacataa aaaatcatat tgcaattttt atgattgatt atgtaaaatt
    28441 atatgaagca gtaagcctgt gaccttagtt atgataggtt cagaatatgt atttaatcta
    28501 tagaatataa atagataaag gaggaactat gttagatgga agaataatgg gtcttgatgt
    28561 tggtgataaa actattggag ttgctgtgag tgatttgatg ggattaactg cacaaggtgt
    28621 aaaaacaata aaaagagttg gcaagaaaaa agatattgaa gagctaaaag caataataaa
    28681 agaaaaacaa gtaaataaaa ttgtatcagg attaccaaaa aatatgaatg gaactttagg
    28741 tccacaagga gaaaaagtaa tcaagttttg tgaattggta aaagcagaaa caggtattga
    28801 tgtagagttt tgggatgaga ggctttctac agtagcggca gagaggtctt tattagaagc
    28861 agatgttagt agacaaaaaa gaaaaaaggt tatagatatg ttggcagcag taataatttt
    28921 gcaaggatat ttagatttta aaataaattc ataaaagaac tataaaattg aatacttatg
    28981 atatataata taaataataa aaataaaaat aaatttgagg tgaatgacat tatggaagaa
    29041 aatataataa atttaataga cgaaaatggc gttgaaagcc aatttgaaat aatattaaca
    29101 ttagaagcag aaggaaaaga gtatgcaata ttaatgcctt tagatgatga agaagctgaa
    29161 gaagctttaa tctttagaat tgatgaggat gaagaaggtg aaatcttaat acctttggaa
    29221 agtgatgaag agtatgaaac tgttgtagct gtgtatactg ctataatgga agaagaaggt
    29281 ttaaattacg acgaagatga atcaaatgga cttaactaga taagtaatta agtttgtata
    29341 taaaaatcag atatttatta tatttgcttt aattaaacct tattaattgt aaaagcattt
    29401 atagtatata tctgtttttt tgttttttat taaaaatacc aaaaaattta tgaattttgg
    29461 tgaataatat atcttttatg ggtatatatt tatattatga gaataaatta aatttattta
    29521 aatgtcttga caaaaaatga attatcaatt acaatattat ttaataaaga ttatcaattg
    29581 aaaatagtaa gggtgatgtt atggcaaata caatggattt attaaaagac aagttaaaag
    29641 aaactggttt taagattacg ccacaaagaa gagcaatagt tgaaatattg cttaaacatg
    29701 accattcaca tctaagtagt gaggaaatct atgatttagt tagggttgac tgtcctgaaa
    29761 taggcttagc tactgtatat agaacaatgc agctattgga tgaaatagga ttaatatcaa
    29821 aactaaactt agacgatgga tgtataagat atgagattag tctacataaa gaagactgtc
    29881 ataatcatca tcatcttatt tgtaaaaatt gtggaaagat aatggaagct aaagaagacc
    29941 ttttagacaa tatagaaaaa gagatacaat cattgtacaa atttaaaata cttgatcatg
    30001 atgttaaatt ttatggacta tgtgacgagt gtaatggagt aagcgattca gaagaataaa
    30061 cttctattgc ttaatgtcga tggaagaata gtatagaact tttatattct atgctattct
    30121 tccatttttt attataaacc atctataaaa tgcaaatata cagttttcaa gatgcttata
    30181 gttttaatat tgaaaatata attaatccta taagtacaaa aatgaatgat ttttctatga
    30241 aattactaaa tggtcctcca acagttaaaa aacctaaaga aattttcttt tcgcttagcg
    30301 gataaaaaat tggtattcct tgctttgtaa ataaatctcc taaaaacata tgacttgcat
    30361 aaccaatcgt accataaaaa gataaattat taatattagt gattaattct atctgtttta
    30421 gtaaaaaata tactattata gttgcaaata tgctatgaga aaaacttctg tgctttaacc
    30481 agggaaaaat tgacaacatt agacaaaaaa ttgtaaaata tatttcaact tctatgatgt
    30541 ataagcatat agctaatagt ataaatatta atgatagaaa aacttttctt agaaatgtgt
    30601 gggttagttt tgcttcaata attataattg caacaaatgt aattattgcg cttaaataaa
    30661 aattatcatt tatatttatt gaaataaaga aaataataat attaacagca tatataaaaa
    30721 ttctatatat gtatttggat acattgtttt ttagaatgaa atttgagacc atagaattag
    30781 atttatccaa atcgggtagt acagcaaaag tagctgaaac taaaatatca actaaagata
    30841 taggaatttt aaatattaaa gatgtttgga tagctgttaa gattcctatt gcacaatgag
    30901 ttttaccacg cataaatcct cctaaattat ccgatattaa atcatataat atttagagga
    30961 tatcaaaata aaataggttt gtcaaaataa tacgttaaat gtattttaaa tatagcttaa
    31021 aatatgatac gaattatggt acaataagaa taactggtag cgagtgcgtg atttgatatt
    31081 atttatgatt gtagaacgtg ttaaaaaatt aaatagacag aaggagatga tgcaattgtt
    31141 caaaaagaac accaacaaga taaaggtaat ggccttgggt ggacttaacg aagttggaaa
    31201 aaatatgact gttgttgagt ataaagatga aataattgtt atagatgctg gacttagttt
    31261 tccagaggat gaaatgttag gagtagatat agttatacca gatataactt atttagtaaa
    31321 aaatagggat aaaataaagg gtatatttat tacacatgga catgaagacc atataggagc
    31381 tcttccatat atattaaaga aaataaatgt acctgtatat ggggcaagac ttagtatagg
    31441 tcttatacaa gtaaaactta aagaacataa aatgaataat gttaagttaa atgttatagg
    31501 tcctagacaa gttataaagc ttgataatat ggaagtagag tttttgaaaa ataaccatag
    31561 tataccagat gcttactcta ttgcaataca cacagaccaa ggtataatat accacacagg
    31621 agattttaag attgacttga ctcctattga tggagatgtt atggatatgc atagaatctg
    31681 tgagttgagc aaaaaaggag ttcttttaat gctggcagat agtactaatg cagaaaaacc
    31741 aggatttact atgtctgaaa agactgttgg ggtaggtctt gacgaattat ttgcaaaagg
    31801 aaatggcaga agaattatag ttgctacctt tgcatccaac atacacagat tacaacaaat
    31861 aataaatact gctgaaaagt ttaatagaaa agttgctata tcaggtcgct caatggtcaa
    31921 tgtagttgga gttgcaaaag aattaggata cctagatatt tctgatgaca tgcttataga
    31981 tttaaatgat atatgtaagt atgaagatag tgaattagtg ataataacaa ctggttcaca
    32041 aggtgaacct atgtcagctc ttgctagaat ggctttttca gagcacaaaa aagtagaaat
    32101 aaagagtggc gatttagtta taatatctgc tcatccaata ccaggaaatg aaaaattaat
    32161 atcaagagta atcaatttct tatttgaaaa aggagcagaa gtagtataca gtgatatagc
    32221 tgatatacac gtttctggac atgcctgtca agaagaatta aaacttatac atgcattagt
    32281 tagaccaaag ttttttatgc cagctcatgg tgaatataga atgttaaaaa gacatgctga
    32341 aatagctgaa cagcttggta tggataaaga aaatattttt gtcatgcaaa caggagatgt
    32401 tttagaatta gataaaaatt ctgctaaggt agcaaaccgt atacaaacag gaaacatatt
    32461 agttgatggt ctaggagtag gcgatgtagg taatatagtt ttaagggata gaaagcattt
    32521 atcagaagat ggtcttatga tagttgtagt tactatttcc aaggatgagg gtaaggtctt
    32581 agcaggtcca gatataattt ccagaggatt cgtatatgta agagagtcag aagatttaat
    32641 ggatggagca aaggatataa ttaagaatgt tctaaatgaa tgtgaagaga aaaatattaa
    32701 agaatgggct tatttaaaga ataatattaa agaaaaccta aaagaatatt tatatcaaaa
    32761 aactaaacga aatccaatga tacttcctat cataatggaa gtataatata aaaaaactat
    32821 aaatttgaaa attagacctc ttgtaatttt taaagtaata tcaaaaatct aattgatatt
    32881 atcttaagaa ttacaagagg tctttttaat actcatttta aaaaatatat atattacata
    32941 aaataccaat tataacaatc ttttattagt aaaaactact tatatataaa ttttactgat
    33001 aggaggattc ttatggatga tgtttcaaga caaaatgcta taaaagcttt aaaacaaaca
    33061 aaaatggaaa tagcaggaga gtatggaatg aattatgaag atgcttttga aataatagaa
    33121 aatgcgtcta ataaaggtgt tttagaaggt tactttaaaa agcttgaaaa gaaaaaaaat
    33181 ttaggtcaag gtatatctag gcatttagaa taaaaaaagt taaatgtgag aaaataagtt
    33241 taaataaact ttaagaggtg acatcgatga aaaaattagc tagtactgct ttggctatat
    33301 taattgcgct tactccttta agcttttctt ttgcaaataa taaggaaaat gctgatgcca
    33361 accaactaaa tatatcttca aaatcagcaa ttttgatgga tgttggtagt ggacaaattt
    33421 tatatgaaaa ggatgctcat aaaaagcttc ctcctgctag tgtaactaag gtaatgacta
    33481 tgctacttat agtagaagct ttggattcag gcaagattaa gcttgatgat gaagttcaag
    33541 taagtgaaac tgcatctagt atgggtggta gtcaaatatt cctagagcca ggagaaactc
    33601 aaaaggttga tacattatta aaaggtatag ctgttgcttc tgcaaatgat gcttgtgttg
    33661 ctatggctga acacttagct ggaagtgttg aaggatttgt tgatagaatg aatgctaaag
    33721 caaaagagtt aaatatgaat gatactcatt ttgcaaatac aaatggactt ccagttgcaa
    33781 accactatac atctgctcat gatatagctt taatgtctag agaactatta aaacacgaaa
    33841 tgataagtaa atacttaact acatggatgg ataaggttgt agtagggaag aaacaagtta
    33901 cagtaggtct tgcaaatact aataaactta taaagcatta tcaaggagca actggtgtta
    33961 aaactggttt tactcaagaa gcaaaatact gtttatcagc atctgcaaag agaggtaata
    34021 ctcatctagt tgctgcaact ttaggagcag agacttctcc agaaagattt aatgatgcct
    34081 ctagcctttt aaactatgga tttgctaatt atgaaagtgt taagttatgt agtaaaggtg
    34141 ataatatagc aacacttaca ttggataagg ctgatgaaaa caaagttaaa ttggttgcta
    34201 aagaagattt aaatgctctt attaaaaaag gaagttctaa agaatttgag aagaaaattg
    34261 aaatagtaaa aaatcctaag atgccaatta aaaagggaac tgttttagga aaaataaaga
    34321 tatgtaaaga taaaaaagta ataggcgaag tggaattgat aaatactaag gatataaata
    34381 aggcaagcta tctacaaatg cttcaaagaa taattgataa tatgatataa ataattatca
    34441 gatgaaatat aattataata cacaaagata tgattataat acacataaaa aataccctta
    34501 tgtaattatt taccataggg gtatttttat ttaccatata gaagtatttt ataatcttat
    34561 gatttttata gaaatataga aaagtttatg tatcttaaaa tatcatttga tttaatatca
    34621 tatatagggt tgtttaacaa ttatctaagt aaaggcatac taccagtaag tttattcact
    34681 ttctttttat tcccataaat tgctatccca aaatactgta actcatcttc tggaacacta
    34741 gcaatctttt gcgtaaattc ttcataaaga ttgcaacttt gtgctacatc tgaaaaatct
    34801 acaacagtta aatcgttaaa ttccaaagta tataattttt tacgtaaatc ttttattatt
    34861 tctttgtttc cttttaaaat aggtacagga atgtcaataa ttcctaagtg gctattacct
    34921 gttttgtcaa ttacatctgg cccaacagtt tctggggcat gttttcctag tgtaattccc
    34981 attatagctg ctgtattgga tataattccc attggtaaat tttcgtctat taccatgaca
    35041 cattttgaat ttttattttc catttttatt tctccttttt accttattta aagttgtttg
    35101 aatcatcatt tataaatata ttttgatatt gctttggtgt aagaccaata aaattcttaa
    35161 aaaagtttgt aaagtgactt tggtctacaa atcctgtttg tatcgcagca tctataggtt
    35221 ctacgccttt ttctaaaagt tttttagctt tgtttacccg tatattttct aggtatctat
    35281 atggtgtaat accttttaat ttcgtaaaat tacgaagtag agagtactta ttcatacctg
    35341 ctatagtgct taattcgtca agtactatat gttcagcata attattttct agataatcac
    35401 atactgcttg aatttctata tttgtatttt ccaagttaga ttgcaaattt ggctctgtat
    35461 gttcttcaat taattgttca attaggaaga aaaaaagctc ttccttttta aaatccaatt
    35521 cttcttccat gattatatag tgtaattctt gtagtagagg tactagctca ctgcgaaata
    35581 taacaggttg attaaatttt ggtaaataat ttttacctgt aatttcaaag acagtttttt
    35641 tcattatttc tggcttaata ttaatacatc tgtaatcaag tactttatca tctatttgtt
    35701 cacaagtatg actatcaaaa gggttaaaaa gtagcaaatc tccagtactt gtggtatact
    35761 ctttattttt acaagataaa tatctttgac ctttttctat aaaaccaatt acataatgtt
    35821 catgaaaatg gtttgggaat ttttgcatta tgcctttaaa tgtatatgct tcaattttta
    35881 attccctatc aaagcatact gtgcgttctt cttgtctcac ttaggtaacc tcctttcatg
    35941 ttatacaaag tgtaacacat atttttttat acttcttgta taatattgac taagagacaa
    36001 taatgtcaat tcatgtcaat ataatattac acttacagta ggtgtaatta ttatattttc
    36061 acaatgaata tgatataata ataaaagtta taaaataaaa agcaaatttt aattttatgc
    36121 ctagaagtta aaattattat aatgtaaaat aattttgatt ataagctatt taattgttat
    36181 aataatatta aaaatttaat ttaggagatg tacattaatg ttaagtatga atataggaga
    36241 aatagtagca agtttagttg gtatagctat ggcaatatca atacatgagt ttggccatgc
    36301 ttattcagct cacttattgg gagatgatac agctaaagct tatggtagaa tgacattaaa
    36361 tcctgtaaga catgttgacc caataggtct tttggctatg tttatcctta agatagggtg
    36421 ggcaaagcca gtaccagtaa atccaaataa ctttaaaaac tataagatag gaaacctgat
    36481 agtttcactt gcaggcgttt tttgtaatgt tttgactgct atactgtgtg taattatcaa
    36541 taagtatgtg catatgtacg ctataaatac aatagctgga tatgtgcttt tatatagtat
    36601 gggatttgca gcttttaact tacttccgat acctccactt gatggatggg gagttatatc
    36661 tacatttgta ccatataaat ggaatgaata tttgtataaa tttgaaagta tgagttatat
    36721 aattttatta attgctttat ttactggtat atatcaaata atactatcac caatatatac
    36781 agtgttgcta aaaatagtat atttatttgt ttaatataat aaacagatta aagagggatt
    36841 gatatgaagt ataatataca attacaagtc tatgagggac cattagattt actttatgat
    36901 ttaataacaa agcataaaat agatataaag gatatatcta taatagatat aactaagcag
    36961 tatctaaatt atttgaaaat gctagataaa atggatttag agataactag tgaatttata
    37021 actatggcat caaaactttt agagataaag tctaaatatc tgctttataa gcaaaaagat
    37081 gaagaagaag acccaagaat agaacttatg gaaaagttag aagaatatag aaagtttaag
    37141 gtagcatcac aagatataaa agaaaatata acttatgtta atgagagatt ttatagaaat
    37201 aaagaagaga taattattga tgacaatgtg gatttagaag atatatcaat tgaagcaata
    37261 aaaaatatac ttccatacat atttaaagtt aaaacatcac agatagaaaa tgctaatgat
    37321 gagaaactag ataaaatagt aaggaagaaa ataatatctg tagaagaaaa aatattatat
    37381 ataagagata ttataaaaga gaagattgaa gttactttta caaatattat aaaatcatat
    37441 gaaaatgatg aaataatagc tactttttta tctatattag agcttataaa agaaaaagaa
    37501 atagtcgtag tacaagatat attttttgat gatattctaa taagaaaaag ttcggagtgt
    37561 taaaatgaaa agagaagata taaagtatat tatagaatct gttatgtttg catatgggga
    37621 accaataagt ataaaagaat taaactatat aataaataaa gaactttcat caaaagaaat
    37681 agagattatg ttaaatttac ttattgagga gtacagagaa caaaatagag gtattcaaat
    37741 aatcaagtta gagaataagt accaaatgtg tacaaataaa gactatgcag aatatataaa
    37801 gaagattatt gaaccaaaga aaaagaaaag tttgagccaa gctacattag aaactcttac
    37861 tataattgcc tacaaacaac caataacaaa ggtagaaata gaggatataa gaggagtaaa
    37921 atgtgataag gtattacaaa ctttgtttga aaatgaactt ataagagaag ctggtagatt
    37981 gaataagata gggaaaccaa taatttataa aacaacagat gaatttttaa agttgttgaa
    38041 tatagaaagt cttgaagaat tgccacctat agaaaattat caagaagtgg taacaaatga
    38101 ataaaaatat aaaatcacaa taatttagta tgtaatttta aattttaaaa gatttaaaat
    38161 gctctaagtt gttgtgtttt tttgtataaa tataaaatta taattctctt aaaataaata
    38221 tggataatta agtataaata gtaatttttt gatgataata taaacatgga gcttaatgaa
    38281 ttatttaatt ttaagtattt aataatagct gtaattttta ttataagtgt aactatgttg
    38341 attttaatat ctcatataaa catcttaata atagctgata taaaaaacaa agatatttgt
    38401 ttaaagctta atataaaata catgtttaat ttaataaata taaatagaca actttatcca
    38461 gctgaaaata gtaaaaataa tgataaaaaa gaggggatga agaataatat agattcaagt
    38521 atattattag ctgatgacct tttgagcatt tatagattat taaaaaagat aaaaatacat
    38581 gaactttatt caaatattaa ttttggaact ggaaatattg gcttaacatc ttctgtatat
    38641 gtattgataa atactttgta tggaaattta tttaatatga ttgatgcaga aaaaatgtat
    38701 ttaaatgtaa atccagattt tacaaaagat tatgttttag gaaatataag gatacatata
    38761 aggccaagaa taaaagcttt atttaatatt ataataatga ttaataaaat tatgaataaa
    38821 aataaaggaa ataaggaagg tgatagtaat gagagcaaca ggttcgatac agagtcttat
    38881 ggaaacaact cttgaaacaa ttaaaggttc tatagatgca aatactatta taggagaccc
    38941 tataaaaaca gatactacag tggttgtacc tatatcaaag gttacaattg gctttggtat
    39001 aggaggagga gaatactcaa aaggatatga tgataaagat agggaaattg aattaaaaaa
    39061 tgaaaaatca gatacgaatt ttgctggagg tagcgcaggg gctatatctg tacaaccagt
    39121 agcatttgta gtagttgaaa gtggagagac tagaataatg agtttagata gtaatatcaa
    39181 tctagtggat aatatattat ctataactcc tagagtattg gagaaaattc aaaatatatc
    39241 acaaagtaat aagaatcaag ataaaaacaa tatgtaagaa taaaatattt ttaaatatgt
    39301 atatagtttt aagtaaagta gtggggttaa tataaatccc actattttgt tgtgtacttt
    39361 aaacatttat atctaataag attttagttt aaaacaattt aaatagataa taaagttgat
    39421 atatagtata attataaaaa gaaaagaagt attatattat agatatataa acgcatttga
    39481 gatataagag ggagttataa atcattagtt ttgaggtgaa tgttatgagc gataaagaat
    39541 tatctatttt gttgttagaa agtatgaata attttcataa tttaataaag attattaata
    39601 acgaaagata taaaaaagat aaggttctta cagaaagaca gttctttgcc ttagtaaaaa
    39661 taagaaaaca tgataaaata gagcttaaaa atctaagtag agatttgcat gtatctactt
    39721 ctagtctgtg tatactactt aataaattgg ttgagcaaga gtatgtatat agggaagaag
    39781 atagtagaga tagacgaaat actttttatg gaataactaa aaatggagaa aagatattgg
    39841 ataatgaaat actaaagttt gtatctataa taagtgataa aatggattgc ctagatatag
    39901 ataataaaga taaattattt acttctttgg aagagtctaa aaatataata gaacaattat
    39961 tttaaaaagg agaatttatt atgaatataa agtattctaa agagatatta aaaagtttag
    40021 aaaatgctat aacagtagta gctctatttg agggagaaga tgtttttacg acatttgata
    40081 aaataaatat gataagcaga aattttaatt ctaaagaaaa tagtatagat actgtaacat
    40141 tggttgaaaa taacaatttg gtaaatgttt gtcttgttgg ttttggtaag agagagttat
    40201 tgaatagaga aaaaattaga atcataggtg ggaatttgtg taaaaaatta aaaaatatat
    40261 tgaaaaatga agcatataag agtagtgatg ttaatgtact gaatcttaat ttaaatagtg
    40321 atgaaatagg ttgttttgta gaagggatat tacttggaaa ttataagttt gataagtata
    40381 agacaaaaag taaggatttt gaaagaaaag aagttgatac tataactata tttactgaaa
    40441 aagaagttga gtgtcaaata gaaaaggcta aaatattagc taattcaact ataatagcta
    40501 gaaatctagt taatgaacca tcaaacgtaa tatatccaaa aacattagca gtagaaacag
    40561 ttaaacttgg tgcagagttt gggtttaatg ttgatgttta tgaagaagaa aaaataaagg
    40621 cattgggaat ggatgctttt ttcgctgttt caagaggttc aattaataaa ccaagattca
    40681 tagtaatgag atactttgga gataaagaaa gtacagatat attaggtcta gtaggtaaag
    40741 gattgactta tgatactggt ggatattctt taaaatcaaa tgcttctatg ctagatatga
    40801 agacagatat ggctggtgct gcgagtgtta taggtgctat gtgtgctata tctcaaagta
    40861 aattaaagaa aaatgttata gcagtagtgg cagcatgtga gaatgcttta tcaggaggtt
    40921 catacaaacc tggagatata attagttcta tggcaaagaa aactattgaa gttttaaata
    40981 cagatgcaga aggtagactt acattagctg atgcaatata ctacattata aacaatgaaa
    41041 aagtaacaaa ggtggttgat gtagctacat taactggtgc tgctttaaca ttgttaggca
    41101 atattgcaac tcctatagta acaaataatg atgattttta ttgtgaatta gaaaaagctg
    41161 ccactttatc aggggaaagg gtatggaaga tgccaattta tgatgaattt aaagatatga
    41221 taaaaggaga agaagcagac cttaaaaaca ctggtggtaa aaatgctgga tgtataacag
    41281 caggagcttt tattggtgaa tttgttggga atactccttg gatacatatg gatatagcgg
    41341 ggacaagtac atcatcaaaa tcaattggat acaaagcaaa gggggctaca ggagaacctg
    41401 ttagaacatt gtactatttg gcagaaatct aaaaaacaat tataaaatat aatttataaa
    41461 gccacatgga tatttttgta atttaagatt atctatgtgg ctttattttt tatttaaata
    41521 aattatttac tctttttctt tttttcaagt ataaaagtat ctctattaaa taaaagagca
    41581 ggtatgtaca taatactagt aacaaaaata aacgtaaaaa tagcagttgt gctatgactt
    41641 aaaaaaccat aatagtacct agagttggta aatgtgttta gtaaaaatat gaatgaaaaa
    41701 taaataaaac atatagctaa gttatctcta agtgcatatc tgttaactct aaattttcta
    41761 acatcaacca tatatatatc tgcataaatt atcaagcact tagataagat aaagataaaa
    41821 tatattaagc taggaaattc atagcccaag tttttagaaa aaatgagttc tccaactgaa
    41881 caaactaaac tccaagaaaa aaatatatta aaaagatgat actgcttaaa aattagtatg
    41941 gctatacaca gatatataca aatataattg attccaattg gtaaagagtt tagagtacta
    42001 taattacctg aagaaataag taataattgc tctagagcca taattattac aagtaatgta
    42061 caaattatct tctcaactgt atagctataa ggtaaaatat ttttggttag ttttggacaa
    42121 tagtataaaa ataatccaaa tataaagaga cttacaaatt gttcactaga aaaaagaaaa
    42181 attttaaaca tataacattc tctcctataa taaatttaat atgtatctat ataaatatat
    42241 tcattatatc tcaatttaat atataaaaaa gataataata gttagatttt ttatatgaat
    42301 tttaataggt aaaatatcct attgttttgt agatatatcc taattatgtc aaaaaataaa
    42361 aaaaatttta tttattagag tttttggaaa taataataac agatattata attaattaac
    42421 agtttttgta agtatttgac aatagagagg gtgtaacaaa tgggaataat agagtcagca
    42481 tcaaaattgg ctgagatggt tcatttattg gctgttgaaa aggggataac tgatatagaa
    42541 gcatgggatg aagctgtgaa agaatacagc aaaatttatg aagaaagaag aaatgaatag
    42601 aatgataaaa aatgaaaact tgatgataaa aaataacttt atttaaagaa attcaatttt
    42661 tatagaagta ttaaaaataa tataaataaa aagatggtat ttcaaatgta agtaaaaaat
    42721 cattttggga taccatcctt attatttatt ttaataatat ataagtaata aatcttactt
    42781 atccatattt tttatgtaac ctcttttttc tagctttttt atatgctcct tacgtatttc
    42841 atcaagatta ataccatatt gttcttctag cttaaacatc atagtaacac atgtctgcgc
    42901 tacatccatt agttccttag cagttttctt tataatatca acttcatcta aatcattatt
    42961 ttctccactt agatttctga atttacctat acattcagct aattcacctt gttcttcacc
    43021 cattttgata aatgtagatt ctagtgttgg gtctaaatta ttaagctctg gtaaagatat
    43081 agtttttagt ttcataaaag ctcctttcaa gttattcgta tttatactaa aacatcataa
    43141 caaaaataat actaaaaaaa aactttaaat tcaacataaa aacttacata tataataaaa
    43201 atcgtgaaat aaatctatat ttgtcttaat acagcctcat ataaaacttc tccaataggt
    43261 ttatttatta caagagaagc tgacttatca tagactgtat ttgctttatt aataagagca
    43321 atataatcac ctttgtaata atctataaaa cttgctgctg ggtacacagc taatgatgta
    43381 cctcctataa tcaataaatc agcattactt atagcagaaa ttgttttagt aatgacatca
    43441 ctgtcaagag cttcctcata aagtactaca tctggtttta ctatagaacc acagttgtca
    43501 cagtaaggaa tattacctcc cagatttaac atagattcta agtcaaaaaa tttaccacat
    43561 ttagtacaat aatttctatg tacagaacca tgaagttcta gcacattttt acttccagcc
    43621 atttgatgaa gtccatcaat attttgagtt atgacagctt taagcttacc catttcttcg
    43681 agttttgcta aagctatatg agcattattg ggttttgcat taggatatat taatttatcc
    43741 ttataaaatt caaaaaattc ttctggatat ctaacaaaaa aagtatgtga aactaattgt
    43801 tcagcagtaa attgtttatt gagtttttgg ctaaataatc cagtagaact tctaaagtct
    43861 ggaatattag attcagttga aacacctgct ccaccaaaaa atacaatatt attgtgatta
    43921 gctattaagt cttttaagct atttgcatcc atagttacac ctccaaatta ttatatataa
    43981 attgtactac atattaggtc gtttatgttt tattaattta aataaatata tagtttaata
    44041 agttaaataa agggaatata aataaaatgt atacagagta taaatagaca atatttacta
    44101 aaataacaag ttgtcgtata attatattaa aattgtttta gtgtataaga agggcggggg
    44161 aagtacgtga agaaaaaagc agctttagca acattggcta tgttaccctt aggtgtggta
    44221 aatgcacatg ctgatggaga tataggtata gtgactataa attatttaaa tgtaagaaat
    44281 gaaccaactg ccgaaagtag catagccttt gttgctaaaa aagatgataa agttttgatt
    44341 aaagactctt ctaatggatg gtataaaata aaagctgaat ctggacaaga aggttgggct
    44401 tcatcaaaat atatagcaaa atcaaatagt gactctttaa gaacgtctac aaataaagaa
    44461 aaacaagtta tttcaaatag tttaaatatg agaaatggag caggtacaag ttacagagta
    44521 ataactgtac taaaaaaagg tcaaaaagta gaagtaatat cagagagtaa tggatggtct
    44581 aaaatcaaat atgatggaag actaggatat gtatctagct cttatttagg agacgtttca
    44641 aactcaacta ataaatcaaa aactaaacaa gtgaatacaa cttcactaaa tgtaaggagt
    44701 ggaccaaata caagttatgg tttgttaggc aagttgccaa aaggaagtaa agtagaagta
    44761 atatcagaaa gtaatggatg gtcaaaaata aagtataatg gaaaagatgc ctatgtatct
    44821 agtatgtact tatcggatgt aagtcaaagt aattcagaca attctagtca aagcaatgat
    44881 aaaaagaata ctgataaggt tgtaaataca gcttctttaa atgtaagaag tggaccaggt
    44941 tctacatata gtaagttggg aaaagtttat aaaggaagta aagtaactgt actatcagaa
    45001 agtagtggat gggctaagat taattttaac aataaagaag catttgtagt aggcaattat
    45061 ttatctactt cagcagatac ttcaaataat aactcaaata gtaactctga taacagttct
    45121 aatagtaatg gcaataattc ttcatcatca ggtcaagtaa atggtatgtc aggtataagt
    45181 ggggctaaaa ttgattataa atctttgagt tatactttag aatctcatat aagtaaacaa
    45241 gttgagaaag cagcatcagg aggaaatgtg atagctccaa gtaataggaa aagcactcca
    45301 agtcctgaat ttagtacttt ttcagctcaa agaacaagct catttgtaaa tgcaagttca
    45361 agtgatatag aatattattt aaatcctaaa aattttacaa atactactaa aggtatgatg
    45421 cagtttttaa agattaacag ttatagagat ggtatttcag aatcaagtct taactcgtat
    45481 cttaatggtt tatcttctag tgtatttaaa aaccagggag cagcctttat aaatgctgcc
    45541 aagaagtata atatagatgt tgtatatcta gtatctcatg ctatgtggga aactgcttat
    45601 ggtaagtcta cacttgccca aggtcaaaca ttaacatctt ataagggaca acctcttagt
    45661 aagccagtta aagtatacaa tttttttggt ataggagcaa tagataaaag cgctaatgtt
    45721 tcaggtgcag aagcagcgta ttccaatggc tggactagtg tagaagctac aatagatggc
    45781 tctgcaaagt ggatatcaca aaattacgta aatagttcta agtacaatca gaatactatc
    45841 tacaagatga agtggaatta tgattataca tggcatcagt atgcaactga tgtaaactgg
    45901 gctaatggaa tttctggaat tatggaaaat ttaattggtc tttatggagg aggaagtagt
    45961 ttggtttttg aagttcctca atataagtaa tacataaata aaaaatatag actatgggta
    46021 gttttcattt tatttaaatt atctatagtc tttttgtata taatttataa tctgtaaatt
    46081 taatgttaac aaaactttta tgttataata ttaattctaa gtaaatataa gtgagtaata
    46141 ggtagaaata gataaaaagt ggtaataata tatataaaga taattttgag aaaggaggat
    46201 atatatggaa agtattaagg aatatttgga taagttagaa attaataata gtggtcttgg
    46261 aaagcaactt aaagaagttt atataaatag agtagtttat tttaaggaag ataagatagt
    46321 ttatttttat ctaacttcta aagatattgt ttctcatgaa cttttagata aatttaaaga
    46381 agaattgatg tataaactcg attattttaa agatatgaga atgaagataa gatttactgg
    46441 tcttgaaaga aaatccaata aagatgttat aaaaaaatat tggaataata tattgtatat
    46501 attaaagtat ctttgtccat ctattgcagg gtggtataaa caagtagaat ttctttgttt
    46561 agaagaagaa ttaaaaataa aacttccaaa aggtatattt tatgagcgat taatgaaaaa
    46621 aaatgtaact tatgtactta aaaccgtgct tagcgaagag ttgggattag atttaaatat
    46681 aacaatagaa aaagctgttg atgaaaaggt aaataaagaa agactcataa gaatcaatga
    46741 tagagaaatg gaagaaaaaa ttagggcttt agaaattgga aaagttaata actgtgaaga
    46801 aaatgaagag gaaagctatg tcattaagtc tgatgtagat gaaaatttaa tctatggaga
    46861 taatgcaaat gctatgattg aaaatatagt tgaattaaat gcatcttctg gaacagttgc
    46921 agttgttgga gatatatttg atgttgacac taaagaactt aaaaacggaa aaatacttat
    46981 gatagcttca attacagatt atactagctc aataagctgt aaactttttt taacagatac
    47041 aaataaggat ggagtacttg aaaatgttaa aaaaggagca tacttaaaaa tcaagggtga
    47101 catagtttat gatacatatc aaagagaaat tagtatgatg attagtggga taagaaaaga
    47161 aactagaata gagagagaag ataaatcaga ggaaaaaaga gtagaactcc atgcacatac
    47221 acaaatgtct tctatggatg ctatttgttc tgttaaaaag cttgtagagc gtgcagccaa
    47281 atggggtcat tctgctattg ctataacaga ccatggtgtt gtacaaggat ttccagatgc
    47341 tatgaatgca ggtaagtcaa ataatataaa aatactttat ggagtagaag ggtacttggt
    47401 tgaagatgat tctctcatta tagaggatgc aaatgataaa gaactttcgc agacatttgt
    47461 tgtatttgac atagagacaa ctggtttttc taatacaaat gataaaataa ctgagattgg
    47521 tgctgtaaaa atagaaaact ttaagattgt agatagattt agtgagttaa taaatcctga
    47581 aaaagatatt tcttataaga tacaggaatt gacaggaata actaatgaat taattaaaga
    47641 caagccaacc attgaagaag ttcttcctaa gtttatggaa tttgttggag atagtgtatt
    47701 agtagcacat aatgcagagt ttgataccgg atttatatcg caaaaatgta gggaacaagg
    47761 cttgttatat aataacaaaa aagtagatac acttatgtta gcaagagtaa tgttgccaaa
    47821 cttaaaaaga catagattaa atgtcgttgc aaaagaactt ggtattcctc ttttaaatca
    47881 ccatagagca gtggatgatg ctgaggctac agcacttata tttaataagt ttttgcagat
    47941 gcttacagaa aaaggtgcaa aaactctaag tgatgtaaac aatatacttg gaaagattga
    48001 ttacacaaag cttagcacaa atcatataac cttgatagca aaaaattcta taggtataaa
    48061 aaatttatat aaaataattt cagatgcaca tgtaaatcat ttttttagag caccaagaat
    48121 ccttagaagt gtattaaatg aatataaaga aggattaata attggttcgg cttgtgaagc
    48181 tggggtggtt tttcaagctg taaagaaaaa cgtgtctgat gaggaaatga aaaaaataat
    48241 agatttatac gattatattg aagtaatgcc tatagataat aatagattta tgattgataa
    48301 aggagaagta aaggacgaag aagagttaag ggagttgaat aggaaactaa ttgatacagc
    48361 caaaaaattt gacaaaattc cagtagctac tggggatgtt cattttttag acaaacatga
    48421 agctgtctta agaaaagttc ttaaatattc tcaaggtttt aaagtagatg aagaagaaac
    48481 ttatttacat tttagaacaa cagatgaaat gttggaagaa tttagttatc ttggagaaga
    48541 attggcatat gaagttgtag ttgaaaatag taatctgatt gccgatatgg ttgaagatat
    48601 aaaacctata ccagatgata cttatcctcc aattatagag ggctcagatg tggagttaag
    48661 agaaatgtgt tacaaaaaag ccaaacgaat ctatggagac ccaataccag aaatagctca
    48721 aaaaagactg gatagagaat taaattcaat aataagcaat gggtatgcag ttatgtatat
    48781 tatagctcaa aaactggttg caaaatctct ttcagatgga tatttagttg gttcaagagg
    48841 ctcagttggc tcatcttttg cagctactat gagtgatata acagaagtta atcctcttcc
    48901 agcacattat atttgtgaaa acgaagactg taaatattca ttcttttatg aaataggtga
    48961 atggggctca ggtgttgatt taccagacaa ggattgtcca aagtgtggaa gaaaacttgc
    49021 taaaaacggt catgatattc catttgaggt tttcttaggt tttgaaggtg ataaagaacc
    49081 agatatagac ttaaatttct caggaaatta tcagccaaca attcataaat acacagaaga
    49141 actatttgga gaggggtatg tatatagggc tgggactata ggtactgtag cagaaaaaac
    49201 agcttttgga tacgcaagaa aatatgtgga agaaaataat ataagtgtac caaatgcaga
    49261 agtacttagg ctttcaaatg gatgtactgg agtaaaaaga acttcaggac aacatcctgg
    49321 tggagttatg gttataccag actataaaga tgtatacgat tttacaccta tacagtatcc
    49381 agcaaatgat acttcttgtg gtgttataac tactcacttt gattatcatt caataagtgg
    49441 tagaatactt aaacttgata tacttggaca cgacggtcct accattataa ggatgcttga
    49501 agatatgact ggaataaata taacagaaat tcctttagat gataaagaga ctatgtctct
    49561 atttacatct acagaagcat taggtgttac accagaagaa ataaactgtc ctataggttg
    49621 ccttgctgta ccagagtttg gaactaagtt tgtacgacaa atgttacttg acacaaaacc
    49681 tactacattt gcagaacttg tacgtatatc tggtctctct catgggacag atgtttgggt
    49741 aaataatgca caagacttag ttagagaaga tatagttgga ttaaaagatg ttatatctac
    49801 acgagatgac ataatgaact atttaatatt taaaggatta cctcccaaaa tgagctttac
    49861 aataatggag agtgtaagaa aaggtaaagg tttaaaacca gaacacattg aagaaatgaa
    49921 aaaaaataat gttccagaat ggtatatagg ctcatgtaaa aagattaagt acatgttccc
    49981 aaaagcacat gctgttgctt atgtaatgac atcatttagg attgcatatt gtaaagttca
    50041 ctatccagaa gcattttatg cgacttattt tacgacaaaa gttgaggatt ttgatgcaga
    50101 tttaattgtt aaaggattag atgctataaa atcaaaaata aatgaaattg agtcactggg
    50161 aaatgatgca accacaaaag aaaaaggtat gttgaccgtt ttagaagttg ctcttgaaat
    50221 gtatgctaga ggaataaaat tattaccagt tgatatatat aaatcagatg caactgagtt
    50281 tatagttgta ggagaaaaaa cattacttcc accaatggca gcaatacaag gtcttggagg
    50341 aaatgcggct ataaacatcc aaaatgaaag aaaaaatggt gaatttatat caaaagaaga
    50401 tttgagaaag agaacaaaaa tatcaaaaac ggtaatagaa actcttacta atcatggttc
    50461 acttgagaat atgagtgaga gaaatcaatt gtcattgttt taagttagcc caaaaagttg
    50521 caaataaaag aattttatga tatcatagta tagaaaatag tatactttgc agaaactaag
    50581 agtgagacag ctgttctcac tcttttattt taaatatatt attaaaaagc tggtttattt
    50641 ttattaaata tattttattt aagattatat aaactggtca tttacaattg aataggagga
    50701 actttaatga aaaaaaattt agaagctaca attgaggaga ttgtaactaa aataacggat
    50761 gaacatggat ttgaaatggt tgatgttgaa tatgtaaaag aagcaggaga atactactta
    50821 agagtataca tagataaaga agaaggaata tctttaaatg aatgtgaatt agttagtaga
    50881 gaattaagtc caatactaga tgaaaaagac cctataaaag aaaattactt tttagaggta
    50941 tcttctccag gacttgatag agcattaaaa aaagacagag attttgttag atatcaaggt
    51001 agagatgtag atttaaaatt atataaacca ttaaatggat gtaagcaatt tgaaggtgaa
    51061 cttgtaggat taacagaaga taataatata aaaatcattg caaatggtaa ggaaatggaa
    51121 tttaatagaa aagatgttgc tattgtcaga ttagcaataa agttttagtg gtatattaaa
    51181 tagggaggat ataaaaaatg aatcatgaat ttatggaagc attagatgaa ttagtagttg
    51241 acagaggtat agataaagaa atacttatag atactataga acaagctctt ttaactgcat
    51301 acaagaaaaa ctttggttca gcacaaaatg ttagagttga atttgataga gacaagggag
    51361 atataaaagt attttctcaa agagttgttg ttgatgaatc agatttatat gatactttct
    51421 tagaaataga gttagcagat gctagagaga taaaccctaa ttatgaatta ggtgatatta
    51481 tagaacatga agttacacct aaaaactttg gaagaattgc agctcaaaca gcaaagcaag
    51541 tagttgttca aagaataagg gaagctgaga gagaaatagt gtataatgaa tttatagaaa
    51601 aagaaaatga aatagttaca ggagaggttg ctagagcaaa taaaaatgtt gtttatgtaa
    51661 atcttggaag aatagaaggt ataatgactc aaagtgaaca aataccattt gagaattata
    51721 aagcaggtca aaaaataaaa ttctatatac ttgaagttaa aaagactaac aaaggacctc
    51781 aaatagttgt atcaagaagt catccgggtc tagtaaagag attgtttgaa gaagaagttc
    51841 ctgaaatata tgaaggaata gttcaaataa aatctgtagc aagagaagca gggtcaagaa
    51901 ctaaaatggc agtaagatct atagatgaaa aaatagaccc aattggagct tgtgttggac
    51961 caaaaggact tagagtaaaa aatatagtgg atgaacttgg cgatgagaaa atagatataa
    52021 taaaatatag tgaagaccca gcagagttta tatcagcagc acttagccca tcaaaggttg
    52081 ttagagtaga tatagatgaa gatgaaaagt ctgccttagt aatcgttcca gattatcagt
    52141 tatcgcttgc tataggtaaa gaaggtcaaa atgcaagact agcagcaaaa ttgactaact
    52201 ggaaaataga tattaagagc gaatctcaag cagaacaaga aatgttaaat cttgaaaatt
    52261 ccaaagaaat agaagctgag gatgttgaag ctgaatttat cgaccaagaa gagttagata
    52321 cttcagagga taattttagt gaagaagagt aaggagggat gattttgaaa aaagtaaaaa
    52381 aagtgcctca aagaaaatgc atagcatgtc aagatagaga ctctaaaaaa gagcttataa
    52441 gaatagttaa aaataaagaa ggaaaaatat ttttagaccc aacaggaaga gccaatggaa
    52501 gaggagcata tgtatgtaaa agctctgaat gtctaaaaaa agctataaag agtaaagcat
    52561 taaataaagc ttttaaaata gatgttcctg atgaagtcta tgataatcta cttatggagt
    52621 tagaagaata tgaaaaataa taaagaaaaa gtactttcgt tcttagggct cgcaactcgt
    52681 gcagggaaaa tagtgtctgg tgatgattca actttgcttg accttaaaaa aggaaaagta
    52741 aatttgattt taatcgcaga agatgcatca aataatacta aaaaactttt taaagataaa
    52801 tcaactttta gaaatattcc atatctattt ttttcaacaa aagaggaaat aggatttgca
    52861 ataggaaaat ctccaagagc agttgtagga ataaaagatg aaaatttttc taaaaagata
    52921 attgaactaa tagaaattta aaataaaata gggggtgatc ttgtgtcaaa aacaagagta
    52981 taccaaatag cagaagaatt aaatatatca aatgaagagc ttataaataa gttagctgaa
    53041 ttagatataa atgtaactga caaagattca gtattagaag gtgaagagtt agaattagca
    53101 cttgaaatgt taggtgaaga tttatctcaa gaaaatggaa atgttataga aatagatgga
    53161 aagttgacag tacaagtatt agcaacgaaa ttagataaat ctccatcaga aataattatg
    53221 aagcttatga aaatgggaac tatggcaaca ataaatcaag agataagttt tgagattgct
    53281 gctttggctg ccaaagacta tggatttgaa ttaacagtag ctgaaagtga tgatacagaa
    53341 gctttagaaa tagaagcttt aatggaaatt gaagaagata aagaagagga tttaaaacct
    53401 agaccaccag ttgttacagt tatgggacat gttgaccatg gtaagacatc tttactagat
    53461 gcaataagaa aaactgatgt gatttcaggt gaagctggag gaataactca gcatataggt
    53521 gcttcagaag ttaaaatcaa tggacacaaa atagtatttt tagatactcc aggacatgag
    53581 gctttcacat caatgagagc aagaggagca caagttacag atatagcaat attagtagtt
    53641 gcagcagatg atggtataat gcctcaaaca gttgaagcta taaaccatgc taaagcagca
    53701 ggtgtacctt taatagttgc tattaataaa atagataaac caggtgcaaa cccagataag
    53761 gttaaacagg aattagcaga ccaaggatta ttagttgaag actggggtgg agaagtaata
    53821 gcagttccag tatcagctaa gaaaaaagaa ggaatagata cacttttaga aatggtatta
    53881 ttggttgctg aaatggaaga gttaagagct aatccaaata aaagagcagt aggaactgtt
    53941 atagaagctg agcttgataa aggaagaggg ccagttgcaa cagtacttgt tcaaggtggt
    54001 actttaacag taggtgaccc aatcgttgca ggtgttgcat gtggtaaagt tagagcaatg
    54061 ataaatgcaa aaggtaagag agtaaaaaca gcaggaccat ctacagcagt cgagatatta
    54121 ggtctatcag aagttccaca aggaggagac caatttgtcg aagttccaac tgataagatt
    54181 gctagaagtg tagcagcaag aagacaacaa atagttagag atgaaatgtt aaaatcaact
    54241 caaagattat cactagatgc tctatttagt caaatgagtg aaggttctat aaaagacctt
    54301 aatatagtta taaaagcaga tgtacaaggt tcagtacagg cagttaaaca atctttagaa
    54361 aaattatcaa atgaagaagt tcaagttaaa gtaatacatg gtggtgttgg agctgtaaca
    54421 gaatcagaca tattacttgc agcagcttct aacgcaataa taataggatt caatgtaaga
    54481 ccagttccag gtgcagaatc tctaggagaa aaagaaaatg ttgatataag aacatatact
    54541 ataatataca aggcaataga agatatacaa gcggctatga ctggtatgtt agaccctgaa
    54601 tatgttgatg aagaaacagg aaaagctgaa ataagagaaa tatataaaat atctggtgtt
    54661 ggaacagtag ctggatgtta tgtgactaat ggtaagatat ttagaaattg taaagtaaga
    54721 ttagttagag atagcataat aatacatgaa ggtgagcttg cagcacttaa gagatttaaa
    54781 gatgatgtaa aagaagttaa ttctggatac gaatgtggta tgagttttgt aaattataac
    54841 gacataaaag aaggcgatat agtagaagct tatataacta aagaagtaga aagaaaatta
    54901 taaattcgta tcaaagaaaa tcagttagta aagaaggtcg atggtatggc atcatataat
    54961 agaacaagaa ggatagcaga agaaataaga aaagtcgtaa gtactatgct tataaatgga
    55021 gtaaaagacc ctagaataac atctatggtg agtgtaactg atgtagaagt tacaaatgac
    55081 ctaagatatg cttatgtata tgtaagtatt ctaggcggag atgaagaatc cacactaaca
    55141 ggtcttaaaa gtgctggagg atatataaga agagaagtag gaaaaaatat aaaacttaga
    55201 tatattcctg agatagtatt taaacttgat gattcaatag aaaaaggaat gtatatggat
    55261 agccttataa aaagagttaa tgaaaaaaat gctcaacaaa atgaggatga aaattatgat
    55321 gaataatatg gatagtatta taaactatat ttatgagggt gactatttta tagttacctc
    55381 tcatatcagt ccagatggag acaatattgg ttctacactt tcaatgtatt atacattgaa
    55441 gaatttagga aaaaatgtat attatgtact tgatgatgaa gctccattaa atttaaggtt
    55501 tttggttgaa ggtgtaaaaa tctataagtc taatgaattt aatatgaaga actattctct
    55561 aattgcactt gattgtggag ataagatgag aatatgtgtg agtgatgaaa tcaaaaataa
    55621 tgcatcaaaa ttaatctgta ttgaccatca tgctagtaat gattcatatg gagatttaaa
    55681 ttatgtagat attgatgcat cttctacatg tgaattagtt tataatttat tagttagatt
    55741 tcagcaaata aaagatatta atattataaa tgaagatata gcaacatgtt tatatacagg
    55801 tcttgtaact gatactggaa acttttcgta ttcaaatgta catgcaagta gctttgaaat
    55861 ggcaaaaaat ttacttgttt taggtgcaca aaaaaatact ataatacaaa atatatatca
    55921 aagcaattct tctggttatt acaaattatt aggagaagct ctaaagggtt tggagatatt
    55981 tgattaaaaa atagttacgc acactcgtga ctttagtcat gagttagtag ctaaaatagt
    56041 cagcatatag ggaaacttat atgtagagat aggataaaac ctatccaata ctacttgaat
    56101 tgctggaaac ccctaaagct aaccaaacta aaacataagg atgaaataaa cctaagtgtg
    56161 aaagttacga aagtagaaaa aattggttag atggtataag gttaaaccct aagtacttta
    56221 aaatgggcaa tcagcaggta a
//
LOCUS       DAFAZV010000026        53267 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFAZV010000026 DAFAZV010000000
VERSION     DAFAZV010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 53267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53267
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.026"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..825
                     /locus_tag="KOU88_002209"
     CDS             <1..825
                     /locus_tag="KOU88_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBK3212085.1"
                     /translation="DKLKYFSYSQNSINTYKSCPLKFKYKYIDRINWKNDDVGSREYY
                     ETLKTGRDFHLICERYFSNIPLGIYFNEDDKNSKKFLKWMENIKKVVPIEKGKTYLPE
                     YEVRMTLNGDIIQAKYDLVVIGNNNIEIWDWKTESKKIDYKHVENRIQTIVYMFLAKE
                     VIPKVLKMDINVKDINMRYYQPEFDDLPITILYDEEKHEANRNKIQNYISMIKNTNYE
                     EHTYEDNLYNDIEKVYNKEERMCYRNKKHCKYCEFNKLCNGKEIDYSILEAEIYGT"
     gene            815..4282
                     /gene="addB"
                     /locus_tag="KOU88_002210"
     CDS             815..4282
                     /gene="addB"
                     /locus_tag="KOU88_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HBK3212086.1"
                     /translation="MGLRFVLGRSGSGKSTYILDEIKKEAQKNETTSIILLVPEQYTF
                     EAENRVSKLFLGKEKDKYLRVRVLSFKTLSNIVFSQVGGLTDVNINSSGKAMMVYRAI
                     EDVSEELNVFSKSKSQSGFVSSITDMISEMKQYNISPEMLENISGELDNETLSLKLKD
                     ISKIYNSFEGKLHENYVDAQDMLTSLASKIELSSYLDGACVYIDEFTGFTPNQYNVIK
                     SILNKSKSVNISLTVDDINYIGYSKSDMFSRTKFTYSKLTQLCNEEGIKILPQVNLNT
                     GVIKRFEKVKELQHLERFYNAYPYKIYSNPTENIKIKEFNNLYSEVEEIAREIVHLVR
                     DKNVRYRDITIATRDLNRYDFLVHSIFNEYNIPNFIDKKREAKSNPIVILIISALEMK
                     NRRYGYETMFRYLKSGLIGIDNDDINLLENYVLANGIKGKKWFDEKWDYRITQSLSGQ
                     ESEFELELKEKINEIKNRVLEPIVILQEKLRGKNRVKEICRYIYEFLLDINMPETIES
                     LIINFKDKGELDVANQYSQVWDIVVDILDQMVELMGDEIISLEKFIKLITLGFDEYEL
                     GLVPPSIDQVLVSSVDRMKNPDTKYLYLVGTTDGVFPLITKDSGILSDNDRESLGNKG
                     IEVDIDSKTRSFEEQFLVYKALTSTSKNLTITYPISDHEGKTLRPSIIISRLKKIFPN
                     IENKSYLVEENKSTDKDILKKITVKSPTFNELINVIKNYDSDGYNTEEINSIWLDIYR
                     YYLKDEIYSSITKKVIKGLSYTNQVHKIEEKKIRSLYKSNSLSISRLEKYAECPFAYF
                     IQYGLKAKKRKEYSFTPPDLGTFIHNILDRFSKELLQDNLTWRDIDEKYIELKIGIIV
                     DEIILKIPGYILNSSERYKYLAYRLKNMLTTAITIISQQIKQGSFEPIDYEVKFGNNG
                     KYPPIKMVLENGQEVSLIGQIDRVDEFEEGENKYIRIIDYKSGNKSISLTEIYYGLQL
                     QLLVYLDAILESAKDEDININPAAILYCRINNPIAKFNEDKDDEEIQEAILKELRMKG
                     LVVKDSHIVKEMDKSLIDGERKNSLVIPVGLTKDGNVGKSTSAISYEDFKLLRKYVRH
                     AIKDLCEEMLSGEIRIAPYKHKDGTSCDFCDYSAICQFDSTIKDNKYKNLNNKSNEEI
                     IKMMKGDVN"
     gene            4282..8109
                     /gene="addA"
                     /locus_tag="KOU88_002211"
     CDS             4282..8109
                     /gene="addA"
                     /locus_tag="KOU88_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBK3212087.1"
                     /translation="MSSPKWTKEQLEVIESRECNLLVAAAAGSGKTAVLVERIIQMIT
                     SRENPIDIDKLLVVTFTNAAASEMRERIGDAIGKALDENPENKHLQNQLVLLNKSSIT
                     TIHSFCLDVIKSNFHRINLDPNFRIGDQTECAILKQEAIEEVFEDLYEERDEGFLNLV
                     ESYAERGGDKEVQDIILGIYSFAMASPEPKKWLIDSAERFNIDENFDFSQSIWARAIL
                     DTVKIEINGLCLNMERALKEVESIEELETFAEKLSVEYKKIADISQACNKSWDEAYKK
                     MASMSFENYVKGVKRISKDAPSYIKESKEKAKTIRDKTKKSLESIVSATFNKDNDSIR
                     EEIKYLYNIVKPISSVVLRFEEEYSNKKREKGIIDFNDIEHFALNILTDVDEKGNIVP
                     SDIAVGYRNKFYEIFIDEYQDSNLVQEVLLKAVANTETPNRFMVGDVKQSIYRFRQAK
                     PELFLQKYNNYNDKKGSSHRKIMLYKNFRSREEVVDAVNYIFENIMNENIGEIEYTEK
                     ERLNLGANFNVDTDEKSIIGGATEIHLIQKDNKLDDDIINDKDDRINNKENEIEEEEK
                     LDNIQLEARMVGNIIKDLMKVNEDGKIQKVYDKGIDGYRPVEFRDIVILLRATSAWAP
                     VFADELMNMDIPTYADVGVGYFDTIEIKTILSLLQIIDNPMQDIPLISVLKSPIFGFT
                     PEDLIDIRVQSKDKIFYEVLKSTAEYDGFTDSQNENESEFIPSEECINKSKDFLIKLK
                     EFKEKSMYMSTDEFIWYLYTRTGYYAYVGALPGGSQRQANLKVLFERAKQFEETSLKG
                     IFNFVNFIEKLKKSSSDMGSAKTLGENANVVRIMSIHKSKGLEFPVVICSAMGKNFNT
                     QDFKKSILYHHNLGYGPQFVDYERRISFPSIAKEALKSKINIENLSEEMRVLYVAFTR
                     AKEKLIITGSTRNIQDSIKRWSNGIESLDTISQYEILKGKNFLDWIMPCVLRHRDLSN
                     LLEEVGLDAVFNVEHNSKWYGKLWNKNDILVEKKSDEEKESIEEILEKIDVDNPDSDY
                     YSEIEEKLNYIYPYEFSTRKPATISVTEIKKIQNNYEEELINTIFEQKVILKKPLFIQ
                     NEEEREKISGTERGTIVHLVMEVLDLKNVSSVNDIKSQIRGFVSKGIITEKQASIVNP
                     YKIYKFFASNIGKRMLNAEIINREKSIYAQVNMKDIYIYEKLINNDDKKLYDNESVML
                     RGIVDAYFEEDNQIVLVDYKTDFVNEENINQIIEKYKKQLDLYADIIETLTGKSVKEK
                     CIYLFGVDEAVCY"
     gene            8155..9366
                     /locus_tag="KOU88_002212"
     CDS             8155..9366
                     /locus_tag="KOU88_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBK3212088.1"
                     /translation="MRFIHTSDWHLGKSLEGHSRIEEQAKFCEEFIKIVESNEIDMVI
                     IAGDVYDTSNPPAQAEKLFYQTVSRLANNGQRCVLIISGNHDNPERLSAITPLAHEQG
                     ILIYGYPLSATIEAKYKGFEITYATQGCTKLNINGENIVVATLPYPSEKRLNEVFSSE
                     DEFEKQKNYSEKVGDIFRSLEENFRSDTINIAVSHIFVIGGESTESERPIQLGGSFLV
                     ERKDLPEKAQYTALGHLHKQQKASERLNAYYSGSPLQYSKDERAYTKGAYIVDIKAGE
                     KPIIEDVYFNNYKPIEVFKCNGIEEALDICEQNQDREIWSYFEINTDEIISQNEIKKM
                     KELLKDIIEIKPIITSCYEQESVDIKEKSMAELFREFYSFSKGVEPKGELMDLFLDII
                     SEEGESADETN"
     gene            9353..12880
                     /locus_tag="KOU88_002213"
     CDS             9353..12880
                     /locus_tag="KOU88_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3212089.1"
                     /translation="MRPIRLELTGLNSYIDKQVIDFEKLIERGLFGIFGTTGSGKSTI
                     LDAITIAMYGNISRNTKEYINSVCDKAIISYEFEIGSKNTRRRYIVDRTIARSKTGTK
                     TSNARLIEVLNDNTQNVLADKVVEVNEKVAQVVGLTANDFTRSVVLPQDKFNEFLRLS
                     RADRRDMLERIFNLEKYGRSLGEKVKKRKNIQLQNLKDLKSKLSQYDGITEEVYNNIN
                     QELIELKNLEKDKNNALDLAQKSYEESKTVYEEQLKLEKNELRKNELDLKNSEIKEKI
                     ALVENDSNAKKVDPYISSVQNLEKKIDEDSFAVSNLEKKLAILNQELEVTKNRYKKIN
                     KIKNEEIPKLSEEKIRLQQAIKLEEELVLLDRELKELKESGINLNKTKVELEKVKQVS
                     ESRKDAVTKSIKEVEGKIDKVNISAELKQKIFLAYEYEKDYNNVLEEKNQKLNKLEEI
                     LKETENINLKVRYIDKDKNDVNRNLENLSLHLDVLLKKCPGKSADLLLKSEYVTELRN
                     KANNTKENEIKKSSIQDELKIILESKFNTEREVNLLNEKLENNRKNRDDLEKELEELK
                     YLNLASELRRELKENMPCPVCGSKHHENHNITKYDENISFVKEKLEKLEKEKISIRNN
                     IEELNAKVSGYLSIEKMKTKELEDVKGKLGGIPSSQLLKKLDEEQRKLALLKSNIQEW
                     EKEKESTENKVTLAKEEKNKIEKEELKIRESLNNYKKLTRDLNIEIEGLENKCKKLKQ
                     EYLGLKTITKVSNLLSKVKEIRENEKELELLSTGHSNLLKNRDSLDIKIRENESKLHE
                     IEIELIKARELYVEKKLSRDNKYKEVISITKGDLAKNLLHNVEENICKILEQEESSKK
                     KLEEQRLEYEKNIAEKHNIDGRLKTAKEQYKDQKSTLNKLLAENKFESIYAVKRALLD
                     TDAVKKLIEEILEHEEEQKLLSFKIKSSKEKLNGRSIKKEYFEQLKDEIYNLKVEIGN
                     ISKDIGANQNQLITLKDSLDKINDFNKQLKVVEHNVDLLEELDKCVQGNKFVEYVSTN
                     QLKYIALEASKRLDGITKGRYALEIDSTLNFVMRDNFNGGERRSIDTLSGGETFLTSL
                     SLALALSSQIQLKGSAPLEFFFLDEGFGSLDSELLEIVIESLERLHSNNLSVGIISHV
                     EELKNRVPVKLLVSSSEAGIGSKVKIEYS"
     gene            13011..14264
                     /locus_tag="KOU88_002214"
     CDS             13011..14264
                     /locus_tag="KOU88_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBK3212090.1"
                     /translation="MLESPNNLIQIIFLIVLLIGSAFFSASETALMSLSKIRIRYMQD
                     EGVKGAKLVSSLIENPNKLLSSILVGNNVVNIAATSISTSLFIGLMGEKGVALATAVM
                     TVLVLIFGEITPKTIAANNSEKVSLLVSKPIKAIIFILRPIVWIFNIITNIIFKLFGI
                     TNKGAKSFITEEELKTMVNVSHEEGVLEMEEREIINNVFEFGDMQAKNAMVQRIDMVA
                     IDMEDSYDEIIQVFKTEKLSRMPVYEETIDDIVGILNIKDIIFLSDEEIESFDIKNYM
                     REPFFTYEFKKITQLLEEMKLEKSQMAIVVDEYGGTSGLLTIEDLVEVIVGDIEDEYD
                     EEEDEIQVIKEDEYIVDGSTKIGDVNELIGVNLESEEFDSIGGFIIGHLSRLPEENEV
                     IEVDNIRFCIESIEKNRIKKIRIYT"
     gene            14413..15465
                     /gene="ytvI"
                     /locus_tag="KOU88_002215"
     CDS             14413..15465
                     /gene="ytvI"
                     /locus_tag="KOU88_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBK3212091.1"
                     /translation="MSILENNFLYKLKNNTIFFCIYTLLFIFIYKAFPYIAPFFLGAI
                     IALMINPISQKLENKFRINKGISTLVLSFLAVAIVSTVTTIIVINSMKELMGFLNNIS
                     ANPEDISNTIMYFLNKINDFMKSFQEIANFDVEQLVNKFSGEVMQITKNLLTSILGLA
                     TSIPYIIIFIITLFIATYFIAKDLDKIENSFYNMFTVDVRKKVKNVKKEAGLSLVGYI
                     RAYTILMAITFFAIWGSFALFGLKYGLIVGFVGALMDLIPFLGIITIYLPVIVYYFLI
                     KNYFIAISMTVIFFVLSLIREILEPKLVSVNVGLNPLATLAAIFIGIQVKGIIGVIFC
                     LGLVCMHDILKKVDIF"
     gene            15556..16782
                     /gene="pepT"
                     /locus_tag="KOU88_002216"
     CDS             15556..16782
                     /gene="pepT"
                     /locus_tag="KOU88_002216"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBK3212092.1"
                     /translation="MKQKVVERFLKYVSFDTTSNSQCENCPSSEGQRVLAKYIVEELK
                     TMGVDDVSLDENSYIMATLKGNTDGVDTIGFISHLDTIEDVSGKDIKPRIIENYDGKD
                     IVLNEALNVITYVKDSPELEEFKGDDLIVTDGTTLLGSDDKAGIAEIVTAIEYLINHP
                     EIKHGDIKIGFTPDEEIGRGADLFDVEKFGAKYAYTLDGGIVGELECENFNAANATIT
                     IHGRNVHPGSAKNKMVNAIHIAAEISEMFPADERPETTEGYEGFWHLNSIGGNVENVS
                     MAYIIRDHCKEKFENRKSIMIENIEKINKKYDNRVELDLKDSYYNMKEKIEPVMFIVD
                     IAKEAMEELGIKPRLVPVRGGTDGARLSFNGLPCPNIFTGGLNFHGKNECIPVSSMEK
                     ATKLIVRIAEKYAERV"
     gene            16989..18041
                     /locus_tag="KOU88_002217"
     CDS             16989..18041
                     /locus_tag="KOU88_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp18"
                     /protein_id="HBK3212093.1"
                     /translation="MKIKSKKIIAFALSLGIMLPSCVYADTISKNQNAQVDMNNYLQG
                     RKSPKEEKLIGEDRFDTAIKISQSGWNNGSERVFLVNSNSLPDALASTPLASKLDAPI
                     LLTNKNSIPYNVIEEIKRLNPAEVILIGSEGAISSSVKESLEDMEVLVSRIGGADREE
                     TSLLLTRQLDDTGDLGVSKVAVVNGYNGLADATSISSPAASDNTAIIYTGKDSIRSEA
                     KNFITQNSTKTYIVGGEYSISKKLEGQLVNSERLAGTDRKDTNAKVLEKFYGKSSKVN
                     NMYFAKDGSGREADLVDGLAAGVLASKTKSPVVLASGSLSSAQKSFIKKVKADKFVQV
                     GGGKNSKPYAEALALQ"
     gene            complement(18459..19028)
                     /gene="yfcE"
                     /locus_tag="KOU88_002218"
     CDS             complement(18459..19028)
                     /gene="yfcE"
                     /locus_tag="KOU88_002218"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBK3212094.1"
                     /translation="MKIGIMSDTHGSLLYFEKALNVLSDCDVLLHGGDVLYHGPRNDI
                     PEGYNPKKFIETLNKLENIVIVKGNCDADVDQMVIEHPIQSPYVMSQFGEIRIILNHG
                     YIESEEEIIDKAKKMGGDILVLGHTHVKKLYMDDNLIVINPGSTSIPKDGSHSVAIID
                     IIKTDDEDELELDINLIDINTGNIININD"
     gene            complement(19053..19853)
                     /locus_tag="KOU88_002219"
     CDS             complement(19053..19853)
                     /locus_tag="KOU88_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+)/NADH kinase"
                     /protein_id="HBK3212095.1"
                     /translation="MKRIITINTNQLNKSLETKELLTRKLINAGFEVYSDIYPDTELI
                     ISIGGDGSFLRTVRDFDFPEIPIMGINTGHLGFFPDILPDKIDSFIEAYTKKDYIIQE
                     MSLLNAEVYTTTSGSNMLAVNEVVIRGDKSRTIHLNLSLDNKHIQNFSGDGMIISTST
                     GSTAYNYSAGGSIVDINLELMQITPLHPINTNAYRCFTSSIICSNESVIKIAPEYRFE
                     DSVLIVVDGVEHRFRQIENIKVSISDAKIKLLRMSNYEFWHRVSEKFL"
     gene            19988..20848
                     /locus_tag="KOU88_002220"
     CDS             19988..20848
                     /locus_tag="KOU88_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212096.1"
                     /translation="MFSIRNITKKLGKFKLNNINLELKEGDIVGIIGPNGSGKTTLIK
                     IIMGIIDADEGEIELCNETIENSPISFKNNIGFVYDSLQFYPHLKVKEFRKIVSLFYK
                     NFDRERFDEYLNKFDIEENMHIENLSKGQSEKLMLSSALSHNAKLLILDEPTAGIDPI
                     VRTEIMQYLQDFVKNGSSSVIISTHNTDNLIKIADYLVFINRGNQIFTVKKELIEQEY
                     KIIRANKAELEAIKESIVGVKEYKYYNEALVKVGDSLKVKSLLIEIDKHKVKNPTIEE
                     LMYYYVNEVR"
     gene            20848..21534
                     /locus_tag="KOU88_002221"
     CDS             20848..21534
                     /locus_tag="KOU88_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBK3212097.1"
                     /translation="MFNLIRKDLIIGISSDGIRNLKYILLFFVFYFFLNSISYYTVSI
                     VVSYLIFINTFECDYENDSRIFIRSMPVSIEDIVYSKYLLGVGLIISVTIIVSLLSKL
                     TSLVFFRNMVLNDVFFSVNIFLAILTILLPLIFKFGYGKMKVCGFIVSILIYFVYGSL
                     LKMISMIVYQVKHFNYSKVGGVYLSNYVTDIANTKYINLYSMTFLTIIIFIISMYFSI
                     KISKKNKFNY"
     gene            21586..22128
                     /locus_tag="KOU88_002222"
     CDS             21586..22128
                     /locus_tag="KOU88_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212098.1"
                     /translation="MKKFIKVSFFILGIFTLFIAINKLVYRDMVSVKDYEINHLEEIV
                     FDFDSRRSRDVGTIVRFKISNNSKYSYKLNSAKMKFENCVENKKGMNKCSAYVNVDLF
                     NEKNSITERTLKYGIKPNNQGYVDFVIPKGLNFDYRYFNESGMSVEYKGEYIVNIPMA
                     KGLYLVVGKNNDTWNANIME"
     gene            22207..22674
                     /locus_tag="KOU88_002223"
     CDS             22207..22674
                     /locus_tag="KOU88_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaK/EbsC family protein"
                     /protein_id="HBK3212099.1"
                     /translation="MSISNVREYFKQFGKEDSILEFEQSSATVELAAEAAGVIPARIA
                     KTLSFKIGDDAILIVTAGDAKIDNKKYKAEFNCKAKMLTPEEVLEFTGHAIGGVCPFG
                     LKNSIKVYLDDSMKRFDTVFPACGSSNSAIELTCEEMEKFSKCEKWVDVCKNW"
     gene            23383..24519
                     /locus_tag="KOU88_002224"
     CDS             23383..24519
                     /locus_tag="KOU88_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBK3212100.1"
                     /translation="MDLNSKKYQMLKELYVSFAENEVKPLATELDEEERFPYETVEKM
                     AKAGMMGIPYPKEYGGEGGDTVGYIMAVEELSRVCGTTGVILSAHTSLGSWPIYQYGN
                     EEQKQKFLRPLASGEKLGAFGLTEPNAGTDASGQQTTAVLDGDEYILNGSKIFITNAI
                     AGDIYVVMAMTDKSKGNKGISAFIVEKGTPGFSFGVKEKKMGIRGSATSELIFEDCRI
                     PKENLLGKEGQGFKIAMSTLDGGRIGIAAQALGLAQGALDETVKYVKERVQFGRPLSK
                     FQNTQFQLADMEVKVQAARHLVYQAAINKDLGKPYGVEAAMAKLFAAETAMEVTTKAV
                     QLHGGYGYTRDYPVERMMRDAKITEIYEGTSEVQRMVISGKLLK"
     gene            24578..25360
                     /locus_tag="KOU88_002225"
     CDS             24578..25360
                     /locus_tag="KOU88_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009524639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBK3212101.1"
                     /translation="MNIVVCIKQVPDTTEVKLDPNTGTLIRDGVPSIINPDDKAGLEE
                     AIKLKEEMGAHVTVITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWATSSALA
                     GALKNIDFDIIIAGRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFE
                     DCCHDLKVKMPCLITTLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLK
                     GSPTSVFKSFTKSVKPAGTIYNEDAKTSAGIIIDKLKEKYII"
     gene            25379..26389
                     /locus_tag="KOU88_002226"
     CDS             25379..26389
                     /locus_tag="KOU88_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBK3212102.1"
                     /translation="MGNVLVVIEQRENVIQTVSLELLGKATEIAKDYDTKVSALLLGS
                     KVEGLIDTLAHYGADEVIVVDDEALAVYTTEPYTKAAYEAIKAADPIVVLFGATSIGR
                     DLAPRVSARIHTGLTADCTGLAVAEDTKLLLMTRPAFGGNIMATIVCKDFRPQMSTVR
                     PGVMKKNEPDETKEAVINRFKVEFNDADKLVQVVQVIKEAKKQVKIEDAKILVSAGRG
                     MGGKENLDILYELAEIIGGEVSGSRATIDAGWLDKARQVGQTGKTVRPDLYIACGISG
                     AIQHIAGMEDAEFIVAINKNPEAPIFKYADVGIVGDVHKVLPELISQLSVAKEKGEVL
                     AN"
     gene            26408..27205
                     /locus_tag="KOU88_002227"
     CDS             26408..27205
                     /locus_tag="KOU88_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBK3212103.1"
                     /translation="MSTSDVKVYENVAVEVDGNICTVKMNRPKALNAINSKTLEELYE
                     VFVDINNDETIDVVILTGEGKAFVAGADIAYMKDLDAVAAKDFSILGAKAFGEIENSK
                     KVVIAAVNGFALGGGCELAMACDIRIASAKAKFGQPEVTLGITPGYGGTQRLTRLVGM
                     AKAKELIFTGQVIKADEAEKIGLVNRVVEPDILIEEVEKLAKIIAKNAQLAVRYSKEA
                     IQLGAQTDINTGIDIESNLFGLCFSTKDQKEGMSAFVEKREANFIKG"
     gene            27303..28148
                     /locus_tag="KOU88_002228"
     CDS             27303..28148
                     /locus_tag="KOU88_002228"
                     /EC_number="1.1.1.157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxybutyryl-CoA dehydrogenase"
                     /protein_id="HBK3212104.1"
                     /translation="MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLD
                     KNLTKLVTKGKMDEATKAEILSHVSSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLD
                     ELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPMMKLVEVISGQLTSKVT
                     FDTVFELSKSINKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLG
                     ANHPMGPLALGDLIGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRANQLGRKTKIGF
                     YDYNK"
     gene            28235..29410
                     /locus_tag="KOU88_002229"
     CDS             28235..29410
                     /locus_tag="KOU88_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000786547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBK3212105.1"
                     /translation="MREVVIASAARTAVGSFGGAFKSVSAVELGVTAAKEAIKRANIT
                     PDMIDESLLGGVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLI
                     ALGDADIMLVGGAENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGIT
                     AENIAEQWNITREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEY
                     IKPGTTMEKLAKLRPAFKKDGTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIV
                     SYGTAGVDPKIMGYGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDM
                     NKVNVNGGAIAIGHPIGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR"
     gene            29605..30507
                     /locus_tag="KOU88_002230"
     CDS             29605..30507
                     /locus_tag="KOU88_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK3212106.1"
                     /translation="MFKKENQRYNLISYTNEEEMTLKEVLLDKLNFSVRSLSKMKREK
                     SVLVNGVYKKPSLKVYSGDLIEVKIDEEKANFEPQDLNLQIIYDDFDIIMVNKPPFMV
                     VHPTKSHYDKTIANGISYYIDNQKENVKIRFVNRLDMNTSGLVIVAKNAYAHHTLSTA
                     MSENKVEKKYITVVDGIIKENEGTIDEPIYRPTEDSIKRIIDERGQSSVTHYKVIERL
                     ENATVLEVSLETGRTHQIRVHMAHIGHGIIGDELYGYVDEELINRQALHAYKLEFEQP
                     RTKEKLKFKADIPEDMKELISKLR"
     gene            30521..31525
                     /locus_tag="KOU88_002231"
     CDS             30521..31525
                     /locus_tag="KOU88_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBK3212107.1"
                     /translation="MIIHKFIIHVLDKNSDVPILNDFEGKVNQEVDGFFQKAIKRIAK
                     DEDLRKGVFKDYNDNLIKNCCEQIIYDESTFLKNSKEIASYLFDVMKINAALESCDLA
                     ICLYTIKDEKSVAILKLDYKKLYTHSIEFVDDKFNIQMVSNEIGIPETLRQKQGALIS
                     LSGINDEFHLRLLDKDAEKEGSESKFVTEFLNAKKIDDDKYKTKVFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLKEKHEVDINDFVDNSIKDDELKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRSIKTDNGFDIKGNLTDFEDPMKYTVKQNQDGTIDIIIKNVTFYEEK
                     "
     gene            complement(31669..31896)
                     /gene="acpP"
                     /locus_tag="KOU88_002232"
     CDS             complement(31669..31896)
                     /gene="acpP"
                     /locus_tag="KOU88_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBK3212108.1"
                     /translation="MFEKIKEIIAEQLGVDNLDEITMEASLMDDLEADSLDAVEIIMA
                     LEDEFGIEIPDEEAENFKCIGDICKYIEENK"
     gene            32068..32493
                     /locus_tag="KOU88_002233"
     CDS             32068..32493
                     /locus_tag="KOU88_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212109.1"
                     /translation="MKYVGLLLTSVGMFLLIAVNFYYNSITLDMQRIEDYVMETNLIL
                     EDVAEKESYVSNEKEDYISRLMHVKKGIENSKTSFLIERYKEYKIKSIESLIYTISEE
                     KKDYLDEVDRYNKLGEKEINKLINKNFLEVTYLSITTYI"
     gene            32541..32747
                     /locus_tag="KOU88_002234"
     CDS             32541..32747
                     /locus_tag="KOU88_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212110.1"
                     /translation="MTKLEDNMERFFGGCEGFFGNKMLIIIVIVFLLLCTDILEDLLC
                     DDNIWIWVILIVLLLFNFDDGCCC"
     gene            32929..33108
                     /locus_tag="KOU88_002235"
     CDS             32929..33108
                     /locus_tag="KOU88_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212111.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFGDSWAEFDIMAWIPF
                     LIVLLILCCCGGCLE"
     gene            33142..33342
                     /locus_tag="KOU88_002236"
     CDS             33142..33342
                     /locus_tag="KOU88_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212112.1"
                     /translation="MLDRFFGEEGCFGGGGWWIIVLFFLFLAFEDCWRDIDIMSWIPF
                     LILLLITCSCGGFFDGEVGCGC"
     gene            33595..34611
                     /gene="ccpA"
                     /locus_tag="KOU88_002237"
     CDS             33595..34611
                     /gene="ccpA"
                     /locus_tag="KOU88_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator CcpA"
                     /protein_id="HBK3212113.1"
                     /translation="MKGNITIKDVAKQAGVSISTVSRVINDSKPVTDEVKQKVLEVIK
                     ETGYIPNPLARSLVTKKSQLIGVIVPEVSDSFVNEVLNGIEEVAKMYDYDILLANTYS
                     DKEQELKSINLLRAKQVEGIVMISWIVEQEHINYIQNCGIPATYISKTARNYDIYTVS
                     TSNEEATFDMTEHLIKKGHEKIAFIMTSKDDTVLEMERLAGYEKALSNNNIELDKSLI
                     KYGGTDYESGYNSMKELLDDGIIPHAAFVTGDEAAIGAINAICDAGYKVPEDISVAGF
                     NDVKIARMYRPKLTTVYQPLYDMGAVAIRMVIKLINKELIENKKIELPYRIVDRESVT
                     ERKK"
     gene            complement(34734..35132)
                     /locus_tag="KOU88_002238"
     CDS             complement(34734..35132)
                     /locus_tag="KOU88_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212114.1"
                     /translation="MKKLDTESLEKMAKQKNIDKDKIEKMADSYKGKSENELMEELIK
                     IGKNLDGRDEVVSKFKAFLDENQRKKLDNIMEKISDAENQRDTKPAKTKKAKPTKGKS
                     NSPAPKNTPGSQQKKSKSLFKKTKKSNPHE"
     gene            35344..36249
                     /locus_tag="KOU88_002239"
     CDS             35344..36249
                     /locus_tag="KOU88_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212115.1"
                     /translation="MNNLLFLIGVIALSNGNISIFDDKNKSKGNNRVRKNKKNANDKL
                     SQSTHGNLRFDANDIKRGLRLMDLSEEDLEMGMEIITRTKKYMSRDERKILIKIESVL
                     DLVRGIKKLNNIDMVDTEDETDFFRKMDSDDKKNMMIKEIIDVFPEKRKNSVEKAIGM
                     KKKIDLFAELFLPDDFGEGGFSLSSLANINNLGSMNNLKLLGSLLRGDDSNNDDEDNN
                     DELNYEDEELDCEDKELDDDELTDEGEMEDNEDELVEDKNTGYENIENDEDIVYDEEL
                     YNINEQESEYNYNEKNTKTRAKKKR"
     gene            36364..36544
                     /gene="ssrS"
                     /locus_tag="KOU88_002240"
     ncRNA           36364..36544
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="KOU88_002240"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            36727..37944
                     /gene="cdeC"
                     /locus_tag="KOU88_002241"
     CDS             36727..37944
                     /gene="cdeC"
                     /locus_tag="KOU88_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exosporium morphogenetic protein CdeC"
                     /protein_id="HBK3212116.1"
                     /translation="MQDYKKNKRRMMNQPMSTMNEEEVYTDEINSEDMRGFKKSHHHN
                     GCNTDNKCECHDDCNPCNPCNPCKPNPCNPCKPNPCDDNCGCHDNCKCDCEPCEMDSD
                     ECFENKCGPECCNPISPRNFSVSNAVPFAIEANRIFDTMQFQTFTDATGPNGEPLTFE
                     TEVVEVFGSVPSAGQASVTIEKICLSNDGIVIDTGMTTLEDFDLDPLGDIVGRNCETT
                     FEFAVCGERNSECCRQGKGKSVAYKQRGLTVAVRNLVLELRGRCGCTEFVALAFPAVR
                     AGGGCKRRVDYVEFTFNTLSAPICLPADGRAVTLRQEYQTNLTVDCIGKSILKLECNE
                     CCEPFYELIIPNDIDLVLCLQETVSTLISEQIVVLASPNPIQPRLVDTFSKVCDFSQC
                     GPNHGSGKPSCHR"
     gene            complement(38044..39366)
                     /locus_tag="KOU88_002242"
     CDS             complement(38044..39366)
                     /locus_tag="KOU88_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK3212117.1"
                     /translation="MKVPYLVLSTVILFISNFIVRIFGFLYKIFLSRALGETGLGIYH
                     MIFNFLMICLAVTTTGIPTALSCLVAKRKALNDRHNTNALFISTLYISFFVALIISIV
                     ASFNSSFLSLKFLKDAKLNLFILAVCPAIVIITLSNVLRGYYYGIKNVKIPAIGQIIE
                     QIGKILFVFLLVMYINNKSMNCYIALLGISIGELSNIIFMLICLWRDSSFDNRYIISI
                     KDFYNSSMETLKMSIPITCNRMSNILLQSISSMMIPSRLALSGMTYQQSLSMYGIVSG
                     MVMPFIFLPFTVGSALIVNLIPTISQEMALRKRKSVIKKIKYSILLTLFVGILSSIFF
                     YFFGKDLCILVFKNTLAGEYLKAMFLVPLFMSLNQTLSGILHSIRKELASSINTITGM
                     LIQLIALYVFLPIPGLNIYAYIYTMTIVSIFTCLLHTIVLFKSLKSIR"
     gene            complement(39417..40211)
                     /locus_tag="KOU88_002243"
     CDS             complement(39417..40211)
                     /locus_tag="KOU88_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBK3212118.1"
                     /translation="MFYDYHMHSSFSTDGKSTMEEMVKKSIELGLEEICFTDHVDYDV
                     YADDSFSIVYEDYFKSLETLQSKYKDKISIKKGIEFGVQTQLMDTYKKEAHQYPLDFI
                     ICSIHAIDTMDLYLGNYFKDKTQHEVYENYYLYLYNIVKNYKDYSVLGHLDLIKRYAP
                     YDTILDDRLFSDIIEETLKQAIYDGKGIEINTSCYRYNLPDLTPSKYILQMYKDLGGE
                     IITTGSDSHHISQVACEFDYIYSLLKNMGFKYVSKFNKLKPEFIKL"
     gene            40321..41766
                     /locus_tag="KOU88_002244"
     CDS             40321..41766
                     /locus_tag="KOU88_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK3212119.1"
                     /translation="MEKYRIDLNEKKSTKYIQIFNHIKELIINKELVEHEKLPPIRKL
                     SNFLQVNNTTIVKVYELLENEGYVYKIIGSGTFVSSLNSYKSGIDNRKNKIIVQREDL
                     IHFDNGNPSNDMFPIDSFKNAVNMALSKDGSSIFEYDEGLGSEELREKMVEYLSDGNI
                     KTTKENIQIISGAQQGIDIVCKGLISYSDVVFMEEPSYNGAIEVFKSRGAKIISIPML
                     DDGIDIGILKLKLEKIKPRLIYIMPNFQNPTGISYSTYKKKKLIELAEEHDFYIIEDD
                     FISDFVFESKDNRTIRSYDDKNRVVYIKSFSKILMPGLRIGIVEMPNELLKKVLWAKY
                     SSDISTPGLIQKSMYYYMNNFDWKNYLSHIEKIYTDKYKLAKNLINDKLSGKLKVRKS
                     CGGINFFLELPRGYTSQAFTNFMLNKGVSMLPGTYFFDNLVDDRFFRINIARPSMEEL
                     EKGISIISDNIDEFFCEYKNKLDIKSNKLFY"
     gene            41795..42004
                     /locus_tag="KOU88_002245"
     CDS             41795..42004
                     /locus_tag="KOU88_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HBK3212120.1"
                     /translation="MFDKKKLDRINELAKKNKEGILSADEIKEREILRKEYLENFRAH
                     FRSRLDSVKVVSPEEYEQYMKNNKN"
     gene            42024..43418
                     /locus_tag="KOU88_002246"
     CDS             42024..43418
                     /locus_tag="KOU88_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBK3212121.1"
                     /translation="MNLKYEFKNAWDFERKENTIEQIMQYSSNYMEFLSKSKTERLSV
                     KEIIKLAKENNYISIDEAMEKGSISCGDKIYVINKEKAVALFVIGKNYIEKGMKIIGS
                     HIDSPRLDLKPNPLYQESNLGFFKTHYYGGIKKYQWTAIPLALHGIVILNDGTKVDIS
                     IGEEDSDPVFCVTDLLIHLAGDQMQKKLSEGISGEALNILIGNMPLEDEEKEPITANI
                     LKILNEKYNIVEEDLLSAEIEVVPAGKARDLGLDRSMVLGYGHDDRVCSYAAVKAILE
                     TEQPEFTSVALCVDKEEIGSKGNTGMHSKFFENTVAELIALEGDYCDIKVRRALANSK
                     VLSADVSAGYDPNFGEAYEKRNSAYMGNGVVLTKYTGSRGKSGCNDANAEFMSEVKRI
                     FNKGNVVWQTAELGKVDQGGGGTIAHILANQGAEVIDCGVGVLNMHAPHEIVSKVDIY
                     EMYKGYKAFFNINL"
     gene            43658..43843
                     /locus_tag="KOU88_002247"
                     /pseudo
     CDS             43658..43843
                     /locus_tag="KOU88_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            complement(43951..45117)
                     /locus_tag="KOU88_002248"
     CDS             complement(43951..45117)
                     /locus_tag="KOU88_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017752472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK3212122.1"
                     /translation="MKGGVRKRGKKWYYYFDAGIVDGKRKKVERVGGNTKKEAEKSLR
                     DAINEYENAGIVFDETNMSLSDYLNFWYKEYVLLNCKYNTQESYRNLIENHIEPRLGK
                     CKLKSINPAIIQEFLNNKSKETYTQNGEEKHYTKGVLKAIYVVLNAALKSAVYPYKLI
                     KENPVQYASIPKNVLKVKNESDNKTITLDEFNKILEIYPKNTNIYIPLLIGFHTGMRK
                     GEILGLCWDNVDLDNNIIKVRKNLIKRKVSEFELASPKTKTSIRDIKIGDTLSRILKE
                     EKLNQKKQKIKIGKWYKETEYDWVCRKKDGSFVNHNNIDAAIRTINKKLNINFNFHCL
                     RHTHATLLLENGANVKYIQQRLGHSQLSTTMDTYSHVTSKMESETIDILEGILQ"
     gene            complement(45255..45461)
                     /locus_tag="KOU88_002249"
     CDS             complement(45255..45461)
                     /locus_tag="KOU88_002249"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212123.1"
                     /translation="MNLSFNKKKKFELSKEELELIENWLGNKYAGDMTIPAIVDFSLE
                     TDIEYEKIVVYLAEKVLESRDKKH"
     gene            complement(45520..45741)
                     /locus_tag="KOU88_002250"
     CDS             complement(45520..45741)
                     /locus_tag="KOU88_002250"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212124.1"
                     /translation="MLKELRKKKKLTQIELAKRVGCHRSQISRLENNENKDLTIPALI
                     ELEIALGLEEKYLVNYFADEYIKKRKLHK"
     gene            46025..46162
                     /locus_tag="KOU88_002251"
     CDS             46025..46162
                     /locus_tag="KOU88_002251"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212125.1"
                     /translation="MNKTKYYDILKLNLLMKKLKELDKNKINEYKIKVKEIHKINKKE
                     E"
     gene            complement(46199..46594)
                     /locus_tag="KOU88_002252"
     CDS             complement(46199..46594)
                     /locus_tag="KOU88_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212126.1"
                     /translation="MNRIKELREEKGISLDKLSEDLHINKSTLSRIENGLREPKKSTI
                     EEYANYFDVSTDYLLGRTDVRNSLFINKNEKDYDAENFKTEKELIENMYLDEDMKEVF
                     NIFSELSPDAREKALKVAELFLLDEKNKK"
     gene            46773..47006
                     /locus_tag="KOU88_002253"
     CDS             46773..47006
                     /locus_tag="KOU88_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HBK3212127.1"
                     /translation="MYLNRLEGLMKENRHTQKNVADILGLSSYGFRLKLKGKNEFKAS
                     EIKKISKLYNVSADYFFSDEVAKIAIKEERGNK"
     gene            47006..47758
                     /locus_tag="KOU88_002254"
     CDS             47006..47758
                     /locus_tag="KOU88_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBK3212128.1"
                     /translation="MKNLTIIKQNNQFLVESREVAELIEKKHDNLLRDIRGYKKILED
                     SSNLKSQDFFIESTYINTQNKIQPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MERELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQVMKPKADYFDALVERNLLTN
                     IRDTAKELGVKEKTFVLWLIEKKYCYRDLKGKIKPYSNKMQYFELKEFTTPYGHSDTQ
                     TLINPKGREAFRLLLIKDGLVKEKEYQITLLG"
     gene            47803..48057
                     /locus_tag="KOU88_002255"
     CDS             47803..48057
                     /locus_tag="KOU88_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212129.1"
                     /translation="MSEDIFYGIKNTLDEIAEVQIKNKQGVLKEVGMLISGEDNSCIT
                     HCLDEDLIKFYIKEEAVLTIDKDSHLLCMLDALFYNFLDK"
     gene            48085..48528
                     /locus_tag="KOU88_002256"
     CDS             48085..48528
                     /locus_tag="KOU88_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212130.1"
                     /translation="MKKLGNISNFNLDKQEDKSFNDLDNISICFSEGIRKVVEMNLNN
                     YKNKISKYLNETSKIELLEPKELTIVISKGYPDYLMSVEEASKRLKIDKVFGYELIKN
                     GLLKSVDIGATKVSSYELDDFITRNQGKNIKEMLREMKELREGVI"
     gene            48656..48844
                     /locus_tag="KOU88_002257"
     CDS             48656..48844
                     /locus_tag="KOU88_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212131.1"
                     /translation="MKIIYKNKVYKVEQDKKLFRITYYDEQRGSKKFNKEKKVKRSVL
                     TRDIELVNLYLPAHLKIK"
     gene            complement(48979..49149)
                     /locus_tag="KOU88_002258"
     CDS             complement(48979..49149)
                     /locus_tag="KOU88_002258"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212132.1"
                     /translation="MSNKDIYTREEDKRFTLRINKLLFEKIEQLAQKDKRSIGREIEF
                     ILEKYFEDNPLE"
     gene            49292..49450
                     /locus_tag="KOU88_002259"
     CDS             49292..49450
                     /locus_tag="KOU88_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBK3212133.1"
                     /translation="MTNERVRFTFRLPAPLLEKIKNRASIEGSSMNSLILHILWDYIK
                     EIENKEVK"
     gene            49450..49677
                     /locus_tag="KOU88_002260"
     CDS             49450..49677
                     /locus_tag="KOU88_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212134.1"
                     /translation="MVELVKEFDLQTIKVGNAVKVNCKRFGFEIDCIVVVATEKELNL
                     AYFDEGRGCMEYQALITEDIQDGDYEIKILS"
     gene            49776..50018
                     /locus_tag="KOU88_002261"
     CDS             49776..50018
                     /locus_tag="KOU88_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212135.1"
                     /translation="MEAARLIAMGQIKQAEKEISKLQGTKNNSSLMWWEAVKFASQNI
                     LQGLEHDIELEASTDFREFMITQEELERDRPIDVQI"
     gene            50102..50611
                     /locus_tag="KOU88_002262"
     CDS             50102..50611
                     /locus_tag="KOU88_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus Gp157 family protein"
                     /protein_id="HBK3212136.1"
                     /translation="MSTLYELTTDLLEIEEGLTEITGNEAEKLEEIKEIIKQEIQNKN
                     TRIVSVILNIDSDINSIDSEIKRLQELKRVKKNTLDRLKSNIKDCMELLGTKKVETVL
                     GNISIRKSAGSLVIEDEEKIPAIYKTVEQVVKVDKNIIKDFIKKGHEVEGCRIEYGTT
                     LTIPKAKKE"
     gene            50621..51229
                     /locus_tag="KOU88_002263"
     CDS             50621..51229
                     /locus_tag="KOU88_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBK3212137.1"
                     /translation="METNNVYIKLVNIQSTLKAPKSQFNSFGKYNYRSCEDILEGLKP
                     ILKEEKALVILDDNIVQIGNRFYVEATATLIDAETGEKVSTKALAREDETKKGMDLAQ
                     VTGSVSSYARKYALNGLFCIDDTKDSDATNKHGNEQKKKEVNESELNTLYSLGESIEK
                     DKNRVDSEVYKKFGKLAVDLTKQEYEKVLNGYKSILEKQKQE"
     gene            51239..52120
                     /locus_tag="KOU88_002264"
     CDS             51239..52120
                     /locus_tag="KOU88_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBK3212138.1"
                     /translation="MGIIRVSKDKDNPYVVLNKTCLEDVKLSWQAKGLHSYLISKPDH
                     WKIYVNDLCKRSKNGRDATANILKELIENGYITRKPCRDSNTNKMLGGYDYEVYEIPL
                     ENPQKLKSRKTDFPETGFPGNRVSRKPENTEVVSNDFKVNNDITTIVINEQSNKDKTT
                     YIKKYFEKYIGVITPNNFIELMSYLDDGMEADVIIRAIDEAISNGVKNYKYVKTILNN
                     WIEAGVKTNLELTEYQNEFERKKKSKQEKKQSNNKAVNTHNVNKNKFANFNQTFTQYE
                     EKELDEIIKKSQKEKFK"
     gene            52180..52353
                     /locus_tag="KOU88_002265"
     CDS             52180..52353
                     /locus_tag="KOU88_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBK3212139.1"
                     /translation="MARIYAQRSGSLNEQDRLELLRLLGKAGYTVKIAREKQNSKTTY
                     TYFVEYTEEQEEK"
     gene            52369..52776
                     /locus_tag="KOU88_002266"
     CDS             52369..52776
                     /locus_tag="KOU88_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK3212140.1"
                     /translation="MNTITLVGRLVADAELKYLPNSGTPKITFSMAVDRRFKDKNGNK
                     ITDFIQCEQLGKHVENLVQYLVKGKPIYAVGELNIYNYKDENGCWKSITKVNVNALEL
                     LSSKNDNNAKQEYVPPGLDPQGFQAIDDDDIPF"
     gene            52846..53007
                     /locus_tag="KOU88_002267"
     CDS             52846..53007
                     /locus_tag="KOU88_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212141.1"
                     /translation="MSRTAICSVCGEFLVDSYGDKFTNAKVIDLYGREFVIVICKSCL
                     EELLRKCED"
     gene            53012..53233
                     /locus_tag="KOU88_002268"
     CDS             53012..53233
                     /locus_tag="KOU88_002268"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212142.1"
                     /translation="MRFEIGKTYKFDKEKFMEINGVEQHKKYKELWIDDIEGVEFTVE
                     KTFDDGYVCYPNEFWFNFGVVSEWCVEVK"
BASE COUNT        21587 a         5593 c         9381 g        16706 t
ORIGIN      
        1 gataaattaa aatatttttc ttatagtcaa aattcaatta acacatataa atcatgtcca
       61 ttgaaattta aatataaata tattgataga ataaattgga aaaatgatga tgttggtagt
      121 agagagtatt atgaaacttt aaaaacagga agagattttc atttgatttg tgaaagatat
      181 tttagcaata tacctcttgg aatctatttt aatgaggatg ataaaaatag taaaaagttt
      241 ttaaagtgga tggaaaatat aaaaaaagtt gttcctattg aaaaaggaaa aacgtatttg
      301 ccagaatatg aagtaaggat gacattaaat ggggatataa tacaggcaaa gtatgattta
      361 gttgtaattg gaaataacaa tatagaaata tgggattgga aaaccgagtc taaaaagatt
      421 gactataaac acgtagaaaa tagaatacaa actattgttt atatgttttt agcaaaagaa
      481 gtaataccta aagttttaaa aatggacata aatgttaaag atataaatat gagatattat
      541 caacctgaat ttgatgactt accaattacc attttatatg atgaagaaaa acatgaagca
      601 aatagaaata aaattcaaaa ttatataagt atgataaaaa acactaatta tgaagaacat
      661 acatacgaag acaatctata caatgatata gaaaaggtat ataataaaga agaacgtatg
      721 tgctatagaa ataaaaagca ttgcaagtat tgtgaattta ataagttatg taatggcaaa
      781 gaaatagatt atagtatttt ggaggcggaa atttatggga cttaggtttg tattaggtag
      841 aagtggaagt ggaaaatcca cctatatact agatgagatt aaaaaagaag ctcaaaaaaa
      901 tgaaacgaca tcaattatac ttttagttcc agaacagtac acatttgagg ctgaaaatag
      961 agtaagtaag ctattcttag gaaaagaaaa agataagtat ctaagagtta gggtacttag
     1021 ctttaagaca ctaagtaata tagttttttc tcaagtagga ggattgacag atgtaaatat
     1081 aaattctagt ggaaaagcaa tgatggtata tagagctatt gaagatgtaa gtgaagaatt
     1141 aaatgtgttt tcaaaatcaa aatcgcagtc tggttttgta agctcaatta cagatatgat
     1201 atcagaaatg aaacaataca atataagccc tgaaatgtta gaaaatatat ctggagaatt
     1261 ggataatgaa actttaagtt taaaattaaa agatataagt aaaatatata attcttttga
     1321 agggaaattg catgaaaatt atgtagatgc tcaagatatg ttaacttcat tggcaagtaa
     1381 aattgaatta agcagttatt tagatggagc ttgtgtttat atagatgaat ttacaggttt
     1441 tacaccaaat cagtacaatg tcataaagag tatattaaat aagtctaaaa gtgttaatat
     1501 ctctttgact gtagatgata tcaactatat tgggtacagt aaatctgata tgttttctag
     1561 aacgaaattt acttattcaa aattgactca attgtgcaac gaagaaggca taaaaatatt
     1621 gccacaagta aatttaaaca caggtgttat aaaaagattt gaaaaagtta aggaattaca
     1681 gcacttagaa agattttata atgcttatcc atataaaata tattcaaatc caactgaaaa
     1741 tataaagata aaagagttta acaatttata ttcagaggtg gaagagatag ccagagaaat
     1801 tgtacattta gttagagata agaatgtaag atatagagat ataaccattg ctacaagaga
     1861 tttaaataga tatgattttt tagtacactc tatatttaat gaatataata taccaaactt
     1921 tatagataag aagagagagg caaaaagtaa tccaatagtt attttaatta tttcagcttt
     1981 agaaatgaag aatagacgat atgggtatga aactatgttt aggtatttaa aaagtggact
     2041 tataggaatt gataatgatg atataaattt actagaaaat tatgtgttgg ctaatgggat
     2101 taaaggtaaa aaatggtttg atgaaaaatg ggattataga ataacccaaa gtctttcagg
     2161 tcaagaaagt gaatttgaac tggaattaaa agagaaaata aatgaaataa aaaatagagt
     2221 attagagcct atagtaattt tacaagaaaa attaagagga aaaaatagag taaaagaaat
     2281 ctgtagatat atatatgaat ttttattaga tataaatatg ccagaaacta tagaaagttt
     2341 aataataaat tttaaggata aaggggaact tgatgttgca aatcaatact cacaagtttg
     2401 ggacatagta gtggacatat tagaccaaat ggtggaactt atgggtgatg aaataatttc
     2461 tttagaaaaa tttataaaat taataacctt aggttttgat gaatatgaat taggactggt
     2521 tcctcctagt atagaccagg tacttgtaag tagtgtggat agaatgaaaa atccagacac
     2581 gaaatattta tacctagttg gaactactga tggtgtgttt ccgctgatta caaaggatag
     2641 tggaatattg agtgataatg atagggaaag tcttggaaac aaaggaatcg aagttgatat
     2701 tgatagtaag actaggagtt ttgaagaaca gtttcttgta tataaagctc ttacttcgac
     2761 atctaagaat ttaaccataa catatccaat atcagaccat gaaggtaaaa cgcttagacc
     2821 atcaataatt atatcaagac ttaagaagat atttccaaat atagaaaata aaagttattt
     2881 agtggaagaa aataaaagca ctgataaaga tatacttaaa aaaataacgg ttaaatcccc
     2941 tacatttaat gaacttataa acgtaataaa aaattatgac agtgatggtt acaatacaga
     3001 agagattaat agtatttggt tagatatata taggtactat ttaaaagatg aaatctatag
     3061 ttctataaca aaaaaagtta taaaaggtct tagttatact aatcaagttc ataagattga
     3121 agagaaaaaa ataaggtcat tgtataaaag taattctctt agcatatcta ggcttgaaaa
     3181 atatgctgaa tgtccatttg cttattttat acaatatggt ctaaaagcaa aaaagcgtaa
     3241 agagtattca tttacaccac cagatttagg aacttttatt cataatattt tagataggtt
     3301 ttcaaaagaa cttttacaag ataatttaac ttggagagat attgatgaaa aatatataga
     3361 attaaagata ggtataatag ttgatgaaat aattttaaag ataccaggat atatattaaa
     3421 tagttctgag aggtataaat accttgcata tagattaaag aatatgttga caactgctat
     3481 aactataatt agtcagcaaa taaaacaagg ttcatttgaa ccaatagatt atgaagttaa
     3541 atttggcaac aatggaaaat atccacctat aaaaatggtg ttagaaaatg gacaagaagt
     3601 aagtttaatt ggacaaatag atagagttga tgaatttgaa gaaggagaaa ataaatatat
     3661 aagaataata gattataagt caggcaataa gtccataagt ctaacagaaa tatattatgg
     3721 tctacaatta caattacttg tgtatttaga tgcaatcctt gaaagtgcaa aggatgaaga
     3781 tataaatata aatccagctg caatactata ttgtagaata aataatccaa tagcaaaatt
     3841 taatgaagat aaagatgatg aagaaataca agaagcaata ttaaaagaac ttagaatgaa
     3901 ggggcttgta gtaaaagact ctcacatagt taaagagatg gataaatcat taatagatgg
     3961 agaaaggaaa aactctttag taataccagt aggtcttact aaggatggaa atgtaggtaa
     4021 aagtacttca gcaataagct atgaggattt caaactgctt agaaaatatg taaggcatgc
     4081 tataaaggat ttatgtgaag aaatgttaag tggagaaata cgtatagctc catataaaca
     4141 taaagatgga acatcatgtg acttttgtga ttactctgct atatgtcagt ttgattcaac
     4201 tataaaagat aacaagtata aaaatttaaa taataagagt aatgaagaga taataaaaat
     4261 gatgaaagga gatgttaatt agtgagttct cctaaatgga caaaagagca attagaagtt
     4321 atagaaagta gagaatgcaa tttattggtt gctgctgctg ctggttcagg aaaaacagcc
     4381 gtgctagttg agcgtataat tcaaatgata acaagtagag aaaatccaat tgatatagat
     4441 aagttattag ttgttacatt tactaatgct gctgcgtcag aaatgagaga gaggataggg
     4501 gatgctatag gaaaagcctt agatgaaaac ccagaaaata aacatttaca aaaccaactt
     4561 gttttattaa ataaatctag tattacaaca atacactcat tctgtttgga tgttataaaa
     4621 tcaaactttc atagaataaa cttagaccct aatttcagaa taggagacca aactgaatgt
     4681 gctattttga aacaagaagc aatagaggaa gtatttgaag atttatatga agaaagagat
     4741 gaggggtttt taaatttagt tgaaagttat gcagaaagag gaggagataa agaagtacaa
     4801 gatattatct tgggaatata ttcatttgca atggcttctc ctgaacctaa aaaatggttg
     4861 attgactcag cagaacgatt taatattgat gaaaattttg atttttcaca gtctatttgg
     4921 gctagagcta tattagatac tgtaaaaata gagattaatg gtctttgtct aaatatggaa
     4981 agggcattaa aagaagtgga atcaatagaa gaattagaaa cttttgcaga aaagttatcc
     5041 gttgaatata aaaaaattgc tgacatttca caagcatgta ataaatcttg ggatgaggca
     5101 tataaaaaga tggcaagtat gtcctttgaa aattatgtaa aaggagtaaa aagaatttca
     5161 aaagatgctc cttcgtatat aaaagaatca aaagaaaagg caaaaactat aagagataag
     5221 actaagaaat ctttagaaag tatagtaagt gctacattca ataaagataa tgattctatt
     5281 agagaagaaa taaaatatct ttataacata gttaaaccaa tatctagtgt tgtactgaga
     5341 tttgaagagg aatatagcaa taagaaaaga gaaaaaggaa taatagattt taacgatata
     5401 gagcattttg cattaaatat acttacagat gtagatgaaa aaggtaatat tgtaccttct
     5461 gatatagcag ttggatatag aaacaagttt tatgaaatat ttatagatga atatcaggat
     5521 agtaatctag tgcaggaagt actgcttaaa gctgttgcaa atacagaaac tccaaataga
     5581 tttatggttg gtgatgtaaa acagagtata tatagattta gacaagcaaa gccagaatta
     5641 tttttgcaaa aatataataa ctataatgat aaaaagggaa gttcccatag aaaaataatg
     5701 ctttacaaaa attttagaag tagagaagaa gttgtagatg ctgtaaatta tatatttgaa
     5761 aatataatga atgagaatat aggagaaatt gaatatacag aaaaagaaag actaaattta
     5821 ggtgcaaatt ttaatgtgga tacagacgag aaatctatta ttggtggagc aacggagata
     5881 cacctaatac aaaaagataa taaacttgat gatgatatta taaatgataa agacgataga
     5941 attaataaca aagaaaatga aatagaggaa gaagaaaaat tagataatat acaacttgag
     6001 gctagaatgg ttggaaacat tatcaaagat ttaatgaaag tcaatgaaga tggaaaaatt
     6061 caaaaggtct atgataaggg aatagatgga tatagacctg tggaatttag agatatagtt
     6121 attcttttaa gagctacatc tgcatgggct ccagtgtttg cagatgaatt gatgaatatg
     6181 gatataccaa catatgctga tgttggagtg gggtattttg atacgattga aataaaaaca
     6241 atattgtcat tacttcaaat aatagataat ccaatgcaag atatacctct tatatctgta
     6301 ttaaaatcac ctatatttgg atttacacca gaggatttga ttgatattag agttcagagt
     6361 aaagataaaa ttttttatga ggttttaaaa agtacagcag agtatgatgg atttacagat
     6421 tctcaaaatg aaaatgagtc tgagtttata ccaagtgaag agtgcataaa caaaagtaaa
     6481 gattttttaa ttaagctaaa ggaatttaaa gaaaagtcaa tgtacatgag tacagatgaa
     6541 tttatatggt acttgtacac aaggactgga tactatgcct atgttggagc attgccaggt
     6601 ggaagtcaaa gacaagctaa tttaaaagta ttgtttgaga gagcaaaaca atttgaagaa
     6661 accagtctta aaggaatatt caactttgta aattttatag agaaattaaa aaaatctagt
     6721 tctgatatgg gaagtgcaaa aacacttggt gagaatgcaa atgttgttag aataatgagt
     6781 attcataaaa gtaaaggttt agaatttcca gtagtcatat gctctgcaat gggtaaaaat
     6841 ttcaatactc aagattttaa aaagagtatt ttatatcatc ataatttagg gtatggacct
     6901 caatttgtag actatgagag aaggatttct tttccaagta tagccaaaga agcattaaaa
     6961 agcaaaataa atatagaaaa tttatcagaa gagatgagag ttttatatgt tgcatttaca
     7021 agagctaaag aaaaattgat tataactggt tctactagaa atatacaaga tagtataaag
     7081 agatggtcaa atggaattga aagtttagat acaatatcac aatacgagat attaaaaggt
     7141 aaaaattttt tagattggat aatgccttgt gtattaagac atagggattt atctaatcta
     7201 ctagaagaag taggattaga cgcagttttt aatgttgaac ataattcaaa atggtatgga
     7261 aagttgtgga ataagaatga tattttagtg gaaaagaaga gtgatgaaga aaaagaaagt
     7321 attgaagaaa ttcttgaaaa aatagatgta gataatcctg acagtgatta ttacagtgaa
     7381 atagaagaaa aattaaacta tatatatcca tatgaattta gtacaagaaa acctgctact
     7441 atatctgtta cagaaataaa aaagatacaa aataattatg aagaagagtt aataaatact
     7501 atatttgaac aaaaagtaat attaaaaaag cctctattta ttcaaaatga agaagaaaga
     7561 gaaaaaataa gtggaacaga aagaggtaca atagtccatt tagttatgga ggttttagac
     7621 ttaaaaaatg taagtagtgt aaatgatata aaatcacaaa taagaggttt tgtttcaaaa
     7681 ggtataataa cagaaaaaca agctagtata gtaaatccat ataaaatata taaatttttt
     7741 gcctctaaca taggaaaaag aatgttgaat gctgaaatta taaatagaga aaaatcaatt
     7801 tatgcacaag taaatatgaa agacatatat atttatgaaa agcttataaa caatgatgat
     7861 aaaaaacttt atgataatga aagtgtcatg ttaagaggta tagttgatgc ttattttgaa
     7921 gaagataatc aaatagtttt ggtggattat aaaacagatt ttgtaaatga ggaaaatata
     7981 aatcaaataa tagagaaata taaaaaacag ttggatttat atgcagatat tattgaaact
     8041 ttaactggta agtcagtaaa agagaaatgt atatatttat ttggagttga tgaagctgtt
     8101 tgttattagt ttttatatat aaattaaacc taaaagatag aggaagggga aaaaatgaga
     8161 tttattcata catcagattg gcatctaggg aagtccctag aaggccattc tagaattgag
     8221 gaacaagcaa agttttgtga ggaatttata aaaatagtag aatcaaatga aatagatatg
     8281 gttataattg ctggagatgt atatgatact tctaatccac cagcacaagc agaaaaacta
     8341 ttttatcaga ctgtatcaag acttgccaat aatggtcaga ggtgtgtatt aataatttca
     8401 ggaaatcatg ataatccaga gagactctct gcaataacac ctctagcaca tgaacaggga
     8461 atacttatat atggttatcc attaagtgct acgatagaag ctaagtataa agggtttgaa
     8521 ataacatatg caactcaggg atgtacaaaa ctgaatataa atggagaaaa tattgtggtt
     8581 gctacattac cttatccaag tgaaaaaaga ttaaatgaag ttttttcaag tgaagatgag
     8641 tttgagaaac aaaaaaatta ttctgaaaag gtaggagata tatttagaag tttagaagaa
     8701 aattttagaa gtgatactat aaatatagcc gtatcacata tatttgtaat aggtggagag
     8761 agtactgaat cagaaagacc tatacaatta ggtggaagtt ttttagttga aagaaaagat
     8821 ttgccagaaa aggctcaata tactgcacta ggtcatttac ataaacaaca aaaagcttcc
     8881 gaacgtttaa atgcatacta ttctggttct ccacttcaat atagcaagga tgaaagagcg
     8941 tataccaaag gggcatacat agtggatata aaagctggtg aaaaaccaat aattgaagat
     9001 gtatatttta ataattacaa acctatagaa gtatttaaat gtaatggaat agaagaagca
     9061 ctagatatat gtgagcaaaa tcaagataga gagatttggt catattttga aataaatact
     9121 gatgagataa tatcacagaa tgaaattaaa aaaatgaagg aactattaaa agacataata
     9181 gaaataaaac caataataac atcttgttat gaacaagaaa gtgtagatat aaaagaaaag
     9241 tctatggcag agttgtttag agagttctat tcttttagta aaggtgtaga gccaaaagga
     9301 gaacttatgg atttatttct agatataata agtgaagaag gtgaatcagc agatgagacc
     9361 aattagatta gaacttacag ggcttaatag ctatattgat aaacaagtta tagactttga
     9421 aaaattaatt gaaagaggtt tgtttgggat atttggaact actggaagtg gaaaatctac
     9481 aatcttagat gcaataacta ttgctatgta tggaaatata tccagaaata caaaagaata
     9541 tataaacagt gtgtgcgata aggcaattat atcatacgag tttgagatag gaagcaaaaa
     9601 cactagaaga agatacattg tagatagaac cattgctaga agcaaaacag gaacaaagac
     9661 ctctaatgct agattaatag aagtattgaa tgacaatacc caaaatgttt tagctgataa
     9721 agttgtggaa gtaaatgaaa aagtagcgca ggtcgtagga ttaacggcaa atgattttac
     9781 taggtcagta gttttaccac aagacaaatt taatgagttt ctaagattat cacgtgcaga
     9841 tagaagagac atgttagaga gaatttttaa tcttgagaaa tatggaagaa gtcttggcga
     9901 aaaagtgaaa aagagaaaaa atatacagtt acaaaattta aaagatttga aatcaaaatt
     9961 aagtcaatat gatggaatta cagaggaagt atataacaat ataaaccaag aattaataga
    10021 gttaaaaaat ttggaaaaag ataagaataa tgctttagac ctagctcaaa aatcttatga
    10081 agaaagtaaa acagtatatg aagaacaatt aaagttagaa aaaaatgaac ttagaaaaaa
    10141 tgagcttgat ttaaaaaata gtgagataaa agaaaagatt gctcttgtag aaaatgatag
    10201 taacgctaaa aaggtagacc catacataag ttcagttcaa aatctagaaa aaaagataga
    10261 tgaagatagc ttcgcagtaa gtaatttaga aaagaaatta gcaatattaa atcaggagct
    10321 tgaagttaca aaaaatagat ataaaaaaat aaacaaaatt aagaatgaag aaatccctaa
    10381 attgagtgaa gaaaaaataa gattgcaaca agcaataaaa ttagaagaag agttagtttt
    10441 attagataga gagttaaaag agctaaaaga aagtggaatt aatttaaata agactaaagt
    10501 tgaattagaa aaagtaaagc aggtgtcaga gtccagaaaa gatgcagtta ctaaatctat
    10561 aaaagaagtt gaaggaaaga ttgataaagt aaatataagt gcagaattaa aacaaaaaat
    10621 atttctagca tatgaatacg agaaagatta caacaacgta ttggaagaaa aaaatcaaaa
    10681 gctaaataaa ctagaagaaa tactcaaaga gacagaaaat ataaatttaa aagttagata
    10741 tattgataaa gataagaatg atgtaaatcg taatttagaa aatttatcac ttcacttgga
    10801 tgttcttctt aaaaaatgtc ctggtaagag tgctgattta cttttaaaat ctgaatatgt
    10861 tactgaatta agaaataaag caaataatac taaagaaaat gaaattaaga aaagcagtat
    10921 acaagatgaa ttaaagataa tacttgaaag taagtttaat actgaaaggg aagtaaattt
    10981 actaaatgaa aaacttgaaa ataatagaaa gaacagagat gacctagaaa aagaattaga
    11041 agaactaaag tatttaaatt tagcctctga acttagacgt gaattaaaag aaaatatgcc
    11101 ttgtccagtt tgtgggtcaa aacatcatga aaatcataat ataactaaat atgatgaaaa
    11161 tatatctttt gtcaaagaaa aactggagaa attagaaaaa gaaaaaataa gtataagaaa
    11221 caatatagag gaattaaatg ctaaagtaag tgggtattta tctatagaaa aaatgaagac
    11281 taaagaactt gaagatgtaa aaggaaaact aggggggatt ccatctagtc aattattaaa
    11341 aaaacttgat gaagaacaaa gaaaacttgc attgttaaaa tctaatattc aggagtggga
    11401 gaaagaaaaa gagagtactg aaaataaagt aacattagcg aaagaagaaa aaaataaaat
    11461 tgaaaaagaa gaattaaaaa taagagagag tctgaataat tataagaaat taacaagaga
    11521 tttaaacata gaaatagaag gtttagaaaa taaatgtaaa aaacttaaac aggaatacct
    11581 aggattaaag acgattacta aagtctctaa tctattgtca aaagtaaaag aaataagaga
    11641 gaatgaaaaa gaattagaat tactaagtac tgggcattca aatttattaa aaaatagaga
    11701 ctcactagat attaaaataa gagaaaatga gagtaaacta catgaaatag agatagaatt
    11761 aataaaggct agagaattat atgtagaaaa gaaattgagt agggataata agtataaaga
    11821 agttattagc ataactaaag gtgatttagc taaaaatctt ttacataatg ttgaagaaaa
    11881 tatatgtaag atattagaac aagaagaatc aagtaagaaa aaattggaag agcaaagatt
    11941 agaatatgaa aaaaacattg ctgaaaagca caatatagat ggtagactta aaactgctaa
    12001 ggaacaatat aaagaccaaa aatcaacact aaataaacta ttagcagaaa ataaatttga
    12061 aagtatatat gcagtaaaaa gagctttatt agatactgat gcagtaaaaa aattgattga
    12121 agaaatacta gagcatgaag aagaacaaaa gttattatca tttaaaataa aatcatcaaa
    12181 agaaaaatta aatggaagaa gcataaagaa ggagtacttt gaacagttaa aagatgaaat
    12241 ttataatttg aaagtagaaa taggaaatat atccaaagat attggagcta atcaaaatca
    12301 gttaataaca ttaaaagact ctttagataa gataaatgat tttaataaac aacttaaggt
    12361 agttgaacac aatgtggact tattggaaga attagataaa tgtgtacaag gaaataaatt
    12421 tgtagaatat gtttctacaa accaattaaa atatatagcg ttggaagcat caaaacgatt
    12481 ggatggaata acaaaaggaa gatatgcact tgaaattgac tcaacactaa actttgtaat
    12541 gagagataac tttaatggag gagaaagaag aagcattgat actctatctg gtggagagac
    12601 attcttgaca tctctatcat tagcacttgc tctttcatct caaatacaat taaagggaag
    12661 tgcaccatta gaatttttct ttttagatga aggttttggt tcattagata gtgaactttt
    12721 agaaattgtt atagaatcat tggaaagatt gcatagtaat aatctaagtg tgggtataat
    12781 aagtcatgtc gaggaactta aaaatagagt tcctgttaag ctattagttt catctagtga
    12841 ggctggaata ggttcaaaag taaaaattga atatagttag aaaatatatg ttaattgaat
    12901 atattatcta atatttccaa ataatatgta attgtgatat aataaaaact aatattaaag
    12961 ttatttataa ttaatattaa tataaaaaca tgtaagtagg agtgtggtaa gtgttggaat
    13021 cgcccaataa tttgattcag attatttttt taatagtatt acttataggg tctgcatttt
    13081 tctcagcatc tgaaacggcc ttaatgtcgt tgagtaaaat cagaatcaga tatatgcaag
    13141 atgaaggagt taaaggagct aagttagtaa gttcattaat agaaaatcca aataagcttt
    13201 taagttctat attggttgga aataacgtcg taaatatagc agcaacatcc atatcaacat
    13261 ctttgtttat aggattaatg ggagaaaaag gagtggcact tgctacagct gttatgacag
    13321 tattagtatt aatatttggt gagattactc caaaaacaat agcagcaaat aattcagaaa
    13381 aggtttctct attagtatct aaacctataa aagcaattat atttatatta agaccaatag
    13441 tatggatatt taatataatt acaaatatta tatttaaatt atttggtata acaaataaag
    13501 gagctaaatc attcataact gaagaagagc taaaaactat ggtaaatgta agtcatgaag
    13561 aaggcgtcct tgaaatggaa gagagagaaa tcataaataa tgtttttgaa tttggagata
    13621 tgcaagctaa aaatgcaatg gtacaaagaa tagatatggt agctatagat atggaagata
    13681 gttatgatga gataatacag gtatttaaaa ctgaaaaatt aagtagaatg cctgtgtatg
    13741 aagaaactat agatgatatt gtaggaatac ttaatataaa agatattata tttttatctg
    13801 atgaagaaat agagtcattt gatattaaaa attatatgag agaacctttt ttcacgtatg
    13861 agttcaaaaa gataacacaa cttcttgaag agatgaaact tgaaaaaagt cagatggcta
    13921 tagttgtaga tgagtatggt ggaacatctg gacttttaac tatagaagat ttagtagaag
    13981 tcattgttgg agatatagag gatgaatatg atgaagaaga ggatgaaata caagttataa
    14041 aagaagatga gtatattgta gatggaagta ctaaaattgg tgatgttaat gaacttattg
    14101 gtgtaaactt ggaatctgag gagtttgatt ccataggagg ttttataatt ggacacctaa
    14161 gcagattgcc agaagaaaat gaagtaattg aagttgataa tataagattt tgtatagaaa
    14221 gtatagaaaa aaatagaatt aaaaaaataa gaatatatac ataatgtaat aatgttctta
    14281 aatttattag aagtgtataa atataaaaga tatcttttat atttatacac ttctttttat
    14341 tttgtattca aataaaacta gtatgaaatg gacaaaataa aaatataaat tagaagaaag
    14401 gagattttta agatgagcat actagaaaat aattttttat acaaattaaa aaacaacact
    14461 atcttttttt gtatatatac attgttattt atttttattt acaaagcgtt tccatacata
    14521 gctccatttt ttctaggtgc tataatagca cttatgatta atcctatatc acaaaagtta
    14581 gaaaataagt ttcgtataaa taaaggtatc tctactcttg ttctaagttt tcttgcagtg
    14641 gctatagtca gtacagttac tacaataata gtaataaatt caatgaaaga attaatggga
    14701 tttttaaata atatatctgc taatcctgag gatataagta atactattat gtatttttta
    14761 aataaaataa atgactttat gaaatcattt caagaaatag ccaattttga tgtagaacaa
    14821 ttagtaaaca aattcagtgg tgaagtaatg caaattacaa aaaatcttct tactagtata
    14881 cttggattgg ctacttctat tccatatatt ataatattta taattacctt gtttattgct
    14941 acgtacttta tagcaaaaga ccttgataag attgaaaata gtttttataa tatgtttact
    15001 gttgatgtta gaaagaaggt aaaaaacgta aagaaagagg cagggctttc acttgttgga
    15061 tatataaggg cctatacaat acttatggct ataacatttt ttgcaatctg gggaagtttt
    15121 gctttatttg gattgaaata cggtctaata gtagggtttg taggagcttt aatggattta
    15181 attccattcc taggtataat aacaatatat cttccagtaa ttgtttatta ttttcttata
    15241 aaaaattatt ttatagctat aagtatgact gtgatatttt ttgttttgtc tttgattaga
    15301 gaaatacttg aacctaaact agtatcagta aatgttggac taaatccatt agctacccta
    15361 gcagcgattt ttattggaat ccaagtaaaa ggaataattg gagtaatttt ttgtttgggt
    15421 ttggtatgta tgcatgatat acttaagaag gtggatattt tttaattata ataattgata
    15481 gattttttta aaaataaaat tttattcaca ggtaaataaa aaaatattaa tcttattaag
    15541 aaagagggta tatacgtgaa acaaaaagta gtggaaagat ttttaaaata tgtatcattt
    15601 gatacaacat ctaattctca gtgtgagaac tgtccatctt cagaaggtca aagagtttta
    15661 gctaagtata tagttgaaga gctaaaaaca atgggtgttg atgatgtgag tttagatgaa
    15721 aatagttata taatggctac tttaaaagga aatactgatg gtgtggatac tataggattc
    15781 atatcacatt tagatacaat tgaagatgtt agtggaaaag atattaaacc aagaataata
    15841 gaaaattatg acggaaaaga catagtttta aatgaagcgt taaatgttat tacgtatgta
    15901 aaggattctc cagagttgga agaatttaaa ggtgacgatt taatagtcac tgatggaaca
    15961 actctacttg gctctgatga taaagctggt atagctgaga tagtgactgc aatagagtat
    16021 ctaataaatc atccagaaat taagcatgga gatataaaaa taggatttac accagatgaa
    16081 gaaattggta gaggtgctga tttatttgat gttgaaaaat ttggagcaaa atatgcatat
    16141 actttagatg gaggaatagt tggagaactt gaatgtgaaa attttaatgc tgcaaatgca
    16201 actattacta tacatggtag aaatgttcat ccaggttcag ctaaaaataa aatggtaaat
    16261 gctatacata tagctgctga aatatcagaa atgttcccag cagatgaaag accagaaaca
    16321 acagaaggat atgaaggatt ttggcattta aattctatag gtggaaatgt cgagaatgta
    16381 agtatggctt atattattag agaccattgt aaagaaaaat ttgaaaatag aaaatctatt
    16441 atgatagaga atatagaaaa aataaataag aaatacgata atagagtgga attggattta
    16501 aaagactctt attacaatat gaaagaaaag attgagccag ttatgtttat agttgatata
    16561 gctaaagaag ctatggagga attaggtata aaaccacgtt tagttcctgt aagaggtggt
    16621 actgatggag caagattatc ttttaatgga ttaccttgtc caaatatatt tactggtgga
    16681 ttaaacttcc atgggaaaaa tgagtgtata ccagttagtt ctatggagaa agctactaaa
    16741 ctaattgtaa gaatagctga aaaatatgct gaaagagttt agttaaaagg tatttaaaaa
    16801 ttaagcattt aaagttataa tagctatatc attctttata agtcaagctg attataagct
    16861 tgtgttgtat ttaaaatggt atagctattt ttgtaattat ttttataaaa gataattatt
    16921 tttagtttag ggtatcaata aaaagtatga atatcaatag gtattaacat ttaaaagggg
    16981 gaattgtatt gaaaattaaa tctaaaaaaa taatagcatt tgcactttca cttgggatta
    17041 tgttgccaag ttgtgtatat gcagacacta ttagtaaaaa tcaaaatgca caggtagata
    17101 tgaacaatta tcttcaaggt agaaaatctc caaaggagga aaaacttatt ggtgaagata
    17161 gatttgatac agcgataaaa atatctcaaa gtggttggaa taatggttca gaaagggtgt
    17221 ttctagttaa ctcaaattca ttgccagatg cattggcttc aactcctttg gcaagtaaat
    17281 tggatgcacc aatactgctt acaaataaaa atagtatacc atataatgta atagaggaaa
    17341 taaaaaggct taatccagca gaagttattt taattggaag tgaaggagct atttcatcaa
    17401 gtgtaaaaga atctcttgaa gatatggaag tattagtcag tagaatcggt ggagcagata
    17461 gagaagaaac atctttactt cttactagac agctagatga tactggtgat ttaggtgtct
    17521 caaaagtggc agtggttaat gggtataatg gactggcaga tgcaacttca atatcaagcc
    17581 cagctgcaag tgataataca gctataatat atacaggtaa ggatagcata agaagtgagg
    17641 caaagaattt tattacacaa aactcaacta agacatacat agtaggtggg gagtacagta
    17701 taagtaaaaa acttgaagga cagttagtaa actcagaaag actagcaggg acagatagaa
    17761 aagatactaa tgcgaaagtt ttagaaaagt tttatggaaa atcaagtaag gttaataata
    17821 tgtattttgc aaaagatgga agtggtagag aagctgattt agttgatggg cttgctgctg
    17881 gagtattagc atcaaaaaca aagtcacctg tagtacttgc aagtggaagt ttaagtagtg
    17941 cacagaaaag ttttataaaa aaagtaaagg ctgataaatt tgtacaagtt ggtggaggta
    18001 aaaatagtaa accatatgca gaagcattag ccttacagta atattgtgta aatcaaaatt
    18061 aatatataat aatagcaagt aaaccaagtt gcacttcaat atatataata aaataagtaa
    18121 actaagttat atttcagtat aatatataat aaaataagta aactaagtta tatttcagta
    18181 taatatataa tgaaataagt aaactaagtt atatttcagt ataatatata atgaaataag
    18241 taaactaagt tatactccaa tataatatat aatagaaaca agtaaactaa gttatatttc
    18301 aatatagcat ataataaaac aagtaaacca gattctattt aattagaagt ttaaggtatt
    18361 gtacttaaac ttataattga gatagaaata aaatggttta cttgttttta ttatgaattt
    18421 aataaattaa agcttatttt atttttatta aaaatttact aatcattgat atttattata
    18481 tttccagtat tgatgtcaat taagtttata tcaagttcaa gctcatcctc atcatcagtt
    18541 tttatgatat ctataattgc gacagaatgg cttccatctt ttgggataga agtacttcct
    18601 ggatttatta ctattaaatt atcatccatg tatagttttt ttacatgagt atgtcctaaa
    18661 actaatatgt caccacccat tttctttgct ttgtcaataa tttcttcttc tgattctata
    18721 taaccatgat tcaatataat tctaatttca ccaaattggc tcatgacata aggactctga
    18781 ataggatgtt ctataaccat ctggtcaaca tctgcatcac agttcccttt tacaatcaca
    18841 atgttttcta atttatttaa tgtctcaata aattttttag gattatatcc ttctggaata
    18901 tcatttctag gtccatgata taagacatct ccaccatgta ataaaacatc acaatcagat
    18961 aatacattta acgctttttc aaagtaaagt aagctaccat gagtatcact cattattcct
    19021 attttcatat taaaaatcct cctaagtaca gtctataaaa atttttcaga tactctatgc
    19081 caaaactcat agtttgacat tctaagtaat tttatttttg catcagatat actaactttt
    19141 atattttcga tttgtctaaa tctgtgctca actccatcaa cgacaatcaa tacagaatct
    19201 tcaaatctat attctggtgc aatctttata acagattcat ttgaacatat tatacttgat
    19261 gtaaagcacc tatatgcatt ggtatttatc ggatgtaaag gtgtaatctg cataagttca
    19321 agatttatat caacaatact acctccagca gaatagttat aggctgttga acctgtggaa
    19381 gtagaaataa tcataccatc tccactaaaa ttttgtatat gtttattatc aaggcttaaa
    19441 tttaggtgta tagtcctaga cttgtctcct cttataacaa cctcatttac agcaagcata
    19501 ttagaaccac tagtagttgt atatacttcc gcattaagaa gtgacatttc ttgaataata
    19561 taatcttttt ttgtataagc ttcaataaag ctatcaatct tatctggtaa aatatcagga
    19621 aaaaacccca gatgacctgt atttattccc attatgggaa tttcaggaaa atcgaaatct
    19681 ctaactgttc ttaaaaaaga gccatcacca ccaattgata taataagctc tgtatctgga
    19741 taaatatctg aatacacttc aaagccagca ttgataagtt ttctagttaa gagttcttta
    19801 gtctcaaggg acttatttaa ttggtttgta tttatagtta taattctttt catatattca
    19861 cctcttcata ctttgtatta taacatagtt ttataattct taatttataa atttataaat
    19921 gacctttgta gtgaatgtgt taaaatatgt ataggtgggt ataaaaaaat gcataagagg
    19981 tgaagatgtg tttagcataa ggaatatcac aaaaaaatta ggaaaattca agttaaataa
    20041 tataaactta gagttaaagg aaggggatat tgttgggatt ataggaccaa atggttcggg
    20101 aaaaacgact ttaataaaaa ttataatggg gattattgat gcagatgaag gtgaaattga
    20161 actttgtaat gaaactattg aaaattctcc aataagcttt aaaaacaata ttggttttgt
    20221 atatgattct ttacaatttt atccgcattt aaaggttaag gaatttagaa aaatagtttc
    20281 tttattttat aagaattttg atagagaaag gtttgatgaa taccttaata agtttgatat
    20341 agaagaaaat atgcatattg aaaatttatc taaaggtcaa tctgagaagc ttatgttatc
    20401 aagcgcactt agtcataatg ctaagttatt gattttggat gaaccaactg ctggtataga
    20461 cccaattgta agaactgaaa taatgcagta cttacaagat tttgtgaaaa atggaagtag
    20521 tagtgtaata atttctactc ataatactga taatttaatt aaaattgctg attatcttgt
    20581 ttttataaat agaggaaatc agatttttac tgttaagaaa gaattaatag aacaagaata
    20641 taagataatt agggcaaata aagcagagtt agaagcaatt aaagaaagca tagttggtgt
    20701 gaaagagtat aaatattata atgaggcact tgttaaagtt ggagatagct tgaaagtaaa
    20761 aagcctattg atagaaattg ataagcataa ggtcaaaaat cctactatag aagaactaat
    20821 gtattattat gtaaatgagg tgagatgatg ttcaatttaa taagaaaaga tttaataata
    20881 gggattagtt cagatggtat ccgtaattta aagtacatat tgctattttt tgtgttttat
    20941 tttttcctta attcaatttc atattataca gtaagtattg ttgttagtta tttgatattt
    21001 ataaatacat ttgagtgtga ttatgaaaat gattcaagga tttttataag gagtatgcca
    21061 gttagtatag aagatatagt ttactcaaaa tatttattag gtgtaggatt aataatttct
    21121 gtaacaataa ttgtgtcctt actaagtaaa ttgacatcac tagtgttctt tagaaatatg
    21181 gttttaaatg atgtattttt ttctgtaaat atatttttag caattttgac gattttactg
    21241 cctttaattt ttaagtttgg atatggaaaa atgaaagttt gtggttttat agtaagtatt
    21301 ttaatttact ttgtatatgg aagtcttttg aagatgatta gtatgattgt atatcaagta
    21361 aagcatttta attatagtaa agttggagga gtatatcttt caaattatgt aactgatata
    21421 gctaatacta agtatataaa tttatatagt atgacatttt taacaataat aatttttata
    21481 atatcaatgt atttttctat taagatttca aaaaagaata agtttaatta ttaaaatttt
    21541 gattaatatt atagcacaat agcacaaaat ataaggagac taaaaatgaa gaagtttata
    21601 aaagtttcat tttttatttt ggggattttt acactattca tagctataaa taaattagta
    21661 tatagagata tggtaagtgt caaagattat gaaataaatc atttagagga aattgttttt
    21721 gattttgata gcaggagaag tagagatgtt ggtactattg taagatttaa aataagcaat
    21781 aatagtaaat atagttataa attaaacagt gctaaaatga agtttgaaaa ttgtgtggaa
    21841 aataaaaagg gaatgaataa gtgttctgca tatgtaaatg tagatttatt taatgaaaaa
    21901 aattctataa ctgaaagaac tctgaaatat ggaataaaac caaataatca aggttatgtt
    21961 gattttgtaa ttccaaaagg actaaatttt gattataggt actttaatga atctggtatg
    22021 agtgtagagt ataaaggaga atatattgtc aatattccaa tggcaaaagg actttatcta
    22081 gtagttggaa aaaataatga tacatggaat gctaatatta tggaataatt tgaaaaataa
    22141 atcaattata gatataatta agaataatat gaaatttata aaagttcaga ctaggagggg
    22201 tatttaatgt caataagtaa tgtaagagag tattttaaac aatttggcaa ggaagacagt
    22261 atattagaat ttgaacaatc tagtgctact gtggaacttg cagctgaagc agctggggtt
    22321 attccagcaa gaatagctaa gacactctca tttaaaatag gagatgatgc aattttaatt
    22381 gtgacagctg gtgatgctaa gattgataat aagaagtata aggctgaatt taattgtaag
    22441 gctaaaatgt tgacaccaga agaagtcttg gagtttactg gacatgctat tggtggagtc
    22501 tgtccatttg gtttaaaaaa ttctataaaa gtctatttag atgattcaat gaaaagattt
    22561 gatacagtat ttcctgcatg tggcagtagt aactctgcaa tagaacttac atgtgaagaa
    22621 atggagaagt tttctaagtg tgaaaaatgg gtagatgttt gtaagaattg gtaaaaaaat
    22681 atagtaaact atagtaggaa ttagtaaaaa actacctctg tatacaatct atacagaggt
    22741 agtttttttg tgtaaatatt tataaatcta agaggaaaat ctaatttaaa ctaataatcc
    22801 aaaataaagt taaaaaattc tgattttttt tcgaaacaat aaaaaaatga caaaaaagtg
    22861 gaaaaaatgt aataaatatt gttaaaaaaa taattagaaa ttattgaaaa attatccttt
    22921 gagtgatact attatagatg taagatattt aaaaataaaa aatagtcaga taaaaatatg
    22981 attatttagc tctattaaaa taatttttat acgataaaaa tcttctgtac atggctaaaa
    23041 aacagatgta cagacaatat ttaatgttta atatacccta atataaatat cgtaaacaaa
    23101 ttattttatc tctaaccagt gtgaaagaaa tcttattcta acttgaaatt tcacaaaatt
    23161 ccaaaaagcg agattttttt taagtatagt tgattttaaa ttaacaattt atgattaaat
    23221 taatgtcata attggttagt ataatcacat ataaatatag agcgtagttt gattaaggtt
    23281 ataaatttct cgacgtatat tcaaatacct tattatagat gttgccgaga ttttaattaa
    23341 taaatgaaaa taaaatattt ataaaatact gaggaggcta ttatggattt aaattctaaa
    23401 aaatatcaga tgcttaaaga gctatatgta agcttcgctg aaaatgaagt taaaccttta
    23461 gcaacagaac ttgatgaaga agaaagattt ccttatgaaa cagtggaaaa aatggcaaaa
    23521 gcaggaatga tgggtatacc atatccaaaa gaatatggtg gagaaggtgg agacactgta
    23581 ggatatataa tggcagttga agaattgtct agagtttgtg gtactacagg agttatatta
    23641 tcagctcata catctcttgg ctcatggcct atatatcaat atggtaatga agaacaaaaa
    23701 caaaaattct taagaccact agcaagtgga gaaaaattag gagcatttgg tcttactgag
    23761 cctaatgctg gtacagatgc gtctggccaa caaacaactg ctgttttaga cggggatgaa
    23821 tacatactta atggctcaaa aatatttata acaaacgcaa tagctggtga catatatgta
    23881 gtaatggcaa tgactgataa atctaagggg aacaaaggaa tatcagcatt tatagttgaa
    23941 aaaggaactc ctgggtttag ctttggagtt aaagaaaaga aaatgggtat aagaggttca
    24001 gctacgagtg aattaatatt tgaggattgc agaataccta aagaaaattt acttggaaaa
    24061 gaaggtcaag gatttaagat agcaatgtct actcttgatg gtggtagaat tggtatagct
    24121 gcacaagctt taggtttagc acaaggtgct cttgatgaaa ctgttaaata tgtaaaagaa
    24181 agagtacaat ttggtagacc attatcaaaa ttccaaaata cacaattcca attagctgat
    24241 atggaagtta aggtacaagc ggctagacac cttgtatatc aagcagctat aaataaagac
    24301 ttaggaaaac cttatggagt agaagcagca atggcaaaat tatttgcagc tgaaacagct
    24361 atggaagtta ctacaaaagc tgtacaactt catggaggat atggatacac tcgtgactat
    24421 ccagtagaaa gaatgatgag agatgctaag ataactgaaa tatatgaagg aactagtgaa
    24481 gttcaaagaa tggttatttc aggaaaatta ttaaaataga taaatattaa aatatacaca
    24541 ataggtcgat attaaaatag atatggagga aggatttatg aatatagtcg tttgtataaa
    24601 acaagttcca gatacaacag aagttaaact agatcctaat acaggtactt taattagaga
    24661 tggagtacca agtataataa accctgatga taaagcaggt ttagaagaag ctataaaatt
    24721 aaaagaagaa atgggtgctc atgtaactgt tataacaatg ggacctcctc aagcagatat
    24781 ggctttaaaa gaagctttag caatgggtgc agatagaggt atattattaa cagatagagc
    24841 atttgcaggt gctgatactt gggcaacttc atcagcatta gcaggagcat taaaaaatat
    24901 agattttgat attataatag ctggaagaca ggcgatagat ggagatactg cacaagttgg
    24961 acctcaaata gctgaacatt taaatcttcc atcaataaca tatgctgaag aaataaaaac
    25021 tgaaggtgaa tatgtattag taaaaagaca atttgaagat tgttgccatg acttaaaagt
    25081 taaaatgcca tgccttataa caactcttaa agatatgaac acaccaagat acatgaaagt
    25141 tggaagaata tatgatgctt tcgaaaatga tgtagtagaa acatggactg taaaagatat
    25201 agaagttgac ccttctaatt taggtcttaa aggttctcca actagtgtat ttaaatcatt
    25261 tacaaaatca gttaaaccag ctggtacaat atacaatgaa gatgcgaaaa catcagctgg
    25321 aattatcata gataaattaa aagagaagta tatcatataa tttaaggggg gataaagaat
    25381 gggtaacgtt ttagtagtaa tagaacaaag agaaaatgta attcaaactg tttctttaga
    25441 attactagga aaggctacag aaatagcaaa agattatgat acaaaagttt ctgcattact
    25501 tttaggtagt aaggtagaag gtttaataga tacattagca cactatggtg cagatgaggt
    25561 aatagtagta gatgatgaag ctttagcagt gtatacaact gaaccatata caaaagcagc
    25621 ttatgaagca ataaaagcag ctgaccctat agttgtatta tttggtgcaa cttcaatagg
    25681 tagagattta gctcctagag tttctgctag aatacataca ggtcttactg ctgactgtac
    25741 aggtcttgca gtagctgaag atacaaaatt attattaatg acaagacctg cctttggtgg
    25801 aaatataatg gcaacaatag tttgtaaaga tttcagacct caaatgtcta cagttagacc
    25861 aggggttatg aagaaaaatg aacctgatga aactaaagaa gctgtaatta accgtttcaa
    25921 ggtagaattt aatgatgctg ataaattagt tcaagttgta caagtaataa aagaagctaa
    25981 aaaacaagtt aaaatagaag atgctaagat attagtttct gctggacgtg gaatgggtgg
    26041 aaaagaaaac ttagacatac tttatgaatt agctgaaatt ataggtggag aagtttctgg
    26101 ttctcgtgcc actatagatg caggttggtt agataaagca agacaagttg gtcaaactgg
    26161 taaaactgta agaccagacc tttatatagc atgtggtata tctggagcaa tacaacatat
    26221 agctggtatg gaagatgctg agtttatagt tgctataaat aaaaatccag aagctccaat
    26281 atttaaatat gctgatgttg gtatagttgg agatgttcat aaagtgcttc cagaacttat
    26341 cagtcagtta agtgttgcaa aagaaaaagg tgaagtttta gctaactaat ttcttgggga
    26401 gggtattatg agtacaagtg atgttaaagt ttatgagaat gtagctgttg aagtagatgg
    26461 aaatatatgt acagtgaaaa tgaatagacc taaagccctt aatgcaataa attcaaagac
    26521 tttagaagaa ctttatgaag tatttgtaga tattaataat gatgaaacta ttgatgttgt
    26581 aatattgaca ggggaaggaa aggcatttgt agctggagca gatattgcat acatgaaaga
    26641 tttagatgct gtagctgcta aagattttag tatcttagga gcaaaagctt ttggagaaat
    26701 agaaaatagt aaaaaagtag tgatagctgc tgtaaacgga tttgctttag gtggaggatg
    26761 tgaacttgca atggcatgtg atataagaat tgcatctgct aaagctaaat ttggtcagcc
    26821 agaagtaact cttggaataa ctccaggata tggaggaact caaaggctta caagattggt
    26881 tggaatggca aaagcaaaag aattaatctt tacaggtcaa gttataaaag ctgatgaagc
    26941 tgaaaaaata gggctagtaa atagagtcgt tgagccagac attttaatag aagaagttga
    27001 gaaattagct aagataatag ctaaaaatgc tcagcttgca gttagatact ctaaagaagc
    27061 aatacaactt ggtgctcaaa ctgatataaa tactggaata gatatagaat ctaatttatt
    27121 tggtctttgt ttttcaacta aagaccaaaa agaaggaatg tcagctttcg ttgaaaagag
    27181 agaagctaac tttataaaag ggtaaaaatc taattaaaaa tatatttgct gttaactaga
    27241 ttaaatagta ttttaatcta gttaacagaa tataaatact aaaataacag gaggttataa
    27301 ctatgaaatt agctgtaata ggtagtggaa ctatgggaag tggtattgta caaacttttg
    27361 caagttgtgg acatgatgta tgtttaaaga gtagaactca aggtgctata gataaatgtt
    27421 tagctttatt agataaaaat ttaactaagt tagttactaa gggaaaaatg gatgaagcta
    27481 caaaagcaga aatattaagt catgttagtt caactactaa ctatgaagat ttaaaagata
    27541 tggatttaat aatagaagca tctgtagaag acatgaatat aaagaaagat gttttcaagt
    27601 tactagatga attatgtaaa gaagatacta tcttggcaac aaatacttca tcattatcta
    27661 taacagaaat agcttcttct actaagagac cagataaagt tataggaatg catttcttta
    27721 atccagttcc tatgatgaaa ttagttgaag ttataagtgg tcagttaaca tcaaaagtta
    27781 cttttgatac agtatttgaa ttatctaaga gtatcaataa agtaccagta gatgtatctg
    27841 aatctcctgg atttgtagta aatagaatac ttatacctat gataaatgaa gctgttggta
    27901 tatatgcaga tggtgttgca agtaaagaag aaatagatga agctatgaaa ttaggagcaa
    27961 accatccaat gggaccacta gcattaggtg atttaattgg attagatgtt gttttagcta
    28021 taatgaacgt tttatatact gagtttggag atactaaata tagacctcat ccacttttag
    28081 ctaaaatggt tagagctaat caattaggaa gaaaaactaa gataggattc tatgattata
    28141 ataaataaga atttgggaat taaaagttta aataaaattg tttaaaaaac aatttcggat
    28201 atatgaaaaa tctaatttaa tgggggtaat gaatatgaga gaagtagtaa ttgccagtgc
    28261 agctagaaca gcagtaggaa gttttggagg agcatttaaa tcagtttcag cggtagagtt
    28321 aggggtaaca gcagctaaag aagctataaa aagagctaac ataactccag atatgataga
    28381 tgaatctctt ttagggggag tacttacagc aggtcttgga caaaatatag caagacaaat
    28441 agcattagga gcaggaatac cagtagaaaa accagctatg actataaata tagtttgtgg
    28501 ttctggatta agatctgttt caatggcatc tcaacttata gcattaggtg atgctgatat
    28561 aatgttagtt ggtggagctg aaaacatgag tatgtctcct tatttagtac caagtgcgag
    28621 atatggtgca agaatgggtg atgctgcttt tgttgattca atgataaaag atggattatc
    28681 agacatattt aataactatc acatgggtat tactgctgaa aacatagcag agcaatggaa
    28741 tataactaga gaagaacaag atgaattagc tcttgcaagt caaaataaag ctgaaaaagc
    28801 tcaagctgaa ggaaaatttg atgaagaaat agttcctgtt gttataaaag gaagaaaagg
    28861 tgacactgta gtagataaag atgaatatat taagcctggc actacaatgg agaaacttgc
    28921 taagttaaga cctgcattta aaaaagatgg aacagttact gctggtaatg catcaggaat
    28981 aaatgatggt gctgctatgc tagtagtaat ggctaaagaa aaagctgaag aactaggaat
    29041 agagcctctt gcaactatag tttcttatgg aacagctggt gttgacccta aaataatggg
    29101 atatggacca gttccagcaa ctaaaaaagc tttagaagct gctaatatga ctattgaaga
    29161 tatagattta gttgaagcta atgaggcatt tgctgcccaa tctgtagctg taataagaga
    29221 cttaaatata gatatgaata aagttaatgt taatggtgga gcaatagcta taggacatcc
    29281 aataggatgc tcaggagcaa gaatacttac tacactttta tatgaaatga agagaagaga
    29341 tgctaaaact ggtcttgcta cactttgtat aggtggagga atgggaacta ctttaatagt
    29401 taagagatag ttttagatta taatatttac aaattaaata tttaattatg aatttaacct
    29461 gtaagaataa ctatttgtta ttcttacagg tttttatagt taaaaataat tattatctat
    29521 taaacaaaaa tagtgtaaaa tatataatat catgattttg aagatataaa aagtaggaag
    29581 atataaaaga aagtaggtaa aagtttgttt aaaaaagaga atcaaagata taatcttata
    29641 tcgtatacaa atgaagaaga aatgacttta aaagaagttt tattggacaa gctaaatttc
    29701 tcagttaggt cattatcaaa aatgaagagg gaaaagagtg ttttagtaaa tggagtatat
    29761 aaaaaaccaa gtttaaaggt gtatagtggt gatttaatag aagtaaaaat agacgaggaa
    29821 aaagcaaatt ttgaacctca agatttaaat ttacagataa tttatgatga ttttgatata
    29881 attatggtga ataaacctcc gtttatggta gttcacccaa caaaaagcca ctatgataaa
    29941 acaatagcaa atggtattag ttactatata gataatcaaa aagaaaacgt aaaaataaga
    30001 tttgtaaata ggttagatat gaatacttca gggttagtta tagtagcaaa aaatgcttat
    30061 gcacatcata ctttgtctac agcaatgagt gaaaataaag ttgaaaaaaa gtatataaca
    30121 gtagttgatg gaattataaa agaaaatgag ggaactatag atgagccaat ttatagacct
    30181 acagaagatt caataaagag gataatagat gaaagaggac agtcatctgt tactcactat
    30241 aaagtaatag aaagactaga aaatgcaact gtattagaag taagcttaga aactggtaga
    30301 acacatcaaa taagagtaca tatggctcat ataggtcatg gaataatagg tgatgagttg
    30361 tatggttatg tagatgaaga gctaataaat aggcaagcac ttcatgcata taagctagag
    30421 tttgaacaac caagaacaaa agaaaaattg aaatttaaag cagatatacc agaggatatg
    30481 aaagagttaa tatcgaaatt aagataatgg ggtgatatat atgataatac ataaatttat
    30541 aatacatgtt ttggacaaaa atagtgatgt tccaatatta aatgactttg aaggcaaagt
    30601 taatcaagaa gtggatggtt ttttccagaa agctataaaa agaattgcaa aagatgagga
    30661 tttaagaaaa ggtgttttta aagattataa tgacaattta attaaaaact gttgtgaaca
    30721 aataatatat gatgaaagta cttttttgaa aaattctaaa gaaattgcat cttacttgtt
    30781 tgacgttatg aaaattaatg ctgcactaga atcttgtgat ttggcaattt gtttatacac
    30841 tattaaagat gaaaagagtg tagcaatact gaaattagat tataaaaagt tgtacactca
    30901 ttcaattgaa tttgtggatg ataaatttaa tattcaaatg gtttcaaatg aaattggtat
    30961 cccagagact ttaagacaaa agcaaggagc tttgattagt ctaagtggta taaatgatga
    31021 gtttcatcta aggcttttag ataaggatgc tgaaaaagaa gggtcagaat ctaagtttgt
    31081 aacagaattt ttaaatgcta aaaaaataga tgatgataag tacaagacca aggtatttaa
    31141 aaatacagct gaaaattgga taaccaatgc tcttagtaat gatataaagc aagctgaaga
    31201 tgtaagaagt atattaaatt atacactgaa ggaaaaacat gaagttgata taaatgactt
    31261 tgttgataat tcaattaaag atgatgagtt aaaggatagc tttaaagagc atatggaaga
    31321 aaaaggtctt gacgaaagtt ttagtataga taaaaaatgg gttgagaaaa agcttaaaaa
    31381 aagaagtata aaaacggata atggttttga cataaaaggg aatctaactg attttgaaga
    31441 cccaatgaag tatactgtaa aacaaaatca agatggaact atagatataa taataaagaa
    31501 tgttacgttt tatgaagaaa agtaatttat atacttagta tataaattaa atataagagc
    31561 gtgtatttta tatattgtaa ataaatgtaa tctagtctgt gcgaactcta atataattta
    31621 ttatgtagaa gtttacacag actatttata tttgtagaca aaacgatact atttgttttc
    31681 ttcgatatat ttacatatat caccaataca tttaaagttt tcagcttcct cgtctggtat
    31741 ttctattcca aattcatctt caagggccat tataatttca acagcatcta atgaatcagc
    31801 ttctaagtcg tccattaaag atgcttccat agttatctca tctaaattgt ctacccctaa
    31861 ttgttctgct attatttctt ttattttctc aaacatttta agcctcctaa agcagtttta
    31921 attaatttta atgttagttt aatataatat caagaatttt tcaatatgga atctataaaa
    31981 aataataaaa ttttataaat gtagtaataa agtattattt gatgaataaa ctttattgat
    32041 aacaaatata acttaggagg aaatgctatg aaatatgtag gactattact aacttcagta
    32101 ggaatgtttt tacttatagc agtaaatttt tattataatt caataacttt agatatgcaa
    32161 cgtatagagg attatgtaat ggagaccaat ttaatccttg aagatgtagc tgaaaaggag
    32221 agttatgtat ctaatgaaaa agaagattac atatcaaggt taatgcatgt aaagaaagga
    32281 atagaaaatt caaaaacatc cttcttgata gaaagatata aggagtacaa aataaaatca
    32341 atagaaagtt taatctatac tatatcagag gagaaaaaag attatctgga tgaagttgat
    32401 agatacaata aacttggtga aaaagaaata aataaactaa tcaataaaaa ctttttagaa
    32461 gtaacttatc tgtctattac tacatatatt taattaaaga gacaaaactt agtctcttaa
    32521 tgattcaagg aggattagtt atgacaaaat tagaagacaa tatggaacgt ttctttggag
    32581 gatgcgaagg attttttggg aataaaatgt tgataataat agttatagta ttcttactat
    32641 tatgcacaga cattttagaa gacttattat gcgatgacaa tatatggata tgggttatat
    32701 taatagtatt gttattattt aacttcgatg atggttgttg ttgctaaaaa atattgatta
    32761 ttaaataggt aaaaccagta acttatacaa gttatggttt tacctttttt agttcaaatt
    32821 aaaaaattta aaaaaatagt aaaaatacat tagcaaaatg gaaaccaaat gcatagtata
    32881 tgttaggagc gaaaagctca acaaaatatc aacaggaggt aacgtataat gttagataga
    32941 ttctttggag aagaaggatg ttttggtgga ggaggatggt ggataatagt actattcttc
    33001 ctattcttag cttttggaga tagctgggca gaatttgaca taatggcatg gataccattc
    33061 ctaatagttt tattaatact ttgctgctgt ggtggatgct tagaataaga acacagttat
    33121 taaaaaaagg agggctttgt tatgttagat agattttttg gagaagaagg atgctttggt
    33181 ggaggaggat ggtggataat agtactattc ttcctattct tagcttttga agattgctgg
    33241 agagacattg acataatgtc atggatacct ttcttaatat tattgctaat aacttgttca
    33301 tgtggtggat tctttgatgg tgaagtaggt tgcggctgct aatacttaaa tcattagaat
    33361 aaaaaaatgc tggtatttta taccagcatt tttttatttt attttttaat atgatttaaa
    33421 ttaagaatga atattattaa atttgttgaa tatagggtat aatataaaat ataatgtatt
    33481 taaatgtact tgcttttatg gtaaaataaa aacttatata aatgtagtta aaataggaac
    33541 cttcaaaaat ttggttcagt tttagataaa tttagtaaaa taaggaggat gaagatgaaa
    33601 ggcaatataa cgataaaaga tgttgctaaa caagcaggag tgtcaatatc tactgtatct
    33661 agagttataa atgattcaaa acctgtaact gatgaagtca aacaaaaagt tttagaggtt
    33721 ataaaagaga ctggatatat accaaatcca cttgctagaa gcttagtaac aaagaagagt
    33781 caattaatag gggtaatagt tccagaagtt tcagattctt ttgttaatga ggtgttaaat
    33841 gggatagaag aggttgctaa aatgtatgac tatgatattc ttttagcgaa tacatactct
    33901 gataaggaac aagaacttaa gagtataaat ctattgagag caaaacaagt ggaaggtata
    33961 gttatgattt catggatagt tgaacaagaa catatcaact atatacaaaa ttgtggaata
    34021 ccagcgacat atataagtaa aactgctaga aattatgata tatatacagt aagtactagc
    34081 aacgaagaag ctacttttga tatgacagag catcttataa agaaaggtca tgaaaagata
    34141 gcttttataa tgactagtaa agatgatact gttttagaaa tggaaagact tgctggttat
    34201 gagaaagcac tttcaaataa caatatagaa ttagacaaga gtttgattaa gtatggtgga
    34261 actgattatg agagtggata caatagtatg aaagaactat tagatgatgg aataatacct
    34321 catgcggctt ttgtaacagg tgatgaggct gccataggtg ctataaatgc tatatgtgat
    34381 gctggatata aggttccaga agacatatca gttgcaggat ttaatgatgt taagatagct
    34441 agaatgtata gacctaaact tactacagta tatcaacctc tatacgatat gggagcagta
    34501 gcaataagaa tggttataaa attaataaat aaggaattaa ttgaaaataa gaaaatagag
    34561 ttaccttata gaattgttga tagagaaagt gttacagaaa gaaaaaaata aaactattaa
    34621 aatcaatcag gtagtgcctt aggcactacc tgatttttta tgtcaataat atcaaattta
    34681 ataatagatt aactaaaaat aattatctaa ttgcttaaat agtttatttt tatctattca
    34741 tgaggattag actttttagt tttcttaaat aaacttttag attttttttg ttgactacct
    34801 ggtgtatttt ttggtgcagg tgaatttgac ttacctttag taggtttagc cttcttagtt
    34861 ttagctggtt tagtatctct ttggttttct gcatctgaga ttttttccat tatattatcc
    34921 agttttttgc gttgattttc atctaaaaat gctttgaatt ttgatactac ttcatctctg
    34981 ccatctagat tcttacctat ttttataagt tcctccataa gttcattttc tgattttcct
    35041 ttgtaactat cagccatctt ttctatttta tccttgtcaa tatttttttg tttagccatt
    35101 ttttctaatg actctgtatc taattttttc ataaaaaaac ccctttctat aaatatatat
    35161 tgaattatat tcatactatt tatatataga aataatattg aagtggtgaa ttgtgagtga
    35221 tatataatat aaataaaaat tcttatagat aatatatatg cactgagctt taaaaatgga
    35281 acattaaaat atgaaaaaca tactttaata tagggcaatt atataatata agggggaatt
    35341 gtcttgaata acttactatt tttgattgga gtgattgcat tgagtaatgg taatatctct
    35401 atatttgatg ataaaaataa atcaaaagga aataatagag ttagaaaaaa caaaaaaaat
    35461 gcaaatgata aactttcaca gtctacacat ggcaatttaa ggtttgatgc aaatgatata
    35521 aaaagaggtt taaggctcat ggatttaagt gaagaagatt tagaaatggg aatggaaata
    35581 ataacaagaa ctaaaaaata catgtcaaga gatgaaagaa aaatactaat aaaaatagaa
    35641 agtgttttag atttagttag aggaataaaa aaattaaata atatagatat ggtagataca
    35701 gaagatgaaa cggatttttt cagaaaaatg gatagtgatg ataaaaagaa tatgatgata
    35761 aaggaaatta tagatgtatt cccagaaaaa agaaaaaatt cagttgaaaa agctatagga
    35821 atgaaaaaga agatagattt atttgcagaa ttatttttac cagatgactt tggtgaaggt
    35881 ggatttagtt tgagctcttt ggcaaatata aacaatcttg gtagtatgaa taatctcaaa
    35941 ttgttaggaa gtcttttaag aggtgatgat agtaataatg atgatgaaga caataatgat
    36001 gagttaaatt atgaagacga agaattagat tgtgaagaca aagaattgga tgatgatgag
    36061 ttaacagatg aaggtgaaat ggaggataat gaagatgaat tagtagaaga taagaacaca
    36121 ggctatgaaa atatagaaaa tgatgaagat atagtatacg atgaggaact atacaacatt
    36181 aatgagcaag aatccgaata caattataat gaaaaaaata ctaaaactag agctaagaaa
    36241 aaacgataat taactaaata cataaagaaa aaaggaagaa aaagtaatga tagaataaga
    36301 ttatctcaat tactatataa aaccacttta aaaaattcaa aatttattat ataataataa
    36361 tatgaaatcc tgaaacatac gataaggctt ttttaaattc aacctacaaa tgaaatacgg
    36421 gagaccgtgt ctggtaaatt ataacatgcc tagttagttt ggacgttaaa ggttactggc
    36481 aagtcaccca cctgggagtg cctagggtgt gaatttactt agccaccggt gtttcgggac
    36541 aaaaaaagtg ctactatttc aaatagtagt acttttttta ttaatatgca tttttctact
    36601 aaatacgcct aattattgat aaattcaaaa agcaagtaac aattaagatt ataaaagcat
    36661 agtattaatt aggcttcaaa aagccaaaga cttaataaga atcgcttaca gggagggcaa
    36721 tgaaaaatgc aagattataa aaaaaataaa agaagaatga tgaatcagcc aatgtctaca
    36781 atgaatgaag aagaagtgta tacagatgaa ataaattcag aagacatgag aggttttaaa
    36841 aaatcacacc atcataatgg atgtaatact gataataagt gtgagtgcca tgatgattgc
    36901 aatccatgca acccatgtaa tccatgtaaa cctaacccat gcaatccatg caaacctaat
    36961 ccatgtgatg acaattgtgg atgccatgac aattgtaaat gtgattgtga accatgtgaa
    37021 atggattcag atgaatgttt tgaaaacaaa tgtggaccag aatgctgtaa tcctatatct
    37081 ccaagaaact tctctgtatc aaatgcagtg ccatttgcaa tagaggctaa tagaatattt
    37141 gatactatgc aattccaaac atttacagat gcaacaggac caaatggaga gccattaact
    37201 tttgaaacag aagtagtaga agtatttggt tcagttccaa gtgcaggtca agcaagtgta
    37261 actatagaaa aaatatgctt aagtaatgat ggaatcgtta tagacacagg aatgacaact
    37321 ttagaagatt tcgatttaga cccattagga gatatagtag gaagaaactg tgaaacaact
    37381 tttgaatttg cagtttgtgg agaaagaaac tctgagtgct gtagacaagg aaaaggcaaa
    37441 tcagtagctt ataaacaaag aggattaact gtagcagttc gtaatttagt actagagcta
    37501 agaggtagat gtggatgtac agagttcgtt gcattagctt tcccagcagt tagagcagga
    37561 ggtggatgta agagaagagt tgattatgta gaatttactt ttaacacact ttcagcacca
    37621 atatgcttgc cagctgacgg aagagctgtt actttaagac aagaatatca aactaactta
    37681 actgtagatt gtataggaaa atctatatta aaattagaat gcaacgaatg ttgtgaacct
    37741 ttctatgaat taattatacc aaatgatata gatttagtac tttgcttaca agaaacagtt
    37801 agcacattaa taagtgaaca aatagtagtt ttagcatcac caaatccaat ccaaccaaga
    37861 cttgttgata ctttctctaa agtatgtgat ttttcgcaat gtggacctaa tcatggaagt
    37921 ggaaagccaa gttgccacag atagataggt agatatatag acagtttaaa ttataaataa
    37981 aaatcatcta aggaaggcta ccaaagtgta taatttacat tggtagcctt cacgttttta
    38041 taactagcgt atagatttta gtgatttaaa aagcactata gtatgtaata gacaagtaaa
    38101 gattgatact atcgtcattg tgtatatgta tgcataaata ttaagtcctg gaattggaag
    38161 aaatacatat aaagctatta gttgaattaa catgccagta atagtattta tacttgaagc
    38221 taattctttt cttattgaat gtaaaatgcc agatagagtt tgatttaggg acataaatag
    38281 tggaactaaa aacatagctt ttagatattc tcctgcaagt gtatttttaa atactaatat
    38341 acataaatct tttccaaaga aataaaaaaa tattgatgat agtatgccta caaataaagt
    38401 aagaagtatg gagtatttga tttttttaat tacactctta cgctttctta gagccatttc
    38461 ttgtgaaata gttggtatta aatttacaat aagcgctgaa ccaacagtaa aaggtaaaaa
    38521 tataaaaggc attaccatcc cactgacaat accatacata cttaaagatt gttgataagt
    38581 cattcctgat aatgctaatc ttgatggtat catcatagaa cttatagatt gcaaaagtat
    38641 gtttgacatt ctattacaag ttatgggaat agacattttt aatgtttcca tagaagaatt
    38701 ataaaaatct tttatgctta taatatacct attgtcaaat gatgaatctc gccataagca
    38761 aataagcata aatataatat tactcaactc accaatcgat atacctaata gagctatata
    38821 acaattcata gatttattat ttatgtacat aacaagtaaa aaaacaaata atattttacc
    38881 aatttgttca atgatttgtc caatagcagg gatttttaca ttctttatgc catagtaata
    38941 tcctcttagt acgtttgaaa gagttattat aactatagca ggacaaacag ctagtataaa
    39001 tagatttaat ttagcatctt ttaaaaattt aagtgataaa aaagaactat tgaaagatgc
    39061 aactatagat ataattagtg ctacgaaaaa tgatatatat aaagttgata taaataaagc
    39121 attagtattg tgtctatcgt ttaaagcttt tctctttgca actagacaac taagtgcagt
    39181 aggtatacct gttgttgtaa cagctaagca aatcatcaaa aagttaaaaa tcatatgata
    39241 gatacctaaa cctgtttcac ctagtgctct tgataagaat attttatata aaaaaccaaa
    39301 tattcttaca ataaaattgg atataaataa aataactgtt gatagtacta aataaggtac
    39361 tttcaaaaaa atcacctcct tatcttttaa atatattcac aaggaggtgt aaaaatttat
    39421 aattttataa attctggttt caatttatta aatttagata catatttaaa tcccatattt
    39481 tttagtaatg aatatatgta gtcaaactca catgcaactt gacttatatg atgtgaatct
    39541 gaacctgtgg ttatgatttc ccctcccaag tctttgtaca tttgaagtat atacttagat
    39601 ggggttaggt ctggaagatt atatctataa caagaggtat ttatctcgat acctttgcca
    39661 tcataaatag cttgtttaag agtttcttca attatatcag aaaatagtct atcatctaaa
    39721 atagtgtcat aaggtgcata ccttttaatc aaatctaaat gacctaagac agagtaatct
    39781 ttataattct taacaatatt atataaataa agatagtaat tttcataaac ttcatgttga
    39841 gttttatctt taaaataatt accaaggtat aagtccattg tatctatagc atggatagaa
    39901 catattataa agtccaatgg atattgatgt gcttcctttt tgtatgtatc cattaattga
    39961 gtttgaactc caaattcaat tccttttttt attgatattt tatctttata tttgctttga
    40021 agagtctcta aactcttaaa ataatcttcg tagacaattg aaaaagaatc atcagcatat
    40081 acatcatagt caacatggtc tgtgaaacaa atttcctcca aaccgagttc aatagatttt
    40141 tttaccattt cttccattgt agattttccg tctgtagaga aacttgagtg catgtgatag
    40201 tcgtaaaaca taaatatttc ccctttttat aaaaattttg gtattatata tacatactaa
    40261 ataatatcaa atatacataa aagcatcaat aaaatataaa tacaatgagc ggtgataaat
    40321 ttggaaaaat acagaataga tttaaatgag aaaaaatcaa ctaaatatat acagatattt
    40381 aatcatataa aagaattgat aataaataaa gagttagtag aacatgaaaa attgcctcca
    40441 ataagaaaac tatcaaattt tttacaagta aataacacta ctatagttaa ggtatacgag
    40501 cttttagaaa atgaaggata tgtatataaa attataggga gtggtacttt tgtatcaagt
    40561 ttaaattctt ataaaagcgg tatagataac aggaaaaata agattattgt gcaaagagaa
    40621 gatttaattc attttgacaa tgggaatcca tctaatgata tgtttcctat cgattcattt
    40681 aaaaatgctg taaatatggc attatctaaa gatggtagtt caatatttga atatgatgaa
    40741 ggtcttggct ctgaagaatt aagagaaaaa atggtagagt atctaagtga tggaaatata
    40801 aaaactacta aggaaaatat tcaaataata tcaggtgctc aacaaggtat agatatagtt
    40861 tgtaaaggac ttataagtta ttcagatgtt gtttttatgg aagaaccttc ttacaatgga
    40921 gcaattgaag tgtttaaaag tagaggtgca aaaataatat ctatacctat gttagatgat
    40981 ggaattgata taggtatttt aaaattaaag ttggaaaaaa taaaaccaag acttatatac
    41041 attatgccta attttcaaaa tccaactgga atatcttact caacatataa aaaaaagaaa
    41101 ttgatagaat tggcagaaga acatgatttt tatataatag aagatgattt tataagtgat
    41161 tttgtttttg aatcaaagga caatagaaca attagaagtt atgatgataa aaatagagta
    41221 gtatatataa aaagcttttc aaaaatactt atgccaggtc ttaggatagg aattgtagaa
    41281 atgccaaatg agttgttaaa aaaagtttta tgggctaaat attcatcaga tatatcaaca
    41341 ccaggtttaa ttcaaaaatc aatgtattac tatatgaata attttgattg gaagaattat
    41401 ttgagtcata tagagaagat atatactgat aagtataaat tggcaaaaaa cttgattaat
    41461 gacaaattga gtggtaaatt aaaagttaga aaatcttgtg gaggaataaa ctttttttta
    41521 gaattaccaa gaggatatac atctcaagca tttacaaatt ttatgttaaa caaaggagtg
    41581 tcaatgcttc cagggactta tttttttgac aatctagtgg atgatagatt ctttaggata
    41641 aatatagctc gtccaagcat ggaagaacta gaaaagggaa tatctataat aagtgataat
    41701 atagatgagt ttttttgtga atataaaaac aagttagata taaaaagcaa taaattattt
    41761 tattaaataa atagaggttt tttaggagga aaaaatgttt gacaagaaga aattagatag
    41821 gattaatgaa ttagcaaaga aaaataaaga gggaatcctt tctgctgatg aaatcaaaga
    41881 aagagaaatt ttaaggaaag aatatttaga aaactttaga gcccacttta gatcaagact
    41941 agatagtgtc aaagtagttt caccagaaga atatgagcaa tacatgaaaa acaataaaaa
    42001 ttagaactta gtaggaggaa aatatgaact taaagtacga atttaagaat gcttgggatt
    42061 ttgaaagaaa agaaaatact attgaacaaa ttatgcaata ttctagcaat tatatggagt
    42121 ttttaagtaa gtcaaagact gaaagacttt cagtaaaaga aattataaaa ttggctaaag
    42181 aaaataacta tatttcaata gatgaagcta tggaaaaagg aagcataagt tgtggtgata
    42241 aaatttatgt tataaataaa gagaaggcag tagcactttt tgtaataggt aaaaattata
    42301 tagaaaaagg tatgaagatt ataggaagcc atatagattc gccaagatta gatttaaaac
    42361 caaatccact gtatcaagag agtaatctag gtttttttaa gactcattat tatggtggaa
    42421 taaaaaaata ccaatggacg gctattccac ttgctttaca tggtatagtt atattaaatg
    42481 atggaacaaa agtggacata tctattgggg aagaagatag tgacccagta ttttgtgtaa
    42541 ctgatttatt gattcatttg gctggagacc aaatgcaaaa gaaactatca gaaggaatta
    42601 gtggagaagc tttaaatata ttaattggga atatgccttt agaagatgaa gaaaaagaac
    42661 ctataacagc aaatatatta aagattttaa atgagaaata caatatagtt gaagaagatt
    42721 tattaagtgc tgaaattgaa gtagttccag ctggtaaggc tagagattta gggcttgata
    42781 ggtctatggt gttgggatat gggcatgatg atagggtatg ttcatatgct gctgtaaaag
    42841 ctatactaga aactgaacaa ccagaattta cttcagttgc attatgtgta gataaagaag
    42901 aaattggttc taaagggaat acaggtatgc actcaaagtt ttttgaaaat actgtggctg
    42961 aactgattgc tttagaagga gattattgtg atattaaagt aagaagagct ttagcaaata
    43021 gtaaggtatt atcagctgat gtttctgctg gatatgaccc aaattttgga gaagcatatg
    43081 aaaagagaaa ttcggcatat atgggaaatg gagtagtttt aactaagtat acaggttcaa
    43141 gaggaaagag tggatgtaat gatgctaatg ctgaatttat gtcagaagta aagagaattt
    43201 ttaataaagg aaatgtagta tggcaaactg ctgaacttgg aaaagtagac caaggaggag
    43261 gcggaactat agcccatata ttggcaaatc aaggtgcaga ggttatagac tgtggtgttg
    43321 gagttttaaa tatgcatgca ccacatgaga ttgtctctaa agtagacata tatgaaatgt
    43381 ataagggata taaggcattt tttaatataa atttataagt aaaaatataa atgtaataag
    43441 tgaataaagg ctgttgtata aacaatttaa tctgttgtac aacagtctta tttttatgta
    43501 aaaatagcaa tttgtcacac tagagaaaat aaaagaaaat actgtcaaat taaaaattat
    43561 tttaaaaaaa attgacaacg atttcatctt gttataatat gtaataaaga acttgttata
    43621 taatgttata aaaatgttac atagggaggt gagcaaaatg gatgaaaaga gacaaaaaaa
    43681 agaaatggat ttagaagtaa attcctttgt tcctttatat caacaactat atgacaacat
    43741 aaaaaaacaa atagcatctg gcatatataa accaggagat aaacttccat ctgaaggaga
    43801 cttatgtaaa gaatttaata taagtcgtat aactgtgaga aatacgactt ttttatataa
    43861 aatagcaaaa taacagtgtt tgagcaaaaa aaagaatgtt ttttatcgtt ttgccacctg
    43921 tttgccacca taactttttt cggtggcaaa ttattgtaaa atgccctcca aaatatctat
    43981 tgtttcactt tccattttac ttgtaacatg tgaatatgtg tccatagtgg ttgataattg
    44041 actatgacct aatctttgtt gtatatattt tacattagct ccattttcta ataataatgt
    44101 ggcatgtgta tgtcgcaagc aatgaaaatt aaagttaata tttagtttct tgttaatagt
    44161 tcttatagca gcgtcaatat tgttgtgatt tacaaatgag ccatcttttt ttctacaaac
    44221 ccaatcatac tcagtttctt tataccattt tccaatttta attttttgtt ttttttgatt
    44281 caatttttcc tcttttaata tcctagacaa agtatcacct attttaatat ctcttattga
    44341 tgtttttgtc ttaggtgatg ctaattcaaa ttctgaaact tttctcttta ttaaattttt
    44401 tctaactttg attatattat tatctaaatc aacattatcc caacaaagac ctaatatttc
    44461 tccttttctc atgcctgtat gaaaccctat aagtagagga atatagatat ttgtattttt
    44521 aggatatatt tctagtattt tattgaactc atctagtgtt atagtcttgt tatctgactc
    44581 attttttacc tttaaaacat tttttggtat actggcatat tgaacaggat tttccttaat
    44641 gagtttgtaa gggtaaacag cagattttaa agcagcattt aatacaacat aaatcgcttt
    44701 taaaactcct tttgtgtagt gtttttcttc tccgttttgt gtgtatgtct cttttgattt
    44761 attatttaaa aattcttgaa taatagctgg atttatagat tttagcttac atttaccaag
    44821 tctaggttct atatgatttt caattaaatt tctataactt tcctgagtat tgtatttgca
    44881 attaagaagt acatactctt tgtaccaaaa gttaagatag tctgataaac tcatatttgt
    44941 ttcatcaaac actataccag cattttcata ttcatttatt gcatcacgga gcgatttttc
    45001 agcttctttc ttagtgtttc caccaactct ttctaccttt tttctcttgc catctactat
    45061 acctgcatca aagtagtaat accacttctt tccacgtttt cttacgccgc ctttcataaa
    45121 atctctcctc tcaaaagctt tttttatgta attatataat aacatatatc aatttaaata
    45181 aaataaataa aaaagactat aagaaacaaa gttttatgtt tataattaat agtctttttt
    45241 atttagatac atatttaatg ttttttatca cgtgattcca gcactttttc tgccaaataa
    45301 acaactattt tttcatactc aatatcagtt tctaaagaaa agtcaacaat agcaggtatc
    45361 gtcatatctc ctgcatattt attacctaac caattttcaa ttaattccaa ttcttctttg
    45421 cttaattcaa attttttctt tttattaaaa cttaagttca atttattcac ctcaaataat
    45481 attatatatt aaaaatagta tttgatagaa acattcgaat tatttatgta attttctttt
    45541 tttaatatat tcatcagcaa aataatttac taaatatttt tcctccaatc ctaaagctat
    45601 ttctaattca ataagagcag ggatagttaa atctttattc tcattatttt ccaacctaga
    45661 aatttgactt ctgtggcaac caactctttt tgctaactct atttgtgtta atttcttctt
    45721 ttttcgtaac tcttttaaca tatatttaac ctacctttta gataatttta tatatgttag
    45781 tttgtgtaat ttcttgtaat aaatgtgcaa tattcgcaca ctttttgttg gaaatttgtg
    45841 ctagaatgta gttaagaaat aactttatct agataaagca aaaataatag aagctataaa
    45901 atataataat attttacagt tattttatag ttttaagctt tgaaaaagag gtggttgtaa
    45961 ctatttttaa gaacgtatgt ttcgtggaat taataaataa aatattttat aggggatgat
    46021 atatttgaat aagacgaaat attatgatat tttaaagtta aacttattaa tgaaaaagtt
    46081 gaaagaattg gataaaaata aaatcaatga atataaaata aaagtgaaag aaatacataa
    46141 aatcaataaa aaagaggaat gattcctctt ttttattata ttcattttca gaaataaact
    46201 attttttatt tttttcgtct agtaaaaata attctgcaac ttttaatgct ttttctcttg
    46261 cgtctgggct tagctcgcta aatatattaa aaacttcttt catatcttcg tcaagataca
    46321 tattctcaat aagctccttt tctgttttaa aattttcagc atcataatct ttttcgtttt
    46381 tatttataaa taagctattt ctaacatcag ttcttcctaa taaataatct gtagacacat
    46441 caaaatagtt tgcatattct tctattgtac ttttcttagg ttctcttaaa ccattttcta
    46501 tccttgatag tgtagatttg tttatatgta aatcctcgct taatttgtct agcgagatgc
    46561 ctttttcttc tctcaattct tttatcctat tcaatttgca caaccccttt ttatattaat
    46621 tccaaaatag caacttttat ttatattata gcaacaaaat taattattac aatttttttt
    46681 gctaaaaaag caacaaaagt attgactata atcacaaaac ttgatattat ataaatatga
    46741 agttgccaaa atagcaaaaa ggaagtgatt taatgtactt aaatagatta gaaggattga
    46801 tgaaggaaaa tagacacacc caaaaaaatg tggcagatat attaggtctt agctcatatg
    46861 gttttagatt aaaattaaaa ggaaaaaacg aatttaaagc aagtgaaata aaaaagatat
    46921 ctaaattata taatgtatct gcggattatt ttttttcaga tgaagttgct aaaatagcaa
    46981 taaaagaaga aaggggcaat aaataatgaa gaatctaacc ataatcaagc aaaataatca
    47041 atttttagtt gaaagtagag aagtagcaga attaatagaa aagaagcacg ataatttatt
    47101 aagagatata agaggataca agaagatttt agaggactca tcaaatttga agagtcaaga
    47161 tttcttcata gaaagtactt atataaatac tcaaaataaa attcaacctt gctacttatt
    47221 aactaaaaaa ggttgtgaca tggtagctaa taaaatgaca ggtgaaaagg gaattatatt
    47281 tacagcgatt tatgtaacta agtttgaaga aatggagcga gagttaaaag aacaacaacc
    47341 taaattacca actacatata aagaagcact gcaacagtta ttaatcgaag ttgaagaaaa
    47401 agagcaatta caattagaaa atcaagtaat gaaaccaaaa gcagattact ttgatgctct
    47461 agtagaaaga aacttgctaa ctaatataag agatacagca aaagaacttg gagtcaaaga
    47521 aaaaacattt gttttatggt taatagagaa gaaatattgt tacagagatt taaaaggcaa
    47581 aataaaacct tactctaaca agatgcagta ttttgaactg aaagaattta caacaccata
    47641 cggacattca gatactcaaa cattaataaa tccaaaagga agagaagcat ttagattatt
    47701 acttataaag gatggactgg taaaagaaaa agaatatcaa ataactttat taggctaaaa
    47761 ttgaaagtac tttgaaaatt aaagattatg gaggtagtta caatgagcga agacatattt
    47821 tatggtataa aaaatactct tgatgaaata gcagaggttc aaattaaaaa taaacaaggt
    47881 gtgttaaaag aagttggaat gttaataagt ggtgaggaca attcttgtat aacgcattgt
    47941 ttagatgaag atttaattaa gttttacata aaagaagagg cagtattgac aatagataaa
    48001 gatagtcatt tgttatgtat gcttgatgct ctattttata actttcttga taaataataa
    48061 atacagaata ttcttgaaat ggtggtgaag aaattgggta atatatctaa ctttaattta
    48121 gataaacaag aagataaaag ttttaatgac ctggataata tatcaatttg tttttcagaa
    48181 ggtattcgta aagttgtaga aatgaattta aacaactata aaaataaaat ctcaaaatac
    48241 ttaaatgaaa cttcgaaaat agaattgttg gaaccaaaag aattaacaat tgttataagt
    48301 aaaggttatc ccgattatct tatgtctgtt gaagaagcaa gtaaaagatt gaaaatagat
    48361 aaagtatttg gatatgagtt aataaaaaat ggacttttga agtcagttga tataggggca
    48421 actaaagttt ctagttatga attagatgat tttataacta ggaatcaagg aaaaaacatc
    48481 aaagaaatgc ttagagaaat gaaagaactt agagaggggg tgatttaatt ggaactagta
    48541 acatacagaa acaagcttgt tttactaaaa gatggagaaa agattgcaac tataagttta
    48601 aaaaggaaat ttctcagcaa cagacttaaa ttaaaaataa gataggagag ataaattgaa
    48661 aataatttat aaaaacaaag tttacaaagt agaacaagac aaaaagttat ttagaattac
    48721 atactatgat gagcagagag gtagtaagaa gtttaataaa gagaagaaag taaaaagaag
    48781 tgttttaaca agagatatag agttagttaa cttgtattta ccagcacatt taaaaataaa
    48841 ataagctata aataattaaa gaaaaaggtg attagatgga aatagaacaa gcaacaatac
    48901 gcctgcctag agaacttaaa gacaagcttc taaaacaggc aaaagttaaa ggatatacat
    48961 taaaagatat gatagttttt attctaaagg attatcttca aaatatttct caagaataaa
    49021 ttcaatttct ctacctatag aacgcttatc tttttgagca agttgttcga ttttctcaaa
    49081 aagaagttta ttaattctta gtgtaaatct tttatcctct tcacgagtat aaatatcttt
    49141 attagacata tttatcattc ctcacataaa atttgacgtc tttatgacac tttaataata
    49201 aaataatata aaagaaaagt caacaaaaat gcttgacgtc aaatatatga catggtatta
    49261 ttaaaacaag aagggagttg acgtcaaata tatgacaaat gaaagagtta gatttacatt
    49321 tagattacca gcaccattgc ttgaaaaaat taaaaataga gcatcaatag aaggtagttc
    49381 aatgaactca cttatattac acatactttg ggattacata aaagaaatag aaaataagga
    49441 ggtcaaataa tggttgaatt ggtaaaagaa tttgatttac aaacaattaa agtaggaaat
    49501 gcagtaaaag taaattgcaa aagatttggt tttgaaattg attgtatagt agtagtagca
    49561 acagaaaaag aattaaattt agcatacttt gatgaaggta gaggctgtat ggagtatcaa
    49621 gccttaataa cagaagatat tcaagatggt gattatgaga ttaaaatttt atcttaggag
    49681 gaaataaaat ggcagcttta ataatggtag gtttatttgc aatatgttta gtaggattag
    49741 tacaaaatag agattaagtg aaggggtgta tttagatgga agcagctaga ttaatagcaa
    49801 tgggtcaaat taaacaggct gaaaaagaaa taagtaaatt gcaaggtaca aaaaacaata
    49861 gtagtttaat gtggtgggaa gccgtaaaat ttgctagtca aaatatatta caagggttgg
    49921 aacatgatat agagctagaa gcatcaactg atttcaggga gtttatgata acacaagaag
    49981 aacttgaaag agatagacct atagatgtgc agatataaga aaagagccta gggtgaggct
    50041 caattcaaat aaatattaaa aaatttaatt aagctaatta tagcataaac ggagggaaat
    50101 tatgagtact ttatatgaat taactacaga tttattagaa atagaagaag gtttaacaga
    50161 aataacagga aatgaagctg aaaaactaga ggaaataaaa gaaataataa aacaagagat
    50221 acaaaataaa aacactagga tagtttcagt aatattaaac attgacagtg atataaactc
    50281 tatagattca gagattaaaa gactgcaaga gttaaaaagg gtcaaaaaga atactcttga
    50341 tagattaaaa agcaatataa aagactgtat ggaattactt ggtactaaaa aagtagaaac
    50401 agttttagga aatataagta taagaaagtc agcaggtagc ttagtcatag aagatgaaga
    50461 aaagatacct gctatatata aaacagtaga gcaagttgta aaagtagata agaatatcat
    50521 taaagacttt attaaaaaag gtcatgaggt tgaaggttgc aggattgaat atggaactac
    50581 actaacaatt ccaaaagcta aaaaagagta ggtgaggacc atggaaacta ataatgttta
    50641 tataaaactt gtaaatatac agagtacttt aaaagctcct aaaagtcaat ttaatagctt
    50701 tggtaaatac aactatagga gttgtgagga tatactagaa ggtttaaaac ctattctaaa
    50761 ggaagaaaaa gcattagtta tattggatga taatattgtt cagataggaa atagatttta
    50821 tgtagaagct acagcaactt taatagatgc agaaacagga gagaaagtat ctacaaaggc
    50881 attagctaga gaagatgaaa ctaaaaaagg tatggattta gcacaagtaa ctggaagtgt
    50941 atcaagttat gcaagaaagt acgctttaaa tggattattt tgtattgatg atacaaaaga
    51001 tagtgatgca acaaataaac atggaaatga gcagaaaaaa aaagaagtta atgagagtga
    51061 attaaataca ctatattcgc taggagaatc tatagaaaaa gataaaaata gagttgatag
    51121 tgaagtatat aagaagtttg gaaagttagc agtagatttg actaagcaag agtatgagaa
    51181 agttttaaat ggatataaga gcattttaga gaagcaaaaa caagagtagg tgatagtatt
    51241 ggggattata agagtaagca aagacaaaga taatccatat gtagttttaa ataaaacttg
    51301 tttggaagat gtaaaattaa gctggcaagc aaaaggttta cattcatatc tgattagtaa
    51361 gcccgaccac tggaaaatct atgttaatga cctttgcaag agaagtaaaa atggaagaga
    51421 tgctacagca aatattttaa aagaacttat agaaaatgga tatataacaa gaaaaccttg
    51481 tagagattct aatactaata aaatgcttgg agggtatgat tatgaagtat atgagatacc
    51541 acttgaaaat cctcagaagc taaaatcccg aaaaactgat ttcccggaaa ccggatttcc
    51601 cggaaaccgg gtttctcgga aaccggaaaa cacggaagta gtaagtaatg actttaaagt
    51661 aaataatgat attactacta ttgttattaa tgaacaatcc aataaagaca aaaccaccta
    51721 tataaaaaaa tactttgaaa aatatatagg tgtgattact cctaataact ttatagagtt
    51781 aatgagttac ttagatgatg gaatggaagc tgatgtaatt ataagagcta ttgatgaagc
    51841 aatatcaaat ggagttaaga attataagta tgtaaagaca atattaaaca attggataga
    51901 agcaggtgta aaaactaatt tagaacttac agagtatcaa aatgagtttg agaggaagaa
    51961 aaagagtaaa caggagaaga aacagtctaa taataaagct gtgaatactc ataatgtgaa
    52021 taaaaataaa tttgctaact tcaatcagac tttcactcaa tatgaagaaa aagagctaga
    52081 tgagattatt aaaaagagtc agaaggaaaa atttaaataa aattaaactt ctaggaagta
    52141 aatatcaata tattgtttcc tggaaaaggg aggtataaaa tggcgagaat atatgcacaa
    52201 agaagtggtt ctttaaatga gcaggataga ttggaattgt taagattact tgggaaagct
    52261 ggatatacag taaagattgc tagagagaag caaaatagca agacaactta tacttacttt
    52321 gttgagtata cagaagagca ggaagaaaaa tagaaggggg ctagttaaat gaatacaata
    52381 actttagttg gaagattagt tgcagatgca gaattgaagt accttccaaa ttcaggtact
    52441 ccaaaaataa ccttttcaat ggcagtagat agaaggttta aagataaaaa tggaaataaa
    52501 ataactgatt ttattcaatg tgagcaatta ggaaaacatg tagagaattt agtgcaatat
    52561 cttgttaaag gtaagcctat atatgctgtt ggagagttaa atatatataa ttacaaagat
    52621 gaaaatggtt gctggaaatc tattactaag gttaatgtaa atgctttaga actactttct
    52681 agtaaaaatg ataataatgc taaacaagaa tatgtaccac caggattaga cccacaaggt
    52741 tttcaagcaa tagatgatga cgatatacct ttttaattaa gttaaatagt ctagggagta
    52801 attatacaat attacttcct aaaagttaaa aatggaggga taaagatgag tagaacagct
    52861 atatgtagtg tttgtgggga gtttttagtt gacagttatg gtgataaatt tacaaatgct
    52921 aaagttatag atttgtatgg tagagaattt gtaattgtta tatgtaagag ttgcttagaa
    52981 gaattattaa gaaaatgtga ggactaacaa tatgagattt gagataggta aaacttataa
    53041 gtttgataaa gagaaattta tggaaattaa tggtgtagaa caacataaaa aatataaaga
    53101 actttggatt gatgatattg aaggtgttga atttactgtt gaaaaaactt ttgatgatgg
    53161 ctatgtttgc tatccaaatg aattttggtt taattttggt gtagtttcgg aatggtgtgt
    53221 tgaagttaaa taaggtagga ggaattagat atggctaaaa tttggtt
//
LOCUS       DAFAZV010000027        49456 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFAZV010000027 DAFAZV010000000
VERSION     DAFAZV010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 49456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49456
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.027"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            107..649
                     /locus_tag="KOU88_002269"
     CDS             107..649
                     /locus_tag="KOU88_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3212143.1"
                     /translation="MKICITVGHSILKGGKSTGVNGIVDEYNYNKKLAPMLAEMLISQ
                     GNTVDVIICPERHFMSEREEFFYRVPKVNSGKYDLLVELHLNKADGTQCGTEVLYYGT
                     EGLEYAKRVSNRLGELFENRGAKKRENLYILRNTNPVAIQIESFFCDNVNDCNKANES
                     GYDYIARLITEGILNKDINM"
     gene            977..2470
                     /locus_tag="KOU88_002270"
     CDS             977..2470
                     /locus_tag="KOU88_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK3212144.1"
                     /translation="MKYTFEKFKLNEKILKSLKSLGYNIPSRVQREVIPKLLKGQNLV
                     VRSKTGSGKTASFAIPLCENINVDYNNIQALIVVPTRELALQVKDEISDIGRLKKVRC
                     SAIFGKQSIKDQIAELKQRVHIVVATPGRILDHINRGSIKLENVKYLVIDEADKMFNK
                     GFVEQMEKILLNLPKEKIVSLFSATIDEEIKYICEKYMLDYSVINIEENESDTNQKTR
                     QIDDKIIKANGREKYILLKELIYSENPKSVIIFCNTKEKVSKLYNKMSKEGFLIRELH
                     ADLSQERRIFVIKDFKNQKFNILVSSDVASRGIHIDDISLVINYDVPQDKENYIHRIG
                     RTGRKGNSGKAITIVTEKDEKYIENIETYIGYKINELKDIEKSRITHGKVLFEEYSKG
                     ILKKVSKRKKVDKNSYKSKDIKLNIESEVVKLYLNAGKKKKIRVLDIVGAFSNIKGIT
                     NDDIGVIEVQDLCSYVDILNYKGDLILKKYKEIPIKKKMVKVKRDIR"
     gene            2544..2777
                     /locus_tag="KOU88_002271"
     CDS             2544..2777
                     /locus_tag="KOU88_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212145.1"
                     /translation="MKAEDMKRKVSPIDLERILVTGGVIKHEDSIWLLDFWGNKDIAG
                     ILLMPPTRHVILHLNDCCKWKEYFRTKKKFYRS"
     gene            2933..3697
                     /locus_tag="KOU88_002272"
     CDS             2933..3697
                     /locus_tag="KOU88_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3212146.1"
                     /translation="MAYFNYNDKQCYYNEIGDGTPLLFLHGNTASSKMFNDIINFYKD
                     EYKVILIDFVGHGKSQMVDKFSADLWFDEAMQVICFLEAMNYKKVNIIGSSGGALVAL
                     NVALERPDLVNKVIADSFEGEVPLESFVQNVKIEREASKQDDGAKAFYIYNQGENWEK
                     VVDNDTEAIFEHYKTIGKFFHKPLETMQPEVLLTGSREDEFVSLISSDFFENTFSLLL
                     EKIKNGKMYLFDKGGHPAILSNGLDFSNVAKKFLEE"
     gene            complement(3982..7161)
                     /locus_tag="KOU88_002273"
     CDS             complement(3982..7161)
                     /locus_tag="KOU88_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK3212147.1"
                     /translation="MKIDMIYKLIRRNTEPSRWSRGVKYYTNQLVDYIDIDIDDLQNN
                     LLTFRGGVNSEDNYSFYFNSITIDIKHFKIIENDCSCADCQSKGKSIFICKHIVAIVI
                     KSLKQIKNKKDVPPILIDILGADKDKLSNTNSKTSLDLSKQLLSLLDNTKRERVNLDV
                     LINVDSNKAIAEFKIGINKMYILKNITEFAYSKLNGYELDFGKKFTYNPNTHYFADED
                     EKLVDIIEEYGTNLSYNFSSSHSKKFMEINASSLKQFLNAIKYKDFTLIFSKEEYHPK
                     ILNDTLPVRFDFKNIEDKIVLYSKDSLPVPLTKKNDVLLYDGNIYLLSHKKAHDYSKI
                     YQILSKTKELKFDKEDSKDVLGLLVPRLKSISQEVHLDDNIKNNITKDFKSEFYFDMI
                     DGNICCDVKYIYDDEDKKFVLPNIQKEATIENKLTSSQFTKENNHYVFKGTDHDLFTF
                     LDLQLESLKEFGDIYYSEKFKLKKIYNASSIQASINQTNQNYLEFNFNISDINPKEYK
                     DILKAFQEKRTFYKLKDGNFIDLSERETKDFFELVENLDIMDKSKNNKIHKNKALYIN
                     DVIRSKNLKFIDGKKELDSICEKFRNFDSINLEIPANLNANLRDYQINGLNWFKVLDY
                     YKFGGILADEMGLGKTIQTIAFLLSLSNKKSLIVTPTSLIYNWKNEFEKFAPDIKVLL
                     IHGNKRDREKCFMELENFDVILTTYGTLRNDLEKYSEIKFDYCILDEAQNIKNPVALV
                     TESVKSINAENKFALTGTPMENNLLELWSIFDFIMPGYLYSKAKFQELFINKEDNVKN
                     LKKLIKPFILRRSKKQVMKELPDKIEKNFFVELNKEQKKIYSVYSKDIQDKMKDKNLK
                     KDKIVIFSYLTKLRQLCLDPSIVVKDYNKKSSKIETCLEILRDSINENHKILLFSQFT
                     SVLKNISKELDKYKIKYHYIDGKTNAKERLELVDEFNNSMDKKVFLISLKAGGTGLNL
                     TSADMVIHFDPWWNPSVENQASDRAHRFGQKNSVQVIKLIAKGTIEEKIIKLQESKKE
                     LINQFINGELSNEGVLKSLSDEEIINLFN"
     gene            7442..9619
                     /locus_tag="KOU88_002274"
     CDS             7442..9619
                     /locus_tag="KOU88_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="HBK3212148.1"
                     /translation="MYNKYNNLYLLLGKENVNMDSYKQLKAKIPCKETGIEIKRTLCD
                     ICSPGVHCGIDAYVKDGKVIKIEGTKEHPMNKGLLCTKGLCNREYIYREDRIKTPLKR
                     IGKRGEGKFKPISWDEAYREIAEKLNRVKSEYGAKHVAFFTGYGKWYRPFLQRFASSF
                     GSPNYGTESSSCSTSAQMAGNVATGRNFTMQDMENAKTYLGWGFNPYYSKFLNSVNLI
                     KLKEKGLKFIIVDPRITPTTQKLADLHLRIKPGTDGALALGMANLFIQKDLIDREYIE
                     KHVHGFNEYKEYVKLFDLDTVSRITGVSKDNIVKAVEMLSQGPFCINESAAPIVHHQN
                     GFQNYRAMMSLSAITGNYDRIGGNIPKQDYFAGKIGGFQTLEKEFVKEVLPKNINERI
                     GGERFPLWNEMVTQFQAMDLPRQIEEKTPYEIRALFCHGINARMFPNSGRLFKALNSV
                     DFFVNIDLFMTDTSKYADILLPACTSFEREECKSYPGGYITYTKKVIDKLYDSKSDVE
                     ILSDLANAMNIDDDLLKAGYEASVRHMFKNTCVDVDKLKESDLPLKCKDFKPYIVGSY
                     TREGYDTSTSRFELKSTIIEKYKDFGLDALPTYRGFNDNIDDEYTHLLTSGARISNAL
                     HSRLHDIKLSRILKNEASCDISSLDAKELGVISGDYIKITTKIGSLDVKVNVTDRVLY
                     KNIHMYHGYREADINSIICDNFDPYSGFPAYRSCKCKIEKMNR"
     gene            9633..10055
                     /locus_tag="KOU88_002275"
     CDS             9633..10055
                     /locus_tag="KOU88_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3212149.1"
                     /translation="MKSLFKFNKELCTACGACLLACIDQNDNNIDNGELFRHVFTIEE
                     GENIEYFSLACIHCNEPKCLGVCPKNCFKKEEGFVVLDNQNCIGCKLCEKACEYGALI
                     YGNDGKANKCNGCIERYKCGMDSPCVMVCPTGALKFNK"
     gene            10463..11266
                     /locus_tag="KOU88_002276"
     CDS             10463..11266
                     /locus_tag="KOU88_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBK3212150.1"
                     /translation="MKKLKLIIMFALVSALLVTGCSSGNNKNKEEQKVIRVATSGTYY
                     PFAFKDKDKLKGFEVDFWDEFAKRTNCKVEWVLTDFSGLFGLLEADKADVVSAQLTAT
                     PEREKKYAFSDAYNYSGTNIIVREDDTSIKSIDDLVGKKVGVGTGAVANEILKEKYPN
                     DEIKIVNYSSATLKGNYQDLEMGRLDAVVAQDVEALIAIKEQKLNLKMIEPPIQFGAC
                     SFALQKNEKGEKWTKEINEVIEEMYKDGTLTKISENWLGKDITKEPINE"
     gene            11259..11927
                     /locus_tag="KOU88_002277"
     CDS             11259..11927
                     /locus_tag="KOU88_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK3212151.1"
                     /translation="MSNFNFEFCLSIFPFLIKALGITILISIVAFFLSILLGVILAFF
                     TQTKSKVLQYITRVYVSFFRGTPLLIQIFFFYFGFPMIFSFMKDCSPYLAIVICLGVN
                     SSAYMAEIIRASIESVDKGQQEACYAFGLSKYQSMVKIILPQAATSAVPPIVSCTLDI
                     IKGSSLGLTIGIQDLMGVAQVEAASSFKYFEIYMITILIYWAVSIILSNIQSKVEKRI
                     RRAY"
     gene            12163..12825
                     /locus_tag="KOU88_002278"
     CDS             12163..12825
                     /locus_tag="KOU88_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK3212152.1"
                     /translation="MAFNMKYFLELFPTIMKSFNVTVILAISSLVFSLIIGTIVALSS
                     YYKVKVLNQICKVYVSIFRGTPLMPQLFFLYFGLAYMSDFVKNMDPVFATSIVLSLNM
                     GAYMSETIRASILSIDTGQIEAAYAIGLTNLQTMKRIVIPQAVRVALPSLFNNFIDLI
                     KGSSVAFVVGVNDIMGAAKSQGALSFKFFEVYGAVMVIYWCIITPLGWGQKKLEKKIS
                     NY"
     gene            12885..13682
                     /locus_tag="KOU88_002279"
     CDS             12885..13682
                     /locus_tag="KOU88_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3212153.1"
                     /translation="MIKRNIIKCLVAVLSLTFVITGCSKKEEVKNEKVITVASSNSAD
                     PYSYVDNGEHKGFEVDMWKEIGKRSGYKIKMEPTGFSSIFGMLDSGKVDVAANFFGMS
                     KERLEKYDASIPYGSDSVCIAVKDGNNEINKLEDLKGKVVAVSEGSQGQQVATSVNKD
                     NLFQEKVYGDGTSGLQDLDLGRVSAWIDAELTIVGDAKKANMKVRVLDKKLSATNIAY
                     FFKKNDDKSKTIKEDVNKAIEEMLADGTVKKISEKWFGMDVSADIQK"
     gene            13800..14990
                     /locus_tag="KOU88_002280"
     CDS             13800..14990
                     /locus_tag="KOU88_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3212154.1"
                     /translation="MEVLQMIETKIKSIALKNREKIIKIRRQIHSNPELAFKEYKTSK
                     LIKEELNKLNIEYINIAGTGVLATIKGKNNGGKTILLRADMDALPIKEENDLEFKSIN
                     DNMHACGHDAHVSWLLGTAMILNDIKEELNGNVKLLFQPGEEKGGSDIVIKENVLEGV
                     DALATGHCWPTIESGKIGIARNCAMAATNTFEITIIGKGGHGAEPHNCIDPIAVGNAV
                     YSSIQQIVSRKIDPVVPVVVSVCSFNSGVSKNIIPDVCTLQGTIRAISKEQVIEVSKI
                     LEYIVKNVCKAHGADCKFEKSTGGDAVINDKNMIEIGRESACKILGAENVEIIDFPAM
                     TGEDFAIYMKEKPGLFMYIGVGDKEKNINYRLHSNKFNIDEKCLSIAPSLFSQLTVDY
                     LCQL"
     gene            15099..15848
                     /locus_tag="KOU88_002281"
     CDS             15099..15848
                     /locus_tag="KOU88_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK3212155.1"
                     /translation="MIKVENLHKSFKGTEVLKGINLEISQSEVVAILGSSGTGKSTLL
                     RCLNYLVEPTKGKIMIGDVKVDVEKATKKDITNLRKHTSMVFQNYNLFKNKTALENVM
                     EALIVVHKKSKKEAREISLKLIDKVGMLDRKDFYPSKLSGGQQQRIGIARAMAVNPNV
                     ILFDEPTSALDPELVGEVLSVIKSLAKEGITMLIVTHEINFAKEVADKIIFMDNGVIA
                     EEGTPDEIFNNPKNERTAKFLNIIRKEEVFS"
     gene            16439..17500
                     /locus_tag="KOU88_002282"
     CDS             16439..17500
                     /locus_tag="KOU88_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBK3212156.1"
                     /translation="MRDFLKNYKSSIILLACTIVGAIVGLVLGPKASILKPFGDLFIN
                     ALLMIVVPLVFLSVSSGVASIKNMERFGKIMKGTAIVFMGTTLVIAFLGITSALLFNP
                     SKGLDVSSVKNLMVAQDAETLESKGTLLDQVVSSITVKNFGDLFSSSNLLQLVIFAVL
                     IGTAIAMMGDRGNTIRKLLSEGTEAILKVVSIFMLYAPIGLGCYTATIIGELGSKIIQ
                     GYVRVFVIYSLTAAMYFLLFYSLYAFLSAGKQGFRQFWRNAIKPIATALATSSSSACI
                     PSNLEASKNIGVPDDISETVIPLGINIHKDGSVLAVIIKVAFLSGILGSGMANPATIG
                     QLFITVFVVGVFMAPVAGG"
     gene            17513..17710
                     /locus_tag="KOU88_002283"
     CDS             17513..17710
                     /locus_tag="KOU88_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HBK3212157.1"
                     /translation="MLVVSIFGFPVEAIPLLTVITTITDIPNTILNTTGNTVSSMLVS
                     RLVEGKDWLIDKTAITTKKIS"
     gene            complement(17874..18578)
                     /locus_tag="KOU88_002284"
     CDS             complement(17874..18578)
                     /locus_tag="KOU88_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK3212158.1"
                     /translation="MQQGSDYLKKFLEKHIDLLKKIPLFEGIKSDELEEMLECLGVVD
                     KTYPKDSIIFSVGSEVTSIGIMLKGSAHIIKEDIEGNRNIVAELLPGDLFGEVFACTR
                     LHKSNVTVTTTSSCEVLFIKFKSVTGICSSACVFHNRLVENMLQLIAEKNILLHNKIE
                     LLSRKTTREKLLMYFSKQIEQTGSHQFTIPFSRNEMADFLCVDRSSMSRELGKMRDEG
                     LLSFNKNKFEIFYFKK"
     gene            18743..19468
                     /locus_tag="KOU88_002285"
     CDS             18743..19468
                     /locus_tag="KOU88_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3212159.1"
                     /translation="MMRKIIKIDEEKCNGCGLCVEACHEEAIGMVNGKAKLLRDDYCD
                     GLGDCLPTCPTNAISFEYREAAEYDEAAVKANMEAKKAQKKTLACGCPGSQSKSINRE
                     VSNSTSISNDIVEIKGSQLNQWPVQIKLVPTNASYLKNASLLIAADCTAYAYGNFHNK
                     FMKNKVTLIGCPKLDEVDYAEKLTEILKENDIKNIVVTRMEVPCCGGIVNAVKTALQN
                     SGKMIPWQIVTISVDGKIVDGEI"
     gene            19528..21120
                     /gene="hcp"
                     /locus_tag="KOU88_002286"
                     /gene_synonym="priS"
     CDS             19528..21120
                     /gene="hcp"
                     /locus_tag="KOU88_002286"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBK3212160.1"
                     /translation="MEKMFCFQCEQTAGGKGCTINGVCGKKGGTANLQDELTGVLIGL
                     SRATIGNKNRPTSETDKIMIEGLFTTITNVSFDDEAIKRQIEKTEVEKSKLVPRCSDC
                     STTCNRNDNYDMKDLWNDNEDIRSLKSLILFGLRGMAAYAYHAMVLGYTDKDVNEFFY
                     EGLIAVGGDLSIDELLGLVMKTGEINLKCMELLDRANTETYGTPEPTQVSMKIEKGPF
                     IVVTGHDLYDLHKLLEQTKDKGINIYTHGELLPAHAYPKLKEYKHLKGNFGTAWQNQQ
                     KEFDNIPAPILFTTNCLMPVKDSYRDRVFTTEVVAYPGMVHIDEDKDFSSVIEKALEL
                     GGYREDVHMTGINGGDTLTTGFARGTVSSVQDKVVDAVKSGAIRHFLLVGGCDGAKPG
                     RNYYTEFVKQAPKDTVILTLACGKYRFNDLDLGDIGGLPRLMDMGQCNDAYSAIKVAV
                     SLANAFECGVNDLPLSMVLSWYEQKAVCILLTLLHLGIKNIYIGPSLPAFLSKNVLDI
                     LVDKFALTPISTPEEDMKKILG"
     gene            21492..22397
                     /locus_tag="KOU88_002287"
     CDS             21492..22397
                     /locus_tag="KOU88_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBK3212161.1"
                     /translation="MKNSNFNILAFDGGGLKGALSISILERIVKEYPNLLNNINMFGG
                     TSTGSLIALGLAYGVSPKEIKELYSIENSKYIFNKSYAEILRPKYENKNLKEVLLSIF
                     PEELELKDLNKLVMIPSFYIGNEENAWKPVFYNNMPNSFTKTSKVVDVAMASSAAPVF
                     FPTYNRHVDGGIIATDPSLACIIHAIDSGFKLKNTRLFSIGTGYVYNSIKADTTEWGA
                     IDWIINKEPDLPIISITLEGNSQMSQLFSQKLLGDNYYRLNPKMEKNVAMDDCDALEY
                     LMSLGENCDIKDAFGWIKKKSFYRN"
     gene            22521..23474
                     /gene="msrA"
                     /locus_tag="KOU88_002288"
     CDS             22521..23474
                     /gene="msrA"
                     /locus_tag="KOU88_002288"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK3212162.1"
                     /translation="MIKLATFAGGCFWCMVKPFDKYDGVIKVVSGYTGGHVENPTYQE
                     VCSGTTGHLEAIQITYDDDIISYDELLNIFWKQINPTDDGGQFGDRGTQYKTAIFYHD
                     EEQKNIALESREHLENSKIFDSKIVTDIIPATKFYEAEENHQDYYKKRPLNYNMYYKG
                     SGRYNFVKSHWDGNNINREELKKTLTPIQFEVTQNDMTEVPFENEYYDNNKEGIYVDI
                     VSGEVLFSSKDKFDSGCGWPSFSKPVIDKSIIERSDFSQGMYRVEVRSAKGNFHLGHV
                     FDDGPKELGGLRYCINSASLKFIPRENMEALGYGEYLKLFE"
     gene            23627..24757
                     /locus_tag="KOU88_002289"
     CDS             23627..24757
                     /locus_tag="KOU88_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212163.1"
                     /translation="MNLKDFNGKRLKSARIFRAKTIEQLSKETKINKKDLKAFEENKY
                     VPNIENTLKLSNILNFPKEYFYKNENINIVVEDSHFNPQSKLPRVEEISYREKIIIIH
                     KIYSFMENYIKFPKENLPNRKVMSDININDIESLAYKTREFWDLNSTPIVNMVSLLES
                     KGIIISGMNVDRKGATIFTQKQRISKESKYLISLGNDKKSASIRNYTLACELGYIISS
                     ELRIPSKQFSEDEYACAFLLPKESFLKDLTHPEDLDYYVELKKKWIVPISAMIFRAYN
                     LEKINYKKYNYLMNEMDKKGWLIEEPLDKMKGSSPTYLKRAVELLIENKIMSVNSIVS
                     SLEEFGINLYPEDLELLMGLKKGLLSQEVNKKSKVIKFDGKK"
     gene            complement(24874..25842)
                     /locus_tag="KOU88_002290"
     CDS             complement(24874..25842)
                     /locus_tag="KOU88_002290"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBK3212164.1"
                     /translation="MAIKPRKISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSK
                     AQALDLADAVSYLPHKVHIEKGTFSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRP
                     TIGMIKSIVKPIVDSGFDGIFVVISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRL
                     RRILSEETGIAQQSIQAYSMGEHGDSQMVPWSHVSIGGKPILDMIKDNPSTYSNLDLP
                     SIVEKNKKTGISIINGKDCTEFGIGTALVEIVKAILHNEKKVLPVSTLLEGQYNERNV
                     FAGVPCVIGKDGIEEIIEINMTEYEQNEFNKSCSVLREYIALSKTL"
     gene            26177..26365
                     /locus_tag="KOU88_002291"
     CDS             26177..26365
                     /locus_tag="KOU88_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212165.1"
                     /translation="MNYHTKEELVEALRVVSSSIINCGKGQKKFSEETSHHTCFKNII
                     EVMYISKSLIMDEISKRD"
     gene            26625..27824
                     /locus_tag="KOU88_002292"
     CDS             26625..27824
                     /locus_tag="KOU88_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA editing protein AlaX-L"
                     /protein_id="HBK3212166.1"
                     /translation="MEKLYYTNQYIRDFTAEIIEIKEVENKYHVLLDKTAFFPGGGGQ
                     FGDLGKIENDDVINVYEDGKKIYHVLDKKPIKIHKVKCSIDWDRREDGMHQHFGQHVL
                     SGCFFKTFNANTTGFHLGNEYSTVDIEGNLEEDKIREIELFANEIIRQNIQVETLLPT
                     KKELKKIWLRRDLPNTDEEIRVIKIGDLDTNACCGVHPKSTGELRMIKIKKWEKHKSS
                     TRIEFLAGKRAVDEVLKRDIYLTKICRYLSCSEEDAINGIVNLNSKVEEALIKKRRLE
                     EVVSTYQVKEMIEKANKVGNISVIKKIYDDEDLKYVNKIANKIAEYENSIALLAVKFN
                     DKINLVFACSKNLKDINMGVLLKDAINLIDGKGGGSKVLAQGGGKNNGNLEATLDYAF
                     MKIEKTL"
     gene            27876..28379
                     /locus_tag="KOU88_002293"
     CDS             27876..28379
                     /locus_tag="KOU88_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3212167.1"
                     /translation="MEQQKDYIELYENEELIEIREARMDDLDTIAKFNYNLAKETEGK
                     ELDMDVLTKGVKALLLDERKGKYHVYTVFDKVVAQIMYTYEWSDWRNGNFLWIQSVYV
                     DKEYRRKGIFNYLFNYIKNICDKDENIVGMRLYVEKENINAKATYESLNMYECDYNMY
                     EYEVIHS"
     gene            28486..28803
                     /locus_tag="KOU88_002294"
     CDS             28486..28803
                     /locus_tag="KOU88_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212168.1"
                     /translation="MGVLKGMFYVFLFLDLVSIFCFFFNKGKIASNKIVFNAIGVLTF
                     VLCFMLFSYYPNNNLIGKFIASLFFIFGVAGVMLKEKNFLYARLLLTVVIVFSTLRLF
                     VIQ"
     gene            28961..29920
                     /locus_tag="KOU88_002295"
     CDS             28961..29920
                     /locus_tag="KOU88_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBK3212169.1"
                     /translation="MIESKKSEKLLLSIIYIIFLVYILMIIRIILFRDVPIYAIFKGT
                     FRNVNLIPFYTIYQFIVDSNLDFMKATVNIIENIGIFIPMGIFLPIVCKNLNKKTIII
                     VIILVSLAFELTQYIFALGSSDIDDVILNSLGGIIGINIYINMNKLFPNDINRFKAII
                     GTSLVLGVIGLGVISKNYHNLLTFKFRPDRKISKILIEENREIIKDINKDTVDIVGTF
                     ESFKKGIITIKAGSNNKVKRPENLIDSDGNIRIYLNENTKLVSYIITKESKMDIVKYE
                     EFDVKNLDLLRRYDTINVWIDKENQPKDKHGIMASKLLIGLYE"
     gene            30035..30820
                     /locus_tag="KOU88_002296"
     CDS             30035..30820
                     /locus_tag="KOU88_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212170.1"
                     /translation="MEIIKYILYFFIYSFLGWTVESIGCSIASKRIINRGFLNGPICP
                     VYGFGAVIVISLLGRFNNVVIVFLLGMILTTILEYFTGFILETLFHAKWWDYSDRKFN
                     IKGRVCLKNAIYFGVMSVLIIRFIHPFIKYFVSIIPYRILISMAIITTLWTILDLIVT
                     IITLKKLDIKLNLLDDIITDLNDINVKLDKFDRGEIQALFKTINNDELEVREKINKIN
                     SKLDRIESNIILQKRVIKAFPHIKHKKQQEQLEHFKKIINEKR"
     gene            31112..32431
                     /locus_tag="KOU88_002297"
     CDS             31112..32431
                     /locus_tag="KOU88_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class III-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBK3212171.1"
                     /translation="MSEITSQMISTEEKKYVAKTQKIPYYPVAFKSGDGAMLYDYEGN
                     EYVDFLASAGSANVGHGNKEISQAVKEQMDDITQYTLAYFHSDPPVKLAEKLVEIAPG
                     DNDKKVLYSATGSACIDAAIKLARGYTGRTKIISMCESYHGSTYGAISISALSTNMRR
                     KMGPLLPEVYHFHYPDKNRTAKECLDEIEYAFAHYLPAEEVAAIFIEPIAGDAGIIVP
                     PVEWVQGLSKICKENGILLVSDEIQQGMGRTGKWFGIENFGVEADLIVLGKSVGGGLP
                     LGAVVGRTEIMQSLDAPAHLFTLAGNTTVCVAALKSIEIIEKENLLQKSIEMGDYIKA
                     GFEKLKEKYDIIGEIRGIGLSIGVDIVKGKGSNEKHPDATAKICYRCIQTGLIMIFLG
                     QSTLRVQPPLVITKEQVDKAMNIIDSAIDDYLNGRIGDEVYEVTQGW"
     gene            complement(32506..32934)
                     /locus_tag="KOU88_002298"
     CDS             complement(32506..32934)
                     /locus_tag="KOU88_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212172.1"
                     /translation="MKDNNNTNKTIQFGEKKASLENNIQKNKNIKLDNTHKVIPYPKN
                     RKKDDKKKGNKKKNTNTSKVNKNNYGHSFFNNKYKYKRKPYVIALYTVILILLAILII
                     TKLTDSTNKGNYSRNTVSDTHKNDIRNIVFNESNNFLICG"
     gene            complement(33025..34401)
                     /gene="hydG"
                     /locus_tag="KOU88_002299"
     CDS             complement(33025..34401)
                     /gene="hydG"
                     /locus_tag="KOU88_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydG"
                     /protein_id="HBK3212173.1"
                     /translation="MFINHELINSLLEDAKNSTSDDIEKVLDKADRREKLSYKDIATL
                     LEVEDKKQLDRLFSIAGQIKNEIYGNRVVLFAPLYVSNYCVNECVYCGFSKCNKFKRK
                     KLTMEEIKEEVKILEKMGHKRLALEAGEDPKNCDINYILDCLDAIYSTYNENGNIRRV
                     NVNIAATSVDEYKLLKEKGIGTYILFQETYHKPTFIKMHGQSIKNDYYYHLTAFDRAM
                     EAGVDDVGAGVLFGLSDPKFEVLGLMMHNEHLEEKFGVGFHTISFPRLKKAEGMSLED
                     FPHLVSDDMFKKIVAITRLAVPFTGIIMSTRETAEMRNELLKYGVSQISAGSLTGVGG
                     YKAYEDGDNTEQFEVGDHRSPVEVLKELITDGYIPSYCTACYRKGRTGDRFMSLAKSR
                     QIHNVCTPNALTTLNEFLIDYGDEELKIMGKKLIAEEIGKIEREDIRNIVSNNMTALE
                     RGERDLYL"
     gene            complement(34402..35487)
                     /gene="hydE"
                     /locus_tag="KOU88_002300"
     CDS             complement(34402..35487)
                     /gene="hydE"
                     /locus_tag="KOU88_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster radical SAM
                     maturase HydE"
                     /protein_id="HBK3212174.1"
                     /translation="MTKNKIKYFIDKLYSINSLSFDELLYLIENIDNEEYNFEQNLRN
                     YLYKQASDMRNKHYGNRVYLRGLIELTNYCKNNCYYCGIQSSNKNIIRYRLSLDEILE
                     CCDIGYKIGYRTFVLQGGEDAYFTDDKICEIVSSIKNKYEDCAITLSLGEKSYDSYKK
                     YFLCGADRYLLRHETATDSHYKKLHPPNIELRTRKECLKNLKEIGYQVGAGFMVESPF
                     QNNEDLVRDLLYLKELNPHMVGIGPFIPHHDTIFKDYKHGDLEKTLLMLSITRLLLPK
                     VLLPATTALASINPSGRNAGLLAGCNVIMPNLSPQEFRKQYSLYDNKAFTGQEACEYH
                     QSLEENIKSLGLEVDYSRGDNIEWRRL"
     gene            complement(35523..36731)
                     /gene="hydF"
                     /locus_tag="KOU88_002301"
     CDS             complement(35523..36731)
                     /gene="hydF"
                     /locus_tag="KOU88_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[FeFe] hydrogenase H-cluster maturation GTPase
                     HydF"
                     /protein_id="HBK3212175.1"
                     /translation="MSLNSTPQSVRVHIGLFGKRNAGKSSIINAITNQSAAIVSDIAG
                     TTTDPVFRPMEILPIGPCVLIDTAGLDDVGELGELRIGKSLDVLEKTDIALLVVDCQI
                     GISQEDLSLIEKFNDKNIPHILILNKIDTIKNQSEILNLTKNKVKCPVVSVSSTDKIG
                     IENLKNEIIKVLPKDSTEFKLVSDLIEPNDLVVLVVPIDKAAPKGRLILPQQQVIRDI
                     LDNGAISIVTKEDSLKETLSNLGKKPKLVITDSQVFPQVDKDTPKDIPLTSFSILFAR
                     QKGDLKELINGAYALENLKDGDKILMAEGCTHHRQTDDIGTVKIPNMIRKKTGKNITF
                     EFSSGVSFTEDINKYALVVHCGACMMNRAGMLSRIEKAKSFNVPIVNYGVLIAYVKGI
                     LERSLELFNY"
     gene            complement(36746..36997)
                     /locus_tag="KOU88_002302"
     CDS             complement(36746..36997)
                     /locus_tag="KOU88_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-only hydrogenase system regulator"
                     /protein_id="HBK3212176.1"
                     /translation="MKKVAVISAILEEPKECQFKFNEVVSGFKGIIKGRMGIPCEEEG
                     VSIVCIAVVGEMDTINSLTGKLGNIPHVSVKTSISKKEV"
     gene            complement(37378..38418)
                     /locus_tag="KOU88_002303"
     CDS             complement(37378..38418)
                     /locus_tag="KOU88_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBK3212177.1"
                     /translation="MNLNLTNTINLMKKYLDIPSPAGYTENAVLEIKKDFENLGLDTI
                     LTKKGALIATLPGEDDSNQITISAHMDTLGAIVKEISSDGTLKYHKVGGGCWAAIEGE
                     NCTVITRKGKKIRGSVVFKYASTHIYGQTKAATERNEETMIIRLDEKVFTKQDVLDLG
                     ISVGDFVCLDHRFEATESGFIKSRYIDNKSAVAMVLEICRYFKENNLTPKHTTNFYIS
                     NYEEIGHGVSKCLPEKTKEFVAIDIAPTGPSQTSSEHGVTIVAKDNLSLYDFNLRNKL
                     VDVAEDNNLDYAVDVFTFYGSDASEAIRWGEDVQIACVGPGTNNSHHYERTHIEAIEN
                     TLKLLINYMLKE"
     gene            38888..40048
                     /locus_tag="KOU88_002304"
     CDS             38888..40048
                     /locus_tag="KOU88_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBK3212178.1"
                     /translation="MIETGFVYCSFLVVFVGVIFFMVDKLKWKVFDVINPMLLIYLGS
                     AILGSFGLFAQNEDVGTYQNIITVNFLPLMLVFLLIQCDLRKILKMGPKMLLSFFCAT
                     FTFMLGFVIAFIIFKNSMGADSWKILGAASGSWIGGSSNMIAAANALGVAEEGLSYAI
                     LMGSIGYTVWMSVCLMSVKFGPKFNKWTKCDTSFIDEVTSKLEKENKDNTAPTFVELM
                     ILLSVGFGVASFAQIVSKILPTSGILNETMWVVLVASTVSILLGMTKISKLKGSTLVG
                     NVFMYLLLAATGSKANFFGLSEAPVYIMFGLVVVLVHAISFIGLAKLFKLDLFTCEVG
                     SIANIGGVTTAPMIAGVHNPVLIPVGVLMGLLGNIIGTYCALMVTQILHMLA"
     gene            40390..40551
                     /locus_tag="KOU88_002305"
     CDS             40390..40551
                     /locus_tag="KOU88_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212179.1"
                     /translation="MIIPSRRIQDITLTNLKNGEVTLIELDEIYKKMGFLFVVSEGKL
                     KKIKKENHH"
     gene            40744..41373
                     /locus_tag="KOU88_002306"
     CDS             40744..41373
                     /locus_tag="KOU88_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBK3212180.1"
                     /translation="MKIVTYNIHKGMDSNNRLTLTKMGLYLKQLDCDVICLQEVLYPQ
                     FLALKAVLNMDGVFATNVKKVNMIYGICTFTTSKMLNSNHFFLTSKKEQRGALCITID
                     AYGRIINVINTHLGLDRQERAKQLDEIIDYRNRLVGIVILCGDFNEKNVFLSMFNDMA
                     ISLNKSYLPTFEKSNSRIDYIFVNKNTELKGYTVEKIYLSDHYPVIGYI"
     gene            41612..42871
                     /locus_tag="KOU88_002307"
     CDS             41612..42871
                     /locus_tag="KOU88_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBK3212181.1"
                     /translation="MGRRTTRVSRLGKEKKRSVLIVLAALVLIMGGFTYFFNSKFLYN
                     GKIAKNVYIEGVNVSDMTKAEALKGITDKYTPEDLNLAYDGKKYTISPKDIDLKYDTE
                     DVVKDAYESTKKGSYFQNLKKYIDIRVNKANMKIKAEYDEAKLSSKVSSIADSINVKM
                     KNASISVGSGGLSYTDSVVGREFDLAANKESIYNMIKNKEHKTLELKVNLQKPDITTE
                     QVKTVNSVIGQYSTTYSQAVEGRSYNVGLSARKTSDVLLMPGEEFSYNKLTGPSNKAN
                     GYKDAPVIVYGKLEQSAGGGVCQTSSTVYNAALLSGMEITQVTNHSSASTYVPKGRDA
                     TVSDGGLNLKFKNPYKHPVYIKNYAGGGSVSSVIYGNSGDKPNISIEVKQTGQNKYST
                     YRIFKDSSGKVIKKEHISNSSYKELKK"
     gene            43129..44124
                     /locus_tag="KOU88_002308"
     CDS             43129..44124
                     /locus_tag="KOU88_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HBK3212182.1"
                     /translation="MYEEVTWLNFIGNRYEVVNSDDVLEINKIYKARDVFYRKNVLIK
                     VIKHNNYICEDFVSNLIDESTALDEINSPYILKIIDVGIHCTEETTLYYVVSEDFNGI
                     GLDELILGNYLHLEAIVNIMIQVLKALEMIHRNHSYHGSLKSSSIIVDTEYNIKICDF
                     GITKANNGVNTRSYGNRRYLCPHQLCINYTDKESDFFATGLILFESIFKKLPFGESNS
                     EEKMLQSIDKGLDWNSIKAINGNTELINVIKRLLGRNNKYTRANDIIIDLSKVMYEKA
                     YIEVEDEKEEEQKQDKVIQFKKEYKSKMRKKLHKKLVVAGLAIVMISMIIISSII"
     gene            44370..45437
                     /locus_tag="KOU88_002309"
     CDS             44370..45437
                     /locus_tag="KOU88_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBK3212183.1"
                     /translation="MSNIKIIASNKCWIEDIARKQLEDISKLNGILRVVGLPDLHAGK
                     IPVGLAVETKNIIYPHIIGNDIGCGMTLFKTGVLKKKFKKDKWIKSLSKIKDLSDIEI
                     KNTYKEECPILNLGTIGSGNHFVEIQCISEIYNKEQFEQLKFSSDDIMMLVHCGSRNY
                     GEDILKKFYDKDGLEVESEKAIDYIKKHDNALMWAERNREAISKKIMQSIGTSGDVET
                     IFSINHNFIEKREDKFIHRKGAVSSERGAVIIPGSRGSLSYIVMPTENTEISLYSLSH
                     GAGRKWSRSVCKSRLKSKYSKDTIKQTKFKSQIICNDVNLLFQEAPEAYKNIEQIIES
                     LIEYELIQVVATMKPLITYKG"
     gene            45971..47881
                     /locus_tag="KOU88_002310"
     CDS             45971..47881
                     /locus_tag="KOU88_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBK3212184.1"
                     /translation="MNSNTFERLQLNEVKELIKIHCVSSLGKNLIDKLTPSGNIGVVR
                     RKLAENKEARKIIENSNHIPLEGLFNAGSTIDKIEKGMIIEPVELVNIEDFLRGCRKM
                     KAFMLEKEFYSPTLSSYALNITECKSIEDEINYCIKSNKVDSNASKELKKIRRNIEIT
                     EGKIKDRLNKFITSTVNKKYIQEFIISKRNDRYVIPIKSSYKNEVNGTILDTSSKGNT
                     VFIEPISVSNLSTELTMLKADETIEEYKILSYLTELIFEKISQIKLNIEILSEYDMVF
                     AKAKYSQKIKGITPKINNNGYIKIIKGKHPLLTGDAVPLDFEIGKNYRSLIITGPNAG
                     GKTVTLKTVGLLTLMVQCGFDISAKEGSEFSVFEKVFVDIGDNQSIENALSTFSSHIK
                     NIAEIMSLSNNSTLVLFDEIGSGTEPNEGAGLAISLLEEFYKMGCITIASTHYGEIKK
                     FATLHPEFENAGMMFDKETLEPLYKLTIGKSEDSNALFISKKMGIKNRVLDRAKEYVI
                     DRNYNLDLVKRSKLQSNIEDKNSSEVILNYTDYNVGDKVKLLDEDDFGIVYKPMDKFN
                     NVEVLFNDNFISVNIKRLQLSIKASELYPEEYDLDVLFTSFKERKLEKDIQRGSKKAL
                     KKIQKEIRENRK"
     gene            complement(47944..48567)
                     /gene="ytaF"
                     /locus_tag="KOU88_002311"
     CDS             complement(47944..48567)
                     /gene="ytaF"
                     /locus_tag="KOU88_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation membrane protein YtaF"
                     /protein_id="HBK3212185.1"
                     /translation="MIESILLVTSLCIDAFVTSFGYGVNKVKVPLYSNIIISVVCSAI
                     LAISLFAGTIVRDFLPQNITMLICFFILFLLGSARLIESFFKSYFKKKSIHSKNYNFN
                     MLDLKLNFNVSIEPDVLDTSKSKVLKSAEAFTLALALSLDGLAIGFGSGLVGVNYIQV
                     ILFSLISNIIAVLLGCLLGNMFVKNVNLNLSWLSGLILLVIGFMKIC"
     gene            48755..49399
                     /locus_tag="KOU88_002312"
     CDS             48755..49399
                     /locus_tag="KOU88_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212186.1"
                     /translation="MEQNNKVGNFGDLLKILLDEKELSMGELSKKSGIDKSTISRIAN
                     NKQKPNINHLEKMAIHLNINLEELLKASGYEFRNSNNQIFNADSDFSNFDDILGFANL
                     INDKNFNGNIEKELSKCKLYVQTDEGKKLLFDNFNKKIDSIEKQGQFTDRLRQMYADF
                     CTDGLTIKKYLLIGSMLLYFVISTDVIPDFVFPIGFMDDLVALNIVTKLLKNDK"
BASE COUNT        19160 a         5437 c         7993 g        16866 t
ORIGIN      
        1 acggagaact tttaccttct tcaattaata tattattatt agtaataact ttaaaattat
       61 attactatta tataaaaatt ggcttaaaag aaggtgaaaa aagtaaatga aaatatgcat
      121 aacagtaggt catagtatac taaaaggtgg taaaagtaca ggtgtaaatg gtatagttga
      181 tgaatacaat tataataaaa aattagctcc tatgttagct gagatgctta taagtcaagg
      241 taatacagta gatgtaataa tttgtccaga aaggcacttt atgtcagaaa gagaagaatt
      301 tttctataga gttccaaaag taaacagtgg taaatacgat ttattagtag agctacattt
      361 aaataaagct gatggaacac aatgtggtac agaagtgctt tactatggca ctgaaggatt
      421 agaatatgct aaaagagtat ctaatagact tggagaatta tttgaaaata gaggagctaa
      481 aaaaagagaa aatttatata tattgagaaa tacaaatcca gttgcaatac agattgaaag
      541 ttttttctgt gataatgtga atgattgtaa caaagcaaat gaatcaggtt atgattatat
      601 agcacgattg attacagaag gtatattgaa taaagatata aatatgtgag attatggtga
      661 tttaggtatt gattaatacc ttttaatatt agatataaat aaaaatacaa tgtattagta
      721 taatttaaac tttcaaaaga tagattagtt tgattattga caagagatac ctccttgaaa
      781 atattgattt atcagtatat ttaaggaggt atttaaatat aaaaatttaa ttaatttgct
      841 actaaactat aggtttatag agtatatact tttatcttca gtctaataaa taatataaaa
      901 atagtagaac cttgtattat aataatataa tgtagaaaaa tatatagata agataaatat
      961 aataaggtgg taatatatga aatatacatt tgaaaaattt aagttaaatg aaaagatact
     1021 taagtcattg aagagtttag gatataatat accttctaga gtacaaagag aagttattcc
     1081 aaaattatta aaaggtcaaa acttagtagt taggtcaaaa acaggaagtg gaaagacagc
     1141 aagttttgca atacctttat gcgagaatat aaatgtagat tacaataata ttcaagctct
     1201 tatagtggtt ccaacaagag aattagcctt gcaagtaaaa gatgagatat cagatatagg
     1261 gagactaaag aaggtgagat gtagtgctat atttggcaaa caatctataa aagaccaaat
     1321 agctgaattg aaacaaaggg ttcatattgt tgtagctact ccaggcagaa tacttgacca
     1381 tataaataga ggttctatta agttggaaaa tgtaaagtat ttagtaatag atgaggcaga
     1441 taaaatgttt aataaaggtt ttgttgaaca aatggaaaaa atattattaa atttacctaa
     1501 ggagaaaata gtaagtcttt tttcagctac aatagatgaa gagataaaat atatatgtga
     1561 aaaatatatg ctagattaca gtgttataaa tatagaagaa aatgagagcg atactaatca
     1621 aaaaacaaga caaatagatg acaaaataat caaggcaaat ggaagagaga agtacatcct
     1681 tttaaaagaa ttaatataca gcgaaaatcc aaagagtgtg ataatatttt gtaataccaa
     1741 agagaaagta tctaaattat ataacaagat gagtaaagag ggttttttaa taagagagtt
     1801 acatgcagat ttatcacaag aaagaagaat ttttgtaatt aaggatttta aaaaccaaaa
     1861 atttaatata ttagttagta gtgatgtagc gtccagagga atacatattg atgatatttc
     1921 tttagtaata aattatgatg tgccacaaga taaagaaaac tatatacata gaataggtag
     1981 aactgggaga aaaggaaata gtggaaaggc aattactata gtaactgaaa aggatgaaaa
     2041 atatatagag aatatagaaa cgtatatagg atataaaata aatgaattaa aagatataga
     2101 aaaaagtaga attacacatg gcaaagtttt gtttgaagaa tattcaaaag gaatcctaaa
     2161 aaaagtatca aagagaaaaa aagttgataa aaattcttac aaaagtaaag atataaaact
     2221 aaatatagaa agtgaagttg ttaaattata tttaaatgct ggtaagaaga agaaaataag
     2281 agttttagat atagttggtg catttagtaa tataaaaggt ataactaatg atgatatagg
     2341 tgtaattgaa gttcaagatt tatgttcata tgtagatata ttaaattata agggagattt
     2401 gatattaaaa aaatataagg agatacctat aaagaaaaaa atggttaaag tgaaaagaga
     2461 tatacgataa tttagtcaat attgatgaat tgctttgtta tcgaaatgaa gttgcaaaaa
     2521 acacaataga agttgttaag gatttgaaag ctgaagatat gaaacgaaag gtctctccaa
     2581 ttgacttaga aaggattttg gtgactggag gagtaataaa gcatgaagat tctatttggt
     2641 tgttggactt ttgggggaat aaagatattg ctggaatttt gcttatgcct cctactcgtc
     2701 atgttatact tcatttgaat gattgttgta aatggaagga atattttcgt acaaaaaaga
     2761 aattttacag aagttaaatt ataataaatt agacaaacaa tagataaatt agcaaggaat
     2821 gttgatttta tctacattct aagttatact atttttaagt ggctaaggga atagtcattt
     2881 taaatataag taataaatat atacctatag ggatattaaa ggggggaaat atatggcata
     2941 ttttaactat aacgacaaac agtgctacta taatgaaatt ggggatggta caccattact
     3001 ttttttacat ggaaatacag cctcttccaa gatgtttaat gatataatca atttttataa
     3061 agatgaatat aaagtaatat taattgattt tgtaggtcat ggaaaatctc aaatggtcga
     3121 taaattttct gctgacttat ggtttgatga ggctatgcaa gtgatatgtt ttttagaagc
     3181 aatgaactat aaaaaagtaa acataattgg tagtagtgga ggagctcttg ttgcattaaa
     3241 tgttgcactt gagagacctg atttagtgaa taaggtaatt gcagatagtt ttgaaggaga
     3301 agttcctcta gagtcatttg tacaaaatgt gaaaatagag cgtgaagcat ctaagcaaga
     3361 tgatggtgca aaagcttttt atatttataa tcaaggagaa aactgggaaa aagttgtaga
     3421 taatgataca gaagctattt ttgaacatta taaaactata ggaaagtttt ttcataagcc
     3481 tctagaaact atgcaaccag aggtgctttt aacaggaagt agagaagatg agtttgtatc
     3541 tctaatatct agtgattttt ttgaaaatac tttttcatta cttcttgaaa agattaaaaa
     3601 tggtaaaatg tatttgtttg ataaaggtgg tcatcctgca attttatcga atggattaga
     3661 tttttcaaat gtagcaaaga aatttttaga ggaataattt aaccaaaatt tacaataatg
     3721 aaaactgtaa aatggattgc aaaacttaca aaagtgagtg tacatatact tcattattat
     3781 gatgaaatag gattgttaaa acaaaatatt ctaatagtca agttattaca tttgtatatg
     3841 caatatgtat agaaagagat atcattagat tgtaaagttg ggattaaata acaatattaa
     3901 attttattta ttcagatatt ttagcttaac tatataaatg ttagaacaaa ttcatatagt
     3961 taagctgtag gattaaataa tttagttaaa taagtttatt atctcctcat cagatagact
     4021 ttttaataca ccttcattag aaagttctcc atttataaat tgatttataa gctctttttt
     4081 actttcttgt aattttatta ttttttcttc tatagtccct ttagcaatca attttataac
     4141 ttgtactgaa tttttttgac caaatctatg agctctatca ctagcttgat tttctactga
     4201 tggattccac catgggtcaa agtgaattac catgtcagca gatgtaagat ttaaaccagt
     4261 tccgcctgct tttaaagata ttaaaaaaac ttttttatcc atactattat tgaactcatc
     4321 tacaagttca agtctttctt tggcattagt tttaccatct atataatggt atttaatttt
     4381 atacttatca agttccttac ttatgttctt aagcacagaa gtaaattgtg aaaacaataa
     4441 tattttgtgg ttttcgttta tactatccct aagtatttct aaacatgttt caatttttga
     4501 acttttttta ttgtaatctt ttactactat acttgggtct aaacaaagtt gtcttagttt
     4561 agttaaataa gaaaatataa ctattttatc tttctttaga tttttatctt tcattttatc
     4621 ttgtatatct tttgaatata cactatatat ctttttctgc tctttattca attcaacaaa
     4681 aaagtttttt tcaatcttat ctggaagttc tttcataact tgttttttac ttcttctaag
     4741 aataaaaggt tttatcaatt ttttcaggtt tttaacatta tcttctttat ttataaacaa
     4801 ttcctgaaac tttgctttac tatatagata gccaggcatt ataaaatcaa atatagacca
     4861 taattctagt agattatttt ccataggtgt accagtgagt gcaaatttat tttctgcatt
     4921 tatacttttt acagactcag ttactaaagc tactggattt tttatatttt gagcttcgtc
     4981 taatatacaa taatcaaact ttatttcact atatttttct aaatcatttc taagagtacc
     5041 atatgttgta agtattacat caaaattttc taattccata aaacattttt ctctatctct
     5101 tttatttcca tgtatcaata aaacttttat atctggagca aacttttcaa attcattttt
     5161 ccaattataa atgagtgatg tcggtgtaac aataagactt tttttattag ataatgataa
     5221 taaaaatgca atagtctgta ttgttttacc aagacccatt tcatcagcta atataccacc
     5281 aaatttataa taatctaaaa ctttaaacca attgaggcca tttatttgat agtcacgaag
     5341 gtttgcattt aaatttgcgg gaatttctaa atttatgcta tcaaaatttc taaatttttc
     5401 acatatactg tctagttctt ttttaccatc tataaacttt aaatttttac tacgtattac
     5461 atcatttata tatagagctt tatttttatg aattttatta ttttttgatt tatccattat
     5521 atctagattt tcaactaatt caaaaaaatc ttttgtttct ctttctgata aatctataaa
     5581 gtttccatct ttaagtttat aaaaagtacg tttttcttga aaagctttca aaatatcctt
     5641 gtactctttt ggatttatat cagatatatt aaaattaaat tctaggtaat tctggttagt
     5701 ctgattgatt gaagcttgaa ttgatgaagc gttatatatt tttttcaatt taaacttctc
     5761 agaataatat atatctccaa attcctttag agattctaat tgtaaatcta aaaatgtaaa
     5821 taggtcatgg tcagttcctt taaacacata atgattattt tcctttgtaa attgtgaaga
     5881 agtaagttta ttttcaatag tagcttcctt ttgtatgttg gggagcacaa attttttatc
     5941 ttcatcatca tatatatact ttacatcaca acatatgttg ccatcaatca tatcaaagta
     6001 gaactcagat ttaaaatctt ttgttatatt attttttatg ttatcatcta aatgaacttc
     6061 ttgagatata gattttaatc taggaactag caatcctaaa acatccttag aatcctcttt
     6121 atcaaatttt aactctttag tctttgataa tatttgatat atttttgaat aatcatgagc
     6181 ttttttatgt gataataaat agatattgcc atcatataaa agtacatcat tttttttagt
     6241 aagtggaaca ggtagtgaat ctttagaata taagactatt ttatcttcta tatttttaaa
     6301 atcaaacctt acaggtagag tatcatttaa tatctttgga tgatattcct ctttagaaaa
     6361 aataagggta aaatccttgt acttaatagc atttaaaaat tgttttaaag agcttgcatt
     6421 tatctccata aatttttttg aatgtgatga agaaaagttg tatgaaagat ttgtcccata
     6481 ttcttctata atatctacta acttctcatc ttcatcagca aaataatgag tgttggggtt
     6541 gtaagtaaat ttcttcccaa aatctaattc atatccatta agttttgaat atgcaaattc
     6601 agtaatgttt tttaaaatgt acattttatt aattcctatt ttaaattcag caattgcttt
     6661 atttgaatcc acatttatca atacatctaa attaaccctt tctcttttag tattgtctaa
     6721 caaagaaagt aattgcttgc ttaaatctaa gctggtttta gaatttgtat tagaaagctt
     6781 atccttatct gcacctaata tatctattag aataggagga acatcttttt tattttttat
     6841 ttgttttaag ctttttatca caatagcaac tatatgctta catataaaaa tacttttgcc
     6901 ctttgattga cagtcagcgc aactacaatc attttcaatt atcttaaagt gctttatatc
     6961 tatagttatt gaattaaaat aaaagctata attatcttca gaattgactc caccacgaaa
     7021 tgtcaacaga ttattttgta ggtcatcaat atctatgtct atataatcaa ctaattgatt
     7081 agtataatat tttacacctc ttgaccatct tgatggttct gtatttcttc ttattagttt
     7141 atatatcata tctattttca tattattcac cttacctcac tgtatatatt ataatctaaa
     7201 tgcattcaat ttacactcta aatttaagac taaaattaag gcagatatga atagctttta
     7261 tctatcacga tatatgtgta aataacaatt tactattaga tttttattga attatcttat
     7321 aaactatgaa tgaaaaataa ttatataaat agattattaa taaatataaa atcttattat
     7381 taaaaatatt cttagaaatt acactgtata aaatataaag tatgatattt gaataaaaag
     7441 aatgtataat aagtataata atttgtattt attattggga aaggaaaatg ttaatatgga
     7501 tagttataaa caacttaaag ctaaaatacc ctgtaaggaa acaggtatag aaataaagag
     7561 gactttatgt gatatttgtt cgccaggagt acattgtgga attgatgcat atgttaaaga
     7621 tggtaaagta ataaaaatag aaggtacaaa agaacatcca atgaataaag ggttgttatg
     7681 taccaaaggt ctttgcaata gagaatatat ctatagagaa gatagaataa aaacacctct
     7741 aaaaagaatt ggaaaaagag gtgaaggaaa atttaaacca atatcatggg atgaagctta
     7801 tagagaaata gcagaaaaat taaatagagt aaaatctgag tatggagcaa agcatgtagc
     7861 tttttttacg ggttatggaa agtggtatag acctttttta caaaggtttg catcttcatt
     7921 tggttcacct aattatggta cagaatctag ttcatgttca acatcagcac agatggctgg
     7981 aaatgttgct actggaagaa actttacaat gcaagatatg gagaatgcaa aaacttattt
     8041 agggtgggga tttaatccat actactctaa atttttaaat agtgtgaatc taataaaatt
     8101 aaaagaaaaa ggtctaaaat ttataattgt agaccctaga ataacaccga caactcaaaa
     8161 actagcagat ttacatttaa gaattaaacc tggaactgat ggagctttag ctcttggaat
     8221 ggcgaatcta tttatacaaa aggatttaat agatagagaa tacatagaaa agcatgtaca
     8281 tggatttaat gaatataaag aatatgtaaa attatttgat ttagatactg taagtagaat
     8341 tacaggagtt tctaaagata atatagtaaa agctgttgag atgttgtcac aaggtccatt
     8401 ttgtataaat gaaagtgcag ctccaatagt tcaccatcaa aatggatttc aaaattatag
     8461 agcaatgatg tctttatccg ctataacagg taattatgat agaataggtg gaaacatacc
     8521 aaaacaagat tactttgctg gtaagatagg tggattccaa acactagaaa aagagtttgt
     8581 aaaagaagtt ctacctaaaa atataaatga aagaattggt ggagaaagat ttcctctatg
     8641 gaatgaaatg gtgactcaat ttcaagctat ggatttacct aggcaaatag aagaaaagac
     8701 accatatgaa ataagagctt tgttttgtca tgggataaat gctagaatgt ttcctaattc
     8761 agggagactt tttaaagcgt tgaatagtgt agattttttt gtgaatatag atttatttat
     8821 gacagataca tcaaaatatg cagatatact tttacctgca tgtacatcat ttgagagaga
     8881 agaatgtaag agttatccag gagggtatat tacatatacc aaaaaagtta ttgataaatt
     8941 atacgattca aaatcagatg tagaaatact ttcagattta gcaaatgcta tgaatataga
     9001 tgatgattta ttaaaagcag gttatgaagc aagtgtaaga catatgttta aaaatacatg
     9061 tgtagatgta gataaactta aagaaagtga tttaccatta aaatgtaaag attttaagcc
     9121 atatatagta ggttcatata caagagaagg gtatgatact agcacttcta ggtttgaatt
     9181 aaaatctaca attattgaaa aatataaaga ttttgggctg gatgcactac caacatatag
     9241 aggatttaat gataatatag atgatgaata tactcattta ttgacatcag gagcaagaat
     9301 ttcaaatgca ctacattcaa gacttcatga catcaaactt tcaagaatat taaaaaatga
     9361 agctagttgt gatatttcta gcttagatgc aaaagaattg ggtgttatca gtggagatta
     9421 tataaaaata actactaaga taggaagttt ggatgtaaaa gtcaatgtta ctgatagagt
     9481 cttatataag aatatacata tgtatcatgg atatagagaa gctgatataa atagtattat
     9541 ttgtgataat tttgaccctt atagtggatt ccctgcgtat agaagttgta agtgtaagat
     9601 tgaaaaaatg aatagataaa tggagagata taatgaaaag tttatttaaa tttaataaag
     9661 aattatgtac agcatgtgga gcatgtttgc ttgcatgtat agaccaaaat gataataata
     9721 tagacaatgg tgaacttttt agacatgtat ttacaataga ggaaggtgaa aatatagaat
     9781 atttttcatt agcatgtata cattgtaatg agccaaaatg tttaggtgta tgtcctaaaa
     9841 attgttttaa aaaagaagaa ggattcgttg tattagacaa tcaaaactgt atagggtgta
     9901 aactttgtga aaaagcttgt gaatatggag ccttaattta tggaaatgat ggtaaggcaa
     9961 ataagtgtaa tggttgtatt gagagatata agtgtggtat ggattcacct tgtgtaatgg
    10021 tatgtcctac aggagcatta aaatttaata aataaattaa atatagagaa tgacttatac
    10081 ttaggtataa gatattttta caaaaagctg tattgagttt gttataatga aaactcaata
    10141 tagctttttt atggatatag ttggatacta taatgtgatt cttagtaata gttttttgct
    10201 attggacaaa gactgtaaaa catattaaac ttatgttgtt caaagtcgaa gtataatata
    10261 ataactagaa aattggttta tagtgctata aaagcaaatt tagtaaggta taaaatcaga
    10321 ggcaatcctt tactataata tcaatatttg ggagttctgt tattgcagag ctattaaaca
    10381 attataatgg tacaagtgat tcaacctttg aaaatgtatt atataaaaaa ttaaaataag
    10441 attaaaaagg agagaataaa ttatgaaaaa acttaaatta attattatgt ttgccttggt
    10501 atcagcactg ttagttacag gatgttcatc aggaaataat aaaaataaag aagaacaaaa
    10561 agttataaga gttgcaacat caggaacata ttaccctttt gcttttaaag ataaagataa
    10621 acttaaaggg tttgaagtag atttttggga tgaatttgct aaacgaacta attgtaaagt
    10681 tgaatgggta ttaactgatt ttagtggatt atttggatta ttagaagctg ataaagcaga
    10741 tgttgtatct gctcaactta ctgcaacacc tgaaagagag aaaaaatatg ctttttcaga
    10801 tgcttataat tatagtggaa caaacattat tgttagagaa gatgatacta gtataaaatc
    10861 aatagatgat ttagttggca agaaagtagg tgtgggtact ggagcagtag caaatgaaat
    10921 attaaaagaa aaatacccaa atgatgaaat aaaaatagta aattattcaa gtgcgactct
    10981 taaagggaat tatcaagacc tagaaatggg aagattagat gcagtagttg cgcaggatgt
    11041 tgaggcttta atagctataa aagaacaaaa attaaatctt aaaatgatag aacctccaat
    11101 tcaatttggt gcctgttctt ttgcgcttca aaaaaatgaa aaaggtgaaa aatggacaaa
    11161 agaaattaac gaagtaattg aagagatgta taaagatggg actttgacta aaatatctga
    11221 aaactggcta ggaaaagaca ttactaagga gcctattaat gagtaatttt aattttgaat
    11281 tttgtctaag tatatttcca tttttgatta aagcattggg aataacaata ctaatatcta
    11341 ttgttgcatt ttttttatca atattattag gtgtaatact tgcctttttc acacagacaa
    11401 aatcaaaagt tttacaatac ataacaagag tgtatgtttc attctttaga ggaacaccac
    11461 ttttaattca aatatttttc ttttattttg gatttccaat gatattttct tttatgaaag
    11521 attgttcacc ttatttagca atagtaattt gtttaggtgt aaattcatct gcatatatgg
    11581 ctgaaattat acgagcatct attgagagtg ttgataaagg acaacaggaa gcatgttatg
    11641 cttttgggtt aagtaaatat cagtcaatgg ttaaaataat tctacctcaa gcagctacat
    11701 ctgcagtacc tcctattgta agctgtacac tggacataat taaaggttct tctttaggtt
    11761 taactatagg aatacaagat ttaatgggag tagctcaagt agaggctgct tcaagtttta
    11821 aatattttga gatatatatg ataacgatat taatttactg ggcagtatct ataatattga
    11881 gtaatataca aagcaaagtt gaaaaaagaa taagaagagc atattagatt tcaatattta
    11941 aaaatgggat gatatagata tattattact tgtaaataaa tttttaattt tagaaaaata
    12001 aacttagtaa tctaaattat tgagaaaata tagtatcaaa atggactgta taatcaagtt
    12061 aaaaaatagt ttttctattg aaaaaataaa taaaattcta ttgtaattta atatgcgata
    12121 aagttttata aaaaacaaca ttaagctagg gggacttatt ttatggcttt taatatgaaa
    12181 tattttttag aattatttcc aacaataatg aaatcgttca atgtaactgt gattttggca
    12241 ataagttcat tagtattttc attaattata ggtacaatag tagcgttatc atcttattac
    12301 aaagtgaaag tattgaatca aatatgtaaa gtatatgtat ctatttttag aggtacacct
    12361 cttatgccac agttattctt tttatatttt ggactagcat atatgagtga ttttgttaaa
    12421 aatatggacc cagtatttgc aacatctata gtacttagtt taaatatggg agcttatatg
    12481 tctgaaacga taagggcatc tatactttca attgatacag gtcagataga agcagcatat
    12541 gcaataggat taacaaattt acaaacaatg aaaaggatag tgataccaca ggccgtaaga
    12601 gttgcactgc catcattatt caataatttt atagatttaa ttaaagggtc ttctgtagct
    12661 tttgttgttg gagtaaatga tataatgggt gctgccaaat cacaaggagc gttgagtttt
    12721 aagttttttg aagtgtatgg agcagttatg gtaatttact ggtgtataat aactccttta
    12781 ggttgggggc aaaaaaaatt agaaaagaaa ataagcaatt attaagttat taagaaaata
    12841 cataaaagta tttttatata aaaaatggtg tgaggagaag agatatgata aaaagaaata
    12901 ttataaaatg tttagtggca gttttatcgt taacgtttgt aattactggt tgttcaaaaa
    12961 aagaggaagt aaagaatgaa aaagttataa ctgtagcttc atctaattca gctgacccat
    13021 attcttatgt tgataatggt gagcataagg gttttgaagt tgacatgtgg aaagagattg
    13081 gtaaaagaag tggatataag ataaaaatgg aaccaacagg ttttagttct atatttggta
    13141 tgttagattc tggtaaagtt gatgtggcag ccaacttctt tggaatgtct aaagaaagat
    13201 tagaaaaata cgatgcttct ataccttatg gttctgattc tgtgtgtata gctgtaaaag
    13261 atggaaataa cgaaattaat aagcttgaag atttaaaggg aaaagttgta gcagtttcag
    13321 aaggttctca aggtcaacag gttgcaacta gtgttaataa agataatttg tttcaagaaa
    13381 aggtttacgg tgatggaact agtggtcttc aagatttaga tttgggaaga gttagtgcat
    13441 ggattgatgc agagcttact attgtgggag acgctaaaaa agctaatatg aaagtaagag
    13501 tattagataa aaaattatca gctactaata tagcatactt ctttaagaaa aacgatgata
    13561 aatctaaaac gataaaagaa gatgtaaaca aagcaataga agaaatgctt gcagatggaa
    13621 cagtgaaaaa aatatctgaa aaatggtttg gaatggatgt aagtgctgat atacaaaaat
    13681 aaatacttta aaattaaaat gtaaaactgt gataactata gataagtata ctaaatttat
    13741 ctatagttat ctgtgtatta caatgtattt agattagtct ttataaatca aaatgagtta
    13801 tggaggtatt gcaaatgatt gaaactaaaa taaaatccat tgcactaaaa aatagagaaa
    13861 aaattataaa aataagacga cagatacaca gtaatccaga gttagcattt aaagaatata
    13921 aaacatctaa acttataaaa gaagagctaa ataaacttaa tatagaatac ataaatattg
    13981 ctggtacagg agtattagct actataaaag gaaaaaataa tggtggaaaa actatattac
    14041 tcagagcgga tatggatgct cttccaatca aagaggaaaa tgatttagaa tttaaatcaa
    14101 taaatgataa tatgcatgct tgtgggcatg atgcacatgt ttcatggttg ttaggaacag
    14161 caatgatttt aaatgacata aaagaagaat tgaatggaaa tgtaaaatta ctatttcaac
    14221 ctggcgaaga aaaaggtggt tctgatattg taattaaaga aaatgtactt gaaggtgtgg
    14281 atgcattagc gactggtcat tgttggccaa ctattgagtc aggaaaaatt ggaatcgcta
    14341 gaaattgtgc tatggcagcg actaatactt ttgaaataac aataattggc aagggtgggc
    14401 atggagcaga gcctcataat tgtatagacc caattgcagt tggaaatgca gtatattcat
    14461 ccattcaaca gatagtttca agaaaaattg acccagttgt acctgtagta gtgtctgttt
    14521 gttcttttaa ttctggtgtt tctaaaaata taataccaga tgtatgtaca cttcaaggga
    14581 ctattagagc gataagcaag gaacaagtaa ttgaagtaag taaaattcta gaatatatag
    14641 taaaaaatgt atgtaaagca catggagcag attgcaaatt tgaaaagagt acaggaggag
    14701 atgctgttat aaatgacaaa aacatgatag agataggaag agaaagtgct tgcaaaatac
    14761 ttggagctga aaatgttgaa ataattgatt ttcctgcaat gacaggtgag gattttgcta
    14821 tttatatgaa agaaaaacct ggtttattta tgtatatagg tgtaggagat aaagaaaaaa
    14881 atataaatta cagattgcat agtaacaagt ttaatataga tgaaaaatgt cttagtatag
    14941 caccttcatt attttcacaa cttacagtag attatttatg tcaactatag agtacattca
    15001 taaaaatata tttagcctat ttttaaattt aatgctagta tattaatttt gatgtagaac
    15061 atattattta ttatatttat ttaaaaaggt ggataacaat gataaaagta gaaaatttac
    15121 ataaaagttt taaagggaca gaagttctta aaggtataaa tttagagata agtcaaagtg
    15181 aagtagtagc tatacttgga tcatctggaa caggtaaatc tacgttactt agatgtttaa
    15241 attatttagt tgagcctaca aaaggaaaga taatgattgg tgatgtaaaa gtagatgtag
    15301 aaaaagcaac aaaaaaagat ataaccaatt taagaaaaca tacatctatg gtgtttcaaa
    15361 attataactt atttaaaaat aaaacagcat tagaaaatgt aatggaggca ttgatagtag
    15421 ttcataaaaa gagtaagaaa gaagctagag aaatatcttt aaaattaata gataaagtag
    15481 gtatgttgga taggaaagat ttttatccat caaagttgtc tgggggacag caacaaagga
    15541 taggtatagc gagagcgatg gcagtaaatc caaatgtaat attatttgat gagcctacat
    15601 ctgcacttga cccagaactt gttggagaag ttttaagcgt tataaaatct cttgcaaaag
    15661 aaggtataac gatgcttatt gtaactcacg aaataaattt tgcaaaagaa gttgctgata
    15721 aaattatatt tatggataat ggtgtaatag ctgaagaagg aactcctgat gaaatattta
    15781 ataatcctaa aaatgaaaga acagcaaaat ttttaaatat cattaggaaa gaagaagtat
    15841 ttagttaaaa gtgtataaat taagcattag aagatatgta agataccccc attaaattta
    15901 taagttagat aataaattta atgggagtat atttttatta ttagatttat tatttaattt
    15961 aaaattagaa atgtaactat ttgaaaattc tttttaaaag tatatcaaaa tatcaaatac
    16021 ataaaaaaat aatatttgac aaagtatcat atgtgtttac aaaatcaact ttatggagtt
    16081 atatagtata ggaattacaa tgaatatact aaaattttat attaaagtac aaagtattaa
    16141 atttgaaaat aattaagtaa tattatatat atttttttat attgtttgtt ttattaaaat
    16201 taatctagaa aaaaagtttt aaaagcagaa ttttattaat atttatatat agatatgaac
    16261 tattaataaa acgttaaaaa tacaaaaaaa ctatagaaat tgacatatat tccagtattt
    16321 gctaaagtag ctgttgggga aaattacaaa aattattaat gcgcattaga taatttgctt
    16381 taattttttt agcatttggg gtaatttata atataaagca ttagaaagga aaatataaat
    16441 gagggacttt ttaaaaaatt ataagtcatc aattatactt ttagcatgta ctatagtagg
    16501 ggcgatagta ggattagtac ttggtccaaa agcttcaata ctaaaaccat ttggagattt
    16561 attcataaat gctctattaa tgatagtagt accattagtt tttcttagtg tttcttcagg
    16621 tgttgctagt ataaaaaata tggaacgatt tggaaaaata atgaagggta cagctatagt
    16681 atttatggga acaacacttg taattgcatt tttaggtatt acatctgcat tattatttaa
    16741 tccgtctaaa ggattagatg tatcaagtgt aaaaaattta atggtggctc aagatgcaga
    16801 aactttagaa tcaaaaggaa cgttattaga ccaagtagta tcaagtatta cagttaaaaa
    16861 ttttggagat ttattttcca gtagtaattt actacaatta gttatatttg cagttttaat
    16921 tggaacagca atagctatga tgggagatag gggaaataca ataagaaagc ttttatcaga
    16981 aggaacggaa gcaatattaa aagtagtaag tatattcatg ctttatgctc ctatagggct
    17041 aggctgttat acagctacaa taattgggga acttggaagt aaaataattc aaggatatgt
    17101 aagggtgttt gtaatttatt cactaacagc agccatgtat ttcttattat tttacagtct
    17161 gtatgctttt ttatctgcag gaaaacaagg gtttagacaa ttctggagaa atgctataaa
    17221 accaatagca acggcactag ctacttcttc aagttcagca tgtataccat caaatttaga
    17281 agctagtaaa aatataggag ttcctgatga tatatcagaa acagttatac ctcttggaat
    17341 aaatatacat aaagatgggt cagttttagc agtaataata aaagtggcat ttttatcagg
    17401 tattttaggt agtggaatgg caaatccagc aacgataggt caattattta taactgtatt
    17461 tgttgttgga gtatttatgg ctcctgtagc aggtggctga cttattggtg agatgctcgt
    17521 ggttagcatc ttcggttttc cagtggaggc aattccactg ttaacagtta taactactat
    17581 aactgatatt cctaatacta tattaaatac aactggaaat acagtatcat caatgttagt
    17641 ttcaagatta gtagaaggaa aagattggct tatagataaa acagcaatta ctacaaagaa
    17701 aataagctaa ttgtacactt aattaataaa gttaataggt atcttaattt taataaatta
    17761 gatacctatt aactttttaa gtaaaaatat aaatttaaga ttcaaatatg atatttataa
    17821 tttgaatcaa ctaatatagt atatattgaa ataaatatgt ttaaatatct attttatttt
    17881 ttaaaataaa agatttcaaa tttatttttg ttaaaagata acaagccttc atctcgcatc
    17941 ttgccaagct ctcttgacat agaacttctg tcaacacata aaaaatcagc catttcattt
    18001 cttgaaaagg gaattgtaaa ctggtggcta cctgtttgtt ctatctgttt tgaaaaatac
    18061 ataagcaatt tctcgcgagt tgttttacga gaaagtaatt ctattttatt gtgaagtaaa
    18121 atgttttttt cagctattaa ttgtagcata ttttcaacaa gcctattatg aaatacacat
    18181 gcagatgaac aaataccagt tacactttta aactttataa ataaaacttc gcaagaagat
    18241 gttgtggtta ctgtaacatt acttttatgt agtctagtac atgcgaatac ctctccaaat
    18301 aaatctccag gcaagagttc agctacaata ttcctattcc cttcgatatc ttcctttatt
    18361 atatgagcac ttcctttaag cataattcca atagaagtaa cttcacttcc aacagagaat
    18421 attatactat cttttgggta agtcttatct acaacaccta aacattccaa catttcttca
    18481 agttcatcac ttttaattcc ttcaaataga ggaatttttt taagtaggtc tatatgcttt
    18541 tctaaaaatt ttttcaaata atcacttcct tgttgcatat gcaaccgata atttgttttc
    18601 attgtactat actaagttta taaaagcaag gggatataaa aatcctacta caagaaattt
    18661 gaaataaaga aatataggta ttaaaaataa atatataaga aatcaatact ttaaattaaa
    18721 aaaattttat gaggtgatat aaatgatgag aaaaataatt aaaattgatg aggaaaagtg
    18781 taatggttgt ggactatgtg ttgaagcttg tcatgaagaa gctataggaa tggtaaatgg
    18841 aaaagcaaaa cttttaagag atgactattg tgatgggctg ggagattgtc tgccaacttg
    18901 tccaacaaat gcgatttcat ttgagtatag agaagcagca gaatatgatg aagctgcagt
    18961 aaaagcaaat atggaagcaa agaaagcaca aaagaaaact ttagcatgtg gatgtccagg
    19021 ttctcagtct aagtcaataa atagagaggt ttcaaatagt acgtctataa gcaatgatat
    19081 agtagagata aaaggttctc aacttaatca atggccagta caaataaaat tagtaccaac
    19141 taatgcatca tatttaaaga atgcaagtct tttaatagca gcagactgta cagcgtatgc
    19201 atatggaaat tttcataata aatttatgaa aaataaggtt acattaatcg gatgccctaa
    19261 acttgatgaa gttgactatg ctgaaaaact tacagagatt ttaaaagaaa atgatattaa
    19321 aaatatagta gtaacacgta tggaagttcc ttgctgtggt ggtatagtaa atgctgttaa
    19381 gacagctcta caaaatagtg gaaaaatgat accatggcaa atagttacta tatctgtaga
    19441 tggaaaaatt gtagatggag aaatttaatt aagtgaatta tagaaaaata taataaattt
    19501 taataaataa aaagggagga ataaaaaatg gaaaaaatgt tttgttttca atgtgaacaa
    19561 acagcaggag gtaaaggttg tactataaat ggtgtctgtg gtaaaaaggg gggtacagct
    19621 aacttacaag acgaacttac aggagtgttg attggtcttt caagagcaac tattggaaat
    19681 aagaatagac caacaagtga aacagataaa attatgatag aggggctatt cactactata
    19741 acgaatgtaa gttttgatga tgaagctata aaaagacaaa ttgaaaaaac tgaggtagaa
    19801 aaaagtaaac ttgtacctag atgttcagat tgttcaacaa cttgtaatag aaatgataac
    19861 tatgatatga aggatttatg gaatgataat gaagacatac gttcattaaa atcattaatc
    19921 ttatttggat taagaggtat ggctgcctat gcatatcatg caatggtact tggttataca
    19981 gacaaagacg taaatgaatt tttctatgaa ggattaatag cagttggagg agacttgtct
    20041 attgacgaac ttttaggtct agttatgaaa actggagaaa taaacttaaa atgtatggaa
    20101 ttgcttgata gagcaaatac tgaaacttat ggaacaccag aacctacaca ggtatctatg
    20161 aaaatcgaga aagggccatt tattgtagtt acaggacatg acctttatga tttacacaaa
    20221 ttattagaac aaacgaaaga taagggtata aatatatata ctcatggtga gttattacca
    20281 gcacatgcat atccaaaact aaaagaatat aaacatctaa aaggtaattt tggtacagca
    20341 tggcaaaacc agcaaaaaga atttgataat attcctgctc caatattatt tacaacaaac
    20401 tgtttaatgc ctgttaaaga tagttataga gatagagtat ttactacaga agtagttgct
    20461 tatccaggta tggttcatat tgatgaagat aaagattttt ctagtgtaat agaaaaagct
    20521 cttgaacttg gaggatatag agaagatgtt catatgactg gtattaatgg aggagataca
    20581 ttaactactg gttttgcaag aggtacagtt tcatctgtac aagataaagt agtagatgct
    20641 gtaaagagtg gagctataag acacttttta ttggttggag gttgtgatgg tgcaaaacct
    20701 ggaagaaatt attacactga atttgtaaaa caagctccta aagacactgt tatattgaca
    20761 cttgcatgtg gaaaatatag atttaatgat ttagaccttg gggatatagg tggcttacct
    20821 cgtttaatgg atatgggaca atgtaatgat gcttatagtg caattaaagt ggcagtttca
    20881 ctggcaaatg cttttgaatg tggagtaaat gatttgcctc ttagcatggt actgtcatgg
    20941 tatgagcaga aagctgtttg tatacttctt acactacttc atttaggtat caaaaatatc
    21001 tatataggac cttctttacc agcattctta tctaagaatg tattagatat attggttgat
    21061 aaatttgcat tgacacctat atctactcct gaagaagata tgaagaagat tttaggataa
    21121 ataaatatat ctatacttaa agatatttat agttaaacta tttttaagta tgccacaatt
    21181 aagataaggg gttaaactta aaatttgatt aaaaaatcaa ttttgagatg accctttatt
    21241 tattttttgt aataattgaa aaataaacct gctttcagta tatttttttt aagaatcttt
    21301 gtattaaatt tataatactt agatatataa tatcttatat attttatttt aagtattaaa
    21361 ggtttgaatg taacttaaat attaaaagag gaacattgta atatgtaact tgcataaaat
    21421 atatatacta tagtgaaatt attttgatta aaatttaaaa tataaggtgt tttatgtggg
    21481 ggtatatgta tatgaaaaat tctaatttta atatattggc atttgatggt ggtggattaa
    21541 aaggggcatt gagtatatcc atacttgaga ggatagtaaa agagtatcca aatctattaa
    21601 acaatataaa tatgtttgga ggtacatcta cagggagtct aattgcacta gggcttgcgt
    21661 atggtgtaag ccctaaagag ataaaagaac tttactcaat tgaaaattca aagtatattt
    21721 ttaataaaag ttatgcagaa atactcagac caaagtatga aaacaaaaac ttaaaagaag
    21781 ttttattaag tatatttcca gaggaactag aattaaaaga tttaaataaa ttagtaatga
    21841 taccaagttt ttatatagga aatgaggaaa atgcatggaa accagtgttt tataacaata
    21901 tgccaaattc ttttacaaag actagcaaag ttgtagatgt agcaatggca agtagtgctg
    21961 ctccggtatt ttttccaaca tataatcgtc atgttgatgg aggaataata gcaactgacc
    22021 cgagtttagc gtgtataatt catgccattg acagtggatt taaacttaaa aatacaagac
    22081 ttttttcaat agggactgga tatgtatata acagtataaa ggcagatact actgaatggg
    22141 gagctattga ctggataatt aataaagaac ccgatttacc aattatatct attaccttag
    22201 aaggaaattc tcaaatgagt cagttatttt ctcaaaaact tcttggagat aattactata
    22261 gattaaatcc taagatggaa aaaaatgtag ctatggatga ttgtgatgca ttagaatatc
    22321 taatgtcttt aggagaaaat tgtgatataa aagatgcttt tggatggata aagaaaaaga
    22381 gcttttatag aaattagatt caatttgcaa ttgtattttt acacatgatt tcattgagta
    22441 ggtaaaaata ataaaatgca gattattaag ttacttctta gggaataaat aaagtataat
    22501 ttatttaagg agtgatgaaa atgataaaac ttgctacttt tgcaggtgga tgtttttggt
    22561 gtatggtaaa accttttgat aagtatgatg gagttattaa agtagtttct ggatatacag
    22621 gtggtcatgt tgaaaaccct acatatcaag aggtatgttc aggaactact ggtcatttag
    22681 aagcaattca aataacatat gatgatgata taataagtta tgatgaactt ctaaatatct
    22741 tctggaaaca gattaatcct acagatgatg gtggacaatt tggtgatagg ggaactcaat
    22801 ataagactgc tatattttat catgatgaag aacaaaaaaa tatagcttta gagtcaagag
    22861 aacatctgga aaatagtaaa atatttgata gtaaaatagt gactgatata attccagcaa
    22921 ctaaattcta cgaagcagaa gaaaatcatc aggattatta taagaaaaga ccattaaact
    22981 acaatatgta ttataaaggg tccggaagat ataattttgt aaaaagtcat tgggatggaa
    23041 acaatataaa tagggaagag ttaaaaaaga ctttaactcc tatacaattt gaagttactc
    23101 aaaatgatat gacagaagta ccttttgaaa atgaatatta tgacaataac aaagagggaa
    23161 tttatgttga tattgtaagt ggagaagtgt tattttcttc aaaagataaa tttgattctg
    23221 gatgtgggtg gccaagtttt tcaaagccag ttatagataa atctatcatt gagagaagtg
    23281 atttctcaca aggtatgtac agagttgaag taagaagtgc taaaggaaat tttcatttag
    23341 gtcatgtatt tgatgatggt ccaaaagaac ttggaggttt aagatattgt ataaattctg
    23401 cttctcttaa atttatacca agagaaaata tggaagcttt aggatatgga gaatatttaa
    23461 aactttttga gtaattagga atatttatta taaacttatc taaaaggtga aaatctaaaa
    23521 aaatattttc accttttgtt tttttgtcaa tagtatgata aattattaat tgtaatctta
    23581 tttataccaa tagattaaga atttaatttt gaaagagaga aaacaaatga atttaaaaga
    23641 ctttaatgga aagagattaa aatcagctag aatttttaga gcaaagacga tagaacagtt
    23701 gtctaaagaa actaaaataa ataaaaaaga tttaaaagct tttgaggaaa ataagtatgt
    23761 accaaatata gaaaatacat taaaattatc taatatatta aattttccaa aagagtattt
    23821 ttataaaaat gaaaatataa atatcgttgt agaggatagc cactttaacc ctcaatctaa
    23881 actacctaga gtagaagaga tttcttatag agaaaaaata attataatac ataaaatata
    23941 ttcatttatg gagaattata ttaagtttcc aaaagaaaac ttgccaaata gaaaagtaat
    24001 gtcagatatt aatataaatg atatagaatc tcttgcatat aagactagag agttttggga
    24061 tttaaatagt actccaatag taaatatggt aagtttgtta gagtctaaag ggattataat
    24121 atcaggtatg aatgtagata gaaaaggggc aactatcttt actcaaaaac agagaattag
    24181 taaagaatct aaatatctaa tatctctggg taatgacaaa aagtcagcat caattagaaa
    24241 ttatactttg gcatgtgagc ttggatatat aatatcaagt gaattaagaa taccaagtaa
    24301 gcaattttca gaagatgagt atgcctgtgc atttttattg ccaaaagaga gttttttaaa
    24361 agatttgact catccagaag atttagatta ttatgtagaa ctaaagaaaa aatggattgt
    24421 acctatatct gctatgattt ttagagcata taatctagaa aagataaatt acaaaaaata
    24481 caattatctt atgaatgaaa tggataaaaa aggctggttg atagaagaac cactagacaa
    24541 aatgaaaggt tcaagcccaa cgtatttaaa aagagcagtt gaattattga tagaaaataa
    24601 aataatgagt gtaaatagta tagtatcaag tttagaggaa tttggaataa atctttatcc
    24661 agaagactta gaattattga tgggattgaa aaaaggattg ttatctcaag aggtaaataa
    24721 aaaaagtaaa gttataaaat ttgatggtaa aaaataggtt tatattttag tattaaaatt
    24781 aaaagcaggt acaaatgatt taaacattaa cttagttaaa agttttttca ataagtcatt
    24841 tacctgcttt tagtgtaaga aagaatattg aatctaaagt gtttttgaaa gtgcaatata
    24901 ttcccttaaa acagaacaag atttattaaa ttcgttttgc tcatattcag tcatattgat
    24961 ttcaataatt tcttcaatac catcttttcc tataacacat ggaacacctg caaatacatt
    25021 tctttcgtta tattgacctt ctagtaatgt agaaactgga agaacttttt tctcattgtg
    25081 tagtatagct tttacaattt ctactaaagc agtacctata ccaaattctg tacaatcttt
    25141 accatttatt atacttattc ctgttttttt atttttttca actattgatg gtaagtctaa
    25201 attgctataa gtacttgggt tgtcttttat catgtctaag attggtttac caccaattga
    25261 aacatgagac caaggaacca tttgagaatc tccatgttca cccatagaat aagcttgaat
    25321 tgattgttga gcgattccag tttcttcaga taaaatcctt ctaagtcttg ttgaatctaa
    25381 agctgttcca gttccaatga ctttgttttt aggaaagcca gatttttccc aaatataatt
    25441 tgtaactaca tcaacaggat tagatatgac tacaaatata ccatcaaagc cagaatcaac
    25501 tatgggtttt actatagatt ttatcattcc aatagttggt cttagtaaat ctaatctagt
    25561 tgtgttttgt ctacgtaaag gcccttctga agagtctgca acacttatca ctactatgtc
    25621 agaatcttta cagtcagaaa aagttccttt ttctatatgt actttatgtg gcagatatga
    25681 aactgcatca gctaaatcta aagcttgagc ttttgattta gattcatcta tatcaatcat
    25741 aaagagttca tcacaaactc cttgagttat taaactaaat ccacaatgag aaccaacatg
    25801 ccctgaacct acaatagata tttttcttgg ctttattgcc attttaaatc actcccccta
    25861 aaataacgat acattgaaaa ttatagatgt tattaaaagc tgtttttgaa tattttaata
    25921 ttctattatt tcagaaaatt tatttaatat gattttatac taaaattttt aaaaaagcaa
    25981 tgttaatata ctctctatta gtgaatatta aagtattata tgtatattaa taattattaa
    26041 aatatgtaat gtcactgata gttagaatat ttaagtgcta aaagatgtgt ataaataata
    26101 atgatgtcag cttataatga tattaaattg agatatactg tttctctaaa ttaaaaaata
    26161 aaggagtaaa tgtgttatga attatcatac aaaagaagaa ttggtggaag cactgagagt
    26221 agtatcttca agtattatta attgtggaaa aggacagaag aaattttctg aggagacatc
    26281 tcatcataca tgttttaaga atattataga agtaatgtat atttcaaaat cattaataat
    26341 ggatgaaatt agtaaaagag attgaagctt attttgcaat ttaacatgtt ttaatataca
    26401 ttttattata taagaaaata agtaaacata catgttataa aatattggaa taatatacaa
    26461 ttataaattt gttaacacta atatctatat gttaaaatat agtagaagat gttagtaaat
    26521 aataggatga gttctatttt aatacaatta aattaagctt agtttgaaat ttgtatctaa
    26581 aaagtaaagt aatctagaat taagaaaatg gagatagaat tataatggaa aaattatact
    26641 atacaaatca gtatataaga gattttacag cagaaataat tgaaataaaa gaagtagaaa
    26701 ataagtatca tgttttatta gataagacag ctttttttcc tggtggagga ggtcagtttg
    26761 gagacctggg aaaaatagag aatgatgatg taataaatgt gtatgaagat ggaaaaaaaa
    26821 tataccatgt attagataaa aaacctataa agatacataa ggtaaagtgt agtattgatt
    26881 gggatagaag agaagatgga atgcatcaac attttggaca acatgtattg tctggatgtt
    26941 tttttaaaac ttttaatgca aatacgacag gttttcattt gggaaatgag tatagtacag
    27001 tagatataga aggtaattta gaagaggata aaattagaga gatagagttg tttgccaatg
    27061 aaattattcg tcaaaatata caagtagaga cattacttcc aacgaaaaaa gaactaaaaa
    27121 agatttggtt aagacgtgat ttgccaaata ctgatgaaga gataagagta ataaaaatag
    27181 gtgatttaga tacgaatgca tgttgtggag tgcatccaaa atcaactggt gaattgagaa
    27241 tgataaaaat aaagaaatgg gaaaaacata agtcaagtac aagaatagag tttctagcag
    27301 gtaaaagggc agtggatgaa gtattgaaga gggatatata tttgactaaa atatgtagat
    27361 atttaagctg tagtgaggaa gatgctataa atggtattgt aaatctaaat agtaaagtgg
    27421 aagaggcttt aattaaaaaa agaaggcttg aagaagtagt atctacatat caggtcaaag
    27481 aaatgattga aaaagcaaat aaggttggca atatttcggt cattaaaaaa atttatgatg
    27541 atgaagattt gaaatatgta aataagatag caaataaaat tgcagaatat gaaaatagta
    27601 ttgcattatt agctgttaaa tttaatgata aaataaattt agtttttgca tgttctaaaa
    27661 atttaaaaga tattaatatg ggagttttat taaaggatgc aataaatctt atagatggca
    27721 agggtggtgg aagtaaagta ttagctcaag gaggaggtaa gaataatgga aatttagagg
    27781 ctacacttga ttatgcattt atgaagatag aaaaaactct ataaatatat tatataaaaa
    27841 accttagtag ataaaataga tatggaggaa taagtatgga gcaacaaaag gactacatag
    27901 agttatatga aaatgaagaa ctaatagaga taagagaagc acgtatggat gatttggata
    27961 caatagcaaa atttaattat aatttggcta aagaaactga aggaaaagaa cttgatatgg
    28021 atgttttaac taaaggtgta aaagcattgt tattagatga gagaaaagga aaatatcatg
    28081 tatatacagt atttgataaa gttgttgcac agattatgta tacatatgag tggagtgatt
    28141 ggagaaatgg aaatttcctt tggattcaga gtgtatatgt agataaggaa tatagaagaa
    28201 aaggtatctt taattattta tttaattata taaaaaatat atgtgataaa gatgaaaata
    28261 tagttggaat gagattatat gtagaaaaag aaaacataaa tgcaaaagca acatatgagt
    28321 ctttaaatat gtatgagtgt gattataata tgtatgaata cgaagtaata cattcgtaat
    28381 ataaatttgt aatactgtta tactgatgtt ataaagtatt gattatattg acgattatat
    28441 gaaataaact ggatattata attagaattt ttagggggta taaaaatggg cgttttaaaa
    28501 ggaatgtttt atgtattttt atttttagac ttagtgtcaa tattctgttt ctttttcaat
    28561 aaaggaaaaa tagcatctaa taaaattgtg tttaatgcaa taggagtact tacatttgta
    28621 ctttgtttta tgctttttag ttattatcct aataataatc ttattggaaa atttattgct
    28681 tctctatttt ttatatttgg agttgcagga gttatgttga aagaaaaaaa ttttttatat
    28741 gctagacttc ttttaactgt agttatagtt ttttctacat taagattgtt cgttattcaa
    28801 taaaatgtat ttgtatgaaa atttattaaa gtctacacat ttaagtgtag gcttttttga
    28861 ttttttgttt gaaaattaag gaaattttaa ggaaatttta aaatcgtctt aaatatttat
    28921 tgatatactt aaaatattaa tagcgaaagg agacttatca gtgatagaaa gtaaaaagtc
    28981 agaaaaattg ttactgtcaa ttatatacat aatatttttg gtatatattt taatgattat
    29041 aagaataatt ttatttagag atgtaccaat ttacgctatt ttcaagggaa cgtttaggaa
    29101 tgtaaattta attccatttt atacaatata tcaatttata gtagatagta atcttgactt
    29161 tatgaaagct actgtaaata ttatagaaaa tataggtata tttattccta tgggaatttt
    29221 tttacctata gtatgtaaaa atctaaataa aaaaactata attatagtaa ttatacttgt
    29281 tagcctagca tttgaattaa cacaatatat ttttgctctt ggaagtagtg atatagatga
    29341 tgttatttta aattcattag gaggcataat tggaattaat atttacataa acatgaataa
    29401 attatttccc aatgatatta acagatttaa ggctataata ggtactagtt tagttttagg
    29461 agttatagga ttaggagtta tttctaaaaa ttatcataac ttactaactt ttaaatttag
    29521 acctgataga aaaatatcaa aaatattaat tgaagaaaat agggaaataa ttaaagatat
    29581 aaataaagat acagtagata tagttgggac atttgagagc tttaaaaaag gaataataac
    29641 tattaaagca ggttctaata acaaagtaaa gagaccagag aatttaattg attctgatgg
    29701 aaatataaga atttatttaa atgaaaatac aaaattagta tcttatataa ttaccaaaga
    29761 atcaaaaatg gatatagtta aatatgagga atttgatgtg aagaatttag atttattaag
    29821 gagatatgat actattaatg tttggattga taaagaaaat cagccaaagg ataaacatgg
    29881 tattatggct agtaaattat taattggatt gtatgaataa aatattaaac aagaataaaa
    29941 gaataacaaa tataaaaaac gaaaaaacta tttctataat tatttttacg ttgtgcataa
    30001 aataagaaca ttagtgaagg agtagagata aattatggag ataataaaat atattttgta
    30061 cttttttata tattcatttt taggatggac agtagaaagt ataggatgtt ctatagcaag
    30121 caaaagaata atcaacagag gttttttaaa tggtccaata tgccctgttt atggttttgg
    30181 agcggtaatt gtgatatcac tattgggaag atttaataat gtagtaatag tatttctatt
    30241 aggaatgatt ttaactacga tactagaata ttttacagga tttattttag aaaccttatt
    30301 tcatgctaaa tggtgggatt attctgacag aaaattcaat ataaagggta gagtatgttt
    30361 aaaaaatgca atatactttg gtgtaatgtc tgttttaata ataagattta tacatccatt
    30421 tataaaatat tttgtaagta taattccata tagaatatta atttcaatgg ctataattac
    30481 aacactttgg actatacttg atttgattgt tactattata acacttaaaa aattagatat
    30541 aaagttaaac ttattagacg atataattac agaccttaat gatataaatg tgaaattgga
    30601 taaatttgat agaggagaaa tacaagcttt atttaaaaca ataaataacg acgaattaga
    30661 agttagagaa aaaataaaca aaataaatag taagttggac cgtatagagt ctaatattat
    30721 tttacaaaaa agagttataa aagcttttcc acatataaaa cataaaaaac aacaagagca
    30781 actagaacat tttaaaaaaa ttattaatga gaaaaggtaa ttatacaatt taatgaagac
    30841 gaatagaata atggtattta taagatgatt ttcagaggac tctataaaaa tagaatagag
    30901 tcctttattt tttgaaaaat aatgtttatt tgataaaaat aaaatatatt gtttctgaat
    30961 aacaaatatt ttgaaaatta taaaaacata tattgacaat ttgtgtcaaa aatactaaca
    31021 ttaagtatat aaagaatttt atatgagaat atctttataa atcgcaataa ttttaaaaca
    31081 taaatttatt taaagagggg atgatttgcc aatgagcgag ataactagtc aaatgataag
    31141 tacagaagaa aaaaaatatg ttgctaaaac tcaaaagata ccttattatc cagtagcatt
    31201 taaatcaggt gatggtgcaa tgctatatga ttatgaaggt aatgaatatg tagatttttt
    31261 agcaagtgca ggctctgcaa atgtaggtca tggtaataag gaaatctcac aagcagttaa
    31321 agaacaaatg gatgatataa cacaatatac acttgcatat ttccatagtg atcctcctgt
    31381 aaaattagct gagaagcttg tggaaatagc ccctggagat aatgataaaa aagtactata
    31441 cagtgcaact ggttctgctt gtatagatgc tgctataaaa ttagcaagag ggtatactgg
    31501 aagaacaaag ataatatcta tgtgtgaatc ttatcatgga agtacttatg gagctatatc
    31561 tatatctgct ttaagtacaa atatgagaag aaaaatgggt ccattgttac cagaagttta
    31621 tcacttccat tatcctgata aaaatagaac agctaaagaa tgtttagatg agatagaata
    31681 tgcttttgca cactatctac cagcagaaga ggtagctgca atatttatag agccaattgc
    31741 aggagatgca ggaataatag tgcctccagt agagtgggta caaggtttaa gtaaaatatg
    31801 taaagaaaat ggaatattac ttgtaagtga tgaaatacaa caaggtatgg gaagaacagg
    31861 taagtggttt ggtatagaaa attttggtgt tgaagcagac cttatagttc ttggaaaatc
    31921 tgttggaggt ggattacctc taggagcagt tgttggaaga acagaaataa tgcaaagtct
    31981 tgatgcacca gcacatttat ttactttagc tggaaacaca acagtatgtg tggctgcttt
    32041 aaaatctata gagataattg aaaaagaaaa cttacttcaa aagagtatag aaatgggaga
    32101 ttatattaaa gcaggatttg aaaaactaaa agaaaaatac gatataattg gagaaataag
    32161 aggcatagga ttatctatag gagttgatat agttaaagga aaaggttcta atgaaaaaca
    32221 tccagatgct acagctaaga tatgttatag atgtatacaa actggattaa taatgatatt
    32281 cttaggacaa tctactttaa gagtgcaacc acctctagta ataactaagg agcaagtaga
    32341 taaagcaatg aacatcatag attctgcaat agatgattat ttaaatggta gaattggtga
    32401 tgaagtatat gaagtaactc aaggttggta aaataaatat taaatgaaaa taggagttat
    32461 ctcaatttta gaaaattatt tctgaaatga gataactctt ttaagttacc cacaaataag
    32521 aaaattgttt gattcattaa agactatatt tcggatgtcg tttttgtgag tatcagagac
    32581 agtattacga gaataattac ctttattcgt actatctgtt aatttagtta taattaagat
    32641 agctaaaaga ataagaatta ctgtgtataa agcaataaca tatggttttc ttttatattt
    32701 gtatttgtta ttgaaaaaag aatggccata attattttta tttactttag atgtatttgt
    32761 attctttttc ttgttacctt tctttttatc atcctttttt ctatttttag ggtaaggaat
    32821 gactttgtgt gtattatcaa gtttgatatt tttatttttt tgaatattgt tttccaggct
    32881 agcctttttt tctccaaatt gaatagtttt attggtattg ttgttatctt tcaatgttaa
    32941 tctccctccc ttaaactttc cctttagata atattactac taacctatgg aatatacaat
    33001 aaataatata taagtaataa aattttatag gtataaatct ctttctccac gctctaaggc
    33061 agtcatattg ttagatacta tgtttcttat atcttctctt tctatcttac ctatttcttc
    33121 tgcgataagt tttttaccca taattttaag ttcttcatct ccataatcga ttaaaaattc
    33181 atttaatgta gtaagagcat ttggtgtaca tacattatgg atttgtcgac ttttagctaa
    33241 gctcatgaat ctatcgccag ttctaccttt acgataacaa gctgtacaat aactaggtat
    33301 atatccatca gtaatcagtt ctttaagcac ctcaacaggg cttctatggt ctccaacttc
    33361 gaattgttct gtattgtcac catcttcata tgctttatat cctccaacac ctgttagaga
    33421 acctgcacta atttgtgata caccatattt tagtaactca tttctcattt cagcagtttc
    33481 tctagtggac attatgattc cagtaaaagg aacagctaat ctagttatag ctactatttt
    33541 tttgaacata tcgtcagaaa ctaagtgagg aaaatcttct aagctcatac cttcagcttt
    33601 tttcaatcta gggaaagata tagtatggaa acctacacca aatttttcct ctaagtgttc
    33661 gttgtgcatc ataagtccta gaacttcaaa tttagggtca gataaaccaa ataaaactcc
    33721 tgcaccaaca tcatcaacac cagcttccat agctctatca aaagctgtta aatggtaata
    33781 atagtcattt tttatagatt gaccatgcat ttttataaat gttggtttgt gataagtttc
    33841 ttggaataat atataagttc ctattccttt ttcttttagt aatttatact catctacact
    33901 tgtagctgct atgttaacgt ttacccttct tatatttccg ttttcattat atgttgaata
    33961 aattgcatct aagcaatcta agatgtaatt tatatcacaa tttttagggt cttcaccagc
    34021 ttctagagca agtcttttat gacccatttt ttctaatatt ttaacctctt cttttatctc
    34081 ttccatggta agtttttttc ttttaaattt gttgcattta ctaaaaccgc aataaacaca
    34141 ttcatttaca cagtagtttg atacataaag aggggcaaat aaaaccactc tattaccata
    34201 tatttcattt tttatttgcc cagctatact aaataatcta tctagttgtt ttttatcttc
    34261 cacttcaaga agtgtagcta tatctttata actaagtttt tcccttctat cagccttatc
    34321 aagtaccttt tcaatatcat cagaagttga attttttgca tcttctaata aagaattaat
    34381 aagttcatgg tttatgaaca tttacaaacg cctccattca atattatcac cgcgagaata
    34441 gtcaacttca agtcctaatg acttgatgtt ttcttctaaa ctttggtgat attcacaagc
    34501 ttcttgacca gtaaaggctt tgttatcgta aagagaatat tgttttctaa attcttgagg
    34561 agaaaggttt ggcataatta cattgcaacc agctaaaaga cctgcatttc taccactagg
    34621 gtttatagat gccaaggctg ttgtagcggg taataaaact tttggaagta gaagtcttgt
    34681 aattgaaagc ataagtaatg tcttctctaa atctccatgt ttataatcct taaaaattgt
    34741 atcatggtgt ggaatgaaag gtcctattcc aaccatatga ggatttaact cttttaggta
    34801 taataaatca cgaacaaggt cttcgttgtt ctgaaatggt gattcaacca taaatccagc
    34861 acctacttga taaccaattt ctttaaggtt ttttaggcat tcttttctag ttctaagctc
    34921 aatgtttggc ggatgtaatt ttttataatg actgtctgta gcagtttcat gtcttaaaag
    34981 atatctatct gcaccacata aaaagtattt tttatacgaa tcataactct tttctcctag
    35041 tgatagagtt atggcacaat cctcatattt attttttata cttgaaacaa tttcacatat
    35101 tttatcatca gtaaaatatg catcttcacc accttgcaaa acgaatgttc tgtatcctat
    35161 tttataacct atatcacaac attcaagtat ttcatcaagt gaaagcctgt atcttatgat
    35221 atttttatta gaagattgta ttccacaata gtagcaatta tttttacaat agtttgtaag
    35281 ctctataagt cctctcaagt agactctatt tccataatgt ttatttctca tgtcgctagc
    35341 ttgtttataa agatagtttc ttaaattttg ttcgaagtta tattcctcat tgtcgatatt
    35401 ttctattaaa tatagtagtt catcaaaact taatgaatta atgctgtaaa gtttatctat
    35461 aaagtattta atcttatttt tagtcatatt caaatatgta attattaagt atagttaaat
    35521 ttttaataat tgaaaagttc aagtgatctt tccaaaatac cttttacata tgctattaag
    35581 acaccatagt ttacaatagg tacattgaaa gattttgcct tttctattct agataacatt
    35641 ccagctctat tcatcataca agctccacag tgaactacaa gggcatattt atttatatct
    35701 tcagtgaagg atactccaga actaaattca aaagtaatgt ttttgccagt tttctttcta
    35761 atcatattag gaatttttac tgttccaata tcatcagttt gtctatgatg ggtacatcct
    35821 tcggccatca agattttatc accatctttt aaattttcta aagcataagc tccattaatc
    35881 aattctttaa ggtctccctt ttgtctagca aacaatatag aaaaagatgt aagaggaata
    35941 tcttttggtg tatctttatc tacttgtgga aatacttgag agtcagtaat aacaagtttt
    36001 ggttttttgc ctaaattaga tagagtttct tttaaactat cttcttttgt aactatagaa
    36061 attgcaccat tatccaaaat atctcttata acttgctgtt gaggaagtat aagtctacct
    36121 tttggagctg ctttatctat tggaacaact aaaacaacta aatcatttgg ttcaattaaa
    36181 tctgatacca atttgaactc agtgctatcc ttaggcaaaa cttttattat ttcatttttt
    36241 aaattttcaa ttccaatttt atctgttgat gagacagaaa caactggaca tttaacttta
    36301 tttttagtta agtttaaaat ttctgattga ttcttaatag tatcaatttt gttaagaatt
    36361 agaatatgag ggatattctt atcattaaat ttttcaatta gtgacaaatc ttcttgtgat
    36421 ataccaattt ggcaatccac tactagtaaa gctatatctg tcttttctaa aacatctagt
    36481 gatttaccta ttctaagttc accaagttca ccaacatcat caagaccagc agtatctata
    36541 agaacacaag gtcctatagg aaggatttcc attggtctaa atactgggtc tgtagtagtt
    36601 ccagcaatat ctgagactat tgcagcactt tgatttgtta tagcatttat tatgctagat
    36661 ttacctgcat ttcttttacc aaagagacct atatgtactc ttaccgattg tggagtagaa
    36721 tttagactca tttgtactca ccaccttaaa cttctttttt tgatatacta gtttttacag
    36781 atacatgagg tatgttgcct aatttaccag tcaaactatt aatagtatcc atttcgccaa
    36841 caactgctat acatacgatt gagacacctt cttcttcgca aggaatgccc attcttcctt
    36901 taataatacc tttaaaacct gatacaacct cattgaattt aaattgacat tcttttggct
    36961 cttccaaaat agcacttata actgcaacct ttttcataaa tatcctccta actcagaaaa
    37021 tatgtcttaa acaaatccaa aatcaaaaaa cttttctttg taaagaaaag tttctacaaa
    37081 agaaaagtta ttaattacac aagtataatg tgctatatta aactatttcc ttacagatta
    37141 gataactctt ttctggtagg gttagcttgt aaaaatttaa tttaacaaca agtaactgaa
    37201 gaaaattttt atacaattta tataaattat aataaaaatt aactaaagaa aattgaagtt
    37261 acttatataa tagtagtaaa ttgaaattaa gtctatagaa aaaccaattt ttgtataaaa
    37321 ataaaaatta aagttaatta tttgttaaga attgactttg gtaaaatata taattaatta
    37381 ttctttaagc atataattta taagtaattt tagtgtattt tcaatagctt ctatatgtgt
    37441 tctttcataa tggtgactat tgtttgttcc aggaccaaca catgctattt gaacatcttc
    37501 tccccaacga atagcttctg aagcatctga accatagaaa gtaaatacat cgacagcgta
    37561 gtctaaatta ttgtcttctg caacatcgac aagcttgttt cttaaattaa aatcatataa
    37621 tgataaatta tcttttgcaa ctatagttac accatgttca ctagatgttt gacttggtcc
    37681 agtaggtgct atatctattg ctacaaattc ttttgttttt tcaggtaaac atttagaaac
    37741 accatgtcca atttcttcat aattacttat ataaaagtta gtagtatgct taggtgttaa
    37801 attgttttct ttaaaatatc tacatatttc aagaaccatt gctacagctg atttattatc
    37861 tatatatcta gattttataa aaccagattc tgtagcctca aatctatggt ctaggcatac
    37921 aaaatcccca acacttattc ctaaatctaa tacatcttgc tttgtaaata ctttttcatc
    37981 aagtctaata atcattgttt cttcatttct ttcagtggca gcttttgttt gaccatatat
    38041 atgagtagaa gcatacttaa atacaacact tcctctgatt tttttacctt ttctagttat
    38101 aacagtacag ttttctccct ctatagctgc ccaacatcca ccaccaactt tatggtattt
    38161 aagagtacca tcagatgata tttcttttac tatagctcca agtgtatcca tatgtgcaga
    38221 tattgttatt tgatttgaat catcttcacc aggaagagta gctataagtg cacctttttt
    38281 tgtaagaata gtgtcaagac ctaaattttc aaaatctttt ttgatttcta aaactgcatt
    38341 ttcagtatat ccagctgggc ttggaatgtc caaatatttt ttcattaaat ttatagtatt
    38401 agttaaattt aaattcatat tgtttcctcc taaataaata tatttataca aattataaca
    38461 taaatacaaa tgttctgaaa actaaaatta aaagaataga atctaaacat atttaaaaaa
    38521 aaagtatata aaataaattt gatttatatt atatagattt aaagtaaaaa tagttttatt
    38581 taataattaa taaaaataaa tacaaaacaa aataaataaa taataaaata tttagtttaa
    38641 ttatctttac aaataaaaat tttagtaata aaataattgt tgaaaaagat tttaaattca
    38701 gattattcat ttctaaagta attaatgtgc aaatctttat taatatatgt taatagttag
    38761 gtatatatgt atttaattag tatgatatag ataaaagtat ttattttaat tgtctattat
    38821 ctgaaaaagt ctttacttag aaatcataaa aatcaaatta attaggaaaa gaaagggtgt
    38881 gtataatgtg attgagactg gatttgtata ttgtagtttc ttggttgtat tcgtaggtgt
    38941 aatttttttt atggttgata aattgaaatg gaaggtattt gatgttatta atccaatgct
    39001 tttaatatac ttaggttcag ctatacttgg atcatttggt ttatttgcac agaatgaaga
    39061 tgttggaacg tatcaaaaca taataacagt gaacttcctt ccattaatgt tagtgttttt
    39121 gttaattcaa tgtgatttaa gaaaaatatt aaagatgggg cctaaaatgt tattatcatt
    39181 tttctgtgct acatttacat ttatgcttgg atttgttata gcattcataa tttttaaaaa
    39241 ttcaatgggt gcagattcat ggaaaattct tggggcagca tctggttcat ggataggtgg
    39301 ctcatcaaat atgattgcag cagctaatgc tctaggagtt gcagaagaag gacttagtta
    39361 tgcaatactt atgggttcta taggatatac agtatggatg tctgtttgtc taatgtctgt
    39421 gaaatttgga cctaaattta acaaatggac aaagtgcgat acaagtttta tagatgaggt
    39481 tacatcaaaa cttgaaaaag aaaataaaga taatacggca cctacgtttg tagaacttat
    39541 gattttactt tctgttgggt ttggagttgc gtcttttgca caaattgtat ccaagatact
    39601 tccaacttca ggtatactta atgaaactat gtgggtagta cttgttgcat ctacagtatc
    39661 aatattattg ggtatgacaa aaatatcaaa gcttaaaggg agtacactgg taggaaatgt
    39721 gtttatgtat ttactccttg cagctacagg tagtaaagca aatttctttg gattgtcaga
    39781 agcacctgtt tacataatgt ttggattggt agtagtcctt gtacatgcta tttcatttat
    39841 agggcttgct aaactattta aacttgattt atttacttgt gaagtaggaa gtatagctaa
    39901 tataggagga gtaactacag ctccaatgat tgctggggtt cacaatcctg tattaatacc
    39961 agtaggtgta cttatggggc ttctaggaaa tattataggg acttattgtg ctcttatggt
    40021 aactcaaata ttacatatgt tagcttaata aaaatatggt ataaaattaa taatttaaat
    40081 aagaaaagtc atttcaattt aagcagaagc ttttactgaa atggcttttt tgtttgacaa
    40141 gataatctat ttcaagaaga tgttttgaca tatttagtgt ataatattgt aaaatttact
    40201 aaaaacgaga tatatttaat ttttatattg aatcgaacgt ctgtatgatg tataataaat
    40261 atacagaacg aatgtttgca gaacgggtgt tttttgaatt tattttaata atttatgaat
    40321 atatatcaga atgcataaat atatttaaat ataaagatta aaaagaattt aaaggagtgt
    40381 tgataactta tgataattcc atcaagaaga atacaagata taacattaac aaatttaaaa
    40441 aatggtgaag taactttaat tgaattggat gaaatataca agaagatggg atttttattt
    40501 gttgttagtg aaggcaaatt gaaaaagata aaaaaggaga atcatcatta gaaatgaatg
    40561 aaataataaa tattataata gtttataaaa cctaacttat gtagaatata aatacttaag
    40621 ttaggttttt ttgtgataaa gtttataagt actcaatttt ataagataaa taatggtctt
    40681 aagtgaaaag taaataagtt taaattttag taagtattat attgcataag aggtgatatt
    40741 attatgaaaa tagtaaccta caatattcat aaaggtatgg attcaaataa tagattaact
    40801 ctaactaaaa tggggttata tttaaaacaa ttggattgtg atgtaatttg tttgcaagaa
    40861 gtattatatc ctcaattttt agctttaaaa gctgttttaa atatggatgg tgtctttgcg
    40921 acaaatgtaa aaaaagtaaa tatgatatat ggtatttgta catttacaac atctaaaatg
    40981 ttaaacagta atcatttttt cttaactagc aaaaaagaac aacggggagc tctttgtata
    41041 actatagatg catatggaag aattataaat gtaataaata ctcacttggg acttgatagg
    41101 caggagagag caaaacaatt agacgaaata atagactata ggaacagatt agtggggata
    41161 gttattttat gtggtgattt taatgagaaa aatgtctttt taagtatgtt taatgatatg
    41221 gctatttcac taaacaagtc ttacttacca acatttgaaa aatcaaactc tagaatagat
    41281 tacatttttg ttaataaaaa tactgaacta aaaggataca cagtagaaaa aatttacctg
    41341 tcagaccatt atcctgtaat aggttacatt taaatttcaa tataaatgaa attagttgtt
    41401 ataaaataaa caattttttg ttaagaaata gtaaaagaaa tataataaaa aatatcaaaa
    41461 ataaaactaa ttataagaca taaatttaca ataaagttac atttgattaa attccttgtt
    41521 taacaaaagc tattcaaata taatctaagg tagttttgaa atgggaactc tattatgcaa
    41581 atttaagcta gtgttaaaat gaggtgaagt tatgggcaga agaacaacaa gagtttcaag
    41641 attaggtaaa gaaaaaaaac gaagtgtttt aattgtattg gcagctttag ttctaataat
    41701 gggtggattt acttattttt ttaacagtaa atttctgtac aatgggaaaa tcgctaaaaa
    41761 tgtatatata gaaggagtaa atgtatctga tatgactaaa gcagaggcat taaaaggtat
    41821 aacagataag tatactccag aagacttaaa tcttgcttat gatgggaaaa aatatacaat
    41881 atcaccaaaa gatattgatt taaaatatga tacagaagat gttgtaaaag atgcttatga
    41941 aagtacaaaa aaagggtcct attttcaaaa cttaaaaaaa tatattgata taagagtgaa
    42001 taaggcaaat atgaagataa aagctgaata tgatgaggca aaacttagtt ccaaagtgtc
    42061 ttctatagca gatagtataa atgttaagat gaaaaatgct tctattagtg ttggaagtgg
    42121 tggactaagt tatacagact ctgttgtagg tagagaattt gatttggcag caaataaaga
    42181 gtctatatat aatatgataa aaaataaaga gcataaaact ttagaactta aagtaaatct
    42241 tcaaaaacca gatataacaa ctgaacaagt aaaaactgta aattctgtta taggtcaata
    42301 ttcaactact tattcacaag ctgtagaggg taggtcatat aatgtaggat tatcagcaag
    42361 aaaaactagt gatgtattat taatgccagg tgaagaattt tcatacaata aacttacagg
    42421 acctagtaat aaagcaaatg gttacaaaga tgcacctgtt atagtttatg gtaagctaga
    42481 acaatcagca ggaggaggtg tttgtcaaac atcttcaaca gtttataatg ctgctcttct
    42541 ttcgggtatg gagataactc aagttacaaa tcattcatct gcatctactt atgtgcctaa
    42601 agggagagat gctactgtga gcgatggagg attaaactta aagtttaaaa atccatataa
    42661 gcatcctgta tatattaaaa attatgcagg tggaggaagt gtatcatcag taatctatgg
    42721 taattctggt gacaaaccaa atatatctat agaggtaaaa caaactggtc agaataaata
    42781 ttctacatat cgaatattta aagattcaag tggaaaggtc ataaaaaaag aacatatatc
    42841 aaatagttct tataaagaat taaaaaaata gataattttt tagagaaata tttgtaatat
    42901 aaaagggagt gtctcaaaat gaacttttta gtttagagac actcttttta tgtgaaatca
    42961 aatatatttt catcatttca acaatacaaa agaagcgtat ctctattttg agacagcctt
    43021 ttttgtaaaa attaacacta ttagttcttg ttttaatatt acaatcatta atatatagaa
    43081 aatattccta tatattggta taattgtaaa tagatttagt tatataaaat gtatgaggag
    43141 gtgacatggt tgaattttat aggcaataga tatgaggtag taaattctga tgacgtttta
    43201 gaaattaaca aaatctataa agctagagat gttttttaca ggaaaaatgt gttgataaaa
    43261 gttataaagc acaataatta tatctgtgaa gattttgttt caaatttaat tgatgaaagt
    43321 actgctttag atgagataaa ctctccttat atactaaaaa taatagatgt tgggattcac
    43381 tgtacagaag aaacaacatt atattatgtt gtaagtgaag actttaatgg tatcggacta
    43441 gatgaattaa ttctaggtaa ttatcttcat ttagaagcaa ttgtaaacat aatgatacaa
    43501 gttttaaaag ctttagaaat gatacatagg aatcattcat atcatggtag tttaaaatcg
    43561 agtagtataa tagtagatac agaatacaat ataaaaattt gtgattttgg aattacaaaa
    43621 gcaaataatg gggttaatac aagaagctat ggaaacagga gatatttatg cccacatcaa
    43681 ctatgtataa attatactga taaagaaagt gatttttttg caacaggtct tattctattt
    43741 gaatctatat ttaaaaaatt gccttttgga gaatcaaatt cagaagaaaa aatgctacaa
    43801 tctattgata agggattaga ttggaatagt ataaaagcaa ttaatggaaa tactgaactt
    43861 ataaatgtta taaaaaggct tcttggaaga aataataagt ataccagagc caatgatatt
    43921 attattgatt taagtaaagt aatgtatgaa aaagcatata tagaagttga agatgagaaa
    43981 gaagaagagc agaaacaaga caaagttata caatttaaaa aagaatataa aagtaaaatg
    44041 agaaaaaaat tacataaaaa acttgttgtt gccggtctag ctatagtcat gatttcaatg
    44101 attattatta gttccataat ataaaaattg tatattaagt attttaaaat caatgtctat
    44161 aaaggatata catagaaatt ttagtgtagt cttaaattat gaaaggaagt ggttattatg
    44221 ttaacaaaaa ataatgaggt attaaacgtc taggagtatt ttaacaaata gccacctgct
    44281 tttacagttt agaataaaaa agctgtggct aaaggtcaca gctttttgct actttttaaa
    44341 ggcaggagaa tattaaaaag gagcaaatta tgagcaatat aaaaataata gcaagtaata
    44401 aatgttggat tgaagatata gcaaggaaac aacttgaaga tatttcaaag ttaaatggaa
    44461 ttttaagagt agtaggatta cctgacttac atgcaggtaa aatacctgta ggtttagcag
    44521 ttgagactaa aaatattatt tatccacata taattggaaa tgatatagga tgcggaatga
    44581 ctttatttaa aactggggtt ctaaaaaaga aatttaaaaa agacaaatgg attaagtcac
    44641 ttagtaagat taaagatttg tctgatatag aaataaaaaa cacatataaa gaagaatgtc
    44701 caattttaaa tttaggaact atagggagtg gaaatcattt tgtagaaatt caatgtataa
    44761 gtgaaattta taataaagaa caatttgaac aattaaaatt ttcatctgat gatattatga
    44821 tgttagttca ctgtgggtca agaaattatg gagaagatat tttaaaaaaa ttttatgata
    44881 aagatggact tgaagttgaa agtgagaaag ctatagatta tattaaaaaa catgataatg
    44941 ctttaatgtg ggcagagcgt aatcgtgaag ctatcagtaa aaaaattatg cagtcaatag
    45001 gtacatctgg agatgttgaa acaatattct ctataaatca taattttata gagaaaaggg
    45061 aagataaatt tatacataga aaaggtgctg tttcaagtga aagaggagct gtgattatac
    45121 caggttcaag aggcagtcta tcatatatag ttatgcctac tgaaaataca gagatatctt
    45181 tatattctct atcacatgga gcaggtagaa aatggtctcg ttcagtttgt aaatctcgcc
    45241 ttaaaagtaa gtatagtaaa gatactataa aacaaactaa atttaaaagt cagattatat
    45301 gtaatgatgt aaatttatta tttcaagaag ctccagaggc atataagaat atagagcaga
    45361 ttattgaaag tttgatagaa tatgaactta ttcaagtagt ggcaactatg aagccattga
    45421 ttacctataa aggataattt ttaaagttaa aaaagattaa aattatatta taaatagcta
    45481 attttatgga acatttaaaa gtgttttatt attagctatt tttttatttt gtagagacga
    45541 taatttatag agctaaattc tttgatatat aatgattaca aagttagact gtattggaaa
    45601 atgcacatac atgaattgat gacaatataa gtgattctaa aatataaatg aaggtataag
    45661 cttattttca ctataaaaat tttcactgta caaaaacatt aatgacatta tttttattga
    45721 cataaatata taatttatgg aataatatta gatgcactga tataagtgtt taaataagaa
    45781 tagaaaagga gaagtgtttt atgaaaaaaa atactaacat taatgagtcc ggagttaaac
    45841 ttcttaataa ataaggagtt tgatatataa taactcctta tttattaagt tgttcgcaaa
    45901 ataactatta tcaaagtaaa tgatagggtg atttaaaaga cgataactta taaataaagg
    45961 agaaaaaata atgaatagta atacatttga aagattacaa ctaaatgaag ttaaagaatt
    46021 aataaaaata cattgtgtaa gttcactagg aaaaaattta atagataaat taactcctag
    46081 tgggaatatt ggagtagtaa gaaggaaatt agcagaaaat aaagaagcta gaaagataat
    46141 tgaaaatagt aatcacatac cacttgaagg attgtttaat gcaggttcta caatagataa
    46201 aattgaaaaa ggaatgataa tagaacctgt tgaacttgta aatattgaag attttttaag
    46261 aggttgtagg aagatgaaag cttttatgtt agaaaaagaa ttttattcac ctacattaag
    46321 ttcttatgcc ttaaatataa cagaatgtaa aagtatagaa gatgagataa attactgtat
    46381 aaaatctaat aaagttgatt ctaatgctag taaagaatta aaaaagataa gacgaaatat
    46441 agaaattaca gaaggaaaga taaaagatag attaaataaa tttataacat caactgtaaa
    46501 taaaaagtat atacaagagt ttataataag taaaagaaat gatcgatatg taataccaat
    46561 taaatcttct tataaaaatg aagttaatgg tactatatta gatacatcat caaaaggaaa
    46621 tactgtattt attgaaccta ttagtgtttc aaatttaagt acagagttaa ctatgctaaa
    46681 agctgatgaa actattgaag aatacaaaat attatcttat ttaacagaac ttatatttga
    46741 gaagataagt cagataaaat taaatataga gatactttca gaatacgata tggtatttgc
    46801 aaaagctaag tatagtcaaa aaataaaagg aattactcca aaaataaata ataatggcta
    46861 tataaaaata attaaaggta aacatccact tctaacagga gatgcagtac ctttagattt
    46921 tgaaataggc aaaaattata gaagtcttat aataacaggt cctaatgcag gaggaaaaac
    46981 tgtaaccctt aagactgttg gtttactaac tttaatggtt caatgtggat ttgatatttc
    47041 tgcaaaagaa ggtagtgaat ttagtgtatt tgaaaaagtt tttgtagata taggggataa
    47101 tcaaagtatt gaaaatgcct taagtacttt ttcatcacat ataaaaaata ttgcagagat
    47161 tatgagttta tcaaataatt ctactcttgt tctgtttgat gaaataggaa gtggaactga
    47221 acctaatgaa ggagctggtt tagcaatatc attattagaa gagttttaca aaatgggatg
    47281 tataactata gcatcaactc attatggaga gataaaaaag tttgctacat tgcatccaga
    47341 atttgaaaat gctggtatga tgtttgataa agaaacgtta gaaccattgt ataagttaac
    47401 tattggaaaa tctgaagata gtaatgctct ttttatttct aaaaaaatgg gaataaaaaa
    47461 tagagtttta gatagagcta aagaatatgt aattgataga aactacaatt tagatttagt
    47521 taaaagaagt aagctacaat ctaatattga agataaaaat agttctgaag tcattttaaa
    47581 ctatacagat tataatgtag gggataaggt aaaattacta gatgaagatg attttggaat
    47641 tgtatataaa cctatggaca agtttaataa tgtagaagta ttgtttaatg ataattttat
    47701 ttcagtaaat ataaaaagat tacaacttag cataaaagca tcagaattgt atccagaaga
    47761 gtatgattta gatgtattat ttactagttt taaagaaaga aaattagaaa aagatattca
    47821 aagaggttca aaaaaagctc ttaaaaagat tcagaaagaa attagagaga atagaaaata
    47881 aatataaaaa gcacaaaaga aagcaatcta aagagcaaag tttatcttta gattgctttc
    47941 ttattaacat atcttcataa atccaatgac taacaagatt aaaccactta accaagataa
    48001 gtttaaattt acgtttttaa caaacatatt tcctagtaaa caaccaagta atactgcaat
    48061 tatatttgat attaaagaaa atagaataac ttgtatataa ttcacaccta caaggccact
    48121 accaaaaccg atagctaatc catctaaact taaagcaagt gcaagtgtaa atgcttcagc
    48181 agatttaagc actttagatt tacttgtatc taagacatca ggttcgatac ttacattaaa
    48241 atttaattta aggtctaaca tattaaaatt ataattcttt gagtgtatag attttttctt
    48301 aaaataagat ttaaaaaaac tttcaattag tctagcactt cctaataaaa ataaaataaa
    48361 gaaacatatt aacattgtta tattttgagg taaaaagtct ctaactattg tacctgcaaa
    48421 aagcgatatt gctaaaatag ctgaacaaac tacgctgata attatatttg aatataaggg
    48481 aactttaact ttatttacgc catatccaaa gcttgtcaca aaggcatcta tacaaagaga
    48541 agtaactaat aaaattgatt caatcacagt agattaacat cctttctctt aaattttgta
    48601 cttatattag ttatagtatt gtaaaaatgg ataaattgtt acagataatc caataaattg
    48661 ttgataaaat tccaacatca tacaacacct aaataacaaa agaatcatat catataataa
    48721 tataaaacca atcataataa agcgggtgaa aataatggaa caaaataata aggttgggaa
    48781 tttcggtgat ttgttgaaga ttttattaga tgaaaaagaa ttatcaatgg gagaactaag
    48841 taaaaaaagt ggaattgata aatctactat atctcgtata gctaataata aacaaaagcc
    48901 aaatataaat catttagaaa agatggcaat acatttaaat attaacctag aagaactgtt
    48961 gaaagcttca ggatatgaat ttagaaacag caataatcaa atatttaatg cagatagtga
    49021 ttttagtaac tttgatgata ttcttggatt tgcaaattta atcaatgata agaactttaa
    49081 tggaaatatt gaaaaagagt tgagtaagtg taagttatat gtccaaacag atgaaggtaa
    49141 aaaattactt tttgataatt ttaataaaaa aatagattct attgaaaaac aaggtcaatt
    49201 tacagacaga ttaagacaaa tgtatgctga tttttgtaca gatggactta caataaagaa
    49261 atatttattg attggaagta tgctacttta ctttgttata tcaacagatg tgattccaga
    49321 cttcgtgttc ccaataggat ttatggatga tttagtagca ttaaatatag ttacaaaatt
    49381 acttaaaaat gataagtaag ttttagaatc atatttaata tataaataaa tcaaagtata
    49441 taaaatttat tatttt
//
LOCUS       DAFAZV010000028        45296 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFAZV010000028 DAFAZV010000000
VERSION     DAFAZV010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45296
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.028"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..2418
                     /locus_tag="KOU88_002313"
     CDS             <1..2418
                     /locus_tag="KOU88_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing protein"
                     /protein_id="HBK3212187.1"
                     /translation="GETCNINFLSDGFIELFGYTREEIKTLFNNDFYSLIHKDDVERI
                     KKEIFKQLYKNKTVELEYRIITKNGNTVWVLDKGELITEPDGKEYFCCVTVDITRTKQ
                     LEQEMEQKNLELEMISENVLGGIIITEFNDDFTIKYANSGYLSMIGYTREQLENELKY
                     KACNLVFYEDRKKALESIQHQLNTKGIAVYQHRIRRRDGNIIWVSIKGRLIVDDDGIE
                     KGIWILNDITDLKNAEQKLKINEERFRIALKQTSNTIFEYDIKTKSLLNTSKELDKYN
                     IYKITKNVPYSLVESGVIHKDFSDDFINMYENVINGAKKASCVVKMKLPDENYIWNKV
                     TLTTIFDEDGNPVRAIGIQEDISKQKEAEIRYNQEGKYHSAILSEAMITYEINVSKDT
                     FIKGNESWQKPFGIKPDNNYSQMVKTIANSIVHKDNKETFLNTFLCENLLDAYKNNVT
                     EIKLEYRRMNQENKMIWVICTMHLIKDSITNDIKALAYVKDIDKQKNEEIRLKLKAER
                     DTLTGLYNKGTTEKLINDFLNSEEASLGMHAFLIVDIDNFKSVNDNLGHVFGDKVLFE
                     VSKNLKPIFRKDDIVGRIGGDEFIVFLKNIQSFENIKKKAEKICDIFRNSYTENKKTY
                     KISGTVGISFVPEHGTVFEELYKKADIALYYAKSKGKDKYALYNDCIYQNELENNISD
                     NNIKLADKCEKSKPVLKEILDSIDNYIYIVNPNTYELLFVNNKVSRLDLEIKLGETCY
                     KSLLKSDRPCNNCPLNGLEENKHSKFKIETNTFGKNISIASWINCIDGEYNCLIECID
                     SSLYKNK"
     gene            2436..3182
                     /locus_tag="KOU88_002314"
     CDS             2436..3182
                     /locus_tag="KOU88_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBK3212188.1"
                     /translation="MLNSITLILGIIFTIYYFYLKIVFGGISFSEIFLVVGIVLIIYQ
                     IFKKKIKEKKVFYRVLKIIISIFLIVFVVTESLIIFYPKNSLESKSDYLLILGASVKK
                     TTPSTTLKGRLDTALKYLKINDNCYVVVSGGKGSGEKITEAKAMKDYLIKNGIDKNRI
                     IEEDKSTNTYENFKYSKLKIEEHSQGKLSDLKVKIVTTDFHVLRSKILAYRNGYKNTS
                     FYASKSKLSFVPTYYTREFFALWKTIIFDR"
     gene            complement(3131..3439)
                     /locus_tag="KOU88_002315"
     CDS             complement(3131..3439)
                     /locus_tag="KOU88_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBK3212189.1"
                     /translation="MNFFKENSTFYFATVEDNKPRVRPFGFIMDYEGKLYFGIVKYKT
                     SYKQLLVNPNVEISTTSKVGKWIRIKGIEKTRYEFISSLFIYYLSKMIVFHNAKNSLV
                     "
     gene            4242..8384
                     /locus_tag="KOU88_002316"
     CDS             4242..8384
                     /locus_tag="KOU88_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF11 domain-containing protein"
                     /protein_id="HBK3212190.1"
                     /translation="MATVSGQIVFDRNRSATIDSGDSGIANIPVVLQDIATGVRLVVL
                     TDASGNYVFTNVPNGNYRIVEAFGTTGGVPTPGNFATAIVGPVPIAEMPPISSVTNPP
                     IGSTNLDGTTPNTLLITVAGSDITNQNILNGPVIYTPIENILDSCVSVSNINLITDAD
                     NGTFGFFPPGTPSNTGPEIEPYPNVTPDFTYVVPDPTKFTPLDGEYTVQNIMTNAMSN
                     VIGAWWRIADHTTGNETGRMMVVNGFNPGAVFFKSTVQVTPNTNYLFSTWILNLFKVT
                     GYPPPQLGVRIFDQNNNILYQATLGAQIPVNTNAPEWKEVGTVINSQNNNQLTVEFFS
                     EGESAIGNDYAIDDVSLREIAVPTFTPIKTSNTETANVGDIITYTVTLDNTCDSPLTN
                     VFFRDLIPNGLEFIPGTVTVDGVSVPGVDPNTGFPLPDIGGGTGVEVTFDAVVESIPN
                     PNPTNNIANIDYSYTPVEGGIPNDFSVDSNPVPVEVVSADIEVTKLSEPTIVNPGEEL
                     IYTIKVVNNGPFPSENVVLTDDLPASIINPEYSLDGGVTFQPWNGSLNIGTLEVGETK
                     VIIIRGIVNPSTVGIITNTAVVSSTTADPNLNNNTSTIETEVNLLADILVMKTAEPNS
                     AVPGTLLRYTIQVENLGPANAENVILNDDIPASIINPEYSLDGGASFQPWNGSLNIGT
                     LNSGISLTVLIQGTVSLNSSEYIVNTATVSSTTPDPDLSNNISTIITPVNPQAGISII
                     KVADEDVAVPGEEFVYTIEIFNEGPSNATNVVLTDDIQDVILNPEYSLDGGATFQPWT
                     GSLNIGTVAPGQLIRIIIKGLVSSTATGDITNTAEVSADVPEPVTDSSTVTTPIVPSA
                     DIEVIKTSNMDTAVPGETFSYTITVTNLGPSAAQSIVLTDDIPDVILNPEYSLDGGVT
                     FQPWNGNLSIGTLDAGEIRSIIIRGTVSQTAVGTIINTATISSTTPDPNPDNNTSTDE
                     TDISPLADISVIKGNEPVAIPGGRFIYGIEIANAGPSFAENVTLTDNIPASILNPEYS
                     IDNGVTFQPWNGSLNIGTLDAGEIRNIIIRGTVSQTAIGTIINTATVSSTTPDPNLNN
                     NISTSEAEVSSSADISVVKRSNQTVVVPGDVLDYTIEVRNAGPSTAQNVTLTDNIPAS
                     ILSPEYSIDNGVIFQPWNGSLSIGTLDAGEIRNIIIRGIVSQTAIGTIINTATVSSTT
                     PDPNPDNNTSTSEIDISSSADISVIKLANKTEACVGEQIDFVIVVSNAGPENAQNVTL
                     IDNVSDKLKKAVFSLDRGVSFQPWTGSLNIGTLPAGTLRVILLRGIIKSTCLDRLTNI
                     AEVTSTTPDSNLNNNISRVQVEIKQCCCNDCCCNNCSNCCCNDCGCKNCCCNCCKNDF
                     WC"
     gene            8841..9188
                     /locus_tag="KOU88_002317"
     CDS             8841..9188
                     /locus_tag="KOU88_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBK3212191.1"
                     /translation="MHENKKNLLDGSLAQYNDTAVPKIPVFAGNDITSEVYYFKPNQV
                     LNAHRHPNGEQIFVFLKGEGKMKLGEHECDVKNGDTVFVPTGEWHEITNGSNEEMVAV
                     QITKINAGAEYRG"
     gene            complement(9338..10387)
                     /locus_tag="KOU88_002318"
     CDS             complement(9338..10387)
                     /locus_tag="KOU88_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3212192.1"
                     /translation="MFKKIVAIASSIIVSTICLTGCDFNSNDKKDESSSSKNLDKVTI
                     AEVTHSVFYAPQYAAITKGFFEDEGIKIDLINTQGADKTMAALISGEANVGLMGPEAS
                     IYVYNQNKNDYAVNFAQLTKRDGSFLVARKKMPNFSYNDLKGTEILGGRKGGVPLMTF
                     EYVLKEKGLTIGENLKAGNVNVRTDVQFGVMAGAFAGGEGDFTTAFEPTATAMEKEGS
                     GYIVTSIGKDSGEIPFTAYSTTRSYMKNNKDLIQRFTNAVYKGQLWIQQASSKEVAKA
                     MQPFFEDISLEDLTTVVDRYKSIDAWSQNPVLKEEGLKKLMTVMKEAKELDKEAPYKD
                     IVNTEFANNAIKNIK"
     gene            10773..11507
                     /locus_tag="KOU88_002319"
     CDS             10773..11507
                     /locus_tag="KOU88_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK3212193.1"
                     /translation="MKQNKYDDDRFFNKYSKMERSTNGLAGAGEWHVLKKMLPDFKGK
                     RVLDLGCGFGWHCQYAVENGAISAVGVDISEKMLKEARNKTQLDNINYICMPIEDINF
                     PKDSFDVVISSLAFHYIQSFEDICKNISNCLSNKGNFVFSVEHPIFTAYGSQEWYCDK
                     DGTNLHWPVDRYFEEGVRKSNFLGEEVIKYHKTLTTYLNTLMKTGFEILEIIEPQPEE
                     KLLDTIPDMKDELRRPMMLLVSAKKR"
     gene            complement(11650..12141)
                     /locus_tag="KOU88_002320"
     CDS             complement(11650..12141)
                     /locus_tag="KOU88_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBK3212194.1"
                     /translation="MNNQQQEVYKKLDELNIPYEAVNHPPVYTIEEMEELKTLHMEFV
                     VKNLFLRDAKGKEHFLVVLGKDKKADLKDIRQQIDSKPLSFASEERLQKYLKLTKGAV
                     TPFGILNDKEAVVKVVFDKDLLKMDKIGIHPNDNTATVFLKFEDMKKLIEENGNEIYY
                     VEV"
     gene            12490..12873
                     /locus_tag="KOU88_002321"
     CDS             12490..12873
                     /locus_tag="KOU88_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212195.1"
                     /translation="MSTDKVVGIIDEETAELAGIEYTGKIYASSGVIKHIKKKHRCQL
                     SKDIFNDIIDTIKMVLKSPEYIGSHPKKPGKSVEFIKKIDDYILVATELDTKKGYLYV
                     SSMYAIKEAKLESRVNSGRVKQYDG"
     gene            13381..13764
                     /locus_tag="KOU88_002322"
     CDS             13381..13764
                     /locus_tag="KOU88_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK3212196.1"
                     /translation="MNLSKKIEDKRKAKQRAEKVKKAKIATAGVVLGAVTGAVSGVLL
                     APKSGKETREDIKDASQQIAEKINMKTVDVKGKVSEKLEDKKGNFIESKKKIKKYIDN
                     KKSVENSSEEDKIIDIVEPVSVTEE"
     gene            13766..14116
                     /locus_tag="KOU88_002323"
     CDS             13766..14116
                     /locus_tag="KOU88_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212197.1"
                     /translation="MDNTITINISIIYVLLAILACIALVYLIIVLVKLHKILNNVGTM
                     LNENTQNINTTLNNLPNVVETFGEVGENMKDVTEVVTEVTADFLVTKDSVKSNMDVIV
                     DILTIIKNIFLDKK"
     gene            complement(14217..14675)
                     /locus_tag="KOU88_002324"
     CDS             complement(14217..14675)
                     /locus_tag="KOU88_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212198.1"
                     /translation="MIRTKVVELIATVCRENKPHKWVDENYTPYDKSGKVELMSIEDL
                     NELISSSGRADFLYSSRLQKLLKEVYINQSRASYISGCGLFWSSYWDILEEKFEEWLY
                     NSYIFFDEDDEYLEGMEDFELECKDVLMDVIETTSIDIYVQMIKRNITNY"
     gene            complement(14720..15508)
                     /locus_tag="KOU88_002325"
     CDS             complement(14720..15508)
                     /locus_tag="KOU88_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3212199.1"
                     /translation="MKVVIIPGHTLIGKGTGAVGYINESKETRILNDLIVKWLKIGGA
                     TVYTGRVDESSNHLADQCAIANKQETDLAVQIHFNSNATTSTPVGTETIYKTNNGKTY
                     AERVNTRLATVFKDRGAKSDVRGLYWLNHTIAPAILIEVCFVDSKADTDYYVNNKDKV
                     AKLIAEGILNKSISNSQGGGENKVYENVIVYTGDADKVAAQILHWQLKDSLIIEASSY
                     KQGLGKKVYVVGGEANKLVKGDVVINGADRYETVKLALQEIDKL"
     gene            complement(15647..16084)
                     /locus_tag="KOU88_002326"
     CDS             complement(15647..16084)
                     /locus_tag="KOU88_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCMP deaminase"
                     /protein_id="HBK3212200.1"
                     /translation="MNKKLENRCSWQEYFMRLCETVAERGTCDRAYVGAIIVNSENRI
                     VSTGYNGSISGDKHCSEVGHEMRDGHCIRTIHAEQNALYYCAKEGISVKDCSIYVTHF
                     PCLNCTKAIIQAGIKHIYYRTGYRIDEYAIKLLQSSNVLYTKL"
     gene            16906..17415
                     /locus_tag="KOU88_002327"
     CDS             16906..17415
                     /locus_tag="KOU88_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212201.1"
                     /translation="MLSENIKTIRKSKGLSQQELAIKLNVVRQTISKWEQGLSVPDSD
                     MLISISEVLETPVSTLLGETIVELEVDSLKVISEKLEIINFQLAQRKNMRRKMFHWLF
                     ILLCAVILIGFVVLGGLNSPYLDWNYTDPETAVFGVAFHAFEWLFVRLVPIVLIGAII
                     GIFVTRKKI"
     gene            17820..18356
                     /locus_tag="KOU88_002328"
     CDS             17820..18356
                     /locus_tag="KOU88_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBK3212202.1"
                     /translation="MQGGVNIRQVKSFVFPVISLIFLDQISKVLIGLFLMDFEIDIIG
                     KFLRFNPVQNTNLSYGGNFIGILSNLWVLVLFNILVILVIISGYAFYKSKNEQTSYSV
                     KVIMSCGLAGTICSLIDKLFWGGSLDFLQIPSFFIFDLKDCYLTVAEIIFVVIGILHN
                     REISMKEYIYFCYRQFKI"
     gene            complement(18790..19590)
                     /locus_tag="KOU88_002329"
     CDS             complement(18790..19590)
                     /locus_tag="KOU88_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212203.1"
                     /translation="MRLNKRSEGYINYVKGVKREKRNVLFYQLLILIGFIVIWELLAD
                     LNVINTFLFSKPSDIYNLFIQYAFSGQLFKHIGISVYETVLGLVIGTVLGILVAIALW
                     WSEKLSKILDPFLVVLNALPKTALAPIIIVWVGAGIEGIVVTAVTISVVVTILSAYNY
                     FMNIDEEKIKMLKSFGATKSQILFKLILPANTGNLINLTKINIGMAWVGVIVGEFLVS
                     RYGIGYLIVYGSQVFKLDLVMMGVFVLAICAWAMYAVVNIIEKIYNSR"
     gene            complement(19785..21383)
                     /locus_tag="KOU88_002330"
     CDS             complement(19785..21383)
                     /locus_tag="KOU88_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK3212204.1"
                     /translation="MKAAIYSRKSRFTGKGDSIENQIQLCIDYAKSIGVKDFLIYEDE
                     GFSGSNIDRPQFKKMMQDAKDKKFSYLVCYRLDRISRNVSDFSTLIEKLNELNISFIS
                     IKEQFDTSTPMGRAMMFISSVFAQLERETIAERIKDNMYELARSGRWLGGNTPHGFNS
                     EKITFLDENLKERSMYKLQVNDEQMEIVKLIYNKYLELRSLSKLYKYVYNNGIRGPRG
                     GKFDPSSLSRILRNPAYVKANDEILDYLKNSGMDVVGTPDRKCGILTYAKNTSNSIAA
                     IAKHHGVIEPEIWLEVQNQLDKNRDKTPRISTGKTALLSGLIKCGKCGSNMRITYKGK
                     KTDKDLKYYYICGTKKTLGSDSCNCKNLNGPLVESLVIDKIKNCKEESIISAFNSNNI
                     KTDNVFNIFKSETNLLKNQILDKERLIKNLVIELAKNTGSTASDYIVSQIESLNNEIS
                     ILKDKINTLESSNINISSDSINIDIIVSNLKRFNDEVDNASLDDKRLLLSTIINSIVW
                     DSSLGNLNIVYMGAEVDNSVSLSN"
     gene            21711..21887
                     /locus_tag="KOU88_002331"
     CDS             21711..21887
                     /locus_tag="KOU88_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212205.1"
                     /translation="MEINVIEIFPKDKAKLNKIEMDKASWFVNIISKKYPKEALNEAF
                     STLEKELNISKANT"
     gene            22061..23191
                     /locus_tag="KOU88_002332"
     CDS             22061..23191
                     /locus_tag="KOU88_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003462216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBK3212206.1"
                     /translation="MNNFEIKTRIKFGEGSLKALQELKNKNVLIITDPFMVKSKTIDK
                     ITSNLINSTYQVFEEIVPDPPIEVVVVGIEAFKSINPDVIIALGGGSAIDAAKSIMDF
                     SKKILKINEVEFIAIPTTSGTGSEVTSFAVITDSQKKCKYPLVSDDLLPDMAILDPEL
                     VKTVPNFITADTGMDVLTHAIEAYVSTNSNDFSDALAEKAIKLVFKYLIKAYKDGNDI
                     EAREKMHNASCLAGMAFNQASLGINHSIAHVLGGKFHIPHGRTNSILLPHVIEYNSSI
                     VGYTNTTYSATAKKYAQIAELVGLGSANIRISVRNLVNEIKKLQKEMNMPTKLTQCKL
                     SLEDITNEEREIAKLAIKDTCTLTNPKVPTEDDIINILKNIK"
     gene            23432..23782
                     /locus_tag="KOU88_002333"
     CDS             23432..23782
                     /locus_tag="KOU88_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBK3212207.1"
                     /translation="MTEESKQRVIQEYVPGKQVTLAHIIANPNEDIYKKLGLVLDKKD
                     AIGILTITPSEASIIAADVATKASNVSLGFIDRFSGSVVISGDVSSVESALNDVLEVL
                     GNMLNFSSTKITRT"
     gene            23790..24239
                     /locus_tag="KOU88_002334"
     CDS             23790..24239
                     /locus_tag="KOU88_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutP/PduV family microcompartment system
                     protein"
                     /protein_id="HBK3212208.1"
                     /translation="MKNIIFMGKTGSGKTTLCQKLDQLELKYKKTQSVELYNNAIDTP
                     GEYMENRNLYNALITTSADAKIIAIVYDATQEENYIAPGFASMFCKDVIGIITKINKA
                     TENEVNIAYERLSLAGASQIFKIDTVDNIGLEKLFKYLEKYKNIDEV"
     gene            24341..24916
                     /locus_tag="KOU88_002335"
     CDS             24341..24916
                     /locus_tag="KOU88_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK3212209.1"
                     /translation="MGKKILLVDDEPLLRMDTKDILESHGYEIIGEASDGFEAVEMCK
                     KHKPDLVIMDIEMPILDGIKAGKIICKENIAGGVLLLTSFEDKEYVEKAKSIGAYGYL
                     VKTASEKSLIPTIEMCLNKVNEFEKMKKDLEKVNSKLNERKLVERAKGILIREFKISE
                     DEAYTRIRKLSMDKRTTMMEIAKMIIIGYDD"
     gene            24909..26318
                     /locus_tag="KOU88_002336"
     CDS             24909..26318
                     /locus_tag="KOU88_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase N-terminal domain-containing
                     protein"
                     /protein_id="HBK3212210.1"
                     /translation="MTNTIKKISTAQTYLNNNEIEKIIEVSKSLDLMASFYEADVFID
                     VLSKFDDEAIVVAHGRPKEKSMYCENVIGKKALIENEPGVIKCLKTGERVRDIKALTQ
                     EYKLVKQNIQPITLDDKVLAVLIVEKDISSEVKNEFNASEDEENKNLHQFIKLIGNND
                     FLVDNLNSAILIFDKNGKLKIKNRIATEIYKNLGFGYDIQDMHYNDLDIETNTFENIL
                     MDENYDETNEVSIGNMFFKIKTIYIKDDEFKVCKIVQDISDLKRKEEELVLKTVAIRE
                     AHHRVKNNLHTVISIIKKQSRLSQNDEVKQCLDNIINRVFAILSTHYLLSKEVDNNIS
                     IREGINLLVSNIQGGYLFSKDIDIRITGEDFKISGEKATAILLVINEILQNCYDHAFS
                     DREHGTIQILINKDNDYRNIAIIDDGIGFDSNNINKNSLGTYIIDSYITQMLKGNIER
                     KSSENGTEVLITIPTQINI"
     gene            26502..27935
                     /gene="eutA"
                     /locus_tag="KOU88_002337"
     CDS             26502..27935
                     /gene="eutA"
                     /locus_tag="KOU88_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004458698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBK3212211.1"
                     /translation="MREELLSVGIDIGTSTTQLIFSKLIVENTESNFSVPRISIVDKE
                     IIYKSKVYFTPLISNNEINGQQIKDIVENEYKKANISKEDIHTGAVIITGETARKENA
                     NDVLHTLSGFAGDFVVATAGPDLESIISGKGAGAHIYSKEHSTTIVNIDIGGGTSNIA
                     SFKRGEVTDTGCLDIGGRLVKIDKISKKITYISPKIDKIIKDNNLNLQVGTMATVENT
                     KPIVDIMVDLLMESIGLKKQTPLFDFIITNKSISIDENIKNVSFSGGVADYIYYDGEI
                     KDYFEYGDLGILLGQAIKNCEYLKKVNVVKSMETIRATVVGAGSHTTEVSGSTITYTS
                     EKFPLKNLPVLKLSIDEETGTSKQISEAIKNKLNWFKLENDLQKVAIAMIGKKNPTFL
                     DIQEYAKGFVDGMQQIIENDLPFIVIVENDMAKVLGQAIYALLNYEKEIVCIDSVKVE
                     NGDYIDIGKPIVEGKVLPVVIKTLVFN"
     gene            27953..29317
                     /locus_tag="KOU88_002338"
     CDS             27953..29317
                     /locus_tag="KOU88_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutB"
                     /protein_id="HBK3212212.1"
                     /translation="MILNTKLFGRTYQFKGLYDVMAKANEEKSGDKLAGLAAESAEER
                     IAAKVVLSHIKLEDIRNNPAVAYEEDEVTRIIQDAVNEKVYEEIKNWTVSELREWLLD
                     SNTTSLDIRRISRGLTSEMIAAVAKLMSNMDLVYAAKKIKVTAHCNTTIGEQGTLSAR
                     LQPNHPTDDPDGILASLLEGLTFGIGDAVLGLNPVDDSVESVTKVLKRFEEVKQKYQI
                     PTQTCVLAHVTTQMEAIRNGAPADLIFQSIAGSEKGNEAFGFNGDTIEEARQLALKHG
                     TATGPNVMYFETGQGSELSSEAHHGIDQVTMEARCYGFAKKYEPFLVNTVVGFIGPEY
                     LYDAREVVRAGLEDHFMGKLHGLPMGVDVCYTNHMKADQNDMENLAILLTTAGCTYFM
                     GIPHGDDVMLNYQTTGYHETASLREMFGLTAIKEFDAWMEKMGFSKDGKLTELAGDAS
                     VLLG"
     gene            29330..30211
                     /gene="eutC"
                     /locus_tag="KOU88_002339"
     CDS             29330..30211
                     /gene="eutC"
                     /locus_tag="KOU88_002339"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014952556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit EutC"
                     /protein_id="HBK3212213.1"
                     /translation="MNEKDLKALVEQLVGQMVGELDTNVVSETVKKATEVVVDNNACI
                     DDITEVDIRKQLLVKNPKDAEAYLDMKAKTPARLGIGRAGTRYKTETVLRFRADHAAA
                     QDAVFSYVDEEFIKENNMFAVETLCKDKDEYLTRPDLGRKFSPETINNIKSKFGTNQK
                     VLILVGDGLSSAAIEANLKDCVPAIKQGLKMYGIDSSEILFVKHCRVGAMDHLGEELG
                     CEVICMLVGERPGLVTAESMSAYIAYKPYIGMAEAKRTVISNIHKGGTTAVEAGAHIA
                     ELIKTMLDKKASGIDLK"
     gene            30231..30884
                     /gene="eutL"
                     /locus_tag="KOU88_002340"
     CDS             30231..30884
                     /gene="eutL"
                     /locus_tag="KOU88_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003761789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBK3212214.1"
                     /translation="MKNDVIRPNILGIKIISNISPEMAQKLELKSHHKSLGLITADCD
                     DVTYTALDEATKASEVDVVYAKSMYAGAANASTKLAGEVLGIIAGPSPAEVRSGLNAV
                     VDFLEYGATFISANDDDSIAYYAHCVSRTGTYLSEVAGIREGEALAYLVAPPLEAMYA
                     LDAAMKAADVKMCELFAPPTETNFGGALLTGSQSACKAACDAFAEAVKSVADNPTGF"
     gene            30895..31596
                     /locus_tag="KOU88_002341"
     CDS             30895..31596
                     /locus_tag="KOU88_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBK3212215.1"
                     /translation="MDAIGLIEVIGYVAAIEASDACLKSANVNIVRVDKVGAGIVTLT
                     ICGDVGAVKAALEAGEIAASRVGTLRTSHIIPRIHNEVTNALFKTKEPKVCEVSEDKE
                     KNFEITLEIADNVSKNLSEKENVILDVNENSGDTENLYSDIDKTNKKIETVDDSLTEA
                     NEEKIENTNDKEVLEQVKIENSDFDRDDLSKNSVKKLKAMAKKLDSSITYKDLNVLKK
                     EELINLVKKLSRRDR"
     gene            31599..33068
                     /locus_tag="KOU88_002342"
     CDS             31599..33068
                     /locus_tag="KOU88_002342"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase (acetylating)"
                     /protein_id="HBK3212216.1"
                     /translation="MTLLDKDLVSIQEVRTLVRRSKVAQEKLSKMSQEQIDKIVKAVV
                     DAAFNNATKLAKMANEETGFGKWEDKVIKNTFASMGVYETLKNTKTIGIIGEDKEANT
                     IDIATPVGVVAGLIPSTNPTSTVIYKTIISLKAGNTIVFSPHPNAKNCILETVNIISD
                     AAIKAGAPEDSILCITNPSIVGTNELMKHKDTNLILATGGEAMVRAAYSSGTPAIGVG
                     PGNGPAFIDKSANVKLAIKRIIDSKTFDNGVICASEQSIVIEKSMEETVLKELKNQGA
                     YVLNEEESERLAKFILRANGTMNPQIVGKSVEVIANLADLTNVPKNTKVLVARENKVG
                     HNVAYSREKLTPILAFYVEENVEAIMNRCREILLNEGAGHTFSMHVNDEELVKRFALN
                     IPVSRILVNTPSALGGIGASTNLVPALTLGCGAIGGSSTSNNIGPLDLINVKRVAYGI
                     KEIEELGRDKSQVEKSMFDSMDKEELINLLVQKLVKELA"
     gene            33164..33451
                     /gene="eutM"
                     /locus_tag="KOU88_002343"
     CDS             33164..33451
                     /gene="eutM"
                     /locus_tag="KOU88_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBK3212217.1"
                     /translation="MASANALGMIETKGLVGAIEAADAMVKAANVQLVGKEQVGGGLV
                     TVMVRGDVGAVKAATDAGAAAAERVGELISVHVIPRPHFEVDAILPKVSAE"
     gene            33578..34339
                     /locus_tag="KOU88_002344"
     CDS             33578..34339
                     /locus_tag="KOU88_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin adenosyltransferase"
                     /protein_id="HBK3212218.1"
                     /translation="MGVLTENEVKRKIGKNKNNITEFYIEKGQIITPSAKSYLAERSI
                     ELKYVDKLSDVNNEPKEVVKEVVKEKKYKYTTVFGAKLDEKPEHMTQLNGNLLVFKDH
                     KRIILRGKIDSLESEILKVQILCQKLDMPKLVKELQEVLDFVRNIMRCEVLDEKLGDF
                     KLLGLTPQELREQSHYPKKYFGIGHEFPSYEMGEVVVAINSIRSNTREVELAAYEAFK
                     GEYGNVHREDLIKALNRLSSVFWIMIYKVRTNKYK"
     gene            34352..34981
                     /locus_tag="KOU88_002345"
     CDS             34352..34981
                     /locus_tag="KOU88_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBK3212219.1"
                     /translation="MENLLNEIVEEVITRVKKEAFIEVEASGRHVHLSREDVDKLFGE
                     RYTLTKLKDLSQPGQYACKERVTITGPKGSIKNVVVLGPCRNETQVEISLTDGSTLGL
                     KAPIKQSGDLEGTLSIKISTQYGEVELDKGLMVAKRHIHMTPKDAEKFNVCDKEIVEA
                     KVMGQRSLTFDDVVIRVSDSFKTYMHIDYDEANACGYSKGTVAKIIKKA"
     gene            35023..35748
                     /locus_tag="KOU88_002346"
     CDS             35023..35748
                     /locus_tag="KOU88_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02536 family ethanolamine utilization
                     protein"
                     /protein_id="HBK3212220.1"
                     /translation="MNYDNLVDLITEEIYKKINSNEIKISNKPKAVIVFEQDNNKFNL
                     LKDEFEIVEFDKSIRECEIVIVSRLCMRGLSNIALGNSTSDEERFILKMIMKGKKVYV
                     LDEGIEYKKYKDTAPKALYKKFMSFEDEICKFGVEIIKDLNVITKNKLNIKKELESTR
                     GSKKKDTKVLDKDVLNLTSVESVKIDNEFSLDLRNKKLISEADLRKPTINGVKNILVN
                     KKSIITPLAVDFMRIHHLKLKKL"
     gene            35761..36033
                     /locus_tag="KOU88_002347"
     CDS             35761..36033
                     /locus_tag="KOU88_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBK3212221.1"
                     /translation="MDIGKVVGNVWATRKDEKLCGQKLLVVKILKTKDTYKEGFMVAA
                     DNAGAGNGDLVLISKGSSARESIEKSHVPVDATIVGVVDSFEVFDE"
     gene            36026..36577
                     /locus_tag="KOU88_002348"
     CDS             36026..36577
                     /locus_tag="KOU88_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBK3212222.1"
                     /translation="MNKSIGAIEFKSIAKGIEVSNEMIKKSSVDVLYLKSICPGKFLI
                     IVGGETSYINECVDYGIKLGEGYIVDNFVINAISQEILDGFKNKYQKLDSIVSIGVVE
                     SSKVCAGIKMLDKTLKSGDLVLVKLQLSFAIGGKLVYIVAGDLSSLEYALKESENVVR
                     EKEVIYKTVIPSVDSQIIKSLIK"
     gene            36589..37680
                     /gene="eutH"
                     /locus_tag="KOU88_002349"
     CDS             36589..37680
                     /gene="eutH"
                     /locus_tag="KOU88_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBK3212223.1"
                     /translation="MSINEIIIYVMVVFMVLGAIDKCIGNKFGLGEQFEEGIMAMGSL
                     AVAMVGVICLAPVLADVLRPIVVPVFNILGADPAMFAGSLLANDMGGAPLALELAKDP
                     NAGLFGGLIVGAMMGPTIVFIIPVALGIIEKEDQKFLATGILAGIITIPIGAFVGGLV
                     AGFEVMMVLRNLVPIIIFAVVIALGLLKFENAMIKGFTYFGKGVVIVITLGLAAAIVE
                     ALTGIVVIPGMKPISEGIEIVGDIAIVLAGAFPLVFVITKVFNKPLMALGKVLGMNDV
                     SAAGLVASLANCIPMFGMMKDMDNRGKIINVAFSVSAAFVFGDHLGFTAGFNSNMITP
                     MIVAKLVGGITAVLLAMVIANKTLKKENV"
     gene            37682..38155
                     /locus_tag="KOU88_002350"
     CDS             37682..38155
                     /locus_tag="KOU88_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF861 domain-containing protein"
                     /protein_id="HBK3212224.1"
                     /translation="MDISNIDKNLIETLVRQIIEEKISGTKDTVDFVRNKDISGITSI
                     KLPTVKVSESDRLDTGNPSDVVYTKDLFTLEESPRLGCGMMEMKETTFDWTLNYDEID
                     YVIDGTLDIIIDGRKVSASSGELIFIPKGSKIQFSVPDYARFIYVTYPADWASQN"
     gene            complement(38275..38376)
                     /locus_tag="KOU88_002351"
                     /pseudo
     CDS             complement(38275..38376)
                     /locus_tag="KOU88_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433047.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
     gene            38671..39192
                     /locus_tag="KOU88_002352"
     CDS             38671..39192
                     /locus_tag="KOU88_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3212225.1"
                     /translation="MEEIVKKEQASMNDIFLYLKAKSNSLYKFVILYNEFINKPKDYG
                     TGELINMVEVHMLTAIEENPGISPTQLAKIWNRTKGAISQTISKLEKKGYITKEKKEG
                     NAKTILLYPTTSGVELSKAHKLYDTIDVTRTFEYLIKECTLEEIDSFYKVIDLFINLL
                     EESPQENNDSEKV"
     gene            39571..40746
                     /locus_tag="KOU88_002353"
     CDS             39571..40746
                     /locus_tag="KOU88_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3212226.1"
                     /translation="MNLKQLSEKYEEYVIQMRREFHKYPELSFKEIRTTQRIREELQK
                     IGVPFVSIEPNIVIATIQGKNEGKTIAIRGDIDALPMQEDSDVEYKSEYDGIMHSCGH
                     DAHGAMLLGLAHMLNDIRKDLKGRVLLIFQAAEEVGGGHKEIIQYFKENGGPDRLIAT
                     HVWSDIEAGKISVEPGPRMAGGSGWRIDITGRGGHGSRPDQSIDPIKPACDIVLKVSS
                     IPVNHISVLEQCVVHACAIHGGTTIGNVIPNNAEVIGGYRYFTEESGKKVFDIIKQMS
                     NGVGQVYGVDVKVTHTGGIGPVINDEEAVKMAKEIVSNIDGLELDSYEPICASDCYGE
                     ILKEYSGFYCYLGVGNKEKGIIYAQHHPKYNIDEDTLKLGCEFMAKYAVEFLNKNNN"
     gene            40780..42318
                     /locus_tag="KOU88_002354"
     CDS             40780..42318
                     /locus_tag="KOU88_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBK3212227.1"
                     /translation="MQGALKENKKKSGGGFLGWIERVGNKMPHPLALFTYITLIVVAL
                     SAIASFLGFSATSPATGKLIKVMNLISAKGLVLFMQEFVKNFQNFPVLGVVLVMAVAT
                     GVCEKTGFFSTAIKMSLSKVKGNAVVFIIAFIGVFANQAGDAAFVLVPTLAGAIFYGL
                     NRNPLAGIFCGFASVGGGFATAVIPGGWDVTLTPITVSAAQTIQPAFDMTLLASYYAL
                     FVSAFIVATVSTIVTVKFIEPKLGKYTGKPEGIDDNQGFEVTKEQAKAAKLAGFTVLA
                     YVALLIALCIPANSFLRSPEGSLIFGAPLMSCLQFFIVILFFLPGIVYGMRVGKIKTV
                     KDLNDILCQSMAAMAPFIVLAIVIGQFLTLFSVSNLAQVLAIKGGALLNSLPLPPQAI
                     ILLFLVLVAFINIFVISGSTKWMIFGPVFVPMLMQLNIHPAFTQFVYRLGDSVTNHLS
                     PLNAFFIILLATVQKYDKNAGMGTIFSAMIPYTIGYFVVLAVLVVVWMTIGIPVGIGG
                     QVWL"
     gene            42350..43552
                     /locus_tag="KOU88_002355"
     CDS             42350..43552
                     /locus_tag="KOU88_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3212228.1"
                     /translation="METTEIRYNFDEVIDRSGTNCLKYDLKSQFMPESPEDALPLWVA
                     DMDFACAPEIINAMHERIDRKIFGYSSQQTDDYYEAVCGWFKRRFDWKIEKENIFFSP
                     GVVPALGFFTQILTQKGDGIIIEKPVYYPFEDKITNNERKVVNSPLKFEDGHYSMDYD
                     GFEELAKNENNKVFILCSPHNPVGRVWKKEELRKIVDICKKYDLWIISDEIHCDIIRK
                     GEKHIPLEVACPDYKDRIITCTAPSKSFNLAGMQLSNIVINNKELQEKWMLETDSKLA
                     IFLPNPFAIVATKVAYNDCEDWMNQVNEYIDGNIKYVEDFVNEYMPKVKIIKSQGTYL
                     VWLDFRGYGLDAKQLEYVMLNKAKVLLDEGYIFGEEGAGFERINVASPRTIIEECMNR
                     IKCAFEGL"
     gene            complement(43719..44318)
                     /locus_tag="KOU88_002356"
     CDS             complement(43719..44318)
                     /locus_tag="KOU88_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3212229.1"
                     /translation="MNDNIVEVKNINMNFYTKEGELEVLKDVNFNLKEGEILTLLGPS
                     GSGKSTILNILTNLLKPTSGDIKITGNIGYMFQKDNLLEWRNIMDNITIGLEIQGKKD
                     KKSLDRVESLLKTYGLWDFRSMYPKELSGGMRQRVALIRTLSVNPDILLLDEPFSALD
                     YQTRLLVCDDVYSIIKNENKSTILVTHDIGEARYIKVQL"
     gene            44488..>45296
                     /locus_tag="KOU88_002357"
     CDS             44488..>45296
                     /locus_tag="KOU88_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212230.1"
                     /translation="MSNIITNLIESIFTNPITILFLLAITVYSVFKIIENNRVYSFVS
                     SKLDEINRDYKTSEFYKKVRDDYYTYSKENPYADVNITSFIEEVVSDLKHNNLPLLEK
                     IRSIKNSSSISILLGVLGTFVGLSTMLLCVDTKDIINSLPSTISSMQTAFTTSIFGVV
                     FSLIIGYFTKIKDCEHVLIQIMLKSENLLTSEITHFKSERMDLKVEEVKNTIKQISKS
                     IEAIEKFDKISKDLNDFNDEFISGIEALKSLLEGSQSSIKTFDQSVRKLDK"
BASE COUNT        17719 a         5630 c         7375 g        14572 t
ORIGIN      
        1 ggtgaaacat gcaatattaa ttttttaagt gatggattta tagagttgtt tggttataca
       61 agagaagaaa taaaaacatt gtttaataat gatttttata gtttaataca taaagatgat
      121 gttgaaagaa taaaaaaaga aatttttaaa caactttaca aaaataaaac tgttgaatta
      181 gaatatagga ttataacaaa aaatggtaat acagtatggg ttttagataa aggggagctt
      241 ataacagaac ctgatggaaa agaatatttt tgttgtgtaa ctgtagatat tactagaaca
      301 aaacaattag aacaagagat ggaacaaaaa aatctagaac ttgaaatgat atcagaaaat
      361 gttttaggtg gtataattat aacagaattt aatgatgatt ttactataaa atacgctaac
      421 tctggttatc tttcaatgat tggatataca cgtgaacaat tagaaaatga acttaaatac
      481 aaagcttgta atcttgtttt ttatgaagat agaaagaagg ctcttgaaag tatacaacat
      541 caattaaaca caaaaggaat agctgtatat caacatagaa taagaagaag agatggtaat
      601 attatttggg tttctataaa aggaaggctt attgttgatg atgatggtat tgaaaaaggt
      661 atttggattc taaatgatat aacagattta aaaaatgcag aacaaaaact taaaataaat
      721 gaagaaagat ttagaattgc attaaagcaa acatcaaaca ctatatttga gtatgatata
      781 aaaacaaagt cacttttaaa tactagtaaa gagcttgata aatataatat ttataaaatt
      841 actaaaaacg ttccatattc tttagtagaa tcaggagtta ttcataaaga ttttagtgat
      901 gattttataa acatgtatga aaatgtaata aatggagcaa aaaaagcaag ttgtgtagtt
      961 aagatgaaac ttccagatga aaattatata tggaataaag ttaccttgac tactattttt
     1021 gatgaagatg gtaatcctgt aagagcaatt ggtatacagg aagatataag caaacaaaag
     1081 gaagcagaga taagatacaa tcaagaaggt aagtatcatt cagctatatt gtcggaagca
     1141 atgataacct atgaaataaa tgtatcaaag gatactttta tcaaaggaaa tgaaagttgg
     1201 caaaaaccat ttggaattaa gcctgacaat aactattctc aaatggtaaa aactatagca
     1261 aatagtattg tacataaaga caataaagaa acatttttaa atacattttt atgtgaaaac
     1321 ttattggatg catataaaaa taatgtgact gaaataaaat tagaatatcg aagaatgaat
     1381 caagaaaata aaatgatttg ggtcatttgt acaatgcact taataaaaga ttctattacg
     1441 aacgatataa aagcacttgc ttatgtcaaa gatattgaca agcaaaaaaa tgaagaaatt
     1501 agattaaaat taaaagctga aagagatact cttacaggat tatataataa aggtactaca
     1561 gaaaaattga ttaatgattt cttgaactct gaggaagcaa gcttaggaat gcatgcattt
     1621 ttaattgttg atatagataa ttttaaatct gtgaatgata atttaggaca tgtatttgga
     1681 gataaagtat tatttgaagt ttctaaaaac ctaaaaccta tatttagaaa agatgatata
     1741 gtaggtagaa ttggtggaga tgaatttata gtattcttaa aaaatattca gtcttttgag
     1801 aatatcaaaa agaaagcaga aaaaatatgc gatatattta gaaattctta tacagaaaat
     1861 aaaaagacat ataaaatatc tggaacagtt ggaatttcat ttgtaccaga acatggaact
     1921 gtatttgaag aactttataa aaaagcagac atagcacttt attatgcaaa gagcaaagga
     1981 aaagataagt atgcacttta taatgattgt atctaccaaa atgaacttga aaataatata
     2041 agtgataata atataaaatt agcagataaa tgtgagaaat ccaaaccagt acttaaagaa
     2101 attcttgatt ctattgataa ttatatctat atagtgaatc caaatactta tgaacttctt
     2161 tttgtcaata ataaggtgtc tcgtttggat ttagagataa aattaggaga aacctgttat
     2221 aaatcactat taaaatctga tagaccatgt aataattgcc ctcttaacgg attagaagaa
     2281 aataagcatt caaaattcaa aatagagaca aatacatttg gtaaaaatat cagtatagca
     2341 agttggatta attgcataga tggagaatac aactgtctta tagagtgtat agattcttct
     2401 ttatacaaaa ataaataaaa aaggactatg aagatatgtt aaatagtata actttgatac
     2461 ttggtataat atttacaatt tactattttt atctcaaaat agtttttgga ggaatttcat
     2521 ttagtgagat tttcttagtt gtaggaattg tactaattat ctatcaaata tttaagaaaa
     2581 aaattaaaga aaagaaggtt ttttataggg tgttaaaaat aataatcagc atttttttaa
     2641 tagtatttgt agttactgag agtctaatta ttttttatcc caaaaatagt ttagaatcaa
     2701 aaagtgatta tctcttaatt ttaggagctt ctgtaaaaaa gactacacca agtacaaccc
     2761 tgaagggtag gttagacact gcattgaaat acctaaaaat taatgataat tgttatgtgg
     2821 tagtatctgg tggtaaagga agtggagaaa aaataactga ggcaaaagct atgaaagatt
     2881 atcttataaa aaatggtata gataaaaata ggataataga agaggataaa tccacgaata
     2941 cttatgagaa ttttaaatat tcaaaattga agatagaaga acatagtcaa ggaaaactaa
     3001 gcgatttaaa agtaaaaata gtaacaacag attttcatgt tctcagaagt aaaatattag
     3061 catatagaaa tggatataaa aatacgtctt tttatgctag taaatcaaaa ctttcatttg
     3121 taccaactta ctatacaaga gaattttttg cattatggaa aacaatcatt tttgatagat
     3181 aataaataaa aagactagat ataaactcat atctagtctt ttctattccc ttaattctaa
     3241 tccattttcc aactttactt gttgtagaaa tttcaacatt gggatttaca agtaattgct
     3301 tataagaagt tttatatttt acgattccaa aatataattt tccttcataa tccattataa
     3361 atccgaatgg tcttactctt ggtttattat cttcaactgt agcaaaatag aatgttgagt
     3421 tttctttaaa aaaattcatt attttttcat gattaaatcc tctttgtatc ttatactaat
     3481 ataatgaata taaataaaat attcataata ctaatataaa tcgatataaa aacaattaca
     3541 atattatatt gattattcaa aattatatat aaaattcaga aaaaaatttt agtttacata
     3601 ataaaaataa agtcaactaa aattattgat tttagattaa agtaccggat taagcattta
     3661 agtagatttt aagcttgatt tgattagaaa ggtacaaact atcaccgaaa aaaattaaac
     3721 ccatttaaaa agcaatataa aagcttgtta tttttgagaa aaatagaccc tctaaactca
     3781 attagattaa aaataaaata cagaaaatta tatctctaaa tatcttaaat aattaagttt
     3841 aaattttacg atattttgtt tgatgattta taatataaaa gcatactctt aatcttcaaa
     3901 atttaaaaag agtaaaaaat aacaaaaaaa tcactgacat ttcactgaca aattgtaatt
     3961 ttgttattat aaatacattg aaaatacttg attattgaaa aatggcataa aataatacat
     4021 tttatgccat ttactattat ttgatagttt ttaacttatg acataagata ttttttaaca
     4081 tatacaataa aatataaaaa aattgatatt gcaaataaaa aaaatacata ttagatgtta
     4141 tagaaaaaaa gcgcacttat aggcttaaaa tgtcacataa aagagtttta aagaataata
     4201 tattatgaac acaaattttg taatcacaaa ggagtgataa tatggcaaca gtatcaggac
     4261 aaatagtttt tgatagaaat agaagtgcta ccattgattc tggagactca ggaatagcca
     4321 atataccagt tgtattacaa gatatagcaa ctggagttag acttgtggtt ctcacagatg
     4381 catcaggaaa ttatgttttt actaatgttc caaatggtaa ctatagaatt gtagaagctt
     4441 ttggaactac aggaggagta ccaacaccag ggaattttgc aacagcgata gtaggtccag
     4501 ttccaattgc agaaatgcca cctattagtt ctgtgacaaa tcctcctatt ggttcaacaa
     4561 acttagatgg tacaacacct aacacactat taataacagt agcaggttca gatataacaa
     4621 atcaaaatat attaaatggg cctgtgattt atacacctat agagaatata ttggattctt
     4681 gcgtatctgt atctaatata aaccttatta cagatgcaga taacggaaca ttcggttttt
     4741 ttccaccagg tacaccaagt aatacaggac ctgaaataga accttaccca aatgtgacgc
     4801 cagattttac gtatgttgta ccagacccaa ctaagtttac acctttagat ggagaatata
     4861 cagtacaaaa tattatgaca aatgcaatga gtaatgttat aggagcttgg tggcgtattg
     4921 ctgaccatac tacaggaaat gaaacaggaa gaatgatggt ggtaaatggt tttaatcctg
     4981 gagctgtatt ttttaaatca acagtacaag ttacacctaa cactaattat ttatttagca
     5041 cttggatttt aaaccttttt aaggtaacag gatatccacc accacagcta ggtgtaagaa
     5101 tatttgacca aaataataat atactatatc aagcaacatt aggagctcaa attccagtta
     5161 atacaaacgc accagaatgg aaagaagtag gtactgtgat taattctcaa aataataatc
     5221 aacttacagt agaatttttt agtgaaggag aaagcgccat tggaaatgac tatgctatag
     5281 atgatgtttc tttaagagaa atagctgttc caacttttac tccaataaaa acaagtaaca
     5341 cagaaactgc taatgtaggt gatataatca catatacagt tacattagat aatacttgtg
     5401 atagcccttt aactaatgta ttttttaggg atttaattcc aaatggttta gagtttatac
     5461 ctggaactgt aacggttgat ggagtatctg tgccaggagt agaccctaat acaggtttcc
     5521 cacttccaga tattggagga ggaacagggg ttgaagtaac ttttgatgct gtggttgaaa
     5581 gtattcctaa cccaaatcct actaataata tagctaatat agattactcc tatacacctg
     5641 tagaaggcgg tataccaaat gatttttcag tagattctaa tccagttcct gttgaagtag
     5701 tatcagcaga tattgaagtt acaaaattat ctgaacctac tatagtgaat ccaggagagg
     5761 aattaatata cactataaaa gtagtaaata atggaccatt cccatctgag aatgtggttt
     5821 taacagatga tttaccagct tctattataa atccagagta ttcattagat ggaggagtaa
     5881 cttttcaacc atggaatgga agtttaaata tagggacatt agaagtagga gagacaaaag
     5941 ttattataat taggggtatt gtaaatccat caacagtagg aattataaca aatacagctg
     6001 tagtatcttc aactacagca gacccaaacc ttaataataa tacatctaca atagagacag
     6061 aagtgaattt attagcagat attttagtaa tgaaaacagc agaacctaat tcagctgttc
     6121 caggtacttt attgagatat actattcaag tagaaaactt aggaccagca aatgctgaaa
     6181 atgtaatatt aaatgatgat attccagctt ctattataaa tccagaatat tcattggatg
     6241 gaggagcaag ttttcaacca tggaatggaa gtcttaatat aggaacttta aactctggaa
     6301 tttcattaac agttttaatt caaggaacag ttagtttaaa ttcttcagaa tatatagtaa
     6361 atacagcaac agtttcttca actacacctg acccagattt aagcaacaat atatctacca
     6421 ttattacacc agttaaccca caagcaggta tttctattat aaaagtagct gacgaggatg
     6481 tagctgttcc aggagaagaa tttgtatata caattgaaat ttttaatgaa ggaccatcta
     6541 atgctacgaa tgtagtttta acagatgata tacaagatgt tattttaaat ccagaatatt
     6601 cattggatgg aggagcaact ttccaaccat ggactggaag tcttaatata ggtacagttg
     6661 caccagggca attaataaga attatcataa agggattagt aagttcaact gctacaggag
     6721 atattactaa tacagcagaa gtaagtgcag atgtaccaga accagttacg gattcatcaa
     6781 cagtgacaac tcctatagtt ccatcagcag atatagaagt aataaaaact agcaatatgg
     6841 atacagcagt tccaggagaa actttcagtt atactataac agttacaaat ttaggaccat
     6901 ctgctgcaca aagtatcgtt ttgacagatg atataccaga tgttatttta aatccagagt
     6961 attcattgga tggaggagta actttccaac catggaatgg aaatcttagt ataggcactt
     7021 tggatgctgg agaaataaga agtattataa taagaggaac agtgagccag acagcagtag
     7081 gtacaattat aaatacagca acaataagtt caactacacc tgacccaaat ccagataata
     7141 atacttcaac agatgaaaca gatataagtc cattagcaga tatttctgtg ataaaaggca
     7201 acgaaccagt tgctatacca gggggaagat ttatttatgg aattgaaatt gcaaatgcag
     7261 gaccatcttt tgcagagaac gtaactttaa cagataatat accagcttct attttaaatc
     7321 cagagtactc aatagataat ggagtgactt tccaaccatg gaatggaagc cttaatatag
     7381 gtactttaga tgctggagag ataagaaata tcataataag gggaacagta agtcaaacag
     7441 caataggcac aattataaat acagcaacag taagttcaac tacacctgac ccaaatctaa
     7501 ataacaatat ttcaacatca gaagcagagg taagttcatc agcagatatt tctgtagtaa
     7561 aacgaagcaa tcagactgtt gttgtaccag gagatgtact agactataca attgaggtga
     7621 gaaatgcagg accttctact gctcagaacg taactttaac agataatata ccagcttcta
     7681 ttttaagtcc agaatattca atagataatg gagtgatttt tcaaccatgg aatggaagtc
     7741 ttagtatagg cactttagat gctggagaga taagaaatat cataataagg ggaatagtaa
     7801 gtcaaacagc aataggtaca attataaata cagcaacagt aagttcaact acacctgacc
     7861 caaatccaga taataatact tcaacatcag aaatagatat aagttcatca gcagatattt
     7921 ctgtaataaa attagcaaat aaaacagaag catgtgtagg agagcaaata gattttgtaa
     7981 tagtagtatc aaatgcagga ccagaaaatg ctcaaaatgt tactttaata gacaatgttt
     8041 cagataagct taagaaagca gtattttcac ttgatagagg tgtaagtttc caaccatgga
     8101 ctggaagtct taatataggt acactaccag ctggaacttt aagagttatt ctattaagag
     8161 gaattataaa atcaacatgt cttgatagat taacaaatat tgcagaagtt acttcaacaa
     8221 caccagattc aaaccttaac aataatatat caagagtgca agtagaaata aaacaatgtt
     8281 gttgtaatga ttgctgttgt aacaactgta gtaattgttg ttgcaatgat tgtggttgta
     8341 aaaattgttg ctgtaattgt tgtaaaaatg acttttggtg ttgattttat aaaataattt
     8401 tgtatacctt aaattaaact gaaataaaaa ataaattcac atatgagtaa aatattttat
     8461 aaatattaat aaattttcta tctttgatat ggaccacatt cgtaatacta gttattaaat
     8521 gaagtggtcc tttttaattc attaaaatta tttattctaa ttaaatttta aatgtattaa
     8581 ataattttaa ttttttataa aaaatattga tatgttattt atattaaagt ttagatatct
     8641 aaaaatactt ttagaattta ttatattatg ttaatttttt atatcttata aggattgtat
     8701 ttttctaact ataaaaatag tattatactt atatttaaaa ataaaagaat tttattccta
     8761 ttgtgtaaag tgagaatact attttcttat attggtataa taatagtaaa tctataatat
     8821 agaaaagagg tatttctagt atgcatgaaa ataaaaagaa tctattagac ggaagcttag
     8881 ctcaatataa tgatacagca gttccaaaaa taccagtatt tgctggtaac gatataactt
     8941 cagaagttta ttattttaaa cctaatcaag ttcttaatgc tcatagacac cctaatggtg
     9001 aacaaatatt tgtgttccta aaaggagaag gtaaaatgaa acttggtgag catgaatgtg
     9061 atgtaaaaaa cggcgatact gtatttgtac caacaggaga gtggcatgaa attactaatg
     9121 gaagcaatga agaaatggta gccgttcaaa ttacaaaaat taatgctgga gcagaataca
     9181 gaggatagat atataagtac agttagtact ttaatatcta ttttattata taaactttaa
     9241 tctcaaatat aaaaagagtc ttttaaaagg ctctttttat atttttgtta attttcatta
     9301 taaaaacaag aaaatatcta gctaaaacta atatatttta tttaatattt tttatagcat
     9361 tgtttgcaaa ctcagtattt acgatatctt tataaggtgc ttccttatct agttctttag
     9421 cttctttcat aacagtcatc aatttcttca aaccttcctc ttttaataca ggattttgag
     9481 accatgcatc tattgattta tatctatcta caactgttgt taaatcttct aaagatatat
     9541 cttcaaagaa aggttgcata gccttagcta cttctttgct agatgcttgt tgaatccata
     9601 attgaccttt ataaacagca tttgtaaatc tttgaattaa atctttattg tttttcatgt
     9661 atgatctcgt agtagagtat gctgtaaaag gtatttctcc agaatctttt cctatagatg
     9721 taactatata tccactacct tctttttcca ttgctgttgc tgtaggttca aatgctgttg
     9781 taaagtcacc ctctccacct gcaaaagctc cagccattac accaaattgt acatcagttc
     9841 ttacattaac attgcctgct tttagatttt ctccaatagt aagacctttt tcttttagaa
     9901 catattcaaa agtcattagt ggaactccac cttttctacc acctaatatt tcggttcctt
     9961 ttaaatcatt gtaagagaaa ttaggcattt ttttcctagc aactagaaaa ctaccatctc
    10021 tttttgtcaa ttgagcaaag ttcactgcat aatcgttttt gttttgatta tatacatata
    10081 tagatgcttc aggacccatt aaacctacgt ttgcttcacc tgaaatcaaa gctgccatag
    10141 ttttatctgc accttgggta tttataaggt caatctttat accttcatct tcaaagaatc
    10201 ctttcgtaat agcagcatac tgtggagcat aaaaaacaga gtgagtaact tctgctatag
    10261 ttactttatc cagattttta gacgaagaag attcatcttt tttgtcatta gagttaaaat
    10321 cacatccagt tagacatatt gtacttacaa tgatagagct tgctattgcg actatttttt
    10381 taaacataat aaatacctcc cataagacat acgaatagta tatagtatta aatatttatt
    10441 gtagttgtta caaaaatgta tctatactta taatatttct acaaaaactt aataataatt
    10501 ttcagtttta tgtttagttt tttcagtaat gtgtaatatt gaataaatta tatttattat
    10561 ttataaacta agtaataaaa ttaaaataat atcacttttt tgtctattat atataaggaa
    10621 aaatttttta ataatataaa tcatattcat ttatattatt aaaaaattta tttatagaaa
    10681 cttttattat tttatataaa agtgataaaa acttatattt tgtatttaat agagtgttgc
    10741 taagtgaata tatttaaaat ggaggaaact ttatgaaaca aaataaatat gatgatgata
    10801 gattttttaa taaatacagt aaaatggaac gttctacaaa tggattagca ggtgctggag
    10861 agtggcatgt tttaaaaaaa atgttacctg atttcaaagg aaaaagagtt ttagatttag
    10921 gatgtggatt tggatggcat tgtcaatatg cagttgagaa tggagcaatt tctgctgttg
    10981 gagttgatat ttcagaaaaa atgttaaaag aagctagaaa caaaacgcaa cttgataata
    11041 taaattacat atgtatgcct attgaagata ttaattttcc aaaagatagt tttgatgtag
    11101 ttattagttc cttggcattt cattatattc aatcatttga agatatatgt aagaatataa
    11161 gtaattgtct ttcaaataaa ggtaattttg tattttctgt tgaacatcct atatttactg
    11221 catatggaag tcaagagtgg tactgtgata aagatggcac taatctacac tggccagtag
    11281 atagatattt tgaagaagga gtacgtaagt caaattttct aggagaagag gttataaaat
    11341 atcataaaac attaacaact tatttaaata cgttaatgaa aacaggattt gaaatattag
    11401 aaattattga acctcaacca gaagaaaaac tgttagatac aattcctgat atgaaagatg
    11461 agctacgtag acctatgatg ttacttgtat ctgcaaaaaa aagataagta aatataaata
    11521 atcattattg tagaaaaaaa gttgtagaaa ataattacac taatggagat gattatacca
    11581 gtggtattaa ttacatcaat agtaaggagg caaaagcatt cgttgctttt gccatttttt
    11641 aagttgcaat tatacttcta cgtagtatat ttcgtttcca ttttcttcta taagcttttt
    11701 catatcttca aattttaaaa atacagtagc agtattatca tttggatgta tacctatttt
    11761 atccattttt aataaatcct tatcaaatac aacttttaca acagcctctt tatcatttaa
    11821 tataccaaaa ggagtcacag ctcctttagt aagtttcaag tatttttgaa gtctttcttc
    11881 tgatgcaaaa ctaagaggtt tactatcaat ttgttgacga atatctttta aatctgcttt
    11941 tttgtcttta cctaatacaa ctaaaaaatg ttcttttcct ttagcatcac gaagaaatag
    12001 gttttttaca acaaattcca tatgtaatgt ttttaattct tccatttctt caattgtata
    12061 aactggtgga tgatttacag cctcataagg tatgtttaac tcatctaatt ttttatatac
    12121 ttcctgttgt tgattgttca tgatttcctc ccattagaaa tttattttat atataaataa
    12181 tattatcaca gaaaacttta aaagaaaacg ttttatataa tatagacaat agattatatt
    12241 tttataaaga agcaagaata ctcaataaaa cttaaagaaa ttaaacaatt tctaaaaata
    12301 ccttgaaaat agaaccttat ttgccattta taaattatat aaaaagggat tatataaagt
    12361 catatatgaa aaaactatat tatactatct tttctttttg gaataaacta tactttaaat
    12421 atagatattt aatttaaata aattttacag tattaatagt aaattatctt agaaaggaat
    12481 gtgctttata tgtctacaga caaagttgtt ggaatcatag atgaagaaac ggcagaactt
    12541 gcaggaattg aatatactgg taaaatttat gcttcttctg gtgttataaa acatataaag
    12601 aaaaaacata gatgtcaact gagtaaggat atttttaatg atataataga tactataaaa
    12661 atggtattaa agtcacctga atatatagga agtcatccta aaaaacctgg aaaaagtgtg
    12721 gagtttataa aaaaaattga tgattatatt ttagtagcta cagaattaga tacaaaaaaa
    12781 ggatatttat atgtatcttc aatgtatgct ataaaagaag caaaattaga aagtagagta
    12841 aacagtggaa gagtaaaaca atatgatggt taacataata ttattaattt tccctaaaat
    12901 attgaaaaat attattatat aagttataat attaatatac acgtagatat ttattagtta
    12961 gatttgaggt tggaaaaggc acccaatacg ctactataga gtagttaata gagatgcagg
    13021 atacgccgcc ctgccaaatc taattaaatt aaaaagagag gattaattcc tctcttattg
    13081 tttttttgag atactaattt aatctataat agaaagattg aaggtcgttt atacaaaaaa
    13141 attttcagtt atatacatta aactaattaa ataagatatt tataatctat atgtgataca
    13201 tattatatat taataaaaga aaaatatata gaaaatcctt ataaaaattt aaattgtaat
    13261 gaataggaag taattaaaaa gaatttttat tgatttttaa aaatttagtt agaaactata
    13321 tcattatggt aaaaaatgta ttataatgtt tagaaatatt ataataagga gcgattaaac
    13381 atgaatctat cgaagaaaat agaagataaa agaaaagcta aacagagagc tgaaaaagtt
    13441 aagaaagcta aaattgctac agctggtgtg gtattaggag ctgttactgg tgcagtgagt
    13501 ggagtacttt tggctcctaa atctggaaaa gaaacaagag aggatataaa agatgcttca
    13561 caacaaattg ctgaaaagat aaatatgaaa actgtagatg taaaaggcaa agtatctgag
    13621 aagctagagg ataaaaaagg aaactttata gaatcaaaga aaaaaataaa aaaatatata
    13681 gataacaaaa agagtgttga aaattctagt gaggaagata aaataataga tatagttgaa
    13741 ccagttagtg ttactgagga ataatatgga caatacaata acgattaaca taagtataat
    13801 atatgtatta ttagctatac ttgcttgtat tgctttagtt tatttaatta ttgtacttgt
    13861 taaactacat aagattttaa ataatgttgg aactatgtta aatgaaaata ctcaaaatat
    13921 aaatacaact ttaaataatc ttcctaatgt tgtagaaact tttggagaag taggagaaaa
    13981 tatgaaagat gtaacagaag tagttactga agttacagca gattttcttg ttactaaaga
    14041 cagtgtcaaa tcaaatatgg atgttatagt tgatatattg actataatta aaaacatttt
    14101 tctagataaa aaataataag ttaatataaa ataagcctat aagatataat ttaaacgacc
    14161 ttaaaatagc atttataagg tcgtttttta ttagcttgat ttgacactat gtgtttttaa
    14221 taattggtaa tattcctctt tatcatttga acatatatat ctatgcttgt tgtttcaatt
    14281 acatccataa gaacatcttt acattcaagc tcaaaatctt ccattccttc taaatattca
    14341 tcatcttcat caaaaaagat ataagaatta tatagccatt cttcaaattt ttcttcaagt
    14401 atatcccaat acgaactcca aaataatcca caacctgata tataagatgc tctactttga
    14461 tttatataaa cctcctttag aagcttttgt aatctactgc tataaagaaa atctgctctt
    14521 ccactgcttg atattaattc atttaaatct tctattgaca ttaattcaac tttaccactt
    14581 ttatcataag gagtataatt ttcatcaacc catttatgtg gtttgttttc tctgcatact
    14641 gttgctatca actctacaac ttttgttctt atcatttttt tatcctaact tatttatttt
    14701 ttataaaata atcatgattt tataatttat ctatttcttg taatgctaat ttaacagttt
    14761 catatctatc agcaccattt attactacat caccttttac aagtttatta gcttctccac
    14821 ctacaacata aaccttttta cctaaacctt gcttataact agacgcctca attattaaag
    14881 aatctttcaa ttgccaatgt aaaatctgag cagccacttt atcagcatca cctgtataaa
    14941 cgattacatt ttcatacact ttattttccc ctcccccttg agaatttgat atagatttgt
    15001 ttagtatacc ttctgctatc aatttagcaa ctttatcttt attattaaca taataatctg
    15061 tatctgcttt actatctaca aaacatactt ctattaatat tgctggtgca atagtatgat
    15121 taagccaata aagacctcta acatcagact ttgcacccct atctttgaat actgtagcta
    15181 acctagtatt cactctttct gcataggttt tgccattatt agtcttatat attgtttctg
    15241 tccctactgg agttgaagtt gtagcatttg aattaaaatg aatctgaaca gccaaatcag
    15301 tttcctgttt atttgctata gcacattggt ctgctaaatg attacttgat tcatcaactc
    15361 ttcctgtata aacagtagct ccacctattt taagccattt aacaattaag tcattcagta
    15421 ttcttgtttc tttgctttcg tttatatacc caacagctcc tgtacctttt ccaattaaag
    15481 tgtgccctgg tattattact actttcaaac taacatctcc tttacaatta aatttaactt
    15541 ctatttaata tatgcataac ctagaatttt gtttcttttt atatcttata cttttattat
    15601 aacccatttt gtaaaaatat agaatattaa gtaaataatg ttaaaattat aattttgtat
    15661 ataagacatt acttgattgc aataatttta tagcatattc atctattcta tatccagttc
    15721 tataatatat atgtttaatt ccagcttgaa ttatagcctt agtacaattt aagcaaggaa
    15781 agtgagttac ataaatagag caatctttaa ctgaaatacc ttcttttgca caataataaa
    15841 gggcattttg ttcagcgtga atggttctaa tacaatgtcc atctctcatt tcatgaccaa
    15901 cttcactaca atgcttatct ccagaaatac taccattata tccagtagac actattctgt
    15961 tttctgaatt aacaattata gctcctacat aagctctatc acaagttcct ctttcagcta
    16021 ctgtttcgca cagtctcata aaatattctt gccatgaaca tctattttca agttttttat
    16081 tcaaatcata tacctccaaa atttatatct aatatataag atttatacct taaaaataat
    16141 attaaaaaca aatttatacg ataaataaaa tttattaata ctgtttttag tctaaattat
    16201 ttcattttaa attaaagtta caaggaatct aaaattatat atatctttct tcgtaatatg
    16261 aatgttacaa tataaaaaac tgtctcaata aaatagagac agttttacag tcaaagttta
    16321 taatacaagt tcatattttt ctttaaattc ttttacagct tcgggccatg ccttttgttc
    16381 tgtaatacct ttttctttag ctattttaat tgcaatctct cttatcattg cagcgccttc
    16441 taatattccc atttttaatc tcccttcaaa tatctttttg tatagaatat aaatagtgct
    16501 aagatttatt acatgctgca tatacaatat ctatacaaca cataacttgt aaattccttt
    16561 tattttcata cgtctttaac cgacatataa ttatattcaa taagttttaa aattatgaac
    16621 tcaattataa ttatttttat ttttttagaa tctaaacact aaaaattgta ggtaaatttg
    16681 tcttatgcct ttataaatat ttctacagtt ttaattactg gacatatcta tttttattat
    16741 aaaaagcgct taaaaatcga gaatatccgc ataaaaactg tatataagca aaacggttaa
    16801 aggaaaaaga agaaatttac ttgaatgtta aaatgcgttg cttgaagcaa tgggcagttt
    16861 tgcctataat atcggtaaca actgaaagaa aggtggttag ccctaatgtt aagcgaaaac
    16921 attaaaacaa tcaggaagtc aaaaggactt tcacaacaag aacttgctat aaaactgaat
    16981 gtagtgcgac aaacaatatc taaatgggaa caaggactgt cagttcccga ttctgatatg
    17041 ttgatttcca tatcagaggt gcttgaaacg cccgtaagca ctttacttgg agaaactatt
    17101 gttgagttgg aagttgatag cttaaaagtg atttctgaaa aattagagat tataaacttt
    17161 caacttgcac aaagaaaaaa catgagaaga aaaatgtttc attggttatt tattttatta
    17221 tgtgcagtca tattaatagg ttttgtggtc ttagggggac taaatagtcc ttacttggat
    17281 tggaattata ccgaccctga aaccgctgtt tttggagtag cttttcatgc ttttgagtgg
    17341 ctatttgtca gattagtacc gattgtcctt ataggagcaa ttattggaat ctttgtgaca
    17401 cgtaagaaaa tatgaagtaa ctctgctttt tataatacag caagcgttcc ttaaaagcgt
    17461 cattctacat ggcaatcgag gacgactatg taaggaagaa cctttttgat ttccaactaa
    17521 gcgaagttat tgaggacgac agtaggctca aaaccgcatt aagtaaagta caggaagcaa
    17581 gactgctgga cttatactct catgcgtcag atgcaggaaa tgcgaggtct ggtagcatga
    17641 tttacaacga tttgtacaac gactacgagt agaaatatat ggagataagt attatctacg
    17701 aaatcagaaa agaaatgact tgataattta cccatgttat aattattgat gtgaaattaa
    17761 taaatcgaaa ttcctttttt agatttaaca atactgagta aggaaaaagt gaatgacttt
    17821 tgcaaggagg tgttaatatc aggcaagtaa agtcttttgt ttttccagtt atatccttaa
    17881 tattcttaga ccaaattagc aaagttctta taggattatt cttaatggac tttgaaattg
    17941 atataattgg gaaattttta agattcaatc ctgttcaaaa tacaaatctc tcttatgggg
    18001 gaaactttat tggtattcta tctaatttat gggtattggt attgtttaac attttagtta
    18061 tattagttat tatatctgga tatgcttttt ataaatcaaa aaatgaacaa acaagctatt
    18121 cagtaaaagt aattatgtct tgtggacttg ctggtacaat atgtagcttg atagataaat
    18181 tattttgggg aggaagttta gattttttgc agataccaag cttttttatt ttcgacttaa
    18241 aagactgcta ccttactgtt gcagaaataa tatttgttgt cataggaatt ttgcataata
    18301 gagaaatatc aatgaaagaa tacatatatt tttgctatcg tcagtttaaa atataaattt
    18361 agaagataaa tttaagtttc aaggtaaact tatttaatca cagcaaatag ttggcttact
    18421 taagcttttg ggctaaactg tgagcactaa ttaagtctct gctatctaac aaacggagca
    18481 caaaaataaa aattaaatat taaatataaa gcacagttaa ttttgattaa aaagttgact
    18541 gtcttttctt ttgtagaaat ttaagcatag gtaataaaga aatgactgca tttaagcatt
    18601 atgtatataa ttggaggcaa taaaaagcca gcaaagccca taaaatagag ctgtgctagc
    18661 aacatgatga gttataagaa gataatcaaa aacttacgct ttattttaat ttaaaaaaat
    18721 gattactgta aagaaatcat tttttattat aatcactgat acatcaaata ttctaaataa
    18781 aatttttatt tatctggaat tgtatatttt ttctataata ttaactacag cgtacattgc
    18841 ccaagcacag atagccaata caaatactcc catcattact aaatctaatt taaatacttg
    18901 agaaccatat actatcaagt agcctattcc atatcttgaa actaaaaatt ctccaactat
    18961 tacacctacc catgccatac caatattaat tttagttaaa tttattaaat ttcctgtgtt
    19021 tgcaggtaat atgagtttaa ataatatttg agatttagta gctccaaagc tttttaacat
    19081 cttaattttt tcttcatcta tattcataaa ataattataa gctgaaagta tagtaacaac
    19141 aacagaaatc gttacagctg ttacgacgat tccttctatt ccagcaccta cccaaactat
    19201 aattatagga gctaaagcag tcttaggaag agcatttaaa actaccaaaa atgggtctaa
    19261 tatttttgat aatttttctg accaccaaag agcaattgct accaaaatac ctaatacagt
    19321 acctataaca agaccaagaa cagtttcata tacagatatt ccaatatgtt taaataattg
    19381 accactaaat gcatattgaa taaataaatt gtaaatatca cttggtttgc taaatagaaa
    19441 tgtatttata acatttaagt cagctaaaag ttcccagatt acaataaaac caattaaaat
    19501 taatagctgg tagaataata catttctttt ttctcttttt acacctttaa catagtttat
    19561 atatccttca gatcttttat taagcctcat gtgtatctag ctccttccat aatatgtcga
    19621 aatacttttg aaaatcagga actttacgtg ttttgagagg cgtttttgtt ccatccatgt
    19681 taagttcaat atcgtaaata ttttttatgg tagctggtct tttagatagt attgcaacct
    19741 tatctgatat gcttattgct tctgctatag ctaaaaaagt gcaactaatt gcttaaagaa
    19801 acagaattat ccacttcagc acccatataa acaatattaa gatttcctaa actgctatcc
    19861 caaacgatac tattaataat agtagataat aacaatctct tatcatctaa actggcatta
    19921 tcaacttcat cattaaatct cttcaaatta ctaacaataa tatcaatatt aatactgtca
    19981 ctactaatat tgatgttact agattccaaa gtattaatct tatcctttaa aatactaatc
    20041 tcattattta ggctctcaat ctgggaaact atataatcag aagcagtact accagtattt
    20101 tttgcaagct ctataactaa atttttaata agtctttcct tatctaaaat ttgattttta
    20161 agtaaattag tctcagattt aaaaatatta aaaacattat cagtcttaat gttattacta
    20221 ttgaatgcac ttataataga ctcttcttta caattcttaa ttttatctat aactaaactt
    20281 tcaactaatg gaccattaag atttttacag ttgcaactat cagacccaag tgttttttta
    20341 gtaccacaaa tataataata ctttaaatcc ttgtcagttt ttttgccttt ataggtaatt
    20401 ctcatattag aaccacattt accacatttt ataagaccag ataaaagagc agtttttcca
    20461 gttgatatcc ttggagtttt atcacgattt ttatctaatt gattttgtac ttcaagccat
    20521 atttcaggtt ctatgactcc atggtgtttt gcaattgctg ctattgagtt agatgtattt
    20581 ttagcatagg taaggattcc acattttcta tctggagtac ctacaacatc cataccacta
    20641 tttttaaggt aatctaaaat ttcatcatta gcttttacat atgctggatt tctaagtatt
    20701 ctagataaag aactagggtc aaatttacca ccacgaggac cccttattcc attattatag
    20761 acatatttat ataacttaga taaggaccta agttctaaat atttattgta tattagcttt
    20821 acaatctcca tttgttcatc atttacttga agcttataca tacttctttc ttttagattt
    20881 tcatctaaga atgtgatttt ttcactgttg aatccatgag gtgtattgcc tccaagccat
    20941 ctaccactac gggctaattc atacatattg tcttttatac gttctgctat tgtttctctt
    21001 tctaattgag caaatacact tgatataaac atcatagctc ttcccattgg agttgaagta
    21061 tcaaattgtt ctttgataga tataaatgat atgtttagtt catttaattt ttctattaaa
    21121 gtagagaagt cagatacatt tctcgatatc ctatctaatc tataacaaac taggtaacta
    21181 aatttcttat ctttggcatc ctgcatcatt ttcttaaatt gtggtctatc tatattgcta
    21241 ccactaaatc cctcatcttc atatatcaaa aaatctttta caccaataga ctttgcataa
    21301 tcaatacata attgtatttg attttctata gaatcacctt ttccagtaaa tcttgatttt
    21361 cttgaataaa ttgcagcttt caaaattaaa acctcctata agttaggata tatatttgaa
    21421 actatttatc tacaaccttt taagtaaact tattagaatg aatttattaa ttaggtaaat
    21481 ttatataatt ctacttttta taatatatga ctatttattt tatttcttta ctattcaagt
    21541 tctaaatcaa taataaattt tgatatttaa ttgtatcagg acaaatctct aatttcatag
    21601 attattaata taaaatcata ggttagtgtg aaaaagttga aatttaaata ttttaaaaga
    21661 taattttttt gaactaatag gtataacaaa aatttatagg gggattgcat atggaaatca
    21721 atgttataga aattttccct aaagataaag ctaaacttaa taaaatagaa atggataaag
    21781 ctagttggtt tgtaaatata ataagtaaaa aatatcctaa agaagcttta aatgaagcat
    21841 ttagtacttt agaaaaagaa ttaaatataa gtaaagctaa tacataagct ttgattattg
    21901 attttatata ctattggttt tatacactat gacttgacat tatattaatc aaatagtata
    21961 tttttaaata tagcacaatg aagtgttaaa agagcaatgg agctccatag ataaagtcta
    22021 tggagctttt ttgcgtattt aacttaagga ggataggact ttgaataact ttgagattaa
    22081 aactagaata aaatttggag aaggctcact aaaagctttg caagaattaa aaaacaaaaa
    22141 tgtactaata ataacagacc cttttatggt gaaatcaaaa acaatagata aaataacatc
    22201 taatttaata aactcaacat atcaagtttt tgaagaaata gtaccagacc caccaataga
    22261 agtagtagta gtaggaatag aagcatttaa atctataaat ccagacgtaa taatagcatt
    22321 aggtggtggt tctgcaatag atgcagcaaa atctataatg gacttttcta aaaaaatatt
    22381 aaaaattaac gaagtagagt ttatagcaat accaacaaca agtggaacag gttcagaagt
    22441 aacatcattt gctgtaataa cagatagtca aaaaaaatgt aagtatccat tagtgagtga
    22501 tgatttactt ccagatatgg caatactaga cccagaactt gtaaaaactg taccaaattt
    22561 tataacagca gatacaggga tggatgtatt gacacatgct atagaagctt acgtatctac
    22621 aaattctaat gacttttcag atgcactagc tgaaaaagct ataaagttag tatttaaata
    22681 cttaataaaa gcatataaag atggaaatga catagaagct agagaaaaaa tgcacaatgc
    22741 atcttgttta gcaggtatgg catttaacca agcatcactt ggcataaatc attctattgc
    22801 acatgtatta ggtggaaaat tccatatacc acatggaaga acaaactcta tattacttcc
    22861 tcatgtaata gaatataatt catcaatagt aggatatact aacacaactt actctgctac
    22921 agctaaaaaa tatgcacaaa tagcagaatt agtaggactt gggagtgcta atataagaat
    22981 atctgttaga aatttagtaa atgaaataaa gaaactacaa aaagaaatga atatgccaac
    23041 taaattgaca caatgcaaat taagtttaga agatataact aatgaagaaa gagaaatagc
    23101 aaaacttgct ataaaagata cttgtacatt aactaatcct aaggtaccaa ctgaagatga
    23161 tataataaac atattaaaga acattaaata actacatttt attacatgta aatataatat
    23221 tatacaaata gggaaaatgt ttttaaaaat ataaattata tattgacaaa tataaaacat
    23281 aaaactataa tgaaagtatc acaaaggcgt gatactttag tagaaagcaa tggagcttct
    23341 taggaatatt aatattattc ttatggagct ccttttattt taatcaaata gctttttaat
    23401 aaactatatt caaagaaagc agggaataaa tttgactgaa gaatctaagc aaagagttat
    23461 tcaagaatat gttcctggaa aacaggttac attagcacat atcatagcta accctaatga
    23521 agatatatat aagaagttag gattagtact tgataaaaaa gatgcaatag gaatacttac
    23581 aataacacca agtgaagcgt caataatagc agcagatgtt gctacaaagg cttcaaatgt
    23641 atctttaggt tttatagata gatttagtgg ttcagtagta atatcaggtg atgtaagttc
    23701 tgtagaatca gcgttaaatg atgttttaga agtcttagga aatatgttaa acttctcatc
    23761 tacaaaaatc acaaggacat aataatacaa tgaagaatat aatatttatg ggaaagacag
    23821 gtagtggtaa aactacctta tgtcaaaaac tagaccagtt agaattaaag tataaaaaaa
    23881 ctcaatcagt ggaactttat aataatgcaa tagacactcc tggtgagtat atggaaaata
    23941 gaaacctata taatgcctta ataacaacat cagcagatgc taaaattata gcaatagtgt
    24001 atgatgccac acaagaagaa aattatatag caccaggttt tgccagtatg ttttgcaaag
    24061 acgtaatagg aattataact aaaataaata aagctactga aaacgaagtc aatatagctt
    24121 atgaaagact atcactagca ggagcaagtc aaatctttaa aatagacaca gttgataata
    24181 ttggacttga aaaattattt aaatatctag aaaaatataa aaatatagat gaagtttaag
    24241 gggaaatatt tttttattca aaaatattat taaagtatga taaaataaaa aaatgtataa
    24301 actattttaa gaagatttaa tctttaagcg aggtaggaac atggggaaaa aaatactatt
    24361 ggttgatgat gaaccactgt taaggatgga tacaaaagat atattagaaa gtcatggcta
    24421 tgaaataata ggcgaagcaa gtgatggatt tgaagctgtt gaaatgtgta aaaaacacaa
    24481 acctgattta gttataatgg atatagagat gccaatactt gatggtataa aggcaggcaa
    24541 aataatatgt aaagaaaata tagctggtgg agtactttta ttaacttcat ttgaagataa
    24601 agaatacgta gaaaaggcta aaagtatagg tgcttatgga tatttagtaa aaacagcaag
    24661 tgaaaaatca cttatcccaa ccatagaaat gtgtttaaat aaggtaaatg aatttgaaaa
    24721 aatgaaaaaa gatttagaaa aagtaaattc taaattgaat gaaagaaaat tagtagaaag
    24781 agcaaaaggt atacttataa gagagtttaa gatttctgag gatgaagcat acactagaat
    24841 aagaaaatta agtatggata aaagaactac aatgatggaa attgccaaaa tgattataat
    24901 aggatacgat gactaatacg ataaaaaaaa tatcaactgc acaaacatac ttaaataata
    24961 acgaaattga aaaaattata gaagtatcaa aatccttaga tttaatggct tctttttatg
    25021 aagctgatgt ttttatagat gtactaagta aatttgatga tgaagcaatt gttgtggcac
    25081 atggtagacc taaagaaaag tcaatgtact gtgaaaatgt tataggtaaa aaggctttaa
    25141 ttgaaaatga accaggagtt ataaagtgct taaaaacagg agaaagagta agagatatta
    25201 aagctttaac acaggaatat aaactggtca aacaaaatat tcagccaata acactagatg
    25261 acaaagtttt agcagtacta atagttgaaa aagatataag tagtgaagtt aagaatgagt
    25321 ttaatgctag tgaagacgaa gaaaataaaa atttacatca gtttataaaa cttattggaa
    25381 ataatgactt tttagttgat aatttaaatt cagccatatt aatatttgat aaaaatggaa
    25441 aattaaaaat taaaaatcgt attgcaactg agatatacaa aaatcttggg tttggatatg
    25501 atatacaaga tatgcattac aatgatttag atatagaaac caacaccttt gaaaatatat
    25561 taatggatga aaattatgat gagacaaatg aagtttcaat aggtaatatg ttttttaaaa
    25621 taaagaccat atacatcaaa gatgatgaat ttaaggtttg caaaatagta caagatataa
    25681 gtgatttaaa gagaaaagaa gaagaattag ttttgaaaac agtggctata agagaagctc
    25741 atcatagagt aaaaaataat cttcatacag taatatctat aataaaaaaa caaagtagat
    25801 tatctcaaaa tgatgaagta aagcagtgtt tagataacat aataaatagg gtatttgcaa
    25861 tactttcgac tcattattta ctatctaaag aagttgataa taatatatct atacgagaag
    25921 gtatcaattt attagtgtca aatattcaag gtggctattt atttagtaag gatatagata
    25981 tacgtataac tggtgaagat tttaaaatta gtggagaaaa agcaacagca atacttttgg
    26041 ttataaatga aatactacaa aattgttatg accatgcatt ttcggataga gaacatggta
    26101 ctatacaaat attaataaat aaagataacg actatagaaa tattgctatt atagatgatg
    26161 gaattggatt tgatagtaat aatataaata aaaatagctt agggacatat ataatagata
    26221 gttatataac acagatgtta aaaggaaata tagagagaaa aagtagtgag aatggtacag
    26281 aagtattaat tactatacct acacaaatta atatttaaat aataactcat ctacaaagta
    26341 gtagttttaa ttgagcaaag aggcttaagg ttattaatag attaagttaa ttgaatgtat
    26401 ttataaaaat tataagtata tattcaattt aacaggtatt tattataact ttaagcctct
    26461 ttgcttgttt aagacatact taaattttag gaggtgagaa aatgagagaa gagttattaa
    26521 gtgttggtat tgacattgga acaagtacta ctcagttaat tttttctaaa ttaatagtag
    26581 aaaatactga atcaaatttt tcggtaccta gaataagtat agtagacaaa gaaattattt
    26641 ataaaagcaa agtttatttc acccctctta tttcaaataa tgaaataaat ggtcaacaaa
    26701 taaaagatat agttgaaaat gaatataaaa aagcaaatat atctaaagaa gatatacata
    26761 caggagcagt aataataact ggtgaaacag ctagaaaaga aaatgcaaat gatgtacttc
    26821 atactttgag tggatttgct ggggacttcg ttgttgcaac agcaggacct gatttagaaa
    26881 gtataatatc aggaaaagga gctggagctc atatttattc aaaagaacat tcaactacaa
    26941 ttgtaaatat agacataggt gggggaacta gtaacatagc ctcatttaaa aggggagaag
    27001 taaccgatac tgggtgtttg gatataggtg gaaggcttgt aaagatagat aaaataagta
    27061 aaaaaataac ttatatatca cctaaaatag ataaaatcat aaaagataat aatttaaatc
    27121 ttcaagtagg cacaatggct actgtagaaa atacaaagcc aatagtggat ataatggttg
    27181 acttattaat ggaaagcata ggattaaaga aacagacacc tttgtttgat tttataataa
    27241 ccaataaatc aataagtata gatgaaaata ttaaaaatgt ttcattctct ggtggagtag
    27301 ctgattatat ttactatgat ggagaaataa aagattattt tgaatatggt gacttgggaa
    27361 ttttacttgg gcaagcaata aaaaattgtg aataccttaa aaaagtaaat gtagttaaat
    27421 ctatggaaac aataagagcc acagtggttg gagcaggttc tcatactact gaagtaagtg
    27481 gaagtacaat aacttacact agcgaaaagt ttccacttaa gaacttgcca gttttaaaat
    27541 tatcaattga tgaagaaaca ggcacttcaa aacaaatcag tgaagctata aaaaataaac
    27601 ttaattggtt taaactagaa aatgatttac agaaagttgc tatagccatg ataggaaaga
    27661 aaaatccaac ctttttagat atacaagagt atgctaaagg gtttgtagat ggaatgcaac
    27721 aaatcataga aaatgattta ccttttatag taattgttga aaatgatatg gcaaaagtgt
    27781 taggtcaagc aatatatgca ttattaaatt atgaaaaaga aattgtttgt atagacagtg
    27841 tcaaggttga aaatggagac tatatcgaca ttggaaaacc tatagttgaa ggtaaagttt
    27901 tacctgtggt aataaaaaca ttagttttta attaatagaa ggaggtaagt aaatgatttt
    27961 aaatacaaaa ttatttggac gtacttatca gtttaaaggc ttatatgatg taatggctaa
    28021 agctaatgaa gaaaaatcag gagataaatt agcaggtctt gcagcagaat cagctgaaga
    28081 aagaatagca gcaaaagttg ttttatcaca cataaaattg gaggatataa gaaataatcc
    28141 tgcagtggca tatgaagaag atgaagtaac aagaataata caagatgctg taaatgaaaa
    28201 agtttatgaa gaaataaaaa attggacagt ctctgaactt agagaatggc tattggattc
    28261 aaatactaca agtcttgata taagaagaat atcaagagga ttaacttctg aaatgatagc
    28321 agcagttgca aaattaatgt caaatatgga cttagtttat gcagctaaaa agataaaggt
    28381 tactgctcac tgtaatacaa ctataggaga acaaggaaca ttatcagcaa gacttcaacc
    28441 taatcatcca acagacgacc cagatggaat acttgcatca cttcttgaag gtttaacttt
    28501 tggtatagga gatgcagtac ttggattaaa tccagttgat gactctgttg agagtgttac
    28561 taaagtatta aaaagatttg aagaagtaaa acaaaaatat caaataccaa ctcaaacatg
    28621 tgtattggca cacgttacta cacaaatgga agcaataaga aatggtgctc ctgcagattt
    28681 aatattccaa tctatagcag gttctgaaaa aggaaatgaa gcatttggat ttaatggcga
    28741 cactatagaa gaagctagac agttagcctt aaaacacggt acagctacag gacctaacgt
    28801 tatgtatttt gaaactggac aaggttcaga attatcttca gaagcacatc atggaataga
    28861 ccaagttact atggaagcta gatgctatgg atttgctaaa aagtatgaac cattcttagt
    28921 aaatacagtt gttgggttta taggacctga gtacttatat gatgctagag aagttgtaag
    28981 agcaggactt gaagaccact ttatgggtaa actacatggc ttaccaatgg gtgttgatgt
    29041 ttgttacact aaccatatga aggctgacca aaatgatatg gaaaacttag ccatactatt
    29101 aacaacagca ggatgtacgt attttatggg aatacctcat ggagatgatg ttatgcttaa
    29161 ctatcaaaca acaggatacc atgaaacagc atcacttaga gaaatgtttg gactaacagc
    29221 aataaaagaa tttgatgctt ggatggaaaa gatgggattc tctaaagatg gtaagttaac
    29281 agagttggcg ggagacgcat ctgtattatt aggataggag gtatttaata tgaatgagaa
    29341 ggatttaaaa gcattggtag aacaattagt tggacaaatg gttggagaat tagatactaa
    29401 tgttgtgtct gagactgtta aaaaggcaac tgaagttgta gtagacaaca atgcttgtat
    29461 agatgatata acagaagttg atataagaaa gcaattacta gtaaaaaatc ctaaggatgc
    29521 agaagcttat ttagatatga aagcaaaaac acctgcaaga ttaggtatag gaagagctgg
    29581 tactagatat aaaacagaaa cagttttaag atttagagca gaccatgctg ctgcacaaga
    29641 tgctgtattc tcttatgtag atgaagaatt tataaaagaa aataatatgt ttgcagtgga
    29701 aactttatgt aaagataaag atgaatactt aacaagacca gatttgggaa gaaaattttc
    29761 tccagaaact ataaataata taaaatctaa atttggtaca aatcaaaagg ttttaatatt
    29821 agttggagat gggcttagct cagctgcaat agaggcaaat ttaaaagact gtgtgccagc
    29881 tataaaacag gggctaaaaa tgtatggtat agattcaagt gaaattttat ttgttaaaca
    29941 ttgtagagtt ggtgctatgg accacttagg tgaagaatta ggttgtgaag ttatatgtat
    30001 gttggttgga gaaagaccag gattagttac tgctgaatca atgtcagcat atatagctta
    30061 taagccatat ataggaatgg cagaagcaaa aagaacagtt atatcaaata ttcacaaagg
    30121 tggaacaact gcagttgaag caggtgctca tatagctgaa cttataaaaa ctatgttaga
    30181 taaaaaagct tcaggaatag accttaaata aagtcgaggg agtgtagaat atgaaaaatg
    30241 atgtaattcg tcctaatata ctaggaatta aaataatttc aaatataagt ccagaaatgg
    30301 cacaaaaact agaattaaaa tcacatcaca aaagcttagg tttaataact gcagactgtg
    30361 atgatgttac gtatacagct cttgacgaag caactaaagc ttcagaagtt gatgttgtat
    30421 atgcaaaatc aatgtatgca ggtgctgcaa atgcttcaac aaaacttgct ggtgaagtat
    30481 taggaataat agcaggtcca agcccagcag aagtaagaag tggtctaaat gcagtagttg
    30541 attttctaga gtatggagca acttttataa gtgcaaatga tgatgattca atagcatact
    30601 atgctcactg cgtatcaaga acaggtacat acctttcaga ggtagcagga ataagagaag
    30661 gtgaagcatt agcttattta gtagcaccac cacttgaagc aatgtatgca ctagatgcag
    30721 caatgaaagc tgcagatgtt aagatgtgtg aattatttgc acctccaact gaaacaaact
    30781 ttggtggagc attacttaca ggttctcaat cggcttgtaa agcagcatgt gatgcatttg
    30841 cagaagcagt aaaatcagtt gcagacaatc caacaggatt ttaaggatag ttagatggat
    30901 gctataggct taatagaagt aataggatat gttgctgcaa tagaagcttc tgatgcttgt
    30961 ttaaaatctg caaatgttaa tattgtaaga gttgataagg ttggagcagg tattgttact
    31021 ttaacaatat gtggagatgt cggtgctgta aaagctgctt tagaagcagg tgaaatagca
    31081 gcttccagag ttggtacatt aagaacatca catattatac cgagaatcca taatgaagta
    31141 acaaatgctt tattcaaaac taaagaacct aaagtctgtg aagtttcaga agataaagaa
    31201 aaaaactttg agattacatt ggaaatagct gataatgtat cgaaaaattt atcagaaaaa
    31261 gaaaatgtaa ttttagatgt caatgaaaac agtggagata ctgaaaattt atatagtgat
    31321 atagataaaa caaacaaaaa aattgaaaca gttgatgata gtttaacaga agctaatgag
    31381 gaaaaaatag aaaacactaa tgataaagaa gtattggaac aagttaaaat agaaaattcc
    31441 gattttgata gagatgacct atcaaagaac agtgtaaaaa aacttaaagc tatggctaag
    31501 aaattagatt cttcaataac ttataaagac ttaaatgttc ttaaaaaaga agaattaata
    31561 aacttagtta aaaagcttag tagaagggat agatagttat gacactttta gataaagatt
    31621 tagtatctat acaagaagta agaactcttg taagaagatc taaagtggct caagagaaac
    31681 tttctaaaat gagtcaagag caaatagata aaatagtaaa agctgttgta gatgcagcat
    31741 ttaataatgc tactaaatta gctaaaatgg caaatgaaga aactggattt ggaaaatggg
    31801 aagataaagt aattaaaaat acttttgcat ctatgggagt ttatgaaact ttaaagaaca
    31861 caaaaactat tggaataatt ggtgaagata aagaagccaa tacgatagat atagctacac
    31921 cagttggagt tgttgcaggt cttatacctt caacaaaccc aacatcaaca gtaatataca
    31981 aaactataat atctctaaaa gcaggaaata ctatagtttt ctctccacat ccaaatgcaa
    32041 aaaactgcat acttgaaaca gttaatataa taagtgatgc tgctataaag gctggagctc
    32101 cagaggattc aatattatgt ataactaatc caagtatagt tggaaccaat gaattgatga
    32161 aacataaaga tacaaactta atactagcaa ctggaggaga agcaatggtt agagctgctt
    32221 actcttcagg aacaccagct attggagttg gaccaggaaa tggaccagca tttatagata
    32281 aatcagcaaa tgttaaatta gcaatcaaaa gaataataga ttctaaaact tttgataatg
    32341 gtgttatatg tgcatcagaa caatctatag taatagaaaa atctatggaa gaaactgttt
    32401 taaaagagct taaaaatcaa ggtgcatatg ttttaaatga ggaggaaagt gaaagattag
    32461 caaaattcat attaagagct aatggtacta tgaatccaca aatagttggt aaaagtgttg
    32521 aggtaatagc aaatttagca gacttaacaa atgtacctaa aaatacaaaa gttctagttg
    32581 caagagaaaa taaagttggt cacaatgtag cctattcaag agaaaaactt acaccaatac
    32641 tagcgttcta tgttgaagaa aatgtagaag ctattatgaa cagatgcaga gaaatattgt
    32701 taaatgaagg tgcaggtcat acattctcaa tgcatgtaaa tgatgaagaa ttggtaaaaa
    32761 gatttgccct taatatacca gtatcaagaa tacttgtgaa tactccttca gcacttggag
    32821 gaataggtgc atcaacaaac cttgtaccag cactaacact tggttgtggt gcaataggtg
    32881 gaagttcaac ttcaaacaat ataggaccac ttgatttaat aaatgttaaa agagtagctt
    32941 atggaatcaa agaaatagaa gaacttggaa gagataaatc tcaagttgaa aaatcaatgt
    33001 ttgactcaat ggataaagaa gaattaataa atcttcttgt tcaaaaacta gtcaaagaac
    33061 tagcataact aaaataaaca atgaaactta tggctatcgc tataaatttc taaaaatata
    33121 aactataaaa aactataaaa ttaaattttt ggaggataag attatggcaa gtgcaaacgc
    33181 attaggaatg atagaaacta aaggattagt aggagcaata gaagcagcag atgcaatggt
    33241 taaagctgca aatgtacaat tagtaggaaa agagcaagta ggtggaggat tagttactgt
    33301 aatggtaaga ggagatgttg gagctgttaa agctgctaca gatgcaggag ctgccgctgc
    33361 cgagagagtt ggagaactaa tatcagttca tgttatacca agaccacact ttgaagtaga
    33421 tgctatatta ccaaaggtat cagctgagta atataagaat aattataaaa tttaaatttt
    33481 gattgaaaaa gaggctatct caaaaatgag tcttactaat aaactcaatg tattttgagg
    33541 tagtcttttt tatacatcta ataggagatg tgataaaatg ggtgttttaa cagaaaacga
    33601 agtaaaaaga aaaattggaa aaaacaaaaa taatataact gaattttata tagaaaaagg
    33661 tcaaataata actccttctg caaaatctta tttagctgag agaagtattg agcttaaata
    33721 tgttgataaa ctttcagatg taaacaatga acctaaagaa gttgtaaaag aagtagttaa
    33781 agagaaaaaa tataaatata ctactgtatt tggcgccaaa ttggatgaaa aaccagaaca
    33841 tatgactcaa ttaaatggaa atcttttagt ttttaaagac cataaaagaa taatattgag
    33901 aggaaaaata gattctcttg aatcagaaat actaaaggta cagatacttt gtcaaaaact
    33961 agatatgcca aagcttgtta aggaattgca agaagtatta gactttgtaa gaaatataat
    34021 gagatgtgaa gttttagatg aaaagctagg ggactttaaa cttttaggat taactcctca
    34081 agaacttaga gaacaatctc actatcctaa aaaatacttt ggtataggac atgagttccc
    34141 aagttatgaa atgggagaag tagtagtagc tataaatagt ataagaagta atacacgaga
    34201 ggttgaactt gcagcctatg aagcatttaa gggtgagtat ggaaatgttc acagagaaga
    34261 tttaataaag gcacttaata gattatcgtc agtattttgg ataatgatat ataaggttag
    34321 aactaataag tataagtagt tggaggacat aatggagaat ctattaaatg aaatagtgga
    34381 agaagtaata actagagtta aaaaagaagc atttatagaa gttgaagcat caggaagaca
    34441 cgttcactta agtagagaag atgtcgataa attatttgga gaaagatata ctcttacaaa
    34501 actaaaagac ctatctcaac caggtcaata tgcatgtaag gaaagagtta caataactgg
    34561 tcctaaagga agtataaaaa atgtagttgt acttggacca tgtagaaatg aaactcaggt
    34621 agaaatatct ttaacagatg gttcaactct tggactaaaa gctcctataa aacaaagtgg
    34681 agacttagaa ggtactttaa gtattaaaat atcaacacaa tatggtgaag ttgaacttga
    34741 taaggggcta atggttgcta aaagacatat acacatgact cctaaagatg ctgaaaaatt
    34801 caatgtatgt gataaagaga tagttgaagc taaggtgatg ggtcaaagat ctttaacatt
    34861 tgatgatgta gtaataagag tgagtgacag ttttaaaact tatatgcata tagactatga
    34921 tgaagccaat gcatgtggtt attcaaaagg aactgttgct aaaataataa agaaagcata
    34981 aatttaacct actatataaa ttacctctag ggaggattta atatgaatta tgataacctt
    35041 gtagatttaa taacggaaga aatctataaa aaaataaata gtaatgaaat aaaaatatct
    35101 aataaaccta aagctgtgat tgtatttgaa caagataaca ataaatttaa cttattaaaa
    35161 gatgaatttg aaatagtaga atttgataaa agtataaggg aatgtgaaat agtgatagtt
    35221 tcaagacttt gtatgagggg actatcgaat atagcacttg gaaattcaac aagtgatgaa
    35281 gaaagattta tactaaaaat gattatgaag ggcaaaaaag tatatgtcct agatgaagga
    35341 attgaataca aaaaatataa ggatactgca ccaaaagcat tatataagaa atttatgtca
    35401 tttgaagatg aaatatgtaa atttggtgta gaaattataa aagacttaaa tgttataact
    35461 aaaaataagt taaatataaa gaaagaacta gaaagtacta gaggttctaa aaaaaaagat
    35521 acaaaagttt tagataaaga tgttttaaat ttaaccagtg tagaaagtgt aaaaatagat
    35581 aatgaattta gtttagattt aaggaataaa aaacttatat cggaagctga cttaagaaaa
    35641 ccaactataa atggagttaa aaacatatta gttaataaaa aaagtataat aacaccatta
    35701 gctgtagatt ttatgagaat acaccatctc aaactaaaga aactgtaagg aggtaatttt
    35761 atggatatag gaaaagttgt aggtaatgtt tgggctacaa gaaaagatga aaaattatgt
    35821 ggccaaaaac ttttagttgt aaaaatttta aaaactaaag acacatacaa ggaaggcttc
    35881 atggttgcag ccgataatgc aggagcagga aatggagact tagttcttat atccaaaggt
    35941 tcctcagcta gagagtcgat tgaaaaatct catgttccag tagatgcaac tatagttgga
    36001 gtagtcgatt catttgaggt gtttgatgaa taaaagtata ggagccatag agtttaaaag
    36061 cattgctaaa ggtatagaag tatccaatga aatgataaag aaatcttcag ttgatgtatt
    36121 gtacttaaaa agtatttgcc caggtaaatt tctaataata gtaggtggag aaacttctta
    36181 tataaatgaa tgtgtagatt atggaataaa acttggagaa ggatatattg tagataactt
    36241 tgtaataaat gcaatttcac aagaaatatt agatggattt aaaaataagt atcaaaagct
    36301 agatagtata gtctctatag gcgttgttga aagtagtaaa gtatgcgctg gaataaaaat
    36361 gcttgataag actttaaaat ccggtgactt agtattagta aaacttcaat tatcttttgc
    36421 tataggtggc aaattagtat atatagtagc aggagattta agtagtttag aatatgcatt
    36481 aaaagaaagt gaaaatgtag taagagaaaa agaagtaata tataagactg taataccatc
    36541 agtagacagt caaataataa aaagtctaat aaaataatgg ggggaattat gagtataaac
    36601 gaaattataa tctatgtaat ggtagtcttc atggtacttg gagctataga taaatgtata
    36661 ggtaacaaat ttggtcttgg agaacaattt gaagaaggta taatggcaat ggggtcactt
    36721 gcagttgcaa tggttggtgt tatatgttta gcaccagttc ttgctgatgt attaagacca
    36781 attgtagtac cagtatttaa tatacttgga gctgacccag ctatgtttgc tggaagttta
    36841 ttagctaatg atatgggtgg tgcgccactt gcacttgaac ttgcgaaaga ccctaatgct
    36901 gggttatttg gtggattaat agtaggtgct atgatgggac ctacaatagt atttataata
    36961 ccagttgcgc ttggaataat tgaaaaagaa gaccaaaaat tcttagcaac aggaatactt
    37021 gcaggtataa taacaatacc tattggagca ttcgttggtg gattagttgc aggattcgag
    37081 gtaatgatgg ttcttagaaa cttagtgcca ataataatat ttgcagtagt tatagcactt
    37141 ggattattaa aattcgaaaa tgctatgata aaaggattca catactttgg aaaaggtgta
    37201 gtaatagtta taactttagg acttgctgct gccatagttg aagctttaac aggaatagtt
    37261 gtaatacctg gaatgaaacc aatcagtgaa ggtatagaaa tagttggaga tatagcaata
    37321 gttttagcag gagcattccc attagtgttt gttataacaa aggtatttaa taaaccatta
    37381 atggctttag gaaaagttct tggaatgaat gatgtatcag cagcaggcct tgttgcaagt
    37441 ttagctaact gtataccaat gtttggtatg atgaaagata tggacaatag gggaaaaata
    37501 ataaatgtag cattctctgt atcagcagca ttcgtatttg gagaccactt aggatttacg
    37561 gcaggattta attctaatat gataacacca atgatagttg ctaaattagt tggtggtata
    37621 acagcagtat tgttagctat ggttatcgca aataagacac taaagaagga gaatgtataa
    37681 gatggatata tcaaatatag ataaaaattt aattgaaaca ttagtaagac aaataataga
    37741 agaaaaaata agtggaacta aagacacagt agattttgtt agaaataaag acattagtgg
    37801 aataacttct ataaagttac caactgtaaa agttagtgaa tctgatagat tagatacagg
    37861 gaatccaagt gatgtagttt acacaaaaga tttatttaca ttagaggaaa gcccaagatt
    37921 aggttgtggt atgatggaaa tgaaagaaac aacttttgat tggactctaa actatgatga
    37981 aatagattat gtaatagatg gaactttaga tataataata gatggaagaa aggtttctgc
    38041 ttcttcaggt gaattaatat tcataccaaa aggaagtaag atacaatttt ctgtacctga
    38101 ttatgctaga tttatatatg taacatatcc ggcagattgg gcatctcaaa attaataaaa
    38161 atcaagttaa gttaataata atcaaataaa taatttaaaa tacaaactct taaataagca
    38221 cacatattta aaaaagctat gaattaaaat tcatagcttt ttttataaat aatgttatat
    38281 tttagacgta ttttttctat atttactggg agacatatta tattttttat taaataatct
    38341 aataaaatgc tctacatttg gataaccaat actattttac tgataatctt ttccttatca
    38401 ctaatcttac attttaaaat attattttta ctcgtaatat tatcataaga atttgtttct
    38461 tatttaaaac taattagaat tataaagttt attgccatgt tattaataaa ataaatccag
    38521 ttaaatcgag tgctagttaa agtaataaga aacttttaca atggtttcct ttatcgattg
    38581 aaataaaagt taatatggta taatatctaa agagagaatc ttatcaatta gaatatgcat
    38641 agaagcaagt ggcttaaaag gagacgttat atggaagaga tagtaaagaa agaacaagca
    38701 agtatgaatg atattttttt gtatcttaaa gctaaatcaa actcattata taaatttgta
    38761 atattatata atgagtttat caataaacct aaagattatg gaactgggga acttataaac
    38821 atggttgaag tacatatgct aacagcgatt gaagaaaatc caggaataag tccaactcag
    38881 ttagctaaaa tatggaacag aactaaaggt gcaatatctc aaactatatc taaattggag
    38941 aaaaagggtt atataactaa agaaaagaaa gaaggaaatg caaaaactat attactatat
    39001 ccaaccacat caggagtaga gttaagtaag gcacataaac tatatgacac catagatgtt
    39061 acaagaacat ttgaatactt aatcaaggag tgtacattag aggagataga tagtttttat
    39121 aaagtaattg atttgtttat taatttatta gaagaatctc cgcaggaaaa taatgattct
    39181 gaaaaagtgt agctaagatt gaagttgaat aaagagaaat agatattata gaagtagtac
    39241 ttaagtacac attatataaa aatataatag gtatatgatt aaaaagttta gtggtttaaa
    39301 gtttaaccac taaacttttt taatgtctat aatctactat tatttaattt actaaaaata
    39361 aaagaactca ttatattaag ataaaaatag aaaaataaat agaaaaatac tataatatat
    39421 cagcttaata cagaaaaaag ttaaaaaatt tgagaaaaat aaaaatgaaa acgttttata
    39481 ttgacataga gaaaaagtag tgataccatt taaatatagt ttagtagcta aactatattt
    39541 aaattataat aactatttta gggggatgtt atgaatttaa aacaattaag tgaaaaatac
    39601 gaagaatatg taattcaaat gagaagagaa tttcataagt atccagaatt atcttttaaa
    39661 gaaataagaa caacccaaag aataagggaa gaattacaaa aaataggggt cccttttgta
    39721 tctattgaac caaatatcgt aatagctact atacaaggca aaaatgaagg taagacaatt
    39781 gcaattagag gagatataga tgcgcttcca atgcaagaag attcagatgt tgaatacaaa
    39841 tcagaatatg atggaataat gcattcttgt ggacatgatg ctcatggagc tatgttacta
    39901 ggacttgcac atatgctaaa tgatataaga aaagatttaa aaggtagagt attattaatt
    39961 tttcaagcag ctgaagaagt tggtggcgga cacaaggaga taatacagta ctttaaggaa
    40021 aatggaggac cagatagatt aatagctact catgtttggt ccgatattga agctggtaaa
    40081 atttctgttg aaccaggacc tcgtatggct ggtgggtctg gttggagaat agacataaca
    40141 ggtagaggag gtcatggttc tagaccagat caaagcatag atcctataaa gccagcttgt
    40201 gatatagttt taaaagtatc ttctatacca gttaatcata taagtgtact agaacaatgt
    40261 gttgtacatg catgtgcaat acatggagga actacaatag gaaatgttat tccaaacaat
    40321 gcagaggtaa taggtggata tagatatttt actgaagaat caggcaaaaa agtgtttgac
    40381 attataaagc aaatgagtaa tggtgttgga caagtttatg gagtggatgt gaaggttact
    40441 catactggag gcataggacc tgttatcaat gatgaagaag cagttaagat ggctaaagaa
    40501 atagtttcta atatagatgg attggagtta gattcttatg agccaatatg tgcatcagat
    40561 tgttatggtg aaatattaaa agagtattct ggtttttatt gttatctagg ggtaggtaac
    40621 aaagaaaaag gaataatata tgcacaacac catcctaagt acaatataga tgaagataca
    40681 ttaaagttag gttgcgaatt tatggctaaa tatgcagttg aatttttaaa taaaaataat
    40741 aactaaaata aatcgaattt tataaatggg gggatgaaaa tgcaaggtgc attaaaggaa
    40801 aataagaaaa aaagcggtgg aggattttta ggatggattg aaagagttgg gaataaaatg
    40861 ccacatcctc tagcattatt tacatatatt acattgatag tagtagcatt atctgcaata
    40921 gcaagctttt taggtttttc agcaacaagt cctgctacag gaaagttaat aaaagttatg
    40981 aacttaataa gtgcaaaagg tttagtacta tttatgcaag agtttgttaa gaacttccaa
    41041 aacttccctg tgcttggagt agttttagtt atggcagttg ccacaggagt ttgtgaaaag
    41101 acaggatttt tttcaactgc cataaaaatg agtttatcaa aagttaaggg gaatgcggtt
    41161 gtatttataa tagcttttat aggagtattt gctaatcaag ctggtgatgc tgcttttgta
    41221 ttagtaccaa ctcttgcagg agcaatattt tatggattaa atagaaatcc attagctggt
    41281 atattctgtg gatttgcatc agttggtggt ggatttgcaa cagctgtaat tcctggggga
    41341 tgggacgtta cgctaacgcc aataactgta tcagctgctc aaactattca acctgcattt
    41401 gatatgacat tattagctag ttattatgca ctatttgtat ctgcgtttat agtagctaca
    41461 gtatcaacaa tagtaacggt taaatttata gaacctaaat taggtaagta tactggtaaa
    41521 ccagaaggta tagatgataa tcaaggtttt gaggtcacaa aagaacaagc aaaagcagca
    41581 aagttagcag gttttacagt tttagcttat gtagcgttat taattgcttt gtgtatacca
    41641 gctaatagtt ttttaagaag tccagaaggt tctttaatat ttggagcacc acttatgtct
    41701 tgcttacagt tttttatagt aatactattc ttcttgccag ggattgtgta tggaatgagg
    41761 gttggtaaaa tcaagactgt aaaagactta aatgatatat tatgtcaatc aatggcagca
    41821 atggcaccgt ttatcgtact tgcaatagtt ataggtcaat tcttaacgct attctcagtg
    41881 tctaatttag cacaggtact agctataaaa ggtggagcat tactcaactc attgccacta
    41941 ccaccacaag ctataatact gctattctta gtactagtag cgtttataaa tatatttgtt
    42001 ataagcggaa gtacaaaatg gatgatattt ggaccagtat ttgttccaat gttaatgcaa
    42061 ttaaacatac atccagcatt tactcagttt gtatatagat taggagattc tgtaaccaat
    42121 catttatcac cattaaatgc attctttata atacttttag caacagtcca aaaatacgat
    42181 aaaaatgcag gtatgggaac tatattctca gctatgatac cttacactat aggttacttt
    42241 gtagtacttg cagttttagt agtagtttgg atgacaatag gtataccagt aggaataggt
    42301 ggacaagttt ggttataaaa catatttaat aattttggga ggaaagaaaa tggaaacaac
    42361 tgaaataaga tacaattttg atgaagtaat agatagaagt ggaacaaact gtcttaaata
    42421 tgatcttaag agtcaattta tgccagaatc tccagaagat gcactaccac tatgggtagc
    42481 agatatggat tttgcatgtg cccctgagat aattaatgca atgcatgaaa gaatagacag
    42541 aaaaatattt ggatatagct ctcaacaaac tgatgattat tatgaagctg tatgtggatg
    42601 gtttaagaga agatttgatt ggaaaataga aaaagagaat atattcttta gcccaggggt
    42661 tgtgcctgcg ttaggatttt tcacacaaat attaacacaa aagggtgatg gtatcataat
    42721 agaaaagcct gtatactatc cttttgaaga taaaataact aacaatgaaa gaaaagtagt
    42781 taatagtcct ttaaagtttg aagatggtca ttattctatg gattatgatg gatttgaaga
    42841 attagctaaa aatgaaaata ataaggtgtt tatattatgt agtcctcata atccagttgg
    42901 tagagtatgg aaaaaagaag agcttagaaa aatagtagac atatgtaaga aatatgattt
    42961 gtggataata tctgatgaaa tacattgtga tattattcgt aaaggtgaaa agcatatacc
    43021 attagaagta gcatgtcctg attataaaga tagaataata acttgtacag ctccaagtaa
    43081 gagttttaac ttagctggta tgcaattatc aaatatagta atcaataata aggaattaca
    43141 agaaaaatgg atgcttgaaa cagattctaa attagctata ttcctaccta atccattcgc
    43201 aatagttgct actaaagttg cttataatga ttgtgaagat tggatgaatc aagtaaatga
    43261 gtatatagat ggtaatatta aatatgtaga agattttgtt aatgagtata tgcctaaagt
    43321 aaagataata aaatctcaag gaacttactt agtttggtta gactttagag ggtatggatt
    43381 agatgcaaaa cagcttgaat atgtaatgct taacaaggcg aaggtattgc tagatgaagg
    43441 atacatattc ggagaagaag gagcaggatt tgaaagaata aatgttgctt cacctagaac
    43501 aattatagaa gagtgtatga atagaataaa atgtgcattt gaaggattat aatagtaata
    43561 tctaaataat atatttgtgt attttaaaaa aagactatgc taaaaaaata tttcaaagca
    43621 tagtctttta aagttttatg atgagtttaa aaaatttcaa aacgttacta ttcacttata
    43681 tgtttatatt agaaataatt ccacaatata ctcattttct aaagttgcac ttttatatac
    43741 cttgcttcac caatatcatg tgtaaccaaa atagtagact tattctcatt cttaataata
    43801 ctataaacat catcacaaac taataatcta gtctgataat caagagctga aaaaggttca
    43861 tctaaaagta gaatatctgg atttacagaa agtgttctaa taagcgcaac tctttgtctc
    43921 atacctccag ataattcttt tggatacata cttctaaaat cccataatcc ataagtcttt
    43981 aaaaggcttt caactctatc taaagatttt ttatcttttt tgccttgaat ttccaatcca
    44041 atagttatat tatccattat atttctccat tcaagcaaat tatctttttg aaacatatat
    44101 ccaatatttc cagtaatctt tatatcacca ctagtcggtt ttaaaagatt agtaagaata
    44161 tttaatattg tagatttacc acttccagaa ggaccaagca aagttaatat ttctccttct
    44221 ttcaagttaa aattgacatc ctttaatact tcaagctcgc cttccttagt gtagaagttc
    44281 atatttatat ttttaacttc tactatgttg tcattcatta tgccaccccc tataactttt
    44341 agctcgtata tattatgtta ttaacaatat gacctatttg taccattttt cataaatata
    44401 atataaatat tttgtttatt tacgtatttt cttagtaact tgtacgtata aattatagat
    44461 aaataaatta taaggtaggg gataaatttg agtaacataa taacgaattt aatagagtca
    44521 atatttacta atccaataac tatattgttt ttacttgcaa taactgtgta ttctgttttt
    44581 aaaataatag aaaataacag agtatattca tttgtaagtt caaaattaga cgaaatcaat
    44641 agagactata agacaagtga gttttataaa aaggtaaggg atgactacta tacatatagt
    44701 aaagaaaatc cttatgcaga cgtaaatata acttcattta tagaggaagt tgtatctgat
    44761 ttaaagcata ataatttgcc attgttagaa aaaattagaa gtataaaaaa ttcatcttca
    44821 ataagtatat tacttggggt tttaggtacg tttgttggtc tttctacaat gcttttatgt
    44881 gttgatacta aagacattat aaattcactt ccttcaacta ttagtagtat gcaaactgca
    44941 tttacaacta gtatatttgg agttgtattt tctctaatta taggttactt tactaagata
    45001 aaagattgtg aacatgtttt gatacaaata atgttaaaat ctgaaaattt actaacatct
    45061 gaaataactc attttaagtc agaaagaatg gatttaaaag tagaagaggt aaaaaataca
    45121 ataaaacaaa taagtaagtc tatagaagct attgaaaaat ttgataaaat atctaaagat
    45181 ttaaatgact ttaatgatga atttatcagt ggtatagaag ctttaaaaag ccttttagaa
    45241 ggttctcaaa gttctattaa gacatttgac cagagcgtaa gaaaattaga taaaca
//
LOCUS       DAFAZV010000029        45116 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFAZV010000029 DAFAZV010000000
VERSION     DAFAZV010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 45116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45116
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.029"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            24..836
                     /locus_tag="KOU88_002358"
     CDS             24..836
                     /locus_tag="KOU88_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK3212231.1"
                     /translation="MYLERPELYKQSEINFWDDEYISKQLLKAHLDTNFEGASRNFNF
                     IEDSVNWIVTVANPANYPKLLDLGCGPGLYAEKFAQKGYKVTGIDFSKRSINYAQNRN
                     KETNLNINYLFQSYLNMNYNEEFDLATLIYCDYGALSTENRRLLMEKIYDSLKPGGKL
                     ILDVFTINKYNNFEEIKYWEINEDGGFWSNEKYMCLQDNCKYNDYNTLEQTLVITEKD
                     ENVFYVWNHYFSKESFLLEVENIGFKSVEFFSNVKGEAYSDDSMTMGLVLQK"
     gene            1884..2645
                     /locus_tag="KOU88_002359"
     CDS             1884..2645
                     /locus_tag="KOU88_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896901.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBK3212232.1"
                     /translation="MIGIYFSGTGNSRYCVEKFLQEYDITANSYSIEDNELLQHINNH
                     ENIIFSYPVQYSNVPKILKDFIINHSTLWNGKRVFIIATMALFSGDGSGVLSRILKKY
                     GAITVGGLHVKMPDSIGDEKVLKHSLEYNRKLVIKAEKKVTKAAKKLKHGSPPKEGLG
                     FLSHIVGLFGQRLYFINKTNMYTDKLKINTEECIVCGKCVNLCPMKNLVIKNCMIVAN
                     GQCTMCYRCVNNCAKKAITLLGKKVVEQSNIKKYM"
     gene            2710..3492
                     /locus_tag="KOU88_002360"
     CDS             2710..3492
                     /locus_tag="KOU88_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBK3212233.1"
                     /translation="MEYYIVDSFATKLFKGNPAGVCVLDRRIPLELMQKIAEENNLPE
                     TAFVVKCKGNYELRWFTPKAEIDLCGHATLAAAYVISNFIDVNVKKIDFFTQSGKLEV
                     TRNGNLYEMIFPEIMPIEIELSPQQANLIGCVPSAVYSSRDLILLLNSEQEVINYKPN
                     YAQLRKLTDWLGIIITAQGSNTDFVSRYFCPELDSEDPVTGSSHCNLIPYWSEKLGKH
                     KMVAAQLSNRGGIIQCEVLKDNTVKISGEAVLFMQGTIKIDI"
     gene            3759..4178
                     /locus_tag="KOU88_002361"
     CDS             3759..4178
                     /locus_tag="KOU88_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBK3212234.1"
                     /translation="MDKISGKLTVLFEEPFWVGIFERQDGKKYEACRVVFGAEPKEVE
                     VYEFILERFFSLDFGSIKLEKNVTKDNIGYKRMQRKVKKEQEKETIGTKAQNALKLQY
                     EERKQDRKNLAKNKKEEEKERLFNLKQEKRKAKHKGH"
     gene            complement(4281..4547)
                     /locus_tag="KOU88_002362"
     CDS             complement(4281..4547)
                     /locus_tag="KOU88_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBK3212235.1"
                     /translation="MKNFILIYFIVINSIAFFSMYIDKKRAIRNEWRIKEATLMSIAV
                     IGGSIGSIIGMYSFRHKTKHIKFTFGIPFILFLQFLLVYFYILK"
     gene            4774..5475
                     /locus_tag="KOU88_002363"
     CDS             4774..5475
                     /locus_tag="KOU88_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212236.1"
                     /translation="MKFIVEKEVFDKLENVCFGVVVAKGIDNTKEIERISNLLDISID
                     RVEDYFKDKKVKESEEIIPYREAFRSLGMNPNKFMSSIEAMTTRVAKNKKLPHINPIV
                     DLGNSISLKYLLPMGAHDMDFRNDDVYVRFSKKGDKFVPFGETDVELMEEGELIYSVG
                     DMVKTRRWIWRQGEEGKITNSSKNIFFPIDGFTDANLDKVMSAREELAKLLKEIFNCE
                     IKVGFVDKDNPEMEI"
     gene            5557..6165
                     /locus_tag="KOU88_002364"
     CDS             5557..6165
                     /locus_tag="KOU88_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK3212237.1"
                     /translation="MKKTIIKNVNPMIENKFIGLFEIEYKNKLDEDKVWMVASRKSSE
                     QLKNIYLKNEEDSVDAVVIVGLHKSSKKLILIRQFRVPINGYIYELPAGLVDEGESID
                     ISVERELREETGLTLLEIKKNKSIDKVYLSPGMSDESVAFVYCICDGDITDEFLEPDE
                     EIEALLISQEDAKEILQSNHKIDTKAFLILQMFVSLGAKLFE"
     gene            6489..6953
                     /locus_tag="KOU88_002365"
     CDS             6489..6953
                     /locus_tag="KOU88_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4624 family lipoprotein"
                     /protein_id="HBK3212238.1"
                     /translation="MKKLVIILISIISVVSLTACKKSNESKYNNLNNKESGQTTIEMD
                     LDKNYDTSDPFVNARLFCVSNDIDVLDTEISFKMDGDSGIVEIKDNKTDETLWSNIWH
                     GSVDNDTFAISLSNIQKEKEYAICFTGIKINHAVVKVTFESNLVKEKEKPSK"
     gene            7590..8606
                     /gene="gap"
                     /locus_tag="KOU88_002366"
     CDS             7590..8606
                     /gene="gap"
                     /locus_tag="KOU88_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011948756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBK3212239.1"
                     /translation="MKIKVGMNGFGRIGRAVLRIAQEELGDNIEIVAINARATTESLA
                     HLFTYDSCYGTFRGEVEAKDEDTLVVNSKEIKILRYNDPEELPWKELGVDIVIESTGL
                     FTQREKAEKHIKAGAKKVIITAPGKNEDITIVIGVNEKEYDNEKHNIISNASCTTNCL
                     APFAKVLDEKFGIVKGLMTTVHSYTNDQRILDKSHKDLRRARAAAESIIPTTTGAAKA
                     VSRVLPQLEGKLNGFSLRVPTPTVSLVDLVCELKENVTSEQVNSVLKDAAEGELKGVL
                     GYCDKPLVSIDYKGDSRSSIIDALSTMVIEDNMVKVVSWYDNEWGYSSRTVDLVKYVA
                     EKLK"
     gene            9001..10170
                     /locus_tag="KOU88_002367"
     CDS             9001..10170
                     /locus_tag="KOU88_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212240.1"
                     /translation="MEKLTDRRQVKAVSMETFIFLILLVVGFGYVGSIMGAGMMFKVI
                     MSTAHALLLETVFLIMAMAVLAGALSALLSEFGVIALINKIFAVFMKPLYGLPGASIA
                     GAITTYLSDNPAIIPFAKDKTFTQYFKQYQVPALCNLGTAFGMGLILTTFMISQGTEY
                     VLPALIGNLGAIIGSVISVRIMLTFTKKFYKYNPEEDKATGTLEKKDEFREIREGNVF
                     QRALDAILEGGKMGVDMGMAIIPGVLVVCTLVMLLTFGPSTDPVTGQEVYTGAAYEGI
                     KLLPVIGDKLGFILEPLFGFTSPEAIAFPITSLGAVGAAMSLVPEFIKSGAITPNDIA
                     VFTAMGMCWSGYLSTHIGMMDALNARQLAGKAILSHTIGGLCAGAAAHFIFTLVG"
     gene            10550..14803
                     /locus_tag="KOU88_002368"
     CDS             10550..14803
                     /locus_tag="KOU88_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBK3212241.1"
                     /translation="MDELFHIGIDVGSTTVKVVVLNNSNNIVHKEYRRHYSDVKKSVK
                     EVLNGIYEKLGDINTTIIITGSGGIGISKKLGVKFVQEVISSTKSIEYFHPETDVVIE
                     LGGEDAKITYLSGGIDQRMNGICAGGTGAFIDQMASLLKTDASGLNELAKGYNVIYPI
                     ASRCGVFAKTDIQPLINDGANQTDIAMSIFNAVVVQTVSVLSCGRKIEGNVAFLGGPL
                     YFLSELREAFKRVLDLKDENIIFPENAQLYIAIGAGLLSVDEDNIQLKSLIEKLDSIK
                     NIEDGEVNLLEPLFKDKNEYEEFSRRHEKEKINYVDINSIKSNCYLGIDAGSTTTKAA
                     LIDEDGRLVYSYYNSNEGNPLKTTIKVINEVYDILPKNIKILSSTVTGYGEGLIKKAL
                     KIDNGEIETIAHYKAAKFFNKDVDFILDIGGQDMKCLKIKDGVIDNIILNEACSSGCG
                     SFLETFASSLSMTIEEFAHEGIYSQNPVDLGSRCTVFMNSRVKQAQKEGASVGDISAG
                     LSYSVIKNALFKVIKIRDLNEIGNNIVVQGGTFYNDLVLRSFEKLIGKNVIRPNISGI
                     MGAFGSALIAKEKYESGYKTSLLSKEELNNIKLEASVTRCKGCSNHCLLTINKFSDNE
                     IFISGNRCEKGEAIYGDKKIGLEKKKPINLFKYKYNRIFRYKPLEKEEAKNGEIGIPR
                     VLNMYEDYPFWFTFFNAMGFRVVLSDRSSKQLYETGITSIASETVCYPGKLVHGHIEN
                     LIAKGIKNIFYPSVTNENKEDSNADNYYNCPVVISYSEVIKNNVENIRNKNINYINPF
                     ISLNDKEKLKKRLYDELSRHFSDIKITKEEVNHAVDKATDEQNLFKMEIQAAGERALK
                     EIKERNMKGIVLCGRPYHIDPEINHGMPELINSLDMAVLTEDSICHLANVQRPLRVVD
                     QWVYHSRLYKAASFVRDKNYLELVQLNSFGCGLDAVTTDQVQEILNEKSKIYTIIKID
                     EGNNLGAAKIRMRSLKAAMFERESKNIDVKNIKVNRIQYAKNNQITNKHTILAPQMSP
                     IHFQFLEKAVNLSGYNIEILKDTDSSVIEEGLRYVNNDACYPAIIVVGQLITALKSGK
                     YDLNNTSVTITQTGGGCRATNYIGFLRKAIYDAGFKDVPVIALSVNGIEDSGIMDNIS
                     LKLINRLFMSVVYGDLLMKVLYRVRPYEKVTGSANALYEKWVDICKSSLVKAKISVFT
                     RNIKDIVKEFDNLEILDIKKPKVGLVGEILVKFHPIANNNLVDILEREGAEAVVPDLT
                     NFFLSCAFNTIYKHTHLEGSRKSRMIGEAFIYITGIYQRVYKKALDKSERFYAPANIK
                     NVAKSTEPVVSLGNQTGEGWLLTGEMVELLNEGVENIICMQPFGCLPNHIIGKGSIKE
                     LKRLYKNANIIPIDYDPSASEVNQLNRIKLMLSKAFKNI"
     gene            14952..15446
                     /locus_tag="KOU88_002369"
     CDS             14952..15446
                     /locus_tag="KOU88_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBK3212242.1"
                     /translation="MSLVYDVYKSKLGNLYILSEDGFIVSIYIGDEKFNNLKNECIKK
                     GIDIKRSKEDLKEAISQIDDYFNGKRKVFNLNIRIEGTEFQKSVYREMLKIPYGETLC
                     YSDIARNINNPKSVRAIGQASKSNKIPIIIPCHRVVGKKDIGGYMGNHSDLKEILLNL
                     ERQS"
     gene            15562..15939
                     /locus_tag="KOU88_002370"
     CDS             15562..15939
                     /locus_tag="KOU88_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBK3212243.1"
                     /translation="MCDKVIASKYHEKGFNCAESVIKAYNEEFNTDIPVCLGSGLGSG
                     CGVASLCGAVNASNIIIGYVKGRNHEDESTKAKVYAKDLTTTVRKEYGSELCIDLKKD
                     LVACREIMDFAYDSLKETLKKEL"
     gene            16145..16585
                     /locus_tag="KOU88_002371"
     CDS             16145..16585
                     /locus_tag="KOU88_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SufBD protein"
                     /protein_id="HBK3212244.1"
                     /translation="MKNLNLLINKLYSKNHNEAYKTFLFLENESLKSNITYCFFDSFL
                     EMIDNENSYIRTRGLLLISANAQWDIDNKIEINIDSILSHIVDKKPSVSRMFIKSIPN
                     ITKYKENLINRIKMELSNADISIYNNNMKPLVEKDINDTLSNIS"
     gene            17213..18520
                     /locus_tag="KOU88_002372"
     CDS             17213..18520
                     /locus_tag="KOU88_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212245.1"
                     /translation="MKEIADAITSEYLSYGINEDISIYEGRFCIYLDKKYRCNGKIYY
                     KMTPPISISFKADIGCVEEIDNEDDNLALDYDNAILEVHGYKIISITINTLSEFSVEG
                     YINDDCIKSKNSYVEYVDFNIINLDKIPGKLIKYNDKVYAGRIEFDINDYVVTIDKRY
                     DYRKELKSELKSKSGAIITHIGRIRRKDGRIFRTNNTINLLDRISTALSFMCGRYVGF
                     CLAKGYRSGNEVYRIWNENQISPFRYVPTWSDTLSNYHNMEKYISLMCKKLEDFYYGS
                     AIKSVVDWYIESLGSATMENNIISVQIALETLSYVILVEQNKILTDEAFDCNLASKNI
                     RLLLDTCKIPYGKHELNIFDNIIKNKFDDGVDLVIYLRNSIVHPSRRTHRAVLEVEDI
                     WNIISIGTRYIELVLLFILGYRGEYSNRLVERCYGEVEVVPWN"
     misc_binding    18606..18868
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            18994..19797
                     /locus_tag="KOU88_002373"
     CDS             18994..19797
                     /locus_tag="KOU88_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3212246.1"
                     /translation="MKNILKKVGIFTIMLGLLGGVVGCSKPDNEKDKDASKESKKEVV
                     VGFDNTFVPMGFLDEKGETVGFDVDLAKETFKRLGMEVKFQPIDWSMKETELNDSKTV
                     DVLWNGYSITDERKKIVSYTEPYLQNKQIIVTLSDSKINSKADLKDKEVGTQQGSTAL
                     DAVEKDKDFMNSLKGGAPVLYDTYDKALRDLEIGRTSAVVGDEVLIRYYMGQKGEDKY
                     KVLKDDFGLEDYVVATSKENPELCEKINETLKEMKKDGTFDKIYDKWFK"
     gene            19835..20446
                     /locus_tag="KOU88_002374"
     CDS             19835..20446
                     /locus_tag="KOU88_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK3212247.1"
                     /translation="MLQGLEIVIAMFCITLIVSIPLGIGVAFLRLSKNKLVSGITQCY
                     ILIMRGTPLLLQMIVIFYGLPLLGIVFDRFTAGVVAFFLNYAAYFAEIFRGGIQSIDR
                     GQYEASKVLGFDKFTMYKRVIFPQVFKRILAPISNEVITLVKDTSLVYILGLNDILRI
                     SQIAMNREASLLPLFEAGAIYLIFVAILTKGFELLEKKYSYYR"
     gene            20478..21149
                     /locus_tag="KOU88_002375"
     CDS             20478..21149
                     /locus_tag="KOU88_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK3212248.1"
                     /translation="MLKIKNLNKSFKKNRVLKDISFELEEGQIGVLLGKSGAGKTTIL
                     RCINGLEEFDSGEIIIDNEVIKNKRDMAKIRGKIGMVFQNFNLFPHMTVLENIIESPV
                     NVFKVPRKEAEERARELLRLVDLEDKLNSYPFELSGGQQQRVAIARSCALMPKVLCFD
                     EPTSALDIDTIQRVVNIMNRLKDKGMTILIITHDVVFSNNVADKIISIKDGIVENVQI
                     KEKIV"
     gene            21448..21810
                     /locus_tag="KOU88_002376"
     CDS             21448..21810
                     /locus_tag="KOU88_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBK3212249.1"
                     /translation="MIKLYGYTKCSTVKKAKNWLKENNLEFEDIDMVQNPPSKEELKS
                     IYKTSGYDIKKFFNTSGMKYRELGLKDIVKTESDDKLLEILVSDGMLIKRPLLLDGKN
                     VLLGFKEDVWKSTLLKED"
     gene            22246..22947
                     /locus_tag="KOU88_002377"
     CDS             22246..22947
                     /locus_tag="KOU88_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4253 domain-containing protein"
                     /protein_id="HBK3212250.1"
                     /translation="MSIEDLYDFECVPLNNEIDIDVLFEKMIEDGKEKEYTPIIVIDE
                     KVGLLRKNIDMITKEYGSLENYREYCLTKYNEIDVNQFFDFRKSEISELLKELIDLED
                     DFYDYKHFRPIMNIDIFHEYNKVYIAKIPTIKPYEVFAYIPIGGFNDCPRDEEHIAIA
                     KYWYEKHGIFPIAIGCDTVQYSVKNLTKDGKKFDDLCIELVFYCEDIIIQGYETLKAL
                     KDVLKRSTIVLFWWD"
     gene            23218..24036
                     /gene="larE"
                     /locus_tag="KOU88_002378"
     CDS             23218..24036
                     /gene="larE"
                     /locus_tag="KOU88_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent sacrificial sulfur transferase
                     LarE"
                     /protein_id="HBK3212251.1"
                     /translation="MEVNFVKEKEKLDKLKKMLLELGSVVVAYSGGVDSNFLLKVAKD
                     TLGENVIAVTIHAMMHSSREIEEAKQYTQNFGVKHIILNIENFDLKEFKENGVDRCYH
                     CKKYIFSKIKEVAKEHNIKYIVDGTNIDDLGDYRPGLKALSELGVISPLKDSSLKKEE
                     IRSLSKTLGLNTFNKPSFACLASRIPYGVEITDENLRIVEKSEEYLSNLGFSQFRVRM
                     HGDIARIEVGQEELGKFFENNNFNKVDTKLKIFGFKYVTLDMSGYKMGSMNLNV"
     gene            24091..25239
                     /locus_tag="KOU88_002379"
     CDS             24091..25239
                     /locus_tag="KOU88_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBK3212252.1"
                     /translation="MKNYTLISPCFFGMEKMLAREITNLGYEIIKTEDGRITYKTDEF
                     GIAKSNMWLRCAERVHLKIAEFEAKSFDELFENTKRINWSRYIPYGAQFPISKASSIK
                     SKLYSTPDVQAIVKKAIVESLKKSYLEDGLLKEDKEKYPIFVFIHKDKVTISIDTTGD
                     ALHKRGYREKANKAPIRETLAAGLIYLTPWKAGRVLVDPMCGSGTILIEAAMIGINMA
                     PGLNREFISEKWRILDKKIWWDVRKDAFNKIDNESKFKIYGYDIDEESIDIARENAEI
                     AGVDEYIEFNVGDATQFKSEDEFGFIITNPPYGERLEDKDSVKQLYKELGYAFRKLKN
                     WSYYLITSYEDFEYEFGQKADKKRKLYNGMLKTNFFQYPGPKPPRNNK"
     gene            25375..26763
                     /locus_tag="KOU88_002380"
     CDS             25375..26763
                     /locus_tag="KOU88_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212253.1"
                     /translation="MKVLKLITVVALMMLFVTGCNIKTESPEQLAKIPDYDDTKKVLY
                     DGIDQLLKPDSSMILPSNTKEVGKINKVDLNSDGIDELVVFEQKEDLSNNVSQVGFVT
                     LSYNGEKYVLGDHFLENGESIEYANFYDLDSDGYKEVILLVKSKDKTNMHIYKVVDNE
                     ITKIYDLDASWLQNKEDFNDMKVKIGYIDGDDKLDILMLHLNNKTNEMFASVANFDGK
                     MKIKDSVKFENVKNLSELYITLGNVASSIGNSSAAIKGIVLDIPILKDNNYITQILYM
                     KDGKINKAFSDYDKTITKSYYIPVDDIDKDKIIEIPIVAGSTGNNKNTYSSKSSATIS
                     WYRWNGKEGADSSLIFTSQIYYNYKYNFKLFIPNNLFDKILVEQEFVGEKAVFKFYYF
                     DYSDRKNLFNIVVESKNKLEDRKNTGTQNSIVLQESDEYTFLLVVNNANEMDKLDMTI
                     DALKEYFSLIYG"
     gene            26792..27490
                     /locus_tag="KOU88_002381"
     CDS             26792..27490
                     /locus_tag="KOU88_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3212254.1"
                     /translation="MKEKILILEDEIGIRSFVSINLKREGYEIVEAGTGREAIEKMTT
                     EKDITIALLDVMLPDISGIEVCKFIRENFDQVGIIMLTAKAQEDDKIEGFISGADDYI
                     IKPFSIKELLVRVSALLRRVAKDDSSVKSSEIVSPPFILDIDKRKLFKNGKEIELTPT
                     EFSIVKYLISNAKQSLSRDQILDEVWGTNYLYDFKIVDVNIRRIRNKIEDDPSKPKYI
                     QTIWGYGYCFRKEE"
     gene            27493..28926
                     /locus_tag="KOU88_002382"
     CDS             27493..28926
                     /locus_tag="KOU88_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3212255.1"
                     /translation="MLHFEGLRKKVIKNYFIIIIIMVTLFEGLFMFYIQNYYYDSVKQ
                     LLESEIKYADEYNAITMETTSFEKKVKNIFDKQPLTKNSEFGISIIDKDKNIILDQYG
                     FKSKEKANYEDVNNALKDIKTKNLTPYTYRIPDTGEHVMSISLPLKVNNIIEGVVRYT
                     VSLDAIDNAILKQATWLILAGIFILIIAILISLKFAETLIKPLRELKKFANELAVGNY
                     NIKLEKMKIVDDEIGDLAQTFEHMAHEIDKSEKLKEEFISSVSHELRTPLTSIKGWSE
                     TLGYESITREELDLGLGIIQDETERLIKLVEELLDFSRLSSDRIKLHVDIVDVEGLIV
                     GVVNQLKVKAAEKDISLLFEFENEFIENIQGDKNRLRQVLINLIQNSFKFTSQGGYIK
                     VVASQDEEITTISVEDNGSGIEKQNLNKVLDKFFQEDYNKAGSGLGLAISNEIVKLHG
                     GRMKIESEKNVGTKITFNIKNKFAKQA"
     gene            28948..29685
                     /gene="truA"
                     /locus_tag="KOU88_002383"
     CDS             28948..29685
                     /gene="truA"
                     /locus_tag="KOU88_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011010156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBK3212256.1"
                     /translation="MRNIKMIVAYDGSRYKGYQKLGDNNMTIQEKLENVLSKMTNETV
                     EIIGSGRTDMGAHARGQVVNFRTNCMDSLDKIQKYLYEYLPEDIVVKTVEEVDERFHS
                     RYNVKSKTYMYKIDNNKYHNPFIRKYATHVSKKLDLDRMRKASEYLVGEHDFTSFASS
                     KSKKKSNVREIYSINIKEDDNVIEIYVEGNGFLYNMVRIIVGALIDVGLKRRAPQDIK
                     YMLESKDRCQSSDTAPAKGLCLWKVTY"
     misc_binding    29796..30003
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            30256..31455
                     /locus_tag="KOU88_002384"
     CDS             30256..31455
                     /locus_tag="KOU88_002384"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBK3212257.1"
                     /translation="MKEKVVLAYSGGLDTSIIIPWLKENYEDIDVIAVCGNVGQEDKM
                     EDVYEKALQSGASKAYVDDISEEFVTETIFKAVKAEAKYEGKYLLGTSLARPIIAKKL
                     VEVAHKEGAKYICHGCTGKGNDQVRFEATIAALDPTIKVIAPWRIWDIKSREDAIDYA
                     EKHNIKVTATKAKIYSVDANLWHVSTEGGDIEHLENEHKKDVYKQCVDPEDACDVAEY
                     VEVYFEKGVPKKVNGEELSPVALIHKLNELGCKHGIGVIDIVENRLVGMKSRGIYETP
                     GGTILYEAHNILESATLDKDTLHFKQMVSYKYGELIYNGLWYCKLRESIDAFMEQTQD
                     NVTGTVKVKLYKGNIKPAGIFTENALYDEGISSFGNSELYDHKDAEGFINLFTLPLKI
                     RAMKAGK"
     gene            31702..32748
                     /locus_tag="KOU88_002385"
     CDS             31702..32748
                     /locus_tag="KOU88_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4872 domain-containing protein"
                     /protein_id="HBK3212258.1"
                     /translation="MRKIIEIKHHSHDYECMWNGIEDLYINKTGECLPNDFFFLLSGF
                     GSFCYMKTNKADLKRMVALGDGRTKQMYKFLAPIVGFEYKHHEFKKYEQALKKAKSEI
                     DDGYPVILGALDMYYLPYYKKLYHKEHIPFHYILMVGYDDEGIYLYDCGRTELLHLSY
                     DKLRESMNCNSPGLSKENTICTIRMNTSKNKYNIAREAIAIKRDMFLNPPKGFLGYKG
                     FEKFIKELPQWNTELDKDDYDKILTNMVMFFGTVPTIPNAIKGIKEPDTVQFKGGFDK
                     MSRMLNSIGEEYKNDSFIQVADIFDKTAIIIEKISNIIIDYLTQTCDDTEQLPLLFSE
                     VLEHMKTGYLILDV"
     gene            32856..34019
                     /locus_tag="KOU88_002386"
     CDS             32856..34019
                     /locus_tag="KOU88_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3212259.1"
                     /translation="MRTVKQVSDLTGISVRALHYYDEIGLLKPNKITDAGYRLYDDES
                     IKTLQQILFFKEIDIPLREVKEIMSSQYFDKVEALKNQKKLLILKRKRLDELIELINQ
                     TLRGEGNIDFKEFDMSEYFDVLEEFKREHRNKVIKIYGSVEKYNEYIERVKSNEEKIA
                     KMAIKQYGTIEKFAKAIKTNFSSDILNLGEKFDRYKNDCLKEKHPKLKELYRKLVEDL
                     SRNPSSTDLQEIAKEITDISKKDYEIFSMDTGDDNWYYMVQNYLVNPMWIEEVDKKYG
                     SGAGKFIGQVLKTYLRDRKPKINTLYEKLVEDLSRDCSSREVQSIVEEIDNEMKRSNE
                     FYKIDNGERYFDYMSELYLQDSDYIKVTDKNYGDGASKFIGEAFKIYFDNNNC"
     gene            complement(34108..34488)
                     /locus_tag="KOU88_002387"
     CDS             complement(34108..34488)
                     /locus_tag="KOU88_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4363 family protein"
                     /protein_id="HBK3212260.1"
                     /translation="MKSTTFVILWTILFVLFGFYVNNKLYDFTEGYKDNISVLEKSIE
                     NEDWEKAQKEADSISTSWNKEKNHWYKVLNHEYFDEIGLRFNILDKAIYTENKLKSLE
                     EVESIKTYLGNIIESVKFDVNYIF"
     gene            complement(34491..35150)
                     /locus_tag="KOU88_002388"
     CDS             complement(34491..35150)
                     /locus_tag="KOU88_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBK3212261.1"
                     /translation="MTVVLIRSIILYITVLIALRVMGKGEIAEMNCFDLVITLLIAEV
                     ASVPMENNNIPIINGVAAISGLVIMQTLISFLSLKSRKLSSFLSGKPSVLIDKGKIVY
                     KELKKERISIDELLEQLRIQGYFNLKDVQYAILETDGNLSVVPASSYNSTPPRAFNHL
                     PIPLILDGRIINKNLDIAQKDTNWLMGILKSNHIETFKDVLICVLDENDKIFIQNKKG
                     D"
     gene            complement(35256..36230)
                     /locus_tag="KOU88_002389"
     CDS             complement(35256..36230)
                     /locus_tag="KOU88_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease domain-containing protein"
                     /protein_id="HBK3212262.1"
                     /translation="MKYKLFIDFEFNILDDNKNKPKEYNGAELISIGGILVDNEFNTI
                     DNYYSLVKPKYNKILSNKCKNLTKLNQLDINNAPNLLYVMDDFYKWFCKFDDVTIYNW
                     GDFDIAGLLTSFRVYKYTGKCLELFNMMIDIQPFISQHITYNNRILSKQISLLNMKKI
                     FSVKGDIKHNSLSDAVDLMNVCKCFFFNSPKNIDILEELYNKLPALKTPLYYIPYFED
                     ENFELKFDRTPEDIIIYLKQILTILNISKKEIYFKKRSVLVNNSKTINFKNLSSSFKL
                     IKLNEFEEYPDFILKLGDKKSFVESVIKINKSNRKSIKNLILKLSKKP"
     gene            complement(36270..36617)
                     /locus_tag="KOU88_002390"
     CDS             complement(36270..36617)
                     /locus_tag="KOU88_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212263.1"
                     /translation="MLNLKEIREEIIKKYIGDSLISELTEELKNILITDLQSNPFKSN
                     IELSIIPANIEIFKKIENILIDSKVNLKMGWERILINYILKDLFELNYEINKSCNEPL
                     MFRVIISIDSYDA"
     gene            complement(36835..37791)
                     /locus_tag="KOU88_002391"
     CDS             complement(36835..37791)
                     /locus_tag="KOU88_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBK3212264.1"
                     /translation="MKKILITGALGQIGSELTIKLRNEYGEQNVIASSRRVKEGNPVC
                     ESGIFEILDVTDKNRFFEIAKKYDVDTIIHLASLLSAVAESKPLEAWNLNMNGLINGL
                     EIAKELDCKFFTPSSIAAFGENSPKNMTPQDTLQRPNTMYGVTKVSGELLCDYYHSKF
                     GVDTRGVRFPGLISYVTPPGGGTTDYAVDIYYEALKNKRYKSYIAEGTKMDMMYMPDA
                     LQSIVDLIEAPADKLIHRNAFNITAMSFSPEEIADSIKKYIPDFVIEYDVDPVRQSIA
                     DSWPNSLDSSSAVKEWNFKFSYDLDKMTKDMLEKLSEKGIGK"
     gene            38234..38602
                     /locus_tag="KOU88_002392"
     CDS             38234..38602
                     /locus_tag="KOU88_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-GCAxxG-C-C family protein"
                     /protein_id="HBK3212265.1"
                     /translation="MTRPSIYHSQGYTCAEALIKSYNEEHNTDIPISIGSGMGVGMNV
                     GSVCGAVNAAVVIIGYLNGRNSNLDENIARKYSRELLNRVRNKYSSEICVSLKKNKVT
                     CEEIINFTYDALNDMLKNQK"
     gene            39027..39272
                     /locus_tag="KOU88_002393"
     CDS             39027..39272
                     /locus_tag="KOU88_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212266.1"
                     /translation="MFIDEELEGYILTCKISEDFKNIPEYSDEEFYVTVYKDESSDSG
                     YYALLENKEERVVWDGEVVANNIFNNLWIVVNKVKTG"
     gene            39371..39634
                     /locus_tag="KOU88_002394"
     CDS             39371..39634
                     /locus_tag="KOU88_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1883 domain-containing protein"
                     /protein_id="HBK3212267.1"
                     /translation="MEYSYSKMNLKKGDIVEVNLEKQANVILLDHINYVKFKNQRNYD
                     YYGGFAKKNPCRMRVPNTGTWYLVVNQDGNSGIVNFSINTIQN"
     gene            complement(39919..40866)
                     /locus_tag="KOU88_002395"
     CDS             complement(39919..40866)
                     /locus_tag="KOU88_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBK3212268.1"
                     /translation="MSNVTAEQKKEVKGRGFLPSRDGEHFAARIITVNGVINASQAKK
                     IAEAAEKFGNGQLAFTTRLTVELPGVKFEDIEALSEFIASENLITGGTGSRVRPVVAC
                     KGTVCVHGLADTQALAAEIHEEFYKNWYDVKLPHKFKIGVGGCPNNCIKPDLNDLGIV
                     GQRVPDYDSELCVGCKKCAVVEVCPVKAAKLTDKGKLEIDSNLCNNCGKCIESCNFDS
                     IEEKESGYKVYIGGKWGKSVRPGTQIDRLFSKEELMTLIEKAILLFREQGNTGERFGI
                     TIDRIGADKFIEMLLSDEVLERKEEILEALLHLTGGAVC"
     gene            complement(40869..42500)
                     /locus_tag="KOU88_002396"
     CDS             complement(40869..42500)
                     /locus_tag="KOU88_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK3212269.1"
                     /translation="MKVLIIGGVAAGTKTAAKIKREMGDNCSVTILNKGDDISYAGCG
                     LPYYVGKIIEDKSSLIVNTPESFSKLTGAEVRCGVEVTSIDRNAKQVTLKTLSTGEKE
                     NLSYDKLVIATGADPIKPPIPGIDLPGVFFMRTPNDAIKLRDSIENGIKRAVVIGGGF
                     IGLEIAENLSAMGIRVSVVDMAEHVMPGFDTDFAEYVENHMADKGIMIFTGDQVVGIE
                     GENKVEKLRTKNRAIKTDLVVMSVGIRPNTGFLKDTGLEFAPNNTIIADEYMLTNDKD
                     IYVVGDCAFVKNSLTNKPTWSPMGSSANHEGRICAQNISGKSKTYNGVLGTTVVKLPE
                     LNAGKTGLSKEIAEKEGYNVCSVTIATDDKAHYYPGASNFIIRMVAEKNTRKLLGVQV
                     MGPGAVDKIVDIAATAITLGADLYSLESMDLAYAPPFSTAIHPFVVAVNVLQNKLNGE
                     LDSVLLDEIEDFDSWTKLDVSKAPSIPSLRYIPVGEINGEIEGLAKDEKILLICAKGK
                     NSYMAQNRLRRFGYTNTKVLEGGILFYPNLKVMEE"
     gene            42630..43547
                     /locus_tag="KOU88_002397"
     CDS             42630..43547
                     /locus_tag="KOU88_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3212270.1"
                     /translation="MTIRSLEIFVKVAECGKMSEVARNMYITQSSVSQAISEIEKEYG
                     VKLFDRISKKLYLTEAGKKLLGYGRHLLAVNEEMNDCMKHCAKNIRIRVGATVTVGTC
                     VISPIMLELYKVNPLIEPEVFVEDTRLIAKKLLNSELDIAIVEGKIKHPDIVTKSIIN
                     DNLVLICSHKHEFYKRDSIKVSELSNQPLIMRELGSGTRAQLEKQLKELKIPMNIRWS
                     CYNSEAILRAVVDNFGIAVISELLIEDYLKKHLLWACDIEGINLHRTFDIAYHRSKFF
                     TENISAFFDISVEYGKKQARKKSRSVNSL"
     gene            complement(43604..44185)
                     /locus_tag="KOU88_002398"
     CDS             complement(43604..44185)
                     /locus_tag="KOU88_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBK3212271.1"
                     /translation="MGITLAKGQKVSLTKSNPGLKKVIVGLGWDINKYDGGFDFDLDA
                     SAFLTGTDGKVTNDGDFIFYNNLKHASGAVEYMGDNRTGVGDGDDEQINVDLSKIPQN
                     IAKISFSVTINEAITRRQNFGQVENSYIRIYNEETNEELIKYELGEDFSIETAIVVAE
                     LYRHNGEWKFNALGSGFEDGLAGLCKNFGVNIG"
     gene            complement(44225..44791)
                     /locus_tag="KOU88_002399"
     CDS             complement(44225..44791)
                     /locus_tag="KOU88_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBK3212272.1"
                     /translation="MSVSLQKGQRVSLVKDNNPVKNLVVGLGWDMNKLGKKNYDLDAF
                     AIALTNQDKMNVRGDLVYFGNLKHPSKAIIHTGDNLTGKGEGDDEQIIVNLEDIPEYV
                     HKIVFGVSIYKAKKRDQDFGQMNNSFIRLIDSNSKQELFKYNLQEDFSGKVTVLAGEI
                     YRRNEEWKFNALGIGQNEELRELINTYK"
BASE COUNT        17766 a         4849 c         7400 g        15101 t
ORIGIN      
        1 atgttttgtt aaacaaatta tgtatgtatt tagaaagacc agagctttat aaacaaagtg
       61 aaattaattt ttgggatgat gagtatattt caaagcaatt attaaaagca cacttagaca
      121 ctaattttga aggagcaagt agaaatttta actttatcga ggattctgta aattggatag
      181 ttacagttgc aaatccagct aattatccta aattacttga tttaggttgt ggtccaggtt
      241 tatatgcaga gaaatttgca caaaaaggtt ataaggtaac tggaattgat ttctcaaaac
      301 gttctattaa ctatgcacaa aatagaaata aagagactaa tttaaacata aattacttgt
      361 ttcaaagtta tttaaatatg aactataatg aggaatttga tttggctact ttaatttatt
      421 gtgattatgg agctttgtca actgaaaata gaaggttatt aatggaaaaa atttatgata
      481 gtttaaaacc tggaggaaaa ttaatattag atgtatttac aataaataaa tacaataatt
      541 ttgaggaaat taaatattgg gaaataaatg aagatggagg attttggagt aatgaaaaat
      601 atatgtgtct acaagataat tgtaaataca atgattataa tacattagaa caaactcttg
      661 taataaccga aaaagatgaa aatgtatttt atgtttggaa tcactatttt tcaaaagaaa
      721 gtttcttatt agaagttgaa aatattggat ttaagtctgt tgagtttttt agtaatgtta
      781 agggtgaagc atattctgac gatagtatga ctatgggatt agttttacaa aaataataat
      841 ttttttaaaa tgaataaata aaaacttgaa acctttaaca ataaaataac ataataaaag
      901 cttacatatt gaaaaatgga aacttttatg ttatttttag tacattacaa atttgcttat
      961 ataaaaatca atacttgaat tattattttt atgtgaaatt tatctatagt atatttttat
     1021 aaacaagtaa tgttattaaa attaagtata tagttaaaag tgtatagcaa aaaggctgtt
     1081 atattaatgt tagaggttca gggaaaatat ataaagcaaa gtatttacag ataatgtaga
     1141 ttgcacagct ataagttaga taatagaatt atgtaatcaa gaatttacaa caaagtataa
     1201 gataaggata atgctaaatt gccatacagg tgctagatgt gtaaatggat ttaattaata
     1261 ctattgataa agtgcaacaa gcacataaac caattgatga gattattgaa actataagag
     1321 atatagttga cataattaaa atattggaac ctgtttataa ttttaaatca aatcaataat
     1381 gattaagatt aaaataatat taaggcatca atgttataag agtacaatat aaggagtact
     1441 atatagtact ccttacttat acatattagg caataggaaa ttttttcata gttaaatttt
     1501 caagtatttt ttaggaaact ttataattga gaattaaggg tatagtatgt gatgaactta
     1561 ctgaatttat aattaggtta tataatggaa taatcatcaa tagttttact ttagggaaaa
     1621 tatatgctta aggaagtata gcttactaat attattaaaa tgtatattta aaatgataaa
     1681 aaaagaatta gacaagtatt tagtaaattg actatgcaaa attctatcaa gcaggaaccc
     1741 tatgacttta gtcatgggag gttcagtagg taacttgttg aattaagttt atattattta
     1801 aataaactac ttaatttaga taatataaaa agtcagaatt ttaagaatag agctatataa
     1861 tcttagctat taggagaatt actatgatag gaatatattt tagtggaaca ggaaattcaa
     1921 gatactgtgt agaaaaattt ttacaagaat atgatataac agcaaattct tattctattg
     1981 aagataatga acttttacag cacatcaata atcatgagaa tattattttt agttatccgg
     2041 tgcaatatag taatgtgcca aaaatattga aagattttat aataaatcat tcaactttgt
     2101 ggaatggtaa acgtgttttt attattgcaa ctatggctct atttagtgga gatggctctg
     2161 gtgtgttatc tagaatatta aaaaaatacg gtgctataac tgttggtgga ttacatgtga
     2221 agatgccaga tagtatagga gatgaaaagg tattaaaaca ttctttagag tataatagaa
     2281 agcttgtaat aaaagcagaa aagaaagtaa ctaaagctgc taaaaaactg aaacatgggt
     2341 caccaccaaa agaagggtta ggttttttga gtcatattgt agggttattt ggacaacgat
     2401 tgtattttat caacaaaaca aatatgtata cagataaact aaaaattaat actgaggaat
     2461 gtattgtatg tggtaaatgt gttaatttat gtccaatgaa gaatctagta attaaaaatt
     2521 gtatgattgt tgcaaatggg caatgtacaa tgtgttatcg ttgtgtaaat aattgtgcta
     2581 aaaaagcaat tacattgtta ggtaaaaaag ttgttgaaca gagtaatatt aaaaaatata
     2641 tgtaagaaat ttaaagtttt attgaatgta aattgatgta tattttatgt tagaaagaga
     2701 ggttaaataa tggaatacta catagttgat tcatttgcaa ctaaactatt taaaggaaat
     2761 cctgctggag tttgtgttct tgacagaaga atacctttag agttaatgca gaaaatagca
     2821 gaagaaaaca atttaccaga aacagcattt gtagttaaat gtaaaggaaa ttatgaatta
     2881 cgatggttta ctcctaaagc agaaattgat ttatgtggtc atgcaacttt agcagcagct
     2941 tatgtaatat caaattttat tgatgttaat gtaaaaaaga tagatttctt tactcaaagt
     3001 ggaaagcttg aagttacacg aaatggaaat ctatatgaaa tgatatttcc agaaataatg
     3061 cctattgaaa tagagttatc accgcaacaa gctaatttga taggctgtgt accaagtgct
     3121 gtttattctt caagagattt aatcttattg ctaaacagtg aacaagaagt tataaattat
     3181 aaacctaatt acgcacaatt gcgtaaattg acagactggt taggtataat aatcacagca
     3241 caaggaagta atacagattt tgtatcaaga tatttttgtc cagaattaga ttcagaagac
     3301 cctgttactg gttcatcaca ttgtaatctt attccatact ggtctgaaaa gttgggaaaa
     3361 cacaaaatgg tagctgctca actttctaat cgtggtggta taattcagtg tgaagtgttg
     3421 aaggataata ctgtgaaaat ttctggtgaa gcagtcttgt ttatgcaggg aacaataaag
     3481 attgatattt aaataagtat aataactaat ttattatgaa aaataattaa ttttcttagt
     3541 gttaacaata ataaagtaga gttaaaaaac ttgatttcac ttaaatcaat atgatagatg
     3601 ttgatactaa gattgacaag catgattaaa aaagataata tttaatctat aaagataaaa
     3661 acacagtctg gttggtagtc cagacgcagc aatagctgtc agtaacctgc ctccttggtt
     3721 gtccgttctt tagaaagtaa tttaaggagg aactagcaat ggacaaaatt agtggaaaat
     3781 taacagtctt atttgaagaa ccattttggg taggtatatt tgaaagacaa gatggtaaaa
     3841 aatatgaagc atgtagggta gtttttggag cagaacctaa agaagtagaa gtgtatgaat
     3901 ttatacttga aagatttttc tcattagatt ttggtagcat taaattagaa aaaaatgtga
     3961 ccaaagacaa cattggatac aaaagaatgc agagaaaagt aaaaaaggaa caagaaaaag
     4021 aaactatagg gactaaggct caaaatgctc ttaagcttca atatgaagaa agaaaacagg
     4081 atagaaaaaa cctagctaaa aataaaaaag aagaagaaaa agaaagacta tttaatttga
     4141 aacaagaaaa gagaaaagct aaacataagg gtcattaatt ttaattaaat atctttttaa
     4201 taattgctag aaaaaggtgt ataaaatttt taattttata caccttaatt tattgaaaag
     4261 aataaggttt tatatttcaa ttactttaaa atataaaaat atactaataa aaattgtaaa
     4321 aatagtataa atggtatacc aaatgtaaat ttaatgtgtt tagttttatg tctaaaagaa
     4381 tacattccaa ttatagaacc tatactacct ccaattactg ctatagacat aagagtagct
     4441 tcttttattc tccattcgtt tctaattgct cttttcttat ctatgtacat tgaaaagaaa
     4501 gcaatagaat taatcactat aaaatatatt agaataaaat ttttcacagt cttgcctcca
     4561 taaaaatata ttatacatta taaaacaaga tatttgtttt ggaaagttaa atttgtaatt
     4621 agtacatata aaatatttga taagaataaa tataatatta attggaaaat ttaaaaaaat
     4681 taaacaatta gcaaataggg ggtatattta taagacacaa agtgataaaa tctatttaga
     4741 aaataatgta aaataacagg aggataaagc aaaatgaaat ttatagtaga aaaagaagtt
     4801 tttgataaat tagaaaatgt atgctttggt gtagtagttg caaaaggaat agataatact
     4861 aaagaaatag aaagaataag caacctttta gatataagta tagatagagt agaagattac
     4921 ttcaaagata aaaaagtaaa ggaatcagaa gaaattatac catatagaga ggcatttaga
     4981 agtctaggca tgaacccaaa taaatttatg agttcgatag aagcaatgac aacaagggtt
     5041 gctaagaata agaaacttcc tcatataaat cctattgtag atttaggaaa ctctatttct
     5101 ttaaaatatt tacttccaat gggtgctcat gatatggatt ttagaaatga tgatgtatat
     5161 gttagatttt ctaaaaaagg ggataaattt gtaccatttg gagaaactga tgttgaatta
     5221 atggaagaag gagaattaat ttattcagtt ggagacatgg taaaaactag aagatggata
     5281 tggagacaag gagaggaagg aaaaattact aatagctcaa aaaatatatt ttttcctata
     5341 gatggtttta ctgatgctaa tttagataag gtaatgagtg caagagaaga attagcaaaa
     5401 ttgttaaagg aaatatttaa ttgtgaaatt aaagtaggtt ttgtagataa agataatcct
     5461 gaaatggaaa tataataagt tgttgaatac ttgttaagat attatattta cttaatgatg
     5521 ttaaaaaggt attaaaaaag aaaggtcgta gtaaatttga aaaaaactat aataaagaat
     5581 gtaaatccaa tgattgaaaa taagtttata ggactttttg aaatagagta taaaaacaaa
     5641 ttagatgaag ataaggtttg gatggtagca tcaagaaaaa gtagtgagca attaaaaaat
     5701 atttatttga agaatgaaga agatagtgta gatgcagttg taatagttgg gcttcataaa
     5761 agtagtaaaa aattaatttt aataagacaa tttagagtac ctattaatgg atatatatac
     5821 gagttaccag caggtcttgt tgatgaagga gagtctatag atatttctgt tgaaagagaa
     5881 cttagagaag aaacaggact tactctttta gaaattaaaa aaaataaaag tattgataaa
     5941 gtttatttat ctcctggaat gagtgatgaa tctgttgcct ttgtttattg tatatgtgat
     6001 ggtgatataa cagatgaatt tttagaacca gatgaagaga ttgaagcgct tttaatttcg
     6061 caagaagatg caaaagagat tttacaaagt aatcataaga tagacacaaa agcatttttg
     6121 attttacaaa tgtttgtgag tttaggagct aaattatttg aatagatata tagaaaaaag
     6181 gttatataga agagtaaaat aataaagttt attttacttg tataaattat aatctctttt
     6241 tttatacaat aaagtataat tttgtgtatt tttaaataag tgacttgact cttaaatttt
     6301 cataatatgt tataaaccaa tttaagatac tacaataatt aaaattccaa aattatttaa
     6361 catatttgca attaaaatga gaaaaggtaa aggctgaatg attgaaaaat ttgatgtaaa
     6421 atagtagatt agtttaatac tatagtttgt agggttaaaa attagaaatt gtaagggaga
     6481 taaattctat gaaaaaatta gttattattt taattagtat cattagtgtg gttagcttga
     6541 cagcttgtaa aaaaagcaat gaaagtaaat ataataattt aaacaacaaa gaatcaggac
     6601 aaacaaccat tgaaatggac ttagataaaa attatgatac ttcagaccca tttgttaatg
     6661 cacgtttgtt ttgtgtgtct aatgatatag atgttttaga cacagagatt tcttttaaaa
     6721 tggatggaga tagtggtatt gtggaaataa aggacaataa aacagatgaa actttatgga
     6781 gtaatatatg gcatggaagc gttgataatg atacattcgc aatttctctt tctaatatac
     6841 aaaaagagaa agagtatgct atatgcttta ctggaattaa aataaatcat gcagttgtaa
     6901 aggttacttt tgaaagcaat ttagttaagg agaaagaaaa accctcaaaa taaattccag
     6961 attgtctata acttgatatt cagtacataa aagcagttga tatttatgat tgactgcttt
     7021 ttcttatcaa aaaggatagg ttgtgcattt ttacttgaaa tagtttatgc acatcaaaag
     7081 ttggtgagca tgatattgga aatggtaagc atgaaatctt gataagacaa ggaaataaat
     7141 ttaagttttc aattaagtat atttccataa tttagttaat aataagctaa ttattattta
     7201 tattttgata tataaataat aattgtagca aatctcaaaa aatcatatat tttttgaact
     7261 aaataaaaat ttatttttat tattttaaat tagaggagat tcttgaagat atattatttt
     7321 taaaaataag tatagtttaa aaattcaaaa aaaagatggc aaaatatgtc ccaagggaca
     7381 ttgagtaaaa taaatgattt cagcttattt acactaaaaa gtacatacta aatgaggggt
     7441 aaaataaaga aaaatgatat actaattgtc ttttgataat aaaaaaacat ggaatttgat
     7501 tatttaatca agaaaaagta ttgaacaaat gatttattta gtgtacaata atcatgtaaa
     7561 aacatagtaa tggagggaga catttcataa tgaaaattaa ggtaggaatg aacggatttg
     7621 gaagaatagg aagagctgta ttaagaatag ctcaagaaga attaggagat aatatagaaa
     7681 ttgtagccat aaatgcaaga gcaacaacag aatctttggc acatttattt acatatgatt
     7741 catgctatgg aacttttaga ggtgaagtag aggcaaagga tgaagacact ctagtagtaa
     7801 actctaaaga gataaaaata ttaagatata atgacccaga agaattacca tggaaagaac
     7861 tgggggttga tatagtaata gaatcaacag gattatttac acaaagagaa aaggcagaaa
     7921 agcatattaa agcaggagca aaaaaagtaa ttataacagc tccaggaaaa aatgaagata
     7981 taactatagt tatcggagtt aatgagaaag aatatgataa tgaaaagcac aatataattt
     8041 caaatgcatc ttgtactaca aattgtctag ctccttttgc taaagtattg gacgaaaaat
     8101 ttggtatagt aaaagggtta atgactacag tacattcata tactaacgat caaagaatat
     8161 tagataaaag ccataaagat ttgagaagag caagagcagc ggctgaatct ataataccta
     8221 ccactacagg agcagcaaaa gctgtgtcaa gagtactacc acaattagaa ggaaaattaa
     8281 atggtttttc acttagagta ccaacaccaa cagtttcact tgttgattta gtgtgcgaac
     8341 ttaaagaaaa cgttacatct gagcaagtta actctgtgtt aaaagatgct gctgaaggag
     8401 aattaaaagg tgttttagga tattgtgaca agccacttgt ttctatagat tataaaggag
     8461 attcaagatc atctattata gacgctctat ccacaatggt tatagaagac aatatggtta
     8521 aggtagtttc ttggtatgat aatgaatggg gatattcttc aagaactgtt gacttagtaa
     8581 aatatgtagc tgaaaaatta aaataatata tatttcttaa agcaaatttt aaaaaaattt
     8641 tttaaaaaaa ttatataaaa ctaaaaaaaa agattatgaa aaatattgaa ggaaaaattt
     8701 tttcataatc ttttttcttt catgcaaaaa gatacaagtt acaacttata tttgcatatt
     8761 aggtcgttag agaagtatat atatatttag taaggaatca tactttttat aaaatgaaag
     8821 ataagatgtc gaaaacttgc ataaatctga aaaattttta ttattaaaat actgatttcc
     8881 attttaaaaa tgataaaaaa atgacaaata aagttgcaaa tagtaatact tataagtata
     8941 attaaaaaag agaaaaggtt ttgttaaact ttataacaaa aaaagaaggg atgattcaaa
     9001 atggagaagt taacagacag gagacaggtt aaggcagtaa gcatggaaac cttcattttc
     9061 ctaatattac tagtagttgg ttttgggtat gttggtagta ttatgggagc aggaatgatg
     9121 ttcaaagtaa taatgagtac agcacatgct ttactattgg agacagtttt cttaattatg
     9181 gctatggcag ttcttgcagg cgcattaagc gcactacttt cagagtttgg agtaatagcg
     9241 ttaattaata aaattttcgc tgtatttatg aagcctttat atggactacc tggtgctagt
     9301 atagcaggag ctataacaac ttatttatca gataatccag ctattatacc ttttgctaaa
     9361 gataaaacat tcacacagta ttttaaacaa taccaagttc cagcattatg taacttagga
     9421 acagcctttg gtatgggact tatcttaaca acatttatga tttctcaagg tacagaatat
     9481 gtacttccag cattaattgg taatttaggt gcaattatag gtagtgtcat aagtgttaga
     9541 ataatgttga catttactaa gaagttttat aaatacaatc cggaagaaga taaagcaaca
     9601 ggaacattag agaaaaagga tgaatttaga gaaatcagag aaggaaatgt atttcaaaga
     9661 gctttagatg caattcttga aggtggtaaa atgggggtag atatgggaat ggctataatt
     9721 cctggagtcc tagtagtatg tacattggtg atgttattaa cttttggacc atctacagat
     9781 cctgttacag gtcaagaagt ttatacagga gctgcatatg aaggaataaa attacttcca
     9841 gttattggag ataaacttgg atttatatta gaaccattat ttggatttac atcaccagag
     9901 gcaatagcat tccctataac ttcattggga gctgttggcg cagcaatgtc tctagttcca
     9961 gagtttataa agtcaggagc tataactcct aatgatatag cagtatttac agctatgggt
    10021 atgtgttgga gtggatattt aagtacacat attggtatga tggatgcatt aaatgctaga
    10081 cagttggcag gtaaagctat tctttctcat acaataggtg gtttatgtgc aggagcagct
    10141 gctcacttta tatttacact cgtaggataa atgtaatcag ctaagataaa aaataatata
    10201 caaaaaatgg ttgttgatat gtaataagaa tttacatatc aacaaccatt tttttctgac
    10261 taaagataat ttataataca taaacattaa gtggatatta gagttaagtt atatttatgt
    10321 aaaaagtaac aaaaatctgt agaaatttat gacaaaattt agtacactaa ctatatgttc
    10381 ttatttaaaa tttaaggtta gaattaggaa ttacctagta gagtaagctt tgattaataa
    10441 aagaatcata aaataaaaat attagtcata aagattataa ataacttact taaaataaag
    10501 ccatagaact tacaaaaatt aaaaaagcat ataaatatgg aggggtacaa tggatgaatt
    10561 atttcatata ggaattgatg taggttctac aacggtgaag gttgtggtac ttaataatag
    10621 taataatata gttcataaag aatatagaag acattattct gatgtaaaaa aatcagttaa
    10681 agaagtacta aatggtatat atgaaaaatt gggagatata aatactacca ttataataac
    10741 tggttcaggt ggaattggaa tatcaaaaaa attaggtgta aaatttgttc aggaagttat
    10801 atctagtaca aaatcaatag agtattttca tcctgaaact gatgttgtca tagaacttgg
    10861 gggtgaagat gcaaagataa catatctaag tggaggaata gaccaaagaa tgaatggaat
    10921 atgtgcaggt ggcactggag cattcataga ccagatggca tcacttttaa agacagatgc
    10981 cagtggatta aatgaacttg ctaaagggta taatgttata tatcccatag cttcaagatg
    11041 tggtgttttt gctaaaacag atattcaacc tcttataaat gatggagcca atcagactga
    11101 tatagcaatg agtattttca atgcagttgt cgtacaaact gtgagtgtcc tttcttgtgg
    11161 aagaaaaata gaaggaaatg ttgcgttttt gggtggtcca ttgtactttt tatctgaact
    11221 tagagaagca tttaaaagag tattagattt aaaagatgaa aacataatct tcccagaaaa
    11281 tgcacaactt tatattgcta ttggagcagg attattatca gtagatgaag ataatataca
    11341 actaaaatct ctaatagaaa aattggatag tataaagaat attgaagatg gagaagtaaa
    11401 tttattagaa cctttattta aagataaaaa tgagtatgaa gaattttcaa gaagacatga
    11461 aaaagaaaaa ataaattatg tggacataaa ttcaataaaa agcaattgtt atttaggaat
    11521 tgatgcaggc tcaactacaa ctaaagcagc acttattgat gaggatggaa gacttgtata
    11581 ttcttattat aatagcaatg aaggaaatcc attaaaaaca accattaaag ttataaatga
    11641 agtatatgat atattaccaa aaaatattaa aatattgagt tcaactgtaa ctggatatgg
    11701 agaaggtctt attaaaaaag ctcttaaaat cgataatgga gagatagaga ctatagcaca
    11761 ttacaaagct gctaaatttt tcaacaaaga tgtagatttt atacttgata ttggtggtca
    11821 agatatgaag tgcctaaaaa taaaagatgg agtaattgat aatataatat taaatgaggc
    11881 ttgttcatca ggttgtggct catttttaga gacatttgca agttctttat ctatgacaat
    11941 agaagaattt gcgcatgaag gtatttattc tcaaaatcct gtagatttag gttcaagatg
    12001 tactgtattt atgaattcta gagtaaaaca agctcaaaaa gaaggtgcaa gtgttggaga
    12061 tatatcagca gggctatctt attcagtaat aaaaaatgct ttatttaaag taataaagat
    12121 tagagattta aatgagattg gtaataatat tgttgtacaa ggtggaacct tttataatga
    12181 tttggtgctt agaagctttg aaaaactaat tggaaaaaat gtaattagac ctaatatttc
    12241 aggaattatg ggagcttttg gttcagcact tatagctaaa gaaaaatatg aaagtggata
    12301 caaaacatcc ttgttatcta aggaagagtt gaataatatc aagctagaag caagtgtaac
    12361 tagatgtaaa ggttgttcaa atcattgtct tcttacaata aataaatttt ctgataatga
    12421 aatttttatt tcaggtaata gatgtgagaa gggtgaagct atttatggtg ataaaaaaat
    12481 aggattagaa aagaaaaaac caataaattt atttaagtac aaatacaata gaatttttag
    12541 atacaaacca ttggaaaaag aagaagcaaa aaatggggaa atagggatac caagagtatt
    12601 aaatatgtat gaagattatc cattttggtt tacttttttc aatgctatgg gctttagagt
    12661 tgtactttca gataggtcat caaaacagtt atatgaaact ggtataacta gtattgcatc
    12721 tgaaacagtt tgttatccag gaaaattagt tcatggacat atagaaaatt taattgcaaa
    12781 aggtataaaa aatatatttt atccaagtgt aacaaatgaa aataaagagg attcaaatgc
    12841 agataattat tataattgtc ctgttgtaat atcatattct gaagtaataa aaaacaatgt
    12901 agagaatata agaaataaga acataaatta tataaatcca tttataagtc taaatgataa
    12961 ggaaaaattg aagaaaagac tctatgatga attatcaaga catttttctg atataaaaat
    13021 aactaaagaa gaagttaatc atgcagttga taaagctact gatgaacaga atttatttaa
    13081 aatggagata caagcagcag gtgaaagagc acttaaagaa ataaaagaaa gaaatatgaa
    13141 ggggattgtg ttatgtggaa gaccatatca tatagaccca gaaataaatc atggaatgcc
    13201 agagcttata aattcattag atatggcagt gcttactgaa gactctatat gtcatttagc
    13261 caatgtacaa agaccactta gagttgtaga ccaatgggta tatcattcaa gattgtataa
    13321 agcagctagt tttgtaagag ataaaaacta tttggaactt gttcaactta attcatttgg
    13381 ctgtggatta gatgcagtaa ctacagacca ggttcaagaa atacttaatg aaaaatcgaa
    13441 gatatatact attataaaga ttgacgaagg caacaattta ggagcagcta agataaggat
    13501 gaggtcctta aaagcagcta tgtttgagag agaaagcaaa aatatagatg taaaaaatat
    13561 aaaggtaaac aggatacagt atgctaaaaa taatcagata acgaacaaac atactatatt
    13621 agcaccacaa atgtctccaa tacatttcca attccttgaa aaagctgtta acttaagtgg
    13681 ttataatata gaaattctaa aagatactga tagtagtgta attgaagaag ggttaagata
    13741 tgtaaataat gatgcatgtt atccagctat aatagttgta ggtcagctaa taacagcatt
    13801 aaaatctggc aaatatgatt taaataacac ttctgttact ataactcaga ctggtggagg
    13861 ttgtagagct acaaattata ttggattctt aagaaaggct atatacgatg ctggatttaa
    13921 agatgttcct gtcattgcac ttagtgtaaa tggaatagaa gatagtggta taatggataa
    13981 tatatcacta aaattaatca atagactctt tatgtctgtt gtttatggtg atttgctgat
    14041 gaaagtacta tatagagtta gaccatatga aaaagttact ggaagtgcaa atgctctata
    14101 tgaaaaatgg gttgatatat gcaaatcttc tcttgttaaa gcaaaaattt ctgtatttac
    14161 tagaaatata aaagatatag taaaagaatt tgataattta gagatactag atatcaaaaa
    14221 accaaaagta ggtttggttg gagaaatatt ggtgaaattc catccaattg caaataataa
    14281 tttagtagat atattagagc gagaaggtgc tgaagcagtc gtgccagacc ttacaaattt
    14341 cttcttaagt tgtgccttta atactatata caaacacact catttagaag gaagtagaaa
    14401 gagtagaatg ataggagagg catttatata cataactgga atatatcaaa gagtatataa
    14461 aaaagcactt gataagagtg agagatttta tgctccagcc aatataaaaa atgttgctaa
    14521 aagtacagaa ccagtagtgt cattaggtaa tcaaactgga gaaggttggc ttttaacagg
    14581 tgaaatggtt gaattattaa atgaaggtgt agaaaacatt atttgtatgc aaccttttgg
    14641 atgtttacct aatcacataa ttggtaaggg ttctataaaa gaattaaaga ggttgtataa
    14701 aaatgcaaat ataataccta ttgattatga cccttctgca agtgaggtaa atcaacttaa
    14761 caggataaaa cttatgcttt ctaaggcttt taaaaatata taagatttat attttgatat
    14821 gttaaaagtt aatgaattta aaaatatact ctatattaag tatctataaa aaagagttat
    14881 cctatttttt agggtaactc tttattagtt aaaaaattat atgtatactg atattaaagg
    14941 ggggaagtaa tatgagttta gtatatgatg tttataaatc aaaattagga aatttgtaca
    15001 tattaagtga agatggtttt atagttagta tatacatagg agatgaaaaa tttaataatt
    15061 taaaaaatga atgtattaaa aaaggaattg atataaagag aagtaaggaa gatttaaagg
    15121 aagcaataag ccagatagat gattacttta atggaaaaag aaaagtcttt aatttaaata
    15181 ttcgtattga agggactgaa tttcaaaaat cagtttatag ggaaatgtta aaaatacctt
    15241 atggagaaac attgtgttat tcagatatag caagaaatat aaacaatcca aaatcagtaa
    15301 gagcaatagg acaagcaagt aaaagtaata aaattccaat aataatacct tgtcatagag
    15361 tagttggcaa aaaagatatt ggtggatata tggggaatca ttctgatttg aaagagatac
    15421 tattaaattt agaaagacag agttaactta gaaagaaatg tttttattgt taatatttga
    15481 tataataata gtaaaaagaa gtatttttta caaaaacaat gaagaattta ttttaattta
    15541 caaaaatgag ggggaatttt aatgtgtgat aaagttatag catcaaaata tcatgagaag
    15601 ggatttaatt gtgcagaatc agttataaaa gcatataatg aggaatttaa tacagatata
    15661 ccagtttgtt taggaagtgg actgggttca gggtgtgggg ttgctagttt atgtggtgca
    15721 gtaaatgcat caaatataat aattggatat gtaaaaggca gaaatcacga agatgaaagt
    15781 actaaagcta aagtatatgc taaagattta actacaacag taagaaaaga gtatggttca
    15841 gagttatgta tagacctaaa aaaagattta gttgcttgta gagaaataat ggattttgca
    15901 tatgatagtc taaaggaaac tttaaaaaaa gaattataag aaaataagct atcaagtata
    15961 aattatttga tagcttattt ttatagtcga tactaaataa atcaaatata ttttagaatt
    16021 attatttgta aataaacagc aaataatttt aggattttta tttaatatag tttttattta
    16081 tatttatttt tgaatatgtt atactttgtt taaataaata tttgtaatga gggagatgag
    16141 aagattgaag aatctcaatt tacttattaa taaattatat tcaaaaaatc ataatgaagc
    16201 atataaaact tttttattct tagaaaatga aagtttaaaa tcaaatatta catattgttt
    16261 ttttgactca ttcctagaaa tgattgataa cgaaaactca tatattcgaa caaggggatt
    16321 gttattaatc tctgcaaatg ctcagtggga tattgataat aaaattgaaa taaatataga
    16381 tagtatacta agtcatatcg tagataaaaa accttctgta tcaagaatgt ttattaaatc
    16441 catacctaat attacaaagt ataaagaaaa tcttattaat cgcataaaaa tggaattaag
    16501 taatgcagat ataagtattt ataataataa tatgaaacca ttagtagaaa aggatataaa
    16561 cgatacatta tctaatatta gttaaatatt aatatagaaa ttgaatatta tctagttaca
    16621 attatttata actaagataa taaaacaaca atggtgctaa tttatatgta taaattaatt
    16681 atgaaaaatt tatataagta aaatatatta acataaaggt aaaattttgt atactaaaag
    16741 ggaatattta cagtttaatg gcagttttaa aataataaat taaagctgtc atttttattt
    16801 aaaaattttt agaaaaagta caatagtgtt aatgtgtgaa ttagataagg tgtatataat
    16861 agtttagatg atatgatata aaatatgttg taaattaaat gttttctttg acaatatata
    16921 cacaaggatg ataatatcta tatgaataaa agatagtgtg taatttgata atatgtaatt
    16981 ataacattat gatataatta caataaagta tgtaataatc tgtagaaatt tcaagctagt
    17041 tatctaagtc ggataactaa atctaaacgg aatacataat gtattaaata aatgatgata
    17101 ctaaaatgat actattttta tagaaattta ttgaggtata taattaatga aaataatata
    17161 ttaaattata taatatattg agttttacat aaaagcaaag gtgggaataa aaatgaaaga
    17221 aattgctgat gctataacat cagagtattt aagctatggt atcaatgaag atattagtat
    17281 ctatgaaggt agattttgca tatatttaga taaaaaatat agatgtaatg ggaaaattta
    17341 ttataaaatg acacctccaa tatctataag ttttaaagca gacataggtt gtgttgaaga
    17401 gatagacaat gaagatgaca atttagcttt agattatgat aatgctattc ttgaagttca
    17461 tggatataaa attatttcta taacaataaa tactttaagt gaatttagtg tagaaggtta
    17521 tatcaatgat gactgcataa aatctaagaa ctcctatgtt gaatatgtag attttaatat
    17581 aataaactta gataaaatac ctggaaaact cattaaatac aatgataagg tatacgcagg
    17641 tagaattgaa tttgatataa atgattatgt tgtaactata gacaagcgat atgattatag
    17701 aaaagaatta aaatcagaat taaagtctaa atctggagca ataataactc atataggtag
    17761 gattagaaga aaagatggta gaatttttag aacaaataat acaataaatc ttttagatag
    17821 gatatcaaca gctttgagtt ttatgtgtgg aagatatgta gggttttgtt tggccaaagg
    17881 gtatagaagt ggtaatgaag tttatagaat atggaatgaa aatcaaatat ctccttttag
    17941 atatgtacca acatggtcag atacactttc aaattatcat aatatggaaa aatatataag
    18001 ccttatgtgt aaaaagctag aagattttta ttatggttct gctataaaga gtgttgttga
    18061 ttggtacata gaatctcttg gaagtgctac catggaaaac aatataatat ctgtacaaat
    18121 tgcacttgaa actttgtcat atgtaattct agtggaacaa aataagatac ttacagatga
    18181 agcatttgac tgtaatttgg catctaaaaa tataagactc ttacttgata catgtaagat
    18241 accatatggt aaacatgaat taaatatatt tgataatata ataaaaaata aatttgatga
    18301 tggagtggat ttagttattt atttaagaaa tagtatagtt catccaagta gaaggactca
    18361 tagagctgtg ttagaggttg aagatatttg gaatataatt tcaataggaa cgagatatat
    18421 tgaacttgtt ttactcttta ttttaggtta tagaggagaa tattcaaaca gattagtaga
    18481 aagatgttat ggtgaagtgg aagttgtacc ttggaactag atttttatat ttattttaaa
    18541 atatatattg acatatattg ccttatgcta taaaatcaat atcataataa taattcagaa
    18601 taacattaaa tgctaagaaa agaaatagta aaagtagtta atcttaaaca gagagtttcc
    18661 gattggtgag aggagcaata gattttactt tgaacacatc tttgagcagg actctgaaag
    18721 agtagaaata ctttattagg agatttccgg aatccttgca cccgttatag tgctagagta
    18781 taataatttt attgtactta aagaggttag tgtcgtgagg cattaatgaa cagaggtgga
    18841 accacgagag ttaactcccg tcctctagca gaagctagag gcgggagttt tttaatataa
    18901 ttttttaagc gcgcagagaa ttatattgca atagatacac tttttaaaaa ataatcaaaa
    18961 tattttaaaa attaaaagac gagggagaat attatgaaaa atatattaaa aaaagtagga
    19021 atatttacaa ttatgttagg tttattaggt ggagttgtag gttgttcaaa accagataat
    19081 gaaaaagata aggatgcttc aaaggaatct aaaaaagaag tagttgtagg gtttgataat
    19141 acgtttgtac caatgggatt tttagatgaa aagggagaaa cagtaggatt tgacgtagac
    19201 ttagctaaag aaacatttaa aagacttgga atggaagtta agtttcagcc tatagattgg
    19261 tcaatgaagg aaactgaatt aaatgattca aaaactgtag atgtattatg gaatggatat
    19321 tctataacag acgaaagaaa gaaaatagta tcatatacag aaccatattt acaaaataag
    19381 cagataatag ttactctaag tgactcaaaa ataaattcaa aagctgattt aaaagataaa
    19441 gaagttggaa cacaacaagg ttcaacagca cttgatgcag tggaaaagga taaagatttt
    19501 atgaatagct taaaaggtgg agcaccagtt ctttatgata cttatgataa agcacttaga
    19561 gatttagaga taggtagaac tagtgcagtt gttggtgatg aagttttaat tagatactat
    19621 atgggacaaa agggtgaaga caaatacaag gtattaaaag acgattttgg attagaagat
    19681 tatgttgtag caacttctaa agaaaatcca gaactttgtg agaaaataaa tgaaacatta
    19741 aaagaaatga aaaaagatgg aacttttgac aaaatttatg ataagtggtt taaatagaag
    19801 ataagttagc tgttaagaag ggggcactaa aggcatgtta caaggtttag agatagttat
    19861 agcaatgttt tgtataacat tgatagtatc aattccattg gggattggag ttgcattttt
    19921 aagattatca aagaataaat tagtaagtgg tattacacaa tgttatatat tgataatgag
    19981 aggtacacct ttacttttgc aaatgatagt catattttac ggattacctc ttttaggaat
    20041 tgtatttgac agatttacag ctggagtagt agctttcttc ttaaattatg cagcatattt
    20101 tgcagaaata tttagaggtg gaatacagtc aatcgataga ggacaatatg aagcttcaaa
    20161 agtactagga tttgataagt ttactatgta taagagagta atctttccac aagtttttaa
    20221 aagaatacta gcacctattt caaatgaagt aatcacatta gtaaaagata catctttagt
    20281 atatatatta ggattaaatg atattttaag aatatctcaa atagcaatga acagggaagc
    20341 aagtctgtta ccattatttg aggcaggagc gatatatctt atatttgtag ctatacttac
    20401 taagggattt gaattacttg aaaaaaaata ttcttattat agataaagtt acaatattat
    20461 aggaggaggt tttttatatg ttgaaaatca aaaacttaaa taaatcattt aaaaaaaata
    20521 gagtacttaa agatatttct tttgagttag aagaaggtca gattggagtt ttacttggta
    20581 agtctggtgc aggaaagacc acaatattaa ggtgtataaa tggtcttgaa gaatttgata
    20641 gtggagagat tataatagat aatgaggtaa taaaaaataa gagagatatg gcaaaaatac
    20701 gaggaaaaat aggtatggtt tttcaaaatt tcaacttatt tcctcatatg acagtccttg
    20761 aaaatataat tgaatcccca gttaatgttt ttaaagttcc tagaaaagag gctgaagaga
    20821 gggctagaga acttttaaga ttagttgatt tagaagataa attaaattct tatccatttg
    20881 aattgtcagg aggacagcaa cagagagttg ctatagctag gtcatgtgca ttgatgccaa
    20941 aagtcctttg ttttgatgaa cctacttctg cacttgatat tgatactatt caaagagtag
    21001 tcaatataat gaatagactt aaagacaaag gtatgacaat attaataatt acacatgatg
    21061 ttgtcttctc aaataatgtt gcagataaaa ttataagtat aaaagatggt atagtagaaa
    21121 atgttcaaat aaaagaaaaa attgtttaga gttttataaa tataaactag ggtagaattt
    21181 tataatataa ataaagggca agtaaaatca aatatactat gcccttttgt tatctcaaaa
    21241 tttaatctta tattttatgt ttaagttaca ttataattta taataaaaat aaaaggacta
    21301 tttaaatata taatgtgaat aaatgtttaa taatttgaaa tatgataatt ttttatgttg
    21361 aaagcttata atgattatga tataaattgg ttatagtata caatttatgg gtataacaat
    21421 aaaaaattag aaaggaattt ttataaaatg attaaattat atggatatac aaaatgctct
    21481 actgttaaaa aagctaaaaa ttggcttaag gaaaataatt tagaatttga agatatagat
    21541 atggttcaaa accctcctag taaagaggag ttaaaatcaa tttataagac tagtggatat
    21601 gatataaaga aattttttaa tacaagtggt atgaaatata gagaattggg tcttaaagat
    21661 attgtaaaaa ctgaatctga tgataaactt ttagaaatat tggtaagtga tggtatgctt
    21721 attaaaagac cattactttt ggatggtaaa aatgtattat tgggctttaa agaagatgta
    21781 tggaaaagta ctttgctaaa agaagattag gaagagatag gtgtgttgat taaaattatt
    21841 aattaataca cctataaatt tatgcattaa atctaatttt tataaatatt aattagcaaa
    21901 ttcaaatcaa aaaaattcat atcaacaaac atattacttc ttattacaaa ttatatcata
    21961 tgttttatat taaaatatta aaatattaca acgaattgtt acaaaattac ttattattaa
    22021 ccatgaacat ttgttttgtg ctatcatatt tatataaggg aattgtcata aaaaatatct
    22081 tgttcataca gttttatata gaaaaaagaa atgaatcttt tctttatata agtatatttt
    22141 gtaaattgcc tctatattta tagtttaaat aatagtggta ttaaaaatct gacaacaaaa
    22201 ataaaacttt caaaaaatta aatctaaaaa gaataggaga taaatatgag tattgaagat
    22261 ttatatgatt ttgaatgtgt tcctttgaac aatgagattg atattgatgt tttatttgaa
    22321 aagatgatag aagatggaaa agaaaaagaa tatacaccaa ttatagtcat tgatgaaaaa
    22381 gtagggctat taagaaaaaa tatagatatg attactaaag agtatggttc tcttgaaaac
    22441 tatagagagt attgtttaac aaaatataat gaaattgatg taaatcaatt ttttgatttt
    22501 aggaagagtg agatttcaga attattaaag gagctaattg atttagaaga tgatttttat
    22561 gattataaac attttagacc aattatgaat atagatatat ttcatgaata taacaaagtt
    22621 tacatagcta aaattccaac aattaaacca tatgaagtat ttgcatacat acctattggc
    22681 ggatttaatg attgtcctag agatgaagaa catatagcta ttgcaaaata ttggtatgaa
    22741 aagcatggaa tctttccaat cgcaattgga tgtgatacag ttcaatattc tgtaaaaaat
    22801 ttaactaaag atggtaaaaa atttgatgac ttatgtattg aattagtatt ttattgtgag
    22861 gatattatta tacaagggta tgaaacctta aaggctctta aggatgtatt aaaacgctct
    22921 acaatagtgc ttttttggtg ggattgatat tctatcattt agatagtatt aaattgttag
    22981 tcaccaagaa tccacttgct ttagttatgg ggagtgtgtc aaactaggtt tttatacaca
    23041 gtgtagcata gtaatatgtt taaattacaa aggttaaaaa aatactttaa tatttttaac
    23101 attataatta atagatttaa aggtaattat aatttataaa ataaatactt tatatgttat
    23161 aatcattaag aatgtaaaaa aataatatat agttttatag ttcatatttt tccagatatg
    23221 gaggtaaatt ttgtgaagga aaaagaaaaa ttagataaat taaaaaaaat gttacttgaa
    23281 ttaggcagtg ttgtagttgc ttattctggt ggagtagata gtaatttttt gcttaaggtc
    23341 gcaaaagata cattaggtga aaatgttata gctgtgacta ttcatgcaat gatgcattca
    23401 agtagggaaa ttgaagaggc taaacaatat actcaaaatt ttggtgttaa acatatcata
    23461 ttaaatatag aaaactttga tttaaaagaa tttaaagaaa atggtgttga tagatgttat
    23521 cattgtaaaa aatatatatt ctctaaaata aaagaggtag caaaagaaca taatataaag
    23581 tacatagtag atggaacaaa tatagatgat ttaggagact atagacctgg gcttaaggca
    23641 ttaagtgaat taggagtaat tagtccatta aaagatagta gtttaaaaaa agaagaaatt
    23701 aggtcgcttt caaaaacatt aggattaaat acttttaata aaccatcatt tgcatgtctt
    23761 gcgagtagga taccttatgg agttgaaata acagatgaaa atttaagaat agtagaaaag
    23821 agtgaagaat atctatccaa tttaggtttt tctcaattta gagtgagaat gcatggagat
    23881 atagctagaa tagaagttgg acaggaagaa ctaggtaaat tttttgaaaa taacaatttt
    23941 aataaagttg atactaaatt aaaaatattt ggctttaaat atgttacact agatatgtca
    24001 ggatataaaa tgggaagtat gaatttaaat gtgtagatta ttttaaaaat aaataagttt
    24061 tatagttaat ataaggaaac aggaggtttt atgaaaaatt atacgttaat atcgccatgt
    24121 ttttttggaa tggaaaaaat gctggctaga gagattacta atttaggata tgaaataata
    24181 aaaacagaag atggaagaat aacatataaa actgatgagt ttggaatagc aaagtcaaac
    24241 atgtggttga gatgtgctga aagagtacat cttaaaattg ctgaatttga ggcaaaaagc
    24301 tttgatgaat tatttgaaaa tacaaaaaga ataaactggt ctagatatat accttatgga
    24361 gctcaatttc ctatatcaaa agcttcctct ataaaatcaa aattatacag tacaccagat
    24421 gtacaagcca tagtaaaaaa ggctatagta gaaagcttaa agaaaagtta tttggaggat
    24481 ggtttgctta aagaagataa ggagaaatac cctatttttg tatttataca caaagataaa
    24541 gtaaccattt ctatagatac aacaggagat gctttgcata agagaggata tagagaaaag
    24601 gcaaataaag ctccaataag agagacttta gctgctgggc ttatttattt aactccctgg
    24661 aaagcaggta gagttttagt agaccctatg tgtggttctg gtactatatt gattgaagct
    24721 gctatgattg gtataaatat ggcacctggc ttaaatagag agtttatatc agaaaagtgg
    24781 agaattcttg ataagaaaat atggtgggat gtaagaaaag atgcttttaa taagatagat
    24841 aatgaatcta aatttaagat ttatggatat gatatagatg aagaatctat agatatagct
    24901 agagaaaatg ctgaaatagc aggtgtagat gaatatatag agtttaatgt aggagatgca
    24961 actcaattta aaagtgaaga tgagtttgga tttataatca ctaatcctcc ttacggagaa
    25021 agattagaag ataaagacag tgttaaacag ttgtataagg agcttggtta tgcatttaga
    25081 aaattaaaaa attggtcgta ttatttgata acttcttatg aagactttga atatgagttt
    25141 gggcaaaaag cagacaaaaa aagaaaattg tataatggta tgttaaaaac taactttttc
    25201 caatatccgg gtcctaagcc tcctagaaat aataaataag ttttacatga tttatttgta
    25261 aaatataaaa ttttattaaa ataagtaaaa cattatgatg ccttgaaacg tctaattatt
    25321 gtgaggagat ttttgtgaac aaatttaaag atttatagga ttaggaggag ttaaatgaaa
    25381 gtgttaaagc ttattactgt agtagccctg atgatgttat ttgttactgg atgtaatata
    25441 aaaactgaat ctccagaaca attagcgaag atacctgact atgatgatac aaaaaaagta
    25501 ttgtatgatg gtattgacca gttactaaaa ccagattcat ctatgatatt gccttctaat
    25561 acaaaagaag taggaaaaat aaataaggta gatttaaaca gcgatggaat tgatgaatta
    25621 gtagtatttg aacaaaaaga agatttaagt aataatgtga gtcaggtagg gtttgtaacc
    25681 ttgagttaca atggagaaaa atacgtactt ggagaccatt ttttagaaaa tggcgaatca
    25741 atagaatatg ctaattttta tgatttggac tcagatggat ataaggaagt tatcttattg
    25801 gttaaatcca aagacaaaac gaatatgcat atatataaag tagtagataa tgaaataaca
    25861 aaaatatatg acttggatgc atcatggctt caaaataaag aagattttaa tgacatgaaa
    25921 gtaaaaattg gatatataga tggagatgac aagttagaca tattgatgct tcatttgaat
    25981 aataagacta atgaaatgtt tgcaagtgtt gcaaattttg atgggaaaat gaaaatcaaa
    26041 gattctgtta agtttgaaaa tgtaaaaaac ttaagtgaat tatatataac attaggtaat
    26101 gttgcttcat ctattggaaa ttcttctgca gctataaaag gtattgtact tgatattcct
    26161 atattgaaag ataataacta tattacgcag atactttata tgaaagatgg gaaaattaac
    26221 aaagctttta gtgattatga taaaactatt actaaatctt attatatacc tgtagatgat
    26281 attgacaaag ataagattat agaaatacct atagttgcag gcagtacagg taataataaa
    26341 aatacttata gttctaaatc atctgcaact ataagttggt atagatggaa tggaaaagaa
    26401 ggtgctgact caagtttaat atttacaagt cagatatatt ataattataa atataatttt
    26461 aaattattta ttccaaataa tttatttgat aaaatacttg ttgaacagga atttgttgga
    26521 gaaaaagcag tatttaaatt ttactatttt gactattcag accgtaagaa tttatttaat
    26581 atagtagtag agagtaaaaa taaacttgaa gatagaaaaa atacaggtac tcaaaattct
    26641 attgtacttc aagagagcga tgaatatact ttcttactag ttgtaaacaa tgcaaatgaa
    26701 atggataagc tagatatgac tatagacgca ttaaaagaat atttctcatt aatatatggt
    26761 taatattata ctcaattgga ggttttattt tatgaaggaa aagatactta tactagaaga
    26821 tgaaattggt attagaagtt ttgttagtat aaacttaaaa agggaaggct atgaaatagt
    26881 tgaggcaggt actggaagag aagctataga aaaaatgaca acagaaaagg atattacaat
    26941 agctctttta gatgtaatgc ttccagatat aagtggtata gaagtatgta aatttataag
    27001 ggagaatttt gaccaagtag gtataataat gcttactgct aaagctcaag aagatgataa
    27061 aatagaagga tttatctcag gagcagatga ttacatcata aaaccattta gtataaaaga
    27121 gcttttagtt agagtttctg ctcttcttag aagagtagca aaggatgatt caagtgttaa
    27181 gtcgagtgag atagtttctc caccatttat acttgatata gacaaaagaa aattatttaa
    27241 aaatggaaag gaaattgagc ttacaccaac tgaattttca atagtgaaat atctaatatc
    27301 aaatgctaag cagtcgttaa gtagagacca gatattagac gaagtatggg gaactaacta
    27361 tttatatgat tttaaaatag tagatgtaaa tataagaagg ataagaaata aaatagaaga
    27421 tgacccatca aaaccaaaat atatacaaac tatttggggt tatggatact gttttagaaa
    27481 ggaagaataa tagtgttaca ttttgaaggt ctgagaaaaa aagtaataaa aaactatttt
    27541 ataataatta ttataatggt tactctgttt gaaggattgt tcatgtttta catacaaaac
    27601 tactattatg attctgtcaa acagctactt gaatctgaaa taaaatatgc tgatgaatat
    27661 aatgctatta caatggaaac tacaagtttt gagaaaaaag taaaaaatat atttgataaa
    27721 caacccttaa ctaaaaattc agaatttgga atttcaataa tagataaaga taaaaatatt
    27781 atattagacc aatatggttt taaaagtaaa gaaaaagcaa attatgaaga tgttaacaat
    27841 gcattaaaag atataaaaac taaaaattta acaccttata cttatagaat accagataca
    27901 ggggagcatg ttatgagtat ctccttacca cttaaggtaa ataatataat agaaggtgtt
    27961 gttagatata cagtatcatt agatgctatt gataatgcga tattaaagca agctacatgg
    28021 cttatattag caggaatatt tatacttatt atagctatac taataagtct taaatttgct
    28081 gagactctta taaaaccatt acgagagcta aagaagtttg caaatgaatt ggctgtagga
    28141 aattataata taaaattaga aaagatgaag attgtagatg atgaaattgg tgatttagca
    28201 cagacatttg aacacatggc acatgagatt gacaaaagtg aaaaattaaa agaggaattt
    28261 atatcatctg tatctcatga actaaggact cctcttacat ctataaaggg gtggagtgaa
    28321 accttaggtt atgaaagtat aacaagagaa gaactagact taggtttagg cattatacaa
    28381 gatgaaacag aaagacttat aaaactagtt gaagaattat tagacttttc aaggctttct
    28441 tcagacagga taaaacttca tgttgatata gttgatgttg aaggtttaat tgtaggtgtt
    28501 gtaaatcaac ttaaagttaa agcagctgaa aaagatatat cacttttatt tgaatttgaa
    28561 aatgaattta tagagaacat tcaaggagat aaaaatagat taagacaggt tctcataaat
    28621 ttaatacaaa attcatttaa atttacgagt caaggtggtt acataaaagt tgtagcttct
    28681 caagatgaag agataacaac catatcagta gaggataatg gttcaggtat agaaaagcaa
    28741 aatttaaata aagtgttaga taaatttttc caagaagatt ataataaggc tggtagtgga
    28801 ttaggactag caattagtaa tgaaattgta aaacttcatg gtggaagaat gaaaatagaa
    28861 agtgaaaaga atgttggaac aaaaataact tttaatataa aaaataaatt tgctaaacaa
    28921 gcataaattc ttagaaagag gattaagatg agaaacataa aaatgatagt agcatacgat
    28981 ggttcaagat ataaaggata tcaaaaatta ggtgacaata atatgactat tcaagaaaaa
    29041 cttgaaaatg ttttaagtaa aatgactaat gaaacagtgg agataatagg ttctggaaga
    29101 actgatatgg gagctcatgc aagaggacaa gtggtaaatt ttagaactaa ttgtatggat
    29161 tctttggata aaattcaaaa atatttatat gaatatttac cagaagatat agttgtaaaa
    29221 actgttgaag aagttgatga aagatttcat tcaagataca atgtaaaatc aaagacttat
    29281 atgtataaaa ttgacaataa taagtatcat aatcctttta taagaaaata tgctactcat
    29341 gtaagtaaaa aattagattt agatagaatg agaaaagcaa gtgagtattt agtaggagaa
    29401 catgatttta ctagttttgc ttcttctaaa tctaagaaaa aatcaaatgt aagagaaatt
    29461 tattctataa atataaaaga agatgataat gttatagaaa tatatgtaga aggaaatgga
    29521 tttttgtata acatggtaag gataatagta ggtgctttga tagatgttgg tctaaaaaga
    29581 agagctccac aagatattaa gtatatgctt gaatcaaaag atagatgtca atcatcagat
    29641 actgcaccag ctaaaggact atgtctttgg aaagtaacat attagtcaat tatataaaac
    29701 tctctttaaa ataaaaataa aataaattat atagttgaca taaatggaaa aataaactat
    29761 tatatatttt ataagagaga tataaaactt tatatttaaa tcctgtgaga aagagagtaa
    29821 cttctatgtg ttttatagag agctgaggat ggtggaagct tagcaaataa gtattagtga
    29881 aaagaacttt ggaggatact aattgaattt agtatgttag taggtaatct cgccttaaga
    29941 gaaagagtgg ataagtttat cttatcaatt agagtggtaa cgcggatata tttcgtctct
    30001 tggtttttcc aagaggcgtt ttttaatata tttaattatt agtgtttatc tggtatgttg
    30061 aacatttact aattgattag ctaagtttat caataagagt ggtaccgcgg atatttcgcc
    30121 tcttagtatt ttaaaatact aaggggtttt tttagtatta aaatgatttt atgtgagtct
    30181 aaattctcag agtcattcaa tattaagaat ttctataaaa taaaaattat aatttaagat
    30241 tgggaggaat taaaaatgaa ggaaaaagta gtattagcat attcaggagg acttgacaca
    30301 tcaatcataa taccttggtt aaaggaaaat tatgaagata tagatgttat agctgtttgt
    30361 ggaaatgtag gtcaggaaga taaaatggaa gatgtatatg aaaaagcttt acaaagtgga
    30421 gcatcaaagg catatgtgga tgatataagt gaagaatttg taactgaaac tatatttaaa
    30481 gccgtaaaag cagaggctaa atatgaagga aaatacttat taggaacttc tttagcaaga
    30541 cctataatag ctaaaaaatt agttgaagtt gctcataaag aaggtgcaaa atatatatgc
    30601 catggatgta caggaaaagg taatgaccaa gttagatttg aagctacaat tgcagctctt
    30661 gacccgacta taaaagttat tgcaccttgg agaatttggg atataaaatc aagagaagat
    30721 gctatagact atgctgaaaa acataatata aaggtaacag caactaaagc taaaatatat
    30781 tcagtagatg ctaacctttg gcatgtttca acagaaggtg gagatataga gcacctagaa
    30841 aatgaacata aaaaagatgt ttataaacaa tgtgtagacc cagaagatgc atgtgatgta
    30901 gctgaatatg tagaagttta ctttgaaaaa ggtgtaccta aaaaggtaaa tggcgaagaa
    30961 ttatctccag ttgcactgat tcataagtta aatgagttgg gttgtaaaca tggaattggt
    31021 gttatagata tagttgagaa tagacttgtt ggtatgaaat caagaggtat atatgagact
    31081 ccaggaggaa caatccttta tgaagcacat aatattttag aaagtgctac tttagacaaa
    31141 gatacattac atttcaaaca aatggtatct tataaatacg gagaacttat ttacaatgga
    31201 ctatggtatt gtaaattaag agaatctata gatgcattta tggaacaaac tcaagataat
    31261 gttacaggaa cagtaaaagt taaactttac aaaggaaata taaaacctgc tggaatattt
    31321 actgaaaatg ctctttatga tgaaggaata tcttcttttg gaaatagtga actttatgac
    31381 cacaaagatg cagaaggatt tattaattta ttcactttac cattaaaaat cagagctatg
    31441 aaagctggaa aataataaaa taaattattt aagagtgtat aaaaactatt tttaggtttt
    31501 tatatgctct ttttttattt gaatttatta aattatacag taaatagtat aaaaaaatat
    31561 attatagttc caaatggctt aataatgtga aaatataaga cctaaaatat aaattttata
    31621 aatacaatag ttattgactc tctcattgta agagggttta tactgaatct aatgaaaatt
    31681 tatagtgagg agatagatta tatgagaaaa ataattgaaa ttaaacatca ttcacatgat
    31741 tatgagtgta tgtggaatgg tatagaagat ttatatataa ataaaaccgg tgaatgcctt
    31801 ccaaacgatt ttttcttttt actgtcaggt tttggttcat tttgttatat gaaaacaaat
    31861 aaagctgatt tgaaaagaat ggtagctttg ggagatggaa ggacaaaaca gatgtataaa
    31921 tttttagcac caattgttgg atttgaatac aaacatcatg agtttaaaaa gtatgagcaa
    31981 gcattaaaga aagcaaaatc tgaaattgat gatggatatc cagttatttt aggagcttta
    32041 gatatgtatt atctaccata ttataagaag ctatatcata aagaacatat tccttttcat
    32101 tatatattaa tggtaggata tgatgatgaa ggaatatatc tgtatgattg tggtagaaca
    32161 gaattattac atctttctta tgataaatta cgtgaaagca tgaattgcaa ttcccctgga
    32221 ttaagcaaag aaaatactat ttgcacaata agaatgaata cttcaaagaa taaatataac
    32281 attgctagag aagctattgc tataaagcgt gatatgtttt taaatccacc taaaggattt
    32341 ttgggatata aaggttttga aaagtttatt aaagagttac cacagtggaa cactgaattg
    32401 gataaagatg attatgataa gattttgacc aatatggtta tgttttttgg aacagtacca
    32461 acaattccaa atgcaatcaa aggaattaaa gaaccagata ctgttcaatt taaaggtgga
    32521 tttgataaaa tgagtagaat gctcaacagt attggggagg aatacaaaaa cgactctttt
    32581 atacaagtag ctgatatttt tgataaaact gctattataa ttgagaaaat atccaatatt
    32641 ataatagatt acttaactca aacatgtgat gatacagaac aacttccgtt attgttctct
    32701 gaggtcttag agcatatgaa aacaggatat ttaatcttgg atgtataaaa aatatattgt
    32761 tgaccctaac attacgtaat agtgtaatat gaaaatatag cttgaatata ttagtaggta
    32821 ttgatggctg taaaattaaa atttgaggtg tggatatgag aacagtgaaa caagtttctg
    32881 atttaactgg aataagtgtg agggcattac attattatga tgaaataggt cttttaaaac
    32941 caaataaaat tacagatgca ggatatagac tttatgatga tgaatctatt aaaactcttc
    33001 aacaaatttt attttttaag gagattgata ttcctttaag agaggttaag gaaataatgt
    33061 caagccaata ttttgataag gttgaagctc taaaaaatca aaaaaaatta cttattttaa
    33121 aacgaaagag actggatgaa ttgatagagc ttataaatca aactctaaga ggagaaggaa
    33181 atattgattt taaagagttt gatatgagcg agtattttga tgttttagaa gaatttaaaa
    33241 gagagcatag gaataaggta attaaaattt atggtagtgt agaaaaatac aatgaatata
    33301 tagaaagagt taagtctaat gaagagaaaa ttgctaaaat ggctataaaa caatatggaa
    33361 ctattgagaa gtttgctaaa gctataaaaa caaattttag cagtgatata ttgaatttag
    33421 gagaaaaatt tgatagatat aaaaatgatt gtttaaaaga aaaacatcca aaattaaaag
    33481 aattatatag aaagcttgta gaagatttaa gtaggaatcc ttcttcaaca gaccttcaag
    33541 aaatagcaaa agagataaca gatatatcta aaaaagatta tgaaattttc tctatggata
    33601 ctggtgatga caactggtat tatatggttc aaaattatct agtaaatcct atgtggatag
    33661 aagaagtaga taaaaagtat ggaagtggag caggaaagtt tattggacaa gtactaaaga
    33721 cttatctaag agatagaaaa ccaaagataa atacattgta tgaaaaactt gtagaagatt
    33781 tgagtagaga ttgttcttca agggaagttc aaagcattgt tgaagaaata gacaatgaaa
    33841 tgaaaagaag taatgaattt tataaaatag acaatggtga aagatacttt gattatatgt
    33901 cagagcttta tttacaagat tctgactata taaaagtaac tgataagaat tatggtgatg
    33961 gtgcatctaa gtttattgga gaagctttta agatttattt tgataataat aattgttgaa
    34021 aatttgaaag taaaaaatat gcaagtttta taaaagcaca aaaataagga tgtagattag
    34081 ctccatctat atccttattt aaagttatta aaatatatag tttacatcaa acttaacact
    34141 ttcaataata tttcccaaat atgtttttat actttcaact tcttctaaag attttaattt
    34201 attttcagta taaattgctt tgtccagaat attaaacctt aatcctattt catcaaagta
    34261 ctcatgattt aaaactttgt accaatggtt tttttcttta ttccaactcg tagatattga
    34321 atcagcttct ttttgagctt tttcccaatc ttcattttct atagattttt ctaaaacaga
    34381 tatattgtct ttatatcctt ctgtaaaatc atatagttta ttgttaacat aaaatccaaa
    34441 taatacaaat aagatagtcc atagtataac aaatgttgta gatttcaata ttaatcaccc
    34501 tttttatttt gaataaatat tttgtcattt tcatctaaaa cacaaataag aacatcttta
    34561 aaagtttcta tgtgattaga ttttaaaata cccattaacc agttagtatc tttttgagct
    34621 atgtctagat ttttatttat tattctacca tccagtataa gtgggatagg taaatgatta
    34681 aaagctcttg gaggagtact attgtagctt gatgctggta caacacttag attaccatca
    34741 gtctccaaaa tagcatattg tacatctttt aggttaaagt atccttgaat cctaagttgt
    34801 tctaataatt catctatact aattctttct tttttaagct ctttatatac aatttttcct
    34861 ttatctatta atacagaagg tttacctgat aaaaatgaac ttaattttct actttttaat
    34921 gataagaatg aaattagagt ctgcatgatt acaagtccag atattgctgc aacaccattt
    34981 atgattggta tattattatt ttccattggg acagatgcaa cttctgcaat taatagtgtt
    35041 ataactaaat caaaacagtt catttcagct atttcacctt ttcccatgac tctaagtgca
    35101 attagcactg ttatgtataa tataatactt cttattaata ctactgtcat atctatcaat
    35161 tactccttta aaaaatattt acacttagtt agtatatcct atataaaaaa tttaattcaa
    35221 agtataaaaa accttaaata attggattca actatttaag gtttttttga taattttaat
    35281 attaaatttt ttatggattt tctgttactt ttatttattt taataacaga ttcaacaaaa
    35341 ctctttttat ctcctaattt taagataaaa tcaggatatt cttcaaattc attgagtttt
    35401 attaatttga aagaagaaga tagattttta aagttaatag ttttagagtt attcactaat
    35461 acacttcttt ttttaaaata aatttctttt ttacttatat ttagtatagt taatatttgt
    35521 ttaagatata ttattatatc ttctggagtt ctatcaaatt tgagttcaaa attttcatct
    35581 tcaaagtagg gaatataata taaaggtgtt ttgagagcag gtaatttatt atataattct
    35641 tcaagaatat cgatattttt aggggagtta aagaaaaagc atttacatac attcattaaa
    35701 tccacagcat ctgaaagtga gttatgttta atatctcctt ttacagaaaa aatttttttc
    35761 atattcagta aagatatttg cttagataag attctattat tgtatgtaat atgttgagat
    35821 ataaaaggtt gaatgtcaat catcatatta aataactcta agcatttacc tgtatattta
    35881 tacactctaa atgaagttag aaggccagct atatcaaaat caccccaatt atatattgta
    35941 acatcatcaa atttacaaaa ccatttataa aaatcatcca taacatataa aagattagga
    36001 gcattattga tatctagttg gttcaatttg gttaaatttt tacatttatt tgaaagtatt
    36061 ttattgtatt ttggcttaac taaagagtaa taattatcta ttgtattaaa ttcgttatca
    36121 actaaaattc caccaataga aattaattcc gcaccattat attcttttgg tttattttta
    36181 ttatcatcta gtatattaaa ttcaaagtct ataaataact tgtatttcat aaatctaaag
    36241 cacatcctca ggtaaattat ttattgagcc taagcatcat aagaatcaat agatataatg
    36301 actctaaaca tcaaaggttc attacaactt ttatttattt cataatttaa ttcaaataga
    36361 tcttttaaga tataatttat aagtattctt tcccaaccca tttttaaatt aactttagag
    36421 tctattaata tattttctat ctttttaaat atttctatat ttgctggtat tatactgagc
    36481 tcaatattac ttttaaacgg gttagactgt aaatctgtta taagtatatt ttttaattcc
    36541 tctgtaagtt cagaaattaa actatcacct atgtattttt ttatgatttc ctctctaatt
    36601 tcttttaaat ttagcaatat tagtacctgc tacttacata gtagcttttc ctttcctttt
    36661 aatactatta ttcatttttg aatcttattt agatatattt taagattaaa agtctttagc
    36721 tatataattt tttacccatt tttaacttat attaacatat tacaggctta tatctccacc
    36781 ctgtttacat tgaggatgga gtatattgcc tattttgata aaaatgatag gttgttattt
    36841 gcctattcct ttttctgata atttttctaa catatctttg gtcattttat ctaaatcata
    36901 actaaactta aagttccatt cttttactgc actactactg tctagagagt taggccaaga
    36961 atcagctata ctttgtctta cagggtctac atcatattct atcacaaaat caggaatata
    37021 tttttttata gaatcagcta tttcttcagg agaaaagctc atagcagtaa tattaaaagc
    37081 atttctatgg atgagtttat cagctggagc ttcgattaaa tccactattg attgaagtgc
    37141 atcaggcata tacatcatat ccatttttgt accttctgct atgtaagatt tatatctctt
    37201 attttttaat gcctcataat atatatcaac tgcataatct gtagttcctc caccaggagg
    37261 cgtaacataa gaaataagac ctggaaatct aacacctcta gtgtctactc caaattttga
    37321 gtgataataa tcacatagta attctccaga aactttagtc acaccataca tagtattagg
    37381 tctttgtaat gtatcttgag gagtcatatt ttttggagaa ttttcaccaa aagcagcaat
    37441 tgaactaggt gtaaaaaatt tacaatccaa ttctttggct atttcaagac catttattaa
    37501 tccattcata tttaagttcc aagcttctag aggtttactt tcagcaactg cagaaagtaa
    37561 agatgctaga tgaattatag tatctacatc atattttttt gcaatttcaa aaaaacgatt
    37621 cttatctgta acatctaata tctcaaatat accagattca catactggat taccttcttt
    37681 tactctcctt gaactagcga ttacattttg ttctccatac tcatttctaa gctttattgt
    37741 taattctgaa cctatttgtc ctaatgcacc tgttataagt atttttttca attttacaac
    37801 ctcctaaggg tttaatttat gtagtactac ttatttttat tttagcaaat cttttgttta
    37861 aatacaaaga attaaagata ataatatacg acttaattga atgaagtgca gtaagtgcgt
    37921 aaaaatttaa agctaatata taatggtcta ttgtataaca ataaaagagt agattaaatt
    37981 attatatata gattgtgtga ctaagtcaca gaaaataaag ctaatttaat atataataaa
    38041 agcatgtcaa gtaaagcttt aaattaaagt aactttatat aaaaagtaat ataaattgat
    38101 aaaattataa atttatttat agtgaatata ggttggattt tatagataca aaaatagtat
    38161 atatgatatg tagaccatta gcatgtttaa agtagcaaaa catataaaat aaaatttgaa
    38221 aggaagtata aaaatgacaa gaccatcaat atatcatagc caaggataca cttgtgcaga
    38281 ggcattaata aagtcttata atgaggaaca caacacagat ataccaatct caataggaag
    38341 tggtatgggg gttggaatga atgttggaag tgtttgtgga gctgtaaatg ctgctgttgt
    38401 tataataggg tatttaaatg ggcgaaatag taatttagat gaaaatatag caaggaagta
    38461 ttcaagagag ctattgaata gagtaagaaa taaatacagc tcagaaatat gtgtatctct
    38521 taaaaaaaat aaagtaactt gtgaagaaat aataaatttc acatatgatg ctctaaatga
    38581 tatgctaaaa aatcaaaaat aattctaaga aacaagtatt ttacattcga tagaatactt
    38641 gtttttttat gatattttta ataagtatta gtttattata atttttaaat caattttatt
    38701 atattttaat tgaaataatc tactttgaaa attactaact gacaaaagaa tatgattata
    38761 gtatagaaaa aatgtaaatt atttaatatt aagtgagagt atatgcttac ctatataaaa
    38821 tcgtataaat taatggctaa atttataaat tataaagaaa tatataggaa aataaaagga
    38881 ttaattagta taatataaag ttaaaaagta aaaatttata taatttattt ataaagtaaa
    38941 gaaaaaatag aaatttgtaa taaaataaaa agtttatgac ataatatggt ataattagta
    39001 aaaatataga gattggagga attgctttgt ttatagatga agaattagaa ggttatatat
    39061 taacatgtaa aatatctgaa gactttaaaa atatacctga atatagtgat gaagagtttt
    39121 atgttacagt ctataaagat gaaagttctg actctgggta ctatgcttta ttagaaaata
    39181 aagaagaaag agttgtatgg gatggagaag ttgttgccaa taatattttt aataaccttt
    39241 ggattgtagt aaataaggtt aaaactggat aatagtctaa ttatatagta tttgtaatat
    39301 tttaaatgaa tttttacata tttgagatga gtaaataaca aagattattc gatactggag
    39361 gagtaattca atggaatata gttatagtaa gatgaactta aaaaaagggg atattgtaga
    39421 ggtaaattta gagaaacaag ccaatgtaat attgttagac catataaatt atgtgaaatt
    39481 taaaaatcaa agaaattatg attactatgg tggatttgca aagaaaaatc catgtagaat
    39541 gagagttcct aatactggaa catggtatct agtagtaaat caagatggaa atagtggaat
    39601 agtaaacttt tcaatcaata caattcaaaa ttaattttag aatattggat attcttactt
    39661 tttgtacatt ttatatagtt aaaataaaat taataagcaa ttattataaa ataatgtggg
    39721 tgcctcaaaa tgaattttat aattcacgag acactctttt ttatatgaac tcaaatatac
    39781 tttatcattt caacaatgaa aaagaggcgt atctgtgttt tgagatagcc tcatatatca
    39841 tatatcatat atagaatttt aattattctt aactaaaatt ttttccatag gttatctgta
    39901 caattaaaat atttattgtt agcatacagc tccacctgta aggtgtaaaa gagcctctag
    39961 tatctcttct tttctttcca aaacttcatc tgataaaagc atttctataa atttatcagc
    40021 accgattcta tcgatagtta ttccaaaacg ttcacctgtg ttaccctgtt ctctaaataa
    40081 aagaattgct ttttcaatta aagtcataag ttcctctttt gaaaataatc tatcaatctg
    40141 tgttccagga cgaactgatt ttccccattt ccctcctata tagactttat aaccagattc
    40201 tttttcttca atactatcaa aattacaact ttctatacac ttaccacagt tattacatag
    40261 attactatct atttcaagtt tacctttatc tgttaattta gctgctttaa caggacagac
    40321 ctctacaaca gcacattttt tacaaccaac acaaagctct gaatcatagt caggtacacg
    40381 ttgaccaaca attccaagat cgtttaggtc aggtttaata cagttattag ggcatccacc
    40441 aacaccaatt ttgaacttat gaggtagttt tacatcatac caatttttgt aaaattcttc
    40501 gtgtatttca gcagcaagtg cctgtgtatc agctagacca tgaacacaaa cagtaccttt
    40561 acaagccaca acaggacgaa cccttgatcc agttccacct gttattagat tttcgctagc
    40621 aataaattca cttagagctt caatatcttc aaattttaca ccaggtaatt ctactgttag
    40681 tctagtagta aatgctaact gaccgtttcc gaatttttca gcagcttctg caattttttt
    40741 tgcttgtgat gcatttatta caccatttac agttattata cgtgctgcaa aatgttctcc
    40801 atccctgctt ggtagaaaac ctctaccttt tacttccttt ttttgttctg ctgtaacatt
    40861 actcatattt actcctccat taccttaaga tttggataaa atagtattcc accttcaaga
    40921 actttcgtat ttgtatagcc aaagcgtctt aagcgatttt gcgccatata gctattttta
    40981 cctttagcac atataagaag aattttttca tccttagcaa ggccttcaat ttctccatta
    41041 atttcaccaa caggaatata acgtaaacta ggaatagaag gagcttttga aacatcaagt
    41101 ttagtccaac tgtcaaaatc ctcaatttcg tcaagtaaaa cactatcaag ttctccatta
    41161 agtttatttt gtaaaacatt tactgccact acaaaagggt gaatagctgt tgaaaaaggt
    41221 ggtgcatatg caaggtccat actttctaat gaataaaggt cagcgcctaa agttattgca
    41281 gtagcagcga tatctactat tttatcaacc gctccaggtc ccataacttg aacacctaat
    41341 aattttctag tatttttttc agcaaccatt cttataataa aattagatgc acctggataa
    41401 taatgagctt tatcatcagt agctatggtt acagagcaaa cattataacc ttctttttca
    41461 gctatttctt tacttagacc tgtttttcct gcattgagct caggtaattt tactactgtt
    41521 gttccaagaa caccattgta agttttagat tttccagata tattttgtgc acaaattcta
    41581 ccctcatgat ttgcagatga ccccataggt gaccatgtag gtttatttgt taaagaattt
    41641 tttacaaaag cacagtctcc aactacgtat atatctttgt catttgtaag catatattca
    41701 tctgcaataa ttgtattatt aggggcaaat tctaaacctg tgtcttttag aaaacctgtg
    41761 ttaggacgga ttccaactga cataaccact aaatctgttt taatagctct atttttagta
    41821 cgaagttttt caactttatt ttcaccttca atacctacaa cctggtcacc tgtaaaaatc
    41881 attatgcctt tatcagccat atgattttca acgtattcag caaaatcagt atcaaatcca
    41941 ggcataacat gttcagccat atcaacaaca cttacacgta tacccattgc agaaagattt
    42001 tcagcaattt caagaccaat gaaacctcca ccaataacaa cagctctctt aataccgttt
    42061 tcgatagaat ctcttagttt tatagcatca tttggagtac gcataaagaa tactccaggt
    42121 aaatctattc caggtattgg tggttttatt gggtctgccc ctgtagcaat tacaagtttg
    42181 tcatagctta gattttcttt ttctcctgtt gaaagcgttt tcaaagttac ttgttttgca
    42241 tttctatcaa tagatgtaac ttcaactcca caacgaactt ctgctcctgt tagtttagaa
    42301 aaactttcag gtgtatttac gattaaagat gatttatctt caattatctt accaacgtaa
    42361 tatggaagac cacaacctgc ataagaaata tcatcacctt tatttagtat tgtaacagag
    42421 caattatcac ccatttcacg ttttattttt gcagcagttt ttgttccagc agcaactcca
    42481 cctataatta atactttcac aatatatcac actccaatct actttataac tctataataa
    42541 aattatactt cttgacaata tatttgtaaa atactaaaat attaataaaa tcataagcat
    42601 ttactaatgt ttgctaaggt tgtgataata tgacaattcg tagtcttgaa atctttgtta
    42661 aggttgctga atgtggtaaa atgagtgaag tagcaagaaa tatgtatatt acccagtcat
    42721 cagttagcca agctatttca gaaatagaaa aagagtatgg tgttaagcta tttgatagaa
    42781 tttcaaaaaa attatattta actgaggcag ggaaaaaact tcttggatat gggaggcatc
    42841 ttttagctgt aaatgaagaa atgaatgatt gtatgaagca ttgtgcaaaa aatatccgta
    42901 taagagttgg ggcaacagta actgttggta catgtgtaat aagtccaata atgttagaat
    42961 tatacaaggt aaatcctctt atagaacctg aagtatttgt agaagataca agactgattg
    43021 caaaaaaatt acttaatagt gaattagata ttgcgattgt agaaggaaaa attaagcacc
    43081 cagatattgt tacaaaaagc attattaatg ataatcttgt acttatatgt tcacacaagc
    43141 atgagtttta taaaagagac tctataaaag tttcagaact ttcaaatcaa ccattaatta
    43201 tgcgtgaatt gggaagtggt acaagagcac aattagaaaa gcaattaaaa gaattaaaaa
    43261 tcccaatgaa tattagatgg tcatgttata actctgaagc tatattaaga gcagttgtag
    43321 ataattttgg cattgcagtt atatccgaat tacttattga ggattattta aaaaagcatc
    43381 ttttgtgggc ttgtgatatt gaaggtatta atttacatag gacatttgat attgcatatc
    43441 atagaagcaa gttttttaca gaaaatattt cagcattttt tgatatttca gtagaatatg
    43501 ggaaaaaaca agcgagaaag aagagtagaa gtgtaaacag tttataatat atctaaataa
    43561 aaataagagt atatcaatat actcttattt ttatttagat atattagcct atattaacgc
    43621 caaaattttt acacaatcct gcaagtccat cctcaaatcc agaacctaaa gcattaaatt
    43681 tccactctcc attatgtcta tatagttctg ccacaactat tgctgtttct atgctaaaat
    43741 cttcacccaa ttcatattta ataagttcct cattagtttc ttcattatat attcttatat
    43801 atgaattttc aacttgtccg aaattttgtc ttcttgtaat tgcttcattt atagtaacac
    43861 taaatgatat tttagcaata ttttgaggta ttttagataa gtctacattt atttgttcat
    43921 catcaccatc accaacacct gttctattat cacccatata ttcaacagct ccagaagcgt
    43981 gttttaaatt attatagaat ataaagtctc catcattcgt tacttttcca tcagttccag
    44041 ttaaaaatgc agaggcatct aaatcgaaat caaagccacc atcatattta ttaatatccc
    44101 atcctagtcc tactattact ttttttagac cagggttact ttttgttaaa cttacttttt
    44161 gtccttttgc taaagttata cccatttaaa ccaactcctc attataaatt ttttattgta
    44221 attattactt atatgtatta attaattcac gaagctcttc attttgacca attcctaaag
    44281 cattaaattt ccattcttca tttctacgat aaatttctcc tgccaaaact gttactttac
    44341 cagaaaagtc ttcttgaaga ttatatttaa ataattcttg cttggaattt gaatcaatta
    44401 atcttataaa agagttgttc atttgaccaa aatcctggtc tcttttttta gctttgtata
    44461 tagaaactcc aaaaactatt ttatgtacat attcaggtat gtcttctaaa ttaacaatta
    44521 tttgttcatc atcaccttca ccttttccag ttaagttatc tccagtgtgt ataatagctt
    44581 tagaagggtg tttaagattt ccaaaataaa ccaagtcacc tctaacattc attttatctt
    44641 ggttagtcaa tgctattgca aatgcatcta ggtcataatt ttttttaccc aatttattca
    44701 tatcccatcc taagcctact actagatttt ttacaggatt attatctttt actaagctaa
    44761 ctctttgtcc tttttgtaaa ctaacactca ttttaagttc tcctttttat atttttagtt
    44821 ttattgatgg tatcaagtat aagaaccata ttagctatat tatatacgta tttaggctaa
    44881 gttggctata tttataaatt atttattata taactacatg aatattttat aatttaaaca
    44941 tattgacatt atatgcttta aattattttg tagttttata atatttaaat ttgtatttaa
    45001 ttgttataaa gtgaagtaag taataaagtt agactcaata attctaaaat ttctaagcat
    45061 actatctaaa tgagaacgga tttggaaata cttgtataat acaataattg atacat
//
LOCUS       DAFAZV010000030        44107 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFAZV010000030 DAFAZV010000000
VERSION     DAFAZV010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44107
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.030"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            27..878
                     /locus_tag="KOU88_002400"
     CDS             27..878
                     /locus_tag="KOU88_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase"
                     /protein_id="HBK3212273.1"
                     /translation="MKNIISAKELISKLEKNDNLVVIDCRFDLINRTYGIDSYKKGHI
                     KGSFILDIDKDLSSPTKEHGGKNPLQDPLILKEKLEKMGVDNDTTIVTYDDGDLNGAC
                     RLFFQLKHLGLKNVYVLDGGITSFVKEGGELEEKVNIPSCTGKEIRPNINNDLVVPME
                     YVKSKLYKKDTVIIDCRANERYQGLVEPAYSKAGHIPSAKNYFCKDLIKSDFENGSLK
                     DIEFLKKFFKDLNNYDEVILSCGSGISACVNSLALRELDIPHKIYIGSFSDWISYDDN
                     EIKTGQE"
     gene            complement(1011..2624)
                     /gene="ggt"
                     /locus_tag="KOU88_002401"
     CDS             complement(1011..2624)
                     /gene="ggt"
                     /locus_tag="KOU88_002401"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBK3212274.1"
                     /translation="MKFNAYQHKYSSIRNVVYAKNGAVATSTPLASQAGLEILKKGGN
                     AVDAAVATAATLAVVEPTSNGIGGDAYALVWIEEEKRLYGLNSSGFAPENMELKNYNN
                     MKEMPKYGFGAVTVPGIPAAWSELNKKYGKLSLMECLSPAINYAREGYVVSPNVAKVW
                     KKSYELYEKELIGEEFKPWFDTFSKDGKAPEAGDIFICEEQASTLEEIANTQAESFYR
                     GRLADKIDEYSKKFNGAIRKSDLECFYPTWVEPISTEYKGYKIFEIPPNGHGITVLMA
                     LNILKELELEGNIENVEDIHKIIESLKLAFADSKTYVTDIEHMKVKIQELLSQEYAKK
                     RSLLIDNKEALYPTAGEPYCGGTVYLCTADKDGNMVSYIQSNYINFGSGIVIPRTGIA
                     LHSRGNNFNLDPKHHNVVKPFKKPYHTIIPGFLGKEDKAIGPFGVMGAFMQPQGHIQV
                     LTNMIDFGLNPQEALDAPRWQWIKGKEIEVEPEMPKHIIDSLIEKGHEIKVIHDTVDM
                     GRGQIIFKTEQESYICGTESRCDGHIAVY"
     gene            complement(2849..4786)
                     /locus_tag="KOU88_002402"
     CDS             complement(2849..4786)
                     /locus_tag="KOU88_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212275.1"
                     /translation="MTLFRIAMQNVKNSFFNYLMYFISIVFSVFVFFSFKSIEYNEAL
                     SSLGEKTRMSINTSSIVIVVFVFLFIYYSNSFFFNRRRREVGTYSLLGMRKNQIGKIF
                     LYETFLMGIVAILIGIFLGLLFSKLMTMMLVKLMNEMIVVNMNLSIKALVQTLAVFLI
                     IFIVIGIRNTIVIRNKRIIELFNKYPEKYKFKKFIKLKCVLGVLLIAISYLMSISYFI
                     AENIMLSVFILVTIIPGTFLFFSSTMYMIIDAVKKRKSFYYKGQNLIAFSELGFKLKS
                     NSSILAVIAILIATSVTMLGFTISLYYDIDRNISENYKYSYTINLGNSYVNNEIDKLL
                     YKYKKDNKIIFDKTIELIDKDINIEMYYKNGNSYIEDRTSVDIIRESDFKKLRQYQNN
                     NYEELTSKESVYYVSDSYKKIFFKDFEIEKINLHIKDTNEYDINLFKVQKSILEPEIN
                     SQATFDLIVVKDDVFNQLKLHGNSRLIRLIDIKNEKRELDLTLKLKNIVSENMKFTYP
                     FNFTSSIESYNNLIKLSGLMLFIGIFLSVVFLLCTGSIILFKQLSNIYDDKERYIMLI
                     KLGANNKDIEKIISKQLKVIFLMPLVVGTVHNLFAMSIAQKFIPRSLLVPIIITLVIY
                     FIGYFIYYFLTLKYALNMIKE"
     gene            complement(4773..5540)
                     /locus_tag="KOU88_002403"
     CDS             complement(4773..5540)
                     /locus_tag="KOU88_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003722224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212276.1"
                     /translation="MEEILSVENIKKEYGRKGSKHEALRGITFKVYKGEFVGIMGSSG
                     AGKSTLLNIISTIDLPSSGDIYINGKNTIKMKQNELADFRRDNLGFVFQDSNLLDTLT
                     IKENIMLPLSLKNERVSVIENRIKEISKELNIESILDKYPGEVSGGQKQRGAVCRAIA
                     TKPSLVLADEPTGALDSKSARDLLNCLLKLNKDSNKTILMVTHDAISASFCNRILFIK
                     DGIIFTEIVKGESNREFYNKIVNTVSLIGGVNKNDFI"
     gene            5828..6502
                     /locus_tag="KOU88_002404"
     CDS             5828..6502
                     /locus_tag="KOU88_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3212277.1"
                     /translation="MFKIMVVEDDVSLKNIIAKCLTKWGHDVHQIENLENIIEEFKNY
                     NPELVLLDINLPFYDGFHWCNEIRKISKVPIIFISSRNSNMDVIMGVNLGADDYIQKP
                     FSVDVLVAKVNALLRRTYNFVDNNSNQIIHNGVTLDLSTATINYEDNTIELTKNEIKI
                     LHELMKYKGQIVSRNKLMKKLWDNDWFVDDNTLTVNVNRIRSKLNEIGLEDFIETKRG
                     LGYIIS"
     gene            6526..7530
                     /locus_tag="KOU88_002405"
     CDS             6526..7530
                     /locus_tag="KOU88_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3212278.1"
                     /translation="MSFKDFLKDKLGFLVYNFTFLIFTVSVIIFSPVDVFLTDTILYI
                     LVVNVVFLFLYLFISYIKKNKFLDKIKNDTFKINMNDIELARCKNEEKIYLNIIKNHQ
                     YQCNNIINNNIEKFEENKEILNMWVHDVKIPIAIIKLILEQNENLIDEKISDDIDSEI
                     FRIENSVEKILYLSRLEDFHKDFLIQEVNIEKIIRNIIKKYSKYFISKKIILDLNNLN
                     FKVLSDEKWLYFIFEQLLSNSLKYSSLGDNISIYCKRTKNYLQLRVEDTGCGIKKEDL
                     NRIFNKGFTGNNGRNNSKSTGLGLYLVKELCDKLGHKIDVDSEYNQYTKFTITFKCDL
                     "
     gene            7642..8871
                     /locus_tag="KOU88_002406"
     CDS             7642..8871
                     /locus_tag="KOU88_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBK3212279.1"
                     /translation="MSFLKKFKNKRFRNNSFKSNNFRNSSFGSSGFKSKNKGFKNNPF
                     KNKRFKIYAGIAVIILLILGVLAYVDSKNTELQANENFIETYTIPENEKIFINGMVVP
                     KQTKDFNISGDYELSDVNVTNGQKVNQGDLLFTAKNPTIISEIDSLKSQLSQYKKQKI
                     SLSDIAENKDAIASINAQITALNSQIASLDKKAYDRVTAPFDGTVYLNDQTGNPDQPV
                     SFMTIQGLEFYMKGQASEQDLPKMKIDQMVNILVFSTDQKLTGRISFISDKPSTPNTE
                     MGAQQNTLSYYDINIAFDNQEGLVNGFHLQASLEVANSSFKIPASCVLKDNKHSYVFK
                     DLDGILKKQIVDVASQNDDFAVVRGGLEQGDIIIKHPTKEMKEGDPVQGDGVTAGSNN
                     GDTTPNKKVEEVTMDVN"
     gene            8879..9553
                     /locus_tag="KOU88_002407"
     CDS             8879..9553
                     /locus_tag="KOU88_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212280.1"
                     /translation="MLIKLENIQKYYKVGKDELHVLKSLNLEIESGEFVMIMGKSGSG
                     KTTLLNILGFLDVFDEGRYIFDGTDVTNLSENERSVFRNINIGFVFQQFNLIETLNVY
                     QNVELPLIYNKALKKSNREEIVKDKLSSVGLLDKLKQKPLQLSGGQQQRVAIARCLAN
                     DPQIIFADEPTGALDSETSREIMELLTRLNKQGKTIIMVTHDQDLTKYATKVIRLKDG
                     VFTSEV"
     gene            9556..10788
                     /locus_tag="KOU88_002408"
     CDS             9556..10788
                     /locus_tag="KOU88_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212281.1"
                     /translation="MSLLKNSLANLKGHKLRVFVALLWIIIGITSVILVSSIGNGFQK
                     EIKKSVNNVNPNKTTISFESADNTGLTDDMSIFLKPFNAKDLEELSFVEGVERIAPSR
                     DGFNLDSVYSSQASFDKKTTYVDVGPVKKDSKINLICGRDFSLDDEKRKVILLTLQST
                     SEIFENPEDALGHGININGTIFEIIGVLDDSQQNQAGGFFGGYQDMQFTTSLVPKKAF
                     DTLMSQNSYSNEIYQLDLVSSKGYNVNEVANNVIAKLYEMHPGINGSYTTPDPTEQTA
                     YLESINSNVNKYVSIITVVAMFVGGIGVMNIMYVSVMERQREIGIRRAIGAKPRSILF
                     QFLVEAVFITVCGGILGTIVGFTATNYVSKYIGFEAIPSLNSLFYAIVATILTGVVFG
                     LIPAFKASKLDPIKAIYK"
     gene            complement(11074..12339)
                     /locus_tag="KOU88_002409"
     CDS             complement(11074..12339)
                     /locus_tag="KOU88_002409"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBK3212282.1"
                     /translation="MILIKNGRVIDPKSQRDENIDLIIKENKIYKIGKFDESDEYEKI
                     IDASGNVVAPGLVDVHVHFRDPGFTYKEDIESGAKSAARGGFTTVICMANTNPIVDNE
                     DTFNYVKEKSKNACINVLQAAAITKGFEGKELVDMEALKKAGVPGFTDDGLPLMDSNL
                     IMEAMIKAKELDVPLSFHEEDPSLVGNPGVNAGKVASELGLKGASSVAEDVMVARDCM
                     LALKTGAKVDIQHISSGVSVDMVRFAKYLGANVVAEASPHHFTLTEEDVLEFGTNAKM
                     NPPLRSKWDRDKIIEGLNDGTIEIIATDHAPHSKEEKDREFIKAPSGIIGLETSLALG
                     ITNLVHKNHLSMMQLIEKMSINPAKLYNLNIGFIEEGAVADIVIFNPEEEWTVESFVS
                     KADNSPFKGKSLYGKVNYTICNGEIVYNA"
     gene            complement(12392..13540)
                     /locus_tag="KOU88_002410"
     CDS             complement(12392..13540)
                     /locus_tag="KOU88_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBK3212283.1"
                     /translation="MKSVSVRSCKTYNYEEVKLSIEKNLEDIGGIDKFVKKGSKVLIK
                     PNLLMKKKPEEATTTHPMVVKVVCEKLLELNCDITIADSPGGPYNQSSLKSIYKASGI
                     EEVANELGIKLNYDVSDVKIHSEKAHVLKYMDIIKPIVDSDYIINLCKLKTHIMATFT
                     GGTKNLYGCIAGLKKAEIHYRFPTEELFCENVLLDICDYIKPTLTIMDGIVGMEGDGP
                     SAGTTREIGVLLASQNPYAIDVVACKIISLLPNRVATIRGAIKRGYIQEDFSDIEILG
                     EDIKDLIIKNYKIPNVSKDLRLFSVKLPKFLNEPISKLITPKPVVRFQDCIKCGKCKE
                     ACPASTIEIGTKGAIIDLSKCIRCYCCHELCPKKAIDVKRNFVFKYVK"
     gene            complement(13631..14176)
                     /locus_tag="KOU88_002411"
     CDS             complement(13631..14176)
                     /locus_tag="KOU88_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBK3212284.1"
                     /translation="MKKFVCTVCGYIHEGDAAPAQCPVCKVGADKFEEMKGEMVWADE
                     HRIGVAQGVDAEIIEGLRANFTGECTEVGMYLAMSRQADREGYPEVAEAYKRIAFEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKRAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRHFGK"
     gene            complement(14399..15343)
                     /locus_tag="KOU88_002412"
     CDS             complement(14399..15343)
                     /locus_tag="KOU88_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBK3212285.1"
                     /translation="MQKNKKEGALLKKYFGEIGLIFIAIIWGSGFVATQFALDGGLTP
                     LQIITLRFFLAAIIMNLLFFKQIRANMGKKLLKAGGILGIFLFLAFTVQTIGLMYTTP
                     SKNAFITAANVVIVPFIGFILYRRKLDKIGIISSLVALIGIGILSLEADFSINFGDFL
                     TLICSFGFAFHIFFTSEFAKDNNPMALTAIQFTVAFLMSVVVQTFAGQLKMEAELSGY
                     MGTMYLAVFSTTIGFLFQTICQKRVDGTRTAIILSTEAVFGTIFSIIILKELITAKLV
                     IGSILIFVAIITAETKLSFLKSKKVKLKDSEESSLESI"
     gene            15729..16610
                     /locus_tag="KOU88_002413"
     CDS             15729..16610
                     /locus_tag="KOU88_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase"
                     /protein_id="HBK3212286.1"
                     /translation="MVKKRKKKTVTLTILVVIVIGIFSMAWADMSRKKEMKETQERLK
                     AERLEKERIEKEKNEPIIGAKKEAVKEYGYDAKIVWDKLNKYDYSNNGEKIVFLTFDD
                     GPSTTNTPQVLDILKRHGVRGTFFIKGDSLERKGANEILKRTFDEGNAIAHHSYTHDY
                     KKLYPNRSLNLDTFVNELNKTDEAMKKVLGKNFSSNVVRCPGGYMSWKNMEPLGNYLK
                     EKNMASIDWNALNADAEGKKKNAQELFEHAKKSSEGKEMVVLLMHDTYGKQETVNALD
                     QIITYFKDNGYQFKILI"
     gene            complement(16671..17879)
                     /locus_tag="KOU88_002414"
     CDS             complement(16671..17879)
                     /locus_tag="KOU88_002414"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBK3212287.1"
                     /translation="MKSIDEQMRIIMKGVDDLIDEKELREKLIKSEKEGKPMIVKLGL
                     DPSAPDIHLGHTVVLRKMKQLQDLGHQIVIIIGDFTGKIGDPTGKSKARKALTTEQVL
                     ANAKTYEEQIFKVLDKEKTIVRFNSEWLAKLNFEDVIKLAATITVARMLEREDFKKRY
                     EGQMPISVHEFFYPLMQAYDSIALEADIELGGTDQRFNLLMGRSLQREFGMESQIVIM
                     MPLIEGLDGKEKMSKSLGNYIGIDEEAGIMYQKSMEIPDELIIKYYNLVTDVHPDEVN
                     KIESQLKEGSVNPRDIKMNLAREIVTLYHGEESAKEAEERFKSVFQKGQIPEDIQTIQ
                     VKEDGFDLIEVLVSNEIVKSKSEVRRLASQGGVKVNGEKVEDLSTIVKESELVVQIGK
                     KKFVKIELVK"
     misc_binding    complement(17952..18204)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(18356..19345)
                     /locus_tag="KOU88_002415"
     CDS             complement(18356..19345)
                     /locus_tag="KOU88_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2232 domain-containing protein"
                     /protein_id="HBK3212288.1"
                     /translation="MIYGGSVLNTTKKLTEAALLSSLFIVVTIIAVSTGFGYAIYLDF
                     IVPVFFCIICLKCDLKYTILSGITSLLIISLVLGNLGTAIWASQSVLLGIMCGYLINK
                     PTMVMDDLVYGSVFGVIVMVFIDIYASTLIGYSFMKEFQGYSKWIYFNGYTNFIYYLM
                     IALFPFGMVFCIYLLSLILGNKLHILDSNSLKKFLIFKNFRNLNQFLCCSKKAFYICV
                     SYLAIFEVLKLLNVKVDSVYLKTIFISITYISVYFIIRDSCMSLQNFIIAKFRKLLYA
                     RILFLIIILLLFFIFDVTVISLIIINAFLNKKINIRLSQSNIVNKQINLLIEK"
     gene            19497..19937
                     /locus_tag="KOU88_002416"
     CDS             19497..19937
                     /locus_tag="KOU88_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3212289.1"
                     /translation="MFKIKHFNDLSLDEFYEIAKSRYEVFACEQKIFSLNDYDDIDKS
                     SYHIFLKENGLICAYARIIPKEYSSYNDVSIGRVLVLSSHRRKGLAKQMMDCAIDFIK
                     VNLHENNITLSAQTYIKNLYLSCGFKEISEVYDEAGIEHIKMRL"
     gene            20263..20490
                     /locus_tag="KOU88_002417"
     CDS             20263..20490
                     /locus_tag="KOU88_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBK3212290.1"
                     /translation="MKNLNDIQVKKTVKVEDILSSGNLRERMLALGLTRGAVIDVVRK
                     GPKNNLTVYKIRGSKIALRQEESSLILVSDI"
     gene            20516..22636
                     /gene="feoB"
                     /locus_tag="KOU88_002418"
     CDS             20516..22636
                     /gene="feoB"
                     /locus_tag="KOU88_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBK3212291.1"
                     /translation="MGLTHNSTKMSSLKDMFDIDNKENQFVIALAGNPNTGKSTVFNH
                     LTGLRQHTGNWPGKTVATARGNFKYKNTEYALIDLPGTYSLFALSQEEIVARDFICFG
                     NPDAVIVVCDATCLERNLNLVFQVMELTDKVILCINLIDEARKKGITIDKKLLEDSLG
                     IPVILTAARNGSGMDELLDTLNDVSFDKYKLNNKPVRYNENIENVVKSIQPELDNIIP
                     GINSRWLGLRLIDGDESIFESMSNYIDKDSIDAINEVKKKIPDNINKQKIRDEFTKIN
                     YDYAKKLSDECCSNVAKKSTDREEKVDKILTSKIFGLPIMLLLLGTILWITIEGANYP
                     STLLSNLLLGFEPSISGILNSINCPSWLNDMLVLGLYRTLAWVISVMLPPMAIFFPLF
                     TLLEDFGYLPRVAFNLDHLFKKACAHGKQCLTMCMGFGCNAAGVIGCRIIDSPRERLI
                     AILTNNFVPCNGRFPTLIAISTIFFSSVITNSFVSSVATALCITLLIILGVIITLLVS
                     YTLSKTLLKGVPSTFTLELPPYRVPQIGRTLYTSIIDRTIFVLGRAVMVAIPAGVITW
                     IFANIYIGDLSILSHVANFLDPLAKLIGLDGFILLAFILGFPANEIVVPILLMAYLAT
                     GSMIELDSFSALGQVLREHGWTYLTALNVMLFSLLHWPCATTLLTIKKETGSLKWTAL
                     GFLMPTILAFVVCFLTTTVYNLFI"
     gene            complement(22769..23587)
                     /locus_tag="KOU88_002419"
     CDS             complement(22769..23587)
                     /locus_tag="KOU88_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3212292.1"
                     /translation="MEKQYFTTGEFAKLCGISKQTLIFYDKIGIFSPEYKDKNNYRYY
                     SVYQYDTLDILQSLREIGMSLEEIKEYIQNRTPQLCVKMLKEEEKKIREKIKKLRKIS
                     SKMQNRINITVEGISKMNSEEIYISKKFEEYLVLSSDLSNMSNSDFMMELIDFTNYCK
                     SKNLYQGYELGVIVSNENIKNGDYLSISSFYLKIDKKIKDKKLYVKPEGMYACIKHIG
                     KYEDSYKSYEKLKKYIYENEYKIIGNSYEESILDFFCESNEDNYMTEISIQVSR"
     gene            23795..24079
                     /locus_tag="KOU88_002420"
                     /pseudo
     CDS             23795..24079
                     /locus_tag="KOU88_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889354.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     repeat_region   24237..25983
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=24304..24332
                     /rpt_unit_seq="atttacattccatatagttaatataaaac"
     gene            complement(26642..28735)
                     /locus_tag="KOU88_002421"
     CDS             complement(26642..28735)
                     /locus_tag="KOU88_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3212293.1"
                     /translation="MNKHNFEVILNQLQINIYVTNIHTNEIIFMNKKMKEEYNILDPE
                     GKVCWQVLYPEKNSTCSFCKVLELLKNDKKGVLIKWYEKCNKLNRVFENYDSLITWQD
                     GTVVHMHQSIDIANSTSLNKPIKINEFHEISNNKEEKGVFNFSRDNFDYNSTLLYDAL
                     IRGTDEYIYICNMKTGVFRYSPSQVELFDLPGEIVENPLIYWKKIVHPEDWNRFYKSN
                     TEIGKNQMDYHTVEFRAKNRSGEYIWLRCRGQLMRDEFGEPSIFAGIMTQLGKQNKID
                     SLTQLLNYHEFMSVFEDKISNPMIEKLCIVLLNIDDFKNVNEMYDRDFGDNIIKTLAQ
                     SIQSILPDNAELYKLDGDEMGILVDNVEENEILTLYNQIQNMIIHLQLWRKYGLNITI
                     SAGCVIYPKHGDTVKELYKCASYSLQYAKEHGKNRLVFFSQEILKNKMYSLEMMRDLK
                     ASINDDFRGFSLRFQPQVDTESHKIIGVEVLLRWTNDKCKAISPLEFIPILEENDMIN
                     IVGAWVLRMALRTFRKWIDYYPFFKVSVNVSAVQILEDTFIEDIVKIIDDENFPYQNL
                     VLELTESHTVQNMSILQFKFKALQDLGIYIAMDDFGTGYSSLEVLKFSPIDIVKIDRV
                     FVKDILKSKFDATFIHFIVAICHDVGIKVCLEGVETQEEYDLVKQIKPDYIQGYLFGK
                     PQTATEIFDLLKLDN"
     gene            29379..30311
                     /locus_tag="KOU88_002422"
     CDS             29379..30311
                     /locus_tag="KOU88_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBK3212294.1"
                     /translation="MGFIGSGKVGTSLANYFLSKGYCVSGFYGRNQLSLLESTNLTKT
                     KIYSNLKDIIYENDILFITTSDDSIEIIDKKLSKFNLKHKYICHTSGSLKSSILFCSK
                     KAGALIYSIHPIFAFSNKNTNIKKMKDICFSIEGDNEQDDLVIQNFIDDLGNQFFIRD
                     KDTSSTYHLANVLVSNLVLSLLDIGVSYFIKLGLSEEESLKAISPLVKKNIENILDNG
                     FTKALTGPVSRGDITPIRKHLSVLDKKDEDIYKILSLNLLKIIALGNDNSLKGIKNIT
                     IENAIENLISKSEKYKEIYKLLGGKNDEKYHTDF"
     gene            30286..31113
                     /gene="panB"
                     /locus_tag="KOU88_002423"
     CDS             30286..31113
                     /gene="panB"
                     /locus_tag="KOU88_002423"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBK3212295.1"
                     /translation="MKNTIQTFKNAKYEGKKLSMLTAYDYSIAKIMDECDINGILIGD
                     SLGMVIKGEENTLSVTIDEIIYHTKAVKNGVKNALIVSDMPFLSYHVSIEDAVKNAGR
                     LIKEGGAHAVKLEGGSNVIKQIESIVNAQIPVMGHLGLTPQSVNSFGGFKVQGNTSET
                     ARQLIEDAKLIEKAGAFSIVLEGVPTKIAEMVTNSISIPTIGIGAGINCDGQILVYQD
                     MLGMFGDFVPKFVKQYANIGDIMKDSIKNYILEVNTGAFPQEKHSFSINESELEKLY"
     gene            31132..31980
                     /locus_tag="KOU88_002424"
     CDS             31132..31980
                     /locus_tag="KOU88_002424"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBK3212296.1"
                     /translation="MLVKEIKLLRNIIKDWRKHGYSIGLVTTMGFLHEGHQSLIKKAV
                     KENDKVVVSVFVNPTQFGPNEDFNSYPRDIDKDFKYCMDSGATVVFNPSPEEMYLKGN
                     CTTINVSGLTDFLCGAKRPVHFGGVCLVVSKFLNIVTPDKAYFGEKDAQQLAVIKRMV
                     KDLNIDTEIIGCPIIRENDGLAKSSRNTYLSEEERKSALILNKSLSLAKEELVKGNLN
                     PENIKELITAKINSEHLAKIDYVEIVDSETLQPVKQIEHSILVAIAVFIGKTRLIDNF
                     TFELNI"
     gene            32410..32592
                     /locus_tag="KOU88_002425"
     CDS             32410..32592
                     /locus_tag="KOU88_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212297.1"
                     /translation="MFKDKIDECVHIMTAYIASLKEYYSFIETQIGDFIKKYGEDVVE
                     LCLHRVMILLCECGLA"
     gene            33424..34338
                     /locus_tag="KOU88_002426"
     CDS             33424..34338
                     /locus_tag="KOU88_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2935 domain-containing protein"
                     /protein_id="HBK3212298.1"
                     /translation="MIDNQKYVILSLELHLFFSRIMKEHALFLEAGFTNKNYNLAMEA
                     DHYKKQFEDLLSYTVSASNGIIRPDILYSEELVTTLTSVAEQKTEEFTGIEINKNITT
                     RELNLQSGVDPQVGQDLVNYVAQLNSDAIRLLDGLINFKERVLDGVLSCTIFTSNYPL
                     LLEHIIHEANLYRSYVVDLENKIDIESKNAKEIELFWDHIMMEHALFMRGLLDPSEGE
                     LINTSNDFAIKFNELIEKTNEMTDSNIKNITEETLNETVEFKDFKEAGASGIEQCKIK
                     SIILPLLADHVLREANHYIRILESYKNM"
     gene            34728..35375
                     /locus_tag="KOU88_002427"
     CDS             34728..35375
                     /locus_tag="KOU88_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBK3212299.1"
                     /translation="MIRQTPLEKRYDKLGPHIVTALKKRYFDAYYCKTRNKALQQILD
                     LIPQNHVVSWGGSETLKEMGVQTAVREKGFKVIDRDLAKTPEERTEIMRQALLCDTFL
                     MSSNAISEDGQLFNIDGNGNRVAAMIFGPKNVIVVAGMNKIVKNIDDAIQRTRTIASP
                     AVVQRFQDVNTPCYINGSCIDCTSPESICAYMVTTRISRPAKKIKVILVGENLGL"
     gene            complement(35542..36111)
                     /locus_tag="KOU88_002428"
     CDS             complement(35542..36111)
                     /locus_tag="KOU88_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK3212300.1"
                     /translation="MKKFIICIIMFAISVLVLAGCTNDNKIKNEVDSMFNSIKTQDAD
                     TVDKYFPKSGLGNLIYEDKEGFKMYSKNMTWEISDIKNNKDKVTVDLKINNTDMVSIL
                     KKNPPKLGEMMPNPTMKDIDSAKKKEFNITLELVKSGDNYVCKVNQESAMKLLNVITG
                     GGIDYLADYNKDYYKQLDEEQKNYENKNS"
     gene            complement(36116..37015)
                     /locus_tag="KOU88_002429"
     CDS             complement(36116..37015)
                     /locus_tag="KOU88_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3212301.1"
                     /translation="MKLLSKVNNNIRLITQVAFTALTNGYVNGFLEGTIYGGESKKLC
                     VPGLNCYSCPGALGACPIGSLQAVLSSREYKFSFYVVGFLMAFGAFFGRFVCGWLCPF
                     GLVQDLLHKVPFPVKIKKVYGDKYLKYLKYIVLIMFVIILPVAIVNVAGGGNPWFCKW
                     ICPSGTLLGGIPLILGNENLRESIGFLFSWKLSILLLILLMSIITYRPFCKYICPLGA
                     IYGFFNPISIYRFKIDKDKCTNCTACQTKCKLDIPIYKDVNSPDCIRCGECIKVCPQN
                     AITTTFSKDKKENNICAKKYRGI"
     gene            complement(37026..37175)
                     /locus_tag="KOU88_002430"
     CDS             complement(37026..37175)
                     /locus_tag="KOU88_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212302.1"
                     /translation="MSNFIKDNKKGISIIAISIIFIALGTYRGETNTVLTKAIMICLE
                     CIGIG"
     gene            complement(37168..37752)
                     /locus_tag="KOU88_002431"
     CDS             complement(37168..37752)
                     /locus_tag="KOU88_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBK3212303.1"
                     /translation="MKRFFIVVLGCIFVLGVISGCSKKESKPVEKNKNNSEWFSNLDT
                     EDVDGNKVTKEIFSNKELTLINVWTTWCGPCVGEMPELEALSKEYESNNSNVAIKGLV
                     VEVDKTDMRTGLSNEEKNLVKDIMKKSDATYQQLTVSEELKKTDFKRVMEFPTTYFVD
                     KKGNFVGEKVVGANSKEDWKKIIDERLKMVKANE"
     gene            38141..39466
                     /gene="cdeA"
                     /locus_tag="KOU88_002432"
     CDS             38141..39466
                     /gene="cdeA"
                     /locus_tag="KOU88_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter CdeA"
                     /protein_id="HBK3212304.1"
                     /translation="MENLFTRKFTTFEFLKFVSPAIISMIFISLYTIIDGIFVSTLVG
                     SDALASINIVLPIINLVCGFGIMMATGGGAIVSIRMGENRQDEANSTFSFIVLFSLIV
                     GILFTVISYFFIKEISILLGATDKLLPYCITYGKVMILCTPFYILKFIFEYFARTDGN
                     SKFSLFLSVIGGVTNIILDYVFIKYFGMGLLGAAVATAIGIILTCVLGIIYFLSNKST
                     LKLRKPKTDFRLIRDTMINGSSEMVTELSTGITTFLFNVVALKLAGENGLAALTIVLY
                     AHFLMTSVYLGFAAGVSPLISYNFGAENSDKLKETFKHSLKFIFVSSLLVFIIALVFA
                     PFIVRVFVSPDNTVFKLALQGLKIFAFAFLFVGINIFASGFFTAFHNGKISAIISFSR
                     AFVFIIIGIIILPPMLNMTGLWLTVPFAEVITIFISILFIKKYKGRYKY"
     gene            complement(39561..40355)
                     /locus_tag="KOU88_002433"
     CDS             complement(39561..40355)
                     /locus_tag="KOU88_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212305.1"
                     /translation="MNELKPYIKFFNKNTKLYIIIFMIVGIVMNILPVFILKIFGEAS
                     KTNLSTIVNPILTYITILLFVYGVNIANKDFSGALSIRADRKSCIKAIVIDLIILSFV
                     ISILGIVLIFLSKLFIEIITGYSIELSVLLKRDMIWTSISALIDPSTSSMPLTYLNYF
                     VQICINEICIGFIGVLLGAFTYRVRKVTSITILIGLPILMVIYIVNFATKNMHKMLLY
                     LEKIIYSFQNPFILFGTKVGIIVICIIFIILLLRKAPIKEYANDLL"
     gene            complement(40356..41231)
                     /locus_tag="KOU88_002434"
     CDS             complement(40356..41231)
                     /locus_tag="KOU88_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212306.1"
                     /translation="MSSSIKIENLSHSFKKQNIFNNMSLNFEKNKIYGLLGKNGAGKT
                     TLLNIMVNQLIQNEGEIEILGKNPKEDIKVLEEVCIVREKEFYSSDFKVGQIFEFSSS
                     FYKSYDKGLEKELCKYFDLNTKKKYKQLSRGMKTILSNIIGICSNSAITIFDEPTIGL
                     DAVNRQEFYNIILDSYIKNPRTIIISTHLIDEIDDLLEHVIILNEGKIIIDEEIDVIK
                     QKAHYITGNKEELEKLECIKNIKPKKAFGNAVAYFYYGDFSENDEKILKNSNIDVGYI
                     GLQDMFVNMTKKEEL"
     gene            complement(41235..41603)
                     /locus_tag="KOU88_002435"
     CDS             complement(41235..41603)
                     /locus_tag="KOU88_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3212307.1"
                     /translation="MKLVLNNEEPIFIQIARAIEDEILSNGIKEEEQVPSTTELSKLY
                     KINPATVLKGINILVDKNILYKKRGIGMFVSDGAKTIIKEARKENFKHNFVKNLLQEA
                     NKLEINREELVDIIINFKED"
     gene            complement(41786..42445)
                     /gene="deoC"
                     /locus_tag="KOU88_002436"
     CDS             complement(41786..42445)
                     /gene="deoC"
                     /locus_tag="KOU88_002436"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBK3212308.1"
                     /translation="MKHILKTVDHTILKATTTWEDIKILCDEAVDMSVASVCIPPSYV
                     KRASEYLKGKIKICTVIGFPLGYQTTATKVFEAKDAIENGADEVDMVVNISDIKNKDY
                     DNIGKEIKEIKKAIGDKVLKVIIETCYLDEDEKIKMCEIVTMSGSDFIKTSTGMGTGG
                     ATLEDIKLMKEHVGKNVKIKAAGGVKSISDAEKFIEAGAERLGTSSICKILKNEDTTD
                     Y"
     gene            complement(42481..43668)
                     /gene="murJ"
                     /locus_tag="KOU88_002437"
     CDS             complement(42481..43668)
                     /gene="murJ"
                     /locus_tag="KOU88_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBK3212309.1"
                     /translation="MKQEPCDFSHGRFRTGIIFIGITSVMSAFLQIKENFIVVGFGSI
                     PYNIVIIISIMLSTIFGPYILPIGAVVAMVVQLLFYMFFVKKTNYKYLYYLNFKDDSL
                     IKLLALLSPVFIGVAVNQVNSLVDTTLASTLVKGSIPALTYADRLNGFVTGTFTASIV
                     SVMYPMLSKLSAENNQKKFTSSVKSSINMIIISMIPISVASIFFATPVVRIIFERGAF
                     DARATQMTATALIFYAVGMTAFGLRDILGKVFYSLQDTKTPMVNGIISVGVNIVLDLV
                     LIKPMAHGGLALATSSSSIACILLLFLNLKRKVGYFGQDKIIKATLKSVVASLIMGVL
                     SYFTYKFIFGILGVGTFNEFVSLAISVIVGGGIYTLLMIIFKVEEVDMILNIAKRKLH
                     LKK"
     gene            complement(43745..>44107)
                     /locus_tag="KOU88_002438"
     CDS             complement(43745..>44107)
                     /locus_tag="KOU88_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3212310.1"
                     /translation="QKLTTKLIKENDIICIEDLQVKNIIRNRKLSRLISDVSWSEFIR
                     QLEYKANWHGRQIVKVDKFFASSQICNKCGYKNEEVKNLNIREWICPSCNETHDRDIN
                     ASINILKEGLRLITIQNK"
BASE COUNT        15711 a         6587 c         5335 g        16474 t
ORIGIN      
        1 taatataaac acaggaggta cattctttga aaaacattat ttcagcaaaa gaacttatat
       61 caaaactaga aaaaaatgat aatctagttg taatagattg tagatttgat cttatcaata
      121 gaacttatgg tattgattct tataaaaaag gacacatcaa aggcagtttt atcttagata
      181 tagacaagga tttatcatct cctacaaaag aacatggtgg taaaaatcct ttacaagacc
      241 ctttaatact aaaagaaaaa ttagaaaaaa tgggtgttga taatgacact acgattgtaa
      301 cttatgatga tggagattta aatggagctt gcagattatt tttccaatta aaacatttgg
      361 ggcttaaaaa tgtctatgta ctagatgggg gaataacatc tttcgtaaag gaaggtggag
      421 aattggaaga gaaagtgaat ataccaagtt gtacaggtaa ggaaattaga ccaaatataa
      481 acaatgattt agttgttcca atggaatatg ttaagtctaa attatacaaa aaagatactg
      541 taataataga ttgtcgtgct aatgagagat accagggttt agttgaacct gcttactcaa
      601 aagctggtca tataccaagt gcaaaaaatt atttttgtaa ggatttaata aaaagtgact
      661 ttgaaaatgg ctcacttaaa gatatagaat ttttaaaaaa attctttaaa gatttaaata
      721 attatgatga agtaatttta tcttgtggtt cagggatatc tgcttgtgtt aacagtcttg
      781 ctcttagaga actggatata cctcacaaga tttatattgg tagctttagt gactggatta
      841 gttatgatga caatgaaatc aaaactggtc aagaataagg ctcataatct atataaaatc
      901 agcatatgat agcttaagtt ttgtaaaggc gtcagtcatt gtagactttc gcctttactt
      961 attatttcat atactcttta aatttattat atatatttta gttgataata ttaataaact
     1021 gcaatatgac catcacatct tgattccgtc ccacaaatat aactttcctg ttctgtttta
     1081 aatattattt gacctcgtcc catgtcaaca gtatcatgaa ttacttttat ttcatgaccc
     1141 ttttcaatta atgaatctat tatatgcttt ggcatctctg gttcaacttc tatttctttt
     1201 ccttttatcc actgccatct tggagcatct agcgcctctt gtggatttaa tccaaaatca
     1261 atcatatttg ttaacacttg aatatgtcct tgtggttgca taaaagctcc cattacacca
     1321 aatggaccta ttgctttatc ttctttacct aaaaatccag gtattatagt atgataaggt
     1381 tttttaaatg gttttactac attgtggtgt ttagggtcta aattaaaatt atttcctcta
     1441 ctatgtaaag caatcccagt tcttggtatc acaattcctg aaccaaaatt tatgtaattg
     1501 ctctgtatat atgaaaccat atttccatcc ttatctgcag tacaaaggta tactgtacca
     1561 ccacaatatg gctctcctgc agttggatac aaagcctctt tattgtcaat caataaactt
     1621 ctttttttgg catactcttg gcttagtaat tcctgaatct ttaccttcat atgctctata
     1681 tcagttacat atgttttaga atctgcaaaa gctaatttta aactctctat aattttatgt
     1741 atgtcttcta cattttctat atttccttct aattccaatt cttttaatat gttaagtgcc
     1801 attaaaactg ttattccatg accatttggt gggatttcaa atattttata tcccttatat
     1861 tctgtactta taggttctac ccatgttgga taaaaacact ctaagtcact ctttcttata
     1921 gccccattaa attttttaga atattcatct attttatcag caagtcttcc tctataaaag
     1981 ctttcagcct gagtatttgc tatctcttct aatgtacttg cctgttcttc acatataaat
     2041 atatctccag cctctggagc tttaccatct ttagaaaatg tatcaaacca tggtttgaac
     2101 tcttctccaa taagttcttt ttcatagagt tcatatgatt ttttccatac cttagctaca
     2161 ttaggagata ctacgtatcc ctctcttgca tagtttatcg ctggagataa gcattccatt
     2221 aagctaagtt taccatattt tttatttaat tctgaccaag ctgctggtat tccaggtaca
     2281 gttactgctc caaacccata ttttggcatt tctttcatat tattataatt ttttaattcc
     2341 atattttctg gagcaaagcc actagaattt aaaccataca atcgtttttc ttcctctatc
     2401 caaacaaggg catatgcatc tcctccaatc ccattgcttg taggttctac tactgctaat
     2461 gtggcggctg ttgcaactgc tgcatcaaca gcatttccac ccttttttag tatttcaagt
     2521 ccagcttgag atgctaatgg tgttgatgtt gcaactgctc catttttagc atacacgaca
     2581 tttcttattg atgagtattt atgttggtag gcattaaact tcataaattt cagctcctcg
     2641 tcatttttta tttgatattc tgcttagatt tattatataa catcaagtaa tgtaactgat
     2701 acaaaatgat ataaaatata gactttttcc taactttaat tttattttta aataaatatc
     2761 ttaaactcaa ttctagtatt ttctatctgt acttaaataa gttattttat tcaaaacata
     2821 tatctaattc ttttaactta aaaataattt attcttttat catgtttaga gcatatttta
     2881 aagttaaaaa ataatatata aaatatccta taaaataaat gactagagtt atgataattg
     2941 gtacaagtaa tgaccttggt ataaactttt gtgctataga catagcaaat aaattatgaa
     3001 ctgtacctac aactaatggc attaaaaata taacttttaa ctgttttgat attattttct
     3061 caatatcttt attatttgct ccaagtttta ttaacataat atatctttcc ttatcatcat
     3121 atatatttga taattgttta aataagatta tactacctgt acataaaaga aatactacag
     3181 acaaaaatat gcctataaac agcattagac cacttaattt tatcaagtta ttataacttt
     3241 caatacttga tgtaaaatta aaaggataag taaatttcat attttcactt actatatttt
     3301 ttaattttaa agtcaaatcc agttctcttt tttcattttt tatatcaatt aatcttatta
     3361 atctagaatt tccatgtaat tttaactgat taaatacgtc atcttttact acaattaaat
     3421 caaacgtagc ttgtgaattt atttctggct ccaagatgct tttttgtact ttaaacagat
     3481 ttatatcata ctcatttgta tctttaatat gcaagtttat tttttcaatc tcaaagtctt
     3541 taaaaaatat ttttttgtat gaatcagaaa catagtacac agattccttt gaagttaatt
     3601 cttcataatt gttattctga tattgtctta attttttaaa atcactttct ctaataatat
     3661 ctacagacgt tctatcttct atataactat ttccattttt ataatacatt tcaatattta
     3721 tatctttgtc tataagttct attgttttat caaagattat cttattatct tttttatatt
     3781 tatataataa tttgtcaatt tcgttattta cataagaatt tcctaaattt atggtataac
     3841 tgtatttata attttcactt atgttcctat ctatatcgta ataaagtgat atggtaaacc
     3901 ctagcatagt tacacttgta gctattaata ttgctattac agccaatata ctactattgc
     3961 tctttaattt aaatccaagt tcagaaaatg caattaaatt ctgtccctta taataaaaac
     4021 tttttctctt cttaacagca tcaataatca tatacatcgt tgatgaaaaa aataaaaaag
     4081 ttccaggtat tattgtaact aatataaaaa ctgaaagcat aatattttca gcaataaaat
     4141 aactaattga cattaaataa gaaatagcta ttaataaaac accaagtaca cattttaact
     4201 ttataaattt tttaaactta tacttttctg gatatttatt aaataactct ataattctct
     4261 tatttctgat aactatagta tttcttattc caataactat gaatattatt aaaaataccg
     4321 ctagtgtctg aactaaggcc tttatactta agttcatatt tactactatc atttcattca
     4381 ttaattttac aagcatcata gtcataagct ttgaaaataa cagtcctaaa aatataccta
     4441 ttagtattgc aactataccc atcaaaaaag tttcatataa aaatattttt cctatctgat
     4501 ttttcctcat tccaagtaaa ctataagttc ctacttctcg cctacgtcta ttgaaaaaaa
     4561 atgagtttga ataatatata aataaaaata caaataccac tattacaatt gaacttgtat
     4621 taatactcat cctagttttc tctccaagtg aactcaacgc ttcattatac tctatagatt
     4681 taaaactaaa aaatacaaat acactaaata caattgaaat aaagtacatt aaataattaa
     4741 aaaaactatt ctttacattt tgcattgcaa ttctaaataa agtcattttt attaactcct
     4801 ccaattaagg aaactgtatt tactatttta ttatagaact ctctgttact ttctcccttt
     4861 acaatttctg tgaatattat tccatccttt ataaagagta ttctattgca aaaactcgca
     4921 cttatagcat catgagttac catcaatatt gttttattgc tgtctttgtt taattttaat
     4981 agacaattca acaaatccct agcagattta gaatctaatg ctcctgtagg ctcatctgca
     5041 agtactaatg atggttttgt tgctatagct ctacatacag ctcctctttg cttttgtcca
     5101 ccagaaactt cgccagggta tttatctaat atagattcta tatttaattc ttttgaaatc
     5161 tcttttattc tattttctat tactgatact ctttcatttt ttaaagaaag aggcaacatt
     5221 atattttctt ttattgtaag tgtatccaaa agattagaat cttgaaatac aaagcctaga
     5281 ttatcacgtc taaaatctgc caattcattt tgcttcattt taatagtatt ctttccattt
     5341 atataaatat ctcctgatga aggtaaatct attgtagaaa taatatttaa aagtgttgat
     5401 ttaccagcac cggaagaccc cataatacca acaaattctc ctttataaac cttgaaagtt
     5461 attcctctta gagcttcatg ttttgaacct tttcttccat actccttttt tatattttca
     5521 acagataata tttcttccat agttaataat cacctttcgt cacaattagt tatttatcaa
     5581 ttctcacaaa tatattatat atattaaaat ggcttttaaa catttaatta tattaattta
     5641 aggttacatt ttcgtaagta ttaattatat ttcttcaaat ttattgcaat tatgtttaaa
     5701 atataattta tcaagtaaaa tatagttata ttaatataat tattttaggt aataaggtag
     5761 aaatatttta atttatcaag tagaatatag ttatgttaat ataactattt tgaattagga
     5821 ggtaagaatg tttaaaataa tggtagttga agatgacgtc tcattgaaaa atatcatagc
     5881 aaagtgtctt actaaatggg gacatgatgt tcatcaaata gaaaatcttg aaaatataat
     5941 agaagagttc aaaaactata acccagaatt agttttattg gacataaacc ttccatttta
     6001 tgatggtttt cattggtgta atgaaataag aaaaatttca aaagttccta taatttttat
     6061 ttcttcaaga aattctaata tggatgtaat aatgggtgta aatttaggtg cagatgatta
     6121 tatacaaaaa cctttttctg tagatgtctt agtagctaaa gttaatgccc ttttaagaag
     6181 aacttataat tttgttgata ataactcaaa tcagattatt cacaatggtg ttactttaga
     6241 tttatcaact gcaacaataa actatgaaga taatactatt gagctaacaa aaaatgaaat
     6301 caaaattctc catgagctta tgaaatataa ggggcagata gtaagtagga ataaactcat
     6361 gaaaaaatta tgggataatg attggtttgt agatgataat acattaactg tcaatgtaaa
     6421 tagaatacgc tcaaaattaa atgaaattgg tttagaagat tttatagaaa caaaaagagg
     6481 attgggttat ataatcagtt aaaacaattc taagtaggtg aatttatgag ctttaaagat
     6541 tttctcaagg ataaactagg ttttttagta tacaatttta ctttcttaat ttttacagta
     6601 tcagttatta tattttctcc tgtagatgtt tttctgactg atactatttt atatatatta
     6661 gttgtaaatg ttgtgttttt atttttatat ctatttatta gctacatcaa gaagaacaaa
     6721 tttttagata agataaaaaa tgatacattc aaaattaata tgaatgatat agaattagct
     6781 agatgtaaaa atgaagaaaa aatatacttg aacattatta aaaatcatca atatcaatgt
     6841 aataacataa taaataataa tatcgagaaa tttgaagaaa acaaagagat tttaaatatg
     6901 tgggtacatg atgtaaagat acctatagct ataataaaac tcattcttga acaaaatgaa
     6961 aatttaattg atgaaaaaat ttcagatgac atagatagtg aaatatttag aattgaaaac
     7021 tccgttgaaa aaattttata tttatcaaga ctcgaagatt ttcataagga ttttttaatt
     7081 caagaggtaa atattgaaaa aatcattaga aatattataa aaaaatactc aaaatatttt
     7141 atttcaaaaa aaattatttt agacttaaat aatttgaatt ttaaggtttt atctgatgaa
     7201 aaatggctat acttcatatt cgagcaatta ttgagtaatt ccctaaaata ctcctcatta
     7261 ggagataata tatctatcta ttgcaaaaga accaaaaatt atttacaatt aagagtggaa
     7321 gatactggtt gtggtataaa aaaggaagat ttaaatcgaa tattcaataa gggatttaca
     7381 ggtaataatg gaagaaacaa ttctaaatct acaggtcttg ggctttattt agtaaaagaa
     7441 ctttgtgata agcttggtca taaaattgat gtagattcag agtacaacca atatacaaaa
     7501 tttactatta cattcaaatg tgatttatag tatcttatta ttgatagttt attttcatta
     7561 acttatattc aacttcttat agtaattcta tatgtacatc ccagtatata attaagtagt
     7621 ttttataaaa aggaggaaga catgtctttt ctaaaaaaat ttaaaaataa aagatttaga
     7681 aataacagtt ttaaaagtaa caactttaga aatagcagtt ttggaagtag tggcttcaag
     7741 tctaaaaata aaggttttaa aaacaatccc tttaaaaata agagattcaa aatatatgca
     7801 ggaatagcag taatcatact tttaattcta ggagttcttg cttatgttga ttcgaaaaac
     7861 actgaattac aagctaatga aaattttatc gaaacatata ctattcctga aaatgaaaaa
     7921 atatttataa atgggatggt tgttcctaag caaactaagg acttcaatat atctggagat
     7981 tatgagttaa gtgatgttaa tgttacaaat ggtcaaaaag taaatcaagg agaccttctt
     8041 tttactgcta aaaatccaac tataatatca gaaatagata gtttaaaatc acaacttagt
     8101 caatacaaaa aacaaaaaat atcactttct gatattgctg aaaataaaga tgctattgct
     8161 tctataaatg cacagataac tgctttaaac tctcagatag cttctctgga taaaaaagct
     8221 tatgacagag ttactgctcc ttttgatggc acagtatact tgaatgacca aactggaaat
     8281 ccagaccaac cagtttcatt tatgactatt caaggtctag agttttatat gaaaggacaa
     8341 gcaagtgaac aagatttacc taaaatgaag attgaccaaa tggtcaatat actagttttt
     8401 tcaactgacc aaaagcttac tggtagaata agttttatat ctgataaacc atctactcca
     8461 aatactgaaa tgggagctca gcagaataca ctatcttatt atgatataaa catagcattt
     8521 gataatcaag aaggattagt aaatggattc catcttcaag catcacttga agtagctaat
     8581 tcaagcttta aaataccagc atcttgtgta cttaaagaca acaaacactc atatgtattt
     8641 aaggatttag atggtatatt gaaaaagcaa attgtagatg tagcaagtca aaatgatgat
     8701 tttgctgtag ttagaggcgg tcttgaacaa ggcgatataa taataaaaca ccctactaaa
     8761 gaaatgaaag aaggagaccc agttcaaggc gatggcgtaa ctgctggttc taataatgga
     8821 gatactactc caaacaaaaa agtagaagaa gttactatgg atgtgaatta atttacatat
     8881 gttaattaaa ttagaaaata ttcaaaaata ttacaaagta gggaaagatg aattacatgt
     8941 tttaaaatcc ttaaatttag aaattgaatc tggagaattt gtcatgataa tgggtaagtc
     9001 tggtagtggt aaaactactt tacttaatat cttaggtttt ctagatgtat ttgatgaagg
     9061 aagatatata tttgatggaa cagatgtaac taatttgagt gaaaatgaac gttctgtttt
     9121 tagaaatatt aatattggat ttgttttcca acaatttaat ttaatagaaa ctctaaatgt
     9181 atatcaaaat gtagagttgc ctctaattta caataaagca ctaaaaaaat ctaatagaga
     9241 agaaattgtt aaagataaat taagttctgt tgggcttttg gacaagctta agcagaaacc
     9301 acttcaatta tctggtggtc aacaacagcg tgtagccatt gcacgttgcc tagcaaatga
     9361 ccctcagata atctttgctg atgaaccgac tggggcatta gatagtgaaa ctagcagaga
     9421 aattatggag cttttaacaa ggctcaacaa acaaggtaag actataataa tggttacaca
     9481 tgatcaagat ttaactaagt atgcaactaa ggttatacga cttaaagatg gtgtgtttac
     9541 ttcggaggtg taatcatgag tttattaaaa aattctttgg ccaatttaaa aggtcacaag
     9601 cttcgtgtat ttgtagcttt actctggatt ataataggaa taacttcagt aatacttgtt
     9661 agttctatag gtaatggatt tcaaaaagaa attaagaaat ctgtaaacaa tgtaaaccct
     9721 aataaaacta ctatttcgtt tgaatcagcc gataacacag gtcttactga tgatatgagt
     9781 atttttttaa aaccctttaa tgcaaaagat ttagaagaat tatcatttgt tgaaggagta
     9841 gaaagaatag ctccttcaag agatgggttt aaccttgatt cagtttactc ttcacaagca
     9901 tcttttgata aaaaaactac gtatgttgat gttggaccag taaaaaaaga ttctaaaata
     9961 aatttaattt gtggtagaga tttttcttta gatgatgaaa aaagaaaagt aattttactt
    10021 acattacaaa gtacaagtga aatttttgaa aatccagaag atgccttagg tcatggtatc
    10081 aacataaatg gaactatatt tgaaataata ggggtattag atgattctca gcaaaaccaa
    10141 gctggaggat tctttggagg ttaccaagat atgcaattta ctacttccct agtacctaaa
    10201 aaggcttttg acactttaat gagtcaaaat tcttattcaa atgaaattta ccagttagac
    10261 ttagtttctt ctaaaggcta taatgtaaat gaagttgcaa acaatgttat agctaaatta
    10321 tatgagatgc accctggtat caatggttct tatactacac cagacccaac tgaacagaca
    10381 gcttatcttg aaagcattaa ttccaatgta aacaaatatg tatctataat aactgtagtt
    10441 gcaatgtttg ttggtggtat tggtgtaatg aatataatgt atgtatctgt tatggaaaga
    10501 caaagagaaa ttggtataag acgtgctatt ggagcaaaac ctaggtctat attatttcaa
    10561 tttttagttg aagctgtttt tataacagta tgtggtggaa ttttaggaac tatagttgga
    10621 tttactgcta ctaactatgt ttctaaatat ataggttttg aagctatacc tagcttaaat
    10681 agcttatttt atgcaattgt agctactata ttgactggag ttgtatttgg tctgattcca
    10741 gcctttaaag cctctaaact agaccctata aaggcaattt ataagtagaa attgtataaa
    10801 gattttcgat ttttagatta gtttatataa aacatactta aatatataac gcactattat
    10861 atatgataga ttaggaactt aatctttcca aatataatag tgcgttcttt cataaaaagg
    10921 attctcttcc ttactatatc taaattacca agatgttatg ttctaattgt tcaaactaat
    10981 acttccaatt ttgattaatc aatctcattc tcctaatata caatctttta ctttcaatca
    11041 ttgtacactc cgccttaaaa aaataatctt aaattaggcg ttatatacaa tctccccatt
    11101 acatattgta taattaacct ttccatataa agatttacct ttaaatggtg aattatcagc
    11161 tttagaaaca aagctttcaa ctgtccattc ttcttctgga ttgaatataa caatgtctgc
    11221 tacagcccct tcttctataa atccaatatt taaattgtac aactttgcag gatttataga
    11281 cattttttct attaactgca tcatactaag atgattttta tgcaccaaat ttgttattcc
    11341 aagagctaaa gaagtttcaa gcccaataat tccacttgga gcttttataa actctctatc
    11401 tttttcttct ttactatgag gtgcatggtc cgttgctatt atttcaatag taccatcatt
    11461 taatccctct ataatcttat ctctgtccca tttacttctt agaggtggat tcatttttgc
    11521 atttgttcca aactccaata catcttcctc agtcaatgta aagtgatgtg gtgaagcttc
    11581 tgcaactaca tttgcaccta agtattttgc aaatctaacc atatcaacag atacacctga
    11641 acttatatgt tgtatatcaa ctttagcacc agtctttagt gccaacatac aatctctggc
    11701 taccataaca tcttctgcta cacttgatgc accttttaat cctagttctg aagctacctt
    11761 tcctgcattt acacctggat ttccaactaa agaagggtct tcttcatgaa aactaagtgg
    11821 tacatccaac tcttttgcct taatcattgc ctccataatt agattgctat ccattaaagg
    11881 taatccatca tcagtaaacc ctggtacccc agctttttta agagcttcca tatcaactaa
    11941 ctctttacct tcaaaacctt tagttatagc tgctgcttgt aaaacattta tacatgcatt
    12001 ttttgacttt tctttaacat aattaaaagt atcttcatta tctacaatag gattagtatt
    12061 tgccatacat ataacagttg taaatccacc tctagcagca gatttagctc cactttctat
    12121 atcttcttta tatgtaaacc cagggtctct aaagtgtaca tgtacatcca ctaaacctgg
    12181 agcaactaca ttaccactag catctattat tttttcatat tcatcacttt catcaaactt
    12241 gcctatttta taaattttat tttcttttat aattaagtca atattctcat ctctttgact
    12301 tttagggtct attactctac catttttaat taaaatcata ttatttctcc tttatatttt
    12361 taatttatat agactcatat aatattatac attattttac atacttaaat acaaaattac
    12421 gtttgacatc aatagccttt ttaggacaaa gttcatggca acagtaacat cttatacatt
    12481 tacttaagtc tataatagca cccttagtcc ctatctctat agtggatgca ggacaagctt
    12541 ccttgcattt tccacatttt atgcaatctt gaaatcttac cacaggcttt ggtgttataa
    12601 gctttgaaat aggttcattt aaaaattttg gtagctttac agaaaacaat cttaaatcct
    12661 tacttacatt tggaatcttg taatttttta taattaaatc ttttatatct tcacctaaaa
    12721 tttcaatatc tgaaaaatct tcttgtatat atcctctctt aatagcacct ctaattgtag
    12781 caactctatt tggaagtaaa cttataatct tacatgcaac aacatctata gcatatggat
    12841 tttgtgatgc taataaaact cctatttctc gagtagtacc agctgaaggt ccatcacctt
    12901 ccatacctac tataccatcc ataattgtca atgttggttt tatataatca caaatatcta
    12961 aaagtacatt ttcgcaaaac aactcttctg taggaaatct ataatgtatc tctgcttttt
    13021 tcaatccagc tatgcatcca tataagtttt ttgtaccacc agtaaaagtt gccattatat
    13081 gagtctttaa tttacaaaga tttattatat aatctgaatc tactattggt ttaataatat
    13141 ccatatattt tagaacatgt gctttttcac tatgtatctt aacatctgaa acatcataat
    13201 ttaacttaat gcccagttca tttgctactt cttcaattcc agatgcctta taaatgctct
    13261 taagagaact ttgattatat ggaccaccag ggctatctgc tattgtaata tcacaattta
    13321 actctaaaag tttttcacat acaactttta caaccatagg atgtgtagtt gtagcttctt
    13381 caggcttttt tttcatcaat aaatttggtt ttataagtac tttgcttcct tttttaacaa
    13441 acttatctat accaccaata tcctctaaat ttttttcaat agataacttt acttcttcat
    13501 aattgtaagt tttacaactc ctaacagata ccgacttcat attatctcca tccttctatc
    13561 acaacagttt atttgtataa tttaaaaaag gagaaaccaa agtttctcct tttaatctat
    13621 gttttaatta ttattttcca aaatgtctgt ttaataatcc taagaatgct ttaccatgtc
    13681 tagcttcgtc tttacacatt tcatgtactg tatcatgtat agcatctaat cctaattctt
    13741 tagctctctt agctaatttt aattttccat cagttgcacc atactcagca tcaactctaa
    13801 ctcttaagtt ttcttttgta tctgcaacca caacttctcc aagaagttct gcaaatttag
    13861 cagcatgttc agcctcttca aaagctattc tcttatacgc ttcagctact tctggataac
    13921 cttctctatc agcttgtcta ctcattgcta aatacattcc tacttctgta cactcaccag
    13981 taaagttagc tcttaatcct tcgattattt ctgcatctac accttgagct actcctattc
    14041 tatgttcatc agcccaaacc atttcgcctt tcatttcttc aaatttatca gctccaactt
    14101 tacacactgg acattgtgct ggtgcagcat ctccttcatg tatatatcca catactgtac
    14161 aaacaaattt tttcataatt aatttcctcc caattttata taattaaatt tttattttta
    14221 agtttaataa cttgctacaa gaatatatat accccagact ttatagctta aacactaaaa
    14281 ataaaattta tttcctaatt aattttatca ctttgaaaca ccagtatcaa ccaagttttg
    14341 atgtcaaatt tctacataat acataattta tttgattaat taggaaatag ttgtcatatt
    14401 aaatactttc taatgaagac tcctctgaat ctttaagttt cacttttttg ctctttaaaa
    14461 aagataattt agtttctgca gttatgattg caacaaatat caagatacta ccaataacca
    14521 attttgctgt aataagttcc tttagaatta ttatagaaaa tattgtacca aatacagcct
    14581 ctgtggataa tattatagct gttctagttc catcaactct tttttgacat atagtctgaa
    14641 ataaaaatcc aattgtagta ctaaatacag ctagatacat agttcccatg taaccagata
    14701 attcagcttc catctttaat tgacctgcaa atgtttgaac tacaacagac attaaaaacg
    14761 ctactgtaaa ttgaatagct gtcaatgcca ttgggttgtt atcttttgca aactcacttg
    14821 taaagaatat atgaaatgca aatccgaatg aacatataag tgttagaaaa tctccaaaat
    14881 taatagagaa atcagcttct aaagaaagta tcccaattcc tataagagct accaaactac
    14941 ttattattcc tattttatca agttttcttc tataaagtat aaatcctatg aacggaacta
    15001 ttacaacatt agctgctgtt ataaacgcat ttttagatgg tgtagtgtac ataagtccaa
    15061 tagtttgtac tgtgaatgct agaaataaaa atattcctaa aatccctcct gcttttaata
    15121 attttttacc catattggca cgaatctgtt taaaaaacag taaattcata attatagctg
    15181 ccaagaaaaa tcttaaagtt atgatttgta gaggtgtaag cccaccgtct aatgcaaatt
    15241 gggttgctac aaagccactt ccccatataa ttgctataaa tattagtcct atttctccaa
    15301 agtatttttt caataaagcc ccctcctttt tatttttttg caaaattata aaccccctaa
    15361 acagcaagag agtttttcta taagcattac tataaattaa tatagtaaat tttttcagta
    15421 ttttaaatct aaatttacat acattttgag ctcaaattta tatccactat ttaacagtaa
    15481 tatattaatc attttttgta aacacctttt taataaattt ttatattttt tatatttttt
    15541 tacctatact aaattttttt atagatattt ttaatatata tgatacttta atattatgca
    15601 aataatgtca tataagttac actttagtta tcttagttac aactttgtcg gtttactttt
    15661 tctactttct tcgatataat tataatatat ttttgataca attcgacaaa agggggaatg
    15721 ctgtaattat ggtaaaaaaa agaaaaaaga aaactgttac acttactata cttgttgtaa
    15781 tagttattgg tattttttct atggcatggg cggacatgtc tagaaaaaaa gaaatgaaag
    15841 aaactcaaga aagacttaaa gctgaaagat tagaaaaaga aagaattgaa aaagaaaaaa
    15901 atgaacctat tattggtgca aaaaaagaag ctgtaaaaga atatggatat gacgcaaaaa
    15961 tagtttggga caaacttaac aaatacgact attcaaacaa tggagaaaag atagtctttc
    16021 ttacatttga tgatgggcca tctactacta atactccaca agttctagat atcttgaaaa
    16081 gacatggtgt tagaggaact ttctttatta agggtgattc tcttgaaaga aaaggagcta
    16141 atgaaatttt aaaaagaaca tttgacgaag gaaatgcaat agcccatcac tcttatactc
    16201 atgactataa aaaactatat cctaacagaa gcctaaatct cgatacattc gtaaatgaac
    16261 ttaacaaaac tgatgaagct atgaaaaaag tcttaggaaa gaatttttcc tcaaatgtag
    16321 ttagatgccc aggcgggtat atgtcatgga aaaatatgga acctctagga aactacttaa
    16381 aagagaaaaa catggcatca attgattgga acgctttaaa tgctgatgca gaaggtaaaa
    16441 agaaaaatgc acaagaatta tttgaacatg caaagaaatc ttctgaaggc aaagaaatgg
    16501 ttgttctttt aatgcatgat acttatggaa aacaagaaac agtaaatgca ttggaccaaa
    16561 ttataacata ttttaaagac aatggttatc aatttaaaat tttaatataa taaaaaagca
    16621 agtttattga atgtacattt tatactcaat agacttgctt ttactttact ctattttact
    16681 agctcgattt ttacaaattt tttctttcct atttgaacaa ctaattcact ctcttttaca
    16741 atagtgctta aatcctctac tttttcacca tttaccttta ctccaccttg agaagctaat
    16801 cttctaactt cactcttact cttaacaatc tcattagaaa ctagtacttc gattaagtca
    16861 aatccatctt ccttaacttg aattgtttgt atatcttcag gtatttgacc tttttggaat
    16921 acagatttaa atctttcttc agcttcttta gcagattctt ctccatggta taatgttact
    16981 atttctcttg ctaagttcat ctttatatct cttggattta ctgaaccctc tttcaactga
    17041 gattctattt tattaacttc atcaggatga acatctgtca ctaaattgta gtatttaatt
    17101 ataagttcat caggaatttc catagatttt tggtacatta ttcccgcttc ttcatctatt
    17161 ccaatatagt tacctaaact cttactcatt ttttctttac catctaatcc ttctattaaa
    17221 ggcatcatta ttactatttg agactccata ccaaattctc tttgtaatga tcttcccatt
    17281 agtaaattga atctttggtc agttccacca agttctatat cagcttctaa tgctatagag
    17341 tcatatgctt gcattaatgg gtagaagaac tcatgtactg atattggcat ttgtccttca
    17401 tatctctttt taaaatcttc tctttctaac attctcgcaa cagtaatagt tgctgctaat
    17461 tttattacat cttcaaaatt taacttagct aaccactcgc tattaaatct tacaatagtt
    17521 ttttctttat ctaaaacttt gaaaatttgt tcttcataag tttttgcatt tgcaagaact
    17581 tgctctgttg ttaaagcttt tctagcttta gattttccag ttgggtctcc aatttttcct
    17641 gtaaaatctc caattattat tactatttga tgacctaaat cttgtaattg tttcatcttt
    17701 ctaagaacta ctgtatgccc taaatgtata tctggagcac ttgggtctag acccaatttt
    17761 actatcatag gctttccttc tttttctgat ttaataagct tttcccttaa ctctttctca
    17821 tctattaaat catctacacc tttcataatt attcgcattt gctcgtctat cgatttcatt
    17881 tttcattcct cctaaaatat ttatataatc tataattttt atttttataa taaaaaaagc
    17941 tttcatcctc ttaaaaggac gaaagcattg cttacgtgtt accaccttag ttcatcaata
    18001 tctcacgata ttaatctctt agagtacaat tacatatact cgtgtactat aacgtgtact
    18061 aatccgatat ctcttaatgg ttgttatctt tcagagatag tgctctgaga tgtattcaaa
    18121 ctaaatcaat ttattccatt tcaccaaact ggaactctct gttaaataaa atatagccct
    18181 acttcttctc ttcatagcat ttatatattc agattatttc atcaattaca agaaattttt
    18241 cttaacttac tcataatata ttattatttt tatattttgt caaccttttt tattattata
    18301 tacatgtttt tttacattat actacttttt tatatttttt accaataccc aaaatttatt
    18361 tttcaatcaa aagatttatt tgtttattga ctatattact ctgactcaat cttatattta
    18421 ttttcttatt taaaaatgcg tttataatta ttaaactaat aactgttaca tcaaatataa
    18481 aaaacagcaa taaaattatt atcaaaaata aaattctagc atataataat tttctaaact
    18541 tagctattat aaagttttgt agtgacatac atgagtctct aatgataaaa tagacactta
    18601 tataggttat tgatataaag attgttttta aataaacaga atcaacttta acattcaaca
    18661 gttttagaac ttcaaaaatg gctagataag aaacacatat gtaaaaagct ttttttgagc
    18721 aacataaaaa ttggtttaaa tttctaaagt tcttaaatat taaaaatttt tttaaagaat
    18781 tagaatctaa aatatgcaat ttattcccta aaattaaact taataaatat atgcaaaaca
    18841 ccataccaaa aggaaacaat gctatcatta aataataaat aaaatttgta tacccattaa
    18901 aataaatcca tttgctatat ccttgaaatt ctttcataaa actataacct attaatgttg
    18961 aagcatatat atcaatgaaa accattacaa taaccccaaa tactgaacca tatactaaat
    19021 catccataac cattgtaggc ttatttatta gatagccaca cattatacca agtaatacac
    19081 tctgacttgc ccaaatagca gttcctagat ttccaagtac cagagaaatt attaaaagcg
    19141 aagtaattcc agataaaatg gtatacttta aatcacattt caagcagatt atacaaaaaa
    19201 atactggcac tataaaatct aagtaaatag catatccaaa tccagtactc acagctataa
    19261 ttgttactac tatgaataaa gatgacaata aagctgcttc agttaatttt ttagtagtat
    19321 tcaaaacact gcctccataa atcataaatt ttctaactaa agttttgttt ttaatatagt
    19381 atatcacttt ttaaaaatat ttttaataaa tataaatttt aataaaggta tttatgttaa
    19441 aaatggtata atgtatctta atattcagtt ttttaagatg ctaggaggta attactatgt
    19501 ttaaaattaa acactttaat gatttgagtt tagatgaatt ttatgaaata gcaaaatcaa
    19561 gatatgaggt atttgcttgt gaacagaaga tattttcatt aaacgattat gatgatatag
    19621 ataaaagctc ttatcacata tttttaaaag aaaatggatt gatttgtgct tacgctagaa
    19681 taattcctaa agaatacagc tcttataatg atgtttccat tggtagagtt ttagttcttt
    19741 ctagtcatag aagaaaagga ttagcaaaac aaatgatgga ttgtgctata gattttataa
    19801 aagttaactt acacgaaaat aatataacct tatcagcaca aacttatata aagaaccttt
    19861 acttatcttg tggttttaaa gaaatctcag aagtatacga cgaagcaggt attgaacata
    19921 ttaaaatgag attatagtgt tgacaagcta atattgttaa tatataattt aagtataaat
    19981 taaatattga attgatattt aggtatttga aaatacctta catagagtca gaaggctttt
    20041 gctttctgac ttttttatta tcaaaattca ataattatat ggattcaaag tgttaatttt
    20101 tattctatat tctactttcc ccaaaagtaa gaattatacc caactttgta tgataggcat
    20161 cttgcctatc tttttttgta aaagtaacaa ggtaataata taatgcatag tttaaaataa
    20221 gaagattagc ccaggctaaa tttcaagcat ggaggtgcta ttatgaaaaa ccttaacgat
    20281 attcaagtga aaaaaactgt caaagttgaa gatatattat ctagtggtaa tttaagagaa
    20341 agaatgttag cgcttggtct tactagagga gctgttatag atgtagttag aaaaggtcca
    20401 aaaaataatt taactgtcta taaaatcaga ggtagcaaga tagctctacg acaagaagaa
    20461 agtagcttaa tattagtttc tgacatttaa aaatttctag caggaggata ttaatatggg
    20521 gttgacacat aactcaacta aaatgagttc tttaaaagac atgtttgata tagacaataa
    20581 ggaaaaccag tttgtaattg cattggctgg caatccaaat acaggtaaaa gtactgtatt
    20641 taatcatctt acagggctta gacagcatac tggaaactgg ccaggaaaaa ctgtagctac
    20701 agctcgtggt aattttaaat ataaaaatac cgaatatgca ttaatagatt taccaggaac
    20761 atattcttta tttgccttat cacaagaaga aattgtagct cgtgatttta tatgttttgg
    20821 taatccagat gcagtaatag tagtatgtga tgctacatgt cttgaaagaa atttaaattt
    20881 agtatttcaa gtgatggaac ttacagataa agttattttg tgtattaatt taatagatga
    20941 agctagaaaa aaaggcatta ctattgataa aaaactttta gaggattctc ttggtattcc
    21001 agttatttta actgctgcaa gaaatggctc tggtatggat gaactattgg atactttaaa
    21061 tgatgtatct tttgacaaat ataaattaaa taataaacct gttagataca atgaaaatat
    21121 agagaatgtg gtaaaatcaa ttcaaccaga attggataat attataccag gtataaattc
    21181 taggtggttg ggacttagac ttattgatgg cgatgaaagt atatttgaat ctatgagtaa
    21241 ttatatagac aaagattcta tagatgctat taatgaagta aagaaaaaga ttccagacaa
    21301 tataaataaa cagaaaataa gagatgaatt tactaaaatc aactatgatt atgctaaaaa
    21361 actgagtgat gagtgttgtt ctaatgttgc taaaaaatca actgatagag aagaaaaagt
    21421 agataaaata ttaacatcta aaatatttgg gcttccaata atgctcttat tattaggtac
    21481 tatattgtgg attactatag aaggagctaa ctatccatcc actttattat ctaatttatt
    21541 actcggattt gagccaagta tttcgggtat attaaatagt attaattgtc catcatggtt
    21601 aaatgatatg ttggttttag gattatacag aacattagca tgggtaatct ctgtaatgct
    21661 acctcctatg gcaatatttt ttccattatt taccttactt gaggattttg gatatttgcc
    21721 aagagttgca tttaacttag accacctatt taaaaaagct tgtgcacatg gaaaacagtg
    21781 tttgactatg tgtatgggat ttggatgtaa tgcagctgga gttattggtt gtaggataat
    21841 tgactctcca agggaaagac ttatagctat acttacaaac aactttgttc cttgtaatgg
    21901 tcgttttcct actttgatag ctatatctac aatatttttt agctcagtta taaccaactc
    21961 tttcgtatca agtgtagcaa ctgcactttg cataacttta ctgataattc taggtgttat
    22021 aataacattg ttggtttctt acactctttc taagacgcta ttaaaaggag ttccgtctac
    22081 atttacatta gaacttcctc cttatagagt tcctcaaata ggaagaactt tatatacctc
    22141 tataatagat agaacaatat ttgttttagg aagggctgta atggtagcca tacctgctgg
    22201 tgtcataact tggatatttg caaatatata tataggagat ttaagtatat tatcacatgt
    22261 tgcaaacttt ttagaccctt tagctaaatt aattggtctt gatggtttta tattacttgc
    22321 ttttattctt ggattcccag caaatgagat agttgtacct atacttttaa tggcttacct
    22381 agcaactggt tctatgatag aattagatag ctttagtgct ttaggtcaag ttcttagaga
    22441 acatggatgg acttatttga cagctttaaa tgttatgctg ttcagtttac tgcattggcc
    22501 ttgtgcaaca acacttttaa caataaaaaa agaaactggt agtttaaaat ggactgcctt
    22561 aggattctta atgcctacta tacttgcttt tgttgtttgt tttttaacaa ctacagttta
    22621 caatttattt atataattag tattaactga cagtagacat atattagaga aactatttaa
    22681 aaatttatat actttattat aaagcataga gatatattca atgataagta aaattactta
    22741 acatttgaat atatctctat tttaattctt atctggatac ttggattgaa atttcagtca
    22801 tataattatc ttcattactt tcacaaaaaa agtcaagtat actctcctca tacgaatttc
    22861 caataatttt atattcattt tcatatatat attttttcaa tttttcgtaa gatttatatg
    22921 aatcctcata ttttccaata tgttttatgc aagcatacat tccttctggc tttacatata
    22981 gctttttatc ctttattttt ttatctatct tcaaataaaa acttgatata cttaaatagt
    23041 ccccattttt tatattttca ttacttacta ttactcccaa ctcatatcct tgatacaaat
    23101 ttttcgattt acaataattg gtaaaatcta ttaattccat cataaaatca ctattactca
    23161 tattactcaa atcgcttgat agaactaaat attcttcaaa ctttttggat atataaattt
    23221 cttcactatt cattttagaa attccttcaa ctgttatatt tattctattt tgcatcttag
    23281 aacttatctt tcttagtttt tttatttttt ctcttatctt tttttcttct tctttaagca
    23341 ttttcacaca aagctgggga gttctatttt gtatatactc ttttatttcc tctaaactca
    23401 ttcctatttc tcttaatgat tgtaatatat caagtgtatc atattgataa actgagtaat
    23461 atctataatt atttttatct ttatattcag gagaaaaaat acctattttg tcatagaaaa
    23521 ttaatgtctg cttagatata ccacacaatt tagcaaattc acctgttgta aaatactgtt
    23581 tttccaaggg ttatacactc cttttctttt tgttgtctat atagttacta tattctttat
    23641 tatttactaa atcaagtagt tattatttta gaaaatcaat atggttttga ttttaaagct
    23701 taaatatcag ttagatgtca gttataaata ttttacccat tcccatcata aaaaaagata
    23761 taccctctta acttttggat ggaatattat atttatgctt gttagagtga aaattgtaat
    23821 aggtgctaca ataagatatt taattaaaca taaagttaat tattgtaata aaaaatcttt
    23881 agataaatta gagttaaagt atggaaatat agatagagaa aaagctgtta aactagaaat
    23941 attttattaa tatttaatag aacttgaata tatagaaatg agtttattaa taggaagatt
    24001 agatactgca ataacatcat tagcattagt atctattata acaatagcat catattattt
    24061 aatcagaaaa aatgtgtaat tatgtaagct atttataata aaacactgat aaaattaata
    24121 ataaaaaggt aataggattt ctatactacc ttttggtttt tataatatag tgtaatttta
    24181 ttatattttt gtatgctaat ataactagat aatcataaga taacacatta aaagaaaatt
    24241 atattctgta tagttagtat aaaacgtaag taatataaat ttatgtaaag caacaaaaga
    24301 tggatttaca ttccatatag ttaatataaa acgcttatga ccttccctat atccctggtt
    24361 cttatgatat ttacattcca tatagttaat ataaaacaaa gatttgattt ttgtttctgt
    24421 ttatttattt ataatttaca ttccatataa ttaatataaa acttaataaa gacatatttg
    24481 ttattttcaa atcattttga tttacattcc atatagttaa tataaaacct cttataagta
    24541 tgactcctat acaaaaattt acgatattta cattccatat agttaatata aaacacacag
    24601 ttgatgaaac agaaaaagag gttcttttgg aatttacatt ccatatagtt aatataaaac
    24661 aatgatataa aagacgtttt tggcgaaaaa gttatagatt tacattccat atagttaata
    24721 taaaacgaaa tctttattca gcgattacaa gaggagatat tgcatttaca ttccatatag
    24781 ttaatataaa actaatatac tttgttacta ttccatcttt aaatccacaa tttacattcc
    24841 atatagttaa tataaaacca aaattaaaat tttttagtga cctattcttt aaaaaattta
    24901 cattccatat agttaatata aaaccagaat aataaaagaa gcgaaaatat attagactcg
    24961 tatttacatt ccatatagtt aatataaaac aagttgtaga ggaactaggt tatccgattt
    25021 ttttgcaatt tacattccat atagttaata taaaacacga cagcagaaaa ccaaattgat
    25081 ttatacgtgt gggaatttac attccatata gttaatataa aaccggattt taaacctcct
    25141 tttgatgttc ctgttagtaa atttacattc catatagtta atataaaact tgcctgttcg
    25201 agaagtagtt aatactttcg tgattattta cattccatat agttaatata aaaccacata
    25261 atacttctca aattcctaat aattgttatt tatttacatt ccatatagtt aatataaaac
    25321 cttgacgaaa ctaaactagt catacccgtt caaaacattt acattccata tagttaatat
    25381 aaaacttcta gtcctgtatc tataaaaaca atctcgtcta aatttacatt ccatatagtt
    25441 aatataaaac aaaagcaaaa agccactctc gtgcaaagag tgacttacat ttacattcca
    25501 tatagttaat ataaaacaat atgagcttat gaaagagctt gaaatgaata tttaatttac
    25561 attccatata gttaatataa aacaaaaatc aatacctata ataaaaaagt tttgagttta
    25621 tttacattcc atatagttaa tataaaacgc aaaatcaaaa atttgactta ataacaccat
    25681 taattaattt acattccata tagttaatat aaaacggtga tacttttggg taagcttctt
    25741 tcacctagtt ggatttacat tccatatagt taatataaaa cctttaactg tatatacttt
    25801 gttgtcatag gcagtaccat ttacattcca tatagttaat ataaaacgaa gtgttggaga
    25861 atataaaaat ttatatttaa aagttcattt acattccata tagttaatat aaaactaaac
    25921 catcttttaa ctttccgctt cttttgctga ccctatttac attccatata gttaatataa
    25981 aaccccaaaa taaacttagt attttcaaca cttacacgta tacaactctc ttaaatttgc
    26041 agtgaacgag caatagtgca attgataacg cttatcatgc actctcaacg ccttatattt
    26101 caactgttac gccaaatttt ttcacaaata tcgctcactg caaaattcct ataattttat
    26161 tatatcataa atatattact tttgaatatt gataccaatt tataccataa taaaagcaaa
    26221 aaaacgtaat ctatctacat tagatttaaa ttctataact taaagttttt tacataatat
    26281 ttatgcttgt ttaatcaatc taatatatca ttcttgtata ttgcttttaa tagtcttttt
    26341 tcttaaataa atatctatct gaacaagcat agtttaatta aaaacttttg tattccctta
    26401 aaactgtatc tacctcttat tattttattt atgatatatt atttttaatc taaaaataga
    26461 tatctatttt tattatggtt atcccttttt aaaatacttt aatcatatac tattcccaat
    26521 ttaacatcca ttgaaatgct attttcttat attgcaattt ataattgata tatcttcaat
    26581 ataataattt aatgtatttt tgattttaaa gcttttcagt gatattattg ataaattaga
    26641 attaattatc tagctttaaa aggtcaaaga tttctgttgc tgtctgcggt tttccaaata
    26701 aatatccttg tatgtaatct ggctttattt gtttaactaa atcatactct tcttgtgttt
    26761 ctacaccttc taaacatact tttattccta cgtcatgaca aattgcaaca ataaaatgta
    26821 taaatgtagc atcaaactta ctctttaata tatctttaac aaatactcta tcaattttca
    26881 ctatatctat tggagaaaat tttaaaactt ctagagacga gtatcccgta ccaaaatcat
    26941 ccatagcaat ataaattcct aaatcttgta aagccttaaa tttaaactgt aaaatactca
    27001 tattttgtac tgtatgactt tctgtcaatt ctaaaacaag attttgataa ggaaaatttt
    27061 catcatctat aatttttact atatcttcaa taaatgtgtc ttctaatatt tgaacagctg
    27121 aaacgtttac actcacttta aaaaaaggat agtaatcaat ccatttccta aaagtacgta
    27181 atgccattcg aagcacccaa gcccctacaa tatttatcat atcattttct tctaatattg
    27241 gaataaattc caaaggagaa attgctttgc atttgtcatt agtccacctt aaaagaactt
    27301 ctacacctat tattttatga ctttctgtat ctacttgtgg ctggaatcga agactaaacc
    27361 ccctaaaatc atcattaatt gatgccttta aatcccgcat catttctaat gaatacattt
    27421 tattttttaa tatttcttgg gagaaaaaaa caagcctgtt tttaccatgc tctttcgcat
    27481 attgtaaaga gtaactagca cacttataaa gttcttttac tgtatctcca tgttttggat
    27541 atattacaca accagcagaa attgttatat ttaatccata ttttctccat agttgaaggt
    27601 gtataatcat attctgtatt tgattatata gagttagaat ttcattttct tcaacattat
    27661 caacaagaat acccatttcg tccccatcaa gtttataaag ttcagcatta tctggtaaaa
    27721 tagattgtat agactgtgct agtgttttta ttatattatc tccaaaatcc ctatcataca
    27781 tctcattaac atttttaaaa tcgtcaatat ttaataatac tatgcataat ttttcaatca
    27841 taggatttga aattttatct tcaaatacac tcataaattc atgataattc agtaactgtg
    27901 tcaatgaatc aatcttattt tgtttaccta attgcgtcat tattcctgca aaaatacttg
    27961 gttctccaaa ttcatcacgc attagttgac ctctacatct taaccatata tattctccac
    28021 tacgattttt agccctaaat tccactgtat gataatccat ctggttttta cctatttcag
    28081 tgtttgactt ataaaaacga ttccagtctt ctggatgtac aatttttttc cagtaaataa
    28141 gcggattttc aacaatttct cctggtaagt caaataattc aacttgtgat ggtgaatatc
    28201 gaaatacgcc tgttttcata ttgcaaatgt atatatattc atctgtacct ctaatcaaag
    28261 catcgtaaag caatgtagaa ttataatcaa aattgtctct tgaaaaatta aaaactcctt
    28321 tttcttcttt attatttgat atttcatgaa attcattaat cttaattggt ttatttaagc
    28381 ttgttgagtt tgcaatatct attgattgat gcatatgaac aactgtgcca tcttgccatg
    28441 taattaaact atcataattt tcaaaaacac gatttaactt attacatttt tcataccact
    28501 ttattaatac tcctttttta tcattcttta ataattctaa aactttacaa aaactacaag
    28561 tagaattttt ttcaggatat aatacttgcc aacaaacttt tccttctgga tctaaaatat
    28621 tatattcttc tttcattttt ttgttcataa aaataatttc attagtatga atatttgtaa
    28681 catatatatt aatctgtagt tgatttaata taacttcaaa attatgtttg ttcatatact
    28741 tatctcctcc atagttactg ctctttataa caacattgtt aaaattattc tttttagaag
    28801 atttacttat aacttataca tatacactaa ataccttaat ttaattagaa agtttattac
    28861 ttcatatttt aaattataat tgataaaaaa aaatacagca atatagtatt accaatttaa
    28921 aaaaaattaa tattacataa tacatctctc tcttatatta aattttaact tggtactaat
    28981 cttgacaaat tgtccacaaa aataaattat agattttatt attgttttaa atttttataa
    29041 aaaatcagta ttattgatac tattgaaatt aaaaagcatt aatttctaaa aacatcataa
    29101 tttttctaat agacttaatc acttttaata tatatagtaa aacaaaaaac ttatatttta
    29161 taaatatcat aattttttta ctgatatttt attatataaa ttttatagaa ttaattgtca
    29221 attttttatg aaaatggtaa gatatttatg gatggtatct tgttataaga actatacttt
    29281 aaatgttttt aattattttg tcttatgtaa ctcatatcct caggaatgag attaaaaatt
    29341 aagatgttgt atcacaaagt ggaggtgata ctattaaaat aggctttatt ggttctggaa
    29401 aagttggaac atctttggca aattattttt tatcaaaagg ttattgtgtt tcaggctttt
    29461 atggaaggaa tcaattatct ttattagaat caacaaattt aacaaaaaca aagatttaca
    29521 gcaatttgaa agatataatt tatgaaaacg atatattatt tattacaaca tcagatgatt
    29581 ctattgaaat tatagacaaa aaactttcca aatttaattt aaaacataaa tacatttgcc
    29641 acacaagtgg ctctttaaaa tctagtatat tgttctgttc aaaaaaagca ggtgcattaa
    29701 tttattctat ccatcctata tttgcatttt ccaataaaaa taccaacata aaaaaaatga
    29761 aagacatttg tttttccata gaaggtgata atgaacaaga tgatttagtt attcaaaatt
    29821 tcatagatga tttgggaaac caatttttta taagagataa ggatacttca tccacttatc
    29881 atttagctaa tgttttagtt tcaaatttag tattatcttt actagatata ggagtaagtt
    29941 actttattaa attaggttta tctgaagagg aatctttaaa agctatcagt cctttagtaa
    30001 aaaaaaatat agaaaatata cttgataatg gctttactaa agctcttact ggtcctgttt
    30061 ctcgtggaga tataacacca ataagaaaac atctatctgt attggataaa aaagatgagg
    30121 atatttacaa aatactatcc ttaaacctac taaaaataat tgccttagga aatgacaatt
    30181 cattaaaagg tataaaaaat attactatag aaaatgcaat cgaaaattta ataagtaaat
    30241 ctgaaaaata caaagaaatt tacaaacttt taggaggaaa aaacgatgaa aaataccata
    30301 cagactttta agaatgctaa atatgaagga aaaaaactat ctatgcttac tgcttatgac
    30361 tactcaattg caaaaataat ggatgagtgt gatataaatg gtattttaat aggagattca
    30421 ttaggaatgg tcataaaagg tgaagaaaac actctatctg ttaccataga cgaaattata
    30481 tatcatacaa aagctgtaaa aaatggtgta aaaaatgcct taatcgtaag tgatatgcct
    30541 tttctatctt accatgtttc tatagaagat gcagttaaaa acgctggtag acttataaaa
    30601 gaaggaggag ctcatgctgt aaagttagaa ggtggctcaa acgttataaa gcaaatagaa
    30661 agcattgtaa atgctcaaat acctgtaatg gggcatttag gattaactcc tcaatcagta
    30721 aattcatttg gtgggtttaa ggttcaagga aataccagtg aaacagcaag acaacttatt
    30781 gaagatgcta aattaataga aaaagcaggt gcattctcta ttgtccttga aggagtgcct
    30841 acgaaaatag ctgagatggt aactaattct atttcaattc ctacaatagg tataggggca
    30901 ggaattaact gtgatggaca aattttagtt tatcaagata tgttgggaat gtttggagat
    30961 tttgttccta agtttgtaaa gcagtatgca aatataggag atataatgaa agattcaatt
    31021 aaaaattaca tcctagaagt taatacaggt gcatttccac aagaaaaaca cagcttttca
    31081 ataaatgaat ctgagttaga aaaattatac taatattaag gatggtacaa aatgcttgta
    31141 aaagaaatta aattactaag aaatataatc aaagattgga gaaaacatgg ctattctata
    31201 ggccttgtta caacaatggg atttttacat gaaggacacc aaagtcttat aaaaaaagct
    31261 gtaaaagaaa atgataaagt agtagtgagt gtatttgtaa atccaactca atttggacca
    31321 aatgaagatt ttaatagcta tccaagagat atagataaag attttaaata ttgtatggat
    31381 agtggagcaa cagtagtctt taacccatca ccagaagaaa tgtatttaaa aggtaattgt
    31441 actaccatta atgtttctgg acttacagat tttctttgtg gagctaaaag acctgttcat
    31501 tttggaggtg tctgcctagt tgtttcaaag tttctaaata tagtaacacc tgataaagct
    31561 tattttggag agaaggatgc ccaacaatta gctgtaatta aaagaatggt caaggattta
    31621 aacatagata cagaaataat aggctgtcct ataattcgtg aaaatgatgg attagcaaaa
    31681 agttcgagaa atacatatct ctctgaggaa gaacgaaaat ctgctctaat attaaataag
    31741 agcttaagtt tagcaaaaga agaattagta aaaggcaatc taaatccaga gaatataaaa
    31801 gaattaataa cagctaaaat aaattctgaa cacttagcaa aaatagacta tgttgaaatt
    31861 gtagatagtg agacattaca acctgttaag caaatagaac attctatact tgtggcaatt
    31921 gctgtgttta taggaaaaac cagactaatt gataatttta catttgagtt aaatatatag
    31981 tctataattt tatataatat atctaaaaaa taatagaata cctaaaaagt aataaattac
    32041 ctaaaaagta ataaattacc taaaaaataa taaattgctt agaaaataat agattacaat
    32101 aactaaaatt ttaaaattaa attccttaaa agtatgatta attataatta tataagtata
    32161 ttcttattac acttatatta atttatatta aatatctact aactcaaata ttcataatta
    32221 aactttaaac tggataaatt ttcttttaag aatgaaagtt tatccagttt tgcgattata
    32281 ataaccagtt ttacatatcc acttgtaaaa tatatctaag caatatatca tactatatag
    32341 atttatgagt gaaataatat ctgctattta ctgaatattt ttatttttcg ttttttaggg
    32401 ggattagttg tgtttaaaga taagattgat gaatgtgttc atataatgac tgcatatatt
    32461 gctagtttaa aagaatacta ttcattcata gaaactcaaa ttggtgattt tattaaaaaa
    32521 tatggagaag atgttgtaga gttatgtctc catagagtga tgattctact atgcgaatgt
    32581 ggtttggcat aaaattaaat ttattaaaat gggtaagaag aatcctatat aatattcttc
    32641 ttacccattt taatatatca atttcatagc ttatcgttta aaatatttta catccattac
    32701 tagacaactt tacattctct ttttaattct agtatattta aatcatttta gttgctcctt
    32761 atttattctt attacttgtt ttattttata aataaaataa ttctttttaa taatgttttt
    32821 tgttgatatt cctatcacac atccaattat ttatcattgt cttgaaattg tttgcatact
    32881 taatttaatc caattgaaac actccagcat agaatcccct gtaaaataga agttggatta
    32941 aatcctaaca tctatacaga aaatactact ccaagcacaa gcaatataat ggaatatatt
    33001 tatcacttaa ttttttatac tttttaaatc ccatacctaa aacattaagt gcagctatta
    33061 gaattaataa ttgttgtggt ataaaattat gcttgcttca tatttattca ttttttgcta
    33121 taaaagttct tgttttacaa aaaacatttg ttttgtatca aaataatact tataaattac
    33181 ataattctca taaaaatttc tagtattact tgtactctta ataaataata gccaacaagt
    33241 accttaaatc attatatcta tatctaataa gaaacacagt aagataattt tttcgcccat
    33301 aacttaataa aaactgttga tattagtagc aattgaattt agttaattta tttataatat
    33361 acataaattt aaatattacg aataaagtat tataaatagg atactttcta aagggaggaa
    33421 attatgatag ataatcaaaa atatgttatt ttatcactag aattacattt atttttttca
    33481 agaattatga aagagcatgc tcttttttta gaagcaggat tcacaaataa aaattataat
    33541 cttgctatgg aagctgacca ctataaaaag caatttgaag atttattatc atacactgtt
    33601 agtgctagta atggtataat tagacctgat atattatatt cagaagaact tgtaactact
    33661 ctcacatcag ttgcagaaca aaaaacagaa gagtttacag ggatagaaat aaacaaaaac
    33721 atcactacaa gagaattaaa tctacaaagt ggtgtagacc cacaagttgg tcaagactta
    33781 gtgaactatg tagctcaact taactctgat gcaataagat tacttgatgg gcttattaat
    33841 tttaaagaaa gagtcttaga tggtgtacta tcatgtacta tatttacatc aaactaccct
    33901 ctacttcttg aacatataat acatgaagca aatttatatc gttcttatgt agttgacctt
    33961 gaaaataaaa tagatattga gtcaaaaaac gctaaagaaa tagaattatt ctgggaccat
    34021 attatgatgg aacatgctct gtttatgaga ggattactag acccctcaga aggtgaacta
    34081 ataaatactt caaatgattt tgctataaaa tttaatgaat taattgaaaa aacaaacgaa
    34141 atgactgatt ctaatatcaa gaacattaca gaagaaactc taaatgaaac tgttgagttt
    34201 aaagatttta aagaagcagg agcatcagga atagaacagt gtaagataaa atctataata
    34261 ttaccacttt tagcagacca tgttttaaga gaggcaaatc attatattag aatattggag
    34321 agttataaaa acatgtaatt aaaaattact tttaaaataa tctttgcata tttagataaa
    34381 ataaaggtac agttaactgt acctttattt tttataaact tataaaattt aaacaagtta
    34441 ttcataaaat aaaataataa tcatctataa cccacaactt tattttatat taaataaaaa
    34501 gtattagtga ttatgtttta taagtatttc tttattcagt tatttattaa aaactaatag
    34561 taaatcttat actaatcgca tatttatgtt ataactatat tgtaactatt ttcgtaatct
    34621 taggaaaaga ttacttataa aattaacctt atacaataat atatcgtata atcttaatta
    34681 gcataatagt tacaatatta aaatttaaat atgggagtga ttttagtatg ataagacaaa
    34741 caccattaga gaaacgatat gacaagctag gtcctcatat tgtaacagca ctcaaaaaac
    34801 gttattttga tgcttattac tgtaaaacta gaaataaagc tttgcaacaa attttagatt
    34861 taattcctca aaatcatgta gtatcatggg gaggatctga aacacttaag gaaatgggcg
    34921 tacaaactgc tgttagagag aaaggattta aagttattga tagagattta gcaaaaactc
    34981 cagaagaaag aactgaaatt atgcgtcaag cacttctatg tgatactttt ttgatgagta
    35041 gcaatgcaat tagtgaagat ggacaactct ttaatattga tggaaatggc aatcgtgtag
    35101 ctgcaatgat atttggtcca aaaaatgtta tagttgtagc tggtatgaat aaaattgtaa
    35161 aaaacattga tgatgcaata caaagaacta gaacaattgc atctccagca gttgttcagc
    35221 gttttcaaga tgtcaataca ccatgctata ttaatggaag ttgtatagat tgcacaagcc
    35281 ctgaaagcat ttgtgcatac atggttacta caagaatcag tcgtccagca aaaaaaataa
    35341 aggtaatatt ggtaggagaa aatcttggtc tataaaatat acatacatgt aaatagctct
    35401 ataaataata aaatcatatg aaataactta tttctaaaag tggtagaata aaagcttcta
    35461 caagactttc attctaccac ttttatattc ttttaatttg tgtttctata ttattaattg
    35521 ctccgatttt catatatatt actaactatt tttattttca taattttttt gttcttcatc
    35581 aagctgttta taataatctt tattatagtc agctagataa tctataccac ctcctgtaat
    35641 cacatttaat aatttcattg cagattcttg attaacttta caaacataat tatcaccaga
    35701 tttaacaagc tctaatgtaa tattaaattc ttttttcttt gcagaatcaa tatctttcat
    35761 agttggattt ggcatcattt ctcctagttt aggaggattc ttttttaaaa tagaaaccat
    35821 atcagtattg ttaattttta aatctacagt cactttatcc ttattattct ttatatctga
    35881 aatttcccaa gtcatatttt tagaatacat tttaaatcct tctttatctt cgtatataag
    35941 attacctaac cctgattttg ggaaatactt atcaacagta tctgcatctt gtgtttttat
    36001 tgaattaaac atactatcca cttcattttt tatcttatta tcattagtac aaccagctaa
    36061 caccagtact gatattgcaa acattataat acatataata aatttcttca ttaaattata
    36121 tccccctata cttttttgca caaatattat tctctttttt atcttttgaa aaagttgtag
    36181 taattgcatt ttgtggacaa acttttatac attcaccaca cctaatacag tctggactat
    36241 ttacatcttt atatattggt atatcaagct tacattttgt ttgacatgct gtacaatttg
    36301 tacatttatc tttatcaatt ttaaatctat atattgaaat aggattaaaa aaaccataga
    36361 ttgctcctaa agggcatata tacttgcaaa atggcctata agtaatgatt gacatcaata
    36421 atatcaatag caaaatactt aacttccagc taaataaaaa tcctattgat tctcttaaat
    36481 tctcatttcc taaaataagt ggtattcctc ccaaaagtgt tcctgaaggg caaatccatt
    36541 tacaaaacca aggatttcca ccccctgcta catttacaat agcaactggc aaaataatta
    36601 caaacattat taagactata tactttagat attttagata tttatcacca taaacttttt
    36661 ttatctttac tggaaagggt actttatgta gtaaatcttg tacaagtcca aagggacaaa
    36721 gccaaccaca aacaaatctg ccaaaaaaag caccaaatgc cattaaaaaa ccaacaacat
    36781 aaaatgagaa tttgtactct ctgcttgata aaactgcttg taatgaacct attggacatg
    36841 ctccaagtgc acctggacat gaataacaat tcaatccagg tacacataat tttttacttt
    36901 ctcctccata tatagttcct tctaaaaatc catttacata tccatttgtt aatgctgtaa
    36961 atgcaacttg agtaataagt cttatattat tatttacctt agataataac ttcatccctc
    37021 ttctcctaac caataccaat acactcaaga caaatcataa ttgctttagt taatactgta
    37081 tttgtttctc cacgatatgt acctaatgca ataaatataa tactaattgc aataatagaa
    37141 atgccttttt tattatcttt aataaagtta ctcattggct tttaccattt ttagtctttc
    37201 atctataatt tttttccaat cttccttact atttgcacct acaaccttct cacccacaaa
    37261 gtttcctttc ttgtctacaa aataagttgt tggaaactcc ataactcttt taaaatcagt
    37321 ttttttaagt tcttcagata cagtcaattg ttggtaagtt gcatctgact ttttcataat
    37381 gtctttaact aaatttttct cttcatttga aagaccagtt ctcatatcag ttttatcaac
    37441 ttctacaact aatcccttta tagctacatt ggaattatta ctctcatatt cttttgataa
    37501 tgcttcaagc tctggcattt cacccacaca tggtccacac caagtagtcc agacattaat
    37561 aagagtaagt tctttatttg aaaatatctc ttttgttacc ttatttccat caacatcctc
    37621 cgtatctaaa ttactaaacc attcactatt attcttgttt ttttctactg gcttagattc
    37681 ttttttgcta catccagaaa tcacacctaa aacaaaaata catcctaaaa ctactatgaa
    37741 aaaccttttc atatctcaca ctcctagaat ttatatagta tataaaatcg ctgcttgaaa
    37801 taaaaataac ttatcttcta tattaaagta attatattta ataaataaga gctaatttaa
    37861 aaaaagatat acagttaaaa tctatttctt ttcagacaaa atcttatata tatataatag
    37921 cttgtaaatc ttaagattat atacatatat ttctaaagat tttcttaaga aacagttaga
    37981 ttttactaat ataagtttat taattagcat tatactaatt tatcttaata tgattttttg
    38041 ttgattttaa gctgtttatc gtataaataa aatttttctt gactatatag ttactatata
    38101 gcttattata tatagagagt aataaaagga ggtaaaattt atggaaaatt tatttacaag
    38161 aaaattcact acttttgaat ttctaaaatt tgtttctcct gcaattatat ccatgatatt
    38221 tatatctttg tacacaataa tagatggcat ctttgtatcg acattagttg gttctgatgc
    38281 tcttgctagt ataaatattg tactacctat aattaacctt gtttgtggat ttggaataat
    38341 gatggcaact ggtggaggtg ctatcgtttc tatacgtatg ggtgaaaata gacaggatga
    38401 agccaactct acattttctt ttatagtttt gttttcattg attgttggga ttttattcac
    38461 agtaatctca tatttcttta tcaaagaaat atctattttg cttggtgcaa cagataagtt
    38521 attaccatat tgtataactt atggtaaagt tatgatttta tgtacaccat tttatatttt
    38581 aaaatttata tttgagtact ttgcaagaac tgatggaaat tctaaattta gtttatttct
    38641 atcagtcatt ggtggtgtaa caaatataat attggattat gtatttatta aatattttgg
    38701 aatgggtctt ttaggagctg cagttgcaac tgctataggt attattttaa cttgtgtttt
    38761 aggtattatt tacttcttat ctaataaatc tacactaaaa ttaagaaaac caaaaaccga
    38821 ttttagactt ataagagata ctatgataaa cggttcttct gaaatggtta cagaattatc
    38881 tacaggaatt acaacattct tatttaatgt agtagcttta aaattagcag gagaaaatgg
    38941 acttgctgct cttactatag tattgtatgc tcatttttta atgacatcag tctatctagg
    39001 attcgctgct ggagtgtctc cattaataag ctataatttt ggtgctgaaa acagtgataa
    39061 attaaaagaa acatttaaac attctctaaa atttatattt gtttcttctc ttttagtgtt
    39121 tattattgct ttagtatttg caccatttat tgttagggtc tttgtaagtc cagataacac
    39181 agtatttaaa ctagccttac aaggattaaa aatatttgca tttgcttttt tgtttgttgg
    39241 tataaatata tttgcatcag gattttttac agcatttcac aatggaaaaa tttcagctat
    39301 tatatctttt agtcgtgcct ttgtttttat aatcatagga atcataattc ttcctcctat
    39361 gttaaacatg actggattat ggcttacagt tccatttgct gaggttataa ccatatttat
    39421 atctattcta tttataaaaa aatataaagg tagatataag tattaaaaat taatacttaa
    39481 aatcaacatt tattaaaact aataaacctg ctttaaaata caaatttaca aatttgattt
    39541 ttaagcaggt tttattttag ttataataag tcatttgcat actctttaat tggtgctttt
    39601 ctaagtaata aaattataaa tattatgcaa ataactataa ttcctacctt tgttccaaat
    39661 aaaataaaag gattctgaaa tgaataaata attttttcta aatacaatag cattttatgc
    39721 atatttttag ttgcaaaatt aactatataa attaccatta atatcggtaa tcctatcaat
    39781 atagtaatac tagtaacttt tctaactcta tatgtaaaag ctccaagtaa cactcctata
    39841 aaacctatac atatttcatt tatacatatt tgtacaaaat aatttaaata agttagtggc
    39901 atacttgatg ttgaaggatc tatcagtgct gatatagatg tccaaatcat atctctcttt
    39961 agtaaaactg atagttctat actgtaacct gttataattt ctataaataa cttcgataaa
    40021 aaaatcaaaa ctatacctaa aatagaaatc acaaagctta aaataattaa atctatgaca
    40081 atagctttta tacaactttt tctatctgct cttatactta aagctcctga aaagtcttta
    40141 tttgctatat ttactccata cacaaatagc agtatagtta tatatgttaa aataggattc
    40201 acaatcgtgg ataaattagt tttagatgct tctccaaaaa tcttgagaat aaacactggc
    40261 aaaatattca taacaattcc cacaatcata aatataatta tatacaattt agtattttta
    40321 ttaaaaaatt ttatatatgg ctttaattca ttcaattaca attcctcctt cttagtcatg
    40381 ttaacaaaca tatcttgtag ccctatgtat cctacatcaa tatttgaatt tttaagtatt
    40441 ttttcatcat tttcactaaa atcaccatag taaaaataag caactgcatt tccaaatgcc
    40501 tttttaggtt ttatattttt tatacattct aatttttcta actcttcttt atttccagta
    40561 atataatgag ctttttgttt tatgacatca atttcttcat ctataataat ttttccctca
    40621 tttaatatta ttacatgctc cagtaaatca tctatttcat caatcaaatg agttgatatt
    40681 attattgtcc ttggattttt tatataacta tctaaaatta tgttataaaa ctcttgtcta
    40741 tttactgcat ccaaaccaat tgttggctca tcaaatatgg tgatagctga attagaacaa
    40801 atacctatta tatttgaaag tatagttttc atacctcttg acagttgttt atactttttt
    40861 ttagtattta aatcaaaata tttgcataat tctttttcta agcctttatc ataactttta
    40921 taaaaactag aagaaaattc aaatatctga cctactttaa aatctgaact ataaaattct
    40981 ttttccctga caatacaaac ttcttccaaa acttttatat cttcttttgg gttctttcct
    41041 aatatttcta tctcaccttc attttgaatt aactgattta ccattatatt taataatgtt
    41101 gtttttccag ctccattctt acctaataaa ccatatatct tatttttttc aaagtttaga
    41161 gacatattat taaaaatatt ttgcttctta aaactgtgag ataaattttc tatcttaata
    41221 gaactactca tatattaatc ctccttgaaa ttaattataa tatcaaccaa ttcttctcta
    41281 tttatttcta atttgttagc ttcttgaagt aggtttttta caaaattatg tttaaaattt
    41341 tcttttctag cttcttttat aatagttttt gcaccatctg atacaaacat ccctatcccc
    41401 ctcttcttat ataaaatatt tttatcaacc aatatattta taccttttaa tactgtagct
    41461 ggattaattt tataaagctt tgaaagctct gttgttgatg gaacctgttc ttcttctttt
    41521 attccatttg atagtatctc atcttcaatt gctcgtgcta tctgaataaa tataggttct
    41581 tcattattta atactaattt cataggttcc tcctttctcc attagttagt tactcaacta
    41641 attaactata taacttataa tatcttgaaa aatattttct gtcaatacta aataaaaaac
    41701 agagggaaaa ttccctctgt tttttgttct ttatatttat aattaaattt taatttttgt
    41761 aatcctatcc cataagttaa aaactttaat aatctgttgt atcttcattt tttaatattt
    41821 tacatattga gctagttcct aacctttctg ctcctgcctc tataaatttt tctgcatcag
    41881 aaattgattt aactccccct gcagctttta tttttacatt ttttccaaca tgctctttca
    41941 taagctttat atcttctaaa gtagctccac ctgttcccat tccagtagat gtttttataa
    42001 aatctgaacc tgacattgtt actatttcac acatttttat tttttcatct tcatctaaat
    42061 aacatgtctc tataatgact tttaatactt tatctcctat agcttttttt atttctttta
    42121 tttcttttcc tatattatca taatctttat tttttatatc tgaaatattt acaaccatat
    42181 caacttcatc tgctccattt tcaatagcat cttttgcttc aaatactttt gtagcagtag
    42241 tttgatatcc caaagggaac cctatcactg tacatatctt tattttacct tttagatatt
    42301 ctgatgctct tttcacatat gatggtggta tgcaaactga tgctacactc atatctacag
    42361 cttcatcaca taaaatttta atatcttccc atgtagttgt agcttttaaa atagtatggt
    42421 ctactgtttt taatatatgt ttcataaaat cctcctaaat ttataattaa tataattaga
    42481 ttactttttt aaatgcaatt ttctctttgc aatgtttagt atcatatcaa cctcttcaac
    42541 tttaaaaata atcattagta gtgtataaat tccacctcca actataactg aaatagctag
    42601 tgatacaaac tcattaaatg ttcctactcc caaaattcca aatataaatt tatacgtaaa
    42661 gtatgataaa acacccataa ttaaagatgc aactaccgat ttcaaagttg cttttattat
    42721 tttatcttgt ccaaaatatc caacttttct ctttaggttc aagaagagta acaatataca
    42781 tgcaattgat gatgaactag ttgcaagagc aagaccacca tgagccattg gttttattaa
    42841 aactaagtct aacactatat ttacccctac agatataatc ccatttacca taggtgtttt
    42901 tgtgtcttgt aatgaataaa aaacctttcc caaaatatct cttaatccaa atgcagtcat
    42961 accaactgca taaaaaatta aggcagttgc tgtcatttgg gttgccctcg catcaaaagc
    43021 acctctctca aaaatgattc taacaacagg agttgcaaaa aaaatagaag caactgaaat
    43081 aggaatcata gaaattatta tcatatttat actagattta actgaactag taaacttctt
    43141 ttgattattt tctgcactta acttagataa cataggatac ataacagata ctattgaagc
    43201 tgtaaatgtc cctgtaacaa aaccatttaa tctatctgca taagtaagtg ctggaatgct
    43261 tcctttaact aatgttgagg ctaaagttgt atctaccaat gagttcactt gattaacagc
    43321 aacacctata aatactggtg aaagtaatgc tagtaattta ataaggctat catctttaaa
    43381 gtttaagtag tataagtatt tgtagttcgt ttttttaaca aaaaacatgt aaaagagcag
    43441 ttgaactacc atagcaacca cagcaccaat tggaagtatg tatggtccaa atatggtact
    43501 taacattatt gaaataatta ttactatatt atagggtata cttccaaatc caactacaat
    43561 aaagttctct ttaatttgta aaaatgctga cataacactt gtaataccta tgaatattat
    43621 tcctgttctg aacctcccat gactaaagtc acagggttcc tgcttcatag aattttgcat
    43681 actaaaatat gtcttactaa ttctccacag gctatccccg tagttcctac ggttcttaca
    43741 taagttattt attttgaatc gttattagtc ttaatccttc ttttaatata tttatacttg
    43801 catttatatc tctatcgtga gtttcattac aactaggaca aatccattct cttatattta
    43861 agttcttaac ttcctcgttt ttatacccac atttattaca tatttgtgaa cttgcaaaga
    43921 atttatctac ctttacaatt tgtctaccat gccaattagc cttgtattct aattgacgaa
    43981 taaactctga ccatgataca tcagaaatta agcgagatag tttacgattt ctaataatat
    44041 tctttacttg taaatcttct atgcaaataa tatcattctc ttttattaat ttagtagtta
    44101 atttttg
//
LOCUS       DAFAZV010000031        44025 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFAZV010000031 DAFAZV010000000
VERSION     DAFAZV010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 44025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44025
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.031"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..378)
                     /locus_tag="KOU88_002439"
     CDS             complement(<1..378)
                     /locus_tag="KOU88_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212311.1"
                     /translation="MIAVKKAYKFRMYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNDKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKTGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQ"
     gene            complement(1027..1434)
                     /locus_tag="KOU88_002440"
     CDS             complement(1027..1434)
                     /locus_tag="KOU88_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212312.1"
                     /translation="MSKVAKATFYLMIVTIISKILGMGRELVLSSIYGTGLYTESYLT
                     AMNIPNIIFAAIGTAIVTTFIPMYQDISSKQGEKQALKFLNNVLNIIVGICIVVAILG
                     VIFSKQLVSIFAIGFEGERFLLTVKFTKILIKK"
     gene            complement(1908..2792)
                     /locus_tag="KOU88_002441"
     CDS             complement(1908..2792)
                     /locus_tag="KOU88_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3212313.1"
                     /translation="MDTKKENNYENYICVGSSNVSNAMKMYLKEIEEYKMLSAGEEVE
                     LAKEIINSSSVAKEKFINSNYRLVVSIAKRYKRDSIDMLDLIQAGNIGLIKAVEKYDY
                     KKGYKFSTYATWWIKQSITRYIDDCENTIRIPIHLHQRINFVKKKKQELLNVLLREPT
                     IDEIADACGLEVDKVLELLRRDKNVVSLDTPLKEDEDSSLVEFIPSDADFKDVVIHEV
                     EQHNLKEKIEELLTGLGEQEQQVLRMRFGIDDDDPKTLEQIGKVFGVTRERIRQIEAK
                     AIRKLRHPSKLKQLKHFY"
     gene            complement(3083..3559)
                     /locus_tag="KOU88_002442"
     CDS             complement(3083..3559)
                     /locus_tag="KOU88_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBK3212314.1"
                     /translation="MSKELVKDRVIKYLIEDLLVPQDMIDTNVELAEFEEGAEGILDI
                     VVNVKDEEDYYAPVMIVQCLDEDVELEGEVLQKQIEFLEEVDNITMSGRLVLTNGDAM
                     MYADWRGEEYDTEAALPTYDIMVKEFHEMEQQAKDLEEHHHHDENCGCGCNHHHEN"
     gene            3826..5001
                     /locus_tag="KOU88_002443"
     CDS             3826..5001
                     /locus_tag="KOU88_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HBK3212315.1"
                     /translation="MKFKKQISSIVVSTMLVLGSMNLSYADGTNVVTLGANLSESQKQ
                     QMLNYFGVKKDQVLVLDVTNAEERQYLQGVATEGQLGKVTISCSYVEPTKKGNGINVK
                     TANLTWVTSSMIASTLTTAGLEDANVIAAAPYPVSGTGALTGIMKAFEDASGKKLDET
                     KKEIASEELVVTGDLGDDIGQEKATGVMNDIKTEIVKNGTKDTNQIANTINNVVNNYN
                     ITITPEQKEQIKGVMKKIADQNYDYNSMKNTLDNVSDNVNEQLKKLGESVKGSGILDT
                     IGGWFSGIGDWFSGLFSGGDKKDLGILNNTNDESLGSDAVINSTEGVQINPQNNTNSN
                     NDSDTNSSKNDTSSNNENNDSSQTNENNTTNNSENQSNNNDSVGFFEKIKNWLSGLF"
     gene            complement(5082..5885)
                     /gene="proC"
                     /locus_tag="KOU88_002444"
     CDS             complement(5082..5885)
                     /gene="proC"
                     /locus_tag="KOU88_002444"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBK3212316.1"
                     /translation="MKKIGFIGAGNMASAMIGGIVNSKLVEPNMVIASAYSQGTLDRI
                     DANFGINTTKDSKEVTRTSDIVIVAVKPDIYDDILEEIKDFIDDNKIIVTIAAGKSIK
                     DIESIIGEDKKIVRTMPNTPALVNEAMSSLSINKNINKEDLEAVTEVFNSFGNTEVVP
                     EYLIEAVIGASGSAPAYVFLFIEAIADAAVIAGMPRPQAYKFASQAVMGSAKMVLETG
                     KHPGELKDMVCSPGGTTIEAVKVLEEEGFRASVIKAICACIEKSKKMSE"
     gene            complement(5925..6509)
                     /locus_tag="KOU88_002445"
     CDS             complement(5925..6509)
                     /locus_tag="KOU88_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212317.1"
                     /translation="MNKDIGAKIKQLRTQKQMTLKDMSEKTNLSIGFLSQLERGLTSV
                     ATDSLGKIASVLDVELTYFFMKPKEHKRAVLRSYEKEVFDVENSTFIHYHLSSSLKEK
                     TMLPRLIEILPSKSSEEICCYVHEGEEFVYVLEGTLTVFLGDEQIEMYPGDTIHYNSE
                     KNNHNWVNYTNKVVKILVVSIPNPFEKSDAVKEA"
     gene            complement(7394..8002)
                     /locus_tag="KOU88_002446"
     CDS             complement(7394..8002)
                     /locus_tag="KOU88_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBK3212318.1"
                     /translation="MEKDFFRKNGIDLAKSILGKYLIRKYENKVIVTKIIETEAYMGV
                     NDKGAHVYGNKKTDRTKPLYLDGGHIYVYLIYGMYNCLNLSANIENVPECVLIRGVEP
                     ITSLDEISMNRYNKAYTELSKYQVKNITNGPGKLCKALKIDRSLNSKSIMGEELYISD
                     FYYDDKGKKVFSKDELDIKTSKRINIDYAEEAKDFLWRFYIE"
     gene            complement(8111..10849)
                     /locus_tag="KOU88_002447"
     CDS             complement(8111..10849)
                     /locus_tag="KOU88_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain-containing sensor histidine kinase"
                     /protein_id="HBK3212319.1"
                     /translation="MESKGTLSKNKVYILANGLFLVIALLNINLYTVSINMYRIILLW
                     IFGYSIVYISSFKTDEFINILKVGCLVLVFVSILGVVNLKIQKFQIVLLNLSIINMST
                     FIYLTISKVKKLRISPILIFYSAFVILDYFIRNIFSDINWNMIIILINICISMFNLLY
                     LLNKLDSNIEHYKLIKDLTYFVFFTTIICFVAISKINIVDSDRLIGVIYLLLCNHTYY
                     VYVYSLNNRVVYPYYELDSINKKLSKKSEQLGKINLAIEKDMIIQRTLKNYIDQRKEL
                     LRQALDTIPNVWIVTDYDFNISYTNNKFKDEFSKDMNNYYKILTFIKEDEKVAEKLKK
                     FDNDISIIDKLVELNDKIYLLSLSNNKDESNYLISLNDITNEIKIDEEIRNINKDYEN
                     IILNIPSPILVRSAEGGIKKNKVISINKKYEKSFKCVSSDLVDMTLEQYFETFNIDFF
                     DNREFKRLNLTQEKKAEIVSYNDTANCIVNFVMSDSEGEEHVEEVRVGDYWSDNKLFK
                     LLTFRDITKEINILRTVNEQKIIYEKLLDVIPEAIFLEDLSTSRVLYTNRTFRELFGI
                     SSDVLGVTTQKYRNILVKKYINNLNIGEREKSIHIVNENNHIKEVKMISRTLYFGQKR
                     SRVRIIKDLSVQRESERLKKALIKQRQYDQMKMEFYANISHELKTPLNNIYSSVQLIE
                     NLYKKGKIIDFQDILKEHIKITKQNMFRLLRLIDNIINISQVKSDIYKIKAVNFDIID
                     ITERIVTSISSYAKSKGIDLIFDTDEETVMVGLDPESIERIILNILSNAIKFTLEGGE
                     ILVGIYKKDETVEIIIKDTGVGIDKEKLNDIFNRFKQIENSGISNEFGSGIGLCLTKS
                     LIEIQNGKIYIDSKVGEGTNVKVIFPIKEVVEEVYDNSNYNDNIEKFEIEFFDIYK"
     gene            complement(10997..11788)
                     /locus_tag="KOU88_002448"
     CDS             complement(10997..11788)
                     /locus_tag="KOU88_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011987989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK3212320.1"
                     /translation="MKLKKLLSVALVSAIAISAVGCSNKEDKKILVGASSNPHAKILE
                     VAKPLLKEKGYDLEVKIFDDYVLPNTALDEGSLDANFFQHIPFLEETVKEKGYKLTYT
                     SKVHIEPMGFYSEKVKSLDELKDGAVIAVPNDATNGARALKLLAKNKLIEVKDGELIT
                     KKDITKNPKNIVIKEMNAEQLPTVLKDVDGAVINSNYALTANLNPTKDAIVIESSDSP
                     YVNIIACRENNKDSDKIKALSEAMNSKEVKKFIQDEYKGSIVPAF"
     gene            complement(11824..12480)
                     /locus_tag="KOU88_002449"
     CDS             complement(11824..12480)
                     /locus_tag="KOU88_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212321.1"
                     /translation="MNSLIDFLTTLFPNALLQTLYMVIVPTIVATILGFILAIILVVT
                     KPDGLKPNSTINSALGFIVNIFRSFPFMILIVAMIPITRLIVGTSIGETAAIVPITIG
                     AAPFIARIIESSLNEVDKGLIEAAKSFGATKRQIVFKVMIKEAMPSIVSGITLSIISI
                     LGYTAMAGAVGAGGLGNIALIYGYQRFDTAVMVYTVIALIILVQIIQGVGNLAYKKLK
                     "
     gene            complement(12473..13438)
                     /locus_tag="KOU88_002450"
     CDS             complement(12473..13438)
                     /locus_tag="KOU88_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HBK3212322.1"
                     /translation="MISIKNVNKYYGKIQVLKDVSIEIESGEIFGIIGHSGAGKSTLL
                     RCINGLEEYQEGSVLVSDKEVKSLNEKQMRDLRKELGMIFQHFSLLERKTVFDNVALP
                     LECFGYSKAEIKKRVLELLEVVGISEKKNDKPRNLSGGQKQRVAIARALALNPQVLLC
                     DEATSALDPNTTKSILSLLEDINKKLGITIIVVTHQMEVIKQICGRVAIMENGEVLEV
                     GDTEEIFLRNTKGLRKLIGEESIILPKGTNIKILFPKDISNEAIITTMARELNIDVSI
                     IFGKLEQFKDDILGSLIINISDKSGEQVKQYLTSKGIRWEEMINE"
     regulatory      complement(13544..13650)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(13940..14884)
                     /locus_tag="KOU88_002451"
     CDS             complement(13940..14884)
                     /locus_tag="KOU88_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HBK3212323.1"
                     /translation="MSRAERLIELMITINAKRSFTAGELAEEFSVSKRTILRDLQVLE
                     SIGFPLYSKVGAAGGYHVLKERILPPIAFSESEVKSIFFAYQSLEYYNDLPFEQETIS
                     VLKKFLNCIPNDIQYNIENIRRKFVFWTPDRHCSTPLLKELFNVVMNESTIKIEYSSK
                     QKNSVRTIVPIGLYAMNGLWYCPAYCIKSESIKEFRVDRIVKILSIENLSSKKYKVLS
                     SIHDYLKNMEVGTDYHIKINLTDEGVKCCETEFLLARGLKILSKGGYIDMYIPKSTLN
                     WVAEYFLTFGKNATIIEPIELKHLIKSKVLELYNHHCI"
     gene            14995..15462
                     /locus_tag="KOU88_002452"
     CDS             14995..15462
                     /locus_tag="KOU88_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212324.1"
                     /translation="MENNTIKADDIINYCLSNLDDVLLMNSWGERAIYYNPNGILKRG
                     VYVLTIKEKDSNHDKGSLVSRPNVYRVNIGLKKETFIEMFGYIPKRPGVGQIVDMDFD
                     FTKLDTIMPHPIYSWMGWICVLSPTEKTFENFKTLIGESYNFAKQKFKKRKNK"
     gene            complement(15632..16231)
                     /locus_tag="KOU88_002453"
     CDS             complement(15632..16231)
                     /locus_tag="KOU88_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212325.1"
                     /translation="MKLKRTLFVGLALVLAIGITACTKNNEKPSENTGKNPNESVNNN
                     EGYMNYYSTSYNDYIAGLNRYSIYDTPESINNQFKDKEYPGNEKYLSDVKAAYKDSRD
                     KIQSFVTSLKKDGKTEDTELKKMNDDLIAEGERLVKDIDKRIEKLDKVSDEDMKKGQN
                     DFIKLVHGTEDVGNDIGSGFRKMIKDMNDRLGITGNNKK"
     gene            16477..17073
                     /locus_tag="KOU88_002454"
     CDS             16477..17073
                     /locus_tag="KOU88_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3793 family protein"
                     /protein_id="HBK3212326.1"
                     /translation="MSCCNSQFCCKNKIESSYIKWLLEVLGPVFLGSKPAEIINISFT
                     DVNREEKINDIYKYLYKCKKIDFIVIDKEKKGLKILFVNKKALSEKLKCKKTVNFLKF
                     LGYKQNTNVNAYLEHLVDKLKSDVFPDEIGIFLGYPLKDVIGFMGYSNYEVSMIKYWK
                     VYGDTKQSEDTYSKFLLHRKKMRKLLDYISVDKIVSCF"
     gene            complement(17171..18130)
                     /locus_tag="KOU88_002455"
     CDS             complement(17171..18130)
                     /locus_tag="KOU88_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NrtA/SsuA/CpmA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK3212327.1"
                     /translation="MTSLIMVLVGTVGCSTTNDKKDEPAKKEASLPKEINLTYVKSPL
                     NVPSILEKKDDLFGKEFKKDNIKVNFHELTTGPEQTQALAAGELDFLHALGGTSAIIA
                     ASNGVGLKITNIYSRSPKGYMLITNNDNIKSIKDLKGKKIVGPKGTILHQLLIAALAK
                     EGYTIDDVEYVNMDIPSAASALESKSADVAMLAGPVALKTINSGAKMIVNGEGLVSGI
                     IVTAVSDDFAEKYPELVKRFMKVHEETLKYMNENKDEVMDVVSKEVGLSLDETKEMYS
                     WYDFSSKITDKDIKELEDTQEFLMSNGMQQKKINIKDMLYNQN"
     gene            complement(18164..18895)
                     /locus_tag="KOU88_002456"
     CDS             complement(18164..18895)
                     /locus_tag="KOU88_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212328.1"
                     /translation="MVRSGFLLENIYKKYLVDNKEHLVLDNISLNISSEEITVILGES
                     GCGKTTLLRILAGLENATSGNIYFFNNDKKCTPKVGMVFQESRLMPWLNVSENILLHT
                     EKDNRNKVDLDKYLKMMKLEKFKNSYPNELSGGMAHRVSIARALSFNPDILLMDEPFA
                     ALDYFTRRKMQKEVVNIHKNTKKGVVFVTHNIEEAMEIAKKIIVFSKNKRIKQFSVED
                     EYNRDLTKNYYINLKKEILRELGEF"
     gene            complement(18888..19658)
                     /locus_tag="KOU88_002457"
     CDS             complement(18888..19658)
                     /locus_tag="KOU88_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212329.1"
                     /translation="MFEKIHKRLKGYYIFLIILILWKIVCVLGIWSSYILPPPEIVLD
                     TFIKMIYDGSIFLNVYASVRRILIGFLISSLMAIPLGVLFGVNKKMYEYFKPLFEFMR
                     STPPLALVPMLILWFGIGEESKIIIIILASFFPIFLNTLKGIKNCDNKLIEVGKSFNL
                     SKKRIFYKIIIPNSMLDIVVGLSLGLGYSFRAIIGAELIAASSGLGYLISDGKDMSRT
                     DVVLVGIFVIGFLGILSDYLFSKIITKFSKGKQVDLNG"
     gene            complement(19743..20453)
                     /locus_tag="KOU88_002458"
     CDS             complement(19743..20453)
                     /locus_tag="KOU88_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIM24 family protein"
                     /protein_id="HBK3212330.1"
                     /translation="MFKFDVTNELMCIARGSGKFFAKKGAMVAFKGNFNFEKLLLGPS
                     NGGGLGRALLGHVQRSLTGEQMPIMVVEGEGEIYLAQNAYHVDVISIDPGDSIYVESE
                     NLLAFSEQLNYSVKLIGSGVISQKGLFTTHLVNKTGQNQDVAIITDGNPLILEGPCCV
                     DPDALVAWTGREPYPKVSKLSWKTFIGQTSGESYHMEFVEPGQIVIIQPSERLSGLKT
                     DSTPSDRMSSGGLRLGID"
     gene            complement(20633..20785)
                     /locus_tag="KOU88_002459"
     CDS             complement(20633..20785)
                     /locus_tag="KOU88_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBK3212331.1"
                     /translation="MATFIIAAIVVVLMALAVMYMVKNSKKNGSSCGCGCSGCSSSKS
                     CHSAKR"
     gene            complement(20811..22967)
                     /gene="feoB"
                     /locus_tag="KOU88_002460"
     CDS             complement(20811..22967)
                     /gene="feoB"
                     /locus_tag="KOU88_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBK3212332.1"
                     /translation="MSIKIGLIGNPNCGKTTMFNGLTGSSQYVGNWPGVTVEKKGGKL
                     KGNKDVEIVDLPGIYSLSPYTLEEVVTRNFMLDDKPDAVINIVDASNIERNLYLTTQV
                     LELGIPTVIALNMMDIVNKNGDKINIKELSEVIGCPVVEVTAVKGQGIMEAAEKAVEL
                     ASSNNKLNFKLPFVDESKDAIEKIEKIIEEKTPYIDVETRWLAIKLFERDENVIQKLD
                     ISKTILNSIEEITRNCEDELDDDSESIITANRYEFISSIISSIIKKNRKGKETVSDKI
                     DKIVTNRILALPIFALIMWGVYYIAVSSLGTIATDWTNDVLFGEIIQGNVSNFLASLN
                     VAEWLQGLVVDGLIGGVGAVLGFVPQIMLLFLLLSILEDCGYMSRVAFIMDRIFRKFG
                     LSGKSFIPMLISSGCGVPGVMSTRTIENDRDRKMTIMLTTFIPCGAKIPIIALFAGAL
                     FGGASWVAPSMYFLGIAMIIICGIILKKTSLFAGEPSPFVMELPQYHIPSAKGVLIHM
                     WDRGKAFIIKAGTIIFVACGVIWFLQSFNWSLQMVDAGDSILASLGNIVAPIFAPLGF
                     GNWQSSVATVTGLVAKENVVGTFGVLFGISDATEQDPTLLASVASMFTVASAFAFMAF
                     NMLCAPCFAAIGAIKREMGSWKWTWITLGFQTLTAYIIALLINQVGSLVLGTGGSIAG
                     AIISIFIAVAVVFVVLTYSNKNMKKEKMGKLSYMKN"
     gene            complement(23067..23288)
                     /locus_tag="KOU88_002461"
     CDS             complement(23067..23288)
                     /locus_tag="KOU88_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBK3212333.1"
                     /translation="MNRLKDIKCGETVKVKKLEGEGATRRRIMDMGITRGVNIFIRKV
                     APLGDPIEVTVRDYELSIRKSDAEKIIVE"
     gene            complement(23301..23513)
                     /locus_tag="KOU88_002462"
     CDS             complement(23301..23513)
                     /locus_tag="KOU88_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBK3212334.1"
                     /translation="MMPLILSNTGEEVVIKKISGSDKTRTFLNSIGFVVGTNVKIVSK
                     IDGNLIIDVKDTRVALDKKMASRIII"
     gene            complement(23834..26731)
                     /locus_tag="KOU88_002463"
     CDS             complement(23834..26731)
                     /locus_tag="KOU88_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3212335.1"
                     /translation="MKAFKKHFLILSLIFLLIISCFNNILCFADESENSKKIRVGYCD
                     DYGIISSSKEHSYTGYGYDYLREISKYTRWEYEFVKGSWEECLDRLEKGEIDLLGPLQ
                     KNDERNKLFNFPKLSSGYEYSALYTKDSNNNMFYEDISSFKGMRVAVLRGNFHNTAFE
                     KYREENNFSVEYIYCNSIDELIESVNEKKADAFVCGSIINAKGMKIVSKFSVEPFYFA
                     TAKDKPNLVKELDYALKELKINDMYYELELYKKYFKREVNNSIAFTRQEMNFIKANPK
                     LTMVYDSEWSPVEYYDKESNSFKGISSDLMSIISKKCGIKFEYIKTKNYNESLDYIKS
                     GKATMLCGSINENDKAKRFNMKLTNPYINIPMIMVGKLDTNLNNDLNIALTSSYKSID
                     SYIEKSFENAKTTSYKSVESCLNAINEGKANLMILSSYQFDELLREGKSENLSVISVL
                     DTSYGMRIGVSNKTDPILVSILNKSIDKITEEELSDCIYSNTIDKPYKVPFGVIFKEY
                     SIQIISFVCILFLIAIKYIIYNKKKKEDYLRKIAYTDPLTGADSIDKFKINSNKLFAK
                     NNPEEYALFYIDVDKFKYINDMFGYDMGNDTLIHISNTIASELKEDEIFARVSADHFV
                     LLIKYKTDDDIKTRLNNIYNKVQILSNPKINYYKLILDCGIYKISKSDNDINTIMDRA
                     NTARKTIKGGHKNSFAFYDKEMHKKILKEKEIENSMVDALNNGEFIVYFQPKYSLSDY
                     QIIGAEALVRWDNPQKGLIPPIEFIPVFERNGFIVNIDFYVFEEVCKKIREWMDEGQK
                     VVPISVNLSRMHFVNSNFIEEFKLIVDKYKIPTRLIELELTETAVLDNIEGLLDTMNN
                     LKEKGFVISMDDFGTGYSSLNLLKELPVDILKLDRAFFTEKDESNNEKIVISNVIKMA
                     KELKMKVISEGVETISQVEFLKQIGCDMVQGYLFSKPMPVKEFEKIAFKKE"
     gene            complement(27058..27666)
                     /locus_tag="KOU88_002464"
     CDS             complement(27058..27666)
                     /locus_tag="KOU88_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBK3212336.1"
                     /translation="MVDNLIKYIHKSDVAIVVLHEIYGINSFIEDVCQKYYKYGYDVF
                     CPELLGEKRVFPYSKVQEAYDFFINNVGFDIYKKVEKLINDLKSEYKYVFVAGYSVGA
                     TIAWRCSEDSFCDGIICCYGSRIRDYMDVIPKCPTLLVFAKHDSFDVDSISCQLSRKQ
                     NIQIEILDANHGFIDRYSNNYSDIQTKVFTIKEKSFLSKCLA"
     gene            complement(27926..28471)
                     /locus_tag="KOU88_002465"
     CDS             complement(27926..28471)
                     /locus_tag="KOU88_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH peroxidase"
                     /protein_id="HBK3212337.1"
                     /translation="MKKFVCTVCGYIHEGDTAPAQCPVCKVGADKFEEMKGEKNWADE
                     HRIGVAQGVDEEIIEGLRANFVGECTEVGMYLAMSRQADREGYPEVGEAYKRIALEEA
                     EHAAKFAELLGEVVVADTKENLRVRVDAEYGATDGKLKLAKKAKELGLDAIHDTVHEM
                     CKDEARHGKAFLGLLNRYFGK"
     gene            complement(28589..30412)
                     /locus_tag="KOU88_002466"
     CDS             complement(28589..30412)
                     /locus_tag="KOU88_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212338.1"
                     /translation="MNLSTGNQKVSRLKKKEKPKDFKKTFKRIFMYFKKDKKITRFIF
                     LLVIIDSIISTVIPYTIGKVVDIIDINTYSKSIFLKGIIILLSFYIIEFSVKLSKGIC
                     TARLSQSIVREMRSNLFLKFKNLPITFFDKSSTGDIMSRVTNDVDNISTGISNSLVQL
                     ITGILNILMTFIMMFVLSPILTFCSVILIPIVMFVSNFIAKRTRVFFKQQQVELGKLN
                     AHIEEMVSNINVVKSFNYERKSVNDFKEVNDRLLNISLKSQIYTSLLMPIMNVISNIG
                     FATICIIGGILASKDIITIGVIASFLSYVRQFTRPLNELANLFNTLLSAIAGCERVFE
                     IIDEQEEQEVHNMFKSEINDNKDGNLNSHFVKGEIELKDVSFSYDSKKKILDNINLKI
                     KAGTSNAIIGETGSGKTTIINLITNFYHIDEGSIFLDGKDIYSINRNYLRTCFGVVPQ
                     EGYIFNDTVMENIRYGNLEATDEEVIYASKIANAHKFIVKMREGYSTILSDRGEDLSE
                     GQKQLISIARAVLKNAPILILDEATSNIDIATEAKIQEAINNLTYGKTSIIIAHRLST
                     ISNCDNIIVLENGRIVESGNHKELIKLKGHYYRNILLTQGK"
     gene            complement(30425..32200)
                     /locus_tag="KOU88_002467"
     CDS             complement(30425..32200)
                     /locus_tag="KOU88_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212339.1"
                     /translation="MRYFKKYIKKYIVLFLTAVFFLTLEAFCDLAQPTIMAKIIDIGV
                     SNKNLDYILSTGAIMIGITFLGAIFAIIRSVISARVSQHFSYDLRQDVFEKINTYSLK
                     QIDKFGRASLITRITNDINQMQQFVNGMMRVFIKSPIMCIGSLIIAIKLNLKMSIIIL
                     IAVLIIFIIILLNMKIGYRLFKNVQESTDKVNSKLRQFLSGIKVVKLFCRYDYENQSF
                     EELNDELFKNSRKATTMMSFFRPTITIIINVSIIIILLIGRHLIYSGEIKIGIIVAYV
                     NYMTRILTSLIMISHVFNVFVRAKASYERISEVLVDENEEVIEREESLDVGEKDLKFV
                     NCDIIFENVDFSYNKNTDEKILKNVSFKIEEGQNIGVIGQTGSGKTSLVNLIQKLYII
                     DKGDIKIGGRSIYSISEESLRERIGVVFQNSSVFGKSILENVVMGNRDICKEDVVKSC
                     EIANANQFITKLENTYDEVLFQRGKNLSGGQRQRITIARAIAKKPQILILDDCFSAMD
                     INTETIIRKNIKEYISNLREKESKKCTVITISQKISSIIDCDKILVLDEGEVVGFATH
                     EDLLVSSPIYKKIFALQNLVSEDVN"
     gene            32493..34721
                     /locus_tag="KOU88_002468"
     CDS             32493..34721
                     /locus_tag="KOU88_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBK3212340.1"
                     /translation="MRHLKKTNSLKEILNWNNIKNLRPSKGLKNILEIFKSDLKDIRG
                     NYAVLVIVLGLAFLPSLYAWFNIKASWDPYGSTANMLVAVTNEDKGNEIAGQKINVGD
                     QLIEQLKDNKSLGWQFVDEKTALEGVKKGTYYASLKIPKNFTKDLTSLITDDVKKGEI
                     IYTVNEKINAVAPKITDKGASTIQLQVNQTIVKTVSEIVLGISNGVGAGIEHSLPKLT
                     KVENSLIDLQKRFDHINKTVDLASDATSKLSDTVKDIKSDLPTIKKTLNDTKLLSSDL
                     KKFLEDTNDNLDELSPLIKSDLNLMVDLSSSASSLTLNLIDAVNSGSEDVPKLIDNLS
                     EKLSNLQSLNDTLVDFLTKLNQLTSNNRLDDVIDNLEDSSNKIDSSISTLNDIKNKVI
                     SGQQPSISALNNVLSLSNGIGRINLNILNNFDSKISKPINSIFANSIKVANDIITVLD
                     KAEAKLPKVEEILTTSLKLSGNAQESISLIRERLPLAKGMLDDLIDTLSKISNGEDMK
                     KLVSLLESDILTKSNFLKEPVEVKTEKLYPIENYGSAMTPFYSVLSTWVGILLISALL
                     STSVHGNYKPYEIYFGRGLTFLSIALVQGFIIGTGDILLLGVTAKHPILLIVLLMFTS
                     MVFNFIVYSLVSVFGNVGKAIAIVLLVVQIGSSGGTFPIQVTPTFFQRINPIMPFTYA
                     IGATREAVGGIYAPNLTKDILVLLLFMILSICLNVLLKGPINRVIKPFNDKFGDSNLT
                     GH"
     gene            complement(34959..35258)
                     /locus_tag="KOU88_002469"
     CDS             complement(34959..35258)
                     /locus_tag="KOU88_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBK3212341.1"
                     /translation="MYKNINKKQLKEMMKNEKDVLLLDVRTKDEFKEYKIENAINISL
                     QELINNIDEIYDYKDKKVVVYCRSGHRSVTACNLLAEEGFEHLYNLNSGIIDYMS"
     gene            35465..38506
                     /locus_tag="KOU88_002470"
     CDS             35465..38506
                     /locus_tag="KOU88_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp20"
                     /protein_id="HBK3212342.1"
                     /translation="MFKQRLSKLLSSTLVLSMLFTAAPNITFADNTKDNSEKYQSSDI
                     ELHDYSKNAESYTKTKALAKEKIQTLLSKYGAVSAQYALIDNGKIEISGNGGVYSKQD
                     NKNLNKDNMYSIASISKMFTTTAVMKLVDDGKLNLDTPVVKYIPEFKMADDRYKEITP
                     RMLLNHSSGLMGSSFKNTILLADNDSYGHDNFLKELQKQRLKAKPGAFSVYCNDGFTL
                     AEILVERVSGMSFTNFLDKYINNPLNLQNTKTPENSFDSSKLAKAYVPYWEDAVPQDN
                     LNAIGAGGLYSSAENLCTFAQTFMKNSNGILSPASVKAMENKEYLNGLWPEGEDSILG
                     YGLGWDCVNTYPFNQYNLKALTKGGDSLLFHSNLIVLPDENMAVAVLSSGGSSQLNEI
                     IGQEILLSALKEKGKIKEIKPDKTFSKPQQVKMPSSLKENSGLYASSNMIKVDVNDNG
                     TLTVSSPYIENGPEDKYVYIGQDRFVSEKGNSCLKFVKEKNNITYLNMSSYDDVPGLG
                     QTASLYYVAQKIDDNNISNSVKEAWKKRNGKDYYLVDEKYTSQSYMFGSVKATLALSD
                     ETPGYIVNTKIMDENNSNAFIEIPGVIGRDLSDIKLHKENGTEYLSFGTLTYVSEDSI
                     TNLPAEKSFTCELESNGYAKWYKIGDDLANKKIEVNLPQNSSFAVYDDKGVPVNYSLV
                     TKNNRVRLPKGGVIVFLGSPNARFEVTYQDEVNASALTGTDRYETSIKISQAGWENAE
                     NAVLINDSAIADALAATPFAYKKNAPILLTGSSQINEKTLAELKRLKVKNVYVVGGEA
                     SINEKSLDTIKSNNISVSRISGSDRYQTSMNIAKELNNISNISKISVVNGEKGLADAV
                     SIGAVSAQNDMPIILTNENSNITEINNLFKNKKIDKSYVIGGEYTVSKNIESKLQNPQ
                     RISGSTRNETNAKVIKEFYKDSKIDNLYVAKNGMNKQDDLIDGLSVGVLAGKTKSPVM
                     LVGNSLDYNQKELFKTMRFKSVTQIGGNGNENSFKQIKEIA"
     gene            complement(38667..39941)
                     /locus_tag="KOU88_002471"
     CDS             complement(38667..39941)
                     /locus_tag="KOU88_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBK3212343.1"
                     /translation="MITISHITAKNMYKSLEERINKFPQGAPPSDTLYKILNVLYTEQ
                     EAKLVAQLPIKPFRVKTAAKIWSVSESEAYRVLDKLASKALILDIEDNKGKKYIMPPP
                     MAGFFEFAMMRTRHDIDQKLLAELYYQYMNVEEDFIKDLFYSTETKLGRVYVQEEVLT
                     NDNEVSILDYERATHIIDESTHIGISMCYCRHRMQHVGKACDAPMDICMTFDNVANSL
                     INNKFARRVDKIECKELLHQAYEHNLVQCGENVRKGVTFICNCCGCCCEAMVAAKRFG
                     NLHPVQTTSFIPNINHENCVKCGKCITACPIDAISKVKEDGKEYIKIDEDRCLGCGVC
                     VRNCHKNSIMLLKRDEKIITPANSVHRAVLMAIEKGQLQNLIFDNNALASHRAMGAIL
                     SAILKLEPAKKILANKQLKSVYLDKLLSMNDK"
     gene            complement(40162..42723)
                     /locus_tag="KOU88_002472"
     CDS             complement(40162..42723)
                     /locus_tag="KOU88_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212344.1"
                     /translation="MNLYTSLTIRYLKQNKRRTIVTIIGIILSTALICGIGNIFESFM
                     DYQMRETIKNDGSFHVTFYDVNRRNVEYVTKSAEIEKHAFTKQLGYSKLENSENAILS
                     IKQYDKNAINGYKVSIKEGRFPAKEGEIVLSESIINLIDDKLKIGDKITLKVGDMFDS
                     SKKKIDSMTFHEGDYIANEKDRTFKVVGIIEKPGFERYNGIATAIAYFNPMNNYNDTI
                     NVSVAVRNPKDVYKISNKISKNIYSNKDKEAVSDMIKYNEHLLRLQGASKYSNINSSI
                     KSIIIAVTILVIICTIATVYNSFSISINERKKQFGILNSIGATSSQIKRLVFIEGIII
                     SLIGIPIGLISGTVAIDLLFKIINKYFTESVVTKMSLQIVYNPIIIIVSIIIVLFTIF
                     ISILLPAISASNISPLNVIKNTGEYKVGKIKSSRLIKMIFKTEGVLAYKNIRRNRKKF
                     IITLFSLMVSIIIFISFSGFTLLLLRGEEIRNSQRKYDLYLTAKNTARSVEDTISELE
                     DIDGIKNFELATGQYVSIRVSENKINKSKEDLIRKYYQKYKIGDSYEYDFSNNELIFP
                     GDFAVKNKINNLVQGSFNKERAIEENGVILVRKSAFEENGKKGVVELTNYKVGDTVNC
                     EYLDENALSKKVKVKILAITDEERLGLGYQNMGLQFITYDEVAKNLNLKLSKSLIFID
                     SGGSIKTKKEIEALANKNNFNFYDESASNESEKQDLKVIKIFVYGFIVVISLVSVTNI
                     LNTVSTSINLRKRELAVIQSIGVTPKGFRKMIYLESFIYGILSLLFGIPISIGIILIM
                     NKLISGVIEFSPIIPWTAIVICIVSVFIITFIAGYIPMSKLNKENIIDNIRRESI"
     gene            complement(42724..43401)
                     /locus_tag="KOU88_002473"
     CDS             complement(42724..43401)
                     /locus_tag="KOU88_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212345.1"
                     /translation="MEILRVENITKSYGKNETKVDAIKNVSLSVEKGTFIAITGPSGS
                     GKSTLLHLLGGVDRPTSGKVYINDVDIYNLKTKDLAIFRRRNIGLIYQFYNLIPVLNV
                     KENILLPAELDNRDIDREYFDDLMKTLGLIDREKHLPNQLSGGQQQRTSIGRALINRP
                     SIILADEPTGNLDSKNSKEILELLKLSVKKYNQTLIMITHDKNMALQADRIISIEDGI
                     IKSDEVM"
     gene            complement(43481..>44025)
                     /locus_tag="KOU88_002474"
     CDS             complement(43481..>44025)
                     /locus_tag="KOU88_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3212346.1"
                     /translation="NQLNRMDWLIKSMLKLSKVEAKVINFKKDKVKFSELIHRAMLSM
                     KIPMEIKNQKLIIEGNDNVSYIGDIDWSVEALVNIIKNCVEHTPEFGNIIITYKENPL
                     FSELIIKDEGEGIDKKDIPHVFKRFYRGRSSSKEDSVGIGLAMSKSIIESQNGDIYVN
                     SEKGKGTEFHIIFHKMYDSD"
BASE COUNT        14789 a         7287 c         4699 g        17250 t
ORIGIN      
        1 ttgaccacaa tacataatgt ttccatttgt aaagttagtt ttatatgaaa atctattaat
       61 tttctttgat ttaaatttag gaaatcctgt tttttcttta aagaattttt tatatgcatt
      121 atctaaatct tttaaggcgt tttgtagtga aaatttgtca ggttccttaa gccattttaa
      181 ttcttttttt aaattggtca aatcagaact acactgttta taagtaaaag tttctttatc
      241 gtttttataa acatctattc ttttagcaag atacttatta tatacaaatc tacaacatcc
      301 aaaagttttg ttaattaact cttgttgttt tttatttgga tacattctaa acttataagc
      361 ttttttcact gctatcacct cactttaatt gttttttgat acacttttta atgattttat
      421 cacattttat cacatttaat atattatata atgctgtggt aaacaattta ttaatcacct
      481 ataataatgt taacaaatgt aattatttaa aacaattatt tagaaggttt tatatttaat
      541 tttaaataac atatttaaga accgtaagtc ttaactttta tcatttttga ggttgtcgtt
      601 cacataagtt cgctactacc tatgcagttc tcttatgaac ttcttacact ttcatgtaag
      661 cacagactat atcttatcct tcagcattat ccgttaaggt ctacccactt ccactaccaa
      721 tagcttgtag tgtacttccc tcaagaggaa tagtcgttga agtttctcct attcggagtt
      781 tacctgctga ttgcccattt taaagtactt aggatttaac cttataccat ctaaccaatt
      841 ttttctactt tcgtaacttt cacacttagg tttatttcat ccttatgttt tagtttgatt
      901 agctttaggg gtttccagca attcaagtag tattggatag gttctatcct atctctacat
      961 ataggtttcc ctatatgctg actattttag ctactaactc atgactaaag tcacgagtgt
     1021 gcgtagctat tttttaatca atattttagt aaattttacg gtaagtaaaa acctctctcc
     1081 ttcaaatcct atagcaaata tacttacaag ttgctttgag aaaataactc ctaatatagc
     1141 tacaactatg catataccaa ctattatatt taaaacattg tttaaaaact ttagtgcttg
     1201 cttttcacct tgtttactac ttatatcttg atacattgga ataaaagtag taactatagc
     1261 agtacctatt gctgcaaata taatatttgg tatattcata gctgttaaat aactctctgt
     1321 atataagcct gtaccataaa ttgatgataa tactaattct ctacccattc caagaatctt
     1381 agagattata gtaactatca tcaaataaaa agttgcttta gctaccttgc tcattttatc
     1441 actccacttc taacatacct ctttttaatc aagtaaaatt tagctcatta gatataattc
     1501 tatcaactaa tttgtcttgc ttagccctat caaaatataa ttaacaccta tttcttaata
     1561 tatcacaaac tacattattc ttcatatttt tttatttctc caataagttt tacatctttc
     1621 ctatataaat tgtatagctt caattatatt caaagaaatg gagttgctac ccgataactt
     1681 taaaagtaaa aaacagattt tattatcttt ttaaactata ttctaacata ttttgtccat
     1741 attgagaaat tttactaaac tattatgtac tttattaaat aaataaaata acagcacacc
     1801 tataaaatac aagtgtgctg ttcataaaca gattttataa aaaaataatt cctaagtaga
     1861 gattaacatg ctttctcata ctctcatata taatgtgtat aaaaatatta ataaaaatgc
     1921 tttaattgtt ttaacttact tggatgtctt aattttctta ttgctttagc ttctatctgt
     1981 cttattcgtt ctctggtaac tccaaatacc tttccaatct gttctaatgt tttagggtca
     2041 tcatcatcaa ttccaaatct cattcttaaa acttgctgtt cttgctctcc aagacctgta
     2101 agtagttctt ctatcttttc ttttaaatta tgctgttcaa cttcgtgtat tacaacatct
     2161 ttaaaatcag catctgatgg tataaattca actaaactac tatcctcatc ttcttttaat
     2221 ggagtatcca aagatacaac atttttatct cttcttaata attccaacac tttgtcaact
     2281 tctaagccac atgcatctgc aatctcatct atagttggct ctcttaataa tacatttaaa
     2341 agttcttgtt tctttttctt tacaaaattt attctctgat gaagatgtat aggtatccta
     2401 atagtatttt cgcaatcgtc gatatatctt gttatacttt gttttatcca ccaagttgca
     2461 taagtgctaa atttgtatcc ttttttataa tcgtactttt ctacagcttt tataagtcct
     2521 atatttcctg cttgaattaa atccaacata tcaatactat ctcttttata tctctttgct
     2581 atgctcacta ccaacctata atttgaattt ataaattttt cttttgctac tgaagatgag
     2641 ttgattattt ccttagccag ctctacctct tctcctgctg acaacatttt gtattcctct
     2701 atttccttta aatacatttt catcgcattt gatacatttg atgaacccac acaaatataa
     2761 ttttcataat tattttcttt tttagtatcc ataatcaaac cccttctatt catagaattt
     2821 gctaaaacaa aaataaataa tttaaaccta cataatctac aattacataa tatcccattc
     2881 tttaaatgaa ttgttttgta tattatgtat acaaatttat aaaaactata cctataatat
     2941 tattctactt ctaacagcaa tatcctcctt atatatataa tttattttat tatatgttgt
     3001 tatattctta gttttttgaa tgatatatgt ctaaaaaaag actgtttact aaacagtctt
     3061 tttttatata tatgctcaat atttaatttt catgatgatg attacatcca catccacaat
     3121 tttcatcatg gtgatgatgt tcttctaaat cttttgcctg ttgttccatt tcatgaaact
     3181 cttttaccat tatatcataa gttggaagag ctgcctcagt atcgtattct tcccctctcc
     3241 aatcagcgta catcatagca tctccattag ttaaaaccaa tctacctgac atagttatat
     3301 tatccacttc ttctaaaaat tctatttgtt tttgtaaaac ttctccttct aactccacat
     3361 cttcatctaa acattgcact atcattacag gtgcataata atcttcttca tctttaacat
     3421 ttacaacaat atctaaaatt ccttctgcac cttcttcaaa ttctgccaac tcaacatttg
     3481 tatcaatcat atcttgaggt actaataaat cttctattaa atattttatt actctatctt
     3541 ttactaattc ttttgacatt tatttttctc cttccgattc tataacatta tcataatcat
     3601 ttctatatta tagtatacta cattaattgt tttttcaatc tcttacaaaa attatttttt
     3661 tattatcttc cttatattcc cttttttatt acaaagttgt aatcgcattg atttaaaaaa
     3721 tagtttatat ttagtataat agaaatgtag cacatatttt tattcaatat attaataaaa
     3781 aaatatattg aaaatgtaat gtatgttaaa tctaggagga atattatgaa gtttaaaaaa
     3841 caaattagtt ctattgttgt gtctactatg cttgtacttg ggagtatgaa cctttcttat
     3901 gcagacggta caaatgtagt tacacttgga gctaacttat cagagtctca aaagcagcaa
     3961 atgcttaatt actttggagt aaaaaaagac caagtcttag ttttagatgt aacaaatgca
     4021 gaagaaagac agtatttaca aggtgttgca acagagggtc aacttggaaa agttactatc
     4081 tcttgctcat acgttgaacc tactaaaaaa ggaaatggaa ttaatgttaa aacagcaaac
     4141 ttaacttggg taactagttc aatgattgct tcaaccctta caacagctgg tcttgaagat
     4201 gcaaatgtta ttgctgctgc tccatatcct gtaagtggta ctggagcatt gacaggaatc
     4261 atgaaagcat ttgaggatgc ttcaggaaag aaacttgatg aaactaagaa agaaattgct
     4321 tctgaagaat tggtagttac aggtgactta ggagatgata tagggcaaga aaaagcaaca
     4381 ggtgtaatga atgatataaa aacagaaatt gtaaagaatg gtacaaaaga taccaatcaa
     4441 atagcaaata caataaataa tgttgtaaat aattacaata ttactattac accagaacaa
     4501 aaagaacaaa ttaaaggtgt aatgaaaaaa atagctgacc aaaattacga ttacaatagc
     4561 atgaaaaata cactagataa tgtatcagat aatgtaaatg aacaattaaa gaaattaggt
     4621 gaaagtgtta agggttctgg tatactagat actattggtg gatggtttag tggaatagga
     4681 gactggttct ctggtttatt ctcaggcgga gataaaaaag atttgggaat cttaaataac
     4741 actaatgatg agtctcttgg ctctgatgct gtaataaatt ctacagaagg tgttcaaata
     4801 aatccacaaa ataatactaa ttctaacaat gatagtgata caaatagctc aaaaaatgat
     4861 acttcaagta ataatgaaaa taacgatagt tctcaaacaa atgaaaacaa cacaacaaat
     4921 aattcagaaa atcaatcaaa taataatgac tcagttggtt tctttgaaaa aataaaaaat
     4981 tggctttcag gcttatttta gaaattaaac aaataaaaag aattgcctaa aatggaaatt
     5041 ttctataaaa ggcaattctc tttatttaca ataaattttt attactcact cattttttta
     5101 gatttttcta tacatgcaca tattgctttt atcacagaag ctctaaaacc ttcttcttca
     5161 agtactttaa ctgcttctat agtagttcca ccaggtgaac ataccatatc ttttaattca
     5221 ccaggatgtt ttcctgtctc aagtaccatt tttgcagaac ccataacagc ctgtgatgca
     5281 aacttatatg cttgtggtct tggcattcct gcaattactg ctgcatctgc tatagcttct
     5341 ataaataaaa atacatatgc tggtgcagaa ccacttgcac caattacagc ttctataaga
     5401 tactctggta ctacctcagt atttccaaaa gaattaaata cttctgtaac tgcttctaag
     5461 tcttctttgt ttatattttt atttatagaa agagaagaca tggcttcatt tacaagagct
     5521 ggagtatttg gcatagttct aactattttt ttatcttctc ctataataga ctctatatct
     5581 tttatagatt ttcctgctgc tattgtaact ataattttat tgtcatctat aaagtctttt
     5641 atctcttcca aaatatcatc atatatatct ggtttaacag ctacaattac tatatcagag
     5701 gttctagtta cttccttcga gtcttttgta gtatttattc caaaatttgc atctattcta
     5761 tcgagagttc cttgactata tgctgatgct ataaccatat taggttcaac taattttgaa
     5821 tttactattc cccctatcat agcgcttgcc atatttcctg cacctatgaa tccaattttt
     5881 ttcactttag tacctcctta ttgactaata gtaatcgtta aaatttaagc ttctttaact
     5941 gcatcagact tttcaaatgg atttggtata cttactacca aaattttcac taccttatta
     6001 gtatagttga cccaattatg attgttcttt tcactattat agtgtattgt gtctcctgga
     6061 tacatttcta tttgttcatc tcccaaaaac actgtaagag taccctctaa tacatacaca
     6121 aattcctcac cttcatgtac gtaacaacaa atttcctcac tactcttact tggaagaatt
     6181 tcaattaatc ttggtagcat tgttttttcc tttaaactag atgataaatg ataatgtata
     6241 aatgttgagt tttctacatc aaatacttct ttttcataac ttcttaatac agctctttta
     6301 tgctcttttg gcttcataaa aaagtaagtt aattctacat ctagtacact tgctattttt
     6361 cctaaggaat ctgttgccac acttgttaat cctctttcaa gttgtgataa aaaaccaatt
     6421 gacaagtttg ttttttcact catatccttc agcgtcattt gcttttgagt tctgagttgc
     6481 tttatttttg ctcctatgtc cttattcaaa accatcaccc ctaaataatt ttaatttttt
     6541 cataatataa atacaaaaat ataaatatag gtactgaacc tatctttatt tcatttaaaa
     6601 aaatttttat aagtattact ataatttatc aatctttttt tgtctacatt tttacgatta
     6661 tttacgattt atttttcaca tatgtatatt taatcttgcc aactaaagat acatttttta
     6721 taagcattta ctctttatat aataaaactt aagttgttca tgtagtcttc ttctggttta
     6781 attattaaaa tttcaaatta tattattatt tctacacatt attacatcct ttagtacaat
     6841 tataacataa ttttacaatt taatgatatc tattcaatgt ctttttttac tctacaacat
     6901 attttatttt agagtttaat actatatata ttttttatat acagccttgt cattttttag
     6961 attgtcaaga gttattgaag tattttatgt agatttagat tctatttcct aatttctcat
     7021 ttaacaagaa ttgcttatga taaaaaataa tatcatctca ataagattct tgtaaatata
     7081 tctatattct aaatataatt tctttttttg tcaaaatttc ttcattcttt aataattaat
     7141 ttattactta taaaataaac taattatcta tacaaatttt ataattttta ataaaataca
     7201 caaaaaaatt aatttttata gctcatttcg ccaaaatata tctttcttta tatcattaaa
     7261 ataattataa atttattaaa tatgtttgta attctataaa gttattttta tcaaactaaa
     7321 aattctataa aaaaataaga tacataccta taaaatacct tcctatagat acatatctta
     7381 cctatataaa aacttattct atataaaaac gccataaaaa atcttttgct tcttctgcat
     7441 aatctatatt tatacgttta ctagttttta tatctaactc atctttacta aatacttttt
     7501 ttcctttatc atcataataa aaatcactta tatataattc ttcacccatt atactcttac
     7561 tatttagact tctatctatt tttaaagctt tgcaaagttt tcctggtccg ttagtaatat
     7621 tttttacttg atatttactc aactcagtgt aagctttgtt gtatctattc atagatatct
     7681 catctaaaga agttatcggc tctacccctc ttattaatac acactctggc acattttcta
     7741 tatttgcaga taaattcaag caattataca taccataaat taaataaaca tatatatgtc
     7801 caccatctaa atataatggc ttagttctat ctgtcttttt attgccatat acatgtgctc
     7861 ctttatcatt tacacccatg tatgcttctg tctctatgat tttggtaaca attactttat
     7921 tttcatattt ccttattaga tatttaccta atattgattt ggctaaatca attccatttt
     7981 ttctaaaaaa atccttttcc aaaatttcac ctcataaaat ttatttaaaa cgcatcaaat
     8041 acaactaaag taataaataa aattaactct tattaatgtg atatatataa acaataaatt
     8101 tagacattta ttatttatat atatcaaaaa attctatctc aaacttttca atattatcat
     8161 tgtaatttga attatcatat acttcttcaa caacctcttt aattgggaat ataactttta
     8221 cattagttcc ttctcctacc ttactatcta tgtaaatctt cccattttga atttcaatca
     8281 atgattttgt aaggcataaa cctataccac ttccaaattc atttgatata ccactgtttt
     8341 caatttgttt aaatcgatta aatatatcat ttaatttttc tttgtctatg cccaccccag
     8401 tatcttttat aattatctct actgtttcgt cttttttata tatacctaca aggatttctc
     8461 ctccttctaa agtaaatttt atagcatttg ataatatatt tagtattatt ctttctatcg
     8521 attctgggtc aagccctacc ataacagttt cttcatctgt atcaaaaatt aaatctattc
     8581 ctttagactt agcataacta ctaatagatg taactattct ttctgttatg tcaataatat
     8641 caaaattaac tgctttaatc ttatatatgt ctgacttaac ttgagaaata tttattatat
     8701 tatctattaa tctcaataat ctaaacatat tttgtttagt tatttttata tgttctttta
     8761 gtatatcctg aaaatcaatt atttttcctt ttttataaag gttttcaata agttgaactg
     8821 aactatatat attatttaaa ggtgtcttaa gttcatgaga tatattagca taaaactcca
     8881 tcttcatttg gtcatactgt ctttgtttta ttaatgcttt tttaagtctt tcagactctc
     8941 tttgcacact taaatcttta ataattctca ctctacttct tttctgtcca aagtataatg
     9001 ttcttgatat catttttact tctttaatgt gattattttc atttactata tggatactct
     9061 tctctctttc tcctatattt aaattgttta tgtatttttt tactaatata tttctatatt
     9121 tttgtgttgt aactcctaat acatcactag aaattccgaa caactctcta aaggttctat
     9181 ttgtatatag tactcttgat gtacttaaat cctcaagaaa aatagcctct ggtataacat
     9241 caagtaattt ttcatatatt attttttgtt catttactgt tctaagaata tttatctctt
     9301 tagttatatc tctaaatgta agcaatttaa agagtttatt atctgaccaa tagtctccaa
     9361 ctctaacttc ttcaacatgt tcttcacctt ctgagtcaga catcacaaaa ttaactatac
     9421 agtttgctgt gtcattgtaa cttactattt cagctttctt ttcttgtgtt agatttaatc
     9481 ttttaaattc cctattgtca aagaaatcta tgttaaaagt ttcaaaatat tgttctaatg
     9541 tcatatcgac taaatcactt gaaacacatt taaaactctt ttcatatttt ttatttatac
     9601 ttattacctt attcttcttt atgccaccct cagcacttct tacaagtata ggagatggaa
     9661 tatttagtat aatgttttca tagtctttat ttatatttct tatttcttca tctattttga
     9721 tttcatttgt aatatcattt aaacttatta agtaattgct ttcatcttta ttattactta
     9781 aacttaacaa ataaatttta tcatttaact ctaccagttt atcaattata cttatatcgt
     9841 tatcaaattt cttcaatttt tcagcaactt tttcatcttc ctttataaaa gttaatattt
     9901 tataataatt attcatatcc tttgaaaatt catctttaaa tttattattt gtgtaactta
     9961 tattaaaatc atagtctgtt actatccata catttggtat tgtatccaga gcttgtctaa
    10021 gtaattcttt tctctggtct atgtagtttt ttaatgttct ttgtataatc atatcctttt
    10081 ctattgctaa atttatcttt cctaattgct ctgacttttt acttaatttt ttattgattg
    10141 aatcaagttc ataatatgga tacactactc tattattaag actgtataca tatacataat
    10201 aagtatggtt acataatagt aaatatatta ctcctattaa tctatctgaa tctactatat
    10261 taatcttaga aattgctaca aaacatataa tagttgtaaa aaaaacaaaa tatgttaaat
    10321 cttttattaa cttatagtgc tcaatgttac tatcaagttt attcaacaaa tatagtaaat
    10381 taaacataga tatacaaata ttaattaata taataatcat attccagtta atatcactaa
    10441 aaatatttct tataaagtaa tctaatatca caaaagcact ataaaaaatt agtattgggc
    10501 ttattcttag tttttttact ttagaaatgg ttaagtatat aaaagtagac atattaatta
    10561 tgcttaagtt aagcaataca atttggaatt tttgaatttt taaatttact actcctaaaa
    10621 tacttacaaa aactaataca agacacccta ctttcaatat atttataaat tcatctgttt
    10681 taaagctact tatataaact atagaatatc caaatatcca aagtaaaatt attctataca
    10741 tatttataga aactgtatac aaatttatat ttaaaagtgc aataaccaaa aataacccat
    10801 tagctagtat atagacctta ttcttactta aagttccttt agattccata ttccccacca
    10861 cttcttcatt tttatatagt tttacctata aatatgttac cacaattctt ccaaaaaatt
    10921 tgtcactttc tagttataaa aaaaaatgag taaatatttt taattttact cattttgtag
    10981 attttgtata ttcagtttaa aaagctggaa ctatacttcc tttatattca tcttgtataa
    11041 attttttaac ttctttacta ttcatagcct ctgataaagc cttaatctta tcactatctt
    11101 tattattttc tctacaagct attatattta catatggaga atcacttgat tctattacta
    11161 ttgcatcctt agtaggattt aagttagctg ttaaagcata attagaattt attactgctc
    11221 cgtcaacatc ttttaatact gttggtaatt gctctgcatt catttctttt attactatat
    11281 ttttaggatt tttagttata tcttttttag ttataagctc tccatctttt acttctatca
    11341 atttattttt tgctaataat ttaagtgctc tagctccatt agttgcatca tttggcacag
    11401 ctataacagc tccatctttt aattcatcta atgacttaac tttttctgaa tagaatccca
    11461 ttggctctat atgaacttta gatgtataag taagtttata tcctttctcc ttcacagttt
    11521 cctctaaaaa tggaatatgt tgaaagaagt tagcatccaa agacccttca tctaaagctg
    11581 tatttggaag tacataatca tcaaatattt ttacttctaa atcatatcct ttttctttta
    11641 acaaaggttt tgcaacttcc aatatctttg catgtggatt tgatgaagct cctactagta
    11701 tttttttatc ctctttgttt gaacaaccta ctgctgatat tgctattgct gacaccaatg
    11761 ctactgataa taatttcttt aatttcattt ttactccccc tctttaaaat gtttataatt
    11821 tatttatttt agtttcttat aagccagatt tcctactccc tggattatct gaactaatat
    11881 tataagtgct attacagtat ataccattac tgctgtatca aatctttgat atccataaat
    11941 aagtgctata ttacctaatc ctccagctcc tactgcacct gccatagctg tataaccaag
    12001 tatagatatt attgataatg taattccaga tactattgaa ggcatagctt cctttatcat
    12061 aactttaaat actatttgtc tttttgtagc tccaaaagat tttgctgctt ctatcaatcc
    12121 tttatcaact tcatttaatg agctttctat aattctagcg ataaacggtg ctgccccaat
    12181 agttattggc actattgcag cagtttcccc tatacttgtt ccaacgatta atctagttat
    12241 tggaatcatt gcaactataa gtatcataaa tgggaaactt ctaaatatat ttactataaa
    12301 tcctaatgca ctatttattg tgctatttgg ttttaatcca tctggttttg taactactaa
    12361 tatgattgct aatataaatc ctaatattgt tgccactata gttggtacta taaccatata
    12421 caaagtttgt aacaatgcat ttggaaatag tgttgttaaa aagtcaatta aactattcat
    12481 ttatcatttc ctcccatctt atgcccttac tagttagata ttgttttact tgctctccac
    12541 ttttatctga aatgtttata ataagtgaac ctaaaatatc atctttaaat tgttctaatt
    12601 tcccaaatat tatagacaca tctatattta gttctcttgc catagtcgta ataatagctt
    12661 cattagaaat atctttaggg aatagtatct ttatatttgt tccttttggc aatattatac
    12721 tttcttcacc tattaatttt ctaagtcctt tagtatttct taagaatatt tcttctgtat
    12781 ctcctacctc taatacttct ccattttcca ttattgctac tcttccacaa atctgcttta
    12841 taacttccat ttgatgagtt acaactatta ttgttattcc caatttttta tttatatctt
    12901 caagcaatga aagaattgac tttgtagtat ttgggtctaa tgctgaagtt gcttcatcac
    12961 aaagaagtac ttgtggattt agtgctaaag ctctagcaat tgcaaccctt tgtttttgtc
    13021 cgccacttag atttctgggt ttatcatttt tcttttcaga tattccaact acttctaata
    13081 actctaaaac tcttttttta atttctgcct ttgagtatcc aaaacattct aatggcaatg
    13141 ctacattatc aaatacagtt tttctttcaa gcaatgaaaa gtgttgaaaa atcattccta
    13201 actcttttct taaatctctc atttgctttt cattcaatga ctttacttct ttatcagaaa
    13261 caagtacact gccttcttgg tattcttcta atccgtttat acatctcagt agtgttgatt
    13321 tccctgcacc actatgacct attattccaa aaatttctcc agattctatt tcaatactta
    13381 catctttaag cacttgaatc tttccataat acttattaac attttttatg ctaatcataa
    13441 aatttcctcc catatattct gctcagtttt tatgtttatc ctctcttatg tattacaaca
    13501 aaataaaagc ccgagtataa actcaggctt agaaagctat ttatactcat ctatcaacta
    13561 tattagttgc aggatttagc accaatgtat ataaaatata ctggttgccg ggtttcaaag
    13621 ggccagtccc tccaccactc ttgataagac gttatttaat ttaattctat tatcatttgt
    13681 tgctatgtta tatatgatat attcattaat agtatttgtc aataaattta tttaaatttt
    13741 ttatttttta ttatcgttaa ttaactattt ttaattagtt ttctagctcc taacacttta
    13801 tattttaatg tctatataac tatagaacat cattataaga aataaattaa ataacatcaa
    13861 tctatctaaa tcatctgtaa agtaaattaa gaaaattaac attttatcca aactctatcc
    13921 tactattaaa taaaataatt taaatacaat gatgattata tagctctagt actttagact
    13981 ttatcaaatg tttaagttct ataggttcta ttattgtagc atttttccca aaagttaaaa
    14041 aatattcagc cacccagtta agtgtagatt ttggtatata catatctatg tatccacctt
    14101 tagacaagat tttcaatcct cttgccaaca aaaattctgt ttcacaacat tttactccct
    14161 catctgtcaa attaatttta atatgataat ctgtacctac ttccatattc ttaagataat
    14221 catgtataga agataaaacc ttatatttct tacttgataa gttttctata ctcaaaatct
    14281 tcacaattct gtctacacga aattccttaa tagattctga ttttatacag taagctggac
    14341 aataccaaag tccattcatg gcatacaaac caataggaac aatggtacgt acactatttt
    14401 tttgctttga tgaatattca attttaattg tagattcatt cattactaca ttaaacaatt
    14461 ctttcaataa tggtgttgaa cagtgcctat ctggtgtcca aaaaacaaat ttacgcctta
    14521 tattctcaat attatattga atatcatttg gtatacaatt taaaaatttt tttaaaacag
    14581 aaatagtttc ttgctcaaat ggcaaatcat tataatattc tagtgactga tatgcaaaga
    14641 atatagattt tacctcactt tctgaaaatg caatcggtgg aagtatacgc tctttaagta
    14701 catgatatcc accagccgct ccaacttttg aatataatgg aaatccaata ctctccagca
    14761 cctgtaagtc tcttagtata gtacgttttg atacagaaaa ttcttctgct aattctcctg
    14821 ctgtaaaact tctttttgca tttattgtta tcatcagttc aattaaacgc tcagctcttg
    14881 acatatttat actcctaatt taaatatagt gacaataatt gtcactatta tatgataaga
    14941 tattcttaca tttaaagcaa taataatagt aaagaaagaa gggactgata ctttatggaa
    15001 aataatacta ttaaggctga tgatattatc aattattgtc tatcaaactt agatgatgtt
    15061 ttattaatga atagttgggg ggaacgagca atttactaca atcctaatgg tattttaaag
    15121 cgaggagtat atgttcttac cattaaagaa aaagacagta atcatgataa aggttcgttg
    15181 gttagtcgtc caaatgtata ccgtgtgaat ataggattaa aaaaagaaac ttttattgaa
    15241 atgtttggat atattccaaa gcgtccaggt gtaggtcaaa tagttgatat ggattttgat
    15301 tttacaaaat tggacacaat catgccacat cctatctact catggatggg atggatatgc
    15361 gtcctaagcc ctactgaaaa gacatttgag aactttaaaa ctttaatagg agaatcttac
    15421 aattttgcaa aacaaaaatt taaaaagaga aaaaacaagt aaaaacatat gaaaataatc
    15481 cctaaataaa ttataataaa aatattaagg ttacaagata aaaattaata tcttaataac
    15541 atgcaaaaaa gcgaagccaa aaaatgtatt atttataagg cttcgctata tctcaaataa
    15601 tttatttcaa atttcaaaac tatttattct attatttctt attatttcct gttattccta
    15661 atctatcatt catatctttt atcatttttc taaaaccact acctatatca tttccaacat
    15721 cttcagttcc atgaactaat tttataaagt cattttgacc ttttttcata tcttcatcag
    15781 ataccttatc taatttttct attctcttat ctatgtcttt tactaatctt tccccttcag
    15841 cgattaggtc atcattcatt ttctttaact ctgtatcttc tgttttacca tcttttttaa
    15901 gagatgttac aaatgattgt attttatctc tactatcttt atatgcagcc tttacatcac
    15961 ttagatattt ttcatttcct ggatattctt tatctttaaa ctgattattt atactttctg
    16021 gagtatcata aatagaatat ctatttagac ctgctatata atcattatag cttgttgaat
    16081 aataattcat atatccttca ttattattta cagattcatt aggatttttt cctgtatttt
    16141 cacttggttt ttcattattt ttagtacatg cagttatacc tatagctaat actagtgcta
    16201 atcctacaaa taaagttctt tttaatttca tttttattac cctcctagat gttttatact
    16261 ataaaaaatt ttaataattt tctttcttaa tttagtattt ctatattttt atattttatt
    16321 tactaaaatt aaacaagtta taatttattt ttttggaaat cataatgaat aaataattaa
    16381 ataaaaaaat tataatttta ttattgatat tgattatcat tcatagtata atctaattac
    16441 ttgatattaa ttttcatttg aaggaggtta tcttttatgt cttgttgtaa ttcacaattt
    16501 tgttgtaaaa ataaaattga atcatcatat ataaaatggc ttttagaagt tttaggtcca
    16561 gtctttttag gctctaaacc tgctgaaata ataaatattt cgtttactga tgtaaataga
    16621 gaggaaaaaa ttaatgatat ttataaatat ctatataaat gtaagaaaat agattttata
    16681 gttattgata aagaaaaaaa gggattaaaa atcttatttg taaataaaaa agcattatca
    16741 gaaaaattaa aatgtaaaaa aacagtaaac tttttaaagt ttttaggata caaacaaaat
    16801 acgaatgtta atgcttattt agagcattta gtagataaac ttaagagtga tgtttttcct
    16861 gatgaaatag gtattttttt aggatatcct cttaaagatg tgattggatt tatgggatat
    16921 agtaattatg aagtttctat gattaaatat tggaaagttt atggtgacac aaaacaatcc
    16981 gaggacacat attcgaagtt tttacttcac cgtaagaaaa tgagaaaatt actagactac
    17041 ataagtgtag ataaaatagt aagctgtttt taattgtatt tttgtataat aataaaaata
    17101 caccctcttt tatcatatag tttccataat aaataagggt gtattttcca ctttaatatt
    17161 ttaaagtatt ctaattttga ttgtacaaca tatctttaat atttattttc ttttgttgca
    17221 ttccattaga cattaaaaat tcctgtgtat cttctaattc ttttatatcc ttgtccgtta
    17281 ttttagaact aaagtcatac caagaataca tttcttttgt ttcatctaaa gataaaccaa
    17341 cttctttaga tacaacatcc atcacttcat ccttgttttc attcatatat tttaaagttt
    17401 cttcatgaac cttcataaat ctttttacta attcaggata tttttcagca aagtcatcac
    17461 ttacagcagt aactattatt ccacttacta atccttctcc atttacaatc attttggcac
    17521 ctgaatttat cgttttcaat gccactggac ctgcaagcat tgctacatca gcacttttac
    17581 tttctaatgc agaagcagca ctaggaatat ccatatttac atattcaaca tcatctatag
    17641 tatagccttc tttagcaagt gcagcaatca acagttgatg aagtatagtc ccttttggac
    17701 ctacaatttt tttacctttt aagtctttta tagatttaat attatcatta ttagttataa
    17761 gcatatatcc ttttggtgaa cggctataaa tattcgtaat tttaagacca acaccatttg
    17821 atgcagctat tattgcagac gttcctccta atgcatgtaa aaagtctagc tcacctgctg
    17881 ctaatgcttg agtttgctct ggtcctgttg tcaattcatg gaaattgact tttatattgt
    17941 cctttttaaa ttcctttcca aataaatcat cctttttttc taatatacta ggaacattaa
    18001 gtggtgattt tacataagtt aaatttattt ccttaggtaa actagcctct ttttttgcag
    18061 gttcatcttt cttatcattt gttgttgaac atcctacagt cccaaccaac accattatta
    18121 aagatgtcat tactgctaaa atctttttgt ttcttttaat caattaaaac tcccccaatt
    18181 cccttaatat ttcttttttc aagtttatat aatagttttt agttaaatct ctattatatt
    18241 catcttcgac actaaattgt ttaatccttt tatttttact aaaaacaatt attttctttg
    18301 ctatttccat agcttcttca atattgtgag ttacaaatac tacacctttt ttagtatttt
    18361 tatggatatt tacaacttct ttttgcattt ttcttcttgt gaagtaatct agtgctgcaa
    18421 atggttcgtc catcagcaaa atatcgggat tgaaggaaag tgctcttgct atacttactc
    18481 tgtgagccat tcctcctgat aattcatttg gatatgagtt tttaaacttt tcaagcttca
    18541 tcatttttaa atacttgtct aaatcaactt tatttctatt atctttttca gtatgtaaaa
    18601 gtatattttc acttacattc agccatggca taagtctact ttcttgaaat accattccta
    18661 cttttggagt acacttttta tcattattaa aaaaatatat gtttccacta gtagcatttt
    18721 caagccctgc taaaattcta agtagcgttg ttttcccaca tccactttca cctaatataa
    18781 cagttatctc ttcactagat atatttaaag atatattatc aagaactaaa tgctctttat
    18841 tatcaactaa atatttctta tatatattct ctagcaaaaa tccacttcta accatttaaa
    18901 tcaacctgct tccctttgct aaattttgtt attatctttg aaaatagata atctgaaagt
    18961 atacctaaaa atccaataac aaaaattcct accaatacaa catcagttct agacatatct
    19021 tttccatcag aaatcaaata tcctagtcct gaagaagctg caataagctc tgctccaatt
    19081 atagccctaa aactataccc aagccctaaa ctaagtccaa caacaatatc cagcatagaa
    19141 ttagggatta ttattttata aaaaattctc tttttagata aattaaaaga tttacctact
    19201 tctattaatt tattgtcaca attttttata cctttcaatg tatttaaaaa tattggaaaa
    19261 aaggatgcca aaataataat tataatttta gattcttcac ctataccaaa ccataaaata
    19321 agcattggca ccaaagctag tggaggtgta cttcgcataa attcaaatag tggtttgaaa
    19381 tattcataca tttttttatt tactccaaat aaaactccaa gtggtatagc catcaatgaa
    19441 cttattaaaa aacctattaa tatccttctt acactggcat aaacatttaa gaaaatagaa
    19501 ccgtcatata tcatttttat aaaagtatct aagactattt caggaggagg cagaatatag
    19561 ctactccata tacccaaaac acatactatc ttccataaaa ttaaaattat taaaaaaata
    19621 taatatcctt taagcctttt atgaattttc tcaaacatat aaaactcctt ttaacatatc
    19681 tatccctgct acccttttta ttttttaata tcttaaataa taattaagct atatcataag
    19741 atttaatcta tgccaagtct taatccacct gaactcattc tatcagaagg tgtagaatct
    19801 gtttttaagc cagacaatct ttcagatggt tgtataatga ctatttgtcc aggttcaaca
    19861 aattccatat gataagattc tcctgaagtc tgaccaataa aagtcttcca tgatagtttt
    19921 gatactttag gatatggttc tcttccagtc caagctacta atgcatctgg gtcaacacaa
    19981 caaggtcctt caagaattag aggattacca tctgttatta tagcaacatc ttgattttga
    20041 cctgttttat ttactaaatg tgtagtaaaa agaccttttt gagatattac ccctgaacca
    20101 atcaatttta cactgtaatt taattgttca gaaaatgcca ataagttttc actctcaaca
    20161 taaatggaat cacctgggtc aattgatatt acatctacat ggtaagcatt ttgagctagg
    20221 taaatttcac cttcaccttc aaccaccatt attggcattt gttctcctgt caatgacctc
    20281 tgaacatgac ctaataatgc tcttcccaat ccaccgccat tacttggacc taacagcaat
    20341 ttttcaaaat taaaatttcc tttaaaggct accatagcac ctttttttgc aaaaaattta
    20401 ccacttcccc ttgctataca cataagctcg tttgtaacat caaatttaaa cataatattc
    20461 acttatattg cttaatttag caataatccc tcctaatcat atatttatat ataattatac
    20521 agtaaaatta cagcatagtc taacctactt caaatatgaa atttgttatt tatacaaaaa
    20581 ataagaacct gataataaag caatttaact ttttatcagg ctcttatcct atttatctct
    20641 tagcgctatg acaactctta ctacttgagc atccagaaca accacatcca caactgctac
    20701 cattcttttt tgaattttta accatataca ttacagctag tgccattaat actactacaa
    20761 tagctgctat aataaatgta gccatattca tcactcctta tttatatgaa ttaatttttc
    20821 atataactta atttacccat tttttctttt ttcatatttt tatttgaata agttaaaact
    20881 acaaagacta ctgctactgc tataaatata gatattattg ccccagcaat acttcctcca
    20941 gtacctaaaa ctaaacttcc aacttgattt ataagaagag caattatata cgctgttaaa
    21001 gtttggaatc ctaatgtaat ccatgtccat ttccatgaac ccatttctct ttttatggct
    21061 ccaatagctg caaaacaagg tgcacaaagc atattaaatg ccataaatgc aaacgcacta
    21121 gctactgtaa acatgcttgc aactgaagca agaagtgttg ggtcttgctc tgttgcatct
    21181 gatataccaa ataaaactcc aaatgttcca actacatttt ccttagctac tagacctgta
    21241 actgttgcta ctgatgattg ccaatttcca aatccaagag gagcaaatat tggtgcaact
    21301 atatttccta agctagctaa tatactatct ccagcatcta ccatttgtaa tgaccaatta
    21361 aatgattgta agaaccagat tactccacaa gcaacaaata taattgttcc tgctttgatt
    21421 ataaatgctt ttcctctatc ccacatatgt attaaaacac cttttgcact tggaatatga
    21481 tattgaggta attccataac aaatggagat ggttctcctg caaataaact agttttcttt
    21541 aatataattc cacaaatgat tatcattgca atacctaaga aatacattga tggagctacc
    21601 catgaagcac ctccaaataa tgcccctgca aataatgcta ttattggaat cttagctcca
    21661 catggaatga atgtagttaa cataatagtc atttttctat ctctatcatt ctctatagta
    21721 cgagttgaca taactcctgg aactccacaa cctgaactta taagcattgg tataaatgat
    21781 tttcctgaaa gaccaaactt acggaaaatt ctatccatta taaaagctac acgtgacatg
    21841 tacccacaat cttctaatat tgataataat aagaataaaa gcatgatttg tggtacaaat
    21901 cctagtactg ctccaactcc accaattaga ccatcaacta caagtccttg taaccactct
    21961 gctacattta aagaagctag aaaattactt acattgcctt gaataatttc tccaaacagt
    22021 acatcatttg tccaatcagt tgctatagta cccaatgaac ttactgctat atagtaaact
    22081 ccccacatta taagtgcaaa aataggtaat gctagtatac gatttgttac aatcttatct
    22141 atcttatctg atacagtttc cttacctttt cgattcttct ttattatact tgaaattatt
    22201 gaactaataa attcataacg attggctgtt attatacttt cactatcatc atccaattca
    22261 tcttcacaat ttctagttat ttcttcaata ctattcaata ttgttttaga aatatcaagt
    22321 ttttgtataa cattttcatc tctctcaaat agctttatag ctaaccagcg tgtttctaca
    22381 tctatatatg gagtcttttc ttctattatt ttttcaattt tttctattgc atccttactt
    22441 tcatcaacaa agggtaattt gaaatttaat ttattgttac tacttgcaag ttcaactgcc
    22501 ttttcagcag cctccataat tccttgacct ttaactgctg ttacttctac cactgggcaa
    22561 cctataactt cagatagttc tttaatattt atcttatcac cattcttatt tacaatatcc
    22621 atcatattaa gagctataac ggtcggtata cctagctcta aaacttgagt tgtaagatat
    22681 aaatttctct ctatatttga tgcatctaca atatttatta ctgcatccgg cttatcatct
    22741 agcataaaat tacgtgtaac tacttcttct aatgtatatg gagataaaga ataaatacct
    22801 ggtaaatcta ctatttccac atctttattt ccttttaatt ttccaccttt tttttcaact
    22861 gttactcctg gccagttacc aacatattgt gatgagcctg taagcccatt gaacattgtt
    22921 gtcttaccac agttaggatt tcctatgaga cctattttta ttgacatttc cattccctcc
    22981 attattattt aaatacatca ctgtttgtga tatagaaaat cattctcatt atataattac
    23041 attaacccta ctctaattaa tctttattat tccacaataa ttttttctgc atctgactta
    23101 cgaattgata gttcataatc tctgactgtt acctcaattg ggtcaccaag aggagctact
    23161 tttcttataa atatattaac acctcttgta atccccatat ccattatacg tcttcgtgta
    23221 gctccttctc cttctaactt tttgactttt acagtctctc cacacttaat atccttcagt
    23281 ctgttcatgt cattacctcc ctatattatt attctacttg ccattttttt atctaatgca
    23341 actctagtat cttttacgtc tattattaag ttaccatcta tcttagaaac tattttaaca
    23401 tttgtaccca ctacaaaacc tatactattt aaaaaagtcc tcgtcttatc acttcccgaa
    23461 attttcttta taactacttc ttcacctgta tttgataata tcaatggcat catataatat
    23521 ccctcctctt aaagtaattt aaatctacaa gcaatcgtta tcttatatat aaattacaat
    23581 accttaaatc ttaatctatt aaaataatat cctatttttt ccttcttttt acaattccta
    23641 attttgattt aagtctatca caatagtata ttttttgcaa gtgattattg tattcttttg
    23701 attttttttc tcatttgatt tattttatta ataaaatcgt aaaaattaat acaaaaataa
    23761 agatgctcta aaatagtata ctcaactaat attaaagcac ctttattata tatgtcatta
    23821 tttacacatt gctttattct tttttaaaag cgattttttc aaactctttt acaggcattg
    23881 gcttagaaaa caaatatcct tgtaccatat cacacccaat ttgctttaga aattctactt
    23941 gcgaaatagt ctctacacct tctgatatta ctttcatttt cagttccttt gccattttaa
    24001 tgacattaga tataacaatt ttttcattat tactctcatc tttttctgta aaaaatgctc
    24061 tatctagttt taatatgtca acaggcaatt cttttaaaag attaagagag gaatatcctg
    24121 taccaaaatc gtccatagag attacaaatc ccttttcttt caaattgttc attgtatcaa
    24181 gtaatccttc tatattatct aatactgctg tttctgttag ctctaattct ataagtcttg
    24241 tcggaatttt gtatttatct acaattaatt taaactcctc tataaaatta ctatttacaa
    24301 aatgcattcg agacaagttt acagatatag gtactacttt ttgtccttca tccatccatt
    24361 ctctaatctt tttacacact tcctcaaata catagaaatc aatatttaca ataaaaccat
    24421 tcctctcaaa tacaggaata aattctattg gtggtattag acctttttgt ggattatccc
    24481 aacgaacaag agcctctgcc cctataattt gataatctga aaggctatat ttaggttgaa
    24541 aataaacaat aaattctcca ttattaagag catctaccat tgaattttca atttctttct
    24601 cttttaatat ttttttgtgc atttccttat cgtaaaaagc aaatgaattt ttatgaccac
    24661 cttttatagt ttttcttgca gtattagctc tatccataat agtatttatg tcattatcac
    24721 ttttacttat tttatatata ccacaatcta aaatcaattt ataatagttt attttaggat
    24781 tactaagtat ttgaacctta ttgtaaatat tgtttaacct tgttttaata tcatcatctg
    24841 tcttatactt aataagaaga acaaaatggt cagcagaaac tcttgcaaaa atttcatctt
    24901 cctttaattc acttgcaata gtatttgata tatgtatcaa agtatcattt cccatatcat
    24961 atccaaacat atcatttata tatttaaatt tgtcaacatc tatataaaac aacgcatatt
    25021 cttctggatt atttttagca aacagtttat tagaatttat tttaaattta tctatactat
    25081 ctgctcctgt caatgggtct gtatatgcta tcttccttag ataatcctct ttcttctttt
    25141 tattataaat tatatattta atagcaatta agaataaaat acatacaaaa gaaataattt
    25201 gtattgaata ttctttaaaa ataacaccaa atggtacttt ataaggtttg tcaatagtat
    25261 tagaatatat acaatcactt aattcttctt cagtaatttt gtctattgat ttatttaaaa
    25321 tagacactaa tatagggtca gttttatttg atacccctat acgcatccca tagcttgtat
    25381 ctaaaacaga tataacagat aaattctcac tctttccttc tcttaaaagt tcatcaaact
    25441 gataagaact aagtatcatt aagtttgctt taccttcatt tatagcattt agacaacttt
    25501 ctacactctt ataagatgtt gtcttagcat tttcaaaact cttttctata taagaatcaa
    25561 tagacttata actactagtt aaagcaatat ttaaatcatt attgagattg gtatccaatt
    25621 ttcctaccat aatcattgga atatttatgt atggatttgt caatttcata ttaaatcgtt
    25681 ttgccttatc attttcattg attgagccac atagcatagt tgccttacca ctttttatgt
    25741 aatcaagact ctcattataa ttttttgttt taatatattc aaattttata ccacattttt
    25801 ttgatataat tgacattaaa tcggaactta tacctttaaa tgaattgctt tctttatcat
    25861 aatactctac aggagaccac tctgaatcat ataccatagt aagttttggg tttgctttaa
    25921 taaaattcat ttcttgccga gtaaatgcta tggaattgtt gacctctctt ttgaaatatt
    25981 ttttatataa ttccaactca taatacatat catttatttt taattctttt aaagcataat
    26041 ctaattcttt taccaaatta ggtttatctt ttgcagtagc aaaataaaaa ggttctactg
    26101 aaaatttgct aactattttc attcctttag catttataat acttccacaa acaaatgcat
    26161 ctgccttttt ttcattgacg gactcaatta attcatcaat agaattacag tatatatatt
    26221 caactgaaaa attattttct tctctatact tctcaaatgc agtattatga aagtttcctc
    26281 taagtacagc tactctcatt cccttaaagg aacttatatc ttcataaaac atattattgt
    26341 tactatcctt tgtatatagt gcactatatt catatcctga acttagttta ggaaaattaa
    26401 atagtttatt tctttcatca ttcttctgta aaggtccgag taagtctatt tcaccctttt
    26461 ctagtctgtc taaacattct tcccaagacc cttttacaaa ttcatattcc catcttgtat
    26521 attttgagat ttctcttaga taatcataac catatcctgt ataagaatgc tcttttgatg
    26581 aggatattat tccatagtca tcacaatatc caactcttat tttttttgaa ttttcagact
    26641 catcagcaaa gcatagtata ttgttaaaac atgatataat aagtaaaaat atcaaagaaa
    26701 gtatcaagaa gtgcttttta aatgctttca tatttaaaaa cctccaattt gccaacttac
    26761 tttaacttat ttggttttct agttgtaact acttttattg taatggtaaa tatatcaaat
    26821 tgcaatattc tcatataata ttcttattca actataataa atttattatt atctatttaa
    26881 atacactatc taatattagt ttcttataag tcataaaagc acaactaaca ctataattct
    26941 agtgattaat tttatttcaa aaaatataat aacactacta atattttaaa tatcaatagt
    27001 gtcataaaaa cttttcagat taattaaatc tttctatata ttttataata atctaaatca
    27061 tgctaaacat ttagacagaa aacttttttc tttaatagta aatacttttg tttgaatatc
    27121 agaataatta tttgaatatc tatctataaa accatgattt gcatctaaaa tctcaatttg
    27181 gatattttgt ttcctagaaa gttggcaaga aatagaatca acatcaaatg aatcgtgctt
    27241 tgcaaatact aataaggtag gacattttgg aattacatcc atgtaatctc gaatccgaga
    27301 gccataacaa caaattatgc catcacaaaa agaatcttca ctgcatctcc atgcaatagt
    27361 cgctcccacg ctatacccag caacaaatac atatttatac tctgatttta aatcatttat
    27421 aagcttttca acttttttat aaatatcaaa accaacatta tttataaaaa aatcatatgc
    27481 ctcttggact tttgaatatg gaaaaactct tttttctccc agaagttcag gacaaaatac
    27541 atcatatcca tatttataat acttttgaca aacatcttct ataaagctat taatcccata
    27601 gatttcatgc aaaacaacaa tagctacatc acttttatgt atatacttta tcagattatc
    27661 caccaccttt acaaaacagc aaatttttta tacttagttt aatatattct tctttacatg
    27721 tcaatttact tttctaaaat caaatttatt tttggattaa tcatttattt ttaaaagttg
    27781 tgcattatta ctattaaatt attctctatt attaaaaata taatcgttag aaataaaaaa
    27841 taaagtacaa ataattaaaa aatatctcac tcataacttt aaaaattata agtgagatac
    27901 tcctaaaatc tactttatat taaatttatt ttccaaaata tctatttaat aatcctaaga
    27961 atgctttacc atgtctagct tcatctttac acatttcatg tactgtatca tgtatagcat
    28021 ctaatcctaa ttcttttgct ttcttagcta attttaattt tccatcagtt gcaccatact
    28081 cagcatcaac tctaactctt aagttttctt ttgtatctgc aactacaact tctccaagaa
    28141 gttctgcaaa tttagcagca tgttcagctt cttcaagagc tattctctta taagcttctc
    28201 ctacttctgg ataaccttct ctatcagctt gtctactcat tgctaaatac attcctactt
    28261 ctgtacactc accaacaaag ttagctctta atccttcgat tatttcttca tctacacctt
    28321 gagctactcc tattctgtgc tcatcagccc aatttttttc gcctttcatt tcttcaaatt
    28381 tatcagctcc aactttacat actggacatt gtgctggtgc agtatctcct tcatgtatat
    28441 atccacatac tgtacaaaca aatttcttca taattacttt cctcctaaat tttatatatc
    28501 aaattaaatt ttttatttat taagttagtc tatatatacc cgcaccatat acctttaaac
    28561 aattttttta aaagtttttt ctaaatacct attttccctg tgtcaataat atgtttctat
    28621 aataatgtcc ctttaatttt atcaattctt tatgatttcc tgattccaca attctaccat
    28681 tttctaaaac tattatatta tcacaatttg atatggtact taatctatga gctataatta
    28741 tacttgtctt tccataagtt aaattattta ttgcttcttg aattttagct tctgttgcta
    28801 tatctatgtt acttgtagcc tcatccaaaa taagtattgg agcatttttt aatactgctc
    28861 tagcaatact tattaattgt ttttgacctt cacttaaatc ttcaccccta tccgataata
    28921 tagtactata tccttcacgc attttaacta taaatttatg tgcatttgct attttactag
    28981 catatataac ttcttcatca gtagcctcca gatttccata ccttatattt tccataactg
    29041 tatcattgaa tatataacct tcttgtggaa ctactccaaa acaagttctc aaatagtttc
    29101 tgttaataga gtatatatcc ttaccatcta aaaatatact tccttcatct atatgataaa
    29161 aatttgtaat tagatttata atagttgttt ttccacttcc cgtctctcct atgatggcat
    29221 ttgatgtgcc agctttgatt tttaggttta tattatctaa aattttcttt tttgaatcat
    29281 aagaaaaact tacatcttta agctcaattt ctccctttac aaaatgagag tttaaattac
    29341 catctttatt atcgttaatc tcacttttaa acatgttatg cacttcttgc tcttcttgtt
    29401 catctataat ttcaaaaact ctttcacatc cagctatggc tgaaagtaat gtattaaata
    29461 gatttgctaa ttcatttaaa ggtcttgtaa attgtcttac ataacttaaa aaactagcta
    29521 taacccctat ggttataata tctttagatg caagaatgcc tcctataata catatagttg
    29581 caaatcctat attactaatc acattcataa taggcattaa aagagaagtg taaatttgcg
    29641 atttaaggga aatatttaga agtctatcat tgacttcttt aaaatcattt acagattttc
    29701 tttcataatt aaaagatttt actacattta tgtttgatac catttcttca atatgtgcat
    29761 ttagttttcc caactcaact tgttgttgct taaaaaagac tctagttctc tttgcaataa
    29821 aattactcac aaacattact atcggtatta atattacact gcaaaaggtt aaaattgggc
    29881 ttaatacaaa catcataata aaagtcatca atatgtttaa gattcctgta attaactgta
    29941 ctaatgaatt tgatattcct gtactgatat tatcaacatc atttgtcact ctactcataa
    30001 tatctccagt agaactttta tcaaaaaagg ttattggtag atttttaaat tttaaaaata
    30061 aattacttct catttctctg actatacttt gagataatct agctgtacat atccccttag
    30121 acagtttaac tgaaaactca attatataaa atgaaagtaa aataattatt ccttttaaga
    30181 aaatggattt tgaataagta ttgatatcta ttatgtcaac tacttttcca atagtatatg
    30241 gtattacagt tgatataatt gaatcaatta ttactagcaa aaaaataaat ctagtaatct
    30301 tcttatcttt tttaaagtac ataaaaattc ttttaaacgt ttttttaaaa tctttaggct
    30361 tttctttttt ctttaatcta ctgaccttct gatttccagt acttaaattc aatatacttc
    30421 ctccttaatt tacatcttca cttactaaat tctgcaacgc aaaaattttt ttataaattg
    30481 gagaactaac cagtaaatct tcatgtgtag caaatccaac cacctcaccc tcatccaaga
    30541 ctaaaatctt atcacagtca attatagaac taatcttttg tgaaatagtt attacagtac
    30601 atttcttact ttccttttct cttaaattac ttatatactc ttttatattc tttcttataa
    30661 ttgtctctgt attaatatcc attgcactaa aacaatcatc aagaattaat atttgtggtt
    30721 ttttggctat agctctagct atagtaattc tttgtctctg tcctcctgat aaatttttac
    30781 ccctttggaa taaaacttca tcataagtat tttcgagttt tgttataaat tgatttgcat
    30841 ttgctatttc acatgatttt acaacatcct ctttgcatat atctctattt cccataacta
    30901 cattctccaa tatacttttt ccaaacacac tactattttg aaatactaca cctattcttt
    30961 cccttaaact ttcttcagaa atactgtata tactacgtcc tccaatctta atatcacctt
    31021 tatcaattat atataatttt tgaattaaat ttactaaaga agtctttcct gaaccagttt
    31081 gaccaatcac accaatattt tgaccttctt ctattttaaa ggatacgttt tttaatattt
    31141 tttcatctgt atttttgtta tacgaaaaat ctacattttc aaaaattata tcacagttta
    31201 caaactttaa atctttttct ccaacgtcta aactttcttc tctctcaatt acttcttcat
    31261 tctcatcaac caaaacctca cttattctct cataagatgc ttttgcccta acaaaaacat
    31321 taaaaacatg tgaaatcatt ataagagatg ttaatattct agtcatatag tttacataag
    31381 caactataat cccaatttta atttctcctg aataaattaa atgccttcca attagtaata
    31441 ttattattat ggaaacatta atgattattg taattgtcgg tctaaaaaat gacatcatag
    31501 ttgtagcttt tctactattt ttaaaaagtt catcatttaa ctcttcaaag ctttggttct
    31561 cataatcgta tctacaaaat agtttaacta cttttattcc acttaaaaac tgtcttaatt
    31621 ttgaatttac tttatctgta ctttcttgta catttttaaa taatctatac cctatcttca
    31681 tattaagcaa tattataata aatataatta aaactgcaat tagaataatt attgacatct
    31741 ttaaatttaa ttttatagct ataattaaac ttcctataca cattattggt gactttataa
    31801 aaactctcat cattccatta acgaattgtt gcatttgatt gatatcatta gtaattcttg
    31861 ttattaatga agctctacca aatttatcta tttgttttaa tgagtatgta tttatctttt
    31921 caaatacatc ctgtcttaaa tcataagaaa aatgctgaga aactcttgcc gagattacac
    31981 ttcttattat tgcaaatatt gcacctaaaa aagttatacc tatcattata gctcctgttg
    32041 atagtatgta gtctaagttc ttatttgaaa cccctatatc tattattttt gccattatag
    32101 ttggttgagc taaatcacaa aaagcttcca atgttaaaaa aaatactgct gttagaaata
    32161 atactatata tttttttatg tattttttaa aatacctcat tcaatcatcc cttcatagaa
    32221 ttttctcatt accaaaagta tatcataatg gctaatttaa ttgattatat caattataaa
    32281 tatttgattt attattaatt tttataccat atattttata aattatttgt ttttatttcc
    32341 tatatttata tatatttata gcatactatt atatataata tatatgtatt aaaattaaga
    32401 caaaatttta actttactat ttgtgtaaaa agtaatataa tttaaaattg attataaatc
    32461 taactttttt ctttatcaaa atattttagg aggtgagaca tttgaaaaaa actaatagtt
    32521 taaaagaaat tttaaactgg aataatatca agaatttaag accttcaaag ggtttaaaaa
    32581 atatattaga aatttttaaa agtgacctaa aagatatacg tggcaattat gccgtacttg
    32641 taatagtttt aggtcttgct tttttaccat ctctgtatgc ttggttcaat ataaaggcat
    32701 cttgggaccc ttatggaagc actgctaata tgcttgtagc agtaacaaat gaagataaag
    32761 gaaatgaaat agcaggacaa aagattaatg taggagacca attaattgaa caactcaaag
    32821 ataacaagag tttaggttgg cagtttgtag atgaaaaaac tgctcttgaa ggtgttaaaa
    32881 aaggtactta ttatgcatca cttaagattc caaaaaattt tacaaaagat ttgacatctt
    32941 taattacaga tgatgttaaa aaaggcgaaa ttatctatac tgttaatgaa aaaataaatg
    33001 cagttgcacc aaagattaca gataaaggtg cttctacaat acaactacag gttaatcaga
    33061 ctatagtaaa aacagttagt gaaatcgttc ttggtatatc aaacggagtt ggtgcaggaa
    33121 ttgaacacag tcttccaaaa ttgacaaaag ttgaaaattc ccttattgac cttcaaaaga
    33181 gatttgacca tataaataag actgttgatt tagcttctga tgctacttca aaattatctg
    33241 atacagttaa agatattaaa tctgatttac ctacaattaa aaagactctg aatgatacaa
    33301 aactattatc aagtgactta aaaaaattct tagaggatac aaatgataat ttagacgaac
    33361 tttctcctct tattaagtct gacttaaatt taatggttga cctttcatct tctgcttctt
    33421 ctcttacatt aaatttaatt gatgcagtaa atagtggcag tgaagatgta cctaagttga
    33481 tagataattt atcagaaaaa ctttctaatt tgcaatcttt aaacgatact ttggtggact
    33541 ttttaactaa attaaaccaa cttacatcaa ataatagatt ggatgatgta atagataatc
    33601 ttgaagactc tagcaataaa atagattcat ctatatcaac attaaatgat attaaaaaca
    33661 aagttatatc tggacaacaa ccatctataa gtgctttgaa taatgtttta agtctatcaa
    33721 atggtattgg aagaattaat ttaaatattt taaataattt tgactcaaaa atatcaaaac
    33781 ctataaatag tatatttgca aacagtataa aagtagcaaa tgatataatt actgttttag
    33841 ataaggcaga agcaaaactt ccaaaggttg aagaaatact tactacttct ctaaaacttt
    33901 caggaaatgc acaggaaagt atatcattga taagagaaag acttccttta gcaaaaggaa
    33961 tgttggatga tttgattgat actttaagca aaattagtaa tggtgaagat atgaaaaaat
    34021 tagtcagctt gcttgaaagt gatatattga caaagtctaa tttcttaaaa gaacctgttg
    34081 aggtgaaaac agagaaatta tatccaattg aaaattatgg ttctgcaatg acaccatttt
    34141 atagtgttct ttctacatgg gttggtatat tacttatttc agcactattg tctacatctg
    34201 tacatggaaa ctataaacct tatgaaattt actttggaag aggccttact tttttaagta
    34261 tagctcttgt ccaaggtttt ataataggaa ctggagatat attattgtta ggagtaacag
    34321 caaaacatcc aattttattg atagttctgc ttatgtttac tagtatggta tttaacttta
    34381 tagtgtattc tttagtttct gtatttggaa atgtaggaaa agcaattgca atagtactat
    34441 tagtcgttca gattggttct tctggtggta cattccctat acaagttaca cctacattct
    34501 tccaaagaat aaaccctata atgccattta cctatgcaat aggtgctaca agggaagcag
    34561 ttggtggtat atatgctcca aatctaacta aagatatact agttctatta ctatttatga
    34621 ttctgtctat ttgtttaaat gtacttctaa aaggacctat aaatagagtt ataaaaccat
    34681 ttaatgataa atttggtgat agtaatttaa ctggtcatta aaaaattaat tctgtcttta
    34741 aatatatttt tttaataata ttctaagttc atattaaaag gtagtagcta aaaagctact
    34801 acctttttcc aacttaaaaa ctaatattta ctacaaaaac tgtcatagaa aaaaacgaaa
    34861 aaattcgttc tttcctaaat ttatcttata aatatttaga tatattccta cttaataagc
    34921 aaagctatac atagtattta atgtataact tacattattt aactcatata atcaattatt
    34981 cctgaattta aattatataa atgctcaaaa ccttcttcag ctaacaaatt acatgcagta
    35041 acacttctat gaccacttct gcaataaact actactttct tatctttata atcgtaaatt
    35101 tcatctatat tattgattaa ctcttgtaaa gatatattta tagcattttc tattttatat
    35161 tccttaaatt catctttagt tcttacatct aataataaaa catccttttc atttttcatc
    35221 atttctttaa gttgcttctt atttatattc ttatacatat gtctaaaatt cctccatttt
    35281 atttatatat tacctatacc ctttattctt tatacaacaa caaatattat ttttatattt
    35341 ttctctgtta tataaaaagc tatacttata aaagcttttt ttattgataa taatctgttg
    35401 attaaaataa ttaagaatgt tatgctaatt ataaattatt aaaaagggaa agaggtaatg
    35461 taatatgttt aagcaaaggc tctctaaatt attatctagt acattagtat tgagtatgtt
    35521 atttactgct gctccaaata ttacttttgc tgataataca aaagataatt ccgaaaaata
    35581 tcaaagttct gatatagaat tacatgatta tagtaaaaac gcggaatctt acacaaaaac
    35641 taaagctctt gctaaagaga aaatccaaac tttgctatca aagtatggtg ctgtaagtgc
    35701 tcaatatgct ttgattgata atggtaaaat tgagatttct ggtaatggtg gagtttacag
    35761 caaacaggat aacaaaaact taaataagga taatatgtat agtatcgcat ctatcagtaa
    35821 aatgtttact acaacagctg ttatgaagtt ggttgatgat ggaaaattaa atttagatac
    35881 tcctgttgta aagtatatac ctgaatttaa aatggctgat gatagataca aggaaatcac
    35941 tccaagaatg ttattaaatc attcatcagg gttgatggga agtagtttta aaaacactat
    36001 tttattagca gacaatgatt cttatggtca tgataatttc ttaaaagaat tacaaaaaca
    36061 aagattaaaa gctaaaccag gagctttttc tgtttattgt aatgatggat ttactttagc
    36121 tgaaatttta gtagaaagag tatctggtat gtcatttact aattttcttg ataaatacat
    36181 aaataatcca cttaacttac aaaatacaaa aactccagaa aatagttttg atagttcaaa
    36241 actagcaaaa gcatacgtgc cttattggga agatgcagtt ccgcaagata accttaatgc
    36301 tataggtgca ggtggtttat attcaagtgc agaaaatcta tgtacatttg cacaaacatt
    36361 tatgaaaaat tcaaatggta ttctttctcc tgcttcagta aaagctatgg aaaacaaaga
    36421 atatttaaat ggtctatggc ctgaaggaga agactctata cttggatatg gtttagggtg
    36481 ggattgtgtc aacacttatc catttaatca gtataattta aaagctctta caaaaggtgg
    36541 agactcttta ttattccaca gtaatcttat agttcttcca gatgaaaata tggcagttgc
    36601 agttctttct tctggtggaa gtagtcaact taacgaaata attggacaag aaatcttact
    36661 atctgcatta aaagaaaaag gtaaaattaa agaaataaaa cctgataaaa catttagtaa
    36721 gccacaacaa gttaaaatgc ctagctctct aaaagaaaat agtggtcttt atgcttcttc
    36781 aaatatgata aaagtagatg ttaatgataa tggtacttta acagtatctt ctccttatat
    36841 agaaaatgga ccagaagata aatatgtata cataggtcaa gatagatttg tatctgaaaa
    36901 aggtaacagc tgtctaaaat ttgtaaaaga aaaaaacaat atcacatatt taaatatgag
    36961 ctcttatgat gatgtccctg gattaggtca gacagcaagt ttatactatg tagctcaaaa
    37021 gatagatgac aacaatatat caaatagtgt aaaagaagca tggaaaaaaa gaaatggtaa
    37081 agattactat ctagtagatg aaaaatatac ttctcaaagc tatatgtttg gttctgtgaa
    37141 ggcaactctt gctctttctg atgaaactcc aggttatata gttaacacta aaataatgga
    37201 tgagaataac tcaaatgctt ttatagaaat acctggtgta ataggtcgtg atttatccga
    37261 cattaaactt cataaagaaa atggtacaga gtatttatct tttggaacac taacgtatgt
    37321 tagtgaagat tctataacta atttgccagc agaaaaatct tttacttgtg aactagaatc
    37381 caatggttat gcaaaatggt ataagattgg tgacgatctc gcaaataaaa aaatagaagt
    37441 taatcttcct caaaattcat cttttgctgt ttatgatgat aaaggtgttc ctgtaaacta
    37501 ttctttagtt acaaagaaca atagagttag attgccaaaa ggaggcgtaa ttgttttctt
    37561 aggaagtcca aatgctagat ttgaggttac atatcaagat gaagtaaatg caagtgcact
    37621 tacaggaact gatagatatg aaacttctat taagataagt caagcaggtt gggaaaatgc
    37681 tgaaaatgca gttttaataa acgattcagc aattgcagat gctttggccg caacaccatt
    37741 tgcatacaag aaaaacgctc ctatattatt gactggaagc tctcaaataa atgaaaaaac
    37801 tttggctgaa ttaaagagat taaaagttaa aaatgtatat gtagttggtg gagaagcttc
    37861 tataaatgaa aaatctttag atactataaa atcaaacaat atctctgtat ctagaatttc
    37921 aggaagtgat agatatcaaa cttctatgaa cattgctaaa gaattgaaca atattagcaa
    37981 tatatcaaag atttcagtag ttaatggcga aaaaggatta gccgatgcag taagcattgg
    38041 agctgtatca gctcaaaatg atatgcctat aatacttact aatgaaaata gtaatataac
    38101 tgaaataaat aacttattta aaaacaaaaa gattgataaa tcttatgtaa tcggtggaga
    38161 atatacagtt tctaaaaata tagaaagtaa acttcaaaat ccacagagaa tatcaggtag
    38221 cactagaaat gaaactaatg caaaagtaat aaaagaattt tacaaggatt ctaagataga
    38281 caatttatat gttgcaaaaa atggaatgaa taaacaagat gatttaatag acggattatc
    38341 tgttggagtt ttggctggaa aaactaaatc tcctgtaatg ctagtaggaa actcactaga
    38401 ttataatcaa aaagaactat ttaaaactat gagatttaaa tctgtaacac aaattggtgg
    38461 aaatggaaat gaaaactcat ttaagcaaat aaaagaaata gcttaacata actaaaaaag
    38521 gctgtattca agtaatatta attgaatata gccttttttt atttaagtta taagttttat
    38581 atgtgtaaaa attaaattta aatattaaat gataagttta ttaagatata gataagtcta
    38641 aaactttgcc ttttttaagt tagtttctat ttatcattca tacttaacaa tttatctaaa
    38701 tatactgact ttaattgttt attggctaaa atctttttag ctggttcaag ctttaatata
    38761 gctgacagta tagctcccat agctctatga ctagccagag cattattatc aaaaattaaa
    38821 ttttgtaact gccctttttc aattgccata agaactgctc tatgtactga atttgctgga
    38881 gttattattt tttcatctct ctttaataac ataatgctat ttttatggca atttctaaca
    38941 caaactccac aacctaaaca tctatcctca tcaattttta tatattcttt accatcttcc
    39001 ttaaccttgc ttatcgcatc tattggacat gcagttatac atttaccaca ctttacacaa
    39061 ttttcatggt ttatatttgg tataaaactt gttgtctgta ctggatgaag atttccaaat
    39121 cttttagctg ctaccattgc ttcacagcaa catccacagc aattacatat aaacgtaacc
    39181 cctttcctaa cattttctcc acattgaact aagttatgtt catatgcttg atgaagtagt
    39241 tctttacatt ctattttatc cacacgtctt gcaaatttat tatttattaa agaatttgct
    39301 acattgtcaa acgtcataca tatatccatg ggagcatcac aagcttttcc aacatgttgc
    39361 attctatgtc tacagtaaca catacttata cctatatgag ttgattcatc aattatatga
    39421 gtagcccttt catagtctaa aatactaacc tcattatcat tagttaaaac ttcctcttga
    39481 acgtatactc ttccaagctt cgtttctgtt gaataaaata aatctttgat aaaatcttct
    39541 tctacattca tatattgata gtaaagctct gccaaaagtt tttggtctat atcgtgtctc
    39601 gttctcatca tggcaaactc aaaaaaacca gccattggag gaggcattat atatttcttc
    39661 cctttattat cttctatatc tagtatcaga gccttactag caagtttatc caatactcta
    39721 tatgcttcac tttcacttac actccaaatt ttagctgctg tttttactct gaaaggcttt
    39781 attggaagct gagcaactaa cttcgcctct tgttctgtat atagtacatt tagtattttg
    39841 tataatgtat cagatggtgg agcaccttgt ggaaacttgt ttattctttc ctctaaactt
    39901 ttatacatat tcttcgcagt tatatgagaa atagtaatca ccttcttttt cttttgtttt
    39961 ccaataaaat caaatattct ttcttattat atattctctt actttatata ataccaattc
    40021 tttctaaata gttaaatacc tctagtaatt tattattaga tttcttatat aaataaaaaa
    40081 tcatttaagt gatataataa tattttatac cacttaaatg attttaataa tattttatat
    40141 agttaagaat tatttttata tctatatact ttctcttctt atattatcta ttatattttc
    40201 tttatttaat ttactcattg gtatataccc tgctataaaa gttattataa aaacacttac
    40261 tatacagata actatggctg tccacggtat aatcggagaa aattcaatta cacctgaaat
    40321 aagtttattc ataattagaa ttataccaat actaattggt attccaaaca acaatgacag
    40381 tataccatat ataaaacttt ctaaatatat cattttccta aatcctttag gagtaacccc
    40441 tatagattgt attactgcaa gttctctttt tcttagattt atacttgtac ttactgtatt
    40501 tagaatattt gtaacactca ctaaagatat cactactata aaaccatata caaatatttt
    40561 aataaccttt aaatcttgtt tttcactttc attgcttgca ctttcatcat aaaagttaaa
    40621 attattttta tttgccaaag cttctatttc cttcttagtc ttaatgcttc ctcctgaatc
    40681 aataaatata agacttttac ttaattttaa atttaaattt ttagcaactt catcataagt
    40741 tataaattgt aaccccatat tttgataacc aagacctaga cgttcttcat cagttatagc
    40801 aagaatcttg acctttactt ttttacttaa ggcattttca tcaagatatt cacaatttac
    40861 tgtatctcct actttatagt tggtaagttc tactacacct ttcttcccat tttcttcaaa
    40921 tgcacttttt ctaactaata taacaccatt ttcttcaatt gctctctctt tattaaaaga
    40981 gccctgtact aagttattta ttttgttttt tactgcaaaa tctcctggaa aaattaattc
    41041 attattactg aaatcatatt cataactatc tccaatctta tatttttgat aatatttcct
    41101 gattaaatct tccttggatt tatttatttt attttcactt actcttatag acacatattg
    41161 tcctgttgcc aattcaaagt tttttatccc atcaatatct tctagttcac ttatagtatc
    41221 ctctacagac ctagctgtgt tctttgcagt taaatacaaa tcatattttc tttgagaatt
    41281 tctaatttct tcacctctta gtaaaagtaa tgtaaagcca ctaaaagata taaatattat
    41341 tatacttacc attaaagaaa aaagagttat tataaatttt tttctatttc tcctaatatt
    41401 tttatatgca agtactcctt cagttttaaa aatcatttta ataagtcttg agcttttgat
    41461 tttgcccact ttatactctc cagtattttt aatcacatta aggggagaaa tattagaagc
    41521 cgatattgca ggtagtagaa ttgatataaa gattgtaaac aaaactatta ttatactaac
    41581 aataattatt attggattat acactatctg caaactcatc ttagtaacaa ccgattcagt
    41641 aaaatactta tttataattt taaacaataa gtctatagct actgttccag atattagtcc
    41701 tattggtata ccaattaaac taattataat accttctata aaaactaatc ttttaatttg
    41761 actagatgta gcacctatag aatttaatat cccaaactgt ttttttcgtt catttataga
    41821 aatactaaag gaattgtaca ctgtagcaat tgtacatatg attactaaaa tagttactgc
    41881 tataattata gactttatag agctatttat atttgaatac ttactagcac cttgtaacct
    41941 caataaatgt tcattgtatt ttatcatatc agaaactgct tctttatctt tatttgaata
    42001 tatattttta cttattttat tacttatctt atacacatct ttaggatttc ttactgctac
    42061 tgatacatta attgtatcat tgtaattatt cataggatta aagtaggcta tagctgttgc
    42121 aattccatta taacgttcaa acccaggttt ttcaattata ccaacaactt taaaagttct
    42181 atctttttca tttgctatat aatcaccttc atgaaatgtc atactatcaa tctttttctt
    42241 gcttgagtca aacatatccc ctacttttaa agttatctta tctcctattt ttaacttatc
    42301 atctataaga ttaataatac tttcacttaa aacaatttct ccttccttag ctggaaatct
    42361 accttctttt atagaaactt tatatccgtt tattgcattt ttatcatatt gctttatact
    42421 taatatagca ttttcactat tttctaattt agaatatcca agttgtttgg taaatgcatg
    42481 tttttctatt tcagctgatt tcgttacata ttccacattt cttctattta catcataaaa
    42541 tgtaacatgg aaacttccat cattctttat agtttctctc atttgataat ccataaaact
    42601 ttcaaatata tttcctatac cacaaattaa agctgttgaa agtattatac cgattatggt
    42661 tacaatggtt cttcttttat tttgttttaa gtatctaata gttagtgatg tatataaatt
    42721 catctacatc acctcatcac tttttatgat tccatcttct atgcttataa ttctatcagc
    42781 ttgaagtgcc atatttttgt catgagttat cattattagt gtctggttgt atttttttac
    42841 tgacaatttt aacaattcta atatttcctt tgaattttta ctatctaaat tacctgttgg
    42901 ctcatctgct aatattatag aaggtctatt aattaatgca cgtcctatag aggtcctctg
    42961 ttgttgacct cctgataatt ggtttggaag gtgcttttct ctatcaatta gacctaatgt
    43021 tttcattaaa tcatcaaaat attctctatc aatatctcta ttgtcaagct ctgctggaag
    43081 caatatattt tccttcacat ttaagactgg aattaagttg taaaattgat atataagacc
    43141 tatatttctt cttctaaata tcgccaaatc cttagttttt aaattataga tatcaacatc
    43201 atttatataa accttaccac tagttggtct gtcaactcct cctaataaat gtaataaggt
    43261 acttttacca cttccacttg gacctgttat tgctataaac gttccttttt caactgataa
    43321 acttacattt tttatagcat caacttttgt ttcattttta ccataacttt tagttatatt
    43381 ttctactctt aaaatttcca taactacctc caatatttat attctatact tcatatatta
    43441 ggttttggct attactataa agtgaattaa atattacaga ttagtcacta tcatacattt
    43501 tatgaaatat tatatgaaat tctgtaccct tacctttttc gctgtttaca tatatatcgc
    43561 cattttggct ttctattata gattttgaca ttgcaagacc tattcctaca ctatcttctt
    43621 ttgaactact tcttcctcta tagaatcgtt taaatacatg tggtatatct tttttatcta
    43681 taccttcacc ctcatctttt attattagtt cagaaaataa tggattttct ttataggtta
    43741 taattatatt tccaaattca ggagtatgtt ctacacaatt tttgattata ttcactaatg
    43801 cttccacgga ccaatcaata tcaccaatat aagatacatt atcatttccc tctataatca
    43861 gtttttgatt tttaatctcc ataggtattt tcatagatag cattgctcta tgtatgagtt
    43921 cactaaattt taccttatct tttttaaaat ttatcacttt tgcttctacc tttgataatt
    43981 taagcatgct tttaatcaac caatccattc tatttaattg atttt
//
LOCUS       DAFAZV010000032        43353 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFAZV010000032 DAFAZV010000000
VERSION     DAFAZV010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43353
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.032"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            340..1200
                     /locus_tag="KOU88_002475"
     CDS             340..1200
                     /locus_tag="KOU88_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK3212347.1"
                     /translation="MKKQKSPILLEMLGLFFGCISMSIGINMFLKPHTIAPGGLSGLS
                     LVLNKVTGLPVSAIMLIIGVPLVILAFRIMGTKNSLKTLFGTVVFSAIVQLTDPLSKL
                     RFTNDLLLSSIAGGILVGIGLGIMFKSDASTGGTDLIALILSKKFPGIKATKFMSCLD
                     GMVVISSGIVNRSLETALYSGIALCVLIKIADMIMEGFDHSKAFFIISDEPESLRQAI
                     TEELDRGLTILDGKGGYTRENKEVLLVVVSKKQELYLKRLVKRTDPTAFVIVTDVHEV
                     LGEGFKNLEN"
     gene            complement(1439..1996)
                     /locus_tag="KOU88_002476"
     CDS             complement(1439..1996)
                     /locus_tag="KOU88_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3212348.1"
                     /translation="MSDSEYPQMKTLETRNCILRPASLDDVEDFFDCYKNKIVVKHLP
                     FSEHKSLEDTRKFIKSFFLNPYKKGKIGHFAIVYKRDNKVIGNMGFNNINPKALEAEI
                     GICINPSYWGHDFATEITKRVIQYGFRELNLNKIIAITYEENQNSTKSLDLLGFKCTG
                     KYIKKIHTGNTVKNVPCYQYELKKQ"
     gene            complement(2186..3073)
                     /locus_tag="KOU88_002477"
     CDS             complement(2186..3073)
                     /locus_tag="KOU88_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3212349.1"
                     /translation="MNIKLELYKVFNAVVNNKSFSLAAKELFMSQPAVSQSIKQLEEQ
                     LDTLLFYRNNKGVKLTPEGKILSEHVTTALKLISSGEDRINKFKKLEYGSLKIGVGDT
                     AARFFLLKYLEIFHKKYPHIHVSTINRTSRELISLLKDGNIDIAIINMPIEDDTLNIV
                     ECIEIHDIFVCANDYIEYKGRKISLEELNTLPLIMLENKANSRLYVNEYFLSKGIKLN
                     PDIELGSHELLLEFAYINLGVSCVIEEFSIDYLENEKLFKLDIKEPIPKRNIGYCHLK
                     DISLSLATKEFLSMISNNI"
     gene            3192..4391
                     /locus_tag="KOU88_002478"
     CDS             3192..4391
                     /locus_tag="KOU88_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003493023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coenzyme F420-0:L-glutamate ligase"
                     /protein_id="HBK3212350.1"
                     /translation="MDRLVGTVSRGVRAPIIRQGDDLVKIVVDSVLNASKSENFEVRD
                     KDVIAVTEAVVARAQGNYAHVDNIAKDVKDKFGDDTVGVIFPILSRNRFAICLKGIAK
                     GCRKVVLMLSYPSDEVGNHLISIDELDDKGINPWSDVLTEEKYRELFGYNKHTFTGVD
                     YVDYYKNLIKDCGAEVEIVFANNPKTILNYTTSILTCDIHTRQRTKRILRQNGAKKVY
                     SLDDIMTASVDGSGYNDQYGLLGSNKATEETVKLFPINCDEVVNKIQGNIKEITGKDV
                     EVMVYGDGAFKDPVGKIWELADPVVSPAYTKGLEGTPNEVKLKYLADNDFADLSGDEL
                     KEAISKYIVEKDNKSDDLTGNMVSQGTTPRRLTDLIGSLADLTSGSGDKGTPIIYIQG
                     YFDNYTK"
     gene            complement(4585..7140)
                     /locus_tag="KOU88_002479"
     CDS             complement(4585..7140)
                     /locus_tag="KOU88_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBK3212351.1"
                     /translation="MMSLVKFSIQYIKHYKKQSISIVLSIVLSVALLTGIGSLVHSAD
                     KSRIEKIREDSGDYHYFYKVDKEQLNKIKENKKSKEYTVDRLGVTKPKNQIDEPFIIE
                     FLNADSSYLDMTGRKLLKGTLPSKDGEIVLDTYSLNNLNVNKEIGTEINLDGKIYKLC
                     GILSSLSNPETALEGFVNDYFQPKEKDSYIVYVKYDENKNIKKQNYKFMKKFNISKEK
                     TYINWSLSVEFGVKPPKNIEKYNIFEFLKNLELNTNAIILLVGVFGAAAVYSIFHVSI
                     LQRISQYGVLEVLGANNKQLLFLLFLELFLLFIVGFPIGCFLGIGVASTIYEQFPHIF
                     LSSDIVPGAFFISEKSIYLGFLFILLLLILIAVRVVHQLNKYSSIESMKNFKITNKKK
                     RILESVKHSNMTKVLSHKYMTQKKGMFIGILFSLSLGGIIFLCSSYSIQLTKNNNELT
                     MKADDGLNSDYQITMQTTDFDVGIPKDKISRLNNVEGISKVYPVRYLFGAMQIKEEQL
                     FWKNFFKPLEKDYRIKTFFDGICTKQNEGGYLLKTNIYGYNNGMLEGLNSYIIDGEIN
                     THDMVKNNKVIVRLPMDGTGMYDAVDINPGDTIKVKVPKTMKPTDEIVKFKEENKNDY
                     TTKEFVVAATVKRVMANNIYFIGDYGMDIVMTNGQMKNNFDIENYNSVSIKKTEDSNS
                     EELSENIKSVVSDVKRCIVTDYTIAIEKNNTYLNQKLLFIYGIVFVLLAISLFHIINT
                     VSYLIFSRRHEFGILRAMGITDNKFLLMMIREGFLYGFYASIIMVIGSVIGQFMIYFM
                     VKRVYLYINPILKINTPLYIGMIILNITISIVAVIIPVRQILKSDIISEINKN"
     gene            complement(7137..7823)
                     /locus_tag="KOU88_002480"
     CDS             complement(7137..7823)
                     /locus_tag="KOU88_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212352.1"
                     /translation="MSILVTNNLVKHYGKGETKVKALNGVSIEIERDTFTAIVGTSGS
                     GKSTLLNIIGGLDNPTSGDVIIKGKNISKIGKKDLTVFRRRNIGFIFQNYSLMPVLNT
                     YDNIALPVTLDKGNHIDHEYIEMLMKTLGIWDKRLKFPSELSGGQQQRVAIARALANK
                     PALILADEPTGNLDSKTTMEVVCLLKESSAKFHQTILMVTHNENIAQVCDSIIHIEDG
                     VVVNTGGELL"
     gene            complement(7900..8808)
                     /locus_tag="KOU88_002481"
     CDS             complement(7900..8808)
                     /locus_tag="KOU88_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3212353.1"
                     /translation="MFILAFIICTVVIFIVSTKINRKRYDELNLMLNQILEGKEVTYP
                     DTKDTRASKISHQVKKIKDMIEIEVEQSKSEKEAIKGLISNMSHQLKTPLSNITIYCE
                     LLENINISTLQKKEFLQKMKNETFKIDWLLQSLFKMTKLEDGVIEFEVEELLIKDTLI
                     QSISTIFNKAEAKNIRINLEPFSDIKLVHNKKWTIEAIVNVLENAIKYSPSDSTITIS
                     VIKMELYTKITIKDEGIGIDSRELNDIFKRFYRSKNVENQNGTGIGLYLTRLILEKEN
                     GNIIVESKLGSGCCFSIFLQNCKSLN"
     gene            complement(8810..9481)
                     /locus_tag="KOU88_002482"
     CDS             complement(8810..9481)
                     /locus_tag="KOU88_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3212354.1"
                     /translation="MNLLIIEDDINLNEGLFYAFENDGFNVFKAYTKQEGLNIFNSKN
                     IDFIILDCNLPDGDGFDVCQIIREKSDIPIIMLTARDSEIDEVKGLEIGLDDYITKPF
                     SLSVLKARVKVAIRKKSNNKVIYSNGIKLDQKLLKVYKNKECLELSSVEYKLLSYLIE
                     NKGQILLKEQILHHIWDSEENYVDDNIVSVNIRRLRVKVEDDPSNPKYIKTAYGMGYL
                     WNEVE"
     gene            9743..10807
                     /locus_tag="KOU88_002483"
     CDS             9743..10807
                     /locus_tag="KOU88_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S ferredoxin"
                     /protein_id="HBK3212355.1"
                     /translation="MKRVDERNTMFARANYKKDSTAYNDYYKKNPDKKEIDDSIRNRP
                     NLCSEGTMTYNELNSPMASSAFDFLSDIKSLCEGKVSDTKVDVDAKSMTKKIKGLAKQ
                     YGASVVGITKLKDYHIYTNRGRHEENYGEEINLTHKYAIVFGCEMDKEMINRAPMICE
                     VIETSKCYVDASIVGMILSYYIRNLGYDARNHMDANYLVMPVFIARDAGLGDIGRNAI
                     LTNKDYGSRLRLGVVTTDIPLLEDEYVDFGLEDFCKVCKKCSFNCPSHSLSNDIKIGD
                     DGKYNWVIEHETCYIKWRYLGTDCGMCISACPFSQNLETIKNTTSFKGNNELIQKALD
                     EYTSKFGKRIFIPGNPSWLK"
     gene            10965..11651
                     /locus_tag="KOU88_002484"
     CDS             10965..11651
                     /locus_tag="KOU88_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3212356.1"
                     /translation="MEKILVVEDDSILNKTLSYNLIEDGYIITSKFTAKSALKSIFEC
                     EFDLIILDINLPDKSGFELCNEIKENYNIPIIFLTANDMECDMIKGYELGALDYITKP
                     FNINIFKQKIKAFLNHLTIKTKQDYYRDGYLEINFSELSANINGNQIIFTPLEYRTLK
                     LLTENPKSILTRKVLLEKLWDIDANFVDEHTLTSVISRIRSKIEKDNLKYIKTVYGMG
                     YMWLGERNEF"
     gene            11641..12672
                     /locus_tag="KOU88_002485"
     CDS             11641..12672
                     /locus_tag="KOU88_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3212357.1"
                     /translation="MNFKKFSFSSIYLIIAVGIIFTAILFSISIYLITDDLKLIALLL
                     IYTIVLCGFIALIIFLLHKKIVIFCSKICHTLDSMMNSEDNIEIELEEETILSRINHR
                     LIRMYEVIQENRNSIAIEKADLQELVSDISHQIKTPIANLKMINTTLLNQTFKTEIQK
                     DFLMDMENQLDKLDFLMQSMVKTSRLETGIITLSKKKNSIYETIATALSGILFDAEKK
                     NIEVTVDCDPNLYIIHDKKWTSEAIFNILDNAVKYTSSNGKIRVATECWVMYTKIDII
                     DNGKGISESRQAEIFKRFYREEDVHDIEGIGIGLYLSRKIISLQGGYIKVTSDIGKGS
                     TFSIFLPNK"
     gene            12754..13419
                     /locus_tag="KOU88_002486"
     CDS             12754..13419
                     /locus_tag="KOU88_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212358.1"
                     /translation="MSILQVINLKKYYGQSSNITKALDGVTLSIEKGEFISIVGTSGS
                     GKSTLLNMMGGLDNPTSGKVIIKGKELSTMTDEQLTIFRRRNIGFIFQNYNLVPLLNV
                     YENIILPIGLDGETIDKDFINEIINMLSLEEKLYDMPSNLSGGQQQRVAIARALVTKP
                     AIILADEPTGNLDSRTSSDVLSLLKVTSKKFNQTIVMITHNNEIAQLTDRIIRIEDGK
                     IVN"
     gene            13432..15849
                     /locus_tag="KOU88_002487"
     CDS             13432..15849
                     /locus_tag="KOU88_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212359.1"
                     /translation="MFRNNNRTFIRKIALNDLKINKLKTYLSGIIIMISTCLLLTVTL
                     VSYNASVDLVNASPYHAIYKSVDEKAKNILYKDKNFSGVGTYKLIGSNKKTDCIMSIV
                     YADDTAIKLMNFQPLKGKLPTNKNEIAISEKYLQEFGLDKDIGDSIKLNYYDDITNKE
                     VQCDFIIVGFLENYYQDNAKQYYTVVSNDYFKNIASTPLQNKSNTFDESRPDTVDVLV
                     KLSEENTEKDSASIKTQLKKIGLSLGIKKYNIYLNDNYIESNLIDGEQIITVLVVGIV
                     VLFSSVFVIYSIFYISVVNSVQMYAKLKSLGMTSFQLEKIISLQGNILSIIFIPLGVI
                     ASCIIAYIIQPLAWQMIADLFIILILSLVMFLTVRISLFKPARIISKISAIEAMQYTE
                     TKFRKKAKNFSYINIKNLALKNIESNRKKNLIALISLSISGVLFISIANLANSIDFKK
                     QLSQQFVYNEDYIISIKSDNLYEHITEIQQNNPLTDSLKNEIKSIHGVKKLIESKSIK
                     SNIIEPYIKDRDEKQFITLIKGITPELSKSLEEYIVSGKIDYTHLDSDSLIINKYRTK
                     YYGLNLKVGDTVTFNIFSGNDIIKKKMKIIGIIDNSNTGGMFFASDKTLESLTPYNTN
                     LDFSILIDKKHSKEVEEKLLSIIQKNSNLMLYSYEDDYRMITRAFQYIIIASYIFVGL
                     ISCFGILNMTNTLINSVLIRKKEFALLQAVGMTRKQLRNMLYREGLNISIKAICTSSI
                     LGYFGSNLLCTFIKDVIRLDFINFKFSIFTILIFSFVLIGIQVLVTELLVRNIEKKSL
                     TERLRSQ"
     gene            complement(16030..16821)
                     /locus_tag="KOU88_002488"
     CDS             complement(16030..16821)
                     /locus_tag="KOU88_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK3212360.1"
                     /translation="METKQYLIDFYNTYDEDSRLALKHGMVEFLTTMHYIDKYIKSGD
                     CVLEIGAATGRYSHTLARQGYDVDAVELVEHNIEVFHKNTQSNENISITQGNAMDLSV
                     FPDNKYDITLLLGPLYHLYNKEDKQQALHEAIRVTKPGGVVFAAYVISDGCLIDEGFH
                     RGNINVSEYIEKGLIDPQTFAAKSEPKDLFELVRKENIDDLMSAFNVTRLHYVASDGL
                     ALYMREAVDSMDDDAFALYLKYHLATCEREDLVGVTSHAIDIFRK"
     gene            complement(16854..17441)
                     /locus_tag="KOU88_002489"
     CDS             complement(16854..17441)
                     /locus_tag="KOU88_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3212361.1"
                     /translation="MPPKVKITKEMILNTVLDITREVGFEAVNARSIASKLQCSTRPI
                     FTCYENMNELKNEFLAFAYEYYNQYVVNYRNSKSVSPYLLLPLSYIEFAQEETYLFKL
                     LFINDLDLMMKEANDFYKEIDNEKKARLFSESIGIELECAKVIFLDLFLYTHGIAVLT
                     ATKKLTLDRYSAEKMLKNILTAFIRQEKPDWNLSI"
     gene            complement(17618..19009)
                     /locus_tag="KOU88_002490"
     CDS             complement(17618..19009)
                     /locus_tag="KOU88_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBK3212362.1"
                     /translation="MERLARREQPHIKFGMFKIRIPFIHYRFEKPEAIQGIISSMTSL
                     GTIGLSTQILGLPYEVAWSMAIINSILYCLHVFMGDPVVPGWITASITLTTAYLLKFS
                     MGIERIQALTALQIDLGIIFILMGITGVAGKLVSKIPNSIKGGILMGVGISTIISEFN
                     PKGRFDSYPISITVGILVACFVMFSERFDTLKVKNKFLFHLGEYGVVSAILVSLIVGI
                     FSREIEIPRFSFDNLVYIVDFKNLINTVSPFGIGFPSVMLFIQGIPMAFMIYIIAFGD
                     FITGENLVLSESENRKDEYIDFNSNRSNVISGIRNIFMAIFSPYIPMCGPLAATLTGS
                     VAQRYKVGKEAMQSVFSGMGTLVWVSAIFICFYPIAQIATPLIPLALSVTLLVQGYLC
                     TKLSMELCNTGVEKGLIGLMGGVIAAKGGTWGLAVGFILYFILIDSKKRKEKDINSIE
                     DCVYEILDKKKSI"
     gene            complement(19199..20497)
                     /locus_tag="KOU88_002491"
     CDS             complement(19199..20497)
                     /locus_tag="KOU88_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase/BAAT N-terminal
                     domain-containing protein"
                     /protein_id="HBK3212363.1"
                     /translation="MKVNVYNVESFVDERLKIMVSDLIPNTKLKISVKMEFPWCKGEE
                     FSSYGVFCSNEKGEVDLDLVEPIEGTYKADNCMGLIYSLEKSKTEGKNFAENISIDKP
                     IIVNMIFETSIERKEVELKRIFKSEDITTKYISDEFIGKLFYKQNSNNKTILMLGGSD
                     GNLDALDLLAAPLASRGFNVLTVAYFALEGLPDKLEEVPLEYFEKVFEWISENEITST
                     KEIFVHGTSKGGELAFLLASRYEQIKKVVVSQPHIYCFQALNGLMSGNDTSSWSYKGE
                     PFPYIKVDNDIFFEEQKKNISKGIPFGFNSTYKKSLKRAENRKEARIKIENSKADILM
                     IAGKEDNIWNSYEACLETLEIFEENNYPYNVELLTYNNMGHPLPIPYIMPLKETLCMS
                     MSGGIFSSGGTVEGNSKGQFESWNRTIEFYKKPLSSDLNN"
     gene            complement(20857..21732)
                     /locus_tag="KOU88_002492"
     CDS             complement(20857..21732)
                     /locus_tag="KOU88_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBK3212364.1"
                     /translation="MITFDVNGAIIRFDDTKNNYNKIRKIFKLYALEISKNFERDCLN
                     SFQNLKQISDRGLSLGEKYIEESFKKGIETIVSFGIITIDIDTFKSVYCEKYLDFKRL
                     FNNLNKTFIIPNKNKKNGHASFLEIESTIKKMSNYLYNDCFKIHYAVVDALIENRITA
                     VHSYIDEESIKKSNALFNNYKDGFIGKADECKVVKQIITLNPYREDVYEFLVKEDGDF
                     SKEIERLTEFLGYDIREYKASLMDIYINELMESDENDVENAKEKIEKYARYIGCSDEN
                     LYVARVNAIYTFANA"
     gene            complement(21925..22611)
                     /locus_tag="KOU88_002493"
     CDS             complement(21925..22611)
                     /locus_tag="KOU88_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBK3212365.1"
                     /translation="MFGVIANSLAIAGGCIVGLIIKGGLPQRVSDTIMNGIALCVLYI
                     GISGALEGKNTLVTIISVAVGALIGELIDIDKWVNKLGAFLQSKFSKGNKKDSIAEGF
                     ISSSLLFCIGAMAVVGSLESGLTGSHDTLFVKSVIDGIASIIFTASLGIGVMFSAISV
                     FLYEGIICVGASFLNGFLSDPVVTEMTAAGSLLIIGLGLNVLKLTNIKVANLLPAIFI
                     PILFGVFGII"
     gene            complement(22660..23193)
                     /locus_tag="KOU88_002494"
     CDS             complement(22660..23193)
                     /locus_tag="KOU88_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBK3212366.1"
                     /translation="MSDLNNKKEQDENESSMNETKIYDILDKLNVEYDVVEHEAVYTA
                     EQLVILDGITKGCQCKNLFLRNAKGNKYYLIVVKGEKQVDLNSLKDKIGSSRLSFASP
                     ERLYNVLKLLPGSVNPFSLINDTERKVELYIDKDVIKEDYLNFHPNINTKTVNISRKG
                     FEEFLEYLKYPIQSIDV"
     gene            complement(23237..23869)
                     /locus_tag="KOU88_002495"
     CDS             complement(23237..23869)
                     /locus_tag="KOU88_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBK3212367.1"
                     /translation="MKVFDLTHVTHNDMPVYAEPNRPDIKKVAIIEENGYQETLISVF
                     SHNGTHMDSPRHMYTKGETLDKLDIENFVGKAYVLELEKGNENIELEYLKKYEDEIKN
                     SDFIIFKSGWSKFWDKKQYYVGYPTLTKEAANYIANTNIKGIGIDMLSVDRYDTSVFE
                     VHHILFEKGKIIIENLTNLENVPEKFLFIAAPFKYNDADGAPVRAIAIVE"
     gene            complement(23959..25038)
                     /locus_tag="KOU88_002496"
     CDS             complement(23959..25038)
                     /locus_tag="KOU88_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HBK3212368.1"
                     /translation="MKIAIFLGAGASAAENLPIQNELFSEYFKKLNPTNYNTKMNREL
                     YIFFKQMFNIDIVKDNIDNANFPTFEEVLGLLDLAEQRKEAFRNFGLENLNNRSDSIR
                     FLRQYLILLMAEAIHNTPRTDNKYHKLLVENLLENDLLLDTTFISANYDIHIDNTVTG
                     LRDKNDLPIMLDYGVEFTNFKEELNWRKPKEPLIKLYKIHGSLNWLYCPICNSVTLTP
                     HEGGVMKLIENSSETKCLECGELTEPIIVPPTYFKNMSNIFLSNVWNETEKTLRDTDL
                     LIFCGYSFPEADMHIKYMLKRVQTNRKKPPLKIMVFNNHSQKQRITLKKEEGRYKRFL
                     GEDVIFTDNSFQDFSVNPLRFIKNI"
     gene            complement(25171..26517)
                     /gene="pepV"
                     /locus_tag="KOU88_002497"
     CDS             complement(25171..26517)
                     /gene="pepV"
                     /locus_tag="KOU88_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBK3212369.1"
                     /translation="MKEQIKEKVNSLQDEMISSIQESVKIPSVISEATENCPFGENVD
                     KALRGILDLCKSLGFKTVYKDGYYGYAEIGQGEKMIGILGHVDVVPEGDLESWNYPPF
                     EAVLEDGKLYGRGTQDDKGPTISAIYAVKALMDLNVDFNKRIRFIFGADEENLWRCIN
                     KYKENNEEIPNYGFTPDSRFPITNAEKGLLQVHLTCDSKSDIELSVGKALNAVPGKAI
                     YIGKYSDKLKKELNKLNFEYTVEGNKICIIGKSVHSAASDTGINAVARLCIALNNIGI
                     DSNIIKFLAEVIGEDANGNNIIPNCKDDVSGKLTVNIGRVTIDNEKEFAGIDVRIPVT
                     YKKDDFVKELKKMTDKYNLNYEEYDFLDSIYVPEDTLLVKTLRKVYEEETGLDGTPLS
                     SGGATYARALDNCVAFGAIFPGKPETEHQANEYLIVEDIIKATQIYALSIYELLKI"
     gene            complement(26586..27866)
                     /locus_tag="KOU88_002498"
     CDS             complement(26586..27866)
                     /locus_tag="KOU88_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine gamma-lyase family protein"
                     /protein_id="HBK3212370.1"
                     /translation="MLNETKELLKDYYGIDDDTFKLSQEIMEEIKDKFEEIKEIREYN
                     QYKVLKAMQESKLSDMHFNWTTGYGYNDIGREKIEEIYSKVFNTEDALVRPIIVNGTH
                     ALTLCIQGIVRPGDEILSVTGRPYDTLEGVIGIREEKGSLKEYGVTYDDVDFLEDGNL
                     DLEGIKNKINDRTKLVMIQRSKGYSWRKSLSISDIKEAIEVIKSVKPEAIVMVDNCYG
                     EFLDTKEPTDVGADVMAGSLIKNPGGGLALTGGYIAGRKDLIELISYRMTSPGIGKEC
                     GLTFGTTRNVLQGFFLAPYIVSQAVMGAIFCSRAFEKLGYDVLPKYDDLRSDIIQCIR
                     LNNADEVISFCEGIQEAAPVDSYVKPVPWDMPGYESEVIMAAGAFIQGSSIELSADAP
                     IRPPYNVYFQGGLTFDHSKMGTLKAIEFIKKLKK"
     gene            complement(27993..28253)
                     /gene="hfq"
                     /locus_tag="KOU88_002499"
     CDS             complement(27993..28253)
                     /gene="hfq"
                     /locus_tag="KOU88_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBK3212371.1"
                     /translation="MKNTVLNLQDLFLNNARKERIPVTIYLVNGVQVKGLVKGFDSYI
                     ILIEGDNRQQNMIYKHAVSTIQPGKYINLTNQNQNNNNNNNR"
     gene            complement(28367..29302)
                     /gene="miaA"
                     /locus_tag="KOU88_002500"
     CDS             complement(28367..29302)
                     /gene="miaA"
                     /locus_tag="KOU88_002500"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBK3212372.1"
                     /translation="MKKIPLIILTGPTAVGKTDLSIKLAKDMNAEIISADSMQIYEYM
                     DIGSAKVTEEEMQGVKHYLIDEVKPDYPFSVSEFQQRAKKYIHEINKKEKCVLVTGGT
                     GLYLNSLIYNMDFAQSDANNELREELQKQLAEKGIDYMHNKLKELDEESANRIHKNNT
                     KRVIRALEVCLSGKKMNDFSSDLKFNEEYQPIIIVLNRDREHLYQRINMRVDIMLKNG
                     LVEEVKKLLSMGFKKDMISMQGIGYKEILKYLDGEYTYEEAIEIIKRDSRRYAKRQIT
                     WFKRYKTAKWFDLDQYENIDELKNEIILYIKDSIK"
     gene            complement(29340..31307)
                     /gene="mutL"
                     /locus_tag="KOU88_002501"
     CDS             complement(29340..31307)
                     /gene="mutL"
                     /locus_tag="KOU88_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBK3212373.1"
                     /translation="MKNIINILDDLTINKIAAGEVVERPSSVVKELIENSIDAGANKI
                     SIDIIDGGKSLIKITDNGIGIPSSEVEKSFLRHATSKIKKIDDLYDLYSLGFRGEALA
                     SISAVSKLEMTTKTKDEIIGTKIYVEGGKIISKEPIGSTNGTTIIIKDIFFNTPARQK
                     FLKSTHAETINISDLINKLAIGNPNIQFKYTNNNKQMLNTPGDGKLVNTIRSIYGKEI
                     TENIIDVEFKCNHFKMNGYIGNNNIYRSNKNLQHIYINKRFVKSKIIIDAITESYKSI
                     IPIGKHAVCFLNIEVDPSCIDVNIHPNKLEIKFEKEQEVYIELRDFLKVKLIHSNLIG
                     KYATYSDKKTQPRIAINSREKSTDYKLRNNDLLESTPKNSNITKGKDEVIEVVTLSSE
                     KPINEFQSVSEVLNASVEDDVKNINYLSEDSANDNIQEEFQVDGIKNEGNYYLGDSIK
                     DSEEEYLCSSKRKFSLYGYSVIGVVFNTYIILSKDDSMYLLDQHAAHERILYERYMEK
                     FYRQDINMQILLDPVVIEVSNVDMLQIENNLELFMKFGFELEIFGNNHIMVRCVPTIF
                     GVPETEKFILQIIDNIEEITSNYDLKGERFASMACRSAIKANDKIYDIEIKSLLEQLE
                     KCENPFTCPHGRPIMVEISKTEIEKMFKRIM"
     gene            complement(31318..34161)
                     /gene="mutS"
                     /locus_tag="KOU88_002502"
     CDS             complement(31318..34161)
                     /gene="mutS"
                     /locus_tag="KOU88_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBK3212374.1"
                     /translation="MQIDMNKLTPMMKQYLEVKNRYKDCILFFRLGDFYEMFFEDALV
                     ASKALEIALTGKACGLEERAPMCGVPFHSANSYISKLVENGYKVAIGEQMEDPSTAKG
                     IVRREVIRVITPGTVLDGNLLENKKNNYLLSLYKDGTNIGLTYVDISTGETNATCLNE
                     DKVIEEIAKIHPTEIIINDLDFIENLRDIATVSNIYINESFSDNYLDINILKEYFPDV
                     YLQKLKFDDKGLIKSSLSILLNYIYNTQKQITSNINNINIYNSSEYMVLDMFTRTNLE
                     LTQTIRGNKKKGSLLHVLDKTSTAMGGRLLRKYVEEPLINKSKIENRLDVIEEIKDDF
                     ILREDLNDILKNIYDIERICGKIAFERVTPKELIHLKNSIEKLPNLKDTINLSNAKIL
                     KEYVSEMDKLDDIYNLIDEAILEEPTITIKDGNIIKSDFSDELKELREISKNGAFLVK
                     EIENREREKTGVKSLKIGFNKVFGYYIEITKANFKQAKLDETYIRKQTLSNAERYITP
                     ELKEIEEKILHAEEKIKSLEYEIFVEIRDTIYKNIDRIQKVAKTIANIDVFVSLATVA
                     HINNYVKPAINENNKLDIRNGRHPVVENIVGEENFVPNDTYLNRGENIINIITGPNMS
                     GKSTYMRQTAIIALMAHIGSFVPAESADIPILDRIFTRVGASDDLSQGQSTFMVEMNE
                     VSLILKNATERSLVILDEIGRGTSTYDGISLAWSIVEYIQKNIRCKTLFATHYHELTD
                     LEEEFKEVKNYSIAVKEDGEGIIFLRKIIPQGADKSYGIYVAKLAKLPDEVIERAKYI
                     LKDLEKNHVYNSVAINGDKENNNIINSNLDEELVKVNQSNFKNKYESLKIEHELIVKD
                     YKHIKKDYDKLNSKFKALNDEVALIKQNDDKEKINQVDSVKEVALTQISFDSVNRDIL
                     SEEILNLDILNMTPLDAINSLYNLQRKAKEIKS"
     gene            complement(34321..35055)
                     /locus_tag="KOU88_002503"
     CDS             complement(34321..35055)
                     /locus_tag="KOU88_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212375.1"
                     /translation="MLTQMNFYHNKKVKVSIENVSKTYKDIEVLKDISIDVYEGEFVS
                     ILGPSGCGKSTIFNIITKLTDYDSGKVNINGKYSYMYQKDLLLPYKTIIDNVSLPLIL
                     KKEKKSKARSMVKPYFEVFGLSGYEDKYPSELSGGMRQRANFLRTFINSNDIMLLDEP
                     FGALDSLTKTSMQKWLLDVKKKVNSTILLITHDIDEAIMLSNRIYVISKKPSIVKKEF
                     VIDSRKLNEDNLENIIKLKKEIISLL"
     gene            complement(35024..36037)
                     /locus_tag="KOU88_002504"
     CDS             complement(35024..36037)
                     /locus_tag="KOU88_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3212376.1"
                     /translation="MNFKKLGILGLVSVFTLATITGCSSNNNKDKNNDKDTSSKKVTM
                     VLDWTPNTNHTGLFVALDKGYYKEEGLDVEIVQPPESGAETLVATGKADFGISYQEQV
                     TYAKTSEDPLPIKAVATVIQHNTSGFASPKEKNITTAKDFEGKTYGGWGSPSEEAVFK
                     AVMKKNGADFNKLKIVNTGQDDFFAAMKTVDFAWIFEGWDAVKADLIGYDLNFIPVKD
                     LDERLDYYTPLIISNETVLKDNPELAKKFLKATTKGYEYAIKNPEESAKILVKHAPEV
                     DEKLALKSQEYLASKYKDDAPRWGEMKDSVWNNYTSFLKEYKLIDKDMKASDAYTNEF
                     LPQ"
     gene            complement(36059..36829)
                     /locus_tag="KOU88_002505"
     CDS             complement(36059..36829)
                     /locus_tag="KOU88_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212377.1"
                     /translation="MKNLEIIDKVKDSIYPIATFLFILILWQSMVGVLEVPQYILPTP
                     VDIINVFFKDYQNLSMHAVVTIGEAILGFIVAIIISLVIGILMDFVSIIKKCLYPIML
                     VTQMIPTIIIAPLFMIWFGFGTMPKVLMVMLTCFFPILISFVDGIENIDKDYLNLFKT
                     MDSNKVNTFIHLKFPMAMDKFFSGLKISATYAVMAATVAEWLGGTKGLGVYMLRSKSA
                     YALDKVFASTILVVIFSLMFVGIVQAVKKVVIRHRLID"
     gene            complement(36804..37094)
                     /locus_tag="KOU88_002506"
     CDS             complement(36804..37094)
                     /locus_tag="KOU88_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HBK3212378.1"
                     /translation="MVIADIAVMPLRPYKGEEEMYKVVDACIAEIEKSGLKCEIGAMS
                     TTVEGDFDEVFELLKKVHKIPFNLGCERVITVARVDEKAGGLTIDEKLRNHR"
     regulatory      complement(37225..37324)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     regulatory      37944..38033
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            38086..38262
                     /locus_tag="KOU88_002507"
     CDS             38086..38262
                     /locus_tag="KOU88_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212379.1"
                     /translation="MFMDKMDRCTHILTAYICSSRDYCNFIDTQLNDFILEYGENVVE
                     SCLHQVMVLVSRYN"
     gene            complement(38377..38733)
                     /locus_tag="KOU88_002508"
     CDS             complement(38377..38733)
                     /locus_tag="KOU88_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212380.1"
                     /translation="MDIDNNFEEFPNIEERQKDFNCSIGFTMTVIGSKWRAIILWHIL
                     KQEPIRYSQLKKEVVHISHKILSQELKYLERDGLIKRISYPTIPPKVEYLSTKRGKSL
                     ESILLELCNWGKQYMR"
     gene            39200..39948
                     /locus_tag="KOU88_002509"
                     /pseudo
     CDS             39200..39948
                     /locus_tag="KOU88_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816229.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis isomerase"
     gene            40179..40790
                     /locus_tag="KOU88_002510"
     CDS             40179..40790
                     /locus_tag="KOU88_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBK3212381.1"
                     /translation="MINDIKNKFKNYKPYINGYKNMKRASVLIPIVEINNTHYILFEV
                     RSKNLKHQPSEISFPGGKIESGETPYEAVIRETCEELGTFSDNIEVISSLDLLITPVK
                     FIIHPYLGYIKNINNLNINKDEVDHTFLVPIKYLLENPPNTYSNTVKVFPDENLPYGS
                     IPNQKDYKFESGSYPILFYKYKDYVIWGMTAKILENFLNFLSE"
     gene            41088..41426
                     /locus_tag="KOU88_002511"
     CDS             41088..41426
                     /locus_tag="KOU88_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3784 domain-containing protein"
                     /protein_id="HBK3212382.1"
                     /translation="MFAVGFVVIIALAFFILSVLLFNGKASMLLAGYNSMSKKEKARY
                     DKKKLCRSSSIVTFIVSIMLFIMAFLGYRIESGQMDEKKMVPFSIIFIIVILSSVFFN
                     ILYSNKKCKK"
     gene            complement(41833..43269)
                     /gene="miaB"
                     /locus_tag="KOU88_002512"
     CDS             complement(41833..43269)
                     /gene="miaB"
                     /locus_tag="KOU88_002512"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBK3212383.1"
                     /translation="MSKRKQVTIPIEKIQEQDKYIEQIHRQNEEYFNRTGKRKLVFTQ
                     TFGCQMNEHDSEKLCSMLEEMGYQMSMMVEESDLIIYNTCAVRENAELKVYGNLGQLK
                     HLKGKNPDMKIAVCGCMMQQPHVVEELRKKYKHVDLIFGTHNLYKFPQLLTESINSDK
                     MLVDVWDVDGEVIEGLRSNRKFELKAFVNIMYGCNNFCTYCIVPYTRGRERSRTPEDI
                     INEIKELVANGTKEITLLGQNVDSYGKTLENPVSFSELLRKVNDIEGIERVRFMTSHP
                     KDISDEVIYAIRDCDKVCEFLHLPIQCGSSSLLKKMNRHYTKEYYLEIIEKAKKEVPG
                     IAFSTDLMIGFPGETEEDLLDTLDVVEKVRYDSAFTFIYSKRQGTPAAKMENQIPEDI
                     KHDRFNRVLEAVNRISAEINDGYKDRIVEVLVEGRSKNNENKFAGRTRQNKLVNFEGG
                     NDDLIGKLVMVKITEPRTFSLNGILVNN"
BASE COUNT        14790 a         6701 c         5034 g        16828 t
ORIGIN      
        1 taaatccttt tgataacata taaaagtaag ataaattttt ccattaaata ccttataatt
       61 atacacaaaa tctctatata cgttaaacag tatagagaaa attttcatag aaccatcttt
      121 ataggggata ctttataaaa gaataaaaaa attataatat ataaaaactt cataggagag
      181 taacaacatc agtaaaaata tgaaaacact atataaaaat tcaaaaatat taagaataat
      241 gaaatacttg aaattgctta tatcaagaaa ttttatataa tataaactgg tcaaatatgt
      301 tataatatta aattgtgaca agttcatgga ggtgtttata tgaaaaaaca aaagtcgcca
      361 attttacttg aaatgcttgg actatttttt ggttgtatat caatgagtat tggtataaat
      421 atgtttttaa aaccacatac aattgctcct ggaggactta gtggtctatc attagtacta
      481 aacaaggtta caggacttcc agtatcagct atcatgttaa ttataggtgt cccattagta
      541 atacttgctt ttagaattat gggtacaaaa aattcattaa aaactttatt tggaacagtt
      601 gtattttcag ctatagttca attaacagac ccattatcaa aactaagatt tactaatgac
      661 ttattattgt cttctattgc aggaggaatc ctagttggta taggtttagg aataatgttt
      721 aaatcagatg cttctactgg aggaacagac ttaattgcac tcatacttag taagaaattc
      781 ccaggaataa aagctacaaa attcatgtca tgcctagatg gaatggttgt tatatcttct
      841 ggtatagtaa atcgtagttt agaaactgct ctttactctg gtatagcact ttgtgtatta
      901 ataaaaatag cagatatgat aatggaagga tttgaccatt caaaagcatt ttttattatc
      961 tctgatgagc ctgaaagttt aagacaagct ataactgaag aacttgatag aggtcttact
     1021 attcttgatg gtaaaggtgg atacactaga gaaaataaag aagttctatt agtcgtagtt
     1081 tctaaaaaac aagaacttta tctaaagaga ttagttaaaa gaactgaccc tactgcattt
     1141 gttattgtta cagatgtaca tgaggttctt ggagaaggat ttaaaaattt agagaactaa
     1201 taaaaattaa tattttaagt atatatacta ttttaattaa aatacgattt attcaaaaag
     1261 agtgtctcat aaacttttta gttcatgaga cactcttttt tgtataaaat caaatgcatt
     1321 ttcagtattt taacaataaa aacaggatta tctatatttt gaggcaacca ctttattgaa
     1381 attttattta gaaaacaatc attactaaat aaccagcata gatattaaat gattatatct
     1441 attgtttttt caattcatat tgataacaag gaacattttt cacagtattt ccagtatgaa
     1501 tttttttgat atactttcct gtacatttaa atcctaataa atctaatgat tttgtagaat
     1561 tttggttttc ttcataggtt attgcaatta ttttatttaa gtttagttct ctaaatccat
     1621 actgtattac tctttttgtt atctcagtag caaaatcatg tccccaatag cttggattta
     1681 tacatatacc tatttctgct tctaatgctt taggatttat attattaaac cccatattcc
     1741 caataacttt attgtctctt ttatatacta tagcaaagtg gccaattttc ccttttttat
     1801 atggatttag aaaaaatgat tttataaact ttcttgtatc ttctaaagat ttatgctcac
     1861 taaatggtaa atgttttact actattttat ttttataaca gtcaaaaaaa tcttcaacat
     1921 catctaatga tgcaggtctt agtatacaat ttctagtttc taaggttttc atttgaggat
     1981 attcagaatc agacatttct aatccccctt tatacattaa tctaaatata ctgttcatat
     2041 ttaaaatacg atattaatta tataaatgtt ctcaaattaa ccttattttt atttttaata
     2101 aaaactaatt actatatgaa tctttcaaat ttacgaattt atctctattt ttatattaaa
     2161 ttacttgtga aatatgtatt ctaaattata tattattaga tatcatgctt aaaaattctt
     2221 tggttgctaa ggataaagat atatctttta aatggcagta acctatattt ctcttaggta
     2281 ttggctcttt tatatctaat ttaaacaatt tctcattttc caaataatct atgctaaatt
     2341 cttctataac acaagacact ccaagattta tatacgcaaa ttctaaaagt aattcatgag
     2401 aacccaattc tatatccggg tttagtttta taccttttga taaaaaatat tcatttacat
     2461 aaagtcttga atttgcttta ttttctagca ttattaaagg caatgtgttt aattcttcca
     2521 atgatatttt cctacctttg tattctatgt aatcatttgc acatacaaat atatcatgta
     2581 tttcaataca ttcaacaata tttagtgtat catcttctat tggcatgttt ataattgcta
     2641 tatctatatt cccatctttg agtaaagata taagttctct actcgttcta tttattgtag
     2701 atacatgtat atgtggatac ttcttatgaa aaatttctaa atattttaac aagaaaaaac
     2761 gtgcagctgt atctcctact cctattttca gagaaccgta ttctaatttt ttaaatttat
     2821 ttattctatc ttctcctgat gatattaact ttaatgcagt agtgacatgt tcacttagaa
     2881 ttttcccctc tggagttaat tttactccct tattgtttct ataaaataat aaagtatcta
     2941 attgttcttc taattgcttt attgactggc ttacagctgg ctgtgacata aacaattcct
     3001 tagcagcaag agaaaaactc ttattattta caactgcatt aaaaacctta taaagttcaa
     3061 gttttatatt catatataat tactccttat gtcaaatatt agtattattt attttactta
     3121 taattatatt tgaattataa tatacatggt actaatatga caatattaat tctttaggag
     3181 gattttagat aatggataga ttagttggaa ctgtttcaag aggggttaga gcacctatta
     3241 taagacaagg agatgactta gttaaaatag ttgttgattc tgttttaaat gcgtcaaaaa
     3301 gtgaaaactt tgaagttagg gacaaagatg taattgccgt tacagaagct gttgtagcta
     3361 gagcacaggg aaattatgct cacgttgaca atattgcaaa agatgtaaaa gataaatttg
     3421 gagatgatac tgttggggtt atattcccaa ttttaagtag aaatcgtttt gctatatgtt
     3481 taaaaggaat tgcaaaagga tgtagaaaag tcgtattaat gttaagctac ccttctgatg
     3541 aagttggaaa tcacttaata agtattgatg aacttgatga taagggaata aatccttggt
     3601 cagatgtttt aacagaagaa aaatacagag aactatttgg atataacaag catacattta
     3661 ctggtgtaga ttatgttgat tattataaga atttaatcaa ggattgtggt gcagaggtag
     3721 aaatagtatt tgcaaacaat ccaaaaacta ttcttaacta tacaacaagt attttaactt
     3781 gtgatataca tacaagacaa agaacaaaga gaattttaag acaaaatgga gctaaaaaag
     3841 tatattcact tgatgatata atgacagcaa gtgtagatgg tagtggttac aatgaccagt
     3901 atggactttt aggttcaaac aaagctacag aagaaacagt aaaattattc cctataaatt
     3961 gtgatgaagt tgtaaacaaa atccaaggta atataaaaga aataacaggg aaagatgtag
     4021 aagtaatggt ttatggagat ggagctttta aagaccctgt aggtaaaata tgggaattag
     4081 ctgacccagt agtatctcct gcttatacaa aagggctaga gggaactcca aacgaagtaa
     4141 aattaaaata cttagcagat aatgattttg ctgacttatc tggtgatgag ttaaaagaag
     4201 caatttcaaa atacatagtt gaaaaagata ataaatctga tgatttaaca ggaaacatgg
     4261 tttctcaagg tactactcca agaagattaa cagaccttat aggttcttta gcagatttaa
     4321 catctggaag tggagataag ggtactccta ttatttacat acaaggatat ttcgataact
     4381 atacaaaata gtatgtttta ataagattta atttttttgg attatatata ttaacatgaa
     4441 aatttattaa aacctcttaa tagatatgac ttttcaagag ttatatttat taagaggttt
     4501 atttaatgtt cacagataag atatatttaa ataatttaaa caagattgtc agaaagttat
     4561 ataatcttaa aaatttatat aactctaatt cttatttatt tctgaaataa tatcactctt
     4621 caaaatttgt cttactggaa taattacagc aactatacta atagtgatat ttaaaataat
     4681 catacctatg tataaaggtg tatttatttt aagaattgga tttatatata aatatacacg
     4741 ttttaccata aaataaatca taaattgtcc aataacactt ccaattacca ttataatact
     4801 tgcatagaat ccatataaaa aaccttctct tatcatcata agtaaaaact tattatccgt
     4861 aatacccata gctcttaaaa ttccaaactc atgtcttctt gaaaaaatta agtagcttac
     4921 tgtattgatt atatggaaca aacttattgc aagaagtaca aatacaatac catatataaa
     4981 taagagtttt tgatttaagt aggtattatt tttttcaata gcaatggtat aatctgttac
     5041 gatacatctt tttacatcac ttacaacact ttttatgttc tcagacaatt cctcactgtt
     5101 actatcttct gtctttttta tacttactga attataattt tcgatatcaa agttattttt
     5161 catttgacca ttcgtcataa ctatatccat accataatca ccaatgaaat atatgttatt
     5221 tgccatcaca cgttttacag tagcagcaac tacaaattct tttgttgtat aatcattctt
     5281 attttcttct ttaaatttaa caatttcatc tgttggtttc attgtctttg gcactttaac
     5341 ttttattgta tctcctggat ttatatcaac tgcatcatac atcccagttc catccatagg
     5401 tagtctaact ataaccttat tatttttaac catatcatgg gtattaatct ccccatctat
     5461 aatataagaa tttaatcctt ctaacatacc attgttataa ccataaatat ttgtttttaa
     5521 aagatagcca ccttcatttt gctttgtaca aataccatca aaaaaagtct ttatcctgta
     5581 atctttttca agaggtttaa agaaattttt ccaaaatagt tgttcttctt taatttgcat
     5641 agctccaaat aaatatctta ctggatagac ttttgatatt ccctcaacat tgtttaatct
     5701 tgaaatttta tcttttggta tacctacatc aaaatctgtt gtttgcatag ttatttggta
     5761 gtcagaattt aaaccatcat cagctttcat tgtaagttca ttattatttt tagtaagctg
     5821 tatagagtaa ctagaacata gaaatataat tccaccaagt gataatgaaa acaaaattcc
     5881 aataaacatt cccttttttt gagtcatgta tttatgagat aatacttttg tcatgttaga
     5941 gtgttttaca ctttctaata ttctcttttt cttattagta atcttaaagt ttttcataga
     6001 ttctatacta gagtatttat tcaactgatg tacaacacgt acagcaatta aaattaacaa
     6061 caataagata aataaaaagc ctaaataaat agatttttca cttataaaaa atgctcctgg
     6121 aacaatatca ctactcaaaa atatatgtgg aaattgttca tatattgtag acgctactcc
     6181 aatacctaag aagcaaccta taggaaatcc aacaataaaa agtaaaaata actctaaaaa
     6241 tagtagaaat aaaagttgtt tattattagc gcctaatact tctaaaaccc catattgtga
     6301 tattctctga agtattgaaa catggaaaat actatatact gctgctgcac caaacactcc
     6361 aacaagcaat ataattgcat ttgtatttag ttctaaattt tttaagaact caaatatatt
     6421 atatttttct atattttttg gtggttttac tccaaattca actgaaagag accagtttat
     6481 ataagttttt tcttttgata tgttgaattt tttcataaat ttataatttt gctttttaat
     6541 atttttattt tcatcatatt ttacataaac tatataagaa tccttttctt taggctgaaa
     6601 ataatcgttt acaaatccct ccagagcagt ttctgggttt gaaagacttg ataaaatacc
     6661 acataactta tagattttac catctaaatt gatttctgtt ccaatttctt tgtttacatt
     6721 taaattgttt agagaatatg tgtcaagtac tatctctcca tctttactag gaagagttcc
     6781 ttttaataat tttctacctg tcatgtctaa atatgaagaa tcagcattta aaaattctat
     6841 aataaaaggt tcatctatct gatttttagg ttttgtaacg ccaagtctat ctacagtgta
     6901 ttcctttgat tttttatttt ctttaatttt attaagttgt tccttatcta ctttatagaa
     6961 ataatgataa tctccactat cttcccttat cttttcaatt ctacttttgt ctgcactatg
     7021 aactaaagaa ccaattcccg tcaataatgc tactgatagt actatgctta aaactataga
     7081 tatagattgt tttttataat gctttatata ttgaattgaa aattttacta gagacatcat
     7141 agtaattcac caccagtatt aaccacaact ccatcttcaa tatggataat tgagtcgcat
     7201 acttgtgcta tattttcatt gtgtgttacc ataagtatcg tttgatggaa ttttgcacta
     7261 ctttctttta ataaacatac cacttccatt gtagttttac tatcgagatt tcctgttggt
     7321 tcatctgcta atataagcgc aggtttattt gccaaagctc tagcaattgc taccctctgt
     7381 tgttgaccac cagatagttc gcttggaaat tttaaacgct tatcccaaat tcccaatgtc
     7441 ttcatcagca tttcaatata ttcatggtct atatggtttc ctttatctaa tgtaacagga
     7501 agagctatat tatcataagt gtttaatacg ggcattaaac tgtagttttg aaatataaat
     7561 cctatatttc ttcttctaaa cactgtcaaa tctttttttc ctattttaga tatgttcttt
     7621 cctttaatta ttacatcacc tgaggttgga ttatctaatc cacctataat atttaacaat
     7681 gtgctttttc cagaaccaga agttccaact atagcagtaa atgtatctcg ttcaatttct
     7741 atacttactc catttaaggc ttttacttta gtctcacctt ttccatagtg ttttactaaa
     7801 ttattcgtca ctaatatact catttaattt ctcctttcaa tacagatata tgttctataa
     7861 aatattgtaa gtgacgataa ttacactcat cctacaaaat tagtttaaac tcttacaatt
     7921 ctgtaagaag atactaaaac aacatccact tcctagttta gattctacta taatgtttcc
     7981 attttctttt tctaaaatta atcttgtaag atatagacca atccctgtgc cattttggtt
     8041 ttcaacattt ttacttctgt aaaatctttt aaaaatatca tttagttctc tactatcaat
     8101 acctattccc tcatctttaa tagtaatctt cgtatatagt tccattttta ttacagaaat
     8161 agtaatcgtg ctatctgatg gtgagtattt tattgcattt tctaaaacat ttacaattgc
     8221 ttctatggtc cactttttat tatgaactaa ttttatgtct gaaaatggtt cgagatttat
     8281 ccttatattt ttagcttctg ctttattaaa gatagtactg atactttgaa taagagtatc
     8341 tttaattagt agttcttcta cttcaaattc tataactcca tcctctaatt tagtcatttt
     8401 aaataaggat tgtaacagcc agtcaatctt aaaagtttca tttttcatct tttgtaaaaa
     8461 ctccttcttc tgtaatgtgg aaatatttat attctccaga agttcacaat aaatggttat
     8521 atttgaaagt ggagttttta attgatgtga catatttgat attaaacctt taatcgcttc
     8581 tttttctgac tttgactgtt ctacctctat ttctatcata tccttaattt tttttacttg
     8641 gtgagaaatt tttgacgctc ttgtatcctt tgtatctgga taagtaactt ctttaccttc
     8701 caatatttga tttaacatca aatttaattc atcatatctt tttcgattta ttttagtaga
     8761 tactataaat ataacaactg tacatattat aaaggctaat ataaacatat tattctacct
     8821 cattccataa ataacccatt ccataagctg tttttatata ttttggatta gatgggtcat
     8881 cctctacttt tactctaagt cttcttatat ttacagatac aatattatca tcaacataat
     8941 tttcttcgct gtcccaaata tggtgtaaaa tttgttcctt taataatatt tgacctttat
     9001 tttcaattag ataacttaga agcttatatt ctacagagct aagttccaaa cattctttat
     9061 ttttatatac ttttagtaac ttttggtcca attttattcc attggaatat attactttat
     9121 tattcgattt ttttcttatt gctactttga ctcttgcctt taatacagat aaagaaaatg
     9181 gttttgtaat gtaatcatca agccctattt ctaatccttt tacttcatca atttctgagt
     9241 ctcttgcagt aagcattata attggtatat ctgacttttc ccttattatt tgacatacat
     9301 caaatccatc tccatctgga agattgcagt ctaagattat aaaatctata tttttactat
     9361 taaatatatt taatccttct tgttttgtat aagccttaaa tacattaaat ccatcattct
     9421 caaatgcata aaaaagacct tcatttaagt ttatatcatc ttcaataatt aataagttca
     9481 attttactct cctttagatt ttttagataa ataattattt tcttgcatta tcatactaaa
     9541 aatattttaa ttttatttat ttcactaaaa agattgtatt taaatttgtt ttcaaaataa
     9601 aaacattata atcaagcata tagttatata tttcccaatt taattacgct taaattgaaa
     9661 atataacttt attcttatat aattaaatta tacaacaata aagttatatt ttttaaatat
     9721 atttttacta gggggaatag aattgaaaag ggttgatgag agaaatacta tgtttgcaag
     9781 agcaaattac aaaaaagata gtactgctta taatgactat tataagaaaa atcctgacaa
     9841 aaaagaaatt gatgatagta taagaaatag accaaattta tgtagtgaag gaacaatgac
     9901 ttacaatgag ttaaactctc caatggcaag tagtgcattc gattttttat ctgatatcaa
     9961 atctttatgc gaaggaaaag tttctgatac taaagtagat gtagatgcaa agtcaatgac
    10021 aaaaaaaatt aagggtcttg caaagcagta tggagcttct gtagttggta taactaaatt
    10081 aaaagactat catatttata caaatagggg tagacatgaa gaaaattacg gtgaagaaat
    10141 taatctaact cataagtatg caattgtatt tggatgtgag atggataaag aaatgataaa
    10201 tagagctcca atgatatgtg aagttataga aacatcaaag tgctatgtgg atgcatctat
    10261 cgtcggcatg attttaagtt actatataag aaatttagga tatgatgcta gaaatcatat
    10321 ggatgctaat tatttagtaa tgcctgtttt tatagctcgt gatgctggtt taggagatat
    10381 aggaagaaat gctatactta caaataaaga ttatggctct agacttagat taggtgttgt
    10441 tactacagat attcctcttt tagaagatga atatgttgat tttggactag aagatttttg
    10501 taaggtctgt aaaaaatgct cttttaactg cccttctcat tcgctttcta atgatattaa
    10561 aattggtgat gatggaaaat ataattgggt aattgaacat gagacatgct atattaaatg
    10621 gagatattta ggtacagatt gtggtatgtg tatatctgct tgcccattta gccaaaatct
    10681 cgaaactata aagaatacta cttcatttaa gggtaataat gagcttattc aaaaagcttt
    10741 agatgagtat acttcaaaat ttggtaaaag aatatttata cctggaaatc catcttggtt
    10801 gaaataattt tatttaataa agaatctgta ctagaattta tcataggaca ggttctttat
    10861 taaatatata aatttttaaa tactttttct cgtttataac aattcagcaa tgtttttagt
    10921 ctataattga cattataaaa tattaaacta aaaggagtaa ctgtatggaa aaaatattag
    10981 tagtagaaga tgattctata ttaaataaaa ctctatcata taacctaatt gaagatggat
    11041 atataattac ttcaaaattt acagctaaat ctgcactaaa gtctattttt gaatgtgaat
    11101 ttgatttaat aattttggat attaatttac cagataaaag tgggtttgaa ttatgtaatg
    11161 aaataaagga aaattacaat ataccaataa tttttttaac tgctaatgat atggaatgtg
    11221 atatgattaa aggctatgaa cttggagctt tggattatat aacaaaacca tttaatatca
    11281 atatatttaa acaaaaaatt aaagcttttt taaatcatct tacaataaaa acaaaacaag
    11341 attactatag ggatggatat cttgaaatta acttttctga gttatctgcc aatataaatg
    11401 gaaatcaaat tatatttaca ccattagaat atcgtacttt aaaactgctt actgaaaatc
    11461 ctaaaagtat tttaacaagg aaagtacttt tagaaaaact ctgggatata gatgctaact
    11521 ttgtagatga acatacttta acatctgtta taagtaggat tagaagcaaa attgaaaaag
    11581 acaatcttaa gtatatcaaa acggtatatg gtatgggata tatgtggtta ggtgaaagaa
    11641 atgaatttta aaaaattttc ttttagttct atttatttaa taattgctgt tggtataatt
    11701 tttacagcta ttttatttag tatctcaatt tatctaataa ctgatgattt aaaactaatt
    11761 gctctattat taatatatac aatagtactt tgtggattta tagcattaat aatattttta
    11821 cttcataaaa aaatagttat attttgttct aaaatatgtc acactttaga tagtatgatg
    11881 aatagtgaag ataatattga aattgaatta gaagaagaaa ctattttatc acgtatcaat
    11941 cacagattaa ttagaatgta tgaagttatt caagaaaatc gcaatagtat tgctatagag
    12001 aaagctgatt tacaagaact agtttctgat atatctcatc aaattaaaac tcctattgca
    12061 aatttaaaaa tgattaatac tactctacta aatcaaacat ttaaaacaga aattcaaaag
    12121 gattttttaa tggatatgga aaaccaatta gataaattag attttttaat gcaatctatg
    12181 gtaaaaacct ccagactaga gacaggtata atcacactat ctaaaaagaa aaattcaatt
    12241 tatgaaacaa ttgctacagc acttagtgga attttgtttg atgctgaaaa aaagaatatt
    12301 gaagttacag ttgattgtga cccaaattta tatataattc atgacaagaa atggacttct
    12361 gaagctattt ttaatatatt agataatgct gtaaaataca caagttctaa tggtaagata
    12421 cgtgtagcta cagaatgttg ggttatgtat acaaaaatag atattattga taatggaaaa
    12481 ggaatatcag aaagtcgcca agcagaaatc tttaaaagat tttatcgtga agaagatgtc
    12541 catgacatag aaggtattgg aataggtctc tatctttcaa gaaaaattat atctcttcaa
    12601 ggtggctata ttaaagttac atcagatatt ggaaaagggt cgactttttc tattttctta
    12661 cctaataaat aaatttttaa atatttcatt tgtaatgatt ctgcaacatt ttggttttat
    12721 actgtattta caagatgtta aggaggtatt attatgagta ttttacaagt aattaattta
    12781 aagaaatatt atggacaaag ttcaaacatt acaaaagctc ttgatggtgt aactctatct
    12841 attgaaaaag gcgaatttat ttctattgta ggtacatctg gtagtggcaa atccacatta
    12901 ttaaatatga tgggaggatt agataatcct acatctggaa aggttattat aaagggtaag
    12961 gaattatcta ctatgactga tgaacagctt acaatcttta gacgcagaaa tataggtttt
    13021 atatttcaaa attataatct tgttccttta cttaatgtat atgaaaatat tatcttacca
    13081 ataggattgg atggagagac catagataag gattttataa atgaaattat aaatatgctt
    13141 tctcttgaag aaaaattata tgatatgcca agtaatcttt ctggtggtca acagcaacgt
    13201 gttgctatag ctagagcact tgtaacaaaa ccagctatta tactagctga tgaaccaaca
    13261 ggtaaccttg atagtagaac tagttcagat gtactgagtt tacttaaagt gacaagtaaa
    13321 aaattcaacc aaacaattgt aatgattaca cacaataatg aaattgcaca actaactgat
    13381 agaattattc gtattgaaga tggaaaaatt gttaactagg aggtgtagta tatgtttaga
    13441 aataataatc gcacatttat aagaaaaata gctttaaatg atttaaaaat taataaactt
    13501 aaaacatatc tttcaggtat cattataatg atttctacat gtttattatt aacagtgacc
    13561 ttagtttcat ataatgcctc tgtagattta gttaatgcat ctccatatca tgctatatat
    13621 aaatctgtag atgaaaaagc aaaaaatata ctatataaag ataaaaactt tagtggcgta
    13681 ggaacttaca aattaattgg aagtaataaa aagacagatt gtattatgtc gattgtttat
    13741 gcagatgata cagcaattaa acttatgaat tttcaaccat tgaaaggcaa actacctaca
    13801 aataaaaatg aaattgctat ttcagaaaaa tatttacagg aatttggttt agataaagat
    13861 attggagata gcattaaatt aaattattat gatgatatta cgaataaaga agttcaatgt
    13921 gattttatta ttgttggatt tctagaaaat tattatcaag ataatgccaa gcaatactat
    13981 acagtcgttt caaatgatta ttttaagaat atagcttcta cacctttaca aaataaaagt
    14041 aatacttttg acgagtcaag acctgatact gtagatgtat tagttaaact atcagaagaa
    14101 aatacagaga aagattcagc ttcaattaag acacagttaa agaaaattgg tttatcttta
    14161 ggtattaaga aatataatat atacttaaat gataactata ttgaatcaaa tttaattgat
    14221 ggtgagcaga ttattacagt tttagtagtt ggaatagttg ttcttttttc tagcgttttt
    14281 gttatatata gtatttttta tatttcagtt gttaattcgg ttcagatgta tgctaagttg
    14341 aaatctttag gtatgacttc ttttcagtta gaaaagatta tttctctaca aggaaatatt
    14401 ttgtcaatta tttttattcc attaggggtt atagcttctt gtataattgc ttacataatt
    14461 caaccattag catggcaaat gatagctgat ttatttataa ttttaatttt atcactggta
    14521 atgtttttaa ctgttagaat ttctttattt aaaccagcta gaattatttc taaaatatct
    14581 gctattgaag ccatgcaata tacagaaact aaatttagaa aaaaagcaaa aaattttagt
    14641 tatataaata taaaaaatct agcattaaag aatatcgagt caaatagaaa gaaaaatttg
    14701 attgcattaa tatcgctaag cattagtgga gttttattta tttcaatcgc taatcttgct
    14761 aattcaatag atttcaaaaa acaactatct caacaatttg tctataacga agattatata
    14821 attagcatta agagtgataa cttatatgag catattacag aaatccaaca aaataatcca
    14881 ctaacagatt ctcttaagaa tgaaattaaa tctattcatg gagtaaaaaa attaattgaa
    14941 tccaaatcaa ttaaaagtaa tattatagaa ccttacatca aagatagaga cgaaaaacaa
    15001 tttattactc taattaaagg tattacgcct gaactttcaa aatcacttga agaatatatt
    15061 gtcagtggaa aaatagacta tacacattta gattcagata gtttaattat aaataaatat
    15121 agaacaaaat attatggatt aaatttaaaa gttggagata cagttacatt taatatcttt
    15181 agtggaaatg atattattaa aaagaaaatg aaaattatag gaatcattga caattccaat
    15241 acaggaggta tgttttttgc ttcagacaaa actttagaat ctctaacacc atataataca
    15301 aatttagatt tttctatttt aatagataaa aagcattcta aagaagttga agaaaagttg
    15361 ttaagtataa ttcagaaaaa ttcaaattta atgctttatt catatgaaga tgattataga
    15421 atgattacta gagcatttca atatataatt atagcttcat acatttttgt tggtttaatt
    15481 tcttgctttg gtatactaaa tatgaccaat accctaataa acagcgtttt aattagaaaa
    15541 aaagagtttg cattacttca agccgttgga atgacaagaa agcaactgcg aaatatgctt
    15601 tatagagaag gtctaaacat aagtatcaaa gctatatgta cttcaagtat actaggttat
    15661 tttggttcaa atctactttg cacttttata aaagatgtaa ttagattaga ctttattaat
    15721 tttaaatttt ctatatttac tattttaatt ttttcattcg tattaattgg tatacaagtt
    15781 ttagtgactg aattacttgt aagaaatata gaaaaaaaat cacttacaga acgcttacgt
    15841 tctcagtaag aatgtatata aaaaatagcc attttttata caagttttaa cataattttt
    15901 taaaagctaa agggatagaa aattttgact ttacataatt ttctatccct atacttgttt
    15961 ttattttata cagatacact tacttatatc tccgagcaac atcaccagag acataaacaa
    16021 gcatattcct tattttctaa atatgtcaat tgcatgactt gtaaccccta ctaaatcttc
    16081 acgttcacaa gtagcaaggt gatattttaa atataatgca aatgcatcat catccataga
    16141 gtctactgct tcacgcatat acaaagccaa accatctgat gcgacataat gcagtctagt
    16201 tacattaaat gcagacatca aatcatcaat gttttcttta cgtacaagct caaacaaatc
    16261 ctttggttca gacttagcag caaatgtctg tggatcaatc aaaccttttt caatatattc
    16321 agatacatta atatttcctc tatggaaccc ctcgtcaatg agacagccat cagatataac
    16381 atatgcagca aaaaccacac caccaggttt tgttacacga attgcctcat gtaaagcttg
    16441 ttgtttatct tctttgttat aaagatgata tagtggtcct aacagtaacg taatatcata
    16501 tttattatct gggaaaacag ataaatccat agcattaccc tgagtaatgc ttatattttc
    16561 atttgattga gtatttttat ggaaaacctc tatattatgt tcgactaatt ccactgcgtc
    16621 aacatcatat ccctgacgtg ccagtgtgtg agaataacga ccagttgcag cgccaatttc
    16681 aagcacacaa tcacctgatt ttatgtactt atcaatgtaa tgcatagtag tgagaaattc
    16741 caccattcca tgttttaatg caagtcgact atcttcatca taagtattat aaaagtcaat
    16801 taagtattgt tttgtttcca taatttcacc tcttctatat tagttaataa acatcaaata
    16861 gacaaattcc aatctggttt ttcttgtctt ataaaagctg ttaatatatt tttcaacatt
    16921 ttttcagcac tatatctatc taatgttaat ttttttgttg ctgttaagac agctatgcca
    16981 tgagtataaa gaaataaatc taaaaatatt acttttgcac attccaactc tattccaatg
    17041 ctttccgaaa aaagtcttgc ctttttttca ttgtcaattt ctttataaaa atcattcgcc
    17101 tctttcatca tcaaatctaa atcatttata aataacaact taaataaata cgtttcttct
    17161 tgagcaaatt caatgtatga aagcggaagc agtaaataag ggcttacact tttagaatta
    17221 cgataattaa caacatactg attataatat tcatatgcaa aagcaagaaa ttcatttttt
    17281 aattcattca tgttttcgta acaagtaaaa attggtcgag tggaacactg taatttactt
    17341 gcaatactcc tcgcatttac agcttcaaat cccacttctc ttgtaatatc caagactgta
    17401 ttcaaaatca tttcttttgt tatctttact ttaggtggca tatatgttca cctctccatt
    17461 aaatttttat aaaacacata cgttatataa ctatagtaac atatcaagaa attatgtcaa
    17521 gaaaaagctt tgcatttttt tgcaattcct aaaacttata aataaaacat gagttgcaat
    17581 taatctatta atagataaca gcaactcata ttttccttta aatactcttc tttttgtcta
    17641 atatttcata tacacaatct tctattgaat taatatcttt ttcttttctt tttttagaat
    17701 caattaaaat gaaatacagt ataaaaccta cagcaagtcc ccatgttccg cctttagcag
    17761 caattacacc tcccataagt ccaatcaatc ccttctcaac acctgtatta catagctcca
    17821 ttgatagctt tgtacataaa tatccttgaa ctaaaagtgt tactgacaat gctaatggta
    17881 taagaggtgt agcaatctgc gcaattggat aaaaacagat aaaaattgct gaaacccata
    17941 ctaatgtacc catgccacta aaaacagact gcatggcttc ctttccaacc ttgtaccttt
    18001 gagcaacact tcctgtaagt gtcgcagcta atggaccgca cattggtata tatggagaaa
    18061 agattgccat aaaaatattt cttatcccac ttataacatt agacctattt gaattgaaat
    18121 ctatatattc atcttttcta ttttcacttt cagaaagtac taagttttca cctgttataa
    18181 aatcaccaaa ggcaattatg tatatcataa aagccattgg tatcccttgt ataaataaca
    18241 ttacacttgg aaaacctatt ccaaaaggag atactgtatt tatcagattt ttaaaatcta
    18301 ctatgtaaac taaattgtca aaactaaatc taggaatttc tatttctcta ctaaatatac
    18361 ctactattaa actcactaaa atagctgata ctacaccata ttctcctaaa tgaaataaaa
    18421 atttattctt aacttttaga gtatcaaatc tttcagaaaa cattacaaaa caagcaacca
    18481 aaattcctac tgttatagat ataggataag aatcaaatct ccctttagga ttaaactctg
    18541 atattatagt cgatataccg acacccatta gtattccacc tttaatagaa tttggtatct
    18601 tactaactaa ctttccagct acaccagtta tacccattaa aataaatatt attcctaaat
    18661 ctatttgtaa agctgttaat gcttgtattc tttcaatgcc catgctgaac tttaacaaat
    18721 atgcagttgt aagagttata gaagctgtaa tccagccagg tacaactggg tctcccataa
    18781 aaacatgcaa acagtataat attgagttaa tgatagccat actccatgcc acttcatagg
    18841 gtaatcccaa aatttgtgta ctaaggccaa ttgtgcctaa acttgtcata cttgatatta
    18901 taccttgaat agcttctggt ttctcaaatc tgtaatgtat aaatggaatt cttatcttaa
    18961 acattccaaa ttttatatga ggttgttccc ttctagcgag tctttccata acttcactcc
    19021 acctttcaat aactcttata agtttacaac tttataattg tttataaatt gtcaatgtca
    19081 ttaaaattag tatataacat gcaaattata taaacaataa attaaatcta taaaattgat
    19141 agattttgtg catatataga aagaccgctt catttttagt tacttaaatc acttaatatt
    19201 agttatttaa atcacttgat aaaggttttt tataaaattc aatagttcta ttccatgatt
    19261 caaactgtcc ttttgaattt ccttctacag ttccacctga agaaaaaatc cctccactca
    19321 tactcataca taaagtctcc tttagaggca taatatatgg aattggtaac ggatgaccca
    19381 tattattgta tgttaataat tctacgttat atggataatt attttcttca aagatttcta
    19441 atgtctctaa acaagcttca taactattcc atatgttatc ttcttttcca gcaatcataa
    19501 gtatatctgc tttggaattt tctattttta ttctagcctc ttttctattc tctgctcttt
    19561 taagactttt cttataagta ctattaaatc caaatggaat accttttgat atattttttt
    19621 tctgttcttc aaagaatata tcattgtcta ctttgatata tggaaatggc tctcctttat
    19681 atgaccatga tgaagtatca tttccactca tcaatccatt aagagcttgg aaacaataaa
    19741 tgtgaggttg tgatactaca acctttttaa tttgttcata tcttgaagca agtaaaaagg
    19801 ccaattctcc accctttgat gtcccatgta caaatatttc tttagtactg gtaatttcat
    19861 tttcactaat ccactcaaat actttttcaa aatattctaa tggaacctct tctaatttat
    19921 ctggtaaccc ttctaaagca aagtatgcaa ctgttagtac attgaatcct ctagatgcaa
    19981 gtggagctgc taaaaggtct agagcgtcta aatttccatc agaaccacct agcattaaaa
    20041 ttgttttatt attagaattt tgtttataaa ataattttcc tataaactca tcagatatgt
    20101 attttgtggt aatatcttct gatttaaata ttctctttaa ttcaacttct tttctttcaa
    20161 tagaagtttc aaatatcata ttcacaatta ttggtttatc aatagatata ttttctgcaa
    20221 aatttttacc ttcagtttta gatttttcca gcgaataaat taaccccata caattatcag
    20281 ccttataagt accttctata ggttcaacta aatctaaatc tacttctcct ttttcatttg
    20341 aacaaaacac tccataagat gaaaattctt ctcccttgca ccatggaaat tccattttca
    20401 cacttatttt aagtttagta tttggaatta agtccgaaac cataatctta agtctttcat
    20461 ccacaaatga ttctacattg tatacattta ctttcataat ctatttctcc ttataataat
    20521 tatttatgtt ttatataaaa cagctttatc taatgcaaca taaataaatt tttaaattaa
    20581 gacaccatat tgactatttc attttatcaa catattccat ctttgtcaat atattgtctt
    20641 ttttagtaat ttaaaattat gtagtctata tgaaatccag ttgatttttg gctaattaaa
    20701 gataggaaat gctattaggt ttaaaatata tctattcaaa ataaaaaacc actcatttta
    20761 agaatggttt ttaatataaa ctatttgtta ttaataagga tattttttta tttaaattta
    20821 tataatcgaa catctaatat ttaatgttta ataaaattat gcatttgcaa aagtatatat
    20881 ggcattaact cttgctacat ataaattctc atcactacat ccaatatatc tagcatattt
    20941 ttcaatcttt tcttttgcat tttcaacatc attttcatcg ctctccatta actcatttat
    21001 ataaatatcc attaatgacg ctttatattc tcttatatca tagcctaaaa attcagtcaa
    21061 tctctcaatt tccttactaa aatctccatc ttcttttacc aaaaattcgt atacatcttc
    21121 cctatatgga tttaaagtta ttatttgttt tactactttg cattcgtcag ccttcccaat
    21181 aaaaccatct ttataattat taaataaggc attagatttt tttatagatt cttcatcaat
    21241 ataagaatgt accgcagtta tacgattttc tataagggca tctacaacag cataatgaat
    21301 tttaaaacaa tcattgtata aataattgct cattttcttt attgtcgatt ctatttctaa
    21361 gaagctcgcg tggccatttt ttttattttt atttggtata ataaaagttt tattcaaatt
    21421 attaaaaagt ctcttaaaat ctaaatattt ttcacaataa acacttttaa aggtatcgat
    21481 atctatagtt ataattccaa aacttactat agtctcaatt cctttcttaa aagactcttc
    21541 tatatatttt tctcctaaac ttaaacctct atcagatatt tgctttagat tttgaaaact
    21601 atttaaacaa tctctttcaa agtttttaga tatttctaaa gcatataatt taaagatttt
    21661 ccttatctta ttataattat tttttgtatc atcaaatctg ataatagctc catttacatc
    21721 aaaagtaatc attgagtttt aacctcccca ttagtttcat caataaaata aatttaatat
    21781 aaactttata atcataatat taaacttatt tatactataa ttattaattt gatgataaaa
    21841 gctattttcc ttctaaataa aaaatttgtc taaagtttct aaaaaattta gacaaatctt
    21901 aggttattac tctttaaatt atttttaaat tattccaaat acgccaaata atattggtat
    21961 aaatatagct ggtaacaaat tggctacttt tatattcgtt aatttaagta catttagacc
    22021 aagtcctata attaataaac ttccagctgc tgtcatttct gtgactacag gatcacttaa
    22081 aaatccattt aaaaatgatg ctcccacaca tataatacct tcatacaaaa atacagatat
    22141 tgcagaaaac attacaccta tacctaaaga agcagtaaat ataattgaag ctattccatc
    22201 tataacagat tttacaaata aagtatcatg acttcctgta agaccacttt ctaatgaacc
    22261 aactactgcc atggctccta tacagaataa taaactagat gatataaaac cctctgctat
    22321 agaatctttt ttatttcctt tagaaaattt actttgtaaa aaagcaccca acttatttac
    22381 ccatttgtca atatctatta attctcctat cagagcacct acagctacgg atattattgt
    22441 cactaatgtg ttttttcctt ctagtgctcc tgatatacca atgtacaata cacataaagc
    22501 aattccattc attatagtat cgcttactct ttgaggtaat cctcctttta ttataagacc
    22561 tactatacat ccacctgcaa ttgctagact atttgctatt actccaaaca ttttttctcc
    22621 cctcgattag ctaattgaaa tttatcctat tattaaaacc taaacatcta tactttgtat
    22681 tggatatttt aaatattcca aaaattcttc aaaacctttt ctagatatat ttacagtttt
    22741 agtatttatg ttaggatgaa aatttaagta atcttcttta attacatctt tatctatgta
    22801 aagctcaact tttctttctg tatcatttat taatgaaaaa ggatttacac ttccaggaag
    22861 aagtttaagt acattgtata gtctttcagg tgaagcaaac gataatctag aacttcctat
    22921 cttatcttta agtgagttta aatcaacttg tttttctcct ttaactacaa taagataata
    22981 cttatttcct ttggcatttc ttaaaaataa atttttacat tgacacccct ttgttattcc
    23041 atctaaaatg actaattgct ctgctgtata tacagcttca tgctctacta catcatattc
    23101 aacatttaat ttatccaaaa tatcatatat tttagtttca ttcatgctag attcattttc
    23161 atcttgttct tttttattat ttaaatcact catacttttc tccttaaaca cttcatcata
    23221 atatcattgt gaggtattat tctactatag ctattgctct tactggagct ccatcagcat
    23281 cattatactt aaatggtgct gctataaata gaaatttttc tggaacattt tctaaatttg
    23341 taagattttc tatgattatt tttccttttt caaataaaat atgatgcact tcaaatactg
    23401 atgtgtcata tctatccact gatagcatat ctattcctat gccttttata ttagtattag
    23461 ctatatagtt tgcagcttct tttgttaatg taggataacc tacatagtac tgctttttat
    23521 cccaaaattt tgaccaacct gatttaaata ttataaaatc actatttttt atttcatctt
    23581 catatttttt tagatattct aattctatat tctcatttcc cttttcaagt tccaatacat
    23641 aagctttccc aacaaaattt tctatatcca acttatctag ggtctcacct ttagtataca
    23701 tatgtcttgg tgaatccata tgagttccat tgtgagaaaa tacactaatt aatgtttctt
    23761 gataaccatt ttcttcaata atagctactt tcttgatatc tggtctatta ggctctgcat
    23821 atacaggcat gtcattatgt gtcacatgag ttaaatcaaa aaccttcatc tttatatacc
    23881 ccctatgttt ttattttcta ttatatacct aaattcattt tatttctatc agattttatt
    23941 ccattatata ccatactact atatattttt tataaacctc aagggattta ccgaaaaatc
    24001 ttggaaagaa ttatcagtaa atataacatc ttcacccaaa aaacgtttat accttccttc
    24061 ttctttcttt aaagtaattc tctgtttttg tgaatgatta ttaaaaacca ttatcttaag
    24121 aggaggtttt tttctattag tctgcactct ttttaacatg tattttatgt gcatatcagc
    24181 ttcaggaaat gaatatccac aaaatattaa aaggtcagta tctcttaaag ttttttctgt
    24241 ttcattccaa acattactta aaaatatgtt tgacatattc ttaaaatatg ttggtggcac
    24301 tataataggt tctgttaact caccacactc taaacatttt gtctctgaac tattttcaat
    24361 aagcttcatg acaccacctt catgtggtgt aagagttaca ctattacaaa tggggcaata
    24421 aagccaattc aatgacccat gtatcttata taatttgatt aatggttctt ttggttttct
    24481 ccaatttaac tcctctttaa aatttgtaaa ctccacacca taatcaagca taattggcaa
    24541 atcattctta tctcttaatc cagtaactgt attgtctata tgtatatcat aatttgcact
    24601 aataaaagta gtatcaagaa gcaaatcatt ttccaaaaga ttttcaacta aaagtttatg
    24661 atatttatta tctgttctag gtgtattatg aattgcttca gccattagca gtattaaata
    24721 ttgtcttaaa aaacgtatac tatcacttct gttatttaga ttttctagtc caaaatttct
    24781 aaatgcttct tttctttgtt ctgctaagtc taaaagacct aaaacttctt caaaggtagg
    24841 aaaatttgca ttatctatat tatcttttac tatatcaata ttgaacatct gtttaaagaa
    24901 aatatacaat tctctattca ttttggtatt ataatttgtg ggatttagtt ttttaaaata
    24961 ttcgctaaaa agttcatttt gaataggtag attctctgct gctgaagctc ctgctcctaa
    25021 aaatattgct attttcatat agttcctcct aatataaata ttactcctat ttttatatcc
    25081 attaaatatc catatcattt attttatgat acaacaataa agctgtcttt tactagaaaa
    25141 aatcctatta caagacagcc ttatattata ttaaatcttt aataattcgt aaatagaaag
    25201 agcatatatt tgagtagctt ttataatatc ctctactatt aagtattcat tagcttggtg
    25261 ttctgtttct ggttttcctg gaaaaatagc tccaaatgca acacaattat ctaaagctct
    25321 tgcgtatgtt gctcctccag atgaaagtgg tgttccatca agaccagttt cttcttcata
    25381 tacttttcta agtgtcttaa caagaagagt atcttctgga acatagattg aatccaagaa
    25441 atcatattct tcataattta aattgtattt atctgtcatt ttctttaact cttttacaaa
    25501 atcatccttt ttgtatgtta ctggaatcct tacatctatt cctgcaaatt ctttttcgtt
    25561 atcaatagtt actctaccta tatttactgt tagtttacct gatacatcat ccttgcagtt
    25621 aggaattata ttgtttccat tagcatcttc accaataact tctgctaaaa acttaattat
    25681 attagaatct atacctatat tattaagagc tatacaaagt ctagccactg catttatacc
    25741 agtatcactt gctgctgaat ggacactctt tccaattata cagattttat taccttcaac
    25801 agtatactca aaatttaatt tattaagttc tttttttaat ttatcagagt attttccaat
    25861 atagattgct ttacctggaa ctgcatttaa agcctttcca actgacaact ctatatcact
    25921 tttgctatca caagtcaaat gaacttgtaa aagacctttc tctgcatttg ttattgggaa
    25981 tctagaatct ggagtaaatc catagtttgg tatttcttca ttattttctt tatatttatt
    26041 tatacatctc caaagatttt cttcatcagc cccaaaaatg aatcttatcc tcttattaaa
    26101 gtctacattt aaatccataa gagctttcac tgcataaatt gctgatattg taggtccttt
    26161 atcatcttgt gttcctcttc catacaattt accatcttct aaaacagctt caaatggagg
    26221 gtaattccag ctttctaaat caccttctgg aaccacatca acgtgaccaa gtatacctat
    26281 cattttttca ccttgtccta tttctgcata tccataatat ccatctttgt atactgtctt
    26341 aaatcctaaa gatttacata aatctaatat acctcttaaa gctttatcta cattttcacc
    26401 aaatgggcaa ttttcagttg cttcagatat aacactaggt atttttacac tttcttgtat
    26461 tgaagaaatc atttcatctt gtagagaatt tactttttct ttaatttgct ctttcatatt
    26521 atcacccttc aattttcatc ataatatact aataaatatt ttgacctttt aaaaaaaaaa
    26581 tatgcttatt ttttcagttt ttttataaat tcaatcgctt ttaaagtccc catttttgaa
    26641 tggtcaaatg taagtccacc ttggaaataa acattataag gaggtcttat tggagcatct
    26701 gcacttaatt ctatagaaga accttgtata aatgctcctg ctgccattat gacttcactt
    26761 tcgtatccag gcatgtccca aggaacaggt tttacataag aatcgactgg tgcagcttct
    26821 tgtatacctt cacaaaaact tattacttca tcagcattat taagtctaat acattgaata
    26881 atatcacttc ttaagtcatc atattttggt aatacatcat atcctaattt ttcaaaagct
    26941 cttgagcaaa agatagctcc cattacagcc tgagatacta tataaggcgc caagaaaaaa
    27001 ccctgaagta catttctagt tgttccaaaa gtaagaccac attcttttcc tattccagga
    27061 gaagtcattc tataagatat aagctcaatc aaatcttttc taccagctat atatccacct
    27121 gtcaatgcaa gcccaccacc aggatttttt attaaagagc cagccataac atctgctcca
    27181 acatcagtag gctctttggt atctaaaaac tcaccataac aattatcaac cattactata
    27241 gcttctggtt taacagactt tattacttct atagcttctt ttatatcact aattgaaagt
    27301 gattttctcc aagaatatcc ttttgacctt tgtatcataa cgagtttagt tctatcattt
    27361 attttgtttt taattccttc taaatctaag tttccatcct ctaaaaaatc tacatcatca
    27421 tatgtaacac catactcttt caatgaacct ttttcttctc ttatgcctat aactccctct
    27481 aaagtatcat atggtctacc agtaacagat aaaatttcat ctcctggtct aactatacct
    27541 tgtatacata aagtaagtgc atgtgtacca tttacaatta ttggtcttac aagagcatct
    27601 tctgtattaa atactttaga ataaatttcc tctatttttt cacgaccaat atcattatat
    27661 ccatatcctg tagtccagtt aaagtgcata tcacttagtt tagattcttg catagctttt
    27721 aaaactttat attgattata ttctcttatt tcttttattt cttcaaactt atcttttatt
    27781 tcttccatta tttcttgcga tagtttaaaa gtatcatcat ctattccata gtagtctttt
    27841 aataattctt ttgtctcatt aagcatttta tcacctgtct ctttattatt ttatttaaac
    27901 atgtaaagga gactatttta ctaaaacaaa taaattatag tttataagtt agtataagtc
    27961 tcctctcaat catcttaaat taaattaatt atctatctgt tgttattatt attgttgttt
    28021 tggttttgat ttgttagatt aatatacttt ccaggttgta tagttgatac agcatgttta
    28081 taaatcatgt tttgttgtct attatcccct tctattaata ttatataact atcaaacccc
    28141 tttacaagcc ctttaacttg cactccatta actaaatata tagtaacagg tatcctttct
    28201 ttccttgcat tatttaaaaa caaatcttgt aaatttaaaa ctgtattttt cattagattt
    28261 gtaccctccc aagattaaat tgaacttcta aaatattcct accttatatt ctatataagt
    28321 tatgacaaat tttcaatatt aagttgtata cttaaaaatt tatatattat tttatagaat
    28381 ctttaatata taagattatt tcatttttta attcgtctat attttcatat tggtctaaat
    28441 caaaccattt tgctgtttta tatcttttaa accatgttat ctgacgtttt gcataccttc
    28501 tagaatctct tttaattatt tcaatagctt cttcgtatgt atattctcca tccagatact
    28561 ttaatatctc tttataacct ataccttgca ttgatatcat atctttttta aatcccatac
    28621 ttaaaagttt ttttacctct tcaaccaatc catttttaag cataatatca actctcatat
    28681 ttattctttg atacaaatgt tctctatctc tatttagaac tattattatt ggttgatatt
    28741 cttcattaaa ttttaaatca cttgaaaaat cattcatttt cttaccactt agacaaactt
    28801 caagagctct tatgaccctt ttagtattgt ttttatggat tctattagca gattcttcat
    28861 caagttcttt taacttatta tgcatgtaat ctattccctt ttcagcaagt tgtttttgaa
    28921 gttcttctct taattcatta ttggcatcag attgtgcaaa atccatatta tatattaaag
    28981 agtttaaata aagtcctgtg cctccagtta ctaaaacaca tttttccttt ttatttattt
    29041 catgtatata tttttttgct ctttgttgaa actctgaaac tgaaaatgga tagtcaggct
    29101 taacttcatc tataaggtaa tgcttcactc cttgcatctc ttcctctgta acttttgcac
    29161 ttccaatatc catatattca tatatttgca tagaatcagc tgaaattatc tctgcattca
    29221 tatcttttgc taattttatt gacaaatctg tttttccaac agcagttgga cctgtaagta
    29281 ttataagtgg tatttttttc ataacattcc tttccatata ttttaaatat ccaaatattt
    29341 tacataattc ttttaaacat tttttctatt tctgtcttag atatttcgac cattataggt
    29401 cttccatgag gacatgtaaa tggattctca cacttttcta gctgttccaa taaacttttt
    29461 atttcaatat cgtatatttt atcatttgct tttatagcag acctacatgc catagatgca
    29521 aatctctctc cttttaaatc ataattactt gtaatttctt ctatattatc aattatttga
    29581 agtataaatt tctcggtttc aggtactcca aatatagtag gaacacatct taccattata
    29641 tgattattgc caaaaatttc tagctcaaaa ccaaatttca taaataactc caagttattt
    29701 tcaatttgaa gcatatctac atttgatact tcaataacca ctgggtctaa aagtatttgc
    29761 atatttatat cttgtctata gaacttctcc atatatcttt catatagtat tctttcatgt
    29821 gcagcatgtt ggtccaacaa atacatagaa tcgtctttgc tcaaaattat ataagtatta
    29881 aatacaactc caattacaga atatccgtat aaagaaaact tgcgttttga actacacaag
    29941 tattcttctt cactgtcctt aatactatct cctaagtaat aatttccttc atttttaatt
    30001 ccatcaactt gaaactcttc ttgtatatta tcatttgcac tatcttcact tagataatta
    30061 atgtttttta catcatcttc tacacttgca tttaggactt cacttactga ttgaaattca
    30121 tttattggtt tttcacttga taaagtaaca acttcaatga cttcatcctt acctttagta
    30181 atattactat ttttaggagt agattctaat aaatcattat ttcttaattt ataatctgta
    30241 cttttttctc tactgttaat agcgattcta ggttgtgttt ttttatcact ataagtagca
    30301 tattttccaa taagatttga gtgtattaat ttaaccttta aaaaatctct aagttctata
    30361 tacacttctt gttctttttc aaatttaatt tcaagtttat tggggtgtat atttacatct
    30421 atacatgatg ggtctacttc tatatttaag aagcacactg catgtttacc tattggaatt
    30481 atagacttat aactttctgt tattgcatct atgattattt tactttttac aaatctttta
    30541 tttatataga tatgttgtaa gtttttattt gaacggtata tattgttatt acctatatat
    30601 ccattcattt taaagtgatt gcacttaaac tctacatcta ttatattttc cgttatttct
    30661 tttccatata tacttctaat agtgtttaca agctttccat cccctggagt atttagcatc
    30721 tgtttattgt tatttgtata tttaaattga atgtttggat tacctattgc aagtttattt
    30781 atcaaatcac ttatatttat agtttctgca tgagtagatt ttaaaaattt ctgtcttgct
    30841 ggtgtattaa agaaaatatc ttttataatg atggtagttc cattagtaga acctattggt
    30901 tctttcgata ttatttttcc accttcaaca tatattttag ttcctattat ttcatcttta
    30961 gttttagttg tcatttctaa ttttgataca gctgaaatag atgccaatgc ttctcctcta
    31021 aaaccaagag agtataaatc atacaaatca tcaatttttt taattttact agtagcatgt
    31081 ctcaaaaatg atttttcaac ttcacttgaa ggtattccta ttccattatc tgtaatctta
    31141 attagacttt ttcctccatc aattatatct atggaaattt tatttgcacc tgcatcaatg
    31201 gagttttcaa taagttcttt tactacagaa gaaggtcttt ctacaacttc acctgctgct
    31261 atcttattta tagtcaaatc atctaggatg ttaattatat ttttcatttt tacacctcta
    31321 agattttatt tcttttgctt ttctttgaag attataaaga gagtttatag catctaatgg
    31381 agtcatattt aaaatatcca gatttaaaat ttcttctgat agtatatctc tatttacact
    31441 atcaaaagag atttgagtta aggctacttc ttttacagaa tccacttgat taattttctc
    31501 tttatcatca ttttgcttta ttaaagcaac ttcatcattt aatgctttaa atttagaatt
    31561 taatttatca taatcctttt ttatatgttt gtagtctttt actataagtt catgttctat
    31621 ttttagagat tcatatttat tcttaaaatt actttgattt accttaacta attcttcgtc
    31681 caaattacta ttaattatat tattgttttc tttatctcca tttattgcaa cactgttgta
    31741 aacatgattt ttttccaagt ctttaagtat atattttgct ctttctatga cttcgtctgg
    31801 taatttagct aatttagcaa catatattcc ataactcttg tctgctccct gaggaattat
    31861 ttttcttaaa aatattattc cttccccatc ttctttgact gctattgaat aatttttaac
    31921 ctctttaaac tcttcttcta aatcagtaag ttcatgataa tgtgttgcaa ataatgtctt
    31981 acatctaata tttttttgaa tatattccac tattgaccat gctaaactta taccatcata
    32041 ggtactagtt ccacgaccta tttcatctaa tataactaaa cttctctctg ttgcattttt
    32101 taatataagg gatacttcgt tcatctctac cataaaagta gattgacctt gagataaatc
    32161 gtcactagct ccaactcttg taaatattct atctaatatt ggaatatcag cagactctgc
    32221 tggtacaaat gagcctatat gtgccataag agctattata gcagtttgtc tcatatatgt
    32281 tgatttacct gacatattag gaccagttat tatgttaata atgttttctc cacgatttaa
    32341 ataagtatca tttggaacga aattttcctc tcctactata ttttcgacaa caggatgtct
    32401 accatttctt atatcaagtt tattattttc atttattgct ggttttacat agttatttat
    32461 atgtgcaact gttgcaaggg acacaaaaac atctatatta gctatagtct tagccacttt
    32521 ttgtattcta tctatgtttt tatatattgt atctcttatc tctacaaata tctcgtattc
    32581 taaagattta atcttttcct ctgcatgtag tatcttttct tctatttcct ttaattctgg
    32641 agttatatat ctttctgcat tactaagtgt ttgctttctt atatatgtct catctagctt
    32701 tgcctgttta aagttagctt ttgttatttc tatataatat ccaaaaactt tattaaagcc
    32761 tatttttaat gatttaactc ctgttttttc tctttccctg ttttctattt cctttacaag
    32821 aaaggctcca ttcttagaaa tctctcttag ttccttaagt tcatcactaa aatctgattt
    32881 aattatgttt ccatctttta tggttatcgt aggttcttct agaatagctt catctattaa
    32941 attgtatata tcatctaatt tatccatttc tgaaacatac tcttttagga tttttgcatt
    33001 tgataaattt atagtatctt ttaaattagg taacttttct atcgaatttt ttaagtgaat
    33061 taactctttt ggtgttactc tctcaaatgc tatctttcca catattcttt ctatatcgta
    33121 tatattttta agtatatcat ttaggtcttc tcttaatata aagtcatctt ttatttcttc
    33181 tattacatct aatctatttt caattttaga tttatttatc aaaggttctt ctacatattt
    33241 tcttaaaagt ctacctccca ttgctgtaga agttttatca agtacgtgta ataatgaacc
    33301 ttttttctta ttccctctta tagtttgagt aagttctaaa ttagttctag taaacatatc
    33361 tagaaccata tattctgatg aattgtatat atttatatta ttaatgttag atgttatttg
    33421 tttttgagta ttgtatatat aattcagaag aattgataag cttgacttta ttagaccttt
    33481 atcatcaaac tttagttttt gtagataaac atctggaaaa tattctttta atatatttat
    33541 atccaaatag ttatcactaa aactttcatt tatgtatata ttacttacag tagctatatc
    33601 tctaagattt tctataaagt ctaaatcatt tataattatt tcagttggat ggatttttgc
    33661 aatttcttca attaccttat cttcatttaa acatgttgca ttagtttctc ctgtacttat
    33721 atcaacataa gttagaccta tattagtacc atccttatac aaagataata aataattatt
    33781 ctttttattt tcaagtaaat ttccatctaa aactgtacca ggagtgatga ctcttataac
    33841 ctctcttcta acaattcctt ttgctgtaga tgggtcttcc atttgttcac ctattgctac
    33901 tttatatcca ttttcaacta attttgatat atatgaattg gctgagtgga aaggaacacc
    33961 acacatagga gcacgttctt ctaaaccaca agcttttcct gtcaatgcta tttcaagagc
    34021 ttttgaagct actaatgcat cttcaaaaaa catttcataa aaatctccaa gtctaaaaaa
    34081 cagtatacag tctttatatc tattttttac ttcaagatac tgtttcatca taggagttaa
    34141 tttattcata tctatttgca ttatcaaacc tccttctttt ctaattaaat attatatcat
    34201 agtagatgat tattattaac acaatatata aaattttgac atataactaa aaacaatcca
    34261 aaatgtatac tcacattttg gattgctaag tttaatgctt attaaataaa aatatttttt
    34321 ttacaataaa gatattattt cttttttaag tttaatgata ttttcaaggt tatcttcatt
    34381 taactttcta ctatctataa caaattcttt ctttactatt gatggttttt ttgaaataac
    34441 ataaattctg tttgatagca ttatagcttc gtcaatatca tgagttataa gaagtattgt
    34501 tgaatttact tttttcttaa catctaaaag ccatttttgc atggatgttt tagttaatga
    34561 atcaagtgcc ccaaaaggct catctaaaag cattatgtca ttagaattta taaaagttct
    34621 caagaagtta gctctctgtc tcattcctcc agaaagttct gaaggatatt tatcttcata
    34681 tccgcttaat ccaaacacct caaaataagg ttttaccatt gacctagctt tactcttttt
    34741 ttcttttttt aaaattagtg gtagtgacac attatctatt atagttttat atggcaagag
    34801 taaatctttt tgatacatat aactatactt accatttata ttcactttgc cactatcata
    34861 atctgtaagt ttagttataa tattaaaaat agtacttttt ccacatccac ttggccctaa
    34921 tatagaaaca aactcacctt cataaacatc aatacttata tcttttaaaa cttcaatatc
    34981 tttataagtt tttgatacat tttctataga tacttttact tttttattgt ggtaaaaatt
    35041 catttgtgta agcatcactt gccttcatat ccttatctat taatttatat tcttttaaga
    35101 atgatgtata gttgttccat acactatctt tcatttctcc ccatcgtggt gcatcatctt
    35161 tgtacttgct tgctaaatat tcttgactct ttaaagctag tttttcatct acttcaggtg
    35221 catgttttac taaaattttt gctgattctt ctggattttt tattgcatat tcataacctt
    35281 ttgttgtagc ttttaagaat tttttagcaa gctctggatt atctttaagc acagtttcat
    35341 tagaaattat aagtggtgta taataatcca atctctcatc taaatctttt actggtataa
    35401 agtttaagtc atatccaatt aaatcagctt taactgcatc ccaaccttca aatatccatg
    35461 caaaatctac agttttcata gctgcaaaga aatcatcttg accagtatta actatcttta
    35521 acttattaaa atcagctcca tttttcttca taactgcttt aaaaacagct tcttctgatg
    35581 gagagcccca accaccataa gtttttcctt caaaatcttt agctgttgtt atattctttt
    35641 cttttggtga tgcaaaccca gaagtattat gttgtataac agttgctaca gcttttattg
    35701 gaagtggatc ttcactagtc tttgcataag taacttgttc ttgatagctt ataccaaagt
    35761 cagcttttcc tgttgctact aaagtttctg ctccactttc aggtggttgt actatttcaa
    35821 catccaaacc ttcttcttta tagtaaccct tatcaagtgc tacaaataat ccagtatgat
    35881 ttgtatttgg tgtccaatca agcaccatag ttactttttt agaagaagta tctttatcat
    35941 tgtttttgtc tttattgtta tttgaagaac atccagttat tgttgccaat gtaaaaacac
    36001 ttactaaacc taatattcct aactttttaa aattcataat tgcctccctc aaataccttt
    36061 aatctattaa tctatgtctt ataacaactt tttttacagc ctgtacaatt cctacaaaca
    36121 ttaaactaaa tataactact aatatagtag atgcaaatac tttatcaagt gcatatgcac
    36181 tttttgacct aagcatataa acaccaagtc ctttcgttcc acctagccat tctgcaacag
    36241 ttgctgccat tacagcatat gttgcagata ttttaagtcc agaaaaaaat ttatccattg
    36301 ccataggaaa tttaaggtga atgaatgtat taactttatt tgagtccata gtcttaaata
    36361 aatttaaata atctttatca atattctcaa tgccatctac aaaacttatt aatataggaa
    36421 aaaaacaagt aagcattacc atcaatactt ttggcattgt tccaaatcca aaccatatca
    36481 taaagagtgg tgctataatt attgtaggta tcatctgtgt aaccaacata ataggataaa
    36541 gacatttttt tattattgat acaaaatcca tcaatattcc aattaccaat gatattataa
    36601 ttgcgactat aaaaccaagt attgcttctc ctatagtaac cacagcatgc atggataaat
    36661 tttgataatc tttaaaaaac acattaatta tatctactgg tgtgggtagt atatactgag
    36721 gaacttctaa aactcctacc atagattgcc aaagaataag tataaacaaa aatgttgcta
    36781 ttggatatat actatctttg actttatcta tgatttctaa gtttttcatc tatagtcaga
    36841 cctccagctt tttcatctac tctagctact gttatgactc tttcacatcc aagattaaaa
    36901 gggattttat gtaccttttt taataattca aaaacttcat caaaatcacc ttcaacagta
    36961 gtgctcattg ctcctatttc acatttaaga ccactttttt caatttcagc aatacaagca
    37021 tctactactt tatacatctc ttcttcacct ttgtaaggtc ttagtggcat tactgctatg
    37081 tctgcgatta ccatttaaat cactccttta aaaataatta atacctacta ggtatatttt
    37141 gttttttatt aaaaaatttt attactaaaa agatattata tttaaataaa agaaaagtct
    37201 tatccaaaat aggataagac ttatttttat cttaactggt ctccctacac tggcattatc
    37261 caaacaggtt caaagggtcg agataaaatc tcctctcagc acattagctc cccgaaatat
    37321 attatatctt ttctacttga ttatactaca cttatcatat tttaacaaat tttttattta
    37381 tattagatat tttatccgtt caaaaatatc taatataaat tgtacattat tacaccaaat
    37441 aaattatctt aaaatggtat tttatcaaca tcttccaaaa ctagattaac tgaattttct
    37501 agtttttatt ttgctatttc aagcatattt ggatgtatat caattccata caaatattgt
    37561 gctaaatttc tgttttcact catctaattt gcaatcgtta cagattacag attagaaaca
    37621 gtttttagac tctacttatc tttatctaca aaaaatcttt caataaattc attaataata
    37681 ttcagtaatc taaaaataaa cctctatctg gatttttaag atacaaacct tttaggaagt
    37741 atcttttgtg ataatataaa aattactcgt cattatcatc aaaatcctca gcaaccaaca
    37801 ttttatataa gaatcaaact ctataatata attattttat ccaatttatt tttgagaaat
    37861 aaaatatttt tttaattttt aaatttttta atatgcacct tgaaaaaaga aacgttttcc
    37921 tatattatgg taatagtaga ataaaactaa ataggcaaaa ctagagaaat ttagtgacgc
    37981 aaagctatag ggactaagac ttatgaaatg agttatgtca gccagttgcc aaagagatat
    38041 tttctttttg tttttatgaa tgttttttag ggggatatat gatatatgtt tatggataaa
    38101 atggatagat gtacacatat actaactgca tatatatgca gttcacgcga ttactgcaat
    38161 tttatagata cacaattaaa tgattttata ctagaatatg gagagaatgt ggtagaatct
    38221 tgtttgcatc aagtgatggt attggtaagc agatataatt aaagaaattt tattttctag
    38281 aaaacccttt ttagttttat ctacgtttta taattcatta aagaactaat taaaataagc
    38341 ttcattatat atttttcatg aagtaaacag ttaagtttat ctcatatact gtttacccca
    38401 attacataat tctaataata tagattccaa tgatttacca cgtttagtag acaaatattc
    38461 aacttttgga ggaatagtcg gataagaaat cctcttaata agtccatctc tttcaagata
    38521 ctttaattct tgtgacagta tcttatgact tatatgaaca acttcttttt ttaattgact
    38581 gtaacgtatt ggctcttgtt ttaaaatatg ccataaaata attgccctcc atttacttcc
    38641 tatcacagtc atggtaaaac caattgaaca attaaaatct ttttgtcttt cttcaatatt
    38701 tggaaattct tcaaaattat tatctatatc catctcaatc ctctctttca aaatagtaag
    38761 tatctaacta aaaagtgcat tcttgtttag cgtactaatt cgtaatataa tcttgattaa
    38821 aaaatagcta tgcacactcg tgactttagt catgggaggt tcagtgtagc atagagcctt
    38881 acataatact acttttttag atgtatatgt ttaaatttta atatagacat atgttatttt
    38941 attaatttta tttaaacaga taataataaa taataattta tctcaagttt tctatgtaga
    39001 taaactaatc taatgtttag aaaggattat ataatatgaa taaaaaattt cgtctttatc
    39061 aagttgactc attacaaaag aaaaatttac aggtaatcca gctggtgtaa ttacaaatgc
    39121 tgatggctta tctgaatcac aaatgcaaaa aatagcaaga gaattaaata attcagaaac
    39181 tgcttttatt ttcaataact tggctaaaaa tcatcaagaa aattatgatg tacatatcag
    39241 attttttaca ccaactaatg aggttcctat atgtggtcat gctactattg ctgcccatta
    39301 tgttagagca atagaaaacc aattcaataa caaaacagta tttcaaaaaa ctggtgctgg
    39361 aatattacca gttgatatta taaaaaaaga taatgattat gaaataatta tgacacaagg
    39421 aaaaattgaa gtatctccac cattacaaca aacctatcaa aaaagattac ttaatgcatt
    39481 tggtatttaa aggaagatat tcgtacagat tgtcctattg ccatatcatc tacaggacat
    39541 tcaaaagtta tgattggaat aaaggaatta tcaacattaa atagtttatc tccaaattta
    39601 tatgaattat cgaaaataag tcaagaaata aaatgtaatg gatattatat ttttacatta
    39661 cataataaag aaactctaca agttcatgga agaatgtttg ctcctgcaat tggtatttca
    39721 gaagaccctg ttacaggaaa tgctaatgga cccttaggtg cgtaccttgt acattataaa
    39781 gtaataccta cacccaacac agagtttata tttgaagcag ttcaaggaga agcaataaaa
    39841 cgcaaaggca agatgttagt aaaagtaatt attttagata ataagccagt tgaagtaaaa
    39901 ataattggaa aagctgtaat tgcattctca acaaacatag aaatctaatt atagattcct
    39961 tctaagtaaa tttttgaact ttttaatact aatttaataa caaactaatt tatatacaat
    40021 caaattaatt tttttattat ttgttaatat atatttatca ttatattata taataatata
    40081 gatagttact atatcttata attagataaa tcataattat atattattgt taaaactcaa
    40141 ttatataatt tttaataata ttattttagg aggtaaaaat gataaacgat attaaaaata
    40201 aattcaaaaa ttacaaacca tatataaatg gatacaagaa tatgaagaga gcatctgttt
    40261 taattccaat agtagaaata aataacacac actatatatt atttgaagtt cgctcaaaaa
    40321 atttgaagca tcaacctagc gaaatttctt ttccaggtgg taaaatagaa tcaggtgaga
    40381 ctccatatga agctgttatt agagaaactt gtgaggaact tggaactttt agtgacaata
    40441 tagaagtaat atcaagtctt gacctcctta taacaccagt aaagtttatc atacatccat
    40501 acttaggata tataaaaaat attaataatt taaatataaa caaggatgaa gttgaccata
    40561 cttttttggt tcctataaaa tatcttttag agaatcctcc aaatacttat agtaatactg
    40621 taaaagtttt tccagatgaa aatctaccat atggttcaat tccaaaccaa aaagattata
    40681 aatttgaaag tggaagttat cctattctgt tttataaata taaagattat gtaatttggg
    40741 gaatgacagc aaaaatacta gaaaactttt taaatttttt atcagaataa cactcataat
    40801 aaattatcaa aatttttaca taagaaattt ataaaagttt ctaaatttaa caattctaaa
    40861 atatcaataa ctatattttg tagcactttt ttattttatt attgtttgaa tatttgatgg
    40921 ttttcaatgc aatttcaaca taaatactat atattagtgt atactgttga tgaattaaag
    40981 tatgataatc tatttaataa agtatgaagt aaatgatttt aatgtgcctt tatggtaaaa
    41041 ttactaataa gtaataaaat taattaaaat atatggaggt ccttataatg tttgctgtag
    41101 gatttgttgt tataattgca cttgcctttt tcattttaag tgtactatta tttaatggaa
    41161 aagccagtat gctactagca ggttataact ctatgagtaa gaaagaaaaa gcacgatacg
    41221 ataaaaaaaa attatgtaga agttctagca ttgttacttt tattgtctct ataatgctat
    41281 ttattatggc gtttttggga tatagaatag agagtggtca aatggacgaa aaaaaaatgg
    41341 ttcccttttc tataatattt ataatagtca tactttccag tgtatttttt aatatcctct
    41401 actctaacaa aaaatgtaaa aaataaatag ttgtaagttg agcagttaat tataaaagat
    41461 tgactgcttt ttcatgtata ttgactactc ttattaaata ttttaacatt taaaaatcta
    41521 tgtaaaaata atgaatatag tacaaacttc taataatgat tttacctttg tggttacagt
    41581 ccactatata taatttaata tgataacagg gaattattaa tgacaactaa gtaaactttt
    41641 ataaaatata ataaaacaaa aatagatgta caatgaaatt atatcttata tcaaatttat
    41701 ttttattaat agcaaaaact tacattagca taacatatga caaattcgct taaaataaaa
    41761 atttttaata taatttgttc tatagtacat ctattttgat tagtttacat aattttatta
    41821 ttttgtacaa tattaattat ttactaatat cccatttaat gaaaaagttc taggttcagt
    41881 aattttgacc ataactaatt taccaattaa atcatcattt ccaccttcga aatttacgag
    41941 tttattttgt ctagttctac cagcaaactt attttcatta tttttacttc ttccttcaac
    42001 tagaacttca actattctat ctttatatcc atcatttatt tctgcagaaa tcctatttac
    42061 agcttctaac accctattaa atctatcatg ctttatatct tctggtattt gattttccat
    42121 tttagcagca ggagttccct gtcttttaga ataaataaat gtaaaagctg aatcatatct
    42181 aactttttca accacatcta aagtgtccaa taaatcttct tctgtttctc ctgggaaacc
    42241 aatcattaag tctgtagaaa aagcaatacc tggaacttcc tttttagctt tttctattat
    42301 ttctaaataa tattcctttg tataatgtct attcattttt ttcaaaaggc tactgcttcc
    42361 gcattgtatt ggtagatgta aaaactcaca caccttatca caatctctaa ttgcgtatat
    42421 tacttcatca gatatatctt ttggatgaga tgtcataaat cgaacccttt caattccttc
    42481 tatatcattc acttttctta aaagttctga gaatgaaact ggattttcaa gtgtcttacc
    42541 ataagaatct acattttgtc caagtaaagt gatttctttc gttccatttg caacaagctc
    42601 ttttatctcg ttaattatat cttcaggagt tctacttctt tctcttcctc ttgtgtatgg
    42661 gactatacaa tatgtgcaga aattattgca tccatacatt atatttacaa atgcttttaa
    42721 ttcaaatttt ctattacttc taagaccttc tattacttct ccatccacat cccatacatc
    42781 cactaacatt ttgtcagaat ttattgattc tgtaagtaat tgcggaaatt tatatagatt
    42841 atgtgttcca aatataaggt ctacatgttt atattttttt cttaattcct ctacaacatg
    42901 tggttgttgc atcatacatc cacatacagc tattttcata tctggatttt ttccttttag
    42961 atgttttaat tgtcctaagt taccatatac ttttagctct gcattttctc taactgcaca
    43021 ggtgttatat attattaaat cactttcttc aaccatcatt gacatttggt atcccatctc
    43081 ttctaacatt gaacataatt tttctgaatc atgttcattc atttgacacc caaaggtttg
    43141 agtaaacacg agttttctct ttccagttct gttgaagtat tcttcatttt gtctgtgtat
    43201 ttgttctata tatttatctt gttcttgtat tttctctata ggtattgtta cttgttttct
    43261 tttgctcacg tctattcctc ctagttaatt tcttatatta cacataacct taattatatc
    43321 aaataagaaa aatcttttaa agatattatt att
//
LOCUS       DAFAZV010000033        43234 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFAZV010000033 DAFAZV010000000
VERSION     DAFAZV010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43234
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.033"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            272..1390
                     /locus_tag="KOU88_002513"
     CDS             272..1390
                     /locus_tag="KOU88_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3212384.1"
                     /translation="MIAVKKAYKFRLYPNKKQQELINKTFGCCRFVYNKYLAKRIDVY
                     KNNKETFTYKQCSSDLTNLKKELKWLKEPDKFSLQNALKDLDNAYKKFFKEKAGFPKF
                     KSKKINRFSYKTNFTNGNIMYCGQHIKLPKLGMVKVRDKQVPKGRILNATISKEPSGR
                     YYVSLCCTDVDIEAFENTNNQIGLDLGIKEFCISSCGEFIENPKYLKKSLNKLVKLQS
                     ELSRKTIGSLNRNKARLKVARLQEHIANQRKDFLQKLSTKLIKKNDIICIEDLQVKNM
                     IKNHKLSRSISDVSWSEFIRQLEYKANWYGRQIVKVGKFFASSQICNKCGYKNEEVKD
                     LNIREWICPSCNETHDRDINASRNILKEGLRLITIQNK"
     gene            1517..2686
                     /locus_tag="KOU88_002514"
     CDS             1517..2686
                     /locus_tag="KOU88_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBK3212385.1"
                     /translation="MNELCKDEVVEFCNRIKGKVESVAISGVFAPVNKQQEEEVAKWV
                     REILGDIPISLSNEIGNIGILERENGAILNSALSQVGKAVSLGFEKALKDLGIDAQIY
                     FSQNDGTLMNLEYTMKYPIFTIGCGITNSIRGASFLSKVKNAIVLDVGGTTSDLGVLY
                     NGFPRESSIPVTIGGVHTNFRMPDVLTIGLAGGTCVKGEKDNIKIGPESVGYRITEDA
                     IIFGGDTLTLSDVVTKLDMAFEDRKSNVENLDKEYCNEVYKKVILKLEDAVDQMKTSQ
                     DDVELVLTGGGSIIVPEKLKGISNVIRPPHYTAANAIGAALGQISGDVEKVYSLDKMS
                     REDAIEDAKKEAVNKALKAGAKEDTIEVLNIEDVPLAYLPGNALLIKVKVVGDLI"
     gene            complement(2849..3391)
                     /locus_tag="KOU88_002515"
     CDS             complement(2849..3391)
                     /locus_tag="KOU88_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HBK3212386.1"
                     /translation="MKSYIALLRGINISGKNKIIMSELKASFVELGYSEVSTYLNSGN
                     VVFLSDVDDSKVISNTIRLMIKKQFELEIPVFIISQEELKDILNNAPNWWGDNNKEIY
                     DNLIFMFPDLSYDEFYDEVGNPKEEYEKVYHYKNAIFWSFSRKDYKKTNWWSKTASSN
                     VSDKITIRTANTVRKIVGMR"
     gene            complement(3539..3823)
                     /locus_tag="KOU88_002516"
     CDS             complement(3539..3823)
                     /locus_tag="KOU88_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK3212387.1"
                     /translation="MAKNTKQTTVHIDETLLKEVKRIGINENKSISQIINESIIDYIL
                     VYRENEDKEKNEHDKNLNETINEFKKEEEKRMQAKSAARAIAEAKKRVLY"
     gene            complement(3886..4650)
                     /locus_tag="KOU88_002517"
     CDS             complement(3886..4650)
                     /locus_tag="KOU88_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBK3212388.1"
                     /translation="MNNYLKFATYQLIGFTSSIPRLIKIKKNPDKFSLKEKFEFMQKQ
                     AKKSLDIVNIELNIIGKETLPKEPLLFVVNHSSMLDSFILTASVERPIGCVIADEPVW
                     RNIPIFKEWAKLLRCVYVNRKNNREGIKSIAQASQNILTGQSMAVFPEGDLTWIKEPN
                     SLVSEFRSGALKIAYKAKCPIVPLVIKNSKDTYEGYQPIGKINSVPVEVEFLEPIYDH
                     IENPRLKSSVLGENIKNKMINTIENFRKSNKTFKEF"
     gene            complement(4932..5198)
                     /locus_tag="KOU88_002518"
     CDS             complement(4932..5198)
                     /locus_tag="KOU88_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBK3212389.1"
                     /translation="MIESRCGILCYECGYKEKVNCKGCTEIEKPFWGEQCPVKSCCED
                     KNLTHCGLCDTFPCEMLNQFAYDKEQGDDGKRISQCKKWAVLAL"
     gene            complement(5240..6049)
                     /locus_tag="KOU88_002519"
     CDS             complement(5240..6049)
                     /locus_tag="KOU88_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212390.1"
                     /translation="MNKIINNILNTCKQYTYILPHKLLRQYIAHYTISIPDTSIKENL
                     TLIPDASGCMIFKFDKKGIESAFWGATTKTTIVKNDIENVLFRVFVEFRPGGVYYLTG
                     LSQRESTDLKISLEDFNTLFSLEVNSIFERTSTIKELVEQLDMLFLSYLLKSNIVDMT
                     IPILENARKQNSIMSVKNISQISCYSERHLNRIFNNSLGMSVKSYLRLLRINLVLQEI
                     QNNKIPFATLAQDIGYYDQSHFINDFKSICGVNPTTYIKNLSDFYNEKYKF"
     gene            6362..6643
                     /locus_tag="KOU88_002520"
     CDS             6362..6643
                     /locus_tag="KOU88_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212391.1"
                     /translation="MASKQIPRNNLEKFLRIRVLSHTGDKIHIKLPVNFAKRMIENNA
                     LDLFNGKDDVVDGKKVTEILVKAFDYDLTGEVVHLERKNGDIIKVSIVQ"
     gene            6907..7161
                     /locus_tag="KOU88_002521"
     CDS             6907..7161
                     /locus_tag="KOU88_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212392.1"
                     /translation="MENKDFKLTICIFAFVIGVVVLFCCIGLGEFSAEHIIQQNGGIM
                     DTDQYNIYLDQSISQYRNFGSILALLGGIGILFDKYIRKY"
     gene            7206..7529
                     /locus_tag="KOU88_002522"
     CDS             7206..7529
                     /locus_tag="KOU88_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212393.1"
                     /translation="MATEIFTVKITPLEAQKMIKENLDADLVFSDSYNLGDDKFILIT
                     TFEKYYARNNSDAGLIVVYENTTGKTVIKATSTGSAIGILKIDWGAGGNLLKRVKNIL
                     ADYII"
     gene            complement(8088..8282)
                     /locus_tag="KOU88_002523"
     CDS             complement(8088..8282)
                     /locus_tag="KOU88_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3212394.1"
                     /translation="MINYMVEIIYSEKISEVENMLKIENIQYEFTSRDGFIFFGFYDM
                     TDAYRFETLCSDEKIRFKRI"
     gene            complement(8656..10275)
                     /locus_tag="KOU88_002524"
     CDS             complement(8656..10275)
                     /locus_tag="KOU88_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBK3212395.1"
                     /translation="MNIVISLIGGLGLFLYGMSLMGEGLQKSAGDKLKKIIELLTSNV
                     VMGVLVGTVVTGIIQSSSATTVMVVGFVNAGIMNLSQAIGVIMGANIGTTVTAQLVSF
                     NLEGIAPIALGIGILFYLFTSNQKTKHLSEILIGFGILFTGMEFMKDAVAPLAEYKAF
                     TDALLYFSKNPVLGILAGFAITGIVQSSSASMGMLIALASQGILPLSSALPILYGDNI
                     GTCVTSLLSSVGASRNARRAAVMHLSFNVIGTIIFMLVLNKPISAIVTHFDPTDTARQ
                     IANAHTLFNLTNVIILLPFSKYIVKLANRLIPIKETESEIVNNTKYLDERMFSTPSIA
                     LGNTVQEVVRMGHKATNSLEHSIAGFLNKSNEDINKAFESEKVVNKLQKDILNYLLKL
                     SKEPLRDDERFRTDLLFNTVNDIERVSDHAENIAELAMSVKEMNISFSDSAIREIYEI
                     YNKTITNFKDALIVLDVKDFELANKVLEVENEVNYLEKTFRNSHMIRLNNGSCTIDAG
                     VLYLDLLTNLERISDHSTNIVKQVLKLKQKI"
     gene            complement(10584..10790)
                     /locus_tag="KOU88_002525"
     CDS             complement(10584..10790)
                     /locus_tag="KOU88_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212396.1"
                     /translation="MFKKKSGYTFTNFLNKVRVEKSKKYILKKDLSILDVAVLIGFNS
                     QNYYSIIFKKFNNFTPIEYKNIYN"
     gene            11095..11286
                     /locus_tag="KOU88_002526"
     CDS             11095..11286
                     /locus_tag="KOU88_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212397.1"
                     /translation="MERLMELIERKFLKDVELLELEDIENVIECKMTQPYNAHYNEYL
                     VKVKNGDEVEEYFVYLKHR"
     gene            complement(11375..12187)
                     /locus_tag="KOU88_002527"
     CDS             complement(11375..12187)
                     /locus_tag="KOU88_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mrp/NBP35 family ATP-binding protein"
                     /protein_id="HBK3212398.1"
                     /translation="MADCNSCPSKGNCNSQSNCSIENNPNNKFGKIIGVMSGKGGVGK
                     STVTALLANKLNKMGYKVGILDSDITGPSIPRLMGVKNVKAYSDGSYIYPVENSNNIK
                     VMSINLMIDDENEPVVWRGPLLGGVVKQFYTDVLWEELDYLLIDMPPGTGDVALTVMQ
                     SIPISGIVMVSVPQDLVSMIVSKAVNMAKKMNINVLGVIENMSYIQCPDCSKKIKLFE
                     GESTEKFLDDLDLELLGELPMTKEIIDITHNGVTEISDDLDSILTNVVEKIK"
     gene            12609..13760
                     /locus_tag="KOU88_002528"
     CDS             12609..13760
                     /locus_tag="KOU88_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004452985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3212399.1"
                     /translation="MELRPRSAKLEEFDKVIELINYVFRISRSHKPTMMEEFPLLLSK
                     NNIENMIIISEDDKVVSDVNYLIQDVSIQGNRLKVAAIGGVCTHPDYEKRGYSSKILD
                     KVEEKMFYDGVDIVIISGTRSLYSRRNCSLVKSFYKYTIKPEDVKIAYEIVEFDETNF
                     EKDNDLDKMIELYNQNSTRFIRTRDEFQKLLHAATIAWGPIGYKKVFIKENNNIIGYL
                     IIRTIKKEDSTVGEVAEIGLNSVNVENILKYVANKFGLEYLNYKVHVKNLKDQLKCNG
                     TKSLDYQQGTMKIINFTKLCDSLRSYFSQYVDFELLKYMEFKQVENKYIIKYKEEELV
                     IENLDKLNKLFFEKNEEQYNEFKHLKNIYEFATKAFPVDFPWTANLNYQ"
     gene            13878..14516
                     /locus_tag="KOU88_002529"
     CDS             13878..14516
                     /locus_tag="KOU88_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423639.1"
                     /note="Presence of a B(12) (cobalamin)-binding domain
                     implies dependence on cobalamin itself, in one of its
                     several forms, or in some unusual lineages, dependence on
                     a cobalamin-like analog; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin-dependent protein"
                     /protein_id="HBK3212400.1"
                     /translation="MDILDDIAECILNMGVDNIENLVKIAIDKNIDVEDIYEYGLNKG
                     MIGALDKFENKEYYLSEVIVCTDALNKGINLLKGTGKVKKKSKGVILMSVVEGDTHEI
                     GKNIVKVMVEATGYKVIDLGVNRKSEDIIEEAIKNNVDIIGLSSMMTTTMENMKSVID
                     ELNMIEIDKRPKVIIGGGPVSMEFAEEIGADGYSSNAPKAVKLINKLIGGEV"
     gene            14517..15539
                     /locus_tag="KOU88_002530"
     CDS             14517..15539
                     /locus_tag="KOU88_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HBK3212401.1"
                     /translation="MFSDMTLLQYINSEDRGFFLPDMGTNGLFLINKKAYEVYDSVDL
                     QLELAKTMDKYFESDFIYSFCDGITFCETLGLETLRPDYDFPSVLTHTITDRDKLRKL
                     DVPDPYTSGRMPLNIESLSVISKSIKKPLYESIQGPFTLAGQLAGATQLLRCIITDKK
                     FVEELLEFTTELVRRYAVAANKAGAKYISIAEPTSVTLSKDRFDEFIVKNLNKIYNEL
                     DCWKGMHICGDTRELLDNMLSCNIDAVSLDQILDYEEIAPMIPRDIVLIGNLDPIKLL
                     GRSKPDKIRRETLKLLKKMRRYDNFLCDFGCNCLNTTPVENLQAAIKAGRISYKELDR
                     IDIDEL"
     gene            15529..16149
                     /locus_tag="KOU88_002531"
     CDS             15529..16149
                     /locus_tag="KOU88_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212402.1"
                     /translation="MNYNSNKNKYLLKDINLDDIFIDKNIVLKFLGYGNRKAPDTISK
                     IVEREIRNINDILDIKIYISEVDINKTPKECKKAFAVLYTIGDKIDFKMNDYMENCNM
                     MAGLALDKIGIVCLDCINEKIKMYLKGKYDSLKISHEIYPGDKDFEVERQKDIYNYVK
                     NKYNSIEIEINDYHQLSPIKSVAMLILMGDEENLESRCSKCPRKCF"
     gene            complement(16276..16962)
                     /locus_tag="KOU88_002532"
     CDS             complement(16276..16962)
                     /locus_tag="KOU88_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBK3212403.1"
                     /translation="MKTYKFIFFDADDTLFDFKKSESHAFKKLLSEFDLEFNFENYIE
                     SYRNISDKLWLDLEKNIITLNELKLLRFELFANKISLDVDSETLSKMYLNFLGECTFL
                     IPGAIDILQYLKKKYTIVIITNGISAVQKKRLENSKIKGYIDGMVVSEELKISKPNPE
                     IFKYALKKFNCHDKSSALMIGDSLTSDVLGGINSGIDTCWLNSNNSINYTNHIPTYEI
                     NTLIELKKLL"
     gene            complement(16976..17521)
                     /locus_tag="KOU88_002533"
     CDS             complement(16976..17521)
                     /locus_tag="KOU88_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212404.1"
                     /translation="MNDLNLGEKIAEVRKKQNLSIRDLAKLADVTPSLLSQIERGLAN
                     PSVNSLKSIASSLNVPLFTFFVSEVDKKNLIVRHDNRKKVILPGSKEVIYEILIPDSS
                     GNLEFAIMDLAPNTSSCVDRITHNGDEIAYVLEGEVKLFMDDDEFTLSKGDSVKVPLG
                     TKHKWQNDSNSESKVIFAVIL"
     gene            17749..18996
                     /locus_tag="KOU88_002534"
     CDS             17749..18996
                     /locus_tag="KOU88_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HBK3212405.1"
                     /translation="MQITTFGAIFGLLIAIILIIKKFQAVYSLMLGAFIGGLVGGANI
                     TQTVDFMANGAMNISPSILRALASGVLAGSLIKTGAVDKISEQIVKIFGEKRALFSIA
                     ISTMVLAGVGVNLDVSIITVAPIGLYIGRKLNYSKLSILLAMLGGGKAGNIISPNPNT
                     IAVADNFSVNLSSVMMANIIPAIIGVVITVILASILINKGNKVQSYEILEQREDLPSL
                     FKSLCGPIIAIFLLFLGNVSPIVIDPMIALPIGGIVTLIVTGNLNNSREYLAFGLSKM
                     QGVCILLLGTGTIAGIIQMSELQQSTIGALQFLNMPQFLLAPVSGILMSLATASSTAG
                     ATIASSTFHDAIINGGLSPISGASIVNAGSSVFEQLPHGSLFHTSSGSINMDIGERFK
                     LIPYEALIGIVMTIISTSIQLVL"
     gene            19083..21077
                     /locus_tag="KOU88_002535"
     CDS             19083..21077
                     /locus_tag="KOU88_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBK3212406.1"
                     /translation="MNKKKIVIIGIIYSFLVVFSLTNMYVNMEYNLNVFEYIKKSLPF
                     TEEEKKWLEKHKNLIYSSDQSSPPLRYKGKEDGQYKGIIVDLINSLSIQIGRDFYFKP
                     NNWWKESFVNSIDDSIKFFDLIPSKERANKFIFTDPIYTLSANILKDKKSQDINSYMD
                     LKGKTVAIPEGDYSINFLKQKIQDINILLTPDIKTGVNHLMSGKVDVVVGDEPVLRYY
                     INNYGLSNKYSVLSNPIYTKKAVLAVPKQYEELVSILNKGIFKLQKNGVYKDLKKKWY
                     STYNEVDDILYERGIVPSIYLFIGIILISIYVFYSYTYLLKIEIKRKTEQVIENKKTL
                     EATFNSITDIIMLVDENNNIVESNKVLYDFMGEMSYKIADLISMIKGVIENTFSENTN
                     KTSEIEIHNKILKINTFPVEYKKNNTEYIVVLIKDITNDKIVEAKLLRENKMISIGQL
                     ASGVAHEIRNPLGIIRNNCYLLKDNVTMEEVNDCVKSIESNVDRASNIITNLLNFARI
                     SDDNLEHINIKNFIENIVKLQYKMLQLKNVEIKIDCEHNLICYINGESLKHVFINLIS
                     NSIDAIHQDGKIIIYCYEKNHCLFIDFKDNGEGIKEDVLKDIFNPFYTTKPIGEGTGL
                     GLYITYNEIKKNNGDISVESKLGVGTCFHIKIPLNKEVTI"
     gene            21077..22399
                     /locus_tag="KOU88_002536"
     CDS             21077..22399
                     /locus_tag="KOU88_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent Fis family transcriptional
                     regulator"
                     /protein_id="HBK3212407.1"
                     /translation="MKILLVDDELEYGVVMKKILQKKGYLVDIALSGEEAINIIKKDK
                     NYDLVLSDVMMKNMDGVQLLDRIKSINRDIEVILVTGYGSIENAVDAMKRGALSYFIK
                     SNPIENLLEEVEKVKASKISVSVQKNNFEFTLESKNRDFNNIIKIAKKAACKDVNILI
                     LGESGVGKDILARYIHSISPRKNEIFVPVNCCSFSENLLESELFGHEKGSFTGAVDSR
                     KGRFELSNKGTLFLDEIGDIPLNVQVKLLRTLEDKSIERIGSNKSIKVDFRLICAMNK
                     EPKVEISNGNIREDFFYRISTITITIPPLRKRREDLTTLIEFFLNKYQIEHDKKIHSI
                     DKEVKDFLLNYNYPGNIRELKNIINRLVVLSEEGNLSKDNLNLISNNVYIDDKISIRP
                     LREIRKEFECEYIEKVLSLCGNNISNTAKKLEISRRQLTNKISEYNIK"
     gene            22678..23964
                     /locus_tag="KOU88_002537"
     CDS             22678..23964
                     /locus_tag="KOU88_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006807454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine/sarcosine/betaine reductase component B
                     subunit"
                     /protein_id="HBK3212408.1"
                     /translation="MKLELGNIFIKNVEFGEKTEVKDGVLYISSEEIEKIVLEDERIV
                     SVNVELARPGESIRIAPVKDVIEPRVKIGDESKIFPGIINKVKTVGSGRTHVLLGACV
                     VTCGNIVGFQEGVIDMSGPTAKYTPFSKTNNICIVIKAKDGIDTHDYEEAARIAGLKI
                     GAYVGEAGREVEPDEVIVYETKPLLKQVKEYPDLPTVAYVHMLQSQGLLHDTYYYGVD
                     AKQIVPTFMYPTEIMDGAIISGNCVAPCDKVTTFHHLNNPVIHDLYKRHGKDLNFIGV
                     ILTNENVFLVDKERSSDMVAKLIEFLGVDGVLVTEEGYGNPDTDLMMNCRKCSEVGAN
                     VVLITDEFPGKDGKSQSIADATKEADAVVSCGQGNLVVHFPAMEKIIGTLDYVEMMIG
                     GYKGCLNEDGSMDAELQIIIASTIANGYNHLTARYY"
     gene            24050..25357
                     /gene="grdB"
                     /locus_tag="KOU88_002538"
     CDS             24050..25357
                     /gene="grdB"
                     /locus_tag="KOU88_002538"
                     /EC_number="1.21.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:25097..25099,aa:Sec)
                     /transl_table=11
                     /product="glycine reductase complex selenoprotein B"
                     /protein_id="HBK3212409.1"
                     /translation="MSKIRVVHYINNFFAGIGGEEKADIPPEKRAGVVGPGIAFQSQF
                     NDDAEIISTVICGDTYFGENIESATQELLKMIKEESPDLFIAGPAFNAGRYGVACGTI
                     CKAVEEELNIPVITGMYKENPGVDMFKLDLHIVSTGNSAASLRKVVPIMTKLGLKLVR
                     GEEIGPPEEEGYIMRGIRKNFFHELRGSERAIDMLVKKMKGESFETEYPMPEFDRVTP
                     MKPVKDLSKIKLALVTSGGIVPIDNPDKIESSSATKYGIYDLTDMDSMSNKEFTTIHG
                     GYDRAYVLENPNLVVPLDVVRELEKEGVIGELVDYFITTTGTGTSVGNSKRFGEEFSK
                     KLLEDDVDAVILTSTUGTCTRCGATMVKEIERAGIAVVHICTVVPISLTIGANRIVPA
                     VGIPYPLGNPMLGEEESKKIRKNIVLKALNALTEDIEEQTVFE"
     gene            25634..26365
                     /locus_tag="KOU88_002539"
     CDS             25634..26365
                     /locus_tag="KOU88_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3212410.1"
                     /translation="MIRKKVYILISIAICDDESYMLNHLKENIELYMKQKNLLYNIEL
                     FNKVEDLLCNHEKFNIVFLDIQMEEINGMQAARKLRSYGNECFIIFVTVLNEFVFDAF
                     EVDAINYLIKPLSNEKLYKTLDKIVTKLDDNESNYITIQKGYSYWKLKLADILYCEVI
                     KRKIYVHLKKETVDYYETIENLERSLPTNFFRCHRSYIINLQYVYGYENGNAVMESGD
                     RIPVSRLRQQIFSKVMLEFMKNRRI"
     gene            26367..27725
                     /locus_tag="KOU88_002540"
     CDS             26367..27725
                     /locus_tag="KOU88_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK3212411.1"
                     /translation="MINLFSSDLFLKYSFFFSFIVYRILMVIVQYYFLINFTNFNSKF
                     WCFILYSIISIFLIIINTYFNLYNLFSSQILFFLMTFLFVKYIIKQSTVLSIVSTLLV
                     YLIEQLVYGFTAPLNYLIFTSDINTDIYKFDINMGLSSLITIIIAGFIYWYSSKKFNI
                     KVMNFDKYIAILMIPLLLIILFMQSFEYSSNINIDTSLGIVKLLLNTSITEEIQAFLF
                     SIIGTICVFFSLFTFKKLIQALEDDKERAIMNQQIHAQKNYIEEAKSRLSQTISFRHD
                     FNNHLAIVNGLLKKDQILKAQDYLNKLEKVTSDLSFSCNTQNIVIDALFNNKLSIAKQ
                     LGIEVDCEVIIPQSTNMNDFDLCIVFANAIDNAIKACRVVDKQNRYLKLSTKLEGGFF
                     MIEIKNSYNPINNYTSGSGIGLLNIKEIAKKYQGAISIDKTSDYFQINVLLVISLHCA
                     SI"
     gene            27764..28249
                     /locus_tag="KOU88_002541"
     CDS             27764..28249
                     /locus_tag="KOU88_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212412.1"
                     /translation="MYLNRESLIYRNEEVTKMKVGNINGQAPITNGLDSCQSEVQGLE
                     QKKKALQDEIEKVRSDKSIDGETAKLKIEALKKEMEEIENKIQELKGNKGKKTNKEEN
                     NVSEVNNNLLERKKEPSNNENVKQLYDVFERSNVDEQWDNTYRVLQDDKNLKVKFNRP
                     I"
     gene            complement(28904..29128)
                     /locus_tag="KOU88_002542"
     CDS             complement(28904..29128)
                     /locus_tag="KOU88_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBK3212413.1"
                     /translation="MTVYNLKLGQKGIIDNIAGNEKLMKRLLALGLIDGTEVEVKKIA
                     PLNDPIVIRFRGFDLAIRKSDAKNINLKNN"
     gene            complement(29225..30478)
                     /locus_tag="KOU88_002543"
     CDS             complement(29225..30478)
                     /locus_tag="KOU88_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:glutamate symporter"
                     /protein_id="HBK3212414.1"
                     /translation="MITLSFDIVQTLTLSIFFFLIGNLLKNKVNFLNNFCIPAPVIGG
                     LLFCFLNLFFKYFNIADISISGNLMPNFITFFFTTIGLEISINLIKKGGSVLFRYWIL
                     CGVLAFCQNILAITISKIIKLEPLLGLMCGNVSMEGGHGYSAAFGLTIENLGIEGAVG
                     VGLSAATIGLIMGGILGCPVAKFLINKYKLKPSSNIDLSIPRYNRNLKRFGSKFFRNK
                     NRIKNNNFSETITPSVFLEQVLLIFICINTGEIISRCFYITFNILLPSVVTCMFSAVI
                     FRNLNDKINILELNFKLIDFLKELSLGIFLTLSLMNIDLFELSTLLPPILLIVTFQVI
                     FIILFSIFICFRVLGKDFDSAIIISGLIGHGIGATPNALANMSSLTQKYGDSPKAFLV
                     VPLVSGFLLDAISIPCILFFINILT"
     gene            30738..31727
                     /locus_tag="KOU88_002544"
     CDS             30738..31727
                     /locus_tag="KOU88_002544"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBK3212415.1"
                     /translation="MFENLPKIDLHCHLDGSVRVETMLDIAIKEKIDLPSNNMDEIKK
                     LAKVSFNCTSLDEYLEKFDLPLKVMQSKENLKRITFELLEDASRENVKYIEIRFAPLL
                     HTQKGMSVKNIIEGIIEGIREAESIYDIKGNLILGCMRTMTSKEALLVIEEGKSFVNK
                     GVVAVDLCGPEKEGFCKEYKDVFKLAREYGYKVTIHAGEAASGENVLDAINILKADRI
                     GHGVKIKDHKKAYNLVKDKKILLELCPTSNVQTKTVDSYEAHPFYTFYKDNLHVSINT
                     DNRTVSDINLSSELNVIFDTFKLGLEDYKIIYRNAVEASFADKETKEYLNSLI"
     gene            31799..32539
                     /locus_tag="KOU88_002545"
     CDS             31799..32539
                     /locus_tag="KOU88_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EcsC family protein"
                     /protein_id="HBK3212416.1"
                     /translation="MKDYEDVVYIKLVKKELEEWKKNILKKPSIFDKASKGIQNKFNG
                     VLPDKYHEIITSSIKVMTKTVLFGYKYATKPPLRNMSLEEREKLVLEKAKTYKTTAMI
                     EGAGTGAGGILLGLSDFPLLLGIKVKFLYDVASIYGYDVKDYRERIYILNILQLAFSS
                     QQHINKTFKLMNNWDEYVNSLPEDINDFDWRTFQQEYRDYLDLAKFLQLMPGIGAFVG
                     FYVNGKLIDKLCETAVSAYRLRIRELKL"
     gene            32755..33906
                     /locus_tag="KOU88_002546"
     CDS             32755..33906
                     /locus_tag="KOU88_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase"
                     /protein_id="HBK3212417.1"
                     /translation="MTNLPKQFDSFNEARQKGFINAKELKESGKKMVGVFCTFTPVEI
                     PMAAGATVVGVCGVSEEPIPDAERVLPRNLCPLIKSSYGHAITDTCPYFYFSDLLIGE
                     TTCDGKKKMYEELAKVKPTYVMHLPNTSKGEFAYKLWKDEMIRLKEEVEKSLGVTITE
                     EDIRTAIKDKNEERELLKEFYALGKLQPSALTGLELHNVLYQAGFKFDRAELKHSLRK
                     VIDDMKERYEKGECPVQKDKPRILITGSPIGGISEKIVKTLEDAGASVVAYELCGAIR
                     SNDLLVDEEIEDVYDALTQKYINIGCSCMMNNDNRIELLDRIIDEYNVDAVIDVVLQA
                     CHTFNIESYRIREFVTKEKNKPFMSLETDYSKSDTEQLRTRFEAFVEML"
     gene            33931..34686
                     /locus_tag="KOU88_002547"
     CDS             33931..34686
                     /locus_tag="KOU88_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyglutaryl-CoA dehydratase"
                     /protein_id="HBK3212418.1"
                     /translation="MFSIGVDSGSVATKGVLFDGEKIIKKIIIPTGWSPKSTSKQVYE
                     LLSSEIDKKDIKKVVGTGYGRGVMDFADKKVTEITCHTRGIYFLNKNIRTILDVGGQD
                     SKVINLDRDGNVFNFIMNDKCAAGTGRFLEITSNLLGSDIESIDTLAKGYEPVNISSM
                     CTVFAESEIVSLLAQNISTGEVAAGILKSIANKSTSMLARGEVIDEVAFTGGLAKSKE
                     LVKMIEEILGKKIFIAEDTQIIGALGAAVIGFR"
     gene            34878..37265
                     /locus_tag="KOU88_002548"
     CDS             34878..37265
                     /locus_tag="KOU88_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp13"
                     /protein_id="HBK3212419.1"
                     /translation="MKKFTSKKVTRFVALFLISILVMSTIPVSADNSNTLNQIKKAEY
                     SETYKQYLNDAKNGRTEKYNGIIPNPYQLEGTQIQSKGRTAPTSYDPRKLGLMTSIKN
                     QEDLGICWDFAAMATLESFLKLNNYGDYDLSEEHLRWWASDGEYGWSVDDMNGALNYE
                     AMGYLTSWSGPKLEKDIPYNGRVSKAQGAKKPTNMNTAPTVFNVTDAVCVSNDINSTK
                     NAILQYGAVTSGYYEDIKYQSDDQNSYYCPTKSFNTNHAISIVGWDDNYSKDNFNANI
                     RPSKNGAWLIKNSWGDYNSEGGYFWISYEDKTLMSDIDNFSIKGGKKPNDDEKMYQHD
                     YASIVPLISKKITAANVFDFNRGDETLKSVMFLTESIGAKYEVYYAPVVNGIPQENNM
                     KKLKEGTAQYSGYITVPIDSFDIPEGKGAIVVSIEGKNGESTIGSESNVPGYDTFKAK
                     ANLGESYIIDNTGKFFDINRDSNFYPCNFTIKAVTEKSSGESIPNESLIGSDRYETAI
                     KVSQNGFNSSENVVLVNGSSIVDALAATPFTSAINSPILLTQKEALNSKTKAEIQRLG
                     AKKVYLIGGENSISKEIEQQLKSLNISIERISGSDRYKTSLLLAQKLNGIKNVSQIAV
                     VNGVKGLADAISVGAAAAENNIPIILANEKSELQGADEFLNSLNIEKSYIIGGTASLS
                     NNLESKLKNPTRLSGSSRDETNSKIIDNFYKKDTLKNAFVVKNGIKNQNDLIDGLAVG
                     PLGAKTGSPVILVGDKLADSQKEVLKNKTLEKVTQVGGGANKNAFKELVKLKSAK"
     gene            complement(37496..37729)
                     /locus_tag="KOU88_002549"
     CDS             complement(37496..37729)
                     /locus_tag="KOU88_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBK3212420.1"
                     /translation="MATTTKNRFYDYVQENLNKYVEVHSYFSSCPLYGEIIEADSLSI
                     TLCSRYIDESNPTLNETYTLYLPLSSIISIRTL"
     gene            38019..38609
                     /locus_tag="KOU88_002550"
     CDS             38019..38609
                     /locus_tag="KOU88_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3212421.1"
                     /translation="MPKSYSDKEREYIIKRLKEEARLCMEQYGIRKTTVDELVKRVKI
                     PKGTFYLFFQSKELLFFEVLRDIHDSIQKEILYEINRVDESITCEQLTDIFMKFYRMV
                     DSTSILNLMINGEFEILVRKLPDSIIEEHFRHDDFEIGEIISCIPNAKNKDIESFSGA
                     FRAVFLTMLYKREVGSNCFEDALRLMINGLVIQLME"
     gene            38723..39568
                     /locus_tag="KOU88_002551"
     CDS             38723..39568
                     /locus_tag="KOU88_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212422.1"
                     /translation="MIKVDDLSFSYTDRDFLQNINFEVGKGEILGFLGPSGAGKSTLQ
                     KILIGMITNYGGSVIVNGVESKRHSNKFYENIGVDFEFPSLYEKLTAIENLKYFGSLY
                     SKKLLSIDELLKSVGLENEANKRVSEYSKGMKSRLNFIKALLHNPDILFLDEPTSGLD
                     PSNSKVMKDIILSEKSKGKTIILTTHNMLDATELCDRVAFIVNGKISALDTPHNLIMS
                     KGAIKVRYTYFDNGEKTSECFLNNTANDKNLNMLIEKNKLLSIHSSEPTLNDIFIEIT
                     GRNLQ"
     gene            39565..40248
                     /locus_tag="KOU88_002552"
     CDS             39565..40248
                     /locus_tag="KOU88_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212423.1"
                     /translation="MRLKNLILGDIKFQFKYGFYFLYLFLSIIYICIINVFPTFMREK
                     IAIIMIYSDPAAMGLFFMGAIVLLEKSQRVLNSLAVSPVKVSEYILSKVISLGVISSI
                     VAMFIAITLNLDNIIISTIGTFFSSIIFSLLGLIIASKASSLNQFIVLSIPIEIICFI
                     PPILNVLLDTKSYANLYPFNICISLISGNKNFIMINILILISIIIIIYFITYYFICSS
                     WKKVGGVKL"
     gene            40245..40961
                     /locus_tag="KOU88_002553"
     CDS             40245..40961
                     /locus_tag="KOU88_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212424.1"
                     /translation="MIKIINAFKQEFEQIKRDAMLFIVCVSPILCGVFIKFGIPLIQN
                     ISLNKFYYQLNLEPYFLMFDLLLAFITPFMFFFASTMVILGEIDDSISRYLIVTPLGK
                     TGYLISRFGIPGILAFVITMILLIFFSLTKISFLLNLSISLLVLLQGIIISILVISLS
                     SNKLEGMVITKFSGVFMMGILAPFFILNKAQYILFFLPTFWISKAFKEDNYIYMFISI
                     VISLIWILLLFKKFSKKIVK"
     gene            41058..41321
                     /locus_tag="KOU88_002554"
     CDS             41058..41321
                     /locus_tag="KOU88_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212425.1"
                     /translation="MKNKIKILREKLGLTQEQLGRLVGTSRQAINAIETGKNEPSIWL
                     AYDISRIFNEPIESVFLFEESERKSRAQISRGEYYGYKKDKNI"
     gene            41293..41748
                     /gene="def"
                     /locus_tag="KOU88_002555"
     CDS             41293..41748
                     /gene="def"
                     /locus_tag="KOU88_002555"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBK3212426.1"
                     /translation="MAIRKIRTFDDEILRKKSKYVENVDNKIREILNDMAETMYNTPN
                     GGGLAACQVGVLKRLVVIDLGEGLIKLVNPEIIKQEGEQIVVEGCLSFPEVWGKLKRP
                     KKVTVQALNEYGEKIEIKGSGFMAKCLCHEIDHLNGIVFTDKIIEHVKL"
     gene            41800..42261
                     /locus_tag="KOU88_002556"
     CDS             41800..42261
                     /locus_tag="KOU88_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine dimer DNA glycosylase/endonuclease V"
                     /protein_id="HBK3212427.1"
                     /translation="MRLWHKDLIDVLPKNQLVSQWRELLAIKGSIDKKGTPNHVLVNK
                     VLNYSIDEFKFYTKIVHDEMLKRNYKPNELKYTSILKWKNRNFANDISNEHSLNLENL
                     YDDWHNKMYLKQCLYNLEEKATCGGIPINEWNILLCKYSKDYELWSGNIMF"
     gene            42311..43213
                     /locus_tag="KOU88_002557"
     CDS             42311..43213
                     /locus_tag="KOU88_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3212428.1"
                     /translation="MYNKIKYIPINCEIACNKLKRSMPYKWDLNIYRGCEHGCKYCYA
                     IYSHKYINSNNYFEEIYVKTNIVEKLERQLKSSKWKKEVINIGGVTDSYQPIEADYKI
                     MPEILNLLIKYKTPAIISTKSDLILRDYDLIDKLSRITYINVASTITTVNEDTQRLIE
                     PNGVDSMRRFKMLKEFRKTNASVGLHIMPIIPYITDDFDNINSLFRHAKECNVHYVLP
                     GTLYLRGITRGVFFDFVKKEFPELFDKLSILYSAGSLNREYKNQLYKMVNELRYKYSL
                     SSSYSKIMKEKLKNSGDVQISFFD"
BASE COUNT        16971 a         4730 c         6793 g        14740 t
ORIGIN      
        1 agtctgtgct tacatgaaag tgtaagaagt tcataagaga actgcatagg tagtagcgag
       61 cttatgtgaa cgacaacctc aaaaatgata aaagttaaga cttacggttc ttaaatatgt
      121 tatttaaaat taaatataaa accttctaaa taattgtttt aaataattac atttgttaat
      181 attatgatag gtggttaata aattgttcac cacagcatta tataatatat taaaatcatt
      241 aaaaagtgta tcaaaaaaca attaaagtga ggtgatagca gtgaaaaaag cttataagtt
      301 tagactgtat ccaaataaaa agcaacaaga gttaattaac aaaacttttg gatgttgtag
      361 atttgtatat aataagtatc ttgctaaaag aatagatgtt tataaaaaca ataaagaaac
      421 ttttacttat aaacagtgta gttctgattt gaccaattta aaaaaagaat taaaatggct
      481 taaagaacct gacaaatttt cactacaaaa cgccttaaaa gatttagata atgcatataa
      541 aaaattcttt aaagaaaaag caggatttcc taaatttaaa tcaaagaaaa ttaatagatt
      601 ttcatataaa actaacttta caaatggaaa cattatgtat tgtggtcaac atataaaact
      661 acctaaactt ggtatggtta aggtaaggga taaacaagta cctaaaggta gaatacttaa
      721 tgctactata tctaaagagc caagtggtag atattatgta tcattatgct gtactgatgt
      781 agatattgaa gcatttgaaa atactaacaa tcagataggt ttagatttag gaattaaaga
      841 attttgtatc tcaagttgtg gagaatttat agaaaatcct aagtatctta agaagtcatt
      901 aaacaaactt gttaaattac aaagcgaatt atcgagaaaa acaatcggta gtttaaatag
      961 aaataaagca agattaaaag ttgcaagact tcaagaacat atagctaatc aaagaaagga
     1021 ttttctacaa aaactatcta ctaaattaat aaaaaagaat gatattattt gcatagaaga
     1081 tttacaagta aagaatatga ttaaaaatca taaactatct cgctcaattt ctgatgtgtc
     1141 atggtcagaa tttattcgtc aattagaata caaggctaat tggtatggta gacaaattgt
     1201 aaaggtaggt aaattctttg caagttcaca aatatgtaat aaatgtgggt ataaaaacga
     1261 ggaagtgaag gacttaaata taagagaatg gatttgtcct agttgtaatg aaactcacga
     1321 tagagatata aatgcaagta gaaatatatt aaaagaagga ttaagactaa taacaattca
     1381 aaataaataa cgtatgtaag aaccgtagga actacgggga tagcctgtgg agaattagta
     1441 agacatattt tagtatgcaa aattctgtga agcaggaacc ctgtgacttt agtcatggga
     1501 ggttcagggt agaaagataa atgaactttg taaagatgaa gttgtagagt tttgcaatag
     1561 aataaaaggt aaagtggaaa gtgttgcaat aagtggagta tttgctccag taaataaaca
     1621 acaagaagaa gaagttgcaa aatgggttag agaaatttta ggggatattc ctatatcttt
     1681 atcaaatgaa ataggtaata taggtatatt agaaagagaa aatggagcta ttttaaattc
     1741 tgcattgtct caagtaggta aagctgtatc tttaggattt gaaaaagcac ttaaagactt
     1801 aggtatagat gctcaaatat atttcagtca aaatgatgga acattaatga atttagagta
     1861 tacaatgaaa tacccaattt ttacaattgg atgtggaata acaaattcta taagaggagc
     1921 ttccttctta tcaaaagtaa aaaatgcaat agtattagat gttggtggaa ctacaagcga
     1981 cttgggtgta ctatataatg gattccctag agaatcatct attccagtta caattggagg
     2041 agtacataca aactttagaa tgccagatgt tttaactatt ggtcttgctg gtggtacatg
     2101 tgtaaaaggc gaaaaagata atataaagat aggtcctgaa agtgtgggat atagaataac
     2161 tgaagatgca ataatatttg gtggagacac tctaacttta tcagatgttg ttacaaaatt
     2221 agatatggcg tttgaagata gaaaaagcaa tgttgaaaac ttagataaag agtattgtaa
     2281 tgaggtatat aagaaggtta ttttaaaatt agaagatgct gtagaccaaa tgaagactag
     2341 tcaagatgat gttgaattgg ttttaactgg tggaggaagt ataattgttc ctgaaaaact
     2401 aaaaggcata agcaatgtta taagacctcc tcattatact gctgcaaatg ctattggtgc
     2461 agctttagga caaataagtg gagatgtaga aaaagtatac agtttagata aaatgtcgag
     2521 agaagatgcc atagaagatg caaaaaaaga ggctgtaaat aaagctctaa aagctggtgc
     2581 taaagaagat actatagaag tattaaatat agaagatgtt ccacttgcat accttcctgg
     2641 taatgcactt cttataaaag taaaagttgt tggtgattta atttaaagaa taaatataag
     2701 tatttccaga attatataaa tatttctgga ctcattttta aacttatttt atcaataaaa
     2761 acagcataac ttttgactat attcttataa gtttccgaac agccgatata tacctatttt
     2821 ttgaggttta tcggctgttt gtcatctttt atcgcattcc aactattttt cttaccgtat
     2881 ttgctgtacg aattgtaatc ttatcactta catttgaact ggcagtcttt gaccaccaat
     2941 ttgtcttttt ataatcttta cgactaaaag accaaaagat agcattttta taatgatata
     3001 ctttttcata ctcttcttta ggatttccaa cctcatcata aaactcgtca taagataagt
     3061 caggaaacat aaaaataaga ttatcatata tttctttgtt gttatctccc caccaattag
     3121 gagcattatt tagtatatct tttaactcct cttgtgaaat aataaaaact ggtatttcca
     3181 attcaaactg tttttttatc attaatctta ttgtatttga gataactttg ctgtcatcta
     3241 catcacttaa aaagacaaca ttaccactat taaggtatgt agaaacttct gaataaccaa
     3301 gttctacaaa gcttgctttt aattcagaca taattatctt gttcttacca cttatattga
     3361 tacctcttaa taatgcgata taacttttca tataataatt tcacctctaa acattcacat
     3421 ttttctatgt agtacaaact tgaatttgca tcttttataa ttctttcaaa acttcttcat
     3481 atgtaatttt tttaatataa aaaaatcggt gcttaatttg taccgatttt tgtttttcct
     3541 agtaaagaac tcgttttttt gcttctgcta tagctctagc agcacttttt gcttgcattc
     3601 ttttttcttc ttctttttta aattcattta ttgtttcatt tagattctta tcatgttcat
     3661 ttttttcttt atcttcgttt tctctgtata ctaatatata atctattatt gattcgttta
     3721 ttatttgaga tatactttta ttttcattaa ttcctattct cttaacttcc ttaagtagag
     3781 tctcatcaat atgaaccgtt gtttgctttg tattttttgc caccttaatc acctcttaaa
     3841 aaaaattcta acattaaaat tttttttagt caataaattt taatattaaa attctttaaa
     3901 tgttttattt gattttctaa aattttctat tgtatttatc atcttatttt ttatattttc
     3961 acctagtaca gaagacttta gtctaggatt ttcgatatgg tcataaattg gttctaaaaa
     4021 ttcgacttcg acaggaacag agttaatttt accaataggt tggtatcctt cataagtatc
     4081 ttttgaattt tttattacta gtggaacaat agggcatttt gctttatatg ctatctttaa
     4141 agctccactt ctaaactccg aaaccaatga atttggttct ttaatccatg ttaaatctcc
     4201 ttctggaaac actgccatac tttgacctgt aagtatattt tgagaggctt gggctatact
     4261 ctttatacct tcacgattgt tttttctgtt tacatataca catcttagta attttgccca
     4321 ttctttaaat ataggtatat ttctccaaac tggttcatct gcaattacac atccaattgg
     4381 tctttctaca cttgctgtta gtatgaagct gtcaagcata ctagaatgat ttacaacaaa
     4441 tagaagtggt tcttttggca gtgtttcctt accaattata ttaagctcta tgttcactat
     4501 atctaaagat tttttagctt gtttttgcat aaattcaaat ttttccttta agctaaattt
     4561 atcaggattc tttttaattt taataagcct aggtatagaa gatgtaaaac ctataagttg
     4621 atatgtagca aattttaagt aattattcat aaaattatct ccttaaaata aaattattta
     4681 ttactgtaaa gattttaaca taaaataaaa tttaagtcta ttttaattca attttgtaac
     4741 atatatttta aatagacaga gattgagatt ttatatttcc aattttagta atcagatttt
     4801 atcaataaat tactattcta ttaatttaat taaataacct ttaaatttaa ttataaaaac
     4861 tgttgcagaa atttctacaa cagtttaaaa aatttacctt acaaaaactt attttataac
     4921 aagagagtat attataaggc tagtacagcc cattttttgc actgagaaat tcttttgcca
     4981 tcatcacctt gttctttgtc atatgcaaat tgattaagca tttcacatgg aaatgtatca
     5041 catagaccac aatgtgtaag gtttttatct tcacaacaag attttacagg acattgttca
     5101 ccccaaaatg gtttctcaat ctctgtacaa cctttacaat tgactttttc cttgtatcca
     5161 cattcataac ataaaattcc acatcttgat tctatcattt taagtcactc cttaaatata
     5221 aattttatat gattgtatat caaaatttat acttttcatt gtaaaaatcg gacaaatttt
     5281 ttatataggt tgttggatta acaccacaaa tagatttaaa atcatttata aaatgagatt
     5341 ggtcgtaata accaatatct tgtgctaaag ttgcaaaggg tattttatta ttttgtattt
     5401 cttgtaatac aaggtttata cgaagtaatc taaggtatga tttaacactc ataccaagag
     5461 aattattaaa aattctattt aaatgtcgtt cactataaca actaatttgt gaaatgtttt
     5521 taacagacat aatagagttc tgttttctag cattttcaag aattggtata gtcatatcta
     5581 ctatatttga tttcaataag tatgataaga ataacatatc taattgttct actaattcct
     5641 ttatagtact tgttctttca aaaatggaat taacctctaa gctaaataat gtgttaaaat
     5701 cttcaagtga aatttttaaa tctgtagatt ctctttgaga aagacctgtc aaataatata
     5761 ctccacctgg gcgaaactca acgaatactc taaaaagtac attttctata tcatttttta
     5821 caatagtagt ttttgttgtg gctccccaga atgcgctttc tatacctttt ttgtcaaatt
     5881 taaatatcat acatccacta gcatcaggta ttaatgtaag attttcttta atacttgtat
     5941 ctggaataga tattgtatag tgtgctatat actgtcttaa caatttatgt ggcaaaatat
     6001 atgtatactg tttgcaggta tttaaaatgt tattgattat tttattcata agtatatcct
     6061 cctgatatat aaaaaataag tatactaatt tattttttat ataataaagc agttttgttt
     6121 taattgaaat attctaataa gatattttgt taaatttaga tacaataatt gtaaagtaaa
     6181 atctcaaaat atacaattat tataaatcat agatatttat taaataaata tattaaagaa
     6241 gaaggaatat aaaacaagat tagaaaataa tagtgttact ttcataataa atacatataa
     6301 agatattttt aagaataaaa tttattatta aataaaaaat aaaggagagt gatttaatag
     6361 catggcatca aaacaaatac caagaaacaa tttagaaaag tttttaagaa taagagtctt
     6421 atcacataca ggcgataaaa tacatataaa gttacctgta aattttgcaa agagaatgat
     6481 tgagaataat gctttggatt tatttaatgg aaaagatgat gtagtagatg gtaaaaaagt
     6541 tactgaaata ttagttaagg catttgacta tgatttaact ggagaagtag ttcacttgga
     6601 gagaaaaaat ggagacatta ttaaagtttc aattgtacaa tagaattatt ttatatgaat
     6661 tttatttttg aatagttata aataattaga aatttgtaaa aaagtataat atattattag
     6721 taatggtaca gaatacacat ttataattta tagatgtgta ttttttgttt aaaaaattta
     6781 aatatataaa actataaagg ttacaatttt ggaaatagat gtaaatatat gttgtattgt
     6841 ataataagag taatataaaa tctagtaaaa ataatcaaat aaatttagct tatgagaggg
     6901 ataactatgg aaaataagga ttttaaatta acaatatgta tatttgcttt tgtaattgga
     6961 gtagtagtat tattctgttg tataggttta ggtgaattta gtgcagagca tattattcaa
     7021 caaaatggtg gaatcatgga tactgaccaa tataatattt atctagacca atctatttct
     7081 caatatagaa attttggttc tatattagct ctgttaggag gaatagggat attgtttgat
     7141 aaatatatca gaaaatacta gagattatgt tttgtctaaa ataaattctt atgaggagat
     7201 aaaaaatggc aacagaaata tttactgtaa aaattacacc cttagaggca caaaaaatga
     7261 taaaagaaaa tcttgatgca gatttagttt ttagtgattc ttataattta ggagatgata
     7321 aatttatact aattacaact tttgagaagt attatgcaag aaataatagt gatgcaggat
     7381 taatagtagt ttatgaaaat accacaggaa aaacagttat taaagctact tcaacaggca
     7441 gtgcaattgg aattttaaaa attgattggg gtgcaggtgg aaatttactt aaaagagtaa
     7501 aaaacatact tgctgattat attatttaat tattttatct aactgataat atgtcaagaa
     7561 aatctcgtaa aagaggttaa gaacattttt ataatatata gataaataag aatttgaagg
     7621 taaagttttt aaggtataaa gaaaaataat ataataaaac gaattggctt tataattctt
     7681 tataaggcaa agagcacatt tctttatata attgttggat attaaataat atgtaaatac
     7741 accatttaca tataaaagtt taattaatat gttaagagaa aatgaaatgg aaattactaa
     7801 aaaatatttt taaattggat aatggttgat attatgttta tacaaaaatc atgtagaatt
     7861 ttatatattt taaatatgat agtttaaaat tatgaaagaa tgataaattc cagtttgtag
     7921 ggtaattttg ataaataata ttaataagta tgagtaaaaa gtaggagcat attaatataa
     7981 cgtccctact tttttattat taaaattgtt tataatatca acactacatt aaaacacaac
     8041 ctaaatttga aaaacaaata gtttagaaat atgtactttt ttatctatta tattctttta
     8101 aatcgaattt tttcatctga acataaagtc tcaaatctat atgcgtctgt catatcataa
     8161 aaaccaaaaa atataaagcc atcacgagaa gtaaattcat attgtatatt ttcaattttc
     8221 aacatgtttt ctacttcgct tattttttca ctatatataa tttctaccat ataatttatc
     8281 attgtagaat ccctcctatt aatatgaaaa tatccaaata tataataaca tatttagatg
     8341 atataatagt atccaaataa aaaataatct tattacatta ttgaatgaag aattaaaatg
     8401 aagataaata aaacaaatat tggttataat tgattaaaaa atagttatgt atacttgtga
     8461 ctttagttat gggcagttca agttttatga aagaagtcat atatatatgg aatattctag
     8521 gcagaaattg tttaataata agagaatact ataaaaattt gagtattaca taaaaaataa
     8581 gaagccatag atgatataag cattatctat agcttcttac ttctcattga ttaagattat
     8641 atataaaaat aatcactata ttttttgttt aagttttagt acttgtttta ctatatttgt
     8701 tgagtggtca gaaattcttt ctagattagt aagtaagtca agataaagta caccagcatc
     8761 aattgtacaa cttccattat ttagtctaat catatgtgaa tttctaaaag ttttttctaa
     8821 ataatttact tcattttcaa cttctaaaac tttatttgct aactcaaaat ctttaacatc
     8881 taaaactatt aaggcatcct taaaattagt aattgtctta ttgtatattt cgtatatttc
     8941 tcttatcgca ctatcagaaa aactaatgtt catttcctta acactcatgg ccaattcagc
     9001 tatattttct gcatggtcag agactctttc aatgtcattt acagtattaa aaagcaaatc
     9061 tgttctaaag cgttcatcat ctctaagagg ttctttagaa agttttaaca aatagttcaa
     9121 tatatctttc tgtaacttat tgacaacttt ttctgactca aaagctttat taatatcttc
     9181 attgctctta tttaaaaatc ctgcaattga atgttccaaa gagtttgtag ctttatgacc
     9241 cattcttaca acttcttgta cagtattacc aagtgctata gatggagtgc taaacatcct
     9301 ttcatctaag tacttagtat tatttactat ttctgattca gtttctttaa taggtataag
     9361 tctatttgct aatttaacta tgtatttaga aaatggtaat aatattataa catttgtaag
     9421 attaaataaa gtatgtgcat ttgctatttg tctagctgta tcagttgggt caaaatgagt
     9481 aactatggct gatataggtt tatttaaaac aagcataaat attattgtac caattacatt
     9541 aaaacttaaa tgcattacag ctgcacgtcg agcatttcta cttgcaccaa cacttgataa
     9601 aagtgaagta acacaagtac ctatattatc tccataaaga ataggtaaag cagatgatag
     9661 aggaagtatt ccttgagaag ctagtgctat caacataccc atagatgcac ttgaactttg
     9721 aacaatacca gttatggcaa atcctgccaa tatacctaat acaggatttt tactaaaata
     9781 taaaagtgca tcagtgaatg ctttatattc agcaagtgga gctactgcat ctttcataaa
     9841 ctccattcct gtaaataata taccgaaacc tataagtatc tcagataaat gctttgtttt
     9901 ttgatttgat gtaaataaat agaataaaat acctatacct aaagcaattg gtgcaattcc
     9961 ttcaagatta aatgaaacta attgagcagt aactgtagta cctatatttg cccccattat
    10021 tacaccaata gcttgactta gattcattat acctgcattt acaaatccta caaccataac
    10081 agtagtagca cttgaacttt gtataatacc tgtaacgact gtacccacca gtacacccat
    10141 aacaacatta cttgttaaga gttcaataat tttttttaat ttgtctcctg ctgatttttg
    10201 taaaccttct cccattaaac tcattccgta aagaaaaagt ccaagtccac cgataaggct
    10261 aattactata ttcacgatat ttcctccctt aagaaattaa taattttttt atctgaatta
    10321 taaactttat taactaaaat ttattgtttc cataatatag aataacaaat tttgtcaata
    10381 aaaatattaa tgttttgtta agtatacgtt aagagaatgt taaattttta agttgttgtt
    10441 aattttagaa aatttatgat atatagcaat ttaaatactt gaacttagat ttttagtatt
    10501 ttatgtacaa tcaatttaac aaagaattaa ctataattgt aaaaaatatg taaaaaaata
    10561 acatcctttt agaatgatat tttttagtta taaatatttt tatattcaat tggtgtaaag
    10621 ttattaaact ttttaaaaat tatactatag taattttgac tattgaatcc aattagtaca
    10681 gcaacgtcta aaatagacaa gtcttttttt aatatatact ttttgctttt ttcaactcta
    10741 actttattta aaaaattagt aaaagtatat ccactttttt tcttaaacaa agaaaaaaac
    10801 aacttttatt aagttataat tcattacata tattacttac tgttatatct tctgagtaat
    10861 ttttgtgaat ataatctata gttttcttta agttttcttt acataaaact aagagttggt
    10921 ctatgtttca ttttatccag gcatatttat taaaaaatca atctctattt gttaaaataa
    10981 tttatgaatg atgttagaaa ctgtaatata ttggatataa tataataaac agataaactc
    11041 tgtattaaga ggatatatag tttatcttaa ttatagggga agtgaggata tattatggaa
    11101 agattaatgg aactcataga aagaaaattt ttaaaggatg tagaactttt agaattagaa
    11161 gacatagaaa atgtaataga atgcaaaatg acacagccat ataatgctca ttataatgaa
    11221 tacttagtaa aagtaaaaaa tggagatgaa gtagaagaat attttgtgta tttaaaacat
    11281 agataaacat aaaagaggtt tatatttatt tgtatgatta taaaataaat acaagcctct
    11341 ttttttgata aatataaaat tataaaattt ttatttattt aattttttca acaacattag
    11401 tcaatattga atctaaatca tcactaattt ctgtaactcc attatgagta atatctataa
    11461 tttctttagt cataggaagt tctcctaaaa gttctaagtc taaatcatct aaaaactttt
    11521 cagtagattc tccttcaaat aacttgattt ttttagaaca atcaggacat tggatataac
    11581 tcatattttc aataactcca aggacattta tgttcatttt tttagccata ttaacagctt
    11641 ttgatacaat catagatacc aaatcttgag gtactgaaac cataactatt ccacttatag
    11701 gaatagattg cataactgtt aaggcaacat ctccagtacc aggaggcata tctattaata
    11761 aatagtctaa ttcttcccaa agtacatcag tataaaattg ctttacaacc cctccaagta
    11821 aaggtcctct ccaaacaaca ggttcatttt catcatctat cataaggttt atagacatta
    11881 cttttatgtt atttgagttt tctacagggt aaatataaga gccatcagaa taagctttta
    11941 cattttttac acccataagt ctaggaatac ttggtccagt tatatctgag tctaatatac
    12001 caaccttata tcccattttg tttagcttat tagcaagtaa agcagttaca gttgattttc
    12061 caactccacc cttcccactc ataacaccaa ttatttttcc aaatttattg ttagggttat
    12121 tttcaataga acaatttgat tgactattac aatttccctt tgatggacat gaattacaat
    12181 ctgccatatc tattacctcc aaactttaat atttattaga ttatttgtaa cctacatata
    12241 ctattttagt acaattgaac cataaagtca ttatttaaaa gcaacttaga agattttcta
    12301 ttgatttatt catagactat agcaaaaaga atacaataaa aaaattataa cattcttgaa
    12361 aaagtgatta tttcaattta gttatagaac ttagtcatat aaatatatag aaaatatttt
    12421 aatatattat acataacggg ttattttata agtttaacta taaattaggt ttatatttta
    12481 taaaaatttg ctaaaaaaaa caattaaaaa ttgtaaagaa aaaagatata attagaactg
    12541 tagtaataaa tgttttatta tagataatag agttttaagt atcttaaata atatttggag
    12601 gaatatgaat ggaattaaga ccaagaagtg caaaattaga agaatttgat aaagtaatag
    12661 aattaataaa ctatgtattt agaatatcaa gaagtcataa accaactatg atggaagaat
    12721 ttcctctttt actaagtaaa aataatatag aaaatatgat tataatatca gaagatgata
    12781 aagtggtttc tgatgtaaac tatctaattc aggatgtatc tattcaagga aacagattga
    12841 aggttgcagc tataggtgga gtatgtactc atccagatta tgaaaagaga ggctattcat
    12901 ctaagatatt ggataaagta gaagaaaaaa tgttttatga tggtgtagat attgtaatta
    12961 tatcaggaac aagaagtcta tacagtagaa gaaattgtag tttggtaaag agtttttata
    13021 aatatacaat aaaacctgaa gatgtaaaaa tagcatatga aatagttgaa tttgatgaaa
    13081 ctaattttga aaaagataat gatttagata aaatgattga actatataat caaaatagta
    13141 ctagatttat aagaacgaga gatgagtttc aaaaactatt gcatgcagca actattgcct
    13201 ggggaccaat tggttacaag aaggtattta taaaggaaaa taataatata ataggatatt
    13261 tgataataag aacaataaaa aaagaagatt ctactgtagg agaagttgct gaaatagggt
    13321 taaactctgt aaatgttgaa aatatattga aatatgttgc aaataaattt ggattagaat
    13381 atttaaatta taaagtacat gtgaaaaatc ttaaagacca gttgaaatgt aatgggacaa
    13441 aatctttgga ttatcaacaa ggaactatga aaataataaa ttttactaag ttgtgtgata
    13501 gtttaagaag ttattttagt caatatgtag attttgaatt actaaaatac atggaattta
    13561 aacaagttga aaataaatat attattaaat acaaagaaga agaacttgta atagaaaatt
    13621 tggataagct taataaactg ttttttgaaa aaaatgagga acagtacaat gaatttaaac
    13681 atctaaaaaa tatatatgaa tttgctacaa aggcatttcc tgtagatttt ccatggactg
    13741 caaatttaaa ttatcaatag ttttagatga tattaaataa aattgattga tacctagagt
    13801 tagtccttgt taaataagag aaattattgg atattgaaaa agcaattttg taagtaatta
    13861 gaaaggatga gtattatatg gacatacttg atgatatagc agaatgtata ttaaatatgg
    13921 gtgtagataa tatagagaat ttagtaaaaa ttgctataga taaaaatatt gatgtggaag
    13981 atatttatga atatggttta aacaaaggta tgataggagc tttagataag tttgagaata
    14041 aggaatacta tctttcagaa gttatagtat gcacagatgc attaaataaa ggtattaatc
    14101 ttttgaaggg aactggaaaa gtaaagaaaa aatcaaaggg agtaattctg atgtctgtag
    14161 tagaaggaga tactcatgag ataggaaaaa atattgtaaa agtaatggta gaagccactg
    14221 gatataaggt tattgactta ggtgtaaata gaaaaagtga agatataata gaagaagcta
    14281 taaaaaacaa tgtagatata ataggcttat cttcaatgat gacaactaca atggaaaata
    14341 tgaaatcggt tatagacgaa cttaatatga ttgagataga taaaagacca aaagtaataa
    14401 ttggtggagg tcctgtaagt atggagtttg cagaagaaat aggagcagat ggatacagtt
    14461 caaatgctcc aaaagcagtt aaattaataa ataaacttat aggaggtgaa gtttaaatgt
    14521 tttcagatat gactttactt cagtatataa atagtgaaga tagaggtttt tttctgcctg
    14581 atatgggtac aaatggattg ttcttaataa ataaaaaggc atatgaagta tatgatagtg
    14641 tagatttgca attagaatta gcaaagacta tggacaagta ttttgaatca gattttatat
    14701 actcattctg tgatgggatt acattttgtg aaactctggg tttagagaca ttaagaccag
    14761 attatgattt tccaagtgta ttgacacata ctataactga cagagataaa ttaagaaaat
    14821 tagatgttcc agacccttat acgagtggac gtatgccact caatatagag agcttatcag
    14881 ttatatcaaa aagtattaaa aaaccactat atgaatcgat acaaggtcca tttacacttg
    14941 caggtcaatt agctggagct actcaacttt taagatgtat aataactgat aaaaaatttg
    15001 tagaagaatt attggaattt acaactgaat tggtaagaag atatgctgta gctgcaaata
    15061 aagcaggagc aaaatatatt tcaatagcag agccaacatc agtaacccta agtaaagata
    15121 gatttgatga atttatagta aaaaatttaa ataaaatcta caatgaactt gattgttgga
    15181 aaggtatgca tatatgtgga gacaccagag aattattaga taatatgcta agttgtaata
    15241 tagatgcagt aagtttagac caaattttag actatgaaga aattgctcct atgattccta
    15301 gagatatagt tttgattggt aatttagacc caataaaact tcttggacgt tctaagccag
    15361 ataagattag aagagagacg ctaaaattgt taaagaagat gagaagatat gataactttt
    15421 tatgtgattt tggttgtaac tgcttaaata ccactccagt agaaaattta caagcagcta
    15481 taaaggcagg aagaattagt tataaagaat tagataggat tgatattgat gaattataat
    15541 agtaataaaa ataaatatct tttaaaggat ataaatttag atgatatttt tatagataag
    15601 aatattgtgc taaagttttt ggggtatgga aatagaaaag ctccagatac aattagtaaa
    15661 atcgttgaaa gagaaataag aaatataaat gatattttag atatcaagat atatataagt
    15721 gaagttgata ttaataaaac acctaaagaa tgtaaaaaag catttgctgt actatataca
    15781 ataggggata aaattgattt taagatgaat gactatatgg aaaattgcaa tatgatggca
    15841 gggctagcat tggataaaat aggtatagta tgtttagatt gtattaatga gaaaataaaa
    15901 atgtatttaa aaggaaagta tgatagtctc aaaatatcgc atgaaatata tccaggagat
    15961 aaagattttg aagtagagag acaaaaggat atttataact atgtaaaaaa taaatataat
    16021 agtatagaaa tagaaatcaa tgattatcat caactatccc ccataaaaag tgttgcaatg
    16081 cttattttaa tgggggatga agaaaattta gaatcaagat gtagtaaatg tcctagaaaa
    16141 tgcttttaga tagttttcaa gagtaagatt tgttttgtgt atgaataatt gcaataattt
    16201 ttttggtcat tttatgtata aactaaaaaa attattgcaa agtaatattc tatttaattt
    16261 gaacagactt acaaactata atagtttctt taattcaata agtgtattta tttcataagt
    16321 tggtatatga ttagtataat ttatactgtt attggaattt aaccaacaag tatctattcc
    16381 tgaatttatt ccacctaaga catcagaggt taagctatcc ccaatcatta aggcagaaga
    16441 tttatcatga caattaaact ttttgagagc gtatttaaat atttcaggat ttggttttga
    16501 tattttcaac tcttcagata caaccattcc atcaatatat ccttttattt ttgaattttc
    16561 aagtcttttc ttttgaactg cagaaattcc atttgttatt ataacaatag tatacttttt
    16621 tttaagatat tgtaatatat cgattgcacc tggaattaaa aatgtacatt cacctaaaaa
    16681 atttaagtac attttgctaa gagtttcaga atcaacatcc aaagatattt tatttgcaaa
    16741 aagttcaaat ctaagtaatt taagttcatt caaagttata atattttttt caaggtcgag
    16801 ccaaagctta tcacttatat ttctatatga ctctatataa ttctcaaaat taaattctaa
    16861 atcaaactca gatagaagtt ttttaaaagc atgtgattca cttttcttaa aatcaaataa
    16921 agtatcatct gcatcaaaaa atataaattt atatgtcttc atggttttta ctcctttaca
    16981 agatgactgc aaaaattact ttactttcac tatttgagtc attttgccat ttatgctttg
    17041 ttcctaaagg aacttttaca ctatctcctt tggacaaagt aaattcatca tcatccataa
    17101 aaagtttaac ttctccctcc aaaacatatg caatttcatc tccattatga gtaatcctat
    17161 caacacaaga agaagtgttt ggagctaaat ccataattgc aaattctaaa ttaccactag
    17221 agtctggaat taaaatctca tatataactt ctttgcttcc aggtaaaata actttttttc
    17281 tattatcatg tcttactatc aagttttttt tatctacttc agatacaaaa aatgtaaata
    17341 aaggaacgtt tagagaagag gctatagatt ttaatgaatt tacagatgga ttagcaagac
    17401 ctcgttctat ttggctcaat aatgatggtg taacatcagc tagttttgct aaatctcgaa
    17461 tacttaagtt ttgttttttt cgaacttcag ctattttttc ccctaaattt aaatcattca
    17521 tataaatatc ctctcttttt aatttaaaaa atattaactt aaaataatca agtaaaatga
    17581 ttatgtagta tgaaattatt ataacatata gaattaggtt ttgaaaaaac tatgttcaat
    17641 ataattaaat aaattaaaat ataattgaca aagtggatac agaatactta aaatatattt
    17701 aaataaaatt aagcaaaaga tagttaattt atgataggag gggatattat gcaaataacg
    17761 acttttggag ctatatttgg tttattaata gcaattattt taattataaa aaaatttcaa
    17821 gctgtatata gtttaatgtt aggagcattt attggaggat tagttggagg agcaaatata
    17881 acacaaactg tagattttat ggcaaatgga gctatgaata tatcaccatc aattcttaga
    17941 gctttggcat caggtgtatt agctggaagt ttaataaaaa caggggcagt agataaaata
    18001 tcagaacaga ttgtaaaaat atttggtgaa aagagggctt tattttcgat tgccatttca
    18061 actatggtac ttgctggagt aggtgtaaat ttggatgtat ctataataac tgtagcacct
    18121 ataggattat atataggtag aaaattaaat tattctaaat tgtcaatact attagctatg
    18181 ttgggagggg gtaaagcagg taatataata tcaccaaatc caaatactat agcagtagca
    18241 gataattttt ctgtcaatct ctctagtgtt atgatggcaa atataattcc agcaattatt
    18301 ggagttgtta ttacagttat tttagcaagt atattaataa ataaaggaaa caaagtacaa
    18361 tcatatgaaa ttttagagca aagagaagat ttaccaagtt tatttaaatc attatgtggt
    18421 ccaattatag ctatatttct attgttttta ggaaatgtat ctcctatagt tatagacccg
    18481 atgatagccc ttccaatagg aggaatcgta actctaattg tcacaggaaa cttgaacaat
    18541 tcaagagaat atttagcttt tggattatct aagatgcaag gggtatgcat attattactt
    18601 ggaacaggga ctatcgcagg aattatacag atgtctgaat tacaacagag tacaataggt
    18661 gctttacaat ttttaaatat gccacaattt ttattggcac cagtttcggg tatacttatg
    18721 tcattagcaa cagcatcatc aacagctggt gctactatag catcatctac ttttcatgat
    18781 gctataataa atggtgggct atcaccgatt tcaggtgcat caatagtaaa tgctgggtct
    18841 agtgtattcg agcaattacc acatggctca ctatttcata ctagttcagg tagtataaac
    18901 atggatatag gtgaaagatt taagttaatt ccatatgaag cattgatagg aatagtaatg
    18961 actataattt caacatctat tcaattagtt ttataataaa tataaatatt taatgaaaaa
    19021 agtaggattt tgttattaaa tattgaattt attatagtaa aaaagaagat tggagtttta
    19081 aagtgaataa aaaaaagatt gttattatag ggattattta ttcattttta gtagtatttt
    19141 cacttacaaa tatgtatgta aatatggagt ataatctaaa tgtatttgaa tatattaaga
    19201 agtcacttcc atttacagaa gaagaaaaaa agtggttaga aaaacacaag aatttgattt
    19261 acagctctga ccaaagttca cctcctttga gatataaagg taaggaagat ggacagtata
    19321 agggaattat tgttgattta ataaattctc tgtcaattca aattggtaga gatttttatt
    19381 ttaaaccaaa taattggtgg aaagaatctt ttgtaaattc aatagatgat agtataaagt
    19441 tttttgactt gattccatca aaagaaaggg caaataaatt tatatttact gacccaatat
    19501 acactttgag tgcaaatata ttgaaagata aaaagtccca agatataaat agttacatgg
    19561 atttaaaggg gaaaacagta gcaattccag aaggtgatta ttctataaat tttttaaagc
    19621 aaaaaattca agatataaac attttgttga ctccagatat aaagactgga gtcaaccatt
    19681 taatgtctgg aaaagtagac gtagttgttg gtgatgaacc agtattgcga tactatataa
    19741 ataattatgg actttcaaat aaatacagtg ttttaagtaa tcctatatat actaaaaaag
    19801 cagttcttgc tgtacctaaa caatatgaag agctggttag tattttaaat aaaggcattt
    19861 ttaaacttca gaaaaatgga gtgtataaag atttaaagaa aaaatggtat tctacgtata
    19921 atgaagttga tgatatattg tatgagcgag gaattgtgcc tagtatttat ctttttatag
    19981 gtataatttt aatatcaatt tatgtttttt atagctatac atatttgtta aagatagaaa
    20041 tcaaaaggaa aacagaacag gtaatagaaa ataaaaaaac tttagaggca acttttaata
    20101 gtattacaga tataataatg cttgtagatg aaaataacaa tatagtagaa tcgaacaaag
    20161 tactatatga ctttatgggt gaaatgagtt ataagatagc agatttgatt agcatgataa
    20221 aaggtgttat tgaaaatacc ttctctgaaa atactaataa aactagtgaa atagaaatac
    20281 acaataaaat tttaaagata aacacttttc ctgtagagta taaaaaaaat aatactgagt
    20341 atatagtagt tcttattaaa gatataacta atgataaaat agtagaggcg aaattactta
    20401 gagaaaacaa aatgatatct ataggacaat tagcttctgg ggtagcacat gagataagaa
    20461 atcctttggg tataataaga aataattgct atctcttaaa agataacgtt acaatggaag
    20521 aagtaaatga ttgtgttaaa tcaatagaaa gtaatgtaga tagagcaagt aatataataa
    20581 ccaacttgtt aaatttcgca agaatatcag atgataattt agaacatata aatataaaaa
    20641 attttattga aaatatagtg aaacttcaat ataaaatgtt acagttaaag aatgttgaaa
    20701 taaaaattga ctgtgaacat aatttaatat gctatataaa tggagaatcg ttaaaacatg
    20761 tatttataaa tttaatttct aattcaatag atgcaataca tcaagatgga aaaattatta
    20821 tatactgtta tgaaaaaaat cattgtttat ttatagattt taaagataat ggtgaaggaa
    20881 taaaagaaga tgtcctaaag gacatattta atcccttcta tacaacaaaa ccaattggtg
    20941 agggaactgg tttaggttta tatattactt ataatgagat taaaaagaat aatggagata
    21001 taagtgttga aagtaaattg ggggttggaa cttgttttca tataaaaatt ccattaaata
    21061 aagaggtgac tatataatga aaatactatt agttgatgat gagctagaat atggagtggt
    21121 aatgaaaaaa attctacaaa agaagggcta tcttgtagat atagcactaa gtggtgaaga
    21181 agctataaat ataattaaaa aagataaaaa ttatgatttg gttttatctg atgttatgat
    21241 gaaaaatatg gatggagtac agctattaga tagaattaaa tctattaata gagatataga
    21301 ggttatatta gttacaggat atggaagtat tgaaaatgca gttgatgcta tgaaaagagg
    21361 agctttatct tattttataa aaagtaatcc cattgaaaat ttattagaag aagttgaaaa
    21421 ggtaaaggca agtaaaatat ctgtttctgt acaaaaaaat aattttgaat ttactttgga
    21481 atctaaaaat agagatttta ataatatcat aaaaatagca aaaaaagctg cttgtaaaga
    21541 tgttaatata ttaatcttgg gggaatctgg tgtaggaaaa gatatattag ctagatatat
    21601 acatagcata agtccaagaa agaatgagat atttgtacct gtaaattgtt gttctttttc
    21661 agaaaatcta ttggagtctg agctgtttgg tcatgaaaaa ggttctttta caggagcagt
    21721 agatagtaga aaaggtagat ttgaactttc gaataaagga actctatttt tggatgaaat
    21781 aggagatata cctctaaatg ttcaggtaaa acttttgagg acacttgagg acaaatctat
    21841 agagaggata ggaagtaata aatctattaa agttgacttt aggttaattt gtgctatgaa
    21901 taaagaacca aaagtggaaa tatcaaatgg aaatataaga gaagattttt tttatagaat
    21961 aagtacaata acaataacta taccaccact aagaaagaga agagaagact taactactct
    22021 tatagaattt ttcttaaata agtaccaaat tgaacatgat aaaaagatac actcgattga
    22081 taaggaagta aaggattttt tattaaatta caattatcca ggaaatataa gagaattaaa
    22141 aaatataata aatagacttg tagttttaag tgaagaaggt aatttatcaa aagacaattt
    22201 aaatttaata tcaaataatg tatacataga tgataaaata agtattagac ctttaagaga
    22261 aataagaaaa gagtttgaat gtgagtatat tgaaaaagtt ttatctttgt gtggaaataa
    22321 tatttcaaat acagctaaaa aattggagat tagtagaaga cagttaacca ataaaatatc
    22381 agagtataat attaagtgag aaaaaaactt ctcattaagt gagaaaaaaa tttctcaaac
    22441 tgtattaaaa gataaacaga aaaaatctgt ttatcttttt ttattataat tttaaaaatt
    22501 aatatttaca ataattattg ctaaattcaa tattggtgta aattaaaaat gaaaatttct
    22561 atgacattaa tacatagaat atatatttta aataattggc atagaaaatg ctttatatat
    22621 taataaacgt aataaatact tttaattgcg attaaatata ttaaggggga ttttcatatg
    22681 aagctagagc tagggaatat atttataaaa aatgttgaat ttggagaaaa gacagaagta
    22741 aaagatggag tactatatat tagtagcgaa gaaatagaaa agatagtatt agaagatgaa
    22801 aggattgtaa gtgtaaatgt tgaacttgca agacctggcg aatcaataag aatagctcca
    22861 gttaaagatg taatagagcc tagagttaaa attggagatg aaagcaaaat atttcctgga
    22921 attataaata aagtgaagac tgtaggaagt ggaagaaccc atgtactttt aggagcttgt
    22981 gttgtaactt gtggaaatat agttggattt caagaaggcg taattgatat gagtggtcct
    23041 actgctaaat atacaccttt ttcaaaaaca aataatatat gtattgttat aaaagcaaag
    23101 gatggtatag atactcatga ttatgaagaa gcagctagaa ttgcaggatt aaaaataggt
    23161 gcatatgtag gtgaggcagg aagagaagtt gagccagatg aagtcattgt atatgagaca
    23221 aagccattat taaaacaagt aaaagaatat ccagacctgc caacagtagc atatgttcac
    23281 atgttacaat cacaaggact tttacatgac acttattact atggggtgga tgctaaacag
    23341 atagtgccta catttatgta tccaactgaa ataatggatg gagctataat atctggaaac
    23401 tgtgtagcac catgtgataa ggttacaaca ttccatcatt taaataatcc agttatacat
    23461 gacttatata aaagacatgg aaaagattta aactttatag gagttatttt gactaatgag
    23521 aacgtattct tagtcgataa agagagaagc tctgatatgg tagctaaatt aatagaattt
    23581 ttaggagttg atggagttct agtgacagaa gaaggttatg ggaatccaga tactgaccta
    23641 atgatgaatt gtagaaaatg tagtgaagtt ggagcaaatg tagttttgat aacggatgaa
    23701 tttcctggaa aagatggcaa gagtcaatct atagcagacg ctactaagga agcagatgca
    23761 gttgtttctt gtggtcaagg aaatctagtg gttcatttcc cagcaatgga aaaaattata
    23821 ggaactttag attatgttga aatgatgata ggtgggtata aaggatgctt aaatgaagac
    23881 ggaagcatgg atgcagagct acaaattata atagcatcaa ctatagcaaa tggctataat
    23941 catttgacag caagatatta ttaaataagt atttgaatat aaagttctgt tgatgtaatc
    24001 attggtctaa ctgatgtaat aactataaag tgatttggag gattaagaga tgagtaaaat
    24061 cagagtggtt cattatataa acaatttctt tgctggtata ggtggagagg aaaaagcaga
    24121 tattccgcca gaaaaaaggg ctggtgtagt aggacctgga atagcatttc agagtcaatt
    24181 taatgatgat gcagagataa tctcaactgt aatttgcgga gatacgtatt ttggtgaaaa
    24241 tattgagagt gcaactcaag aacttttaaa aatgataaaa gaagaaagcc ctgatttatt
    24301 tattgcaggc ccagcattta atgcaggtag atatggagta gcttgtggga ctatttgtaa
    24361 ggcagttgaa gaagagttaa atattcctgt aattacaggc atgtataaag aaaatccagg
    24421 tgtagatatg tttaaattag atttgcatat agtgtctaca ggaaattcag cagcaagtct
    24481 tagaaaggta gttccaataa tgacgaaact aggtcttaaa ttggttagag gtgaggaaat
    24541 aggacctcct gaagaggaag gatatataat gagaggaata agaaaaaatt tcttccatga
    24601 acttagaggg tctgaaagag caattgatat gttggttaaa aagatgaaag gggaaagctt
    24661 tgaaactgag tatccaatgc ctgaatttga tagagttaca cctatgaaac ctgttaaaga
    24721 tttatctaag ataaaacttg ccctagtaac ttctggaggg atagttccaa ttgataatcc
    24781 agacaaaatt gaatcttcaa gtgctactaa atatggaatt tacgatttaa cagatatgga
    24841 ttctatgtca aataaagaat ttacaactat acatgggggg tatgacagag catatgtcct
    24901 tgaaaatcca aatttagttg taccactaga tgtagttaga gagcttgaaa aagaaggtgt
    24961 aattggagaa ttagtagatt attttataac tactacagga acaggaacga gtgttggcaa
    25021 ttctaagaga tttggagaag agttttctaa gaaattgtta gaagatgatg tagatgctgt
    25081 aattttaact tctacatgag gtacttgtac tcgttgtgga gcaacgatgg taaaagagat
    25141 tgagagagct ggtatagcag ttgttcatat atgtacagta gtaccaatat cacttacaat
    25201 aggagctaat agaattgttc cagcagtagg gataccatat ccacttggaa atcctatgtt
    25261 aggagaagag gaaagtaaaa aaattagaaa gaatatagtt ttaaaagctt taaatgcact
    25321 aacagaagat atagaagaac aaacagtatt tgaataataa aaatacaaca caacactgaa
    25381 ataaaaaaag atatcaaaaa ataatttttt aaaattattt tacgatatct ttttttatta
    25441 ggtaaattcg aaatttgcat ttttttaaat taaatttata aaagtgataa attagtttat
    25501 tataatattg atacacaaat tcaaattaga tatactatga aaagcgagat tattacattt
    25561 tggaacaaat attcaacata ttagatcata ttaattgaac agaaaaaatt aactttatat
    25621 aataattaga ataatgataa gaaagaaggt gtatatattg atttcaattg ccatttgtga
    25681 tgatgaatcc tatatgctaa atcatttaaa ggaaaatata gaattataca tgaagcagaa
    25741 gaatttatta tataatatag agctttttaa taaagtagaa gatttactat gcaatcatga
    25801 aaagtttaat attgtatttt tagatataca gatggaagag attaacggaa tgcaggcagc
    25861 tagaaaatta aggtcatatg gtaatgagtg ctttataatt ttcgttacag ttttaaatga
    25921 atttgtattt gatgcttttg aagtagatgc tataaattat ctgataaaac ctctatctaa
    25981 tgagaaacta tataaaactt tggataaaat agttacaaaa cttgatgata atgaaagtaa
    26041 ttatatcaca atacaaaaag gttattcata ttggaaatta aaacttgctg atattttata
    26101 ttgtgaagtt ataaaaagaa agatttatgt tcatttaaag aaagagactg tagattatta
    26161 tgagactatt gaaaatttag agagaagttt accaacaaat ttttttaggt gtcatcgtag
    26221 ttatataatc aatttacaat atgtatatgg atatgaaaat ggtaatgcag ttatggaaag
    26281 tggagataga atacctgttt ctagactacg tcaacaaata ttttcaaaag ttatgcttga
    26341 gttcatgaaa aataggagga tataagatga ttaatttatt ttcttccgat ttatttttaa
    26401 agtacagttt tttcttctct tttattgtat atagaatttt aatggtaata gtgcaatact
    26461 attttctaat caattttaca aattttaatt caaaattttg gtgttttatt ttatattcga
    26521 taatttcaat ttttttaatc attataaata catattttaa tttatataat ttattttctt
    26581 cacagattct attttttctt atgacttttt tatttgtaaa gtacataata aaacaatcta
    26641 ctgttttatc tatagtatca actttgttag tatatttaat tgaacaatta gtatatggat
    26701 ttacagctcc attaaattac ttgatattta ctagtgatat aaatacagat atttataaat
    26761 ttgatataaa tatgggacta tcttctttaa ttactattat aatagctgga tttatatatt
    26821 ggtatagttc taaaaagttt aatattaagg tcatgaactt tgataaatat atagcaattt
    26881 tgatgattcc attgttgctt ataatattat ttatgcaatc atttgaatat agttcaaata
    26941 taaatataga tacaagtctt gggattgtaa agctgctatt aaatacttct ataactgaag
    27001 aaattcaagc ttttcttttt tctataattg gaactatatg tgtatttttt tctctattta
    27061 cctttaagaa actaattcaa gctctcgaag atgacaagga gagggcaatt atgaatcaac
    27121 agattcatgc tcaaaaaaac tatattgaag aagcgaaatc acgattatca caaactatat
    27181 cctttagaca tgattttaat aatcatttag ctattgtcaa tggattgttg aaaaaagacc
    27241 aaattttaaa agcacaagat tatttaaata agcttgaaaa agtaacaagt gacctatcat
    27301 tttcttgtaa tacacagaat attgttattg atgctctttt caacaataaa ttaagtatag
    27361 caaaacaatt aggcatagag gtagattgtg aagtaattat accccaaagc actaacatga
    27421 acgattttga cctatgtata gtgtttgcta atgctattga caatgcaatt aaagcttgta
    27481 gagttgtaga taaacaaaat aggtatttaa agctttccac taagttagag ggtggatttt
    27541 ttatgataga aataaaaaat agctataatc caataaataa ttatacaagt ggctcaggta
    27601 taggtctttt aaatataaaa gaaattgcta aaaaatatca aggggctata agtatagata
    27661 agacatcaga ctattttcaa ataaatgtat tgctagttat ttcattacat tgcgctagta
    27721 tttgagaaca atttcattga aaatagtatt tgtaagctat attatgtact tgaatagaga
    27781 aagtttgata tatagaaatg aggaggttac taaaatgaaa gttggaaata taaatggtca
    27841 agcaccaatt acaaatggtt tagatagttg tcaaagtgag gtacaaggct tagaacaaaa
    27901 gaaaaaagca ttacaggatg aaatagagaa agtaagaagc gataaaagta ttgatggtga
    27961 aacggccaaa ttaaaaatag aagctttaaa aaaagaaatg gaagagattg aaaataaaat
    28021 tcaagagtta aaaggaaata aaggaaaaaa aacaaataaa gaagaaaata acgtttcaga
    28081 agtaaataat aatctattag agagaaaaaa agaaccttct aataatgaaa atgtaaaaca
    28141 attatatgat gtttttgaaa gaagcaatgt agacgaacaa tgggataata cttatcgtgt
    28201 tctccaagat gataaaaact taaaagtaaa atttaataga cctatatagt ttatttataa
    28261 aaatagttaa tattttaatt atcaccactt tttagaagaa tacacacttt attttaaaga
    28321 cccacatatt tatttacagt tagcacattt atatgtggtt ttataactat tatttacaag
    28381 tctatattga taacttttac atagtatata atgtttaaat acttattcaa atttatctat
    28441 acataaacaa aaaaagagat tttaaaatct ctttttagat tgttgactta tggctttttg
    28501 atttaataaa atcaagaagc cgtttgaatt ttatatgttg gctgataccc ttctgatatt
    28561 gaaacaccat ttttgtttcc aaaatcgttt aaaattaaga acttattatg aatgactatt
    28621 tcattatgaa caataagcaa ataacatgaa tcttcaatca atgttttaac agtagcatta
    28681 aatgcttgct tatatagttc tatcgtttgt ttgaactgcc cattaaagta aatatgagtc
    28741 aataacataa ctatatctac acaaattaat ataaattttt tatactgtac attatctaac
    28801 tgttgattat ctgtattaca acatgattga atttaaaaag ccatcaacac atagaatgtt
    28861 gatggcctga aaatagattt taaaatctct tttttattat atattaatta ttttttaaat
    28921 ttatattttt tgcatcagat tttctaatag ctaagtcaaa ccctctaaat ctaatcacta
    28981 tagggtcatt aagaggagct atctttttca cttcaacttc agtgccatct attagtccta
    29041 aggctagaag tctcttcata agtttttcat ttccagctat attgtctata attccctttt
    29101 gtccaagttt taagttgtaa acagtcatta ttaacacctc ctaatgaaaa tcattatcaa
    29161 actttatatt tataatatat aacaaaaaga gcaaattgtc aatatataac aaaaaataaa
    29221 catactaagt tagtatgttt ataaaaaata gtatacatgg gatactaata gcatctagca
    29281 aaaaaccact tactaatggt acaactaaaa aggcttttgg agaatcacca tatttttgtg
    29341 tcaaagaact catatttgcc agagcgttcg gagtagctcc tattccatgt ccaatcaaac
    29401 cacttattat gatggcagaa tcaaaatctt ttccaagtac tctaaagcaa ataaatattg
    29461 aaaataggat tataaagatt acttgaaaag ttactattaa gagaatagga ggtaataatg
    29521 tagataattc aaataaatct atattcataa gtgataaagt taaaaaaatt cccaatgaaa
    29581 gttcttttaa aaaatctata agtttaaaat ttaattctag tatatttatc ttatcattta
    29641 aatttctaaa aataacagcc gaaaacatac aagttacaac agagggtaat agtatattaa
    29701 acgttatata gaagcatcta cttataattt ctcctgtatt tatacaaata aatatgagaa
    29761 gaacctgttc caaaaataca gatggtgtta ttgtttcgga gaagttatta ttttttatcc
    29821 tattcttatt tctaaaaaat ttacttccaa atctctttag atttctatta tatctaggaa
    29881 tcgacaagtc tatatttgat gatggtttta atttatattt atttattaga aatttagcta
    29941 caggacatcc caatatacca cccataataa gtcctattgt tgcagcagat aatccaaccc
    30001 caactgctcc ttctataccg agattttcta ttgtaagtcc aaatgcagca gaataaccat
    30061 gaccaccttc catagataca tttccacaca taagccctaa aagaggttca agttttataa
    30121 tctttgatat tgtaatagct aatatatttt gacaaaatgc caatactcca cacaaaatcc
    30181 aatatctaaa taatacacta ccacctttct ttataagatt tatgcttatt tcaagtccta
    30241 tagttgtaaa aaagaaggtt atgaaatttg gcattaaatt tccacttata gatatatctg
    30301 ctatattaaa atatttaaaa aataaattta gaaaacaaaa taatagacct cctattactg
    30361 gtgcaggtat acagaaatta tttaaaaagt taactttatt cttcaataaa ttaccaatta
    30421 aaaagaagaa tatagatagt gtcaaggttt gcactatatc aaaacttaag gtaatcaaaa
    30481 taagtcctcc tttgtaattc aaagttttaa ttatataact taaattctta tgtattgaaa
    30541 ttttattatc aaatgtatat taataaatgt atattaaaaa gaatcagtag atataattag
    30601 atagtcataa attaaattaa aatattttaa tgagatatga cttttttaga attaaaaacc
    30661 gtagtatatt gatataatag aaataagact taaaaatctg ttgatagtat tatttataag
    30721 tacagtagga ggataaaatg tttgaaaatt tacctaagat agatttacat tgccacttag
    30781 atggaagtgt tagagtagaa accatgcttg atatagctat taaagagaaa atagatttac
    30841 cttcaaataa tatggatgaa ataaaaaaat tagcaaaggt ttcttttaat tgtacttcac
    30901 tagatgaata tttagaaaaa tttgatttac ccttaaaagt aatgcaatct aaggaaaatt
    30961 taaaaagaat tacttttgaa cttttggaag atgcaagtag agaaaatgta aaatatattg
    31021 aaattagatt tgcaccatta cttcacaccc aaaaaggtat gagtgttaaa aatataattg
    31081 agggtataat tgaaggaatt agagaagctg aaagtattta tgatataaaa ggcaatttaa
    31141 tattaggttg tatgagaaca atgacctcaa aagaggcatt attagtaatt gaagaaggga
    31201 aatcatttgt aaataaaggt gttgtagcag tagacttgtg tggtccagag aaagagggat
    31261 tttgtaagga atataaagat gtttttaaat tagcaagaga atatggatat aaagttacaa
    31321 tacatgcagg agaagctgca agtggagaaa atgtattgga tgctataaat attttaaagg
    31381 cggataggat tggtcatggg gtaaaaatta aagaccataa aaaggcgtat aatttagtta
    31441 aagataaaaa aatattgctt gaattatgtc caactagtaa tgtacaaact aagacagtag
    31501 attcttatga agcacatcca ttttatactt tttataaaga taatttacat gtaagtataa
    31561 atactgataa tagaactgta tcagatataa atttaagttc agaactaaat gttatatttg
    31621 atacttttaa actaggatta gaagactata aaataattta tagaaatgca gtagaagcta
    31681 gttttgcaga taaagaaact aaagagtatt tgaatagttt aatttaatag ataaaaatat
    31741 ttaaacttta aattaagcta ttaaattgat aaaaatacat tgtattagga gaaaaaatgt
    31801 gaaagattat gaagatgttg tttatattaa actagtcaaa aaagaacttg aagaatggaa
    31861 gaaaaatata ttaaagaaac cttctatatt tgacaaagca tcaaagggta tacagaataa
    31921 atttaatgga gtattgccag ataaatatca tgaaataatt acttcttcta taaaagtaat
    31981 gacaaaaacc gtactgtttg gatataaata tgctacaaag ccaccactta gaaatatgtc
    32041 attagaagaa agagaaaaat tagttttaga aaaagctaaa acttacaaga ctacagcaat
    32101 gattgaaggg gcaggaacag gggcaggagg aatcctctta ggtttatctg attttccttt
    32161 gcttttaggt attaaagtga aatttttata tgatgtagct tcaatatatg gatatgatgt
    32221 taaagattat agagaaagga tttatatatt aaatatatta cagttggctt tttctagtca
    32281 acagcatata aacaaaactt ttaaattgat gaataactgg gatgaatatg taaatagtct
    32341 accagaagac atcaatgatt ttgattggag aacatttcaa caagagtata gggattattt
    32401 agatttagct aagtttttac aactaatgcc tggaatagga gcatttgtag gattttatgt
    32461 gaatggaaaa ttaattgata aattatgtga aactgctgtg tctgcttata gattgaggat
    32521 tcgagagctt aagttataag aaaaattata acataaaaaa ttagttatac aatatatcta
    32581 tatgtatcta attttgcatt gataaaaaca attatggata aaaggtaaag catgatagaa
    32641 tctaatgtag aggtttgtat tttaatggaa aaatttagtt tttattgctt aagatacaaa
    32701 ttgaattacg aagagattga attatgaaga gaaataattg ggaggaatat tttcatgaca
    32761 aatttgccaa aacaatttga tagcttcaat gaagctagac aaaaaggatt tataaatgca
    32821 aaggaactta aggaaagtgg gaaaaagatg gttggagttt tctgtacatt tactccagtt
    32881 gaaattccaa tggcagctgg agcaactgta gtaggtgtat gcggcgttag tgaagagcca
    32941 atacctgatg cagaaagggt gcttccaaga aatctttgtc ctttaattaa atcaagctat
    33001 ggacatgcaa taacagatac ctgtccttat ttctattttt ctgatttgtt gataggagaa
    33061 accacttgtg atggtaagaa aaaaatgtat gaagaacttg caaaagttaa gccaacatat
    33121 gtaatgcatt tgccaaatac ttcaaaagga gaatttgcct ataaactttg gaaagatgaa
    33181 atgataagat taaaagaaga ggttgagaaa tctttaggtg taactataac tgaagaagat
    33241 ataagaactg ctataaaaga taaaaatgaa gaaagagaac ttttaaaaga gttttatgca
    33301 cttggtaaat tacaaccatc tgcacttaca ggccttgagt tacataatgt tttatatcaa
    33361 gcaggtttta aatttgaccg tgcagaactt aaacattctt taagaaaagt tatagatgat
    33421 atgaaagaaa gatatgaaaa aggtgaatgt cctgttcaaa aagataagcc aagaatattg
    33481 ataacaggtt ctcctattgg tggaataagc gaaaaaatag ttaaaacttt agaagatgca
    33541 ggggcatcag tcgttgcata tgaactttgt ggagctatta gatcaaacga tttattggtt
    33601 gatgaagaaa tagaagatgt atatgatgct ttaacacaaa aatatataaa tataggttgt
    33661 tcttgtatga tgaataatga caatcgtatt gaattattag atagaataat agatgaatat
    33721 aatgtagatg ctgtaataga tgtagtttta caagcatgtc atacatttaa tatagaaagt
    33781 tatagaataa gagaatttgt tacaaaagaa aaaaataagc catttatgtc tcttgaaact
    33841 gattattcaa aatcagatac tgaacaatta agaactagat ttgaagcgtt tgtagagatg
    33901 ttgtaggaat aaataaaagt aggaggaact atgtttagta taggagttga ctcagggtca
    33961 gtggcaacaa agggtgtgct atttgatggt gaaaaaatta ttaagaaaat aattatacca
    34021 actggatgga gccctaaaag tacatctaaa caggtctatg agttgctaag tagtgaaatt
    34081 gacaaaaaag atataaaaaa ggtggtaggt acaggttatg gaaggggagt aatggatttt
    34141 gctgataaga aagtaacaga aataacttgt catactagag gtatttactt tttaaacaag
    34201 aacataagga ctattttaga tgtaggtggt caagatagta aagttataaa tttagataga
    34261 gatggaaatg tatttaactt tataatgaat gataagtgtg ctgcaggaac tggtcgattt
    34321 ttagagatta cttctaacct tttaggaagc gatattgaaa gtatagatac attagctaaa
    34381 ggatatgaac cagttaatat atctagtatg tgtacagttt ttgctgagtc tgaaattgta
    34441 agtcttctag ctcaaaacat ttctactgga gaggtagcag cagggatact taaatctatt
    34501 gcaaataaat ccacctcaat gttagcaaga ggtgaggtaa tagatgaagt tgcatttact
    34561 ggagggcttg caaaaagtaa agaactagta aaaatgatag aagaaatact gggtaaaaaa
    34621 atttttattg cagaagatac tcaaataata ggagctttag gagctgctgt aataggattt
    34681 agataaaaac atataaaaag aaaatgagaa gctgaattta ttataaataa attcagtttt
    34741 ttattttatt ttatttattt ataaaggaaa actttggtat aattgattta aatgattgta
    34801 tatttgtaaa tacttgatat ttagtcatat ataacattat aattttaaaa attagctcaa
    34861 aataaggggg agaaagcgtg aaaaaattta cttcaaaaaa agtaacaagg tttgttgcgc
    34921 tgtttttaat atctatttta gtaatgtcaa caattcctgt atcagctgac aatagcaata
    34981 cattgaatca gataaaaaaa gcagaataca gtgagacgta taaacaatat ctaaatgatg
    35041 ctaaaaatgg acgtacagaa aaatataatg ggattatacc aaatccatat cagttggaag
    35101 gtactcaaat ccaaagtaaa ggaagaacag ctccaacatc ttatgaccct agaaaattag
    35161 gtcttatgac atcaataaaa aatcaagagg atttaggaat ctgttgggat tttgctgcaa
    35221 tggcaacctt agaaagtttc ttaaagttaa ataattatgg agactatgat ttatcagaag
    35281 aacacttaag atggtgggct tcagatggtg aatatggatg gtctgtagat gatatgaatg
    35341 gtgctttaaa ttatgaagct atgggatatt taacatcttg gtcaggtcct aaattagaaa
    35401 aagatatccc atacaatggt agagtatcta aagcacaagg agcaaaaaaa ccaactaata
    35461 tgaatacagc acctactgtt tttaatgtga cagatgctgt gtgtgtaagt aatgacataa
    35521 attctacaaa aaatgctata ttacagtatg gagcagtaac atctggttat tatgaagata
    35581 ttaaatatca aagtgatgac caaaattcat attattgtcc aacaaaaagt tttaatacaa
    35641 atcatgctat ttcaattgta ggttgggatg ataactattc taaagataat tttaatgcaa
    35701 atattagacc atcaaaaaat ggtgcttggt taataaaaaa tagctgggga gattataatt
    35761 ctgagggtgg atatttctgg atatcttatg aagacaagac acttatgtct gatatagata
    35821 atttttcaat caaaggtggt aaaaaaccaa atgatgatga gaagatgtat caacatgact
    35881 atgcaagtat tgtaccttta atttcaaaaa agataacagc tgcaaatgta tttgatttca
    35941 atagaggcga tgaaactcta aaatctgtaa tgttcttaac tgaaagtata ggagctaagt
    36001 atgaagtata ttatgctcca gtagtaaatg gtatacctca agaaaacaat atgaaaaaat
    36061 taaaagaagg tactgcccaa tattcaggat acataacagt tccaattgat tcttttgata
    36121 taccagaagg aaagggtgca attgtagtca gcatagaggg gaaaaatgga gagtcaacta
    36181 taggttctga gtcaaatgta ccaggatatg atacatttaa agcaaaagct aatttaggtg
    36241 aaagttatat catagataat actggaaaat tctttgatat aaatagagat agtaacttct
    36301 atccgtgtaa ttttactata aaagctgtta cagaaaagtc ttctggtgag agtatcccaa
    36361 atgagtcttt aattggtagt gatagatatg aaactgctat caaagttagt caaaatggtt
    36421 tcaattcttc agaaaatgta gttttagtaa atggcagttc aatagtagat gcattggcag
    36481 caactccttt tacatctgct ataaattcac caatattatt gacacaaaaa gaagctttaa
    36541 attcaaaaac taaagctgag atacagagat taggtgctaa gaaagtatac ctaataggcg
    36601 gagaaaattc tataagtaaa gaaattgaac aacaattaaa aagcttaaat atatcgatag
    36661 agagaatatc aggaagtgat agatacaaga caagtttatt attagctcaa aagttaaatg
    36721 gtataaaaaa tgtatctcaa atagcagttg taaatggagt gaaaggatta gctgatgcaa
    36781 ttagtgtagg cgctgcagca gcagaaaata acataccaat catacttgca aatgaaaaga
    36841 gcgaattgca aggagctgat gaatttctaa attcattaaa tatagagaaa tcttatatta
    36901 ttggaggaac agcatcccta tcaaacaatc tagaaagtaa gttaaaaaat ccaactagat
    36961 tatctggtag tagtagagac gaaactaatt caaagataat agataatttt tataaaaaag
    37021 atactttaaa aaatgcattt gtagttaaaa atggaatcaa gaatcaaaat gatttaatag
    37081 atggattggc agttggtcct ttaggagcaa aaactgggtc accagtaatt ttagttggtg
    37141 ataaattagc tgatagccaa aaagaagttc ttaaaaataa gactttagaa aaagtaactc
    37201 aagttggtgg aggagcaaat aaaaatgcat ttaaagagtt agtaaaatta aaaagtgcta
    37261 aatagagtac ttaagtatta acatatatta gtgtgtatta gtaacttatc ttaataaaag
    37321 ctgaaaataa ttacttcaaa ttattgataa ataagataat caatgattgt aaagttttgt
    37381 tttcagcttt aaatttatgt agtataagtt taaaaacata aaaaagggtt actttatata
    37441 gaaatataga aaatcttaca ttttatatat aaataaccca tatttaatta actttttata
    37501 gtgttctaat agatattatt gaacttaatg gtaaatataa tgtgtaagtt tcatttaaag
    37561 ttggattaga ttcatctata tatcttgagc aaagtgtaat tgataagcta tctgcttcta
    37621 taatttcacc atatagagga caactgctaa agtaagaatg tacttcaaca tatttattta
    37681 agttttcttg aacataatcg taaaaacggt tttttgtagt agtagccata aaatcaactc
    37741 ctttattttt tattaaagtt gaaactttta aaaagataaa tatgattact tctattagaa
    37801 actaagttaa aaaataagca aatagatatg aaaattagaa taatatatta tttatatctt
    37861 aattataaca ctagataata aaaaatgcta tataaaattc agaattttcg aaagttttta
    37921 agcttatttt taaatatact aataatacta ttgacattag atagaaaaag tattatatat
    37981 gactatataa attattttag tcaaactgga gggaaaagat gcctaaatca tattctgata
    38041 aagaaagaga gtatataata aaaagactta aagaagaagc aagattgtgt atggagcaat
    38101 atggtattag aaaaactact gttgatgagc ttgtaaaacg ggtaaaaata ccaaaaggaa
    38161 ctttttatct attttttcaa tcaaaagaat tgctcttttt tgaggtatta agagatatac
    38221 atgactctat acaaaaagaa atcttatatg agataaatag agtagatgaa agtattacat
    38281 gtgaacaatt gacagatata tttatgaaat tctataggat ggttgatagt acttcaattt
    38341 taaatctcat gataaatgga gaatttgaga tattggtgag aaagttacca gattctataa
    38401 ttgaagaaca ctttagacat gatgactttg aaattggaga gattatatct tgcataccaa
    38461 atgcaaaaaa taaagacata gaaagcttta gtggagcatt tagagcagtt tttcttacca
    38521 tgctatataa gcgcgaggtt ggaagtaatt gttttgaaga tgctttaaga ttaatgataa
    38581 acggattagt tatacaactt atggaataga atttaaattt tgtttgctaa taacttttat
    38641 taaaaattat taacaaacaa aaaaattata ttttattgac catatagtca aaatagtcaa
    38701 aaatttgaaa gggtgatatt gaatgattaa agttgatgat ttatcattta gttatacaga
    38761 tagagatttt ttacaaaata ttaactttga agtaggaaaa ggggaaatac taggattttt
    38821 aggaccatca ggtgcaggaa aatctacatt acaaaagatt ctaattggaa tgataactaa
    38881 ttatggagga agtgtcattg taaatggagt agagagtaaa agacactcaa ataaatttta
    38941 tgaaaatata ggagttgatt ttgaatttcc tagtttatat gaaaagttga ctgcaataga
    39001 aaatttaaaa tattttgggt ctctatattc taaaaaacta ctatctattg atgagttatt
    39061 aaaatcagta ggactagaaa atgaagcaaa taaaagggta tctgagtatt caaaaggtat
    39121 gaaatctcga ttaaatttta taaaagcttt attacataat ccagatattt tatttttaga
    39181 tgaaccaaca agtggtcttg acccgtcaaa tagcaaggtt atgaaagata taattttatc
    39241 agaaaaatct aaaggtaaaa ctattatttt aacaactcat aacatgttag atgcaacaga
    39301 gctttgtgac agagtagcgt tcattgtaaa tggtaaaata tctgctttag atacaccaca
    39361 taatcttatt atgtcaaaag gagctattaa agttagatat acttactttg ataatggaga
    39421 aaaaacttct gaatgttttc tgaacaatac tgctaatgat aaaaatttga atatgcttat
    39481 tgagaaaaat aaacttttat caatacatag tagtgaacca acattaaatg atatttttat
    39541 tgagataaca gggaggaatt tacaatgagg ctaaaaaatc ttattttagg agatataaag
    39601 tttcaattta agtatggttt ttatttttta tatctttttt taagtattat atatatttgt
    39661 attatcaatg tatttccaac ttttatgaga gaaaaaatag ctataattat gatttattct
    39721 gacccagcag caatgggatt gttttttatg ggagctattg tacttcttga gaaaagtcaa
    39781 agggttttaa attccttagc tgtatctcca gtaaaagtat ctgagtatat tttatcaaag
    39841 gtaatttcat taggagtaat atctagtatt gtagctatgt ttattgctat tacattaaat
    39901 ttagataata ttataatatc aactataggt accttttttt cttctattat attttctttg
    39961 cttggattga taattgcaag taaagcatct agtttgaatc agtttattgt tttaagtatt
    40021 cctattgaga ttatatgctt tattccacca atactgaatg tacttcttga cacaaaatca
    40081 tatgcaaatt tgtacccttt taatatatgt atttctctta ttagtggaaa taaaaatttt
    40141 ataatgatta atattttaat tttaatatca attataataa taatttattt tataacttat
    40201 tattttattt gtagcagttg gaaaaaggta ggtggagtaa aactatgata aagattataa
    40261 atgcgtttaa acaagagttt gaacaaatta agagagatgc tatgcttttt atagtatgtg
    40321 tttctccaat attatgtgga gtatttataa aatttggaat accattaata cagaatatat
    40381 cacttaacaa gttttattat caattaaatt tagagccgta tttcttgatg tttgatttac
    40441 ttttagcttt tattacacct tttatgttct tttttgcttc tacaatggtc atattgggag
    40501 aaattgatga cagcatttca agatatttaa tagtaactcc gcttggtaaa actggttatc
    40561 ttatttcacg atttggaata ccaggtatct tagcatttgt tattactatg attctactta
    40621 tctttttttc tctaactaaa atttctttct tgttaaactt atcaatttct ttattagttt
    40681 tattacaagg aattattata tcaatattag tgatttcttt atcatcaaat aaactagaag
    40741 gaatggtaat tacgaaattc tcaggtgttt ttatgatggg tattttagca ccatttttta
    40801 ttttaaataa agcacaatat attctgttct tcttaccaac tttttggata tcgaaggcat
    40861 ttaaggaaga taattatatc tatatgttta tttcaattgt tatatcatta atatggattt
    40921 tattattatt taaaaagttt agtaaaaaaa tagttaaata agaaaattta atatataaat
    40981 gtaaggttaa cttgacagta atgttgaaaa atgttacatt taaaatgtaa agttaacctt
    41041 acatgaatgg agcaaatatg aaaaataaaa taaagatatt aagagaaaaa ttaggattga
    41101 cacaagaaca actaggaaga ttagttggaa catctagaca ggctataaat gctatagaaa
    41161 ctggtaaaaa tgaaccttca atatggttgg catatgatat ttcaagaatt tttaatgaac
    41221 caattgaaag tgtattttta tttgaagaaa gtgaaagaaa atcaagagca cagataagta
    41281 ggggagaata ttatggctat aagaaagata agaacatttg atgatgaaat tttaagaaaa
    41341 aagagtaagt atgtagaaaa cgtagataat aagataagag aaatattaaa tgacatggca
    41401 gagaccatgt acaatactcc aaatggagga ggattagctg catgccaagt aggagtatta
    41461 aagcgattag ttgttataga tttaggagaa ggacttatta agcttgttaa tcctgaaatt
    41521 attaaacaag aaggggaaca aattgttgtt gaaggatgtt taagttttcc tgaagtatgg
    41581 ggtaaattaa aaagaccaaa aaaagttaca gtgcaagctc taaacgaata cggtgagaaa
    41641 atagaaatta aaggttcagg ttttatggca aaatgtcttt gtcatgagat agaccattta
    41701 aatggtatag tttttacaga taaaattatt gaacatgtaa aattgtaaga tagattggtt
    41761 attgaattta taaaatattt tatagtaagg agttaaatta tgagattatg gcataaggat
    41821 ttaattgatg tattacctaa aaatcaatta gtaagtcaat ggagagagct acttgctata
    41881 aaaggttcta tagataaaaa aggtactcca aaccatgtat tagtgaataa agtattgaat
    41941 tatagtatag atgaatttaa attttataca aaaattgtac atgatgaaat gttaaaaaga
    42001 aattataaac ctaatgaact taaatataca agtatattaa aatggaaaaa tagaaatttt
    42061 gcaaatgata tatctaatga acatagttta aatttagaaa atttatatga tgattggcat
    42121 aataaaatgt atttaaagca atgcttatat aatttagaag aaaaagcaac atgtggagga
    42181 ataccaataa atgaatggaa tatattactt tgtaaatata gtaaagatta tgaattgtgg
    42241 tctggaaata tcatgtttta attactatag attaacatta tagtattatt gtatataaag
    42301 aggtgattat ttgtataata aaataaaata tattccaata aattgtgaaa tagcttgtaa
    42361 taaattaaaa aggagtatgc catataaatg ggatttaaat atttatcgtg gatgtgagca
    42421 tggatgtaaa tattgttatg ctatttactc tcataagtac atcaactcca ataattattt
    42481 tgaagagatt tatgtaaaaa caaatatagt agaaaaactt gagagacaac ttaaaagcag
    42541 taaatggaag aaagaagtaa tcaatatagg aggagttaca gatagttatc aaccaataga
    42601 agctgactat aaaattatgc cagaaatatt aaacctgcta ataaaataca agacaccagc
    42661 tattatttct acaaagtcag atttaatttt aagagattac gatttaattg ataagctatc
    42721 taggattaca tatatcaatg tagcatctac aattaccaca gtaaatgaag atacacaaag
    42781 gcttattgag ccaaatggtg tggattcaat gagacgattt aaaatgttaa aagaatttag
    42841 aaaaactaac gcatcagttg gtctacatat tatgccaatt ataccatata ttacagatga
    42901 ttttgataat ataaattcgc tatttagaca tgcaaaagaa tgtaatgtac attatgtttt
    42961 acctgggact ttatacttaa ggggtataac tagaggtgtt ttttttgact ttgttaaaaa
    43021 agagtttcct gaattatttg ataaattatc aatactatat agtgcaggtt cacttaatag
    43081 ggagtataaa aatcaattgt ataaaatggt taatgaactt agatataagt attctctatc
    43141 aagcagttac tctaaaataa tgaaggaaaa gttaaaaaac tcaggagatg tacagatatc
    43201 tttttttgat tagttttata taaaaaaatt tttt
//
LOCUS       DAFAZV010000034        43024 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFAZV010000034 DAFAZV010000000
VERSION     DAFAZV010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 43024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43024
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.034"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            32..1144
                     /locus_tag="KOU88_002558"
     CDS             32..1144
                     /locus_tag="KOU88_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5009 domain-containing protein"
                     /protein_id="HBK3212429.1"
                     /translation="MNSRIKSIDIIRGLSIALMIVCNNPGTWMRMYPQLRHAVWHGVT
                     LADFAFPFFVISLGVTIPISINSKIKNNKSTLSIILSISKRSILLILFGFFLNYLGNP
                     DLDTVRILGVLQRMGLVYFVTSLVYLLLKKLNVGSTATIITFLCISTFIIVGYYILAK
                     PYGFELEGSLAQLVDLHFFKGHLYKPEFEPDGFLTSIVAISSGMLGCTMGCVLLKEDI
                     GEYKKFFKILVMSIILLIGAFIFNQYFPFNKRLWSSSFVLLMAGSYGVLLSIFYFICD
                     IKNKSKIFTPIIALGSSPIFTYMCLEILSHVFWNVPKLTNKVDYPTTLVEWTTYELIT
                     PWAGTTWDSLVFSLLYVLFWIIVMSIMYKKKIFIKI"
     gene            1398..3422
                     /locus_tag="KOU88_002559"
     CDS             1398..3422
                     /locus_tag="KOU88_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3212430.1"
                     /translation="MKKTTKLLATGMLSVAMVAPNVALAAENTTANTESNSDININLQ
                     RKSVVLGSKSNASVKFKEKLNADSITLNFMCYDMPLEATLNYNEKTDSYEGVINYNKD
                     PEYLNVWELQSIKINGKDEQKVLNKEDLESMGLNLKDYDVTQEFIISDANSTKAVNEY
                     MRKTSAPVKKLAGATRFETAVEISKQGWKDGSSKVVIVNGELAADGITATPLASTYDA
                     PILLANKDDIPESTKAELKRLNPSDVIIIGDDGSVSQKAVSQIKSAVNVNVTRIGGVD
                     RHETSLLIAKEIDKYHDVNKIYIANGYAGEYDALNISSKAGEDQQPIILANKDSVPQG
                     TYNWLSSQGLEEAYYIGGSQSLSSKLIDQISKIAKNGTSKNRVSGADRHETNANVIKN
                     FYPDKELSAMLVAKSDIIVDSITAGPLAAKLKAPILITPKTYVSAYHNTNLSEKTAET
                     VYQIGDGMKDSVINSIASSLSKHNAPTEPDNSGSAAGKTVVIDPGHGGSDSGATSGLN
                     GGAQEKKYTLNTALATTEYLRSKGINVVMTRDTDKTMALGERTALSNTIKPDLFTSIH
                     YNASNGSGNGVEIYYKVKDKNGGTTKTAASNILKRILEKFNMKNRGIKTRTLDNGKDY
                     LYVLRNNNYPAILVECAFIDNKSDMDKLNTAEKVKTMGTQIGIGIEDTVK"
     gene            3642..4328
                     /locus_tag="KOU88_002560"
     CDS             3642..4328
                     /locus_tag="KOU88_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBK3212431.1"
                     /translation="MSGYTNDECEIPKIKSYPGADKEIASEIDYSIVKGTVLFDLYQR
                     IMDLVLSIIGLVIGLPLIAIFGILIKIEDKGPITYKQERLGKCGRRFYIYKLRSMRTD
                     AEKFGAQWAEKDDPRITKVGKFIRKTRIDEIPQLFNILKGDMGLIGPRPERPNFTVQF
                     NEEIPGFINRLAIKPGLTGWAQVNGGYEITPEEKLKEDIYYIKNRSILLDFKILFKTV
                     KVVLTGDGAR"
     gene            4423..5478
                     /locus_tag="KOU88_002561"
     CDS             4423..5478
                     /locus_tag="KOU88_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp7"
                     /protein_id="HBK3212432.1"
                     /translation="MIKKISTILSLVLLISISSTIGVFADANPKRELIEGSIPEISTE
                     LNKRAFKDSKEVILVNEESIVDSISATPLAYAKNAPIVVTKSKNLGRVTRNYLKELGP
                     EKVTIVGGLKAISKDAERNIEKMGMKVERIRGKDRYDTSLKIAREMYRTVGFDEAFLL
                     SSTTGLENAISVYSYAAKSGMPIIWAKDEGFEEQIDFLKGKNLKKIYALGDSKEFIAE
                     IDSNLKNIEGIKQINKSSTNVDLIKKFYDEKDIKKIYTARLDFGSRSDVNEYISLGVV
                     SAKENMPILICSDNLSRAQDKFLKDSNINDVVEVGYTVGDYSLFRSIFNLTFLSCIVL
                     ILLLLLITFRALRYESK"
     gene            5593..7149
                     /gene="murJ"
                     /locus_tag="KOU88_002562"
     CDS             5593..7149
                     /gene="murJ"
                     /locus_tag="KOU88_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBK3212433.1"
                     /translation="MSKTAKAALWIMAATMFSKVLGFLRELVLANFYGTGMYADVFVL
                     TLNIPGLIIAVIGSAVATTYIPMYFETKKRLGDEGALKFTNNVLNICYIMAIVIAIIG
                     LLFTEQFVTVFAAGFRNDPAKFQAAILFTKIMISGVLFLSGSKIFSSFLQVNDSFVIP
                     GLIGIPYNIIIIAAIALSAGKNVWILPAGALLAMASQLLFQLPFAFKKSYKYKPYINL
                     KDESIKELVNLVLPMLVGVAVGQLNIFVDRLLATTLGNGKLSALNYANRLNEFVMALF
                     VTSIITVIYPKLAKMSGKDNKEGFISTIVKSSNCIILVVLPISIGAIILAEPLVRILF
                     QRGKFDALSTDLTSIALRLYSLGLLACGVRDVLYRAFYSLSDTKTPMINGSIALIINI
                     VLNLILIRPLGHAGIAISTSTSNIITVILLFISLKKKNGYFGGDKIIKTGLKSLVASG
                     VMAVATLLIYNNLYAFMGSGTIKEIISVGAGVLGGASVYTVLIVLFKVEEMDLAFEFL
                     RKGKQKLLRR"
     gene            7195..8901
                     /locus_tag="KOU88_002563"
     CDS             7195..8901
                     /locus_tag="KOU88_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBK3212434.1"
                     /translation="MDYKNNYEMWLNSPYFDEQTKNELLSIKDDEKEIQDRFYKNLEF
                     GTGGLRGIIGAGTNRINIYTVRRATLGVLNYIMKTQGEEGKQKGIVIAHDSRYMSREF
                     CIEVAKTLSAYGVKAYIFEELKPTPELSFAVRYLKCAMGIVITASHNPKEYNGYKVYD
                     SDGGQICIDMANDIIAEVNKIDDYSIIKSIDFEEALSKNLITILDNEVDDEFIKAVKK
                     QVLRQNIIDECGKKLKIIYTPIHGTGNKPVRKVLNECGFENVMVVKEQELPDSNFSTV
                     KYPNPEEKSVFNIAIEMAKNNGTDLIIGTDPDCDRVGIVVKDSSGEYVVLNGNQVGSL
                     LVRYILESLVEENKLPKNNPTIIKTIVTSELGAKIAKAYNVDCLNTLTGFKFIGEKIK
                     AFEESNDRSFIMGYEESYGYLIGTHARDKDGVVSSLMICEMAAYYSSKGMNLYEALID
                     TYNKFGYYKEDLKSVTLKGIDGIKKIKEMMLYFRSVKIDNVADVKVDKILDYKDGVDD
                     LPKSDVLKFLLEDGSWIAIRPSGTEPKIKFYFGANSDNQEDVEFKLNNLISYILNVVD
                     SI"
     gene            8923..9996
                     /locus_tag="KOU88_002564"
     CDS             8923..9996
                     /locus_tag="KOU88_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="HBK3212435.1"
                     /translation="MKVYNVIMAGGGGTRFWPLSRQEVPKQLINLSGEDALINETINR
                     IDSLAKKDDLFIVTNEKQLEALKDIVKDKCLDSNILPEPCARNTAAAIGFAAFNIMKK
                     YGDGVMCVYPADHYIKDEKEFKSILEKAIYIAENNDKLVTIGITPTFPSTGYGYINFN
                     RENTIEDVAYEVVEFVEKPNYEIAKEYVNSKKYVWNSGMFVWKVSKILEDFKRYLPKV
                     YEKLEDISKYLGTKEEMEKIKEIYPTIQSISIDYGIMERSNDVIVVPGDFGWNDVGSW
                     DSLGAIYPTDDEGNIKRGENITIDTKNSIIYSDDKLISTIGISDLIVVSTNDAVMVCR
                     KDKAQDVKKIVEQLKEEDRQEYM"
     gene            10008..10730
                     /locus_tag="KOU88_002565"
     CDS             10008..10730
                     /locus_tag="KOU88_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK3212436.1"
                     /translation="MIPKKIHYVWFGGPKGNIENICINSWKEKLPEYEIVEWNEKNFD
                     IEKEIKGNKFLEECYKRKLWAFISDYTRIKVLYEQGGVYMDTDMQILKDITPLLENNR
                     LICGYEDDREYINGAIIGVEKGHPFLKDLLEYYEKEVLTSSLFTIPKIMTHLMEKNYK
                     KIDPNNYEEGIRVYDKEYFYPFGFKEDFTPECITENTFGIHWWGKSWAKKRNYFLESK
                     HLTGVNKIWKCCKIFASNTLRS"
     gene            10746..11903
                     /locus_tag="KOU88_002566"
     CDS             10746..11903
                     /locus_tag="KOU88_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide polymerase"
                     /protein_id="HBK3212437.1"
                     /translation="MKTLNDDRNIMIRKYLYIFVLFIILLRKYMISFIDPNMDIGMIK
                     SALFYSSIGILMLLFLFDKRKSITEMVLVGVCVLLYLLNREGAILLIVLLAVSAKQID
                     DKFIVKNYLIISACFLMVAILLFNLFPSLIFNQEVHYRYIEKIDMLVTRMDFGLGNPN
                     SVFYHMVTIYAAYIFLRYKDYNKWDRIILFGSAFFVYQTTYSRTGFFTILAGLIFVEI
                     IRWIDIKKIKGLPMLLKTLPIILTLFSVIIGTVFDKSTLLNRLLASRPKFWHVYLAEK
                     GNFLKPFGNSYSPAIKATNPLDSSYVYIISVLGVVACILFMYLMYKGIESFIEKDKKA
                     YLVALFIFLLYSFAENLLLEASFSFAVVLLIKEVILNDKREIDLWKMKSRR"
     gene            11906..12745
                     /locus_tag="KOU88_002567"
     CDS             11906..12745
                     /locus_tag="KOU88_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3212438.1"
                     /translation="MLISLIMPTLNRYDDIYLLMDSLENQTYKNFELIVVDQNDNSKV
                     KEIVDKYIDKLDIKYIKSSKKGLSYNRNVGIDNAVGQIIGFPDDDCVYENDTLEKVIN
                     FFNKNKDYKIYSCKTMDSNKVDAFKKMYDGTCDITSSNVLDTITSITFFIDFEGKDYT
                     RFDEKLGVGGEFGAGEEIDYVLNLLSLGFKGKYFGNDIIYHPAKKHSKSKEKYQKDYN
                     YGRGFGALCKKEIVYRKNYKFAKVMVSKLVRNIGGLILSSNRDYHSATIKGRINGFRQ
                     YKL"
     gene            12760..13935
                     /locus_tag="KOU88_002568"
     CDS             12760..13935
                     /locus_tag="KOU88_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HBK3212439.1"
                     /translation="MDKVKFLINMLLAFFIYPFNKHKFNGRDIWLIGGHSGDIYNDNS
                     KFFYEYMLKEHNDVETYWVVNKDSKVFDKIPGKKLIRGSVENYLYYYNSKAIVFSHAP
                     SADIAPYNFAVPVLNYFHKKTIKVFLNHGTISFKKRKPMNKKFKNIIDNLYKSYNIVT
                     ASSEFERNVMVNDWGMLDDSVYIIGNARYDNLPTNEVAQTRDILYTPTWRDWIKFSSG
                     KFTDTDYFKNIMNFLNDDKLNKILDEKDINVKIYMHHLMHEFIDDIKENITGKRIVFL
                     DKGVTLANEIRKSAANITDYSSVAIDFLYMNRPILFYQFDLDEYMEKVDSYIDLKSEM
                     FGSLAYNNDEAVNKLIDIIENNFEVMDNQKNERNKFFRYNDNKNCKRIYDCVLSKIK"
     gene            13964..14713
                     /locus_tag="KOU88_002569"
     CDS             13964..14713
                     /locus_tag="KOU88_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3212440.1"
                     /translation="MKKNLVSIITPMYNSEKFIEATIKSVLNQTYQEWEMLIIDDCST
                     DNSPNIVKSYMQQDSRIKCIKTETNKGVSNARNLALSKATGQFIAFLDSDDQWNSSKL
                     EKQVNFMLENDYVISFTSYELMDENDKKLNKVIKVPPNVDYRRLLKGNILGCLTVVID
                     KSKLDFEIRMSGVRHEDYVLWLSILKKGHIAHGINEVLALYRKSSNSLSGNKIKAAMW
                     TWNIYRNIEKIPLYKAIYYFINYGINGIKKS"
     gene            14735..15643
                     /locus_tag="KOU88_002570"
     CDS             14735..15643
                     /locus_tag="KOU88_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3212441.1"
                     /translation="MYKYKFTVFTPTYNRAHLLENLYNDLKAQTYDFNDFEWLIVDDG
                     SSDSTKELVEKFISENKLNIRYIYKENGGKHTAINLGVKNADGELFFIVDSDDGLIKD
                     SLEIANDEWDSLENKEGFSGVVGLCVYPSGDLIGTEMPEDKKICHFADLYFKYGVKGD
                     KSIVFVTDELIKFPFPERKEVRFLPESVVWNEMSKYYKVICVNKPMIIRDYLDDGLTK
                     NILSKNALRGRALEFLYLINQNTYPLSRYPYMWIKNYINLARYSLLSDSHYFGELRKV
                     SDKLLYLALFPLGYYKYIGQRKLVSK"
     gene            15691..16443
                     /locus_tag="KOU88_002571"
     CDS             15691..16443
                     /locus_tag="KOU88_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3212442.1"
                     /translation="MNEPLVSIITPVYNSEEFLSETIKSIQNQTYKNWQLLLVDDCSK
                     DNSSEIIKSFRKEDARIKYIKLEKNSGAAVSRNVGIKNAEGRFIAFVDSDDLWDSRKL
                     EIQIEYMLKENVGFSFTSYRYMRQDGSKTNKVARAPKKIDYEGLLRNTIIGCSTVVID
                     KEIVGEFSMPLVRRGQDTATWLQLLKKEKYAYGIQEDLVNYRLVGNSISSNKIKALKR
                     TWNTYRNVENLSLPKSLYVFCFYVFNAIKKRV"
     gene            16397..17764
                     /locus_tag="KOU88_002572"
     CDS             16397..17764
                     /locus_tag="KOU88_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose/GDP-mannose dehydrogenase family
                     protein"
                     /protein_id="HBK3212443.1"
                     /translation="MYFVSMFLMPLKKEYKFYILGGKKMKIAIAGTGYVGLVTGVCLA
                     EVGNENVVCVDVDEQKVKSMKLGIAPIYEEGLEELMVKNYNRGRIDYTTDYKKAYEDV
                     DVILIAVGTPERSDGSANLDYIKAVAKQIAETVTKDTLVVIKSTVPIGTNEEIEDYIN
                     RNLKNDVKVELASNPEFLSQGTAVKDTLHASRIVIGVESEWAREILEEIYKPFNQPII
                     VTNRNSAEMIKYASNNFLALKISFMNDIANLCEIAGANIEDVALGMSYDDRIGSKFLK
                     AGIGYGGSCFPKDTKALHWLSEHNGYELKTVKAAIEVNESQKLKLVRKASKLVESFQD
                     MKVAVLGLTFKPDTDDIREAPSIPNIKYLLERGARVTVYDPIGVNNTKKIFGDSILYA
                     DSVDDAIEDAEICFIMTEWKDVLNYDIHKYKEKMKNPLVLDGRNCYKIKDMEELGIEY
                     YSIGR"
     gene            17770..18861
                     /locus_tag="KOU88_002573"
     CDS             17770..18861
                     /locus_tag="KOU88_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK3212444.1"
                     /translation="MKTVCYLADGSNPHTLKWCSFFKNKGYDIHVISLNGGHMEGIKI
                     YNFGSNVEELKNENISKKTGYLGSIKQIKKLVNEIKPDILHAQYASSYGFIGSLLGYH
                     PYIISVWGTDIYDFPNNGFIQKQIIKHNFRKADYIFSNSRDMAKEANKYTAKHVDVTF
                     FGVDMDRFKPMEVEKEDAFVIGIIKSLEKKYGIEYLIQAFKMLKDEYKDKKIILKIGG
                     SGSQMDNLINLAKELGIENDVQFLGRISPENVSKTFNSFDVTVFPSLREGFGVAAIES
                     EACEVPVIVTNVGGHPESVWENETGLIVEPKQPEEIKNAIIKLMENDELRLNMGKKGR
                     QFVRENYEVNLNFNDIEKIYDSIFDKYKK"
     gene            18945..20858
                     /locus_tag="KOU88_002574"
     CDS             18945..20858
                     /locus_tag="KOU88_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK3212445.1"
                     /translation="MRESIDLEKESFFNRLFKKYKFRHLTLLILDICSVLVAFRMSLS
                     LTGNLNAFTTNDIIISACIYIVLHIVSFRLFKCYNTLWRYAGEEEIISIFMATLAYLI
                     PIYIINKLLGFDYPIMFYVLNTIFIIMFTSGARIAYRAIRIVMNKTYSRGKVSNILII
                     GAGDAGEMVIQELKRNPELKKVAVAIIDDDKNKIGRIIHNVKIVGTTSDIKDVVEKYN
                     VDEIIFSIANIEKRRKKEIIDICKNTNCKIKTIPGIYEIIDGKVDIKQIREVEIEDLL
                     GREPIKTNLREISNYIEGKVILITGGGGSIGSELCRQIAGFNPKELIIVDNYENNAYS
                     IQQELLRKYKNKLDLKTVIASIREEKRMDEIFNKYKPEVVFHAAAHKHVPLMESSPGE
                     AIKNNIFGTLNIAGLSSKYRAKKFVLISTDKAVNPTNIMGATKRAAEMIIQTMNAESQ
                     TEFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTHPDIIRYFMTIPEAVGLVIQAGA
                     MAKGGEIFVLDMGEPVRILDLAKNLIKFSGFEPDVDIKIEFSGLRPGEKLYEELLMSE
                     EGLLDTEHKKIFIGRPIDVDREKITKYLKLLREITNNEEVEKIDGIMRELVPTYIKPE
                     DANIKEIATTREK"
     gene            21057..21764
                     /locus_tag="KOU88_002575"
     CDS             21057..21764
                     /locus_tag="KOU88_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK3212446.1"
                     /translation="MMNIKNKKHILKKFIAMVLIAGVVTVEAGAITASAAEPTNSPMS
                     ATVDQCDFLNVRSGASANDAVVGKINTGDKVEVLELHSNGWIKIKSVDNVTGWVNGDY
                     LTIQGGNVDAKVQNVLNLAFKQQGKPYKWGATGPNSFDCSGFTSYVYKNGAGVNLPRV
                     SRSQATVGKKVSRAELKPGDLVFFGSGGSINHVGLYVGDSKFIHSPQTGDVVKVTSMA
                     PGTNYAKRLITATRVLQ"
     gene            22065..24176
                     /locus_tag="KOU88_002576"
     CDS             22065..24176
                     /locus_tag="KOU88_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding glycosyl-hydrolase Cwp19"
                     /protein_id="HBK3212447.1"
                     /translation="MKKISILVLSLIMTLTMCSVSSFADSSNDKEMRAAWISTVYNLD
                     WPKTKNNEAKQKKEYTDLLDKLKSVGINTAVVQVRPKSDALYKSNINPWSEYLTGTQG
                     KDPGYDPLPFLIEEAHKRGMEFHAWFNPYRITMADESIDKLPANHPAKKNPSWVVKHG
                     NKYYYDPGLPEVRKYIVDSIAEVVQNYDIDGVHFDDYFYPGVSFNDTATYQKYGKGQN
                     KDNWRRENVNTLLRDVKASIKSIKPNVVFGVSPAGIWRNKSSDPTGSDTSGNESYVGT
                     YADTRAWIKQGLIDYVVPQLYWPIGLKAADYSKLVAWWANEVKGTNVDLYIGQGIYKQ
                     GQSSYGGQNIAKEIVQQVTLNRKYSEIKGSMYFSAKDIANSTSIQKDLKSLYSSSEEP
                     VTPPSNVKVEKLRGDERYDTAVAISKKGWATNSDTVVLVNGYSIVDGITSTPLATSND
                     APILLVNKDNIPTSTKNELKRLNPSKVILIGGNNSIGDKVESEIKDTLSNVSINRVGG
                     SDRYSTSLMIAKELVKTNPVEKLYITSGTGEADSLSIASKAGEEKQPIVLVSKDNVSD
                     EVYNWISDLKVKDAYFIGGNLSISDSVINKLDKVITNDVSKNRIAGENREETNGKVIQ
                     KFYPNAEYSSMFVSKSNQLVDALTSGPLAAKLKSPVVMLGNSVTSAQKTALEPKKTTL
                     VYEAGDGINQNTLNTFLNLVK"
     gene            complement(24374..25339)
                     /locus_tag="KOU88_002577"
     CDS             complement(24374..25339)
                     /locus_tag="KOU88_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK3212448.1"
                     /translation="MSKLKKFVILLAFLVVIFPISVYGYFYYKLSAIHDSSISSDLLD
                     NNDHKNEDGIINILLMGTDARPNEDSSRSDAMMILTIDNKHNDIKLTSLARDSYVDIP
                     GHGKQKLTHAYAYGQADLLIQTIEENFNIDIQNYACVNFESFMYIIDAIGGVEVTVEK
                     GEIRELNKFIPETYKWNKSDDKGSIQYIRNSGKQTLNGYQALSFARIRHNDTAFARDG
                     RQRQIIQAIIKKTETLPVTKYPGLLDAVLPYVKTNMKPNAILSLGAQVLKMGDLNIKQ
                     FEFPIDDEIHSTGGIYGKAGWVLRFDPDTLDILHDFIFNDIEFKQ"
     gene            complement(25624..26580)
                     /locus_tag="KOU88_002578"
     CDS             complement(25624..26580)
                     /locus_tag="KOU88_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK3212449.1"
                     /translation="MSGLKKFVIFLALLVIAFPVSIYGYVFTKLKTIQDDSINTEALS
                     SNDYKNEENITNILLLGTDARPGEEVSRSDAMMILTIDNKNKSLKLTSLNRDTYVNIP
                     GRGEQKLTHAYVYGQANLLIETIEENFQLDIQNYAVVDFFSFMDIVDALGGVTVTVDK
                     SEIRELNKFIPETYKWNKNDNKGSLKYIRNSGEQKLNGYQTLAFSRIRKNDSTDERDR
                     RQRSVIQSLINGVKDLPVTKYPNLVNTILPYVKTNMNPNEIISLGKELLSIGNLNLKS
                     MEFPLSTENGRKIGNAGYVIPFEEYELDAMHDFIFKDIMVED"
     gene            26948..27736
                     /locus_tag="KOU88_002579"
     CDS             26948..27736
                     /locus_tag="KOU88_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK3212450.1"
                     /translation="MIKLIATDLDGTLLDEKSEINPEFYKVFKKLRERGIMFSAASGR
                     QYQNLIKKFEDIKDDMMFISENGTLVVYKGKEILSNPLNKELVNEIIETTRSIKGKKI
                     VMSGKKYAYIESKDEAFIQEVSTYYAKFKIVEDLTKVEGDILKIAVFDFKGAEHNNNI
                     YFEKFSDRAQVCISGVEWLDLTAKGANKGSAIKKVQKMLDIKYEETMVFGDQLNDVEM
                     MKSAYHSYAMENANEHLKQIARFRAKRNTENGVVDKIKEVIKIG"
     gene            complement(27859..28329)
                     /locus_tag="KOU88_002580"
     CDS             complement(27859..28329)
                     /locus_tag="KOU88_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4358 domain-containing protein"
                     /protein_id="HBK3212451.1"
                     /translation="MKKILILFFSIILSLGMVSCSSSGDYKNVSTSKIKKALKSSDLL
                     IKESKIFDAKDFNYFNDVEEDIIQGFVINSSEKLSLEDIIVIKTDEVDKIYKTLENYK
                     KDMIQAPFGEGHGEKINSEIANNTIIEKAGRYVYLISAENATQIENKILNIIKK"
     gene            28468..29112
                     /gene="uppS"
                     /locus_tag="KOU88_002581"
     CDS             28468..29112
                     /gene="uppS"
                     /locus_tag="KOU88_002581"
                     /EC_number="2.5.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="di-trans,poly-cis-decaprenylcistransferase"
                     /protein_id="HBK3212452.1"
                     /translation="MRIPKHVGIIPDGNRRWASQNGMTKDKGYESGIDPGLESYRLCR
                     DLGCEEVTFYGFTTDNTRRPSVQTKAFTKACIDAANILIDEGAALLVVGNTKSPMFPE
                     ELLPYTNRIKAKEGQIKANLLVNYGWYWDLNNISGVENVNKNNIQDYIQSFDVSRLDL
                     IIRWGGRRRLSGFLPVQSIYADFYVIDNYWPDFKSDDIKDAFSWYDTQDVTLGG"
     gene            29155..30060
                     /locus_tag="KOU88_002582"
     CDS             29155..30060
                     /locus_tag="KOU88_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3212453.1"
                     /translation="MKKKLLDGKITLIICKSVKIYTKKGEEMSKGNNNNNSRNKSKKT
                     SHLNRKKRKLNKKKLAVLICFTVLFLFIAFKATQGVVALVKSMDKSNKTNQQQNVNSE
                     QFDLGNEEENKKKKYTVFIDPGHGGNDKGTESKTSNRYEKDLNLQIAKKLANKLSKQK
                     DIQVVVSRTDDTYISLKDRAILANNSSADVLVSIHLNAEKNGNTATGIETWYRNKATD
                     GSKELAQTVQSTIVSYVKVRDRGIVENNFEVLRESNMPAILIECGFLTTPSEEQKIIN
                     EKYQDQLAEGIVQGVLSYLDSKGNK"
     gene            30375..31922
                     /locus_tag="KOU88_002583"
     CDS             30375..31922
                     /locus_tag="KOU88_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009906093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3212454.1"
                     /translation="MNKNSMTRIYSLNKIIFIIIGILGIVLLTRHIEVDIKVLILILL
                     TLFSINVFISYLKIKLYEDKINLGLINNSDKFINITKDENFLKHVQNYIISNEKENCV
                     MACFDLCRLKLINDIYGYELGDEVLNNILSNLKNYFGKEAIYGKLKSDVFVLIIKLEN
                     REQKIPYLVNLIKNKIVILSQIDSFKMDINIEASIGIYKFNNNEIDIKKAIDNADMAR
                     LKSKGLKHIEYVEFDNAMEEEIQSIMKIERDLFLAIKNKEFVIHYQPKVDSSTGNIIG
                     SEALIRWLHPSLGMVGPNKFIPIAEKNGLINNIGRWLIQEVFITINKWISEGINVLPV
                     SINLSRVELYKNDLVDFFKLMFNTYNIPKELIELEITETTALRDVKFISERLYEIKSL
                     GMNISLDDFGVGNSNFINLKGIPLDIIKIDRSLILDIVTNTKTKFMVKAIVNLSHDLN
                     VTVICEGVEDMHQVKVLSELGCNFIQGYVFFKPLDEMNYKKLLTDGSYINLKDTLLDK
                     CMTVEEE"
     gene            31925..32323
                     /locus_tag="KOU88_002584"
     CDS             31925..32323
                     /locus_tag="KOU88_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBK3212455.1"
                     /translation="MISEDVDYSIRIIRAIFNNGEDKPIDAKMILKSEDIPILTLYRL
                     LRKLCANNILTFNKEDGKTYMLNVSLDTISLRTIVEVIDGKIYINKCTRYVSNCSNCL
                     KGCKVNRELLEIEKEIYKLLSRKSIRQILE"
     gene            32363..34096
                     /locus_tag="KOU88_002585"
     CDS             32363..34096
                     /locus_tag="KOU88_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HBK3212456.1"
                     /translation="MDDISQDNFLLSKEYENSLDVDTKKASGIYYTPKIIVDYIVKKT
                     LKNHDIIKNPYPRILDISCGCGNFLLEVYDILYDLFEENIYELKKKYDENYWTVDNIH
                     RHILNYCIYGADIDEKAISILKDSLTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFD
                     YIVGNPPYIGHKKLEKKYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVIT
                     PRYFLESLSGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
                     VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETFYNKIQEKC
                     KYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCWIKSKNINKYIVDKSEY
                     RLIYSNDIDNENTNKRILDEIIGLYKTKLENRRECKSGIRKWYELQWGREKLFFERKK
                     IMYPYKSNENRFAIDYDNNFSSADVYSFFIKEEYLDKFSYEYLVGILNSSVYDKYFKI
                     TAKKMSKNIYDYYPNKVMKIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIK
                     MDNLIMDSLGI"
     gene            34328..35539
                     /locus_tag="KOU88_002586"
     CDS             34328..35539
                     /locus_tag="KOU88_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBK3212457.1"
                     /translation="MKGLVLEGGGTKGAYQIGAYKALRELGIEFQGVTGTSIGALNGA
                     YIIQNDIEVMEDIWLNYDYTHFMNIDRETYERFKNVDFTTKNLNAVFELINKARKNEG
                     IDISPLRQLMETTLNEDIIRKSKKDFGLVTVWWDKKINPYPLYIEDIPKGRLIDYLIA
                     SSSLPIFQTNMMDDKLYLDGMFCDNMPIGLLEDKGYEDVVVIRLIDDFIGKMNLNRHQ
                     NINIKTIIPSEYLGGSLNKDRDNVEKNIRLGYLDTMKAYERCTGIKYYFDVEYKYNEE
                     YCFDKFRSMSNETIQYICNLLNIKRDASLRTVMESVIPKLGEVLGLPKDFSYKDLFYC
                     IYEKKLEENNINRIKLYDFNKVIDVVNTNIDSNRNLASNFEVRPKISIKKNKNTKLLT
                     NCIIKDIKNQS"
     gene            35732..35992
                     /locus_tag="KOU88_002587"
     CDS             35732..35992
                     /locus_tag="KOU88_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HBK3212458.1"
                     /translation="MEKVVSIKNASGLHARPAGMFVKKAAEFKSTVEVVAKDKTVNAK
                     SIMGIMSLGLAQGEELKLVVNGEDEEVALAAMVELVESGFGE"
     gene            36346..38058
                     /gene="ptsP"
                     /locus_tag="KOU88_002588"
     CDS             36346..38058
                     /gene="ptsP"
                     /locus_tag="KOU88_002588"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBK3212459.1"
                     /translation="MAYKGIGASPGVALGKALVVEHSELVIEKKSIDNVEAEIAKLED
                     AVAVSKEELVKVKEKASEELGAEEAEIFEAHLLVLEDPELIGSAIDKIKTESVNAEYA
                     LNEIKEMFVSMFESMDNEYMKERAADIKDVTNRILRHILGIKVVDLSALSEEVVLIAH
                     DLTPSDTATMNKKMVLGFLTDIGGRTSHTAIMSRTLEIAAIVGLNDITSKVKDGDFVV
                     FNGDTGEVIVNPDEETINKYTELKAKYEDERKALQLLKGKPSVTLDGKHVELAGNIGT
                     PNDIEGLIKNDAEGVGLYRTEFLYMDRDSFPTEEIQYEAYKAVLEGMDGKPIVIRTLD
                     IGGDKELSYLSMEPEMNPFLGYRAIRLCLDRKDIFKTQLRALYRASVHGRLRIMFPMI
                     SSLEELLQAKEVVKEVLAELDSEGVAYAKDVEIGMMIEVPSAAVISDVLAKHVDFFSI
                     GTNDLIQYTCAVDRMNQKISYLYNQFNPAVLRLIKTVIDNAHKEGKWAGMCGESAGDQ
                     KMIPILLGMGLDEFSMSPISILPARKLITSVKESDMKKLADDVLNMGTAEEIKSYIEK
                     TFNI"
     gene            38381..39931
                     /locus_tag="KOU88_002589"
     CDS             38381..39931
                     /locus_tag="KOU88_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3212460.1"
                     /translation="MRYKKRNIDKSSELSFQSLAKYFITFYIVIILIILSMFCINTIW
                     VMKKDNQDLLSTTSNRIEDRVGETIKLLNSLSKDNYIIDNSVNGIDKSKELSMYSDEF
                     GYMMICFVDKNIIVWDEEGGNISLAGRDYMQKLFATKKYQVTDSFAAGADGKTLNYTI
                     ASPIIKNGNVDGCVFAAIYFDEIKDILKQGKGQQQQNFILFGSENQIMNLTSDETAYG
                     EKYMKLSQKTKYLGTNAKKVEKDMFNNKSGDYWAFENGKLYFMSYKPIKNTNWSLFCK
                     VNFLDIFALNLIPMGAILSVITLVFIILICMEKSFMKKRMEVIDMLLGSVQELEKRIY
                     QTERPSEVDFKEIIQLTSKGLTDGLTGVVTRTVFFDQIYNRVEMEENDKLSVISFVDL
                     DDLKCINDLYGHEIGDMVLKNVGYVLREYEIKYNGLIGRYGGDEFVMLLSGFTSREEV
                     EDLLDEIAIRLHTEVLTDDGIIQTHCSVGAVVCSVKDNKDIDNLLKQADEALYYVKRN
                     GKGNYHLV"
     gene            39957..42659
                     /locus_tag="KOU88_002590"
     CDS             39957..42659
                     /locus_tag="KOU88_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3212461.1"
                     /translation="MKNVSKKFFVCTIIVLITFLCFSKFAIYVFDKQEKKETKVVENM
                     LNVYKNNIILNLTEKFNYSKDLTSVLVSNNYSIDKLKPIADEILKNNSCIYISVVEKY
                     NVAAFFSNSVKKDIINTPIQELNYSYSLANSIKGLVVEGPSKDQFSNGDVFLITNPIY
                     KNGEYWGEITVALDAKKVVDSFNLNKLKESGFEYELWRVHLDNGSKSTIEISTKDFNF
                     SKSHEIKFKLPTVWTLSIVYKNGWNNKNIDFIVFVILLIISILIGVMTFIYIEKKSIG
                     KELNQQSLKNLETGILNREGFLIKLQEHLNRKNNEIVLLYICITNYSKFAPVMSFEKR
                     QDYLTHIVKNLDNYIKSSHFIARISEEGFVLALEENCDKNELLNIEKGISLELLRKIK
                     VENKQVFLTIGYGSSRCVDDRKDAESLLLSAIEDYERRFPAMSPIHDFTKKCEDMLDE
                     KKQIVFGEYPDLEINKLSKVIYKYYKKVQRIMYKDYNIDIGNRRGYMRDVQVLIDYNS
                     ERMLYLFLIDICKFGKFNELFSIEIGDVILKEVSNKLKTIFSNYLYRINGDVFLGISI
                     DKESYLDTLHKVNEVFNSSLSVEDVLFDVKCNIGICQYPYHGENPYDLLEKVQIALEY
                     AKKDVKSNVKVYDKELTEEIYHENNIIKDLKKGLEEQTLEVWYQPIFNVSKNCYIKAE
                     ALIRLRNKEGGYYSAYEVITYAEKHGLIKDVGLYVLKKACDVTTKIKDKNIDFEQMQL
                     NLSVQQIVHKQCANDILSCIENCGLDKKYICVEVTETVLMETFEIVNVTLDKLKKEGI
                     SIALDEFGSGFSSINYLANLPIENLKIDKELVEQITYSKKQFELLKTIVQIAKINGMD
                     IVAEGVETKETLDLVVTSGVNLIQGHYFSEPLSEDKFIELMIEE"
BASE COUNT        17171 a         4422 c         7581 g        13850 t
ORIGIN      
        1 aatttcaaat aatgctgtag attctaaact tatgaatagt aggattaaat caatagatat
       61 aataagaggg ctatcaatag ccctcatgat agtctgcaat aatcctggga cttggatgag
      121 aatgtatcct caattaagac atgctgtatg gcatggtgta acacttgcag attttgcatt
      181 tccttttttt gttatatctt taggtgttac aattccaata tcaataaata gtaagataaa
      241 aaataataaa tccacactga gtataatact tagtatatcc aagagaagta tcttattgat
      301 attatttgga tttttcttaa attatctagg aaatcctgat ttagatactg taagaatact
      361 tggagtactt caacgtatgg gattagtcta ttttgtgact agcttagtat atttactgct
      421 aaaaaaatta aatgttggaa gtactgctac aataattact ttcttatgta tatctacatt
      481 tataatagtt gggtactaca tattagcaaa accttatgga tttgagctag aaggttctct
      541 tgcacagtta gtggatttac atttcttcaa aggacatttg tacaagccgg aatttgaacc
      601 agatggtttt ttaactagta tagtagcaat ttcttcaggt atgttgggat gcactatggg
      661 atgtgtactt ttaaaagaag acataggaga atataaaaaa ttctttaaaa tactggttat
      721 gagcataatc ctgctaatag gtgcttttat ctttaatcag tattttccat ttaataaaag
      781 attatggtct agctcatttg tacttttaat ggctggcagt tatggtgtat tactgtcaat
      841 attttatttt atatgcgaca tcaaaaataa aagtaaaata tttaccccaa taatagcact
      901 tgggagtagc cctattttta catatatgtg ccttgagata ttgagtcatg ttttttggaa
      961 tgttccaaaa cttacgaaca aagtcgatta tccaactacc ttggtagagt ggactacata
     1021 tgaacttata acaccttggg caggtacaac ttgggattct cttgtatttt ctttattgta
     1081 tgtactattc tggattatag taatgtctat aatgtacaag aaaaaaatat ttattaaaat
     1141 ttagtgcaat atttttagac gctaaagtct ttgatttgtt caaatataca gaaactatca
     1201 aatataatca aaatttctcc tcgataaaat ttaaaaacca tgccataaaa gattacaaaa
     1261 agtttacaat ttgtaatttt ttgtgctata atgaaaaaag atttacataa tattgaattt
     1321 atgtaatata aaacaagctt aagatgtatt aaaaaagatt taaagagtta aagaaccaaa
     1381 aaattagggg ggatatgatg aaaaaaacaa caaaattatt ggcaacagga atgctgtctg
     1441 tggcaatggt ggcaccaaac gtagctttag cggctgaaaa tactactgca aatacagaat
     1501 ctaattcaga tattaatata aatttacaaa gaaaaagtgt agtgttagga agtaaatcta
     1561 atgcaagtgt aaaatttaaa gaaaaattaa atgctgattc aatcacatta aattttatgt
     1621 gttatgatat gccacttgaa gctactttaa attacaatga aaagacagat tcatatgaag
     1681 gtgtaataaa ctataacaaa gacccagaat acttaaatgt atgggaactt caaagcataa
     1741 aaataaatgg taaggatgaa cagaaagttt taaacaaaga agacttagag tctatgggat
     1801 taaatcttaa ggattatgat gttacacaag agtttataat aagtgatgca aattcaacaa
     1861 aagcagtaaa tgaatatatg agaaaaactt ctgcaccagt aaaaaaactt gctggagcta
     1921 ctagatttga aactgctgtt gagataagta aacaaggttg gaaagatggg tctagtaagg
     1981 ttgtaatagt taatggagaa ttagcagcag atggaattac agctactcca cttgcatcta
     2041 catatgacgc accaatatta cttgcaaata aagatgatat accagaaagt acaaaagcag
     2101 agttaaaacg tctaaatcca agtgatgtaa taattatagg tgatgatggt tcagtttcac
     2161 aaaaggcagt gtctcaaatt aaatctgctg taaatgtaaa tgtgactcgt attggtggag
     2221 ttgatagaca tgaaacatct ttacttatag caaaagaaat agataagtat catgatgtta
     2281 ataaaatata catagcaaat ggatatgctg gtgaatatga tgctcttaat atttcatcaa
     2341 aagctggtga agaccaacaa cctataatat tagctaataa agattctgta ccacaaggta
     2401 catataattg gttatcttca caaggtttag aagaagctta ttacataggt ggtagtcaaa
     2461 gtttatcatc aaaacttata gaccaaatat ctaaaatagc aaaaaatggt acttcaaaaa
     2521 atagagtttc tggagcagat agacatgaaa caaatgcaaa tgtaattaag aatttctatc
     2581 cagataaaga gttgagtgca atgttagttg caaaatctga cataatagtt gattcaataa
     2641 cagcaggacc tttagcagct aaattaaaag ctccaatact tataactcca aagacttatg
     2701 tttctgcata ccacaataca aatttatcag aaaaaacagc agaaacagta tatcaaattg
     2761 gtgatggaat gaaagatagt gttataaatt ctatagcatc tagtttatca aaacacaatg
     2821 caccaacaga accagataat tcaggttcag cagcaggaaa aactgtagtg atagacccag
     2881 gtcatggggg ttctgattca ggggcaacaa gtggattaaa tggtggagca caagaaaaga
     2941 aatatactct taatacagca ttagcaacta ctgaatattt acgttcaaaa ggtataaatg
     3001 ttgttatgac tagagataca gataaaacaa tggctttagg agaaagaaca gcattatcaa
     3061 atactataaa gccagattta tttacaagta tacattacaa tgcgtctaat ggatctggta
     3121 atggtgtgga aatttattac aaagtaaaag ataaaaatgg tggaacaact aagactgcag
     3181 catcaaatat cttaaaaaga atactagaaa aatttaacat gaaaaataga ggaatcaaga
     3241 caagaacact tgataatgga aaagattacc tatatgtgtt aagaaataac aattatccag
     3301 caatacttgt tgaatgtgca tttattgaca ataagagcga tatggataag ttaaatactg
     3361 cagaaaaagt aaaaacaatg ggaactcaaa ttggaatagg aatagaagat acagtaaaat
     3421 aaaataaaaa atattaaagc aaaacatatc atctcctgtt ataatgtaaa atataacaag
     3481 agatgatata tttttgtaaa gaatcaaatt gtttacaatg atgtttcttg tattgataat
     3541 ctgctcatta ttgagtataa tatagaaata agtcaaaaat aagatagaaa taagttgaaa
     3601 ttaagaatta aaaaaatttt tattccaata tggaggtaac tatgtctgga tatactaatg
     3661 atgagtgtga aatacctaaa attaaaagct atccaggggc agataaagaa attgcaagtg
     3721 agattgacta tagcatagta aaaggaacag ttttattcga cttgtaccaa agaattatgg
     3781 atttagtttt atctataata ggacttgtga taggtttacc tttaatagca atatttggaa
     3841 ttcttattaa aatagaggac aaaggaccaa taacttataa gcaagaaaga ctaggaaaat
     3901 gcgggagaag attctatata tataaattga gatctatgag aacagacgca gaaaaatttg
     3961 gcgcacaatg ggctgaaaaa gatgatccta gaataactaa ggttggaaag tttattagga
     4021 aaactagaat tgatgagatt ccacagctgt ttaatatatt aaagggggac atgggcttaa
     4081 taggtcctag accagagaga ccgaacttta ctgttcaatt taatgaggaa atacctggat
     4141 ttatcaacag gctcgctata aaacctgggc ttacaggttg ggcacaagta aatggtggat
     4201 acgaaatcac tcctgaagaa aaacttaaag aagatattta ctatataaaa aataggagta
     4261 tattacttga ctttaagata ctctttaaaa ctgttaaagt agtattgaca ggagacggag
     4321 ctagataatt ttaaaatatt agattactaa tcaatgaaaa agctctttaa aaagagcttt
     4381 tttattgtca aaaaatacaa aaaagaaaag gaatgagaac ttatgattaa aaaaatttct
     4441 actatattat cgttagtttt gttaatctct atttctagta cgataggagt atttgcagat
     4501 gcaaatccca aaagagagtt gatagaaggg agtataccag aaatttcgac agaattaaat
     4561 aaaagagcat ttaaggattc taaagaagta attcttgtaa atgaagagtc aattgtagat
     4621 agtataagtg caacaccttt agcatatgca aaaaatgctc caatagttgt aactaagagt
     4681 aaaaatcttg gtagagtaac aagaaattat ctaaaagaac taggtccaga gaaggttacg
     4741 atagtaggtg gtttaaaggc aatatctaaa gatgctgaac gtaatataga aaaaatggga
     4801 atgaaagtag aaagaataag agggaaagac agatatgata catctttaaa gatagctaga
     4861 gaaatgtata gaacagtagg atttgatgaa gcatttttac ttagctcaac aacaggatta
     4921 gagaacgcca tatctgtata ttcttatgcc gctaaaagtg gaatgccaat aatatgggct
     4981 aaagatgaag ggtttgagga acaaattgat ttcttaaaag gcaaaaatct taaaaaaata
     5041 tatgcattag gtgattcaaa agaatttatt gcagagattg attctaattt aaaaaatata
     5101 gaaggaataa agcaaataaa taagtcaagt acaaatgttg atttaataaa gaagttttat
     5161 gatgaaaaag atataaagaa aatctatact gctagattag actttggtag cagatctgat
     5221 gtaaacgaat atatttcttt gggagtagta tcagcaaaag aaaatatgcc aatactgatt
     5281 tgtagtgata acttaagtcg tgcacaagat aaattcttga aagatagcaa tataaatgat
     5341 gtagttgaag ttgggtatac agtaggtgat tatagtctat ttaggagcat atttaatcta
     5401 acattcttat cttgtatagt attaatacta ttattactat tgattacatt tagggcactt
     5461 agatatgagt cgaaatagtt tttgatttat aaggaagctt ttcataggtt aaatttactt
     5521 aattagaata atgtttataa gcagttttaa aagttctact tttagagttt aaattagata
     5581 aggagaaaga agatgtcaaa aacagctaaa gcagcattgt ggattatggc agccactatg
     5641 ttttcaaaag tattaggttt ccttagagaa cttgtacttg caaatttcta tgggacaggt
     5701 atgtatgcag acgtatttgt attaacatta aatatacctg gtttaatcat agcagtcata
     5761 ggctctgcag ttgctacaac ttatatacct atgtactttg agacaaagaa aagactcgga
     5821 gatgaaggtg ccttaaaatt tactaataat gttttaaata tatgctatat aatggctata
     5881 gtaatagcta ttattgggct tttatttaca gagcaatttg ttacagtatt tgcagcagga
     5941 tttagaaacg accctgctaa gttccaagca gcaatattat ttactaaaat aatgatttca
     6001 ggagttttat tcctgagtgg aagtaaaata tttagttcgt ttttacaggt gaatgacagt
     6061 tttgtaattc ctgggcttat aggaatccca tataatatta taataatagc agcaatagca
     6121 ctaagtgcag gtaaaaacgt atggatacta ccagcaggag cactattggc tatggcgagt
     6181 cagctattgt ttcaactgcc atttgcattt aagaagtcct acaagtataa gccatatata
     6241 aatttaaagg atgagtctat aaaagaatta gtcaacctag tattacctat gttggtagga
     6301 gtagctgttg gacagttaaa tatatttgtt gacagattat tggcaaccac tttgggtaat
     6361 ggaaagttgt ctgctcttaa ctatgcaaat aggctaaatg agtttgttat ggcattattt
     6421 gttacatcta taataacagt tatatatcct aaactagcaa aaatgtctgg taaagataat
     6481 aaagaaggat ttataagtac tattgtaaaa tcttcaaatt gtattatatt ggtggtgctt
     6541 cctatatcta taggagctat tatattagca gagcctcttg ttaggatatt attccaaaga
     6601 ggtaaatttg atgcgttatc aacagacctt acatctatag cgcttagatt atattcacta
     6661 ggtttattgg cttgtggagt aagagatgtc ttatataggg cattttactc tctttcagat
     6721 acaaaaacgc caatgataaa tggaagtata gctttaataa taaatatagt tcttaattta
     6781 atattgataa gaccattggg tcatgcaggt attgctatat caactagtac atccaacata
     6841 attacagtta tattattatt tatatctctt aaaaagaaaa atggatattt tggaggggat
     6901 aaaattataa agactggtct aaaaagtttg gtagcatctg gtgtgatggc agtagctact
     6961 ttattgatat ataataatct atatgcattt atgggttcag gaacaattaa agaaattata
     7021 tcagttggag ctggagtatt aggtggagct tctgtatata ctgtattgat agttttattt
     7081 aaggtagaag agatggattt agcttttgaa tttttaagaa aaggaaaaca aaaactactt
     7141 agaagataga taattacctt gaaattttaa attagagtca gaaaggatga aaatatggat
     7201 tataagaata attatgagat gtggttaaat tctccttatt ttgatgaaca aacgaaaaat
     7261 gagctattaa gtataaaaga tgatgaaaaa gaaatacaag atagattcta taaaaattta
     7321 gagtttggaa caggtggttt aagaggtata ataggagcgg gaactaatag aatcaatatt
     7381 tatactgtta gacgtgcgac actgggcgtt ttaaattata tcatgaaaac tcaaggagaa
     7441 gaaggtaaac aaaagggaat agttatagca catgatagta gatacatgtc tagggagttt
     7501 tgtatagaag tagcaaagac tttaagtgct tatggtgtaa aggcttatat ttttgaagaa
     7561 ttaaagccta caccagaact ttcttttgct gttagatatt taaagtgtgc tatgggaata
     7621 gtaataacag caagtcataa tcctaaagaa tacaatggat ataaagtata tgactcagat
     7681 ggtggtcaaa tctgtataga tatggcaaat gatataatag cagaagttaa taagattgat
     7741 gattacagta ttattaaaag tatagatttt gaagaagctt tatctaaaaa tttaataact
     7801 atattagata atgaagtaga tgatgagttt ataaaagctg ttaagaagca agttttaaga
     7861 caaaatataa tagatgaatg tgggaaaaaa ttaaaaataa tatatacacc tattcatggt
     7921 acaggaaata agccagtaag aaaagtctta aatgaatgtg gttttgaaaa tgtaatggta
     7981 gttaaggagc aagaattgcc agattctaat ttttcaacag taaagtatcc taatcctgaa
     8041 gaaaagtcag tgtttaatat agctattgaa atggcaaaga ataatggcac tgatttgata
     8101 ataggaacag accctgattg tgatagagta ggtatcgttg taaaagattc aagtggtgaa
     8161 tatgtagtct taaatggaaa tcaagtcggt tcacttttag ttagatatat attagagagt
     8221 ttagttgaag aaaataaact tcctaaaaac aatcctacaa taataaaaac tatagttaca
     8281 tcagaactag gtgcaaaaat agcaaaggct tataatgtag attgtttaaa tactttaaca
     8341 ggatttaaat ttataggaga aaaaataaaa gcgtttgaag aaagtaatga tagaagtttt
     8401 ataatgggat atgaggaaag ctatggttac ttaattggaa ctcatgctag agataaagat
     8461 ggtgttgtat cttcacttat gatatgtgaa atggcagcat actattcttc aaaaggtatg
     8521 aacttgtatg aagctttgat agatacatat aataaatttg gatactacaa agaggactta
     8581 aagtcagtaa ctttaaaagg catagatgga ataaaaaaaa taaaagagat gatgctttac
     8641 tttagaagtg ttaaaataga taatgtggct gatgtaaaag tagataaaat tttagactat
     8701 aaagatggtg ttgatgattt acctaagtca gatgtactta aatttttact tgaagatggc
     8761 tcttggatag ctataagacc ttcaggtaca gaacctaaaa ttaaatttta ctttggagca
     8821 aattcagaca atcaagaaga tgtagaattt aagttgaaca atttaatatc ttatatatta
     8881 aatgtagtgg attctatata aaaagctaag gggagataaa taatgaaagt atacaatgtc
     8941 ataatggctg gaggaggagg aactcgtttc tggccactta gtagacaaga agtacctaaa
     9001 cagcttataa atttaagtgg agaagatgct ttaataaatg aaactataaa cagaatagat
     9061 tctctagcaa aaaaagatga tttatttata gtaaccaatg agaagcaatt ggaagcttta
     9121 aaggatatag taaaagataa atgtttggat agtaatatat tgccagagcc atgtgccaga
     9181 aatacagcag cagctatagg ctttgcagca tttaacataa tgaaaaaata tggtgatggt
     9241 gttatgtgtg tatatccagc tgaccattat ataaaagatg aaaaagaatt taaatctatt
     9301 ttggaaaaag ctatctatat agcagaaaat aatgataaac tagtaactat tgggataact
     9361 cctacatttc catcaacagg atatggatac ataaatttta atagagaaaa tactatagaa
     9421 gatgttgcat atgaggtagt ggagtttgta gaaaaaccaa actatgaaat tgctaaagaa
     9481 tatgtaaact ctaaaaagta tgtatggaat agtggaatgt tcgtatggaa ggtatctaaa
     9541 atactagaag attttaagag atacttgcca aaagtatatg aaaaattaga agatataagt
     9601 aaatacttag gaacaaaaga agaaatggaa aaaataaaag aaatataccc aactatacaa
     9661 tcaatctcta tagattatgg tattatggaa agaagtaatg atgttatagt agttcctggt
     9721 gattttggat ggaatgatgt tggttcttgg gattctctag gtgcaatata tccaactgat
     9781 gatgaaggta atatcaaaag aggtgaaaat attactatag atactaaaaa ttcaattata
     9841 tattcagatg acaaattaat atcgacaata ggtattagtg atttgatagt agtatctaca
     9901 aatgatgcag ttatggtttg tagaaaagat aaagctcaag atgtcaaaaa aatagtagag
     9961 cagttaaaag aagaagatag acaagaatat atgtaggagg tgttcatttg attcctaaaa
    10021 aaatacatta tgtatggttt ggtggtccaa aaggaaatat agaaaatata tgtataaatt
    10081 cttggaaaga aaagcttcca gaatatgaga tagtagagtg gaatgaaaaa aactttgata
    10141 tagagaaaga aataaaagga aataagtttt tggaagaatg ttataaaaga aaactttggg
    10201 cattcatatc tgattataca agaataaaag tactctatga acaaggtgga gtttatatgg
    10261 atacagatat gcaaatatta aaggatataa ctcctctttt agaaaataat aggctaatct
    10321 gtgggtatga agatgataga gagtatataa atggtgctat aataggtgta gaaaaaggac
    10381 atcctttttt aaaagactta ttggagtact atgaaaaaga agtacttact tcttcattgt
    10441 ttacaatacc aaagataatg actcatctta tggaaaagaa ttataagaag attgacccaa
    10501 ataattatga agaaggaata cgtgtttacg acaaagaata tttttatcct tttggattta
    10561 aagaagactt tacaccagaa tgtataacag aaaacacttt tgggatacat tggtggggaa
    10621 aaagttgggc taaaaagaga aattatttct tagaaagcaa acacttaaca ggtgtaaata
    10681 agatatggaa gtgttgtaaa atatttgcaa gtaatacttt acgaagctaa aagggagaaa
    10741 gtaaaatgaa gactttaaat gatgatagaa atattatgat tagaaaatat ctttatatat
    10801 ttgttttgtt tatcatatta cttagaaagt atatgatatc atttattgac ccaaatatgg
    10861 atatagggat gattaaatca gcgttatttt attcttcaat aggaatacta atgctacttt
    10921 ttttatttga taagagaaaa agtataacag aaatggtact agttggagtt tgtgtcttac
    10981 tttatttatt aaatagggaa ggagctatat tattaatcgt tttattagct gtatcagcta
    11041 agcaaataga tgataaattt atagttaaaa attatttaat aatatcagca tgttttttaa
    11101 tggtagctat attattattt aatctatttc cttcattaat atttaatcag gaagtccact
    11161 atagatatat agaaaaaata gatatgcttg ttacaagaat ggattttgga cttggtaatc
    11221 caaatagtgt attttatcat atggttacta tatatgcagc atatatattc ttaagatata
    11281 aagattataa taaatgggat agaataattt tatttggttc tgcatttttt gtttatcaaa
    11341 ccacatatag tagaactgga tttttcacta tattagcagg attaatattt gtagaaataa
    11401 taagatggat agatataaaa aaaataaaag gactaccaat gctcctaaag acattaccaa
    11461 taatacttac tttatttagt gtaattattg gtacagtatt tgataaaagc actttattaa
    11521 atagattatt agcaagtaga cctaagttct ggcatgtata cttggctgaa aaggggaatt
    11581 ttctaaaacc ttttggaaat tcatatagtc ctgctataaa agcaactaat ccattagata
    11641 gttcttatgt atatataatt agtgtactag gagtagttgc ttgtatatta tttatgtatt
    11701 tgatgtataa aggaatagaa agctttatag aaaaagataa aaaagcatat ttagtagctt
    11761 tatttatatt tttactatac tcttttgcag aaaatttatt attagaagct tcatttagtt
    11821 ttgcagtagt attactaata aaagaagtga tattaaatga taaaagggaa atagatttgt
    11881 ggaagatgaa aagtaggagg tagtaatgtt aatatcatta ataatgccaa cattaaatag
    11941 atatgatgat atatacttac ttatggacag cttagaaaat caaacttaca aaaactttga
    12001 acttatagta gtagaccaaa atgataatag caaagttaaa gaaatagttg ataaatacat
    12061 tgataagtta gatataaagt atataaaaag ctctaaaaaa ggattgagtt ataacagaaa
    12121 tgtaggcata gacaatgctg tagggcaaat tataggtttc cctgatgatg attgtgtcta
    12181 cgaaaatgat acattagaaa aagttataaa tttctttaat aaaaataaag attataaaat
    12241 atacagttgc aaaactatgg attcaaataa agttgatgca tttaagaaaa tgtatgatgg
    12301 aacttgtgat atcacaagtt ccaacgtttt ggatactata acatccataa ctttttttat
    12361 tgattttgaa ggtaaagact atacaagatt tgatgagaaa ttgggtgttg gtggagagtt
    12421 tggtgctggt gaagagatag attatgtttt aaacttattg agtttaggtt ttaaaggaaa
    12481 atactttgga aatgatataa tttaccatcc tgcaaaaaaa cattctaaat ctaaagaaaa
    12541 gtatcaaaaa gattataact atggaagagg ctttggagcg ctttgcaaaa aggaaatagt
    12601 ctatagaaaa aattataagt ttgcaaaagt tatggtatca aaacttgtaa gaaatatagg
    12661 aggtcttata ttgagttcca atagagatta tcatagtgcc actataaaag gaagaattaa
    12721 tggatttaga cagtacaagt tataatgagg atggtgttta tggacaaggt taaattttta
    12781 ataaatatgc ttttggcttt ttttatatat ccatttaata agcataagtt taatggtaga
    12841 gatatctggc ttataggtgg acattcaggg gatatataca atgataattc aaagtttttt
    12901 tatgagtata tgctaaaaga acataatgat gtagaaactt attgggtagt aaataaagac
    12961 agtaaagtat ttgataaaat tccaggcaaa aaattaataa gaggaagtgt agaaaactat
    13021 ctgtattatt acaattcaaa agctatagta ttttcacatg caccatcagc agatatagca
    13081 ccatacaatt ttgctgtacc tgttcttaat tattttcata aaaaaacgat aaaagtgttt
    13141 ttaaatcatg ggactataag ttttaaaaaa agaaaaccta tgaacaaaaa gttcaaaaat
    13201 attatagata acctatataa aagctataat atagttacag caagttctga atttgaaaga
    13261 aatgttatgg taaatgattg gggaatgtta gatgactcag tttatataat tggaaatgca
    13321 agatatgaca atttaccaac aaatgaagtt gcacaaactc gagatatatt atatactcct
    13381 acatggagag attggataaa atttagttca ggaaaattta cggatacaga ttattttaaa
    13441 aatataatga attttttaaa tgatgacaaa ttaaataaaa tattagatga gaaagatata
    13501 aatgtaaaaa tttatatgca tcatcttatg catgagttta tagatgatat aaaagaaaat
    13561 ataacaggaa aacgaattgt gtttttagat aaaggggtaa ctctagcaaa tgaaatcaga
    13621 aaatcagctg caaatataac tgattattca agtgtagcca tagacttttt gtatatgaat
    13681 agacctatct tgttttacca attcgatttg gatgaatata tggaaaaagt tgattcatat
    13741 atagatttaa aaagtgaaat gtttgggtct ttggcttata ataatgatga agctgtgaat
    13801 aaacttattg atattattga aaataatttt gaggttatgg ataaccaaaa aaatgaaaga
    13861 aataagtttt tcagatataa tgataataag aactgcaaga ggatatatga ttgtgtatta
    13921 agtaaaatta aataaatatt ttataaatga tgaggaaggt aatatgaaga agaatttagt
    13981 atctataatt actcccatgt ataattctga aaaatttatt gaagcaacca taaaatcagt
    14041 attaaaccaa acttatcaag aatgggaaat gttaattatt gatgattgct caacagataa
    14101 tagtcctaat atagtcaaat cttatatgca acaggatagt agaataaaat gtataaagac
    14161 tgagactaat aagggtgtct ctaatgctag aaatttagca ctaagtaagg caacaggaca
    14221 atttatagct tttttagata gtgatgacca atggaatagt agtaagttag aaaaacaagt
    14281 aaattttatg ttagaaaatg actatgtaat ttcatttact tcatatgaac tgatggatga
    14341 aaatgataaa aaattaaaca aagtaataaa agttccacct aatgtagatt atagaagatt
    14401 attaaaagga aatatcttag gatgtcttac tgttgtgatt gataagtcta aattggattt
    14461 tgaaataaga atgagtggtg taagacatga agattatgtt ttatggttat cgatattgaa
    14521 aaaagggcat attgctcatg gaataaatga agttctagca ttatatagaa aatctagcaa
    14581 ttccctaagt ggtaataaaa taaaagctgc tatgtggact tggaatatat atagaaatat
    14641 agaaaaaata cctttataca aagctatata ctactttatt aattatggaa taaacggaat
    14701 caaaaaaagt tagacagaga ggaagattta attaatgtat aaatataaat ttactgtatt
    14761 tactccgacg tataacagag ctcatttact tgaaaatttg tacaatgatt taaaagctca
    14821 aacttatgat ttcaatgatt ttgaatggtt gattgttgat gatggaagta gcgacagtac
    14881 taaagagtta gttgaaaaat ttatatcaga aaataaatta aatataagat atatatacaa
    14941 agaaaatgga ggaaaacata ctgcaataaa tctaggtgta aaaaatgcag atggagagct
    15001 atttttcatt gtagatagtg atgatggttt aattaaagat tctcttgaaa ttgctaatga
    15061 tgagtgggat tctttagaga ataaagaagg atttagtgga gttgttggac tttgtgtata
    15121 tccaagtgga gatttgatag ggacagaaat gcctgaagat aagaaaatat gtcactttgc
    15181 agacctatat tttaagtatg gcgttaaggg agataaaagc atagtatttg taactgatga
    15241 gcttataaaa tttccttttc cagaaagaaa agaagtgaga tttttaccag aaagtgtagt
    15301 atggaatgaa atgtctaaat actataaagt tatatgtgta aataaaccta tgataataag
    15361 agattatttg gatgatggtt tgactaagaa tatattaagt aaaaatgcat taagaggtag
    15421 agcattagag tttttatatt taataaatca aaatacatat ccattaagta gatatccata
    15481 tatgtggata aaaaattaca taaatttagc cagatactca ttgttgtctg atagtcatta
    15541 ttttggtgaa ttaagaaaag tatctgataa attgttgtat ttagcattat tcccattagg
    15601 atattacaaa tatattggac aaagaaaatt agtatctaag taaacttgtt ggtatagtac
    15661 tgctagttgc tatataagga gagtaaaaat atgaatgagc ctttagtatc gataattact
    15721 cctgtttata attcagaaga gtttttatca gagacgataa agtcaatcca aaatcaaact
    15781 tataaaaatt ggcagctttt attagtggat gattgttcta aggacaattc aagtgaaatt
    15841 ataaaaagtt ttcgaaaaga agatgctaga ataaaatata taaagcttga aaaaaattct
    15901 ggagctgcag tatctagaaa tgttggtatt aagaatgcgg aaggtcgatt tattgcattt
    15961 gtagatagtg atgatttatg ggatagtaga aaattagaga ttcagataga atatatgtta
    16021 aaagaaaatg taggtttttc ttttacatct tatagatata tgagacaaga tgggtcaaaa
    16081 acgaataagg ttgcaagagc tcctaagaaa attgactatg aaggattact tagaaatact
    16141 ataataggat gttctacagt ggtcattgat aaggagattg taggagagtt cagcatgcct
    16201 ttggtaagaa gaggacaaga tactgcaacc tggttacagt tacttaaaaa ggaaaaatat
    16261 gcatatggga ttcaagaaga tttagtgaat tacagattag ttggaaattc tatatcaagt
    16321 aacaagataa aagcattaaa acgaacttgg aatacttata gaaatgttga aaatttaagt
    16381 ttaccaaaaa gtctatatgt attttgtttc tatgttttta atgccattaa aaaaagagta
    16441 taagttttat atacttggag gtaaaaaaat gaaaatagct atagctggga cgggatatgt
    16501 aggtttggtt acaggtgttt gtctagcaga ggtaggcaat gaaaatgtag tctgtgttga
    16561 tgtagatgaa caaaaagtta aatcaatgaa acttggaata gcacctatat atgaagaagg
    16621 cctagaagaa cttatggtta aaaattacaa cagaggaaga atagattaca ctacagacta
    16681 taaaaaagct tatgaagatg tagatgtaat attaatagct gtaggtacac ctgagagaag
    16741 tgatggctca gccaacctag attatataaa ggcagttgca aagcaaatag ctgaaactgt
    16801 gacaaaagat actctagtag taataaaatc tacagttcca attggtacaa atgaagagat
    16861 agaagattat ataaatagaa acctaaaaaa tgatgtaaaa gtagagcttg catctaatcc
    16921 agagttttta tcacaaggaa cagcagtaaa agatactcta catgcttcaa gaatcgttat
    16981 aggtgtagaa agtgaatggg ctagagaaat attagaggaa atctataagc cttttaatca
    17041 acctataata gttacaaata gaaatagtgc tgagatgata aaatacgcat caaataactt
    17101 cttagctctt aaaatatcat ttatgaatga tattgcaaat ctttgtgaaa tagcaggagc
    17161 taacatagaa gatgtagctt taggaatgag ttatgatgat agaataggaa gtaagttttt
    17221 aaaggcggga ataggatatg gtggttcttg ctttccaaaa gacacaaaag ctcttcactg
    17281 gttatctgaa cataatggtt atgaattaaa aacagtaaaa gctgcaatag aagttaatga
    17341 aagtcaaaaa cttaaattag ttagaaaggc atctaagtta gtagagagct ttcaagatat
    17401 gaaggttgct gttttaggtt tgacttttaa gccagacact gatgatataa gagaagcacc
    17461 atctatacca aatataaaat atttgctcga aagaggggca agagttactg tatacgaccc
    17521 aattggtgta aataatacta agaaaatatt tggtgactct atactttatg ctgattctgt
    17581 agatgatgcg atagaagatg cagagatatg ttttataatg acagaatgga aagatgtatt
    17641 aaattatgat atacataagt ataaggaaaa gatgaaaaat cctttagtcc ttgatggaag
    17701 aaattgttat aaaattaaag atatggaaga gttaggaatt gagtattatt cgataggaag
    17761 gtaaatatta tgaagactgt ttgttattta gctgatgggt caaatcctca tactttaaaa
    17821 tggtgtagtt tttttaaaaa taaaggatat gacattcatg taatctcttt aaatggaggt
    17881 cacatggaag gaataaaaat ttataatttt ggttctaatg tagaagaact aaaaaatgaa
    17941 aatatttcta aaaaaacggg atacttaggt tcaataaagc agataaagaa gctagtaaat
    18001 gaaataaagc cagatatatt gcatgcacag tatgcaagta gttatggatt tataggaagt
    18061 ctacttgggt atcatccata tattatttct gtttggggta ctgatattta tgatttccct
    18121 aataatggtt ttatacaaaa acaaattata aagcataact ttagaaaagc agactatatc
    18181 ttttcaaata gtagagatat ggctaaagag gctaataaat atacagctaa acatgtagat
    18241 gtaacctttt ttggagtaga tatggatagg tttaagccta tggaagtaga aaaagaagac
    18301 gcttttgtaa taggaattat aaagagttta gaaaaaaaat atggaataga atatttaata
    18361 caagcattta agatgcttaa agatgaatat aaagataaga aaataattct taaaataggt
    18421 ggctctggaa gtcagatgga caacctaata aatttagcta aagaattggg tatagaaaat
    18481 gatgttcagt ttttaggaag aatatctcca gaaaatgtaa gcaagacttt taattctttt
    18541 gatgtaactg tatttccttc tttaagagag ggatttggag tggcagctat agaatcagaa
    18601 gcatgtgaag tacctgttat agttacaaat gtaggaggac atccagaatc tgtatgggaa
    18661 aatgaaactg gcttaattgt agaaccaaaa caaccagaag aaataaaaaa tgctataata
    18721 aaactaatgg aaaatgatga acttagactt aatatgggta agaaagggcg tcaatttgtt
    18781 agagaaaatt atgaggttaa tttaaacttt aatgatatag aaaaaattta tgattctata
    18841 tttgataaat ataaaaaata aaatgaaaaa atacagcaaa agatagatgt tgttggctat
    18901 gcttaggtgc gtagcttttg ctgtttaaag gagggcttct agttatgcga gaaagtatag
    18961 atttagagaa agaaagcttt tttaataggc tttttaaaaa atataaattt agacatttaa
    19021 cactattaat tctagatatt tgtagcgtac tagtagcgtt tcgaatgtct ttaagcttga
    19081 caggtaattt aaatgcattt accactaatg atataataat ttcagcgtgt atatatatag
    19141 tacttcatat agtatcattt agattgttta agtgctacaa cacattatgg agatatgcag
    19201 gagaagaaga aattatatct atttttatgg caactttagc ttatttaatt cctatttata
    19261 taataaataa attattaggg tttgattatc ctataatgtt ttatgtatta aatacaatat
    19321 ttattataat gtttacaagt ggtgcaagaa tagcctatag agctataaga atagtcatga
    19381 acaagacata ttctagagga aaggtttcaa atatccttat aattggtgca ggagatgcag
    19441 gagaaatggt tatacaggaa ctaaaaagaa atccagaact taagaaagta gcagtggcta
    19501 taattgatga tgataaaaat aaaattggaa gaataatcca taatgtgaaa attgtaggaa
    19561 caacttcaga tataaaagat gtggtagaaa agtacaatgt agatgagata atcttttcaa
    19621 tagcaaacat agagaaacgt agaaaaaaag agattattga tatatgtaaa aacactaact
    19681 gtaaaataaa gacaatacca ggaatttacg aaattataga tggaaaagtt gatataaaac
    19741 agattagaga agtagagata gaagacttgt tgggtagaga gcctataaaa acaaatttaa
    19801 gagagataag taattacatt gagggaaaag taatcctaat aactggagga ggaggctcaa
    19861 ttggttcaga gctttgtaga cagattgcag gatttaatcc taaagagctt attatagttg
    19921 ataattatga aaataatgct tactcaatac aacaagaatt acttagaaaa tataaaaata
    19981 aattagattt aaagacagta atagcatcaa taagagaaga aaaaagaatg gatgaaatat
    20041 ttaataaata taaaccagaa gtggtatttc atgcagcagc acataaacat gttcctctta
    20101 tggaatcgag ccctggcgaa gctataaaga ataatatatt tggaacttta aacatagctg
    20161 gcttgtcttc aaaatataga gctaagaaat ttgtccttat atctacagat aaggctgtaa
    20221 accctactaa cataatggga gctactaaaa gagctgctga aatgattata cagactatga
    20281 atgctgaaag ccagactgaa tttgttgctg ttagatttgg aaatgtgctt ggtagtaatg
    20341 gtagtgtaat tccacttttt aagaagcaaa ttgaagatgg cggaccagtg acagttactc
    20401 atccagatat tattagatat tttatgacaa taccagaagc agtaggctta gtcatacaag
    20461 ctggggctat ggctaaaggt ggagaaatat ttgtacttga tatgggagaa cctgtaagaa
    20521 tattggattt agcaaaaaac ttaattaaat tcagtggatt tgagccagat gttgatataa
    20581 aaattgaatt ttctggtctt agaccaggag aaaagttata tgaagaacta cttatgtcag
    20641 aagaaggtct gttggataca gagcataaaa agatttttat tggtagacca atagatgttg
    20701 atagagaaaa aataacaaaa tacttaaaac ttttaagaga aattactaac aatgaagagg
    20761 ttgaaaaaat agatggtatt atgagggaat tagtgccaac ttatattaaa ccagaagatg
    20821 ctaatatcaa agaaattgca acaactagag aaaagtagaa tatatttcta atttgtaacc
    20881 agggggagca aaaagaaaca aatatatact aaaaagaaac aaaagattac aaaaagatta
    20941 caaaaagatt acaaaaaagg ttgcaattta ttttgatgta agatagaatg ttaattagga
    21001 attggaaacg aaggaacaaa atgttaaatt ttcgaaagga ttaggtattt gagattatga
    21061 tgaatattaa aaataaaaaa catatattga aaaaatttat agctatggtg ttaatagcag
    21121 gagttgtcac agtagaagca ggagcaataa cggctagtgc agcagagcca actaattcac
    21181 ctatgagtgc aacagtagac cagtgtgatt ttttaaatgt aagaagtgga gctagtgcaa
    21241 atgatgcagt agtaggaaag ataaacacag gagacaaagt tgaagtttta gaattacatt
    21301 caaatggatg gattaaaata aaaagtgttg acaatgttac aggatgggta aatggagatt
    21361 atttaactat tcaaggtgga aatgtagatg caaaggtaca aaatgtttta aacttagcat
    21421 ttaagcaaca aggtaagcca tataaatggg gagcaactgg accaaattct tttgattgtt
    21481 ctgggttcac ttcatatgtc tataaaaatg gagcaggagt taatttacca agagtatcaa
    21541 gatcacaagc aacagtagga aagaaagtat caagagcaga attaaaacca ggagatttag
    21601 ttttctttgg ttcaggtggt tcaataaatc acgttggatt gtatgtagga gattctaaat
    21661 tcatacattc accacaaaca ggagatgtag taaaagttac tagcatggct ccaggaacta
    21721 attatgcaaa aagacttata actgctacac gtgttttaca ataataatag atattgattt
    21781 acataggatt gaatattaac attaaatata taattacatt taatgtttta catagagatt
    21841 taagagttta gtaatattaa aatagtgatg aacgttataa aaacagcaaa gaagataaat
    21901 ttctttgctg tttttttata ataaattatt tcatattata atcaaatatc aaatataaat
    21961 tttaactata ttattcaata tttgacagat aatatgaatt ttagatatac ttaataagaa
    22021 gtatattgta gaaaaaataa atttaaaaaa ttaaggggga tgaaatgaaa aaaataagta
    22081 tattagtatt atcattgata atgacactta ctatgtgtag tgtaagttca tttgctgatt
    22141 catcaaatga taaggaaatg agagctgctt ggatatctac agtttataat ttagactggc
    22201 ctaagactaa gaataatgaa gccaagcaaa aaaaggaata cacagattta ttggacaaat
    22261 taaaaagtgt aggaataaat acagcagtgg ttcaagtaag accaaaatca gatgctttat
    22321 ataaatcaaa tataaaccca tggtctgaat atcttaccgg tacacaaggt aaagaccctg
    22381 gatatgaccc attaccattt ttaatagaag aagcacataa aagaggaatg gaatttcatg
    22441 catggtttaa tccatataga ataactatgg cagatgagag catagataaa ttgccagcaa
    22501 accatccagc aaagaaaaat ccaagctggg tagttaaaca tggaaataag tattactacg
    22561 acccaggttt accagaagtt agaaagtaca tagtggatag tatagcagaa gtagttcaaa
    22621 attacgatat agatggagtt cattttgatg attacttcta tccaggagta agtttcaatg
    22681 atactgcaac ataccaaaaa tatggaaaag gacaaaataa ggataattgg agaagagaaa
    22741 atgtaaatac tctacttaga gatgtaaaag cgtctataaa gagtataaag cctaatgttg
    22801 tatttggtgt aagcccagca ggtatatgga gaaataagag tagtgaccca acaggttcag
    22861 atacatcagg taatgaaagt tatgtaggta catatgcaga tacaagagca tggataaaac
    22921 aaggattgat tgactatgta gttccacaac tttactggcc aattggtctt aaagcagcag
    22981 attattctaa attagtggca tggtgggcta atgaagtaaa aggaacaaat gtagacttat
    23041 acataggaca aggtatatat aagcaaggtc aatcgagtta tggtggacaa aatatagcaa
    23101 aagaaatagt acaacaagta acattaaata gaaagtatag tgaaataaaa ggtagtatgt
    23161 atttctcagc taaagatata gcaaatagta cttctataca aaaggattta aagagtttat
    23221 attctagtag tgaagaacca gttactccac catctaatgt taaagtggag aaattaagag
    23281 gcgacgaaag atatgacaca gcagtagcaa taagtaaaaa aggttgggct acaaattcag
    23341 atacagtagt attagtaaat gggtactcta tagttgatgg tataacatca acaccacttg
    23401 ctacatcaaa tgatgctcct atactattgg taaataagga taatatacct acatccacta
    23461 agaatgagtt aaaaagactt aatccaagta aagttatttt aattggagga aataactcta
    23521 ttggagataa agttgagagt gagataaaag atacattgtc aaatgtatca ataaatagag
    23581 ttggtggttc agatagatat agtacatctt taatgatagc aaaagaatta gtaaaaacta
    23641 atccagtaga aaaactatat ataacaagtg gtacaggtga agcagattct ctttctatag
    23701 cttcaaaagc aggagaagaa aagcaaccaa tagtattagt atcaaaagat aatgtaagtg
    23761 atgaagttta caattggata tcagatttaa aagtaaaaga tgcttatttt ataggtggta
    23821 acctaagtat atctgattca gtaataaata agctggataa ggtcattaca aatgatgtat
    23881 ctaaaaatag aatagctgga gaaaatagag aagaaacaaa tggaaaagta atacaaaaat
    23941 tctatccaaa tgctgaatat tcatcaatgt ttgtaagtaa aagtaatcaa ttggtagatg
    24001 cattaacatc aggtccttta gcagctaaat taaaatcacc agtagttatg cttggaaata
    24061 gtgtaacatc tgctcagaaa actgctttag agcctaagaa aactactcta gtatacgaag
    24121 ctggagatgg tataaatcaa aacacattaa acactttctt aaacttagtt aagtaataaa
    24181 aaagttaatt taaaatacag agtattttat aaatgtagat taaaatgaaa attatcatga
    24241 taaattaaaa aataaaaaag aactatatgc attttgtaat caagtgtaca cagcaacttg
    24301 aaaataatta tgcgatatag ttctttttta gtaattaatc ttatactttt taataaactt
    24361 tatattgaat tttttattgt ttaaactcta tgtcattaaa tataaaatcg tgtaatatgt
    24421 ctaaagtatc tgggtcaaat ctaagaaccc atccagcttt tccatatata ccacctgtac
    24481 tatgaatttc atcatcaata ggaaattcaa attgcttaat atttaagtcg cccattttta
    24541 aaacttgagc tcctaaagaa agtattgcat taggcttcat gttagtttta acatatggaa
    24601 gaactgcatc taataaacct ggatatttag taacaggtaa agtttccgtt ttcttgatta
    24661 tagcttgtat aatctgtctc tgtctgccat ctctagcaaa ggctgtatcg ttgtgtctga
    24721 tacgtgcaaa agatagtgcc tgatatccat ttagagtctg ttttccagag tttctaatgt
    24781 attgtatgct acctttatca tcacttttat tccatttata agtttcagga ataaatttat
    24841 ttagttctcg tatttctcct ttttcaacag taacctcaac gccaccaata gcatcaatta
    24901 tatacataaa tgattcgaaa ttaacacaag cataattttg aatatcaata ttaaaattct
    24961 cttcaattgt ttgtattaat aaatcagctt gtccataagc ataagcatga gtaagttttt
    25021 gtttaccatg accagggatg tctacatagc tatcacgagc taatgatgta agtttgatat
    25081 cattgtgttt gttatcaata gtaagtatca tcatagcatc tgaccttgaa gaatcttcat
    25141 ttggtctagc atctgttccc ataagtagta tgttaattat cccatcttca tttttatggt
    25201 cattgttatc caataaatca ctacttatgc tcgagtcatg aatagcagat aatttataat
    25261 aaaaatatcc atagacactt atagggaata ttactaccaa gaaagccagt agtataacaa
    25321 atttctttaa ttttgacaaa agtacccctt ctttcttctt tttcctgtat attttttaat
    25381 agcatacact taattatatt aaagtattga gatatattca atacttgttt cagttacaaa
    25441 aaaaagacaa tgatataatt tataagaaaa tttatcgacc tatatatata gttaaaagta
    25501 tatataatat attttttaaa agtaatttat attttaaaat aaaaacacac cccataaata
    25561 caaagtaatt tgcatttaag aggtatgtat ttatcatcaa attattggtt tgttttggaa
    25621 tttctaatct tcaaccataa tatctttaaa tatgaaatca tgcattgcat ctagttcata
    25681 ttcctcaaaa ggtattacat agcctgcatt acctattttt ctaccatttt cagtagaaag
    25741 aggaaactcc atagatttca aatttaaatt tcctatactt aaaagttctt ttcctaaaga
    25801 tattatttca ttaggattca tattagtttt tacatacgga agtattgtgt taactagatt
    25861 aggatattta gtgactggta aatccttaac accatttatt aaactctgta taacacttct
    25921 ttgtcttcta tctctttcat ctgtactatc attttttctt atacgagaaa atgcaagtgt
    25981 ctgatatcca tttaattttt gctcaccaga atttcttata tatttaagag aacctttatt
    26041 gtcattttta ttccatttat aagtttcagg aataaattta tttaattctc ttatttcact
    26101 cttatcaaca gtaacagtaa ctccacctaa agcatcaact atatccataa aagagaaaaa
    26161 gtcaactacg gcgtagtttt gtatatcaag ttggaagttt tcttctatag tttctattaa
    26221 taagttagct tgtccatata cgtaggcatg tgttaatttt tgttctccac gtcctggtat
    26281 attaacataa gtatctctat ttaatgaagt tagcttaaga cttttatttt tattatcaat
    26341 agtaagtatc atcatggcat cagaacgaga aacttcttct cctggtcttg catctgtacc
    26401 taacaataat atgtttgtga tattttcttc gtttttatag tcattactac taagcgcctc
    26461 tgtatttata ctatcatctt gtatagtttt taatttagta aaaacatatc catatatact
    26521 aacaggaaat gctataacta aaagggctag aaatataacg aactttttga gtcctgacaa
    26581 taatatcccc tactttctaa attttttaat tacacatagt taattatatt aaaaatttgt
    26641 tacataagca ataaaaaaca caataaatta gcataagttt gtcataatat aattattttt
    26701 atagcatttt atagaagaaa gtgtgtagtt attattgatt ttattggaat ataattgtat
    26761 gaagacttaa atttttataa actgatgtgt atattgaaaa aaatattttc ctgaatgtag
    26821 ttatagcatc ttatgaaagg tgcaaattgt aatttaaaat ttttagtgta taataagaat
    26881 tgaaaattca aaccgataaa aattaataaa aaataattat aaattaataa tttgggggag
    26941 gaaatgtatg ataaaattaa tagcaacaga tttagatgga actttgttag atgaaaagag
    27001 cgaaataaat ccagagtttt ataaagtatt taaaaaatta agagagagag ggataatgtt
    27061 ttctgctgct agtggcaggc agtatcaaaa tcttataaaa aaatttgaag atataaaaga
    27121 tgatatgatg tttatatcag aaaatggaac actagtagta tataaaggaa aagaaatatt
    27181 atcaaatcct ttaaataaag aattagtaaa tgaaatcata gagacaacaa gaagtataaa
    27241 agggaaaaaa attgtaatga gtgggaaaaa atacgcttat atagaaagca aagatgaagc
    27301 gtttatacaa gaggtcagta cttattatgc aaagtttaaa attgtagagg atttgacgaa
    27361 agtagaagga gacatattga agatagctgt atttgacttc aaaggtgcag aacataataa
    27421 taatatctac tttgaaaagt tttctgatag agctcaagta tgtatttctg gagtggagtg
    27481 gcttgattta actgcaaaag gtgcaaataa agggagtgcc ataaaaaaag tacaaaaaat
    27541 gttagatata aaatatgaag aaactatggt atttggtgac cagttaaatg atgtggaaat
    27601 gatgaaaagt gcctatcata gttatgccat ggaaaatgca aatgaacatt tgaaacaaat
    27661 tgctagattt agagcaaaaa gaaatactga aaatggcgtt gtagataaga taaaagaggt
    27721 tataaaaatt ggatagtcat atgtatagat gaaaaagatt attttgaaga aatcaaaaaa
    27781 atatcaatgt aattttgata aataagttta tttatgcgaa aattacattg atatttaata
    27841 aacatcaata atagatattt atttttttat gatattcagt attttgtttt ctatttgagt
    27901 tgcattttca gcagaaatta aataaacata tctacctgcc ttctcaatta tagtattatt
    27961 tgctatttca gaattgattt tttctccatg tccttctcca aaaggtgctt gtatcatatc
    28021 ttttttataa ttttctagag ttttatagat tttatctacc tcgtcagttt ttataacgat
    28081 aatatcttct agagataatt tttcagaaga attaattaca aaaccttgaa ttatgtcttc
    28141 ctctacatca ttaaaatagt taaaatcctt tgcatcaaag atttttgatt cctttataag
    28201 taaatcagaa gattttaatg ctttttttat ttttgatgta gaaacgtttt tgtaatcacc
    28261 acttgaagaa caactaacca ttcctaatga taagattatc gaaaaaaaca atattaaaat
    28321 ttttttcatg ataaacctcc aagtttttta aactctgtct taaattagtt tactacataa
    28381 ttatataaaa ataaatgtat ttaatgttac agttttgatt aataatgtaa tattttgata
    28441 ataataccta ttgagaggtg attagaaatg agaataccaa aacatgtagg aattataccg
    28501 gatggaaata gaaggtgggc aagtcaaaat ggtatgacaa aagataaagg atatgaaagt
    28561 ggaatagatc ctggactaga gtcttataga ttatgtagag atttaggctg tgaagaggtg
    28621 actttttatg gatttacaac tgataataca agacgtccat cagtgcagac aaaagctttt
    28681 acaaaagcat gtattgatgc tgcaaatata ttaatagatg aaggtgctgc tttattagtt
    28741 gtaggaaata caaaatcgcc aatgtttcca gaagaattat taccatatac taatagaatt
    28801 aaagccaaag aaggtcaaat aaaagcaaat cttctggtaa attatggttg gtattgggac
    28861 ttaaataata tatcaggagt agaaaatgta aataaaaata atatacagga ttacatacag
    28921 tcatttgatg tatccagact agacttgata atcagatggg gtggaagaag gagattaagt
    28981 ggtttccttc ctgtacaatc aatttatgca gatttttatg ttatagataa ttattggcca
    29041 gattttaaga gtgacgatat aaaggacgca tttagttggt atgatacaca agatgtcact
    29101 ttaggtggat aattaaaaat attctgattt aaggttgtag agtgttttaa attattgaaa
    29161 aaaaaacttc ttgatggtaa aataacacta ataatatgta aaagtgtaaa aatttatacc
    29221 aagaagggtg aagaaatgtc aaaaggcaat aataacaata attcaagaaa caaatctaaa
    29281 aagaccagtc atctgaatag aaaaaagcga aaattaaata agaaaaagtt agcagtgttg
    29341 atttgcttta cagttttatt tttatttatt gcatttaagg ctactcaagg tgtagtagct
    29401 ttggtaaaaa gtatggataa aagtaataaa actaatcaac aacaaaatgt taactcagaa
    29461 caatttgacc ttggtaatga agaggaaaat aaaaagaaaa aatatactgt atttatagac
    29521 ccaggtcatg gaggcaatga taaaggaact gaaagcaaga ccagtaatag atatgaaaaa
    29581 gacctaaatc tacaaattgc aaaaaaatta gcaaataaat tatctaaaca aaaggatatt
    29641 caagtagtag tatccagaac tgatgataca tatatatcat taaaggatag agctatctta
    29701 gcaaataata gttctgctga tgtgcttgtt tctattcatt taaatgcaga gaaaaatggt
    29761 aatacagcaa caggtataga aacttggtat aggaataaag ctacagatgg ttcaaaagaa
    29821 cttgcacaga cagtacaaag tactatagta tcctatgtta aagttagaga taggggaata
    29881 gttgaaaata actttgaagt acttagagaa tcaaatatgc ctgctatatt aatagagtgt
    29941 ggttttttaa caacaccttc agaggaacaa aaaataataa atgaaaaata tcaagaccaa
    30001 cttgcggaag gaattgttca aggtgtactt tcatacctag attctaaagg gaataagtaa
    30061 gttaacttta ctttaatgtg aggataaatt taaaagttta actgtgtaaa ttgtattaac
    30121 tttatttcgt aatgttgcaa acattgtttg aatttagaaa ctatgaaatt agaaattatt
    30181 ttatctatat ctaatttcat agtttttttt gcaaaaaatt tatagttata aaattttaaa
    30241 aaataaattt agtataatgt aatgtagtta tttatatgtg attttaactt gcattgattt
    30301 gctatcaatt gtgctttata attagtatat ataaagttta actgtaagat aatttaaaaa
    30361 ataggggaat ttatatgaat aaaaatagca tgacaagaat ttacagttta aataaaataa
    30421 tttttattat aattggaatt ttaggaatag ttttactcac aagacatatt gaggtagata
    30481 ttaaagtttt aattttaatt ttattaacct tgtttagtat aaatgtattt atttcatatc
    30541 ttaaaattaa gttgtatgag gataaaatta atttaggatt gataaataat tcagataagt
    30601 ttataaatat tactaaagat gagaacttcc taaaacatgt tcaaaattat attatcagta
    30661 atgaaaaaga aaactgtgta atggcttgtt ttgatttatg tagactcaaa cttataaatg
    30721 atatatatgg ttatgagcta ggggatgaag tgttaaataa tattttaagt aacttaaaaa
    30781 attattttgg aaaagaagct atttatggaa agttaaaaag tgatgttttt gtattaataa
    30841 taaagcttga aaatagggaa cagaagattc cttatttagt aaatcttatt aagaataaaa
    30901 ttgtgatact aagtcagatt gacagtttta aaatggatat aaatattgag gcttctattg
    30961 gaatttataa atttaacaat aatgaaattg atataaaaaa agctatagat aatgctgata
    31021 tggcaaggct taaatcaaaa ggactaaagc acatagagta tgtagaattt gataatgcta
    31081 tggaagaaga aatacaatca attatgaaaa tagagagaga tttattcttg gctattaaaa
    31141 ataaagagtt tgtaattcac tatcaaccta aagttgattc aagtacaggt aacattatag
    31201 gttcagaggc attgataaga tggttgcacc catcattagg catggttgga ccaaataagt
    31261 ttatacctat agctgaaaaa aatggtctga taaacaatat tggtagatgg ctaattcaag
    31321 aagtttttat taccattaac aagtggattt cagaaggtat aaatgtctta ccagtctcaa
    31381 taaatctttc tagagtagaa ctatataaaa atgatttagt tgattttttt aaactgatgt
    31441 ttaatacata taatattcca aaagaactta tagaattaga aattacagaa acgacagcac
    31501 taagagatgt aaaatttata agtgaaaggc tttatgagat taaatcttta ggtatgaata
    31561 tatcattaga tgattttgga gtaggtaatt caaattttat caatcttaag gggataccac
    31621 tagatattat aaaaattgac aggtcactta tattggatat agttacaaat acaaaaacaa
    31681 agtttatggt gaaagcaatt gttaaccttt cacatgattt aaacgtaact gttatatgtg
    31741 aaggggtaga ggatatgcat caggtcaaag tcttaagtga actgggatgt aatttcatac
    31801 aaggttatgt attttttaaa cctttggatg agatgaatta taaaaaactt cttactgacg
    31861 gaagttatat aaatctgaaa gatactcttt tagataaatg catgacagtt gaggaggagt
    31921 aaggatgatt tcagaagatg tagattattc aataagaatc ataagagcta tatttaataa
    31981 tggagaagat aaaccaatag atgctaaaat gatattaaaa agtgaagata taccaatact
    32041 aacactatac agactgctta gaaagctttg tgcaaacaat attcttactt ttaacaaaga
    32101 agatggcaag acatacatgt taaatgtgtc attggataca ataagtctaa gaactattgt
    32161 agaagtaatt gatggaaaaa tatatataaa taaatgtacg agatatgtat ctaattgcag
    32221 taattgctta aaaggttgta aagtaaatcg tgaattgcta gaaatagaaa aagaaattta
    32281 taaactttta tcgagaaaat ctataagaca aatactagaa taaaaaattt tcagctatga
    32341 taataattgg aggttttcgg ttatggatga tatatctcaa gataattttc tactgtctaa
    32401 agagtatgag aatagcttag atgtagatac taaaaaagca agtggaatat attatactcc
    32461 taaaataatt gtagattata ttgtaaaaaa aactttaaaa aatcacgata taattaaaaa
    32521 tccatatcca cgaatacttg atatttcctg tgggtgtgga aattttcttt tagaagtata
    32581 tgatatttta tatgacttat ttgaggaaaa tatatatgaa ttgaaaaaga agtatgatga
    32641 aaattattgg actgttgata acatacaccg tcatatatta aactattgta tatatggtgc
    32701 tgatattgat gaaaaagcta taagtatatt aaaagatagc ttaacaaata aaaaggtagt
    32761 aaatgattta gatgaatctg atataaagat taatctattt tgttgtgata gtcttaaaaa
    32821 gaaatggcga tataagtttg attacatagt gggtaatcca ccctatattg gtcataaaaa
    32881 acttgaaaag aaatataaaa aatttctcct agaaaaatat agtgaagttt ataaggataa
    32941 agctgactta tatttttgtt tttataaaaa gattatagat attttaaagc aaggagggat
    33001 tggcagtgtt ataactccaa gatatttttt agaaagtcta tcaggtaaag atttaagaga
    33061 atatattaaa tcaaatgtca atgttcaaga aatagtggat tttttaggtg caaatatatt
    33121 taaaaatata ggggtatcta gttgtattct aacttttgat aagaaaaaaa caaaagagac
    33181 atatatagat gtatttaaaa tcaaaaatga ggatatatgt ataaataaat ttgaaacatt
    33241 ggaagaactt ctaaagagta gcaaatttga acattttaat ataaatcaga gattgctatc
    33301 tgacgaatgg atacttgtaa ataaagatga tgaaactttt tataataaga tacaagaaaa
    33361 atgtaaatat agcttggaag atatagcaat aagttttcaa ggaataatta cagggtgtga
    33421 taaagcgttt attttaagta aagatgatgt aaagttgaac cttgtagatg ataaattttt
    33481 aaaatgttgg ataaaaagta agaatataaa taaatatata gtagataaaa gtgaatatag
    33541 gctaatatac tcaaatgata tagataatga gaatacaaat aaaaggatac tagatgaaat
    33601 tatagggcta tataaaacaa aattagaaaa cagaagagaa tgtaaaagtg gaataaggaa
    33661 atggtatgaa cttcaatggg gtagagaaaa gcttttcttt gaaagaaaaa agataatgta
    33721 tccttataaa tcaaatgaaa atagatttgc tatagattat gataacaatt tttcaagtgc
    33781 agatgtatat tcttttttta taaaagaaga gtatttagat aaattttcat atgaatatct
    33841 agttggaatt ttaaattcca gtgtttatga taaatacttt aaaataactg ctaaaaaaat
    33901 gagtaaaaat atatatgatt actatcctaa taaggttatg aagataagga tttttaggga
    33961 taataattat gaagagatag agaatttatc aaagcaaata atatcaattt tattaaataa
    34021 gtctatagat aaaggaaaag tagaaaaatt gcagataaaa atggataact tgataatgga
    34081 ttctttaggt atataagcag ttgtaagtat taaaaaatta taatctttta attgtttatt
    34141 taaatttaga aataaaaagt tagccatata aaaaatatta aaaatatata cttttcaata
    34201 tttttttgat aaaataagaa tgaatttgtg caattttatt tttctccaat aactaaaaat
    34261 agttttttga attaatattt gcttaagaat aaaaatcaga aacgtttttg atatagtagg
    34321 tgataatatg aaaggattag ttttagaagg tggaggaaca aaaggagcct accaaatagg
    34381 tgcatataaa gctttaagag agcttggtat agagtttcaa ggagtaactg gcacatcaat
    34441 tggtgcttta aatggagcat atataattca aaatgatatt gaagtaatgg aagatatttg
    34501 gttaaattat gactatactc attttatgaa tattgataga gaaacctatg agaggtttaa
    34561 aaatgtagat ttcactacta aaaatctcaa tgcagtgttt gagcttataa ataaagctag
    34621 aaaaaatgaa ggtatagata taagcccatt aagacaatta atggagacaa cattaaatga
    34681 agacataata aggaaatcaa aaaaagactt tggacttgtt acggtctggt gggataaaaa
    34741 aattaatcca tatccattgt atatcgaaga tatacctaaa ggaagattga ttgattattt
    34801 aattgctagt tccagtttgc ctatttttca aacgaacatg atggatgata agttgtatct
    34861 tgatggaatg ttttgtgata acatgccaat aggactcttg gaagacaaag gttatgaaga
    34921 tgttgttgta attaggttga ttgatgattt tattgggaaa atgaatctaa atcgacatca
    34981 aaatataaat ataaaaacta taataccatc agaatatcta ggaggttctc ttaataaaga
    35041 tagagataat gtagaaaaaa acatccgact aggttactta gatactatga aagcatatga
    35101 aagatgcact ggaattaagt attattttga tgtagagtat aaatataatg aagaatattg
    35161 ttttgataaa tttagaagta tgagcaatga aacaatacaa tatatctgta atttattgaa
    35221 tataaaaaga gatgcttcac ttagaactgt tatggaaagt gtaataccaa agcttggtga
    35281 ggtgcttgga ttgccaaagg atttttcata taaagatttg ttttactgta tatatgaaaa
    35341 gaaacttgaa gaaaataata taaacaggat aaaattatat gattttaaca aggttataga
    35401 tgttgtaaat acaaatattg attctaatag aaatttagct tctaattttg aagttagacc
    35461 taaaattagt attaaaaaga acaaaaacac aaaattattg acaaattgta ttataaaaga
    35521 cataaaaaat caaagttaaa taaaaaacaa aaaaaaattt gtaattatac tcgaaaaaag
    35581 tgtatattag tagtataata tttttgtagc actagtggga acaaaaaatg accataggac
    35641 aaaaaagtac cacttagtac cattaaagta aaaaacagga aaacaatttt aaaaaatata
    35701 aaatgtaaag tttataggag gatttaaaaa aatggaaaaa gtagttagta tcaaaaatgc
    35761 aagtggatta catgctagac cagcaggaat gtttgttaag aaggcagctg aatttaaatc
    35821 aacagtagag gttgtagcaa aagacaaaac tgtaaatgca aaatcaataa tgggaataat
    35881 gagtttaggt ttagctcaag gagaagaatt aaagttagtt gtaaatggag aagatgaaga
    35941 agtagcttta gctgcaatgg ttgaattagt tgaaagtgga tttggagaat agatataata
    36001 attttttaaa aatttgatat ttagaatcta atattactta aagtaaagta acagagaagt
    36061 attaaacata tacagaccaa catttgtaga tatttaattt ctttgttact ttcatgttta
    36121 tttaatcaga agattaagac tattgttaat tgggtataaa aatataaata ttttagaaaa
    36181 tgaaataaga tatttttaat cataaattca gagtaaaaat acagtaacaa atagtttata
    36241 aaattttata aaaaattata agtaaataaa actataaaaa tgtaaattat ttatataaat
    36301 ttataaagtt tatgtgctag atgatatttt ttaggaggta gggttatggc ttacaaagga
    36361 ataggtgctt ctcctggtgt tgctttaggg aaagcgttag tagttgaaca tagtgaatta
    36421 gtaattgaaa aaaaatctat agataatgtt gaagctgaaa ttgctaaatt agaagatgca
    36481 gttgcagttt ctaaagaaga attagtaaaa gttaaggaaa aggcttctga agaattagga
    36541 gcagaggaag cagaaatatt tgaagcacat ttattagttt tagaagaccc agagttaatt
    36601 ggttctgcaa tagataaaat taaaactgaa agtgtaaatg cagagtatgc tttaaatgaa
    36661 ataaaagaga tgtttgttag catgtttgag tctatggaca atgagtacat gaaagaaaga
    36721 gcggcagata taaaagatgt tacaaataga atacttagac atatattagg aattaaagtt
    36781 gttgatttat ctgctttaag cgaagaagtt gtattaatag cacatgattt aactccatca
    36841 gacacagcaa ctatgaataa aaaaatggtt ttaggatttt taactgatat aggtggaaga
    36901 acttctcata ctgctatcat gtctagaact ttagaaatag ctgcaatcgt tggattaaat
    36961 gatataactt caaaagttaa ggatggagat tttgtggttt tcaatggaga cacaggtgaa
    37021 gtaatcgtga atcctgatga agagactata aataaatata ctgaattaaa agctaagtat
    37081 gaagatgaga gaaaagcatt acagctatta aaaggaaaac catctgtaac tttagacgga
    37141 aaacatgtgg aattagctgg caacatagga acacctaacg atatagaagg tctaataaag
    37201 aatgatgctg aaggtgttgg tctttataga acagaatttt tatacatgga tagagattct
    37261 ttcccaacag aagaaataca atatgaagca tacaaagctg tattagaagg aatggatgga
    37321 aagcctatag ttataagaac attggatata ggtggagata aagaattaag ttatttaagt
    37381 atggaacctg aaatgaatcc attcttaggt tacagagcaa taagactttg cctagataga
    37441 aaagatatat ttaagactca attaagagct ttatatagag ctagtgttca tggaagatta
    37501 agaatcatgt tcccaatgat ttcatcttta gaagagttgt tacaagctaa agaagttgta
    37561 aaagaagttt tagcagaact tgattctgaa ggtgtggctt atgctaaaga tgtagaaatt
    37621 ggtatgatga tagaagttcc atctgctgct gtaatatctg atgtattggc taaacacgta
    37681 gatttcttct ctataggaac taatgattta attcaataca cttgtgcagt tgatagaatg
    37741 aatcaaaaga taagttatct ttacaatcaa tttaatccag ctgttttaag acttataaag
    37801 actgttatag acaatgcaca taaagaagga aaatgggcag gtatgtgtgg agaatctgct
    37861 ggagaccaaa aaatgatacc aatactttta ggtatgggat tagacgagtt ctctatgtct
    37921 ccaatatcaa tacttcctgc tagaaagtta ataacttcag ttaaagagtc agatatgaaa
    37981 aaattagctg atgatgtact taatatgggt actgctgaag aaataaaaag ctatatagaa
    38041 aagactttta atatataatt aatgttatat agttactaaa attcattttt ctaaataaca
    38101 aaattatatt ttacgaataa aaaaactata gtatatcata tatactatag tttttttgtt
    38161 atataaatta cgtatcaaaa tttgtaaaat gaatagatat aattactaaa tatgtgatag
    38221 tattggctat aataggatat aaaaaataat attgtaataa aaagtttata tttagtaatg
    38281 aaaatttaac gttttacttg aaattatgtg ttttgtaatg tattattaag gttctaatag
    38341 gaacattttc atcaattttt ctatagtggg ggtaggaatt atgaggtaca aaaaaagaaa
    38401 tatagataag tcaagtgaac tttcatttca atctctagca aaatatttta taactttcta
    38461 tatagtaatt atattaatta ttctttctat gttttgtata aatacaatat gggttatgaa
    38521 aaaagataat caagatttat tatctacaac atcaaatcgt attgaagata gggtaggaga
    38581 aacaattaag ctattgaact ctttgagtaa agataattac ataatagata atagtgtgaa
    38641 tggcatagat aaaagtaaag aactttcaat gtatagtgat gaatttgggt atatgatgat
    38701 atgttttgtt gataagaata taattgtgtg ggatgaagaa ggtggtaata ttagtctagc
    38761 tggtcgtgat tatatgcaga aactttttgc aacaaaaaaa tatcaagtta cagatagttt
    38821 tgcagcaggg gctgatggaa aaactttaaa ctacactatt gcatcaccta taataaagaa
    38881 tggaaatgta gatggttgtg tatttgcagc aatttacttt gatgagataa aggatatact
    38941 caaacaagga aaaggtcaac agcaacagaa tttcatatta tttggaagtg aaaatcaaat
    39001 aatgaattta acaagtgatg aaactgcata tggagagaag tatatgaagt tatcgcagaa
    39061 aacaaaatat cttggaacca atgcaaaaaa agtagaaaag gatatgttta ataataaatc
    39121 aggtgattat tgggcttttg aaaatggaaa attatacttt atgtcctata aaccaattaa
    39181 gaacacaaat tggagtttat tttgtaaagt taatttctta gatatttttg cattaaattt
    39241 aattcctatg ggagctattc tatctgttat aactttagta tttattattt tgatttgtat
    39301 ggagaaaagc ttcatgaaaa aacgaatgga agttattgat atgcttttag gctctgttca
    39361 agaattagaa aaacgtatat atcaaacaga aagacctagt gaagtagact ttaaagaaat
    39421 tattcagctc acaagtaaag gtctgactga tggattaact ggtgttgtaa cacgtactgt
    39481 attttttgac caaatttata atcgtgttga aatggaggaa aatgataaat tatctgtaat
    39541 ttcatttgtt gatttagatg atttgaaatg tattaacgac ttatatggac atgaaattgg
    39601 ggatatggtt ttgaaaaatg ttggatatgt acttcgtgaa tatgagataa aatataatgg
    39661 tttaattggg cgctatggtg gagatgaatt tgttatgttg ttatctggtt ttacatcgag
    39721 agaagaggtg gaggatttat tggatgagat tgctattcgc ttacatactg aagtactaac
    39781 agatgatggt atcattcaaa ctcattgtag tgttggagct gtagtatgta gtgtaaaaga
    39841 caataaagat atagataatt tattaaaaca ggctgatgaa gctttatact atgttaaacg
    39901 taatggaaaa ggtaattatc atttagttta atgtatgtgg aaggagttta tatcatatga
    39961 aaaatgtatc taaaaaattt tttgtatgta ctattattgt attaataaca tttttatgtt
    40021 ttagtaaatt tgctatttat gtttttgaca aacaagaaaa gaaagaaaca aaagtagtag
    40081 aaaacatgtt aaatgtctac aagaataaca ttattttaaa tctgactgaa aaatttaatt
    40141 atagcaaaga cttgacatca gttttagttt caaacaatta ttctatagat aaattaaaac
    40201 ctattgcaga tgaaattctt aaaaacaatt cttgcatata tatttcagtt gtagaaaaat
    40261 ataatgtagc tgcatttttt tctaattctg tcaaaaaaga tattatcaat actccaatac
    40321 aggaactgaa ttattcttat tcattagcaa attctatcaa aggattagtc gtagaaggtc
    40381 cttctaaaga ccagttttca aatggagatg tgtttttaat tactaatcct atttataaaa
    40441 atggagagta ctggggagaa attacagtag ctttagatgc caaaaaagtt gtagattctt
    40501 ttaacttaaa taaattaaaa gaatctggat ttgagtatga actttggcgt gtacacctag
    40561 ataatggttc aaaatctaca atagaaattt ctactaaaga ttttaatttt tccaaatcac
    40621 atgaaattaa gtttaagctt ccgactgttt ggactcttag cattgtgtac aaaaatggat
    40681 ggaataataa gaatatagat tttattgtat ttgttatatt gttaattatt tccatattaa
    40741 taggtgtgat gacatttatt tacattgaaa agaagtcgat tggtaaggaa ttaaatcaac
    40801 agagtcttaa aaatttagaa actggtattt tgaatagaga aggtttttta attaagttac
    40861 aagagcatct gaatagaaaa aataatgaaa tagtattgct gtatatatgt attactaatt
    40921 atagtaaatt tgctccagtt atgagctttg aaaaaagaca agattatctt acacatatag
    40981 taaaaaatct agataattac ataaaaagtt ctcattttat tgctcgtata agtgaggaag
    41041 gttttgttct agctttagaa gaaaattgtg ataaaaatga attgcttaac attgaaaaag
    41101 ggatttcctt agagctttta cgaaaaatta aagtagaaaa taaacaagta tttttaacga
    41161 ttggttatgg ctcatctagg tgtgttgatg atagaaaaga tgcagaatct ctgttacttt
    41221 cagctattga agattatgag agaagatttc cagcaatgtc tcctattcat gattttacta
    41281 aaaagtgtga agatatgctt gatgaaaaga aacagattgt atttggtgaa tatccagatt
    41341 tagaaataaa caagttgtct aaagtaatat acaaatatta taaaaaagta cagcgtatta
    41401 tgtataaaga ttataatatt gatattggaa atagacgagg gtatatgcgt gatgttcaag
    41461 tattaattga ttataattct gagagaatgt tatacttatt tttaatagac atatgcaagt
    41521 ttggaaaatt taatgaactg ttttctattg aaataggaga tgttatttta aaagaagtta
    41581 gtaacaaatt aaaaacaatt ttttctaatt atctatatcg tattaatgga gatgtatttt
    41641 taggcatttc aatagataaa gaatcttact tagatacttt acataaggtt aatgaagtat
    41701 ttaatagttc tttaagtgta gaagatgtac tttttgatgt aaaatgtaat attggtattt
    41761 gtcaatatcc atatcatggt gaaaatccat atgaccttct ggaaaaggta caaattgcat
    41821 tggaatatgc aaaaaaggat gtcaaaagta atgttaaagt ttatgataag gaattgacag
    41881 aagagattta ccatgaaaat aatattatta aggatttaaa aaaaggtctg gaagagcaaa
    41941 cactagaagt ttggtatcag ccaattttta atgttagtaa aaactgttat ataaaagctg
    42001 aggcactaat tagattgaga aataaagagg gcggttatta ttctgcttat gaagttatta
    42061 cttatgcaga aaagcatgga cttattaagg atgtaggtct atatgtacta aaaaaggctt
    42121 gtgatgtaac tacaaaaata aaagataaaa atatagattt tgaacaaatg caattaaatt
    42181 tatctgttca gcagattgta cataagcagt gtgcaaatga catattatca tgtattgaga
    42241 attgtggttt agataaaaag tatatttgtg ttgaagttac agaaacagta cttatggaaa
    42301 cttttgaaat tgtaaatgtt actcttgata aactaaaaaa agaaggcatt agcatagctt
    42361 tagatgagtt tggttctgga tttagtagta taaattatct ggcaaattta cctattgaaa
    42421 atttaaaaat agataaggaa ttagtagaac aaattaccta ttctaaaaaa caatttgaat
    42481 tattaaaaac tatagttcaa attgctaaga ttaatggcat ggatattgta gcagaaggtg
    42541 ttgaaacaaa agaaactctg gatttagttg taacttcagg tgtgaatttg attcaaggtc
    42601 attatttttc agaaccttta agtgaagata aatttattga acttatgatt gaagaataaa
    42661 ggttaataaa ataaagattt aaggtattga aaaataatta aaagtattta ataatagaat
    42721 tagggaagaa taagtttata attaaaaata attgattagt agttaataaa ataaatgtga
    42781 tatccaaata aatcctaaat ctaatttgag ttttaatata gatagtctaa agtttgatta
    42841 ttaaagattt aattgtaagt tgttacagtt gatgatattg attagagatt aaagtttaga
    42901 gtagaaagtt accttaaatt taaaaatgca agataaccca atctaaaaat tataatcact
    42961 cgataggttt aaggatttat ttgtttatta taaataggag ggtgtctcaa aatgaacttt
    43021 ttag
//
LOCUS       DAFAZV010000035        42839 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFAZV010000035 DAFAZV010000000
VERSION     DAFAZV010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 42839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42839
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.035"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..437
                     /locus_tag="KOU88_002591"
     CDS             <1..437
                     /locus_tag="KOU88_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212462.1"
                     /translation="TRNKIYCYTKKILRKYQKGITSGKLTADKFADNILSQDFISSIL
                     NEKIVNETNFKISYRNYIETLINIQNENLSNLRKKSTKTAKCFNISQITQLKNLLSNT
                     GYNLLIPYKYLTARDIEGIVTLINTGSIELGNERIYNYISKV"
     gene            complement(530..700)
                     /locus_tag="KOU88_002592"
     CDS             complement(530..700)
                     /locus_tag="KOU88_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212463.1"
                     /translation="MSSVNFEDLKNKFINSDLDEKIRIYTTTEGLSVEQFKELLKYYP
                     IQHLSKLEKALG"
     gene            complement(889..1110)
                     /locus_tag="KOU88_002593"
     CDS             complement(889..1110)
                     /locus_tag="KOU88_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta-type small acid-soluble spore
                     protein"
                     /protein_id="HBK3212464.1"
                     /translation="MASNNNNNRTVVPGAKEALNQMKLEIANELGMSNYQQVDKGNLT
                     ARENGYVGGYMTKKLVEMAEQQMAGKSNR"
     gene            complement(1194..2420)
                     /locus_tag="KOU88_002594"
     CDS             complement(1194..2420)
                     /locus_tag="KOU88_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK3212465.1"
                     /translation="MKKVVIIGGGPAGMIAASTACEKGYDVTLIEKNHKLGKKLAITG
                     KGRCNITNACEIEELIENVPTNGKFLYSAFYTFTNDDVISMFNNLGVKTKTERGKRVF
                     PESDKAFDIVNALERQLKSKKVNILLNSKVEKIISKNNKIEKVILNDKKEIKCDSVVV
                     ATGGLSYPLTGSTGDGYKFAISQGHTIIDTKPSLIGIEVQESFTKDLEKLSLRNVEIR
                     VFNSKQKKVYSDFGELEFTKFGLDGPIIKSASCRMKDTRKENYTILLDLKPALDEEKL
                     DKRVQKDFQKYTNKKFEKALDDLLPKKLIPIIINLSEINPNTVVHQISREQRKNLVHL
                     LKNLKFTVKRYRPIEEAIITSGGVKVNEINSSTMESKLVEGLFFAGEVIDIDAYTGGF
                     NLQIAFSTGYLAGFNC"
     gene            complement(2482..3414)
                     /locus_tag="KOU88_002595"
     CDS             complement(2482..3414)
                     /locus_tag="KOU88_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBK3212466.1"
                     /translation="MDIQLNILLFFQNLRNPILNFIFLVFTISTEAPLLILITTIIYW
                     CINKKCGQKILFAIIGNFVVNLGIKEFVKAPRPIGIKGLESLRVSTAGGYSFPSAHTQ
                     TATTFWVSIMTIFKKRYLHLIGAVMVLGVGLSRLYLAVHWPIDVIAGWILGIFFTVVF
                     VKIFDYIDDNKNYILLVVLLIPFIIVAIFLNSPEYFEKFGIIVGFVFGYMVEDRFVKF
                     NTDNNNKKINFSNKNKGSKNIIFSRICRFLVGIVTIGMLYIGIKLFISMLIVTLNISD
                     STMSIIFMNFIKNTVVVFYGIAGAPALFKLLKLN"
     gene            complement(3503..4030)
                     /gene="hpt"
                     /locus_tag="KOU88_002596"
     CDS             complement(3503..4030)
                     /gene="hpt"
                     /locus_tag="KOU88_002596"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBK3212467.1"
                     /translation="MYKVTGKMLTEEQIKEKVYELGKKIEEDFKGEDLLVVGILKGAS
                     VFVSDLIRCIDLDVNIDFMSVTSYGNSTESSGTVKILKDLDVDIEGKNVLIVEDIIDS
                     GLTLSNLVAALKTRNPKSLKLCTLLDKPQRRKANIPVDYVGFVIEDKFIVGYGIDYAE
                     KYRNLPYIGIVEDVE"
     gene            4259..5335
                     /locus_tag="KOU88_002597"
     CDS             4259..5335
                     /locus_tag="KOU88_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003415975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBK3212468.1"
                     /translation="MSTNHGANLYSLSSKYGFSKEEFMDFSSNINPFGTSSLAKQYIV
                     NNIDMVSMYPDPDYIDLKTSISNYCKCSIDNIVLGSGATELISSFIHTINPKQALLLS
                     PAYSEYEKELSKINCSIEKYFAKEEDNFHINLENLIKTINAKDYDLVVICNPSNPTGF
                     AFTKVEVREILKNTDSFLMIDETYVEFTDTDTYSCTQLVDDYSNLFVIRGTSKFFSTP
                     GIRLGYGLISNTNVKNEINKNLDLWNINIIASKMGEIMFSDLDFISNTISLMNTERDY
                     LLKELKNIKSLDVYNTKGNFILCKIKTKELTAKSLREQLLPQKIIIRDCCSFEGLDEY
                     FFRVCILKPNENKLLISSLKAIFK"
     gene            complement(5421..6629)
                     /locus_tag="KOU88_002598"
     CDS             complement(5421..6629)
                     /locus_tag="KOU88_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBK3212469.1"
                     /translation="MKKKIGLVPKLIIGIIVGILIGSYAPEIIVQILVTVSTLFSAFL
                     KFVIPFIIIGFVTAGIADLATGAGKLLGITTGIAYGSTLIAGLLSFAVSTLIFPNFID
                     ASVASQIGDPEAGMLAPIFTIPLEPMVDVTAAIVFAFVMGLGISALRNHGKGETLFNF
                     FQEFQGIVTKTLSTVIIPLLPLYIAGTFANITIAGEVWTILGVFWKVYLVVIPLHFVY
                     MACQFTAAGVFSGKNPVRMLKNQVPGYLTAIGTQSSAATIPVNVGCAEKNGVSKQIRE
                     FVVPLCATIHLSGSMISITGFTTAVLMMNGMPHGIGVLFPYIAMLGIAMVAAPGAPGG
                     AIMSALPFLPMVGIPSDGGLASLMIALYLTQDSFGTACNVSGDNAIAVVVDKINDGMS
                     KKGNKEEQSA"
     gene            complement(6790..7179)
                     /locus_tag="KOU88_002599"
     CDS             complement(6790..7179)
                     /locus_tag="KOU88_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1232 domain-containing protein"
                     /protein_id="HBK3212470.1"
                     /translation="MEFLKIIINIVLDILKKILVRFKNAKFGLVFVFDLLKLPDFMTD
                     KRINIVDKIKVISVLIFTISYFVSGVDIIPEMIAGAFGFIDDAIVLIWSIGIVNEEIN
                     KYRVIAKKDKHSNIIENVEFSIKDEEE"
     gene            complement(7283..8284)
                     /locus_tag="KOU88_002600"
     CDS             complement(7283..8284)
                     /locus_tag="KOU88_002600"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBK3212471.1"
                     /translation="MSTIIPKDYKSSLNVIDTQIAIKKLKDFFEMRLSNELNLIRVSS
                     PLFVLPETGANDNLNGEKAVSFDIPFMNKNAEIVQSLAKWKRLALKKYGFEVGSGLYT
                     DMNAIRKNEELDNIHSLYVDQWDWELVIDKSSRNEKTLKDVVKRLYGVFKDTEIFVCS
                     MYEGIKEILPEEITFITSQELEDMYPELSPKEREDKIVKEKKAVFITQIGKTLISGEK
                     HDGRSPDYDDWELNGDILFYNPVLDSALELSSMGIRVDEESLDRQLKLAGCEERKEFD
                     YHKMLLNGELPYTIGGGIGQSRICMYFLQKAHIGEVQVGVWPQDMIQNCSSAGIELL"
     misc_binding    complement(8343..8598)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(8732..9922)
                     /locus_tag="KOU88_002601"
     CDS             complement(8732..9922)
                     /locus_tag="KOU88_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3212472.1"
                     /translation="MSKYNFDRVIDRVGTDCVKWDFRTNCSTKAQKDGLPFWIADMDF
                     ECAEPIIEALRKKVEHKIFGYSSNDSDKYFNAVCDWYKRRFNWEINRKDIIFSPGVVP
                     AVAILVRILTNSNEGVIVQKPVYYPFEAKIKSNNRDVVNNPLIYENGTYRMDYDDLEE
                     KAKCSNNKVLILCSPHNPVGRVWREDELKKVVEICKKYDLWIIADEIHSDLIRKGFKH
                     TPLQSLCPEYKDKIVTCIAPSKTFNLAGMQLSNIIANNDELKKKYQEEVTAVGVATSP
                     NPFAIVATIAAYNESEDWLNELNDYLDNNIQFIDEYLKENLPKVKLVYPEGTYLAWLD
                     FTAYGLNEVELEDLMFKKANVLFDEGYIFGKEGIGFERINVACPQSLLKECMDRLKTI
                     FENL"
     gene            complement(10203..11324)
                     /locus_tag="KOU88_002602"
     CDS             complement(10203..11324)
                     /locus_tag="KOU88_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HBK3212473.1"
                     /translation="MGTNKDYIEYVHKVYDYLHTIPEKGFEEYKTSEFVLKELEKMGF
                     ENINKGVAGTGIIVTIDSKKEGPVFAIRADMDALEFIIDGEKKMIHACGHDGHTSMLL
                     TAAKLIKERNLVKRGKLKILFQPGEEKLYGALRVIDSGLLDDVEEMVGMHLRPGQDCR
                     LGKAIPAMYHCASCIMEFTIKGITCHGSKPHLGVNAVDAVCLAVNAINAIRVNPAIPN
                     SIKVTNISVKGETYNNIPDEAFMALDIRAESNDIIEELKEKAIHAVKTVVSSINAEAV
                     LISKDGVPAAEFDEELVNLAEETIKDVLGADASIGIFKNSGGEDFHYYTQKLKCKTTY
                     IGLGADATPGFHNPNVTFDTKALEYGVDIWCRLVEKRLG"
     gene            complement(11385..11870)
                     /locus_tag="KOU88_002603"
     CDS             complement(11385..11870)
                     /locus_tag="KOU88_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBK3212474.1"
                     /translation="MSEVAKKEVKVKKGNVIDAFIGGARNGFQISTNSMAPNVIFGFA
                     IISVFNLTGLLDVIGTIFTPVMSIFGLPGVAATAIMTIFISMGGASGVIAGLFTAGQI
                     SQAHVAILLPMLLLSGAQIQFMGRLLGTAELKTKYYPHMFVIATLNGCIAMLIMNYFV
                     V"
     gene            complement(11872..12540)
                     /locus_tag="KOU88_002604"
     CDS             complement(11872..12540)
                     /locus_tag="KOU88_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212475.1"
                     /translation="MSKLESTTEKVEVKWYGYVALILGALFFSGIFKDAPGPLKVLDF
                     NNVLGSFGTLGTINDGVGTLAANFRGDGGTGPRDGWLYALTLIPSVMFALGVVRVIDH
                     LDGMKAAQKLLSPLLKPLLGLPGFAGLTLIASLQSTDAAASMTKELKDDGYIDEKQKA
                     VFCAFQFSGASAITNFFASGAALFPFIGDVPIFIPLALILIMKFVGANLLRLYLNKFD
                     KGEA"
     gene            12930..14954
                     /locus_tag="KOU88_002605"
     CDS             12930..14954
                     /locus_tag="KOU88_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3212476.1"
                     /translation="MDKKKLILITYDKLNSDHYKEELTNFFGDEIIIETQNILDGIKE
                     NLEGDVVLSLSPLTSNFLIKHFKEDIEIIHGTKALSKLGYEKMMKLPPGTKLLLMTTN
                     KTSAFEMATYLYKIGINHIDFVPTYPDCDEIYDLDTAITPGQIRFIPKYIKNIVDLGW
                     RKISLDTYMSLLVVLKLKNEKFIEKLYKLSKETLSHDFLNTSLDNISKLKTILYMTID
                     EIGDGLIFFNTFNKVTFVNKSLLNMLELDEKLIKSPSLMEYMPKSFLDKITKNLNIDN
                     MIIYIDEIDKKFILSKKPFYLYKNIEGCLITLKDVNNIEILEQKIRSDSVKRGYVAKY
                     KFNNIIGNSSIIKDCIKKAKKMALTDNPILITGETGTGKEAFTQSIHNHSNRKNKPFV
                     AINCASLPSELLESELFGYEDGSFTGAKKGGKKGLFELAHTGTIFLDEIGDMPHDLQV
                     KLLRVLQEKEIRKIGGTSIIPIDVRILAATNKDLEKLIIENKFRMDLFYRISMFTLDL
                     PPLRKRLEDIPLLLESFLKELPYKNIKLDKSLLEALNSYTWMGNIRELRNCVEYMAYM
                     GSNYLTINDLPQNISSKLNNNHMSSNMSIFNDLNQYDKNICISILKSLHMKPMGRTKL
                     MKFMEYNVTEYEVRNMLEYLTRNGYLISSKGRKGSSITEKGIKIIENNII"
     gene            complement(15184..16371)
                     /locus_tag="KOU88_002606"
     CDS             complement(15184..16371)
                     /locus_tag="KOU88_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3798 domain-containing protein"
                     /protein_id="HBK3212477.1"
                     /translation="MLRKITAFMLSICLIIGLTGCSLLVGKKDKEKIIDDFKVAVVTQ
                     PLSENKVQYNMVEEMAKEYEEENKIDKDKDGQTKVKQTIKHVVLPENFTSNIDSAINK
                     IVKLADDKEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNL
                     GVSAEERGKVLAERSKEMGAKAFIHYASTDDLKDVNIAKRLEMIKETCKNIGLPFVQV
                     NTPNINTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGVNEYMDEVILTKALELKYIVA
                     EQSNPSPIQTYPSVMGLKISEKDAQNYDKINDMISEKAKAFGMSNRLGGYPMPMDAFL
                     PSVAIYLATEMVKQDLTQEDVCDPDYLEAFTELRFGIGSEFTPLTEVLYNYQSVILSQ
                     LIY"
     gene            complement(16573..17844)
                     /gene="brnQ"
                     /locus_tag="KOU88_002607"
     CDS             complement(16573..17844)
                     /gene="brnQ"
                     /locus_tag="KOU88_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBK3212478.1"
                     /translation="MRDIFIVGFALFSMFFGAGNLMFPPFLGMESGKDWLIPLIGFVV
                     ADAGIAMLVIIATARCKGSMDDVLRRAGKGLARVMSVAALACLALLVIPRTCATTYEM
                     GIMPIFGDHGPVAKAVFSIIFFGLTLAFTIRSSKVIDIIGKYLTPALLLVLFVLIVKG
                     IISPAGPMSPEHMIDKNLFGEGISQGYQTMDALGAASMATIMLMSIIAKGYTSDKDQI
                     GMTIKAGFVACVFLAVVYGGLTYLGATVSTLYDTSIPQASLLVEITSILLYGQVGKVI
                     LGVIVALACLTTSTGLTASISTYFEGISKASYKQLVIGICVASMLISNLGVDSIIAIS
                     VPILQTIYPVLLAIVVMELAGKHIKNDNAFKGAAYVTLVISLLSAINGMTGAVPFIQS
                     LPLAGLGFNWVIPAILGGIVGNFIKSNKQVA"
     gene            complement(17985..18638)
                     /locus_tag="KOU88_002608"
     CDS             complement(17985..18638)
                     /locus_tag="KOU88_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBK3212479.1"
                     /translation="MTKIIKVQKPKFTGELEIIENLEDILEDIFNDEKIFNKIIENEV
                     ISDLDSVRVSFESCIFRNVSFENCNLKKIDLLDVVFENCNLSNTFFDGGSIYRVEFKN
                     SKLIGVRFDDCILKNVLFKDVLGKYSNFSFSKFKIVSILDSNFENSVFQEVKGDNLVF
                     EYTNLKKANFNGTKLSGIDFTTNNIEGIEIGIDDIRGAIFDVSQAIDLTKLMGIIIK"
     regulatory      18967..19068
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            19141..20484
                     /locus_tag="KOU88_002609"
     CDS             19141..20484
                     /locus_tag="KOU88_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBK3212480.1"
                     /translation="MVPNTNNVQPGGNNSSLSFLDKMFKFSERGSSLKTEVIGGVTTF
                     LTMAYIVFVNPAILSEAGMDKAALITVTILATAIGTLIFAILGNAPFALAPGMGLNAF
                     FTYSLVIGAGIPWQTGLGVVFLSGCVFFTLAVTGLRKTIADAIPRELAVASSAGIGLF
                     LAFVGLKNMGVIIANPDTIVSLADFTPTVLIALFALILMAILEYKKVKGGILISIVVA
                     TIISVIFGFVELPTAIISTPPSIAPVAFKLDIVGALKFSLIGPIFSFMFIDMFDSLAF
                     LITCCKQMGLEDENGEIKDLGRMLYADVSSTLIGSFLGTSTVTTFGESASGIAAGART
                     GLASIVTAALFLATLIFTPLLGIVPTYAAAPALVMVGVFMFESIKQIDFADSKIAVPA
                     FVTVLLMPLTYSISIGLCFGFISYIIMHVVAKETDKISITLWIIGLLAVVNLVLS"
     gene            20663..22027
                     /locus_tag="KOU88_002610"
     CDS             20663..22027
                     /locus_tag="KOU88_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3212481.1"
                     /translation="MSQLLIKNAYLITMNADREVYENGSILIENNIIKEVGKFDINIV
                     DKDAEIYDAKGKILMPGLVNTHVHLSQQLGRGLADDVVLLTWLRERIWPYESSFNYED
                     SLISSTACCVELIKSGVTTFLESGGQYVDAMVEAVDKTGLRACLAKSVMDTGDGLPEA
                     WQKTTDEEINTQLDLFHKFNNTSNERIKIWFALRTIFNTTEELLVRTKELADKYNTGI
                     HMHIAEIADEISFVKQNNGVGTVEYLDKLGVLGPNLLAAHTVWLTHKEIDLFRLHDVK
                     VSHDPGSAMKVVLGFASIPEMLEKGIPVSIGTDGAPSNNRMDLMRDMYLTSLIHKGRT
                     LNPTVVPAEEVLEMATINGAKCALLEKEIGSLEVGKKADMIILNPDTIHCLPMHNPIG
                     NIVYSMTSENVDSTICDGKWLMKERKVLVVDESELLNKVKKQASKIKDKAEVKIPSKF
                     KIIK"
     gene            complement(22205..24070)
                     /locus_tag="KOU88_002611"
     CDS             complement(22205..24070)
                     /locus_tag="KOU88_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIRAN domain-containing protein"
                     /protein_id="HBK3212482.1"
                     /translation="MENVFKRLQEFNGYDGYKESFEMNYLCIYESIPLREQVELANNL
                     VDEILNMYKSESNEIYLLEGSNSKSLICYFEIFMKKINTLVKEMIIDEKWLYKLTKEL
                     IYKSKKVEYVKLGLVLSEKYLNVENLREVVDTFSKSGEYVFYLSNTIKKLEFYNTYLF
                     NLSKKATGSIKVFAIVNMENLDSKINSYLIEDGYKDTKYERLLMNYIISIVDLNEYLE
                     KRDLDKEKINNLARLICNYLLSVEFKYIGNKLELVNRFLPTVVNYGTNFESLYSIFLI
                     AINVLKDENIECNKIEFEKEINGILLSEKWKNIYFEALRDASGKTEDIIKMSEIYDVN
                     LSFDDLLPYLNRDIRDFEVYWHISKKGTTSSRLKLLNFFEETFKIDDLIGKMKDIEKD
                     KLTQEYYDDMLFFIVLKGSKSLYPEGKNISLKGIFGNINEVRKESINILKRYREKLSL
                     EELKIVKEAYEKEKNVILKDELRRVLYESNNLKKEFVNIEKIKVDEHGKDIYLTSIAV
                     AGSRFRNREYLEKELEKSKIYYLTREKDNLYDEKAIKIVGETGYVIGYVPRKENYILS
                     NLLDGGKLLYCRVTEYNLYEDCIYANVYLSYKDVIETVENSLKMVLDKSRIKLIN"
     gene            complement(24306..25523)
                     /locus_tag="KOU88_002612"
     CDS             complement(24306..25523)
                     /locus_tag="KOU88_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3212483.1"
                     /translation="MNNKKYYPTAIALYFSYFLLGIGISILGQYKPEFSSMWGAKTLS
                     DGTLDVSIVLAVIAALGLGRLISYPFAGPISDKYGRKVSGLIGNFLHAIFFVGIVFSP
                     NFYIAYVFAIIGGAANSFLDTCVTPSCMEIFASLGTIANMFTKFTIALAQFLLPFIIG
                     FVAANSISFKVIFIVTAILIVVDAFLIAVLPFPPANNVIDNKGKTVKSEKMKFTPTSI
                     ALVCIGFTCTSTFVLWLNCNQELGKLYGMADPTKIQSFYSMGVICAVLITSLLIKKYI
                     KPIRILVIYPIIALLMLLVVYFVQTPTICMLGGFVIGYSAAGGVLQLTTSTANEMFPT
                     NKGKITSIVMIASSIANYVILNIAGIITKSGGVNGPKYVVLFNVAITFVGILLALFVN
                     MRYEKEKVYDYDV"
     gene            complement(25723..26586)
                     /gene="aroE"
                     /locus_tag="KOU88_002613"
     CDS             complement(25723..26586)
                     /gene="aroE"
                     /locus_tag="KOU88_002613"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBK3212484.1"
                     /translation="MEISGRTGLFALIGTPVGHSKSPVMYNYSFKKLDLDYRYLAFDI
                     TVDKVKEALLAIKTFNIKGANVTMPCKSAVTEYMDELSPAARIIGACNTIVNDNGKLV
                     GHITDGVGYVRNLKENGVEVKGKKITIMGAGGAATAIQVQCALDGAREISIFNPKDDF
                     YKRAEQTVENIKKDVPECVVNLYDLEDTNKLYEEIQSSDILTNATLIGMKPYDNETNI
                     KDTSVLRKDLVVTDVVYNPKKTKMIEDAEANGCKAIGGLGMLLYQGAEAFNLYTGLEM
                     PVEEVNELCFK"
     gene            complement(26668..28590)
                     /locus_tag="KOU88_002614"
     CDS             complement(26668..28590)
                     /locus_tag="KOU88_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK3212485.1"
                     /translation="MKISSMFTPIRIGSMTVPNRFVVPPMGNNFANTDGTLSETSKAY
                     YLERALGGFGLITIESSVVDKKAKGGPRKPCLYDDSTIDSFKNVIDACHDAGSKVSIQ
                     LQHAGSEGNEKVAGHPLKAASAIPASNGRNTPLAITTEEIYELIESYGDAALRAQKAG
                     ADAVEVHCAHGYLVSSFISQRTNKRVDEFGGCFENRMRLPRLIIENIRKKVGNSLAIL
                     CRINSTDDVPGGIDVHDSSVIAAYLEDCGIDGLHVSRSIHIHDEYMWAPTTLHAGFSA
                     ELVTEIKKAVSIPVITVGRYTEPQFAELMVRQGRCDLVAFGRQSLADPEMPNKAKNGK
                     LDEMIPCIACLQGCVPNMFQGKPIACLANPILGHEAELKPAEISKEVLVVGGGVGGML
                     AAWVCAKRGHNVTLVEKSEVLGGQMRLAAYPPGKGDITNLVRSYISKCNQYGVKICTN
                     TEATVELIKEKSPDVVIIATGATPLVLPIPGINDSGLIHAVDLLDGKKSCGKKVLVVG
                     GGMVGCEVAAFLGEQEHEVTVIELREEVGADVISEHRKFLMNDFENYNIHTITGAKVS
                     KFYDDGVDYLLTDGTEHDLKGFDSVVLAMGSRNYDPLSEVIKEVVKETYIVGDAVKAR
                     RALDATKEAFEVALNI"
     gene            complement(28654..29502)
                     /locus_tag="KOU88_002615"
     CDS             complement(28654..29502)
                     /locus_tag="KOU88_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBK3212486.1"
                     /translation="MNNQKNLNIPITISSYTLGTEVSFRDRVRIAKEAGFDGIGLRAE
                     NYIDAKNAGVTDEEMIAILNEYDMKVTEVEYITQWGREEDRTEAQREKEQNVYHMAHL
                     FNVKHINCGLLEMIPEEQIITALGELCDRAGELIIGLEFMPYSGVPDLATAWRVVKGC
                     NRENAMLILDTWHWARAKQTAEDLAPVPADKIVSIQVCDVLETPYEKLRDESLHDRLA
                     PGEGYGNTEEFVKIIKEHNISPRVIGAEVISDSLISKGLSTAAETVFNATKKVLDKAW
                     SEVSPK"
     gene            29915..30796
                     /locus_tag="KOU88_002616"
     CDS             29915..30796
                     /locus_tag="KOU88_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3212487.1"
                     /translation="MNLYHLRYFVTLAHLEHYTKAAENLSITQPSLSHAISLLENELG
                     VALFEKEGRNIVLTKYGKIFLKDVEKSLEILDSSVKSLKITGTGEGQIDLAFLRTLGT
                     DFIPDIVHKFLKSNPAKSIDFKFHTGVTTDIIQGLKERKYDIAFCSKLEKEKGIEFIP
                     VAKQDLVLIVPYSHPLAAKDTIDLKETIPYPQIVFNQRSGLRYIIDDMFKKINQQPNI
                     VYEVEEDQVIAGLVAKNFGIAVVPNMNMLSFTKVKVIQIIHPSWERNFYLAFIKDRYL
                     PPAIKNFKNFVIKNAQL"
     gene            complement(31004..31867)
                     /locus_tag="KOU88_002617"
     CDS             complement(31004..31867)
                     /locus_tag="KOU88_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004455022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBK3212488.1"
                     /translation="MLSSYVKRVSKIIKKKYIMFIDESGRADINHEDPFTLTGVIFEY
                     KYAVSQGDYVCSLRKEMDAFKEYCFGTSNIGIHLTDISRKSRAFEKFDDSQIKLFYDE
                     LPLFLSRLECTIISVTVDKARLKKYYAPSKEPYVVAFIHVLQNFYSFVNNETVESARI
                     VIESRDDVSNLKVQKAFFDVFNNGTIYLDIDEELRDKVKGFIIAKKEDADYREGLEIA
                     DILCNPLSRARRGLIEANPKCMQYGEKNKIFKSVRNKIYTPTSVNDIRNWGFKEVPIV
                     EPVGPWLEKMR"
     gene            complement(32022..33956)
                     /locus_tag="KOU88_002618"
     CDS             complement(32022..33956)
                     /locus_tag="KOU88_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp22"
                     /protein_id="HBK3212489.1"
                     /translation="MKKSLKKYLVLALTLVLVFACGVPESSAASKHVIIVNSRKNTLG
                     YFVNNKLVKEFRVATGKKGSETPTGKTKVVNKIKNRPYYKGNIPGGSPRNPLGDRWMG
                     LALKGTYGDTYGIHGNNNESSIGKHISGGCIRMHNKDVRWLFDQVPVGSDVIIDYSND
                     SYVKIAAKYKINLNQTGWKTENGKKYYVKSDGTYQKNSWLKVNGKMYYFDASGVMQTG
                     WKTINNKKYYLGTDGARVSGWKVIDGKTYYFNSDGVMQTGWQEKNGKKYYLGSDGLAV
                     TGWQEIDGNKYYFDKTGIMQTGWQQIDGKSYYLDKDGKMLTGSQKIDGKDYTFNEDGT
                     INPTWDTIIGANRFDTAKKISSVGNWNADSSDTVILVNGNAIADGITATPLASSYDST
                     ILLTNTANLPTETVEEMKLLAPKTVILIGGENAISSKLEQEIKTTFNTETKRIAGQDR
                     YQTATRIAEELGNREEIKTAYMVSGNGEADALSVASKAGEEKQPIILVNKDGITEESY
                     KWLTERKLENAYFIGGPSAINDSVIAKMNDITTEDISGNRIYGDSRVDTNAKVIEKFY
                     GDTDLQAVLVSKSDALVDALSAGPLAVKLHSPIVLMDNSGLSSEQQRVFANKKVETPY
                     QIGGGVSYIVMDKLMDILAK"
     gene            complement(34068..35081)
                     /gene="galE"
                     /locus_tag="KOU88_002619"
     CDS             complement(34068..35081)
                     /gene="galE"
                     /locus_tag="KOU88_002619"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBK3212490.1"
                     /translation="MAVLVAGGAGYIGSHTAIELLESGYEVVIVDNLSNSNSIVVDRI
                     KELSKKPVKFYNIDIRNKDEMHVVFKENNIESIIHFAALKAVGESVEKPIEYYSNNLI
                     STLNLFELMREYGVKKFVFSSSATVYGDPHTCPILEDFPLSVTNPYGRTKLMIEQMLV
                     DISKADKSLDIALLRYFNPVGAHKSGRIGEEPNGVPSNLMPYITKIAVGKLKELSVYG
                     NDYPTHDGTGVRDYIHVLDLAAGHVKALQKLEENPGLVVYNLGTGKGYSVLDLVKAFS
                     KASGKEIPYKIVGRRAGDVAMCYADSSKAEKELGWKAKYELEEMCEDSWRWQSMNPNG
                     YEE"
     gene            complement(35105..35974)
                     /gene="galU"
                     /locus_tag="KOU88_002620"
     CDS             complement(35105..35974)
                     /gene="galU"
                     /locus_tag="KOU88_002620"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBK3212491.1"
                     /translation="MTVKKAIIPAAGLGTRFLPATKSQPKEMLPIVDKPTLQYIIEEA
                     IESGIEEILIITGRNKKSIEDHFDKSVELELELEQKGKTEMLEMVRDISNMVNIHYIR
                     QKEPKGLGHAIYCAKSFIGDEPFAVLLGDDIVDSDVPCLKQLIDTYNEYKTTVLGVQK
                     IAKEDTNKYGILDVKHIEDRVYKVKDMVEKPAIEEAPSDIAILGRYIITPAIFSILEK
                     QTPGKGGEIQLTDALQTLGKQEAIYAYNFEGRRYDVGDKIGFLEATIDFALKRENLKD
                     DLMDYMRKKVSEK"
     gene            complement(36172..36492)
                     /locus_tag="KOU88_002621"
     CDS             complement(36172..36492)
                     /locus_tag="KOU88_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212492.1"
                     /translation="MSSKYNVWTFNYEFLGLDSGDEKNNEVYYEIDLDEILNENYIDE
                     DIDSGLDSDGNSILGELISEMDIDEDVSVDMTYQELEVDLEDLDSYLDEDIDSDIKGI
                     LDEI"
     gene            complement(36482..38473)
                     /locus_tag="KOU88_002622"
     CDS             complement(36482..38473)
                     /locus_tag="KOU88_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212493.1"
                     /translation="MLKLGEKIIYELSDGFELSGISRYSKEYKKLHITNLGNIIISKS
                     DEVNEDTGVKYIYSFSDNKEKLEAVLEDSQIIVYGNNLPFYIKSENSSKNVTANLTMK
                     ITLDEYDLICKSQREFIFYLKDNMTILSLDDNKFYMGGINKDNEKFIFISGKNRFEIN
                     FDDIERYILEDKRVSLKGYFHMEREGIIVRSVSIFNNNIDSVVPSDLNERVKDNQKIG
                     NLPKDCEIVFCKISGNIDGFDYKNTNMLLVKYQDQLIFINKKSKKTIVKSAKDNCSKL
                     NLGEDIILYDNKNVFNLHINDKNREIMQIDDLKDIENEIVGYTLKHAPFFIQEDFDSL
                     TILKSFQKEIISIKNSDIKDIVINKELENENSNFVETEIKFNNQKVLLNLSKSMVQKL
                     MQDVFIYAKQPLLKENSIEVIYKNWSKAMNDMIIFNFFGNIYYMKSEFDKILEKELND
                     EIRIEVINSLYKQIQEQRNNLDLLSAYMPRILENQEIDLFEKYNTKLDVQVFKQIKNL
                     LSDLSYNISSYLNEVEKSLDNIIFVISGEDKKKYNYRMLKESESASLDVFLKQAISRL
                     NHLVENMYPYYVDETSREMFKLFELLWKNYRNIDDDSIKEILFERITNTYVFKQLTLN
                     NSTKERRKDIIEKIYNSVDYGTNKLDENMFFTGGIKYVK"
     gene            complement(38596..41139)
                     /locus_tag="KOU88_002623"
     CDS             complement(38596..41139)
                     /locus_tag="KOU88_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPOR domain-containing protein"
                     /protein_id="HBK3212494.1"
                     /translation="MKVLSENNIIRNTVLNVTASFLKQESKINEKLDGVLEKKFEKVE
                     FNEAKYAELLKFNILFYKTLARNTEPLIGKWIVDKYIPEIDELEKDLELTTAKCRKYV
                     NKAMKEGLDSLKANDLNSFLAYDKMELSERRRRLEKDYKVLNLYKDLLNISLRKISLE
                     KKECGDLFLKNQADAKRELKREIIFCVNKILASNKDVVPNNVEENNEQNKVEIKATEI
                     EDLQLGKDNSENDMLLNEIKNSKVKHESKSNDIESKFIDKLNSLNNESISQTIHNEYK
                     KLCGLEELHSVEAYGFGKEIIKDFACATVVLEFLKRRNRDLIEGAMRLTIIGEFGPEN
                     FKEFVDYVIKNKTEISEDTWNKAQNLIKDNYSELENHEIASKRTRRNKDIDIEEYIYM
                     IKNADKDICFRSSISIEDDAEEGTKEEVDSNNQDIGDVVEDKDTTDKEYDSNKEDIIE
                     PENKKSKKKAKLFGFIKKDNEEAEQEEENLNDISPDIILDKPVENHQVKSEEIEQNEL
                     KEIKQEEPSQHIEEERSVKIEKPINNNLDEKVSSNNESKLEKESKNLEDKKAKEIKEE
                     KLENEKSVVIPIKKKENSNKKSKNSSKDKYRENKKEMKNYVSDKEDSLDDEEVVSKKS
                     RLKETIIAVVIVVIVGVGYFITVGNNKKNDKENIPKSSTQQQANNKLTEEEKKAQAEK
                     EKKEAEEKAKAEKEAQEKAQAEKKAKEMEAYKDGKGVYYTVYAGSLKVEKTAKETAKE
                     YEAKGISSTIIQENGYYKIKIGDYSQYGEAQEKCNELAKKSIDTYIAMYDKYYDYKLE
                     ELKESAPSLSAEELKQKYEDLRSELKNKSGYREYVKHLDKLYEEIVEGA"
     gene            complement(41417..41751)
                     /gene="rnpB"
                     /locus_tag="KOU88_002624"
     ncRNA           complement(41417..41751)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="KOU88_002624"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            41883..42560
                     /gene="srtB"
                     /locus_tag="KOU88_002625"
     CDS             41883..42560
                     /gene="srtB"
                     /locus_tag="KOU88_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtB"
                     /protein_id="HBK3212495.1"
                     /translation="MKKLYRIVINIILVLVILYSGFNIYSKLTKYNHDTKISSELQKK
                     EYKKEDLSKINSDFKFWLSVENTNINYPVVQSKDNSYYLDKDFYKKDSISGTLFMDYR
                     NKSIDDKNIIICGHNMKNKTMFNNLNKFKDADFFKKNNKIKITLNGKEFLYDVFSAYI
                     VESDYDYLKTNFNNESDYQNYINDITSKSLYKSPIKVNSNDKIVTLSTCTYEFDDARM
                     VIHGRLI"
     gene            complement(42720..42794)
                     /locus_tag="KOU88_002626"
     tRNA            complement(42720..42794)
                     /locus_tag="KOU88_002626"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(42760..42762),aa:Thr,seq:tgt)
BASE COUNT        14164 a         7358 c         4757 g        16560 t
ORIGIN      
        1 aaacgagaaa taaaatatac tgctatacta aaaaaattct tagaaaatat caaaaaggca
       61 taacatctgg aaaattaaca gcagataaat ttgcagataa tatattgtct caagatttta
      121 tcagtagtat acttaatgaa aaaatagtca atgagacaaa ctttaagata tcttatagaa
      181 actatataga aactttaata aatattcaaa atgaaaattt atctaactta agaaaaaaat
      241 ctactaaaac tgcaaaatgt ttcaatatct ctcaaataac ccaattaaaa aacttactaa
      301 gtaatactgg ttataattta ttaattccat ataaatactt aactgctaga gatatagaag
      361 gaatagttac tcttattaat actgggtcta ttgaacttgg aaatgagaga atctacaatt
      421 atatatcaaa agtataataa tttaaaccta ttataaaaag gcaatttatt taataaaaaa
      481 tatttttaat attaaataaa ttgccttttt aattttggat taaatactgc tatccaagtg
      541 ctttttctag tttagataaa tgttgtattg gataatattt tagtagctct ttaaattgtt
      601 ctactgataa accttctgtt gttgtatata ttcttatttt ttcatctaag tcactattaa
      661 taaatttgtt ttttaaatcc tcaaaattta cactactcat tttacatcac tccttatgta
      721 acatattcat ttgtattatt ttatccaaat acataaaatt tattacataa aaatatatct
      781 atttaataat ttaataaaaa aaagctatct caatttagaa attactttct atatttgaga
      841 tagctctagc taaactaata gccaatagtt ataaataatt atttataact atctgttgct
      901 ttttccagcc atttgttgtt cagccatttc aactaatttt ttagtcatgt atccacctac
      961 ataaccattt tctcttgcag taaggtttcc tttatcaact tgttgataat tactcatacc
     1021 aagttcatta gctatttcta atttcatttg gtttaaagcc tcttttgctc ctggtactac
     1081 tgttctgttg ttgttattgt tacttgccat gttgattacc ttccttctgt ttaatttatt
     1141 ttgtgttgct gataatatta tgtgatttta aacattttta attcaggtaa tttttagcaa
     1201 ttaaaacctg ccaaatatcc agtagaaaaa gctatttgca aattgaatcc acctgtatat
     1261 gcatctatat ctattacttc tccagcaaaa aataaacctt ctactaattt tgattccatt
     1321 gtacttgaat ttatttcgtt tacttttaca ccaccagaag ttattatagc ttcttcaata
     1381 ggtctgtatc tctttactgt aaactttaaa ttttttaata aatggactaa gttttttctc
     1441 tgctctctag aaatttggtg aacaaccgta tttggattaa tttcacttaa gtttattatt
     1501 ataggtatta gtttttttgg aagtaaatca tctaatgctt tttcaaattt tttatttgta
     1561 tacttctgaa aatctttttg aactctttta tccaattttt cctcatctaa tgcaggtttt
     1621 aaatctaata atatagtgta attttctttc cttgtatctt tcattctaca acttgcagac
     1681 ttgattatag gtccatctaa accaaattta gtaaattcaa gttctccaaa atcactataa
     1741 actttctttt gtttgctatt aaacaccctt atttcaacat ttctcaatga taatttttct
     1801 aaatcttttg taaaactttc ttgtacttct ataccaatta aagatggttt tgtatctata
     1861 attgtgtgcc cctgtgaaat tgcaaattta tatccatcac cagtagaacc agtaagtgga
     1921 taacttaatc caccagttgc tactacaact gaatcacact taatttcttt tttatcgttt
     1981 aaaattactt tttcaatttt attattttta gatattattt tttctacttt cgaatttaat
     2041 aatatattta ctttcttact tttaagttgt ctttcaagag catttacaat atcaaatgct
     2101 ttatcactct ctggaaaaac cctttttcct ctttctgttt tagtctttac tccaagatta
     2161 ttaaacatac ttattacatc atcatttgta aaagtataaa aagcactata aagaaatttt
     2221 ccatttgtag gtacattttc tattaattcc tctatttcac aagcgttagt aatattacat
     2281 ctaccttttc ctgttattgc aagttttttt cctaatttat gatttttctc aattaatgtt
     2341 acatcatagc ctttctcaca tgcagttgat gcggctatca tccctgctgg tccaccacct
     2401 attattacta ccttcttcaa ataatcactc ttttctaccc ttaatttttt taatttaaac
     2461 tattgactct ataccttaaa atcaatttaa ttttaaaagt ttaaataatg ctggagctcc
     2521 tgctattcca taaaaaacaa ctactgtatt cttaataaaa ttcataaaaa ttatactcat
     2581 agtagagtca cttatattta aagtgactat taacattgaa ataaacaact taatgccaat
     2641 atataacatt cctattgtta ctatcccaac caaaaaccta catattcttg aaaaaattat
     2701 atttttactc cccttatttt tattgctaaa atttattttt ttgttattat tatctgtatt
     2761 aaatttaaca aatctatcct caaccatata tccaaataca aatcctacta ttataccaaa
     2821 tttttcaaaa tattcagggc tatttagaaa tatagccact attataaatg gtataagtaa
     2881 aactacaagt aaaatataat ttttattatc atcaatatag tcaaatattt ttacaaatac
     2941 aactgtaaaa aatattccta atatccaacc cgctatcaca tctattggcc aatgaacagc
     3001 taaatacagc ctagacaatc ctactcctaa aaccataact gcacctatta aatgaagata
     3061 tctcttttta aatatagtca taatactaac ccaaaatgtt gttgcagttt gagtatgagc
     3121 acttggaaaa gaataaccac cagcagtaga aactctcaat gattcaagac cttttattcc
     3181 tattggtctg ggagctttta caaactcttt gatgcctaaa tttacaacaa aatttccaat
     3241 tatagcaaac agtattttct gtccacattt tttatttata caccagtata taattgttgt
     3301 aattaatatt aataacggtg cttctgtgct tattgtaaag acaagaaata taaagttcaa
     3361 aattggattt cttaaatttt ggaaaaataa taatatattt aactgaatat ccatatagat
     3421 gtctccttta ctaaaatttt atataattaa ctaaaaagca ctaactccct tagaaattag
     3481 tgcttttgat tcacatttaa atctattcta catcctcaac tatacctata taaggtaaat
     3541 ttctatactt ttcagcatag tctattccat aaccaacaat aaatttgtct tctataacaa
     3601 atccaacata gtctacaggt atattagctt ttcttctctg aggtttatca agtagagtac
     3661 atagttttaa agattttgga tttctagttt ttaaagctgc aactagatta cttaatgtta
     3721 aaccagaatc tattatatcc tctacaatca acacattctt tccttcaata tctacatcta
     3781 aatcttttaa tattttaact gttccagaag actctgttga gtttccataa cttgtaacac
     3841 tcataaaatc tatatttaca tccaaatcta tacatcttat taaatctgaa acaaatacac
     3901 tagctccttt aagtatacct accactagta aatcttcgcc tttaaagtct tcttctatct
     3961 tttttcctaa ttcataaact ttttctttta tttgttcttc tgtcaacatt tttcctgtaa
     4021 ctttgtacat tttgtatcct cccgctttcc ttctattaac ttatatatta tagcatacca
     4081 aaatatcaat taaaatcttt ttcatcattt ttaaacctaa attaacagct tatccatact
     4141 tttttgcttt ttacattaaa aatttggaat aacgattcct ttgtattata atctatatgt
     4201 acatatatta atcagttatt tttatcgatt atataatttt atttttggag gtacttttat
     4261 gagcacaaac catggagcta atttatatag tttatctagt aagtatggct tttcaaagga
     4321 agaatttatg gattttagct caaatataaa tccttttggt acatcaagtt tagccaaaca
     4381 atacattgta aacaatatag atatggtatc tatgtatcct gaccctgatt acatagactt
     4441 aaaaacttct atatccaatt actgcaaatg ttctatagat aatatagtac ttggcagtgg
     4501 agctacagaa ctaatttcat catttataca tacaattaac cctaaacagg ctcttttact
     4561 ctctccagcc tattcagagt atgaaaaaga gttatctaaa attaattgtt ctatagaaaa
     4621 atactttgca aaagaagaag ataattttca tataaattta gaaaatctta taaaaactat
     4681 caatgctaaa gattatgatt tggtagtaat ctgtaatcct agtaatccaa ctggatttgc
     4741 atttactaaa gtagaagtga gagaaatttt aaaaaataca gactcatttt taatgattga
     4801 tgagacttat gtagagttta ctgatacaga tacatactct tgtactcaat tagttgatga
     4861 ttattctaat ttattcgtta taagaggtac atcaaaattt ttttcaacgc ctggaataag
     4921 gcttggatat ggtcttatat ctaacactaa tgtcaaaaat gaaataaata aaaatctaga
     4981 tttatggaat ataaacataa tagcttctaa aatgggtgaa atcatgttta gtgatttaga
     5041 ttttatatca aatactattt ccttaatgaa cactgaaaga gattacctgc ttaaagagct
     5101 taagaatata aaaagcttag atgtatacaa tactaaaggt aatttcatat tgtgtaaaat
     5161 caagacaaag gaattgactg ctaaatctct tcgagagcaa ctgctcccac aaaaaataat
     5221 aataagagat tgttgttcat ttgaaggtct agatgagtat ttctttagag tatgtatatt
     5281 aaaacctaat gaaaataaat tattaatatc atctcttaaa gcaattttta aataaaaaaa
     5341 tcactttatt ttataatttt ttataccata aaaaatgagc tatctctatt tgagataact
     5401 catttttgat tattaaaaaa ctaagcactt tgctcttctt tgtttccttt tttactcatt
     5461 ccatcattta ttttatctac tactactgct attgcattat ctcctgatac attacatgct
     5521 gtaccaaaac tgtcttgagt taagtataaa gctatcatta aacttgcaag cccaccatct
     5581 gatggtattc caaccattgg taggaaagga agtgcactca ttatagcccc acctggtgct
     5641 cctggtgctg caaccattgc tatacctaac attgcaatat aagggaataa tacacctatt
     5701 ccatgtggca taccattcat cattaaaact gcagttgtaa atcctgttat tgatatcata
     5761 ctacctgata aatgtattgt tgcacaaaga ggtacaacaa attctcttat ttgcttactt
     5821 actccatttt tttctgcaca accaacatta actggtatag ttgctgctga agattgagtt
     5881 cctatagctg ttaaatatcc aggtacttga ttttttaaca ttcttactgg attttttcct
     5941 gaaaatacac ctgctgctgt gaattgacat gccatatata caaaatgtaa aggtattact
     6001 actaagtata ctttccagaa tacccctaat attgtccata cttcccctgc tatagttata
     6061 tttgcaaaag ttcctgctat gtataaaggt aataaaggta taatcactgt tgacaacgtt
     6121 ttcgttacga ttccttgaaa ttcttggaag aaattaaata aagtctctcc ttttccatga
     6181 tttcttaaag ctgatattcc aagtcccatt acaaatgcaa atacgattgc agctgttaca
     6241 tctaccatag gctctaatgg aattgtgaat attggagcta acattcctgc ctctgggtct
     6301 ccaatttgac ttgcaacact tgcatcaata aaatttggga agattaatgt agatactgca
     6361 aatgataata atcctgctat taaggtagaa ccatatgcta ttcccgtagt tatccccaat
     6421 aactttcctg cacctgttgc taaatcagct atacctgctg ttacaaaacc tataattata
     6481 aatggtataa caaattttag gaatgctgag aataaagtac taactgttac taatatttgt
     6541 actattattt ctggtgcata acttccgatt aaaataccga ctatgatacc gatgattagt
     6601 ttgggcacta aacctatttt tttcttcata atatttaccc tccataactt ttttaaatta
     6661 agcattcttg cacattgaat acttagttaa atattggata tccacttatt atgataatag
     6721 agttttacct ctccgtcaac aatttaacca ttttttgtta ataaaaaaaa gaataacata
     6781 tataaattgt tattcttctt catcttttat agaaaattct acattttcaa ttatatttga
     6841 atgtttatct ttttttgcga taactctata cttattaatt tcttcattca ctatacctat
     6901 actccaaatt aaaactatag catcatctat aaaaccaaat gcccctgcaa tcatctctgg
     6961 aattatatca accccagata caaagtagga tatagtaaaa attaatacag aaattacctt
     7021 tattttatca actatattga ttcttttatc tgtcataaaa tcaggtagtt taagtaaatc
     7081 aaatacaaaa accaaaccaa atttagcatt tttaaatctg accaaaattt tttttaaaat
     7141 atctaaaact atattaatga ttatttttaa aaactccata tttatcacct cttataatta
     7201 taggttattc tacattataa ccgatataat taatttgatg aacatattag atataaattt
     7261 tatcaattag tttatattta aattataata attcaattcc tgcactacta caattttgaa
     7321 tcatatcctg tggccatact ccaacttgta cttctcctat atgagctttt tgtaagaaat
     7381 acatacatat tcttgactga ccaattcctc caccaattgt atatggaagt tcgccattta
     7441 aaagcatctt atgatagtca aactcttttc tctcttcaca tccagcaagt ttcaattgtc
     7501 tatcaagaga ttcttcatca actctaattc ccattgaaga taattctaat gctgaatcta
     7561 aaacaggatt gtaaaataat atatccccat tcaattccca atcatcataa tcaggacttc
     7621 ttccatcatg tttttctcct gatattaatg tttttcctat ttgagttata aatactgctt
     7681 tcttctcttt tacaatttta tcttctcttt cctttggtga taattctgga tacatatctt
     7741 ctaactcttg tgatgttata aaagttattt cttctggtaa tatttctttt ataccttcat
     7801 acatactaca tacaaaaatt tcagtatctt taaatactcc atacaatctt tttacaacat
     7861 cttttagagt cttttcattt ctactacttt tatctataac caattcccaa tcccattggt
     7921 ctacataaag agaatgtata ttgtctaatt cttcattttt tcttattgca ttcatatctg
     7981 tatataaacc actaccaact tcaaacccat attttttaag ggctaatctt ttccattttg
     8041 caagtgattg aacaatttct gcatttttat tcataaatgg tatatcaaag cttacagcct
     8101 tttctccatt taaattatca tttgcacctg tttctggcaa tacaaataac ggagaagaaa
     8161 ctcttataag atttaattca ttacttagtc tcatttcaaa aaaatctttt aattttttta
     8221 tagctatttg tgtatcaatt acgttcaaac tacttttata atcctttggt attattgtgc
     8281 tcatatcatt cactccctat atttatatat ttttccatta aaaaaaccct tcatccctat
     8341 ataaaaggga cgaaaggttg cttttccgcg gtaccaccct gattagtttg aaataaattc
     8401 aaacccagct cacaatgtac agatattact cgatacaccc caatatgata acggtttggt
     8461 tccgactaag cctactcttt taaaatttcg gttagcaact ccaggatgtt cttcattata
     8521 gacttcatat tggtctcaca ccatcaccaa ctcgctttaa ttacattcta taactactct
     8581 tcctttcaaa gtctttaaga gtttaattca ataaaattta gctctcttat gttttctatt
     8641 tattcataat agtatgataa gtgattagtt aaaatttgtc aagtttatta tttttttatt
     8701 tttaaacact ttataaattt ttacctatac tttataaatt ttcaaatata gtctttaatc
     8761 tgtccataca ttcttttaat aaagactgtg gacaagctac atttattctt tcaaatccta
     8821 ttccttcttt tccaaatata taaccttcat caaataatac attagctttt ttaaacatta
     8881 aatcctcaag ttctacttca tttaatccat aagcagtaaa atctaaccat gctagatatg
     8941 ttccttctgg ataaacaagt tttacttttg gtaggttttc ttttaagtat tcatcaataa
     9001 attgtatatt attatctaag taatcattta attcattaag ccagtcttca ctttcattat
     9061 atgctgctat tgtagctaca atagcaaagg gatttggtga agttgcaact ccaacagctg
     9121 taacctcttc ttgatatttc ttttttagtt catcattatt cgctattata ttagacaact
     9181 gcattcctgc cagattaaat gttttacttg gagctataca tgtaactatt ttatccttgt
     9241 actctgggca taatgactgt aaaggagtat gtttaaatcc ttttctaatt aaatcagaat
     9301 gtatctcatc agctattatc cataggtcat attttttaca tatttctaca acctttttta
     9361 attcatcttc tctccaaacc cttccaacag ggttgtgagg actacaaagt atcagtactt
     9421 tattgttgct acacttagct ttttcttcta aatcatcata atccatccta taagtaccat
     9481 tctcatatat tagaggattg tttacaacgt ccctattatt gctctttatc ttagcttcaa
     9541 atgggtaata cactggtttt tggactatta caccttcatt agaattagtt aatattctta
     9601 ctaaaatagc aacagcaggt acaacaccag gactaaaaat aatatctttt ctatttattt
     9661 cccagttaaa tctcctttta taccaatcac aaactgcatt aaagtattta tcactatcat
     9721 ttgaactata tccaaatatt ttatgttcaa cttttttacg taatgcttct attattggtt
     9781 ctgcacattc aaaatccata tcagcaatcc aaaaaggcaa accatctttt tgtgcttttg
     9841 ttgaacaatt agttctaaaa tcccatttta cacaatctgt tcctactcta tctattactc
     9901 tgtcaaaatt atacttactc attttttccc tcctaagaat aaaattttta taattgttaa
     9961 gtctattact agatgcactt tggtattatt ttacaattct taatattata ataatatcac
    10021 ttttttgtcc aatagattta aaatataatt acttttccat catatttttt caatattcca
    10081 aaatcagttt cattatatca aaataagatt gctcatatta attattttct aattaacata
    10141 agcaatcttt ttctataact tctataatta taattttaaa tgtagaatta ttagtttgga
    10201 tgttatccca atctcttttc aaccaatcta caccatatat ctacaccata ttctaaagct
    10261 ttcgtatcaa atgttacatt tggattatga aatcctggtg tagcatcagc tcctaatcca
    10321 atatatgtag ttttacattt tagtttttgt gtataataat ggaagtcttc tccaccagaa
    10381 tttttaaata tacctataga tgcatcagct cccaatacat cttttatagt ttcttcagcc
    10441 aagtttacaa gttcttcatc aaattctgct gctggtactc catctttgga aattagtaca
    10501 gcttctgcat ttatagaact tacaacagtt tttacagcat gtattgcttt ttcttttaat
    10561 tcttctatta tatcattact ttctgccctt atatctaaag ccataaatgc ttcatctggt
    10621 atattattat aagtttctcc cttaactgat atatttgtta cttttataga atttggtata
    10681 gctggattta ctcttattgc atttattgca ttcactgcta aacagacagc atctactgca
    10741 tttactccta aatgtggttt agaaccatga caagtgatac ctttaatcgt aaattccatt
    10801 atacagctag cacaatggta cattgcaggt atcgcctttc ccaacctaca atcttgtcca
    10861 ggtcttaaat gcatccctac catttcttct acatcatcca acaaaccaga atcaattact
    10921 cttaatgctc catataattt ttcttcacct ggttgaaaaa gtatttttaa cttacctctt
    10981 tttactaaat ttctctcttt tattaacttt gcagctgtta aaagcataga agtatgacca
    11041 tcatgaccac aagcatgtat cattttcttt tctccatcta tgataaattc caatgcatcc
    11101 atatctgctc ttatagcaaa tactggtcct tcttttttag aatctatagt tactataata
    11161 ccagttcctg caactccttt attaatattt tcaaacccca ttttttcaag ctcttttaaa
    11221 acaaactctg atgtcttata ttcttcaaat cctttttctg gtatagtgtg tagataatca
    11281 tacactttat gtacatactc aatataatct ttgttagttc ccataatcta gctcctcctt
    11341 aaaatttaaa ctttccattt atattaaatt tttattataa ttacctatac tacgaaataa
    11401 ttcattataa gcattgcaat acaaccattt aaagttgcta taacaaacat atgtggataa
    11461 tatttagttt ttaactcagc tgttcctaaa agtctcccca taaattgtat ctgcgctcct
    11521 gaaagcaata acattggcaa tagaattgca acatgtgctt gacttatttg acctgctgta
    11581 aataaacctg cgattactcc agatgctcct cccattgata taaatattgt cattatagct
    11641 gttgctgcaa cacctggaag tccaaagata ctcattacag gtgtaaatat tgtccctatt
    11701 acatccaaaa gacctgttaa gttgaacaca gaaattatag caaaaccgaa gatgacattt
    11761 ggagccattg aatttgtact tatttggaat ccatttctag ctcctccaat aaacgcatct
    11821 atcacatttc cttttttaac ttttacttct ttttttgcta cctcactcat gttaagcttc
    11881 ccccttgtca aatttattta aatataatct aagtaagttc gccccaacaa acttcataat
    11941 taatattaaa gcaagtggta taaatattgg tacatctcct ataaatggaa atagtgctgc
    12001 tccagaagca aagaaattcg taattgcaga cgcacctgaa aattgaaatg cacaaaatac
    12061 agctttttgt ttttcatcta tatacccatc atctttaagt tctttagtca tagatgcagc
    12121 tgcatctgta gactgtaaac tagctatcaa agttagtcct gcaaatccag gtaaccctaa
    12181 taatggcttt aatagtggac taagaagctt ttgagctgcc ttcattccat ctaagtggtc
    12241 tataactcta actactccaa gtgcaaacat aactgatggt attaatgtca atgcatatag
    12301 ccatccatct cgagggccag tacctccatc acctctaaag tttgcagcta atgtacctac
    12361 accatcatta attgttccca atgttccaaa agaacctaat acattgttaa aatccaatac
    12421 ttttaatggt cctggtgcat ctttaaatat tcctgaaaaa aataatgctc ccaatattaa
    12481 tgctacatac ccataccatt ttacctcaac tttttctgtt gttgattcta atttactcat
    12541 ataaattctc cctcctgttt aaatgaattt tattagtata cttgtttaat aagcaaaact
    12601 tatgccaata ccttaatgat aaagcctttg tatttatttt tttattgtaa atttattcca
    12661 gtgattaaat agcttataat tacttacttt tcaagtttaa aaatataata tttttttatt
    12721 aattatttaa aatatacatt acaatataaa aagctatttt ccttatcttg caaaaataat
    12781 ttcaaaatag gtttttatag gataaaatcc taaaaaaacc tattatttaa tcaaatatat
    12841 aaatttatac tactatttgt tgtataatat aacttgcctt atactttaaa tactttaaaa
    12901 ataaatacta ttttgttagg agaaataaaa tggataaaaa gaagttaatc cttataacat
    12961 atgataaatt gaatagtgac cactacaaag aagaattaac aaactttttt ggagacgaaa
    13021 taatcataga aacacaaaat atacttgatg gaataaaaga aaatttagag ggagatgtag
    13081 tgctttctct atcaccttta actagtaatt ttttaataaa acattttaag gaagatattg
    13141 aaattattca tggaacgaaa gcactttcaa aacttggata tgaaaaaatg atgaaactgc
    13201 ctccaggtac aaaattgtta cttatgacaa ccaataaaac ttcagcattt gagatggcta
    13261 cttatctata taaaattggt ataaatcata tagattttgt accgacatat ccagattgtg
    13321 atgaaatata tgatttagat acagctataa caccaggtca gattagattt ataccaaaat
    13381 acataaaaaa tattgttgat ttaggttgga gaaaaatctc attagataca tatatgtcat
    13441 tattagtagt attaaaacta aaaaatgaga aatttataga aaaattatac aaattgtcca
    13501 aggagacact aagtcatgat ttcttaaata catcattaga taatatatct aaattaaaaa
    13561 ctatacttta catgaccatt gatgaaatag gtgatggtct aatatttttc aataccttta
    13621 ataaggttac ttttgtaaat aagtctttac ttaatatgtt ggaactagat gaaaaactta
    13681 taaaatcacc ttccttaatg gaatatatgc caaagagttt cttagataaa attacaaaga
    13741 acttaaatat agataatatg attatataca tagacgaaat agataaaaaa ttcatacttt
    13801 ctaaaaaacc attttatctt tataaaaata tagagggttg cttaattaca ttaaaagatg
    13861 taaacaatat agaaatatta gaacaaaaaa taagaagtga ttctgtcaaa agaggttatg
    13921 tagctaaata taaatttaat aatattattg gaaatagttc tattataaaa gattgtatta
    13981 aaaaggcaaa aaaaatggct cttacagata atcctatatt aataacaggt gaaacaggaa
    14041 caggtaaaga agcctttact cagtcaatac acaatcattc aaatagaaaa aataaacctt
    14101 ttgtagcaat aaattgtgct tcattaccaa gtgaattact tgaaagtgaa ctatttggat
    14161 atgaagatgg ttcttttact ggagcaaaaa aaggtggaaa aaaaggatta ttcgaattag
    14221 ctcatactgg cactatattt ttagatgaga taggagatat gccacatgat ttacaggtta
    14281 aacttttaag agtcttacaa gaaaaagaaa ttagaaaaat tggtggtaca agtattattc
    14341 caattgatgt gagaatatta gctgccacaa ataaagattt agagaaatta attatagaaa
    14401 ataaatttag gatggattta ttttatagga taagtatgtt cactttagat ttacctcctc
    14461 ttagaaagag attagaagat atacctcttc ttttagaatc atttttaaaa gaacttccct
    14521 ataaaaacat aaaactcgat aagagtcttt tagaagcttt aaattcatac acttggatgg
    14581 ggaatattag agaactgaga aattgtgttg aatatatggc ttacatgggt tccaattatc
    14641 ttacaataaa tgatttacct caaaacatat cttcaaaatt aaataataat catatgtcaa
    14701 gtaatatgtc catattcaat gatttaaacc aatatgacaa aaacatatgc atttctatcc
    14761 taaaatcatt gcacatgaaa ccaatgggga ggacaaagtt aatgaaattt atggaatata
    14821 atgtcacaga atacgaagta agaaatatgc tagaatattt gacacgcaat ggatacttaa
    14881 tttctagtaa gggaagaaaa ggctcatcaa taactgagaa aggcataaaa ataatagaaa
    14941 ataatataat ttaaacctat agtaattcat ctttacttta tcaaaattta tatataatta
    15001 taatttttta tttttctata aattttttat aaaataataa aacttattta tattaaaaac
    15061 gaagctatct caacatatgg ataagcttct ttttaattgt taaaaagata aaaatatatt
    15121 tgatttaaca gaaaaagagt gcctcataaa ctaaaaagtt cattttgaga cacgtcctta
    15181 atattaataa attaattggc ttaaaattac tgattgataa ttataaagta cctctgttaa
    15241 aggagtaaat tctgaaccga ttccaaatct taattctgta aacgcctcta aataatctgg
    15301 gtcacataca tcttcttgtg ttaaatcttg tttcaccatt tcagtagcaa gataaattgc
    15361 tactgatggt agaaaagcat ccattggcat aggatatcca ccaagtctat ttgacatgcc
    15421 aaaagcctta gccttttcac ttatcatgtc gtttatttta tcataatttt gagcatcttt
    15481 ttcagatatt tttagaccca taacactagg atatgtttgt attggtgatg gattgctttg
    15541 ctctgcaact atatacttta attctaaagc cttagtcaat ataacttcat ccatatactc
    15601 atttacacca aatacattta tatcttttcc atatttttta acttgttttt caatatcttc
    15661 atttaaaaac tgcttaactt tgtttttgtc ttcttcagta tttatatttg gagtattaac
    15721 ttgtacaaat ggcaatccta tatttttgca agtctcttta atcatttcta atcttttggc
    15781 tatattaaca tctttcaaat catctgtaga ggcataatga ataaaagctt ttgctcccat
    15841 ttcttttgaa cgttcagcta atacttttcc tctttcctct gcactaaccc ctagattcac
    15901 atcaacaaat tggcttaatt ggtttttatc atctcccata ggggcagaaa tagttattat
    15961 ttctggacgc ttttccttta ccttttgtaa agcaggtaaa agccctgctt ggtcagttga
    16021 aactacaata gcctgaactt ctttatcgtc agccaacttt actatcttat taatagcact
    16081 gtctatatta gaagtaaaat tctctggcaa tacaacatgc tttatagttt gtttaacttt
    16141 agtttgacca tctttgtctt tatcaatttt attctcttcc tcatattctt ttgccatctc
    16201 ttccaccata ttgtattgta ctttattttc agataatggt tgagttacca ctgcaacttt
    16261 aaaatcatct ataattttct ctttatcttt cttgcctaca agtaaactac aacctgtaag
    16321 tccaataatt aaacatatgg atagcataaa tgctgttatt tttctaagca ttaattaaaa
    16381 cctcctaaat ttgtacattc ttatcactat tactaatttt atcatacttc aaagaaaaat
    16441 tatattataa aaaattatat acatgctatt ataatccaat ctaaaaagta ctatgggtag
    16501 attaggttta gattaaacct acccatagta ctaaaaatta atatattata aaattaaatt
    16561 aattacaaat tattatgcta cttgtttgtt gctttttata aagttaccaa ctattccacc
    16621 caatatagct ggtattaccc agttaaagcc caaacctgca agtggcaagc tttgtataaa
    16681 tggaacagct cctgtcattc catttatagc tgataataaa ctaatcacta atgtaacata
    16741 tgctgcacct ttaaaagcat tatcattctt tatatgttta ccagccaact ccataacaac
    16801 tattgctaat aaaacaggat atatagtttg taggattgga actgatatgg ctattataga
    16861 atcaacacct aaatttgata taagcatact agctacacat atacctataa ccagttgttt
    16921 ataactcgcc ttacttattc cttcaaaata agttgatatt gatgctgtta aacctgtaga
    16981 agtagtcaga caggcaagtg ccacaattac acctaaaatt acctttccta cttgaccata
    17041 taacaatata ctagttattt caactaataa agatgcttga ggtatactag tatcatataa
    17101 agttgaaact gttgcaccta aataagtaag accaccatat actactgcta gaaatacaca
    17161 ggctacaaaa ccagctttaa tagtcattcc tatttggtct ttatctgatg tatatccttt
    17221 agctattata gacatcaaca ttatagttgc catagatgct gcacctagag cgtccattgt
    17281 ttgataacct tgtgatatac cttcaccaaa tagattttta tctatcatat gctcaggact
    17341 catagggcct gctggagaaa ttataccctt tactattaaa acaaataata ctaataataa
    17401 cgctggagtt aaatacttac ctattatgtc tataacctta gaagacctaa tagtaaatgc
    17461 taaagttagc ccaaagaaga ttattgaaaa tacagcttta gctactggac catggtctcc
    17521 aaatataggc ataataccca tttcatatgt tgttgcgcaa gttcttggta ttacaagaag
    17581 tgctaaacat gctagagcag ctacactcat tactcttgct aaccctttac cagctctcct
    17641 aagtacatca tccatgcttc ccttacatct tgctgttgct ataataacaa gcattgctat
    17701 accagcatct gcaacaacaa atccaataag aggaattaac cagtctttgc cggattccat
    17761 ccctaaaaat ggaggaaaca taagatttcc tgcaccaaag aacatagaaa ataaagcaaa
    17821 accaactata aaaatatctc tcatctgctt actcacacta aattaccccc tttgaaaata
    17881 ttttgaatat taagataatc ttactttatt ttcagaaaaa tgtcaatctg gtaaaaattc
    17941 acacattgtt aacgttttcc caatttattt tatgaatatt tttttcattt tatgataatt
    18001 cccatcaatt tcgttaaatc aattgcttgt gacacatcaa aaattgctcc tctaatatca
    18061 tctataccaa tctcaattcc ctcaatatta ttagtagtaa aatctatgcc agaaagttta
    18121 gttccattaa agtttgcttt ttttaaattt gtatactcaa atactagatt gtcacctttt
    18181 acttcttgaa atacagaatt ttcaaaattt gaatctaaga tagaaactat cttaaattta
    18241 gagaatgaaa agttagaata cttacctaaa acatccttga acaaaacgtt tttaagtata
    18301 caatcatcaa atctaactcc tatcaattta ctatttttaa attcaactct gtatatactt
    18361 cctccatcaa aaaatgtatt tgataaattg cagttttcaa ataccacatc aagtaaatca
    18421 atctttttta aattacaatt ttcaaaagac acatttctaa atatacaaga ttcaaagcta
    18481 actcttacag aatctaaatc acttataact tcattttcta taattttatt aaatattttt
    18541 tcatcattaa atatatcttc aagtatatct tcaagatttt caataatttc taattctcct
    18601 gtaaatttag gtttttgcac tttaataatt ttagtcattt tcccctccac tataaattat
    18661 attatttttg atattatttt ttttaatata ttaacttaat atacatattt gatatattaa
    18721 aaagttttta cgaaatatcc atgtattcag tacttttata attatatcac aaactcattt
    18781 ataataaact tccattaata gtataaaaca agttagaata attgacatta tactcataca
    18841 tattcaatta ttggaaaaag taattttttt caataaataa ccttaatttt ttataaaatc
    18901 gacaaaaaaa cgaataattt tattatattt attgtaaata atacaatatt acgatataat
    18961 acaacagaaa aacaaataga aaatgttcat ataatattag taatacggtc taatagtttc
    19021 tacaaactca ccttaaatgg gttttctatg aatagaatgt caactctgaa tatatgttct
    19081 attctatcta tatgaatata tatttttttg tttatatctt aaagtttttt ggaggtaaaa
    19141 atggtaccaa acactaacaa tgtacaacca ggtggaaata attcatcatt aagcttttta
    19201 gacaaaatgt ttaaatttag cgaacgtggc tctagcctta aaacagaagt aataggtgga
    19261 gttactacat tcttaacaat ggcatacata gttttcgtaa atccagcaat attatctgaa
    19321 gctggaatgg ataaagccgc ccttataaca gttaccatac tagctacagc cattggtaca
    19381 cttatatttg cgattttagg aaatgcacca tttgctctag ctcctggtat gggattaaat
    19441 gcatttttca catactcttt ggttataggt gcaggaatcc catggcaaac aggtcttggg
    19501 gtagtttttc tatctggatg tgtcttcttt acactcgcag taacaggtct tcgaaagaca
    19561 attgcagacg caattcctag agaattggca gtagcatctt cagcaggtat aggtcttttc
    19621 cttgcttttg ttggtttaaa aaatatgggt gttataatag ctaatccaga tactatagtt
    19681 tcacttgcag attttacacc aacagtttta atagcccttt ttgctcttat cttaatggca
    19741 atactagaat ataaaaaagt taaaggtgga atattgataa gtatagtagt tgcaacaata
    19801 atatctgtta tatttggatt tgtggagttg ccaacagcaa taatctcaac acctcctagt
    19861 atagcaccag ttgcttttaa attagatatt gtaggtgcat tgaaattctc attaattgga
    19921 cctatattct ctttcatgtt tatagacatg tttgattcat tagcatttct tattacttgt
    19981 tgtaaacaaa tgggtcttga agatgagaat ggtgaaataa aagatttagg aagaatgtta
    20041 tatgcagatg tttcttctac tttaataggc tcattcttag gaactagtac tgttacaaca
    20101 tttggagaat ctgcttctgg tattgcagca ggtgcaagaa caggacttgc ttcaatagta
    20161 acagcagcat tattcttagc tacacttata tttacaccat tacttggtat agttcctact
    20221 tacgctgcag ctcctgcact tgtaatggtt ggtgtgttta tgtttgaaag cataaaacag
    20281 attgattttg ctgatagcaa aatagctgta cctgcttttg ttacagtttt attgatgcct
    20341 ttaacttata gtataagtat tggtttatgc tttggattta tttcatatat aataatgcat
    20401 gtagtagcta aagaaactga taaaatcagt attacacttt ggattatagg tttacttgca
    20461 gttgtaaact tagttctaag ttaatatttt taaatagttc taggtcaata ttttaaatta
    20521 tatagaataa aatcttattt attttaaatt tataaatagc aaaatcactt tatatgtaaa
    20581 ttgattttgc tattaacttt gtatagaaaa tttattatca taatatatag atataaaaat
    20641 atatagaaaa ggagtggtgt ttatgtcaca attacttata aaaaatgcat atctaattac
    20701 tatgaatgca gatagagagg tatatgaaaa tggaagcata cttattgaaa ataatattat
    20761 aaaagaggtt ggtaagtttg atattaatat tgtagataaa gatgcagaga tatatgatgc
    20821 taaaggaaaa atactaatgc cagggctagt caatactcat gttcacttat ctcaacaatt
    20881 aggacgtggt cttgcagatg atgttgtact tttaacttgg cttagagaaa gaatttggcc
    20941 atacgaaagt agcttcaatt atgaagattc cttgatttca tctactgcat gttgtgttga
    21001 attgataaaa tctggtgtca ctacattttt agaatctggt ggtcaatatg tagatgctat
    21061 ggttgaagct gttgataaaa ctggacttag agcctgttta gctaaatcag ttatggatac
    21121 aggagatggt cttcctgagg catggcaaaa aactactgat gaggaaatca acactcaatt
    21181 agacttattc cataagttta ataatacatc taatgagaga attaaaatat ggtttgcatt
    21241 aagaactatt tttaatacaa ctgaagaatt acttgttaga actaaagaac tagctgataa
    21301 atacaataca ggtatacata tgcatattgc tgaaatagct gatgaaattt catttgtaaa
    21361 gcaaaacaat ggagttggaa cagttgaata ccttgataaa ctaggtgtat taggaccaaa
    21421 tcttttagct gctcatacag tttggcttac tcataaggaa attgatttat ttagattaca
    21481 tgatgtaaaa gtttctcatg acccaggttc agctatgaaa gtggttctag ggtttgcatc
    21541 aattcctgaa atgttagaaa aaggaatacc tgtttcaatt ggtactgatg gagctccttc
    21601 aaataataga atggacctta tgagggacat gtatcttaca tcactaatac ataaaggaag
    21661 aactttaaac ccaactgtcg taccagctga agaagtctta gaaatggcta ctataaatgg
    21721 agcaaaatgt gctttactag aaaaagaaat tggtagtctt gaagtaggaa aaaaagctga
    21781 tatgattatt ctaaatccag atacaattca ttgtttacca atgcataatc caattggaaa
    21841 tatagtttat tctatgacta gtgaaaatgt agactctact atttgtgatg gtaaatggtt
    21901 gatgaaggaa agaaaagtat tagttgtaga tgaatctgaa ttattaaata aagttaaaaa
    21961 acaagcttct aaaataaaag ataaagcaga agttaaaatt ccatctaaat ttaaaattat
    22021 aaaataacat aaatttcaat tgttttgtaa atatgaatat ataaatatat ttatatacat
    22081 catatataca aaacaattgt ttttttattt tatattcatt agcattgctc ataaaataca
    22141 ccataattcc agaaaaaata accaatcagt taggattaca tcatctaagc aatatataaa
    22201 cgtcttagtt tataagtttt attctactct tatctaaaac catctttaaa gagttttcaa
    22261 ctgtttcaat tacatcttta taactcaagt acacatttgc gtagatacaa tcttcatata
    22321 aattatattc agttactcta caatacagca gttttcctcc atctaataaa ttgctcaaaa
    22381 tatagttttc ttttcttggg acatagccta tcacatatcc agtttcacca actattttaa
    22441 tagctttttc atcatataga ttatctttct ctctagttaa atagtatatc ttacttttct
    22501 ccaattcttt ttcaagatat tctctatttc taaaccttga accagcaaca gctattgaag
    22561 tcaaatagat atccttacca tgttcatcta cttttatttt ttcaatattt acaaattctt
    22621 tttttaaatt attactttca tataatactc ttcttaattc atccttcaat ataacatttt
    22681 tttctttttc atacgcttct ttaacaattt ttaattcttc aagagatagt ttctctctgt
    22741 atctttttaa gatatttatg gattcttttc ttacttcatt tatatttcca aatattcctt
    22801 ttaaagatat attctttcct tcaggatata gtgatttact tcctttaagc acaataaaaa
    22861 ataacatatc atcataatat tcttgagtca atttatcttt ttctatatct ttcatttttc
    22921 caattaaatc atctatttta aacgtctctt caaaaaaatt taataatttt aatctagaac
    22981 ttgtcgttcc ctttttagat atatgccaat atacctcaaa atctctaata tctctattta
    23041 gatatggcaa caagtcatca aaagataagt ttacatcata aatttctgac atttttataa
    23101 tatcttctgt ttttccacta gcatctctta atgcttcaaa atatatattt ttccattttt
    23161 cactgagcaa gataccattt atttcttttt caaattcaat cttattgcac tctatatttt
    23221 catcttttaa gacgtttata gctattagga aaattgaata taaactttca aagttagtcc
    23281 cataatttac tacagtaggt aaaaatcgat tcactaattc taatttatta cctatatatt
    23341 taaattctac acttagcaag taattgcata taagacgtgc taaattattt atcttttctt
    23401 tatctaaatc tcgtttttca agatattcat tcaaatctac aattgaaata atatagttca
    23461 tcaataatcg ttcgtacttt gtatccttat aaccatcttc aattagatag gaatttattt
    23521 tagaatctaa attttccata ttaacaatag caaatacttt tattgaacct gtagcctttt
    23581 tagataaatt aaataaatat gtattgtaaa attcaagttt tttaatagta ttactcagat
    23641 aaaatacgta ttctccagat ttagaaaatg tatctacaac ttctcttaag ttttctacat
    23701 ttagatattt ctcacttaaa actaacccta gttttacata ctcaactttt ttactcttat
    23761 atattaattc tttagttaat ttatataacc atttctcatc aataatcatt tcttttacca
    23821 aagtatttat ctttttcata aaaatttcga aataacaaat taaagactta gaattactac
    23881 cctccaataa ataaatttca ttagattcac ttttatacat atttaaaatt tcatctacta
    23941 gattatttgc aagctctact tgttctctta acggtatact ttcatatata cataggtaat
    24001 tcatttcaaa tgattctttg tatccatcat aaccattaaa ttcctgcaat cgcttaaaaa
    24061 cattctccac caaattatcc tcctttacat gatgtaattt atattgatta tactacttat
    24121 ttcatcaagt ttacatttat acgcaaaaaa atattactag aaattgaaat tctagtaata
    24181 tccttattat taattatgta aataccctat cttataactg taaataatat ccttattaat
    24241 tttaattact tttaataaaa atctatccta gatttagact tctctatgca tatattatac
    24301 taatattaga catcataatc atacactttt tctttttcat atctcatgtt tacaaacaat
    24361 gcaagtaaaa ttccaacaaa tgttattgcc acattaaaca atacaacata ttttggtcca
    24421 ttaactcccc ctgattttgt aataatacct gctatattta aaataacata gtttgctata
    24481 ctagatgcaa tcataactat agatgttatt tttcctttat tagttggaaa catttcattt
    24541 gcagttgacg ttgttaactg aagaacacct cctgctgctg aataacctat tacaaatccc
    24601 cctaacatac aaatagttgg agtttgaaca aaatatacaa ctaatagcat aagtaaagct
    24661 attataggat atataactaa tattcttatt ggtttaatat attttttaat aagtaaagaa
    24721 gttattaata ctgcacatat tactcccatt gagtaaaagg attgaatttt tgtagggtca
    24781 gccatcccat acaatttacc caattcctga ttacaattta accataatac aaatgtagat
    24841 gtacatgtaa atccaataca aacaagagct atacttgttg gtgtaaattt catcttctct
    24901 gatttaactg ttttgccttt gttatcaata acattattag ctggtggaaa tggtaacaca
    24961 gctatcaaaa aggcatctac tacaataaga atcgctgtta ctataaaaat aactttaaat
    25021 gatattgaat ttgctgcaac aaatccaatt ataaaaggaa gcaaaaattg tgctaaagct
    25081 attgtaaatt tagtaaacat atttgctatt gttcctaaac tagcaaatat ctccatacaa
    25141 gaaggagtta cacaggtatc taagaatgaa tttgctgccc ctccaattat tgcaaataca
    25201 tatgctatat aaaaatttgg tgaaaataca attccaacaa agaaaattgc atgtagaaag
    25261 tttcctataa gaccacttac ttttcttcca tacttatctg aaataggtcc tgcaaatgga
    25321 taagatataa gtctccctaa tcctagtgca gcaataacag ctaaaacaat acttacatcc
    25381 aatgttccat ctgataatgt tttagccccc cacattgatg aaaattctgg tttgtattgt
    25441 cctaaaattg aaattccaat accaagtaaa aaatatgaaa aatacaacgc tatggcagta
    25501 ggataatatt ttttattgtt cataattttt ctcccattct tgttaattta ttaacatttt
    25561 tgtgtacaat aaactcatcc ccataatgga tttaaagtat agtcagttaa agcttcaaat
    25621 ttaactggac tatgaggcaa aacccactat gacaatttgt aatttattat taaaaatatt
    25681 gaaatacgta tgttttttca ttgtttaaga tattactctt atctatttaa agcataattc
    25741 attaacttct tctacaggca tttctaatcc agtatataga ttaaaagctt ctgctccttg
    25801 gtataataac attcctaatc caccaatagc cttacatcca ttagcttcag catcttcaat
    25861 catttttgtt ttcttaggat tataaacgac atctgttact actaaatctt ttcttaaaac
    25921 actagtatct tttatatttg tttcattgtc ataaggcttc ataccaataa gagttgcatt
    25981 tgtcaatata tcacttgatt gtatctcctc ataaagtttg tttgtatctt ctaaatcata
    26041 tagattaaca acacattctg gtacatcttt ttttatattc tcaactgttt gctctgctct
    26101 tttataaaaa tcatccttag gattaaagat agatatttct cttgctccat ctaaagcaca
    26161 ttgtacttgt atagcagttg ctgcaccacc agcacccata attgtaatct ttttaccttt
    26221 aacttctacc ccattttctt ttaaattacg aacatagcct actccatctg ttatatgacc
    26281 aactaacttt ccattgtcat ttacaattgt attacatgct ccaattatac gagctgctgg
    26341 agaaagttca tccatatatt ctgtaacagc agatttacat ggcatagtaa cattggctcc
    26401 ttttatatta aaagttttta ttgctaaaag tgcctctttt accttatcta ctgtgatatc
    26461 aaaggctaaa tatctataat ctaaatctaa tttcttaaaa ctataattat acatcactgg
    26521 tgatttagag tgaccaaccg gtgtacctat taatgcaaat aatcctgttc tacctgaaat
    26581 ttccataact ataatctcct ctcaatatta tcattttctt tgcaaataac ctattcagtt
    26641 atttacaaag aaaaatttat ttattattta tatatttaat gctacttcaa aagcttcttt
    26701 tgttgcatct aatgccctac gagcttttac tgcatcacca acaatataag tttcttttac
    26761 aacttctttt ataacttcac ttaatgggtc gtaattacga gaacccatag caagtactac
    26821 tgaatcaaaa ccttttaaat catgctctgt gccatctgta agtaaatagt cgacaccatc
    26881 atcataaaat ttagaaactt ttgcaccagt aatggtatgt atattataat tttcaaaatc
    26941 attcataagg aatttacggt gttctgaaat tacatctgca ccaacttctt ctctaagctc
    27001 aataacagta acctcatgtt cttgttctcc aaggaaggct gccacttcac atccaaccat
    27061 tccacctcca acaacaagta cttttttccc acaagatttt ttaccatcaa gaaggtctac
    27121 agcatgaatt aatcctgaat cattgattcc tggtatagga agtacaagtg gagttgctcc
    27181 agtagctata ataactacat caggtgattt ctcctttata agttctactg tagcttctgt
    27241 attagtacat atttttacac catattgatt acattttgaa atataacttc taactaagtt
    27301 agtaatatct cctttccctg gaggatatgc agctaaacgc atttgcccac caagaacttc
    27361 agatttttca actaaagtta cattatgtcc tcttttagca catacccatg ctgcaagcat
    27421 acctccaaca cctccaccaa caacaagaac ttctttgcta atttcagctg gcttaagctc
    27481 tgcttcatgt cctaatatag gatttgcaag acaggctata ggtttgcctt ggaacatatt
    27541 tggtacacat ccttgtaagc atgcaataca tggtatcatt tcgtctagtt ttccattttt
    27601 agctttatta ggcatttctg ggtcagccaa gctttgtcta ccgaatgcta ctaaatcaca
    27661 tcttccttgt ctgaccatta actcagcaaa ctgtggctct gtataacgtc caactgttat
    27721 tactggtata ctaacagctt tttttatttc agtaactaat tctgcactga atccagcatg
    27781 taaagtcgta ggagcccaca tatattcatc atgtatatgt atactacgtg aaacatgaag
    27841 tccatctatt ccacaatctt ctagatatgc tgctattact gaactatcgt gtacatcaat
    27901 tcctcctgga acatcatcag tgctgtttat acgacataat attgctagag aatttcctac
    27961 ttttttacgt atattttcaa tgataagacg aggtaatctc attctatttt caaaacatcc
    28021 accaaactca tctacacgct tatttgttct ttgtgatata aaactactaa ccagatatcc
    28081 atgagcgcag tgaacttcaa cagcatctgc accagctttt tgtgcacgta atgcagcatc
    28141 tccataagat tctataagtt catatatttc ttctgttgtt attgctagtg gtgtattacg
    28201 accatttgat gcaggtattg cagaagcagc ttttaatgga tgtcctgcta ctttttcatt
    28261 tccttcagaa ccagcatgtt gtaattgtat agataccttc gaacctgcat catgacaagc
    28321 atctattaca tttttaaaac tatctattgt gctatcatca tataaacaag gcttacgagg
    28381 acctcctttt gcttttttgt ctacaacact agattctata gttattaatc caaaaccacc
    28441 taaagcacgc tcaagataat aagccttaga agtttcactt aaagtaccat ctgtgtttgc
    28501 aaaattgttt cccatagggg gaactacaaa acgatttgga actgtcattg aaccaattct
    28561 tataggtgta aacatagaac taatcttcat aaggttttcc ttcctttcaa gttttatatt
    28621 ataatactct gtatattttt atattatata agtttatttt ggagatactt cagaccatgc
    28681 tttatccaaa acttttttag ttgcattaaa tacagtttca gcagcagtgg ataacccttt
    28741 agatattaga gaatcagata ttacttctgc ccctatgact cttggtgata tattgtgttc
    28801 ttttattatt ttcacaaatt cctctgtgtt tccatatcct tcacctggag ccaaacggtc
    28861 atgtagtgat tcatccctaa gtttttcata aggagtttct aaaacatcac acacttgaat
    28921 tgatactatc ttatctgctg gaacaggtgc aaggtcctct gctgtctgct ttgctctagc
    28981 ccagtgccaa gtatctaata taagcattgc attttcacga ttacatcctt tcacaacacg
    29041 ccatgcagta gccaaatctg gtacaccact atatggcata aactcaagac ctataataag
    29101 ttcacctgct ctgtcacata attctcccaa tgcagttata atttgttctt ctggtatcat
    29161 ctctaataat ccacaattta tatgtttaac attaaataag tgagccatat gataaacatt
    29221 ttgctctttt tctctttgag cttccgttct atcttcttct cttccccatt gagttatata
    29281 ttctacttct gtaactttca tatcatattc attaagaatt gcaatcattt cttcatctgt
    29341 aacacctgca ttttttgcat caatataatt ttcagcacgc aatccaatac catcaaaccc
    29401 agcttctttt gcaatacgaa ctctatcacg gaatgaaact tctgttccca atgtataaga
    29461 actaattgta attggaatat taagattttt ttgattattc atagcttaaa tttgccccct
    29521 ttattttctt tataattaat agtatttttg attttatatt tttatttatc ctactagtag
    29581 tattatttta ccttaaaaat aaaagtattt tttgatttct atttatctag attttataaa
    29641 tttattgtat cacgagactt tactaataac aaattgataa tttcctatta attcatagat
    29701 tttgtttata gattttattt ataagataat tcttgtattt ttctattagg tcgtataaat
    29761 atatttatct tataattcag acaaaaaacg ataaattttt ttaaaagctt ttattcttac
    29821 tctataatca tatataataa aaatgtaaaa atatcttaaa ggttaacttc tacaaatata
    29881 taaataaaaa tacctatgaa aggatgaaca aaaattgaat ttatatcact tacgctattt
    29941 tgttacattg gcacatttag aacactatac aaaagcggca gaaaatttat ctataacaca
    30001 accaagctta agtcatgcta tttctttact agaaaatgaa cttggggtgg ctctatttga
    30061 aaaagaaggt agaaatatag tccttactaa gtatggaaaa atatttttaa aagatgtgga
    30121 aaaatcatta gaaattttag attcaagtgt aaaatcatta aaaataactg gtactggtga
    30181 aggacaaata gacttagctt ttcttagaac acttggtact gattttatcc cagacatagt
    30241 gcacaaattt ttaaaatcta atcctgctaa atcaatagat tttaaatttc atactggtgt
    30301 aactactgac attattcaag gtcttaaaga aagaaaatat gatattgcat tttgttcgaa
    30361 acttgaaaaa gaaaagggaa ttgaatttat acctgttgcc aaacaagatt tagtactaat
    30421 tgtaccatat agtcatccac tagctgcaaa ggatactata gatttaaaag aaaccatacc
    30481 ttatcctcaa atagtattta atcagagaag tggtcttaga tatataattg atgatatgtt
    30541 taaaaaaata aatcaacagc ctaatatagt ctatgaagta gaggaagacc aagtaattgc
    30601 tggattagtt gcaaaaaatt tcggaattgc tgtagtccca aatatgaata tgcttagctt
    30661 tacaaaagta aaagtaattc agattattca cccaagttgg gaaagaaact tttacttagc
    30721 atttataaaa gatagatatt tgcctcctgc aattaaaaac tttaaaaact ttgtcattaa
    30781 aaacgctcaa ttataattta ttaataaagg ggttattttt aaatatcctc ttttattctt
    30841 tttataaaat aaaaaaatct atacttttaa aagtatagat tcctaactga cagtcggcat
    30901 ccgagtctca gtaattatcg ttatacaaca gcaactggat tcagttcctg aataactagg
    30961 ttacttacat tatatcagat tttttaaaat ttgtcaattg tatctaacgc attttttcaa
    31021 gccatggtcc aacaggctct acaataggaa cttctttaaa tccccaattt cttatatcat
    31081 tcacactcgt tggagtatat attttgtttc tgacagattt gaatattttg tttttttctc
    31141 catattgcat acactttgga ttagcttcta ttaaccctct tcttgctctg ctaagaggat
    31201 tacataaaat atctgctatt tctaaacctt ctctatagtc agcatcttct tttttggcaa
    31261 ttataaaacc cttaacctta tctcttaatt cttcatctat atctaagtat attgttccat
    31321 tattaaatac atcaaaaaac gccttttgta cttttaagtt tgagacatca tcccttgact
    31381 ctataactat tcgtgcagat tctacagttt cattatttac aaatgaataa aaattctgaa
    31441 gaacatgtat aaaagccaca acatacggtt cctttgaagg tgcataatat ttctttaatc
    31501 tagctttatc tactgttact gatattatag tacactctaa tctagataga aataaaggca
    31561 actcatcata gaataactta atctgtgaat catcaaactt ctcaaatgct cttgattttc
    31621 ttgatatatc tgtcaaatgt attcctatgt tactggttcc aaaacaatac tctttaaatg
    31681 catccatttc tttcctcaaa gaacatacat aatcgccttg acttactgca tatttatatt
    31741 caaaaattac tcctgtcaat gtaaatgggt cttcatgatt tatatcagct cttccacttt
    31801 catcaataaa cattatatat tttttcttta taatcttact caccctctta acatatgatg
    31861 atagcatcta tattcatttt atatgagttt taaaaatatt ccaagatttt tatataactt
    31921 aaacttaatt ttatactaaa aaattgagat gtaaaacaat caagctttta ttgattgaat
    31981 ttcacatctc aattataatt atttttcaat atatattttt actattttgc aagaatatcc
    32041 attaatttat ccattactat ataagatact ccgcctccta tttgataagg agtttcaact
    32101 tttttatttg caaatactct ttgttgctct gatgataatc ctgaattatc cattaaaact
    32161 attggtgaat gtaattttac agctaatggt ccagctgata aagcatctac taaagcatct
    32221 gatttactaa ctaatacagc ctgtaaatca gtatctccat agaatttttc tatcactttg
    32281 gcattagtat ctactctact atctccatat attctatttc ctgaaatatc ttcagtagtt
    32341 atatcattca tttttgctat tactgaatcg ttaattgcac ttggtccacc tataaagtat
    32401 gcattttcta attttctttc tgttagccat ttataagatt cttctgtaat tccatcttta
    32461 ttgactaata ttataggttg tttttcttcc ccagctttag aagctacaga taaagcatct
    32521 gcctccccat ttccagaaac catatatgca gtttttattt cttctcgatt tccaagttct
    32581 tcagctattc ttgtagcagt ttgatatcta tcttgacctg ctattctctt tgtttctgtg
    32641 ttgaaagtag tttttatttc ttgctctaat ttagaactta ttgcattttc tccacctatc
    32701 aagattactg ttttaggtgc taataacttc atttcttcaa cagtttcagt tggtaaatta
    32761 gctgtattag taagtagtat tgttgagtca tagctacttg ctaaaggagt tgctgttata
    32821 ccatcagcta ttgcattacc atttactaat attacagtat ctgaactatc agcattccag
    32881 tttccaactg aacttatctt tttagctgta tcaaatctat ttgcacctat aattgtatcc
    32941 catgtaggat ttatagttcc atcttcatta aaagtataat ctttcccatc tattttttga
    33001 gaaccagtta gcatctttcc atctttgtct aaatagtaag acttaccatc tatttgttgc
    33061 catcctgtct gcattattcc tgttttgtca aagtaatact tattaccatc tatttcttgc
    33121 catcctgtta ctgctaaacc atcagatcct agatagtatt tctttccatt cttttcttgc
    33181 catcctgttt gcattactcc atctgagtta aagtaataag tttttccgtc tattactttc
    33241 catccagata ctcttgctcc atcagttcct aaataatatt ttttgttatt aattgttttc
    33301 catcctgttt gcattactcc tgaagcatca aagtaataca tttttccatt tacttttagc
    33361 caactattct tttggtatgt tccatcagat tttacataat acttcttacc attttctgtt
    33421 ttccatcctg tttgatttag atttatctta tattttgccg ctatctttac atagctgtcg
    33481 ttactataat ctataattac atctgaacct acaggaactt ggtcaaataa ccatctaaca
    33541 tctttattgt gcattcttat acatccacca gaaatatgct ttcctataga actctcatta
    33601 ttatttccat gtattccata tgtatctcca taagttcctt ttaatgctaa tcccatccat
    33661 ctatctccta atggatttct tggacttcct ccaggtatat tacctttata atatggtcta
    33721 ttttttatct tgttaactac ttttgttttc cctgttggtg tttctgaccc ctttttacct
    33781 gttgcaactc taaattcttt tacaagttta ttatttacaa aatatcctag agtatttttt
    33841 cttgaattta ctataatcac atgtttactg gctgcgcttg attctggtac gccacatgca
    33901 aatactaaaa ctaaagtcag tgctagtact aaatactttt ttagactttt tttcactata
    33961 acttccccct cttttagaaa cattactaca tgtgtctaat tataacataa aattaccaat
    34021 accttatatt tacaaatttg ttacatttat acatataagt atgtattcta ctcttcatac
    34081 ccattaggat tcatactttg ccatctccat gaatcttcac acatctcttc aagttcatac
    34141 ttagctttcc atccaagctc tttttctgcc tttgaagaat ctgcataaca catggctaca
    34201 tctccagccc ttcttcctac aatcttatat ggtatttctt ttccacttgc tttagaaaat
    34261 gcttttacta aatcaagaac actatacccc tttccagttc ctaaattata aacaacaagt
    34321 cctggatttt cttctaattt ttgtaatgct tttacatgac cagcagctaa atctaataca
    34381 tgtatatagt ctctaactcc agttccatca tgtgttggat agtcattacc ataaacactc
    34441 aattccttca atttacctac tgctattttt gttatataag gcattagatt gctcggaact
    34501 ccatttggtt cttcacctat tctaccactt ttatgagcac cgactggatt aaagtatctt
    34561 aaaagagcta tatccaatga cttatctgct tttgatatat ctactaacat ctgctctatc
    34621 ataagtttag ttcttccata tggattggtt acagaaagtg gaaaatcctc taatatagga
    34681 caagtatgtg ggtctccata tacagtagct gaagaactaa atacaaactt tttaacacca
    34741 tattctctca ttaattcaaa taaatttaag gtacttatta gattattgct gtaatattca
    34801 attggttttt ctactgattc accaactgct tttaaagctg caaagtgtat aattgattca
    34861 atattatttt ctttaaatac aacatgcatt tcatctttat ttctgatatc aatattataa
    34921 aattttactg gttttttaga taattccttg attctatcaa ccactattga gttgctatta
    34981 cttaagttat caactataac aacttcataa cctgattcta aaagttctat tgctgtatgg
    35041 cttcctatat atcctgctcc tccagctact aaaactgcca ttgtaattac ctcttttcta
    35101 atatttattt ttcacttact ttttttctca tatagtccat taaatcatct tttaaatttt
    35161 ctctctttag agcaaagtct attgttgcct ctaaaaaacc aattttatct cccacatcat
    35221 atcttctacc ttcaaagtta taagcataaa tagcctcttg ttttccaaga gtttgaagtg
    35281 catctgtcag ttgtatctct ccacctttac caggtgtctg tttctctaat atgctaaata
    35341 ttgcaggagt tattatatat cttccaagta tagctatatc agatggagct tcttcaattg
    35401 caggtttttc aaccatatct ttaactttat atactctatc ttcaatatgt tttacatcca
    35461 atataccata tttattagta tcttctttag ctatcttttg aacacctaat acagttgttt
    35521 tatactcatt ataagtatct attaattgtt ttaagcacgg aacatctgaa tctactatat
    35581 catcacctaa taatacggca aaaggttcat cacctataaa actttttgca cagtaaattg
    35641 catgtccaag accttttggc tctttttgtc ttatataatg aatatttacc atatttgata
    35701 tgtctcttac catttctaac atctctgtct tacctttttg ctctagttct aactctaatt
    35761 caactgattt atcaaaatga tcttctatag attttttatt tctacctgtt attataagaa
    35821 tttcttcaat tcccgattct atagcttctt ctattatata ctgtaaagtt ggtttatcta
    35881 ctataggaag catttctttg ggctgtgatt ttgttgctgg taaaaatcta gttcctagcc
    35941 ctgctgctgg tattattgct tttttaactg tcatctgcat tttttcaccc ttcttcgtaa
    36001 attttctatt gtaccaaatt aatataccat atttatactt tttcttcaaa ctctatatta
    36061 tcccaatatt taatgctata agataatata aggtagatga aatttcatct acctttagtt
    36121 ttataagtta atattgtatt gtttatattt tatccaaaac ttatacaggt actaaatttc
    36181 atctaagatg ccttttatat cactatctat atcttcatct agataagaat ctaaatcttc
    36241 taagtcaact tctagttctt gatatgtcat atcaacactg acatcctcat ctatatccat
    36301 ttctgatatt aattctccta aaatactatt tccatcagaa tctaaaccac tatctatatc
    36361 ttcatctata tagttttcat ttaaaatttc atctaaatca atctcgtaat aaacttcatt
    36421 atttttttca tcccctgagt ccaatcctaa gaactcatag ttaaaagtcc aaacattgta
    36481 tttacttgac atactttatt cctcctgtga aaaacatatt ttcatctagt ttattggttc
    36541 cataatcaac agagttatat attttttcaa ttatgtcttt tcttctttct tttgtactat
    36601 tatttaatgt caattgttta aatacatatg tatttgttat tctctcgaat aatatttctt
    36661 ttatactatc atcatcaata tttctatagt ttttccacaa taactcaaat aacttaaaca
    36721 tttccctact agtttcatct acataataag gatacatatt ttctactaaa tggtttaatc
    36781 ttgatatggc ttgttttaaa aatacatcaa gacttgcact ttcactttct tttaacattc
    36841 tataattgta tttcttctta tcttctcctg aaattacaaa gatgatattg tctaaacttt
    36901 tttcaacttc atttaaataa ctgcttatat tatatgataa atcagacaat agatttttaa
    36961 tctgcttaaa cacttgtaca tcaagtttag tattatactt ttcaaacaaa tctatttctt
    37021 gattttctaa tattcttggc atatatgctg acaataaatc taaattgttt ctttgttctt
    37081 gtatttgctt ataaagtgaa tttataactt ctattcttat ttcatcattt aactcttttt
    37141 ctaaaatctt atcaaattca gatttcatat agtaaatatt tccaaagaaa ttaaatatta
    37201 tcatatcatt catagcttta gaccaattct tatatatcac ttcaatagaa ttttctttaa
    37261 gtagaggttg ctttgcatat ataaatacat cttgcataag tttttgaacc atacttttac
    37321 ttaagtttaa aagtactttt tgattattaa attttatttc cgtttctaca aaattagaat
    37381 tttcgttttc aagttcttta ttaattacaa tgtcttttat atcactattt tttatagata
    37441 tgatttcttt ttgaaaagac tttagaatag tcaagctatc gaaatcttct tgaataaaaa
    37501 atggagcatg ttttaatgta tatcccacta tttcattttc tatatctttt aggtcatcta
    37561 tttgcataat ttctctattt ttatcattta tatgtaggtt aaatacattt ttattatcat
    37621 ataatattat atcttctcct aaatttaact tagaacaatt atctttcgct gactttacaa
    37681 tagtcttctt agatttctta tttataaaaa ttaattggtc ttgatatttt actaaaagca
    37741 tgtttgtgtt tttataatca aatccatcta tatttcctga tatcttgcag aatactattt
    37801 cacaatcttt aggaagattt cctatttttt ggttatcttt aactctctca tttaaatcag
    37861 atgggactac actatctata ttgttattaa atatagatac agaccttact ataatcccct
    37921 ctctttccat atgaaagtat cccttcaatg acactctttt atcttctaaa atgtatcttt
    37981 ctatatcatc aaaatttatt tcaaatctat ttttcccact gataaatata aacttctcat
    38041 tatctttatt aattccaccc atataaaact tattgtcatc taaacttaat atagtcatat
    38101 tatcctttag atagaatata aattctcttt gacttttgca gattaaatca tattcatcca
    38161 aagttatttt catagtcaaa tttgctgtaa catttttact tgaattttca ctttttatgt
    38221 aaaaaggcaa gttatttcca tagacaatta tttgagaatc ttctaaaact gcctctaatt
    38281 tttctttatt gtctgaaaaa ctatatatat attttacacc tgtatcctca ttaacttcat
    38341 ctgatttgct gattattata ttccctagat ttgttatatg aagcttttta tattcttttg
    38401 agtatctact tatgccacta agctcaaacc catctgaaag ctcatatatg attttttctc
    38461 ctaatttcaa cataccttca ccacctaaac agaattataa gtattttata aaggtgaata
    38521 aaatgtctca aaacaaataa tatttttttt aatacttttt attctgagac atagtttctc
    38581 cttttttata atgctctaag caccttcaac tatttcttca taaagtttat ctaaatgttt
    38641 aacatattca cgatatccag atttgttctt taactcactt cttaaatctt catatttttg
    38701 tttaagttct tcagcactca aagaaggagc tgattctttt aattcttcta acttataatc
    38761 atagtactta tcatacatag ctatatatgt atcaatagac ttcttagcta gttcattaca
    38821 tttttcttgt gcttctccat attgagaata atcacctatt tttattttat agtatccatt
    38881 ttcttgaatt attgttgaag aaataccttt agcttcatat tcttttgctg tttcttttgc
    38941 tgttttttca actttaagtg aacctgcata aacagtgtaa tatacacctt taccatcttt
    39001 atatgcttcc atttcttttg ctttcttttc agcttgtgct ttttcttgag cctctttttc
    39061 agcttttgcc ttttcttctg cttctttttt ctctttttca gcttgtgctt ttttctcttc
    39121 ttcagttaat ttattgttag cttgttgttg agttgatgac tttggaatat tctctttatc
    39181 atttttctta ttgttgccta ctgttataaa atatcctaca ccaacaataa ccactataac
    39241 tactgctata atagtttctt ttaatctact cttcttagaa acaacctctt catcatctaa
    39301 agaatcttct ttatctgata cataattttt catttctttc ttgttttctc tatatttgtc
    39361 cttagaagaa tttttagatt ttttattact attttctttc tttttaatag gtattactac
    39421 tgatttttca ttttctaatt tttcttcttt tatttctttt gcttttttat cttctaagtt
    39481 tttactttct ttttcaagct tcgattcatt atttgaagat actttttcat ctaagttatt
    39541 atttattggt ttttctattt ttacactacg ttcttcttct atatgttgac ttggttcttc
    39601 ttgttttatt tctttcaatt cattttgctc tatttcttct gatttcactt gatgattttc
    39661 aactggttta tctaaaatta tatctggaga aatatcattt aaattctctt cttcttgttc
    39721 agcttcttca ttgtcttttt taataaatcc aaataattta gccttctttt tactcttttt
    39781 attttctggt tcaattatat cttctttatt gctgtcgtac tctttatctg tagtatcttt
    39841 atcttctaca acgtcaccta tatcttgatt attactatct acttcttctt tagtcccttc
    39901 ttcagcatca tcttctattg aaatactact tctaaagcaa atatctttat ctgcattttt
    39961 tatcatgtaa atgtattctt caatatcgat atctttattt cttctagttc tttttgatgc
    40021 aatttcatga ttttctaatt cactatagtt atcttttatt agattctgtg ctttattcca
    40081 tgtatcttca ctaatttctg ttttattttt aattacatag tccacaaatt ccttaaaatt
    40141 ttcaggacca aattctccaa ttatagtcag tctcattgca ccttctataa ggtctctatt
    40201 tcttctcttt aaaaattcta atacaactgt tgcacaagca aaatctttaa taatttcttt
    40261 gccaaaacca tatgcttcaa cagaatgaag ttcttctaat ccacataact tcttatattc
    40321 attgtgtatt gtttgagata tactttcatt atttaagcta tttaacttat ctataaactt
    40381 cgattctata tcatttgatt ttgattcatg ttttactttt gaatttttaa tttcatttag
    40441 tagcatgtca ttttctgaat tatctttacc taattgcaaa tcctcaattt cagttgcttt
    40501 tatttctact ttgttttgtt cgttattctc ttccacatta ttaggtacca catctttatt
    40561 actagctaat attttgttta cacagaatat aatttctctt tttaattctc ttttcgcatc
    40621 tgcttgattt ttaagaaata aatctccaca ttctttcttt tctaaactta tttttctaag
    40681 agatatatta agaaggtctt tatataggtt taaaacctta taatcctttt ctaaacgtct
    40741 tcttctctct gatagttcca ttttatcata agctaaaaaa ctatttaaat cattggcttt
    40801 tagagagtct aatccctctt tcatagcctt atttacatac tttctacatt ttgctgtagt
    40861 taactctaaa tctttttcta attcatctat ttcaggtatg tacttatcta ctatccattt
    40921 gccaataagt ggttctgtat ttcttgctaa tgtcttataa aacaatatat taaattttaa
    40981 aagctctgca tattttgctt cattaaattc tactttttca aatttctttt ccaaaacacc
    41041 atctagcttt tcatttattt tagactcttg ttttaaaaaa cttgctgtga catttaaaac
    41101 agtgtttctt attatattat tttcactcaa aaccttcact ccttaaatca attattttat
    41161 tgtaatattt acattgtgca aagttgctaa tttgattatg atatctaaat aattatttac
    41221 taaatttgct acatcttata tcatatcata ttatttacat cattttactt tttcttttta
    41281 tatctatctt atattatacc atttttaata tctgtactaa cttatattac aatattcctc
    41341 aaaattttaa aagtagatta gacaaattta caaataaaaa aacatcagtt taaactgatg
    41401 tttttgacta tcgaaataat taagcaagtc tataagcgga gttctgtatt agataatcat
    41461 ctttctaggc ctattgtcac caataggctc aagcgaccta cctaccggag agtacgagca
    41521 gcactcttta ttcctatctt ggtcttgctc caggtggggt ttacatagcc aactagtcgc
    41581 ctagctgctg gtgagctctt acctcgcctt tccatcctta ccacaatagt ggcggtttat
    41641 ttctgttgca ctatccttag gatcgctccc actaggcgtt acctagcacc ctgctctatg
    41701 gagctccgac tttcctcatg taagattaca tgcgattatc tggcttactt aatatttatt
    41761 ttacttagtt atgttaacac aaattctttt acatgtcaaa gtaatattat actaaaaatt
    41821 taaatttatt caaaaatagt gtaatataga tatataaact acatttaact cgaggtgatc
    41881 tattgaaaaa attatataga atagtaatta acattatact agtattagta atactttaca
    41941 gtggatttaa tatatactca aaacttacca aatacaatca tgatactaaa atatcctcag
    42001 aacttcaaaa aaaagaatat aaaaaagagg atttatcaaa gattaacagt gattttaaat
    42061 tttggctttc tgttgagaat acaaatataa attatccagt tgtacaatct aaagataatt
    42121 cttactatct tgacaaagat ttttataaaa aagattctat ttctggtaca ctgtttatgg
    42181 attatagaaa taaatctatt gatgacaaaa atatcataat atgtggacat aatatgaaaa
    42241 ataaaactat gttcaacaac ctaaataagt ttaaagatgc tgacttcttt aaaaaaaata
    42301 ataaaataaa aataaccttg aatggaaaag aatttttata tgatgttttt tctgcttata
    42361 ttgtagaatc tgattatgat tatctaaaaa caaattttaa caatgaatct gattatcaaa
    42421 attacataaa tgatattact tctaaatcat tgtataaatc tcctattaag gtaaatagca
    42481 atgataaaat agttacactt tctacatgta cctatgaatt tgatgatgcc agaatggtga
    42541 ttcatggtag attgatttaa aactcacaga cacagtttaa aacaataatt ttaaactgtg
    42601 tcatctttta tacctataat ttgtaaatta gaccactaaa agtatttaat acaaaataac
    42661 aaatacatca aacaataaaa aacaataaaa aaagactatg ctaaaaacat agtctttact
    42721 ggagctggtg ataggaatcg aacctacaac ctgctgatta caagtcagct gctctaccgt
    42781 tgagccacac cagcacacct attttattgt aaattagcaa aactaatttt taaaagtta
//
LOCUS       DAFAZV010000036        41650 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFAZV010000036 DAFAZV010000000
VERSION     DAFAZV010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41650
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.036"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            114..1403
                     /locus_tag="KOU88_002627"
     CDS             114..1403
                     /locus_tag="KOU88_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBK3212496.1"
                     /translation="MRELLKVTLIVMLVLINAFFVACEFAMVKLRSSRIDTMITEGNN
                     NAKRCKIIKDNLNSYLSACQLGITLCSLALGWMGESTVKELILPIVSVFNLSESIIYT
                     ISISISFLIITMMEVVIGELVPKALALYNTEKIMLSTSFLLVGFYKLTYPIIYFFNLS
                     TDLFLKPFGYSQADEVDEPHTGDEIRLLVEESYKSGLIDESEQRLVDNIFEFEEKKIR
                     EIMVPRTDMVCIYESDSEEKILAILKEEGVTRYPVCRKNKDDILGFVHIRDLYNQKIN
                     ENKIELEEILRDIIYISENLTIDKALERIRKEKLQLAIVVDEYGGTSGVVTIEDILEE
                     IVGEIQDEFDKEETHIKKIGAGSYLVDGTESINYINKYFGLDIEHDGFDSIGGWISYM
                     LGSNIKVNQSVTFENYNFTILELDKLRVVKLIIKSVI"
     gene            1432..2112
                     /locus_tag="KOU88_002628"
     CDS             1432..2112
                     /locus_tag="KOU88_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK3212497.1"
                     /translation="MQKVEGIIFDMDGVLFDSERISLEFWMETFEKYGYTMTKEIYTS
                     VMGRNRKGIIEGLTEIYDSSVPIIDLYDEKTKNMIEFMERKGAPIKLGVNELISFLKE
                     NGYKMAVATSTKRERAVKRLAKANLKDYFDAIVCGDDVVNSKPNPEIFLKAAKKINVN
                     PKNCIVIEDSPMGVEAAYNGGIRCINVPDLKEPDEQIKSQSHKILETLLEVREYLKSL
                     NSKECHNL"
     gene            2213..2752
                     /locus_tag="KOU88_002629"
     CDS             2213..2752
                     /locus_tag="KOU88_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative ABC transporter permease"
                     /protein_id="HBK3212498.1"
                     /translation="MDNVGSLLYFLFNFFLYGFIGWIIENLYSYYKQGHFQEDGFLNG
                     PFKPMYAIAMSIIIEVSRFIDPNNIFALLLLCLVVPTVVEYITGILMKVYFNKVYWDY
                     SDYKYNSRGIVCLKFSVYWTILTFIGVRYFQVYIVDSLYSLIIPYWPIVVTILLVTLF
                     VDEILTIKFLRGNKDIVER"
     gene            2928..3947
                     /locus_tag="KOU88_002630"
     CDS             2928..3947
                     /locus_tag="KOU88_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK3212499.1"
                     /translation="MMGKIRFGIVGTSNIANIFLRAASRVKDFELVAVYSRNLEKARE
                     FGTLYGASIFFDDLEQMAKSKDIDAVYIASPNALHSKQTITCLKHKKHVLCEKSLASN
                     LKEVKSMIKTAKDNNVLLMEAMRITCVPNFKAVKENLYKIGKIRRFFGSYCQYSSRYD
                     KYKNGIIENAFKKELSNGALMDIGVYCIHPMVNLFGAPKTVKAVSHILQTGVDGEGSA
                     VFQYDDMDAIIQYSKVADSYIPSEIQGEEGSIIIEKLNLFEKAIIKYRDGREEDISIP
                     KEKAEEKPREIEGMYYELVEFISLINNNKIESNINSHENSIIVMEIMDEIRRQSSIVY
                     PADSI"
     gene            4235..5425
                     /gene="dltD"
                     /locus_tag="KOU88_002631"
     CDS             4235..5425
                     /gene="dltD"
                     /locus_tag="KOU88_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBK3212500.1"
                     /translation="MRKLIYFITPFIIGVVFLFGLDKFLDSKTDELLREKNLLPIMDD
                     TLSDIKDKGVTANNHFLREKDIMILGSSELSNSTKQHPKYYFNTNRSKNKVFAIGRAY
                     TQTLQDAAILGSMNPNIDNKKVVLLISMQWFMEKDGVTSHHYQSRFSPIQFYRFLDNP
                     KISKQNKIEYAKKSSKLLWGSDEYKAEALYAKLYEPKTFPEKAEKVLLEPYFQGRKYC
                     IALKEKGILYKRLIKLDKKRATKRKRPINWSYERKKAIEDAKKRVGKNPLNIDKYYYK
                     EHFKDGIEQYKGRDKDVNLLTSKEFENYKLMLNVCTDLGIKPVVVLIPSMDKFYNLTG
                     ISEKERNQYYDKAQKIAESKGFEVLNLKDKGSDKYYLRDVMHLGTKGWVDVCERLFKI
                     FKEQ"
     gene            5546..7060
                     /locus_tag="KOU88_002632"
     CDS             5546..7060
                     /locus_tag="KOU88_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase"
                     /protein_id="HBK3212501.1"
                     /translation="MKIIEGIKKYSNTDRTALMCNGDKLSYKDLNEYSDAISVFLKDV
                     YKEEDTPIVIYGNKENMIMACMIGALKSGRAYVPLDISFPIDRVFEVTKEIKPKVLFN
                     FSDERNFGDINVIDMDKLNYIINEYQGKSLDKENWVKDDENAYILFTSGSTGKPKGVQ
                     ISSNNLDSFSDWISPYLNIDGSEKVIMNQPAYSFDLSVTTIYPGLIHGATLFSISKDV
                     LADYKELFRQFSISDIAVWVSTPSFAGVCITEKEFNSKMLPNLESMIFIGEALSKNLT
                     KELMSRFPNTRIINGYGPTEATVGVSVNDMTQKAIDDEKSLPVGYPMSNCKIKILDED
                     GNELKENEKGEIIIIGPSVSKGYFNNKEKTDEVFFYDEIDGVKWRAYKTGDMGYLLDG
                     NIYYCGRKDFQIKLNGFRIEIEDIENNLRKVHNVKNAVVLPVYKDEKIAYLKGIVELN
                     EKNDLSNIKNGMIIKKELGKYIPSYMIPRNISIISEFPTNINGKIDRKKLMEEI"
     gene            7060..8208
                     /gene="dltB"
                     /locus_tag="KOU88_002633"
     CDS             7060..8208
                     /gene="dltB"
                     /locus_tag="KOU88_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBK3212502.1"
                     /translation="MIFSQYGDYFYLYILLLTSIPAVILGLMGKNIKYYGMLASLFMI
                     FLIVGIDVQLKYLVIFIILEVIIVKGYEYVRRKTKNKYIYWGFLFASMLPIIINKISP
                     VTSFGIIGFIGISYLNFRTIQMVIEIYDGAIKEVKISKMLYFMLFFPTLSSGPIDRSR
                     RFEQDLEKQISRKEYIEEYLLPGIKNIVMGVGYKFVIAFLINTYWVSRIPKDMSFINI
                     LSYMYAYSLYLFFDFAGYSLFAIGTGYIFGIQVPINFDKPFISKDMKEFWTRWHISLS
                     RWFGDYIFSRFVMSSMRKKRFKKRTTAAHVAQMITMITMGFWHGLTWYYVAYGVYQGL
                     ALVLTDIYQRKSKFYKKHKKDKWFERVQIFITFHIVCFGLLIFSGYLA"
     gene            8227..8457
                     /gene="dltC"
                     /locus_tag="KOU88_002634"
     CDS             8227..8457
                     /gene="dltC"
                     /locus_tag="KOU88_002634"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBK3212503.1"
                     /translation="MQETVIEIFEDVLGTDEIREDLDLNLFETELLDSLAIIEVLLEI
                     ENRLGIELQPTDLERKDMSTVNNLVKFLETRK"
     gene            8674..9459
                     /locus_tag="KOU88_002635"
     CDS             8674..9459
                     /locus_tag="KOU88_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK3212504.1"
                     /translation="MSLNSIDRKKEILKLLDSKGKVNTKELVKRLEVSSETIRRYLEE
                     LENENKLKKVYGGAIKINYGVIEPEHIKRNNTNLDKKQSIAKYAAKFVNDNESIIIDE
                     GTTNLQIVDYIISVNNLKIITNSYPVLSKLISYENQGLFDGEVIFIGGKVNLKHQRTA
                     CPISIDAMKNLYVDKAFISSEGILDSFGISSIDQNKALLSKAYIKNSKESFVLCDSSK
                     IGIASMYKIADLEELDFVICDVEPPNEWKDKLNEINITWIEAK"
     gene            9738..11648
                     /gene="phnW"
                     /locus_tag="KOU88_002636"
     CDS             9738..11648
                     /gene="phnW"
                     /locus_tag="KOU88_002636"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBK3212505.1"
                     /translation="MKKIYGEKIKAVVFDWAGTTVDYGCFAPLNVFIEIFKRRGIDVT
                     MEEARKPMGKLKIDHIREMCEMDRIKNIWSDKFGKVPTEDDVNELYAEFEPMLFETLE
                     EYTTPIPHVVETIEKLRKNGLKIGSTTGYTREMMNIVEPNAAKKGYSPDFLVTPSEVS
                     QGRPYPWMCYKNAEALGVSPMSSMVKVGDTISDVKEGVNAGMWSVAVIKGSSELGLTQ
                     EEVENMDKEELKAKMSIVSKKFKEAGAHFVIETMAELEDILIKIENETIKSDFVPEND
                     YILLTPGPLSTTKSVRASMLKDWCTWDVEYNNLVQDVRRRLVSLATQNTDKYTSVLMQ
                     GSGTFSVEAIIGSTISKDGKLLVIANGAYGKRMKDICNYLNIEFVDCTFKDIEAVDLN
                     VVENLLKENKDITHISMVHCETTTGRLNPIQEVGKLAKEYNKIYIVDAMSSFGGIEID
                     VEDFNIDFLVSSSNKCIQGVPGFGFIIANKEKLSKCKGIAKSLSLDVYVQWETMEKNN
                     GKWRFTSPTHVVRAFYQALLELEEEGSVEKRYARYKENQFTIASRLKSLGFDTLVNDN
                     AQSPVITTFLYPKNAKFEFMEFYTYLKDNGFVIYPGKLTDIDTFRIGSIGEVYPTDME
                     RLADVIEKFINR"
     gene            12007..12828
                     /locus_tag="KOU88_002637"
     CDS             12007..12828
                     /locus_tag="KOU88_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212506.1"
                     /translation="MNEELSSLRFDGVGKCKGGIFDNVNISGTGKIEGSVKCSKFDSS
                     GSAKVFGTTECNEFFTSGLSKVEGNILASKVEISGLLRCTGNINSVEIDTSGIINVEG
                     SIKSDIIHGEGYLKANENIDCENINLSGILECNGFLNCEEVNISLNGTSNFNEVGASS
                     INIKKGHGDYCKKFRMLEKKHINFEKVSSNLISLGLLSIRKYTESKLFANIIEADEIS
                     LENSEVKVVRGKNIKIGKGCYVESLEYSESIEIDEDSIVGEIKNISEKIKLKKDK"
     gene            12869..13636
                     /locus_tag="KOU88_002638"
     CDS             12869..13636
                     /locus_tag="KOU88_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymer-forming cytoskeletal protein"
                     /protein_id="HBK3212507.1"
                     /translation="MEKGSIKILGEGFISSGEYENIKIVGSSKSKGNVKSNEVKVLGD
                     AKFEGDINIKNFVVNGKTIIRGNLKAERVRVNGQLNIEGDAEIDDLVITAQQKVDGKL
                     KCNNVTIRGQLSVNENMYAQDIKIYGEMRNKSNIECEDIKVYGVIKCDGLLNGENIYV
                     YSGGGSYCKEIGATNIKIGRSKDAFSLIKIINIFSGKFKCNLIEGDTIELEDASIKDI
                     RGKSISLVDNCDVGNIEYSDNLSVSDNSTVKNSIKVG"
     gene            13644..14264
                     /locus_tag="KOU88_002639"
     CDS             13644..14264
                     /locus_tag="KOU88_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbD family protein"
                     /protein_id="HBK3212508.1"
                     /translation="MEELISKKDLLSKTNISYGQLYRWKRKNIIPEEWFIKKSAFTGQ
                     ETFFPRDKILERIELILSMKEETSLDDIANMFMKKDINKEFDIDFILSKEVICNYTKE
                     IFQNLYKKEQSIGKKELLILSIIEKFLVKSIITFEELKLIVNIIEENFTSIYNESGKI
                     YLFRKFGVPFVVGCLDYKKVKFEKDVVKIIEVDLTKEINDISIKLS"
     gene            complement(14564..15151)
                     /locus_tag="KOU88_002640"
     CDS             complement(14564..15151)
                     /locus_tag="KOU88_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rubrerythrin family protein"
                     /protein_id="HBK3212509.1"
                     /translation="MNLKDSKTKENLLRAFAGESQARNRYNISASVAKKEGLYIIESL
                     FNYTADQEKSHAKQFFSKLKEFAGENISISGAYPVDLYDKTAQHLKAAQHNELQEWDD
                     VYKNFGKTAREEGFESIAKLFENIAEIEKVHGDRFGRYATDLEEGTLFRRNEDIQWIC
                     THCGHIHIGKEAPKACPVCLHPQGYFLDFKNSLFE"
     gene            complement(15237..15674)
                     /locus_tag="KOU88_002641"
     CDS             complement(15237..15674)
                     /locus_tag="KOU88_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3212510.1"
                     /translation="MEDKYIVHFISKTKASMIKFIENKLSKNGLGELIPTHGNILTAL
                     YENNGILTMKEIAAKIGKDKSTVTVLVNKLINLGYLERQKCTNDKRITYIKLTKKALL
                     IEDTFNSISTQVKETAYHNITENEKQEFLRILKKINDNFKNAD"
     gene            15778..16776
                     /locus_tag="KOU88_002642"
     CDS             15778..16776
                     /locus_tag="KOU88_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdH/YhfP family quinone oxidoreductase"
                     /protein_id="HBK3212511.1"
                     /translation="MNKKFKSLYITEEEGNFRRNIVEREVDTLPEGEVLIKVKYSSLN
                     YKDALSANGNKGVTRKYPHTPGIDASGIVESSSCDDFKIGEEVLVTGYDLGMNTSGGF
                     SEYIRVPSSWVVKLPKNLSLKEAMDYGTAGFTAALSVYKFIDSVDKNMGDVLVTGGTG
                     GVAVIATKILIKLGYSVVVSTGKLEEQKEVLLNLGVKDVIHRSEVDDNSGRPLLRPRW
                     AGVIDTVGGNTLATAIKTTNYCGAVTTCGNAGGVDFTSSVYPFILKGITLYGIDSVDC
                     PMNLRLKIWDLLSNEWKLDDLDDMVNVVSLEELNDSIDSIMAGKHVGRTVVDLEKI"
     gene            complement(16896..17822)
                     /locus_tag="KOU88_002643"
     CDS             complement(16896..17822)
                     /locus_tag="KOU88_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBK3212512.1"
                     /translation="MSKENKNVRIAVVQASPVIMDLEKTVEKALGLIKEAGRKGANIV
                     VFPEAFIPAYPRGLSFGFVVGSRTMEGREDWKRYYDNSVPVPSATTDLLGKAAQEAGV
                     YLSMGITERDGNDINCTLYCTNLFFSPEGKLIGKHRKLKPTGTERCIWGEGDGSTLTV
                     VDTPYGKMGSLICWENYMPLARTALYAKGVKLYIAPTADSREEWQATMKHIALEGRCF
                     VIGCNQYVEKNMYPTDLNYYKELDAEPEIMCPGGSCIVDPFGKYVAGPIFNKEEMLIA
                     DLDLEKIVLSRLDFDSEGHYSRPDVFELIVHE"
     gene            18208..19812
                     /locus_tag="KOU88_002644"
     CDS             18208..19812
                     /locus_tag="KOU88_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3212513.1"
                     /translation="MKAKIYYNGNIITMEDSICGDAILIKDKIIKKIGTKEEVFALKN
                     KDTEIIDLQGKTLMPSFIDSHSHLIAFATTLKLVPLEDATSFKDIVKKIQDFKESNNI
                     KKGDWIIGFSYDNNFLEENKHPDKSVLDSASSENPILISHASGHMGVANTLGLKQLGV
                     TNETRDPEGGHIGRVEGSEEPNGYLEENAFFNVASKIKQPSSNEIFNSIEKAQNIYLS
                     YGITTAQEGLMEENQFNILKAMANQNKLKMDVVGYVNLKKSKSVADNNREFIKKYINR
                     FKIGGYKIFLDGSPQGKTAWLSRPYENSDDGYCGYPIYKDEEVEKFIDISLKEKMQLL
                     THCNGDAAADQLIDAFEKVLNLKEQSSENNIRPVMIHAQTVRADQIDDMKVINMIPSY
                     FVAHTYYWGDIHIKNLGEDRAFKISPLKTTIEKGLIYTLHQDTPVIAPNMLETVWCAV
                     NRITKKGIQIGENEKISPLDALKGVTINAAYQYFEEDKKGSIKEGKLANLIILDKNPL
                     TIDPMKIKDIKVLQTIREGEVLYSLK"
     gene            20628..21899
                     /gene="serS"
                     /locus_tag="KOU88_002645"
     CDS             20628..21899
                     /gene="serS"
                     /locus_tag="KOU88_002645"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBK3212514.1"
                     /translation="MLDIKRIRENLDCIKKAMERRGEKDFNLDEVVKLDDERRKILQE
                     VEVMKNELNTASKNIPNLIKEGKDVENEKIKLKELSDKIKVIDQNLKEVEDKMEYLLM
                     RIPNVPHPEVPQGETDEDNVEVRTWGKTTTFDFESKAHWEIGTELGILDFETASKITG
                     SRFTLYKGLGARLERALLNFYLDTNTKVNGYTEVIPPFMANRNSFLGTGQLPKFEEDM
                     FKIEGLDYFMIPTSEVPLTNIHANEILKFEQLPINYTAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVEMVKIVAPEESYNELEKLTNNAETMLQLLNLPYRVVKICTGDLGFTASFK
                     YDVEVWMPSYNRYVEISSCSNCEDFQARRAGIRFKRDKDSKAEYVHTLNGSGLAIGRS
                     VAAILENYQQEDGSVVVPEVLRPYMGVSVIK"
     gene            22223..23728
                     /locus_tag="KOU88_002646"
     CDS             22223..23728
                     /locus_tag="KOU88_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBK3212515.1"
                     /translation="MKIQNTEWGYIEWKHTYDENNPKQAMNIYIAVTMPGKKHFNHVH
                     YGQEQMIYILEGEGLYIINGVWKPFYQGMIFYIESGSTHETINTGDREIKELIVSNNV
                     DDVGESEVIDINPNNYLKKTLINYSESTLNLYAAVESIRGQFIDPFKIPLIIYDDSWN
                     IVLKNPYFPLFCFEKCNPMKFPQNCDCMNQKSSNQFVCEYGITIYNIPILYKSNSIGV
                     IRGGYVLLSDLNLDTEHNNLYDIPEGAARSIKRLLKQISKNIINFCSFNDIRKDLQEK
                     EKTIARTYHYGEQLEMNLKVAQDMVTNLRINHHFLFNTLNSMASIALDDGSYDLYSAI
                     IDLSRMFRYTMRSDLRFVELESEILYIKNYLNLQKLRYGDALKVKYLIPEKLYNLSVP
                     FNFIQPIVENAFTHGFRDIDTEKRIEIIARLDSQYAIIEIHNNGTILDGNNIDKIKAG
                     IRSNNGHGLSLIYTKFTSAYGNNFDMDIKSSDNEGTYIMIKIPIENYKEYV"
     gene            23842..24540
                     /locus_tag="KOU88_002647"
     CDS             23842..24540
                     /locus_tag="KOU88_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK3212516.1"
                     /translation="MRRALIIDDEEAVLKIITHFIEMKDMPIKIVGKATSGDEAVDKI
                     IGLEPDIVFIDIQMPIYNGLEVIEKTSHLSKKINFVVITAFNYFEYAQKALRLNVKDI
                     LLKPLDMKEFTKSVEKIIGYQYTNNDLLNEILEYINLNYSNDLKLNDCARLFLTNPSN
                     ISRIFKSNLNTTFISYLNHIRIEKSIELLENTTKSINEIAEIVGYNSLNNFYKNFKIE
                     KGMTPKVYKLNTKN"
     gene            24825..25913
                     /locus_tag="KOU88_002648"
     CDS             24825..25913
                     /locus_tag="KOU88_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212517.1"
                     /translation="MSDKVNMKNIICIAGAYLATAIGSGFATGQEILQFFASQGYMGL
                     IGALISMVLFSFLGAEVITRGRELKLKEPTRIYTFYCGKILGKFYEWFSPIFLFGILI
                     VMISGAGSTLTEYYGINPYLGRVLMAVATLITVSMGLEKLVSILGRIGPVIAVFTIAV
                     GLISLFKHFDGLSMVGEAMKNIEVTKASESPIVSGVIYNTLNIIVMIVFLTGMGASIE
                     SKKDAFWGGLLGGIVFMTAGIVMYLAMISDIGNLYMKEIPSLYLADNISPIVGVCFSV
                     ALILGIYTTAVPLLWSVTNRIVEDEHPKFKLVTTVIAILACIGGFLPFGKLVNILYPY
                     TGYMGLLILVCMVYKAITCRKKSTQSQE"
     gene            26152..27342
                     /locus_tag="KOU88_002649"
     CDS             26152..27342
                     /locus_tag="KOU88_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3212518.1"
                     /translation="MHELILISEKYKEDILDFFTDIHMHPELSFKEFRTTKAIKDLLV
                     SLDIEILDLGMETGVVGLLKGKYDGPTVALRGDIDALPIYEEVDIKYKSRYDGIMHAC
                     GHDIHTSCLVGCAYVLSHIRDSLHGNVKFIFQPAEEVNKGAKMLVERGVMENPKVDAI
                     FGLHNHPDIPCGKIGVKLGGLMAAVDTIKIEVNGFGGHGGIPNRTIDPIVASSAIIMG
                     IQTIVSRNISPLESAVISIGTINGGTANNVISEKVDMTGTCRSFSNEVRKKISENLEN
                     IVCEIARGYQATAKLDYLFDLPAVINSKEMYAIACKSVCDLYSEDAIVDPIPSTGGED
                     FSIFMEKAPGFFYWLGVGNKEQDCIYQWHNPKFKADKNSILVGTNVLCQSVINYMDKL
                     KNKI"
     gene            27433..28935
                     /locus_tag="KOU88_002650"
     CDS             27433..28935
                     /locus_tag="KOU88_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HBK3212519.1"
                     /translation="MRALNVVERAGNKLPDPVTIFLLLCIIVVILSAVISNLGVEEIH
                     PSTKEVVKVVNLLEKEQIQSYLGSIVTNFQSFAPLGLVLVTMLGAGVAEKSGFMEVLM
                     KKGISKVPQKLVTVAIVFAGMLSHTAADVGFIILPPLAALVFLGIGRHPLVGMFAAFA
                     GVAGGFAANVMLSTTDVLLAGFTIPAAQMMDPSYQGNPAMNLYFAFISAIVLTFAGAF
                     VTEKFIAPRFTKYNDSTNDKDIQELSELENKGIKYALLSLLVVVVVIVALCIGDNAFM
                     KDPETGSILSSNAPLMKGIVPIITIIFLTPGLVYGKVSKKIKSDKDLVSMMGSSMSDM
                     GGYIVLAFIASQFINLFNLSNLGTILSITGAKLLAESGIPSYGLIIGFILLSGFINLF
                     VGSASAKWAILAPIFVPMFMLLDFNPALTQIAYRIGDASTNPISPLFPYFPVILAFAR
                     RYDKDIGIGTVISNMIPYSVVFTLIEIIILLLFMGIGIPLGPGGGISYVL"
     gene            29007..30263
                     /locus_tag="KOU88_002651"
     CDS             29007..30263
                     /locus_tag="KOU88_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBK3212520.1"
                     /translation="MLKTTKISDPELYKIVADELVRQEHNIEMIASESTAPTEVLELS
                     GCVFTNKTEEGYPGARFQAGSEEADKLETLAIKRAKEVFGAEHVNVQPYSGSTANYCV
                     YSSILKPNDTVLSMRLDQGGHLTHGSAVNFLHDIYKYEFYGVDPNTGRIDYDALEAKA
                     KECRPKLIIAGASSYPRLIDYERISKVAKEVGAYFMVDMAHVAGLVAAKVIPSPVPYA
                     DFVSSSTTKTFCGPRSGIVLCKAEHAKKLDKGVFPGTLGSIHLNTVAAKAFSLLYLST
                     DKFKKIMEQVVVNAQTLASELISHGFSIVSGGTDNHIVMVDLRSKNLTGKQFEKALEY
                     VGITVNKNVIPDDPQSPFVTSGIRIGLTSISQRGLKEKEVIQIAGIMNKVAENIDNKE
                     VLDECKAEAQELISKFPLYPEGYFED"
     gene            30435..33209
                     /locus_tag="KOU88_002652"
     CDS             30435..33209
                     /locus_tag="KOU88_002652"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBK3212521.1"
                     /translation="MRYYNKPTKEVLKYLKTNPEIGLDDNEVEERKLRYGLNEFTIKE
                     GRTFWDELGESLTEPMILILIGAAVISSFVGELHDALGILGAIFIGISIGIITEGKSK
                     KAAHALSKLTENIEVKVLRNGKIIKISKNDLVPGDIVYIETGDMIPADGRLIQSINLK
                     LREDMLTGESDDVAKNADAVLDMEVVYSKTEIIEQDAIPAKQVNMVFGGTLVAYGRGI
                     MVVTHTGDKTEMGKIAQNLSNEDQQTPLQIKLGKLGAKIAGISGIIATLLCMFMIIQM
                     QRKGMLILDTSSILSFLQSLEPAKNAYMVCIALIVATVPEGLPTMINITLAITMQKMA
                     KINALVTKKEACETIGSVSVICSDKTGTLTQNKMMVEVAYVDGKYISGGEYQSNSYFE
                     QNCIVNSTADIEKEDNSFKYIGSATECALLLYHNDKNYNEMRKQTYLISQIPFSSEEK
                     KMSTLIRQEDSDILLSKGAPEVLLKKCSYVQQGKNIVPITPKVEKSILDEIKKLQIKS
                     MRTLGFAYKKMSNSKTEVAMTSEGELNLIGNSRSYMKEDNLVFSGFVGIVDPLREGVK
                     DSIDKAFNAGVDVKMLTGDNINTATAIGNELGLLNDGKKAVEATYIDVLTDKELREEI
                     KGISIVARSKPDTKMRIVSALQKSGEVVAVTGDGINDAPALSQADVGIAMGISGTEVS
                     KNAADIILTDDSFSTIVEGIKWGRGIYENFQRFIQFQLTVNIVAFIIAIISQLTGKDM
                     PFTTIQLLWVNIIMDGPPALALGLEPVRDYVLKRKPINRHSGIIARSMFVNIIINAIL
                     IITIVFTQSAFNILGATSEEQGTVIFSLFAFSALFNALNCREFGLNSTIPNFFKNKLA
                     LQIIVVTGIIQIIFTQVFQSFFNSVSLDFDMWIKIILFASTILLSNEFVKLILRTMKN
                     SRTMNFNSKN"
     gene            complement(33274..33459)
                     /locus_tag="KOU88_002653"
     CDS             complement(33274..33459)
                     /locus_tag="KOU88_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBK3212522.1"
                     /translation="MFFISDIYIKSPIKFDTPLQKEAYKILQKLDIDFECVDTDEAIT
                     MEDCVQINKKLNMKMVI"
     gene            33834..35012
                     /locus_tag="KOU88_002654"
     CDS             33834..35012
                     /locus_tag="KOU88_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBK3212523.1"
                     /translation="MFSKILVKTFIRDSENVQNTDVRNKYGYVAGVVGILSNLLLFVI
                     KVFIGMLTSSIAIMADAFNNLSDMASSAITMIGFKLASKPADKEHPFGHGRIEYLSAL
                     IVAFMVMLVGLQFVKSSIERIVNPIPVKFEVIPLILLIASIMIKIWLSRFNKFMGNKI
                     DSSALKAVSLDALGDVFTSSCVVISFIVARFTNFPIDGYVGIVVSLVILYAGFSLVKD
                     TINPLLGEAPDEEMVNSIIELLLSYKYIIGTHDLIIHNYGVGRCIASIHAEIPSNIDI
                     MEIHEIIDTAEREISEKLDIYLVIHMDPICLEDKEVMSAKKELEEILKKNSLVKSMHD
                     FRIVGKGSKKNLIFDIVVNPSEFSKNMSEDDLKEDITKLVKEINPEYNCVIVVDKDFI
                     "
     regulatory      35139..35224
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01786"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01786"
     gene            35342..38260
                     /locus_tag="KOU88_002655"
     CDS             35342..38260
                     /locus_tag="KOU88_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021362860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SrtB-anchored collagen-binding adhesin"
                     /protein_id="HBK3212524.1"
                     /translation="MKKGNRKALLISLIMILSMVVSTIYPTVSYASELGENSQIQSGS
                     TNSSTGEEKESDNKKPEQTPEKDKATDNKKPEQTPEEEKPTDNKKPEQTPEEDKSTDN
                     KKPEQTPEGEKPIDNKKPEQIQEEDKSTDNKKSEQALEDEKPLDNKNTEKTPEEDNLL
                     EDENLLKVLEEELNEENEDYGFVVKINNNTIETESMKKISFNLTYTPTSKGIQAGDSI
                     TFKVPDVFNKVNLDYTSECFDKTESNGEYTLTFRELPNGQSVMQGKIGLEAYVKKVDE
                     DTNAKIHIETTGKIESGSGDIDVEIKPGDKTDVPDAKGILKKLVEGKKSTTVFMPVKN
                     KDINYSIQVNEKQEELKDIILYDELPEGLTLINGSVSVVTSDGKEVSDFNIEQSKNSI
                     SVNFGNIDKSYTVKYKARISDKNAKHGNKYKNVARIESDGKKIQEDDATVSIFDRGDD
                     YLLTKGHSGATNITQVGQVINYQISINDDKSPISNVVITDNIPEGMRLTTSGEAGHDF
                     RVVEIPMNGSWTPWSKEKIANNISYEVEEKRNESGQVDKVITGFTINLSKEEVESKFF
                     IAYTLKVISIEDSYINRAVLDANNSEIDKNDEINFKKNSGLISAKKEVDKKVLNSSDN
                     QIVKYKINMSTYGVYDAGQVNLLDEVNSVLEISNIKYSDNLELKKEAGDGKNTIRLVN
                     KYEFKQIKEGEPVQSWVTFDANFTNVKVGETIRNVAQINGSSPPGVETTKQGYAFEAK
                     KVDALDKNVLSGAKFNLEDAFGNIVVKDLVSDEDGIIQSSVKNPGTYYLVEIMAPRGY
                     EKLKDKVKVEIGNEDIGKIVDIGNIENIRQENPPVNPPAPPNTDEPMVNPPVPPSTDK
                     PRKPSSSSDTEDTIVINPPVPPSEDIINPPIPEVLNPPVPPSEEMIETPVKQIIPIPE
                     VVKPSVSEEKNNRVKDDTLVNPPVPPKTGDSTTIIGEILLVIGAIVGLIVLRRNKNTN
                     "
     regulatory      38445..38530
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            38630..39292
                     /gene="zmp1"
                     /locus_tag="KOU88_002656"
     CDS             38630..39292
                     /gene="zmp1"
                     /locus_tag="KOU88_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease Zmp1"
                     /protein_id="HBK3212525.1"
                     /translation="MRPSKKLLIAIISIFLISSVPVSAHADSTTIQQNKDTLSQIVVF
                     PTGNYDKNEANAMVNRLANIDGKYLNALKQNNLKIKLLSGKLTDEKEYAYLKGVVPKG
                     WEGTGKTWDDVPGLGGSTVALRIGFSNKGKGHDAINLELHETAHAIDHIVLNDISKSA
                     QFKQIFAKEGRSLGNVNYLGVYPEEFFAESFAYYYLNQDTNSKLKSACPQTYSFLQNL
                     AK"
     gene            complement(39411..40373)
                     /locus_tag="KOU88_002657"
     CDS             complement(39411..40373)
                     /locus_tag="KOU88_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBK3212526.1"
                     /translation="MKKGYVYIILTTLFFSSMEISLKTVTNDFNPLQITLSRFFVGGL
                     VLLPFAVKRLRALSLSITKSDLKYFAFLGFMCVVVSMSLYQLAVLNTKASVVAVLFSC
                     NPVFVMLLAYLILKEKIYRHNVISLILEVLGIIVIINPLHTKLTLSGIFLTLSSAIIF
                     SMYTVFGKRKTLKFGGIVVTCFSFIFGSLEMLILVLLTKINFIADILNKNKLHVFANI
                     PIFSGYTLHNMPIMIYVFVFVTGVGYALYFMAMEATSTSLTSLVFFFKPVISPILALL
                     ILKEIIPINMVIGILLIVIGSIISIIPTIITQMHNKHVEALYKE"
     gene            complement(40543..>41650)
                     /locus_tag="KOU88_002658"
     CDS             complement(40543..>41650)
                     /locus_tag="KOU88_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3212527.1"
                     /translation="IYGEENVFDFSIGNPSVEPPETIKAVINDILNEESPNLVHGYMN
                     NSGYEDVRDAIAEHINKKDGLNLTRENLIMTCGAAGGLNIILKTLLNPGDEVIAFAPY
                     FGEYKNYTENYDGKLIEVPTNIETFEPDLDALKNAITPKTRALIINTPNNPTGVIYSE
                     ELLKNLGELLDSKQKEFNTSIYLISDEPYREIIYDGAKVPCVLKYYRNSFIGYSYSKS
                     LSLPGERIGYIVANGQMDDFDDVMSSLNVANRILGFVNAPSLFQRVIARSLDAEVDVN
                     IYKKNFDLLYNSLIDMGYSCVKPNGTFYLFPKAPIEDDKKFCNDAKQFNLLLVPGSSF
                     GCPGHFRVSYCVSYDKVKSSLPAFEKLAKLYNLK"
BASE COUNT        16470 a         4549 c         7177 g        13454 t
ORIGIN      
        1 agtaggatat attaataaat atgatagaat atatattata aattaaattt attaatataa
       61 ggggggaact ttgagttctt atagatttct tacattataa gaacctatac tttatgcggg
      121 agttattaaa agtaacactt atagtaatgc ttgttttgat aaatgctttt tttgtagctt
      181 gtgaatttgc tatggtaaaa cttcgtagtt ctaggattga taccatgata actgaaggta
      241 ataataatgc aaaaagatgt aaaataataa aagacaactt aaattcctat ctttctgcat
      301 gtcaacttgg tataacactt tgttcacttg cattaggttg gatgggagaa tctacagtta
      361 aagagttaat tttaccaata gtaagtgtat ttaatcttag tgaaagtatt atatatacta
      421 tatcaatttc catttctttt ttaattataa caatgatgga ggttgtaata ggagagttgg
      481 ttcctaaagc tttagcactt tataatacag aaaaaataat gttgagtaca tcttttttat
      541 tagtaggatt ttataagtta acatatccaa taatatattt tttcaactta agtactgatt
      601 tatttcttaa accatttgga tattcacaag ctgatgaggt tgatgaaccc catacaggtg
      661 acgaaataag actattagta gaagaaagtt ataaaagtgg acttatagat gaatcagagc
      721 aaagattagt tgataatatt tttgaatttg aagaaaagaa aattagagag ataatggttc
      781 ctagaactga tatggtatgt atatatgaaa gtgattctga agaaaagata ttagctattt
      841 taaaagagga aggtgttaca agatatccag tatgcagaaa aaataaagat gatatattag
      901 gttttgtaca tataagagat ttatacaatc aaaagataaa tgaaaataaa attgaactag
      961 aagaaatatt gagagatatt atatatatat ctgaaaattt aactatagat aaagctcttg
     1021 agagaataag aaaggaaaaa cttcaacttg ctatagttgt ggatgaatat ggtggtacat
     1081 ctggtgtggt aacaatagaa gatatactag aagagatagt tggagaaatt caagatgaat
     1141 ttgacaaaga agagactcat attaagaaaa taggagcagg ttcttactta gttgatggaa
     1201 ctgaatctat caactatatt aataagtatt ttggacttga tatagagcat gatggatttg
     1261 acagtatagg tgggtggata tcctatatgc ttggttcaaa tattaaagta aaccaaagtg
     1321 taacttttga aaattacaat tttacaatat tagaattgga taaattgagg gttgtaaaac
     1381 taatcataaa aagtgtaata taattatatc aaaaaatatt ggaggaattg tatgcaaaaa
     1441 gtagaaggaa ttatttttga catggatgga gttttgtttg actcagagag aatttctctt
     1501 gaattttgga tggagacgtt tgaaaagtat ggatatacta tgactaagga aatttataca
     1561 tcagttatgg gaagaaatcg taaaggaata atagaaggtc ttacagagat atatgatagt
     1621 tctgtaccaa taatagattt atatgacgaa aaaactaaaa acatgattga atttatggag
     1681 aggaagggag ctcctatcaa attaggagtc aatgaactaa tctctttttt aaaagaaaat
     1741 ggatacaaaa tggctgttgc aacatcaaca aagagagaaa gagcagtaaa gagattagct
     1801 aaggcaaatt taaaagatta ctttgatgct atagtttgtg gagatgatgt tgtaaactct
     1861 aaaccaaacc ctgagatatt cctaaaagca gctaaaaaga taaatgttaa tcccaaaaat
     1921 tgtattgtca tagaggattc gcctatggga gtcgaagctg catacaatgg tggtataaga
     1981 tgtataaatg taccagattt aaaagagcca gatgagcaaa ttaaatcaca atcacataag
     2041 atacttgaaa ctttactgga agttagagaa tacctaaaaa gtttgaactc taaagaatgt
     2101 cacaatctat aatataaagt attaattaaa taaattaaat ataatttctt tgatttagaa
     2161 taaatccatg aatatgagaa aaaataagta taaacagcta ggaggaatat tcatggataa
     2221 tgtaggttct ctattatatt ttttatttaa ttttttcttg tatggtttta taggttggat
     2281 aattgaaaac ttatatagtt attataaaca agggcatttt caagaagatg gatttttaaa
     2341 tggtccattt aaaccaatgt atgcaattgc aatgtcgatt ataatagagg tctcaagatt
     2401 tattgacccc aataatatat ttgcattgct tttattatgt ctagtagtgc cgacagtagt
     2461 agaatatatt acaggaatac ttatgaaagt atattttaat aaggtctatt gggattattc
     2521 agattataag tacaatagta gaggaatagt atgtctaaag ttttctgtat attggactat
     2581 attgacattt attggagtta gatattttca agtgtatata gttgatagtt tatatagtct
     2641 tataatacct tattggccaa ttgttgtaac tatactttta gtaacattgt ttgtggatga
     2701 aattcttact ataaaatttt tgaggggaaa taaagatata gtagaaagat aactttaaaa
     2761 atataagttg aatttagatt gtagttaaaa gaaagctatg ttaaaatggt gaaatcattt
     2821 aaaattagct ttctttttta tttgataaaa ttattttata atatatctat aagttgtaaa
     2881 gttttttatt aaaattaaaa taaagtgtag aaaatgggga gtgatttatg atgggtaaaa
     2941 taagatttgg tattgttggg acaagcaata tagcaaatat atttctaaga gctgcatcta
     3001 gggttaaaga ctttgaattg gttgctgtat attctagaaa tttagaaaaa gctagagaat
     3061 ttggaactct atatggagca agtatttttt ttgatgattt agaacaaatg gctaaatcga
     3121 aggatataga tgctgtatac atagcttctc caaatgcatt acattcaaag caaaccatta
     3181 cttgtttaaa acacaaaaaa catgtgcttt gtgaaaagtc gttagcatct aatttaaaag
     3241 aagtcaaatc aatgataaaa acagccaaag ataataatgt attgcttatg gaagctatga
     3301 gaattacatg tgttccaaac tttaaagcag ttaaagaaaa cttgtataaa atagggaaaa
     3361 taagaagatt ttttggaagc tattgtcagt attcttcaag atatgataaa tataaaaatg
     3421 gaattataga aaatgccttt aaaaaagagt tgtcaaatgg agctttaatg gatataggag
     3481 tgtattgtat acatcctatg gtgaatttat ttggtgctcc aaaaactgta aaggcagttt
     3541 ctcatatact tcaaactgga gtggatggag aaggttcagc tgtatttcaa tatgatgata
     3601 tggatgcgat aattcagtat tctaaagtag ctgattctta tataccatct gaaatacagg
     3661 gagaagaggg aagtataata attgaaaagc ttaatctatt tgaaaaagct attattaaat
     3721 acagagatgg aagagaagaa gatatatcta ttccaaaaga aaaagcagag gaaaagccta
     3781 gagaaataga aggaatgtat tatgaacttg tagagtttat aagtcttata aataacaata
     3841 aaatagaatc aaatataaat tctcatgaaa attcaataat agtaatggaa attatggatg
     3901 agataagaag acaaagtagt attgtttatc cagctgatag tatatagttt atattagaaa
     3961 atataagaat ttataatata tattcttaaa taaatttaat tttaagttaa ggtaaggtgt
     4021 atacttaacc aagtgttaaa atgtcaaatt ataagtatga aaaagtgcta aaaagaaatt
     4081 tatttttggc gtttttttct ttttttttac aattttgtaa cagtatcaaa aaaagttttg
     4141 acgattttat tacaattttg tagttgaata tacatatcaa aactaatatg attaataata
     4201 acataaattt gaatattttt agaggagaga aaatatgaga aaattgatat actttattac
     4261 accttttata ataggcgtag tatttttatt tgggttagac aaatttcttg attctaaaac
     4321 tgatgaactt ttgagggaga aaaatctact tccaattatg gatgatactt taagtgatat
     4381 aaaagataaa ggggttacag caaataatca ttttttaaga gaaaaggata ttatgatttt
     4441 ggggtcatca gaacttagta attcaacaaa acaacatcca aagtactatt ttaatacaaa
     4501 taggagtaaa aataaggtgt ttgcaattgg gagagcctat actcagacat tacaagatgc
     4561 tgcaatatta ggaagtatga atcctaatat tgataataag aaagttgtct tgttaatttc
     4621 tatgcaatgg tttatggaaa aagacggagt cacaagtcac cattatcagt ctagattttc
     4681 accaatacaa ttttatcgat ttttagataa tccaaaaata tctaaacaaa ataagattga
     4741 atatgcaaaa aaatcaagta agttattatg gggaagtgac gagtataaag cagaagcatt
     4801 atatgctaag ctatatgagc ctaagacatt tcctgaaaaa gctgaaaagg tgcttttaga
     4861 gccttatttt caaggaagaa agtattgtat agctcttaaa gaaaagggta ttctttataa
     4921 acgattaatt aagctagata aaaagagagc aacaaaaaga aaaagaccaa taaattggtc
     4981 atatgagaga aagaaagcca ttgaagatgc taaaaaaaga gttggtaaaa atccactaaa
     5041 tattgataag tactattata aagagcattt taaagatggt atagagcaat acaaaggaag
     5101 agacaaagat gtaaatttat taacatctaa ggagtttgaa aattataaac tgatgctaaa
     5161 tgtatgtact gacttaggta ttaagccagt tgttgtatta atcccaagta tggataaatt
     5221 ctataatttg actggtattt ctgaaaaaga aagaaatcag tactacgata aagcacaaaa
     5281 aatagcagaa agcaaaggct ttgaagttct aaaccttaaa gataaagggt cagataagta
     5341 ttatttaagg gatgtaatgc atcttggtac gaaaggatgg gtagatgtct gtgagagatt
     5401 atttaaaata tttaaagaac aataaagatt tgttaactag tatttgttta actatggtta
     5461 taatattggc gataggagtt ctaacattta ctccatttaa agaattgcca tttatttata
     5521 acggatttta aaggagcatt cttatatgaa aattattgaa ggaataaaaa aatattcaaa
     5581 tacagataga acagcactaa tgtgtaatgg agataaactt tcttataaag atttaaatga
     5641 atattcagat gctatatcag tatttctaaa ggatgtatac aaagaagaag atactcctat
     5701 agtaatttat ggaaataaag aaaacatgat aatggcatgt atgataggag ctttaaaatc
     5761 aggtagagcg tatgtgcctc ttgatattag ttttccaatt gatagagttt ttgaagtcac
     5821 taaagagata aaaccaaagg tattatttaa ctttagtgat gaaagaaatt ttggagatat
     5881 caatgtaatt gatatggata aattaaatta tataataaat gaatatcagg gaaaatcatt
     5941 agataaagaa aactgggtaa aagatgatga aaatgcatat atactattta cttcaggaag
     6001 tacaggaaag ccaaaagggg ttcaaataag ttcaaacaat ttagatagct tttcagattg
     6061 gataagccca tatctaaaca tagatggaag tgaaaaagta ataatgaacc aaccagcata
     6121 ttcttttgac ctttcagtta caacaatata ccctggtctt atccatggag ctacattatt
     6181 ttcaatatca aaagatgtat tagcagacta taaagaacta tttagacaat ttagtatctc
     6241 agatatagct gtatgggtgt caactccttc ttttgcagga gtatgtataa ctgaaaaaga
     6301 gtttaatagt aaaatgcttc ctaaccttga gtcaatgata ttcataggag aagcactttc
     6361 aaaaaatctt actaaagaac ttatgagtag atttccaaac acaagaatta tcaatggata
     6421 tggaccaacc gaggctactg ttggtgtaag tgtaaatgat atgactcaaa aggctataga
     6481 tgatgaaaaa agtcttccag ttggataccc tatgtcaaat tgtaaaataa aaatacttga
     6541 tgaagatgga aatgagctta aagaaaatga aaagggtgaa attataataa ttggaccatc
     6601 agtttctaaa ggttacttca ataataaaga aaagactgat gaagtatttt tctatgatga
     6661 aatagatggt gtaaagtgga gagcttataa aactggagat atgggatatc ttttagatgg
     6721 aaatatatat tattgtggaa gaaaagattt tcagattaaa ttaaatggat ttagaattga
     6781 aatagaagac atagaaaata atttgagaaa agtacataat gtaaaaaatg cagtagtttt
     6841 accagtatat aaggacgaaa aaattgctta cttaaaaggt attgttgagt taaatgaaaa
     6901 gaatgattta agtaatatta aaaatgggat gataataaaa aaggaacttg gaaagtatat
     6961 accttcatat atgattccaa gaaatatttc aataatctct gagtttccaa caaatatcaa
     7021 tggtaaaata gacagaaaga aacttatgga ggaaatttaa tgattttttc acaatatgga
     7081 gattattttt atctttatat attattatta acatcaatac cagcagtaat tttaggtcta
     7141 atgggcaaga atataaagta ttatggtatg ttggcaagtt tgtttatgat attcttaata
     7201 gtaggaattg atgtccaact aaagtacttg gtaatattta ttattcttga agtaataata
     7261 gttaaaggat atgaatatgt aagaagaaaa actaaaaata aatacatata ttggggattc
     7321 ttgtttgcat caatgctccc aataataata aataaaatat ctccagttac ttcttttgga
     7381 ataattggat ttattggaat atcatactta aatttcagaa ctatacaaat ggttattgaa
     7441 atttatgatg gagctataaa agaagttaaa atttcaaaga tgctttattt tatgttattt
     7501 tttccaactt taagttctgg acctattgat aggtcaagaa gatttgaaca ggacttggaa
     7561 aaacaaatct ctagaaaaga gtatatagaa gaatacttac tgccaggaat aaaaaatatt
     7621 gtcatgggag taggttataa gtttgttata gcatttttga taaatacata ttgggtatca
     7681 agaataccta aagatatgag ttttataaat attttaagtt atatgtacgc atatagttta
     7741 tacctgttct ttgattttgc aggatatagt ttatttgcta taggtacagg gtacatattt
     7801 ggaatacaag tacctataaa ctttgacaag ccatttatca gcaaagatat gaaagagttc
     7861 tggacaagat ggcatataag tctttcaaga tggtttggag attatatttt ttctagattt
     7921 gttatgtcat caatgagaaa gaaaagattt aagaaaagga ctactgctgc tcatgtggct
     7981 cagatgataa ccatgataac aatgggattt tggcatggtc taacttggta ttatgttgct
     8041 tatggtgtat accaaggatt ggcacttgtg ttaactgata tatatcagcg aaaatctaaa
     8101 ttttataaaa aacataaaaa agataaatgg ttcgagagag tgcagatttt cattacattc
     8161 catattgtgt gttttggatt gctgatattc tcaggttatt tagcttaatt ttaaggagga
     8221 aaatttatgc aagaaacagt tatagaaata tttgaagatg tattagggac tgatgagata
     8281 agagaagatt tagaccttaa tttatttgag acggaacttt tagactcatt agctataatt
     8341 gaagttttac ttgaaattga aaatagatta gggatagagc ttcaaccaac tgatttagag
     8401 agaaaagata tgtctactgt aaataattta gtaaaattct tggagacaag aaaataaatt
     8461 agtagttaga ctttaaatat taatttataa aataaaattt tacaaagtcc atctgatact
     8521 aatatttgat ggactttttt aatgataata caaagtcttt tgaaaataac tttaattaag
     8581 taaaaaattt aatacataaa tatgatttca taaatcttag gtatcattgt aatattatag
     8641 gagaaaaata tattatattt aggaggaaaa tgaatgtctt taaattcgat agatagaaaa
     8701 aaagaaatac ttaaattact agattcaaaa gggaaggtaa acactaaaga attagtaaaa
     8761 agattagaag tatcatcaga aacaataaga agatatttgg aagaattaga aaatgaaaat
     8821 aaattaaaaa aggtatatgg tggtgctata aaaataaatt atggagtgat tgaaccagaa
     8881 catataaaga gaaacaatac taacctagat aaaaagcaaa gtattgctaa atatgcagct
     8941 aagtttgtaa atgacaatga gtcaattatc atagatgaag gtactaccaa tttgcagatt
     9001 gtagattata taatatctgt aaacaattta aaaattatta caaactctta tccagttctg
     9061 tcaaaattga tttcttacga gaatcaaggt ttgtttgatg gagaagttat atttattggt
     9121 ggaaaagtaa atttaaaaca ccaaaggaca gcatgtccaa tatcaataga tgctatgaaa
     9181 aacttatacg tagataaagc ttttatatct agtgaaggta tacttgatag ttttggaatt
     9241 agtagtatag accaaaataa ggcattgttg tcaaaagcat atataaaaaa ttcaaaggaa
     9301 agttttgtat tatgtgatag ttctaaaata ggaattgcta gtatgtataa gatagcagat
     9361 ttagaggaat tagattttgt tatttgtgat gtagaacctc cgaatgaatg gaaggataag
     9421 ttaaatgaga taaatataac atggatagaa gcaaaataaa cccttagttt tatataatac
     9481 aactatgctc aatacaacta aattcataaa atatagtcag ttcatagatt aagattagaa
     9541 agtaaatttt agattgtaac ttaggatttt atgggaatat gatacaaaat aaaaacaact
     9601 aaatacaact aaaaacagaa atttaatata tatttaacct aaatatgatg tataattaac
     9661 atatgaaagt tatactttaa aagtaaaaac aattaaaaac acaaaaattc taaaaagaat
     9721 ctatggaggc tataaatatg aaaaagatat atggagaaaa aataaaagca gtagtattcg
     9781 attgggctgg aacaacagta gattatggat gttttgcacc tcttaatgta tttatagaga
     9841 tatttaaaag aagaggtata gatgtaacaa tggaagaagc aagaaaacct atgggaaaat
     9901 taaaaataga ccatataaga gaaatgtgtg aaatggatag aataaagaat atttggtcag
     9961 ataagtttgg taaagtgcca actgaagatg atgtaaatga actttatgct gaatttgagc
    10021 caatgttatt tgagacatta gaagagtata cgactccaat tcctcatgtt gttgaaacta
    10081 ttgaaaagtt gagaaaaaat ggattaaaaa taggttctac aacgggttat acaagagaga
    10141 tgatgaacat agttgaacca aatgcagcaa agaaaggata ctcacccgat tttcttgtaa
    10201 caccatcaga agtatctcaa ggaagaccat atccttggat gtgctataaa aatgctgaag
    10261 ctttaggggt gtctcctatg agttctatgg taaaagtagg agatacaata agtgatgtaa
    10321 aagaaggcgt aaatgcagga atgtggagtg ttgctgtaat aaaaggttca agtgagttag
    10381 ggcttacaca agaagaagta gagaacatgg ataaggaaga attaaaagct aagatgagta
    10441 tagtttcaaa gaaatttaaa gaggcaggag cacattttgt aatagaaact atggctgagt
    10501 tagaagatat actaataaaa atagagaatg aaactattaa atcagatttt gtaccagaaa
    10561 atgattacat attacttaca ccaggaccac tatctactac taaatcagta agagcatcta
    10621 tgttaaaaga ttggtgtact tgggatgttg aatataataa cctagtacaa gatgttagaa
    10681 gaagattagt atctctagca acccaaaata cagataaata cacaagtgta ttaatgcaag
    10741 gaagtgggac tttttcagta gaagctataa taggaagtac tatttcaaaa gatggtaaac
    10801 ttcttgtaat tgcaaatgga gcatatggaa agagaatgaa agatatatgt aattatctta
    10861 acatagaatt tgttgattgc acatttaaag atatagaagc agtggattta aatgtagtag
    10921 aaaatttatt aaaagaaaac aaggatataa cacatatatc aatggttcac tgtgaaacta
    10981 ctacaggtag attaaatcct atacaagagg tagggaaact tgcaaaagaa tataacaaaa
    11041 tttatatagt tgatgctatg agtagttttg ggggaattga gattgatgtt gaagatttta
    11101 atatagattt tttagttagt agttctaaca aatgtataca aggagtacct ggatttggtt
    11161 ttataatagc taataaagag aaattatcta aatgtaaagg tatagctaaa tcattatctc
    11221 ttgatgtgta tgtgcaatgg gagactatgg agaaaaataa tggtaaatgg agatttacct
    11281 cacctacaca tgttgtaaga gctttttatc aagctttatt agaattggaa gaagaaggtt
    11341 ctgttgaaaa aagatatgct agatataaag aaaatcagtt tacaatagct tcaagattaa
    11401 aatctttagg atttgatact ttggtgaatg ataatgctca atcacctgta ataacaactt
    11461 tcttatatcc taaaaatgca aagtttgaat ttatggaatt ttatacttat ttaaaagata
    11521 atggatttgt tatctatcca ggtaaattga ctgatataga tacatttaga ataggtagca
    11581 taggtgaagt ttatccaact gatatggaga gactagctga tgtaatagaa aaatttatca
    11641 atagatagaa gaagatagtg tcttgtaggt tacagaatag tgcggaaagc ccactccttt
    11701 aggtgtgtga gatgatagca caaacagtgt ataaaaagta ttgacagtag aatttaaaga
    11761 cttatatttt agaagtttat acaatgaata tataaagatt gagtaatagg gatatatttt
    11821 atttaaacca caatctaaga aattagattt atagtttaaa taaagaattt ccctattatt
    11881 tttatgccta tttatagaaa ataaatgata gttgctttac taagtattat tatcatactt
    11941 gacaacgtaa caatgttttg ttatattagg tttaaagata aaatacggta aagaaaggat
    12001 atcattatga atgaagaatt aagttcacta agatttgatg gtgttggaaa atgtaaaggt
    12061 ggaatttttg ataatgttaa tatatcagga acaggcaaaa tagaaggaag tgtaaaatgt
    12121 agtaaatttg attcttctgg ttcagcaaaa gtttttggga caacagaatg taatgaattt
    12181 tttacatctg gtttaagtaa agtagaagga aacatactgg catcaaaagt tgagatatcg
    12241 ggacttctta gatgtacagg aaatattaat tctgttgaaa ttgatactag tggaattatt
    12301 aatgtagaag gaagtataaa atcggatatt attcatggag aaggatattt aaaagcaaat
    12361 gagaatatag attgtgaaaa tatcaattta agtggaatct tggagtgtaa tggatttttg
    12421 aattgtgaag aagttaatat tagtttaaat ggaacttcta attttaatga agttggagca
    12481 agtagtataa atataaaaaa ggggcatgga gattattgca aaaaatttcg tatgctagaa
    12541 aaaaagcata tcaactttga aaaagtgtct tcaaatttaa taagtttagg tctattatca
    12601 attagaaagt atacagaaag taaattgttt gcaaatatta tagaagcaga tgaaataagc
    12661 ttagaaaata gtgaagtcaa agttgtaaga ggaaaaaata ttaaaatagg caagggatgt
    12721 tatgtagaaa gtttggagta cagtgaaagt atagagattg atgaagattc aatagttggt
    12781 gaaataaaga atataagtga aaaaataaaa ttaaagaagg ataagtaata aataggttta
    12841 aaaataaaat ttaaaatgag gtaataatat ggaaaaaggg tctataaaaa tacttggaga
    12901 aggctttata agtagtggtg agtatgaaaa tataaaaatc gtgggaagtt ctaaatcaaa
    12961 aggaaatgtt aaaagtaacg aagtaaaagt ccttggagat gcaaaatttg aaggtgacat
    13021 caatataaaa aattttgttg ttaacggaaa aactattata agaggcaatc ttaaagcaga
    13081 gcgtgtaaga gtgaatggtc aacttaatat agagggagat gcagaaatag atgacttagt
    13141 tataactgct caacagaaag tggatggcaa acttaaatgt aataatgtta caataagagg
    13201 acaattaagt gtaaatgaaa atatgtatgc acaagatata aaaatctatg gcgaaatgag
    13261 aaataaatca aatatagaat gtgaagatat aaaggtatat ggagtaataa aatgtgatgg
    13321 tcttttaaat ggagaaaata tatatgttta ttcaggagga ggttcttatt gtaaagagat
    13381 aggggcaact aatataaaaa taggaagaag caaagatgct ttttcattaa ttaaaatcat
    13441 taatattttt tcaggaaagt ttaaatgtaa tttgatagag ggagatacta ttgaattaga
    13501 agatgcatca ataaaagata tacgaggtaa aagcatatct ctagtagata attgtgacgt
    13561 tggaaatatt gaatacagtg ataatttatc agtttcagat aattctactg taaaaaacag
    13621 tataaaggtg ggctagaaaa gttatggaag aattaatatc taagaaagat ttattgagta
    13681 aaactaatat atcttatggt caattatata gatggaaaag aaaaaacata ataccagagg
    13741 aatggtttat aaaaaaatca gcttttacag gtcaagagac tttctttcca agagataaaa
    13801 tactagaaag aatagagtta atattgtcta tgaaagaaga gacttctctt gatgatattg
    13861 caaatatgtt tatgaaaaag gatattaata aagaatttga cattgatttt attctcagta
    13921 aagaagttat atgtaattat accaaagaaa tatttcaaaa tttatataaa aaagagcaaa
    13981 gcataggtaa aaaagaactg cttatattga gcataataga gaagttttta gttaaatcta
    14041 taataacttt tgaagagtta aaattgatag tgaatataat agaagaaaat tttacatcaa
    14101 tatacaatga aagtggaaag atttatttgt ttagaaagtt tggagttcca ttcgtagtag
    14161 gatgtttgga ttataaaaaa gtaaagtttg aaaaagatgt agttaagatt attgaggttg
    14221 acttgacaaa agaaataaat gatataagta taaagttatc atagtgtatt atcttatata
    14281 atgtattata ataatatact taaaatacac tttatttaaa tatttagttt aaagatgaga
    14341 ttttatgtga gtgtgtaaaa gttaaagata gatttaagta ggttataggg attagtaaat
    14401 aataaaatga accatgatga attactataa attgtattta aactacattt tctacttata
    14461 gtaatatcaa tggttcattt tattgttatt aagataatac agtatttata aaaatacttg
    14521 atataaatat agtaaattgt ttaaatagaa ttattgcctt aatttattca aataatgagt
    14581 ttttaaaatc taagaaatat ccttgtggat gaagacatac aggacaagct tttggagctt
    14641 ctttacctat atgtatatgg ccacaatgtg tacatatcca ttgtatatct tcatttcttc
    14701 tgaataaagt accttcttct aaatcagtag catatctacc aaatctatca ccatgaactt
    14761 tttctatttc agctatattt tcaaataact tagctataga ttcaaatcct tcttcacgtg
    14821 ctgtttttcc aaagttttta tatacatcat cccactcttg aagctcatta tgttgtgcag
    14881 ctttaaggtg ttgtgctgtc ttgtcatata aatctacagg gtatgctcct gatatactta
    14941 tattttcacc agcaaattct tttaatttag aaaagaattg ttttgcatgt gatttttctt
    15001 ggtcagcagt gtaattaaat aaagactcta ttatatataa tccttctttt tttgctacag
    15061 atgcagaaat attgtatcta tttctagctt gactctcacc tgcaaaagct cttaataaat
    15121 tttctttagt tttactatct tttaaattca tattctacct ctctatcata ataaattttt
    15181 acaatatttg attcttttta tttattattc caataggaga tataattatg ctcaatttag
    15241 tcagcatttt taaaattatc attaattttt tttaaaattc taagaaattc ttgtttttca
    15301 ttttctgtaa tattatggta tgccgtctct ttaacttgtg ttgagatgct attaaaagta
    15361 tcttctataa gcagtgcctt ttttgtaagc tttatatacg tgatacgttt gtcatttgta
    15421 catttttgtc tttctaaata tcctaggttt ataagtttat taaccaacac tgtaacagtg
    15481 gatttatctt ttcctatttt agctgcaatt tctttcattg taagtattcc attattttca
    15541 taaagtgcag ttaaaatatt tccatgagta ggtattaact cacctaaacc atttttactg
    15601 agtttatttt caatgaattt aatcatacta gcctttgttt tacttatgaa atgtacaata
    15661 tatttatctt ccataaatta ttctccaatc tttaatctat ttaaattagt ttgacataaa
    15721 actatttata aactataatt agtttaacat aaaactaaat gtattgggag gaaatttatg
    15781 aataaaaaat ttaaatcact atatattaca gaagaagaag gaaattttag aagaaatata
    15841 gttgaaagag aagtggatac attgccagaa ggcgaagttt taataaaagt aaaatattct
    15901 tctttaaatt acaaggatgc actttctgca aatggtaata agggtgttac gagaaagtat
    15961 cctcatacac caggaattga tgcatctggt atagtagaat ctagtagttg tgatgatttt
    16021 aaaattggag aagaagtttt agtaacaggt tatgacttgg gaatgaatac ttctggtggt
    16081 ttttcagaat acataagagt tccttctagt tgggtagtta aacttcctaa aaatctttca
    16141 ctaaaagaag caatggatta tggtacagca gggtttacag cagctttatc tgtgtataaa
    16201 tttatagatt ctgtagacaa gaatatggga gatgtattag tcactggtgg tactggagga
    16261 gttgctgtaa ttgcaactaa aatattgatt aaattaggtt attcagttgt agtttcaaca
    16321 ggaaaattag aagaacaaaa agaagtatta ctaaacttag gtgttaaaga tgttatacat
    16381 aggtcagaag tggatgataa ctcaggaaga cctctgctta gaccaagatg ggctggagta
    16441 atagatacag taggaggaaa tactctagca acagcaataa agacaactaa ttattgtgga
    16501 gcagtaacaa cttgtggtaa tgcaggagga gttgatttta caagttcagt atatccattt
    16561 atattaaagg gaattacttt atatggtata gattctgtgg attgcccaat gaacttaaga
    16621 ttaaaaatat gggatttatt atcaaatgaa tggaaattag atgatttaga tgatatggta
    16681 aatgtagtat cattggaaga gttaaatgat agtatagatt caataatggc aggaaaacat
    16741 gttggaagaa cagtagttga tttagaaaaa atataggtga ataaatttat aattaggatt
    16801 ataggtttta agcaaaaatg agatacttga aatttactta tgagtatctc atttttttat
    16861 gtaaaaagat ttatgtagat gtttgtgtaa aaagattatt catgaacaat taattcaaat
    16921 acatctggtc ttgaatagtg accttctgaa tcaaaatcta gtctactaag tactattttt
    16981 tctaggtcta aatcagctat tagcatttct tctttattga aaataggacc tgctacatat
    17041 tttccaaaag ggtcaactat acaacttcct cctggacaca taatttctgg ttctgcatct
    17101 agctctttat agtagttaag gtcagttgga tacatatttt tttcaacata ttgattgcat
    17161 ccaattacaa aacatcttcc ttctaaagca atatgtttca tagttgcttg ccactcttct
    17221 cttgaatctg cagtaggggc tatgtaaagt tttacaccct tagcataaag agctgttcta
    17281 gctaatggca tataattttc ccaacaaatc aacgaaccca tttttccata tggagtatca
    17341 actactgtaa gagtacttcc atctccttct ccccaaatac atctttctgt tcctgtaggt
    17401 ttaagttttc tgtgtttacc aattagctta ccttctggag agaaaaataa gtttgtgcaa
    17461 taaagggtac aatttatatc attaccatct ctttctgtta tacccattga tagatatact
    17521 cctgcttctt gtgctgcttt tcctaataaa tctgttgtag cactaggaac tggtacagaa
    17581 ttatcatagt atcttttcca atcttctcta ccttccattg ttctacttcc aacaacaaat
    17641 ccaaatgaaa gacctcttgg atatgcaggt atgaatgctt cagggaaaac tacgatattt
    17701 gccccttttc taccagcttc tttaattaat cctaatgctt tttcaacagt tttttctaaa
    17761 tccattatga ctggtgacgc ctggacaaca gcaattctta catttttatt ttccttgctc
    17821 ataaaaaacc tcctaaaaaa tatttaaatt ttttgcattg aatagattac atgagatgtt
    17881 atttgagaac taagatactt atattgtgaa taataatgta actgtatatt taaaataata
    17941 catcatgatt taaaaaatta caattgtaca gatataattg agtttagata tttaaattta
    18001 acaacttata atattttttc aattagtata aatcctatta atttgtctta tttacaatga
    18061 atagtattta cttcttggca aacaataatt aaaaataaaa cttttatatg attaaactct
    18121 aaagaaaaag tttataaaga agataatata attaagcaga aaataatgaa aaaaatttat
    18181 taaagtagac aacgtaagga gaattttatg aaagcaaaaa tttattacaa tggaaatatc
    18241 atcacaatgg aagattcaat atgtggagat gctattctta taaaagacaa aataataaaa
    18301 aagataggaa caaaagaaga agtatttgct ttgaaaaata aagatacaga aattatagat
    18361 ttacaaggta agacattgat gccatctttt atagattcac atagtcactt gatagctttt
    18421 gctactactc taaagctagt tcctttagaa gatgcaacca gttttaaaga catagtaaaa
    18481 aaaatacagg atttcaaaga gtcgaataat ataaaaaaag gagactggat aattggattt
    18541 tcatatgata ataatttttt agaagaaaat aagcatccag ataagagtgt actcgatagt
    18601 gcatcttcag aaaatccaat actaatttca catgcttctg gtcatatggg agttgcaaat
    18661 acattggggt taaaacagct tggtgttacc aatgaaacac gtgacccaga aggtggacat
    18721 ataggtagag tagaaggcag tgaagaacca aatggatatt tagaagaaaa tgcatttttt
    18781 aatgtagcat ctaaaataaa acaaccatca tcaaatgaga tttttaattc aattgaaaaa
    18841 gcacagaaca tatatctaag ctatggtatt acaacagctc aagaaggttt aatggaagaa
    18901 aatcaattta acattttaaa agcaatggca aatcaaaata aattaaaaat ggatgttgta
    18961 ggatatgtaa atttgaaaaa aagtaagtct gtagcagata ataataggga gtttataaaa
    19021 aaatatataa atagatttaa aataggaggt tataagattt tcttagatgg ttctccacaa
    19081 ggtaagacag catggttgag tagaccatat gaaaattcag atgatggtta ttgtggatat
    19141 cctatataca aagatgaaga agtagaaaag tttatagata tttcactaaa agaaaagatg
    19201 caactcttaa ctcattgtaa tggagatgca gcagcagacc agttgataga tgcgtttgag
    19261 aaagttttaa acttaaaaga gcaaagtagt gaaaataata taagaccagt tatgatacat
    19321 gctcaaacag taagagcaga ccagattgat gatatgaaag taataaatat gataccttca
    19381 tactttgtag ctcacacata ttattggggt gatattcata tcaaaaacct tggagaagat
    19441 agagcgttta agattagccc acttaaaaca actatagaaa agggattaat ttacactctt
    19501 catcaggata caccagtaat agcacctaat atgctggaaa cagtatggtg tgctgtcaat
    19561 agaattacaa aaaaaggtat acaaatagga gaaaatgaaa agataagccc attagatgct
    19621 ttaaagggtg ttactataaa tgcagcatat caatattttg aagaagataa aaaaggttca
    19681 attaaagaag ggaaattagc taatttgata atattagata aaaacccact tacaatcgac
    19741 cctatgaaaa taaaagatat taaagtattg cagactataa gagaagggga agtattgtat
    19801 tctttgaagt agatgaaagt tagatatttt ataatctata aaaaatagtt ttatataata
    19861 agttaggtag aattaaataa gattacagtt aaatcaacaa ttatattttt attaaatttt
    19921 aattattgta ttgaagattt ataagtataa ttttattgat tctacctttt taaataactg
    19981 tcgatttatt aaagttatct atgtactata ttaaacaatt aagtagttat taattgaact
    20041 tattagttta ttaaaaaact atgtatatta ctttgcagta agactttgga actaaatcta
    20101 taatagcaaa tttaaattta ttaaatagat taccttataa catttcatat aaaatatatt
    20161 gtgaatctca gaaaattact atttttcttt gagtattttt tgtaagcagt tctaaaagat
    20221 tcaatttcat acctattact tgaatcattc atcaaaataa ttctaattta aaaaataatt
    20281 ctatccaaat aatagatata taggactatg ttataatata aaaaaattta tataaaagtt
    20341 aataactata caagattgat aaagaaaaag tcaaaataga taattgatta gcaaaataga
    20401 tataattata atgaagttaa atctagcaat attctcctaa aattaaattt catttattta
    20461 attaaatata atttgacaat gggcaaaaaa gtgagtaaaa tataaataaa ataaaaataa
    20521 caggttcgga taaagaaaaa ggtttcttaa cctcaagcat aaagtatatt atctaagtta
    20581 tttgagatta agagataaat ccaatcttag gtactgagga ggaaaaaatg cttgatataa
    20641 aaagaataag agaaaattta gattgtataa aaaaagcaat ggaaagaagg ggcgaaaaag
    20701 actttaacct tgatgaagta gttaagttag atgatgaaag aagaaagatt cttcaagaag
    20761 ttgaagttat gaaaaatgaa ttaaatacag catctaaaaa tataccaaat cttataaaag
    20821 aaggtaaaga tgtagaaaat gaaaagatta aactaaaaga gttatctgat aaaattaagg
    20881 taatagacca aaatcttaaa gaagtagaag ataagatgga atacctatta atgagaatac
    20941 caaatgtacc acatccagaa gtaccacaag gtgaaactga tgaagataat gttgaagtaa
    21001 gaacttgggg aaagactact acctttgatt ttgaatctaa ggctcattgg gaaattggaa
    21061 cagaattagg tatacttgat tttgaaacag ctagtaaaat aactggttca agatttactc
    21121 tttacaaagg attaggtgct agattagaga gagcattatt aaatttttac ttagacacga
    21181 atacaaaagt aaatggatat acagaagtta ttccaccatt tatggcaaat agaaatagtt
    21241 ttttaggtac aggacagtta cctaagtttg aagaagatat gtttaaaata gaaggtctgg
    21301 actattttat gattccaaca tcagaagttc ctttaactaa tatacatgct aatgaaatac
    21361 ttaaatttga acaattaccg ataaattata cagcttatac tccatgtttt aggtcagaag
    21421 ctggttctgc tggaagagat acaagaggtt tagtaagaca gcatcagttt aacaaagtag
    21481 aaatggttaa aatagttgca ccagaagaat cttacaatga gttagaaaag cttactaaca
    21541 atgcggaaac tatgctacaa ttattgaatc tgccttatag ggtagtaaag atatgtacag
    21601 gtgatttagg atttacggct tcttttaaat atgatgtaga agtttggatg ccaagttaca
    21661 ataggtatgt tgagatttca tcttgttcaa actgcgaaga tttccaagct agaagagcag
    21721 gaataagatt taaaagagat aaagattcta aagctgaata tgtacacaca ttaaatggct
    21781 ctgggttagc tattggaaga agtgttgcag ctatattaga aaattatcaa caagaagatg
    21841 gttctgtggt tgttcctgaa gttttaagac catatatggg agtttctgtt attaaataag
    21901 agttaaatta tgtattttta agcaatacaa taatatagag gtaataaaaa ataattaata
    21961 taaaagtgat acaataatat agaagtaata aaaaaatagt taatataaaa gtgatacaat
    22021 aatatagaag taataaaaaa atagttaata taaaagtgat acaataataa tagaagtaat
    22081 aaaaaaaaat aattaatata aaaatgtgta caaactaatg aatattgata tagtaagcta
    22141 tcatatgaaa gagtatgtac acattttttt tactaatttt tcacaatatg aacataaata
    22201 atttacagga aaggaatctt ttatgaaaat tcaaaatact gagtggggat atattgaatg
    22261 gaaacatact tatgatgaaa ataatccaaa acaagctatg aatatataca ttgcagtaac
    22321 tatgcctggt aagaaacatt ttaatcatgt tcattatggt caagagcaga tgatatatat
    22381 tttagaggga gagggtttgt atattataaa tggagtttgg aagccatttt atcaaggtat
    22441 gattttttat atagaatctg gtagcacaca tgaaactata aatacaggcg atagagaaat
    22501 aaaagaactt attgtttcaa ataatgtaga tgatgtagga gagagtgaag ttatagatat
    22561 taatcctaat aattatttaa agaagacctt gataaattat agtgaaagta cattaaattt
    22621 gtatgcagca gtagaatcaa ttcgtggtca atttatagac ccgtttaaaa ttccattaat
    22681 tatatatgat gattcatgga atatagtttt aaaaaatcct tattttccac ttttttgttt
    22741 tgaaaaatgt aatcctatga aatttcctca aaattgtgat tgtatgaatc aaaaaagtag
    22801 caatcaattt gtatgtgaat atgggataac tatatataat ataccaatac tgtacaaaag
    22861 caatagcata ggtgttataa gaggagggta tgtactatta tctgatttga atttagatac
    22921 agagcataat aatttatatg atattccaga gggagctgct agaagtataa aacgcctctt
    22981 gaaacaaata tctaaaaata taataaattt ttgctctttt aatgatataa gaaaggattt
    23041 acaagaaaaa gagaagacta tagcaagaac atatcattat ggagagcaac ttgaaatgaa
    23101 tttaaaagta gctcaagata tggttactaa tttaagaata aatcatcact ttttatttaa
    23161 tacattaaat tcaatggcaa gcatagcact agatgatggt agttatgatt tgtatagtgc
    23221 aataatagat ttatcaagaa tgtttagata tacaatgagg tctgatttaa gatttgtaga
    23281 attagaatct gaaatattat acattaaaaa ttatttgaat ttacagaaat tacgttatgg
    23341 agatgcactt aaagtaaaat atcttattcc agagaagtta tataaccttt ctgtgccttt
    23401 taactttatt caacctattg tagagaatgc atttacacat ggatttagag atattgacac
    23461 agaaaagcga attgaaataa ttgcaagatt agattctcag tatgccatta tagagattca
    23521 taataatgga actatcttag atggaaataa tatagacaaa ataaaggcag gtattcgtag
    23581 taataatggt catggtttgt ctttaatata tacaaaattc acatctgctt atggaaataa
    23641 ttttgatatg gatataaagt cgagtgataa tgaaggaact tacataatga ttaaaattcc
    23701 tattgaaaat tataaggagt atgtatagaa cttgtgaaaa attaataagt tttataaatg
    23761 ttaagaaata tattagatgt ttttatgttg ttttatatat cttacttttt tatattatta
    23821 agctaaaagg gaggtattct catgagaaga gcactaataa tagatgatga agaagctgtt
    23881 ctaaaaataa taacacattt tatagaaatg aaagatatgc caataaaaat tgttggtaaa
    23941 gcaacatctg gtgatgaagc agtagataaa atcattggtt tagagccaga catagttttt
    24001 atagatattc aaatgccaat atacaacggg ttagaagtaa tagaaaaaac atctcattta
    24061 tctaaaaaaa taaactttgt agtaataact gcatttaact attttgaata tgctcaaaaa
    24121 gctttgagat taaatgtaaa agatatactc cttaaaccat tggatatgaa agaatttact
    24181 aagtctgtag aaaaaattat tggatatcaa tataccaata atgatttatt aaatgagata
    24241 ctggaatata taaatctaaa ctatagcaat gacttaaagt taaatgattg tgctagatta
    24301 tttttaacca atccatctaa tatatctagg atttttaaaa gtaatttaaa tacaactttt
    24361 atatcatatc taaatcatat aagaatagaa aaatctattg agttacttga aaatactaca
    24421 aaaagtataa atgagattgc agaaatagtt ggatataata gcctaaataa cttttataaa
    24481 aactttaaga tagaaaaagg aatgactcca aaagtttata aactgaacac taaaaattga
    24541 aattgataaa taaaaagtca atatagataa ttgtttgagt gtgtctgaat aagtatactt
    24601 taattatgat aaaaattaaa gcgctttaaa catatttaat aatattaaac cttataaaag
    24661 ctgtacctat ttatataaaa aaatatatat aaataaaaag aaaaagatat acaaaataaa
    24721 aaaagtgaat taaatactgt ttcaaaaaga cagaattttc atttaattta ctgagagttt
    24781 atatttctta aaggaaggta actttataat ggaggtaatt taatatgtca gacaaagtga
    24841 atatgaaaaa tattatctgt attgcaggcg cttatctagc aacagcaatt ggttctgggt
    24901 ttgctactgg tcaagaaatt ctacaatttt ttgcctcaca agggtatatg ggtttaattg
    24961 gagcattaat atcaatggta ttgttttcat ttcttggtgc tgaagttata actagaggta
    25021 gagaattaaa acttaaagaa ccaacaagaa tttacacttt ttattgtggg aagattttag
    25081 gaaaatttta cgaatggttt agtccaatat ttttatttgg gattcttata gtaatgattt
    25141 caggtgcagg ctcaacttta actgaatact atggtataaa tccttactta ggaagagtat
    25201 tgatggctgt tgctacttta attacagtgt ctatgggttt agaaaaatta gtaagcatac
    25261 ttggacgtat tggaccagtg atagcagtat ttacaattgc tgttggatta ataagcttgt
    25321 ttaagcattt tgatggttta tctatggttg gagaagctat gaaaaatatt gaagttacaa
    25381 aagcatcaga aagtccaatc gtttctggtg taatatataa tacattaaat attattgtaa
    25441 tgattgtttt tttaacagga atgggagctt ctattgaaag caaaaaggat gctttttggg
    25501 ggggtttatt aggtggaata gtgtttatga ctgctggtat agttatgtat ttggctatga
    25561 tttcagatat aggaaatttg tatatgaaag aaataccatc actttattta gcagataata
    25621 tatctccgat tgtaggtgta tgtttttcag ttgcattaat attaggtatc tatacaacag
    25681 ctgttccact tttatggtct gtaaccaata gaattgttga agatgaacat cctaaattta
    25741 aattggtaac aacagtaata gctattttgg cttgtatagg aggtttttta ccgtttggta
    25801 aattagtaaa cattttatat ccatatacag gctatatggg gcttttaatt ttagtctgta
    25861 tggtgtataa agcaattaca tgtagaaaaa aatcaacaca aagtcaggaa tagagccact
    25921 tattaatagt ttttatttaa agaaattttt tatataatcc gaatttaaaa agtcaaaata
    25981 gttaaataaa ttgtaaaaca tgataatata tttaattaaa ataatatagt aaaatataaa
    26041 tataaactaa aattaaattt ataaaaaata tctttataaa gattattaac ttagataatt
    26101 tgtagttaaa ttataaaaaa taaaaaaata aaattttgga gaggtgttag tatgcatgaa
    26161 cttattttaa tctcagaaaa gtataaagaa gatattttag atttttttac agatattcat
    26221 atgcaccccg aattaagttt taaagaattt aggactacaa aagctataaa agatttatta
    26281 gtaagtttag acatagaaat attagattta ggaatggaaa caggagttgt tggattatta
    26341 aaagggaagt atgatggtcc cacagtagca ctaagaggag atattgatgc attgccaata
    26401 tatgaagagg ttgatattaa gtataaatcc agatatgatg gtataatgca tgcatgtggg
    26461 catgatatac acacgtcttg ccttgtagga tgtgcatatg tattgtctca tattagagat
    26521 agtcttcatg gaaatgtaaa gtttatattt caaccagccg aagaagtcaa taaaggtgcg
    26581 aagatgctag tggaacgagg agtaatggaa aatccaaaag ttgatgctat atttggactt
    26641 cataatcatc cagatatacc ttgtggaaaa ataggtgtta agttaggtgg gttaatggca
    26701 gcagtagaca ctattaagat agaagtaaat ggatttggag gtcacggagg tataccaaac
    26761 agaacaatag accctatagt agcatcaagt gcaattataa tgggtattca aaccatagta
    26821 agcagaaaca taagtccatt agaatcagct gttatatcaa taggtactat aaatggaggg
    26881 actgcaaata atgtaatttc agaaaaggta gatatgacag gcacatgtag aagctttagt
    26941 aatgaagtac gaaagaaaat atcagaaaat ttagaaaata tagtttgtga gatagctcgt
    27001 ggatatcaag caactgcaaa gctagattat ttatttgatt taccagctgt tataaatagt
    27061 aaagagatgt acgcaatagc ttgtaagtct gtgtgtgatt tgtattcaga agatgctata
    27121 gttgatccaa taccttctac aggaggagaa gatttttcta tattcatgga aaaagcccca
    27181 ggattttttt actggttagg ggtaggcaac aaagaacaag attgtatata tcagtggcat
    27241 aatcctaaat ttaaagctga taaaaattct atattagtag gtacaaatgt actatgtcag
    27301 tctgttataa attatatgga taaattaaaa aataaaattt aagatagagc attctggaga
    27361 taaagtttat gagggggtat tagtttgagg aaaattaatt cacaggaaaa aaacaaagat
    27421 agtggattat tgatgagggc actaaatgtt gtagagagag caggaaataa acttccagac
    27481 ccagtaacca tatttttatt actatgtata attgttgtaa tattgtcagc agttatatct
    27541 aatttaggag tagaagaaat acatccttct acaaaagaag ttgtaaaggt agtaaatcta
    27601 ctagagaaag agcagattca atcatattta ggtagcatag ttacaaactt tcagtcattt
    27661 gctcctttag gattagtact ggttacaatg cttggagcag gtgttgcaga gaaatctgga
    27721 tttatggaag tgttaatgaa aaagggtata agtaaagttc cacaaaaact tgtaactgta
    27781 gcaatcgtat ttgcaggtat gttatcacat acagcagcag atgtaggatt tataatatta
    27841 ccaccacttg cagcacttgt gtttttagga attggaagac atcctcttgt aggtatgttt
    27901 gcagcttttg caggtgttgc agggggattt gcagcaaatg ttatgcttag tactacagat
    27961 gtattgttag ctggatttac aataccagca gctcaaatga tggacccatc ttaccaaggc
    28021 aatccagcaa tgaatcttta ttttgctttt atatcagcga tagttttaac ttttgcagga
    28081 gcatttgtaa ctgaaaaatt tatagctcct cgttttacaa aatataatga ttcaacaaat
    28141 gataaggata tacaggaatt gagtgaactt gaaaataagg gtataaaata cgctttatta
    28201 tcattgttag ttgtagtagt agtgatagtt gccttatgta taggtgacaa tgcatttatg
    28261 aaagatccag agactggttc tatactatct agtaatgcac ctttaatgaa aggtatagtt
    28321 cctataatca ctattatatt tttaactcca ggattagtgt atggaaaagt aagtaagaag
    28381 ataaaaagtg acaaagattt agtatctatg atgggtagta gtatgagtga tatgggtgga
    28441 tatatagtcc tagcatttat agcatcccag tttattaatt tatttaatct tagtaactta
    28501 ggaacaattt tatcaataac aggagcaaaa ttactagcag agtcgggaat acctagctat
    28561 ggattgataa taggatttat attgctatct ggatttatca atttatttgt aggaagtgct
    28621 tctgcaaaat gggcgatttt agcacctata tttgttccca tgtttatgct actagacttt
    28681 aatccagcat taactcaaat agcttatcgt attggagatg cttcaacaaa tccaataagt
    28741 ccactttttc cgtattttcc agttatattg gcctttgcca gaagatatga taaagatata
    28801 ggtataggta ctgtcatatc gaatatgatt ccatactcag tggtatttac attaatagaa
    28861 ataataatat tgttactatt catgggtatt ggtataccat taggacctgg tggaggaata
    28921 tcttacgttt tatagaccgt tataataaat ttatcaatga agattaaact aataaaatat
    28981 attctttaat taagaggagg attattatgt taaaaacaac aaaaatttca gacccagagt
    29041 tatacaagat tgtagctgat gagttggtta gacaagaaca caatattgag atgatagctt
    29101 ctgaaagtac agcaccaaca gaagtacttg aattaagtgg atgtgtattt acaaataaaa
    29161 cagaagaagg ctatccaggg gctcgttttc aagcaggttc tgaagaagca gataaacttg
    29221 aaaccctagc aataaaacgt gcaaaagaag tatttggagc agaacatgta aacgtacaac
    29281 cgtattcagg ttctacagct aactattgtg tatattcatc aatattaaaa ccaaatgaca
    29341 ctgttttaag tatgcgtctt gaccaaggtg gacacttgac acatggtagc gcagttaatt
    29401 ttttacatga catttataaa tatgaatttt atggggtaga cccaaatact ggacgtatag
    29461 attatgatgc tcttgaagca aaggcaaaag aatgtagacc aaaacttata attgcagggg
    29521 caagttcata tccaagatta atagattatg aaagaatatc aaaggttgca aaagaagtag
    29581 gagcttactt tatggtagat atggcacatg ttgcaggatt agtcgcagcg aaagtaatac
    29641 ctagtcctgt accttatgca gattttgttt cttcatctac gacaaagact ttctgtggac
    29701 caagaagtgg tattgtactt tgtaaagcag aacatgcaaa gaaactcgat aaaggtgttt
    29761 ttccaggaac attagggtct atacatctta atacagttgc ggcaaaagcc ttttcactat
    29821 tatatttaag tacagataaa tttaaaaaga taatggagca agttgtagta aatgctcaga
    29881 ctctagcttc tgaactgatt tcacatggtt ttagtattgt aagtggaggt actgataatc
    29941 atatagtaat ggttgactta agaagtaaga atcttacagg aaaacaattt gaaaaagctc
    30001 ttgaatatgt aggaataaca gttaataaaa atgttatacc tgacgaccca caatcaccat
    30061 ttgtaactag tggtattcgt ataggtctta catcaatatc tcaaagaggt ctgaaagaaa
    30121 aagaagttat acagatagca gggataatga ataaggtagc agaaaatatt gataataaag
    30181 aagtattaga tgaatgtaaa gcagaggcac aagaacttat atctaagttt ccattatatc
    30241 cagaagggta ttttgaagat taaatatttt gatttgtata gctcacaatt tataaagcct
    30301 gtaacataaa atttaataat atataaccac tataaggtgt tgattaatca acaccttatt
    30361 ttttttgaaa agtaatatac aagctatcat aagcatataa ttccttatag ataattaaca
    30421 agggggataa agttatgagg tattataata aacctaccaa agaagtatta aaatacttaa
    30481 aaacaaatcc agaaattgga cttgatgata atgaggtaga agaaaggaag cttagatatg
    30541 gattaaatga atttactata aaagaaggta gaacattttg ggacgagttg ggagaaagtt
    30601 tgacagaacc tatgatatta attctcatag gagcagcagt aataagttct tttgtgggag
    30661 aattacatga cgcattaggt attttagggg ctatttttat tggaatttct ataggcataa
    30721 taactgaagg aaaatctaaa aaagcagctc atgccctgtc aaaattaaca gaaaatatag
    30781 aagtaaaggt gcttagaaat gggaagataa ttaaaatatc aaaaaatgat ttagtaccag
    30841 gagatattgt atatatagaa actggggata tgataccagc agatggaaga cttatacagt
    30901 ctataaattt gaaacttaga gaagatatgc taacaggaga atctgatgat gtagctaaga
    30961 atgctgatgc tgtattagat atggaagtag tttattctaa aacagaaata atcgaacagg
    31021 atgcaatacc tgcaaagcaa gtcaatatgg tatttggagg gactcttgta gcatatggta
    31081 ggggcataat ggttgtcact catactggtg ataagacaga gatgggtaag atagcacaga
    31141 atttatcaaa tgaagaccag caaactccac ttcaaattaa attagggaag ttgggtgcta
    31201 aaatagcagg aatatcaggc ataatagcta ctttattgtg tatgtttatg attatacaga
    31261 tgcagagaaa aggtatgtta attttagata caagcagtat attatctttc ttacaatcat
    31321 tagaacctgc taaaaatgca tatatggttt gtattgcatt aatagttgca actgttccag
    31381 aaggtttgcc aactatgata aatattacct tagctataac aatgcaaaag atggcaaaga
    31441 taaatgcatt agtaacaaag aaagaagcct gtgaaactat aggttctgtt tctgtaatat
    31501 gttccgacaa aacagggact ttaacacaaa acaaaatgat ggtagaggta gcatatgttg
    31561 atggtaaata tataagtgga ggagagtatc aaagtaatag ctattttgaa caaaactgta
    31621 tagtaaactc aactgcagat atagaaaaag aagataattc atttaaatat ataggaagcg
    31681 caacagagtg tgcattactt ttatatcata atgataagaa ctataatgaa atgagaaaac
    31741 aaacgtattt gatatcacaa ataccattta gttcagaaga aaagaagatg tcaacattaa
    31801 ttcgtcaaga ggattcagat atattacttt caaaaggtgc tccagaagta ttattaaaaa
    31861 aatgttctta tgtacaacaa ggaaaaaata ttgttccaat aactccaaaa gtagaaaaaa
    31921 gtattttaga tgagattaag aagttacaaa ttaaatctat gagaacatta ggatttgctt
    31981 ataaaaaaat gagtaattct aaaacagaag ttgcaatgac ttcagaaggt gaattgaatt
    32041 taataggaaa ttcaagaagt tatatgaagg aagataattt agtttttagt ggatttgtag
    32101 gaatagtgga cccattgaga gaaggggtca aagattccat tgataaagca tttaatgcag
    32161 gagtagatgt aaaaatgctt acaggagata atataaatac agcaacagct attggaaatg
    32221 aattaggatt attaaatgat gggaaaaagg cagttgaagc aacatatata gatgtattga
    32281 cagataaaga attgagagaa gaaatcaaag gaatatctat tgttgcaaga agtaaaccag
    32341 atacaaaaat gagaatagtt tcagcacttc aaaaaagtgg cgaagttgta gctgtaacag
    32401 gtgatggtat aaatgatgcc ccagcactta gtcaagcaga tgttggaatt gcaatgggta
    32461 tttcaggaac agaagtatct aaaaatgcag cagatataat attgactgat gatagcttta
    32521 gtactatagt agagggaata aaatggggaa gaggtatata tgagaacttt caaagattta
    32581 tacagtttca gcttactgta aatatagtag catttataat tgctataata tctcaactta
    32641 ctggtaagga tatgccattt actacaatac aattattatg ggtaaatata ataatggatg
    32701 gtcctccagc cctagcatta ggattagaac ctgttagaga ttatgtattg aaaagaaaac
    32761 caataaatag acattctgga ataatagcta ggtctatgtt tgtaaatatt attataaatg
    32821 ctattcttat aattacaatt gtatttactc aatcagcttt taatatattg ggagctacat
    32881 cagaagaaca aggtactgtt atattttctt tatttgcatt cagtgccctt tttaatgcat
    32941 taaattgtag agagtttggt ttaaatagta caataccaaa tttctttaaa aataaactgg
    33001 cattgcaaat aatagtagtt acagggataa ttcaaataat atttacacaa gtgttccaga
    33061 gtttctttaa ttctgtttct ttggactttg atatgtggat aaagataata ctatttgcat
    33121 ctactatcct attatcaaat gaatttgtaa agctaattct tagaacaatg aaaaatagta
    33181 gaactatgaa ctttaatagt aaaaattaat tcttatgaaa ccgtaaagta ctatatattg
    33241 taactttgcg gtttttgttt gtttaatgtt gttttatatt accattttca tatttaattt
    33301 tttattaatc tgaacacaat cttccattgt aattgcttca tctgtgtcaa cacattcaaa
    33361 gtcaatatct aatttttgta atattttgta tgcctctttt tgcaaaggag tatcaaattt
    33421 aataggtgat tttatgtaaa tatcactgat aaaaaacatg atttatttca ttcctttcca
    33481 tttaaaatct tatagttata gtgtatcata aggttataaa atatagataa atatagtata
    33541 aatttaaaat atgtacagac aaaacaaaaa aatcatattc taagtaatac ttgggaaaaa
    33601 tgatattatc ataataaata atctttgtaa aaacttatat agaatctatt aaacagacac
    33661 taagccataa aaactttacg aaatataaaa ttcgtatcta aatagatata tagaatgata
    33721 ttttactgga gtagagtgat ttttaagaat tttatatata aattatgtta tcataaataa
    33781 agatatagat tataaaattt gttaataaaa taaagggcag ggaggtaagt ttcatgtttt
    33841 ccaaaatcct agtcaaaaca tttatcagag atagcgaaaa cgttcaaaat acagatgtta
    33901 gaaataagta tggttatgta gctggtgtag taggtatatt atccaattta cttttatttg
    33961 tgataaaggt attcatagga atgctcacat ctagtatagc tataatggct gatgcattta
    34021 ataatctttc tgatatggca tcttcagcaa taactatgat aggttttaaa ttagcaagta
    34081 agccagctga taaagaacac ccttttggtc atggaagaat agagtattta tcagcattaa
    34141 tagtagcatt tatggtgatg ttggttggac ttcaatttgt aaagtcatct atagaaagga
    34201 tagtaaatcc aattcctgta aaatttgaag taataccact tatactttta attgcatcta
    34261 taatgattaa aatctggttg agtcgtttta ataaatttat gggaaataaa attgattctt
    34321 cagccttaaa agcagtttca cttgatgctt taggagatgt atttacttca agttgtgtag
    34381 ttatatcatt tattgtagct agatttacta attttcccat agatggatat gttggtatcg
    34441 tagtatcatt agtgatactt tatgctggtt tctctcttgt aaaagatact ataaatcctc
    34501 ttttaggaga agcaccggat gaagaaatgg taaattctat tatagagcta ttgttatctt
    34561 ataaatatat aataggtaca catgatttaa ttattcataa ctatggagtt ggtagatgta
    34621 ttgcatctat acatgcagaa attccatcca atatagatat aatggaaata catgaaatta
    34681 tagatactgc agagagagaa atatctgaaa aattagatat atatctagta attcacatgg
    34741 acccaatatg tcttgaagat aaagaagtta tgtcagccaa aaaagaactt gaagaaatac
    34801 ttaagaaaaa tagtcttgta aaatctatgc atgattttag aatagttgga aaaggaagca
    34861 agaagaattt aatatttgat atagtagtta atccttccga attttccaaa aacatgtcag
    34921 aagatgactt aaaagaagat ataacaaaat tagttaagga gataaatcct gaatataatt
    34981 gtgtaattgt tgtagataag gattttattt aattattaat taatctcatc ataaggtaaa
    35041 aaatgtaaaa aggatagaca atagtataga ggcataatat aatagaagta tataattgta
    35101 tttttaatat aaataaagca attttaattg tttttatgaa atattataga gatgttgaag
    35161 tatattctat tattgggcac cttatggata tactgagtca gtggtgcaac cggctatgaa
    35221 tataaattta tttattttca tagctttttt tgtataattt tttagtaaaa attactttat
    35281 atatgatatt aatggaagat tagattataa attataggta acctaaaggg gtgagattta
    35341 catgaagaaa ggaaatagaa aggcattatt aattagttta attatgattt taagtatggt
    35401 ggtgtctaca atatatccaa ctgtatctta tgcttcagaa ttaggagaga atagtcagat
    35461 tcaaagtggt tcaactaatt catcaactgg agaggagaag gaaagcgaca ataaaaagcc
    35521 agaacagact ccagagaaag ataaggcaac agataataaa aaaccagaac agaccccaga
    35581 ggaagaaaaa ccaacagata ataaaaaacc agaacagacc ccagaagaag ataagtcaac
    35641 agataataaa aagccagagc aaactccaga aggagaaaag ccaatagata ataaaaagcc
    35701 agagcagata caagaagaag ataagtcaac agataataaa aagtcagaac aagctttaga
    35761 agatgaaaaa ccactagaca ataaaaatac agaaaaaact ccagaggaag ataatctatt
    35821 agaagatgaa aatttattga aagttttaga agaagaactt aatgaagaaa atgaagacta
    35881 tggatttgtt gtaaaaatta ataacaatac aatagaaacg gaatcaatga aaaaaatatc
    35941 atttaattta acttatactc caacatcaaa aggaatacaa gcaggagatt caataacttt
    36001 taaggtgcca gatgtattca ataaagttaa tttagattat acaagtgaat gctttgataa
    36061 aacagaaagt aatggagagt atacacttac atttagagaa ttacctaatg gccaaagtgt
    36121 aatgcaaggt aaaataggtt tggaagcata tgttaaaaag gttgatgaag atactaatgc
    36181 aaaaatacat attgaaacta ctggaaaaat agaaagtgga agtggagata tagatgtaga
    36241 aataaaacct ggagataaaa cggatgttcc agatgctaaa ggaatactta aaaagcttgt
    36301 tgaaggaaaa aaatcaacta ctgtatttat gccagttaaa aataaggata taaattacag
    36361 tatacaagta aatgaaaagc aggaagagtt aaaagatatt attttgtatg atgagcttcc
    36421 tgaaggattg acattgataa atggttctgt aagtgtagta acaagtgatg gaaaagaagt
    36481 tagtgatttt aatattgaac agagtaaaaa ttctatttca gttaattttg gaaatataga
    36541 taaatcgtat actgttaagt ataaggctag aatcagtgac aaaaatgcaa aacatggtaa
    36601 taaatataag aatgtagcta ggattgaatc tgatggtaag aagatacaag aagatgatgc
    36661 tactgtaagt atatttgata gaggagatga ttatcttctt actaaaggac attcaggagc
    36721 aacaaatatt actcaagttg gtcaagtaat aaactatcag atttcaataa atgatgataa
    36781 atcaccaata agtaatgttg ttataacaga taatatacca gaaggcatga gattaactac
    36841 ttcaggagaa gctgggcatg attttagagt tgtagaaatt ccaatgaatg ggagctggac
    36901 tccttggagt aaagaaaaaa ttgccaataa tatttcatat gaagtagaag aaaaaagaaa
    36961 tgaaagtggg caagtagata aagttataac tggatttaca attaatctca gtaaagaaga
    37021 agtggaatca aagtttttta tagcttatac attaaaggta attagtattg aagatagcta
    37081 tataaataga gctgttcttg atgcaaataa tagtgaaatt gataaaaatg atgagataaa
    37141 ctttaagaaa aattctggat taataagcgc aaaaaaagaa gttgataaaa aagttttaaa
    37201 cagtagtgat aaccagattg ttaaatacaa aatcaatatg tcaacttatg gagtttatga
    37261 tgcaggacaa gtaaatcttt tagatgaagt aaactcagtt ctagaaatat ctaatataaa
    37321 atattctgat aatcttgaac ttaaaaaaga agctggagat ggaaaaaata caataagatt
    37381 agtaaataaa tacgaattta aacagataaa agaaggggaa cctgtgcaaa gttgggttac
    37441 atttgatgca aacttcacaa atgtaaaagt tggggagact atacgaaatg tggctcagat
    37501 taatggttca agtcctccag gagtagagac tactaagcaa ggttatgctt ttgaagctaa
    37561 aaaagtggat gctttagata aaaatgtact ttcaggtgct aagttcaatt tagaagatgc
    37621 atttggaaat atagtagtta aggatttagt tagtgatgaa gatggtataa ttcaatctag
    37681 tgtaaaaaac ccaggaacat attatttagt ggagataatg gctccacgtg gatatgaaaa
    37741 actgaaggat aaagttaagg ttgaaattgg taatgaagat attggtaaga tagtagatat
    37801 tgggaatata gaaaacataa gacaagaaaa tccaccagta aatccaccag caccaccaaa
    37861 tacagatgaa ccaatggtaa atccaccagt accaccaagc acagataaac caaggaaacc
    37921 atcaagttca tctgatacag aggatactat agttataaat ccaccagtac caccatcaga
    37981 agatataata aatccaccaa taccagaggt attgaatccg ccagtaccac catcagaaga
    38041 gatgatagaa actcctgtta aacagattat tccaatacca gaagtagtaa agccatcagt
    38101 gtcagaagaa aaaaataata gagttaaaga tgatactttg gtaaatccac cagtaccacc
    38161 aaaaacaggg gatagtacta caattattgg agaaatactt ttggttatag gagctattgt
    38221 aggacttatc gtattaagaa gaaataaaaa tacaaattag accctaacat tataaaaata
    38281 taagttatat taaaaaatat cttctaaaac aatatttaat aatgaaaata ttgttagaag
    38341 atattttttt ttgaagattt atgtaaaaaa ataataactt tttagaaaaa agttccaaag
    38401 ggatatagac aattaaaaag atataagcta taatatagat ataaaattaa atgaggcaaa
    38461 actagggaaa cctagtcacg caaagctata ggggctaaag tttagtaaac catgccagcc
    38521 agttgccgaa aagagtaaaa atttcttttt gtatatacaa agatactctt gggtatcttt
    38581 tttattttga aatttattac tcccggccta actcaaagga gggaataata tgagaccaag
    38641 taaaaaatta ttaatagcta taatatcaat attcttaata agttcagttc cagtaagtgc
    38701 acatgcagat agtactacta tacaacaaaa taaagacaca cttagtcaaa tagtagtttt
    38761 tccaactgga aattacgata aaaacgaagc taatgctatg gtaaatagat tagctaatat
    38821 agatggaaag tatttaaatg cattaaaaca aaataactta aaaataaaat tattaagtgg
    38881 aaagttaaca gatgaaaaag aatatgctta tttaaaaggt gtagttccta agggatggga
    38941 aggtactgga aaaacttggg atgatgttcc aggtttaggt ggaagtacag tagctcttag
    39001 aataggattt agtaacaaag gtaaagggca tgatgcaata aatttagaat tacatgaaac
    39061 agcacatgca atagaccata tagtattaaa tgatatatct aaatcagcac aattcaaaca
    39121 aatatttgct aaagaaggtc gttctttagg taatgtaaac tacttaggtg tatatccaga
    39181 agaatttttt gcagaatcat ttgcatatta ctatttaaat caagatacaa atagtaagtt
    39241 aaaatcagct tgtccacaaa cttatagctt tttgcaaaat ttagctaaat agagttttaa
    39301 taaatttaaa ataaatataa aagagatgct attataatag catctctttt atattgcgtt
    39361 taaatctaat aaattttgtc ttatgtataa ctatgataga ttatcaatta ctactcctta
    39421 tacaaggctt caacgtgttt attatgcatt tgagtaatta tcgtaggtat aatagaaatt
    39481 attgaaccaa ttactatcaa taaaattcct ataaccatgt ttatagggat aatttcttta
    39541 agtattaata atgctagtat tggagatatt actggtttaa agaagaatac taaagatgta
    39601 agactagtag atgtagcctc cattgccata aagtaaagcg cataaccaac acctgtaaca
    39661 aatacgaata cataaatcat aatgggcata ttgtgtaagg tatatccact aaaaataggg
    39721 atatttgcaa atacatgaag cttattttta tttaatatat ctgcgataaa attaatttta
    39781 gtgagtaaaa ccaatatcaa catttccaaa ctaccaaata taaagctaaa gcaggttaca
    39841 actattccac caaattttaa ggtttttctt ttaccaaata cagtatacat tgaaaaaata
    39901 atagcagaag ataatgttaa gaatattcca ctaagagtta gttttgtatg caatggattt
    39961 attataacta taattccaag aacttctaat ataagtgaaa ttacattgtg cctatatatt
    40021 ttttccttca aaattaagta agctaaaagc attacaaaga ctggattaca actgaacaaa
    40081 acagcaacta cagatgcctt tgtgtttaga acagccagtt gatacaatga catacttact
    40141 actacacaca taaaacctaa aaatgcaaag tattttaagt ctgattttgt aatagaaaga
    40201 ctaagagctc ttaatctttt tacagcaaaa ggtagtaaga ctaaaccgcc aacaaaaaat
    40261 cttgataaag ttatttgtaa gggattaaag tcattagtga cagtttttag actaatttcc
    40321 attgaactaa aaaataaggt agtcagtatt atataaacat aacctttttt caagtcaaac
    40381 acctccttgt aatttatatt agtactatag ataagaatat tcaagcatat tggaataata
    40441 tggtatgtat aaaatatagt acataaaatt ataaactacc ttaatataga atgtaagtat
    40501 tctatactaa ggtagttaat tatttgaatt actttgattt agttatttta aattatataa
    40561 tttggctaat ttttcaaatg ctggtaaaga acttttaact ttatcataag atacacaata
    40621 tgatactcta aaatgacctg gacaaccaaa agaagaacct ggtactaata ataaattaaa
    40681 ttgttttgca tcattgcaga attttttatc atcttcaatt ggagcttttg ggaacaaata
    40741 gaatgtacca ttaggtttaa cacaagaata tcccatatcg attaaactat tatatagaag
    40801 gtcaaaattc tttttataaa tatttacatc aacttctgca tctaaacttc ttgcaataac
    40861 cctttgaaaa agagaaggag catttacaaa tccaagtatt ctatttgcaa catttaatga
    40921 agacataaca tcatcaaaat catccatttg cccattagca acaatatatc ctatacgttc
    40981 accaggtaga gataatgatt tactataaga gtatcctata aatgaatttc tatagtattt
    41041 tagtacacaa ggaactttgg caccatcata aattatttct ctatatggct catcagaaat
    41101 taggtatatg cttgtattaa attctttttg ttttgaatcc aataattctc caagattttt
    41161 taataattct tcagaatata tgacaccagt aggattattt ggagtgttta ttattaaagc
    41221 tcttgttttt ggagtaatag cattttttag agcatctaaa tctggctcaa aagtctctat
    41281 atttgtagga acttctatta attttccatc atagttttct gtataatttt tatactcacc
    41341 aaaatacggt gcaaaagcaa taacttcatc accaggattt aaaagagttt ttaaaataat
    41401 atttagacca ccagcagcac cacaagtcat aattaaattt tctcttgtaa gatttaatcc
    41461 atctttttta tttatgtgtt cagcaatagc atctcttaca tcctcatatc ctgagttgtt
    41521 catatatcca tgaactaaat ttggagattc ttcatttaaa atatcattta taactgcttt
    41581 aatagtctct ggaggttcaa cacttggatt tcctatacta aaatcaaaaa cattttcctc
    41641 accataaata
//
LOCUS       DAFAZV010000037        41402 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFAZV010000037 DAFAZV010000000
VERSION     DAFAZV010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41402
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.037"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            273..1211
                     /gene="pdaA"
                     /locus_tag="KOU88_002659"
     CDS             273..1211
                     /gene="pdaA"
                     /locus_tag="KOU88_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBK3212528.1"
                     /translation="MFRKVLHYLTLLSISIFFIVGCSNSQNNQNENQNKETQLQEDKE
                     KIDSGKDTSNVIVSDGTDKPSKATTNNDNNKLDVSSLDNTTLDWFYIPNNKHKTPEVN
                     TDIEFKFSDYDALYNGPTKDGQKTLYLTFDEGYENGYTTKILDTLKQNQVKAVFFVTA
                     PYIKENKDLVKRMVSEGHIVGNHSKTHPSMPTKTSNLKNFNDELYDVEKLYKDVTGKD
                     MVKFFRPPMGKYSEKSLAMTKNLGYKTVFWSFAYRDWDTDKQPSHEEATQKIMDNLHD
                     GSILLLHAVSKTSTEILNDFISNARKLGYEFELLEY"
     gene            complement(1583..2956)
                     /locus_tag="KOU88_002660"
     CDS             complement(1583..2956)
                     /locus_tag="KOU88_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HBK3212529.1"
                     /translation="MVLTGAHYIYILFMVIILITMIMKKDTIVPCILGVFFMGLFFEK
                     NIFGAITAVFNSFIISLNELGPIILIIAIMVALSKALEANNAIQYMVRPFSRVIKNSN
                     TAFFVTGFVMLVLSWFFWPTPAVALVGAVFLPVAMRAGLPAIGVAVALNLFGHGLALS
                     TDFVIQGAPSITAGAAGVAVSYVINDGMILFWVMGIVTISMAFYTLKRDINKGMFREE
                     LKGFESEEVEEFNGKSKIATILVALGFLADIIAMYVFDLKGGDASALLGGTAVFLIII
                     INVINFGKDSLENVCENIIDGFVFGIKIFGAIIPIAAFFYMGEVAPLTGVFGKVLAPG
                     SQGLLSDIGIALSQTIPLNKFAVSGIETVVGAITGLDGSGFSGISLVGSLASVFGTAI
                     NASVGALAALGQISGIWVGGGCLVPWGLISAAAICGVSPIELAKRNFVPVITGLVVTT
                     IVAMFII"
     gene            complement(3143..4465)
                     /locus_tag="KOU88_002661"
     CDS             complement(3143..4465)
                     /locus_tag="KOU88_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3212530.1"
                     /translation="MINKIKPSKLGVILLIYVVISAAVAFILNIPFYSAVESIVKDVS
                     EGKVYFKREVNQLMDNFQTYVNNNGIRADDGDDIAKWNSDNWFVSMKIYKGNKVFYDT
                     LYYPNEVPDKSEENEFYSSPMARNYEIQFSDIKANIVVVALFRFRFQNFIEAISITFM
                     ALTFIITFLLLFSRKIKYLRKIEMGIKIVESGSLKYRIPVKGNDELSSLASSINEMSH
                     TLENQLIKEREMKNKNKDIVTSISHDVRTPLTSVICYLDLIKDHKYNSPEQLEQYIKN
                     VRSKAYQIKDLTDDLFTHFVNSGEEVSKGYEKINANEFIFQLLLDSSYTLEEKGFHIT
                     IENELYNQYHIYVDVTQFRRIFDNLCSNIIKYARKDKPIVFLIKVEDSKLLIIQKNRV
                     SNFSKNVESFGIGIKNCEKIVAYHNGSINVNSDDKEFAIEISIPAKES"
     gene            complement(4458..5162)
                     /locus_tag="KOU88_002662"
     CDS             complement(4458..5162)
                     /locus_tag="KOU88_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3212531.1"
                     /translation="MNKEIPKKILVADDNPEIREIVEILLTGEGYEVIMATNGEEAVN
                     LVDSTIDLIILDVVMPVKTGFVACNEIREKTTAPILFLTAKTQDSDKVIGFSAGGDDY
                     LSKPFSYSELISRVKSLLRRYYIYQGKEKEREPNILKTKELCVNLDTQDVTLNGEPVF
                     LTTIEYSILILMLKNRKKVFSSENLYETIWDEQYFYTANNTIMVHIRNLRKKLEKDQK
                     NPQYIKTAWGKGYYID"
     gene            complement(5345..6409)
                     /locus_tag="KOU88_002663"
     CDS             complement(5345..6409)
                     /locus_tag="KOU88_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBK3212532.1"
                     /translation="MISKTEKKNKCLGSVAFLVLLMGITGYFVFRGQSVESLIKSLKG
                     ASPMFILIGFAMMFIYVACEGINIYLGMKALNQKTTLLKCMGYAFIGFYFSSITPSAS
                     GGQPAQVYYMKKDDINISYSSLILLVIVVIHQVVILAYSGIMFIMEREFILNNVSGMN
                     ILLIYGVITNVALVIGVIAIIFSKKLVNNFIISITNLLGKLRIIKDVESSRKVIISQI
                     EEYVKGAQYIKQNPKLVVQILVITIVQITAMFLVPFFVYKAFHLSTYTVFEILAIQSL
                     LNIAVSSLPLPGAVGASENSFMTLFKIFFPGHLLVPAMLLSRGISFYAFVAISGLICI
                     VVHVKSSEKVKAVKKVAYVR"
     gene            complement(6412..7110)
                     /locus_tag="KOU88_002664"
     CDS             complement(6412..7110)
                     /locus_tag="KOU88_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK3212533.1"
                     /translation="MYVVGLIIVVALIFLVHSIIPTYYNKLLNKEVLKNMAGENEIAL
                     TFDDGPDKRYTEKLLDVLKENDIQAMFFVVAKNAEKEPEIIKRMLRENHIVGLHSLEH
                     RNAWLYSYNYVKKDFIESTNIMKNLGVDVNYYRPPWGHTNIFSNSFVKKYNLKMTLWD
                     VMAEDWEKDSTVDIIINKLMSRTKENSIICLHDAGENSGGAVGAPERTIEALKIAIPK
                     LKASGLKFVTPERM"
     gene            complement(7101..8198)
                     /locus_tag="KOU88_002665"
     CDS             complement(7101..8198)
                     /locus_tag="KOU88_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-diphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBK3212534.1"
                     /translation="MKVLILTGKFGMGHYSASNSLSEDIKAKFDNSEIIIKDIFEYIM
                     PNYSDKMYKTFSILVNRGSSLYNLFYKCAENGKKDIKFTFSDYFLNKLDTLLHEVQPT
                     VVISTFPFCSQLVSRYKEKYNSNLPLITCITDISSHSEWISKNTDCYLVASKSTKEEL
                     VFKGIDESKIKVNGIPVKKEFKRIEHVNHSTKKNILIMGGGLGLLPKSEQFYKELNSL
                     EGVKTTVITGNNKKMYYKLYGRYENIEVVGYTNEVYKYMKDSDLIISKPGGITLFETI
                     YSELPILAFNPFLQQEIDNASFILNNEIGRILGKNKKYYVDEIKDLIYDDATLKEMSS
                     NMKELKKQFDNNTLENILFSLDEQGACRECM"
     gene            complement(8521..9765)
                     /locus_tag="KOU88_002666"
     CDS             complement(8521..9765)
                     /locus_tag="KOU88_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBK3212535.1"
                     /translation="MFENLKKADPEIYESMKRELKRQQRNIELIASENIVSVPVMETM
                     GSHLTNKYAEGYSGKRYYGGCEYIDEVETLAIDRIKKIFGAEHANVQPHSGANANIGV
                     YFAMLKPGDVVMGMNLSQGGHLTHGAPVNISGQYYKFYEYGIDKDSGLIDFDEVRKIA
                     HEVKPKMIVAGASAYPREIDFKKFREIADEVGALLMVDMAHIAGLVAAGLHQNPCEVA
                     DFVTTTTHKTLRGPRGGVILCKEKYAKDIDKAIFPGIQGGPLEHIIASKAVCFKEALS
                     DEFKEYQVQVAKNAKALAEELIKRDFKLISGGTDNHLILLDLTNKNITGKAAEKRLDD
                     AYITANKNTIPFDPNGALVTSGIRLGTPAVTTRGMKEEDMAIIAEAIDLCLTYDEESK
                     ARTLVVGLTEKYPLYEEYNIMD"
     gene            10093..10881
                     /locus_tag="KOU88_002667"
     CDS             10093..10881
                     /locus_tag="KOU88_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBK3212536.1"
                     /translation="MNQNEELEYKKNILKLALFVGELMIKNGAETSRVEDSVLRICRS
                     RGFYHVNIFTTPTVIIISDEKFDGFSFMKTIQSRGINLNKISLLNSFSREFVSDKEYD
                     IDNAIARLYEIQDVKPYPLWLFYSCTGIASACFACLLGGNYVLNFILTFIIAIFAAIT
                     YDKTMKISAISAFSCLVSSFLIALSGVLLVEIGILDDPKMLIVGAIMPLLPGVAFIKA
                     IRDLISGNLISGISRAFDAAMIIIAIASGVGFVLDTWYRIGGPF"
     gene            10881..11354
                     /locus_tag="KOU88_002668"
     CDS             10881..11354
                     /locus_tag="KOU88_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBK3212537.1"
                     /translation="MTDMSMILHFLFSGVATAGFAVFFNAPLYLLLPAGVTGGIGWIV
                     YVYLFNFTTNAVFAGFIAAALVSACSETLARKLKQPAIVFVIPGILPLIPGIGLYNTM
                     LSLIQKNYSLAMSKGTDALFLSAAIALGVLVVTSFVRTLNLLKIRKNFIPYRKSK"
     gene            complement(11446..11886)
                     /locus_tag="KOU88_002669"
     CDS             complement(11446..11886)
                     /locus_tag="KOU88_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR reducing system RseC family protein"
                     /protein_id="HBK3212538.1"
                     /translation="MNQQGFIMEIVDDRTAKLKMQRHSACAACGKCATTNSAESKEIL
                     VEVDNTIGAKVGDHVEVSMDNMNVLKAAVMAYIIPLIALLVGTIGTYYILGAIGMTTG
                     VEAISGLVGICLTIICYLYLKKNDKKFRDSREFIPVITRILIDL"
     gene            complement(11901..12194)
                     /locus_tag="KOU88_002670"
     CDS             complement(11901..12194)
                     /locus_tag="KOU88_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBK3212539.1"
                     /translation="MEERKLAPNNEREALIKRLKRIEGQVKGIQKMVEQERYCVDILV
                     QISAIRSAINRVGTIILENHIKGCVAESIKHDDADKTEEMIKELMDTINKFTK"
     gene            complement(12237..12638)
                     /locus_tag="KOU88_002671"
     CDS             complement(12237..12638)
                     /locus_tag="KOU88_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212540.1"
                     /translation="MKKCLYCNRDIKSPNNKLAIKYDDNMNIYPCRAECKEKIEEYIA
                     KKPTYKFINILEVLLGVGGIFCFLSKWTIAAQVVLGIDALVIFLFPLAGFKMNGKLSM
                     EQTKNQSRSIAISILAFIVIITVLYFKQVGK"
     gene            12871..14991
                     /locus_tag="KOU88_002672"
     CDS             12871..14991
                     /locus_tag="KOU88_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3212541.1"
                     /translation="MKQMELAIVSLKKDAGEIYENQIRQFLGDNLKINLYSFEEGNLK
                     FFKEKLILLSAYLKYDEIVKLSHYDAQIIVPKLTFEKNSIDMISKLEKDKIIYVYNLS
                     KDMAIETISLIHRLGIDNINILPCYPEIEFTPTDAVILTPGEKILPKFKNCEVIDLKY
                     RIIDLSCIVEIATKTKLKHLIKDDLIKKYVEKIIPTSYSTGELLLDANKFERQFDLLL
                     SIIDDGIICTNNDGIIQFYNHMARKILSINANEMIDSFVGDCIKDINFQSILTNKTPF
                     FEKLIKINHIDINLEIKHIQLNVFDGFILKMTKFSQLEKKQAKLRAQLVNSGNISKYT
                     FDDILGSSIQTINTKKIANKMAQSNSSILIIGESGTGKELFAQSIHSASRRKDGPFVA
                     VNCSTFQENLLQSELFGYDEGAFTGAKKGGKIGLFELANNGTIFLDEIGEMDLNSQSK
                     LLRVIQEKQVRRIGSNNVIDIDVRIIAATNRNLKELVSKNMFRRDLYFRLNVLPLKIH
                     PLRERPADIFEIFGSLKYDIPCNFILSEEVKEIFKMYRWEGNVRELRNLGEYFCYLEK
                     DIIEICDLPEYILDTIDSNYSRTVCNKVSDNIKKYQFNIGKDKNIMKYDYNFKKSLDE
                     YIFILDNLKKAYDLKERIGRKSLCKIALEENRFLTEQQIRNMLLELQDFGLVDILVGR
                     GGSIITSKGVEFLKNINRSNKLNS"
     gene            15216..16382
                     /locus_tag="KOU88_002673"
     CDS             15216..16382
                     /locus_tag="KOU88_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3212542.1"
                     /translation="MNYNFNEIVDRSNNFSSKWSEMEKKYGTNDLLPMWVADMDFKAA
                     PCIIDSLKNRLEQEIYGYTTRPDSYNESIVNWLDRRHNWKIKSEWLIYSPGVIPAISL
                     LINELTKANDKIMIQEPVYSPFNSVVKNNNRELIISPLQKLENGNYIMDYEDIENKIK
                     DVKLFILCNPHNPVGRVWTKDELKKLGDICLKHNVKIISDEIHSDIILKKHKHIPMAS
                     ISKEFEKNTITCMAPTKTFNIAGLQSSYVVLPDEKDYKLLDDAFTRIDIKRNNCFSLV
                     ATEASYNNGESWLESFLEYLESNIDFAIKYINENMPKLKVRKPEGTYLLWVDFSALGL
                     SDEELESILVQKGKVALNQGNSFGIGGSGYQRINLACPRSMLEEALIRIKNAIN"
     gene            16407..17849
                     /gene="nhaC"
                     /locus_tag="KOU88_002674"
     CDS             16407..17849
                     /gene="nhaC"
                     /locus_tag="KOU88_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBK3212543.1"
                     /translation="MKMNTERKIPSFRYSLLVMLAIIALTSVGIVVFNASITTMFLLS
                     WLIVVPAAMKLGYTNDEIEAFGFEVGKDAFQSNLIILSVGVLIAAWIAAGTIPTVVYS
                     GLTIITPKYFLLTTLIVCSLTSVATGTSWGTLGTSGIAMMSIGTSMGIPLGLTAGAVI
                     SGAFFGDKMSPLSDSTNLAAAVCKTDVITHMKHMFYTTGPAYVICIVLYTVIGFKYSN
                     NTIDYVQINQIKDVLNSNFHIGLVAMIPIIFLLLLLLLQKPPIISILSSAIMGLIIAV
                     FQEGEKIGDVLNYMLSGFTIDTGFVYADKLLNRGGIMSMAETVLLVFVVFVIAGILQK
                     TGFLEVLLQPLITKIGKSRTKLVGSTFIVSYFANAFSSSMMFTSVFVGTLMSPIYKEF
                     KLKPQNLSRIIEDTATLGGPLIPWNSNAVFCAQTLGVSPLEFIPYCFLSWITPIISFI
                     YGVTGFTMLTYTDDEIEELEIFDTAQRRVD"
     gene            17852..18121
                     /locus_tag="KOU88_002675"
     CDS             17852..18121
                     /locus_tag="KOU88_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212544.1"
                     /translation="MKFEYYYLIQDIAGILLAFIGLRMSIIGFRILSMRGLSINTLLI
                     VIKYCLFTIAGLNLLISKFGIRHWIWSVCMLIISIIINPRIKVSK"
     gene            complement(18198..19625)
                     /locus_tag="KOU88_002676"
     CDS             complement(18198..19625)
                     /locus_tag="KOU88_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp14"
                     /protein_id="HBK3212545.1"
                     /translation="MKLTKSISSMLCLSLVLSLSPVAYANEISRTTVENTLVGQDRYQ
                     TAVEVSKKGWSSANEAVVVNSESIVDALAVTPFAKLKNAPILLTEKNNLNSQTEKELK
                     RLGVKKVYIIGLSSSVSNDVQKQLESNNLTTDRVGGSDRYQTALSIAKKIEGLKDISE
                     IAVVNGYTGLADAVSIASVAATNGMVILPVSDASGISSFKDFIESKNINKSYIIGSTN
                     AVSDKIKQSLPNSERIGGADRNETNGKVIEKFYTSNKLNNVFVAKDGMKNQNQLIDAL
                     AVGVLASKENSPVLIVGEQLSATQKSVFSNKNATSITQVGSGGNENAFKELKDLQANS
                     NNKRVMYVTNTDKVNIRNDATIEASVIGYLNNGDEVEVLDVLKTGWVKIKYNEGIGYV
                     SGSYLTNNKPDNSNENIKIKYVKEKDGLNVRKGPSTEDEKIGHLSYGSKVETIEMFAT
                     GWVKIKYNGGYGYVSNDYLSDTPVI"
     gene            19997..20866
                     /locus_tag="KOU88_002677"
     CDS             19997..20866
                     /locus_tag="KOU88_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3212546.1"
                     /translation="MDLLHLKYFQTVARMEHITKASHKLNIAQPALSKTISSLEKELG
                     VQLFDRKGRYIVLNEYGRLFLKRVDSILDLVESSKKELQDTSLENSGEVKILSPAAAN
                     VLPSLLSNFRKLYPNITFNVSHTLPSSYKKSDFDLYISSSFTKLNSENSITLTCEEIL
                     LGVSINHPLSLKDEVYLSEVSDENFIVITKGENYREVIDILCESANFKPKIAFESDSP
                     YTIYALIKSLQGVGFICGKSWGLSQDPEIKLLHIKDIEFKRYLNLSWFSENYESKAVL
                     LFKNFLINYFKNI"
     gene            complement(20978..21784)
                     /locus_tag="KOU88_002678"
     CDS             complement(20978..21784)
                     /locus_tag="KOU88_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase"
                     /protein_id="HBK3212547.1"
                     /translation="MGRKVKIGIIQQHSVLGNVKKNIEKAVEMIDDLGKQGADIICLP
                     ELFATGYNLESLGGVKTLELIREHNKYIEESMSEAAKRNNVYLISPYGTLEKGSTHVY
                     NSAVIFDRKGKIMGEYCKNHLWSLEAVYFKGGEKVEVYDADFGRFGVMICYDAGFPEV
                     SRELTLKGSEIIFIPSAWRIQDEDMWDLNVSQRALENTVYTVGVNLVSNDSNLILFGK
                     SKICNPRGTVITQLDTYREKYVLSEIDLDEIKKYREDIPYLKDRKSSYNI"
     gene            complement(21798..23030)
                     /locus_tag="KOU88_002679"
     CDS             complement(21798..23030)
                     /locus_tag="KOU88_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBK3212548.1"
                     /translation="MQEREELVLNPVPKEERVGWLAPLFNMLGSNIAISELMVGGTLI
                     LGMTLSNMIITSIIGNLILVAIIMIQGYIGYKEGLNTYVLAKGAFGEIGGKYLISLLL
                     GITSFGWFGVQAGVAGLSVQKIFPSVNLTLVTVILGLFMVVFALYGFKAMAKFNYLVI
                     PPLMILMVWGVFKAFSTYGVEAIYNYTPQTTMSMVEGLNIVVGLVIVGAIISPDQLRY
                     TRRVKDIWIISFLGLGIISLFQQVAAGVMSMGAPTWDITEVLANLGFGWVAFVILILA
                     SWSTNVSNAYSGGLALKTIFPNVKRNVLTLVAGLIGTIIAATGIIFKFQSFLSFLGIA
                     VPAIAGIMWCEYYFIQGRTYKHREGINWIAVISWLIGFAASYYSSKINFLIPPINGIV
                     VSMVIYYILMNCFGIKDK"
     gene            complement(23489..25276)
                     /gene="aspS"
                     /locus_tag="KOU88_002680"
     CDS             complement(23489..25276)
                     /gene="aspS"
                     /locus_tag="KOU88_002680"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBK3212549.1"
                     /translation="METLKGLKRTHYCGELREKNINEEVVLMGWVQKKRNLGGLVFVD
                     LRDTSGLCQIVFDTDVDKEAFEKAEKLGAEFVIAVKGKVCERQSKNPNMPTGDIEIFA
                     TELRLLNKSETSPIYIKDDDDVSEALRLKYRYLDLRKPSMQRNLKLRHKVMNITRNYL
                     SNNRFCEIETPFLIAPTPEGARDYLVPSRVNPGKFYALPQSPQLYKQLLMVSGMDRYF
                     QIVKCFRDEDLRADRQPEFTQIDCEMSFVEQEDVMSMIEGLLEAIFKEVLDVELALPL
                     PKMTYAEAMSKYGSDKPDTRFGYELTDISDVVCNCGFKVFADATQPGKSVRGINVKGK
                     ADDFTRKQISSLEEHAKTYRAKGLAWMKVGQEGVTSPIAKFFNEEEMNAILTRMNAEV
                     GDLLLFVADKNSIVFDALGQVRLEVANRLNLLDKNVYNLLWVTEFPVFEEDEETGTFS
                     AMHHPFTSPMDEDLDKLEEGDKSSLRAKAYDIVLNGYEIGGGSVRISNSDVQSRMFKA
                     LGFTEERANEKFGYLLEAFKYGTPPHAGLAFGLDRLVMLLAGTDNIREVIAFPKNQNA
                     VCPMTNAPTLAEDEQLEELSIKVDIKDNE"
     gene            complement(25350..26612)
                     /locus_tag="KOU88_002681"
     CDS             complement(25350..26612)
                     /locus_tag="KOU88_002681"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBK3212550.1"
                     /translation="MLTKAPRGTKDITPKEAYKWRYVENKFREICALYGYEEMVTPIF
                     EHTELFKRSVGDTTDIVQKEMYSFKDKGDREITLKPEGTAGVVRAFIENKLYADTQPT
                     KLFYVTPCFRYERPQAGRQRQFHQFGIEALGSDTPSMDAEIIALAVQFFNEVGLNDLV
                     VSINSVGCPVCRKEYNALLKEYLDSKADILCDTCNERREKNPMRVIDCKNPTCKENIK
                     DIPFIADHLCDDCKSHFDKLQEYLKEMNINFVIDKTIVRGLDYYRKTAFEIISNDIGA
                     QSTVCGGGRYDGLVEQLGGPKGISGIGFGLGIERLLLTLEGNGIEIENPQSTDIFIVT
                     IGEKANTRSFKLLKDLRQNHISADKDHIERSVKAQFKYSDKINSKFTIVIGDDELKND
                     TATLKNMKTSEQTTVKLSTLVEELKQKL"
     gene            complement(26602..28158)
                     /locus_tag="KOU88_002682"
     CDS             complement(26602..28158)
                     /locus_tag="KOU88_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="HBK3212551.1"
                     /translation="MLYVFLKGHDYKYEVAELIKLFTSEFKFKDSNADNNIESKHLIN
                     RLIYENGVLFSSTEYYENGNLKYESIQNIENMNLEFLDGFDSSKTIEEFLNSLDSESK
                     RNFKKLCKENIKKSMFVVLKQVFNSYVPWGILTGIRPVKIVHNLMDKKLDDNSIRTIL
                     KDNYFIIDEKIDLALEIAKRERLFMYPIDKNKISLYVSIPFCPTRCVYCSFPSNSLKQ
                     FGHLKREYVYKLIEEIKGFAKVIKDTKKEVETLYIGGGTPTTLDEEELDLLINSLFNE
                     LDLSKIKEFTVEAGRPDTITEQKLRVLKKHNVSRISINPQTMNDDTLVKIGREHRVSD
                     LVDCFNMARRMGFDNINMDIILGLIDEDLNMVKNTLEEIKKLSPESLTVHTLAIKRAS
                     NLNINMDRYKEHLTQYEEMVKMIDLSMKYAKDMGLNPYYMYRQKHMLGNLENIGYAKE
                     GYECIYNIQIMEEKQSNYALGAGAISKFVYVDEDRIERVENVKNVEQYIERVDEMIKR
                     KKEEVYKNVD"
     gene            complement(28249..28863)
                     /locus_tag="KOU88_002683"
     CDS             complement(28249..28863)
                     /locus_tag="KOU88_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3212552.1"
                     /translation="MIIKKFVDSYFGVNTYVLGDEKTKKCAVIDPGGSLVETLSFVKE
                     NELNIEYIILTHGHGDHIGYVKDIKEKTGAKVVAHVDEKELLNDKNKNLSYTMRCGAQ
                     EFDADIYVNDKDKLELGELKMTFLHTPGHTQGCMCIRVEDEMFTGDTLFAGSIGRTDL
                     YSGDFNQMEKSLKKLCKYEDAVRVYPGHGPTSTLGVEKKTNPYM"
     gene            complement(28878..29327)
                     /locus_tag="KOU88_002684"
     CDS             complement(28878..29327)
                     /locus_tag="KOU88_002684"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003517065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBK3212553.1"
                     /translation="MRAVVQRVSSSKVTVDENTIGQINKGLLVLLGVTHDDKSSDVDY
                     MIDKILNLRIFEDENDKMNLSLMDIGGELLVVSQFTLYGDCRKGRRPGFSNAARPELA
                     NNLYEEFVKKAKDKGVTVGTGQFAAHMMVELTNDGPVTILLDSSKSF"
     gene            complement(29352..31559)
                     /locus_tag="KOU88_002685"
     CDS             complement(29352..31559)
                     /locus_tag="KOU88_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003229747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBK3212554.1"
                     /translation="MHDKELQEIIEKIKVYAPNANFEMVEKAYNLAKKAHEGQYRKSG
                     EPYFIHPLAVANILIEMELDIETITAGLLHDVVEDTEYTYEDIKKEFGKEVADLVDGV
                     TKLGQIKYRSKEETQSENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYMPPEKAKYK
                     AKETLEIYGGIAHRLGISKIKWELEDRALRFMDPEGYYDLVSRVSMKRSQREDYIQGI
                     VELLKDKFKDLSIPCDVYGRPKHFYSIYRKMQKKHKTFEEIFDLTAVRILVDNVKDCY
                     AVLGIVHTLWRPIPGRFKDYIAMPKPNMYQSLHTTVVGPDGEPLEIQIRTHEMHNIAE
                     NGIAAHWKYKEGISSKESKVEEKLQWLRQMMEWEKDLKDPQEFMDALKEDVFNSQVYV
                     FTPKGDVIELPAESTPIDFAYRVHTNVGNKCVGAKIDGRIVPIDYKLQNGNIVEVLTS
                     SNSNGPSRDWLNIVKTPNAKSRIRQFFKKERREENVDRGNTILEREFKKHDIPQKDPL
                     VEKYMALVAKKFNQPSVEDLIATVGYGGIMSSQVVSKVKDLYLKEVKKAKKEQQIQEE
                     DLNKHNISETEYSKKRKKNASQGIIVKGLDNILVRFAKCCNPLPGDEIVGYITKGRGV
                     AIHRADCPNANNNGDFFQNRLVEVSWSSAGKGKFEAEIQIKAIDRRGIVNEITHIVAM
                     DKLSLNGINARKGKDSIVSINLLVEVNDTEELKILMKKLKAIPGVESIYRMTN"
     gene            complement(31633..32145)
                     /locus_tag="KOU88_002686"
     CDS             complement(31633..32145)
                     /locus_tag="KOU88_002686"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBK3212555.1"
                     /translation="MDLKNFIRNIDDFPKPGIDFKDVTTLFKDGDAFKYAVDSIVEEL
                     KDKDVDLVIGPEARGFLMGTPVAYALGVGFVPIRKPGKLPGEVESYEYGLEYGTDTLE
                     IHKDAIKKGQKVAIVDDLLATGGTMEAAAKLVEKLGGEVVSMQFLIELKFLNGREKLS
                     NYDVNSLIKY"
     gene            complement(32158..34608)
                     /gene="recJ"
                     /locus_tag="KOU88_002687"
     CDS             complement(32158..34608)
                     /gene="recJ"
                     /locus_tag="KOU88_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBK3212556.1"
                     /translation="MKKWILKYKGKIEESEFSKKLNISPEICQILKNRGICTEKDSEI
                     FMNPSLDYLRDPFLMKDMQKAVDRIKLAVEKNEKIWIYGDYDVDGVSSTSILCLYFKS
                     IGYNVDYYIPNRLEEGYGINEDAIKLISSRGCDLIISVDCGITSVSEVNTANDLGIDV
                     IITDHHECQSEIPSAFAVINPKQEDCNYPFDSLCGCGVAFKMIQALTPKEEFKTSMYN
                     YLEIVTLATICDIVPLIDENRIIVKNGLKSMKEGKNIGLRELIKVCGVESDKIGSSHI
                     GFAIGPRINASGRLGYSYLGVELFTTQSQEEAVEIASILEEKNNERQMIEAKMYHEAE
                     EMLKSNSRYNDDKVLVLAKEGWQHGIIGIVASKLTEKYYKPTILLGIENGEATGSARS
                     IKGFNIFEALIKCKDLMTKFGGHEQAAGLSLDSDNVEILANEINKFADYNLTEDDMIE
                     NVNVEFELQENVINLNLVEELHKLEPFGLNNPNPRFIVRNYILKDLKVIGKNQQHLKL
                     NIEKEKSYECIGFNMSHLKSMYKVGDKVDVLFQLDENNYMGNRKVQFLLKDIRLARPK
                     SASNDKLSLKLMSKIIPKDTQSLYNISVSDFELFDGNTDINIFDYFEKDTLIISNSIN
                     GFYRAMSDVSLIDLDFNINYNIIEDDSKNTDKLELIFSPNIDKIDLKRYNNIILYDYL
                     YNKGEYSYIYENKREESEIIKYYNKTDLLYLKNVVSNIVPSRDEFITIYKQALIKKEI
                     DLDMVNIRETFNVIPLKFFTILNVFRELNLLDFNLNYEKNSVLIRILPKPQKKLDLNE
                     SLILNNLKNLEKQYNSSY"
     gene            complement(34621..36285)
                     /locus_tag="KOU88_002688"
     CDS             complement(34621..36285)
                     /locus_tag="KOU88_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBK3212557.1"
                     /translation="MRISYRNLKRYREIGYVLIKYGFSFIVERLNIEGIAYKIPLFDP
                     PEEIKNMTTGERMKRVLEELGPTYIKIGQILSTRKDLLDQDIIDEISKLRDDVEKFDS
                     NIAIDIFKEEVGLSIEEIFLEFKEEPIAAASIGQVYEGVLKTGEEVIVKIQRPNIEKI
                     IKSDLEILRTIANTLKDLKKDFNLDLVQMIEEFQTQLMRELDYTFEAINATKFSRIFK
                     NSDEVYIPKVYSEYNTKKILVMEKVNGTKLSDVEKIRRLGYNTKTIVEIGVRSFFTQV
                     LSHGFFHADPHPGNIFVVAKNKIAYIDFGMIGIIDNKTLNQLNEIALAGVEKNVDKII
                     YLLIEMDALNGEADIKGLRQDLLYLIHYYYDISIEKINVTDILNELFRFFRQYKIVMP
                     AQFVTLAKTVITLEGTSRTLNTDFSFGSMGKEFMKHHYKSKFNPKNVVLSSRQNVEEI
                     LLDIKTIPKQLKAILKNIERNNIKMQIEDVKMTRLENCIIELTSQISLSLVLASIIVG
                     SSLIIASPNIENNIWIKFTAIAGFFISFIIGLCLVIRSIRSKYKKD"
     gene            complement(36583..37080)
                     /locus_tag="KOU88_002689"
     CDS             complement(36583..37080)
                     /locus_tag="KOU88_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBK3212558.1"
                     /translation="MIRDYLEDKPLIDESVFVAKSADVIGNVKIGKDSSIWYNAVVRG
                     DEGPITIGENTNIQDCSIVHGDTETIIGNNVTVGHRSIVHGCKISDNVLIGMGSIILD
                     NAEIGEYTLIGAGTLITSNKKFPPGVLIMGSPGKVVRELTEEDKKYIDESYEWYLEAA
                     QNQKY"
     gene            complement(37109..38488)
                     /gene="scfB"
                     /locus_tag="KOU88_002690"
     CDS             complement(37109..38488)
                     /gene="scfB"
                     /locus_tag="KOU88_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioether cross-link-forming SCIFF peptide
                     maturase"
                     /protein_id="HBK3212559.1"
                     /translation="MSMIHKFSMNGYNIVLDVNGGAVHVLDDVAYDLLDFYKEKSKEE
                     ILEILKSKYQEEKINEAYEEILNLEKEGLLYTEDTYQYHPSFVHREPVVKALCLNVAH
                     DCNLKCKYCFAAQGDFGGEKELMSFEVGKAAIDYLIANSGSRKNLEIDFFGGEPLMNF
                     EVVKQLVDYGRSVEKDYNKNIRFTITTNGVLLNDEIIDYINENMHNVVLSLDGRKEVN
                     DNMRPTLNDKGSYDITLPRFKKLVEKRAKDKYYYIRGTFTRDNLDFSKDVMHFADLGF
                     KLTSVEPVVGDESNPYALREEDLPKIFEEYEKFAVEYADRQLQGDGFKFFHFMIDLNQ
                     GPCVIKRITGCGAGNEYLSVTPNGDIYPCHQFVGNEEFKMANIFDEEIVLPENLKNMF
                     REAHVYTKEECKQCWNKFYCSGGCHANAINFNNDISKPYELGCEMQRKRTECSIMIQA
                     KLMLEGATN"
     gene            complement(38793..38939)
                     /locus_tag="KOU88_002691"
     CDS             complement(38793..38939)
                     /locus_tag="KOU88_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HBK3212560.1"
                     /translation="MKKFIVRFMKFASSLALSTAILSANSTCPWIIHQPKVPKEISNL
                     KKTN"
     gene            complement(38969..39547)
                     /locus_tag="KOU88_002692"
     CDS             complement(38969..39547)
                     /locus_tag="KOU88_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBK3212561.1"
                     /translation="MFKRYAEKMTSVLICNNMIDNNESKVYSYGFEILIAFIVNITTM
                     LFIGFLFGKFTYVLFFLMCYCPIRQFSGGYHADNYFRCLLTFIFIILSTILIIENINI
                     DLFKNIIMIIASVSWVGICVLCPIEHRSNPISDREKLVYKKTAIFISTVVLLITILSL
                     SLSIFVDYFTYSAFAMFWIFVMLVLGKLKAKV"
     gene            complement(39915..41345)
                     /locus_tag="KOU88_002693"
     CDS             complement(39915..41345)
                     /locus_tag="KOU88_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4116 domain-containing protein"
                     /protein_id="HBK3212562.1"
                     /translation="MDIKNKIKSIFLPEKNDYLDDEEFEYDIENNEEDLKEDNKVHLN
                     DLSRVKYDYRELKDIENQTEEMCLLAVKQDGTIIEFVKDKTYKVCMEAVKQTYKSLKY
                     ITNQNEDICIEAVKQNYRALYYINNKTENVLIEAIKNASTYDVMEVFKFVEEQTEDVC
                     LAFIERASKNDVAEILKGIKEQTPAICLEAVKKDGKSLAYVKEQSNSICLEAVKENYS
                     ALSCVKEQTEEICIEAVKQNDFALYYVNEQTEKICMEAVKRSYMALQYVNKQTEEICL
                     EAVRIDGRALQYVKEQTEEICLESVRQNGKVLQYVKKQTENICIEAVRGSFEELEIKE
                     ILSYVKIPTERIFVEAVKQNGKILKYVENQTELICLEAVRENYNALAYVKEQTEKICL
                     EAVNQSYEALKYVKEQTEEVCLKAVKQDYRMLKYVNNQTEKICLEAVKQNYRALEFVD
                     NQTEKVCLEAVKQNRKALQYVKQKQS"
BASE COUNT        13706 a         7060 c         4695 g        15941 t
ORIGIN      
        1 attcaattaa cttctttgtg cttgttattt tgttacttct tgttgagcac atttattata
       61 ataacatctt ctcataatat ggtcaactat ttttttcatt ttttttaaat ttattgatta
      121 ttcacccttt gtcatactat tgtgacttta tttttaaaga tataactatt attaatagta
      181 atttccaatt ataataatac tatatgcaat tgtaattaat catataatta ttattatatg
      241 caattattat taatttagaa aggagcttca aaatgtttag aaaagtattg cattatttaa
      301 cactactttc tatttctatt ttttttattg ttggatgttc aaattcacaa aacaatcaaa
      361 acgaaaatca aaataaggaa acacagttac aagaagataa ggaaaaaata gatagtggta
      421 aagatacttc caatgtaata gtttcagacg gaacagataa accatcaaaa gccactacta
      481 ataatgataa taataaatta gatgtatctt ctttagataa cactactctt gattggtttt
      541 atataccaaa caataagcat aaaacaccag aagtaaatac ggacattgaa tttaaatttt
      601 ctgactatga tgccctatac aatggaccta caaaagatgg tcaaaaaaca ctatatctta
      661 catttgatga aggttatgaa aatggataca ctacaaaaat actcgacact ctaaaacaaa
      721 accaggttaa agcagttttt tttgttacag ctccatatat aaaagaaaat aaagatttag
      781 taaaaagaat ggtttctgag ggacatatag ttggaaatca tagtaaaacc catccatcta
      841 tgccaacaaa aacaagcaat ctaaaaaact ttaatgacga attatatgat gttgaaaagt
      901 tatataaaga tgtaactggg aaagatatgg ttaaattttt tagacctcct atgggaaaat
      961 actcagaaaa aagcttggca atgactaaaa atttaggata caagactgta ttttggagtt
     1021 ttgcatacag agactgggat actgataaac aaccatcaca tgaagaagca acgcaaaaaa
     1081 taatggataa tctacatgat ggttctatct tgttactaca tgcagtttcc aaaactagta
     1141 cagaaatttt aaatgatttt atatcaaatg caagaaaact aggatatgaa tttgaactct
     1201 tggagtatta atatttataa ttacatctaa agtctacaaa ctaatatagt taatataata
     1261 taggttataa aataataaat taaaattaga atttttgttt ggtgatagta taggtaaaaa
     1321 cttgtgatag cttatatatg ttggtgggac agggcaataa aacatcaaaa aatttggcaa
     1381 gatattaaat atagataaca gtattttaga tgttatattt agatgttatg tataatataa
     1441 tgaaaaatat tactttatta aagaatacta ataaaaatat caataaaaat agatgtatgg
     1501 cttagaatta gtaaaacaat tataataaat tatagctaca catctatttt taatttatac
     1561 aattaaagat ttattcgatt tattaaataa taaacattgc tactatggtt gttacaacca
     1621 atccggttat aactgggaca aagtttcgct ttgccaattc tattggacta accccacaaa
     1681 ttgccgctgc tgaaataaga ccccaaggaa ctagacagcc tccacctacc catataccac
     1741 tgatttgtcc taatgcagct aatgcaccaa cacttgcatt tatagcagtt ccaaatacag
     1801 aggcaagtga accaactaat gaaatcccag aaaatccaga accatcaagc ccagttattg
     1861 ctcccactac agtttctata cctgatacgg caaatttatt aagtggtatt gtttgagaaa
     1921 gagctatgcc tatatctgat aataaacctt gtgaacctgg tgctaatact tttccaaata
     1981 cacctgtcaa tggtgcaact tcacccatat agaaaaatgc tgctattggt ataattgctc
     2041 caaatatttt tatcccaaac acaaaaccat caattatatt ctcacataca ttttcaagac
     2101 tatctttgcc aaaatttata acatttataa ttattattaa aaatactgct gttccaccca
     2161 aaagagctga tgcatctcct ccttttaggt caaatacata catagcaatt atatcagcaa
     2221 gaaatcccag agctactaaa atagttgcta ttttagattt tccattgaac tcttctactt
     2281 cttcactttc aaaacctttt agttcttctc taaacattcc tttgttaata tctcttttta
     2341 atgtataaaa tgccatagat atggttacga ttcccatcac ccaaaacaaa atcataccat
     2401 catttataac atatgatact gcaacacctg ctgcaccagc tgttatactt ggagctcctt
     2461 gaataacaaa gtctgtagac aaggcaagac catgaccaaa taaatttaat gctactgcaa
     2521 caccaattgc tggtagccca gctctcatag caacaggtaa aaatacagct ccaactaagg
     2581 caacagctgg agttggccag aaaaaccaag aaagaactaa cataacaaat ccagttacaa
     2641 aaaatgctgt attagaattt tttataactc tcgaaaatgg tctcaccata tattgtatag
     2701 cattattggc ttctagggct ttagataatg caaccataat agctataatc aagataattg
     2761 gacccaactc atttaaagat ataataaaag agttaaacac tgctgttata gcaccaaaaa
     2821 tgtttttttc aaagaacaat cccataaaaa aaacacctaa tatacatggt actattgtat
     2881 cctttttcat aatcatagta attaatataa ttaccataaa tagaatgtaa atataatgtg
     2941 ctcctgtcaa aaccatatta ttatgtcccc tttttttaag ataataatat tatatggtct
     3001 tgtaagtaaa cttgttactt gcctagaggt acacaatatt gaacatccca taactaaagt
     3061 cacatgcttc ctgcttcata gaattttaca taagcaatta cacaatatat aatagcaact
     3121 acacaatata taatttaaat ttttatgatt cttttgctgg aatagatatt tcaatagcaa
     3181 attctttatc atctgaattt acatttatgc ttccattatg atatgcaact attttctcac
     3241 aattctttat accaattcca aaactttcta cattcttaga aaaattactt actctatttt
     3301 tttgtataat tagtaattta gaatcctcta ctttaattaa aaatactata ggcttatctt
     3361 tcctagcata ttttattata ttagaacata aattatcaaa tatccttcta aattgtgtaa
     3421 catctacata aatatgatat tggttataaa gttcattttc tattgttata tgaaatcctt
     3481 tctcctccaa tgtatatgaa ctatctaaaa gtaattgaaa aataaattca ttagcattta
     3541 ttttttcata cccttttgaa acttcctctc cagaattaac aaaatgcgta aaaaggtcat
     3601 ctgttaaatc ttttatttga tatgctttag accttacatt ttttatgtat tgttccaatt
     3661 gctcaggact attgtattta tggtctttaa tcaaatctaa ataacaaatt actgacgtta
     3721 atggagttct aacatcatgt gatatcgaag ttactatatc tttattttta ttcttcatct
     3781 ccctttcttt tataagttga ttctccaatg tatgactcat ctcattaata ctagatgcaa
     3841 gtgatgataa ttcatcatta ccttttactg ggattctata ctttaaactg ccactctcta
     3901 ctatctttat acccatttct attttcctta ggtactttat ctttctacta aacaacagta
     3961 aaaatgttat aataaatgta agtgccataa atgtaataga aattgcttct ataaaatttt
     4021 gaaatctaaa tctaaataaa gctactacaa ctatattagc tttaatatca gaaaattgta
     4081 tctcatagtt tctagccatg ggactgctat aaaactcatt ttcctcactc ttatcaggta
     4141 cttcattagg atagtataat gtatcataaa aaaccttatt tcctttatat atcttcatag
     4201 aaacaaacca attatcacta ttccattttg ctatatcatc tccatcatct gctcttatac
     4261 cattgttatt cacataagtt tgaaaattat ccataagttg atttacttct cttttaaaat
     4321 atactttccc ttctgataca tcttttacta tagattcaac agcagagtaa aatggtatat
     4381 ttaaaatgaa agccactgca gctgagatta ctacatatat caatagtata actcccaact
     4441 tagatggctt aattttgtta atcaatataa tacccctttc cccatgcggt ttttatatat
     4501 tgtggatttt tttggtcttt ttctaacttt tttcttaaat ttctaatatg aaccattatt
     4561 gtattatttg ctgtataaaa atactgctca tcccaaatag tttcatataa attttcagac
     4621 gaaaaaactt tttttctatt tttcaacata agaattaata tactatattc tatagttgtc
     4681 aaaaacacag gttctccatt tagtgtaaca tcttgagtat ctaaattgac acataactct
     4741 tttgttttta atatatttgg ctctctttcc ttttcctttc cctggtatat ataataacgt
     4801 ctaagtagag acttaaccct tgaaattagt tcagaatatg aaaaaggctt tgataaatag
     4861 tcatctcctc ctgctgaaaa tccaataact ttatcagagt cttgagtttt tgcagttaaa
     4921 aataatattg gtgctgtcgt tttttctcta atttcattac atgcaacaaa tcctgttttt
     4981 acaggcatta caacatccaa aataatcaaa tcaatcgtac tatctactaa gtttacagct
     5041 tcttctccat tcgttgccat aataacttca taaccttcac cagttaaaag tatttctacg
     5101 atttccctaa tctcaggatt atcatcagct actaaaattt tttttggaat ctctttattc
     5161 atcaccaagc tccttttttt gctatatttc ttaaatattt caaactatat aaaatattat
     5221 actttattag caaaagctta gcaatgtcac acgttttaat agtttctact cctgtaaaca
     5281 tgtttaaagc ttaattaaaa tatacacaca aattgacata ttaataaaaa taatctatat
     5341 aatattatct tacataagca acttttttca ctgcttttac tttttcagaa gattttacat
     5401 gtactactat acatatcaat ccacttatag ctacaaatgc ataaaaactt atccccctac
     5461 taagtaacat tgccggaact aataagtgac cagggaaaaa tatcttaaat aatgtcataa
     5521 aactattttc agaagctcca acagcccctg gcaatggtaa tgaagaaaca gcaatattaa
     5581 gcaaggattg tatcgctaat atctcaaata cagtatatgt tgatagatga aaagctttgt
     5641 atacaaagaa aggaactaaa aacatagctg ttatttgtac aatagttatg actaaaattt
     5701 ggactacaag ttttggattc tgctttatat attgagcacc tttaacatac tcttcaattt
     5761 gagatattat aacttttctt gaactttcaa catcttttat tattcttaac ttacctaata
     5821 aatttgttat tgatattata aaattgttta caagtttttt tgaaaatata attgcaatta
     5881 ctccaatgac aagagcaaca tttgttatta caccatatat tagtaaaatg ttcataccac
     5941 ttacattatt taatataaac tcacgttcca taatgaacat tattccacta tatgccagta
     6001 taactacttg gtgaataaca acaatgacta atagtataag tgaagaatat gatatattta
     6061 tatcgtcttt tttcatataa taaacttgtg ctggttgacc acctgatgct gaaggtgtaa
     6121 tagaactaaa ataaaatcca ataaaagcat atcccataca ttttaaaaga gtagtctttt
     6181 ggtttaaagc tttcatacct aagtatatat ttataccttc acaggcaaca tatataaaca
     6241 tcattgcaaa tccaattagt ataaacatag ggcttgcacc ttttaatgat tttatcaatg
     6301 attcaactga ctgccctcta aaaacaaaat atcctgttat gcccattagt aaaactaaaa
     6361 aagctacact acctaggcat ttatttttct tttcagtttt acttatcata actacatcct
     6421 ttctggtgtt acgaacttta aaccactggc tttaagtttt ggaatagcta tctttaaagc
     6481 ttcaatagta cgctcaggtg cacctactgc accacctgaa ttttcacctg catcatgtaa
     6541 acaaattata gaattttctt ttgttctact cattaacttg tttataataa tgtctactgt
     6601 actatctttc tcccaatctt ctgccattac atcccacaaa gtcattttta gattatattt
     6661 tttaacaaat gaatttgaaa atatattagt atgaccccat ggtggacgat agtagtttac
     6721 atctacacct aaatttttca ttatatttgt actttcaata aaatcttttt taacataatt
     6781 ataactataa agccatgcat ttctgtgttc caatgaatgt aaaccaacta tatgattttc
     6841 tctcaacatt ctttttataa tttcaggctc tttttcagca ttctttgcta ctacaaaaaa
     6901 catagcttgt atatcatttt cttttaacac atctagtaat ttttctgtat atctcttatc
     6961 tggaccatca tcaaatgtaa gtgcaatttc attttctcca gccatatttt ttaatacctc
     7021 tttatttaat agtttattat agtatgtagg tataattgaa tggactaaaa aaatcaatgc
     7081 aacaacgata attaaaccta ctacatacat tctctacacg ctccttgttc atcaagtgaa
     7141 aataaaatat tctctaaggt attattatca aattgttttt ttaattcttt catgttactg
     7201 ctcatttctt taagagtagc atcatcataa attaaatctt ttatctcatc tacatagtat
     7261 tttttatttt taccaagtat tctcccaatt tcattattta atataaaact agcattatct
     7321 atctcttgtt gtaaaaatgg attaaatgcc aatattggaa gttctgaata aattgtttca
     7381 aatagtgtta ttccacctgg tttagaaata ataaggtcag aatctttcat atatttatat
     7441 acttcattgg tgtaacctac tacctctata ttttcatatc taccatatag tttatagtac
     7501 atttttttat tattaccagt tattacagta gtttttactc cttctaaact atttaattct
     7561 ttgtaaaatt gttctgattt aggcagtaat cctaatcctc cacccattat aagaatattt
     7621 tttttagttg aatgatttac atgttctatt cttttaaatt ctttttttac tggaatacca
     7681 ttaactttaa tcttagattc atctattcct ttaaaaacaa gttcttcctt agtagattta
     7741 ctagctacta aataacagtc tgtattttta ctaatccatt ctgagtgact acttatatca
     7801 gttatacatg ttattaaagg aagatttgag ttatattttt ccttatatct tgatactaat
     7861 tgagaacaaa atggaaaagt tgaaataact actgttggtt gtacttcatg aagtaatgta
     7921 tctaatttat ttaaaaaata atctgaaaaa gtaaatttta tatctttctt tccattttca
     7981 gcacatttat aaaataaatt ataaagacta cttccccgat ttacaagaat agaaaaagtc
     8041 ttgtacattt tatctgaata gttaggcata atgtactcaa atatatcttt aattattatt
     8101 tctgaattat caaattttgc ttttatatct tcacttaaag aatttgatgc tgagtaatga
     8161 cccataccaa attttcctgt aagaattaat accttcataa gattccctcc tcgttaaagc
     8221 ttttcttttc atatgattac tatacttata agtatagact ttaaatcttt agaaaaacct
     8281 agtataattc ttaagaaatc ttaaagtttt aattaaaaaa tacaaagaga ccatctaaaa
     8341 atagagataa ccatattttt tattatttaa ataatacaaa tatgttcgat tccatacaaa
     8401 aaagtgcctc ataaactaaa aagttcattt tgagacacct tttttatatc taaatatatt
     8461 caaatacata cacaatcatt gtaattattt aaatgtattt tatttagttg ttctttataa
     8521 ttaatccata atattatatt cttcatataa aggatatttt tcagttaaac caacaaccaa
     8581 tgttctagcc ttagattctt catcataagt taaacatagg tctatagcct cagcgattat
     8641 tgccatatct tcttctttca tacctctagt agttacagct ggagtaccaa gtcttattcc
     8701 acttgtaaca agagcaccat ttgggtcaaa tggaattgta tttttattag ctgttatata
     8761 agcatcatcc aatctctttt ctgctgcttt accagttata tttttattag tcaaatctaa
     8821 tagtattaaa tgattatctg tacctccaga aatcaattta aaatctcttt taataagttc
     8881 ttcagctaag gcttttgcat ttttagcaac ttgtacctga tattctttaa actcatcact
     8941 taaagcttct ttaaagcaaa ctgccttaga agcaattata tgttcaagag gtccaccttg
     9001 aataccaggg aatattgctt tgtctatgtc tttagcatat ttttctttac aaagaataac
     9061 acccccacga ggtcctctta aagttttgtg agttgttgtt gtaacaaaat cagccacttc
     9121 acatggattt tggtgaagac cagcagccac aagacctgct atatgagcca tatctaccat
     9181 aagcaatgct ccaacctcat cagctatctc tctaaacttt ttaaaatcta tttctctagg
     9241 atatgcactt gctcctgcaa ctatcatttt aggttttact tcatgtgcta tctttctaac
     9301 ttcatcaaaa tctataagtc cactgtcttt atctatacca tattcataaa atttataata
     9361 ttgaccagaa atattaactg gagcaccatg agttaaatgt ccaccttgag ataaattcat
     9421 tcccataaca acatcacctg gttttaacat agcaaaatat acaccaatat ttgcatttgc
     9481 tccagagtga ggttgaacat tagcatgttc tgctccaaat atttttttga ttctatctat
     9541 tgcaagagtt tcaacttcat ctatgtattc acatccacca taatatcttt tgcctgagta
     9601 accttctgca tacttatttg taagatgact tcccatagtt tccattactg gaactgatac
     9661 tatgttttca gatgctatta attcaatatt tctttgttgt ctttttaact ctcttttcat
     9721 actttcataa atctcagggt ccgctttttt caagttctca aacatattac tcctcctagt
     9781 tattatttaa attttatttt tacagacatt tcataatttt cgtttttatc aatatgataa
     9841 tttattatta tagtccttta ccaattaata gtcaagtgtt ttgccatttt tccatattta
     9901 acatagttac tttctttatt tttaagttaa aatataataa ataatattgt ctaattcttt
     9961 taattggata taatttaaat gtgactattt tgaaacaaaa aaaagataat atatttatat
    10021 agatattaag gaatattact taaaaatttg atataatttc aatattacgt tttttaattt
    10081 ggaggtgtat ttatgaatca aaatgaggaa cttgaatata agaaaaatat tctaaaacta
    10141 gctctatttg taggggaact gatgataaaa aatggagctg aaacatctag ggttgaagac
    10201 agtgtcctta gaatatgcag gtcaagaggg ttttatcatg taaatatttt tacaactcct
    10261 acagtaataa ttatttcaga tgagaaattt gatggctttt cgtttatgaa aacgattcaa
    10321 tcaagaggta taaacttaaa taagatttct ttattaaaca gtttttctcg agaatttgtt
    10381 agtgacaaag agtatgatat tgataatgcc attgcacgtc tttatgaaat ccaagatgta
    10441 aaaccttatc ctttatggtt attttactct tgtacaggaa ttgcatctgc ttgttttgct
    10501 tgtttgcttg gagggaatta tgtattaaat tttatactta cgtttataat agcaatcttt
    10561 gctgcaatta cttatgataa aacgatgaag ataagtgcaa tatctgcatt ttcctgttta
    10621 gtatcttctt ttttaattgc actttcagga gttctactag ttgaaatagg cattttagat
    10681 gaccctaaaa tgcttatagt cggcgctata atgccactac tcccaggagt tgcttttata
    10741 aaagctatta gagatttaat atcagggaat ttaatatcag gaatttctcg tgcttttgat
    10801 gctgctatga ttattattgc aattgcttct ggagttggtt ttgtccttga tacatggtat
    10861 agaataggag gtcctttcta atgactgata tgtctatgat tttgcatttt ttattttcag
    10921 gtgttgcaac tgctggattt gctgttttct ttaatgctcc actatatcta cttcttccag
    10981 ctggagtaac tggcggaatt ggttggattg tatatgttta tttatttaat tttactacaa
    11041 atgcagtttt tgcaggtttt atcgctgctg ctttggtctc agcgtgcagt gagactttag
    11101 caagaaaact aaagcaacca gctattgtgt tcgtaattcc aggtattctt cctctaatac
    11161 caggaattgg gctatataat acaatgttgt ctttgattca gaaaaattat tctttggcta
    11221 tgtcaaaagg tacagatgct ctatttctaa gtgctgcaat agcacttggt gtattagttg
    11281 taacttcttt tgtaagaaca ttgaatcttt taaaaatcag aaaaaacttt attccttaca
    11341 gaaaatcaaa ataaaaatat aaaaatagca atgtacttaa actctacaaa tacgtattga
    11401 gtatttattt aaaaagtaca ttgctatttt ttaattataa ttatcttaaa ggtcaattaa
    11461 tattcttgtt attactggta taaattctct actgtctcta aattttttgt cattcttctt
    11521 taagtataaa taacagatta ttgtaagaca aattccaact aatccactta tggcttcaac
    11581 tccagttgtc attccaattg cccccaatat ataataagtc cctattgttc ctacaagaag
    11641 tgctataaga ggtattatat aagccattac agctgctttt aatacattca tattatccat
    11701 actcacttct acatggtcac caacttttgc accaattgtg ttgtctactt ctactaatat
    11761 ttcttttgac tctgctgaat ttgtagtagc acattttcca caagcagcac aagctgaatg
    11821 tctttgcatt tttaactttg cagttctatc atcaacaatt tccataataa atccttgttg
    11881 attcataact aaccgcctcc ttattttgta aatttattta tagtatccat aagctctttt
    11941 atcatctctt cagttttatc agcatcatca tgtttaatgc tttctgctac acatcctttt
    12001 atatgattct ctaagataat tgtgcctact ctatttatag cagaccttat agcagatatt
    12061 tgaaccaata tatcaacaca ataacgttct tgttccacca tcttttgtat acccttaact
    12121 tgaccttcta ttctttttaa tctttttatg agagcttccc tctcattgtt tggtgctaat
    12181 tttctttctt ccataaactc acctcatact ctaatgatgt cttatacaat tatgctctac
    12241 ttaccaactt gtttaaaata taatacagtt attattacta taaatgccaa aattgatatt
    12301 gcaatagacc tactttgatt cttagtttgt tccatactta actttccatt catcttaaat
    12361 cctgccaatg ggaataaaaa tataaccagt gcatcaattc caagtacaac ttgggctgca
    12421 atagtccatt tactcaaaaa gcagaatatt ccgcccacac ctaaaagaac ctctaatata
    12481 tttataaact tatatgtagg tttttttgct atatattctt caattttttc cttacattct
    12541 gcacgacatg gatatatatt catattgtca tcatatttta tagctaattt attatttggt
    12601 gactttatat ccctattaca gtaaagacat tttttcattt tatattctcc tctagtcttc
    12661 cttaaaaaat tttgcctaaa ttattatacg ctctaatact attataccaa atagatacaa
    12721 aaaacaaaaa taaaaggaat aattttagct acttctttta cttcaatgtg tagtctataa
    12781 taaatttata ataataatta aataatatta tttaatctaa tttaattatt atgtaatcta
    12841 aaataagtca aatttgtatg agaggttaaa atgaaacaaa tggaattagc tattgtaagt
    12901 ttaaaaaaag acgctggaga aatttatgaa aatcaaataa gacaattctt aggtgataat
    12961 ctaaagataa atttatactc atttgaagag ggaaatttaa agttttttaa agaaaaactt
    13021 atactcctat ctgcttattt aaaatatgat gaaatagtaa aattatctca ctatgatgct
    13081 caaatcattg ttcccaagtt gacatttgaa aagaacagta ttgatatgat atccaaatta
    13141 gaaaaagata aaattattta tgtatataac ttaagtaaag atatggcaat agaaacaatt
    13201 tctttaatac atagattagg aatagacaat ataaatatcc tgccctgcta tccagagatt
    13261 gagtttactc ccacagatgc tgtaatccta actcctggcg aaaaaatctt gcctaagttt
    13321 aaaaattgtg aagttataga tttaaaatac agaataatag atttaagttg tattgttgaa
    13381 attgctacaa aaaccaaatt aaaacatcta ataaaagatg acctaataaa aaaatacgta
    13441 gaaaaaataa ttcctacaag ttatagtaca ggtgagttat tgttagatgc aaataagttt
    13501 gaaagacaat ttgatttgtt gctatctata attgatgatg gaattatatg cacaaataac
    13561 gatggaataa ttcaattcta taatcatatg gctagaaaaa ttttgtctat aaatgcaaat
    13621 gaaatgattg actcatttgt tggtgattgc ataaaagaca tcaattttca aagcatattg
    13681 accaataaaa ctccattttt tgagaaattg attaaaataa atcatattga tataaattta
    13741 gagattaaac atatacaatt aaatgtattt gatggattta tactaaagat gacaaagttt
    13801 tctcaattag aaaaaaagca agctaaatta agagcacaac tagtaaactc tggtaatatc
    13861 agtaaataca catttgatga tatattaggt tctagtatac aaactattaa tacaaaaaaa
    13921 attgctaata aaatggctca atcaaattca tctatcctta taattggtga aagtggtact
    13981 ggtaaagaat tatttgctca atccattcat agtgcttcta ggagaaaaga tggtcctttt
    14041 gtcgcagtaa attgtagtac ttttcaagaa aatctactgc aaagtgaatt atttggctat
    14101 gatgaagggg cttttactgg tgctaaaaaa ggtgggaaaa ttggtttatt tgaattagcc
    14161 aacaatggaa ctatattttt agacgaaatt ggagaaatgg atttaaattc tcaatctaaa
    14221 ttacttagag tcatacaaga aaaacaagta cgacgtattg gttctaataa tgtcattgat
    14281 attgatgtaa gaataattgc agctactaat agaaatttaa aagaacttgt atctaaaaat
    14341 atgtttagaa gagatttata ttttaggttg aatgttcttc cccttaaaat acatccactt
    14401 agggaaagac ctgctgatat atttgaaatt tttggttcat taaaatatga tattccatgt
    14461 aattttattc taagtgagga agtaaaagaa atctttaaaa tgtatagatg ggaaggaaat
    14521 gtaagagaat taagaaactt aggagaatac ttctgttact tggaaaaaga tattatagaa
    14581 atatgtgatt tacctgaata tatattggat actatagatt caaattatag tagaaccgtt
    14641 tgtaataaag taagtgataa tataaaaaag tatcaattca acattggcaa agacaaaaac
    14701 atcatgaaat acgactataa ttttaaaaag tcactagatg aatacatatt tatattggat
    14761 aatttaaaaa aggcttatga tttaaaagaa agaataggta gaaaaagctt atgtaaaata
    14821 gctttagagg aaaatagatt tttgacagaa caacagatta gaaatatgct tttagaacta
    14881 caagactttg ggcttgtaga catacttgtt ggtcgtggag gttcaattat aacatcaaaa
    14941 ggagtagaat ttctaaaaaa tataaatagg tctaacaagt taaacagtta aacctattta
    15001 acctatttaa ttacattttc atatatttaa aaatttatta gaaataacct tttccacaaa
    15061 gttttaagta taattaatat ttttatctta tctatgctct gaaattactt aatattaaat
    15121 attaacttgt gaataaatat tttttattat caatattggc acgttgtttg cttaatatta
    15181 ttaacataaa attaaaatta ctggaggtat ttacaatgaa ttataatttt aatgagattg
    15241 ttgatagaag caataatttt tcatctaaat ggtcagaaat ggaaaaaaag tatggaacta
    15301 atgatttact tcctatgtgg gtggctgaca tggattttaa ggctgcacct tgtataattg
    15361 attctttaaa aaatagacta gaacaagaga tttatggcta cacaacaaga ccagattctt
    15421 acaatgaatc tatagtaaac tggctagata ggagacataa ctggaaaata aaaagtgagt
    15481 ggttaattta tagtccaggt gttatcccag ctataagtct tttaataaat gaactcacaa
    15541 aagcaaatga taaaataatg atacaagaac cagtttacag cccttttaat agtgttgtaa
    15601 aaaataacaa tagagaacta attataagcc cattacaaaa actagaaaat ggaaactaca
    15661 taatggatta tgaagacatt gaaaacaaga ttaaagatgt aaaattattc atactttgta
    15721 atcctcataa tccagttggt agagtatgga caaaagatga attaaaaaaa ctaggagata
    15781 tttgtcttaa gcataatgta aaaatcatat ctgatgaaat acatagtgac attatattaa
    15841 aaaaacataa gcatattcct atggcatcta tttctaaaga atttgaaaaa aatacaatta
    15901 cttgtatggc tccaactaaa acttttaata tagctggtct tcaatcatca tatgtagtac
    15961 tacctgatga aaaagactat aaattgttag atgatgcctt taccagaatt gatataaaga
    16021 gaaataattg ctttagctta gttgcaactg aagcttcata taataatggt gaatcttggc
    16081 tagaatcatt tttagaatat ttagaatcta atatagattt tgctataaaa tatataaatg
    16141 aaaatatgcc aaaacttaaa gttagaaaac cagaaggtac ttatttatta tgggtagact
    16201 ttagtgcact tggattaagt gatgaggaac tagaaagtat acttgtacaa aaaggtaaag
    16261 ttgctctaaa tcaaggaaac agctttggca ttggaggaag tgggtatcaa agaataaact
    16321 tagcttgtcc aagaagtatg cttgaagaag ctcttataag aataaaaaat gcaattaact
    16381 aaaaatattt aaggagaatt tgcactatga aaatgaatac agaaagaaaa ataccttcat
    16441 ttagatattc cttgttagta atgcttgcaa taatagccct aacatcagtt ggtatagttg
    16501 tatttaatgc ttctataact acaatgtttt tactttcatg gcttatagta gttcctgcag
    16561 ccatgaaact tggttatact aatgatgaaa tagaagcttt tggatttgaa gttggtaaag
    16621 atgcctttca atcaaactta attatacttt ctgttggtgt actaatagca gcttggatag
    16681 ctgctggtac aataccaaca gtagtatata gtggactaac aataataacc cctaaatatt
    16741 ttctgcttac aacattaatc gtatgttcat taacttctgt tgctactggt acatcttggg
    16801 ggactcttgg aacttctggt atagcaatga tgagtattgg tactagtatg ggtattcctc
    16861 ttggtttaac agctggtgca gtcatttctg gtgctttctt tggagataag atgtcacctc
    16921 tatcagattc tacaaactta gctgcagcag tttgtaagac agatgtaatt acacatatga
    16981 agcatatgtt ttataccaca ggacctgcat acgtaatatg tatagttctg tatacagtaa
    17041 ttggatttaa gtattcaaat aatactatag actatgttca aataaatcaa atcaaggatg
    17101 tattaaattc aaactttcat attggtttag tagcaatgat tccaataata tttttattat
    17161 tacttttatt gctacaaaag ccacccatta tatctatact aagttcagct atcatgggac
    17221 ttattatagc agtatttcaa gaaggagaaa aaataggtga tgttttaaat tacatgctat
    17281 caggatttac tatagatact ggatttgtct atgccgacaa actattaaat cgtggtggaa
    17341 taatgagtat ggctgaaacc gttttactag tatttgtagt tttcgttatt gctggtattc
    17401 tccaaaaaac tggattctta gaagtactgc ttcaacctct tataactaaa ataggaaaat
    17461 caagaactaa attggttggg tctactttta tagtaagcta ctttgcaaat gcatttagtt
    17521 catcaatgat gttcacttct gtatttgtcg gaactctaat gtctccaata tacaaagaat
    17581 ttaaattaaa accacaaaat ctatctagaa ttatagaaga tacagctaca cttggtggtc
    17641 cattaatacc atggaattca aatgctgttt tctgtgctca gactcttggt gtaagtccac
    17701 tagaatttat tccatattgt ttcttaagtt ggattacacc tataatttca tttatttatg
    17761 gtgtaactgg ttttactatg cttacataca cagatgatga aattgaagag ttagaaatat
    17821 ttgatactgc tcagagaaga gttgattgaa tatgaaattt gaatactatt acttaattca
    17881 ggatattgca ggtatattat tggcatttat aggacttaga atgtccatta ttggatttag
    17941 gatactttct atgagggggc tttctataaa tacactttta attgtaatta aatactgctt
    18001 atttaccata gcaggactga atttattaat atctaaattt ggaattagac actggatttg
    18061 gagtgtttgt atgttgataa tatccataat aataaatccc agaattaagg tatcaaaata
    18121 gaaatagtta ttagacttaa atttttataa aaaaactgct ttacaaatta aagcagtttt
    18181 tttattgtta cttataatta aataactggt gtatcagata agtaatcatt acttacataa
    18241 ccatatccac cattatactt tatttttacc catccagtag caaacatttc tattgtttct
    18301 actttgcttc catatgaaag gtgacctatc ttttcatctt ctgtacttgg tcctttccta
    18361 acatttagac catctttttc ttttacatac tttattttta tattttcatt actattatca
    18421 ggcttattat ttgtcaaata agacccacta acatatccaa taccttcatt gtattttatt
    18481 tttacccatc cagtttttaa cacatctaaa acttctactt catcaccatt atttagatat
    18541 cctataacag aagcttctat tgtagcatca tttcttatat ttaccttatc tgtattagtt
    18601 acatacatta ctctcttatt gttactattt gcctgtaaat cttttaattc tttaaatgca
    18661 ttttcatttc ctccactacc aacttgagtt atagaggtag catttttatt cgaaaataca
    18721 ctcttttgtg ttgcacttaa ttgttctcct acgattagta caggagaatt ttcttttgat
    18781 gctagtacac ctactgctag agcgtctata agttgatttt gatttttcat tccatcctta
    18841 gccacaaata cattgtttaa tttattagat gtataaaact tttctattac tttaccatta
    18901 gtttcatttc tatctgctcc acctattctt tctgaattag gtaaactttg ttttatttta
    18961 tctgatacag cattagtaga gcctattatg tatgatttat ttatattctt agattctata
    19021 aaatctttaa agctagatat accagatgca tcagatactg gaagtataac cattccatta
    19081 gtagcagcta cagaagctat actaactgca tctgcaagac ctgtgtaccc atttactaca
    19141 gctatttctg atatatcttt taatccttct atttttttag ctatactcaa agctgtttgg
    19201 tatctatcac taccaccaac tctatcagta gttaaattat tagattctaa ctgtttttgc
    19261 acatcatttg atacagaact agatagacca attatataaa cttttttaac tcctaatctt
    19321 tttaattctt tctcagtttg tgaatttaga ttattttttt ctgtcaataa tataggagca
    19381 ttttttaatt tagcaaatgg tgttacagct aatgcatcta caatagattc actatttaca
    19441 actacagcct catttgcact actccatcct tttttactta cttcaacagc agtttgatac
    19501 ctatcctgac ctactaaagt attctcaact gttgttctac ttatttcatt tgcatatgct
    19561 actggtgata agcttaaaac tagagataag cacagcattg atgatattga tttagttaat
    19621 ttcatcttga ctccccctaa aattatagta tctaaatgtt tcctatttaa aatagtataa
    19681 cataataatt taagtaacat cattattata aaatattatt tttcttatct aataagcttt
    19741 tattcttact tgacattaat actttgctca tcaaatgaat tttttatata actaaagttt
    19801 gtaacaatat ttccttagtt aatcatttaa agttactttt tttaattaga ttatgtacaa
    19861 aatataaata acaatttaaa taacttttta atatattgta gtttattata taaactttat
    19921 attataatgt ataatgtgga gttgattata aaattgatat aactcaagtc atattaaaag
    19981 aggtgtattt tatactatgg atttattgca tcttaagtat tttcaaactg ttgctagaat
    20041 ggagcacata acaaaagcat cacacaagtt aaatatagca cagccagctt taagcaaaac
    20101 tatatcttcc ttagaaaaag aacttggagt tcagttattt gacagaaaag gaagatatat
    20161 tgttttaaat gagtatggaa gattgtttct aaaaagagta gatagcattt tagatttagt
    20221 agaaagttca aaaaaggagt tacaagacac ttctttagaa aattcaggag aagtaaagat
    20281 attatctcct gcagcggcta atgtgttacc atcacttttg agtaatttca gaaaactata
    20341 tcccaatatt acttttaatg tgtcacatac tttgccatca tcttataaaa aaagtgattt
    20401 tgatttgtac atatcttctt catttacaaa gctaaactca gaaaatagca taactttaac
    20461 atgcgaagaa atactattag gagtttcaat aaaccatcct ttatcattaa aggatgaagt
    20521 atatctaagc gaagtttcag atgaaaactt tatagttata acgaagggtg agaattatag
    20581 agaggtaatt gatatcctgt gcgaatcagc taatttcaaa cccaaaatag catttgagtc
    20641 tgattcacca tatacaattt atgctcttat aaaatcactt caaggagttg gatttatatg
    20701 tggaaaatca tggggattat ctcaagaccc tgagattaag ttgttacata tcaaagatat
    20761 tgaatttaaa agatatttaa atctttcatg gtttagcgaa aactatgaat ctaaagctgt
    20821 gttgttgttc aaaaactttc ttatcaacta ttttaaaaat atttaaatca aagttgataa
    20881 tattaaagag gatatatcaa agtataataa atttaatctt aatattgata catcctcttt
    20941 ttatcatttt atattgaact tgtattatag tatagaatta tatgttatag ctactttttc
    21001 tgtctttcaa ataggggata tcttccctat acttttttat ttcatctaaa tcaatctctg
    21061 ataatacata tttttccctg tatgtatcta attgagttat tacagtacct ctaggattgc
    21121 atattttact ctttccaaat agtattaaat tagagtcatt acttactaaa tttacaccta
    21181 ctgtatatac agtgttctct aaagctcttt gagatacatt taaatcccac atatcttcat
    21241 cttgtattct ccatgcagat ggtataaata ttatttcaga accttttaat gtcaattctc
    21301 tggatacttc tggaaaacct gcatcataac atatcattac accaaatcta ccaaaatcag
    21361 catcatatac ctctactttt tcccctcctt taaagtatac tgcttctaat gaccacagat
    21421 gatttttaca gtattctccc ataatcttac cttttctatc aaatataact gctgaattat
    21481 aaacatgtgt agaccctttt tctaaggttc catatggaga tatcaggtat acattatttc
    21541 ttttagcagc ttctgacatt gattcctcta tgtacttatt atgttctctt attaattcta
    21601 atgttttaac tccacctaaa gactctaaat tatatcctgt agcaaatagt tctggtaaac
    21661 aaattatatc tgccccttgt tttcctaagt catctatcat ctctactgct ttttctatat
    21721 tttttttaac atttccaagt acactgtgtt gttgaattat acctattttc accttacgac
    21781 ccatgtaatt gcccccttta tttatctttg attccaaaac aattcattaa tatataataa
    21841 ataaccatac tcactacaat tccatttatc ggaggtatta agaaatttat ttttgaacta
    21901 taatacgacg ctgcaaaacc tattaaccaa cttattactg caatccaatt tattccttct
    21961 ctatgcttat aagttcttcc ttgtataaaa taatactcac accacataat tcctgctatt
    22021 gcaggaactg cgattcccaa gaaagataaa aatgactgaa atttaaatat tataccagta
    22081 gctgctatta ttgtacctat tagacctgca actaaagtca aaacatttct ttttacattt
    22141 ggaaaaatag tttttaatgc taatccacca gaataagcat ttgatacgtt tgtagaccaa
    22201 gatgcaagta ttaaaataac aaacgctacc catccaaaac ctaaattagc caatacttct
    22261 gttatatccc aagtaggtgc tcccatagac attacaccag ctgcaacttg ttggaataat
    22321 gaaataatcc ctagacctaa aaaactgata atccaaatat cttttactcg tctcgtatat
    22381 cttaactgat caggtgatat aattgcacca actataacaa gacctactac aatattaaga
    22441 ccttcaacca tactcatagt tgtttgagga gtataattat aaatagcttc aactccataa
    22501 gtagaaaaag ctttaaaaac tccccacacc attaatatca taagtggtgg tataactaag
    22561 taattaaatt tagccatagc tttaaagcca tatagtgcaa aaacaaccat aaataatcca
    22621 agtataactg taactaatgt taggtttaca cttgggaata tcttttgtac tgatagtcct
    22681 gcaacccctg cttgtacacc aaaccatcca aaactagtta taccaagtaa tagagatata
    22741 agatactttc ctcctatctc tccaaatgcc cccttagcta atacatatgt atttaaccct
    22801 tctttgtaac ctatataacc ttgtatcata ataattgcaa ctaatattaa gttccctata
    22861 attgatgtaa taatcatatt agaaagagtc attcctaaaa ttaaagttcc cccaaccatt
    22921 agttcagata tagctatgtt agaaccaagc atattaaaca atggagctaa ccatccaact
    22981 ctttcctctt ttggaactgg atttaaaact aattcttctc tctcttgcaa tattatccct
    23041 ccctttcttt ataaaagaat aatttctact tttttctact tttttttcac tattaataga
    23101 atttttcttt atataattgt aattctattc tacaaaaaag tataatatct agtttgttat
    23161 caatttgata taatttaagt tataaataga taaatagtcc aaatttatta ttttaattta
    23221 atctattaag tcatatatta gacttatttc aaatttgtta tatattcttt aattaaaatc
    23281 gtgtactcat tacagaagta gtttctaaaa caaccaagtt tatgtaaaat ttttaaacat
    23341 agtattttaa ttatattggc tgagaataca aagataattt atgaaaatat atagagaaaa
    23401 aatataaaat aattctaata aaaaaagtct gaatataaat atactttata tccagacttt
    23461 ttacatttta atttcttgca actacatatt attcattatc ttttatatca acttttatac
    23521 ttaattcttc taattgctca tcttccgcca atgtaggagc atttgtcata gggcaaacag
    23581 cattttgatt tttagggaat gcaataactt ctcttatatt atcagttcct gcaagtaaca
    23641 taacaagtct atcaagacca aaagctagac cagcatgagg aggagtacca tatttaaatg
    23701 cttctaataa ataaccaaac ttttcattag ctctttcctc tgtaaaacca agtgctttaa
    23761 acattcttga ttgaacatca gaatttgata ttctaacact tcctccacct atttcataac
    23821 cattcaatac aatatcataa gctttcgctc ttaaagatga cttatcacct tcttctaact
    23881 tgtctaaatc ttcatccata ggtgatgtaa atgggtgatg cattgctgag aatgtgcctg
    23941 tttcttcatc ttcttcaaaa actgggaact cagttaccca tagtaagtta tatacatttt
    24001 tatccaatag attaagccta tttgctactt caagtctaac ttgtcctaaa gcatcaaata
    24061 ctattgagtt tttatcagct acaaataaaa gtaaatctcc tacttcagca ttcattcttg
    24121 taagtatagc gttcatttct tcttcattga agaattttgc tattggagaa gttactcctt
    24181 cttgtcctac tttcatccaa gcaagacctt ttgctctata tgtcttagca tgttcttcta
    24241 gtgatgatat ttgttttcta gtaaagtcgt cagctttgcc ttttacgttt atacctctaa
    24301 cactttttcc tggttgtgta gcatcagcaa acactttaaa tccacagtta caaacaacat
    24361 cagatatatc tgttaactca tatccaaatc tagtatctgg tttatctgaa ccatatttag
    24421 acatagcttc tgcataagtc atcttaggaa gtggaagtgc caattctaca tctaaaactt
    24481 ctttaaatat cgcttcaagc aaaccttcaa tcatactcat aacatcttct tgctcaacaa
    24541 aagacatttc gcagtctatt tgtgtaaact ctggttgtct atctgctctt aagtcttcat
    24601 ctctaaagca tttaactatt tggaaatatc tatccatacc acttaccatc aataattgtt
    24661 tatataattg tggtgattgt ggtaatgcgt aaaattttcc tggattaact ctacttggta
    24721 ctagataatc tcttgctcct tctggtgttg gagctattaa aaatggtgtt tctatttcgc
    24781 aaaatctatt gtttgataag taatttcttg taatattcat tactttatgt cttaatttta
    24841 aatttctttg catagatggt tttcttaaat ctaagtatct atattttaat cttagtgctt
    24901 cagaaacatc atcatcatct tttatataaa taggcgaagt ttctgacttg tttaaaagtc
    24961 taagttcagt tgcaaatatt tctatatcac cagttggcat attagggttt ttagattgtc
    25021 tttcgcatac ttttcctttt acagctatta caaattcagc ccctaatttt tcagcttttt
    25081 caaaagcttc tttatctaca tctgtatcaa aaactatttg acataatcca cttgtatctc
    25141 ttaaatcaac aaatacaaga ccacctaaat ttcttttttt ctgtacccat cccataagta
    25201 caacttcttc atttatgttt ttttctctca actctccaca gtagtgagtt ctctttaaac
    25261 cctttaaagt ttccaagata ctacctccat tttatctaat tttaatgcta tatatttatc
    25321 taatacacaa aacatcatac tttcttattt tacagctttt gctttaattc ttcaactaat
    25381 gtacttaatt ttacagtagt ttgctctgat gttttcatat tttttaatgt cgcagtgtca
    25441 tttttaagtt catcatctcc aattactatt gtaaattttg aatttatttt atctgaatat
    25501 ttaaattgtg ctttaacact tctctctata tggtctttat ctgcacttat atgattttgt
    25561 ctcaagtctt ttaacaattt aaagcttctt gtatttgctt tttcacctat agttactata
    25621 aatatatccg tagattgagg gttttctatt tcaattccat taccttcaag tgtaagtaaa
    25681 agtctttcaa ttcctagtcc aaacccaatt ccacttatac cttttggtcc tcctaattgt
    25741 tcaacaagac catcatatct tcctccacca catacagtac tttgagctcc tatatcatta
    25801 gatataattt caaaagcagt ttttctatag taatctaagc ctctaactat tgttttatca
    25861 attacaaagt ttatattcat ttcctttaag tattcttgaa gtttatcaaa gtgagattta
    25921 caatcatcac acaaatggtc tgcaataaat ggtatatctt tgatattttc tttacatgta
    25981 ggatttttac agtctataac cctcattgga tttttttctc ttctctcatt gcaagtatca
    26041 cacaatatat cagcttttga gtcaagatac tcttttaata aagcattgta ctcttttcta
    26101 caaactggac aaccaacaga atttatactc actaccaaat catttaatcc aacttcatta
    26161 aaaaattgaa cagctagtgc gattatttca gcatccattg aaggagtatc acttccaagt
    26221 gcttctattc caaattggtg aaattgtctt tgtctaccag cttgtggtct ttcatatcta
    26281 aaacaaggtg tcacataaaa taattttgtt ggttgagtat ctgcatataa tttattttct
    26341 ataaatgctc ttactacacc tgctgtacct tctggcttta gggtaatttc tctatcacct
    26401 ttatctttaa aagaatacat ttctttttga actatatctg tagtatctcc aacacttctc
    26461 ttgaaaagtt ctgtatgttc aaatataggt gttaccattt cttcatatcc atataaagca
    26521 catatttctc taaatttatt ttctacataa cgccatttgt aagcctcttt tggagttatg
    26581 tctttagttc ctctaggagc tttagtcaac atttttatat acctcttctt tcttcctttt
    26641 tatcatttca tctactcttt caatgtattg ttcaacattt tttacatttt ctactctttc
    26701 aattctatct tcatctacat aaacaaattt cgatatagca cctgcaccta atgcatagtt
    26761 actttgtttt tcttccataa tctgtatatt ataaatgcac tcatatcctt ctttagcata
    26821 acctatattt tctaaatttc ccaacatatg tttttgtctg tacatataat atggatttaa
    26881 tcccatatct tttgcatatt tcattgataa atctatcatt tttaccattt cttcatattg
    26941 tgttagatgt tctttatacc tatccatatt tatatttaag ttggatgctc tctttatggc
    27001 taatgtatga actgtaaggc tttcaggaga aagttttttt atctcctcca atgtgttctt
    27061 taccatattt aagtcttcat ctataagacc taaaattata tccatattta tattatcaaa
    27121 tcccattcta cgagccatat taaagcaatc tactaaatca gatactctat gctctcttcc
    27181 aatctttact aaagtatcat cattcatagt ttgaggattt atactaattc tactaacatt
    27241 gtgttttttt aacactctta gtttttgttc tgtaatagtg tcaggtctac ctgcttctac
    27301 agtaaattct ttaattttac ttaaatctaa ttcattgaac aatgaattta taagcaaatc
    27361 caattcttcc tcatcaagtg tagttggagt tccaccacca atatatagag tttcaacttc
    27421 tttcttagta tccttaataa ctttggcaaa ccccttaatt tcttcaatca atttataaac
    27481 atattctctt tttaaatgtc caaattgttt taatgaattt gaaggaaatg aacaatatac
    27541 acatctagtt ggacaaaatg gaatacttac ataaagagaa attttatttt tatctatagg
    27601 atacataaat aatcgctctc ttttagctat ttcaagagct aaatctattt tctcatctat
    27661 tataaaataa ttatctttta gaatggttct tatgctatta tcatctagct ttttatccat
    27721 taaattgtgg acaattttga ctggtctaat accagtcaaa attccccatg gtacataaga
    27781 attaaatact tgtttaagca ctacaaacat gctttttttg atattttctt tacacagctt
    27841 tttaaagttc ctcttacttt cactatctag gctattaaga aattcttcaa tcgttttgct
    27901 actatcaaat ccatctaaaa attcaagatt catattttct atattctgta ttgactcgta
    27961 ctttaagttt ccattttcat agtattcagt acttgagaat aatacaccat tctcataaat
    28021 caatctattt attaaatgct ttgactctat attattgtca gcattagagt ctttaaactt
    28081 aaattcactg gtaaataatt ttataagttc tgctacttca tacttataat catgtccttt
    28141 taaaaaaaca tacaacatca acttaactcc ttctatttaa cagtagaaga accccctcac
    28201 taatatagtt attaaatatt ttatactttt ttaaatacta atataaaatt acatgtaagg
    28261 atttgtcttc ttttcaaccc ctagagtact ggttggtcca tgtccaggat atactctaac
    28321 agcatcttca tatttgcata atttcttaag tgatttttcc atttggttaa agtctccact
    28381 atataaatca gttctaccaa tacttccagc aaacaaagta tctcctgtga acatttcatc
    28441 ttcaactctt atacacatac atccttgagt atgtcctgga gtatgcaaga aagtcatttt
    28501 taattcacca agttcaagct tgtctttatc atttacatag atatctgcat caaactcttg
    28561 tgctccacat ctcattgtat aacttagatt tttatttttg tcatttaata attctttttc
    28621 atcaacatgt gcaactactt tagcaccagt tttttcttta atatccttaa catatcctat
    28681 atggtctcca tgcccatgag taaggataat atattcaata tttaattcat tttcttttac
    28741 aaaacttaat gtctctacta aacttccacc tgggtctata actgcacatt ttttagtctt
    28801 ttcatcacct aatacataag tatttactcc aaaataacta tctacaaatt tttttataat
    28861 cattaaagtt ttccccctta aaaagattta cttgagtcta atagtattgt tactggacca
    28921 tcattagtta actctaccat catatgagct gcaaattgac ctgtaccaac tgtcacacct
    28981 ttatcttttg ctttttttac aaattcttca taaaggttat ttgcaagttc tggtctagct
    29041 gcattactaa atccaggtct tcttcctttt ctgcaatctc catataaagt aaattgagat
    29101 actactaaaa gctctccacc tatatccatt agagataaat tcatcttgtc attttcatct
    29161 tcaaaaattc tcagattcaa tattttatca atcatataat ctacatcact tgatttatca
    29221 tcatgagtca ctcctaacaa tactagtaac cccttattta tttgacctat agtgttttca
    29281 tctactgtaa ctttagatga agatactctt tgcactactg ctctcatagt ttcctcccta
    29341 ttattttaac tctaatttgt cattctataa atactttcta caccaggaat tgcttttaat
    29401 tttttcatta gaatttttaa ttcctctgtg tcattaacct ctacaagtaa gtttatactt
    29461 acaatactat ccttaccttt tcttgcattt attccgttta aactaagttt atccattgca
    29521 acaatatgag ttatttcatt aacaattcct cttctatcaa tagcttttat ttgaatttcc
    29581 gcttcaaact taccttttcc tgctgaactc catgaaacct ccaccaatct attttggaag
    29641 aaatcaccat tattgtttgc atttgggcaa tcagctctgt gtatggctac tcccctaccc
    29701 ttagtaatat atcctacaat ttcatctcct ggaagaggat tacaacactt agcaaatctt
    29761 actaagatat tgtcaagccc ttttactata attccttgtg atgcgttttt ctttctcttt
    29821 ttactgtatt ctgtttcact tatattgtgt ttatttaaat cttcttcttg tatctgttgt
    29881 tcctttttag cttttttaac ctcttttaaa tataggtctt ttaccttaga taccacttga
    29941 gatgacatta taccaccata acctacagtg gcaattaagt cctcaacact tggctgatta
    30001 aatttcttag caactaatgc catatatttt tcaacaagag ggtctttttg tggtatatca
    30061 tgcttcttaa attctctttc taatattgta tttccacggt caacattttc ttctcttctt
    30121 tccttcttga aaaattgtct aattctactt tttgcatttg gggtcttcac tatattaagc
    30181 caatccctac ttggtccatt agaattagat gatgtaagta cctcgacaat attaccattt
    30241 tgaagcttat aatcaatagg aactattctt ccatcaattt tagctcctac acatttatta
    30301 cctacatttg tatgaaccct ataggcaaaa tctataggtg ttgattctgc tggtaattca
    30361 attacgtctc cttttggcgt aaatacataa acttgactat taaatacatc ttctttaagt
    30421 gcatccataa actcttgtgg gtcttttaaa tctttttccc actccatcat ctgtctcaac
    30481 cattgaagtt tttcttcaac ctttgactct ttgctagaga taccttcttt atatttccaa
    30541 tgggctgcta taccattttc agctatatta tgcatctcat gagttcttat ttgtatctct
    30601 aaaggttctc catcaggacc tacaacagtg gtgtgtaatg attgatacat attgggtttt
    30661 ggcattgcta tataatcttt aaatcttcct ggaataggtc tccataatgt atgaactata
    30721 ccaagtactg catagcaatc ctttacatta tcaaccaata tccttactgc tgttaaatca
    30781 aaaatctctt caaaagtctt atgttttttt tgcatctttc tatatatact gtaaaaatgc
    30841 tttggtctac catatacatc acatggtata cttaaatctt taaacttatc tttaagaagt
    30901 tcaacaattc cttgaatata atcctctctt tgacttctct tcattgatac tctactaact
    30961 aaatcataat acccttctgg gtccataaat cttaatgctc tgtcttctag ttcccacttt
    31021 atcttggaaa ttcctaatct atgagctata ccaccataaa tttcaagtgt ctcttttgct
    31081 ttatactttg ctttttctgg aggcatgtat tttaatgttc tcatgttgtg caatctatca
    31141 gcaagtttta taagtataac ccttatatcc ttcgccattg ccaaaaacat ttttcttaaa
    31201 ttttcagatt gagtttcttc tttcgaacga tattttattt gaccaagttt agttactcca
    31261 tcaaccaaat ccgctacttc tttgccaaat tcttttttta tgtcttcata ggtatattct
    31321 gtatcttcta caacatcatg aagtaaacct gctgttatag tttcaatatc taattccatc
    31381 tctattaaaa tatttgcaac tgctaatgga tgaataaagt atggttcccc agattttcta
    31441 tattgtcctt catgcgcttt ttttgcaaga ttataggctt tttcaaccat ttcaaaattt
    31501 gcattaggtg cataaacttt tattttttca attatttctt gtaattcttt atcatgcata
    31561 taaccaccta ttttgtataa aattttaata tatatgaaaa tagttggtgt tataccaact
    31621 attataaaag tactagtatt ttataagaga attaacatca tagttagaca acttttctct
    31681 cccatttaag aattttagct caatcaaaaa ttgcatagaa actacttctc cacctaattt
    31741 ttctacaagc ttggcagcgg cttccatagt tccaccagta gccaataaat catctactat
    31801 tgctactttt tgaccctttt taattgcatc cttatgtatc tctaaagtat ctgtaccata
    31861 ctctaatcca tactcataac tctcaacttc acctggtaac tttccaggtt ttctaattgg
    31921 aacaaatcct actcctaaag catatgctac aggtgtaccc atcaaaaatc ctcttgcttc
    31981 tggtcctatt actaaatcta catctttatc tttcaattct tcaactatag aatccactgc
    32041 atatttaaat gcatctccat ctttaaatag agttgtcaca tctttaaaat ctatgcctgg
    32101 ctttgggaaa tcatcaatat tccttataaa gttttttaaa tccatgggaa acgcctccta
    32161 ataactgcta ttgtattgtt tttctaaatt ttttagatta ttgagtatta aactctcatt
    32221 taagtctaat tttttctgtg gttttggcaa tattcttatg agtacagaat ttttttcata
    32281 atttaaatta aagtcaagta aatttaattc tctaaataca tttaatatcg taaaaaactt
    32341 taatggaatt acattaaaag tttcccttat atttaccata tccaaatcaa tttctttttt
    32401 tatgagtgct tgtttataaa ttgttataaa ttcatctctt gatggaacta tattactaac
    32461 tacattcttt aaatataata ggtctgtttt attataatat tttataattt cactttcttc
    32521 tcttttattc tcatatatat acgaatattc gcctttattg tataaataat cataaagaat
    32581 aatattatta tatcttttta agtctatttt atcaatatta ggagaaaata taagctctaa
    32641 tttatcagta tttttgctat catcttcaat aatattgtaa tttatgttaa aatccaaatc
    32701 tataagtgat acatctgaca ttgctctata aaatccattt atagaattag atattattag
    32761 tgtatctttt tcaaaataat caaatatatt tatatctgta tttccatcaa ataattcaaa
    32821 atcagacaca gatatattat acaggctttg agtatctttt ggtattattt ttgacattaa
    32881 tttcaatgaa agtttgtcat tacttgcact tttaggtcga gccaatcgta tatctttaag
    32941 taaaaattgt actttcctat ttcccatata gttattttca tctaattgga atagtacatc
    33001 taccttgtct cctactttat acattgattt taaatgactc atattaaatc ctatacattc
    33061 atagcttttc tctttttcta tgtttaattt cagatgttgt tgattcttac ctataacttt
    33121 caaatctttt aaaatataat ttctaactat aaatctagga ttaggattat ttaatccaaa
    33181 gggttctaac ttatgtaatt cttctacaag atttaaattt attacatttt cttgtaattc
    33241 aaactcaaca tttacattct ctatcatatc atcttcagtt aaattataat ctgcaaattt
    33301 atttatttca tttgctaaaa tttctacatt gtctgaatcc aaggataacc ctgctgcttg
    33361 ttcatgacca ccaaacttag tcatcaagtc tttgcacttt atgagagctt caaatatatt
    33421 aaatcctttt attgacctcg ctgaaccagt agcctcccca ttttctatac ctagaagaat
    33481 tgttggtttg tagtattttt cagttaactt tgatgctaca attcctatta ttccatgttg
    33541 ccaaccctct ttagctaaaa ccaacacctt gtcatcattg tatctgctat tagactttag
    33601 catttcttca gcttcatgat acatcttagc ttctatcatc tgtctttcat tatttttttc
    33661 ttccaatata ctagctattt ctactgcctc ttcttgtgat tgagtagtaa atagctctac
    33721 tcctaagtaa gaatatccca atcgacctga agcatttatc ctaggaccta ttgcaaaacc
    33781 tatatgagaa gaacctatct tatcactttc tacaccacaa acttttataa gctcccttaa
    33841 tccaatattt ttgccttctt tcattgattt taaaccattt tttacaatta ttctattttc
    33901 atctataagt ggaacaatat cacaaatagt tgctagtgtt actatttcca aataattata
    33961 catactagtt ttaaattctt cttttggagt caaggcttga atcattttaa atgctacacc
    34021 acatccacat agtgaatcaa atggataatt acaatcttct tgttttggat ttattactgc
    34081 aaaggctgat ggaatttcac tttgacattc atgatggtct gtaattataa catctatgcc
    34141 caaatcattc gctgtattga cctcagacac tgatgtaatt ccacagtcaa cacttataat
    34201 caagtcacat cccctagagc ttataagctt aatagcatct tcatttatac catacccttc
    34261 ttctaatcta ttaggaatat agtaatcaac attgtaacct atactcttaa aatataagca
    34321 caagatagat gtagatgata caccatcaac atcataatct ccgtaaatcc aaattttttc
    34381 gttcttctca actgctaact ttattctatc aacagctttt tgcatatctt tcattaaaaa
    34441 agggtctctt aaataatcta aagatggatt cataaatatt tctgaatctt tttcagtaca
    34501 tatccctcta ttttttaaaa tttggcagat ttccggggaa atattaagtt ttttgctaaa
    34561 ttcactttcc tctatcttac ctttatactt caatatccat tttttcaaat ttaattcccc
    34621 ctaatctttt ttgtattttg acctaatact tcttataact aagcaaaggc ctattataaa
    34681 ggatataaag aaacccgcta ttgcagtaaa ttttatccat atattatttt ctatatttgg
    34741 agatgcaatt ataagagaag aacctactat aatagatgcc aacactaaac tcaaagatat
    34801 ttgagatgtt agctctatta tacaattttc taacctcgtc attttaacat cttcaatttg
    34861 catttttata ttatttcttt ctatattttt taaaattgct tttaattgct ttggaatagt
    34921 ttttatgtcc agtaatattt cttctacatt ttgtcttgaa cttaaaacaa catttttagg
    34981 gttaaattta ctcttataat gatgtttcat aaactctttt cccatagaac caaaagaaaa
    35041 atctgtgttt aaagttctac ttgttccttc taatgttata actgtctttg caagagttac
    35101 aaattgtgca ggcatgacta ttttatactg tctaaaaaac ctaaatagtt catttaatat
    35161 atctgttaca tttatttttt ctatagaaat atcatagtaa taatgtatta gataaagtaa
    35221 atcctgtcta agtcccttaa tatcagcctc tccatttaat gcatccattt ctatcaatag
    35281 atatattatc ttgtcaacat tcttttctac acctgctaat gcaatttcat ttaattggtt
    35341 taaagtttta ttatcaataa ttccaatcat tccaaaatct atatatgcta tcttattttt
    35401 agcaactacg aatatattac ctggatgtgg gtctgcatga aaaaatccat gagataatac
    35461 ctgtgtaaaa aatgacctaa ctcctatttc aacaatagtt tttgtgttat aacctagtct
    35521 ccttattttt tctacatcac ttaactttgt accattaact ttctccatta ctaaaatttt
    35581 cttagtatta tattctgagt atactttagg tatatatact tcatcactat ttttaaatat
    35641 cctagagaat ttagttgcat ttatagcttc aaatgtataa tcaagttccc tcattaattg
    35701 agtttgaaat tcttcaatca tctgtactaa atctaaatta aaatcctttt ttaaatcttt
    35761 taaagtattt gcaatagttc taagaatctc taaatcagat tttattattt tctctatatt
    35821 tggtctttga atttttacga ttacttcttc tcccgtttta agtacacctt cataaacttg
    35881 accaattgaa gctgctgcta ttggttcttc tttaaattct aagaatattt cttctatact
    35941 taaacccact tcttctttaa atatatcaat agctatattt gaatcaaatt tctctacatc
    36001 atctctgagt tttgatattt catcaattat atcctggtct aacaagtctt ttcttgtact
    36061 caatatctgt cctattttta tatatgtagg tcctagttct tctaaaactc ttttcattct
    36121 ctcaccagtt gtcatatttt ttatttcttc tggtgggtca aatagtggta ttttataggc
    36181 aattccttct atatttagtc tttctacaat aaaactaaaa ccatacttta ttaaaacata
    36241 tccaatttct ctatatcgct ttaaatttct ataacttatt ctcaaatctt ttcactccta
    36301 agataggtat acccaaaaac ttacacctta atttatcgta tatgacatta tttcaccaat
    36361 tgatattcta atatcctata tcctctttaa tatttaattt tatcacatat actaccaatt
    36421 ttattaaaat tatttaactc agttaatttt tatttttgac attttatatc tggtttaatc
    36481 aaatactttt tgaaaactaa aatatcaaca aaatctaata aaataaatta gtggttgcct
    36541 caaaacagat ttaaatatgt tttgaaacaa ccactcttta aactaatatt tttgattttg
    36601 tgctgcctct aaataccatt cataagattc atcaatatat tttttatctt cttctgtaag
    36661 ctctctaaca accttaccag gagaacccat tatcaaaaca cctggtggaa acttcttatt
    36721 agatgtaatt agtgtacctg ctcctatcag agtatattct cctatttcag cattatccaa
    36781 tattattgaa cccataccaa ttaacacatt atcactaatt ttacaaccat gaactataga
    36841 cctatgccca actgttacat tgttaccaat tatagtttct gtatctccat gcactataga
    36901 acaatcttgt atattagtgt tttctccaat agttattggt ccttcatcac ccctaactac
    36961 tgcattgtac catatacttg aatctttgcc tattttaaca tttccaatta catctgctga
    37021 ttttgccaca aatacacttt cgtcaattaa aggtttatct tctaaataat ctctaatcat
    37081 atataaacaa ctcctttaaa atataaattt agttggttgc tccttctaac attaacttag
    37141 cttgtatcat tatagagcac tctgtacgtt ttctttgcat ttcacatcct aattcatatg
    37201 gttttgatat gtcattatta aagtttatcg catttgcatg acatccacct gaacagtaaa
    37261 acttattcca acattgttta cactcttctt tagtatatac atgagcttct ctaaacatat
    37321 tttttaaatt ttctggaagt actatttctt catcaaatat atttgccatt ttaaattctt
    37381 catttccaac aaattgatga catggatata tatctccatt tggagttaca gaaagatact
    37441 catttccagc tccacatcca gttattctct ttattacaca tggaccttga tttaggtcta
    37501 tcataaaatg gaaaaattta aatccatctc cttgtaattg tctatctgca tactctacag
    37561 caaatttttc gtactcttca aatatcttag gtaaatcttc ttctctaagt gcatatggat
    37621 tactctcatc tccaacaact ggctctacag aggttaattt aaatcctaaa tctgcaaaat
    37681 gcataacatc ttttgaaaaa tctaaattat ctcttgtaaa agtacctctt atataataat
    37741 acttatcttt tgctcttttt tccacaagtt tcttaaatcg tggtaatgta atatcataac
    37801 ttcctttatc atttaaagtt ggtctcatat tatcattaac ttcttttctt ccatctaaac
    37861 ttaaaactac attatgcata ttttcattta tataatctat aatctcatca tttagcagta
    37921 caccatttgt agttattgta aatcttatat ttttattata atctttttct acacttcttc
    37981 catagtcaac cagttgtttt acaacctcaa agttcatcaa aggctctcca ccaaagaaat
    38041 ctatctctag gttctttcta cttcctgaat tagcaatcaa atagtcaatt gctgccttac
    38101 caacttcaaa actcataagt tctttttctc ctccaaaatc accttgagct gcaaaacagt
    38161 atttacattt taagttacaa tcatgagcta catttaaaca taaagctttt actacaggct
    38221 ctctatgtac aaagcttgga tgatattgat atgtatcttc tgtatataaa agaccctctt
    38281 tttccaaatt taatatttct tcatatgctt catttatttt ttcttcttga tattttgatt
    38341 ttaatatctc taatatttct tctttacttt tttctttata aaaatctaac aaatcgtatg
    38401 caacatcatc taacacatga acagctccac cattcacatc taaaacgata ttatatccat
    38461 tcatagaaaa tttatgtatc atactcatac cctacctcct aaattactat ctatactaaa
    38521 gttttttatt attttaatta aactttaccc ttcattatat cataagttta cataaaatac
    38581 atacaataca aaaatgactt actctccgta agtcatttca ttaaatacac tatatccccc
    38641 taaattggcg cactaatata ttaccaaata ggtattaggc tcctataaaa taaataaaat
    38701 aaattttgta tctgatttta tattgtttta atcttattaa aatataataa tttctttttt
    38761 cctgataatt ttgtataaat aagtgcttgt atttaatttg tcttctttag attgctgatt
    38821 tctttgggta ctttaggctg atgaataatc caaggacagg tactattagc tgacaaaata
    38881 gcagtgctaa gtgccaatga gctagcaaac ttcataaatc ttacaataaa ctttttcata
    38941 acttaactct ccctcataca tattttactt atactttagc ttttaactta cctaatacta
    39001 acatcacaaa aatccaaaac atggcaaatg cgctatatgt gaaataatct acaaatatac
    39061 tcaaagaaag acttaaaatt gttatcaata acactactgt agatataaat atagcagttt
    39121 tcttataaac caatttttcc ctatcactta tagggttact cctatgttct attgggcaca
    39181 gaacacaaat tccaacccaa ctaacacttg caataatcat aataatattt ttaaataagt
    39241 ctatatttat attttctata attaagattg tagataaaat tataaaaata aaggttaata
    39301 agcatctaaa ataattgtct gcatgatacc ctcctgaaaa ttgtcttatt ggacaataac
    39361 acattaaaaa aaataataca tatgtaaatt taccaaataa aaaacctata aacagcatgg
    39421 tggttatatt aactatgaaa gctattaata tttcaaatcc ataagaatag actttagatt
    39481 cattattatc tatcatatta ttacaaatta aaacagatgt cattttttca gcatatcttt
    39541 taaacatttt tacctccaaa aaaattttac atatatagag tacattcttt tttgagaaaa
    39601 ttcaatatac tttacaaaac tagttgttaa aaatgtaaaa ctggtcaaaa aaagacctat
    39661 ataattttct tcttattatt tatataacaa aacaattata ataaaacaat tttatcaagc
    39721 tttatatgca taaaaagcct atgtcaaaat agaaataaac cttttcccca ttgttaaaag
    39781 gctaaaaata tatttcattt catataaaaa gagtacctca caaactaaaa agttcctttt
    39841 gagataccca ttttatttat tacaaaatat caaattttat ttatttgcat atgttttcta
    39901 tatattttag ccttttaact ttgtttttgt tttacatact gtagtgcttt tctattctgt
    39961 tttactgctt caagacaaac tttttctgtt tgattatcaa caaattctaa agctctataa
    40021 ttttgcttta ctgcttctaa acatattttt tctgtttgat tatttacata tttcaacatt
    40081 ctataatctt gttttactgc ttttagacaa acttcttctg tttgttcttt cacatattta
    40141 agcgcttcat aactttgatt aactgcttct aaacaaatct tttctgtttg ttcctttaca
    40201 taagctaaag cattatagtt ttctcttact gcctctaaac atattaattc tgtctgattt
    40261 tctacatatt taagaatttt tccattttgc tttactgctt ctacaaatat tctttctgtt
    40321 ggtatcttta cataacttaa tatttctttt atttcaagtt cttcaaatga acctcttact
    40381 gcttctatac atatattttc agtctgtttt tttacatatt gcagtacttt tccattttgt
    40441 ctaactgact ccaagcaaat ttcttctgtt tgctctttta cgtactgtaa tgctcttcca
    40501 tcaattctta ctgcttccaa acaaatctct tctgtttgct tatttacata ctgtagagcc
    40561 atataacttc tttttactgc ttccatacat attttttctg tctgttcatt tacataatac
    40621 aatgcaaagt cattctgttt tactgcttct atacatattt cttcagtttg ctcttttaca
    40681 caagatagtg cactgtagtt ttcttttaca gcttctaaac atatactatt actttgttcc
    40741 tttacataag ctaaagattt tccatctttt tttacagctt ctaaacatat ggctggagtt
    40801 tgctctttta ttccttttaa tatctctgca acatcatttt tagatgccct ttctataaat
    40861 gctagacata catcttctgt ttgctcttcc acaaatttaa atacttccat gacatcataa
    40921 gttgatgcat tttttatagc ctcaattagt acattttctg tcttattatt tatgtagtac
    40981 aaagctctgt agttctgttt tactgcttct atacaaatat cctcattttg atttgttata
    41041 tacttaagag atttatatgt ctgttttact gcttccatac atactttata agtcttgtcc
    41101 tttacaaact caattatagt accatcctgc tttactgcta gcagacacat ctcttctgtt
    41161 tggttttcta tgtcttttaa ctctctgtaa tcatatttta ctctgcttaa atcatttaaa
    41221 tgtactttgt tatcttcctt taaatcttct tcattatttt ctatatcata ctcaaattct
    41281 tcatcatcta aatagtcatt tttttctggt aaaaatatag atttaatttt attctttata
    41341 tccataaaat tatcctcctt taatatgatt ctatcattaa agtaaatcgt ttttaagcac
    41401 tt
//
LOCUS       DAFAZV010000038        41205 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFAZV010000038 DAFAZV010000000
VERSION     DAFAZV010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 41205)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41205)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41205
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.038"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..1055
                     /locus_tag="KOU88_002694"
     CDS             <1..1055
                     /locus_tag="KOU88_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3212563.1"
                     /translation="SADNFIIIMKYIEEEDITKRLKTIFEELDLFNNNQEEKYKLVLS
                     CGIYFILPEDRDINSIIDRANIPHKMAKGGHKSSYAFYDNKIHDQEIKEKEMENTMFS
                     SLENKEFIIYLQPKIELNTGEIQGSEALVRWKRPDKGLIPPNEFIPFFERNGFVINLD
                     LYVLEEVCIYLRKWIDAGINPVTVSVNVSRIHLYCNNFIETYKNIIDKYNIPAKYIEL
                     ELTESIIFDNFDILIDIMNNLKKIGFLISMDDFGSGYSSLNMLKEIPMDILKLDQKFI
                     METYNSKRSKIIVTKVIEMAKELGMKVISEGVETEEQFKLLKEVKCDMAQGYLFGKPM
                     PIEEFEHLIVSNLVRG"
     gene            1231..1599
                     /locus_tag="KOU88_002695"
     CDS             1231..1599
                     /locus_tag="KOU88_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3212564.1"
                     /translation="MEWELDNNKPIYIQLVEHLKLKIISGEIKIGSKLETVRALAEDA
                     EVNPNTMQKALTELERQGLVYSQRTKGRFVTDDKEKIKAMKEEIANVEINTLKVTLEK
                     LGYDRDEMLKLITENLKGEL"
     gene            1601..2326
                     /locus_tag="KOU88_002696"
     CDS             1601..2326
                     /locus_tag="KOU88_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212565.1"
                     /translation="MDKNISNVSQDGIVEFKGVNKSYGTKNVLKNIDLNIPKGKIVGL
                     LGPNGSGKSTMIKLMNGLLQPDNGEIMINGMKPSIDTKKIVSYLPERTYLNDWMKVSD
                     LLKFFYDFYSDFDVRRANEMIKSLDIDVNEKLKTMSKGTKEKVQLILVMSRNASIYIL
                     DEPIGGVDPAARSYILKTILKNYSEDSTLLIATHLISEIENICDEIIFISKGEIVLQG
                     DVEAIREEKGKSIDALFREEFKC"
     gene            2320..3084
                     /locus_tag="KOU88_002697"
     CDS             2320..3084
                     /locus_tag="KOU88_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212566.1"
                     /translation="MLGKLLKYELKASGRIFIPLYIAILIVAVFNGIFMNTNILQVQG
                     IGILVLTSLFMALGVLTIVVTIQRFRKNLLGDEGYLMFTLPVSTSSLILSKCITALIY
                     AVLSFIVAVFTFGVLMLFGTSGILLPEILDLFNTSFKWISENFLDILLLVVVMFISYS
                     SFILLLYTSISMGQLPKFNKHRNIVAFASFIAINIVISIVGDAVGSILPNEDTNMVYH
                     LYQSPSFMLAILGSLVVAIALFFATKFILDKKLNLE"
     gene            3306..4556
                     /locus_tag="KOU88_002698"
     CDS             3306..4556
                     /locus_tag="KOU88_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3212567.1"
                     /translation="MKSYTKAKWSVWGIITFSFVLVLFLRMSTAVVSDNLANELGFNS
                     IQISNIASFCLYAYAFMQIPAGILIDKYGARKISSLGIIMASLGSILFGLIQSIELAY
                     ISRVIVGAGTSVILLCILKIQGRWFNKSEFASATAKFSFVGNLGGVLATFPLVFLSEL
                     VGWRNSFLLIGIIGVVIGCFMYIIVRDTPKEYGFNVDTEPYEKSEKVNIVDGIKSVIK
                     NKSTWYNSMIMFSFVGLTSAFISLWGVRYIMDVYGVSKSFSAFIVSFFTYGFIFGSII
                     MDFVFAKIRSSKFNIIKFGAMIDLFIWIVIVVVYQVKPPIIVLPISFFIMGCIVMSHL
                     QVFNDAKYKNKEIYSGLATSVINTFEFIGSGIINLIIAISLQVNSYNIVDGYKKGFVV
                     FIVLSIITIVSSHIGVKNDDFKAI"
     gene            4747..5631
                     /locus_tag="KOU88_002699"
     CDS             4747..5631
                     /locus_tag="KOU88_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBK3212568.1"
                     /translation="MDTTKIDDISKLDLNNLDINKMDMGGIMESLLEWATTSGVKLII
                     GILILSIGFKIIKKFVNHVMLLLSKRDIDLTLRKFLKSLLLSVLKVAVIIIVLEYWGM
                     SLSSFAAVIASAGVAIGLALQGSLSNFAGGFIILLIRPFKVGDYVEAAGHGGTVEQIG
                     LFYTQLVTPDNKQILIPNGSVSNDSLINYSAKNTRRVDLTFSVGYEDDILHVRRVLKD
                     IVNNHKLIINEPEPFIGVVEHGDNAIKFATRVWCKTEDYWTIYLDLLEEVKVRFDEEG
                     ITIPYPKMDLTVKELNKI"
     gene            5993..6610
                     /locus_tag="KOU88_002700"
     CDS             5993..6610
                     /locus_tag="KOU88_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBK3212569.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            6718..9249
                     /locus_tag="KOU88_002701"
     CDS             6718..9249
                     /locus_tag="KOU88_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK3212570.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            9683..10384
                     /locus_tag="KOU88_002702"
     CDS             9683..10384
                     /locus_tag="KOU88_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBK3212571.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            10434..11516
                     /locus_tag="KOU88_002703"
     CDS             10434..11516
                     /locus_tag="KOU88_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3212572.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            11777..12877
                     /gene="vanG"
                     /locus_tag="KOU88_002704"
     CDS             11777..12877
                     /gene="vanG"
                     /locus_tag="KOU88_002704"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBK3212573.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            12874..13680
                     /locus_tag="KOU88_002705"
     CDS             12874..13680
                     /locus_tag="KOU88_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBK3212574.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            13698..15836
                     /gene="vanT"
                     /locus_tag="KOU88_002706"
     CDS             13698..15836
                     /gene="vanT"
                     /locus_tag="KOU88_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBK3212575.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            16150..16770
                     /locus_tag="KOU88_002707"
     CDS             16150..16770
                     /locus_tag="KOU88_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBK3212576.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(16936..17472)
                     /locus_tag="KOU88_002708"
     CDS             complement(16936..17472)
                     /locus_tag="KOU88_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBK3212577.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(17585..18259)
                     /locus_tag="KOU88_002709"
     CDS             complement(17585..18259)
                     /locus_tag="KOU88_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBK3212578.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            18462..20336
                     /gene="asnB"
                     /locus_tag="KOU88_002710"
     CDS             18462..20336
                     /gene="asnB"
                     /locus_tag="KOU88_002710"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBK3212579.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSASFSVKGYSELEVAKKTADKLGIENIQINITQDEYIKSLPNVIY
                     SLDDPIADPSEVGLYFLIKEAGKHVKVALSGEGADELFGGYNIYKEYSTMKSVVNSPT
                     YIKSILGRVSELMPNIKGRNYLYRATTPLEKRYIGNAKVFENSEVKRFFFKYKEKNIY
                     EYLLSNLYRDAQKNNYDYISKMQHIDVNTWLQGDILQKISKLSTAEQVELRVPFLYKD
                     VFDVAKNLRMEQKINKNNTKVLLREAFREIVPEHVVQRKKLGFPTPIRVWLKDSLGDI
                     VKETIYNSNVDEFIDKKYAIKLLDTHLKGHRDNSRKIWTIFTFCLWHQLFIEHKNVEY
                     "
     gene            complement(20428..21864)
                     /locus_tag="KOU88_002711"
     CDS             complement(20428..21864)
                     /locus_tag="KOU88_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBK3212580.1"
                     /translation="MICTIKPLKISIKKSTEPLIEFISDTTYKNKSSSYIKEVYFTRY
                     IGVDDSIDKYIEKIKNIDTYFFNNPTIPYIRLNNLKINFDKEQTDKMLKIFNIYDSSK
                     FNSWDLYNIDFPCKIENDTLNWTKKIAFKNTLDLFSTSMPNCTSSIIKNFAVKLLCWI
                     DYFLPKLFYNKVKTTISPKIVYFGNIKRQELFFLYFLSQLGCDILYINPNKDILDLYP
                     ECSKFSTLFELSRKTPNILEIPFERHITNINYSENTNKTSPTTNKPNSKNTLNNTNLT
                     SKKIVQDEEVELSYEDLAKLSASVVMIVVCNNENKPFKSGSGVVINNEGYILTNLHVV
                     NDGYSFLVRFENDDKVYTSYQIIKYHSDYDLAVIKVNRKCKPIPVKVSKKPVRGQKIV
                     AIGSPLGLFNTVSDGIISAFRDFETVQMIQFTAPISSGSSGGALLDMFGNLLGLISAG
                     YDDGQNLNLAVESSLVKIFANNFIEIVN"
     gene            22193..22771
                     /locus_tag="KOU88_002712"
     CDS             22193..22771
                     /locus_tag="KOU88_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBK3212581.1"
                     /translation="MGITLSKGQKVDLTKGNPGLKNILVGLGWDTNKYDGGFDFDLDT
                     AAFLTGASGSVTNDGDFVFYNNLKHTSGAVEHLGDNRTGEGDGDDEQIVVDLSKIPGE
                     ISKISFTVTIHDATERRQNFGQVSNSYIRIVDKDTNEELIKYELGEDFSIETAIVVAE
                     IYKHNGEWKFNALGSGFEGGLAALCGNFGINL"
     gene            22810..23388
                     /locus_tag="KOU88_002713"
     CDS             22810..23388
                     /locus_tag="KOU88_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_126936537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBK3212582.1"
                     /translation="MAIVLKKGQKIDLTKGNPGLKNIKLGLGWDTNSFDSGYDYDLDV
                     SVFMVGESQRVEKDEDFIFYNNLKHPSGAVEHLGDNRTGEGDGDDEEILVNLETMPKH
                     IQKIAVTVTIYEAAERRQNFGQVSNSYIRVLNSENDEEILRYDLGEEFSIETAITVCE
                     IYKYNGEWKFSAVGAGFEGGLEALCRNYGLNV"
     gene            23474..24103
                     /locus_tag="KOU88_002714"
     CDS             23474..24103
                     /locus_tag="KOU88_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerD family protein"
                     /protein_id="HBK3212583.1"
                     /translation="MSINLSKGDKIDLKKSNPGLSNILVGLGWDPVQQSGGGFFKSLF
                     GGGQADIDCDASVFMLNQEGKLSGIKDLIYFGNLKSACKSVLHTGDNLTGEGTGDDEQ
                     ILVNLDKVPSNIHKLLFVVNIYNCVDRKQHFGMIENAYIRVEDQGNKKEIAKYNLSDN
                     YSEKTTLIVGAIYRKDGSWQFKAIGEGTKDAGLKEVMQNLDRIECAYGI"
     gene            24093..26852
                     /locus_tag="KOU88_002715"
     CDS             24093..26852
                     /locus_tag="KOU88_002715"
                     /EC_number="7.2.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium-translocating P-type ATPase, PMCA-type"
                     /protein_id="HBK3212584.1"
                     /translation="MEFNNDIKYYNVDKEEVTKDLSVNPEKGLSESEVKTRREKYGLN
                     EFTPKEEGSFWDDLKESLSEPMIVILIIAAVVSAVIGETHDAIGIVGAIAIGIAIGMI
                     TEGRSKKAAEALSKLTENIEVKVLRDGEVHQISKSELVPGDIVYIETGDMVPADGRLI
                     ESINLKIREDMLTGESDDVSKKCDVVVSMEEIESKGAVVVQEPIPAKQINMVFGGTLV
                     AYGRGALVVTSIGDNSEMGKIAQNLSETDEQTPLQIKLGNLGGLIAKVSSAVAGLLFI
                     FMVFQMISKNVLNVDMSGILPFLESIDPVKTAFTVCVALIVAAVPEGLPTMINMTLAI
                     TMQKMAKINALVTKKEACETIGSVSVICSDKTGTLTENRMTVEVAYVDGRYIESSEEE
                     INSYFEENCMINSTADVEHNDGDIKYLGSATECALLLYYKNVDYRQVRKNSNIVAQNP
                     FTSDSKRMTSVIGQDNHHVLLSKGAPEVLLELCSHIQRGKDIVPLTENIKHEILEEIK
                     KLQIKSMRTLGFAYKEISQAEEEAAVTAESDAMNVSAMENNLVFSGFVGIRDPLRKDV
                     IESVNTANKAGVSVKMLTGDNINTARAIGEELGLLKNNMRVVEASYIDTLDDEELKQE
                     IQSISIVARSKPDSKMRIVSALQKSGDVVAVTGDGINDAPALSKADVGIAMGISGTEV
                     SKNAADIILTDDSFSTIVKGIKWGRGIYDNFQRFVQFQLTVNVIAFLVAIISQVMGQE
                     MPFTTIQLLWVNIIMDGPPALALGLEPVRDHVLNRKPVDRKANIISKSMVYTIVLNAF
                     YITAILMLQSTFNFLGVDEAHKGTVMFALFAFSALFNAFNCREFNADSIFPNFTHNKL
                     ALQIIVLTGIAQVIFTQLFQDFFNSVAMDFMTWVKVLCVAASVIVVNEVVKCIIRLVK
                     PKKTA"
     gene            26939..28501
                     /locus_tag="KOU88_002716"
     CDS             26939..28501
                     /locus_tag="KOU88_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceG family protein"
                     /protein_id="HBK3212585.1"
                     /translation="MGDSKVFEKIFSSQSDRGNYTPSKGYLSYFISYIGLEDEVLYNL
                     EIFKTKQNIDSKKDIALFTDVIANPSDFDIINYFKSGLQKYRTSMEDVDINILGFEEI
                     DYKIKQAMDRVLKEEEKEFTNDRVKQNFIVKIMAWIKIYIGALDINKNEAPKVIFYGD
                     IKKHEVYLLLILYLAGFDVLYLNPNSKSNIDILKSERYNIEFEEANIIEEKISFEERV
                     ILGEKIDKSSVKKAFTVGAEASKRISEELLNDAGFIKPWQLQDRKIKNLLLSSTVDEI
                     SIYWNQPLKLRPGFKFNDAIVEAPNFLSKINGIYNDKNEYIKFLDLLRDSESSTFIEF
                     NGDVDRFSKAFTREAFSLSFLLDSKGAIDKNSVLNNKDYSISTLALNQQIMILEKVEE
                     LLEGSMFLNGLSGEDKIKGLFTVLHMDKKFVHMMNNFDYSLINPKLIIYMYKSIVFDK
                     EIVFLMLLLSKIGFDIIILCPGGENNIENVINNQLIDVHRLDKMVYDLKLNSLENDIP
                     LLKKIFGKRRRF"
     gene            28502..29638
                     /locus_tag="KOU88_002717"
     CDS             28502..29638
                     /locus_tag="KOU88_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBK3212586.1"
                     /translation="MGININSFSKDKNSVEVTENLPTAVQEENFDIMEYTNNKKNELR
                     KSKEVEALTSLIEVENPDTILQFGRKASEGVARVSDSLLNTIKLNRNEENSKMLVHLT
                     KIMDKFDLDDFQETKEPNFVQKLFKKANNAIEMMFQKYETLGGEVEKIQIELEQYERD
                     IALSNKQIGAMLNENFEFYNELQKYIVAGEMAIEEMDNEILPFFKQKSETSGDQMDVV
                     NYQELLKVYDMLNQRVYDLRIAENIAIQTIPMLRGMQHNNYGLIRKINSAFVVTLPVF
                     KQCLSQAILLKKQELQAKSLKALDDKTNELLLRNAQNVSTQSAQIARMAGTSSVQIET
                     LEKMYNTIKSGIDETMRIEENNRALIKDNTKRLEELNTTIIYNK"
     gene            29702..30778
                     /locus_tag="KOU88_002718"
     CDS             29702..30778
                     /locus_tag="KOU88_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HpcH/HpaI aldolase/citrate lyase family protein"
                     /protein_id="HBK3212587.1"
                     /translation="MKYFDYICKDDLEKIFLKEPEDFSAKTEKDVLKYALGAFLYVPA
                     TQYNMIYKSIIGDVKGVRPLAICLEDAVGVNGELEAIENLRLILKNISNESITNKDGI
                     PLIFVRIKDVEQLLRIKEIIIKNRHSITGILIPKANSELIENCIEALDSMNLQDMYVI
                     PIIETKEFIYNEKKELSFTNLYNAILRHKSRILSIRVGITDILGMYGIRRDKNFSIYN
                     NLICSSFILDIITYLQRPELDIPISGGVSEFFDMTNKDIRNKYIEEILLDKYHGLIGK
                     TVIHPMQIQIVQALSTVSYEDFTDALDILDSTDSKYGVSKGVLGERMNETNPHFLWAK
                     KTLILSKIYGVLNKGVDYEELLKF"
     gene            30756..31994
                     /locus_tag="KOU88_002719"
     CDS             30756..31994
                     /locus_tag="KOU88_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyltransferase family protein"
                     /protein_id="HBK3212588.1"
                     /translation="MKNCLNFNCEIDIIDNPLNLELNDFLDVGIRNNSKRRFLFISKK
                     LGKHLACKPSEMDNLGKLMATIYNEKNKEESNGTVIAFAETGTAVGHSFFDYLCGDYE
                     FIHTTREQFDELENLEFLEEHSHATDQNLYFGMLNNFKFGDEIILVDDEITTANTCMN
                     IIRKIQSIYPKKKYTICSILNWVSDENLSKVTRLERELDCKIDFVYLFKGNFKFYIDE
                     DIISNYNDNYSITKLETISSDKVNLVVNHIYVDLEDYIGNKKYVKYTGRFGINRREQF
                     RLKEIVKRESKKITMASKESLKNEKEKILFLGTEEFMYIPMLFAKEKENQYDIYYHST
                     TRSPIINIDKNNYPIKSKFMLKSFYNIDIQNYIYNIDKHNFSKCYLFVELNKSENSYL
                     EFIDIIKKTSIKELTIVCCS"
     gene            32048..33136
                     /locus_tag="KOU88_002720"
     CDS             32048..33136
                     /locus_tag="KOU88_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease StiP family protein"
                     /protein_id="HBK3212589.1"
                     /translation="MRDFSTYSKDDVIFLLKDISNLIEEEGNKERELKIQNGRHYSEM
                     IPIEYEVSEDYLNLYHEKLRENKDKLAFSIGVMCEKIIKKNGNDVVLVSLARAGTPIG
                     ILAKRYIRSKYNVSLPHYTISIIRDKGIDMNAIEYIVKNHPSSKIQFLDGWTGKGTIS
                     KELEKACDELNVKFKKYFDSTLAVLADPAGYSGLYGIREDFLIPSACLNSTVSGLVSR
                     TVLREDLISKNDFHGAKFYRHLKDKDESMNYIETIEECFKNQFKNISDEVENWESDII
                     TRDGYFDVLNIKEKYNITDINFIKPGVGETTRVLLRRVPYKILVKDLNDKSLDHIFIL
                     AKEKNVEVEQMDLKAYKCCGIIKNMKDI"
     gene            33164..33955
                     /locus_tag="KOU88_002721"
     CDS             33164..33955
                     /locus_tag="KOU88_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD hydrolase family protein"
                     /protein_id="HBK3212590.1"
                     /translation="MIVFSDLDRSIIYSNKFLNADSKYANIEIYREKEISYISLDTIN
                     LIKQIQYYGMFIPTTTRTVEQFKRIEFNKYGIYFPWSITSNGGVILKDNEILKSWSEK
                     IDKLKSDYEPIESMIHKFKDYLNVDGITNFKVAEDTFFYIVVDLSRFNLDSIKEYTNI
                     LESKNWKFYVSGRKIYFIPKEISKENAIKYLTKELGIEYFYAVGDSIMDYGMLNISNK
                     SYVLKHGDINKNEIENSFISSSFNGMSGTEEILSNILDENCLLNI"
     gene            complement(34070..34624)
                     /locus_tag="KOU88_002722"
     CDS             complement(34070..34624)
                     /locus_tag="KOU88_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBK3212591.1"
                     /translation="MNIDVGSKIRSLRKSKNISISTLAKNSDLSTGLISQIERNMVVP
                     SIVAMWKISKALDINIGYFFEEIGREDSDIVVKKNNRKKIVTNDSTKFYELLVPNLSG
                     KKIEFILVTLDGHTHKNSEFVTHEGEECGYIIKGKMKITLGNKEYLLEEGDSFYFNST
                     IPHVYENYDDEVCISVWAMTPPSF"
     gene            34820..36022
                     /locus_tag="KOU88_002723"
     CDS             34820..36022
                     /locus_tag="KOU88_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 domain-containing protein"
                     /protein_id="HBK3212592.1"
                     /translation="MKSFVSPDNIWVLWAVVTGWAAFSIYLEQKYNWASKVSGAIIAL
                     VGAMLLSNLNIIPVESVVYDQVWGYVVPLAIALLLYQCNIKKIWKESGRLLIIFLVGS
                     VGTVLGAMIGFLALKNVVPDLNIVAAMMTGSYIGGNVNFAAMSGAFDAPGELVSATVV
                     ADNLLMALYFFVLIAIPSIGFFRKHFKHPHVDEMESIGITEGETVAANYWGRKEISLK
                     DIAIAIGSAFIIVAVSVELSTWFKAIIPLSNPFLAMLNTLFGNQYLIITTLTMLFATF
                     MPNFFGDIKGAQELGTFLIYIFFVVVGVPASITLIIQKSPLLLLYCGIMVLINMLVTF
                     IVAKIFKFSLEEAILASNANIGGPTTAAAMAISKGWSKLVGPILIVGTFGYIVGNYFG
                     LLVGNILI"
     gene            36079..37059
                     /locus_tag="KOU88_002724"
     CDS             36079..37059
                     /locus_tag="KOU88_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBK3212593.1"
                     /translation="MIFDGHSDTWADVTIRRLNGEKDVFRRIHLDNFKRANIEGAIFV
                     IWIDPPYDKEPEKRVKQIISSIKDEIEDMKDVVNIVKKYSDIDKGISENKINILIGLE
                     GLSHIGRNIDLLDYFYKEVGARHASLTWNEQNELATGCLGDENRGLTEIGKKAVNKME
                     KLGMIVDVSHLNEKSFWDLMSVASKPVIASHSNARSLCDAKRNLTDNQLKEISNTGGL
                     VGINSFRGFTNSNPKKQDLIHLVDHIDYMVNLIGIEHVSFGFDFSDYLGKETIGSFTG
                     NASVPSVDGLESTHTAQNIVVELENRGYKKKDIELISSGNFYRLFKDILK"
     gene            37307..38260
                     /locus_tag="KOU88_002725"
     CDS             37307..38260
                     /locus_tag="KOU88_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBK3212594.1"
                     /translation="MKKRYLVIGIIILSYFSLFIGAEDINIMHIFAKNQHKLMIFIMS
                     RIPRLISILIAGVGMSIAGLIMQQISKNKFVSPTTGATIDAAQFGIVICMLLVPTASI
                     FTKTIIAFVFSLVGTFTFMKIIGKLQFKNIIFVPLVGIMFGNIIGSMTDFIAYKYDLS
                     QNVSSWMQGDFSMILKGNYEILYITIPLIILAYIYANKFTVVGMGMDFATNLGLSYKR
                     IVNIGLIIVALVTVCVVVTAGNIPFIGLIVPNIVSLYMGDNIRASIWYTGLLGAIFVL
                     ICDIFGRIIIYPYEISIGLTVGVIGSILFLYLILRRNVNEA"
     gene            38250..39206
                     /locus_tag="KOU88_002726"
     CDS             38250..39206
                     /locus_tag="KOU88_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBK3212595.1"
                     /translation="MKLSLNQKIYFVSILLFISIALFIIYGIDMNHLEYALSQRIPKI
                     FAMVLGGGCIAFTTVVFQTITNNQILTPSVLGLDSLYVMIQTIIVFIFGSSSSLIINE
                     NYNFIINVAMMIGASLLLYKTLFEKNKNNIFFLILVGMIFGTLFKSATTFIQVMIDPN
                     EFLALQTSIMASLNNINTNVLLIAFIIIIAIIPFIYDEIKYLDVLSLGKEQAINLGVD
                     FDKAVKKMIILIAILVSISTALIGPMTFLGLLLANITREIFKTYKHTYLISGSMLIGM
                     ITLIIGQFFIQHVFKFDTTLSVVINFIGGIYFIQLLLKGANR"
     gene            39203..39958
                     /locus_tag="KOU88_002727"
     CDS             39203..39958
                     /locus_tag="KOU88_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3212596.1"
                     /translation="MIEIKNIFKRYKNKNVVDDVSFSIEKGKITSFIGPNGAGKSTVL
                     SIVTRLIGGDGGEVIIEGKSLTNYSNKELAKKIAILKQSNNITLKLTIRELVGFGRFP
                     YSEGNLTKEDENYIDEAIEYMKLTDIQHKYLDELSGGQRQRAYIAMVIAQDTEYILLD
                     EPLNNLDMNHSVQMMKVLRSLCDELDKTIVLVMHDINFASCYSDNIVALKNGKVKKVG
                     RTDEIVNEKVLEDIYEMNFNIKNINGNRICIYF"
     gene            40050..41015
                     /locus_tag="KOU88_002728"
     CDS             40050..41015
                     /locus_tag="KOU88_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3212597.1"
                     /translation="MNKKAAIVAAVAIIGLVTVFALGGSKKNESKTSGNSNNTMKITH
                     NLGETDVKLNPKKVVVFDYSALDTMDALGVAENLVGLPKASLPASLEKYKDGKYADLG
                     GLKEPDLEGIKSANPDLIIINGRQEDFYEQLSKIAPTISTSKDDKKYLESVKNNIDKI
                     AKIFGVEEKANQEFSKIEKKIETLNKKVTDKNLNALTIMVNEGNLSVFGEESRFSILY
                     NSFGFENKDKNIKESSHGQNITFEYIAKQNPEVMFVIDRGIATGSDVKESSTAKSVLN
                     NDIIKSMDAYKNDNIIYLDSPTWYVNDGGLTSLNKMIDDASKAVN"
BASE COUNT        16005 a         4259 c         7150 g        13791 t
ORIGIN      
        1 tatctgcgga taattttatt ataattatga aatatataga agaagaagat ataacaaaga
       61 ggttaaaaac tatatttgaa gaattagact tgtttaataa taatcaagaa gaaaaatata
      121 agttagtttt aagttgtgga atctatttta tacttccaga agatagagat atcaactcaa
      181 tcatagatag ggctaatata cctcataaaa tggcaaaggg aggacataaa agttcatatg
      241 cattttatga taataagatt catgaccaag agataaaaga aaaagagatg gaaaatacaa
      301 tgttttcaag tctagaaaat aaagaattta ttatatactt acaacctaag atagaactta
      361 atacaggaga gatacaaggt tcagaagcac ttgttaggtg gaaacgtcct gataaagggc
      421 taatacctcc aaatgaattt atcccatttt ttgaaagaaa cggttttgtt ataaatttag
      481 atttatatgt gcttgaagaa gtatgtatat accttagaaa atggattgat gcaggaataa
      541 atccagttac tgtttcagtt aatgtttcaa ggatacattt atattgcaat aattttatag
      601 aaacatacaa aaatataatt gataaataca atatacctgc aaagtatata gaacttgaat
      661 taacggagag tatcatattt gataattttg atattttaat tgatataatg aataatttaa
      721 aaaaaatagg atttttaata tctatggatg attttggttc agggtactca tcattaaata
      781 tgttaaaaga aattcctatg gatatcttaa aacttgacca aaaatttatt atggaaactt
      841 ataatagtaa aagaagcaaa ataattgtta ctaaagtaat agaaatggca aaagagttgg
      901 gtatgaaagt catatcagaa ggagttgaga cagaagaaca gtttaaactt ttaaaagaag
      961 taaagtgtga tatggcacaa ggatatttgt ttggaaagcc aatgccaatt gaagaatttg
     1021 aacatttaat tgtatctaac ttggtaagag ggtaattaat ctgtaatata aagaatttaa
     1081 taaattgtgt taaaaatgga ctctaatgta gtgttcattt tttttgtaaa attttttata
     1141 cttttactaa aaagtaattg acatatactt tgtattatta tattattgta ttaacaactt
     1201 aatacaataa tataataagg aggcatgaac atggaatggg aacttgataa taacaaacct
     1261 atatatatac aattagtaga acatttaaag ttaaaaataa tttcagggga aattaaaata
     1321 ggatctaaat tagaaacagt gagagcacta gcagaagatg cggaagttaa tccaaataca
     1381 atgcaaaagg ctctaacaga acttgaaaga caaggtttag tttatagtca gagaactaaa
     1441 ggaagatttg taacagatga taaggaaaaa ataaaagcta tgaaagagga aatagctaat
     1501 gtggagataa atacattaaa agtaacctta gaaaagcttg gatatgatag agatgaaatg
     1561 ctaaaactta ttacagaaaa tctgaaagga gaattataaa atggataaaa atataagcaa
     1621 tgtttctcaa gatggaatag ttgaatttaa aggtgtaaac aagagttatg gaactaagaa
     1681 tgttttaaaa aatattgatt taaatatacc aaagggaaaa atagtcgggc tgttaggacc
     1741 taatggaagt ggcaaaagta caatgattaa gctaatgaat ggattattac agcctgataa
     1801 tggtgaaatt atgataaatg gaatgaaacc atccatagat actaaaaaaa tagtttcata
     1861 tttaccagaa agaacttatt taaatgattg gatgaaggta tcagatttac ttaagttttt
     1921 ctatgatttt tatagtgatt ttgatgttag aagagcaaat gagatgatta aaagcttaga
     1981 tattgatgta aatgaaaagc taaagacaat gtctaaagga actaaagaaa aagttcaact
     2041 tattttagta atgtcaagaa atgcgagcat atatatattg gatgaaccta taggtggtgt
     2101 tgacccagct gcaaggtcat atatacttaa gactatatta aaaaattatt ctgaagatag
     2161 tactttactg attgctaccc acttaataag tgaaatagaa aacatatgtg atgagataat
     2221 attcatatca aaaggagaaa tagtgttaca aggagacgtt gaagcaataa gagaagaaaa
     2281 aggaaaatct atagatgcat tatttaggga ggaatttaaa tgttaggtaa attattaaaa
     2341 tatgagttaa aagcaagtgg aagaatattt ataccgttat atatagccat attgatagta
     2401 gctgtattta atggaatatt tatgaataca aatatacttc aggtacaggg aataggaata
     2461 ctagtattaa caagtctttt tatggcatta ggagttttaa ctattgtagt tacaattcaa
     2521 aggtttagaa aaaatctttt gggggatgaa ggttatttaa tgtttactct tcctgttagc
     2581 actagttcac ttatattatc taaatgtata acagcactta tatacgctgt acttagtttt
     2641 atagttgcag tattcacttt tggagttctt atgctttttg gtacttctgg aattttacta
     2701 cctgaaattt tagatttgtt taacactagt tttaaatgga tttctgaaaa ctttttagat
     2761 attttattat tagtagtagt aatgtttatt tcatattcat catttatttt gttattatat
     2821 acatcaatct caatgggaca attgccaaaa ttcaataaac atagaaacat agtggcattt
     2881 gcttctttta tagctataaa tatagtaata tcaattgttg gagatgcagt tggaagcatc
     2941 ttaccaaatg aagatacaaa tatggtatat catctttatc agagtcctag ttttatgctt
     3001 gcaatacttg gtagtcttgt agttgcaata gcgttatttt tcgctacaaa atttatatta
     3061 gataaaaaat taaatttaga ataaatgttt ttatatggag ctatcttttg agtaatgtta
     3121 aaagatggct cttattattt atgtagttaa ttcatgtata taatatgaat agtgttttat
     3181 ttctagttaa atatatacat atgttgtata atgatattgc gtgtaaaaat ttgtaagaat
     3241 aactatacac tttatataag ttatatcaag aaaatttaaa aatatatgga tttgagggag
     3301 aagatatgaa aagttataca aaggctaagt ggagtgtttg gggtataatt acattttcat
     3361 ttgttttagt attattttta aggatgtcaa ctgctgttgt ttcagacaat ttagcaaatg
     3421 agttaggttt taattctata caaatttcaa atatagcatc cttttgccta tatgcatatg
     3481 catttatgca aatacctgca ggaattttga ttgataaata tggagcaaga aaaattagca
     3541 gtcttggaat aataatggca agtttagggt caattttatt tggtttgatt caaagtatag
     3601 aattagcata tatttctcgt gtaattgtag gggcaggaac atcagtaata ttactttgta
     3661 ttttaaaaat tcaagggaga tggtttaata agtcagaatt tgcttctgca acagctaaat
     3721 tttcatttgt aggaaattta ggtggagttc ttgctacttt tccacttgtg tttttgtctg
     3781 aacttgttgg ttggagaaat tcatttttat taatcggtat aattggtgtt gtaattggat
     3841 gttttatgta tattattgtt agagatacac caaaagagta tggattcaat gtagatactg
     3901 aaccctatga aaagtcagag aaggttaata ttgttgatgg tattaagtct gttataaaga
     3961 acaaatcaac atggtataat tcaatgataa tgttctcttt tgttggtctt acaagtgcat
     4021 ttataagctt gtggggagta agatacataa tggacgttta tggtgtgagt aagagttttt
     4081 ctgcgtttat agtatcattt tttacatatg gatttatatt tggttcaata attatggatt
     4141 ttgtatttgc taaaataagg tctagcaaat ttaatataat aaaatttgga gcaatgatag
     4201 atttgtttat atggattgta attgtagttg tataccaggt aaaaccacca attatagttt
     4261 taccaatatc attctttatt atgggatgta tagttatgtc acatctacag gtttttaatg
     4321 atgccaagta taaaaataaa gaaatttatt ctggactggc aactagtgtt attaatactt
     4381 ttgaatttat aggaagtgga attattaatt tgattatagc tatctcttta caagtaaatt
     4441 catataatat agttgatgga tataaaaaag gttttgtagt atttatagta ctaagtatta
     4501 taactatagt atcatctcat ataggggtaa aaaatgatga ttttaaggct atatagtgtt
     4561 ttattaatag tttaatttag tattatattt tgcatatata taacaaatag tttgcatttt
     4621 cctaatatgt ataattggaa tataaatctt gtttactatg tacaaatggt attgtattat
     4681 attaaataga aaataagaac tttaaactat aatattggtt ctaaaatata aggtaaggag
     4741 ttttttatgg atacgacgaa aatagatgat ataagcaagt tagatttaaa taatttagat
     4801 attaataaga tggatatggg aggtataatg gaaagtctgc tagaatgggc tactacaagc
     4861 ggagtaaaac ttataatagg catacttata ctttctattg gatttaaaat aataaaaaaa
     4921 tttgtaaacc atgttatgtt attacttagt aaaagagata ttgatttaac tttaagaaag
     4981 tttttaaagt ctcttctttt gagtgtactt aaagttgccg ttataatcat tgttctggaa
     5041 tattggggaa tgagtttgtc cagttttgct gctgtgatag catcagcagg ggtagcaata
     5101 ggtttggctt tacaaggtag tctatcaaat tttgctggag gatttattat actattgatt
     5161 agacctttta aagtaggaga ttacgtagaa gcagcaggtc atggaggaac ggttgaacaa
     5221 ataggtcttt tttatacaca attggttact ccagataata aacagatact tatacctaat
     5281 ggttctgtat caaatgatag tctaataaac tattcagcaa agaatactag acgagttgat
     5341 ttgactttta gtgtagggta tgaagatgat atactacatg ttagaagagt acttaaagat
     5401 attgttaata atcataaatt aataataaat gaaccagaac catttatagg agtagtagaa
     5461 catggagata atgctattaa atttgcaact agagtttggt gcaagacaga agattattgg
     5521 acaatttatc ttgatttact agaagaggtt aaagttaggt ttgacgaaga aggaattacg
     5581 attccatatc ctaaaatgga tttaacggta aaagaattaa acaaaattta attttttaat
     5641 atagtgttta aatttaagaa tatcatatag atatacttat aaggtttgta aaaaattaat
     5701 aagtactgtt attttgtaag taaaaatata aaaaaatggg agtgtctcaa aatgaacttt
     5761 ttagttcatg aggcactctt tttgtacgaa ataaaatata tttttattat ttcaacaatg
     5821 aaaaagaggc ttgtttccat tttgagacag tataattttt atgtaacttt aattttagta
     5881 aatataaagt tttaaaattg ataaaatagg aggaattttt aatataaaag ggtaaataaa
     5941 gggtttagag ggcataatat agaataaatt aatatattta aggagggttt ttatgtgtaa
     6001 aaaaacgtat ttattagtgg taagtatgct tatagcgggt ttattaactg catgtagtgg
     6061 gagtccaact aaggattcag gacaagcaca agataataca aaaaaggagg caaatgcatc
     6121 aaataacgct ttaaaagatg aaaaaaataa tgaaaattta atggaacaag attttaaagt
     6181 gccatacaca gatgcaataa acatatttaa agataaatat aaggatgctg atatagtaga
     6241 tttaagtctt gagagagatt taaataaatt tgtttatact gtggaaggtg tagatgataa
     6301 taatgaatat aagatgaaaa ttgatgctaa tacaaaagat gtattagaag ataaaacaga
     6361 aaagttggat tcagaagatt taaatggagt tgctagaaaa gaaaaattag atttaaatga
     6421 cataatgaca cctcaacaag ctatggaaat tgcattaaaa gaacaaaatg gaatagttaa
     6481 agaatggagt ttagacaaag atttagatgt tactttttat aaaataagaa tagataaaga
     6541 taaaaatgaa tatgacataa aagtagattc taaaaaggga actgtattga aggtagaaaa
     6601 agaagattag aagatttaaa ctatctttaa aataatttct tttttgaata aattttgttt
     6661 aaaatataac aagcagggta taaagagact aaataactat tttaggagga gtacggtatg
     6721 tcattgaaat cactaaaaat aaaagaaaat ttatattggg taggttcgct tgaccctgat
     6781 ttaagagtat ttgacataat tatgtataca ccttatggaa ctacttataa ttcatatgta
     6841 ttaaaaggaa cagaaaaaac agttttattt gagacagtta aagataagca ttttgacaat
     6901 tatattgaaa gattaaatga tttaaatata gattttgaaa aaatagacta tattgttgta
     6961 agtcatactg aaccagacca tgcaggaagc gttgaaaagc ttttggattt agctaaaaat
     7021 gcaaaagtag tagcttcaga aacagcaatt aaatatctta aggaaatcgt aaacaaagac
     7081 tttgaatatg ttgcagttac agatggagat acattatcaa ttggggacaa aactttagaa
     7141 tttttctctg tacctatgct tcattggcca gataccatat acacatatat aaaagaggat
     7201 aaaactcttg taacatgtga ttcatttggt agtcactata gtaatgataa gatagtaaat
     7261 acacttgatg aaaatgaaga aaaggattac ttggatgctt taagatacta ttatgattgt
     7321 ataatgggtc catttaaacc atctatggta actgctatag aaaagataaa agatttagat
     7381 atagatactg tatgtccagg tcatggtcca gtattaactg aaaatcctag aaaaattata
     7441 gacctttatt acaactggag tgtaaatgaa caaataaagt tagaaaaaga agttacaatt
     7501 tgttatgttt ctgcacatgg atatacaaag attatggcag aagctataaa agcatatatt
     7561 gaaaaaaata gcaactataa agtaaattta tttgatgtaa tagagcataa gcaagaagat
     7621 attttggcaa aaatagcagt atcacaaggt gtattatttg gaacaccaac aatattagga
     7681 gatgcgttaa agcctatatg ggatatatta atatcgttaa acccagttct tcatggtgga
     7741 aaagttgctt cagtatttgg ttcatatgga tggagtggag aaggtataga aaatgctatg
     7801 gagagaataa gtcagcttag aatgacagca gtaaaacctt ttgctgttaa ctttaaacca
     7861 tcaaatgaag agattgataa attatattct tatacaggta aattcctaga taagttaaat
     7921 tctacttttg gaagtaaaaa gaaaactaag aaatttaaat gtgtaatttg taatgaagtt
     7981 tttgaaggtg atagtgctcc tagtgtatgc cctgtatgtg gagctaagga agaccaattt
     8041 atagaagttg aagaagatga agttactttt agaaaagata ctgatgaata tttcgtaata
     8101 gtaggaaatg gagcagctgg tttttatgca gcagatgcta taagaaaaag aaataaaact
     8161 tgtaagataa ctatgatttc taatgaagat gagttgactt actatagacc tgcactttct
     8221 gatggtataa atgaagaact tggttcagat ttctacatgg aagataaaga ttggtatgat
     8281 aaaaataata tagtagtaat attaggaacg aatgtagata aattagatga agtgaataaa
     8341 actattatag tgaatgatgg agctattaaa tttgataagc ttgtaatagc tacaggaagt
     8401 agaaacttta taccaccaat taagggccat gatttagaaa atgtgtttac tcttagaaat
     8461 ataaaagatt tatatagtgt aaaagaagca ctagaaaaat ctaagaaagt tgtagtgatt
     8521 ggtggcggtt tattgggact tgaagctgca tgggaattta gactaaaagg attagaagta
     8581 gtagtagttg aagccatgga tagcatacta tcaaaacaac ttgataaaga aggtagtaaa
     8641 atattagaac aatgtgtaag agatacagga atagatgtaa gattgggtgt agcagttgat
     8701 ggtattgaag gtgatggaaa agctcaaaaa gttgtattta aagatggaga tagtgtcgac
     8761 tgtgatatgg tagtattttc aattggtgta agagcaaaca ctcaaatggt tcaggataca
     8821 tctgtaaaaa ttgatagagg tattgttgta gataagacat tacagacaaa tgttaaagat
     8881 atatatgctt gtggagatgt tgcacaagtg ggaaatatta gtttagcaat atggccatct
     8941 tcagtagaaa tgggaaaaat agcaggggca aatgcaagtg gagataattt gacatttgaa
     9001 agtgaagtat atccagtttc attagatgca atgaatgtaa aagtatttag tattggtaat
     9061 atacaaaatt ttgataaaga aatttcatca aaagatgaag gtcaaagaat atataaaaaa
     9121 ttatttatga aagatggttc attagttgga gctatactta taaatgattt aagctgtact
     9181 gttaaattga taagattaat atctgaaaaa ggtgattttg aggatattat gaaggctgat
     9241 atactataat ttaaatacat taaaataaaa aggagttgtc tcaaaattga tttttttcta
     9301 atcaaatttt aaattcaact ccttttttga atttttatat aaaataacat ggaaatttta
     9361 gtaatgtctg tggttacata cataggttta attgtttttt atatggattg tctctggtat
     9421 aataaattga attgtgtttg actgatagat atttttattg aaagttaata cctgttatgc
     9481 gataataagg acgtgttagg ggagttttta taataacaat taatctcagt ttttgtgttc
     9541 caatagtagc atcaacacat tctgatgtag tagttctttt cttataaaaa ttagttacaa
     9601 atatgcttgt aattatttga tatgtaaatt taccaatatt ataaatgatg acctcgataa
     9661 taaggagagt gaaaaataat ctatgaacga aaatattttg attgtggatg atgaaaaaga
     9721 aatagcagat ttaattgaag tatatttaaa aaatgaaggt tttacagtat acaagtttta
     9781 tacaggtaag gaagctctag aatgtattga atctaaaaat ttggatatgg ctattttaga
     9841 tattatgctt cctgatattg atggatttca tatttgccag aaaattcgag aaaaatacta
     9901 ttatcctatc attatgttaa cagctaaaat tgaagatata gacaagataa tgggtttaac
     9961 cataggtgct gatgattata taacaaagcc atttaaccct ttggaagttg ttgcaagagt
    10021 aaagacacaa ttaagaagat atatgcgata taataattct tatgaacaac agtcgataat
    10081 tgttaatgag tatgatatta aaggattgat tatcaataaa gaaacacata aatgtagttt
    10141 atttgggaaa gaagtagcat taacaccgat tgaattttct attctttggt atttatgtga
    10201 acatcaagga aaagtggttc cttctgaaga attgtttgaa gctgtatggg gagaaaaata
    10261 tcttgataat aataacacag ttatggctca tatagggcga ttacgtgaaa aaattcatga
    10321 accttctaaa aacccgaaat ttataaaaac tgtatgggga gtaggttata caattgaaaa
    10381 gtaaaaatat taaagtcaat cctgacttta ctcaagtgag aaataaaatt tttatgagaa
    10441 cagctttaat ggcatttata gccattattt tcatatggat tttatattct tttatattgt
    10501 atggtaagtt ttctatctgg atagtatcat tctttgaaaa tgcttttcgt atggaatata
    10561 aagctgcatt gaatttatat cagcagattt tccgtaatag catggagctc ttcatgatac
    10621 tagctatggt gattgtgttt tttataatat tccgggttta tttaaattgg tttacaaaat
    10681 attttagtga aataaatcaa ggtattgact ctcttatcaa agaagatgtt ggagaagtgg
    10741 ctttatctcc agagttattg gcaatagaaa agaaaataaa ctcaattaaa catatacttg
    10801 aacaacgtaa atttgagaca caaatggcag aacaacgtaa gaatgaactt attgtttatc
    10861 ttgcacatga tttaaaaaca ccacttacat cagttatagg gtatctgaca ctacttcgag
    10921 atgaaagtca gatttctgaa gaactgcgaa aaaaatattt atctatttcg ttggataagg
    10981 cagagcgtct tgaagattta attaatgaat tctttgaaat tacaaggttt aatttatcaa
    11041 atatatcact tgaatacagt acagtaagct taactcgtat gcttgaacaa ctaacatatg
    11101 agtttaaacc tactttgatg agtaagaatt taaaatatac actgaatgtt acaccaaata
    11161 tgatgataag gtgtgatgtt aataaaatgc aacgtgtatt tgataactta ttacgaaatg
    11221 ctgtttatta tagttttgaa gatactacta ttgaaataac agctgtacag gaggatgatt
    11281 atataaagct taaatttata aatcatagca atacgattcc agaggaaaaa cttgagcgta
    11341 tttttgaaca attttacagg ttggatacat ctcgtaattc aaacagtggt agagctgggt
    11401 tgggacttgc tatagctaaa gaaatagtgg agcttcataa cgggacaata acagctcata
    11461 gcgagaacaa tataattatc tttaaggtta ttattccgat tgtaggaaat ttgtaagaat
    11521 ttaagtataa aaaaatagga aattctttag gataaataaa taaagagcac tcttgttatt
    11581 gatataatta ctgtatcaaa acaagagtgc ttttattttg atacagtaat tatatcaata
    11641 gaaaaatgtg aaaatatatt atgtggaaca gatgcaattg taagtgaagg ttgattggat
    11701 ttgaaataga aaaagtattt taacatgttt ctgtagattg tataaaaata aataaatcaa
    11761 caaaggagaa tcaaagatga ataataaaaa aattgcagtt atatttggtg gaaactcaac
    11821 agaatatgat gtatcattac aatcagcttt tgcagtactt gagaatttga atacggaaaa
    11881 atatgatatt ataccaattg gaattacaag ggagggtaat tggtatcatt atattggaga
    11941 ttataataat atccagaata acacttggtt tgaaagggat actgatataa ttccagttat
    12001 tgtttcgcag aaccgtgtca aaaatggtat tattgaattt ttaattcctg atgctgtttc
    12061 tcagaatcat attccaaata gtgctattga atcatgtgaa aatgatatta aatacactaa
    12121 acttgatttt gtgtttcctg tactgcatgg aaaaaatgga gaagatggaa cagtgcaggg
    12181 gttatttgaa ttggcaggta tacaggttat aggatgtggt actctttctt cagcattatg
    12241 tatggacaaa gacaaatcac ataaacttgt tcattcagaa ggtattaaag taccaaaatc
    12301 aatattacta aaatactcag ataaatttaa tgtggctgaa ctgtcaaaag acttaactta
    12361 tccattattt ataaaacctg tgcgtgcagg ttcatcattt ggtattagta aaatttataa
    12421 aaaagaagag ttacaagtag cagtagactt ggcttttgaa catgataatg aagtaataat
    12481 tgaggaaaat attgatggtt ttgaggtagg gtgtgcagtt ttaggaaacg atgacttact
    12541 tgttggaaga gtagatgaaa tagaattgtc aaaaggattt tttgattata cagaaaaata
    12601 tacattgaaa agttcaaaaa ttcatatgcc agctagaatt gatttggatt gtgagaaaag
    12661 aatacaagag acagcaaaaa ttatttatag aactcttgga tgttctggat ttgctagagt
    12721 agatatgttt ttaactccat ctggtgaaat tatttttaat gaagtcaata caattcctgg
    12781 ctttacttct catagtcgtt atccaaatat gatgaaaggt attggattgt cttttgaaga
    12841 aatattggac aagataattg aggtgtacat aaaatgatga ataatatttt attagataaa
    12901 aataaagaag ataaaatgac aaatactatc ttattgacta aagataaagt ttatgatggg
    12961 aatctaattc tagtaaatgc ttttttacca gttaaaacat ctgaagatat agatttaatt
    13021 cctgtagata caaggtttcc aagtattctt atgaaacgtg aagctacaaa cattttacaa
    13081 aatattttaa aaagtatatg tggaataaat gaaatagtac ctgtaagtgg atatcgtact
    13141 gcagaggaac aacaagatat atattcaagt tctctgcgtg acaatggaaa agactttact
    13201 aaaaagtttg tagcacttcc aaatcacagt gaacatcaga cagggcttgc tattgattta
    13261 gggttaaaga aagaagttat agattttatc tgccctgaat ttccttataa tggtatttgt
    13321 aatgagtttc gtaaggcagc actacattat ggttttatag agcgttatca gtgtaaaaaa
    13381 gaagaaataa caggaatatc tcaagaacca tggcattttc gttatgtggg atatccgcat
    13441 tctgagatta tcaataaaat gaatctcgct cttgaagaat atatagaata tattaagaga
    13501 ttttcgtata caaattgttt aaaaatagaa gataaagaaa aaattataga aatcttttat
    13561 gtgcctattc atactaaaga agaagtgaga atctctatac ctgaacaatg tgtatatcaa
    13621 atatcgggta acaataagga tggttttatt gtgacatttt ggagaaatag aaaggactaa
    13681 gaaatggagg aacaagaatg attaggaata aatcttatgc agggcttgat tattttagga
    13741 ttatagctgc attacttata attgcaattc atacatctcc attattatca tatagtaaaa
    13801 tggctgactt tgtgttaact agtataattg ctcgtattgc tgtgccattc ttttttatgc
    13861 tatcaggctt ttttctaatt tcaacatata attataattg taataaactg aaatcttttc
    13921 taaaaaatgt attatttatt tacgggatag ctattgtaat ttatattccc ttaaatattt
    13981 acactggata tttttccatg aataatttag tgcccaatat tattaaggac attgtatttg
    14041 atgggacttt atatcattta tggtatctac ctgcatcaat tattggtgca agtattgcat
    14101 actttcttgt aaaaagacta ggtttaaagt actcactagt aatcactatt gttatttatg
    14161 taattggtat gtttggtgat agttattatg gttttttaga aaaaatacca ctattaaaga
    14221 atttatatgg gtatattttt gaagtatcag attatacacg aaatggtata ttttttgcac
    14281 ctgtattttt catacttggt ggaataatat ctaataaatc taattatatg tcaactaaaa
    14341 atagcttgat tggatttctt atatcattct tacttatgtt atgtgaggga atgtttttac
    14401 ataaactagg ggtacagcgt catgatagca tgtatattat gttattgcca tgtatgtatt
    14461 tcttatttac agccttaaca tttttgaaag gttctcgagc taggttattg cgaacatcat
    14521 cattaattat ttatattata catcctatga tgattgttgt tattcgtatg ttttctaaaa
    14581 tattcggaat acaaactgtc ttggttgaca atagccttat tcattatata gtggtaagta
    14641 tagcatcttt tatagcttct ataattatta tattgattct taaacctcta aaaaaagact
    14701 tgaaaggaga acataaggta aataccaata gagcttggat tgaaattgat ttaaataatt
    14761 tggaacataa tgtaaagatg atacaaaaag ctatgccaga agattgtgaa ttgatggcag
    14821 ttgtaaaagc taatgcctat ggtcatagtg cttttgaagt agcgacttgt gcaaaccaaa
    14881 taggtgtaaa agcatttgca gtagcaacaa tagatgaggg gattgattta cgtcgatatg
    14941 gaatactagg agaaatattg attcttggat atactaaccc aataagggca aaggaacttc
    15001 ataaatacaa tcttacacag agtgttattg accttaatca tgctatctct ttaaacaaac
    15061 agaaatacaa cataaaatca cacattaaaa ttgatacagg tatgcacaga ctgggttttg
    15121 atgttaatga tgtgaggtca attttaaagg catttaaatt aaaatactta gatatatgtg
    15181 gcatatttac acacttgtgt gtttcagata gtctgaaaga tgaagatgta gactttacaa
    15241 ataaacaaat tgaatgtttt tataagttaa ttgattttct gttaaaaaaa ggtataaaaa
    15301 ttcctaaagt acatattcaa agtagttatg gtttttttaa ttatcccaat cttaagtgta
    15361 attatgtaag aattggaatt gcattatacg ggatattaag ttctccaaat gatacgacta
    15421 aattgcaact tgatttacga cctgttttat ccttaaaatc acaagtaatt cttattagaa
    15481 aaatacaaaa agatgatagt tttggatatg gaagagtctt tattgcaagc agagatagcg
    15541 taattgctat attatctatt ggctatgccg atggtatacc tagaaattta tcctgtggaa
    15601 aaagttacgt aataataaat ggttgtagag cagcaatagt gggtcgaatt tgcatggacc
    15661 aacttgctgt tgatattaca gatataccta atgtagaagt tggtaatacg gcaataataa
    15721 taggaagaga taatttatct gaattatctg cttctgaagt tgcaaataac tcatgtagta
    15781 tatcgaatga attattgagc agagtaggaa gaaggttaaa tgttataaag aagtaactca
    15841 attaaatagt aatatttgtt gtactgtgta atttatttta ctctgactag acatttttag
    15901 taatattatg tctaatatat attttttata acttacatga caatttaagt tataaaaagg
    15961 tgatgtttca gatttttatt ttgaaacatc accttttttg ttataatata taataaaata
    16021 attatacctt aactgtaaac ttatatagat tatttacttt ttaatattag attcattttt
    16081 tgagattggt atataataaa catatagagt atataataat agttaaagtt aaaaaagggg
    16141 aaaagcaata tgcagtatat acaagaacta cttgatttga ctcaaaatta ttgggtgtta
    16201 gccacaataa tcggcttatt aagtgcattt atagaaagct ttataccagc cttaccactt
    16261 gttgctatag ttacagcaaa tgctgcaata caaggattat ttattggatg tttgttatca
    16321 tggattggct caggacttgg gacaacttca ttattcttat taataagcag atttaatgat
    16381 agtaagcttt ttaataagtt gagaaatagt aaaactgaaa aagcaataag ttggatggat
    16441 aaacagggat ttaagttatt atttatagcg tatgcctgtc catttatgcc cggttgttta
    16501 gttactatcg catcagcttt tggtaaaaaa gatttaaaag attttgtgcc agcaatgttg
    16561 gcaggaaaat ttgtaatgtt tatagttata agttacgtgg caagtgatat agaaggtttt
    16621 ataacaagtc ctttaaagat agcatcattt atattattgg tgtttttgtc atggaagatt
    16681 ggaaatagag taaataaaaa tcttgaaaat cataattatg atttccatca taaaaaacat
    16741 cacaatgata aagatgataa aatgatttag cttgtacgaa ataaaacgta tcttaaaatg
    16801 atttagtact aaattatttt aagatacgtt ttattttttg tattaaggta caaaattttt
    16861 agttcttttg taaactaaaa tatataaaac ttatttatac ttagttcaaa atattgttat
    16921 ttattttttc tacaactata ataaaatata aaattgatat ccaatcaaaa aaataactat
    16981 gaaatttaat agcttagata tgaatttttc tgtttttgag ttagttttta taggtagtaa
    17041 agaaatgttt atggtaatgg gataaaacaa ttcaatacct tctttagtaa taaggtcaag
    17101 acacaagtga gatagatatc ctattataaa cccactggac aaacatgaga aaactatatt
    17161 attgttagtg aagattgtca gagatttaaa aaaactataa ataagtaata aggcaattag
    17221 actgtgagta aaccctctat gtctaaacct acttccaaat aatttgtata ttaacataaa
    17281 ttttttactt atgtaagaac ctctcatatc tatatctgga aataaagaac ctaaatatgc
    17341 aaaataaata taaattataa ttaatactat tttatatgca atatcgtatt taactaggta
    17401 tagattgttt ataaagggga gtatcaaaag tgcgaatata taacctcccc tttcatgtgt
    17461 ttcttttatc atataaaaat cctcctgaat cgtcactata aacattatat tggtaaattt
    17521 agactatctt ttattatatt atatagcaaa cataagtttt tttcaaaagg attttaatat
    17581 ttaattaatc ttgagatttt aaatttttgt aattttctaa agcaccattc caatttacta
    17641 cattaaacca gttgtcaatg tattcatttc ttctattttg atattttaaa tagtaagcat
    17701 gctcccaaac atcaagtcct attataggag ttaggttttt acttacaggg ctatcctgat
    17761 ttggagtagt cataatagat aatttgccat ctttagtagc tacaagccaa gcccaaccag
    17821 aaccaaagac atctaaagca gatttttgga actcttgctt aaatttttca aaagaaccaa
    17881 agtctctatc aatagcttct tttaaagatt cagaaggtat ggttttttct ggcgtcatta
    17941 tatcaaaaaa gaatttatga ttataagctc cacctgcatt atttcttaca gttgtagcaa
    18001 tatctttagg taaagaatct aaattttgca ataattcaca taaagaataa ttataaagct
    18061 caggatattt ttcaagagca gcatttaatt tatcaacata agcttgataa tgcttatcat
    18121 gatgcagttt cattgtttct ttatctatat aaggttcaag tgcatcatat gcataaggta
    18181 atggtttaac cttaaatttg ttattttcag gtgtaaaagc aaatgaagtt atgcactgtg
    18241 agattataaa taaagacata ataactggta ttaatatttt tttcttcata aaaatcacct
    18301 cctaatatag tatttctaga aataaaaaaa atatgaaata ttaacagata atttataaga
    18361 atttaatagc aatttcattt taaattgaat aagttttaaa gccaaagaca aaactatgaa
    18421 atatagaata agactaaagg acagaaagga attttgatta tatggacggc aatatttcaa
    18481 tttattataa aggtgatata tctaaaaaag aagatattaa atttaaaata aaagaatctg
    18541 taaataatac aagactttct agtagaatag agtataagga tgaggaaaaa acttttgatt
    18601 ttgaaagatt taatgtaatt gatgctattt atggaaataa accatttgaa aaagatggaa
    18661 aagttattgt ttttaatgga aatatatata actatcatga aataaaagaa gaattaatta
    18721 aaaaaggaca caattttact acaaatgatg atattgaagt cttattggca tcttatatag
    18781 aatttggtaa gaattgtgta cataagatta aaggaatgtt caactttata atctatgata
    18841 gagaaaatga aagtatattt ggagcaagag atttatttgg gataaaacca ctttattata
    18901 taaataagga aaatgcaata attttttcct cagagtataa gtttttactt gaatatatga
    18961 aaaatttaaa tataaatgaa agaagcttac aaagttattt ttcatttcaa tatgtacttc
    19021 ctgaagatac tatgatacaa ggaataaggc tgataccagc aggtcactat tttagggtag
    19081 aaaatggtat actatcttta aagagatata ataaacttga gtttagaagt agtacaaaat
    19141 ttttttatac taaaaatcac ttaggcaata gagatgtgaa cgaggatgat ataagaaata
    19201 tagtagtaga ttcaatagta actcatatgg aagaggagaa agaaattgga acatttttgt
    19261 ctggtggaat agattcatct attataacta ctgtggcttc acaaattaat ccaaatataa
    19321 aatctttttc tgcaagcttt agtgtcaaag gatatagtga attagaagta gcaaagaaaa
    19381 cagctgataa gttaggtata gaaaatatcc agattaatat aacacaagat gaatatataa
    19441 aatcattacc gaatgtaatt tattctttgg atgaccctat agcagaccct tcagaagtag
    19501 gtctttattt cttaattaaa gaggcaggta aacatgttaa agtagcattg tctggagaag
    19561 gagcagatga attatttgga ggatataata tatataaaga gtatagtact atgaaatcag
    19621 ttgtcaattc acctacttat attaaaagta tattaggaag agtttcagaa cttatgccaa
    19681 acataaaagg aagaaattat ctttatagag ctacaacacc attagaaaaa agatatatag
    19741 gaaatgcaaa agtttttgaa aacagcgaag taaaaagatt cttttttaag tataaggaaa
    19801 agaatatata tgaatacctg ttgtctaatt tgtatagaga tgcacaaaaa aataattacg
    19861 attatataag taaaatgcaa catatagatg tgaatacatg gcttcaaggc gatatacttc
    19921 aaaaaattag caaactttct acagctgagc aggttgaact tagagtacca tttttatata
    19981 aagatgtatt tgatgtagca aaaaatttaa gaatggagca aaaaataaat aagaataata
    20041 caaaagtttt acttagagag gcgtttagag aaatagtccc agaacatgtt gttcaaagga
    20101 aaaaattagg atttccaact ccaataagag tttggttaaa agattctcta ggggatattg
    20161 taaaggaaac tatttataat tcaaatgtag atgaatttat agataaaaaa tatgcaataa
    20221 aacttttaga tacgcatctt aaaggtcata gagataattc gagaaaaata tggactatat
    20281 ttacattttg tctatggcat caattattta ttgagcataa aaatgtcgag tattaatact
    20341 gttttcaata ttaatcagag ggcaaaagca tgcaatgttt tcaccctcct gattattatg
    20401 gaataggata agtagaattt tgattgatta gtttactatc tcaataaaat tattggcaaa
    20461 tattttgaca agactacttt caacagctaa atttaagttt tgtccatcat catatccagc
    20521 ggaaatcaat cctagcaagt ttccaaacat atccaaaaga gctcctcctg aactaccact
    20581 agagattgga gctgtaaatt gtatcatttg aaccgtttca aaatcacgaa aagctgagat
    20641 aattccatct gaaactgtat taaaaagacc taaagggctt ccaattgcaa ctattttttg
    20701 acctctcaca ggttttttac tgactttaac aggtattggc ttgcattttc tattaacctt
    20761 tatcacagct aaatcataat ctgaatggta ttttataatt tggtaagatg tataaacttt
    20821 atcatcattt tcaaatctaa ctaaaaatga atacccatca ttgactacat gaagattcgt
    20881 aagtatataa ccttcattat ttattactac tccagaaccg ctcttaaacg gtttattttc
    20941 gttattgcac acaacaatca taacaacaga agctgataac tttgcaaggt cttcataaga
    21001 aagttctact tcctcatctt gtacaatttt tttagatgtt agatttgtgt tattaagtgt
    21061 atttttagag ttaggtttat tcgtagtagg agaagtctta ttggtatttt cactgtaatt
    21121 tatatttgta atatgccttt caaaaggtat ttctaatata tttggagtct tcctagaaag
    21181 ttcaaataga gtagaaaatt ttgaacattc aggatataaa tcaagaatat ctttatttgg
    21241 atttatatat aaaatatcac acccaagttg tgataaaaaa tataagaaaa aaagttcttg
    21301 ccttttaata tttccaaagt atactatctt tggtgaaata gtagtcttca ccttgttata
    21361 aaataattta ggtagaaaat agtctatcca acacaaaagt ttaactgcaa agtttttgat
    21421 gatagaggat gtacaatttg gcatacttgt ggaaaataaa tctaaagtat ttttaaatgc
    21481 aatcttttta gtccaattta aagtgtcatt ttctatttta catggaaagt cgatattata
    21541 taaatcccaa ctgttaaact tagaactatc ataaatatta aaaattttaa gcatcttatc
    21601 tgtttgttct ttgtcaaaat ttatttttag attgtttaat ctaatatagg gaattgtagg
    21661 attattaaaa aaataagtat ctatattttt aattttttct atgtatttat caattgaatc
    21721 atcaacacct atatatcttg taaagtagac ttctttaata tatgaagaac tcttattttt
    21781 ataggtagta tcagatataa attcaattag aggttcagta gactttttta ttgaaatctt
    21841 taatggttta atagtacaaa tcatattttt tctcctataa taagatgata taatctatta
    21901 taaaacaact taaaacaata tagtacaata attttgtagt ttcaaaataa aatatgtact
    21961 tgtttatata aatgatatat aattacatat taaacatagc ttttatgcat ttaataaagt
    22021 atgtaaaatc tatgtaaaaa gtaagaaata taaacatttt tttaattata ttttaaaaat
    22081 atcaagcaag ttttcttcac aaatgaataa aaaatgttat aatatgatta aagaaaaaga
    22141 taaataatta gcaagatttg tttagctaaa attaacaagg gagcgataaa ttatgggtat
    22201 aacattatca aaaggccaaa aggttgattt aactaaagga aatccaggcc ttaaaaatat
    22261 tttagtaggt ttaggatggg atactaacaa gtatgatggt ggatttgact ttgatttaga
    22321 tacagcagca tttttaacag gagcaagtgg aagtgttact aatgatggag attttgtatt
    22381 ttacaacaat ttaaaacata catctggagc agttgagcat ctaggagata acagaactgg
    22441 cgaaggtgat ggagatgatg aacaaatagt tgttgattta tctaagattc ctggagaaat
    22501 aagcaagatt tcttttactg ttacaattca tgatgcaaca gaaagaagac aaaattttgg
    22561 acaagtaagt aattcttata taagaatagt agataaagac acaaatgaag agttaataaa
    22621 gtatgaatta ggagaagatt ttagtataga aacagctata gtagtagctg aaatatataa
    22681 gcacaatgga gaatggaagt ttaatgcact aggttctggc tttgaaggtg gtcttgctgc
    22741 attatgtgga aactttggaa taaacttata atttcaacta taacaataaa ctaaaggggg
    22801 atattttcca tggctatagt attaaaaaaa ggacaaaaaa tcgatttaac taagggaaat
    22861 ccaggtctta aaaatataaa acttggacta ggatgggata caaattcatt tgatagtggc
    22921 tatgattatg atttagatgt aagtgttttc atggttggag aatctcaaag agttgaaaaa
    22981 gatgaagatt ttatattcta caataactta aaacatccat ctggagcagt tgaacactta
    23041 ggtgataata gaactggtga aggtgatgga gatgatgagg aaatattagt gaatttagag
    23101 acaatgccaa agcatataca aaagatagct gtaacagtta caatatatga ggctgctgaa
    23161 agaagacaaa attttggaca agtaagtaac tcatatataa gagtattaaa ttctgaaaat
    23221 gatgaagaaa tattaagata tgacttaggt gaagaattta gtatagaaac tgcaattaca
    23281 gtatgtgaga tatataagta taatggagaa tggaagttta gtgcagttgg agcaggattt
    23341 gaaggtggct tagaagcact ttgtagaaac tatggcttaa atgtttaatt taagcaatat
    23401 aatatattaa atataaataa cctatacaaa taatgtatag gttatattat ataaaatttt
    23461 gtggaggttt agtatgtcga ttaatttatc aaaaggtgat aaaatagatt taaaaaaatc
    23521 taacccagga ctgagtaaca tacttgtagg tctaggatgg gaccctgtgc aacaatctgg
    23581 cggaggtttt tttaaatcgt tatttggtgg aggacaagct gatatagatt gtgatgcatc
    23641 tgtatttatg cttaatcaag aaggtaaatt aagtggaata aaagatttaa tttattttgg
    23701 aaatctaaaa agtgcctgta aatcagtttt gcatacagga gacaatctaa ctggtgaggg
    23761 tacaggtgat gatgaacaaa tcctagttaa tttggataaa gttccatcaa atattcataa
    23821 attattgttt gtagtaaata tatacaattg tgtagataga aaacaacact ttggaatgat
    23881 agaaaatgcc tatataagag ttgaagacca aggtaataag aaagagatag caaaatacaa
    23941 tctatctgat aattattctg aaaaaactac tcttatagta ggagctatat atagaaaaga
    24001 tggaagttgg caatttaaag caattggtga aggaacaaaa gatgcgggtc ttaaagaagt
    24061 aatgcaaaat ttagacagga ttgagtgtgc atatggaatt taataatgat atcaaatatt
    24121 ataatgtaga taaagaagaa gttacaaaag acttatctgt taatcctgaa aaaggtttat
    24181 cagaatcaga agtcaagact agaagagaaa aatatggttt gaatgaattt actccaaaag
    24241 aagagggtag tttttgggat gatttaaagg aaagtttaag tgaaccaatg atagttatct
    24301 tgattattgc agcagtagta agtgcagtaa ttggggaaac tcatgatgca atagggattg
    24361 taggtgctat agcaataggt atagcaatag gtatgattac agaaggtcgt tctaagaaag
    24421 cagcagaggc tctttctaag ttgactgaaa acatagaagt aaaagtattg agagatgggg
    24481 aagtacatca aatttctaag agtgaattgg taccaggtga tatagtatat attgaaactg
    24541 gtgacatggt acctgctgat ggtagactta tagaaagtat aaaccttaaa attagagaag
    24601 atatgttaac aggagaatct gatgacgtat ctaaaaagtg tgatgtagta gtttctatgg
    24661 aagagataga atctaaagga gcagtagtag tacaggagcc aatacctgca aaacagataa
    24721 atatggtgtt tggtggcaca cttgtagctt atggtagagg agctctagtt gtaacttcaa
    24781 ttggagataa tagtgaaatg ggtaaaattg ctcaaaactt atcagaaaca gatgagcaaa
    24841 ctccacttca gataaaactt ggaaatttag gtggtttgat agccaaagtt tctagtgcag
    24901 tagcaggatt actatttata tttatggttt tccaaatgat aagtaagaat gtattaaatg
    24961 tagatatgtc tggaatatta ccgtttttag aatcaataga cccagttaaa acagcattta
    25021 cagtatgtgt tgcgttgata gttgcagcag tgccagaagg tcttccaact atgataaata
    25081 tgacacttgc aataacaatg caaaaaatgg ctaaaataaa tgcattggtt actaaaaaag
    25141 aagcttgtga aacgataggt tctgtttctg taatatgttc agataaaact ggtacattaa
    25201 ctgaaaatag aatgactgta gaagttgcat atgttgatgg cagatatatt gaaagttcag
    25261 aagaggaaat aaatagttat tttgaagaaa actgtatgat aaactctaca gctgatgtag
    25321 agcacaatga tggtgatatt aagtatttag gaagtgctac tgaatgtgca ttgcttttat
    25381 attacaaaaa cgtagattat agacaagtta gaaaaaattc taatatagta gctcaaaatc
    25441 cttttacttc agattcaaag agaatgactt ctgttatagg tcaagataat catcatgtac
    25501 tattatcaaa aggagcacca gaagtcttac ttgaattatg ttcacatatt caaagaggaa
    25561 aagacatagt tccattaact gaaaatataa aacatgagat tttagaagaa ataaagaaat
    25621 tgcaaataaa atcaatgaga actttagggt ttgcatataa agaaatctca caagctgaag
    25681 aagaagcagc agtaactgct gaaagtgatg ctatgaatgt aagtgcaatg gaaaacaatt
    25741 tagtatttag tggttttgtt ggtataagag acccacttag aaaagatgtt atagagtctg
    25801 taaatacagc aaataaagct ggtgtttctg taaaaatgct tacaggagat aatataaata
    25861 cggcaagagc tataggtgaa gagttaggcc tattaaaaaa taatatgaga gtggttgaag
    25921 cttcatatat agatacttta gatgatgaag aattaaaaca agagatacaa agtatttcaa
    25981 tcgtggcaag aagtaaacca gatagtaaaa tgagaatagt ttcagctctg caaaagagcg
    26041 gagatgttgt tgcagtaaca ggtgatggta taaatgatgc tccagcactt tcaaaagcag
    26101 atgttggtat agcaatgggt atatctggta cagaggtatc taaaaacgca gcagacataa
    26161 ttttaactga tgatagtttt agtaccattg taaaaggtat taaatggggt agaggaattt
    26221 atgataactt ccaaagattc gttcaattcc aattaactgt aaatgtaatt gcatttttag
    26281 tggctataat atctcaagtt atgggacaag agatgccatt tactacaata caattattat
    26341 gggtaaacat cattatggat ggaccaccag cactagcatt aggtttagag ccagttaggg
    26401 accatgtgtt aaatagaaaa cctgttgata gaaaagccaa tataatttct aagtcaatgg
    26461 tgtatacaat agtattaaat gcattttata taacagcaat actaatgtta caatctacat
    26521 ttaatttctt aggagttgat gaagcgcata agggaacagt aatgtttgcg ttatttgctt
    26581 ttagtgcact gtttaatgca tttaactgta gagagtttaa tgcagatagt atcttcccta
    26641 attttacaca taacaaatta gcactacaaa taatagtgtt gacaggaatt gcacaagtaa
    26701 tatttactca gctattccaa gatttcttta actctgtagc aatggatttt atgacatggg
    26761 taaaagtttt atgtgtagca gcaagtgtaa ttgtggttaa tgaagttgta aaatgtataa
    26821 taagactggt aaaaccaaaa aagactgctt aaaacaaatt ttttagaaga aaacagactg
    26881 actcaaaata tgaattttgg gtcagttctg aataaacatt taaattggga ggatagttat
    26941 gggtgactca aaggtatttg aaaaaatatt ctccagccaa tcagatagag gaaattacac
    27001 tccttcaaag ggatatctaa gttattttat ttcgtatatt ggtttagaag atgaagtttt
    27061 gtacaatctc gagatattta agacaaaaca aaatattgat agcaaaaaag atattgcttt
    27121 atttactgat gttatagcaa atcctagtga ttttgatatt ataaattatt ttaaaagtgg
    27181 acttcaaaaa tatagaacta gcatggaaga tgtagatata aatattttgg gatttgaaga
    27241 gattgattat aaaataaagc aagcaatgga tagagtgtta aaagaagagg aaaaagaatt
    27301 tactaatgat agagttaaac aaaattttat agtgaaaata atggcatgga taaaaattta
    27361 tatcggtgct ttagatataa ataaaaatga agctccaaaa gtaatatttt atggagatat
    27421 aaaaaaacat gaagtttatt tactcttaat attatacttg gcaggttttg atgttttata
    27481 tcttaatcca aattcaaaga gtaatataga tattttaaaa tcagaaagat acaatataga
    27541 gtttgaagaa gccaacataa tagaagaaaa aatttctttt gaagaaaggg ttattttagg
    27601 ggaaaaaata gataaaagtt ctgtaaaaaa agcttttact gttggggcag aagcatcaaa
    27661 gcgtataagt gaggaattgt taaatgatgc aggatttata aaaccttggc aactccaaga
    27721 tagaaaaata aaaaatctac ttctaagttc aactgttgat gaaatatcaa tatactggaa
    27781 tcaaccactt aaattaagac caggatttaa gtttaatgat gctattgtag aagctccaaa
    27841 ttttctttct aagattaatg gaatatataa cgataagaat gaatatatta agtttttaga
    27901 tttattaaga gattcggaaa gttcaacatt tattgaattt aatggagatg tagatagatt
    27961 ttcaaaagct tttacaagag aagcttttag tttatccttt ttattggatt caaaaggtgc
    28021 aatagataaa aactctgttt taaataataa agattattcc atatcaacac tagcattgaa
    28081 tcaacaaatt atgattttag agaaagtgga agagttgtta gaaggaagta tgtttttgaa
    28141 tggtttaagt ggagaagaca agataaaagg tctatttaca gtacttcaca tggataagaa
    28201 atttgttcat atgatgaaca atttcgatta ctcacttata aacccaaaat tgattatata
    28261 catgtacaag agtattgtat ttgataaaga aatagttttt cttatgcttt tacttagtaa
    28321 gattggattt gatattatca tattatgtcc aggaggagaa aacaatatag agaatgttat
    28381 aaataaccaa ttgattgatg tacacagatt ggataaaatg gtatatgacc ttaaattaaa
    28441 ttcgcttgaa aatgatatac ctttacttaa aaaaattttt ggaaagagga gacgatttta
    28501 gatggggata aatataaata gtttttcaaa agataagaac tctgtagagg ttactgagaa
    28561 tttgcctaca gcagttcaag aagaaaactt cgatataatg gaatatacaa ataataaaaa
    28621 aaatgaactg agaaagtcta aggaagttga ggcattgaca tcccttatag aagtagaaaa
    28681 tccagatacg attttacagt ttggtaggaa agcatctgaa ggagtagcaa gagtttctga
    28741 tagcctttta aatacaataa aattaaatag aaatgaagaa aattctaaaa tgctggttca
    28801 tttaactaaa ataatggaca agtttgattt agacgatttt caagaaacta aggaaccaaa
    28861 tttcgttcaa aaacttttca aaaaagctaa taatgccatt gaaatgatgt ttcaaaagta
    28921 tgaaacattg ggaggagaag ttgagaaaat tcaaattgaa cttgaacaat acgaaagaga
    28981 tatagcactt tctaataagc aaataggtgc tatgttaaat gaaaactttg agttttacaa
    29041 tgaacttcaa aaatacattg ttgctggaga aatggcaata gaagaaatgg ataatgaaat
    29101 actacctttc tttaaacaaa aatcagagac tagtggagac caaatggatg ttgtcaatta
    29161 tcaagaacta ttaaaagttt atgatatgtt aaatcaaaga gtctatgatt taaggatagc
    29221 agaaaatata gctatccaaa caatacctat gcttagaggt atgcaacata ataattatgg
    29281 tttaattaga aaaataaata gtgcatttgt cgtaacttta ccagtattta aacaatgttt
    29341 atctcaagct atattactta aaaagcaaga attacaagca aaatctctaa aagcacttga
    29401 tgacaaaact aatgaattat tgcttagaaa tgcacaaaat gtaagtactc aaagtgcaca
    29461 aatagctaga atggctggaa caagttctgt tcaaatagaa acattggaaa aaatgtacaa
    29521 tactatcaaa tctggtatag atgaaactat gagaatagaa gaaaacaata gagctttaat
    29581 taaggataat acaaagagat tggaagaatt aaatacgact ataatttata ataagtagta
    29641 ttatattaag ggctaatttg tataaagttg gccctttcta tgtatatgag gaggctagac
    29701 attgaaatat ttcgattata tctgcaaaga tgatttggag aaaatttttt tgaaggagcc
    29761 agaagatttt agtgctaaga ctgaaaaaga tgtgttgaaa tatgcactgg gcgctttttt
    29821 atacgttcca gctactcaat ataatatgat ttataagagt attatagggg atgttaaggg
    29881 agttagacca ttagctattt gtttagaaga tgctgttgga gtaaatggag agttggaggc
    29941 tatagaaaat cttagattaa ttttaaaaaa tattagcaat gaaagtataa ctaataaaga
    30001 tggaatacca ctaatttttg taagaataaa agatgtggag caactgttga gaattaaaga
    30061 gattataatt aaaaatagac attctataac aggaatatta attcctaaag caaattcgga
    30121 gttaatagaa aattgtatag aagctttaga ttctatgaat cttcaagata tgtatgttat
    30181 tccgataata gagacaaaag aatttatata taatgaaaaa aaagaactta gttttactaa
    30241 tttgtacaat gctattttaa gacataagtc aagaatatta agcattagag taggcataac
    30301 tgatatatta gggatgtatg gtataaggag agataagaac ttctctatat ataataattt
    30361 gatttgttct tcatttatat tagatataat cacatatctt caaagaccag agttagatat
    30421 acctataagt ggtggagtat cagaattttt tgatatgacg aataaggata taagaaataa
    30481 gtatatagaa gaaatattat tggataaata tcatggatta attggaaaga ccgtaattca
    30541 tccaatgcaa attcaaattg tacaagcgct atctacagta tcatatgaag attttactga
    30601 tgctttggat atactggata gtacagacag taagtatggt gtgagcaagg gtgtattagg
    30661 agagagaatg aatgaaacaa atccacattt tttatgggct aaaaaaacat tgattctatc
    30721 taaaatatat ggtgtattaa ataaaggagt agactatgaa gaattgctta aattttaatt
    30781 gtgagattga cattattgat aatccattga atttagaact aaatgatttt ttagacgtag
    30841 gaataagaaa taatagcaaa agacgttttt tgtttatctc aaagaaactc ggtaaacatt
    30901 tagcatgtaa gccaagtgag atggataatt tgggaaaatt aatggctaca atttataatg
    30961 aaaaaaataa ggaagaatca aatggtactg ttatagcttt tgctgaaact ggtacagctg
    31021 ttgggcatag tttttttgat tacttatgtg gagattatga atttattcat actactagag
    31081 agcagtttga cgagttagaa aatctggaat ttttagagga acattcccat gcaacagacc
    31141 agaatttata ctttggtatg cttaacaact ttaaatttgg agatgagata atattggttg
    31201 atgatgagat taccacagcc aatacatgca tgaatataat taggaaaatt caaagcattt
    31261 atcctaaaaa gaaatacact atatgctcaa tactcaattg ggtaagtgat gaaaatttaa
    31321 gtaaagttac tcgtttagaa agagagctag attgtaagat agattttgta tacttattta
    31381 aaggaaactt taaattttat atagatgaag atattatttc aaattacaac gataattata
    31441 gtattactaa attagagact atttcaagtg ataaagtaaa tttagtagta aatcatattt
    31501 atgttgattt agaagattat attggaaata agaaatatgt aaaatataca ggaagatttg
    31561 gaattaatag aagagaacaa tttagattaa aagaaatcgt taagagagaa agtaaaaaaa
    31621 taactatggc cagtaaagaa tctttaaaaa atgaaaaaga aaagattcta tttttaggta
    31681 ctgaagaatt tatgtatata cctatgctgt ttgcaaaaga aaaagaaaat caatatgata
    31741 tatactatca ttcaacaaca agaagtccaa ttattaatat tgataagaat aattatccta
    31801 ttaaaagtaa atttatgcta aagagttttt ataatataga tattcaaaat tatatttaca
    31861 atatagataa acataatttt tctaagtgtt atttatttgt agagctgaat aaaagtgaaa
    31921 attcttatct agaatttatt gatataatta aaaaaacaag tataaaagaa ttaactatag
    31981 tatgttgtag ctaaagtgtt ttaacaggat aaaatatatc acgattttaa gataggagtt
    32041 gagtcatatg agagatttta gcacgtattc taaagatgat gttatttttt tattaaaaga
    32101 tatatcaaat ttaattgaag aagaaggaaa taaagaaaga gaattaaaaa tacaaaatgg
    32161 tagacattat tcagaaatga taccaataga gtatgaagtt agtgaagatt atctgaattt
    32221 atatcatgag aaactaagag aaaataaaga taaacttgca ttttctatag gagttatgtg
    32281 tgaaaaaata attaaaaaaa atggaaatga tgtagtacta gtttcacttg ctagagcagg
    32341 aacacctatt ggtattttgg caaaaagata tataagaagc aagtataatg taagtttacc
    32401 tcactataca atctctataa taagagataa gggaatagat atgaatgcaa ttgaatatat
    32461 agtaaagaat catccgagct caaaaattca atttttagat ggatggactg gtaaaggaac
    32521 tatatcaaaa gaacttgaaa aagcatgtga tgaacttaat gttaaattta aaaaatattt
    32581 tgactcaaca cttgctgtat tagctgaccc tgctggatat tcaggacttt atggaattag
    32641 agaagatttc ttaataccaa gtgcatgttt aaattcaaca gtttctggtt tagtaagtag
    32701 aactgtacta agagaggatt taattagtaa aaatgacttt catggagcta agttttatag
    32761 acatttaaaa gataaagatg aatctatgaa ctatatcgaa actatagaag aatgttttaa
    32821 aaatcaattt aagaatatat ctgatgaagt tgaaaactgg gaaagtgaca ttataacaag
    32881 agatggatac tttgatgttt taaatataaa agaaaagtat aacataacag atattaactt
    32941 tatcaaacca ggtgtagggg aaacgactag ggttttactt agaagagttc cgtataagat
    33001 tcttgttaaa gacttaaatg ataaatcttt agaccatata ttcatattag ctaaggagaa
    33061 aaatgttgaa gttgaacaaa tggatttaaa agcctataaa tgttgtggaa taataaaaaa
    33121 tatgaaagat atttaggaaa tatattagac aggagaatat tgaatgattg ttttttcaga
    33181 tttagacagg agtatcattt actccaataa atttttaaat gctgatagta aatatgctaa
    33241 tatagaaatt tatagggaaa aagaaatatc ttatatatct ttagatacta taaatttaat
    33301 aaagcaaata caatattatg gtatgtttat acctacaact actagaacag tggagcaatt
    33361 taagcgtata gaatttaata aatatgggat ttattttcct tggagtataa cttcaaatgg
    33421 aggagttata cttaaagata atgaaatatt gaaatcatgg agtgaaaaaa tagataaact
    33481 aaaatctgat tatgagccca ttgaaagtat gattcataaa tttaaagact atttgaatgt
    33541 agatggaata actaatttta aagttgcaga agatacattt ttttatatag ttgttgattt
    33601 atcaagattt aatttggatt caatcaaaga atatacaaat atattggaat caaaaaattg
    33661 gaagttttat gtgagtggca gaaaaatata ttttatacca aaagaaattt caaaagaaaa
    33721 tgctataaaa tacttgacta aagaattagg aatagaatat ttttatgcag ttggagattc
    33781 tattatggac tatggtatgc ttaatatctc aaataaatcc tatgtattga agcatggtga
    33841 tataaataaa aatgaaatag aaaattcatt tatatcaagt tctttcaatg gaatgagtgg
    33901 aactgaagag atactatcta acattttaga tgagaactgc ctacttaata tataatgact
    33961 gatatataaa taataaacta gaaaaatctg aaataaatta tagtaaagtt tatcatacta
    34021 atttatttca gatttttatc aatttatatt taagtaagaa ctcaatatgt taaaatgaag
    34081 gtggagtcat tgcccagact gagatacata cctcatcatc ataattttca tacacatgtg
    34141 gtatagtact gttaaaataa aaactatctc cttcctccaa tagatattcc ttatttccaa
    34201 gtgttatctt cattttacct tttattatat agccacattc ttctccttcg tgtgtcacaa
    34261 attcactgtt tttgtgtgta tgaccatcta gtgtaacaag tataaattct atttttttcc
    34321 cagataaatt aggaacaaga agttcgtaaa attttgtaga atcattagtt actatttttt
    34381 ttcgattatt tttctttact actatatcag agtcttctct tccaatctct tcaaaaaaat
    34441 aacctatatt tatatcaaga gcttttgata ttttccacat tgctacaata gatggaacaa
    34501 ccatattacg ctcaatttga cttattaagc ctgtacttaa atctgaattt tttgctaaag
    34561 tagagatact tatattttta gattttctaa gagatctaat tttgcttcca acatctatat
    34621 tcattagata caaaccccct cagacatgat tataacatat aatttataaa gattaataaa
    34681 ataaaaaaaa agttttacaa tacaagtatt ttttatgcta tattgaattt tctgaaaaga
    34741 tgcattataa tagtattaat attcaatata ttgaatattg ataacgatat tttaatttaa
    34801 tgaaatggag gtaattaaga tgaagagttt tgtaagtcct gataatattt gggtattatg
    34861 ggcagttgta actggatggg cagcatttag tatttatttg gaacaaaagt acaattgggc
    34921 atcaaaagtg tcgggagcaa taatagctct tgtaggagca atgttattat caaatctaaa
    34981 tattatacca gtagagtctg ttgtatatga ccaagtatgg ggatatgttg ttcctttagc
    35041 catagcttta ttgttatatc aatgtaacat taaaaagata tggaaagaaa gtggaagatt
    35101 gctcattata tttcttgtag gttctgtagg aactgtactt ggagctatga ttggattttt
    35161 agcattaaaa aatgtagtac cagatttaaa tattgttgca gctatgatga caggttctta
    35221 tataggtgga aatgtaaact ttgctgctat gtcaggggcg tttgatgcgc caggagaatt
    35281 agtatcagca acagttgtag cagataatct tttaatggca ttatatttct ttgtcttaat
    35341 agctatacca tcaattggat tttttagaaa acattttaaa catccacatg tagatgaaat
    35401 ggaaagtata ggtataactg aaggagaaac agtagcagca aattattggg gaagaaaaga
    35461 aatatcttta aaagatatag caatagccat tggtagcgct tttataattg tcgcagtatc
    35521 tgtagaacta tcaacttggt ttaaagctat aataccatta tcaaatcctt ttttagcaat
    35581 gttaaatact ttatttggaa atcaatatct aataataact actttgacta tgttgtttgc
    35641 cacatttatg cctaatttct ttggtgatat aaaaggagca caggaattgg gtacattttt
    35701 aatatatata ttctttgttg tagtaggtgt tcctgcttca ataacattaa taattcaaaa
    35761 atcaccatta ctacttttat actgcggaat aatggtacta ataaacatgc tagttacatt
    35821 tatagttgca aaaatattta agtttagttt agaagaagct attcttgcat ctaatgcaaa
    35881 tattggtggt cctacaacag cagcagctat ggcaatatca aaaggatggt ctaagctagt
    35941 agggccaata cttatagttg gaacatttgg atacatagtc ggtaattatt ttggtctttt
    36001 agtaggaaat attttgatat aattttacgt gaaaaaaagt tgttttttag aaagattttt
    36061 atttaattgg aggttgttat gattttcgat ggacattcag atacttgggc agatgtaaca
    36121 ataagaaggc ttaacgggga aaaagatgta tttagaagaa tccatcttga taattttaaa
    36181 agagcaaata tagaaggagc tatttttgta atatggatag acccaccata tgataaagag
    36241 cctgaaaaaa gagttaaaca aattataagc tctataaaag atgaaattga agatatgaaa
    36301 gatgttgtaa acatagtaaa aaaatattca gatatagata aaggtataag tgaaaacaaa
    36361 ataaatattt taattggtct tgaaggatta agccatattg gaagaaatat agatttacta
    36421 gattattttt ataaagaagt tggtgcaaga catgcatcat taacttggaa tgaacagaat
    36481 gaacttgcta caggatgttt aggggatgaa aatcgtggtt taactgaaat aggtaaaaaa
    36541 gcagtcaata aaatggaaaa attgggcatg atagtagatg tgtcacattt aaatgaaaaa
    36601 tcattttggg atttaatgtc tgttgcaagt aagccagtta tagcttctca ttctaatgct
    36661 aggagtttat gtgatgctaa aagaaatctt acagataatc aattaaaaga aatttcaaat
    36721 acaggtggat tagttggaat aaatagtttt agaggattta ctaatagtaa tcctaagaag
    36781 caagatttaa tacatttggt tgaccatata gactatatgg taaatcttat aggtatagaa
    36841 catgtatctt ttggttttga ttttagtgat tacttaggga aagagactat aggttctttt
    36901 actggaaatg ctagtgtgcc aagtgtagat ggtcttgaaa gcacacatac agcacagaac
    36961 atagtagtag agcttgaaaa tagaggttat aaaaagaaag atatagagtt aatctctagt
    37021 ggtaattttt ataggctctt taaagatata ctaaaataat ataataaaga acttaaattt
    37081 ataaaatagt atatttatac aaataatatc tacatattta aattggcgtt cataatttat
    37141 taaattaaat tttaatgtta ctagaagttt caattctagt aacatttttt atgttaaaaa
    37201 cagatataga tatatattga caatgataat tattattgat aaactataaa agtgaaaatg
    37261 ataataattt tcattttaat taataaaaga tttttaagga gggagaatga agaaaaggta
    37321 tttagtcata ggaataataa ttttgtctta tttttcttta tttataggag ctgaagatat
    37381 aaatataatg catatatttg ccaaaaatca gcataaactt atgatattta tcatgagtag
    37441 aataccaaga ttaataagta tattgattgc tggtgtagga atgagcatag caggtcttat
    37501 aatgcaacag ataagtaaga ataaatttgt atcacctaca acaggtgcta caatagatgc
    37561 agcacaattt gggatagtaa tatgtatgct tttagtacca actgcctcta tttttacaaa
    37621 gacaataata gcatttgtat tttctcttgt agggactttt acgtttatga aaataatagg
    37681 gaagttacaa tttaaaaata taatctttgt accattagta ggtataatgt ttggaaatat
    37741 aataggttct atgacggatt ttatcgcgta taaatacgat ttgagtcaaa atgttagttc
    37801 ttggatgcaa ggtgactttt ctatgatact taaaggaaat tatgagatat tatatatcac
    37861 aatacccctt ataatattag catatattta tgcaaataaa tttactgttg ttggtatggg
    37921 tatggatttt gcgacaaact taggtcttag ttacaaaaga attgtcaata taggtctgat
    37981 aatagtagca cttgttacag tatgtgtagt cgttacagct ggtaatatcc cttttatagg
    38041 tctaatagtt cccaatatcg tatccttgta tatgggtgat aatataagag caagcatatg
    38101 gtatactggt ttacttggag cgatatttgt acttatatgt gatatttttg gaagaattat
    38161 tatttatcca tatgaaatat ctatagggct tacagttgga gttataggaa gtatactatt
    38221 cctttattta atattaagga ggaatgtaaa tgaagcttag tctcaatcaa aaaatttact
    38281 ttgtaagtat attactattc atatcaatag cactttttat aatttatgga atagacatga
    38341 atcatttaga atatgcatta tcacaaagaa taccaaaaat atttgctatg gtattaggtg
    38401 gaggatgtat agcatttact actgtagtgt ttcaaacaat tacaaacaat caaatattaa
    38461 caccaagtgt actaggttta gattcattgt atgtaatgat tcaaactata atagtattca
    38521 tatttggttc aagcagtagt ctgattataa atgaaaatta taattttatt attaatgtag
    38581 ctatgatgat tggagcttca ttgttattat ataagacgtt atttgaaaaa aataaaaata
    38641 atattttctt tttaatccta gtaggaatga tatttggaac cttatttaaa agtgcaacaa
    38701 catttattca ggtaatgata gaccctaatg aatttttagc tttacaaact agtataatgg
    38761 caagtttaaa caatataaac actaatgtat tgttaatagc atttataata attattgcca
    38821 taataccttt tatatatgat gaaataaagt atttagatgt attgtcgtta ggtaaagaac
    38881 aagcaattaa tttaggtgta gattttgata aagcagttaa aaaaatgata atattaatag
    38941 caattttagt ctcaatatca acagcactta ttggacctat gacattttta ggacttttac
    39001 ttgctaatat aacaagagaa atttttaaaa catataagca tacatacttg atttcgggtt
    39061 ctatgttgat agggatgatt acattgataa taggtcaatt ttttatacaa catgtattta
    39121 agtttgatac aactttaagt gtagtaataa attttatagg aggaatttac tttattcaat
    39181 tactattaaa gggggcaaat agatgataga gataaaaaat atatttaaaa gatataagaa
    39241 taaaaatgtt gtagatgatg tctcttttag tatagaaaag ggaaagataa catcttttat
    39301 aggaccaaat ggagctggaa aaagtacagt actatcaata gttacaagac ttataggagg
    39361 tgatggtgga gaagtaataa tagaaggaaa aagcttgact aattatagca ataaagaatt
    39421 agcaaaaaaa atagctattc ttaaacaatc taacaatata actttaaagc ttacaataag
    39481 agaattagtt ggatttggaa gatttccata tagtgaaggt aatctaacta aagaggatga
    39541 aaattatatt gatgaagcaa tagaatatat gaagttgact gatatacaac ataagtattt
    39601 agatgaattg agtggaggtc aaagacaaag agcttatata gcaatggtaa tagctcaaga
    39661 tacagagtac atattacttg atgaaccact gaacaatttg gatatgaacc attccgtaca
    39721 gatgatgaag gtacttagaa gtctttgtga tgagttagat aagactatag tattagtaat
    39781 gcatgatata aattttgcat catgttattc agataatata gttgcattaa aaaatggaaa
    39841 agttaaaaaa gtaggtcgta cagatgagat agtaaatgaa aaagttttag aagatattta
    39901 tgagatgaat tttaacatta agaatataaa tggaaatcga atctgtattt atttttaaaa
    39961 tattgtatat gaaaataaac ttgctatatg attttttata aagtttttaa attaaaataa
    40021 agattaatag gagagaggaa aatattgata tgaataaaaa agcagcaata gtagcagcag
    40081 tagctattat aggattagtg acagtgtttg cattaggtgg aagtaaaaag aatgaatcaa
    40141 aaacatcagg aaattcaaat aataccatga agataactca taacttggga gaaacagatg
    40201 taaaattaaa tcctaaaaaa gtagtggtat ttgattattc ggctttagat acaatggatg
    40261 cattaggtgt agctgagaat ttagtaggac ttccaaaagc gagtttacca gcatccttag
    40321 aaaaatataa ggatggcaag tatgcagatt taggaggatt aaaagaacca gatttagaag
    40381 gtataaagtc ggcaaatcca gatttaatta taataaatgg aagacaagaa gatttttatg
    40441 agcaattgtc aaaaatagca ccaacaataa gtacaagtaa agatgataag aagtacttag
    40501 aatctgttaa aaataatata gacaaaatag caaaaatatt tggagtagaa gaaaaagcaa
    40561 atcaagaatt tagtaaaatt gaaaagaaaa tagaaacttt gaataaaaaa gtaacagata
    40621 aaaatttaaa tgctttaact ataatggtaa atgaaggtaa tttaagtgta tttggtgaag
    40681 aatcaagatt tagtatatta tacaatagtt ttggatttga aaataaagat aaaaatataa
    40741 aagaatcaag tcatggacaa aatattactt ttgaatatat agctaaacaa aatccagaag
    40801 ttatgttcgt tatagataga ggaatagcta ctggcagtga tgtaaaagaa agctcaactg
    40861 caaaatctgt tttgaacaat gatataataa aatctatgga tgcatataag aatgataata
    40921 taatatattt agattcacca acatggtatg taaatgatgg tggtctaaca tctttaaata
    40981 aaatgataga tgatgcttca aaagcggtaa attaataatc cgatataacc aaaatgtatt
    41041 ttttataaaa tgattatcaa ataaactagg agtttttaag aactcctagt ttattttttg
    41101 cataaaaaag atgtagttta aacaataata ttatctataa taagataaat ctattcaaaa
    41161 tctaataaaa tatgaagtta tactagacaa aaagaataac tctta
//
LOCUS       DAFAZV010000039        40907 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.039, whole genome shotgun sequence.
ACCESSION   DAFAZV010000039 DAFAZV010000000
VERSION     DAFAZV010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 40907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40907
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.039"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..952
                     /locus_tag="KOU88_002729"
     CDS             <1..952
                     /locus_tag="KOU88_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK3212598.1"
                     /translation="AGVSKSTVSRYLNNKDISDSTKEKIKTIIDEYGYEPNAFAQSLR
                     AKKTYFIGIITPCLDSFVKSKIMMAIDEELKELKYTSLIINTNRKIRSEIDSISKLAS
                     LKVDGIILIGTEITKEHKNEIEKLDIPIVVVGQKVDGINSIVNDDYGAGYKMGQYIAN
                     KGYKNIVYLGVDESDISVGLNRKNGVLNGLKDKGYDAKVFYTDFDQETSIQRSGEMLE
                     SENPDIIICATDNIAIATMKEINKRGKSIPQDISVAGFGGYDVLSIISPKLTTIKFEN
                     KNAGKVAANTIVNLIQERKEPLLKEIKFELIEGESTINKN"
     gene            1121..1269
                     /locus_tag="KOU88_002730"
                     /pseudo
     CDS             1121..1269
                     /locus_tag="KOU88_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423822.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIB"
     gene            1288..2769
                     /locus_tag="KOU88_002731"
     CDS             1288..2769
                     /locus_tag="KOU88_002731"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBK3212599.1"
                     /translation="MYKEPKYRTILESTKEELNKLRNISLNDKYKPLFHIHPQHGLLN
                     DPNGLSYYNGKYHVFYQWYPYDATHGMKHWAYVSSDDFVNWNREDVALIPIESYESHG
                     AYSGNAIEVDGKLHMYYTGNIKYSAEDRYAYQNLAIMNKDGKITKYENNPIVSEIPKG
                     YTGHVRDPKVFKRKDKYFMLLGAQTSDKKGVIIVYESKNSIDWNFKGELNVKNIDEDF
                     GYMWECPDYINIDEKDILIFSPQGVEPKGFDYQNIYNVVYAIGNMDLDNLTFEIDTMK
                     ELEKGFDFYAPQTFIKDSQIILFAWAGMGEVLYPTDKNKWAHCLTVPRKLNIKNNKLL
                     QMPVDELIKLRYDETSGQNTIKNNINIIENNENVYELNINIKNIDSNKFGLELFSSQD
                     EGVKLEFNKLGNIVTLDRSNFKKVFGVEYGTNRKEYINIDENTNIKVLADRSILEIFI
                     NEGEVVFTSRIFAKENSNQIRVYSDKIVEYEYTKFKLKQGIEL"
     gene            2795..3766
                     /locus_tag="KOU88_002732"
     CDS             2795..3766
                     /locus_tag="KOU88_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HBK3212600.1"
                     /translation="MKKVISIGEALIDFIPNQNGGKLKNVSEFRRVAGGAPANVSAVV
                     AKLGGKSSFISKLGKDAFGDYIIDVLNEVNVNTDYVLRTSKANTGLAFVSLKEDGNRD
                     FSFYRNPSADMLLEADEVKKEWFNNCHILHFCSVDLIDSPMKLAHKKAIEYALESNSI
                     ISFDPNIRLPLWDSEQSCKKAISEFLPFAHIVKISDEELEFITGENDIEKSLHKLFVG
                     NVELVLYTKGKDGVDAYTKKVKGMCKGVKVNAIDTTGAGDSYIGSFLYTLLYKQITLN
                     DIKEMKQETLNEYLEFSNYYAARSTTIKGAISSYATKEEITEFIKNL"
     gene            complement(4022..4624)
                     /locus_tag="KOU88_002733"
     CDS             complement(4022..4624)
                     /locus_tag="KOU88_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3212601.1"
                     /translation="MEVCILMGSPKKKGNTAAILKPFIEELENYNSNIEVIWLYDCKI
                     EPCIACKKCQDNLFDFGCYCKDDVQKIFKKILMCDLIVFATPIYSWYCTSPMKALLDR
                     LVYGMNKYYGNEKGPALWAGKPVALITTCGYRPEKGADIWENGMKRYCKHSQLKYIGM
                     LVERDLGKPNFMNKEKEEHSRQFAKQIYYILDNSIEVDNC"
     gene            4905..6116
                     /locus_tag="KOU88_002734"
     CDS             4905..6116
                     /locus_tag="KOU88_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-dependent decarboxylase"
                     /protein_id="HBK3212602.1"
                     /translation="MYSNEDYKFIEENAPCYIYDETNIIEKCKELKNNILGFDFLYSI
                     KTNPYNKIVKSIAEQGFGADASSTNEVMISSECGVSKDDIYYSSPGKTEIDIETVLDK
                     CIIIADSITEIELINKISKKHNQKVKIGIRINPDFTMDDDSAKSSKFGIDIEDMSSVF
                     KMLSMCDYVSVVGIHIHIKSQVLDFEKLGHYYEKCFFIALNLNKSKYINIEFINFGSG
                     LGVAYDNLRENPLNLKELSKLTQKIAFTNSNTLKSRLLIESGRFIVCKSGNYYVKIVD
                     IKVSRGKKYLIVKNGLNGFMRPIISNLIENITCGVELEGQEPLYTSNHAFSLSVLNNL
                     KEEEYVNVVGNLCTSLDVIANNVKLKKANIGDLISISNAGSYSYSLSPLLFSSYEFPK
                     QYYKRKDGYIE"
     gene            6184..6381
                     /locus_tag="KOU88_002735"
     CDS             6184..6381
                     /locus_tag="KOU88_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter"
                     /protein_id="HBK3212603.1"
                     /translation="MELWKRNLFVCWIGMFFSSIGMSQIAPILPLYIKQLGVTDVSLI
                     QQYSGIIFGCTFVVAAFFSPI"
     gene            6415..7386
                     /locus_tag="KOU88_002736"
     CDS             6415..7386
                     /locus_tag="KOU88_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3212604.1"
                     /translation="MLLRASIGMGIVIFTMAFVQNVYQLLGLRILQGVFTGYATACTT
                     LIATQTDKNHSGWALGTLATASTTGSLIGPTVGGYIESILGLKSTFIITGGLLFVSFI
                     ISILFVVDNFKPKEIKESISIPKEQLNILPNKFLIASIFVTTFITQLALYSIEPIVTI
                     YISQLTNFASNVALIAGLTFSASGLANLLAAQKLGKMSDKIGPQKVLLISLLWAGIIF
                     IPQAFVKTAWQLMLLRFLLGLSVAGLNPSVNSLLKKIAPEEYVGKIFGYNASAQYIGC
                     SSGAFLGGQISAHLGIRTVFFSTSLLLFMNALWMYKFTGLFIKDKTK"
     gene            7573..7950
                     /locus_tag="KOU88_002737"
     CDS             7573..7950
                     /locus_tag="KOU88_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3212605.1"
                     /translation="MTISKIPQAELKVMKFIWEKNDTVTSKETIEAMERKYGWKQTTT
                     LTLLSRLVKKHFLSAEKIDRYTHYTIVVGHKEYLSVETKDFLSNIHDNSLQSLISALH
                     DDEVVDKDMLDLFESHFKNLEEE"
     gene            8481..9140
                     /locus_tag="KOU88_002738"
     CDS             8481..9140
                     /locus_tag="KOU88_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBK3212606.1"
                     /translation="MLDAFITIVSSIIEIWSCKKVFDYTSQSKTDLKKLNMYFLFSVF
                     LIISSLYINIGANSRILICIFVMFVFYKSNYKVNIYKCLVISFFYWLILIGINGLSML
                     LVATVSNLDNMNVLLSGSLYRYEAIFLGKIMLGILLYVYKASFKNFKISKKEIYICIP
                     MIANLLSFFVLYDYIINLVKISPERRTAFLVIVLLLILSNISIFVLIHIILKIKIRKI
                     R"
     gene            9434..9775
                     /locus_tag="KOU88_002739"
     CDS             9434..9775
                     /locus_tag="KOU88_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator"
                     /protein_id="HBK3212607.1"
                     /translation="MKEENFINVEYEDKRFSINSKEVLYIEKQEYEVKIYTESANYEV
                     GENAPCIRKLLKEENFFKCSNSYIVNLDKCEFYLSNNCIFVNNNFIRILGSERKKKLK
                     KKLEKLYDYED"
     gene            9926..10339
                     /locus_tag="KOU88_002740"
     CDS             9926..10339
                     /locus_tag="KOU88_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1653 domain-containing protein"
                     /protein_id="HBK3212608.1"
                     /translation="MIELKNNLGISERKLKYPCIYKHFKGKYYATMGLSKAIDDIENI
                     CEIYGKENLIQNRNKYKLVIRHTEREEDIYVYRDLDGNFYHKKEEDTNDLVLYKTLYD
                     DTGIFARPLDMFLEKVDTDKYVNSIQEYRFEEVYK"
     gene            10541..11182
                     /locus_tag="KOU88_002741"
     CDS             10541..11182
                     /locus_tag="KOU88_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK3212609.1"
                     /translation="MGNTFYIVRHGQTDWNILGKTQGHGNSDLTPQGIEQAKELSEDI
                     GKYSIDYIFSSDLGRAMQTAQILGDKLNIEVQKTEALREMGFGVWEGLLIKEIQKDYS
                     DIYATWRNEPHLVNIPEGETLKIIKERVDAFIKELNEKYDNKNIILVTHSITLRVMLL
                     SFLESGMENIYRIKQDNTALNIVEFKDYGPVIVKMNDTSHIKNHVKINNSALE"
     gene            11206..12459
                     /locus_tag="KOU88_002742"
     CDS             11206..12459
                     /locus_tag="KOU88_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK3212610.1"
                     /translation="MSKVIVVGGGASGMMAALSASKNNNEVILVERNGELGRKLRATG
                     GGRCNFTNNREIEDFFDKVVSNKKFLYSSFYTFTNKDLISYFESRNLEYKIEEENDHK
                     VYTKNDKSIEVIEVLNKDLLNHNVKIMYNKKVIDIITEEIALKDDSNKDKSKYLIKGI
                     ILDNGDKILGDKVIISTGGVSYSKTGSDGSMYKILKKHGHTLNKLYPALVPLTIEEKW
                     IKDLQGISMKNVEISCKIKKRKISKSGDMLFAHFGITGPCVLIMSSYINKIIEKEKVE
                     LNIDFLPNLSTDEISSIIRAFPNKNVLNNLKQILPQNFLKEIFSLLSLVDKKASDLSK
                     ADEIRIIEYIKNMKLTCNGTTGINTGMVTSGGISVKEINSSTMESKLVKNLFFTGEVI
                     DIDAETGGYNLQIAFSTGYLAGISV"
     gene            12505..13155
                     /locus_tag="KOU88_002743"
     CDS             12505..13155
                     /locus_tag="KOU88_002743"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBK3212611.1"
                     /translation="MGNLVIAVDGPAGAGKSTIAKIVAKKLNINYIDTGAMYRAVTYK
                     CLKSGIDVNNEKEVIQIAENSDIDFKDNNIYLDKEVINEEIRTIEVSNNVSNVAKIKE
                     VRQLMVEVQRKIRMKSSVILDGRDIGSYVFPDADYKFFLVATPEERGNRRYKELCNKG
                     YNTTLEEVIEDIIRRDEIDSNREFAPLVKANDALEIDTTGKTIEEVVEEVVSKINL"
     gene            13206..13802
                     /locus_tag="KOU88_002744"
     CDS             13206..13802
                     /locus_tag="KOU88_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBK3212612.1"
                     /translation="MNFYRFVINIFKGFSKIFFKYEVIGAENIPDRGNIVIASNHKSN
                     LDPIFLAAAIENREIAAIAKKELFKVKPLGFILKKLHVMPINREKPDVSTIKTILRSV
                     RDGYVLGIFPEGTRIKGDSFGKAKAGLSVFTIKSKSKVVPVSIISKYKLFSKVIVYIG
                     EPISFEEHFKEKLSNDDHERISQEILEVIKQNYFKYSK"
     gene            13815..14654
                     /locus_tag="KOU88_002745"
     CDS             13815..14654
                     /locus_tag="KOU88_002745"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBK3212613.1"
                     /translation="MNIKIAKNAGFCFGVKRAMKMAWDEVEKNDSGIYALGPLIHNKQ
                     AVAKYEEKGLKTVNEIDTIPNHENMIIRSHGVPENIYKEAKDKKLKIVDTTCPFVKKI
                     HTVVSEYHNKGYEIIVIGDMKHPEVIGINGWCENSAIIIKTLEQMENMEFDNSKKYCL
                     VAQTTINPELYISIVNKLSDKLEEIVFNDTICSATKTRQESAKELAKEVDCMIVIGGK
                     HSSNTQKLVKVCEDLVPTFAIETKDELDVNTLKKYKNLGITAGASTPNWIIEEVVTFL
                     ENL"
     gene            14899..16053
                     /locus_tag="KOU88_002746"
     CDS             14899..16053
                     /locus_tag="KOU88_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic efflux protein"
                     /protein_id="HBK3212614.1"
                     /translation="MEMLISASEEAFLHVGSMIGFFILLFGYINYKTSGNFTNIISKN
                     RKFQPLIGALIGAIPGCGGSLAIMPLYINGKLSFGAIIASLIASMGDAAFVLISSNIK
                     MYFFVTIVSTITGIITGQLVDYFKLEEKLGLKNRRKSDKYDISKNNSKENKEQHNHDE
                     IILDTLAKSHGNTNRLAFIITHGKGYKIYIGIIVIGFIFMSLAHSGLNLPIIEKLHSL
                     EEVIAVIGILFSIIYMWCFKKVFKNSNQKEEENKKISLREMLIHSVGEISFVITWIFI
                     AYLIYDLIILILGGDEYLVKLVLSTGVISVFIGAGLGLIPGCGIQIVLMSFYLKGTIP
                     LGAVIANSISQDGDALFPLLAMDKKSSLWAMIITTIPAILVGMIVYAFLG"
     gene            16359..18056
                     /gene="ade"
                     /locus_tag="KOU88_002747"
     CDS             16359..18056
                     /gene="ade"
                     /locus_tag="KOU88_002747"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBK3212615.1"
                     /translation="MGNLKRQCDVSSGREKADIVLKNGTIINVFTEELITGDVAIVGD
                     TIVGIGDYKGNVEIDCSNKYISPGFIDAHMHIESTMVMPIELSKKLLKSGTTTIIADP
                     HELVNVKGASAIDFLLESTKDIPLNVYIMVPSSVPATSFETNGVGKFSAKDMESYVNN
                     PRILGLGEVMCFNDVINSENEILDKLELFKNKVVDGHAPNINGKSLQTYVCAGIENDH
                     ECITFDEVYEKLRAGLKILIREGSAAKNLKSIVSGMLKHNLPIEEFMFCTDDKHLDDI
                     EKQGHIRWNIKCAIDLGMEPVRAIKVATYNSAKAYGLRKIGAIGAGYKADIVVLNDLD
                     KMEVDSVYKDGNLVNEEMFSNYNYEIKDKELLNTVKFKYINKEKIQLKVSEKNYVMEI
                     VPYQILTNKLYESLPCADGYFVPNKEYSKLCVVERHRMTGNVAIAPLKGFGIKNGAIA
                     TTVAHDSHNIIVAGDNDDDILVAINYLKEIQGGYVIVSNGKVLAHLSLQVAGLISTFT
                     AEEVQEITDNMLEIARKMGVPEYVDPFITLSFMALPVVPQIRLTDLGLFDVEEFKFI"
     gene            18408..18872
                     /gene="bcp"
                     /locus_tag="KOU88_002748"
     CDS             18408..18872
                     /gene="bcp"
                     /locus_tag="KOU88_002748"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002586316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBK3212616.1"
                     /translation="MLSIGTKAPEFTLEDKDGNKVSMSDFKGKKVVVYFYPKDNTPGC
                     TRQACAFRNAYDGFKKEDIQVIGISKDSIKSHQKFAEKHELPFILLSDPDLVAIKAFD
                     VWKEKKMYGKTALGVVRATYIIDENGIIEKVFEKAKPDTNAQEILEYLEKQE"
     gene            18882..19625
                     /gene="yaaA"
                     /locus_tag="KOU88_002749"
     CDS             18882..19625
                     /gene="yaaA"
                     /locus_tag="KOU88_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBK3212617.1"
                     /translation="MIIMLSPAKNMKNIEVFDRDLSLPCFIDNTKEIVENIKTFAIED
                     FKNKMKINEKLAVLNKNRFESIKFDRLGNPAILTYDGIQYKNIEAENFTRKDEEFANS
                     CIRIISGLYGVVKPYDSIYEYRLEMQTKLRVGEFKNLYEYWGNRIYKELIKEKTAIVN
                     LSSNEYSKSIEKFIKDSDTYITCTFKVNKNGILKVESTQAKKARGMMTKYIVKNRIRD
                     IEELKKFNLEGYKYKENLSNNSEYIFVKE"
     gene            19753..22410
                     /locus_tag="KOU88_002750"
     CDS             19753..22410
                     /locus_tag="KOU88_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK3212618.1"
                     /translation="MENHKQMPWHSRATHEILESLDSSEEGLTDTEAEKRLKENGLNE
                     LRKKPPRTTLQMLWSQITDAMVMILIGAAILSLIFGEFTEAFVILIIVTVNAVIGIVQ
                     EKKAESSLEALKNMNSPTARVMRDGEENVIPASNLVAGDIVFLEDGAMVPADLRLIET
                     SSLKIQEASLTGESVPSEKDADTILPKECVLGDRSNMAYTSSIVTYGRGVGVVVATGM
                     DTEVGNIAHLLDSQDDFDTPIKRKLNTVGKTLSVIGIIVCVVIFAIGAFYQRPLLPMF
                     MIAISLAISIIPEGLPATATIVMALGVQRMAKRNALIRKLPAVETLGGATVICCDKTG
                     TLTLNKMTVTHIAVNGDFESGKVTSIDTASEKHPLVYKEIVYAGALCNDACINPDKTD
                     EILGDPTEGALIFMAKKFGIDQEALEEEYPRVFEQPFDSDRKCMTTVHNIDEKIIAYT
                     KGAVDEILDLCTKILTSKGERNITEVDKKNIHELCLNMSKDALRVLGFAKREISSIPK
                     EDSENIEYDLTFIGMVGMIDPPRTEVIDAVSTCKEAGIRTIMITGDHKVTATTIAHEL
                     GIWSEENTVISGDELDNLSDDELDEAVKNTTVFARVSPFDKLRIIQSLKRIGEVPAMT
                     GDGVNDSPALKSADIGIAMGISGTDVAKDSSDMILMDDSFTTIAYAIKEGRRVYRNIQ
                     KVIQFLLVGNIAEILTLFVAILLNWDTPLLAVHILWVNLATATLPALALGVDPPSRNI
                     MKHQPVKSTTLFEKNLIQRVVTQGIFVAIMTILAYKIGLNIENHSVGQTMAFCVLAFS
                     QMLRAFSQRSNTDSMFNRNNGKNPFLLISFLTSAFLIAVILFVPVFRNAFNLTVLNNL
                     EWLITIVLAIMSVIQVEVGKIIKRKKLKK"
     regulatory      22464..22566
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            22676..23941
                     /locus_tag="KOU88_002751"
     CDS             22676..23941
                     /locus_tag="KOU88_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HBK3212619.1"
                     /translation="MYNKETICVQGNYKPGNGEPRVLPLYQSTTFKYSSIDQLAELFD
                     LKVDGHIYSRISNPTIQAFEEKISLLEGGVSSVAVSSGQSANMLAVLNICKSGDSILC
                     SSKVYGGTFNLLGPSLKKFGIDLISFDLDSSEDEIVELAKENTKVVFAETLANPTLEV
                     IDFEKIANVAKRINVPFIVDNSLASPVLCNPLKYGANIVTHSTTKYLDGHASSVGGII
                     VDGGNFNWDNGKFPELVEPDPTYHGISYTQKFGNAAYATKARVQLLRDYGNCLSPFNA
                     YLTNLNVETLHLRMERHSENALKIARFLEKHENVDWINYPGLEDNKYYENAKKYLSRG
                     CSGVLSFGVRGGLENAKKFVEKLQIASLVTHVSDVRTCVIHPASTTHRQLTEEQLIAS
                     GVLPSLIRLSVGIENVEDLIADLNQALNF"
     gene            23971..24861
                     /gene="metA"
                     /locus_tag="KOU88_002752"
     CDS             23971..24861
                     /gene="metA"
                     /locus_tag="KOU88_002752"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBK3212620.1"
                     /translation="MALILPKGLPVINKLLDEGIDVIYKEDFKKELKYEENIDTKIAI
                     LNLMPIKIDTELDLLRRIDKTGFNVSVEFIKISTRESKRSCNEYVKEFYKTFDEAKGE
                     YFDGFIITGAPVEQMEFEEVDYWNELEEIMDYSKRKTKSTLYICWAAQASLYKYYNVK
                     KLPLSQKCFGVFKHKVDKDSKIVDGFENEFFAPHSRHTTVNIEALKENKELSIVSHSK
                     EAGPYIITNSRDVFVMGHSEYDKYTLDKEYKRDINKGDKISIPQNYYINDDPSEEPTV
                     KWKKHSELLFRNWIKNYLIQ"
     gene            25352..25795
                     /locus_tag="KOU88_002753"
     CDS             25352..25795
                     /locus_tag="KOU88_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3212621.1"
                     /translation="MDEMSFKKELLELTRDINMKFTTLLSDFYQPLGITAVQALILSE
                     LCEHGEKKISDLGKNLNMTNSNVSVICQRLEKNGFLNRIRDIEDQRIVKVKVTNKSLD
                     IQEHISSSIFDSYFENMTSEKLQDMEDIIEGLEKLNKLLTYIDCK"
     gene            25826..27643
                     /gene="ftsH"
                     /locus_tag="KOU88_002754"
     CDS             25826..27643
                     /gene="ftsH"
                     /locus_tag="KOU88_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBK3212622.1"
                     /translation="MDEHKPQKRSALYYYTVIIIVVMFLNALIFPSLMDKKMVEIDYG
                     KFLTMLDTGKVKSVEIENNRIAINPSSSKDKNIYITGRMDDPELVDRLKNAKVEFTKV
                     IPKENSPLLSILLTWIIPIGILMLFGNLMMKSMQKRMGGNAMQFGKSNAKMYVSAQSG
                     KRFNDVAGQDEAKEALTEIVDFLHNPEKYKKIGAQMPKGALLVGPPGTGKTLLAKAVA
                     GEANVPFFSISGSEFVEMFVGMGASRIRDLFKQAKEKAPCIVFIDEIDTIGKKRDNGS
                     GLGGNDEREQTLNQLLSEMDGFDGGIGVVILAATNRPDSLDKALLRPGRFDRRIPVEL
                     PDLGGREAILKVHAQNVNVSSDIDYNAIARSTSGASGAELANIVNEAALLAVKSGRDI
                     VEQQDFDESVETVIAGYQRKGAVISDKEKKIIAYHEIGHALVAAMQKHSAPVHKITII
                     PRTSGALGYTMQVAEDESVLMSKEEAIDKITTFTGGRAAEEVIFNTCTSGASNDIEQA
                     TKIARAMVTRLGMSEEFDMVALETVSNQYLGGDTSLACSSDTAAKIDEEVFKIVKACH
                     KNAIEILENNIDKLHELANYLLEKETITGDEFMEILNLN"
     gene            27821..30523
                     /locus_tag="KOU88_002755"
     CDS             27821..30523
                     /locus_tag="KOU88_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HBK3212623.1"
                     /translation="MDRPNPDILLEKIKNEEEKLSRGQLKIFFGYAAGVGKTYSMLES
                     AQNLKKVGVDVVVGYIEPHTRPETLALLDGLEILPVKEIEYKSIKLKEFDLDAALARK
                     PEVILVDEFAHSNVAGLRHTKRWQDIEELLLAGINVYTTVNVQHLESLNDIVEIITNV
                     SVKETIPDKFLDTNTQLELIDVEPDVLLERFNEGKIYKKEQATRAKNNFFIKDNLVAL
                     REIALRKTAERVNKEVQMTRLSKGDVTVIPTSDTLLACISPSPSSAKVIRTASRISDS
                     TFAKWIALYVETPNTARLPFDEQKQLQNNLKLAKKLGGEIIVLHGENIIEQILRIAKL
                     RNVTKIVIGRNHSSNKRFSKRFKKDIVDKLIDEVDYIDIHIIPYKFASDVKYKPKKDK
                     SSIKSKFKISKVDFIKLIFITLMISILAYAVQSMGFIRENILLIYMLGVVLVSMWTKG
                     YSTGIISSVFNIVLLNYFFTAPLYTLSIADSNYIVTLVVFSIVGIITSTLTSKIQHEA
                     ETAAKREENTKMIYQIIKGFLRLSNKDDIVNKGIELLSLSLSRDVICYLNVDKHNKSK
                     LYKKNTNNKDKNDLDSEDEKAVASWVLSNSTVAGNDTDTLPGSKGYYIPIVGMNLTLG
                     VVGISCIDSKLDTEDISLIETIIAQMAIALDREILSEAKENTNLEIERERLRSNLLRA
                     VSHDLRTPLAGISGAVSTIIKNKGTIGQDIIDELLSGVYEDTQWLIRLVENLLSMTKI
                     DEGKLEVKKHSELVEEIISEALQKIKKRIENALIDINIPEQILFVPMDAKLIEQVLIN
                     LIDNSLKYSKEDCKIEINVYEKDDYVWFEVSDNGPGISKELKKHIFDRFFTGEEGAKD
                     SRKGVGLGLSICKSIIQAHKGEIMVENNKDKGSTFKFSLPKENE"
     gene            30557..31255
                     /locus_tag="KOU88_002756"
     CDS             30557..31255
                     /locus_tag="KOU88_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3212624.1"
                     /translation="MSKKLILLVEDDKTIRKFISTALLTQDYDVKEAITGKEGISIAV
                     SYSPDVVLLDLGLEDMDGIEVIKAIRQFSNIPIIVVSAREQDRDKVEVFDAGADDYLT
                     KPFSIVELLARVRVAFRHSQVEAQQKDDVKSTFEVDKLLIDFDKRKVIVDDVEVHLTP
                     IEYNILSLLAKHHGKVLTHNFIIKETWGSVIGNETKSLRVFMATLRRKIEKQPANPRY
                     IITEVGVGYRLNDE"
     gene            31612..32568
                     /locus_tag="KOU88_002757"
     CDS             31612..32568
                     /locus_tag="KOU88_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CorA family divalent cation transporter"
                     /protein_id="HBK3212625.1"
                     /translation="MYILNLNTRETIEDFRDKFYVAENSYLILSAPKNLKLLKETLDI
                     DEITFNDCLKFDEITKLDLFDNYDFLSLNTFELRDGEAVIEEVNMYLSDNFILVVVNE
                     EHFLFEFVKNIILKNSQLEKNPVINLFKINYLILREVIKNGFESLEKVEELILQIEDE
                     MMDNINKNHVSRISDVRGLTRIIVKNTRPLLYIGDRIVKENIRYLKYSNVKKYNLENF
                     QGIDFGIDKLYNFALSTRELADKLLDIYSSRVGEKTNNLITKLTLLTAISAPLTIITG
                     IYGMNFRYMPELNWIYGYPATLFFMLCIIFVGIIIFKIKKLL"
     gene            32745..32900
                     /locus_tag="KOU88_002758"
     CDS             32745..32900
                     /locus_tag="KOU88_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212626.1"
                     /translation="MKGILKELTAKLYSFFYFMFWGFYFSAGYFFYKNICTSFLVRPY
                     FSDFEHK"
     gene            33030..34043
                     /gene="aroF"
                     /locus_tag="KOU88_002759"
     CDS             33030..34043
                     /gene="aroF"
                     /locus_tag="KOU88_002759"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBK3212627.1"
                     /translation="MIVVLKMGADKNEVKKLIEAIGREGVEVNPIDGTELTVLGLVGD
                     TSKIDAKRIEANKVVEKVMHVVEPFKKANRKFHPEPSIINVNGMEIGSKKIAMIAGPC
                     SVETEDQIVSIAKDVKKSGAGFLRGGAFKPRTSPYAFQGLKYDGLDLLKKAKEKTGLP
                     IVTEIMSTQDIDIFEENVDVIQVGARNMQNFDLLKELGKTNKTILLKRGLSATIEEWL
                     MSAEYIMAGGNENVVLCERGIRTFETYTRNTLDLSAILAVKKLSHLPVIVDPSHAAGK
                     SWMVDSLSKAAIAVGADGLIIEVHNDPAHALCDGKQSIKPNEYDELISELKTIASAVG
                     REI"
     gene            34065..35129
                     /locus_tag="KOU88_002760"
     CDS             34065..35129
                     /locus_tag="KOU88_002760"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBK3212628.1"
                     /translation="MEEKLLVNLKENSYNIFIKKNILKNIGEEIKKIYFGNKIFIVTD
                     ENIAKLYLDKVKNNLSESGFEIKSLILKSGEETKSFNTLPKIYDSLLDFKLTRKDLII
                     TLGGGVIGDLGGFAAATFLRGISFIQIPTSLLAQVDSSVGGKVGVDLERGKNLVGSFY
                     QPKAVFIDPNVLLSLPEKFYRDGMAEVIKYGCIKDKTFFNKLLSLKNREEVMQHIEYI
                     IHKCCFIKKTVVEADEKDFGDRMLLNFGHTLGHAIEKYYNFTGYTHGEAVAIGMYKIT
                     LESEKIGITKKGTSELIKSILMNYNLPYEIELRDNKSIVDAISLDKKNLGDTLKIILL
                     KDIGESIIYNTTSKFFQEVR"
     gene            35129..36442
                     /gene="aroA"
                     /locus_tag="KOU88_002761"
     CDS             35129..36442
                     /gene="aroA"
                     /locus_tag="KOU88_002761"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBK3212629.1"
                     /translation="MGSLKIYPSKLSGDVKIPPSKSMAHRAVICSSLSNGKSRISNID
                     FSDDIIATIRAMTSLGAIIEKKEDILEISGIFSKEGILNRENQLNQPKLTIDCNESGS
                     TLRFLVPISLTFDGVKRFIGRGNLGKRPLDTYYEIFDRQNIKYSYKENQLDLIISGKL
                     KPDEFRVKGNISSQFITGLLFILPTLESDSKIIITTELESKGYLDLTLSTIKDFGVEI
                     INNNYKEFIIKGNQTYKARDYKVEGDYSQGAFYLSADAIGEDISILDLKEDSLQGDSE
                     VVEILSRMGMEILREGNKIKGITNGLNGTLIDASQCPDIIPVLSVVASLSIGRTTIIN
                     AGRLRIKECDRLHAINVELSKLGANIEEKEDSLIIEGVSKLNGGVEVWSHKDHRIAMT
                     LAIASCRCDKPIILKDFECVSKSYPHFFKDFKMLGGRIDEWNMGK"
     gene            36420..37499
                     /gene="aroC"
                     /locus_tag="KOU88_002762"
     CDS             36420..37499
                     /gene="aroC"
                     /locus_tag="KOU88_002762"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBK3212630.1"
                     /translation="MSGIWGNNLKVSIFGESHGNAIGINIDGLPSGMELDLDNIDKEM
                     KRRAPGKNSISTSRNESDIPEILSGYFNGRTTGTPLCAIIRNSDTRSKDYGELKNLMR
                     PGHADFTGNVRYSGFNDYRGGGHFSGRITAPLVFCGAICKQILSQKGIEIGAHIKKIK
                     NIEDMSFDYVNISKQQLSNLQTLELPLLDLSKEEAMKNTIIDAKNQGDSVGGIIECAV
                     VGINVGLGNPFFDSVESTLSHLLFSVPAVKGVEFGLGFELADMYGSQSNDEMYYEGNQ
                     VKSKTNNNGGIIGGITTGMPIIFKVAIKPTPSISRQQNTVNIKDKKDDILYIKGRHDP
                     CIVQRAIPVIEAVTAIGIFDLMKGR"
     gene            37502..38698
                     /gene="pheA"
                     /locus_tag="KOU88_002763"
     CDS             37502..38698
                     /gene="pheA"
                     /locus_tag="KOU88_002763"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBK3212631.1"
                     /translation="MEDLTRYRNEIDNIDKELIQLFEKRMNTVLEIARHKMKNNTTIL
                     QKDREEKVLSRALDNLDNKAYSQETVQFFNSIMEISRGLQKRLIDNDGEQKIEFSLDS
                     SNKKFDLSNVNRYKSLKDELNKKNILVGFPGKSGSFTKEALNKFFNKKISKKQFKEFE
                     DVFIALKNKEINYGIIPIENSSTGAISETYDLLRKYGFYIVGEECIKIDQNLIGIKDT
                     KLEDIKEIYSHPQGIGQCSEFLKQNSTWKLIPFNNTATSAELVRKLQDKTKAAIASKK
                     AASIYGLEIISPCINDIANNYTRFVVISNQIHIEEESNKMSVVFSVEHEAGKLYKVLG
                     YFAKNNINMTKIESRPMKNASWRYFFYIDFECSIYNAKVYDLLELIEHNTAYFKFMGV
                     YKNKTE"
     gene            38745..39554
                     /gene="aroE"
                     /locus_tag="KOU88_002764"
     CDS             38745..39554
                     /gene="aroE"
                     /locus_tag="KOU88_002764"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBK3212632.1"
                     /translation="MNFFGLVGEKLSHSVSPQIHKRVFEILNIESAYKNFEISKEDIS
                     KLDGAIKLLGIQGVNVTVPYKERIMKYLDFISPEAKRIGAVNTILLRENMLYGYNTDY
                     FGLDSMFKMANIDVQGKVAVILGTGGASKAALTYFIDSGIEKLYVSTRKKDDKKLLNS
                     KAILIDYEELKHIKGDIILNATPVGMYPNVGISPVSKSIIQNFDILIDLIYNPGETEF
                     LRIGNSMGKKTCDGLYMLVGQAIKSQEIWQDTKIDNSILDVIYNELKLEFL"
     gene            39566..40099
                     /locus_tag="KOU88_002765"
     CDS             39566..40099
                     /locus_tag="KOU88_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBK3212633.1"
                     /translation="MINKTKEKLILIGMPGSGKTTIGKLLAKEYNCSFCDMDDYIIQI
                     SQKSIAELFSEGEDIFRNYETQACRELSISDKTVISTGGGVIKKDVNMEILKETGIII
                     FIDRPIQKILEDININSRPLLKNGKDRLYNLYNERINLYKKFSDIEILNDKSLNNAVY
                     NITNAVSENFKFDFKEK"
     gene            40120..>40907
                     /locus_tag="KOU88_002766"
     CDS             40120..>40907
                     /locus_tag="KOU88_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBK3212634.1"
                     /translation="MNIVIVGLGVIGGSFAKALKKAGYENVFGVDVDLETLKKAEKAK
                     IIKKGCTTGKELFKKADLIILSIYPRLVVDFLNNNKNFFKKGTIITDTTGIKETLIND
                     VLQIIPDDIDFIFGHPMAGREKKGIDFASEQVFNGANYIITPTGRNNIKNLELVENLI
                     LEIGFKRVKKLTSQKHDEIIAFTSQLPHVMAVALINSDEEGRDTGKFIGDSYRDLTRI
                     ANMNEDLWSELFLGNRDNLLKVIENFESEVNLVKEAIFNNDKNK"
BASE COUNT        16468 a         4254 c         7093 g        13092 t
ORIGIN      
        1 ggcaggagta tctaaaagta ctgtatcaag atatctaaat aataaagata tcagtgattc
       61 tactaaagag aaaataaaga caataataga tgaatatgga tatgagccga atgcatttgc
      121 tcaaagtttg agagctaaaa aaacatactt tattggtatt ataacaccgt gtttagattc
      181 ttttgtaaaa tctaaaatta tgatggcaat agatgaagaa ctcaaagaat taaaatatac
      241 atcactaatt attaatacta atagaaaaat aaggtcagaa atagatagta tatcaaagtt
      301 agctagtcta aaagttgatg gaataatact aattggtacc gaaataacta aagaacataa
      361 gaatgaaatt gaaaagttag atataccgat agttgtagtt ggacaaaaag ttgatggtat
      421 caatagcata gtgaatgatg attatggagc aggatataaa atgggtcaat atattgctaa
      481 taaaggttac aaaaacattg tatatttagg tgttgatgaa agtgatatat cagttggttt
      541 aaatagaaaa aatggagtac ttaatgggtt aaaagataaa gggtatgatg caaaagtatt
      601 ttatactgac tttgaccaag aaacgtctat acaaagaagt ggagaaatgc tagaaagtga
      661 aaatccagat ataataatat gtgcaactga taatatagca atagcaacaa tgaaagaaat
      721 caataagaga ggtaaaagta taccacaaga tatatctgta gctggatttg ggggatatga
      781 tgtattgtct attataagcc ctaaacttac aacaataaag tttgaaaata aaaatgcagg
      841 taaagtagca gcaaatacga tagtaaattt aatacaagaa agaaaagaac cactattaaa
      901 ggagattaaa tttgaattaa tagaaggtga aagtacaata aataaaaatt aagatacaca
      961 ttacatatat tagtaatgtg tattttttta ctaaaaaaac tataattcta aaaattagga
     1021 aaactttttc gaaagaaata ttgcatctga aataaattta tgctaatctt taattaaacc
     1081 ggtttcgaaa ccggtttaat taaaccgata gaatagcaaa atgagtgcaa aaataactga
     1141 ttgtaacaaa gtatcaaagt aattattaga gtacatagga ataaacaaaa tataaaagat
     1201 gtagcacatt gtgtaataag actaagaatt gttttagata gcaataataa agcaaatata
     1261 aaattataaa agaaaaggaa taaaaatatg tacaaagagc ctaaatatag aaccatatta
     1321 gaatcgacaa aagaagaatt aaataaatta agaaatatat ctttaaatga taaatataaa
     1381 ccactatttc atatacatcc acaacatgga ctacttaatg acccaaatgg attatcatat
     1441 tataatggta agtaccatgt attttatcaa tggtatccat atgatgcaac tcatggaatg
     1501 aagcattggg cttatgtaag ttctgatgat tttgtaaact ggaatagaga agatgtagca
     1561 ttaataccaa tcgaaagtta tgaatctcat ggagcatatt caggtaatgc gatagaggta
     1621 gatggaaaat tgcatatgta ttatacaggg aatataaaat atagtgcaga agatagatat
     1681 gcatatcaaa acttagctat aatgaacaag gatggtaaaa taactaaata tgaaaataat
     1741 ccaatagtaa gtgaaatacc aaaaggatat acaggacatg taagagaccc aaaagtattt
     1801 aaaagaaagg ataaatactt tatgttactt ggagcacaaa caagtgataa aaaaggagtt
     1861 ataatagtat atgaatctaa aaactctata gattggaatt ttaaaggaga attaaatgta
     1921 aaaaacatag atgaagattt tggttacatg tgggaatgtc cagattatat taatatagat
     1981 gaaaaagata tattaatatt ttcaccacaa ggagtagaac ctaaaggatt tgattatcaa
     2041 aatatatata atgtagtata tgctattggt aatatggatt tagataattt aacatttgaa
     2101 atagatacaa tgaaagaact ggaaaaagga tttgatttct atgctccaca aacatttata
     2161 aaggactcac aaataatact atttgcatgg gctggaatgg gagaagtttt ataccctaca
     2221 gataaaaaca aatgggcaca ttgtctaact gttccaagaa aattaaatat aaaaaataat
     2281 aagctattgc aaatgcctgt agatgaatta attaaattaa gatatgatga aacaagtggg
     2341 caaaatacta taaagaataa tatcaatatt atagaaaata atgaaaatgt atatgagctt
     2401 aatattaata taaaaaatat tgacagcaat aaatttgggc tggaattatt ttcatcacaa
     2461 gatgaaggtg taaaattaga atttaacaaa ttaggaaaca ttgtaacttt agacagaagc
     2521 aactttaaaa aagttttcgg tgttgaatat ggaacaaata gaaaagaata tataaatatt
     2581 gatgaaaata ctaatatcaa agtactagcg gatagaagta ttttagaaat ttttataaat
     2641 gaaggagaag tagtatttac tagtagaata tttgctaaag aaaattctaa tcaaataagg
     2701 gtttatagtg ataaaatagt agagtatgag tatactaaat ttaaattaaa gcaaggtatt
     2761 gaattataaa aacacattat aaggggtaga aaagatgaaa aaagtaatta gcataggaga
     2821 agctttaata gactttatac cgaatcaaaa tggtggtaaa ttaaaaaatg tatcagaatt
     2881 tagaagagta gcaggaggag ctccagcaaa tgttagtgct gttgtagcaa agcttggagg
     2941 aaaatcgagt tttatatcta agttaggaaa agatgcattt ggtgattata taatagatgt
     3001 attaaatgaa gtaaatgtaa atactgatta tgtattgaga acaagtaaag caaatacagg
     3061 acttgctttt gtatcattaa aagaagatgg taatcgtgat ttctcatttt atagaaatcc
     3121 aagtgcagat atgcttttag aagctgatga agttaaaaaa gagtggttta ataattgtca
     3181 tatcctacat ttttgttcag tagatttaat agatagtcca atgaaattag cacataaaaa
     3241 agcaatagaa tacgcacttg aaagtaatag tataataagc tttgacccta atataagatt
     3301 acctttatgg gatagtgagc aatcttgtaa aaaggcaata tcagaatttt taccttttgc
     3361 tcatattgtt aagatatctg atgaagaatt agaatttata acaggagaaa atgatataga
     3421 aaaatcatta cataaactct ttgtggggaa tgttgaacta gtattatata caaaaggaaa
     3481 agatggagta gatgcataca ctaaaaaagt aaaaggtatg tgtaaagggg ttaaagtaaa
     3541 tgcaatagat acaaccggag caggagattc ttatataggt tcatttttat acaccttatt
     3601 gtataaacaa ataacattga atgatataaa agaaatgaaa caagaaacgt taaatgagta
     3661 tttagaattt tctaattatt atgcagctcg tagtacaact attaaaggtg cgataagttc
     3721 atatgcaaca aaggaagaaa taactgaatt tataaaaaat ttatagtagg aatgagtaat
     3781 aggttttgaa ggaagtaaca tgtaaagagt ttttaaggat gtttactatg aaaataatta
     3841 acatataaaa agcaataaag aggctgtctc aaaatagaga taagcctctt tatcattgtt
     3901 gaaatgataa aaaatatttt aattattgtt actttttaga agaatatata tcttatttta
     3961 aataagcaaa ttatgtaaga tttatttata ttatcaatac tttacttgga gtattatgtc
     4021 tttagcagtt atctacttca attgaattat ctaaaatata ataaatttgt tttgcaaatt
     4081 gacgagaatg ttcttctttt tctttattca taaaattagg tttacctaaa tcacgttcaa
     4141 caagcattcc tatatatttt aactgtgaat gcttacagta gcgcttcata ccattttccc
     4201 aaatatcagc acccttttca ggtctatatc cacatgttgt aataagtgct actggttttc
     4261 ctgcccatag agcggggcct ttctcattac catagtattt attcattcca tacaccaatc
     4321 tgtcaagtag tgctttcatt ggagaagtgc agtaccaaga ataaattgga gtagcaaaaa
     4381 caattaaatc acacataaga attttcttga aaattttctg aacatcatct ttacaataac
     4441 atccaaaatc aaataagtta tcctgacatt ttttacaagc aatacatggc tctattttac
     4501 aatcatataa ccatattact tcaatatttg aattataatt ttctaattcc tcaataaaag
     4561 gttttaaaat agcagcagta ttaccttttt tcttaggact tcccataaga atgcatactt
     4621 ccatattgat acctccacag tattttaaaa tagtttttag tgcttaatat agttttagga
     4681 tactatgaga atacgttaac aacaatacac tttgtatatt tgtaataaaa ttgaaacaaa
     4741 ttgttttatc aataaaagtt ggaatgtatc tataattaaa aatattttag gtatgttttt
     4801 acatatatgt gtgtagttaa ctatggtaat ttattgtaaa attatcttat aggattataa
     4861 ttgcttaatt tatgattata tttaaaatct tggaggtaaa aaatatgtac tcaaatgaag
     4921 actataaatt tatagaagaa aatgcaccat gttatatata tgatgagact aatataattg
     4981 aaaaatgtaa ggaattgaaa aataatattt taggttttga ttttttatat tctataaaaa
     5041 caaatccata taacaaaatt gtaaaaagca ttgcagagca aggttttgga gcagatgctt
     5101 cttcaactaa tgaagttatg atttcatcag aatgtggagt ttctaaagat gatatttatt
     5161 attcatcacc aggcaaaaca gagattgata tagaaactgt tttagataaa tgcataatta
     5221 ttgcagatag tattacagaa atagaactta taaataagat atctaaaaag cataatcaga
     5281 aagttaaaat aggaataaga ataaatcctg attttactat ggatgatgat agtgctaaat
     5341 caagcaaatt tggtatagat atagaagata tgagcagtgt ttttaagatg ttaagtatgt
     5401 gtgattatgt atctgtagtt ggtattcata tacatattaa atctcaggta ttggattttg
     5461 aaaagttagg acattattat gaaaaatgtt tttttatagc tttaaattta aataaaagta
     5521 agtatattaa tattgaattt ataaattttg gtagtggact tggagtagct tatgataatc
     5581 ttagagaaaa tccacttaat cttaaagagc tttcaaaatt aactcaaaag attgctttta
     5641 ctaattcaaa cacactaaaa tcaagacttc ttattgaatc aggacgtttc atagtttgta
     5701 aatcaggtaa ttattatgtt aaaattgtag atattaaagt atcaagaggg aaaaaatatc
     5761 ttattgtaaa aaatggactt aatggattta tgagacctat tatttctaat ttaattgaaa
     5821 atattacttg tggagtagaa ttagaaggtc aagagccatt atatacatca aatcatgcct
     5881 tttctctttc agtattaaat aatttaaaag aagaagagta tgtaaatgtt gttgggaatc
     5941 tctgtacatc attagatgta attgcaaata atgttaaatt gaaaaaagca aacataggag
     6001 atttgatttc aattagtaat gctggaagtt actcctattc tttatcaccg ctattatttt
     6061 caagttatga atttcctaaa caatattata aaagaaaaga tggatatatt gagtaaacaa
     6121 tagcataaat taataaactt agtattattg aaaaaattta aaatgcaggg ggtgtaattc
     6181 tatatggaat tgtggaaaag aaatttattt gtatgttgga taggtatgtt ttttagttct
     6241 atagggatga gccaaatagc acctatactt ccattatata ttaaacagtt gggggtaact
     6301 gatgttagtt taatacaaca gtattcaggt ataatttttg gatgtacctt tgtagtagca
     6361 gcattctttt cgccaatttg agggaaagct gctgataaat atggaagaaa atcaatgctt
     6421 ttacgtgcaa gtattgggat gggaatagtt atatttacca tggcgtttgt tcaaaatgtc
     6481 tatcagttat taggattaag aatacttcaa ggagttttta cgggttatgc tactgcatgt
     6541 actactctta ttgcaacaca gacagataaa aatcattcag gatgggcttt gggtactctt
     6601 gcaactgcat caactactgg ctcattaatt ggtccaacag taggaggata tatagaatca
     6661 atcttaggtc ttaaaagtac atttattata acaggaggat tgttgtttgt atcatttatc
     6721 atctctattt tatttgtagt agataatttt aaacctaaag aaataaaaga atcaatttct
     6781 atacctaaag aacaattaaa tatattgcca aataaatttt taattgcatc tatttttgta
     6841 accacattca ttactcaact agctttatac tctatagaac caattgtaac catatatata
     6901 tcacaactta caaattttgc atcaaatgta gctttaatag ctggattgac attttctgca
     6961 tcaggattag caaatttatt agcagctcaa aaacttggaa aaatgtcaga taaaataggt
     7021 cctcaaaaag tattgttaat ttcactttta tgggctggga ttatatttat accacaagct
     7081 tttgtaaaaa ctgcatggca actgatgttg ttgagatttt tattagggtt gtcagttgca
     7141 gggcttaatc cttctgttaa cagcttgctt aaaaaaattg caccagaaga atatgtggga
     7201 aaaatatttg gatataatgc atctgcccag tatataggct gttcatcagg agcattttta
     7261 gggggacaaa tatcagcaca tttaggtatt agaacagtat ttttttcaac aagtttattg
     7321 ttgtttatga atgcactttg gatgtataaa tttactggat tgtttattaa agataagact
     7381 aaataatcat actatttaca tttctaattt tatgatgtaa aataaatatt ttttatgtaa
     7441 tttatcatag aattatataa aaaataaccc tatggtaaaa attggaaaat attattatcg
     7501 acaaaatctt tgacttaaaa actatattgc gatagtatta atttaataaa agtttgagag
     7561 gggcgtaagg ttatgacaat ttcaaaaata ccacaagcag aattaaaagt tatgaagttt
     7621 atttgggaaa aaaatgatac agtaacatca aaagaaacta ttgaagctat ggaacgaaaa
     7681 tatggttgga aacaaacaac tacattgaca cttttatcaa gacttgttaa aaaacatttt
     7741 ttaagtgcag aaaaaataga tagatacact cattatacaa tagttgttgg acataaggag
     7801 tatttaagtg ttgagacaaa agatttttta agcaatatac acgacaattc tttacagagt
     7861 ttaatttcag cactacatga tgatgaagtt gttgataaag atatgttgga tttatttgaa
     7921 agtcatttta aaaatttaga agaagagtaa ttatatcagg atagaactct aagaatttaa
     7981 ttaatctatg gctgaaaacc ataaatggta ttatttaatc agctactcac tattcataaa
     8041 gtaatattaa ataggttctc taattagtaa aatgcctaaa ataattggaa tagggagtat
     8101 caagttaaat gataccactt atttaaataa gaaatgattt ttaaaattta aaataatttt
     8161 ataacttgtc aatattcatt aatctaaagt attatttcta tttaaccata tcaaaatata
     8221 ttttactatt tttaattatt acaatataaa cctgtctttt gttattatag gtaaactaaa
     8281 agtaagaaat gatttttata tttttaaact ttattattgg taacttatct gtaaatattt
     8341 taaaatgtac tatagaaagt tgttaaaaat attaaataat tatattaaat ttaagtgtgt
     8401 tttttatgct ataattagta tgtatttttt atgatatatt ttataaaaaa tataatttaa
     8461 tcatttttga ggatattatt atgttagatg catttataac aattgtttct tctattatag
     8521 aaatatggtc atgtaaaaaa gtttttgatt atactagtca gtcaaagacc gacttaaaaa
     8581 aactaaatat gtattttctc ttttctgttt ttctcattat ttcttcttta tatataaata
     8641 taggagctaa tagtagaatc ttgatatgta tatttgtaat gttcgttttc tataagtcta
     8701 actataaggt taatatatat aaatgtctgg taatctcatt tttttattgg ttaatattaa
     8761 taggtataaa tggattaagt atgttattag tagcaacagt aagcaatttg gataatatga
     8821 atgttttact tagtggcagt ttatatagat atgaagcaat attcttggga aagataatgt
     8881 taggtatatt actttatgtt tataaggctt cttttaaaaa ttttaaaata agtaaaaaag
     8941 agatatacat atgtattcct atgatagcaa atttattgtc attttttgta ctttatgatt
     9001 atattattaa tcttgtaaaa atctctcctg aaagaagaac tgctttttta gtaatagttt
     9061 tactattaat attatctaac atttcaatct ttgtattaat acatataata cttaagatta
     9121 aaattaggaa aataagataa attttaatac gattcattta aattaaaagt taataattac
     9181 ttttttatgt ataattttac atgaatttct ataaaagtta ttttattaaa gatagatata
     9241 cttatatata cggatatgat taaaaaaagt ctttttaact ttaaaaatta atgttaaaaa
     9301 ataaacttat acactaatat taataataat tatttaaata tcttaagtaa atcagtctta
     9361 catatatttc cgatagatta tattgataaa aaacactaaa attaaattaa taaaagtact
     9421 tggagggatg gaaatgaaag aggaaaattt tattaatgtt gaatacgagg ataaacgttt
     9481 ttcaattaat agtaaagaag ttttgtacat agaaaagcaa gagtatgaag taaagattta
     9541 tactgaaagt gctaattatg aagttggaga aaatgctcct tgtataagaa aactattgaa
     9601 agaagaaaat tttttcaaat gcagtaatag ttatattgta aatctagaca agtgtgaatt
     9661 ttatctcagc aataattgta tttttgtgaa taataatttt ataagaattt taggttcaga
     9721 aagaaaaaag aaattaaaaa agaaattaga aaaattatat gattatgaag attaatattg
     9781 ggaggctgta ttttatacag cctctttatt tattgattgt attattaata aattttaaat
     9841 tatgataaaa tataaaacaa gtaacttatt tcagaataaa atacttttta aaagaaaggg
     9901 acaagatatg ggagattata ataaaatgat tgaattaaag aataacttag gtatcagtga
     9961 aagaaagtta aaatatcctt gtatctataa acattttaaa gggaaatatt atgctacaat
    10021 gggtcttagc aaggctattg atgatataga aaacatatgt gaaatatatg gtaaagaaaa
    10081 tttaatccaa aacagaaata aatataaatt agttattaga catactgaaa gagaagaaga
    10141 tatctatgtt tatagggatt tagatggaaa cttttatcat aaaaaagaag aagatactaa
    10201 tgatttagtt ttatacaaga ccttatatga tgatacagga atatttgcaa gacctttgga
    10261 tatgttttta gaaaaagtag atacagataa gtatgtcaat tcaattcaag aatacagatt
    10321 tgaagaagta tataaataat ataagagaaa tatgcttata aatttagaaa aattttttaa
    10381 cagtacaata atttgcagaa atacaaatga gatttattgt aaataatatg ttagattaga
    10441 ttataaaata gaaacaaagt aaagtattat atgatataat taagttttga gaagtgataa
    10501 tttatattta ataaaaaata ggcatatatt aggaggacat atgggaaata ctttttatat
    10561 agtaagacat ggacaaacgg attggaatat attgggaaaa acacaaggtc atggtaattc
    10621 tgaccttacg cctcaaggta tagaacaggc aaaagaactt tctgaagata ttggcaagta
    10681 ttcaattgat tatattttta gtagcgacct tgggagagca atgcaaacag ctcaaatttt
    10741 aggagataag ctcaatattg aagttcaaaa aactgaggca cttagagaaa tgggattcgg
    10801 agtttgggaa ggccttttaa taaaagaaat tcaaaaagat tattcagata tatatgcaac
    10861 atggagaaat gaaccacact tagtaaatat accagaaggc gaaactctta agattataaa
    10921 ggaaagagta gatgctttta taaaggaact aaatgaaaaa tatgataata aaaatataat
    10981 tcttgttaca cattcaatta cattgagggt tatgttgttg tcgtttttag aatcaggtat
    11041 ggaaaatata tatagaatta agcaagataa tactgcttta aatatagtag aatttaaaga
    11101 ttatggacct gttatagtaa aaatgaatga tacaagtcat ataaaaaatc atgtaaagat
    11161 aaataattct gcactggagt aggaatcaat tataaggaga aatttatgag taaagttata
    11221 gtagttggtg gaggagcttc tggaatgatg gcagctttgt cagcttcaaa aaacaataat
    11281 gaagtaatat tagttgagag aaatggagaa ttaggaagaa aacttagggc aactggtggc
    11341 ggtagatgca attttaccaa taatagagag atagaagatt tttttgataa agttgtcagt
    11401 aataaaaaat ttctctatag tagtttctat acatttacaa ataaagacct tatttcgtat
    11461 tttgaaagta gaaatttgga atataagatt gaagaagaaa atgaccacaa agtatacact
    11521 aaaaatgata aatctataga agtaatagaa gtattaaata aagatttact caatcacaat
    11581 gtaaagataa tgtataataa gaaagttata gatattataa ctgaagaaat tgctctaaaa
    11641 gatgattcta ataaggacaa gtcaaagtat ctaataaaag ggattatttt agataatgga
    11701 gataagatac taggagacaa ggttattata tcaactggag gagtgagtta ttcaaagacg
    11761 ggttcagatg gttcaatgta taagattctt aaaaagcatg gacatacatt aaacaaacta
    11821 tatcctgctt tagttccact tacaatagag gaaaaatgga ttaaagattt acaaggaata
    11881 tccatgaaga atgtggaaat atcttgtaag attaagaaaa ggaaaatatc aaaatctgga
    11941 gacatgctat ttgcccattt tgggataaca gggccttgtg ttcttataat gtcttcttat
    12001 attaacaaga ttattgaaaa ggaaaaggta gaattaaata tagatttctt accaaattta
    12061 agtactgatg aaatctctag tataatcaga gcatttccaa ataaaaatgt tctaaataat
    12121 cttaagcaaa tactacctca aaatttctta aaagagattt tttctctatt atctttagtt
    12181 gataaaaagg caagtgattt gtctaaggca gatgaaatta gaattattga gtatataaaa
    12241 aatatgaagc taacttgtaa tgggactaca ggtataaaca ctggtatggt tacttctggt
    12301 ggtatttcag ttaaagaaat taattcttct actatggaat ctaaattagt taagaactta
    12361 ttttttacag gtgaagtaat tgatatagat gcagaaactg gtggatataa tttacaaata
    12421 gcattttcaa ctggatatct tgcgggtata agtgtataaa tataattttt taataattaa
    12481 atatgaataa atagaggtgt atatatgggt aatttagtta tagctgtaga tggtccagca
    12541 ggagctggaa aaagtacaat agccaagata gtagcaaaaa agctaaatat aaattatata
    12601 gatacaggtg ctatgtacag agcagttact tataagtgtt taaaaagtgg tattgatgtc
    12661 aataatgaaa aagaagttat tcaaatagct gaaaattcgg atatagattt taaagataac
    12721 aatatatatt tggacaaaga agttataaat gaagaaataa gaacaataga agtaagcaat
    12781 aatgtttcta atgtagcaaa aataaaagaa gtaagacagt tgatggttga agttcaacga
    12841 aaaataagaa tgaaaagttc agtaatacta gatggtagag atataggttc atatgttttc
    12901 ccagatgcag attacaaatt ctttttagta gctactccag aagaaagagg aaatagacgc
    12961 tataaagaac tttgtaataa aggatataat actactttag aagaagtaat tgaggatata
    13021 ataagacgag atgaaattga ttcaaataga gaatttgcac cattggtaaa agctaatgat
    13081 gcactagaaa tagatactac aggaaaaact atagaagaag ttgtagaaga agttgtatct
    13141 aaaataaatc tttagttttt tatgcatcat aatgaaaata aatgtagtgt tgaagggaga
    13201 taaacgtgaa tttttataga tttgtaataa atatttttaa gggtttttct aaaatatttt
    13261 ttaaatatga agttataggt gcagaaaata ttccagatag aggaaatata gtaatagcat
    13321 caaatcataa atcgaatctt gaccctatat tcttggctgc tgccatagaa aatagagaaa
    13381 tagctgcaat tgcaaagaaa gaattgttta aagtaaaacc attgggattt atattaaaaa
    13441 aattgcatgt tatgcctata aatagagaaa aaccagatgt atctacaata aaaactattt
    13501 taaggtcagt tagagatggt tatgtattag gaatatttcc agagggtact agaataaaag
    13561 gagattcttt tggtaaggct aaggcaggtc tttctgtatt tacaataaaa agtaaatcta
    13621 aagttgttcc agtatcaata atatctaaat ataaactttt tagtaaagta attgtatata
    13681 ttggagaacc aatatcattt gaagaacatt ttaaggaaaa attgagtaat gatgaccatg
    13741 aaaggatatc acaagagatt ttagaagtga taaaacaaaa ttactttaaa tattcaaaat
    13801 aagggggtaa agttatgaac ataaaaatag caaaaaatgc tggcttttgt tttggagtaa
    13861 aaagagcaat gaaaatggca tgggatgaag ttgaaaaaaa tgattctggc atatatgctt
    13921 taggtcctct tattcataac aagcaagcag tagcaaaata tgaagaaaaa ggtcttaaga
    13981 ctgtgaatga aattgataca ataccaaatc atgaaaatat gataataagg tctcatggag
    14041 ttcctgaaaa tatatataag gaagccaaag ataaaaaatt aaaaattgtg gatactacat
    14101 gtccatttgt aaagaaaata catacagtag taagtgagta tcataataaa ggctatgaaa
    14161 taatagttat tggagatatg aagcatccag aagttatagg tataaatgga tggtgtgaaa
    14221 attcagctat aataataaag accttagaac aaatggaaaa tatggaattt gataactcca
    14281 aaaaatattg tcttgttgca cagactacaa taaatccaga gttgtatata agtatagtta
    14341 ataaactatc agataaatta gaagaaatag tatttaatga tacaatttgt tcagctacaa
    14401 aaacaagaca agaatcagct aaagagttag ctaaagaagt tgattgtatg atagttatag
    14461 gaggtaaaca cagttcaaat actcaaaagt tagtaaaggt ttgtgaagac ttagtaccaa
    14521 cttttgcaat agagactaaa gatgaattgg atgtaaatac gcttaaaaaa tataaaaatt
    14581 tgggtattac agcaggggca tctacaccta attggataat agaagaagtt gtaacattcc
    14641 ttgaaaattt ataatttgat aggtaataaa aataggtgga cattgttata atttatcata
    14701 atatccacct ttgatttcat attacatgtg gtaaatagat aacctaatat caaaaagtgt
    14761 gtatcttaag atgaaaaact aagagtataa gatgcgcact ttttaatatt agaaattcaa
    14821 aagaaatatt gatattgatt atcaatagaa aacagaatat aatataattg ttgcaaaatt
    14881 agtctaggag gtaaattaat ggaaatgttg atatccgctt ctgaagaggc gtttttacat
    14941 gtaggttcta tgattggatt ttttattttg ttatttggat atattaatta taaaactagt
    15001 ggaaatttta ctaatatcat atcaaaaaac agaaaatttc aaccattaat aggtgcttta
    15061 attggagcta taccaggttg tggcggaagt ttggcaataa tgccattgta tataaatgga
    15121 aaattaagct ttggagcaat aattgcaagt ttaatagcta gtatgggaga tgcagcattt
    15181 gtacttattt catcaaatat taaaatgtat ttttttgtca ctatagttag tacaattaca
    15241 ggaataataa ctggacaatt agtggattac tttaaactag aagaaaaatt agggttaaaa
    15301 aaccgtagaa aatcagataa atatgatata agtaaaaata actctaaaga aaataaagaa
    15361 caacataatc atgatgaaat aattttagac actctagcta aatctcatgg aaatacaaat
    15421 agacttgcgt tcataataac acatggaaag ggatataaaa tttatatagg aattatagta
    15481 atcggtttta tatttatgtc acttgctcac tctggactta atcttcctat aattgagaag
    15541 ttacattcat tggaagaagt aatagcagtg attggaatat tattttcaat aatttatatg
    15601 tggtgtttta aaaaggtatt taaaaattct aatcaaaaag aggaagaaaa taaaaagatt
    15661 tctttgcgag aaatgcttat ccattctgtt ggagaaatat catttgtaat tacatggatt
    15721 tttattgcat atcttattta cgatttgata atattaattt taggtggaga tgaatactta
    15781 gttaaactag tattatcaac aggtgtaata agtgtattta taggtgcagg tcttggactt
    15841 attccaggtt gtgggataca aattgtgctt atgtcatttt atttgaaggg aactatacca
    15901 cttggtgcag tgatagccaa ctctatttct caagatggag atgcactttt cccactttta
    15961 gcaatggata aaaaatcttc tttatgggct atgattatta ctactatacc agcaatactt
    16021 gtaggtatga tagtttatgc atttttaggt taaatataat tacgaataaa gaagtattaa
    16081 aaaaataata aagcacataa atttatttat aagaatagtg aagattaaat ataaaaataa
    16141 aaaattcaat atgaattaaa ttattgctta aatattaatg agaacatggg agataatatt
    16201 attcctcatg ttctctctat ttaattaaag gaattatgga acaaatttca agtgatactt
    16261 tctatcaaaa ctcatatata atatatatta ataaattaaa ctataatacg taatacagtc
    16321 agtatattga tataaaaaac ttaggagggg ttataaaaat gggtaattta aaaagacaat
    16381 gtgatgtttc aagtggaaga gaaaaagctg acattgtact aaaaaatggg acaatcataa
    16441 atgtatttac agaagagtta ataacaggag atgtagcaat agtaggagac actatcgttg
    16501 gtattggcga ttacaagggc aatgtagaaa ttgattgtag caacaaatat atatcacctg
    16561 gctttattga tgcacatatg catattgaat ctacaatggt aatgccaatt gaattatcga
    16621 aaaaattatt aaaatcaggt acgacaacta tcatagccga cccacatgag ttggtcaatg
    16681 taaaaggagc tagtgcaata gattttttat tagaatcgac aaaagatata ccacttaatg
    16741 tatatattat ggtgccttca tccgtacctg caacaagttt tgaaactaat ggagttggta
    16801 aatttagtgc aaaagacatg gagagttatg taaataatcc tagaatttta ggtttaggag
    16861 aggtaatgtg ttttaatgat gttataaatt ctgaaaatga aatcttggat aaactagagc
    16921 tttttaaaaa taaagttgta gatggacatg cacctaatat aaatggtaaa tcacttcaga
    16981 catatgtatg tgcaggaata gaaaatgacc atgaatgtat aacttttgat gaagtatatg
    17041 aaaaattgag agcaggatta aaaattttaa taagagaagg aagcgcagca aaaaatttaa
    17101 agtctatagt aagtggtatg ctaaagcata acttgccaat tgaagaattt atgttttgca
    17161 cagatgataa gcacttagat gatatagaaa aacaaggtca cataagatgg aatataaaat
    17221 gtgcgattga tttaggtatg gaacctgtta gggctataaa agttgcaact tataattctg
    17281 caaaagcata tgggttaagg aaaattggag caataggtgc gggttataag gcagatattg
    17341 ttgtattgaa tgatttagac aaaatggaag tggatagtgt atataaagat ggtaatttgg
    17401 taaacgaaga gatgttttct aattacaatt atgagattaa agataaagaa ttgcttaata
    17461 cagtcaagtt taaatatatt aataaagaaa aaatacagtt aaaagtaagt gaaaaaaatt
    17521 atgtaatgga gattgtacct tatcaaattt tgacaaataa gttatatgaa tctttaccat
    17581 gtgcagatgg atattttgtt ccaaataaag agtattcaaa actttgtgtt gttgagagac
    17641 atagaatgac tggaaatgta gcaattgctc cactaaaagg atttggcata aaaaatggag
    17701 caattgctac tactgtggcc catgattctc ataatattat agttgcaggg gataatgatg
    17761 atgatattct agtagctata aattacttaa aggaaataca aggtggttat gtaattgtat
    17821 caaatggaaa agttcttgca cacctaagtc ttcaagtagc tggattaatt agtactttta
    17881 cagctgaaga agtacaagaa attactgata atatgttgga gatagcaaga aaaatgggag
    17941 ttccagagta tgtagaccct tttattacac tttcttttat ggcacttcca gttgttccac
    18001 aaataagact tacagattta ggtctatttg atgttgagga atttaaattt atatagataa
    18061 tataaaagta ataataaatg aggctttctc aaaataggga taagtctctt tttattgttg
    18121 aaatgatgga aatatatttg atttcataca aaaaagagca tctcatgaac taaaaatttt
    18181 atttttagat atccttattt taattaatct atcatttaac cttgttttaa gcatagatat
    18241 cttaataaaa ctattttcag tctattttaa catataaata catgaaaatt atatatttat
    18301 gaaactttat acataaaaaa taaaatattt tatttatata tagatttata gggtaataat
    18361 ataagcatag tataaaatta ttaataaaaa caaaaggaga gatatttatg ttgagtatag
    18421 gaacaaaagc accagaattt acactagaag ataaagatgg aaataaggta agtatgtcag
    18481 attttaaagg caaaaaagta gtagtatatt tttatcctaa agataataca ccaggatgta
    18541 cacgtcaagc ttgtgctttt agaaatgcat atgatggttt taaaaaggaa gatatacaag
    18601 ttattgggat aagtaaagat agtataaaat cacatcaaaa atttgcagaa aagcatgaac
    18661 ttccttttat tttactttct gaccctgact tagttgctat aaaagctttt gatgtatgga
    18721 aagagaaaaa aatgtatgga aaaactgcat tgggagttgt acgtgcgaca tatattatag
    18781 atgaaaatgg aattattgaa aaagtctttg aaaaagcaaa accagacaca aatgcacaag
    18841 agattcttga atatttggaa aaacaggagt aataagaatt tatgattata atgttatcac
    18901 cagctaaaaa tatgaagaat atagaagtat ttgatagaga tttgagtttg ccttgtttta
    18961 tagataacac aaaagaaata gtggaaaata taaagacatt tgctatagaa gattttaaaa
    19021 ataaaatgaa aattaatgaa aaattagctg tattaaataa aaatagattt gaaagcatta
    19081 aatttgatag attaggaaac cctgcaatct taacttatga tggaatacaa tataaaaata
    19141 tagaagcaga aaattttaca aggaaagatg aagagtttgc aaatagctgt attcgaatca
    19201 taagtggatt gtatggtgtt gtaaaaccat atgatagtat atatgaatat agattagaaa
    19261 tgcagacaaa attacgagta ggtgagttta agaatttata cgaatattgg ggaaatcgta
    19321 tatataaaga actaatcaaa gaaaaaacag ctatcgttaa tctttcatca aatgaataca
    19381 gcaaatccat agaaaaattt attaaagata gtgatacata tattacatgt acttttaaag
    19441 taaataaaaa tggcatattg aaagtagaat ctacacaagc aaagaaagct agaggtatga
    19501 tgacaaaata cattgtaaaa aataggataa gagatattga agaactgaaa aagtttaatt
    19561 tggaaggtta taagtataaa gaaaacttat ctaacaatag tgaatacata tttgtaaaag
    19621 agtagaagtt ttgttaaata ttaaatggca ttgttaaatt taggtaaaat atacttagtg
    19681 tgtattgaat tgaacttgat tttaaaatat aattattctt aaattaaaaa aagaaaggag
    19741 tggtcttcca aaatggaaaa tcacaaacag atgccttggc attcaagagc aacgcatgaa
    19801 attttagaaa gtctagattc atcagaggag gggctcaccg ataccgaggc ggaaaaacgg
    19861 cttaaagaga atggtttaaa tgaacttaga aaaaaaccac ctagaacaac tttacaaatg
    19921 ctttggagtc aaattacaga tgctatggtt atgatactaa taggagcagc aatattatct
    19981 ttgatatttg gcgaatttac agaagctttt gtaatactaa taattgtaac agtaaatgca
    20041 gttattggaa ttgttcaaga gaaaaaagca gaatcatcat tagaagcatt aaaaaatatg
    20101 aactcaccta cagctcgtgt tatgcgtgat ggtgaagaaa atgttattcc agcaagtaat
    20161 cttgtagcag gagatattgt ttttttagaa gatggagcta tggttccagc agaccttcgt
    20221 ttaatagaaa catcaagttt aaaaattcaa gaggcttctt taacaggaga atctgttcca
    20281 tcagaaaaag atgcagatac aatcttacct aaagaatgtg tattaggaga ccgtagcaat
    20341 atggcgtata catcttcaat agtcacatat ggtagaggtg taggtgttgt agtagcaact
    20401 ggtatggata cagaagtggg taacatagca catcttttag attcacaaga tgattttgat
    20461 actcctataa aacgtaaact taatactgtt ggaaagacat taagtgtcat aggtattatt
    20521 gtatgcgttg ttatatttgc aataggtgca ttttatcaga gacctctctt gccaatgttt
    20581 atgattgcaa tttcccttgc catatcaatt attccagagg gattacctgc aacagctact
    20641 attgtaatgg ctttaggcgt acagcgtatg gctaaaagaa atgctttaat tagaaaatta
    20701 cctgctgttg aaacattagg aggagctaca gtaatatgtt gtgataaaac tggtacgtta
    20761 accttaaata aaatgactgt tacacatatt gctgtcaatg gagattttga atctggaaaa
    20821 gtgacatcaa tagatactgc atctgaaaaa catccattag tgtataaaga gattgtttat
    20881 gctggtgcac tttgtaatga tgcatgtatt aatccagata aaacagatga aatattaggt
    20941 gacccaacag agggcgcatt aatttttatg gccaaaaaat ttggaataga tcaagaagct
    21001 cttgaagaag aatatccacg tgtatttgaa cagccttttg attcagatag aaaatgtatg
    21061 acaactgttc ataatataga tgaaaagatt attgcttata ctaaaggagc agtagacgaa
    21121 attcttgacc tatgtactaa aatattaact tcaaaaggtg aaagaaacat tactgaagtg
    21181 gataaaaaga atatacacga attatgtctt aacatgtcta aagatgcatt gcgtgtactt
    21241 ggttttgcta agcgtgagat ttcatctata ccaaaagaag atagtgaaaa tatagaatat
    21301 gatttaacat ttataggtat ggttggtatg attgacccac caagaactga ggtaattgat
    21361 gcagtaagta cttgtaaaga agcaggtata agaaccataa tgataacagg tgaccataaa
    21421 gttactgcca caacaatcgc tcatgagtta ggaatatgga gtgaagaaaa tactgtgata
    21481 tctggtgatg aacttgataa tttgagtgat gatgaactag atgaagctgt taaaaatact
    21541 acagtatttg ctcgtgtatc cccatttgat aaacttagaa ttatacaatc tctaaaaaga
    21601 attggagaag taccagcaat gactggggat ggtgtaaatg actctcctgc cttaaagtct
    21661 gctgatattg gtatagccat gggtataagt ggtacagatg ttgcaaaaga ttcttctgac
    21721 atgattttaa tggacgatag ttttacaaca attgcttatg caataaaaga aggtagacgt
    21781 gtatatagaa acatacaaaa agttatacaa tttttgcttg ttggtaatat agcagagata
    21841 cttacgttgt ttgtagcaat attattaaat tgggatactc cgcttcttgc tgttcatatt
    21901 ctatgggtaa atcttgcaac tgctacgctt ccagcccttg ctcttggagt tgacccacca
    21961 agcagaaata taatgaagca ccagccagtg aaatcaacca ctttgtttga aaaaaatctt
    22021 atacaaagag ttgttaccca aggtatattt gtggcaataa tgactatttt agcatataaa
    22081 attggtctta atatagaaaa tcattctgta ggtcaaacaa tggcattttg tgtattagca
    22141 ttttcacaga tgttacgagc atttagtcag cgttcaaata cagattcaat gtttaataga
    22201 aataatggta aaaatccatt tcttttaatc tcatttttaa cttctgcatt tttaatagca
    22261 gtaatactat ttgtacctgt ttttagaaat gcttttaact taacagtttt aaataactta
    22321 gagtggctta taacgattgt tttagccata atgtctgtaa ttcaagtaga ggttgggaaa
    22381 attattaaaa gaaaaaaatt aaaaaaatag ttgacaaaat taggaaaaat atataagata
    22441 taaaacatag aaaaattaaa taaatcttat ccagagaggt ggagggactg gccctatgaa
    22501 acccggcaac cagtatattt atatacattg gtgctaaatc ctgcggcgaa agctgagaga
    22561 tgagtataat taagcttata cagagcctga gttatatact caggctttat ttattttaac
    22621 tctcatctgg taaatagttt aatttttttt actaaaatct aagggggata caagaatgta
    22681 taataaagaa acaatatgtg tgcaaggaaa ttataaacca ggtaatggag aaccaagagt
    22741 actaccttta tatcaaagta caacttttaa atatagcagt atagaccaac ttgctgaatt
    22801 atttgattta aaagttgatg gacatatata ttcaagaata agcaatccta ctattcaagc
    22861 ttttgaagaa aaaataagtt tactagaggg tggagtatct tctgtagctg tatcatcagg
    22921 gcaatctgca aatatgttgg cagttttaaa tatatgtaaa tcaggagata gtatactttg
    22981 ttcttcaaaa gtatatggag gaacattcaa tttactagga cctagtctta aaaaatttgg
    23041 tatagattta atatcgtttg acttagattc aagtgaagat gagatagtag aacttgcaaa
    23101 ggaaaatact aaggttgtgt ttgcagaaac acttgcaaat ccaactcttg aagtcataga
    23161 ttttgaaaaa atagcaaatg tagctaagag aattaatgtt ccatttattg ttgataattc
    23221 attagcatct ccagtgcttt gtaacccttt aaagtatgga gcaaatatag ttactcattc
    23281 taccacaaaa tatttagatg ggcatgcttc aagtgttgga ggaattatag tggatggtgg
    23341 aaactttaac tgggataatg gaaaatttcc agaattagtt gagccagacc caacatatca
    23401 tggtataagc tatactcaaa aatttggaaa tgccgcatat gcaactaaag caagagttca
    23461 gttgcttaga gactatggaa attgtttaag cccattcaat gcgtatctta ctaatttaaa
    23521 tgttgaaaca ctacatctta gaatggagag acatagtgaa aatgcactta aaatagctag
    23581 atttttagaa aaacatgaaa atgtagattg gattaattac ccaggacttg aagataacaa
    23641 gtattatgag aatgccaaaa agtatttatc aagaggatgt agtggtgttt tatcatttgg
    23701 agtaagaggt gggttagaaa atgccaaaaa atttgtggaa aaattacaga tagcatcttt
    23761 ggttacacat gtttcagatg taagaacttg tgttatacat ccagcttcaa ctactcatag
    23821 acaattaaca gaagaacaat taattgcatc tggagtattg ccttcactaa taagattatc
    23881 tgttggaata gaaaatgtag aggatttaat agctgattta aatcaagctt taaatttcta
    23941 atattctaag agaaagagaa gtgaaaagat atggctttaa tactaccaaa gggattacct
    24001 gttattaata aattattaga tgaaggaata gatgtaattt ataaagaaga ttttaaaaag
    24061 gaattaaagt atgaagaaaa catagacact aagatagcta tactaaatct aatgcctata
    24121 aagatagata cagaattaga tttactaaga aggatagata aaacaggatt caacgtgtct
    24181 gtggaattta ttaaaatttc aacaagagaa agtaaaagaa gttgtaatga atatgttaaa
    24241 gaattttata aaacatttga tgaagccaaa ggagagtatt ttgatggctt tataataaca
    24301 ggagctccag ttgaacaaat ggagtttgaa gaagttgatt attggaatga actagaagaa
    24361 attatggatt attctaagag aaaaactaaa tctacattat atatatgttg ggcagctcaa
    24421 gcaagtcttt acaaatacta caatgtaaaa aaacttccac taagtcaaaa atgttttgga
    24481 gtatttaagc ataaggtaga taaagatagt aaaatagtag atggatttga aaatgaattt
    24541 tttgctccac attcaagaca tactactgta aatattgaag ctttgaaaga gaataaagag
    24601 ttgagcattg tgagtcattc taaagaagct ggtccctata taattacaaa ttcaagggat
    24661 gtgttcgtaa tgggtcatag cgagtatgac aaatacactc ttgataaaga atataagagg
    24721 gatataaata aaggagataa aatatctata cctcaaaatt actatattaa tgatgaccct
    24781 tcagaagagc caactgtaaa atggaaaaaa cattcagaat tgttgtttag aaattggata
    24841 aaaaactatt tgatacaata aattttaaga gtatataaat gttaactaaa aaaatataga
    24901 aatttatagg tataaagtta atcttaatga tactttatac cttatttttt taaaatttga
    24961 ccttataata gtagttttat attttaagaa aatcacttta ggtgtatgta gatagaggtg
    25021 gctttaattt tatatatggt gcgataatgg gagactaaac ctttagagta tcaataaatt
    25081 tgtattttaa cttttaaaag agattaaaaa gggagaaatc agtgtaaaat atatatatcg
    25141 attttttatt aaattttatt aaaaatatcc tgtataaaat taaatatcaa taagataaca
    25201 aaattccaat tgaagttaca atattgtaat tgacaataaa tacttaatac tataatattt
    25261 aatacattaa acattatagt gttaagtatt tatttacagt atgcacttca gcctaaattt
    25321 gaaataaagt attttcgtag ggagcgtttg tatggatgag atgagtttta agaaagagct
    25381 actagagttg actagagata taaatatgaa atttacaact ttattaagtg atttttatca
    25441 gccacttggt attacagcag tgcaagcttt gattttatct gagttatgtg aacatggaga
    25501 gaaaaaaata agcgatttag ggaagaactt aaacatgaca aatagtaatg tatcagtaat
    25561 ctgtcaaagg cttgaaaaaa atggcttttt aaatcgcata agagatatag aagaccaacg
    25621 aattgtaaaa gtaaaagtta caaataaatc attggatata caagaacata tttcaagtag
    25681 tatttttgat agttattttg aaaatatgac cagtgaaaaa ttgcaagata tggaagatat
    25741 aatagaaggt ttagagaaat taaataaact tttaacttac attgattgca aataacataa
    25801 aaataattta aaggagaata aaattatgga tgaacataaa ccccaaaaaa ggtcagcact
    25861 ctattattat acagttataa taatagtagt aatgttttta aatgctttaa tatttccaag
    25921 tttaatggat aaaaaaatgg ttgagattga ctatggaaag tttctcacaa tgttggatac
    25981 aggaaaggtt aaatctgttg agatagaaaa taatagaata gcaataaatc catctagtag
    26041 caaggataag aatatataca taactggtag aatggatgac ccagaattgg tagatagact
    26101 aaaaaatgca aaagtagaat ttactaaggt tattcctaag gaaaattcac ctcttttaag
    26161 tattttactt acatggataa tacctatagg tattcttatg ctatttggta acttaatgat
    26221 gaagtctatg caaaagcgaa tgggtggtaa tgctatgcaa tttggaaaaa gcaacgccaa
    26281 aatgtatgta tctgctcaaa gtggaaaaag atttaatgat gtagctggtc aagatgaggc
    26341 aaaagaagct ttaactgaaa tagtagattt cttacacaat ccagaaaagt ataaaaagat
    26401 aggagcacaa atgcctaaag gagcactttt agtaggacct ccaggtacag gaaaaacact
    26461 ccttgcaaaa gctgtagcag gtgaagcaaa tgtaccattt ttctcaatat ctggttctga
    26521 gtttgttgag atgtttgtag gaatgggagc ttctaggatt cgtgatttat ttaaacaagc
    26581 aaaagaaaaa gctccatgta tagtgtttat agatgagatt gatactattg gtaaaaagcg
    26641 tgataatgga agtggattag gtggaaatga tgaacgtgaa caaactttaa atcagttgtt
    26701 aagtgagatg gatggttttg atggtggaat tggagtagta atacttgctg ctacaaatag
    26761 acctgacagt cttgacaaag cattacttcg tccaggaaga tttgatagac gtataccagt
    26821 tgaacttcca gaccttggag gacgtgaagc tatattaaag gtacatgctc aaaatgtaaa
    26881 tgtaagctca gatatagatt ataatgcaat tgcaaggtct acatcaggag catcaggtgc
    26941 agaacttgca aatattgtaa acgaagcagc acttttagca gttaagtctg gcagagatat
    27001 agtagaacaa caggattttg atgaatctgt tgaaactgta attgctgggt atcaacgtaa
    27061 aggagctgta atttcagata aggaaaagaa aattatagca tatcatgaaa taggtcatgc
    27121 acttgttgct gctatgcaaa aacattctgc acctgtccat aagattacta taatacctag
    27181 aacttcagga gcattgggat atactatgca agttgctgaa gatgagagtg tacttatgtc
    27241 taaagaagaa gcaattgata aaataactac ttttacaggt ggtcgtgctg ctgaagaggt
    27301 tatctttaac acttgtacat caggagcatc aaatgatata gaacaagcta ctaaaattgc
    27361 aagagctatg gttactcgcc ttggtatgag tgaagagttt gatatggtcg ctcttgaaac
    27421 tgtaagcaat caatatttag gaggagatac ttctcttgct tgttcttccg acactgctgc
    27481 taaaatagat gaagaggtat ttaaaatagt aaaggcttgt cacaaaaatg caattgaaat
    27541 cttagaaaat aatattgata aattgcatga acttgctaat tatttattag aaaaagaaac
    27601 tattacaggt gatgagttta tggaaatact taacttaaac taaaatgatt atacacaaga
    27661 taaaaatgcc tattgttagg catttttatt ttacaactaa attttttaaa ttcatattta
    27721 aatctttaca taatcttaat cattaaaaat acatcttaac tacaatttta tatcggaatt
    27781 gatattataa tagtaatgaa tggtgtaagg aggtttttta atggatagac ctaatcctga
    27841 tattctatta gaaaaaatta aaaatgaaga agaaaaacta agtagaggtc aattaaaaat
    27901 attctttggt tatgcagctg gagtaggaaa aacctactct atgttggaat ctgcacaaaa
    27961 tttaaaaaaa gtgggtgtag atgtagtagt tggatatatt gaaccacaca ctagaccaga
    28021 aacattggct ttacttgatg gcttggaaat tcttcctgta aaggagatag aatataaatc
    28081 tataaaacta aaagaatttg atttagatgc tgctttagca agaaaaccag aagttatatt
    28141 agtagatgaa tttgcccatt ctaatgttgc tgggttaagg catacaaaaa gatggcaaga
    28201 tatagaagaa ttgctgttag caggcataaa tgtctacact actgtaaatg tacaacattt
    28261 agaaagtcta aatgacattg ttgagataat tacaaacgta tcagttaaag agactatacc
    28321 agataagttt ttggatacaa atacacagtt agaacttata gatgttgaac ctgatgtact
    28381 tcttgaaagg ttcaatgaag gtaagatata taagaaagaa caagctacta gagcaaaaaa
    28441 taattttttt ataaaagata acctggttgc acttagagaa atcgcactta gaaaaactgc
    28501 agagagagtt aataaagaag ttcaaatgac cagactatca aagggtgatg taactgtaat
    28561 acctacatca gatacacttc ttgcatgtat aagtccatct ccatcttcag caaaagttat
    28621 tagaactgca tccagaatat cagacagtac atttgcaaaa tggatagctt tatatgttga
    28681 aactccaaac acagcaagac ttccatttga tgaacaaaaa caactacaaa ataacctaaa
    28741 attagctaag aaattaggtg gagaaataat tgttttacat ggtgaaaata taatagagca
    28801 aatacttaga attgcaaagc tgagaaatgt aacaaaaatt gtaataggta gaaatcattc
    28861 aagtaataaa agatttagta aaagatttaa aaaagatata gttgacaaat taattgatga
    28921 agttgattat atagatatac atataattcc atataaattt gcctcagatg ttaaatacaa
    28981 acctaaaaag gataaatcat caataaaatc taaatttaaa attagcaaag ttgattttat
    29041 aaaacttata tttattactt tgatgataag tattttagca tatgcagtac aaagcatggg
    29101 atttataaga gaaaatatat tgttaatata tatgttgggt gtagttttag tttctatgtg
    29161 gactaaaggg tatagtacag gtataataag ttctgtattt aatatagttc ttttaaatta
    29221 tttttttaca gcaccattat atacattatc tatagcagat tcaaactata tagtaacact
    29281 ggttgtattc tcaatagtag gtataataac tagcactctt acgtctaaga tacagcatga
    29341 agcagaaact gctgctaaaa gagaagaaaa tacaaaaatg atatatcaaa taattaaggg
    29401 atttttaaga ttatcaaata aagatgatat agtaaacaaa ggtatagaac ttttgtctct
    29461 tagcttaagt agagatgtaa tttgttattt aaatgtagat aagcataata aatcaaagct
    29521 ttacaaaaaa aatactaata ataaggataa aaatgatttg gatagtgaag atgaaaaagc
    29581 tgttgcaagt tgggttttat ccaattcaac agtggcagga aatgacacgg atacacttcc
    29641 tggttcaaag ggatactata taccaattgt aggaatgaat ttaactttag gagtagtggg
    29701 aatatcatgt attgattcaa aattggatac agaagatata agcttaattg aaacaataat
    29761 tgctcaaatg gcaatagcgc ttgatagaga aatcttgtca gaagctaaag aaaataccaa
    29821 tcttgagatt gaaagggaaa gattaagaag taatctttta agagcagttt cgcatgacct
    29881 tagaactcca ctagcaggaa tatctggtgc agtaagtaca attataaaaa acaagggtac
    29941 tataggtcaa gatataatag atgaattact tagtggtgta tatgaagata ctcagtggtt
    30001 aataagactt gttgaaaatt tacttagtat gaccaagata gatgaaggaa aattggaagt
    30061 taaaaaacat tctgaactgg ttgaggaaat tatatcagaa gcgttacaaa aaataaaaaa
    30121 aagaattgaa aatgcactta tagatattaa tataccagaa cagatattat ttgttcctat
    30181 ggatgcaaaa ttaatagaac aagttttaat taatttaata gataattctt tgaaatattc
    30241 aaaggaagat tgtaagatag agataaatgt atatgagaaa gatgattatg tttggtttga
    30301 agtatctgat aatggtcctg gtatatcaaa ggaacttaaa aagcatatct ttgacagatt
    30361 ttttactgga gaagaaggag ctaaagattc cagaaagggt gttggacttg gattatcaat
    30421 ttgtaaatct ataattcaag ctcataaagg tgaaattatg gtagaaaaca ataaagataa
    30481 gggttcaact tttaagttta gtttgcctaa ggaaaatgaa tagttttaaa ttttaaaatt
    30541 agttttggag gaagaaatga gtaaaaaact tatattgtta gtagaggatg ataagacaat
    30601 aagaaaattt atatctactg cacttttaac acaggattat gatgtcaagg aggctataac
    30661 tggaaaagaa ggtatatcta ttgctgtctc atattctcca gatgttgttc ttttagattt
    30721 aggcttagaa gatatggatg gaatagaggt aataaaagct atcagacaat tttcaaatat
    30781 accaataatt gtagtttcag ctagagagca agatagagac aaggtagaag tatttgatgc
    30841 aggggcagat gattacttaa caaaaccatt ctccatagta gagttattag caagagtaag
    30901 agtagcattt agacattcac aagtagaagc tcaacaaaaa gatgatgtta aatctacgtt
    30961 tgaagtagat aaattattga ttgattttga taaaagaaaa gttattgttg atgatgttga
    31021 agtccatttg acacctattg aatataatat tctttcatta cttgcaaagc atcatggaaa
    31081 agtgcttact cataatttta taataaaaga aacatggggt agtgttatag ggaatgagac
    31141 taagtcttta agggtcttta tggcaacgtt aagacgaaaa atagaaaaac aacctgcaaa
    31201 cccaagatat ataattacag aagttggtgt aggatacaga ttaaatgatg aatagttgta
    31261 atatattaat tattagatta tgtgcttatt aatatatatt aaaattatat agtttagtta
    31321 aaataagaat gaagtgtatg tgcttgttgt cagtttagca catgcatttt attttttagc
    31381 ttttttagta tcaataattt tttagtatca ataatatgaa atatgtttta aaataagtat
    31441 atagtgtaat ctgtaataaa aactttggtt aaataataaa tgtatttaac acttacctta
    31501 taataaattt aatataaata ttaaataata attattaaaa tagtgtaaaa taattacagt
    31561 aaggattata aaaaattttt agaatgtaaa ttgaaattta ggagtagatg tatgtatata
    31621 ctgaatttaa atacaagaga gactattgaa gattttagag ataaatttta tgtagcagaa
    31681 aattcttatc ttatattaag tgctccaaaa aatttaaaat tgcttaagga aactttggat
    31741 atagatgaaa taacttttaa tgattgtctt aaatttgatg aaataaccaa acttgattta
    31801 tttgataatt acgatttttt aagcctaaat acatttgaac taagagatgg agaagctgtt
    31861 atagaagagg taaatatgta tttatcagat aattttatat tggttgtagt gaatgaagaa
    31921 cactttttat ttgaatttgt aaaaaatatt attttgaaga actctcaact tgaaaaaaat
    31981 ccagttatta atctatttaa gataaactac ttgattctta gagaagttat aaaaaatggt
    32041 tttgagtctt tggaaaaagt tgaagagtta attcttcaaa tagaagatga aatgatggac
    32101 aacattaata agaatcatgt atctagaata agtgatgtaa gaggattaac aagaattata
    32161 gttaagaata ctagacctct tttgtatatt ggggatagaa tagttaagga aaatataaga
    32221 tatttaaaat attcaaatgt aaaaaaatat aatttagaaa attttcaagg tatagatttt
    32281 ggaattgaca aattatacaa tttcgcattg tcaacacgag agttagcaga taaattatta
    32341 gatatttatt cttccagagt aggtgagaaa acaaataact taattacaaa attaaccttg
    32401 ttaacagcca tatcagcacc acttacaatt ataactggta tatatggaat gaactttaga
    32461 tatatgccag aattaaactg gatttatgga tatccagcaa ctttattttt tatgctatgt
    32521 ataatttttg ttggaattat aatatttaaa ataaaaaaat tattgtaaat tacagatgat
    32581 gtttaattga ttttataaaa atacatcaat tgagaagctg atttaagtaa ataaaaaaat
    32641 attttaaatt gaaaatattt atagaaaata ttgacaatta tattttcttt gttataatta
    32701 ttaaacaaga agaataataa attataaaaa tggaggataa tactatgaaa ggaatattaa
    32761 aagaactaac agcaaaactt tatagctttt tttactttat gttctggggc ttttatttta
    32821 gcgctggcta tttcttttac aaaaatatat gtacttcctt tctggtgagg ccttatttta
    32881 gtgattttga gcataagtaa attttataaa aatgattatt ttatatattt atataagatt
    32941 tagtgcttga tagattattt tagagaactc attagtgagt tctctttttt attttaaata
    33001 taaaattata atattgggag gtagtaaaaa tgatagtagt attaaaaatg ggagcagata
    33061 aaaatgaagt taaaaaatta attgaggcta ttgggagaga aggagtagaa gttaatccca
    33121 tagatggaac agaattaact gttttaggtt tagttggaga tactagtaaa atagatgcca
    33181 aaagaataga agcaaataag gtagttgaaa aagttatgca tgtggtagag ccttttaaaa
    33241 aggccaatag aaaatttcat ccagaacctt caatcataaa tgttaatgga atggaaattg
    33301 gttcaaagaa aattgctatg atagctgggc cttgttctgt tgaaacagaa gaccaaatag
    33361 tatctatagc taaagatgtg aaaaaatcag gtgcaggatt tttgagaggt ggagcattca
    33421 aaccaagaac atcaccatac gctttccaag gattgaaata tgatggattg gatttattaa
    33481 aaaaagcaaa agaaaaaaca gggcttccta tagttacaga aataatgtca acacaagata
    33541 tagatatatt tgaagaaaat gtagatgtaa ttcaagttgg agctagaaac atgcaaaact
    33601 ttgatttatt aaaagaatta ggtaaaacaa ataaaacaat acttttaaaa agaggattat
    33661 ctgctacaat tgaagagtgg ctaatgtcag cagagtatat aatggctgga ggaaatgaaa
    33721 atgtagttct ttgtgaaaga ggtataagaa cttttgaaac atatactaga aatactttgg
    33781 atttaagtgc aattttagct gtgaagaaac ttagtcattt accagttata gttgacccaa
    33841 gtcatgcagc aggtaaatca tggatggttg actctttatc taaggcagca attgcagttg
    33901 gagcagatgg tctaataata gaagttcata atgacccagc acatgcactt tgtgatggaa
    33961 aacaatcgat taagccaaat gaatatgatg aattgataag tgaattaaag actatcgcat
    34021 cagcagttgg tagagaaata taatctataa aaggatggtt aaacgtggaa gaaaaactat
    34081 tagtaaattt aaaagaaaat agctacaata tatttattaa aaaaaatata ctaaagaata
    34141 taggagaaga aataaaaaaa atatattttg gaaataagat ttttattgta actgatgaaa
    34201 atatagcaaa attatacttg gataaagtaa aaaataattt aagtgaatct ggatttgaaa
    34261 ttaaatcttt aatattaaaa tctggtgaag aaacaaaatc atttaatact cttcctaaaa
    34321 tatacgatag tttacttgac tttaagttaa ctagaaaaga tttgattatt actttaggag
    34381 gaggggtaat aggtgattta ggtggatttg cagcagcaac ttttttaaga ggtataagtt
    34441 ttattcaaat tccaacatct ttattagcac aagttgatag ttctgtaggt ggaaaagttg
    34501 gagttgacct tgagagaggc aaaaacttag tgggaagctt ttaccaacca aaggctgtgt
    34561 ttatcgaccc aaatgtatta ttatcacttc cagaaaaatt ctatagagat ggaatggcag
    34621 aagttataaa atatggatgt ataaaagaca aaactttttt caataaactt ttaagtttaa
    34681 aaaatagaga agaagtaatg caacatatag aatacattat acataaatgt tgctttatta
    34741 aaaaaactgt agttgaagct gatgaaaaag actttggaga tagaatgctt ctaaactttg
    34801 gccatacatt aggtcatgct attgagaaat actacaattt tacaggttat acccatggag
    34861 aagctgttgc cataggaatg tataagataa ctttagaaag tgaaaagata ggaattacaa
    34921 aaaaaggtac atcagaactt ataaaatcaa ttttaatgaa ttataatttg ccttatgaga
    34981 ttgaattaag agataataaa tctatagtag atgctatatc tcttgataaa aaaaatctag
    35041 gtgatacatt aaaaataata cttttaaaag atattggaga gagtattata tataatacta
    35101 cttctaaatt ttttcaggag gtaagataat gggaagtcta aaaatatatc caagtaaatt
    35161 atctggagat gtaaaaatac caccatcaaa aagtatggca catagggcag ttatttgttc
    35221 atctctaagc aatggaaaaa gtagaatttc taatatagat ttttctgatg atataatagc
    35281 tactataaga gcaatgacat cattaggagc tattatagaa aagaaagaag atattttaga
    35341 aatttcggga attttttcta aagaaggtat tttaaataga gagaatcagt tgaatcaacc
    35401 taaattgaca atagattgta atgaatcagg ctctacattg agatttttag tacctatatc
    35461 tttaacattt gatggtgtaa aaaggtttat aggtagaggt aatcttggaa aaagaccact
    35521 tgatacctat tatgagatat ttgacagaca gaatataaaa tatagttaca aagaaaatca
    35581 gttagatttg attatatcag gtaagcttaa accagatgaa tttagagtaa aaggaaatat
    35641 aagttctcag tttatcacag gtttactgtt tatattgcct acgctagaaa gtgattcaaa
    35701 gataataatt actactgagc tagaatctaa aggatattta gatttaactc tttcaacgat
    35761 aaaagatttt ggggtagaaa ttataaacaa taactataaa gaatttatta taaaaggaaa
    35821 tcaaacgtat aaagcgagag attataaagt agaaggagat tattctcaag gagcatttta
    35881 tttatcagca gatgctatag gagaagatat tagcatatta gaccttaaag aagattctct
    35941 tcaaggggat agtgaagtag ttgaaatttt atctaggatg ggaatggaaa tattaagaga
    36001 aggcaacaaa ataaaaggaa taacaaatgg tttaaatggt actttgatag atgcatctca
    36061 atgcccagat ataatacctg tattatctgt agtagcatcc ttaagtatag ggaggactac
    36121 aataattaat gctggtaggc ttagaattaa agaatgtgat agacttcatg caataaatgt
    36181 tgagttaagt aaacttggag caaatataga ggagaaagag gatagtttga taatcgaagg
    36241 agtaagcaag ttaaatggtg gagtagaggt gtggagtcac aaagaccata gaattgctat
    36301 gacacttgca attgcttctt gtagatgtga taaaccaata atattaaaag attttgagtg
    36361 tgtatcaaaa tcttatccac atttttttaa agattttaag atgttaggag gtcgaattga
    36421 tgagtggaat atggggaaat aatttaaaag tatcaatttt tggagaatct catggaaatg
    36481 ctataggtat aaatatagat ggtcttcctt cggggatgga acttgacctt gataatattg
    36541 ataaagaaat gaagagaaga gcacctggaa aaaattctat atctacttca agaaatgaaa
    36601 gtgatatacc agaaattcta agtggatatt ttaatggaag aactacagga acgccattat
    36661 gtgcaatcat aagaaatagt gatactcgtt caaaagatta tggagagctt aaaaatttaa
    36721 tgagaccagg acatgcagat ttcacaggta atgtgagata ttctggattt aatgactata
    36781 gagggggagg tcatttttca ggtaggataa cagctccatt agtattttgt ggggctatat
    36841 gtaaacaaat tttatcacaa aaaggaatag agataggagc acacataaaa aaaattaaaa
    36901 atatagaaga tatgagtttt gattatgtaa atatttcaaa acaacagtta tcaaatttgc
    36961 aaactttgga actaccttta cttgatttat caaaggaaga agccatgaaa aatacgatta
    37021 tagatgcaaa aaatcaagga gattcagttg gtggtataat tgagtgtgca gtagtaggta
    37081 ttaatgtagg gcttggaaat ccattttttg actctgttga atctacttta tcacatttat
    37141 tgttttctgt tcctgctgta aaaggtgtag agtttggttt aggttttgaa cttgcagata
    37201 tgtatgggtc tcaaagtaat gatgaaatgt attatgaagg aaatcaagtt aagagcaaaa
    37261 caaataacaa tggaggaatt ataggaggga ttactactgg aatgccaata attttcaaag
    37321 tggcaattaa gccaactcca tcaattagca gacaacaaaa cacagttaat ataaaagata
    37381 aaaaggacga tattttatat attaaaggca gacatgaccc ttgtatagtt caaagggcta
    37441 tacctgtaat agaagcagta acagccattg gaatttttga tttgatgaaa ggacgataat
    37501 aatggaggat ttaacgagat atagaaatga gattgacaat atagataaag agcttattca
    37561 attatttgaa aagagaatga atacagttct tgaaattgcc agacataaaa tgaaaaataa
    37621 cactactata cttcaaaaag atagagaaga aaaagtacta agtagagcct tagataattt
    37681 agataataaa gcatattcac aagaaacggt acagtttttt aattctataa tggaaattag
    37741 tagaggatta caaaaaagat tgatagataa tgatggtgag cagaaaatcg agtttagttt
    37801 agattcatca aataagaaat ttgatttgtc aaatgtaaat agatataagt ctttaaaaga
    37861 tgaattaaat aaaaaaaata tcctagtagg gtttccagga aaatcaggtt catttacaaa
    37921 agaagcacta aataaattct tcaacaaaaa aatatcaaaa aaacaattta aagaatttga
    37981 agatgttttc atagcactta aaaataaaga aataaactat ggaataatcc ccatagaaaa
    38041 ttcatctaca ggagctatct ctgaaactta tgaccttttg agaaagtacg gtttttatat
    38101 agttggagaa gaatgtataa aaatagacca aaatttaata gggataaaag acacaaagct
    38161 tgaagatata aaagaaatat attctcatcc acaaggtata ggacaatgta gtgaattttt
    38221 aaaacaaaat agtacatgga aattgatacc atttaataac acagcaacaa gtgcagaact
    38281 tgtaagaaaa cttcaagata aaacaaaagc agcaattgca agcaaaaaag ctgcaagtat
    38341 ttatggatta gaaataataa gtccttgtat aaatgatatt gcaaacaact atacaagatt
    38401 tgtagtaatc agtaatcaaa tacacattga agaagaatca aacaaaatga gtgtagtatt
    38461 ttctgttgaa catgaagcag gaaaacttta taaagtactt ggatactttg ctaaaaataa
    38521 tataaatatg acaaaaatag aatcaagacc tatgaaaaat gcctcatgga gatatttctt
    38581 ttatatagat tttgagtgtt ctatatacaa tgctaaagtg tacgatttat tagaattgat
    38641 agaacataat acagcatatt ttaaatttat gggagtatat aaaaataaaa ctgaatagat
    38701 aagataaatt tttatttaat ttataattat taggaggtgt aagtatgaat tttttcggtc
    38761 tagtaggtga aaaactctct cacagtgttt cacctcaaat ccacaagaga gtattcgaga
    38821 tattgaatat tgaaagtgct tataaaaact ttgaaatttc aaaagaagat atatctaagc
    38881 tagacggtgc tataaaatta ttaggaatac aaggggtaaa tgttactgta ccatataagg
    38941 agcgtattat gaaatatctt gattttatat caccagaggc aaaacgtata ggagcagtta
    39001 atacaatttt acttagagaa aatatgttat atggttacaa tacagattac tttggtcttg
    39061 atagtatgtt taaaatggct aatattgatg ttcaaggaaa agtagcagtt atattaggaa
    39121 ctggaggtgc ttctaaagct gctcttacat attttattga ttctggtata gaaaagcttt
    39181 atgtttcaac tagaaaaaag gatgataaaa aattattaaa tagtaaagct atattaatag
    39241 attatgaaga acttaaacat ataaaaggag atataatatt aaatgctaca ccagtaggta
    39301 tgtaccctaa tgtaggaatt tcaccagtgt caaaatctat tatacaaaat tttgatatat
    39361 taatagattt aatttacaat cctggagaaa cagagttttt aagaattggt aatagtatgg
    39421 gtaaaaaaac ttgtgatgga ttatatatgc tggtggggca agcaataaaa tctcaggaaa
    39481 tttggcaaga tactaaaata gataatagta ttttagatgt tatatataat gaactaaaat
    39541 tagaattttt gtaaaggaga ttgttatgat aaataaaaca aaagaaaaat tgatattaat
    39601 aggtatgcca ggtagtggaa aaactacaat tggtaaactt ttggccaaag aatataattg
    39661 tagtttctgt gatatggatg attatataat tcaaatatct caaaaaagta tagcagagtt
    39721 gttttcagaa ggagaagata tctttaggaa ctatgagact caagcatgta gagaactttc
    39781 tataagtgat aaaacagtga tatctacagg tggaggtgta ataaaaaagg atgttaatat
    39841 ggaaatacta aaagaaacag gtataataat ttttattgat agacctatac aaaagatttt
    39901 ggaagatata aatattaatt caagaccatt attaaaaaac ggaaaagata gattgtataa
    39961 tctttacaat gagagaataa atctttataa aaaattttca gatatagaga ttttaaatga
    40021 taaatcatta aataatgctg tatataatat tacaaatgca gtcagtgaaa attttaaatt
    40081 tgactttaaa gaaaaataat ctagggggaa gtaaaaataa tgaatattgt tattgtagga
    40141 ctaggagtta taggaggctc ttttgctaaa gcattaaaaa aagctggata tgaaaatgta
    40201 tttggagtag atgtagattt agaaacttta aaaaaagcag aaaaagcaaa aatcataaaa
    40261 aaaggatgta ctacaggtaa agagttattt aaaaaagctg atttaattat actatctata
    40321 tatcctagat tagttgtaga ttttctaaat aataataaaa acttttttaa aaaagggact
    40381 ataattactg atactacagg aataaaagaa acacttatca atgatgtgtt gcaaattatt
    40441 ccagatgata tagattttat atttggacat ccaatggcag gtagggaaaa aaagggtatt
    40501 gattttgcaa gtgaacaagt ttttaatggt gcaaattata taattactcc aactggcaga
    40561 aacaacataa aaaatttaga gttagttgaa aatttaattt tagagattgg atttaaaaga
    40621 gtaaaaaagt taacttcaca aaaacatgat gagattatag cttttacttc tcagttacct
    40681 catgttatgg cagttgctct tataaatagt gatgaagaag gtagagatac gggtaaattt
    40741 attggagata gttatagaga tttaactaga attgcaaata tgaatgaaga cctatggagt
    40801 gaactttttt taggaaatag agataattta ctaaaagtta tagaaaactt tgaatcagaa
    40861 gtaaatttag taaaagaagc tatatttaac aatgataaaa ataaatt
//
LOCUS       DAFAZV010000040        38571 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFAZV010000040 DAFAZV010000000
VERSION     DAFAZV010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 38571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38571
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.040"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..617
                     /locus_tag="KOU88_002767"
     CDS             <1..617
                     /locus_tag="KOU88_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HBK3212635.1"
                     /translation="FIAFNYNQLPDSIATHWNINGSPDVFIDKSFLNVFKLIGTDFCL
                     MVLLYITSIGSIKSRIKIDTNRIEESRVENIKYLNKIGYLFLILMIIMTTQFFTTLLS
                     IKTKLSTAMNITTLLVIIYLIATYINSPNLKFNSSYSPEEDEKYWIAGIMYNNPNDPS
                     LMVNKRFGIGWTINFGNPLGKILYIAIALLLIFSLFSLIKSLLL"
     gene            737..1213
                     /locus_tag="KOU88_002768"
     CDS             737..1213
                     /locus_tag="KOU88_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK3212636.1"
                     /translation="MLSKAEIKYFNECASEILSSEKVQLMRTFPHHGNVSCLEHSLSV
                     AYYSYLLCKKLHLSVDIQSVIRGALLHDFFLYDWHYKGDRKGLHGFTHPREALKNATL
                     FFQINEKETDIILKHMWPLTVKPPRYKEAFIVCLLDKFCCLVETLKIHSLLSPYHV"
     gene            1599..2066
                     /locus_tag="KOU88_002769"
     CDS             1599..2066
                     /locus_tag="KOU88_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HBK3212637.1"
                     /translation="MFKEMRLKKREMTKEDTVEVLKNGEFGTFSTISENGYPYGVAVN
                     YVYFNDSIYFHCARNGHKLDNISKNNKVSFLVVANESVIPDKFSTTYSSAIVFGKACT
                     VENEEKKNALVEIIKKYSKGFFEEGMKYIEKDMNLTTVVKIEIDHISGKASRL"
     gene            complement(2126..2698)
                     /locus_tag="KOU88_002770"
     CDS             complement(2126..2698)
                     /locus_tag="KOU88_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBK3212638.1"
                     /translation="MKVAVIFHSVCGSTYLLAREYKEALEEMNIEVDIFRVSDEVAKT
                     LPQYYLINSKEYKDEFESINVIKSGKEILDYDAIFMGSPTYYGNVSGPMKMFMDSFSD
                     IWVGAPLSGKIFGCFATAGSQHGGGELALQAMNIFAQHMGMTLLSVPCSVRGGYPAYG
                     ILHIAGDNSDIRPNDDAKIGIRDYLKRLNI"
     gene            complement(2761..3858)
                     /locus_tag="KOU88_002771"
     CDS             complement(2761..3858)
                     /locus_tag="KOU88_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBK3212639.1"
                     /translation="MLLKSLTRKIEKKYPLNLAEDWDNVGLIVGDFDMDVKKVLVSLE
                     ANEDVIDEAISKNIDLIVTHHPFIFGKINKINSGDLKGRLIQKLIKNDISLYSMHTNF
                     DIAFDGLNDYFMEIMEFGNSKVLDITKSENLYKLAVYVPHNYSDELRKVLSNSGAGHI
                     GNYSDCTFSTEGEGQFKPLEGSNPFLGSVNDIETVNEVKIETVVPQKLLGGVISSMLD
                     AHPYEEVAYDLYKLENKGEIFGLGRISKFDKSMTLESLSRKIKEKLNMKHIRVVGNLS
                     TDITKVAVVTGAGSEFVKKAKRQGAEVLITGDVKYHEAQDALDIGMCIVDCGHFDTED
                     IFKNVMKRFLDEFSEIEVIKSNVYLNPFSTI"
     gene            complement(3872..4561)
                     /locus_tag="KOU88_002772"
     CDS             complement(3872..4561)
                     /locus_tag="KOU88_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBK3212640.1"
                     /translation="MKLTDRLLKIASLVSDGKKIADIGTDHGYIPVYLLKEGKVPFAV
                     LADVNKGPLDNAHKEVIQNNLLDKVDLRLGSGIEILEIGEVEEVIIAGMGGILISELL
                     EAKKEVAHNVEKLILQPMQAQEELRYYLLNNGYEILEEVLVREDFRIYEIIVAKYTGK
                     NTIIEDEIYYEVGIKLLENKDSLFNDFIEKKIKTYSSIVNKLEGKNGEAIDKKRKESE
                     VAIKKLENLIK"
     gene            complement(4726..5892)
                     /gene="rpoD"
                     /locus_tag="KOU88_002773"
     CDS             complement(4726..5892)
                     /gene="rpoD"
                     /locus_tag="KOU88_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBK3212641.1"
                     /translation="MENKSNKKELKKVTAKTLIEKGKKQGSLTLAEIMEAFSETELDK
                     DQVENLYETLGNLGIEITETKNYKADIDFSVADDDLSIGHLDEDAEAISHDDSSAIEI
                     ETVDLSLPKGISIDDPVRMYLKEIGKIPLLKPHEEVEFARRMHEGDEIAKQRLVEANL
                     RLVVSIAKRYVGRGMLFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAITRA
                     IADQARTIRIPVHMVETINKLIRVSRQLLQELGRDPKPEEIAKEMEMTEDKVREIMKI
                     AQDPVSLETPIGEEEDSHLGDFIPDDDAPAPAEAAAYSLLKEQIEDVLGSLNDREQKV
                     LKLRFGLEDGRARTLEEVGKEFDVTRERIRQIEAKALRKLRHPSRSKKLRDYLD"
     gene            complement(5910..7700)
                     /locus_tag="KOU88_002774"
     CDS             complement(5910..7700)
                     /locus_tag="KOU88_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBK3212642.1"
                     /translation="MNDIKDIIEEIKARCDIASIISEYMNIKQSGANYKGLCPFHGEK
                     TPSFYINTSKQIYKCFGCGEGGDVINFVMKMENLDFMDAVKILANKCGIEINTNMNEE
                     TRIKIEKSKKFQDIHTEAARFYLSNLLGSKNLGYEYLRIRGLDDKIIKKFGLGFSLDS
                     WNSLMNTLISKGYKKQDLLECGLIAKNRDGTNCYDKFRNRVMFPIFDYRGNIIGFGGR
                     VLDDSLPKYLNSPDTLIFNKKQNLYGLNFARKNLESKTIVLVEGYMDLISLYQYGIKN
                     VVATLGTALTEQQGILIKRYADTAIISYDSDEAGIKATLRAIDILTKLGINVKVLDLK
                     DAKDPDEFVRKYGLSDYKKAMDVSTHYIKYKIDHLKKEFNIQKDEERVKFAKEASKII
                     KQLTSPVEIDFYTKYLSNQIDINVESIKREVYGKNYNKPYNNKNQKKIEEKVIEKVEV
                     RQDGKQLVEETLIKIMLEDKKIREIALLKVEESDFLLKESKEILNYMIKNQELDKITI
                     DKLKSLNISEEYLKELNSISLNSINLENTKEIEGIITNIRKNSLEEQINSLLREQQEL
                     ENNNDMKEVDGRVMEIALKIVEINKILKSL"
     gene            complement(7955..8740)
                     /gene="aroF"
                     /locus_tag="KOU88_002775"
     CDS             complement(7955..8740)
                     /gene="aroF"
                     /locus_tag="KOU88_002775"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBK3212643.1"
                     /translation="MKENLFNNNSKIEINTNNKKITVKKDKLIIAGPCAIESYEQLLE
                     TAKFVKRQGANILRGGAYKPRTSPNSFQGLKKEGLEILKAVKDEVGMAVITELMDVRD
                     MDELYSISDIIQIGSRNMQNFTLLSEVGKQNKPVMLKRGIASTITEWIGASEYIAIEG
                     NSNIIMCERGIRTYNDYTRNTLDLAAVPIIQKETGLPVVVDPSHATGVRYLVKPMSLA
                     SFACGADGIMVEVHPDPENALSDGAQSLCFNEFEDLMKSINNY"
     gene            complement(8721..9227)
                     /gene="folK"
                     /locus_tag="KOU88_002776"
     CDS             complement(8721..9227)
                     /gene="folK"
                     /locus_tag="KOU88_002776"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBK3212644.1"
                     /translation="MNKAYLGIGTNMGDRFDNLSRACELLKNSDSIYKVKESSLYETK
                     PWGYTEQADFLNMCVEIETEFEPYELLEYCQEIERELHRERIVHWGPRTIDVDVLFFN
                     DVVSTDERLTIPHPRIQDRAFVLIPLMDLNEKLIINEKTIKEHLNLLSAEEREEVKEL
                     VGYERKPI"
     gene            complement(9220..9585)
                     /gene="folB"
                     /locus_tag="KOU88_002777"
     CDS             complement(9220..9585)
                     /gene="folB"
                     /locus_tag="KOU88_002777"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HBK3212645.1"
                     /translation="MDKILLSNLGFYGYHGVLKEENFLGQKFFVDMELYIDSREAGLS
                     DDINKSVSYAEVYNVVKDITENKQFNLLEALAENIAEEVLNKFILINGVMVRVRKPEA
                     PVNGIYDYFGVEIRRTRDE"
     gene            complement(9596..10387)
                     /gene="folP"
                     /locus_tag="KOU88_002778"
     CDS             complement(9596..10387)
                     /gene="folP"
                     /locus_tag="KOU88_002778"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBK3212646.1"
                     /translation="MFDYGKRTYIMGILNVTPDSFSDGGDFNNLDIAIQHAKDMVDQG
                     ADIIDLGGESTRPGHSYVDSDEELRRVIPVIKKLKQELDIPISIDTYKADVAEEALKL
                     GVTMVNDVWGLRKDKNMASVIGKYDAEVCIMHNQDGTNYDKDIMESIKDFFKVSIEMA
                     MSCGVKKEKIVLDPGVGFGKDFEQNIEVLRRLNELKDLGYPILLGTSRKSVIGKVLPV
                     EPKKRLEGTIATTVLGIRDGVDIVRVHDVYENLMAARMTDAIYRK"
     gene            complement(10451..11023)
                     /gene="folE"
                     /locus_tag="KOU88_002779"
     CDS             complement(10451..11023)
                     /gene="folE"
                     /locus_tag="KOU88_002779"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBK3212647.1"
                     /translation="MNKVDKEKIQHAVREILEAIGEDPDREGLIETPNRVARMYEEIF
                     SGLSEEPRDHLKVLFADEKHEELVLVKDIPFYSCCEHHLVPFFGKAHIAYLPKGGRLT
                     GLSKLARVIDTLAKRPQLQERITKNAADIIMEELQPYGVLVVVEAEHMCMTMRGVKKP
                     GSKTVTSAVRGIFEKDIASRAEAMSLITMK"
     gene            complement(11049..11750)
                     /locus_tag="KOU88_002780"
     CDS             complement(11049..11750)
                     /locus_tag="KOU88_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212648.1"
                     /translation="MIGCIYEVYNEEITKIIENQNTLAVYLVGSSKDVDFTLYDVVIN
                     DIDVFVFVKEGEKQERILFKKKGIEFDVNYFSKDGVKKLLSNREYFFVKEMKDAKVLF
                     DRENISHIIKDISRDIYLEGPSKMSLEEKSFIKQDIGAKISNLKNKEKFDVFEYHFLT
                     NLYLKDIIIGYFNINDKWVPKDKKLLKVLKKENNELFELVSKVSENYDYQRLLDVYNY
                     IFKEIETKEVIKLIF"
     gene            complement(11784..12527)
                     /locus_tag="KOU88_002781"
     CDS             complement(11784..12527)
                     /locus_tag="KOU88_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV family protein"
                     /protein_id="HBK3212649.1"
                     /translation="MKNNVGFDSSLSKFGIGLFETIRVKNGIAVDLDIHIERMLSSIN
                     CLDLDINYKKDFLINEIVTYIKKENVINKALRITVFDEGYNISIRDISYNQETYEKGF
                     KLAISPIVRGNSLIHRHKTTNYFENIYTKNIANKTGYNDGIFLNSEDVILECSMSNIF
                     FIKGERVYTPSDRLPILNGIIKKRIIEICDELHIELIENEINISEISSFDFVFVTNSL
                     MGAIKVTEIDKIKFNKENVVFDKIVKLLE"
     gene            complement(12517..13866)
                     /gene="pabB"
                     /locus_tag="KOU88_002782"
     CDS             complement(12517..13866)
                     /gene="pabB"
                     /locus_tag="KOU88_002782"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HBK3212650.1"
                     /translation="MIREINTKLNSFEIFTIFRNEHDSFILDSAMDKEKLGRYSFISS
                     QPFKVLKYKDTDENPLEVLKEELHKYRVVNDTNLPFVGGAVGYLSYDLGNYIENLPRT
                     AVDDIEMPDMYFGFYNHVIVIDHLVQKTYIATPNIDIELEEKIIDDIEQRILKEEKKG
                     IDSICYEEKEVTPIRLKSNFTKEEFKNAVQSVREYIRQGDIYQANLTQRFSGETELTS
                     FELYRDLRRFSPAPFGAFLNFEDAHILSNSPERFIRCVNKRIETRPIKGTRPRGKDKE
                     EDLRLQQELRNSEKDRAELLMIVDLERNDIGRISKTGSVKVPELFVIEPYANVNHLVS
                     TVVGELKDDKDATDVIKATFPGGSITGAPKIRAMEIIDELEPTQRNVYTGSIGYIGFN
                     GDMDFNIAIRTIIKNDKKVYFQVGGGMTWDSDPDEEYQETLDKAKSIMKALRGYYEE"
     gene            complement(13868..14452)
                     /locus_tag="KOU88_002783"
     CDS             complement(13868..14452)
                     /locus_tag="KOU88_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HBK3212651.1"
                     /translation="MILMIDNYDSFVYNLVQYIEELGETVVVKRNNEIKISDIEELNP
                     EVIVLSPGPCSPKEAGICIDIVEHFKGKKPILGICLGHQTIGHVFGGDIIKAQQPVHG
                     KVYSINHTNKGVFRGLKNPLNVTRYHSLIVDSNTVPKELEITAITDKGEIMGIRHKKY
                     LIEGVQFHPEAILSEYGHEMLKNFITEARERVHM"
     gene            complement(14476..15195)
                     /locus_tag="KOU88_002784"
     CDS             complement(14476..15195)
                     /locus_tag="KOU88_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK3212652.1"
                     /translation="MTSWKKKTVYKCLIAVVLFCGIVLISNFSKVSALMMDTNGNVLI
                     KHGSREKKLIAITFDDGPHPKETSQVLDVLKKYNVKATFFIAGKHAKWYKEPLVRASK
                     EGHEIGNHTFNHPDISNLSSSQIEEEIVKCEDILKEVTGKKPTLFRPPFGSYREKELI
                     EIAKKHDYKVVLWTGVDVKDWKNPGANSIADKIINKVQNGDIILLHDYATNDTVEALD
                     MFIPKMIEKGFKFVTVSELIK"
     gene            complement(15223..16287)
                     /locus_tag="KOU88_002785"
     CDS             complement(15223..16287)
                     /locus_tag="KOU88_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBK3212653.1"
                     /translation="MKRLIALVLVVLIVLFYSPELLKEGYDLKEKFFQSEIWNEFLDK
                     ININDNSKKDKKEKSQNLQSNNTEGENLGESDIKNFEKISLGDNLSYVLSSIGKPGRI
                     DISEYGFDWYVYNQYGKEFAMVGLENDEVVALYSNSINSCENQDIKLNQDRQTVRTKI
                     TPLKYKRKGNTRYIINSENQYDIISKEGKYITIFYDIHEENRVCSYLIIDKSTEDEFK
                     NLYPDDSEELKKCFELEVIDLVNSVRNQRGLNSLRYSEQATLSSRKHSEDMRDNNFFD
                     HVNKKNETPFDRMKREGIVYTSAGENIAAGQINAIYAHEAWMNSEGHRKNILGNYNNI
                     GVGAIFGGSYKTYYTQNFYK"
     gene            complement(16431..17240)
                     /locus_tag="KOU88_002786"
     CDS             complement(16431..17240)
                     /locus_tag="KOU88_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212654.1"
                     /translation="MNLSKEYVNLYDNYLKYINEVNKEIRSIKNMKKRVLKRGDFAPE
                     NEVLELEGKTIRDIDDVDTKKPKNKIYKFSNGDVYVGKFLEGKMEGKGSYTFFVDEGT
                     VMEYIGEFKEDKKNGKGNFIFSNGNEYIGYFEEDMMSGIGNMLYSSKDEYIGTWKNGK
                     KDGKGIYKWSDGCIYAGEFKGGKMEGYGICYNSKGEVLYEGEWKNNLIHGKGTYIWEK
                     GKKYIGEFMHGKKHGQGTFYLNNELVYEGTWKFDKPSIFDRTLDEIFSLRL"
     gene            complement(17482..18348)
                     /locus_tag="KOU88_002787"
     CDS             complement(17482..18348)
                     /locus_tag="KOU88_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK3212655.1"
                     /translation="MSEVKNTLQKHPVLRYSTMLFGMLMTSIGINGFLRPAHLLSGGA
                     TGIATSINYLTNINVGLLTFLINIPIFILGFIYLEKEFCISSLVNMIVFSLLLGATQE
                     ISNIIPIHDILLQSVYGGILSGLGVGVVFRTRSSQGGTDIIAAILKIKKNIEMKDTAL
                     AINGLIVLTGSFLFGLDLALYTLIGLFLNAYSMSFIKDAMNYQKSVMVMSNEVDLIAE
                     DIMKSLVRGVTFLDAEGAYTHQKKKIIYTIVSSNEIPKIKDIALKYDKKAFISVNDVT
                     EVKGRGFKAKDL"
     gene            complement(18868..19557)
                     /locus_tag="KOU88_002788"
     CDS             complement(18868..19557)
                     /locus_tag="KOU88_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBK3212656.1"
                     /translation="MYNVLQTPVFGIIVTIVFFNLGRYIQRKTSNPICNPLLIAIVGI
                     ILFLSISKIPYENYKIGADSLNFFLGPVTVVLAVPLYKQFELFKKHMFEIIVGIGCGI
                     VISFVSVLIIGKIANSDVSIINSLIPKSITTPMGISLANSLNGIESITVVAIIFTGIF
                     GGMVASTVFKLGNINHPVAKGIALGTSAHALGTTKAFELGEIEGAMSGVSIGVSGTIT
                     VILIPIIMNFI"
     gene            complement(19550..19921)
                     /locus_tag="KOU88_002789"
     CDS             complement(19550..19921)
                     /locus_tag="KOU88_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBK3212657.1"
                     /translation="MKVFNQLVIILSIWVIGEYISSFIQGIILIPGSIVGMLLLFLLL
                     QFKVLDLSSIENVSGFFLDNMAIFFIPAGVSLIKSLDLIRENVLVLLLVICLSTLIVM
                     YTTGIIVEKMIKKKEEGQKNV"
     gene            complement(20103..21449)
                     /locus_tag="KOU88_002790"
     CDS             complement(20103..21449)
                     /locus_tag="KOU88_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK3212658.1"
                     /translation="MPRKILDISLIEDNKSDLTFFNIEEEDGDETLKALKQSYVTTNY
                     KEETLLNLQGALNSKSDTTSKELKLESYKRYNNALDLAYKNYITSAINMVNKALEINP
                     KDIDILNLRGLLKLLKCDFAKSFESFYTALCYENNHISRKYVNLISSEDFKTFLGRYN
                     HSIRFINEELNYESIHILENIIEEEPELIEPYVILSLLYDKLGNVKKREGYLDKLKEL
                     DKDNPVFEKNEEEKEDTSKKEEIKKVKRKKSILPYIIVGCVLIGMGIYLIQSKKRIEN
                     LNNQISSKEEKLSETDKKLGETSKKLEKTNKELNEVKNKEPEREITVADEEDLYYQAL
                     NLKKNKEYEKAIDNFKSVVSSGKTKKYISESIYQLAITNKLLGNKDEAIKYYKKYINT
                     YTKNDQYYDDSYYELGMLYYDNGDLKNAQQTFYSLRSEVPDSMYNNSKIKEILSEK"
     gene            complement(21631..22224)
                     /locus_tag="KOU88_002791"
     CDS             complement(21631..22224)
                     /locus_tag="KOU88_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HBK3212659.1"
                     /translation="MNLNNITNYVQSICENISNVLDVDVTLVTKDLTRIAGTGIFRGK
                     IGETISEKSVYSLVLKDGKSYVINKEIEENCNKCANRENCKELADICTPVKMGEHILG
                     ILGIAAFNEEQKEKILSKDKELTAFVRSMSDLISFKLDELYKQEVKTIDDLEREAIEN
                     AIKKYGSNTEGMKKVAEALNIGIATLYRKVKKFNIKS"
     gene            complement(22289..23743)
                     /locus_tag="KOU88_002792"
     CDS             complement(22289..23743)
                     /locus_tag="KOU88_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanW family protein"
                     /protein_id="HBK3212660.1"
                     /translation="MSNVNKKLVIAIGAVALVVIIFIGIMCMQFKGEKIAKNTYVNGV
                     NIGKLTKSQAKQELAKKYKLENVDFNYNDKSWKVKSKDLNLSTDLDKTVENAYNLNRK
                     SAFFGNLSKTISANFGKKSNLVVAINYDKNKLKAEMEKIAKEIDVDVKDATLDISGEK
                     VKVIPDSDGLKMDISKSMENFDNQTKKGNYKNELVVKATPAKVKKEQLANIDTNLGTY
                     STTFKTSQINRSINIKLATDNISNVLLMPGETFSFNKHTGKRSKENGYKSAPVIMEGE
                     MEEDYGGGVCQVSSTLYNSVLYAGLEIVNVKNHTIPSSYVPKGRDATVADSGIDFLFK
                     NNLKHPVYIKNYVSGNQIVCNIYGSAEDKQNITISTKLDGVSQTTMKRVNDPTMPKGK
                     EKVDKSGRNAYSVSTYRTFNDANGKKIKTEKIANSYYPKKEGIILVGTMEPKPEEKPN
                     TDENKNNQNPNNQQKPETPPTDNKPNETQPQPQA"
     gene            complement(23858..25249)
                     /locus_tag="KOU88_002793"
     CDS             complement(23858..25249)
                     /locus_tag="KOU88_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBK3212661.1"
                     /translation="MNFRDLFEKAVDFIDEKRKSIVAISLSTLGVIALIIVFFLSSNE
                     FSVGNEANELLKIIEKRQYSIAVDYYTSIEKKFSDSKMERFNKSVSKKINKLLLNSGD
                     KYLDGDISQESFIGLINTVKELNKISIDVDDLLAQADRVREMYKEENTTYDIAINYIS
                     TVSILNGMGSNLDVYKQNIETIKESRDVYDSAVKDQKAYKYYEAIEKYNKVLKEDEKY
                     YSMAQNGKEQCIEEMYDYYISRAEEANTSGDYERALQYIEYLKDDYSDDEKVQSLEKK
                     YKKNLSLYTLTSDDIINVIAKKSGKDKANLSINSLPQMIKNNKYYYAEVYEYDKLINE
                     VLVSAKTKDLYSYKDGKKDYKVDYGDGYFRILEDGSYQFGITKDKAKFVLTNTLDEKE
                     NKYKKIEILDIEKADRYVKSKKSLEELFGKYKNIYYYAVVNKGLFRGKEVYAINIYNE
                     KIYAISENGLNEY"
     gene            complement(25415..25663)
                     /locus_tag="KOU88_002794"
     CDS             complement(25415..25663)
                     /locus_tag="KOU88_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212662.1"
                     /translation="MMICFAMTFALVLINSVMGVHIGLDYYFLMGSVLTVCLTIGIVL
                     CNARKIFDSKAIHKTRTKTVSNNKKQKSHSRDIKRKIS"
     gene            25929..28058
                     /locus_tag="KOU88_002795"
     CDS             25929..28058
                     /locus_tag="KOU88_002795"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBK3212663.1"
                     /translation="MPNLPSLGSKAPDFKANTTNGPIRLSDYKGNWIVLFSHPGDFTP
                     VCTTEFLCFAKYYDEFKKRNTELIGLSVDSNSSHLAWMYNISLLTGVEIPFPIIEDRD
                     MRIAKLYGMISKPMSDTSTVRSVFIIDNNQILRTILYYPLTTGRNIPEILRIVDALQT
                     SDRDNIVTPANWFPGMPVILPYPKNYKELKNRVNSCNKKYSCMDWYLCFVPDNYNDEE
                     VSKKIDNTCSWKKEHTKNIENECNCEHEHHDYLNKALDCKQEHKTDIKDDCNHEKKHT
                     KNTNKVHNSKQDKFKDKSCDEMNFNYDKDESCDKINSSYNKEDSSYEDFYKHNYKNYD
                     YTSEKNTKKIAMKTLKDSKKLARPQITDPYNPIVENANCPDINPIVAEYVLGNPTNVD
                     AQLLDAVIFAFAEIDQSGNLFIPYPRFLNQLLALKGEKPSLKVIVAIGGWGAEGFSDA
                     ALTPTSRYNFARQVNQMINEYALDGIDIDWEYPGSSASGITSRPQDRENFTLLLTAIR
                     DVIGDDKWLSVAGTGDRGYINSSAEIDKIAPIIDYFNLMSYDFTAGETGPNGRKHQAN
                     LFDSDLSLPGYSVDAMVRNLENAGMPSEKILLGIPFYGRLGATITRTYDELRRDYINK
                     NGYEYRFDNTAQVPYLVKDGDFAMSYDDALSIFLKTQYVLRNCLGGVFSWTSTYDQAN
                     ILARTMSIGINDPEVLKEELEGIYGQF"
     gene            complement(28285..28884)
                     /locus_tag="KOU88_002796"
     CDS             complement(28285..28884)
                     /locus_tag="KOU88_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease H family protein"
                     /protein_id="HBK3212664.1"
                     /translation="MAKQKFYAVKKGKNIGVYNTWDECKKQVNGFSGAEYKSFSTFQE
                     AKEYIDGSEKLSFQEDKEFIEAYVDGSYEHSVKMYGSGVVILKNNEVIKTYSEKGKEK
                     TLVSMRNVAGEIEASKIAMQYCIDNNVQNLILYFDYEGIEKWCTGVWKTNKEGTIAYK
                     NFYDSIKNKLNVKFTKVKAHSGNKYNEEADKLAKKAIGV"
     gene            complement(28902..32021)
                     /locus_tag="KOU88_002797"
     CDS             complement(28902..32021)
                     /locus_tag="KOU88_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBK3212665.1"
                     /translation="MDNIISVLNDVVFLDIEVSGLDCLNSEILEVGAVKVKDWKIYTY
                     ESLIKNKFEVPIEVFSVCKNLDKNDLEIANKIELVEDRLVNFVEDSFIICHDLSLKKK
                     FFEYHMPKLKNKFIDLIELAVILEPYHKDYSLEYLKNTLTNCNSKVENRALSDAIDII
                     NIVNCLLVKFNNYEKTTLEPLSFKINSYLKKFNLPTWEWSKFLEEANYDLSNNINIKK
                     EYNIFDSKEEKKKERETLKILNEEEKNYEELLKYKTIWENKEGFTYEYRPGQYELTKT
                     IRELFRNSEDEEKIACIEAPTGIGKSVGYLLPAILEARINKKRLLISTDTKELQIQLI
                     NKDIPNVLDSLGLNGKVSYGYIKGKNNYICIDRLEAYIDDYESQNPTKGEILSLIFLK
                     RLVEGGKYGDIEEINYLVFDNFKEISTHLRNVSCDPNMCRPKKCKKDCLYKNRIEELK
                     EEHITVVNHSLLAKWPYKDEKPLENIIVDEAHNLTEKGYDFFSSIINSKSLRYLLQEI
                     YPYEFIQNSSFIYKKYSRNMRKIKAFDKFYNVLKIGREDKQKIARSINFIIEEIDSIL
                     KFGNCNEYNNVSNYNLRWELNLQIDEIVGKLKKDGIDTEISYRAYSEKIKLSCEKIIK
                     NLVSIIIIIYRNIDDDSIDKEADIYKFGKAKTRDLEDIKIIFEIFLEYDEKDDYARIV
                     EIDKNYNDFEFRVVPLKIADLFEENILSQLEKGIFLSATLSLSESMSYFKNTLGIDRV
                     KNVEKIIEPIFDYKNRVSVVGFSDICEYRNSEFPNEMSKIISNISKITEGHTLALFNS
                     KDRQEKTYEILKKYLHSFNLEIYADKKGIRHLNDLNRKCVVLGSKGCFEGVDIPGDGL
                     VCVTLDKLPNLNPKDPLYFTIMKKYGIDYYTINYPQMTIKVKQAMGRILRSKYDYGCF
                     VIFDVGTNISVLKRLEKDLHDCKISKVNSNEFYTYIRRHLNKSRSLILKSVIFDTIKA
                     LNVDAKMDNNDVDKDIIKKDINENIRQRAVKGEVYHIDIIKKDMKVKYFDRNYLINLD
                     IFMREEDKN"
     gene            32242..33066
                     /gene="pdaA"
                     /locus_tag="KOU88_002798"
     CDS             32242..33066
                     /gene="pdaA"
                     /locus_tag="KOU88_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lactam-biosynthetic de-N-acetylase"
                     /protein_id="HBK3212666.1"
                     /translation="MKKDSLKKYIMIGAFALILFGIASINFKSLDKTKTQISSPTLDT
                     HEYDWYFNPREDGKQPSPIKEADFFKKYGAYYVGNPNEKVIYLSFDAGYESGNTPKLL
                     DTLKKHNAKAQFFVVESYIKSNPELIKRMEKEGHLVCNHSKSHPSMAGITDFEKFKEE
                     ITSVEKAYKDVTGKEMPKYFRPPMGKFSEQSLKYTQDLGYKSIFWSFAYVDWYEKKQP
                     THEFAKNKIYSRTHPGAIVLLHPNSSTNTEILDEVLTHWEKEGYKLKTLDYLNNKK"
     gene            complement(33163..33948)
                     /locus_tag="KOU88_002799"
     CDS             complement(33163..33948)
                     /locus_tag="KOU88_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3212667.1"
                     /translation="MIVKIDNTLEKEFWQYVSHEESLNLFIIGYVENYGFSSQYQDIW
                     SQVEDGNITSIILKNKSTLIIYSFKNNFNIGEMKNHIKDLDVESISGKKCVIDRLISK
                     YKDFYEKLDNKFCVLKEIKEIDFSNMKEYKIENAQEKDIDEIGKLLNRSDYKVSKNYI
                     EERKVHLKEGNVRAYFIRNDDTMISTVSTGMETSFLAMVVSVSTDKRYRGKGLASYMV
                     YNLSKELLLEGKVPCLFYNNDVAGKIYHNIGYKEINEWTILFK"
     gene            34413..34778
                     /locus_tag="KOU88_002800"
     CDS             34413..34778
                     /locus_tag="KOU88_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212668.1"
                     /translation="MKIRAEYTCPLEIVHDIIKGKWKTILIFELRQSNKTFSELQHNI
                     YGINQKMLIQQLKELRDFGIIDKISSAGYPLHVEYFLTNRGKKMLKAVEIMQEIGIEY
                     MLEHGQQEILDNKGICYNK"
     gene            34856..35410
                     /locus_tag="KOU88_002801"
     CDS             34856..35410
                     /locus_tag="KOU88_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK3212669.1"
                     /translation="MSIALILIDIQNDYFKNGKCELFQSEETAENAKKILLFFRKNNL
                     PVIHIQHISTDKTASFFLPNTHGSEINKIVFPLDNEEIIIKHTPDSFFETDLQSILEK
                     KNITNLVICGMMSHMCIDTSVRTAKKLRYDITLISDACTTKNLSWNNIEINANTVHQV
                     FMASLQNSFADVKNTDKFLSNYHK"
     gene            35630..36304
                     /locus_tag="KOU88_002802"
     CDS             35630..36304
                     /locus_tag="KOU88_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBK3212670.1"
                     /translation="MNHHILIQFEYIARIITAGFCGALIGYERKNRLKEAGIRTHFIV
                     ALASALIIIVSKYGFNDIVGTPGIGLDPARVAAQVVSGIGFLGAGLIFIRNQSVSGLT
                     TAAGIWATAGTGLAIGSGLYLVGIVSSIIIVIVQITLHRDRKWMKLPTAEQVSLKISN
                     STDSIEYIEGKFKKSNIEIINMNIKRLDGDWLEVVIYTKLPKGYKKTNLLKLFSDNPL
                     IETLEI"
     regulatory      36659..36755
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
     gene            36809..36985
                     /locus_tag="KOU88_002803"
     CDS             36809..36985
                     /locus_tag="KOU88_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212671.1"
                     /translation="MFRDEMDKCTHMLTAYISSLYDYCDFIDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            complement(37172..37411)
                     /locus_tag="KOU88_002804"
     CDS             complement(37172..37411)
                     /locus_tag="KOU88_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212672.1"
                     /translation="MKCSNCGSVNIEKGILTTGGIYAETIGLKYRGDRKLDKVINKTF
                     PVQSTIYSDLCLDCGEIVRTYIKDNIDRNWCKDKK"
     gene            complement(37556..38365)
                     /locus_tag="KOU88_002805"
     CDS             complement(37556..38365)
                     /locus_tag="KOU88_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3212673.1"
                     /translation="MKDYYKIGEISKIYGIGRDSLMYYEEIGILRPVRDINGYRMYNI
                     SDIWKLNLIKEFRSLNFPMKKIKEYLDDRSIESTKNILNEELDLIDKKIAEFISHKEN
                     IIKRLSSIESVIQNTKIDEIEVVYIEKRKALELNADIKRDEDFDFLIQKLQKEYEDRF
                     NILGNNNIGSAFSTEAINKGIFNEFKSVFCFLESNEKVYNIVFDEGYYVTLNYTGSNS
                     NNKMYMEKVFKFIEENNYKIIADPIEIYKIDIHETGIVEEFVTEIQVPITK"
BASE COUNT        12476 a         6559 c         3957 g        15579 t
ORIGIN      
        1 tttttatagc atttaactat aatcaattgc cagactcaat tgccactcat tggaacataa
       61 atgggtctcc tgatgttttt atagataaat catttcttaa tgtatttaaa ttaatcggta
      121 ctgacttttg tttaatggtt ttattatata taacttccat tggatccata aagtcaagga
      181 ttaagataga tacaaataga attgaagaaa gtagagttga aaacattaaa tatttaaata
      241 aaattggtta tttgttttta atattgatga ttataatgac aacacagttt tttactactc
      301 ttttatcaat aaaaacaaaa ctatcaactg ctatgaatat tacaacgctt ttagttataa
      361 tttatttaat agcaacatat attaattccc caaatttaaa attcaactca tcttattctc
      421 cagaagaaga tgagaagtat tggatagcag gcatcatgta taataatcca aatgacccat
      481 cattaatggt taataaaagg tttggtattg gatggactat aaattttggc aatcctcttg
      541 gaaaaatact atatattgct atagctttac ttttaatttt ttcattgttt agcctaataa
      601 aatctctctt actttaaaat accataaaag gtatcttact tgtattattg ggtattatat
      661 tttgtaggat aagaaatatt tcatattatc gttgaagtat agtatttata tattactaag
      721 aatggagatt ttcataatgt tgtcaaaagc tgaaatcaaa tattttaatg aatgtgcttc
      781 tgagatactt tcttctgaaa aagttcaact tatgagaaca tttcctcatc atggcaatgt
      841 ttcatgtctt gaacatagtt tgtcagtagc atattatagt tatctattat gtaaaaaatt
      901 gcacttaagt gttgatattc aaagtgttat tagaggagct ttactacacg acttttttct
      961 ttatgattgg cattacaaag gtgatagaaa aggattacat ggatttactc accctagaga
     1021 agcattaaaa aatgcaactt tattttttca aataaatgaa aaagaaacgg acataatttt
     1081 aaaacacatg tggccactta ctgttaagcc acctagatac aaagaagcat ttattgtatg
     1141 tttgttggat aaattttgct gtttagttga gactttaaag atacattctt tattatctcc
     1201 ttaccatgta taggacaatt cccacaacac ttttataact taattttgaa gaggtattaa
     1261 gtattatatt caacttgata cctctttact atttattatt ttatataata atattttctt
     1321 tataatatcg ttgtaaacaa caacttctac cctcgataac ttccccttct tatagacctg
     1381 cttactacct taaataacaa gaaaccagct attaaattta ttagtattgt ttgtactact
     1441 ctaacaataa tatcataaat aaacctcaaa atagcttctc tttcactacc ttttatctta
     1501 aactatattt ttttcttaaa atttgtaaaa aacatagcat aatctttata aatgttctaa
     1561 aatttaattt aagcatcaaa attagaaagg atgatattat gtttaaagaa atgagattga
     1621 aaaaaagaga aatgacaaaa gaagatactg ttgaagtatt aaaaaatggt gaatttggta
     1681 ctttttccac tatatctgaa aatggttatc cttatggagt tgctgtaaat tatgtatact
     1741 ttaatgattc tatttacttt cattgtgcaa gaaatgggca taagttagat aatatatcga
     1801 aaaacaacaa agtttctttt ttagtagttg ctaatgaaag tgttattcca gataaattta
     1861 gtactactta ttctagtgct atagtttttg gaaaagcttg cactgtagaa aatgaagaaa
     1921 agaaaaatgc tcttgtagaa ataataaaaa aatattctaa aggattcttt gaagaaggca
     1981 tgaagtacat agagaaggat atgaacttaa caactgttgt taaaatagaa attgaccata
     2041 tttctggtaa agcttcacgt ttataattaa gtaaaaatac ctaaaagtat atacagtcgc
     2101 ttttaggtat ttttatatga tattcttata tgttaagtct ttttaggtaa tctcttatac
     2161 ctatcttggc atcatcattt ggtcttatat cagaattatc tcctgctata tgaagtattc
     2221 catacgctgg ataacctcct cttactgaac atggaactga caaaagagtc attcccatat
     2281 gttgggcaaa tatattcata gcttgcaaag ctaattctcc tcctccatgt tgtgaacctg
     2341 ctgtagcaaa acaaccaaat attttaccac tcaaaggagc acctacccaa atatcagaaa
     2401 aactatccat aaacatcttc attggtccag atacatttcc ataatatgtt ggtgaaccca
     2461 taaatatagc atcataatct aatatttctt ttccagattt aattacattt atactttcaa
     2521 attcgtcttt gtattctttg gaatttatca aataatattg aggaagtgtt tttgcaactt
     2581 cgtcacttac tctaaatata tctacctcga tattcatttc ttcaagcgct tctttatatt
     2641 ctctagctaa taaatatgta ctcccacaaa cactatgaaa aattactgct actttcatca
     2701 ttatccccct aattaaactc aaatttattt tttatatagt atttttatta tcaaacactg
     2761 ctaaatagta ctaaatggat tcaaatatac attactcttt attacttcaa tttcactaaa
     2821 ttcatctaaa aatctcttca taacattttt gaatatatct tctgtatcaa aatgaccaca
     2881 atccactata cacattccaa tatcaagtgc atcttgtgcc tcatgatact ttacatcacc
     2941 cgtaattagt acttctgcac cttgtctctt agcttttttt acaaattctg aaccagctcc
     3001 tgttacaacg gctactttcg ttatgtctgt actaaggttt ccaactactc ttatgtgttt
     3061 catatttaat ttctctttta ttttccttga aagactttct aatgtcatac ttttatcaaa
     3121 tttacttatt ctacctagtc caaatatctc acctttattt tctaacttgt acaaatcata
     3181 tgcaacttct tcataaggat gtgcatctaa catagaactt attaccccac ctaaaagctt
     3241 ctgtggtact acagtttcaa ttttaacttc atttacagtt tctatatcat ttacacttcc
     3301 aagaaacgga ttagagcctt ctaatggctt aaattgtcct tcaccttctg ttgaaaacgt
     3361 acaatcacta taattcccta tatgacctgc tcctgaatta cttaaaacct ttctaagttc
     3421 atctgaatag ttatgtggaa cgtatactgc taatttatac aaattttcgc ttttagttat
     3481 atctaaaacc tttgaattac caaattccat aatttccata aaatagtcat ttagaccatc
     3541 aaatgctata tcaaaattcg tatgcataga ataaagtgat atatcatttt taataagttt
     3601 ttggataagt ctgcctttta aatctccact attaatttta ttaattttcc caaatataaa
     3661 aggatgatgt gtcacaatta aatctatatt tttggatata gcttcatcaa taacatcttc
     3721 attagcttct aaagatacca ataccttttt tacatccata tcaaaatctc caactataag
     3781 acctacatta tcccaatcct ctgctaagtt tagaggatac tttttttcaa tttttctagt
     3841 tagactcttt aatagcatat atacctccta tttattttat taaattttca agttttttta
     3901 ttgcaacttc gctttccttt ctcttcttat ctatagcttc cccatttttc ccttctaatt
     3961 tattaactat agaactatat gtctttatct ttttttctat aaaatcatta aaaagagaat
     4021 ctttgttttc taaaagcttt attccaactt cataatatat ctcatcttct attatagtat
     4081 ttttacctgt atatttggca acaattatct catatattct aaaatcttct ctcactaaaa
     4141 cttcttctaa aatttcatat ccgttgttta aaaggtaata tctaagttct tcttgtgctt
     4201 gcattggctg taatattaat ttttctacat tatgtgctac ttctttttta gcctcgagaa
     4261 gctcacttat caagattcca cccataccag caattatcac ttcttctact tcccctattt
     4321 caagtatctc tataccagaa cctaatcgta aatcaacttt atctaaaaga ttgttctgta
     4381 tgacttcttt atgtgcattg tcaagaggtc ctttattaac atccgctagc actgcaaatg
     4441 gtacttttcc ctcttttaac aaatatactg gtatgtatcc gtggtccgtt cctatatcag
     4501 ctattttttt accatctgac actaatgatg ctattttcaa taatctatct gttaatttca
     4561 aatataattc tcctttcaat tccctttatt tataggattt aatccaagtt atagatatta
     4621 gactgaaata actacaaaaa taaaattaaa tctttactac aaaatagcca tgagatatca
     4681 cttatctcat ggcatttatc acaaaaacat caatgatgta tctttttagt ctaaataatc
     4741 tctaagtttt tttgatctac ttggatgtct tagttttctt agtgcttttg cttctatctg
     4801 tcttattctc tctctagtta catcaaactc ttttccaact tcctcaagag ttctggctct
     4861 accatcctca agaccaaatc taagctttaa tactttttgt tctctatcat ttaatgaacc
     4921 aagtacatct tctatttgtt cttttaataa agaatatgct gctgcctctg ctggggctgg
     4981 agcatcatca tctggaataa agtcacctaa atggctatct tcttcttctc ctattggtgt
     5041 ttctaaagac acagggtctt gagctatttt cattatttct cttactttat cttctgtcat
     5101 ttccatttct tttgcaattt cttctggttt tggatctctt ccaagttctt gaagtagttg
     5161 tcttgatact cttattagct tatttatagt ctctaccata tgaactggta ttcttatagt
     5221 tctagcttgg tctgcaatag cacgtgttat agcttgtctt atccaccatg ttgcataagt
     5281 actaaactta tatccttttg tatagtcaaa tttttcgact gcttttataa gacctaaatt
     5341 tccctcttgt attaaatcca agaaaagcat acctcttcct acatatcttt ttgctatact
     5401 tacaactagt cttaagtttg cttcaactaa cctttgtttt gctatctcat caccttcgtg
     5461 catccttcta gcaaattcta cttcttcatg tggtttaagt agaggaattt ttcctatttc
     5521 ttttaagtac attcttacag ggtcatctat acttatccct tttggtaaag ataaatccac
     5581 agtttctatt tctattgcag aagagtcatc atgtgaaatt gcctctgcat cttcatctaa
     5641 gtggcctata cttaaatcgt catcagcaac cgaaaaatct atatcagctt tatagttttt
     5701 tgtttctgtt atttctattc ccaaatttcc taaagtctca taaagatttt ctacttgatc
     5761 cttatcaagt tcagtctccg aaaaagcttc cattatctct gcaagtgtca aagaaccttg
     5821 cttttttcct ttttctatta atgtcttagc agtaaccttt tttaactctt ttttattcga
     5881 tttattttcc acactcaaac ctcctttctc tacaagctct ttaaaatttt atttatctca
     5941 actattttta aagcaatttc cataactcta ccatctacct ctttcatatc attattattt
     6001 tctaattctt gttgttctct caacaagcta ttaatttgct cttctaatga gttttttctg
     6061 atatttgtta ttattccttc tatttctttt gtgttctcta agtttatact attcaaagaa
     6121 attgaattta attcttttaa gtattcttcg gatatgttta aacttttcaa tttgtcaata
     6181 gttattttgt ccaattcttg atttttaatc atgtaattta aaatttcttt actttctttc
     6241 aataaaaaat cactttcttc tactttaagt aacgctattt ctctaatttt tttgtcttct
     6301 aacattattt ttattagagt ttcttcaact aattgttttc cgtcttgtct gacttcgact
     6361 ttttcaatta ctttttcttc tattttcttt tgatttttgt tattatatgg cttattgtaa
     6421 tttttaccat aaacttctct ctttatagac tcgacattaa tatctatttg attgcttaaa
     6481 tactttgtat aaaaatcaat ttcaacagga cttgtcaatt gttttataat tttagaagct
     6541 tcttttgcga acttcactcg ttcttcatct ttttgaatgt taaattcctt tttaagatga
     6601 tctattttat attttatgta gtgagtagaa acatccatag cttttttata atcactaagt
     6661 ccgtattttc ttacaaattc atctgggtct ttagcatctt ttaagtctaa cacttttaca
     6721 ttgataccta atttagtaag tatatctata gctcttaaag tcgcttttat tcctgcttca
     6781 tcagaatcat aagatataat agcagtgtcc gcatatctct ttattaaaat gccttgttgt
     6841 tcagtcaagg ctgttccaag ggttgctact acatttttta taccatactg ataaagtgaa
     6901 attaaatcca tatatccttc aactaagact atagttttac tttctaaatt ttttctagca
     6961 aaatttaatc cgtataagtt ctgtttttta ttaaaaatta atgtgtctgg agaatttaag
     7021 tattttggca aagaatcgtc taatactctt cccccaaatc ctattatatt tcctctataa
     7081 tcgaatatag gaaacataac tctatttcta aatttatcat agcaattagt tccatctcta
     7141 ttttttgcaa ttagaccgca ctccaataag tcttgttttt tatatccttt actgattaga
     7201 gtattcataa gtgaattcca tgaatccaaa gaaaatccta aaccaaattt cttaataatt
     7261 ttatcatcta gtcctcttat tcttaaatat tcatacccaa gatttttgct tcccaataag
     7321 tttgaaagat aaaatctagc tgcttccgta tgaatatctt gaaatttctt agatttttct
     7381 attttaatcc tagtttcttc attcatgtta gtgttaattt ctataccgca tttatttgct
     7441 aaaattttta cagcatccat aaaatccaaa ttttccattt tcatgacaaa atttattacg
     7501 tctccacctt caccacaacc aaaacactta taaatctgtt ttgacgtatt tatataaaaa
     7561 gaaggtgtct tttcgccatg aaatggacat aatcctttgt aattagctcc agattgtttt
     7621 atattcatat attcagatat tatacttgct atatcgcatc tagcttttat ttcttcaata
     7681 atgtctttta tatcattcat attatcacct tctggtgtaa ttttttgtgt taacatttct
     7741 attctacact atattctaaa tttgtcaatc actcaatata cacaattcga ctttttttat
     7801 tgatatcctt cttattaatc aaaaaatttt tattttttat attaattcta tcaatattaa
     7861 atctttattt atattaaata atctaactat caaattataa cttataaatt taccttagca
     7921 acgattacga ataaaaaaga ggctcttgcc tcttttaata attattaatt gatttcatta
     7981 aatcttcaaa ttcattaaag caaagagatt gagcaccatc tgacaaagca ttttctgggt
     8041 caggatgtac ttctaccatt attccatctg ctccacatgc aaaagatgcc agtgacatag
     8101 gttttaccaa atatctaact ccagtggcat ggcttgggtc taccacaaca ggaagacctg
     8161 tttccttttg aataatgggt actgcagcta aatctaatgt atttctagta taatcattat
     8221 acgttcttat acctctctca cacattataa tattactatt tccttctatt gctatatatt
     8281 cagaagcacc tatccattca gtaattgtgg atgctattcc tctttttaac ataacaggtt
     8341 tattttgttt tcccacttca cttaaaagag taaagttttg catatttctt gacccaattt
     8401 gaattatatc acttatacta tacagttcgt ccatatctct tacatccata agttctgtaa
     8461 taacagccat accaacttcg tctttaactg cttttaatat ttcaagacct tcttttttta
     8521 atccttgaaa tgaatttggc gatgttcttg gcttgtatgc tccacctctt aaaatatttg
     8581 ctccctgacg ttttacaaat ttagcagtct ccaaaagttg ctcataactc tctattgcgc
     8641 atggtccagc tattataagt ttatcttttt ttacagttat ctttttgtta tttgtattta
     8701 tctctatctt tgaattatta ttaaataggt tttctttcat aacctacaag ctcctttact
     8761 tcttctcttt cttcagcaga taggaggttt aaatgttctt ttattgtttt ttcatttatt
     8821 ataagttttt catttaaatc cataagtggt atcaaaacga aagctctatc ttgaatcctt
     8881 ggatgaggta ttgttagtct ttcatcagtg gaaactacat cattaaaaaa tagtacgtct
     8941 acatctatag ttcttggtcc ccaatgaact attctctctc tgtgtagttc tctctctatt
     9001 tcttgacaat attctaacaa ctcataaggt tcaaactctg tttctatttc tacacacata
     9061 tttagaaaat ctgcttgttc tgtatatccc catggttttg tttcgtataa gcttgattct
     9121 tttactttat atatagaatc actatttttc aaaagttcac atgctcttga taaattatca
     9181 aatctatcac ccatgttagt acctattccc aaataagcct tattcatctc ttgttctcct
     9241 tatctcaaca ccaaaatagt cataaatacc atttacagga gcctcaggct ttctaactct
     9301 gaccataact ccatttataa gtataaattt attcaagact tcttcagcaa tattttccgc
     9361 taaagcctcc aaaagattaa attgtttatt ttcagtaata tctttaacaa cattgtaaac
     9421 ctcggcatag cttacagatt tatttatatc gtcactaaga cctgcttctc ttgaatcaat
     9481 ataaagttcc atgtcgacaa agaatttctg acctagaaaa ttttcttctt taagaacacc
     9541 atgatatcca tagaatccta gattactaag taatatttta tccattatat tatacctact
     9601 ttctatatat tgcatcagtc attctagctg ccattaaatt ttcataaaca tcatgtactc
     9661 taactatatc tacgccatct cttataccaa gaacagtagt agctattgta ccttctaatc
     9721 tttttttagg ctcaactgga agtacttttc ctattactga ttttctggat gtcccaagca
     9781 aaataggata ccctaaatct tttaattcat ttaatcttct caatacttca atattttgtt
     9841 caaaatcctt gccaaatcct acacctgggt caagtactat tttttctttt tttacaccac
     9901 aactcattgc catttctata cttaccttaa aaaagtcttt tattgactcc attatatctt
     9961 tgtcatagtt tgtcccatct tgattatgca ttatacacac ttctgcatca tattttccta
    10021 ttacagaagc catattttta tcttttctaa gaccccaaac atcatttacc atagtgacac
    10081 ctaattttaa tgcttcttct gcaacatctg ccttataagt gtctattgat attggtatat
    10141 ccaattcctg tttaagtttt tttattacag ggattactct tcttagctct tcgtctgagt
    10201 ctacatagct atgacctggg cgtgtagact ctcctcctag gtctattata tctgcacctt
    10261 ggtcaaccat atcttttgca tgttgtattg ctatgtccaa gttattaaaa tctcctccat
    10321 cagaaaaact atctggagtt acatttaata ttcccattat ataagttctt ttaccataat
    10381 caaacacaat taatgacact cccttaaatt aaattttatc tcaataaatg attatatcta
    10441 taataaattg ctacttcata gtaatcaaac tcatagcctc ggctctagac gcaatgtcct
    10501 tttcaaatat tcctctcact gctgatgtaa cagtttttga acctggtttt tttacgcctc
    10561 tcattgtcat gcacatatgt tcagcttcta ctactactaa gacaccataa ggttgtaatt
    10621 cttccattat tatatctgca gcatttttag tgattctttc ttgtaattgt ggtctttttg
    10681 ccaatgtatc tattactcta gcaagtttag aaagccctgt aagtcttcct ccttttggta
    10741 aataagcaat atgagctttt ccaaagaaag gaactagatg atgctcacaa catgaataaa
    10801 atggaatatc ttttaccaat actaactctt catgtttttc atctgcaaaa agaactttta
    10861 aatggtctct tggttcttca ctaagaccag agaatatctc ttcatacatc ctagcaactc
    10921 tatttggagt ttcgattaga ccttctctat ctgggtcttc cccaattgcc tctagtattt
    10981 ctcttactgc atgttgtatc ttttctttat caactttatt catttaaact ccccccattg
    11041 atttgtgact agaagattag ttttataacc tcttttgtct caatttcttt aaaaatataa
    11101 ttataaacat ctaaaagtct ttgatagtca taattttcac ttacttttga cactagttca
    11161 aaaagctcat tattttcttt ttttaaaact tttagcaatt ttttgtcttt tggtacccat
    11221 ttatcattta tattaaagta cccaattatt atatctttta aatataaatt cgtcaaaaaa
    11281 tgatattcaa aaacatcaaa tttttcttta ttttttaaat tcgatatttt tgctccaata
    11341 tcttgcttta taaaagactt ttcctctaat gacattttac taggtccttc taagtaaata
    11401 tctctactta tatcttttat aatatgtgat atattctccc tatcaaacag tactttagca
    11461 tctttcattt ctttcacaaa gaaatattcc ctatttgata ataatttttt tacaccatct
    11521 tttgaaaagt aatttacatc aaattctatt cccttttttt taaacagtat tctctcttgt
    11581 ttttcccctt cttttacaaa aacgaacaca tcaatatcgt ttatcactac atcataaaga
    11641 gtaaaatcta cgtctttact agaacccact aaatatacag ccaaagtgtt ttggttttct
    11701 attattttag ttatctcttc attgtatact tcataaatac aacctatcat cttttgtctc
    11761 caacaaattg ttaatatttt aatttattct aataacttca ctattttatc aaaaacaaca
    11821 ttttctttat taaattttat tttgtcaatt tctgtaacct ttatagcgcc cataagacta
    11881 tttgtgacaa aaacaaaatc aaaactacta atttctgata tattaatttc attttctatc
    11941 aactctatat gtaattcgtc acaaatctct ataatccttt tttttattat tccatttaat
    12001 atcggtaatc tatcactagg agtgtacact ctttctcctt ttataaaaaa aatattgctc
    12061 atagaacatt ctaatattac atcttctgaa tttaaaaata taccatcatt ataaccagtc
    12121 ttatttgcga tatttttggt atatatgttt tcaaaataat tagtagtctt atgtctatga
    12181 attaaactat tccccctaac tattggagat atagctaatt taaacccctt ctcatacgtc
    12241 tcttgattat atgaaatatc cctaatagat atattataac cttcatcaaa aacagtaatt
    12301 ctaagtgctt tattaatgac attttctttt tttatatatg taacaatttc atttatcaag
    12361 aaatcttttt tatagtttat atctaaatcc aaacaattta ttgaacttag cattctttct
    12421 atatggatat ctaaatctac tgctattcca tttttaactc taatagtttc aaacaaacca
    12481 attccaaatt tacttaaact actatcaaaa cctacattat tcttcataat atcccctcaa
    12541 agccttcatt atggatttag ctttatcaag tgtttcttga tattcttcat ctgggtcaga
    12601 atcccaagtc attcctcctc caacttgaaa gtagactttt ttgtcatttt tgattattgt
    12661 tctaattgct atattaaaat ccatatcacc attaaaacct atataaccta ttgaaccagt
    12721 atatacattt ctttgcgttg gctctaattc gtctataatt tccattgctc taatcttagg
    12781 tgctcctgtt atagatcccc ctggaaaagt tgcttttatt acatcagtag catctttatc
    12841 atcttttaac tcacctacaa ctgtggaaac taagtgattt acatttgcat atggttcaat
    12901 tacaaatagc tctggaactt taacacttcc agttttagat attctgccaa tatcatttct
    12961 ttccaaatct actatcataa gtagttcagc tctatctttt tcactatttc taagttcttg
    13021 ttgaagtctt aaatcttctt ctttatcttt ccctcttgga cgagtacctt ttattggtct
    13081 agtttctatt ctcttattaa cacatcttat aaatctttct ggagaatttg ataatatatg
    13141 tgcatcttca aagtttaaga atgccccaaa tggtgctggg ctaaatcttc ttaagtccct
    13201 atacaattca aagcttgtaa gttctgtttc tccactgaac ctttgtgtta aattagcttg
    13261 atatatatct ccttgtctta tgtactctct aacactttga actgcatttt taaattcttc
    13321 ctttgtaaaa ttagatttaa gtcttatagg tgttacttct ttttcttcat aacatatgct
    13381 atctatacct tttttctctt cttttaatat tctttgttct atatcatcta ttatcttttc
    13441 ttctaattcg atatctatgt ttggagtagc tatataagtt ttttgcacaa gatggtctat
    13501 aactattaca tgattataaa atccaaaata catatcaggc atctcaatat catctacagc
    13561 agttctaggt aaattctcta tgtaattacc taaatcataa gataaatatc ccacagcacc
    13621 tcctacaaat ggaagattag tatcattcac aaccctatac ttatgtagtt cttcttttaa
    13681 aacttctaaa ggattttcat cagtatcttt atactttaat accttaaatg gttggctact
    13741 tataaaagaa tatcttccca atttttcttt atccatagca ctgtctaata taaaactgtc
    13801 atgttcattt ctaaaaatag taaatatctc aaaagaattt aatttagtat ttatctctct
    13861 tatcatatta catatgtacc ctttctctag cttctgttat aaaattttta agcatttcat
    13921 gaccatactc tgacaaaata gcttctggat gaaactgtac tccttctatt aaatatttct
    13981 tatgcctaat ccccattatt tcccctttat cagtaattgc tgtaatttct aattcttttg
    14041 gaactgtatt ggagtcaact attagtgaat gatacctagt gacatttaaa ggatttttaa
    14101 gtcccctaaa aactccttta ttagtatggt tgatactata tacttttcca tgcacaggct
    14161 gttgtgcttt tataatatct cctccaaaaa catgtccaat agtttggtga cctaaacaaa
    14221 ttcctagtat aggttttttc cccttaaaat gctcaacaat atctatgcaa ataccagctt
    14281 cttttggaga acacggtcct ggagataaca caattacctc tggatttagt tcttcaatgt
    14341 cacttatttt gatttcatta tttcttttta ctacaactgt ttcccctaat tcttctatat
    14401 attggactag gttgtataca aaagaatcat aattgtctat cataagaatc atactgtaaa
    14461 tctcccccct aaaaattatt ttatcaactc agaaactgtt acaaatttaa aacctttttc
    14521 aatcattttt ggaataaaca tatctaaagc ttcaactgta tcattagttg cataatcatg
    14581 caaaagtatt atatctccat tttgtacttt attaattatt ttatctgcaa tgctattagc
    14641 tcctggattt ttccaatctt tcacatctac acctgtccat aaaacaactt tatagtcatg
    14701 cttcttcgca atttctatta attctttttc tctataactt ccaaatggtg gtctaaataa
    14761 tgtcggtttt tttccagtta cttctttcaa aatgtcttca cacttaacaa tctcctcttc
    14821 tatctgacta gaacttaaat tacttatatc aggatgattg aaagtatgat ttcctatctc
    14881 gtgaccttct ttacttgctc ttactaatgg ttctttatac cattttgcat gttttccagc
    14941 tataaaaaaa gtagctttta cattgtattt ctttaataca tctaaaactt gactagtttc
    15001 tttaggatga ggaccatcat caaaggtaat tgctattagc tttttttccc ttgaaccatg
    15061 tttaatcaaa acatttccat tagtatccat catcaaagca gaaactttac taaaattaga
    15121 tattaacact attccacaaa acaagactac tgctattaag cacttatata ctgtcttttt
    15181 tttccatgat gtcatttttt aacttccttt caaatatttt agttatttat aaaaattttg
    15241 agtgtaatat gttttatagc ttcctccaaa tattgctcca actccaatat tattatagtt
    15301 ccccaaaata ttttttctat gtccttcaga gttcatccaa gcttcatgcg catatattgc
    15361 attaatctgt cctgctgcta tgttttctcc agctgaagta tatactatac cttctctttt
    15421 cattctgtca aatggagttt cattcttctt atttacatgg tcaaaaaaat tattatctct
    15481 catatcttca ctatgttttc ttgaactcaa agttgcctgt tcactgtatc tcaatgagtt
    15541 taaccctctt tgatttctaa cactatttac aaggtctata acttcaagtt caaaacattt
    15601 tttaagttct tcgctatcat ctggatataa atttttaaac tcatcttcag tgcttttatc
    15661 aattattaag tatgaacaaa ctctattttc ttcatgaata tcgtagaaaa ttgtaatata
    15721 cttaccttcc ttacttatta tatcatattg attttctgag tttattatat atctggtatt
    15781 tccttttctc ttatatttta atggtgtaat cttagttctc actgtttgtc tatcttgatt
    15841 tagttttata tcttgatttt cacatgaatt aatagaatta ctataaagtg ctactacttc
    15901 atcattttca agtccaacca ttgcaaattc ttttccatat tgattatata cataccaatc
    15961 aaaaccatat tcactaatat caattctacc aggtttacca atacttgata aaacatagct
    16021 taaattatct cctaagctta ttttttcaaa attctttata tctgactctc ctaagttctc
    16081 cccttcagta ttatttgatt gtaaattttg acttttttct tttttatctt tcttagaatt
    16141 atcatttata tttattttgt ctaaaaattc attccatatt tcactttgaa aaaacttttc
    16201 ttttaaatca tatccttctt ttaataattc aggactataa aataaaacaa taagtactac
    16261 taacactaaa gcaattaatc tcttcaatat atctctcctt cttaaaatca atcaaaattt
    16321 tttaatattg catttattaa attaatattg atagtgtata ctaatcaata tcattcatac
    16381 ctatttacag taagtattag aaaaaagctt tatctactaa ttagataaag ctacagtctc
    16441 aaggaaaata tttcatctaa tgttctatca aatatagatg gcttatcaaa tttccaagtc
    16501 ccttcataaa ccaattcatt atttagataa aaagttcctt gcccatgttt tttaccatgc
    16561 ataaattcac ctatatactt tttacctttt tcccatatat aagttccctt accatgaatc
    16621 aaattattct tccattctcc ttcataaagt acttcccctt tactattata gcaaataccg
    16681 tacccttcca tctttccacc tttaaattca cctgcatata tacatccatc actccactta
    16741 taaatacctt ttccatcttt ttttccgttt ttccaagttc caatatattc atctttacta
    16801 ctatataaca tatttccaat accgctcatc atatcttcct caaaataacc tatatattca
    16861 tttccatttg aaaatataaa gtttcctttt ccattttttt tatcttcttt aaattctcct
    16921 atgtactcca taactgttcc ttcatctaca aaaaaagtat atgagccttt cccctccatc
    16981 tttccctcta agaattttcc tacatataca tccccatttg aaaatttata gattttattt
    17041 tttggttttt ttgtatcgac atcatctata tcgcgtattg tttttccttc caattctaat
    17101 acttcatttt ccggagcaaa atcgcccctt tttaaaacac gtttcttcat gttctttata
    17161 cttctaatct ctttgtttac ttcatttata tatttcaaat aattatcata caaattaaca
    17221 tattctttag ataaattcat aatgccattc ctccaacgtt attcctagat attttactaa
    17281 atctattaaa tttattatat cctaatagtg gtcatgtttt ctacatatta agtaattttt
    17341 tcaattttaa ttttaaaatg atatctttta aagtgataca caaatcatta ataaaacctt
    17401 tattttcgta tactaaattt aaataagctg agagatataa tatacaaatt tacattataa
    17461 actcccagct tgtaaaattt tctataaatc ttttgcttta aaccctcttc cttttacttc
    17521 tgtaacatca tttacagata taaaggcctt tttatcatac ttcaaagcta tatcttttat
    17581 ctttggtatc tcatttgatg aaactattgt atatataatc ttcttttttt gatgagtgta
    17641 tgcaccttct gcatctaaaa aagttacacc tctaactaaa ctcttcatta tatcttctgc
    17701 tattaaatcg acttcatttg acattaccat aacagatttt tggtaattca ttgcatcttt
    17761 aataaaactc attgaatacg catttagaaa tagacctata agagtgtata atgctaaatc
    17821 caacccaaat aaaaaacttc ctgtaagtac tatcaagcca tttattgcta aagcagtgtc
    17881 tttcatttct atattcttct taatttttag tattgcagct attatatctg taccaccttg
    17941 agaagaccta gttctaaata caactccgac tcctaaacca gataatatac caccatatac
    18001 actttgaagc aatatatcat gtataggtat aatattactt atttcctgag ttgctcctaa
    18061 taataatgaa aatacaatca tatttaccaa acttgaaata caaaactctt tttcaaggta
    18121 tatgaaccct aagataaata ttggaatatt gattaaaaat gttaataaac ctacatttat
    18181 atttgtcaaa tagtttatag atgttgctat acctgtagca cctccactaa gtagatgtgc
    18241 tggtcttaag aacccattta ttcctataga tgtcatcaac atcccaaata gcattgttga
    18301 atatcttaaa actggatgtt tttgtagggt attcttaact tcactcattt ctttctccct
    18361 tcaatctttc taaatcttta gaattttaaa agcttactct tacatatatt attcctgatg
    18421 taatagataa tatttcaaat aaattttttt tataatttct tgaactgtca tctattacat
    18481 catctattat attatctttt tcatatatgt ctagtgcaat cttttatatt ctaatcttta
    18541 aaaacgttca aatcatctca tttatgcctt aaatgaaact ttttctagca taatatgata
    18601 ctgcttatta tttaacttgc aatatagtaa atttatagta tttttttcta aatatctatt
    18661 ttcgcagtaa tttattttat tttagcaaat tcaagtttag taattgtctc tttataatta
    18721 attcctaaat gaaatttttc tttttataat ttcagtacat gattttttta tttcattatt
    18781 tgcatttttt tcattcagtt tttattttaa atttttttta ttttattttg ttttaagtat
    18841 tcaaggtact cgtcttaatt ttatttttta tataaaattc attataattg gaattagtat
    18901 tactgtaatt gtaccagaga ctccaataga aacaccactc atagctcctt ctatttctcc
    18961 cagttcaaaa gcctttgtag ttcctaaagc atgtgcagat gttccaagag caattccttt
    19021 agcaactgga tgatttatat tccccagttt gaatactgta gaagcaacca taccaccaaa
    19081 aatacctgta aaaattatgg ctacaactgt tattgattct ataccattta aagaatttgc
    19141 taaagatatt cccattggtg ttgttataga ttttggaatt agtgaattta ttatacttac
    19201 atctgaatta gctattttgc caattatcaa tacagataca aaagaaatca ctataccaca
    19261 acctattcct acaataatct caaacatatg ctttttaaat aattcaaatt gtttataaag
    19321 tggaactgca agtactactg tgacaggacc taaaaagaaa tttagactat cagctcctat
    19381 cttgtaattc tcataaggga ttttagatat gcttaaaaac aatattattc ctacgattgc
    19441 aattaataaa gggttacata taggattact tgtttttcgt tgaatgtatc ttcctaaatt
    19501 gaaaaaaact attgttacta ttataccaaa tactggtgtc tgtaatacat tatacatttt
    19561 tttgtccttc ttccttcttt tttatcattt tctccacaat aattccagta gtatacatta
    19621 ctattagtgt acttaaacat atgactaata aaagcactaa tacattttcc cttattaggt
    19681 ctaatgactt tataagtgat acacctgctg gaataaaaaa tatagccata ttatcgagga
    19741 aaaatccact tacattttct atactactca agtctaaaac tttaaattgt agtagtagaa
    19801 ataataatag cataccaact atactcccag gaataagtat aattccttgt ataaaggaac
    19861 ttatatactc tcctattacc cagatagata aaattattac caattgattg aaaactttca
    19921 ttttccacct ccaaaaatta aagagattgc ttcaaatcat atatttgtag ttttatcaac
    19981 aagcaaatat ctttctttaa aatagaaagt tataatttga cacaatctct ttttaaattt
    20041 atttttattt taatttaata aaatacatac ttggttgttt caaaaaactt aactatataa
    20101 acctattttt cacttaaaat ttcttttatt tttgaattgt tatacatact gtctggaact
    20161 tcacttctca aactataaaa agtctgttgt gcatttttta aatcgccatt atcataataa
    20221 agcataccca actcgtaata tgaatcatca taatactggt catttttagt ataagtattt
    20281 atatattttt tgtaatattt tatagcttca tccttatttc ctaataattt atttgttatt
    20341 gctaattgat atattgactc agaaatatat tttttagttt taccagaaga aactacactt
    20401 ttaaaattat ctatggcttt ttcatattct ttgtttttct ttaaatttag agcttgataa
    20461 tataaatctt cctcatcagc tacagttatc tctctttctg gttctttatt tttaacctca
    20521 tttaattcct tattcgtttt ttctaatttt ttactcgttt ctcctaactt tttatcagtt
    20581 tcacttaact tttcctcttt actacttatt tggttattca agttttctat tctctttttg
    20641 ctttgaatca aatatatccc catacctatt aaaacacagc caactataat atatggcaaa
    20701 atacttttct ttctttttac tttttttatt tcttcctttt tacttgtatc ttctttttct
    20761 tcttcatttt tttcaaatac aggattatct ttatctagct ctttaagttt gtctaaatat
    20821 ccttctctct tttttacatt acctagttta tcatataaca aagataaaat tacatatggc
    20881 tctattagtt caggttcttc ttcaattatg ttctctaaaa tatgtattga ctcataattt
    20941 aattcttcat ttataaatct tatagaatga ttgtatcttc ctaaaaaagt tttaaaatct
    21001 tcagatgaaa ttagatttac atattttcta gatatatgat tattttcata acataaagca
    21061 gtataaaaac tctcaaatga tttagcaaaa tcacatttta ataattttaa aagacctcta
    21121 agatttagta tatcaatgtc tttaggattt atctccagag ctttattaac catattaatg
    21181 gcactagtta tataattttt atatgctaaa tccaatgcat tgttatatct tttatatgat
    21241 tctaatttta actccttaga cgttgtatct gactttgaat ttaaagctcc ttgcaagttt
    21301 aatagagttt cttctttata atttgtagtc acataactct gttttaatgc ttttaatgtt
    21361 tcatcaccgt cttcttcttc tatattaaaa aaagtcaaat cacttttatt atcttctatc
    21421 aaagatatat ctaaaatttt tctaggcatg ctttctatgt cttgttttat atctttaact
    21481 aaaataatac tcacctccac tctaaaatat atatttaaga taacatattt aatatgtcaa
    21541 gtcaaaacta tacatatttt tccaccattc tcataataaa aaaggtaatc ctcttctttt
    21601 cataaaaagg ttacctcttt ttcaatacta ttaactttta atgttgaatt tttttacttt
    21661 tctatagagt gtagctatac ctatatttaa tgcctcagct acttttttca taccttctgt
    21721 attacttcca tatttcttta tggcattttc tatagcttcc ctctcaaggt catctatagt
    21781 cttaacttct tgtttataaa gttcatctag tttaaaagat attaaatcag acatactcct
    21841 tacaaaagca gttaactcct tatcttttga aagtatcttt tctttttgtt cttcattaaa
    21901 cgcagctata cccaagattc caagtatatg ctctcccatt ttaacgggag tacatatatc
    21961 agctaactct ttacaatttt ctctatttgc acatttatta cagttctctt ctatttcttt
    22021 atttataaca taggattttc catcttttaa aacaagagag tacactgact tctctgatat
    22081 tgtctctcct attttacctc tgaatattcc tgtacctgct atcctagtta aatcttttgt
    22141 aactaaagta acatctacat ccaagacatt agaaatattc tcgcaaatac tttgaacgta
    22201 attcgttata ttatttaaat tcaaagtaat ccctcctatt tagatttata ttttttatta
    22261 ctctacataa atcctattct tgagaacttt aagcttgcgg ttgtggttgt gtctcattag
    22321 gcttattatc agttggtggt gtttctggtt tttgttgatt atttggattt tgattattct
    22381 tattttcgtc tgtatttggt ttttcctctg gttttggttc catagtccca actaatataa
    22441 taccttcctt cttaggataa tatgaattag ctattttttc agttttaatt tttttaccat
    22501 ttgcatcatt aaatgttcta tatgttgata cagaatatgc atttcttcca cttttgtcta
    22561 ctttttcttt acctttaggc attgtagggt cattaactct tttcattgta gtttgtgaaa
    22621 cgccatctaa ttttgttgat attgttatat tttgtttatc ttctgcactt ccatatatat
    22681 tgcaaacaat ttgatttcct gaaacgtaat tttttatgta aactggatgc tttagattat
    22741 ttttaaataa gaaatctatt ccactatctg caacagttgc atctcttcct tttggaacat
    22801 aacttgatgg tatagtatga ttttttacat taacaatttc taaacctgcg tataacacag
    22861 aattgtataa cgtagatgaa acttgacaaa ctcctccacc ataatcttct tccatctcac
    22921 cttccattat tacaggtgca cttttatatc cattttcctt acttcttttc cctgtatgtt
    22981 tattaaatga gaaagtttct cctggcataa gtaatacatt acttatatta tctgttgcta
    23041 attttatgtt tatacttcta tttatttgag aagttttaaa tgttgttgaa tacgtaccta
    23101 aatttgtatc tatattagca agttgctctt tttttacttt tgctggagta gcttttacta
    23161 ctaactcatt tttatagtta ccttttttag tttgattatc aaaattctcc atactcttag
    23221 aaatatccat tttaagacca tcagaatctg gtataacctt gactttttca ccacttatat
    23281 caagtgtagc atcttttacg tctacatcta tttctttagc tatcttttcc atttctgctt
    23341 ttaatttatt tttatcataa tttatcgcaa ctactaagtt gctttttttg ccaaaatttg
    23401 ctgaaatagt ttttgataga ttgccaaaga aagcactctt tctatttaaa ttatatgcgt
    23461 tttctactgt tttatccagg tcagtagata aatttaaatc tttgctcttt actttccaac
    23521 ttttatcatt gtaattaaaa tcaacattct ctaatttgta ttttttagct aattcctgtt
    23581 ttgcttgcga tttagttaat tttccaatat ttactccatt aacatatgtg ttttttgcta
    23641 ttttctcccc tttaaattgc atgcacatta tgcctataaa aattattact actaatgcta
    23701 cagctccaat agctataact agctttttgt tcacattact catcccatac ttctccttac
    23761 aataaaatta tttatatatc cctattatta tattactaca taatgcgcct taaaacccca
    23821 aaaacttttt aattatatat taatttaata ttattaatta atattcattt agtccatttt
    23881 ctgatatggc atatattttt tcattgtaaa tattaatagc ataaacttct ttgcctctaa
    23941 ataagccttt atttactaca gcataataat aaatattttt atattttcca aacaattctt
    24001 ctaaactctt tttacttttt acatatctat ctgctttctc tatatctaat atctcaatct
    24061 ttttatactt attttctttt tcatcaagag tattagttaa cacaaactta gctttatctt
    24121 ttgtaatacc aaattgataa cttccatctt ctaatattct aaagtatcca tcaccataat
    24181 ctactttgta atctttttta ccatctttat atgaatataa atctttagtt tttgcactta
    24241 ccaaaacttc atttattaat ttatcatact catatacttc agcataatag tatttattat
    24301 tttttatcat ttgtggaagt gaatttatag atagatttgc cttgtctttg ccactttttt
    24361 tagctattac atttataatg tcatcagatg ttaaagtata caatgataaa ttctttttat
    24421 attttttttc taaactctgt accttttcat catctgaata atcgtctttt aaatactcaa
    24481 tatattgtaa tgctctttca taatctccag aagtatttgc ctcttcagct ctacttatat
    24541 agtaatcata catttcttca atacattgtt ctttcccatt ttgagccata ctgtaatact
    24601 tttcatcttc ttttaatact ttattatact tttcaatagc ttcataatac ttatatgctt
    24661 tttggtcttt tactgctgag tcataaacat ctctagactc tttgattgtt tctatattct
    24721 gtttgtatac atctaggtta ctacccatac catttaatat tgaaacagta cttatgtagt
    24781 taatggcaat atcataagta gtattttctt ctttatacat ttctctaact ctatcagctt
    24841 gagctaataa gtcatccaca tctatactta ttttgtttaa ttctttcacg gtatttatta
    24901 atccaataaa actttcttga cttatgtctc catctaaata tttatcacca ctatttaata
    24961 gcaatttatt tattttttta gaaacagact tattaaacct ttccattttt gaatcagaaa
    25021 actttttttc tatacttgtg tagtaatcaa cagctataga atactgtctt ttctctataa
    25081 tctttaacaa ctcattagct tcatttccta cactaaactc gttactactt aagaaaaata
    25141 ctattatcaa agcaattaca cctaatgttg ataatgaaat cgcaactata gatttccttt
    25201 tttcatcaat aaaatctaca gccttctcaa ataaatctct aaaattcatt atagttccct
    25261 ctccatttaa taatctttat attttatggt aaactaaatt tcttattggt tattatatca
    25321 taattcttga aaaaaaataa aaacacaagt taaatcgtgt ttttatttta cctatcaatc
    25381 attattttat acataaatat ttcctttaca taaattatga tatctttctt tttatatccc
    25441 tagaatgact cttttgtttt ttattattac tgacagtttt cgttcttgtc ttgtgtatag
    25501 ctttgctatc aaatattttt ctagcattgc ataaaacaat tccaattgtt aaacaaactg
    25561 taagcacact tcccatcaaa aagtaataat ccaatcctat atgtactccc ataactgaat
    25621 ttattaacac taatgcaaaa gtcattgcaa aacatatcat catggagata actaaaattc
    25681 ttagaatttt tttcaatcca ctcacctcgt ataatcacta aaattgacac taccccttat
    25741 ccattactat accaaattag taaaaaaata gcaattacta ttgtcattta tattaggaaa
    25801 atattaaatc tttttaataa atatcttttt ttgacataag gattacttaa cttttaataa
    25861 aatagtaaca ctaatatgta ttaattaata gaataaaata aatgataatt tattgagggg
    25921 tgatttacat gccaaatttg ccaagtttag ggtcaaaggc tcctgatttt aaagccaata
    25981 caacaaatgg tcctattaga ctctctgact ataagggtaa ttggattgtt ttattttcac
    26041 atcctggtga ttttacacca gtttgtacta cagaattttt atgttttgct aaatattatg
    26101 acgaatttaa aaaaagaaat acagaactaa ttggtctaag tgttgatagt aacagttcac
    26161 atttagcttg gatgtataat atttctttac ttacaggtgt agaaattcca tttcctatta
    26221 tagaagatag agatatgaga attgccaagt tatacggcat gatatcaaaa ccaatgagtg
    26281 atacatcaac tgttcgctct gtatttatta tagataataa tcaaattcta agaacgattc
    26341 tttattatcc actaactaca ggaagaaata ttccagaaat acttagaata gtagatgcac
    26401 ttcagactag tgatagagat aatatagtta ctcctgcaaa ctggtttcct ggaatgccag
    26461 tgattttacc ttatcctaaa aactataagg aattaaaaaa tagagttaac agttgtaata
    26521 agaaatattc atgtatggac tggtacttat gttttgtacc agataattat aatgatgaag
    26581 aagtgagcaa gaaaattgat aatacttgta gctggaaaaa agaacatact aaaaacattg
    26641 aaaatgaatg taactgtgaa catgaacatc atgactacct gaacaaagct cttgactgta
    26701 aacaagaaca caagactgat attaaagatg attgcaacca tgagaaaaaa catactaaaa
    26761 atactaacaa agttcacaac tccaaacaag ataagtttaa agataagtct tgtgatgaaa
    26821 tgaattttaa ctatgataaa gatgaatctt gtgacaaaat aaattctagc tataacaaag
    26881 aagatagtag ttatgaagat ttctataaac ataattataa aaactacgat tatactagtg
    26941 aaaaaaatac taaaaaaata gctatgaaga ctttaaaaga ttcaaaaaaa ctagctagac
    27001 cacaaataac agacccatac aatccaatag ttgaaaatgc aaactgtcca gatataaatc
    27061 caattgtagc agaatatgtt cttggaaatc caactaatgt agatgctcaa ctattagatg
    27121 cagttatatt tgcttttgct gagatagacc aatctggaaa tttgtttatt ccttatccta
    27181 gatttttaaa tcaattactt gctcttaaag gtgaaaaacc tagcttaaaa gtaattgtag
    27241 ctattggagg ttggggagct gaaggattct ctgatgcagc attaacacct acatccagat
    27301 ataattttgc aagacaggtc aatcagatga taaatgaata tgctttagat ggaatagata
    27361 tagactggga atatcctgga agtagtgcat ctggaataac atcaagacct caagatagag
    27421 aaaattttac actcttacta actgccataa gagatgttat aggagatgat aaatggctta
    27481 gtgtagctgg aacaggagat agaggatata taaattcaag tgctgaaata gataaaatag
    27541 ctcctataat agattatttt aatcttatga gttatgattt tacagcaggt gaaacaggcc
    27601 caaatggtag aaaacatcaa gcaaatcttt ttgattcaga cttatctttg ccaggatata
    27661 gtgttgatgc aatggtgaga aatcttgaga atgctggaat gccttctgaa aaaatccttc
    27721 ttggtatacc attttatgga agattaggtg ctactataac aagaacttat gatgagctta
    27781 gaagggatta tataaataaa aatggatatg aatatagatt tgataatact gctcaagttc
    27841 cgtatttagt taaggatgga gattttgcaa tgtcatatga tgatgcttta tcaatattct
    27901 taaaaactca atatgttctt agaaattgtc taggtggtgt attctcatgg acatcaactt
    27961 atgaccaagc aaatatactg gctagaacca tgtctattgg tataaatgac cctgaagtat
    28021 taaaagaaga acttgaaggt atttatgggc aattctaata gaatgtagta aaattttata
    28081 gttatataaa aagcagattt tattatatta aataagttgt atctaattaa tactattatt
    28141 aattgtttat aaattagata cttatttttt cataatacaa tctgcttttt taatcaaaat
    28201 ttatttaatt acaagttgtt taattataaa gtaggaattt agatatactc ttataccatg
    28261 taattatgta taaatatttt tttattatac accaatagct tttttagcta atttatcagc
    28321 ttcctcatta tacttatttc cagaatgagc tttaaccttt gtaaatttta cattaagctt
    28381 attcttaata ctgtcataga aatttttata tgctatagtt ccttctttat ttgttttcca
    28441 aactccagta caccactttt caatcccttc atagtcaaag tataaaatca agttttgaac
    28501 attattgtca atacagtact gcattgcaat tttagaagcc tctatctctc cagctacatt
    28561 tctcatactt actaaagttt tctcttttcc tttttcacta taagttttta taacttcatt
    28621 attttttaaa atcacaacac ccgaaccata catttttact gaatgttcat aacttccatc
    28681 tacatatgct tctataaact ccttatcttc ttgaaaactc aatttttctg acccatcaat
    28741 atattcttta gcttcttgaa aagtagaaaa actcttatat tcagctcctg agaatccatt
    28801 tacttgtttt ttgcactcat cccatgtatt atatacacct atatttttac cttttttcac
    28861 agcataaaac ttttgttttg ccaaatatat cactcccact cttaattttt atcttcttct
    28921 ctcataaata tatctaaatt tataagatag tttctatcaa aatattttac tttcatatct
    28981 ttttttataa tatcaatatg gtacacttct ccttttacag ctctttgtct tatattttca
    29041 tttatatctt tttttataat atccttatca acatcattgt tatccatttt agcatcaaca
    29101 ttcaacgctt ttatagtatc aaatataaca gattttagta ttaaacttct agatttattt
    29161 aaatgtcgcc ttatataagt ataaaactca ttgctattaa cctttgaaat tttacaatcg
    29221 tgtaaatctt tctctaatct ctttaacaca cttatattag ttcctacatc aaaaatcaca
    29281 aaacatccat agtcatattt gcttcttaaa attctcccca tagcttgctt tacctttatg
    29341 gtcatttgag gataatttat agtatagtag tctataccat acttcttcat tatagtaaaa
    29401 tacaaagggt ctttaggatt tagattcgga agcttgtcta aagttacaca aaccaaacca
    29461 tcccctggaa tgtctacgcc ttcaaaacat ccttttgagc caagtactac acattttcta
    29521 tttaaatcgt taaggtgtct aatgcccttt ttatcagcat aaatttctaa gttaaaacta
    29581 tgtaagtatt ttttcaatat ttcataagtt ttttcttgtc tatctttact attaaaaaga
    29641 gctaatgtat gaccttctgt aatctttgat atattagata taattttact catctcattt
    29701 ggaaattcag aatttctgta ctcacaaata tcagaaaatc caactacaga gactctattt
    29761 ttataatcaa aaattggttc tataatcttt tccacattct taactctgtc tattcctaat
    29821 gtatttttaa aataagacat actttcagat aaactcaaag ttgctgataa aaatattcct
    29881 ttttctaatt gagataaaat attttcttca aataaatctg ctatttttaa tggtactact
    29941 cgaaattcaa agtcattata attcttatca atttcaacta tccttgcata atcatccttt
    30001 tcatcatact ctaaaaagat ttcaaatata atctttatat cctctaaatc tcttgtcttt
    30061 gcctttccaa atttatatat atctgcttct ttatctatac tatcatcatc aatattccta
    30121 taaattatta ttattattga aactaaattt tttattattt tctcacaact caactttatc
    30181 ttttcactat aggctctata acttatttca gtatctatac catctttttt tagttttccc
    30241 acaatttcat ctatttgcaa attcagttcc catcttaaat tataattact tacattatta
    30301 tattcattac aattaccaaa ctttaatatt gaatctatct cttcaataat gaaatttata
    30361 cttctagcaa ttttttgttt atcttctctt ccaattttta atacattata aaatttatca
    30421 aaagccttta tttttctcat atttctacta tattttttat atataaagct actattttga
    30481 ataaactcgt aaggataaat ttcttgtaat aagtacctta aagactttga atttataata
    30541 cttgaaaaga aatcatatcc tttttcagtc aaattatgtg cttcatctac tattatattt
    30601 tctaaaggtt tttcatcctt atacggccat ttagctaata gtgaatgatt tactactgtt
    30661 atatgttctt cttttaattc ttctattctg tttttatata aacaatcttt tttgcatttt
    30721 ttaggtctgc acatatttgg gtcacaactt acatttctta agtgagtact tatttccttg
    30781 aagttgtcaa acactaaata atttatttct tctatatctc catacttgcc accttcaact
    30841 aatctcttca aaaatattaa agataaaatt tctcctttag tagggttttg agactcataa
    30901 tcatctatat atgcttccag tctatctata caaatatagt tattttttcc ctttatatat
    30961 ccgtaactta cttttccatt tagacccaaa gaatctaaca catttggaat atctttattt
    31021 attaattgta tctgcaattc ctttgtgtca gtagaaatta ataatctttt tttattaatt
    31081 ctagcctcta atattgcagg caataaatat cctacacttt tacctatacc agttggtgcc
    31141 tctatacatg caattttttc ttcatcttcg ctatttctaa acaactctct tattgtttta
    31201 gtaagctcat attgaccagg tctatattca tatgtaaatc cttctttatt ctcccaaata
    31261 gttttgtatt ttaataattc ttcataattt ttttcttctt catttaaaat ttttaaggtt
    31321 tctctttcct tcttcttttc ttcttttgag tcaaatatat tatattcttt ttttatattt
    31381 atattatttg ataaatcata atttgcctct tctaaaaatt tgctccattc ccatgttgga
    31441 agattaaatt ttttaagata tgaatttatt ttaaaactca atggctccaa agtagttttt
    31501 tcatagttat taaattttac taaaaggcaa tttacaatat ttattatatc aatagcatct
    31561 gataaagctc tattttccac tttagaatta caatttgtta aagtattttt taagtattct
    31621 aagctataat ctttatgata tggttctaaa ataactgcta attcaattaa atcaataaat
    31681 ttatttttta actttggcat atgatactca aaaaactttt ttttcagact taaatcatga
    31741 catataatga aactatcttc tacaaaattt acaagtctat cttccaccag ttctatttta
    31801 ttagctattt ctaaatcatt tttatctaaa tttttacata ctgagaatac ttctataggt
    31861 acctcaaatt tgttttttat taatgattca taggtatata ttttccagtc tttaaccttg
    31921 acagctccaa cttctaaaat ttctgaattt aaacaatcta atccactaac ttctatatct
    31981 aaaaaaacaa catcattcaa tacacttatt atattatcca tttttatatc ccttcaagtt
    32041 aaaccagcct aacttattta caatcatttc tctttatatt ttatcattta tatacacttt
    32101 atttaagata attaatatca actttatatc ttacagtaaa cttctttcat ttattatttg
    32161 tatatgtgaa tatttttaac tataaatatt caaactatat tataagaaat atactttaaa
    32221 ttttaaataa gaggtgaaat tgtgaaaaaa gatagcctaa aaaaatacat tatgatagga
    32281 gcatttgctc taatactttt tggaattgct agtataaatt ttaaatcatt agataaaaca
    32341 aaaactcaaa tttctagtcc aacactcgac acacatgaat atgattggta ttttaaccct
    32401 agggaagatg gtaaacagcc atcacctata aaagaagctg atttttttaa aaaatacgga
    32461 gcttattatg taggaaatcc caatgaaaaa gttatatatc tatcatttga tgctggatat
    32521 gaaagtggaa acactccaaa attattagat acgcttaaaa aacacaatgc taaagctcaa
    32581 tttttcgtag ttgaaagtta tataaaaagc aatccagagt taataaagcg tatggaaaaa
    32641 gaaggacatt tagtttgtaa tcattcaaaa agccatccat caatggcagg tattacagat
    32701 tttgaaaaat tcaaagaaga aattacaagt gtagaaaaag catacaaaga tgttactgga
    32761 aaagaaatgc ctaagtattt tagacctcca atgggtaaat ttagcgaaca atctttaaaa
    32821 tatacacaag atttaggata taaatcaata ttttggagtt ttgcttatgt agattggtat
    32881 gaaaagaaac aacctactca tgaatttgcc aaaaacaaaa tttattcaag aactcatcct
    32941 ggtgcaatag ttttactgca tccaaattca tcaacaaata ctgagatatt agatgaggtt
    33001 cttacacatt gggaaaaaga aggttataaa cttaaaacac ttgattattt aaataataaa
    33061 aaatagtatc ataaatttaa aaaaactcta tcatgaatta tagtaaaaat atagttattt
    33121 ataaatactt taattctcga tagagttttt tattttttat agctatttaa aaagaattgt
    33181 ccattcattt atctctttgt atcctatatt atgatatatt ttacctgcta catcattatt
    33241 ataaaaaaga catggaactt ttccttctaa caacaattct ttactcaaat tgtaaaccat
    33301 ataacttgca agtccttttc ccctatatct tttatctgta cttacagaga ccaccattgc
    33361 caaaaaacta gtttccatac cagttgacac agtgctaatc atagtatcat catttctaat
    33421 aaaatatgct cttacatttc cctcttttaa atgaactttt ctttcttcta tgtaattttt
    33481 acttacttta tagtctgacc tatttaaaag ttttcctatt tcatcaatat ctttttcctg
    33541 agcattttct attttatact ccttcatgtt ggaaaaatct atttctttta tttcttttaa
    33601 tacacaaaat ttattatcta gtttttcata aaaatctttg tatttactta ttagtctatc
    33661 tattacacat ttttttccac ttatgctttc tacatctaaa tcttttatat gattcttcat
    33721 ttctcctata ttaaaattat ttttaaaact ataaattata agtgttgact tattttttaa
    33781 tattatagag gttatatttc catcttctac ctgagaccat atatcttgat attgagagct
    33841 aaatccataa ttctcaacgt atccaattat gaataaattt aaactttctt catgtgatac
    33901 atattgccaa aattcttttt ctaaagtatt atctattttt acaatcaagc agatatcctc
    33961 cttctatgtt aataatgata taccttataa tttatagtat catttaaaat cattatattc
    34021 taccaaatat tctaaatttt taaatatcta tgcaatatgt tcgtatttat ttttatattc
    34081 tgttactgct tcactccaag cttcttctac tgaaatacct ctcttatttg caattttttg
    34141 tgctaattct attattttca tagcttttct tgatatattc atatatattc ctcctctaaa
    34201 ttatcataag ttattttaaa gttaaatttc tatagtcatg ttatatattt atttacttat
    34261 atcttactaa ttatttatgt actaaatatg aactacaata gaagaaattt agaacttaat
    34321 aaaacataaa atttatatac agttcatata tatttgtcat atcacaagac aagtgatata
    34381 atttattatc attttactgg gggtgatatg ctatgaaaat aagagctgaa tatacatgtc
    34441 ctcttgaaat tgtacatgac ataatcaaag gaaaatggaa aactatcctt atatttgaat
    34501 taagacaatc taataaaaca ttttctgaat tgcaacataa tatttatgga ataaatcaaa
    34561 aaatgttgat tcaacaatta aaagagttac gtgattttgg gattattgat aaaataagtt
    34621 ctgctggata tccattacat gttgaatatt ttcttactaa tcgtggtaaa aaaatgttaa
    34681 aagcagtgga aataatgcaa gaaataggaa tcgaatatat gcttgaacat ggtcaacaag
    34741 aaattctaga taataaagga atttgctaca ataagtaatc ctatacatac caaaaagtaa
    34801 gtaatttaca ttttttacaa tagtattata ataaaaataa ataggaggta taatcatgtc
    34861 tatagcttta atattgattg atattcaaaa tgattatttt aaaaatggaa aatgtgaatt
    34921 atttcaatca gaagaaactg ctgaaaatgc taaaaaaata ctactgtttt ttagaaaaaa
    34981 caatttacca gttattcata tacagcatat atcaacagat aaaacagctt ctttttttct
    35041 tcctaatact catggttcag aaataaataa aattgttttt ccactagata atgaagaaat
    35101 tataattaaa cacacaccag atagtttctt tgaaacagat ttgcaaagta tccttgagaa
    35161 aaaaaatatt actaatctag taatctgtgg aatgatgagc catatgtgta ttgatacaag
    35221 tgtaagaaca gcaaagaaac ttcgatacga cataactcta ataagcgatg catgtacaac
    35281 gaagaattta tcttggaata atatagaaat taatgcaaat actgtacatc aagtattcat
    35341 ggcatcacta cagaacagtt ttgcagatgt aaaaaacaca gataaatttt tatctaacta
    35401 tcacaaataa aaacatacac tatgttaaaa gagcaagttt gatttattta agcttgctct
    35461 ttaatcattt aaaattagat gctttctatc atttttatat acataatata cgtttataca
    35521 ttttatattc atatataact attatataaa ttttaaactt tactatattc acataaaaaa
    35581 tgtagtatta tagtatatat aatattatat agaagggggt gctagataaa tgaaccatca
    35641 tatattgatt caatttgaat atatagcaag aatcattact gctggtttct gtggggcttt
    35701 aattggatat gagagaaaga atagactaaa agaagctgga atacgcactc attttatagt
    35761 ggcattagct tcagcactta taatcattgt ttccaagtat ggatttaatg atatagtggg
    35821 tactccaggt attggtctag acccagcccg cgttgcagca caagttgtca gtggtatagg
    35881 ttttttaggt gctggattaa tatttattag aaatcaatca gtaagtggtc ttactacagc
    35941 tgctggtata tgggcaacag ccggtacagg tcttgccatt ggctctggat tatacttagt
    36001 tggtattgtt tcaagtatca ttattgttat tgtacagata acacttcata gagataggaa
    36061 atggatgaaa ctccctacag cagagcaagt ttctcttaaa atttctaaca gcactgattc
    36121 catagaatat attgaaggta aatttaaaaa atctaatatt gaaattataa acatgaatat
    36181 taaacgcctt gatggggatt ggttagaagt agttatatat actaagttac ctaaaggata
    36241 taaaaaaaca aatttattaa aattatttag cgataatcct cttatagaaa ctttagaaat
    36301 ataatataaa aattgaagct taaaaataat aatatattta atcaaggtca atatataaat
    36361 aattacggga tgagtctata taaaattcat cccttgtttt ttgccattca tatatatttt
    36421 ttcaagatat ttttgttcat ctattatcta gccaagtagc tcttgtgaac taaacttttt
    36481 aatacaaaaa cttcaataca aaactaaata taacttttat taaacattct acatatatag
    36541 tttgtttctt gagtgaaaaa tagatttcat attgttaaga tactgttaaa tatttcaatt
    36601 ttctgacaag tatgttgaac aataacttat cctagtgtat tattttagtt gtagaataaa
    36661 actaaatcgg caaaactaga gaaatttagt gacgcaaagc tatagggact aacgcttata
    36721 aaataaacta tgagttatgt cagccagttg ccaaaaagat attgttcttt ttgttttatg
    36781 aaagtttttt agggggatag taatatatat gtttagagat gaaatggata aatgtacaca
    36841 catgttaact gcttatatta gtagtttata tgattattgt gattttatag atacacagct
    36901 agatgatttt atactagagt acggagaaaa tgtagtagaa tcttgtttac atcaagtgat
    36961 ggtattggta agtaagtata attaaataga aattgttttc tagagaaccc tttttagttt
    37021 tatctacatt taaaaatgtt attatattaa aaaactaatc tcccctatat gcaaagtttc
    37081 ttccatataa caatttcttc ccatttatac tttttcactt atatctttaa taaaattcaa
    37141 cttcaaatat taatatactt caaaaattat tctatttctt atctttacac caattcctat
    37201 caatattatc ctttatatag gttctaacta tttcgccaca atctaaacat aaatctgaat
    37261 atatagtaga ttgtactgga aaagttttat ttataacttt atctaatttt ctatctcctc
    37321 tatattttaa cccaatagtt tcagcatata tgccaccagt tgttaaaatt cccttttcaa
    37381 tatttacact tccacaatta gaacatttca catttataac cccctaaaca attatttttt
    37441 catgctatct tataatttaa aatataattt gctaccgatt ttataacaca gtgacaaatc
    37501 ggtggcaaat caacattttt tcattctatt taccatctaa tccattgaaa tatagctatt
    37561 tagttatagg aacttgaatt tccgttacaa actcctctac aattccagtc tcatgtatat
    37621 ctatcttgta aatttctata gggtcagcaa ttatcttata attgttttct tctataaatt
    37681 taaacacctt ctccatatac atcttattat tagaattact cccagtataa tttaaagtta
    37741 cataatatcc ttcatcaaaa actatattat atactttctc attactttcc agaaaacaaa
    37801 atacagattt aaactcatta aatatacctt tattaattgc ttcagtagaa aaggcagaac
    37861 caatattgtt atttccaagt atattaaatc tatcttcata ttctttctga agtttttgaa
    37921 ttaaaaaatc gaagtcttca tccctcttta tatcagcatt taattctaaa gcttttcttt
    37981 tttctatata tacaacctct atctcatcta tttttgtatt ttgaattaca ctttcaattg
    38041 aactcaatct ttttataata ttttccttat ggcttataaa ttcagctatt tttttatcaa
    38101 ttaaatcgag ttcttcattt aaaatatttt tcgtagactc tatacttctg tcatctaggt
    38161 attcttttat tttcttcatt ggaaagttca agcttctaaa ttcttttatt aaatttaatt
    38221 tccatatatc tgatatatta tacattctat atccatttat atctctaact ggtcttagaa
    38281 tgcctatttc ttcataatac attaatgaat ctctacctat tccatatatt ttagatatct
    38341 ctcctatttt atagtaatct ttcatttata taataaactc ctccgaaatc ctatttttat
    38401 tttaaatcaa cattattact ctataatact atagtattag aatatactaa aaaaatcttt
    38461 aaaacaagga taggaaaata aacatcctaa taattaatta ttaaaatatt tttatattgt
    38521 aatattaggt atagtattta taacttcaac ttttttataa atatatttta g
//
LOCUS       DAFAZV010000041        37137 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFAZV010000041 DAFAZV010000000
VERSION     DAFAZV010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37137
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.041"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(86..490)
                     /locus_tag="KOU88_002806"
     CDS             complement(86..490)
                     /locus_tag="KOU88_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HBK3212674.1"
                     /translation="MKKYKVIFIVLIIGIISVTGFVVYKNCIKPWKDAETYIDKYMVK
                     QDISKDNIKSITKEKAKKASYEGILYKVYYKDDPRYEYQYFYSDNYYALYVNKVMLQI
                     YDMENNNKLLRSNEELKSVKYPPIYLKYKPDK"
     gene            complement(682..1869)
                     /locus_tag="KOU88_002807"
     CDS             complement(682..1869)
                     /locus_tag="KOU88_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBK3212675.1"
                     /translation="MSKIVFFSIPAYGHTNPTIEVVRELVDRGNEVLYYSFNEFKDKI
                     EGAGAKFICCDKYLPELLPGDEKKIGKDFPGLIEMIVDTTISLDEKVCRELKDFNPDC
                     IVSDSLSFWGKLFAQKLNIPYVCSTTTFAFNKHTAKLMKQNFIEIIRMIFGVRRINKK
                     IKLLQRKGYEVKNFISIVSNDNDTDTIVYTSKEFQPMVETFSSKYSFVGPSVSKLIIE
                     PKERKRKLIYISLGTINNKNVSFYKNCISAFKDSDVDVIMSVGRSTDIKSLGNIPNNF
                     EVKNSVEQIAILQKTDVFVTHSGMNSVNESLYYGVPMVLFPQHSEQRMVAKRVVHLGA
                     GIMLKEDKSESIKKAVFQVINDNEYKENATKLSKSFYNAGGSKKAADVILQIICNSRQ
                     VDI"
     gene            complement(1901..2326)
                     /locus_tag="KOU88_002808"
     CDS             complement(1901..2326)
                     /locus_tag="KOU88_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212676.1"
                     /translation="MINENLKSLRKINQYTQEELAEKLNVSRQSIAKWESGESIPDIC
                     SCIKLAKLYNVKLDDLVNHSEEKTGIIVPPKGKFFFGAVVVGERGQIVIPKEAREVFN
                     INAGDKLLVLGDEERGLGIVHQRDLINFIGHVGVVRKEE"
     gene            2804..3553
                     /locus_tag="KOU88_002809"
     CDS             2804..3553
                     /locus_tag="KOU88_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440038.1"
                     /note="N-terminal region resembles flavodoxins. C-terminal
                     ferrodoxin region binds two 4Fe-4S clusters; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EFR1 family ferrodoxin"
                     /protein_id="HBK3212677.1"
                     /translation="MILYFSGTGNSRYVARKIAQELNDELISLNQLIKEEKTDELISA
                     DKPFIFVCPTYAWRLPIVVTDFIKETKFLGSNRVYFVMTCGGDTAKSINYIQKLCKYK
                     EWQLKGMAEIKMPENYIALFSTTDKETSKQMIKEADKQIYRIISDIRNENEFETITPS
                     GLGGTIKSGIINTVFYKTIISAKGFHYTDKCIGCGKCVELCPLNNINLKNKKPVWKNN
                     CTHCMACICGCPTEAIEYKNKTQNRERYYLE"
     gene            complement(3719..4084)
                     /locus_tag="KOU88_002810"
     CDS             complement(3719..4084)
                     /locus_tag="KOU88_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK3212678.1"
                     /translation="MEKECQQRMQEITSKFKECRKAISAMGDETRQLILIALLESDFN
                     GIRVGEITKKTHLSRPAVSHHLKILKEAEIVNLRREGTKNYYYLDSKKSQWKSLTELI
                     NLIFVGIQHISENDIRKGD"
     gene            complement(4100..4876)
                     /locus_tag="KOU88_002811"
     CDS             complement(4100..4876)
                     /locus_tag="KOU88_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK3212679.1"
                     /translation="MKYQHIIEVDKELCIGCGLCKNDCPVNNIIIENKKSVIKKQDCL
                     MCGHCAAICPTKAITLTGFDEPPIELTNKPKLDSDELLMAIKSRRSIRKFKDKEVSSE
                     IIKQIIEAGRYTPSAKNSQDVSYIVLDNKKSIYENEAVKFFRKIKPIANIAIKYSKEV
                     EIDDNFFFKHAPIAIMIITKDKISGSLAASNMALMAESYGLGVLFSGYFSDVANNSPK
                     LKKLLGLKRSNHVLTTLVIGYPDVKYRRTAQKEVATVRYL"
     gene            complement(5287..6714)
                     /gene="ascB"
                     /locus_tag="KOU88_002812"
     CDS             complement(5287..6714)
                     /gene="ascB"
                     /locus_tag="KOU88_002812"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK3212680.1"
                     /translation="MSFKNDFLWGGATAANQCEGGYNEDERGLANVDVCPTGKDRTAV
                     ITGKLKMFDFDDEHYYPAKTGIDMYHNYKEDIKLFAEMGFKVYRMSIAWSRIFPKGDE
                     ETPNEKGLQFYENIFKECKKYKIEPLVTITHFDCPMHLVKKYGAWRNRKMIGFYEKLC
                     NVIFRRYKGLVKYWLTFNEINMILHAPFMGAGICFEEGEDVEKIKYQAAHHELVASAI
                     ATKIAHEVDSNNLIGCMFAAGSVYPYSCNPNDVWEATKLDRENYFFVDVQSKGKYPNY
                     ALKYMEQKGITPEMEPGDIELLNKYTVDFISFSYYNSRCVRTDENADDMAEGNIFTSA
                     KNPYLSYSQWGWPIDPLGLRITLNHVYDRYEKPLFIVENGLGAKDIADENGYVEDDYR
                     IDYLREHIKAMHDAVSIDGVDLLGYTTWAPIDLVSAGTGEMEKRYGFIYVDRDNSGNG
                     SLRRMKKKSFEWYKKVIASNGEDLY"
     gene            complement(6775..8703)
                     /locus_tag="KOU88_002813"
     CDS             complement(6775..8703)
                     /locus_tag="KOU88_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3212681.1"
                     /translation="MGKYKQLAQEIVNNVGGKENISGLVHCITRLRFTLKDESIANDN
                     VLKNMEGIVTVMKSGGQYQVVIGNHVEAVYKDVVEIIGLDDSSTSSETKKSGNILDKG
                     IDIISGIFQPVLGIMAACGMLKGFNALFVAMGLYSDVSGGYMVINAAGDALFTFLPLF
                     LGYTSAKKFGLKPMLGLALGAAVCYPAIQGSSISAGADVMYTLFKGTMFASPVYIDFF
                     GLPIVSIDYTGTVVPIIFIVYFASRCEKLFNKCVPDLVKFFFVPMLTLLITVPVALIV
                     IGPIATFGSTLISQIVISIRDFSPLLAGAIVGFTWQILVIFGMHWGFIPVYINNVMTL
                     GYDNVMMPFFACTFASSAVVLAIFFKTKDKKLKEMAIPNFISGIFGVTEPAIYGILLP
                     LKKPFIISCIASGIGGAFYGFFNLRKFITGGMGIFELPAMIEPDGGMGNLIVALSGIA
                     ISMVVAFVLTMILYKDEKVEESKKVRNKGKEEIKEVKSTKLEREIVTSPIKGEVLKLS
                     DIEDAAFASGVLGQGVAIIPSDGKVVAPVDGVVTTLFPSLHAIGILSDTGVEVLIHIG
                     LNTIQLEGRGFEACIKQGDRITKGQTILNFDVYAIKELGYSTVTPIVITNSSQFLDVV
                     ETESKNIELEDNLITVLF"
     gene            complement(8848..9690)
                     /locus_tag="KOU88_002814"
     CDS             complement(8848..9690)
                     /locus_tag="KOU88_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK3212682.1"
                     /translation="MIINKILNNNVVITLDDNDEEVIVMGKGIGYQKSKGNLIDKTKV
                     NKVFRISNKEISNKLQELLNNIPIEHMKLSSEIIEYAQIKLNKKLNESIYISLSDHTY
                     SAIQRMKEGINVKNAILWEIKRFYKEEFEIGMKALDIIENKTGIKLPEDEAGFIAFHI
                     VNAQLSEGHTLASDITKLIQEVLSIVRYHFRIEFHEESVFYYRFIMHLKFFAQRLLLD
                     SAHEGETDKELLSIIKSKYNKEFECVVKIKNFIKKQYNYILTDDELIYLTIHLAKVVK
                     DSNM"
     gene            complement(10037..11401)
                     /locus_tag="KOU88_002815"
     CDS             complement(10037..11401)
                     /locus_tag="KOU88_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK3212683.1"
                     /translation="MKNKYEEVAQLIIDGLGGKDNIIDLTHCMTRLRFILKDEKKVNA
                     DKLKSIDKVVGVNSTSTQYQVIIGNEVGVVFNAIINKGINTTGDIKSDIKNKKNSILN
                     NIIDTITGCMTPMIPALTASGMIKVILSLCTTFNWLSSNSSTYRVLDIIGDVAFYFMP
                     IILAINAAKKFNVNTSIAVIVVGVFLHPNFSAWVSSGDPISFIGVPIQGVIYVASVIP
                     ALLTVWMMSYIEKFIDKLTPSMLKTILNPTLVLLISAPIALIVIGPIGNFLGEGLASV
                     INLLQGRLGFIMVCLLAAAMPFIVMTGMHHALTPIFISAFATTGQESLILISQVCANL
                     AQGGATLAVALRSKDSKMKQLASAAWISAIMGITEPALYGVTLKLKKPAMLASIGAGI
                     AGLFAGITHVTLYVPQNSIMAVLGLSGEKGISNIVNGLIVIFIALVAPFIMTYVFGVE
                     KNVK"
     gene            complement(11440..12111)
                     /gene="pgmB"
                     /locus_tag="KOU88_002816"
     CDS             complement(11440..12111)
                     /gene="pgmB"
                     /locus_tag="KOU88_002816"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBK3212684.1"
                     /translation="MKAVLFDLDGVITDTAKYHFEAWHEIAKSLDIEIDETFNEKLKG
                     ISREESLDKILLSANKVDSYTKEEKLKVCEEKNNIYIKLINSLTYKDILPGINELIKE
                     LKKNNVKLGIASASKNAPRILESLGIKDEFDCIVNPSLLKRGKPYPDIFIEGSKILNL
                     KQYDCVGIEDSYSGIKAINAANMTSIGVGKKEVLGKCDHIVEDTSLLNCNTLLQAWSK
                     KINLD"
     gene            complement(12113..14503)
                     /locus_tag="KOU88_002817"
     CDS             complement(12113..14503)
                     /locus_tag="KOU88_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBK3212685.1"
                     /translation="MSLIFTTKDQLIEQGFSKDTIKSNETLFTLANGHLGVRGNIEES
                     DFNNEYVDNMGTYVNGFYEESPITYGESAYGYAKQNQTICKLPNAHIVNFSIEGDYFD
                     LSKGITSEHSRILDLNEGILKRSFIWENSCGRKVKVSIERLVSQDIEELMMISYTITP
                     LNFNGKIKFKNKMENSMEKFNCEKVDDPRVASINKKQFKINVKKYNNKYFMNLVTERS
                     RLGLWCGFDSYITCGNITNETYNVSDECIEREIEVYAKKDERLNLEIVVGYSRVYSDL
                     NLNEERLKSLECLESLKCLESEAHLKSLELVLREACNIGFDKVKNIQRKKMNEFWTTS
                     DVEIEGDKTLQLGIKTNLFHIYQSAGRDGKTNISAKGLTGDGYEGHYFWDTEMYILPF
                     FIYTQPSIARALLDYRYSILDASRERARELGINKGCLYSWRTINGNECSAYYPTGTAQ
                     FHINADIAYGIRTYFEATNDEEFMMQNGLEILIETARFWVEFGDYIESKNNKFCINGV
                     TGPDEYTAIVNNNYYTNLMAKYNLIYAVQMVDKFKHNLFSNEVFRKVKLQEYEVKNWI
                     NAAQNMYLPYDEEKKISKQDDSFLEKSVWDFKNTPKEKYPLLLHYHPLTIYRYQVNKQ
                     ADTVLSALLFPDEFSLEQKKRDFEYYEKITTHDSSLSRSIFGMMASEIGNHEKAYNYF
                     MDTALMDINNLQKNTSDGIHAANMGGTWMSLVYGFAGMKIKNDKLSFEPRIPKHWKNI
                     KFNILFRDNLVSVNIEEYKSYYKLIKGRNITILHDNKEIKLSKNIIEVNNCFKGSN"
     gene            complement(14529..15977)
                     /locus_tag="KOU88_002818"
     CDS             complement(14529..15977)
                     /locus_tag="KOU88_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBK3212686.1"
                     /translation="MKLGKDFLWGGAISANQSEGFYLDGGKGLSQFDKLPLNDKRLKD
                     VCLDEDNILNENNQYYPSHIGIKFCENYKEDIAMLAEIGFKCFRFSISWSRIFPTGEE
                     SEPNEKGLQLYDNIIKELKKYNIEPLITISHFDIPYSLVEKYSGWADRRVVNLYVKYA
                     EILMKRYKDDVKYWIPFNEMNMIMHIPYIGAGLTFIADENQLQKKYQAAHHQLLANAK
                     TIEIGRYINKEFKFGCMLAAGKTYPYTCKPEDVFATLEHERYNLFFSDVQVRGVYPSF
                     MNYYLKSNQIKLIIKEEDLSTLKDNTVDFVSFSYYSSACSSARAEGLEKSKANGPETI
                     KNPYLPKSNSVWQNDPVGLRITMNQLYERYQLPLFIVENGLGTQDIVNEDGKIIDDYR
                     IDYMKEHIKNMILGVNEDGIELIGYLMWGCIDVTSVSEGKMTKRYGIIHVDSDDYGRG
                     SFKRTKKQSAFWYKKVIETDGEILFNDMETHA"
     gene            complement(16382..17269)
                     /locus_tag="KOU88_002819"
     CDS             complement(16382..17269)
                     /locus_tag="KOU88_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK3212687.1"
                     /translation="MAIYLEMPKLIHEFPFRSLSNEGEVLTTPHWHKEIEILLITEGV
                     VNLFINDKPMQLKKGEIVIIKGGDIHYILPSPGSERLVFQFDISFFNDLILLNEEKES
                     LINLFSSIKKCSRDWSAKIRKSVFDILIDIYNEDLYKIEGYSYAIKGKMYNLIPILYR
                     QIPREIEENTVEYEINSKEILERLNNIFKYVEKNYKQPIKLEDVSYEVGFSVYYFTKF
                     FKKNTGKTFITFLNEYRLEKAKWILLNNNISIVDLVEEVGFGSTKTFYRVFKEKIGVS
                     PLEFKKRYNSLEKKGSVSK"
     gene            complement(17369..17818)
                     /locus_tag="KOU88_002820"
     CDS             complement(17369..17818)
                     /locus_tag="KOU88_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3212688.1"
                     /translation="MEIREILTEESIILDLKSTTKEGIIQELVDKLYDTGSITLKSKF
                     IKALKHREKIGSTSIGYQMAMPHGKTKYVKKASVVIGKSKKGVDWPSIDGLPVKVIIM
                     FAMPQSGGNEDMILISKIAYILGGKNIGERLLNAHTKKEILDIFYEV"
     gene            complement(17808..19715)
                     /locus_tag="KOU88_002821"
     CDS             complement(17808..19715)
                     /locus_tag="KOU88_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3212689.1"
                     /translation="MLVSRQIEFLKLILNENKYRPIKYFKDKLNVSDKTLQKDLKMIE
                     KYLETFNIKIDIKRGYGILIEDLAKKNIDLINSLNIQSKENKSLSVEQRRMEILKYLL
                     LNSNNITSINQLADKYYVSKTSIVNDFKYIEAWIKEYNLKLNKTLEGTKIIGKEVDIR
                     KSIAKMMDDLLDENYEQHDISELTRLDSATFSALINLFDIDSIIFVETIITELEYNLG
                     YTINQPYYINLITHILICLKRIEEGNQIESQEEREISVDNLDELVYKNVTTLIDKIEN
                     RYRVKITKDEIMYIYIFLVSSGFSSENNSSYNDESDRLSESEKVSSIMIENMSRFLNI
                     NLKNDDLLQKSLASHVRPMLNRLRYDIQIKNPLLGEIQERFSDVLGLCMMTINIMTEY
                     DNLKNISIDEVSYLATYFQAAIERNMSSKRVIVVCHTGYGTSQLLAARLKREFPEWTI
                     VDIVPMHQLSKRNLDDVDFVISTVNLDLKDKLHIVVSVLLMENDINNIKNALLSKPKK
                     SMNLDTNLLGIYLEDNIYFNFDVAQMESLIGVNLGSKYESISLGKDLNIYIHKQSKLN
                     KGIMNVNNVTRTIDIYLEISNQSFLKNILMEISNLYRQKNYINYIIDCKSKEDIKILF
                     KNNLLEKTNGN"
     gene            complement(19983..21878)
                     /locus_tag="KOU88_002822"
     CDS             complement(19983..21878)
                     /locus_tag="KOU88_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3212690.1"
                     /translation="MIGKILRSDCIVLDKQLQTKKDVINYMANHLYHGNYINNKEKFI
                     ADINKREKESSTNMGNLIAIPHAKSNVVNQPVMMYLRTDREITDNDGQKLRSFFMIAV
                     PESGSDEHLKIISKLATYLMEENFLKHLLSAETPYEILSIFNNKAAESGDFSNNQNKG
                     LIVGITGCPTGIAHTFMAKKALEEAGQELGYEVKIETHGAIGVENKLTKEDIKRAEYV
                     IIACDKEVQLSRFIGKKVLQKKVVDAKNVSLAKNLIINAENGMAKEIKPGGKTLEDSK
                     EMLQGSEKKGVYKHLMSGVSEMIPFVVIGGIGIAIAFMFGIFASDPTHETYNPIAGFF
                     GQLGGDSAFKLFIPILAGFIAKSIAGRQGFAPAMIAGFMAVIGGSGFIGGMVAGFATG
                     YIALGVMKITENLPDVLKGVNAVLICPLLIAFTSGAIMFFVVNTPASWLNEALQSWLQ
                     SMSGTNKVLLGAILAGMMASDMGGPINKTASAFGLAMFSSNIFEPSAALMVGGMVPPL
                     AISLAMLIFKNKFTKEERKSSLPTAIMGASFITEGAIPFAAADPLRMIPANIIGSCIG
                     GAICMSLDITLMAPHGGIFVIPFACSAPVAYIACILIGTVVTALIIGVTKPTIRSENS
                     EVELLGA"
     gene            complement(21914..22792)
                     /locus_tag="KOU88_002823"
     CDS             complement(21914..22792)
                     /locus_tag="KOU88_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBK3212691.1"
                     /translation="MLINMKEMLKVAQENQFAVPAFNIGSGQILKAVVQSANEKNAPV
                     ILAIHPNELSFLGDSFVASCIEEANKSKVPMVIHLDHGENKEQILRAIRCGFTSVMID
                     GSHLPYEENVAISREIVEIAKGLNVSVEGELGTIGTTGTSSEGGTDEIIYTDSKLAKD
                     FVEKTGVDTLAIAIGTAHGIYPKGFKPELKLDLLKEIREVVDIPLVLHGGSSNPDEEI
                     AQAVKLGVCKINISSDVKSAYYKKCRELLEQNPSLYEPDTIYPPCIKSAREVIEFKMN
                     LFNAIDKLKCFYKNKN"
     gene            complement(23335..23505)
                     /locus_tag="KOU88_002824"
     CDS             complement(23335..23505)
                     /locus_tag="KOU88_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212692.1"
                     /translation="MSALLYGVCNKPILISIVTNMQEFKIGVSMNYGVLVIGICYIAL
                     GIIFKLDRKRFT"
     gene            complement(23902..24114)
                     /locus_tag="KOU88_002825"
     CDS             complement(23902..24114)
                     /locus_tag="KOU88_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212693.1"
                     /translation="MAILMKTKIKEYREKLLMTQNELAKLVGVRRETIVHLENGKYNP
                     SLKLAVDIAKVFDTTVENLFEFIEEE"
     gene            complement(24115..24531)
                     /locus_tag="KOU88_002826"
     CDS             complement(24115..24531)
                     /locus_tag="KOU88_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212694.1"
                     /translation="MSKSETGVRSKLILELLVITYFFIAVLSTKYIFKGPSTASLPGL
                     SWLIVFGCYSIYNKKYNDLVDESSEFILSKVNKIAIKIMIYSIVIISIFFATPYTSNI
                     NISNLDTGIILIAVLFIQSLSKLVLYIYFDKRGICN"
     gene            complement(24599..25012)
                     /locus_tag="KOU88_002827"
     CDS             complement(24599..25012)
                     /locus_tag="KOU88_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212695.1"
                     /translation="MSKSELGVKTNLVSELLMISYFFIDSLLKKFIFKYGNLCITFII
                     LFAFWACDFMYNKKYNDLVDEASKLMLLKVDHIASKIMLYSILLIAVFFSANYTRGLD
                     ISNLDIGVILLAILFIQSLSKLILYIHFDRKGICN"
     gene            complement(25846..26475)
                     /locus_tag="KOU88_002828"
     CDS             complement(25846..26475)
                     /locus_tag="KOU88_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBK3212696.1"
                     /translation="MKNRKVYMYVFDTMSDWEVAYLTAELNTGRYFKKGLKPLKVITV
                     GIDKNPIITMGGLKVLPEITVDEFNMESKDLLILPGGNTWLSMNHEIILEKVKEALIQ
                     DSIVAAICGATLGLAKKGLLDFRNHTSNDLEFLKMVIPNYSGEKYYKTESVVSDENLV
                     TASGIAPLEFTFQVLKLLDVFESEALNSWLNLYKTHDSKYFFELMNCNK"
     gene            complement(26554..27516)
                     /locus_tag="KOU88_002829"
     CDS             complement(26554..27516)
                     /locus_tag="KOU88_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017561613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBK3212697.1"
                     /translation="MAKIDNMMSILWILNSDKKITAKQIAEKLEINIRTVYRYIDVLS
                     ASGVPIISDTGHNGGYSLLNNFTKAPLFFDIEEQKSLLHAALFAKKEGYFLDEALDKS
                     ILKLKMYSNQKQEDILTNHLRALEVIKPIGKVSIESVLKKLENSILKELSVEINYHAG
                     RKAKSKYRIINPYGIVHWNNNWYVVAFCNMRNEVRSFRVDRISEIIETSNTFNRPTEF
                     SASEFFIKGIIPEIKDEQNIIQLVVEGSIDSLDSLSQHWFLGHYLKERTPNKIIFMLE
                     EEVICKYIPNILLPYRKTIQVIEPLSLRKKIIEDLLELIDYYQI"
     gene            complement(28196..31831)
                     /gene="cbpA"
                     /locus_tag="KOU88_002830"
     CDS             complement(28196..31831)
                     /gene="cbpA"
                     /locus_tag="KOU88_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding adhesin CbpA"
                     /protein_id="HBK3212698.1"
                     /translation="MQQKCKKKALSMILSISMGLGSVASFNASNTFADTIEESTNAGN
                     AEGDTNAGNAGGDANAGNAEGDANAGNAEGDANAGNAGGDANAGNAGGDANAGNAGGD
                     TNAGNPEGDANAGNAGGDANAGNAEEDANAGNAEGDANAGNAEEDSNAGNAEGDMNAL
                     VVEEATAEDPTSVGDFKISGGEINVDFKFASGVLTILSGKQMTIQNNNPNTPTTHRIV
                     IPKDVKAELIFDGVNIKTASNSPFTLTPDKDGGAYAHVILQDGSENKLESGDVYYPGM
                     RAGKGTTLIIDDSVVNRDIEGEFIVPEGGKIPRDVTLENGDKLKKGDRLTLLDSNNRG
                     SLKVVGNYYSAGIGGGNTESGGNIIINGGAITAIGQESSRNTGYGAGIGGGGNGSGGD
                     ITINGGTITAKGAYHGAGIGGGYYTTTKNALSPSVVDPSTGSGYSGNITINGGLSYSY
                     GGAHGSAFGDGCVNPGTNRGYRILVTGGTILPYMTGVGDWIFDLSATTGDVIVTGGSL
                     KATTFKSLGGAVAYGDLEKKTKVFMNKISLKYLGQDKVSTTLVDDFKMLIDGKIYPYG
                     APSYTDDQGVLYLWFSEQFKGSEVSVNLVVIDKITGGNIKPDDFYVKDIGSGSQFLKQ
                     YEEFTIDDTPPYLIIKRYDGLPFEEDVEKSFLDWILKDGGIPIITPKGEKLTDKKFMT
                     ISSQRLNEETMEPDTNLGSDDLTKQVDAGKYQLSITSTQFSNVYPFNEAYWGHRAYYK
                     AEIIPADTETSLVVEESKAKTDVFKPTDTFTLNVTISPDKKEGPDCASPRGYVQFYIN
                     GKEYKDPVELKTHNKGSESHNYSTASIEWRPLDSNHHIFTTEQTITVKYIGDDINYIE
                     GSEDEKKLKLDVTNVDVDGDGIPDINIDTDGDGRPDINIDTSGDWKPDINIDTDNTGE
                     WKPSTEGGNGDGIWKPDKNIDTNGDGNPDTDYNRPAIDTDNDGVDDYWKPDKNVDTGS
                     GGYDTGNPNLNKPDPDNGGNSKPDPDNGGNSKPDPDNGGNSKPDSGNGGNSKPDSGNG
                     GNSKPDSGNGGNSKPDPDNGGNGKPDPDNGGNNKPDPDNGGNSKPDPDNGGNSKPDID
                     IDIDTDGDGKPNINIDTDGDGKPDINIDTDGDGKPDVNIDIDGDGKPDVNIDIDGDGK
                     PDINIDTDGNGKPDINIDTDESLDSNVGQNVQTGDQSNIMLDLALMFISLFFLIKNLT
                     NKYLRRK"
     gene            32100..32671
                     /locus_tag="KOU88_002831"
                     /pseudo
     CDS             32100..32671
                     /locus_tag="KOU88_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427525.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
     gene            complement(33683..34345)
                     /locus_tag="KOU88_002832"
     CDS             complement(33683..34345)
                     /locus_tag="KOU88_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212699.1"
                     /translation="MKMLKVIDIKKIYGKGENEIKAVDGITLEIEPHKFSAIIGQSGS
                     GKSTLLHCMAGLDKPTLGNVFMDNLDLYTLSDEKLSNLRSKEFGFIFQNYNLIPVINV
                     YDNIVLPILIAKGKIDNNYINDLITKLGLESQINKFPNELSGGQQQRVAIARSLANKP
                     SIIFADEPTGNLDSKTTNEVMNLLKYCVNEYKQTLVMITHNDEIAKMADCIITISDGK
                     VI"
     gene            complement(34362..36917)
                     /locus_tag="KOU88_002833"
     CDS             complement(34362..36917)
                     /locus_tag="KOU88_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBK3212700.1"
                     /translation="MGIYLKMSLAYLKKNKLRTLLLIIGVMLGVMLIFGPSVIKDSQN
                     ENNVVAIHELYSGYHVEFSDLTLDDAKKLETDEKVSKGNSVQNLGRISDKKGNSFILT
                     SSNEEYLKSRYNKIIEGRLPKNNNEIVLEKKALEAMNLSEGVGSTLNLTIKKNYKDTN
                     GSNQLFSINKEFKIVGVMEKPKGYYDVVWQYEAVTYGNDETNNIIPNDAISYNSILSF
                     KSGWRNIEGECDYLMKKYKLGQKSFLPNVPLVRELRYVEDDKSDPNVFKRNVLITTVS
                     IIFIFNIFNITLNQSVKEMGLFRLMGAKKRNVRCMIIYQALIITIIGILLGLVAGVTY
                     SYIGISNYNEALYSEAGLNPKLYINNEIVIKAILVGIISVFISCIIPTFKIGKISPIE
                     SIINTDKIKNHRSRLGIDRLVSKIFGFYGFMGLKNIGRNKVRAAISMLSIALGGYIFI
                     TTFSSMQEEVNSKIEDMQNRYNITMQFGVNADPQISKYTDSDVENIEKIKGVKSIHKI
                     QITNGMFTFNNKDINKEFTTYNGVEKKEIMEDKLVLKLYDDDYIDEKLNDFVEEGSLD
                     DIKKDTDGYPNVAVYNYFYDIVDDHTIKPIFKELNIGDIITVKIPVEENNTIVYKEMK
                     VRVAVILKDEWIAMGDGDFMPDLEIITSNIHSKNITGEQKYTQLGINLENPYDEIVNN
                     EIQKISRSIPGSLFNSRLSYHEMSESIYKSYIKSQIAIIALVLIIASINIFCTIRTNL
                     LIRKKEISTLRALGVSLKNMKKMLIYEALAYAVFSFIIAMIPSFINLVKFTNWNNDAY
                     INYGIENFMSFTFPIKESLLFFAISVFVCLIAVVVSNRDFESMNIIEGIKENE"
BASE COUNT        12029 a         6470 c         3878 g        14760 t
ORIGIN      
        1 taaatactta aatttagttt tatttaaacg ctctagtgat atttttaaat aaattttaat
       61 aaaaatcatt ctattttgtc ataaatcatt tatctggctt atatttaaga tatattggtg
      121 gatactttac actttttaat tcctcattac ttcttaaaag tttattatta ttttccatat
      181 cataaatttg taacattact ttatttacat atagagcata ataattatca ctataaaaat
      241 attgatactc atatcgaggg tcatctttgt aatacacttt gtatagtatt ccttcgtaac
      301 ttgccttctt ggctttttct tttgtaatac tttttatatt atcttttgaa atatcttgtt
      361 ttaccatata cttatcaata tatgtttcag catctttcca tggtttaatg cagtttttat
      421 atacaacaaa ccctgttaca cttataatac ctataattaa tactataaaa ataactttat
      481 attttttcat attgatcctc cttcatttat tatttaaaac tcgatataat gcactaaaaa
      541 aaggatgtta tcttttttat taaaatataa catccctcat atttagcatc aatatatatg
      601 ccccaactgg taggttaaaa gaccccactg tcagtacttt gattaaatta catgtatgta
      661 tatatatttt taacaaatct attatatgtc aacttgtcta ctattacata taatctgtaa
      721 tattacatct gctgcttttt ttgagcctcc tgcattataa aagctttttg atagtttagt
      781 tgcattttct ttatattcat tgtcatttat aacttgaaat actgcttttt taatactttc
      841 tgacttatcc tcttttaaca taattcctgc tcccaaatga acaactctct tagctaccat
      901 tctctgctcc gaatgttgag gaaataatac cataggtact ccataatata aactttcatt
      961 aacactattc atcccagaat gagtaacaaa cacatcagtt ttttgaagta tagcaatctg
     1021 ttcaacacta tttttgacct caaaattatt tggtatattt cctaaacttt taatatcagt
     1081 acttctacca acagacataa tcacatcaac atcagaatct ttaaatgcac ttatacagtt
     1141 tttataaaag ctaacatttt tattattaat tgtaccaagc gaaatatata ttagctttct
     1201 ttttctctct ttaggttcaa taatcaactt tgatactgat ggacctacaa atgaatactt
     1261 actagagaag gtttctacca ttggttgaaa ttcttttgat gtatatacaa tggtatccgt
     1321 atcattatca ttagaaacta tagaaataaa attttttact tcataccctt ttctttgtaa
     1381 aagctttatt tttttattaa tgcgtcttac accaaaaatc atacgtataa tttctataaa
     1441 gttttgtttc atcaactttg ctgtatgttt attaaatgca aaagttgttg tagagcatac
     1501 atatggaata ttaagttttt gtgcaaataa ctttccccaa aaacttaatg aatctgatac
     1561 aatgcaatct ggattaaaat ctttaagttc tctacaaact ttttcatcta aagaaatagt
     1621 agtatctact atcatctcaa ttaatccagg aaaatcctta ccaatttttt tctcatctcc
     1681 agggagtaat tctggaaggt atttatcaca acaaataaat tttgctccag caccttcaat
     1741 tttatcttta aattcattaa aagaataata caatacctca tttcctctat ccactaattc
     1801 acgaactact tcaatagtag gattagtatg accatatgca ggaatgctaa aaaatactat
     1861 tttactcata tttcatacct ccttttataa tttttttaaa tcattcttct ttacgtacta
     1921 ctcccacatg acctataaaa tttatcaaat cacgttgatg aacaattcct aatcctcttt
     1981 cctcatctcc aagtaccaat aatttatctc ctgcatttat attaaatact tctcttgctt
     2041 cttttggaat gacaatctga ccacgttcac caactacaac tgctccaaag aaaaactttc
     2101 ctttaggagg tactataata cctgtttttt cttccgaatg attaactaag tcatctagtt
     2161 taacattgta caattttgca agtttaatgc aactacatat atcaggaata gattctccac
     2221 tttcccattt tgctattgat tgtctagaaa cattaagttt ttcagctaat tcttcttgtg
     2281 tatactggtt gatttttctt agacttttta aattctcatt aatcatattt ttcatacctc
     2341 ctatgtttat aatattggat ttattattta aattctatca actaatctta acattcatat
     2401 atatatttat atacttttat tatataaatt tattattcag gtaacatatt tccttaagtt
     2461 atcgtaaaca aaaaaacaag cacaaatcta ctaactgttg ttaaagtatt taagttaagg
     2521 tcatttacat tatcaaatat ttctacacct ttaaaataac ctttatattt ataatctttc
     2581 ataagcaaat tattatccct tctcatatac aagtccagtt gatgtcttgt tgctaaattt
     2641 aatggtaatc aaattcttta ccaataagta taaaaattac taatgtgtta taattttctt
     2701 aactactaaa ttttacatac atttgaatag aatatatcaa taaattacta taataaataa
     2761 aaaattaaga gttaaaataa aaaatagtta gggagatatt attatgattt tatattttag
     2821 cggaactggt aatagccgat atgtggctcg taaaattgca caagaattaa atgatgaact
     2881 gatatcacta aatcaactta taaaagagga aaaaacagat gaattaatat cagcagataa
     2941 accattcata tttgtatgtc ctacttatgc atggagattg ccaatagtgg ttacggattt
     3001 tataaaagaa acaaaatttc taggaagcaa cagagtttac tttgtaatga cttgtggggg
     3061 agatacagca aaatccataa actatattca aaaactatgt aaatataagg aatggcaatt
     3121 aaaaggtatg gcagaaatta aaatgccaga gaattatata gctttatttt ctacaacaga
     3181 caaagaaaca tcaaaacaaa tgattaaaga agcagataaa caaatatata ggattatttc
     3241 tgatatacga aatgaaaatg aatttgaaac tattactcct agtggcttag gaggtacaat
     3301 taaaagtggt ataataaata cagtttttta taagacaatt attagtgcca aaggatttca
     3361 ttatactgat aaatgcattg gctgtggaaa atgtgtagag ctatgtcctt taaataatat
     3421 taatttaaaa aacaaaaaac cagtttggaa aaataactgt actcattgta tggcatgtat
     3481 ttgtggttgc cccactgaag ctattgagta taaaaataaa actcaaaaca gagaaagata
     3541 ctatttagaa taatatattc ttaatattta aaccattata aaatgaacta tacccattgt
     3601 tttatacagt tttacatatt ttaactgtct cctaagatgg gtatagttca aaagatagtg
     3661 tctcaaagtg aacttttaag ttcctaaatc aatctttttg tattaaatca agtataattt
     3721 aatcaccttt tcttatatca ttttcactaa tatgttgtat tccaacaaat ataagattta
     3781 ttagctctgt tagtgacttc cattgtgatt tttttgaatc aagataataa taatttttcg
     3841 ttccttctct acgtaaatta acaatctctg cttcttttaa tatcttaaga tgatgagata
     3901 cagcaggacg agaaagatgt gttttttttg tgatttctcc cactcgtata ccattaaaat
     3961 cactctctaa gagagcaatt aaaatcaatt gtctagtctc atcacccata gcagagatag
     4021 ctttgcgaca ttctttaaat ttagacgtta tttcttgcat tctttgttga cattcttttt
     4081 ccataaaatc caccctctct tataagtatc taacagttgc tacttctttc tgtgcagtac
     4141 gtctatattt aacatctggg tatccaatta ctaatgttgt aagaacatga ttactgcgtt
     4201 ttagacctaa aagctttttt aactttggcg aattatttgc tacatctgaa aaatatccac
     4261 taaataaaac acctaggcca taagactctg ccattaatgc catatttgat gctgcaagtg
     4321 aaccactaat cttatctttt gtaattatca ttattgcaat aggagcatgc ttaaagaaaa
     4381 agttatcgtc aatctcaact tcttttgaat atttaatagc tatatttgca ataggtttta
     4441 tctttctaaa aaatttcact gcttcgtttt cataaattga ttttttattg tctaaaacaa
     4501 tatatgatac atcttgtgaa tttttagcac taggggtata cctacctgcc tcaataattt
     4561 gctttataat ttctgaagaa acttctttat ctttaaattt acgtatactt cttctagatt
     4621 taattgccat tagtaattca tctgaatcta gctttggctt atttgtaagt tctataggag
     4681 gttcatcaaa tcctgtcaag gtaatagctt ttgtgggaca tattgctgca caatgtccac
     4741 acattagaca atcttgtttt ttaattactg actttttatt ttctataatt atattgttta
     4801 ctggacaatc atttttacaa agcccacatc caatgcaaag ttctttgtca acttctatta
     4861 tatgttggta tttcatattc attcatctac ctttcgttta ttagtttaaa ctattataac
     4921 acgtagacat tttttatatt cattggtaaa gaatttgatt accattaaat ttttaatttc
     4981 tctattaaat aaatttttca tagaatttta aagtatcata gtttatacat aataaaaaag
     5041 acaagcttaa aacctaagct tgcctttttc atcttttatt acaaagtaaa ttgcacttac
     5101 ttcccatact tcttaacaat tttattttct aaaattttat ttgtgaatca tactattgca
     5161 taaatacaat gtaaaataat tctgtattga ttttctatag ttaaaaaagt taaaaattat
     5221 acttattatt aatttttata ctcttcttat ttaatacaaa tttcttattt aacatagatt
     5281 tcttgtctaa tataaatctt caccatttga agcaattact ttcttatacc attcaaaact
     5341 tttctttttc attcttctta gacttccatt accactattg tctctatcta catatataaa
     5401 tccataacgc ttttccattt cacctgtacc agcacttact aaatcaatag gtgcccatgt
     5461 agtataacct aataaatcga ccccatctat agaaactgca tcatgcatag cttttatatg
     5521 ttctcttaga taatcaattc tgtaatcatc ttctacataa ccattttcat cagctatatc
     5581 tttagcacct aatccatttt ctacaataaa tagtggcttt tcatatctat catatacatg
     5641 atttagtgta attctcaaac ctaatgggtc aattggccat ccccattgac tgtatgaaag
     5701 atatggattt ttagcagatg taaatatgtt tccttcagcc atatcatctg cattttcatc
     5761 ggttctaaca caacggctat tgtaatatga aaatgaaata aaatctactg tatatttatt
     5821 caataattca atatcaccag gttccatttc tggtgtaata cctttttgct ccatatactt
     5881 taacgcatag ttaggatatt tacctttaga ttgtacatcc acaaagaagt aattttctct
     5941 atctaacttt gtagcttccc atacatcatt aggattacaa ctataaggat atacacttcc
     6001 agctgcaaac atacatccaa ttaagttatt tgaatcaact tcatgtgcta ttttagttgc
     6061 aattgcacta gctacaagct catgatgggc agcttgatat tttatctttt caacatcttc
     6121 accttcttca aagcaaatac cagcacccat aaatggagca tgtaaaatca tatttatttc
     6181 attgaaagtt agccagtact tcactaatcc tttatatctt ctaaagataa cattgcataa
     6241 tttctcatag aaacctatca tttttcgatt acgccatgca ccatactttt taactaaatg
     6301 cattggacaa tcaaagtgtg taatagtgac taaaggctct attttatatt ttttacactc
     6361 cttaaatata ttttcataaa attgaagtcc cttttcattt ggtgtttctt catcaccttt
     6421 tggaaatatt cgactccatg caatgctcat tctatatact ttaaatccca tttcagcaaa
     6481 taactttata tcttctttat aattatgata catatcaata ccagttttag ctggataata
     6541 atgctcatca tcaaaatcaa acatttttag tttccctgta ataactgctg ttctatcttt
     6601 tcctgttgga catacatcta catttgccaa tcctctttcg tcttcattgt atccaccttc
     6661 acattgattg gccgcagtag ctcctcccca taaaaaatca ttcttaaaac tcatagtcaa
     6721 agcctcctaa aattataacc aaagcactag attatgctaa tacctcaatc tttactaaaa
     6781 taagactgta attagattgt cttctaattc aatattttta ctttctgttt ctactacatc
     6841 taaaaattgt gatgaatttg taataacaat tggagttaca gtactatacc ccaactcttt
     6901 tattgcataa acatcaaagt ttaatatagt ttgacctttt gtaattctat caccttgttt
     6961 tatacatgcc tcaaaacctc ttccctctaa ttgaatagta tttaatccaa tatgaataag
     7021 cacttcaaca cctgtatcag aaagaatccc tatagcatgt agactaggaa ataaggttgt
     7081 aactacccca tctactggag caactacttt tccatcacta ggtattattg ccactccttg
     7141 acctagtaca ccagatgcaa atgctgcatc ctctatatca cttaatttta atacttcacc
     7201 ttttatagga cttgttacta tttctctttc taatttagta gacttgactt cttttatttc
     7261 ttctttaccc ttatttctta cttttttaga ctcttctact ttctcatctt tatataaaat
     7321 catagttaat acaaaagcta cgaccattga tatagctata ccagaaagag ctactattaa
     7381 gttacccatt cccccatctg gttcaatcat tgctggaagt tcaaatattc ccattcctcc
     7441 agttataaat tttctaagat taaagaatcc atagaaagcg cctccaatac cactagcaat
     7501 acaacttatt ataaatggtt tctttaaagg caataatatt ccataaattg ctggctctgt
     7561 aactccaaat ataccagata taaagtttgg tattgccatc tcttttagtt ttttatcttt
     7621 agtcttgaaa aatattgcca acacaactgc cgaacttgca aatgtacagg caaagaatgg
     7681 catcataaca ttatcatatc ctaaagtcat aacattgttt atatatacag gaataaatcc
     7741 ccagtgcata ccaaaaataa caagaatttg ccaagtaaat cctactatag cacctgccaa
     7801 tagtggacta aaatctctta ttgaaattac aatttgtgaa ataagtgtag aaccaaatgt
     7861 tgctatagga cctataacta taagtgcaac aggcactgtt attaataatg taagcattgg
     7921 cacaaagaaa aacttaacta aatctggaac acacttatta aataattttt cacacctaga
     7981 agcaaaatac actataaata taattggtac gactgttcca gtataatcaa ttgatacaat
     8041 tggtagtcca aagaaatcaa tatatactgg tgatgcaaac attgttcctt taaataaagt
     8101 gtacatcaca tctgctcctg ctgatatact gctaccttgt atagcaggat aacatactgc
     8161 agctcctagt gctaatccca acattggttt taatccaaac ttcttagctg aagtatatcc
     8221 taagaacaaa ggaaggaatg taaataatgc atctcccgct gcatttatta ccatataacc
     8281 accagataca tcactatata atcccattgc tacaaataat gcattaaatc ctttcaacat
     8341 accacaagct gccattatcc ctaacactgg ctgaaaaatt cctgatatta tatctatacc
     8401 tttatctagt atattacctg attttttagt ttctgaactt gtacttgaat catctaaacc
     8461 aattatttca actacatctt tatagacagc ttcaacatga tttcctataa ctacttgata
     8521 ttgtcctcca cttttcatta cagtaacaat accttccatg ttttttaata cattgtcatt
     8581 tgctatactt tcatctttta aagtaaaacg taatcttgta atacagtgta ctaatccact
     8641 aatattttct tttccaccaa cattgtttac tatctcttgt gctaattgtt tgtattttcc
     8701 catttttctc ctccatattt cgtttaaatt aattttttga aatttgaagg tttggccaac
     8761 tcaatgttac catccaacca taagtataat tttgttagta tcactccttt caatcattct
     8821 taatatactg ctgaaaaatt atttcactta catatttgag tctttaacta ctttagctaa
     8881 atgtattgtt aaatatataa gctcatcatc tgttaatatg tagttatatt gttttttaat
     8941 gaaattttta attttaacta cacattcaaa ctctttatta tatttagatt taataatgct
     9001 tagtaattct ttgtctgtct caccttcatg tgcgctatct aaaagcaatc tttgcgcaaa
     9061 aaactttaaa tgcattataa atctataata aaacactgat tcttcatgaa attctatcct
     9121 aaaatgatac ctaactatgc taagtacttc ttgtattagc ttcgtaatat cagatgccaa
     9181 agtatgacct tcacttaact gagcattcac tatatgaaag gctataaatc cagcctcatc
     9241 ttctggtaat tttatacctg ttttgttttc aataatatct agtgctttca ttccaatttc
     9301 aaactcttct ttataaaatc ttttaatttc ccaaaggatt gcatttttta catttattcc
     9361 ttctttcatc ctttgaattg cagaatatgt atggtcactt aaggatatgt aaatactttc
     9421 atttagcttc ttgtttaact ttatttgtgc gtattctata atttcacttg ataatttcat
     9481 gtgttctata ggaatattat tgagtaattc ttgtagtttg tttgatattt ctttatttga
     9541 tattctaaat actttattta ctttagtttt atctattaga ttgccttttg atttttgata
     9601 accaattcct ttacccataa cgataacttc ttcatcatta tcatctaatg tgattacaac
     9661 attattgttt aatatcttat taattatcat gattatcctc cttttaagca taaaaaaagc
     9721 ttatccataa taatgggcat actccttcct aggatactgc tattattaat gaataagctt
     9781 agcttgtact taaacaatta ctacctaatt ccaattaata tgataaaaca tcagacatat
     9841 tttgtcaact ttttatttcc atatacttca tcaatctttt atgttgcttt ttgtcagttc
     9901 taataattat tcttattaat attaacttat ttctttgcat caatataaat acaaaacaag
     9961 ttatagtcaa taataataaa aattctatta atgtaaatag ttaatattat acttcctcta
    10021 ctacattatc tgtactttat ttaacatttt tttcaactcc aaaaacatat gtcataataa
    10081 atggagcaac caatgctata aatataacta taagtccatt tactatattt gaaatcccct
    10141 tttcccctga taatccaagt actgccatta tactattttg tggaacatat aaagtcacat
    10201 gagtaattcc tgcaaataac cctgcgattc ctgctcctat agatgctaac atagcaggtt
    10261 ttttaagttt caatgtaact ccataaagag ctggttcagt tatacccatg atagctgata
    10321 tccatgcagc tgatgctaac tgtttcatct tactatcttt gcttcttaat gctacagcta
    10381 atgtcgcgcc accttgcgct aaattagcac aaacttgaga tattaatatt agcgattctt
    10441 gtcctgtagt tgcaaatgct gatatgaata taggagtcaa tgcatgatgc atccctgtca
    10501 taacgataaa tggcattgca gctgctaata aacaaaccat tataaatcct aaccttcctt
    10561 gtagtaaatt tattacacta gctaatccct ctcctaagaa atttcctatt ggtccaatta
    10621 ctattaatgc tattggcgca cttattaata atactaaagt tggatttaaa attgttttta
    10681 acatgctagg tgttaattta tcaatgaatt tttctatata tgacatcatc catactgtta
    10741 aaagtgcagg gataacagat gctacatata taacaccttg aattggtact cctataaatg
    10801 atatagggtc cccacttgat acccatgcag agaaatttgg atgtaaaaac acacctacta
    10861 ctataactgc tattgatgta ttaacattaa attttttagc tgcatttatt gcaagtatta
    10921 taggcataaa gtaaaatgct acatctccta ttatatctaa tactctatat gtacttgaat
    10981 ttgatgatag ccaattaaaa gtggtgcaaa gagataatat aacttttatc atcccagatg
    11041 ctgtaagggc tggtatcata ggtgtcatac aaccagttat tgtatctatt atattattta
    11101 aaatactatt ttttttattt tttatatcgc ttttaatatc tcctgtggta tttatcccct
    11161 tatttattat tgcattaaat acaacaccta cctcattacc tattataacc tgatattgag
    11221 ttgaagttga gtttactcca actaccttat ctatagattt taatttatct gcattgactt
    11281 tcttttcatc ttttaagatg aaccttaatc gtgtcataca atgagttaag tcaattatat
    11341 tatcctttcc tccaaggcca tcaattatca attgagctac ttcttcatat ttattcttca
    11401 taccttatcc tctcttttaa aataattttt aatataattt taatccaaat taatcttttt
    11461 actccaagct tgtaatagtg tattgcaatt taataagcta gtatcttcta caatatggtc
    11521 acattttcct agtacttctt ttttccccac accaattgat gtcatattag cagcatttat
    11581 agctttaata cctgaataag aatcttctat tcctacacaa tcatattgtt ttaaatttag
    11641 aatcttgctc ccttcaataa aaatatcagg atatggtttt ccccttttta ataaagatgg
    11701 atttactata caatcaaatt catcttttat tcccaaagat tctaatatcc taggtgcatt
    11761 cttactagca gatgctattc ccaatttcac attatttttt ttaagttctt ttataagctc
    11821 atttatccct ggtaatatat ctttatatgt taatgagttt attaacttta tataaatgtt
    11881 atttttttct tcacacacct ttaacttttc ctctttagta taactatcta ctttattagc
    11941 agataacaat attttatcta atgattcttc cctgcttatg ccttttaatt tttcattaaa
    12001 agtttcatct atttctatat ctagcgattt tgctatctca tgccaagctt caaaatgata
    12061 cttagcagta tctgttataa ctccatcaag atcaaataag actgctttca tattaattac
    12121 tccctttaaa acaattatta acttctatta tgttctttga taattttatt tctttattat
    12181 catgtaatat ggttatattt ctacctttga ttaacttata ataagattta tattcttcta
    12241 tatttacaga aactaaatta tctctaaata atatattaaa tttaatattt ttccagtgtt
    12301 taggtatcct tggttcaaaa cttaatttat cattttttat tttcattcct gcaaatccat
    12361 atactaaact catccatgtt ccacccatat tagcagcatg tattccatca cttgtatttt
    12421 tttgtaggtt attaatatcc attaatgctg tgtccataaa atagttataa gctttttcat
    12481 gatttccaat ttcacttgcc atcattccaa atattgacct tgacaaagat gaatcatgag
    12541 tagttatttt ttcatagtat tcaaaatctc tcttcttttg ttctaagcta aactcatcag
    12601 ggaaaagcaa cgctgaaagt acagtatctg cttgtttatt tacttgatat ctatatattg
    12661 ttaatggatg ataatggaga agtaatggat atttttcttt tggtgtattt ttaaaatccc
    12721 atactgattt ttctaaaaat gaatcgtctt gtttgcttat tttcttctct tcatcatatg
    12781 gtaaatacat attttgagcg gcatttatcc agtttttcac ttcatattct tgtaatttaa
    12841 cttttctaaa tacttcattt gaaaataaat tatgcttaaa tttatctacc atctgtactg
    12901 catatattaa attatactta gccattaaat tagtgtagta attattgttt actattgctg
    12961 tatattcatc tggtcctgtt actccattta tacagaattt attatttttt gattctatat
    13021 aatctccaaa ttcaacccaa aatcttgctg tttctataag aatttctaag ccattttgca
    13081 tcataaattc ttcatcatta gttgcttcaa aatacgttct aataccataa gctatatctg
    13141 catttatatg aaactgtgct gttcctgttg gataatatgc actgcattca ttaccattta
    13201 tagttctcca tgaatataag caacctttat ttattccaag ttctctagct ctttctcttg
    13261 atgcatctaa gattgagtat ctataatcta ataaagctct agcaatggat ggttgagtat
    13321 atataaaaaa tggtaatata tacatttctg tatcccagaa ataatgcccc tcatagccat
    13381 cacctgtaag accttttgct gatatattag tctttccatc tcttcctgct gattgataaa
    13441 tatgaaataa attggttttt atccccagtt gaagagtttt atcgccttca atctctacat
    13501 cagaggttgt ccaaaactca ttcattttct ttctctgaat atttttgact ttatcaaatc
    13561 caatattaca tgcttctctt aaaaccaatt ctaatgattt taaatgtgct tctgattcta
    13621 aacattttaa cgactccaga cattctaatg attttaaacg ttcttcattt agatttaaat
    13681 cagaatatac tctactatag cctacaacaa tttctaaatt taacctttca tcttttttgg
    13741 catagacttc tatttctcgc tcaatacatt catctgaaac attataggtc tcatttgtaa
    13801 tatttccaca agtaatatat gaatcaaacc cacaccataa ccctaatcta cttctttctg
    13861 taactaaatt cataaaatac ttattgttat atttttttac attaatttta aattgcttct
    13921 tatttataga tgccactctt gggtcatcta ctttttcaca attaaacttc tccatactat
    13981 tttccatttt atttttaaat tttatttttc cattaaaatt caatggtgtt attgtatatg
    14041 aaatcatcat taattcttct atatcttgtg atactaatct ttctatagat actttaactt
    14101 ttctaccaca agagttttcc catataaatg aacgtttaag aatcccttca tttaaatcta
    14161 gtatcctaga atgttcactt gtaatacctt ttgataaatc aaaataatct ccttcaatag
    14221 agaaatttac tatatgagca ttaggtaact tacagatagt ctgattttgt tttgcatagc
    14281 cataagcgct ttctccatat gtaattggag attcttcata aaatccattt acatatgtac
    14341 ccatattatc tacatactca ttattaaaat cagactcttc aatattccct ctaactccta
    14401 aatgtccatt agctagtgta aacagcgttt cattggattt tattgtatcc ttactaaacc
    14461 cttgctctat aagttggtcc ttagtagtaa atattaaact cataataaca ctcctttctt
    14521 aaaatgaatt atgcatgagt ttccatgtca ttaaataaaa tttctccatc tgtttctatt
    14581 acttttttat accaaaaagc actttgtttt ttagttcttt taaatgagcc tcttccatag
    14641 tcatcagaat caacatgaat tatgccatat cgttttgtca tctttccttc acttacactg
    14701 gttacatcta tacatcccca cataagatat cctataagct ctattccatc ttcatttact
    14761 ccaagaatca tatttttaat atgttctttc atgtaatcta tacgataatc atcaattatt
    14821 tttccatctt cattcacaat atcttgagta cccagtccat tttctactat aaataaaggt
    14881 aactgatacc tttcatataa ctgattcata gttattctta accctacagg gtcgttttgc
    14941 catacactat ttgattttgg aagatatgga ttttttatgg tttctggtcc gtttgccttt
    15001 gatttttcta aaccttcagc tctagctgaa ctacaagcac tagaataata gctaaaagat
    15061 acaaaatcta cagtattatc cttaagtgtt gataaatctt cctcttttat tattaatttt
    15121 atttgatttg attttaaata ataattcata aagcttggat acacacccct aacttgaaca
    15181 tcagaaaaaa acaaattata cctttcatgc tctaaagttg caaatacatc ttctggttta
    15241 catgtgtatg gatatgtttt tccagcagct aacatacacc caaacttaaa ttctttattt
    15301 atataccttc ctatttctat agtttttgca ttagctaata attgatggtg tgctgcttga
    15361 tattttttct gaagttgatt ttcatcagct ataaaagtta acccagcacc tatatatgga
    15421 atatgcatta tcatattcat ttcgttaaaa ggaatccagt atttgacatc atctttatat
    15481 cttttcatca aaatttcagc atattttaca tataaattaa ccactcttct atcagcccac
    15541 ccagaatatt tttcaactag agaataaggt atatcaaagt ggcttatcgt tattaatggc
    15601 tctatattat atttttttaa ttcttttatt atattatcat aaagttgtaa tcccttttca
    15661 tttggttcac tttcttctcc tgttgggaat attcttgacc aagatataga aaatctaaaa
    15721 catttaaaac ctatttctgc taacattgct atatcttctt tgtaattttc acaaaattta
    15781 atccctatat gacttggata gtattgatta ttttcattta aaatattatc ctcatctaaa
    15841 catacatctt ttaatctctt atcatttaat gggagtttat caaactgaga taaacctttt
    15901 cctccatcta aataaaatcc ttcactttga ttggctgaaa ttgcccctcc ccataaaaaa
    15961 tctttcccta atttcatgca tctacctctt tcacaatata aagttttata atttctatct
    16021 catatttagt tataagattt ttttcatact atacctttta aataattcaa tttaaaaatc
    16081 caatgatatt ttttactcac tataattaat attgtctatt ttcaatactt tcatattaaa
    16141 tatcaatatt agatatctat gtatataatt atatatatag caaatacatt tttatatcct
    16201 cattattgtt atcttattct catatattgc tgtatattta tatatataaa aggagttatt
    16261 tcgaaataga ggttgtattg agaactaaaa tttagacttt ataaatgaat ggaattttca
    16321 ttgttgaaat actgaaaata tatttgattt catataaaag aaagtgcctc atgaactaag
    16381 ttcattttga gacactccct tttttttcca agctattata tcttttttta aattctaatg
    16441 gagagactcc aattttttct ttaaatactc tgtaaaaagt ttttgtactt ccaaaaccaa
    16501 cttcttcaac caaatctaca atggatatat tgttattaag taatatccac tttgcttttt
    16561 ctaatctata ttcatttaaa aaagttataa atgtttttcc tgtatttttt ttgaaaaatt
    16621 tagtaaaata atatacacta aatcctactt cataagacac atcttctaat tttataggtt
    16681 gtttataatt tttttctaca tatttgaata tattgttcaa tctctctaat atctctttag
    16741 agtttatttc atattctact gtattttctt caatttctct aggaatctgt ctatataata
    16801 taggaattaa attatacatt ttacctttta ttgcataact atatccttct attttgtata
    16861 ggtcttcatt gtagatatct atcaatatat cgaacactga ctttcttatt tttgctgacc
    16921 aatctctact acattttttt atactactga ataaattaat taagctttct ttttcctcat
    16981 ttaataaaat taaatcatta aaaaaagata tatcaaattg aaatactaat ctttcacttc
    17041 ccggtgatgg cagtatataa tgaatatctc ctccttttat tatcactatc tcgccttttt
    17101 ttaattgcat aggcttgtca tttataaata gatttactac accttctgtt ataagtaata
    17161 tttctatttc cttatgccag tgtggtgttg ttaatacttc tccttcattt gatagactac
    17221 gaaaaggaaa ttcatgtatt aatttaggca tttctaaata tattgccata tatatcctct
    17281 cctctctagt gtctaaaaat taatttatac tatttaaaag aatacacatt ttattttaaa
    17341 aacctcaaat ttataattta tacaatacct acacttcata aaatatatct aatatttctt
    17401 tttttgtatg tgcatttaaa agtctttcac ctatattttt accacctaaa atgtaagcta
    17461 ttttagatat taatatcata tcttcattgc ctccagattg tggcatagca aacataatta
    17521 ttacctttac aggtaagcca tctatacttg gccaatctac acctttttta gatttaccta
    17581 ttactacaga ggccttcttt acatattttg tttttccatg tggcatggcc atttgataac
    17641 ctatactagt agagcctatt ttttctctat gttttaatgc ctttataaac ttacttttta
    17701 aagttatact tcctgtatcg tataatttat ctactaattc ctgtattatg ccttcttttg
    17761 tggttgattt caaatctaaa ataatgcttt cttctgttaa tatttctcta atttccattt
    17821 gttttctcca atagattatt cttaaataat attttaatat cctctttgct cttgcaatct
    17881 attatatagt ttatatagtt cttttgccta tataaatttg atatttccat taaaatattc
    17941 tttaaaaaac tttgattact aatttctaaa taaatatcaa tcgttctagt aacattattg
    18001 acattcatta tccctttatt taatttactt tgcttatgta tatatatatt taaatctttt
    18061 cctaatgaaa tagattcata tttactccct aaattcacac ctattaaact ttccatctga
    18121 gctacatcaa aattaaaata tatattatct tctaaatata ttcctaataa gtttgtatct
    18181 aagttcatac tttttttagg tttagaaagt aaagcatttt ttatattatt aatatcattt
    18241 tccattaata gtactgatac aactatatgt aatttatctt tcaaatctaa gtttacagta
    18301 gatattacaa agtctacatc atctaaattt cgcttactca actgatgcat aggaactata
    18361 tcaactatag tccattcagg aaattctctt tttaatctgg ctgcaaggag ctgagatgtt
    18421 ccatatcctg tatgacaaac tactattact cttttactac tcatatttct ttctattgcc
    18481 gcttgaaaat atgtggcaag atacgagact tcatctatac taatattctt cagattatca
    18541 tactctgtca taatatttat agtcatcata cataatccca gcacatctga aaatcgctct
    18601 tgtatctctc ctaacaacgg gttttttatt tggatatcat atcttaatct gtttaacata
    18661 ggccttacat gagatgctag acttttctgt agtaagtcat catttttgag atttatattt
    18721 aaaaatcgtg acatattctc tatcattata gatgaaactt tttcactttc acttaatcta
    18781 tctgattcat cattgtaact actattattt tcgctactaa atccagatga tactaaaaaa
    18841 atatatatgt acataatttc atctttcgtt atttttactc tgtatctatt ttctatttta
    18901 tctataagtg tagtgacatt tttatatact aactcgtcca aattatctac agaaatttct
    18961 ctttcttcct gagattctat ttgattacct tcttcgattc tctttaaaca tataagtata
    19021 tgggtaatta aatttatata gtagggctga tttatagtat atcctaaatt gtattctaat
    19081 tctgtaatta tagtttctac aaatataata gaatcaatat caaataaatt tatcaatgca
    19141 ctaaatgtag cagaatctaa tcttgttaac tcagatatat catgttgttc ataattttca
    19201 tctaataaat catccatcat tttggcaatc gatttcctta tatccacttc tttacctata
    19261 atcttagttc cttctaaagt tttattaagt tttaaattgt attcttttat ccatgcctct
    19321 atatatttaa aatcatttac tatagaagtt ttacttacat aatatttatc tgctaactga
    19381 tttattgaag ttatattatt tgaatttagt aataaatact ttaaaatctc cattcttctc
    19441 tgctctactg ataaagattt attttccttc gattgtatat ttaaactatt aattaagtct
    19501 atgttcttct ttgctaaatc ttctattaat attccatagc ctctttttat atcaattttt
    19561 atattaaaag tttctaaata tttctcaatc atcttcaaat ctttttgtaa agttttatca
    19621 gatacattta atttatcttt aaagtatttt ataggtctat atttattttc gtttagtatc
    19681 aatttaagaa attcaatttg cctcgacaca agcatactta gccctcccta cctatgttta
    19741 tatatttcta tgtttatatt aagtactatt ttaacatatt tactaactat gtaaaattac
    19801 taagatactt ctgtatcata aaagaattta tgatacacct tactaaattg atataataga
    19861 taatataatt tcaaaataaa aattaaggat atttagaagt agttaactga ttctaaatat
    19921 ccttattatt attctatata cttgttgtta ttccattaat tatttttact attatttata
    19981 atttaagcac caagtaattc aacttcacta ttttcactcc ttatagtagg ctttgttacc
    20041 cctataatca atgctgttac tactgtacca atcaatatac aagctatata tgcaactggt
    20101 gcactacatg caaatggtat tacaaatatt cccccatgtg gtgccattaa agttatatct
    20161 aaactcatac atattgcccc acctatacaa gaaccaatta tatttgctgg aatcattctt
    20221 aatgggtctg cagctgcaaa cggtattgcg ccttctgtta tgaaagatgc ccccattata
    20281 gcagttggta gagatgactt tctttcttct ttagtaaact tatttttgaa tattaacata
    20341 gccaatgata tcgctaatgg aggtaccatt cctcctacca ttaatgctgc tgatggttca
    20401 aatatattac ttgaaaacat agccaatcca aaagctgaag ctgttttatt aataggtcct
    20461 cccatatctg atgccatcat ccctgctaat attgcaccta ataatacttt attagttcca
    20521 gacatacttt gtaaccaaga ttgtaaagct tcatttaacc atgatgctgg cgtattaact
    20581 acaaagaaca ttatagctcc actcgtaaat gcaatcaaaa gtggacatat caatacagca
    20641 tttactcctt ttaatacatc tggtaaattt tctgttatct tcattactcc taaagctata
    20701 tatcctgttg caaaaccagc taccatacca cctataaaac ctgaacctcc aataactgcc
    20761 ataaaaccag ctatcatagc aggagcaaat ccttgtcttc ctgctattga tttagctata
    20821 aaaccagcaa gtatcggtat aaataactta aatgctgaat cgcctccaag ttgtccaaag
    20881 aatccagcta tagggttgta tgtttcatga gttgggtctg atgcaaatat accaaacata
    20941 aaagctatgg ctataccaat tccacctatc actacaaatg gaatcatttc agatacacca
    21001 ctcattaagt gcttataaac accctttttc tctgaccctt gaagcatttc ttttgaatct
    21061 tctaaagtct ttccacctgg tttaatttct ttagccattc cattttcagc gtttataatt
    21121 aaatttttag ctaatgaaac attcttagca tctactactt tcttttgtag cactttcttt
    21181 cctataaatc tactcagttg aacttcttta tcacaagcta ttattacgta ttcagctctt
    21241 tttatatctt ctttagtcaa cttattttct acacctatag ctccatgagt ttctatttta
    21301 acttcatatc caagttcttg acctgcttcc tctaatgctt tttttgccat aaaagtatga
    21361 gctatacctg ttggacatcc tgttatccca actataagac ctttattttg attattacta
    21421 aaatctcctg attctgcagc tttattatta aatatactta atatttcgta tggagtttct
    21481 gcacttagta gatgcttaag aaaattttct tccattagat atgtagctag tttagatata
    21541 atcttaagat gttcatctga acctgattct ggaactgcta tcataaaaaa tgacctaagt
    21601 ttttgaccat cattatctgt aatctctcta tctgttctta aatacatcat tacaggttga
    21661 tttactacat ttgacttagc atgaggtata gctattaaat tacccatatt agttgatgat
    21721 tctttttcgc gtttattaat atcagctata aacttttctt tattatttat ataatttcca
    21781 tggtacaaat gatttgccat ataattaatt acatcttttt ttgtttgtaa ttgtttatct
    21841 agtacaatac aatcgcttcg tagtatttta cctatcataa attctcccct ccttttaatt
    21901 tgttacctca taattaattt ttatttttat aaaagcactt taacttatct atagcattga
    21961 atagattcat tttaaactct ataacttctc ttgcagattt tatacatggt ggatatatag
    22021 tatctggctc atataagctt gggttttgtt ctaatagttc tctgcacttc ttataatatg
    22081 ccgacttaac atcactcgaa atatttattt tacaaactcc tagtttaact gcttgtgcta
    22141 tttcttcatc tggatttgat gaaccaccat gaagaactaa aggtatatct actacttctc
    22201 ttatttcttt taataaatct agtttaagct ctggtttaaa accttttgga tatataccat
    22261 gtgctgtacc aattgcaata gctagtgtgt ctactcctgt tttttcaaca aaatccttag
    22321 ctaattttga atctgtatat attatttcat cagtaccacc ttcacttgat gttcctgttg
    22381 ttcctattgt tccaagttct ccttctacgg acacatttaa tccttttgct atttctacta
    22441 tttccctaga tatagctaca ttctcttcat atggtaaatg tgagccatca atcattactg
    22501 atgtaaatcc acatcttatt gcccttaata tttgttcttt attttcccca tgatctaagt
    22561 gtattaccat aggtacttta ctcttatttg cttcttctat gcaactagct acaaagctat
    22621 ctcctagaaa acttagctca tttgggtgta ttgcaagtat tactggtgca tttttttcgt
    22681 tagcactctg tactactgct ttaagtattt gcccacttcc tatattaaat gctggtacag
    22741 caaattgatt ttcttgtgcc acttttagca tttccttcat atttattaac atattgtacc
    22801 tcccgatatt ttaaatttta ggttgaattt gcttcttgtt aattttgttg ttgtttatat
    22861 ttaaataata tcagtgtaat gaagatcaga aaataacaat cgttttcctt agtgaaaagg
    22921 aacttttatt atacactcta agttcctttt cactaaataa tttttagaag tctgcatcat
    22981 agttaattat atttctcata tacatcttct ctttttaagt gttttatgct ttagccttcc
    23041 tagattttat aataaacaat taagatacat taactataaa tttaaagata ctcatgcaat
    23101 agttaatgct atattagagt caaaaaaatt aaaaagatat tagctatttg gccaatacct
    23161 tttcttggat tccaatagta tatatgattt atagaaatca tactcacgat tatctaatgt
    23221 tttacttcca taaactttac ataaaacacc aaagtgacac cctccaaatt catctctagc
    23281 taataaagtg atttggtttt ctaagcagca atttataaat tagcctttgt tatcttatgt
    23341 aaatcttttt ctatctaatt taaaaattat tcctaatgct atatagcata taccaattac
    23401 taatacacca taattcatag atactcctat cttaaattct tgcatattag ttacaataga
    23461 aattaaaata ggtttattac aaacaccata aagcaaggct gacattgtat attatccaat
    23521 tgtatgaatg aatactaata tagctccttt taattaaatg atgctacata aatcatattt
    23581 atcccaattt ttaatctaac ctatttatat gtatattcct ttttaataaa aaaagatatt
    23641 gactaaatag tcaatatctt ttagttgatt taaataccca caattttaat ctaattttta
    23701 agtgtttcct taacataatc ttataaatat taaaatttat ctacctataa aatttctcca
    23761 ttaaatttta ttacatttta tcttaaaaca attataatct gaccttaatc acatgttata
    23821 ttatataaat atttttaaca aacttaatga ttaaataact atattttatt atccatctta
    23881 taaatgttta taaattttcc actattcttc ttcaataaat tcaaacaaat tttctactgt
    23941 agtatcgaat actttagcga tatccacagc taacttcaaa gaaggattat atttcccatt
    24001 ttctaagtgt acaatagtct cacgtcttac cccaaccaat ttagcaagtt cattttgcgt
    24061 cataaggagt ttttctctgt attctttaat ttttgttttc atcaatattg ccacttagtt
    24121 acatatcccc cttttatcaa agtatatata caacactaat ttagataaag actgtataaa
    24181 taaaactgca atgaggatta tacctgtatc taggtttgat atatttatat tacttgtata
    24241 aggtgttgca aagaaaatag atattattac tatagaatat atcattattt ttattgcaat
    24301 cttattaacc tttgatagta taaattcaga tgattcatca actaaatcat tatatttttt
    24361 attataaatt gaataacatc caaaaactat taaccaactc aaccctggaa gagaagcagt
    24421 gcttggacct ttaaaaatat acttagtgga taatacagct ataaaaaaat aagttattac
    24481 aagcaactcc aggataagct ttgatcttac accagtttct gatttagaca tataaaatca
    24541 ctccttaaaa attatattct ctatactctt taattttcgt ttttatcaat attatcacct
    24601 agttgcatat tccctttcta tcaaaatgta tatacaaaat taatttagat aaagattgta
    24661 taaataaaat agctaagaga attacaccta tatccaaatt tgatatatcc aaacctcttg
    24721 tataatttgc tgaaaagaaa acagctatta gcaaaataga atataacatt atttttgatg
    24781 caatatgatc aacctttaat aacataagtt ttgacgcctc gtcaactaaa tcattatatt
    24841 ttttattata catgaagtca catgcccaaa aagcgaataa aattataaaa gtaatacaaa
    24901 gatttccata tttaaaaata aactttttta ataatgagtc tataaaaaaa taggatatca
    24961 taagtaactc tgaaacaaga tttgttttaa caccaagctc tgatttagac atataaaatc
    25021 accccttaaa agttatatat ttataacacc ttatgttata aatatataac ttttccaaat
    25081 aaattgcaat agaatattga aaatattcaa taatatcttc ataaatatat tttataaaag
    25141 gttttataat aaacattaca atacagtact aaattagttt atttcatcta tcatctcaat
    25201 catatcattt actaactatt attctaatga gcatataaca ttgaaattta taattataca
    25261 acctaaatgc ctcccaatgt accctcaaaa acatcatttc ctgtaactga agtataattg
    25321 gtatatttta tcactgaaat aaaaaaacac tagtcaataa agactagtat tttcaagtat
    25381 tttatcattc tttttttaat tattggagac gaatcattag aataatgccc ataatttatc
    25441 tatatgcaaa ttctaaattt aaaataaagt ttcagataaa tttactattc tatgctatga
    25501 tacaacagaa aaaactgaaa tctatgagtg gtagcttcat ataatcctag ttcctacagt
    25561 aatcaaaact gaggtttatt ctatatgtaa ctaatgataa attttattat aggagttatt
    25621 agctctattt gtgttactat aagtagtaat tatatatatg ataatttttt aacacttttc
    25681 tgttggctat atagaaagtg gtttagaatt taaatttaaa taaaatttaa attcaccaaa
    25741 aagaaatcta tattagaaac cactactcta ttccaccaga ttgtaatttt ttgttcttta
    25801 tatcacaatg ctataccata ttaaattgaa aaataaattt taaatttatt tgttacaatt
    25861 cattaattca aaaaaatatt ttgagtcatg agttttgtaa agatttagcc atgaatttaa
    25921 tgcttctgat tcaaaaacat ctaaaagttt caatacttga aacgtaaatt ccaacggagc
    25981 aattcctgaa gccgtaacta aattttcatc actaactaca gattccgttt tataatattt
    26041 ttctccagag taatttggta ttaccatttt aagaaactct aagtcattac ttgtatgatt
    26101 tctaaaatct aatagccctt ttttagctag gcctaatgta gctccacata tggctgcaac
    26161 tatagaatct tgtattaaag cttctttaac tttttctaat attatctcat gattcatgga
    26221 taaccaagta tttccccctg gcaaaattaa taaatcctta ctttccatat taaactcatc
    26281 aactgtaatt tcaggtaaaa cttttaaccc acccattgtt ataataggat ttttatcaat
    26341 tcctacagta attactttta gtggttttaa tcctttttta aaatatcttc ctgtatttaa
    26401 ttcagcagtt aaatatgcca cttcccaatc tgacatagta tcaaatacat acatatatac
    26461 ttttctattt ttcatctttt ttactcctta tgtaattaat ttatatatct aattataaaa
    26521 taacttaact gacatattca gtcagttaag ctattaaatt tgataataat caattaattc
    26581 tagtaaatct tcaattattt tcttcctaag gcttagtggt tcaattactt gtattgtctt
    26641 tctataaggt aaaagtatat ttggtatgta cttgcatatt acttcctctt caagcataaa
    26701 tattatttta ttaggtgttc tttctttcaa gtagtgccct aaaaaccaat gttgacttaa
    26761 actatctaaa gaatctatac tcccttctac aactaattga attatatttt gttcatcttt
    26821 tatttcaggt ataattcctt ttataaaaaa ttcacttgct gaaaattctg tcggtctgtt
    26881 aaatgtattt gatgtttcta tgatttcact aatcctatcc actctgaaac tacgtacctc
    26941 atttctcata ttacaaaatg caactacgta ccaattatta ttccagtgaa caattccata
    27001 tggatttata attctatatt ttgattttgc tttacgacct gcatggtagt tgatttctac
    27061 agatagctcc tttaatatac tattctccaa ttttttaagt actgattcta tagacacttt
    27121 cccaattggt tttattactt caagggctct taagtggttt gttaaaatat cttcttgttt
    27181 ttgatttgaa tacattttta actttaatat cgatttatct aatgcttcgt ctaagaagta
    27241 tccttctttt ttagcaaata gagctgcatg aagtagagat ttttgctctt ctatatcaaa
    27301 aaaaagaggt gctttagtaa aattatttaa aaggctatac ccaccattat gacctgtatc
    27361 tgaaattata ggtactccac tcgcagaaag tacatcaata tatcggtaca ctgttcttat
    27421 atttatttct aatttttcag ctatctgttt tgctgtaatt tttttgtcag agtttaatat
    27481 ccacagtata gacatcatat tgtcaatttt agccatgtag tttcacctct ttctatttgt
    27541 tatataaagt tattatataa cttctgatcg attttttaca aaaaaacatt agtaaactgc
    27601 taataattta tactaagatt tatttcaaat atttatagag agtctttttc tatagttaag
    27661 ttatccatta aattccatag tagtgtatct acttcaattg atatattttc aactacactt
    27721 ctcgttatat atcaattttc ttttttaaag attttacaac tgatatttag ttcaagattt
    27781 atatatattc tttttcaaaa acctttcagt ctcaaattaa aacttttttg ttttaatttc
    27841 ttcaagatat agaaaaagtc ttatcctaat ttatttaagc taaaattctt atattttaaa
    27901 tttttcttta aaactaaaat atttattatc atcttcagca acaatataaa tctactaatt
    27961 aaatacctaa tatttattca tatttttcta aacataatta ctaaaattga attaatgata
    28021 tcaattccat taatctcttt taataaaaaa ttctcttttc tatatgaaaa ttatttcaaa
    28081 actttaaagt taaatacaaa aatgactata aataggtttt tatttacaca aatctatcta
    28141 tagtcactat agtttatcca ataaaataat aaaataaata tgtacacaat aaatgttatt
    28201 tacgtcttaa gtatttattt gttagatttt taattaaaaa aaacaagcta atgaacatta
    28261 atgctaaatc tagcattata ttgctttgat ctcctgtttg tacattttga cctacattac
    28321 tatctaaact ttcatctgta tctatattta tatctggttt tccattccca tctgtatcta
    28381 tatttatatc cggctttcca tctccatcta tatctatatt tacatccggc tttccatctc
    28441 catctatatc tatatttaca tctggttttc catctccatc tgtatctata tttatatctg
    28501 gttttccatc tccatctgtg tctatattta tattcggttt tccatcccca tctgtatcta
    28561 tatctatatc tatatctggt ttgctatttc ctccattatc tgggtctggt ttactatttc
    28621 caccgttatc tggatccggt ttgttatttc ctccattatc tggatctggt ttaccattgc
    28681 caccgttatc tggatctggt ttgctatttc ctccattacc tgaatccggt ttgctatttc
    28741 ctccattacc tgaatctggt ttgctatttc ctccattacc tgaatctggt ttgctatttc
    28801 ctccattatc tggatccggc ttgctatttc ctccattatc tggatccggc ttgctatttc
    28861 ctccattatc tggatctggc ttatttagat ttggattacc tgtatcataa cctcctgagc
    28921 cagtatctac atttttatca ggcttccaat aatcatctac tccatcatta tctgtatcta
    28981 ttgctggacg attataatct gtatcagggt ttccatctcc attggtatct atatttttat
    29041 caggtttcca aataccatct ccatttccac cttctgtact aggcttccat tcacctgtat
    29101 tatcagtatc tatgttaata tctggcttcc aatcaccact cgtatctata ttgatatctg
    29161 gccttccatc accatcagtg tctatattta tatccggtat tccatcccca tctacatcta
    29221 catttgtcac atctaacttt aacttctttt catcctcact accttcaatg taatttatat
    29281 catctccaat atattttaca gtaatagttt gttcagtagt aaaaatatga tgattgctat
    29341 ctaaaggtct ccattcaata gatgcagtac tataattatg actctcacta cccttattat
    29401 gagtttttaa ttctactgga tctttatatt cctttccatt aatatagaat tgtacgtaac
    29461 ctcttggaga ggcacaatct ggtccttctt tcttatctgg tgaaatagta acatttaatg
    29521 taaacgtatc tgttggttta aaaacatcag ttttagcttt agactcttct acaactaatg
    29581 aagtttctgt atcagcagga ataatttctg ccttataata tgctctatgc ccccaataag
    29641 cttcattaaa aggatataca tttgaaaact gtgttgatgt aatgcttaat tgatattttc
    29701 cagcatcaac ttgctttgta aggtcatcac ttcctaaatt tgtatctggt tccattgttt
    29761 cctcatttaa acgttgagaa ctaatagtca taaatttttt atctgtgagt ttttcacctt
    29821 taggagtaat tattggaata cccccatctt ttaatatcca atctaaaaat gatttttcta
    29881 catcttcttc aaatggtaat ccatcatatc ttttaataat caaatatggt ggagtatcat
    29941 caatagtaaa ttcttcatat tgctttaaaa attgagaacc tgaacctata tctttaacat
    30001 aaaaatcatc tggttttata tttcctccag taattttatc tataacaact aaattaacag
    30061 atacttcaga tcccttaaat tgttcagaaa accataagta aagaacccct tgatcatctg
    30121 tataactagg tgctccataa ggataaattt ttccatcaat tagcatttta aaatcatcaa
    30181 ctaatgtagt actaacttta tcttgtccta aatactttaa agatatttta ttcataaaaa
    30241 cttttgtttt cttttctaaa tcaccgtatg caactgctcc acctaaactt ttgaatgttg
    30301 ttgcttttaa tgaaccacct gttactataa catctcccgt tgtagcactt aggtcaaaaa
    30361 tccaatctcc cactcctgtc atataaggta aaatcgttcc tccagttaca agtatacgat
    30421 atcctctatt tgttcctgga ttaacacatc catccccaaa tgcactacca tgtgcacctc
    30481 catatgaata ggaaagtcca ccattaattg taatattccc actataacca gaacctgtgc
    30541 taggatctac tactgaggga cttaatgcat tctttgttgt tgtatagtat cctccaccta
    30601 ttccagctcc atggtatgca cctttagcag ttatagtacc accattgatt gtgatatctc
    30661 caccactacc attaccgcct ccacctattc cagctccata tcctgtatta cgactcgatt
    30721 cttgacctat agcagttata gcaccaccat taataataat atttcctcca ctttcagtat
    30781 ttccaccgcc aatacctgca gaataataat ttccaacaac ttttaaactt cctctattat
    30841 tactatctag tagtgtaagg cgatctcctt tttttaactt gtctccattt tctagagtta
    30901 catctctagg aatttttcca ccctcaggaa ctataaactc gccttcaata tctctattta
    30961 caacagaatc atcaataatt agagtagtac cttttcctgc tctcatacct ggataatata
    31021 catcacctga ctctagcttg ttttcactac catcttgtaa tataacatgt gcatatgcac
    31081 caccatcttt atctggtgtt aaagtaaatg ggctattaga tgcagtttta atatttactc
    31141 catcaaatat taattcagct tttacatctt taggtataac aatcctatgt gttgttggag
    31201 tatttggatt attattttga attgtcattt gttttccact aagaatagtt aaaacgccac
    31261 ttgcaaattt aaaatcgaca tttatttctc caccactaat tttaaagtct cctacagatg
    31321 taggatcttc tgcagtggct tcttccacaa ctaatgcatt catatctcct tctgcatttc
    31381 ctgcattaga atcttcttct gcatttcctg cattagcatc tccttctgca tttcctgcat
    31441 tagcatcttc ttctgcattt cctgcattag catctcctcc tgcatttcct gcattagcat
    31501 ctccttctgg atttcctgca ttagtatctc ctcctgcatt tcctgcatta gcatcccctc
    31561 ctgcatttcc tgcattagca tcccctcctg catttcctgc attagcatcc ccttctgcat
    31621 ttcctgcatt agcatcccct tctgcatttc ctgcattagc atcccctcct gcatttcctg
    31681 cattagtatc tccttctgca tttcctgcat tagtactttc ttctatagta tctgcgaaag
    31741 tatttgacgc attaaatgat gctactgatc caagtcccat tgagatactt aaaatcattg
    31801 atagtgcttt ctttttacat ttttgttgca taaattcccc ctccccttaa caatttttaa
    31861 tatacactgt atacatcctt atatacactc taataattct taatatacac tgtatacatc
    31921 cttatataca ctctaataat ttttaatata tacttaaaac ttatatttgt caatgaatat
    31981 acagtttttt tcaaccttat atattataag tattcattat ttgctaaata actacaataa
    32041 aaattttaat tatataaaat ttatttaatc ttttatataa taatacaagg ggtaattaat
    32101 tgaaaaaact agtaaaaata ttaataaata ttatttgtat tattacgcta actttctcta
    32161 gcctttcgat ttacataaaa ttatctgaat ataaaaagct gatgaagtat atacggaact
    32221 cagagaaaac actatcaata atagcaaaca tcaagaactt tatgataaaa ataatgatta
    32281 tagattctgg cttaaaataa acaacgtaaa tatagactat cctgtagtac aaggatataa
    32341 caatgatttc tacctaactc atgattttta taaaaattat cttcctttag gtagtatttt
    32401 catggattat agaaataatt ttgaaaatga taagagttta atagtctatg gtcattatat
    32461 gaaaaataaa actatgtttg gtcagctaga aaactatact gatgaagtat ttttcaaaga
    32521 aaataattta gtagaaataa attataaagt acaaacttat acttatgaaa ttttttcagt
    32581 atatactgct gacttaatta acagagatta tttaagtata cactttaata ataatgatga
    32641 gtttaaatat tctttgaatt atataaccta aaaatcagta cacaaatctg atataaaggt
    32701 agatatttca gataaaatta taactttgta tacttgtaaa tatgaattta aagatgctct
    32761 tactatagtt catgctaaat taatttcaaa aaagagacct ataagtaggt ttgtgtaaat
    32821 gcagacttat ctacagtctt ttttgaacgt aaaattggta agtatagaat aatattcata
    32881 ttaaactttt gtaggcaaag aaatgaaaaa tcaaagagaa ataattatta cagatttaga
    32941 ttaccaagct gaattaagag agtgtaaaac tatggaggat gtagttggtg aagataatat
    33001 ataatagttt aacttataaa ttatcttggt gatattaatg aagtttcaaa gtatatatta
    33061 tttattgata taaataaaat taaatctgtt tctaatagat gtacctttgt ttggagacaa
    33121 actattgaag aaatataact aaaatgttga agtagctacc tgactttatt ttgaaatgcg
    33181 aacaagattt tggcattaag ataatttaga aagaatcact ggtacacaag gatgtgaact
    33241 tagaatgaat agaagtattc aggcataagg agctttcacc caaataaaac atagtatgaa
    33301 ctttaaaaga attctaatca aaggcaatca aaatattctt tcagagttta tacctgtagt
    33361 gttagcctat agtatttcta agtttcacaa ataagataat cattaataaa tgtagtatgt
    33421 atattcatcc tctcaaaaat attttttaat cttacacttt gtaaattatt ctattttaaa
    33481 attgtatttt tataccttta tttcttatga ccgttttcaa gctcaaattt tgcataaata
    33541 taaattaatg aaaagcaagt aaaaaaaaac tgtcgcacag caatttaaaa ttactcattc
    33601 gacaatcctt ttttcgtgga tttaaatagt ggagaagaat cacaagaata atacccacga
    33661 ttaaaccttt atacaataca ttttatatga ctttaccatc actaatagtt attatacaat
    33721 cagccatctt agctatttca tcattatgag ttatcataac caacgtctgc ttgtattcat
    33781 ttacacaata ctttagtaaa ttcatcacct cattagttgt tttactgtct aaatttccag
    33841 taggttcatc tgcaaaaatt attgatggct tattggcaag tgatcttgct attgcaactc
    33901 tttgttgttg accacctgat aattcattag gaaatttatt aatctgactt tctaatccta
    33961 acttagttat taaatcatta atataattat tatctatctt tcctttagca attaaaatag
    34021 gaagaactat attatcataa acattgataa caggtattag attatagttt tggaatataa
    34081 acccaaattc tttacttcta agattagata gcttttcatc acttaaagta tataaatcta
    34141 aattatccat aaatacatta cctaaagttg gtttatcaag ccctgccata cagtgaagta
    34201 atgtgctttt tccagaacca ctttgtccaa ttattgcact aaatttatgg ggttctatct
    34261 ctaaagtaat tccatcaaca gcctttattt cattttctcc ttttccatat atttttttaa
    34321 tatctataac ttttaacatc ttcatacatt tacctcccaa attattcatt ctcttttata
    34381 ccttcaataa tattcatact ttcaaaatct ctattactta caactactgc tattaaacat
    34441 acaaatacag atatagcaaa gaatagtaaa gattccttaa ttgggaatgt aaaagacata
    34501 aaattctcta ttccatagtt tatatacgca tcattattcc aatttgtaaa tttaactaga
    34561 tttataaatg atggaatcat agctattata aagctaaaaa ctgcatatgc taatgcttca
    34621 tatataagca tttttttcat atttttaaga ctaacaccta atgctctaag cgttgaaatt
    34681 tctttttttc taattagtag atttgttctt atagtacaga aaatattaat tgatgctatt
    34741 attaaaacta gtgcaattat tgctatttgt gatttaatgt aacttttata tatactttct
    34801 gacatttcat gataacttaa tctactatta aatagagacc ctggtatact tcttgaaatt
    34861 ttctgtatct cattattaac aatctcatca tatggatttt ctaaatttat gcctaattga
    34921 gtgtattttt gttctcctgt tatgttttta gagtgaatat tacttgttat aatttctaga
    34981 tctggcataa aatcgccatc tcccatagca atccattcat cctttaaaat tacagccact
    35041 cttaccttca tctctttata aacaattgta ttattttctt caacaggaat ttttacagtt
    35101 attatgtctc ctatatttaa ttctttgaat ataggcttta tagtatgatc atcaactata
    35161 tcataaaaat aattatatac tgctacattt ggatatccat cagtgtcctt tttaatatca
    35221 tctaagctac cttcttcaac aaagtcattt aacttttcat ctatataatc atcatcataa
    35281 agctttaaaa ctaatttatc ttccattatc tctttttttt ctactccatt ataggttgta
    35341 aattctttgt ttatatcctt attattaaaa gtaaacattc catttgttat ttgaatttta
    35401 tgtatacttt taacaccctt aattttttct atattctcta catcactatc cgtgtatttt
    35461 gatatttgcg ggtctgcatt tactccaaat tgcattgtta tattatatct attttgcata
    35521 tcttcaattt tactgttgac ctcttcttgc atacttgaga atgtagtaat gaatatatat
    35581 cctcctaaag caatagacaa catagatata gcagctctaa ccttatttct tccaatattt
    35641 ttaagtccca taaatccata aaatccaaat attttgctta ctagtctgtc tattccaagt
    35701 ctacttctgt gatttttaat tttgtctgta tttattattg attcaatagg tgatatcttg
    35761 ccgattttaa aagttggtat aatacaagat ataaaaacag aaattattcc aaccaatata
    35821 gcttttataa ctatttcatt atttatatat aatttagggt taagaccagc ttcactgtat
    35881 aaagcttcgt tataattact aattcctata tatgaatatg taaccccagc tactaaccca
    35941 agtagtatac ctattattgt tataattaat gcttgataga ttatcataca ccttacgttt
    36001 cttttctttg cacccatcag tctaaacagt cccatttctt ttactgattg atttagtgta
    36061 atattgaaaa tattaaatat gaaaattata gatactgtag ttattaaaac atttctttta
    36121 aaaacattcg gatcactctt atcatcttct acataacgaa gttcccttac aagaggtaca
    36181 tttggtagaa agcttttttg tcctaactta tattttttca taagataatc acattcacct
    36241 tcaatatttc tccatccact tttaaaactt aatatactat tataactaat cgcatcatta
    36301 ggtataatgt tgtttgtttc atcattgcca taagttactg cttcgtattg ccaaaccaca
    36361 tcatagtacc cttttggttt ttccataact cctactattt taaattcttt atttatagaa
    36421 aataattgat tacttccgtt agtatcttta tagttctttt ttattgttaa atttaatgta
    36481 gatcctactc cttcacttaa attcattgct tctagtgctt ttttctctaa tactatttca
    36541 ttgttgtttt taggtagtct accttctatt attttgttgt atctactttt tagatactct
    36601 tcgtttgatg aagttaatat aaatgagttt ccttttttat ctgaaatacg tcctagattt
    36661 tgtaccgaat taccctttga tactttttca tcagtttcta attttttagc atcatcaagt
    36721 gtcaaatcac taaactctac atggtatcca ctgtaaagtt catgtattgc tactacattg
    36781 ttttcatttt gtgaatcttt tataacacta ggtccaaata tcaacataac acctaacata
    36841 actcctatta ttaaaagtaa tgttctaagt ttatttttct ttaaatatgc tagtgacatt
    36901 tttaagtaaa tccccatata atcctcctat tttactataa attatttatc caactcatct
    36961 gttaagtaga ttggtggata ttttaaatct tttaattctt cattattttt tgaagcttac
    37021 taccatcttc ctcatgataa acttgtagta tcaccttatt tacatgtagt gcataataat
    37081 caccactata aaaatattgg tattcataac ctgaataatt tttgtaaaat gatttat
//
LOCUS       DAFAZV010000042        37001 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFAZV010000042 DAFAZV010000000
VERSION     DAFAZV010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 37001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37001
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.042"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..275)
                     /locus_tag="KOU88_002834"
     CDS             complement(<1..275)
                     /locus_tag="KOU88_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212701.1"
                     /translation="MDRANRIIYDQTGKILLQTGEATGDILEHDTITELHYIDVEYGS
                     IDYTRNRIIGINIETKEPILEEIPTFISDEEKRIQELENQLLIAENE"
     gene            complement(292..1983)
                     /locus_tag="KOU88_002835"
     CDS             complement(292..1983)
                     /locus_tag="KOU88_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212702.1"
                     /translation="MAIVYEFNYTGAEQSVVLPPGKYKFECFGACGGNYYDFVQCAKG
                     GYTAGSLILKENTTLHVYVGQSGYCKGVNGIETCRSGFNGAGGITTYKSTSDGYYSLA
                     GGGATDIRLIGGNWDNLQSLLSRIIVAGGGGGGSGNSHDSIGHGGGTKGKDGISIANK
                     YFAGGGSQFQGGLTFNSLYNGSFGVSGAGDGISGVGGGGGWYCGAGSFYAEFGGGGSG
                     YILTKDSYKPANYSPSSKYYFSDINSVVGGNTTKQDGYAKITLLQALPFLTISSYNST
                     QATFKADHTDPTLLTKIEYFIDDVLKETITTDLTTEKIINYTLEDNALHTLKIVVTDS
                     ANATAEKVVSISKGIAPLPAGSTTDEVTSKWIEIKDTFKSGKTSIINTLALKNIEASL
                     NNTLVELSEKIKTSFDSSDASVQDLMNQLTQANNTISQLNSKYKVASGNSVVNYCTNT
                     KGFYFNSDYLFLFPGAIQINGLNFVPNIFFTTFELIDDGYFHKYFVFACRGIFTQDFV
                     ITAHYYRLTSYLQDFKVGGEVLKLNERDVYMDNRGIQLPCSRQGSSFKWQAIKFI"
     gene            complement(2000..2881)
                     /locus_tag="KOU88_002836"
     CDS             complement(2000..2881)
                     /locus_tag="KOU88_002836"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212703.1"
                     /translation="MEKSFVFNSVNGDRRYKAEDFREYFASFIGNGVFPNPSSNLQVV
                     DNNNMTITVKKGKGWINGAIYINTDDLVINIDPADGILNRIDRVVLRFDTLNRNIKLA
                     VKKCTFNSSPVATELQRDADAYELGLADIYIRAGAISITQSSITDLRLDKNLCGIVKG
                     TIEEIDTTTLLAQLNTWKDEEISNFNVWRENQENKQEDWYNTTTTNFVSEFNIWFESI
                     KDILDEDAAGNLLNEINKVKEELAKIETTAEKTSYNNATSNLTATNVQGAIDEIVAKI
                     ENFNEINISIQNDMLPI"
     gene            complement(2881..3960)
                     /locus_tag="KOU88_002837"
     CDS             complement(2881..3960)
                     /locus_tag="KOU88_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siphovirus ReqiPepy6 Gp37-like family protein"
                     /protein_id="HBK3212704.1"
                     /translation="MQQSIRILDKNINLIAEIDNYEELQIIKKFHKVGEFSLKINANK
                     NHVDKLVKNNIILLGKNYNKVCLILHREFMYTETGEKSDILSVKGVDLKGLLNRRLII
                     PDTGEAFESHEGTQEEIIKAFVNNNCVDPSNPKRVIDNLIISENKNLGSADMWRSSYE
                     NLSDKIQEISEFCGLGWEVVLDANKKKFIFDVITGKDLTINQTENPPVIFRSDFNNIR
                     ARHFTESIINSKNVVYAGAREDATKLVISTGEVEGFERNEVFADVSENTISILQKEGE
                     IKLKEYEELKSFELEIDPKNTFMYEKDYKLGDIVTVQDRKLKVTMDTRIVEVQESYSK
                     NGMKLKITFGSSIPTLFSKIKRMVK"
     gene            complement(3962..4828)
                     /locus_tag="KOU88_002838"
     CDS             complement(3962..4828)
                     /locus_tag="KOU88_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015957549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HBK3212705.1"
                     /translation="MQKLICRNSKGQEVKLGNSRPFLLEKIENGANTSANISVSNNLG
                     DGVSIDDISIKERLLPISAAIYAKNKEDLELKRAYLTSLFNPKLGEMEFIYTNNALTK
                     RVKGVVQDITFQTPVRLMQKFLIQLLTPSPFWMDEFVLKEEVALWVGDFEFTLEISNE
                     GIEMGHRVSNLICNVVNNGDVECGMKIQFKALATVDNPSLFNVNTREYIKINRTLEAG
                     DLLEITTEFANKRIELVKSNYERINVFNWIDLDSEFLQLEVGDNLFRYDADVGIDNLE
                     MSIYYNPLYLGV"
     gene            complement(4861..10062)
                     /locus_tag="KOU88_002839"
     CDS             complement(4861..10062)
                     /locus_tag="KOU88_002839"
                     /inference="COORDINATES: protein motif:HMM:TIGR01760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBK3212706.1"
                     /translation="MAEDVGELVVRVAMENSSFQQGVNNLNRQMKLIRSEFKNSGAGV
                     KNFGTSLDGLKSKQQMLSSTIQQQTKVVEAYKNKLNESKTTLSNTAQKQVELKEKVNQ
                     AKSAYEQSKTTLGENAEETKRLKSELDSLEQEYAKNEEKIRSNSAAVDNWSIRVNNAE
                     SRLSEMRSELDDTTERINQQENKWNQLATKMTEIGNKFSSVGKQMQDVGKKMAMSITA
                     PVLAVGAAASKLGMDFEASMSNVQGLSGATADEMVQLEKAAREAGASTSKTAKDAADA
                     LGYMALAGWDAKTSMEALMPVLRLSEAGNLDLARTSDLVTDSMSSLGLSVKELPTYLD
                     QVAKTAASSNTNIDALMEAMIVSGGTFKNLNVPLSEANALLGILANRGLKGSEAGNSL
                     NSIMINLTSGAGQAGVAMKELGLSAFDSNSKFKGMANVLMELKEKTKDMTEEQRTMYL
                     SMIGGKTQISTLQALLSGVGEEYSELEKKVGNSTGALDKMAKTMQNNNKGSITALISA
                     VQELGLKIYDVLKPSIAQVVSWFQNLTNKLNEMKPATVETIVKIAGLAAALGPVLLIG
                     GKIVSMIGGVIGAFGTFSAAMAVATTGAAAATPAVGALAAILGALSSPAAIAVAGITA
                     LGISVATVAKDMSKDAIEPINRFGKNISESTKEAVGAFMDLEEKTTVSLNQLMWSGET
                     VSEKMKQTIVSNFTEMSNQIVAKLQESKEQGIQSLQEMFATSKNLSDKEKEELIKNTE
                     EAYSSKEEKIKKSNEKVNQIMTKASQEHRALTKEESAEINQIKTDMLNTAVDTMSKSE
                     AEQAAIMERMKANHVDLSAKEAAEVVKNSIKKKDESIKAANEEYNERLKIAAQLRAEG
                     GVENEKLADKVVEEATRQKDESINKAKEMHQGVVAEAQKQAENQANKVDWTTGEIKSK
                     WQVLNDTVKGKMQEWDDIAGSWVESLKEKISTGWTNLKENTALLWDSIKLSVTTKWTE
                     IKESIGLKIEEIKQSISEKWESIKLFFTTTWENIKMIFGNAWDAIKQQVEEKFAPFIE
                     RLKIIFDGIKEFFRSTWEVIKNIVLGAVLLILDVVTGNFDKLKTDALQIWENIKQGLS
                     NTWESIREVFNNALAAIGDLLSSMWESMKSTAITIWESITQTLSGIWENIKSTCSTAW
                     EGLKTICSNTWENIKSTLANAWESMKTAVTTKLGEIKNNIVTTWNNVITFFKTLPAKL
                     KQAAIDMFTRLREGIDSKKQDAVNASQKVGTDVVNKIKEFPSKFLQVGKDFVSGLANG
                     ISGFAYKVVDEAKKLGQKAADAVRKVLGIHSPSRVMAEIGKFVDEGLAQGIANNSDSV
                     KKATEKITKIIEEETKKATKACEEDIKLFNKQIDELSKQEKAALKKVKGDAKDALKEE
                     YAAKKEKIKEAIALRKEQKEKEVEQLKEIANSAKEQLNKELQDRQEFVKKVDDLTKAI
                     VDALKEKYKQEYEAQQASIKKELDALDKWKEESIDRINSVYDAKIKAIDNELEAFEKA
                     EKEKDRLEQDKEELNKIEEIKTAIKFEHDDTNKEQLQKELEKVLAERKKRIEQQEIED
                     KKEALKKRKEELEEKKKDEIENINQIYESEKEYYNKRLEDAKKFYDERIKESKLQAEA
                     EKLIMDKNQKEIVALLNSYSDAYKNAGQTLGEKLLEGFKPAINEIKNLIDSITREINN
                     ARNEALSLNSDIRKGNSAANSNSGRREATYNNNSRTANYNVNVNSTDSNTAREIERTI
                     RSLAFSL"
     gene            complement(10132..10347)
                     /locus_tag="KOU88_002840"
     CDS             complement(10132..10347)
                     /locus_tag="KOU88_002840"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212707.1"
                     /translation="MCKYCEVEESEAAFKRGKTNRGELITCDCDIEMWIEKESNEYFL
                     NSECWCGYYSESFEPINFCPFCGRKLI"
     gene            complement(10599..10886)
                     /locus_tag="KOU88_002841"
     CDS             complement(10599..10886)
                     /locus_tag="KOU88_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212708.1"
                     /translation="MEIKLTINEEEKIFKAPPIPLRKLDKVFTLTDKIEDGLNSTELF
                     RELLDFTVDIYGEQFSKDELLDGFYPAGDFINKALEDLSKVSGGFEEKVKN"
     gene            complement(10901..11497)
                     /locus_tag="KOU88_002842"
     CDS             complement(10901..11497)
                     /locus_tag="KOU88_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3212709.1"
                     /translation="MAIIGLRNYRIVKLLTDTEETLEYDTKITRLTGAKSVKISPKVD
                     SAENYGDDQLLETASAMGAIEVEIEVADLTLEERALILGYQYKDGVLIEDKNFNPPNL
                     AFGFESPKSQNGSRMVWLTKGVCEPFEEEAKTKEDKIEFQSQKIKLKFMPRIHDGRHK
                     ITADTDVENAPTDAQFFTTDFLKTGVKPTTPAKANLNK"
     gene            complement(11485..11835)
                     /locus_tag="KOU88_002843"
     CDS             complement(11485..11835)
                     /locus_tag="KOU88_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212710.1"
                     /translation="MININDLVIETLKPLKIPVSFQRYNGEEKTYITFFSYLEQNFYA
                     NDEVIGTEHYIQIDLFSKNKMSYINKEIERLLKKNNFIKRSIHEIKESDYSYHAVFRF
                     LFLQKKRRIKKWLL"
     gene            complement(11835..12278)
                     /locus_tag="KOU88_002844"
     CDS             complement(11835..12278)
                     /locus_tag="KOU88_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK3212711.1"
                     /translation="MSVEITTEGFDAILSKIESMGKTGDKLLNEAVKAGGNVILQDAL
                     PRVSKRSGKLKDGLKVSGVKKKGGTKYVLVGITKEDNSEIFYGKFLEFGASAHKIPIK
                     KGKKKGRVVNHPGTSSKPFLAPAYESKKDEAKNVMKEILKRGLGL"
     gene            complement(12279..12605)
                     /locus_tag="KOU88_002845"
     CDS             complement(12279..12605)
                     /locus_tag="KOU88_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212712.1"
                     /translation="MHSKIVTILKKLNLGIGFQEYDNFSNDEEYIIFFIENEYDANFS
                     DNENKSIVYSIKIEYWYKSLKNINKYISIKDIFKKENFIFLNSSDFIENEYYCKELKF
                     KYEEVV"
     gene            complement(12625..13275)
                     /locus_tag="KOU88_002846"
     CDS             complement(12625..13275)
                     /locus_tag="KOU88_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HBK3212713.1"
                     /translation="MKKIKFNNFNDGIVEFGEYKESYDIEGNALDEKEFIVSGKLFYS
                     NEYIREQDKLKFDDTGLKVSIKLKVPYMRLIKTSDVIKLNNEFYSIVKLDISNDKTSV
                     YLYLTELVDVLDKHISIFIKERKNVLEDVTIKFYKKIWACVEDLNSKELIENNSIKTS
                     TNKKFKIRYIEELDLSIKQNAITNFVIKYKDKFYNITQILNLEEENKILEITAESK"
     gene            complement(13278..13565)
                     /locus_tag="KOU88_002847"
     CDS             complement(13278..13565)
                     /locus_tag="KOU88_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212714.1"
                     /translation="MENENIKSVVEEVKEYLNITWIEEDAKIEKMVVRGIDYFENEIA
                     GIALDFKDNFNRELLFNYCRYVRNNAIEYFEENFSKELLRLQIKSAANEVI"
     gene            complement(13575..14741)
                     /locus_tag="KOU88_002848"
     CDS             complement(13575..14741)
                     /locus_tag="KOU88_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBK3212715.1"
                     /translation="MAIKNLDEATNVELRADLMEAIKGNDEEKITTAFLRMAEDIQEN
                     LLKEARSIANIESADRAILDKRGMPQLTSEERVYYSKVIEKRGFTNLEITMPRTVFDR
                     VFDDLEQNHPLLSAITFENTTGVTEWIIRKTNAEAAWWGRLDDTIKKELEHGFDKINT
                     EAYKLSAYLPVAKAMLDLGAEWLDRYVRVVLTESISLGLEMGIVAGTGKDQPKGMIKD
                     LKGAVVEGVFPDKTAKPLADFKPITLGKEIMAPLTNNGKRAVPSVIMLVNPVDYWAKI
                     FAATTMLTSNGTYVYGVLPIPGNIIQSVAVPKGKLIAGMAKDYFMGVASSGKIEYSDE
                     YKFLEDERTYLVKQYATGAPKDNDSFLVFDIENLDTTLATEINSNTKTSAARAK"
     gene            complement(14744..15379)
                     /locus_tag="KOU88_002849"
     CDS             complement(14744..15379)
                     /locus_tag="KOU88_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBK3212716.1"
                     /translation="MEMEKRTVSLEIRDSNLESRKISGYAAVFSDDYTKLQDRWGDTF
                     YEKISRGAFLKTLADNTRDKFMLINHDWNKVVGRTNSNLILEEDEHGLRFEVDIPATT
                     DGNDLLENVRLGLIKGCSFGFNIVNSKTRWDDDWTFYRDITEVELFEITATPIPAYND
                     TEINCRSDISIKELRESQKEETKQNDNKDNIEKRNVDLVSAFFNAFNRGGK"
     gene            complement(15336..16523)
                     /locus_tag="KOU88_002850"
     CDS             complement(15336..16523)
                     /locus_tag="KOU88_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3212717.1"
                     /translation="MNFKNFISNFLFKDKMSGADGEYFKKLEATIFYKEFALKSCISI
                     IANALVLSEFQTFKNGKSIKEKNYYLFNIEPNQNQNATEFWQEVITRLVYDNECLVIQ
                     ENEQLFVAESFSVDKYVFYEDIYKDVTIRNYKLDRSFRESDVLYFKLNVESIKTVIDY
                     LYNDYKDLLSSAMKGYKKNNSEKGVLEIDTNYPQTKEAQERLNDLMSNKFKRYFESDN
                     AVLPLSNGLKYTENTKASSIKDSRDIRAIIDDVMDFVCAAFHVPAGLVKGNVAGVEGI
                     TDNFLNFSVNPVAKLITNELTRKMYGRDNFFEKSYVKVDTQKIANMGLEKISKASDLL
                     FRIGVNSINDNLEMLGREKINESWADEHYVTKNYQSILNPDLKGGANNGNGEKNGVAG
                     NKG"
     gene            complement(16539..18167)
                     /locus_tag="KOU88_002851"
     CDS             complement(16539..18167)
                     /locus_tag="KOU88_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBK3212718.1"
                     /translation="MILNYKYNKYIDEYFSLADKGEIVLCKEMKLAVKKIKKDLKKPN
                     IYIDHEKVEKAIEYMEKYFYKMYAWEKFVVALVVGCFEGDELLYDEIFIMMGRGNGKN
                     GFISQLANYLQTHLHGVKNYGIDIVAMSEEQAKTSFDDVYNMLSEHPAICKKFFNRTK
                     EVITFKKTNSYLKFRTNNAKSKDGLRPGCIIFDEVHAYENYDNIKVFTSALGKVKNPR
                     IFYITTDGNVRGGVLDDFKEEAKQILNEEIKNSKMLPLIFKLDSIEEMEDVNLLEKAN
                     PSIKYNSDLRTQILKDIDKAKNRPQMMIELLTKRFNLPAEDLATVVAEWDDIVATNEE
                     LPDLKGFSCIGGLDFSSIRDFTSVVLLFKKDKKRYIMHHTFICYKSLEITNFKFDIEL
                     AKQKGLCTIIYDETIKAEYIADWFIEKAEDYNILKICCDSYRAAHVKEEFTNKGLPIE
                     EVRNGSITHAKIAPLVEQIFAERTIKWGDDMMMRWYTNNVYVDTDKKGNKTFLKIEPI
                     KRKTDGFFAFLHALSKDDELMQESTIKFYDCYTY"
     gene            complement(18151..18657)
                     /locus_tag="KOU88_002852"
     CDS             complement(18151..18657)
                     /locus_tag="KOU88_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012720579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HBK3212719.1"
                     /translation="MDDNEELEIRRDVQNDYVLGMTYKEMSAKYNIPENTLKSWRKRG
                     GWTRNCTPKKGCVKNGLQESGNNLKNSIRKDLLRQIKENNMTEEYFKDLVEDYLKMWD
                     IKNELIEDVKTRGVQVKYKNGQNQWGYKKNDSVSELIKYNAQMLSLLDKLGIKATPKV
                     LGDDDIEL"
     gene            complement(18829..19161)
                     /locus_tag="KOU88_002853"
     CDS             complement(18829..19161)
                     /locus_tag="KOU88_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012720777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBK3212720.1"
                     /translation="MSYKHITLDRLKELILIDRLDIFYRSTDWRKLRKKAIERDNYEC
                     QVCKKKKKVSKAECVHHIREIKEYPEGALKLNNLTSLCNLCHNEIHEKILKINQEKKK
                     KFFSDERW"
     gene            complement(19151..19423)
                     /locus_tag="KOU88_002854"
     CDS             complement(19151..19423)
                     /locus_tag="KOU88_002854"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212721.1"
                     /translation="MNKYDRFKCNNCGRKIAVSNKELRTKVIDNTTVTYFMCRRCFEK
                     FIVSCEDDYIKHKKEEYKKLKDDEVKLLQDMKEYSDGLGELYINEL"
     gene            complement(19596..20144)
                     /locus_tag="KOU88_002855"
     CDS             complement(19596..20144)
                     /locus_tag="KOU88_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006439283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK3212722.1"
                     /translation="MNFVEPIRDLEKLESMCAYLEEANMRNNVLFSMGIYTGLRVGDI
                     LKLRIKDVHDKRFITIKESKTGKTKPIEVNPILKRILKEYTKDKNQNEFLIKSREQTN
                     KAISRVMAYKIIREVGEMFGIDNLGTHTMRKTFGYHYYKRTHDVVTLQKLFNHSSATI
                     TLRYIGIEQDDLNKAYRNIKYF"
     gene            complement(20321..20782)
                     /locus_tag="KOU88_002856"
     CDS             complement(20321..20782)
                     /locus_tag="KOU88_002856"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212723.1"
                     /translation="MKIKKEYIEKVENILKMLGDKYRKLRILKKEIAILKHKENYREI
                     NFEELGFKVKRSTKGIDDIVVTIEDTIYNKETEIEIIERKLEFYNIYLKELSELEQKM
                     IELIYFYNWDEKLPITKIAYELNYDRTSLYNKKAIAINKIALMIYGDEALA"
     gene            complement(21063..21233)
                     /locus_tag="KOU88_002857"
     CDS             complement(21063..21233)
                     /locus_tag="KOU88_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212724.1"
                     /translation="MGKVEYIVFYYNCETFEVCKKSFSALTDAKVFKNEIIEEYESVD
                     IIKRTVFEELIL"
     gene            complement(21235..21495)
                     /locus_tag="KOU88_002858"
     CDS             complement(21235..21495)
                     /locus_tag="KOU88_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212725.1"
                     /translation="MNFKMIANIPNWTAKEQFEKVLEEVLELKEAVHLKDNKKIMEEG
                     LDVIQAIFTLFKVLKIDKELSEGLKLHNKKLRKRKWKLEKLK"
     gene            complement(21515..21784)
                     /locus_tag="KOU88_002859"
     CDS             complement(21515..21784)
                     /locus_tag="KOU88_002859"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212726.1"
                     /translation="MENNFWWSFMDLEEAEKVVTKESIKDLENAINEIENEAEEVKIL
                     IIKKNGDEKYINFKHDGYMKDVIKDRIVQCFEEIKIIHETILEEI"
     gene            complement(21774..22034)
                     /locus_tag="KOU88_002860"
     CDS             complement(21774..22034)
                     /locus_tag="KOU88_002860"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212727.1"
                     /translation="MKEYRIEIGEMIFLKHKVIVEVPEQICAFDIYKYIENECQDKSE
                     ISEYIEKIGGKQLNFIEGDSGDSDLTVENCKRIKKGEKKNGK"
     gene            complement(22031..22180)
                     /locus_tag="KOU88_002861"
     CDS             complement(22031..22180)
                     /locus_tag="KOU88_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212728.1"
                     /translation="MSNTNKKTAKICGWCGTTVYSYMDGKIAYCSKKCKKKREKNLET
                     EGAKK"
     gene            complement(22197..22605)
                     /gene="ssb"
                     /locus_tag="KOU88_002862"
                     /pseudo
     CDS             complement(22197..22605)
                     /gene="ssb"
                     /locus_tag="KOU88_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420524.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            complement(22620..22793)
                     /locus_tag="KOU88_002863"
     CDS             complement(22620..22793)
                     /locus_tag="KOU88_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3797 domain-containing protein"
                     /protein_id="HBK3212729.1"
                     /translation="MKMINVFKLSSMYCICPKCGSDKLGKNEGKLIVDEHTYYRECKC
                     GFNVLVDEREDEI"
     gene            complement(22852..23067)
                     /locus_tag="KOU88_002864"
     CDS             complement(22852..23067)
                     /locus_tag="KOU88_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212730.1"
                     /translation="MNKISVTQALEKFDSLLDNWNDLPNHVYKKEYRGKFYDWIKSLE
                     RKDSLQNYKIVEVLNNERNGEEAPFWN"
     gene            complement(23060..23236)
                     /locus_tag="KOU88_002865"
     CDS             complement(23060..23236)
                     /locus_tag="KOU88_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212731.1"
                     /translation="MDKFVTCARCERTINVEENNYVKYEEETLNLSFTLYFCLGCVDK
                     LIEEQLKSMEGENE"
     gene            complement(23256..23621)
                     /locus_tag="KOU88_002866"
     CDS             complement(23256..23621)
                     /locus_tag="KOU88_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212732.1"
                     /translation="MNIGSYTLVKKQLVKELEEENKQKEECLKEREKHIKELEESLEY
                     FARDALESEECIIDIENILIEQAVELEAYNLFIDCILNKDIRKAIAIYNRTKSIRIKH
                     KNINSISKKIEKIKQIISL"
     gene            complement(23608..23784)
                     /locus_tag="KOU88_002867"
     CDS             complement(23608..23784)
                     /locus_tag="KOU88_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212733.1"
                     /translation="MQKRITEMSILEKVDLIGQKQKKLQEKYKNLSKGELFSIACNEV
                     KKIEEQEGKYFEYR"
     gene            23873..24217
                     /locus_tag="KOU88_002868"
     CDS             23873..24217
                     /locus_tag="KOU88_002868"
                     /inference="COORDINATES: protein motif:HMM:NF022172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2513 domain-containing protein"
                     /protein_id="HBK3212734.1"
                     /translation="MVTNQDCIRDILLLIESNTTPISPVLQFDTILDNLTYDKSTIVH
                     HINLIYQNNLVDDVNYGDDTVLEVMQLSLKGYQYLDKIRDNTKWNKIKSSTSSFLNMS
                     LPIAIEYILGKF"
     gene            complement(24256..24537)
                     /locus_tag="KOU88_002869"
     CDS             complement(24256..24537)
                     /locus_tag="KOU88_002869"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212735.1"
                     /translation="MIKNNVLSYEEKIKVLKKHGYSDFTKEYVLKEFDKEHAFYKSFL
                     RAIEKEDDGKGVLIKKIGKGQHQFSKGFIKTHTISELLEEAKRIRKILE"
     gene            complement(24583..25185)
                     /locus_tag="KOU88_002870"
     CDS             complement(24583..25185)
                     /locus_tag="KOU88_002870"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212736.1"
                     /translation="MEINSVRELRELFELFTVIKAEGNNVVSCNETVNELSNKELIKA
                     NENKFKKLWNDALLYEINALDIIKKHKHSDRKEKAYKTYLGLENADIEEIYKIHYGDK
                     ENSETVASCEEISSAKTDTISCNHDSVSKGKDTSDSECTCFICSKKIENQEDVFKIPF
                     LTRDYLSSAKEIKNIEICEKCLDSNSWSIIRRKQFKKMKK"
     gene            complement(25210..25302)
                     /locus_tag="KOU88_002871"
                     /pseudo
     CDS             complement(25210..25302)
                     /locus_tag="KOU88_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420554.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
     gene            complement(25648..26082)
                     /locus_tag="KOU88_002872"
                     /pseudo
     CDS             complement(25648..26082)
                     /locus_tag="KOU88_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899661.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(26116..26331)
                     /locus_tag="KOU88_002873"
     CDS             complement(26116..26331)
                     /locus_tag="KOU88_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212737.1"
                     /translation="MKLLKSKNIKIGEIIRLHDVKFNHDRKCIVTYIDKDEIVLTYYD
                     EEIKEMTCKVLTKEDLIFNDYELKLLS"
     gene            complement(26368..26532)
                     /locus_tag="KOU88_002874"
                     /pseudo
     CDS             complement(26368..26532)
                     /locus_tag="KOU88_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904215.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            26761..27105
                     /locus_tag="KOU88_002875"
     CDS             26761..27105
                     /locus_tag="KOU88_002875"
                     /inference="COORDINATES: protein motif:HMM:NF024835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212738.1"
                     /translation="MNIEERLKQLILSKYKSIRAFTKEVNIPYSTVDTMLKRGISGTS
                     ITTVLKICNALNIDADALIDNELKEKELSSKIQTNQFEQKILKMYNALDEHGKDIVFT
                     ILEKEYVRINKL"
     gene            27288..27587
                     /locus_tag="KOU88_002876"
     CDS             27288..27587
                     /locus_tag="KOU88_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212739.1"
                     /translation="MESLLKYHRKKKKLTQRRLSELTGISQSYISRMENKKFKHSPTL
                     TQIILLADILEIDQLILSEFFLEKEREHLKNTKKYNKKAVKTLSRDFLKEYKNKD"
     gene            complement(27615..28289)
                     /locus_tag="KOU88_002877"
     CDS             complement(27615..28289)
                     /locus_tag="KOU88_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212740.1"
                     /translation="MMLKYITKHKNMEESRMKKVLLLITVCLLSVGLVACSSTNNKDT
                     GNTTKKEKKANENEVDGIKITVKDVTKEDIKGDINEDGSFNENGEYFSDGIEKKKAAD
                     YVYEVVNVEVENKTDKAVKLFQTGWNAVGTDGYEFKDIKVTDKLDNQQVPANYKFDAQ
                     VKILVEKNMNVKEIVLKYNLKDYSRLFEAMEYANQGASKSDVEKKFPELYKDNWIELG
                     EIKVEQ"
     gene            complement(28905..29597)
                     /locus_tag="KOU88_002878"
     CDS             complement(28905..29597)
                     /locus_tag="KOU88_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016034219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212741.1"
                     /translation="MSLEEAKELEKNYKLPMPTYCLNEKNYCAKEFGALMLISKGSMR
                     IMHIEKNRYLYQNKFKMEELAKQIGVARTTLERNIKKLNSLDCKVLEIENSRNGIIYR
                     LNYGTSTGYNDNVHKFVTIHHDMLQELISAFNTNAIKVYCLLCYMTTENSFKCMTEKF
                     ICEKIGLCGDSKNNRSKIRKIITVFEVSKYIEVKKENKFEWDEEKNKKVPRIQKLYRL
                     CSFSEWKNARKK"
     gene            30978..31160
                     /locus_tag="KOU88_002879"
     CDS             30978..31160
                     /locus_tag="KOU88_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBK3212742.1"
                     /translation="MEKEKRDLKFNFHKGGSGSFTPRMSVPKKWADEMGITRENPNVT
                     ATFEGDRIIIEKAKNE"
     gene            31471..32280
                     /locus_tag="KOU88_002880"
     CDS             31471..32280
                     /locus_tag="KOU88_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK3212743.1"
                     /translation="MANTKLLTYFNIKGGIYKTTTSIMTAYELAKDKDKKILLWDLDV
                     QANLTQYVYEINHNDNTTLDILKGISANDAIVKSPNEKYINVDLIPSDIQMARFEQEL
                     SPLPAREKFLARWYMQNFNTLSEYDYIICDLSPRYDLTAKNVLFLADSIIIPIQDKNI
                     SSLRGAELFKQLWDVDRTYFDKEDNIKSTVLVGFEKKKTQISDTFDSYLEGFNDMRDI
                     MLDTYIRKNEFIEKALLKKLSLTDYTKITKEHFSRQEFANMLEELKVKGVL"
     gene            32281..32616
                     /locus_tag="KOU88_002881"
     CDS             32281..32616
                     /locus_tag="KOU88_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016040102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212744.1"
                     /translation="MPKFDEELLSNKEKPVFKKNGTIIQNNSTTTDNKTLNIYNLVNK
                     KSKKVTMSATLDEELVNKLKSFSIDMNSDVSKLLSDVLTQILSDVTIKEENLNIYNER
                     NRRNKTKKK"
     gene            32759..33040
                     /locus_tag="KOU88_002882"
     CDS             32759..33040
                     /locus_tag="KOU88_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212745.1"
                     /translation="MNVYLQIGKELSEKMTKSELNKFSQEVANYLQYAGLDKNMKIKL
                     FQTILEMVARKKITLSSDSEFTEGILQSDEAEMTMNVGFIIEGLSYHNN"
     gene            complement(33343..33814)
                     /locus_tag="KOU88_002883"
                     /pseudo
     CDS             complement(33343..33814)
                     /locus_tag="KOU88_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894340.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(33846..34349)
                     /locus_tag="KOU88_002884"
     CDS             complement(33846..34349)
                     /locus_tag="KOU88_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212746.1"
                     /translation="MNIDFSTILDLKVNKENVKMIEKEINKINNDIFDISLKDCANGH
                     IGSVKETVGKSLNIETWGHGEINSKIGIRLRFNFYYSKGDKVDIENIENILIYVNSLC
                     SKNVESDLIANVRPKFYKLEEKYSTRIEKCEIRHEFIGINKQEIKEFLEYLTEIEKSE
                     RTVIYKK"
     gene            complement(34426..35259)
                     /locus_tag="KOU88_002885"
     CDS             complement(34426..35259)
                     /locus_tag="KOU88_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212747.1"
                     /translation="MKILFKEAHKMAREIKRKYSNVDYKVQFSLCLSFLNKKGDIKLK
                     ELKGSEKQIIWANDIRTDILNLTNELEKSKIERIKNEDYKIKDMSIEEMTERCKRKFE
                     RIREAISNIENAKFFIDNFRNVLKYNSLNQKAFHINQILKDSQFAKENRNWSFLQGET
                     QASYRLKKVKDYSISYEEAKKIAKEINFNDNWSNEIKENVLEIVEIFDDAVKQATSTE
                     YIEKAKKYIIETLIQKNAQFYRNGFADIKKKQIENYRKIESDERKIEIAYQVFRDGVE
                     C"
     gene            35438..35650
                     /locus_tag="KOU88_002886"
     CDS             35438..35650
                     /locus_tag="KOU88_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212748.1"
                     /translation="MTWKNEIKSILVKENISMNELNNLMNEHNNKNNTVENLRQKINN
                     ETMKYSEILTIANLIGYEVVWKKKEK"
     gene            complement(35696..36535)
                     /locus_tag="KOU88_002887"
     CDS             complement(35696..36535)
                     /locus_tag="KOU88_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3212749.1"
                     /translation="MKICITVGHSILKSGACTSANGVVNEYQYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKSEEKSYKIPKVNSGGYDLLIELHLNSSGVGAFGTEVFYYSE
                     KGKEYAQRVVDKLSKPFIRKKGDKEVGNRGVKLDKSLYILNSSKPTAILIESFFCDNK
                     EDYEKAKKLGHEGIAKLIVEGVLNKNINNEGVKQMYKHTIIYDGEVDKIPATVVGWGY
                     NDGKILICDIKDYVPGQTQNLYVVGGGACEKISSMTKENYTMIKGNDRFETLYKALDF
                     IDR"
     gene            complement(36535..36966)
                     /locus_tag="KOU88_002888"
     CDS             complement(36535..36966)
                     /locus_tag="KOU88_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK3212750.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPRKLKDRIGSLLDTMTDELNVKGGSK"
BASE COUNT        11099 a         6612 c         4083 g        15207 t
ORIGIN      
        1 ttttcatttt ctgcaattag taattgattt tctaactctt gtattctctt ttcttcatct
       61 gaaataaatg ttggtatttc ctctaaaatt ggttcttttg tttctatatt tatacctata
      121 attctatttc ttgtatagtc tatacttcca tactcaacat caatataatg taattctgtt
      181 attgtatcat gttctagtat atctcctgtt gcttcccctg tctgtagcag tattttgcct
      241 gtctggtcgt aaattattct atttgctcta tccattttat cacctcattt attaaataaa
      301 ttttatagct tgccatttaa aagaagaacc ttgtcttgaa caaggaagtt gtatacctct
      361 attatccata taaacatcac gttcatttaa tttaagaacc tcacctccaa ctttaaaatc
      421 ttgtaaatat gatgttagac gataataatg agcagtaatt acaaaatctt gagtgaaaat
      481 accacgacaa gcaaaaacaa aatatttatg aaaataacca tcatcaatta attcaaaagt
      541 agtaaaaaat atattaggaa caaaattaag tccgttaatt tgaatggctc caggaaatag
      601 gaacagatag tcactattaa aataaaatcc ttttgtatta gtacaataat taacaacact
      661 attgccacta gcaactttat atttagaatt taactgactt atagtgttat tagcttgtgt
      721 taactggttc atcaaatcct gtacactagc gtctgaacta tcaaaacttg tttttatttt
      781 ctctgacaac tcgactaatg tgttatttaa acttgcttct atattcttta gtgccaaagt
      841 atttataata cttgttttgc cacttttgaa tgtatcttta atttctatcc atttacttgt
      901 aacttcatct gttgtagaac cagcaggaag aggtgcaatt cctttgctta tacttacaac
      961 tttttctgct gtagcattag cactgtctgt aacaactatt ttaagtgtgt gtagtgcatt
     1021 atcttctaat gtatagttaa ttattttctc tgttgttaaa tctgttgtta tagtttcttt
     1081 tagtacatca tctataaaat attctatttt tgtaagcaat gtagggtctg tgtggtcagc
     1141 tttaaatgta gcttgtgtgg aattataaga ggatatagtt aaaaaaggta atgcttggag
     1201 taatgttatt ttagcataac catcttgttt cgtagtattt ccacctacaa cgctatttat
     1261 atcgctaaaa taatatttag aagatggact ataatttgct ggcttataac tatcttttgt
     1321 tagaatatat ccacttccac caccaccaaa ttcagcataa aaactacctg caccacaata
     1381 ccaaccacca ccgccaccaa caccactaat gccatctcca gcaccgctta caccaaaaga
     1441 accattataa agactattaa aagttaaacc gccttgaaat tggcttccac cgcctgcaaa
     1501 atatttattt gctatagaaa taccatcttt accttttgta ccaccaccat gaccaatact
     1561 atcatgtgaa tttccgcttc caccaccacc gccacctgca acaattatgc gagatagcaa
     1621 actttgtaaa ttatcccagt taccaccaat aagtctaata tcagtagctc caccacctgc
     1681 aagactataa taaccatcag aagtactttt ataagtggtt ataccacccg caccattaaa
     1741 accacttcta caagtctcaa taccattaac acctttacaa taaccacttt gcccaacgta
     1801 aacatgtaat gtagtatttt ctttcaatat taaagaacca gcagtatagc caccttttgc
     1861 gcactgtaca aaatcataat aattaccacc acaagcacca aaacattcaa acttatattt
     1921 accaggtggc aacactacac tttgttcagc acctgtataa ttaaattcat aaactatagc
     1981 catttttcac tctcctctct taaataggta acatgtcgtt ttgtatggat atattaatct
     2041 cgttaaaatt ttctattttt gcaacaattt catctattgc cccttgaaca tttgtagcag
     2101 taagattact tgttgcatta ttataacttg ttttctctgc tgttgtttct atttttgcta
     2161 actcttcttt tactttgttt atttcattta ataagtttcc agctgcatcc tcatccaaaa
     2221 tatcttttat actttcaaac caaatgttaa actctgatac aaaatttgtt gttgtagtgt
     2281 tataccaatc ttcttgttta ttctcttgat tttcccgcca aacattgaaa ttacttattt
     2341 cttcatcttt ccaagtattt agttgtgcaa gtaatgttgt tgtgtctatt tcttctatcg
     2401 tgccttttac aattccacac aaatttttat ctaatcttaa atctgttata gaactttgtg
     2461 taatacttat tgctccagct ctgatataaa tatcagctaa tccaagttcg tacgcatctg
     2521 catcacgttg taattctgtt gcaactgggg aactattaaa agtacatttt ttaacagcta
     2581 atttaatatt tctatttaaa gtatcaaatc ttaaaactac tctgtctatt ctatttaaaa
     2641 ttccatctgc ggggtctata ttaattacta aatcgtctgt gtttatatag atagctccgt
     2701 taatccagcc cttgcctttt tttactgtta tagtcatatt attattatct acaacttgca
     2761 aattgctact tggattaggg aatacaccat tacctataaa actagcaaaa tattctctaa
     2821 agtcctctgc cttgtatctc ctatcgccat ttacactatt aaatacaaaa cttttttcca
     2881 ttatttcacc atccttttta tttttgaaaa taaggttggt atgctgctcc caaacgtaat
     2941 ttttaatttc atcccatttt tactatagct ttcttgtact tctacaattc tagtatccat
     3001 tgttactttc aattttctat cttgaactgt aacaatatcc cctagtttgt agtctttttc
     3061 atacataaaa gtatttttag ggtctatttc taattcaaaa ctttttaact cttcatattc
     3121 ttttaattta atttctcctt ctttttgtag tatgcttata gtattttcac ttacatctgc
     3181 aaagacttcg tttctctcaa aaccttcaac ctcaccagtt gaaattacca gttttgtcgc
     3241 gtcttctctt gctccagcat acacaacatt tttagagtta attatacttt ctgtaaagtg
     3301 tctagctctt atgttattaa aatcacttct aaaaataacc ggcgggtttt ctgtttgatt
     3361 aatagtcaaa tctttaccag taattacgtc aaaaataaat ttctttttat tagcatccaa
     3421 cactacctcc caaccaagcc cacaaaattc tgatatttct tgaattttat cacttaaatt
     3481 ttcgtaagaa cttcgccaca tatcagcact tccaagattt ttgttttctg aaatgataag
     3541 attatcaatt acacgttttg gatttgaagg gtctacgcag ttattattaa caaaagcttt
     3601 tataatttct tcttgtgtcc cttcgtgact ttcgaaagct tctccagtgt cgggtatgat
     3661 gagccttcta tttaacaagc cttttaaatc cacgccttta acagataaaa tgtcgctttt
     3721 ttctcctgtt tcggtgtaca tgaactctcg atgaagtatc aaacaaactt tattataatt
     3781 tttaccaagt agaattatat tatttttaac taatttatct acatgatttt tattagcatt
     3841 tatttttaaa ctaaactctc ctactttgtg gaatttttta ataatctgta attcttcgta
     3901 attatctatt tcagctatta aatttatatt tttatctagt attcttatgc tctgctgcat
     3961 attacacccc caaataaagt ggattataat atatagacat ttctaaatta tcaattccta
     4021 cgtctgcgtc atatctaaat aaattgtctc caacttcaag ttgtaaaaat tcgctatcca
     4081 agtcaatcca attaaataca tttattcttt catagtttga ttttactaac tctattcttt
     4141 tatttgcaaa ttctgttgtt atttctaata agtcaccagc ttcaagggtt ctgtttatct
     4201 taatatattc tcttgtgttt acattaaata ggctaggatt atcaactgtt gcaagtgctt
     4261 taaattgtat tttcatgcca cattcaacgt ctccgttatt cactacatta caaattaaat
     4321 tacttaccct atgacccatt tctattcctt cattacttat ttctaaagta aattcgaagt
     4381 caccaaccca taaggcgact tcttctttta aaacaaactc atccatccaa aatgggcttg
     4441 gagttaagag ctgtataaga aacttttgca tcaatctaac tggtgtttga aatgttatgt
     4501 cttgcacaac tcctttgaca cgtttagtta atgcgttatt tgtatatata aattccattt
     4561 ctcctaattt aggattaaac aaagaggtta aatatgcacg ttttaattct aaatcttctt
     4621 tattttttgc ataaatagct gctgaaatag gaagtaatct ctcttttatg cttatatcat
     4681 ctatacttac accatcacct agattgttcg agactgaaat attagcacta gtatttgctc
     4741 cgttttctat tttttctaac aaaaaagggc gtgagtttcc taatttaact tcttgccctt
     4801 tcgagtttct acatattaat ttttgcaagt ttcacacccc tttttttata aactattttt
     4861 ttataaacta aatgctagac ttcttattgt tctttcgatt tctcttgctg tgtttgagtc
     4921 tgtactatta acgtttacat tataattcgc tgttcttgaa ttattattat aagttgcttc
     4981 tcttcttccc gaatttgaat tagctgctga atttcctttt ctaatatcgc tatttaaact
     5041 caatgcttca tttctagcat tatttatttc tcttgtaata ctatcaatta gatttttaat
     5101 ttcgtttatg gcaggcttaa atccttcaag taatttttca cctagagttt gacctgcatt
     5161 tttatatgca tctgaataac tatttaataa cgcaactatt tctttttgat ttttatccat
     5221 tatcaatttt tcagcttctg cttgaagttt tgattctttt attctttcat catagaactt
     5281 tttagcgtct tcaagtcttt tattataata ttccttttcg ctttcataga tttgatttat
     5341 attttctatt tcgtcttttt tcttttcttc taattcttct tttctctttt ttaaagcttc
     5401 ttttttatct tctatttctt gttgctctat tctttttttt ctttcagcta aaaccttctc
     5461 tagttctttt tgcaactgtt ctttgttagt atcatcatgt tcaaacttta tagctgtttt
     5521 aatttcttct attttgttta attcttcttt gtcttgttca agtctatctt tttccttttc
     5581 agctttttca aaagcttcta attcgttgtc aatagcttta attttcgcat catagacact
     5641 attaattcta tctatacttt cttccttcca tttatctagt gcgtctaact ctttttttat
     5701 actcgcttgc tgtgcttcgt attcttgttt gtatttttct ttcagcgcat caactattgc
     5761 ttttgttaag tcatcaactt tttttacaaa ctcttgtctg tcttgtaact ctttattcaa
     5821 ctgttcttta gctgaatttg ctatctcttt tagctgttca acttcttttt ctttttgttc
     5881 ttttcttagt gctatcgctt cttttatttt ttctttttta gctgcatatt cttctttcaa
     5941 tgcgtcttta gcgtcacctt ttactttttt aagcgctgct ttttcttgtt tagataattc
     6001 gtctatttgt ttattaaata gttttatatc ttcttcgcat gcttttgtag ctttctttgt
     6061 ttcttcttct ataatctttg ttatcttttc agttgctttt ttgaccgagt cgctattatt
     6121 agcaatccct tgtgctaaac cttcatcaac gaatttacca atctcagcca taacacgaga
     6181 tggagaatgt attcctaaca cttttctaac cgcatcagca gccttttgcc ctagtttttt
     6241 ggcttcgtct actactttat aagcaaagcc ggatatacca ttcgctaagc cgcttacaaa
     6301 atctttacca acttgcagga acttgcttgg gaactctttt attttgttta caacatcagt
     6361 cccgactttt tgagatgcat taacagcatc ttgttttttt gagtctatac cttctcttag
     6421 tcttgtaaac atgtcgatag ctgcttgttt taacttggct ggaagtgttt taaaaaatgt
     6481 aattacatta ttccaagttg tcacaatatt atttttaatt tctcctagtt tggttgttac
     6541 agctgttttc atactttccc acgcgtttgc aagagttgac tttatatttt cccaagtatt
     6601 ggagcaaatt gtttttagcc cttcccaagc ggtcgaacat gtcgacttta tattctccca
     6661 tataccgctt agagtttgtg ttatagactc ccaaatagtt attgcagtac ttttcatact
     6721 ttcccacatg ctagaaagta aatcacctat tgcagctaat gcattgttaa atacttctct
     6781 tatagattcc catgtatttg aaagtccttg ctttatattt tcccaaattt gcaaagcgtc
     6841 tgtttttaac ttatcaaaat ttcctgttac aacatctaaa attaataaca cagcaccaag
     6901 tactatattt tttataactt cccaagtact tctaaaaaac tcttttatac catcaaatat
     6961 aatttttaac ctttcgatga aaggtgcgaa tttttcttca acttgttgtt ttatagcatc
     7021 ccaagcgttc ccgaaaatca tttttatatt ttcccacgtt gttgtaaaga ataattttat
     7081 agactcccat ttttcgctaa tactttgttt tatttcttct atctttaagc ctatagactc
     7141 ttttatctct gtccatttag ttgtaacaga aagctttata ctatcccaca aaagtgctgt
     7201 attttctttt aaattagtcc atccagtcga aattttttcc tttaaacttt cgacccagct
     7261 accagctata tcgtcccact cttgcatttt tccttttact gtatcgttta aaacttgcca
     7321 ttttgacttg atttctcctg ttgtccagtc aactttattc gcttgatttt ctgcttgttt
     7381 ctgtgcttct gcaacgactc cttgatgcat ttctttagct ttatttattg attcgtcttt
     7441 ttgtcttgtt gcttcttcta ctactttgtc cgctaacttt tcattttcta cgccaccttc
     7501 tgctctaagt tgtgcagcta tttttaatct ttcgttatat tcttcattag ctgcttttat
     7561 actttcgtct tttttcttta ttgagttttt aactacttcc gcagcctctt tagctgacaa
     7621 atcaacatga tttgctttca ttctttccat tattgcagct tgctctgctt cgcttttact
     7681 cattgtgtca actgcggtat ttagcatatc tgtttttatt tgatttatct ctgctgattc
     7741 ttcttttgtt aatgctctat gttcttggct agctttagtc attatttgat ttactttttc
     7801 attgctcttt tttatttttt cttctttgct tgaatatgct tcttctgtat tttttattaa
     7861 ctcttctttt tctttgtcac ttaaattttt agaagttgca aacatttctt gcaaagactg
     7921 aataccttgc tctttactct cttgaagttt agcaacgatt tgatttgaca tttctgtaaa
     7981 attagatact attgtctgtt tcattttctc tgaaacagtc tcaccactcc acattaattg
     8041 atttaaagat actgttgtct tttcttctaa atccataaaa gcgcctacag cttcttttgt
     8101 agattctgat atgtttttac caaaacggtt aattggctct atagcatctt ttgacatatc
     8161 tttagcgact gttgcaaccg atatgcctag cgcagtaatt ccagctacag ctatagccgc
     8221 agggcttgat aatgcaccta aaatcgcagc taaagcacca actgctggag ttgctgcggc
     8281 tgctccggtt gttgcgactg ccattgccgc tgaaaaagta ccaaaagccc ctataactcc
     8341 acctatcatg ctaactattt ttccaccaat aagtaaaacg ggtccgagtg ctgctgctaa
     8401 tcctgctatt ttaactatag tttctactgt agcaggtttc atttcgttta atttatttgt
     8461 aaggttttga aaccagctaa ctacttgcgc tatagaaggt tttagtacat catatatttt
     8521 aagtcctaat tcctgtacag ctgatattaa agccgttata gaacctttat tattattttg
     8581 catagtctta gccattttat ctaatgcacc tgtgctattt ccaacctttt tttcaagttc
     8641 tgaatattct tctccaactc cagatagcaa agcttgcaaa gtagatattt gcgtttttcc
     8701 acctatcatt gacaaataca ttgttcgttg ttcttctgtc atgtcttttg ttttttcttt
     8761 aagttccatc aaaacattag ccatgccttt gaacttacta ttagagtcaa aagcacttaa
     8821 tcctaattct ttcatagcta caccagcttg acctgctcca cttgtcagat ttatcatgat
     8881 agagtttaaa gaatttcctg cctcgctgcc ttttagtcct ctatttgcga gtattccaag
     8941 tagtgcgtta gcttccgaaa gaggtacgtt taaattttta aaagtacctc cagacacaat
     9001 catagcttcc ataagtgcgt caatgttagt gtttgaactt gcagcagttt tggcaacttg
     9061 gtctaaatat gttggcaatt cttttacact aagcccgaga cttgacatag agtcagttac
     9121 taaatccgag gttcttgcaa ggtctaaatt tccagcttcc gacaatctca aaacaggcat
     9181 caaagcttcc attgatgttt tcgcatccca gccggccaaa gccatatacc caagcgcatc
     9241 agccgcgtct ttagctgttt tggatgtaga tgctcctgct tctctagctg ctttttcaag
     9301 ctgaaccatt tcgtcagctg ttgccccact taatccttgt acatttgaca tagatgcttc
     9361 aaaatccatt ccaagcttac tagccgctgc tccgactgct aaaacaggag cagtaatact
     9421 catagccatt tttttaccta cgtcttgcat ttgttttcca accgagctaa atttgttacc
     9481 tatttcagtc attttagttg ccagctgatt ccatttattt tcttgctgat ttattctttc
     9541 tgttgtgtca tctagttctg aacgcatttc agaaagtctc gactctgcat tattaactcg
     9601 aatagaccaa ttatcaaccg ctgccgagtt agaccttatt ttttcttcat ttttagcata
     9661 ttcttgctct aaactatcaa gttcagattt taaccttttt gtttcttctg cattttcacc
     9721 taatgtcgtt ttgctctgtt cgtaagcact cttagcttga ttaacttttt ctttaagttc
     9781 aacttgcttt tgtgctgtgt tgcttaaagt tgttttactt tcatttagtt tatttttata
     9841 tgcttcaact actttagttt gctgctgtat agtactagat aacatttgtt gcttagattt
     9901 caaaccatca agacttgttc caaaattttt cactccagca ccagaatttt taaactcact
     9961 tcttattaac ttcatttgtc tatttagatt attaacccct tgctggaatg aactattttc
    10021 catcgcgacc cgaacaacta attcgcctac atcttccgcc attttctcac ctcacttgca
    10081 aaaaaataaa ccaagataaa atatcttggt ttattttata taaaacttat tttaaattaa
    10141 ttttcttcca caaaaagggc aaaagttaat aggttcaaaa ctttcactat agtaaccaca
    10201 ccaacattca gaatttaaaa aatactcatt gctttctttt tcaatccaca tttctatatc
    10261 gcagtcacaa gttatcaact cgcctctatt tgttttacct cttttaaaag ctgcttcgct
    10321 ttcttcaact tcacagtact tacacataca ctcacatcct tataaccagc ttatctggtc
    10381 aatataaacg tcattttcgt ttggattatt attatctttt ttattctctt tcgtatacgc
    10441 aagtatatct aaataataaa atatatccat gttatctata tcaaccatac tccaattctt
    10501 ttcaaataaa aacatactat ataaatcttt tataaagtca cgtggagata gatacctatt
    10561 ttctttatta gaattatttt ctgtatcttc tccattacct agttttttac tttttcctca
    10621 aaacctccac ttacttttga taaatcttct aacgctttat ttataaaatc accagctgga
    10681 taaaaaccat ctagcaactc atcttttgaa aattgttccc cgtatatatc aactgtaaaa
    10741 tcaagcaatt cgcggaataa ttctgtagag ttaagaccat cttcgatttt atcggttagt
    10801 gtaaaaactt tatctaattt tctaagtggt ataggtggag ctttgaatat tttttcttct
    10861 tcatttatag ttaattttat ttccattttt tatttcctcc ttatttattt aaatttgctt
    10921 tcgctggtgt tgttggtttt actcctgttt ttaaaaaatc tgttgtaaaa aattgtgcat
    10981 cagtaggtgc attttcgacg tccgtatctg cggttatttt atgtctacca tcatgtatcc
    11041 ttggcataaa tttaagttta attttttggg attgaaattc gattttatcc tcttttgttt
    11101 ttgcttcttc ttcgaaaggt tcacagacac ctttagttaa ccaaaccatt ctgcttccgt
    11161 tttggctctt cggggattca aaaccaaaag caaggtttgg aggattgaaa tttttatcct
    11221 ctatcaatac accatcttta tattggtatc caaggataag cgcacgttct tctaatgtta
    11281 agtcagcgac ctcaatttcc acctctatag ctcccatagc cgaagcagtc tctaaaagct
    11341 ggtcgtcccc ataattttca gcagaatcaa ccttaggtga tatttttaca cttttagcac
    11401 ctgttaatct tgttatttta gtatcgtatt caagtgtttc ctctgtatct gttagtagct
    11461 ttacaattct atagtttctt aatcctataa tagccatttc ttaatcctcc tttttttctg
    11521 caaaaataag aatctaaaaa cagcatggta actataatca gattctttta tttcgtgtat
    11581 acttcttttt ataaaattat tttttttaag cagtctttca atttctttat ttatataact
    11641 cattttattc ttactaaaca aatctatttg tatataatgt tctgtgccta tcacttcatc
    11701 atttgcataa aaattttgtt ctaaataact aaagaaagtt atatatgttt tttcttctcc
    11761 attatacctt tgaaatgaaa caggtatttt taaaggtttt aatgtttcta ttactaaatc
    11821 atttatatta atcattataa ccccaaccct ctttttaata tttctttcat tacattttta
    11881 gcttcatctt tttttgattc gtatgcgggt gctagaaacg gtttagaact ggttcctgga
    11941 tgatttacta cccttccttt tttcttacct tttttaattg gtattttatg cgcagatgct
    12001 ccaaactcta aaaactttcc ataaaaaatt tctgaattat cctctttcgt aataccaact
    12061 aaaacatact tagtaccacc ttttttctta actccactta cttttaaacc atcttttaac
    12121 tttccgcttc ttttgcttac ccttggtaat gcatcttgca aaataacatt accgccagct
    12181 tttacagctt catttaacag tttatcgcct gttttaccca tgctttctat tttagataaa
    12241 atagcgtcaa atccttctgt tgttatctcc acactcattt aaacaacttc ctcatattta
    12301 aattttaatt ctttacaata atattcattt tctataaaat cactagaatt taaaaagata
    12361 aaattttctt ttttaaatat atcttttata ctaatatatt tgtttatatt ctttaagctc
    12421 ttataccaat attctatttt tattgaatat acaatacttt tattttcatt atcagaaaaa
    12481 tttgcatcat attcattttc tataaaaaat attatatatt cttcatcatt tgaaaaattg
    12541 tcgtattctt gaaaaccaat acctagattt aattttttaa gtatagtaac tatttttgag
    12601 tgcatactat ctcctaactt ttttttactt agattctgct gttatttcaa gtattttatt
    12661 ttcttcttct aaatttaaga tttgagttat attataaaat ttatctttgt atttaataac
    12721 aaaattagtt atagcatttt gttttatact taaatctaat tcttcaatat atctaatttt
    12781 aaacttttta tttgtagaag ttttaatcga attattttct atcaattctt tactatttaa
    12841 atcttcaaca caagcccaaa tttttttata aaattttatt gttacatcct caagaacatt
    12901 ttttctctct ttgataaaaa tagaaatatg tttatctaat acgtcaacta attcagttaa
    12961 gtataaatac acactagttt tgtcattgct aatatcaagt tttactatgc tgtaaaattc
    13021 attatttaac tttataacat cacttgtttt aattaatctc atgtaaggaa cttttaattt
    13081 aatagatacc tttaaccctg tatcgtcaaa tttaagtttg tcttgctctc ttatatattc
    13141 attagaataa aagagtttac cacttacaat aaactctttt tcatctaacg cattaccttc
    13201 tatatcataa ctttccttgt attctccaaa ctcaacaata ccatcattaa aattattaaa
    13261 ttttattttt ttcatatcta tattacctca ttagctgcac ttttaatttg aagtctaaga
    13321 agctctttac taaaattttc ctcgaaatat tcaatagcat tgtttcttac atatctgcaa
    13381 taattaaata gcaattctct attaaaatta tctttaaaat ccagtgctat tcctgctatt
    13441 tcattttcaa agtaatcaat tcctcttaca accatttttt ctatttttgc atcttcttct
    13501 atccaagtta tatttagata ttcttttacc tcttcaacta cacttttaat gttttcattt
    13561 tccatatatt tcacctattt cgctctagca gctgacgttt ttgtgtttga attaatttct
    13621 gttgctaaag ttgtgtctaa gttttctata tcaaatacta aaaatgaatc attgtctttt
    13681 ggcgctcctg ttgcatattg ttttactaga taagttcttt cgtcctctaa aaatttatat
    13741 tcgtctgaat actctatttt tccgcttgaa gcaactccca taaaataatc ttttgccata
    13801 ccagctatta atttaccttt agggacagca actgattgaa ttatattccc agggataggt
    13861 aaaactccat acacataagt accattagat gttaacatag ttgtggcagc gaaaatttta
    13921 gcccagtaat caaccggatt tacaagcatt ataacgcttg ggactgccct tttaccattg
    13981 tttgtaagtg gtgccataat ctctttgcca agtgttattg gtttaaaatc agccagtggt
    14041 tttgcagttt tgtctggaaa tacgccttca acgactgcgc cttttaaatc ttttatcata
    14101 cctttcggct ggtcttttcc tgttcctgct actattccca tttcaagccc caatgatata
    14161 gattcagtca aaactactct tacatatctg tctaaccatt cagcccctaa atcaagcatg
    14221 gcttttgcaa ctggaagata agcagataat ttataagctt ctgtattaat tttatcaaat
    14281 ccatgctcta gctctttttt gatagtatca tctaatctac cccaccatgc agcttctgcg
    14341 ttcgttttcc ttattatcca ctccgtaact cctgttgtat tttcaaaagt tatggcacta
    14401 agcaaagggt gattttgttc taagtcgtca aatactctat caaatacagt acgtggcata
    14461 gttatctcta agttggtaaa tcctcttttt tctataactt tactatagta tactctttcc
    14521 tcgctagtta attgcggcat ccctcttttg tcaagtattg ctctgtcagc tgattctata
    14581 ttagcaatag aacgcgcttc ttttagtaga ttttcttgta tatcttccgc catcctcaaa
    14641 aacgcagttg ttattttttc ctcgtcatta ccctttattg cttccattaa atctgctctt
    14701 agttcaacat tagttgcttc atctaaattt ttaattgcca tttttatttt cctcctcgat
    14761 taaatgcatt aaaaaaagcc gatactaaat cgacatttct tttttctatg ttatctttat
    14821 tatcattttg ctttgtttct tctttttgcg attctctaag ctcctttata gatatatcac
    14881 ttctacaatt tatttctgtg tcattgtaag ctggtatcgg ggttgcagta atttcaaaca
    14941 attcaacttc cgtaatatct ctgtaaaatg tccaatcatc atcccatcga gttttagaat
    15001 ttacaatatt aaaaccaaaa gaacatcctt taatcaatcc aagccttaca ttttcaagta
    15061 agtcattacc atctgttgta gctggtatat ctacttcaaa ccttaaccca tgttcatctt
    15121 cttctaaaat tagatttgag ttagttctac ctacaacttt gttccaatca tgatttatga
    15181 gcataaactt atctctagtg ttatctgcta aagtttttaa aaatgcacct cttgaaattt
    15241 tttcataaaa ggtatcgccc catctatctt gtaacttagt gtaatcgtcg ctaaaaactg
    15301 ctgcataacc acttatctta cggctttcta aattactatc ccttatttcc agcgacaccg
    15361 ttcttttctc catttccatt gttagcccct cctttcaaat ctggatttaa aattgactga
    15421 tagtttttag ttacatagtg ttcatcagcc caagactcgt ttattttttc tctgccaagc
    15481 atttctaaat tgtcatttat agaatttaca cctattctaa ataataggtc gcttgctttc
    15541 gatatttttt caagtcccat attagcaatt ttttgtgtat ctacttttac ataactcttt
    15601 tcaaaaaaat tatctctacc atacattttt ctagttaatt catttgtaat aagttttgct
    15661 actggattga cagaaaaatt caagaaatta tctgttatac cttcaactcc agcaacatta
    15721 ccttttacaa gtccagcagg aacatgaaaa gcagcgcata caaaatccat gacgtcatca
    15781 ataatcgctc ttatatccct gctatctttt atacttgaag cttttgtatt ttctgtatat
    15841 tttaatccat ttgaaagcgg taaaacagca ttatcacttt caaaataacg tttaaactta
    15901 ttactcatca aatcgttaag tcgttcctgc gcttcttttg tctgcgggta atttgtgtct
    15961 atttcaagta cgcccttttc gctattattt tttttataac ccttcatggc actacttaat
    16021 aaatctttat aatcattata aagataatct attacagttt ttatactttc aacatttaat
    16081 ttgaaatata aaacatctga ctctctaaaa cttctatcta atttatagtt tctaattgta
    16141 acatctttgt atatatcttc ataaaaaaca tacttatcta cactaaaact ttcagctacg
    16201 aaaagttgtt cgttttcttg tataactaga cattcattgt catacacaag tcttgtaatt
    16261 acttcttgcc aaaattctgt tgcgttttgg ttttggttag gttctatatt aaacaagtaa
    16321 taattttttt ctttaataga ttttccattt ttaaatgtct gaaattcact taaaactaaa
    16381 gcatttgcaa taatagaaat acatgacttt aacgcaaatt ctttataaaa tatcgtagct
    16441 tctagttttt taaaatattc tccatctgct cctgacattt tatctttaaa taaaaaatta
    16501 cttataaaat ttttaaaatt caattcacca cctcattatt aatacgtata acaatcataa
    16561 aacttaattg ttgattcttg catcagttca tcatcttttg ataaagcatg taaaaacgca
    16621 aaaaagccat cagttttccg cttgattggc tctatcttta aaaaagtttt atttcctttt
    16681 ttgtctgtat ctacataaac attattagta taccaacgca tcatcatgtc gtcgccccac
    16741 ttaattgtcc tctctgcgaa gatttgttct acaagagggg ctatttttgc gtgagttatc
    16801 gacccatttc gaacttcttc aatcggtaaa cctttgttag taaactcttc ttttacatgt
    16861 gcagctctat aagagtcaca acagattttt aatatattat aatcttctgc tttttcaatg
    16921 aaccaatcag caatatattc cgcttttatc gtttcatcat aaattattgt gcagagacct
    16981 ttttgctttg ctaattcaat atcaaattta aaatttgtta tttctaaaga cttataacat
    17041 ataaaagtgt gatgcatgat atatcgtttt ttatcttttt taaataacaa taccacgctt
    17101 gtaaaatctc ttatactaga aaaatctaat cctccaatgc acgaaaagcc ttttaagtct
    17161 ggtaattctt cgtttgttgc aactatgtca tcccattcag cgacaacagt tgccaaatct
    17221 tcagctggca aattaaatct tttagttagt agctctatca tcatttgtgg tctattttta
    17281 gctttgtcaa tgtcttttaa aatttgtgtc cttaagtctg aattatactt tatacttggg
    17341 tttgcctttt ctagcaaatt aacatcttcc atttcttcta tactatcaag tttaaaaata
    17401 agtggcagca ttttagagtt tttaatttct tcatttaaaa tttgtttagc ttcttctttg
    17461 aaatcgtcta atactccacc tcttacattc ccatcagttg taatataaaa aattctagga
    17521 ttttttactt ttccaagcgc agaggtaaag acttttatat tatcataatt ttcgtatgca
    17581 tgaacctcat caaaaataat gcagccgggt cttaatccat cctttgactt agcattattt
    17641 gtgcggaact ttaaatagct gttagttttt ttaaatgtta ttacttcttt agttctgtta
    17701 aaaaactttt tacatatagc aggatgttca gataacatgt tataaacatc atcaaaactt
    17761 gtttttgctt gttcctctga cattgcaaca atgtcaatac cataattttt tacaccatgc
    17821 aagtgcgttt gtaaataatt agctaattgg gatataaaac catttttccc atttccccta
    17881 cccatcatga taaaaatttc atcatataaa agttcgtcgc cttcaaagca gccaaccact
    17941 aaagcaacaa caaatttttc ccaagcatac attttataga aatacttttc catatattct
    18001 atagcttttt caactttttc atggtcgata tagatattag gtttttttaa atcttttttt
    18061 attttcttaa ctgcaagttt catttcttta catagaacaa tttcgccttt atcagccaag
    18121 ctgaaatact catctatgta tttattgtac ttataattca atatcatcat cacccaaaac
    18181 ttttggcgtc gcttttatac ctagtttatc aagtaaactt aacatttgag cgttatactt
    18241 gataagctct gatacactat cgtttttttt atagccccat tgattttgac catttttgta
    18301 tttaacttga acacctctag tttttacatc ttctattaat tcatttttta tatcccacat
    18361 ttttaaatag tcttcaacta agtctttgaa gtattcttct gtcatgttat tctcttttat
    18421 ttgtcttaat aaatcttttc ttatagagtt ttttaaatta tttcccgact cttgcaaccc
    18481 atttttcacg caaccctttt ttggggtgca gttgcgagtc caaccccctc tttttctcca
    18541 acttttcaaa gtgttttcgg gtatgttata cttggctgac atttctttat aagtcatacc
    18601 taaaacgtag tcattctgta cgtctcgcct aatttctaat tcctcattat catccatttt
    18661 caccacctca tttttatgtt ttttctgcac ccgcaaccat gaattttggt tgcaagaccc
    18721 ccacccccca caccttttgt taaattggtg tctccttgcg gagccatgta cctacctcgg
    18781 ttcacaaatt ttcgctctga aagccagttt tttcaatagg ggggctatct accagcgttc
    18841 atcactaaaa aattttttct ttttttcttg attaattttt agtatttttt cgtgaatttc
    18901 gttgtgacaa aggttgcaca agcttgttag gttattaagc ttcaaagctc cttctggata
    18961 ctcttttatt tctctaatat gatgtacaca ttccgcctta gataccttct tttttttctt
    19021 acaaacttgg cattcgtaat tatctctttc aatagctttt tttcttaatt tacgccaatc
    19081 cgtgcttcta tagaatatat caagtctatc aattaaaatt aattctttta atctatctag
    19141 tgttatatgc ttataactca ttgatataca actctcctag accatcacta tactccttca
    19201 tgtcttgcaa tagcttaacc tcatcatctt taagcttctt atattcttct ttcttatgtt
    19261 taatataatc atcctcgcat gatacaataa acttctcaaa gcatctgcga cacatgaagt
    19321 atgtaacagt agtattatca ataactttag tccttaactc tttattactt actgcaatct
    19381 ttcttccgca attattacat ttaaacctat catatttatt catagtgata ctcctttaat
    19441 ttcctagtcg agtttaacat aaggtatatt ctgttaaact cattcaagta ttattaaaca
    19501 gccttacatt ttagtactaa caatacattc aagactttat tattagacta tattttatcc
    19561 agtttaacgt gaccttttta tgttaaattc ttaagctaaa agtatttaat attcctatat
    19621 gctttgttta aatcatcctg ttcaattcca atataacgca aggttatcgt cgctgaacta
    19681 tgattaaaaa gcttctgtaa ggtcacaaca tcatgagtcc ttttatagta atgataacca
    19741 aaagttttac gcattgtatg tgtgcctaga ttatctatgc caaacatttc gcctacttct
    19801 cgtattatct tataagccat tactctactt atagctttat tagtctgttc tctactctta
    19861 attaaaaact cattctgatt cttatctttt gtatattctt ttagtattct ttttagaata
    19921 ggattaactt caataggctt ggttttacct gtcttacttt ctttaatagt tataaaccgt
    19981 ttgtcatgaa catcttttat tctaagcttt aatatgtcac ctactctaag tcctgtatat
    20041 atgcccatac taaagagcac attgtttctc atgttagctt cttctaaata agcacacatg
    20101 ctttctagct tctctaaatc tcgaataggt tctacaaagt tcatttactc acccccttcc
    20161 ttttcggcaa taaaaaaagt ctaaacttcg agccaagttt agactttagg ttcaagggga
    20221 tattcagttg ttaatgtaca cttttttcta tgatacaatt ctaacatgct ttctttagaa
    20281 atgaagtata aaaatagtct tttttttgta aaaatattgt ttacgctaaa gcttcatcac
    20341 cgtatatcat tagagctatt ttattaatag caatagcttt tttgttataa agactagttc
    20401 tatcataatt taattcataa gctatttttg tgataggtag tttttcatcc caattataaa
    20461 aatatattaa ttctatcatc ttctgttcaa gctctgataa ttcttttaag taaatattat
    20521 aaaactctag ctttcgctct ataatttcaa tttcagtttc tttgttgtag atagtatcct
    20581 ctattgttac aactatatca tctatacctt tcgtacttct tttaacttta aatcccagtt
    20641 cttcgaaatt aatttctcta tagttttctt tgtgtttaag aattgctatt tcttttttta
    20701 atattcttaa ctttctatat ttatctccta acatttttaa tatattttcc actttttcaa
    20761 tatactcttt ttttattttc atttttgcac ctcttgcact ttttgttata aatacctaac
    20821 taatccttaa attaaggttt ggggactagt taggcaattt gtagcatttc caactactgc
    20881 atattattca aaatattctg gatttttatt ttgttttttt gttataagac ttcatttttt
    20941 taagtttaaa caaaatctat ttatataaat acttttatga ataatgcttt aataattaat
    21001 gtaaatccaa attatttatc ttttacactt taatttatat ttttgccgtt tttgaatgtt
    21061 aattacaaaa tcaattcttc aaaaactgtt ctttttataa tatcaacact ttcatattct
    21121 tctattattt catttttaaa aactttagca tctgttaaag cactaaaact ttttttacac
    21181 acttcgaatg tttcgcaatt ataataaaaa acaatatatt caacttttcc catgttactt
    21241 taatttctcc agtttccatt ttctttttct taactttttg ttatgtaact tcaatccctc
    21301 tgatagctct ttatcaattt tcaaaacttt aaatagtgta aaaattgctt gaataacatc
    21361 taaaccttcc tccattattt tcttattatc ttttagatga acagcttctt taagttctaa
    21421 aacttcttca agtacttttt caaattgttc ttttgctgtc caatttggta tatttgcaat
    21481 cattttaaaa ttcatctttt attttctcct ttttttatat ttcttctaaa attgtttcat
    21541 gtattatttt tatttcttca aaacattgaa ctattctatc ttttataacg tctttcatat
    21601 atccatcatg tttgaaatta atatattttt catcgccatt tttcttaata attaaaattt
    21661 taacttcttc cgcttcattc tcaatttcat ttatagcatt ttctaagtct tttatacttt
    21721 cttttgtaac aactttttcc gcttcttcta aatccataaa actccaccaa aaattatttt
    21781 ccattctttt tttctccttt ttttattctc ttacaatttt caactgttaa gtcgctatct
    21841 ccgctgtcac cttctataaa atttaattgt ttgccaccaa ttttttctat atactcagat
    21901 atttcacttt tgtcttggca ttcattttct atatatttat atatatcaaa agcgcatatt
    21961 tgttctggaa cttcaacaat aactttatgt tttaaaaata tcatttctcc aatttcaatt
    22021 ctatactctt tcattttttt gccccttctg tttctaaatt tttttctctt tttttcttac
    22081 atttcttaga acaatatgca attttaccat ccatataaga ataaactgtt gttccacacc
    22141 atccgcaaat tttagctgtt tttttatttg tattagacat tgttatccct cccactttaa
    22201 aatggtatat ctgggtcatc tatagcttga aatccttgtt ggtctaaacc tttcggttca
    22261 aacatatatt ctttttcagt atcatctttt tttatagtct aaaaacttaa tcttattagc
    22321 atgaactttt gtataagttc ttttctcccc gtctttttca taactattaa ctcttataga
    22381 cccttcaacc gctactaacc tacctttacc taaattatta gcacatactt ctgctaactt
    22441 ccccatcacc tcaataggta taaaatcagt ttctttagtt ccatcttttt taatataatc
    22501 tctatctact gctattgtaa aagtcgatac aactgttcca gaacccggta tatatttaag
    22561 ttctgggtct tttgttaatc ttccaattaa aataacacta ttcatttcca gcaccttcct
    22621 tatatttcgt cttctctttc atctacaaga acattaaaac cgcatttgca ttccctgtaa
    22681 taagtatgtt catcaacaat taactttcct tcattttttc caagtttatc gctcccgcat
    22741 ttggggcaaa tacaatacat tgatgataat ttaaaaacat ttatcatttt catatttata
    22801 tacatccctt ctatctaaca aaagtttaag tccttttcaa gttatatttc ttcaattcca
    22861 aaacggcgct tcttctccat ttcgttcatt atttaaaact tcaactatct tataattttg
    22921 taaactatct tttctttcaa gtgactttat ccagtcataa aatttacctc tatattcttt
    22981 tttgtaaaca tgattcggaa ggtcgttcca attatctagt aaactatcaa atttttctaa
    23041 tgcttgtgta acactaatct tattcatttt ctccctccat tgattttaat tgttcttcaa
    23101 ttaatttatc tacgcagcct aaacagaaat acaacgtaaa acttaaattt aaagtttctt
    23161 cttcatactt cacataatta ttttcttcta catttattgt tctttcgcat ctagcgcatg
    23221 ttacgaactt atccattatt aaacctctcc tatttctaca aggaaattat ttgttttatt
    23281 ttttcaattt tcttagatat agaattaata tttttatgct taattctgat gcttttagtt
    23341 ctgttataaa tcgcaatagc ttttcttata tctttgttta aaatgcaatc tatgaataaa
    23401 ttataagctt ctaattctac agcttgttct atcaaaatat tttcaatatc tattatgcat
    23461 tcttctgatt ctaacgcatc cctcgcaaaa tattctaagc tctcttctaa ttcttttatg
    23521 tgtttttcac gttcttttaa acattcttct ttttgtttat tttcttcttc taactcttta
    23581 actagttgtt tcttaactaa tgtataacta cctatattca aaatattttc cctcctgctc
    23641 ttctattttt ttaacttcat tacaagcaat agaaaacaat tctcctttac ttagattttt
    23701 atatttttct tgtagtttct tttgtttctg tccaattaaa tcaacttttt ctaatatact
    23761 catttctgta attctctttt gcatttgctt tgctccttct cgttctgtta cagtaaaatt
    23821 tattattgtc tcgtttctcc tgtgctatac taaagcaaaa ggaggtgata ctatggttac
    23881 taaccaagat tgtataagag atattttatt acttattgaa tctaatacaa ctcccatttc
    23941 gcctgtatta caatttgata ctatactaga taatctcaca tacgataagt caactattgt
    24001 tcatcacata aatttaattt atcaaaataa tctcgttgac gatgttaatt acggtgatga
    24061 tactgtttta gaggtcatgc agttgtcttt aaaaggttat caatatttag ataaaatacg
    24121 agataacact aaatggaata aaataaaaag ttccacttca agttttttaa atatgtccct
    24181 acctatcgca atagagtaca tattaggtaa attttaattt aagtataagg tttagattat
    24241 agacatttct aagccttatt ctaatatttt tctaatacgt tttgcttctt ccaataactc
    24301 actgatagtg tgtgttttta taaaaccttt tgaaaattga tgctgacctt ttccaatttt
    24361 tttaattaac acaccttttc catcatcttc tttttctatt gctcttaaaa atgatttgta
    24421 aaatgcatgt tccttgtcaa attcttttaa aacatattct ttggtaaaat cactataacc
    24481 atgttttttt aatactttta ttttttcttc ataacttaaa acattatttt ttatcatttt
    24541 ttcactctcc tttttcacat gtaaagatac taatttaaat atttatttct tcattttctt
    24601 aaactgcttt cttcttataa tactccacga attactatcc aaacatttct cacaaatttc
    24661 aatatttttt atttcttttg ctgaactcaa ataatctcgt gttaaaaaag gtattttaaa
    24721 tacatcttct tgattttcta tttttttaga acaaataaaa caagtacatt ctgaatcact
    24781 agtatcttta ccttttgaaa cactgtcatg attgcaagat attgtatccg tttttgctga
    24841 actaatttct tcgcaacttg caacagtttc agaattttct ttatctccat aatgaatttt
    24901 ataaatttct tctatatctg cattttctaa tcctagataa gttttatatg ccttttcttt
    24961 tctatcactg tgcttatgct tttttattat atctaaagca tttatttcat ataatagagc
    25021 atcattccaa agttttttaa atttgttttc atttgctttt attagttctt tgttacttaa
    25081 ctcgtttaca gtttcattgc aagaaacaac attgttgcct tccgctttta taactgtaaa
    25141 aagttcaaac aattctctta actctcttac gctattaatt tccatttttt taccccacct
    25201 tttttaattt tatttaaatt tagcactttg acttttcttt ataattgcat caagttcatc
    25261 ttctgaatat ttatcaaatg tttgattgaa attagcaaat ttattattat ttgtctttgt
    25321 ttttcctttg acgctctcat tgccttttag agacttttta ggtgtctcgt ttaagtaaga
    25381 ctcgaatttg tttccaaaca acgtctcagg gcgtaaataa gcgttcattt tatcatcatc
    25441 tagccaattt aacactttgt tatctatgac cttgtaaaat tcttcttctg taaagccttc
    25501 tttgagtctt gcatcaatca aagatatagt tttctttgtt gtactcttaa aagatttatc
    25561 tgctgtttta tttaagtaat caacgattct tttatatatc tctttgtctt ttgtcttttc
    25621 ttctttttgc tctgcagaac tatatatatt attagttaaa ttagtcttgt taatattagt
    25681 cttgttactc agcacctcat tcctaacatg tacagcacca catgccgtag ggttaagcac
    25741 ctcattccta acgttaggca ttgtgtgctg cacctcttgt ttagctgata ataatatata
    25801 tagattgctt tctttttcat tactaccttt tcgcttgcgg ttttttctta taagtaaccc
    25861 tttttcttct aaacttttca aaacatttga tacttgcctt tcgctgcatc cggctttttt
    25921 agatattgtc ttatagcttg gaaaacaaca actttcttca tcgctatatc taattaaaac
    25981 tatataaatc atcttttcgt atatgcttaa atcttctcta tcaactaaac tattttctgc
    26041 ccaaaaccaa tctcttttcc ttgaatcttt taaaagttcc aatccctcac cccccttcca
    26101 cttataaatt atttattaag atagtaattt aagttcatag tcattgaata tcaaatcttc
    26161 tttagttaat actttgcatg tcatttcttt tatttcttcg tcataatacg ttaatactat
    26221 ttcgtcttta tctatatatg taacaataca ttttctatca tgattaaatt tcacatcatg
    26281 caatctaata atttcgccta tttttatatt tttacttttt agtaatttca atctatccac
    26341 ctcttaattt cgaatattct gattctttca tatatatttt ttactttttt cttcttcaat
    26401 ttcaaaaaga tattcggtac ttaaatcagg gaagaatatt gtttgtattt tttttgcctc
    26461 aatatatttt agtctattaa tactatttaa cttggcgcaa attgtactta catttaaatt
    26521 taacgctttt gctatttttt catttgttat attttttctc gccatttctg cttttaaatt
    26581 tctaaacatt ttaatgctcc tttctgaatt tattcacgaa attgcgtgtc ttatatttca
    26641 tataatacac tcaatttcgt gaatagtcaa tatgtttttg tattttattt ttgcaatttc
    26701 gtaaattttt cttgaatttt tacgatttta ccattatatt aaaaacaagg tggtgattaa
    26761 atgaatatag aagaacgttt aaaacaatta atacttagca aatataaaag cataagagct
    26821 tttacaaaag aagttaatat tccttattct acagttgata ctatgcttaa gcgcggaata
    26881 agtggtacta gtataacaac agtattaaaa atttgtaacg ctttaaatat tgacgctgat
    26941 gctcttattg acaacgaact aaaagaaaaa gaactatctt caaagataca aacaaatcag
    27001 ttcgaacaaa aaattttaaa aatgtataat gctctcgatg aacatggaaa agatattgta
    27061 tttactatat tagaaaaaga atatgttaga attaataagc tctagtacta gagcttatat
    27121 tttgttctac actctaatat taacacggaa aaccattcca aaaatattcg tacgacgaat
    27181 attccgactt taatttacaa aatttaccaa ttaatttgtc tattttctaa attgtaaaaa
    27241 atttctattg attttaatat tttttaatac tatagtttaa tttcgacatg gagtctttat
    27301 taaaatatca tagaaaaaag aaaaaactca ctcaacgtcg attaagtgaa ttgacaggaa
    27361 taagtcaaag ttacatttca aggatggaaa acaaaaaatt taaacacagc ccaaccttaa
    27421 ctcaaataat tttattagct gatatattag aaattgacca attgatttta tctgaatttt
    27481 ttttggaaaa agaaagggag catttaaaaa atactaaaaa atataataaa aaagcagtta
    27541 aaacacttag cagggatttt ttaaaagaat ataaaaataa ggactaggta attatttata
    27601 cctagcccct ttttttactg ctctacttta atttctccta gctcaatcca gttatcttta
    27661 tataattccg gaaatttctt ttctacatct gattttgatg ctccttgatt tgcgtactcc
    27721 attgcttcaa aaagtcttga ataatctttc aggttatatt ttaaaactat ttcttttaca
    27781 ttcatattct tttcaactaa tattttaact tgtgcatcaa atttgtagtt agctggtact
    27841 tgttgattgt ctaatttatc agttactttt atgtctttaa attcgtaacc atctgtaccg
    27901 actgcgttcc atcctgtttg aaataattta actgctttat ctgttttatt ttctacttct
    27961 acatttacaa cttcgtacac ataatcagct gcctttttct tttcgattcc atcactaaaa
    28021 tattctccat tttcgttaaa acttccgtct tcgtttatat ctccttttat atcttctttt
    28081 gtaacatctt ttacagttat tttaattcca tcaacctcat tttcatttgc tttcttttct
    28141 tttttagttg tgtttccagt atctttgtta ttagttgatg aacaagcaac caaccctaca
    28201 cttaataaac atactgtaat taataataat acttttttca tcctcgattc ctccatgttt
    28261 ttatgttttg ttatatattt caacatcaaa acttatattc ctttaatttt ctattctagt
    28321 agtatgaaaa taatttaaaa gaataatacc tatttatttc cattctaagc atttttttat
    28381 gctatttaac ataaattatt tataacaaac agaaaaatcg tttctggtgt cttgtatcgc
    28441 ttctaaatga tattctagtt tcttaatcaa ataatcattt tctttttatc caaagataca
    28501 ttctaatagt ttctttactt ttgaaaaatg ctaataatat tttaaatagc gaccaccact
    28561 ttttgagaca agttagattt ctaattaagt taagtacttt aataaataaa tacaaaagat
    28621 acatattttg ttctctataa tacaagttct ctataataat atattctcta tatatttact
    28681 gcaccacttt ttgcactacc aaagcaccac tttttgcact accaaagcac cactttttgc
    28741 actaccaaag caccactttt tgcacgtagt aagaaatcta attaattttt aaaaacttat
    28801 taacatgtta tcaacataaa aataatggtt atcaacataa aaatcaaagt tataaacagc
    28861 attgttatat ttagacataa aaatagacct tttttaaaga aggtctattt tttacgtgca
    28921 tttttccatt ctgaaaaact acatagtcta tataattttt gtatcctagg aactttttta
    28981 ttcttttctt cgtcccactc aaatttattt tcttttttta cttcgatata tttgcttact
    29041 tcaaatactg ttataatttt tcttatttta cttctgttat ttttgctatc accacataac
    29101 ccgatttttt cacaaataaa tttttcagtc atacatttaa aactattttc agttgtcatg
    29161 taacataaaa ggcaataaac ttttattgca ttagtattaa atgcagaaat taattcttgt
    29221 agcatatcat gatgaattgt aacaaattta tgaacgttat cgttgtatcc tgtacttgta
    29281 ccatagttta atctataaat tattccgttg cggctgtttt ctatttcaag tactttacaa
    29341 tctaaactat tgagcttttt tatatttctc tctaaagtag tacgagcaac ccctatttgt
    29401 ttagctaatt cttccatttt aaatttattt tgatacaaat atctattttt ttctatatgc
    29461 ataattctca tgctcccttt acttataagc attaaagcgc caaactcttt agcacaataa
    29521 tttttttcat ttaaacaata cgtaggcatt ggtaatttat aatttttttc taattctttt
    29581 gcttcttcta aagacatttt atttccccct tttgacgggg cttgaagcac ttttaactaa
    29641 ttaagttaaa aatttcaaat tatttttaac cttaaaacat tgatttataa gttgttttaa
    29701 tctataatat aacttataaa ttagttaaaa aaggatataa ttatatccta taagagcttc
    29761 aagctccgtt ggtaaggaat aagtcgagtc gccaaacaaa cgcttattcc ttttatttgt
    29821 ttttgtaatc tgtaataagt taatattaat tatagcataa atataaaata aaaaaatata
    29881 ttgattttga aaataaatta tattttaaaa gacttagtac acttactaag tcttttttta
    29941 tgtaaatata tgttataata attttagcga ggaaaaaagt gattgaaaaa gcgtaagagt
    30001 ggctatttcc atatttaaac gccaaattcc ataacggaag gaggtggaac aatatggtga
    30061 taaatttttt attgagtata ctagctggtg ttatatcagc ttccatatat gataaaataa
    30121 aaaaccactc aaacgccaat aagagtggtt caagaaaata agttattttt caaaacattg
    30181 gaaatagcta ctcttgtgta aagtaaatca ttatttcctt gcttttatta tatcacattt
    30241 tttaaaaaag atacaatttt acatcacttc atatatgtta attagtttaa aaatacaaaa
    30301 ccactctgcg caaaagagtg gttgggaatt tgatttaaaa atcaaattca aaaagtctag
    30361 ataatttttt actttagacg aaaactctac tcttatgact gaaatacagt tctcttgctt
    30421 ttattatatc acattttctt taaaagatac gaatttatat catttctaat atactaaaat
    30481 ctttactttt taccaaaatt tgtttaaaaa taggagaaaa ctattgcttt tgacgccccg
    30541 tcatgatata atatatttat agagaaggag gtgagaaagc aaaaaaaaat aaaagaaagg
    30601 aggaacggga atggggagat tagaaagaag taaaaagaaa agagaaaaca aatttaacat
    30661 agttaaaaaa gttttctctt tcatcctatt attacttaac ataatcctcg cagttctaag
    30721 aattttaaaa gaactgtaag gataagccta gagggaatag cccttctctc taggtgactt
    30781 ctttctaata ttataacaca tttctaaaaa acatgagtga taaattttat aagatttgca
    30841 ttgttttagt tttgataact atagtcttaa atatagtatc tatagtatta aactctagta
    30901 caagcaacat gctcggttta gtttttagtg ttgtattatt gcttttcttt gtaatacagc
    30961 aaaaaaggag ctaatgaatg gaaaaagaaa aaagagattt aaagtttaac tttcacaaag
    31021 gtgggagtgg gtcgtttact cctagaatga gtgttcctaa aaaatgggct gatgaaatgg
    31081 gcataacaag agaaaaccct aatgttacgg caacattcga gggcgacagg ataataattg
    31141 aaaaggctaa gaatgaatga ctttttctat aaaagaaggt tgcttttttt cttagccttc
    31201 ttttttttaa attttactat aatataaaaa tattgctgta atattataaa aataatactg
    31261 taatattata aaaatattat tttagtattg tatatacaat attttagtat ttttaatata
    31321 atatattggt attgtaaaag caatatgtaa atattgtatt tatattattt gaatattgta
    31381 attaacaata ttaatatatt gttgcaatat tataaaaaca atactacaat attgttataa
    31441 tattataaat ataataatga ggtggagaaa atggctaata caaagctact tacgtacttt
    31501 aacataaaag gaggtatcta taagacaaca acgtctataa tgacagcgta tgaacttgcg
    31561 aaagataaag ataaaaaaat actcttatgg gacttagatg tacaagcaaa tctaacacaa
    31621 tatgtttatg aaataaatca taatgataat actacattag atattttaaa agggattagt
    31681 gctaatgatg caatagtcaa gtcacctaat gaaaagtaca ttaatgtaga cttaattcct
    31741 tctgacatac aaatggctag atttgaacaa gagctatcac ctttaccagc cagagaaaaa
    31801 tttttagctc gctggtacat gcaaaacttt aatactttga gtgagtatga ttatattatc
    31861 tgtgatttat ctccacgcta cgatttgaca gctaaaaatg tgcttttctt agcagatagt
    31921 ataattattc caattcaaga taaaaacatt tcttctttaa gaggagcaga attatttaaa
    31981 caactctggg atgttgatag aacctatttt gataaggagg ataatataaa aagtactgtt
    32041 ttggttggat ttgagaagaa gaaaactcaa attagtgata ctttcgattc ttatctggaa
    32101 gggtttaacg atatgagaga tattatgtta gatacatata ttagaaaaaa cgagtttata
    32161 gagaaggcac tattgaaaaa actatctcta acagattata caaaaataac taaagagcat
    32221 ttcagcagac aagagtttgc taatatgtta gaagaactaa aagtgaaagg agtgttgtag
    32281 atgccaaaat tcgacgaaga acttttatct aataaagaaa aaccagtttt caaaaaaaat
    32341 ggaacaatca tacaaaataa ttctacaact acagacaata agacattaaa catatataat
    32401 ctagttaata agaaaagtaa aaaggtaact atgagtgcaa cgcttgatga agaacttgta
    32461 aacaaattaa aatctttttc tattgatatg aacagcgacg tcagcaaatt attaagtgat
    32521 gtactaactc aaattttatc tgatgtcact ataaaagaag agaatttaaa tatatacaat
    32581 gagagaaata gaagaaataa gactaagaaa aagtaaataa tattatattt atattgttta
    32641 gatattactt aaatattgta tatataatat ttaagtaata ttttaatatt attattacaa
    32701 tatatcgata ttgtttaaat aatatgtttt aactataatc taaaaggggt tggaaaagat
    32761 gaatgtttat ttgcaaattg gaaaagagtt atctgaaaaa atgactaaat ctgaattaaa
    32821 taagttttcg caggaggtgg caaactatct gcaatacgct ggacttgata agaatatgaa
    32881 aattaaacta tttcaaacaa ttttggaaat ggtggcaagg aaaaaaataa cattatcaag
    32941 cgatagcgaa tttacggaag gaatattgca aagcgacgaa gcagaaatga caatgaacgt
    33001 aggatttata atcgaaggat taagttatca taataactaa acatttttaa aaaaacagtg
    33061 tatttattga atacactgtt tttatttccg catagttaat ctaaaattgg atattgtatc
    33121 atatggatat agattaaatt gatatttaaa tcccttatag ttaatcttaa aaattgttat
    33181 tatattattt ctctataaat taaattgaca tttaaatccc ttgtagttaa tataaaaatt
    33241 cttattacaa tatcatttct aaataaatta aaaaatattt taaatccctc gtagttaatc
    33301 ttaaaagcga tactatatac attaataata atactcttct acttaatttt caactatatt
    33361 ttgtaattct tgtttacaac tttcaatgcc ttctcgtaat tcttctaaaa aaaactgatg
    33421 tgctatcgtc tatatttctt tcagcaattt cttcaaaatt ttctttattg aattttttat
    33481 aactatccca attcaaactt tcgcatttat tttcgcacca attttcaaat tcttcgtaat
    33541 catttacgta gtaaatttct ccaaacatat cgtctaagtt atttcctgtt tgtcttgatg
    33601 tgaaaatatt aatttcttta tcatcatcta aaagtttagc ataagcctgg attgctatcg
    33661 cttcaacttt tccttgtata tcgatataaa tttttatatc attagtctct ttgattaaac
    33721 aactttcttt aaaagctttt atagcttctt cctctatttt atctatattc atatctataa
    33781 cctttaaaaa ttttttagct tcttttttat ccattttatc cattttaatt tcctccattt
    33841 tttagttatt ttttatatat aacagttctt tcgctctttt caatttctgt aagatactct
    33901 aaaaattctt taatttcttg cttgtttatg cctataaatt cgtgtctaat ttcacatttt
    33961 tcaatacgtg tagaatattt ctcttctaat ttataaaatt taggtcttac attggctata
    34021 aggtcacttt ctacattttt gctacacaag ctatttacat atattaaaat gttttctata
    34081 ttttctatgt ctactttgtc gccttttgaa taataaaaat taaatctcaa tcttattcct
    34141 attttactgt taatttcacc atgaccccac gtttcaatgt ttaaactttt tccaactgtt
    34201 tctttaacgc ttccaatgtg accgttcgca caatctttaa gacttatatc aaatatatca
    34261 ttgttgattt tattaatctc tttttctatc attttaacat tctctttatt aacttttaaa
    34321 tctaatattg tactaaaatc tatattcatg ttttaaacct ccaattattt tttattttaa
    34381 ttatagcatt caatggtgaa ctatatttgt atcaagttga aacttttaac actctacgcc
    34441 atctctgaat acttggtatg caatttctat ttttctttca tcactttcta tttttctata
    34501 gttttcaatc tgcttctttt taatgtctgc aaatccattt ctataaaatt gtgcattttt
    34561 ttgtattaat gtttctatta tgtatttttt agctttctct atatattctg tgctagtagc
    34621 ttgttttact gcgtcgtcaa atatttcaac tatttcaagt acattttctt ttatttcatt
    34681 agaccaatta tcattaaaat ttatttcttt agctattttc ttagcttctt catagcttat
    34741 actataatct ttaacttttt taagtctata agatgcttgt gtctcccctt gtaaaaaact
    34801 ccaatttctg ttctcttttg caaattgaga atcttttaat atctgattta tatgaaatgc
    34861 tttttgattt aaagaattat actttaaaac atttctaaaa ttatctataa agaacttagc
    34921 attctctata ttgcttattg cttctcttat tctttcaaat tttcttttac atctttctgt
    34981 catttcttct atactcatgt ctttaatttt gtagtcttca ttttttattc tttctatttt
    35041 acttttttct agttcgttag ttaaatttaa aatgtctgtt cttatatcat tagcccaaat
    35101 aatttgtttt tctgaccctt ttaattcttt caattttata tccccctttt tatttaagaa
    35161 tgataagcaa agactaaatt gtactttata atctacatta ctatattttc tttttatttc
    35221 tcttgccatt ttatgcgctt ctttaaataa aattttcatt ctttgcttac ccccttgttt
    35281 tatttgttaa ttatattata atctatatga atatctaagt caacactttt tcaaagtttt
    35341 ttctttgatt tccaaaaata taactttgat tagcgtagat tattctttta cttttaattt
    35401 ttttatgtta ttatataaat aagagaggtg cgaaaaaatg acatggaaga atgaaattaa
    35461 aagtattctt gtaaaagaaa atatcagcat gaatgagtta aataatttaa tgaatgaaca
    35521 taataataag aataatacag ttgaaaattt aagacaaaaa ataaataatg agactatgaa
    35581 gtatagtgaa atcttgacta ttgctaattt gataggatat gaagttgttt ggaaaaagaa
    35641 agaaaagtag acataaaaaa agaaggtaac aactaactag ttgctacctt ctaatctatc
    35701 tatcaataaa atctaatgct ttgtaaagtg tttcaaacct atcattacct tttatcatag
    35761 tataattttc tttagtcata gaacttatct tttcacatgc tccaccacca acaacataaa
    35821 gattttgtgt ctggccaggt acataatctt ttatatcaca tattaatatt ttcccatcat
    35881 tataacccca tccaacaaca gttgcaggga ttttgtcaac ttctccatca taaatgattg
    35941 tatgtttgta catctgttta actccctcat tatttatatt tttatttaat acaccttcta
    36001 caatcaactt agcaatacct tcatgaccta gtttcttagc tttctcataa tcttctttgt
    36061 tatcgcaaaa gaaactttca attagtattg cagtaggttt agaactattt aaaatatata
    36121 aacttttatc taatttaaca cctctattac ctacttcttt atctcctttt tttcttatga
    36181 aaggtttaga taatttatct actacccttt gcgcatattc cttccctttt tcactatagt
    36241 aaaatacttc tgttccaaag gctcctacac cacttgaatt taaatgcaac tctataagta
    36301 agtcatatcc tccactatta actttaggta ttttgtaaga tttttcctca ctcttagttt
    36361 taaactgctt ttcggggcat attattacat ctgccttatg accttctttt ctaaaagtat
    36421 ctgctaatac tggtgcaaga gatttattgt attgatactc gttaactact ccattagcag
    36481 aagtacatgc cccgcttttt aaaatgctgt gtcctactgt tatacatatt ttcattattt
    36541 actacctcct ttaacattta attcatctgt catagtatct aataaactac ctattctatc
    36601 ttttaatttt ctaggtactg gtaacccaca caaatacatg ttttttaata tacttacact
    36661 ttcatataga ataaataaaa tagagaaaaa ttcagatatt ccaagatgat ttaatcgcaa
    36721 aaaatcaacc caatcttgtg gtaacataaa taaaaagtta aactttgtaa gaatgtcaac
    36781 tactgctaga aaaaatatac atgctatcat tgcaactttt cttattcctc catttattcc
    36841 aaaacttgaa ttaaactgat gtgtttttat tgctcttaaa caacctagca atgtatcaaa
    36901 tgctattgct aatattacta attttataaa tatatttgtc gctaaaaaaa ctattgttac
    36961 gttcatattt cctccttatt ttgcattaaa ataagactta g
//
LOCUS       DAFAZV010000043        36658 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFAZV010000043 DAFAZV010000000
VERSION     DAFAZV010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 36658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36658
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.043"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            41..691
                     /locus_tag="KOU88_002889"
     CDS             41..691
                     /locus_tag="KOU88_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HBK3212751.1"
                     /translation="MKAEKTSIYPIIKNNLNKISIVEYKKGQRFVASDKDLQEVFFII
                     EGVALVECTTRGGNKFLVDIVPENEFIGKISYIYEHNLKCDIFAKTNIKLFRFEKNVF
                     EEFYLKPDFIALFHRKCTRRIYELYKTRMVRELFSCTEVIAYCISNKQENNVCNIKAI
                     RNFSEIYSISRKSRYHSLLKLTEKEIVKKMGNTYEILNYDELHKLAFEVKEFLEDE"
     gene            complement(831..2207)
                     /locus_tag="KOU88_002890"
     CDS             complement(831..2207)
                     /locus_tag="KOU88_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3212752.1"
                     /translation="MQELFSLKDENKRFYKILLSLCIPIIIQNLISTSVNVIDTIMIS
                     SLGETSVASVGVANQFFFLFNMSLSGITGGAGVFISQFYGKKDVSNIRKVTGLTCVLA
                     IVLSFVFVIPALLTPKPIIHIFSYDSEVVKLCIDYFSIAVFSYPLIAVSTVFSTGSRG
                     VRNPKLGMICSAFALVTNVILNYGFIFGNFGLPALGVKGAALATVIARICELILMITY
                     VYLYKKDYILKFGLKNLKAIDKIFIKSFSSKSFPIFVNDSVWAIGTVLYSVAYARAGT
                     SAIAASQIATSTGNFFIMTAVCIASGASIMLGNELGADHIKRAIEYAKKFSILVFSAG
                     LILGIILILNIPLLLKMFSVSDSLASDITKIFFIMGILMALKSFNTLVIIGILRSGGD
                     TKYALFLELGCMWLASIPLTFIAAFKGAPIFVLVLLTYSEEVVKFIFGVPRALSKKWA
                     INIVKEID"
     gene            complement(2223..4136)
                     /locus_tag="KOU88_002891"
     CDS             complement(2223..4136)
                     /locus_tag="KOU88_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK3212753.1"
                     /translation="MIVLSCNNLNKSFGIDSILENISFTVNEGDKIGIIGVNGTGKTT
                     LFKIISGIYGYDSGDIYTSKDCEIGYLEQNTNFYSDNTILEEVLEVFKNLIEMESYLR
                     ELEVKISEESTKTNSPIIEKIMDEYSHKLELFSDLNGYGYKSEAKGVLKGLGFSDNDM
                     DKPISILSGGEKTRVLLGKLLLKKPTLLLLDEPTNHLDSEAIEWLEVFLKQYKGTVML
                     ISHDRYFLDQSVNRIFEVHNKKLKVYNGNYSKFVELSKIEKELELKKFEDQQKEIKKQ
                     EESIERLKAYGREKHLKRARSKEKALDKVDVLDKPEAYRKKARIQFTPSVQSGNDVLQ
                     IRDVSMGYGERILFKDLDLDIYRGEKVALIGANGVGKSTLFKIITNELQPLSGNIKFG
                     TNVHVSYFHQEQKTLNLDNTIIDEIWENNTHLTQTTLRNMLGAFLFVDEEVFKKISTL
                     SGGERARVAILKLILSNANLLLLDEPTNHLDIDSKEVLEEALTNYDGTIFTISHDRYF
                     LNTVVDKILVLDENGITEYLGNYDYYIDKKRQIQEMSIIEEKEEKTRTQIKDEKRKER
                     EQREIEKKNRIKRQNIEKEIEKLEIEIEKLDILLCQEEVYSNPDKAKEVSQEKINLEN
                     NLASLYDEWEEFM"
     gene            4272..4904
                     /locus_tag="KOU88_002892"
     CDS             4272..4904
                     /locus_tag="KOU88_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBK3212754.1"
                     /translation="MLGNKNISMAVIRRLPKYHRYLGDLLDRDIQRISSKELSDIIGF
                     TASQIRQDLNNFGGFGQQGYGYNVEALHTEIGKILGLDRPYNAVLVGAGNLGQAIANY
                     AGFRKAGFEIKALFDANPRMIGLKIREFEVLDSDTLEDFIKNNNIDIAVLCIPKNGAQ
                     EVINRVVKAGIKGVWNFAPLDLEVPKGVIVENVNLTESLFTLSYLMKEGK"
     gene            5043..5582
                     /locus_tag="KOU88_002893"
     CDS             5043..5582
                     /locus_tag="KOU88_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA C4-type zinc finger protein"
                     /protein_id="HBK3212755.1"
                     /translation="MVFVEELWKKAIKFHGHECPGLAIGFKAALAAREYLGCKQSGDE
                     EIVCISENDACGIDGIQVVLSCTMGKGNLLLRMTGKSVYHFFNRENGKSIRIYVKSKP
                     FQMDREGYKKYLLESDFEEIFEITDTKLRLPEKARIFKSLKCEVCGEFASEQYIRIEE
                     GKKVCLDCFNKYERFYEEY"
     gene            complement(5758..5928)
                     /locus_tag="KOU88_002894"
     CDS             complement(5758..5928)
                     /locus_tag="KOU88_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004619190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3212756.1"
                     /translation="MAYKITDACISCGACEAECPVSCISAGDDAYVIDAGSCIDCGSC
                     AGACPVDAPQPE"
     gene            6213..7280
                     /locus_tag="KOU88_002895"
     CDS             6213..7280
                     /locus_tag="KOU88_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HBK3212757.1"
                     /translation="MKNKLVYICIMSLLLFVVGCSNNPNKESTIKKDSKNNQSQVKEE
                     KREPVKKDITISFAGDVTMGNYKGSSYYGSFDHEFKRQGEDYNYFLKNVKPVFEKDDL
                     TVVNLEGPLTTASNAKEKKFAFKGKPGYVNILKSGSVEAVSIANNHSEDYFEEGMKDT
                     QFILDENKINYFGLGKDAVVDVKGIKVGLLGYNGLSTEYNEKNLKQMEDDIKSLKKKS
                     DVVVVYFHWGIELDYYPDKKQKDFAHYAIDKGADLVMGSHPHVIQGIEKYKNKYIAYS
                     LGNFCFGGNKNPSDTDSYIYQQTFTFSDNKLTSIKEPNIIPTSITSSNSRNNYQPKIL
                     DGSEKDRVLNKLEKISKDLNK"
     gene            7450..9351
                     /gene="cooS"
                     /locus_tag="KOU88_002896"
     CDS             7450..9351
                     /gene="cooS"
                     /locus_tag="KOU88_002896"
                     /EC_number="1.2.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic carbon-monoxide dehydrogenase
                     catalytic subunit"
                     /protein_id="HBK3212758.1"
                     /translation="MACNTCKMCESADKKLESFVASKDVETAFHRTEDQKVKCGFGLQ
                     GVCCRLCSNGPCRVTPKSPRGICGADADTIVARNFLRAVASGAACYLHVVENTAKNLK
                     NVGITKGVVKGEKTLNQLAEMFGIESDEKYDKCIKVADKVINDLYKSRDDKMELVEKI
                     AYAPRVKKWKELGIMPGGAKSEVFDAIVKSSTNLNSDPVDMLVNCLNLGISTGLYGLT
                     LTNLLNDVMLGEPVIRMAPVGFNVIDPDYINIMITGHQHSTFANFQDRLKDEDVIKLA
                     QSVGAKGFKLVGCTCVGQDLQLRGEHYQEVFAGHAGNNFTSEAVLSTGAIDIVLSEFN
                     CTIPGLEPIADKYKVKMVCLDDVAKKANAEYIGLDRSKLDELSNTLIEKALESYKERR
                     GSIEIDIPKDHGFEQSLTGVSEKNLKAFLGDSWKPLINLIAEGKIKGVAAVVGCSNMT
                     AGGHDVNTVELTKELIKKDIIVLSAGCSTGGLENVGLMSPGAEELAGENLKEVCKTLG
                     IPPVLNFGPCLAIGRLEIVATELAAELGIDLPQLPLVLSAPQWLEEQALADGAFGLAL
                     GLPLHLALPPFITGGKLVTEVLTEKLKDLTGGHVIVNPDPKSSANQLEEIIIDRRKNL
                     GLKDVECNA"
     gene            9344..9817
                     /locus_tag="KOU88_002897"
     CDS             9344..9817
                     /locus_tag="KOU88_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBK3212759.1"
                     /translation="MHRIFINKDLCTGCKSCVLACMLKHNKDYDMYTLDLENIDNDSR
                     GHIELDSRHNNPVPILCRHCDEPECVLACMSGAMHKDSESGIVSYDEEKCGSCYMCVM
                     SCPYGLLKPDDRSKQNILKCDLCKDEEYPRCVANCPSGAIELQKEENDELCSVRG"
     gene            9792..11018
                     /locus_tag="KOU88_002898"
     CDS             9792..11018
                     /locus_tag="KOU88_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK3212760.1"
                     /translation="MNYVVLGASAAGINAVKTLRELDKDSNIVVISKDENVYSRCMLH
                     HVISEHRTLKQINFVDEDFMEQNNVKWIAGKTVKGIDINKKVVQTEDITVNYDKLLIA
                     TGASSAIPPIKNLRDGNFVYSVRNIDDIYKIKEKAQNSKNVVIIGAGLVGIDALVGLF
                     KYEQLNISVAFMEKYILDRQLDEYTASVYENKFKEKGVKFYPSASIQEIVLDNSKNVT
                     GVAFSNGEVLDADMVIVATGVKPNADFLDGTGIEYDRGIIIDDMCQTTQKDIYAAGDV
                     VGKNAIWPLAVKQGIVAAYNMVGKDKKIEDEFAFKNSMNFMDIPTISIGMNTPVDDSY
                     KVLTRHGINDYKKFVFKDNVIYGAVIQGDISYVGVLTYLIKNKVEIYDLENRIFDVCY
                     ADFFNIKENGEFCYSV"
     gene            complement(11157..12344)
                     /locus_tag="KOU88_002899"
     CDS             complement(11157..12344)
                     /locus_tag="KOU88_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK3212761.1"
                     /translation="MNITKNFLKDYLERFGETPFLVRLKDEEEFLIGEGSPQFKVIVN
                     NDISKSELLKSTSLALGEAYINRDIEVEGDLFLTLNLLLKQIDKFNIDNSAVKHLLHS
                     SNSMRHQKKEIHAHYDIGNDFYSLWLDKTLSYSCAYFRNDNDTLYDAQVNKVHHILTK
                     LNLEEGMSLLDIGCGWGFLLIEAAKKYKIHGVGITLSEEQFKEFNTRIKEENLQDYLE
                     VRLMDYRELKKSDLMFDRVVSVGMLEHVGRENYELFIKNVNAVLKDGGLFLLHYISGL
                     QESYGDPWIKKYIFPGGVIPSLREMIHICSDYKYHTIDVESLRLHYVKTLLYWQKNFS
                     ENLPKIKEMFDDKFIRMWDLYLCSCAAAFNTGIIDIHQILFTKGIKNDLPLTREYMYN
                     CSK"
     gene            12617..13441
                     /locus_tag="KOU88_002900"
     CDS             12617..13441
                     /locus_tag="KOU88_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3212762.1"
                     /translation="MEVYALVGSSGTGKSFKALEFAYENDIEYIIDDGILIYKNKVLA
                     GISAKQANTTIEAVKRAIFYNLEHRQEVREAIKKENIRKILIIGTSKKMVNQIVERLS
                     IGRVCKFINIQDISTKYEIEIAKQARKEGNHVIPVPAVEIKSMASGLSINSLKRLFRK
                     GNNMNMVVLEKTIIRPTFSYIGKFYISADVIKQIIEYEVYNFGSIDRINKINIENCNN
                     FMNIFVSININDLETIKKIEDIQQTIKKSIEKMTLVNVQKIDINIHKIKKINFLQC"
     gene            13570..14835
                     /gene="gluD"
                     /locus_tag="KOU88_002901"
     CDS             13570..14835
                     /gene="gluD"
                     /locus_tag="KOU88_002901"
                     /EC_number="1.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-specific glutamate dehydrogenase"
                     /protein_id="HBK3212763.1"
                     /translation="MSGKDVNVFEMAQSQVKNACDKLGMEPAVYELLKEPMRVIEVSI
                     PVKMDDGSIKTFKGFRSQHNDAVGPTKGGIRFHQNVSRDEVKALSIWMTFKCSVTGIP
                     YGGGKGGIIVDPSTLSQGELERLSRGYIDGIYKLIGEKVDVPAPDVNTNGQIMSWMVD
                     EYNKLTGQSSIGVITGKPVEFGGSLGRTAATGFGVAVTAREAAAKLGIDMKKAKIAVQ
                     GIGNVGSYTVLNCEKLGGTVVAMAEWCKSEGSYAIYNENGLDGQAMLDYMKEHGNLLN
                     FPGAKRISLEEFWASDVDIVIPAALENSITKEVAESIKAKLVCEAANGPTTPEADEVF
                     AERGIVLTPDILTNAGGVTVSYFEWVQNLYGYYWSEEEVEQKEEIAMVKAFESIWKIK
                     EEYNVTMREAAYMHSIKKVAEAMKLRGWY"
     gene            15048..15638
                     /locus_tag="KOU88_002902"
     CDS             15048..15638
                     /locus_tag="KOU88_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBK3212764.1"
                     /translation="MHFKSKDLNLKYLVLFLKIVYWFNPFIYIMEKYMDLDCELYCDE
                     RVLKNCTVQQKQEYALTIVNSMKRGTNFSNKFVAGLNKQSDIRKRVINMFSEKHKNGI
                     LMALIISLFSSITFFKFDSTSIIEENDFLERLRYTFEGRQEDMFVTIDFTYADAPIKL
                     RKEHEENCRVNGIVPKDSDSIEIIPRFYKDCMDLKK"
     gene            15968..17101
                     /locus_tag="KOU88_002903"
     CDS             15968..17101
                     /locus_tag="KOU88_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M56"
                     /protein_id="HBK3212765.1"
                     /translation="MSNFILNGIFRTVIVSSLSILLILIFKKNVFKRFSKKFNYYIWM
                     IVVIKLFLPFTYYTFTINILRSKKHININNINLEGFNNVSTISNNIILYTWIITVVVY
                     LIYTIFKYIKLKNLINDLSYDVDDREIVNLYKNILEEFNITKDIKLKYSYEVETPAFF
                     NSCVLLPPHEYKLKELDWIFRHELMHFKSRDLYLKYVILFLKTVYWFNPFIYIMDKHI
                     DLDCELYCDERVLKNRNSEEKKDYALTILNAMRKGSNTSNKFIAGLHKQSDIKKRVMN
                     MFNEKYKNGILMALTLCLLSSITFLKVNSTSIVNLNILPKGMEEKDVTNSAIVTMIEF
                     TYAEAPKSMREEHKINCEFLGLIPKDSDKIGVGIEYYDSLLND"
     gene            18017..19066
                     /locus_tag="KOU88_002904"
     CDS             18017..19066
                     /locus_tag="KOU88_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK3212766.1"
                     /translation="MKKKILIPVFASVMALSVSSIVNADEVNDSSQNKDDKTNTELNL
                     GEYKEVKYKVAKIKDGVAIKIREEGQVQNIAYSGDEFTVLGTQGEWVKVKVEDGEGWL
                     ATRYVDISEGVGYTNADKVNLRKDKSESSEVIEELEKGSSLLVLEDNGDWLKVKDGET
                     EGYVKSSYISDKAPVIEEPQVNPSVNQNGDSTNNNNQQNNANNIQQDNTNDNQQNNNS
                     NVPTANSNAVQAVLNLAYSKQGCPYVWGAEGPNTFDCSGFTQYVYRNAVGKNIPRTSK
                     AQSKYGQTVSKANLQPGDLVFFTTNGSGSVSHVGIYVGGGNMIHSPSTGKTVSVTSIN
                     SSYYTARFVTAKRIL"
     gene            19362..20282
                     /gene="pyrB"
                     /locus_tag="KOU88_002905"
     CDS             19362..20282
                     /gene="pyrB"
                     /locus_tag="KOU88_002905"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBK3212767.1"
                     /translation="MLKSRNLIQPEDFSIEEIDEILELAQKIIDNPSKYSRICEGKLL
                     ATLFYEPSTRTRLSFESAMNRLGGRVVGFSEPNSSSASKGETLGDTMRIVSGYVDIIA
                     MRHPQSGAASEAARYTEVPFINAGDGKNQHPTQTLTDLLTIKSLKGTLESHTIGLCGD
                     LKYGRTVHSLVKAMARYKNTKFVFIAPEELKMPDYIKEAIKGHAYYETNNLDDVIGSL
                     DVLYMTRVQQERFEDKSEYERLKNYYILNKAKLEKASKDMLVMHPLPRVNEIDIDVDS
                     DDRAVYFKQAKYGMYVRMALIIKLLGINED"
     gene            20321..21013
                     /locus_tag="KOU88_002906"
     CDS             20321..21013
                     /locus_tag="KOU88_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBK3212768.1"
                     /translation="MYKILENIYIGEDMYRMKVKGNFEGKMGQFYMLRAWDTYPVLSR
                     PISIHDIDEEGITFLYKVVGEGTQILSNLKVNDTIKLEGPYGNGYAKVDGKVALVGGG
                     IGVAPLYLVAKNIKNCDAYLGFREDVILEDEYKQVCNKVYTTVGNTFVTDIIDVEKYD
                     YILTCGPTPMMEKLVKMVEGTKTRIMVSLENHMACGVGACLVCTCKTNGGNKKTCKDG
                     PVFWGEDVIFNG"
     gene            21006..21908
                     /locus_tag="KOU88_002907"
     CDS             21006..21908
                     /locus_tag="KOU88_002907"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBK3212769.1"
                     /translation="MGNLSVKFGSVEFKNPVIMASGTFGFGKEYNEIYDIQKLGGISS
                     KGLTLNKKPGNNGMRVHETPSGMMNSVGLENPGVQGFIDYELPFFSKLDLVRIANVGG
                     GTLEDYLLGVQMLNDKPIDIIELNISCPNVKAGGMAFGIKNEVAREVVREVRNITKLP
                     LVIKLSPNAEDIVGMAKVCEEEGADGVSLVNTFKAMAIDIKSRRPVFENVYAGLSGPA
                     IKPIALRMVHEVCKNVNIPVMGMGGITKATDAIEFIMAGATCIQVGTANFMNPRIGIE
                     IIDGINEFMDREGIKSLDEIRGII"
     gene            21993..22577
                     /locus_tag="KOU88_002908"
     CDS             21993..22577
                     /locus_tag="KOU88_002908"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBK3212770.1"
                     /translation="MSKVDVVDILKKSDALLEGHFLLSSGKHSNRYVQCAKVLRFPEY
                     AAEVLSTVVEQIKDLDIDLVVGPAMGGVIVSYELGRQLGKEAVFTERKDNTMELRRGF
                     EVKKGAKIIIAEDVVTTGKSTMETKRVLEALGGEVVGVACIADRTNHDIGMPIYSAIK
                     LDIQVYESDECPLCKEGKLPVVKPGSREFKELGM"
     gene            22792..23718
                     /locus_tag="KOU88_002909"
     CDS             22792..23718
                     /locus_tag="KOU88_002909"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBK3212771.1"
                     /translation="MKNQLNENHKKVVFFGVGAVGATFAEQFFNSKYDFKILCDNERK
                     KRYLEEGFIINGKRYDFDYVTKDEYKQEADFIIIGLKYNNLKENIKELDGLVGKNTVI
                     MSLLNGVDSEEIIGERFGIEKMVYSYVTNIDAKKINNNIIHTTNGIIVFGNKDNSEDR
                     KTNIITKVFDDVNIEYTLSKDIQRDMWWKYMVNIGVNQTSAILGAPYGVFQSSEHLRE
                     LAKSAMREVVAIAQAKDISLTEDDVEHSLHRILEHSKEGRTSMLQDVEAHRLTEVDMF
                     SKNICKLGKKYNIPTPINQTFFYMIKVIESRF"
     gene            complement(23770..24660)
                     /locus_tag="KOU88_002910"
     CDS             complement(23770..24660)
                     /locus_tag="KOU88_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3212772.1"
                     /translation="MFEELKTFVAVVEYKNFTKAGEYLNLSQPSVSKHIKNLENYFKV
                     VLINRSIKQKTIFITESGQILYKRAKEILNLLNITYHDVSQVSDAITGHLKIGASLTI
                     GEYILPNFLALFSKKYPDIDVEVFIKNTSIVSSHVKDYILDIGLIEGTCSSPSFIQEY
                     FFEDKMVLALPYKSHLLKDFSFDKLQNQKWIVREDGSGTRDYLDMFLSVKEIIPKSMM
                     VFGSNYAVKESVRNNLGITIVSNLVTSLPVLNNELSVIELGSSYNRHFSYIFPKDITL
                     SKAATIFIEELKIFSNLNSI"
     gene            24848..25879
                     /locus_tag="KOU88_002911"
     CDS             24848..25879
                     /locus_tag="KOU88_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBK3212773.1"
                     /translation="MLKKKSSLTLKTIREILPGLFVSVLVGYISIFISILIPKVGAAS
                     ISIFLGMFVGNLFLNQKVFQKGYKFSETDLLSYSIVLLGATLSVSTLIDLKVSGILFI
                     ILQMTITIIAALYIGKKLGFEENFRFLMASGNAVCGSSAIGATVPVVNATDKEKGIAV
                     TIVNVTGIFLMFLLPIISQFLYSHELVKTSAMIGGTLQSIGQVVASGAIVGENVKDLA
                     TIFKIVRVIFLVVVVLVFGHMKNQSNREILEEEKDEIKKKKVTIPWYVIGFFITCALF
                     SMNIIPQEVSVLCKEISNKLEIIALAAIGLKVNVKDLVKQGKEVSLYGLFVGTVQVVS
                     AVVLIKIFI"
     gene            26173..27048
                     /locus_tag="KOU88_002912"
     CDS             26173..27048
                     /locus_tag="KOU88_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxoguanine DNA glycosylase"
                     /protein_id="HBK3212774.1"
                     /translation="MNVYEKGNGVILEGVTDFDPVHIFECGQCFRWHKQEDGSYTGVA
                     KGRILNVKKENDKIYLNNTNLKEFNSIWYNYFDLGTDYAEIKNKLKNMDEYLNKATEF
                     GWGIRILRQDGWEMLISFIISSNNRIPMIQRAIENLSRKFGKYIGEYEGNEYYAFPTP
                     EELNKASQEEIRACQTGFRDKYIKSTTQAVIENNDEVSEYTNLSTEDCRKELLKFNGV
                     GPKVCDCIALFGMQKYDSFPVDVWVKRVMQEFYIDEDMSLPKMRTYGIDKFKEMSGFA
                     QQYLFYYARELGIGK"
     gene            27066..28556
                     /gene="cls"
                     /locus_tag="KOU88_002913"
     CDS             27066..28556
                     /gene="cls"
                     /locus_tag="KOU88_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBK3212775.1"
                     /translation="MGVIGTIFLFYLIISYLAGAIISVIILLENRDPAKTMSWLLMFI
                     IFPGVGLMIYAISGRNIRKRKLFKTQKLANNIKEKKLFDTLEKITEIVELEKESIKQN
                     KLLRDEEDGSYRKRVINMLLKTGMFPFTKNNKVDVFVDGNEKFKRLIEDIREAKDHIH
                     LEYFIIKDSEIGRVLKEELIKKAKEGIKIRILYDDVGCWRFWFNRKFFREMREVGIEI
                     AAFLPTKFPIIGGKLNYRNHRKIVVIDGIIGYTGGINIGDEYLGKNDKFGYWRDTHIR
                     IKGISVYMLQMTFLIDWYYTTKEVLVTKNYFPSVGNVGESMIQVVASGPDSDWEDIHY
                     AYFSAICQARKNVYIETPYFIPDESLLKAIKSAALSGVDVRIIFPKIADHKIVNIASY
                     SYFEEILRAGGKVYLYNKGFIHSKVVIIDDKIASAGTANMDLRSFMLNFEVNAFIYDE
                     EVIRVMTDDFFEDLSHCEELNLEVFKNRNIIQKIKESVARLFSPIL"
     gene            28749..29033
                     /locus_tag="KOU88_002914"
     CDS             28749..29033
                     /locus_tag="KOU88_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012062101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBK3212776.1"
                     /translation="MKIRPLADRVVIKKVEAEEKTASGIVLPGAAKEQPQIAEVVEVG
                     PGGIVEGKEIKMELTVGDKVIFQKYSGTEVKIEGQEYTILRQSDVLAVIE"
     gene            29066..30694
                     /gene="groL"
                     /locus_tag="KOU88_002915"
     CDS             29066..30694
                     /gene="groL"
                     /locus_tag="KOU88_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729227.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBK3212777.1"
                     /translation="MAKEIKFSEETRRALEAGVNKLADTVKVTLGPKGRNVILDKKFG
                     SPLITNDGVTIAKEIELEDRFENMGAQLVKEVATKTNDVAGDGTTTATVLAQAIIREG
                     LKNVTAGANPILLRKGIQKAVTVAVEELKNQSRIVETQEAISQVASISAGDEEVGKLI
                     AEAMEIVGKDGVITVEESQTMNTELDAVEGMQFDRGFVSAYMVTDVDKMEAVLNDPYI
                     LITDKKISNIQELLPVLEQIVQQGKKLLIIAEDVEGEALSTLVVNKLRGTFDVVAVKA
                     PGFGDRRKEMLQDIAILTGAQVISEELGYDLKEADLSMLGRASSVKVTKESTTIVDGS
                     GDKKAIEDRVTQIKHQVEQTTSDFDREKLMERLAKLAGGVAVVKVGAATEVELKERKL
                     RIEDALNATRAAVEEGIVAGGGTAFVSVIPAIGTLIESLEGEVKLGAQIVKKALEEPL
                     RQIAINAGLEGAVIVQNVVNSEAETGFDALNEKYVNMIEAGIVDPTKVSRSALQNAAS
                     IASTFLTTEAAVADLPEKEDAGMPGMGGGMPGMM"
     gene            30956..31696
                     /gene="larB"
                     /locus_tag="KOU88_002916"
     CDS             30956..31696
                     /gene="larB"
                     /locus_tag="KOU88_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarB"
                     /protein_id="HBK3212778.1"
                     /translation="MDLRKLLEEVKNENIDIDFALEKLKDLPYEDLGYANIDHHRELR
                     NGYPEVIYCEGKSDEHILGIIDKMNQKSSNILGTRCRKETFLKIKEIYNHAEYEEASK
                     ILKIQNHDIENIGKGKIVIATGGTSDIPVADEAYHTAKFLGNDVDRIYDVGVAGIHRL
                     LNKRHKIDSARVIVAVAGMEGALASVIGGLVDVPVIAVPTSVGYGANFGGLAALLAML
                     NSCASGISVVNIDNGFGAGYLASMINKL"
     gene            31780..32514
                     /gene="larC"
                     /locus_tag="KOU88_002917"
     CDS             31780..32514
                     /gene="larC"
                     /locus_tag="KOU88_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel pincer cofactor biosynthesis protein
                     LarC"
                     /protein_id="HBK3212779.1"
                     /translation="MSEKILYFDIISGISGDMTLASLLNLGVPKEIFLEEIHKLRMSD
                     EFNINISSKTENGIVGTKVEVITKEKHTHRNLVDIFEVIDKSTLNENVKSKAKKIFMV
                     IGEAEAKVHGTTIDKIHFHEVGAIDSIVDIVGASILVDLLCVDKVCASTVSVGSGFVK
                     CEHGIIPIPAPATIEILKGVPIKLNNVNGECTTPTGAAIIKVLCDEFVDELEFSPKQI
                     GYGIGHKKFEVPNILRTVLGEKKKKN"
     gene            32544..32963
                     /locus_tag="KOU88_002918"
     CDS             32544..32963
                     /locus_tag="KOU88_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF111 family protein"
                     /protein_id="HBK3212780.1"
                     /translation="MSSEIYSYLYEKILDEKALDIYTESIYMKKNRPATKVSILCNES
                     DLEKFIKILLLETSTFGVRYNAYNREILDRKFVKLDTKYGVVTVKLGYYKGKLVKATP
                     EYNECKTIAKNEDIPIKKVFADINFRIKEEFSENLLT"
     regulatory      33023..33124
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            33345..34880
                     /gene="guaA"
                     /locus_tag="KOU88_002919"
     CDS             33345..34880
                     /gene="guaA"
                     /locus_tag="KOU88_002919"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBK3212781.1"
                     /translation="MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKE
                     KNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILGICYGIQIMSHVLGGVVRKGNKQ
                     EKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE
                     RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKA
                     LCALSGGVDSSVAAVLIHKAIGDNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRV
                     NAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFLVQGTIYPDVIESGH
                     GNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGP
                     GLGIRVIGDVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDER
                     TYAYLVGLRAVTSSDGMTSDWYKMPYDVLERISNRIINEVDGVNRVVYDITSKPPGTI
                     EWE"
     gene            complement(34957..36003)
                     /locus_tag="KOU88_002920"
     CDS             complement(34957..36003)
                     /locus_tag="KOU88_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK3212782.1"
                     /translation="MPAYKDEQRKSWYASFYFTDFDGDRKKKIKRGFKTKKEALEFER
                     EFLNKSKMSTDMSFESLIEEYMHDMSSRLKLSTLETKKYLINFRILPFFKSLKINEIT
                     ATHIRRWQNELLKSDYSQTYIKTINNQLVAVLNYAVKYYNLPSNPAHLAGSIGKKNAD
                     EMNFWTLEEFKKFIEFEKKSEPRLAFEILFWTGLRLGELLALTPKDIFENKISVEKSY
                     IRLNGEDIVSSPKTPKSKRVVPIPHFLYNNIKDYLSKLYDLKDNERIFKFAKSYLSKE
                     LDRCCKLSNVKRIRVHDLRHSHASLLVNMDVNILTIAERLGHEKVETTWNTYSHLYPN
                     KQLEVAQKLDNLNI"
     gene            complement(36080..36295)
                     /locus_tag="KOU88_002921"
     CDS             complement(36080..36295)
                     /locus_tag="KOU88_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212783.1"
                     /translation="MLKKLRKKKRMTQLELAEKMRRNRSYISKLENQEYKDIGISTIL
                     DLSIALEEDFLELCKYYKLQEIKRRGK"
BASE COUNT        14277 a         4057 c         6322 g        12002 t
ORIGIN      
        1 aaaatatttt atacaatata ttgtaaagga ggtaactttg atgaaagcag aaaaaacaag
       61 tatatatcca attattaaaa ataatttaaa caaaatatca attgttgaat ataaaaaggg
      121 tcaaagattt gtagcatcag ataaagactt acaagaagtg ttctttataa tagagggagt
      181 tgcattagtg gagtgtacta ctagaggagg aaataaattt cttgttgaca ttgtacctga
      241 aaatgagttt ataggcaaaa ttagttacat atatgaacat aatttgaaat gtgatatatt
      301 tgcaaagact aatataaaat tatttcgatt tgaaaaaaat gtatttgaag agttttatct
      361 caaaccagat tttattgcac tatttcacag aaaatgtaca agaagaatat atgaattata
      421 taaaaccaga atggtaagag aactattttc ttgcacagaa gttattgcct attgtatatc
      481 aaataaacaa gaaaataatg tctgcaatat aaaagctatt cgtaatttca gtgaaatcta
      541 ttcaattagt agaaaaagta gataccattc tctgctaaag ttaactgaaa aggagatagt
      601 aaaaaaaatg ggtaatacat atgaaatttt aaactatgat gaattacata aattggcatt
      661 tgaagtaaaa gaatttttgg aagatgagta aaaattgtta cttaatcaaa ataaagtata
      721 ataatttctg taaaaaatag aaatagtctc actgaaaatc aaaaatactt tagttatttt
      781 caatgagact gtttagaaat attgtatact tataatgtat agtataatta ttaatcaatt
      841 tcctttacta tattaatagc ccatttttta gataatgctc taggaacacc aaatataaac
      901 ttaaccactt cttcactata agtgagcaaa acgagtacaa atataggtgc acctttaaat
      961 gcagctataa aagttagagg aatagaagct aaccacatac atcctaattc taaaaataga
     1021 gcatatttag tatctcctcc acttcttaaa ataccaatta taaccaatgt attaaaagat
     1081 ttaagagcca ttagtattcc cattataaag aatatcttag ttatatcaga agctaagcta
     1141 tcagaaacac taaacatttt taataataat ggtatattta aaattaaaat aattccaagt
     1201 attaaaccag ctgaaaatac aagtatagaa aactttttag catattcaat ggctctttta
     1261 atatggtcag ctccaagttc atttccaagc ataatagatg caccagatgc aatacataca
     1321 gctgtcatta tgaagaaatt acctgtactg gttgctatct ggctagctgc tatagcagaa
     1381 gtaccagctc ttgcatatgc aacagaatac aggacagttc caattgccca tacagagtca
     1441 tttacaaata taggaaagct ttttgatgaa aaagatttta taaaaatttt atcaatagct
     1501 tttagatttt ttagaccaaa ctttaatata tagtcttttt tataaaggta aacataagta
     1561 atcattaaaa ttaattcaca tattctagca ataacagtag ctagagcagc accttttaca
     1621 cccaatgcag gaagaccgaa gttaccaaat ataaatccat aatttaaaat aacatttgtt
     1681 acaagtgcaa atgcactaca aatcatacct aacttaggat ttctaacacc tcttgaacca
     1741 gtactaaata cagtacttac agcaattaat ggataactaa atactgcaat actaaagtaa
     1801 tctatacaaa gttttaccac ctcagaatca tacgaaaata tgtgtataat tggctttggt
     1861 gttagtaaag caggaataac aaatacaaaa cttaaaacaa ttgccaatac acaagtaaga
     1921 cctgtgactt ttcttatatt actcacatcc ttctttccat aaaactgtga aataaaaact
     1981 ccagcacctc ctgtgatacc agataaggac atattaaaaa gaaagaaaaa ttggtttgca
     2041 actccaactg aagctacaga tgtttccccc aaactactta tcataattgt atctattaca
     2101 tttacagaag tagaaattaa gttctgtatg ataataggta tacataaaga tagaagtatt
     2161 ttataaaatc ttttattttc gtcttttaaa gaaaatagtt cttgcaaata atcctctcct
     2221 ttttacataa attcttccca ctcatcatat agagaggcaa ggttattttc taaattaatt
     2281 ttttcttggc taacttcttt agctttatct ggattagagt atacttcttc ttgacataaa
     2341 agtatatcta atttttcaat ttcaatctct aacttttcaa tttctttttc tatattttgt
     2401 ctttttattc tatttttctt ttctatttct ctttgttctc tctcttttct tttttcatct
     2461 tttatttgag ttctagtttt ttcttctttt tcttctataa tactcatctc ttggatttgc
     2521 ctttttttat ctatataata atcataattt cccagatatt cagtaattcc attttcatct
     2581 aaaactaaaa ttttatcaac aacagtattt agaaagtatc tatcatgtga tattgtaaat
     2641 atagtcccat cataattagt taatgcctct tcaaggactt ccttagaatc aatatctagg
     2701 tgattagtag gctcatctaa taacaataag tttgcatttg atagtataag tttaagtatg
     2761 gcaactctag ctctttctcc accactcaat gtagaaatct tcttaaaaac ttcttcatct
     2821 acaaataaaa atgcccctaa catatttctc aaagtagttt gagtaagatg agtattattt
     2881 tcccaaatct catcaattat tgtgttatct aaattaagag ttttttgttc ctgatggaag
     2941 taggaaacat gtacattagt tccaaattta atattgccac taagaggttg tagttcatta
     3001 gttattattt taaataatgt agatttgcca acaccatttg cacctataag tgcaactttt
     3061 tcccctctat atatatctaa atccaagtct ttaaaaagta ttctttctcc ataacccata
     3121 gatacatctc taatttgaag aacatcatta ccactctgga cagaaggcgt aaattgtata
     3181 cgagcttttt tcctataagc ttctggttta tctaaaacgt ctaccttgtc taatgctttt
     3241 tctttacttc ttgcacgctt taggtgtttt tctctaccat aagcttttag tctttcaatt
     3301 gattcttctt gcttttttat ttctttttgt tggtcttcaa atttcttaag ctctagttct
     3361 ttttctattt tagataactc aacaaattta gagtagttac cattatatac tttaagtttt
     3421 ttgttgtgaa cttcaaaaat tctatttacg gattggtcta agaaatatct atcatgagat
     3481 attaacatga cagtcccttt atattgtttt aaaaatactt ctaaccattc tattgcttca
     3541 gagtctaagt ggttagtagg ttcatcaagt aacaatagag ttggtttctt aagaagtaat
     3601 tttcctaaaa gaactctagt tttttcacca ccagaaagta tgcttattgg cttatccata
     3661 tcattgtcac taaatcctag tccttttaga actcctttgg cttcagattt atatccatat
     3721 ccatttaaat ctgaaaataa ttctagttta tgtgaatatt catccatgat tttttctata
     3781 attggagagt ttgtttttgt actttcttca gatattttaa cctccaattc tcttaaatag
     3841 gattccattt ctatcaaatt tttaaaaact tctagtactt cttccaaaat agtattatcc
     3901 gaataaaaat tggtattttg ttctaaatat ccgatttcac aatctttaga agtgtaaata
     3961 tctccactat catatccata aattcctgaa attattttaa ataaagtagt ttttccagta
     4021 ccattaacac cgattatacc aattttatcg ccttcattta ctgtaaaact aatattttct
     4081 aatatagaat ctataccaaa acttttattt aagttattac atgacaaaac aatcataaat
     4141 ttctacctcc ttgaactatc taaaattata atgttttgat ataatataat caaggttata
     4201 tgtattagtt ttgaaaaaga aatattttat tgtgaatcaa acaaaaaaga ggacactttt
     4261 aggaggtgaa gatgttggga aataaaaata tatcaatggc agttataaga aggctcccaa
     4321 aatatcatag atatcttgga gacttattag atagggatat acaaagaata tcttctaaag
     4381 aattgagtga tataataggg tttaccgctt ctcaaataag acaagattta aacaactttg
     4441 gtggatttgg acaacaagga tatggttata atgtagaagc tcttcatact gagataggta
     4501 aaattcttgg gttggatcga ccatacaacg cagttcttgt aggagcaggt aacttaggac
     4561 aagctatagc caattatgca ggatttagaa aagctggatt cgagataaaa gctttatttg
     4621 atgcaaatcc tagaatgata ggtttaaaga taagagagtt tgaagtatta gattcagata
     4681 ctttagaaga ctttataaaa aacaataata tagatattgc tgtattatgt atacctaaaa
     4741 atggagcaca agaagttatt aatagagttg taaaagctgg aatcaaaggt gtatggaatt
     4801 ttgcaccttt agatttagaa gttccgaaag gtgttatagt tgaaaatgta aacttaacag
     4861 aaagtttatt taccttatcg tatttaatga aagaaggaaa gtagacaact taaacatatt
     4921 aataatgagc agttgtgaag agtattgaga aagtcagaag atttaatatt aaatcctctg
     4981 gctttttgaa atattaggat aaaaatttaa ataatgtatg gaaataaaca atattaagga
     5041 gagtggtttt tgtggaggaa ttatggaaaa aggcaattaa atttcatggt catgaatgtc
     5101 caggattagc tataggattt aaagcagcac ttgcagcaag agaatattta ggatgtaaac
     5161 agtcaggaga tgaggaaatt gtatgtattt ctgaaaatga tgcttgtgga atagatggta
     5221 tacaagtcgt gctaagttgc acaatgggta aaggaaattt actacttagg atgactggga
     5281 aatcagtata tcatttcttt aatagggaaa atggaaaatc tataagaata tatgtaaagt
     5341 caaagccatt tcaaatggat agagaaggat acaaaaagta cttattagaa agtgattttg
     5401 aagaaatatt tgagattaca gatactaagt taagacttcc tgaaaaagca agaatattta
     5461 aatctcttaa atgtgaagtg tgtggtgaat ttgcatctga gcaatatata aggattgaag
     5521 aaggaaagaa agtatgtctt gattgcttta ataaatatga aagattttat gaggagtatt
     5581 aaaattataa attagattaa agttaaaagt attagatatg tgctaacagt attttaagat
     5641 gaattaggta gcaacataat aaagtatata aataatatta attgaatcat acataattaa
     5701 aaagaggctg attagtattt ataaaataaa atcagtctct ttatgaataa cgaattatta
     5761 ttctggttga ggtgcatcta caggacaagc tcctgcacaa gaaccacagt ctatacaaga
     5821 accagcatct ataacatatg cgtcgtctcc agctgatata cagctaacag ggcattcagc
     5881 ctcacaagca ccacagctta tacaagcgtc agtaatttta tatgccattt tgaaatcctc
     5941 ccttttatat gtattgtaat tcaataacat tataacaaat attattgaat ataacaatta
     6001 aattaattct acaacaaaaa ctttattatg atattcttgt tttaaagttt tacaataaag
     6061 tttaatctgc ttatattttt atttatttta aagaagttta ttttaaaaat aaaattaaat
     6121 ttaaaaagtt atgtattgat tatatttaaa aatgttatac tctaaaaaag tatattttat
     6181 ttaaaaattt attaatacaa aggagattta ctatgaaaaa taaattagtt tacatatgta
     6241 ttatgagtct attgctattt gtagtaggat gttctaataa tccaaataag gaaagtacca
     6301 ttaaaaaaga ctctaagaat aaccaaagcc aagttaaaga agaaaaaaga gaacctgtga
     6361 aaaaagatat aactataagt ttcgctggtg atgtaactat ggggaactat aaaggttcat
     6421 catattatgg cagttttgac catgaattta aaagacaagg agaagattac aattattttc
     6481 ttaaaaatgt aaaacctgta tttgaaaaag atgacttaac agtggttaat ttagaaggtc
     6541 cacttactac agcgtcaaat gcaaaagaaa aaaaatttgc atttaaagga aagcctggat
     6601 atgtaaatat tttaaaatct ggaagtgtag aggcagtaag tattgcaaat aatcattcag
     6661 aagattattt tgaagaagga atgaaagata cacagtttat attggacgag aataaaataa
     6721 attattttgg attagggaaa gatgctgttg tagatgtcaa aggaattaaa gtgggtctat
     6781 tagggtataa tggattatca actgaatata atgaaaaaaa tttaaaacaa atggaagatg
     6841 atattaagtc cttaaaaaag aaatcggatg ttgttgtagt gtactttcat tgggggatag
     6901 aattagatta ttatccagat aaaaaacaaa aagattttgc tcattatgct atagacaagg
     6961 gagcagattt agttatgggg tctcacccac atgtgattca aggaatagaa aagtataaaa
     7021 ataagtatat agcttatagt ctagggaatt tttgctttgg aggaaataag aatccttctg
     7081 atacagatag ttatatatat caacaaacct ttactttttc agataataaa ttaacttcaa
     7141 ttaaagagcc aaatataata ccaacttcaa taacatctag taactccaga aataattatc
     7201 aaccaaaaat attggatgga agtgagaagg atagagtttt aaataaactt gaaaaaataa
     7261 gcaaagattt aaataaataa aatgtaaaaa aaaataaata tatatattta ttttaataat
     7321 ttatattttg tttagggtat ggtaaatcgt ggtattaaat aagtagattt taatagttaa
     7381 attatagtca attataataa agctatttaa tctacttttt taatataaaa atataagggg
     7441 gaatttgtaa tggcttgtaa cacttgtaaa atgtgcgaaa gtgcagacaa gaaattagaa
     7501 agttttgtag cttcaaagga tgttgaaaca gcatttcata gaacagaaga tcagaaagtt
     7561 aagtgtggtt ttggacttca gggggtttgt tgtagactct gttcaaatgg accatgtaga
     7621 gtaactccta aatcaccaag aggtatatgt ggagcagatg cagacactat agtagcaaga
     7681 aactttttaa gagcagtagc atcaggagca gcttgttatt tacatgtggt agaaaataca
     7741 gctaagaatt taaaaaatgt tggaataact aaaggtgttg ttaaaggaga aaaaacatta
     7801 aatcaattag cagagatgtt tggaatagaa agtgatgaaa agtatgataa atgtataaag
     7861 gttgcagaca aagttatcaa cgatttgtat aaatcaagag atgataaaat ggaattagta
     7921 gaaaaaatag cttatgcacc tagagtgaaa aagtggaaag agttaggtat aatgcctggt
     7981 ggtgcaaagt cagaagtttt tgatgcaata gtaaaatcat caacaaattt aaatagtgac
     8041 ccagtagaca tgctagttaa ttgtttgaac ttaggtatat caacaggatt atatggtctt
     8101 acactaacta atcttttaaa tgatgttatg ttgggagaac cagttataag aatggctcct
     8161 gtaggattta atgtaataga cccagactac ataaatataa tgataacagg ccatcaacat
     8221 tcaacatttg caaatttcca agatagatta aaagatgaag atgttataaa attagctcaa
     8281 tctgttggtg caaaaggctt taagctagta ggatgtacat gtgttggtca agatttacaa
     8341 ttaagaggag aacattatca agaagtattt gctggacatg caggtaacaa ttttacaagt
     8401 gaggctgttt tatcaactgg agcaatagat atagttcttt cagaatttaa ctgtactata
     8461 ccagggcttg aaccaatagc agataaatat aaagtaaaaa tggtttgttt agatgatgtt
     8521 gctaaaaaag cgaatgcaga atacataggt ttagacagaa gtaaattaga tgaacttagt
     8581 aacactttaa tagaaaaagc attggagtct tataaggaga gaagaggaag tattgaaata
     8641 gatataccaa aagaccatgg atttgaacaa tctttaactg gtgtaagtga aaagaacctg
     8701 aaagcgtttt taggagattc atggaaacct cttattaatt taattgcaga aggaaaaatt
     8761 aaaggtgttg cagctgttgt aggatgttca aatatgacag caggaggaca tgatgtaaat
     8821 actgttgaac ttactaaaga attgattaaa aaagatataa tagtactatc tgcaggatgt
     8881 tctactggag gattagaaaa tgttggtctt atgtcacctg gagcagaaga attagcagga
     8941 gaaaacttaa aagaagtatg taagacttta ggaataccac cagtattaaa ctttggacca
     9001 tgtctagcta taggaagact agaaatagta gcaacagaat tagcagctga acttggaatt
     9061 gacctaccac aattaccatt agtgctttca gctccacaat ggttggaaga acaagcatta
     9121 gctgatggag cgtttggtct tgcccttggc ttacctcttc atttagcttt acctccattt
     9181 ataacaggag gaaaattggt gacagaagta ttaacagaaa aattaaaaga cttaacagga
     9241 ggacatgtta tagtgaatcc agaccctaaa tcttcagcta atcaattaga agaaataata
     9301 atagatagaa gaaaaaattt agggttaaag gatgtggaat gcaatgcata gaatttttat
     9361 aaataaagat ttatgtacag gatgtaagag ctgtgtacta gcatgtatgc taaaacacaa
     9421 taaagattat gacatgtaca ctcttgattt agaaaatata gataatgata gtagagggca
     9481 tatagaatta gatagtagac ataataatcc agttccaatt ctttgtagac actgtgatga
     9541 acctgaatgt gtattagcat gtatgagtgg tgcaatgcat aaagatagtg aaagtggaat
     9601 cgtttcatat gatgaagaga aatgtggttc atgttatatg tgtgtaatgt cttgtccata
     9661 tggattatta aagccagatg atagaagcaa gcagaacata cttaaatgtg atttatgtaa
     9721 agatgaggag tatcctagat gtgtagctaa ttgcccaagt ggagcaattg aattacagaa
     9781 ggaggaaaat gatgaattat gtagtgttag gggctagtgc agctggtata aatgcagtaa
     9841 aaacattaag agaattagat aaagattcaa atatagtagt aatttctaaa gatgaaaacg
     9901 tatattcaag atgtatgttg catcacgtta tatctgaaca cagaacttta aaacaaataa
     9961 attttgttga tgaagatttt atggagcaaa ataatgtaaa atggattgca ggtaagactg
    10021 ttaaaggtat agacataaat aaaaaggtag ttcagacaga agacattact gtaaattatg
    10081 ataaactttt aatagctaca ggtgcatctt ctgctattcc tcctataaaa aatttaagag
    10141 atggaaattt tgtatattct gtgagaaaca tagatgatat ttataaaata aaagaaaaag
    10201 cacaaaattc taaaaatgta gttataatag gtgctggttt agttggtata gatgcattag
    10261 tgggattatt taaatatgag cagttaaata tttctgtagc ttttatggaa aagtacattt
    10321 tagatagaca attggatgaa tatacagcat cagtgtatga aaataagttc aaagaaaaag
    10381 gtgtaaaatt ttacccaagt gcatcaatac aagaaattgt attggataac agtaaaaatg
    10441 ttacaggtgt tgcattttca aatggtgaag ttttagatgc agacatggta attgtagcta
    10501 caggggttaa accaaatgct gactttttag atggaacagg aatagaatat gatagaggta
    10561 taataataga tgatatgtgc caaacaacac aaaaagacat atatgcagca ggagatgttg
    10621 taggtaaaaa tgctatttgg cctctggcag taaagcaagg aattgtagct gcctataata
    10681 tggttggaaa agataagaag atagaagatg aatttgcttt taaaaacagt atgaatttca
    10741 tggatatacc aactatttct ataggaatga atacacctgt agatgatagc tataaagtat
    10801 taaccagaca tggaattaat gattataaaa agtttgtttt taaagataat gtaatctatg
    10861 gagcagttat acaaggagat atttcatatg taggtgtatt aacttattta ataaaaaata
    10921 aagttgaaat atatgattta gaaaatagga tatttgatgt atgttatgca gactttttta
    10981 atataaaaga aaatggagaa ttttgttata gtgtatagta tatacgtgaa gtaaggttta
    11041 taaatacagt aaatcaataa atagagttat tctaaaataa gaaaaatgac aaatcttatt
    11101 tagaaatagc tctatttttt gcaattaaat ttaaattata ttcaatttgt aaaatattat
    11161 tttgaacaat tatacatata ctctctagtt agaggtaaat cattttttat acctttagtg
    11221 aaaagtattt gatgtatatc tataatacca gtgttgaaag cagcagcaca agaacaaagg
    11281 tataaatccc acattcttat aaacttatca tcaaacattt ctttaatctt tggaagattc
    11341 tcagagaaat ttttttgcca gtatagtaag gtttttacat aatgtaatct tagactttct
    11401 acgtctatag tatgatattt gtaatcacta caaatatgta tcatttctct taggctagga
    11461 ataactcctc ctgggaaaat atattttttt atccaagggt ctccataaga ttcctgcaat
    11521 ccacttatat agtgaagtaa aaacaatcca ccatctttta aaacagcatt tacgttttta
    11581 atgaaaagtt catagttttc tctaccaaca tgttcaagca tcccaacgct tacaactcta
    11641 tcaaacataa ggtctgattt ttttaattct ctatagtcca taagtcttac ctcaagatag
    11701 tcttgaaggt tctcttcttt aattcttgtg ttaaattcct taaattgctc ttcgctaagt
    11761 gtaattccaa cgccgtgaat tttatatttt tttgcagctt ctattagtaa aaatccccaa
    11821 ccacaaccaa tatcgagaag gctcatacct tcctctaaat ttagtttagt taatatgtgg
    11881 tgaactttat tgacttgagc atcataaaga gtatcattat catttctaaa gtatgcacaa
    11941 gaataactaa gtgtcttatc taaccataag ctataaaaat cgttgccaat gtcatagtgg
    12001 gcatgtattt ctttcttttg atgtctcatt gaatttgatg agtgcaatag atgttttaca
    12061 gctgaattat caatattgaa tttgtctatt tgttttaaaa gtagatttaa agttaagaat
    12121 aaatctccct caacttcaat gtctctattt atgtaggctt ctccaagtgc taaagatgta
    12181 ctttttaata gttcagactt gctaatatca ttatttacta taactttgaa ctgaggggag
    12241 ccctctccaa ttagaaattc ttcctcatct ttaagcctaa ctagaaatgg tgtttcacca
    12301 aatctctcta aatagtcttt taaaaaattt tttgtaatat tcatattacc agctccttct
    12361 aatgtaaatc cagtaagttt ccctgcttaa aatatattat agtccttttt ttaaaaaagt
    12421 aaaatttttt caataaattt tttatttaaa ggaaatttat tttttataaa gaaatttcat
    12481 gttgtagtat attttttgct tataaatttt ggtactggat ataatattaa actgttaatg
    12541 atataataaa tttaatctat aaagtaaata aaattttgta ataaatagtt aaagctattt
    12601 tataaggaga tatatgatgg aagtatatgc tttggttggg tcaagtggca cagggaagag
    12661 ctttaaggct ttagagttcg catatgaaaa tgatatagaa tatataatcg atgatgggat
    12721 tttaatatac aaaaacaagg ttttagctgg gatatcggca aaacaagcaa atactactat
    12781 agaagcagtt aaaagggcta ttttttataa tttggagcat agacaagaag ttagagaagc
    12841 aattaaaaaa gaaaatataa gaaaaattct tattattggg acatcaaaaa aaatggttaa
    12901 tcaaattgta gagagattgt caattggaag ggtttgcaag tttataaata tacaagatat
    12961 aagtactaaa tatgaaatag aaatagcaaa acaagctaga aaagaaggaa atcatgtaat
    13021 tcctgttcca gcagttgaga taaaaagtat ggcaagtggt cttagtataa attctttgaa
    13081 gcgacttttt agaaaaggaa ataatatgaa tatggtagtt ttagaaaaaa caattataag
    13141 accaactttt agttatatag gaaagtttta tattagtgct gatgtaatta aacagattat
    13201 tgaatatgaa gtatacaact ttggaagcat tgatagaata aataaaatca atatagagaa
    13261 ttgcaataat tttatgaata tttttgtaag tataaatatc aatgatttag aaactataaa
    13321 aaaaattgaa gacatacaac agacaataaa aaagtctatt gagaaaatga ctttagttaa
    13381 tgtacaaaaa atagatatta acattcataa aattaaaaaa ataaacttcc tccaatgtta
    13441 aaaaataaac tgagaaaatg atatactaat ttgcaataaa gtgtgctata attaaactgt
    13501 aaatttagga aatggttttt tctaaatgga gtatacataa ttataacgta tttataaggg
    13561 ggctttcaaa tgtcaggaaa agatgtaaat gtcttcgaga tggcgcaatc tcaagtaaaa
    13621 aatgcatgtg ataaattagg tatggaacca gcagtttatg aattattaaa agaacctatg
    13681 agagttatag aggtttcaat tccagtaaaa atggatgatg gttctataaa aacttttaaa
    13741 ggatttagat cacaacataa tgatgcagta gggccaacaa aaggtggaat aagattccat
    13801 caaaatgttt caagagacga agtaaaagct ttatctatat ggatgacttt caagtgttct
    13861 gtaacaggta taccatatgg tggaggtaaa ggtggaataa tagtagatcc atcaacttta
    13921 tctcaaggtg aattagaaag attaagtaga ggatacatag atggaatata taaattaata
    13981 ggtgagaaag ttgacgttcc tgcaccagac gtaaatacta atggtcaaat aatgtcttgg
    14041 atggttgatg agtacaataa attaactgga caaagttcta taggtgttat aactggtaag
    14101 ccagttgaat ttggtggttc tttaggaaga acagctgcta ctggatttgg tgttgctgtt
    14161 actgcaagag aagctgctgc taaattagga atagatatga aaaaagctaa aatagctgtt
    14221 caaggtatag gaaacgttgg ttcttataca gttcttaact gtgaaaaact tggtggtact
    14281 gttgtagcta tggctgaatg gtgtaaatca gaaggttctt atgctatata caatgaaaat
    14341 ggtttagatg gtcaagctat gttagattat atgaaagaac atggtaactt attaaacttc
    14401 ccaggagcta agagaatatc tttagaagag ttctgggctt cagatgttga tatagtaata
    14461 ccagctgcat tagaaaactc tataactaaa gaagttgctg aatctataaa agctaaatta
    14521 gtttgtgagg ctgctaatgg accaactact ccagaggctg atgaagtatt tgctgaaaga
    14581 ggaatagttc ttactccaga tatattaact aatgctggtg gagttacagt ttcttacttc
    14641 gagtgggtac aaaacttata tggatactac tggtcagaag aagaagtaga gcaaaaagaa
    14701 gaaatagcta tggttaaagc atttgaatct atttggaaaa tcaaagaaga gtacaatgtt
    14761 acaatgagag aagctgctta catgcattca attaagaaag ttgctgaagc tatgaaatta
    14821 agaggatggt actaagattt actcttaata aataatagga tataattatt taagatataa
    14881 aggggctgta catagtacag cccttaaatt atgtggcttg caatgaagta agctattttt
    14941 gttttaactt ataaataact tgataaatta tgtaatttag aatgtatttt ttaccaccac
    15001 atgattacaa attagaagag ttagattaga tttttagaca tgaacttatg cattttaaaa
    15061 gcaaagacct taatttaaag tatctagtat tatttttaaa aatagtatat tggtttaatc
    15121 catttatata tataatggaa aaatatatgg atttggattg tgaactttat tgtgatgaga
    15181 gagttttaaa aaattgtact gtacaacaaa agcaagaata tgctctaact attgtaaatt
    15241 caatgaaaag aggtacaaat ttttcaaata aatttgtagc tggattaaat aaacaatctg
    15301 atattagaaa aagagtaata aacatgttca gtgaaaaaca taaaaatggt atcttaatgg
    15361 ctttgattat aagcttgttt tcttctatta cattttttaa attcgattca actagtatta
    15421 ttgaagagaa tgatttctta gagaggttaa gatatacgtt tgaaggaagg caagaagata
    15481 tgtttgtaac aatagatttt acatatgcag atgcacctat aaaacttaga aaagagcatg
    15541 aagaaaactg tagagtcaat ggaatagtac caaaagattc agattcaata gaaattattc
    15601 ctagatttta taaagattgt atggatttaa aaaaataagt tagacttaat attgatgttg
    15661 atattatgaa ttttttatat ttaagcaatt gaaaatttta ttatagattc aattttatat
    15721 gtgtttaagt atgaaattta tagatagttg aaataattaa atatgattga tgcataggaa
    15781 tcattactaa gctataatta attatagggg agtttaaata aattatgagt tacacaatta
    15841 taaaatgata aaaatagtta tctgttacaa aaaatgtatc tttttaatta ataaagataa
    15901 tatgaaaact taaaaggcaa ataaacttaa atataaaata ctcttaaata agataggaga
    15961 aaaatgtatg tctaacttta ttctaaatgg gatttttaga acagttatag taagtagtct
    16021 aagcattctt ctgatattga ttttcaagaa aaatgtattt aaaagattta gcaaaaaatt
    16081 taattattat atatggatga tagttgttat taaattattt ttaccattta catattatac
    16141 ttttacaata aatatcttga gaagtaaaaa acacattaat attaataaca taaatttaga
    16201 gggatttaat aatgtttcaa ctataagtaa taatattata ttgtacactt ggattataac
    16261 tgtagtagtg tatttaattt acactatatt taaatatata aaacttaaaa atttaataaa
    16321 tgacttatct tatgatgttg atgatagaga gattgtaaat ctttataaaa atatattaga
    16381 agaatttaat ataacaaaag atataaaact caaatactct tatgaagttg aaacaccagc
    16441 attttttaat tcatgtgtac ttttgccacc acatgagtat aaattgaaag agttagactg
    16501 gatttttaga catgagctta tgcattttaa gagtagggac ctttatttaa aatatgtaat
    16561 cctgttttta aaaacagtat attggtttaa tccatttata tatataatgg ataaacatat
    16621 agatttagat tgtgaacttt attgtgatga aagagtttta aaaaatcgaa attcagagga
    16681 aaaaaaggat tatgctttaa caattctaaa tgcaatgaga aaaggttcaa atacttcaaa
    16741 taaatttata gctggactcc ataagcaatc tgatattaaa aagagagtta tgaatatgtt
    16801 taatgaaaag tacaagaatg gtatattaat ggcattaact ttatgtttat tatcttctat
    16861 tacttttttg aaggttaatt caacgagtat tgttaatctt aatatattgc caaaaggaat
    16921 ggaagaaaaa gatgttacta atagtgcaat tgttacaatg atagaattta catatgcaga
    16981 agctcctaaa agtatgagag aagaacataa aataaattgt gaattcttag gtttaatacc
    17041 taaagactct gataaaatag gtgttggtat agaatattat gacagtctat tgaatgatta
    17101 aataaatatt attttaacag atattaatta taaagttttg aatagtaatt tgttgagaaa
    17161 taaatatatc cttataaaaa tagatactta tataccaaga ataaaaaata gttaagatag
    17221 tacacaagga tatacttata aagaacttaa ataagtgaaa taaattatta attataaggt
    17281 ttataatttt aaaaaattag ataaattcag gtgtaaaata ctataaaaca caattcggaa
    17341 aagtgtatgt tgaacttcat ttaaaatgga atttcaaagt tgctatagta agtagtttaa
    17401 gcattcttct tatattaatc tttgagaata atgtatttaa aaaagttagt aaaaaattta
    17461 actattgtat attaatgata gttgctattg atatattatc taaaaaaatt aagtatgaaa
    17521 agattactgt taggacaatc ttttcatact taatttttaa tatttatatt atccaaaatt
    17581 ttcatctttt taacttagaa tttgagaatc actattagga aataggcttt gatttatgta
    17641 gggttaaaaa tttcacagaa tatctaactt tatactaaat ccatcaaaaa atatacgcca
    17701 tataaaagcg cataaaaaaa cacataaaac aatatttatg cgcactttaa cctcgaatgg
    17761 tacaaaattc tttactttta cagacccata ttatataatt aagtaaataa tgtatattta
    17821 ggtgacatat tggataagct aatttattta ttttattaat ataataatac tataaaagtt
    17881 atataaagtg gtttacaaaa aagttacaga tagagctttt attaatgtat tgtgtattag
    17941 tattttatcc ttaggtacac ttcacctaca aaatagaatc ataagataat tatgggaaaa
    18001 ttttaggagg tttatcgtga agaaaaagat attaatacca gtatttgcat cagttatggc
    18061 attatcagta agttcaattg taaatgcaga tgaagtaaat gattcatctc aaaataagga
    18121 tgataaaaca aatactgaat taaatttagg tgaatataaa gaagtaaaat ataaagttgc
    18181 aaaaataaaa gatggagtag ctataaagat aagagaagaa ggtcaagttc aaaacatagc
    18241 ttattctgga gatgaattta cggttttagg aactcaagga gaatgggtta aggttaaagt
    18301 tgaagatggc gaaggttggt tagctactag atatgtagat atatctgaag gtgtaggata
    18361 tactaacgct gataaagtaa acttaagaaa agataagagt gaaagttcag aagtaattga
    18421 agagctggaa aaaggaagtt ctttattggt tttggaagat aatggagatt ggttaaaagt
    18481 taaagatggg gaaacagaag gatatgtaaa atcatcttat atatctgata aagctcctgt
    18541 aatagaagag ccacaagtaa acccaagtgt taatcaaaat ggagattcta caaataataa
    18601 taatcaacaa aacaatgcaa ataatattca acaagataat acaaatgaca atcaacaaaa
    18661 caataattca aatgtgccaa cagctaactc taatgcagtt caagctgtac ttaacttggc
    18721 atattctaag caaggttgtc catatgtttg gggagcagaa ggaccaaaca cttttgactg
    18781 ttctggattt acacaatatg tgtatagaaa tgcagtagga aagaatatac caagaacatc
    18841 taaagcacaa tctaaatatg gacaaactgt aagtaaagca aatttacaac caggagactt
    18901 agtattcttc acaactaatg gttctggttc tgttagtcat gttggaatat atgtaggtgg
    18961 gggtaatatg atacattcac catcaacagg aaaaacagtt agtgtaacta gtataaattc
    19021 atcatactat acagcaagat ttgttacagc aaaaagaata ttataatcgg tttgtaatat
    19081 gacaaattga taaatacata aatatatata aacgctctat attatattta atttaatcat
    19141 ggaaacaaaa aatgattata ttttaaatgt actatagagc gtttttgtat cactttaaat
    19201 ctaatcaaga ttcaagttaa tatgactgtt aaataggagc cttttcatat gatgattatt
    19261 tgcgcaatcc cttgacagga tagggcaaag gtggtaagct actaacagta caaaaatact
    19321 tttaatttta gttcagagag gctaaaaaag gaggacgaaa gatgttaaaa tcaagaaatt
    19381 taatccaacc agaagacttt tcaatagaag aaatagatga aatattagaa ttagctcaaa
    19441 aaataattga caatccgtca aaatattctc gtatatgtga aggaaaacta ttagctacat
    19501 tattttatga accatcaaca agaacaagat taagctttga atctgctatg aacagattag
    19561 gaggacgtgt agtaggcttt tcagagccaa attcatcctc tgcatcaaaa ggtgaaactc
    19621 taggagatac aatgaggata gtatctggtt atgttgatat aatagctatg agacatcctc
    19681 aatcaggtgc agcttcagaa gcagctagat atacggaagt gccatttata aatgcaggag
    19741 acggcaagaa ccagcatcca actcaaacac ttacagactt acttactata aaatcattaa
    19801 aaggaacttt agaaagccat acaataggat tatgtggtga tttaaaatat ggaagaactg
    19861 tgcattcttt ggttaaggct atggcaagat ataaaaatac aaagtttgta tttatagcgc
    19921 ctgaagagtt aaaaatgcca gattatataa aagaagctat aaagggacat gcatattatg
    19981 aaactaataa tttggatgat gttataggaa gcttggatgt tttatatatg actagagttc
    20041 aacaagaaag atttgaagat aaatcagagt atgaaagact taaaaactat tatattttaa
    20101 ataaagctaa attagaaaag gcatctaaag atatgttagt aatgcatcca ttaccaagag
    20161 taaatgaaat agacatagat gtagatagtg atgatagagc tgtatatttt aaacaagcta
    20221 aatatggaat gtatgttaga atggctttaa taataaaact tttaggtata aatgaagact
    20281 aatagttatc atataatagt aaaacaaagg agattttggg atgtataaaa ttctggaaaa
    20341 tatatatata ggcgaagata tgtatagaat gaaagtaaaa ggtaattttg aaggtaaaat
    20401 gggacaattc tatatgttaa gagcatggga tacttatcca gtactttcaa gacctataag
    20461 tatacatgat atagatgaag aagggataac ttttctttat aaagtagtag gagaaggaac
    20521 tcaaattttg agtaacctaa aggtaaatga tactataaaa ttggaaggcc cttatggtaa
    20581 tggatatgct aaggttgatg gaaaggtagc tctagtagga ggaggaatcg gtgtagctcc
    20641 actatatttg gttgctaaaa atataaaaaa ttgtgatgca tatcttgggt ttagagaaga
    20701 tgttatatta gaagatgaat ataaacaagt atgtaataaa gtctatacaa cagtaggaaa
    20761 tacttttgta acagatataa ttgatgttga gaaatatgat tatatattaa catgtggtcc
    20821 aactccaatg atggaaaaat tagttaagat ggtagaaggt actaaaacga gaattatggt
    20881 atctcttgaa aaccatatgg cttgtggagt aggtgcctgt ttagtatgta cgtgtaaaac
    20941 taatggagga aataaaaaga cttgtaaaga tggtccagtg ttctggggag aggacgtgat
    21001 ttttaatggg taatttaagt gtgaaatttg gaagtgtaga atttaaaaat ccagtaataa
    21061 tggcgtctgg aacttttgga tttggaaaag aatataatga gatttatgat atacaaaaac
    21121 ttggtggtat aagtagcaag ggtcttactt taaataaaaa acctggtaac aatggtatga
    21181 gagttcatga gacaccatcc ggtatgatga atagtgttgg gcttgaaaac ccgggagttc
    21241 aaggatttat agactatgaa ttaccttttt ttagtaaact agacttagtc agaatagcta
    21301 atgttggagg tgggacatta gaagactact tattaggggt tcaaatgtta aatgacaagc
    21361 ctatagacat tattgaatta aatatatctt gcccaaatgt caaagctggt ggaatggctt
    21421 ttggtataaa aaatgaagtg gcaagagaag ttgttcgtga ggtaagaaac ataacgaaac
    21481 tgcctttagt aataaaatta tcacccaatg cagaagatat tgtaggaatg gcaaaagttt
    21541 gtgaagaaga aggtgctgat ggagtttcat tagttaatac ttttaaagca atggcaattg
    21601 atataaaaag tagaagacca gtatttgaaa atgtatatgc tgggttatct ggaccagcta
    21661 taaaacctat agctttgaga atggtacatg aagtgtgtaa aaatgtaaat atacctgtaa
    21721 tgggaatggg cggaataact aaagccacag atgctataga gtttataatg gcaggagcta
    21781 cttgtatcca agttggaact gcaaatttta tgaatcctag aataggtatt gaaataatag
    21841 atggaattaa tgaatttatg gatagagaag gaataaaaag tttagacgaa ataagaggaa
    21901 ttatataagg tagaataaat agtattttaa agataaaaaa tatagattaa ataaacaata
    21961 attttataac attaacatgg aggaaaaata atatgagtaa agtagatgta gtggatatat
    22021 taaagaaaag tgatgcattg ttggagggac attttttatt atcttcagga aaacacagta
    22081 atagatacgt acaatgtgca aaagtattaa gatttccaga atatgctgct gaggtattaa
    22141 gtacagttgt tgaacaaata aaagacttag atatagactt agtagtagga ccagctatgg
    22201 gtggagtaat agtttcttat gagttaggaa gacaattagg aaaagaagct gtatttactg
    22261 agagaaaaga caatacaatg gagttaagaa gaggatttga agttaaaaaa ggagcaaaga
    22321 taataattgc tgaagacgtt gtaactactg gtaaatcaac tatggagaca aaaagagtat
    22381 tagaagcctt aggtggagaa gttgtaggtg ttgcatgtat agcagataga actaatcatg
    22441 atataggtat gcctatatat agtgctataa aacttgatat tcaagtttat gaatctgatg
    22501 agtgtccttt atgtaaggaa ggaaaattac cagttgttaa gcctggaagt agggagttca
    22561 aggaattagg gatgtaataa aaacttaatt atttatagtg ttacttaaaa aatgtaaatt
    22621 ttttagagta aaaatttgta atataacata taacttaaaa ataaaaagca gttagcctta
    22681 taaatgaagg ttagctgttt tttttgttaa aaatatattt acaaaataag agatagtagc
    22741 agtacaatat aagtataagg taaaagtatt atatattagg gaggggtaag tatgaaaaat
    22801 caattaaatg aaaatcataa aaaggttgta ttttttggag taggtgctgt aggagctact
    22861 tttgcagaac aattttttaa ctctaaatat gattttaaaa ttctttgtga taatgaaaga
    22921 aagaaaagat atttagaaga aggatttata ataaatggaa aaaggtatga ttttgattat
    22981 gtaactaaag atgagtataa acaagaggct gattttataa ttataggtct aaaatataat
    23041 aatttaaaag aaaatataaa agaattagat ggattagttg gaaaaaatac agttataatg
    23101 tctctgctaa atggagttga tagcgaagag ataataggag aaagatttgg aattgaaaaa
    23161 atggtatatt catatgttac caatatagat gcaaagaaaa tcaataataa tattatacac
    23221 actactaatg ggataattgt atttggtaac aaagataata gtgaagatag aaaaactaat
    23281 ataataacca aagtctttga tgatgtaaat atagaatata ctttatcaaa agatattcaa
    23341 cgagatatgt ggtggaagta catggttaat attggtgtaa atcaaacttc agctatactt
    23401 ggtgcacctt atggagtttt tcagagttct gagcatttaa gagaattagc aaaatctgca
    23461 atgagggaag ttgttgctat agcacaagca aaagacatat ctcttacaga agatgatgtg
    23521 gaacattcat tacatagaat actagaacat tcaaaagaag gaagaacatc aatgcttcaa
    23581 gatgtggaag ctcatagact tacagaagta gatatgtttt ctaagaatat ctgcaaactt
    23641 ggaaaaaaat ataacatacc tactcctata aatcagactt tcttttatat gataaaagta
    23701 attgaaagta gattttaaag ggtctttgta agaaatattg ataattattg attttaaatt
    23761 ttattaatgt tatatactat ttaagttact aaatattttt aactcttcaa tgaaaatagt
    23821 tgctgctttt gataaagtta tatcttttgg aaatatatat gagaaatgtc tgttgtagct
    23881 gcttccaagc tctatgacag acagctcatt gtttagaaca ggtaagcttg tcactagatt
    23941 agagactatt gtaattccta aattatttct aacagattct ttgacagcat aattacttcc
    24001 aaaaaccatc atactttttg gaataatttc tttaacactt aaaaacatat ctaaataatc
    24061 tctggttcca gaaccatcct ccctgactat ccatttttgg ttttgaagtt tatcaaaact
    24121 aaaatctttt aataaatgac tcttgtatgg aagtgctaaa accatcttat cttcaaaaaa
    24181 atattcttga ataaatgaag gggaagagca agtgccttca ataagaccaa tgtctaaaat
    24241 ataatcctta acatgagaag atacgattga tgtatttttt ataaaaactt ctacatctat
    24301 gtcaggatac tttttagaaa ataatgctag aaaatttggt aaaatatact ctccaatagt
    24361 taaacttgca ccaatcttta agtgaccagt tatagcatct gaaacttggc ttacatcatg
    24421 ataagtaata tttaaaagat ttaatatttc tttagctctt ttgtacaaga tttgtccact
    24481 ttctgttata aaaatggttt tttgtttaat agacctgttt ataagcacaa ctttaaaata
    24541 attttctaga ttttttatgt gtttacttac acttggttgt gatagattta aatattcccc
    24601 agctttagta aagtttttgt attcaacaac agctacaaat gtttttaatt cttcaaacaa
    24661 ttttttgtct cctttaccta atgaaatttt acatttttta tatactttct acagataatt
    24721 atactatata taataaccat taaaaacatt aatcattacg atattatata tttattttac
    24781 ttatggttat tacaattata tactattgct atgaagaaaa ctatattaat tataaggtag
    24841 gtatattatg ttaaagaaaa aaagcagttt gacattaaaa actataaggg aaatattacc
    24901 aggactgttt gtatcagtat tagtaggtta tattagtata tttatttcta ttttaattcc
    24961 taaggtaggg gcagcatcaa tttctatatt tttaggtatg tttgtaggaa acctattttt
    25021 aaatcaaaag gtatttcaaa aaggttataa attttcagag acagatttgt tatcatattc
    25081 aatagtacta ttaggagcaa cactcagtgt atctacctta atagacttaa aagtttcagg
    25141 aattttattt ataatattgc aaatgacaat aacaataata gctgcacttt atataggtaa
    25201 aaaactagga tttgaagaaa actttagatt tctaatggca agtggaaatg cagtatgtgg
    25261 ttcttctgca ataggagcaa cagttccagt ggttaatgcg acagataaag aaaagggaat
    25321 tgcagtaact attgtaaatg ttactggtat atttcttatg tttttacttc caataatatc
    25381 tcaattttta tatagccatg aacttgtaaa aacttcagca atgataggtg gaactttgca
    25441 atcaattggt caggttgtag caagtggagc aattgttgga gaaaatgtaa aagatttagc
    25501 tactattttt aagatagtaa gagtaatatt tctagttgtt gttgtattag tatttggaca
    25561 tatgaaaaat caatctaata gggaaattct tgaagaagaa aaggatgaga taaaaaagaa
    25621 aaaagtgact ataccatggt atgtaattgg attctttata acttgtgcac ttttttcaat
    25681 gaacattata ccacaagaag tatctgtgtt gtgcaaagaa ataagtaaca aactagaaat
    25741 aatagcttta gcagcaattg gattaaaggt taatgtaaaa gatttagtga aacaagggaa
    25801 agaagtttct ttatatggtt tatttgtagg tacagtacaa gttgtatcag ctgtagtttt
    25861 aataaaaata tttatatagc ataaaaatag tatttgtaat attaatttga ttaactaaaa
    25921 taatatgata ctaataattt ataatataaa taaaaaatga atttcgataa gtttaagtgg
    25981 gtataaactt atagaaattc attttttatt taaggtaaaa atttaaagta aaatattatt
    26041 ttacataata ataaccttat aaattttgaa attacttatc tttgtgttaa aataagtaaa
    26101 atgcacatat tagagctaag tttttaagta aataaacaaa atgaaaatat aaatattaag
    26161 gagatttggt atatgaatgt ttatgaaaaa ggtaatggag ttatactaga aggagtaaca
    26221 gattttgacc cagtacatat atttgagtgt ggtcaatgtt ttagatggca caaacaagaa
    26281 gatggctcat acactggagt tgcaaagggg agaatattaa atgtcaaaaa agagaatgat
    26341 aaaatatatt taaataatac taatttaaag gagtttaaca gcatttggta taattacttt
    26401 gatttaggaa ctgattatgc agaaataaag aataagctaa aaaatatgga tgaatattta
    26461 aataaggcta ctgaatttgg atggggaata agaatattaa gacaagatgg atgggaaatg
    26521 cttatatcat ttataatttc ctctaataat aggattccta tgatacaaag agcgatagaa
    26581 aatttatcaa gaaagtttgg taagtatata ggtgaatatg aaggcaatga atactatgca
    26641 ttcccaacac cagaagaact aaataaggcc tcacaagagg aaataagagc atgtcaaaca
    26701 ggttttagag ataagtacat aaaaagtact acacaggcag ttatagagaa taatgatgag
    26761 gtatctgaat atacaaattt aagtacagag gattgtagaa aagagctttt aaaatttaat
    26821 ggagtaggac caaaagtatg tgattgtatt gcattatttg gtatgcaaaa atatgattct
    26881 tttccagttg atgtttgggt taagagagtt atgcaagaat tttatataga tgaagacatg
    26941 agtttaccta aaatgagaac ttatggaatc gataaattta aagaaatgtc tggatttgct
    27001 caacagtact tattttacta tgcaagagaa ctcggtatag gaaaataaat taagggggag
    27061 aaattatggg agtaatagga acaatatttc tgttctattt aattatatca tatctagctg
    27121 gagccataat ttctgtgatt atattacttg aaaatagaga ccctgcaaaa acaatgtctt
    27181 ggctattgat gtttattata tttccaggtg taggtttaat gatatatgct atttcaggta
    27241 gaaatattag gaaaagaaaa ttatttaaga ctcaaaaact agctaataat ataaaagaaa
    27301 agaaactatt tgatacatta gaaaagataa cagaaatagt tgaattagaa aaagaatcta
    27361 taaaacaaaa taagctttta agagatgaag aggatggtag ttatagaaaa agggtaataa
    27421 atatgttgtt aaagactggt atgtttccct ttactaaaaa taataaagtg gatgtatttg
    27481 tagatggaaa tgaaaagttt aaaagactta tagaagatat aagagaagct aaagaccata
    27541 ttcatttaga gtactttatc atcaaagata gtgaaatagg tagggtgtta aaagaagaac
    27601 ttataaaaaa ggctaaagaa ggcattaaga taagaatttt atatgatgat gtaggatgct
    27661 ggagattttg gtttaataga aaatttttcc gagaaatgag ggaagtaggt atagaaattg
    27721 cagcattttt acctacaaaa tttcctataa taggagggaa attaaactat agaaatcaca
    27781 gaaaaattgt tgttattgat ggaataattg gatatacagg tggaataaat ataggagatg
    27841 aatatttagg caaaaatgat aagtttggat attggagaga tactcatatt aggattaagg
    27901 gtatttctgt atacatgctt caaatgacat ttctgattga ttggtattat acgacaaaag
    27961 aagtattagt gactaaaaat tatttcccaa gtgtagggaa tgttggtgaa agtatgatac
    28021 aagttgttgc gagtggtcca gacagtgact gggaagatat tcattatgct tatttttctg
    28081 caatatgtca ggctagaaaa aatgtttata tagaaactcc atattttatt ccagatgaaa
    28141 gtctactaaa agctataaag agtgctgctc ttagtggagt tgatgtgaga ataatatttc
    28201 ctaaaattgc agaccacaag atagtaaata tagcatctta ttcatatttt gaagaaatat
    28261 taagagcagg tggtaaagtt tatttatata ataaaggatt tatacattct aaagtcgtaa
    28321 taatagatga taaaattgct tctgcaggta cagctaatat ggatttaaga agttttatgc
    28381 ttaactttga ggtaaatgca tttatctatg atgaagaagt tattagggta atgacagatg
    28441 atttctttga ggatttaagt cactgtgaag aacttaattt ggaggtattt aagaatagaa
    28501 atatcataca aaaaatcaaa gaatctgtag caagattatt ttcaccaata ttataaaaaa
    28561 ttattaaaaa aggtattgaa aattatgtgt gattggtata ttataataat tgttagcact
    28621 ctattagata gagtgataat aaataaaaag tatatatata aatctacata tataagtagt
    28681 attaatttaa aaataactaa aaacataggc gaactagtct atacttaata ttttaggagg
    28741 cgtgaataat gaaaataaga ccattagctg acagagtagt aattaaaaaa gtagaagcag
    28801 aagaaaaaac tgcaagtgga atagttttac caggagcagc taaagagcaa cctcaaatag
    28861 ctgaagttgt agaagttgga ccaggtggaa tagttgaagg gaaagaaata aaaatggaat
    28921 tgacagtggg agataaggtt atattccaaa aatattctgg aacagaagtt aagatagaag
    28981 gacaagaata cacaatacta agacagagtg atgtattagc tgttattgaa taaatataga
    29041 ataaatttat taggaggggt ttaaaatggc taaagaaatt aaattttcag aggaaacaag
    29101 aagagcttta gaagctggtg taaataaatt agcagataca gtaaaagtaa cattaggacc
    29161 taaaggaaga aatgttatat tagataaaaa atttggttct ccacttataa ctaatgatgg
    29221 agtaactata gcaaaagaga tagaactaga agatagattt gaaaatatgg gtgctcaatt
    29281 agttaaagaa gtagcaacta aaactaatga tgtagctgga gatggtacta caactgctac
    29341 agttttagca caagctataa taagagaagg tttaaagaat gtaacagcag gggctaaccc
    29401 aatactttta agaaaaggaa tacaaaaagc agtaacagta gcagtagaag aattaaaaaa
    29461 tcaatcaaga atagtagaaa cacaagaggc tatatctcaa gttgcttcta tatctgctgg
    29521 tgatgaagaa gttggaaaat taatagcaga agctatggaa atagtaggta aagatggagt
    29581 tataactgtt gaagagtctc aaactatgaa tactgaatta gatgctgttg aaggtatgca
    29641 gtttgataga ggatttgttt ctgcatatat ggttacagat gtagataaaa tggaagcagt
    29701 tttaaacgac ccatatatat taattactga taaaaaaata tctaacatac aagaattatt
    29761 accagttctt gaacaaatag ttcaacaagg taaaaagtta ttgataatag ctgaagatgt
    29821 agaaggtgaa gcattatcta cattagtagt aaataaatta agaggaacat ttgatgtagt
    29881 agcagttaaa gctccaggct ttggagatag aagaaaagaa atgcttcaag atatagcaat
    29941 acttacaggt gctcaagtaa tatcagaaga attaggttat gatttaaaag aagctgattt
    30001 atctatgcta ggtagagctt catctgttaa ggtaactaaa gaaagtacta caatagtaga
    30061 tggttctgga gataaaaaag ctatagaaga tagagtaact caaattaaac atcaagtaga
    30121 gcaaactact tcagattttg atagagagaa attaatggaa agattagcta aacttgctgg
    30181 aggagtagct gttgtaaaag ttggagctgc tacagaagta gagttaaaag aaagaaagtt
    30241 aagaatagaa gatgctctta atgcaactag agcagctgta gaagaaggaa tagtagctgg
    30301 tggaggaact gcttttgtta gtgttatacc agcaatagga acactaattg agagtttaga
    30361 aggagaagtt aaactaggtg ctcaaatagt taaaaaagcg ttagaagagc cattaagaca
    30421 aatagctata aatgctggtc ttgaaggtgc tgtaattgtg caaaatgttg ttaattctga
    30481 agcagaaact ggatttgacg cattgaatga aaaatatgta aatatgatag aagctggtat
    30541 agttgaccca actaaagtta gtagaagtgc tttacaaaat gctgcatcaa tagcaagtac
    30601 tttcttaact actgaagctg ctgttgctga ccttcctgaa aaagaagatg caggaatgcc
    30661 aggaatgggt ggcggaatgc ctggtatgat gtaatttaaa aaatttaaaa tataaatttt
    30721 aatataaaga actatttcga cttagatttt aaactctaag ttgaaatagt tcttttgtat
    30781 atatctaatt tttgtatatc tataaattca atacacatat ttagataatc agtatctagt
    30841 ttgtaataat attttagagt agtattgtta ttttttaggt tatgatttta gatatatatt
    30901 aattaaggta taattgttga tagagaataa atcaaattta aaaggatgcg ataatatgga
    30961 cttaagaaaa ttgcttgaag aagttaaaaa tgaaaatatt gatatagatt ttgcgttaga
    31021 aaagttaaaa gatttacctt atgaagacct tggatatgca aatatagacc atcatagaga
    31081 attaagaaat gggtatccgg aagttattta ttgtgaaggt aagagtgatg agcatatttt
    31141 agggattatt gataaaatga atcaaaaaag ttctaacata ttggggacaa ggtgcagaaa
    31201 agaaactttt ctgaaaatta aagaaatcta taatcatgct gagtacgaag aggcgtctaa
    31261 aattcttaag attcaaaatc atgatataga gaatatagga aaaggtaaaa ttgtgattgc
    31321 tacaggggga acttctgata taccagtagc agacgaagct tatcatacag ctaagttttt
    31381 aggtaatgat gttgatagaa tatatgatgt tggagtggca ggtatacata ggcttttaaa
    31441 taaaagacat aaaatagata gtgctagagt aatagtagcc gttgcaggta tggaaggtgc
    31501 tcttgcaagt gtaattggtg gactggttga tgttccagta atagctgttc caacttctgt
    31561 tggatatgga gcaaattttg gaggattagc agcattacta gctatgttaa atagctgtgc
    31621 atctggaata tctgttgtaa atattgataa tggatttgga gcaggatatt tagcatcaat
    31681 gataaataaa ctgtaaatac attgatataa attaaacaaa actatataat aaaatttaat
    31741 ttctattata tttttactat taaaattgag gagacatata tgagtgaaaa aatactttat
    31801 tttgatataa taagcggtat atcaggggat atgacccttg caagtttatt aaatttaggt
    31861 gtgcctaagg aaattttttt ggaggaaatt cataaactaa gaatgagcga tgaatttaat
    31921 ataaacatca gctcgaaaac tgaaaatgga atagtaggta caaaagtaga agtaattaca
    31981 aaagaaaaac atacacatag aaatttagtg gatatatttg aggttataga taaaagcact
    32041 ctaaacgaaa atgtaaaatc taaagcaaaa aaaatattta tggtaattgg agaagcagaa
    32101 gcaaaagttc atggaactac aatagacaag atacattttc atgaggtagg ggctatagat
    32161 tcaattgtag atatagtagg agcttctata ttagttgact tactttgtgt agataaagtt
    32221 tgtgctagta cagtgtctgt tggttcagga tttgtaaaat gtgaacatgg aattatacct
    32281 atacctgcac ctgcaactat agaaatttta aaaggtgtgc caattaaatt aaataatgta
    32341 aatggagaat gtacaactcc aacaggagct gcaatcataa aagtcttgtg tgatgagttt
    32401 gtagatgagc ttgaattttc tccaaagcaa attggatatg gtataggtca taagaagttt
    32461 gaagtaccaa atatactcag aactgtatta ggtgaaaaaa aaaagaagaa ttaatttatg
    32521 aaattagtgc aaacattgat gatatgtctt cagaaatcta ttcttatttg tatgaaaaaa
    32581 tattagatga gaaagcatta gatatttata cagagagcat ttatatgaag aagaatagac
    32641 cagcaacaaa agtatcaatt ttatgtaatg aatcagattt agaaaaattt attaaaatat
    32701 tacttttaga aactagtact tttggagtga gatataatgc atataataga gaaattttag
    32761 atagaaaatt tgtaaaatta gatacaaaat atggagtggt tacagtaaaa ctaggatatt
    32821 ataaaggaaa actagtcaag gctactccag aatataatga atgtaaaact atagcaaaaa
    32881 atgaagatat tcctataaaa aaagtgtttg ctgatataaa ttttagaata aaagaagaat
    32941 ttagtgaaaa cttattgaca taagtaataa attttgataa attaatattc agccttatta
    33001 aataaaagta aacagaaaaa aatatataaa atataaactc actcgtatat gctcagaaat
    33061 atggtctgag agtctctacc aagataccgt aaatatcttg actatgagtg aaattattat
    33121 accaaaagac ctagttaagt aaatgtgtag gctgagttaa actccctatg tgttggctat
    33181 aagataaagg tattttggaa gcctgtatag taatttcact tttgctagaa attatggaag
    33241 ttactataca ggttttttgt gtaaaaagat ttaatataat ttagactgta ttgtgttaaa
    33301 ataaatatat aaaaactata ttatacaagg agagatgtga atttatgaaa catgaattag
    33361 tacttgtaat agattttgga ggacaatata atcagttgat agctagaaga gttagagaaa
    33421 acaacgtata ttgtgaaata cttccatgta ctgcaagcat agaaagaata aaagaaaaaa
    33481 atcctaaagg gataatattt acaggcggtc caaatagtgc gtatttagaa gattctccaa
    33541 caatatcaaa agaaatattt gaattaggag taccaatact tggaatatgc tatggtattc
    33601 aaataatgtc tcatgtattg ggtggagttg taagaaaagg taataaacaa gaaaaagaat
    33661 atggaaaaac agctataact tatggaaaat catcattatt tgaaggaata actacaaata
    33721 gtgtatggat gagtcataca gatttaatag aaaaagttcc agaaggattt actatagttg
    33781 caaatactaa tgattgtcca gtagcagcta tggaaaatgt agaacgaaac ctatatggag
    33841 ttcaattcca tccagaggta gaacactgtt tggaagggga caagatactt acaaacttct
    33901 tatataatat ttgtaaagta aaaggtgact ggactacaga ttcattcata gaagataaaa
    33961 taaaagaatt aaaagaaaaa ataggcgata aaaaagcttt atgtgcttta agtggaggag
    34021 ttgattcttc tgttgctgca gttcttattc ataaagcaat tggggacaac ttaacttgta
    34081 tatttgttga ccatggttta cttagaaaaa atgaaggaaa tgatgtagaa agaatattta
    34141 gagagaaatt tgatataaat ttaataagag ttaatgcaga agatagattc ttatctaaat
    34201 taaaaggagt ttctgaacca gaagctaaga gaaaaataat aggtgaagaa tttataagag
    34261 tatttgaaga agaatcaaat aaattaggaa aaatggattt cttagtacaa ggaacaatct
    34321 atccagatgt tatagaaagt ggacatggaa atgctgctac tataaagtct catcataatg
    34381 ttggtggaat cccagaagat gtagacttcc aagaaattgt agaaccatta agagagttat
    34441 ttaaggatga agttagaaaa ataggattag agcttggtat agaagaagga ttaatattta
    34501 gacatccttt cccaggacca ggtctaggaa taagagttat aggtgatgta actaaagaaa
    34561 aatgtgatat attaagagaa gctgatgctg tttatatgga cgagcttaga aaagcaggtt
    34621 tatacagaga aatatggcaa gcttttgcaa cattaccaga tgttaagact gttggagtta
    34681 tgggtgatga aagaacatat gcttatttag ttggtttaag agcagttact tcttctgatg
    34741 gaatgacttc tgactggtat aagatgcctt atgatgtatt agaaagaatt tctaatagaa
    34801 taataaatga agttgatgga gtaaatagag tagtttatga tataacttct aagcctcctg
    34861 gaactattga atgggaatag taaataaaaa agtcgtaagc cttgtatttt caaggtttgc
    34921 gacttttaaa aaaatctttg tgatactaaa atgatactat atatttaaat tatctagttt
    34981 ttgggcaact tcaagttgct tatttgggta taaatgtgaa tatgtattcc aagttgtttc
    35041 tactttttca tgccccaatc tttctgctat agttaatata tttacatcca tatttaccaa
    35101 taatgacgca tgagaatgtc tcaaatcatg cactctaatt ctttttacat tagataactt
    35161 acagcatcta tctagctctt tagaaagata acttttagca aatttaaata ttctttcatt
    35221 atcttttaag tcatatagct tagatagata atcttttata ttattatata agaaatgtgg
    35281 gatagggaca acacgtttac ttttaggagt tttaggagaa gaaacaatat cctctccatt
    35341 tagtcttatg tagctttttt cgacgcttat tttattttcg aaaatatctt ttggagtaag
    35401 agctaacaac tcccctagtc taagacctgt ccaaaataaa atttcaaatg ctagtctagg
    35461 ttctgatttc ttttcaaatt caataaattt tttaaactct tctaatgtcc aaaagttcat
    35521 ttcatctgcg ttttttttac cgatagaacc tgccaaatga gcaggattag aaggtaagtt
    35581 ataatattta actgcataat ttaatacagc aacaagctgg ttgtttatcg ttttaatata
    35641 tgtttggcta taatcacttt ttaataattc gttttgccat cttcttatat gtgttgcagt
    35701 aatttcattt atttttagac ttttaaaaaa aggtaaaatt ctaaagttta ttaaatactt
    35761 tttagtttct aatgtagaca attttaatct agaagacata tcgtgcatgt attcttctat
    35821 gagactttca aaactcatat cagtactcat tttagattta ttcaaaaatt ctctttcaaa
    35881 ctctagagct tcttttttag ttttaaaacc tctcttaatt ttctttttcc tatccccatc
    35941 gaagtctgta aaataaaagc tagcatacca actttttctt tgttcgtctt tgtaagcagg
    36001 cattttagac acccccaatt atgtcatttt aatattacaa taattataac atgttagata
    36061 tgctatctaa ataattgttt tattttcctc ttctttttat ttcttgaagc ttgtaatatt
    36121 tacacagttc taagaagtct tcttctagtg ctatagataa gtctaatatc gtagatatac
    36181 ctatatcttt gtactcttga ttttctagtt ttgatatata acttctgtta cgtctcattt
    36241 tttctgctaa ttctagttgt gtcattcttt tcttttttct taattttttc aacatttatt
    36301 aaaatccacc ttttaattat ttttatgaca tttttataat taatagtttg tgtaatttct
    36361 tgtaaaaaat gttcctcatt agaacatttt ttggtggaaa aatgtgttaa aatgtagtta
    36421 agaaattaaa agcaaaaagc actataacaa tagtgctaaa atggtagagt ttaaagaaaa
    36481 aataaatttt atttaaaagc ttataaatat aaagtaaata atttgtaaat taaatctaag
    36541 aataatgtaa aaaatgcaat aaaaaaataa aaattaaaat tatgaaaaat aaagctagtc
    36601 gactaactaa aaatagaaat atacagataa tctaaaatac tagaaataaa aaaataga
//
LOCUS       DAFAZV010000044        35710 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFAZV010000044 DAFAZV010000000
VERSION     DAFAZV010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 35710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35710
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.044"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            238..378
                     /locus_tag="KOU88_002922"
     CDS             238..378
                     /locus_tag="KOU88_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212784.1"
                     /translation="MEKSNTTVTKKEKIEDIGMKLEHLLSEDITFYELLLEILYKEKE
                     EN"
     gene            complement(375..746)
                     /locus_tag="KOU88_002923"
     CDS             complement(375..746)
                     /locus_tag="KOU88_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212785.1"
                     /translation="MESLGDRIANLRKELDINQKELATKVGITEASLSRYENNLREPK
                     SEIIVRLAKALETSTDYLLGVNDNTKISKEDKLIIENLSVSEKTKKLLEKIYSLEKED
                     REAIEKMIDNAYLKRFLKEEN"
     gene            1295..1552
                     /locus_tag="KOU88_002924"
     CDS             1295..1552
                     /locus_tag="KOU88_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212786.1"
                     /translation="MIIIRSQDKTNLMQINQIKIDGSQVYAVFESKIDTVKIGDYENN
                     TRAIQVLDNIQNFIENGTKYDYITSNKVRYNVNKIFQMPAK"
     gene            complement(1662..2342)
                     /locus_tag="KOU88_002925"
     CDS             complement(1662..2342)
                     /locus_tag="KOU88_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBK3212787.1"
                     /translation="MIWTFYSFICVILPCLIYQIVVIKRKNLKVEKNVMIHLVWVYIF
                     LLYIYLALSKAGIGSIWDIGRYSGLFRIDEINLIPFDSVGILTYILNIIMFMPLGFLL
                     PLIWKNFRNIINVSLTGLGFSLAIELCQLFNLRATDIDDLMMNTLGAVLGYFIWVGVN
                     NLFNLIKKKDIFPSIYKNIIQDEIAITIDDDISKKITSLYKNEAIIYLILAVLGEFLL
                     FNWSIIPY"
     gene            2602..2901
                     /locus_tag="KOU88_002926"
     CDS             2602..2901
                     /locus_tag="KOU88_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212788.1"
                     /translation="MKWIKWYSITCICIFIVVAFYMFIFPNKIETIDTSSAYSFVEKK
                     VPNSAVYQGYKKNPVDGTTTIYYSYDNSTHIVRLSHPEDYSRKINWDKVSNIRFD"
     gene            3225..4880
                     /gene="ilvD"
                     /locus_tag="KOU88_002927"
     CDS             3225..4880
                     /gene="ilvD"
                     /locus_tag="KOU88_002927"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBK3212789.1"
                     /translation="MRSDIKKGIEGAPKRALMYGMGLTKEEIERPLIGIVNAQNEVIP
                     GHLHLDEIAEAAKNGVRMSGGLPLEFPAIGVCDGIAMGHVGMNYSLASRELIADSIEA
                     MAMAHGFDALVLIPNCDKIVPGMLMAAARLNIPSIVVSGGPMLPGKKNGKVYDFNSAM
                     EGVGACKDGTVSEEELEALAMNSCPGCGSCSGLFTANSMNCLTEALGMGIPYNGTAAS
                     HSGERKRMAKYAGMYVMELLKNDIKPRDILTIDAFKNAIAVDMAMAGSTNTVLHLPAI
                     AYESGIELNLDFFDEISEKTPCLTKLSPSGKHHIEDLHMAGGIPAIMNELSKINGINL
                     DCKTVTGKTIGENIGNCEIENEEVIHTLKNPYSNQGGLAILKGNLALNGAVVKKSAVA
                     EEMLVHEGPARVFNSEEEAVNAIFGKKINKGDVIVIRYEGPKGGPGMKEMLSPTSAVA
                     GMGLDKHVALLTDGRFSGATRGASIGHISPEAMEGGLIGLVEEGDIISINIPDKKLEL
                     KVDEVEIENRKLKFKPLEPKIKHGYLSRYAKLVTSANTGAVLK"
     gene            5224..5853
                     /locus_tag="KOU88_002928"
     CDS             5224..5853
                     /locus_tag="KOU88_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3212790.1"
                     /translation="MNREEKSKNSKEKIIQSAFSLFSSKGYDSTSTQDIINLSGLSRG
                     AMYHHFKTKEDILRSVTKELYSQMNNFLEHLVADDTLTANEKIIELVVHSANDYTRRK
                     MVHCSWLEKIPFSLIEEVRNLNNVVAPNIAKIIKQGVENKEFSCEYPEELAEMLVFSI
                     DILLDPVLFKREYSEVCNRLDFLLFMLKKMDIPLIDEYGIQKFKDLFKQ"
     gene            5879..6691
                     /locus_tag="KOU88_002929"
     CDS             5879..6691
                     /locus_tag="KOU88_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3212791.1"
                     /translation="MFYNAKSCQMMIGSNTVNYIEFGSGKKTLIILPGLGDGLFPLHG
                     KIQAIAFAFRYKQFAKDYKVYVFSRKNQITEKYSTRDMAKDQADIMKKLGIMKAEVMG
                     VSQGGMIAQYLAIDYPELVEKLVLAVTSSKQNDTIQNVICSWIDMAKKQNYNDLMIDT
                     AKKSYSERYLKKYQLFIPFLGKVGKPKDFKRFIIQATSCIEHNAFSELNKITCPTLII
                     GGANDKIVGNNASFHLAEKIKKSEIFIYEGLGHATYEEAQDFNERVLEFLNK"
     gene            7239..8330
                     /locus_tag="KOU88_002930"
                     /pseudo
     CDS             7239..8330
                     /locus_tag="KOU88_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861958.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
     gene            8329..8740
                     /locus_tag="KOU88_002931"
                     /pseudo
     CDS             8329..8740
                     /locus_tag="KOU88_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            8877..9530
                     /locus_tag="KOU88_002932"
     CDS             8877..9530
                     /locus_tag="KOU88_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3212792.1"
                     /translation="MNNIYSDIYEKLSTLQWIMKRHQMFCQAESGPFADTSRGQGRIL
                     AMLKIQPKIATKELAYLLGIRQQSLNELLNKMEKNGYVERKPSENDKRVMIVHLTEKG
                     KQVQQPKTDYQNIFNCLLPEELLQMSQYLDRIIEAFQLQNGNALEENNMIDWMAQARE
                     RMGDEHFEQLMSMRERAFGHMRPPKDIPGAERFSENYNGYVPDRDGFQPRNFKPDIK"
     gene            9619..10941
                     /locus_tag="KOU88_002933"
     CDS             9619..10941
                     /locus_tag="KOU88_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3212793.1"
                     /translation="MNQKNENYWLLDAPVTKAIWHMAIPMMLGMSINIIYNITDTFFI
                     GRLNDTAALATISLLLPFTTILMAIGNLFGTGGSTLFSRLLGSENTDRTKQCSATTLW
                     LSFLFGLLTAIISIIFSNYIIRLLGADSNTFAYVKQYLIFYGMGAPFIIANFTLEQLI
                     RGDGKSVESMIGMMISIGANIILDPILMFGLQLGIRGAAIATVIGNAFAVIYYIVCIQ
                     RADNQLSALPKYFRLEKQMLKEIFLVGLSAMLLDILLIVSSLMFNYYALKYGDYVLAG
                     FGISQKLVQIVDLIGMGLYMGVIPLIATAYGARNELRVKEIIKKTALYLALVITCLFT
                     ILFTCRNFIVHCFSNDSDVIRIGAYILTVQLCSSFFAAGAGLLTGIFQAKGEGTPAVV
                     MSVMRGIMLIPAIIFGNYLFKMNGVIFSLLVAEAISCITGLVLYKLKK"
     gene            11054..11265
                     /locus_tag="KOU88_002934"
                     /pseudo
     CDS             11054..11265
                     /locus_tag="KOU88_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393106.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(11363..11722)
                     /locus_tag="KOU88_002935"
     CDS             complement(11363..11722)
                     /locus_tag="KOU88_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212794.1"
                     /translation="MRKKKDTHSFDFRPLGLAIREAREKAGLSRNDLGDKVFYGERHI
                     ADIENIGKHPSFHLFHDLVTMFNISVDEYFYPAKNVEKSTVSRQIDSSLDLLSDDELK
                     IIQGTIDGILNSRENKK"
     gene            12046..12420
                     /locus_tag="KOU88_002936"
     CDS             12046..12420
                     /locus_tag="KOU88_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001129922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TnpV protein"
                     /protein_id="HBK3212795.1"
                     /translation="MAKTIFEELGGKYERQGDYLIPCLTVPAEEEQPIGTWGQRHLDY
                     LKQYRKVTYTNLLTSGRLNTYLADIDRQAQERFERLIEGMKQAQGITERLKEENALEW
                     TGRMNNIRACAREIVNEEIIFA"
     gene            12664..13587
                     /locus_tag="KOU88_002937"
     CDS             12664..13587
                     /locus_tag="KOU88_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006782058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212796.1"
                     /translation="MKNVYKLEFHSGSKEELLPDFESEFPYIASNAELDKYIGRSAPW
                     HWHRAIELFYMESGTLEYYTPKKKLSFSAGSGGFINSNVLHMTKAVSRTEKNIQRLHI
                     FDTALISGNYGSKIEKKYVMPITANPQIEIYAFRPDNFIHADILDLIKQTFTLCENDI
                     GYEIKIRESLSRIWLKLFELFSASFDGKGKYDKNDERLKKMLIYIHEHFADKIAVSEL
                     ATVACLSERECFRLFQSYLHTTPTKYIQSYRLQEACEMLINGQDTITDIGHACGLGNS
                     SYFSKIFREYQNCTPIEYRKKWQDSHILCPK"
     gene            13663..14253
                     /locus_tag="KOU88_002938"
     CDS             13663..14253
                     /locus_tag="KOU88_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004056524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBK3212797.1"
                     /translation="MFYEAKDFLETADKETLHIISNARKLTREYYFTDYDNTKRKNEI
                     LKELLGAVGKNVAIDVPLHCDYGKNVFLGDDVVINMNCTFVDNKPIRIGSRVLIASNV
                     QFYTSSHPVLPQERFVSDWEETGTTFFRTYARSIEIQDNVWIGGGSIILAGVTIGENS
                     VVGAGSVVTRSIPANCVAVGNPCKVIRCFTEKRGKA"
     gene            14253..14873
                     /locus_tag="KOU88_002939"
     CDS             14253..14873
                     /locus_tag="KOU88_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016304801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK3212798.1"
                     /translation="MKYQHIVFDIDGTLINTEHAILHSLQDTLEECIHEKVPVKQLLF
                     VMGITGEDALRQLKINNIPLSLKLWEENIKKYSNTITVYDGIQELLNSLSECDCKIGI
                     VTSKTKAEFKDDFDRFGLKHYFKTIICADDTTGHKPSTEPLLKYIEISGAYNEQILYI
                     GDSKYDSLCAKNAEVDFALAMWGSHTRELEADYFIETPNDLLGAIK"
     gene            14915..15112
                     /locus_tag="KOU88_002940"
     CDS             14915..15112
                     /locus_tag="KOU88_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006863419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBK3212799.1"
                     /translation="MNIEKWILCPVCGGKTRNKIREDTVLINYPLYCPKCRQESLIVA
                     KNMQISIVIEPNAHTYKAVNY"
     gene            15144..15764
                     /locus_tag="KOU88_002941"
     CDS             15144..15764
                     /locus_tag="KOU88_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008751343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK3212800.1"
                     /translation="MDNNEKWLQWAVELQSLAQAGIFYGKDVFDKERYERIREIAAEM
                     ISYKSEISMDKVKNLFCNEIGYQTPKIDCRAAVFQNNKILLVQEKNGTWSLPGGWVDV
                     NVSVKENVMKEVKEEAGLDVMADMVIAVQDREKHNLPVYAYKVCKIFILCSVIGGEFK
                     SNIETISSNYFGMNELPILATEKNNEEQIKMCFEAYQSENWKTFFD"
     gene            16346..16813
                     /locus_tag="KOU88_002942"
     CDS             16346..16813
                     /locus_tag="KOU88_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004054879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3212801.1"
                     /translation="MELSYTDFCRRRQADQSYMDKLFIPVQGCLLEVVREQYADFYKE
                     KERWRYLKKLDTNHKLLSLEGFTDSEGNVLDFVIDETVDVAETVVHAVMVDSLKAALS
                     LLSGREQALINAIFFEELSEREVGLRLGVTQSVVNKRKSKILAKLRKIIENKI"
     gene            16902..17327
                     /locus_tag="KOU88_002943"
     CDS             16902..17327
                     /locus_tag="KOU88_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3212802.1"
                     /translation="MAYNHGREDRKWRIWKEAEEKILRECGVDEETIEQIRTDDRADF
                     NSNRRFYRWASDFGEYLEGMADREKQAEVKSVSDLLDEIEDETLYLALVTVDRRTLQI
                     VLLKMQGYSTKEIAPLVHLTAGAVYARLNHLRKKLRKIL"
     gene            17410..17883
                     /locus_tag="KOU88_002944"
     CDS             17410..17883
                     /locus_tag="KOU88_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3212803.1"
                     /translation="MAYGAKTYKLREESTESGARYFISFKDGQREHHELEVSEQLFIE
                     FRQMERRNRNLQQWNQRHREFNEVWDETLYRRALRVPKTLDERMIEKERNEMFLKAVA
                     RLPEIQRRRFLLYYEYDFNFYQIGAMEHCTASAVQKSVSVAREKVKAEMRKYLQS"
     gene            18034..19065
                     /locus_tag="KOU88_002945"
     CDS             18034..19065
                     /locus_tag="KOU88_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015512777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3212804.1"
                     /translation="MQKLQTVNADTLLYEPLEKPSFVVDGLIPTGLTLFCGSQKIGKS
                     WLMLKLCLCVSQGIPLWDMPTREGDVLYLCLEDTFCRIQDRLFRLTDEASGRLYFAVA
                     SDKLSDGLIVQLEDYLKEYPDSRLIVIDTLQKVRTASKDNAYASDYGDISLIKDFADR
                     HSLAVIVVHHIRKQNDSDVFNKVSGTTGLTGSADATFVLEQESRASNAAKLYVTGRDT
                     PYQEFTLRFRDCSWELVERKEQEQLAKEAIPDVLFRLVDFMQDKEEWTGTATELLAAM
                     GETETVPTVITKWLNEYRTTFLSENHICYQYSRKKDGRQIALARQTGDSGDSDDSGIG
                     IPPVTVIDT"
     gene            19589..20554
                     /locus_tag="KOU88_002946"
     CDS             19589..20554
                     /locus_tag="KOU88_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HBK3212805.1"
                     /translation="MPYAILRFQKRKAGGVAACERHNERKKEAYKSNPDIDMERSKNN
                     YHLIAPPKYTYKKEINRMVAEAGCRTRKDSVMMVETLITASPEFMNQLPPEEQKEYFQ
                     TALDFISERVGKKNILSAVVHMDERTPHMHLCFVPLTPDNKLSAKSILGNQKSLSEWQ
                     TAYHERMFARWSELERGQSSMETKRKHIPTWLYKLGGRMDKQYEEIVSALSDINAFNA
                     GKKRDKALELLSAWLPDVEKFSKEISKQSAYIDSLKERIGQESDYAGRMRDEKYEQER
                     KVQKANQRIFELQKTNQQMERLLKKIPPEVLEELQKSNRNRARER"
     gene            20563..21417
                     /locus_tag="KOU88_002947"
     CDS             20563..21417
                     /locus_tag="KOU88_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002596257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBK3212806.1"
                     /translation="MKKQDFKVLKTADLYPFPDNPFHVVEDEMLSELAESIKEFGIVT
                     PIITRPKEDGNGYEIIAGQRRVRASELAGINTIPAFVLPLDRDRAIITLVDSNLQREN
                     ILPSERAFAYKMKSEAMKRQGFRTDLTSSQVGTKLRTDDKVAQGFGVGRMTVQRFIRL
                     TELIPPILQMVDEGKIALTPAVELSFLKKGEQENLFATMESEEATPSLSQAQRMKSLS
                     QSRRLNMDAIFAIMTEEKGNQKETVKIGMERLKKYFPKGTTPKQMEDTIIKLLERELQ
                     RKRGRDSR"
     gene            21496..21726
                     /locus_tag="KOU88_002948"
     CDS             21496..21726
                     /locus_tag="KOU88_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212807.1"
                     /translation="MKEIQYEIVKEIAVLSTSESGYTKEINLISWNGKEPKYDIRSFS
                     PNREKCGKGITLTADEAAALLKALQEELNSGD"
     gene            21798..21989
                     /locus_tag="KOU88_002949"
     CDS             21798..21989
                     /locus_tag="KOU88_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein R"
                     /protein_id="HBK3212808.1"
                     /translation="MGEDKKANKKRKRIVARQPVQMIVSREYVGTQTVAEAFIPIISE
                     DIRRKIAEGDTFDNEDISA"
     gene            22044..23903
                     /locus_tag="KOU88_002950"
                     /pseudo
     CDS             22044..23903
                     /locus_tag="KOU88_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006567773.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            24520..25458
                     /locus_tag="KOU88_002951"
     CDS             24520..25458
                     /locus_tag="KOU88_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family peptidase"
                     /protein_id="HBK3212809.1"
                     /translation="MNKRMKLIPYEINENLRGAKNKFPYGIKQMNARGMWDEGYTGKN
                     IVVGIIDTGCDISHPLLKGKIIGGANFSDDSNGNKNIYEDFNGHGTHVAGIIAASNYN
                     NEVMGVAPDCKLLIAKALNKDGTGTYQSIINAINFAVNNKVDIISMSLGGNKDDKNLK
                     NAVMQAVKNNISVVCAAGNNGDGDSSTSEYSYPASYAEVIEVGAINENYLVEKFSNSN
                     TTIDLVAPGRNIISTYMDNKLAIMSGTSMSAPYVSGSLALIKEWAREEFERDLDEAEL
                     YAQLIKCTRALGIPRTEQGNGYLYLNLYKYKNNSKR"
     gene            25934..26362
                     /locus_tag="KOU88_002952"
     CDS             25934..26362
                     /locus_tag="KOU88_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBK3212810.1"
                     /translation="MSKIYIVYWSGTGNTEKMANFVAEGVKLKGKTPEVLDVSLLKPS
                     DLKEEDKFALGCPSMGAEQLEEGDMEPFVSELESMVSGKQIGLFGSYGWGNCEWMRDW
                     EERMQNAGATIIGGEGITAMEDPNEEAKDECIELGKTLAE"
     gene            complement(26515..26721)
                     /locus_tag="KOU88_002953"
     CDS             complement(26515..26721)
                     /locus_tag="KOU88_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212811.1"
                     /translation="MISHAAEICKKYKMPFIIFPTIEKKSIEEWVNIGANMLCLAQDT
                     TFITYVINQLLSFYNEIVPIQKQH"
     gene            27043..27699
                     /locus_tag="KOU88_002954"
     CDS             27043..27699
                     /locus_tag="KOU88_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3212812.1"
                     /translation="MTRKNNPKQAIENIITISAKLFAEKGYDKTSMQNIVDASGMSKG
                     GIFHHFSSKEDIFNVVMERRFEQIIETVNQWLGEMHGLTAKEKLRSLVRRHLTDEVIK
                     ESSNMITSAIESPHIILAFTQDNLKKLAPILANVLREGIEDRSIITEFPDECAEVILL
                     LFNFWCDTDVFQGDFPTIRKRFQFLQFLMRQIGVDILEDEIIESINIFYERKPMGQVE
                     "
     gene            27783..28862
                     /locus_tag="KOU88_002955"
     CDS             27783..28862
                     /locus_tag="KOU88_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3212813.1"
                     /translation="MILITLCILVAVFVLAFAGLRLIAPTIIRTSHKIEAPGIDRMEM
                     VEIGGIQQALYIRGQNADNPIILWVHGGPGNSMMPFLHLYQYEWENDFTVVNWDQRNV
                     GKTYFANDPAAVLQTMSAERVLQDVHEVTAYLKQQFNKEKIILIGHSWGTVLGTMAVQ
                     TYPEDYSAYIGIAQTVNMVDNERVGYEKTLEMVKAAGKQKDIKALEAVAPYPPAKYGP
                     SYLAALMTVRTYQSKYGLSINMDLGNIISILATPYYSLSELKNTTIVNPNAIDNQGDV
                     LRFLVEEADIRNYGVDYQVPVYYIMGENDYNSPYLPAKKFFDEIVAPDKQIFFIPDAD
                     HLPFLSKKAEFDCILLEEIAPKLAK"
     gene            30134..31789
                     /locus_tag="KOU88_002956"
     CDS             30134..31789
                     /locus_tag="KOU88_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212814.1"
                     /translation="MVDFIESNNEVQKFDWGEVMWIHEPSKTQFNRLSAGIVRFFPGN
                     CQEKHFHLSEEQLLYVIQGEGIQIIDGKKVNIKETSIVYCPPYSEHEIINTGKIDLVI
                     LITYVPHKFSSLRQIPIVFSENNIQELVNVNIIENLANQISNILKLRISVYDLKYKEI
                     FETKKENKFCDICKNIKPCTKKLVKSINNDNFEKVYHCEYGVSSLEIPIVLEENIVGY
                     IECGNFIVYKSIYIDKNLSELSSSSGIDIKYINKIYNEFPLNPKSRLYVLKENLLMMS
                     EFIQEIAKRNFFENQLSIKDEEILKSRKENIRLEEALKKANSRLLEEEYIINPIDMFN
                     NSSKEYPFELELYIEKEIKNMNLEGVYNLIDTNKLRYNDVRDTIQEMIFVLSRTVLRD
                     LEDLKLISYLRNKYNKKISLVNSDEDLWNVLFEFSKECIDKNRAFWRKDKGNLIENIN
                     EYIKKYYKENINLNSISDVFFISPNYLSSIFNERNKVSITEYINLLRIEESKKYLLDR
                     SMSISDICKKVGFNNSSYFSQIFKKFNSITPNEYRKNMLDNKY"
     gene            31848..32600
                     /locus_tag="KOU88_002957"
     CDS             31848..32600
                     /locus_tag="KOU88_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HBK3212815.1"
                     /translation="MFSVIFLCIGGFLAAFVDSIAGGGGLISMPVLMAIGVPVHLAIG
                     TNKFAASAGCISSAYRYAKSGKINNNLLKKLVPFTIIGSVLGVRCVLSISEEILNVLV
                     VVMILIVAIYTFISKNLGQEDNFEAVNKKNLRLGMLMALIMGFYDGFFGPGTGTFLTF
                     GFIKIYGYDFLHASANTKILNLTSNITSLLLFMINGQVDYKIAIVFALVMIMGAYVGA
                     KVAIKKGSKMIKPIFLVMALFMVVKLVYQTLV"
     gene            complement(33116..33175)
                     /locus_tag="KOU88_002958"
     CDS             complement(33116..33175)
                     /locus_tag="KOU88_002958"
                     /inference="COORDINATES: protein motif:HMM:NF024729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBK3212816.1"
                     /translation="MTEYIYYYNNKRIKKINLA"
     gene            33568..33861
                     /locus_tag="KOU88_002959"
     CDS             33568..33861
                     /locus_tag="KOU88_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK3212817.1"
                     /translation="MGFPETFKALSDPIRREILVMLRENKMSAGEISEKFNMTNATIS
                     YHLSQLKKAGLIFETKYKNFIFYEINISVFEEVMLWFSQFMEKGEKDNEKSDK"
     gene            33842..34483
                     /locus_tag="KOU88_002960"
     CDS             33842..34483
                     /locus_tag="KOU88_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBK3212818.1"
                     /translation="MKKAINKQFILSTLICFIPFIVSIYFYNRLPNEVAIHFDNYGNP
                     DNYAPKVIAAFGVPLLMLCIHLYTWFRLENEPKKANFSNVIQNLSKWGVAILSVIIQI
                     MMVLYSTGVSLESNFYTGLILGIIVILFGNYLPKCKRNYSVGIILPWTLNDEDNWNKT
                     HHLAGWIWLIGGILLIINAFINIPFYNIFVIFVIVILPFIYSYLMYKISGKNN"
     gene            34727..35059
                     /locus_tag="KOU88_002961"
     CDS             34727..35059
                     /locus_tag="KOU88_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBK3212819.1"
                     /translation="MNTREMKEYRVFYNKKLSETDEFFRVFGSLDDKTYSEGAISKKN
                     KELMGLAISILSRCDECICYHIEGCINSGASKDEIIEAIKIGVIGGGSITYPNARFAI
                     KILEEFNI"
BASE COUNT        12672 a         5230 c         7192 g        10616 t
ORIGIN      
        1 aatagaaaaa acatacaaga ttctacaata atagattttt ttgttattat tacgagtttt
       61 ttattgcaac tgtagaataa aagtattatt atataattaa gataattatc tagggaaatt
      121 ttggataatc aaaatatatt ttataaaatc aaaatacaat tacataaact ttattaaaaa
      181 tttgttggga atttctgact aacattaaga acgtaagttt gttgggggat ggtatatgtg
      241 gaaaagtcaa acactactgt tacaaaaaaa gaaaaaattg aagatatagg aatgaaatta
      301 gaacatttat tgagtgaaga tattactttt tatgaattat tacttgagat tttgtataaa
      361 gaaaaagaag agaattaatt ctcttcttta aggaatcttt ttaaataggc attatcaatc
      421 attttttcta tagcttctct atcttctttt tcaagagaat atattttttc taagagcttt
      481 tttgtttttt cacttactga taagttctct atgattaatt tatcttcttt gcttattttt
      541 gtattatcat ttacgcctaa taaataatct gttgatgttt ctaatgcttt tgctaatcta
      601 actattattt cacttttagg ttctcttaaa ttattttcat aacgtgacaa gctagcctca
      661 gttataccga ctttagtagc aagttctttt tgatttatat ctaattcttt tcgtagattt
      721 gctattctat ctcctaaact ttccatatgt acatcactcc ttaccgaaat tataagttat
      781 tttgataaaa agtaaaataa aattaccaaa aatataaaaa aaaaaggtta aaataataaa
      841 atatattgaa aattaccatt tgtatatgta taatatgaat tatacaaatg gtaatttgat
      901 gagaggtggt atgttgaaat aagaaactga attaattaat aaatacatag aaagttttga
      961 aaacctttaa ttgagatata aacaatatgt acaaaatttt ttgcaagtaa aattaccaaa
     1021 tgtataaaat aaatcagtag catagataat tttatgcttt aatacattag attatttaat
     1081 ttagttataa tggtcaaaaa tgcaatctac aaataaaaca aagtattatc aaaaaagtat
     1141 tctttaagaa aattttttat tagagatgta attgatataa ataatcgtat taaaaaataa
     1201 aatactaagt ttaaaaattt aaataatcta taaatcaatt ataaaatatt atttattaga
     1261 aattaaaatg aattaagtaa atggaggaat tgatatgata ataattagaa gtcaagataa
     1321 aactaattta atgcagataa accaaattaa aatagatggt agtcaagttt atgcagtatt
     1381 tgaaagtaaa attgatactg taaaaatagg agattatgaa aataatacaa gagctataca
     1441 agtgttggac aatatacaaa acttcattga aaatggaaca aaatatgatt atataacatc
     1501 aaataaagtc agatacaatg ttaataaaat atttcagatg ccagctaaat agtgagtgtg
     1561 cattttaatt taataactaa agcccacttt cttttgtagt atgaaagagg gctttacata
     1621 tttgtaaata tcgaagtaca cttattttat caataaatta tttaataagg tataatggac
     1681 caattaaaca ataaaaattc tcctaaaaca gcaagtatta aatatataat agcttcattt
     1741 ttgtaaagag aggtaatttt tttgcttatg tcatcatcaa ttgtaatagc aatctcatct
     1801 tgaataatat ttttatatat agatgggaaa atatcttttt tctttataag attaaataaa
     1861 ttatttacac ctacccatat aaaatatcct aaaacagcac ctaatgtgtt catcattaaa
     1921 tcatcaatat ctgtagctct taagttaaac aattgacaaa gttcaattgc taatgaaaaa
     1981 cctaatccag ttaatgaaac attgataata tttctaaaat ttttccaaat taaaggtagt
     2041 aaaaatccta aaggcataaa cataattata tttaaaatat atgttaagat gccaactgag
     2101 tcaaaaggta ttagatttat ttcatcaatt ctaaaaagcc cactatacct tcctatatcc
     2161 catatgctac caattccagc tttactaagt gctagataga tatataataa aaaaatatat
     2221 acccatacta aatgtatcat tacattcttt tcaactttca aattttttcg ttttataacg
     2281 actatttggt atattaagca tggtaatata acgcaaataa atgaataaaa tgtccatatc
     2341 attttatttt gtcccctttc aaatttatgt ttttagtttt ataagtacta tctttatatt
     2401 aaactgtaag ttttaaaaat cttttaataa aatcttaaaa atttattaat ttataaaaat
     2461 atattattaa gattaaaaaa tatatataat caaagtttct acaattatat agttagggat
     2521 ataaaaattt tatcgtatgc ataaatatta taaatatatg gaaataataa tagtatattt
     2581 tggtaaagta ggaggaattt tatgaaatgg attaaatggt atagtattac atgcatatgt
     2641 atttttatag tagtagcttt ttatatgttt atatttccta ataaaataga aactattgat
     2701 acttcatctg catatagctt tgttgaaaag aaagtaccaa atagtgctgt gtatcaagga
     2761 tacaaaaaga atccagttga tggtactact acaatttatt acagctatga taattcaact
     2821 catatagtta gattatcaca tccagaagac tattcaagga agattaattg ggataaagtt
     2881 tcaaacatca gatttgatta atctttaata tttataaaag tctatatatc taaggcaaat
     2941 atattattaa tcttattcat agttgagcac tttctattat agaagtgcct cttctgattt
     3001 atatcataaa atattactca acaatttgta aaatatatta gtttataaaa tatattgaaa
     3061 agataatatt atataatacg attgtgtaag atattgataa aaaatcgtaa taaattttca
     3121 ttagtatatg ctaatatttt tttacaattt tcgtaattaa ttaatagaaa aatatattat
     3181 aataatatta tgaaaattta aaaaagtaag aaagaggtaa tattatgaga agtgatataa
     3241 aaaaaggaat agaaggagct ccaaagagag cgttaatgta tggaatgggt cttactaaag
     3301 aagaaattga aagaccatta ataggtatag taaatgcaca aaatgaggtg attcctggtc
     3361 atctgcatct tgatgaaata gcagaagctg caaaaaatgg agtaagaatg agtggtggtt
     3421 tgccattaga atttcctgct ataggggtat gtgatggtat agctatgggg catgtcggaa
     3481 tgaattattc cctggcttca agagaattaa tagcagattc aatagaagct atggctatgg
     3541 cacatggttt tgatgctttg gtacttatac ctaattgtga caagatagtg ccaggtatgt
     3601 taatggctgc tgcaagactt aatataccaa gtattgttgt gagtggaggg cctatgcttc
     3661 caggtaaaaa aaatggaaaa gtatatgatt ttaactctgc aatggagggt gttggagcat
     3721 gtaaagatgg aacagtaagt gaagaagaat tagaagcgtt agccatgaac tcttgtcctg
     3781 gatgtggttc atgttctggt cttttcacag caaatagcat gaattgttta acagaagctt
     3841 taggcatggg gataccatat aatggtactg ctgcgtcaca ttctggagaa agaaaaagga
     3901 tggcaaaata tgcaggtatg tatgttatgg agttacttaa gaacgacata aaacctagag
     3961 atattttaac aatagatgct tttaaaaatg ctatagctgt ggatatggca atggctggtt
     4021 ctacaaatac agtacttcac ttacctgcaa tagcttatga atcaggaata gagcttaact
     4081 tagatttttt tgatgaaata agtgaaaaaa ctccttgttt aacaaaatta agtccaagtg
     4141 gaaaacatca tattgaagat ttacatatgg caggaggaat accagctata atgaatgaac
     4201 tttcaaagat aaatggaata aatttagatt gcaaaaccgt aacaggcaag actatagggg
     4261 aaaatatagg aaattgtgaa atagaaaatg aagaagtaat acatacatta aagaatccat
     4321 atagtaacca aggtgggctt gcaatattga aaggaaatct tgctctaaat ggagctgttg
     4381 taaaaaagtc agcagttgca gaagaaatgt tagttcatga aggaccagca agagttttta
     4441 attcagaaga agaagctgta aatgctattt ttggtaaaaa aataaacaaa ggtgatgtta
     4501 tagttataag atatgaaggt ccaaagggtg gtccaggaat gaaagaaatg ctatctccta
     4561 catcagcagt tgcaggaatg ggacttgata agcatgtagc acttcttact gatggtcgtt
     4621 tttcaggggc aactagagga gcatctatag gccatatttc tccagaagct atggaaggtg
     4681 gtttaatcgg gttagttgaa gaaggagata taatttctat aaacatacca gacaaaaaat
     4741 tagagttaaa agtagatgaa gttgaaatag aaaatagaaa attaaaattt aaacctttag
     4801 aaccgaaaat aaagcatgga tacttaagta gatatgctaa attggtaaca tcagcaaata
     4861 caggagcagt tttaaaatag tagactatat ttatgtaaat tagaaaaagt taagaaaata
     4921 ttaattggat atcttaggtg ttatagcact aatgaggtat cctttttatt ttgtatgaaa
     4981 aacacagcaa aatcttgatt atctttgaaa acaatacatc tctattataa ggaatacgag
     5041 tacagcatag agatgtatct tttagacctt gtttaggtaa tacaactttt taaaagtttg
     5101 atgtggaatg cttttcgttc catctgaact atgaagaaat tgaaagtcag ttaattcttg
     5161 acataataaa tattaaaatg tataataaaa aacaaacaga cagtctgttt ttaggaggga
     5221 aatatgaata gagaagaaaa aagtaaaaat agtaaagaaa aaattatcca atcagcattt
     5281 tcactatttt cgtctaaagg atatgattca acatctacac aagatattat caatttatct
     5341 ggtctatcta gaggtgcaat gtatcatcac tttaaaacta aagaagatat actgagaagt
     5401 gtcacaaaag aactttactc acaaatgaat aattttttag agcatcttgt tgctgatgac
     5461 acccttacag caaatgaaaa aataatagaa ttggttgttc atagtgcgaa tgattacaca
     5521 cgtagaaaaa tggtacattg tagctggtta gaaaaaatcc cattctcttt aatagaggaa
     5581 gttcgtaatc tcaacaatgt agttgcaccc aatattgcta agataattaa acaaggtgtt
     5641 gaaaataaag aattttcttg tgaatatcca gaggaattag ctgaaatgct cgtttttagt
     5701 attgatattt tacttgaccc tgtattattt aaacgtgaat acagtgaagt atgtaatagg
     5761 ttggattttt tattattcat gttaaaaaaa atggatattc ctctaattga tgagtacggt
     5821 attcaaaaat ttaaagattt atttaaacaa tgataatagg aaaagtgagg aatagactat
     5881 gttttataat gcaaaaagct gtcaaatgat gataggaagt aatacagtga attatattga
     5941 atttggtagt ggtaagaaga cactaattat tttaccagga ttaggagatg gtttatttcc
     6001 tttacatgga aaaatacaag cgattgcttt tgcttttaga tataagcaat ttgcaaaaga
     6061 ttataaggtt tatgtattta gtagaaaaaa tcaaattaca gaaaaatatt ccacaaggga
     6121 tatggctaaa gaccaagcag atataatgaa aaaacttgga attatgaaag cagaagtaat
     6181 gggtgtttct caaggtggaa tgatagctca atatctggca attgattatc ctgagttagt
     6241 tgagaaactt gtgttggcag ttacttcttc aaagcaaaat gatactatcc aaaatgttat
     6301 ttgtagttgg attgatatgg cgaagaagca gaattacaat gatttaatga ttgacacagc
     6361 aaagaaatcc tattctgaaa gatatttaaa aaaataccaa ttatttattc cttttttagg
     6421 aaaagtaggt aaaccaaagg attttaaacg atttattatt caagcgacct cttgcataga
     6481 acataatgcc ttttccgaat taaataaaat aacatgtcca accttaatta taggaggtgc
     6541 taatgataaa attgttggaa ataatgcttc ttttcattta gcagaaaaaa ttaaaaaaag
     6601 cgaaatattt atctatgagg gattgggaca cgctacatat gaagaagcac aggattttaa
     6661 tgaaagagtt ttagagtttt taaataagta aacacctttg ttaaaaatat acatatgaag
     6721 attggaaatt taatgttaaa aatagaaaca tgaaaatatg cttaactggt atttttacta
     6781 ttcataacca atttttgata cattatctac tataaataca aatatagctt caatgtgatt
     6841 atatattggt gtattggtaa agcacttata caaacagagg aattttgtaa attcatatta
     6901 tacccacatt tgttaactta tgaaaatata atcaaaattt ttatgagatt tttatataaa
     6961 aaacgcccta aaaatcttat tatccccata aacactgtat ctaaaagcat attcaatagg
     7021 aaataaatcg tgatattact acgaatttac tactaatgaa tgagccttga tacgtcttat
     7081 ttcccagata tgcaaagata tggcatggca catcagtaaa aattgaatac ttatatagac
     7141 tatggaacgt acacttttgg cgtttctttt ctatttccag atgttctttt cagagcgtct
     7201 ttttttcata cccaaaatcg aaaggagaaa gagaaaatat gaataagcta gtaaagcgat
     7261 tgctgacagg gacgctcgcc attgcaacca ttcttaccgc attgcctgtg acggtggttc
     7321 atgcttctgg caatcaatac tggacagaat cagcagaacg tgtcggctac attgaacatg
     7381 ttatgaatga tggttctatc aaatccacat taaatgaggg acacatgaaa gttgagggcg
     7441 aaactgccta ttgcgtggac atcaatacaa atttcaaaaa tggatataaa acaaggtatg
     7501 acgcaagctc ccatatgagt agcgatcaga ttgcggacat tgctctttcc ttagagtaca
     7561 tcaagcaata tactgcttct catacaaact tgaattacaa gcagggttac ttattggaac
     7621 agtgtgttgt ctggcagaga ttgagtgaac agctcggctg gcaatgtgat aacgtcagag
     7681 cttcctataa tgaaatctca caggcggtac agaataaagt ttacgctggt gcgaaagtat
     7741 ttgtgaaagc aaataaggga tgctatgaat gtggcggtta catctacact ggcgaaggac
     7801 aggacattgg acagttctgg gcgaagttga atgtgggaaa tgaaaaggtc aaaaagactt
     7861 cttccaattc caccctctac agatggcaat gtcaattatt cctttgaggg ggcaacattt
     7921 ggcgaatccc atattgtagt cacagataaa aacggtcagt tctctactgc ttcaagttgg
     7981 gctttccgta aggtaaatac aaatgctgga aaatccagtg aggatggtgt atggtttggt
     8041 acttctgaac cagacgacag taaaggtgca ttacctatgt gattgaggaa ttaaagtgtg
     8101 attccaacgc cggatttaag ctgattccag cttttgaggt ggtcgtatcc agaaaaaaag
     8161 tgaccgtaga tttagggaca cttactgatg aatatgaaaa agaaatcaca atccatacca
     8221 cagctaccga caagaaaaca ggcgaaaaaa tgattgttgc cggaaaagac atcaagatcg
     8281 tggacaaagt cacacttgat ggcttggaaa ctggcagtca cagaaaatta caccgtgacc
     8341 gttcatgtgt atacagatgg tgaaatgggt cattacccag aatcctaccc ttgctccggt
     8401 ggtacagaaa tcaaagtatg aaccgaaagc acagggagca gatgtcagcg tcagctccga
     8461 tacgttcaaa gacgctacta ctttcttgga aacattcttt aaactctatc cgacagctac
     8521 agaaaaagaa cttgcctatt atgtcaaaga cggtgtgctt gctcctgttt ctggcgacta
     8581 tgtattttcg gaactggtaa atcctgtctt taccaaagat ggcgataatc tcaaggtcag
     8641 tgtgtccgtg aaatatctgg ataacaagtc gaaaatgaca caaatctcac agtatgagct
     8701 tgtgcttcac aaggacgata attggaaaat tgtaggataa atattacagc agaccagcta
     8761 tgacaatttc aaatacatat actaagtttt aaaaatatac atgtacccta ttgacttttt
     8821 gggaaggtac ctgtatatta tttgttaaag gtacctgttg aaaaggaggt catactatga
     8881 ataatattta ttctgatatc tatgagaaac tatcaacctt gcaatggatt atgaaacgcc
     8941 atcagatgtt ttgtcaggca gagtctggtc catttgctga tacatcacga ggacaaggaa
     9001 gaattcttgc tatgttaaaa attcagccaa aaattgcaac aaaagagttg gcatatttat
     9061 tgggaatacg ccaacaatcc ctaaatgagt tgcttaataa aatggagaaa aatggctatg
     9121 tagaacgaaa accatctgaa aatgataaac gcgttatgat tgttcatttg acagaaaagg
     9181 gaaagcaagt tcagcaaccg aaaacagact atcaaaatat ctttaattgt ctacttccag
     9241 aagaattgct acaaatgtcg caatatttag atcgtattat tgaagctttt caattgcaaa
     9301 atggaaatgc tttagaagaa aacaatatga ttgactggat ggctcaggca agagaacgta
     9361 tgggcgatga gcattttgaa cagttaatgt ctatgcgtga aagagctttt ggacatatga
     9421 gaccacccaa agatataccg ggagctgaac gcttttctga aaactataac ggatatgttc
     9481 cagatagaga cggatttcag ccaagaaact ttaaaccaga tatcaaataa caaaaggcac
     9541 tgtaaaatta cagcaataag ccctatggag attttttgaa ctccataggg cttatttttt
     9601 gaaaaggaga cgaacaaaat gaaccagaaa aatgaaaatt actggctttt agacgcacct
     9661 gtcacaaaag ctatatggca tatggcgatt ccaatgatgc ttggaatgtc aataaacatt
     9721 atttacaata ttacagatac attcttcata ggcagattaa atgacacagc ggctcttgcc
     9781 acaatctcac tgctgttacc tttcacgacc attttaatgg caattgggaa tttgtttgga
     9841 acaggtggaa gcactttgtt ttcacgactg ttaggaagtg aaaatacgga caggacaaaa
     9901 caatgttcag ctacaacatt atggctatct ttcctgtttg gactattgac tgcaataata
     9961 tccatcattt tcagtaacta tattatccga cttctcggtg ctgatagtaa tacttttgcc
    10021 tatgtcaaac agtatcttat tttttatgga atgggtgctc cgtttattat tgccaatttt
    10081 acgctagaac agttaattag aggtgacggt aaatctgtag aatctatgat tggaatgatg
    10141 ataagcattg gtgctaatat cattcttgac ccaattctga tgtttggatt acagcttggt
    10201 attcgtgggg cagccattgc tacagtaatc ggaaatgctt tcgctgttat ctattatatt
    10261 gtctgtatac aacgagcaga caatcagtta tctgctcttc caaaatattt caggcttgaa
    10321 aaacaaatgc taaaagaaat ttttttagtt ggattatctg caatgttgtt agatattctt
    10381 ttgattgttt caagccttat gtttaattac tatgcactaa aatatggaga ttatgtgctt
    10441 gccggatttg ggatttctca aaaacttgtg cagattgtcg acctaatcgg catgggactt
    10501 tacatgggag taattccact tattgctact gcctatggtg caagaaatga acttcgtgtg
    10561 aaagaaatca ttaaaaagac tgctctctat ttagcactag taattacatg tttgtttact
    10621 attctattta catgcagaaa ctttattgtt cattgttttt caaatgattc agatgtaatt
    10681 cgtataggtg cgtacatctt aaccgttcaa ctctgttctt ctttctttgc ggcaggagcg
    10741 ggtcttctaa cgggaatttt tcaggcaaaa ggagaaggaa ctccggctgt tgttatgtcc
    10801 gttatgagag gtattatgct cataccagca attatcttcg gcaattatct ctttaaaatg
    10861 aatggagtta ttttttctct gcttgtagcc gaagctattt catgcattac agggcttgta
    10921 ttatataaat tgaaaaagta atgctgaact ccatcagact tgttaacaaa gttagtgatg
    10981 gttataaaaa tcatcaacaa taaattaaga gatttctata gaatgagtat agattggtag
    11041 gagctggaaa aatatgattg ggcttaaaaa aagaaatata aaaaaatgtt gaaaactggt
    11101 gatagagctg gagatgtatc attagctgat attcgggcta atatagaagc cactattgat
    11161 gaagacatga acagtccagc cccagaggta caggcaaatt tcaaaaagta ttttggcaat
    11221 aaacgtccta caccagaaga atatatttac aagattacaa aaaaacaaaa gtttgattta
    11281 cgactatttg ttgcctgcgg agtatatcaa caaataagcg ttaaagaatc tgcacagaaa
    11341 aacagagaaa ataagaagcg aatcacttct tattctctct gctgttcaag ataccatcaa
    11401 tcgtaccttg aatgattttt aattcgtcat cactcaataa atcaagtgac gaatctatct
    11461 gacggctaac tgtgcttttt tccacattct tcgctggata gaaatactcg tcaacagata
    11521 tattgaacat ggtaactaaa tcatggaata aatgaaagct agggtgtttc ccgatatttt
    11581 caatatctgc gatatgacgt tctccgtaaa agactttatc gcctaaatca tttctggaaa
    11641 gccctgcttt ctctctggct tctctgattg caagtcctaa aggacgaaaa tcaaagctgt
    11701 gcgtatcttt cttttttctc atttttaatc acctagcatg agtttatact attttcacag
    11761 gtttgctctg ctcaaggagc aatttgtgat tctaagtaaa acaggcagcc ggcaccgaca
    11821 accgaattta ttcctttttt ttagtttatc atcagccctt gagcatgaat taaaaactca
    11881 tatatcagat gttttaaata cagtctattt gttattagtg cagataggct gttttcatat
    11941 tttcaaaaag tttttcaatt ctgcaacaaa tcacaccctg ctgtacagat gtagaacgga
    12001 ttttgcggac attcaaaata aaaaagaatg tggaggtaac agacaatggc aaagacgatt
    12061 tttgaggaac tgggcggcaa atatgagcgg caaggagatt atttaatacc gtgcttgact
    12121 gtacccgccg aagaagaaca gccgataggc acatggggac agcggcatct ggactatctg
    12181 aagcagtacc gaaaggttac atacaccaat cttctcacaa gcggcaggct caacacttac
    12241 cttgccgaca tcgacaggca ggcgcaggaa cgctttgaac ggctcataga gggcatgaaa
    12301 caggcgcagg gcataacaga acgcctaaag gaagaaaatg ccctagaatg gacaggaaga
    12361 atgaataaca taagggcgtg tgcgagggag attgtgaacg aagaaatcat ttttgcataa
    12421 gtagagaagg gcggcagagt gtaaaagctc tgctgtcact gttttaaatt aacaatctgt
    12481 tttcgttgca tatatgacat tttcaaataa atcgacagag agctgcccta tgctattgat
    12541 acaattcatt ggaaccccta tactatatgg tgtatagcta tttcccacaa aagtgagaaa
    12601 tctgctgatg tgaaaaaaat ctgaaaacaa actgaatgat acaatgtgaa agaggaattt
    12661 tgtatgaaga atgtatataa acttgaattt cattcgggaa gcaaagaaga attattgcct
    12721 gattttgaat ctgaatttcc gtatattgca tctaatgcag aacttgacaa atatattggg
    12781 cgttctgcgc cgtggcattg gcatagggca atagagcttt tttatatgga gagtggcaca
    12841 ttagaatatt acacgccgaa aaagaaattg tctttttcgg caggttctgg aggttttatc
    12901 aattcaaatg tccttcacat gactaaggct gtttctagga cagaaaaaaa tatacagcgg
    12961 ctgcatattt ttgacacagc tcttatttct ggaaactatg ggagtaaaat tgagaaaaag
    13021 tatgttatgc caattactgc aaatccccaa attgaaatat atgctttccg ccccgataat
    13081 tttatacacg cagatatatt ggatttgata aaacagactt ttaccttatg cgagaatgac
    13141 attggatatg agataaagat aagggaatcc ctgtcccgaa tatggctaaa gctttttgag
    13201 ctgttttctg cttcatttga tgggaaagga aaatatgata aaaatgacga aagacttaag
    13261 aagatgttaa tttacataca cgaacatttt gcggataaaa ttgcggtttc agaacttgcc
    13321 acagttgcat gtttaagtga aagggaatgt ttcaggctgt ttcaaagcta tttgcataca
    13381 acgcccacaa agtacatcca aagttaccgt ttacaagaag cttgtgaaat gctcataaat
    13441 gggcaggaca caattacaga cattggacat gcctgcgggt tagggaacag cagctatttt
    13501 agcaagattt tccgtgaata ccaaaactgc actcccatag aatatcggaa gaaatggcag
    13561 gatagtcata tcttatgtcc gaaataaaat agataaataa ataattctgc gttataatga
    13621 tatatagcac atattttgtt atatcatttt aaggagaacg ctatgtttta cgaagccaaa
    13681 gattttttgg aaaccgcaga taaggaaact ttgcatatta tttccaatgc aaggaaactt
    13741 acaagggaat actattttac ggattatgat aatacaaaaa gaaaaaatga gattttgaaa
    13801 gaattgttgg gagctgttgg gaaaaatgtt gccattgatg tcccgcttca ttgtgactat
    13861 ggaaaaaatg tatttcttgg tgatgatgtc gttataaata tgaattgtac atttgtggac
    13921 aataagccca tacggattgg cagtcgggta ttgatagcat ctaatgttca gttttataca
    13981 tcttcccatc ctgttttgcc acaggagcgt ttcgtttcgg actgggaaga aactgggaca
    14041 acatttttca gaacttatgc ccgttccatt gaaatacaag acaatgtatg gattggaggg
    14101 ggaagcatta ttttagctgg cgtaacaatc ggtgaaaaca gtgtggttgg agcaggaagt
    14161 gttgttaccc gttcaattcc cgcaaattgt gttgctgttg ggaatccgtg taaagttatt
    14221 cgctgtttta cagagaaaag aggaaaagca taatgaaata tcaacatatt gtttttgaca
    14281 ttgatgggac tcttatcaac acagagcatg caattttgca ctctttacaa gacacattag
    14341 aagaatgtat acatgaaaaa gtacctgtca agcaattgtt atttgtaatg ggaattacgg
    14401 gagaagatgc attaaggcag ttaaaaatca ataatattcc gttgtctttg aaactatggg
    14461 aagaaaacat aaaaaaatac agtaatacaa taactgttta tgatggaatc caagaattat
    14521 taaacagtct atcagaatgc gattgtaaaa ttgggattgt cacctcaaaa acaaaagcag
    14581 agtttaaaga tgattttgat aggtttgggc tgaaacatta ttttaagacg attatttgcg
    14641 ctgatgatac aacagggcat aaaccatcca ctgaaccttt gttaaagtat atagaaattt
    14701 ctggggcata caacgagcaa atattataca taggtgatag caaatatgac agcttatgtg
    14761 ctaaaaatgc agaagttgat tttgcattgg caatgtgggg aagccatacc agagagttgg
    14821 aagccgatta cttcattgaa actccaaacg atttactagg cgctataaaa taagcaggaa
    14881 tgataagaaa ataattgggc aaagaggtgg ttttttgaat atagaaaagt ggattttatg
    14941 ccccgtttgc ggtggcaaga cacgtaataa aattagagag gatactgttt taataaatta
    15001 tcctctttat tgtcccaaat gcagacagga aagtttgatt gtagcaaaaa atatgcaaat
    15061 cagtattgtc atagagccta atgctcatac atacaaagcg gttaattatt agaatgatat
    15121 taacttgcag acaaggagga cacatggata ataatgaaaa atggctgcaa tgggcagtag
    15181 aattacaaag tctggcacag gcaggaattt tctatggaaa ggacgttttt gataaagaac
    15241 gctatgaaag aattagagaa attgcagcag aaatgatttc ttataaatca gaaatttcaa
    15301 tggataaggt caaaaatcta ttttgtaacg aaattgggta tcaaacacct aaaattgact
    15361 gtcgtgctgc tgtttttcaa aataacaaaa ttttgcttgt gcaagagaaa aatggaacat
    15421 ggtcattgcc tggaggttgg gttgacgtta atgtttcagt gaaagaaaat gtgatgaaag
    15481 aagtaaaaga agaagctggt ttagatgtaa tggctgatat ggttattgcc gtacaggaca
    15541 gggaaaagca taatttacca gtttatgcct ataaggtgtg caaaatattt atattatgtt
    15601 cagtcatagg gggcgagttt aaatccaata tagaaaccat atcgagtaac tactttggga
    15661 tgaacgagtt gcctatcctt gcaacagaaa aaaataatga ggaacagata aagatgtgct
    15721 ttgaagcata tcagtctgaa aactggaaaa cattttttga ttagtatttt ttagaaagag
    15781 ccagacactt tagatgcaga gccaatgaac ttgtgaaata gaatcacagt ttattggctc
    15841 tatttcattt cataagattt taaggcaaac gcccaccaaa taaaaaaaac gaggttcggt
    15901 gggcggtatt gctatgcccg aaaagactta acagacactc tccagacctg ttttagagtt
    15961 tggagggatt tttttatgtt cttttttcgg gtagttattc atctgctcat gcaacgcaga
    16021 gtttacccat acatagcata tcggggaatg gcaggaagcc agtcaaaaaa gttcctgctt
    16081 atgcaacgct acttcacgcc ttgaaaccag aagtagaatc tccacctaac agaatatgta
    16141 tctcctataa ccgtagaagt cacagaactt ttgcggtttt tcttttgtcg ttttttatcg
    16201 gaatgtgccg cagggctagt tcttgtgttg gctgtcgttc gccgcctttt ccatctggat
    16261 tttaacaatt caaaaattca gatgggaggt acttacggtg aagtatgcac caagaaaagt
    16321 atatatcaag aaaaatggcg gttatatgga gttatcctat acggacttct gccgccgcag
    16381 gcaagccgac cagagttaca tggacaagct gtttatcccc gtgcagggct gtctgcttga
    16441 ggtagtgcgg gaacagtacg cagattttta caaggagaaa gagcggtggc gttatctgaa
    16501 aaagttggac acaaaccaca agctgctctc attagagggc tttacggaca gtgagggaaa
    16561 tgtgcttgac ttcgttattg atgaaacggt ggacgttgcg gaaaccgttg tccatgcggt
    16621 gatggtggac agtctgaaag ccgccctgtc tttattgtcg ggcagagagc aggcattgat
    16681 aaacgccatc ttctttgaag aactttccga gcgggaagtc gggttgcggt taggcgtgac
    16741 acagagcgtt gtgaacaagc gcaaatccaa aatccttgcg aagctgagga agataatcga
    16801 aaacaaaatt taaggcgttc agcccccttg ttttttcctt tgggaaaatg agggggcttt
    16861 tccctgcccc ctcaatcaat tctgattgga ggaaaaaaag aatggcatac aaccacggac
    16921 gggaggacag gaaatggcgc atctggaaag aagcggaaga aaagattttg cgagagtgcg
    16981 gcgttgatga agaaaccatt gagcaaatcc gcacagacga cagggcagat tttaattcca
    17041 acaggcggtt ttaccgatgg gcgagcgact tcggcgaata ccttgagggc atggcagaca
    17101 gggagaagca ggcggaggta aagtctgttt ctgatttact ggacgagatt gaggacgaaa
    17161 ccctgtacct tgctttagtt acggtagaca ggcgcacgtt acaaatcgtc ctgctgaaaa
    17221 tgcagggcta ttccactaag gagattgccc cgcttgtgca tttaacggca ggggctgtct
    17281 atgcgaggtt aaaccatctg cggaagaagc tgcggaaaat tttataagcg tctcatatat
    17341 cctgctttcc tatgggctat cgggtgggga gggaaaactc tctcctactt tttagcagga
    17401 ggaaagggaa tggcatacgg ggcaaagaca tacaagcttc gggaggaatc cacggaaagc
    17461 ggcgcaaggt attttatcag ctttaaggac gggcagaggg aacatcacga actggaagtg
    17521 tctgaacaat tattcattga atttcggcag atggaaagga ggaacaggaa ccttcagcaa
    17581 tggaaccagc ggcacaggga gtttaacgag gtgtgggacg aaacccttta cagacgtgcg
    17641 ttaagagtgc ctaaaacgct tgatgaaaga atgattgaaa aagaacgaaa tgaaatgttc
    17701 cttaaagcgg ttgcccggct gccagagata caaaggcggc gtttcctgct ctattacgag
    17761 tatgatttca atttttacca aatcggcgca atggagcatt gcacagcttc cgctgtccag
    17821 aaatctgttt cggttgcaag ggagaaagtt aaggcggaaa tgaggaagta tctccaatct
    17881 taacgattac tgcccgaaaa aaaaattcat ttttatcggc gtggggatgg cggcattaca
    17941 tactctcact tctttgtgtg ggagtaaatc tatttaagga ggtcacgcct atgtgcaaca
    18001 aaaccaaaga cactgcccga aaggaggaaa gccatgcaga agcttcagac agtcaatgcc
    18061 gacacgctcc tctatgagcc gcttgagaag ccgtcctttg tggtggacgg tctgataccc
    18121 acgggcttaa ccctgttctg cggctcacag aaaatcggca agagctggct tatgctaaag
    18181 ctctgcctat gcgtgtcgca gggaatcccc ttgtgggata tgccgacacg ggagggcgac
    18241 gtgctttacc tctgccttga ggacacgttc tgccgcatac aggacagatt gttccgcttg
    18301 acggacgaag caagcgggcg gctctacttt gcggtggcga gcgacaagct gtcagacggt
    18361 cttatcgtgc agttggagga ttatctgaaa gaataccccg acagcaggct cattgtgatt
    18421 gacaccttgc agaaagtccg caccgcatcc aaagacaatg cctatgcaag cgactacggg
    18481 gacatctccc ttatcaaaga ctttgccgac aggcactcat tagcggtcat tgtcgtacac
    18541 cacatccgaa agcagaacga cagcgacgtg ttcaacaaag tgtctggcac gacgggattg
    18601 acggggagtg cggacgcaac ctttgttctg gaacaggaaa gccgtgcgtc caatgccgca
    18661 aagctgtatg tgacgggcag ggacacgccc tatcaggagt tcacgctccg cttccgtgat
    18721 tgcagttggg aactggtgga acggaaagag caggaacagc ttgccaaaga agcgatacca
    18781 gatgttcttt ttcggctggt ggattttatg caggacaagg aggaatggac gggaacagca
    18841 acggagctgt tagccgctat gggggaaacg gaaaccgtcc ccacggtgat tacgaaatgg
    18901 ctcaatgaat accgcaccac gtttttaagc gaaaatcata tctgctacca gtacagccgc
    18961 aaaaaagacg gcaggcagat agccctcgca aggcagacgg gtgacagcgg tgacagtgat
    19021 gacagcggta ttgggatacc ccctgttact gtcattgaca cctaaagcca tgtaaagctg
    19081 gcggctctgc cctgcgggtg acagcggtga cggtgatgac ggcaatattg ggataccccc
    19141 gccgctgtca tccctacggg agaacacccc gtaaacgcaa gatgcaggcg tgggcattac
    19201 tcgccctttt cggctcgtaa agccacccct gcggtcagaa aaatctaccg attttcccga
    19261 ctgcgtttac agggtgtaac acactacact ttgccctgca aagagccgtg tgccagacgt
    19321 tccctctgga ctcccttaaa gcagggctta cgccctgccc atcctgcgcc ttgcggcttc
    19381 ggatggaaga atgtgcggtg acagtcggcg gctaagaggg ggtatcccaa aaacaccgtc
    19441 atcatcgtta taaccgtcac gcaccagaga aagacggcag gacggtgaca gtgacagcca
    19501 agaggggggt atcccaaaat cactgtcatc accgtcacca ctgtcaccca aaggacagtt
    19561 acccgccgaa gaaaggagga atcctgccat gccctatgca atcctgcgtt tccagaaacg
    19621 caaggcaggc ggcgttgcgg cttgcgaacg ccacaacgag cggaagaaag aagcctataa
    19681 aagcaatcca gatattgata tggaacgctc taaaaacaat taccatctca tagcaccgcc
    19741 aaagtacacc tataaaaaag agataaaccg aatggtagct gaagcaggat gcaggacgag
    19801 gaaagacagc gtgatgatgg tggaaacgct catcaccgca tcgccagaat ttatgaacca
    19861 gttaccgccc gaagaacaaa aagagtattt ccagacggct cttgacttta tttcggagcg
    19921 tgtgggaaag aaaaacatcc tctccgcagt cgtccacatg gacgagagga cgccccatat
    19981 gcacctatgc tttgtgccgc ttacgccaga caacaagctg tcagcgaaat ccattttagg
    20041 caaccaaaag agcctttccg agtggcagac cgcctaccat gagcggatgt tcgcaaggtg
    20101 gagcgaattg gaaagggggc aatcctcaat ggaaacgaag cggaaacaca tccccacatg
    20161 gctctataag ttgggcggca ggatggataa acagtatgaa gaaatcgtgt ctgccctctc
    20221 cgacatcaac gcctttaacg caggaaagaa aagggataag gcgttagaac tgctctccgc
    20281 atggcttcca gacgtggaga aattctcaaa ggaaatcagt aaacagagtg cttatattga
    20341 cagtttaaaa gagagaatcg ggcaggaatc cgactatgcg gggcgtatgc gtgatgagaa
    20401 gtacgagcag gaacgaaagg tacagaaagc caaccagagg atatttgagt tgcagaaaac
    20461 caatcagcag atggaacggt tattgaaaaa gataccgcca gaagtgttag aggaattgca
    20521 gaaaagcaat cggaatagag caagagaaag gtaggtagca gattgaagaa acaggatttt
    20581 aaggtattaa agaccgcaga tttatacccg tttcccgaca acccgtttca tgtggtggag
    20641 gatgaaatgc tgtcagagtt ggcggaaagc attaaggagt ttggcattgt aacgccgata
    20701 atcacacgcc cgaaagagga cgggaatgga tatgaaatca ttgcgggaca gcggcgtgtc
    20761 cgtgcttccg agcttgcagg gataaacaca atccccgctt ttgttctgcc cttagaccgt
    20821 gaccgagcca tcatcacact tgtagacagc aatctccaaa gagaaaatat cctgccatcg
    20881 gagcgggcat ttgcctacaa gatgaaatcc gaagccatga agcggcaggg tttccgaaca
    20941 gatttaacct cgtcacaagt tgggacgaag ttgcggacgg acgataaagt ggcacagggc
    21001 ttcggcgttg gcaggatgac cgtgcagaga tttatccgat taacggaact gataccgcct
    21061 attttgcaga tggtggacga ggggaaaatc gcccttacgc ctgcggtgga gctgtccttt
    21121 ttgaagaaag gcgagcagga aaacctattc gccacaatgg agagcgagga agcgacgccc
    21181 tcactctcac aggcacagcg gatgaaaagc ctaagccaga gcaggcggct taacatggac
    21241 gctatctttg cgattatgac ggaggaaaag ggaaaccaga aagaaaccgt gaaaatcggc
    21301 atggagcggt taaagaaata cttcccgaaa ggaacaacgc cgaagcagat ggaggacacc
    21361 atcatcaaac ttttggagcg tgaattgcag aggaaacggg gcagggacag ccgctaatct
    21421 tctcttttcg gagggtaaat acaaggaact ggacgtaaga aaggtcaagg caataagacc
    21481 agaaaggggc aggaaatgaa agaaatccag tatgagattg taaaggaaat tgccgtgttg
    21541 tctacgagcg aaagcggcta cacaaaggaa atcaatttaa tctcatggaa cgggaaagag
    21601 ccgaaatatg acatccgcag cttttccccc aaccgtgaga agtgcggaaa gggaatcacg
    21661 ttgaccgctg atgaagcggc ggctctcctt aaagcattgc aggaagaatt gaacagcggg
    21721 gattgattgt gtctgattgg cagggcggga gcatttttat atactcccct gccctgtctg
    21781 gaaaggaaga attgagtatg ggcgaggata agaaagcgaa caaaaagaga aagcgcattg
    21841 tggcaagaca gccagtgcag atgattgtca gccgtgaata tgtcggcaca cagaccgttg
    21901 ccgaagcgtt catcccgatt atctccgagg acatccgcag gaagattgcc gaaggtgaca
    21961 ccttcgacaa tgaggatata tccgcttaga atgtacgcaa tggaacatga aaacagttag
    22021 ggcagatacg gaggttttac agtatggcag gaatcaaaga agaaaagaaa atctattcag
    22081 tcggcattta ctgccgctta tctaaggatg atggcacgga aaacgagagt gcgagcattg
    22141 ccacacagaa atccatcctc acggattatg tgaaaaagca gggctggcat ctggcaaaaa
    22201 cgtatgtgga cgacggttac tctggtacaa atttccaaag accgagtttc cagaacatga
    22261 ttaaggacat tgaaaacggg ctgataaact gcgtgattac aaaggattta tcccgtctgg
    22321 ggaggaatta tcttgactgc ggactatatc tggaagtctt tttcccagaa aataatgtgc
    22381 ggtatatagc ggtcaatgat ggcgttgaca ccttaaataa atcggcgatg gacatcacgc
    22441 cgttccgcaa catcctaaac gaaatgtatt cagccgatgt gtcggtcaag ataaaatcgg
    22501 catatcgagc gaggtttcag cagggaaaat tcatggggac atatgcaccc tatggctata
    22561 tcaaagaccc cgccgaccac aaccatttgc tgatagatga taaggtggcg cacgttgtaa
    22621 gggagatatt cgaccttgca ttagcgggaa atggacttgc aaaaatccgc aagcacatca
    22681 acagtcagca tattttacgc cctgccgctt atgcggcgga gcagggggcg gcaggctatg
    22741 aacggtactt tgagggtaat gaggagaacc gctatatttg gagcgagaac agcgtgaggg
    22801 gcattttgag aagcccaata tatgcgggaa accttgcagg ctacaagcgg attgccgcca
    22861 acatgaaaag caagaaacgc ccctctaagc tgcccgaaga atgggaagtg atacccgaca
    22921 cccatgaggg gatagtcacg caggaggaat ttgatattgt ccaacagctt atgacgagcc
    22981 gcagacggga aaagaataag ggcggctttg agaatatttt ttcaggcgtt atcaaatgtg
    23041 cggactgcgg ctatgctctg cgggctatga gtgcaaacag gaggaaacgc cccgacatca
    23101 tcgactgcat acaatacacc tgtaataatt atggcaggta cggcaacgtc atgtgtaccg
    23161 cacacgccat tgaagcgagg gacttattca acgccgtcct tgcagacatc aaccgttttg
    23221 cggatatggc ggtgaatgac gagcgggcgg taagggcgat tgagaagcgg ctcacggaaa
    23281 cagaccagag caaggcaaag gcgatggaga aagaacgaaa gaagctgaat aaacgccttg
    23341 cggagcttga caggctgttt tcctctcttt atgaggataa ggtcatggag cgtatcaccg
    23401 agcggaattt cgagatgatg tcggggaaat accagaaaga acagcttgaa atcgaagcga
    23461 gattaaaaga ggtaacggaa actcttaacg aaagctatga gaaatcgcag ggaatccgtg
    23521 acttcctctc cttaatccgc aactatcaag gcttaaagga actggacgca acggttgtaa
    23581 atgcactgat agacaagata cttgtttcgg agcgtgagaa atcagcggac ggaacagtga
    23641 aacaggaaat caagatttat tataaattca tcggctttgt cggtgaatta catatcacac
    23701 ctacaaaacg gtggacagcg ttacccgcta aacactgtac ggtgtgcggc attgaatacg
    23761 tccccggctc tggcatatca aagtattgcc ctgcttgtgc caagaagata cagagggaga
    23821 agtcaaacga gagcaaacgc aggagcaggg agcagaaaag gatggcatgt attgaactgt
    23881 ccgcaaaaaa tgaccgactg atatggtgca gaaagaggga tacatacctt tcacttcata
    23941 gagaaagggg gtatgatttt gaaaccatca gacttccaaa agacgataca gtgtcagttg
    24001 gactgtaagc tcaaaaaggt tgtgaaaggc agtgtccgta actaccgcaa ggaattagcc
    24061 agatgacagg caaaggaagt acccttttgt gagcttccag aaattgttat tgagaaattg
    24121 attgtctggg atgattacga aagtgactat gcgacattcg atgtgtgcag tacggaaatc
    24181 cgtgtgcttg atgaagaact tgaaaaatac aggatatatc ggcatttacc aacttatgaa
    24241 aagataatca gaaatttagt gtatttttat aataaaaata taatgtttgt atacaaaaat
    24301 attaaagaca ttttagtaag ttttgtatat aagcaaacat gtatttttta atatagttat
    24361 ctaaatatta ttttatatac aataaaatag gactcctaaa aataaaaaat atatcataaa
    24421 tataaataag tagatatagg ttttaatttg atttataaac ctattataaa ataaaattca
    24481 tgatttttat aagcaataaa atttttagga ggatatatga tgaataaaag aatgaaacta
    24541 attccatatg aaataaatga aaatctaaga ggtgcaaaaa ataaattccc atatggaata
    24601 aaacaaatga atgctagggg aatgtgggat gaaggttata ctggtaaaaa tattgtagtt
    24661 ggtataatag atacaggttg tgatatatct catcctcttt taaaaggaaa aataattggt
    24721 ggtgcaaatt ttagtgatga cagtaatgga aataaaaata tatatgagga ttttaatggt
    24781 catggaactc atgtggcggg tattatagct gcatctaatt ataataatga agttatggga
    24841 gtagctccag attgtaaatt attaatagca aaagcattaa ataaagatgg taccggaaca
    24901 tatcaaagta taattaatgc tattaacttt gctgtaaata acaaggttga tattatatct
    24961 atgtctcttg ggggaaacaa agatgataag aatttaaaaa atgctgtcat gcaagcagta
    25021 aaaaataata tttctgtagt gtgtgcagca ggtaataatg gagatggtga ttctagtaca
    25081 agtgagtata gttatccagc cagttatgct gaggtaatag aagtaggtgc aataaatgaa
    25141 aactatttgg ttgaaaagtt tagtaattca aatactacaa tagatttggt ggctccagga
    25201 agaaatatta tatcgactta tatggataat aaacttgcta ttatgagtgg tactagtatg
    25261 agtgcaccat acgtatcagg ctcattagca ctaattaaag aatgggcaag agaggagttt
    25321 gaaagagatt tagatgaagc tgaactgtat gcacaattaa taaaatgtac gagagcgctt
    25381 ggaataccta gaacggaaca aggaaatgga tacttatatt taaatcttta taaatacaag
    25441 aataatagca aaagataatt tttgatttga tgataaaata gctatattat atagagtcga
    25501 gacaaataat aaaaattact taggtgtaag attttacatc aatgtataaa ggtattaagt
    25561 gataaaattt ataaacatat tagctagtta gaattgaaaa ataaatatac gatattatag
    25621 atagcacatc tggaaaaggt gtgtttttct atgtacttat acatataaaa gatttataag
    25681 agatgcaaaa gtactataag ttagaaattt ttctatgaaa gattagaaat acgatacagt
    25741 gttttgatat tataaaatga atataaagta taaatgataa atgttatcaa taagtattga
    25801 atttcaaaat caattgtgat attctatatt tagaaaaata aagagatttc agataaagaa
    25861 atcttttgtt ttttagatgt tagttagcta taactaacta ttgattaatt aaaaaatact
    25921 acaggaggta aaaatgagta aaatatatat tgtttattgg agtggaacag gaaatactga
    25981 aaaaatggca aattttgtgg ctgaaggtgt gaagttaaaa ggtaagacac cagaagtttt
    26041 agatgtgagc ttactgaaac caagtgattt aaaagaagaa gataaatttg cattaggttg
    26101 cccatctatg ggagcagagc aactagaaga gggggatatg gagccatttg tttcagaatt
    26161 agaatctatg gtatcaggta aacagattgg attatttggt tcatatggat ggggaaattg
    26221 tgaatggatg agagattggg aagaacgtat gcaaaatgct ggtgctacaa ttattggtgg
    26281 agaaggaatt acagcaatgg aagacccaaa tgaagaagca aaagatgagt gtatagaatt
    26341 aggcaaaacg ttagctgaat aaatttgtat attataaaaa tagtataaat agcaactaat
    26401 gatgatagca gtatataata ataagagaga ctaatattat gatacataag aaaatatcct
    26461 taatagagat agataaaata ttagtctctt ttaatataaa attagattta taatttaatg
    26521 ttgtttttga attggtacaa tctcattata aaaagataat aattgattga taacataagt
    26581 gataaaggta gtatcttgtg ccaaacaaag catatttgct ccaatattaa cccattcttc
    26641 aatacttttc ttttctattg taggaaaaat aataaagggc atcttatatt ttttgcatat
    26701 ttcagcagca tgagaaatca tatctttaaa acgccgccat tggagacaat gagcggcgtt
    26761 ttggtgtaat ggctaaggag aggagggata ggaatgaata tccgaggggc aaacagggca
    26821 ggtgtggcca tacctgcctt gcttacagat ataatcaaag ccggtaaaga ttgcaaattt
    26881 accaagggtt ccatctaggg gaaagtcgca ttagtctaat taatacctgt ctaaccacca
    26941 aaccttattg ttttgccata aacataatgt tgcttgacag aagcaggaat agcttatata
    27001 ataaaaacca acagtcggtt tttaataaga aggagttata taatgactag aaagaacaat
    27061 ccaaagcaag ctattgaaaa tatcattacc atttctgcaa agttgtttgc tgaaaaagga
    27121 tacgacaaaa caagtatgca aaatattgtt gatgcttcgg gaatgtcaaa gggcggaatt
    27181 tttcatcact tcagttcaaa agaagatatt tttaatgtgg tcatggaaag gcgctttgaa
    27241 cagataatag agacagtaaa tcaatggctc ggtgaaatgc atggacttac agcaaaagag
    27301 aagcttagaa gtttagttag gcggcattta acggatgagg tgataaaaga atctagtaac
    27361 atgattacaa gcgcgataga aagtccgcat atcatactgg catttacaca ggataatttg
    27421 aaaaaactag caccaatatt agcaaatgtt ttacgagaag gcatagagga tagaagcatc
    27481 atcacagagt tcccagatga atgcgcagag gtaattttgc tgctctttaa cttttggtgt
    27541 gatacagatg tatttcaggg ggactttcct acaattcgta aacggtttca attcttacag
    27601 tttcttatga gacaaatagg agttgatatc ctggaagatg agattataga atcaattaat
    27661 attttttatg aaaggaaacc aatgggacag gtagagtaac aaaactaaaa tagcaacata
    27721 ctttttttaa tgttagagga gatatctatg gctaaaaaaa ttcatgaaag aaggtactta
    27781 aaatgatatt aatcacactt tgcatactag ttgctgtttt tgttctggcg tttgccggtt
    27841 tgcgtctgat agcccccacg attatacgta caagccataa aatagaagct cctggaatcg
    27901 accgcatgga aatggtggag atcggcggca tacagcaggc gttatatatc cggggacaaa
    27961 acgcagacaa ccccatcatc ctttgggttc atgggggtcc tggtaattca atgatgccat
    28021 ttttacatct gtaccagtat gagtgggaaa atgattttac tgtggtgaac tgggatcagc
    28081 gaaacgtagg caaaacatac tttgcgaacg atccggcagc agttttgcag accatgagcg
    28141 cggagcgtgt tctgcaagac gtccatgagg tgacagcata tttgaagcaa caattcaaca
    28201 aggagaaaat tatccttata ggtcatagct ggggaacggt gctgggaact atggctgtgc
    28261 aaacctatcc ggaggattac agcgcgtaca ttgggattgc gcagaccgtt aatatggtgg
    28321 acaatgagcg cgtgggctat gaaaagacac ttgaaatggt gaaagctgca ggaaagcaaa
    28381 aagatatcaa ggcgctggaa gctgttgcac catatccgcc agcaaaatat ggtccaagct
    28441 atttggcggc tcttatgaca gtaagaacat accaaagcaa gtatgggctt tctataaata
    28501 tggatttggg caatataatc agtatactgg caaccccgta ttattcattg agcgagttaa
    28561 aaaatacaac cattgtcaat ccaaatgcga ttgacaatca aggtgatgta ttgcggtttt
    28621 tagtggaaga agctgacata agaaattatg gagttgacta tcaggttcct gtatactaca
    28681 tcatgggaga aaatgactat aatagcccct atcttccagc gaagaaattt tttgatgaaa
    28741 tagtggcgcc agacaaacag atttttttta taccagatgc agaccatctg ccatttctta
    28801 gcaaaaaggc agaatttgac tgcatattgt tagaggaaat cgctccaaag ttagcaaagt
    28861 aacaactagg acagtaacgt ggatatggtg gcaatttctt ttactattcc agaacgcttc
    28921 agtttgtttc cagcaactgg tttcaatgag gtgcttgaga tatatctatt tagagggttt
    28981 taagagagga ctatcactta tggacatttt gtccataagt gacagggtca gcaatcggaa
    29041 agggtggtca tgctatgagt gaactgagac ctttatatca gacagttaaa aaccatggag
    29101 tgattatgaa accataagat gattcttgta atgtacagga gtcatctttt atatttattt
    29161 tcttttttag atttaattct ctacttgatt tagatacaag agaggcttcg ccttgtttta
    29221 agtatatttt tctacttata ccattatttc ttttttattt gcttttccac tttaaataat
    29281 acaacttcaa cacaatttga agctaatatc ttttattgac tattgtataa agtattttta
    29341 taatgttctt attcatataa aattttattc cacttactat tgaattttat taagaaaaag
    29401 atttattact ttctatatga tagaaaaata agtggtatta gttatttcta ggaagagaat
    29461 atagagtatc ctatatttat tacaagatta aaaaaagcag gtttatatat tgaagatata
    29521 agaatgcttt catttttgtg atataagaaa caatatgttt gtgatataag agacaatatg
    29581 atagataaaa gaatttaatt atttcagcaa tataagcaag atattaaaat aaaatcatga
    29641 actagaagag tgtatataca aaatagctga gaagatagac tatttaagca aaaaaggtat
    29701 gtaaaaaata atttttctaa aagaatccaa cagtttttta tttctataag aaaaataata
    29761 ttaattggaa caatttaata atattctttc ttagatgtat ttctatatag tattggacaa
    29821 tgttatatac agttatttat atatgcaata aaaaggaaaa ttatgataac atatattgat
    29881 gtaagcagta aaaatacttt catttataga tataattatt ttgggaaaac actgatttta
    29941 caaaataaaa aagtaattat agaatttatc aatatattaa aaaactgaat tgtagtaaac
    30001 taagtgcaac taaaattaca ggagtattaa aagagtatga tgattttata gtaatgaaag
    30061 ttaatgatga tgatattatt ttaatataag aagggaagaa aaaatattta gacaaaaact
    30121 acgaggtgag tttatggtgg attttattga gtcaaataat gaagtacaaa aatttgattg
    30181 gggagaggtt atgtggatac acgaaccatc aaaaacacaa ttcaatagac ttagtgctgg
    30241 aattgtaaga ttttttccgg gaaactgcca agaaaagcat tttcatttaa gtgaagaaca
    30301 gcttttatat gtgattcagg gagaaggaat acaaataatt gatggtaaaa aggtcaatat
    30361 aaaggaaaca tctatagttt attgcccacc atattcagaa catgaaatta taaacactgg
    30421 taaaattgat ttagtaatat taattactta tgttcctcat aaattttcga gtttgagaca
    30481 aatacctata gtattttctg aaaacaatat acaggagtta gttaatgtaa acataattga
    30541 aaatcttgca aatcaaatat ctaatatatt gaagcttaga atatctgtat atgacttaaa
    30601 gtataaagaa atatttgaga ctaagaaaga aaataaattt tgcgatattt gtaaaaatat
    30661 aaaaccgtgt actaaaaaac ttgttaaaag cataaataat gataactttg aaaaagtgta
    30721 tcattgtgag tatggtgttt ccagtttaga gatacctata gtattagaag aaaatatagt
    30781 tggatatata gaatgtggta attttatagt atataagtct atttatatag ataaaaattt
    30841 atctgaatta tcaagtagtt ctggtattga tataaaatac ataaacaaaa tttacaatga
    30901 atttccatta aatcctaaaa gtagattata tgtattaaaa gaaaatttat taatgatgtc
    30961 tgaatttatt caggaaatag ctaagaggaa tttttttgaa aatcaactta gtataaaaga
    31021 tgaggagata ttgaagagta gaaaagaaaa tataagactt gaagaggcac ttaaaaaagc
    31081 aaatagtaga ttattagaag aagagtatat tattaatccg atagatatgt tcaataattc
    31141 ttcaaaagaa tatccctttg aattagaact ttatattgaa aaagaaatta aaaatatgaa
    31201 tttagaaggt gtttataatc taatagatac aaacaaatta agatataatg atgttagaga
    31261 tactattcag gaaatgatat ttgtattgtc tagaacagtg cttagagatt tagaggattt
    31321 aaaacttata tcttatttaa gaaataaata taataaaaaa atatcacttg taaacagtga
    31381 tgaagattta tggaatgtat tatttgaatt ttccaaagag tgtattgata agaatagagc
    31441 attttggaga aaagataaag gaaatctaat tgaaaatata aacgaatata taaaaaaata
    31501 ttataaagaa aatataaatt tgaatagtat atcagatgtt ttttttataa gtccaaatta
    31561 tttgagttct atttttaatg aaagaaataa agtttcaata actgagtata taaatcttct
    31621 taggatagaa gaatctaaaa aatatctgtt agatagaagc atgagtatta gtgatatttg
    31681 taagaaagta ggttttaata acagtagtta tttttcacaa atatttaaga agtttaatag
    31741 tataactcca aatgaatata gaaagaatat gctggataat aagtattaaa taagattata
    31801 taatatatat tgtaagaaaa attgaaagag aatgatggag gaattttatg ttttcagtta
    31861 tttttttatg tatagggggg tttttagctg cttttgtaga ttctatagca ggaggaggag
    31921 gacttataag catgcctgtt cttatggcaa ttggagtgcc agtacatctt gccattggta
    31981 caaataaatt tgcagcatca gcaggatgta taagtagtgc ctatagatat gcaaagtctg
    32041 gaaaaattaa taacaacctt ttaaaaaaat tagtaccatt tactattatt ggtagtgttc
    32101 taggtgtgag atgtgtatta tcaataagtg aagagatatt aaatgttttg gttgtggtta
    32161 tgattttaat agtggctatt tacaccttta tttctaaaaa tttaggtcaa gaagataatt
    32221 ttgaagctgt taataagaaa aatttaagac tagggatgct tatggctctt ataatgggtt
    32281 tttatgatgg tttttttggt ccaggtacag gaactttttt gacttttgga tttataaaaa
    32341 tatatggata tgatttttta catgcttctg caaatacaaa aatattaaac ttaacaagta
    32401 atataacttc attgttatta ttcatgataa atggtcaagt agattataaa attgctatag
    32461 tgtttgcatt agtgatgata atgggagctt atgtaggtgc taaagttgct ataaagaaag
    32521 gttcaaagat gataaaacca atatttttag taatggcatt atttatggtc gtaaaattgg
    32581 tatatcaaac attagtttag cttatagact ttttaaattt ataagtaatt gtaaagcttt
    32641 tatatttaat ctaatcatat agctttataa aaattctaat tatcttctaa tatagttcat
    32701 atataataca catataaact gtaatcttac aatagaagga ttatatatca taaaaatata
    32761 accttgattt atatatatga aatatatggt aatttgtagg aggaatgttt atgaacatat
    32821 caagaagagc tatgaagata attgaactgg cacaaaaaat tgctaataaa agaggtgtaa
    32881 cagtacaaga cgcttggaat gatgcgatga aagaatataa agaaaaatat gaatatgttg
    32941 cataagatat gcgttatatt ttaaatataa gaaaatataa aacaaaaaag attgtctcaa
    33001 aataagattg tactgagact caaaagttag attttataca ggaatggaat tttcattcct
    33061 gtatttttaa ttttacataa ctttaaattc atattcaaat ctatatttaa caaggttatg
    33121 ctaaattaat tttttttatt cttttgttat tataataata aatatattct gttatagttg
    33181 tatctaatta gtagatgttt ttatgtactt ttatacagta tatttctcgt ttcattcttt
    33241 tctatttaaa taggacttaa ctacttttta aattgggttt agctactttt aatttaaaat
    33301 taaaagtatt gttatatata taagtacctc aatcattagg tttttgcttt aacaattatg
    33361 gtgcaataca cttttgttaa gttaaaaaaa ttagataaag taagattaaa taaaagcgac
    33421 ttaagtaaat tgagaatctt aatataaaaa ttttcaataa atatttagaa ataactattt
    33481 agaaaaattt ctaaatagct attgaaataa aatggatgtt atgttatatt ctatttagat
    33541 gaaattctaa atagcgaggt gatggtgttg gggtttccag aaacattcaa agctctttca
    33601 gaccctataa gaagagaaat attggttatg ttgagggaga ataaaatgtc agcaggagaa
    33661 attagtgaaa aatttaatat gacgaatgct acaatttctt atcatctatc tcaactaaaa
    33721 aaggcaggac tcatatttga aacaaagtat aagaacttta ttttctacga aataaatatt
    33781 tcagttttcg aagaggtcat gctttggttt tcacaattta tggagaaggg agaaaaagat
    33841 aatgaaaaaa gcgataaata aacaatttat tttatctact ttaatatgtt ttataccatt
    33901 tattgtatca atatattttt ataatagatt accaaatgaa gttgcaattc attttgataa
    33961 ttatggaaat ccagataatt atgctccaaa ggttatagca gcttttggtg taccattgtt
    34021 aatgctatgt atccatttgt atacatggtt tagacttgag aatgagccta agaaagctaa
    34081 tttttcaaat gttatacaaa atttatcaaa atggggagtt gctatacttt cagtaattat
    34141 acaaataatg atggttttat attcaacagg agttagtttg gagtctaatt tttatacagg
    34201 attaatttta ggaataatag ttattttatt tggaaactat cttcctaaat gtaaacgaaa
    34261 ttactcagta ggaataattt taccatggac tcttaatgat gaagataatt ggaataagac
    34321 acaccattta gctggatgga tttggcttat tggtggaata ttattaatta ttaatgcatt
    34381 tattaatatt cctttttata atatctttgt aatctttgta attgtaatac taccatttat
    34441 atattcttat ttgatgtata aaatttcagg taaaaataac taatataatt aatcactata
    34501 ataatgtttg gataagaata atatatttca gaactgagat agataataaa gaaattacta
    34561 agatttctat tttagttctg aaaaaatctt acttatatga taacttattg agatttcaaa
    34621 aaataatata aattaggcta atgaacataa aatgaaaatt tgtatttaat attgaaaata
    34681 taagtacggt gtgatattct tataagaaaa acataggagg tagaagatga atactagaga
    34741 aatgaaagaa tatagggtat tttacaataa aaaattaagc gaaacagatg agttttttag
    34801 agtatttgga agtcttgatg ataagactta ttcagaaggg gctataagta aaaaaaataa
    34861 ggaattaatg ggactagcta tttcaatttt aagccgatgt gatgagtgta tttgttatca
    34921 tattgagggt tgtattaatt ctggagcaag taaagatgaa attatagaag ctataaaaat
    34981 aggtgtaatt ggtggcgggt ctattacata tccaaacgca agatttgcaa taaaaatttt
    35041 agaagaattt aatatataat tttgatagac gtagtttatt tagactaata ataatagtct
    35101 atttaagtct ttgaaattaa gctttatttt ctaagttcac ttcttattaa gtttttagaa
    35161 ttgcatatat aaatataaat ttttaaataa tatagcagtt ttaaattatt tacatcatag
    35221 attgtattga gaatagtata ttgtcattat taaatctttt atacattttt tattttaaat
    35281 aaattaatat taaggtgatt atatttacat atttgtattt ttatgaacta gaatattctt
    35341 tataaattca tagcagtttt aatagataac tttttcagat agattaaaca aagttttatt
    35401 tactgtattc tattatcagt ttcctacaaa ttaaattgtc tatttttatt tatagagtag
    35461 aataaactgt ttttgttaag aattttgaag gtaaagctag tttaaaaaaa taaagggact
    35521 aatttgtcta acgtttattg gtgaaaaata agtctataga agttataata aatatataaa
    35581 aatgtatgag aggtgttata tgtttggtaa accaaaagaa agtgttagat ttttagactt
    35641 taatgatgta gcagaaaagt ttggagagaa aaaggctgtt gcaatttttg atgccatagc
    35701 tggaaaaaaa
//
LOCUS       DAFAZV010000045        34485 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFAZV010000045 DAFAZV010000000
VERSION     DAFAZV010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 34485)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34485)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34485
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.045"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(413..2800)
                     /gene="cadA"
                     /locus_tag="KOU88_002962"
     CDS             complement(413..2800)
                     /gene="cadA"
                     /locus_tag="KOU88_002962"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBK3212820.1"
                     /translation="MEANNSIKKEFILGGLNCAHCAEEINNKVSKLQEVKSSNLNFIN
                     KKLTVNIKESFNEDTTIEKIIDIIDSTEPGLDIQISSKENAASKTSIKKELILGGLNC
                     AHCAEEINNKVSKLKEVESSNLNFVNKKLTVNISNNFEEDDVINKIKEIINSTEPGLD
                     IQVGSTDKVKGRTTEKSGAVNDTNKKELIPLIIGALVYIFGIYQTATGYESQFSNIVF
                     IVAYVIVGGDVLLRAIRNISKGRVFDENFLMALATVGALTIGELSEAVGVMLFYKVGE
                     YLQGVAVGKSRKSITSLMQIRPDYANLKVNSEVKVVSPEEVNVGDIIVVKPGEKVPLD
                     GVVVDGVSMLDTSALTGESVLREVEKGDEILSGVINKNALLSIEVTKSFGESTVSKIL
                     DLVENSSIKKSKTENFISKFSRYYTPIVVIAALLIAFVPPLVISGEVFSDWLYRGLIF
                     LVVSCPCALVLSIPLSFFSGIGFASKNGILIKGSNYLEALRSVDTVVFDKTGTLTKGV
                     FNVTKLNPEGISEEELLEYAAIAEVNSNHPIAKSILSYYNKKIDLDTIDSYEEIAAYG
                     IRVKHNGNFILAGNEKLMKKENISYSSAKEVGTVVYIAVDKVYRGYIVISDEVKEDSK
                     NAIRSLKEIGVKEVVMLTGDNEKVAKNIAQELELDTVYSNLLPNEKVDRLEDLYEGRT
                     EKEKIAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVLMTDEPSKISKAIEIA
                     NKTNKIVWQNIIFALGVKIIVMILGAGGVATMWEAIFADVGVALIAVVNAMRAMR"
     gene            complement(2823..3188)
                     /locus_tag="KOU88_002963"
     CDS             complement(2823..3188)
                     /locus_tag="KOU88_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212821.1"
                     /translation="MREEINDCNCNIVHEEIVTEAKSTMPDEEMLYDLAELFKVFGDT
                     TRVKILYALFANEMCVCDIASLLNMTHSAISHQLRVLKQARLVKFRREGKTVYYSLDD
                     SHISQIFDCGLNHIRETYK"
     gene            3387..4235
                     /locus_tag="KOU88_002964"
     CDS             3387..4235
                     /locus_tag="KOU88_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212822.1"
                     /translation="MSNKKKKDLDTSYMPYLDPANYADYITNEEIPQDELRNDPQISN
                     GYTKIPNNQNINNLYPNNVNHYPKSSNSPNNLPNTNNTSGNMNYNTSATNNMPNNMNN
                     NTGMPNNMSNNMNSNMGMPNNMPNNMNSNMGMPNNMPNNMNSNMGMPNNVPNNMNSNM
                     GMPNNMSNNMNSNMGMPNNMSGNMNNNMYGNTGMPNNMNSNMGYNMNNTMGIPNFSCN
                     QNMPPNVLMMIPGVICHNTMQGMPVVMPSTMPPNIYPTPYGSSNMSVQGIPQATNIEE
                     FDEEEM"
     gene            complement(4672..5760)
                     /locus_tag="KOU88_002965"
     CDS             complement(4672..5760)
                     /locus_tag="KOU88_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212823.1"
                     /translation="MNFNFAKATNSRLMGSLGLIINWIDDENNHFCQYFLLDAEGLGL
                     ADYVSLNNPTQEEAYMEEERLMGGFGSDRVELTKDESLFLVSYFGNKNLYYDKLLPGD
                     KCEYIDIIKNYKTDLTIEKLYNKICKRVDEEVEFINYMTMRFIAWDRESLKYFSGSDE
                     IANMHITNINGTLLKNVVSDKGQGRYISEALYEDNDGYYICKIAFCISKCYETGFRIN
                     SLLVTDKEPMYDFEVFDEISKSEFVSVYSVNSPEEFAGVFYRENPFLLKSNMNEGIFF
                     TRFNFNNDHVKENVYIINNDMKAIYYLMGNKFFIGTYNENDCNYINEISQSNYSDYIK
                     FEEKFFFEQNALYDFAESGSLDFDDFLE"
     gene            5885..6613
                     /locus_tag="KOU88_002966"
     CDS             5885..6613
                     /locus_tag="KOU88_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBK3212824.1"
                     /translation="MKNIAAFFDIDGTLYRDSLMVEHFKKLIKYDIIDQKNWYKHARD
                     TFMDWDKRQGNYDDYLLEICDLYVDSLKGLDKTCINFTSDQVIKLKADRVYKYTRSRI
                     EWHLNQGHIVIFISGSPGFLVEKMAKKYNVTDFLGSDYVFENNIFTGTVIPMWDSISK
                     NNAINDFVVKYDLDLSNSYAYGDTNGDINMLKRVGNPIAINPTKELLSQISLDEEISK
                     NVEIIVERKDIIYSLSTDVNIVDI"
     gene            complement(6815..7306)
                     /locus_tag="KOU88_002967"
     CDS             complement(6815..7306)
                     /locus_tag="KOU88_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212825.1"
                     /translation="MSIKVAYGGVLLALNVILLTLTNIIPVNTLFIMGLASLLVSIVI
                     MEWGFKSGIAFYIGSIVLGFIVMASKSQWIVYSLTFGIYGIVKYLIEKDRSIYIEYFM
                     KLVFANIMILILYFLLRTIVYIPINIFIIGSFEIAFIVYDYVYSSFIGYYNNRLRKML
                     FKK"
     gene            complement(7317..7760)
                     /locus_tag="KOU88_002968"
     CDS             complement(7317..7760)
                     /locus_tag="KOU88_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212826.1"
                     /translation="MYSNTYNNENFMRARSFIENSEFKKAYDFLKTLTDKCAEWYYLT
                     GFSAMNIGYYEEGEDFLKRAKFMEPENSEYSDALRSYTQYRNDYSNRADNYNRRRRND
                     LDGCCCCCCDDCCCCLGDDCCENCAKLWCLDSCCECFGGDLITCC"
     gene            complement(7750..8589)
                     /locus_tag="KOU88_002969"
     CDS             complement(7750..8589)
                     /locus_tag="KOU88_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212827.1"
                     /translation="MFGYVKINKMDLTFREYDYYKAYYCGLCKYLKRNHGEISRFSLN
                     YDITFLIVLLTAVYNPESISTEEVCIVNPFKKKKVITNDITEYAASMNILLTYYKLED
                     NLMDDKRIKDKLAYYIYKNKLKLAYEKYPEKAEYIKQQLNELNKLEKDKNINIDEVSS
                     IFGNIMGEVFVYKKDENERNLRMIGFNIGKYIYLLDAYEDLDEDFKKGRYNPFIEYID
                     KNDELKEKVKKIIVTSLGFLARGIDNLNLNKNVGIIENIIYSGVYLRYINILESRGGK
                     NVQ"
     gene            complement(8808..10193)
                     /locus_tag="KOU88_002970"
     CDS             complement(8808..10193)
                     /locus_tag="KOU88_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3212828.1"
                     /translation="MDNLNKKFLMEYIDEIQGELRDISDKIWKNPELQYKEYYASNLQ
                     KECLKKHGFSIEGLEGMDTAFVASYGEGRPVIAVLGEYDALDGLSQKVSTTKEPIVDG
                     GAGHGCGHNLLGTGSIGAVIAVKELIKLKKLKGTIKYYGCPAEEDLSGKVLMIKKGFF
                     DGIDCAFSWHPFDINTPIRIPTLANYSVKFRYNGISAHAAQAPYNGRSALDAVELMNI
                     GCNYLREHIFDNCRVHYVTTNGGKMPNIVPDFAEVWYYIRGVKMEHVRDVFGRIVDIA
                     KGAALMTGTIMEYDIISGVYDYIPNTILTDILSQNMKLVGVQNYNEDDYYFADKLAET
                     VSIDKRSSVSSVLSGNKDITKMNLHDEVTDDTFTHNNCISLSLDIGDVSYIIPTAQCS
                     CSVWPIGISAHTWQSCASAGSDMGFKAMLLASKSISCSINDVMLDELVINKAKKELKD
                     TVGSFKYIPII"
     gene            complement(10366..11109)
                     /locus_tag="KOU88_002971"
     CDS             complement(10366..11109)
                     /locus_tag="KOU88_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBK3212829.1"
                     /translation="MKKVLIVGESWVKNITHIKGFDTFVTTHYEEAVKWLKEAIESGG
                     YETVHMPAHVAADSFPYKLEELNEYDCIILSDIGSNTFLLSNSTFIDCNSNPDRLELI
                     KEYVNNGGALIMVGGYMSFTGIDAKARFGETAIKDVLPITMIDKDDRVEKPAGIIPEV
                     IDSEHPVLKGIPTEWPKFLGYNKTVARDNCPVLATIGGDPFVAVGEFGKGKSAIFSSD
                     CAPHWGPKEFTDWKYYNKLWVNMLDWLTC"
     gene            complement(11129..12391)
                     /locus_tag="KOU88_002972"
     CDS             complement(11129..12391)
                     /locus_tag="KOU88_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK3212830.1"
                     /translation="MKKILLDTLNSKKQEYIDYLKELVSIKTEDVGHGILGGFEKEGQ
                     EYIEKLANYIGFSVDRQEMSEELIKKAKNIYKEGNLGHNYQDRYNLICKYSDDLPGKT
                     IVFNGHVDTMPPGDISKWKYNPYRATEDNGKLYGLGTADMKSGLIASILAVKLIKDSG
                     LNVPGNVKIMSVVDEEGGGNGTINAVMNGIDGDCCIICEPSEQNLIVAHMGFVFFEVE
                     VKGVSLHCGSKWEGVNAIEKAMLLLQDIKELEHNWLMIYKHPLLPSPTINLGVINGGT
                     AGSTVPDKCVFNLCVHFLPNIMSYEQVVNDVTNVIMTRANGDLWLKDNKPNINIYQSG
                     LGFEMDKDSDFVVNAHKILEETLGKKLEIKGSTAGNDARVMKNLAEIPTLILGPGSIE
                     QCHSIDEYVEIKEYLDSILMYASLILNL"
     gene            complement(12575..13573)
                     /locus_tag="KOU88_002973"
     CDS             complement(12575..13573)
                     /locus_tag="KOU88_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBK3212831.1"
                     /translation="MSSITKHKEEKSSPLLTKLTSVFRDQGSAAVGLVIIFIIMSVAS
                     SNFLTLDNLINVGRQISINAILAVGMTFVIITGGIDLSVGAVIALVGTFWATTVVNYN
                     APIWVGMILALAIGTILGVIKGAIISTQKLPPFIVTLAMLTIISGASFVFTGGRPISV
                     NTDAFKMLGRGYIGPIPIPVIIMIIVVIAGHFLLKRTNFGRHVHAVGGNEEAARLCGV
                     KVNKVIVKVYALAGLLTALAGIILSSRLASGSPTVGDGAELDAIAAVVLGGTNMMGGS
                     GSIVGTCIGVGIIGILGNGLNLLSVSSYNQMIIKGLVMLFAIWINNIKLKKSAKSK"
     gene            complement(13557..15068)
                     /locus_tag="KOU88_002974"
     CDS             complement(13557..15068)
                     /locus_tag="KOU88_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBK3212832.1"
                     /translation="MSNIILKLSNIAKEFPGVRALDNVNFELFHGEVHALLGENGAGK
                     STMIKILTGAHSKTSGKFIFEGKEIENISPDISKKIGINAIYQELTVFDELTVAQNIF
                     MGKEINGKVLTNDKKMNEEAKKIFDNMGIDINPNSLVKELSIAQKQMVEIARVLSSET
                     KVLIMDEPTSSISKKETEILFRLINDLKESGVSIIYISHRMEELFEICDRITIMRDGK
                     TISTLNTKDVSSEEELVNLMIDRKLDQFFPKRKVEIKEEIMRVENLTKNNVFNDISFN
                     IRKGEILGIGGLVGSKRSEIVEAIFGLRTYDSGKIYLNNEEVKFKTPSDAIENGLGLI
                     TEDRKGTGLFLQMSVKENTTMAGLKKISKFKSIIDRKKEKEILEKYIEALKIKTPHMN
                     QVIQSLSGGNQQKAIIARWLLLQPDILIMDEPTRGIDVNAKAEIYNLMGDLVESGVSI
                     IMISSEIPELISMSDRIMVMREGHISGFLEGEEMVENNVLKLAFGGKINEFNN"
     gene            complement(15122..16084)
                     /locus_tag="KOU88_002975"
     CDS             complement(15122..16084)
                     /locus_tag="KOU88_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBK3212833.1"
                     /translation="MRVRKILSLGIAGILAIGMLTGCSMEGPSKSDNKGGSDKKDLTI
                     GVSTITLQHQFFIDIDEGIKEKAKELGVKVIVNDPDQDVAKQTSAIEDFIQQNVDGMI
                     VLGTDNSAIVPAVEGAFEKMPVVTVDAVLNTENITSYVGTVSYDAGKKLGEYTKKYID
                     EKLGGKSEIAIVTDLKSQIQMQRIDGFKDALKGSANVKILNSQPGYDREESLNTVENL
                     IQSNPDVDIIYATAENSVLGAKAALESAKNKDVKIVGFDLTEEASSGITDGTILAMIQ
                     QQPKEMGRLAVEAVVKAIKGEKVEKNIPVPALLYDKENIKDFKN"
     gene            complement(16132..17022)
                     /gene="rbsK"
                     /locus_tag="KOU88_002976"
     CDS             complement(16132..17022)
                     /gene="rbsK"
                     /locus_tag="KOU88_002976"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBK3212834.1"
                     /translation="MGNIVVIGSVNMDMVCSVDKRPEKGETVLGNSFFTSPGGKGANQ
                     AISASKLGANVKMISCIGEDGLGEELIRNFRTNKVDYSLVSRNNHKSSGVAVITLCEN
                     DNSIVVVPGTNELVDIELIKKNEEEIKNADIVLLQLEIPLKTINYVVNFCFENRIRVL
                     LNPAPAVKLNEDIIEKVTYLTPNEHEYKIVFDTNEGIEEVLKKYPNKLVITEGKNGAR
                     FYDGEEIKHVSCISVDVQDTTGAGDTFNGALAVAITEGKNLYTAVEYAVVVSGLSVTK
                     LGAQSGMPYKEDVEKYLNNK"
     gene            complement(17064..18077)
                     /locus_tag="KOU88_002977"
     CDS             complement(17064..18077)
                     /locus_tag="KOU88_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK3212835.1"
                     /translation="MSITIKEIGELAGVSKTTVSKVINNKDENISQATREKILKIMKE
                     KNYVPNKLAQSLVTKKTNTIGLLIPDIRNPFFTDVSRGVEDKANEEGYNIILCNTDED
                     AKKEYEGIRTLSERMIDGIIFAASSNTNWKEANYKDIKIPTVLIDKKISMNKETLKGI
                     VKINNFEGAYIATKHLLDIGNKKIIYLSGPLQNEIAVDRLEGYKKALIECNLSYNPAY
                     VFEGKYKIEWGQEFIKNLEKIDFDAIFCANDLIAIGVIRGLKERGLSIPNDISVVGFD
                     DIQTSSLISPSLTTVKQPSYDIGYKASEILINCLRGDKKESFDELIFKPELVIRDSTK
                     ESE"
     gene            complement(18306..19283)
                     /gene="bioB"
                     /locus_tag="KOU88_002978"
     CDS             complement(18306..19283)
                     /gene="bioB"
                     /locus_tag="KOU88_002978"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBK3212836.1"
                     /translation="MEKYIIKLKNKVLREKEISYEEALNLISLDTNNKNDFDILLKSA
                     NEIREYFMGRKADLCTIMNAKSGKCSEDCKFCAQSSYYKTGVEEYSLLDYNEILNRAK
                     EMESKGVHRFSLVTSGKGMSGKEFNNILNIYEGLRENTNLKLCASLGIIDYEQAKMLK
                     SAGVTTYHHNVETCRDNFHNICTTHTYKDRIKTIKDAKKAGLDVCVGGIIGMNESEEQ
                     RLKMAFEIRELNVKSFPINILNPIKNTPMENYDVLEPMEILKTTAVFRFIIPNVYIRY
                     AGGRLSLKGYDKVGFNGGVNSAIVGDYLTTVGSGIENDKKMIIEQGFEF"
     gene            complement(19489..19752)
                     /locus_tag="KOU88_002979"
     CDS             complement(19489..19752)
                     /locus_tag="KOU88_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212837.1"
                     /translation="MKIYYEKENSKKANVNNIPSVFAFNFLRNFLTSKEYEETRKEYF
                     INNLTKSQVNQAMKDLKWLFREYEGLEVITMESLDGVKTRIVL"
     gene            complement(19822..20895)
                     /locus_tag="KOU88_002980"
     CDS             complement(19822..20895)
                     /locus_tag="KOU88_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF362 domain-containing protein"
                     /protein_id="HBK3212838.1"
                     /translation="MEKSKVYFCDLYSNSQNKNVPNNVRRLFDEAGFKDLIEKNDQVA
                     IKLHFGEKGNTTYMSPVAVRQVVDKVKDCEGKPFLTDTNTLYTGSRTNSVDHLTTAIE
                     NGFAYAVVNAPVIIADGLYSRNYENVKIDKKHFESVKIGGEIYNSSAMIVMSHFKGHE
                     AAGFGGALKNLAMGCASAAGKQMQHSDVTPVVKEKKCVGCGKCVNSCPTKAISIVDKK
                     AVIDSDVCYGCGECPTVCPTRAVTIQWESDSDVFVEKMAEYAYGAVSNKKDKVGYITF
                     VMNVTPLCDCVPWSGRPIAHDIGILASTDPVAIEQACYDLICKEMGHDVFKHEHPHVN
                     GTRIIDYACEMGMGSKEYELIKL"
     gene            complement(21143..21901)
                     /locus_tag="KOU88_002981"
     CDS             complement(21143..21901)
                     /locus_tag="KOU88_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3212839.1"
                     /translation="MREYIAFTKKEFKENLRNYKLFSLIILFLIFGISSPISAKFMPD
                     LIAHFAPTLKVTAAPTALDSWTQFFSNISGLGMSLTLIIFCNILSNEYSKGTLVIMLT
                     KGLSRSSIVLSKFSVTVIIMTIGFWLSFLFAYGYTMYFWPTANLNHIIFSAFNLWLIG
                     IMYISVLILGCVLFRPAFASVLLVLVATLLLSLISIPKQIAPYTPNFLMSKNIDLISG
                     KVAMPEFIIPIIITVLISVVCLLAAVILFNKKPV"
     gene            complement(21898..22815)
                     /locus_tag="KOU88_002982"
     CDS             complement(21898..22815)
                     /locus_tag="KOU88_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212840.1"
                     /translation="MNIVSINGLSKGFGNRKIIDNLNFTVPEGSVFGFVGKNGAGKTT
                     TMKMVLGLLKPDSGTIDVCGEKVTYGKTSSNRHVGYLPDVPEFYNYMRPLEYLSLCGE
                     ITGLSKKEIQIRSEELLSLVGLRNEKRRIGGFSRGMKQRLGIAQALLSRPKLLICDEP
                     TSALDPVGRKEILDIMLKIKDSTTVIFSTHILSDVERICDHVAILNKGSIALSGTLSE
                     IKSMHGKDRLLLEFASNDEIQKFKSSDGIKSLLKDSEETNMEIVLHGKDIKAIQKTVI
                     STLAEMNLCPVKMELIELSLENLFLEVVK"
     gene            complement(22815..23015)
                     /locus_tag="KOU88_002983"
     CDS             complement(22815..23015)
                     /locus_tag="KOU88_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLDc_N domain-containing protein"
                     /protein_id="HBK3212841.1"
                     /translation="MENLMEYLPLLVPVIILDLILIITALVHVLRHPNYKIGNKAIWI
                     IVVLFISLIGPILYFTIGRGEE"
     gene            complement(23020..24114)
                     /locus_tag="KOU88_002984"
     CDS             complement(23020..24114)
                     /locus_tag="KOU88_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212842.1"
                     /translation="MNELNIAKTLILKRKEKGITQDELANYIGVSKASVSKWETGQSY
                     PDITFLPQLATYFNITVDELICYEPQMMKEDINKLYNKLCKDFTVKPFDEVMDEIREI
                     IKKYYSCFPLIFRMGLLIVNHYDIVDEKKRELLISEALEIFIRIQETCNDIDICRQAK
                     SMEATCYILLNQPIQVIDLLQNSNFPMINESILLAQGQMMNGQMDEARETFQLGAYQN
                     LISLVQNLVGILQNADKLQMKEIERRILAISDIFELDTLSPAIMLSSYLTQAQINLIH
                     GDNEGAIKSLRKYVDLATRDIYPIIIHGDDFFNKLDRWISEIGTGITRDDTIVKAGIV
                     AAIKNNPMFSVLSENKEYKFLIEKLSLLEE"
     gene            complement(24624..24764)
                     /locus_tag="KOU88_002985"
     CDS             complement(24624..24764)
                     /locus_tag="KOU88_002985"
                     /inference="COORDINATES: protein motif:HMM:NF021468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2185 domain-containing protein"
                     /protein_id="HBK3212843.1"
                     /translation="MNGEGCILSNKITKECYKVGYMIREKSIDTYPDSGWGFMTWDEN
                     GE"
     gene            complement(25074..26381)
                     /locus_tag="KOU88_002986"
     CDS             complement(25074..26381)
                     /locus_tag="KOU88_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK3212844.1"
                     /translation="MDISRSVDNSLNRTIEFLKELIKIDSQQGEPISQCPFGIGPKKS
                     LDKTLDYCASLGFSVKNIDNYIGYAEIGEGEELIGIPMHLDIVPPGEGWSVDPFSGAV
                     IDNIIYGRGVIDNKGAVSMLIHVLKNIEDMYPTINKRIRLIFGTNEETGMKCIKYYLD
                     KGEEIPSMGFTPDAMYPVVNGEKGRVHIRIEKEIKIDKSKPYIIVRGGTKENVVPSHC
                     TAKIINGIISELTTKGVAVHASNPEKGENAISKMVIKIVEDNMDFQHREDIELVSKYL
                     CSDYYGDALGINQYDEVFKNTTLNLGILKVNEEKIVCELDIRYGKNIVLNNIIDRFKK
                     VFCNGWKIEVIAHKDLHYVDESNLVLKKLLEAYEEVTDENGYTIAMGGGTYASWFKDM
                     VAFGPKFLAYKTGGHGVDERVPINHIRKNMEIYTLALIKLLEL"
     gene            complement(26446..26925)
                     /locus_tag="KOU88_002987"
     CDS             complement(26446..26925)
                     /locus_tag="KOU88_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-amino-thiazoline-4-carboxylic acid
                     hydrolase"
                     /protein_id="HBK3212845.1"
                     /translation="MSEKMYTEKEYLEGIRGATGERAVWFYLLMKEAEKLGANPDDIC
                     KEAIYGFGKMRGQKYNVADTPGKMAEMLYNSKGQKVFEMELVENTDENGVLKFHHCPL
                     DAAWKEYGLTKEERKEICRLACYGDYGRVDCAQGVKLDFAQKCAHDDEVCELVFTKK"
     gene            complement(26972..27835)
                     /locus_tag="KOU88_002988"
     CDS             complement(26972..27835)
                     /locus_tag="KOU88_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK3212846.1"
                     /translation="MQEIKNKEVKNGQGPTEVNKTRVLTKKDVTKTYLRWWWTAELSN
                     SFERMQALAVCASFTPALEKLYKRKEDLVDALKRHLQFFNTQAIWGGLIHGTVLAMEE
                     EKATEGKIPGEVISGVKNGLMGPLAGIGDTLDFGTFQTIFLALGASFGAEGSVIGAFF
                     PIMFSILLFCEGYYLFHLGYSLGRDSIKKILSGGIVNKIIDGASILGMFMMGALSATT
                     VKLSTPLSFDIGGKAIVVQDTLNMIAPGLLPLGVVFFVYWGMKYKKWTITKLLVILVV
                     LALVGSFIGIF"
     gene            complement(27835..28590)
                     /locus_tag="KOU88_002989"
     CDS             complement(27835..28590)
                     /locus_tag="KOU88_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3212847.1"
                     /translation="MESVLMLAIVTGLWYWFAAGLAGYTLFSTLKSPLFIGFSLGLLW
                     GDVTTGMIVGASIEMVYLGMVAAGGNIPSDKCLAALIAIPVALQTGVNAEVAVSIAVP
                     LGVIGVLVNNLRRTGNAVLVHKADKYAEEGNTKGIWRCATLYSLIFGFVLRFPIVFVC
                     NFFGADLVQSLLDVIPQWLMNGLTVMGGILPALGFATTIFTIGKNKFLPMFIIGFFMV
                     QYFEISITAAAIFGVCIALLITFMKEDKRVGEV"
     gene            complement(28617..29105)
                     /locus_tag="KOU88_002990"
     CDS             complement(28617..29105)
                     /locus_tag="KOU88_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3212848.1"
                     /translation="MAKITLVRVDHRLIHGQVITKWVKIAQAQKIIIVDDFLGQDEFM
                     ADIYKMAAPSGVEVVILTAEDAGQAFQNNTLGDKNIFILFKNVDMANKAYKAGLKYEK
                     IQLGGIPNEAGKKMVFTAVSLGNEDVEQLNELNENGVEIVLQVIPEESSMTYENALKK
                     FK"
     gene            complement(29123..29524)
                     /locus_tag="KOU88_002991"
     CDS             complement(29123..29524)
                     /locus_tag="KOU88_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBK3212849.1"
                     /translation="MNKYKVIILCHGTWGKVLVEETNKNFGLSNQYEVLSLSSEKDVS
                     VFMKEVEEVVDKEDVKIIISDLYGGSTSSVAIAVAIRRGIDAINGLSLQTILIVDEEL
                     SKEDKLHTLPERIVKKNNNLCVDLIKEFKKI"
     gene            complement(29527..30024)
                     /locus_tag="KOU88_002992"
     CDS             complement(29527..30024)
                     /locus_tag="KOU88_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3212850.1"
                     /translation="MSLVKYCRCDDRLIHGQVIYKWVKHLGVKKIVVVDDETTNDVIA
                     KGLIKMAAPKNIDLSILTVSESRRYFYNNQADDNVFVLIKNLDTANRMIEEGINIKKL
                     IVGRIPTGIGKKKISQNVYINKKEFLLIDEFIKKNINVSIQMVPDEEEVELNQNINRY
                     KGEFI"
     gene            complement(30048..30452)
                     /locus_tag="KOU88_002993"
     CDS             complement(30048..30452)
                     /locus_tag="KOU88_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3212851.1"
                     /translation="MIGIIVMTHGSFSEEIIKSCELIAGPAERTAAIKLNRNDNIEDL
                     NKNFVEKLNELDEGDGVLVLADLLGGSPSNVASLNLKKGGKFHALTGVNLPMLLEALI
                     NREGKSLEELAEACIEAGQTGINNINKVLSSM"
     gene            complement(30682..33249)
                     /locus_tag="KOU88_002994"
     CDS             complement(30682..33249)
                     /locus_tag="KOU88_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3212852.1"
                     /translation="MTQKKLSRKEKVLICLKRLTEEHLNFNNGIRFGFDAEYIATEVG
                     INRSNASKELNQLIKESIIIKIKGKPVQYLYKESIESILGKKLNKGIFDNINSINEYS
                     ENDSIKDEYILESIKKENNIFNLVGCDGSLRSQIEQAKAAVIYPPKGLSTLIIGPTGV
                     GKSIFAEYMYKYSLTIKEDSDNAPFIIFNCADYSDNQQLLLAQLFGYVKGAFTGADKD
                     KYGIVHEANNGVLFLDEVHRLSAEGQEMLFLLMDKGIYRRLGEANKVHECRVMIIAAT
                     TEDPETAMLETFLRRIPVTIKIPSLEERGFQERMKLICYFFKEESVRIGVKLKVSKEV
                     IKAFILYKCKGNIGQLKSDIQLICARAFLDYMTYKRECVYVRLSLLPNNIRESLYGNN
                     RKEEFVQNFSFIGKDDIIFLPEEKDFESENLLIENKKYDLDFYGMIKETWNKLQQEGI
                     KESQIRSVIDGDIQKYSYNLMNTFIYNSSNQTAYNNIVNDSIATTVKYILQKHDKWSK
                     REGLDKLIKAIALHIQNLIERIKIGNIVKHPNKDEIMKERAYEYNIAKEILSNMSLMY
                     GVEFPEDEAIFLATFLYLSYVGLNEESIAILVIMHGESTASSMVNVANTLLDCNHAVA
                     INMGLEDRVQDILVQAVEIANKIDKGKGILILTDMGSILTFAKVIRDATGKEVKAIDM
                     VSTPIVIEATRKALTPEMTLEKLYFNIIESIKKHYGDMEVTYAEKDNGGRYFDRLLID
                     NISKTLTFLNGEKAYFILKEVINRISEHYSLVIQDELLVKFIFHCSCMIERVIIKESL
                     VYKSYEERISRNKELYLVIKESFKLVEETFDIIISDMEYANILDIFESQYDTDKFKS"
     gene            33415..34158
                     /locus_tag="KOU88_002995"
     CDS             33415..34158
                     /locus_tag="KOU88_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBK3212853.1"
                     /translation="MNFLSDLHTHSIVSGHGYSTLLENINYCKENGIKILGTSEHGPK
                     MPGSPHKWYFHNIQNIPRIINNIIILRGCEANILDIKGNIDLEPFVIPRLDYLILSFH
                     EAVFSPNTLENNTKALINAINKHDNIEILGHLGNPNYPIDYELIIKLAIEKNILIEIN
                     NCSIKGVSRNGSSDNCKYIATLCKKYGAKIILTSDAHICFDIGNYEYSENILKEINFP
                     DELIMNYPKKLINHFHQKGKLLDVDYTNI"
BASE COUNT        11153 a         6327 c         3542 g        13463 t
ORIGIN      
        1 aaattatttt ttaaaaatat ttactttctt atattacata atttattgaa tggcagtcat
       61 actgttggtt tagagtattt taacacacac attttgttgt aaaaattaca actattaata
      121 taatatatat acaatcataa gtattataat ttttatgaat ctaatttaaa cttaatataa
      181 acttattaat aaaccttcta tgtctaaatt ttaaaattac aatataaaag ctctacacta
      241 aataaataca ttaaataaac ataatggata atgaatataa atttatatat gcaaagcgct
      301 ccaataaaaa ggtaccaata aagttaaaag aaacttattg atacctttca ttattacata
      361 cttcaatata taattataag ttttttaaat agtatggatt tacatttatc ccttatctca
      421 tagctctcat agcatttact actgctataa gtgccacacc tacatcagca aatatagctt
      481 cccacatagt agctactcct ccagcaccta gtatcataac tataattttt actcctagag
      541 caaatattat gttttgccac actatcttat tagtcttgtt tgctatttca attgctttag
      601 atatcttgct aggctcatct gtcataagca ctacatctgc agcttcaata gcagcatctg
      661 aacctaagcc tcccatagct ataccaacat cagcacgagc taatactgga gcatcattta
      721 ttccatcacc tacaaacgct attttctctt tttcagttct tccttcatat aaatcttcta
      781 atctatctac cttttcatta ggaagtaaat ttgagtaaac tgtatccaat tctaattctt
      841 gagcaatatt ttttgctact ttctcattat ctccagttaa cattacaact tcttttaccc
      901 ctatttcttt taagcttctt atggcatttt tactatcttc ttttacttca tcagagataa
      961 ctatataacc tctatatact ttatcaacag caatatagac tactgtgcct acttctttag
     1021 ctgatgaata agatatattt tcttttttca taagtttctc attacctgct aatataaaat
     1081 tgccattatg ctttactcta attccataag ctgctatttc ctcataactg tctattgtat
     1141 ctaaatcaat ttttttatta tagtaactta atatggactt tgctattgga tgatttgaat
     1201 ttacctccgc aatagctgca tattctaata attcttcttc tgatatacct tcaggattta
     1261 acttagttac attgaacaca cctttagtaa gtgttcctgt tttatcaaat actactgtat
     1321 ctacacttct taaagcttct aaatagttac ttcctttaat aaggatacca tttttagatg
     1381 caaacccaat tccactaaaa aaactaagtg gtattgataa aactaatgca caagggcaag
     1441 aaacgactaa gaatatcaat cctctatata accaatcact aaatacctca cctgagatta
     1501 caagtggtgg cacaaatgct attaataaag cagctattac tactattgga gtatagtatc
     1561 ttgaaaactt agatataaag ttttctgtct ttgatttttt aatgctagaa ttttcaacaa
     1621 ggtcaagaat cttagaaact gttgattctc caaaactctt tgtaacttca atactcaata
     1681 aagcattttt atttataaca cctgataaga tttcatctcc tttttcaact tctctcagca
     1741 ctgactctcc tgtgagtgca gaagtatcta acatagaaac tccatctact actacaccat
     1801 ctaatggtac tttttcacca ggttttacta ctattatatc acctacattt acctcttctg
     1861 gtgacaccac cttaacttca gaattaactt ttagatttgc atagtctggt cttatttgca
     1921 taagtgaagt tatagacttt ctggatttac caactgcaac accttgtaaa tactctccta
     1981 ctttatagaa aagcataacc cctactgctt ctgataactc ccctattgtt aatgctccta
     2041 ctgttgctag agccatcaaa aagttctcat caaatactct tccttttgat atatttctta
     2101 ttgctcttaa aagcacatca ccacctacta ttacataggc aactataaat actatattgc
     2161 taaactgact ttcataacct gtagctgttt gatatatacc aaatatatat acaagtgctc
     2221 caattataag tggaattaat tctttcttat ttgtatcatt tacagctcct gatttttcag
     2281 tagttctccc ttttactttg tcagtagacc ctacttgtat atcaagccct ggctctgttg
     2341 aatttattat ttcttttatt ttatttataa catcatcctc ttcaaagtta ttacttatat
     2401 ttactgtaag ttttttattt acaaagttta aattagaaga ttcaacttct tttaatttag
     2461 aaactttgtt attaatctct tctgcacaat gagcacagtt taatcctcct aatataagct
     2521 cttttttaat tgatgtttta ctagctgcat tttctttaga acttatttgt atatcaagac
     2581 ctggctctgt tgaatctatt atatctatta tcttttctat agtagtatcc tcattaaaac
     2641 tttcctttat atttactgta agttttttat ttataaaatt taaattggaa gatttaactt
     2701 cttgtagttt agaaacttta ttattaatct cctctgcaca gtgagcacaa tttaatcctc
     2761 ctagtataaa ttctttttta attgaattat ttgcttccat atatattcac tcctctcatt
     2821 tatcatttat aagtctctct aatatgattt aatccacaat caaatatctg acttatatga
     2881 ctatcatcta atgagtaata cactgttttt ccttctcttc taaactttac taatctagcc
     2941 tgctttaata ctctaagttg atgagatatt gcagaatgag tcatatttaa taaactcgct
     3001 atatcacata cacacatttc atttgcaaat aatgcatata atatctttac tctagtagta
     3061 tccccaaata ctttaaataa ttctgctaaa tcatataaca tttcttcatc tggcatagtt
     3121 gatttagcct ctgttactat ttcttcatgt actatattac aattacaatc atttatctct
     3181 tctctcattt ttaatcctcc attattttaa tatatgaata actgttcata tgttcattat
     3241 atgttatcat ttctaaattt gcaacaataa tttttattaa tttaatataa atagaatgca
     3301 catattataa acttttttaa tatatatatt attagaataa gtttttgtaa acttttttat
     3361 agttttctag gaggtgcaag tttaatatga gtaacaagaa aaaaaaggat ttagatacta
     3421 gttacatgcc ttacttagac ccagcgaact atgcagatta tattactaat gaagaaattc
     3481 cccaagatga attgagaaat gaccctcaaa tttctaatgg ttatacaaaa atacctaata
     3541 accagaacat aaataaccta tatcctaata atgtaaatca ttatcctaaa agtagtaatt
     3601 ctccaaacaa cttgcctaac acaaataata catccggaaa tatgaattac aatacatctg
     3661 ctacaaataa tatgcctaat aacatgaata ataatacggg tatgcctaat aatatgtcta
     3721 acaatatgaa tagtaatatg ggtatgccta acaatatgcc taataacatg aatagtaata
     3781 tgggtatgcc taacaatatg cctaataata tgaatagtaa catgggcatg cctaacaatg
     3841 tgcctaataa catgaatagt aatatgggta tgcctaacaa tatgtctaat aatatgaata
     3901 gtaatatggg catgcctaac aatatgtctg gcaatatgaa taacaatatg tatggtaata
     3961 caggtatgcc taataacatg aacagtaata tggggtataa tatgaacaat actatgggta
     4021 ttcctaactt ctcatgtaat caaaatatgc ctcctaatgt acttatgatg ataccaggag
     4081 ttatatgtca taatacaatg caaggtatgc ctgtagttat gcctagtact atgcctccta
     4141 atatatatcc tactccttat ggttctagta atatgtctgt acaaggtata ccacaagcta
     4201 ctaatattga ggaatttgat gaggaagaaa tgtaatatat atttttttaa gtaagttgta
     4261 taaaacatta ataattgacc ataataataa atgtattcct cataatattc ccccaatatt
     4321 attataggta tagaaagttg actgaatatg cgcttattcg gtcaacagat attaacataa
     4381 tctaataaga taaacataga aaaagtcaga taaaatttaa ttttatctga ctttttcatt
     4441 taaaaatgct ctcttgtgtt ggtgattcag aatagtatgg tactcgtatt tgagactaat
     4501 attggcaaac aacataaaga aaaatataaa ttttttataa taaactgtat aaaattttaa
     4561 taattgacca caataataaa tgtattcctc ataatattcc cccaatatta tagaaataaa
     4621 tttaagcgag attaaattca gttaatctcg cttaaataat gtctaaattt attattccaa
     4681 aaaatcatca aaatctaatg aacctgattc tgcaaaatca tataatgcat tttgctcaaa
     4741 gaaaaatttc tcttcaaatt taatatagtc gctataatta gattgactta tttcattgat
     4801 ataattgcaa tcattttcgt tataagtacc aataaaaaac ttatttccca ttaagtaata
     4861 tatagctttc atatcattat ttattatata tacattttct tttacatggt cattattaaa
     4921 attaaatcta gtaaagaata taccttcatt catattactt tttaacagaa atggattttc
     4981 tctataaaat actcctgcaa attcttcagg tgaatttaca ctgtaaacac ttacaaattc
     5041 acttttagaa atctcatcaa atacctcaaa atcatacata ggttctttat ctgtcactaa
     5101 tagagaatta attctaaaac cagtttcata acacttactt atgcaaaaag caattttaca
     5161 tatataatat ccatcattat cttcatataa agcttcactt atatatctgc cttgaccttt
     5221 atcacttacc acgtttttaa gtaatgttcc atttatatta gtaatgtgca tatttgcaat
     5281 ctcgtcactt ccagaaaagt actttaaact ttctctatcc catgctataa atctcatggt
     5341 catatagttt ataaattcaa cttcctcgtc aactctttta catattttat tgtataattt
     5401 ttctatagtt aaatctgttt tatagttttt tataatatca atatactcac atttatctcc
     5461 tggcaatagc ttatcataat aaagattctt attaccaaaa taagatacta aaaataaaga
     5521 ttcatccttc gttaattcaa ctctatctga accaaatcct cccatcaatc tttcttcttc
     5581 catataagct tcttcttgtg ttgggttatt taaactcaca taatccgcta atcctaatcc
     5641 ctctgcatct aataaaaaat attgacaaaa gtgattgttt tcatcatcta tccaatttat
     5701 tataagacct aaactgccca taagtctaga atttgtagcc tttgcaaaat taaaattcat
     5761 atagtcacat cctttaaact ctaaaatact tgttttttaa tatataaatt attatacata
     5821 tattttaaca acttagatac aatttataat ataatataag gaaatgatta attgaggtgg
     5881 tcttatgaaa aatatagcag ctttttttga tatagatggt actctttata gagactctct
     5941 tatggttgaa cattttaaaa aattaattaa atacgatata attgaccaaa aaaattggta
     6001 taaacatgct agagacactt ttatggattg ggataaaaga caaggtaatt atgatgatta
     6061 tctattagaa atatgtgacc tttatgttga ttcactaaaa ggattagata aaacctgtat
     6121 caactttaca agtgaccaag taattaaatt aaaagcagat agagtttata aatacacacg
     6181 ttcaaggatt gagtggcatc taaatcaagg acacatagtt atatttatat ctggtagccc
     6241 tggatttctt gttgaaaaaa tggcaaaaaa atataatgta accgattttc taggaagtga
     6301 ttatgtcttt gaaaacaata tatttacagg cacagttatt ccaatgtggg attctataag
     6361 taagaataat gctataaacg attttgttgt aaagtatgat ttagatttat caaactcgta
     6421 tgcctatgga gatactaatg gtgatataaa tatgctaaaa agagttggaa atccaatagc
     6481 aataaatcca acaaaggaac ttttatctca aatatcactt gatgaggaaa tttctaaaaa
     6541 tgttgagata atagtagaaa gaaaagatat tatttattct ctatctacag atgtaaatat
     6601 agtggatatt taatttatac tatctatttt aaaaacttat attatatcta atatttatat
     6661 ctaacatata aaagctttga ctaaaaatca aagcttttat atgttgcact aagaatatat
     6721 taaatttagc tttatgcttt aatgtatatt catatatatc atttacactt atctaaacta
     6781 caatttcatt aaaattaaat ataaaaatca actattattt tttaaatagc atctttctta
     6841 atctattatt gtaataacct ataaaagaac tgtaaacata gtcatatact ataaaggcta
     6901 tctcaaatga acctataata aatatgttta ttggaatata aactattgtt cttaataaaa
     6961 aatacaatat aagtatcatt atatttgcaa atactaattt cataaaatac tcaatatata
     7021 tagacctatc tttttctata agatatttta caataccata tattccaaag gtaagtgaat
     7081 atacaatcca ttgagactta cttgccatca ctataaatcc taaaactata gaacctatat
     7141 aaaaagcaat tccactctta aagccccatt ccattattac aattgatact aaaagtgatg
     7201 ctaaccccat aataaacaat gtatttacag gaataatgtt tgtaagagtc aacaatatca
     7261 catttaatgc taataaaact cctccataag caacttttat actcatattt atcatcctaa
     7321 caacaagtta ttaaatctcc accaaaacat tcacaacatg aatctaaaca ccaaagttta
     7381 gcacaatttt cacaacaatc gtcacctaga caacaacagc aatcatcaca gcaacagcaa
     7441 caacatccat ctaaatcatt acgtcttctt ctattataat tgtcagccct attgctataa
     7501 tcatttctat attgtgtata acttctaagt gcatcactat attcactatt ttcaggctcc
     7561 ataaattttg ctctttttaa gaagtcttca ccttcttcat aatatcctat gttcattgca
     7621 gaaaaaccag ttaaataata ccactctgca catttgtcag tcaaagtttt taaaaaatca
     7681 tatgcttttt taaattcact attttctatg aatgatcttg ctctcataaa attttcatta
     7741 ttataagtat tactgtacat tctttccacc tctactttct aatatattaa tatatcttaa
     7801 ataaacacca gaataaatta tattttctat tattccaaca tttttattta gatttagatt
     7861 atcaattccc ctagctaaaa atcctaatga tgttactatt atttttttta ctttttcttt
     7921 taactcatca tttttatcaa tatactctat aaatggatta tatcttcctt tcttaaaatc
     7981 ttcatctaaa tcttcatagg catctagtag atatatatac ttacctatat taaaacctat
     8041 cattcttaag tttctctcat tttcatcttt tttatagaca aatacttcac ccattatatt
     8101 tccaaatata ctagatactt catctatatt tatattttta tctttttcta acttatttaa
     8161 ttcatttagt tgttgtttta tatactctgc tttttcagga tacttttcat atgctaattt
     8221 taatttgttt ttatatatat aatatgccaa tttatctttt atgcgtttat catccattaa
     8281 attatcttcc aatttataat acgttaaaag aatattcata cttgctgcat attctgtaat
     8341 atcatttgta attacctttt tctttttaaa tggatttact atacacactt cctctgtact
     8401 tatagactct gggttatata ctgctgttaa taaaacaatt aaaaatgtta tatcatagtt
     8461 caaagaaaac ctagagattt ctccatgatt tctttttaag tatttacata gtccacaata
     8521 gtaagctttg taataatcat attctctaaa tgttaaatcc attttgttta ttttaacata
     8581 tccaaacata aatactcctt tttgtactat tttttattta gattatatat agtataacac
     8641 tttttatcaa gattatataa tttacagtat tctaagaaac ttaaaaaatt ccttctaatc
     8701 attgtatctt aaatttaaaa taattagaag gttgggttaa aaataatatt aaattatata
     8761 cttatattaa ctcatacaag ttagttatgc ttatatcaat ttaagtttta aataattggt
     8821 atatatttaa aactacctac agtatccttc aattcttttt ttgctttgtt tataaccaat
     8881 tcatcaagca ttacatcatt tattgaacat gatatagatt tagatgccaa taacattgcc
     8941 ttaaatccca tatcagaacc tgcactggca caagattgcc atgtatgggc agaaatacca
     9001 ataggccaaa ctgaacaaga acactgtgct gtaggaatta tgtagctaac atctccaata
     9061 tctaatgata atgatataca gttattatga gtaaatgtat catccgtaac ttcatcatgc
     9121 agattcatct tagtaatatc cttatttcca cttaatacac tagaaacact acttctttta
     9181 tctatagaca ctgtctcagc taatttatct gcaaaatagt agtcatcttc attatagttt
     9241 tgcacaccta ctaatttcat attttgtgat agaatatctg ttaatattgt atttggaata
     9301 tagtcatata ctccacttat aatgtcatat tccataatag taccagtcat taatgctgct
     9361 ccttttgcta tatcaacaat cctaccaaat acatctctta catgctccat tttaactcct
     9421 cttatgtaat accacacttc tgcaaaatca ggaactatat ttggcatttt tccaccatta
     9481 gtagttacat agtgtactct acaattatca aatatatgtt ctctcaaata attacaacct
     9541 atattcataa gttctactgc atcaagtgca cttcttccgt tataaggagc ttgtgctgca
     9601 tgggcactaa tcccattata tctaaatttc acagagtaat tagcaagtgt tggtattctt
     9661 attggagtat ttatatcaaa tggatgccaa ctaaaagcac aatcaattcc atcaaaaaaa
     9721 ccttttttta tcatcaatac ttttccagat aaatcttctt ctgctggaca tccatagtat
     9781 tttatagtcc ctttcagctt ttttagtttg attaattcct ttactgcaat tacagctcct
     9841 attgaacctg taccaagtaa gttatgtcca catccatgac ctgcaccacc atctacaata
     9901 ggttctttag tagtggatac tttttgagac aaaccatcta aagcatcata ttctcccaaa
     9961 actgctataa ctggtctacc ttctccataa ctagccacaa atgctgtatc cataccttct
    10021 aatccctcta tactaaaacc atgttttttt aaacattctt tttgtaaatt tgaagcatag
    10081 tattctttat actgaagttc tggatttttc catatcttat ctgatatatc tcttaattct
    10141 ccctgtatct catctatata ttccatcaaa aactttttat ttaaattatc catattaatt
    10201 atataaacct ccctgtttct aataacttat cgattatcag ccaaaatgac taattttaac
    10261 tgatttaaaa atattttcta ccatacaacc attttataca ataaaacctc ttgacttgta
    10321 agtttcattt tatcaagtaa gaggttttca agttttataa aatttttagc atgttaacca
    10381 atcaagcata ttaacccata atttattata gtatttccaa tcagtaaatt cttttggacc
    10441 ccagtgaggt gcacagtcag aactaaagat agcagatttt ccttttccaa actcgccaac
    10501 agctacaaat gggtctcctc caatagttgc taaaacagga caattatctc tagctactgt
    10561 tttgttatat cctaaaaact ttggccattc tgttggtata ccttttaata ctggatgttc
    10621 agagtcaata acttctggaa ttattcctgc tggtttttca actctatcat ctttatctat
    10681 cattgttatt ggtaatacat ctttgatagc agtttctcca aatctagctt ttgcatctat
    10741 tcctgtaaat gacatatatc cacctaccat gattaacgcc ccaccattat ttacatactc
    10801 tttgattagt tcaagtctat ctggattact attgcaatct ataaaagtac tattagataa
    10861 taagaacgta ttagaaccta tatcagataa tattatacag tcatactcat ttaactcttc
    10921 taatttatac ggaaaactat ctgctgctac atgtgcaggc atatgaactg tctcatatcc
    10981 tccagattct attgcttctt tcaaccactt tacagcttct tcataatgag ttgtaacaaa
    11041 cgtatcaaac ccttttatat gagttatatt ttttacccaa gattccccta ctattaatac
    11101 ttttttcatt tatatattcc tcctactttt ataagtttaa tattagactt gcatacataa
    11161 gtatactatc taaatactcc ttaatttcaa catattcatc aattgaatga cattgttcta
    11221 ttgaacctgg ccctaatata agtgttggta tttcagctaa atttttcatt actctcgcat
    11281 cattgccagc tgttgaacct tttatctcta atttttttcc tagagtttct tctagtattt
    11341 tatgtgcatt cactacaaaa tcagaatcct tgtccatctc aaaacctaac cctgattgat
    11401 atatgtttat atttggttta ttatctttaa gccataaatc tccattagcc cttgtcatta
    11461 tgacatttgt tacatcattt acaacttgtt cataactcat tatatttggc aagaagtgta
    11521 cacataaatt aaatacacac ttatctggca cagtagaacc tgctgttcca ccatttatta
    11581 cacctaaatt tattgtaggt gaaggtaata gtggatgttt atatatcata agccagttat
    11641 gttccaactc ttttatatct tgaagcaaca acatagcctt ctcaattgca tttacaccct
    11701 cccacttact accacagtga agagacacac ctttaacctc aacttcaaag aatacaaatc
    11761 ccatatgtgc aactattaag ttttgttctg atggttcaca aattatgcaa caatctccat
    11821 caataccatt cataactgca tttatggtac catttccgcc accttcttca tctactactg
    11881 acattatttt tacattacca ggtacattta gaccactatc ttttataagc tttacagcta
    11941 atattgatgc tataagtcca gatttcatat cagcagttcc aagaccataa agttttccat
    12001 tatcttctgt agcacgatat ggattatatt tccacttact tatatcaccc ggtggcatag
    12061 tgtctacatg accattaaat acaattgtct taccaggtaa atcatcacta tacttacaaa
    12121 ttaaattata tctatcttga taattgtgac ctagatttcc ttctttatat atattttttg
    12181 cttttttaat taattcttcg ctcatttctt gtctatccac actaaaacct atgtaatttg
    12241 caagtttttc aatatattcc tgtccttctt tttcaaatcc acctagtatt ccatgaccaa
    12301 catcttcagt ctttatactt acaagttctt ttaaataatc tatgtattct tgttttttac
    12361 tatttaatgt atctaagaga atttttttca tatttcctcc taagatttat ttttacattt
    12421 aaaatttcaa gtctaatctc atctatttaa gccatagtaa actttttcac ttagcatatt
    12481 ctcattcaat gtataaagat gtatgcaaat taaagtataa aaatatatac aaaaacttaa
    12541 taatttttat agtttataag ctaaaattta attactattt agatttagct gattttttta
    12601 attttatatt atttatccat atagcaaata acattaccaa accttttata atcatttgat
    12661 tatatgaaga tacacttaat aagtttaatc catttcctaa tattcctatt attccgacac
    12721 ctatacatgt acctactata gaaccagaac cacccatcat attagtacca ccaagcacaa
    12781 cggctgctat agcatccaat tctgctccat ctccaacagt tggtgaacct gatgccaaac
    12841 gtgatgatag tattatccca gctaatgctg ttagtagtcc agctagtgcg tatactttta
    12901 ctataacttt atttactttt actccacata atctagcggc ctcttcattt ccacctactg
    12961 catgtacatg acgtccaaaa ttagttcttt ttaatagaaa atgtcctgct attacaacta
    13021 taatcataat tataactggt attggtattg gtccaatata tcctctaccg agcatcttaa
    13081 atgcatctgt atttactgat ataggtcttc ctcctgtaaa tacaaagctt gccccactta
    13141 ttatcgttaa catggctaaa gttacaatga atggaggtag tttttgtgtt gaaataattg
    13201 caccttttat gactcctaat attgtcccta ttgctaatgc aagtatcata cctacccata
    13261 taggtgcatt ataattcact actgttgtag cccaaaatgt acctactaaa gcaattactg
    13321 ctcctacact taaatctatt cctcctgtaa ttattacaaa tgtcatacct actgcaagta
    13381 ttgcatttat tgatatttgt cttccaacat taattaaatt atctaaagtt aaaaagttag
    13441 atgaagctac actcattatt ataaaaatta ttacaagtcc tacagctgca ctcccttggt
    13501 ctctaaatac acttgttaat tttgtcaata atggagaaga tttttcttct ttatgcttag
    13561 ttattgaact cattaatttt acctccgaaa gccaatttta atacattatt ttcaaccatt
    13621 tcttcacctt ctaaaaatcc acttatatga ccttctctca taaccattat tctgtcactc
    13681 attgatatta attctggtat ttcagaagat atcattatta tacttacacc actctccact
    13741 aaatctccca ttagattgta tatctctgcc ttagcattta catctatacc tctggttggt
    13801 tcatccataa tcaatatatc tggttgtaat aaaagccatc ttgctattat agctttttgt
    13861 tggtttccac cacttaaact ttgtataact tgattcatat gtggtgtttt tatctttaaa
    13921 gcttctatgt atttttctaa aatctctttt tccttttttc tatctataat tgatttaaac
    13981 ttagatatct tttttaaccc agccatagtt gtattttctt tgacactcat ttgtaaaaac
    14041 aatccagtac cttttctatc ttctgttatt aatcctagtc cattttctat tgcatctgat
    14101 ggagttttaa actttacttc ttcattgttt aaatatattt ttccagaatc atatgttcta
    14161 agtccaaata tagcttctac tatttcactt ctcttacttc caactagtcc acctattccc
    14221 aatatttcac cttttcttat attaaagcta atatcattaa aaacattgtt cttagttaga
    14281 ttttccactc gcataatttc ttcttttatt tctacttttc tttttgggaa aaattggtct
    14341 agctttctat ctatcattaa attaactaat tcttcctcag acgatacatc tttggtattt
    14401 aaagtcgaaa tcgttttccc atctcgcatt atagttattc tgtcacaaat ctcaaagagt
    14461 tcttccatcc tatgggatat atatattata ctaactccac tctcttttaa atcatttata
    14521 agtctaaaaa gtatttcagt ctctttttta cttattgaag aagtaggttc atccattatt
    14581 aatactttag tttctgatga taaaactctt gctatttcta ccatttgttt ttgagctata
    14641 ctaagctctt tgactaaact atttggattt atatctattc ccatattatc gaaaatcttt
    14701 ttagcctctt cattcatttt tttgtcattg gttaagactt tgccatttat ttcttttccc
    14761 ataaaaatat tttgtgctac tgttaattcg tcaaaaactg ttagttcttg atatatggca
    14821 tttataccta tctttttaga gatatctggg gatatattct ctatttcttt gccttcaaaa
    14881 ataaattttc cagaagtttt cgaatgtgca ccagttaaaa tctttatcat tgttgattta
    14941 ccagcaccat tttcacccag tagtgcatga acttcgccat gaaataactc aaaattaaca
    15001 ttatctaatg ctctgacacc aggaaattct ttagcaatat tacttaactt cagaattata
    15061 ttactcataa tgacactcct ttttaaatag gatttctttc aaataatctc attttatttt
    15121 actaattctt aaagtctttt atattttcct tatcataaag taaagctggt actggtatat
    15181 tcttttctac cttttcccct tttatagctt ttactactgc ttctacagct aaacgtccca
    15241 tctctttagg ttgttgttga atcatagcaa gaatagttcc atctgttatt ccacttgatg
    15301 cttcttcagt taagtcaaat cctacaatct taacatcctt attttttgca gattcaagtg
    15361 cagctttagc tcctagtaca ctattttcag ctgttgcata tattatatct acatctggat
    15421 tagattgaat taagttttct actgtattaa gagattcttc tctgtcatat cctggttgtg
    15481 aatttaatat cttaacattt gctgaacctt ttaatgcatc tttaaatcca tctattctct
    15541 gcatttgtat ttgagatttt aaatctgtca ctattgctat ttctgacttt ccacctaact
    15601 tttcatctat gtatttttta gtgtattccc ctaatttttt accagcatca taactaactg
    15661 ttcctacata acttgtaata ttttcagtat ttaatacagc atctactgta actactggca
    15721 ttttttcaaa tgctccttct actgctggta ctatagccga attatcagtt ccaagtacta
    15781 tcattccatc tacattttgt tgtataaaat cttctattgc tgatgtttgc ttagctacat
    15841 cttggtctgg gtcatttact ataactttca cacctaattc tttagctttt tcttttattc
    15901 cctcatcaat atctataaaa aattgatgtt gaagagttat tgtagatact ccaatagtta
    15961 aatctttctt gtctgaacca cctttattat ctgatttact tggtccttcc attgaacacc
    16021 ctgttaacat tcctattgct agtattccag caattcctaa agataaaatt tttctcactc
    16081 tcataattaa cctccatttt taatagtttt aaatttgaac aaattagatt tttatttatt
    16141 atttaaatac ttttcaacat cttctttata gggcatacca gattgtgcac ctagtttagt
    16201 tacagaaaga cctgatacta ctactgcata ttctactgct gtatataaat ttttcccttc
    16261 tgttatagcc actgccaatg ctccattaaa tgtatctcct gctcctgtgg tatcttgaac
    16321 atcaacactt atacaagata catgcttgat ttcctcacca tcataaaatc tagctccatt
    16381 ttttccttct gttattacaa gtttatttgg atattttttt aatacttctt ctatcccttc
    16441 atttgtgtca aaaactatct tatattcatg ttcatttggt gttaagtaag ttactttttc
    16501 tattatatct tcatttagtt ttactgctgg tgctggattt aataaaaccc taatcctatt
    16561 ttcaaaacag aaattcacta cataatttat tgtttttaat ggaatctcta attgtagcaa
    16621 tactatatct gcattcttta tctcttcttc attcttttta attaattcta tatctactag
    16681 ctcattagtc cctggtacaa caacaatact attatcattt tcacataatg ttataacagc
    16741 aacaccagaa cttttgtgat tatttctgga tactaagcta taatcaactt tattcgttct
    16801 aaaatttctt attaactcct ctcctaagcc atcttcccct atgcatgata tcatttttac
    16861 atttgctcct agtttagaag ctgagatagc ttgattagcc ccttttcctc caggtgatgt
    16921 aaaaaaacta ttacctaata ctgtttctcc tttttctggt cttttatcta cagaacatac
    16981 catgtccatg tttacacttc ctatgacaac tatgtttccc attacattac tcctttacat
    17041 atctatttat gtctctcgtg ctgttattca ctttcttttg ttgaatctct tatgaccaat
    17101 tctggtttga aaatcaattc atcaaacgat tcttttttat ctcctcttaa acaatttatc
    17161 aatatttcac tggctttata tcctatatca taagacggct gttttactgt ggtaagagaa
    17221 gggcttatta gacttgatgt ttgaatatca tcaaatccca cgacacttat atcatttggt
    17281 atacttaatc ctctttcttt aagacctctt atgacaccta ttgcaatcaa atcatttgca
    17341 caaaatattg catcaaaatc tatcttttct aaatttttta taaattcttg tccccattca
    17401 atcttatatt ttccttcaaa tacataagca ggattgtagc ttaaattgca ctcgattaga
    17461 gcctttttat atccttctaa tctatctact gctatttcat tttgaagtgg accacttagg
    17521 tatattattt tcttatttcc aatatctaat aaatgttttg tagctatata ggccccttca
    17581 aagttattta ttttaacaat tccttttaag gtttctttgt tcatacttat cttcttatca
    17641 atcaagacag ttggtatttt tatatcttta taatttgctt ctttccagtt tgtatttgaa
    17701 gatgctgcaa atataattcc atctatcatc ctctctgata gtgttcttat tccttcatat
    17761 tcttttttag catcttcatc tgtattacat aaaattatat tgtagccttc ttcattagct
    17821 ttatcttcta cacctcttga tacatctgta aagaatggat ttcgtatatc tggtataaga
    17881 agccctatag tattagtttt tttagttact aaactttgtg ctaatttatt tggtacataa
    17941 tttttttcct tcattatttt caaaattttt tctcttgttg cctgacttat attttcatct
    18001 ttattattaa tgacttttga cacagttgtt ttagaaacac cagccaattc gccaatttct
    18061 tttatagtta tactcaagaa gttcaccccc aaaatttagg aaaccgtttt acttaaccgg
    18121 ttacctagat actatcacat ctttttttca tttgcaacca ttttatataa attttgatat
    18181 ttttcccttt tttcaaaata ttgcaactta taattcaatt ttaatattta aattaatctg
    18241 caaaaaaaaa ttaatatact tttataatta tctaaaagta tattaattaa tttaagcagt
    18301 atttattaaa attcaaatcc ttgctctata atcatttttt tatcattttc aatcccactt
    18361 ccaacagttg tcaaataatc accaacaatt gcagaattta ctcccccatt aaatccaact
    18421 ttgtcatatc cctttaatga tagccttcca ccagcatacc ttatgtacac attaggaatt
    18481 ataaacctaa atactgctgt tgtttttagt atttccattg gttctaatac atcataattt
    18541 tccattggtg tattcttaat aggatttaaa atgtttattg gaaatgattt tacatttaat
    18601 tctcgtattt caaaagccat ttttagtctc tgttcttcac tctcattcat tccaattata
    18661 ccgcctacac atacatctag cccagctttt ttagcatctt ttatagtttt tatcctatct
    18721 ttatatgtgt gtgttgtaca tatattatga aaattatctc tacacgtctc aacattgtgg
    18781 tgatatgtag tcacacctgc tgacttcaac attttagctt gctcataatc tataatacct
    18841 aaagatgcac ataattttaa attagtattt tccctcaatc cttcatagat atttaaaata
    18901 ttattaaact cctttcctga cataccttta ccacttgtaa ccaatgagaa tctatgcact
    18961 cctttactct ccatctcttt agctctattt aagatttcat tgtaatctaa taatgaatat
    19021 tcttctacac cagttttata ataagaagac tgagcacaaa atttacagtc ttcactacat
    19081 ttgccagatt tagcattcat tatcgtacat aaatctgctt ttcttcccat aaaatattct
    19141 cttatttcat ttgcagattt taatagaata tcaaaatcgt ttttattatt tgtatcaagg
    19201 cttattaaat taagagcttc ttcataactt atttcttttt ctctcaatac tttatttttt
    19261 aattttatta tgtatttttc catatatcct cctatttgtc aacttaatat ttttatgtag
    19321 tttacttatt atatatagta ttgcatatat aacatttatt ggtcaacttt attttagaca
    19381 caagtttact atacacaaaa aaatactgct tcaaaacaat attagtatat agattataca
    19441 tattattatt aaagcagtat tttttattag aatataattc ttactggttt ataaaactat
    19501 ccttgtctta actccatcca agctttccat tgtaataact tctaagcctt catattctct
    19561 aaatagccat tttaaatcct tcatggcttg attaacctga ctttttgtta gattatttat
    19621 aaaatattct tttctagttt cctcatactc tttgctagtc aaaaagtttc ttagaaaatt
    19681 aaacgcaaat acacttggaa tattgtttac attagccttc ttgctgtttt ccttctcata
    19741 gtaaattttc ataaatgcat actcctttga tacttttaga tttctcttac aataattata
    19801 tgcatttaag tgctactatt cttataattt tattaattca tattctttac ttcccatacc
    19861 catttcacat gcatagtcta ttattctagt tccatttaca tgaggatgtt catgtttgaa
    19921 aacatcatga cccatttcct tgcaaatcaa atcatagcat gcttgttcaa tagctacagg
    19981 gtctgttgat gctaatattc ctatatcatg ggcaattggt ctacctgacc aaggtacaca
    20041 atcacaaagt ggagttacat tcataacaaa agttatatac cctaccttgt cttttttatt
    20101 tgatactgct ccataagcgt attctgccat cttttcgaca aacacatctg agtcactttc
    20161 ccattgtata gttactgctc tagttggaca gacagttgga cattctccac atccataaca
    20221 tacatcagaa tctataactg cttttttatc cactatactt atagcttttg taggacaaga
    20281 attaacacac tttccacaac ctacacactt cttttccttt actactggag taacatcaga
    20341 atgttgcatt tgttttcctg ctgcacttgc acatcccata gctaagtttt ttaatgctcc
    20401 tccaaaacct gctgcttcat gacctttaaa atgactcatt actatcattg cagaagaatt
    20461 ataaatttct ccacctattt ttacactttc aaaatgtttt ttgtctattt ttacattctc
    20521 ataatttcta ctatataatc catctgcaat tattactggt gcatttacaa ctgcataagc
    20581 aaatccattt tctatagcag ttgtaagatg gtctacagaa tttgttctac tccctgtata
    20641 cagtgtattt gtatctgtta aaaatggctt tccttcgcag tctttaacct tatcaaccac
    20701 ttgtctaact gccacaggac tcatatatgt agtatttccc ttttctccaa agtgaagttt
    20761 aattgcgact tggtcatttt tttctattaa atctttgaat cctgcttcat caaataatct
    20821 tcttacattg tttggtacgt ttttattttg cgaatttgag tataaatcac aaaaatatac
    20881 ttttgacttt tccatatcta caccccttta aaatatttac ttatactaat tttatcactt
    20941 ttaaagtaat ttttagtata ttttaacata attaaatatt cttatattta tttgatacaa
    21001 ataatattat ttgtattatt ttctacactt aattctatat attaaaaatc aaaaagactt
    21061 gaaacttaag tccaagtctt tttgattttt aggtgtagtt tttaacaaca taagattact
    21121 ttaccttgtg ataaaggtat tattaaactg gttttttatt aaataaaata acagctgcta
    21181 gtaaacatac tacagaaata agaactgtta taataattgg aataataaat tctggcattg
    21241 ccactttccc tgaaatcaag tctatatttt ttgacatcaa gaaattagga gtataaggtg
    21301 caatctgttt aggaatagaa attaaactca ataaaagagt tgccaccaat acaagtaaaa
    21361 cactggcaaa tgctggtcta aatagtacac acccaagaat taatacacta atatacataa
    21421 ttcctataag ccataaatta aatgctgaaa atataatatg attaagattt gcagttggcc
    21481 aaaaatacat tgtatatcca taagcaaata aaaaactcaa ccaaaaacca attgtcataa
    21541 taatcaccgt aacagagaat ttagacaata ctatagatga acgtgataaa cctttagtca
    21601 gcataataac aagtgtccct ttagaatatt catttgataa aatattacaa aaaataatta
    21661 gagttaaact cataccaaga ccagagatat tgctaaaaaa ttgtgtccaa gaatctaaag
    21721 cagttggtgc agcagtaact tttaaagtcg gtgcaaaatg agcaatcaag tctggcataa
    21781 attttgcaga aataggacta cttataccaa atattagaaa taaaataatt aaactaaata
    21841 atttataatt tcttaaattc tctttaaatt ctttttttgt aaatgctatg tattctctca
    21901 ctttactacc tccaaaaata aattttcaag tgataattct attagttcca tctttactgg
    21961 acaaagattc atttctgcga gtgtagatat aactgttttt tgtattgctt ttatatcttt
    22021 accatgcaaa acaatttcca tattagtttc ttctgaatct tttagtaagg atttaatacc
    22081 atcactagac ttaaactttt gaatttcatc attacttgca aactccagta aaagtctatc
    22141 ctttccgtgc atacttttta tttctgaaag tgtaccacta agggcaatgc ttcctttgtt
    22201 taatatagca acatggtcac agattctttc aacatctgat agtatatgtg ttgaaaatat
    22261 tacagttgtt gagtctttga ttttaagcat aatatctaat atttcttttc gaccaacagg
    22321 gtcaagtgca cttgttggtt catcacaaat aagtaatttg gggcgtgaaa gcaaagcttg
    22381 agctatacca agtcgttgct tcattccacg agaaaaccca cctattcgtc tcttttcatt
    22441 tctaagaccc acaagtgata acaactcttc actccttatc tgtatttctt tttttgaaag
    22501 tcccgtaatt tcaccacaaa gagaaagata ttcaagtggt ctcatataat tgtaaaactc
    22561 tggaacatca ggcagataac ctacatgacg attagaactt gttttcccat aggtcacttt
    22621 ctcaccacaa acatctatag ttccactatc tggtttaagt aacccaagta ccattttcat
    22681 tgttgtagtc ttacctgcac cattcttacc tacaaaccca aagactgacc cttctggtac
    22741 agtaaaattt aaattatcta ttatctttcg attaccaaaa ccttttgata atccatttat
    22801 tgagacaata ttcatcattc ttcacctctt cctattgtaa aatacaaaat tggtcctatt
    22861 aaactaataa acagtactac aataatccat attgccttat ttccaatttt ataatttgga
    22921 tgtctcaaca catgaacaag tgcagtaatt ataagtatta aatctaaaat aataacagga
    22981 accaaaagtg gtaagtattc catcaaattt tccataatct tattcctcca ataaagataa
    23041 tttttctata agaaatttgt attctttgtt ttcacttaat acagaaaaca ttggattatt
    23101 tttaatagca gcaacaatac ctgcttttac gattgtatca tcacgtgtaa tacctgttcc
    23161 aatttcagaa atccatctgt caagtttatt aaaaaagtca tccccatgta ttataattgg
    23221 gtatatatca cgtgttgcta aatctacata ttttcgtaat gatttaatag ctccttcatt
    23281 atcaccatgt attaaattaa tttgtgcctg tgttaaatat gaagaaagca taatagcagg
    23341 agataatgta tcaagctcaa atatatctga aattgctaga atacgtcttt ctatttcctt
    23401 catttgtaat ttatctgcat tttgcaaaat acccactagg ttttggacta atgatataag
    23461 gttctgatat gcaccaagtt gaaatgtttc tcttgcttca tccatttggc cattcatcat
    23521 ttgcccctgt gcaagaagta tagattcatt tatcatggga aaattgctgt tttgcaataa
    23581 atcaatcact tgtatgggtt gatttaacaa tatataacaa gttgcctcca tactttttgc
    23641 ttgacggcaa atatctatgt cattacaagt ttcctgtata cgaataaata tttctaatgc
    23701 ttcactaatt aatagttcac gctttttttc atctacaata tcatagtgat taactattaa
    23761 aagacccatc cgaaaaatca aaggaaaaca tgaataatat ttttttatga tttctcttat
    23821 ttcatccatg acttcatcaa atggtttaac cgtaaagtct ttgcacagtt tattatacag
    23881 tttattaata tcttccttca tcatttgagg ttcataacat attaactcat caacggtaat
    23941 gttgaaatat gtcgcgagtt gcggtaaaaa ggttatgtca ggatagcttt gtccagtttc
    24001 ccatttagat acagaagctt tagaaacgcc tatataattt gcaagttcat cttgtgtaat
    24061 tcctttttct ttacgcttta aaatcagcgt ttttgcgatg tttaattcat tcatgtcaat
    24121 ccctccttat gtataattat atccttaaac atgtaaagct aacaagcgat ttgaagttga
    24181 cttttgacga aaaaatcaac cacagagaaa caaataaaca agtatataaa atatatattt
    24241 aaatttatct ttaatctctt ttgtaaaata tgtaaacttt gtaaataaaa tccatattat
    24301 ataaaactaa tagttaatct atctaaatac agtttttatt tatcacgttt ttaaatattt
    24361 tgtgtaaaac ctcttttaat ataaacacct tattttcatt tctcatttca tattcttttt
    24421 aaaatactga atataactct tcgattttcc atttaattct tttataaagt tattattcgt
    24481 atttattcct ctaattataa caggcaacta tcatgtattg gtatttgtct attatataaa
    24541 aatctataaa agaaaagcag tcaatcattt agattaactg cttgtacata tatcttatta
    24601 aactgtataa actataattt ttattattct ccattttcat cccaagtcat aaatccccat
    24661 ccactatctg gataagtatc aatagacttt tctctaatca tataaccaac tttataacac
    24721 tcttttgtta ttttattaga tagtatacat ccttctccat ttatctaatt ccatttaatt
    24781 aacttttctt ttcaacctta acttttttaa aatcatcttt tttaataatt tcatacttat
    24841 tttctcttca acatcatcaa atgagggtgt ctcaaaatta actttttact tcataaggca
    24901 ctcttttttg tatgaagtaa aatatatttt catcatttca acaataagta agaggcttat
    24961 ctctattttg agacagcccc atttgatggt gttgaacatt taaataaggt tgaactcgtt
    25021 ttatctctct ttttaagata tctgtaaatt tgcacataaa gtctcttctt cttttacaat
    25081 tctaatagtt ttattaaagc caaagtatat atctccatat tctttcgtat atgatttatt
    25141 ggtactcttt catctactcc atgaccacca gttttatacg ctaagaactt aggtccaaac
    25201 gccaccatat ctttaaacca acttgcatat gtgccaccac ccatagcaat tgtatatcca
    25261 ttttcatctg ttacttcttc ataggcttct aataattttt taagtactaa attactctca
    25321 tccacataat gtaagtcttt atgagcaata acctctattt tccaaccatt acaaaaaacc
    25381 tttttgaatc tatctattat gttatttaaa actatatttt taccatacct tatatctaac
    25441 tcacatacga ttttttcctc atttactttt aatattccta aatttaaggt agtgtttttg
    25501 aatacctcat catattgatt aatccccaat gcatctccat aataatcact acaaaggtat
    25561 tttgaaacta attctatatc ttctctatgc tgaaaatcca tattatcctc aactatcttt
    25621 attaccattt tagatatagc attttctccc ttttcaggat tacttgcatg tacagctact
    25681 cctttagtag ttaactctga aataattcca ttaataattt ttgcagtaca atgagatgga
    25741 acaacatttt ctttagttcc tccccttact attatgtaag gtttactttt gtcaatttta
    25801 atttcttttt ctatccttat atgaaccctt cctttttctc cattaaccac tggatacata
    25861 gcatctggag taaatcccat acttggaatt tcttcacctt tatctaagta atatttgata
    25921 catttcatac ctgtctcctc atttgtacca aaaattaatc ttattctttt attaattgta
    25981 ggatacatat cctctatgtt tttcaataca tgtataagca tagatacagc acccttatta
    26041 tctatgacac ctcttccata aataatattg tcaattactg ctcccgaaaa tgggtctaca
    26101 ctccacccct ctcctggtgg aactatatct aaatgcattg gaatccctat taattcctct
    26161 ccctctccaa tttctgcata tccaatataa ttatcaatat ttttaacact aaaacctaaa
    26221 ctagcacagt aatctaaagt tttatctaaa gattttttag gtcctatacc aaaaggacat
    26281 tgtgaaatag gttcaccttg ttgtgaatca atttttatca attcttttag aaattctatg
    26341 gttctattta aactattatc tacacttctg cttatatcca taaatcaacc tactttctat
    26401 ctttttaaag cctgtcctta aagaacaggc ttttagcatt aaaaattatt tttttgtaaa
    26461 tactaattca caaacttcat catcatgagc acatttttga gcaaaatcta atttaacacc
    26521 ttgtgcgcag tcaactcttc cataatcccc ataacaagct aatctacaaa tttcttttct
    26581 ttcttcttta gttaatccat attctttcca agcagcatct aatggacagt gatggaattt
    26641 taaaacgcca ttctcatctg tattttctac taattccatt tcaaacactt tttgtccttt
    26701 actgttatat aacatttctg ccatttttcc tggagtatct gctacgttat atttttgacc
    26761 tctcatttta ccaaatccat atattgcttc tttacatata tcatctggat tagctcctaa
    26821 tttttcagct tctttcataa gaagatagaa ccatactgct ctttctcctg ttgctcctct
    26881 aattccttct aaatattcct tttctgtata cattttttct gacatttctt tctcctccta
    26941 aaattaaatt ctatatttta atcactgtga attagaatat tccaatgaat gaccctacca
    27001 atgctaatac aactaaaatt actaataact tagttattgt ccacttcttg tatttcattc
    27061 cccaatatac gaagaataca acaccaagtg gtaataaacc tggagcaatc atatttaatg
    27121 tatcttgaac aacaattgct ttaccaccaa tatcaaatga tagcggagtt gaaagcttaa
    27181 ctgtagttgc agataatgct cccatcataa acattcctag aattgaagca ccatcaatta
    27241 tcttattgac aataccacct gatagaattt tcttaattga atctctacct aaagaatatc
    27301 ctaaatgaaa taagtaataa ccttcgcaaa atagtaatat actaaacatt attgggaaaa
    27361 atgcacctat aacacttcct tctgctccaa atgaagcacc taaagctaag aatattgttt
    27421 gaaatgtacc aaaatctaaa gtatctccaa ttccagccaa aggtcccata agaccattct
    27481 taacacctga aataacttct cctgggattt ttccttcagt agctttctct tcttccatag
    27541 ctaaaactgt accgtgaatt aatcctcccc atatagcttg agtattaaaa aattgtaagt
    27601 gtctctttaa cgcatctact aaatcttctt ttctcttata taacttttct aaagccggag
    27661 tgaaacttgc acaaactgct aatgcttgca ttctttcaaa agagttggat aattctgctg
    27721 tccaccacca tcttagatat gtttttgtta catctttctt tgtaagtact cttgtcttat
    27781 taacttcagt tggaccttgt ccatttttaa cttctttatt ttttatttct tgcattatac
    27841 ttcacctacc cttttgtctt ctttcataaa ggtaattaaa agagctatac aaacaccaaa
    27901 tattgcagct gcagtaattg atatttcaaa atattgaacc ataaaaaatc ctataataaa
    27961 cattggtaaa aatttatttt tacctatagt aaatattgtt gttgcaaaac ctaatgcagg
    28021 taatataccg cccattactg ttaatccatt cattaaccat tgtggtataa catctaataa
    28081 tgattgaact aaatctgctc caaaaaagtt acatacaaaa actattggaa accttaaaac
    28141 aaacccaaat attaaagaat aaagtgttgc acatctccag atgccttttg tattaccttc
    28201 ttcagcatac ttatctgcct tatgaaccaa tacagcatta ccagttcttc ttaagttatt
    28261 aactaatact cctataacac ctaaaggtac cgcaatagat actgcaactt ctgcattaac
    28321 accagtttga agtgctactg gtattgcaat aagagcagct agacatttat ctgatggaat
    28381 atttccccct gctgcgacca ttcctagata aaccatttct atacttgcac caacaatcat
    28441 accagttgtt acatcacccc aaagtaatcc aaggctaaaa cctataaata aaggagactt
    28501 tagtgttgag aaaagggtat accctgcaag acctgctgca aaccaatacc ataatcctgt
    28561 tacaattgcc aacatcaaaa cagattccat ttataattcc tcctaattta tattttttat
    28621 ttaaatttct ttaacgcatt ttcatatgtc atagatgatt cctctggtat aacttgtagg
    28681 actatttcaa ccccattttc attaagttca ttaagttgtt ctacatcctc atttcctaat
    28741 gaaacagctg taaacaccat tttctttcct gcttcatttg gaatacctcc taattgaatc
    28801 ttttcatatt taagtccagc tttataagcc ttatttgcca tatcaacatt tttaaataga
    28861 ataaatatat ttttatctcc taaagtgttg ttttggaatg cttgtcccgc atcttctgct
    28921 gttaaaataa ctacttctac tcctgatggt gctgccattt tatatatgtc agccataaat
    28981 tcatcttgac ctaagaagtc atcaactatt attatttttt gagcttgagc gatttttacc
    29041 cattttgtta taacttgccc atgaattaat ctgtggtcta ctcttactaa tgttattttt
    29101 gccattatat tcacctcata atttatattt ttttaaattc tttaattaaa tccacacaaa
    29161 ggttattatt ttttttgacg attctttctg gtaatgtatg taatttatct tctttgctta
    29221 attcttcatc tacgattaaa attgtctgta agctaagtcc atttattgca tctattcctc
    29281 ttcttatagc aacagctatt gcaacacttg atgtagatcc tccatataaa tctgatatta
    29341 taattttcac atcttcttta tctactactt cttcaacctc tttcataaat acagaaacat
    29401 ctttttcaga acttagtgat aaaacttcat attgatttga caatccaaag tttttatttg
    29461 tttcttctac taagactttt ccccaagttc catggcacag tatgattacc ttatatttat
    29521 tcattgctaa ataaactctc ctttatagcg attaatattt tggtttaatt ctacttcttc
    29581 ttcatcaggt accatttgaa ttgatacatt aatattcttt ttaataaatt catctattaa
    29641 aagaaactct tttttattaa tgtatacatt ttgagatatt ttcttttttc ctattcctgt
    29701 aggtattctt ccaacaataa gttttttgat attaatccct tcttctatca ttctatttgc
    29761 agtatctaaa tttttaatta atacaaaaac gttatcatca gcttgattat tataaaaata
    29821 tctccttgat tcacttacag ttaatattga taaatcaata ttctttggtg ctgccatttt
    29881 tatcaaacct ttagcaataa catcattggt tgtttcatca tctactacta ctatcttttt
    29941 tacacctaga tgcttaaccc atttatatat aacttgacca tgtattaatc tatcatcaca
    30001 tctgcaatat tttactaaag acatttttaa tcaaactcct ttttctatta cattgagcta
    30061 agaactttat taatattgtt tataccagtt tgtcctgctt caatacatgc ttctgctaac
    30121 tcttctaaac tttttccctc tctattaatt aaagcttcaa gtagcattgg aagatttact
    30181 ccagtaagtg catgaaactt gccacctttt ttaaggttta aacttgcaac attacttggc
    30241 gaacctccta ataggtcagc taatactaaa actccgtcac cttcatctaa ttcatttaac
    30301 ttttctacaa aatttttatt taagtcttca atattatcat tcctatttag tttaattgct
    30361 gctgttcttt ctgctggtcc tgcaataagt tcacagcttt ttataatttc ttcactaaaa
    30421 ctcccatgag tcataactat tattcctatc accaatttca cctcactttt cttgtcactt
    30481 tttatataag caattgccgt gccaacttat gtgtatcaat aacaaatggc tattttacag
    30541 gatttaatca aaacttttta ctcaattttt tttaaaaact tattatttcg atatgtatca
    30601 aaagattttt tcaacctgta tcaaatctgt atcaaaaaaa gtaaaaaaaa gatagccttt
    30661 tggctatttt taaattttgt atcaactttt gaatttatct gtatcatatt gtgattcaaa
    30721 tatatctaat atatttgcat attccatatc tgaaataatt atatcgaatg tctcttctac
    30781 tagcttaaaa ctttctttta taactaaata taattcttta tttctactaa ttctttcttc
    30841 atatgattta taaactaaag actcttttat tattactctt tcaatcatac atgaacaatg
    30901 aaatataaac tttactaaaa gttcatcttg aattactaaa gaatagtgtt cactaattct
    30961 attaattact tcttttaata taaaataagc cttttcccca tttaaaaaag tcaaagtttt
    31021 actaatatta tcaattagta atctatcaaa atatctacca ccattatctt tttcagcata
    31081 tgtaacttcc atatctccat aatgtttctt tatagattct ataatattaa aatataattt
    31141 ctctaatgtc atttctggag ttagagcctt tctagttgct tctattacaa taggtgtact
    31201 taccatatct attgctttta cttcttttcc tgtagcatca cgaataactt tagcaaatgt
    31261 taaaatagac cccatatcag ttaaaattaa aattcctttt cctttatcaa ttttattggc
    31321 tatttctaca gcttgtacta aaatatcctg aactctatct tctaatccca tattaattgc
    31381 cactgcatgg ttacaatcca gtaaagtatt ggctacattc accatgctag atgctgtaga
    31441 ttcaccatgc attatgacta atattgctat actctcctca tttaatccca catacgataa
    31501 ataaagaaat gttgctaaaa aaattgcttc atcttctgga aactctactc catacattaa
    31561 tgacatgtta gataatattt cttttgctat gttatattca tatgctcttt ccttcataat
    31621 ttcatcttta ttaggatgct ttactatatt tccaatcttt attctttcaa ttaaattctg
    31681 aatatgtaaa gctatagctt ttattaattt atctaatcct tctcttttgc tccatttatc
    31741 atgcttttgt aaaatatatt ttacagtagt tgcaattgaa tcattaacaa tgttgttata
    31801 agctgtttga ttactactat tatatataaa agtattcatt aaattatagg aatacttctg
    31861 tatgtctcca tctataacac ttctaatttg tgactcttta ataccttctt gttgaagttt
    31921 attccaagtt tcttttatca ttccataaaa atctaaatca tattttttat tttctattaa
    31981 taaattttca ctttcaaaat ccttttcttc tggtaaaaaa ataatatcat cttttccaat
    32041 aaaactgaaa ttttgtacaa actcctcttt tctattattt ccatataatg attctctaat
    32101 attatttggt agaagagaga gccttacata tacacattcc cttttatagg tcatataatc
    32161 taaaaaagct cttgcacaaa ttaattgtat atcgcttttt aattggccta tatttccctt
    32221 acacttatat aaaataaatg ccttaataac ttcttttgaa acctttaact taacaccaat
    32281 cctaacactc tcttctttaa aaaaataaca tataagcttc attctctctt gaaagcctct
    32341 ttcctctaaa gacggaatct ttatagttac aggtattctt cttaaaaacg tttccaacat
    32401 tgctgtttct gggtcttctg tagtggctgc aattatcata actctacact cgtgtacctt
    32461 attagcctct cctaaccttc tatatatccc tttatccata agcagaaata gcatttcttg
    32521 tccctctgca gataatctat gaacttcatc taaaaacaat actccattat tagcttcatg
    32581 tacaatacca tacttatctt tatcagctcc agtaaatgct ccttttacat atccaaaaag
    32641 ctgcgctaat aataattgct gattatcaga ataatcagca cagttaaata tgataaatgg
    32701 tgcattatca ctatcttctt ttatagttaa actatactta tacatatatt ctgcaaatat
    32761 agatttacca actcctgtag gtcctattat taatgtactc aaccccttag gtggatatat
    32821 tactgctgct ttagcctgtt ctatttggga ccttaaactt ccatcacatc ctactaaatt
    32881 aaaaatattg ttctcttttt ttatactctc taaaatatac tcatctttga tagaatcatt
    32941 ttcactatat tcgtttatag agttaatatt atcaaatatc cctttattta gtttctttcc
    33001 taaaatactc tcaatacttt ctttatataa gtactgaaca ggcttaccct ttatctttat
    33061 aataatactt tcttttatta attgatttaa ttccttacta gcattacttc tatttatacc
    33121 tacttcagta gctatatatt ctgcatcaaa tccaaatcta atgccattat taaagttcaa
    33181 gtgttcttct gttaaccttt tcaagcaaat taaaactttt tctttccttg atagcttctt
    33241 ttgtgtcata gttaacctcc cctataagca gtaatactgt taaacattta ttattaagct
    33301 taattctaca atattttaat atttttgtct aattatgtaa ctattgattt tctttcctat
    33361 tcgttttata atataaatta cgttaccctc atcttttata gaggaggaat ttatatgaat
    33421 tttttatcag atttacacac acactctata gtcagtggtc atggctatag cactttacta
    33481 gaaaatatta attattgtaa agaaaatgga attaagatac taggtacatc tgaacatggt
    33541 cctaagatgc ctggttctcc ccacaaatgg tactttcaca acattcaaaa tatcccaaga
    33601 atcataaata acattataat tttaagaggc tgtgaagcaa atatactaga tattaaagga
    33661 aacatagacc tagagccttt tgtaattcct cggttagatt atcttatctt gtcatttcac
    33721 gaagctgtgt tttctccaaa tacattagag aataatacta aagctttaat aaatgcaata
    33781 aataagcatg ataatattga aatattagga caccttggaa acccaaacta cccaatcgac
    33841 tatgaattaa tcattaaatt agctatagaa aagaatatct taatagaaat aaataattgt
    33901 tctattaaag gcgtgtcaag aaatggtagc tcggataact gtaagtatat tgctacactt
    33961 tgcaaaaaat atggtgctaa aatcatactg acttcagatg ctcacatttg ttttgacata
    34021 ggtaactatg agtattctga aaatatctta aaggaaatta attttccaga tgaattaata
    34081 atgaattatc ctaaaaaact tattaatcat tttcaccaaa aaggtaaatt actagatgtt
    34141 gattatacaa atatctaagt aataatacat gcttacttta actcccataa aaattttaat
    34201 actatttata ttatatgaaa taaagaaatt ataataaaga agctatttaa taaagcttaa
    34261 ttacttttat gaacttgatg gattgatatg gtctatgata gcaatagaaa ttataacatt
    34321 tttaataaac ttagttttat ataccttata gtataaatct aaaaaagcat catctaaaaa
    34381 ggagctgtca catgagcaaa ttaaatttgt tctatgatag ctcttttttt acttatttta
    34441 attaggtata tttttaatta ttttatataa agcttatgtt ctaag
//
LOCUS       DAFAZV010000046        33407 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFAZV010000046 DAFAZV010000000
VERSION     DAFAZV010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 33407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33407
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.046"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..765
                     /locus_tag="KOU88_002996"
     CDS             <1..765
                     /locus_tag="KOU88_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3212854.1"
                     /translation="FMIREIGYLDDENNLIAISKYKECYKPSIEQGAVVDMKVKTVLI
                     VSNVNNIELKIDPTIIFATLKDIQDLETKIGTVNTKIDTTKTELTSNIETTKTELNTR
                     IDTENEKQNIKIDQLIAGGSNVASTQTITIDDWVEDAENGFKATVTHSLLTQRIVVNI
                     IDATTKENVVTNFKIIDDNSIEIRSETRSELNVYVINGNAETHFINATVDDNRVSEMT
                     TYSSKKIHEEISKVAEQLTGINSNIISTVNNNLIPM"
     gene            782..1852
                     /locus_tag="KOU88_002997"
                     /pseudo
     CDS             782..1852
                     /locus_tag="KOU88_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903579.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2241..2588
                     /locus_tag="KOU88_002998"
     CDS             2241..2588
                     /locus_tag="KOU88_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212855.1"
                     /translation="MNRKNRIIYDQLGNIWLQTGEAMGDIQEWSEITELNFLDVEFGS
                     IDYSKQYIESINPVTKEPVIKDIEVVLTDEQKRLEALEKELNILKEGNKDRDSEIVNT
                     AFEVENIRLNNNI"
     gene            2600..2770
                     /locus_tag="KOU88_002999"
     CDS             2600..2770
                     /locus_tag="KOU88_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212856.1"
                     /translation="MYNLLKLMIEQKNYSTKEDLQHKMDVFYAVNRITEEQYLELTNL
                     LKKEEIPAEPTV"
     gene            2839..3270
                     /locus_tag="KOU88_003000"
     CDS             2839..3270
                     /locus_tag="KOU88_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK3212857.1"
                     /translation="MNVTIVFLATNIFIKLVILAIAFDTLLGCLRAIKTHQFNSSFGI
                     NGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDFLRLNHLGISEFFSILFILYE
                     SVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNIKGGSK"
     gene            3270..4082
                     /locus_tag="KOU88_003001"
     CDS             3270..4082
                     /locus_tag="KOU88_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3212858.1"
                     /translation="MKICITVGHSILKNGSCTSADGVVNEYKYNKSLAPVLADTFRKE
                     GHKADVIICPEKQFKTKNEEKSYKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRICDKLGTVFKNRGAKLDKSLYILNSSKPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEIDKIPATVVGWGYNDGKILICD
                     IKDYVPGQTENLYVIGGGACEKIGSITKERYTMIKGNDRFDTLYKALDFINR"
     gene            4413..5594
                     /locus_tag="KOU88_003002"
     CDS             4413..5594
                     /locus_tag="KOU88_003002"
                     /inference="COORDINATES: protein motif:HMM:NF014516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3212859.1"
                     /translation="MKIEKIEIKGIGGIKELSLRFNKGLNIICGANGIGKTTILEVIS
                     HLFSIQSSDLKKNAKFDLGEAIADYSFEDIEAVHKSTYQINDFNASVKELIFDNRDKK
                     KYSKFVLFFKTHRELNYSKLDGITGDETYSDDSTSYMADLGIDSSKIKNWFINRLLFS
                     KQEGSLTKEQLCNLDLAIEMISILDKNVSYSRIVSDSLDLMINTPQGEIYIEYLSSGY
                     KSCFYILLGIIKELEYRFTKPYIEVKDFDGVILIDELDLHLHPEWQVKIVNALKVLLP
                     KAQIIATTHSPNMIQTLSPDEIIPLTMDENGNVRKKDLELGEYGLQGWTIEEILTDVM
                     GMKTTSSELYLDTMKKFDRAMDKENVDEIKKYYDILMKMLHPNSTLRTILKIQVAGII
                     D"
     gene            5591..6349
                     /locus_tag="KOU88_003003"
     CDS             5591..6349
                     /locus_tag="KOU88_003003"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212860.1"
                     /translation="MIKINRTRKPIELTEEVQKQLTEEFKNNKEKSVWRKKYITNALL
                     EMSHGKCCYCEMKLIEEGKSLNVEHFHHKDKYPDEVVKWENLLPSCGRCNSEKGTHDT
                     KLEPIINPAINNPKDYLYLYNYRYKSKNRNKLGSDTIDILYLNDTDKLIKPRVNICMA
                     LFKRLESIKTFVEDYQNGTGTHTRRKNKIINEVKGVLRCAQPTEEYSAIVANVIVNDD
                     DYKYIKEIMSEFNLWDNELEELESKAKEIMLDSE"
     gene            complement(6422..6910)
                     /locus_tag="KOU88_003004"
     CDS             complement(6422..6910)
                     /locus_tag="KOU88_003004"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212861.1"
                     /translation="MSLKYWFKNIKKKKQIKKDIKYFKGNKESVINYQEYYTKIYNHY
                     NEIKNINTIRKIEIEQTRIKGQLEKNNNPGNALFFSLMAVVFSLLANLFLSSLNIKDN
                     YINLILQSSSIIVLIFIAINTSLDIAVPYRDEIQFYTTALDVLEDMKKKKLKERKYKK
                     RR"
     gene            complement(7245..7628)
                     /locus_tag="KOU88_003005"
     CDS             complement(7245..7628)
                     /locus_tag="KOU88_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212862.1"
                     /translation="MRKKLFLGIFIVLVIAAIVVLNIKNDKNIFIGESEHWTAKFVTT
                     EEQSELEIKYKDSKDVVKQKFNYSYEFIDGEDAIIILKDAVLESGQEKIIKRQRPGLY
                     SNRESNYKVIISWNKNEETINLKKK"
     gene            7776..8105
                     /locus_tag="KOU88_003006"
                     /pseudo
     CDS             7776..8105
                     /locus_tag="KOU88_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433383.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8304..8519
                     /locus_tag="KOU88_003007"
     CDS             8304..8519
                     /locus_tag="KOU88_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212863.1"
                     /translation="MYINQTGFVSNGLGIKQQQRKDPTSNSFSYNAPSSWKPVGRDSL
                     QYNCGFESIATLVRGGSSWSFNFIVQP"
     gene            8866..10032
                     /locus_tag="KOU88_003008"
     CDS             8866..10032
                     /locus_tag="KOU88_003008"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212864.1"
                     /translation="MLLGDEIKLNLEPSDLINSIPYFKSEYSDLCGLDADFIKEQLLK
                     AENNDRIVSMARGEGRAFVVEPIIKRNNYCKFRNNSYDIFNSIPSYEYAIKIIERYKN
                     HIFNPTEYRNSVMRRVGTYENDIFNWGYKSMHSYMESLPLREFLEPNKVDRTLLFEFL
                     DFMRELFSYQLRTYPGRFDNSKTLDAIETIKNAIIKTESHDDLLIIKEWLCFLLHTGN
                     HRVFKNITPWISLSTGSKRYNIVHKFASRKPFTSYRTISEKHTYNEKEKFIFIDYWEY
                     VDKENLTFRNTNYIVNKLKSMGVNWYENRNNEVMVKYALFPQQIIGYYYFENRKLQYY
                     FINPHYLKAWQKNKDFKIGDELYINQEQVVFPFNNPYRVIYGKKYGHISVVDKR"
     gene            10251..10640
                     /locus_tag="KOU88_003009"
     CDS             10251..10640
                     /locus_tag="KOU88_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3212865.1"
                     /translation="MKINKLPHAELKLMKYIWGVDDVLASRDIIEVMKLKYDWKKSTT
                     LTFLKNLVDKGFLTTDKVDRCTHYTIAIKEKDYLKVETKSFFSFMHNNSFKSFISALH
                     DDEVLDSKSLDKLEEYFKNLKEEDIDD"
     gene            10960..11469
                     /gene="vanZ1"
                     /locus_tag="KOU88_003010"
     CDS             10960..11469
                     /gene="vanZ1"
                     /locus_tag="KOU88_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ1"
                     /protein_id="HBK3212866.1"
                     /translation="MKSRKHNITKGLFIVYIIILTWIILFKLQFDISSLETMNLRSIN
                     LVPFAGSLIINNRVDISEIILNVVIFVPFGIYVCMLKEEWSFIKKVIPIFITSLAFET
                     LQYIFALGASDITDLIGNTLGGIIGIAVFMLLSKIFKNNTIKIINVLALIVTIIVVLF
                     LGLVIFANL"
     gene            complement(11571..11765)
                     /locus_tag="KOU88_003011"
     CDS             complement(11571..11765)
                     /locus_tag="KOU88_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase"
                     /protein_id="HBK3212867.1"
                     /translation="MSVIVMCSRCGKEIDKYRNKYITYYEKNTNAEIKVCINCALDLL
                     EKTRENQELNIQEFQDTIIL"
     gene            complement(12281..12673)
                     /locus_tag="KOU88_003012"
     CDS             complement(12281..12673)
                     /locus_tag="KOU88_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3212868.1"
                     /translation="MAALKSFEKPLTPEEEIEYLTKFKIENDKSAKDTLIERNMRLVA
                     YIAKKYNNSTEDQDDLISIGTIGLIKAIETYNIDKGTRLATYASRCIENEILMNIRSN
                     KKNKTQVSLQDPIGTDKEGNEINTTLYM"
     gene            13240..13602
                     /locus_tag="KOU88_003013"
     CDS             13240..13602
                     /locus_tag="KOU88_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212869.1"
                     /translation="MKIRKSGFISIECIISIAILYVAVYLVSTSLYNCYSFISRNISD
                     REMLSTAKKYIEDEKYRIQNSKYELIEDKIEKNYINGYEINSKIEQILDYYQCYEINI
                     EIKNEFKKLRFNSYVTRK"
     gene            13586..14302
                     /locus_tag="KOU88_003014"
     CDS             13586..14302
                     /locus_tag="KOU88_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212870.1"
                     /translation="MLLENKGSILIITLIIFSIISTVCIMCIGLIYTHNNMFELGYKD
                     IQLKEISLSGIEISVSNVLSCVEEAIDVSNNEDEFREYFLGNNMIECIKKIKDTSYSS
                     LEELSLKVENNTIYDRGDFFEFDIESNVREKEFLKAIKVRVKIKNPWIGIDIEDYMDK
                     SNNNKIDDKTFNNYKASENNEILNQFKNESENIRNQEVGGFTEEDEEYEEELKQNIIE
                     NIKKNFDEKNLVQVYKYRGV"
     gene            14322..14741
                     /locus_tag="KOU88_003015"
     CDS             14322..14741
                     /locus_tag="KOU88_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212871.1"
                     /translation="MTVIELIVSISIILLIVTLSFPKDNLENHKINLFARQLCSDIRY
                     VRRINMFSNYNTYIYYINQGKHEGYVLRKDGKNIKSIMLPKNAKIARSIEIIKFKSDG
                     SPQKASTIEIYNNRLRKTITITPVSGRVLLKEGKYET"
     gene            14731..15255
                     /locus_tag="KOU88_003016"
     CDS             14731..15255
                     /locus_tag="KOU88_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212872.1"
                     /translation="MKHKYGYLLLESVVSLSSMVIIILVLYSIFLSTINLKLKVEDKI
                     ELQQQSLEIIKSMEGIISNSMGIMNVSNYEETFKKTTSIKCRYLDENNNEEGISNKEI
                     ILNERRNKLFVNSLNGESSQAGGYEIGDYVDEMYVSITNNGQYVNIKLKLSKRSQKYE
                     TDFKIKVWNFSESI"
     gene            15567..16124
                     /gene="efp"
                     /locus_tag="KOU88_003017"
     CDS             15567..16124
                     /gene="efp"
                     /locus_tag="KOU88_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBK3212873.1"
                     /translation="MVSAGDFRKGVTFEKDGQPCLVVDFQHVKPGKGAAFVRTKYKNL
                     KTGAIREESFNPSEKFPKAVIDTRQMQYLYNDGELYYFMDQENFEQIPLNYEQVEDAI
                     KFLKENEVATIRFYQGQPFQVEAPNFAELEVTDTEPGIKGDTASNVTKAATVETGAVV
                     QVPLFINTGDKVKIDTRTGEYLSRV"
     gene            16216..16671
                     /locus_tag="KOU88_003018"
     CDS             16216..16671
                     /locus_tag="KOU88_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK3212874.1"
                     /translation="MKHLYEEVAYLKGLAEGLEISAESKEGKMIHKIVDALEVFADAI
                     VTLDEEQEELQDFVESIDEDLADLEEDIADMEEDLYEEDDDEDDEDFSYIEMECPNCG
                     ELVEIDEDLLYDDEVDVVCPDCKAVILSSEDDCDDDCTCGGCSSCDDRE"
     gene            16834..17544
                     /locus_tag="KOU88_003019"
     CDS             16834..17544
                     /locus_tag="KOU88_003019"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBK3212875.1"
                     /translation="MKISKKLLDNIQRFENVINYKFKNKEYILEALTHSSYSNENKKY
                     NFNERLEFLGDSVLGIVISDYLFNEEANLPEGELTKLRANIVCEDSLSEVANDINLGI
                     HMLLGRGEEATGGRHRTSILADAFEAVIAAIYLDGGFESARQFILHHMENIIYDSRKG
                     NIFRDYKTHLQEVLQGNGENNIWYRLIEEKGPDHNKRFVMEVGINDDVLGIGEGKSKK
                     EAEQLAAKIALKKKLWEK"
     gene            17598..18668
                     /locus_tag="KOU88_003020"
     CDS             17598..18668
                     /locus_tag="KOU88_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3212876.1"
                     /translation="MKKRIIPIFVPHKGCPHDCIFCNQKKITGVSTDVTSEDARNIIE
                     ECLETIDKDADVEIAFFGGSFTAIDIDIQKSLLSVAKEYVEKGLVKDIRMSTRPDCID
                     EDILSMLKEYKTSIIELGVQSLDEKVLLDSIRGHQSEIVYKSSKMIKNSGIKLGLQMM
                     IGLPADTEEKCIFTAKKFVELKPDCVRVYPTLVVKDTGLEKLMEQNKYNPFTLEESVN
                     IVKKVLVLFYVNNINVIRVGLQATDDIQIGKAVLAGPYHPAFRELVEADMIKDYLEFV
                     ILQNKNIKQMLVKSNKKNISKIIGNKKTNVKYMEEKFGVLLKTQESDLDINQLEIVLD
                     GKSLISANMRDIHRKLYDIYDL"
     gene            18696..22250
                     /gene="smc"
                     /locus_tag="KOU88_003021"
     CDS             18696..22250
                     /gene="smc"
                     /locus_tag="KOU88_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBK3212877.1"
                     /translation="MYLKRLELKGFKSFPVKTDIIFKEGITAIVGPNGSGKSNISDAV
                     RWVLGEQSIKSLRGDKLEDVIFAGTDTKKPMNYCEVALTIDNSENQLELDFTEVTIRR
                     RAYRNGESEFFLNNKSCRLKDIKEVFLDTGIGKDGYSIIEQGKVDEILSNNPLSRRKV
                     FDEACGISKYRYKKQEAERNLSNTKENLERIDDVYIEIENQLKPLFNQQTKAKKYLEI
                     SEKLKTLEVNSFIREIEGIEKELSEVNEHRKVIEKELNEKEEQKNVVEKKQEDINKEV
                     EVLQDVIEKSVDYINSIKGVISKKESQINLIKERIRNFTNEISRKNLEINDIKEKLNE
                     NKQYIKELESNKLSGSEELSTLQENIKVLEGSKDKQKIKLESLNNEIELLKESIIDIL
                     NKKQEFSNKLSTLNANKENMNIRDENINSEITELNKNIEIKSSELDTINKEFNMQNEN
                     LKNVNNRHKELSINLQDSISEHNKLEDEIQKSKYNLNGYNSKLNVYIDMENHYEGFNR
                     GVKEVLKNKNLKGVHGALGQIINVPEKYEKSIEAALGAYMQNIITDNEFSAKSAINYL
                     KQNNLGRVTFLPLNIIKSNKISLGNLKANTKFIGIASDLITFDEKYRNIIENILGRTI
                     LINNIDEGIKFAKETGHRFKIVTLDGEILNPGGSLTGGSLKTNGNILSRKRYINEYTE
                     KISNIKNEISHLELKRESLDKDVKNIKNEIDSHESKIKDLEKSIIIKSTSIKNVESEI
                     ESLKGSITKLENEKNDLNSNLNYTLEKSDDVRKDMEELDDLYNKNKEKIDALNEEIKR
                     YNDLYDKEKSEFDELNLSLVKKTEVYNSIVRDIKRISGENCELEEKNKQLEESLNYEE
                     HEIIKLQDSILTEEKEKENLTKQLGDSNRNLETRKIAKDDLKNSFDEINKELKTIDRQ
                     HIELKESLFKVGGRLERLKTSQDTYINKLFEQYDMTLVQALEIKDEDLDIDRKFLESL
                     KREIRSLGNINIDSIKEYEEIKERYDFYSEQKQDLEESMEEIEKLIHTLEENMKSEFE
                     IKFEEISKNFKYVYKRLFGGGCGELTILDKENLLESDILITAQPPGKKMKNLNLLSGG
                     EKALTAISILFAILITKPTPFCILDEIEAPLDDANIFRFGEFLKDLSKETQFISVTHR
                     RGTMEAADYIYGVTMQEKAISKVISLKLKEAQEITDII"
     gene            22277..23557
                     /gene="ftsY"
                     /locus_tag="KOU88_003022"
     CDS             22277..23557
                     /gene="ftsY"
                     /locus_tag="KOU88_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBK3212878.1"
                     /translation="MLKKLFGFGKDKEKEIEKKDAEEEIEVEDSVDNLENLEETIFSG
                     LEEEVIDKVEDVEEKNEESVNNEGTEEIENFEKIEVEMNSNGKEVENISNNDSQEEII
                     EELENYDEIESKEIEDKEDKKVNLFERLKQGLTKAKQGITDRIDEVLKSYTKIDEELL
                     EDLEEILITADVGVNTTMDIIERLRDKIKQKGITEPIKVREELKSIVEDILTNENSTL
                     DIEPAPCIILMVGVNGVGKTTTIGKLANRYKKDGKKVLLAAADTFRAAATEQLEIWAN
                     RTNVDIIKHQEGADPGAVVFDAIKAAKARKTDVLICDTAGRLHNKANLMNELGKVFKI
                     VDREFPEAKREVLLVVDATTGQNAVVQAKTFKEVADITGIVLTKLDGTAKGGVVLAVK
                     SEVDVPVKLIGVGESVEDLQDFNAKSFSDALFGN"
     gene            23660..24028
                     /locus_tag="KOU88_003023"
     CDS             23660..24028
                     /locus_tag="KOU88_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBK3212879.1"
                     /translation="MNIEKMVEIGLLFEQYKELLTDKQKEIVALYYEEDYSLGEISEN
                     LNVSRQGVYDTLKRSEKILRDYEEKLHLVSKIQEQEKNIKIIKDKIIDIKEDLLHNRD
                     CANLIPKLENIEDVCREMIK"
     gene            24025..25377
                     /gene="ffh"
                     /locus_tag="KOU88_003024"
     CDS             24025..25377
                     /gene="ffh"
                     /locus_tag="KOU88_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBK3212880.1"
                     /translation="MIFEGLSDKLQGAFSKLKSKGKLTEVDVKNAMREVKLALLEADV
                     NFKVVKDFIKKVQERCVGQEVMQSLTPAQHVIKIVNEELTSLMGDVQSKVMISSKPPT
                     ILMMVGLQGAGKTTTAGKLGGYFKKQGKKPLLVACDIYRPAAIKQLQVVGEKLDIPVF
                     NMGDKENPVNIAKAGLSHAIKNANDLVIIDTAGRLHIDEVLMDELKSIKSEVKPHEIL
                     LVVDSMTGQDAVNVAESFNEALGVDGVVLTKLDGDTRGGAALSIRAVTQKPIKFMGMG
                     EKLDDIEPFHPDRMASRILGMGDVLSLIEKAQENIDLEKAKELEQKIKKQELDFEDFL
                     QQMEQIQNMGPLDKILGMIPGMGNVKDQLGDVDLNGKEMKRTKAIIQSMTTYERRNPG
                     VLNASRKKRIAKGSGTSVQDVNRLIKQLNEMKKMMKMFAGSQKSMKKRGGLGGLPFFK
                     "
     gene            25415..25687
                     /gene="rpsP"
                     /locus_tag="KOU88_003025"
     CDS             25415..25687
                     /gene="rpsP"
                     /locus_tag="KOU88_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBK3212881.1"
                     /translation="MAVKIRLKRMGANKKPFYRIVVADSRAPRDGKFIEEIGYYNPIS
                     EPKQVRINDEKAIKWLATGAQPTEVVKKLLVKNGVIEKFEASKQAK"
     gene            25752..25979
                     /locus_tag="KOU88_003026"
     CDS             25752..25979
                     /locus_tag="KOU88_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBK3212882.1"
                     /translation="MKELVVDIAKALVDNPDSVVVEEFEDNDGIVLKLTVAQEDMGKV
                     IGKQGRIAKAIRTVVRSVANRENIKVSLEIV"
     gene            26087..26602
                     /gene="rimM"
                     /locus_tag="KOU88_003027"
     CDS             26087..26602
                     /gene="rimM"
                     /locus_tag="KOU88_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA processing protein RimM"
                     /protein_id="HBK3212883.1"
                     /translation="MKEKLTHFKVGQIVNTQGLKGEVRVYPLTDDIERFDELKDFYLG
                     KDLNNKLAVEKVRYKGSMVIMKIKGIDSIEKAEKLKNKFMYVSREDSRELEEGEFFIA
                     DMIGMEVLTVDGKYVGILEDVLQYSANDVYVVKGEEDKEFMIPAIKKFVPTIDIDERK
                     MIIDPIKGMID"
     gene            26611..27306
                     /gene="trmD"
                     /locus_tag="KOU88_003028"
     CDS             26611..27306
                     /gene="trmD"
                     /locus_tag="KOU88_003028"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBK3212884.1"
                     /translation="MRFHIMTLFPEIFNSYMDESIMKRAVEKGIIEVHIYNIRDFSNN
                     KHKKVDDYPFGGGAGMVMTPQPIYDTYKHIITTHNINNPSVIYLTPKGKVYNQSMAKQ
                     MSLKEDIILLCGHYEGIDERIIDLIVTDEISIGDYVLTGGELPALIMIDSISRLIPGV
                     LNQEESFEEESFKDNLLEYPHYTRPRDFEGLKVPEVLLSGNHKKIDEWRREESIRITK
                     ERRFDLYKKSNEK"
     gene            27491..27841
                     /gene="rplS"
                     /locus_tag="KOU88_003029"
     CDS             27491..27841
                     /gene="rplS"
                     /locus_tag="KOU88_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBK3212885.1"
                     /translation="MNEMLRAIEQEQLKNEVPNFGPGDTVKVHVRIIEGKRERIQVFE
                     GVVLKRQGGGARETFTVRKMSFNVGVERTFPVHSPKIEKIEVTRKGKVRRAKLNYLRG
                     RVGKAAKIKEARNK"
     gene            28162..29058
                     /gene="ylqF"
                     /locus_tag="KOU88_003030"
     CDS             28162..29058
                     /gene="ylqF"
                     /locus_tag="KOU88_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBK3212886.1"
                     /translation="MSNEYEEYLMNDNLHINWYPGHMKKTKELVKNNLKLIDVVIELL
                     DARIPFSSKNPDIDRLVGDKPRVVVLNKSDMADRDKLNQWIEYYKKINIKAIPVDTIK
                     GVGINKIIEECKNVTREKMSSLKDKGRKERAIRIMIVGVPNVGKSSLINKLTGRKSTQ
                     TGDKPGVTKGKQWVRLKGNLELLDTPGILWPKFEDQEVALNLAFSRAIKDEILDTETL
                     ALRLIEKLMKIEPEKLKARYKLDCLGETPIETMDMIGHKRGFITGKKELDYTRIATTV
                     LNEFRDGKIGNITLEVPENVKR"
     gene            29447..30739
                     /gene="brnQ"
                     /locus_tag="KOU88_003031"
     CDS             29447..30739
                     /gene="brnQ"
                     /locus_tag="KOU88_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBK3212887.1"
                     /translation="MGKTKDVIVFGFALFAMFFGAGNLIFPPYLGIITGPEWLIAFLG
                     FTFADAGLALLAVMATAKFDGNVVEMFKRCGMKLGILIGCADILCIGPFLAIPRTGAT
                     TYEMGIMPLFGTSIPVLLFCILFFAISYVLTIRPSKVVDIVGQFLTPALLIALAFIII
                     KGIISPLGDIVDKPMIPNVFAEGIGQGYQTMDAFAAIALASVLIVSLNDKGYSTISDK
                     LKMIGKAGVLACGGLALVYGGLCFLGATVSTMYGTDAVQSQVIVNITEGLLGNVGKAI
                     LAVVVSLACLTTSIGLTSATGQYFSRLTKGKLSYEKIVLAVSVFSAVVASFGVGTIIK
                     IASPILSIVYPPSIVLIILAFFNEKIKNDNVYKGAVYMSLLVSILTVISSYGVAVPVV
                     NSLPLNSLGFNWVVPVIIAGIIGNFIPSKSQSNTLGTN"
     gene            31858..33150
                     /gene="brnQ"
                     /locus_tag="KOU88_003032"
     CDS             31858..33150
                     /gene="brnQ"
                     /locus_tag="KOU88_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBK3212888.1"
                     /translation="MGEKQINFKDVIVIGFALFAMFFGAGNLIFPPYLGVLSGSSWLV
                     AFIGFLFADGGLALLAVIAATKFNGDTSKMFSRAGKGLSIALGCAMVICIGPLLAIPR
                     TAATTYEMGILPTIGSGISPVIFSIVFFALVLVLTIRPSKVVDIVGSILTPALLIALA
                     VLIVKGIVSPLGEIRDSSLIQNVFAEGITQGYQTMDALAASVFASIIIMSVIAKGYTG
                     EKEKMKATISAGVIAVIGMALVYGGLCYLGATVSQQYGQDVQQTALIVAITAALLGTT
                     GKILLAIIVALACLTTAIGLSSAAGQYFSTLTDGKLKYEHIVIVVCVFSAIISNFGVS
                     TIIQFSSPILSMVYPATITLVILALFSNKIKNDNVFKCAAYMALLVSVLTVATSFGVK
                     IPLVNSLPFASLGFNWIVPVVIAGIIGNFIPSKSSKTA"
BASE COUNT        13874 a         3312 c         5714 g        10507 t
ORIGIN      
        1 tttatgataa gagaaatagg atatttagat gatgaaaata atttaattgc catttctaaa
       61 tacaaagagt gttataaacc ttctatagaa caaggtgcag tggtagacat gaaggttaaa
      121 actgtgctta ttgtatctaa tgtaaataat atagaactta aaattgaccc aacaataatc
      181 tttgcaacac tcaaagatat acaagactta gaaactaaaa taggtactgt taatactaaa
      241 attgatacaa ctaaaacaga attaacaagc aacatagaaa ctactaaaac agagctaaac
      301 actagaattg acacagaaaa tgagaaacaa aatattaaaa ttgaccaatt aatcgcaggt
      361 ggttctaatg tggcatctac tcaaacaata acaattgacg attgggttga ggatgcagaa
      421 aatggattca aagcaactgt aacacatagt ttgttaacac agagaatagt tgtaaatatt
      481 atagatgcta ctacaaaaga aaatgtagtt acaaacttta aaattataga tgataattct
      541 atagaaatta gaagtgaaac aaggtcagaa ttaaacgttt atgtgataaa tggaaatgca
      601 gaaactcatt ttataaatgc gactgtggat gataacagag tgtctgaaat gactacttat
      661 tcgtctaaaa agatacatga agaaattagt aaggtagcag agcaattaac aggaattaat
      721 agcaatatta tatcaacagt aaataataat ttaataccaa tgtagaaagt gaagtgatac
      781 aatggctgat cattataatg tttatagaac cgttaaaaaa agaagaggtt attattcaga
      841 gcaagatgtt tttctttcac cttgtccata tgaatatgta agtggttatt atcgaaatac
      901 ttattatggt gtgtttgatt taagtagtta caaagatata gtagttccta caagtgctaa
      961 acgagaaaaa acttcaactc gtgtttattt tatatctggt ggaaatatga taaataatga
     1021 tgatagtatg aaacaagttg ttactattga acttatacca gaccctacaa ttaatttaac
     1081 tctaagtaat attagtaaag gttgtactat cgattacaat atcatagaca atgaacctac
     1141 tcaaagattt atagtaacag aaaaattaaa tgaaacagtt atagcaacaa aacccaattc
     1201 cattggtggc aactatagca ttttacttac agatgaacag atattgccac tacaagtaaa
     1261 ctcgcaaaat aatatcacta tagaaattag tacagaacaa ggtggattag ttgtaagtaa
     1321 gacagcaaca tttacaagaa taaataataa accaactgtt ttagttagtt catataattc
     1381 taattctgca aaatttacag catctgattt agataataat ttaagtaaaa ttgagtggta
     1441 tttagatgat gtattaaaag aaacaataac aacagattta acagcagaga aaacaataaa
     1501 ctatgaactt acagacaatg caatacacac attaaaaata gttgctacag atgcagaaaa
     1561 tgcaacagtt gagaaggttt taagtataag taaagagata atgccacttc aatctgatgc
     1621 tagtttaagt gatatatcaa ctaagttgat agagattgga gaagggttta agaatgggaa
     1681 aacaagtatt ataaatactt tatcacttaa aaatatagaa gcaaatctaa ataacacctt
     1741 agtggagtta tcagagaaaa ttaaaacgag ttttaatagt tcagacgcta gtgtacagga
     1801 attgcaaaat ataataacac aaaaaaataa tactataagt caattaaata cccaattagg
     1861 acaaagaaaa agatgggcaa aaggaacatt tgaccaaagc aaaattacag gtagaagtac
     1921 aactattcca atgaatttat cttttactcc gtcaattatt tttgttagtt gtggaattaa
     1981 ttttagtttc gcatatgctt cagcgaggtc atgcaatctt aaatttttta caaatctcat
     2041 gaaagcaaat cctacaactt caacaattga tgatgaaaat tttaatggtg ttgtgtttgc
     2101 aactgttaaa gaaattaata aaagtagttt tgttttatat cttaaaggat tttcatacaa
     2161 tggttcagac gcagaagtga gtccccttgc tggaacaaca tttaattgga cagctataga
     2221 ataaaaaacg aggtgataat atgaatagaa aaaatagaat aatttacgac caattaggaa
     2281 atatatggct tcaaactggc gaagcaatgg gagatataca agagtggtca gaaataactg
     2341 aattaaactt tttggatgtt gaatttggaa gtatagacta tagtaaacag tatatagagt
     2401 ctataaatcc agttacaaaa gagcctgtta taaaagatat agaggttgta ttaactgatg
     2461 aacaaaagag attagaagca ttagaaaaag aattaaatat attaaaagaa ggtaataaag
     2521 atagagatag tgagatagta aacacagcat tcgaagtaga aaatataaga ttaaataata
     2581 atatttagga ggaaatgata tgtataactt attaaaatta atgatagaac aaaagaacta
     2641 tagtactaaa gaggatttac aacataagat ggatgtattc tatgcagtaa ataggattac
     2701 agaagaacaa tatttagaac taacaaattt attaaagaaa gaagaaatac cagcagaacc
     2761 aacagtttaa gagaggttct ttttttatag acttagataa tttctaagtc ttattttaat
     2821 gcaaaataag gaggaaatat gaacgtaaca atagtttttt tagcaacaaa tatatttata
     2881 aaattagtaa tattagcaat agcatttgat acactgttag gttgcttaag agcaataaaa
     2941 acacatcagt ttaattcaag ttttggaata aatggaggaa taagaaaagt cgcaatgata
     3001 gcatgtatat tttttctagc agtagttgac attcttacaa agtttaactt tttatttatg
     3061 ttaccacaag attgggttga tttcttacga ctaaatcatc ttggaatatc tgaatttttc
     3121 tctattttat ttattctata tgaaagtgta agtatattaa aaaatatgta cttatgtgga
     3181 ttaccagttc ctaaacgatt aaaagagaaa ataggtagtt tattagatac tatgacagat
     3241 gaattaaata ttaaaggagg tagtaaataa tgaaaatatg tattacagta ggacacagca
     3301 ttttaaaaaa tggttcatgt acttctgcgg atggagtagt taacgagtat aagtacaata
     3361 aatctcttgc cccagtatta gcagatacat ttagaaaaga aggtcataag gcagatgtaa
     3421 taatatgccc agaaaagcag tttaaaacta agaatgaaga aaagtcttat aaaataccta
     3481 gagttaatag tggaggatat gatttactta tagagttaca tttaaatgca agtaacggtc
     3541 aaggtaaagg ttcagaagtt ctatattata gtaataaagg tctagaatat gcaactagaa
     3601 tatgtgataa actaggtaca gtatttaaaa atagaggtgc taaattagat aaaagtttat
     3661 atatcttaaa tagctcaaaa cctacagcag tattaattga aagtttcttt tgcgataaca
     3721 aagaagatta tgagaaagct aagaaactag gtcatgaagg tatcgctaag ttaattgtag
     3781 aaggtgtatt aaataaaaat ataaataatg agggagttaa acagatgtat aaacatacaa
     3841 tcgtttatga tggagaaatt gacaaaatcc ctgcaactgt agttggttgg ggttataatg
     3901 atgggaaaat attgatatgt gatataaaag attacgtacc aggtcagacg gaaaatcttt
     3961 atgtcatagg gggtggagca tgtgagaaga taggttctat aactaaagag agatacacca
     4021 tgataaaagg taatgatagg tttgacacac tttacaaagc attggatttt attaatagat
     4081 agattgagga ttgaataaaa tccatttaca cttttcttac atttcattta cacttttaat
     4141 acaaatatac tataaaaata cgatataatt aagacagtta aatttataat taatattagt
     4201 aagaatcttt aaaataaata tagcaacagg tatatcataa caaataaatg acgagaatta
     4261 gagatagtta atcatgagga taactgtctc ttttttattg tcgaataaat cagagagtga
     4321 agggattgaa tagaatgaga aaacttgata atattaagaa gggcactata attttagata
     4381 taattcctaa tagtgcaaat gggagagatg caatgaaaat tgaaaaaatt gaaattaaag
     4441 gtattggtgg aataaaagaa ttaagtctga ggtttaataa aggacttaat ataatatgtg
     4501 gtgcaaatgg tataggaaag acaactattt tagaagttat ttcacatctt ttttctatac
     4561 aatcttctga tttaaagaaa aatgcaaaat ttgatttagg agaagcaata gcggattatt
     4621 cgtttgaaga tatagaagct gtacataaaa gtacttatca aatcaatgat ttcaatgctt
     4681 ctgtgaaaga acttattttt gataatcgag ataaaaaaaa atatagtaaa tttgtgttgt
     4741 tttttaagac acatagagaa ttaaattatt caaaattgga tggaataact ggagatgaaa
     4801 catatagtga tgatagtaca tcttatatgg ctgatttagg tatagattca agtaaaataa
     4861 aaaattggtt tattaataga cttctttttt ctaagcaaga aggttctctt acaaaagaac
     4921 aattatgtaa tttagactta gcaatagaaa tgattagtat tttagataag aatgtatcat
     4981 attctagaat tgtatcagat tctttagatt taatgataaa tactcctcaa ggagaaattt
     5041 atatagaata tttatcatca ggatataaat catgttttta tatattatta ggtataatta
     5101 aggaattaga atatagattt actaaacctt atattgaagt taaggatttt gatggtgtca
     5161 tactaattga tgagttagac ttacatctac atccagaatg gcaagttaaa attgtaaatg
     5221 cattaaaagt attgcttcca aaggcacaaa ttatagcaac aacacatagc cctaatatga
     5281 tacaaacact atcaccagat gaaattatac cattaaccat ggatgaaaat ggtaatgtgc
     5341 gtaaaaaaga cttagagtta ggtgaatatg gattgcaagg atggactatt gaagaaatat
     5401 tgacagatgt catgggaatg aaaacaactt cttctgagtt atatttagat acaatgaaaa
     5461 aatttgatag agctatggat aaagagaatg tagatgaaat caagaaatac tatgatatct
     5521 tgatgaaaat gttacatcca aatagtacac ttagaacaat actgaaaata caagtggcag
     5581 gaataataga ttgataaaaa taaatagaac aagaaagcct attgaattaa cagaagaagt
     5641 tcagaaacaa ttaacagaag aatttaaaaa taataaagaa aaaagcgtgt ggaggaaaaa
     5701 gtatattaca aatgctctac ttgagatgtc tcatggaaaa tgttgttatt gtgaaatgaa
     5761 attgatagaa gagggcaaat cactgaatgt agagcatttt caccacaaag acaaatatcc
     5821 tgatgaagta gtgaaatggg aaaatttatt gccatcttgt gggagatgca atagtgaaaa
     5881 gggtactcat gacactaaat tagaacctat aataaatcct gcaataaata acccaaaaga
     5941 ttatttatat ttatataatt atagatataa aagtaaaaat agaaataaac ttggtagtga
     6001 tacaattgat atattatatt tgaatgatac agacaaatta attaaaccaa gagtaaatat
     6061 ttgcatggct ttattcaaaa ggttagagtc tataaaaaca tttgttgaag attatcaaaa
     6121 tggtacagga acacatacaa gaagaaaaaa taaaattata aacgaagtaa aaggtgtatt
     6181 aagatgcgct caaccaactg aagaatatag tgctattgtg gcaaatgtta tagtaaatga
     6241 tgatgattat aaatacataa aagaaataat gtcagaattt aacttgtggg ataatgaact
     6301 agaagaatta gaaagtaaag caaaagaaat aatgttagat tcagaatgaa atacatatta
     6361 aaataactag atacaattaa atttgaaagt ataaaaaaag aaggtgataa aaatttcttt
     6421 atcatcttct ttttttatac tttctttctt taagtttttt ctttttcata tcttctaata
     6481 catctaatgc agtagtataa aattgtattt catctctgta aggcacagct atatcaagag
     6541 atgtattaat agctataaat atgagcacta ttatagatga ggattgcaga attaaattta
     6601 tataattatc tttaatattt aatgaactta aaaataaatt agcaagtaat gaaaaaacaa
     6661 cagccataag ggagaaaaac aatgcattac caggattatt atttttctct aactgacctt
     6721 taattctagt ttgctcaatt tctatctttc taattgtatt aatattctta atttcattgt
     6781 aatgattata aatttttgtg taatattctt gataatttat tacactttct ttatttccct
     6841 taaagtattt tatatccttc ttgatttgtt ttttcttttt tatattttta aaccaatatt
     6901 tcaaactcat aacccctcca taaatccata taatatactt taatttataa cacacttaat
     6961 aatatatatc agcaatttgt cgaacgattt taaataaaaa tagagccagg atacaagaga
     7021 aaaatttaca gagatttatt ctgatgatgt gtggtcaaca atggataagg ctagataatt
     7081 tgtaaagaca aaattataag ttttatattt ataaagataa agctttgata tatttcatcc
     7141 ataattttca aagacttata taaaaaggag tgttttattt ttctaaacac tcctttttat
     7201 ataagtcttt caataatcaa tttttaaaat taataatatt gctattattt ctttttcaag
     7261 tttatagttt cttcattttt attccaagat ataattactt tataattaga ttccctattt
     7321 gaataaagac ctggtctttg tctttttatt attttttctt gacctgattc taaaactgca
     7381 tcttttaaaa ttataattgc atcttcacca tctataaact catatgaata attaaatttt
     7441 tgcttaacta catctttact gtctttatat tttatttcta attctgattg ttcttcagta
     7501 gtaacaaatt tagctgtcca atgttctgat tctccaataa agatattttt atcatttttt
     7561 atattaagta caactatcgc agcgattact aaaactataa aaatacctag aaaaagtttt
     7621 tttctcatac tgagccctcc tttgaataat tatatgtatt ataacatgaa aacagttatc
     7681 taacatcatt attatgaatt ttctgaattt ttttgatatt tatattctat catgatagaa
     7741 tatgtggtat aattaataaa aaaggaggga ttagtatgaa ttctaggttt aaaaaatctg
     7801 caacaagtat tttatcttta cttgcaatga caatactatt accagcaagt gtaaatgcta
     7861 gtgaagtaga aaattcatct atgaaagtaa catattcaga gaaacaagta acagatatga
     7921 acaagttata tgatatggct aaaaatggaa tcactgatgt taaaagtccc aacgaaaaag
     7981 gtataatcaa aaatgaaaga acaggagaat ctatgtatgt tgatgctata tcaacaacac
     8041 aattattaga agtcaaacaa tctaaagatt taacatctaa gacatattct aaaacagttt
     8101 ttttagatac tgatacaata aagcccctta gaaaagcaag tatatcagaa gacggatggg
     8161 ataaaactgg tggtgtaaaa gcatctggta cagttacata tacaatatca aaaggagatg
     8221 gagcattcca atatatttct gtcagtaaag tttctggaaa ctggtctatt gcagatggtc
     8281 agattcgtgt aacaaataga aaggtgtaca taaaccaaac tggatttgtt tctaatggat
     8341 taggaattaa gcaacaacaa aggaaagacc caacatcaaa ttctttttca tataatgcac
     8401 cttctagttg gaaaccagtg ggtagagatt ctcttcaata caattgtggg tttgaatcaa
     8461 ttgcaacatt agtaagagga ggaagctctt ggtcattcaa tttcatcgtt caaccttaaa
     8521 acattttaag tgaattttat taaaattaaa gatatattga caccataaag atataataaa
     8581 aaataaaatt atagtaaaaa ttgtaataat aaagcgaacg aaaattatca tactaaaaca
     8641 taagacatgt tataattgta ttatatatac attaacatac accaaagcac tcttataaaa
     8701 agagtgcttt tagtgtatat ttttttactt ttttgaatga tttttgtcgt atgaatatat
     8761 tctgaataag gctttatgat aaaataaatt taaaggagtc tttttatatt aaaaattaat
     8821 attttaaata tttagaattt ataaaacttt agggagataa aactgatgtt gttaggagat
     8881 gaaattaagt tgaatttaga gccaagtgat ttaataaatt ctataccata ctttaaatct
     8941 gaatattcag atttatgtgg tttagacgca gattttataa aggaacagtt attgaaagct
     9001 gaaaataatg atagaatagt gagtatggct cgaggagaag gaagagcatt tgttgtggaa
     9061 ccaattatta agcgtaataa ttattgcaaa tttagaaata attcatatga tatttttaat
     9121 tcaattccat cttatgaata tgcaataaaa ataatagaac gctataaaaa ccatattttc
     9181 aatccaactg aatatcgcaa cagtgtaatg agaagagtag gaacatatga aaatgatatt
     9241 ttcaattggg gatacaaatc aatgcactct tatatggaat cattaccttt aagagaattt
     9301 ttagagccaa ataaagttga tagaacatta ttatttgagt ttcttgattt tatgagagaa
     9361 cttttttcat atcagttaag aacgtatcca ggacgttttg ataattccaa aactttagat
     9421 gccatagaga ccataaaaaa tgctatcata aaaacagaat cacatgatga tttgcttata
     9481 attaaagaat ggttatgttt tttattgcat actggaaatc atagagtatt taaaaatata
     9541 actccatgga tttcattgtc tacaggaagc aaaagatata atattgtaca taaatttgct
     9601 tctcgcaaac catttacttc ttatagaaca atatctgaga aacatactta taacgaaaaa
     9661 gaaaagttta tatttattga ttattgggag tatgtagata aggaaaattt aacttttagg
     9721 aatacaaatt acattgtcaa taaacttaaa agtatgggag taaattggta tgaaaataga
     9781 aataatgaag ttatggtaaa atatgcatta tttcctcaac aaattatagg gtattattat
     9841 tttgagaata gaaaattaca atattacttt attaatcctc attatttgaa agcatggcaa
     9901 aaaaataaag attttaaaat aggagatgaa ctgtacataa atcaagaaca agtagtgttt
     9961 ccttttaata atccgtatag agtaatatac ggaaaaaaat atggacatat ttcagtagtt
    10021 gataagagat aaatattttt aggctctaat tataaataaa acaatattat ttatcttttt
    10081 ttaaaattaa tgacataaaa atatatctta tatattgtta tcaattatta aataaatctt
    10141 atattgcata tggaataaat tggaaaatat acttatccta atttaattga ttacatacta
    10201 ttattagtat aaaatttagt tatacataaa ttggtaagag gtgtaaacta atgaagatta
    10261 ataaattacc acatgcagaa ctaaaactaa tgaagtatat ttggggagta gatgatgtat
    10321 tagcctcaag agatatcata gaagtcatga agttgaagta tgattggaaa aagagcacaa
    10381 cattgacatt tttaaaaaat ttagtagata agggcttttt aactactgat aaggtagata
    10441 gatgtacgca ttatactata gctataaaag agaaagatta cttaaaagtt gagacaaaga
    10501 gtttttttag ttttatgcat aacaattcat ttaagagttt tatttcagca ctacatgatg
    10561 atgaagtttt agatagtaag agcttggaca aattagaaga atactttaaa aatttgaaag
    10621 aagaagatat tgatgactaa taaagctatc agtatctttt tagtttgaga caattgagag
    10681 tagcgtttgg atttaatgtt agttttatgt gatggtagaa cattatataa agaaaagtga
    10741 ttatttcctt agtgtttgat agtaaaaaat atagagaata ataccaatta aaatttaaag
    10801 atatatgaaa tactacaata gcttaaatca tgtaaatatg ataaagatat tgaaattata
    10861 aaaggaatat aattttagaa gaaatagttg acagataaat taccttacta tattattgta
    10921 ttaataaaat aatacaataa tatagtaagg aggtaataaa tgaaatctag aaaacataat
    10981 attacaaaag gattatttat agtttacata attattttaa catggataat actattcaag
    11041 ttgcaatttg atatctcatc ccttgaaacc atgaatctta gaagcataaa cttagtacct
    11101 tttgctgggt cacttataat taataataga gtagatatat cagagattat attaaatgtg
    11161 gttatatttg taccatttgg gatatatgtg tgtatgctaa aagaagaatg gagctttata
    11221 aaaaaagtta tacctatttt tataactagt ttggcatttg aaacacttca atatatattt
    11281 gcactaggtg caagtgatat aacggatttg ataggaaaca cactaggagg aatcatagga
    11341 atagctgttt ttatgctatt atcgaaaata tttaagaata ataccataaa aattatcaat
    11401 gtattggcat tgattgtgac aattattgtt gtattatttt taggattagt tatttttgca
    11461 aacttataga aataagtata tatgtttagc ttaaaataga acgtaagata cagttacata
    11521 taaaattatt tacacataaa aagcacctat acaggtgctt tcctaaatta ttaaagaatt
    11581 attgtatctt gaaactcttg tatgttcaat tcttgatttt ctcttgtttt ttctaataaa
    11641 tctaacgcac aatttataca aactttaatt tctgcattgg tatttttctc ataataagtt
    11701 atatatttat ttctatattt atctatttct tttccacaac gactacacat tacaattacg
    11761 ctcatatctt agttcctcca tctctaatta ttcttaatat attcaatagt atcacttttc
    11821 tgaaaataat gattgttaaa actgtatcaa atttagattt actttttatt ataatgcatt
    11881 ttaataaaaa aataaaggtt atgggtaaaa tatttataga aaaaagtata ttcttgaata
    11941 gattataaaa ttttattatt ttttagcagt attaaataca cattaatatc tataaaatga
    12001 caaaataaaa aatactattt aaatagatat taaaaaattg ataccaagta tttgtttgct
    12061 atatgaataa caatttattt aggagcttta cttggacact gtataataat aaagtaattg
    12121 ctaaaaacgt ttgatgattt ggatgtattt ttagaaatta gaaaaatata tacttactga
    12181 ctaatgataa tcttatatgt attttagttt gagtgattta agaaaagtgt tttgaaaggg
    12241 aattatttta tagagtaaat aaatatataa tagtagaaaa ttacatataa agagtagtgt
    12301 ttatttcatt accttcttta tctgttccga tagggtcttg tagagatact tgagttttat
    12361 tttttttgtt agatctaata ttcattaaaa tctcattttc aatacatcta gaagcatatg
    12421 ttgctaatcg agttccttta tctatgttat aagtttctat agctttaatt aatcctattg
    12481 tacctatgga tattaaatca tcctgatctt ccgttgaatt attatatttc tttgctatat
    12541 aagctactaa tctcatgttt ctttcaatta atgtatcttt tgcactttta tcgttttcta
    12601 ttttaaattt agttaaatac tcaatctctt cttcaggggt taagggtttt tcaaaagatt
    12661 taagagctgc caataggtca cccccttttc aacggtcact ttaaattata tgaaggagac
    12721 ttatccaagt tgactgttat ctaataaaat aatatgcata tttttagaat ttaaaacata
    12781 tatttgcaaa cttttgaatg gaatatgaca taaagagtgg gaatttaaat ttaagttttt
    12841 gttgtatata tatgaaataa ggcgaagaaa ttattgattt ataaagtata aattggaatt
    12901 gaggtgtcaa taaatataaa aggaaatagt atttatatat gttttggtgt tgaagtaaaa
    12961 gattaatgca aagcattaga gtctataaaa atatgaatat aggaggtgta attttacaat
    13021 acttaaaaaa gtaaatgtaa ttaattgttt gtataaagtt gattacaagc aaaagtatca
    13081 gtcatagtta atactgttaa gggtgaaggt ggtgtgttaa tttatatatg tatgggaaga
    13141 aattttgatt acaatgaaaa aacttacaaa agatatttat gaaaaaactt atagttaaat
    13201 gtttatatat aaaatattat ttaggggttg tttttattat tgaaaataag aaagagtggt
    13261 tttatatcaa ttgaatgtat aataagtatt gctatattat atgtggctgt ttatttagtt
    13321 tctacatcat tgtataattg ttatagtttt atcagtagaa atatatctga cagagaaatg
    13381 ttaagtacag caaaaaaata tatagaagat gagaagtata gaatacaaaa tagtaagtat
    13441 gagttaattg aagataagat agaaaaaaat tacataaatg gatatgaaat taacagtaaa
    13501 atagagcaaa ttttagatta ttatcaatgc tatgaaataa atatagagat aaaaaatgaa
    13561 tttaaaaaac tgaggtttaa tagctatgtt actagaaaat aaaggctcta tattaataat
    13621 aacattgata atattttcta ttataagtac tgtgtgcatt atgtgtatag gtttaattta
    13681 tacacataat aatatgtttg agttaggata caaggacatt caactaaaag aaatttcttt
    13741 aagtggaata gaaatatcag taagtaatgt actttcttgt gttgaggaag ctattgatgt
    13801 atctaataat gaagacgaat ttagagaata tttcttagga aataatatga ttgaatgtat
    13861 aaaaaaaata aaagatacat cttatagtag tttagaagaa ctttctttaa aagtagaaaa
    13921 taatactatt tatgacagag gagatttttt tgaatttgat atagaaagta atgttagaga
    13981 aaaagaattt ttaaaagcaa taaaagtaag agtgaaaatc aaaaatccat ggataggaat
    14041 tgacattgaa gattatatgg ataaatctaa taacaataaa attgatgaca aaacattcaa
    14101 taattataaa gcatctgaaa ataatgaaat tctaaatcaa tttaaaaatg aaagtgaaaa
    14161 tataaggaat caagaggttg gtggatttac agaagaagat gaagaatatg aagaagaact
    14221 taaacaaaac ataattgaaa atataaagaa gaattttgat gaaaaaaacc tagtacaggt
    14281 atataagtat aggggtgtat aactttgaaa aaagaaggaa tgtgactgta atagaattaa
    14341 tagtatctat cagtataata ctcttgatag ttacattatc ttttccaaaa gataatcttg
    14401 aaaatcataa aataaattta tttgcacgtc aactttgttc agatataagg tatgttaggc
    14461 gaattaatat gtttagcaac tacaatacat atatatatta tataaatcaa ggtaaacacg
    14521 aaggttatgt attgagaaaa gatggtaaaa acattaaatc aataatgcta cctaaaaatg
    14581 caaaaatagc taggagtatt gaaataataa agtttaaatc tgatgggtcg cctcaaaagg
    14641 cgtctacaat agagatatat aataatagat taagaaaaac tataacaata acacctgtaa
    14701 gtggaagagt acttctgaaa gagggaaaat atgaaacata aatatggtta cttgcttttg
    14761 gaaagtgtcg tatcattgtc ttcaatggtg ataattatac tagttttata ttctatattt
    14821 ttgtctacaa taaacttaaa gttaaaagta gaagataaga tagaactaca acaacaaagt
    14881 cttgaaatca taaaatctat ggaaggaatt attagcaatt ctatgggaat aatgaatgta
    14941 tctaattatg aagaaacatt taaaaagaca acatctataa aatgtagata tttagatgaa
    15001 aataataatg aagaaggcat aagtaataaa gaaattatat tgaatgaaag acgaaataag
    15061 ttatttgtaa attctttaaa tggcgaaagt agtcaagcag gtggttatga aattggagat
    15121 tatgtagatg agatgtatgt atcaattact aataatggtc aatatgttaa tattaaattg
    15181 aaattatcaa aacgtagtca aaaatatgag actgatttca aaataaaagt atggaatttt
    15241 agtgaaagta tataaaaata cataaattta agagaaagaa gtgacatcaa taagtcatat
    15301 aaaatataat tattgagaac tatataacta aataatatca atatgtaaag tgtatagatt
    15361 aagaatatag aggataataa taaaaatata gaataagtaa tttgccaaat acttgtttat
    15421 attgtataac ttatgatatt atgatattag taaaaatttg taatcctgac ttgacagaat
    15481 tcaagtaaga gatataattt taaaggcata gtaatgtaaa atttactaaa aaataagaaa
    15541 tttattttaa tatggaggaa caaaaaatgg tatcagcagg tgattttaga aaaggtgtta
    15601 catttgaaaa agatggacaa ccatgtttag tagttgattt tcaacacgtt aagccaggta
    15661 aaggagctgc tttcgttaga actaaataca aaaacttaaa aacaggagct ataagagaag
    15721 aaagtttcaa tccaagtgaa aaattcccta aagctgttat agatacaaga caaatgcaat
    15781 atctatacaa tgatggtgag ttatattatt ttatggatca agaaaatttt gaacaaatac
    15841 cattaaacta tgagcaagtt gaagatgcaa ttaagttctt aaaagaaaat gaagttgcta
    15901 caataagatt ttaccaagga caaccattcc aagtggaagc gccaaacttt gcagagctag
    15961 aagttacaga tacagagcca ggtataaaag gtgatacagc aagtaatgta actaaagcag
    16021 ctacagttga aactggagca gttgttcaag ttccattatt tataaatact ggagataaag
    16081 taaagataga tactagaaca ggtgaatatt tatcaagagt ataaaaattt atgtatataa
    16141 aagcttatat gtcttaataa tataagatat atgagctttt agtttatata taaaaaagaa
    16201 agcgaggggt gttacatgaa acatttatat gaagaagttg catacttaaa aggcctagca
    16261 gaaggactag aaataagtgc tgaaagtaaa gaagggaaaa tgatacataa aatagttgat
    16321 gcattagaag tatttgcaga tgctattgta acattggatg aagaacaaga agaacttcaa
    16381 gattttgttg aatctataga tgaagattta gcagatttag aagaagatat tgctgacatg
    16441 gaagaagatc tttatgaaga agatgacgat gaggatgatg aggacttcag ctatatagaa
    16501 atggaatgcc caaattgtgg agagttagta gaaatagacg aagatttgtt atatgatgat
    16561 gaagtagatg ttgtttgtcc tgattgtaag gctgtgatat tatcatcaga agatgattgt
    16621 gatgatgatt gtacatgtgg tggttgttca agttgtgatg atagagagta aaaattcata
    16681 agaattaaaa ctgcctatga tgcctatgag atattttgct tcataggtag ttttattttt
    16741 atgaggaagg gtattatgta ttttggtttt gcaatacttg gacaaaaata gtacactaga
    16801 atttatagaa taggattttg gagggatgta aatatgaaaa taagtaaaaa attactagat
    16861 aatatacaaa gatttgaaaa tgttataaat tataaattta aaaataaaga atatatacta
    16921 gaagctctta ctcatagttc atattctaat gaaaataaaa aatataattt taacgaaaga
    16981 ttggaatttt taggggattc ggttttaggc atagtgataa gtgattattt atttaatgaa
    17041 gaagctaatc tgcccgaagg ggaactaact aaacttagag caaatatagt ttgtgaagat
    17101 tcattaagtg aagtagctaa tgatataaat ttgggtattc acatgttatt aggtagagga
    17161 gaagaagcaa caggaggaag acataggact tcaatattag cagacgcatt tgaagctgta
    17221 atagctgcta tatatcttga tggaggtttt gaaagtgcaa gacagtttat acttcatcat
    17281 atggaaaata taatttatga ttcaagaaaa ggaaatatat ttagagacta caaaacgcat
    17341 cttcaagagg tgttacaagg gaatggagaa aataatatct ggtacaggct tatagaagaa
    17401 aaaggaccag accataataa aagatttgta atggaagttg gaattaatga cgatgtactt
    17461 ggtataggag aaggcaagag taaaaaagaa gctgaacagt tagctgctaa aatagcttta
    17521 aagaaaaaat tatgggaaaa ataaatataa tatgtaaaaa tataaaaaga aatatttata
    17581 ttagaaggat gttgtagatg aaaaagagaa ttatacctat atttgttcct cacaaaggat
    17641 gtcctcatga ttgcatattt tgtaatcaaa aaaaaataac aggtgtgagt actgatgtta
    17701 ctagtgaaga tgcaagaaat ataattgagg aatgtttaga gactatagat aaagatgcag
    17761 atgtagaaat agcatttttt ggtggtagct ttactgctat agatattgat atacaaaaaa
    17821 gtttattatc agttgctaaa gaatatgtag aaaaaggtct tgtaaaagat attagaatgt
    17881 ctacaagacc agattgtatt gatgaagata tattaagtat gttaaaagaa tataagacaa
    17941 gtataattga actaggagta caatccttag atgaaaaagt attattagat agtataagag
    18001 gtcatcaatc tgaaattgta tacaagagtt caaagatgat aaaaaatagt ggaatcaaac
    18061 ttggattaca gatgatgatt ggtcttccag ctgacacaga agaaaagtgt atatttacag
    18121 caaaaaaatt tgtagagcta aaaccagatt gtgttagagt ctatccaact ttggtagtaa
    18181 aagatacagg tcttgaaaag ttaatggaac aaaataaata taatccattt actcttgaag
    18241 agagtgtaaa tatagtaaaa aaagttcttg tactgtttta tgttaataat atcaatgtaa
    18301 taagagttgg gcttcaagct actgatgata tacaaattgg aaaagctgtt ttagcaggac
    18361 catatcatcc tgcatttaga gagttggtag aagcagatat gataaaagat tatttagaat
    18421 ttgttatttt gcaaaataaa aatataaagc aaatgttggt caaatctaat aaaaagaata
    18481 tttctaaaat cataggaaat aaaaaaacaa atgttaaata tatggaagaa aaatttggtg
    18541 tgcttttaaa aacacaagaa tcagatttag atataaatca attagaaatt gtgttagatg
    18601 ggaaaagttt aattagtgct aatatgagag acattcatag aaaattgtat gacatttatg
    18661 acctttagtt ttaataatga agggagagaa aagatttgta tttaaaaaga ctagagttaa
    18721 agggatttaa atcctttcca gtaaaaacag atattatttt taaagaagga ataacagcca
    18781 tagtaggacc aaatgggagt ggaaaaagta atatatctga tgctgtaaga tgggtattag
    18841 gagaacagag tattaagagt cttagaggtg ataaactcga agatgtaata tttgcaggta
    18901 cagatacaaa aaaacctatg aattattgtg aagtggctct tactattgat aattctgaaa
    18961 atcaattgga attagatttt acagaagtaa ctataagaag aagggcttat agaaatggtg
    19021 aaagtgaatt ttttctaaat aataaaagtt gtagattaaa agatataaaa gaagtctttt
    19081 tagatactgg tattggaaaa gatggttatt caatcataga acaaggaaaa gtagatgaaa
    19141 tattaagtaa taatccttta agcagaagaa aagtttttga tgaagcttgt ggcatatcaa
    19201 aatatagata taaaaaacag gaagcagaaa ggaatttaag taatacaaag gaaaatttag
    19261 aaagaataga tgatgtatat atagaaattg aaaatcaatt aaagcctctt tttaatcaac
    19321 agacaaaggc aaaaaagtac ttggaaataa gtgaaaaatt aaagacactt gaagtaaata
    19381 gctttataag agaaattgaa ggaatagaaa aagaattaag tgaggttaat gaacatcgta
    19441 aggttattga aaaggagctc aatgaaaaag aagaacaaaa aaatgttgta gagaaaaagc
    19501 aagaagatat taataaagag gtagaggtat tacaagatgt aattgaaaaa tctgtagatt
    19561 atataaattc aattaaagga gttatatcaa aaaaagaatc ccaaataaat ttaattaagg
    19621 aaagaataag aaattttacg aatgaaatta gtagaaaaaa tttagaaata aatgatataa
    19681 aagagaagct aaatgaaaat aagcaataca taaaagaatt agaaagtaat aaattatcag
    19741 gtagtgaaga actatctacc ttgcaggaaa atataaaagt attggaagga agtaaagata
    19801 aacaaaaaat taagttagaa tccctaaata atgagataga attattgaaa gaaagtataa
    19861 ttgatatatt aaataagaaa caagagttta gtaataagct gtctacttta aacgcaaata
    19921 aagaaaatat gaatatcaga gatgaaaata taaattcaga gataacagag ttaaacaaaa
    19981 atattgaaat aaaatcatct gaattagata ctataaataa agaatttaat atgcaaaatg
    20041 aaaatttaaa gaatgtaaat aatagacata aagaattatc aattaatttg caggattcaa
    20101 ttagtgaaca caataaacta gaagatgaaa tacagaaaag taaatataat ttaaatggat
    20161 ataattcaaa gttaaatgtc tatatagata tggaaaatca ttatgaagga tttaatagag
    20221 gagtaaaaga agtactaaaa aataaaaatt taaaaggagt tcatggagca ttaggacaga
    20281 ttataaatgt acctgaaaag tatgagaaat ctatagaagc agctcttggt gcttatatgc
    20341 aaaatataat aactgataat gagtttagtg ctaagtctgc aataaactat ctaaaacaga
    20401 ataatttagg tagagtaaca tttcttccat taaatataat taaatcaaat aaaataagtc
    20461 taggaaattt aaaagcaaat actaagttca taggaatagc aagtgattta attacatttg
    20521 atgaaaagta tagaaatata attgaaaata tacttggaag aacaatactt ataaataata
    20581 tagatgaggg cataaaattt gcaaaagaaa ctggtcatag gtttaaaata gtaactttag
    20641 atggtgaaat cttaaatcca ggaggttctt tgactggggg aagtctaaaa actaatggga
    20701 atatactatc gagaaaaaga tacattaatg aatatacaga aaagataagt aatatcaaga
    20761 atgaaatttc acatctagaa ttaaaaagag aatctttaga caaagatgtg aaaaatataa
    20821 aaaatgaaat tgattcacat gaaagtaaaa taaaagattt agaaaaaagt ataataataa
    20881 aaagtacaag tataaagaat gttgaatctg aaattgaatc gttaaaaggt agtattacta
    20941 aattagaaaa tgagaagaat gatttaaatt ctaacctaaa ttatacactt gaaaaaagtg
    21001 atgatgttag aaaagatatg gaagagttag atgatttata caataaaaat aaagaaaaaa
    21061 ttgatgcatt gaatgaggaa ataaaaagat acaatgattt atatgataaa gaaaaatctg
    21121 aatttgatga attgaactta agtttagtga agaaaacaga agtttacaat agtatagtta
    21181 gagatataaa aagaatatct ggtgaaaatt gtgagttaga agaaaaaaat aaacaattag
    21241 aagagtcatt aaattatgaa gaacatgaaa taattaaatt acaagattct atactcactg
    21301 aagaaaaaga aaaagaaaat ttaacaaaac aactagggga tagtaataga aatcttgaaa
    21361 ctagaaaaat agcaaaagat gatttaaaaa atagttttga tgaaattaat aaagaattaa
    21421 aaactataga tagacagcat atagaactta aagaaagttt atttaaagtt ggtggaagat
    21481 tagaaagatt aaaaactagt caagacacat atataaataa gttgtttgag caatatgata
    21541 tgaccttagt acaagcattg gaaattaaag atgaagattt ggatatagat agaaaattct
    21601 tagaaagtct aaagagagaa ataagaagtc ttggaaatat aaatatagac tctataaagg
    21661 aatatgagga aataaaagaa agatacgatt tttatagcga acaaaagcaa gatttagaag
    21721 agtctatgga agagatagaa aaacttatac atactttaga agaaaatatg aaatctgaat
    21781 ttgaaattaa gtttgaagaa ataagtaaaa attttaaata tgtatataag agattatttg
    21841 gtggaggttg tggagaatta actattttag ataaagaaaa tttattagaa agtgatatac
    21901 taataacagc tcaaccccca ggtaaaaaaa tgaaaaattt aaacctatta tctggtggag
    21961 agaaagcttt aacggcaata agtatattat ttgctatatt gattacaaag ccaacaccat
    22021 tttgtatatt agatgagatt gaagcgccac ttgatgacgc aaatatattt agatttggag
    22081 aatttttgaa ggatttatct aaagagactc aatttatatc agtaactcat aggagaggaa
    22141 ctatggaagc tgctgattat atctacggag ttacaatgca agaaaaagcc atttcaaaag
    22201 ttattagttt aaaattaaaa gaagctcagg aaataacaga tattatataa cttagattga
    22261 cataggagga ataatagtgt taaaaaaatt atttggtttt ggaaaagaca aggaaaagga
    22321 aatagaaaaa aaagatgctg aagaagaaat agaagttgaa gacagtgttg ataatttaga
    22381 aaacttggaa gaaactattt tttcaggact tgaagaagaa gtgatagata aagtggaaga
    22441 tgttgaagaa aaaaatgagg aaagtgtcaa taatgaaggc actgaagaaa tcgaaaactt
    22501 tgaaaaaata gaagttgaga tgaatagtaa tggaaaagaa gtagaaaata tttcaaataa
    22561 tgattctcaa gaagagataa tcgaagaatt agaaaattat gatgaaattg agtctaaaga
    22621 gatagaagat aaagaagata agaaagttaa cttgtttgaa agactaaaac aaggattgac
    22681 aaaagcaaag caaggaataa ctgatagaat agatgaagtt ttaaaatcat atacaaagat
    22741 agatgaagaa ttacttgaag atttagagga aattttaata acagcagatg ttggtgtaaa
    22801 tacaactatg gatataattg aaagactaag agataaaata aagcaaaaag gtattactga
    22861 accaataaag gtaagagaag aacttaaatc tatagttgaa gatattctta caaatgaaaa
    22921 ctctacacta gatatagaac cagcaccatg tataatatta atggtgggtg taaatggggt
    22981 cggtaagact actacaatag gtaaactagc aaatagatac aaaaaagatg gtaaaaaagt
    23041 tttattagca gcagcagata catttagagc agcagcgaca gagcaattag aaatttgggc
    23101 aaatagaacc aatgtagaca taataaaaca tcaagaggga gcagaccctg gagctgtagt
    23161 atttgatgct ataaaagctg caaaagctag aaaaacagat gtattaatat gtgatacagc
    23221 aggaagatta cacaataagg ctaatcttat gaatgaactt ggaaaagtat ttaaaatagt
    23281 agatagagaa tttccagaag caaaacgtga agtacttctt gtggtggatg ctacaacagg
    23341 tcaaaatgca gttgttcaag caaagacatt taaagaagtt gcagatataa caggtatagt
    23401 acttacaaaa cttgatggaa ctgcaaaagg tggagtagtc cttgcggtaa aatcagaagt
    23461 agatgtacct gtaaaactta ttggagttgg agaaagtgta gaagacctac aagatttcaa
    23521 tgcaaaatca ttttcagatg cattatttgg taactaatgt tcttttaaaa ataatggttg
    23581 acaagagtgt tgttatgata taaaatacaa tagtgtaaag taaataacct ttacagtata
    23641 ctgctaggaa gtgtaagata tgaatataga aaaaatggtc gaaattggat tgttatttga
    23701 acagtataaa gaattattaa ctgacaagca gaaagaaata gttgctctat actatgaaga
    23761 agattattct ttaggtgaaa ttagtgaaaa tctgaatgta tcaagacaag gtgtttatga
    23821 taccttaaag cgttcagaaa aaatactaag agattatgaa gaaaagttac acttagtatc
    23881 aaagattcaa gagcaggaaa aaaatattaa gattataaaa gataaaatta ttgacattaa
    23941 agaagattta ttgcacaata gagattgtgc taatttaatc cctaagctag aaaatataga
    24001 agatgtatgt agggagatga taaaatgata tttgaaggat tgtctgataa actacaaggg
    24061 gcatttagta agttaaaatc taaaggaaaa cttacagaag tagatgtaaa aaatgctatg
    24121 agagaagtta aacttgctct tcttgaggca gatgttaact ttaaagtagt taaagatttc
    24181 ataaaaaaag ttcaagagag atgtgttggg caagaagtta tgcaaagctt aactccagct
    24241 cagcatgtaa tcaaaattgt aaatgaagag cttacaagtt taatgggaga tgtacaaagt
    24301 aaagtaatga tttcctcaaa gcctcctaca attttaatga tggttggatt gcaaggtgca
    24361 ggtaagacta ctacagcagg aaaacttgga ggatatttta aaaagcaagg taaaaaacct
    24421 ctattagtag cttgtgatat ttatagacca gcagctataa agcaacttca agttgttgga
    24481 gaaaaattgg atatacctgt attcaatatg ggagataaag aaaatccagt aaatattgcg
    24541 aaagcaggtt taagccatgc gattaaaaat gctaatgatt tagttattat agatacagct
    24601 ggtagacttc atatagatga agtacttatg gatgagttaa agtctattaa atcagaagtt
    24661 aagccacatg agatactttt ggttgtagat tctatgacag gtcaagatgc tgtaaatgtt
    24721 gcagaaagct tcaatgaggc acttggtgtt gatggagtag tattaactaa attggatgga
    24781 gatactagag gtggtgctgc actttcaata agagcagtta cacaaaagcc tataaaattt
    24841 atggggatgg gagaaaagct agatgatata gaacctttcc acccagatag aatggcatca
    24901 agaatattag gtatgggaga tgtcttaagt ttaatagaaa aagcacaaga aaatatagac
    24961 ttagagaaag ctaaagaatt agagcaaaaa attaaaaaac aagagcttga ttttgaagat
    25021 ttcttacaac aaatggaaca aatacaaaat atgggacctc ttgacaagat acttggtatg
    25081 atacctggta tgggaaatgt aaaagaccaa cttggagatg tagatttgaa tggcaaagaa
    25141 atgaagagaa caaaagccat aattcagtca atgactacat atgagagaag aaacccagga
    25201 gtattaaatg cttcaagaaa gaaaagaata gctaaaggca gtggaactag tgtacaagat
    25261 gtaaatagac tcataaaaca acttaatgaa atgaaaaaaa tgatgaagat gtttgctggt
    25321 tcacagaaga gtatgaagaa aaggggcggc ttaggcggtt tacctttttt taaataaaat
    25381 ataaaaaagt aaaaattatt cggaggtgac tgtaatggca gttaaaataa gattaaaaag
    25441 aatgggagct aacaaaaaac ctttctacag aatagtagta gctgattcaa gagctccaag
    25501 agatggaaaa tttatagaag aaataggata ctataatcca atttctgaac ctaaacaagt
    25561 aagaataaat gatgaaaaag ctataaaatg gttagctact ggtgctcagc caacagaagt
    25621 agttaaaaaa ttacttgtaa aaaacggagt aatagaaaaa ttcgaagctt ctaaacaagc
    25681 aaaataattt tttcttggca attagtttaa gtaagggctc attgctaagg ttactttagg
    25741 agatgaaata tatgaaagag ctagttgtag atatagctaa ggctctagtt gataatcctg
    25801 actcagttgt tgttgaggaa tttgaagata atgatggtat cgtcttaaag cttacagttg
    25861 ctcaagagga tatgggtaag gttattggga agcagggaag aatagctaaa gctataagaa
    25921 ctgtcgtaag atctgttgca aatagagaaa atataaaagt ttctcttgag atagtataaa
    25981 ataggaggat taggtataat gcctagtcct ttttatataa atgcgtagtt taagatttta
    26041 tgatgatatg accacataag attaaatttt ttaagaaggt gataacatga aagaaaaatt
    26101 aactcatttt aaggtaggtc aaatagtaaa tacacaaggt ttaaaaggtg aagtaagagt
    26161 ttatccactt actgatgata tagagaggtt tgatgaatta aaagatttct atctgggaaa
    26221 agatttaaat aataaattgg ctgttgaaaa agtaagatac aaaggttcta tggttataat
    26281 gaagataaaa ggcatagaca gcatagagaa agcagaaaaa ctaaaaaata aatttatgta
    26341 tgtatctaga gaagatagca gagagcttga agaaggcgaa ttttttatag cagatatgat
    26401 tggaatggaa gttttaactg tagatggaaa atatgtagga atactagaag atgttcttca
    26461 atactcagca aatgatgtct atgtagtaaa aggtgaggaa gataaagaat ttatgatacc
    26521 agctataaaa aaatttgtac ctacaataga tattgatgaa agaaaaatga ttatagaccc
    26581 tattaaggga atgatagatt aggtggtaat atgagatttc atataatgac actttttcca
    26641 gaaatattta attcgtacat ggatgaaagt ataatgaaga gagcagttga aaaaggtata
    26701 attgaggttc atatatataa tataagggat ttttctaata ataaacataa aaaagtagat
    26761 gattatccat ttggaggagg agcggggatg gtaatgactc ctcaacctat atatgacaca
    26821 tataagcata taataacaac tcataatata aataacccaa gtgtaattta tcttactcca
    26881 aaaggtaagg tatacaatca atctatggca aagcagatgt ctttaaaaga agatataata
    26941 ctactatgtg gtcattatga aggaatagat gagagaatca ttgatttaat agttactgat
    27001 gaaatttcaa ttggagatta tgtattaact gggggagagc tcccagcact tataatgata
    27061 gattctatat cgagattaat accaggtgta ttaaaccaag aagaatcatt tgaagaagaa
    27121 tcatttaaag acaacttatt ggaatatcct cattacacta gacctagaga ttttgaagga
    27181 ttaaaagtac cagaagtgct tttatcaggg aatcataaga agatagatga gtggagaaga
    27241 gaagaatcta taaggataac caaagaaaga cgatttgatt tatataaaaa gtctaatgaa
    27301 aaataaaaat ataatgaaaa attaatatat atgtatacaa taaagtacct ataaatggaa
    27361 ttaaaaacat aaaagtgctt gtaataacta ttgaagtata gtataatata aaatgttgaa
    27421 aatacgggcg ttcctctgtt tacactggtc gggtagttaa gaacgtctat gatatctagg
    27481 aggaagaaag atgaatgaaa tgctaagagc aattgagcaa gaacaattaa aaaatgaagt
    27541 tcctaatttt ggacctgggg acacagttaa agtacacgtt agaattatag aaggaaaaag
    27601 agaaagaata caagtattcg aaggtgtagt attaaagaga caaggtggag gagcaagaga
    27661 aactttcaca gttagaaaaa tgtctttcaa tgttggtgta gaaagaactt tcccagttca
    27721 ctctccaaaa atagaaaaaa tagaagttac tagaaaaggt aaagtaagaa gagctaaact
    27781 aaactactta agaggtagag taggtaaagc tgctaagata aaagaagcta gaaataaata
    27841 attaaaaact ttacttataa atggggggct gatttatcag tcctctttct attttaatga
    27901 aaattacagc aaataattat actagaaata aatagaaata tttgttgaaa atatacatta
    27961 tttatctatg aatttatagc ttttaaaatg aaaaataaaa ttggtaaata ttgcattata
    28021 ttttgtaaca atattaaaaa taagagaaca gtattatgta aagtatgacg ttaaaaagat
    28081 gacaatatta tagtttgtta agatagattt tttaagtgga attaggatat aataatataa
    28141 tattaataag gagtgataca tgtgtcaaat gaatacgaag agtatcttat gaatgacaat
    28201 ctacatataa actggtatcc aggtcatatg aaaaaaacta aggagttagt aaaaaataac
    28261 ttaaaattga ttgatgtagt aattgaactt ttggatgcta gaatcccgtt tagtagtaaa
    28321 aatccagaca tagacaggct tgtaggagat aagccaagag ttgtcgtact taataagagt
    28381 gatatggcag atagggataa attgaatcaa tggattgaat actataagaa aattaatatc
    28441 aaagctatac cagtagatac aataaaaggc gttggtataa ataagataat cgaagaatgt
    28501 aaaaatgtaa ctagagaaaa aatgagttct ttaaaagaca aagggagaaa agaaagagct
    28561 atacgaataa tgatagttgg agttccaaac gttggtaaat cgtctcttat aaacaaatta
    28621 acaggtagaa aaagcactca aactggagat aagccaggag taacgaaagg gaaacaatgg
    28681 gttagattaa agggaaatct tgaactttta gatacacctg gaatactttg gcctaagttt
    28741 gaagaccaag aagttgcatt aaatttagca tttagtagag ctataaagga tgagatttta
    28801 gatactgaaa ctttggcttt aagacttata gaaaaactta tgaaaataga acctgagaag
    28861 ttgaaagcca gatataagtt agattgtcta ggagaaactc caattgaaac tatggatatg
    28921 attggccata aaagagggtt tataacaggt aaaaaagaac tagattatac acgcatagcc
    28981 acaactgtat taaatgaatt tagagatgga aaaataggaa atataacatt ggaagttcca
    29041 gaaaacgtta aaagatagat tttaaaacaa aatcaaaaat ttaatgttaa aaatttaaaa
    29101 aagcctttta gcaaaggctt ttttattttt ttgaaatata gacaaatatc tccatataaa
    29161 agtataaatt aggttagaaa acctttaaaa atattaattt aagacaaata tacctaatat
    29221 tttgaaaatt aaaatgagtg tgattattta aaattttagc atattgactt gcttgtttcg
    29281 tataatatat aataagcaca aataaataca atatattaaa aatttaattt atttaatttt
    29341 attaatttaa taataagttc ttattgttta attcaactta cttatgcaag cgtaaacaat
    29401 cgagacattt tattaattta ataaggttaa aaagggggat tttataatgg gtaagaccaa
    29461 ggatgttata gtatttggat ttgcgttatt tgcaatgttc tttggagcag gtaacttaat
    29521 atttccacct tacttgggaa taattacagg tccagaatgg ttaattgcct tcttaggatt
    29581 tacgtttgct gatgctggat tggcacttct agcagtaatg gctacagcta aattcgatgg
    29641 aaacgtagtt gaaatgttta aaagatgtgg tatgaagtta ggaattctta taggttgtgc
    29701 agatatttta tgtataggcc cattcttagc tataccaaga acaggtgcaa caacttatga
    29761 aatgggtata atgcctttgt ttggaacttc aattccagtg ttattattct gtatactttt
    29821 ttttgcgatt tcatatgtac taacaataag accttctaag gtcgtagata tagttggaca
    29881 gtttttaact ccagctcttc taatagcttt agcatttata attataaaag gtattatatc
    29941 acctcttgga gatatagtag ataaacctat gatacctaat gtatttgcag aaggtatagg
    30001 tcaaggatat cagacaatgg atgcttttgc agcaatagca cttgcatcag tgctaatagt
    30061 atctttaaat gataaaggat attctactat tagtgacaag ttgaaaatga ttggtaaggc
    30121 gggtgttctt gcttgtggag gattagctct agtttatgga ggattatgtt tccttggggc
    30181 aactgtatca acaatgtatg gaacagatgc agtacaatca caagtaatag taaatataac
    30241 tgaaggattg cttggaaatg ttgggaaagc gattttagca gtagtagtat cattagcatg
    30301 tttaactaca tctataggtc ttacatctgc cacaggtcaa tatttctcta gacttacaaa
    30361 aggtaaattg agttatgaaa aaatagtatt agctgtatct gtattcagtg cagtagtagc
    30421 atcttttggt gttggaacta taataaagat agcatctcct atactaagta tagtttatcc
    30481 accatcaatt gttttaataa ttttagcttt cttcaatgaa aaaattaaga atgataatgt
    30541 atacaaagga gcagtatata tgtcattgct tgtaagtata ctaacagtta tatctagtta
    30601 tggagtagct gttccagtag taaattcttt acctcttaat tcattaggat ttaactgggt
    30661 ggtgccagtt ataatagctg gaataattgg taattttata ccatcaaaga gtcaatctaa
    30721 tacacttgga acaaactaag ttttgtttaa ttaaaatata atcaattgta aataaatgag
    30781 ttaactaaaa gtaaaaggag ttatttgtac aaataactcc ttttattttt agattctata
    30841 tttaattatt tgtatttaat atggaaaaag tataagaaaa tatcaaaaaa atatatggtt
    30901 tattttttaa caataataga gattaaaaaa gaattttaga gtaattttat aaatttaagt
    30961 atacatatta aatgattttt acaaaaatat aatataaata aaattgtgac aataataaaa
    31021 taataaaaca aaatttaaga catatgatta tataaatgta ttaaataaat gagtaaattg
    31081 ttttcattga gagatatatt aagaattttt agttaattat gacatataag tatgtaaacg
    31141 tgaatactag caactgcaaa gtttaagtaa gttggaagtt agagagtaat tgttatgaag
    31201 aaaaataagt tgataaatca taataaggaa ttttcagaaa aaatggtttt aagagtaaaa
    31261 aacaagaggc aaatctacgt aagtagaata aaaattgaat aaagttaact gtcaatttag
    31321 caaaataaat acaaaatact acaagaatta acgtaaatag gtgttatgat aaaaggaaaa
    31381 cgatttttta agaatcataa ttttgaaaat taaaaaaatt aaaaatgcta ttgactgctt
    31441 ttttttcaga ttatataata aacacaaaat atttaaaatt taaattgaat taaaaagatt
    31501 atatgaatgt aaaaaaggag agtgatatat acagtatata aagcaataca acttaataat
    31561 aaatcgaata atctaaaaag tcttaatatt ttaattattc ggaatagtta attttatcaa
    31621 gaaaaattag agaaaaaaca aaaaaccaac tatgtttaaa gtatacaggt tgattttgtt
    31681 taattaagaa agttgtatta aatattgtga agattttata aattatgaaa cataattgac
    31741 aaatttaagt caaaaatgta taattaaata aaatctcgtc aaaaggtttt catttaatta
    31801 agagattgga cttatttttt agtaaaaggt agtaaaattc aaatgggggt gctttaaatg
    31861 ggtgagaaac aaatcaattt taaagatgta attgtaattg gatttgcact atttgcaatg
    31921 ttttttggtg cagggaactt aatcttccct ccatatctag gagttttatc tggaagtagt
    31981 tggctagtag ctttcatagg attccttttt gcagatggtg gtttggcatt attagcagtt
    32041 atagcagcaa ctaagttcaa tggagacaca tcgaagatgt tctcaagagc aggcaaagga
    32101 ttaagtattg cattaggatg tgcaatggta atctgtatag ggccactttt agcaatacct
    32161 agaacagcag caacaactta tgaaatgggt atattaccta caataggttc tggaataagc
    32221 ccagtaatat tctctatagt attctttgct ctagtattgg ttttaacaat aagaccatca
    32281 aaagttgtag atatagttgg gtcaatatta actccagctt tacttatagc tttggcagta
    32341 ttaatagtta aaggtatcgt atctccatta ggagaaataa gagacagttc tttaatacaa
    32401 aatgtatttg cagaaggtat aactcaaggt tatcaaacaa tggatgcatt ggcagctagt
    32461 gtatttgcat caattataat catgtcagta atagctaaag gttatacagg tgagaaagaa
    32521 aagatgaaag ccacaataag tgcaggtgta attgcagtaa taggaatggc attagtttat
    32581 ggtggattat gttatcttgg agcaactgtg tctcaacaat atggacaaga tgttcaacaa
    32641 acagctttaa tagttgcaat aacagcagct ttacttggaa ctacaggtaa aattttattg
    32701 gctattatag ttgcattagc atgtttaaca acagctatag gtctttcttc agcagctggt
    32761 caatatttct caacacttac agatggaaaa ttaaagtatg agcatatagt tatagtagtt
    32821 tgtgtattta gtgcaatcat atcaaacttt ggagtaagta caataataca attctcttct
    32881 cctatactaa gtatggtata tccagcaact ataactctag ttatactagc attatttagt
    32941 aataaaatta aaaatgacaa cgtgttcaaa tgtgctgcat acatggcatt attagtaagt
    33001 gtattaacag ttgcaacaag ttttggtgta aaaattcctc tagttaatag cttaccattt
    33061 gcttcattag gatttaactg gatagttcca gttgtaatag caggaataat aggaaacttt
    33121 attccatcta aaagcagtaa aactgcataa taataaaaac taattgataa ttatggaatt
    33181 gcctttaaat tatataggca attccttttt atatttaaaa gaattattaa attattgtag
    33241 ataaaagaac attattaatc ctatttgata aatttaaaaa tttatttttg gagtagtatg
    33301 atttataaag ataataaaat aaaaaagatt catttataat tataaataaa attaaattat
    33361 atattataag tgtttagtat taatataaaa acactaatac atatttt
//
LOCUS       DAFAZV010000047        32034 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFAZV010000047 DAFAZV010000000
VERSION     DAFAZV010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 32034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32034
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.047"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            396..1562
                     /locus_tag="KOU88_003033"
     CDS             396..1562
                     /locus_tag="KOU88_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase family glycosylhydrolase"
                     /protein_id="HBK3212889.1"
                     /translation="MYIKGVNLGGWLVLEKWMTSSLFEGTEAEDEYYLPRQLSREAYE
                     SRIKTHRSEYITERDFATIKSMGFNSVRIPVPYFIFGDCEPFIGCVKELDKAFAWADK
                     YGLSILIDLHTVPGSQNGFDNGGISGICSWSQNPEYVAFTLNVLERLAKRYGMRHELY
                     GIQILNEPITERMWNIMNVPNRFKAVDKEMARGSKPNSLEFLRDFYIKAYKVMRPYMR
                     EENVIVFHDAFELKAWKDFMREEEFKNVVLDTHQYLMLAEADGCEQSIDSYLKYIREN
                     YAKDILQMQKYFPVICGEWSLFNSYACGIDTNGGQSPLNGIESNIDKLSKDDKRELYR
                     KIAKAQLDAWRNGSGHYYWNYKLLLDTVNEEGWIGWDSWDLGKCVAQEWYPIEY"
     gene            1584..3230
                     /locus_tag="KOU88_003034"
     CDS             1584..3230
                     /locus_tag="KOU88_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBK3212890.1"
                     /translation="MIKNPILPGFNPDPCICRKGDDYYLVVSSFEWFPGIPVYHSKDL
                     KNWELYTHILTDETKIDLKKLPSSKGIWAPCLTYCEEEDLFYIVYGIMNSMNARYFDV
                     DNYLITSKDIKGEWSEPVYLHSSGFDASIFHDDDGKKWIASLDWETREGYEKPGVICL
                     VEYCTKKKEIVGYPKRIWSGGTDRGCIEAPHITKRGDYYYIMCAEGGTGYGHSVTMGR
                     AKNIWGPYEKDSMNPIVTSIPGDFYERHDPDHLKPKYYNPESKLQKSGHGSYIETTSG
                     EVYLVHLTSRPFVPELRCTLGRETAIQKMRWTKDNWLRMEDESNLAKEYVSESKLEEH
                     LVSSIPSFDDFDSNELGLQYYAPRISPLSFADVKSRPGYVRIRGQESRTSLNKVSILA
                     RKLTSVYARITTKMEFYPEVHQHSAGLIMYYDNMNYINLRKYYSETLGQSALSIIHLE
                     NGEKTEFLNTRIPIKDIPIYLRLYIQGRKSYFEWSYDEKNYQRIGKVFDTTKFSDEYC
                     KYGEFTGTFIGLTCADRVKHKHYADFDFFEYIVDESKDVD"
     gene            3327..4700
                     /locus_tag="KOU88_003035"
     CDS             3327..4700
                     /locus_tag="KOU88_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3212891.1"
                     /translation="MNTEVNVKATTIRYEKISFFERISYGCGDLGCNIIYSAMSAFLL
                     FYYTNYADVSAAAVGSIMLVSRILDGFSDLTMGIIVDRTKSKYGKARPWILRMAIPFA
                     IAAVLLFSVPSNLGITSKLIYIFITYNLVSTVIYTAINVPYATLNSLITQNQYERGVL
                     SIFRMILATCGTLLINGLTLPLVEYFGNNLSAWAKTFFVFGIASIMVFFITFTGTKER
                     VKAVKQDRNEVIPFKIGIKSLFRNKYWIQITLCLVCIFIVFAINGGSSVYYAKFILGD
                     EKLFGSINMVSNISQIIAMFMVAPFIKKFGKRNVLIVGSIILISSNVMFIIVGQDYIG
                     VIFSSAIKGIGSAGIASTMFAIVSDTIEYGEWKTGYRTEGLINSASSFGFKVGNGLGS
                     AILGAVLSIGGYVGTSATQSDLAIVSIKVCFIYLPIFITILQIIIMSFYKLDKEYSTI
                     LNELNTK"
     gene            5145..6098
                     /locus_tag="KOU88_003036"
     CDS             5145..6098
                     /locus_tag="KOU88_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBK3212892.1"
                     /translation="MKKIGDLRLMMKCCSLYYEDNLNQQEIANQLGISRPTISRILKE
                     AFEQGIVKIQIVDVLKNDYQKIERSLERKYKLKEVIVVDDKQDALTQKQELARAVSEY
                     LTRVVKENDIIGVSIGTTLKEIPRYVEKSNCKNVTFIPLLGGIGDNEIDIHANQIAVS
                     LARAFGGDFKLLHAPAVMSDLSTKEKLCKDEKIKEVLDLIDKTTIAIVGIGNPMSLNS
                     TIMASGYMNEADIEDLKKYNSIGAICLQAFDKEGKTSILEFNQRVLGVKLEDLKKIKR
                     TIGVASGDEKIEAIKASLKAKFINSLAINHSLALKLLEDCD"
     gene            6136..7098
                     /locus_tag="KOU88_003037"
     CDS             6136..7098
                     /locus_tag="KOU88_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HBK3212893.1"
                     /translation="MSISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQ
                     EASSVAAVMALEKGDLVSLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI
                     ADIESGNLGANGVVGGGLTIAPGAALTQQYKKTGKIVLCSFGDGASNEGTFHEGINLS
                     SIWKLPIIFYCENNLYGMSTSIKRHMNIESIATRAASYGIEGISIDGYNPIEVYETVQ
                     KAAEKCRRGEGPVLIESRTYRWLGHSKSDANVYRTKEEIESWKAKDPIEFLKNYLIEN
                     NLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVYAD"
     gene            7123..8109
                     /locus_tag="KOU88_003038"
     CDS             7123..8109
                     /locus_tag="KOU88_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBK3212894.1"
                     /translation="MSTRELTYAQAIKEAMSEEMRRDENVIFMGEDIGIYGGAFGVSV
                     GMIDEFGPERVRDTPISEAAIAGAAAGAAATGLRPIMEVMFMDFVTISMDAIVNQAAK
                     MRYMFGGKAQVPMVVRCPGGSGTGSAEQHSQSLEAWFCHVPGVKVVAPSTPADAKGLL
                     KAAIRDNNPVIFVENKLLYRKKGFVPEDDYVIEIGKADIKREGTDVTVITYGRMLQSV
                     EEAAETLSKENINVEIIDLRTLYPLDKETIVKSVCKTGRVLICHEAAKTGGLGGEISA
                     LITESESFDYLDAPVKRICGKDVPIPYNPELEKAVVPRVDEIEEAIKSLIVR"
     gene            8122..9168
                     /locus_tag="KOU88_003039"
     CDS             8122..9168
                     /locus_tag="KOU88_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HBK3212895.1"
                     /translation="MVANKIKATPAARSQARKDNIKLDRLIGSGENGRIHLVDVLNYL
                     KDNKANTTPLARRIAEDLNIDLETIVGTGYNGKIRKCDVEKLTGKETIVSTNTSKSSE
                     KKELKIENENSRMFNTVEGIFEKPNPMRATVAKRMSESYFSAPVFTFNIEVDATELKV
                     LRAKLIDTVKESTGVKLTMTDLIVMAVSKILPNHQALNSAWTDEGIFRYKDVNIAIAV
                     GLDEGLYVPVVKNANKKSLKEIAKESKELAEKVKTGKLMPADQEGNTFTISNVGMYGI
                     TTFTPIINMPSSAILGVGATQDKFVPVNGEAKIKPIMNLSLTSDHRVIDGTVAAKFLK
                     DLKELLENPLSMLV"
     gene            9335..11065
                     /gene="lpdA"
                     /locus_tag="KOU88_003040"
     CDS             9335..11065
                     /gene="lpdA"
                     /locus_tag="KOU88_003040"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBK3212896.1"
                     /translation="MSVEVIMPKAGVAMEEGTIVSWLKQEGEEVKIGEPILEITTDKV
                     NMEIESEGEGTLAVIIHKEEGEVLPVFTVIGVIAEKGENQEEVKAKYLSGNVSKEDIV
                     EENQNIEFKEEKINKKECNHDYDVVVIGGGPGGYLSALKAALLGGRVALVEENILGGT
                     CLNRGCIPTKTYIKTAEILEEIDQLSKRGVKVTVDKEQDIKKAIKYKNRVVKKLTAGV
                     GGLLKSRDVDVFNLKASVKEEHKVILSDGKVLDTENIIIATGSKVRILPIKGIESNLI
                     ITSTEALDLETVPEELVIIGGGVIGCEFAEIFNSRGSKVTIVEMEDRVIPRMDKELSE
                     SLKYSLSKKGINVLTKKKVSEFKEEGNNILVCIEGEEPIKADLCLYAIGREANLSGIE
                     DLDIKIDKGSIVVNSKMETSIPSIYAVGDVTGGVMLAHAAFKMGEVAASNALGVNKEV
                     DLGALPSCVYTIPEVASVGITEEDARKKYNVKVGKFNFAGNGRALASGQEQGYVKVVA
                     DAKYGEILGIHMFGCGVAELINHAASFKALEIPTDEASELIFGHPCTSEALMEALADV
                     NGECLHLPKK"
     gene            11483..14431
                     /locus_tag="KOU88_003041"
     CDS             11483..14431
                     /locus_tag="KOU88_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3212897.1"
                     /translation="MRQRIKNLIENEDKKNPLTDEAISSRLNIRREDVTFLRNELKIE
                     DSRQRRKVVLIKAIKDILKEEKTINKNDITRRLNSIGFTVSRFTVIQYLKEIQDSGDL
                     KLDKESDDKKEEIINNRENKDIAFDKLIGSSGSLSTIIKLAKAAILYPPHGLHTIIMG
                     PTGVGKSELAECMYKFAVESSRFPKNAPFIVFNAADYSENPQLLLSQLFGHVKGAFTG
                     ADENKEGLVSKADGGILFIDEIHRLPHEGQEILFQLIDKGMVRKLGETRLTHKIDVMI
                     ISATSEPIDSHLLNTFKRRIPVTIEIPELVARPLNERFDIINNFFLIEAQRMGANIHI
                     KSDVLKALMLYDCIGNVGQLRSDIQVACARGLLNQLTNKLKEVNISISDVPGYVKQGL
                     IKIRNCRGKIENYVDGDLIIDSNLQGEIEKKNEDIYTFPDEIYKLTERRHIDLLEQGL
                     DFDVINRIIGGELESCIQKYIKQVKKVSISNNLPDISPIVGKYIVELTYEVIKIASQY
                     LSSLEPNLHLCLAVHLKAAFERLKEGKVISNAHLKEIIGNYPVEYSVAEKVAQYLKER
                     YNINLPKEEIGIIAIYFKMSSRRDMSEQKKIGVLLMAHGRVASSVCEVTNKLLGINHA
                     RYLDMPFEKKPEEMIEEATTIIKDIDEGRGVIILVDMGSLSYFGDIISGKTGINIRTI
                     SRFDTLLSIEVIRRAVLPDLTIDEIVDEVKGIEPQVKEKVSKCNNTKVDFRKPIILTL
                     CITGLGGACKIKKILEENIKSITEKVDIEPIGMIEYPSLDLEIKQISNDKNVIAIVGT
                     IDPQIANIPFFSLVDINDKAKLNQINNLIDTNQIGETNKKYELSDLIHKEDIFVDLQV
                     KSKEEVLKYMSKKLREKGYVTKNFYKKVVERDNLFPTELSDEIAIPHTDGIDVIRPAI
                     SIAILKKPIVWSKSKVKIILLLAVDQKCFNPLSTLLSFIETDEFKKIKNIKDRDFIRE
                     MILDGVNENN"
     gene            14409..14873
                     /locus_tag="KOU88_003042"
     CDS             14409..14873
                     /locus_tag="KOU88_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3212898.1"
                     /translation="MESMKIISSNLIFKNIEVSNNEDALKFLGQRLFDEQYVKESYIQ
                     AVVAREKKYATGLPTEIYGVAIPHTDIVHVNEPGIAIGILNKPVKFIMMGTDDTEIDV
                     KVVFMLAVKEPQEQLQLLEKLMTIFQDKNILNNIVDLSEESVSDLLNSKLKN"
     gene            14953..15255
                     /locus_tag="KOU88_003043"
     CDS             14953..15255
                     /locus_tag="KOU88_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3212899.1"
                     /translation="MGVTNVAKKILVACGTGVCTSTIAINKLKKALQDIGKLDMVNIT
                     QCKVVEVASKAPDYDLIICTTQVSSSIKTPVINGLPFLTGVGMDKLINDVLEELEL"
     gene            15317..16681
                     /locus_tag="KOU88_003044"
     CDS             15317..16681
                     /locus_tag="KOU88_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425524.1"
                     /note="with GatAB forms a phosphoenolpyruvate-dependent
                     sugar phosphotransferase transporter for galactitol;
                     subunit IIC forms the translocation channel and contains
                     the substrate binding site; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBK3212900.1"
                     /translation="MEGLYMEILNFIVGLGAQVMMPIIICIFGLILGTKLGKSLRAGL
                     TVGVGFIGLNTIIALLTDNLGPATQQMVKNLGLSLSIIDVGWPAASAIAFASTVGALI
                     IPIGLVVNIVMLITNTTQTVDVDIWDYWHFAFTGALVAGATQSVMWGVFAAVANMVIV
                     LVMADLTAPGIEEYLGMPGISLPHGFTQAFVPIAIVVNKLLDLIPGINKIEINADTLQ
                     KKFGLFGEPLIMGSVIGVIIGIAAKYDIKGILQLGVTMGAVLILIPKMAALLMEGLLP
                     VSEAAQEFIEKRFKNRGKIYIGLDSAVGIGHPVTLSVALVLVPLTILIAAILPGNKVL
                     PFADLAVIPFALVLIVPITKGNVFRTLIIGIIIITSGLLIATNLAPLFTQMALNASFK
                     MPEGATMISSICDGANPLSWVFVKVMNYKVIGGVVFGVIALGMAIYNRNRIINENKKL
                     SIEE"
     gene            16716..17189
                     /locus_tag="KOU88_003045"
     CDS             16716..17189
                     /locus_tag="KOU88_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212901.1"
                     /translation="MKKYKYDSKRYLLSVTIPGFFMILILIYALFNNYTNFNLNIYSL
                     LIIVCTYGIFNTFISSSNPKKIIIDSKCIHFTSFMTTHKYEIKDIEKIRIREFYNKKI
                     YVKINDGNLFKGRYWIRTNMFNNSIALYSYFIELEECLYPDSLKFRNKKFENKNI"
     gene            17361..18011
                     /locus_tag="KOU88_003046"
     CDS             17361..18011
                     /locus_tag="KOU88_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBK3212902.1"
                     /translation="MLLEKLRKEVLQASLDLLNYNLVTLTGGNVSGRDEQTGYIAITP
                     SGMDYRNLTPSDIVIVDVDGNIIDGKWKASVDLSDHLYIYKHREGINSIIHTHSTYSS
                     CFAILNEPIECASTTLANEVGGSVPVAKFSPPTSKKMGKCVIEAIGDKRACLLANHGV
                     IAVGPSVGHALTAAVMLEDSAKVYYLAKSIGTPVLLPDEEIQRARDVFFNVYGQDK"
     gene            18185..19117
                     /locus_tag="KOU88_003047"
     CDS             18185..19117
                     /locus_tag="KOU88_003047"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBK3212903.1"
                     /translation="MYYLLNKSTNPYFNLALEEYLFLNDKYNDDIIIIWRNEESIFIG
                     KNQNPYQEVYYDVIEKGEIPILRRISGGGTVYHDLGNINMSFIQKNRQLHEIDFLEHT
                     KFMQKMLSTLGLDVSITERKDLFLNGKKISGSAQSIKRKNSLYHGTLLYDSDLNKLTK
                     YLNSNKATESNATKSVSSKVTNIKFLLEKDINYFLDYCVEYLKSNIKNIKELELDEED
                     IKSVYNIGEDKYKKIEWTYGKTPKFQVVLPFNNESKINIHVNRWKVSKFFISYDDNVI
                     NMDKLLDLNFFKEEIKESILENYPHYIDLINLIF"
     gene            19391..20104
                     /gene="ispD"
                     /locus_tag="KOU88_003048"
     CDS             19391..20104
                     /gene="ispD"
                     /locus_tag="KOU88_003048"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBK3212904.1"
                     /translation="MYSVIIVAAGSGRRMNLDINKQFIKLREKEIIAHTIQVFYENIN
                     IDEIVVCIKKEEEDFFKENIINKYNFKNIKIAYGGKERQDSIYNGLKKLDENCDIVLI
                     HDGARPFVDHRIINESIKVAKEKKAVVVGVPVSDTIKIVSDGTVQETPERNLLWAAQT
                     PQTFEYNLIIDAYEQAYKNNYYGTDDSMLVENIGQSVTMVMGSYENIKITSPEDLNIA
                     EQILNMEKRDEVNSRRRII"
     gene            20101..20586
                     /locus_tag="KOU88_003049"
     CDS             20101..20586
                     /locus_tag="KOU88_003049"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBK3212905.1"
                     /translation="MRIGLGYDVHKLTEDRKLIIGGVEIPHDKGLLGHSDADVLIHAI
                     MDSILGALALGDIGKHFPDTDEEYKGADSMKLLEHVYNLITSKGYKIGNIDSTIIAQS
                     PKMAPYIESMRSNISKVLNTDIDNINIKATTEEGLGFTGAKQGIASQSICLLLLTSQN
                     N"
     misc_binding    20681..20889
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20953..22668
                     /locus_tag="KOU88_003050"
     CDS             20953..22668
                     /locus_tag="KOU88_003050"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBK3212906.1"
                     /translation="MKMSKMFMPTLKEIPADAEITSHQLMVRSGMIKKMTSGVYNQLP
                     MGLRVFKKIEQIIREELNKKDCQEILCAALLPSELWKESGRWTAMGEEMFRLKDRTER
                     EYCLGPTHEEAFTDIIRQEITSYKQLPLNLYQIQVKYRDERRPRFGVMRTKTFTMKDA
                     YSFDVDDKGLDKSYQDMFDAYVSIFDRCGLENSPVQADSGAIGGSTSAEFMVKSEVGE
                     DEVVFCSGCDYAANVERAESCNLASQKEEMKELEEVHTPGAATIKELEEFLKTSPDKF
                     AKTLVYEADGKTVVVVVRGDREVNEIKVSNAIGSVIEFALATDDVVRKVTNAEVGFAG
                     PIGINADYVFIDKEIVEQRNIVVGANKTEYHIKNANYGRDFEGIVGDFRNVQEGDKCI
                     VCGKPLEIARGVEVGHIFKLGTKYSESMNANFIDKDGKSKPIVMGCYGIGVERTAAAI
                     IEQHNDEKGIIWPLSVAPYHVVIVPANMKNEEQISIAENIYNDLQAMGVEVLLDDRDE
                     RIGVKFNDSELIGIPMRITVGKNINEGKVEFKLRHKEDKEIIDIEEINEKVKAEFIRN
                     NVRLG"
     gene            22790..24235
                     /locus_tag="KOU88_003051"
     CDS             22790..24235
                     /locus_tag="KOU88_003051"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBK3212907.1"
                     /translation="MAKNEKQFVEEITKMEDDFPQWYTDVITKTDLVDYAPVKGFMVV
                     KPYGYALWEKMQEFMDKKFKETGHKNCYFPLLIPESLLNKEAEHVEGFAPEVAWVTHG
                     GNKKLEERLCVRPTSETIICTMYAKWLKSYRELPYLYNQWCSVVRWEKSTRPFLRTSE
                     FLWQEGHTLHETAEEAQEETIQQLEVYKALCEELLAMPVVAGQKSESEKFAGGERTYT
                     IEAMMHDGKALQSGTSHFLGQHFTKAFDITFADREGNLANPYHTSWGASTRLIGGLIM
                     THSDNRGLVLPPRVAPIQVVIVPIAAKKGNVMETVDKIYADLKAKGVAVEVDDRDNYT
                     TGWKFNEWEMKGVPVRVEIGPKDIENNQAMVFRRDTLEKDSMPLEGLADAICDLFDVI
                     HNDMFEKARKHREDNTSIVENMDEFRKALEEKPGFIKTMWCGDAECEAKIKEETGATI
                     RCLPFEQENLGHKCVYCGKEADSMVVMAKAY"
     gene            24673..26154
                     /locus_tag="KOU88_003052"
     CDS             24673..26154
                     /locus_tag="KOU88_003052"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBK3212908.1"
                     /translation="MNVRVRFAPSPTGFVHIGSLRTALYNYLFAKKMGGEYILRVEDT
                     DQSRLVEGAIENMLNAMKWAGVNHSEGVILDDSGKVVQKGEYGPYIQSQRLDIYQEYI
                     KQLLDSGKAYYCFCTKERLDEVRDAQRAAGETAKYDGHCKNLSKEEVEANIKAGIPYV
                     IRLRLPENHTIKFTDLVRGDMEFNTNDLDDQVLMKTDGFPTYHFAVVVDDYLMKITHV
                     IRGEEWVSSTPKHVYLYEAFGWEAPVFVHLPNILNKEKKKLSKRQGDVAVEDFKKKGY
                     LPEGLVNYVALVGWSPEDNQELFTMEELEKAFSVERVSKSGGVFDTEKLNWVNQHYIK
                     DGDDAYLTDLAIPFLIEDGFITEEEATNKYDFLKSMISVLKEKLQYVKEVTEHASIFF
                     GDKIEVETEEGREFLRLEHIPTLIDALREKIEKTEVLNAEFVQAMLKEIQKEYKIKGK
                     NLFMGSRIILTGQMHGPDLPKVMEVLGKETCLNRIAYVKNNIL"
     gene            26375..26530
                     /locus_tag="KOU88_003053"
     CDS             26375..26530
                     /locus_tag="KOU88_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212909.1"
                     /translation="MYSNIDDVKKELKELCLEYVTILEKLKDEKMITEETFEKCSSQK
                     KIFLEEQ"
     gene            26675..28072
                     /locus_tag="KOU88_003054"
     CDS             26675..28072
                     /locus_tag="KOU88_003054"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBK3212910.1"
                     /translation="MKVYNTLTRTKEEFVPLEEGKVKMYVCGPTVYNYIHIGNARPFI
                     IFDTLRRYLEYRGYDVTYVQNFTDVDDKIINRSHEEGISPEEVAAKYIKEYFVDCDGL
                     GIKRATVHPQVTDNIQQIIEFIKELEDKGYAYAVNGDVYFDTNKFEGYGKLSGQKQED
                     LEAGARIEVNDQKRHPMDFVLWKAKKEGEPGWDSPWGEGRPGWHIECSVMSKRYLGET
                     IDIHAGGQDLTFPHHENEIAQSEARSGKTFSKYWMHNGYININDEKMSKSKGNFFTVR
                     DISKLYDLEIVRFFMLSAHYRNPVNFSDEMLNQAKAGLERLYNTKEKLEFTLSNLVES
                     PLTEKEVELVKELDDFRQKFIDAMDDDVNTADAVSVIFELAKLINSNVDENSSLEFAK
                     KCLDEFNELTGVLNIVNKKKDTVLDKDIEELIQKRTDAKKNKEFQLADDIRQQLLGMG
                     IVLEDTRQGVKWKRI"
     gene            28057..28470
                     /locus_tag="KOU88_003055"
     CDS             28057..28470
                     /locus_tag="KOU88_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBK3212911.1"
                     /translation="MEKDIKMEKTELVTMSPLVLAYLGDTVYETYIREYLIRQNTQRK
                     VNDLHKLAIKYVKAKAQATIIHEIEIELTEEESKIYKRGRNQKSNTSPKNADIIDYKH
                     ATGFEALVGYLYLNNEIERLQYIINKGIKIIERDM"
     gene            28576..29334
                     /locus_tag="KOU88_003056"
     CDS             28576..29334
                     /locus_tag="KOU88_003056"
                     /EC_number="2.1.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent thymidylate synthase"
                     /protein_id="HBK3212912.1"
                     /translation="MKVKLISHTPEPEKVIAMAAKLCYSPVGTDEIEKDLTDESIEKF
                     LNMLLSIGHGSILEHASFTFSIEGISRACSHQIVRHRIASFSQQSQRYVKLEQFEYII
                     PPEIEKIEKAKELFIDSMKKDQENYDKLVEILFENHYNDLIKNGKNEKTAKRQAEKKA
                     IEDARYVFPNACETKMVFTINARSLFNFFEHRCCERAQWEIRNLAVEMLKEVKKVAPI
                     LFKKTGPSCVNGSCPEGTMTCGDIVQVREKFKAL"
     gene            29347..30084
                     /gene="rlmB"
                     /locus_tag="KOU88_003057"
     CDS             29347..30084
                     /gene="rlmB"
                     /locus_tag="KOU88_003057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBK3212913.1"
                     /translation="MASIEGRNPVIEAIKSDREIDKILIANSAKEGSIKKIIGMAKDK
                     NIIIQYVDKHKLDEVSTSHSHQGVIAYASEYKYYELDELIDLAKNKDEDPFFIILDEI
                     TDPHNLGSIIRTADAVGAHGVIIPKRRSVHITPVVAKASAGAVEYMPVCKVTNIVNTI
                     KRLKEEGLWIAAADMDGETFYKQNLTGPLGVVIGSEGFGISRLVKQNCDFIVKMPMIG
                     NVTSLNASVAGGILLYEIFRQRLDKSK"
     gene            30087..30614
                     /locus_tag="KOU88_003058"
     CDS             30087..30614
                     /locus_tag="KOU88_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBK3212914.1"
                     /translation="MKKNINHYLIIDGYNIINAWDNLKELAKEDLEDSREKLIDDIIE
                     FSEFMGYKTIIVFDAYNVKNSREKVEKRKHITIVYTREHQTADSYIEKFITSLSKYDD
                     VKVATNDYAEQQMILGKGATRMSARELKLELDRSKNKMKEKNIGLRKKIQRNWLEERL
                     DKETLSKLENIRRKR"
     gene            30679..31326
                     /gene="sigH"
                     /locus_tag="KOU88_003059"
     CDS             30679..31326
                     /gene="sigH"
                     /locus_tag="KOU88_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sporulation sigma factor SigH"
                     /protein_id="HBK3212915.1"
                     /translation="MLVAKEKSYELVDNCQQDEYNIVLRASEGDKIALEYIITKYRNF
                     VKAKAKSYFLIGADKEDIIQEGMIGLYKAVRDFDGSKTNSFKCFAEICITRQIITAIK
                     TATRQKHIPLNSYVSLNKPIYDEESDRTLLDIIATSIVTDPEELIISKEELKNIESKM
                     NELLSDLELEVLELYLNGKSYQFIADKLKRDVKSIDNALQRVKRKLEKHLENRND"
     gene            31400..>32034
                     /locus_tag="KOU88_003060"
     CDS             31400..>32034
                     /locus_tag="KOU88_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBK3212916.1"
                     /translation="MAKAKYERTKPHVNIGTIGHVDHGKTTLTAAITKTLYDRYQLGE
                     AVDFANIDKAPEERERGITISTAHVEYETPNRHYAHVDCPGHADYVKNMITGAAQMDG
                     AILVCSATDGPMPQTREHILLSRQVGVPYIVVFLNKCDMVDDEELLELVEMEVRDLLT
                     EYDFPGDDTPIVRGSALMALEDPKSEWGDKIVELFEQIDEYIPAPERDTDKP"
BASE COUNT        13035 a         3372 c         6120 g         9507 t
ORIGIN      
        1 ttggataggt tctatcctat ctctacatat aggtttccct atatgctgac tattttaact
       61 actaactcat gactaaagtc acgagtgtgc gtagctattt tttaatcaaa tagtttgaaa
      121 ttaacatcta aattatcaat aggttcaatt atttcatgtg aaaaattatt tctgttcata
      181 ataatatcct ccttataatt ttaaattata aatagtaaat ttataatgtt caatattaaa
      241 aagataatat agactaataa attagataat aaatatactt aagaaaacgg ataaaatcaa
      301 atataataac tgtatattaa aataacttaa aaaaattatt ttattataag tgcaaaatat
      361 acctatttaa ataagataag aggggaggat tttatgtgta tataaaaggt gtaaatttag
      421 gaggttggtt agttttagaa aaatggatga cctcaagttt atttgaaggc acagaagctg
      481 aagatgaata ctatttacca agacagcttt caagagaggc atatgaatct agaattaaga
      541 ctcatcgtag tgaatacatc acagagagag attttgcaac gattaaatct atgggattta
      601 attcagttcg tataccagta ccatacttta tttttggaga ttgtgaacca ttcataggat
      661 gtgttaaaga acttgataaa gcatttgctt gggcagataa gtatgggctt agtatattga
      721 tagacttaca tacagttcca ggaagccaaa atggatttga taatggagga atatcaggta
      781 tatgtagctg gtcacaaaat ccagaatatg tagcgtttac attaaatgta ttagaaagac
      841 ttgcaaaacg ttatgggatg aggcatgaat tgtatggaat ccaaatttta aatgagccta
      901 taacagaaag aatgtggaac ataatgaatg ttccaaatcg gtttaaggct gtagataagg
      961 agatggcaag ggggagtaaa cctaattcat tagagttttt acgtgatttt tatataaaag
     1021 catataaggt aatgcgtcct tatatgagag aggaaaacgt tatagtgttt catgatgcat
     1081 ttgaattaaa agcatggaaa gactttatga gagaggaaga atttaaaaat gttgttctag
     1141 atacacacca atatttgatg ttagctgaag cagatggatg tgaacaaagt attgatagct
     1201 atctcaaata tattagagaa aattatgcta aagatatttt acaaatgcaa aaatattttc
     1261 ctgttatatg tggggagtgg agcttattta attcatatgc ttgtggtata gatacaaatg
     1321 gaggtcaatc acctctaaat gggattgaat caaatataga taaattatca aaagacgata
     1381 aaagagaatt atataggaag atagcaaaag cacagcttga cgcatggaga aatggaagtg
     1441 gtcactacta ttggaattat aagttattac tagatacagt taatgaagaa ggttggatag
     1501 gatgggatag ttgggaccta ggcaaatgtg tagctcaaga atggtatcct atagaatatt
     1561 aaactaaaat tggaggaaaa gatatgatta aaaaccctat acttccaggt tttaatccag
     1621 atccttgtat ttgtagaaag ggagatgatt attatcttgt agtttcatct tttgaatggt
     1681 ttccaggtat acctgtttat cactctaaag acttaaaaaa ttgggagtta tatactcata
     1741 ttttgacaga tgaaacaaaa atagatttga agaagcttcc ttcatctaaa ggaatttggg
     1801 caccttgttt gacttattgt gaagaagaag atttatttta catagtttat ggaattatga
     1861 actctatgaa tgcaagatat tttgatgttg ataattattt aattacatca aaagatataa
     1921 agggagagtg gagtgaacca gtatatctac actcatcagg ttttgatgcg tctatttttc
     1981 atgatgatga tggtaaaaag tggattgcat cattagactg ggagactaga gaaggatatg
     2041 aaaaacctgg tgttatatgt ttagtggaat actgtacaaa aaagaaagaa atagtaggat
     2101 atccaaagag aatatggtca gggggaactg atagaggttg tattgaagca ccacatataa
     2161 caaagcgtgg agattactat tatataatgt gtgcagaagg tggaactgga tatggtcata
     2221 gtgtaactat gggaagggct aaaaatatat ggggacctta tgaaaaagat tcaatgaatc
     2281 caattgtaac ttcaattcca ggcgattttt atgaaagaca tgaccctgac catctaaagc
     2341 ctaaatacta taacccagaa tcaaaacttc aaaaatctgg tcatggaagc tatatagaaa
     2401 caacatcagg tgaagtatat ttagttcatc taacatctag accatttgta ccagagttaa
     2461 ggtgtacttt aggtagagaa acagctattc aaaaaatgag atggacaaag gataattggc
     2521 ttcgaatgga agatgaaagt aatttggcaa aagaatacgt atcagaaagt aaactagaag
     2581 aacatttagt ttcatctata ccaagttttg atgactttga ttcaaatgaa ttaggtttac
     2641 agtactatgc tcctaggatt tcaccattat catttgcaga tgttaagtct agaccaggat
     2701 atgtaaggat tagaggacaa gaatcaagaa catcattaaa taaagtaagc atattggcaa
     2761 gaaaattaac ttcagtatat gcaagaataa ccactaagat ggagttttac ccagaggtac
     2821 atcagcatag tgcgggtttg ataatgtatt atgataatat gaattatata aatttaagaa
     2881 agtattatag tgaaacattg ggtcaaagtg cactatcaat aatacatctt gaaaatggag
     2941 agaagacgga atttttaaat actaggatac caataaaaga tataccaata tatcttcgtc
     3001 tgtatataca aggtcgtaag tcatattttg aatggagtta tgatgaaaaa aactaccaga
     3061 gaataggaaa ggtatttgat acaactaagt tttcagatga gtactgtaaa tatggagaat
     3121 ttacaggtac gtttataggg ttaacttgtg cagatcgtgt aaagcataaa cactatgctg
     3181 attttgattt ttttgaatat atagtagatg aatcaaaaga tgtcgattaa taaaatcatt
     3241 actaaaattt tcagagcaaa ggtaaatctt atgctctgaa ataagaaaca ttagaaggca
     3301 aatcttacaa aaaggagtat ggtattatga atacagaagt taatgttaaa gcaactacta
     3361 ttagatatga aaagatttca ttttttgaaa gaatttctta tggttgtggg gatttggggt
     3421 gcaatatcat atactcagct atgtcagcat ttttgctgtt ttattatact aattatgcag
     3481 atgttagtgc agcagctgta ggtagtatta tgcttgtatc taggatactg gatgggttta
     3541 gtgacttaac aatgggaatt atagtggata gaactaaatc caaatacggt aaggctaggc
     3601 cttggatttt gagaatggcg attccttttg ctatagcagc agtattatta ttttctgttc
     3661 catcaaatct tggtatcact tctaaattaa tttatatttt tattacatat aacttagttt
     3721 ctactgttat ttatacagca atcaatgtac cctatgcaac tctaaattca cttataactc
     3781 aaaaccagta tgaaagagga gtattaagta tatttagaat gatattagcc acttgtggta
     3841 ccttactaat aaatggactt acactacctc tagttgaata ctttggaaat aatttatcag
     3901 catgggctaa aacattcttt gtatttggaa tagcatctat aatggtattt tttataacat
     3961 ttactggaac caaggaaaga gtaaaagcag ttaagcaaga taggaatgaa gtaataccat
     4021 ttaaaatagg tattaaatct ttatttagaa ataagtactg gatacaaata acattatgtt
     4081 tagtttgcat atttattgta tttgcgataa atggtggttc atccgtatat tatgcaaagt
     4141 ttattttggg agatgaaaaa ttatttggtt ctataaatat ggtttcaaat atatcccaaa
     4201 ttatagctat gtttatggtt gctcctttta taaaaaaatt tggaaaaaga aatgtattaa
     4261 tagtaggttc aataatatta atatcgtcaa atgttatgtt tataatagtt ggacaagact
     4321 atataggagt aatattttca agtgctataa agggaatagg aagtgctgga atagcatcaa
     4381 caatgtttgc tattgtttca gatactattg aatatggaga atggaagact ggatatagaa
     4441 ctgaggggct tataaatagt gcatctagtt ttgggtttaa agtgggaaat ggattaggtt
     4501 cagcaatatt aggtgcagta ttatcaattg gtggttatgt aggaacatca gctactcaaa
     4561 gtgatttagc tatagtatca ataaaagtat gttttatata cctacctata tttataacaa
     4621 tattacaaat tatcataatg tctttttata agcttgataa agaatatagt actatactta
     4681 atgaattaaa tactaaataa tgaaaaagtt tcttataaag tcttaagttt aattaaggtc
     4741 tattgtaaat gttccctata aaaactatta tatatttatg attattgaag aatttttaga
     4801 gaagcgaata ataaaaatat aagaagactt taaatgatga aatggttggt tttttagaaa
     4861 tgatttaata agttattgtt atttaaagca ttataagtgg acaattaatt tttaatttat
     4921 ggagatgata tttaacaatt agaagtaata tataatatgc actaagaagc aatttttcaa
     4981 ctatttatga aggtggtggt acaagaaaag tatcaccttt tttttgttat acaaaaaaac
     5041 agttgacttt ttatatgaac cccttctata atgttactga aattaagtaa aatgattgaa
     5101 caaatgtaaa gataattgaa aagcttgatt ttggaggaaa gcaaatgaaa aaaattggag
     5161 acttaagatt aatgatgaag tgttgttcac tttattacga agataatttg aatcaacagg
     5221 aaatagcaaa tcaattggga atatcaagac caacaatatc aagaatatta aaagaagctt
     5281 ttgaacaagg aatagtaaaa atacagatag ttgatgtttt gaaaaatgat taccaaaaaa
     5341 tagagagaag tttggagaga aaatataaat taaaagaagt aatagtagta gatgataaac
     5401 aggatgcact aacacaaaaa caagaactag caagagctgt atctgaatat ttaactagag
     5461 tagtaaagga aaatgatata ataggtgttt caataggaac aacactaaaa gaaataccaa
     5521 gatatgtgga aaaaagtaac tgtaaaaatg ttacatttat acctctatta ggagggattg
     5581 gagacaatga aatagatatt catgcaaatc aaatagccgt aagtttagcg agggcttttg
     5641 gaggtgattt taaattatta catgctccag ctgttatgtc tgacttgtct acaaaagaga
     5701 aactttgcaa agacgaaaaa attaaagaag tgctagattt aatagataaa acaactatag
     5761 caattgtggg tataggaaat cctatgagtt taaactcaac aataatggct tctggataca
     5821 tgaatgaagc agatatagaa gatttaaaaa aatacaactc aataggtgca atttgtttac
     5881 aagcctttga taaagaagga aaaacttcta tacttgaatt taatcaaaga gtattaggag
     5941 tgaaactgga agatttaaaa aagataaaaa gaacaatagg tgtcgcttca ggagatgaaa
     6001 aaatagaggc aataaaggca tcattaaaag cgaaatttat aaatagttta gcaattaatc
     6061 acagtttagc acttaaatta ttagaagatt gtgactaata gaaagataga taaaagttaa
     6121 caggagggaa tgtatatgtc aatatcaaaa gaaacattgc ttgaaatgta taagagaatg
     6181 aatcaggcta gaaaatttga agagaaagtt agttggtttt ttgcaagagg tatggttcat
     6241 ggaacaactc acttatctgt aggtcaagaa gcgtcaagtg tggcggctgt aatggcttta
     6301 gaaaaaggag atttagtatc attaactcat agaggacata gtcaatttat aggaatggga
     6361 atagacctaa ataaaatgat ggctgaactt atgggtaaag aaactggatt ttgtaaggga
     6421 aaaggaggct caatgcatat agcagatatt gagtcaggta acttaggagc aaatggagtt
     6481 gtaggtggag gtcttacaat agctccagga gctgcactta cacaacagta taaaaaaaca
     6541 ggcaaaatag ttttatgtag ttttggtgat ggagcatcaa atgaaggtac ttttcatgaa
     6601 ggaataaatt tatcttcaat atggaaattg ccaataatat tttactgtga gaataattta
     6661 tacggtatgt caacaagcat aaaacgtcat atgaatatag aaagtattgc cactagagca
     6721 gcttcttatg gaatagaagg aatatcaata gatggatata acccaataga agtatacgaa
     6781 acagtacaaa aagctgctga gaagtgtaga agaggagaag gacctgtatt aattgaaagt
     6841 agaacttata gatggttagg tcattcaaaa tcagatgcaa atgtatatag aacaaaagaa
     6901 gaaatagaat catggaaagc aaaagaccct attgaatttt taaaaaatta tcttatagaa
     6961 aataatctat ctaatgaaga tgaattagat aagattcaag aatttgcaaa gcaatcaata
     7021 gaagatgcag tagagtttgc tcaaaatagc ccaaatccaa aaatagagtc tttattagag
     7081 gatgtatatg cagactaaga atggtaaagg aggaaaataa aaatgagtac aagggaatta
     7141 acatatgcac aagcaataaa ggaagcaatg tcagaagaaa tgagaagaga tgaaaatgta
     7201 atatttatgg gagaagatat aggaatatat ggaggagcat ttggtgtatc agttggtatg
     7261 atagatgaat ttggaccaga aagagtaagg gatactccta tatcagaagc agctatagca
     7321 ggagcggcag caggtgcagc agcaactggc ttaagaccta ttatggaagt aatgtttatg
     7381 gactttgtaa caatttctat ggatgcaatt gtaaatcaag cggcaaaaat gagatatatg
     7441 tttggaggaa aagcacaagt tccaatggtt gttagatgcc caggaggttc tggaactggt
     7501 tcagcagagc aacattcaca aagtttagaa gcttggtttt gtcatgtacc aggagtaaaa
     7561 gtagttgcac cttctacacc agcagatgct aagggattgt tgaaagcagc tataagagat
     7621 aataatccag tcatatttgt tgagaataaa ttgttataca gaaaaaaagg ttttgtgcca
     7681 gaagatgatt atgtaattga aattggaaag gcagatatta aaagagaggg tactgatgtt
     7741 acagtaatta cttatggaag aatgttacaa agtgttgaag aagcagcaga gactctatca
     7801 aaagaaaata taaatgttga aattatagat ttaagaactt tatatccatt agataaagag
     7861 actatagtaa agagtgtatg taaaactggg agagttttaa tttgccatga agcagctaag
     7921 actggtgggc taggtggaga aatatcagcc ctgataacag aaagtgaatc atttgattat
     7981 ttagatgctc cagtaaaaag aatttgtgga aaagatgtgc caataccata taatccagag
     8041 ttagaaaaag cagttgtccc aagagttgat gaaatagaag aagcaataaa atctttaatt
     8101 gttagataag gagggataga tatggtggca aataaaataa aagccacacc agcagctaga
     8161 agtcaggcaa gaaaagacaa tataaaatta gataggctga ttggaagtgg agaaaatgga
     8221 aggattcatt tagtagatgt gttaaattat ttaaaagata ataaagcaaa tactactcct
     8281 ttagctagaa gaatagcaga agatttaaat atagatttag aaactattgt aggtactgga
     8341 tataatggaa agataagaaa gtgtgatgtg gaaaaattaa ctggaaaaga aactattgta
     8401 tcaactaata catctaaatc tagtgagaaa aaagagctga aaattgaaaa tgaaaattca
     8461 agaatgttta acacagtaga aggaatattt gaaaagccaa atccaatgag agctactgta
     8521 gcaaaacgaa tgtcagaaag ttattttagt gctcctgtat ttacattcaa tatagaagta
     8581 gatgctacag aattgaaggt acttagagca aagttaatcg acacagtaaa agaatcaact
     8641 ggagtaaaat taactatgac agatttaata gtaatggcag tatctaaaat acttccaaat
     8701 catcaagcct taaattcagc atggacagat gagggtatat ttagatataa agatgtaaat
     8761 atagctattg cagttggttt agatgaaggc ttatatgttc cggtagtaaa aaatgcaaac
     8821 aaaaagtctt taaaagaaat agcaaaagaa agcaaagaac ttgcggaaaa agtaaagaca
     8881 gggaaactta tgccagcaga ccaagaaggt aatacattta caataagtaa tgttggaatg
     8941 tatggtataa ctacatttac acctataata aatatgcctt caagtgcaat cttaggggta
     9001 ggtgctacac aagataagtt tgttccagta aatggagagg ctaaaataaa acctataatg
     9061 aacttatcat taacatcaga ccatagagta atagatggaa cagtagctgc aaaattctta
     9121 aaagatttaa aagaattgtt ggaaaatcct ttatcaatgc ttgtataggt tttgatattt
     9181 tgttactgat ataaatagtt tgaatagatt atattattat aattgtttca gtaaatttaa
     9241 agcttttata tattaagaat tatttttaac agtaactata tgtgaatatg atttgcttaa
     9301 ttaaaatata agaaaataaa taggaggaga gcctatgtca gtagaagtaa taatgccaaa
     9361 agcaggagta gccatggaag aaggtactat agtatcttgg ctaaagcaag aaggcgaaga
     9421 agtaaagatt ggagaaccta tactagaaat aacaacagat aaagttaata tggagataga
     9481 gtcagaagga gaaggtacac ttgctgtaat catacataaa gaggaaggtg aagtattacc
     9541 agtatttaca gtaataggtg taatagcaga aaaaggggaa aatcaagagg aagtaaaagc
     9601 taaatattta tctggaaatg tttcaaaaga agatatagtt gaagagaatc aaaatataga
     9661 atttaaagaa gaaaaaataa acaaaaaaga gtgtaatcat gattatgatg tagtggtaat
     9721 aggaggagga cctgggggat atttatcagc attaaaagca gctcttttag gtggaagagt
     9781 tgctttagtt gaagaaaata tactaggagg tacttgctta aatagaggtt gtatccctac
     9841 aaagacttat ataaaaacag cagaaatatt agaagaaatt gaccaattat caaagagagg
     9901 tgtaaaagta actgtagata aagaacagga cattaagaag gccataaaat ataaaaatag
     9961 agtagttaaa aaacttacag ctggtgttgg cggattatta aaaagtagag atgtagatgt
    10021 gtttaatctt aaagctagtg ttaaagaaga gcataaagta attttatcag atggaaaagt
    10081 tttagataca gaaaatataa taattgctac aggttccaaa gtaaggatat tacctataaa
    10141 aggaatagaa tcaaatttaa taataactag tacagaagca ttagatttgg aaacagtgcc
    10201 agaagaatta gtaataattg gtggtggagt gattggttgt gaatttgcag agatattcaa
    10261 ttcaagaggt tctaaagtaa ctatagtaga aatggaagat agagtaatcc caagaatgga
    10321 taaagagtta agcgaatctt taaaatattc tcttagtaaa aaaggtataa atgtattaac
    10381 taaaaagaaa gtttctgaat ttaaagaaga aggaaataac atattagtgt gcattgaagg
    10441 tgaagagcca ataaaagcag atttatgtct atatgctata ggaagagaag ctaatctttc
    10501 tggcatagag gacttagata ttaaaataga taaaggttca atagttgtaa atagtaaaat
    10561 ggaaacaagt ataccaagca tatatgcagt aggtgatgtt actggaggtg taatgttagc
    10621 tcatgctgct tttaaaatgg gagaggtagc agcttcaaat gctctaggtg tgaataaaga
    10681 agttgactta ggtgcattac ctagttgtgt ttatacaatt ccagaagtag catcagttgg
    10741 tattacagaa gaggatgcta gaaaaaaata taatgtaaaa gttggtaagt ttaattttgc
    10801 tggaaatgga agagctttag cttctggtca agaacaagga tatgtgaagg tagtagcaga
    10861 tgctaaatat ggagaaattt taggtataca tatgtttgga tgtggtgtag cagaacttat
    10921 aaatcatgca gcatcattta aagcgttaga gatacctact gatgaagcaa gtgagttgat
    10981 atttggtcat ccatgtactt cagaagcttt aatggaagct ttggcagatg taaatggaga
    11041 atgtttacac ttacctaaaa aataaatcta aacataaatt attaatttaa gtctattatt
    11101 aatattaatt tatatcataa aattttaaaa cacttactta gccatacccc ttattatgca
    11161 aataatttat ttgcataata aggggtattt tttatggaaa aatatagaat atagaatcct
    11221 tgtagttttt gttgtacaaa aaagatagta atataaaata acattatcat tttagaatga
    11281 tttcaattgt aattaggaaa agtgattttt ttgtttttaa aaaaagtatt atttgtaaaa
    11341 tataaaaaaa aatttcttaa tatttgaata aaagaatagc ttaatttaaa tgttattact
    11401 ttataaaaaa ataataagta caaaaaaaac aatatatggc atataagttg ctatataaat
    11461 aataaggagg gaacaattat aaatgaggca aagaataaaa aacttaattg aaaatgaaga
    11521 taagaaaaat cctttaacag atgaagcgat ttcaagtagg ttaaatattc gaagagaaga
    11581 tgttaccttt ttgagaaatg agttaaaaat agaagattca agacaaagaa gaaaagttgt
    11641 tttaattaaa gctataaaag atattttaaa agaagaaaaa actataaata aaaatgatat
    11701 aacaagaaga ttaaacagca ttgggtttac agtatcaaga tttacagtca tacaatactt
    11761 aaaagagatt caagattctg gtgacctaaa acttgataaa gagagtgatg ataaaaaaga
    11821 agaaataatc aataatagag aaaataaaga tatagcattt gataaactca taggtagtag
    11881 tggtagctta agtacaatta taaaactagc caaagcagca attctttatc cacctcatgg
    11941 tcttcatact attattatgg ggccaactgg tgttggaaag agtgagttag cagagtgtat
    12001 gtataaattt gcagtagaat catccagatt ccctaagaat gcaccattta tagtttttaa
    12061 tgcagcagat tattcagaga atccacagct tttgctatca cagttatttg gacacgttaa
    12121 aggtgctttt acaggagctg atgagaacaa agaaggatta gtatcaaagg cagatggagg
    12181 aatattgttt atagatgaaa tacatagatt acctcatgaa ggtcaagaaa tactatttca
    12241 actgattgat aaaggtatgg tcagaaagtt aggagaaaca agactaacac ataaaataga
    12301 tgtaatgatt atttcagcaa cttctgagcc aatagattct catttactta atacatttaa
    12361 aagacgtata cctgtaacaa ttgaaatacc agaattagtt gcaagaccat taaatgagag
    12421 gtttgacatt ataaataatt tcttcttaat agaagctcaa agaatgggag caaacataca
    12481 tataaagtca gatgtattaa aagctcttat gctttacgat tgtataggta atgtaggtca
    12541 acttagaagt gatattcaag tagcttgtgc taggggacta ttaaaccaac ttacaaacaa
    12601 actaaaagaa gtaaatataa gcatatcaga tgtacctgga tatgtaaaac aaggtcttat
    12661 aaaaatcaga aattgtagag ggaaaataga aaattatgta gatggggatt taattataga
    12721 ctcaaatctt caaggtgaga tagaaaagaa aaatgaagat atatatactt ttccagatga
    12781 aatatacaaa cttactgaaa gaagacatat tgatttattg gaacaaggtt tagattttga
    12841 tgttataaat agaatcattg gaggagaatt agaaagttgc attcaaaaat acataaaaca
    12901 agttaaaaaa gtttctatta gtaacaatct tccagatata agtccaattg ttggaaaata
    12961 tatcgtagag ctaacttatg aagtaatcaa aatagcatca caatacctca gttcactaga
    13021 accgaatcta catttatgtt tagcagttca cctaaaagca gcttttgaga gattaaaaga
    13081 aggaaaagta atatcaaatg ctcatttgaa agaaataata ggaaattatc cagtagaata
    13141 ttctgtagca gaaaaggtag ctcaatattt aaaggaaaga tataacataa acttaccaaa
    13201 agaagaaata ggtataatag caatatattt taaaatgagt agtagaagag atatgtctga
    13261 acaaaaaaag ataggcgtac ttcttatggc tcacggaaga gtagcatctt ctgtatgtga
    13321 ggttacaaat aaactattag gaattaatca cgcaaggtat ttagatatgc catttgagaa
    13381 gaagccggaa gaaatgattg aagaagctac tacaataata aaagatattg atgaaggtag
    13441 aggtgtgatt atattagtag atatgggttc actttcatat tttggagata ttatttctgg
    13501 aaagactgga attaatataa ggacaatatc tagatttgat acattgcttt ctatagaggt
    13561 tatacgaaga gcagttttac cagatttaac aatagacgag atagttgatg aagttaaagg
    13621 tatagagcca caagtaaaag aaaaggttag taaatgtaac aatacaaaag tagattttag
    13681 aaaacctata attttaacat tatgtattac tggattaggg ggagcttgta agataaaaaa
    13741 aatcttagag gaaaatatta aaagtataac tgaaaaggtt gatatagaac ctataggtat
    13801 gattgaatat ccaagtcttg atttagagat aaaacaaata agcaatgata aaaatgtaat
    13861 cgccatagtt ggaacaattg accctcagat agcaaatatc ccttttttta gtctagtaga
    13921 cataaatgat aaagcaaagt taaatcaaat aaataaccta attgatacaa atcaaattgg
    13981 tgaaacaaat aaaaaatatg aattatcaga tttaatacat aaagaagata tatttgtgga
    14041 tttacaggtt aaatcaaaag aagaagttct aaaatatatg agtaaaaaac ttagagagaa
    14101 aggttatgtg acaaaaaatt tctataaaaa agtagtggaa agagataact tatttccaac
    14161 tgaattatca gatgaaatag caatacctca cacagatgga atagatgtaa ttaggccagc
    14221 tataagtata gccatcttaa agaagcctat tgtgtggagt aaaagtaaag taaaaataat
    14281 acttttatta gctgtagacc aaaagtgttt taatccatta agcactctac tctcatttat
    14341 agaaacagat gaatttaaga agataaaaaa cattaaagat agagatttta ttagggagat
    14401 gatattagat ggagtcaatg aaaataatta gtagcaattt aatttttaaa aatattgaag
    14461 tgtctaacaa tgaagatgca ttaaagtttt tgggacaacg tttgtttgac gaacagtatg
    14521 taaaagaaag ctacatacaa gctgttgtag caagagaaaa aaagtatgct acagggttac
    14581 caacagaaat atacggagtg gcaataccac atacagatat agtacatgta aatgagccag
    14641 gaatagcaat tggaatactg aataaacctg taaaatttat aatgatgggt acagacgata
    14701 ctgaaattga tgtaaaagtt gtatttatgt tagcagtgaa agagccacaa gaacaattgc
    14761 aactattaga aaaacttatg actatatttc aagataagaa tatactaaat aatattgttg
    14821 acttaagtga agaaagtgtg agtgatttat taaactctaa attgaaaaat taaacatgta
    14881 aagtatatta aaaatgtaaa aagattatta aagatttcta actatagata tctttaaaat
    14941 aaaataattt caatgggggt gactaatgtg gctaaaaaga tattagttgc atgtggaaca
    15001 ggagtatgta cttcaacaat tgctataaac aaattaaaga aagcacttca agacattggt
    15061 aaattggata tggttaatat tacacaatgt aaagtagtag aagttgcatc aaaagcacct
    15121 gattatgatt taataatttg tactacacaa gtatctagta gtataaaaac accagtgata
    15181 aatggcttac cttttttaac tggtgtcgga atggataaat taatcaatga tgtattagaa
    15241 gagttagaat tataattaaa aaaattaagg aacatggtct ctaaaatcat aagttttaga
    15301 gacttaaaat taaataatgg agggtcttta tatggagata ttaaatttca ttgttggtct
    15361 aggtgcacaa gtaatgatgc caataataat atgtattttt ggtttgatat taggtacaaa
    15421 actaggaaaa tctttaagag ctggtttaac tgtgggagtt gggtttatag gtcttaacac
    15481 tattatagct ttgctaacag ataatttagg tccagctaca caacaaatgg ttaagaattt
    15541 agggctaagt ttatcaataa tagatgtagg atggccagca gcatcagcta tagcttttgc
    15601 atcaacagta ggggctttaa ttattccaat aggtcttgtg gtaaatatag ttatgctaat
    15661 tactaatact actcaaactg ttgatgtaga catatgggat tactggcatt ttgcttttac
    15721 aggagcttta gtggcagggg ctactcaaag tgtaatgtgg ggagtatttg cagcagtagc
    15781 aaatatggta attgtattgg taatggcaga tttaactgct ccaggtatag aggaatattt
    15841 aggtatgcca ggtatatctc ttcctcatgg atttacacag gcatttgttc caattgctat
    15901 agtagtaaat aaattattag acctaatacc aggcataaat aagattgaga taaatgctga
    15961 tacattgcag aaaaaatttg gattatttgg agaaccttta ataatggggt ctgtaatagg
    16021 tgtaataatt ggtattgctg cgaaatatga tataaaagga atattacaat taggtgtaac
    16081 tatgggagct gtattaatat taattccaaa gatggcagca ttattaatgg aaggattatt
    16141 accagtatca gaagctgcac aggaatttat tgagaagaga tttaaaaaca gaggcaagat
    16201 ttatataggc ttagattcag cagtaggaat aggtcatcct gttacattat cagttgcact
    16261 agtgttggtt cctttgacta tacttatagc agctatattg ccaggaaata aagttttacc
    16321 atttgcagat ttagcagtaa ttccatttgc acttgtatta atcgtaccaa ttacaaaggg
    16381 aaatgtgttt agaacattaa taataggaat aattataatt acttctggat tattaatcgc
    16441 aactaactta gctccattat ttacccaaat ggctttaaat gctagtttta aaatgcctga
    16501 aggagcaact atgatttcaa gtatttgtga tggtgcgaat ccattaagtt gggtatttgt
    16561 aaaagttatg aactataaag ttattggagg agtagttttt ggagttatag ctttaggaat
    16621 ggctatttac aataggaata gaataataaa tgaaaataaa aagctatcta tagaagaata
    16681 aggctaaaac aattttatta aggagtgtat aggttatgaa aaaatataaa tatgattcta
    16741 aaagatactt actcagtgtt acaataccag gattttttat gattttaata ttgatttatg
    16801 cactgtttaa taactataca aattttaatt tgaatatata tagtttgtta ataattgtct
    16861 gtacttatgg tatattcaat acttttatat catcaagtaa tcctaaaaaa attattattg
    16921 atagcaaatg tatacatttt acctcattta tgactacaca taagtatgaa attaaagata
    16981 tagaaaagat aagaataaga gaattttata ataaaaaaat ttatgtaaaa attaatgatg
    17041 gaaacctttt taaaggtagg tattggataa gaacaaatat gtttaataat agtatagcat
    17101 tatatagcta tttcattgag ttggaagagt gcttatatcc agattcacta aaatttagaa
    17161 ataaaaaatt tgagaataag aacatataaa aataaaaaat tgaattgaag cctagcttaa
    17221 tcttttttga taagatataa gtttgaactt tatactaaat ttttagaatt ttcaatcaag
    17281 acaataacat aatagctaag caattagaac acaattaaga tgtataaggc atgtatatga
    17341 tgaatgggag gatttaatta atgttattag agaaattaag aaaagaagta ttacaagcat
    17401 ctttagacct tttaaactat aatttagtga cattaacagg aggaaatgta agtgggagag
    17461 atgaacaaac tggctatata gcaatcaccc caagtggaat ggattataga aatcttacac
    17521 caagtgatat tgttatagta gatgtagatg gaaatattat agatggaaaa tggaaagcat
    17581 cagtggattt atcagaccac ttgtatatat ataagcatag agaaggcata aatagtataa
    17641 ttcatacaca ttctacatac tcaagttgtt ttgctatttt aaatgaacct atagaatgtg
    17701 caagtacaac tcttgcaaat gaagtagggg gttcagtacc agttgcaaaa ttttcaccac
    17761 caacatctaa aaagatggga aaatgtgtta ttgaagcaat tggtgacaaa agagcatgtc
    17821 ttttagcaaa tcatggcgta attgcagttg gtccatctgt aggacatgct cttacagccg
    17881 ctgtaatgtt agaagattca gcaaaagtat attacttagc aaaatcaatt ggcacaccag
    17941 tgctactgcc tgatgaagaa attcaaagag cgagagatgt attttttaat gtctatggtc
    18001 aggataaata aattagataa aattttaaaa gtaatatgaa aatatagata ttcaatgata
    18061 ttaaggagat ttataatgat ataataagtt taatagttaa gaagtaaaat atgaaatgta
    18121 atagtatata aattcattta agactaaaaa gaataagata aaataaaaag gagtctgtat
    18181 ttctatgtat tacttattaa acaaaagcac aaatccttac tttaatttgg cattagaaga
    18241 atatctattt ttaaatgata aatataatga tgatattata atcatatgga gaaatgaaga
    18301 atccattttt ataggtaaaa atcaaaatcc atatcaggaa gtatattatg atgttattga
    18361 aaagggagaa attcctattt taagaagaat atctggagga ggaactgttt atcatgactt
    18421 aggtaatatc aatatgtcat tcatacaaaa aaataggcaa cttcatgaga tagatttttt
    18481 ggagcacact aagtttatgc aaaagatgct ttcaacctta ggactagatg tatctataac
    18541 tgaaagaaaa gatttatttt taaatgggaa aaaaatttca ggttctgcac agtctataaa
    18601 aagaaaaaat tctctttatc atggaactct tctttacgat tcagatttaa ataaattaac
    18661 taaatattta aattcaaata aagcaactga atcaaatgca actaaatctg tttcaagtaa
    18721 agttacaaat attaagtttt tactcgaaaa agatataaat tactttttag attattgtgt
    18781 tgaatattta aaatctaata taaagaatat aaaagaactt gaattggatg aagaagatat
    18841 taaaagtgta tacaatatag gagaagataa atataaaaag atagagtgga catatggtaa
    18901 aacgccgaaa tttcaagtag tgctaccatt taataatgaa agtaaaataa atatacatgt
    18961 taacagatgg aaagtatcaa aattttttat ttcttatgat gataatgtaa ttaatatgga
    19021 caagttgtta gatttgaatt tctttaaaga agaaataaaa gagagtattt tagaaaatta
    19081 tccacattac atagatttaa tcaatttaat attttaatat aaaacctcta atttgataaa
    19141 attgtcttat atcaaactag aggtttttaa tattcttgca tattaacaac cattacaaaa
    19201 ttgtaaaatt aaaaacaaca ctattgaaaa atcaatatat attgtaataa atatatgtgt
    19261 ttttcattag caaatagaca ttaactattt atacaactga aaatttaata tataattaat
    19321 cagatggtta aaataaaaat attaaaagtt ttaataaatg atggttaaaa ataaaatacg
    19381 aggtgatacc atgtatagtg ttataattgt tgcagcggga agcggaagga gaatgaactt
    19441 agatataaac aaacagttca taaaattaag agaaaaagaa attattgctc atacaattca
    19501 agttttttat gaaaatataa atatagatga aatagtggta tgtataaaaa aagaagaaga
    19561 agattttttt aaagaaaata taataaataa gtataacttt aaaaatataa aaatagcata
    19621 tggcggaaaa gaaagacagg actcaatata taatggttta aaaaaattag atgaaaattg
    19681 tgatatagta cttatccatg atggagcaag accatttgtc gaccatagaa taatcaatga
    19741 atctataaag gtagctaaag aaaaaaaggc tgtggttgta ggtgttccag taagtgatac
    19801 tataaagata gtgtcagatg gaacagtaca agaaactcca gaaagaaatt tgctgtgggc
    19861 agcacaaacc cctcaaacct ttgaatataa tctcataata gatgcttatg aacaagcata
    19921 taagaacaat tattatggta ctgatgattc aatgttggta gaaaatatag gtcaaagtgt
    19981 cactatggta atgggttctt atgaaaacat aaaaataact agtccagaag atttaaatat
    20041 agcagaacaa atattaaata tggaaaaaag agatgaagtt aacagtagaa ggagaattat
    20101 atgagaatag gattaggata tgatgtacac aaattaacag aggatagaaa acttataatc
    20161 ggtggtgtag agataccaca cgataaaggt ttgttgggtc attctgatgc tgatgtattg
    20221 atacatgcaa taatggattc tattttaggt gctctagcat taggagatat agggaagcat
    20281 ttcccagata cagatgaaga atataaggga gcagatagta tgaaattatt agaacatgtg
    20341 tataatctaa taacaagtaa aggatataaa attggtaata tagacagtac tataattgct
    20401 caaagcccta agatggctcc atatattgag agtatgagaa gtaatatatc aaaagtttta
    20461 aacacagaca ttgataatat aaacataaag gcaacaacag aagaaggtct tggttttaca
    20521 ggagcaaaac agggaatagc ttcacaaagt atttgtttat tattgttgac aagtcagaat
    20581 aattaatata ttattagtaa taagtttaat ggatatcaag taataggcct atatagaata
    20641 tctataatgt atgaatttaa gtgaaattaa tataaatata aaattagcta tgataaagaa
    20701 atagtaaaat gatgaaatct tcacagagag aaaacggtgg tgagagtttt caagaggaag
    20761 tctttgaacc tgtcttttag cttaaaggta taaaaatctt tacggtagga accgttatat
    20821 tcccaaaaga gagctattca tatagctaac tagagtggta ccgcggaaat taaacctttc
    20881 gtctctatac ttgtatagag atgagaggtt ttttatattt tcaggaagtt aatattcagg
    20941 aggaatctat taatgaaaat gtcaaaaatg tttatgccga cattaaaaga aatcccagca
    21001 gatgctgaga ttacaagcca tcaattaatg gttaggtcag gcatgataaa aaaaatgact
    21061 tcaggtgttt ataaccaatt accaatgggg ttaagagtgt tcaaaaaaat tgaacaaata
    21121 attagagaag aattaaataa aaaagattgt caagaaatac tttgtgcagc cttacttcct
    21181 tctgaattat ggaaagagtc tggaaggtgg actgctatgg gtgaagaaat gtttagacta
    21241 aaagacagaa cagaaagaga gtactgtctt gggccaacac atgaagaagc attcactgat
    21301 ataataagac aagaaattac ttcatataaa caattgccac taaacttgta ccaaatacaa
    21361 gtaaaatata gagacgagag aagaccaaga tttggtgtta tgagaactaa gacttttaca
    21421 atgaaggatg cctatagttt tgatgtagat gataaaggtt tagataagtc atatcaagat
    21481 atgtttgatg catatgtaag tatatttgat agatgtggat tggagaatag ccctgtacag
    21541 gcagattcag gagctatagg aggttctaca tcagccgaat ttatggttaa gtcagaagtt
    21601 ggtgaagatg aagttgtatt ttgtagtgga tgtgattatg cagccaatgt agaaagagca
    21661 gaatcttgta atctagcatc acaaaaagaa gaaatgaaag aattagaaga ggttcataca
    21721 ccaggagcag ctacaataaa agagttagaa gaatttttaa aaacttctcc agataagttt
    21781 gctaaaactt tagtatatga ggcagatgga aaaacagttg tagtcgttgt aagaggagat
    21841 agagaagtta atgaaatcaa agtatctaat gccataggtt ctgttataga atttgctctt
    21901 gctacagatg atgtagtgag aaaagtaact aatgcagaag taggatttgc aggtccaata
    21961 ggtataaatg ctgactatgt atttatagat aaagaaattg ttgaacaaag aaacatagtt
    22021 gttggggcta ataaaactga gtaccatata aaaaatgcta actatggaag agattttgaa
    22081 ggaatagttg gagattttag aaatgttcaa gaaggcgaca agtgtatagt atgtggtaag
    22141 ccacttgaaa tagctagagg tgttgaagta ggacatatat ttaaactagg aactaagtac
    22201 tcagaatcta tgaatgcaaa cttcatagac aaagatggaa aatcaaagcc tatagtaatg
    22261 ggatgttatg gaataggtgt tgaaagaaca gcagcagcta taattgaaca acataatgat
    22321 gagaaaggta taatatggcc tttgtcagta gctccatacc atgttgtgat agttccagca
    22381 aatatgaaaa atgaagaaca aatatcaata gctgaaaata tatataatga tttgcaagct
    22441 atgggtgtag aagttttatt agatgacaga gatgaaagaa taggtgtcaa attcaatgat
    22501 tcagaattaa taggaatacc tatgaggatt acagtaggta aaaatattaa tgaaggtaaa
    22561 gtagaattta aacttagaca taaagaagat aaagagataa ttgacataga agaaataaat
    22621 gaaaaagtaa aggcagagtt tatcaggaat aatgttaggt taggataata acttaaataa
    22681 gatattgtat agataatcaa agttgtactt tatagacacc attttatcta tatataagga
    22741 tataaaatgg tgttttttta taaaacaaat aaatgaggag gtaattgaaa tggcaaaaaa
    22801 tgaaaaacaa tttgttgaag aaataacaaa gatggaagat gattttccac aatggtacac
    22861 agatgtaata actaagactg acttagttga ttatgcacca gtaaaaggtt ttatggttgt
    22921 aaagccatat ggatatgcat tatgggaaaa gatgcaagaa tttatggata aaaaatttaa
    22981 agaaactgga cataaaaact gttattttcc attattaata ccagagagtt tattaaacaa
    23041 agaagcagaa cacgttgaag gttttgctcc agaagttgca tgggtaacac atggaggaaa
    23101 taaaaaatta gaagaaagat tatgtgtaag acctacttca gagactataa tatgtacaat
    23161 gtatgcgaaa tggttaaaat catatagaga attaccatat ctttataatc aatggtgctc
    23221 agttgttaga tgggaaaaat caactagacc tttcttaaga acatctgagt ttttatggca
    23281 agaaggtcat acattacatg aaacagcaga agaagcacaa gaagaaacaa tacaacaatt
    23341 agaagtatat aaagcgctat gtgaagaatt acttgcaatg ccagttgtag ctggtcaaaa
    23401 aagtgaaagt gagaaatttg caggtggtga aagaacatat actatagaag ctatgatgca
    23461 tgatggtaaa gcattacaat caggtacaag tcacttccta ggtcaacact ttactaaggc
    23521 ttttgatatt acttttgcag atagggaagg aaatttagct aatccatacc atacatcttg
    23581 gggagcatct acaagactta taggtggact tataatgact catagtgata acagaggttt
    23641 agtattacca ccaagagtag ctccaattca agttgttata gttcctatag ctgctaaaaa
    23701 aggaaatgta atggagactg ttgataaaat atatgctgat ttaaaagcta agggagtagc
    23761 tgtagaagtt gatgatagag ataactatac aactggatgg aaatttaatg agtgggaaat
    23821 gaaaggtgtt ccagtaagag ttgaaattgg accaaaagat atagaaaata atcaagctat
    23881 ggtatttaga agagatactt tagaaaagga ttctatgcct ttagaaggat tagctgatgc
    23941 tatatgtgat ttatttgatg ttatacacaa tgatatgttt gaaaaagcaa gaaaacatag
    24001 agaagacaat acatctatag ttgaaaatat ggatgagttt agaaaagctt tagaagaaaa
    24061 gccaggattc ataaagacta tgtggtgtgg agatgcagaa tgtgaagcta agattaagga
    24121 agaaacagga gcaactataa gatgcttacc ttttgaacaa gaaaacttag gtcacaagtg
    24181 tgtgtactgt ggaaaagaag cagatagtat ggtagtaatg gcaaaagctt actaaaatac
    24241 atttaaataa aaactggggt agaaagtatt taatacttta tcccagtttt ttgtttttta
    24301 tgagtaataa aatgtatttg taactatgtc ataagataag tcatagatac ttatattaaa
    24361 aagaatataa tagagaacta tttttaataa ttacatatta atgaaagcaa aatattttgt
    24421 tatatagatt ttcaataaag caaacaataa atataaatga atattaataa ggagtgcttt
    24481 taatttttag aaaataaatg acttaaaaga aagatttatg aaattaaaac taggattttc
    24541 tgatataata aacatgtgta tttttaaata aaaaggatat tattattaga tttgattaaa
    24601 aataaacttg caaaacaatg tactagttta atattatagt tatattgaat aaaatatcag
    24661 gaggaagtaa aaatgaatgt aagagtaagg tttgcaccaa gtccaacagg atttgtacat
    24721 ataggtagtt tgagaactgc tttatataac tatttatttg caaaaaaaat gggcggagaa
    24781 tatatattaa gagtggaaga tacagaccaa agtagattag tagaaggtgc tatagagaat
    24841 atgcttaatg ctatgaaatg ggctggggtc aaccatagtg aaggtgttat attagatgat
    24901 agtggaaaag tagtacaaaa aggagaatat ggtccatata ttcaatctca aagattagat
    24961 atataccaag aatatataaa gcaactttta gatagtggaa aagcttatta ctgtttctgt
    25021 acaaaagaaa gactggatga agtaagagat gctcaaagag cagcaggaga aacagctaaa
    25081 tatgatggtc attgtaagaa tctttctaaa gaagaagtag aagcgaatat aaaagcagga
    25141 ataccatatg ttataagatt aagattgcca gagaatcata caattaagtt tacagactta
    25201 gttagaggag atatggaatt taatactaat gacttagatg accaagtatt aatgaaaaca
    25261 gatggatttc caacttatca ttttgcagta gttgttgatg actatttgat gaaaattaca
    25321 catgttataa gaggagaaga atgggtatca tctactccaa aacatgttta tttatatgaa
    25381 gcttttggat gggaagcacc tgtatttgtg catttaccaa atatacttaa taaagaaaag
    25441 aaaaaattaa gtaaaagaca aggtgatgta gctgttgaag actttaagaa aaaaggatat
    25501 ttaccagagg gattagtaaa ctatgtagca ttagttggtt ggtctcctga agataatcaa
    25561 gaattgttta caatggagga attagaaaaa gccttctctg tagaaagagt ctctaaaagt
    25621 ggtggagtat ttgatactga aaaattaaat tgggttaatc agcattatat aaaagatggt
    25681 gatgatgctt atctaacaga cttagcaata ccatttttaa tagaagatgg atttataaca
    25741 gaagaagaag ctactaataa atatgatttc ttaaagagta tgatatcagt acttaaagag
    25801 aaattacaat atgtaaaaga agttactgaa catgcaagta tattttttgg agataaaata
    25861 gaggtagaaa ctgaagaggg aagagagttc ttaagattag aacatatacc tactttaata
    25921 gatgctttga gagaaaaaat agaaaaaaca gaggtattaa atgctgagtt tgttcaagct
    25981 atgcttaaag aaatacaaaa agagtacaaa ataaaaggga aaaatttatt tatgggctca
    26041 agaataattt tgacagggca aatgcatggt ccagatttac caaaagtaat ggaagtttta
    26101 ggaaaagaaa cttgcttaaa tagaatagct tatgtaaaaa ataatatatt atagtcataa
    26161 aagtccgcta atttagaagc ggactttttt tgtgttagta tttggtgaaa atatctgctt
    26221 aagaaaatga aggtatttaa ggtaataaat ttaatatata aaaagcaaag caaaaatata
    26281 aataaaatat gaataataaa ctaataaaat attaagcata gaagaaggga atctattatt
    26341 ttagtttgat ttaattatta agggggtaat tactatgtat agtaatattg atgatgttaa
    26401 aaaggaatta aaggagctat gcttagaata tgttacaatt ttagaaaaat taaaagatga
    26461 aaaaatgatt acagaagaaa cttttgaaaa gtgctcttct caaaaaaaaa tatttttaga
    26521 agaacaatag aggatggtaa tagtattatt attatgtagt ttgaaagata gtacgaaaaa
    26581 tgatagtaat actattattt attgcaattt tcaactataa tataatatat aatgttaaga
    26641 agataattta taaaaataca gtgaggtgat gagtgtgaaa gtttataata cattgactag
    26701 aacaaaagaa gaatttgttc cattagaaga aggaaaggta aaaatgtatg tgtgtggtcc
    26761 aacagtttat aactatatac acataggtaa tgcaagacca tttataatat ttgatactct
    26821 aagaaggtat ttagagtata gaggatatga tgtaacttat gtacaaaact ttacagatgt
    26881 tgatgataag attataaata gaagtcatga ggagggaata tctcctgaag aagttgcggc
    26941 taagtatata aaagaatatt ttgtagactg tgatgggcta ggaataaaaa gagctactgt
    27001 tcatcctcag gttacagata atatacaaca gattatagag tttataaaag agttggaaga
    27061 taagggatat gcatatgcag taaatggtga tgtatatttt gatacaaata agtttgaagg
    27121 ttatggaaaa ctttcaggtc aaaaacaaga agatttagag gcaggggcta gaattgaggt
    27181 taatgaccaa aaaagacatc ctatggactt tgttctttgg aaggcaaaaa aagaaggtga
    27241 gccaggatgg gatagccctt ggggagaagg tagaccagga tggcatatag aatgttctgt
    27301 tatgtctaag agatatttag gtgaaacaat tgatatacat gcaggtgggc aagatttaac
    27361 attcccacat catgaaaatg aaatagctca aagtgaagct agaagtggaa aaacattctc
    27421 aaaatactgg atgcataatg gatatataaa tataaatgat gaaaagatga gtaaatcaaa
    27481 aggtaatttc tttacagtaa gagatatatc aaaattatat gatttagaga tagtaagatt
    27541 tttcatgtta tcagcacatt atagaaatcc agtaaacttt agtgatgaga tgttaaatca
    27601 agctaaagca ggtcttgaaa gactatataa tactaaagaa aaattagaat ttacgctaag
    27661 taatttagta gaatctcctt taacagaaaa agaagtagag cttgttaaag aattagatga
    27721 ctttagacaa aaattcatag atgctatgga tgatgatgtt aatacagcag acgcagtaag
    27781 tgtaatattt gaattagcta agttaataaa ttctaatgta gatgaaaatt cttctttgga
    27841 gtttgctaaa aaatgcttag atgaatttaa tgaacttaca ggagtattaa atattgtaaa
    27901 taagaaaaag gatactgtat tagataaaga cattgaagaa ttgatacaaa aaagaactga
    27961 tgcaaagaaa aataaagagt ttcaattagc tgatgatatt agacaacaat tactaggtat
    28021 gggaattgta ttagaagaca caagacaagg tgttaagtgg aaaaggatat aaaaatggaa
    28081 aaaactgaat tagttactat gtcaccatta gttttagcat acttaggtga tacagtgtat
    28141 gagacatata taagagaata tttaattaga cagaatacac aaagaaaagt taatgatttg
    28201 cataaactag ctataaagta tgtaaaagct aaagctcagg caactataat tcatgaaatt
    28261 gaaattgagt taactgaaga agagagtaaa atttataaaa ggggaagaaa tcaaaagtca
    28321 aatacttctc ctaagaatgc agatattata gactacaaac atgcaactgg gtttgaggca
    28381 ttagtgggat atttgtattt aaataatgaa atagagagac tacaatatat tatcaataaa
    28441 ggaatcaaaa ttattgaaag agatatgtaa atattaaaga gtgttgtctt aataataagt
    28501 aataaggcaa cacttttttt ataactaatg tataataaat atatagaaat tagtaatgag
    28561 aaaggataaa aagttatgaa agtaaaatta atatcacata cacctgaacc agaaaaagta
    28621 atagctatgg cagctaagct atgttattca ccagttggga cagacgaaat agaaaaagac
    28681 ttaacagatg aaagtataga gaaattttta aatatgttat taagtatagg tcatgggtca
    28741 atattagaac atgcttcatt tacattttca atagaaggta tttcaagggc ttgttcacat
    28801 caaattgtta gacatcgtat agctagtttt tcacaacaaa gtcaaagata tgttaaatta
    28861 gaacaatttg agtacataat tcctccagaa atagaaaaaa tagaaaaagc aaaagagtta
    28921 tttatagact ccatgaaaaa agaccaagag aattatgata agttagttga aatattgttt
    28981 gaaaatcatt ataatgacct aataaaaaac ggtaaaaatg agaaaacagc taaaagacaa
    29041 gctgaaaaga aagcaataga agatgctaga tacgtatttc caaatgcatg tgaaacaaaa
    29101 atggtattta ctataaatgc tagaagtttg tttaatttct ttgaacatag atgctgtgaa
    29161 agagcacagt gggaaataag aaatttggct gtggagatgt taaaagaggt taaaaaggtt
    29221 gctcctatat tatttaaaaa aactggtcca agttgtgtaa atggaagttg tccagaagga
    29281 actatgactt gtggagatat agttcaagtt agagaaaaat ttaaggcctt gtaggaggtg
    29341 aataatttgg cgagtataga aggaagaaat ccggtaatag aagcaataaa aagcgacaga
    29401 gaaatagata aaatattaat tgcaaattca gctaaagaag gttcaattaa gaaaataata
    29461 ggaatggcta aagataagaa tataattatt cagtatgttg ataaacataa gctagatgaa
    29521 gtaagtacaa gtcattcaca tcaaggtgta atagcttatg caagtgagta taagtattat
    29581 gaattagatg agctaataga tttagcaaag aataaagatg aagacccatt tttcattata
    29641 ttagatgaga taacagaccc acataatttg ggttcaataa taaggacagc agatgcagta
    29701 ggagcacatg gagttatcat tccaaaaaga aggtctgtac acataactcc tgtagttgcc
    29761 aaagcatctg ctggagcagt agaatatatg ccagtttgca aggtaaccaa tatagttaat
    29821 acaataaaaa gactcaaaga agaagggctg tggattgctg cagctgatat ggatggagaa
    29881 actttttata aacaaaatct tactggtcct cttggtgtag taattggaag tgaaggtttt
    29941 ggaatatcta gattggttaa acaaaactgt gactttatag taaaaatgcc aatgataggt
    30001 aatgttacat ctttaaatgc atctgtagca ggtggaatac ttttatatga gatattcaga
    30061 caaagactgg ataaaagtaa ataggcatga aaaaaaatat aaatcattac ttaataatag
    30121 atggctacaa tattataaat gcgtgggaca atttgaaaga actggctaaa gaggacttag
    30181 aagattctcg agaaaagctt attgatgaca ttatagaatt ttctgagttt atgggttata
    30241 agactataat agtttttgat gcttataatg ttaaaaattc tcgagaaaaa gttgaaaaaa
    30301 gaaaacacat aacaatagtt tatacaagag aacaccaaac agcagatagt tatatagaga
    30361 aatttataac ttctttatca aagtatgatg atgtaaaagt agccactaat gactatgcag
    30421 aacagcaaat gattttagga aaaggtgcta ctagaatgtc tgcaagagaa ttaaagttag
    30481 agttagatcg ttccaagaat aaaatgaagg aaaaaaatat cggtttgagg aaaaaaattc
    30541 agcgaaattg gttggaggaa aggttagata aagaaacatt gtcgaaactt gagaacattc
    30601 gtagaaagcg ttgaaattac taggttcttt agactataat atacctataa atttgtttta
    30661 tatatggggg agatttacat gttggtagca aaagaaaaaa gttatgagtt agtggacaat
    30721 tgtcagcagg atgagtataa cattgtatta agagcaagtg aaggggataa aatagcacta
    30781 gagtacatta ttactaaata cagaaatttt gtaaaggcaa aagcaaagtc atatttttta
    30841 attggagcag ataaagaaga tataatacaa gaaggaatga taggccttta taaggcagtt
    30901 agagattttg atggaagtaa gaccaattca tttaaatgtt ttgcggagat atgtataaca
    30961 agacaaataa taactgctat aaaaactgca acaagacaaa aacatatacc tttaaattca
    31021 tatgtttctt tgaataaacc aatatatgat gaagagtcag acagaacact tttagatatt
    31081 atagctacaa gtatagtaac agatccagaa gagcttataa ttagtaaaga agagttaaaa
    31141 aatatagaat caaaaatgaa cgaattgtta agtgacttgg aattagaagt actagaatta
    31201 tatttaaatg gaaagtcata ccagtttata gcggacaagc ttaaaagaga tgtaaagtca
    31261 atagataacg ctttacaaag ggttaagaga aaattagaaa aacatcttga aaacagaaat
    31321 gattaatagt aaaatactta ccataagctt attgtgagca aaattaattt atatcgaaag
    31381 ataagggagg aaattcaaaa tggctaaagc taaatacgaa agaacaaaac ctcatgttaa
    31441 tatagggaca ataggacacg tagaccacgg taaaactaca ttaacagcag caataacaaa
    31501 aacattatat gacagatatc aattaggaga agcagtagat ttcgcaaaca tagataaagc
    31561 tccagaagaa agagaaagag gaatcacaat atcaacagca cacgttgagt atgaaacacc
    31621 aaatagacac tatgcacacg ttgactgccc aggacatgct gactacgtta agaacatgat
    31681 aacaggagca gcacaaatgg acggagcaat attagtttgt tcagcaacag atggaccaat
    31741 gccacaaaca agagagcata tactattatc aagacaagtt ggagtaccat atatagtagt
    31801 attcttaaac aaatgtgaca tggtagatga tgaagagtta ttagagttag tagagatgga
    31861 agtaagagat ttattaacag aatatgattt cccaggagat gacactccaa tagtaagagg
    31921 ttcagcatta atggcattag aagatccaaa gagtgagtgg ggagataaga tagtagaatt
    31981 attcgagcaa atagatgagt atataccagc tccagagaga gatacagata aacc
//
LOCUS       DAFAZV010000048        31386 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.048, whole genome shotgun sequence.
ACCESSION   DAFAZV010000048 DAFAZV010000000
VERSION     DAFAZV010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31386
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.048"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(382..1278)
                     /locus_tag="KOU88_003061"
     CDS             complement(382..1278)
                     /locus_tag="KOU88_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK3212917.1"
                     /translation="MKDKNTYFNRKGQENFIDIFLKDDIKKGANFKRHWHEHLQIYYF
                     IDGIAYLECGLDNFKVVPGNIVIANSNELHYLESLSDNLKFYSIRIEPTFLFSNQVDL
                     LQTKYLAPLALNHIVFNNLIQNDSLILKCITTILDEYHNKEVGYELSIKANIYQLIVL
                     LLRSHIDKIYSEDEFIKRKYSLEKFECIFDLIEEKYMDKITLKELASHVNLSAHHFCR
                     TFKQITGKTTIDFINGIRLDKAIYYLKETDLNMTEIAMRCGFDSINYFSRLFKRNYNI
                     SPTKYRNEHKEVSNVILKEDMK"
     gene            1419..2846
                     /locus_tag="KOU88_003062"
     CDS             1419..2846
                     /locus_tag="KOU88_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3212918.1"
                     /translation="MTNSFKKDDNRKKITVLFVVIAMTFMATLDSSIINVALPVLASK
                     LNVSLASIEWVIASYSIIICSTLLFFGRLGDIIGKSRVFQVGTILFTSASLLCGLSNS
                     LTLLIVCRFIQGIGASAYMANNHGIITELFPKESRGKALGILVTAVAIGNMVGPSVGG
                     FILSIFDWNVIFFINIPIGLIVIFLNTKFLPNSKKSSENMDKTGAILQFLGTTLFFSA
                     LISAQQTGLLNPYILIALLLSIIFIILFLILEKKHPQPLLDLEIFRNFKFSLNLICAL
                     TSFICIASSSILIPFYLQSTMKLPPIQAGLFMILSPLILAIFSPIFGNISDKIKSEKI
                     ILIGLLVMSFGFFLMSRLKESSALILFVIYISIISIGQAIFQPANNALIMSSCSRSKL
                     GVVGSINSLVRNLGQVIGITISTTLLYNFMSIKAGYRVNDYVINNDKIFVFGMRNVYI
                     IVTLVCLIGAILIGFYLFKYNKNEQ"
     gene            complement(3042..5636)
                     /gene="clpB"
                     /locus_tag="KOU88_003063"
     CDS             complement(3042..5636)
                     /gene="clpB"
                     /locus_tag="KOU88_003063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBK3212919.1"
                     /translation="MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDG
                     LIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGADSQGVSATRKINEVLIKAESISK
                     EFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE
                     GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKT
                     AIVEGLAERIVRGDVPEGLKDKIVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDG
                     KIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATTFDEYRKYIEKDKAL
                     ERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLP
                     DKAIDLIDEAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQ
                     KEIAELKSKNDEMTAKYEKEKSQILDIKNLKAQLDEAKGKAEKYEREYDFNKAAEVKY
                     GEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVEGEREKL
                     LKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKT
                     LARNLFDSEDNIIRIDMSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVIL
                     FDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTLIIMTSNIGSNYLLEAGGNIT
                     ETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDIT
                     IEVTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKD
                     ENIEVLVK"
     gene            complement(5673..6269)
                     /locus_tag="KOU88_003064"
     CDS             complement(5673..6269)
                     /locus_tag="KOU88_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212920.1"
                     /translation="MSLKLDRNVLQWFDYVFENEKTSLRHYNFNCTLKEISSTSLNKV
                     AFILEKNNSKYWKLYFEIPAEVTLKLKQNIHPLFREYIYEQISLYNNNQIYNFVNSNI
                     LKVFNNIAIYQYNILENLYTIDFKKSFIDKCQYLLIGEKRLIDEDLYLIAKSKEVFDF
                     FNSDGTFNLTLSFDIQKNENLLDSLLELRKSIIINERI"
     gene            complement(6286..6690)
                     /locus_tag="KOU88_003065"
     CDS             complement(6286..6690)
                     /locus_tag="KOU88_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication/maintenance protein RepL"
                     /protein_id="HBK3212921.1"
                     /translation="MDKTLKKDLNQEYTESKSLVMNKSKYMNVCFKNYIKVVEGMYTK
                     RDLIPLKLINSMDKNNKIRKTLYELSCEFEYPKTSLSSLFTELKKMDFLQRVKNGEYM
                     INPHIAYKGSRADKESLLAEYNQIKRPNKVSK"
     gene            7057..7431
                     /locus_tag="KOU88_003066"
     CDS             7057..7431
                     /locus_tag="KOU88_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3212922.1"
                     /translation="MNIVISNSSGKPIYEQITTQIKSMIISGELPEGSALPSMRLLAK
                     ELRISVITTKRAYSDLERDGFIETVTGKGSFVSSKNMDFVKEEQFRLIEEYLQKAVDT
                     AKSSDITYDELKDILFLLYKGE"
     gene            7428..8291
                     /locus_tag="KOU88_003067"
     CDS             7428..8291
                     /locus_tag="KOU88_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3212923.1"
                     /translation="MISMDAITIKNLNKTYKDFSLQDISFSVPKGSVMGFVGENGAGK
                     TTTLKAILNLISYDSGNIEIFGLDSKKNEKEIKEQIGVVFEGSNFHENLNTDHVSKIM
                     SKIYKNWNDTLFKDYLKKLRVPDNKLIKEFSKGNKMKLSIAVALSHKPKLLILDEATS
                     SLDPIVREEILDIFLDFIQDEEHSIILSSHITSDLDKIADYITFIHKGKIVFSENKDE
                     LIDTMGVLKCKPSDFDNLSREDYSYYRKSQFGYEVLLKDKHRFISRHPNCIVDNTSIE
                     EIMLFYVRGDK"
     gene            8291..8929
                     /locus_tag="KOU88_003068"
     CDS             8291..8929
                     /locus_tag="KOU88_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBK3212924.1"
                     /translation="MKGLILKDLLNLKGNIKFILLFIIMFGFMSSLGDGNVNNFIGVI
                     IVLCTTMIVSTFSYDDLNKWDSYVLTMPINRNDIVLSKYLTMLIFSFIGVLVSLIVSV
                     TIGYFKNTLILNETLLINALILSISVCFGSLILPLIYKFGTERARLLMILCFLVPTLA
                     LLVFKSILENISSPISIEIILNTLVYSLPFVAILLFVISYFISSKIYSKKEV"
     gene            9421..9834
                     /locus_tag="KOU88_003069"
     CDS             9421..9834
                     /locus_tag="KOU88_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3212925.1"
                     /translation="MELEITEKIEKQDEDTIFQGLLKYNLARLEDKNPVDLGIYIRDK
                     AGKIVAGFIGVTHGNWLSIKYLWVSEKLRYKGTGSQLLYKAEKIAKERGCKYVFLDTF
                     SFQAPKFYEKFGYHKVFSLENYPLTGKRYYYRKIL"
     gene            10025..11242
                     /locus_tag="KOU88_003070"
     CDS             10025..11242
                     /locus_tag="KOU88_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallo-hydrolase"
                     /protein_id="HBK3212926.1"
                     /translation="MLGKKCMDYLQTLGKISSTTNGLTRLILTQEHKKSIDLISSWME
                     GLNLDIEIDDIGNVIGTYKSSFPNAPTLVVASHQDSVKCGGIFDGMLGIIVPLVGLEE
                     AKHNNRSYPFNIKLIAFAEEEGTRFETSLMGSKVFAGTFKEELLKSVDENGITLEEAV
                     TKFGFNTKNLTNLHPRKDVDAYLEFHIEQGPVLENESLPAGIVSSITGFKSFKISVNG
                     KSGHAGTLPMNMRLDAGCCACECVLAIEKVAKTTTDLVATVGKMNFYPSSSNVVPERA
                     EFTLDVRSCSQEILDNSVEKIFNEISHICENRKLNYTSELAFENVPVPCSNKITKIIE
                     KSFIDLNLNPFYIYSGAGHDAQEMDNITDIGMVFIRCAGGVSHNPNESVSVDDLDTAV
                     KIFLKILDNLDLK"
     gene            11404..12102
                     /locus_tag="KOU88_003071"
     CDS             11404..12102
                     /locus_tag="KOU88_003071"
                     /EC_number="5.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBK3212927.1"
                     /translation="MNEKLIGILAGMGPRSTAPFVDLIIDECQSQYGAKYDDEFPKMM
                     IYSLPTPFYIDRPINHDLMKETIIDGLQKLESTGVNFIAMPCNSAHIYFKELKESINI
                     PILNIVEETVKKLPTISQKVTLFSTSSTFESTIYQNGIIHNGHEFIFKDEWQIKLNNL
                     IQNIKMDKENPHNIDIWNKLIEDVKNESIENIVIACTDLNVVLEKSYPSINIVDSSKC
                     LAESVVNKYLKLVK"
     gene            complement(12322..12939)
                     /locus_tag="KOU88_003072"
     CDS             complement(12322..12939)
                     /locus_tag="KOU88_003072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4878 domain-containing protein"
                     /protein_id="HBK3212928.1"
                     /translation="MKKIILALTTFLLAISLTACSSAKPEDTIDSFFNSAKKFDFEGM
                     NKVMENNDEKYKDILKELDTKDPNAQYVLDYLKQNASKITYTIKDSEVKGDKATIKVE
                     CKFIDSTPLLQEIVAEAFTKMIGMSFSGQDLTDEKTTEMLVSIMKEKQKSVKETYVTK
                     NVEFECSKKDNKWIISSVNDAVADVLLSNLVTAGQEFSNSMNTLE"
     gene            complement(13066..14088)
                     /gene="argF"
                     /locus_tag="KOU88_003073"
     CDS             complement(13066..14088)
                     /gene="argF"
                     /locus_tag="KOU88_003073"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBK3212929.1"
                     /translation="MNNISLKGKSFLTLKDFTKEEIRYLLTLSSYLKTKKKVGIKGDL
                     LQGKNIALLFEKTSTRTRCSFEVAAHDEGAHVTYLGPNDCHMGKKESVSDTAKVLGRF
                     YDGIEFRGFKQETVESLAKYSGVPVWNGLTDEYHPTQILADFLTVIENVDKDLNKVKF
                     VYVGDARNNMGNSLMIGCAKMGIHFVALAPKELWPNEELVKEMKEIAKKSKGDIMLTE
                     NIDDVKGADVIYTDVWVSMGEEEQYEARINQLKDYQVNMDMIKKTENENVIFLHCLPA
                     FHDLETKVAQEIYEKFGLSELEVTNEVFNSKYSKVFEEAENRMHTIKAVMVSTMTDVN
                     MNNNLI"
     gene            complement(14197..15384)
                     /locus_tag="KOU88_003074"
     CDS             complement(14197..15384)
                     /locus_tag="KOU88_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HBK3212930.1"
                     /translation="MNNDNTISKWNEYFIDTYNQPNFVIDYGEGSCFFDTNGNKYIDF
                     TSGYGVSSLGYSNSNLKNALKEQVDKLLHTSNLYFNEPVLYSGEKIINSSGMAKVYFC
                     NSGTEANETAFKIARKYSSDKYGNGRGTIISLKDSFHGRTMMSLMATGMDKYHKYFYP
                     LPEGFKYIERNNIEDLKNNLDSTVCAIILEAIQGEGGVNVLEKDYVLEIVKICQEKDI
                     VVIFDEVQCGIGRTGKLFGYEYFDVKPDIVTVAKGLGAGIPVGGVLVNKKLSKVLGKG
                     DQGTTFGGNLLAMVAASVVLDEISKDGFYNEVLEKGNYIRKSIESFNNKVILKTKGIG
                     LMIGIETNIESSIIEEKARKKGLLILTAGKNVLRFLPPLTISYKEIDEALEILKDILL
                     EIN"
     gene            complement(15414..16274)
                     /gene="argB"
                     /locus_tag="KOU88_003075"
     CDS             complement(15414..16274)
                     /gene="argB"
                     /locus_tag="KOU88_003075"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBK3212931.1"
                     /translation="MINIEKANTLIEALPYIEKHQGKTIVVKYGGSAMKKDGLKESVM
                     EDLVLMSYVGINIVLVHGGGAEINKMLAKVDIESKFVNGLRYTDEETMEIVKMVLAGK
                     VNKDLVNKIHTKGGKAVGLCGIDNNMILCDPYKNYELGFVGEIKKVNVELIESCLKSG
                     YISVIATIGVGDDGETYNINGDTAASAIAKELNADKLILLTDVPGLLREPDEEKSLIT
                     EVILEDVDKLFEEGIITGGMIPKIEGCVDALNNGVNRVHILDGRVPHSIITELFTDSG
                     IGTLIRKETE"
     gene            complement(16289..17506)
                     /gene="argJ"
                     /locus_tag="KOU88_003076"
     CDS             complement(16289..17506)
                     /gene="argJ"
                     /locus_tag="KOU88_003076"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HBK3212932.1"
                     /translation="MEIIKGGVTVSEGFFASGIHCGLRKNKEKRDLALVYSDVLCDAA
                     AVVTQNKVKGNPVYVTQEHIKNGKAQAIIVNSANANTFNGKEGLINAYKMAKFTSDKL
                     NIKESDVLVASTGVIGKPLNIDLIEENMDELVNNLSKQGHIGAREAIMTTDIIKKEIA
                     VAIMYGDKKITIGGMAKGSGMIHPNMATTLGFITTDANIDGVLLKEALKIAVDKSFNR
                     VSVDGDTSTNDMVMILANGKAKNDRINKKDEHYQVFLSALTYVCIELAKLVAKDGEGC
                     TKLIECYINGALSEEHAVKLAKTVISSSLVKTAVFGADANWGRILCALGYAGEEIDME
                     KVDIIFESMKGYIEVCKNGNGLDFNEEKAKKILEDDEISILVDLNMGNARGNAWGCDL
                     SYDYVRINGSYRN"
     gene            complement(17547..18581)
                     /locus_tag="KOU88_003077"
     CDS             complement(17547..18581)
                     /locus_tag="KOU88_003077"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBK3212933.1"
                     /translation="MNKIKVGIIGATGYVGAELIRLLMNHDKVEVTAIGSNSYVGKDI
                     VDIYPSIGYKNNMICIENEKVIDMCDVVFTALPHGVSEKFVIKAIKSKKKVIDLGADF
                     RIKDEEVYSKWYGVSFIDKILHKKAVYGLSEIYKEDIKDADIIANPGCYPTSISLPLM
                     PLLSSKLIKNNNIIIDSKSGLTGAGRELSISSHFTEVNENITAYKIGKHRHTPEIEQN
                     LSESCKEKVSVVFTPNLIPVNRGILSTIYCTKEDNISINDIHRKLTDYYEFKEFIEIL
                     PLDKVASLKNVRFSNKCVISLHENGDTLIICSAIDNMIKGAAGQAIQNMNIIFGIEEN
                     TGLKNIAPSF"
     misc_binding    complement(18835..19048)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(19351..20442)
                     /gene="ytvI"
                     /locus_tag="KOU88_003078"
     CDS             complement(19351..20442)
                     /gene="ytvI"
                     /locus_tag="KOU88_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBK3212934.1"
                     /translation="MNEQDHTSYQNKQRFLINFCYLVVILGLLMLLGKYAFSVLLPFV
                     FAFLIASLLNKPVLYISEKLLIKRGIVATISVFLFFLIAGIIVSVIGTYLIYGIKEIF
                     HFLPTMFEELVIPLTETVIKEVELFSGSFNFSFIELIEANMPVLMNEMSVFIVSLSNN
                     IVSGITDIVSSVPLLFMKTIITIVASIFIAIDYPTIKRFIVLQIPKNKSYLLAEAKAF
                     TIDTIIKCGFSYLLIFAITFSELYVGFAIINISYAGIIALFIALLDILPVLGTGSILI
                     PWCIISLFLGDYSMALGIALLYIVITIIRNIIEPKLVGKHMELHPVLALASMLTGLHF
                     FGFIGLFGIPLLIAFLKKLNDKEIIHILH"
     gene            complement(20457..21848)
                     /locus_tag="KOU88_003079"
     CDS             complement(20457..21848)
                     /locus_tag="KOU88_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase family protein"
                     /protein_id="HBK3212935.1"
                     /translation="MKRRLAGEWEPIKGVMLAWPPFLPHKYIVDLTQNYSVYMCVPNK
                     EEIEIAKYYLSKWGGNLKNLIFCIAPQGFDTPWVRDWGMHPIFDENGKLFLAGAEYKM
                     STPFVSINKPEIMFDCEHNLLTTNSYEQKEDQSQELIAKQIGLPFMKLPYALTGGNLM
                     SDGFNKLMSMHILQTENRAKGISDEEFFSMVARDTGMNEYYIFSNFADYGLQHIDCYL
                     KIIDEETLLVSRTPKEHYLYERYEKILEEVKKVETRYGRPFKIFRIDIVPFQKDSDEL
                     TAYVNSVILNSRVYVPMYGIEQDKIAIKQWQNALPGYEIKGYEFDFEKEPDIIKNRTG
                     YVRTGWGNEDVIHCRTRAIWDENMLYISVKRLEEIVSENDALEVTIQIVDYSKAGLDY
                     ENCRLFYRYYGFQTWESIMLEETTEAEIFFANMIGKSGDMIEYFVQAKSCSGMCETMP
                     PVAPKGTYKVTIK"
     gene            complement(21867..22406)
                     /locus_tag="KOU88_003080"
     CDS             complement(21867..22406)
                     /locus_tag="KOU88_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3212936.1"
                     /translation="MSLTIQKVTSYFKDLEKFEELNNEAFPDEERMSIQEMLNLVQSK
                     KIEVSALYDKQQFIGFYVLVIENHIGYILFLAISPEQRSKGYGGKALSLMKKQYPNCQ
                     IVLDMETIEDSAPNLQQRILRKQFYLQNGFYETEYLMEYKGLEMEVLCNQKTFQKNEF
                     ETLLKNLKIREIPFHLWKK"
     gene            complement(22427..23752)
                     /locus_tag="KOU88_003081"
     CDS             complement(22427..23752)
                     /locus_tag="KOU88_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009295908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3212937.1"
                     /translation="MIQLSDNFNYKRLLKFTFPTIIMLVISSIYGVVDGYFVSNFVGK
                     TAFTAVNFIMPFLLILGCVGFLFGTGGGALIAKTMGEGKKEEANEQFSLLIVTSAGCG
                     IILAVLGIVTMPWIASAMGADGQLLTDSILYGCVVIIAIPAYILQCEFQCLFATAEKP
                     KLGLYVAIMAGITNIVLDALFITVFKWGLVGAALATAIGQYVGGIIPLLYFSRQNNSL
                     LKFKKPKFDCDVLKKTVANGSSELMTNVSTSVVSMLYNAQLLKYAGEDGVASYGVLLY
                     VALLFQAVFIGYSVGTAPIISYHYGAKNYDELKNLRKRSLIVIICFAVFMFIIGEFLS
                     KPIAFIFVGYDNNLMEMTLRAFMIYSFSFLFSGFGVFGSSFFTALNDGLTSALIAFMR
                     ILVFQVVSVLIFPIFWGVNGIWFSIVGAEILATIMTAFFIIKKQKKYHY"
     gene            complement(23749..24372)
                     /locus_tag="KOU88_003082"
     CDS             complement(23749..24372)
                     /locus_tag="KOU88_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase-like family protein"
                     /protein_id="HBK3212938.1"
                     /translation="MKIITISREFGSGGRELGKQLADILNFDYYDKEIITAIARKKKI
                     DENYVSYILENHGWRNVPLTMCTSFTNILSMQSMKTDLLIEQSNVINQIASTGKDCVI
                     VGRNADILLKKYQPFNVFVCANMNFKIQRCIEKKLNNEHISKKELERKIREIDKNRAR
                     SREFFTSSLWGNQTSYHIIVNTSEWNIKHLSYAIANFSEYWFRRYEQ"
     gene            24464..25273
                     /locus_tag="KOU88_003083"
     CDS             24464..25273
                     /locus_tag="KOU88_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3212939.1"
                     /translation="MIKKLYKTSEFAELCGVKKHTLYHYDEIELLKPSITHENGYRYY
                     TIDQFEKFNIISVLKKAGTPLEEIKQYLNDLDTNTFLNVLHRKLMDLQEEVKKIEKMC
                     SMLRNVISTMEIHLNVNTEKIEIVNCEEEYLIATKIPEAVLTDEKTMLQGIGNHLQYC
                     LLHDYNFHVGEIVLEKNIKQGIFRESYYYSLIKNKVDDERLFIKPKGNYAVMYHQGSY
                     DSLYKTYQNMKNQLEEQGYHIVGNIYEEDLIDYLSEHNAENYIQKISIQVI"
     gene            25707..26069
                     /locus_tag="KOU88_003084"
     CDS             25707..26069
                     /locus_tag="KOU88_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004843367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212940.1"
                     /translation="MEIDYKAIGQRIKIARIKKGITQESVANIINMTPSHMSNVETGK
                     TKVSLPTLIAIANALSVSVDTLLCDNVLSSKVIFEKEAKDIFSDCDEYEIRSLVELLK
                     SAKTVIRKDREIRKQFEK"
     gene            complement(26419..26976)
                     /locus_tag="KOU88_003085"
     CDS             complement(26419..26976)
                     /locus_tag="KOU88_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3212941.1"
                     /translation="MRVSREIVIQATSDIVNKDGLNKVSLKVIAEKLGIRTPSLYNHI
                     ESLDDLLLEVAHKGMREMNSQMIKAAIGNFGDTAIKCISIAYFNFIISNPGVYETIQW
                     ATWHGNNETLEIFDEYKSLLEKLILSCNLNTKNTGEVLNLIMSVLHGYSTLQLGKSLL
                     SKEEAIKGLVDSIDTVLLGIHKKYD"
     gene            27234..27932
                     /locus_tag="KOU88_003086"
     CDS             27234..27932
                     /locus_tag="KOU88_003086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3212942.1"
                     /translation="MEKKYFEIHGVPSILWGNPSSKLYIYIHGQCGNKEEAEAFANIA
                     VPHECQVLSVDLPEHGERKREKNSFNPWHVVPELVSIMEYAKCHWNQISLYANSIGAW
                     FSMLSFEKENLRECIFVSPILDMQQLISNMMLWANVSEEQLKHELIIPTSFGHTLSWE
                     YLQYVKQHPITQWNVPTKILYGKHDELTEIGVVEKFVEKFNCNLTIIENGKHWFNTPQ
                     ELNSLYEWLNTLVK"
     gene            28955..29422
                     /locus_tag="KOU88_003087"
     CDS             28955..29422
                     /locus_tag="KOU88_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBK3212943.1"
                     /translation="MITKFFSNILSVFLYFLLSLLGVAGIIFLCMIPMFLYDFSSDKV
                     IALIARILYFSDYFIVILFLIFIINSTKYSPFVLENVKRFKVMGFCLLINTIIECING
                     YNLNTNNIRIFGTDSGGISPLMIISFIFALMCFVIAETFDKAIKIKEDNDLTI"
     gene            29433..29648
                     /locus_tag="KOU88_003088"
     CDS             29433..29648
                     /locus_tag="KOU88_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212944.1"
                     /translation="MAIVVNLDVMMAKRKISLKDLAEKIDITNANLSILKTGKAKAIR
                     FTTLNEICKALDCQPGDILEYVEDEND"
     gene            complement(30419..30703)
                     /locus_tag="KOU88_003089"
     CDS             complement(30419..30703)
                     /locus_tag="KOU88_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212945.1"
                     /translation="MLVYNKSFYPNDIFPRLDFSKIKKQLKLIDNDLSDFGSICIIEK
                     EHYTISVNSIGEINVYYDLEYENKVYRIVYEIEKLFKSQVGRFSISTYRN"
     gene            complement(31151..>31386)
                     /locus_tag="KOU88_003090"
     CDS             complement(31151..>31386)
                     /locus_tag="KOU88_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="HBK3212946.1"
                     /translation="IKLTPTENRLLNYFIENAEKTLTIKEIYEHVWMNEYLDDNYSVV
                     VAVSGLRKKIEKDYKNPQKIITIREVGYYFNKI"
BASE COUNT        10870 a         4881 c         3561 g        12074 t
ORIGIN      
        1 tatataattt ttttatattt atttgacttt cttttaattc tttaggatgg atttaaattt
       61 tctataaaaa tcatactatt ttagctgttt acttgcttat ttaatagttt tatttctttg
      121 attaaatatc tttcagaatc taagccagat gtctcaaaaa aactgattta taatataatc
      181 attttttctg ctattcttat ttttccaatt ttagtttcat attaaaatat acttttcata
      241 gacactacat tctttcatac tcattttcac atttaactat acaagtagtc ttactcattt
      301 atgtactata ctttattaat atttattaag aaaaactcaa agatttaaaa atatatattt
      361 tctataaagt atatttatga attatttcat atcttctttt aaaataacat tactaacttc
      421 tttatgttca tttctatact tagttggaga tatattataa ttccttttaa ataagcgact
      481 aaaataattt atgctatcaa agccacatct catagcaatt tctgtcatat ttaaatctgt
      541 ttcctttaaa taatatatag ctttatcaag cctgattcca tttataaaat cgattgtagt
      601 cttacctgtt atttgcttaa atgttctaca aaagtgatgt gcactcaagt tcacatgact
      661 agcaagttct tttaatgtaa ttttatccat atatttttct tctatcaaat caaagataca
      721 ttcaaatttt tctaaagaat actttctttt tataaattca tcttcagaat atattttatc
      781 aatatgactt cttaataaga gtactattaa ttgatagata ttagctttta tagataactc
      841 atatccaact tctttattgt gatattcatc aagtatagtt gtaatacatt ttaaaatcag
      901 agaatcattt tgaattaaat tattaaatac aatatgattt aaagccaatg gtgctaagta
      961 cttggtttgt aacaaatcaa cttgattact aaaaaggaat gtgggttcaa tacgaatact
     1021 atagaatttt aaattatctg ataagctttc taaataatgt aattcattac tgtttgctat
     1081 tacaatattt ccaggcacta ccttaaaatt atccaatcca cattcaagat atgctatacc
     1141 atcaataaaa taatatattt gtagatgctc atgccaatgt cttttaaagt ttgctccttt
     1201 tttaatgtca tcctttaaaa aaatatctat aaagttttct tgacctttcc tgttaaaata
     1261 tgtattttta tccttcatta ttcccccctc atcaaaatag tgctaattat aagcaatata
     1321 gttattgtat tcattatttc atatcgctat tatataaaat gtaactatca ttgtaaacat
     1381 taacataatg cagtcattat aataaggagg taataaaaat gacaaactct tttaaaaaag
     1441 atgataatag aaaaaaaatc acagttttat ttgtagtcat tgccatgact tttatggcaa
     1501 cattagattc tagtattata aatgttgctc tcccagttct tgcaagcaaa ctaaatgtat
     1561 ctctagcatc tattgaatgg gtaatagcaa gttactcaat tattatttgt tcaacactat
     1621 tattttttgg aagacttgga gatattattg gtaaatcaag agtatttcaa gtaggtacta
     1681 ttctctttac atcagcttca ttactatgtg gattaagtaa ttctttaact ttacttatag
     1741 tttgccgctt tattcaagga ataggcgctt ctgcctacat ggcaaacaat catggaatta
     1801 tcacagaact atttccaaaa gaaagcagag gaaaagccct agggatttta gttactgcag
     1861 ttgctattgg aaatatggtt ggaccatctg tgggaggatt tattttgtca atatttgatt
     1921 ggaatgttat attttttata aatattccaa tcggtcttat tgtaatcttt ttaaatacaa
     1981 aatttcttcc taatagtaaa aaatcttcag aaaatatgga taaaactggt gctatacttc
     2041 aatttttagg aacaacatta ttttttagtg ctctaattag tgctcaacaa acaggattac
     2101 taaatccata tatattaatt gcactattat tatcaattat ttttattata ttatttttga
     2161 tattagaaaa aaaacatcct caaccgcttc ttgaccttga aatttttaga aattttaaat
     2221 tttcattgaa tttaatttgt gctcttacat cattcatttg tattgcatca tcaagtattt
     2281 taattccatt ttatttacaa agtactatga aacttccccc tattcaagca ggtttattta
     2341 tgatactatc acctttgatt ttagccattt tttcacctat atttgggaat atatcagata
     2401 aaattaagtc agaaaaaatt attttaattg gtcttctcgt tatgagtttt ggattctttc
     2461 taatgtcaag attgaaagaa agttctgccc ttattttatt tgtaatttat atatcgataa
     2521 tatcaatagg acaagctata tttcaacctg ctaacaatgc tttgataatg tcaagctgtt
     2581 ctagaagtaa gctaggagtt gtaggaagca taaattccct tgtaagaaat ttaggacaag
     2641 ttataggtat tactatttct acaacacttt tatataattt tatgagtatt aaagctggat
     2701 atagggtcaa tgattatgtg attaataatg ataaaatatt tgtatttgga atgagaaatg
     2761 tttatattat tgttacactt gtttgcttaa taggtgcaat attaattggc ttttatttat
     2821 ttaaatataa taaaaatgaa caatagtttt tataattata ttcaaattat gattatatta
     2881 taagaaattt actaaaatac ttcctttgag ttaaatttaa tttggacata ttgacttaaa
     2941 aatgttttat taatttgata aaatatttct tttcctatag tttataaata aaaatcagct
     3001 gagcaaaata tttagtatat tatgctcaac tgattctttt attatttaac taaaacttca
     3061 atattttcat cttttccatc tataactata gtacatccat tatacacatc tccagcaata
     3121 agtttctttg caattatagt ttctaatgta tttcctatat atctcttaag aggtcttgct
     3181 ccatatacag ggtcatatcc ttctctcacc ataacatctt ttgctgaatt tgtaacttca
     3241 atagtaatat ctttttcttt taatctattt tttaaatctt tcataaatat atctataatt
     3301 ttcttgatat tttcttggtc taaaggctta aacattataa tatcatctac tctgtttaaa
     3361 aactcaggtt taaatctatg cttcatttca ttcattacta aattgttagt agtctctgtt
     3421 atatttcctc ctgcttctaa tagataatta cttcctatat tagaagtcat tattataaga
     3481 gtatttttaa agtctactgt cttaccttta ttatcagtaa gtctaccatc atctaatatc
     3541 tgtaagaaca tgttaaatac atcctcatgt gctttttcta tctcatcaaa tagtattaca
     3601 gaataaggag cacgtctaac tgcttctgta agttgaccac cctcttcata tcccacgtac
     3661 cctggaggag gtccaactag tcttgataca gcatgttttt ccatgtattc agacatatct
     3721 attcttatta tattatcttc actatcgaat aaatttctag caagagtttt tgcaagttca
     3781 gttttaccaa cacctgtagg gcctaagaaa ataaatgaac caattggttt tctttcatct
     3841 tttaatcctg ctcttgcacg tattactgca tttgaaactg ctgtaactgc ttcatcttgt
     3901 ccaataactc ttttatgaag ttcatcttct agtttaagta atttttctct ttctccttca
     3961 actagtttag ttactggtat acctgtccac tttgatacaa tgctagatat ttcttcttca
     4021 gtaacttctt cttttaaaag agaattttca gaaccatcat tcatattttc ttcgtactgc
     4081 tttatttgtt cttctaactt aggtatttca ccatatttaa cctctgctgc tttgttgaaa
     4141 tcatattctc tttcatactt ttcagcttta cctttagctt cgtctaattg agcctttaag
     4201 tttttaatat ctaatatttg actcttttct ttttcatatt ttgctgtcat ttcatcattt
     4261 ttagatttta actctgctat ttctttttga atatcatcca atcttgattt acttttatca
     4321 tcattttctt taagtaatgc ttctctttca gtttctaatg taaataactt tcttctaaca
     4381 acatctaatt ctgttggcaa tgaatctatt tcactacgaa tcatagctcc agcttcatca
     4441 attaaatcaa ttgctttatc tggtaaaaat ctatcttgta tatatctatg agaaagtttt
     4501 gctgctgcta caatagcatt atcatgtatt cttactccat gatgtatctc aaatctttct
     4561 tttaaacctc taagtataga tattgtatct tcaacagtag gttcttctgc aattacaggc
     4621 tgaaaacgtc tttcaagagc cttatctttt tctatatact ttctatattc atcaaaagta
     4681 gttgcaccaa tacagttcaa ttcacctctt gcaagcatag gtttaataag attacctgca
     4741 tccattgaac cttctgtttt accagctcca acaatagtat gaatctcatc tataaacagt
     4801 ataatttttc catcagaact ttgaacttct tttaaaactg cctttaatct ttcttcaaat
     4861 tcacctctat attttgcacc agcaattaaa gctcccatat caagtgagaa tacaatctta
     4921 tcttttaaac cttctgggac atctcctctt actattctct ctgctaaccc ttctacaatt
     4981 gcagttttac ctacacctgg ctcaccaatc aatacaggat tattttttgt tcttcttgat
     5041 aaaattctta taatccttct tatttcttca tctctcccaa ttacagggtc taatttattt
     5101 ttcttggcta aatctactaa atttgttcca tatctagcaa gtgcatcata tgtgccttct
     5161 gggtcttgtg tttctactct ttgactacct ctcacttgtg ataaaatatt taaaaagtca
     5221 ttcttattta tattatattg ttttaatatt ttaccaacag ctgattttga ttctgtttcc
     5281 atcattgcaa gcataacatg ctctacactt atatatgaat ctttaaattc tttagaaata
     5341 ctctctgcct ttataagcac ctcatttatt tttctagtag ctgatactcc ttgtgagtca
     5401 gcaccttctc catatacttt tggaagctta tcaatttcaa agtttacagt atttctcaaa
     5461 gaatcaattg atatattcat tttttcgatt atatttggta tcaatccatc ctcttgatta
     5521 ataagtgctg agaaaagatg aattacatct acttgttggt tatgattttt tactgcttcg
     5581 ttataagcct catttaaact tttttgaact cttaaagtca ttttttctac gtccatataa
     5641 atccctccat tttaatatta tatccaaata aattaaattc tctcatttat aattattgat
     5701 tttctaagct ctaaaagact atcaagtaaa ttctcgtttt tttgtatatc gaaactcaat
     5761 gttaaattaa atgttccatc tgaattaaaa aaatcgaata cttcttttga ttttgctatt
     5821 aaatacaagt cttcatctat aagtcttttt tcacctatta ataaatactg acatttatct
     5881 ataaaactct ttttaaaatc aatagtgtat agattttcta aaatattata ttgataaata
     5941 gcaatattat taaacacttt taatatgttt gaatttacaa aattgtaaat ttgattattg
     6001 ttatacagtg atatttgttc gtatatatat tccctaaata aaggatgaat gttttgctta
     6061 agttttaaag taacttcagc tggtatttca aaataaagct tccagtactt agagttattt
     6121 ttttctaaaa taaaagctac tttgttcaaa ctggtagaac taatctcctt tagtgtacaa
     6181 ttaaaattat agtgtctcaa actagttttt tcattctcaa atacatagtc aaaccactgt
     6241 agaacatttc tatcaagttt taaactcata taaaaacctt cttccttatt tactaacctt
     6301 attaggtctt tttatctgat tatattctgc taataaactt tctttatcag ctctactacc
     6361 tttatatgct atatgtggat ttatcatata ctcaccattt ttcactcttt gtaaaaaatc
     6421 catttttttc agctccgtaa acaatgaaga taaagaagtt tttggatatt caaattcaca
     6481 agataattca tataatgttt ttctaatctt attattttta tccatagagt ttattaattt
     6541 taatggaatt aaatccctct tagtatacat tccttctact actttaatat aattcttaaa
     6601 acaaacattc atatacttac ttttattcat aactaaactt ttgctctctg tatattcctg
     6661 atttaaatcc ttttttaatg tcttatccaa attaaatatc tcttctcact ctccttatct
     6721 ctaattgata atataaatat attacaaaaa aatatgtatg tcaaaactga aaatgcaaaa
     6781 agttcacctt ataagcaaac ttttatttag ctataagcta aactttatta tttttttaat
     6841 ttagtatttc caatttattg gcaggatttt tgaacaatat ttataaattt tttaaaaaaa
     6901 tttaaatcta tttaatatgg cagactttca taaaatacat tacatttatt aaatgtataa
     6961 tattggcaat tagttttttc taaaatcagt tgacatatta tatatatatt tatataatgt
     7021 gtatatacta tatatacaat ttaaggaggt gtcttattga atatagttat tagtaattcg
     7081 agtgggaagc caatatatga acagattact acacaaatta aaagtatgat tataagtgga
     7141 gagttaccag aaggctcagc tcttccaagt atgagactat tggcaaaaga acttagaata
     7201 agtgtaatta ctacaaaacg agcatatagc gatttagaac gagacggatt tattgagaca
     7261 gttactggta aaggcagttt tgtatctagt aaaaacatgg attttgtcaa agaagaacaa
     7321 tttcgtttaa ttgaagaata cctacaaaaa gcagttgata cagcaaaaag tagtgatatt
     7381 acatatgacg aattaaaaga tattttattt ttattatata aaggagaatg ataagtatgg
     7441 atgcaataac tataaaaaat ttaaataaaa cttataaaga ttttagccta caagatatat
     7501 ctttttcagt accaaaaggg agtgtaatgg gatttgtagg tgaaaatggt gcaggaaaaa
     7561 caactacatt aaaagcaatt ttaaatttaa tatcttatga tagtggaaat atagaaatct
     7621 ttggtcttga tagtaaaaaa aatgaaaaag aaattaaaga gcaaattggg gttgtatttg
     7681 agggaagcaa ctttcatgaa aatttaaaca ctgaccatgt ttcaaaaatc atgagtaaaa
     7741 tctataaaaa ttggaatgac accttattta aagactactt aaaaaaattg agagtaccag
     7801 acaataaatt aattaaggag ttttcaaagg ggaataagat gaaacttagt attgctgtag
     7861 ccttatctca taaaccaaaa ttattaatac tagatgaggc aactagttca cttgacccta
     7921 tcgttcgtga agaaatacta gatatatttt tagattttat acaagatgaa gaacactcta
     7981 ttatcttatc ttcacatatt acaagtgatt tagataagat agcagactat attacattta
     8041 tacataaagg aaaaattgta tttagtgaaa ataaggatga attaattgat actatgggag
     8101 ttttaaaatg taaacctagt gattttgata acctttcaag agaggattat tcatattatc
     8161 gtaaaagcca atttggatat gaagtacttc ttaaagataa acatagattt atctcaagac
     8221 atccaaactg tattgttgat aatacgtcta tagaagaaat tatgttattt tatgtgagag
     8281 gtgataaata atgaaaggtc taattttaaa agatttactt aatttgaaag gaaatataaa
     8341 gtttatactt ttattcatca ttatgtttgg ctttatgtct tctttaggag atggaaatgt
     8401 taataacttt ataggtgtta ttatagtttt atgtactaca atgattgttt caacattttc
     8461 atatgatgat ttgaataaat gggatagtta tgtacttaca atgcctatta atcgcaatga
     8521 tattgtatta agtaaatatt taactatgtt aatatttagc tttataggtg ttcttgtttc
     8581 acttattgtt agtgtaacta ttggttattt taaaaataca cttatattaa atgaaacact
     8641 acttattaat gcactaatct tatcaatttc agtatgtttt ggtagcctta ttctaccact
     8701 tatttataaa tttggtacag aaagagctcg tttattaatg attttatgct ttttagttcc
     8761 aacactagct ttattagttt ttaaaagtat tttagaaaat attagttcac ctatttctat
     8821 agaaattata cttaatacac tagtatattc tcttccattt gttgctattt tactatttgt
     8881 gatttcatat tttatatcat caaaaatcta tagtaaaaaa gaagtataaa atatactata
     8941 tatatttctg tatttaagta tttaaataaa atactatcga gtttattttg gtagtatttt
     9001 attttttaac tattaatctc tactaggtat ttattatttt attacttata tttaataaga
     9061 ctatttacta ctttctaatc ttatttatat aatttattca ttttataaat tgaactacta
     9121 atgatattat tgaacatagc aatagaataa catctaaaat agtttttttg tattaaatta
     9181 acttatttta atattcaaca atttaggttt actaaattta ttgatgattt ctttttatat
     9241 aacttaaact acatttttat ttaaaaaaat ttaatatcaa caatataaaa ttaagaataa
     9301 gtattattag tttgacatta gcataaatgc ctattagaat aatgttaaac tatattcttt
     9361 ctactgattt tattaaaaaa taccaatata caaaagatta tacaaggaga aagttcaaat
     9421 atggaattag aaattacaga aaaaatagaa aaacaagatg aagatactat ttttcaagga
     9481 ttattaaaat ataatcttgc tagacttgaa gataaaaacc cagtggattt aggaatatat
     9541 attcgagata aagcaggtaa aattgttgca ggttttatag gtgttactca tggtaattgg
     9601 ctttctataa aatacttatg ggttagtgag aagcttagat ataaaggtac tggaagtcaa
     9661 cttttatata aggctgaaaa aattgctaaa gaacgaggtt gtaaatatgt ttttttagat
     9721 acattcagtt ttcaagcacc taaattttat gagaaatttg gataccataa agtattttca
     9781 cttgaaaatt atcctctaac tggaaagaga tattattata gaaaaatact ataataataa
     9841 aaatcatatt tcatattttt aaattaaaac ttctgctctt cgtctacaga ctttatgttt
     9901 ttatatcatt attaatacta aaatagtatt ttactataca tacaaaatta tttgaaagtt
     9961 caaaaattat aagtataaaa gctaatctta gcttaaataa aaattatatt tttaggaggt
    10021 aaatatgtta ggaaaaaaat gtatggatta tctacaaaca ttaggaaaaa taagttcaac
    10081 aacaaatggt cttacaagac ttatcttgac tcaagaacat aaaaaatcta ttgatttaat
    10141 tagttcatgg atggaaggtt taaatcttga tattgaaatt gatgacattg gaaacgttat
    10201 aggtacatat aaatcaagct ttccaaatgc tcccacatta gtagttgcat ctcatcaaga
    10261 tagtgtaaag tgtggaggta tatttgatgg tatgttaggt ataatagtgc ctctagttgg
    10321 tcttgaagaa gcaaaacaca ataataggtc ttatcctttc aatattaagc taattgcttt
    10381 cgctgaagag gaaggaacta gatttgaaac ttctttaatg ggaagtaaag tttttgctgg
    10441 tacttttaaa gaggaacttc ttaaatctgt tgatgaaaat ggaattacac ttgaagaagc
    10501 tgtaacaaag tttggattta atacaaaaaa cttaacaaat ttgcatccta gaaaagatgt
    10561 agatgcatat ttagaatttc atattgagca gggtcctgtt ttagaaaatg aatctcttcc
    10621 tgctggaatt gtatcaagta ttacaggatt taaaagtttt aagatatcag taaatggtaa
    10681 gtctggacat gctggtacac ttccaatgaa tatgagactt gatgctggat gttgtgcctg
    10741 tgaatgtgta ttagctatcg aaaaagtagc taaaacgact actgatttgg ttgctactgt
    10801 aggaaagatg aatttctatc catcttcatc aaatgtggta cctgaaagag ctgaatttac
    10861 actcgatgta cgctcttgtt cacaagaaat tcttgataat tctgtagaaa agatatttaa
    10921 tgaaatatca catatatgtg aaaatagaaa acttaattat acaagtgaac ttgcttttga
    10981 aaatgttcct gtaccatgtt ctaataaaat aacaaaaatc atagaaaaaa gttttataga
    11041 tttaaatctt aatccttttt atatttatag tggtgctggc catgatgctc aggaaatgga
    11101 taatataact gatattggta tggtatttat aagatgcgct gggggcgtaa gtcataatcc
    11161 taatgaaagt gtctctgtag atgacttgga tactgctgta aaaatatttt taaaaatact
    11221 agataatctt gatttaaaat aattcttata taagaaagta tattaaaata tataatctaa
    11281 aaaatcactt tatatttata ttatataagt gtacaatata atctattata aaatataatt
    11341 ttatgctttt atagattttt attttataca taaatatatt tatatataaa ggagataatt
    11401 tttatgaatg aaaaattaat tggtattttg gctggaatgg gtccaaggtc aacagcccct
    11461 tttgttgatt taattattga tgagtgtcaa tctcaatatg gagcaaaata tgatgatgaa
    11521 tttccaaaga tgatgatata ttcattacct accccatttt atattgaccg tccaataaat
    11581 catgacctta tgaaagaaac tataattgat ggattacaaa agcttgaatc aactggtgta
    11641 aattttattg caatgccatg caattcagca catatatact ttaaagaatt aaaagagtct
    11701 attaatatac caatattaaa tattgtagaa gaaacagtta aaaaattacc tactatctca
    11761 caaaaagtaa ctcttttttc gactagttca acttttgagt ctacaattta ccagaatggt
    11821 ataatacata atggacatga atttatattt aaagatgaat ggcaaataaa attaaacaat
    11881 cttattcaaa atataaaaat ggataaagaa aatccacaca atattgatat ttggaataaa
    11941 cttattgaag atgttaaaaa tgaatctata gaaaatatag taattgcttg tactgattta
    12001 aatgtagttt tagaaaaatc atatccttca ataaatattg ttgattcatc aaaatgcttg
    12061 gctgaatcag ttgtcaataa atatctaaaa ttagttaaat aaatttttca tacactatat
    12121 tataaaaaat atatgttata agtttatttt aaatagtata gacttataac atatatcata
    12181 gtttcttgac aatatagaaa ttaaccatgt atttcattat attaataaaa aggataccaa
    12241 aaatggtatc cttcataaat atttatatgt ttatttataa aaataatcat atatttatta
    12301 ctttactaca cctaaacaat attattcaag tgtattcata gagttagaaa attcttgtcc
    12361 tgctgtaaca agattagata acaatacatc agctactgca tcatttactg aacttattat
    12421 ccatttatta tcctttttag aacattcaaa ctctacattt tttgtaacat aagtctcttt
    12481 aacgcttttt tgtttttctt tcataattga tactaacatt tcagttgttt tctcatcagt
    12541 taagtcttgt cctgaaaaac tcataccaat catctttgta aatgcctcag ctactatttc
    12601 ttgaagtaat ggtgttgaat ctataaattt acattctact ttgattgtag ccttatcacc
    12661 tttaacctcg ctgtctttta ttgtatatgt gattttagat gcattctgtt ttagataatc
    12721 taaaacatat tgggcatttg ggtcttttgt atctaattcc tttaatatat ccttatattt
    12781 ttcgtcatta ttttccatta ccttattcat gccttcaaag tcaaactttt tcgcactgtt
    12841 aaaaaaacta tcaattgtat cttctggttt tgcacttgaa catgctgtta aagatattgc
    12901 taataaaaaa gttgttaaag ctaatatgat ttttttcata tctcaaatcc tccctcttaa
    12961 tttgttgata cataagttat tttaacatat aatgagagtt tttgaataat atatttaaaa
    13021 tattttataa attttcatta aagtaaagtc tatattaaaa catatctata ttaaattatt
    13081 gttcatattt acatcagtca tagtagaaac cataacagct tttattgtat gcattctatt
    13141 ttcagcttct tcaaatacct ttgaatattt tgaattaaat acctcgtttg taacctctaa
    13201 ttctgataat ccgaactttt cataaatctc ctgagcaacc ttagtttcta aatcatgaaa
    13261 tgctggaaga cagtgtaaaa atataacatt ttcattttca gttttcttta tcatatccat
    13321 atttacttga taatctttaa gttgatttat tcttgcttca tattgctcct cttctcccat
    13381 agaaacccat acatctgtat atataacatc tgcaccttta acatcatcaa tattttcagt
    13441 caacattata tctcctttgg atttcttggc tatttccttc atttccttaa ccaattcttc
    13501 atttggccaa agttccttag gtgctagtgc tacgaaatgt attcccattt tagcacatcc
    13561 tatcatcagt gagttcccca tattatttct agcatcacca acatatacaa atttaacttt
    13621 attcaaatct ttatctacat tttcaattac tgttaaaaaa tctgccagta tttgtgttgg
    13681 atgatattca tctgtaagtc cattccaaac aggtacacca gaatattttg ctagactttc
    13741 aactgtttct tgtttaaagc ctctaaattc tattccatca tagaatcttc ctagaacttt
    13801 tgctgtatct gatacagact cttttttacc catatgacaa tcatttggac ctagataagt
    13861 tacatgtgct ccttcatcat gagctgctac ttcaaatgaa catctagttc ttgttgatgt
    13921 tttctcaaat aataaagcta tattttttcc ttgtagcaaa tcgcctttta taccaacttt
    13981 tttcttagtt tttaaataac ttgataaagt taataaatat ctaatctctt cttttgtaaa
    14041 atcctttaat gtcaaaaaac tcttaccttt taaacttata ttattcatat taattcgccc
    14101 cttcttataa actttttaaa ttcaattaaa cttgttagca ctttactttt ttatttactt
    14161 ctaattttta tctttaatca actatttttt gaatatttag ttaatttcta gtaatatatc
    14221 ttttaggatt tcaagagcct catctatttc cttataactg attgttaatg gtggtaaaaa
    14281 tctcaataca ttttttccag cagtcaaaat aagcaatcct ttttttctag ctttctcttc
    14341 tataatacta gattcaatat tagtttcaat tcctatcatt agaccaatac cttttgtctt
    14401 taatataact ttgttattaa aactttcaat agattttctt atataatttc ctttttctaa
    14461 tacttcatta taaaagccat ctttagatat ctcatctaat acaactgaag ctgccaccat
    14521 agctaataaa ttacctccaa aagttgtacc ttggtctcct tttcctagta cttttgaaag
    14581 ttttttattt accaatactc ctcctactgg tattcctgct cccaaccctt ttgctacggt
    14641 aactatatct ggttttacat caaaatattc atagccaaaa agtttaccag ttcttcctat
    14701 accgcattgg acttcatcaa aaatcactac aatatccttt tcttgacata tttttactat
    14761 ttccaaaaca taatcttttt caagaacatt aactccacct tcgccttgaa tcgcttcaag
    14821 aattattgca caaactgtgg aatcaagatt attttttaaa tcttcaatat tatttctttc
    14881 tatatattta aaaccttcgg gaagaggata aaaatactta tggtatttgt ccataccagt
    14941 tgccattaaa gacatcattg ttctaccatg aaaagagtct tttaaactta tgatagttcc
    15001 tctaccatta ccatatttgt cactactata ctttcttgct attttgaatg ctgtttcatt
    15061 tgcttctgtt ccagaattac aaaaatatac tttagccatt ccacttgaat taattatttt
    15121 ctctcctgaa tacaacactg gctcattaaa atataaattt gaagtatgta ataatttatc
    15181 tacttgctct tttagagcat tctttaaatt actattacta tacccaagag aagatactcc
    15241 atatccactt gtaaaatcta tatatttatt gccattagta tcaaaaaaac aacttccttc
    15301 accataatct atgacaaaat tgggttggtt atatgtatct ataaaatatt cattccattt
    15361 tgaaattgta ttgtcgttat tcattcttat tctcccctct taaacttata attttattca
    15421 gtttcttttc ttattaatgt acctattcca ctatcagtaa atagctctgt tattatagaa
    15481 tgtggaactc ttccatccaa aatatgtacc ctatttactc cgttatttaa ggcatctacg
    15541 catccctcta ttttaggtat catacctcca gtaattatac cttcttcaaa taatttatca
    15601 acatcctcta atataacttc tgttattaat gatttttctt catctggctc tcttaacaaa
    15661 ccagggacat ctgtaagaag tatcaattta tctgcattta actctttagc tatagcagaa
    15721 gctgctgtgt caccatttat attataagtc tctccatcat ctccaacacc tatagttgca
    15781 attactgaaa tataacctga ctttagacaa gattctataa gctcaacatt tacttttttg
    15841 atttctccta caaatccaag ttcataattt ttatatgggt cacataaaat catattatta
    15901 tctattccac aaagccctac tgcttttcca ccttttgtat gtattttatt tactaagtct
    15961 ttattaacct ttccagcaag taccattttt acaatttcca tggtctcttc atctgtatat
    16021 ctaagaccat ttacaaattt actttctata tccacttttg ctagcatctt attgatttct
    16081 gcccctccac catgtactaa aactatattg attccaacat aactcattaa cacaaggtct
    16141 tccataacag attcttttag accatctttt ttcattgcac ttccaccata cttaactaca
    16201 atagtctttc cctgatgttt ttctatatat ggtaaagctt ctataagtgt atttgctttt
    16261 tctatattaa tcattaaagt atatcctcct aatttctata acttccattt attcttacat
    16321 aatcatagct taaatcacat ccccatgcat ttcctctggc attgcccata tttaaatcta
    16381 ctaatatact tatttcgtca tcttcaagga ttttttttgc tttttcctca ttaaaatcta
    16441 atccatttcc atttttacat acttcaatat atcctttcat actctcaaaa ataatatcaa
    16501 ctttttccat atctatttct tcacctgcat aacctaaagc acacagtatt ctaccccaat
    16561 ttgcgtcagc tccaaataca gctgtcttta ctaatgaaga agatataact gtttttgcta
    16621 attttactgc atgttcttca cttaatgctc catttatata gcattcaatt agttttgtac
    16681 atccttctcc atcttttgca acaagtttag caagttctat acagacatat gtaagtgcac
    16741 tcaaaaatac ttgataatgt tcatcttttt tgtttattct atcatttttt gcttttccat
    16801 ttgctagaat cattaccata tcattagtac ttgtatctcc atctacacta actctattaa
    16861 aacttttgtc aacagcaatt tttaaagctt cttttagcaa aactccatca atatttgcat
    16921 ctgtagttat aaatcctaac gttgttgcca tattaggatg tatcatgcca gaaccttttg
    16981 ccatacctcc aatagttatt tttttatctc catacattat tgctactgct atttcttttt
    17041 ttataatatc agttgtcata atagcttctc ttgctccaat atgaccttgt ttacttagat
    17101 tattcactaa ttcatccata ttttcttcta ttaaatctat atttaatggc tttcctataa
    17161 cacctgtaga tgcaaccaaa acatcacttt ctttaatatt taatttatca ctggtgaatt
    17221 tagccatttt ataagcattt ataagtcctt cttttccatt aaaggtatta gcattagcac
    17281 tatttactat gatagcttgt gcttttccat ttttaatgtg ttcctgtgta acataaacag
    17341 gattgccctt tactttattt tgagttacta ctgctgctgc atcacataaa acatctgaat
    17401 aaaccaaagc taaatctctt ttttctttat tttttctcaa gccacagtga atccctgaag
    17461 caaaaaatcc ttctgaaact gtaactccac cctttataat ctccatattt atcctcctaa
    17521 ttatatgagt ttagtatttt ttatttctaa aatgatggtg caatattttt taaacctgta
    17581 ttttcttcaa taccaaatat tatattcatg ttttgtatag cttgacctgc tgctccctta
    17641 atcatattat ctatagctga acagattatc aatgtatctc cattttcatg taatgatatt
    17701 acacatttat ttgagaatct aacattcttt aaagaagcta ccttatctaa tggaagaatt
    17761 tctataaatt ctttaaattc ataataatca gttaatttcc tatgtatatc atttatagaa
    17821 atattatctt cttttgtaca atatatagtt gataagattc ccctatttac tgggattaag
    17881 tttggtgtaa aaactacact tactttttct ttgcaggatt cacttaaatt ttgttctatt
    17941 tctggagtat gtctgtgttt ccctatttta tatgcagtga tattttcatt aacctccgta
    18001 aagtgactac taatcgataa ttctctacca gcacctgtaa gacctgattt agaatcaatt
    18061 attatattat tattttttat caatttagaa cttagtaatg gcatcaatgg taaagaaata
    18121 ctagttggat aacatccagg atttgcaatt atatctgcat cttttatatc ttctttgtat
    18181 atttcactta atccatatac agctttttta tgtaagattt tatctataaa agatactcca
    18241 taccatttac tatatacttc ttcatctttt attctaaagt cagcacctaa atctataact
    18301 ttctttttcg atttaattgc ttttattaca aacttttcac taactccatg tggaagggct
    18361 gtaaatacaa catcacacat atctataact ttttcatttt ctatacatat catgttattt
    18421 ttatatccta tacttggata tatatcaact atatcttttc caacatacga atttgaacct
    18481 atcgctgtca cttcgacttt atcatgattc attaataatc taatcaactc tgccccgaca
    18541 tatccagttg caccaataat accaactttt attttattca ttttgttccc tccattttta
    18601 tattcaaata gtcttaaaat cctatctttc cactttacta tatgataatc atttgataat
    18661 acgtagatta aaatactcta attaaaacaa aaaacccctt agcattataa atactaagag
    18721 gcgattttcc gcggtaccac tcttattggt aaaattacaa taatcattaa aactcaaatt
    18781 aaaaagtatc tacaaaatgt acatttaaaa ttaaaaaagc ctcttggtca aagaccaaga
    18841 gacgaatata cacccgcgtt accactctaa ttgataagat aatcttaccc actctaatct
    18901 cttaaggcga gattcaccaa ttaccatact attacttctg gtaatctcct ccaaagctct
    18961 attcacaata aaattcgtta ctaggcttcc accattccca gctctctatc aactagcttt
    19021 atgctactct ctttttcaca ggatttcaat ttattttctt attgttttat atgatagttt
    19081 atttttttaa ctttgtcaat ataattttta aatttttgga aatattttct atataattaa
    19141 tttccagcat tttgtatcta aattgagtta taaatatcta cagtaatagg acaccatgaa
    19201 tttcctgctg taatatattt taaaaaagtt ctccctcttg aatcaagtca ttcaaaagct
    19261 atacctttgt caaaattatt tttcatccag cgttttttag aaaaaacaca attttctcca
    19321 taaaagagac atacatacaa ctattctttc ctaatgtaat atatgtatga tttctttgtc
    19381 atttaacttt ttcaaaaacg caattaacaa tggaataccg aacaacccaa taaatccaaa
    19441 gaaatgtaat cctgttagca tactggctaa ggccaataca ggatgtaact ccatatgttt
    19501 accaactaat tttggttcaa taatattcct gataatagta atcacaatat atagtagtgc
    19561 aattcctaat gccattgaat aatcccctaa aaataaactg ataatacacc aaggtattag
    19621 aatacttcca gttcctaaaa caggtagtat atctaaaaga gcaatgaata aagcaattat
    19681 tccagcataa gaaatattaa taatagcaaa accgacatat aattcagaaa aagtgatagc
    19741 aaaaattaaa agataagaaa aaccacattt aataatggta tcaatagtaa acgcttttgc
    19801 ttctgctaaa agataacttt tatttttagg tatctgtagc actataaatc tctttatcgt
    19861 tggataatca attgctataa aaatagaagc aacgattgta ataattgttt tcataaatag
    19921 taatggaaca gacgaaacaa tatcagtaat accagatacg atattatttg aaagagaaac
    19981 tatgaaaaca ctcatttcat tcatcaatac aggcatattt gcttctatta attcaataaa
    20041 cgaaaaattg aatgaaccag aaaatagttc gacttctttt ataactgttt cagtcaaagg
    20101 tattaccaat tcctcaaaca tggttggtag gaaatgaaaa atttccttta ttccatatat
    20161 tagatatgta cctattacac ttactattat tcctgcaatt aaaaagaata aaaaaacaga
    20221 tatggttgct acaatacctc gctttattag taatttttca cttatgtata agactggttt
    20281 attcaataaa cttgctatta aaaatgcaaa aacaaaagga agtaatacag aaaacgcata
    20341 tttccctaat aacattagta agcctaatat cactaccaaa taacagaaat ttattaaaaa
    20401 tctctgctta ttttggtatg atgtatgatc ttgttcattc aaataaaatg cacctcctac
    20461 tttatagtaa ctttatatgt gccttttgga gcaacagggg gcattgtttc acacattcca
    20521 gaacaacttt ttgcttgcac aaaatattca atcatatcac ctgactttcc tatcatattg
    20581 gcaaaaaata tttctgcttc tgtagtttct tctaacataa tactttccca tgtttgaaaa
    20641 ccatagtatc gataaaacag tctacaattt tcataatcta agccagcttt actataatca
    20701 actatttgaa tagtaacttc taaagcatca ttctctgaaa cgatttcttc taatcttttc
    20761 acggaaatat agagcatatt ctcatcccaa attgctcttg tcctgcaatg aataacatct
    20821 tcatttcccc agccagttct cacatatcct gtacgatttt ttataatatc tggctctttt
    20881 tcaaaatcaa actcatatcc tttaatttca tatccaggca aagcgttctg ccattgtttt
    20941 attgcaattt tatcctgttc aattccatac attggaacat agacacgact atttaaaatc
    21001 acagaattaa cataagcagt aagttcatca ctgtcctttt gaaacggaac aatatctata
    21061 cgaaagattt tgaatggacg tccatatctg gtttctacct tttttacttc ttctaaaatt
    21121 ttttcatatc tttcatacaa atagtgttct tttggcgttc tgctcacaag taatgtttct
    21181 tcatcaatta tttttaaata acagtcaata tgttgtaaac cataatcagc aaaattagaa
    21241 aatatataat actcattcat tccagtatct cttgccacca tagaaaaaaa ttcttcgtca
    21301 gaaattcctt tcgcacgatt ttctgtctgt aaaatgtgca tagacatcaa tttattgaaa
    21361 ccatctgaca taagatttcc gcctgttagt gcataaggta atttcataaa tggcaaacca
    21421 atctgtttcg caatcaactc ttgtgattga tcttcttttt gttcataaga gttagtagtt
    21481 aataggttat gttcgcaatc aaacatgatt tctggtttat ttatggatac aaatggtgtt
    21541 gacatcttat attctgcacc agccaaaaag agttttccgt tttcatcaaa aatagggtgc
    21601 ataccccaat cacgaaccca tggtgtatca aatccctgtg gagcaatgca gaaaatcaaa
    21661 ttttttaaat ttccacccca cttacttaaa taatattttg caatttcaat ttcctcttta
    21721 tttggtacac acatgtatac agaataattt tgcgttaaat ctacaatata cttatgggga
    21781 agaaaagggg gccatgcaag catgacacct ttaatcggtt cccattcccc agctaaacgt
    21841 cttttcattt ctaatacctc actttcttac tttttccaca aatgaaatgg aatttctcta
    21901 attttaagat ttttcaacaa tgtttcaaat tcattttttt gaaaggtttt ctgattacat
    21961 aaaacttcca tttctagtcc cttatactcc atgagatatt ctgtttcata aaacccattc
    22021 tgaagataaa attgcttcct taaaattctt tgctgtaaat taggagcact gtcctctata
    22081 gtttccatat caagaacaat ttgacaattg ggatattgtt ttttcataag tgacagtgct
    22141 tttccaccat atcctttaga gcgttgttct ggagaaattg caagaaataa tatatatcct
    22201 atatgatttt caatcaccaa aacataaaaa ccaataaatt gttgcttatc atataaagca
    22261 gatacttcta tttttttact ttgaactaaa ttaagcattt cttgtataga catacgttct
    22321 tcatctggaa atgcctcgtt attaagttct tcaaattttt ctaaatcttt aaaatatgaa
    22381 gttacttttt gtattgttaa gctcatatag atacctccaa attgatttaa taatgatatt
    22441 ttttctgttt ttttattata aagaaagccg tcataatagt tgccaatatt tcagcaccaa
    22501 caatagaaaa ccatatccca tttactcccc agaatatagg gaatataagt actgatacaa
    22561 cttgaaatac taaaatacgc ataaaagcaa taagcgcaga agttaaaccg tcatttaatg
    22621 cagtaaagaa actagaacca aaaacaccaa aaccagaaaa taaaaaggaa aaagagtaaa
    22681 tcataaatgc tcttaatgtc atttccatta aattattatc gtaacccaca aaaataaaag
    22741 caatcggttt tgataaaaat tcgcctatta taaacataaa tacagcaaaa caaataatta
    22801 caatcaaact tctttttctt aaatttttta attcgtcata attttttgct ccataatgat
    22861 aactgattat aggggcagta ccaacagaat acccaataaa aacagcttga aatagtaacg
    22921 ctacataaag aagaacacca taggatgcaa cgccatcttc gccagcatat tttagtaatt
    22981 gagcattata cagcatactc acaacagatg tggaaacatt agtcattagt tctgaagaac
    23041 catttgcaac agtctttttc aaaacatcac aatcaaattt aggtttctta aatttaagca
    23101 aactgttgtt ttgtcggcta aaataaagta atggaatgat accaccaaca tattgaccga
    23161 ttgcagttgc cagtgctgca cctaccaatc cccatttaaa aacagtgata aataatgcgt
    23221 ctaaaacaat atttgtaatt ccagccataa ttgcaacata taatccaagt tttggctttt
    23281 ctgctgttgc aaataaacac tgaaattcgc actgcaaaat ataggcagga atagcgataa
    23341 ttaccacaca tccataaaga atactatctg tcaataattg accatctgct cccatagcag
    23401 aagcaatcca tggcatagtt actataccta aaacagctag aataatacca caaccagcag
    23461 aagtaacaat gagtaacgaa aactgttcgt ttgcttcttc tttttttcct tcacccattg
    23521 ttttagcaat taaagctcca ccacctgttc caaaaagaaa gccaacacac cctaagatta
    23581 gcaaaaatgg cataataaaa ttgacagcag taaaagcagt tttccctaca aaatttgaaa
    23641 caaaatatcc atcaacaacc ccataaatag aacttattac cagcataata attgtaggaa
    23701 atgtaaattt taataagcgt ttataattaa aattatctga caactgtatc attgttcata
    23761 cctcctaaac caatactctg aaaagttagc aattgcataa gaaagatgtt ttatattcca
    23821 ttcagatgta ttaactataa tatgatagga agtttgattt ccccataagg agctcgtaaa
    23881 aaattctctt gatcttgctc gatttttatc aatctctctt atctttcttt ctaattcttt
    23941 ttttgaaata tgttcattgt ttaacttttt ttcaatacag cgttgtattt taaagttcat
    24001 atttgcacaa acaaaaacgt taaatggctg gtacttcttt aataatatat ctgcatttct
    24061 accaacaata acacaatcct tacctgtact ggcaatctga ttgataacat ttgattgttc
    24121 tattaacaaa tctgtcttca tggattgcat agacaaaata ttagtaaaag aagtacacat
    24181 tgttaaagga acgtttctcc aaccatgatt ttctaatatg taggaaacat agttttcgtc
    24241 aatttttttc tttctagcta tagcagtgat aatttcttta tcgtagtagt caaaatttaa
    24301 aatatcagca agttgttttc caagttctcg tccaccactt ccaaactctc ggctaattgt
    24361 aataattttc ataatatctt ttcctcacat ttcattgaat ataaaagctt tctatgttat
    24421 cctaaagtat ctggtaaccc taaagtcaat aggagattta aaaatgatta aaaaattata
    24481 taagacaagt gaatttgcag aattgtgtgg ggtaaaaaaa catacacttt accattatga
    24541 tgaaattgaa ttattaaaac cgagtattac ccatgaaaat ggctatcggt attatacaat
    24601 tgaccaattt gaaaaattta atattatttc tgtgctaaaa aaagcaggta cacctttaga
    24661 agaaataaaa caatatctca atgatttaga tacgaatacc tttcttaatg tacttcacag
    24721 aaagctaatg gatcttcaag aagaagtgaa gaagattgaa aaaatgtgtt ctatgttgag
    24781 aaatgtcatt tcaacaatgg aaatacatct caatgtaaac acagaaaaaa tcgaaattgt
    24841 aaattgtgag gaagaatatc tgattgcaac taaaattcct gaagctgtac taacagatga
    24901 aaaaacaatg ttacaaggta ttggaaatca cttacaatat tgtttattac atgattataa
    24961 ttttcatgta ggagaaattg ttcttgaaaa aaatataaaa cagggaattt ttagagagag
    25021 ctattattat agccttatta aaaataaagt agatgatgag cgccttttta ttaaaccaaa
    25081 gggaaattat gcagttatgt atcaccaggg gagttatgac agtttatata aaacttatca
    25141 aaatatgaaa aatcagttag aagaacaagg gtatcatatt gttggaaata tttatgaaga
    25201 agatttaatt gattatttat cagaacataa cgccgaaaac tacattcaaa aaatttctat
    25261 acaggttatt tgaaaatata aaaagcgtgt atatctcaaa tcacatgaga aatacacgcc
    25321 ttttttaata tctcgtattg tctataataa tttgcttaaa atgtcctttt ttatcttcta
    25381 aagttggtat cttatttcca aatttttgta gaaattcagg ttcattgcta ttatttgttt
    25441 cctcaatgca aactgcattt cctcatgaat ttcagataca gaaatagcct tttattttcg
    25501 ttaaccattt aatcagtttt ttactatctt tttataaaat cttaacatgg aggctttatg
    25561 cctccatttc ttttgtagtt gtcttaaaag tagtgcaaat ttttttctta aatatatatt
    25621 atataaatta ttcatttata tagagtatta tattatgctc tgtaaatagt tacaatattt
    25681 aaaagaatga aaggagaaca aaaactatgg aaattgatta taaagcaatc ggacagcgaa
    25741 ttaaaattgc aagaattaaa aaaggtataa cacaagaatc cgttgcaaac attatcaaca
    25801 tgacaccatc ccatatgagc aacgtggaaa caggaaaaac gaaagtcagc ctgccaacct
    25861 tgattgcgat tgccaatgca ctttctgtat cagtcgatac tctcttatgt gataatgtac
    25921 tttcttccaa agtaattttt gaaaaggaag ccaaagatat tttctcagat tgtgatgaat
    25981 atgaaatccg ttctttagtt gaactgctaa aatcagcaaa aactgtaatc cgtaaagaca
    26041 gagaaatccg caaacaattt gaaaaataaa accacagctt caaggtataa attgatatgt
    26101 gttgttagct aaggtctttt ctttttttat ataatcattt ttatataatc aaataaccta
    26161 tccaataatt ttccaattac tgtccttatg aaatatcaat ttatactatg atacctgtgt
    26221 cgcttttgtc tgattatcaa ggaattttac agctaccttt tcattatcaa cgacaacagt
    26281 aaaaataggg tttaccaatt cagaaagtaa atattcttga aatatactat tttcctttca
    26341 taaaaatgat aaaattttat tttacatccc acgtaatgaa gtgttcaata aataagttaa
    26401 aataatttat ttacctcctt aatcatattt tttatgaata cctaataaca cagtatcaat
    26461 agaatcgact agacctttta tagcttcttc tttactcaaa agtgatttcc caagttgcaa
    26521 agtcgaataa ccatgaagta cactcattat taagtttaat acttcacctg tattctttgt
    26581 atttagatta caagaaagaa taagtttttc taataaggat ttatattcat caaagatttc
    26641 taatgtttca ttatttccat gccaagtagc ccactgaatt gtttcataaa caccaggatt
    26701 agaaattata aaattaaagt atgctatact tatacacttt atagctgtat ctccaaaatt
    26761 tccaatagcc gcctttatca tttgactatt catctctctc attcctttat gagctacttc
    26821 aagtaataaa tcatctagac tttctatatg attgtacaaa gatggtgtac gtattcctag
    26881 cttttctgca ataactttta aagaaacttt gttaagccca tctttattaa ctatatctga
    26941 tgtagcttgt ataactattt ctctactaac acgcatgatt ttccctcttt catttaaaat
    27001 taattacttt attagtttag ctaatctaat tagtttcgtc aattattgta atttataaaa
    27061 ttctttatac tattataaaa tcttgacagt ttaattataa tttaatataa tactaattga
    27121 attagtttta atactaatat aattagtatt atattaaatt ctatattaca acattatttt
    27181 atagtttgat taatttaaca atcactaata tatcaaactg aaaggagatt tttatggaaa
    27241 aaaaatattt cgaaattcat ggagttcctt caatcctttg gggaaatcct tcaagtaaat
    27301 tatatattta catacatgga caatgtggca ataaagagga ggctgaagct tttgctaata
    27361 ttgcagttcc acatgagtgt caagttttaa gtgttgattt gcctgaacat ggagaacgta
    27421 aaagagaaaa aaattcattt aacccatggc atgttgttcc agaattagta tctattatgg
    27481 aatatgcaaa gtgccactgg aatcaaattt cgttatatgc aaatagcatt ggagcatggt
    27541 ttagtatgtt aagctttgaa aaagagaact taagagagtg tatttttgta tctccaattc
    27601 tagatatgca acagctcatt tcaaatatga tgctttgggc aaatgtatca gaagaacagc
    27661 ttaaacatga actaattatc ccaacttcat ttgggcatac tctttcatgg gaatatctac
    27721 aatatgtaaa acaacatcct atcactcaat ggaatgtacc aacaaaaata ttatatggta
    27781 aacatgatga acttactgaa atcggtgttg tagagaaatt tgtagaaaag tttaattgca
    27841 accttactat tatagaaaat ggcaaacatt ggtttaacac accacaagaa ttaaattcat
    27901 tatatgaatg gttaaatact ttagttaaat aaaaaataat tatattatta atatgattaa
    27961 attatttata aatgttattt aattaatttt attttagcat tattaaaata actacataaa
    28021 gaataaatta gttattatta aagaaattaa aagtatatag agtattaata attttttaat
    28081 aattagttat tatagaaaaa agagggatat aatattgtct ccctctcttt cttctgtaat
    28141 attatataat ttttatttat cactctcaat aaattatagt tatctacaaa attcaatctt
    28201 taatacacta ttaatatatt gtgatattaa tattacagta ttaaataaaa tctaataaaa
    28261 ttaactataa aatatctatt atataaatat ccactcttat gtttgaaatc cgtcatatag
    28321 ttttatcctt cttatctttt atatcaataa ctttttttaa taaaattgac aaaactaaag
    28381 taaaaaacct tattgataat gaaacaaatg atactataag ttctgatatt atagtaattg
    28441 catataaata gacatcataa aaataatata atattgtcac tataaaatta aatgtaaaaa
    28501 tctcaaatct aactaaatac acatataggt attttttaag tttttaggta tttcttctga
    28561 aaatgattta ttgattgata ccaatttaca taatcttttt aatataaaca atgatacaat
    28621 atatgggaca gcacatatgt atatagctac ttatattaca tattacagtt ggcatattcg
    28681 tatttgtaat gcttatacca attttaaaat acaccatcag tactaatggt attaaaataa
    28741 tctataataa agttaaaatt attccaatta gtacaatatt atttaatatt ttacaactca
    28801 tattcttttt tatataaatt taccacctta tacattctta tttttagtgt atattacaat
    28861 ggttttatat attatatcaa taatttatta ttgaaattca ataaattgta tattataatc
    28921 aataatatac tttatataaa ggagatgata ttttatgatt acaaaatttt ttagtaatat
    28981 attatcagta tttctatatt ttctattatc acttttagga gttgctggta taatattctt
    29041 atgtatgata cctatgtttt tatatgattt tagttctgac aaagtaatcg ctttaattgc
    29101 aagaatacta tatttttctg actactttat agtcatctta ttcttgatat ttataattaa
    29161 tagtactaag tattccccat tcgtacttga aaatgtaaaa aggtttaagg taatgggatt
    29221 ttgtttattg ataaacacta taattgaatg tatcaatggt tataatttaa atactaataa
    29281 tataagaatt tttggaactg atagtggcgg tatctcacca cttatgatta tctcttttat
    29341 atttgcacta atgtgctttg taattgcaga aacatttgat aaagctataa aaataaaaga
    29401 agataatgat ttaacgatat agaggtgatg ttatggcaat agtagttaac ctagatgtaa
    29461 tgatggcaaa aaggaaaata tcacttaaag atttggcaga aaaaatagat attacaaatg
    29521 caaatttatc aattttaaaa actggaaaag caaaagctat tagatttacc actctaaacg
    29581 aaatttgcaa agctttagac tgtcagccag gtgatatact tgaatatgta gaagatgaaa
    29641 atgattaaaa aagagtgttt agaaacactc ttttttatta tactatatga tttttattct
    29701 tttactatat tattgacatt aatattaact ttgtttaaag tcataacaaa atatgttcta
    29761 agaaagaaac tgttccttta tctatttgtt atccattacc tataagaact gtatcacact
    29821 aaataatact tttaaattga taattttacc acagattcct atatacattc ttttctacct
    29881 aatatttatt taaactgtta gcaaaacatg gaactttttc atttacttat acctccattt
    29941 atattattgc atagtttata gctacgtgtt ataaattaca ttattgatga ttttatctaa
    30001 catttgtaat cttttagata ctctttgaag ttacaacact gttatactct aattaagtaa
    30061 actaaatctg atacaagttg gtgattatat gaaaagaaaa ctttcaacct attttaaagg
    30121 atatatttta ggtttatgta tagcattttt attatttact tttatattaa aaaaattaat
    30181 tatagaaaat atcattggaa taataattgg aactggaatt gcatttttac tgatttacct
    30241 atttaataaa aaaagaaaat aatattctat aaaaaggtct tttagtgaat ttacaaaaaa
    30301 ttaataagaa taatatatac ttagtattta aaaagggtaa caactctctc tagctgttac
    30361 ctcatatatt tatctatatc tttagtatta agttttttaa tttctacttt tttaattatc
    30421 aatttctgta tgtagatatg ctaaaccttc caacttgaga tttaaataac ttttcaatct
    30481 cataaactat tctatacacc ttattttcgt actctaaatc ataatacaca tttatttcac
    30541 ctatactgtt tacacttatt gtataatgtt ctttttctat tatacatatg cttccaaaat
    30601 ctgacaggtc attatctatc aattttaact gtttttttat ttttgaaaaa tctaatcttg
    30661 gaaatatgtc attaggataa aaacttttat tatatacaag catttcatcc accccttatc
    30721 attctattta caccatttta taccctaatt aataatgtac taatcaagtt tttccatatt
    30781 cttcaaatta ctttatataa aacaaaatac aaatttattt tttaatgctt taaattataa
    30841 tttttaaatg tatattagta aaatataagt atattttcat ccacaacaat aaaaaaataa
    30901 tagctatata aaaatagcta ctatcttttt attaattaat attcatttgt tttattatta
    30961 cgacttatat tatagtttta tatattttac tgatgtctat aatatttcag acatttttta
    31021 tatttattct actgctataa tttaattaag taaattaaat ctaattttac aaatatatcg
    31081 ttagaacaaa aactcttata atatactaac atattatcta tgccttatca ttcattctgt
    31141 ttataaagct ttatatcttg ttaaagtaat accctacttc tcttatcgtt ataatttttt
    31201 gaggattttt ataatctttc tctattttct ttcttaatcc actcacagca accactacac
    31261 tataattatc atctaaatac tcattcatcc atacatgttc atatatctcc ttaatagtta
    31321 gagtcttttc agcattctct ataaagtaat ttaataatct attttctgtt ggagttaact
    31381 ttatca
//
LOCUS       DAFAZV010000049        31151 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFAZV010000049 DAFAZV010000000
VERSION     DAFAZV010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 31151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31151
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.049"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..1465
                     /locus_tag="KOU88_003091"
     CDS             <1..1465
                     /locus_tag="KOU88_003091"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="chromosome condensation regulator"
                     /protein_id="HBK3212947.1"
                     /translation="SDKIVFNKKNEKLVMFNDKYIKTNNKYINYKNIFKDNFKYTSII
                     LPFEVSDIDISKTHSLAVAKDGKLYGIGSNSYKEINQTLEDIELLTLTEVNISDVKKV
                     ACGDNYSYIIKTDNTLWSYGKNTEYQLGVGHNNDVRELQKVTGLPSVKDISIYNSMTL
                     VLTNEGELYAQGYNTNGLFGLGESEKDKIIRTFTKVLTNVKEIKSHNDDHILVIKNDN
                     SLWITGKNKSMYKISISITDLYEFTKIPIPEHLNDILDIELSDDTIYMITKVDTSKAS
                     IEIVEKSISQVRVVVQDPNNVIEKLEMFINDELISTKTNLEINSIIFEIPQNKIVLGE
                     NKILIKASSPTGDLYSSMFIFKSETGLKVKKDSILMINNKVYSIINITENNTDLIVTL
                     NEGLKDDMMENNPIYQLINKTKVQVKINKSDLFKDMKLVEIKKSDSSYQEIYELEEAN
                     IKSAQPKIIVEKGDKWTAIKRPSMIFRYDAENNEPQA"
     gene            1482..1835
                     /locus_tag="KOU88_003092"
     CDS             1482..1835
                     /locus_tag="KOU88_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212948.1"
                     /translation="MFKFDKNKIEQIKQGRKVEMQYKDISDISIGQVKQDDDITNNFI
                     ANAEIYEMLLNQSSVNEASNISTFSVRKSGGESGMVEVYVALILRGKKTIEEVPAVIR
                     EQVRIRCKELEIPVE"
     gene            2098..2358
                     /locus_tag="KOU88_003093"
     CDS             2098..2358
                     /locus_tag="KOU88_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212949.1"
                     /translation="MDKLITELSSLGAIGILCALLFKNTMQEKKEDRDMYKKTVENFI
                     ELSTQQQEINKNILVQMGIMKTDVEEIKEDVTGIKGMLQNGV"
     gene            complement(2566..3021)
                     /locus_tag="KOU88_003094"
     CDS             complement(2566..3021)
                     /locus_tag="KOU88_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212950.1"
                     /translation="MGLRDKFAQSFARSKTMSGPEKKANEIMGKLLLKKAILPIVLMF
                     VIIIAGAMLKINSWVTLGINLVIAVGAFFYIRNSSKKYQNFKPYVGNLISLEKKGKKE
                     YVAIIKQGKLPVKLQIAYGGEDLEHVKKNQMVQISYNPDAKIAILVNRQ"
     gene            complement(3249..3668)
                     /locus_tag="KOU88_003095"
     CDS             complement(3249..3668)
                     /locus_tag="KOU88_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212951.1"
                     /translation="MDTLGERIVYLRKSKNLKQYELEEMLGCDNLSKFERNIRKPNYE
                     ILKSIAEIFNVSVDWLLNGDNLSHKSDLICDSSSNYPFNSINSNEIKLLNNFRKLNDY
                     DKAKIEGMIELKLHEYEKEKDLGKIEYNKNKDEKIDK"
     gene            3967..4176
                     /locus_tag="KOU88_003096"
     CDS             3967..4176
                     /locus_tag="KOU88_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212952.1"
                     /translation="MDARKKWIPFLGVQVKQRLIELNMTQRELAKKIGVNENYLSAIL
                     NGRRTGKKYKSSIYQLLNIEYSEDD"
     gene            4208..4417
                     /locus_tag="KOU88_003097"
     CDS             4208..4417
                     /locus_tag="KOU88_003097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212953.1"
                     /translation="MCKLDSDGVIECCRAIDDFITALSNIKSLNMERLNTLTKYSSTC
                     SILLKEGNYEGCTIVYRKMLEELKT"
     gene            complement(4634..5032)
                     /locus_tag="KOU88_003098"
     CDS             complement(4634..5032)
                     /locus_tag="KOU88_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3212954.1"
                     /translation="MDTLGKRIAYLRNSKKLTQRKLMDILKFENLGKYETGDRKPNCD
                     ILMSIADYFNVTTDWLLYGKEKVNVNSSVKEDKEDYLHVTNDEMTILNLYRQLNERDK
                     IKIEGILELKISEYKDLKKHSSNNNEDKMV"
     gene            complement(5453..7945)
                     /locus_tag="KOU88_003099"
     CDS             complement(5453..7945)
                     /locus_tag="KOU88_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3212955.1"
                     /translation="MNHNTSIKNKDSNPKIFLVLTLYLLGIFMGAIDTGIVSPARTII
                     QNSLGVNEKTGIWMITIYTLTYASVIPISGKLADKIGRKYVYLVSIFLFGSGSLICGL
                     SSLFSNFYILLIGRVIQAIGGGGIMPIATAEFGTTFPENKRGMALGLVGATYGIANIL
                     GSSIGSTILSIFGTQNWKWLFFVNLPICLIILIGGVFCIKNNKSESKEKIDKLGTLML
                     ICIIVSLLYGLMNIDFFNFKNSIQDISVYPYLLTFIVLIPIFIFIENRAKDPILSFEY
                     FLNPRILIVLILSLIVGIGMMGMVFVPQYAENALKINAGSGGYFVAILGLFAGIAAPL
                     SGRLIDKFGAKKILLLGFSVSMIGSLYLVLIALKTNTVFSVCVSLIFMGLGMGFTMGT
                     PLNYMMLSNTRLEESNSALATLSLIRSIGTSISPAIMIGFIAHAGLSVQDNIMDLVGK
                     PSTPKIVQLEELENMIDDLKSDPEMAKNLKNVSIPNMNDTSNINMDMTGGKLPKSLLN
                     KVQSADTTNITNITKEISTTMFDEKVPSIITKIQKNVQKGIDGTQSGINGIEDGENKL
                     NSGIKGVQTGIDNMVKARAGINQGIDGVKKGIAGVDKGIKGMEQGLEKQDEAIKELTT
                     AYNKIPTTEKTPTDNENNSNEQNQSNTSNSESDDTKNDSTENKNNNSSENKPNVNEQK
                     ESLNAQIQQLKKTRDDLNTKLQKNKTQKNELSKKLRSMESQKKELQSKLNNSISQKKD
                     MEKSLDTMQQQKKSLQAVLAKTQEVKTEIPKAFDKSKLDYINSIENNRTKIENTLQST
                     LNSGFKQMYITVFCVNLLAFIILLFYKENKTR"
     gene            complement(7959..8501)
                     /locus_tag="KOU88_003100"
     CDS             complement(7959..8501)
                     /locus_tag="KOU88_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3212956.1"
                     /translation="MPKILENVKEDILKVSRDMILEEDYSNISIRKIAQRCGISAGTV
                     YNYFNSKQEIIEYITKSEWDLLIRRIEYSNKNTEDYIKKLNIIFTEIRNFINKVHNIQ
                     YNDFLNTFETERFFEMKKHKDDFHEQLSNKVYEALEKESFFNNDKLVCNIIIKMFFSY
                     STYLHIEFEDLKPYIEKLIH"
     gene            8745..10259
                     /gene="glpK"
                     /locus_tag="KOU88_003101"
     CDS             8745..10259
                     /gene="glpK"
                     /locus_tag="KOU88_003101"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBK3212957.1"
                     /translation="MEKKYVMALDQGTTSSRAILFNKKGEIVKIAQKEFNQIYPKAGW
                     VEHDPMEIWGSQSGVMREVIETAGIRPEEIASIGITNQRETTVVWSRYTGKPIYNAIV
                     WQCRRTSEICDELKNKGLEESIKEKTGLLIDAYFSATKVKWILDNVEGAREKAEQGEL
                     LFGTIDTWLIWNLTRGKVHVTDYSNASRTMMYNINDLEWDEDILRELDIPISMLPLVK
                     PSSYVYGHTDERMLSGAKIPIAGCAGDQQAALFGQNCVEEGTAKNTYGTGCFLLMNTG
                     SNIVKSKHGLLTTIAWGVDGKVTYALEGSIFIGGASVQWLRDELKIIESAKDSEMYAN
                     RVDDTNGVYVVPAFTGLGAPYWDMYARGSILGLTRGAKKEHIVRATLESIAYQTKDVL
                     EAMQNDSKLKLKSLKVDGGASNNNFLMQFQSDILNVDIDRPKIVETTALGAAYLAGLS
                     VGFYIGRNEITSKWSVEKEFNPNMSEEKRCKLYKGWKKAVSRALSWEKEDELDI"
     gene            complement(10373..11002)
                     /locus_tag="KOU88_003102"
     CDS             complement(10373..11002)
                     /locus_tag="KOU88_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3212958.1"
                     /translation="MDKNYTMPIYQKIALDIANKIYTGEIQEDSVLFGRSVLAGKYNV
                     SPETIRRAVKILEDIGVVKSIKGKGVIVLSPDKASSFIKKYRDITNISSYKSTLYNLI
                     DTKSNLENEILDTINKILDYSNRLEIINPLVPVQFTINSNCKYIGQTAAQTKFWQNTG
                     ATIVAIKRGEELIISPGPYIEFLEGDILLVVGDQHIYNSIPMFLYENEK"
     gene            11590..12381
                     /locus_tag="KOU88_003103"
     CDS             11590..12381
                     /locus_tag="KOU88_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LamB/YcsF family protein"
                     /protein_id="HBK3212959.1"
                     /translation="MYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPS
                     HMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALTAFASSN
                     GCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLR
                     FANEVFADRAYDNNGFLVPRNVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKA
                     DSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV"
     gene            12410..13630
                     /locus_tag="KOU88_003104"
     CDS             12410..13630
                     /locus_tag="KOU88_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HBK3212960.1"
                     /translation="MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQ
                     DFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGG
                     LAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGM
                     IIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDG
                     GITGEENIKEITKSSLLGILVATMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAG
                     AIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAF
                     IGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAY
                     TGITSLSSLGALFA"
     gene            13650..14345
                     /gene="pxpB"
                     /locus_tag="KOU88_003105"
     CDS             13650..14345
                     /gene="pxpB"
                     /locus_tag="KOU88_003105"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBK3212961.1"
                     /translation="METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGI
                     VTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFG
                     IDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTK
                     IYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITL
                     DEFIEIEKNNLSI"
     gene            14375..15361
                     /locus_tag="KOU88_003106"
     CDS             14375..15361
                     /locus_tag="KOU88_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase"
                     /protein_id="HBK3212962.1"
                     /translation="MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNIL
                     VGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLS
                     FRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRAKIGGFEGRALKKGDYINTFIQEKDF
                     TINKKLSSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLD
                     GESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLA
                     QAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV"
     gene            complement(15580..16146)
                     /locus_tag="KOU88_003107"
     CDS             complement(15580..16146)
                     /locus_tag="KOU88_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3212963.1"
                     /translation="MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLS
                     SLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPS
                     ILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVP
                     HKIINPSKDTIARGYGVISPPIWPIKSK"
     gene            16498..17565
                     /locus_tag="KOU88_003108"
     CDS             16498..17565
                     /locus_tag="KOU88_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide epimerase"
                     /protein_id="HBK3212964.1"
                     /translation="MKITDIKFEKLRIKLKKPVVVSFGVIEYGESVILKIETDEGYCG
                     FGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAI
                     DIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKL
                     KAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQAL
                     PHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIK
                     INNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEELEGISGGF
                     VMDGDIMNLVNKPGLGIEVNL"
     gene            17584..18744
                     /locus_tag="KOU88_003109"
     CDS             17584..18744
                     /locus_tag="KOU88_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF819 family protein"
                     /protein_id="HBK3212965.1"
                     /translation="MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMG
                     IILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTV
                     SIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADY
                     VIGVPTLIFMFALPAILKNSKKFKKLWPYHVEESELEDCQNEEFMESKEWSIKDIAWM
                     LAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVA
                     LFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVG
                     AIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL"
     gene            18757..20853
                     /locus_tag="KOU88_003110"
     CDS             18757..20853
                     /locus_tag="KOU88_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HBK3212966.1"
                     /translation="MIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEE
                     NTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFP
                     LDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMI
                     DMKDGIKLSTDVYLPDFVDSAKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVR
                     GRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKH
                     LKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRP
                     IENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMG
                     TTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKY
                     LKGIENNIDTTAPVEYYSVGSNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLV
                     FDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEF
                     TVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEE
                     GEIYKFTVITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTTEGYNSIEYIEAKNTIY
                     HGGKYPSKLILPIENK"
     gene            complement(21012..21356)
                     /locus_tag="KOU88_003111"
     CDS             complement(21012..21356)
                     /locus_tag="KOU88_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBK3212967.1"
                     /translation="MEIKRYEGTGRMSRTVVHNNTVYLCGQTHAEGGVIEQTTEVLAK
                     IEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREH
                     LLVEMSVVAATK"
     gene            21648..22538
                     /locus_tag="KOU88_003112"
     CDS             21648..22538
                     /locus_tag="KOU88_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBK3212968.1"
                     /translation="MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFF
                     RNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANM
                     LNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGA
                     VFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGV
                     FASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSA
                     AFYMFLYNKKLDKLDKEKKK"
     gene            22756..24042
                     /locus_tag="KOU88_003113"
     CDS             22756..24042
                     /locus_tag="KOU88_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK3212969.1"
                     /translation="MEKVKVAVIGAGNRGTYAYAPYIYENSDVCEIVAVAEPKKGRRE
                     LFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKP
                     MSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNEN
                     IGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNN
                     QNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYG
                     RCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNE
                     IRIKEFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHV
                     MAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF"
     gene            complement(24131..24574)
                     /locus_tag="KOU88_003114"
     CDS             complement(24131..24574)
                     /locus_tag="KOU88_003114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory YrvL family protein"
                     /protein_id="HBK3212970.1"
                     /translation="MIKISNKRRIPLGEFISVFLFFAVFFGITFCIFTVIGIGFLSFL
                     GFEYKSLGAVLIFFLIYFCITTPIDFLCTTILDIFRYVNKLPYSIYKLCEFIIDFILT
                     FLAMNIIDTFMDSVTIPLSTEILFALLSYLLSECMDFFDRDKKKP"
     gene            complement(24598..25392)
                     /locus_tag="KOU88_003115"
     CDS             complement(24598..25392)
                     /locus_tag="KOU88_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M55 family metallopeptidase"
                     /protein_id="HBK3212971.1"
                     /translation="MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACD
                     GATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFT
                     GYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLC
                     ESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKIEKGVKKALSGDLSRHLIKLPDKF
                     KIEIKFREHYKAFKASFYPNMKKIDSQTVLFETEDYYEFLRMLLFI"
     gene            complement(25958..26434)
                     /locus_tag="KOU88_003116"
     CDS             complement(25958..26434)
                     /locus_tag="KOU88_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBK3212972.1"
                     /translation="MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFW
                     WADGFDDPELRSILETPKPYKSGPDVIGIFATRSPIRPNPIALTAVQIINIDHENGII
                     KIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF"
     gene            complement(26535..27704)
                     /locus_tag="KOU88_003117"
     CDS             complement(26535..27704)
                     /locus_tag="KOU88_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3212973.1"
                     /translation="MLNIKTLCHEINDWVINIRRDLHKTPELGLEEFQTKKKIIKYLN
                     EIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSTNIGKMHAC
                     GHDAHTAILLGTCNILFKLKDYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYI
                     FGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITA
                     LQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIRE
                     ICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAE
                     DFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF"
     gene            27867..28730
                     /locus_tag="KOU88_003118"
     CDS             27867..28730
                     /locus_tag="KOU88_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBK3212974.1"
                     /translation="MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYL
                     AGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDIT
                     GLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDELYLENPKEEKIYTVC
                     EGKAEGIIMGGNLSLIIATMGTKYEIDTKDKILFIEEIGEPQYKLDRMLTQLYSSGKL
                     EECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCEL
                     DATEKIVKLKK"
     gene            28801..29394
                     /locus_tag="KOU88_003119"
     CDS             28801..29394
                     /locus_tag="KOU88_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3867 domain-containing protein"
                     /protein_id="HBK3212975.1"
                     /translation="MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAE
                     FSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNT
                     SSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDR
                     KINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY"
     gene            complement(29645..30280)
                     /locus_tag="KOU88_003120"
     CDS             complement(29645..30280)
                     /locus_tag="KOU88_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK3212976.1"
                     /translation="MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFAR
                     QGALYSPRVESLIKPIEMFTKKISNKLNKVIAFTDSHTPKSIELLSYPVHCLENDVES
                     ELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSY
                     FNQHNIEKNIVVPMNLVDTYDIPNVHPAEILNLVFFNSMIQNGVNVLKEIR"
     gene            complement(30360..31091)
                     /locus_tag="KOU88_003121"
     CDS             complement(30360..31091)
                     /locus_tag="KOU88_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBK3212977.1"
                     /translation="MNIYAHRGFSGKYPENTILAFKKCLDMDIYGIELDVHRTKDGKI
                     VVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQSNKECKIPTLEEVLILISPTD
                     LILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSIKTGL
                     LCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCL
                     KLNVDGIFTNYPDIASNLLHSKQYS"
BASE COUNT        11781 a         3722 c         4949 g        10699 t
ORIGIN      
        1 atcagataaa atagttttta ataagaaaaa tgaaaagcta gtaatgttta atgataagta
       61 tataaaaaca aataataagt atataaatta taaaaacata tttaaagata attttaagta
      121 tacttcaata atattgccat ttgaggtatc tgatattgat atatcaaaaa cacattcatt
      181 ggctgttgct aaggatggca agttatatgg aataggaagt aattcatata aagaaattaa
      241 tcaaaccctt gaagatatag aattattaac tcttactgaa gtaaatatat cagatgtcaa
      301 aaaagttgct tgtggagata actactccta tattattaag acagataata ctctatggtc
      361 atatggaaag aatactgagt accaattggg agttggccac aataatgatg taagagagtt
      421 acaaaaggtt actggattac cttctgttaa agatataagt atatataact caatgacact
      481 tgttttaact aatgagggag agttgtacgc tcaagggtac aatacaaatg gattatttgg
      541 actaggagaa agtgaaaaag ataagataat aagaactttt actaaagtat taactaatgt
      601 taaagaaatt aagtcacata atgatgacca catactagta attaaaaatg ataatagtct
      661 atggataact ggtaaaaata aatctatgta taaaatatct atatcaatta ctgatttata
      721 tgaatttact aaaataccaa ttcctgaaca tctaaatgat attttagata tagagctttc
      781 agatgataca atatacatga taacaaaagt agatacaagt aaagcatcta tagaaatagt
      841 tgaaaaatca atatctcaag tgagagttgt agtacaagac cctaataatg ttatagaaaa
      901 acttgaaatg tttataaatg atgaattaat atctactaag actaatttgg aaataaatag
      961 cattatattt gagataccac aaaataaaat agtattagga gaaaataaga tactgattaa
     1021 agccagtagt cctacaggcg atttatattc aagtatgttt atatttaaat cagaaacagg
     1081 gcttaaagta aaaaaggatt ctattttaat gataaacaat aaagtatatt caatcataaa
     1141 cattactgaa aataacactg acttaatagt aacattaaat gagggattaa aggatgatat
     1201 gatggaaaac aatcctatat atcaattaat aaataaaact aaagttcaag taaaaataaa
     1261 taaatctgac ttattcaaag acatgaaact agttgaaatc aaaaaatcag actcaagtta
     1321 ccaagaaatc tatgaattag aagaagccaa cataaaaagt gctcagccta aaatcatagt
     1381 agaaaaagga gataaatgga cagctataaa acgtccatct atgattttta gatatgatgc
     1441 tgaaaacaac gagccacaag cttaaaatgg aggtgtgaaa attgtttaaa ttcgataaaa
     1501 ataaaataga acaaatcaaa caaggtagaa aagtagaaat gcagtataaa gacatttcag
     1561 acataagtat aggtcaagta aagcaagatg atgatataac aaataatttt atagcaaatg
     1621 cagaaatata tgagatgttg ttaaatcaaa gttctgtcaa tgaagcaagt aatataagca
     1681 cttttagtgt aagaaaatct ggaggtgaga gtggaatggt agaagtatat gtagctttaa
     1741 ttttaagagg caaaaaaaca atagaagaag taccagcagt aattagagag caagttagaa
     1801 ttagatgtaa agaattagaa ataccagttg aatagtaaat ttagaataac tatgtattag
     1861 ttattttttt tatgtaaagt acaaggtctt aactttaata agtaagcctt gtacttattt
     1921 tttgttatat tagaaattgt atatatattt attatttatt caatctataa attaaaccta
     1981 caatttaaag tacagaagat taaattgata atcctgaaaa tataatattg catgatgtaa
     2041 gaatacaaca aaaattaaag ctataagtat aaaaaattta gacaatagga ggctataatg
     2101 gataaattaa taaccgaatt gagtagtcta ggggcaatag gtatactatg tgctctatta
     2161 tttaaaaata ctatgcagga gaaaaaagaa gatagagaca tgtataaaaa aactgtagaa
     2221 aattttatag aattatctac acaacaacaa gaaataaaca aaaatatact tgttcaaatg
     2281 ggtataatga aaacagatgt agaggaaatt aaggaagatg ttactggtat aaaaggtatg
     2341 ttacaaaacg gtgtataaca tgaaagagta gcaccagatt atatattgtt aggaaaagat
     2401 aaagtagtat tgtagatagt gcactatttt attgagaagg atttgatatt taaaaatatt
     2461 aattaaaaaa agtaataaaa ataatatata aaaattaaaa aaggagttga gcttaaattt
     2521 gattagaaaa aatcaatttt aagacaactc ctttttttta ttaaattatt gtctattaac
     2581 caaaatagct attttagcat ctggattata acttatctga accatttgat ttttcttaac
     2641 atgttcaagg tcttcaccac cataagctat ttgtaactta actggtaact taccttgttt
     2701 tataatagca acgtactctt ttttaccttt tttctctaaa ctaatcaaat tgccaacata
     2761 aggtttaaag ttctgatact ttttactaga atttcttatg tagaagaaag caccaacagc
     2821 aataactaaa tttatgccaa gtgtaaccca agaattgatt ttaagcatag ctccagcgat
     2881 tattatcacg aacattaaaa cgataggtaa tatagctttc ttaagaagca atttacccat
     2941 tatttcatta gcctttttct cagggccact catagttttt gatctagcaa atgattgcgc
     3001 gaatttgtct cttaagccca ttttatcctc ctaattttaa taaatattta gttataataa
     3061 cgagatatta cttgaaacta aaaatttact acatttatat tatgtttgac ttttgtataa
     3121 ataattacat tcaagtaaag caaaatatac taattatttt atcataaaat tataaaaaag
     3181 aaaataaatg aaataaaaat attagaacaa agaaatgatg taaaatcgta tcaaaagcaa
     3241 cataaaaatt atttatctat tttctcatct ttatttttgt tatactcaat ttttcctaaa
     3301 tccttctctt tttcatattc atgaagtttt aattcaatca taccttctat tttggcttta
     3361 tcataatcat ttaactttct aaagttgttt aaaagcttta tttcattaga gtttatgcta
     3421 ttaaatggat agtttgagga ggaatcgcaa attaaatctg atttatgtga tagattatct
     3481 ccatttaata gccagtctac tgaaacatta aatatctcag ctatagattt taatatttca
     3541 taatttggtt ttctaatgtt tctctcaaat ttacttaagt tgtcacagcc caacatttct
     3601 tctagttcat attgtttaag gttttttgat tttctcaaat aaacaattct ttctcctaaa
     3661 gtatccataa acactctcca ttcaattaat gtcaaaaaga ctttttaaga tgtaaatagt
     3721 ttcaaattaa aggtcaaaat gacataaaaa ccattgactt aaggtcaaaa tgactttata
     3781 attaacttaa tgatacgaat ttacatccta attttagcac aaagtaatca aaaaatctta
     3841 tttagtatta aataaattta tatacttaat atgtgtacat attaaaaata tatactaaat
     3901 agagggggtg cgtaagctaa aataatataa aagtaaatat aaatcactta gaaaggaagt
     3961 tgataaatgg atgctcgaaa aaaatggata ccttttttgg gagtgcaagt caagcaaaga
     4021 cttattgaat taaatatgac tcaaagggaa ttagcgaaga aaataggtgt taatgaaaac
     4081 tatttgtcag ctattttaaa tggaagaaga acaggtaaaa aatataaatc atcaatttat
     4141 caattactta atatagaata ttcagaagat gattaataaa tagtatataa agtaggtgaa
     4201 tattcttgtg tgtaaattgg attcagatgg ggttatagag tgttgtagag caattgatga
     4261 ttttattaca gcactcagta atataaaaag cttaaatatg gaaagattaa atactttaac
     4321 taaatattct agtacatgtt caatccttct taaagagggg aattatgaag gatgtacaat
     4381 tgtgtataga aagatgttgg aagaattaaa aacatgagta atgcatttct taggaatata
     4441 agttatacat agagatgtat tatatttttc aaagtactta aactaaaata tggataaggt
     4501 aatctaaata ttataaatgt gcttgaaatt agactatact tgtttttaaa taatccaata
     4561 tccatatttt agtaatatac tacaaaaaaa gaaggttaat agatgatgta aaatcgtatc
     4621 aaattatgta tgtttaaacc attttatctt cattattatt agaggaatgc ttttttaagt
     4681 ctttatattc agatatctta agttcaagta ttccttctat ttttatttta tcacgttcgt
     4741 ttagttgtct gtatagattt aatatcgtca tttcatcatt agtaacatgt aagtaatctt
     4801 ctttatcttc ttttacacta ctattgacat ttaccttctc tttaccatag agaagccagt
     4861 cagtcgtaac attaaaataa tcagctattg acattagtat atcacaatta ggttttctat
     4921 ctcctgtttc atacttgcct aagttttcaa attttaaaat atccataagt ttgcgctgag
     4981 taagtttttt ggagtttctc aaataagcaa ttctttttcc taaagtatcc acaaaataca
     5041 ctcctttctt tttattagta atgtctaaat gacatttaaa attaaaaata tataaattta
     5101 taatataaaa ctactaaaat aaagtctaaa tgacattttg cttaaattaa tatgctcata
     5161 atatgatttt aacatattat agttgaaaat atatggttta ttttgatttg tatatataac
     5221 aataggttta attgttataa aaatgtaaag gggtgtatga atagattgta taaatttatt
     5281 tcgataaact aagattgctt tttgattgtc tgtaaaagag aaaaagatta agagaaaaat
     5341 agtattatat tgtaatttat attaatcaat tacaaaaatt ttatgaattt attctttaga
     5401 ataaaatatt taagaataag ataaatttac aatataatac tataacactc ttttatctag
     5461 ttttattttc tttatagaac aataatatta taaatgctag tagatttaca cagaatactg
     5521 ttatatacat ctgtttaaat cctgagttta gagtagattg tagtgtgttt tctatttttg
     5581 ttctattatt ttctatggaa tttatataat ccaattttga tttatcaaaa gcctttggta
     5641 tttcagtttt tacctcttgt gtctttgcta aaactgcttg gagtgatttt ttttgctgtt
     5701 gcattgtatc aaggcttttt tccatgtctt tcttttggct tatagaatta tttaacttgc
     5761 tttgtagctc tttcttttga gattccattg atcttagttt tttacttaat tcgttctttt
     5821 gagttttatt tttttgtaac tttgtattta agtcatctct tgtctttttt agttgctgta
     5881 tttgagcatt taaactttct ttttgttcat ttacatttgg tttattctcg ctggaattgt
     5941 tattcttatt ttctgtagaa tcattcttag tgtcatctga ttcagaatta ctggtattac
     6001 tctggttttg ttcatttgag ttattttcgt tatcagtagg agttttttct gtagtaggta
     6061 ttttattata agcagttgta agttccttga tggcctcatc ttgtttttca agaccttgtt
     6121 ccataccttt tataccttta tcaacaccag caataccttt ttttacacca tctattcctt
     6181 gattaatacc agctctagct tttaccatat tgtcaatacc agtttgaact cctttaatac
     6241 cactatttag tttattttca ccatcttcaa taccgtttat tccactttgt gtcccatcta
     6301 ttcctttttg tacatttttc tgtattttag taattataga tggaactttt tcatcaaaca
     6361 ttgttgttga tatttctttt gttatattgg taatgttggt tgtatctgct gactgaactt
     6421 tattaagtaa ggattttgga agtttgccac ctgtcatgtc catatttata tttgaagtat
     6481 cattcatatt tgggatagag acatttttta aattttttgc catttcaggg tctgatttta
     6541 agtcatctat catgttttca agttcttcaa gttgaactat tttaggagtt gagggctttc
     6601 caactaagtc cataatatta tcttgcacag ataatcctgc atgtgctata aatccaatca
     6661 ttatagctgg agaaattgaa gtaccaattg agcgtatcaa ggataatgtt gcaagtgctg
     6721 aattagattc ttctaatctt gtatttgata acatcatata gtttagagga gttcccatag
     6781 taaatcccat tcctaatccc ataaatatta aacttacaca tacactaaat acagtattgg
     6841 tttttagagc aattaaaact aggtaaagag agcctatcat agatacagaa aatcctagta
     6901 atagtatttt ttttgcccca aacttgtcaa taagtcttcc gcttaaagga gcagcaatac
     6961 ctgcaaataa tcccaatata gctacaaaat atcccccaga accagcattt atctttaatg
     7021 cattttcagc atactgtgga acgaatacca tacccatcat tccaatacca acaattaaag
     7081 ataaaataag tactatcaat attctcggat ttaaaaaata ttcaaagctt aaaatagggt
     7141 ctttagctct attttcaata aatatgaaaa taggtataag tacaataaat gtcaataagt
     7201 atggataaac tgatatatct tgtatagaat ttttaaaatt aaaaaagtct atattcataa
     7261 gaccatataa tagtgatacg attatacata tcaacatcaa tgtaccaagc ttatctattt
     7321 tttctttaga ttcagactta ttgtttttaa tacagaaaac tccaccaata agtatgatta
     7381 aacaaattgg aagatttaca aaaaatagcc acttccaatt ttgagttcca aagatactta
     7441 gaattgtgct accaatgctt gaacctaaaa tattggcaat accatatgtt gccccaacta
     7501 aacctaaagc catgcctctt ttattttctg ggaaggtagt tccaaattct gctgtagcaa
     7561 ttggcatgat tccaccacca ccaattgctt gaataacacg accaattaat aaaatataga
     7621 aattggaaaa tagtgatgat aatccacata ttaatgaacc actaccaaat agaaatatac
     7681 taactagata cacatatttt cttcctattt tatctgctaa ttttccagag ataggaatta
     7741 cagaagcgta tgttaatgtg tatatggtaa tcatccaaat tcccgttttt tcatttactc
     7801 caaggctatt ttgtataatc gttcttgctg gtgatactat tccagtatca atagctccca
     7861 taaatatacc taatagataa agtgtaagta ctaaaaatat ttttggatta ctgtccttgt
     7921 tcttaatact agtattatga ttcaaggtaa acaccacctt aatgtattaa tttttcaata
     7981 tagggtttta aatcttcaaa ttctatatga agatatgttg aatatgaaaa aaacattttt
     8041 attatgatat tgcatactaa tttgtcatta ttaaaaaaac tttctttttc taaagcttca
     8101 tatactttat ttgaaagctg ttcatgaaag tcgtctttgt gttttttcat ttcaaaaaat
     8161 ctctctgttt caaaagtgtt taaaaagtca ttgtattgga tattatgaac tttgtttata
     8221 aaatttctta tttcagtaaa aataatgttt agttttttta tgtaatcttc agtgttttta
     8281 ttggagtatt caattcgcct tatcaataaa tcccattcag attttgtgat atattctatt
     8341 atttcttgtt ttgaattaaa gtaattatac actgtacctg cacttatacc acacctttga
     8401 gctattttcc ttatgctaat attcgagtaa tcttcttcta aaatcatatc ccgagacact
     8461 tttaatatat cttcttttac attttctaaa atctttggca tattaccacc tcttttatta
     8521 aaattattat gaacactgtt tattatactc ctttaaaatt tattaatcaa tatgtaagct
     8581 ataatgtata atattattat atagatatga tagaaaataa gtgtcttctt actaaatatc
     8641 tattatatta aatttgtact taagtatgat tatttattga aatatgtgat attaaatttt
     8701 tctttttaat aaattaaata ttatatgata aggagaatat ggtgatggaa aagaagtatg
     8761 taatggcatt agaccaagga acaaccagtt caagagctat actatttaat aaaaaaggcg
     8821 aaatagtgaa aattgcacaa aaagagttca atcaaattta tccaaaagct ggatgggtag
     8881 agcatgaccc tatggaaata tgggggtcac aaagtggggt aatgagagaa gttatagaaa
     8941 cagcaggtat aagaccagaa gaaattgctt caatagggat aactaatcaa agagagacta
     9001 cggttgtttg gagtaggtat actggtaaac ctatttataa cgcaatagta tggcagtgta
     9061 ggagaacgtc agaaatatgt gatgaactta aaaataaagg attggaagaa tcaataaaag
     9121 aaaaaacagg tcttttaata gatgcatact tttcagcaac aaaagtaaaa tggatattag
     9181 ataatgtaga aggagctagg gaaaaagcag aacaaggaga gttattattt ggaactatag
     9241 atacatggtt aatatggaat ttaactcgtg gaaaagtaca tgtaacagat tactcaaatg
     9301 catctagaac aatgatgtac aatataaatg atttagaatg ggatgaggat atattacgag
     9361 aattggacat accaataagc atgttgccat tagtaaaacc ttctagctat gtttatggtc
     9421 atacagatga gcgcatgtta tcaggagcta aaatacctat tgcgggatgt gctggagacc
     9481 aacaagcagc attatttggt caaaattgtg ttgaagaagg tactgcaaaa aatacttatg
     9541 gaacgggttg tttcttgctt atgaatacag gcagtaacat agttaaatct aagcatgggt
     9601 tacttacaac aattgcttgg ggagttgatg gaaaagtaac atatgcatta gaaggaagta
     9661 tatttattgg aggagcatct gttcaatggc ttagagatga attaaagata attgaatctg
     9721 caaaagatag tgaaatgtat gcaaataggg tagatgatac taatggtgta tatgtagtgc
     9781 cagcatttac aggtcttgga gctccatatt gggatatgta tgctaggggt tcaattttag
     9841 gacttacaag aggagcaaaa aaagaacata tagtaagagc cacattggaa tcaattgctt
     9901 atcagacaaa ggatgtttta gaagcaatgc aaaacgattc aaaattaaaa ctaaaatcat
     9961 taaaagttga tggtggagca agtaataata attttttaat gcaatttcaa tcagatatat
    10021 taaatgtaga tatagataga cccaaaatag tagaaactac agctttagga gctgcttatt
    10081 tagcagggtt gtctgttgga ttttatattg gaagaaatga aattacttca aagtggtcag
    10141 tagaaaaaga gtttaatcca aatatgagtg aagagaagag atgtaaatta tataaaggat
    10201 ggaaaaaagc tgtatcgaga gctttaagct gggaaaaaga agatgaattg gatatttaaa
    10261 aattaatcaa aattaaattt atttgaattt aaaaagagct ttatgtaaaa tatgaagctc
    10321 tttttttgtt gttaattttg catttttata taatcatact aaattatata atttattttt
    10381 cgttttcata taaaaacatt ggtatagaat tgtaaatgtg ttggtcacca actactaaga
    10441 gaatgtctcc ttctaaaaat tcaatatatg gtccaggaga tattataagt tcttcacctc
    10501 ttttaattgc aactattgta gcacctgtat tttgccaaaa tttagtttgt gcagctgttt
    10561 gaccaatata tttgcaatta gaatttatgg tgaactgaac gggcactaaa ggattgatta
    10621 tttcaagtct gttagaatag tctaaaattt tatttatagt atctaatatt tcattttcta
    10681 aattagattt agtatctatt aaattataaa gtgttgattt atatgatgat atatttgtaa
    10741 tatctctata tttttttata aaagaagaag ctttgtctgg agatagtaca ataacacctt
    10801 taccctttat gcttttaaca acgccaatgt cctctaaaat tttgacagct cttcttatcg
    10861 tttctggaga tacattgtat ttaccagcca aaacagagcg tccaaatagt actgaatcct
    10921 cttgtatttc acccgtgtat attttatttg caatatccaa cgctattttt tggtatattg
    10981 gcatcgtata gtttttatcc attgtttttc ccccaataca aaatttatgt taaaaaaata
    11041 tataatctta acaatactat tgtataattt ataggtttat atgtctacaa tatgtacaaa
    11101 tattgtgcat gttttaaaat aatattttaa catgcattta gtatacatga ttttattata
    11161 cttaaaacta tataaagaat taattataaa aatataaaga tattttactt acaaagaatg
    11221 ataattatat agatgaaaga aacaaatgaa tgaagaaaaa tgattctgtc ttgcatataa
    11281 agtgattaaa aatgaaaaat actttaaaaa tgaaggttaa agcccttatt ttaagtgaaa
    11341 ataattaatt attaactaaa aaatggtaaa aagatttttt gaaaaagaaa tacaaatgaa
    11401 tgttcaatta aaataattgc aaaaatattc cttaaatggt aaaattatat taattaaatg
    11461 caatagaata gttgcaaaaa taaaattgaa tacaagtgat aaaatatttc atgcaatata
    11521 taaaataaac aaaatttaaa aattaaaact acttattcta tcaaaatgtt agcgaggagg
    11581 ggtcataaat tgtataaagt agatttaaat agtgatttag gagaaagttt tggaacgtat
    11641 aagattggtt tagatgaaga agttttaaaa tatatttcat cagctaatat agcttgtggg
    11701 tttcatgcag gtgaccctag tcatatggaa aaaacagtac agctagctaa aaaaaatgga
    11761 gtgaaaatag gcgcacatcc aggtttccta gatttaatag gatttggaag acgtgagatg
    11821 aaaataacaa agcaggaagc taaagattat acaaaatatc aattgggtgc tttaacggca
    11881 tttgcaagtt caaatggatg taatatacaa catgtaaaac cacatggagc attatacaat
    11941 atggcagcta aagataaaga gttagctatg gggatttgtg aagctatata tgaagtcgat
    12001 aaagatatta tactgttggg gctatataat agtgaaatga taaattctgc taaagaaatt
    12061 ggacttaggt ttgcaaatga agtatttgca gatagagctt atgataataa tggttttttg
    12121 gttccaagaa atgtagaagg agcagttata catgatacaa aacatgcaat agatagggtt
    12181 gttaggatgg taaaagaagg aactgtagaa actttaacag gtgaagttat acatatcaaa
    12241 gcagattcta tatgtgtaca tggggacaat ccaaaagcaa tagagtttgt caaagaaata
    12301 agaaagcgtt ttgaattaga aggtatagaa gtttgtccat tagaaaacat agaagtttgt
    12361 tcgtcagaga acatagtata agactgataa catgaggggg agataaaata tgagtacaaa
    12421 aaatattaca gataaaacta aaaataaaaa agatgtcgga gcacttatag gggctgcatt
    12481 tataatggca acatcagcaa ttggaccagg gtttttaact cagactgcac aatttaccca
    12541 agattttgga ccaaattttt catttgtaat tttaattaca acaatccttt ttataggggc
    12601 tcaagtaaat gtatggagag taattggtgt atcaggactt agaggtcagg atatagcaaa
    12661 taaaataata cctggattag gttatttagt agctttttta gtagctcttg gaggattagc
    12721 ttttaatata ggaaatgttg gtggagctgc acttggtatg aatgtaatgt ttaatatgaa
    12781 tatgacatta ggaactgtat taagtggatt aatagctata tttgtattta tgtcaaaaaa
    12841 ttcaaattct ctagtcgata agataactaa atttttagca ttaggaatga taattatagt
    12901 tggatatgta gcaatatcaa atcatcctcc tgttggagag gcagtatcaa gaatggtaaa
    12961 accagaaaat ccaaaaggac tgatattccc aataataact ctacttggag gaagtgttgg
    13021 aggttatata acttttgctg gaggacatag attaatagac ggtggaataa caggagaaga
    13081 aaatataaaa gaaataacta aatcttctct tttgggtata ttagttgcca caatgatgag
    13141 agttctttta tttttagcaa tactggcagt ggtttcaaaa ggtcttcaac ttgacccaga
    13201 aaatccagct gcttcagctt ttaaatttag tgcaggagca ataggatata aattctttgg
    13261 acttgtatta tggtctgctg caattacatc agttatagga gctgcttata catcagtttc
    13321 tttcttaaag acactaaatc cttttataga taaatatgaa aaatatttta taatagcatt
    13381 tatagcaata tcaacactta taatggcatt tataggaaaa ccagctactt tattaatttt
    13441 agcaggagct ttaaatggat tgatacttcc aatcacatta ggaattatgc ttatagcatc
    13501 taaaagaaaa gatattgttg gagattacaa gcatcctaca tggcttttaa tatttggatt
    13561 aatagtagtt ttaatatctg catatacagg aataacttct cttagcagcc taggtgcttt
    13621 atttgcttaa tttagaagag gtgacattta tggaaactag atacttgata tcaggggata
    13681 aggcagtggt tgctgaattt ggaaatgaga tatcagaaga tataaacaaa aaagtaattt
    13741 catttatgag agcaatagaa atatcgaatc ttaaaggtat tgtaacagaa atggtaccaa
    13801 catataggtc acttatgata agttataatc cattagaaat agattttgat agtttgattg
    13861 agaatttaaa aaaaatagaa gataatttgg aaagtatagt attaccaaaa cctaaaatac
    13921 atgagattcc agtatgttat gatgaggttt ttggtataga tattaaaaac gttgcaagct
    13981 acaataatct cactgtagat gaagttataa aaatacacac aagcagagag tacttgatat
    14041 atatgctagg gtttactcct ggatttccat atctaggtgg tatggatgaa agaatagcta
    14101 cacctagatt agaagtgcca aggactaaaa tttatggtgg gagtgttgga atagcaggtt
    14161 cccagactgg tgtatatcct attgatagtc ctggtggatg gcaaataatt ggtaggacac
    14221 ctttaaaatt atatgatgaa aatagagaag aacagatttt gcttagagct ggagatttta
    14281 taaaatttgt tccaataaca ttagatgaat ttatagaaat cgaaaaaaat aacttaagta
    14341 tttaaatatc gttatagtac agggagtggt atatatggga ttcaaagttg aattaggagg
    14401 tttccaaaca ttaatacaag acagaggtag agttggctat ggtcaatatg gtgtatctgg
    14461 atgtggagca atggatgagt atgcacatag agtaggaaat atattagtag gaaattctga
    14521 agatgaggct tctttagaag ttttaatgtt aggtcctaca attacctttg atgaatatac
    14581 gcaaatagca gtaactgggg gagatttagg ggctaaaata aatggaaaag aaattcaaaa
    14641 ctggaggtca tatcaaataa atccaggtga tgtattatca tttagaggtg tgaaatcagg
    14701 tgctagagcc tatgtgtcaa tagctggtgg aatagatgtt ccacttgcaa tgggaagtaa
    14761 gtcaacttat acaagagcta aaattggtgg atttgaaggt agagcactta aaaaaggcga
    14821 ttatataaat acttttattc aggaaaaaga ttttacaata aataaaaaat taagttcaaa
    14881 atatattcca acttatagtt cagaaatcgt actaagaatt gtaaaaggtc ctcaatttga
    14941 tgctttttct aacggtgaag tagagaaatt tttatcaaat aaatacaaag ttacaaatga
    15001 aatagataga atgggttgta gactagatgg agagagtata aagcacctta atggagcaga
    15061 tattatatct gatggtattt cttatggagc tatacaagta cctggtcatg gaaaaccgat
    15121 tataatgtta tcagatagac agactagtgg tggctatact aagataggga acgttataag
    15181 tgtagatttg tataagttag cacaagcaaa gccaaatgat gtagtaaaat ttgaacttgt
    15241 agatatatat gaagcacata gactattgag agagcaagaa gataagattc aagatatcta
    15301 caagagtatg aaaaatataa gagttgtaaa ggcaaaagta ttaaatgata tagcagttta
    15361 atttaatttt aacaaataca atttttatta taatttataa tataacttac aaatagctat
    15421 ttactattta ccataattaa gatggtttag attagtcaaa tagctatttt tttagtttga
    15481 gtaaatattt taaatttaaa taaatacttc aaatttaaaa taaaagcaat atttaaatct
    15541 attatattat ctacaaaaag taggtgtgtc atattgagtt tatttagatt ttattggcca
    15601 aattggaggt gatataactc catatccacg agctattgta tctttacttg gattgatgat
    15661 tttatgtggt acattagctt ttataaatgt tgagtcacct ggatttaatc taactacctt
    15721 ttcacccata caaatatcaa ccacaccact cgttaccacc ataatttctt ctgatgcatg
    15781 atatatataa tctttggcat cctcactttc tggtttaagt tcaaactcta caaataaaat
    15841 tgaaggtgta aactcagttg taggcattgg agatactatc tcgtaaaaca tttcactctt
    15901 tggaaatttc atcataactc tatcttcttt tctaatgact aaatcatcag tattattgtc
    15961 atccataaac atatataaag gagtgtctaa aacttcagcg atttttctca atgaagacaa
    16021 ggatggttca atagcatctc tttctatttg agagatataa cttatagata aatctgtcaa
    16081 tttggaaaca tcacttaatg tttttttctt gctttttctt atatttctca tcttttcacc
    16141 tagcataaga acctccaaat aataaaatta atataaaata ttcgcttaaa acaaagtaat
    16201 tatagcacaa catagaagta gtggcaataa gaatacatag tagattttga caattaaaat
    16261 ttaattaaat ccaaataaaa gtctatgaaa atgaattatt gttaaattaa tacaaagaaa
    16321 ataataataa aaaaatttaa tagaagagta ttaattgaat taagattatc acattatatt
    16381 ttggaaaaga gtaaattttc agtaaattat cttgacatat atattgaagt aataatataa
    16441 tttaaagtat aaaattttaa aaattgaatt ataacttcaa aaaataagga gggtaatatg
    16501 aagataacag atatcaaatt tgaaaagctt agaattaaat taaaaaaacc tgtagtagtt
    16561 tcatttggag taattgaata tggagaaagt gtaattttaa aaattgaaac tgatgaaggg
    16621 tattgtggat ttggcgaagc agcacctctt gcagcagtta caggtgaagt tttggataat
    16681 gttctttcag tattgcttat gtttaaaaaa gagttaatag gcaaagaccc actagatatt
    16741 gaaaccatac ataccatcat ggatggaatt attataggta atacttctgc aaaagcagct
    16801 attgacatag ctttatatga tattaaagga aaaattatga atgcacccct ttataaagtt
    16861 cttggaggat ttgatagtaa agtccaaacg gatattacta taagtataga taagccagaa
    16921 aaaatggcag tagaagcttt agaaagagta aaagaaggtt ttaggatatt gaagcttaaa
    16981 gcaggtataa atcctgaaga cgatattgaa gctgtaaagt taattagaga agccgttgga
    17041 gagagtataa gaattagaat tgatgcaaat caaggatgga acgtaaatag cagtataaat
    17101 actatcaaaa agttagaaga atttaatgtt gatgcaattg aacaagcact tccacattgg
    17161 gatttagatg gtactgctta cataagaaat aaaagtaaca caaaaattat gatagatgaa
    17221 tcattacatt caccaataga tgcaattaag gctataaaaa agaatgcagt tgatacattt
    17281 aatattaagc tgatgaaatc aagtggaata tatcctgcta taaaaatcaa caacatagct
    17341 gaggcaagtg gagtaaattg tatgttagga tgtatgctgg aaacgagaat tggtataaca
    17401 gcagcagcaa atttaatagc atctaaaaag aacataacag aagctgacct tgatagtttt
    17461 atgttttgtg aagaattaga aggtatatct ggaggatttg taatggatgg agatattatg
    17521 aatcttgtca ataaaccagg tttaggaata gaagtaaact tatgataaat ttggaggtta
    17581 aatatgaata cacttttttc aaatccaggt agtatacttg ctgtaatgac atcaatgatt
    17641 gcattgggtt tttacttaca aagatacaaa gccattaaaa gcttaggacc agcacttaca
    17701 ataatcataa tgggaataat actttcaaac ttaaaagtag ttccagtaag tactgagtta
    17761 tatggaacta tttcaacata tgctattcca gtttctatga ctataatgtt gatgagtgtt
    17821 gacttaaaag aaatgacaaa attatcaaga gaacctttaa ttgcaatttt tgtagctgta
    17881 ttaactgtaa gtatcatggc atttttattt ggattagtat ttgcagaaaa aatatcagaa
    17941 ggttggaagg ttgctggaat gtttgtaggt acatacactg gtggaagtgc taatcttaca
    18001 gctattggaa caggtcttaa tgtaagtaga caaactcttg cagcagcaaa tgcagcagac
    18061 tatgtaattg gagtaccaac attgatattt atgtttgctc taccagcaat attaaaaaat
    18121 tcaaagaagt ttaaaaaact ttggccatat catgtagaag aatcagaatt agaagattgt
    18181 caaaatgaag aatttatgga gtcaaaagaa tggagtatta aagatatagc ttggatgttg
    18241 gctataggtt ttgttgttac agaagtttca acaatacttg ctggatattt caattcaagt
    18301 tttagtagtg cagcaagaat acttttagtt acaacaattt caattataat tgctcaatta
    18361 aagccagtaa agaaactaaa gggaaattta gatttaggat tatttgttgc attattcttt
    18421 ttatgtacaa taggtttttc agtagatata aaagagtttt taggttcaac ttttactata
    18481 acactttact gttttagcat aatttttgct tcatttgttt ttcatttagg cataactaga
    18541 cttttaaaga taaagtatca atatgtaata ctttctatag taggagcaat tgctgatggt
    18601 cctacttcag ctttagtagc tgcttctgca aagtggaatt cgcttgtaag tgtagcagtc
    18661 gtaatgggag taattggtgg agtattagga aattatgcag gtatatcagt ggcatatgca
    18721 ataaagatgt ctctaggatt atagggggga gtttaattga taaaatttaa attatacata
    18781 tctggactat acagtggaaa tgtaatcttt gatggagatt tattaattga aaaattgaat
    18841 ccttttacaa ataaaataga aagtttaaaa ccaataagca aagaagaaaa tacatactat
    18901 ttaaatctta caaaaataga tttaaagtct ttatttaata attttgatgt atatactaaa
    18961 agcttagtaa acacagataa agacacagtt ataaataact taggagaaac gcattctaaa
    19021 cttaatgaat atatatgggt tcaaagaaac aaaaagttcc cactagatat aattattgta
    19081 gataataaaa tagtaggttt tatctgttta tccagagaaa cttgtactat attaattatg
    19141 gatggatatg aagagtatac tgtattaaaa gaatgggaaa aaactcataa aaatgaagag
    19201 atatattcta taagatttgg tggaaattat atgattgata tgaaagatgg tataaaactt
    19261 tctacagatg tatatctccc tgattttgta gattctgcca aaaaagcacc gacaattctt
    19321 atgagaactc catatggaaa agaaaatgat aaagaaatat attataaata tgtacaaaga
    19381 ggatatgctg ttgtaataca agatgttagg ggaagaaatg aatcagaagg taagtgggaa
    19441 cctatgattc atgagaggga agatggagat agtaccataa attggatagt atcacaggaa
    19501 tggtcaagtg gaatagttgg aatgcttgga gcatcatatc ttggttatgt ccaatgggca
    19561 gctgcatctt caggcaataa gcatcttaaa gctttagtta gtatagtaac atcaggaagt
    19621 ccttttattg atataccaag aaaaggagga gcttttgtat ctggtatgct tgcatgggca
    19681 tttatggtat caagaaataa agttgataga agcaaaatgg taagagatga ttgggatgat
    19741 gttttaaaca tacgaccaat agagaatata cctgttgaag ctcttggata tagaattgaa
    19801 tttctggaag aatggttaaa gagagtagaa aaagatgagt attgggattt gatggattgg
    19861 catttacaaa aagataaaat aaatgtacct gcattggttg tatctgggtg gtatgatgat
    19921 aatagtatgg gaactacaga ggccttagat gttataaagg actatgaaaa aggaaagaga
    19981 aaggctattc taggtccatg gatgcataat tcaaatactt taagagatat aaatggtatt
    20041 tctttaggaa atagttcatt aagatatgat ttggattata attatctatt atggtttgat
    20101 aaatacttaa aaggtataga aaataacata gatacgactg ctccagtaga gtattactct
    20161 gtaggttcta ataagtggaa gacagaagaa aattggccaa taataaataa gatagataaa
    20221 agtatgtatc taataagtga tggaaatgct aacacatctt taggaaatgg tagattagta
    20281 tttgataatg atttagaaga aaagtatgat agttatatat ataatccaaa agacccatca
    20341 gtacaactaa ttgatatgtc agagaatgaa gttggagttc caaataacta caaagattta
    20401 gaaaaaagaa gtgatatgtt gtgttataca tcagatgctt ttagtgaaga atttactgta
    20461 acaggtgata taaagttaga gttttttgca tcaagttctg ccaaagatac tgactgggtt
    20521 ataaaaatta tggacgtgga tttagatgga aattcaatta aattagctga tggtatactt
    20581 agtgctagat ttagaaatag tttttataag tcagagttta tggaagaagg agagatttat
    20641 aagtttacgg ttataacttc aaaaatatca aacacgttta aagttggtca taaaattaga
    20701 ctagatataa catctagtgc taaaaacttt attttccaaa atagcaacac gacagaggga
    20761 tataatagta ttgaatatat agaagcaaag aatacgattt accatggagg taaatatcca
    20821 tctaaattga tattgccaat agagaataag taaatttata tagattaaat agtgaggagg
    20881 tgtctcaaaa tgaatttttt agttcgtgag acactttctt ttatacgaaa tcaaatatat
    20941 tttcatcatt tcaacaatga aaaagaggct tatctctctg ttttgagata gcctcctata
    21001 agctaaattg attattttgt agctgcaaca acgctcattt caactaacaa atgctctcta
    21061 gcaagtctag cttcaacaca agctctagca ggttcaaacc ctttttcaac ccaagcatcc
    21121 caaacagagt tcatagcttc aaagtctttc atatctctta aataaatagt aacagatagc
    21181 aaatgttgct tatctgaacc atatttgttt aataaatctt ctattttagc taaaacttca
    21241 gttgtttgtt caattactcc tccttcagca tgagtttgtc cacataaata aactgtattg
    21301 ttatgaacta cagttctact cattcttcca gttccttcat atctctttat ttccatattt
    21361 taaatacctc catagttaaa aaatctatta aaaatctaaa taataaatta aaaaaagtct
    21421 atactatata aaattatatt atatattctg ataataatcc ataaaaacat ataacttttt
    21481 agctataatt attattgtta ttaattgaaa agatttatta gttacttgac atagtttaca
    21541 cttttaatta tagtataaat tggaatattt agataattat tatttaatgt ataagctaag
    21601 tttttaatta atatggcttt atacatttat atagaaaaga ggtacgtatg agtagcacaa
    21661 tcaaatcaaa tcgaataaaa ggtataatgt ttataatagc atcagcgctt ggctttgcaa
    21721 tgatgtctgc attcgtaaag ctagctggag atttaccaag ttttcaaaaa gtgttcttta
    21781 gaaatctggt atcagctata atagcttttt ggcttatcat aaaacataaa ggaagtctaa
    21841 ctggtaaaaa agaaaattta aaagtacttt tatataggtc aatatttgga actctaggag
    21901 ttatatttaa ctactatgca attgacaagt tgatgctttc agatgctaat atgctaaata
    21961 aaatgagtcc cttccttgta gtaatatttt gtgcaattgc tctaaaagaa aaaataaatg
    22021 taaagcagat aggagctatt ataattgcat ttataggagc tttattcata ataaaaccaa
    22081 catttagtgt agaagtaatt ccatatcttg gaggaattgc aggagctgta tttgcagcaa
    22141 tggcatatac ttgtttaaga gttcttggag atagagaaga ttactataca attgtatttt
    22201 tcttttcagt tttttcatta gttactgtag ggccaattgc ttttgcagta tatgaaccaa
    22261 tgacccttat gcaacttata tatctattac taggtggagt atttgcaagt ctaggtcaat
    22321 ttggaataac tctagcatat aaatatgcac ctgctaagga aatctctata tttgactata
    22381 gtaatataat cttttcagca attttaagta tattcttatt caatgtttat ccagatatgt
    22441 taagtgttgt tggatattta atagtatttt cggcagcatt ttatatgttt ttatacaata
    22501 agaagttaga taaattagac aaagaaaaga agaagtaaac tagataaaag tgtttttata
    22561 atttgtattg aatatttaag tctttgtatt aaaattaaag aaaatttaat taaaaatgtt
    22621 tggtatatta acttataaca gcagttaaaa ttgaaaaatt ataactgctg tttcttttat
    22681 taaaaatatc caaatgtctg taaaaataga ctataataga gtagtataaa taatataaag
    22741 gggataaatt aaagtatgga aaaagtgaaa gttgctgtga ttggagcagg taatagagga
    22801 acgtatgcat atgctccata tatttatgaa aattctgatg tatgtgaaat agttgctgta
    22861 gcagaaccta aaaaaggaag acgagaacta tttacacaaa aatataacct agatagtaaa
    22921 aatgtatttg aaactttaga agactttttt aaacatgaca agatggcaga tgcagtaata
    22981 atagctacaa atgatgatag acattatgat gtagcaaaac tagctcttga aaaaggttat
    23041 catgtactat tagaaaagcc aatgtctaat agtttagatg gtttggtaca tatagatgac
    23101 ttgtgtgata agtataaaga taagattttt atgatttgcc atgtactgag atattctcca
    23161 ttttataata aattaaaaga aattgtagaa agcaaaaaat taggagagct agttagtata
    23221 caatataatg aaaatatagg atattggcat tttgcacata gctttactag agggaattgg
    23281 agaaatagca atgaaaccag ccctttaatt ttagcaaaga gttgtcatga catggatatt
    23341 ttgttatatt tagtaggaag tagatgcaaa aaaatatctg catttggaag cttaaagcat
    23401 cttaataacc aaaatgctag tggagagatg gcacaaaatt gtcttcagtg tttagttgaa
    23461 aaaaaatgtc catattcagc aaagagaatt tatttagaaa aagatagaag tataaataga
    23521 gctgttcaca taaatccaac tgaagagaat ctattaaata tacttaagac aagtccatat
    23581 ggaagatgtg tttacagatg tgataataat gttgtagaca atatggtaaa tatactacag
    23641 tttgaaaatg gagtgacggc tacttttaat ttatgtgcat ttactaaaga aaatggaaga
    23701 actataaagt taatgtttag ccatggtgaa gttggtgggg atttaaataa aaatgagata
    23761 agaattaaag aatttggaaa aaacgaagaa atagttatga atccatcaaa tcaacagaat
    23821 atggtagagg aatatgatag aaatcttata gctgaattta ttaaattagt ttcaaataaa
    23881 gaactagaaa agggtagagt agcagcaaaa gaagctatac aaagtcatgt aatggcattt
    23941 gcagcagaat attctagggt cagtgatgaa gtagtgtata tagaagaatt ttttgatagt
    24001 gctaagcaaa tgactaagga gatagaagaa actatatttt aattaataaa aatttattaa
    24061 ataaaataaa gatagattaa ataatagaaa tacgaaaata tgtgttctat taaggaatct
    24121 atctttttta ttaaggtttt ttcttatccc tatcaaaaaa atccatacat tctgataaaa
    24181 gataagaaag taaagcgaat aagatttctg tacttaaagg aatcgttact gaatccataa
    24241 aggtatcaat tatgttcata gctagaaaag ttagtataaa atcaattata aattcgcaaa
    24301 gtttatatat tgagtatggt aatttgttta catatctgaa tatatctaaa atagtagtgc
    24361 atagaaaatc aattggagtg gttatacaaa aatatattaa aaagaaaatt aatacagctc
    24421 caagagattt atattcaaat cctaagaatg ataagaagcc aattcctata accgtgaaaa
    24481 tacaaaaagt tataccaaaa aaaacagcaa aaaataaaaa tacagaaata aattcgccta
    24541 aaggaatcct tcttttatta cttatcttaa tcaactcctt aatttatgat atgaaattta
    24601 tataaataat aacattctta aaaattcata atagtcctct gtttcaaata gtactgtttg
    24661 agaatctatt tttttcatat ttggataaaa agaggcctta aaagctttat aatgttctct
    24721 aaattttatt tctatcttaa atttatctgg caattttatt aagtgcctag ataaatctcc
    24781 agataaagct tttttgacac ctttttcaat tttttttagt gcaaggtttg gatggattga
    24841 aattgaacca tttccaattc cttttgacac aggaacagtg actatatttg gatttagttt
    24901 ttttgcactc tcacaaagca tttcatctcc acttaaaaat gctacaggaa cattataata
    24961 tgcagcaata taagcattta tagtaaattc agatgctatt tcatcattta ttttaaaata
    25021 gtcataatca atatccatag tatgggaaag tggattacca ttacaagtag ctccagagtg
    25081 atagccagtg aatatacatg catcaaagct ttcatcaatt ccagccatca taactagtgg
    25141 gtctttggtc catcctctaa gtattttgac gttttcaggt aaaatatttg gattaatatt
    25201 tctaccactg tcatgtgcat ctttaacaag tatttcatgt acaccagatt gagtagctcc
    25261 atcacatgct gctgttatct ctttactcat ttgtgttcta tagtgttgcg aaaattcaca
    25321 ttcaagtttt gtttcatccc aatttacaat accacaagta ccttctatat cagcacttaa
    25381 atacaatttc ataatatata cccccttatg tttattattg atgataataa cagataacag
    25441 aaaatacata atcaataaag ggcataaaaa tattatgtct tactattaac tattattaaa
    25501 tctgtaactg aaaaataact aaattggtat aaaaaaatat aacactatgt gtcatttatt
    25561 tatatagttt tttatatctg atgtttatat aaaattgtaa catataagtg gttacattta
    25621 ctagtttaac atagttaaaa tagttaggta ttatttttaa gttaaattga ttattataaa
    25681 atcgcagaat aaaagaaaaa tttaatttat taaaatgcat gaaatgtttt ttcctcaaca
    25741 taatgctaaa ttaaactcaa aaagaaataa tagaaaaatc ttatgtagct tagaaagaat
    25801 gtgaatgatt taagggaaaa atagaaattt attatataat attaggctgt attatataat
    25861 acagcctaat attatatgta tatgtgacat aaaatcttgg taagtgtaaa taaaataaat
    25921 gtggaaaaca agttaatgaa atcaagaaaa aagtaattta aaattcaatt tcatcttccc
    25981 aattaaattc tcctgatttt tctacactct taggccagtg actacaccat ttaggaacgg
    26041 acggattttc aaccctatca acgcttggag tatatggctt taagtcaata acaggactat
    26101 tatcattagc atcaatatat ggtattttta ttatgccatt ttcatggtcg atattgataa
    26161 tttgtacagc agtcaatgct attggattgg gtcttatagg tgaccttgtt gcaaatattc
    26221 ctataacgtc tggtccactt ttataaggtt ttggggtttc taaaatactt cttagttcag
    26281 gatcatcaaa cccatcagcc caccaaaata catttaaatg actgaaatcg tcgagttcat
    26341 ttaatgcagg tacatacttt ttgtctaatt taataaagac ctcttcgcct tgaatacata
    26401 ttttacctat aggatttatt aatatttctt tcataatatt acctccaact atttaattta
    26461 tcatttgtaa ttttagggta taacatgaca tcatgtgagg gtcaatataa aataataaat
    26521 aaaaatatta atagttagaa tgataataca ttttttacat ggagcatgac accagtaata
    26581 aggcaatctt cgtcaatatc aaaagtagag gtatgcaaag gggaagtaat gtttttttca
    26641 cgatttgcac aaccaaggtg gtaaaaagct ccttcacagt gtcttagaaa atacgaaaag
    26701 tcttcagccc caagagtggg cgagtcttta aggataatat tttcttcacc aaacaattct
    26761 acagcatttt gtttgacgta atctactaga tggtttgaat tgataagagc tggataacct
    26821 tcctcaattt caacagaaat acttcctcca aatgttttac aagtaaaatc gcaaatttct
    26881 ctaattcgtt tttttgaaaa ctctctagtt tcaggagtca aggttctcaa agtacccctt
    26941 ataaccactt tatcacaaac tatattttcc ttgattccac cttcaatctt tcctagagaa
    27001 ataaccacag aatcagttgg atttgtgttt cgactaacga ttgtctgtag agctgtaata
    27061 atatgagcag atataacaat agcatcaata ccttgatgtg gataagctcc atgacatttt
    27121 gaaccatgta cagttaattg aagtgtatcg gtggaagcat ttagagtgtt gtattttaat
    27181 tcaattagat ttttgttgat attgggattt acatgaagtc caaatatata ttttacattt
    27241 gggttttcaa gacatccatc ttctatcata agttgagccc caccaatagt ttcctcggca
    27301 ggttgaaaaa agaattttac atttacattt aagtaatcct ttaatttaaa tagtatatta
    27361 caagtaccca gtaaaatagc agtgtgtgca tcatgaccac atgcatgcat tttgccaata
    27421 ttagtagatt tataagaata attaagttct tctgttatag gtaaggcatc tatatcagct
    27481 cttatagcaa ctgtttcaaa gtttggactc acgttaatgt atgcagttat ccctgtatga
    27541 ttcttatatt caatataatt tatacctatt tcatttaagt atttaataat ttttttctta
    27601 gtttgaaatt cttctaatcc aagttctgga gtcttatgta aatctcttct tatatttata
    27661 acccaatcat ttatctcatg acaaagagtt tttatattaa gcataaaaaa catcctaact
    27721 atattaaaaa tttatttttc ttcattaatt atattatttt atgtaaatca ttattatgta
    27781 tcaagtacaa ataaaatatc ttataattat attagagata tttagtatgg agaagaatat
    27841 atcattttat aagaagaggt gtttaaatgt taggaataat tgcgccatct gggccattaa
    27901 gaaatacaag tttggaggaa ataaagttta atttagaaag ttatggttac gaagttaagt
    27961 tttctgaaag ttgtagttta aattataaag gttatttagc tggtaatgat gatattagag
    28021 caagggatat agaagatatg tttttagata aagatgtaga tataattatg tgcttaagag
    28081 gaggttatgg aacaacaaga atattggata aaataaatta tgatataata aagcaaaatc
    28141 caaaaccatt tataggtttt tctgatataa caggtttaaa tttagctttc tataaaaatt
    28201 gtggtctttt accatatcat ggaataatgg cagcaaatgt aggtaaatgg gataaattta
    28261 cctataaatc attggtaaat gctttagaat ttaaagatga attatattta gaaaatccaa
    28321 aagaagaaaa gatttatact gtatgtgaag gtaaagcaga gggaataata atgggaggaa
    28381 atttatcctt aataattgcc acaatgggaa caaaatatga aatagataca aaagataaaa
    28441 ttttgtttat tgaggaaatt ggagaacctc aatataaatt ggatagaatg ttaacacaac
    28501 tatattcttc aggaaaactt gaggaatgta atggtataat ttttggagat tttaaggatt
    28561 gtattgaaga aaatgatttg atggaattac taatagaatt tgcaaataag gtcaataaac
    28621 cttctatata taatcttcag tcaggacatt gtatcccaat gataactatt cctttgggca
    28681 gaatgtgcga attagatgct acagaaaaaa tcgttaaatt aaaaaaatag tgtgtatata
    28741 aatataatag aaatatggta taatcttata caagtaaaaa tttagctagg aggatgaaaa
    28801 atgtctgatg atagaataat agactttaac gaactaaaga acaaagttaa agattctgat
    28861 gtagataaat ttgagcaata catatataac ttatattttt ctgttatgga tggaaagatg
    28921 tctatggctg agttttcaag aaaaatattc gattatatga gagataacaa catatctcaa
    28981 gaaaaattta tgaaaataca aaagcaattt atggagagat atggtatgga cactgaagaa
    29041 gtagaaaaac aacttagaaa ctttggaatc gacccttcta cagcaggttt tatgagtaat
    29101 aatacttcca gcaaagtatc tacagaagat ttagagtcat ttaagaagag tgcaggattt
    29161 tatgagaaat atggagaaaa aatccaacca aagagttgta taacaacatt tataaaaaat
    29221 gacttaaatg atattaatgt aataatcgac caagaaaaga taatgctttg tagtgataga
    29281 aaaataaatc ttatggattc agaactaaat gagtttttat tagaatataa gaatatgttt
    29341 aataaaaaaa taaaggtagt aatgtgcgaa actacgaata agtatgatta ttaaaaaatg
    29401 aatttaaata ctgaagtagt ataaattaat tgtactactt aaaaataaaa atcgcaattt
    29461 attattcctt ataaatttgt ataaggaata tctaaactgc gattttttat attgtgaaga
    29521 ttagtcataa tagatagtgt tttaaattgt aatcttctca ctaaaactgt gtttttctat
    29581 tagaaatttt attaaaaata aatatctgat aattgtatta tatgggatgt aaagtattag
    29641 aggcttaacg aatctctttt aatacattaa ctccattttg aatcatactg ttgaaaaata
    29701 ctaagtttaa aatctcagca gggtgaacgt taggaatatc ataagtatct actaaattca
    29761 taggtacaac tatatttttt tcaatattat gttgattaaa atatgatttt agagttattg
    29821 caaattgata tatacatata tctgtgcaat cgccaactat aattatatta tctatattat
    29881 caaaatccaa attttctaat gcaaaaaaac cattagtaga atttttagga agaatttgta
    29941 ggttttctat cgacttaagt tcatcaacca attcactttc tacatcattt tccaaacagt
    30001 gaacaggata actcaaaagt tctattgatt taggagtatg agaatcagta aatgctatta
    30061 ctttatttaa tttgtttgat attttttttg taaacatttc aattggcttt attaaagact
    30121 ctactctagg agagtataat gcaccttgtc ttgcaaagcc attattaaca tcaattataa
    30181 ataaagcagt tttactcaaa tcataatttt ctattttttc tattggtaga ttatctaaat
    30241 tactctttaa agcttcaagt tcatttaata agttatccat agttatacct ccaagataaa
    30301 tttaataaaa ttgtacatat taattatata aaagtcaagg agtacaaact attgtataat
    30361 tagctgtatt gttttgagtg taaaagattt gaagcaatat ctggatagtt agtaaaaata
    30421 ccatctacat tgagttttag acagtgtagt atatcatcct cttcatttac agtatataca
    30481 ttgacaccaa gtagattttt gtgacaaagt tcaattagag attcatttac taaaactaga
    30541 ggtggatgaa ggtaactatt acccagaaat ttagcaaaat tgactacatt gtttataggt
    30601 aaataacaca ataatcctgt ttttatacta gggtctaatt tatgaaagtt ttttaagcta
    30661 ttgctgttga aactagatat aagaactcta tttttcatat tatactttaa aataagctct
    30721 aaaacgtctt tttctatatt gggatagttt attttgtcag tttttagttc tatatttaaa
    30781 ataaggtctg taggtgaaat tagaattaat acttcttcta aagttggaat tttacattct
    30841 ttattgcttt gatatccttc aaaagatgag tttagagttt ttaattttct taaagtaaag
    30901 tcttttacaa aaccatgtcc attaaaagtt ctatcaacct tttcatcatg aataactaca
    30961 atttttccat ccttagttct gtggacatca agttctattc catatatatc catatccaaa
    31021 cattttttaa aagctagaat agtattttct ggatactttc cactaaaccc cctatgagca
    31081 taaatattca tttatatggt tccctcctat aagtataact tatcttataa aaatttaatt
    31141 aatataatat a
//
LOCUS       DAFAZV010000050        29435 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFAZV010000050 DAFAZV010000000
VERSION     DAFAZV010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29435
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.050"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(45..992)
                     /locus_tag="KOU88_003122"
     CDS             complement(45..992)
                     /locus_tag="KOU88_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212978.1"
                     /translation="MRITKTTFNDVFSNDANGSIIKVEKYVDKKCASVFEILTYTIIV
                     TNTSRYKTGNIFFKDYISKYIEFINNTVKVNGIIKRGLDPQQGFYIGRIDASCKKIIS
                     FKSVVLPNSAHRIIKNSANIYYYYKCNLDKFPTRISIESNRVYTNVNKIVFKQLNISN
                     TLKAPKNLRDILKVNVNSKIFDVKPMKNLINKGSNLKLCNLIVFGYIEVEIDYSCKNR
                     SNFKTVNKSNDIKKDKYYKNDIQNNNENINDCKKQISFGDNKVKKITKTFGFSCFICS
                     PVGIIYEDMKNINIKIEHTSINELNPEELFVNTSLLLYY"
     gene            complement(1020..1511)
                     /locus_tag="KOU88_003123"
     CDS             complement(1020..1511)
                     /locus_tag="KOU88_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212979.1"
                     /translation="MYENNKVIYNLERCEKLEKTLYLSQFNTYKNFKLASKKTVINSL
                     ETYVYNMNINNISLVDTIECISLEDEQLTGKKLILVGDIDIDAILDYAGNKRNRNSSK
                     KNTFKLKIPFSTFIQMPRKIENKDKINLKYLIQDITSSILDDNLFISVTAIISYENSS
                     KIE"
     gene            complement(1954..2847)
                     /locus_tag="KOU88_003124"
     CDS             complement(1954..2847)
                     /locus_tag="KOU88_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBK3212980.1"
                     /translation="MKNKKFIVIILIISILIGVLVKEYSSREIKKDDINVSKYIKYAD
                     LASKNNAQVNWKYVASIVAVLNKNNLKNVKDSQIQEVSDLFVKNFSKNNKINKLSDIL
                     DELEFSNRQKRLVDNYIDNLKDYGIKPERLKSDTKYMKFIDEIKTEAIQNYKDYKILP
                     SITIAQAIIESSWGKSTLAKQYNNLFGIKADAYWKGKSVTLETKEHLDTIIDDKFRIY
                     DDKNESIKDHAKFLATNKRYKNNGVFDAKTYIYQAKALEKAGYSTAKDENGNSIYAAR
                     LIELIQQYNLQLIDSEIQSEM"
     gene            complement(3072..5357)
                     /locus_tag="KOU88_003125"
     CDS             complement(3072..5357)
                     /locus_tag="KOU88_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBK3212981.1"
                     /translation="MKCLFSNVDEWKIIQDKIEIKENRLAESIMSIGNGYMGMRGNYE
                     ENYSGDTHKGSYIAGVWFPDKTRVGWWKNGYPEYFGKIPNSVNYIGVRIFIDDVELDL
                     AKCKVEDFHRELDMKNGILNRRFIVNINDKKFEVRVTRFLSISVKELAVIKYSIKSLN
                     SNTKIKFVPYLDSNIKNEDSNYEEKFWNGISSSSLEYKGSILSRTKENAFNTPVFTVG
                     SMMYIKTNGDVEAVSHESDYNYCENSITMDVLKNEVASIEKYVSITSTRDYKESELLR
                     KCEDILNRELSKSYDDILNEHIKLWNKRWESADVKINGDKSSQQGIRYNLFQLFSTYY
                     GEDSRLNIGPKGFTGEKYGGATYWDTEAFCVPVYLGVADKEVTRNLLEYRYNQLEQAK
                     DNAKKLGLKGALYPMVTFDGVECHNEWEITFEEIHRNGSIVYAIYNYTNYTGDYKYIK
                     EKGIDVIIEIARFWASRVHLSTKKDLYMIHGVTGPNEYENNINNNWYTNYIAKWCLDY
                     AVENILRLEKECNECIDRNNVTREEVEFWKIISNKMYLLYDEELQIIIQNDNFLDKEF
                     VEVKDLPKENFPLNQNWSWDKILRSCFIKQADVLQGIYYFGNRFTKEEKKRNFDFYEK
                     YTVHESSLSSSIYSIIASEIDNLEKAYELYSRTARLDLDNYNNDTNDGLHITSMSGSW
                     LSIVHGFAGMRTWNETLSFDPKLPKEWKNYSFNINYRDNIINVDVCSDLIKIENLKGK
                     PIKIIVYGKKYILEKCIKIDK"
     gene            complement(5354..6034)
                     /gene="pgmB"
                     /locus_tag="KOU88_003126"
     CDS             complement(5354..6034)
                     /gene="pgmB"
                     /locus_tag="KOU88_003126"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBK3212982.1"
                     /translation="MIEAFIFDLDGVITDTAYYHYMAWRKLAHKVGIDIDTKFNESLK
                     GISRMESLDRILEFGNKKYSFSEEEKVRMAEEKNNYYVSLIDEITSNDILPGIESLLI
                     DVKSNNIKIGLSSASKNAINVLNHLGISDKFDFIADAGKCKNNKPHPEIFLMSAKGLN
                     VNPQNCIGIEDASAGIDAINSANMFSVGVGNYENLKKANLVVDSTNQLKFEYIQEKYN
                     EYIVRRII"
     gene            complement(6258..8141)
                     /locus_tag="KOU88_003127"
     CDS             complement(6258..8141)
                     /locus_tag="KOU88_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBK3212983.1"
                     /translation="MSNKNKENITLSNQIKGTIQNSLTKEAILHIPMSNYAYGYDRET
                     LHIRLRTKKNEAKRVILRIGDQYVWDKGGAGGGNLNASGVGWSGGTNIVMSKEVETEL
                     FDYWIAKCKPLNKRSRYGFIIEGQEEKLLFTEKRIIELGNENDEKELCEIGNFFGYPY
                     LNYIDIPKVPNWVKDTVWYQIFPDRFANGDPSINPEGVDKWGAIPTRDNFTGGDLQGV
                     IEHLDYLSDLGINGIYFCPITIGKTNHRYDTVDYMEVDPTLGDKETLKKLIEEAHKRN
                     IKIMLDAVFNHIGYYSKQWQDVVQNKENSRYKNWFYIKDMSKIDTPIEQIDEKNIPYE
                     TFGCEKYMPKLNTENSEVIKYLLDVGKYWIQEFDIDAWRLDVSNEVDHVFWRKFREEV
                     KKVKPDIYILGEIWHGSLPWLMGDQFDSVMNYLMSEAMKKFFCTDEINAEEFKYMIND
                     VMVSYPIQVSEVIFNLLGSHDTTRILTYANGNIDRFKLAYMFMFVQTGCPCIYYGDEI
                     GMEGELSSISEGQRKCMEWNEEKWNKDIFDFMKKIIRLRKENKELRSISNEWVLADKE
                     NGTIILKKESISIIINNSSKNIILTLPDYLANKKVKDLYEEEIVDLKEELMLEKYKFI
                     ILK"
     gene            complement(8399..9220)
                     /locus_tag="KOU88_003128"
     CDS             complement(8399..9220)
                     /locus_tag="KOU88_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase HisJ family protein"
                     /protein_id="HBK3212984.1"
                     /translation="MNLIDNHIHTNFSSDGKDSMEDTIKKAISIGVRYLTFTDHLEHD
                     EDRGFCINYNDYVPVFNKFKEKYKKDIELLLGVEVGYRKHLKNEIEEIINSNPFDFVL
                     CSTHTIDNVPVPSKAYFKGLSKEDAYYKYFNSILETNREFGDYNIYGHLDYISRYGIY
                     SDNRVIYNDFKDVIDEVLKSIINNGSGIELNTSGYRYGLNAIHPNEDILKRYKELGGF
                     IVTVGSDSHRVEDICKDFDVAYDMLKYLDFKYVSLFKERETYFVNIEKVKSNNIA"
     gene            complement(9411..9764)
                     /locus_tag="KOU88_003129"
     CDS             complement(9411..9764)
                     /locus_tag="KOU88_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3212985.1"
                     /translation="MKKSNIFSIIFPTVIMVLMFLTFATDIFNIPDIQSKSIFVVGMV
                     LIFPISFLIQGIICVLNKTNWILSLIVSLVTYIVLMYIFLNDSAYIYVLLYTAFYMIG
                     HITAKLYYKIKTFKN"
     gene            complement(9806..11248)
                     /locus_tag="KOU88_003130"
     CDS             complement(9806..11248)
                     /locus_tag="KOU88_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBK3212986.1"
                     /translation="MRTIRRVLALGLTLAIFLINVPNVDALTSDTIKGNNIYETAGLI
                     ADKKSYDTAIMVNMDNSIADGLSASGLAGAVDAPILLAQKNKIPNETKQRLKNVKKIY
                     IIGKELSISKSVETELKNTGAQVTRLGGDDRIKTSYSVAKEVNGIKKVDEVILTNAYK
                     GEADTISAAPVSVRDIAPIVLTDGKSVPFSTSNVKTYAVGGSISMSTSLVNKTNAKRL
                     GGSDRYDTNKKVIKEFYPDASEFYLSDGYDLVNALTGSTIAKENPIVLVSESSDKSIL
                     AGADKITRLGSISDSVYNKCVSAAQNNGDSSTKGESPMKNETSILGQPTASLEACLKW
                     AKSKKANDLFIELIPILYDTAVQEGVNPVLAVAQSAKETGFCNFGGVLDASFKNPCGL
                     KTSVGGSDTDKNAHSRFDTWEEGILAQIQHLCLYAGQDGYPLSNPVDPRHEKSLFGKA
                     KTVESLSNNWAGGQYGQDLVRMMGEIEATK"
     gene            11924..13135
                     /locus_tag="KOU88_003131"
     CDS             11924..13135
                     /locus_tag="KOU88_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HBK3212987.1"
                     /translation="MSNKQGSNIKDVKIKNKLIILKLLSTNTPMSRVDLAKSTGLTKM
                     TLSNLVTELINENMIREIESSTLNAHSSGRKPILLDISNISPCICGILIRRNICKVII
                     SDLKGNIVKQLSETYPKFLSNDVLKDIIKRMFTKIMKINKRDIIGIGISSIGPVDDIN
                     GTILNPPDFGNVSNLNIVDFIKEMSDLPIFLINDANSGALAEKMYGLGKNISNYIYLH
                     IMNGIGAGLVLENKLHTGNLGQSGEIGHTSINFSGPLCSCGNNGCLDYYTSVSNLIKR
                     IESLSHIYPNSPLINCKDFSLVKLIDEANNKDSLAMFLLDEFCTYVSYALVNTLTLID
                     CSSIIIGYDFNIPGTFIENTLLKKLTASASFSKYKKISVRHSNFGANAPLIGSIAIVS
                     YNFFNGSINFY"
     gene            13227..13742
                     /locus_tag="KOU88_003132"
     CDS             13227..13742
                     /locus_tag="KOU88_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin"
                     /protein_id="HBK3212988.1"
                     /translation="MISAKMEKLLNEQINHELYSAYLYLSMSSYLEAEGLKGFSNWFY
                     VQYKEETDHAMFFYKYLHNVGGKVQLDAIPMPDSDFTSAMDILERTLAHEKKVTALIN
                     NLAAVANSESDFRTSQFLLWFISEQAEEETNCEDNIKRVKLAGEGGLFFVDQEFANRT
                     YAAPTNPPVTI"
     gene            complement(14009..16108)
                     /locus_tag="KOU88_003133"
     CDS             complement(14009..16108)
                     /locus_tag="KOU88_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase family protein"
                     /protein_id="HBK3212989.1"
                     /translation="MSLEKLIRPKSIAIVGVTDKLGFGRSAALSIVKSKETDRVYYVN
                     PKREELFGRKCYKTIQEVPEVVDCVVVCTPRNVVPSVLKDSGELGTKAAVVYASGFAE
                     EGTEEGTDLENQLIEISNTYDMKILGPNCMGLLNCIDKVNLWAGGSKWDLDTKKPGIG
                     IVGQSGFITAEIVSSDYFNISYGFSTGNGNIVTLEDAVDFLVDDDYASVIAIYLEGLK
                     NPQKFIDALKRAAQKRKPVIILKSGRSEKGAISAASHTGNLAGSSKAFESIFEKYGVI
                     SVENLEQFMCLAQAFSVLDGNLPANSNFAAINFSGGENTICADLAEENGVELAEISSE
                     TKEEMEKYLPGFATPKNPLDATTALFHEKDMIVGLLHTFEKDDSVGFTMVGANIRDEE
                     NEMHETLCKAVSEAREQGLKKPVFAVPTLEGNRYLDYRTRLEDNQVPIMSSVGTTFTC
                     FNKMAKFIDYDYSKRTLEFKAVKKRESNNVVALSELDSKIEMKKYGVPVPGQGNAKSI
                     DELDEILKYIKYPVVLKINSSEILHKSDVGGVKIGIKNRDEAVDAYNEILTNVKKAKP
                     DANIDGILVQEMVESGIEIIIGITNDDQFGPMLLVGLGGVFVEVFKDTTLYPLPINHD
                     EAIMMLKKLKSFKLLNGYRGSEPCDIDALADMMVKLGKYAYENKDEVKEIDLNPVFVY
                     PKGKGVCAVDALIVKYK"
     gene            complement(16232..16771)
                     /locus_tag="KOU88_003134"
     CDS             complement(16232..16771)
                     /locus_tag="KOU88_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase family
                     protein"
                     /protein_id="HBK3212990.1"
                     /translation="MEKELVFAGFGGQGVLTLGLIVAESALELGKQVTWMPAYGPTMR
                     GGKAYSVVKFSDESIGGPDMEEIDVLVAMNKPSLDYINLVKEGGTVVINTSAIDENVT
                     LREDISVVKINCQELAQKVNNPKAANIVVLGALIAKTGLFEKELALKTMCDFFEEKGK
                     GKFNVQNEAAFMEGYNNAI"
     gene            complement(16774..17514)
                     /locus_tag="KOU88_003135"
     CDS             complement(16774..17514)
                     /locus_tag="KOU88_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate oxidoreductase"
                     /protein_id="HBK3212991.1"
                     /translation="MATEKLTPSVVSIPNKFCPGCGHGIVNRIIAEVIEEHGYEKNHV
                     LTLGVGCVCNMNFSWNGDKMQTAHGRASSTAIGVKVALPDTLVMTYQGDGDAYVIGLS
                     ETLNTAYRNHNVTVFVINNNNFAMTGGQMSWTTMPGQVTTTSVNGRDIKTTGSPLKVP
                     EMVANFFDVAYVARGSVHSPKEIINLKKYIKNAIEAQLNGEGYSLVEILAPCPTNWGV
                     SLEKSIKWMEEEIVPYYALGEFKQRDGE"
     gene            complement(17516..18565)
                     /gene="vorB"
                     /locus_tag="KOU88_003136"
     CDS             complement(17516..18565)
                     /gene="vorB"
                     /locus_tag="KOU88_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate dehydrogenase subunit
                     VorB"
                     /protein_id="HBK3212992.1"
                     /translation="MKKMWKGNHAIAEAALRGGCEFYAGYPITPQTEVMEFLSHRMSE
                     LGRTFIQSENEMAAIYMVYGAYASGMRSMTSSSGPGISLKQEGISYLCANHYPCVIVN
                     VQRWGPGLGSLDSAQTDYLRDTRGGGNGDYHLIVYAPNSIQETVDLMYNSFDVAEKYR
                     VPVEILTEAALGQMMEPVEFPEFKKREGDLGWTYDGSNRDHAKVADNQKPTFCMEKRM
                     RITENEQQWEDYQVEDAEYVFVAFGIPSRTTMNAVRRLREQGEKVGIIRPITVWPFPY
                     KAFEKVSKDVKGFISVESTDTGQLVEDVALASKKVCKENVPVYGLFSGNHIPKTLQVM
                     DTYSKIKSGEIKEVF"
     gene            complement(18582..18818)
                     /locus_tag="KOU88_003137"
     CDS             complement(18582..18818)
                     /locus_tag="KOU88_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3212993.1"
                     /translation="MKRGVDMNLKINAERCKSCEYCVISCKKGALKISSKINKEGYAH
                     VEVDESKCILCGICYQVCPDNVFEIIKEEACQEA"
     gene            complement(18833..19936)
                     /locus_tag="KOU88_003138"
     CDS             complement(18833..19936)
                     /locus_tag="KOU88_003138"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBK3212994.1"
                     /translation="MIEKLLRNTVKELHQYVPGEPIEKVKEKYGVKEIIKLASNENPL
                     GPSPKAIEAMIEMLKQGQLYPEPEANELRRKLAEKLDLKPENFIVANGADNVITLIGE
                     AFINRGDEVIYCNPTFPSYRTATIKNEGIPVEVPLTEDYKYDLQGILDKITDKTKLIC
                     VCNPNNPTGTIVDDKELEEFLKKVPENIITILDEAYIEFLTVPNYVDGLKYVRENYNV
                     IVTRTFSKIYGLAGLRVGYGIAKDEIIRTLFTVKEPFSANRVAISGATAALDDEEFIK
                     ETYELNRVGMAYFKEEFTKMGFDVVDSQSNFLYVDMKTDIPKLFEDLKKRGFVIRPSA
                     THARVSIGTMEENRKFVAVLKEILNIKGEPSIG"
     gene            complement(20039..21469)
                     /locus_tag="KOU88_003139"
     CDS             complement(20039..21469)
                     /locus_tag="KOU88_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3212995.1"
                     /translation="MSSQESKPKGNLISNFRDDMRDPKKRAIYTYSSSINLAYNFIGY
                     FVSTVTNIFLTDVAKLGVIMAGGMQIIQSFIKIAVAPITGTVFDKQPFKKGKYYPWLR
                     YAPAALALTYGIFFIVPLMKISPALLLPLMTALLLIASCAQQVVFTIIYAIYPVVAKT
                     PRDRVIGSTTTNIFKEVGKFLVGFSYPLLLVLFADVLGGEGMGYLGTYLFFAAGCLLV
                     FWFSSTEIIKSGAEEEVLQKEEKPKIKASEMAKALFTNVPLMMAFCLEFLICIRSIGL
                     GPLAPYYFKYVIEDERGLAVFLSIMPLVSVAFMFFAPVFIKICREQKLASIISFSICA
                     LCHLLVAWTPWGKTTLGVTMLLAIGGGFSNVVSIINLNFFAGSCDYGHWKSGKDLPGL
                     SMSLYPVAIQVGVLLATTIRTVLMNSMGYQADMVVTEAVKSGFINMISYSMAIPLIIA
                     VVIAILYPVSDKKLNQIREELNQRNA"
     gene            22127..23491
                     /locus_tag="KOU88_003140"
     CDS             22127..23491
                     /locus_tag="KOU88_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter family protein"
                     /protein_id="HBK3212996.1"
                     /translation="MLLLIVTCAIYIWIGFYFSKKVKTASDFLIAGRNLPLPILAATI
                     AATSFGGGCLVGGVQWGAERGLWVGMYSTIGAALACFINAFFAGKLRSLSCDITPADY
                     IETRYGHSVFLRAYQSLVTPISILAIMGSQLISFGSVSTAFGIPYDIAVIIGVIVIII
                     YTYTSGMWGVAVSAFIQLAICIVFLPIVAYISLKLVGDNPLLMLQSMVKEPFFPGNKS
                     ISDFMYTVLPLVLGSIFSYESFLRYQCADNAKNAVKSSVIAGFILLFLAFPIGIIGAI
                     GGSLFPNISSVQVLPQMISTTLPPLISVLFLAAILAAIMSTADSLMTSMSAIISRDIY
                     NKLLHPNIEFNDLKNTLKYSQIASALTAIIGAIIALKFDSLLELLFWPAPLCTGVIFA
                     PFVIGLCWKGATKKGAIYAVIVSVILALLNMIGILTVFDRILVPIIGGSITIFIVSKF
                     SKKD"
     gene            23515..24168
                     /locus_tag="KOU88_003141"
     CDS             23515..24168
                     /locus_tag="KOU88_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3212997.1"
                     /translation="MSKSEKGKETKASIISAARELFFEQGYHKTTTRQIAERANINLG
                     LISYYFSSKSEIGAIIYEDIRNEMQSLIYNYHEEGTMMMFFLAMNADLCFLLKNEAYR
                     NFYLDIAYEEAILSYQRSVTEMVMKRYVNDKESIEHDELILSCIGILAMKPEIIRVYT
                     SHKYDISSQAVIKHFTKQFLINLGHSTDLCEEILEELSKYYIDIVDNFTPIITRVRT"
     gene            complement(24287..25069)
                     /locus_tag="KOU88_003142"
     CDS             complement(24287..25069)
                     /locus_tag="KOU88_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBK3212998.1"
                     /translation="MAFIECKFKSKYTGGETDIIVILPVANGKELFSGKEIYDFEGKF
                     KTLYLFHGLEDDQSSWIRYTNVEHYAKNKNIALVIPRVETSFYTDMAYGHQYFTFVSE
                     ELPKFVRAIFPLSDKREDNFVAGMSMGGYGALKLALSKPKEFSAVASFSGSPDMIHEL
                     ENQQIETNADILFHDFGRPEDARNSENDLLYILKNLKERNEDIPKIYQFCGDRDFLYK
                     NNQMFKKYADSLGVDVEYEECVGGHEWRLWNLWIKKFIDIIG"
     gene            complement(25186..26352)
                     /locus_tag="KOU88_003143"
     CDS             complement(25186..26352)
                     /locus_tag="KOU88_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK3212999.1"
                     /translation="MKINWNTKYTTIAIYTFIIAASSIIFYLVSSQIDVFSNNLDAIF
                     TTLQPFIIGFAIAYLLNFILKFYEDRIFIKSEKLKKLKQSSKRGLGLLLTYATATLIL
                     YLFMHFVLPQVIESIVGLANDIPMYVNNATKLIDKLMTDLNLDEQYFNLAVDKWNEFV
                     TYIIKFVTDLIPILGSMLKNVASSIWNIVLGLIVSVYLLIDKEKFYGLSKKITYAVFT
                     EKQAARILELTHRSNYTFGRFLGGKILDSFIIGILTFVILTLVKMPYTLLISVIIGIT
                     NIIPFFGPLFGAIPSTLIVMFVSPIKAFWLLLIILIIQQIDGNIIGPKILGDSIGISA
                     FWILFSLLVAGKLLGFIGMVIGVPMFAVIYSIIKDIVESKLDKKGLPTDTSDYM"
     gene            complement(26491..27855)
                     /locus_tag="KOU88_003144"
     CDS             complement(26491..27855)
                     /locus_tag="KOU88_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBK3213000.1"
                     /translation="MDIKELVKMQRKYYNTGKTRDISFRIEQLKKLKLVVSQNEEKIL
                     LALKKDLNKSDFEGFMTEVGMFYSELNFAIKNIRKWSKIKRVKSSMVNFPSISKVVPQ
                     PYGVTLIMSPWNYPFQLALIPLVWSLAAGNCVILKPSEYSVSTSSVVKDIVEDTFSKE
                     YVAVVQGSQEESEKLLLERFDYIFFTGSTNVGKIIMKSASEHLTPITLELGGKSPCII
                     LKDANIDLTAKRLTWGKLINAGQTCVAPDYVLVHEDRKNELIEKIKYYTNKYFGDNAC
                     NNEQFPKIINQRHFNRILSLIDKDKIVYGGNYNKETLKIEPTIVDNVNWDDNIMKEEI
                     FGPIFPILTYKDLDEVIQKIIQMPNPLALYIFTKNKYLENKLLEMIPAGGCCINDTVT
                     HIATNYLPFGGIGESGMGSYHGKAGFDTFTHYKSVLKKLNLDVPIRYAPYDNKLIKVL
                     KKIM"
     gene            complement(28167..28691)
                     /locus_tag="KOU88_003145"
     CDS             complement(28167..28691)
                     /locus_tag="KOU88_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBK3213001.1"
                     /translation="MKSVVVIYKSKYGSTKKYAKWLSELLSCDIFETKNINIEKVMKY
                     DTIILGGGLYACNIAGISFLKKNYKELQKKNLVVFGVGAAPYDDEVIKKLREVNFKDE
                     LNKIPCFYCRGAWDETKMSFIDYTLCSFFKKSIAKKERQGLKPAEAPLLSGEAFDWCN
                     KENLTPILDYIREL"
     gene            complement(28740..29237)
                     /locus_tag="KOU88_003146"
     CDS             complement(28740..29237)
                     /locus_tag="KOU88_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3213002.1"
                     /translation="MDAESLMKKYMVDDDSRKQAIFASIFVMQNKLQTTCDKLDPELT
                     MKQWLLLAIADSVDETLTLTKLGELMGCSRQNVKKLAIALEKKGFIEIEQNEKDSRAI
                     CLVTKDRVEEYSKKVRGMQEKVLQLLFEDFTEKEAEQLFFGIMKLSIGIENVKNYVEN
                     NDVGE"
BASE COUNT         9648 a         5020 c         3198 g        11569 t
ORIGIN      
        1 accaaatgct attttaataa gtttaagttt tagctttaaa atacttaata atacaataaa
       61 agtgatgtat ttacaaataa ttcttctgga tttaattcat ttattgatgt atgttcaatt
      121 tttatattta tatttttcat atcttcataa ataattccaa ctggagaaca aatgaaacaa
      181 gaaaatccaa aagtttttgt tatttttttt accttattat caccaaaact tatttgcttt
      241 ttacaatcgt ttatattttc attgttattt tgtatatcat ttttataata cttatctttt
      301 ttaatgtcat tagacttatt tactgtttta aaattactcc tatttttaca actatagtct
      361 atttcaactt ctatataccc aaaaactatc aagttacata atttcaaatt actacctttg
      421 tttataagat ttttcatagg tttaacatca aatattttac tatttacatt tacttttaat
      481 atatctctta gatttttagg agcttttaaa gtattactta tattcaattg tttgaataca
      541 attttattta cattagtata aactctatta ctttctattg atattcttgt tgggaattta
      601 tctagattac acttataata atagtatata ttagcactat tctttataat cctatgtgca
      661 gaatttggta aaactacact cttaaaagat attatttttt tacaacttgc atctattctc
      721 cctatgtaaa aaccttgctg tgggtctaat ccacgtttta taatgccatt aacttttacc
      781 gtattattta taaactctat atatttagaa atataatctt tgaaaaatat atttccagtt
      841 ttgtacctac ttgtatttgt aacaataata gtgtaggtca aaatctcaaa tacagatgca
      901 cattttttat caacatattt ttctactttt ataatacttc catttgcatc atttgaaaat
      961 acatcattaa aagtagtttt cgttattctc attgcatcca cctttctata atttaaagat
     1021 tactctatct tggaactatt ttcataactt ataattgcag taacactaat aaataaatta
     1081 tcatctaaaa tagatgaagt aatatcttgt ataagatact ttaaattaat tttatcttta
     1141 ttttctatct ttctaggcat ttgtataaat gtactaaagg gtatttttaa tttaaatgta
     1201 ttttttttac tagaatttct atttctttta ttgcctgcat aatctaatat tgcatcaata
     1261 tctatatcac caactaaaat caacttcttt cctgtaagtt gttcatcttc taatgatata
     1321 cattctatag tatcaacaag acttatattg ttaatattca tattgtaaac atatgtctct
     1381 aatgaattta ttacagtttt tttagaagct aatttaaaat ttttatatgt attaaattga
     1441 gataaataaa gagtcttttc tagtttttca catctttcaa ggttgtatat taccttatta
     1501 ttttcataca taatcgcatc aatctccctg tatctatata ttaatactat tcataaaaat
     1561 tatttcaaat taccattttt tattattcac tatctagttg ttatttactt ttaagaaaga
     1621 atcctttttt acttcattga tttcaattta caagtaaaag tctttctgaa aaaaaaatat
     1681 atatatctct attcactttt ttataagtaa ttataatttt tatagactaa cggtcagcct
     1741 taagggaaaa ggtgttcttt aagtgcagaa tttagataaa gtaaataatc cttttataaa
     1801 taattccaag ttttaactta aataatttga tttacagtat aaagtaaatt ttgaaagata
     1861 atgatatcga tttaataatt acaagtaaaa gcatgtcaaa ataaggctat gattttaaaa
     1921 atcatagcct tatcaataaa aatttaatca aagttacatt tcactttgaa tttcactgtc
     1981 tattaattga agattatact gttgaattaa ttctattaga cgagctgcat atatactatt
     2041 gccattttca tccttcgcag tactataacc tgccttttct aatgctttag cttgatatat
     2101 atacgttttt gcatcaaata caccattgtt tttatacctt ttatttgtgg ctaaaaattt
     2161 tgcatggtct tttatagatt catttttatc atcatatatt ctaaatttat catctataat
     2221 tgtatctaaa tgttctttcg tttctaaagt cactgacttg cctttccaat aagcgtcagc
     2281 ctttatacca aatagattgt tatattgttt tgccaaagtt gacttgcccc agctagattc
     2341 tattatagct tgtgcaatag ttatagatgg aagtatttta taatccttat aattttgtat
     2401 tgcttctgtt ttaatttcat caataaactt catatatttt gtatcagact tcaatctttc
     2461 tggttttata ccataatcct taagattgtc tatataatta tcaaccaatc ttttttgtct
     2521 attactaaat tctaactcat ccaaaatatc acttaactta tttattttat tatttttaga
     2581 aaaattctta acaaataaat ctgatacttc ttgtatctgt gaatccttaa cgttttttaa
     2641 gttattttta tttaacacag caacaatgga agctacatac ttccagttaa cttgtgcatt
     2701 atttttactt gctaaatcag catattttat atacttactg acatttatat catccttttt
     2761 tatctctcta gatgaatatt ccttcactaa tacacctatt aaaattgata ttatcagtat
     2821 tataacaatg aattttttat tcttcataaa tattgtcctc ccttatacta tctgctgaat
     2881 ataatatacc ttacttttgt gacatattct ttacgaaatt ttgaaaattt tatgaagatt
     2941 tatgaaatat atttaattaa aagcactact attgttataa tatatagttt tctatcacac
     3001 aaaatagtta aaataaataa ataattagat agcttatttt aactatttat ataataaaaa
     3061 tattattaaa tctatttatc aatttttata catttttcta atatatattt tttcccatat
     3121 acaataattt ttattggttt accttttaaa ttttctattt taattaaatc actacataca
     3181 tctacattaa taatattatc tctataattt atattgaaag aataattttt ccactctttt
     3241 ggcaacttag ggtcaaaaga tagagtttca ttccatgttc tcatgcctgc aaatccatgt
     3301 acaatggaaa gccatgaacc agacattgaa gttatgtgca gtccatcatt tgtatcatta
     3361 ttgtaattat ctaaatcaag cctagctgtt cttgaatata attcataagc cttttctagg
     3421 ttatctattt ctgaggcaat aatagaataa atactagaag ataaagaaga ttcatgtaca
     3481 gtatattttt catagaagtc aaaatttctc tttttttctt ctttagtaaa tctatttcca
     3541 aaatagtaaa ttccctgtaa tacatctgct tgttttataa aacacgacct aagaatctta
     3601 tcccaagacc aattttgatt aagaggaaaa ttttcttttg gtaaatcctt tacttctaca
     3661 aattctttat ctaaaaaatt atcattttga attattattt gtagttcctc atcatacagc
     3721 agatacattt tatttgatat tattttccaa aactcaactt cttccctagt cacattattt
     3781 ctgtcaatac attcattaca ctctttctct aatcgtaaga tattttctac agcataatct
     3841 aaacaccatt tagctatata attagtatac caattattat tgatattgtt ttcatactcg
     3901 tttggacctg ttactccatg tatcatatac aaatcttttt ttgtagacaa atgaactcta
     3961 cttgcccaaa atctagctat ttctattatt acatctattc ctttttcttt tatatattta
     4021 tagtcacctg tataatttgt atagttatat attgcatata ctatacttcc atttcggtgg
     4081 atttcctcaa atgttatctc ccattcatta tgacattcta ctccatcaaa tgttaccatt
     4141 ggatataaag cacctttaag acctagtttt tttgcattat cctttgcctg ttctaactga
     4201 ttgtacctat attctaaaag atttctagtt acctccttat ctgctacacc tagatatact
     4261 ggaacacaaa atgcttctgt atcccaataa gtagctcctc catacttttc accagtaaat
     4321 ccttttggac ctatatttaa tcgcgaatct tctccataat atgttgaaaa tagttggaat
     4381 aaattatatc ttataccttg ttggctactt ttatctccat ttatttttac atctgcactt
     4441 tcccatcttt tattccataa ctttatatgt tcatttaata tatcatcata acttttagat
     4501 agttctctat ttaaaatgtc ttcacatttt cttaatagct cactttcctt ataatctcta
     4561 gttgaggtta tagatacata tttttctata cttgcaacct cattttttaa aacatccatt
     4621 gttatcgaat tttcacagta attataatca ctctcatgag atacagcttc tacatcacca
     4681 tttgtcttaa tatacatcat tgaacccaca gtgaatactg gtgtattaaa tgcattctcc
     4741 tttgttcgag aaagaatact ccctttatat tctaaagaac ttgaagaaat tccattccaa
     4801 aacttttcct catagtttga atcttcattt tttatatttg aatctaaata tggtacaaat
     4861 tttattttag tattagaatt taatgatttt atactgtatt taattactgc aagttcctta
     4921 acagatatac ttaaaaacct agtaacccta acttcaaatt ttttatcatt tatatttaca
     4981 ataaacctac gatttaaaat accatttttc atatctaatt ctctatgaaa atcttctact
     5041 ttacattttg ctaaatctaa ttctacatca tctatgaaaa ttcttacacc tatatagttg
     5101 actgaattag gaattttacc aaagtattct ggatacccat ttttccacca accaacacga
     5161 gttttatctg gaaaccatac tccagctata taagacccct tgtgtgtatc tccactataa
     5221 ttttcctcat agtttcctct catacccata tatccattgc ctatactcat tatggactct
     5281 gctaatctat tttctttgat ttcaatctta tcttgtataa tcttccactc atctacatta
     5341 ctaaataaac atttcatata attctcctaa ctatatactc attatacttt tcttgtatat
     5401 attcaaactt taattgattt gttgaatcta caactaaatt tgcttttttt aagttttcat
     5461 aatttccaac accaacagaa aacatattag ctgagtttat agcgtctata cctgcacttg
     5521 catcctctat ccctatgcaa ttttgtggat ttacattaag ccctttcgct gacataagaa
     5581 atatctctgg atgtggttta ttgtttttac attttcctgc atcagctata aaatcaaatt
     5641 tgtcacttat acccaaatga tttaatacat ttattgcatt cttacttgca gaagatagac
     5701 ctatctttat attattagat tttacatcaa ttaacaagct ttctatgcct ggcaaaatat
     5761 catttgaagt tatctcatct atcaatgata catagtaatt atttttttct tcagccattc
     5821 tcactttttc ttcttctgaa aatgaatatt tcttatttcc aaattctaat atcctgtcca
     5881 atgactccat tctacttatg ccttttaaag attcattaaa ttttgtgtct atatctatcc
     5941 caactttatg agctagtttt ctccaagcca tatagtgata atatgcagta tctgtaatta
     6001 caccatctaa atcaaatata aatgcttcaa tcattcttat ttcctctttc tacaagaaat
     6061 ttttagacta ataatcaatt tattttctat cttgtattta agatattatt tataaaatta
     6121 tctactctaa ctcagtcttt aatttaaaat ctactttcaa ttcactcact tgtagaccat
     6181 attttttatc gtttataaag acttgtttaa actgtataat aatttaacat gaaatctaaa
     6241 ataaatactt ttttgtatta ttttaaaata atgaacttgt atttctctaa cattagttct
     6301 tcttttaaat caactatttc ttcttcatat aaatctttta cttttttatt tgctaaataa
     6361 tctggtaacg tcaaaattat atttttagat gaattattta ttattataga aatagattct
     6421 tttttcaata taatcgttcc attttcctta tctgctaaca cccattcatt tgatatagac
     6481 ctaagttctt tattttcttt acgaagtcta ataatcttct tcataaaatc aaatatatcc
     6541 ttattccatt tttcttcatt ccattccata cattttcttt gaccttcaga tattgaactt
     6601 aattctcctt ccattccgat ttcatcacca tagtatatac aaggacatcc tgtttgtaca
     6661 aacataaaca tatatgcaag tttaaatcta tcaatatttc cattagcata agtcaatatt
     6721 cttgtagtat cgtgacttcc aagtaaatta aaaataactt cactaacttg tattggataa
     6781 cttaccatta catcatttat catatactta aattcttcgg cgtttatctc atctgtacaa
     6841 aagaattttt tcatggcttc tgacatcaag taattcataa ctgaatcaaa ttggtcaccc
     6901 attaaccatg gtaaactacc atgccaaatt tctcccaata tataaatgtc tggttttact
     6961 tttttgactt cttctctaaa ctttctccaa aaaacatggt ctacttcatt tgaaacatct
     7021 aatctccacg catctatatc aaattcctgt atccagtact tgcctacatc caataaatat
     7081 tttattactt ctgaattttc tgtattaagt ttaggcatat atttttcaca cccaaaggtt
     7141 tcataaggta tatttttttc atctatttgt tctattggag tatcaatttt actcatatct
     7201 tttatataaa accagttttt atatcgagaa ttttccttat tttgaactac atcttgccac
     7261 tgtttagaat aatatcctat atgattaaaa acagcatcca acattatttt tatatttctc
     7321 ttatgcgctt cttctattag tttttttaaa gtctctttat ctcctaatgt agggtctacc
     7381 tccatataat ctaccgtatc atatctatga ttggtttttc caattgtaat agggcaaaag
     7441 taaattccgt ttattcccaa atcactcaaa taatctaagt gttctatcac accttgtaaa
     7501 tctccacctg taaaattatc tctggttgga atagctcccc atttatctac tccttctggg
     7561 tttatagacg ggtcaccatt tgcaaatcta tctggaaata tctgatacca aacagtatct
     7621 ttcacccaat ttggcacttt aggtatatct atataattta aatatggata tccaaaaaaa
     7681 ttacctattt cacataattc cttttcatca ttttcatttc ccaactctat tattcttttt
     7741 tctgtaaata aaagtttttc ctcttgacct tctattataa agccatatcg tgagcgttta
     7801 tttaaaggct tacacttagc tatccaatag tcaaataatt cagtttctac ttctttactc
     7861 attactatat ttgttccacc agaccaacca actccagatg catttaaatt tcctcctcct
     7921 gcacctcctt tatcccacac atattggtct cctattcgta aaattactct tttcgcttca
     7981 ttttttttag ttctaagtct tatatgtagt gtttctctat cataaccata ggcataattg
     8041 ctcattggta tatgtaatat agcttctttt gttaaactat tttgaattgt tcctttgatt
     8101 tgattactta aagttatatt ttctttattt ttattagaca ttttaaaatt tccctccttt
     8161 ataataattt atataatcta aagataggtt aatatatttt actattatat cacaataaaa
     8221 atatataata gtaaaatata tcaacaataa actattcaat ttaaaataag ctatactatt
     8281 taaatttaat tctatttagt tattttagca aaataaaaac ctctagtatt tttctagagg
     8341 atacaatact ataactatta actttttaac tatctattaa tttacttcaa aacacactct
     8401 aagctatatt gttagattta actttttcta tatttacaaa ataggtttct ctttctttaa
     8461 ataaagatac atatttaaag tcaagatact taagcatatc ataggccaca tcaaaatctt
     8521 tgcatatatc ttctacccta tgagaatcag aacctacagt aactataaat cctccaagtt
     8581 ctttatatct ttttagaata tcttcatttg gatgtatagc atttagtcca tatctataac
     8641 cagaagtatt tagctctata ccactcccat tattgattat tgactttaag acctcatcaa
     8701 taacatcttt aaagtcattg tatataactc tattatctga atatattcca tacctagata
     8761 tataatccaa atgaccatat atattgtaat ctccaaattc acgattagtt tcaagtatgc
     8821 tattaaaata tttataatac gcatcttctt tgctaagacc tttaaaatac gcctttgatg
     8881 gaacaggtac attgtcaatt gtatgagttg agcacaatac aaaatcaaaa ggattagaat
     8941 ttattatttc ttctatttca ttttttagat gttttctgta acccacttca acacctagta
     9001 ataactctat gtccttttta tatttttctt taaacttatt aaatactgga acatagtcat
     9061 tataatttat gcaaaatcct ctatcttcat catgttctaa atggtctgta aaagtcaaat
     9121 atctaacacc aatacttata gcttttttta ttgtatcttc catggaatcc tttccatcac
     9181 ttgaaaaatt agtatgaata tgattatcta ttaaattcat attatccctc cctttatttt
     9241 atctatctta attatacaac aagtttattg tatacatttg ttaaaagaaa attataatgg
     9301 ttaaatttta tttacatact tttattttta caaaaaagag aagcacctat ttctgatttt
     9361 agaaaatcat taaggatact tctcctaatg ttacttttat atacttcaat ttaattttta
     9421 aaagtcttaa ttttgtaata gagtttagct gttatatgtc caatcatata aaaagctgta
     9481 taaagtaaaa catatatata tgcagaatca tttaaaaata tatacattaa tactatataa
     9541 gttactaaag aaacaataag agataaaatc caattagtct tatttaatac acaaattatc
     9601 ccttgtatca aaaaagaaat tggaaaaatc aaaaccattc ccacaacaaa aatactttta
     9661 gattgaatat ctggaatatt aaatatatct gtagcaaaag ttaaaaacat tagcaccatt
     9721 atgactgtag gaaatatgat actaaaaata ttactctttt tcataataat caatccttat
     9781 ttattggata tttgataatc ttcaattatt ttgttgcctc aatttctccc atcattctta
     9841 ctaaatcttg tccatattga cctccagccc aattattaga taaactttca actgttttag
     9901 ccttaccaaa taaagatttt tcatgtctag ggtctactgg atttgaaagt gggtaaccat
     9961 cttgtcctgc atataagcat aaatgttgaa tttgagctaa tattccttct tcccaagtat
    10021 caaatcttga atgggcattc ttatcagtat cagaaccacc tacagaagtt ttaagtccac
    10081 aaggattctt aaatgatgca tctaatactc caccaaaatt acaaaaacca gtttcttttg
    10141 cagattgagc tactgccaaa acaggattaa caccttcctg aacagcagta tcatataata
    10201 ttggtattaa ctctataaat aaatcattag cttttttaga ttttgcccat tttaagcacg
    10261 cttctaaact agctgttggc tgacctaata tgcttgtctc atttttcata ggtgactcac
    10321 cttttgtaga cgaatcgcca ttattttgtg cagcagaaac acacttatta tacacactgt
    10381 cacttattga acctaatcta gtaatcttat ctgctcctgc taatatagac ttatcactac
    10441 tttctgacac caatacaatt ggattttcct tagcaattgt agaacctgta agtgcattta
    10501 ctaaatcata tccatcactc aaataaaatt ctgatgcatc tggataaaac tcttttataa
    10561 ctttcttatt tgtatcatat ctatctgaac caccaagtct tttagcatta gttttattaa
    10621 ctaaactagt gctcattgat atactcccac ctactgcata tgtttttaca ttgcttgttg
    10681 aaaaaggcac actctttcca tctgtaagta ctataggagc tatatctctt actgatacgg
    10741 gtgcagcact tattgtatct gcttctcctt tatatgcatt agttaatatc acttcatcaa
    10801 cttttttgat accatttacc tctttagcaa cactataact agtctttatt ctgtcatctc
    10861 cacccaatct agttacctgt gcccctgtgt tttttagttc agtttctact gacttactta
    10921 ttgataattc tttacctatt atgtatatct ttttaacatt ttttaatctt tgttttgttt
    10981 catttggtat cttatttttt tgtgcaagca aaattggagc atcaacagca cctgcaagac
    11041 cacttgctga aagaccatct gctatagaat tatccatatt taccataatt gctgtatcat
    11101 aactcttttt atctgctatt aatccagccg tctcatatat attgttacct ttaattgtat
    11161 ctgatgttaa tgcatctaca ttaggtacat ttattagaaa tatagctaat gttaaaccta
    11221 atgctaaaac tcttctaatt gttctcatat tcttccccct tgatatatca agtttaattc
    11281 aaaaatgact ataacatagt attacatcta cgctatagtc atttattata atttaataat
    11341 tatatatttg ttattatatc ataaattaca aaaagtttcc ataatattgt atagattaaa
    11401 ggaaaaattt acattttagt tacaatttac tagatttttg ttctaatgta cctatattta
    11461 gtaacaattt gtaataaaaa tcgatatcta tattacatat ttaattcact gttttacaaa
    11521 atgaaatttt attgtataca ataaatagat tatatgttta cataatctat attattttta
    11581 agtaaatctt ttatcgatat tattaagaat atatattaca tcaagtttat tacgtgcaaa
    11641 ccactatcaa cttaaatacc taaggtaaca cttgaagtag tagattcttg gtaacaataa
    11701 ttattgctat cattatcttt ttttaattaa gtatttacta tttatatatc aatctacttt
    11761 tcacttttaa tttaattcta atattttttt atatgtttta tgatatataa tgtgatatat
    11821 tctaattaat gatattttca agtaaaaaaa tgttactcta ttataaggtg atagtatact
    11881 tgaaaataaa taaaacactt aactttattt aaggagattt atgatgagta acaaacaagg
    11941 ttctaacatc aaagatgtaa aaattaaaaa taagttaata atattgaaat tactttctac
    12001 aaatacacct atgtccagag ttgatttagc taagtctaca ggacttacta aaatgacttt
    12061 atcaaatcta gttactgaac ttattaatga aaatatgatt agggaaatag agtcatcaac
    12121 tttaaatgca cattcatcag gtcgtaaacc tattttatta gatatttcta atatatcgcc
    12181 ttgtatttgt ggaatcctaa taagaagaaa tatatgtaag gtaattattt cagatttaaa
    12241 aggtaatatt gtaaaacaac tttctgaaac ttaccctaaa tttctatcaa atgatgtttt
    12301 aaaagatata ataaaaagaa tgtttactaa aataatgaaa atcaacaaga gagatataat
    12361 tggaattggt atttcttcaa taggtccagt agatgatata aatggtacca tactaaatcc
    12421 cccagatttt ggaaatgtat caaacctaaa tatagtagat tttataaaag aaatgtctga
    12481 tttgccaata tttttgataa atgatgctaa ttcgggtgca ttagcagaaa aaatgtatgg
    12541 tttaggtaaa aatatatcaa attatatata cctacacata atgaatggta ttggagctgg
    12601 tctagttcta gaaaataaac ttcatactgg caacctagga caaagtggag aaataggaca
    12661 tacatcaatt aattttagtg gaccattgtg cagttgtggt aacaatggat gtttagatta
    12721 ttatacaagt gtcagtaatc taattaaaag aattgaatca ttgagccata tttatcctaa
    12781 ctccccatta attaactgta aagatttttc tttagtcaag ttaatagatg aggcaaataa
    12841 taaagatagt cttgccatgt ttttgcttga tgaattttgt acatacgtat catatgcatt
    12901 agttaataca cttacattga ttgattgtag ttctataata ataggctatg actttaatat
    12961 acctggtaca tttatagaaa atacattatt aaaaaaattg actgcttcag caagtttttc
    13021 taaatataaa aaaataagtg taaggcattc aaattttgga gcaaatgcac cattaattgg
    13081 ctctatagcc attgtaagtt ataatttttt taatggtagt ataaattttt attaaatatg
    13141 taaaatattt aaacactttt attgaatatt tttccattta atattattat attttataag
    13201 agcatttaaa atttggaggt ataaaaatga tttcagctaa aatggaaaaa ttacttaatg
    13261 agcagattaa ccatgaatta tattctgcgt atctttatct ttctatgtct tcttaccttg
    13321 aagcagaagg acttaaagga ttttctaatt ggttttatgt tcaatataaa gaagagacag
    13381 accacgctat gtttttttac aaatacttac ataatgtagg aggaaaggtt cagcttgatg
    13441 ctatcccaat gccagattca gactttactt ctgcaatgga tattcttgag cgtacgttag
    13501 ctcatgaaaa aaaggttaca gctttaataa acaacttagc agctgtagca aactctgaat
    13561 cagactttag aacttctcaa ttcttacttt ggtttatatc tgaacaagca gaagaagaaa
    13621 caaattgtga agacaatata aaacgtgtta aacttgctgg agagggtggg ctattctttg
    13681 ttgaccaaga atttgctaat cgtacatatg cagctccaac aaacccacct gtgacaatat
    13741 aacgtttaaa aatttttaat ataataaaga aggtgtttta atgaaaatca agattgattc
    13801 ttatcattaa aacacctttt attattcgtt ttatacgtag tattttattg tttatacagt
    13861 gctatttcac aatgaaactt aaaactatac tttcatttta aaatattttt aaattaaatt
    13921 tggggtgact gaaaatcaca ctatctaact tacaaaatgt gattttcagt tggtgcttta
    13981 attatggttg aataccaaaa cttataaact atttatattt aactattaag gcatctactg
    14041 cacatacgcc ttttccttta ggatatacaa acactggatt taagtctatt tccttgactt
    14101 catccttatt ttcataagca tattttccta acttgaccat catatctgca agagcatcaa
    14161 tatcacatgg ctcacttcct ctatagccat ttaaaagctt aaatgatttt agttttttaa
    14221 gcatcataat agcttcatca tgatttatag gtaatggata taatgtagta tctttaaata
    14281 cctctacaaa tactcctcct aaaccgacta ataacattgg tccaaattgg tcatcattag
    14341 ttataccaat aataatttct ataccacttt ctaccatttc ttgaactaat ataccatcaa
    14401 tattagcatc tggttttgct ttttttacat tagttaaaat ctcattatat gcatctactg
    14461 cctcatctct attcttaatt cctattttaa ctcctccaac atcagatttg tgcaatattt
    14521 cagaagaatt tatttttaaa acaacaggat acttaatata ttttaagatt tcatctaatt
    14581 catcaatact ttttgcatta ccttgtcctg gaactggtac tccatatttt ttcatctcaa
    14641 tcttactatc taattctgat aatgctacta cattatttga ctctcttttc ttaacagctt
    14701 taaattctaa agttcttttt gaataatcat aatctataaa cttagccatt ttattaaaac
    14761 aagtaaatgt agttccaact gatgacatta taggcacttg attatcttct aatctagtcc
    14821 tataatctaa atatctattt ccttcaagtg taggaactgc aaacacaggt tttttcaatc
    14881 cttgttctct agcttcactt acagctttac aaagggtttc atgcatttca ttttcttcat
    14941 ctcttatatt tgcacctacc atagtaaatc caacactatc atccttttca aaggtatgta
    15001 ataaacctac tatcatatcc ttttcatgga ataatgctgt tgtagcatct agtggatttt
    15061 taggtgttgc aaatcctgga agatattttt ccatttcttc tttagtttca gaagatattt
    15121 ctgcaagttc tacaccattt tcttctgcta aatctgcaca aatagtattt tctcctcctg
    15181 agaagtttat tgctgcaaaa ttagaatttg caggtaaatt accatctaaa acactaaaag
    15241 cttgtgctaa acacataaac tgttctaaat tttccacaga aattactcca tatttttcaa
    15301 aaatactttc aaaagcttta ctcgaaccag ctaaatttcc tgtatgagaa gcagcagaaa
    15361 tagcaccttt ttctgacctt cctgatttca atattattac tggctttctt ttttgtgctg
    15421 ccctttttaa agcatctata aatttttgag gattttttaa accttcaagg taaattgcta
    15481 ttactgatgc ataatcatca tctacaagga aatctactgc atcttctagt gtaactatat
    15541 ttccatttcc tgttgaaaaa ccataagata tattaaaata atcacttgaa acaatttcag
    15601 cagttataaa tccactttga cctacaattc ctataccagg ttttttagta tctaaatccc
    15661 atttagaacc tcctgcccat agattaacct tatctataca atttagcaac cccatgcagt
    15721 ttggacccaa tattttcata tcgtatgtat ttgatatttc tataagttga ttttctaaat
    15781 ctgtaccttc ctctgtacct tcctctgcaa atccactagc atataccact gctgcctttg
    15841 ttcctaactc tccagaatct tttaatacag atggaactac atttctaggc gtacatacta
    15901 ctacacagtc tactacttct ggaacttctt gtatcgtctt ataacatttt ctcccaaaca
    15961 attcttctct tttgggatta acataatata ctctatctgt ttccttactt tttactatac
    16021 taagtgctgc acttcttcca aaaccaagtt tatcagtcac tcctactata gcaatacttt
    16081 ttggtctaat aagtttttcc aaactcataa attcacgctc ctatatgttt atagttgtga
    16141 ttttaagtga attttatctc aagatgaagt ttctcttggc actaaagatt attaaatctt
    16201 gagataaatc acttaagata agggtaattt atcaaatggc gttattatag ccttccatga
    16261 atgctgcttc attttgaaca ttaaactttc cttttccttt ttcctcaaag aaatcacaca
    16321 tagtttttaa agctaattct ttttcaaata acccagtttt agcaattaat gctccaagta
    16381 ctactatatt tgctgctttt ggattgttta ctttttgagc taattcctga caatttattt
    16441 taactacact tatatcttct cttaatgtta cattctcatc tattgcagat gtattaataa
    16501 ctactgttcc accttcttta actaaattta tataatctaa agatggttta ttcattgcta
    16561 ctaaaacatc tatttcttcc atatcaggcc cacctatact ctcatcagaa aactttacta
    16621 cactataggc ttttccacct ctcatagttg gaccatatgc aggcatccaa gttacttgtt
    16681 tccccaattc aagtgctgac tcagctacaa tcagaccaag agttaaaact ccttgaccac
    16741 caaaccctgc aaatactagc tctttttcca taactattca ccatcccttt gcttaaattc
    16801 gccaagagca taatatggca ctatttcttc ttccatccat ttgatagatt tctctagtga
    16861 tacaccccag ttagttgggc aaggtgctaa tatttcaact aaggaatatc cctctccatt
    16921 taattgagct tctattgcat tttttatata tttttttaga ttaattattt cctttgggct
    16981 atgaactgaa cctcttgcta catatgctac atcaaagaag tttgccacca tctcaggaac
    17041 tttcagtgga ctaccagtag tctttatatc tcttccattt acacttgttg ttgtgacttg
    17101 acccggcata gtggtccatg acatttgtcc accagtcatt gcaaaattat tattgtttat
    17161 tacaaataca gtcacattat gatttctata tgctgtattt aaagtttcag aaagacctat
    17221 aacataagca tctccatcac cttggtaagt cattactaat gtatctggaa gtgctacttt
    17281 aactcctata gctgtagatg aagctctacc atgtgcagtt tgcatcttat caccattcca
    17341 gctaaaattc atattgcaga cacaaccaac tcctaatgtt aatacatgat ttttttcata
    17401 tccatgttct tctattacct ctgctattat acgatttact attccatgac cacaacctgg
    17461 gcaaaacttg tttggtattg aaacaacgct aggtgttaat ttttctgtag ccatattaga
    17521 acacctcctt gatttcgcca gattttattt tgctataagt gtccattact tgcaatgttt
    17581 ttggtatatg atttccacta aataaaccat acacaggtac attttcttta catactttct
    17641 ttgaggctaa agcaacatct tctactaatt gacctgtgtc tgttgattct actgagataa
    17701 atccttttac atctttactt accttttcaa atgctttata tgggaaaggc catactgtta
    17761 ttggtcttat tattccaact ttttcacctt gttctctaag tcttctaaca gcattcatag
    17821 ttgttcttga tggtatacca aacgctacaa acacatattc tgcatcttct acttgataat
    17881 cttcccattg ttgttcattt tcagttattc tcatacgttt ctccatacaa aaagttggct
    17941 tttggttatc tgcaaccttt gcatggtctc tattacttcc atcataagtc caacctaaat
    18001 ctccttctct cttcttaaac tctggaaatt ctactggttc catcatttga cctaaagctg
    18061 cttctgtcaa aatttcgaca ggcactctgt acttctccgc tacatcaaat gagttataca
    18121 tcaaatctac agtctcttga atactgtttg gtgcataaac tatcaaatga taatctccat
    18181 ttcctccccc tctagtatct cttagatagt ctgtctgtgc tgagtccaat gagccaagac
    18241 caggccccca tctctgtaca tttacgatta cacaagggta atgatttgca cataagtaag
    18301 aaatcccttc ttgttttaaa gatattcctg gtcctgaaga actcgtcata gacctcattc
    18361 cacttgcata tgctccatat accatatata tagcagccat ctcattttcg gactgtataa
    18421 aagttcttcc aagttcagac attctatgtg ataaaaattc cattacctct gtttgtggtg
    18481 taattggata tcctgcataa aattcacaac ctcctcttag ggctgcttct gcaatggcgt
    18541 ggttcccctt ccacatcttt ttcatattat cccaactcct tctaagcctc ttgacatgct
    18601 tcttctttaa ttatttcaaa aacattatct ggacacacct gatagcaaat tccacaaagt
    18661 atgcatttac tctcatcaac ttctacatga gcataacctt ctttatttat cttacttgat
    18721 atttttaatg ctcctttttt acaagatata acgcagtatt cacaactttt acatctctct
    18781 gcgtttattt ttaagttcat atctacaccc cgtttcataa tatttctatc tattatccaa
    18841 tacttggctc tcctttaata tttaatattt cctttaaaac tgctacaaat ttcctatttt
    18901 cttccatagt tccaatactt acacgtgcat gtgtagcact tggtcttatt acaaaccctc
    18961 tttttttcaa gtcttcaaat aacttaggta tatctgtttt catatctaca taaaggaaat
    19021 ttgattgtga atctacaaca tcaaatccca tttttgtaaa ctcttcttta aagtaagcca
    19081 ttccaactct atttaattca tatgtttctt ttataaactc ttcatcatca agtgctgctg
    19141 ttgctccact tatagcaaca cgatttgcag agaaaggctc ttttactgta aataaagttc
    19201 ttattatctc atctttagca ataccatatc ctactctaag ccctgcaaga ccatatattt
    19261 tagagaaagt tcttgttact ataacgttat aattttccct tacatactta agtccatcca
    19321 cataattagg aactgttaaa aattctatat atgcttcatc caatatagtt ataatatttt
    19381 cagggacttt ctttaaaaat tcttctaact ctttatcatc cacaattgtt cctgttggat
    19441 tattagggtt acatacacat attaattttg ttttatctgt aatcttatct aatatacctt
    19501 gtaaatcata cttataatct tctgttaaag gtacttctac tggtatccct tcatttttta
    19561 tagttgcagt tctatatgat ggaaatgttg ggttacaata tataacttca tctcctctat
    19621 ttataaaagc ctcacctatt agagtgataa cgttatctgc accattagca acaataaaat
    19681 tttctggttt taaatctagc ttttcagcta attttcttct aagttcgtta gcttctggct
    19741 ctggataaag ttgaccttgt tttaacattt caatcatagc ttctattgct tttggtgatg
    19801 gtcctagagg attttcattt gaagctaatt ttattatttc ttttacacca tatttttcct
    19861 taactttttc tattggttca cctggaacat attgatgtaa ttcttttacg gtatttctca
    19921 ataatttttc tatcattttt aaaagccccc tctgtatatg tattttcatt tatataaacg
    19981 ctattgcgtc tacttacttt aatagcttaa attaaccatc tactcaactt tcttttaact
    20041 aagcatttct ttgatttaac tcttctctta tttggtttaa tttcttgtca cttactggat
    20101 atagtattgc tataacaaca gctattatta aaggtattgc catagaataa gaaatcatat
    20161 ttataaaacc tgatttaact gcttctgtga ctaccatatc agcttgatat cccattgagt
    20221 tcattaaaac tgttcttata gtagttgcaa gtaatactcc tacttgtatt gcaactggat
    20281 atagtgacat acttaagcca ggtaagtctt ttcctgattt ccaatgccca taatcacaag
    20341 aaccggcaaa gaaattaaga tttattattg atactacatt tgaaaaacct ccaccaattg
    20401 ccaacaacat agttactcct aaagtagttt tcccccaagg agtccatgca accaataagt
    20461 ggcatagtgc acatatagaa aaagaaatta ttgaagctag tttttgctct ctacagattt
    20521 ttataaacac tggtgcgaaa aacatgaatg ctacacttac caaaggcatg attgataaaa
    20581 atactgctaa tccacgttca tcttctatta catatttaaa ataatatgga gccaaaggtc
    20641 ctaatcctat agatcttata catataagaa attctaaaca aaatgccatc ataagtggta
    20701 cattagtgaa taaagctttt gccatttcac ttgctttaat ctttggcttc tcttcttttt
    20761 gaagaacttc ttcttctgct ccagatttta ttatctctgt tgaagaaaac caaaatacta
    20821 aaaggcatcc tgctgcaaag aataagtagg tacctaaata acccattcct tctccaccta
    20881 atacatctgc aaataaaact aataataacg gatatgaaaa acctactaag aatttaccaa
    20941 cttctttaaa tatattcgta gtagttgagc ctataactcg gtctctaggt gtcttagcaa
    21001 ctacagggta aatagcataa attatagtga aaactacttg ctgagcacaa gatgctatta
    21061 ataataaagc tgtcatcaaa ggtaaaagta atgctggact tattttcatt aatggaacta
    21121 tgaaaaatat tccatatgtt aatgctaacg ctgctggtgc atatctaagc catggataat
    21181 actttccttt tttgaatggt tgtttgtcaa atactgtacc tgttatagga gctacagcaa
    21241 tttttatgaa agattgtata atttgcatac cacctgccat aattacacca agttttgcca
    21301 catcagttaa aaaaatattt gtaacagttg atacaaagta acctataaaa ttgtacgcta
    21361 aatttataga acttgaatat gtgtatattg ctcttttctt agggtctctc atatcatctc
    21421 taaaatttga tataagattt ccttttggtt tgctttcttg actactcaca tctacccctc
    21481 ccttataaaa tttacttact ttttattatt cacgtataat aatatatatt ttgaatctta
    21541 aatatctcat tcttgattca ggagtatatt tttatatgtg tataatttta atttaattat
    21601 attctcaaaa ttcataattg tcaaacactt tttaagtttt attttttact actaaaatta
    21661 actaaaaagc tatttagact taatttaggt ttgtttttta ttattttctt gttttgaaat
    21721 gtcattgaaa tgcgtatttt aaattatttt atcatatttc tagtgatttt aattttttat
    21781 aattttattc aagaataatt tattcaagat atttctatac tacatccaga tattaaaaat
    21841 atctttttct tatttaaatt ccttttattt ttatacatgt actattgatt taaaaataaa
    21901 agcgtgttac aattacaaaa aagaatctat gagataaata tcaatatgca aaaatttcag
    21961 aattttcaat tttctatttt tacgtaattt ccatctaata tcataaatta ttatagctat
    22021 attaatctaa aaccaataaa acaaatatcg tactactttt atataaaata tattttaaat
    22081 atattttgta tattttatta aaatatttta taaaggagaa aagactatgt tacttttaat
    22141 tgttacgtgt gcaatataca tatggattgg tttttatttt tcaaaaaaag ttaaaacagc
    22201 atccgatttc ctaatcgcag gtagaaatct gcctttgcct atactagctg caaccattgc
    22261 tgctacatct tttggaggag ggtgcttagt tggtggagtt caatggggag ctgaaagagg
    22321 actttgggtt ggaatgtatt ctactatagg tgcagcttta gcttgcttta taaatgcatt
    22381 tttcgcagga aaattaagaa gcttatcttg tgatataaca cctgctgatt atattgaaac
    22441 tagatatggt catagtgtat ttttaagagc ttatcaaagt cttgtaacac caatatctat
    22501 actagctatt atgggtagtc aattgatttc ttttggttct gtatctactg catttggtat
    22561 tccttatgat atagctgtaa ttataggagt tatagttatc attatatata cttatacatc
    22621 aggaatgtgg ggagttgcag tatcagcatt tattcaactt gctatttgta tagtgttttt
    22681 gccaatagta gcttatataa gcttaaaatt agttggcgac aaccctttac ttatgttaca
    22741 atcaatggta aaagaaccat tctttccagg aaataaatcg attagtgatt ttatgtatac
    22801 agttttacca ttagttttag gctcaatatt ttcttatgaa agttttttaa gatatcaatg
    22861 tgctgataat gctaaaaatg cagttaaaag tagtgtaatt gcaggattta tactattatt
    22921 tcttgctttc cctataggaa taattggagc tattggtggt agtttatttc caaatatatc
    22981 atctgttcag gttttacctc aaatgatatc gactactttg ccacctttaa tatctgtatt
    23041 attcttagct gctatattgg ctgccataat gtctactgcc gattcattaa tgacctcaat
    23101 gagtgctatt atatcaagag atatttataa caaattatta catcctaata tagaatttaa
    23161 tgatttaaaa aatactctaa agtattctca aattgcatca gctttgacag ctataatagg
    23221 tgcaatcata gcacttaaat ttgatagttt attagaatta ttgttttggc cagctccatt
    23281 atgtacaggt gtaatatttg caccatttgt aattggtctt tgctggaaag gtgctacaaa
    23341 aaaaggagct atctatgctg ttatagtaag tgttatattg gcattattaa atatgattgg
    23401 tattcttact gtatttgaca gaattttggt tcctataata ggtggttcta ttacaatatt
    23461 tatagttagc aaattttcaa aaaaagattg aaaagagagg tatacacagt aaatatgtca
    23521 aaatcagaaa agggcaaaga aacaaaagct agtattataa gtgctgctag agaattattt
    23581 tttgagcaag gttatcataa gacaacaact aggcaaattg cagaaagagc taatataaat
    23641 ttaggtctaa taagctatta cttctcaagt aaaagcgaaa taggagctat aatatatgaa
    23701 gatataagaa atgaaatgca gtctttaatc tataactacc atgaagaagg tactatgatg
    23761 atgttctttc ttgctatgaa tgctgacctt tgtttccttc taaaaaacga agcatataga
    23821 aatttttatt tggatatagc ttatgaagaa gctattttaa gctatcaaag aagtgtaacc
    23881 gaaatggtca tgaaaagata tgttaatgat aaagaatcta tagaacatga tgaattaata
    23941 ctttcttgta ttggtatact tgctatgaaa cctgaaataa ttagagttta tacttcacac
    24001 aagtacgata tatcttctca agctgtaata aagcatttta caaaacagtt tcttattaat
    24061 cttggtcata gtacggattt atgcgaagag attttagagg aattgagtaa atactatata
    24121 gatatagttg acaattttac tccaataata actcgtgtaa gaacttaata aaattttatt
    24181 aaattcttag agactgaaat tttaaaatca taatttgatt ttaggatttc agtctttatc
    24241 atatttaaag atattttata gtatacctgt taataccata agtgtactat ccaattatat
    24301 ctataaattt ctttatccat aaattccaaa gacgccattc atgcccccct acacactctt
    24361 catattcaac atctacaccc agagaatctg catatttttt aaacatctga ttatttttat
    24421 ataaaaaatc tctatcacca caaaattgat aaattttagg aatatcttca tttctttctt
    24481 taaggttctt aagtatgtaa agtaaatcat tctcactatt tctagcgtct tctggtctac
    24541 caaaatcgtg aaatagaatg tctgcattgg tttctatttg ttgattttct aactcatgaa
    24601 tcatatcagg cgaaccagaa aaacttgcaa ctgccgaaaa ctcttttggt tttgaaagcg
    24661 ctaattttaa agctccatat ccccccatag acataccagc tacaaagtta tcttcccttt
    24721 tatctgataa aggaaatata gctctaacaa atttaggtaa ttcctcgctt acaaaagtaa
    24781 aatattggtg tccatacgcc atatcagtat aaaaactagt ttctactctt ggtattacta
    24841 gggctatatt tttattttta gcataatgct ctacattagt atatctaatc catgagcttt
    24901 ggtcatcttc taaaccatga aataagtata atgttttaaa tttaccttca aaatcatata
    24961 tctctttacc actaaaaagt tcttttccat ttgctacagg caaaattaca attatatcag
    25021 tttctcctcc agtatattta gatttaaatt tacattctat aaatgccaca aaaaacacct
    25081 cttctataat aattttatat ctaaaaagca ccaagagttt aactttctca gtgctttaaa
    25141 tattgcttaa tttatatatt tttaattata cataatattt tttagctaca tataatcgga
    25201 agtatctgtc ggtaatccct ttttgtccaa tttactttca acaatatcct taattataga
    25261 ataaattact gcaaacattg gaactcctat aaccattcca ataaaaccta ataattttcc
    25321 tgcaaccaat aaggagaaca aaatccaaaa tgcagatata ccaattgaat ctccaagtat
    25381 tttaggtcct ataatatttc catctatctg ttgtattatt aatataatca acaataacca
    25441 gaaagctttt ataggagata caaacatcac tattagcgta gatggtatag ctccaaataa
    25501 aggtccaaag aaagggataa tatttgtaat accaattata actgatatta ataatgtata
    25561 tggcatttta actaacgtaa gtattacaaa tgttagaata cctataatga atgaatctaa
    25621 tattttgcca cctaaaaatc ttccaaatgt atagttactt ctatgagtta attctaaaat
    25681 tctggcagct tgtttttctg taaatactgc ataagttatt tttttgctta atccatagaa
    25741 tttttcttta tcaattaata agtacactga aacaattaat cctagtacaa tattccatat
    25801 actagaggct acattcttta acatacttcc taatattggg attaaatctg ttacaaactt
    25861 tataatatat gtaacaaatt cattccactt atcaactgcc aaattaaagt attgctcatc
    25921 aagatttaaa tcagtcatta atttatcaat aagcttagtt gcattgttta catacatagg
    25981 tatatcattt gctagtccaa caatactctc aattacttgt ggcaatacga aatgcataaa
    26041 taagtaaagt atcaatgtag ctgttgcata tgttaataaa agacccaagc ctctttttga
    26101 actttgtttt agttttttta atttctcact ttttataaaa attctgtctt cataaaactt
    26161 taaaataaaa ttaagaagat atgcaatagc aaatcctatt ataaaaggtt gtaatgttgt
    26221 aaatatagca tctaaattat tagaaaatac atcaatttgt gatgatacta gataaaatat
    26281 aatactacta gcagctatta taaatgtata aattgctatt gttgtgtatt ttgtattcca
    26341 attaattttc attttttcct ccttatttct atataattaa attttatcac aaaatcacca
    26401 cttttataac aaatatacca aattaaaaat aaaatatatt cagaatacaa atactcaatt
    26461 ttatttatat ttattattct acaatataac ctacattatc tttttaagaa ccttaattaa
    26521 tttattatcg tatggagcat atctaatagg gacatccaaa tttaattttt ttaacacact
    26581 cttatagtga gtaaatgtat cgaatccagc ttttccatga tatgagccca taccactttc
    26641 accaatacca ccaaaaggta agtaattcgt agctatatga gtaactgtat cattgataca
    26701 acatccgcct gctggaatca tttctaaaag tttattttct aggtacttat tttttgtaaa
    26761 aatataaagt gccaatggat ttggcatttg tataattttt tgtattactt catctaaatc
    26821 tttatatgtt aaaatgggaa atataggccc aaatatttct tccttcatta tattatcatc
    26881 ccaattaaca ttgtctacta tagttggctc tatctttaat gtctccttat tataatttcc
    26941 accatagact atcttatctt tatcaataag agataatatc cgattaaaat gtctctgatt
    27001 tatgatttta ggaaattgct cattattaca tgcattatcc ccaaaatact tattagtata
    27061 atattttatt ttctctatta actcattttt tctatcttca tgcactaaaa cataatctgg
    27121 agccacgcag gtttgtcctg catttattag ttttccccaa gtaagtcttt tggcagtaag
    27181 gtctatatta gcatctttta aaatgataca aggacttttt cctccaagtt ctaaagtaat
    27241 aggagttaaa tgctctgatg ctgatttcat gattatttta ccaacattag tacttcctgt
    27301 aaaaaatata taatcaaatc tttccaatag taacttttca ctttcttctt gacttccttg
    27361 aacaactgca acatattctt ttgaaaaagt atcttcaact atgtctttaa ctacactaga
    27421 tgttgacaca gaatattcag aaggttttaa tataacacaa ttccctgctg ctaatgacca
    27481 aactaatggt ataagtgcta attgaaatgg ataattccaa ggtgacatta tgagagtaac
    27541 accataaggt tgtggaacaa ctttggatat agatggaaaa ttaaccatac ttgatttaac
    27601 tctttttatt ttgctccatt ttcttatatt ctttatagca aagtttaatt cactataaaa
    27661 catgcctacc tctgtcataa aaccttcaaa atccgattta tttaaatctt tctttagtgc
    27721 taaaagtatt ttttcttcat tttgtgatac aactaactta agtttcttca actgttctat
    27781 acgaaacgat atatctcttg ttttacctgt attataatat tttctttgca ttttaactaa
    27841 ctcttttata tccattgtta aaaatccttt ctttaagaat tatactaata catttttaga
    27901 aaaagattta aatttatcct aacattattt tttatatcat aataaattca tctcaatata
    27961 acataaatct tccaataaaa aaagcccctt attaagtata agtaagctta taaaatagtt
    28021 tattttaaaa taaacatttt ttaaaattat aaccttattg aaacaattaa attatccatc
    28081 tttaataata ttattttata aataatgtct agtaagtttc tatgaaatct aactttagat
    28141 aataaataat tacaaatata tacctcttaa agttctctta tataatcaag tattggagtt
    28201 aaattttctt tattacacca atcaaaggct tctccagaca ataaaggtgc ttctgctggt
    28261 ttaagacctt gacgttcttt tttagctata gattttttaa aaaaactaca aagagtataa
    28321 tctataaaag acatttttgt ctcatcccat gccccacgac aataaaagca aggaattttg
    28381 tttaattcat ccttaaaatt tacttctctt aatttcttta ttacttcatc atcatatgga
    28441 gcagctccta caccaaatac tactaaattt tttttctgca attctttata attttttttt
    28501 aagaaagaaa ttcccgctat attacaagca taaagacctc ctcctaaaat aatcgtatca
    28561 tacttcataa ccttttctat attaatattc ttagtttcaa aaatatcaca agacaataat
    28621 tctgaaagcc atttagcata tttttttgtt gaaccatact tactcttata aatcactact
    28681 acacttttca tataaattct cccctctctg atgtcataca aagttgattt gatacttgct
    28741 tattctccaa cgtcattatt ttctacataa tttttcacat tttcaattcc tatacttaat
    28801 ttcataattc caaaaaataa ctgttccgct tctttctctg taaaatcttc aaataaaagc
    28861 tgtaatactt tttcctgcat acctctcact tttttagaat actcttccac tctatctttt
    28921 gtcacaagac agatagctct tgaatctttt tcattttgct caatttctat aaaacctttc
    28981 ttttctaaag caatagctag tttttttaca ttttgtcttg aacaccccat taattctcca
    29041 agtttggtta atgtaagagt ttcatctaca gagtccgcaa tagctaaaag taaccattgt
    29101 ttcattgtta attctgggtc taatttatca catgtagttt gaagtttatt ttgcattaca
    29161 aatatacttg caaatatagc ttgttttcta ctatcatcat ctaccatata ttttttcatt
    29221 aaactttctg catccattat tatacacttc tctttatctt agattttaat tttttgataa
    29281 ttttaaatag taactaatta ctttatatta tagtaattag ttactattat gtcaataaat
    29341 ttatttttat tataaacggc aaaacggcat agcattatgg ctataccgtt tcataaaatc
    29401 atatttacaa tcaatttata ataaattata aatta
//
LOCUS       DAFAZV010000051        29204 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFAZV010000051 DAFAZV010000000
VERSION     DAFAZV010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29204)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29204)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29204
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.051"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(121..894)
                     /locus_tag="KOU88_003147"
     CDS             complement(121..894)
                     /locus_tag="KOU88_003147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SigB/SigF/SigG family RNA polymerase sigma
                     factor"
                     /protein_id="HBK3213003.1"
                     /translation="MKNVANATHYLNMDTKELFNLYNKNKNVDIRNILIERHLYLARL
                     LAKKYINKGVDFEDIYQVASLALIYAIDRYDVEKGFEFSSFATPTIVGEIKKYFRDKV
                     WTLRVPRRIQELSKKISDAKIKLEQENKKHPKVKDIADYIGVSEEDVLEAMEASYGYQ
                     PMSLDSSSNDDSEDKDITLIDKIGKEEGNFGSIEYEDFINKFIETLNELEVKIFKDRF
                     FFDKTQSSIAKELGISQMTVSRLEKKVVEKLKKEYEKNL"
     gene            complement(894..1280)
                     /locus_tag="KOU88_003148"
     CDS             complement(894..1280)
                     /locus_tag="KOU88_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3213004.1"
                     /translation="MEITTNPDYVSIIRLTASGIANKMGFPIDDIEDIKVAVSEACTN
                     AIKHSKDDVFNIVFNILDNAINIEIQDNGKGYDVSSISTPDLENPKESGLGLFIIKTL
                     MDDVDIESEHNQGTKIKMTKYLGVDI"
     gene            complement(1305..1622)
                     /locus_tag="KOU88_003149"
     CDS             complement(1305..1622)
                     /locus_tag="KOU88_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STAS domain-containing protein"
                     /protein_id="HBK3213005.1"
                     /translation="MSMNIDSNLDSQNKFWNVCLDGELDVSTADKLKEHLHALIEKNM
                     LDVKINLKDLDYIDSTGLGAMIGVLKKLKINEKEIYIVNPKSNVRKIFTITGLDKIFK
                     VEG"
     gene            complement(1634..1894)
                     /locus_tag="KOU88_003150"
     CDS             complement(1634..1894)
                     /locus_tag="KOU88_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBK3213006.1"
                     /translation="MNAWGWQIGAVLVGSSALIVAIYLAKTLNSINKVVEKAYKIVDY
                     NERHIQDIVENASSISKGIDDIVYVINKILSIGNIFKIIKRK"
     gene            complement(1894..2190)
                     /locus_tag="KOU88_003151"
     CDS             complement(1894..2190)
                     /locus_tag="KOU88_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK3213007.1"
                     /translation="MCNKRSCKKGGFLLLGAILGFIFGMFFAPKKGSELRKETKEKFN
                     DVKENPKEVLHETFNDVKERIINLVDDDNNEEDIKISEEDIVISKSFDDEGDVN"
     gene            complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="KOU88_003152"
     CDS             complement(2259..4685)
                     /gene="gyrA"
                     /locus_tag="KOU88_003152"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBK3213008.1"
                     /translation="MEENNKILPIEIAEEMKKSYIDYSMSVIAGRALPDVRDGLKPVH
                     RRILYSMSELNLTPDKPYRKSARIVGDVLGKYHPHGDTAVYYAMVRMAQDFSTRALLV
                     DGHGNFGSVDGDSPAAMRYTEAKMSKLSLELLRDIEKETVDFKPNFDESLKEPSVLPA
                     RYPNLLVNGSNGIAVGMATSIPPHNLAEVIDATVYLIDNPECSVDDLIKFVQGPDFPT
                     AAIIMGKESIAEAYRTGRGKVKVRSRAFIEELPKGKQQIIVTEIPYQVNKAKLVERIA
                     ELVKEKRIEGISDLRDESNRNGMRIVIELKRDANANIVLNNLYKHSQMEDTFSIIMLA
                     LVDGQPRVLNLKQILYHYIKHQEDVVTRRTKFELNKAEARAHILEGLKIALDNIDAVI
                     SLIRASKTGQEAKLGLIEKFKLTEIQAQAILDMRLQRLTGLERDKIEAEYEDLIKKIN
                     RLKEILADERLLLNVIKDEITIIKENYSDERRTEIRHAEGEIDMRDLISDEEIAITLT
                     HFGYIKRLPSDTYKSQKRGGRGISALTTREEDFVRHLVTTTTHSRLLFFTNKGRVFKL
                     NAYEIPEGKRQAKGTAIVNLLQLSADEKIATLIPIDGNDENEYLLLATKKGIVKKTKR
                     EEFKNINKSGLIAIGLRDDDELIGVELTDGKQEVLLVTKEGMSIRFDENDIRYMGRTA
                     MGVKGITLSKEDFVVSMNLCSKGTDVLVVSKNGFGKRTNIEEYRSQIRAGKGIKTYNI
                     SEKTGTIVGADMVNEDDEIMIINSDGVLIRIRVNEISLFGRVTSGVKLMKTNDEVNVV
                     SIAKINIEEE"
     gene            complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="KOU88_003153"
     CDS             complement(4705..6606)
                     /gene="gyrB"
                     /locus_tag="KOU88_003153"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003226808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBK3213009.1"
                     /translation="MKQEYGASQIQVLEGLEAVRKRPGMYIGSTSPRGLHHLVYEVVD
                     NSIDEALQGYCSDIYVSINEDGSVLVKDNGRGIPVEIHPKTGKSTLETVLTNLHAGGK
                     FGGGGYKVSGGLHGVGVSVVNALSKWMVAEVYLNGKIYKQTYEKGLPTSKLEVVGESQ
                     DKGTMIQFMPDETIFDEIEFKYETLEYRLRELSFLNKGIKIVFEDKREGQEKRKEFHY
                     TGGLVEYIKYLNKSRTGIHDDIVYIDKKVDDCFVELAMQYTDGYTENIYSFANNINTH
                     EGGSHLSGFKAALTKTVNDYAKRNKFLKENDVNLLGEDIREGLTAVVSVKLPEPQFEG
                     QTKTKLGNSFMRGIVDSVTVDELGSFLEENPSTARIIVDKALRAQRAREAAKKARELT
                     RRKSVLESTSLPGKLADCAEKDPSKSEIFLVEGDSAGGSAKQGRDRNSQAILPLRGKI
                     LNVEKSRLDRILSSDEIKNMITAYGCGIGEDFDIDKARYHKIIIMTDADVDGAHIRTL
                     LLTFFFRYMRPLIDEGYVYAAQPPLYKVTKQKKEHYVYSDKELNILLDEIGRNGVELQ
                     RYKGLGEMNAEQLWETTMNPETRTLLQVTVEDAAIADEVFSMLMGDKVAPRKEFIEEN
                     ARFVRNLDI"
     gene            complement(6607..7722)
                     /gene="recF"
                     /locus_tag="KOU88_003154"
     CDS             complement(6607..7722)
                     /gene="recF"
                     /locus_tag="KOU88_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBK3213010.1"
                     /translation="MKLKSLQLVNFRNYKKLHLEFNGKVNLLVGKNGQGKTNIVESIY
                     MLSFGKSFRTNKDKEMVRFNSENLYIGGSFSKYNKYSLIELIIGKDKKGIRINKVPLQ
                     KIQELLGNLNVVIFSPEDLRLVKEGPKERRAFIDKEISQIIPKYYKYLTNYNKTLSQR
                     SRVLKNIHVDEALLDVYDDTLAKYGSYIYILRRDFIKKIANISENMHMNLTNGVERLS
                     IRYKNQINITDEDTIDTVYNKFLAKLSSNRPNDIESKTTRYGIHKDDLNIFINDLDAR
                     LFGSQGQQRTASISLKLSEIELIKNEVEEYPVLILDDVFSELDEARQKLLVNNLSNVQ
                     MFITSAEVSHKKIFDEKNVTIFNIENGDVISIENGGN"
     gene            complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="KOU88_003155"
     CDS             complement(7740..7946)
                     /gene="yaaA"
                     /locus_tag="KOU88_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBK3213011.1"
                     /translation="MTEITIESEYIKLDQFLKLAEIASTGGHAKFLIQEGLVTVNDEI
                     ELRRGKKIKSGDIVEIEGTKIKVL"
     gene            complement(8083..9189)
                     /locus_tag="KOU88_003156"
     CDS             complement(8083..9189)
                     /locus_tag="KOU88_003156"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBK3213012.1"
                     /translation="MKIICNQKILANRIGIAQKAINGKTTIELLKGILISTEEGQLKL
                     TGYDAEIGIETYVQAEIIEKGDVVVDARLFGDIIRKLPDSFVEIETDSENNIYINCVN
                     SRFKIKGYAAKEFPKLPELNEEDLYSIPQEILKNMIKQTVFAISQDQTKPVLMGELLE
                     IVDRNLNLVAIDGYRLAVKSCSVDSLTENIKVIIPGKTLIDVNSLLSGEDNVKVGFNE
                     KNAIFIINDTKIITRLLEGDFIDYKKLLPREHNSRVKLNTKELLNSIERASLLSQSEK
                     NNLIKLSIRDKVMAITSNTEKGNVYEEVEIDLDGDYLDIAFNSRYFIEGLKNIDNEEI
                     FIEFTTNVNPCIIKPTDDVNYIYLLLPVRISSNI"
     gene            complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="KOU88_003157"
     CDS             complement(9431..10753)
                     /gene="dnaA"
                     /locus_tag="KOU88_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBK3213013.1"
                     /translation="MMDIVSLWDKTLQLIKGDLTSVSFNTFFKNIVPLKIHLNDLILL
                     APSDFNKDILENRYLHLIEDAISQLSLKKYNIKFVLSEKEVADLNSDSTDLNYRVLYP
                     NLNPKYTFDTFVIGNSNRFAHAACVAVAESPAKAYNPLFLYGGVGLGKTHLMHAIGHH
                     IVSQKKDSKVVYVSSEKFTNELINSIKDDKNEEFRNKYRNVDVLLIDDIQFIAGKERT
                     QEEFFHTFNTLHEANKQIIISSDRPPKDIPTLEDRLRSRFEMGLITDIQAPDFETRIA
                     ILRKKAQLERIDVPNEVMSYIAKNIKSNIRELEGALTRVVAYSSLSNRVISFDLATEA
                     LKDIITTSKNEEINVLRIKEKVSSVFNLKMEDFNSKKRTRSIAYPRQIAMYLTRELTD
                     LSLPKIGEEFGGRDHTTVIHAHDKVSKDIEESEEIKTKIDKIISDLKG"
     gene            11409..11546
                     /gene="rpmH"
                     /locus_tag="KOU88_003158"
     CDS             11409..11546
                     /gene="rpmH"
                     /locus_tag="KOU88_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBK3213014.1"
                     /translation="MSKRTYQPKKRQRSKEHGFRKRMKTSNGRNVLKRRRAKGRNRLT
                     H"
     gene            11624..11968
                     /gene="rnpA"
                     /locus_tag="KOU88_003159"
     CDS             11624..11968
                     /gene="rnpA"
                     /locus_tag="KOU88_003159"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBK3213015.1"
                     /translation="MDFNRTKGLKKDSDFRKVYKHGKSFANKYLVIYILKNKSDYSRV
                     GISVSKKVGKAITRNRVRRLIKEAYRLNIDEKIKPGYDIVFIARVSSKDATFKDIDKS
                     IKNLVKRTDISI"
     gene            12000..12251
                     /gene="yidD"
                     /locus_tag="KOU88_003160"
     CDS             12000..12251
                     /gene="yidD"
                     /locus_tag="KOU88_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBK3213016.1"
                     /translation="MNKIIYILKEISKYLSNLCIYLVRFYQKYISPLKGPTCRFYPTC
                     SQYSIEAFKKYGFVKGMYLTIRRLLKCHPFHPGGYDPLK"
     gene            12283..12990
                     /locus_tag="KOU88_003161"
     CDS             12283..12990
                     /locus_tag="KOU88_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBK3213017.1"
                     /translation="MNIIGNFLGLILKVIFEFVNHYGISIILFTILVKIILLPLTIKQ
                     TKSTKAMQDIQPRIKEIQEKYKNKPEKQNEEIVKLYGEAKINPLSGCLPLLIQFPILI
                     GLFSVLREPVAHGVFANKAAFLAADNGFLWIKSLTSPDYVLAVFSGASAYVMQKVMTP
                     KDQLQGSMKVMTYVMAGMSFYWGFIFPAGLTLYWTVSNLFSIAQYYLIMNPLKAKLAA
                     NSKEEKVNEKKPKINKK"
     gene            12959..13588
                     /locus_tag="KOU88_003162"
     CDS             12959..13588
                     /locus_tag="KOU88_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HBK3213018.1"
                     /translation="MRKSLKLIKSKSKEEAISKVIAELNLKAEDIEVEILENPSKGFL
                     GFIGAKDGTYEIFVIEREVDVAKNFIEVMLKNANVDAKVNVSQKDNLIMVDIEGKEAA
                     SLIGRRGETLDSIQFLTGLALNKINKDSHTRVLVDIENYRSKREESLIRYANKVAREV
                     AKTRKTKKLDYMNPYERRIIHSALQNDKYVITYSEGTDPYRRLVIECKR"
     gene            13700..15079
                     /gene="mnmE"
                     /locus_tag="KOU88_003163"
     CDS             13700..15079
                     /gene="mnmE"
                     /locus_tag="KOU88_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBK3213019.1"
                     /translation="MFIDDTIAAIATAPGEGGIGILRISGEKALKVAEEIFKSMSGKS
                     IEEYNKRTLIYGNIVDNENIIDEVLLAYMKGPNSYTGEDVIEINCHGGFISVKKILEL
                     ILSKDVRLAEAGEFTKRAFLNGRIDLSQAEAVIDVIKAKTDIAHEVAQNQLEGSLSKK
                     IRELRDKVTEILAHVEVAIDYPEEDIEHITYQTLKEKTDELKKDIKKLYDTAESGKIL
                     REGLKTVIVGKPNVGKSSLLNSILGENRAIVTDIPGTTRDVIEEFVNIKGIPLKIVDT
                     AGIRDTDDIVEKIGVEKSKESFTSADLIVMVLDASRKLSEEDIEILEKLKDKQTIVLL
                     NKNDLKQEIEEEKILKYVENNSIIKISALQQEGIEELQDKIESMVYKGSIKNNSSLVV
                     TNSRHKDALSKAYKSATDALIALEQSMPFDFVEVDLKNIWDYLGYINGDTVTEDLLDN
                     IFHNFCIGK"
     gene            15174..17069
                     /gene="mnmG"
                     /locus_tag="KOU88_003164"
     CDS             15174..17069
                     /gene="mnmG"
                     /locus_tag="KOU88_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBK3213020.1"
                     /translation="MIKFEAGKYDVIVVGAGHAGCEAALATARMGYKTLIITMSLDSI
                     ALMPCNPSIGGTGKGQLVKEIDALGGQMGLNIDKTYIQSRMLNTAKGPAVHSLRAQAD
                     KFKYHEEMKKTLEDEPNLDIAMDEVVEILHEGNVVIGVGTKLGCSFKSKAVILATGVY
                     LNSKIYMGEVAFYEGPNALGYAKYLTNSLVELGLRMRRFKTGTPARVHRDSIDFSVMS
                     LQEGDEKVTPFSFMNENIEKKQEPCYLTRTTEETQKVILDNLKRSAMYSGVIESTGPR
                     YCPSIEDKVVRFSDKTSHQLFIEPEGLNTKEMYIQGISTSLPFEVQLDMYKTIKGLEN
                     CKIMRPAYAIEYDCVDPTQLKISLEIKGVENLFSAGQFNGTSGYEEAAAQGLMAGINA
                     VRKIEGKEPFVLDRSEAYIGVLLDDLVTKGTNEPYRMMTSRAEYRLYLRQDNADMRLT
                     QKGYDIGLVKKDRYERFLNKKAAVDKEFERLKNERVTPKEVNSLLEEKGATPIKVGIS
                     LYEFLKRPEVTYELLEELGKGAGDDVSREVKEQCVIITKYEGYIEKQLKQIDQFKKLE
                     NKKLDEKINYSSIEGLRLEARQKLDDIKPISIGQASRISGVSPADISVLLIYLEQIRR
                     TRGGKGE"
     gene            17062..17781
                     /gene="rsmG"
                     /locus_tag="KOU88_003165"
     CDS             17062..17781
                     /gene="rsmG"
                     /locus_tag="KOU88_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBK3213021.1"
                     /translation="MNNIELLKNGIEGFNIDTNDSMLEKFKIYREILVDWNKKMNLTG
                     IEDEKEVYIKHFLDSISAVKNGYIKNGMSIIDVGTGAGFPGIPLKICLDSLELTLLDS
                     LNKRINFLEEVSRVLELDNITFIHGRAEDFGKNEDYREKYDVATARAVAGLPILMEFC
                     VPFVKVGGYFICLKGPNANLELEESQKAIDVLGLEYIEKIDVELPEVDLNHNILVFKK
                     VMETPVKYPRKAGKPAKNPIK"
     gene            17944..18729
                     /gene="noc"
                     /locus_tag="KOU88_003166"
     CDS             17944..18729
                     /gene="noc"
                     /locus_tag="KOU88_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HBK3213022.1"
                     /translation="MEDKRVMEIPIEDVVPNPYQPRKIFSQVSLEELSNSIKVYGIIQ
                     PITVRAKDGKYELIAGERRLRAAKLAELKTIPAIINNMNDESSAVLALLENLQREDLN
                     FIEEAIGYENLIKEHAFTQQQLAEKLGKNQSTVANKLRILKLPNDIKMKLIENNLTER
                     HARAFLKLPSEDLMQSVLDKVIKNELTVKKTEKLIQDVLEETKVQEEPDKKQNIKGAM
                     SIRIYINTIKQAFDAISNTGIDAKYNEIDKGDYMEVVVKIPKK"
     gene            18864..19637
                     /locus_tag="KOU88_003167"
     CDS             18864..19637
                     /locus_tag="KOU88_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK3213023.1"
                     /translation="MGKVIAVFNQKGGVGKTTTNVNLSASLGTLGKKILVLDLDPQGN
                     TTSGYGINKNEVENTIYEIMLDGLHIKEAIISTEFENVDVVPSATELSGAEIELTSKT
                     NREYILKNSIKAVIDEYDYIFLDCPPSLGMLTINCLTAVDSVLIPIQCEYYALEGVSQ
                     LMETIKLVKSRLNADIEIQGVVLSMFDGRANLSIQVVEEVKKYFKGSVYTTLIPRNVR
                     LAEAPSHGKPVIYYDKRCRGSVAYLELAEEFIDLEEEEW"
     gene            19639..20502
                     /locus_tag="KOU88_003168"
     CDS             19639..20502
                     /locus_tag="KOU88_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBK3213024.1"
                     /translation="MENKSKRSNRLGRGLSALIPEIKGETSEKEIVNIDIDKIYPNEV
                     QPRKQFDEEKIKVLSDSIKNYGVLQPIVVKMDENNKYMIIAGERRFRASKLANKNQIP
                     AIIKDIDMKDIMEIALIENLQREDLNSIEEALAYKSLIEHYNVTQEEISEAVGKSRPH
                     ITNTLRLLNLGQDVIEMIDSGRITAGHGKALLRIADKDLQLQIAKKIEEEELSVREVE
                     NIAKKISENKQEEPKKSKPKDVFILDVEDKLRNIFGTKVNISKGKKKGKIEIEYYNDD
                     DLNSIVSMLLE"
     gene            20535..21677
                     /locus_tag="KOU88_003169"
     CDS             20535..21677
                     /locus_tag="KOU88_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBK3213025.1"
                     /translation="MIYLDNAATTYPKPERVYNAVLDCMKNYCANPGRAGHKLAMRAA
                     REIYDTRENIAKLFNVSNPMNIVFTSNATDSLNLAIKGVLQEGDHVITTSMEHNSVIR
                     PIKALEKRGIENTVVKCDYEGFLDYEDLEKSIKNNTKLIVTTHASNVCGTLIDIKKVG
                     EIAKKHNILFLVDASQTAGVYDIDVNECNIDMLAMPGHKCLFGPQGTGILYVREGLNL
                     NILKEGGTGSKSEEIVQPELFPDKYESGTHNTPGIAGLNQGILFIFERGINNIRQHEE
                     ELCQYMIDKLEEVPDIKIYGPKDSKKRASVIALNIGDMDSGEVTFLLDSDYNIATRSG
                     IHCSPLAHTTLGTLKQGAVRFSIGYFNTKDEIDKAVEALKKISKNK"
     gene            complement(22102..23001)
                     /locus_tag="KOU88_003170"
     CDS             complement(22102..23001)
                     /locus_tag="KOU88_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3213026.1"
                     /translation="MSIYGYTIFETVLEQNSFIKAASILNLTPSAVSHAIAKLEIDVG
                     FQLFIRNRNGISLTREAEKILPHIRILLHSNEILEQEINRISRSESGIIRIGTFNSIT
                     INWIPEIMKSFRQEHPNIEIHILQGNYINILEWIETSIVDLAFISNTVLPPHIESIPL
                     HKDRIICVFPKGFVPCNPGYVTIEDIQNMSFVMPKKDYDQEVEKILREYHLNVYSQFH
                     IDTDSAIVAMVEAGFGIAILSELIYKSCVGNVDTYPFVPEHYRVISLAYPNSQYDSFA
                     VQKMKEHIVSYTKEKGFFNFKSF"
     gene            23271..24467
                     /locus_tag="KOU88_003171"
     CDS             23271..24467
                     /locus_tag="KOU88_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK3213027.1"
                     /translation="MVKFAKRMENMKNSANIVRNLFNSMTDPEIISFGGGAPAIEALP
                     VDIVREISNEVLAKNKRGIEALQYSHPYGLKDLREAVAQKLLEPKGVHASPEDIMIVN
                     GGLETMNLICQVFIDPGDVILVESPTFVHCVEIFEMFQAKCIAVDMDEHGIIPEDIER
                     KIQKHHPKMVYVIPTFHNPTGRTLTTERRKILAGIGSKYDVLILEDDPYRDLRYSGEE
                     LPPIKAFDQTGHTILANSFSKIFSPGARLGYVLAEHAIIERLLDAKTATNSHTSAISQ
                     VLCAEFFNRGYFDEHLKNIRDIYRERRDVMIESIDKYLPKGTKRVFPDGGLFTWVELP
                     ENINTTELLKEAVEHKVAFVAGEGFFTEGGGKGRNCMRISFGNVPPEKIRIGMERLGQ
                     LIASKM"
     gene            24535..25281
                     /locus_tag="KOU88_003172"
     CDS             24535..25281
                     /locus_tag="KOU88_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HBK3213028.1"
                     /translation="MTNKVPNLWNQLENLKKSYKWVDLSREVSPETPHWTGFPAMEVE
                     PFYLLDRGDGFNVNKYTLVTQYGTHVDAPIHFVADRKYLDEYTPMDMVLPLCVIDKSD
                     EVAKNSDYVVTVEDIQAWEKEYGNIPEGAFVAFRSDWSKRPDDSLDNYDSDGNKHFPG
                     WSIEALQYMVEKRNIAAIGHETCDTDAPILSNVSGYQAETYILGENRYQVEFLVNLSE
                     LPAIGAIIFVTFPRIHKASGFTARCFAICP"
     gene            25314..25817
                     /locus_tag="KOU88_003173"
     CDS             25314..25817
                     /locus_tag="KOU88_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBK3213029.1"
                     /translation="MSKKAMFVWCVGLGLLDGIYCILCSYLPHIQNYMWIGFISLPIY
                     FCGGAKLEEMPKYFCCAASGIFWGGLTLVVLDIGFISNIHLNMLVFVTIVVCIACFVH
                     LGVLTENVWKGLFSSCPMMFGGFAAIFSQGLAEWFWVLVTLTLGLIFGCIMASISTPI
                     TKWIDKN"
     gene            26065..26900
                     /gene="panB"
                     /locus_tag="KOU88_003174"
                     /pseudo
     CDS             26065..26900
                     /gene="panB"
                     /locus_tag="KOU88_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
     gene            complement(28418..28993)
                     /locus_tag="KOU88_003175"
     CDS             complement(28418..28993)
                     /locus_tag="KOU88_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GerMN domain-containing protein"
                     /protein_id="HBK3213030.1"
                     /translation="MKNKKIMLVLSILSISIFAVGCTNAQNGSDSSKKETKSNTNVEQ
                     PKEENNTEKEVPNNKAKPTPKEETKTQSATIYSFDVDKTDLIENKVDLNKIDENTLFE
                     ELQKLKVVPESAKLNSFTTKDIDGVKTGILDVSSDFTKSNLGSDAETLMLDSVARTYI
                     KNMNVEQIKITVDGSNYESGHIVLEEGDYLK"
BASE COUNT        10550 a         4048 c         4307 g        10299 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttcttgt tccttttttc
       61 aaggacaagt aatactatac catctttaaa acagtaggtc aatacttttt ttatattttt
      121 ttataaattt ttttcatatt cttttttcag cttctctact acctttttct ctagtctaga
      181 aacagtcatc tgtgatatcc ctagttcttt agctatacta gattgtgttt tatcaaagaa
      241 aaatctatct ttaaaaattt taacttctaa ttcatttaaa gtttcaataa acttattaat
      301 aaaatcttca tactctatac ttccaaagtt accttcttct tttccaatct tatcaataag
      361 agttatatct ttatcctctg aatcatcatt acttgatgaa tccaaagaca ttggttgata
      421 tccataagaa gcctccatag cctctaaaac atcttcttca ctaacgccta tataatcagc
      481 tatatctttt acctttggat gcttcttatt ttcttgttct aatttaatct tcgcatcact
      541 tatctttttg cttaattcct gtattcttct tgggactcta agtgtccata ctttatctct
      601 aaaatacttt tttatttctc ctactatagt tggtgttgca aagctggaga actcaaatcc
      661 tttctcaaca tcatatctat caatagcata aattaatgcc aatgaagcaa cttgatatat
      721 atcttcaaaa tcaacacctt tgtttatata cttcttagct aacaatcttg ctaaatacag
      781 atgtctttca ataagaatat ttctaatgtc tacattttta tttttattat ataaattaaa
      841 tagctctttt gtatccatat ttaggtaatg tgtagcatta gctacatttt tcattaaata
      901 tcaactccta aatatttagt catttttatt tttgtccctt gattatgttc tgattcaata
      961 tctacatcat ccattaaagt tttaattata aacaatccaa gaccactctc ttttggattc
     1021 tctaaatctg gtgtacttat tgagctaaca tcatatcctt ttccattatc ttgaatttct
     1081 atattaattg cattatctaa aatattaaat actatattaa atacatcatc tttactgtgt
     1141 tttattgcat ttgtacatgc ttcagatact gctaccttta tatcttctat atcatctatt
     1201 ggaaaaccca tcttattggc aattccagat gctgttaatc ttattatact aacataatct
     1261 ggatttgtag taatttccat ctttatagtc tcacaagcca aagtttatcc ctccacttta
     1321 aatattttat ctagacctgt tatagtaaaa atctttctta cgttactctt aggatttact
     1381 atgtatatct ctttttcatt tatttttaat ttttttaata cacctatcat agctcctaag
     1441 cctgttgagt ctatataatc taaatcttta agattaatct ttacatctaa catatttttt
     1501 tctattaaag catgtaaatg ttcctttagt ttatctgctg tagaaacatc aagttctcca
     1561 tcaagacaaa cattccaaaa tttattttgt gaatctaaat ttgaatcaat attcatagac
     1621 atgtaaaaac ctcctatttc cttttaataa ttttaaatat atttcctata ctcaatattt
     1681 tattaattac ataaactata tcatctattc cctttgatat tgatgatgca ttttcaacaa
     1741 tatcttgtat atgtctttca ttataatcta caatcttata tgccttttca acaaccttat
     1801 ttatgctgtt tagagtttta gctaaataaa ttgctactat aagagcagag cttcctacta
     1861 acactgctcc aatttgccac ccccatgcat tcattagtta acatctccct catcatcaaa
     1921 gcttttactt attactatat cttcttctga aatctttata tcttcttcat tattatcatc
     1981 atccactaaa tttattattc tctctttaac atcattaaat gtttcatgta gaacttcttt
     2041 tggattttct ttaacatcat taaacttctc ttttgtttct tttcttagtt cagaaccttt
     2101 tttaggtgca aaaaacatac caaatataaa ccctaaaata gctcctaata ataaaaatcc
     2161 acctttttta caacttcttt tattgcacat aacaattact cctttcaatt ttaaattttt
     2221 atctaactac attatacaaa aagaatagga tatttatcct attcttcttc aatatttatt
     2281 ttggcaatcg aaactacatt gacttcatca ttcgtcttca ttaatttaac accacttgta
     2341 actcttccaa acagtgatat ttcattgact cttattctaa taagaactcc atcagaattt
     2401 ataatcatta tctcatcatc ttcgttgacc atatctgcac ctacaattgt accagttttt
     2461 tcagatatat tataagtttt aattccttta ccagctctta tttgacttct atactcttct
     2521 atatttgttc tctttccaaa accattctta cttacaacta acacatctgt acctttactg
     2581 caaaggttca tagacacaac aaaatcttct ttacttaaag ttataccttt tacacccatt
     2641 gctgttctac ccatatatct tatatcattt tcatcaaatc ttatagacat accttcttta
     2701 gttactaaaa gtacttcttg ttttccatct gtaagttcta ctccaataag ctcatcatca
     2761 tctcttaaac ctatagcaat aagaccagat ttatttatat ttttgaactc ttctctctta
     2821 gtctttttaa caataccttt tttcgttgca agtaataaat attcattttc atcattacca
     2881 tcaataggta ttagagtagc aattttctca tctgctgaca attgaagtaa attcactata
     2941 gcagtacctt tagcctgtct cttaccttct ggtatttcat atgcatttaa tttaaatact
     3001 ctacctttat ttgtaaagaa taatagtcta ctatgagtag ttgtagttac caagtgcctt
     3061 acaaaatctt cttctctagt tgtaagtgct gaaatacctc ttccacccct tttttgactc
     3121 ttataagtat cagatggaag cctttttata tatccaaagt gagtaagagt tattgctatt
     3181 tcttcatcac ttataagatc tctcatatct atttcgcctt cagcatgtct tatttctgtt
     3241 cttctctcat cagagtaatt ttcttttatt attgtaattt catcctttat tacatttaaa
     3301 agtaatcttt catcagctaa aatctctttt aatctattta tcttcttgat taaatcttca
     3361 tattcagctt ctatcttatc tctttctaaa cctgtaagtc tttgaagtct catatctaat
     3421 atagcttgtg cttggatttc agttaatttg aatttttcta ttaaacctag cttagcttct
     3481 tgcccagtct ttgaagctct tatcaagctt ataacagcat ctatattatc taaagcaatc
     3541 tttaatcctt ctaaaatatg tgctcttgct tcagctttat ttagttcaaa tttagttctt
     3601 cttgtaacaa catcttcttg atgtttaata taatgatata atatttgttt aagatttaaa
     3661 actcttggct gaccatctac aagtgcaagc attattatac taaaagtatc ttccatttga
     3721 gaatgtttat acaaattatt taatactata ttagcattag catccctctt taattctata
     3781 acaattctca taccatttct attactttcg tctcttaggt ctgatatacc ttctattctc
     3841 ttttctttaa ctaactctgc tattctttca accagtttag ccttatttac ttgataaggt
     3901 atttctgtaa ctattatttg ctgttttcct tttggtagct cttctataaa agctctagac
     3961 ctaactttaa cttttcctct tccagttctg tatgcttctg ctatactttc ttttcccatt
     4021 ataattgcag ctgtagggaa atctggtcct tgaacaaatt ttattaaatc atctacacta
     4081 cactctggat tatctatcaa atatacagtt gcatcaatta cttctgctaa attatgtgga
     4141 ggtattgaag ttgccatacc aacagctata ccatttgagc catttactaa taaattagga
     4201 tatctagctg gcaatactga aggctctttt aacgactcat caaagtttgg tttaaagtct
     4261 acagtttcct tttcaatatc tctcagtagt tctaatgata atttactcat tttagcttct
     4321 gtataacgca tagcagctgg tgaatcccca tcaacagaac caaagttacc atgaccatct
     4381 actaaaagtg ctctagttga aaaatcttgt gccattctta ccatagcata ataaacagca
     4441 gtatctccat gaggatggta cttacctaaa acgtccccaa caatacgagc tgacttcctg
     4501 tatggtttat ctggagttaa atttaactca ctcattgaat ataatattct tctatgaact
     4561 ggctttaaac catctctaac atcaggaaga gcacgtccag ctataacact cattgaataa
     4621 tcaatatacg attttttcat ttcttccgct atttcaatag ggagtatttt gttattttct
     4681 tccatgtata ctaatcccct ctctctatat atctaagttt ctaacaaatc ttgcattttc
     4741 ttctataaat tcttttcttg gagcaacctt atcacccata agcattgaaa atacttcatc
     4801 tgcaattgca gcatcttcta cagtaacttg taataaagtt cttgtctcag gattcatagt
     4861 tgtttcccat aattgctctg cattcatctc tccaagacct ttgtaccttt gaagttcaac
     4921 accatttctt ccaatttcat ctaataagat atttaactct ttatctgagt aaacataatg
     4981 ttccttcttt tgctttgtca ctttatataa aggtggctgt gctgcataaa catacccctc
     5041 atctataaga ggtctcatat atctaaagaa gaatgttaat aataaagttc ttatatgggc
     5101 tccgtctaca tcagcatcgg tcataattat aattttatga tacctagcct tatctatatc
     5161 aaaatcttct ccaataccac aaccataagc tgttatcata ttttttattt catctgaaga
     5221 tagtatccta tctagtcttg atttctcaac attaagtatt ttccctctta atggaagtat
     5281 agcttgacta tttctatctc taccttgttt agctgaacct cccgctgaat ccccttcgac
     5341 taagaatatt tcacttttag atggatcttt ttctgcacaa tctgcaagtt ttccaggtaa
     5401 agatgtactt tctaatacac tttttctcct tgttaattct cttgcttttt ttgcagcttc
     5461 tctagctctt tgtgctctta aagctttatc aactatgatt cttgctgttg atgggttttc
     5521 ttctaggaaa gaccccagtt catcaactgt tacactatca actatacctc tcataaagct
     5581 attacctagc tttgttttag tttgaccttc aaattgaggt tctggtaatt taactgatac
     5641 tactgctgta agaccttctc ttatgtcttc accaagtagg ttaacatcat tttcctttaa
     5701 aaatttattt ctcttagcat aatcatttac agttttagta agagctgctt taaatccact
     5761 taaatgagaa ccaccttcgt gtgtatttat attgtttgca aaagaatata tgttctctgt
     5821 ataaccatct gtatattgca tagctagttc aacaaaacaa tcatcaacct ttttatctat
     5881 ataaactatg tcatcatgta taccagttct agatttattt aaatacttaa tgtattctac
     5941 caaaccacct gtatagtgaa attcttttct tttttcttgt ccttctcttt tatcttcaaa
     6001 tactattttt attcctttat tcaagaaaga aagttctcta agcctatact ccaatgtttc
     6061 atatttaaac tctatttcat caaatattgt ctcatctggc ataaattgaa tcattgttcc
     6121 tttatcttga gattctccaa ctacttcaag cttagatgtt ggcaatcctt tctcatatgt
     6181 ctgcttatat atctttccgt ttaaataaac ctctgctacc atccattttg acaatgcatt
     6241 aactacagaa acaccaactc catgaagacc tccagatact ttatatcctc cgcctccaaa
     6301 ctttcctcct gcatgaagat tagttaatac tgtttctaaa gttgatttac cagttttagg
     6361 atgtatttca acaggtatac ctcttccgtt atcttttact aaaacactgc catcttcatt
     6421 aatagataca tatatgtctg aacaatatcc ttgtaaagcc tcatctatac tattatctac
     6481 aacttcataa actaagtgat gtaaacctct agggcttgta ctaccaatat acatacctgg
     6541 tctttttcta acggcttcta atccctctaa tacttgtatc tgacttgcac cgtattcttg
     6601 tttcatttaa tttcctccat tctctatgct aataacatcg ccattttcaa tattaaatat
     6661 tgtaacattt ttttcatcaa atattttttt atgtgaaact tcagcacttg ttataaacat
     6721 ttgaacattg cttaaattat ttactaaaag tttttgtctt gcttcatcta actcactaaa
     6781 aacatcatct aaaattaata ctggatattc ttcaacttca ttttttatta attctatctc
     6841 tgataacttt aatgatattg aagcagttct ttgttgacct tgtgaaccaa aaagtcttgc
     6901 atctaaatca tttatgaata tatttaagtc atctttgtgt ataccatatc tggtagtctt
     6961 agattctata tcattaggtc tattcgatga caacttggct aaaaatttat tatatactgt
     7021 atctatagta tcttcatcag ttatatttat ttgattttta tatcgaattg ataatctttc
     7081 aactccatta gtcaaattca tatgcatatt ttcagatata ttagctatct tttttataaa
     7141 gtctctacgc aaaatataaa tataacttcc atactttgct aacgtatcat catatacatc
     7201 taataaagct tcatcaacat gtatattttt aagcacccta ctcctttgag aaagtgtttt
     7261 attataattg gtaagatatt tataatattt aggtataatc tgactaatct ctttgtctat
     7321 aaatgccctt ctttctttag gaccctcttt aaccaacctt aaatcctcag gagaaaatat
     7381 aacaacattt aagttgccaa gtagttcttg tatcttttgt aaaggaactt tatttattct
     7441 tatccctttt ttatcttttc caataattag ctctattaga ctatatttat tatattttga
     7501 aaaacttcct ccaatatata agttttcact attaaatcta accatttctt tatctttgtt
     7561 agtcctaaat gattttccaa aagaaagcat ataaatagat tctactatat ttgtctttcc
     7621 ttgaccattt ttaccaacaa gtagatttac tttcccatta aattccagat gcaacttttt
     7681 ataatttcta aaattaacaa gttgcaaact tttaagtttc acaaaaagtt ctcctttttt
     7741 tacaatactt ttattttagt tccttctatt tcaactatat ctcctgattt tatctttttt
     7801 cctcttctta attctatttc atcatttact gtcactaaac cttcttgaat taaaaatttt
     7861 gcatgacctc ctgttgatgc aatctctgct aatttaagaa attgatccaa ctttatatat
     7921 tctgattcta tagttatttc agtcataata gttcctcctt gtcactattt taaacaaatt
     7981 cctattgata cactaaaagt atattatacc ataaatatgc ttataaaagg agttgtctaa
     8041 gattagaaaa attttctaca aaagacaact ccttcatgtc tgctatatat ttgatgatat
     8101 tcttactgga agcagtaagt aaatataatt aacatcatct gttggtttaa ttatacaagg
     8161 atttacattt gtagtaaatt ctataaatat ttcctcatta tctatatttt tcaaaccttc
     8221 gataaaatat ctagaattga aagctatatc taggtaatct ccatctaaat ctatttcaac
     8281 ttcttcatac acatttcctt tttctgtatt agaagtaatt gccattactt tatctcttat
     8341 agataacttt ataagattat ttttttctga ttgagacaat aaagacgctc tctctatact
     8401 atttaaaagt tccttagtat ttaatttaac tctgctgtta tgttctcttg gcaataattt
     8461 tttataatca ataaaatctc cttcaagcaa tcttgtaata atttttgtat cattaattat
     8521 aaaaatagca tttttttcgt taaatccaac tttaacatta tcctctccag aaagcaaact
     8581 atttacatct ataagtgtct ttccaggaat tatgactttt atattttcag ttaaactatc
     8641 aaccgaacaa ctttttacag ctaatctata tccatcaatt gctactaaat ttaagtttct
     8701 atctacaatt tctaaaagtt ctcccattaa aacaggtttt gtttggtcct gtgagatagc
     8761 aaatacagtt tgtttaatca tattttttag gatttcttga ggtatgctat ataaatcttc
     8821 ttcatttaat tctggtaatt taggaaattc ttttgctgca taacctttaa ttttaaatct
     8881 tgaatttaca caatttatgt aaatattatt ttctgaatca gtttctatct caacaaagga
     8941 atctggtaat tttctaatta tatctccaaa tagccttgca tctacaacaa catcaccttt
     9001 ttctatgatt tctgcttgta cataagtttc tattcctatt tcagcatcat atccagtaag
     9061 ttttaattga ccttcttctg tagatataag tatacctttt aataattcta ttgttgtttt
     9121 tccattaata gctttttgag caattccaat tctatttgct aggatttttt gattacaaat
     9181 tattttcaat gtggataacc tcctctggct ttttatatat aaaaataagt taaaatcata
     9241 gtagtaatag tagtaggtgt tgttgataat gttaataagt atgtataaca ttataaatac
     9301 aaagatatta acatgtgtat aagatgttaa tatctttgtt attttagact tgataatttg
     9361 ttaataattt ttgttcaaaa aaagtatgaa caggttattc aagagatata aacatacaat
     9421 tgtgtataaa ttatcccttc aaatctgata taattttgtc tattttagtc ttaatttctt
     9481 cactttcttc tatatcctta gatactttgt catgagcatg aattactgtt gtatggtctc
     9541 tacccccaaa ctcttcacct attttaggaa gggataaatc agtaagctcg cgcgttaaat
     9601 acatagctat ctgtcttgga taagctattg aacgtgttct ttttttagaa ttaaaatctt
     9661 ccatctttaa attgaataca gaagatactt tttcttttat tctgagaaca tttatttctt
     9721 catttttaga agttgttata atatctttta aagcttctgt agcaagatca aaagatatta
     9781 ccctattgct aagagaagaa taagcaacca ctctagttaa tgcaccttct agttccctta
     9841 tgtttgactt aatatttttt gctatatatg acataacctc atttggcaca tctatacgtt
     9901 ctagttgagc cttttttcta agtatagcaa ttcttgtctc aaagtcaggt gcttgaatat
     9961 cagttataag tcccatttca aatctcgatc ttagcctatc ttctagtgta ggtatgtctt
    10021 ttggcggtct atcactagat ataattattt gtttgtttgc ttcatgaaga gtattgaatg
    10081 tatggaaaaa ctcttcttga gttctttctt ttcctgctat aaattgaata tcgtcgatta
    10141 gtaatacatc tacgtttcta tatttattcc taaattcttc gtttttatcg tcttttatag
    10201 agtttataag ttcattagta aatttttctg aagaaacgta aactactttt gagtcttttt
    10261 tttgactaac aatatgatga cctatagcat gcattaggtg agtcttacct aatccaactc
    10321 ctccatacaa aaaaagtggg ttataagctt tagctggaga ttctgcaact gcaacgcatg
    10381 cagcatgtgc aaatctattg ctattaccaa taacgaatgt atcaaatgtg tattttggat
    10441 ttagattggg gtaaagaact ctataattta aatctgtgct atcagaattt aaatcagcaa
    10501 cctctttttc gctcaataca aatttaatat tatatttttt taatgacagt tgactaatag
    10561 catcttcaat taaatgtaaa tatctattct ctaagatatc tttattaaaa tcactaggag
    10621 ccagtaagat taaatcatta agatgtattt ttaatggtac gatgttttta aaaaaggtat
    10681 taaaacttac tgaagttaag tcacctttta ttaattgtag ggttttgtcc cataaagaaa
    10741 ctatatccat aatataaacc tccgaacaga ataattaata ttttccacaa agttattaac
    10801 agaaaagcaa aaatatatat aaattttaca gaataactaa atttatggat aatggtgttg
    10861 ataaattaat aatagtataa attattaaaa aaatatgaaa agatataaac aatatgtaga
    10921 taaagttata aataacataa acatacaata aatggtgatt ataactagag tattgtcagt
    10981 aatcttaaaa gttatacaca aaagtatcca caagctgtga ataatttcta ataagttgat
    11041 aacatttatg cacattatca acaagtatat ttataatatc aaaatatatg tcaaacttca
    11101 atgatttgta actaatttat ccacaatatt aactaattgt tgataaaaat ataaacatgt
    11161 taaaattact ttatttgtgt atataattga aaaaaataat ttagaataaa attaaataga
    11221 tttttactag tattttcaat aaaaaaaata cataatatat atatggtaga ttttgtgata
    11281 taagcgtccc aaaaactcgt tgacaacagt agtaaaagta tttataatta tatgtgttat
    11341 gtttactttg agggtaaagt tattattttt ataaacggaa aataaaatct gaaaggcggt
    11401 gcaaaataat gagtaaaaga acttatcaac caaaaaagag acaaagaagt aaagaacatg
    11461 gtttcagaaa aagaatgaag acgtctaacg gaagaaacgt gttaaagaga agaagagcta
    11521 aaggaagaaa tagattaact cattaattac aaaagggccg ctgcaaaggt ggcctttttg
    11581 tgtaaataat tacaattcat agctgtgttt atggaggtta actatggact ttaataggac
    11641 taaagggttg aaaaaagact ctgattttag aaaagtatat aaacacggca aatcttttgc
    11701 aaacaaatat ttagtaatat atatacttaa aaataaatca gattatagta gagtaggtat
    11761 ttctgtttca aaaaaagtag gaaaagctat tactaggaat agagtaagaa gattaataaa
    11821 agaagcctac agattaaata ttgatgaaaa aattaagcct ggatatgata tagtatttat
    11881 agcaagggta tctagtaagg atgctacttt taaagacata gacaagtcta taaaaaattt
    11941 agttaaaaga acggatattt ctatttaatt gtatgctata aatatggagg ttaatgactt
    12001 tgaataaaat aatttatata ttaaaggaaa taagtaagta tttatcgaat ttatgtattt
    12061 atttagtgag attttatcaa aagtatatat ctcccttaaa gggacctacc tgtagatttt
    12121 atccaacttg ctcacaatat tcaatagagg cgtttaagaa atatggattt gtaaaaggta
    12181 tgtatttaac gataagaaga cttttaaaat gtcatccttt tcatccagga ggttacgacc
    12241 ctctaaaata aaagagagta actattagga ggtataaaaa aattgaatat aataggaaat
    12301 ttcttaggat tgattcttaa ggtaatattt gaatttgtta atcattatgg tatttctata
    12361 atacttttta cgatacttgt aaagattatt ttattaccat taacaattaa gcagactaag
    12421 tcaacaaagg caatgcaaga tatacaacct cgtataaaag agatacaaga aaaatataaa
    12481 aataagccag aaaaacaaaa tgaagaaatt gttaagttat atggagaagc taaaattaat
    12541 ccactatctg gttgtttacc tttattaata cagtttccta tattaatagg attatttagc
    12601 gttttgagag aaccagttgc tcatggcgtt tttgcaaaca aagctgcatt tttagcagct
    12661 gacaatgggt ttttatggat aaaaagctta acatcaccag attatgtatt agcagtattt
    12721 tcaggagcaa gtgcatatgt catgcaaaaa gtaatgacac caaaagatca gttacaaggc
    12781 tctatgaaag taatgacata tgtaatggca ggtatgtctt tctattgggg atttatattc
    12841 ccagcaggac ttacattgta ctggacagta agtaacttat tctcaatagc tcaatattac
    12901 ttaataatga atcctttaaa agctaaactg gctgctaact ctaaggagga aaaagttaat
    12961 gagaaaaagc ctaaaattaa taaaaagtaa gagtaaagag gaagctataa gtaaagttat
    13021 agcagagttg aatttaaaag cagaggatat agaagtagaa atacttgaaa atccaagtaa
    13081 agggttttta ggttttatag gtgctaaaga tggtacttat gaaatttttg ttatcgagag
    13141 ggaagtagat gtagctaaaa attttataga ggtaatgttg aaaaatgcaa atgttgatgc
    13201 caaagtcaat gtatctcaaa aagataattt aatcatggtt gatattgaag gcaaagaagc
    13261 tgcaagttta attggtagaa gaggggaaac tttagattct attcaatttt tgactggatt
    13321 agctcttaat aaaataaata aagattctca tacaagagta cttgtagata tagaaaatta
    13381 tagatcaaaa cgagaagaat ctttaataag atatgctaat aaagttgcta gagaagtagc
    13441 gaaaacaaga aaaactaaaa aattagatta tatgaatcca tatgagagaa gaataataca
    13501 ttcagctctt caaaatgaca aatatgtaat tacatatagt gaaggaaccg atccatatag
    13561 aagattagta attgagtgta aaagataaag tcaacctcct aaacattagg gggttttatt
    13621 ttttaatatt attaaatcat taatgattgg ttaaatgtaa atctatatgt aaaaaattat
    13681 gaattaagag gtgataaatt tgtttataga tgatacaatt gcagcaatag ctacagcacc
    13741 tggagaaggt ggtataggta tacttagaat aagtggagaa aaagctttga aggttgcaga
    13801 agaaatcttt aaatctatgt ctggaaagag tattgaagaa tacaataaga gaacattaat
    13861 atatggaaat atagtggata atgaaaatat aattgatgaa gttttattgg catatatgaa
    13921 aggaccaaat tcctatacag gagaagatgt tatagaaatt aattgccatg gtggatttat
    13981 ttcggtaaag aagatattag aattaatact atcaaaagat gttagattag cagaggctgg
    14041 tgagtttact aaaagagcat tcttaaatgg aagaatagat ttatctcaag cagaggctgt
    14101 aattgatgtt ataaaagcca aaactgatat agctcatgaa gttgctcaaa atcaattaga
    14161 aggttcttta tcaaagaaga taagagaatt gagagataaa gtcactgaga tattagctca
    14221 tgtagaagtt gctatagatt atcctgagga agatattgag catataacat atcaaactct
    14281 taaagaaaaa actgatgaac ttaaaaaaga cattaaaaaa ttatatgata cagctgaaag
    14341 tggaaaaata cttagagaag gcttaaagac ggtaattgtt gggaaaccaa atgtaggtaa
    14401 atcttcacta cttaattcta ttttaggaga gaatagagca atagttactg atataccagg
    14461 aactactaga gatgttatag aagagtttgt aaacataaaa ggtatacctt taaaaattgt
    14521 tgacacagca ggtataagag atactgatga tattgttgaa aaaataggtg ttgaaaagtc
    14581 taaagaatca tttactagtg cagatttgat agtaatggtt ttagatgcat ctagaaagtt
    14641 gtcagaagaa gatatagaga tattagaaaa acttaaggat aaacaaacaa tagtgctgtt
    14701 aaataagaat gatttgaaac aagagattga agaagaaaaa atacttaaat atgtagaaaa
    14761 taatagtata ataaaaatat cagctttaca acaagaagga atagaagaat tgcaagataa
    14821 aatagagtct atggtatata aaggtagtat caaaaataat tctagtttag tagtaacaaa
    14881 ttcaagacat aaagatgcac ttagtaaagc atataaatct gcaacagatg ctttaattgc
    14941 tttggaacaa agtatgccat ttgactttgt agaagtcgat ttaaaaaata tatgggacta
    15001 tcttggatat attaatggtg atacagtaac agaggattta ctagataata tattccataa
    15061 tttctgtatt ggtaagtaat gtacaaaagt aaacttgttt ttattataga gatttttaaa
    15121 aaatttgaag tgtttctcat gaaacattaa ttttgaaaag aaaggaatta taaatgataa
    15181 agtttgaagc aggaaaatat gatgttatag tagtcggagc aggacatgct ggatgtgaag
    15241 ctgctttggc tactgcaaga atgggatata aaactttgat aataacaatg tctttggatt
    15301 ccatagcatt aatgccttgt aatccatcaa ttggagggac tggtaaaggt caattagtta
    15361 aagaaataga tgccttaggc ggtcagatgg gattaaatat agacaagaca tatatacaaa
    15421 gtagaatgtt aaatactgcc aaaggtccag cggtacactc tttaagagca caagcagata
    15481 aatttaaata tcatgaagaa atgaaaaaga cattagaaga tgaaccaaat cttgatatag
    15541 ctatggatga agttgtagaa atacttcatg aaggaaatgt tgtaatagga gttggaacta
    15601 aactaggatg ttcatttaaa tctaaagctg taatattggc cactggagtt tatctgaact
    15661 caaagatata tatgggtgaa gttgcatttt atgaaggtcc taatgcattg gggtatgcaa
    15721 aatatcttac aaatagctta gttgagcttg gtcttagaat gagaagattt aagacgggaa
    15781 ctccagcaag agttcataga gatagtatag acttctctgt aatgtcttta caagagggtg
    15841 atgaaaaagt aactccattc tcatttatga atgaaaatat agaaaaaaaa caagaacctt
    15901 gttatttaac aagaactaca gaagaaactc aaaaagttat actggataat ttaaaaaggt
    15961 ctgctatgta tagtggagta atagaaagta ctggtccaag atactgtcct tctatagaag
    16021 ataaagtagt acgatttagt gataaaacat cacatcaatt atttatagaa ccagaagggt
    16081 taaatactaa agaaatgtat atacaaggaa tttcaactag tttacctttt gaagttcaat
    16141 tagatatgta caaaactata aagggacttg aaaattgtaa gataatgaga cctgcatatg
    16201 ctattgaata tgattgtgtt gacccaactc aactaaaaat aagtttggaa ataaagggtg
    16261 ttgagaactt atttagtgca gggcaattta atggaacttc tggatacgag gaagcagcag
    16321 ctcaagggct tatggctggt ataaatgcag ttagaaagat agaaggaaaa gagccatttg
    16381 tattagaccg ttcagaagct tatataggtg tcttattaga tgaccttgtt actaaaggaa
    16441 ctaacgagcc ttacagaatg atgacatcaa gagcagaata tcgactatat ttaagacaag
    16501 ataatgcaga tatgagatta actcaaaaag gttatgatat aggattagtt aaaaaagata
    16561 gatatgaaag gtttctaaat aaaaaggctg ctgtagataa agaatttgaa agactaaaaa
    16621 atgaaagagt tacaccaaaa gaagtaaata gtttgttaga agaaaaagga gcaacaccaa
    16681 taaaggttgg aatatctcta tatgaatttt taaagagacc agaggttact tacgaattgc
    16741 ttgaagaatt agggaaaggc gctggagatg atgtttcaag agaagttaaa gaacagtgtg
    16801 taataataac taaatatgaa ggttatatag agaaacaatt gaaacaaata gaccaattta
    16861 aaaaacttga gaataaaaag ctggatgaga aaataaatta ttcatctata gaaggtctta
    16921 gattagaggc tagacagaaa ctagatgata taaaacctat ttcaataggg caagcatctc
    16981 gtatatctgg tgtttctcca gctgatatat cagttttact tatataccta gaacaaatca
    17041 gaagaactag aggtggcaaa ggtgaataat atagaacttc tgaaaaacgg gattgaaggt
    17101 tttaatatag atacgaatga cagtatgtta gaaaaattta aaatctatag agagatatta
    17161 gttgactgga ataaaaagat gaatcttact ggaatagaag atgaaaaaga agtgtatata
    17221 aaacattttt tagactctat ttcagctgta aagaatggat atataaaaaa tgggatgtct
    17281 ataatagatg ttggtacagg tgctggtttt cctggaatac cattgaaaat atgtttagat
    17341 agcttagaac ttactttatt agattcgtta aataaaagaa taaacttttt agaggaagtt
    17401 agtagagtac tagagttaga taatattaca tttatacatg gaagagctga agattttggt
    17461 aaaaatgaag actataggga aaaatatgat gttgctacgg caagagctgt tgctggatta
    17521 ccgattctta tggaattttg tgtaccattt gtaaaagttg gagggtattt tatttgctta
    17581 aaaggtccga atgctaattt agagctagaa gaatcacaaa aggctattga tgttttagga
    17641 ttggagtata ttgaaaaaat agatgtagag ttaccagagg tagatttaaa tcataatata
    17701 ttagttttta aaaaagtgat ggaaacacca gttaagtacc ctagaaaagc tggtaaacca
    17761 gccaaaaatc ctattaagta atgaaaaatt tattattggt aagcttaatt atttctcagg
    17821 aaataattaa gcttactgta aaaaaacaaa aataaaggaa ttattaaagt agatgcagaa
    17881 ataaatttgt atgtacatat agagaacaaa aataatttat atctaaaata agagaggtat
    17941 gttatggaag ataaaagagt tatggagata cctatagaag atgtagttcc aaatccatat
    18001 caaccaagaa aaatattttc acaagtttca ttggaggaat tgagcaattc tataaaggta
    18061 tatggtataa ttcaacctat aacagttaga gcaaaagatg gcaaatatga actaattgca
    18121 ggagaaagaa gattaagagc agctaaatta gcagagctta aaaccatacc agcaattata
    18181 aataatatga acgatgaatc ttctgctgtt ctagcgttat tagaaaattt gcaacgagaa
    18241 gacttaaatt tcattgaaga agcaattggt tatgaaaact taataaaaga acatgctttt
    18301 actcaacagc aattagcaga aaaattgggc aaaaatcaat ctactgtagc aaataagctt
    18361 agaatattaa agcttccaaa cgatataaaa atgaagctaa tagagaataa tttaacagaa
    18421 agacatgcta gagcatttct taaactacca agtgaagatt taatgcaaag tgtgttagac
    18481 aaagtcataa aaaatgaatt gactgttaaa aaaacagaaa aattgataca agatgtatta
    18541 gaagaaacta aagttcaaga agagcctgat aaaaaacaga atataaaggg tgctatgagt
    18601 ataagaattt acataaatac tataaagcag gcctttgatg ctatatcaaa tacaggaatt
    18661 gatgctaagt ataatgaaat agataaggga gattatatgg aagttgttgt aaaaatccct
    18721 aaaaaataga gattactgct taccagtaat ctttttttgt aatataagcc ttgtaatata
    18781 aattgattta tagacattat ttatacttaa aaaacaccta ttcaacattt aaaattaatt
    18841 taattcttaa aggggggaac atcatgggca aagttatagc tgtattcaat caaaagggtg
    18901 gagtcgggaa aactacaaca aatgtaaatt taagtgctag cttaggaact ttgggaaaga
    18961 aaatattagt attagattta gacccacaag gaaatacaac tagtggatat ggtattaata
    19021 aaaacgaagt agaaaataca atctatgaaa ttatgttaga tgggttacat attaaagaag
    19081 caataataag tactgaattt gagaatgtag atgtagttcc atcagctact gaactatcag
    19141 gtgcagaaat agagcttaca tctaaaacta atagagagta tattttaaaa aattccataa
    19201 aagcggtaat agatgaatat gattatatat ttttagattg tccaccctca ctggggatgc
    19261 ttacaataaa ttgtttaact gctgtagata gtgttttaat tccaatacaa tgtgaatatt
    19321 atgctttaga aggtgttagt caattaatgg agactatcaa attagtaaaa tcaagattaa
    19381 atgctgatat agaaattcaa ggtgttgttt taagtatgtt tgatggaaga gctaatttat
    19441 caatacaagt agttgaagaa gttaagaaat actttaaagg tagtgtatat acaactttaa
    19501 ttccaagaaa tgtaagactt gcagaagctc caagtcatgg aaaacctgta atttattatg
    19561 ataaaagatg tagagggtct gtagcttatt tggagctagc agaagaattt atagatttag
    19621 aagaggagga atggtagtat ggagaataag tctaaaagaa gtaatagatt aggtagaggt
    19681 cttagtgcat tgataccaga aattaaagga gaaacttcag aaaaagaaat agtcaacata
    19741 gatatagaca aaatatatcc aaacgaagtt caacctagaa agcaatttga tgaagaaaag
    19801 ataaaagtat tgtctgattc tataaaaaat tatggtgttt tacagccaat agtggttaaa
    19861 atggatgaaa ataataaata tatgataata gctggagaaa gaagatttag agcatcaaaa
    19921 cttgcaaata aaaatcaaat acctgctata attaaagata tagatatgaa agatataatg
    19981 gagatagcct taattgaaaa cttacagagg gaagatttaa attcaataga agaggctcta
    20041 gcatataaga gtttaataga gcattacaat gtaactcagg aagaaatatc agaagctgtt
    20101 gggaagagta gacctcatat aactaataca ctaagacttt taaatcttgg acaagatgtt
    20161 atagaaatga tagacagtgg tagaattaca gcaggccatg gtaaggcttt attgagaatt
    20221 gcagataaag atttgcaact tcaaatagcg aaaaaaatag aagaagaaga actttctgta
    20281 agagaagtcg aaaatatagc taaaaaaata tctgaaaata aacaagaaga acctaaaaaa
    20341 tctaaaccta aggatgtatt tattttagat gttgaagata aacttagaaa tatatttgga
    20401 acaaaggtga atatttctaa aggaaagaaa aaaggtaaaa tagagataga atactataat
    20461 gatgatgatt taaatagtat tgtatcaatg cttcttgaat agaacaaaaa tataaaacag
    20521 agaggaagat tgttatgatt tatttagata atgctgcaac tacatatcca aaaccagaaa
    20581 gagtgtataa tgctgtttta gattgtatga aaaattattg tgcaaatcca ggtagagcag
    20641 gccataaact tgctatgaga gctgctaggg agatatatga tacaagagag aatatagcta
    20701 agttgttcaa tgtaagtaat cctatgaata tagtatttac atctaatgca acagattctt
    20761 taaatttagc gataaaaggt gtattacaag aaggagacca tgtaataaca acgtctatgg
    20821 agcataattc agtaataaga cctataaaag cattggaaaa aaggggtatt gaaaatactg
    20881 tagtaaaatg cgattatgag ggatttttag attatgaaga tttagaaaaa tcaataaaga
    20941 ataatactaa attgattgta acaacacatg cgtctaatgt atgtggaact ttaatagata
    21001 taaaaaaagt tggagaaata gctaaaaaac ataatatact atttttagta gatgcatcac
    21061 aaacagcagg tgtttatgat atagacgtaa atgaatgtaa tatagatatg ttggcaatgc
    21121 caggtcataa atgcttattt ggacctcaag gaacaggtat attatatgta agagaagggt
    21181 tgaacttaaa tatattaaaa gaaggtggaa caggtagtaa atcagaagaa atagttcaac
    21241 cagagttatt cccagataaa tatgaatcag gaactcataa tactccaggt atagcaggtc
    21301 ttaaccaagg tatactattt atatttgaaa gaggaatcaa caatataaga caacatgaag
    21361 aagaattatg tcaatatatg atagacaaat tagaggaagt accagatata aagatatatg
    21421 gaccaaagga cagtaaaaaa agagcatcag taatagctct aaatatagga gatatggatt
    21481 ctggagaggt tactttctta ttagatagtg attataatat agcgactaga tcaggaatac
    21541 attgttcacc actagcacat accactttag gtactttaaa acaaggtgca gtaaggttta
    21601 gtataggata tttcaacaca aaagatgaga tagataaagc agtggaagct ttgaaaaaaa
    21661 tttcaaaaaa taaatagcat gagatttaat aatatagaaa taaaaaatgg ggatgtttca
    21721 aaataaaaat ttgaatagag tattgaaatt tttatgtata ttctttaaat aaaaacttca
    21781 atactctatt aattaaatta ctaattttgc taattttcat aaaatctgtt aaattactca
    21841 taaagttata tattttcaaa ggctcaagtc ttgtatgaaa ttacttgttt taatttttta
    21901 tataactatg acttttgcaa tctttttagt tgaaaagcgc cttcaatcat actaaaataa
    21961 taatattaca atgctaaatt attttatcct ctattataat tataaataca aaccggtgtg
    22021 actcatctta tgaaaaaagt attgttcagc gttgataaaa ctgacaatta agtaataaaa
    22081 atattatact aattttactt tttaaaaaga cttaaaatta aaaaaaccct tttcttttgt
    22141 ataacttaca atatgttctt tcattttttg aactgcaaaa gaatcatatt gtgagttggg
    22201 ataagctaaa ctaattacac ggtaatgctc tggtacaaat gggtatgtat caacattgcc
    22261 aacacaactt ttataaatta gttctgataa aatagcaatt ccaaaccctg cttctaccat
    22321 ggcaacaata gcactatcag tatctatgtg aaattgagag tacacattaa gatgatattc
    22381 acgaagaatt ttttctactt cctggtcata atctttttta ggcataacaa aggacatatt
    22441 ttggatatcc tctattgtaa catacccagg attacaaggt acaaatcctt ttggaaagac
    22501 acaaatgata cggtctttgt gaagcggaat agattcaata tgtggaggaa gtactgtgtt
    22561 ggatataaaa gctaaatcca caatagaagt ttcaatccat tctaggatat taatatagtt
    22621 cccttgaaga atatgtattt caatattagg atgttcctgc cgaaatgatt tcataatctc
    22681 agggatccag tttattgtaa tactattaaa agttccaata cgaataatac cactttctga
    22741 acgtgaaata cgattaattt cttgttctaa aatttcgtta ctatgtaata aaatacgaat
    22801 atgaggtaaa attttttcag cttctcttgt taaactaata ccatttctat ttctaataaa
    22861 caattgaaaa cctacatcta tttctaattt tgcaatcgca tgacttacag ctgacggagt
    22921 taagtttaaa atacttgctg cttttataaa actattttgc tctaaaactg tttcaaaaat
    22981 agtatatcca taaattgaca tatgatttac tcctttcctt tagatgagta aaaactcatc
    23041 taaaacgata aaaagattcg ctttatttta taataataat ctactattat taaattataa
    23101 atacaagtga tcatttgcat tttttactca agataataaa aatagtacca cccaaaatac
    23161 aagaattaaa atattatttc tgtttaaaag tgagcggaaa cggaaccttt gctcatctaa
    23221 tctcatataa ttacagacaa atatcaactt gataaaaagg aggaactaat atggtaaaat
    23281 ttgcaaaaag aatggaaaat atgaaaaatt cagcaaatat tgttcgtaat ctttttaatt
    23341 ccatgacaga tcctgaaatt atatcttttg gcggaggtgc accagcaata gaggctttgc
    23401 cagttgacat tgtaagagaa atttctaatg aagttttagc aaaaaacaaa agagggattg
    23461 aagccttaca gtacagtcac ccatatggtt taaaagattt acgtgaagca gttgctcaga
    23521 aattattaga accaaaggga gtacatgcaa gtccagagga cattatgatt gtaaatggtg
    23581 gtttggaaac aatgaatctg atttgtcagg tattcattga tccaggagat gtcattttag
    23641 tagaatcacc aacatttgta cattgtgttg aaatttttga aatgtttcag gcaaaatgca
    23701 tagcagtaga tatggatgaa catggaatca ttccagaaga tatagaaaga aagattcaaa
    23761 aacatcaccc aaaaatggtt tatgtaattc ctacttttca taatccaact ggcaggacat
    23821 tgactacaga acgaagaaaa atattggcag gtattggtag taagtatgat gttttgattt
    23881 tagaagatga cccttatcgt gatttgagat atagtggaga ggagttacct cctattaaag
    23941 catttgatca aacaggacat actattttag caaatagttt ttctaaaatc ttttctccag
    24001 gagcaagact tggttatgtt ttagctgaac atgcaatcat tgaacgatta cttgatgcaa
    24061 aaacagcaac taattctcat acatcagcta tttctcaagt attgtgtgca gagtttttca
    24121 atcgtggtta ctttgatgaa cacttgaaga atattcgaga tatttataga gaacgcagag
    24181 atgtgatgat tgaaagcatt gataagtatt taccaaaagg tactaaaagg gtatttccag
    24241 atggtggttt atttacttgg gtagagctac ctgaaaatat caatacaact gaattattga
    24301 aagaagcggt agaacataaa gtagcttttg tcgcaggaga aggattcttt acagaaggtg
    24361 gtggaaaagg gcgaaattgt atgagaatta gctttggcaa tgtacctcct gaaaaaatta
    24421 gaattggtat ggaaaggctt ggacaactaa tcgcttccaa aatgtaaata attacttata
    24481 taaaatacaa ctttatattt taagatttat aatataacca aaggaggaat acttatgaca
    24541 aataaagtac caaacttatg gaatcaattg gaaaacttaa aaaaatcata taaatgggtg
    24601 gatttgagtc gtgaagtaag tcctgagaca cctcattgga caggctttcc tgcaatggaa
    24661 gtagaacctt tctacttatt ggatagagga gatggattta atgtaaataa atatacacta
    24721 gtaactcaat atggaacaca tgtagatgca ccaattcatt ttgttgccga tagaaagtat
    24781 ttggatgaat atacgccaat ggatatggta cttccacttt gtgtcattga taaaagtgat
    24841 gaggttgcta aaaattcaga ttatgtagta actgttgaag atattcaagc atgggaaaaa
    24901 gaatatggta atattccaga gggtgcattt gtggcatttc gttcagattg gtcaaaaaga
    24961 cctgatgatt ctttagataa ttatgattca gatggtaata agcattttcc aggatggagt
    25021 atagaagctc tgcaatatat ggttgagaag agaaatattg ctgcaattgg acatgaaact
    25081 tgtgatacag atgcaccaat tttatcaaat gtaagtggat atcaggcaga gacatatatt
    25141 ttaggagaaa atcgatatca agttgaattt ttagtaaatt tgtctgagtt acctgcgata
    25201 ggagctatta tttttgtaac attcccaaga atacacaaag catctggttt tactgcccgt
    25261 tgttttgcaa tttgcccata aggttttaac tgttagaagg gagggggaga cagatgagta
    25321 aaaaagcgat gtttgtttgg tgtgttggct taggtctact agatggcatc tattgtattc
    25381 tttgttccta cttaccccat atacaaaact atatgtggat tggttttatt tctcttccaa
    25441 tttacttttg tggaggtgca aaattagaag agatgccaaa atatttttgt tgtgcagcaa
    25501 gtggtatatt ttggggtggg ctaacattag ttgtattaga cataggattt atatccaata
    25561 tacatttaaa catgcttgtg ttcgtaacaa ttgttgtatg cattgcttgt tttgtacatc
    25621 taggtgtatt gactgaaaat gtatggaaag gattgttctc aagttgccca atgatgtttg
    25681 gtggatttgc agcaattttt tctcaaggat tagcggagtg gttttgggta cttgtaacac
    25741 ttacactagg gttgattttt ggttgtatca tggcttcaat ttcaacacct atcacaaaat
    25801 ggattgataa gaattgaaat aaagtagcta ttcaataatt tttaaaaagt taatttattt
    25861 atgaaatata atggtatatt atttcaagat ggtttaaaag gaaaagtttt ttaatacttt
    25921 tccttttaat ttaaaatata aatacatttg ccacataagt gcttctttaa aatctagtat
    25981 tatctttact agatatagga gtaagttgtt ttaccaaatt agttttatat gaagatattt
    26041 acaaaatttt aggaggaaaa aacaatgaaa aatactatac aaacttttaa gaatgctaaa
    26101 agtgaaggaa aaaaactatc tatgcttact gcttacgatt actcaatggc aaaaataatg
    26161 gatgagtgta atataaatgg tcttttaata ggagattcat taggaatggt tgtaaaaggc
    26221 gaagaaaata ctctctctgt tactatagat gaaattatat atcatacaaa agctgtaaaa
    26281 aatggggcaa aaaatgcctt aatagtaagt gatatgcctt ttctatatct taccatgttt
    26341 ctatagaaga tgctgttaaa aatgctggta gacttgttaa agaaggagga gctcatgctg
    26401 taaaattgga gggtggagca aatgttataa agcaaataga aagcattgtg aatgctcaaa
    26461 tacctgtaat gggtcattta ggactaactc ctcaatctgt aaattcattt ggtggattta
    26521 aggttcaagg gattactagt gaagcagcaa aacaacttat tgaagatgct aaattaatag
    26581 aaaaagcggg ggcattttct attgttcttg aaggtgttcc tgcgaaaata tctgagataa
    26641 taactaactc tatttcaatt cctacaatag ggataggagc aggaattaat tgtgatggac
    26701 aaattttaat ttaccaagat atgttaggta tatttgaaga tttcgtacct aagtttgtga
    26761 agcaatatgc aaatgtagga gatataatga aagattcaat taaaaattac atactagaag
    26821 ttgaaacagg ggcatttcca caagaaaaac atagtttttc aataaaagaa tctgaattag
    26881 aaaaattata cgaagattaa ggatgttata agctgtcata tataacaatt tattattata
    26941 tttagagatg gattgtccat cttttctgga taaaaattta tccagtttta tgattataat
    27001 aaccaattgt aaaatatatc taaacaatat attatactat gtagattttt caatgaaata
    27061 acatcagata tttactgaat atttttattt cttatttttt agaggaactt cttttaattt
    27121 aaatataaaa ataatgaatg tgtttatata gtaactgcat atattaatag tttaaaagga
    27181 cactattcat tcgtagaaac ttaaattgat gattttatta aaaaatatgt agaagatatt
    27241 gtaggtttat gtcttcatag aataatgatt atattatatg aatgtgattt agcataaaat
    27301 tagatatatt aaagttgagt gagaagaatc ttgaacaaag ttcttcttac caactttaat
    27361 atatttctat tatacaatct attttttatc attattgaaa ttgtttacaa cttgatttaa
    27421 ctcaattaat atacttccaa cttccatata gagaatttta ctataaacac aagtaataca
    27481 ataggaatgt aattatcact tgattttttt attttttaaa tcccataaca aaacattaag
    27541 tgcaactatt ggagttaaca attgttgtag tataaaagct attaagttat ctatatatta
    27601 tcttcctaaa aaagttttct taacacttta attattattc aaaaactatt taaacaaagc
    27661 tataagagag tttaagctat cactccaata agatttattc tttattttat acatctaata
    27721 tttcaaattc gtaaatttac ttccaattat agaattatac ttgtttcgta tttattcaat
    27781 ttatcttata aaagcttttg ttttgtaaaa atattaattt tatattaaaa caagacttag
    27841 aaactatata cttcttgaaa aaattctaat atagataaat ttaaatatta taaatgaggt
    27901 atttttttaa atgaggaaga taatggtaga taattaaaaa tatattattt tatcatttga
    27961 tatacattta tttattcaaa aactataaaa gaacattaac ttttttagaa gtagaattta
    28021 caactaaaga ttgtaatatt gctattgaat ctaagcatta taaaaaacat tggatacaat
    28081 ttattggtat agcattttca aaatgtcaat atcacttgtt atattactgt aaattgtata
    28141 gattatctta gccttgaaag tatttgtgta tatatggtga ctatgataat tgacaatcta
    28201 gtaaataaga taaagataac attagtagga taaaatattg gtatataaaa gatctaaata
    28261 gaacctgaaa ggtgttgttt caaaattgat tttttataat caaattttta tttctatttt
    28321 tatgtttttg tatgtaaaaa agaaaggaag gagataattc aaatttttat tttgaaccat
    28381 ctccttctat atgataattt ataattgttt caagaaatta ctttaagtaa tctccttctt
    28441 caagaactat atgaccactt tcgtaattag aaccatcaac agtaattttt atttgttcaa
    28501 cattcatatt ttttatgtaa gtacgagcaa ctgaatcaag cattaaagtt tctgcatcac
    28561 tacctaagtt tgactttgta aagtcagagc taacatctaa tataccagtt tttacaccat
    28621 caatgtcttt tgtagtaaat gaatttaatt ttgcagattc tggaacaact ttaagttttt
    28681 gaagttcttc aaataaagtg ttctcatcaa ttttatttaa atcaacttta ttttcaatta
    28741 aatctgtctt atctacatca aaagagtaaa tagtagctga ttgagtttta gtttcttctt
    28801 ttggagtagg tttagctttg ttattaggaa cctctttttc agtattgttt tcttcttttg
    28861 gttgctcaac atttgtattg ctcttagttt cttttttaga tgaatcactt ccattttgag
    28921 cattagtaca accaactgcg aatatagata tagataatat acttaacact aacattattt
    28981 tcttattttt cataaaaatt tctcctctct taaaaactat tcttatatat aattatagtc
    29041 gttatgagca aatatatgaa tacaaaatag taacaaattt aaaaaatgat ttatttaaat
    29101 taataaaact caaaataaac taaattttag tcatttttat gggaaatcat ttaatgtaca
    29161 gtgaaaatat tgtaaaataa aagtagtgtt tttaaaataa atat
//
LOCUS       DAFAZV010000052        29192 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFAZV010000052 DAFAZV010000000
VERSION     DAFAZV010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 29192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29192
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.052"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            449..2683
                     /locus_tag="KOU88_003176"
     CDS             449..2683
                     /locus_tag="KOU88_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3213031.1"
                     /translation="MQNHNYIKMLNKKVEVLSKELDSRNFKLKTLNEIDFFSKIPNRE
                     FMYQYIDDCISKNIHIGIMLLNIDNFKLFNDIYGYLVGENLLITLTQNLLHFIPESKG
                     IVAYLKGEGFLIVLPNVSNKELNNMGATIIESARELKIKLPNEKEIYSNVTFSIGSTI
                     WNGEPNMTTLMLFNQVYSALKKAKSEGKNRYILFDFKDNSFYNKLENDKEFLSEISHV
                     LQTKQIEVFYQPLYNIKNNTIVGCEALARWRHPIKGLLTPDKFIPLFEQFGLITELDL
                     HLFEENCKNIRRWIDNNDVFVPICCNFSRLHFFNPNFPSMLKGITEKYSVSTSNFSIE
                     ITENILIENTNTIIQQLAELRSYGFSVSMDDFGSGYSSFGMLQNLPFDIIKIDRIFLS
                     HNLNDFKNTTILYSIINIARALGMLTVCEGVETEQHVEFIKSINCDIAQGYYYAKPME
                     CKEFEKLLSKENNSEKMFIKYSDIGKSLIEKIFDGFFIMQDMKKLRANVTEDIQWFDF
                     YNKTEITSFPKVIEHFEKHIKGKKFSILYKSITPHNTESDSLLISGEAVLSDEASEHQ
                     KYSNFYFSANCIISENKLLLAKLHLDLIKTAGYINEFESYSIPKMTNTHLDESNILSQ
                     FYSMLPVGIIRYDLFGDMIITYMNEEMFDIIGYTKEQFFGEMGGNLRAIVHPNDLDFV
                     YKKSLDMIDTNKIEPFLYRFIKRDGQIVTVMYTQCNLSAIDGRSIAQGMYVDVNKIKN
                     LTKI"
     gene            2714..3559
                     /locus_tag="KOU88_003177"
     CDS             2714..3559
                     /locus_tag="KOU88_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3213032.1"
                     /translation="MFKEIFLRTFPGFLIIRDSNYRIIFINDNLKNLIKSYMQDNPLG
                     MTNIEIAKKLPDNIAKFFTDSHNIQLDWEKNYPYDKISNWILEFKKDTTSYWNVLEYK
                     VDVDEKTYIITMANDITKLYEENKRNLHYSITDPLTGAYNRKYLNDRFDIFIGDYIVL
                     IDLDNFKMINDYEGHNVGDKILCDFVSLLNKELINSTSIIRLGGDEFIVIFSSDVDKN
                     YVYSQLEALRENFLKVFSKYKYLSFSYGVDTVKRNLKLTIVELDKKMYKNKEKNKKKF
                     DKNDY"
     gene            3799..5532
                     /locus_tag="KOU88_003178"
     CDS             3799..5532
                     /locus_tag="KOU88_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBK3213033.1"
                     /translation="MSILLKKAPKLAKHIITSFYINRDIDEVLKYLCENVTWIGPGEQ
                     EFLTSFNEIKNYFYAGQDEIPSCDINNDIFETVSEDENRCMVLGRYTVRTKENAQMIL
                     EVNQRCTFEIIEDRGKLLIKHMHISNPYGEMQLDEYFPTKIGTQSYDYLQRLLKEKTE
                     VIEMITNNINGGLKGSNDDSTYSFFYVNEGLPKILGYTYDEFMEMSGGSAVGAVYPPD
                     LPKALEDCERCFAKGPTYSSEYRIRKKDGTLMWVLDSGMKSLNSDGIVKINSIITDIT
                     QLKNIESELKLERERYRIALQNITDIMFEYDIENDTLIKYQRVEIDKKIELENFETKN
                     YSKLLESGKIIHLDDIGKLLEVLHGNLRETIEIRQVNSLTKNEWRWIRVQCSVIYDSD
                     HNPIKTIGVLKDITEDKSKLESLINQAQRDPLTQLYNQRVSQNLIEEYLCSSDSKNND
                     ALLVIDIDDFKTVNDTFGHLEGNEVLVAVSKILLHNTHDKDIVARIGGDEFTIFIKSL
                     TKDLIIKITNDILNDASKIKVKDNHKITLSIGIAFTDDSTKLYKDLFSKADKALYLSK
                     ADGKNCYSTYE"
     repeat_region   5924..6614
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=5989..6017
                     /rpt_unit_seq="atttacataccacttagttaatataaaac"
     gene            complement(6894..7046)
                     /locus_tag="KOU88_003179"
     CDS             complement(6894..7046)
                     /locus_tag="KOU88_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213034.1"
                     /translation="MDNFLQGVLASLVASLIVYLNSKLFKKVKSHSGRSDFSFELKIK
                     FKKNKH"
     gene            8170..9525
                     /locus_tag="KOU88_003180"
     CDS             8170..9525
                     /locus_tag="KOU88_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3213035.1"
                     /translation="MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSK
                     GVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSI
                     IILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKT
                     DGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATGLSQVFSTIFFLIHFLRK
                     NSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSV
                     INYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICM
                     AFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVI
                     SLGRGLVIVVFSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKV
                     A"
     gene            complement(9643..10311)
                     /locus_tag="KOU88_003181"
     CDS             complement(9643..10311)
                     /locus_tag="KOU88_003181"
                     /EC_number="6.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphthine--ammonia ligase"
                     /protein_id="HBK3213036.1"
                     /translation="MKEVLKLADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTIS
                     EEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFEKALIKAKNMGATICAY
                     GDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGE
                     EFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGY
                     LEIK"
     gene            complement(10378..10806)
                     /locus_tag="KOU88_003182"
     CDS             complement(10378..10806)
                     /locus_tag="KOU88_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBK3213037.1"
                     /translation="MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVG
                     AIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTL
                     VSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN"
     gene            10913..11506
                     /locus_tag="KOU88_003183"
     CDS             10913..11506
                     /locus_tag="KOU88_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBK3213038.1"
                     /translation="MNFCYNCSIDFGGDFMYTNFNIDFNNFNKKENAIKFMLMGVLLI
                     ILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVL
                     IIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGIC
                     LILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY"
     gene            11625..12560
                     /locus_tag="KOU88_003184"
     CDS             11625..12560
                     /locus_tag="KOU88_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893027.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBK3213039.1"
                     /translation="MDKFKYAFDNKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDG
                     SLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEIMLKKWPHAKYIGYFQAYTNTYA
                     PLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHD
                     STSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVD
                     GIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKR
                     DELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV"
     gene            complement(12831..13775)
                     /locus_tag="KOU88_003185"
     CDS             complement(12831..13775)
                     /locus_tag="KOU88_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HBK3213040.1"
                     /translation="MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLF
                     FGFIVLGVYSSIRTPQILKINKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVL
                     LYTSPLFLAIFSKLCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGV
                     LSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSC
                     MLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLF
                     GVMLMLISAVVALNLSYDEIRIFCKSNKLKQIEKTESI"
     gene            14093..15523
                     /locus_tag="KOU88_003186"
     CDS             14093..15523
                     /locus_tag="KOU88_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3213041.1"
                     /translation="MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKE
                     DILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGHLE
                     FTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPII
                     NTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESEL
                     FGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGS
                     LKNKKVDIRIISATNVDLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKY
                     YFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPN
                     ILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFG
                     SSYKVAKHLEISQSKANRLIRKYTNT"
     gene            15723..16307
                     /locus_tag="KOU88_003187"
     CDS             15723..16307
                     /locus_tag="KOU88_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc dependent phospholipase C family protein"
                     /protein_id="HBK3213042.1"
                     /translation="MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYK
                     LKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSE
                     RWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMN
                     DLKFSAYTCNSVINYILDSILSNTIKSYHIANCG"
     gene            complement(16411..17190)
                     /locus_tag="KOU88_003188"
     CDS             complement(16411..17190)
                     /locus_tag="KOU88_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK3213043.1"
                     /translation="MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRI
                     FKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQL
                     YFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIEL
                     YLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDIC
                     MLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS"
     gene            complement(17247..18503)
                     /locus_tag="KOU88_003189"
     CDS             complement(17247..18503)
                     /locus_tag="KOU88_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011591286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBK3213044.1"
                     /translation="MKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGD
                     NKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESF
                     FVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMF
                     NESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTI
                     RITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKN
                     LTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVS
                     EQTAVEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIF
                     NGDRRKIRLRATRDLLNELRIQLEKL"
     gene            18761..19660
                     /locus_tag="KOU88_003190"
     CDS             18761..19660
                     /locus_tag="KOU88_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBK3213045.1"
                     /translation="MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKK
                     DIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKM
                     LRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEKAV
                     RKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEE
                     VVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIP
                     RSAAARGIKYSELLDKLIEYSLN"
     gene            19684..21132
                     /gene="ddlR"
                     /locus_tag="KOU88_003191"
     CDS             19684..21132
                     /gene="ddlR"
                     /locus_tag="KOU88_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator DdlR"
                     /protein_id="HBK3213046.1"
                     /translation="MIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELS
                     QLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKK
                     ANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQG
                     YKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTA
                     IKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPEN
                     RYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGM
                     RIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKF
                     NFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNS
                     GFDTLRLGFSRLSFEDIEIGIKIIGETINEMF"
     gene            21191..21997
                     /locus_tag="KOU88_003192"
     CDS             21191..21997
                     /locus_tag="KOU88_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBK3213047.1"
                     /translation="MNLILGDNMSKKSKRRKINKLKLTIVITVLFLALLSIYEMLFSN
                     PNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGK
                     SMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEK
                     IKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDV
                     TPKVSKVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK"
     gene            22023..23942
                     /locus_tag="KOU88_003193"
     CDS             22023..23942
                     /locus_tag="KOU88_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_071223118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK3213048.1"
                     /translation="MNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKST
                     LLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQ
                     EILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSG
                     GQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLD
                     RVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVRRGAQ
                     ARSTKQKARLQRFDELINRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVID
                     NLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHM
                     NIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHL
                     LKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFA
                     YEGNGKIHIYTGNYSDYLIYREIQGIEFEESKKESVKKDDSTTLKKEKPKNDKKLKFS
                     YNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYER
                     WEYLNNLADEIANNK"
     gene            complement(24184..24531)
                     /locus_tag="KOU88_003194"
     CDS             complement(24184..24531)
                     /locus_tag="KOU88_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PqqD family protein"
                     /protein_id="HBK3213049.1"
                     /translation="MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRK
                     LKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNH
                     IEVNCHYIERLDI"
     gene            complement(24518..26446)
                     /locus_tag="KOU88_003195"
     CDS             complement(24518..26446)
                     /locus_tag="KOU88_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide transporter, OPT family"
                     /protein_id="HBK3213050.1"
                     /translation="MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAI
                     FAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASG
                     FIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAI
                     SETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEV
                     NPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQM
                     DVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQM
                     ILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSG
                     MTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSK
                     NEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSL
                     PWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKE
                     KEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLV
                     VLTALPIVLSKVKNNEQE"
     gene            complement(26857..29046)
                     /locus_tag="KOU88_003196"
     CDS             complement(26857..29046)
                     /locus_tag="KOU88_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HBK3213051.1"
                     /translation="MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVF
                     KMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVR
                     QSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDI
                     EKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDL
                     EFVCKEEEKVLLEDFNNNQYEIPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELD
                     EVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLN
                     YLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTIST
                     SGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVG
                     ASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERL
                     KGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPI
                     GAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEHNKLMYRTGDLVRWLDDGNLD
                     YIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEED
                     SGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKRALPE"
BASE COUNT        10911 a         4142 c         3780 g        10359 t
ORIGIN      
        1 aaatacaaga ataaacttaa ttttaataac taaaattaat tatgcaaaat tattaatatg
       61 gtattaaatt atgtataaaa agttaattat gaataaaata attatgcctt tgaaaaatca
      121 ttaaacttaa aattaattat aaaaaaactc taccttacta actatacagc tcacaatcta
      181 tctatttatg aaaaaatatg atataattgc attcaaaaag gaaatctttc aatatactag
      241 aatttaagca ttaactaatt ttatctaata ttattactaa actaaaaaat atttgtattt
      301 gtagcattgg agcaagtaac ttaatgtata ttcattttaa atacttattt aaaatttagc
      361 atttaaatta tttacaaatt aacatttaaa tacttctagc ataaatacag ttgtcatcaa
      421 aatttaaagt atcttatgga ggaataccat gcaaaatcat aattatataa aaatgttaaa
      481 taaaaaggta gaagtattat ctaaggaatt agatagtaga aattttaaat taaaaacctt
      541 aaatgaaata gatttttttt ctaaaatacc aaacagagaa tttatgtacc aatatattga
      601 tgactgtatt tcgaaaaata tacatatagg aatcatgtta ttaaatatcg ataactttaa
      661 attatttaat gatatatatg gatatctagt cggagaaaat ttattaatta ctctaactca
      721 aaaccttttg cactttattc cagaatcaaa gggaatagtc gcttatttaa aaggagaagg
      781 ttttttaatt gtacttccaa atgtatcaaa taaagagtta aataatatgg gtgcaactat
      841 tatagagagc gcccgagaat taaaaataaa acttcctaat gaaaaagaaa tatactccaa
      901 tgttacattt agtattggca gcactatctg gaatggtgaa ccaaacatga ctactttgat
      961 gcttttcaac caagtatata gtgctttaaa aaaggctaaa agtgaaggta aaaatagata
     1021 cattctattt gattttaaag ataatagttt ttacaataaa ttagaaaatg ataaggagtt
     1081 cttatcagaa atatcacatg ttctacaaac taaacaaatt gaagtatttt accaaccact
     1141 ttataatata aaaaataata ctatagttgg atgtgaggca cttgcaagat ggagacaccc
     1201 tattaaagga cttcttactc cagataaatt tattccttta tttgaacagt ttggtctgat
     1261 aacggaatta gatttgcatt tatttgaaga gaactgtaaa aatataagaa gatggattga
     1321 taacaatgat gtttttgttc caatttgttg taacttttct cgtcttcatt tttttaaccc
     1381 taattttcca agtatgctaa aaggtattac tgaaaagtac agcgtctcta catcaaattt
     1441 tagcattgaa ataacagaaa atatattaat agaaaataca aatacaatta ttcaacaact
     1501 agctgaactt cgttcttatg gtttttctgt atcaatggac gattttggtt ctggatattc
     1561 atcttttggt atgttgcaaa atctaccttt tgatataatc aaaattgata ggatattttt
     1621 atctcataat ttaaatgatt ttaaaaatac aaccattttg tactctataa taaacattgc
     1681 aagagctctt gggatgctta cagtatgtga aggtgttgaa acagaacaac atgtagaatt
     1741 tattaaaagt ataaattgtg atatcgccca aggttattat tatgcaaaac ccatggagtg
     1801 caaagaattt gaaaaattac tatctaaaga gaataattca gagaaaatgt ttataaaata
     1861 ttctgatata ggaaaatctt taatagagaa gatatttgat ggatttttta ttatgcaaga
     1921 tatgaaaaaa ctaagagcta atgtcactga agacattcaa tggtttgatt tttacaacaa
     1981 aactgaaatt acatcttttc ctaaagtaat agaacatttt gaaaaacata ttaaaggtaa
     2041 aaaattttct attctttaca aaagtataac cccacataat actgaatcag attcattatt
     2101 aattagtgga gaagccgttt tatcagatga agcttctgaa catcaaaaat atagcaattt
     2161 ctactttagt gcaaattgta taatttcaga aaataaatta ctcttagcaa aattacattt
     2221 ggatttaatt aaaactgctg gctatataaa tgaatttgaa tcatattcaa tacctaaaat
     2281 gacaaataca catcttgatg aaagtaatat tttatcacaa ttttattcaa tgttgcctgt
     2341 aggtataatt cgctacgatt tatttggtga tatgattatt acttatatga atgaagaaat
     2401 gtttgatatt ataggttata caaaagaaca gttttttggt gagatgggcg gaaatttaag
     2461 agcaattgtt catccaaatg atttagactt tgtttataaa aaaagtttgg atatgattga
     2521 cacaaataaa attgaaccat ttttatatag attcataaaa cgagatggtc aaattgtcac
     2581 agttatgtat acacaatgta acctttctgc aattgatgga aggtcgattg cccagggtat
     2641 gtatgtagat gtaaataaaa taaaaaattt aacaaaaatc tagtacaaag tattttattt
     2701 tggagaaatt aatatgttta aagaaatttt tttaagaact tttccaggat ttctaattat
     2761 aagagattct aactacagaa ttatatttat aaatgataat ttaaaaaatt taattaaaag
     2821 ttatatgcaa gataatccac ttggaatgac taatatagaa atagctaaga aactccctga
     2881 taatattgct aaatttttta cggattctca caatattcaa ttagattggg aaaaaaatta
     2941 tccttatgat aaaatttcaa attggatttt agagtttaaa aaagatacta caagctattg
     3001 gaatgtttta gaatataaag tagatgttga tgaaaaaacc tacataatta ctatggccaa
     3061 tgatataaca aaactctatg aagaaaataa gagaaatctt cactactcaa ttactgaccc
     3121 attaactgga gcatataata gaaaatattt aaatgataga tttgacatat ttataggaga
     3181 ttatattgta ctaattgact tagataattt caaaatgata aatgactatg aaggtcataa
     3241 tgtaggagac aagattttat gtgattttgt ttcactttta aataaagaat taataaattc
     3301 tacttctatt ataagattag gaggagatga atttattgtt atattctcta gtgatgttga
     3361 caaaaattat gtttattcac agctagaagc cttaagagaa aattttttaa aagtattctc
     3421 taagtataag tatctttcat ttagttatgg tgttgataca gtaaaaagaa atttaaaatt
     3481 gacaatagtt gaattggata aaaaaatgta taaaaacaag gagaaaaaca agaaaaaatt
     3541 tgataaaaat gattattaat attgttattt taaaataaat taaaattatc tttctttttt
     3601 taaacttgta cattagttta taaatatgta tctatacaag atattgacat taagtactga
     3661 agcatatatt gtttcagttc ttttttgtta aaattaactt atttaacaaa gatatcatag
     3721 tttaacaaag cttttaattt aaatatattg atgtataata taattaaaat ataatagcaa
     3781 aaagaaagga ggaatatcat gagcatactc ctaaaaaaag cacccaaatt agcaaaacat
     3841 attataacaa gtttttatat aaatcgggat attgatgaag tattaaaata cctttgtgaa
     3901 aatgttacat ggatcggacc aggagaacag gaatttctca cttcttttaa tgaaataaaa
     3961 aattattttt atgcaggtca agatgaaatt ccttcttgtg atataaataa tgatatattt
     4021 gaaactgtaa gtgaagatga gaatagatgt atggtattag gaagatatac tgttcgaact
     4081 aaagaaaatg ctcaaatgat tttagaggta aatcaacgtt gtacatttga gataattgag
     4141 gatagaggaa aattattaat aaagcacatg cacatatcaa acccttatgg tgaaatgcaa
     4201 cttgatgaat actttcccac taaaattgga actcaaagtt atgattattt gcaaagatta
     4261 ctaaaagaaa aaacagaagt tattgaaatg attacaaata atatcaatgg tggcttaaaa
     4321 ggtagcaatg atgatagtac atactcattt ttctatgtca atgagggatt gcccaaaata
     4381 ttaggataca catatgatga gttcatggaa atgagtggtg gttcagcagt gggtgctgta
     4441 tatccaccag acttacctaa agcactagaa gattgtgaac gatgttttgc aaaaggacct
     4501 acatattcat ctgaatatag aatccgaaaa aaagatggaa cattaatgtg ggtattagat
     4561 tctggaatga aatcgttaaa tagtgatggc atagtaaaaa ttaatagtat tattactgac
     4621 ataacccaac taaaaaacat agaatctgaa ctaaaattag aaagagagcg atatcgtatt
     4681 gctttgcaaa atattacaga tatcatgttt gagtatgata ttgaaaacga tacccttata
     4741 aaatatcaac gtgtagaaat tgacaaaaaa attgaattag aaaattttga aacaaaaaat
     4801 tactccaaac tattagaatc tggtaaaatt attcaccttg atgatattgg aaaactacta
     4861 gaagtacttc atggaaatct tcgtgaaaca attgagataa gacaagtaaa ttcattaact
     4921 aaaaatgaat ggagatggat tcgtgttcaa tgttcagtta tatatgatag tgaccataac
     4981 cctatcaaaa caataggcgt tttaaaagac ataactgaag ataaatctaa attagaaagt
     5041 ttaattaatc aggctcaacg tgacccacta acacaattat ataatcaaag agtatcacaa
     5101 aatcttattg aagagtatct atgtagttct gattccaaaa ataatgatgc tctattagtt
     5161 attgatattg atgattttaa aactgtaaat gatacttttg ggcatctaga gggaaatgaa
     5221 gttttagttg ctgtatcaaa aatactatta cataacacac atgataaaga catagttgct
     5281 cgaattggtg gagatgaatt tacaatattt ataaaatcat taacaaagga tttaataata
     5341 aaaattacta atgatatttt aaatgatgcg agtaaaataa aagtaaagga caatcataaa
     5401 ataacattaa gtattggtat tgccttcact gatgattcaa ctaaattata taaagattta
     5461 ttttctaaag ctgataaagc tctttatcta tcaaaagcag atggcaaaaa ttgttatagt
     5521 acatacgaat aataaagcta tttatacgac caagaatgaa cctttaaatt taatttcata
     5581 gtctaacaat caaagagttg aagctaatct tatagctagt caactagttc ctagaaaaaa
     5641 tttagacaat atatttattg atactgctca tttttctaaa gagcaaattt atataaaaaa
     5701 ttaaactttt atgtacatac agatactaat gataaacagt tatcattagt atcttctatc
     5761 ttaaaacaaa atgataattt atctatataa aaaagtgctt tgttgacaga gttcactttt
     5821 ttatataggt acagaattta agtataaata catgttttat tctatacatt ttagttaatg
     5881 taaaatttct tgattgtact ctctaacttt tcaacattat actatttata taccacttgg
     5941 ttaatataaa actattatta tagtgtcgtg tggagggcgg tgtgacttat ttacatacca
     6001 cttagttaat ataaaactgt tttctgaatc tttttttgta tctataatat ttttatttac
     6061 ataccactta gttaatataa aacaaatcct aattgggtag ttatccaaaa gactataaca
     6121 tttacatacc acttagttaa tataaaacct agcttttatt tcctctgctg tcttatcaac
     6181 attattattt acataccact tagttaatat aaaacttgaa tttgtaaata gttagttata
     6241 aaaattaaaa gatatttaca taccacttag ttaatataaa accacacatc tgatactaaa
     6301 aaatataatg ctaaagataa tttacatacc acttagttaa tataaaactt gatgttgtaa
     6361 tatgtccaga aaaaaagttt aaaactaatt tacataccac ttagttaata taaaactcat
     6421 tgtactcgtt aagtttattt gtgaaaaaat ctaatttaca taccacttag ttaatataaa
     6481 acttacagta acaaaaaaat tagatgatgt tgacaatgat ttacatacca cttagttaat
     6541 ataaaacgat ttttctgctt cgactggtgt tattgagact tttttattta cataccactt
     6601 agttaatata aaaccccaaa ataaactggg cattttcaat gcttacacat gtgcaactct
     6661 cttaaatttg cagtgaacca tgagtagtgc aaatgataaa gcttatcaca tgccctcaac
     6721 accttatatt tcaagcatta agccctactt tgtaacaaat atcgctcact gcaaaactat
     6781 ttacattttt attatatcat aaatatatta tttttgaata tctgtaccaa tttgtggtat
     6841 aataaaaaca agaagaacta caatctattt agacatagag tgaagttcaa atactaatgt
     6901 ttattctttt tgaacttgat ttttagttca aaactaaagt cgctcctgcc agagtggctt
     6961 tttacttttt taaataattt actatttaag taaactatta aactggcaac taaacttgct
     7021 agtacacctt gtaaaaaatt atccatacat actcacctcc cttctataca ttgggaggat
     7081 aatcttttgt atgaactcca ctctataaat tgtagattac atcttcttgc taaaaatgtt
     7141 atagcatata attcttacat attttaccta tatattactt ttctaaagat tcgtctatat
     7201 atttctgtat acatctactc tatcctcgat ttgttacaac cccaatcaaa aaagtagttc
     7261 aacttctaag ttttatacaa agcaggaaac tcaattatta ttagaaaaat caaaaaatac
     7321 tcctataggt ataccaattt ttttgatgct aactcttgga ttacgttttg gtgaagctgt
     7381 atcacttata tggtcagatg tagaccttga taaaaaatct cacatgtaaa tcaaacatta
     7441 gtttatgtat acaataaaat aatcttcaaa ggccctaaaa cccctagatt caaaagaaga
     7501 ttatttgttc ctgatgaact tataagtttg tttaaagggg aaaaattaaa acaaaataag
     7561 ttaaaattac agggtatatt gaaaaatgaa tttgatttga tatgcttaaa taaaagattc
     7621 aacccgtgag ttcaaccaac ttttgttgtt cattttaaaa aactattaag agataataat
     7681 cctagagata taaaagtaca tgaattaata catgcaaatg cgactttgat attactttca
     7741 ggtactaaca taaaagctat ttataaaata ttagtacatg cagatataaa aatagctatg
     7801 aatatatatt ccatattctc acttattaga tgaaatgaat aaagaaacat ctgaaaatat
     7861 aagcaaaata ctattcaaat aatgttcagt tttatgtcaa ttaaatgtca ctcaaagtgc
     7921 tttttttcca tttgtcagtt aaatgtcact taaagtacct ttttcctatt tgtcagttaa
     7981 atgtcagtaa tatataaata agatatattt ataagaccct taaaatcact attatttaat
     8041 aaaatttata attatatact atttgctgtt gacattggta ttataccata gtttatcatt
     8101 tatattagaa taaaattatt aattaatagt ttcgtaattt tataatagat ttacagggag
     8161 tgataataaa tggatacaaa aatatctata aacgaaaaca tgagtctagg taaaagattt
     8221 tttaaatacc tagcaccatc tgtagttgca atgtgggttt tctcactata tacaatggtt
     8281 gatggaatat ttgtaagtaa aggagttgga gaattagctt tagctgctgt caatatatca
     8341 atgcctttta ttaattttat atttgcagtt tctctattat tttcaactgg tgcatctacc
     8401 ataattgcaa tctatctggg gaaaaaagat attaaatctg ctaacgaagt cttttcattt
     8461 aacttagtat caataattat attatcaata attatattag ctataacttt ttttaattta
     8521 gatagattag cactattttt aggagctaca gaatctacaa ttggtatggt taaagattat
     8581 ttaggaataa taatattttt taacggattc tttatagtgt cttattcttt agaagttata
     8641 ataaaaactg atggctttcc aatattagct actgttggtg taataatatc tgctcttaca
     8701 aacatcatac ttgattactt gtttgtaatt gaatttggat ggggtgtaaa aggtgctggt
     8761 attgcaactg gtttgtctca agtcttttct actattttct tcttaataca ttttttaaga
     8821 aaaaactcta ctttgaattt ttcaaaattt agaattgatt ttaagacact tagaaaaatt
     8881 gtatttatag gttttcctga ttcaactact gaattaagtt gcggtatagt tgttttactt
     8941 tttaacttaa gtcttactaa atatattgga gaaaatgctc ttatttatta tagtgtcata
     9001 aattatataa atacattagt acttatgact atgatgggta taactcaagg tatgcaacca
     9061 cttactagct tttattatgg tgcaggaaat atagataatg taaaaaaatt attaaaaatg
     9121 gggataaaag ccacaataat agcatcagtt gctgtatttg caatttgtat ggctttttca
     9181 ggaccaatag tctctttatt tatacatcca gaagaaacaa tgctattcaa tgaaggagtt
     9241 cgtgtattta aaatattctc tatatctttc ttattggtag gaattaatgt aataatttct
     9301 ggattctttg tatcagtaga aaaaccatca atttctactg ttatatctct tggtagaggg
     9361 cttgtaatag ttgtttttag tctaatttca atgatactaa tatttggtgg acaaggaata
     9421 tggatgacta ctattgtttc tgagtttata tgtcttattt tatctttagt ttttctaaaa
     9481 aagaattttt ctacattaga ctctaatcta aataaggttg cttagatgat aagagtagca
     9541 atatatgaaa atatctaaat aaaaaatacc tattatacaa tcttgcaaat attaaacctt
     9601 tgcaaaaatt aggattatat aataggtatt ttatttatgt aattatttta tttctaaata
     9661 tccatagcca tcttttatta aagttccttt tacttcatat tctacaggtt ttttaaatat
     9721 tggaccatct acgacaaatg tatgatactc tccatgttct ccacatgggt ctgcaccagc
     9781 attttttatc ttctccacaa gttctctagt taattttttt cctaaaaatt cctctcctaa
     9841 gtgctttaag tttacttttg ttacaacact acaaaatcca ctgtctataa attcatatac
     9901 taaatcctct ctactctctt gccataatgg taaatctact ttcataccaa ctgcttcaca
     9961 tctatcagta tcccattttc tatgactttc tatatctata tctccatatg cacatatcgt
    10021 tgctcccatg tttttagctt ttattaaagc cttctcaaag ctctcttcat atccttctac
    10081 accacactca gcaactaata aaggtaatcc tatattgcta cttacttgct taagcatatt
    10141 atattctaaa ttatgtgtcc atgactttcc atgttcttca cttatagttg tcaagagtgc
    10201 cacaggctta tatccttttt tcaacattcg atttaatgct aatatactat ccttaccacc
    10261 actaaatgac attacaaatt tttcatcagc caattttaac acctctttca tctaactttg
    10321 ttttattaac ataattatac caaatttttg agttgcatag caaattatat taaattgtta
    10381 attcactata aagaatgtcc ctaatattaa aagtataacc cctatgtatt tgtataaatg
    10441 cattgtttct tgtcccaaaa ttacgctatc aataaaaaat ccaactaaaa cttgggatac
    10501 aagagttaat ataagtgtat ttgatactcc taaatttgga attgccttta ctgtaaaata
    10561 tattattaga cctccaaata ctcctcctaa taacaactta taattaaaac catttataga
    10621 tactagacac tttaagtcac ctgtaactat tatacttgcc aaaaaaaata ttgctcctac
    10681 agttaagctt ataaaggtgg ccactaatgc tgttgtactt tttcctagct ctccatttat
    10741 aaaagcttca agagctgtag aaccacctgc taataatgca aatattattg cccataattt
    10801 tgtcatggac aaacctcctt ctatataatt ctattaatag aagtttatga tacaacctat
    10861 taattaatta ctaagtatag tttaattttt atacactagg ctttatttgg atatgaattt
    10921 ctgttataat tgttctatcg attttggagg tgattttatg tacacaaatt ttaatatcga
    10981 ttttaataac tttaataaaa aagaaaatgc tattaaattt atgttaatgg gagtattact
    11041 cattatatta ggattattat gccttacatt taagacatta ggtataaaat taatttcttg
    11101 gacttttggt attgcacttt tattctttgc atatttaaat ttaaaaaata ttaatgaatt
    11161 aaaaagatat gctactaaag aagaaattaa accctctatt aatatccaat gggttctaat
    11221 aattgcatgt atattacttt ttgtatttcc gcaaaaaata caaagcatat tttcattatt
    11281 tttaggattt tatttaatct ttaatcaact agtagcactt gtaaatagta agaataatcc
    11341 ttattctaaa tttacaactt ggaatatagt taagattcta tttggtatat gccttatatt
    11401 atctccactt tttttatcta gatttatagt atcaataatg tcttttttca taatattatt
    11461 tggactagtt ctatttttct ctggaaatac agcgagaaaa tattaattat tttctcgctg
    11521 tatttttata ttacttaaaa tagaatttgt ttaagttatc tatttgtggt aatatgtttt
    11581 ttgtacaagc tcagcgtaca attttattag aaataggtga ttttttggat aaatttaaat
    11641 atgcttttga taataaaaga tatcatactt ggaattacta tcttagaaat acttttggag
    11701 aaaaagtttt taaggtatct ataaatgcag gatttacttg cccaaacatt gatggaagtc
    11761 ttggttatgg cggatgtact tattgtagca aagaaggctc aggtgatttt gctggaaacc
    11821 ctaaagataa tcttatcagt caattttata atataaaaga aataatgtta aaaaaatggc
    11881 ctcatgcaaa gtatattggc tactttcaag cctatacaaa tacgtatgct cctcttgaag
    11941 ttttaaaaga aaaatatgag actatattag aacttgaaga tgtcataggt ctttcaatat
    12001 ccacaagacc tgactgtttg ccagatgatg ttgtagaata cttgtctgaa ctaaataaaa
    12061 gaaccaattt atgggttgaa cttggacttc aaacaattca tgattctaca tctaaaatta
    12121 taaatagagg tcatgattat aaaacatttg ttgaaggtgt tgaaaaatta aagtctaaaa
    12181 atataaaggt tgtcgtacac attataaatg gtcttcctgg tgaagattat aatatgatga
    12241 tggaaacagc aaaggcagtt ggtaaaatgg gtgtagacgg tataaaaatc catctattgc
    12301 atgttataaa agatactcct atggaaaaga tgttacaaaa tggtatgtta actcttatgg
    12361 aacaagatga atatatcaat cttgtctgtg accaattaga aatacttcct gaaactatga
    12421 taatccatag actcactggt gatggtaaga gggatgaact agtaggtcct atatggagcc
    12481 taaaaaaatg ggaaatttta aatcaaattg atgatacttt aaaggctaga aattcttatc
    12541 agggctgtaa gtttgtttaa tacaaaataa taactataga aatggttata taaatatagt
    12601 cctttctata gttatttagt atttacaaaa caaaatatta atttgtacat ttatacaata
    12661 tataataaaa aatagatagt ctaaactgta tctacttata ttttatttgt actgtccact
    12721 ttattctata aaatttataa atagttattt tttaatacca aatataattt ggtataattt
    12781 ttgttggact ctaaaatgta taccaataaa tcctttttaa gtatataatt ctaaatactt
    12841 tcagtttttt caatctgctt taacttgttg gacttacaaa atattcttat ttcatcataa
    12901 gaaagattaa gtgctactac tgcagatatt aacatcaaca tcactccaaa taacttccct
    12961 aaggaaaaac tttctcctaa tatagtgcaa ccaattatta ctgaaccaac taattctact
    13021 gatgccacaa cacctgcaac tgacaactct acacctttag atatacctgc tgcataaaaa
    13081 atatatgcaa gtgcagctgg aacaatgcct aacattagca tacaagataa aacatctaaa
    13141 tccttagcat aatttaagat ttcccaaggt cttgaagaag gaatcataaa tatagctcca
    13201 aataagaaac tgtatactaa tattgttgaa cttgaaaatt cctttaaagc atttttacta
    13261 atagttggca taagtgcata tgctattgct gataatactc caagtaaaag cccaaaagcg
    13321 tttaaacctt gaaaatccaa acgtccacca gtcactgcca taattgcacc aataaaacaa
    13381 agaataagtg aaaataattt gcttctagta atattttctt tataacataa ttttgaaaat
    13441 attgctaaaa acagtggtga tgtatatagt aaaactgctg caattgatac acccgcaatg
    13501 tcaattgctt taaaataaca taaattaaac attgcctgac atataattcc tattattact
    13561 gaatatataa ttcctttttt gtttatcttt aagatttgtg gtgtccttat agatgaatat
    13621 acgcctaaaa ctataaatcc aaaaaacaat cttgtaaatg ctacttgttc tgatgtcagt
    13681 ccatttccca ttaaaaactt tccaaataat ccaagtgtag cccataataa ccctgctatt
    13741 gctataaata catacccttt acttttttct cccattttaa attcccttct atttttattt
    13801 agtcaattta cactcttctt tttaagcaaa aactatgcca tcttaaatca atatatatcg
    13861 actctaaaac cctagtcttt ccaataatac taataaattt tcaatttttt tatatttatt
    13921 tttcgcttac tttaagttga tttagactta ttttaattgt aaaatgagtt atatataact
    13981 tatttaaagt taaaatagac tgaaacttat atataaatat caaattttaa gtatattaat
    14041 caattaaacc tattttaata tatcattaaa aatttaggag gaaaatataa aaatgaattt
    14101 agatttggaa ttttatcaaa aaatattaga agcttcccat gatgaaatat gtgtttctga
    14161 tgataaagga ataataatat attgtaataa agcatttgaa gaaaattatg gtctaaaaaa
    14221 agaagatatt ttgggaaaaa atgtttcttt tttagaagac tctggatatt caacaaaaag
    14281 ccccatacca attgtattaa aaacaaagac taaattttca ctggaacaag atactcaaac
    14341 agggaaaaag cttatcataa ctgctacccc tatatttgat gaaaatggac acttagaatt
    14401 tactgttgaa aattgtagag atataactga acttaataat ataaaaaata aacttgaaga
    14461 cacaaaaaag caagtaaaaa aatataaatc tgaagtagaa acactataca gaactgcact
    14521 tagaattgaa gatactgtaa ttatggacgg aatagttatg agaccaatca taaacacagt
    14581 aaatcatgtt tctaaaacgg atgtaagtgt acttttattg ggtgaatctg gaacaggaaa
    14641 aagctcactt gctagatata tacaccacaa cagcaataga tctaatggcc catttataac
    14701 aataaattgt gcaactatat ctccacaact tcttgaatct gaactttttg gatatacttc
    14761 aggtgctttt acaggtgcaa gtactaaagg taaagttggg ctcgtagaat tagctaatgg
    14821 aggaactctt tttttagatg aaataggaga tataccacaa aatctacagg caaaattttt
    14881 gcaattaata caggatagaa cttttactcc agttgggagc ttaaaaaata aaaaggtcga
    14941 tataagaatt atatctgcta caaatgttga tttagtttca aaagtaaaag aaaaaaagtt
    15001 tagagaagat ttatactata gattaaatgt tatagaaata aaattgcctc ctcttagaga
    15061 aagaagggat aatctagtgg aaattataaa atattatttt aataggtact caagtgactt
    15121 caatctaaat aaaactattt ctaaagaagc tatggatgct attgcaaatt atagattccc
    15181 aggcaatata agagaattac aaaatataat tcaaaaaatc ttgcttactt gtacagataa
    15241 tcatataaca atagatgact taccaaacat tcttacaaaa aatatacata ttaccaataa
    15301 tggaaataaa acacatatat cccaaattaa taaggttatt atatctgact caaaatctac
    15361 taattataaa aataaaaatt ttgacacttt aattaaagag tatgaaaaaa atataatttt
    15421 ggatgcttat gaaaaatttg gtagttctta taaagtagcc aaacaccttg aaatctcaca
    15481 gtctaaagcc aataggttaa ttagaaagta tactaatact taattttaaa tttgataaat
    15541 aaaaacttaa cactatttac atattgtaaa tttggccatt tactgttatt atgaatatgg
    15601 ttgaaattat ttaaataaat actgttgact tagtttcata tatttaccat taaactttta
    15661 tcataaatat catatcataa taatatattt aataagtcta ataaactata cgaggtgtaa
    15721 atatgttaat gaatacccat tttattatgg caaaatcaat acttgataat atagatgaaa
    15781 ataaaacatt ctttataagc gaaaaaaatt ttatatatgg caatataaag cctgatgctt
    15841 tttctaaata taaattaaaa aaacattatt tagatgagtc atttaatatg attgtttcta
    15901 aaataaacta tctatgcagt cttaatatag atagtctttc taaatacttt tcagtaagta
    15961 gacttagtca ggaactagga gtcatatgtc attttttatg tgattttttc tgtgtagctc
    16021 acagtgaacg ttgggagttt aagcatagct taaataaaca tgttacttat gaaagagaac
    16081 ttggagcatt tgcaaaagat gttgatttat ctaaaattaa atgtggtact ataaatagta
    16141 gttttgagaa gttttttact aaactttata gtgattacaa aaagaaaact gattatatga
    16201 atgatttaaa attttcagct tatacttgta atagtgtcat aaattatata cttgactcta
    16261 ttttatctaa tacaataaaa tcatatcata tagcaaattg cggttaactt aagaattttt
    16321 aaacttatat aaacttataa ttgaatataa ttaaaatgac tgctctatag aatataattt
    16381 tatacttctc taggacagtc attttttata ctaactattt atctccatta taacatctat
    16441 ggcacttttt acactatcta ctacataatt tgcactttgc tttacatctt cccttgcctt
    16501 agacattgca aaactatatt taaatccttc taacatgcaa atatcatttg gagaatcccc
    16561 aatagtagca acttcatctg gacttacatt taacgttttt attacatgct ctatacttcc
    16621 tctttttgac acacttttag gaactatatt taaagtatat gttccagaaa aatatatttc
    16681 taagacttca ctaaactcac tttttagata aagttctatt ctggataact cttccaaatt
    16741 ttcagaacat acgcctatat ttcctataag attatcaaaa ctacttcttt tttcaaaatc
    16801 tgggtcaact ataaagtcac tagaataatg tctaaaagca gtggtatcac tacccacaat
    16861 tacatcaccc ttatatttaa aataaagttg tgcatcactt gactcaaatc tatcaatgac
    16921 tttttttact aaattatcgt ctatcgttct tttaaaaatt acattataat ctttatcata
    16981 tataaatgaa ccattttcac atacataata tccattcata tctaaactat ctttgataat
    17041 attatgtgct tgtttaaaaa ttctacctgt agcaacatta aactgtactc cctttttttc
    17101 tatttcttca attgctacta tatcttcttt tgttatggtt ccattttcat atagagttcc
    17161 atctaaatca caaaatatat gttttatcat aaattaaaag cctccaaaac aattttatat
    17221 tttactaata ctttaatcaa aataacttaa agcttttcta attgtattct caattcatta
    17281 agtaaatctc tagtagctct taatcttatc tttcttctat ccccattaaa tatatttttc
    17341 tttactattg tttttccatt tatatatatt gcagtataaa ccagtcccac aggcttctct
    17401 ttggttcctc caccaggtcc agctactcca gttgtagata tacctatatt agctttaagt
    17461 cctttagcaa cgccctcagc catttctaca gctgtttgct cacttactgc tccaaactct
    17521 tccaaagttt ctctttttac tcctaatctt ttcattttag aatcattaga atatgttaca
    17581 caaccttcaa gaaatacaga ggatatacct ggatagttta taagagatga agaaaccaaa
    17641 cctccagtac aagattcagc cactgctatt gttagatttt tttctacaag tagcttagaa
    17701 acagcatctt ctaaagcagt ctccccttca gatatggaaa tatcgccttc agtatataca
    17761 tatttaccaa ctctactttt tattttttct tctactggtt ttattaattt aaaagcttct
    17821 ctttcatttt cagcctttgc agttattctt attgtaactt ctaattcttt tgcatataaa
    17881 gcaactgttg gattagtctg ctcattaatt atatcgagaa tttctaattc tagatttgac
    17941 tcacctattc catataatct taaagtctta gatactagca tttcatttgt gaattgttgt
    18001 aagtaaggtt tgacactctc attaaacata gctttcattt ctcttggagg tccaggcaat
    18061 actattataa atttaccatc tttttttaaa attgcccctg gagctgtacc attattattt
    18121 tttagtacta tagcatcttt tggaaagtac acttgtttca tattattttc ggccattttt
    18181 ttccctgttt taacaaagaa agattccaaa acctctagtg aaggtttatg tagttctaat
    18241 ttctgaccaa agtattctgc agcagtttct tttgtcatat catcaccagt tggcccaaga
    18301 ccacctgtag taattacaaa atcacttctc tttaagcttt catcaaaaca ttctaaaagt
    18361 ctttgtttgt tatctccaac agtactctga tggtatactt ctattcccaa tgatgcaagt
    18421 tctttagcta aaaattgaga atttgtattt actatatctc ccaataatat ttctgttcct
    18481 acacttatta tttcagcttt caaaatttat cactccttga tttatagcca ttaagactag
    18541 tcttaagttc ataacaataa ttttagcaaa aataataaca taaataaagt taaaaaatca
    18601 tttaaacata tctttaaact agattattat tctaaaacca cacataatat aaacttcgta
    18661 tatagtggta ctttcatcct caactgttaa ttcatataat taagtatgta aataaaaagt
    18721 ttactttaaa ataataaaaa ttaaaatagg agtgtataat atgaaaatag cagttataat
    18781 gggtggaata tcatcagaga gagaagtttc tttaaattca ggaaaagaga tatataataa
    18841 ccttgataaa aataaatatg aagttgtaaa agtaataata gatgataaaa aagatatatt
    18901 tacaaagata ccagaagata tagattttgc aatacttgct ttacatggaa aatttggtga
    18961 agatggatgt atacaatcaa tacttgagac tatggatata ccatactctg gatgtggacc
    19021 tctttgcagt gggatgtgta tggataaaaa tataactaaa aaaatgctta gagattcaaa
    19081 cctacctact gctccatggg ttttagtaaa atcagttgat gaaatagact atgatgaaat
    19141 agataatata ggttatccag tatttataaa accaaactca ggaggttcaa gtgtagccac
    19201 attctttatt cattctaagg atgaagttga aaaagcagtt agaaaaggtc tggaagttga
    19261 tgaatttgta atgattgaaa aatatatacc aggtggagaa tatacttcat tcatattaaa
    19321 tggagaagtg ttccctacaa tatctataaa atctgattca ggattctttg attatgaagc
    19381 taaatactca gttgaaaaag gtgcaaagga agaagttgtt tacttagatg aagaacttca
    19441 aaaaagagta aacgaaattt ctgagacttg ttggaaaatt tttaattgca aagcatatgt
    19501 aagagttgat atgattataa gtgaaggtat tccatatgtt cttgaactaa atactcttcc
    19561 tggaatgact caaactagtt taattcctag aagtgctgct gctagaggta ttaagtacag
    19621 tgaactatta gataaactta tagaatactc tttaaattag atgaaataat ttgaggtggt
    19681 aatttgatat tttcaaatct aaaattaaat gataatgaac caatttatat acaacttaaa
    19741 aattatataa gtgatatgat atcaaaagga ctaattccag acaatagtaa gctcccttct
    19801 acaagggagc ttagtcagct tttacaagtt agccgaaatt ctgtagtttt aacttatgaa
    19861 gaattaaaat cagaaggatt aatctactcc atttcaggaa aaggtacatt tgttaaatca
    19921 aagaataaat cttcaaatac tacatggtca ttaaactggg attgtttaga gaatacatat
    19981 tctaaaaaag ccaatgaatt ggacattata aaaagtgaaa ttccttggag ctctgacctg
    20041 atttccttta aaagtatttc tccagatgga gatttattcg acatggaaga attaaaaaaa
    20101 tcctttttaa atagaatttc actagaagga cataaattac tcaactatgg atatgcacaa
    20161 ggttataagc cccttattga ctatttacta gaatatatga caaacaaggg tgctgatata
    20221 agtaataaag atatactaat aacaaatgga ttcacagaag gctttgatat tattatgtca
    20281 tcttttaccc aagaaaaaga ctacataata tgtgaaaatc ctactcataa tactgctata
    20341 aaaattatga aatctcataa cctcaatatc ttaggtgtag atataaatga agatggtttg
    20401 gacttcaata tgctagaaga caatttagtt aagtataaaa ataaaataaa gtttgcatac
    20461 attacaccct cttatcacaa tcctacagga attgtaatga ctcctgaaaa taggtacaaa
    20521 ttctataatc ttatgaaaaa atacaatata gcaattatag aagatggatt taatgaagaa
    20581 ttactctaca atagttctca tatatttcct atctgttccc tagataatat gaataatggg
    20641 gtcgtatata ttggtagttt ttcaaaaatt ttatttcctg gaatgagaat tggatggata
    20701 tttgcagata aaaaagtaat caataaacta gaaagtgtaa aaaggtgcag aaacatacat
    20761 gtatcctttt tagaccaagg aattttattt gattatttaa gtaatggagg ttttgaaaaa
    20821 tacattaaaa aaatacgtaa attctatgga gacaaattta actttgcata taagtgtata
    20881 aaaaaatata taaaaacaga atatatcttg ggtgatggtg gtttgcatat atttataaaa
    20941 ctaaaaaata tagatactag agttttatta gaaaaatgtt atgaaaaaaa tgttatattt
    21001 atgcctggag atttattttt tacagataac tctggttttg atactttaag actcggattt
    21061 tctaggttat cttttgaaga cattgaaatt ggaataaaaa taattggaga aactataaat
    21121 gaaatgttct aggttaacta aatattgtta gcctagttta tttttatgag gtataatata
    21181 tatagtttat atgaatctaa tactggggga taatatgagt aaaaagtcaa aacgaagaaa
    21241 aattaataaa ttaaaattaa cgattgtaat aactgtatta tttcttgctt tattatctat
    21301 atatgagatg ctgttctcta atcccaacaa aaaaggtaat ataaagagtc aagaaactat
    21361 gcaaaataaa aataatacaa cagatgattc taaaaataat caaagctcta ccaaaaagca
    21421 ggaagataat aatatcaaac ctactttttc atattcttca ataccagata atataaaaaa
    21481 taaaatgatt ggtaaatcta tgcctactga tgaacctata agctttgata gtctatctta
    21541 tttaaaactt acatattatg gatttgatga aaaaactcat caaggagaaa tgatagtaaa
    21601 cagtgaacta gctccagaag tagtggatat ttttaaggaa ttatacgaaa aaaaatatcc
    21661 aattgaaaaa attaagttaa tagatgacta tgatgctgta gatgaaaaat ctatgtctga
    21721 taataatacc tcatcatttt gttatagaac tatagctggt acaaatgtag tttcaaatca
    21781 tggtaaagga cgtgctatag atataaaccc attacagaat cctcaagttt ctggaaatga
    21841 tgttacacct aaagtaagta aagtttatgc tgataggtct agcacaaaat ttggaatgat
    21901 aaaaaaaggt gatgattgtt ataatgcttt tgtaagcaga ggttggagtt ggggtggcta
    21961 ttggaaaaac ccagattatc aacattttga aaaataatag attagaaata aaggtgaatt
    22021 atatgaattt aatgacattg gaaaatataa gtaaaagcta ttctgaaaaa aaattactag
    22081 aaaatatatc tcttggaata aatgaagggg aaaaaatagg acttattggt gtaaatggta
    22141 ctggtaaatc taccttactc aaaattattg caggagttga agaaagtgag actggtaata
    22201 taacaaaaac taatggtatt aggatagaat atctacctca aaatccaact tacaatgaaa
    22261 attcaactgt acttgaacaa gtatttaatg gaacttctga agaattaaag ctacttggtg
    22321 aatatcaaga aatcctagaa aaacttaatt caaactttac agaggaatta aataaaaaat
    22381 tattatcagt acacgaaaaa atagatgcct taaatctttg ggatttagaa agtgaagcta
    22441 agtcagtact tacaaagctt ggtataaatg actttaatca aaaaatagca gaactttctg
    22501 gtgggcaaag aaagagagtc tctctggcat cagcccttat tacaccttgt gagtttttga
    22561 tactagatga gcctacaaac catctagaca atgatactat agattggctt gaggaatatc
    22621 ttaattccag aaaaggttca ttgcttatga taactcatga tagatacttt ttagaccgtg
    22681 ttacaaatag aattattgaa ctggacaagg gtagattatt cagttatgat gggaattatt
    22741 caatattttt ggaaaagaaa atggaaagac tttcgctaga agcaagtatt gaagataaaa
    22801 gacaaaattt aataagaaca gagcttgcgt gggtaagacg aggagctcag gctcgtagca
    22861 ctaaacaaaa agctcgttta caaagatttg atgaacttat aaatagagat tcttttaaac
    22921 ctgatgaaaa tctcgatata tctgttgcat caagtagact tggaaataaa ataatagaaa
    22981 tacacaatat atctaaatca tttgaagaaa atactgttat agataattta gaatacactt
    23041 taactcgtac agatagaatt ggtataatag gcaaaaatgg tatgggtaaa tctaccctta
    23101 taaatatact taatggagaa atagagcctg atagtggata tatttcaatt ggagaaacgg
    23161 ttaaaatagg ttgtttttct caagacgact ctcatatgaa tattgatatg agggctatag
    23221 actatgtaaa agaagctagt gactatatag aaacttcaga tggtactagg attacagctt
    23281 ctcaaatgtg tgaaagattc ctttttaatg gtactatgca atatactttg ataggtaaat
    23341 tatctggtgg tgaaagaaga agactacatc ttcttaaaat ccttatgaca gctcctaatg
    23401 tgcttctttt agatgaacct acaaatgatt tagatattga aacgcttaaa atattagaag
    23461 aatacctaga cgaatttaaa ggtgtagtag ttacagtatc acatgataga tatttcttag
    23521 atagaatttg taataaaata tttgcatatg aaggtaatgg aaaaattcat atctatacag
    23581 gtaattacag tgattatctt atttatagag agattcaagg aattgaattt gaagaatcta
    23641 aaaaggaatc agttaaaaaa gatgactcta ctaccctaaa aaaagaaaaa cctaaaaatg
    23701 ataaaaagct taagttctca tataatgaac aaagggagtt tgaaaatatt gactctgata
    23761 tagaaaaact cgaatctaaa attgcaacac ttgatgaaag tactgcaaaa ttttcaactg
    23821 attttactaa acttcaagaa attttagatg agaaatctaa actagaaaaa gaacttgaat
    23881 acaaatatga aagatgggaa tatttaaata atctagctga tgaaatagct aataataagt
    23941 gatattaaaa taatcttaag tttaataagt tttgctttaa atctgtactt tataaacatt
    24001 ttaaaggaag tgtctcaaaa tgaacttttt agttttatga gacgctcttt tttatgagaa
    24061 atcaaatatg ttttcatcat ttcaacaata caaaagaggc ttatctctat tttgagacag
    24121 cctctttcat aattaccttc taatttatat gctctaatat atctataata attcttatta
    24181 tatctatata tccagtcttt caatatagtg acaattaact tcaatatgat ttaaaaatac
    24241 taacaacctt tcataaagtg gatgagattc ttctccatat ttagcttcta ggttcttgcc
    24301 tatttctcta acagtccttt gaccatcaat ttgtaaaaaa acaaaactgg aatattcatc
    24361 tagttctatt tttttgtatt taggtattct agcttttaac tttctaaaaa acttttgaat
    24421 tttatggtcc tgtttttcaa gtatagtaac aacactattt tcagctactt catattcaag
    24481 tccatcagta attttaaata caatatctaa aacatcatta ctcttgctca ttatttttta
    24541 ctttagataa aacaataggt aatgctgtaa gcacaactaa aactactaat aaagcaattg
    24601 ccattgaatt tgttgcagca aatccacttg gtacctttgg agttacaact ccagttactt
    24661 gtaatattat acctattaaa ccaatgatag aaccaccagc aacaagacca gaagataaac
    24721 ttataccatt agaaacttta acttcttttt ctttttcagt tttagatact aattcaacaa
    24781 ataaacgaat taatgctcca actaatatta tagaagttgt tgcaattggt aaatagaatc
    24841 ctatagctat agtcattatt ggtaaattta atgcatatag aactattgcc ataaatactc
    24901 caacaataat cataacccaa ggtaaactac ctgacataat accagaagtt aatgttgaca
    24961 ttaagtttgc ttgtggtaat gcaaattgta cattatcacc agttgctcta agttggtcag
    25021 aaagtaataa aattactcct acaacaacta taacaccaac tatacttgca attgtaaagt
    25081 aacgttgcat ttcgtttttg ctaccaccaa taatataagt tactttttga gattgagtat
    25141 aacctccagc tatagcaata gcaacaacta taaatgaacc aaataaaagt aatgatttat
    25201 tagcttctaa atcagtccat cccattataa caaacactaa tgttacaata actagagaag
    25261 ctatagtcat accagaaact ggaagatttg atgttccgat tgttcctgtt aaacgaccag
    25321 ctactatgac aaataataaa gataataaaa gagatatgat agctccaata attgccataa
    25381 caatgttacc agaaattaag aatgctgcta aaaatccaat aactactcca cctaataaaa
    25441 gtatcatttg tatagatgaa ccttcttctc cctctccagc acttgattta gctttaagtg
    25501 tttcttttat agaagcgatt atagttggta taagttttat tgcaccaata atacctccac
    25561 aaagcatcat accagcacct atatatttta cataactact agatattgct ccaacatcca
    25621 tttggttaag aggcattgca ggattattcc ataccatagc tccatcttta gccatatctg
    25681 taaagtatcc tattaaaggt gctataccaa agtttgataa aatacttcct gcaaacattg
    25741 ttaaagaaac ttcaagccct actataaatc caattcctaa aagtagagga tttacttcaa
    25801 tatcaaattt ccatttgtag aatttgcttc ctacaagact cattacattg tttgctacat
    25861 ttaagaatga accagttaat acagtaataa atccacttat tacaaatcca attcccatgt
    25921 acttaattga atctccacca gcctctgaag caacaagtgt ctcagatata gccattgatt
    25981 ctgggtacat aagtttacca tgttcttcaa ctattagata gttgtgaact atagcagcaa
    26041 ttcctatacc aaataaaact ccaccaactc caacagctaa gccttcaaag aatgtaattt
    26101 ggcttccaat taatataact gctggtaata cgaaaataaa tccacttgca acagattctc
    26161 caccacttga cataccttgg attaagtttt taccaagaat accctttgaa cgagcaaatg
    26221 ctccaacaaa agcagaacct attatagctc ctggaatacc tgcggcaact gtaagaccgg
    26281 ctttcattcc agagtaagtt gtagatgcgg caaaaatggc agctaaaata ataccgataa
    26341 tcagtacagc tacatttcca ccggttctgg acttatctgt gatatatgga acgtaatctt
    26401 ttccactaac ctcaccataa gcacccttag gtaatttttt gttcataaaa ttttcacccc
    26461 ttttcaattt gtatatatta taacatatat acatataaaa cttaactttt tattatttta
    26521 caaatagcga gtcaaaacta ctaaaattta accctatatt attaatttct acttttagat
    26581 atttttatgc taattttctt tttatttttc aattctacta aaaactatta agatataaaa
    26641 taaaaaaatt ttttaatgta aaattaattt tgtaaaaaaa atgctttaaa acacggaaaa
    26701 gtataaaaaa tacaataatc attcttataa ataaattttc accatagtaa atatatacag
    26761 aaaattcttg tttttatgca aattgattct tttataaaaa taagtgtcat aaagaaatgt
    26821 ctgaaatcac tttatgacac ctatcataat aaaaaattat tctggtaatg ctcttttatt
    26881 tacttttccg attggtgtaa ctggtatctt atctatcctc attattattg ttggaatcat
    26941 atatggaggt agatgctcat ttaaatattc tctaatagtt ctttcattta tcttaccact
    27001 atcttcctca tcaattacat aatatgcaca tatatacata tctccatcat catttgttct
    27061 cgatatacaa acaacacttt taatttctgt aatattattt attatatttt caatctcata
    27121 tagctctatc ctaaactcat caatttttac ttgattgtcc atccttccaa tataatctaa
    27181 atttccatca tctaaccatc ttactaaatc accagttcta tacattaact tattatgttc
    27241 acaagttttg taaggattct ctacaaatac ttgctctgtt agcccttttt tatttaaata
    27301 tcctcttgat atttgaatgc ctgatagaca tagctctcct ggtgctccaa ttggacatag
    27361 tttgttcttt ttatctaata catatgcata agtattaaat ataggttttc ctattggtat
    27421 ttttccatat tctctgtcca catgaaaaga agtcgataca acagtaaatt cggttggtcc
    27481 atactcatta tatagttcat aattacgctt tctatatcct tttaatcttt ctcctccggt
    27541 ctgtacaact ctaagtgaat tattattgca attttgtata aataaccttg caaatgctgt
    27601 tggcaatgct agtatagtta tgtcattttc ctcacagtat tcatttactg tatattcatc
    27661 aaatttagct tcttcaggca taatatctat tgatgcacct acaagcaaat aagggaatag
    27721 ttgtttcatt acagcatcaa aactgaaact taagtatata ccacatatat cattttctgt
    27781 agcgcttata gattttacgc tataataaca catatttact aaactcttat gttctatagc
    27841 tatggtcttt ggcctaccag ttgaccctga agtagatatc gtatatgcac aatttgatga
    27901 tgttattttt tcagttaatt catatccaag cttaaacatt tcttcatcat ttatatcgag
    27961 tactatggta ttctcattta caaccttact tttgagttca tctgtagtta tcactacttt
    28021 tgcattacta tcttcaagaa ggtaattcaa tctttcttct ggattacttg tgtctattgg
    28081 aaaaaatgct ccccctgatt tcataatccc tattgctgta ataattatgt taatatctct
    28141 tggtaacatt acagctacta tgtcttcact ttccactcct atatgattta aataacctgc
    28201 aagtttatca gttacttcat ccaattcttt atatgttaac tttctatttt catccctagc
    28261 agctatatta ctaggtgtta ccttaacttg ctccctaaat aaatcaacat aacttttatc
    28321 atagggtatt tcatattgat tgttattaaa gtcttccaat aatacttttt cttcttcctt
    28381 acatacaaat tctaaatctt ctattaaaat atcattatct tctattattt gctctattat
    28441 ataatcaaat tgatttaaaa ttcttctaat agtttctctt ttatatatag atggtttata
    28501 ctttattttt attttaagtg ccctcttagt atatactatt acagataaat catatccttt
    28561 tttttctatg tcataatcat atgataaatc aaaactttta gctataaata ttgtgtttat
    28621 aagcttagta tttagatgat ttttattctc tatatctgat aacaaatagt atccatactc
    28681 taaagacctg ctccactgcc tttttagctt ccttacaaca tctataaatt tttcactttg
    28741 tctaactctt actcttattg gaattatatt cattgtttta ccaaaaacta catcatcttc
    28801 atatatatac ttttgaagta taaggccata tatagtttct atgatagagt ctatgctaat
    28861 attgttcact ttagaatatt gaattaacct ttcatgtttc tcaatattca tcttaaaaac
    28921 ctcatctact acttcatcag aacaatcttt ataaaaaaaa tcatttggaa tttttgctat
    28981 attcgtataa tcatctaaca aatccatcca ataattcata gctcgttcta aattaacttc
    29041 atacatatca aaattccccc ttactactaa gtctatagaa aaaattcttt tggaatttta
    29101 ttttcacaat atataaatat atgaataata catatgcaag ctctaaaaac atgagcttgc
    29161 ataaaattac acttattatg actactaaat tc
//
LOCUS       DAFAZV010000053        28669 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFAZV010000053 DAFAZV010000000
VERSION     DAFAZV010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28669
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.053"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(258..920)
                     /locus_tag="KOU88_003197"
                     /pseudo
     CDS             complement(258..920)
                     /locus_tag="KOU88_003197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016440163.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
     gene            complement(1080..1616)
                     /locus_tag="KOU88_003198"
     CDS             complement(1080..1616)
                     /locus_tag="KOU88_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBK3213052.1"
                     /translation="MIGLKCGMVKLLEHQMIWDKSAKDVIILLKSIWDKTAIDIQHIG
                     STSIPSIRAKPIIDIVVGVASLEEAKLYLERLEQCGIVFRGQDVPKQLLFAMGDFEKN
                     TRTHHIHVVEWNSVAWNNYINFRDYLNTFTDKAKLYDSHKQKLALQFEDNRKIYTQRK
                     QELINILLEEARLWRINT"
     gene            complement(1689..2102)
                     /locus_tag="KOU88_003199"
     CDS             complement(1689..2102)
                     /locus_tag="KOU88_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003507530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBK3213053.1"
                     /translation="MKMPKESIDTIMFAPCGMNCMVCYKHCYHKKPCAGCLNGDTGKP
                     EHCRKCKIKDCVCQKGLFYCFECFNFPCKLIKNLEKSYNKRYQASLMENSKFVQQYGL
                     EKFMQKQKERYTCSKCGGIISIHDRECSECQEKVK"
     gene            2568..3122
                     /locus_tag="KOU88_003200"
     CDS             2568..3122
                     /locus_tag="KOU88_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid stabilization protein"
                     /protein_id="HBK3213054.1"
                     /translation="MDEKILELLQEMQGNISNMQGSISGIEGTISDMQSNINGIEDTI
                     SGMQGTISDMQGSISGIDDTISDMQGSISSMNGTISDMQDSITDMQVEIKEVNSRLDN
                     MEPDIKDLKTGQVETSSRLDTIQSDVTEIKSDVKINRNTLDTVIKHTSSLVKDTSDIK
                     NDLNNIEIVTSKNSNDIAKLKSVK"
     gene            complement(3730..3909)
                     /locus_tag="KOU88_003201"
     CDS             complement(3730..3909)
                     /locus_tag="KOU88_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK3213055.1"
                     /translation="MLQTGKQGADKKYLDNMFFVKGYVEELLFLDNSYDIVFSCIVFH
                     HCTNVQNIFCIFWKW"
     gene            complement(4135..4668)
                     /locus_tag="KOU88_003202"
     CDS             complement(4135..4668)
                     /locus_tag="KOU88_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBK3213056.1"
                     /translation="MQYISYYHSPIGNILLASDNIGLTGLWFENQKYYAYNLDQEHQE
                     KELPIFEQTKKWLDIYFSGKEPNFTPSLHMVGTPFQTTVWKILQQIPYGKTITYGEIA
                     YKVAQQKGISKMSAQAIGGAVGHNGISIIIPCHRVVGTNGSLTGYAGGIDRKIKLLSL
                     EKVSVQHYFIPKKGSAL"
     gene            complement(6416..6988)
                     /locus_tag="KOU88_003203"
     CDS             complement(6416..6988)
                     /locus_tag="KOU88_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBK3213057.1"
                     /translation="MWIYQKTLEHPVNIRQADPRMAKYIMTQLGGPNGELAAATRYLQ
                     QRYTMPTGKSRALLTDIGTEEMAHVEIISSVLYQLIGNCTPEELKAAGLGSNYANFGH
                     GLQPVDSNGVNFTTSYINVFGDSVTDLHEDMAAEQKALATYYQLINLTDDPDLKDILR
                     FLGEREVVHYQRFGEALMDVYEFTECKHQF"
     gene            complement(7050..7313)
                     /locus_tag="KOU88_003204"
     CDS             complement(7050..7313)
                     /locus_tag="KOU88_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein CotJB"
                     /protein_id="HBK3213058.1"
                     /translation="MSLNRRELLERISEYQFACIELNLYLDNNPRDKKALDSYNRYCD
                     KFTQAVCDYESKYGALTNFGYESSEYPWSWISEPWPWDKSFYK"
     gene            complement(7313..7534)
                     /locus_tag="KOU88_003205"
     CDS             complement(7313..7534)
                     /locus_tag="KOU88_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat associated protein CotJA"
                     /protein_id="HBK3213059.1"
                     /translation="MGYLKEDKQDYCCEFARPYINRQIYDDTYNPKTALKRGTLFPEL
                     DLIESNNYNDWLYANPKNRVRAKKGGNMY"
     gene            complement(8050..8586)
                     /locus_tag="KOU88_003206"
     CDS             complement(8050..8586)
                     /locus_tag="KOU88_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBK3213060.1"
                     /translation="MEYKSPVYGIIAVPIEKIESNDYNPNAVAPPEMQLLYKSIKEDG
                     YTMPIVCYYNEEKDKYIIVDGFHRYRVMLENEDIYDRENGLLPVSVIDKSLDERMAST
                     IRHNRARGSHNVDLMSKIITELCEIGKSDEWISKHLGMEVDEILRLKQITGLAYLFKD
                     KEFGNAWIPFDSDIEEEN"
     gene            complement(8604..9917)
                     /locus_tag="KOU88_003207"
     CDS             complement(8604..9917)
                     /locus_tag="KOU88_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3440 domain-containing protein"
                     /protein_id="HBK3213061.1"
                     /translation="MDKRYLESDVFEAFQERLSYLFNEFDYIYVSFSGGKDSGLLLNL
                     VLDYKRKNNISSKIGVFHQDFEAQYSLTTEYVEKVFEDNIEDIEPYWVCLPMATRTAV
                     GNYEMYWYPWDDEKEELWVREMPVKEYIINQKNNPFTYYKYKMRQESLAKQFGRWIRD
                     IHEGAKVVCLLGTRAAESLQRYCSIVNKQHGYKGKCWITKEFKNVWTASPIYDWEIED
                     IWLAHYKFDYDYNKIYDLFYKAGVAPRKMRVASPFNDSAKESLNLYRILDPDVWVKLV
                     ARVQGVNFTSIYGKTKAMGYRSVKLPYGHTWKSFTYFLLDTLPENIRNSYIKKFSTSI
                     EFWQNTGGGLSEIVIRELLRKGYKIELNGVSNHTKDKKSRVIFLDDIPDDTDDIKFTK
                     DIPSWKRMCYCILKNDHMCRFMGFGPTKEQRIRTEYIKKKYEKIH"
     gene            10272..10712
                     /locus_tag="KOU88_003208"
     CDS             10272..10712
                     /locus_tag="KOU88_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3788 domain-containing protein"
                     /protein_id="HBK3213062.1"
                     /translation="MYERMLDKSNKPCLSQIIEYIGKDGYARLCKLETYLKTQYNLSR
                     ELRFPFGNNYGWGYKYSHKSFHLFYAFFEKGAFTVLIQIGDKQVPAVEKTLVALTPKA
                     KELWVTRYPCGNNGGWIKYRILEDADLLDIIQYIRAKKSPPKQN"
     gene            complement(10897..11085)
                     /locus_tag="KOU88_003209"
     CDS             complement(10897..11085)
                     /locus_tag="KOU88_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK3213063.1"
                     /translation="MNKNNNLVIICMFIGMILGMAIGCAIGISKGNVGITMCYGLIFG
                     MIIGICIGTIIKNSNKKE"
     gene            12118..12513
                     /locus_tag="KOU88_003210"
     CDS             12118..12513
                     /locus_tag="KOU88_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213064.1"
                     /translation="MNILKMKKTGIFLGGVLFGTVGVKILSSDCVKKTCTRATAGALK
                     VKDSVLETTTKIQENVEDILAEAKEINEQEDLSTSKVNVVQDTLKCEQEVLKTETIKT
                     VEDTNSNSIKCEEIKDNVIEEKNNTCTTE"
     gene            12556..14655
                     /locus_tag="KOU88_003211"
     CDS             12556..14655
                     /locus_tag="KOU88_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBK3213065.1"
                     /translation="MNFYIKHEIRGRIRFDLQLGKLNNKQSDTLLYYLTSINGITKAK
                     VYDRTGDAVIYYTGEREYIIREITKFSFNNSKIENLVPEHTSRELNNYYRDKLANKLL
                     VKSISKIFFPKSLRFFLIGLHSIKYFKKGLSSLLNKKIEVSVLDATAIGISIFRKDIN
                     TAGSVMFLLGIGELLEEWTRKKSIDDLAQSMSLNIEKVWLRKGDTEILIPISEIKEGD
                     LVSVTMGNMIPLDGVIVSGETMVNQASLTGESLAVNKKEGSYIYAGTVIEQGNIVMCV
                     KEKAGTTRFQKIVTMIEESEKLKSSVESKFEHLADTLVPYSFLGSILTYAITRNPIKS
                     LSILMVDFSCALKLSIPISVLSAMRECNNNNITVKGGKFLEGVACADTIVFDKTGTLT
                     KAQPTVSDIITFQNYNKEDMLRLAACLEEHFPHSIANAVVYEAEKQGLSHKEMHTEVE
                     YIIAHGISTKVDDKKVVIGSKHFVFEDEKCTIPDGEEDKYNNLSDEYSHLFMAISGKL
                     SAVICINDPLRKEAKYVISNLRECGIKKIVMMTGDSEKTAKSIASKVGVDEYYSEVLP
                     EDKANFVKSEKLKGRKVIMIGDGINDSPAISESDVGIAMSEGAEIAREISDITISADN
                     LNNLIVLKQISNKLMKRVDLSSKFIIGFNLGLILLGVGGFVRPSTSAFLHNTSTVGIS
                     LNSMTNLLENTNTYNYH"
     gene            complement(14880..20090)
                     /locus_tag="KOU88_003212"
     CDS             complement(14880..20090)
                     /locus_tag="KOU88_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBK3213066.1"
                     /translation="MANKLYSEIVNLLEEGRDELRKYDLKEKSILLFLGASGVGKSTC
                     INYLKGCVMEEKTDEETGQIYITAKDSAVEIGNGVYSKTLCPEVVDIANRDFSLCDCP
                     GFFDNRGAEYMIAGAMLVRETISTSSKVKGMVVILDYQSLLDSRHTLLIETGKNLKDM
                     LGDYAKYKENFFFLINKIPKTLIGNVTEEKIRNILEKAKEDLDSQEKDYDGCKELVYL
                     LNVALSDGVSIKLCNPLDKQPEKLLDEMKNLPETFEKTDLGLMLTASCKIEIQKAVDV
                     TYKDLEKLLVPYIESVKKGMEDSISILSSINSLKDKKIQLDKMYTDLCSRTNNMKELM
                     EFVQELSYGDGVQKVNILEETRLLLELNSYCSETHIVGLSELLKSLLKNTLEDTLKDI
                     KYWIAEEEYREEEAKKLEDAEYRIEKIQSCTYIKSYEKENVLSIYIPIPKVNLSDLTK
                     IISGYQLNILSSIYMYGDCELKIDCNMEKEVFSGKNIVLLTEKLHIPEGTYSINVSGK
                     DAEKLVGESSIYDGMNGRNGNNAGTSGDIILSFKEIEKRGELKLYVDGGRGGNGQDGK
                     KGDTGITGEAGANAKIGSKKESKEFANVKGTKYYVVKAEKGKQGGTGGTGGNGGNAGL
                     GSKSGQVYLLGKAPLLKSAISKKDGNHGLAGKGGSGGAGGAGGLGGIRGIYEETIRYI
                     GTSPPMDNSDRNYYYFDRYVFNHALNQKQAADDGEKLNTLYEEHKDWTISKREDSGSA
                     GAEGKAGHSGDALKEKELLKQEYSLSIDTFFYEFFERFGFSGIKGYRNLRLLCAVGIL
                     EADILEFSHIYEIFYAVEKIEMQLNREILQKYYSFEKKNKAVLSMDDMNIKKEFYKEA
                     KEIYEYLINKLMQSDRIESFVGKNQNFSEWSMILFALEQKTAFYVQMIEESEIGGNRV
                     TDIRSLTDYLDKTLRELEQGKKDELKEGYFNTYKESILTQIESGNQQIEVLKNELENK
                     MLSVNAKMNLLIQEIIKMKEDEQEDIEELKKKQAKLEEQMKTQLILSGIQSALSLLTA
                     FSGVGQACLGAFDSAKSLKENLSAKEEEYQWTNRMVDFSDFKLDSDGMRFVLGEQLSE
                     DRKNALDKMTYNLAGVDEERRTKFDQIKEIIVKSIDDDNYADKADDIQRAKEGLSESE
                     YKEIYTKIQKKEIGMLEANYNNKQQKDKLAALEKSKQAIERQQKTSKIKNALSIGSSA
                     CSLINTAISGVNNCLNVKSSFESKIEVVKEAIKDKENNIKKLDELNTQMVEFKDKTLK
                     ESVIPFVEKFDSTVKNQDIFENEISKLKMKEVLTELSTKFGSLKMENSEEISIIFKKV
                     QDMMETQIIITDKIDKKKDNLAMGELIYQMSDSGNQMNEYQKKLIHQIELNQVRYLCQ
                     VEAAAFQLWTFPFGSNIVNILNRCHVGITEDENEVINQAKEQNRQIREFLDQDAYQWQ
                     KTDNHILKVALTGSLDGKSRVGFENTYSLYDCNEEEVKKLLTGDEISFEVPLNKNFDA
                     IKYVTMYANIPNLRRNILEDSLKVKVHIHLYDSGYFSLYDDKKDVYYQYVFPQNYINI
                     THGLDIKYNDSDSINSIWSSVEDKGIEKFKNAGLNSGRSPYSMAKISLKAHFNKKLSY
                     DSLTNEQKKKLESYFDKPSKYAWSDSIDILRSLGYIDLKGILSKSWYEIKKDIDSDGE
                     IMKHFSILQVDLLERIIYEQTSILKENIPNLTIELVGCGIYVESEFNYLKQNDLKCYE
                     ERLVENTIIG"
     gene            complement(20105..22600)
                     /locus_tag="KOU88_003213"
     CDS             complement(20105..22600)
                     /locus_tag="KOU88_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3213067.1"
                     /translation="MPENNNQLLEEITLLLNEGKVAINKAENQNLILILGGTGCGKST
                     AINYLAGCVMMEVEDEDTGISYIDCLDPVAEIGSGAVSQTLYPNIVNMRKPIEGMDAK
                     LCDTAGFSDNRGVAHDISAAVSLGEVFKNSASICAVIVLIPEADILDSRLTKVLDLFQ
                     QLNMCLHKENFKGSITFFISKSFLGRTEKQIYNVIKRKYEQLCENLDSNIEEKAWLFE
                     ELLKDNGKNIHLCKPLASDEREGLLKQVLELDEVKDKTSAFQYPISADARLVLDTLIK
                     EIQNNIVSSLEDYVKAYTEDFINIIGSITMIQEIAKYDEVVKVFKNWLESTTSLTIER
                     FINVLAKQSGLFLQDSCMKLQNKIKGNLDIIDALSKYTEHGTGEILLPSVHMEFIIEK
                     ASKKIMEQNFIIIRKNLEKVLVSYEVQKQVFTLPNREKLMEVANKKDYVYSVSDFNSI
                     LTNVTVTQNEELEDSITRLSAYGEEGNEIIREFIGKYILNPFIVKTININDKKGIEIR
                     ALIPNLVISSVLEYFKNRKVDDNVSTFMFFAKDTIYMDDNLGMNFASEKNIILASNNL
                     DVGSNVKINVSGKSGELVDNSMYGKNGEDGRDAGNIYLYIKEEIRNYRLTLIANGGNG
                     SKGIDGENGETGASGSNGADAGYTSYFHGQMFKGYFEKGTSGKKGEKGGAGGNAGRGG
                     NAGKKGNIYFISDSEEQKNRIINHCDITVKDGEAGPNGRPGLGGYGGSGGYHGYNTLS
                     FSPSGIDKTVYYTGYFTSWDYKLDSIIKYHIEFSGGSWNEGKTGPAREYAEYGDRGDN
                     GGFNAPNTKLSTAVSKVEENLIKEKYQGYCSEI"
     gene            complement(23237..23524)
                     /locus_tag="KOU88_003214"
     CDS             complement(23237..23524)
                     /locus_tag="KOU88_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213068.1"
                     /translation="MRLNVTKQNTIEVENSRKEDVYFVIVDNVFFERQGDVFNSITNN
                     NLNNYDVKILPTDNIFLELKITSTKDLEPVFIVVEDRQYNHGSIMFKPVLV"
     gene            complement(23544..23819)
                     /locus_tag="KOU88_003215"
     CDS             complement(23544..23819)
                     /locus_tag="KOU88_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213069.1"
                     /translation="MSLFVGGWSKFRAVEEEDLKVFNEAVGMLEGVGYEPLIVSTQVV
                     AGTNFKFICNATSVTNPPQNYLAEIVVFKPLPCDEHNATITSINIIK"
     gene            complement(24454..24633)
                     /locus_tag="KOU88_003216"
     CDS             complement(24454..24633)
                     /locus_tag="KOU88_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213070.1"
                     /translation="MGKDRFEKVYSQGKINATEIWVDKETGVNYVFHYYGNAAGFTPL
                     LDREGKPVISPIVSK"
     gene            complement(24918..26384)
                     /locus_tag="KOU88_003217"
     CDS             complement(24918..26384)
                     /locus_tag="KOU88_003217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3213071.1"
                     /translation="MKRKPQYLVIFEHIIQQIYTGKITIGDRLDSIKSMSEEYMVSKN
                     TIKTVIKMLSEKGFIETKAGSRPVLIQSTSKQSIESDLLYEKILQISEIYKIFSLIFP
                     SIAMYNIKRFTSKDFEELNEIIDCMEKNSSNYLVFKEQRLKYINKLISKTNNFLIHHF
                     CEIIQHDVIISQLAYNFDNLDNCCIDFFRNKYIEQVRKTYLYGLDGNLIEFKKLLTYM
                     YKACRESILKMVENRAPQSIDTSSFNSVTLEKCYLYDLIVSDVICQIFEGNIKIGDCL
                     PSITSIINRYNVSLPTVRSAYNELNELGIAKTINGKGTYITLFSEYDDDYINTEEGAK
                     RLSLLLDAMEFVTITLEDVVLLLGNKMDLIAVDKIETHLRYLQNNCEECKVYPDFVLL
                     CKIVDYTQIYVLQETFLHLKQYMIFGIYLERFFHEEYNEILKTRFDVCFEILRYLKKG
                     DVERFAESFSNIFKESLQYLKKVISSLNVDMRLKLGIL"
     gene            27366..28544
                     /locus_tag="KOU88_003218"
     CDS             27366..28544
                     /locus_tag="KOU88_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3213072.1"
                     /translation="MKYHIFLIITTILIIELCNIYICKIASFGNKNITIHKNYKYIFL
                     IKPLTFLIIIFTKLPLPLYYILFYIVSHKLLLSRKSSTNNHFIPNMAVISFCILHLIT
                     VSTISLVKNTSPDIIFANMTYKLISILIASILDFILWYSMNKIKEHIYIITQNQIEFS
                     LFLKFIWFTLGYILFDSIQITFAPPSSLTSYFILGSNILLILQLIIFINHIYSIEKNI
                     YLEKEHNRLKMIKQEQLLKVNLLKKKANIDELTSAYNRKFAFEKIQHYIDNNLLFSLI
                     YIDLDKLKTINDTYGHLAGDNYIINFSSIVIENLGIDDIFARIGGDEFIVIMPKSNEN
                     TTKEFIEKISKIMDNTISFSYGIVEVSSENKMTVEEIINIADIRMYTNKQNNHKRNNN
                     "
BASE COUNT         9801 a         4872 c         3175 g        10821 t
ORIGIN      
        1 ttacctgctg attgcccatt ttaaagtact taggatttaa ccttatacca tctaaccaat
       61 tttttctact ttcgtaactt tcacacttag gtttatttca tccttatgtt ttagtttggt
      121 tagctttagg ggtttccagc aattcaagta gtattggata ggttctatcc tatctctaca
      181 tataggtttc cctatatgct gactatttta gctactaact catgactaaa gtcacaagtg
      241 tgcgtagcta ttttttaatc aaactggaat acagactcca ttcctaggaa attggctgaa
      301 atatagtctg ctgtcaaaga tgctgtcatc acagaaatta aaacagatac tgaaaagttt
      361 ttatggactt cttcaagtga aaacataaca cccgccagtg gtgcatgaaa ggctgctgat
      421 aatccagcac ttgccccaca ggttaacagg aatttttcct ctgtcttccc tcggtcaaga
      481 gctctagaaa tacctttacc tgccatagca ccaagctgaa tggaaggacc ttcccttccc
      541 aaagcaagac cacccatgag tgataagaat cctccaataa attttgttgg caacactcgc
      601 caccatactt gttttatttt ccctgtcatt tccccctcaa gctgagggat accacttcca
      661 gaaatcattg gctcccagtc caccaacttt gatacaatcc atgcaagtac tgcaagtact
      721 gcaaaccaag ctattatttt tattgtagaa ccttctacaa attttaaaat ttggctaagc
      781 caagtaccag cctgccctaa aagtatcctg tataaaagca caatcaaacc agccacagcc
      841 ccaaccataa gtccttcacc aatcaaaatt acctgaaagt gctctgcccg tttgataata
      901 tgagatgtat cctttttcat actattcctc cttcatccaa taattctaca caatctgaat
      961 ctccaatgac taaagtcatg agtgtgtaca gatatttttt aatcaacaaa aatagatttt
     1021 tacttactaa atataagaaa ataattgctc aatttctcaa taaatgtgaa tttattcttt
     1081 taggtattta ttctccacag tcgtgcttct tccagcaaaa tatttattaa ttcttgcttt
     1141 ctctgtgtat agattttacg attgtcctca aactgtaatg ctaatttttg tttatgacta
     1201 tcatagagtt ttgctttgtc tgtaaaagta tttagataat ctcgaaaatt gatataatta
     1261 ttccatgcaa cactattcca ttcaacaaca tgaatatggt gagtacgagt atttttctca
     1321 aaatctccca tagcaaaaag taattgtttt ggtacatcct gacctcgaaa aacgattcca
     1381 cattgctcta acctttcgag gtataattta gcttcctcta aagaagcaac acctacaaca
     1441 atatcaataa taggctttgc cctaatactg ggaatagaag tgcttccaat gtgttgaata
     1501 tcaatggcag tcttatccca tatacttttc aataatataa tgacatcttt tgcactttta
     1561 tcccatatca tctgatgttc caataattta accataccac attttaaacc tatcactata
     1621 taccacctca atataatcca cctttatata tattacaatt ttttctatct tgataaacag
     1681 tgatttagct atttcacttt ttcttgacac tcgctacatt ccctatcatg aatagatata
     1741 attcctccac atttagaaca agtatatctc tccttctgct tttgcataaa cttctctaaa
     1801 ccgtactgct gaacaaattt actattttcc ataaggcttg cttgatatct cttgttataa
     1861 cttttttcaa gattttttat gagtttacaa ggaaaattga aacattcaaa acaataaaac
     1921 aacccttttt gacagacaca atcctttatt ttacacttac ggcagtgttc tggctttcct
     1981 gtatcgccat tcaaacaacc agcacatggc tttttgtgat aacaatgctt atagcaaacc
     2041 atacaattca ttccacaagg agcaaacata atcgtatcaa tactctcttt tggcattttc
     2101 ataacatttt actcctttca aaaatccaat ttgtcgaatt gttatatatt catattgtaa
     2161 cataaaaaat agctaaaaaa ttcatgcact ttcattgcca ataaattttc aaggaaatat
     2221 gaaagtttaa aactaagaat aaaaagagat aaaaaggaag ctactaatca aaatattcaa
     2281 atacaagtaa tcaatataaa taacttaagg tatatttaaa agtatatgat attaccagca
     2341 gttttaaata caaatataac cacacatgcc tcaaaaacac ttattacagt atcttagaaa
     2401 cttagacaat acataagatt cattaataaa aaagttctca atatagatat atttaaccat
     2461 gttttgaata gcagataatt atatgattaa aaattaaata tgacatagcg tttgtggaat
     2521 ataacaccta aattatgtta taataataaa acaggagtgt gatagtgatg gatgaaaaaa
     2581 tattagagtt attacaggaa atgcaaggta atattagtaa tatgcaaggt agtatcagtg
     2641 gtatcgaagg cactattagt gatatgcaaa gcaatattaa tggtatcgaa gacactatta
     2701 gtggcatgca aggcactatt agcgatatgc aaggcagtat cagtggtata gatgacacta
     2761 ttagcgatat gcaaggcagt atcagtagta tgaatggcac tattagcgat atgcaagaca
     2821 gtattactga tatgcaagtt gaaattaaag aagtcaatag taggttagac aatatggaac
     2881 ctgatattaa agacttaaaa actggacaag ttgaaactag tagtagactt gatactattc
     2941 agagtgatgt tacagaaatt aagtcagatg taaaaattaa cagaaataca ttagatacag
     3001 tgattaaaca tacctcttca ttagtaaaag atacatcaga tattaaaaat gatttaaata
     3061 atatagagat agtcacatct aagaattcga atgatattgc taaattaaaa tcagttaaat
     3121 aatataccat agtaaaaaat acctgaaaat ttcacatact tctttaaagt tataccaaat
     3181 tttatacaga aatactgatt atccgacaac acactttact tataaataat ttattaaaaa
     3241 aatactcatt ttatcctaaa attaacacga ctaaatgagt cttgatataa taataaaaaa
     3301 taagggagat tgaacactaa aaagttgtgt atctccctta tattctataa tatagttata
     3361 taatttttca gcctaaaata aaagtccatc tttgattaaa acacatcccc ttatcactta
     3421 taaaaggata aaatcttgtt ttcatttttc catttatatc ttcttgctta agagtaataa
     3481 ttttttcttt tgatacttta agtgtttggt taaatttaac caatcgacta agttttgttc
     3541 aacatctatt tttcatattt tccaatactt aatctatttt ttataaataa ttctttcatt
     3601 tctaactcac ttacattttt tacataaaac gaagcatata aatttcaacc ttatcttgta
     3661 tggttcttaa tacttaatga gtagcttaag tatcaaacat tataaatttt ccccttacat
     3721 ttaacactct taccatttcc aaaatataca aaatatattt tgaacatttg tacaatgatg
     3781 aaatacaata catgaaaata caatatcata actgttgtct aaaaatagaa gttcttcaac
     3841 ataacctttc acaaaaaaca tattatctaa atattttttg tctgctcctt gttttcctgt
     3901 ttgtagcata taaattactg catctaaaca tataactact cacatgaaaa aagaaaataa
     3961 acttccaaaa tacaagctct aaaaactacc tctaaagttg tataatgttt actaggaata
     4021 aggttgtata acatatagtt taaataatca ttttttaaaa ttgcaagtta ttgctttcaa
     4081 aattagatgt ttgtatatca aataaatgat taagaatttc taaatttaat ggctttataa
     4141 tgcgctccct ttctttggga taaaataatg ttgcacagat actttttcta aagataacaa
     4201 ttttattttt ctatcaattc caccagcata cccagtcaaa ctcccatttg ttcctacaac
     4261 acgatgacat ggaataataa tagagattcc attatgccct actgcaccac cgattgcttg
     4321 tgctgacatt ttagatattc ctttttgttg agcaacttta tatgcaattt ctccataagt
     4381 gattgtttta ccatatggta tttgttgtaa aattttccac actgtagtct gaaaaggagt
     4441 acctaccata tggagtgatg gtgtaaaatt gggttctttt cccgaaaaat aaatatctaa
     4501 ccatttcttt gtctgctcga aaattggcaa ttctttttct tgatgttctt ggtcaagatt
     4561 ataagcataa tacttttgat tctcaaacca aagaccagtt aacccaatat tatctgatgc
     4621 taaaagaata tttccaattg gactatggta atagctaata tattgcatac aattcctcct
     4681 tatattctga aaacttcact caaatcatta gacacttctt ttctatctac cattatgtaa
     4741 aaacatacta atataatttc cttctaacta cactttcgtt ataatatcta tcctcatatc
     4801 atattagttt tatatttacc tgcatctgtt catccttttt tccctttccc tttgatgaat
     4861 ataaaattca tacatttaag cttcctactg tattaacttt tatagaagtg tatattataa
     4921 ttttatcact aaataggcca aaaaaatatc gatatagcat caagtaatat cataatactt
     4981 tcaaatggga aaagtaagaa taggctgtaa aaaagaaaag tatttttatg ttagaaatcc
     5041 agtaaaatca ttagtagata gaataacaga aaacgaacaa tttgctattt atcattttac
     5101 acataaatat aattgacgca ataaagtgtt ttctattcta caacgattaa taaggttaga
     5161 aaaaagtaaa aatgaactgt atatgtatga agcattagtt tctgtttctt tcctttggct
     5221 tattatgata aaaaatattg ttttgctacc aataaaacac aaaaatataa ttaatatcca
     5281 tatgcaaaaa attttacgtt atattgaaaa atactattgt tttacattat attgaagggt
     5341 actattgtga aaacttaatt ttggagtact atcaagcagt ggtaatatca ataaatcaga
     5401 gtgctccaga tgatttgaac taagtttaaa tactatacct tataaatatt ttactgagtt
     5461 ttgtttatta aaagcaactc aatttctaaa aggcacaaat gagctaataa gtgacattgc
     5521 tataaaagtt gtttttcatc aaataatcta ttttagtaaa tgttttaaag aaaaaacggg
     5581 atattctcca aaagtgtaca gaaatataaa aaaagagata tgatttttta tttcttttga
     5641 ttatccaaag agtaaataaa aaatattgta aaaaacttac taacaacggc aatgctttga
     5701 actatggtaa tactttgaac ttttgattgg actttttttg ctaaaataat atatttaaat
     5761 agcaaagtaa tctgtttaat caataaaaaa taagagataa aagaaatcaa ctaaaacttt
     5821 tacctcttat tttgatagtt tatcagagct aatatttaca ctctttttat ttttgatact
     5881 tcattaaaaa tgatgcttac tctccattca cttttaattc ttcattaaaa atgatgctta
     5941 ttctccattc acttttaatt cttcattaaa aatgatgctt actctccatt cgcttttaat
     6001 tcttcattaa aaatgatgct tattctccat tcacttttaa ttcttcatta aaaatgatgc
     6061 ttactctcca ttcgctttta attcttcatt agaactatgc ttactctcca ttcactttta
     6121 attcttcatt aaaaatgatg cttactctct gttcactttt aattcttcat taaaaatgat
     6181 gcttattctc cattcacttt taattcttca ttaaaaatga tgcttattct ccattcactt
     6241 ttgattcttc attaaaaatg atgcttattc tccattcact tttaattctt cattaaaaat
     6301 gatgcttatt ctccattcac ttttgattct tcattaaaaa tgatgcttat tctctgttca
     6361 cttttaattc tttattaaaa ctgatgctta ttctccattc actttcaatt cttcattaaa
     6421 actgatgctt gcactctgta aactcataaa catccattaa tgcttcacca aatctttgat
     6481 agtgaactac ttccctctca cccaaaaatc tcaatatatc tttcaaatca gggtcatcag
     6541 ttaaatttat taattgatag tacgtagcca atgctttttg ttcagcagcc atatcctcat
     6601 gtaaatcagt taccgaatcg ccaaagacat taatataact tgtagtaaag tttactccat
     6661 tagaatctac tggctgaaga ccatgtccaa aattagcata attactacca agtccagcag
     6721 ccttaagttc ttctggagta caattgccta ttaattgata taacactgaa gaaattatct
     6781 caacatgagc catttcctct gtacctatat cagttaaaag tgcacgagat tttccagttg
     6841 gcatagtata tctttgttga agatatctag ttgcagctgc caactcacca ttaggtcctc
     6901 ccaactgagt catgatatat tttgccattc tagggtctgc ttgtcttatg ttaactggat
     6961 gttccagtgt tttttgataa atccacatat tatcttactc ctccttaata tatatttaat
     7021 aataaatcta attttaaagt ttaataattt tatttataaa atgatttgtc ccatggccaa
     7081 ggttcagata tccatgacca aggatattca cttgattcat atccaaaatt agttaatgct
     7141 ccatatttag attcataatc acacacagct tgtgtaaatt tatcgcagta tctgttgtat
     7201 gaatcaagag ctttcttatc ccttggattg ttatctaaat ataaatttaa ttctatacag
     7261 gcaaattgat attctgaaat tctctctaaa agttctcttc tatttaatga cattagtaca
     7321 tgttaccccc ttttttagct ctaactctat ttttaggatt tgcatatagc caatcattat
     7381 agttatttga ctctattaaa tctaattcag gaaataaagt acctcttttt aatgctgttt
     7441 ttggattgta tgtgtcatca taaatttgac gattgatgta tggtctagca aattcacaac
     7501 aatagtcttg tttatcctct tttaaatatc ccattaatta tcctccttaa tttttagaat
     7561 tttaaaatag cattattttt aaaaattgta tactggttct atattataac tggtagtttt
     7621 aataggtctt taataagatt aaatgattaa ataagtatct ttttttctta ttttaccttt
     7681 aaaatttttc taattaatct ttcataaata tctattttaa ataaataata tagagtttat
     7741 acaatttttt atagcttaat tactatttac tatatattat tcatttttaa ataaaatgtg
     7801 attatttttt attaaaaacg atataaatat acaatttaat actatttttt tataaataaa
     7861 ttcatattaa aatgcattca gttatataat tttgtttatc ctaagaatat aattataaaa
     7921 ataaaaaaag aataggataa ttttcctact cttttttctg tacttacata taatattaaa
     7981 actctttatt ttttaatata tattttaaat tttctttttt aataaatctt tttcttttaa
     8041 taaatctctt taattttctt cttctatatc agaatcaaag ggaatccatg cattaccaaa
     8101 ctctttatct ttaaataaat aagctaatcc agttatttgc ttcaatctaa gaatttcatc
     8161 aacttccata cccaggtgct ttgatatcca ttcatcagat tttccaattt cacaaagttc
     8221 agttataatt ttactcatta aatccacatt atgagaacct cttgcacgat tgtgtcgaat
     8281 agtacttgcc attctttcat caagagattt atcaattact gaaacaggaa gaagtccatt
     8341 ttctctatca tatatatcct cattttcaag cattactcta tatctatgaa aaccatctac
     8401 aataatatac ttatcctttt cctcattata ataacagaca attggcattg tatacccatc
     8461 ttcttttata cttttataca acaactgcat ttctggtggg gctactgcat ttggattata
     8521 gtcgttagat tctatctttt cgattggcac tgcgatgatt ccatatacag gacttttata
     8581 ttccatagca tcttaactcc tatctaatga attttttcat atttcttctt aatatattcc
     8641 gttctaattc tctgttcttt tgtaggacca aatcccataa atctacacat atggtcattt
     8701 tttaaaatac aataacacat tcttttccaa cttggtatat ctttggtaaa tttaatatca
     8761 tccgtatcat caggtatatc atccaaaaat atgactctac tctttttatc ttttgtatga
     8821 tttgaaactc catttaattc tattttataa ccttttctca acaattcacg tataactatt
     8881 tctgacaaac caccacctgt attctgccaa aactcaatag atgttgaaaa ttttttaata
     8941 tagctattcc ttatattttc aggtaaggta tcaagcaaaa aatatgtgaa acttttccat
     9001 gtgtgtccat atggcaattt aacactacga tatcccatag cttttgtttt gccataaata
     9061 gaagtaaaat taactccttg tactctagca accaatttca cccatacatc tgggtccaat
     9121 attctgtata aatttaaact ctcttttgct gaatcattaa aaggtgatgc cactctcatt
     9181 tttcttggag ctactccagc tttatagaat aagtcataaa ttttattata gtcatagtca
     9241 aatttatagt gtgctaacca tatatcttct atttcccaat catatatagg agatgccgtc
     9301 cagacatttt taaattcctt agttatccag cactttcctt tatatccatg ctgtttattc
     9361 acaatagaac aataacgttg tagagattct gctgctcgtg ttcctaataa gcaaacaact
     9421 tttgcacctt catgtatatc tctaatccat ctaccaaatt gttttgccaa actttcttgt
     9481 ctcattttat atttataata agtaaaagga ttattttttt gatttattat gtattctttg
     9541 actggcattt cccttaccca taactcttct ttctcatcat cccatggata ccaatacatt
     9601 tcataatttc ctacagcagt tcttgtagcc attggtaaac acacccaata tggttcaata
     9661 tcttcaatat tatcttcaaa tactttttca acatattcag tagtcaaact atattgagcc
     9721 tcaaaatctt gatgaaatac tcctattttg gaacttatat tattctttct cttataatcc
     9781 aaaactaaat ttagcagtaa accactatct tttcctccgc taaaagatac atagatataa
     9841 tcaaattcat taaaaagata agaaagtctt tcttgaaaag cttcaaatac atcggattct
     9901 aaatatctct tatccatttg aattatcccc tttcaattag aagtttataa aaccttacaa
     9961 tgcaatatta ttatgctttt ttagcagtaa tcagcataaa ttatacatta tttaaataca
    10021 caaatccaac taaatacata taattataat gtaattatac ttttgtatta taaactatat
    10081 tttatcatta ttttacattt ttttccaata tatataatta tcatattttt ctattagcta
    10141 aaactaatta ccttatattt ttacgtattg gtataataat acataaaaac ttgaataatg
    10201 cataaaaact tgacatactg ttgtcataat tactttgcta taattaaaag taaaaatgga
    10261 ggtaaattct aatgtatgaa cgtatgcttg ataaaagcaa taaaccctgt ttgtctcaaa
    10321 taatagaata tataggtaaa gatggatatg cacgattgtg taagttggaa acttacttga
    10381 aaactcaata taatttatca agagaacttc gatttccttt tggaaacaat tatggttggg
    10441 gttacaaata tagccataaa tcttttcatt tattttatgc tttttttgaa aaaggtgcat
    10501 ttactgttct gattcagata ggtgacaagc aagttccagc agtagaaaaa acgttggtag
    10561 ctttgacacc aaaagctaaa gagctctggg tcactcgtta tccttgtggc aataatggag
    10621 gttggattaa gtatcgtatt ttagaagatg cagacttact tgatattatt caatatataa
    10681 gagcaaaaaa atctccacct aaacaaaatt aacttttatt ttttgtgatt taaatatagt
    10741 gtatataaat tccattcttt ccatataaaa aaaataatat aaaaaatatc tattagtata
    10801 acttatttag tatgtcttat tctacttttt acagataatt aaaaagtttt atcataaata
    10861 aatcataact agacatccta gtaaatcaaa attaatttat tcttttttat tcgaattttt
    10921 gataatagtc cctatacata tgccaattat cattccaaaa attagaccat aacacattgt
    10981 gatacctaca tttcctttag aaatacctat agcacaacct atagccattc caagtatcat
    11041 gcctataaac atacatataa taactaaatt gttgttttta ttcatagttt tctccattca
    11101 atatatttta aattgcctag ctcgccttct tagcttaaaa caaagaaata taaattaact
    11161 ttctttcatt ctaatatctg cctgtataaa tgtcaaacaa cacatttctt gtcataacct
    11221 cctctttttg aagtaaatat aatctcccag acgcaataat atcaatttcc taaaaccatt
    11281 taagtaactt ttatatttac ataatattta caatcataaa ctatattgtt attcatttat
    11341 acatcataaa cactccctcc taatcattat tatacttaaa ataatgttca tttataataa
    11401 tatatctaac gcactttaat tgaaaaaact aaaactttgc ctttcattcc catatataaa
    11461 taagtatact ttttgatgct ctattacaaa tcaactgaat taattgatat aaattatcat
    11521 tttctgttga aaataccatt cgcacatgct atacttaatt gcataaatgg taataaatgt
    11581 catatgattt tacaaattat taataacaat tattactttt actgtatttt aaattttggg
    11641 gactaaatat caagaacttt ctaaaataca aagtacaaaa aatttatata agttataaat
    11701 ttatatgaac tagataagct caaacaatat gttatgtata aactgtgtag tattcggtta
    11761 taaatttata taaattatat aagctagata aagtattacc tcaactatat aagctagata
    11821 tataaattgc ttatataagc tagataagaa ttatttcaac tatataaact acatatataa
    11881 attacataca taagctagat atataaacta gatatataaa ctgcatatat aagctatata
    11941 agaattattt caactatata aactacatat gtaaaattca tgtaaattta ctaatataaa
    12001 tcaaataaaa ttactaaact ctctaaacta attttgtaaa acatactcta tttttaacat
    12061 ttgttacctt atacataagt acaaacaaaa tctaactaaa tgaaaggata atgtaaaatg
    12121 aatattttaa aaatgaaaaa aacagggata tttttaggag gagtactttt tggtactgta
    12181 ggtgttaaga tactttcaag tgattgtgtt aaaaaaactt gcactcgtgc aacagcagga
    12241 gcattgaaag ttaaagattc tgttcttgaa acaactacga aaattcaaga aaatgtagaa
    12301 gatattttag ctgaagcaaa agaaatcaac gagcaagaag acttatctac atctaaggta
    12361 aacgttgtac aagatactct taaatgcgaa caagaagttc ttaaaactga aactataaaa
    12421 actgtagaag atactaattc taatagcatt aaatgtgaag aaatcaaaga taacgtaatt
    12481 gaagaaaaaa ataatacttg tacaacagaa tagatttaat gattattatg attaataata
    12541 tcaggaggaa gtaaattgaa tttttatata aaacacgaaa taagaggtcg tatacgcttt
    12601 gacttacaac ttggcaaatt aaacaacaag cagtccgata ctctcttata ttatttaact
    12661 tctataaatg gtattaccaa agcaaaagtt tacgatagaa ctggtgatgc agtcatttat
    12721 tacactggtg aaagagaata cataataaga gaaatcacta aattcagttt taacaatagc
    12781 aaaatagaaa acctagttcc tgaacatacc agcagggaat taaacaatta ttatagagac
    12841 aaattagcaa ataaactgct agtcaaaagt atctccaaaa tattttttcc aaagtcctta
    12901 agattttttt taattggact tcattctata aaatatttta aaaaaggtct ctcttccctg
    12961 ctaaataaaa aaatagaagt ttctgtttta gatgccactg ctataggtat ttctattttt
    13021 agaaaagata tcaatacggc tggttcagtt atgtttcttc ttggtatcgg tgaactatta
    13081 gaagaatgga ctagaaaaaa atctatagac gacttggctc aaagtatgtc actaaacatt
    13141 gaaaaagtat ggttaagaaa aggtgacact gaaatcttaa ttccaatttc agagataaag
    13201 gaaggagatt tagtaagtgt aactatggga aatatgattc cattggatgg agttatagta
    13261 tcaggagaaa caatggtcaa tcaggcatca cttacaggtg aatcccttgc agttaacaaa
    13321 aaagaaggct cttacatata tgctggaact gtaatagagc aaggcaatat tgttatgtgc
    13381 gtcaaggaaa aagctggtac tactagattc cagaaaatag taactatgat tgaggaatct
    13441 gaaaaactaa aatcttctgt agagagtaaa tttgaacatc tagcagatac attagttcca
    13501 tacagctttt taggaagtat attaacctat gcaattacta gaaaccctat aaaatcactc
    13561 tctatattaa tggtagattt ctcttgtgca ttaaaactct ctatccctat ttcagtacta
    13621 tcagccatga gagaatgtaa caataacaac attactgtaa aaggtggaaa attccttgaa
    13681 ggtgttgcat gtgcagatac tattgtattt gataagacag gcacattaac aaaagctcaa
    13741 ccaactgttt cagatataat tacattccaa aattataata aggaggatat gttaagactt
    13801 gcagcttgct tagaagaaca ctttccacac tccatagcaa atgcagtagt ttacgaagct
    13861 gaaaaacaag ggcttagtca caaagaaatg catacagagg tagaatatat tattgctcat
    13921 ggcatttcaa caaaagttga tgataaaaag gttgtaatag gtagcaaaca ttttgtattt
    13981 gaagatgaga agtgtactat cccagacggt gaggaggata agtacaacaa tctatcagat
    14041 gagtattcac acctatttat ggcaatatca ggtaaattat cagcagttat ttgcataaat
    14101 gaccctttac gaaaagaagc aaaatatgta atttcaaatt taagagaatg cggaataaaa
    14161 aagattgtga tgatgactgg agatagcgaa aaaacagcta aatctatagc aagtaaagtt
    14221 ggtgttgatg aatattattc agaagtctta ccagaagaca aagccaattt tgttaaaagt
    14281 gaaaaactca aaggtcgcaa agtaattatg attggtgatg gaatcaatga ttctcctgct
    14341 atttcagaat cagatgtcgg aattgcaatg agtgaaggtg ctgaaatagc aagagagatt
    14401 tcagatatta ccatatcagc agataatttg aataatttaa tcgttttaaa gcagattagt
    14461 aataagctta tgaaaagagt tgatttaagt tctaagttta ttattggctt taatttaggt
    14521 ctgattttac ttggtgtagg tggatttgtt agaccaagta catctgcctt tttacacaac
    14581 acatctactg tcggaataag tttaaacagt atgacaaatt tattggaaaa caccaatact
    14641 tataactacc attaatctcc attacataaa acatatgata taaaaaattt ataattcatc
    14701 tttttaaaag aatatgtctt aaaattagct tttttctaat caaaattata taaagcatac
    14761 tttacaaatt ttaaactcaa cttatttcta ttttttacaa aaaaggagat gattcaaatt
    14821 ttcattttga aacatcccct tttgtaaatt tctttaaaat ttatatatta attatatttt
    14881 caaccaataa ttgtattttc aaccaatctt tcttcatagc attttaaatc attttgcttt
    14941 agataattaa attcagactc tacataaata ccacagccta ccaattcaat tgtcaaatta
    15001 ggtatatttt cctttagtat actagtctgc tcataaataa ttctttccaa taaatcaact
    15061 tgtaatatag aaaaatgctt cataatctcc ccatcactat ctatatcttt cttgatttca
    15121 taccaactct ttgacaaaat tcccttcaaa tcaatatacc ctagactcct caatatatct
    15181 atactatcgc tccatgcata cttactaggt ttatcaaagt atgattctag tttcttcttc
    15241 tgctcatttg taagtgaatc ataagaaagc ttcttattaa aatgtgcctt caaagaaatc
    15301 ttagccatag aatatggact tctaccagag tttaatcctg catttttgaa cttttcaatt
    15361 cctttatctt ctactgaaga ccatattgag tttattgaat ctgaatcatt gtatttaata
    15421 tcaagaccat gtgtaatatt tatatagttt tgtggaaata catattgata atagacatct
    15481 tttttatcat catatagaga gaagtatcca ctatcatata aatgaatatg cacctttact
    15541 tttaaactat cctctaaaat atttcgtcta aggttcggga tatttgcata catggttaca
    15601 tattttatgg catcaaagtt tttatttaat ggaacttcaa aactaatttc atctcctgtc
    15661 aaaagctttt tcacttcttc ttcattacaa tcatatagag aatatgtatt ttcaaatccc
    15721 acacgtgatt tcccatctaa actgcctgtt aatgctacct tcaaaatatg gttatctgtt
    15781 ttttgccatt ggtaagcatc ttggtcaaga aactctctaa tctgtctatt ttgctctttc
    15841 gcctgattta taacctcgtt ttcatcttct gtaatcccta catggcatct atttaagata
    15901 tttactatat tgcttccaaa tgggaatgtc catagttgaa aagctgctgc ctcaacctga
    15961 cacaaatatc taacctgatt taattcaatt tgatggataa gttttttctg atattcattc
    16021 atctgattac cactatctga catttgataa atcaattctc ccattgcaag attatctttt
    16081 ttcttatcaa tcttatcagt aatgataatt tgagtttcca tcatatcctg tactttttta
    16141 aatattatag aaatctcctc tgagttttcc atttttaagc ttccaaactt cgtgcttaat
    16201 tcagttaaaa cttccttcat ctttaattta cttatctcat tttcaaaaat atcttgattt
    16261 ttaactgtac tatcgaattt ttctacaaat ggtataacag attctttcaa agttttatct
    16321 ttaaattcca ccatttgagt attcaattca tctaatttct taatattatt ttctttatct
    16381 ttaattgcct ctttaactac ctctatttta ctctcaaaac tagattttac attaagacaa
    16441 ttattaacac cactaatcgc agtatttata agagaacaag cagaacttcc aatactcaat
    16501 gcatttttaa ttttagatgt cttttgctgt ctttcaatag cttgtttact tttctctagt
    16561 gcagctaact tatctttttg ctgtttatta ttgtaatttg cctccaacat acctatttct
    16621 tttttctgga tttttgtgta aatttcctta tactcgcttt cacttaaccc ctcttttgct
    16681 ctttgaatat cgtcagcttt gtctgcatag ttatcatcat ctatagactt aactataatc
    16741 tccttaattt ggtcaaattt agttcttctt tcttcatcaa cacctgccaa attataagtc
    16801 attttatcta aagcattttt tctatcttca cttagctgtt ctccaagtac aaatctcata
    16861 ccatcagaat ccaatttaaa atctgaaaaa tcaaccatcc tgttagtcca ttggtattcc
    16921 tcttctttag ctgaaagatt ttccttcaaa gattttgcac tgtcaaatgc ccctagacaa
    16981 gcttgaccaa caccactaaa tgcagtcagt aaactcaatg cgctttgtat tccagaaaga
    17041 attaactgtg ttttcatttg ttcctcaagt tttgcctgtt tcttttttag ttcctctatg
    17101 tcttcttgtt catcttcttt catctttata atttcttgaa tcaacaggtt catttttgca
    17161 ttaacagaaa gcattttatt ctcaagttca ttttttaaaa cctctatttg ttgatttcca
    17221 gattcaattt gagttaggat actttcctta tatgtattga aatatccttc ttttaactca
    17281 tctttctttc cttgttccaa ttctcttaag gtcttatcca gatagtctgt caaagaacga
    17341 atatctgtaa cacgatttcc tccaatttca ctttcttcaa tcatctgcac ataaaatgct
    17401 gtcttctgct caagtgcaaa taaaatcata ctccattcgc taaaattctg attttttcct
    17461 acaaaagatt ctattctatc agactgcatc aatttattta taaggtattc atagatttcc
    17521 tttgcctctt tataaaattc tttctttata ttcatgtcat ccatagaaag tactgcttta
    17581 tttttcttct caaaactata gtacttctga agtatttctc tatttaattg catctctatt
    17641 ttctcaactg cataaaaaat ttcataaata tgtgaaaatt ctaaaatatc agcttctaaa
    17701 attcctactg cacacaacag tctaagattt ctataacctt taattccaga aaaaccaaat
    17761 ctctcgaaaa attcatagaa gaatgtatct attgacaaag aatactcctg ctttaacaat
    17821 tccttttctt ttagtgcatc tccagagtga ccggcttttc cctctgctcc ggctgaacct
    17881 gaatcttcac gtttgctaat tgtccagtcc ttatgttctt cataaagagt atttaatttc
    17941 tctccatcat ctgctgcttg cttctgattt aaagcatgat taaacacata tctatcaaaa
    18001 taatagtagt ttctatcact attatccatt ggaggagagg tacctatata tcttattgtt
    18061 tcttcatata tacctctaat tccaccaaga cctcctgcac caccagctcc tccagagcct
    18121 ccttttcctg ctaaaccatg atttccatct tttttactta tagcactttt taataaagga
    18181 gcttttccaa ggagataaac ctgtccagac ttgcttccaa gacctgcatt tccaccatta
    18241 cctcctgtgc ctccagttcc accttgtttt cctttttctg cttttacaac atagtatttt
    18301 gtacctttaa cattagcaaa ttcttttgac tcttttttag aacctatttt agcatttgcc
    18361 ccagcttctc cagttatccc tgtatctcct ttttttccat cttgtccatt tccaccacgt
    18421 ccaccatcta cgtaaagttt aagttctcct cttttttcta tttctttaaa agataatatg
    18481 atatcacctg aagtacctgc attattgcca tttcttccat tcattccgtc gtaaatagaa
    18541 ctttctccaa ccaatttttc tgcatcctta ccagatacgt tgattgaata agtcccttct
    18601 ggtatatgta atttttctgt aagtagtaca atattcttac ctgagaagac ttctttctcc
    18661 atattacagt caattttcaa ctcacaatct ccatacatat atatagatga caaaatatta
    18721 agttgataac cagatattat tttagtcaaa tccgataaat tcactttagg tataggaata
    18781 tatatagaaa gtacattttc tttctcatat gattttatat atgtacaact ttgaatcttc
    18841 tctatcctat actctgcatc ttcaagcttt ttggcttctt cttccctata ttcttcttct
    18901 gctatccaat atttgatatc ttttaatgta tcttctaaag tattttttag caatgatttt
    18961 aacaactcac ttagaccaac aatatgagtc tcactacagt aactatttaa ctctaaaaga
    19021 agacgtgttt cttctaatat attcactttc tgtacgccat caccatatga aagttcttgt
    19081 acaaactcca taagctcttt catattatta gtcctactac ataaatctgt atacatctta
    19141 tctaattgaa tctttttatc ttttagacta tttatagaag atagaatgga aatagaatct
    19201 tccatacctt ttttaacact ttctatataa ggaactaaaa gtttttctag gtctttatag
    19261 gttacatcaa cagctttttg tatttctatt ttacaagaag ctgtaagcat caatcccaaa
    19321 tctgtttttt caaatgtttc aggtagattt ttcatttcat ccaacaactt ttctggctgt
    19381 ttatctagtg gattacataa tttaatagat acaccatctg ataatgctac atttaataag
    19441 tacactaatt ccttacaacc gtcgtaatct ttctcttgac tatctaagtc ttcttttgct
    19501 ttttccaata tatttcttat tttttcttct gttacattac cgattagtgt tttaggtatt
    19561 ttattaataa gaaagaagaa attttcttta tactttgcat aatcaccaag catatctttc
    19621 aaatttttgc ctgtttctat caataatgta tgtctagagt ccagtaggga ttgatagtct
    19681 aagataacta ccatcccttt cacctttgaa gatgtggaaa tagtttccct tacaagcata
    19741 gcaccagcaa tcatatactc tgctccacgg ttgtcaaaaa aacctgggca atcacataat
    19801 gaaaaatctc tatttgcaat atctacaact tctggacata aagtcttaga atatacacca
    19861 tttccaattt cgacagctga atcttttgca gttatatata tttgtccagt ctcttcatcc
    19921 gttttttctt ccatcacaca gccttttaaa taatttatac aagtactctt tccaacgcct
    19981 gaagcaccta ggaataacaa aattgacttt tcttttaagt catattttct aagctcgtct
    20041 cttccttctt ccaaaaggtt tacgatttca ctataaagtt tatttgccat acatccatcc
    20101 ctttctatat ttcggaacaa tagccttgat atttttcttt aataagattc tcttctacct
    20161 ttgaaacagc tgttgataac ttagtatttg gagcattaaa tcctccattg tctcctctat
    20221 ctccatattc agcgtattct cttgctggtc ctgttttacc ttcattccag cttccaccac
    20281 taaattctat atgatattta attatactat ctaacttata atcccaactt gtaaaatatc
    20341 ctgtatagta tacagtctta tctataccac ttggagaaaa tgaaagtgta ttatatccgt
    20401 gatagccacc acttcctcca tatccaccta aacctggtct accatttgga cctgcttctc
    20461 catctttcac tgttatatca caatgattaa ttattctatt tttttgttcc tctgaatctg
    20521 aaatgaagta aatattacct ttcttaccag catttccacc tcttccagca tttccaccag
    20581 ctccaccttt ttcacctttt ttgccacttg tacctttttc aaaataccct ttaaacatct
    20641 gtccgtggaa ataacttgta tatcctgcat cagctccatt acttccagaa gctcctgttt
    20701 caccattttc tccatctatt cctttagaac catttcctcc atttgcaatc agtgttagac
    20761 gataatttct aatttcttct ttaatatata agtaaatatt acctgcatct ctaccatctt
    20821 caccattttt cccatacata gaattatcta caagttctcc gctctttcca cttacattaa
    20881 tttttacatt actacctaca tcaagattgt tagaagcaag aataatattt ttctctgatg
    20941 caaagttcat tccaaggtta tcatccatat aaatagtatc tttagcaaag aacataaaag
    21001 tagaaacatt gtcatctact tttctatttt tgaaatattc caatacactg ctaattacta
    21061 agtttggaat taatgctctt atttcaatac ctttcttatc attaatatta attgttttta
    21121 ctataaatgg atttaaaatg tatttaccaa taaattctct aattatctca ttaccttctt
    21181 ctccatatgc acttaatctt gttatactgt cttctaactc ttcattttgt gtaactgtaa
    21241 catttgtcaa aattgaatta aaatcactta cactatatac ataatccttt ttatttgcaa
    21301 cttccattaa tttttctcta tttggtaatg taaatacctg tttttgcact tcataagaaa
    21361 ctaaaacttt ttctaaattc tttcttatta taatgaagtt ttgttccatt atcttcttac
    21421 ttgccttttc tataataaat tccatatgta cagaaggtaa taaaatttcc ccagttccat
    21481 gttctgtata tttacttaaa gcatcaatta tatctaagtt tccttttatc ttattttgta
    21541 atttcatgca actatcttgt aagaataatc cactttgttt ggctaatacg ttgataaatc
    21601 tctctatagt aagacttgtt gtactttcca accagttttt aaatactttt acaacctcat
    21661 catattttgc tatttcttga atcattgtta tacttccaat aatattgata aaatcttctg
    21721 tatacgcctt aacataatct tctaggctag atacgatatt gttttgaatt tcttttatca
    21781 acgtatctaa aactaatctt gcatctgcac taattggata ttggaatgct gatgtcttat
    21841 ctttaacttc atctaattct agtacttgct ttaataagcc ttccctctca tctgatgcaa
    21901 gtggcttaca aagatgaata ttttttccat tatcttttag caattcttca aataaccaag
    21961 ctttttcctc tatattactg tctaaatttt cgcataattg ttcatatttt ctttttataa
    22021 cattatatat ttgtttttct gttcttccta agaaactttt tgaaatgaaa aaagttatac
    22081 tacccttaaa attttcttta tgaagacaca tatttaactg ttggaatagg tctagtactt
    22141 ttgtaagtct agaatctaat atatctgctt ctggtatcaa tacaattact gcacatatag
    22201 atgcagaatt tttaaatact tcacctaatg aaactgctgc actaatatca tgggctactc
    22261 ccctattgtc gctaaaacct gcagtatcac ataattttgc atccattcct tctattggtt
    22321 ttctcatatt tacaatgttc gggtataaag tttgagaaac agctcctgaa ccaatctctg
    22381 ccacagggtc taagcaatca atatatgata taccagtatc ttcatcttct acttccatca
    22441 ttacacatcc tgcaagatag ttaattgcag tacttttgcc acatcctgtc ccaccaagaa
    22501 ttagaattaa attttgattt tcagccttat ttattgctac ttttccttca tttaataaga
    22561 gtgttatttc ttctaaaagt tgattgttat tttctggcat ttattttccc ccttggttat
    22621 atattttatt taaataaagt ttaatccctt aagtagattg caaagttttt agactatatt
    22681 taaatttgtt ttttattttt tatttttaat aaatttgctt tttcactaaa tttgcttttt
    22741 cactcaataa ttattcttct ttgtttatta aaataactgt gttgtataat ataatcttta
    22801 ccaacacagt tattttattt aatgcgctta ttttattgta ttttatgtaa tacagttgtt
    22861 ttttatatta tatgtccatt attttcctgt ggttattaca tatagatttt taattatatt
    22921 tgtaccatta atttaaacat tcctatacta ctgcttaagt tttacaccta taccagcttg
    22981 aatattttat ttttatttgc ttaaatagtt caactatact ggtttaaata ggttatcttt
    23041 atttgcttaa atagttcaac tatactggtt taaataggtt atctttattt gcttaaataa
    23101 gttcaactat actggtttaa ataggttatc tttatttgct taaataagtt caactatact
    23161 ggtttaaata ggtttccttt agtttaaata attcacctat acctacttga atagttcact
    23221 tttatttgct taaattctat accaataccg gcttaaacat tatactacca tgattgtatt
    23281 gtctatcttc aactacaata aaaacaggtt ctaaatcttt agtagatgtt atttttaatt
    23341 ctaaaaaaat attatcagtt ggtaatattt ttacatcata attatttaaa ttattattcg
    23401 tgatactatt aaatacatca ccttgacgtt caaaaaaaac attatcaact attacaaaat
    23461 aaacatcttc ttttctacta ttttcaacct ctatagtatt ttgtttagtt acatttagtc
    23521 tcatcttcca cctcctatta atattactta attatattaa tacttgtaat tgttgcatta
    23581 tgttcatcac aaggaagagg tttaaaaaca actatctctg ctaaataatt ctgtggagga
    23641 tttgtaactg aagtagcatt gcaaataaat ttaaaatttg ttcctgctac aacttgagta
    23701 gaaacaataa gtggttcata accaacccct tctaacattc ctacagcttc attaaatact
    23761 tttaaatctt cttcttcgac agctctgaat tttgaccatc caccaacaaa aagactcata
    23821 taaaaacctc ctttatatat atatttattt atatatagta gtaccaattt tctcaatatt
    23881 caatatttta tgtgtaactg gtcaatgaaa atgcataact ggataaaaat acttataaaa
    23941 taacttaact ttacatataa atagcttact ttacatgtaa taagattatt ctacaatatg
    24001 aaatgcatct tgttttgaat atattctaaa tacaataatg gatattttca attattataa
    24061 ttagaaaata tccattactt aacttgtttt atttaaaatc acatagagac tttattattt
    24121 tttttattgc atgaatagct atttcaggta tcataaggtg atataccccc tccttgaaac
    24181 cacaaaaaac atgacaaact ttacgaatct tggcttaaaa gaccacaggt acattcctta
    24241 tttgtggatt ggagtagcca taacaagcaa attttacaat ttttatgatg acaaaaatca
    24301 ataaaatcgc ttagtatata acacgaaaca ctacttgtta ctattaagaa tagttagata
    24361 ggaagtatgc attataccaa taaaggaatc aataaagaaa gttaaaacat ccctacaaat
    24421 taaaaatctg ttacattttt ctatatttaa acgttattta cttacaattg gagaaataac
    24481 aggttttcct tctcggtcaa gtaaaggcgt aaatccggct gcattgccat aatagtggaa
    24541 tacatagttc acacctgttt ctttatccac ccaaatctcc gttgcattta tttttccttg
    24601 tgaatatact ttttcaaatc tatcttttcc cattttataa tcccccatat ttttgattgg
    24661 tctatacctt cttcacttaa gtcgaaaaaa tacataactt atttttttaa ttctaatatg
    24721 agcacgtaaa aatgtcaaac agcttattta atttcataac ttcatgttac tgttcgtaac
    24781 cttgtctgtt tacttacact gcattacagc accattttat cctttacatt attgtattgc
    24841 acacagtaaa aatgcttact ttatgggatt tttcaactaa aaaaaggatt ttatctccac
    24901 aaaacattta ctatttgtta caatatacct aattttaatc tcatatcaac atttaatgaa
    24961 gatataacct ttttcaaata ttgtaaagac tccttaaaaa tattagaaaa agattctgca
    25021 aatctctcaa catctccttt ttttaaatac ctaagtatct caaaacatac atcaaaacgt
    25081 gttttcaaaa tttcattata ttcttcatga aaaaatctct ctaaatagat tccaaatatc
    25141 atatattgtt ttaaatgcaa aaatgtttcc tgtaatacat aaatttgtgt ataatctact
    25201 atcttacaaa gtaaaacaaa atctggataa accttacact cttcacaatt attttgtaag
    25261 taccttaaat gagtttctat tttatctaca gctatcaaat ccattttatt tcctagtaaa
    25321 agtactacat cctcaagagt aatcgtaaca aactccatag catccaaaag caaactcaac
    25381 cttttagctc cttcttctgt atttatataa tcatcatcat attcagaaaa aagtgttata
    25441 tatgttccct tgccattaat tgttttagca attcccaatt catttagctc attataggca
    25501 cttctaactg ttggaagaga tacattatat ctattaatta tcgaagtaat tgatggtaga
    25561 caatctccta ttttaatatt gccttcaaaa atttgacaaa ttacatctga aacaattaag
    25621 tcatataaat aacatttttc caacgttaca gaattaaaac tacttgtatc tatactttgt
    25681 ggagcacgat tttctaccat tttaagtatg gattctctac aagctttata catatatgtt
    25741 aatagttttt taaattcaat tagattcccg tccaatccat ataagtaagt ttttcttacc
    25801 tgctctatgt atttattacg aaaaaagtct atacaacaat tatccaagtt atcgaaatta
    25861 taggccaatt gtgaaataat gacatcatgc tgaataatct cacaaaaatg gtgaatcagg
    25921 aaattatttg ttttacttat tagtttattt atatatttta gcctttgttc tttaaagact
    25981 aaataattag aactattttt ttccatacaa tcgataatct cgtttaattc ttcaaagtct
    26041 ttagatgtaa atcttttaat attgtacata gcaatagaag gaaatattaa actaaaaatc
    26101 ttatatattt ctgatatttg taaaatcttc tcatataata agtcagattc tattgattgt
    26161 ttactcgtac tctggattaa aactggtcta gaaccagctt ttgtctctat aaagcccttt
    26221 tctgagagca tttttattac agtttttata gtattttttg ataccatata ttcttctgac
    26281 atgcttttta tagaatcaag cctatctcca atagtaattt taccagtata aatttgttga
    26341 attatatgct caaaaataac taaatattgt ggttttctct tcatattttt cctcttcgat
    26401 aaattagatt tattgttttt tgtaaggtat atttactttt atttaatagg gcaaaatagt
    26461 tgcttatttt ttcctcataa tctataatta atataaacca tttatatata tggtctaagt
    26521 tttataatac tgtaatgcag taaaatagca tattgtagct atactacagc aaattaacat
    26581 accattgtag tatattaatt ggaataattt taagtacttc aaaattccat caaaacatat
    26641 atgtgttttt gatattatgt atattcgtta atagaatagc tatacttgtt ttacataata
    26701 aattatatga tacttgctat atgtaattac tatatttaat acacataact attatactta
    26761 ctatatgtaa ttactatatt tgatacacat aattatgata cttactatat ataattacta
    26821 tacttggaca cataactatt atacttgcta tatgtaatta ctatacttta tacacatagt
    26881 tgttatacat gctatatata attactacac ttggacacat aactactata tttactatat
    26941 gtaattatac tatacttgga catatagtta tcatacatac tatatgtaat tactatactt
    27001 ggacacatta ttatatttgc tatatgtaat tatactatac ttggacatat agttatcata
    27061 catactatat ataattacta tacttggaca cattatcata catactatat gtaattacta
    27121 tacttataca catagttatc atatatacta tatataatta ctatacttgg acacatagtt
    27181 atcatacata ctgtatatta agatataata ctttttaaat tttatataac acagacacat
    27241 gcaataaaaa agaaggtatc cataataagc tctttgcatg tacctaaata aaaactgtaa
    27301 aatagaatat ataaaatcta atctatttta agtaaataca atttcacttt aaaagaggat
    27361 gtactatgaa ataccatata tttttaatca taactactat attaataatc gaactatgta
    27421 acatttacat atgcaaaata gcatcttttg gaaacaaaaa tataactata cataagaatt
    27481 acaaatatat ttttttaata aaaccattaa ccttcttgat aataatattc acaaaattac
    27541 cattaccact atattatata ttgttttaca tagtaagtca taaattgctc ttaagcagaa
    27601 aaagttctac taacaaccat tttattccca atatggcagt aataagtttt tgtattttac
    27661 accttattac tgtaagtaca atatcacttg ttaaaaatac aagtccagat ataatatttg
    27721 caaatatgac ctataagtta attagtattt taatagcttc tattttagat tttatcttat
    27781 ggtactctat gaataaaata aaagagcata tttatataat aactcaaaat caaatagagt
    27841 tcagtctatt tttaaaattt atctggttca ctttaggata tatattattt gatagtatac
    27901 aaattacatt tgctccacca agttctctaa cttcctactt tatattggga agtaacatat
    27961 tattaatctt acaactaatt atattcatca atcatatata ttccattgaa aaaaatattt
    28021 atttagaaaa agaacataat agactaaaaa tgataaaaca agaacaatta ctaaaagtaa
    28081 atttattaaa gaaaaaagct aacattgatg aattaacatc agcatataat cgaaaatttg
    28141 cttttgaaaa aatacagcat tacattgata acaatttatt attttcattg atatatatcg
    28201 atttggataa attaaagacg ataaatgata catatggaca tttagctggg gataactata
    28261 ttattaactt ctcaagtata gttattgaaa acttaggaat agatgacata tttgctagaa
    28321 taggaggaga tgagtttata gttattatgc ctaaatctaa tgaaaacacc acaaaagaat
    28381 ttatagagaa aataagtaaa attatggata atacgatatc ttttagctat ggtattgtag
    28441 aagtttctag cgaaaacaaa atgactgtag aagaaattat taatattgct gatattagaa
    28501 tgtacactaa taaacaaaat aatcataaaa ggaacaataa ctaaaatgaa tatttacatg
    28561 agcttacttg tagtctcact atgtttttta tcttattatc tctatcatta taattttttt
    28621 aaatatctgg acataatgat taataactct aaaaataaat acacagtat
//
LOCUS       DAFAZV010000054        28006 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFAZV010000054 DAFAZV010000000
VERSION     DAFAZV010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 28006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28006
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.054"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            2..1228
                     /locus_tag="KOU88_003219"
     CDS             2..1228
                     /locus_tag="KOU88_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018591490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC/Rec2 family competence protein"
                     /protein_id="HBK3213073.1"
                     /translation="MTNNTKNDEELNDKIITIQGVVKGKIEKKRYNQYKVGVFLINDY
                     TKNKNLKIGQKVNITGKFKSLDKMKYDDFDYGRYIKSTGYKGIVYINNYKIIDKNKLY
                     SLIGEIKFYISKTYRYLYKKNSDFINSILLAEVENLTEEQKEIFTRTGTSHVISISGL
                     HTGILCVIISFLLRGINKLYKLLILSIFITLYCIMVGASPSIIRSIAFVMIFYLSIFI
                     DRKKDGISALSLIGIILIMNNPYVIYNVSFQLSFLATLSILIFYNKINSIIKLSMVSL
                     TISSNILTLPIIYYAFKGIPLLSIIGNLIIVPFVGVIMYLSIASLIVFKVSVVIAKII
                     SFFNSTLIESIFFLLEKISNLSFAYINIESPKFYIVVIYYIGVFFYIFYIEGKEIKEQ
                     ENELQGYYKECKREKL"
     gene            1182..2225
                     /gene="holA"
                     /locus_tag="KOU88_003220"
     CDS             1182..2225
                     /gene="holA"
                     /locus_tag="KOU88_003220"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBK3213074.1"
                     /translation="MNYKDIIRNVKEKNFEKMYLFYGREYYLIENAIKAFKDSLNEGM
                     LDFNLDIIDGKEIVLNQLISSIETLPFMDDRKIVIIKDFELLKGKKKNFTDSDEKYLI
                     EHLDNIPDTTTIVFVVYGDVDKRKSLVKKIGNNGIVFDCDKLSDMDLFKWIKKSFALN
                     DVIIDNSQIMYFIEQEGYRDKSSEKTLSDLENEINKISSFVGKGNNVTNDVIDKLSQK
                     KVENDIFKLIDYIGEQNASNAMKILNDMIQEGESVLGIFSMIARQFKIIMQVRQLQLD
                     GYSTKLIADKLKMHQFVVGKALKQTKNFSDDIIVEILNYILESDYKIKTGLIRDTLAV
                     EMLVSRYCKREAI"
     gene            complement(2412..2678)
                     /gene="rpsT"
                     /locus_tag="KOU88_003221"
     CDS             complement(2412..2678)
                     /gene="rpsT"
                     /locus_tag="KOU88_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBK3213075.1"
                     /translation="MANIKSAKKRISVIEKKTALNRVRKSQIKTAIRRFEDAVAAGNR
                     EDAVAKFQYAQKRIYQVASKGTIHKNAAARKVAKLAQKLNGMNA"
     gene            3277..3798
                     /locus_tag="KOU88_003222"
     CDS             3277..3798
                     /locus_tag="KOU88_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213076.1"
                     /translation="MDIAKLILNPARLRILQYIRLHSSVRTSDIVKYLNDIPRATVYH
                     HVKILEENNMIEVIKENRVRGTIEKVYALKEYTTSMEGETFVALSTAFYVGLMQEMNE
                     YFSRKEQDHKKDNVFFSSALLYMSDNEYENLLKSIADLLKPYIEQKPKSNLKLRKLSI
                     ISSPPVADNDKTK"
     gene            3832..4608
                     /locus_tag="KOU88_003223"
     CDS             3832..4608
                     /locus_tag="KOU88_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3213077.1"
                     /translation="MKFHEFGNKNRPHIMLIHGGGNAWWNYLRQAEVLSNKYHVILPT
                     LDGHGEEYETTYISTEDTADKLISYIDENCSGHLFALCGVSLGGQIVMELLSRKPNIT
                     KKAIIDGSICYPRPLMARFCIAGIRFFGGLLFSEKACRFQIAMMPKLLPENMQYPDEI
                     KAYYMTDMPHVRKETFYNMYRTYMMNYTLKENVKKTTAQVMYWYGEKEMKCVKKSAKM
                     FQSYVPSCEIYEAKSYNHGYLSLYLPNEWLEIAEPFFQKE"
     gene            4950..5903
                     /locus_tag="KOU88_003224"
     CDS             4950..5903
                     /locus_tag="KOU88_003224"
                     /EC_number="3.4.24.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPR endopeptidase"
                     /protein_id="HBK3213078.1"
                     /translation="MISVRTDLALEASEMCEKSQEGSSIPGVKIETKELENCIVTKVE
                     VIDRQGAEIMNKDIGKYITLESNLMKFDDDESREEMISYLKEELVDIFGQDKNKKTLV
                     IGLGNRNITSDALGPKSVSKTLVTRHLFKNYNKDYDDDFTEVSALSPGVMGVTGIETS
                     EIVKSLVEKVKPDRVVAIDALASRKMERVNSTIQISTAGISPGGGVGNTRKSLTKETL
                     GVDVIAIGVPTVVDAATLTIDVLDMAIDNLIAQSEETESFYEMLKKLKEEEKYHLIKD
                     SLDPYDKNLIVTPKDIDDTIENLSIIISEGLNRSLHPGRLV"
     gene            5921..6940
                     /locus_tag="KOU88_003225"
     CDS             5921..6940
                     /locus_tag="KOU88_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage II sporulation protein P"
                     /protein_id="HBK3213079.1"
                     /translation="MFKKCIKVVTLTFILVCILPGKSLALNQDDFLKFLVNSSYPEAK
                     VEGNDTENKKNNKNKETSKENKEESKEENTKSKDASKVDNKKESEKEYIKLYVGKENV
                     PDIESKNSDTTETNTTSSSDYKDDLRVTKENPRILIYHTHGCETYSNSPDGNYHSRDK
                     KNSVMEVGSALTSALDSKGWGVVHTTKYHDYPSYNNSYASSLKTIQSILPKYNSVDIA
                     IDLHRDARDLTNPATKEKDHLKYTTMINGERVSKFFFVVGGKNTNRKQLRALAEDITA
                     FAEKKYPGLVSPIVEKDYARFNQFAVKNHMLVEIGNNATSVEESKATTKYLAEILDEY
                     FKQKN"
     gene            6971..7222
                     /locus_tag="KOU88_003226"
     CDS             6971..7222
                     /locus_tag="KOU88_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213080.1"
                     /translation="MSRLEKNIESKSKLRKYKYIMRILFLITMIICTSVCVFIVDSNA
                     KSMLGMKQYDFPSIKFDITKFDFDIPNFDIHEIIKKFNK"
     gene            7504..9309
                     /gene="lepA"
                     /locus_tag="KOU88_003227"
     CDS             7504..9309
                     /gene="lepA"
                     /locus_tag="KOU88_003227"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBK3213081.1"
                     /translation="MDNKQSRTRNFSIIAHIDHGKSTLADRLIQQTGLVSERDMKSQL
                     LDNMDLERERGITIKLQNIRLMYKAKDGNEYYLNLIDTPGHVDFNYEVSRSLAACEGA
                     LLVVDAAQGVEAQTLANVYLAIDQDLEILPIINKIDLPSARPEEVKNEIEDLIGLDSS
                     EAPLISAKTGLNIEDVLEDIVKNVPPPKGDNEAPLKALIFDSYYDAYKGVVAYVRVFE
                     GTVKKGMTIKMMNTNKKFEVTEVGVMAPGQTELSELSAGDVGYIAASIKDIRSCRVGD
                     TITDSNNPTEEPLPGYKKATPMVYCGIYPGEGEKYENVRDALEKLQVNDAALEYEAET
                     SAALGFGFRCGFLGLLHMEIMQERLEREFNLDIITTAPSVIYRVTKMDGEVVMIQNPA
                     NLPEPSEIKMIEEPIVKGDIIVPKDYVGVVMELCQERRGNMLNMEYIDDRRVMLHYDL
                     PLNEVVYDFFDALKSRTRGYGSLDYEVKGYVASTLVKLDILINKEQVDALSFIVHETR
                     AFPRGKAMCEKLKGEIPRHQFAIPIQAAVGNKVIARETISALRKDVLAKCYGGDISRK
                     KKLLEKQKEGKKRMRQIGSVEVPQKAFMSVLKLDE"
     gene            9458..10795
                     /locus_tag="KOU88_003228"
     CDS             9458..10795
                     /locus_tag="KOU88_003228"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBK3213082.1"
                     /translation="MINIEIPKKVDYIIKELEKNGYEAYIVGGCVRDCLLERVPNDWD
                     ITTSARPEVVVELFEKTIPTGIQHGTVTVMIEHEPFEVTTYRIDGNYSDGRHPDSIEF
                     TNNIVKDLSRRDFTINSIAYNSKTGLVDPFNGYEDIQNKYIHCVGNPVDRFEEDALRM
                     LRAVRFSAQLNFKIAEGTKQSIHKKADLIKNVSIERIQTEFNKILVSDSSKLNLLKST
                     GLLKFIIPEICELEDVTQHNPYHIYDVQKHTLIATEAIEDELYLKLTMLFHDLGKKVT
                     KTTDKNGVDHFYTHSRESVKIAKKILKRLKYDNYTINKVLILIQYHDYRIEPKRKIIK
                     KLLNKLEDVGLFEDLIKVNWADTLAKNPKYAKQKILNLIECEKEFKHIINQKECFNLK
                     DLAINGKDLISIGIKPGKDIGYILNKMLEIVINNPELNEKEILKEKALNIYTF"
     gene            11028..12341
                     /locus_tag="KOU88_003229"
     CDS             11028..12341
                     /locus_tag="KOU88_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK3213083.1"
                     /translation="MHTQLQKTIGLSAALSTVVGMVIGSGVFFKPQAIYTTTNGAPGL
                     GIIAWLLGGFITITAGLTATEISAAIPKTGGMMIYIEEIYGEKLGFLTGWMQTVLFFP
                     GTSAALGVIFAQQASELLGMSPNNMANVLPIAIGVILFLALLNIIGSSLGGKVQTVAT
                     IGKMIPLILIIVFGFIKGQSSEVLNPFVGDGVNASNALGQVLIATLFAYDGWINVGAI
                     SGEMKSPEKDLPRAIVGGLSLVMAVYIIINIAYLWVVPASELATVTSPATLVATRLFG
                     NIGGKVITVGILISVFGTLNGYLLTGSRIPYTLAEMGTLPASKTLLKVNSGGSPVNSI
                     LLITVLACVYALSGQFNLLTDLTIFSIWVFYVLTFIGVMRLRRQKPDLHRPYKVPLYP
                     IIPIIAILGGLFVIINQILTSTVISLGGIFITLLGLPVYYYMKKR"
     gene            12513..13688
                     /locus_tag="KOU88_003230"
     CDS             12513..13688
                     /locus_tag="KOU88_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBK3213084.1"
                     /translation="MLGLYVHIPFCVKKCKYCDFNSYKMDIDSKKRYIEDLKIEMELY
                     SNKLYKDNKYKNKECCSLNKNDKITSIFVGGGTPSILTSDEIREVFISIKEMFDIDEN
                     AEITIECNPGTLTLEKLKTMKEIGINRLSIGLQAIQEKHLNFIGRIHTYEEFEKNYKD
                     ALSVGFKNINVDLMYSLPNQTLCDWKETLEKVVHLNPTHISAYSLILEEGTELYNMYE
                     SNKFELIDENVDIEMYEYTINYLKSKGYNQYEISNYSKEGYNCEHNILYWECEHYIGI
                     GAGASGYINENRYNNVESLEDYHLSLVKREKPIQENEILSEKDMIEEKIFMGLRMNKG
                     IKFEDFKKKFGIDFREKYNKQIEMLLARKLINQSFEGIQLTQKGREISNSVFIEFME"
     gene            13791..14810
                     /gene="hrcA"
                     /locus_tag="KOU88_003231"
     CDS             13791..14810
                     /gene="hrcA"
                     /locus_tag="KOU88_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HBK3213085.1"
                     /translation="MELNERKLNILKAIVKDYIETAEAIGSRTISKRHDLGVSAATIR
                     NEMADLEELGYLIQPHTSAGRVPSEKGYKLYVNSLMSKSELDDNDKILIEQCMNHNIN
                     HIKELIHETSKLLSQLTNYTTVAVTKSLINQSVIKHIQLVAMNDNNILLIVVTDKGDL
                     KKANLTTNVYLDQSKLNLISDNLTRKLLGKSITDLDDNLIAFIKYEISEYSGLIDELL
                     NALNSNMKEEDFSLSLNGATNIFSYPEFNDVLKAKSFLNMLEKKETIADIIKSKGIQK
                     DNLNIIIGSDNDCELAQDCSIVTATYNVDRDLVGRISFIGPTRMDYARIYSIINYMSL
                     LINRK"
     gene            14840..15460
                     /gene="grpE"
                     /locus_tag="KOU88_003232"
     CDS             14840..15460
                     /gene="grpE"
                     /locus_tag="KOU88_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBK3213086.1"
                     /translation="MDKKNEQQEVREENDTSINQESETQVELEEEVVNEECETSSEKT
                     DEKEVDDENVTDINSKLAEKKLQDELDELNDKYQRLQAEYANYRRRTQQEKETIGVFA
                     NEKIITELIPVIDSMERALDACEDKEDTMYKGISLVHKQLIDTLVKFGVEEIEAESKE
                     FDPNLHLAVMQESVDGVEANQIVMVLQKGYKLGTKVVRPSMVKVSC"
     gene            15552..17399
                     /gene="dnaK"
                     /locus_tag="KOU88_003233"
     CDS             15552..17399
                     /gene="dnaK"
                     /locus_tag="KOU88_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBK3213087.1"
                     /translation="MGKIIGIDLGTTNSCVAVLEGGEAQIIANSEGMRTTPSVVAFTK
                     DGERIVGEPAKRQAVTNADKTITSIKTHMGTDYKVNIDGKSYTPQEISAIILQKLKSD
                     AESYLGQTVTEAVITVPAYFTDAQRQATKDAGRIAGLDVKRIINEPTAAALAYGMDKL
                     DQEKKILVFDLGGGTFDVSILEIGDGTFEVLATAGNNRLGGDDFDQIVIDYLAEEFKK
                     AEGVDLRNDKMALQRLKEAAEKAKKELSSTMSSNINLPFITATAEGPKHLNIDLSRAK
                     FEELTRGLVEKTMEPTKTALQDAGLSTGDIDDVLLVGGSTRIPAVQEAVKKFIGKEPH
                     KGINPDECVAAGASIQAGVLAGDVKDLLLLDVTPLSLGIETMGNVMTKIIERNTTIPT
                     KKSQIFSTAADNQTAVDIHVLQGERSMAYDNTTLGRFQLTDIPPAQRGIPQIEVTFDI
                     DANGIVNVSAKDLGTGKEQKITITSNTNLSEAEIEQKIKEAEMNAEADKQKKEKIEAF
                     NQAESTIYQTEKTLNELGDKISSGEKEDIEKAIADLKAVKDNQDATAEELKKATDEVM
                     TKFQKVSQEMYQKAAQEQQAAQGAEQAQDNGPKDDNVVDADFKEVDEDK"
     gene            17610..18764
                     /gene="dnaJ"
                     /locus_tag="KOU88_003234"
     CDS             17610..18764
                     /gene="dnaJ"
                     /locus_tag="KOU88_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBK3213088.1"
                     /translation="MSTKRDYYEVLGISKGAEAQEIKKAYRKLAMKYHPDRNPGDKEA
                     EEKFKEINEAYEVLSDDTKRKTYDQFGHDGLNGQGGFGGQGGFGGQGFGGFEDMFGDI
                     FGDMFGGSFGGGRARRRGPQRGADIRQSVTISFEEAAFGKKMSIKVNRSEECEECNGT
                     GAKPGTSKKTCSTCNGTGQVRTVQRTPFGNIASSRPCSACNGTGEVIESPCSKCHGTG
                     NTRKVKTIEVDIPAGIDDGQMIKLSGQGEVGEKGAPRGDLYIVVNVKSHPLFTRDGND
                     IYFEMPITFVQATLGDEIEVPTLDGKVKYSVPEGTQTGTVFRLKEKGIPRIRGNSRGD
                     QYVKVVVEIPKKLNDKQKELLREFAKECGSNVHEKKKTFGQKIEDMFKKK"
     gene            19730..20665
                     /locus_tag="KOU88_003235"
     CDS             19730..20665
                     /locus_tag="KOU88_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK3213089.1"
                     /translation="MYYIGVDIGGTGIQAGVVDNYGKIIFRSECKTVIEKGFEGILND
                     IKIMIYKLLEDNKLTMSDIKSIGFGVPGFINKEGLVTCVNLKWNKKAFNKELKRRFPD
                     VEIHGENDATVAALGEAKFGSMKGANVGVLYTLGTGVGGGIVINQKVFSGAHGLGSEI
                     GHQIIGENYFNCNCGNNGCVETFCSATAIIKYSQKLIEEGEKSRILDLAEGNLENVNA
                     KMVFDAYRENDLVAIKVINRFKEYLAKTFANTINSLDPEIISIGGGISKSSDIILDGI
                     EGLVRKFVLYKTEDIATITCATLGSDAGIIGAAFL"
     gene            20701..22074
                     /locus_tag="KOU88_003236"
     CDS             20701..22074
                     /locus_tag="KOU88_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3213090.1"
                     /translation="MGKTNARRTLFLIAIGSGTMLNPLNSSMISLALHSIQNDFHISF
                     TTVSWIVSAFYLASAIAQPVSGKIGDLIGRKVLFLSGLMLVILSASIVPLVQSFFILI
                     FIRVIQAIGTSTLYPSGVALIQNNIKERQSSALAVLTIFASTTAGLGPTLGGLLLDLG
                     GWHAIFLVNIPVVLVSICLGYFLFPKEVKEKKSIKETLKNVLSRLDIIGILLFSIAMI
                     FILLFLLSMKESFNLEQLVFGIILMCLFIWHELRTKLPFIDIKLFVSNPKLSKVYLQF
                     IILNFFNYILFFGLPSYFQDALHYSAKSTGLFMLFMSGIGIFISPLTGKWIDKSGTRF
                     PLVTSSIFMFISAVLLSVVFIHIPVIGKGIILSLAGISYGVGNVALQSSMFEESPRDS
                     IGTASGLFQTSRYLGSILATVLLGMVFEVNITSEQFQILGYVMVVLGTISFLLNFILK
                     KELRKVE"
     gene            complement(22262..23029)
                     /locus_tag="KOU88_003237"
     CDS             complement(22262..23029)
                     /locus_tag="KOU88_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213091.1"
                     /translation="MEELKDFLERQLNKKINIYPYENQKLDASSHLVTFNNAIYVIDF
                     LDKNNLDNLKGNFYLIYQSHIDFEYLKNIFYNLFEDINIIQHNGFFIVNSKYNLDINV
                     TTQNIIETETYQSTYIFYLGKLDSKADFDFRLQLCSDLLPHIIKDNAENKFLNLFDLI
                     RYKTLDLINEDNILNKLIDFNKIKSIDEELLYTGIKFINNDLNISKTSTSMFLHRNTL
                     VYRLEKINEMLGFDLKNFENAMIFYLSVKSYFLYKKI"
     gene            complement(23059..24168)
                     /gene="ugpC"
                     /locus_tag="KOU88_003238"
     CDS             complement(23059..24168)
                     /gene="ugpC"
                     /locus_tag="KOU88_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003242648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBK3213092.1"
                     /translation="MSEVILKNISKLYSNGFNAVKNINIDIKDKEFIVLVGPSGCGKS
                     TTLRMIAGLEEISEGELYIGDKLVNDIEPKDRDIAMVFQNYALYPHLSVYENMAFALK
                     LRKLPKDEIDKKVKEAAKILDLLPLLNKKPKTLSGGQRQRVALGRAIVRNPKVFLMDE
                     PLSNLDAKLRTAMRTEITKLHQQLGTTFIYVTHDQVEAMTMADRIVVMKDGVVQQIAT
                     PQDVYDYPANIFVAGFIGAPQMNFIDVILIEENDEIYAQNEHIKLKLNKEKHYDLIKD
                     NYINNEVVIGIRPEDIHVEDTFIKSNPDTCFKSRIEIKELMGAETYAHLKLGENTITI
                     RFDSKNRINVGDDLTLSVDNSRVHIFDKETTLAIR"
     gene            24627..24803
                     /locus_tag="KOU88_003239"
     CDS             24627..24803
                     /locus_tag="KOU88_003239"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213093.1"
                     /translation="MNLNRIKEIIKKGLKRFMKVVVNLFCNKLFHRMLYIISISVVVK
                     ITMDINLYISILKY"
     gene            24904..25641
                     /gene="cas6"
                     /locus_tag="KOU88_003240"
     CDS             24904..25641
                     /gene="cas6"
                     /locus_tag="KOU88_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated endoribonuclease Cas6"
                     /protein_id="HBK3213094.1"
                     /translation="MSRISIFMESCNGKFPNENSMLSVSFIKNILNAENKDFAKNIFN
                     YGEERKNNKQIKDINTAIYIPNLIRSKNELLVDGDIIFNISFYNYSMFSKLYNGILKV
                     KELEYKGYRFKIKNIKIHKEHEIKENGVIFKTMSPIIVKNKEGKYLDVEDSNYIECLN
                     YIANLTLESIRGSGLRKPLEFIPLNFKKRVLKEKIRGFKEREFYYINAYAGTFFLKGN
                     MEDLNALYKMGIGYRRTENAGMVDILK"
     gene            25646..27121
                     /locus_tag="KOU88_003241"
     CDS             25646..27121
                     /locus_tag="KOU88_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213095.1"
                     /translation="MREIKAKFYRSGDIVRDIGIVYFCELLMDLKNELEKNDYKLKFT
                     CELNRNYLSLESAEYIDPKYISDYILENQLFKVFKNGKKETLEKIFSNIDNLTYVNFI
                     EELDKSSATEKQKEGIKKDFKNRRFPYVRNSGKYGLNTSLENMETNVKRIVDIVIKSN
                     IEIDEIDKLDLKQYEEKDSVCNVCNINKTTKLDIDLRERKDSKYNFLFRGAEKSGFKR
                     SGQVESNICFECEFFNLMCLLYINLKRPMVFAYTNDLRELAFLNHKIMLKRKMYSDKS
                     FYKKLLHEKISSIRLYRIDIDTNKGIILKFDSIIEYKELLKKIELIDIIDNYNFSREP
                     MNTRNLGKKMINNGNLSNLKELLLDNISVLRQLTGTSREMDFVSSSYNIGLYIKLCWI
                     VDGREEYKMKNYIESNLIYSRVGKDLFNKMTDESRRKNFSMKVIQLLKSNDRTQLFQT
                     IMHVLVSNGILIGEGFVEGLMQSSELELNTNVGLFIQEIMK"
     gene            27141..>28006
                     /gene="cas7i"
                     /locus_tag="KOU88_003242"
     CDS             27141..>28006
                     /gene="cas7i"
                     /locus_tag="KOU88_003242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-B CRISPR-associated protein
                     Cas7/Cst2/DevR"
                     /protein_id="HBK3213096.1"
                     /translation="MNEKRVKGVTLTILTESPVPLSYDQGYGNYTPIKKEQYRDKVHA
                     KTSIATITYDLRRILHQEYGWNLSNIVFGKKGNIYPSIKKNVGCVDENGLETDVFGYL
                     IPLKEKGSISKASPLRIIPFRSLNSYRGSTQLITNRGFLSSEFGRKYYDEREENEVLR
                     DENFPTTQALAIEETLSDYYVYTITLELDRIGVVEVEEDGKLLLPEERKFMSKELREK
                     AVKDILDAITVFTRNIKHSSVLLKPLAVMGGAFDKVVPFFWDDVDYNADSGEINLEGV
                     IETIESYSLKES"
BASE COUNT        11131 a         2966 c         4797 g         9112 t
ORIGIN      
        1 cattacaaat aacacaaaaa acgacgaaga acttaatgat aagataataa ctatacaagg
       61 agttgtcaaa ggaaaaattg aaaagaaaag atacaatcag tacaaggtag gggtttttct
      121 aataaatgat tatacaaaaa ataaaaattt gaagattggt cagaaagtta atattacagg
      181 taaattcaaa agtttagata aaatgaagta tgatgatttt gattatggaa ggtatataaa
      241 aagtactgga tataaaggta tagtgtatat aaataactat aaaattattg ataaaaataa
      301 actttactct ttaatagggg aaataaagtt ttatattagt aaaacttata ggtacttata
      361 taagaaaaac tcagatttta taaattctat actattagca gaagttgaaa atttgactga
      421 ggaacaaaaa gaaattttta ctagaactgg aactagtcat gtaatatcta tatcaggtct
      481 tcatacagga atattatgtg taattatatc ctttctatta agaggtataa ataaattgta
      541 taaattatta atactgtcga tttttataac tttatattgt ataatggtag gtgcgtctcc
      601 atccataatt aggtctatag catttgttat gattttttat ttatcaatat ttattgatag
      661 aaagaaagat ggaatatcgg cattgtctct aattgggata attttaatta tgaataaccc
      721 ctatgttata tataatgtaa gttttcaatt gtctttttta gctacacttt ctatattaat
      781 attctataat aaaataaata gtattataaa attaagtatg gtatcattga caatatcatc
      841 aaatatatta actttaccta taatttatta tgcatttaaa ggtataccat tgctttcaat
      901 tataggaaat ttaattatag taccatttgt gggagtaata atgtatttaa gtattgcaag
      961 tttaatcgta tttaaagtaa gtgtagtaat agctaaaatt atatcttttt ttaatagtac
     1021 attgatagaa agcatatttt ttttactaga aaaaatcagc aatttaagtt ttgcatacat
     1081 taatatagaa agtcctaaat tttatattgt tgttatttat tacataggag tgttttttta
     1141 catattttac atagaaggaa aagagataaa ggagcaagag aatgaattac aaggatatta
     1201 taaggaatgt aaaagagaaa aactttgaaa aaatgtatct tttttatgga agagagtatt
     1261 atttaattga gaatgcaata aaagcattta aagatagtct aaacgaggga atgcttgatt
     1321 ttaatttaga tataatagat gggaaggaaa tagtcttaaa tcagcttata agctctatag
     1381 aaacacttcc atttatggat gataggaaga tagtaataat aaaagacttt gaactattaa
     1441 aaggaaagaa aaagaatttt acagatagtg atgagaaata cttaatagag catttagaca
     1501 atattccaga caccacaact atagtttttg ttgtatatgg agatgtagac aaaagaaaat
     1561 cattagttaa gaaaatagga aacaatggaa ttgtttttga ttgtgataag ctttctgata
     1621 tggatttgtt taaatggata aaaaaatctt ttgctttaaa tgatgttata atagataatt
     1681 ctcaaatcat gtattttatt gaacaagaag gatacagaga taagagtagt gaaaagacat
     1741 tatctgattt agaaaatgaa ataaataaaa taagttcatt tgttggtaaa gggaataatg
     1801 taaccaatga tgtaattgat aaattatctc aaaaaaaagt tgagaatgat atattcaaat
     1861 taatcgatta tattggagaa caaaatgctt ctaatgcaat gaaaatatta aatgatatga
     1921 tacaagaagg cgaatctgta ttaggtatat tttctatgat agcaagacaa tttaaaataa
     1981 ttatgcaagt aagacagtta caacttgatg gatattcaac aaaacttata gctgataaat
     2041 taaaaatgca tcaatttgtt gtaggaaaag cattaaagca aactaaaaat ttttctgatg
     2101 atataattgt ggaaatatta aactatatat tagaaagtga ttacaaaata aagacaggtc
     2161 ttataagaga tactttagca gttgaaatgt tggttagtag atactgtaaa agagaagcaa
     2221 tttaaaaaat ctatatatta ataaaaaata aatagcaaga tatgttatag ttcagagtag
     2281 atgtaagcta aattaagttt gatatacaat caactataat atgtctaact atttattttt
     2341 tattgtataa atttacaaaa taaaaaaccc ctacataggg gttattatat ataagaaata
     2401 taaactggta attaagcgtt cataccgttt aatttttgag ctaatttagc tacttttcta
     2461 gctgcagcat tcttatgtat agttccttta gaagctactt ggtatattct tttttgagcg
     2521 tattggaact tagcaacagc atcctctctg tttccagctg caacagcatc ttcgaatctt
     2581 cttattgcag tttttatttg agattttcta actctattta aagcagtttt cttttcgata
     2641 acacttattc ttttcttagc tgattttata tttgccaccg tgttcacctc cctgtatttt
     2701 tttatcatat tcatcgtcaa catattagat tttaacagaa ataaatctaa aaatcaagga
     2761 ttattattta tatattttaa taatgttttt tattttgatt ttttagactg taaattgtgt
     2821 ataaataatt tgcaatatct tgtttttaaa ttggtatatt ttgtgtttta aatattttga
     2881 catatataaa ttaatatttt atttttgtaa caaatatttt gagataatac aaactattaa
     2941 catacatttt gatagtattt ccaataatta taagataata caagaaatta ctcattttta
     3001 taaatttaat gaaaaaatat aaaaatataa atttatatgc ttaattaaga taatttttcc
     3061 aataatcaag ataatttttt tcattagtat gtatgataga tgcatcaaac aatataacta
     3121 atatgttgga aggttatatg taattaatct cagtgtttat atagaatagc atttgtagca
     3181 tttattatag ttgtaattac tatttatatc atagccttga atagtctaaa aaaatagact
     3241 ataatatttt tatagactaa agaaagggct gataagatgg acatagcaaa actaatttta
     3301 aatcctgcaa ggcttcgtat tttacaatat attcgacttc atagcagtgt tcgcacatct
     3361 gatattgtaa agtatttaaa tgatattcct cgtgcaacag tttatcacca tgtaaaaatt
     3421 ttagaagaga acaatatgat tgaagtaatt aaagaaaatc gtgtgcgtgg tactattgaa
     3481 aaggtttatg cactaaagga atatacaaca tctatggaag gagagacctt cgttgcactt
     3541 tctacagcat tttatgtagg tctgatgcag gaaatgaatg aatactttag cagaaaagag
     3601 caagaccata aaaaggataa tgtatttttc tcttcagcat tactatatat gagtgataat
     3661 gaatatgaaa atcttcttaa aagtatagct gatttattga aaccatatat agaacaaaaa
     3721 cctaaatcaa atctaaaact tagaaaactt tcaattatat cttctccacc tgtagctgat
     3781 aatgataaaa caaaataaca tgcaacccat ttttataaaa ggaggttata tatgaaattt
     3841 catgagtttg gaaataaaaa cagaccacat attatgttga ttcatggggg agggaatgca
     3901 tggtggaact atttgcgaca agcagaagtt ttgtctaaca aatatcatgt gatacttcct
     3961 acattggatg gtcatggaga agaatatgaa acaacataca tttctacaga ggatacagca
     4021 gataagttga tatcatatat agatgaaaat tgcagtggac atcttttcgc tttgtgtggg
     4081 gtatcacttg gtggtcaaat tgtcatggaa cttttatctc gaaaacctaa tattactaaa
     4141 aaagcaatta ttgatggtag tatttgctac ccaagacctc ttatggcaag gttttgtatt
     4201 gctggtattc gattttttgg aggacttttg tttagtgaga aggcttgtcg ctttcaaatt
     4261 gctatgatgc caaaattgtt acctgaaaat atgcaatatc cagatgaaat aaaagcatat
     4321 tatatgacag atatgccaca tgtaagaaaa gaaacattct ataatatgta tcgcacttac
     4381 atgatgaact atacacttaa agagaatgtt aaaaaaacca cagcacaagt aatgtactgg
     4441 tatggagaaa aagaaatgaa atgtgttaaa aaatctgcaa aaatgtttca gtcttatgtg
     4501 ccctcttgtg agatttatga agctaagagc tataatcatg ggtatttatc actttatctt
     4561 ccaaatgaat ggttggaaat tgcagaacca tttttccaaa aggaataaag gtgttaggtg
     4621 attattgtat aattattgct gtttttttat atagtaaata aattaggtat aaatataaaa
     4681 aattatttta gttaatatat tagtgaaagc ttaataggaa aattataaat agattaaagg
     4741 tagcgcctat ataaatagtt gctacctttt tctgtttgta aataaatgat agataagaag
     4801 gtttactgac aaatcactga ctaaacccaa ttttcttaca ttgaaagcct taattttact
     4861 tgttttaaat aaatttacaa tttcttgtta taaaatacta aattttgtta acaattataa
     4921 ttagcattta atttatactg gaggtttata tgattagtgt aagaacagat ttagctttag
     4981 aagctagtga aatgtgtgaa aagtctcaag aaggaagtag tattcctggt gtaaaaatag
     5041 aaactaaaga attagaaaat tgcattgtaa ctaaagttga agtaatagac aggcaaggcg
     5101 cagagataat gaataaagat ataggaaagt atataactct ggaaagtaat cttatgaagt
     5161 ttgatgatga tgagtcaaga gaagaaatga taagttattt aaaagaggag ttagtagata
     5221 tatttggcca agacaaaaat aaaaaaaccc tggtaattgg tcttggaaat agaaatatta
     5281 cttctgatgc gttaggacca aagagtgtat caaaaacact tgtaactaga catcttttta
     5341 aaaattataa taaagactat gatgatgatt tcactgaggt atcagcttta agcccaggag
     5401 ttatgggtgt tactggaata gaaactagtg aaatagtaaa atcattggtt gagaaggtta
     5461 agccagatag agtagtagca atagatgcat tggcttcaag aaaaatggag agagtaaact
     5521 ctactataca gatatcaaca gcaggaatat cacctggtgg aggtgttggc aatactagaa
     5581 aatctctaac taaagaaact ttaggcgtgg atgttattgc aataggcgtt ccaacggtgg
     5641 ttgatgcagc aactcttaca atagatgtct tagatatggc aatagacaat ttaatagctc
     5701 aatcagaaga aacagaaagt ttttatgaaa tgttgaaaaa acttaaagaa gaagaaaaat
     5761 atcatctaat aaaagattcg ttagacccat atgacaagaa cttaatagta acaccaaagg
     5821 atatagatga tacaatcgaa aatctatcta taataataag tgaaggctta aataggtctt
     5881 tacatccagg tagattggta taaaataagg aggagcaatt atgtttaaaa aatgcattaa
     5941 agtagtaacc ttgactttta tattagtatg cattttacca ggaaaatcat tagctttgaa
     6001 tcaagatgat tttttaaagt ttttagtaaa ttcatcttat ccagaagcta aagtcgaagg
     6061 aaatgataca gaaaataaaa agaataataa aaataaagaa acaagtaagg aaaataagga
     6121 agaaagtaaa gaagaaaaca ctaaatctaa agatgcaagt aaagttgata ataaaaaaga
     6181 gagtgaaaaa gaatatataa aactttatgt tggtaaagaa aatgttccag atattgagtc
     6241 aaaaaattca gacacaactg aaactaacac aacatctagt tcagattata aggatgattt
     6301 aagagtaacc aaagaaaatc caagaatttt gatatatcat actcatggat gtgagactta
     6361 ttcaaattca cctgatggaa attatcattc aagagataag aaaaattcag taatggaagt
     6421 aggaagtgca ttaactagtg ctttagatag caaaggatgg ggtgtagttc atactactaa
     6481 ataccatgac tatccatctt ataataactc ttatgcaagt agcttaaaaa caatacaaag
     6541 tatattacct aaatataact cagtggatat agcgatagac ttacatagag atgctaggga
     6601 tttaactaat ccagccacta aggaaaaaga ccatttaaaa tatacaacta tgataaatgg
     6661 agagagagta tcaaagttct tctttgttgt aggaggtaaa aatacaaata gaaaacaact
     6721 tagagcttta gcagaagata taactgcttt tgctgagaaa aagtatcctg gtctagtatc
     6781 tccaatagta gaaaaagact atgctagatt caatcagttt gcagttaaga atcatatgtt
     6841 agtagaaata gggaataacg caacaagtgt agaagaatct aaggctacta caaagtattt
     6901 agccgagatt ttggatgaat attttaaaca aaaaaattag agctttaagt tataattagg
     6961 agcatgctaa atgagccgat tagaaaaaaa tatagaaagt aaaagtaaac taagaaaata
     7021 caagtatatt atgagaatct tatttttgat tactatgatt atatgtacat cagtttgtgt
     7081 atttatagtg gacagtaatg caaaaagtat gctaggaatg aaacaatatg attttccaag
     7141 tattaaattt gatataacaa aatttgattt tgacatacca aattttgata tacatgaaat
     7201 cataaaaaaa tttaataagt agtaataagt gaataaggtt tattgattaa aataagcctt
     7261 attttagtta tatattttta atgtataaaa taaaaattca ttaactgtat tttataggat
     7321 ttactttaag tttatgatat tatataatat ttagtgttag acttgataat ccacatataa
     7381 tgtggataat tttgtttagt gccaattagt ttatattcaa aaattttaaa tttggtatat
     7441 aaagagtttt tagataatgt aaaataataa ctataagaat aatcaagagg agggaatttt
     7501 aaggtggaca ataaacaaag tagaactaga aattttagta taattgcaca tatagaccat
     7561 ggaaagtcta ccttagctga tagattaata caacaaactg ggcttgttag tgaaagagac
     7621 atgaaaagtc aattacttga caatatggac cttgaaagag aaagaggaat cactataaag
     7681 cttcaaaaca taagattaat gtataaagcg aaggatggaa atgaatatta tttaaatctt
     7741 atagatacac ctggacatgt agactttaac tatgaggtat caagaagttt agctgcatgt
     7801 gaaggagcac tattagtagt tgatgcagct caaggtgttg aggcacaaac tttagccaat
     7861 gtttatcttg ctatagacca agatttagaa atattaccaa taataaataa aatagattta
     7921 ccaagtgcaa gaccagagga agtaaaaaat gaaatagaag atttaatagg gcttgattca
     7981 agtgaagctc ctcttatttc agctaaaact ggtttaaaca tagaagatgt tttagaagat
     8041 attgtaaaaa atgttcctcc acctaaagga gataatgaag ctccattaaa ggcattaata
     8101 ttcgattctt actatgatgc ttacaaaggt gttgtagctt atgttagagt atttgaagga
     8161 actgttaaaa agggtatgac aataaaaatg atgaatacca ataaaaagtt tgaggtaact
     8221 gaagttggtg ttatggctcc aggtcaaact gaacttagtg aattatcagc aggtgatgtt
     8281 ggttatattg ctgctagtat aaaagatata agaagttgtc gtgttggtga tacaataaca
     8341 gattcaaata atcctacaga agaaccttta ccaggataca aaaaagctac tccaatggta
     8401 tattgtggta tatatccagg agaaggagaa aagtatgaga atgttagaga tgctcttgaa
     8461 aagcttcaag taaatgatgc tgcacttgaa tatgaagctg agacttcagc agcactagga
     8521 tttggtttta gatgtggttt cttaggtctt ttacatatgg agataatgca agaaagactt
     8581 gagagagaat ttaaccttga tataattact acagctccat ctgttatata tagagttaca
     8641 aaaatggatg gagaggttgt aatgatacaa aatcctgcaa acttaccaga accatctgag
     8701 ataaagatga tagaagagcc tatagtaaaa ggagatataa tagttcctaa agactatgtg
     8761 ggtgttgtta tggagctttg ccaggaaaga cgtggaaata tgttaaatat ggaatatata
     8821 gatgatagaa gagtaatgct tcactatgac cttcctctca atgaagttgt ttacgatttc
     8881 tttgatgctt taaaatcaag aactagaggt tatggttctc ttgattatga ggttaaaggt
     8941 tatgtagcat ctacacttgt aaaacttgat atattaatca ataaagagca agtggatgca
     9001 cttagtttta ttgtccatga gacacgtgct ttccctagag gaaaggcaat gtgtgagaaa
     9061 ttaaaaggag aaattccaag acatcagttt gctataccaa tacaagctgc tgttggtaat
     9121 aaggttattg caagagaaac aataagtgct ctaagaaaag atgttcttgc taaatgttat
     9181 ggtggagata tatctcgtaa gaagaaactt cttgaaaaac aaaaagaagg taagaagcgt
     9241 atgagacaaa ttggttctgt tgaagttcct caaaaagcat ttatgtctgt gcttaaatta
     9301 gatgagtaaa tccttataaa tttagataaa gatatttaaa agctagagtg attttagaat
     9361 tatttctaaa ttagtctagc ttttttatgg tatattttaa gtaaactcat agagaatata
     9421 agtaagaata ttaaagaaga ataaaaaggt gatatttatg attaatatag aaattcctaa
     9481 aaaagtagac tatataatta aagaattaga aaagaatggt tatgaagctt atatagttgg
     9541 aggatgtgtt agagattgtt tattagaaag agttccaaac gattgggata taacaactag
     9601 tgctagacca gaagtggtag tagaattatt tgaaaaaaca attccaactg gtatacaaca
     9661 tgggactgta acagttatga ttgaacatga accatttgaa gtgacaactt atagaattga
     9721 tggaaattat agtgatggta gacatccaga ttcaatagaa tttacaaata acatagttaa
     9781 ggacttgtca agaagagatt ttactatcaa ttcaattgca tacaattcaa agacaggatt
     9841 agtcgaccca tttaatggct atgaagatat acaaaataag tatatacatt gtgttggaaa
     9901 tccagtagat agatttgaag aagatgcact tagaatgctt agagcagtta gattttcagc
     9961 acaactcaat tttaaaatag ctgaaggtac taagcaaagt attcataaaa aagcagattt
    10021 gataaaaaat gtttctattg aaagaatcca gacagagttt aataaaatat tagtatctga
    10081 ttcatctaaa ttaaacttat taaaatcaac aggtttgttg aaatttataa ttcctgaaat
    10141 atgtgaatta gaagatgtta ctcaacacaa tccatatcac atctatgatg tacaaaaaca
    10201 tactttaata gctacagaag caattgaaga tgaactgtat ttaaaactta caatgttgtt
    10261 tcatgattta ggtaaaaaag taactaaaac aactgataaa aatggtgttg accattttta
    10321 tactcatagt agagaatctg taaagattgc aaagaagatt ttgaaaagac ttaagtatga
    10381 taattatact attaataaag ttttaatatt aatacaatat catgattata gaatagaacc
    10441 taaaaggaag ataattaaaa agttattaaa taaacttgaa gatgttggat tatttgaaga
    10501 tttaataaaa gttaattggg ctgatacact tgcaaaaaat ccaaagtatg caaaacaaaa
    10561 gatattaaat cttattgagt gtgaaaaaga atttaaacat ataataaatc aaaaggagtg
    10621 ctttaatctt aaagatttag ctattaatgg aaaagatttg atatctatag gtataaaacc
    10681 aggtaaagat ataggatata ttttaaataa gatgcttgaa atagtcataa ataatccaga
    10741 gttaaatgaa aaagaaatac taaaagaaaa agcattaaat atatatacat tttagattca
    10801 aatataaaaa atttaattac tttaaaaaac atagaataaa atacttattt agataaaata
    10861 aataattttt agagaatatt ttagaagtta cgattgtatg atttttaaat gcataggcat
    10921 ttactctagg actatagact aatataaaaa aaaactttgg gaatactaaa accataaatt
    10981 tataaaatta atattttata tactgtaaaa cagtgaggag ggacagtatg catactcaac
    11041 tacaaaagac tattggtctt tcagcagctc tttctactgt tgtaggtatg gttataggtt
    11101 cgggagtttt ttttaagcca caagcaatat acactacaac taatggagct ccaggtctag
    11161 gtattatagc gtggctttta ggtggtttta taacaataac tgctgggctt acagctacag
    11221 aaatttcagc tgctatacca aaaactggtg gtatgatgat ttatatcgaa gaaatatatg
    11281 gagaaaagtt aggtttttta actggatgga tgcaaactgt attatttttc ccaggtacat
    11341 cagcggcatt aggagtaata tttgctcaac aagcatctga acttttagga atgagcccaa
    11401 ataatatggc aaatgtactt cctatagcaa ttggagttat actattttta gcgttattaa
    11461 atataatagg ttcatcctta ggaggaaaag ttcagacagt agccactatt ggaaagatga
    11521 tacctttaat tttaataata gtctttggat ttattaaagg tcaaagtagt gaagtattaa
    11581 atccatttgt aggagatggt gtaaatgcat caaatgcact tggacaagta ttaatagcta
    11641 ctttgtttgc atatgatggt tggataaatg ttggagctat atcaggagaa atgaagtctc
    11701 cagagaaaga tttaccaaga gcaatagttg gtggtttatc attagttatg gcagtttata
    11761 ttataataaa tatagcttat ctttgggtag taccagcaag tgaattagca acagttactt
    11821 ccccagctac attagtagca acaagattgt ttggaaatat aggtggaaaa gtaataactg
    11881 tgggtatatt aatatcagta tttgggacat tgaatggata tttattaaca ggttcaagga
    11941 taccttatac attagctgaa atgggaactt taccagcatc taaaactctt ttaaaagtaa
    12001 attctggagg ttctcctgta aattcaatac tacttataac tgtgttagcc tgtgtatatg
    12061 cattatctgg tcaatttaat cttttgacag acttaacaat attttcaata tgggtatttt
    12121 atgtattgac ttttataggt gttatgaggc ttagaagaca aaagccagat ttacacagac
    12181 catataaagt ccctttatat ccaataatac caattatagc tatattaggt ggactgtttg
    12241 taataataaa tcaaatattg acttcaacag tcatatcttt aggcggaata tttataacac
    12301 tattaggttt accagtttat tattatatga aaaaaagata actacttaat ttaagttaga
    12361 taaatttggg taaaggtgaa aattaacttt tatccaaatt ttttatactg ttatacaata
    12421 taagtattat atattgcttg atgtgctatt ttgtttgatt tataatttag taattgatgt
    12481 tttaagataa tttaagaaat gaggagtgaa agatgctagg actttatgta catattccat
    12541 tttgtgtgaa aaaatgtaag tattgtgatt ttaattctta taaaatggac atagattcaa
    12601 aaaaaagata tatagaagac ttaaaaatag aaatggaatt atatagtaat aaattatata
    12661 aagataataa atataaaaat aaagaatgct gtagtctaaa taaaaatgac aaaataacga
    12721 gtatatttgt agggggaggt acacctagta tactaacctc tgatgaaata agagaagtat
    12781 ttataagtat aaaagaaatg tttgatatag atgagaatgc agaaataact atagagtgta
    12841 atcctgggac attaacatta gaaaaattaa aaactatgaa agagattggc ataaatagac
    12901 ttagtatagg gctacaagct attcaagaaa agcatttgaa ctttatagga agaatacata
    12961 cttatgaaga atttgagaaa aactataaag atgcattaag tgtaggtttt aaaaatatta
    13021 atgtagattt aatgtacagt cttccaaatc aaactctatg tgattggaag gaaactcttg
    13081 aaaaagttgt acacttaaat ccaacacata tatcagctta ttcccttata ctagaagaag
    13141 gaactgaact atacaatatg tatgaaagta ataaatttga acttatagat gaaaatgtag
    13201 atatagaaat gtatgagtat acaataaact acttaaagtc aaaaggatat aatcaatatg
    13261 aaatatcaaa ctactcaaaa gaaggctata attgtgagca taatatttta tattgggaat
    13321 gtgaacatta tatagggatt ggagcaggag cttctggcta tattaatgag aacagataca
    13381 ataatgtaga atctttagaa gactatcatt taagtttggt aaaaagagaa aaaccaatac
    13441 aagaaaatga aattctttct gagaaagata tgatagaaga aaagatattt atggggctta
    13501 gaatgaataa aggcataaaa tttgaagatt ttaaaaaaaa atttggaata gattttagag
    13561 agaagtataa taagcaaata gaaatgctat tagctagaaa gcttataaat cagagctttg
    13621 aaggtataca attaactcaa aaaggaagag aaatatctaa tagtgtattt atagaattta
    13681 tggaataatt tttaaggtgt tgacaaaata aatttataat ggtatataat atatataatc
    13741 tttttagcac tcgaacttag tgagtgctaa cagctaggag gtataataat atggaattaa
    13801 atgaaagaaa attaaatatc ctcaaagcta tagttaaaga ttatatagaa acagctgaag
    13861 ctataggttc tagaacaata tctaaaagac atgatttagg tgttagtgct gctaccataa
    13921 gaaatgaaat ggctgacctt gaagaattag ggtatttaat tcagcctcat acttctgcgg
    13981 gtagagttcc atctgaaaaa ggctataagt tatatgtaaa ctctcttatg agtaaaagcg
    14041 aattggatga taatgataag attcttattg aacaatgtat gaatcacaat ataaatcata
    14101 taaaagaatt gattcatgaa acttctaagc tattatcgca actaacaaac tatacaactg
    14161 tagcagttac taagagttta ataaatcaaa gtgttataaa gcacatacag ttggttgcta
    14221 tgaatgacaa taatatttta cttatagttg taacagataa aggggactta aaaaaagcta
    14281 accttacaac taatgtatat ttagatcaat ctaagttaaa tttgatttct gataatctta
    14341 caaggaagct cttaggtaaa agtataacag atttggatga taatctaatt gcttttatta
    14401 aatacgaaat aagtgagtat tctgggctta tagatgagct tttaaatgct ttgaactcaa
    14461 atatgaaaga agaagatttt tctctatcat taaatggagc tactaacata tttagttatc
    14521 cagaatttaa tgatgtatta aaagcaaagt catttttaaa tatgttggaa aaaaaggaaa
    14581 caatagctga cataattaaa tcaaagggaa tacaaaaaga caatctaaat ataataattg
    14641 gtagtgataa tgattgtgaa ctggcacagg attgtagtat agttacagca acttataatg
    14701 tagatagaga cttggttggg cgaataagct ttataggccc taccagaatg gattatgcta
    14761 gaatttactc tataataaat tatatgagtt tattaattaa tagaaagtaa agaaatttta
    14821 aattgcgagg tgtaaagtct tggataaaaa aaatgagcaa caggaagtaa gagaagaaaa
    14881 tgatacttct attaaccaag aatcggaaac tcaagtagag ttagaagagg aagttgttaa
    14941 tgaagaatgt gaaacatcaa gtgaaaaaac tgatgaaaaa gaagttgatg atgaaaatgt
    15001 aacagatata aattctaagt tagcagaaaa aaaattgcag gatgagttgg atgaattaaa
    15061 tgataaatat caaagacttc aagccgaata tgcaaactac agaagaagaa ctcaacaaga
    15121 gaaagagaca ataggcgtat ttgcaaatga aaaaataata actgaattga taccagttat
    15181 agatagtatg gaaagagcct tagatgcatg tgaagataag gaagatacta tgtataaggg
    15241 tataagcctt gtacataaac aattaataga cactttagta aaatttggag tagaagaaat
    15301 agaagcagaa tctaaggaat ttgaccctaa tctacatcta gcagttatgc aagaaagtgt
    15361 agatggagtt gaagcaaatc aaatagtaat ggtacttcaa aaaggatata agctaggaac
    15421 taaagttgta agaccttcaa tggttaaagt ttcttgctaa gtataaatta aaggttaaat
    15481 tatttaacct aatataaaat attaaaataa gtaaaactta attatataat tactcgagga
    15541 ggattttagt catgggaaaa ataataggaa tagatttagg aacaacaaat tcatgtgttg
    15601 cagtgttaga aggtggagaa gcacaaataa tagcaaatag tgaaggtatg agaactactc
    15661 catcagtagt agcatttaca aaagatggtg aaagaatagt tggagaacct gcaaaaagac
    15721 aagcagttac aaatgcagat aaaacaataa cttctataaa aactcatatg ggaactgatt
    15781 ataaagtaaa tatagatgga aaatcatata ctccacaaga aatatcagca ataatattac
    15841 aaaaattaaa atcagatgca gaaagttact taggacaaac agtaacagaa gcagttataa
    15901 cagtaccagc ttactttaca gatgctcaaa gacaagcaac taaagatgct ggtagaatag
    15961 cagggcttga tgttaagaga ataataaatg agccaacagc agcagctctt gcttatggta
    16021 tggataaatt agaccaagaa aagaaaatat tagtatttga cttaggtgga ggaacttttg
    16081 acgtatctat acttgaaata ggagatggaa cttttgaagt tttagctaca gctggtaaca
    16141 atagattagg tggagatgac tttgaccaaa tagtaataga ttatttagca gaggaattta
    16201 aaaaagctga aggtgtagat ttaagaaatg ataaaatggc tcttcaaaga ttaaaagaag
    16261 cagcagaaaa ggctaagaaa gaattatcat caacaatgag ttcaaacata aacttacctt
    16321 tcataactgc tacagcagaa ggaccaaaac acttaaatat agatttatca agagctaaat
    16381 ttgaagaatt aactagaggt ttagttgaaa aaactatgga accaactaag acagctttac
    16441 aagatgcagg actttctaca ggtgatatag atgatgtatt attagtaggt ggttctacaa
    16501 gaataccagc agtacaagaa gctgttaaga agtttatagg aaaagaacct cataaaggta
    16561 taaacccaga tgagtgtgtt gcagcaggtg cttctataca agctggagtt ttagcagggg
    16621 atgttaaaga cttattatta ctagatgtta ctccattatc tcttggtata gaaactatgg
    16681 gtaatgtaat gactaagata atagaaagaa atactacaat accaactaag aagtctcaaa
    16741 tattctcaac tgctgctgat aaccaaacag ctgttgatat acatgttctt caaggtgaaa
    16801 gaagtatggc ttatgacaat acaactttag gaagattcca attaacagat ataccaccag
    16861 cacaaagagg aatacctcaa atagaagtta cttttgatat agatgcaaat ggtatagtta
    16921 atgtttcagc taaagattta ggtacaggaa aagagcaaaa aataactata acatcaaaca
    16981 ctaatttatc agaagcagaa atagagcaaa agataaaaga agcagaaatg aatgcagaag
    17041 ctgacaaaca aaagaaagaa aaaatagaag cattcaatca agctgaatct actatatatc
    17101 aaactgaaaa aactttaaat gaacttggag ataaaataag ttcaggtgaa aaagaggata
    17161 tagaaaaagc tatagcagac ttaaaagctg taaaagataa tcaagatgct acagcagaag
    17221 aacttaagaa agctacagat gaagtaatga ctaagttcca aaaagtatct caagaaatgt
    17281 accaaaaagc agctcaagaa caacaagcgg cacaaggtgc agaacaagca caagacaatg
    17341 gacctaaaga tgacaatgta gtagatgctg actttaaaga agtagatgaa gataaataag
    17401 ctatataata tgtaacacta aatgataatt ggaacatata tgatttgtga aaatcatata
    17461 gatgttaaag atatatggac aatatacatc ataaagaata taatatatca tagattatat
    17521 aacttaaagt agaatataag aattaatgat agcttgtagt ttattattct acaagctatc
    17581 gttttgtaaa atgaaggtgg tgtcaatttt tgagtacaaa aagggattat tatgaagtct
    17641 taggtatcag taaaggtgca gaagctcaag agataaaaaa agcttataga aaattagcaa
    17701 tgaagtacca tccagataga aatcctggag ataaagaggc ggaagaaaaa tttaaagaga
    17761 taaatgaagc ttatgaagtt ctatctgatg atacaaagag aaaaacttat gaccagtttg
    17821 gacatgatgg gctaaatggt caaggcggtt ttggtggtca aggaggattt ggcggtcaag
    17881 gctttggggg ttttgaagat atgttcggag atatatttgg tgacatgttt ggaggaagct
    17941 tcggaggtgg aagagcaaga agaagagggc ctcaacgtgg tgcagatata agacagagtg
    18001 ttactatatc ttttgaagaa gctgcatttg gtaaaaagat gtctataaaa gtaaatagaa
    18061 gtgaagaatg tgaagaatgt aatggaactg gagcaaaacc aggaacatca aagaaaactt
    18121 gttcaacttg taatggaact ggtcaagtta gaactgttca aagaactcca tttggtaata
    18181 tagcaagttc aagaccatgt agtgcttgta atggaactgg agaagtgatt gaatctccat
    18241 gtagtaaatg tcatggaact ggaaatacaa gaaaagttaa gactatagaa gtagatatac
    18301 ctgctggtat agatgatggt caaatgataa aactttctgg tcaaggtgaa gtaggagaaa
    18361 aaggtgctcc aagaggagac ttatatattg tagttaatgt taagtcacat ccactattta
    18421 ctagagatgg aaatgatatt tattttgaaa tgccaattac atttgttcaa gcaactttag
    18481 gtgatgagat agaagtacct actttggatg gaaaagttaa atatagtgtg ccagagggga
    18541 cacaaactgg aactgtattt agacttaaag agaaaggaat ccctagaatt agaggtaatt
    18601 caagaggaga ccaatatgtt aaggttgtag ttgaaattcc taaaaaatta aacgataagc
    18661 aaaaagaact attgagagaa tttgcgaagg agtgtgggtc gaacgtccac gaaaagaaga
    18721 aaaccttcgg acaaaagata gaagatatgt ttaagaaaaa gtagttaaag tagccaatat
    18781 ataatcatat ttttaaaatc ttagttattt ataagattgt caaaggagat attatgattt
    18841 ttatattggc tatttttgta taaaaaataa atgtgcataa aataaaactg aatataaata
    18901 attttctgaa aaatacttgt cctaaaatat ataatatgct ataatataat caaataaaag
    18961 aaaggggtga ttccagtggg aacggatgtg gcactgccaa atgatgaaga aaactttatt
    19021 gtaatataca aaataaaatt agatactttt agtgctagat taagtactgg aaaaactcat
    19081 gagctgggat aattattgta attacctaga ctcaaacttt tagtagtaaa atagtaatat
    19141 tatatagaca aggtatctaa tttttaaatc ttttgtatga attaaaattt ttataaaggg
    19201 tatatctgat tagaatgtaa ttagggaaac ctagttgtga attactttta gtatatacat
    19261 gtgtaaagaa atatgtatat ggtattgggt attgtgctag atgtgtatgt aaaggaatat
    19321 gtgtctagtt gggtatatgt aaagaaatat acttataatc tatgaaaaat ttttagtata
    19381 aattgctaaa acattgagat tgttttttat agaaagttag tttataccaa ctaaaaatgt
    19441 gcttaagatt tgtttgatgt ttaattataa ataaggttgt agataaaaaa ataagtaaag
    19501 acaaaggttt aaaatacttg ctttaaatat agtttgtttt gaacacttgc caaattaaaa
    19561 taattaataa aatagacatc ttctcatagt aaaatatact gtgagaggat gtttttgctt
    19621 tgttcataaa cttttatgaa aaatttgcat agtgtcacat tttaatatac tatatatata
    19681 ataaaatata gataaaatta aatgattcaa aagagaaagg tgaaaagaga tgtattatat
    19741 aggtgtagac ataggaggaa caggtataca agcaggagta gttgataact atgggaagat
    19801 aatttttagg tcagagtgta aaacagtaat tgaaaaagga tttgaaggaa tacttaatga
    19861 cataaaaata atgatttata agttgttgga agataataaa cttactatga gtgacataaa
    19921 atctattgga tttggtgttc caggttttat aaataaagaa ggattagtaa cttgtgtaaa
    19981 tttaaaatgg aataaaaaag cttttaataa agagttaaaa agaagatttc cagatgttga
    20041 aattcatgga gaaaatgatg caacagtagc agcacttgga gaagcaaagt ttggaagtat
    20101 gaaaggtgct aatgttggag tattatatac tttaggaact ggtgtaggtg gaggaatagt
    20161 aattaatcaa aaagtctttt ctggagcaca tggattgggt tcagaaatag gtcatcaaat
    20221 tataggagaa aactatttta attgtaattg tggaaataat ggttgtgtag aaactttttg
    20281 ttcagcaact gcaattataa agtattctca aaaactgata gaagaaggag aaaagagtag
    20341 gattttagat ttggcagagg gaaatttaga aaatgtaaat gcaaagatgg tgtttgatgc
    20401 atatagagaa aatgatttag tggcaattaa agtaataaat agatttaaag agtatttagc
    20461 aaaaactttt gcaaacacaa taaattcttt agacccagaa attatatcta taggaggagg
    20521 catttctaaa tctagcgata taatacttga tggaatagaa ggtttggtaa gaaaatttgt
    20581 attatacaaa acagaagata tagctacaat tacatgtgca actttaggtt cagacgcagg
    20641 aattatagga gcagcttttt tataatgtaa atgaactgct tattggaggc gtgatgatat
    20701 atgggtaaaa caaatgctag aagaacgctt tttttgatag caataggttc aggaactatg
    20761 ctgaatcctc ttaattcttc tatgatttca cttgctttac atagtataca aaatgatttt
    20821 catattagtt ttacaactgt atcttggatt gtttcagcat tttacctagc tagtgctatt
    20881 gcacaaccag tttcaggtaa gataggagat ttaataggta gaaaggtctt atttttgagt
    20941 ggtttgatgc ttgtaatttt atcagcatcc atagtaccac ttgttcaatc attctttata
    21001 ttgattttta taagagtaat tcaagcaatt ggaacaagta ccctatatcc atctggagtt
    21061 gctcttatac aaaataatat aaaagaaaga caatcttctg cattagcagt tctaaccatt
    21121 tttgcttcaa ctacagcagg attaggtccg acacttggag gattattgtt ggacttagga
    21181 ggatggcatg ctatatttct tgtaaatata cctgttgttt tggtttctat atgcttaggg
    21241 tattttttat tcccaaaaga agtaaaagaa aagaaatcta taaaagaaac tttaaaaaat
    21301 gttttgtcaa gattagatat tattggcata cttctatttt caattgcaat gatttttata
    21361 ttactatttt tgctatctat gaaggaatct tttaacttag aacaacttgt atttggtata
    21421 atactgatgt gtctttttat ttggcatgaa ttgagaacaa aattgccatt tatagatatt
    21481 aagctttttg taagtaatcc taaattgtca aaagtttact tgcaatttat tatattaaat
    21541 ttctttaatt atattttgtt ttttggtctt cctagttatt ttcaagatgc cttacattat
    21601 agtgcaaagt cgactggatt atttatgcta tttatgtctg gtataggtat atttatatct
    21661 ccattaactg gaaaatggat agataaatct ggaactagat ttcctcttgt tacatcatca
    21721 atctttatgt ttattagtgc agtacttctt tcagtagttt ttatccatat acctgtaata
    21781 ggaaagggta ttatattatc attagcaggt attagttatg gagttggtaa tgtagccctg
    21841 caatcctcta tgtttgaaga aagtcctcgt gacagtatag ggacagcttc tggtctgttt
    21901 caaactagtc gttatttagg ttctatttta gcaactgttt tacttggaat ggtatttgaa
    21961 gtaaatataa catcagaaca atttcagata ttaggttatg ttatggtggt cttaggtaca
    22021 ataagttttt tattaaattt tatattaaag aaagaattaa gaaaagtaga atagtggatt
    22081 tatggattta ataagtctaa taactgataa gtttaaaaat attgtttgta aaacataact
    22141 ggtttgatat ttattaattc taagttttga agcatagagt actcgataag tatacaatat
    22201 tttgaattaa aattaagcag aaatttgaac tagtctttca aatctctgct taatttagta
    22261 gttaaatttt tttatagaga aaataagatt tgacacttag ataaaaaatc attgcatttt
    22321 caaaattctt taaatcaaac ccaagcatct cattaatctt ttccaatcta tatactagcg
    22381 tgtttctatg taaaaacata ctagtagatg tcttagaaat atttaaatca ttatttataa
    22441 attttattcc tgtatataga agttcttcgt caatagattt aatcttatta aaatctatta
    22501 atttattgag tatattatcc tcattaatta aatctaaagt tttatatcta ataaggtcaa
    22561 acaaatttaa aaacttattt tcagcgttgt cttttataat atgaggtagt aaatcagaac
    22621 ataactgtaa tctaaaatca aaatcagctt tactatctaa tttaccaaga taaaaaatat
    22681 aagtactttg ataagtttca gtttcaatta tattttgtgt agttacatta atatctaagt
    22741 tatatttaga atttactata aaaaaaccat tgtgttgtat tatatttata tcttcaaata
    22801 aattataaaa aatatttttt agatattcaa agtctatatg agattggtaa attaaataaa
    22861 agttgccttt taaattatca agattatttt tatctagaaa atcaataaca taaatagcat
    22921 tattgaaagt aactaaatgg ctactagcat ctaacttttg gttttcatat ggatagatat
    22981 ttattttttt attaagctgt ctttctaaaa aatcttttaa ctcttccata aagtctcctt
    23041 aaaaataaga ttatattctt atcttatagc taaagtagtt tctttgtcaa atatgtgtac
    23101 tctactgttg tcaactgaaa gtgttaagtc atcaccaaca ttaattctgt ttttactgtc
    23161 aaatctaatt gttatcgtat tttcgcctag ttttaagtga gcataagttt ctgctcccat
    23221 aagttctttt atttcaattc ttgatttaaa acaagtatct ggattagatt taataaaagt
    23281 atcttctaca tgaatatctt ctggtctgat acctataaca acttcattat taatataatt
    23341 gtcttttatt aaatcatagt gtttttcttt attcaattta agcttaatat gttcattttg
    23401 tgcataaatt tcatcatttt cttctattaa tattacatca ataaaattca tctgtggtgc
    23461 tccaataaat cctgcaacaa atatattagc tggataatcg tatacatctt gtggagttgc
    23521 aatctgctga actactccat ccttcattac tacgattcta tcagccatag tcatagcttc
    23581 aacttggtcg tgtgttacat agataaatgt agttccaagc tgttggtgta gcttagttat
    23641 ctctgttctc atagcagttc taagttttgc atctaagttg gatagaggtt catccattaa
    23701 gaatacctta ggatttctaa ctattgcacg tcctaaggca accctttgtc tttgtcctcc
    23761 agataatgtt ttaggttttt tatttaaaag aggtagtaag tctaatattt tagcagcttc
    23821 tttaactttt ttgtctattt catctttagg caattttcta agtttaagtg caaatgccat
    23881 gttttcgtaa acagataagt ggggatataa agcatagttt tgaaaaacca tagctatatc
    23941 tctatctttt ggttctatat catttacaag tttatctcca atgtatagtt ctccttcaga
    24001 gatttcttca agaccagcaa tcattctaag tgtagtcgat ttaccacaac cagatggtcc
    24061 tactaaaacg ataaattctt tatctttaat gtctatattt atatttttta ctgcattaaa
    24121 tccatttgag taaagttttg atatattttt taaaattact tctgacataa tatcctcctt
    24181 gatatttaaa ttttaattat atagtatcaa atttttttat tatattaaat gtgtaaaatg
    24241 actaaatgta tttgtttaat atgtatatta aaaatttaga ctaatagttt tttaatttaa
    24301 aaaatgtatt ttaatttaga aaagttttat gtataatagt atatagtttt tagttcaaca
    24361 acatgggatt taaatgtcaa tttaatttat aaggaaatag tattatatta atagtttaga
    24421 ttaacaatga ggagtataaa aataaaataa tataattaag attgtattga ttgtatataa
    24481 ttaaatttct agtaaattta gttatatata attatattta tccggtcaaa ttaattatat
    24541 agaaataatt tattgactct atataagtaa tatcatataa tgtaaatatg atttaataaa
    24601 tataaaaata cataggggga ataaatatga atttaaacag aataaaagaa ataattaaga
    24661 aaggattaaa aagatttatg aaagtagtag taaatttatt ttgtaataaa ttatttcatc
    24721 gcatgttata cattatttct atttcagtag tagtaaaaat cacaatggac ataaatttat
    24781 acatatctat tttaaaatat taactatttt gtaaatataa aaaattaata gagatatatc
    24841 tattaatttt ttatattaca aatagagaat aatgaattat actagaaagt aggaggtgaa
    24901 aatatgagca gaatttcaat ttttatggaa tcatgtaatg gcaaatttcc aaatgaaaat
    24961 tcaatgttgt cagtttcctt tataaaaaat attttaaatg cagaaaacaa agattttgct
    25021 aaaaacatat ttaactatgg ggaagaaaga aaaaacaata agcaaataaa ggatataaat
    25081 acagccattt acataccaaa tcttataaga agcaaaaatg agttacttgt tgatggagat
    25141 ataatattca atataagttt ttataattat tctatgttca gtaaattata caatggaatt
    25201 ttaaaagtaa aggagctaga atataaaggt tatagattta aaataaaaaa tataaaaata
    25261 cataaagaac acgagataaa agaaaatggt gttatattta aaactatgtc tcctataata
    25321 gtaaagaata aagaaggtaa atatttagat gtagaagatt caaattatat agaatgttta
    25381 aactatatag ctaatctaac tctggagagt ataagaggta gtgggcttag aaagccattg
    25441 gaatttatac ctcttaactt caaaaaaaga gtgttaaaag aaaagattcg tggatttaaa
    25501 gagagagaat tttactatat aaatgcttat gcaggaacat tttttttaaa aggaaatatg
    25561 gaagatttaa atgcactgta taaaatggga attggatata gaaggacgga aaatgcagga
    25621 atggttgata tattaaagta gcgaggtgag agaaataaaa gctaaatttt atagatcagg
    25681 tgatattgta agagatattg gcattgttta cttttgtgaa ttactaatgg atttaaaaaa
    25741 cgaactagaa aaaaatgatt ataagctaaa atttacttgt gagttgaata gaaattattt
    25801 atctttagaa tctgcagaat atatagaccc taagtatata tctgattata tattagaaaa
    25861 tcaacttttt aaggtattta aaaatgggaa aaaggaaacc ttagaaaaaa tatttagtaa
    25921 tatagataat ttaacatatg taaattttat tgaagaattg gataaatctt ctgcaactga
    25981 gaaacaaaag gaagggatta aaaaagattt taaaaacaga agatttccat atgttagaaa
    26041 tagtggtaag tatggattaa acacgagtct agaaaatatg gaaacaaatg taaaaagaat
    26101 agtcgatatt gtgattaaat caaatataga gatagatgaa atagataaac ttgatttgaa
    26161 acaatatgaa gaaaaagata gtgtatgtaa tgtttgcaat ataaataaaa caacaaaact
    26221 agatattgat ttaagagaac gaaaggactc taagtataac tttttattta gaggtgcaga
    26281 aaaatcaggt tttaaaagaa gtggacaagt tgaaagtaat atttgttttg agtgtgaatt
    26341 tttcaactta atgtgtcttt tatatataaa tttaaaaaga ccaatggttt ttgcatatac
    26401 gaatgattta agagaattag catttttaaa tcataagata atgcttaaaa gaaaaatgta
    26461 ttcagataaa tcattttata aaaaactttt gcatgaaaaa ataagttcaa ttagactata
    26521 taggattgat attgatacga ataaaggtat aattctaaaa tttgactcta ttatagagta
    26581 taaagaatta ttaaaaaaaa ttgaacttat agatattata gataattata atttttcaag
    26641 agagccaatg aatactagaa atttgggtaa aaaaatgatt aataatggga atttatcaaa
    26701 tttaaaagaa ttattacttg ataatataag tgttttaagg caactaactg gaacttctcg
    26761 agaaatggat tttgtatcta gttcatataa tatcggttta tatataaaat tgtgttggat
    26821 tgtagatgga agggaggagt ataaaatgaa aaactatata gaaagtaatt taatatattc
    26881 aagagtaggt aaagacttat ttaataaaat gacagatgaa tccagaagaa aaaatttttc
    26941 tatgaaagtg attcaactac ttaagtctaa tgatagaact cagctatttc aaactataat
    27001 gcatgtgtta gtttctaatg gaatcttaat aggagaaggg tttgtagaag gtctaatgca
    27061 gagttctgaa ttagaattaa atacgaatgt aggtctattt attcaagaaa tcatgaaata
    27121 aaaaaggggg aaaatttaaa atgaatgaaa aaagagtaaa aggagtaaca ttaactatac
    27181 tgacagaaag cccagttcca ctttcgtatg accaagggta tggaaattat acaccaataa
    27241 aaaaagaaca atatagagat aaagtacatg caaaaactag tatagctaca ataacatatg
    27301 atttaagaag aatactccat caagaatatg gttggaattt aagtaatatt gtttttggaa
    27361 aaaaaggaaa tatatatcca tctattaaga aaaatgtagg atgtgtagat gaaaatggat
    27421 tagagactga tgtatttggt tatttaatac cacttaaaga gaaaggttct ataagtaagg
    27481 cttctccgct tagaataata ccttttaggt cattaaattc atatagaggt tcaacacagt
    27541 tgataacaaa tagaggtttt ttaagtagcg aatttggtag aaaatattat gatgagaggg
    27601 aagaaaatga agtacttaga gatgaaaact ttccaacaac acaagcatta gcaatagaag
    27661 agactttatc agattactac gtttatacaa taacattgga gcttgataga ataggagtag
    27721 tagaagtaga agaagatgga aagttacttt taccagaaga aagaaaattt atgagtaagg
    27781 agttaagaga aaaagcagta aaagatatat tagatgcaat tactgtgttt acaagaaaca
    27841 taaaacattc atcagtacta ttaaaaccac ttgcagtaat gggtggagct tttgataaag
    27901 ttgtaccatt tttttgggat gatgtagatt ataatgctga tagtggtgag ataaatttag
    27961 agggagtcat agaaactata gaaagttata gccttaaaga aagtaa
//
LOCUS       DAFAZV010000055        27482 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFAZV010000055 DAFAZV010000000
VERSION     DAFAZV010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 27482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27482
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.055"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            52..921
                     /locus_tag="KOU88_003243"
     CDS             52..921
                     /locus_tag="KOU88_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBK3213097.1"
                     /translation="MVIIKAIELYKKLDLEFNIKNINDDWSFMNFENDFITSEFRKKY
                     IGLVLDNAQNINKVYTTTFPDKEIIKQVIDKDEKDILIFSHHAMGYIASDEGFPFHDI
                     PLSYMEEMKNRRISFYVLHSPLDNYSDYSTSVSFAKAMGLEIVKPFCKYDDKIEVGVI
                     CKTSLKSIEEIKELIKKSVGHDVKLYDYGDSVLKDGLVAIAAGGGSYPFVAREVAELG
                     INLYITGFTKPLKHFEPVLEFHQIAKDNLINVIGATHYSTEKFACMGMVDYFKNLGLE
                     SEFLQGKYYLEDL"
     gene            1725..2432
                     /locus_tag="KOU88_003244"
     CDS             1725..2432
                     /locus_tag="KOU88_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK3213098.1"
                     /translation="MIFTKSNKYDKDFLMKNMMGPNCIKILEELTSKIKLEKGMRILD
                     LGCGKGISSIFLAKEFDATVFATDLWIEPTENYKRFKEFKLDDKIFPIQAEAHELPYA
                     EGFFDAVISIDSYHYFGNKEGFLDNHISPLVKEGGILAMAMPGLKEDFVDCIPDELIP
                     FWQDNMNFHSITWWNKLWSESESVIVEKCEALNCHDEAWKDWINCDNSYAINDKKMME
                     VENGKYFNTISLIARTK"
     gene            3044..3544
                     /locus_tag="KOU88_003245"
     CDS             3044..3544
                     /locus_tag="KOU88_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3213099.1"
                     /translation="MIEGIKFIKAEEKYIYSYWQTFDKIAKERKYLAMDEAFPFEETV
                     EFIKNIINKNLPQLFIIDLESDNCIGWCDVLPKTEKVGYLGMGILKEYREKGIGSSLL
                     KQIIDLSKEYGYEKIELDVFKSNSRAIHVYKSLGFVEVNTISSGFTWNDRPVKEEVIQ
                     MELTLI"
     gene            complement(3794..4573)
                     /locus_tag="KOU88_003246"
     CDS             complement(3794..4573)
                     /locus_tag="KOU88_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213100.1"
                     /translation="MNKNILNNSFPEVPESFHNSLSKTLNSLPEREENYKMINNKTHK
                     LPFRKGLVATLAITLILSTTALAVGHIYSLVGKSSTKATYTSIPTTEQVKKDFNFTPN
                     IVSEFSNGYKFKGAYTVNKKAFDKENNVLGKSKALSFEYKNGNDEISLDTANDVLGKS
                     SDNLKVVDTYKDINISYEAFAQKFVPEGYKMTEQDKIDEKSGKYTFSVGPNNESDKVE
                     VNKFKFLTWKQDGVYYSFTVQDSNLSMNDLVKMAHEVIDAK"
     gene            complement(4570..5049)
                     /locus_tag="KOU88_003247"
     CDS             complement(4570..5049)
                     /locus_tag="KOU88_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3213101.1"
                     /translation="MDKTTFTNNILESEQTLYRVSKSILGNDQDCEDAINNAILKAYE
                     KLDSLKEEQYFKTWLIRIVINECNSLRRKRLKSLSFEDVFKNKKIDEKDDYSDLYTAI
                     QSLPKKIKIPIVLYYIEGYSVDEVKEILDIPQGTVKSRLSRGRRLLKTKLENTEVII"
     gene            5858..6559
                     /locus_tag="KOU88_003248"
     CDS             5858..6559
                     /locus_tag="KOU88_003248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5058 family protein"
                     /protein_id="HBK3213102.1"
                     /translation="MKFQEMINSPGLWIVSSFLVIISVVQAIVFMKEALKEASNLGIE
                     RKGIKAAIRSASVTAIGPSLSPVITLLSLVAVIGAPTTWMRLCDVGAARTELGVISLT
                     SNLSGVEVGSAAFGAEAFSYALWGMALNNLGWLFVVFILGHRMRGIVEKMNMKYNPTW
                     VKKLLAGATVGLFAYLLSNQIKTFEIPKLTPAIISAIVMLVLTTLFKKNQRLQELSLG
                     IAMLIGMFGTQIILS"
     gene            6585..7241
                     /locus_tag="KOU88_003249"
     CDS             6585..7241
                     /locus_tag="KOU88_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213103.1"
                     /translation="MYDKKMIKIGRISIGLAIIANFIPAIYVGIRFGQMPMLSVIFQI
                     WGLVAATYGVSWIVQPIAYYPTLGAPGSYIGWLAGSVGDIRMPAASMAQKIAGVEAGT
                     HEGEVVGTIGTCCSIFVSASMITIFTIVGYKVIPLLPEFVTNSFNYILPALFGAIYVD
                     IARKDIRAGGCTIAVALAIMYFGEKIGIPGGLLTLFIVLGGILITRVFFVIDNNKTKE
                     "
     gene            7346..8986
                     /locus_tag="KOU88_003250"
     CDS             7346..8986
                     /locus_tag="KOU88_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aminoacylase"
                     /protein_id="HBK3213104.1"
                     /translation="MFDVKIVNGIIVDGTGNSRYKSDVGIVGDKIMAIGDLSQKEAKE
                     TIDATGKFVSPGFIDFHTHSDLSLVYDKYTRSRIHTGVTTDVIANCGIGVAPIREEKK
                     QELIDYLGTRIIGTIPTKLELHWNTMQEYFDYLTENSPAVNVVAYVAQGPVRINEMGF
                     SKEPATLEQLKNMKLEVRKAMEAGCVALSSGLVYLPGAYTKKEEMAELCKELIPYNGY
                     YISHIRDEGDEEMEALDEAIYIAKTAGVPLHVSHLKVMGHKNFGTIDEVFKKLDEAEA
                     DGLEVTFDCYPYTAGMTSLGALLPPWAFEGGVENMVKRLEVQENRDRIIKELEEGIPG
                     WQCFYQLAGGWNGVVLASVMTEANKYVEGKTLMEVAKINGENPFDTFFRLLIEEKSKI
                     QVVVHTQGQEDTDKVVCHPKSCIGSDSMDLSTEGLLSLGKPHPRAFGTFGRIFSYYVR
                     EKGMLTFEEAVKKITYLSAKRLGIYKERGLLKENYFADIVVFDPDTIEDKATYSNPKQ
                     YTVGVEYVLVNGKIALAGGKQTDVCAGRVIKNPLSIAK"
     gene            9344..10666
                     /locus_tag="KOU88_003251"
     CDS             9344..10666
                     /locus_tag="KOU88_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213105.1"
                     /translation="MKILYVGPGMVIDKILAVSKKNFPNIEADFLRYDRYIEVPDLLE
                     KYRGRVDAVLFTGKSPFKFFEKRQKDFVLSDYIPRHETTLYRVLLEITYLLKFDISRL
                     SIGTYDKAMMKRLYKEIGVEFKDEHMFFAEQKYLEEDYIKFVLEFHKYNYQNNDVCCC
                     ITGLEEAYHIMKKDNIPVVLALPSEDVMVQSIKNIQMRYIAKKNNENQIIVLAIKLNM
                     PSEYSLMKEDEYAYLSQRIKILDKLYHFNSRIDGVLVEQSRSEFMIFTTKKILELETK
                     KYRDIYLLDMIREVSVINTYIGIGYGKTANEAKFNAYESIKMAQSQKNDAAYVVFENG
                     EIMGPLKPNPTVKEKNSFDERFYQIATETGLSANTVYKVFNKIINSGKTEFTSKELAT
                     ICGVSIRTMDRIILRLCDSGYCEVVSEQLMSKYGRPSRILRFKPFLLF"
     gene            10863..11870
                     /locus_tag="KOU88_003252"
     CDS             10863..11870
                     /locus_tag="KOU88_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBK3213106.1"
                     /translation="MGKYQDSKKVVRNYFEALENATGDEVENVLKQHMKSDYNWKGVY
                     PFREQEGTENVADVFWKPLKKSLSNMQRRQDIFIAGTNEIDNSEWVMSMGHFMGLFDK
                     DWLGIKHTRKMISLRYAEFNCVQDGKIAKTGLFVDIIGFMIQAGVNPLPPQTGSYFVY
                     PGPIDHNGLLFEDADEVEGVKTLALVNKMVDDLSELNESGAMGCPPEILEKSWAKDMI
                     WYGPGGIGASYTIPRYQEQHQLPFRNNLKGKTFNGHVCRFAEGNFACFFGWPNLTNVP
                     CGGFLGLPGGEVKADMQVVDVYYRKGDKLQENWVLIDIPYWLKQQGLDILERTKSIFN
                     A"
     gene            11908..13335
                     /locus_tag="KOU88_003253"
     CDS             11908..13335
                     /locus_tag="KOU88_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ester cyclase"
                     /protein_id="HBK3213107.1"
                     /translation="MASTNKNNATSKEEEKEVSTSGLESCTVKENKAKMNQTNFSNIN
                     ENQTNENKTNTYKRNIDKGNIDKGNIDKTNTNKSDINKVNIDTVDTDKLNTNTLTEKN
                     KKVIFKGEDNMSSTKIYYGDSLEVTPVGVMDYNDFSKQTKREQEIPGFDSKYRDFVDY
                     IMKITHNIWEEKGIGVIYDTYHNNVTMHCGSSNLVGIKDVISNTLQTLHAFPDRRLIG
                     QNVIWSNFGADGFLSSHRVLSTATNLGDSNFGPATGRKINFRTVIDCATTNNRIHEEW
                     LVRDNLWIVTQLGLNPQEVAKSMAKASESKVLSLQSTYGICESMDGQFMPTKYQAKDD
                     SVGEMMLEMTSRIYNYKYINEVKKYYHDNAVVHFICDKDLNGYDEIQGMIVSLFASIP
                     NGSYEVERVTCNQREKNEGYDVSVRWRLRGINEGIGFFGQPSGKHIEVMGINHYHILQ
                     GKVKEEWITFDGMDVLKQIYMGVEE"
     gene            13477..14742
                     /locus_tag="KOU88_003254"
     CDS             13477..14742
                     /locus_tag="KOU88_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3213108.1"
                     /translation="MKTTVEIENDIILGKDYSNLKRGIAFFSIALIYFFYCYNFMVGT
                     FIKPTMIYALADGGFGFSLKQTEEIFAVMSFGTIPGTFIFGVISTKIGKKRTLISVAL
                     LIGLTTFIPMLSPTNIMLWKIARLCTGVVLGGVFGTAMPLVADMFPSKYRGKLAAILT
                     ALFSLAMIFGGKVYGVLGDANWQILMYTAIIPPIVGAILAIFFVPDDLEYTKELVKKG
                     KETGEKISYISMYKGKYLWIGLGTILLSGANFTAYSAFSNNATTYLVTGIGMSAAVAE
                     SIYSLQGIGQLVGYLFWGSIADKFGRKIPFIGMALAAVFVFIYTKLGGDNTTTFYMIS
                     VLLGVAVGYSGAWGAYYTELFPSKYRSLSSGMSFNGGRIISTFAIPAIAGTASGTLGM
                     MTIFYISIAVFVAGAIVWLFLPETLNNKK"
     gene            14784..16382
                     /locus_tag="KOU88_003255"
     CDS             14784..16382
                     /locus_tag="KOU88_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HBK3213109.1"
                     /translation="MISSIDVCIIIGYLLLMLVIGYYSGKDNKNQEDYFLAGRSMPWI
                     PIALSVAATMISANGFIGGPGWAYVDGMYPVMVNITVPLAIFFALSITTPVIYKLKIT
                     SIYEYMGLRLGNYSRGLTIIQFFINSLIQASSMVYIPVLIIQMITGWSLYALVPIVVL
                     VSIIYTLLGGIKAVIWTDSIQMIVVISAVFIVIIVALKGMNLSFFDTLQIAQQSGKLN
                     TFDFSRDISVTNTFWATLIGGTVMWIRYFCFDQSQVQRVLTSKSLKCAKNSFVVSAFV
                     MNLVYYFMLLVGVILFVFYGGRTFETSNEIMITFILNELPVGAIGIIIAGVFAAAMSS
                     IDSILNSMTTVFTKDIYEFYFKKDNKESSLKVTMIITVVIGVVMTGFIIMGFGGSIKS
                     ILDLVGNYISYFAGPATGAFVLAMFTYKANDKGVSIGFIVGLVLGFFISNKYNVSWLW
                     NPAIGATITLIFGYIFSVILKKNHNADDIKKYTAFGMRNHLISQGMDKVDGVSIVPFS
                     LGKQELIVLAFFIIQYIILFLIQF"
     gene            16417..17439
                     /locus_tag="KOU88_003256"
     CDS             16417..17439
                     /locus_tag="KOU88_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK3213110.1"
                     /translation="MNQKKVHYNKSATSKDVARLAGVSQSSVSRAFGSANGKGVKPEV
                     RERIFRVANEIGYVPNLVARGMISGKTNVIGLIVGDSLGPFYNRIINLFVEKIQEIGK
                     QCLVFKVPRQQSIDSIISKVIQFQVEAVIITASAMNKVMAETCEENNIPVILFNRFIP
                     GIKISTVYVDPIEGGGMAAEYLLKKGHKNIGYIQFTRETSEEMEKKIGFYSKLRQSGI
                     HNLKEESANYDYDSGYEAGKRMLALSNPPTAIFCTSDLIAIGVMDAARFEYKLRVPED
                     LSVIGYDDIQMASWKSYNLTTIRQPLDLLIEKTINILKSLLNEENPESVVEMLKPELI
                     ERGSTL"
     gene            complement(17897..19300)
                     /locus_tag="KOU88_003257"
     CDS             complement(17897..19300)
                     /locus_tag="KOU88_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3213111.1"
                     /translation="MKMLNNFFKKINNPAPVFAQTKMERDNQTDDSLSTKPKTTFRDV
                     AGLDEVKEELFEIVDFMKSPQKYQKMGAKIPKGVLFYGPPGTGKTLLASAVAGETNSS
                     FFNVTGSEFVEKYVGVGAKRVRTLFEKARKEAPSIIFIDEIDAVGAKRHLESNNEKDQ
                     TLNQLLVEMDGFNKDSNVLIIGATNRLDLLDEALLRPGRFDRHIHIGAPNYHTRFEIL
                     KVHTDDKPIDKSVNLELLAKKTHGFNGAHLSNIANEAAIFAVRDDSECITSEHFDKAL
                     ERVIAGLESKNSALVEKEKKIVAYHEAGHALVSDIVGICPIQKISIVPRGQALGYVLQ
                     LPDEDRYIYTKDELIGKIKILLAGKASEELIFNHKSTGAKDDLKKVTEIANQMVCEYG
                     MSNLGFMTIDGNDKTFLCDKVQKEANRIVEICYKETLEMLKDNLEDLHSVSKFLFEKE
                     TMTHEELKDLIGKEAVN"
     gene            20473..20982
                     /locus_tag="KOU88_003258"
     CDS             20473..20982
                     /locus_tag="KOU88_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009528606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBK3213112.1"
                     /translation="MSKELAINEQIKDKEIRVLSPTGEQLGVMPTKEAQAMANSKNLD
                     LVQISPNANPPVCKIMDYGKFRYEQARKEKEAKKKQKTIVVKEVRLRPGIEQNDLNTK
                     ANNAIKFLKKGDKVKVELRFRGRELGHKDIGKEVMLKFLDIIKEFGEPTKAPAFEGNN
                     MVVIIDPKK"
     gene            21010..21204
                     /gene="rpmI"
                     /locus_tag="KOU88_003259"
     CDS             21010..21204
                     /gene="rpmI"
                     /locus_tag="KOU88_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBK3213113.1"
                     /translation="MPKMKTHRGAAKRLKKTGTGKLKRAKAFKKHILTKKSAKTKMNL
                     RKSTLVSDGDAKRIAQLLPY"
     gene            21260..21616
                     /gene="rplT"
                     /locus_tag="KOU88_003260"
     CDS             21260..21616
                     /gene="rplT"
                     /locus_tag="KOU88_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBK3213114.1"
                     /translation="MARVKKAMNARKKHKKILKLAKGFRGSRSKLYRPANTFVMKALK
                     NAYIGRKLKKRDFRKLWIQRINAAARMNGISYSRLMNGLKLSGVEVNRKMLSEMAIQD
                     PEGFAKLAEVAKAKLA"
     gene            21926..22471
                     /locus_tag="KOU88_003261"
     CDS             21926..22471
                     /locus_tag="KOU88_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213115.1"
                     /translation="MNEKLMDCFVNPIKCKLLIEIFSNNRTTAKQLGEKFQDISKATL
                     YRYLNKMLKDDIIKVVEENKIRGTVEKVYAMKLDIADDVNKIIDENSGEEYAQLFTQY
                     MMGFLREFYEYAERKEKDILKDGSGFSVCPVYASIDEIVEVSKKIASILEPLRNNSHE
                     EGRRMHSIGVIITPPKEDEGK"
     gene            22458..22631
                     /locus_tag="KOU88_003262"
     CDS             22458..22631
                     /locus_tag="KOU88_003262"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213116.1"
                     /translation="MKGNKSDLHEVEPIYTENRFMIYICIQSKVSLLGLYFIVPFHPM
                     TWSGTMKFFNFSY"
     gene            22906..24831
                     /locus_tag="KOU88_003263"
     CDS             22906..24831
                     /locus_tag="KOU88_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK3213117.1"
                     /translation="MKIKFVIMPLVIFLMVLFVGCQSTKDTEVKAKDTEIKILGTGDL
                     HSILTDSMVSYVNEEREKNKNLLMVDAGDFYGTQSREMWEWSSGKKLINIKRNGRAEY
                     DDIIKSSKDEVPIVKDMAKLKYDAVVLGDNEFVSNDKQSLDKLVSDFKNNNMPLVSAN
                     IYEQSGENYVQPYVMKNIKTDEGNVKVGILGLTIKEVGETLGLEDFEKDKKARELGEQ
                     ADYKGKLYANDLVEDAKKWIKVMEKESPDIIVAVVHSGEEPKTDRNPGNRIKELATTV
                     DGIDAIVAGHTHEKIDEHKYKNKSGDEVIVTQPGWHGDRVSEINFKLNKENGKWDIKE
                     KSSKLKIIDKEVSIVATADLHSHFSDKLTVDLVNERSNPIEPVVVDAGDFLDPQTDEM
                     TQWYKEWKSIRDNNSDKTISRCPMVMDMNQGMYDAVVLGNHEFVSEKDEFWSDERLLD
                     AVIEDFEQVAISVLSANIYRQSGKNYVKPYIIKDVETSEGNVKVGILGLTIKEVGKGL
                     KNVNLQEQFQYKDKLYANDLVEDAKKWVKVMKKKKPDIIVAVVHSGEEPKNPKHPGNR
                     IKELATTVDGIDAIVASHTHEKIDEHEYKNKSGEKVIVTQPGEHGKYYSKITFKVNKE
                     KGSWIINDKFSKTIEVE"
     gene            25232..27136
                     /locus_tag="KOU88_003264"
     CDS             25232..27136
                     /locus_tag="KOU88_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK3213118.1"
                     /translation="MKIKFIIVASIIFLIVLLVGCQSTKDTEINVLATSDLHSIIPDN
                     LISYVEEERKYDENLLMVDAGDFFDMQSGEMNKWFTGQKLVRFKDGIPEYKKIAEPRE
                     GEVPLAKKMAKLKYDAVTFGNHEFVSNDKQSLDKLVSDFKNNNIPLVSANVYEQSGEN
                     YVKPYVMKNINTDKGTVKVGILGLTIKEVGERSRFKSFEQDKKARELGEQPQYKGKLY
                     ANDLVEDANKWVKVMEKKEKPDIIVAIVHSGEEPKNPKNPGNRIKELATTVEGIDAIV
                     AGHTHEKIEQHTYKNNSGEEVIVTQPGAHGNSISKINFKLDKKNDKWFIKDKYSELKV
                     FGKEVNIITTSGLNPKFSDEMAVNLFNERDRDVQPIFIDTGDFLNTNTKEMTKWAKEW
                     QYNENKGIYKKINEWPIVYLGYDAVVLGSHEFTEDKETFEEKKSTLDYIIENFEEMKI
                     PVLSANIYDESGENYVKPYIIHNVETREGNIKVGVLGLTTTDKDEEDLSNSSLSKDSK
                     TSKIPEETGKLYTNNLVKDASEWVKVMQKESPDVIVAVVHSDNNSTLKNPSSEVKKLA
                     MSVDGIDAIVVGHTKNKVEEHIYKNKSGDEVIVTQSGEDCYSKISLELRKENGKWNII
                     NKYSKAIKMK"
BASE COUNT        10379 a         3016 c         4901 g         9186 t
ORIGIN      
        1 atcgtgaaat ttctatatta atatgtagta attcaatatt attataaagg agtggttatt
       61 attaaggcaa ttgaacttta taaaaaatta gatttagaat ttaatattaa aaatattaat
      121 gatgattgga gttttatgaa ttttgaaaat gattttatca cttcagaatt tagaaaaaaa
      181 tacataggat tagtattaga taatgctcaa aatattaata aagtatacac aactactttt
      241 cctgataaag aaataattaa gcaggttata gataaagatg aaaaagatat tttaattttt
      301 tcacatcatg caatgggata catagcatca gatgaaggtt ttccatttca cgacatacca
      361 ctatcttata tggaagagat gaaaaatcgt agaatttctt tttatgtatt acattctcca
      421 ctagacaact atagtgacta ttcaacttct gttagttttg caaaagctat gggtttagaa
      481 atagtcaaac cattttgtaa atatgacgat aaaattgagg taggagttat atgtaaaaca
      541 tcactaaaat caatagaaga gattaaggaa ttaattaaaa aatctgttgg tcatgatgtg
      601 aaattgtatg attatggaga ttctgtatta aaagatggtt tagttgctat tgcagcaggg
      661 ggaggaagtt atccatttgt agcaagagaa gttgctgaac ttggtataaa tctatatatt
      721 actgggttta ctaagccttt aaaacatttt gaaccagtat tagagtttca tcaaatagca
      781 aaagataatt taattaatgt tataggtgct actcattatt ctacagaaaa atttgcgtgt
      841 atgggcatgg tcgattattt taaaaatcta ggtttagaat cagaattttt gcaaggaaaa
      901 tattacttag aggatttata ggacatatta aacaataaaa ataaacagtt agtaaaaatt
      961 tattttacta actgtttatt tttttaccta tttatccagt gttttgaaaa aatctatctt
     1021 tattttttaa actaagaaaa tagactttta attgctgatt agaagattta gttttgatgt
     1081 cttttaaatt atttttcgat attttttagt ttattttttg atgtatttta gattattatt
     1141 taggattgat tagaatttat aaatatttat tttagattat tataaatatt tattttaaaa
     1201 aaatagaatt attatattta tgataataaa tggtataata aaaggtaaag tgtcaaatat
     1261 gcactaaatt aaataagtta attagtatat aggttaaagt ggaagtaatt aaaacttatt
     1321 aagtattaga aaatgacttc ttattagagt aagtatctaa aatgatataa aaattatgat
     1381 tactcattaa agtgactatt atagagtgga taagattact cattaaagcg attactgtag
     1441 agtagataaa attactcact aaaataacta tcatagagtg gataagatta ctcattaaag
     1501 cgattgctgt ggagtagata aaattaccca tcaaagttaa ctatcacagt agataagatt
     1561 attcattaaa gttactatca cagagtggat aaaattacac attaaaattg tctgttaaag
     1621 aatgaataaa aaagagattg ctcaatataa gaagcatata aaaaataaaa aatcaaacgt
     1681 ataaaattta ataaataata actgataggg aaaggaaaga tagaatgata tttacaaaaa
     1741 gtaataaata cgataaggac tttctcatga aaaatatgat gggacctaat tgtataaaaa
     1801 tattggaaga attaacaagt aagataaaac tagaaaaggg aatgcgtatt ttagacttag
     1861 gttgtggtaa gggtatatct tcgatatttt tagcaaagga atttgatgct actgtatttg
     1921 caacagattt atggatagaa ccaactgaaa actataaaag atttaaagag tttaaattgg
     1981 atgataaaat atttccaata caggcagagg cacatgaact accttatgca gaaggtttct
     2041 ttgatgcggt gataagtatc gattcttatc actactttgg aaacaaagaa ggatttttag
     2101 acaatcatat atcacctctt gtaaaagagg gaggaatact tgctatggca atgcctggat
     2161 taaaagaaga tttcgtggat tgtataccag atgaactcat tccattttgg caagataata
     2221 tgaacttcca ttcaattaca tggtggaata aactttggtc tgaatcggag tctgtgattg
     2281 tagagaaatg tgaagcttta aattgtcatg atgaagcttg gaaggattgg ataaattgtg
     2341 ataattcata tgctataaat gacaaaaaaa tgatggaagt agagaatgga aagtatttta
     2401 atacaatttc tttgatagcg agaactaaat aattgtgatg aatttataaa agtataagat
     2461 aagtagaaat ataagttgaa tgagagtata agaagcatag aaatataagt tgaattaaag
     2521 tagaaggtaa ataaaaatgt aagttaaata aagagtttat acaaaaatga ttttttagat
     2581 tatttatacc caatcgagtt gcttaggtca gttgggtatt tttatttttt taaagttaaa
     2641 ttgcaaatac tattgtgtga tatatatttt aatactaaat gtttgtttta taagaaataa
     2701 actaatagaa aaaatagctt taacaatgaa agcaaaaaag gtattgatga agactaaaaa
     2761 ttttatagta ccattttata tattttttta tatattttat tatactttaa atcaaatttc
     2821 aaaatgatta agtatatata ctcaaaagat taaagagcta tatttattat actattaaaa
     2881 attattttaa tagagataca agagatagat atattggttt taattttata gaaatataca
     2941 aagatatttt aagctaatat atagtaattt atatagcatt ataaaataga atcatataaa
     3001 ataagttaac tacaatcaaa aattaaaaag gggaaatgtt aagttgatag aaggcataaa
     3061 atttataaag gcagaagaaa agtatattta ttcgtattgg caaacttttg ataaaatagc
     3121 aaaagagagg aaatatctag ctatggatga agcctttcct tttgaagaaa cagttgaatt
     3181 tataaaaaat attataaata aaaacttacc acaactgttt ataattgatt tagaatcaga
     3241 taactgtatt ggttggtgtg acgttttacc taaaactgaa aaagttggtt atctaggcat
     3301 gggtattctt aaagagtata gggaaaaagg tatcggaagt agtcttttaa aacaaattat
     3361 tgatttatca aaagaatatg ggtatgaaaa aattgagctt gatgtattta aaagtaatag
     3421 tagagctatt catgtttata aatctttagg gtttgtagag gtaaatacaa tatctagtgg
     3481 ttttacatgg aatgatagac ctgtaaaaga agaagtaatt caaatggagc ttacacttat
     3541 ataaaataaa gttaaagtct ttaaaattcc atatacactt gtataaaata aagttaaagc
     3601 ccttaaaatt ccatataaaa gaaatatttt taagggcttt ttaataatgg ttcttttgaa
     3661 ggtagctaaa tatctaaaat tttatatatt aaatttaaag aaaatataaa gatggaagat
     3721 acaaccatgt ttactaataa aaaaattaaa gtcataaata ataaactcat aaacaactta
     3781 ttattactta tgtttatttt gcatctatta cttcatgagc cattttaact aagtcattca
     3841 tagataaatt tgagtcttga actgtaaaag aatagtaaac tccatcttgt ttccatgtca
     3901 aaaacttaaa tttattaact tcaactttgt ctgattcatt atttggcccc acactaaatg
     3961 tgtatttgcc tgatttttca tcaattttat cctgttctgt cattttataa ccttctggta
     4021 caaacttttg tgcgaatgct tcataagaaa tattaatatc tttgtaagta tctacaactt
     4081 ttagattgtc agaactcttc ccaagtacat catttgctgt gtcaagagat atttcatcat
     4141 tgccattttt atattcaaaa ctaagtgctt ttgattttcc taaaacatta ttttctttgt
     4201 caaatgcttt tttatttaca gtatatgctc ctttaaattt atatccatta ctaaattcag
     4261 aaactatatt aggggtaaag ttaaagtctt tttttacttg ttctgtagtt gggatagatg
     4321 tataggtagc cttagtactt gattttccaa ctaaactata tatatgtcct actgcaaggg
     4381 ctgttgtgct caatatcaaa gtaatggcta aagttgcaac taagcctttt ctaaatggta
     4441 atttgtgtgt tttattatta atcattttat aattttcctc tctttctggt aaactattta
     4501 gtgttttgct taaactatta tgaaaacttt ctggaacttc tggaaacgaa ttatttaata
     4561 tatttttatt catatgatta cctccgtgtt ttctaattta gtttttaata atcttcttcc
     4621 tcttgataat ctacttttta cagttccttg aggtatatct aatatttcct taacttcatc
     4681 tactgaataa ccttcaatat agtaaaggac tattggaatt ttaatttttt taggtagact
     4741 ttgaatagca gtatacaaat cgctatagtc atctttttca tcaatttttt tgtttttgaa
     4801 gacatcttca aatgatagag attttaatcg tttgcgtctt aatgaattac attcatttat
     4861 gactattcta atcagccatg ttttaaagta ttgttcttcc ttaagagaat ccaacttttc
     4921 atatgctttt aaaatagcat tgttgatggc atcttcacag tcttggtcgt ttcctagaat
     4981 agacttagat actcgataca aagtctgttc tgattcaagt atattgtttg taaatgtagt
     5041 tttatccaac taagttcctt cccttctatg caaatcgtag cgctactttt ttgcctttca
     5101 cttattagat aaaattttac tatagatggt tcactttttt tatgattatt tgataaattt
     5161 aagtttgaaa gttttgccta ttctatacaa atattctata atatattttt ttctagtatt
     5221 ttcccctcat atataaagcc atgtagatat attaaacttt agaagccatt tatatattta
     5281 gttttatagt aagtgtttat attgagtaaa ttagaaaata gtaagtattt aatgttgagt
     5341 agttagaata acaatgcttt tggattattt acttcatgta cagatttaaa ataagttttt
     5401 taaataatga gtaaagataa cagtatcttg actaaaagta ggcttttaag aaaaaacaat
     5461 gaaacttaaa tgagaattaa gagttagaaa tgtcattatt ttagatagag atgaacataa
     5521 ataaacttaa aaaatataaa ttataaaaat aataattttt tttaaaataa taaagttttt
     5581 tgattaaaag ttttatattg aaatgtcaaa ataataaaag accttataag ttaattacag
     5641 gttaaaaaaa taatatgtga attttctgat atttactaat tatgaataaa atatttaagt
     5701 attaatgttt ttagtgagac tttaagacag ataatctcct attaaagata ctatatctta
     5761 gataaaataa attaaaacaa tataaaaaca taacaagatt acagaaagaa agctcacaat
     5821 aaaatgctga aaaatttatt ttaaggagga ataaagtatg aagtttcaag aaatgattaa
     5881 tagcccaggt ctttggattg tttctagttt tttagtaatt atttcagttg ttcaagcaat
     5941 cgtatttatg aaagaggcac taaaagaggc ttcaaatctt ggtattgaaa ggaaaggaat
     6001 taaagcagca attcgctcag ctagtgttac agccattgga ccttctctat ctcctgttat
     6061 tacattatta tcactggtag ctgtgattgg cgctcctacg acttggatga ggctctgtga
     6121 tgtcggagca gctagaacag agcttggagt aatatctctt acatccaatt tatctggggt
     6181 agaagtaggt agtgctgcat ttggagcaga agctttttcg tatgcactat gggggatggc
     6241 tttaaataac ttaggttggc tatttgttgt atttattttg ggtcatagaa tgcgtggaat
     6301 tgttgaaaag atgaacatga agtataatcc tacttgggtt aaaaaactac ttgcaggagc
     6361 tacagttgga ttatttgctt accttctttc aaatcaaata aaaacatttg aaataccaaa
     6421 acttacacca gcaattattt cagctatagt tatgctagta ttgacaactt tatttaaaaa
     6481 gaatcaacga ttacaagaat tatccttagg tattgccatg ttaattggta tgtttggtac
     6541 acagattata ttatcgtgat taaaacggat aagaggtgat aattatgtat gataaaaaga
     6601 tgataaaaat agggagaatt tctataggtc ttgcaattat tgcaaacttt attcccgcta
     6661 tctatgtagg tattcgcttt ggtcagatgc caatgctttc tgttatattt caaatttggg
     6721 ggttagtcgc tgcgacttat ggggttagtt ggattgttca acctatagct tattatccta
     6781 cactaggagc tccaggttct tatataggtt ggcttgcagg ttctgttgga gatatacgta
     6841 tgcctgcagc atcaatggca cagaaaattg caggtgtaga agcaggaact catgagggtg
     6901 aagttgttgg aacaattggt acatgttgtt caatctttgt atcagcttct atgattacca
     6961 tttttaccat tgtaggctat aaagtaattc ctttgttacc tgaatttgtt actaattcat
     7021 ttaattatat acttccagca ttatttggag caatttatgt tgatattgca cgtaaggata
     7081 ttcgagctgg tggatgtacg attgctgtag cgttagcaat tatgtacttt ggtgaaaaaa
     7141 ttggtatacc aggtggatta ttaacattgt ttattgtgtt aggtgggata cttatcacaa
     7201 gggtcttctt tgtaattgat aacaataaaa caaaagaata ggattgctta ttaaggagaa
     7261 agactagaat tatttgttga gaaaaaagaa taggattgtt tattaagaaa tatgaatata
     7321 aataagtctt gaaaggagaa aaagcatgtt tgatgttaaa attgtcaatg gaataatcgt
     7381 tgatggtaca ggaaattcaa gatataaaag tgatgtaggg attgtaggag acaaaatcat
     7441 ggctattgga gatttaagtc aaaaagaggc taaagagact atagacgcaa ctggaaaatt
     7501 tgtatcacct ggttttatag atttccatac tcattctgat ttatctcttg tgtatgataa
     7561 atacacaaga agccgtatcc atacaggtgt aacaacagat gttattgcaa actgtggtat
     7621 aggagttgct ccgataagag aagagaagaa gcaagagtta attgattatc ttggaactag
     7681 gataattggt acaattccaa caaaattaga gcttcattgg aatacaatgc aagaatactt
     7741 tgattactta actgaaaatt ctccagcagt caatgttgta gcttatgtag cacaaggacc
     7801 tgtacgtatc aatgaaatgg gattttcaaa ggaaccagct actttagagc aacttaaaaa
     7861 tatgaagttg gaagttagaa aagctatgga agctggatgt gtagctcttt catcaggatt
     7921 agtttattta ccaggagcat acacaaagaa agaagaaatg gctgaattat gtaaggaatt
     7981 gataccatac aatggatact atatatctca tattagagat gaaggtgatg aagaaatgga
     8041 agctcttgat gaagcaattt atatagctaa gactgcagga gttcctctac atgtttctca
     8101 tttaaaagtt atgggtcata agaattttgg aactattgat gaggtattta aaaagctaga
     8161 tgaagctgag gcagatggtt tggaagtaac ttttgattgt tacccatata cagctggaat
     8221 gacatctttg ggtgcacttt tacctccttg ggcttttgaa ggcggtgtag aaaatatggt
     8281 aaaacgatta gaagtacaag aaaatagaga cagaattata aaagagttgg aggaagggat
     8341 tcctggatgg caatgtttct accaattagc aggtgggtgg aacggtgttg tactagcctc
     8401 tgtaatgact gaagcaaata aatatgtaga gggtaaaact ttaatggagg tagccaaaat
     8461 caatggtgaa aatccatttg atacgttctt taggcttttg attgaagaaa aaagtaaaat
     8521 tcaagtagtt gttcatacac aaggtcaaga ggatacagat aaggttgttt gccatccaaa
     8581 gtcatgtata ggttctgata gtatggacct ttctacagaa ggtttacttt ctcttggaaa
     8641 gcctcatcct cgtgcatttg gtacttttgg acgaattttc tcttactatg ttagagaaaa
     8701 aggtatgttg acttttgagg aagcagttaa aaagataact tatctttcag caaaacgctt
     8761 aggcatttat aaagaaaggg gtctacttaa agaaaattat tttgctgaca ttgtggtatt
     8821 tgacccagat acaatagaag ataaagcgac ttatagtaat cctaaacagt atacagtggg
     8881 agtggaatat gtgttggtga atggtaaaat tgcattggca ggaggaaagc aaactgatgt
     8941 atgtgctgga cgtgtaatta aaaatcctct tagcatagca aaatagaata cattaagaac
     9001 ttttataaaa atagtctttc tttgaatatt aaggaaggct atttttgtta aattaataaa
     9061 gattactcta cttgtgtttt ctaaagaatt taactttaag tagaaaaaac aatatattaa
     9121 ttgtaaaatg taattaatat taatgaataa gatttaaata caaaaattta aatacaaaaa
     9181 tgtttcaaca gatagtcgta attaaaaaac ttaaagtaac tttttatatt aggtataatt
     9241 gattattcaa aattctatga atcaggagtc ctgtgccttt agtcatggta ggtttagaaa
     9301 atgttttaag agataatagt atcattagga aaggagagac gaaatgaaaa tactttatgt
     9361 aggaccaggt atggtaatcg ataaaatact agcagtaagt aaaaagaatt ttcctaatat
     9421 tgaagcagat tttcttagat atgatagata tattgaagta cctgatttat tggaaaaata
     9481 tagaggtaga gtggatgcag ttctttttac aggtaagtcg ccatttaaat tttttgaaaa
     9541 aagacaaaaa gattttgtat tgtctgatta tattcctaga catgaaacaa cattgtacag
     9601 agtgttgctt gaaattacat atttgcttaa attcgatatt agtagactta gtataggtac
     9661 ttatgataag gctatgatga agagattgta taaagaaatt ggagttgaat ttaaggatga
     9721 acatatgttt tttgcagagc aaaagtattt agaagaggac tatataaagt ttgtgcttga
     9781 atttcataaa tataattatc aaaataatga tgtatgttgt tgtattacag gtcttgaaga
     9841 ggcctatcat ataatgaaaa aagataatat tccagtagtt ttagccttgc cttctgagga
     9901 cgtaatggtg caaagtataa aaaacattca gatgcgttat attgcaaaga aaaacaatga
     9961 gaatcagatt attgttcttg ctattaaact gaacatgcct tcagaatatt cactaatgaa
    10021 ggaagatgag tacgcttatc tttcacaaag gattaagatt cttgataaac tataccattt
    10081 caatagccgt atagatggtg ttttggtaga gcagagtaga agtgaattta tgatttttac
    10141 aactaaaaaa atacttgagt tagaaacaaa gaaatacaga gatatttatt tgttggatat
    10201 gattcgtgaa gtttcagtta taaacactta tataggaatt ggttatggaa aaacagcaaa
    10261 tgaagctaaa tttaacgctt atgagagtat taagatggct caaagtcaaa aaaatgatgc
    10321 agcatatgta gtttttgaaa atggagaaat tatgggacca ctaaagccaa atcctactgt
    10381 caaagagaaa aatagttttg atgaacgttt ttatcaaatt gctacagaga cagggctaag
    10441 tgctaatact gtatataaag tattcaataa aataataaat agtggaaaaa ctgaatttac
    10501 atcaaaggaa ttagctacta tatgtggtgt aagtattaga actatggaca ggattatact
    10561 tagattgtgt gattctggtt attgtgaggt agtgagtgaa cagcttatga gcaagtatgg
    10621 tagacccagt agaatattac gttttaaacc ttttctgttg ttttaaatag atataagtca
    10681 aaaattaaat ttttatgata acattttctt tacaactttt tagatatatg ttaatattta
    10741 gaaaaatgca tatgtattca taaaataaac tcaaaacagc taaaaaatca ttaaaaagga
    10801 aatcgtatgc ataaaatgag aaagttaatt tataacttaa ataaatctgg gaggagataa
    10861 ttatgggaaa atatcaggat tcaaaaaaag ttgtaagaaa ttattttgaa gcattagaaa
    10921 atgctactgg ggatgaggtt gaaaatgtct taaagcaaca tatgaaatca gattataact
    10981 ggaaaggtgt gtatccattt cgtgaacaag aaggcactga aaatgtagca gatgtatttt
    11041 ggaagccttt aaaaaaatca ttgagtaata tgcaaagacg acaagatatt ttcattgcag
    11101 gaacaaatga gattgacaat agtgaatggg taatgagtat ggggcatttt atgggacttt
    11161 ttgataagga ttggcttggc attaaacata ctcgcaaaat gattagttta agatatgcag
    11221 aatttaactg tgttcaagat ggtaaaattg ctaaaactgg attatttgta gatataattg
    11281 ggtttatgat tcaagcagga gttaatccat tgccaccaca aacaggttca tattttgtat
    11341 atccagggcc aattgaccat aatggattac tttttgaaga tgcagatgaa gttgaaggag
    11401 taaaaacttt agcactagta aataaaatgg tagatgattt atctgaatta aatgaaagtg
    11461 gtgctatggg atgcccacca gaaatacttg aaaaatcttg ggctaaagat atgatttggt
    11521 atggtccagg tggaattggt gcttcttata ctatacctag atatcaagag caacaccagc
    11581 taccatttag aaataattta aaaggaaaga cttttaatgg gcatgtatgt agatttgcag
    11641 aaggtaattt tgcttgtttc tttggatggc ctaatctgac taatgtacca tgtggaggtt
    11701 ttttaggatt accaggtgga gaggttaaag cagatatgca agttgttgat gtttattatc
    11761 gtaagggcga taaacttcaa gaaaactggg tgttaattga tattccttat tggttgaaac
    11821 aacaagggct tgatattctt gagagaacta aaagtatttt taatgcttag ttatgcatac
    11881 gtattctaaa acaaaggggg atataaagtg gcatctacca acaaaaataa tgcaacaagt
    11941 aaagaggaag aaaaagaagt ttctacaagt gggcttgaat catgtacggt taaagaaaac
    12001 aaagctaaaa tgaatcaaac taattttagt aatataaatg aaaatcaaac aaatgagaat
    12061 aaaacgaaca catataaaag aaatatagat aaaggaaata tagataaagg gaatatagat
    12121 aaaacaaaca caaataaatc cgacataaat aaagttaaca tagatacagt ggatacagat
    12181 aaattaaata caaatactct tactgaaaaa aataaaaaag ttatatttaa gggggaagat
    12241 aatatgtcat ctacaaaaat ttactatgga gattcattag aagtaacgcc tgttggagta
    12301 atggattaca atgatttttc aaaacagaca aaaagggaac aggaaatacc tggatttgat
    12361 tctaagtata gagattttgt agattatatt atgaagatta cacataatat ctgggaagaa
    12421 aaaggtatag gtgttattta tgatacatat cacaataatg ttacaatgca ttgtggctct
    12481 tcaaatttag ttggtattaa agatgttatt tccaatactc ttcaaacatt acatgcgttt
    12541 cctgatagaa gattaattgg tcaaaatgta atatggtcta actttggtgc tgatggtttt
    12601 ttatcttctc accgtgtttt gtctacagca actaacttag gtgatagtaa ttttggacca
    12661 gcaacaggta gaaaaataaa ctttagaact gtaattgatt gtgccacaac taacaataga
    12721 atccatgaag aatggttggt tagagataat ttatggattg ttactcaatt aggattaaac
    12781 cctcaggaag tagcaaagag tatggcaaag gcaagtgaat ctaaagtgct tagtttacaa
    12841 tcaacttatg gtatctgtga atctatggat ggtcaattta tgccaactaa gtatcaagca
    12901 aaagatgatt ctgttggcga aatgatgctt gaaatgacaa gccgtattta taattataaa
    12961 tatataaatg aagttaaaaa atactatcat gataatgcag tagtacattt tatatgtgat
    13021 aaagatttaa atggctatga tgagattcaa ggaatgattg taagtttatt tgcatcaatt
    13081 ccaaatggaa gttatgaagt ggaaagagta acttgtaatc aaagagaaaa aaatgaaggt
    13141 tatgatgtat ctgtaagatg gagattacgt ggaataaatg aaggtatagg attttttgga
    13201 cagccttctg gaaagcatat agaagtaatg ggaatcaatc attatcatat actacaaggt
    13261 aaagtaaagg aggagtggat aacttttgat ggtatggatg tattaaaaca aatttatatg
    13321 ggagtagaag aataaagctg tttagagtat aaatagtttt gaaatatata gggaagtatt
    13381 gctttataaa atttaagtgg ggaatgtata tgaaaaatag atgtttaaac ttttagcaaa
    13441 attatgacta aatttaaaag ggggaattat aaaaatatga aaacaacggt tgaaatagaa
    13501 aatgatatca tattaggaaa agactattca aacctaaaaa gaggaattgc atttttttca
    13561 attgctttaa tatacttttt ttattgctac aattttatgg tgggtacttt tattaaacca
    13621 acaatgattt atgctttagc agatggggga tttggttttt cattaaaaca aacagaagaa
    13681 atatttgcag ttatgtcttt tggtacaatt ccaggtacat ttatttttgg ggtgatttct
    13741 acaaaaattg ggaagaagag gactttaatt agcgttgctt tactgattgg attgacaaca
    13801 tttataccaa tgttatctcc tacaaatatt atgttatgga aaatagcacg tttgtgtaca
    13861 ggagtagtgt tgggaggcgt atttggaaca gctatgcctt tagttgcaga tatgtttcca
    13921 agtaaatatc gtggtaagtt agctgctata ttaactgctt tattttcatt agcaatgatt
    13981 tttggtggga aagtatatgg cgttttaggt gatgcaaatt ggcaaatatt gatgtatact
    14041 gcgattatac cacctatagt tggagctatc ttagcaatct tctttgtgcc agatgatttg
    14101 gagtatacaa aggaattagt taaaaaggga aaagaaactg gtgaaaagat tagctatata
    14161 agtatgtata agggaaaata cttatggatt ggattgggaa cgattctttt atcaggtgca
    14221 aattttacag catattcagc attttcaaat aatgcaacta catacctagt gacaggaata
    14281 ggaatgtcag cagcagtggc tgagtctata tatagtttac aaggaattgg tcaattagta
    14341 ggatatttat tctggggttc aattgcagat aaatttggaa gaaaaatacc ttttataggt
    14401 atggcattag cagcagtatt tgtttttata tatacaaaat taggtggaga taatacaaca
    14461 acattctata tgatatcagt attactaggt gttgctgttg gatattctgg agcatgggga
    14521 gcatactaca cagagttgtt cccaagtaaa tatcgttcgt tgtcatctgg tatgtcattt
    14581 aatggaggaa ggattatatc tacgtttgca atacctgcta tagctggtac agcttctggt
    14641 actttaggta tgatgactat cttttacata tcaatcgcag tctttgtagc aggtgctatt
    14701 gtatggttat tcttaccgga gacgctaaat aataaaaaat aaaatactag gaatttattt
    14761 tgttacttag aaaggggtgg cttatgattt catcaattga tgtatgtatt ataataggat
    14821 atttgctatt aatgttagtt attggttatt attcaggaaa agataataaa aatcaagaag
    14881 attatttctt ggcaggtagg tcaatgccat ggattccaat tgctttatca gttgcagcta
    14941 ctatgattag tgcaaatggc tttataggtg gtcctggatg ggcatatgta gatggaatgt
    15001 atccagtaat ggttaatatt acagtacctt tagcaatatt ttttgcactg agcattacca
    15061 ccccagttat ctataaatta aaaataacct ctatatatga atatatggga cttcgtttag
    15121 gaaattattc aagaggatta actattattc aattttttat taattcattg attcaagcta
    15181 gttctatggt atatattcca gtgcttatta ttcaaatgat tactggctgg tcactttatg
    15241 ctttagtccc aatagttgta cttgtatcaa ttatatatac tctattaggt gggattaagg
    15301 cagttatatg gactgatagt attcaaatga tagtagtaat aagtgctgta tttatagtaa
    15361 ttattgtagc cttaaaagga atgaatctaa gtttctttga tacattacaa attgcacaac
    15421 agagtggaaa attaaataca tttgatttca gtagggatat ttcagtgaca aatacttttt
    15481 gggctacttt aattggtgga actgtaatgt ggataagata cttttgtttt gaccaatctc
    15541 aagtacaaag agttttaaca tctaaatctt taaaatgtgc aaaaaattct tttgtagtta
    15601 gtgcatttgt tatgaattta gtttactact ttatgctatt ggtaggagta attttatttg
    15661 ttttttatgg gggaaggaca tttgaaactt caaatgaaat aatgattact tttattttaa
    15721 atgaacttcc agtaggagcc attggaatta ttattgcagg tgtgtttgca gcagcaatgt
    15781 ctagtatcga ctctatatta aacagtatga caactgtttt tacgaaggat atttatgagt
    15841 tttatttcaa aaaagacaac aaagaatcat cattaaaagt tacaatgatt ataactgtag
    15901 ttataggagt tgttatgaca ggttttatta ttatgggatt tggaggaagc atcaaatcaa
    15961 ttcttgacct tgttggtaac tatatctcat actttgctgg accagctaca ggtgcatttg
    16021 tactagcaat gtttacatat aaagctaatg ataaaggagt atctattggt tttattgtag
    16081 ggttagtttt aggatttttt atttctaata aatataatgt gagttggttg tggaatccag
    16141 caataggtgc tacaataaca ttgatatttg gatatatttt tagtgtcatt ttaaagaaaa
    16201 atcataatgc agatgatatt aaaaaataca ctgcatttgg tatgagaaat caccttattt
    16261 ctcaaggaat ggataaagta gatggagtat ctatagtgcc attttcttta ggtaaacaag
    16321 aactaattgt attagctttt ttcattatcc aatatattat attatttttg atacaatttt
    16381 aagaagaaat actagatatt taaggagaaa tactaaatga atcaaaagaa agttcattat
    16441 aataaatcgg ctacctcaaa agatgttgca agattggcag gagtatctca atcatctgtt
    16501 tcaagagcat ttggtagtgc aaatggaaag ggcgtaaaac ctgaagtaag agaaagaatt
    16561 tttcgtgtag caaacgaaat aggatatgtt cctaatttgg tagcacgggg aatgattagt
    16621 ggaaaaacta atgttatagg attgatagtt ggtgatagtc taggtccatt ttacaataga
    16681 attatcaatt tatttgtaga aaaaattcaa gagataggta aacagtgtct cgtttttaaa
    16741 gttcctagac aacaaagtat agatagtata atttcaaaag taattcagtt tcaagtagaa
    16801 gctgtgatta ttacagcttc ggccatgaat aaggtgatgg ctgagacttg tgaagaaaac
    16861 aatattcctg tgattctttt taatcgtttt atacctggta taaaaataag tacagtctat
    16921 gtagacccaa ttgaaggtgg gggaatggct gctgaatatc tgcttaagaa aggtcataag
    16981 aatataggat atattcaatt tacgagagaa acaagtgaag aaatggaaaa gaaaattgga
    17041 ttttattcta agttaagaca aagtgggatt cataacctta aagaagaatc tgcaaactat
    17101 gattatgatt ctggatatga agcaggtaag agaatgttag cattatcaaa tcctccaaca
    17161 gcaatttttt gcacaagtga cttgatagct attggtgtaa tggatgctgc aaggtttgag
    17221 tacaagttga gggtgccaga ggatttatca gtgataggat atgatgatat tcaaatggct
    17281 tcatggaaga gttataattt aacgacgatt agacagccac tagatttgtt gattgaaaaa
    17341 acaattaaca tacttaagtc cttattaaat gaagaaaatc cagagtcagt tgttgaaatg
    17401 ttaaaacctg aattgattga aagaggttct acactttaag tggtagatat ttaattaagt
    17461 gatagatatt taattaagtg gtagatattt aattaagtgg tagatattta atcaagtgat
    17521 agatacctaa ttaagttgta gatatctgat aagaaatttt taagttttca atcgttctaa
    17581 attgtgagta taaaaatcta ctaaatttag ttatgtaaaa tataaattat aagtgtagaa
    17641 actaggctac tagcttttat accacttcaa acattactgg aggtagttaa gtttacagca
    17701 gtttagtttt atgtagatat aatattctgt aaatagacaa aattaaaata tgtaattaaa
    17761 atatgtaagt gtctcaaaat gaaattttta gtttatgagg cacttttttg tataaaatca
    17821 aatgtatttt tataacttta acaataaaaa gaggcttatc tctattttga gacagcctca
    17881 aatttttaaa actatattag tttacagctt cttttcctat caaatctttt aactcttcat
    17941 gagtcatagt ttctttttca aataagaatt tagaaacaga atgtaaatct tcaagattat
    18001 cctttaacat ctctaaagtc tctttataac aaatttcaac tatacgattt gcttcctttt
    18061 gaaccttatc acataagaaa gtcttatcat ttccatcaat agtcataaat cctaagttac
    18121 tcataccata ttcacaaacc atttggttag ctatttcagt gactttcttt aagtcgtcct
    18181 ttgcaccagt agatttatga ttaaatatta attcttctga agcctttcca gcaagtaata
    18241 tttttatttt tccaatcaac tcatccttag tataaatata tctatcttca tcaggtaatt
    18301 gaagaacata acctaatgct tgtcctctag gaactataga tattttttgt ataggacaaa
    18361 ttcctactat atcacttaca agagcatgtc cagcttcatg atatgctact atttttttct
    18421 ctttttcaac caatgcagag tttttagatt ctagccctgc aataactctt tcaagtgcct
    18481 tgtcaaaatg ttctgatgta atacactcac tgtcatctct aactgcaaat atagctgctt
    18541 catttgctat atttgaaaga tgagccccat tgaaaccatg agttttttta gctaaaagtt
    18601 ctagatttac agatttgtct ataggtttgt catctgtatg tacctttaga atttcaaatc
    18661 tagtgtgata gtttggtgca cctatatgaa tgtgtctgtc aaatcttcct ggtctaagta
    18721 aagcttcatc taataagtca agtctattgg tagcacctat tattaataca ttggaatctt
    18781 tattaaatcc atccatttca actaaaagtt ggtttagtgt ttggtctttt tcgttgttac
    18841 tttcaagatg tctctttgct cctacagcat ctatttcgtc tataaatatt atacttggag
    18901 cttcttttct agctttttca aatagagttc taactctttt tgctcccaca cctacatatt
    18961 tttcaacgaa ctctgaacca gtaacattga aaaatgatga gtttgtttca ccagctacag
    19021 cagatgcaag tagggtttta cctgttcctg gaggaccata aaataatact cctttaggta
    19081 tttttgcacc cattttttga tatttttgtg gtgacttcat aaaatcgact atttcaaata
    19141 gttcttcttt tacttcgtct aatccagcaa cgtctctaaa tgtagtcttt ggttttgtag
    19201 aaagtgaatc atctgtttga ttatctcttt ccatttttgt ctgtgcaaag acaggagctg
    19261 gattgttgat tttcttaaaa aagttgttta gcattttcat attcacacct caggtaatta
    19321 attattgtta atcaatttta tattttccat atttactatt ttttattatt tatttttcat
    19381 ggaaaaaata tacatgttat ctaaataaaa ataaatttgt aagatgtatg aaaaaatgaa
    19441 tttatgtata tagagatttc tacttatgta ttgaataaag tattacaaat tataaattat
    19501 gtattgatta tatattgagt aaagtattat aaagcatgta ttgattaagt atttattaag
    19561 tattgaataa aatattacaa atttagttga aatgaaaatg ataaaaaatg ttgtactata
    19621 ttttacaaat catataaata gagaaattgt tgtagcacaa agtagtaggt agtatattag
    19681 aatataatta taggatttgt tgtgtagtat agtagcatat tagaatataa tataggattt
    19741 gttatgtagt atagtagcat attagaatat aatataggat ttgttatgta gtatagtagc
    19801 atattagaat ataatatagg atttgttatg tagtatagta gcatattaga atataatgta
    19861 ggacttgtta tgtagtatag taacatatta gaatataatg taggatttgt tatgtagtat
    19921 agtagcatat tagaatataa tgtaggactt gttatgtagt atagtaacat attagaatat
    19981 aatgtaggat ttgttatgta gtataatagt atattagagt acaatataga atttgttatg
    20041 tagtatagta gtatattaga atacaatata gaatttgttg ggtagtatag tgttatatta
    20101 gaatacaata taggatttgt tatgtagaat atatagagtc atgtagaata tacatatata
    20161 aaaggatttt gggtataaat ttaaaaatta atagcaaaat gagtagtata gacatataat
    20221 tagtagtagg aagtaattaa atttttccta aacaaaaaaa atagttgcaa ataatttgat
    20281 taagtgatat agtaaataag gtaagaataa aacaaagaag aagtccgctt ctcaccttac
    20341 gccggaggtt agtaaggtaa atataagtta aagcttaatt ttaatttaag tttgtttaaa
    20401 tttggtaact tatattgcgg atgattacgt catccgcttt ttattttata aaaattttgg
    20461 aggtgtccta caattagcaa agaattagca atcaatgaac aaataaaaga taaggaaata
    20521 agagtccttt caccaacagg tgaacaactt ggagtaatgc ctactaaaga agctcaagca
    20581 atggctaata gcaaaaactt agatttggtt caaatctcgc cgaatgcaaa tccaccagta
    20641 tgtaagataa tggattatgg aaagtttaga tatgagcaag cgagaaaaga gaaagaagct
    20701 aagaaaaaac aaaaaactat agttgtaaaa gaagtaagac ttagaccagg tattgaacaa
    20761 aatgatttaa atacgaaagc taataatgct ataaagttcc ttaaaaaagg ggataaagtc
    20821 aaagttgaac ttagatttag aggaagagaa ttaggacata aagacatagg taaagaagtt
    20881 atgcttaagt ttttagatat aataaaagag tttggagaac caacaaaagc ccctgcattt
    20941 gagggtaata atatggttgt aattatagat ccaaaaaaat agatgattaa ctgagaggag
    21001 gaatttgtca tgcctaaaat gaaaactcat agaggtgcag caaagagatt aaagaaaaca
    21061 ggaactggaa agttaaagag agctaaagct tttaaaaaac atatattaac taaaaaatct
    21121 gcaaaaacta aaatgaactt aagaaaatca actttagtaa gtgatggaga tgctaagaga
    21181 atagcacaat tattaccata ctaagataca gattgtaaat aataactata gaagagggat
    21241 ataaaaggag gtcataacga tggcaagagt taaaaaagct atgaacgctc gtaaaaagca
    21301 taagaaaata ttaaaacttg caaaaggatt cagaggatct agaagcaaat tatatagacc
    21361 agcaaacaca ttcgtaatga aagcattaaa aaatgcttat ataggaagaa agttaaagaa
    21421 gagagacttc agaaaacttt ggatacaaag aataaatgca gctgctagaa tgaatggaat
    21481 atcttattca agattaatga atggattaaa attatctggt gttgaagtta acagaaaaat
    21541 gttatctgaa atggctatac aagacccaga aggatttgca aaattagcag aagttgctaa
    21601 agcaaaatta gcttagtatt gaatcatgag atgtaaagtc tttgagttat ataaataatt
    21661 caaggacttt tttatttttt gaaaaatact tattagtgtc atgtacaacc aattttataa
    21721 tgataaataa aataagcaat acaatagaat tttatgagat ttattataag aattgttaca
    21781 attatttatg atagctataa aaaatcatag taaaaatgat actgatgtat gttgatatat
    21841 gtataaagtt tccaatcaat cttgaattaa tattatcaac atgataatat tatcttatta
    21901 ataatataaa taagggggag ataatatgaa tgaaaaacta atggattgtt ttgtaaaccc
    21961 aattaaatgc aagttattga ttgaaatttt ttcaaataat cgaactacag ctaaacaatt
    22021 aggagaaaaa tttcaagata tatcaaaggc aacactttat cgttacctta ataaaatgtt
    22081 gaaagatgat attataaaag tagttgaaga aaataaaata aggggaactg ttgaaaaagt
    22141 atatgctatg aagttagata tagctgatga tgtgaacaaa attatagatg agaactctgg
    22201 agaagaatat gctcaactgt ttactcaata tatgatggga tttttaagag aattttatga
    22261 atacgctgaa agaaaggaaa aggatatcct aaaagatggt tcaggatttt ctgtctgtcc
    22321 agtatatgct agtattgatg agatagttga agtgagtaaa aaaattgcta gtatactaga
    22381 acctctaaga aataactcgc acgaagaagg cagaagaatg cattctatag gagtgataat
    22441 cactccacct aaagaggatg aagggaaata aatctgattt acatgaggta gagccaattt
    22501 acacagaaaa tcgttttatg atttacatat gtatccagag caaagtatct ctgcttggat
    22561 tgtacttcat tgtaccattt catccaatga cttggagtgg tacaatgaag ttttttaatt
    22621 tttcatatta atgctaaaga aatgaacttt agaccacata tgcaattagg ttgcattata
    22681 caattagacc acatatacaa aataaaaatc agtattttta tagcagataa attgactgtc
    22741 attcttctta aaaatcatct attagttatt gttagcatat tgaaagaaat tatagtaatc
    22801 tattgaataa atgaatattg cctataatca tataaactgc tatagtttaa aataaagcag
    22861 gacgttaaat tttatagtaa tctaaaaatt taagaggggg attttatgaa aataaaattt
    22921 gttattatgc cattggtgat atttttaatg gtattatttg tggggtgtca aagtacaaaa
    22981 gatacagaag ttaaagcaaa agatacagaa attaaaatat tagggacagg tgatttacat
    23041 tcaattttga cagactctat ggtttcgtat gtaaatgagg aaagggaaaa gaataaaaat
    23101 ctgcttatgg tagatgcggg agatttctat ggtacacaaa gtagagaaat gtgggaatgg
    23161 tcttctggaa aaaagttaat taatattaaa agaaatggta gagcagagta tgatgacata
    23221 attaagagta gtaaagatga agtacctata gttaaagata tggcaaagtt gaaatatgat
    23281 gctgtagttt tgggagataa tgaatttgtt tcaaatgata agcaaagtct tgataaactg
    23341 gtttctgatt ttaaaaataa taatatgcca ttggtatcag caaatatata tgaacaatct
    23401 ggagaaaatt atgtacaacc atatgtaatg aaaaatatta agacagatga gggcaatgta
    23461 aaagttggaa tactaggtct tactataaaa gaagtagggg aaacccttgg tcttgaggat
    23521 tttgaaaagg ataaaaaagc tagagagctt ggagaacaag ctgattacaa aggaaaatta
    23581 tatgcaaatg atttagtaga agatgcaaag aaatggataa aagttatgga aaaagaaagt
    23641 ccagacataa tagttgcagt tgtacactca ggggaagaac ctaaaacaga tagaaatcca
    23701 ggaaatagaa taaaagagtt agcaactaca gtggatggaa tagatgcaat tgtagctggt
    23761 catactcatg aaaaaataga tgaacacaaa tataaaaata aatctggaga tgaagtaatt
    23821 gttacacaac caggttggca tggagataga gtatcagaga ttaatttcaa attaaataaa
    23881 gagaatggaa agtgggacat aaaggaaaag tctagtaaat taaaaataat tgataaagaa
    23941 gtaagtatag ttgctactgc agatttacat tcacatttct ctgataaatt aacagttgac
    24001 cttgttaatg aacgtagtaa cccaattgaa cctgttgtag tagatgcagg cgacttctta
    24061 gaccctcaaa cagatgaaat gactcaatgg tataaagagt ggaaaagtat aagagataat
    24121 aatagtgata aaacgattag tagatgccca atggtcatgg atatgaatca gggaatgtat
    24181 gatgcagtag tacttggaaa tcatgaattt gtatctgaaa aagatgaatt ttggtcagat
    24241 gaacgccttt tagatgctgt tatagaggat tttgaacagg tggcaatttc tgtgttatcg
    24301 gcaaatatat ataggcaatc tggtaaaaat tatgttaaac catatattat aaaagatgtg
    24361 gagacgagtg aaggtaatgt aaaagtagga atattgggac ttactataaa agaagtaggt
    24421 aaaggtctta aaaatgtaaa cttacaagag caatttcaat ataaggataa attgtatgca
    24481 aatgatttag tggaagatgc aaagaaatgg gtaaaagtta tgaaaaagaa aaaaccagat
    24541 ataatagttg cagttgtaca ttcaggagaa gaaccaaaaa atccaaaaca tccaggaaat
    24601 agaataaaag aactagcaac tacagtagat ggaatagatg caattgttgc tagtcatact
    24661 catgaaaaaa tagatgagca tgaatataaa aataagtctg gagaaaaagt tatagtgaca
    24721 caaccaggtg agcatggtaa atattattct aaaattacct ttaaagtaaa taaagaaaag
    24781 ggttcgtgga ttattaatga taaattcagt aaaacaattg aggttgaata actttataaa
    24841 atttatagat aaagtaaatt atctgatatt gacatgatat ataagataaa gtttctaata
    24901 ttagtataat gcataatgtg aaatatttta ataataagag aataaacaag acaaataaaa
    24961 atattttaac atgtaagata tagtatgaac tattatacta atgcttactt tataatttga
    25021 acatgttaga ataagtctta tttgaaaatt ttagtgtatt agagtaagta ttattttacc
    25081 agtaaaaaat attgagaact atatgtagat ttgcttaaaa aggaatttac atatagttct
    25141 tttcgtataa taaatagtac aatcttatat ggtaaagata aagtgtgata ttaaatttta
    25201 ttatcatcca aaatctaagg aggagtctct tatgaaaata aaatttatta tagtagcatc
    25261 aataatattt ttaatagtat tacttgtggg gtgtcaaagt actaaagaca cagaaatcaa
    25321 tgtactcgcc acaagtgatt tacattcaat tattccagat aatttaattt cctatgtaga
    25381 agaggagaga aaatatgatg agaatctact tatggtagat gcaggagatt tttttgacat
    25441 gcaaagtggt gagatgaata agtggtttac tggtcaaaaa ttagtaagat ttaaagatgg
    25501 gataccagag tacaaaaaaa tagctgaacc acgtgaagga gaagttccat tggctaaaaa
    25561 aatggcaaag ctgaagtatg atgcagttac atttgggaat catgaatttg tatctaatga
    25621 caagcagagc cttgataaat tggtttctga ttttaaaaat aacaatatac cattagtatc
    25681 agcaaacgta tatgaacaat ctggagaaaa ctatgtaaag ccatatgtaa tgaaaaatat
    25741 aaatactgac aagggaactg taaaggttgg tatacttggt ctgactataa aagaagtagg
    25801 ggaacgttca aggtttaaaa gttttgaaca agataaaaag gctagagaac ttggggaaca
    25861 acctcaatac aaagggaaat tatatgcaaa tgatttagta gaagatgcaa ataagtgggt
    25921 aaaggttatg gaaaaaaaag aaaagccaga tataatagtt gccattgtac attcaggtga
    25981 agagccaaaa aatcctaaaa atccaggaaa tagaataaaa gaactagcaa caactgtaga
    26041 gggaatagat gctattgtag caggtcatac acatgaaaaa atagaacagc atacatataa
    26101 aaataattct ggtgaagaag taatagtaac acagcctgga gctcatggta atagtatatc
    26161 aaagattaat tttaagttgg ataagaagaa tgataagtgg tttataaaag acaaatatag
    26221 tgaattaaag gtttttggaa aggaagtaaa tataattaca acttctggtc tgaatccaaa
    26281 attttcagat gaaatggcag ttaatttgtt taatgaaaga gatagagatg ttcaacctat
    26341 atttatagat actggagatt ttttaaatac taatacaaaa gaaatgacta agtgggctaa
    26401 agagtggcaa tacaatgaaa ataaaggcat ctataaaaaa ataaatgaat ggccaattgt
    26461 atatcttggt tatgatgctg tagtacttgg tagccatgaa tttacagagg ataaagagac
    26521 ttttgaggaa aaaaaatcta cattggatta tattatagaa aactttgaag aaatgaagat
    26581 accagtatta tcagctaata tatatgatga atctggagaa aattatgtaa aaccttatat
    26641 aattcataat gtagaaacta gggaaggaaa tataaaggtt ggagtattag gtcttactac
    26701 tactgataag gatgaagaag acttaagtaa ctcaagctta agcaaagact caaagacttc
    26761 gaaaattcct gaagaaacag gaaagttata tactaataat ctagtaaaag atgcaagcga
    26821 atgggtaaaa gttatgcaaa aggaaagtcc tgatgtgatt gttgcagttg tacattcaga
    26881 taataatagt actctaaaaa atccaagtag tgaagtcaaa aaacttgcaa tgtcagtaga
    26941 tggaatagat gctattgttg taggtcatac gaaaaataag gtagaagaac atatttacaa
    27001 aaataagtct ggggatgagg ttatagtaac acaatctgga gaggattgtt attcaaaaat
    27061 aagtcttgaa ctaagaaaag aaaatggcaa gtggaatatc ataaacaaat atagtaaagc
    27121 aataaaaatg aagtgaattt attgatatat aaaccattat taatactgat tctacaatat
    27181 aattaacact gatttttata atataataaa tactgattct ataatataat taacactact
    27241 ttttataatg tcatcaacac tgattctata atataattaa tactactttt ttaaatataa
    27301 tcaatactga ttccataata taattaacac tactttttta aatataatca atactgattc
    27361 tacaatatta ttaatactac tttttataat ataatcaaca ctacttttta caatataatc
    27421 aatactgatt ctataatata attaacacta ctttttaaat ataatcaata tcgattctat
    27481 aa
//
LOCUS       DAFAZV010000056        26848 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFAZV010000056 DAFAZV010000000
VERSION     DAFAZV010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 26848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26848
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.056"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            456..1190
                     /locus_tag="KOU88_003265"
     CDS             456..1190
                     /locus_tag="KOU88_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3213119.1"
                     /translation="MNLAKGLDVLKISSNVFGEDKVMYIPVIYTEDDATLIDTGLPGQ
                     GDLIIDALNKSNTSFDRLKNIIITHHDIDHIGNINYLREKSKNNIKVYAYKSEVSYIT
                     GEETPFKLYMLEQMVDKIDDKMLSMLNVMGLGFKSSYTKVDVSLDNHEKLNLGEEIEV
                     IHTGGHTRGHICLYLKESKVLIAGDLLQVENGELKPVDVMYSNKQELKDAIKNISNYN
                     IETIVFSHGGLYQRNIIGTLKNLIIE"
     gene            2529..3785
                     /locus_tag="KOU88_003266"
     CDS             2529..3785
                     /locus_tag="KOU88_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBK3213120.1"
                     /translation="MIEKFKTLIWIKMIIRIKSVYKTYGGLFFLGLIGIPVGAIIGLI
                     DTIFGTVLLKVTDIRETYPMYLIPFLAVVGVVIAYCYFKFGGKSSKGMNLIFEVGHGE
                     EEIIPLRLVPFIISGTWLTHLFGGSAGREGVAVQIGATFSHWVGKRLPIKNASSIFLV
                     TGMAAGFAGLFETPIAAILFAMEVLVAGSLEYQSLFPAFTASFTASAVSKALGLEKFS
                     FALSSEVVFDLSIFWKLIVLGIIFGMVGGAFAWCLKLSKRKIGNRLKNPMIRIAIIGV
                     CLSVLFLLFYKGRYSGLGTNLIQNSFYGGEIYSFDWLLKFILTILTLSAGFQGGEVTP
                     LFSIGASLGVLLAGFFNLPIELVAALGYASVFGSATNTFFAPVFIGAEVFGYSYLPYF
                     FVVCAISYIFNMDKSIYSLQKISTKQ"
     gene            3848..5041
                     /locus_tag="KOU88_003267"
     CDS             3848..5041
                     /locus_tag="KOU88_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBK3213121.1"
                     /translation="MLTSLALIFLLGMASGGIFKRIKLPNLLGMLLTGIILGPYVLNL
                     IDNSILDISSDLRKIALIIILTRAGLSLDINDLKKVGRPAVLMCFIPATFEIIGMIVL
                     APKLLGVSILEAAVMGAVVGAVSPAIIVPKMLKLMEEGYGTEKSIPQMLLAGTSIDDI
                     FVIVMFTVFTGLAQGNSISAISFLQIPVSIILGVIAGAVIGICLAVFFKKVHMRDSAK
                     GVLLLSISFLMISLETALEGIVPFSGLLAVMSIGIFLQIKYRVVARRLSIKYSKLWVG
                     AEILLFVLVGATVDISYAFKAGIGAVILIFGVLLFRMVGVFFCLIKTNLTIKERLFCM
                     IGYIPKATVQAAIGGVPLAMGMASGQLILTLAVLAILITAPLGAFGIDVTYKKLLTSV
                     KGESK"
     gene            5242..5622
                     /locus_tag="KOU88_003268"
     CDS             5242..5622
                     /locus_tag="KOU88_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213122.1"
                     /translation="MCLKKLSKLELVIMKFIWNLDIKTNSYEIIDYMKEEHNLPEKVA
                     LKTLSKLSKKRFLYVQETGKCMYYTVAIKEKAYLEFISRNVQNLLKNNFIRNLLVSFH
                     EEELTEEKIKSLENWVVNWEEAYV"
     gene            6529..7083
                     /gene="tcdR"
                     /locus_tag="KOU88_003269"
     CDS             6529..7083
                     /gene="tcdR"
                     /locus_tag="KOU88_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin sigma factor TcdR"
                     /protein_id="HBK3213123.1"
                     /translation="MQKSFYELIVLARNNSVDDLQEILFMFKPLVKKLSRVLHYEEGE
                     TDLIIFFIELIKNIKLSSFSEKSDAIIVKYIHKSLLNKTFELSRRYSKMKFNFVEFDE
                     NILNMKNNYQSKSVFEEDICFFEYILKELSGIQRKVIFYKYLKGYSDREISVKLKISR
                     QAVNKAKNRAFKKIKKDYENYFNL"
     gene            7401..14501
                     /gene="tcdB"
                     /locus_tag="KOU88_003270"
                     /gene_synonym="toxB"
     CDS             7401..14501
                     /gene="tcdB"
                     /locus_tag="KOU88_003270"
                     /gene_synonym="toxB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_074049122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdB"
                     /protein_id="HBK3213124.1"
                     /translation="MSLVNRKQLEKMANVRFRTQEDEYVAILDALEEYHNMSENTVVE
                     KYLKLKDINSLTDIYIDTYKKSGRNKALKKFKEYLVTEVLELKNNNLTPVEKNLHFVW
                     IGGQINDTAINYINQWKDVNSDYNVNVFYDSNAFLINTLKKTVVESAINDTLESFREN
                     LNDPRFDYNKFFRKRMEIIYDKQKNFINYYKAQREENPELIIDDIVKTYLSNEYSKEI
                     DELNTYIEESLNKITQNSGNDVRNFEEFKNGESFNLYEQELVERWNLAAASDILRISA
                     LKEIGGMYLDVDMLPGIQPDLFESIEKPSSVTVDFWEMTKLEAIMKYKEYIPEYTSEH
                     FDMLDEEVQSSFESVLASKSDKSEIFSSLGDMEASPLEVKIAFNSKGIINQGLISVKD
                     SYCSNLIVKQIENRYKILNNSLNPAISEDNDFNTTTNTFIDSIMAEANADNGRFMMEL
                     GKYLRVGFFPDVKTTINLSGPEAYAAAYQDLLMFKEGSMNIHLIEADLRNFEISKTNI
                     SQSTEQEMASLWSFDDARAKAQFEEYKRNYFEGSLGEDDNLDFSQNIVVDKEYLLEKI
                     SSLARSSERGYIHYIVQLQGDKISYEAACNLFAKTPYDSVLFQKNIEDSEIAYYYNPG
                     DGEIQEIDKYKIPSIISDRPKIKLTFIGHGKDEFNTDIFAGFDVDSLSTEIEAAIDLA
                     KEDISPKSIEINLLGCNMFSYSINVEETYPGKLLLKVKDKISELMPSISQDSIIVSAN
                     QYEVRINSEGRRELLDHSGEWINKEESIIKDISSKEYISFNPKENKITVKSKNLPELS
                     TLLQEIRNNSNSSDIELEEKVMLTECEINVISNIDTQIVEERIEEAKNLTSDSINYIK
                     DEFKLIESISDALCDLKQQNELEDSHFISFEDISETDEGFSIRFINKETGESIFVETE
                     KTIFSEYANHITEEISKIKGTIFDTVNGKLVKKVNLDTTHEVNTLNAAFFIQSLIEYN
                     SSKESLSNLSVAMKVQVYAQLFSTGLNTITDAAKVVELVSTALDETIDLLPTLSEGLP
                     IIATIIDGVSLGAAIKELSETSDPLLRQEIEAKIGIMAVNLTTATTAIITSSLGVASG
                     FSILLVPLAGISAGIPSLVNNELVLRDKATKVVDYFKHVSLVETEGVFTLLDDKIMMP
                     QDDLVISEIDFNNNSIVLGKCEIWRMEGGSGHTVTDDIDHFFSAPSITYREPHLSIYD
                     VLEVQKEELDLSKDLMVLPNAPNRVFAWETGWTPGLRSLENDGTKLLDRIRDNYEGEF
                     YWRYFAFIADALITTLKPRYEDTNIRINLDSNTRSFIVPIITTEYIREKLSYSFYGSG
                     GTYALSLSQYNMGINIELSESDVWIIDVDNVVRDVTIESDKIKKGDLIEGILSTLSIE
                     ENKIILNSHEINFSGEVNGSNGFVSLTFSILEGINAIIEVDLLSKSYKLLISGELKIL
                     MLNSNHIQQKIDYIGFNSELQKNIPYSFVDSEGKENGFINGSTKEGLFVSELPDVVLI
                     SKVYMDDSKPSFGYYSNNLKDVKVITKDNVNILTGYYLKDDIKISLSLTLQDEKTIKL
                     NSVHLDESGVAEILKFMNRKGNTNTSDSLMSFLESMNIKSIFVNFLQSNIKFILDANF
                     IISGTTSIGQFEFICDENDNIQPYFIKFNTLETNYTLYVGNRQNMIVEPNYDLDDSGD
                     ISSTVINFSQKYLYGIDSCVNKVVISPNIYTDEINITPVYETNNTYPEVIVLDANYIN
                     EKINVNINDLSIRYVWSNDGNDFILMSTSEENKVSQVKIRFVNVFKDKTLANKLSFNF
                     SDKQDVPVSEIILSFTPSYYEDGLIGYDLGLVSLYNEKFYINNFGMMVSGLIYINDSL
                     YYFKPPVNNLITGFVTVGDDKYYFNPINGGAASIGETIIDDKNYYFNQSGVLQTGVFS
                     TEDGFKYFAPANTLDENLEGEAIDFTGKLIIDENIYYFDDNYRGAVEWKELDGEMHYF
                     SPETGKAFKGLNQIGDYKYYFNSDGVMQKGFVSINDNKHYFDDSGVMKVGYTEIDGKH
                     FYFAENGEMQIGVFNTEDGFKYFAHHNEDLGNEEGEEISYSGILNFNNKIYYFDDSFT
                     AVVGWKDLEDGSKYYFDEDTAEAYIGLSLINDGQYYFNDDGIMQVGFVTINDKVFYFS
                     DSGIIESGVQNIDDNYFYIDDNGIVQIGVFDTSDGYKYFAPANTVNDNIYGQAVEYSG
                     LVRVGEDVYYFGETYTIETGWIYDMENESDKYYFNPETKKACKGINLIDDIKYYFDEK
                     GIMRTGLISFENNNYYFNENGEMQFGYINIEDKMFYFGEDGVMQIGVFNTPDGFKYFA
                     HQNTLDENFEGESINYTGWLDLDEKRYYFTDEYIAATGSVIIDGEEYYFDPDTAQLVI
                     SE"
     gene            14623..15123
                     /gene="tcdE"
                     /locus_tag="KOU88_003271"
     CDS             14623..15123
                     /gene="tcdE"
                     /locus_tag="KOU88_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like glycosylating toxin export protein
                     TcdE"
                     /protein_id="HBK3213125.1"
                     /translation="MHSSSPFYISNGNKIFFYINLGGVMNMTISFLSEHIFIKLVILT
                     ISFDTLLGCLSAIKSRKFNSSFGIDGGIRKVAMIACIFFLSVVDILTKFNFLFMLPQD
                     CINFLRLKHLGISEFFSILFILYESVSILKNMCLCGLPVPKRLKEKIAILLDAMTDEM
                     NAKDEK"
     gene            15452..15634
                     /locus_tag="KOU88_003272"
     CDS             15452..15634
                     /locus_tag="KOU88_003272"
                     /inference="COORDINATES: protein motif:HMM:NF022413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213126.1"
                     /translation="MRDEGQNDIENKYQTLINDLIDSLKVIGKIYKEIKTLKKYKICL
                     QITIRQSPYLIEESIN"
     gene            15851..23983
                     /gene="tcdA"
                     /locus_tag="KOU88_003273"
                     /gene_synonym="toxA"
     CDS             15851..23983
                     /gene="tcdA"
                     /locus_tag="KOU88_003273"
                     /gene_synonym="toxA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105161403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin TcdA"
                     /protein_id="HBK3213127.1"
                     /translation="MSLISKEELIKLAYSIRPRENEYKTILTNLDEYNKLTTNNNENK
                     YLQLKKLNESIDVFMNKYKTSSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWI
                     GGEVSDIALEYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEI
                     QNPQFDNMKFYKKRMEFIYDRQKRFINYYKSQINKPTVPTIDDIIKSHLVSEYNRDET
                     VLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNRGNLAAASDIVRLLAL
                     KNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRWEMIKLEAIMKYKKYINNYTSENF
                     DKLDQQLKDNFKLIIESKSEKSEIFSKLENLNVSDLEIKIAFALGSVINQALISKQGS
                     YLTNLVIEQVKNRYQFLNQHLNPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIA
                     PYLQVGFMPEARSTISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLS
                     QLTEQEINSLWSFDQASAKYQFEKYVRDYTGGSLSEDNGVDFNKNTALDKNYLLNNKI
                     PSNNVEEAGSKNYVHYIIQLQGDDISYEATCNLFSKNPKNSIIIQRNMNESAKSYFLS
                     DDGESILELNKYRIPERLKNKEKVKVTFIGHGKDEFNTSEFARLSVDSLSNEISSFLD
                     TIKLDISPKNVEVNLLGCNMFSYDFNVEETYPGKLLLSIMDKITSTLPDVNKNSITIG
                     ANQYEVRINSEGRKELLAHSGKWINKEEAIMSDLSSKEYIFFDSIDNKLKAKSKNIPG
                     LASISEDIKTLLLDASVSPDTKFILNNLKLNIESSIGDYIYYEKLEPVKNIIHNSIDD
                     LIDEFNLLENVSDELYELKKLNNLDEKYLISFEDISKNNSTYSVRFINKSNGESVYVE
                     TEKEIFSKYSEHITKEISTIKNSIITDVNGNLLDNIQLDHTSQVNTLNAAFFIQSLID
                     YSSNKDVLNDLSTSVKVQLYAQLFSTGLNTIYDSIQLVNLISNAVNDTINVLPTITEG
                     IPIVSTILDGINLGAAIKELLDEHDPLLKKELEAKVGVLAINMSLSIAATVASIVGIG
                     AEVTIFLLPIAGISAGIPSLVNNELILHDKATSVVNYFNHLSESKKYGPLKTEDDKIL
                     VPIDDLVISEIDFNNNSIKLGTCNILAMEGGSGHTVTGNIDHFFSSPSISSHIPSLSI
                     YSAIGIETENLDFSKKIMMLPNAPSRVFWWETGAVPGLRSLENDGTRLLDSIRDLYPG
                     KFYWRFYAFFDYAITTLKPVYEDTNIKIKLDKDTRNFIMPTITTNEIRNKLSYSFDGA
                     GGTYSLLLSSYPISTNINLSKDDLWIFNIDNEVREISIENGTIKKGKLIKDVLSKIDI
                     NKNKLIIGNQTIDFSGDIDNKDRYIFLTCELDDKISLIIEINLVAKSYSLLLSGDKNY
                     LISNLSNTIEKINTLGLDSKNIAYNYTDESNNKYFGAISKTSQKSIIHYKKDSKNILE
                     FYNDSTLEFNSKDFIAEDINVFMKDDINTITGKYYVDNNTDKSIDFSISLVSKNQVKV
                     NGLYLNESVYSSYLDFVKNSDGHHNTSNFMNLFLDNISFWKLFGFENINFVIDKYFTL
                     VGKTNLGYVEFICDNNKNIDIYFGEWKTSSSKSTIFSGNGRNVVVEPIYNPDTGEDIS
                     TSLDFSYEPLYGIDRYINKVLIAPDLYTSLININTNYYSNEYYPEIIVLNPNTFHKKV
                     NINLDSSSFEYKWSTEGSDFILVRYLEESNKKILQKIRIKGILSNTQSFNKMSIDFKD
                     IKKLSLGYIMSNFKSFNSENELDRDHLGFKIIDNKTYYYDEDSKLVKGLININNSLFY
                     FDPIEFNLVTGWQTINGKKYYFDINTGAALTSYKIINGKHFYFNNDGVMQLGVFKGPD
                     GFEYFAPANTQNNNIEGQAIVYQSKFLTLNGKKYYFDNDSKAVTGWRIINNEKYYFNP
                     NNAIAAVGLQVIDNNKYYFNPDTAIISKGWQTVNGSRYYFDTDTAIAFNGYKTIDGKH
                     FYFDSDCVVKIGVFSTSNGFEYFAPANTYNNNIEGQAIVYQSKFLTLNGKKYYFDNNS
                     KAVTGWQTIDSKKYYFNTNTAEAATGWQTIDGKKYYFNTNTAEAATGWQTIDGKKYYF
                     NTNTAIASTGYTIINGKHFYFNTDGIMQIGVFKGPNGFEYFAPANTDANNIEGQAILY
                     QNEFLTLNGKKYYFGSDSKAVTGWRIINNKKYYFNPNNAIAAIHLCTINNDKYYFSYD
                     GILQNGYITIERNNFYFDANNESKMVTGVFKGPNGFEYFAPANTHNNNIEGQAIVYQN
                     KFLTLNGKKYYFDNDSKAVTGWQTIDGKKYYFNLNTAEAATGWQTIDGKKYYFNLNTA
                     EAATGWQTIDGKKYYFNTNTFIASTGYTSINGKHFYFNTDGIMQIGVFKGPNGFEYFA
                     PANTHNNNIEGQAILYQNKFLTLNGKKYYFGSDSKAVTGLRTIDGKKYYFNTNTAVAV
                     TGWQTINGKKYYFNTNTSIASTGYTIISGKHFYFNTDGIMQIGVFKGPDGFEYFAPAN
                     TDANNIEGQAIRYQNRFLYLHDNIYYFGNNSKAATGWVTIDGNRYYFEPNTAMGANGY
                     KTIDNKNFYFRNGLPQIGVFKGSNGFEYFAPANTDANNIEGQAIRYQNRFLHLLGKIY
                     YFGNNSKAVTGWQTINGKVYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIYG"
     gene            complement(24318..25016)
                     /gene="tcdC"
                     /locus_tag="KOU88_003274"
     CDS             complement(24318..25016)
                     /gene="tcdC"
                     /locus_tag="KOU88_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosylating toxin anti-sigma factor TcdC"
                     /protein_id="HBK3213128.1"
                     /translation="MFSKKNEGNEFSNEGKGSSKKIIKFFKSTKGIALLAFILGVFFG
                     NISSPSCSEDHEEVISNQTSVIDSQKTEIETLNSKLSDAEPWFKMKDDEKKAIEAENQ
                     RKAEEAKKAEEAKKAEEQRKKEEEEKKGYDTGITYDQLARTPDDYKYKKVKFEGKVIQ
                     VIEDGDEVQIRLAVSGNYDKVVLCSYKKSITPSRVLEDDYITIRGISAGTITYESTMG
                     GNITIPGIAVEKIN"
     gene            25442..25687
                     /locus_tag="KOU88_003275"
     CDS             25442..25687
                     /locus_tag="KOU88_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pathogenicity locus"
                     /protein_id="HBK3213129.1"
                     /translation="MGELQKIPGVGKATEKSLIMLGYTTIKSLKDANPAQMYEKECLM
                     RGQHIDRCQLYVYRCAVYFASTENPEPEKLKWWYWKD"
     gene            complement(25905..26174)
                     /locus_tag="KOU88_003276"
     CDS             complement(25905..26174)
                     /locus_tag="KOU88_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3795 domain-containing protein"
                     /protein_id="HBK3213130.1"
                     /translation="MFESRCGVCCDSCTKKEQVNCTGCPTMEKPFWGGECKVKTCCES
                     KELNHCGECDTFPCDMLLNKGKDQGFDPMVNIEQCRKWLEETVSN"
BASE COUNT        10527 a         2920 c         4133 g         9268 t
ORIGIN      
        1 atacacttgc actcaattta gttactccta agctttatga actaaaagtt tattttgaag
       61 cctattttta ttaaaagaga ttttattttt ctaaataatc atctatatac agtattgcgt
      121 ttcttttatt tattcataat ttattttctt attaaagttt ttctatattc atattttcca
      181 tattacttta cttttaattt tatacgaatt atcaaaaata aaatagttat tagaaaaaaa
      241 taaaagtaat tgcaaagctt gcaattactt acttctatat taattactat accataaaat
      301 aacaaaaaaa tcaagtcgag taatccttca acttaagtga tatactaggt attaataatt
      361 tttaattaat aaaatataac tagaggaaaa tctacatttt ctcaatttct ttaattaaat
      421 tgacctctaa ttaagtaatt ataaggagaa aaattatgaa tttagcaaag ggattagatg
      481 ttttaaaaat ttcatcaaat gtattcggtg aagataaagt tatgtatatt cctgtaatct
      541 acacagaaga tgatgcaaca cttattgaca caggtcttcc gggtcaaggt gatttaataa
      601 ttgatgctct taataaaagt aacacgagct ttgataggtt aaaaaatata ataattactc
      661 atcatgatat agaccatata ggaaacataa attatctaag agaaaaatct aagaataata
      721 tcaaagtata tgcatacaaa agtgaagtca gctatataac aggagaagaa actcctttta
      781 aactttatat gttggaacaa atggtagata aaattgatga taagatgctt agtatgctaa
      841 atgttatggg acttggattt aaatcatcat atactaaagt agatgtgtca ttagataacc
      901 atgaaaaatt gaatctaggt gaggaaatag aagttataca tacaggaggt cacactagag
      961 gtcacatatg tctttattta aaagagtcta aagtacttat tgctggagat ttgttacagg
     1021 tagaaaatgg agaacttaag cctgttgatg tgatgtacag caacaaacaa gagttaaaag
     1081 atgctattaa aaatataagt aattataata tagaaacgat agtttttagt catggtggat
     1141 tatatcaaag aaacataatt ggaacattga aaaacctaat tattgagtag tactatatga
     1201 tttacaataa tttcttaaat tacttaaaat tatatctaaa gatgtagaat caaaattaaa
     1261 tataagtaat aagaattttg ctttaaaatt atacttaagt gttaagggtg atatgtagta
     1321 ttacaagtat tttagaatat agttttttat agtaatttta aggttctaca atacttcagt
     1381 tgaaaaatat ttaacagcat agtataatgg gaaagaaaat actttaaata aactttagta
     1441 tacaaagtga agaaaaatat ttaaattata tataatattg tagagtgagg taaaatattt
     1501 aagttatata tcataataca gagtgaagaa aaatatttag ataatgtacc ataatacaaa
     1561 gtgagtaaaa atatttaaat catgtatcat aatgcaaagc gaagaaaaat atttaaataa
     1621 tgtaccataa tgcagagtga gtaaaaatat ttaaataatg tgttataata caaagcgaat
     1681 aagattattt aaagcatgta ttataatata aagtgcgtaa aaatatttaa atcatgtatc
     1741 ataatacaaa gtaaaaaaga ttatttaaac catatatcat aatgcaaagt gaagaaaaat
     1801 gtttaaatta tgtatcataa tataagcaga gtgaagaaaa aaatttaaat aatatatcat
     1861 aatgtagagt gagtaaaaat atttaaatca tgtatcataa tataagcaga gtgaagaaaa
     1921 tatttaaatc atgtatcata atataagcag agtgaagaaa aatatttaaa taatatatca
     1981 taatgtggag tgaggaaaaa tatttaagtt atgtatcata atacaaagta aagaaaatca
     2041 tttaaattat atatcataaa aataatatga aatattgaac actcataata ttagagactt
     2101 taatatttta attgataggt tatattattt ataacattaa aaatacaatt tacataaaat
     2161 agacatatga aaaataaaaa attatataat aattatggga atgaggttct cccttggatg
     2221 ataatatcct aaactgccaa tgagctgatg acttctatga tatcatagat gccaccagct
     2281 ttttttgttg tttaaatcaa taaaatggag gtgaagtact tactaaattt ttatttttta
     2341 aatttgaaga aatatttaat taatagaaaa aatagtagat tatatgttaa ttattttatt
     2401 aagaatgggt taagagtgta cctatatcct atcaatttaa aaaacaatta tgatagtcat
     2461 tacattgact acagttgatg caataaaact ttcaaaaaat cttatgatgc aaatagaaag
     2521 gaattaaaat gatagaaaaa tttaaaactt taatatggat taaaatgata ataagaatta
     2581 aaagcgttta taaaacatat ggtggactat tttttttagg actcataggt ataccagttg
     2641 gtgcaattat aggtcttata gacaccatat ttggaacggt tcttctaaaa gttacagata
     2701 ttcgagaaac atatccaatg tatctgatac catttttagc agtagtagga gttgttattg
     2761 cttattgcta ttttaaattt ggaggaaaaa gtagtaaagg aatgaatcta atatttgagg
     2821 tagggcatgg agaagaagaa attattcctt taagattggt tccatttata atatcaggta
     2881 catggttaac ccatttattt ggtggtagtg caggacgaga aggagttgct gttcagattg
     2941 gtgcaacttt ttcacattgg gtaggtaaaa ggttgcctat aaaaaatgct tctagtattt
     3001 ttctagtaac tggtatggca gctggttttg caggattatt tgagacacca atagcagcaa
     3061 tactatttgc tatggaggtt ttggttgctg gttcactgga gtatcaatcg ctttttcctg
     3121 cgtttactgc ttcttttaca gcaagtgcag tatcaaaagc tttagggtta gagaaatttt
     3181 cttttgcact ttcttctgaa gttgtatttg acttgtcaat attttggaag cttattgttt
     3241 taggaattat ttttggaatg gttggtggag catttgcatg gtgtctgaaa ttgtcaaaaa
     3301 gaaaaatagg gaatagatta aaaaatccta tgataaggat tgctattatt ggagtatgtc
     3361 ttagtgtatt attcctttta ttttataaag gaagatattc aggtttaggg acaaatttaa
     3421 ttcaaaatag tttctatggt ggagaaattt attcatttga ctggctgtta aagtttatac
     3481 ttacaatact gactttgtca gcaggttttc aaggaggaga ggttacacct ttgttttcca
     3541 ttggagctag tcttggtgta ttgttagcag gattttttaa tttgccaatt gaattagttg
     3601 cagcgcttgg ctatgctagt gtctttggta gtgctacaaa tacttttttt gcacctgtat
     3661 ttataggggc agaagttttt gggtacagct atttacctta tttctttgta gtatgcgcta
     3721 tttcatatat atttaatatg gataaatcta tttattcact acaaaaaatt tcaacaaaac
     3781 aataaataaa acaacataat gtatgattag aagagaaaga atattagaga aaggataggg
     3841 taggaatatg ttgacaagtt tagctttgat ttttttatta ggaatggcct cgggaggtat
     3901 ttttaagagg ataaagttac ctaacttatt gggaatgtta cttacaggaa ttatattagg
     3961 tccatatgtt ttaaatttga ttgataattc aatactagat atttcttctg accttagaaa
     4021 gattgcattg attattatat taacaagggc tggattatct ttagatataa acgatttgaa
     4081 gaaagtggga agacctgctg tacttatgtg ctttattcca gctacttttg aaattatcgg
     4141 aatgatagtt ttagcaccaa agttactagg cgtttctata ttggaagcag cagtcatggg
     4201 tgcagtagta ggagcagttt ctcccgcaat tattgtacct aaaatgctta aattaatgga
     4261 agaaggttat ggtacagaaa aaagtattcc acagatgctt ttagcaggaa cttctataga
     4321 cgatattttc gtaattgtga tgtttacagt attcacaggg ttggcacaag gaaatagtat
     4381 atcagctatt agttttttac aaattccagt atcaattata ttaggtgtaa tagctggagc
     4441 agtgattgga atctgtttag cagtattttt taagaaggtt catatgagag attctgctaa
     4501 aggggtgttg cttttaagta tctcattttt aatgataagt ttagagactg ctttagaggg
     4561 tattgtgcca ttttctggat tattagcagt tatgagtatt gggattttcc ttcagataaa
     4621 atatcgtgta gttgcaagaa gattgtctat aaagtattcg aaactatggg ttggtgctga
     4681 aattctcttg tttgttttgg taggggcaac agtagatata agttatgcat ttaaagcagg
     4741 aattggagct gtaattttaa tatttggagt tcttttattc cgtatggtag gagtattctt
     4801 ctgccttatt aagacaaatt tgacaataaa ggaaaggttg ttctgtatga ttggctatat
     4861 tccaaaggct acagtacagg cagcaatagg aggtgtacca cttgcaatgg ggatggcatc
     4921 tggacaactt attttgacgt tagcagttct agctatactt ataactgcac ctcttggagc
     4981 ttttggaatt gatgtaactt ataaaaaatt attaacttct gtaaaaggcg agagtaagta
     5041 aaaataaaga ttattttaac tggtaagtta tattttggaa aaggattata ctattgaata
     5101 caatataaaa aaatcatttg ggagattaag aaggtagaag ttaagaacag attttaaggt
     5161 atgttatgat tattagaatt gattttgtga aattattatt gtaatattta attatataga
     5221 taaagaagcg gagtgataac tatgtgttta aaaaaattat caaaattaga gttagttatt
     5281 atgaaattta tttggaattt agatataaaa accaattcat atgagattat tgattatatg
     5341 aaagaagaac ataatttacc agaaaaagta gctttaaaaa ctttatcaaa actatcaaag
     5401 aaaagattct tatatgttca agaaacaggc aagtgtatgt attatacagt tgcaataaaa
     5461 gaaaaggcat atttagagtt tatatcaaga aatgtgcaaa atcttttgaa gaataatttt
     5521 ataaggaatt tattagtatc atttcacgaa gaggagctaa cagaggaaaa gataaagtcg
     5581 ttagaaaact gggtagtaaa ttgggaagaa gcttatgtat aaatgttatt atttttatta
     5641 caatttagat aattttggtt ttgtaagctc tgcaactatt tttagatggt tgcagagttt
     5701 atttttattt tttattccct taagcaatac ttaaaagtaa acgcatttat atttactaac
     5761 ttcaattact tctaatactt aaattacttt ttaaaaatat tttgatatgt catctctata
     5821 gtaatctaga acttgtttct attctttata taaagttttt atgaatgata tatataatat
     5881 tcgttcattt gattaaaaat aacaaaatat taaataattc tactctgata gtttgttaaa
     5941 aaaataataa aaaatattaa taaacaaaaa aaaattatct taagagagga gaatgttcta
     6001 aaatataaaa aggtttctag atttcataaa agatactatt ttagtcttga aaatatttag
     6061 tttgaaaaga ttttaattta atgattgatt aagttaaaaa tgtgtatgta ataaatttta
     6121 ttttatttat tgactaaatt ataaagttta cataattatt taataattat gtaattgtta
     6181 cttgaaaatt gatctatttt aaaatctagt tataacttca aaaaagactg aaaattaaga
     6241 aaaaagaaat ataaatataa aaacatgtca tatagatttt ttttatttta ctttaataaa
     6301 atgatttgtt tttacaatac tttattaata taaagtttat tgctaaaata ctttatttat
     6361 tagaaaaaga ttactaatta attattaaaa ttaatgtatt cataatgcat attttcatat
     6421 aaaatttaat ttatttgccg attatataat tataatgact gatttaattc cgatgttgtc
     6481 aaaattttca aataaatcat cattataaat ataagagagg atgattttat gcaaaagtct
     6541 ttttatgaat taattgtttt agcaagaaat aactcagtag atgatttgca agaaatttta
     6601 tttatgttta agccattagt aaaaaaactt agtagagttt tacattatga agagggagaa
     6661 acagatttaa taatattttt tattgaatta ataaaaaata ttaaattaag tagcttttca
     6721 gaaaaaagcg atgctattat agtcaaatat attcataaat cattactgaa taagactttt
     6781 gagttgtcta gaagatattc taaaatgaag tttaattttg tagaatttga tgaaaatatc
     6841 ttaaatatga aaaataatta tcaaagtaag tctgtttttg aggaagatat ttgttttttc
     6901 gaatatattt tgaaagaatt atctggtatt caaagaaaag ttatttttta taaatattta
     6961 aaaggatatt ctgatagaga aatatcagtg aaattaaaaa tatctagaca agctgttaat
     7021 aaggctaaaa atagagcatt taaaaaaata aaaaaagact atgaaaatta ttttaacttg
     7081 taattaatga gcttaaagaa atatttacaa tagaaatcaa attttagaat taactttatt
     7141 gtaaaatcaa taacttaatc taagaatatc ttaattttta tattttatat agaacaaagt
     7201 ttacatattt atttcagaca acgtctttat tcaatcgaag agcaaattaa tcaactgagt
     7261 gtcttaaatt taaaatgtta ggaagtgaat gtatatgaaa acctaagtag atattagtat
     7321 attttataaa tagaaaggag gatatataaa agagttttag catttagatg taaaaatatt
     7381 atagtaaagg agaaaatttt atgagtttag ttaatagaaa acagttagaa aaaatggcaa
     7441 atgtaagatt tcgtactcaa gaagatgaat atgttgcaat attggatgct ttagaagaat
     7501 atcataatat gtcagagaat actgtagtcg aaaaatattt aaaattaaaa gatataaata
     7561 gtttaacaga tatttatata gatacatata aaaaatctgg tagaaataaa gccttaaaaa
     7621 aatttaagga atatctagtt acagaagtat tagagctaaa gaataataat ttaactccag
     7681 ttgagaaaaa tttacatttt gtttggattg gaggtcaaat aaatgacact gctattaatt
     7741 atataaatca atggaaagat gtaaatagtg attataatgt taatgttttt tatgatagta
     7801 atgcattttt gataaacaca ttgaaaaaaa ctgtagtaga atcagcaata aatgatacac
     7861 ttgaatcatt tagagaaaac ttaaatgacc ctagatttga ctataataaa ttcttcagaa
     7921 aacgtatgga aataatttat gataaacaga aaaatttcat aaactactat aaagctcaaa
     7981 gagaagaaaa tcctgaactt ataattgatg atattgtaaa gacatatctt tcaaatgagt
     8041 attcaaagga gatagatgaa cttaatacct atattgaaga atccttaaat aaaattacac
     8101 agaatagtgg aaatgatgtt agaaactttg aagaatttaa aaatggagag tcattcaact
     8161 tatatgaaca agagttggta gaaaggtgga atttagctgc tgcttctgac atattaagaa
     8221 tatctgcatt aaaagaaatt ggtggtatgt atttagatgt tgatatgtta ccaggaatac
     8281 aaccagactt atttgagtct atagagaaac ctagttcagt aacagtggat ttttgggaaa
     8341 tgacaaagtt agaagctata atgaaataca aagaatatat accagaatat acctcagaac
     8401 attttgacat gttagacgaa gaagttcaaa gtagttttga atctgttcta gcttctaagt
     8461 cagataaatc agaaatattc tcatcacttg gtgatatgga ggcatcacca ctagaagtta
     8521 aaattgcatt taatagtaag ggtattataa atcaagggct aatttctgtg aaagactcat
     8581 attgtagcaa tttaatagta aaacaaatcg agaatagata taaaatattg aataatagtt
     8641 taaatccagc tattagcgag gataatgatt ttaatactac aacgaatacc tttattgata
     8701 gtataatggc tgaagctaat gcagataatg gtagatttat gatggaacta ggaaagtatt
     8761 taagagttgg tttcttccca gatgttaaaa ctactattaa cttaagtggc cctgaagcat
     8821 atgcggcagc ttatcaagat ttattaatgt ttaaagaagg cagtatgaat atccatttga
     8881 tagaagctga tttaagaaac tttgaaatct ctaaaactaa tatttctcaa tcaactgaac
     8941 aagaaatggc tagcttatgg tcatttgacg atgcaagagc taaagctcaa tttgaagaat
     9001 ataaaaggaa ttattttgaa ggttctcttg gtgaagatga taatcttgat ttttctcaaa
     9061 atatagtagt tgacaaggag tatcttttag aaaaaatatc ttcattagca agaagttcag
     9121 agagaggata tatacactat attgttcagt tacaaggaga taaaattagt tatgaagcag
     9181 catgtaactt atttgcaaag actccttatg atagtgtact atttcagaaa aatatagaag
     9241 attcagaaat tgcatattat tataatcctg gagatggtga aatacaagaa atagacaagt
     9301 ataaaattcc aagtataatt tctgatagac ctaagattaa attaacattt attggtcatg
     9361 gtaaagatga atttaatact gatatatttg caggttttga tgtagattca ttatccacag
     9421 aaatagaagc agcaatagat ttagctaaag aggatatttc tcctaagtca atagaaataa
     9481 atttattagg atgtaatatg tttagctact ctatcaacgt agaggagact tatcctggaa
     9541 aattattact taaagttaaa gataaaatat cagaattaat gccatctata agtcaagact
     9601 ctattatagt aagtgcaaat caatatgaag ttagaataaa tagtgaagga agaagagaat
     9661 tattggatca ttctggtgaa tggataaata aagaagaaag tattataaag gatatttcat
     9721 caaaagaata tatatcattt aatcctaaag aaaataaaat tacagtaaaa tctaaaaatt
     9781 tacctgagct atctacatta ttacaagaaa ttagaaataa ttctaattca agtgatattg
     9841 aactagaaga aaaagtaatg ttaacagaat gtgagataaa tgttatttca aatatagata
     9901 cgcaaattgt tgaggaaagg attgaagaag ctaagaattt aacttctgac tctattaatt
     9961 atataaaaga tgaatttaaa ctaatagaat ctatttctga tgcactatgt gacttaaaac
    10021 aacagaatga attagaagat tctcatttta tatcttttga ggacatatca gagactgatg
    10081 agggatttag tataagattt attaataaag aaactggaga atctatattt gtagaaactg
    10141 aaaaaacaat attctctgaa tatgctaatc atataactga agagatttct aagataaaag
    10201 gtactatatt tgatactgta aatggtaagt tagtaaaaaa agtaaattta gatactacac
    10261 acgaagtaaa tactttaaat gctgcatttt ttatacaatc attaatagaa tataatagtt
    10321 ctaaagaatc tcttagtaat ttaagtgtag caatgaaagt ccaagtttac gctcaattat
    10381 ttagtactgg tttaaatact attacagatg cagccaaagt tgttgaatta gtatcaactg
    10441 cattagatga aactatagac ttacttccta cattatctga aggattacct ataattgcaa
    10501 ctattataga tggtgtaagt ttaggtgcag caatcaaaga gctaagtgaa acgagtgacc
    10561 cattattaag acaagaaata gaagctaaga taggtataat ggcagtaaat ttaacaacag
    10621 ctacaactgc aatcattact tcatctttgg gggtagctag tggatttagt atacttttag
    10681 ttcctttagc aggaatttca gcaggtatac caagcttagt aaacaatgaa cttgtacttc
    10741 gagataaggc aacaaaggtt gtagattatt ttaaacatgt ttcattagtt gaaactgaag
    10801 gagtatttac tttattagat gataaaataa tgatgccaca agatgattta gtgatatcag
    10861 aaatagattt taataataat tcaatagttt taggtaaatg tgaaatctgg agaatggaag
    10921 gtggttcagg tcatactgta actgatgata tagatcactt cttttcagca ccatcaataa
    10981 catatagaga gccacactta tctatatatg acgtattgga agtacaaaaa gaagaacttg
    11041 atttgtcaaa agatttaatg gtattaccta atgctccaaa tagagtattt gcttgggaaa
    11101 caggatggac accaggttta agaagcttag aaaatgatgg cacaaaactg ttagaccgta
    11161 taagagataa ctatgaaggt gagttttatt ggagatattt tgcttttata gctgatgctt
    11221 taataacaac attaaaacca agatatgaag atactaatat aagaataaat ttagatagta
    11281 atactagaag ttttatagtt ccaataataa ctacagaata tataagagaa aaattatcat
    11341 attctttcta tggttcagga ggaacttatg cattgtctct ttctcaatat aatatgggta
    11401 taaatataga attaagtgaa agtgatgttt ggattataga tgttgataat gttgtgagag
    11461 atgtaactat agaatctgat aaaattaaaa aaggtgattt aatagaaggt attttatcta
    11521 cactaagtat tgaagagaat aaaattatct taaatagcca tgagattaat ttttctggtg
    11581 aggtaaatgg aagtaatgga tttgtttctt taacattttc aattttagaa ggaataaatg
    11641 caattataga agttgattta ttatctaaat catataaatt acttatttct ggcgaattaa
    11701 aaatattgat gttaaattca aatcatattc aacagaaaat agattatata ggattcaata
    11761 gcgaattaca gaaaaatata ccatatagct ttgtagatag tgaaggaaaa gagaatggtt
    11821 ttattaatgg ttcaacaaaa gaaggtttat ttgtatctga attacctgat gtagttctta
    11881 taagtaaggt ttatatggat gatagtaagc cttcatttgg atattatagt aataatttga
    11941 aagatgtcaa agttataact aaagataatg ttaatatatt aacaggttat tatcttaagg
    12001 atgatataaa aatctctctt tctttgactc tacaagatga aaaaactata aagttaaata
    12061 gtgtgcattt agatgaaagt ggagtagctg agattttgaa gttcatgaat agaaaaggta
    12121 atacaaatac ttcagattct ttaatgagct ttttagaaag tatgaatata aaaagtattt
    12181 tcgttaattt cttacaatct aatattaagt ttatattaga tgctaatttt ataataagtg
    12241 gtactacttc tattggccaa tttgagttta tttgtgatga aaatgataat atacaaccat
    12301 atttcattaa gtttaataca ctagaaacta attatacttt atatgtagga aatagacaaa
    12361 atatgatagt ggaaccaaat tatgatttag atgattctgg agatatatct tcaactgtta
    12421 tcaatttctc tcaaaagtat ctttatggaa tagacagttg tgttaataaa gttgtaattt
    12481 caccaaatat ttatacagat gaaataaata taacgcctgt atatgaaaca aataatactt
    12541 atccagaagt tattgtatta gatgcaaatt atataaatga aaaaataaat gttaatatca
    12601 atgatctatc tatacgatat gtatggagta atgatggtaa tgattttatt cttatgtcaa
    12661 ctagtgaaga aaataaggtg tcacaagtta aaataagatt cgttaatgtt tttaaagata
    12721 agactttggc aaataagcta tcttttaact ttagtgataa acaagatgta cctgtaagtg
    12781 aaataatctt atcatttaca ccttcatatt atgaggatgg attgattggc tatgatttgg
    12841 gtctagtttc tttatataat gagaaatttt atattaataa ctttggaatg atggtatctg
    12901 gattaatata tattaatgat tcattatatt attttaaacc accagtaaat aatttgataa
    12961 ctggatttgt gactgtaggc gatgataaat actactttaa tccaattaat ggtggagctg
    13021 cttcaattgg agagacaata attgatgaca aaaattatta tttcaaccaa agtggagtgt
    13081 tacaaacagg tgtatttagt acagaagatg gatttaaata ttttgcccca gctaatacac
    13141 ttgatgaaaa cctagaagga gaagcaattg attttactgg aaaattaatt attgacgaaa
    13201 atatttatta ttttgatgat aattatagag gagctgtaga atggaaagaa ttagatggtg
    13261 aaatgcacta ttttagccca gaaacaggta aagcttttaa aggtctaaat caaataggtg
    13321 attataaata ctatttcaat tctgatggag ttatgcaaaa aggatttgtt agtataaatg
    13381 ataataaaca ctattttgat gattctggtg ttatgaaagt aggttacact gaaatagatg
    13441 gcaagcattt ctactttgct gaaaacggag aaatgcaaat aggagtattt aatacagaag
    13501 atggatttaa atattttgct catcataatg aagatttagg aaatgaagaa ggtgaagaaa
    13561 tctcatattc tggtatatta aatttcaata ataaaattta ctattttgat gattcattta
    13621 cagctgtagt tggatggaaa gatttagagg atggttcaaa gtattatttt gatgaagata
    13681 cagcagaagc atatataggt ttgtcattaa taaatgatgg tcaatattat tttaatgatg
    13741 atggaattat gcaagttgga tttgtcacta taaatgataa agtcttctac ttctctgact
    13801 ctggaattat agaatctgga gtacaaaaca tagatgacaa ttatttctat atagatgata
    13861 atggtatagt tcaaattggt gtatttgata cttcagatgg atataaatat tttgcacctg
    13921 ctaatactgt aaatgataat atttacggac aagcagttga atatagtggt ttagttagag
    13981 ttggggaaga tgtatattat tttggagaaa catatacaat tgagactgga tggatatatg
    14041 atatggaaaa tgaaagtgat aaatattatt tcaatccaga aactaaaaaa gcatgcaaag
    14101 gtattaattt aattgatgat ataaaatatt attttgatga gaagggcata atgagaacgg
    14161 gtcttatatc atttgaaaat aataattatt actttaatga gaatggtgaa atgcaatttg
    14221 gttatataaa tatagaagat aagatgttct attttggtga agatggtgtc atgcagattg
    14281 gagtatttaa tacaccagat ggatttaaat actttgcaca tcaaaatact ttggatgaga
    14341 attttgaggg agaatcaata aactatactg gttggttaga tttagatgaa aagagatatt
    14401 attttacaga tgaatatatt gcagcaactg gttcagttat tattgatggt gaggagtatt
    14461 attttgatcc tgatacagct caattagtga ttagtgaata gataaaaata tgttaaatat
    14521 atcctcttat acttaaatat ataaaaataa acaaaatgat acactacata aagtgttcta
    14581 tctaatatga agatttacca ataaaaaggt ggactatgat gaatgcacag tagttcacct
    14641 ttttatattt ctaatggtaa caaaatattt ttttatataa acctaggagg cgttatgaat
    14701 atgacaatat cttttttatc agagcatata tttataaagt tagtaatttt aactatatca
    14761 tttgatacat tattaggatg tttaagtgca ataaaaagtc gtaaatttaa ttctagtttt
    14821 ggaatagatg gaggaatcag aaaagtagca atgatagcat gtatattttt tttatcagta
    14881 gttgacattc ttacaaagtt taacttttta tttatgttac cacaagattg tatcaatttt
    14941 ttaagactaa aacatcttgg aatatctgaa tttttctcta ttttatttat tttatatgaa
    15001 agtgtaagta tattaaaaaa tatgtgctta tgtggattac cagtacctaa gagattaaag
    15061 gaaaaaatag caattttact agatgcaatg acagatgaaa tgaatgctaa ggatgaaaag
    15121 taagtaatgg tagatataat aaagatatta acaaataaaa agtgttatcc aaataagaat
    15181 agctgaaagt tatcataatt catgaaacta ataatgaaaa cgagggagca gatgccaaga
    15241 gacacacaag tattaaatac atataatttc gaagcaagtg ttcattacta tatagatgac
    15301 aaggtagtat atcaaacatt ggttcacaaa gatggtgcat ggtcagttgg taaaatctat
    15361 taagctacat tagttacaga tatcacaaac tataatagtt aaacatagaa atatgtgtaa
    15421 attgtgatgg aaattattca aaaacacaaa aatacgtgat gaaggacaaa atgatataga
    15481 aaataagtat caaaccttaa taaatgattt aattgatagt ttaaaagtta taggaaaaat
    15541 atataaagaa ataaaaacat taaaaaaata taagatatgt ttacaaatta ctatcagaca
    15601 atctccttat ctaatagaag agtcaattaa ctaattgagt atctttaaat tgaaatgtta
    15661 ggaagtgatt taaatatgaa aacttaaatt ataaaaaatc aatattaatt tatttttaaa
    15721 aaatagaaag gagtgtataa gatttatttt caaagtttaa aaacaagaaa atcaatttaa
    15781 atttcagaag gaataaatgt ggttatagaa gtggatttat tatcaaaaat aataatacta
    15841 ggaggttttt atgtctttaa tatctaaaga agagttaata aaactcgcat atagcattag
    15901 accaagagaa aatgagtata aaactatact aactaattta gacgaatata ataagttaac
    15961 tacaaacaat aatgaaaata aatatttaca attaaaaaaa ctaaatgaat caattgatgt
    16021 ttttatgaat aaatataaaa cttcaagcag aaatagagca ctctctaatc taaaaaaaga
    16081 tatattaaaa gaagtaattc ttattaaaaa ttccaataca agccctgtag aaaaaaattt
    16141 acattttgta tggataggtg gagaagtcag tgatattgct cttgaataca taaaacaatg
    16201 ggctgatatt aatgcagaat ataatattaa actgtggtat gatagtgaag cattcttagt
    16261 aaatacacta aaaaaggcta tagttgaatc ttctaccact gaagcattac agctactaga
    16321 ggaagagatt caaaatcctc aatttgataa tatgaaattt tacaaaaaaa ggatggaatt
    16381 tatatatgat agacaaaaaa ggtttataaa ttattataaa tctcaaatca ataaacctac
    16441 agtacctaca atagatgata ttataaagtc tcatctagta tctgaatata atagagatga
    16501 aactgtatta gaatcatata gaacaaattc tttgagaaaa ataaatagta atcatgggat
    16561 agatatcagg gctaatagtt tgtttacaga acaagagtta ttaaatattt atagtcagga
    16621 gttgttaaat cgtggaaatt tagctgcagc atctgacata gtaagattat tagccctaaa
    16681 aaattttggc ggagtatatt tagatgttga tatgcttcca ggtattcact ctgatttatt
    16741 taaaacaata tctagaccta gctctattgg actagaccgt tgggaaatga taaaattaga
    16801 ggctattatg aagtataaaa aatatataaa taattataca tcagaaaact ttgataaact
    16861 tgatcaacaa ttaaaagata attttaaact cattatagaa agtaaaagtg aaaaatctga
    16921 gatattttct aaattagaaa atttaaatgt atctgatctt gaaattaaaa tagctttcgc
    16981 tttaggcagt gttataaatc aagccttgat atcaaaacaa ggttcatatc ttactaacct
    17041 agtaatagaa caagtaaaaa atagatatca atttttaaac caacacctta acccagccat
    17101 agagtctgat aataacttca cagatactac taaaattttt catgattcat tatttaattc
    17161 agctaccgca gaaaactcta tgtttttaac aaaaatagca ccatacttac aagtaggttt
    17221 tatgccagaa gctcgctcca caataagttt aagtggtcca ggagcttatg cgtcagctta
    17281 ctatgatttc ataaatttac aagaaaatac tatagaaaaa actttaaaag catcagattt
    17341 aatagaattt aaattcccag aaaataatct atctcaattg acagaacaag aaataaatag
    17401 tctatggagc tttgatcaag caagtgcaaa atatcaattt gagaaatatg taagagatta
    17461 tactggtgga tctctttctg aagacaatgg ggtagacttt aataaaaata ctgccctcga
    17521 caaaaactat ttattaaata ataaaattcc atcaaacaat gtagaagaag ctggaagtaa
    17581 aaattatgtt cattatatca tacagttaca aggagatgat ataagttatg aagcaacatg
    17641 caatttattt tctaaaaatc ctaaaaatag tattattata caacgaaata tgaatgaaag
    17701 tgcaaaaagc tactttttaa gtgatgatgg agaatctatt ttagaattaa ataaatatag
    17761 gatacctgaa agattaaaaa ataaggaaaa agtaaaagta acctttattg gacatggtaa
    17821 agatgaattc aacacaagcg aatttgctag attaagtgta gattcacttt ccaatgagat
    17881 aagttcattt ttagatacca taaaattaga tatatcacct aaaaatgtag aagtaaactt
    17941 acttggatgt aatatgttta gttatgattt taatgttgaa gaaacttatc ctgggaagtt
    18001 gctattaagt attatggaca aaattacttc cactttacct gatgtaaata aaaattctat
    18061 tactatagga gcaaatcaat atgaagtaag aattaatagt gagggaagaa aagaacttct
    18121 ggctcactca ggtaaatgga taaataaaga agaagctatt atgagcgatt tatctagtaa
    18181 agaatacatt ttttttgatt ctatagataa taagctaaaa gcaaagtcca agaatattcc
    18241 aggattagca tcaatatcag aagatataaa aacattatta cttgatgcaa gtgttagtcc
    18301 tgatacaaaa tttattttaa ataatcttaa gcttaatatt gaatcttcta ttggtgatta
    18361 catttattat gaaaaattag agcctgttaa aaatataatt cacaattcta tagatgattt
    18421 aatagatgag ttcaatctac ttgaaaatgt atctgatgaa ttatatgaat taaaaaaatt
    18481 aaataatcta gatgagaagt atttaatatc ttttgaagat atctcaaaaa ataattcaac
    18541 ttactctgta agatttatta acaaaagtaa tggtgagtca gtttatgtag aaacagaaaa
    18601 agaaattttt tcaaaatata gcgaacatat tacaaaagaa ataagtacta taaagaatag
    18661 tataattaca gatgttaatg gtaatttatt ggataatata cagttagatc atacttctca
    18721 agttaataca ttaaacgcag cattctttat tcaatcatta atagattata gtagcaataa
    18781 agatgtactg aatgatttaa gtacctcagt taaggttcaa ctttatgctc aactatttag
    18841 tacaggttta aatactatat atgactctat ccaattagta aatttaatat caaatgcagt
    18901 aaatgatact ataaatgtac tacctacaat aacagagggg atacctattg tatctactat
    18961 attagacgga ataaacttag gtgcagcaat taaggaatta ctagacgaac atgacccatt
    19021 actaaaaaaa gaattagaag ctaaggtggg tgttttagca ataaatatgt cattatctat
    19081 agctgcaact gtagcttcaa ttgttggaat aggtgctgaa gttactattt tcttattacc
    19141 tatagctggt atatctgcag gaataccttc attagttaat aatgaattaa tattgcatga
    19201 taaggcaact tcagtggtaa actattttaa tcatttgtct gaatctaaaa aatatggccc
    19261 tcttaagaca gaagatgata aaattttagt tcctattgat gatttagtaa tatcagaaat
    19321 agattttaat aataattcga taaaactagg aacatgtaat atattagcaa tggagggggg
    19381 atcaggacac acagtgactg gtaatataga tcactttttc tcatctccat ctataagttc
    19441 tcatattcct tcattatcaa tttattctgc aataggtata gaaacagaaa atctagattt
    19501 ttcaaaaaaa ataatgatgt tacctaatgc tccttcaaga gtgttttggt gggaaactgg
    19561 agcagttcca ggtttaagat cattggaaaa tgacggaact agattacttg attcaataag
    19621 agatttatac ccaggtaaat tttactggag attctatgct tttttcgatt atgcaataac
    19681 tacattaaaa ccagtttatg aagacactaa tattaaaatt aaactagata aagatactag
    19741 aaacttcata atgccaacta taactactaa cgaaattaga aacaaattat cttattcatt
    19801 tgatggagca ggaggaactt actctttatt attatcttca tatccaatat caacgaatat
    19861 aaatttatct aaagatgatt tatggatatt taatattgat aatgaagtaa gagaaatatc
    19921 tatagaaaat ggtactatta aaaaaggaaa gttaataaaa gatgttttaa gtaaaattga
    19981 tataaataaa aataaactta ttataggcaa tcaaacaata gatttttcag gcgatataga
    20041 taataaagat agatatatat tcttgacttg tgagttagat gataaaatta gtttaataat
    20101 agaaataaat cttgttgcaa aatcttatag tttgttattg tctggggata aaaattattt
    20161 gatatccaat ttatctaata ctattgagaa aatcaatact ttaggcctag atagtaaaaa
    20221 tatagcgtac aattacactg atgaatctaa taataaatat tttggagcta tatctaaaac
    20281 aagtcaaaaa agcataatac attataaaaa agacagtaaa aatatattag aattttataa
    20341 tgacagtaca ttagaattta acagtaaaga ttttattgct gaagatataa atgtatttat
    20401 gaaagatgat attaatacta taacaggaaa atactatgtt gataataata ctgataaaag
    20461 tatagatttc tctatttctt tagttagtaa aaatcaagta aaagtaaatg gattatattt
    20521 aaatgaatcc gtatactcat cttaccttga ttttgtgaaa aattcagatg gacaccataa
    20581 tacttctaat tttatgaatt tatttttgga caatataagt ttctggaaat tgtttgggtt
    20641 tgaaaatata aattttgtaa tcgataaata ctttaccctt gttggtaaaa ctaatcttgg
    20701 atatgtagaa tttatttgtg acaataataa aaatatagat atatattttg gtgaatggaa
    20761 aacatcgtca tctaaaagca ctatatttag cggaaatggt agaaatgttg tagtagagcc
    20821 tatatataat cctgatacgg gtgaagatat atctacttca ctagattttt cctatgaacc
    20881 tctctatgga atagatagat atatcaataa agtattgata gcacctgatt tatatacaag
    20941 tttaataaat attaatacca attattattc aaatgagtac taccctgaga ttatagttct
    21001 taacccaaat acattccaca aaaaagtaaa tataaattta gatagttctt cttttgagta
    21061 taaatggtct acagaaggaa gtgactttat tttagttaga tacttagaag aaagtaataa
    21121 aaaaatatta caaaaaataa gaatcaaagg tatcttatct aatactcaat catttaataa
    21181 aatgagtata gattttaaag atattaaaaa actatcatta ggatatataa tgagtaattt
    21241 taaatcattt aattctgaaa atgaattaga tagagatcat ttaggattta aaataataga
    21301 taataaaact tattactatg atgaagatag taaattagtt aaaggattaa tcaatataaa
    21361 taattcatta ttctattttg atcctataga atttaactta gtaactggat ggcaaactat
    21421 caatggtaaa aaatattatt ttgatataaa tactggagca gctttaacta gttataaaat
    21481 tattaatggt aaacactttt attttaataa tgatggtgtg atgcagttgg gagtatttaa
    21541 aggacctgat ggatttgaat attttgcacc tgccaatact caaaataata acatagaagg
    21601 tcaggctata gtttatcaaa gtaaattctt aactttgaat ggcaaaaaat attattttga
    21661 taatgactca aaagcagtca ctggatggag aattattaac aatgagaaat attactttaa
    21721 tcctaataat gctattgctg cagtcggatt gcaagtaatt gacaataata agtattattt
    21781 caatcctgac actgctatca tctcaaaagg ttggcagact gttaatggta gtagatacta
    21841 ctttgatact gataccgcta ttgcctttaa tggttataaa actattgatg gtaaacactt
    21901 ttattttgat agtgattgtg tagtgaaaat aggtgtgttt agtacctcta atggatttga
    21961 atattttgca cctgctaata cttataataa taacatagaa ggtcaggcta tagtttatca
    22021 aagtaaattc ttaactttga atggtaaaaa atattacttt gataataact caaaagcagt
    22081 taccggatgg caaactattg atagtaaaaa atattacttt aatactaaca ctgctgaagc
    22141 agctactgga tggcaaacta ttgatggtaa aaaatattac tttaatacta acactgctga
    22201 agcagctact ggatggcaaa ctattgatgg taaaaaatat tactttaata ctaacactgc
    22261 tatagcttca actggttata caattattaa tggtaaacat ttttatttta atactgatgg
    22321 tattatgcag ataggagtgt ttaaaggacc taatggattt gaatattttg cacctgctaa
    22381 tacggatgct aacaacatag aaggtcaagc tatactttac caaaatgaat tcttaacttt
    22441 gaatggtaaa aaatattact ttggtagtga ctcaaaagca gttactggat ggagaattat
    22501 taacaataag aaatattact ttaatcctaa taatgctatt gctgcaattc atctatgcac
    22561 tataaataat gacaagtatt actttagtta tgatggaatt cttcaaaatg gatatattac
    22621 tattgaaaga aataatttct attttgatgc taataatgaa tctaaaatgg taacaggagt
    22681 atttaaagga cctaatggat ttgagtattt tgcacctgct aatactcaca ataataacat
    22741 agaaggtcag gctatagttt accagaacaa attcttaact ttgaatggca aaaaatatta
    22801 ttttgataat gactcaaaag cagttactgg atggcaaacc attgatggta aaaaatatta
    22861 ctttaatctt aacactgctg aagcagctac tggatggcaa actattgatg gtaaaaaata
    22921 ttactttaat cttaacactg ctgaagcagc tactggatgg caaactattg atggtaaaaa
    22981 atattacttt aatactaaca ctttcatagc ctcaactggt tatacaagta ttaatggtaa
    23041 acatttttat tttaatactg atggtattat gcagatagga gtgtttaaag gacctaatgg
    23101 atttgaatac tttgcacctg ctaatactca taataataac atagaaggtc aagctatact
    23161 ttaccaaaat aaattcttaa ctttgaatgg taaaaaatat tactttggta gtgactcaaa
    23221 agcagttacc ggattgcgaa ctattgatgg taaaaaatat tactttaata ctaacactgc
    23281 tgttgcagtt actggatggc aaactattaa tggtaaaaaa tactacttta atactaacac
    23341 ttctatagct tcaactggtt atacaattat tagtggtaaa catttttatt ttaatactga
    23401 tggtattatg cagataggag tgtttaaagg acctgatgga tttgaatact ttgcacctgc
    23461 taatacagat gctaacaata tagaaggtca agctatacgt tatcaaaata gattcctata
    23521 tttacatgac aatatatatt attttggtaa taattcaaaa gcggctactg gttgggtaac
    23581 tattgatggt aatagatatt acttcgagcc taatacagct atgggtgcga atggttataa
    23641 aactattgat aataaaaatt tttactttag aaatggttta cctcagatag gagtgtttaa
    23701 agggtctaat ggatttgaat actttgcacc tgctaatacg gatgctaaca atatagaagg
    23761 tcaagctata cgttatcaaa atagattcct acatttactt ggaaaaatat attactttgg
    23821 taataattca aaagcagtta ctggatggca aactattaat ggtaaagtat attactttat
    23881 gcctgatact gctatggctg cagctggtgg acttttcgag attgatggtg ttatatattt
    23941 ctttggtgtt gatggagtaa aagcccctgg gatatatggc taaaatatat gtttgataaa
    24001 aaattattcc tgtgctacta agaaattatt tttatataat aaatattgag atttaattaa
    24061 aagtcatgtg ttattgtaat acatgacttt tagttaaaat ttttctatca tttaataatc
    24121 tattattctt gactatttta taataaaatt catatatgga aatattaata ctaaataatt
    24181 aatagttgat aaaaaataga taatatgcta aaagcaaaaa ctaatttaga gccttgtaac
    24241 tgtttatttg caattataaa aacatcttta aacatattga ctataatata aaatattaac
    24301 tataatacaa aacaatatta attaattttc tctacagcta tccctggtat agttatattt
    24361 ccacccatag ttgattcata agttatagtt ccagcactta tacctcttat agttatgtaa
    24421 tcatcctcta atactcttga aggagttatt gattttttat aactacatag tacaacctta
    24481 tcataatttc cagacacagc taatcttatt tgcacctcat caccatcttc aataacttga
    24541 ataaccttac cttcaaattt tacctttttg tacttataat catcaggtgt tctagctaat
    24601 tggtcataag taataccagt atcatatcct ttcttctcct cttcttcttt tttgcgttgt
    24661 tcttcagcct ttttagcttc ttcagctttt ttagcttctt cagctttacg ttgattttca
    24721 gcttcaatag ctttcttttc gtcgtctttc attttgaacc atggttcagc atcagacaat
    24781 ttgctattta aagtttctat ttctgttttt tgagaatcta taactgatgt ttggttagaa
    24841 atgacctcct catggtcttc agaacaagat ggtgaggata tattgccaaa aaacacgcct
    24901 aaaataaatg ccagtagagc aatacccttt gtgctcttaa agaatttaat tattttctta
    24961 gagcttcctt ttccttcatt actaaattcg ttaccctcat tttttttaga aaacataata
    25021 caatctccct tttattagat atattttatt ttaaaagtta aaaacttaaa ataactagtt
    25081 gactaaaaat tatatattca tattttccta aaatatattt cccctaagca taattttaca
    25141 aaataaagta agaagattca atatattttg aaaaaataag ataaaaatgt cagattataa
    25201 tataattttc ttgaaggtga attttatata ttaaattaaa cataaagtat tttatttgta
    25261 taaaactata ttatgatgta attaagtgac tcagtgattt agaggtggta aaatatatat
    25321 atatgaaaga gcataaataa attgatataa taaaaaatta aatattaaat attaactata
    25381 ataaaaaaat atctggtaat aggtataata taaaaagaat ataccagaaa gaaggtgaag
    25441 tatgggagaa ctacaaaaaa ttccaggggt agggaaagca acagaaaaat ctttaatcat
    25501 gttaggatat acaactatta aatcacttaa agatgcaaac ccagcacaaa tgtatgaaaa
    25561 ggaatgttta atgcgtggac agcacataga cagatgtcag ttatatgtat acagatgtgc
    25621 agtatatttt gcatcaactg aaaatccaga accagaaaaa ttaaagtggt ggtattggaa
    25681 agattaaaaa atcaaaaaag ttagacataa aaaagagttg aatatccgtt ttaaataata
    25741 aaaactaata ctcaactctt ttttagtcgt aaattttatg taaatctatt tgtatggcta
    25801 aatataccca tcaataaatg tataaatata ctaatcaaca aatgactaaa catactacct
    25861 aacaaaggat taaataaatt ccttaacaaa gcattctaaa acaattaatt agaaactgtt
    25921 tcttcaagcc attttctaca ttgctcaata tttaccatag ggtcaaaacc ttggtctttt
    25981 cccttattta aaagcatatc acaagggaaa gtatcacatt caccacaatg attaagttcc
    26041 ttactttcac agcaagtttt aaccttacat tctccacccc aaaatggttt ttccatagtt
    26101 gggcaaccag tgcaatttac ttgttctttt tttgtacaac tgtcacaaca gacaccacat
    26161 cttgattcaa acatattcaa acatcctttc cattatttaa aaatattata aaatgatttt
    26221 agatgaatac aaaagtgcaa atagttgatt ttaggtcatc taaatgttaa acataaaatt
    26281 attagtactg gtaaatttat aaaaactatt ccaaaaatct ttttgaatat ttcaaaacac
    26341 aataaattac ttcaaatccc cttgaatata ttttacagca ttatagattg ctttaaatct
    26401 ctttgaatat tctacaagac tatagattag tttaaatccc tttgaatata ttttacaaca
    26461 ttatagattg ttttaaatct ctttgaatat tctacaagac tatagattag tttaaatccc
    26521 tttgaatatt tcaaaacacc atagattact ttaaatccct ttgaatgttc tataacacta
    26581 taaattactt ttaactttta tataaccata aagtttttat ctggcacttt aaatggagtt
    26641 ttatatcaaa tttgccttcc atcgaataac caaacttaat ttaattacac attccaagat
    26701 tcaaatattc attcaatata tttgataatt ctatgttata gctataatta aatatagatt
    26761 attaaagtta aatatttatt taatatattg aatgattttt tacctatatt taattaagtt
    26821 tcattatata atataaaaat tgtttttg
//
LOCUS       DAFAZV010000057        25128 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFAZV010000057 DAFAZV010000000
VERSION     DAFAZV010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 25128)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25128)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25128
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.057"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..1016
                     /locus_tag="KOU88_003277"
     CDS             <1..1016
                     /locus_tag="KOU88_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sensor domain-containing diguanylate cyclase"
                     /protein_id="HBK3213131.1"
                     /translation="LYINFIVFYLFKFIIDKTKLSMKYELLEKEIIHKEELRLSNECY
                     KIIVEQTDSVVFEWNIKENKSFVSQAWTEKFGYNNACKNIFKEIKDKDLVHSEDKAIF
                     EGFLESIKKKNMHNQAVYRLKKSNGEYIWCRTSITSIYNDENELLRVVGVIVDVDSDI
                     KKYEELRTRAESDSLTNIYNKGTFEKLVEETIVMNTGDKKDALFIIDLDDFKEINDNF
                     GHPFGDFVLKTFADKIQTSFGSKDLVGRIGGDEFVVYMQDYVTEVNLHKKAKELNRVL
                     SDNYTDLSFSFDASVSIGIARYPQDGTSFFELFKNADRALYSIKASGKNSYCLFEEEL
                     YVQ"
     gene            complement(1378..2208)
                     /locus_tag="KOU88_003278"
     CDS             complement(1378..2208)
                     /locus_tag="KOU88_003278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3213132.1"
                     /translation="MSQVSKNYFTTGEFAKICGINKKTLFHYDDIGLFSPELKKENGY
                     RYYSYHQLSIFGIISSLREVKMPLKEIKAYIDKRTPNLLIELLEKKTIDIKNEIEKLN
                     NIQALMESTISFTKNACNIDANTITLKEHEEEYLVKTPVTYKEQFLGDEEENFLYECI
                     NFMDNYELSDYGTIGSIIKGEDIINKDFESYSYLFTKVNKEYKKYPVSIKPKGLYVTA
                     YHKGSYETIYKTYEKLLNFFNQNNLRIGDFVYEEYLLYDISVRDSNEYLTQISAEVKM
                     "
     gene            2281..4008
                     /locus_tag="KOU88_003279"
     CDS             2281..4008
                     /locus_tag="KOU88_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213133.1"
                     /translation="MKKLIHFLKPYRVLIVVVLIFTFLQTLGTLYIPTLTANIVNNGV
                     VKGDIDYIVKTGLMMMIVAGITALSAVLVCKVSANLSSGFCRDIREAVFIKSQDLSIN
                     DFNNIGTASMITRSTSDITLIGQSVFMFIQLVLPAPIITVSGLFLAYSIDKAMTIIIV
                     VVMFLFMLSAFLVGKKLIKLFKMMQIKMDNMNRVLREVVTGVRVIRAFNRSRFEKKRF
                     DRTAIDYSETAISINKIFAVLMPIVMLIMNLGIVSIIWFGGMRVSNGNMEIGHIMALV
                     EYCILILFYLIMGVMVFMYIPRAGACADRVNQILDIEPEIVDGNGHKDTVSERGHLVF
                     KNVTFSYAQSEEPVLNNITFEAKSGEVTAIIGSTGSGKSTIANIIPRFFEIQSGEISI
                     NGQDIKKIPQKELRDKIGFVPQKAFLFSGTIEENIRYGKEDASIEEVKHAASIAQADE
                     FISDMEDKYDSFVAQGGNNLSGGQKQRISIARALVRKPEVYVFDDSVSALDFKTDKRL
                     RKALKNEIKDSSAIIIAQRISTIMDANQIIVLNDGKIVGIGKHKDLLENCEVYKQIAD
                     SQLSKEELA"
     gene            4045..5907
                     /locus_tag="KOU88_003280"
     CDS             4045..5907
                     /locus_tag="KOU88_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213134.1"
                     /translation="MSEKRIDEQDIEVLSFEDGMSAEKAKDAKKTTKRLLKYMAKQKF
                     KILIIFISVLISSALTVLAPMVMGKAIDQLFNGIKTAVQTGTKFSVNFSTMGGIVSIL
                     LGLYLISAVFIYIQQYIMSGVAQNLVLSMRKDLSDKLNKLPLKYYDSHKKGETLSIVT
                     NDLEKVADSLQEGLMQLITAVVTVVGSIVMMISISVPLTIVSAITLLVSLGITVVIAR
                     KSQERFSENQKALGELNSNIEEIFTGQIVVKAFSKEKDTIRNFKILNQNLYNASRKAQ
                     FSSYAISPIIRFINLIGYVIIAVVGGIFASTGAMTLGSIQAFIQYVNQASEPTTEISY
                     IVNMLQAAIASAERVFTVMDEVEEIKDEESSKVISMPKGKVQFEHVKFGYSDDFILMK
                     DININLNAGDKIAIVGPTGAGKTTLVNLLMRFYEIQGGRITIDGVNIKDLKRGELRTM
                     FGMVLQDTWLFNGSIKENIAYSKSDATMDEIVRAAKSARVDHFIRTLPQGYDTILTED
                     ASNLSQGQKQLLTIARAILSDPSVLILDEATSSVDTRTEVEIQKAMNNLMKGRTSFVI
                     AHRLSTIRDADLILVMKEGTIIEQGSHKELIEKKGFYEELYNSQFTSEYDEDVV"
     gene            6240..6929
                     /locus_tag="KOU88_003281"
     CDS             6240..6929
                     /locus_tag="KOU88_003281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="HBK3213135.1"
                     /translation="MNKKLNYRFEMKHKITEADVLALKSRLYPIMKKDENASKDGKYL
                     IRSLYFDTPEDKALLDKLNGVAIREKFRIRFYNNDCSYIRLEKKIKHYNMTSKLSTNL
                     TKKEVINILNNDIEFLKESTNCLLREFYLKLKCERLEAKSIVDYNREAFIYPVGNVRV
                     TIDSDIKTSVNSVDLFNKDLPTISVIDENMTVLEVKYDEFIPDFIKDLIQINKTTSTA
                     VSKYASSRLYI"
     gene            7034..7720
                     /locus_tag="KOU88_003282"
     CDS             7034..7720
                     /locus_tag="KOU88_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4956 domain-containing protein"
                     /protein_id="HBK3213136.1"
                     /translation="MILIMTFNDIFKSSFIENVSGFSFVDSALALGSAFLVGLFIYMV
                     YKKTYMGIMYSRPFNVSLVALTMLTTFVILAVTSNVVLSLGMVGALSIVRFRTAIKDP
                     MDLVFLFWSLGSGIVLGAGLIPLAVMGSIIMGLILIFFSNKTISETPYILMVNCNNED
                     SEDIATDKIKKVFTKYQIKSKSVTPEKGIELVFEVRMKDGETSLINDLSQVDGVTNAV
                     LVSYNGDYVA"
     gene            7737..9644
                     /locus_tag="KOU88_003283"
     CDS             7737..9644
                     /locus_tag="KOU88_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CotH kinase family protein"
                     /protein_id="HBK3213137.1"
                     /translation="MKDKKFTLLISIMIIFLCAVVGVYSTSSNKSADLYSDVYIEKYF
                     NRDKVMEVNIEIDESDLKDMNENAIKEEFKVAKVTVDGDTYGNVGIRTKGNSSLISVA
                     NSDSDRYSYKINFDKYNTSQSMEGLTQLNLNNCYSDPSYMREFLTYSICEEMGLATPE
                     FAYAKVSINGEYHGLYLAVEGLKESYLENNFGNVTGDLYKSDEGSSLQYKGDDPESYS
                     NLIVESDKKTADWSKITKLLKSLDIGEDIEKYLDVDSVLKNIAINTALLNLDSYQGSF
                     AHNYYLYEQDGVFSMLPWDFNMSFGGFSGFGGGSQSIAIDEPTTGNLEDRPLISSLLK
                     NETYKTKYHKYLEEIVTKYLDSDYLENMTTKLHDMIASYVKEDPTAFYTYEEFEKNIT
                     SSIEDSSDNKGFGNKGFDNNNSNNSDSNNNSNSENKRSGNQSDEKEVNAELTSSVVKA
                     NTDNETKNKTTNDSESKNNTDKDKSGNDNNQKLEGPMGKGGKSIPGVLEVAEDMSKTI
                     KSQLSGETSSTKQNSGDESSSGIKGSEKFDEDMSGMPEPPEGMDGKMPPGMGNMDKGD
                     MNGKNGNMNMDRNQDNPREAGGFGNRGGGSVSKTTTYFKLILGGASMIIMSIMLVGVS
                     RVKRRRFIKSK"
     gene            10097..10786
                     /locus_tag="KOU88_003284"
     CDS             10097..10786
                     /locus_tag="KOU88_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213138.1"
                     /translation="MLQKVLWKFLKLVVGLFICSVGIVLTINCNLGLSPWDVFHQGLS
                     NHIGITIGTASIIVGSIVVIADVVLGENVGWGTVFNMLLIGFFMDLLLYSNLIPEADS
                     LFVGIIMLILGLVLLSVGMVFYMGSGLGSGPRDGLMVAIQKKTGKSLKLIRGTIEVGA
                     LIVGFLLGGKVGIGTIISAFGLGYFTQMVFGLFKLDCSKIKHRFIVDDIKFIKVYMSG
                     EKKAAVQNIVK"
     gene            11222..11761
                     /locus_tag="KOU88_003285"
     CDS             11222..11761
                     /locus_tag="KOU88_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007286148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213139.1"
                     /translation="MDIGEKIKRLRTEKQLTQEELANRCELSKGFISQLENNLTSPSI
                     ATLIDILEILGTNLREFFNEIDDERISFTKEDMFETEDEDLKYKLKWLIPNSQKNEME
                     PIIITLYPGGQYKEEKPHEGEEFGYVLAGSIYVHIGEKKNKVKKGESFYFRPKANHYI
                     SNEGKTTAKVIWVSTPPSF"
     gene            11780..12823
                     /locus_tag="KOU88_003286"
     CDS             11780..12823
                     /locus_tag="KOU88_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011721317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213140.1"
                     /translation="MVENIIELRDISKHYEELTVLDNFNLDIKKNEFLTLLGPSGCGK
                     TTTLKIIAGFEYADDGKVLFEGKEINNLPPYERQVNTVFQKYALFPHMDVYENVAFGL
                     KIKKTPKDVIDAKVKEVLKLVALEGFERRQVESLSGGQQQRIAIARALVNEPKVLLLD
                     EPLGALDLKLRQEMQIELKRIQKKLGITFVFVTHDQEEALTMSDTIVVMYKGKIQQMG
                     TPQDIYNEPKNSFVAKFIGESNIFDGIMIEDYKVNFCNRDFECVDKGFEKNENIEVVI
                     RPEDIKMVKPEEGMLKGKVTSTVFKGVHYEIELNENGRLWILHNTKNAEVGTELGMDI
                     YPEDIHIMRKENN"
     gene            12825..13661
                     /locus_tag="KOU88_003287"
     CDS             12825..13661
                     /locus_tag="KOU88_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213141.1"
                     /translation="MKRKSFLAYPYVVWSAIFVIIPLILVVFFSFTKESGGGYAFTLE
                     NYKEVIDPIYMKVFGRSILLAGGATLICLIVGYPVAYIISKARVSRRGSLILLFILPM
                     WMNFLLRTYAWVAILGKNGLLNTFLGWFGIQPLAILYTNFAILLGMVYNFLPFMVLPI
                     YTALSKMDNDLINAAHDLGANNMTVFRKIIFPLSLPGVMSGITMVFMPAVTTFAISRL
                     LGGGKIMLVGDLIEQQFTVVGDWNFGSAISIFMMIVILISMSIMSKFGDESDKEGGGL
                     LF"
     gene            13766..14440
                     /locus_tag="KOU88_003288"
     CDS             13766..14440
                     /locus_tag="KOU88_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213142.1"
                     /translation="MARWNGFTWKWYGQLLQNESIMSALYYTIVIAILASVISTIVGT
                     ISAIGIHKMRGKSKKLILNVNYLPILNTEIVTAVALMSLFVFVKMEFGFTTMLLAHIM
                     FCLPYVILSVLPKMKQLPDNIEDAAMDLGATPIYALRKVILPQIKPGIVSGFLIAFTM
                     SIDDFIISFFNAGNGVSNLSIEIYGMARRGIKPEINALSTIMFAVVLGLLLLANKKES
                     IVRGIK"
     gene            14440..15492
                     /locus_tag="KOU88_003289"
     CDS             14440..15492
                     /locus_tag="KOU88_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK3213143.1"
                     /translation="MIKFKKAISLIAVGMMTVTLFTGCNKATDSTKVLNVYNVGDYID
                     ESLIDKFEKETGIDVQYSTYDTNEMMYQKVKSGSTHYDLVFPSDYMVEKMKNEGLLEK
                     LDFKNIPNMKYLDKSFLNPVYDKTNEYSVAYMWGTLGILYNKKEVKDPMDSWNILWNP
                     KYKGNIMMFDSVRDTIGITLKKLGYSMNSVNPKEINEAKNLLMKQKDLVLAYVNDEGK
                     DRLLGGEVAMGMLYSGDAVTLMEQNPDLDYAIPKEGTNKWVDAMCVPTTAQNKKEAEL
                     FINFLLDPENAKVNAEYIGYSTPNTGALKLLDPEITQNPVAYPSKEVLDKCETFEDIG
                     ENIKLYDKAWIELKSK"
     gene            15722..16570
                     /locus_tag="KOU88_003290"
     CDS             15722..16570
                     /locus_tag="KOU88_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3213144.1"
                     /translation="MNRINKKIDLLILALLVFIFLIVGIVILSIRTENKLNVFIMLAI
                     IFFIIMLTYLSNSVVGLITSSIIIFMYTSYILYNNITHNMDVEFISYMWIIATPVSSI
                     IMGNLNKSINELQNTNKKLSEQYKELVTIDSETGLRNLKIFYNDVNMEISKSIRHNTD
                     FSLMIVKLPYYGNLQTIFGENKTNKIVKYIGSNIIECTRNEDIIYSLQKDMIGILMPN
                     TSLEGSKVVKDRIKKRIKELNLDLNNRGKYVNIDVKIAFLQYKSSFGDSINFKNIVEE
                     ELQYDV"
     gene            16560..18224
                     /locus_tag="KOU88_003291"
     CDS             16560..18224
                     /locus_tag="KOU88_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK3213145.1"
                     /translation="MMFKIFNKSLLKLVVVLSIVLTISNFSLSSYASEITSSTDKVLI
                     IYDSKKETAYNRDILNIMRTLLGRFSSDIELLKLSNYDGEINKNYYSHIFILGINENS
                     YNNDKNTKNLISSLNLYKGTICWLGYGIENLLEHKKYNLDYVGKTNNIVSVNYRGKSY
                     NLDEHYVFNIVESKDTSNKVIGSINDTLNKYPYIINDKNLFYVSKLDLDGVLFYIFCD
                     SLNDIFNIKTFDKGRIFVRIEDVHAFREPKNLVEIADYLSSKNIPFTIALIPAYVNPK
                     NHKVITLSESPEIVKAIKYMQDKGGTVILHGYTHQYKKEEVSGEGYEFWDGKKDEPLK
                     ENMKIFVKDRVLNGLRVCIENGIYPLAFEAPHYAMESEGYKELKKYFSTYIGQHQNND
                     KKFSTNTYPYIIRDTEEFNIFIPENLGYIDPEDKFTFQNIKENLNKLSIVRGFSGGFF
                     FHSYLNIEYLKNTIEYLEKQNIEFMNLRDFNNWVKVDEIQIRNNGDEIIVNYDKDLDE
                     LTKSDTRFKSISNISKILIFIVSISVLIFVIIFIYFKRIDKKKFLK"
     gene            18273..19529
                     /locus_tag="KOU88_003292"
     CDS             18273..19529
                     /locus_tag="KOU88_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003362983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3213146.1"
                     /translation="MRDLNVSEYLFVFSLFSIWSLLLINIILAMGGYIFYFKNFDKEI
                     KEIDEYPMISILVPAHNEAKVIGRTVESLLLLNYPKSKMELIVINDNSSDNSKEILEN
                     IKDRYNNYNFTIINTDSLTGGKGKSNALNIGYTISKGDFIAVYDADNTPDKNALRYLV
                     QTIVMNDELGAVIGKFRTRNKNKNLLTKFINIETLSFQWMSQAGRWQLFNLCTIPGTN
                     FILRRSIIEEIGGWDSKAIAEDTEISFRIYKLGYKIKLVPQSITWEQEPETVKVWIKQ
                     RTRWAKGNIYVLMKYIKNIFKQGRNKIVFDIAYFFSVYFLFLTSVIISDILFVLSISK
                     LVEISIPINFFLIWILSYLLFIIEVSISLTIEKGEATIENIFIVAIMYFTYSQLWLFV
                     AIKGMIEYLKDIIFKREVKWYKTERF"
     gene            19552..21633
                     /locus_tag="KOU88_003293"
     CDS             19552..21633
                     /locus_tag="KOU88_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBK3213147.1"
                     /translation="MKKFIISIISLVLFFSNISLIYKVNADETKVKNYKFERDITIDG
                     VIGSNSTFFEVNKNWDIEEVLLHLNFSKSQILNGDVSSLTVLINNVPIKSIKLNAKTN
                     YKNTLEVLVPKDYIIQGYNEIKIKTYKTISDKICQDDSNTGNWMVIHKESYISIRYKQ
                     KKVENSINEYPYPYAEIENNHKLDTTIVVPDNMTRGETTAVFNLASAFGKITKNDDLK
                     LDVKLYSEMKNWSDDNIIYIGKPENTAEEILDILSIKEQTLLSSNCIIKQVDSPYNKN
                     KKMMVVIGSNEDDLIKASNLLIENRLSNQVLSSSVLVNKETNIKINREQKLNLGHLTL
                     KDLGYSDFLLEGAFNQQALFDVKIPTGKVLDDGSKIILNLRYSDNLDFEKSLVTVSIN
                     DVIVGSKKLDRSHSNNDKLELKIPKDIDNKNYYQVKLTFNLSIKNSNCVTRESNNPWA
                     YVSNNSYLALSTKENETLSFENYPYPFVRDDEFNDLTVIMPDYSGSQAMTWMFRLGVT
                     LGANINSHNGNINVIRGKEFSDKYKDTNIVVFGVPHNNSVIKMLNNNLNIKFDKNYSN
                     FISNDKISFIDDYGKNISTIQLIKSPYNNQKNIMVISSMNEKNLYLGMDYLLNKSKVN
                     DLKGDTLIIDEYGEVEDLAYNLKPKKEVKDSSWNMSINKTTKVFLMISFITIIVVMIL
                     SMLYIKKYKRR"
     gene            21670..22755
                     /locus_tag="KOU88_003294"
     CDS             21670..22755
                     /locus_tag="KOU88_003294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBK3213148.1"
                     /translation="MRKYMNEFKLKRSILISLIILIFIFIVYFVSIELKDRSLVNNQY
                     KGKIKSANLSVDYEINQVMKDIDKLGLNTVNVPIIINVESINSDIMSIDNNSKEKAIK
                     LIKKLNKKGISTILEAYPWIENGKLYETDWNPINKKRFFYTWQNAILNELIIDVANPL
                     DVNVLNIGSNFVHLEEYQQNWGEIIDFVQSKFDGLVTYRTNWWYTKKDDLSSKLFYEQ
                     KLNNNFFDKLDFISIAAYFELSNKPVNTVDELISALHSSTVNNRGQNIKQEIYNLYKA
                     HRKPIFFGELGFSNRESASSQPWNHTPSKAVNGEEQARCFEAYKKVFENEDWINGFSV
                     FCVGKIDDEKNFYPSKESIKVIKSWYE"
     gene            22809..23933
                     /gene="wecB"
                     /locus_tag="KOU88_003295"
     CDS             22809..23933
                     /gene="wecB"
                     /locus_tag="KOU88_003295"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBK3213149.1"
                     /translation="MNDIKVMTVFGTRPEAIKVAPLIKELEKRENINSIVCVTAQHRE
                     MLDQVIETFNINVDYDLDIMEKGQSLNDITCKILNKLPLILNKENPNIILVHGDTTTT
                     LATSLTAFYNKTLVGHIEAGLRTYDKHSPFPEELNRQLTGIIADMHFAPTNLARKNLI
                     SEGKPNNNIFVTGNTAIDALKMTIKENYNHPIIDEIGNDRMILLTSHRRENLGKPMKN
                     IFRAIKRIVDDFEDVQIVYPIHLNPKIRTIADEIFGKFPEKIHIIEPLDVADFHNFLN
                     KSYMIMTDSGGIQEEAPSLGKPVLVLRDKTERTEGIEAKTLKLVGTNEDRIYNSVSDL
                     LINKDNYVQMSKASNPYGDGNASKYIVDIIIKKFNCKYLN"
     gene            24011..24985
                     /locus_tag="KOU88_003296"
     CDS             24011..24985
                     /locus_tag="KOU88_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBK3213150.1"
                     /translation="MARKLIKNLGKSKSVKRVKLLFKKIFITVFIVASIVAIFNITKY
                     FEELYKVRDLKSTKIEYYMDVADEAGDGKVQLSWKALLAIDMVIHDEDLSNIKKKDTL
                     DIGEKFIVEDKNDKGEKVYKVKKFNKVLSELKFDSSQKSRARKYMKDLEYTYLGNKQL
                     DSSDEKIKFIKKLEDSAIREYIDYGILPSITIGQAILESGWGNSKLTKQSNNLFGIKA
                     DKAWKGKSVEISTSEHYNEKIVASFRSYNSLQDSVKDHSLFLINNKRYRKHGLFEAKD
                     YISQAQSLENAGYSTAEDKKGNRIYAELLIDVIRSYNLQLIDNKVETK"
BASE COUNT        10006 a         2504 c         4321 g         8297 t
ORIGIN      
        1 ttttatatat taattttatt gtcttttatt tatttaaatt tattatagat aaaactaaac
       61 tatctatgaa atatgaacta cttgaaaaag aaataattca taaggaagaa ttaagactta
      121 gtaatgagtg ttataaaatt attgttgaac agactgattc tgtcgttttc gaatggaata
      181 tcaaagaaaa taaatcattt gtatcgcagg cttggactga aaaatttgga tataacaatg
      241 catgtaagaa tatttttaaa gaaattaaag ataaagactt agttcattct gaagataaag
      301 ctatatttga aggttttctt gaaagtatta aaaaaaagaa tatgcacaat caagcagtat
      361 atcgtttaaa aaaatctaat ggtgaatata tttggtgtag aacatcaatt acaagcattt
      421 ataatgatga aaatgaactt ttaagagttg tcggagtaat tgtagatgta gatagtgata
      481 taaaaaaata tgaagagtta agaactagag cagaaagtga ctcattgacc aatatataca
      541 ataaaggtac atttgaaaaa ttagtggaag aaactatagt tatgaataca ggtgataaaa
      601 aagatgcatt attcattatt gatttggatg attttaaaga aataaatgat aattttggtc
      661 atccatttgg tgattttgta ctaaaaacat ttgctgataa gatacaaact agttttggta
      721 gtaaagactt agtcggaaga attggtggag atgaatttgt tgtatatatg caagattatg
      781 ttacagaagt aaatttgcat aaaaaagcta aagaattaaa tagagtactt tcggataatt
      841 acactgattt gagttttagt tttgatgctt ctgtcagtat aggtattgca aggtatcctc
      901 aagatggaac ttcatttttt gaattgttta aaaatgcaga tagagcactt tatagcataa
      961 aagcatcagg taaaaattca tattgtttat ttgaagaaga actatatgta cagtgaattt
     1021 gaatttagat tttatgtgag agtaagattt atatatactt gtggctgtct gatttataaa
     1081 atatgttact ttgtatattt ttatatgttt cagtaaggtt aattaacata agcaaaggtg
     1141 taagtaaatt tatattagtt taagtttact tacaccttta taaaaataca aataatagat
     1201 tcatttacat tcttaaatga ttaaagctct ttaccttcta aacatgcata acatatcgtt
     1261 ataattccag taaataagac taaaatgcca ttcctaagat tacagtttca tcatctatta
     1321 ctccaaatgt ttttaaagta acttatttcg ctttgtatca taataattta tctcctttta
     1381 cattttaact tctgctgaga tttgagttag atattcgtta gaatctcgca cacttatatc
     1441 atatagaaga tattcttcat aaacaaaatc cccaatacgt aaattattct gattaaaaaa
     1501 atttaataac ttttcataag tcttgtaaat agtttcataa ctccctttat gataagcagt
     1561 tacataaagt ccctttggtt tgattgatac aggatatttc ttgtactctt tattaacttt
     1621 tgtaaataaa tatgaatatg attcaaagtc tttattaatt atatcttcac ctttaatgat
     1681 tgagccaatc gtaccataat cactcaattc atagttgtcc ataaagttaa tacattcata
     1741 taaaaaattt tcttcctcat ctcctaaaaa ttgttcttta tatgtaacag gtgttttgac
     1801 caagtactct tcttcatgtt cttttaaagt aatagtattc gcatctatat tacaggcatt
     1861 tttagtgaat gaaatagtag attccattag agcttgaata ttatttagtt tttcaatttc
     1921 atttttaata tcaatggttt tcttttctaa aagctcaatt agtaaattag gtgttctttt
     1981 gtctatataa gctttaattt cttttaaagg catttttact tccctaagtg aagaaattat
     2041 accaaaaatg ctaagttgat ggtatgagta gtatctatat ccattttctt tctttaattc
     2101 tggtgagaaa agacctatat catcataatg gaaaagtgtt tttttattga ttccacaaat
     2161 ctttgcaaat tctccagttg taaaataatt ttttgaaact tgactcataa ttataattcc
     2221 tccttgacta tcctgttaca gtatagttta tcatagtatt ttgtaaagga gtgtgattat
     2281 atgaaaaaat taattcattt tttaaaacca tatagagttt taattgttgt agttttgata
     2341 tttacgtttt tacaaacact tggaactttg tatataccaa cacttacagc aaatatagta
     2401 aataatggtg tagtaaaggg agatatagat tatattgtaa aaacaggttt aatgatgatg
     2461 atagtagctg gtataacagc tttatcagct gtgttagttt gtaaagtatc agcaaatctt
     2521 tcatctggat tttgtagaga tattagagaa gcagtattta taaaatcaca agatttatca
     2581 ataaatgatt ttaataatat aggtacagca tcaatgatta ctaggagtac tagtgatatt
     2641 actttaatag gtcagtctgt gtttatgttt attcaattgg tattaccagc accaattata
     2701 actgtttctg gtctattctt agcatattct atagataaag caatgacaat tattattgtt
     2761 gtagtaatgt ttttattcat gctttcagca tttttagttg gtaaaaagct tataaagttg
     2821 tttaaaatga tgcaaataaa gatggacaat atgaataggg tgttacgtga ggtagtaact
     2881 ggagtaagag ttataagagc ttttaatagg agtcgttttg aaaaaaagag atttgataga
     2941 actgcaatag attattctga aacagcaatt tcaataaata aaatatttgc agtacttatg
     3001 cctattgtaa tgttaataat gaatttaggt atagtaagta ttatttggtt tggtgggatg
     3061 agggtcagta atggaaatat ggaaataggt catataatgg cacttgttga atattgtatc
     3121 ttaattttat tctatttaat catgggagta atggtattta tgtacatacc tagagcaggt
     3181 gcatgtgcag atagagtaaa tcagatatta gatatagaac ctgaaattgt agatggaaat
     3241 ggtcataaag atactgtctc agagagagga catttagtat ttaaaaatgt aaccttttca
     3301 tatgcacaat cagaagaacc tgtgttaaat aatataacat ttgaagcaaa atctggagaa
     3361 gtaactgcaa ttataggaag cactggctca ggcaaatcta ctattgcaaa tataatacca
     3421 cgtttttttg aaattcaatc tggagaaata tctataaatg gtcaggatat taagaagatt
     3481 cctcaaaaag aacttagaga taagattgga tttgtaccac aaaaagcttt tttatttagt
     3541 ggaacaatag aagaaaatat aaggtatgga aaagaagatg caagtattga agaagtaaag
     3601 catgctgcaa gtatagctca agctgatgaa tttatttctg atatggaaga caagtatgac
     3661 tcatttgtag cacaaggtgg aaataatttg tcaggtggtc aaaaacagag aatatccatt
     3721 gcaagagcgt tagttagaaa gcctgaagta tatgtctttg atgatagtgt ttctgcatta
     3781 gattttaaaa cagataaaag acttagaaaa gcgttgaaaa atgaaatcaa agattcatca
     3841 gctataatta tagcacaacg tataagtaca atcatggatg ctaatcagat tatagtttta
     3901 aatgatggaa aaattgtagg tattggaaaa cataaagatt tacttgaaaa ttgtgaagtt
     3961 tataagcaaa ttgcggattc acaacttagt aaagaagaac ttgcataaaa tgaagaatta
     4021 atctgatatt tggaggtgta tgatatgagt gaaaaaagaa tagatgaaca agatatagaa
     4081 gtacttagtt ttgaagatgg catgtcagca gaaaaagcta aggatgcaaa aaaaactact
     4141 aagagattat taaaatatat ggcaaaacaa aagtttaaaa tattaattat ttttatttca
     4201 gtattgataa gttcagcgct tacagtttta gcacctatgg ttatgggaaa agctattgac
     4261 caactattta atggaataaa aactgcagtc caaacaggta caaaattcag tgtgaatttt
     4321 agtactatgg gagggatagt atcaatactt ctagggttgt acttaattag tgcagtattt
     4381 atatatattc aacagtatat tatgtcagga gttgcacaaa atctagttct tagcatgaga
     4441 aaagatttaa gtgataaact caataaactt cctcttaagt actatgattc tcataaaaag
     4501 ggggaaacac ttagtatagt aacaaatgat ttagaaaaag tagcagatag tttacaagaa
     4561 ggattaatgc aacttattac agcagtagtt acagtagttg gttctattgt aatgatgata
     4621 agtataagtg taccacttac aatagtatca gctataacat tacttgtttc attgggtatt
     4681 actgttgtaa ttgcaagaaa atcacaagaa agattctctg aaaatcaaaa ggcactagga
     4741 gagttaaata gcaatataga agagatattt actggtcaaa tagtggttaa agcatttagt
     4801 aaagaaaagg atactataag aaactttaaa atattaaatc aaaatcttta taatgcaagt
     4861 agaaaagcac agttttcgtc atatgcaata tctccaatta ttagatttat aaacctaatt
     4921 ggctatgtta ttatagcagt tgtaggtggg atatttgcat caactggagc aatgactctt
     4981 ggtagtatac aagcgtttat tcaatatgta aatcaagcat cagagcctac tacagaaata
     5041 tcttatattg taaatatgct tcaagcagca atagcatctg cagagagagt ttttacagtt
     5101 atggacgagg tggaagagat aaaggatgaa gaatcttcaa aggttattag catgcctaaa
     5161 ggtaaagtac aatttgagca tgttaaattt ggatatagtg atgattttat tcttatgaaa
     5221 gatattaata tcaatctaaa tgcaggagat aagattgcaa ttgttggacc tacaggagct
     5281 ggaaagacaa ctcttgtaaa tttacttatg agattttatg agatacaagg tggaagaatt
     5341 actattgatg gtgttaatat aaaagattta aagcgtggag aacttagaac tatgtttggt
     5401 atggttcttc aagatacatg gctgtttaat ggaagtataa aagaaaatat tgcatatagt
     5461 aagtcagatg ccacaatgga tgaaattgta agagcagcaa aatcagcaag agtagaccat
     5521 tttataagga ctttaccaca agggtatgac actatattga ctgaggatgc ttctaatcta
     5581 tctcaaggtc aaaagcaact tctaacaatt gccagggcaa tactttcaga cccatcagta
     5641 ttgattcttg atgaagcaac atctagtgta gatactagaa cagaggtaga aattcaaaag
     5701 gcaatgaata acttgatgaa gggaagaact agttttgtta ttgcacatag attatcaact
     5761 attcgagatg ctgatttaat attagtaatg aaagaaggaa ctattattga acaaggaagc
     5821 cataaggaac ttattgaaaa gaaaggattc tatgaagaac tttataacag tcaatttaca
     5881 agtgaatatg atgaagatgt tgtatgatta tcaagtttta ggcaactaaa tgattgataa
     5941 atattaagtt aaatatagta acatgtaagg ttatatggaa taagagtatt tctctatttc
     6001 atataacctt ttttatttat caaaataaga taaaatttcc tttctaaatt agattgaaga
     6061 atgtatttat caatataaaa gtaaaataat cattattatt agtgaagtaa atattgtttg
     6121 ccacatatat gccataaaga tgcacttatt ttacggagat ttaacaaagt agtgtaaagt
     6181 atactctaaa tataaaataa atcaaataga gttaaataaa ttgagaggtg atataaatag
     6241 tgaataaaaa attgaactat agatttgaaa tgaagcacaa aataactgaa gcagatgtgt
     6301 tagctttaaa atcaagactc tatccaataa tgaagaaaga tgaaaatgca tctaaagatg
     6361 gaaaatatct tattaggagt ttatattttg atactcctga agataaagca cttttggata
     6421 aattaaatgg cgttgcaata agagaaaagt ttaggataag attttataat aatgactgct
     6481 cttatataag gttagagaaa aaaatcaaac attacaacat gacatcaaag ctatcaacta
     6541 atttaaccaa aaaagaagta ataaatatac taaataatga tattgaattt ctaaaagagt
     6601 cgacaaattg tttattaaga gaattttatt tgaaattaaa atgtgaaaga ttagaggcaa
     6661 aaagcatagt tgattacaat agagaagctt ttatttatcc agttggaaat gtaagagtta
     6721 caatcgatag tgatattaaa acttctgtaa attcggtaga tttatttaat aaagatttgc
     6781 caactatttc ggtaattgat gagaatatga ctgtattgga ggttaaatat gatgaattta
     6841 taccagattt tataaaggat ttaattcaaa ttaataagac tacctctaca gcagtttcaa
     6901 agtatgcttc aagtagatta tatatttaag aataaaggct atgatttata taaagatata
     6961 cataaataag gttaaaaaac aaataagtta aaaataaata aaataaaaaa taaataagtt
     7021 aaaaatagga aggatgattt taattatgac atttaatgat atttttaaat caagttttat
     7081 agaaaacgta tcaggttttt catttgtgga cagtgcttta gcactaggtt cagctttttt
     7141 agtaggtttg tttatatata tggtctataa aaagacttat atgggaatta tgtattctcg
     7201 accattcaat gtgtcgcttg tagcacttac aatgcttaca acttttgtaa tattggcggt
     7261 tacttcaaat gtagttttat ccttaggtat ggttggtgct ttatctatag taagatttag
     7321 aacagcaatt aaagacccaa tggatttagt atttctattt tggtcattag gttcaggtat
     7381 agttttagga gcaggtttga ttcccttagc tgtcatgggt tcaataatta tgggattgat
     7441 tctaatattc ttttcaaata aaacaatatc tgaaactcca tatatattga tggtaaattg
     7501 taataatgaa gattcagaag atatagcaac tgataaaatt aaaaaagtat ttactaaata
     7561 tcaaataaaa tcaaaaagtg ttacaccaga aaaaggaata gaattagtgt ttgaagtaag
     7621 aatgaaagat ggagaaacaa gtcttataaa tgacttgagt caagtagatg gagttactaa
     7681 tgcagttctt gtaagttata atggtgacta tgtagcatag agaggagtaa tcttttatga
     7741 aagataaaaa atttaccctt cttatctcga ttatgattat atttttatgt gctgtagttg
     7801 gagtttatag tacatctagc aacaaaagtg ctgatttata tagtgatgta tatattgaaa
     7861 aatattttaa cagagacaag gttatggaag ttaatataga gatagatgaa agtgacttga
     7921 aggatatgaa tgaaaatgct ataaaagaag aatttaaggt tgcaaaagta actgtagatg
     7981 gagatacata tggaaacgta ggtataagaa ctaaaggaaa ttcaagtctt atatctgtag
     8041 caaatagtga tagtgataga tacagctata agattaattt tgataagtat aatactagtc
     8101 aaagtatgga agggcttact caattaaatc ttaataactg ttactctgac ccatcttata
     8161 tgagagagtt tttaacatat agtatttgcg aggaaatggg attagcgact ccagaatttg
     8221 catatgctaa agtctctata aatggcgaat atcatggttt gtatttggca gtagaaggat
     8281 taaaagagtc ttatcttgaa aataattttg gtaatgtaac tggagactta tataagtcag
     8341 atgaaggaag ctcgttgcaa tataaaggag atgacccaga aagttactca aacttaatcg
     8401 ttgaaagtga taaaaagaca gctgattggt ctaaaatcac aaaactatta aaatctttgg
     8461 atataggtga agatattgaa aaatatcttg atgtagattc tgtccttaaa aatatagcaa
     8521 taaatacagc tttattaaac cttgatagct atcaagggag ttttgcccat aactattatt
     8581 tatatgagca agatggagta ttttctatgt taccatggga ttttaatatg tcatttggtg
     8641 gatttagtgg ttttggtgga ggtagtcaat ctatagcaat tgatgaacct acgacaggta
     8701 atttagaaga cagacctctc atatcctcgt tattaaaaaa tgagacatac aaaacaaaat
     8761 accataaata tctggaagag atagtaacaa aatacctaga ttcagactat ttagagaata
     8821 tgacaacaaa attgcatgac atgatagcat catatgtaaa agaagaccca acagcatttt
     8881 atacttatga agaatttgaa aaaaatataa catcttcaat tgaagattct agtgataata
     8941 agggatttgg taataaaggg tttgacaaca ataactctaa taacagtgat tctaataata
     9001 attctaatag tgaaaataag cgctctggaa atcaaagtga tgaaaaagaa gttaatgctg
     9061 aattaacatc aagcgtagtc aaagctaata cagataatga aactaaaaat aaaactacaa
     9121 atgatagtga aagtaagaat aatacagata aagataaaag tggaaatgat aataatcaaa
     9181 agctagaagg tcctatgggt aaaggaggta agtcaatacc aggggttttg gaagttgcag
     9241 aagatatgag taaaactata aaatctcaat taagtggaga aacttcttcg acaaagcaaa
     9301 actctggtga tgaaagttca agtggaatta aaggtagtga aaagtttgat gaggatatga
     9361 gtggtatgcc agaaccacct gagggaatgg atggtaaaat gccaccagga atgggtaata
     9421 tggataaggg agatatgaat ggtaaaaatg gcaatatgaa tatggataga aatcaagata
     9481 atccaagaga agctggaggt tttggcaata gaggaggagg ctctgtgagt aaaacaacaa
     9541 catacttcaa attaatttta ggtggagctt caatgataat aatgtcgatt atgttagttg
     9601 gtgtatcaag ggtaaagaga agaagattta taaagtcaaa ataagattaa aattgaatat
     9661 aaataatttt aatactgtta agtctaaata tttacttagc agtatttttt tagaaaataa
     9721 tgtatttggt taataatata aggtaataaa ttgataaaaa ttaaatacag catattaata
     9781 atacataata aagtaataaa aaaactgttt aagtataata acttatattt agacagtttt
     9841 tttcatttat aaataatata aatgaaattg aaaacatttg aaggatagaa attggttgga
     9901 taaatgtata aattacttca ccaaaaaata atgacaaaaa ttgtaactaa gttgtaataa
     9961 aatggtagtt atttagcata aaataatgta tcatagaagt atattataaa attaataaaa
    10021 taagattttt gtaagaaaac tgctggcttt tgatatttag agtgagtagt taaattatgt
    10081 ttaggagggg tagaatttgt tgcaaaaagt attatggaaa tttttaaagc tagtagtcgg
    10141 tttatttata tgttcagttg gtatagtatt gacgataaat tgtaaccttg gattatctcc
    10201 ctgggatgta tttcatcaag gactttcaaa tcatatagga ataactatag gaactgcttc
    10261 tataattgta ggctctatag tagttattgc tgatgtcgtt cttggagaaa atgtaggatg
    10321 gggaactgtt tttaacatgc tactaattgg attctttatg gatttacttt tatatagtaa
    10381 tttaattcca gaggctgata gtttatttgt aggaataatt atgttgatat taggattggt
    10441 tcttttgtct gttggaatgg tattttatat gggaagtggt ttaggaagtg gacctagaga
    10501 tggtttgatg gttgcaattc aaaagaaaac aggaaaatca cttaaattaa taagaggtac
    10561 tatagaagtt ggagcattaa tagtaggatt tttattaggt ggaaaagttg gtataggaac
    10621 tataataagt gcatttggat tggggtattt cacacaaatg gtatttggct tatttaaatt
    10681 agattgtagt aagattaaac atagatttat agtagatgat ataaaattta tcaaagtgta
    10741 tatgagtggt gagaaaaaag ctgctgttca aaatatagtt aagtaattta agaataaatt
    10801 caacgaaatg ttaagtattt taaattaaca ttttgtttag atagataaat tgaatattaa
    10861 aagaatatta aaatatgagg attgctagaa cactataaaa tatagatttc tagcaatttt
    10921 ttatttgttc aatatttttt tagtactaga agtcttattc tctatttaat gaatgaatta
    10981 atttataatt agagatacta aactttatag atattaatat aaacaccttt aaactgtgta
    11041 ttttccaaag cctttaaaat gcttgtattt attctaaata aaaaaataaa aaaatgtcaa
    11101 aaaaactctt gtattatatc caaattttat atataattac ctatgttgtt tagaaatttt
    11161 aaactcaatg tttagtaaac aaaatgttta gtaaaataaa acagaaacta ggaggtgcaa
    11221 catggatata ggtgaaaaga taaaaagatt aagaacagaa aaacaactga cccaggaaga
    11281 gttagctaat agatgtgaat tgtcaaaggg atttatttct caattagaaa ataacttaac
    11341 atcaccatcc atagctaccc ttatagatat acttgaaata ctaggtacaa atttaaggga
    11401 attttttaat gaaatagatg atgaaagaat cagttttaca aaagaagata tgtttgaaac
    11461 agaagatgaa gatttaaaat ataaattaaa gtggttaatt ccaaattcac aaaaaaatga
    11521 aatggagcca ataataataa cattgtatcc aggaggacag tataaagaag aaaagccaca
    11581 tgaaggtgaa gaatttggat atgtattagc aggttcaata tatgtccata taggcgaaaa
    11641 gaaaaataaa gtaaaaaaag gagagagttt ttactttaga ccgaaagcaa atcactatat
    11701 atcaaacgag ggcaaaacta cagcaaaagt gatttgggta agtacgccac catcatttta
    11761 gaatagaggt gtttaataat tggtagaaaa tataatagaa ttaagggata tatctaaaca
    11821 ttatgaagaa cttactgttt tagataattt caatttagat ataaagaaaa atgagtttct
    11881 aacattactt ggaccaagtg gatgtggaaa aactacaaca ttaaaaataa tagcaggatt
    11941 tgagtatgct gatgatggta aagttttatt tgaaggtaag gagataaata atttgccacc
    12001 atatgaaaga caagtaaaca cagtatttca aaaatatgct ttatttccac acatggatgt
    12061 ttatgaaaat gtagcttttg gattaaaaat taaaaagact ccaaaagatg taatagatgc
    12121 taaagtaaaa gaggttttga aacttgttgc actagaaggt tttgaaagac gacaagttga
    12181 atcattgagt ggaggacaac aacaaagaat tgcaatagca agagctctag ttaatgaacc
    12241 aaaggtatta ttactagatg aaccacttgg agcacttgat ttaaagttaa gacaagagat
    12301 gcaaatagaa ttaaagagaa tccaaaaaaa attaggaata acatttgttt ttgtaactca
    12361 tgaccaagaa gaggctctta ctatgtcaga tactattgtt gtaatgtata agggcaaaat
    12421 tcaacaaatg ggaacaccac aagatatata caatgaacct aaaaattcat ttgtagctaa
    12481 gtttataggt gaaagtaaca tatttgatgg aattatgata gaagattata aagttaattt
    12541 ctgtaataga gattttgagt gtgttgataa aggattcgaa aaaaacgaaa atatagaagt
    12601 agtaataaga ccagaagata taaaaatggt aaagccagaa gaaggaatgt taaaggggaa
    12661 agttacatct acagtgttta aaggagtgca ttacgagata gaattgaatg aaaatggaag
    12721 attgtggata cttcataata ctaaaaatgc tgaggttggg actgaactag gcatggatat
    12781 atatccagaa gatatccata taatgagaaa agagaataac taagatgaaa agaaaatctt
    12841 ttttagcata tccatatgta gtttggagtg cgatatttgt aataattcct ttaatattag
    12901 tagtattttt tagttttaca aaagaatcag gtggaggtta tgcctttaca cttgagaatt
    12961 ataaagaagt aattgaccct atatatatga aagtttttgg gcgttctatt cttttagcag
    13021 gaggagctac attaatatgc cttatagttg gttatccagt ggcatatata atttcaaagg
    13081 ctcgtgtaag tagaagaggt tcattaatat tattgtttat tcttcctatg tggatgaact
    13141 ttcttttaag aacatatgca tgggttgcta tattaggaaa aaatggactt ttaaatacat
    13201 ttttaggttg gtttggaata caaccattag caattttgta tactaatttt gccatacttt
    13261 taggtatggt gtataacttt ttaccattta tggttcttcc aatatataca gcactatcaa
    13321 agatggataa tgatttgata aacgctgctc atgacttggg tgcaaataat atgacagttt
    13381 ttagaaaaat tatatttcct ttgagtttgc caggtgtaat gtctggaata actatggtat
    13441 ttatgccagc agtcactact tttgcaatat caagactgtt aggtggaggt aaaataatgc
    13501 tggttggaga tttgattgaa caacagttta cagttgttgg agattggaac tttggttcag
    13561 ctatatcgat atttatgatg atagtaatat taatatctat gtctataatg tcaaaatttg
    13621 gagatgaatc tgacaaagaa ggcggtgggt tactatttta aaattaaaga aaataacttc
    13681 taatatatat ttagcattag tattcttatt tttgtatgca cccatatttg ctttggtact
    13741 attttctttc aatgattcaa aatcaatggc aagatggaat ggatttacat ggaagtggta
    13801 tggtcaatta cttcaaaatg agagtataat gagtgcttta tattatacta ttgtaatagc
    13861 tatattagcg tctgtaatat ctacaatagt aggaactata agtgctatag gaatacataa
    13921 gatgagaggt aagagtaaga aattaatact aaatgtaaac tatcttccta ttttaaatac
    13981 agagatagtt acagcagtag ctcttatgag tctgtttgta tttgtaaaaa tggaatttgg
    14041 atttacaaca atgctattgg cacatataat gttttgtttg ccatacgtta tactttcagt
    14101 tttgccaaaa atgaagcaat tacctgataa tatagaagat gcagctatgg acttgggagc
    14161 aacacctata tacgctctta gaaaagtaat tttaccacaa ataaaaccag gtatagtttc
    14221 tggattttta attgcattta ctatgtcaat agatgacttt ataataagtt tctttaatgc
    14281 tggaaatggt gtaagcaatc tttctataga aatctatgga atggctagaa gaggtataaa
    14341 acctgaaata aatgcattat caacaataat gtttgcagtg gttctaggtt tacttttact
    14401 agctaataaa aaagaatcta tagtaagggg gattaaataa tgattaagtt taaaaaagca
    14461 atatccctta tagctgtagg tatgatgaca gttactttat ttacaggatg taataaagca
    14521 actgattcta caaaagtttt aaatgtatat aatgttggag attatataga tgagtctctt
    14581 atagataagt ttgaaaaaga aacaggaata gatgttcaat attcaactta tgatactaat
    14641 gaaatgatgt atcaaaaagt aaagagtggt agtacacact atgatttagt atttccttca
    14701 gactatatgg tagagaaaat gaaaaatgaa ggtcttttgg aaaaattaga ttttaagaat
    14761 atacctaata tgaaatattt agataagagt tttttaaatc ctgtatacga caaaactaat
    14821 gaatatagtg ttgcatatat gtggggaact cttggaatac tgtacaataa gaaagaagtt
    14881 aaagacccta tggatagctg gaatatactt tggaatccaa agtataaggg aaatataatg
    14941 atgtttgact ctgttagaga tactataggg ataactctta aaaaattagg atatagcatg
    15001 aatagtgtaa atccaaaaga aataaatgaa gctaaaaatc ttttaatgaa acaaaaggat
    15061 ttagtattgg cttatgtaaa tgatgaaggt aaggatagat tgcttggtgg agaagtggca
    15121 atgggtatgc tgtattctgg agatgcagtt acactaatgg agcaaaatcc tgaccttgat
    15181 tatgctatac ctaaagaggg aactaataaa tgggtagatg ctatgtgtgt acctacaaca
    15241 gcacaaaata agaaagaagc tgagctgttt ataaactttt tattagaccc agagaatgca
    15301 aaagtaaatg ctgagtacat tgggtattca acacctaata caggagcact aaaattatta
    15361 gacccagaaa taactcagaa tcctgttgca tatccatcta aagaagtgct tgataaatgt
    15421 gaaacttttg aagatattgg tgaaaatata aaattatatg acaaggcttg gatagagtta
    15481 aaatcaaaat agggtcttgt tggtttaagt aaatttactt aataaatact taataaaact
    15541 gttctttttt agaaaattta ttttctaatt attgaacagt tttatttttt gtttaagtta
    15601 tattcatatg caatttaaat agtttattaa taaatgaaaa cttatttgta taatgacttt
    15661 aataataatt agaaaaaatg ggcaacttaa tagaataatt ggaggtgtaa atttataaaa
    15721 aatgaatagg ataaataaaa aaatagattt attaatattg gctttgctcg tttttatatt
    15781 tttaattgtt ggaatagtaa tactatcgat taggacagaa aataaattga atgtgttcat
    15841 aatgttagca ataatttttt ttataataat gttaacttat ttatcaaatt cagtagtggg
    15901 gttgataaca agttcaataa ttatatttat gtatacatcc tatattttat ataacaatat
    15961 tactcacaat atggatgttg aatttatatc atatatgtgg ataatagcaa caccagtatc
    16021 ttcaattata atgggtaatc tgaacaaaag cataaatgaa ttgcaaaata caaataaaaa
    16081 actatctgaa cagtataagg aattagtgac tattgatagt gaaactggac ttagaaattt
    16141 aaagattttt tataatgatg taaatatgga gataagtaaa tctattagac ataatactga
    16201 tttttctctt atgatagtaa aattaccata ctacggaaac ctacagacta tatttggtga
    16261 aaacaaaact aataaaatag taaaatatat tggttcaaat attatagaat gtacaagaaa
    16321 tgaagatata atttatagtt tacaaaaaga tatgataggg atactaatgc caaatacatc
    16381 tttggaaggt tcaaaagttg ttaaagacag aataaagaaa aggataaaag aattaaattt
    16441 agatttaaac aataggggaa aatatgtaaa tatagatgtc aaaattgcat ttttacaata
    16501 taagagtagt tttggagata gtataaattt taagaatata gttgaagagg aacttcaata
    16561 tgatgtttaa aatatttaat aaaagtctat taaaattagt agttgtatta tcaatagtac
    16621 tgacaatatc aaattttagc ttatcttcat atgcatcaga aattacttcc agcacagata
    16681 aggtattaat catatatgat tctaagaaag aaacagctta taatagagat attttaaata
    16741 ttatgaggac tctattggga agatttagtt cagatataga gctattaaaa ttgagtaact
    16801 atgatggtga gataaataaa aattattaca gtcatatatt tattttagga atcaatgaaa
    16861 actcatataa taatgataaa aacactaaaa acttgattag ttccttaaat ttatataaag
    16921 gaactatatg ttggttagga tatggtatag aaaatctttt ggaacataaa aaatacaatt
    16981 tagactatgt aggaaaaaca aacaatatag ttagtgtaaa ttatagaggt aaatcatata
    17041 acttggatga acattatgtt tttaacattg tagaatcaaa agatacaagt aataaagtaa
    17101 taggaagtat taatgatacc ttaaataagt atccatatat aataaatgat aaaaatcttt
    17161 tttatgtatc aaaattagat ttagatggag ttttatttta tatattttgc gattcactta
    17221 atgatatttt taatattaag acgtttgata aaggacgtat atttgtaaga atagaagatg
    17281 tacatgcttt tagagaacca aaaaatcttg tagagatagc ggattattta agtagtaaga
    17341 atataccatt tacgattgca ttaataccag catatgtaaa tcctaaaaat cataaggtaa
    17401 taactttatc agaaagccct gaaattgtca aagcaataaa atatatgcaa gataaaggtg
    17461 gaactgtgat attgcatgga tatactcatc aatacaagaa agaagaagtt tctggagaag
    17521 ggtatgaatt ttgggatggt aaaaaagatg aacccttaaa agaaaatatg aagatatttg
    17581 tcaaagatag agttttgaat ggtcttagag tatgtataga gaatggaatt tatcctcttg
    17641 catttgaagc gccacattat gcaatggaat cagagggata taaagaatta aaaaaatatt
    17701 tttctactta tatagggcaa catcaaaata atgataaaaa atttagcaca aatacatatc
    17761 cttatattat tagggataca gaggagttta atatatttat acccgaaaat ttaggatata
    17821 tagacccaga agataagttt acttttcaaa atataaaaga aaatttaaat aaattatcca
    17881 ttgtaagagg ttttagtgga gggttcttct ttcattcata tttaaacata gagtatctaa
    17941 aaaacacaat agaatattta gaaaaacaga atatagaatt tatgaattta agagatttta
    18001 ataattgggt aaaagttgat gaaatacaaa taagaaataa tggagatgaa attatagtca
    18061 actatgataa ggacttagat gaactaacta aaagtgatac tagatttaaa tccatatcca
    18121 atattagtaa aattttaata ttcatagtat ctataagtgt tttaatattt gtgattatat
    18181 ttatatattt taagagaata gataaaaaga aatttttaaa ataaatgatt ttatattaga
    18241 atcaatattt taaaatattt taggagaaat ttatgagaga tttaaatgta tcagagtatt
    18301 tgttcgtatt tagtctgttt agtatatggt ctttattgct tataaatatt attttagcta
    18361 tgggtggata tatattttat tttaaaaact ttgataaaga aataaaagaa attgatgaat
    18421 atcctatgat atcaatactt gttcctgctc ataatgaagc taaagtgata ggtagaactg
    18481 tggagtcttt gctattactc aattatccta agagtaagat ggaacttatt gttataaatg
    18541 acaattcttc tgataatagt aaagaaattt tagaaaatat aaaggatagg tacaacaatt
    18601 ataatttcac tataataaat acagatagtt taacaggtgg aaaaggaaag tctaatgcat
    18661 taaatattgg atatacgatt tcaaaaggag attttatagc tgtttatgat gcagataaca
    18721 caccagataa aaatgcactt agatatctag tacaaactat agtaatgaat gatgaattag
    18781 gtgctgttat tgggaaattt aggactcgaa ataaaaataa aaacctatta accaaattta
    18841 taaatataga aacattaagc tttcaatgga tgtcacaagc tggtagatgg caacttttta
    18901 atctatgtac aataccagga actaacttta tattgaggag aagtatcata gaagaaattg
    18961 gaggatggga tagtaaagca attgcagaag atacagaaat aagttttagg atatataaat
    19021 tgggatacaa gataaagctt gtaccacaat ctataacatg ggaacaagag ccagaaactg
    19081 ttaaggtgtg gataaagcaa cgtactagat gggcaaaagg gaatatatat gtattaatga
    19141 aatatataaa aaatatattt aaacagggaa gaaataagat tgtgtttgat atagcttact
    19201 ttttttctgt atattttcta tttttaacat ctgtaattat atccgatatt ttatttgttt
    19261 taagtatatc taaactagta gaaatttcta ttccaattaa cttttttcta atatggatac
    19321 tatcttatct tttatttatt atagaagtga gtataagcct tactatagaa aaaggtgaag
    19381 caacaattga aaatatattc atagtggcaa taatgtattt tacatactct caactatggc
    19441 tgtttgtagc tataaaagga atgatagagt atctaaaaga tataattttt aaaagagagg
    19501 ttaaatggta taaaacagaa agattttgat tcatgtacag gaggaattaa catgaaaaaa
    19561 tttattatat caattatatc tttagtattg tttttttcaa atatatcact tatatacaaa
    19621 gtaaatgctg atgagactaa agttaaaaat tataagtttg aaagagatat aactattgat
    19681 ggtgttatag gaagtaatag tacttttttt gaagtaaata aaaattggga tattgaagaa
    19741 gttttattgc atcttaattt tagtaagagc caaatattaa atggagatgt ttcaagttta
    19801 actgtattga taaataatgt accaataaaa tctattaaat taaatgctaa gacaaattat
    19861 aaaaatacat tagaagtatt agttccaaaa gattatataa ttcaaggata taatgaaata
    19921 aaaataaaaa catacaaaac aatatctgat aaaatttgcc aagatgattc caatactggg
    19981 aactggatgg ttattcacaa agaatcatat atatcaatta gatataagca gaaaaaggtg
    20041 gaaaactcaa taaatgaata tccgtatcca tatgcagaaa ttgaaaataa tcataaatta
    20101 gatacaacta tagtagtacc agataatatg actagaggag agactacagc agtgtttaat
    20161 ttggcatcag catttggaaa aataacaaaa aatgatgatt taaagttaga tgttaaatta
    20221 tattcagaaa tgaaaaattg gtcagatgat aatattatat atattggtaa acctgaaaat
    20281 acagcagaag aaattttgga tattttaagt ataaaggaac aaaccctatt atcttcaaac
    20341 tgtataatca agcaagtaga ttcaccatac aataagaata agaagatgat ggtggtaatt
    20401 ggtagtaatg aagatgattt aataaaggca tcaaatttat taatagaaaa tagactttct
    20461 aaccaagttt tatcatcatc agtacttgta aacaaagaga ctaatataaa aattaatagg
    20521 gaacaaaaat taaatttagg tcatttaaca ttaaaagatt taggatattc tgactttttg
    20581 ttggaaggag catttaatca acaagctttg tttgatgtca aaataccaac gggtaaggta
    20641 ttagatgatg gttcaaagat tatcttaaat ttaagatatt ctgacaattt agattttgaa
    20701 aaatctttag ttacagtgtc tataaatgat gttattgtgg gaagtaaaaa attggatagg
    20761 tcacattcta ataatgataa gttagaatta aaaataccta aagatataga taataaaaac
    20821 tattatcaag ttaaattgac atttaatttg agtataaaaa attcgaattg tgttactaga
    20881 gagagtaata atccttgggc atatgtatca aataattctt atttggcgtt atctacgaaa
    20941 gaaaatgaaa ccttatcttt tgaaaattat ccgtatccat ttgttagaga tgatgaattt
    21001 aatgatttaa ctgtgataat gccagattat tcagggtcac aagctatgac ctggatgttt
    21061 agattaggtg ttactttagg tgcgaatata aattcacata atggaaatat aaatgtaatt
    21121 agaggaaaag aatttagtga caagtataag gatactaata ttgtagtttt tggagtgcca
    21181 cataataatt ctgttataaa gatgttaaat aataatttaa atataaagtt cgataaaaat
    21241 tactccaatt ttatatcaaa tgataagata agctttattg atgattatgg aaaaaatatt
    21301 tctaccattc aattaataaa atcaccatat aataatcaaa aaaatatcat ggtaattagt
    21361 tcaatgaatg aaaaaaactt atatttagga atggattatt tgttgaataa aagtaaagtt
    21421 aatgatttaa aaggagatac attgataatt gatgaatacg gagaggtaga agatttagct
    21481 tataatttaa aacctaagaa agaagtaaaa gattcaagct ggaatatgag tataaataag
    21541 acaactaaag tatttttaat gatttctttt attactataa ttgtagtcat gatattatca
    21601 atgctatata taaaaaaata taaaagaaga taatatgata aatttattat tttaaaagag
    21661 gtatataatt tgaggaaata tatgaatgaa tttaaattaa aaagaagtat tttaatctca
    21721 ttaataatct taatttttat atttatagtt tactttgtaa gtattgagtt aaaagatagg
    21781 agtctagtaa ataatcaata taaaggtaag attaaatcag ccaatttatc tgtagattat
    21841 gaaataaatc aagttatgaa ggatatagat aaattgggat tgaatacagt aaatgtacct
    21901 ataattataa atgtagagtc cattaattct gatattatgt caatagataa taatagtaaa
    21961 gaaaaggcaa ttaagttaat aaaaaaatta aataaaaaag gtatttcaac aatattagag
    22021 gcatatccat ggattgaaaa tggaaaattg tatgagactg actggaaccc tataaataaa
    22081 aaaagatttt tttatacttg gcaaaatgcc atattaaatg aacttataat tgatgtagca
    22141 aatccactgg atgtaaatgt tttaaatatt ggttctaatt ttgtacattt ggaagaatat
    22201 caacaaaatt ggggtgaaat aatagatttt gtacaatcca aatttgatgg tcttgtaacg
    22261 tacagaacta attggtggta tacaaaaaaa gatgatttaa gtagtaagtt gttttatgaa
    22321 caaaagttga acaataattt ttttgataag ttagatttta tatctatagc agcatatttt
    22381 gagttaagta ataaacctgt taatacagtg gatgaattaa tttctgcctt acactcatct
    22441 actgtaaaca atagaggaca aaatataaaa caagaaatat ataaccttta taaagctcat
    22501 agaaaaccta tattttttgg agaattaggt ttttcaaata gagaaagtgc aagttctcag
    22561 ccgtggaatc atactccttc aaaagctgta aatggcgaag aacaagcaag gtgttttgag
    22621 gcatataaga aagtttttga aaatgaagac tggataaatg gtttttctgt gttttgtgta
    22681 ggtaaaatag atgacgaaaa aaatttttac ccatcaaaag agagtataaa agttattaag
    22741 tcttggtatg aataattttg aaagtgtaga atttatatag attaaataga tgattaggag
    22801 agatataaat gaatgacatc aaggttatga ctgtatttgg aactagacct gaagctatca
    22861 aagtagcacc tttaataaag gaacttgaaa aaagagagaa tataaatagt attgtttgcg
    22921 ttacagctca acatagagaa atgcttgacc aagttataga aacctttaat ataaatgtag
    22981 actatgattt ggatataatg gaaaaaggac aaagcctgaa tgatataaca tgtaagattt
    23041 taaataaact tcccttgatt ttaaacaagg aaaatccaaa tataatattg gtacatggag
    23101 atacaaccac aactctagct acaagtttga ctgcatttta taataaaact cttgttggtc
    23161 atatagaagc tgggcttaga acctatgata aacattctcc ttttccagag gagttaaata
    23221 gacaacttac aggtattatt gctgatatgc actttgctcc tactaatttg gctagaaaaa
    23281 acttgatttc tgaaggaaaa cctaataata atatatttgt aactggtaat actgctattg
    23341 atgctttaaa gatgacaata aaagaaaact ataatcatcc tataattgat gagattggta
    23401 acgataggat gattttgtta acctctcaca gaagagaaaa tttgggtaaa cctatgaaaa
    23461 atatattcag agctataaag cgaatagtag atgactttga agatgtacag atagtatatc
    23521 ccatacattt aaatcctaaa atacgaacta tagctgatga gatatttgga aaatttcctg
    23581 aaaaaattca tattatagag cctttagatg tagctgattt tcataacttt ttaaataaat
    23641 cttatatgat aatgactgat agtggaggaa tacaggaaga agctccatca ttaggtaagc
    23701 cagttcttgt gttgcgtgat aaaacagaaa gaacagaagg aattgaagca aagacactta
    23761 aattagtagg tactaatgaa gatagaatat ataattcagt gagcgattta ttaataaata
    23821 aagataacta tgttcagatg agtaaagcat ctaatccata tggagatgga aatgcaagca
    23881 aatatatagt ggatataata attaaaaaat ttaattgcaa atatttaaat tagataaggc
    23941 ctaaaacatt aactaattga tataagattt atgataatat taaggaatac aatttttaag
    24001 ggggagtaat atggctagaa aattaataaa aaatttgggt aaaagtaaaa gtgtaaagag
    24061 agtgaaactt ttatttaaga agatttttat tactgtattc atagtagcaa gtatagttgc
    24121 tatttttaat ataacgaaat attttgagga attatacaaa gtaagggatt taaaaagtac
    24181 taaaattgaa tactatatgg atgtggctga tgaagcagga gatggaaagg tccaattaag
    24241 ttggaaggcc ttacttgcta tagacatggt aatacatgat gaagatttaa gtaatataaa
    24301 aaagaaagac acattggata taggggaaaa gtttatagta gaagataaaa atgataaagg
    24361 cgaaaaggtg tataaggtaa aaaagtttaa taaggtatta agcgaattga aatttgactc
    24421 ttctcaaaaa agtagagcaa gaaaatacat gaaagatttg gaatacacat accttggaaa
    24481 taaacaatta gatagtagtg atgaaaaaat taaatttata aagaagttag aagactcagc
    24541 tataagagaa tatattgatt atggaatatt gccctctata acaattggac aagctatatt
    24601 agaatctggt tggggaaatt ctaaacttac aaaacagagt aataatttat ttggtataaa
    24661 agcagataaa gcatggaaag gaaaaagtgt agaaatttca acttcagagc attataatga
    24721 aaaaattgta gctagtttta ggtcgtataa ttcattacaa gattctgtca aagaccacag
    24781 tttattttta attaataata aaagatatag aaaacatgga ttgtttgagg caaaagatta
    24841 tattagtcaa gctcaatcat tagaaaatgc aggatatagt acagcagaag ataaaaaagg
    24901 aaatcgtata tatgcagagc tattaataga tgttattagg agttataatt tgcaattgat
    24961 agataataaa gttgagacaa aataattgtt aactttatat gaggagataa caagataaga
    25021 ttcttttcta caaaaagaat agaaaaattg taaaaaaaac taaaaaaatg tattgacttg
    25081 ttatttaaaa ggtgatatta ttattactgt actcgaaaga gaacaaaa
//
LOCUS       DAFAZV010000058        23745 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.058, whole genome shotgun sequence.
ACCESSION   DAFAZV010000058 DAFAZV010000000
VERSION     DAFAZV010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23745)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23745)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23745
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.058"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..468
                     /locus_tag="KOU88_003297"
     CDS             <1..468
                     /locus_tag="KOU88_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBK3213151.1"
                     /translation="WELYEKLVDGYFSMRKELNNPLLSASKELQAIFMLDKKQEVLET
                     KIENVNEKLENFMDDAPLFNIECESIVKEVKKVATKSLGGHGSKAYKNKSLRGKVYSD
                     IYHQIKREFGVDSYKAIKRCQLNKVLEIVNNYKLPIVFEEEIRLLNSQLSIVS"
     gene            570..1058
                     /locus_tag="KOU88_003298"
     CDS             570..1058
                     /locus_tag="KOU88_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213152.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAVGYDEKVSPTYAFNSSVENEIIKKERDITRLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKIMDMLYPRIKENELPLF
                     KN"
     gene            1805..1978
                     /locus_tag="KOU88_003299"
     CDS             1805..1978
                     /locus_tag="KOU88_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213153.1"
                     /translation="MATKSILKNVDVRKKAFGRNLVSALENAKNKQEKEVVLSKKCSE
                     VPKDKIKDIFGRF"
     gene            1978..2589
                     /locus_tag="KOU88_003300"
     CDS             1978..2589
                     /locus_tag="KOU88_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBK3213154.1"
                     /translation="MSGYLIVNLSNMLGELEEEEVKKILSSFSCPLNKDVEEFLKNKA
                     IEFSKQGLASTHLVLTSYKGKPVIVGYFTLANKYFTIKRKTLSNSLARKIVKFGQYNE
                     ELRRYIIGAPLIGQIGKNYSNNYNKLIKGDELLKIACDKIKAVQLDMGGKIVYLECED
                     KPKLIEFYKDNGFVDFGKRSLDKDETDSLDGDYLVQMLKYLKK"
     gene            2666..2854
                     /locus_tag="KOU88_003301"
     CDS             2666..2854
                     /locus_tag="KOU88_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213155.1"
                     /translation="MEIKKNTQDVVSERKNSLDSEFKIPASGVCYMAEFIKESREIIK
                     ELDKHFESCLDVLSKARL"
     gene            complement(2834..3151)
                     /locus_tag="KOU88_003302"
     CDS             complement(2834..3151)
                     /locus_tag="KOU88_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213156.1"
                     /translation="MSKNIDIRNLKQFQKKIERMEQNLKPDFDKIRTIILSKKFMNQH
                     TNFDSFDELLAFGNYIVNSEEDFLAIPDNEFDLFIVKNTDFPDWQTMLDSAYSKYLES
                     CLR"
     gene            3275..3502
                     /locus_tag="KOU88_003303"
     CDS             3275..3502
                     /locus_tag="KOU88_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213157.1"
                     /translation="MGFEISGNLNFDSVIDDLKKEVENNPTIFTSQNVGNKFKEKCKI
                     CEKISEFEILEDGKVKCLECGTEFELNLKVE"
     gene            3572..4264
                     /locus_tag="KOU88_003304"
     CDS             3572..4264
                     /locus_tag="KOU88_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213158.1"
                     /translation="MQDVKEKVKQDYLKGMKQKEISSKYDISLNTLKSWIKRYNWASE
                     KKKGAPINKRGAPFSNKNSVGHGAPKENKNAEKFGFFSKYLPEETQDLINEIKNKDKF
                     DILWEQITIQYAAIIRAQKIMYVKGKEEMVKELKKHESTENGEKIEYEFQFAWDRQAS
                     FLNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQKTRVEKLKCEVDNLSKDDIGDDEL
                     KISVDYGDRNDS"
     gene            4242..5495
                     /locus_tag="KOU88_003305"
     CDS             4242..5495
                     /locus_tag="KOU88_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBK3213159.1"
                     /translation="MVIEMIVRVNFNPDFKEANFTKKRYRAMKGSAGSGKSVNVAQDY
                     ILKLGDKKYQGANLLVVRKSEATHKYSTYAELTGAINRIYGKQADKYWKTTLNPLEIK
                     SKVTGNSIIFRGVNDAKQREKLKSINFSKGKLTWVWCEEATELMESDIDILDDRLRGI
                     LTNPNLYYQMTFTFNPVSSTHWIKRKYFDYKNDDIFTHHSTYLQNRFIDEAYYRRMQM
                     RKEQDPEGYKVYGLGEWGETGGAILKNYVIHEFPTEFEYFDNMRLSQDFGFNHANVVL
                     RIGFKDGELYICNEIYVHEMDTSEIIKIANSKGLEKNIFMYCDSAEPDRIKMWKSAGY
                     KAKGVKKGPGSVKAQIDYLKQLRIHVHPSCTNTIKEIQQWKWKQDERTGLYLDEPVEF
                     MDDAMAALRYSIDNKLKNNGISFLK"
     gene            5510..6952
                     /locus_tag="KOU88_003306"
     CDS             5510..6952
                     /locus_tag="KOU88_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213160.1"
                     /translation="MYISETDLIKVQLKKESTFNLVKVIEHYILKHRPEKYKQGEEYY
                     YGNADINNKRRYYLLDGAKVDDFTKVNNKAINNYHKLLVDQKVGYSVGNPIVFNADDD
                     NLTKLLNDLLGEEFDDTITELYLNASNKGVEWLHPYINRKGEFKYVIIPAEEAIPIWD
                     SKRQRELVAFIRFYYIEDIDGNKIKRVEYYTENDVTYFIERGNSFIQEFLYDEYGKMT
                     DIQEGHFRINNKEQGWGKVPFIPFKNNEKCVSDLTFYKSLIDIYDNNISTLADNLDEI
                     QEVIYVLKEYPGTSLQEFIDNIRYYKSIKVDGGGGVDKLEINIPVEAKKELLDRLEKN
                     IIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEYLKI
                     SGSKSYDYKTVQITFNHSMIINEAEKIDMAAKSTGIVSDETIVSNHPWVEDVNDELER
                     LKKQKEESIKEYEDAFPTKKKTEEGEPLDE"
     gene            6945..7985
                     /locus_tag="KOU88_003307"
     CDS             6945..7985
                     /locus_tag="KOU88_003307"
                     /inference="COORDINATES: protein motif:HMM:TIGR01641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBK3213161.1"
                     /translation="MNNIDYWIKTFNQLEEDVHNKGDTFNKELEKQYDIVLYNILREI
                     NNWYIKFAKDNKISMQEAEKLLNLRELAELKLSLEEYIKYGEENVISQKWMKELESAV
                     KRVRISRLKALELKIRHQVEVLYSKEYEDVNTLIADTYQDSYYHTAFETQKGIGIGLM
                     IAMLSMNNINKIVSSPWTTDGITFGNRIWNKHRPRLMSELNKGLKETLINGISPENLT
                     NKINKNFNTSKEEAKLLVKSELAFFSSLSQRDCFNSLGVEKYEIVSALDSKVCEKRCS
                     PLDGKVIEMKYYEIGVTAPPFHPRCRCVIVPYFDGEESYRAAREEDGGTYYVPSSIKY
                     KEWHKKYVKNTY"
     gene            8042..8284
                     /locus_tag="KOU88_003308"
     CDS             8042..8284
                     /locus_tag="KOU88_003308"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213162.1"
                     /translation="MLKLYILSIIVFCTGFYLYMLRLGNVKEVIEALKKYKAWKNYKL
                     IFIALFPLLNFIIGLIFIVVSLFATNKDIIESLEDE"
     gene            8285..8851
                     /locus_tag="KOU88_003309"
     CDS             8285..8851
                     /locus_tag="KOU88_003309"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213163.1"
                     /translation="MARFVKKAVEVEAFKFDIDIEPPIWIRKEIERGNAWVEHSIDKE
                     HTKMFIRTIEGLIYQVNIGDYIIQGVKGEIYPCKADIFEMTYEKVEYTATIENLTNYA
                     ENLEPGHKYIDKGSSKKNSLEFSVKLKLDTKDFDKNIENATKEIETFNEAVGRLEKKI
                     NRISAKENKVDIDKIVKQLEESLRERIE"
     gene            8870..9142
                     /locus_tag="KOU88_003310"
     CDS             8870..9142
                     /locus_tag="KOU88_003310"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213164.1"
                     /translation="MFKQKYIKKSNKISARNIIAFIITVIGITLGIFIGINIIMAHVL
                     GIANMVDNNTFTCVRLVYGLVGVISGYLIGKAIYLIASLISYIIYE"
     gene            9192..9422
                     /locus_tag="KOU88_003311"
     CDS             9192..9422
                     /locus_tag="KOU88_003311"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213165.1"
                     /translation="MKEYIIWFKSGNSISGIVDEDVADKLMQDFIEADSDCRNLKGYL
                     DEDGTTIIDLSQIEAISINNCSENNNIGFNPR"
     gene            9463..10026
                     /locus_tag="KOU88_003312"
     CDS             9463..10026
                     /locus_tag="KOU88_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBK3213166.1"
                     /translation="MDWLKELLEGIKIEDNKIDVASLQKSIEKKIKETTVTQEDYTNL
                     ETQLNTANETIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLNDAF
                     KSVKCRDEIALKAHLDMEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            10038..10937
                     /locus_tag="KOU88_003313"
     CDS             10038..10937
                     /locus_tag="KOU88_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBK3213167.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWESKTLTNQRKWSTLVHPADIDQTNYVASI
                     GNITQVYNEEQKFPEMDAYCISKIYADWIALGKTAETTALTTANILEVFDKLMEKMTE
                     ARVPAVGRILYVTPGVDTLIKNAKEIQRTVNIKDGGTSLNRQTTDIDSVKIVKVPSNL
                     MKTVYDFTTGWKAGAGAKQIFMSLIHPSAIITPVSYQFSTLDEPRAVTEGKYLYFEES
                     FEDVFILNKKADAIQFVVEGDGA"
     gene            10937..11167
                     /locus_tag="KOU88_003314"
                     /pseudo
     CDS             10937..11167
                     /locus_tag="KOU88_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11240..11641
                     /locus_tag="KOU88_003315"
     CDS             11240..11641
                     /locus_tag="KOU88_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213168.1"
                     /translation="MENNLIDDIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESLNFEAVEKSISEGDTKVDFAIGSG
                     SQTPEQRFDTLVNYLLTYGKNKILTFRCLRW"
     gene            11635..11982
                     /locus_tag="KOU88_003316"
     CDS             11635..11982
                     /locus_tag="KOU88_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213169.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDAITKRTNNKEVIVLENQ
                     PCKLSYKNITSATDGKVAKLEQTIKLFISPNIEIKAGSKLIINDKEYVRSGESAIYPN
                     HQEIILELLDDKA"
     gene            11982..12413
                     /locus_tag="KOU88_003317"
     CDS             11982..12413
                     /locus_tag="KOU88_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK3213170.1"
                     /translation="MARGGSVDFKELKKLQRKLQRLEDSQLDKFLKDCARELAARLVR
                     KARKPERTPKKTGTLKDGWGGIAYARKLPVTKVGDNYVIEVINPTPYASYVEFGHRTR
                     NHKGFVKGKYMMTISVMELREEADAIIEKKLMILLKKVFDA"
     gene            12406..12846
                     /locus_tag="KOU88_003318"
     CDS             12406..12846
                     /locus_tag="KOU88_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213171.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPINS
                     SKVLYPNARELKKNSFDVHYFPKSDNKAFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKSNNTEKMNDVELFGGLKRGDSIEN"
     gene            12830..13018
                     /locus_tag="KOU88_003319"
     CDS             12830..13018
                     /locus_tag="KOU88_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213172.1"
                     /translation="MVLKTNDLDKKSNDYKFTKEQIVNSKKYVNRKDLLNAILKDDEL
                     YSFSEVEDMINKFMKGVS"
     gene            13019..14329
                     /locus_tag="KOU88_003320"
     CDS             13019..14329
                     /locus_tag="KOU88_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBK3213173.1"
                     /translation="MALGGGTFVTQNKILPGAYINFISAKRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKIVVTTNIDDNTKFDVVTLLDNKKVDTQIAKVITDLEDNDYV
                     IWKKDATLEASAGLVFTGGTNGEAVTGAEYQAFLDKIESYSFNALGCLATTTEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKSDADYEGVVSVENKIKDTGLLESSLIYWTTGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKTGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNM
                     RAIEDFKADDVSVEPGSDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            14350..14826
                     /locus_tag="KOU88_003321"
     CDS             14350..14826
                     /locus_tag="KOU88_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBK3213174.1"
                     /translation="MSKNITMNVRDAISGSKAECFVTIKGKRYNFMQAINLEAKMEKN
                     KSEMPILGSITKGNKSTGSKFSGSATFYYNTSIFRELLYEYKETGEDIYFDMQITNED
                     PTSSVGRQTIILEDCNLDSGIIAKFDADGEYLDEDVDFTFENWRIVEKFNIANGME"
     gene            14879..15136
                     /locus_tag="KOU88_003322"
     CDS             14879..15136
                     /locus_tag="KOU88_003322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213175.1"
                     /translation="MIKIKDKYEIKDSISFDYSKKRTIEECVSEIYKKAGKYLIDIAD
                     KLALDTIEGSSLKPITIKIKLDEDGIATIEKETKYLIMEVE"
     gene            15138..15578
                     /locus_tag="KOU88_003323"
     CDS             15138..15578
                     /locus_tag="KOU88_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213176.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFVGEDGKPVEWELKAIDSD
                     RDRQLRKNSAIRVPVIGKKGKATGQYTSETDFNTYTLKLCVETIVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            15901..16059
                     /locus_tag="KOU88_003324"
     CDS             15901..16059
                     /locus_tag="KOU88_003324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213177.1"
                     /translation="MDNFLQNVLERLSVSLIVFLVSNLLKKRKKPLKAGTKSGWEFDL
                     KIRFHKFK"
     gene            complement(16768..16977)
                     /locus_tag="KOU88_003325"
     CDS             complement(16768..16977)
                     /locus_tag="KOU88_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213178.1"
                     /translation="MKEYEAELNISISIPFFTVISYLVIVSIVMLCLSALNNFANISS
                     VPVSALGSTTGFIIFNLIISLFKNK"
     gene            17244..17420
                     /locus_tag="KOU88_003326"
     CDS             17244..17420
                     /locus_tag="KOU88_003326"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213179.1"
                     /translation="MEILNLFWGFRLTIWNVNINRTGPSAAANPGFRLTIWNVNINVF
                     HTGIFFCNSFILTM"
     gene            17589..17765
                     /locus_tag="KOU88_003327"
     CDS             17589..17765
                     /locus_tag="KOU88_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006779947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBK3213180.1"
                     /translation="MPQKKMGRPTESVKDTMIRVRADKDTIDKLDECVNLLDSNRSEI
                     IRKGIDKIYDDLKK"
     gene            17891..18708
                     /locus_tag="KOU88_003328"
                     /pseudo
     CDS             17891..18708
                     /locus_tag="KOU88_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            18768..18926
                     /locus_tag="KOU88_003329"
     CDS             18768..18926
                     /locus_tag="KOU88_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213181.1"
                     /translation="MCESLLNEYNLKTDKDIEYFVKFVDVLYELKQISEEKFQEYAKV
                     LREILREQ"
     gene            19071..19589
                     /locus_tag="KOU88_003330"
     CDS             19071..19589
                     /locus_tag="KOU88_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK3213182.1"
                     /translation="MFCSNCGYEITGAGKFCSNCGTPTLADKVNNDDLFINVHGKELN
                     LTNIYKETKGDKILAIDIAMRLLGLDIKECKNIIYPAFKELSEKINIEEEKEILREDE
                     YKQTNVLEDDNVARCPRCGSVSLSAHKKGFGIGKAVVGASLTGGIGLVAGNLGAKKVR
                     VTCLNCGKQFWA"
     gene            19824..22178
                     /locus_tag="KOU88_003331"
     CDS             19824..22178
                     /locus_tag="KOU88_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBK3213183.1"
                     /translation="MAPALKNMNTSINATAKSLERLQQKLNNPINAGNIQASQQNLKN
                     IESILTRIEQKIGRNTNEQENFNNKIRKGSEEGSLLVSKLKSLAGVYIGIRGIESITK
                     AADTISSTKARLALMNDGLQTTEQLNKMIYLSAQSARASYADTAAQVAKLGILAGDAF
                     GSSAEVVKFTELMNKAFVIGGTSATEASAAMYQLTQAMGAGKLQGDEFRSIMENAPLL
                     AAKIADVMGKTKDQLKDLSSSGAITADVIRNALFKASDEIEKKFASMPITFSQALTMM
                     KNDAYMIFGQTLGKISGALQSVRFSEIVVSMRNVMIAISSNIYDTLNTIKNILNSDFF
                     SSFVSNVTLGAILIINGLGWVTNAALNVANVFAQNWSIIAPIIYGVIAAIAIYKGVLL
                     AGTIATTVASFVNSLYAVAAYKACAALAAQEFAIFGKISAQTMEALVTAQATAAQWGF
                     NAALLSCPIFWIIAGIIAFVVVVFVAVAAVNKFAGTSLTALGVIVGAVFAAVAFIQNI
                     MIWLFNRCVDVNEGITNGWNQCVYLMKQAIAKGVIFIIEKMASMNDSVNSAGNALGKA
                     FVDGANIAIRGVNKLIDLINKIPGINIGKVGEATFTPVKADNSYIKQQIDSLNKWVGN
                     APEKVKLERMGYKDIGAEFEKGNALGTKWQKSLEKKLKDTFDINKMLEDAKDKLGLKD
                     LWDKNNPLNNLGGFGGDLGKNVKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQEVINRF
                     TGVNIKIDMNNTNNISKDTDVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            22194..22889
                     /locus_tag="KOU88_003332"
     CDS             22194..22889
                     /locus_tag="KOU88_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK3213184.1"
                     /translation="MAYDFYLDGVQLPITPGKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFCRGQFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNMKVSLEEYNIVEDAENASDTKVAIKLKQYRDYSTKKLVPAPPKKTNETGRPSVKIE
                     PKRVDSVNAPNAKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKKVP
                     KYTIYKGQVLRLV"
     gene            22882..>23745
                     /locus_tag="KOU88_003333"
     CDS             22882..>23745
                     /locus_tag="KOU88_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBK3213185.1"
                     /translation="MSDELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGVGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYILYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQLFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     VLGDIRVRAGCL"
BASE COUNT         9656 a         2520 c         4487 g         7082 t
ORIGIN      
        1 tgggaattat atgagaagtt agttgatgga tatttctcta tgagaaaaga actaaataat
       61 cctcttttaa gtgcatcaaa ggagttacag gctatattta tgctagataa gaaacaagaa
      121 gtcttagaaa ctaaaataga gaatgttaat gagaagttag agaactttat ggatgatgca
      181 ccactattca atattgagtg tgaaagtatt gtaaaagaag ttaagaaggt agcaacaaaa
      241 tcactaggag gtcatggaag taaggcttat aaaaataaat ctttaagagg taaagtatac
      301 agtgatatat accatcagat taaacgagag tttggagtag atagttataa ggctataaag
      361 cgttgtcaat taaataaagt attagagatt gtaaacaatt ataagttacc tatagtgttt
      421 gaagaagaaa taagactttt aaatagtcaa ttatcaatag taagttaaat ttattcaaaa
      481 aaaggaaaag gagtgctccc acactccact tgtcaaaaat ctaaaacttt tatccaagat
      541 tattataaca taaacaggag tgtggaagta tggataataa tatcaataaa aaagaactat
      601 ttaaaaaagt agaaggtaga ctacatcatt ataaattttt aagtgcagaa attaaaaatc
      661 ttgaattaga tatagaaagt agagaaaatg agatatttgg gtgtaaggct gttggatatg
      721 atgaaaaagt aagtccaaca tatgctttta attcaagtgt ggagaatgag attataaaaa
      781 aagaaagaga tattactaga ttgaaaaaac tgaaaaaaga taaggaaatt gaaaagaaga
      841 aaatagaaaa tgcacttaca tgcttagata taagagaaga acattttttt aaactgtttt
      901 ataatagcag aatgaaaaat agtatggttt atatatcctt agaaatgaac tcagatagaa
      961 aaacatgtag atgtgtgagg gaaagattag tgtataaaat tatggatatg ctttatccaa
     1021 gaattaagga aaatgaacta ccattattta aaaattagaa aattccccag tttttcccca
     1081 gaaattccca ctttattccc cactttctcc cctttttgat taaaaaagca tgagataata
     1141 gtattgtgga aataaagatt tccctctcaa aacttaatat ttgactaggg ttaagggatt
     1201 gccctagtca ctatgaacag actaggcagg gcgtgaggac gctgttagtt caattctaac
     1261 tatgttcaaa atctattgat acactatatt aagtatttga attgagatta aaatctcata
     1321 cagttttgta tcttaattca gaggtctaaa aaccgagtgg ggcttggtaa cctcactcac
     1381 catgcaggta ctggtgttta atctaggttc gattcctaga acttgcgaca taatatatgt
     1441 atctccctac taaaaatgct aagtttactc caaacttagc attttacttt ttaaaaagaa
     1501 aaaagaaatt tttattgtca taatactatt tgtttaggta tattataatg tgcatactta
     1561 aaattaaata cttagcaagc atttgaatta atatacataa gatatatgac ataatttttt
     1621 atagtgtaag ttatttaaat taattataaa taacagtaat tttattatat aaaatgtaca
     1681 tattgtgaat aataataata aaatcatgta caaaatgcca actgataatt cctcgaaatg
     1741 tattgcatat ttaacgtaac gtcagtataa ttaaattata atagtgaagt ggaaggtggt
     1801 acttatggct acaaaaagta ttttaaaaaa tgtagatgta agaaaaaagg catttggaag
     1861 aaatctagta tcagctctag aaaatgctaa aaataaacaa gaaaaagaag ttgtattaag
     1921 taaaaaatgt tcagaagtac caaaagataa aataaaggat atattcggga gattttaatg
     1981 agtggctatt taattgtaaa cttaagtaat atgctaggag agctggagga agaagaagtt
     2041 aaaaaaattc tctccagttt ttcttgtccc cttaataaag atgtagaaga atttttaaaa
     2101 aacaaagcta ttgaattttc taaacaaggt ttggctagta cacatttagt gctaacttct
     2161 tataaaggca agcctgttat agttggatat ttcactctag ctaataagta ttttacaata
     2221 aaaagaaaaa cattatcaaa ctctttagct aggaaaatag tgaagtttgg acaatacaat
     2281 gaagaactaa gaagatatat tattggagca cctttgatag ggcaaatagg aaagaattat
     2341 tcaaataatt ataataaatt aatcaagggt gatgaacttc taaaaattgc atgtgacaag
     2401 ataaaagcag tacagttaga tatgggtggg aaaatagtgt accttgaatg tgaagataaa
     2461 cctaaattaa ttgaatttta taaggataat ggatttgtag actttggaaa aagaagcctt
     2521 gataaagacg aaacagattc gttagatggg gactatttag ttcaaatgtt gaaatatcta
     2581 aaaaaataaa agtacataaa atctaaaatg actatcttga tagatggtct ttttttatac
     2641 aataaattaa aaggagaatg aaattatgga gattaagaaa aacacacaag atgtagtatc
     2701 agaaagaaaa aattccctag attctgaatt caagatacct gcaagtggtg tgtgttatat
     2761 ggctgagttt ataaaggaat ctagggaaat cataaaagaa ttagataaac attttgaaag
     2821 ttgtctagat gttttatcta aggcaagact ctaaatattt tgaatatgct gaatcaagca
     2881 tggtttgcca atctgggaaa tcagtatttt taactataaa taaatcaaat tcattatcag
     2941 gaatagctaa aaagtcttct tctgaattga ctatgtaatt accaaatgca agtagttcat
     3001 caaaagaatc aaaattagtg tgttggttca taaatttctt gctaagaatt attgtgcgaa
     3061 tcttatcaaa gtcaggtttt aaattttgtt ccattctttc aattttcttt tgaaattgct
     3121 ttaaatttct aatgtcaata tttttactca taagaacacc tcctttcaat agaatattag
     3181 cataaaattg tggtgaattc tgctattgtc gaacgattgt tgaaggatat tgtataataa
     3241 catagaattt actatactat aaggaggtga ttatgtggga tttgagataa gtggtaattt
     3301 gaattttgac agtgttattg atgatttaaa aaaagaagtt gaaaataacc ctactatatt
     3361 tacatcacaa aatgttggaa ataagttcaa agaaaaatgt aaaatatgcg aaaaaatatc
     3421 tgaatttgaa atactagaag atggtaaagt taaatgttta gaatgtggga ctgaatttga
     3481 attgaatctt aaagtagagt aaacaaaaaa agaatctcaa ttatgaggtt ctttttttat
     3541 tcccaaaaca aacaaataaa gaggtggtga tgtgcaagat gtcaaagaaa aggtaaaaca
     3601 agattactta aaaggaatga aacaaaagga aatatcatca aagtatgaca ttagcttaaa
     3661 cactttaaag tcatggataa aaagatacaa ctgggctagt gaaaaaaaga agggtgcacc
     3721 tataaataaa agaggtgcac ccttttctaa taaaaattca gttggtcatg gtgctccaaa
     3781 agagaataag aacgctgaaa agtttggttt cttctcaaaa tacttacctg aagaaaccca
     3841 agacttaatt aatgaaataa agaataaaga taaatttgat attctttggg aacagataac
     3901 aattcaatat gcagcaataa taagagcaca gaagataatg tatgttaaag gcaaggaaga
     3961 aatggttaag gaattaaaga aacatgaaag cacagaaaat ggtgagaaga tagagtatga
     4021 atttcaattt gcatgggata ggcaagcatc ttttcttaat gcacagagta gagctatgag
     4081 tgaattaaga agtttaatta aacagtatga tgaaatgatt cataaggatt ggaatttggc
     4141 tacagaggag cagaaaacaa gagttgagaa gttgaaatgt gaagttgata acctaagtaa
     4201 agatgacatt ggagatgatg agttgaaaat aagtgtagat tatggtgata gaaatgatag
     4261 ttagagtaaa ttttaatcca gatttcaagg aagccaattt tactaaaaaa agatacagag
     4321 caatgaaagg ttcagcaggg agtggaaaat ctgttaatgt agcacaagac tatatactaa
     4381 agttaggaga taagaagtat caaggagcta atctattagt agttagaaag tcagaagcta
     4441 cacataagta ttcaacgtat gcagagctta caggagctat aaatcgtatt tatggtaaac
     4501 aagctgataa gtattggaaa actactttaa atcctttaga aattaagagt aaagttactg
     4561 gtaactctat aattttcaga ggagttaatg atgcaaaaca aagagaaaaa ttaaaatcaa
     4621 ttaacttctc gaaaggaaaa ttaacatggg tttggtgtga agaagctaca gaacttatgg
     4681 aaagtgacat agatatacta gacgaccgtt taagaggtat tttaactaat cctaacctat
     4741 actatcaaat gacatttaca tttaatccag tctcatctac tcattggata aaaagaaagt
     4801 attttgacta taaaaatgat gatatattta ctcatcatag tacttatcta caaaatagat
     4861 tcatagatga ggcttactac agaagaatgc aaatgagaaa agagcaagac cccgaagggt
     4921 acaaagtcta tggtcttgga gaatggggag aaactggtgg agcaatactt aaaaactatg
     4981 ttatacatga atttcctacg gaatttgaat actttgataa tatgagactg tcacaagact
     5041 ttggctttaa tcatgcaaat gtagtactca gaattggttt taaggatgga gagttatata
     5101 tatgtaatga aatatatgta catgaaatgg atacatctga aataataaag attgcaaaca
     5161 gtaaaggttt agaaaagaat atatttatgt actgtgatag tgctgaacca gatagaatta
     5221 agatgtggaa gagtgcagga tataaagcta aaggagttaa aaaaggacca ggaagtgtta
     5281 aagctcaaat agattatttg aaacaattaa gaatacatgt acatcctagt tgcactaata
     5341 ccataaaaga aatacaacaa tggaaatgga aacaagatga aagaactgga ttatatcttg
     5401 atgaaccagt tgagtttatg gatgatgcaa tggctgctct tagatattct atagataata
     5461 agcttaaaaa taatggaata agcttcttaa agtaaaggag gcgttaaata tttatataag
     5521 tgaaacagat ttaataaaag ttcagttaaa aaaagagagc acatttaacc tagtaaaagt
     5581 tatagagcat tatattttaa aacatagacc agagaaatat aaacaaggtg aagaatacta
     5641 ttatggcaat gcagatataa acaataagag aagatattat ctcttagatg gagctaaggt
     5701 tgatgatttt actaaagtta ataataaagc aattaacaac taccataagc ttttagttga
     5761 ccaaaaggta ggctatagtg tcggaaatcc catagtattt aatgcagatg atgataatct
     5821 cactaagctt ttaaatgact tactaggaga agagtttgac gatacaataa cagaactata
     5881 tctcaatgct agtaataaag gggttgaatg gttacatcca tatattaata gaaaaggtga
     5941 gtttaaatat gtaataattc cagctgaaga agcaattcct atttgggata gtaaaagaca
     6001 gagggaatta gttgcattta ttaggtttta ttatattgaa gatatagatg gaaataaaat
     6061 aaaaagagtt gagtactaca cagaaaatga cgtaacttac tttattgaaa gaggtaatag
     6121 ttttattcaa gaatttttat atgatgaata tggaaaaatg actgatatac aagaaggtca
     6181 ttttagaata aataacaaag aacagggatg gggtaaagtt ccatttatac cttttaaaaa
     6241 taatgaaaag tgtgtctcag atttaacttt ctataaatca ttaatagata tatatgacaa
     6301 taatatttct acactagcag ataacttaga tgaaatacaa gaggttattt atgtattaaa
     6361 agaatatcca ggaacaagtc tacaagagtt tatagataat ataagatact ataaatcaat
     6421 taaagtagat ggtggaggtg gagttgataa actagagata aatataccag ttgaagctaa
     6481 aaaggagctt cttgatagat tggaaaagaa tataattatc tttggtcaag gagttaatcc
     6541 agaatctcaa aacacaggtg acaaatcggg cgtagcactt aaatttttat attcactact
     6601 tgacttaaaa tgttctaaga ctgaaaagaa gtttaaaaaa gcaattagag agcttttatg
     6661 gtttgtgtgt gagtatttaa agataagtgg tagtaagagc tatgattata aaacagttca
     6721 aattactttt aatcactcta tgataataaa tgaagctgaa aagatagata tggcagctaa
     6781 atcaactgga attgtatcag atgaaactat tgtttctaac catccttggg tcgaggatgt
     6841 taatgacgaa cttgagagac ttaaaaagca gaaagaagaa agtataaaag aatatgaaga
     6901 tgcttttcca actaaaaaga aaactgaaga aggtgaacct ttagatgaat aatatagatt
     6961 actggataaa gacatttaat cagttagaag aagatgttca taataaaggt gataccttta
     7021 acaaagaatt agaaaagcaa tatgatatag tactttataa tattcttagg gaaataaata
     7081 attggtatat aaaatttgct aaggataata aaataagtat gcaagaagct gaaaagttat
     7141 taaatctaag agaattagct gaacttaaat tatcattaga agaatatatc aagtatggag
     7201 aagaaaatgt aattagtcaa aagtggatga aagaactaga aagtgcagtt aaaagagttc
     7261 gtataagcag actaaaagca ttagagttaa aaataaggca tcaagttgag gtattatact
     7321 caaaagagta tgaggatgta aatacgctta tagcagacac ttatcaagat agctattatc
     7381 atactgcatt tgaaactcaa aaaggtattg gaattggatt aatgatagcc atgcttagca
     7441 tgaataatat taacaaaata gttagtagtc cttggaccac tgatggaata acatttggta
     7501 atagaatttg gaataagcat agaccaaggt taatgagtga acttaacaaa ggattaaaag
     7561 aaacattaat taatgggata tctcctgaaa acttaacgaa taaaattaat aaaaatttta
     7621 atacaagcaa agaagaagct aagttattag taaaatctga gcttgccttt tttagttcat
     7681 taagtcaaag ggattgtttt aatagtctag gtgttgagaa atatgaaata gtaagtgcat
     7741 tagatagtaa ggtttgtgag aaaagatgta gtcctcttga tggtaaagta attgaaatga
     7801 aatactatga gataggagtt actgctccac catttcatcc tagatgtagg tgtgtaatag
     7861 taccatattt tgatggtgaa gaaagttata gagctgcaag agaagaagat ggtggaactt
     7921 attatgtacc atctagtatt aagtataaag aatggcataa gaagtatgtt aaaaacactt
     7981 actaagttag taggtgtctt tattatgtaa aaaataaaat ttattgagag ggtgatttga
     8041 aatgcttaaa ttatatattt tatcaataat tgtattttgc acagggtttt atttgtatat
     8101 gttaaggctt ggaaatgtta aagaagtaat cgaagcttta aaaaaatata aggcttggaa
     8161 aaactataaa cttattttta tagctttgtt tccattgtta aactttatta ttggtttaat
     8221 atttatagta gtttctttat ttgcaacgaa caaggatata atagaaagtt tggaggatga
     8281 ataaatggct agatttgtaa agaaagcagt tgaagtggaa gcttttaaat ttgatataga
     8341 tatagaacca ccaatatgga tacgaaaaga gattgaacgt ggcaatgctt gggttgaaca
     8401 ctctattgat aaggaacata ctaaaatgtt cataagaact attgaagggc taatatatca
     8461 agttaacata ggggattaca ttatacaagg agtaaaagga gaaatatatc cttgcaaagc
     8521 tgatatattt gaaatgactt atgagaaagt tgaatatact gcaactattg aaaatttaac
     8581 aaactatgct gaaaatttag aaccagggca taaatatatt gacaaaggaa gtagcaagaa
     8641 aaatagctta gaattttcag ttaaattaaa actagataca aaagactttg ataaaaatat
     8701 agaaaatgct acaaaagaaa ttgaaacatt taatgaagca gtaggcagac tagagaaaaa
     8761 aataaatagg atatctgcaa aagaaaataa agttgatata gataagattg taaaacaatt
     8821 agaagaaagt ctaagagaac gtattgaata agttttgggg gatggaaata tgtttaaaca
     8881 gaaatatatt aagaagtcaa ataaaataag tgctagaaat attatagcat ttattattac
     8941 agttattggt ataactttag gtatttttat aggtatcaac ataatcatgg ctcatgtttt
     9001 aggaatagct aacatggtag ataataatac ttttacctgt gttagattag tttatggctt
     9061 agtaggagtt ataagtggat atttaatagg aaaagcaata taccttatag cttcactaat
     9121 aagctatatt atttatgaat aatttgttca aagatttttt atcatgtaaa aacaaaagga
     9181 ggcttatttt attgaaagag tatataattt ggtttaaaag tggcaatagc atatctggaa
     9241 tagtagatga agatgttgct gataagttaa tgcaagattt tattgaagct gactcagatt
     9301 gtaggaactt gaaaggatat ttagatgaag atggaacaac aataatagat ttatcacaaa
     9361 tagaagctat atcaataaat aattgtagcg agaataataa cattggtttt aatcctagat
     9421 aaggcttttt tattatgtaa aaaatgaaag gagacattta aaatggattg gttaaaagaa
     9481 ttattggaag gaataaaaat agaggataac aagattgatg tagcgtctct tcaaaaatct
     9541 atagaaaaga aaataaaaga gactacagtt actcaagaag attatacaaa tcttgaaaca
     9601 cagcttaata cagctaatga aactattaaa aagtttgaag gaggtatgac aaaagaagat
     9661 gtagagaatc taaaaacaac ttatgaaact gataagaaaa ctttggaaga aacctacaaa
     9721 aaagaaattg aagaaaagga ctttaattac tggttaaatg atgcttttaa gtctgttaaa
     9781 tgtagggatg aaatagcatt aaaagctcat ttagacatgg aagcactaag aaatagtaaa
     9841 gatagacaaa aagcttttga agagcaaata aaccctttga aacaggataa agattatttg
     9901 tttaatgcaa cactagaagg tgaagaacct aaaatagata ctataacacc aggacaagag
     9961 cctaagataa atgattttgg ttttaatttt actggggtaa gacctcatga aaataataat
    10021 aaataggagg aaataaaatg gcagcactaa attatgcaaa agaatattca aatgttttag
    10081 cacaagcata tccttatact ttaaacttcg gggatttgta tgcaacacca aataatggaa
    10141 gatatagatg gactggttct aaaacaatag aaataccaac tatatctaca actggaaggg
    10201 tagattcaaa cagagataca atagcagtag ctcaaagaaa ctatgataat gcttgggaat
    10261 ctaaaacatt aactaaccaa agaaaatggt ctacattggt tcatccagca gatattgacc
    10321 aaactaacta tgtagcatca ataggaaata taactcaagt atacaatgag gaacaaaaat
    10381 ttcctgagat ggatgcttac tgtatatcta aaatatatgc tgattggata gctctaggta
    10441 aaacagcaga gacaactgct cttacaacag caaatatctt agaggttttt gataagttaa
    10501 tggaaaaaat gacagaagct agagtacctg ctgttggaag aatattatat gttacaccag
    10561 gagttgacac tttaatcaag aatgcaaaag agatacaaag aactgtaaat ataaaagatg
    10621 gaggaacttc tcttaatcgt caaacaactg atattgattc agttaagata gttaaagtgc
    10681 catctaatct tatgaaaaca gtatatgact ttactactgg atggaaagca ggtgcaggag
    10741 ctaagcaaat atttatgtct ttaatacatc caagtgcaat aattacacca gtttcttatc
    10801 aattttctac attagatgaa ccaagagcag ttacagaagg aaaatattta tactttgaag
    10861 aaagttttga agatgtattt atattaaata aaaaagctga tgcaatacaa tttgttgttg
    10921 aaggagatgg agcataatgg cacaagtaag gaaattaaat agaatattaa ctatagaaga
    10981 atgtaaaata gatgatttct tagaaatggg atatgattta atagataaag ctggaaaagt
    11041 agagaaatat ggtaagtctt taaatgtaaa ggatttggtt gctgaaaata atattttaag
    11101 aaacaaagta gaatctttag aagtagaaaa taagcagctt aaagagaaag taaaaacttt
    11161 agaggaagaa gatatccaat ctatagaaaa agcagagcct acagaaaaga ataagtctaa
    11221 caaaaagtag gtgaaaatta tggaaaataa tctgattgat gatatagaaa aaagacttga
    11281 aagttttgga tatatattaa aagatgggga taagtggtta ataggttttg taagagaaaa
    11341 gatagaaaat attattaagc tggattgtaa tataaaaact atgccaattg aactgaaaga
    11401 aattgaagtt gatatgatag ttggagagtt cttatttact aaaaaaaata tgggtcaatt
    11461 agatatagaa agtcttaatt ttgaagctgt agaaaagtct atatcagaag gtgatacaaa
    11521 ggtggatttt gctataggaa gtggctctca aacaccagaa caacgctttg acactcttgt
    11581 aaactatctt ttaacttatg gtaagaataa gatattaact tttaggtgtt taagatggta
    11641 agtaaaacta gaaaagcaat agaaatgtta tatagagata aatgcactat agtagaatat
    11701 caaccaatca aagacgctat tacaaaacga actaacaata aagaagtaat tgtattagag
    11761 aatcaaccat gtaagctttc atataaaaat attacatcag ctacagatgg aaaagtagct
    11821 aagctagagc aaactattaa actctttata tctccaaata tagaaattaa agcaggttca
    11881 aaacttatta taaatgataa agagtatgta agaagtggag aatcagctat atatcctaat
    11941 catcaagaga taatattaga attactggat gataaagcgt aatggctaga ggtggaagtg
    12001 ttgattttaa agaattgaag aagctacaaa gaaaattgca aaggctagaa gatagtcagc
    12061 ttgataaatt tttaaaagat tgtgcaagag aattagctgc aagacttgtt cgtaaagcta
    12121 ggaagcctga acgtacacca aaaaagactg gaactctaaa agatggttgg ggtgggatag
    12181 cttatgctag gaaacttcct gttactaaag ttggagataa ttatgttata gaagttatta
    12241 acccaactcc ctatgcaagt tatgtagagt ttggtcacag aactagaaat cacaaaggct
    12301 ttgttaaagg aaaatatatg atgactattt cagtaatgga attaagagaa gaagcagatg
    12361 caataataga gaaaaaatta atgattttat taaagaaggt atttgatgct taataatata
    12421 attgatggaa tatcagtaaa attagataaa tcgtttggag aaaaatatac aatttacagt
    12481 gaagatgtgg aacaaggtat aaatgaacct tgttttttta ttgttcctat aaattcgagt
    12541 aaagtattat atccaaatgc tagagagtta aagaaaaatt cttttgatgt acactatttt
    12601 cctaaaagtg ataataaggc atttgaaata aatgagatag ctgaaatgtt attggaggaa
    12661 ttagagtata tagaaattga tggagattta gtcagaggta caaatatgaa ctttgaaatt
    12721 atagataatg ttcttcattt cttcgttgat tataattact ttactataaa aagtaataat
    12781 acagaaaaaa tgaatgatgt tgaattattt ggtgggttaa agagaggtga tagtattgaa
    12841 aactaatgat ttagataaaa aatctaatga ctataagttt actaaagagc agatagttaa
    12901 ttctaagaag tatgtaaata gaaaagactt gttaaatgca attttaaaag atgatgaatt
    12961 gtattccttc tcagaggtag aggatatgat aaataaattt atgaaaggag tgagttagat
    13021 ggctttaggt ggaggaacat ttgtaacaca gaataaaata cttccaggtg cttatataaa
    13081 ttttatctca gctaagaggg caactagttc attatctgat agaggtattg tagcaatgcc
    13141 acttgaactt gattggggta ttgatgaaga agtatttcaa gtaactagtg atgattttga
    13201 gaagtattca gtaaagtatt ttggatatga ttatacacat gaaaagttaa aaggtttgag
    13261 agacttattt aaaaatataa gactaggata tttctataaa ttaaataaag gtgttaaagc
    13321 tagttgcact attgctactg ctaaatatag tggaataaga ggtaatgatt tgaagatagt
    13381 agttacaaca aacattgatg ataacactaa gtttgatgtt gtaacacttt tggataataa
    13441 gaaggtagat actcaaatag caaaagttat tacagattta gaagataatg attatgtcat
    13501 ttggaaaaag gatgcaacat tagaagcaag tgcaggactt gtatttactg gtggaactaa
    13561 tggcgaagct gtgacaggag cagagtacca agctttctta gataaaatag aaagttattc
    13621 atttaatgca ctagggtgtt tggctacaac aacagagatt aaaagtttgt ttgtagaatt
    13681 tacaaagaga atgagagaca aagtaggagc aaagtttcaa actgtattat ataagaaaag
    13741 tgatgcagat tatgagggtg tagtatctgt agaaaataag attaaagata ctgggttatt
    13801 agaatctagc ttaatttact ggactactgg agctatagct ggatgtgata taaataaatc
    13861 taatactaat aaaaaatatg atggtgagtt tgatgttgat gttaattata ctcaaataca
    13921 acttgaagaa gctttaaaaa ctggtaaatt tatattccac aaggtgggag atgaagttca
    13981 tgtgttagag gacataaata cttttgtatc atttacagat gataaaaatg acgatttttc
    14041 aagtaaccaa agtgttagag tacttgacca gattgctaat gatatagcga ctttatttaa
    14101 tacaaagtac ttgggtgaag taccaaatga taaatctggt cgtatctcgt tttggaatga
    14161 tgtagttaag catcatgaac aactgcaaaa tatgagagca atagaagatt tcaaagctga
    14221 tgatgtttct gtagaacctg gaagcgataa gaagactgtt gtagtaagtg atgctgtaaa
    14281 agttattagt gctatgagta agctttatat gactgtttca gttagttaag agaggagtgt
    14341 gataaataga tgtctaaaaa tattactatg aatgttagag atgcaataag tggttctaaa
    14401 gctgaatgtt ttgtaacaat aaaaggtaaa agatataatt ttatgcaagc tattaattta
    14461 gaagcaaaaa tggaaaagaa taaaagtgag atgccgattt taggcagcat tacaaaagga
    14521 aacaaaagta caggaagtaa attttcaggg agtgcaacat tttattataa tacttctatt
    14581 tttagagagt tgttatatga atataaagaa acaggcgagg acatttactt tgatatgcaa
    14641 attaccaatg aagaccctac atcaagtgtc ggaagacaaa ctataatact tgaagattgc
    14701 aacctggata gtggaataat tgctaagttt gatgctgatg gcgagtattt ggatgaggat
    14761 gtagatttta cttttgagaa ttggagaata gttgagaagt tcaatatagc aaatggtatg
    14821 gaataagata cacatttata aattatagat gtgtattttt tatttacaaa attaggagat
    14881 gattaaaatt aaagataaat atgagataaa agattcaatt tcttttgatt atagtaaaaa
    14941 aagaactata gaagaatgtg ttagtgaaat atataaaaaa gcagggaaat atcttataga
    15001 tattgctgat aaactggcac ttgatacaat tgaaggttca tcattaaaac caattacaat
    15061 aaaaatcaaa ctagatgagg atggcattgc aacaatagaa aaagaaacaa aatatttaat
    15121 catggaggta gaataatatg ggagatttaa acgctttttt aagtcaaaat gcaataaaag
    15181 tagagaatag aaagtatgtg gcaagtgaaa ggtttgtagg tgaagatgga aaaccagtag
    15241 aatgggaact taaagcaata gattcagata gagatagaca gttaagaaaa aattctgcta
    15301 tcagagttcc tgttataggc aaaaaaggaa aagcaacagg gcaatacact agtgaaacag
    15361 attttaatac ttacactttg aaattatgtg tggaaactat agtatttcca gatttacatg
    15421 atgcagaact tcaaaatagc tatggtgtaa tgggagcaga ggaactatta acaacaatgt
    15481 taactcctgg cgaatacaca gacctttcaa gtgaagtagg agaggtaaat ggttttgata
    15541 gaacttttga agataaagta gaagaagcaa aaaactaatt gaaggaggcg attatgatgc
    15601 tagtgtagct cattattgcc ttcataaatt caaatggaaa ccacatgaat atacagattt
    15661 accagactac gagagggcat ttgttgctgc ttctatagat attaaagtag aagaagaaat
    15721 aaaagaagaa aaaaagactg ctaaagaagc tagaagaagt agaagaagat aaaatatagg
    15781 taaaatatgt aagaattata tgttataata tttttagcaa gaagatgtaa tctacaattt
    15841 atagagtgaa gttcatacaa aagattatcc tcccaacgta tagaagggag gtgaatatgt
    15901 atggataatt ttttacaaaa tgtactagaa agactatctg ttagtttaat agtttttcta
    15961 gttagcaatt tacttaaaaa acgtaaaaaa ccactcaaag ctggcactaa gagtggttgg
    16021 gaatttgatt taaaaatcag attccataag ttcaaataag tattatgaac ttcactctac
    16081 tgcaaataga ttgtagttct tcttgttttt attataccac aaaaaattat aaataaaacc
    16141 gttgtttata taaaatattt gaaatgatag cacattcccg ttttgggaac atggtcaaaa
    16201 ctcaaactat attactggta ttatattaaa tatttagcat caaaattaaa taaagcactt
    16261 actttttggt aggtgctttt ttatattcaa atctgtgtac ttaattgaaa tatttggtaa
    16321 aatatgtaag aattatatga tataataatt gtagcaagga aaataaaatt gaaaagctaa
    16381 gggtgatttt ctcatataaa cgccaaattc caatatagga aggaggtgaa tttatatgtt
    16441 aattaacttt ttattgagta tagtagctgg aattgtttca gcttacattt acgagaaaat
    16501 aaaaaatcac ccaaacgcca ataagggtga tttaaagaaa taacttttaa attctaatca
    16561 attagagaaa ttcacctttt acaaagtaaa ttttatctcc ttgctattat tataccacaa
    16621 attggtacag atattcaaaa ataatatttt tatgatatgg taaaaatata gaagtattgt
    16681 ggtatttcag cttcgagtaa attgtctaaa atgttataga cggttttata ttaactatat
    16741 agtatgtaaa tattaaaata ttttcattta cttattctta aataaactaa taataagatt
    16801 aaatataata aatccagttg ttgaacctaa agcactaaca ggtactgatg atatattagc
    16861 gaaattattc aatgctgata gacataacat tactatagaa actataacta aataagatat
    16921 cactgtaaaa aatggaattg aaatacttat atttaactct gcttcatatt ctttcataat
    16981 atcattcctt tcaaattatt ttacttaact ttattatagc atttaaacat aattaaatgt
    17041 aaaaatacag ttaaaaatta attgaaaata tcaattatat gttgtgatat aataaaatta
    17101 tagaagtttt gcagtgagcg atatttgtga taaaatatgg cctaacactt gaaatataat
    17161 gtattgagga cgtatgataa gtattatcat ttgcactact catggttcac tgcaaatttg
    17221 agagaggtgt gtatgtgtaa gtcttggaaa tactcaattt attttggggt tttagattaa
    17281 ctatatggaa tgtaaatatt aatagaactg gtccgagtgc tgctgctaat cctggtttta
    17341 gattaactat atggaatgta aatataaatg tatttcatac aggaatattt ttctgcaaca
    17401 gttttatatt aacaatgtag ataaaaatta aataaagaaa agaaagcact tacaaacatg
    17461 taggtgcttt tgttttgctc aaattggtcg gttgagtaaa ataattagga aaaattggta
    17521 taagtaattg acttttgttg ccacataaat tataatatat ttgtagcaac gaaagtgagg
    17581 tgaaataaat gccacaaaaa aagatgggtc gtccaacaga aagtgtaaaa gatactatga
    17641 ttagagtaag agctgacaaa gatactattg ataagttaga tgaatgtgtg aatttattag
    17701 atagtaatcg ttctgaaata ataagaaaag gtatagacaa aatatatgat gacctaaaaa
    17761 aataacaaaa atagagtgtt cgcccgacca agtttgaaca ctctatttaa acaccagaag
    17821 ttaccttcta tgaaatatat tctatcatag taaggtactt cttacaatca aatttaagga
    17881 ggaatttact atgaatgaat taatgaattt tgaaggaaaa gagattgaaa tatttgaata
    17941 taatgggcaa gttttattta atccatatga ttgtggaaga tgtttagagc taagtgatag
    18001 tgcaataaga aatcacttat ctaaaatgaa tgatacccaa gctatattat taaaaaattc
    18061 agctgtccta gataaggaca tccgaaaact gaataatgca ggtgaaaagt tcttaacaga
    18121 gagtggagta tacaagttaa tatttaaatc tcagaaagaa gaagcagaga agtttcaaga
    18181 ttggataagc gatgaagtac ttccagccat tcgacaaact ggtgcataca taactaacaa
    18241 tgctgaccca gataagttga gagaaaaagc aagcgaaatt gaaaagttac aactggctta
    18301 taatagtaca tctatgttga aagaactatt agatgatgca ggctttgaca ataaatctaa
    18361 attactaaca gcaaagacat tgtacaaaaa gcgggcattg atttaccaat agagatagat
    18421 gaagaagagc attattttga cacaaaacaa atagcgtcta aattgaaaat atattctaaa
    18481 agtaataaac cagctcagat ggctgtttgt gagattatta aaaagataaa attagaagaa
    18541 aatgaagtaa aaggagtttg ggaaacaaat ggctcttgga ctgggactgt aaataagtat
    18601 acagaaagtg taatagagaa gattaagtgt tggatagatg aaaataacaa gcctacaaag
    18661 atacaaggtg aaaagaagaa ttatcatgta gtttataaga ttgagtaaat tctattgtat
    18721 taaataattt agtttagttt actttagttt tgagggggat taatacaatg tgtgaaagtt
    18781 tacttaatga atataattta aaaactgata aggatataga gtattttgta aaatttgttg
    18841 atgtgttata tgaattaaaa cagattagtg aagaaaagtt tcaagaatat gcaaaggtat
    18901 taagagaaat tcttagggag caataagaaa atgaaaatat tttagataat atattaaaaa
    18961 cacttactca ggtaggtgtt tttttattga aaggaggtga ttataatgta aaaattttac
    19021 gtatatagta taataatgct ataaaataaa tattatgtga ggtgattgtt gtgttttgtt
    19081 caaactgtgg ttatgagata actggtgcag gcaaattttg ctcaaattgt ggaacaccta
    19141 cattagcaga taaagttaac aatgatgatt tatttataaa tgttcatgga aaagaattaa
    19201 atctgactaa tatttataaa gaaactaaag gagataaaat cttagcaatt gatattgcaa
    19261 tgaggttact aggactggac ataaaagagt gtaaaaatat tatatatcca gcttttaaag
    19321 aattaagtga aaaaataaat atcgaagagg aaaaagagat attgagggaa gatgagtata
    19381 aacaaactaa tgtacttgaa gatgataatg ttgctcgttg ccctaggtgt ggttctgttt
    19441 cattgtctgc acataagaag ggttttggta taggaaaagc agtagtagga gcgagtctaa
    19501 ctggtggaat aggtttagta gctggaaatt taggagcaaa gaaagttaga gttacttgtt
    19561 taaattgtgg taaacaattt tgggcataaa taataaacac ttactaatgt aggtgttttt
    19621 tatatgaaaa tttatgaaag gagagtgagg aaatggcaac aatacaaact tcaataaaga
    19681 tttttgacgg aatgacacct gcatttagaa acatgactac ttctattaac acaacgatta
    19741 acagtttaga gagattacaa cgagaattga gaaatcctct ggatgaaggt ggaatacaag
    19801 catctgtaaa aatttttgat agaatggcac ctgcacttaa aaacatgaat acatctatta
    19861 atgcaacagc taaaagttta gagagattac aacaaaaatt gaacaatcct ataaatgcag
    19921 gtaatataca agcttcacag caaaacttaa aaaatattga aagtatttta acgaggatag
    19981 aacagaaaat tggaagaaat acaaatgaac aagaaaactt taataataaa ataagaaaag
    20041 gaagtgaaga aggttctcta ttagtatcta aacttaaaag cttggcgggt gtatatattg
    20101 gaataagagg gatagaaagt attacaaagg cagctgatac aatctcaagt acaaaagcaa
    20161 gattggcttt aatgaatgac ggattacaga caacagaaca attaaacaag atgatttatt
    20221 tatctgctca aagcgctagg gcaagttatg cagatacagc agcacaagtc gctaagcttg
    20281 gaatattagc aggagatgcg tttgggagtt cagccgaagt agtgaagttt acagaactta
    20341 tgaataaagc ttttgtaatc ggtggaacat cagcaactga agctagtgcg gctatgtatc
    20401 agcttactca agctatgggg gcaggaaaac ttcaaggtga tgagtttcgt tccataatgg
    20461 aaaatgcacc attactagct gctaaaatag ctgatgtaat gggaaaaact aaagatcaat
    20521 taaaagattt atcaagtagt ggagcaataa cagcagatgt tataagaaat gcgctgttta
    20581 aagcttctga tgagatagaa aagaaatttg caagtatgcc aatcactttt tctcaagcac
    20641 tcacaatgat gaaaaatgac gcctatatga tatttggtca gacattagga aaaataagtg
    20701 gagctttgca aagcgttaga tttagtgaga ttgttgtatc tatgcggaat gttatgattg
    20761 caatatcttc aaatatttat gatacattaa ataccataaa aaatatatta aatagtgatt
    20821 tcttctcaag ttttgttagc aatgttacat taggagcgat actaattatc aatggactgg
    20881 gatgggttac taatgcagca ctaaatgttg ctaatgtctt tgctcaaaat tggtcgatta
    20941 ttgctcctat tatttatggg gtgatagcag caattgcgat atataaagga gtattacttg
    21001 caggtacaat tgccactacg gtagcatctt ttgtaaattc attgtatgca gtagcagcgt
    21061 ataaagcttg tgcagcttta gcagcacaag aatttgcgat atttgggaaa atatctgcac
    21121 aaacgatgga agctttggta acagcacaag caacagcagc acaatggggt tttaatgcag
    21181 cattattatc ctgtccaatt ttttggataa tagcaggtat tatagcattt gtagtagtag
    21241 tttttgttgc agtagcagca gtaaacaaat tcgcaggaac gagtttaact gccttaggag
    21301 taatcgtagg tgcagtattt gcagcagtag catttataca aaatataatg atatggctat
    21361 ttaatagatg tgtagatgta aatgaaggaa ttacgaatgg atggaatcaa tgtgtatatc
    21421 taatgaaaca agctattgca aaaggtgtaa tctttataat tgaaaaaatg gcatctatga
    21481 atgactctgt gaatagtgca gggaatgcac ttgggaaggc ttttgtggat ggggcaaata
    21541 tagcaataag aggggtaaac aaattaattg acctaataaa taaaatacca gggataaata
    21601 ttggtaaagt aggagaggca acgtttacgc cagttaaggc agataatagt tacatcaagc
    21661 aacagattga cagcttaaat aaatgggtag gaaatgcacc agaaaaagtt aaattggagc
    21721 gaatgggata caaagatatt ggagcagaat ttgagaaagg aaatgctcta ggaactaagt
    21781 ggcaaaaatc tctagaaaag aaattaaaag atacttttga cattaataag atgctagaag
    21841 atgcaaaaga caagctagga ttaaaagatt tgtgggataa aaacaatcca cttaataatc
    21901 ttggaggatt tggtggagat ttaggaaaaa atgtaaagga cacggcagga aacactgcaa
    21961 aaatggctaa aacaatggat aaaagtcaag aagatttaaa atatcttaga gatattgcag
    22021 agcaggaggt aataaaccga ttcacaggag taaacattaa aattgacatg aacaatacaa
    22081 acaacataag taaagataca gatgtggatg gaatagtaaa tgtcttaaca gaaaaactga
    22141 atgatgctat ggttgtatca gcagaaggaa tagtttagaa aggagggata taaatggctt
    22201 atgattttta cttggatgga gtgcaattac caatcacacc tggcaaatta gagattaaag
    22261 taacaaacaa aaataaaaca gttgatttaa taaacactgg agaagtaaac atactaaaaa
    22321 aagaagggct atctgaaata agttttgaag cagagtttac acataataaa ttgccttttt
    22381 gtagaggtca atttagagat gttcaattct ttttaagtaa actggaatta ctaaagacag
    22441 attgtaagcc atttcaattt attgtttcaa gggaattagg taataaagta ctatttaaca
    22501 ctaatatgaa agtgtcatta gaagaatata acatagtaga agatgcagag aatgcctcag
    22561 atacaaaagt tgcaataaag ttaaaacaat atagagatta ctcaactaaa aagttagttc
    22621 ctgctccacc taaaaaaact aatgagactg gtagaccaag cgtaaagata gagccaaaac
    22681 gagttgattc agtcaatgca ccaaatgcta aaacatacac agtcaaggca ggggatagtc
    22741 tttggtcaat ttgccaaaaa cagttaggta atggctcact gtataagaag gtatatgagt
    22801 taaataaatc aatgatggat aaggctaaca agggcaaaaa agtacctaaa tataccatct
    22861 ataaagggca ggtgttgagg cttgtctgat gaattagttt tggcaaatga tagggatgta
    22921 agattagtca tagcacattg ggaagatttc tacgaacctg tagttttgga tggtatcaca
    22981 tgggaaattg aaaggcgagg aacaccttca aagttagaat ttacaatagt catggatgat
    23041 atattagagt tttgcgaagg taactcagta agattatatt acaaaggtgt aggcatattt
    23101 tatggatata tatttcagaa gaaaagagat aaagaaaatc acattaaaat tgttgcttac
    23161 gaccagctaa gatattttaa gaataaagat acttatgtat atagcaataa aactgcaagt
    23221 gaacttgtaa aaatgttggc taaagatttt aatttaaaat acaatgtcat agaagatact
    23281 aagtataaaa tatctaggat agaagaaaat aaaacactct ttgacatgat actaactgca
    23341 cttgatgata ctttaagaga gaaaaaagaa atgtatatct tgtatgatga ttttggaaga
    23401 ataacattaa agaatgttgc atcaatgaaa ctggatactg tcatgaacaa tgatgtaatt
    23461 gaggattttg actataattc atcaatagat agtgatactt acacaaagat taaacttgtg
    23521 agagataatg aagaaacagg gaaaagagat gtatatattg cacaagactc tacacatatg
    23581 aggagttggg gaatactaca actatttgat acagtagata aaaacatgag tgaagcagag
    23641 ataaagcaaa aatgtgatat acttctaaaa ctatataata agaaaactaa gtcattaagt
    23701 ttaaaaaatg tgttaggaga tattagagta agagcaggtt gttta
//
LOCUS       DAFAZV010000059        23018 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFAZV010000059 DAFAZV010000000
VERSION     DAFAZV010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 23018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23018
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.059"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            343..1179
                     /locus_tag="KOU88_003334"
     CDS             343..1179
                     /locus_tag="KOU88_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK3213186.1"
                     /translation="MNIKKIFNNNVVVSSLEDGTEIIVTGAGVGFKKKVGDLIDENLI
                     SKKYFVQDDQRDKYNQILNKTSIEYFKISEEIIEKANEVLNTQVNDSIILALTSHIEF
                     AVQREKQGIKLPNLILNETKQLYREEFEFGLWAIDEIEKRIGIKLPEDEAGYIAIHII
                     NGLENSQKDEGINILEFSKQVIQIIEEVHGFKLDVNSLNYTRLITHLKFFVQRILRKE
                     TYNDSDIEDMYKLVNKNYNKPKVCTEEIAALVLDRFEYKISKEEELYLMIHINKITNS
                     GC"
     gene            1532..3109
                     /locus_tag="KOU88_003335"
     CDS             1532..3109
                     /locus_tag="KOU88_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK3213187.1"
                     /translation="MKKNKLGLWNFFQMLGKTFMFPIALLSVSGMMLGLGAGFTDPKM
                     IEMVPFLGNEYVNLVLNFMLTIGLFAFNNLGALFAMAIPLGLLKKEKEFGAFSGLVGF
                     IAMHIGTNFYLTRADLLVPAEQMSTNGQAMIMGIQTYNTSVLGGIVAGLIVYAIYDKV
                     SNLKIPESLGFYSGPRLVPIVSLIVMSIVGLLIPIVWPPFFNAFQSLGRWISSAGPLG
                     YFSYAVAERVTIPFGLNHLVTSVFRFTPIGGTAVIDGETYFGTLNMFMAYVENNQIIP
                     LDLAGKMEQGKLMIQYGLAGAALAIYRTAKPENRKALKGLLISGVLTVIIGGISEPIE
                     FLFLFISPALFAFHTFMNGLANMVLPYLGVLMGFTGDLIAFISFGVLRGTATGWPIAV
                     LVAVLYFAIYYFVFKWAIIKFNIKTPGREDKEIKVSEGNGSDFKNLSTYKGQQMISAL
                     GGQSNILSLDNCVTRLRLKLQDVSLINEDAIKEAGGIAVVKLDEYTIQVIIGTQVYSL
                     RKQMDKAMEGHLEACND"
     gene            3102..4286
                     /locus_tag="KOU88_003336"
     CDS             3102..4286
                     /locus_tag="KOU88_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3213188.1"
                     /translation="MINFDKKVDRLGTYCTQWDYVEDRFGKKDLLPFTISDMDLEFPF
                     EITEVLQERLNHRVLGYSRWKHDDFRNSVTNWYIKRFNCSVDSNWIYYSPSVMYSISK
                     LIEMLSNEGDGILINTPAYNAFYDVITNNNRNIIKSHLVNRNGFYSIDFNDFEKKCKK
                     SKIFILCNPHNPTGRVWSELELVKMIGICKNNDVKIISDDIHMDIVYDNRMTPILNVA
                     KDYLDSVFICTSASKSFNIPALTGSYVIIPNEGIRNKFENITRYRDFVNSPAILAILA
                     TMVCYDDCEYWLDELLKYLKENLKYTIDYIKDNLEPLKLVMPEGCYFAWIDFSELKIS
                     GEKFQKLLMDIGEVAIMSGSVYGKEGEFYLRLNVACSREKLEDGLNRIKKTMDYIAKR
                     NL"
     gene            4304..4903
                     /locus_tag="KOU88_003337"
     CDS             4304..4903
                     /locus_tag="KOU88_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK3213189.1"
                     /translation="MGYLKTMVDVMTTEMNAIRCLIDEAGIEYESIVSEIANCEGKVI
                     FMGVGKSAHIGKKLAATFASTGTPSFFVHATEAVHGDLGMIESKDITILISNSGNSME
                     VVNCIKYIKAIGSKTIAFTSNRNSVLAKECDYALIYPAKDEADHLNLAPTTSSTITLV
                     LGDSIACALSKSSNFGSSDFYKYHPGGSLGEKLKTANNG"
     gene            4927..5397
                     /locus_tag="KOU88_003338"
     CDS             4927..5397
                     /locus_tag="KOU88_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3213190.1"
                     /translation="MFKMFKKKSIKSPISGKVIELSKIQDGVFSQKIMGEGVAIDSTG
                     DIVYAPINGKIVVVAETKHAFVIELENGMELLIHVGLDTVNLKGEGFEALVSMGEQVK
                     EGTPMLKINRPLIESKGISLITPVTITNHSEYNMNTCNVGNSVEGGKDTVIEFK"
     gene            5769..6515
                     /locus_tag="KOU88_003339"
     CDS             5769..6515
                     /locus_tag="KOU88_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBK3213191.1"
                     /translation="MKIENLSIDDIKRGYIFNDDLNCYSCIKCTKTYEVGEIYKIGNR
                     FFEASKAIELHVELEHSDYLEQLLNSDSKYNTLTENQKQLFQLFISDLPDKEIAKQVG
                     VSTSTIRHQKFIFREKAKQAKFYLALYESVFEDKSNKSSTIIPIHEHARMVDERYVVT
                     EEERKHILDTSFESMNPLKLKVFSSKEKKKVVILSKILEQFERGKKYSEKEVNQILES
                     IYDDFATIRRYLIEYGFMSRNKECTKYWLT"
     gene            6576..7250
                     /locus_tag="KOU88_003340"
     CDS             6576..7250
                     /locus_tag="KOU88_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBK3213192.1"
                     /translation="MNDELKSILYNKGVDIVRFVDISEFPINQTQGFSKAILFCIGLS
                     KKFITDIYNNLPTDSDEFLEKEEKVEELADWISKYIQNKGYRAYSQSEKNNLEHGYFE
                     KAYINPEMQSGISPLPHKTIANISGIGFMGKNNLFVTEEYGCAFSMCTVLTDAPISVE
                     RYPLIDSKCMDCNVCVENCPAKAIHGNEWTLPGKREFIIDVSKCFCVLKCMMSCPWSL
                     RYANQK"
     gene            7619..8965
                     /locus_tag="KOU88_003341"
     CDS             7619..8965
                     /locus_tag="KOU88_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBK3213193.1"
                     /translation="MEIETKTPDWINVLELNSKIDITGKYDVSNMIQNIVSDKSLEGS
                     IIYFPKGNYLFEKGIKISQQITLQGDSYYGGGNQVSNLDKKQSIIGTTNFITRGVSNM
                     SIITLSGTSQCIKNINFYYDSHDIEKIPPKNVSAITEYGETQGLSHFEHLFISGFSGI
                     GIEIPYYSTGNDITVSSCGLGMRLGEKSMLSSSKIYECKNGMEITTGVSLNNVRIEEI
                     KEIGINNKGFGFNLIMNLMVDQCGYCGFMFEKMYYSQMTARITRCGQYYKSVDYNAYE
                     NMEDRKEEAYSIFYGDILENCNIVLMNSNIDTLENDSLNEHKIYVIKANETNNVMLTC
                     YAEADNFIQCAKGNLLLENGENTYKFYNGEICSVGGVQISDIDEKDLIKIIENTLYID
                     DKGKYLMVPRLKKNTVIYSVLDSTEEINKLHGGIWEYIDAKVLAGESMYYYKKIKD"
     gene            8992..10386
                     /locus_tag="KOU88_003342"
     CDS             8992..10386
                     /locus_tag="KOU88_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBK3213194.1"
                     /translation="MEESIIIKDISGWINVLDYGICNDETKDVSSKLQEIMDAVPEDS
                     IIYFPKGKYLFESGVKIKKRLTLCGDSYILANVPKNTAGVTQFTFKGKKNPKSENIAI
                     ITAKSVRHCIKSICFYSDSCDRDMTSNHEPPTDGKPRFHHNVIINYRNISAIVCEDKQ
                     GESGHYENLSFSGFSGIALDMPNNSTANDITIFTSGLGISTGENSTIANSKVWGCVDG
                     MIISTGTFINGMRVEEIKKVGIKNIGRGLNFITNITIDQCGYCGVWFDSISNVQISGN
                     ITRCGQYYYDVSYDNYLMLDNRVKEAYSLFYGNLLESSNIVLSNTNKDNWEDFKEDKH
                     KVYLVEALETKNVLLTCNIDATDWIVKSEKGNLTYNNMRQTVIFYDGKLSSINGIGIS
                     DEDYGDKVKIKKGNIYINSKDIKMHKPEVGDIISTIIKDKSILSAHYGGTWEKIGEKI
                     EFGITVHYYKLIEK"
     gene            10596..12032
                     /locus_tag="KOU88_003343"
     CDS             10596..12032
                     /locus_tag="KOU88_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 55 protein"
                     /protein_id="HBK3213195.1"
                     /translation="MEGRTGIKDGRWINVVERGIKNDGSYNVGPALQDIIDEIETDFC
                     VLYFPKGKYLFTSGVKINKEIVLQGDSNSSTGTTQFITRGVENMSIITLTGKKQCIKN
                     INFYSDSCEIQVNEEPPTKGNPKYHYEMIINKNEKNVEMNNVSAILYDNSKDMIKGLG
                     HYENIYISGFSGTGIRIPYYSIVNDITVSSCGLGIDTGIDTIISNSRISKCQNGMRIR
                     TGTSINNVRIEKIQKVGLISSQVKGYEGYGSYKINNITIDQCGYCGFSFDSMKDSYFS
                     GIIRRCGQYYYNTDYDTYLSIKDRVEEAYSLFYGNYFTECNIDLVSDNKDNWDDGLEY
                     KHKVYVFKTLQIPKLTLRCNIDAYDYIVKSVHGGGNLMLKNNFNNYIFIDSSSPEVIN
                     GINFNYQKNGNLLRLNNGKLSYKNGKEETAIFRPNYGLIVASTDSECEQIEATYGEKW
                     EKLGSEVIGKETVYYYKHHEPEKTNQIQ"
     gene            12376..13320
                     /locus_tag="KOU88_003344"
     CDS             12376..13320
                     /locus_tag="KOU88_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1848 domain-containing protein"
                     /protein_id="HBK3213196.1"
                     /translation="MIVSVSRRTDIPAFYSKWFFNRLKEGFVYVINPMNPKQVSKIEL
                     NPHTVDCFVFWTKDVTPMLYDLNKLKDYKYYFHYTITSYGKEVETCILDKRKVIDSFK
                     ELSRKIGKERVILRYDPIFLSEKYTVDYHIKAFASLCNQLDGFTEKCIISFIDLYKKT
                     KFNTKALHIKPIEITEIETLSKEISKIAHKHGIILEMCSEEYNLSKFGIGKSKCIDDR
                     LISKIIGCEVEVKKDSTQRDICGCVKSVDIGQYNTCRHYCLYCYANFNYAKVEENCRF
                     YKEDNKLLIDTLRDDAKISIRDMKTIKVDKNKQISIFD"
     gene            13489..14421
                     /locus_tag="KOU88_003345"
     CDS             13489..14421
                     /locus_tag="KOU88_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBK3213197.1"
                     /translation="MNLLKKYPIPIASLILSIFTLGNLLQSYSESLRNVIGFIGFILY
                     AIYIVKIILLRKGVKEQLENPLISSTFPTITMATMIFATYIKPLSLELSIMIWSIGIV
                     GHLVLIVLFSKKFLVKFSIKTVFPSWYIVYVGIVAASVTAPAFNQLLIGKIAFWIGFV
                     SYIVLIPVILKRVWIIKEMPEPSLPSIAILAAPGSLLLSGYINSFSDKNNVVLYLLFI
                     LSIVFYIIVLGYLPKLLRLPFYPSFAAFTFPMAISAMGMKLMNGYLTKSGHFISWISY
                     ASKLEEIIATVIILYVLVLFIIYLSKSETTSKAK"
     gene            14526..14993
                     /locus_tag="KOU88_003346"
     CDS             14526..14993
                     /locus_tag="KOU88_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C_GCAxxG_C_C family protein"
                     /protein_id="HBK3213198.1"
                     /translation="MKTKEEYLKEVRNISEEYFRKGEFFCSEAVLQTINDALGQPLSP
                     EITKLASGFPIGLGKAQCLCGAISGGEMALGIVYGRVHGEAMNPKMFEHAKGLHDYIK
                     KEYGATCCRAITKKWDGDNFMSPERKEHCIKITGQVTEWVADKLIEDEKLNIK"
     gene            complement(15237..16091)
                     /locus_tag="KOU88_003347"
     CDS             complement(15237..16091)
                     /locus_tag="KOU88_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009912760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar uptake protein"
                     /protein_id="HBK3213199.1"
                     /translation="MLTIIIALLPVMGWGLMPIVANLKKSSPHEQLLGTSISAFIFST
                     IITLVIHPEITFFSFCISMISGIFWSLGQLMQFKAIQIASVSKVMPISNGSQLTFTTL
                     LAVILFNEWTSFKMLLIGSLSILCIILGILLTNYQTKKSTDKNMLKCVGVVLLSSLFL
                     SLYVVTNQIFLIEGYRIILPQSVGMLITSYIIVKYFSKEIVYRENVLFNLITGILWSI
                     ANLGMFITTNTLGVTISFSISQSCVIVATLGGIIFFKEKKNKKEWLAIFIGIILIMSG
                     VLMLSIIK"
     gene            16257..18221
                     /locus_tag="KOU88_003348"
     CDS             16257..18221
                     /locus_tag="KOU88_003348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3213200.1"
                     /translation="MLTDMIQNREIKIIKFLLKEGHTTVKAIADDLDVSEKTVSKSLK
                     EVEAVLKKIGLSLIRKPKIGVYIDGDLKKILPYLDNKGSQIPTTREERVIYIYSVLLK
                     SNDYITIQQLSDELYISRGTIERDLAEVEKLLKNEGISIYKKPSKGIKLNISERDKRQ
                     LTAKFIHKFWSRNWYIKQEQESFYQAFEKIQADVNGIFSEDDLSIIIDILRNFSRERK
                     FEFSDYEFQSLVIHLAIAVERIRKGEYIEESLYIGNIENNQMSNTNYLAKQLEEKFSI
                     LLPKSEIGYINLHLVAADQHRDTNELKNTSANPCETSTNNISNLREIIKNTLYETAYD
                     KDLIDGLTSHVHSSINRLKYGLSIKNPYVNTIKQNFSLSFEQALDLKKVIEFIYDIRI
                     NDDECAYIALHFEAFRERMKELPQNIRVILVCSTGLGSSRLLSARIKKYFPMIKIEKV
                     LSVQELVSSKIDADLVISTIYLELETIPTIVVSPILNESDIRTLERNIQNVSSCTSKK
                     YKSFRNLIFEENILLNIEASNYEDAINHITDNLIKKGFAKEGIAKSAIERENLSYTSF
                     QSIATPHANPSYIKKSNISVATLKNPITWGNEKVEVIFFISLENDKNLELDEIYEVFY
                     DFIDNKKNINDILSATSTKEVYDLLVEESI"
     gene            18221..18682
                     /locus_tag="KOU88_003349"
     CDS             18221..18682
                     /locus_tag="KOU88_003349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3213201.1"
                     /translation="MKISDVLKKEQIVFNLDTNTKEETIKKLSSIFVENGIVDNEEEY
                     VKSVLEREEHSTTGIGNGIAIPHGKSNAVKKSSIIFAKTKHKIEWDALDEKPVDSIFL
                     LAISNIDKDSNHLVLLSKLATKLMDDDNVDALKLANSEQEIINIFSEEGEM"
     gene            18685..19005
                     /locus_tag="KOU88_003350"
     CDS             18685..19005
                     /locus_tag="KOU88_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBK3213202.1"
                     /translation="MKRKIIAVTACATGVAHTYMAAQALKKASKKMGHLIKVETQGAT
                     GIDNELTTKDAQIAEVVIFAVDTKVRNAERFEGKEILEVPVNAPIKDAEKVINDALKL
                     IDTK"
     gene            19021..20121
                     /locus_tag="KOU88_003351"
     CDS             19021..20121
                     /locus_tag="KOU88_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBK3213203.1"
                     /translation="MLKKIVSELKKHVLTGISYMIPLVIAGAMIMAISRVGGSFYNIP
                     DIWDAKYAESASSIVRLLHDLDGFGGTALGLMFPVIAAFIGFSIADKLAIVPGLVGGM
                     IAKDIGAGFLGALAVGLIAGYTCLFIKNHVKLPKSAASIVPIFIVPVFGTLITVVLIN
                     YVIGIPFATLNTGLENWLNGLSGTNQILMAAIIGAMMAVDLGGPVNKAALTTSLALLT
                     SGIYAPNTAAMVGIVIPPLGLGLATILAKQKYNKQLREAGKSSLIMGLIGVSEGAIPF
                     AVESPLKVIPSCVIGTAIASAMAVGLGSVNATPISGFYGWFTVENWPMYVLSIAVGTV
                     IVAGLVIVLRGNPVIEDDEFEDDDFDEAEWES"
     gene            20241..22841
                     /locus_tag="KOU88_003352"
     CDS             20241..22841
                     /locus_tag="KOU88_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBK3213204.1"
                     /translation="MIKAHIVNHTHWDREWYFTSGDALVLSEQLFTDVIDELERNPDV
                     SFVLDGQLSILDDYVQLHKEKIEIIKKLIKEDRLHIGPWFTQTDAFFARGESILRNLM
                     IGIFESKKYGKYMKIGYLPDTFGFNAQMPILLKHVGLDNIFFWRGIHLGKQVQSPYFK
                     WKSLNGESYIYAVNMPHGYGTGMLLEPSLKYVNGRLDPAIDFIKSYTDVDEVLIPSGN
                     DQLNIIGDFKNKIKAINDIGKYSYITSSYQEFLKYIKSIESLESYRGEFREPVLARIH
                     KSIGSSRMDIKLACDKLENKLIKRIEPLLVIAKKSKIEISNQLLINTWKKLLEGQAHD
                     SLAGCVTDTVTDDILHRIREANEICDSIENTIVKKISEGLKLSKNDILVFNTEAKRFN
                     GYKEIQVVSDSKNIYFKDNLDATIIEETYVKPRENVLEETPAGNIFIEEPGYYILKVR
                     INVQLPALGYKVVSFELSDKEMVSLDKSNDTFISNDNYKIIYEDGSLNLQLKDGTYIS
                     NFLTLKDSGNAGDTYDFSPLKNDENIKLSFDKVYTEKALGYEKMVVKGTTLLPLTLED
                     RKNKYLNGKLNVKVSIVLSKENPLMDVKLCVDNTIYNHRLRVHIKTDIKDNKNIASLP
                     FGYITRKNGVLDNWEDIYSEMPIDLEPLESNITLTNQNRSCTVFTRGIKEYQHIEDEI
                     ALTLLATTDELGKPDLLYRPGRASGDTTKKGHIRIKTDKAQMLKELEFSFAIYMDSKS
                     FDELEIANLTHNYLRECVNYQLQDYNFFLYRIDNKIQKSIVNKTVSRELEIISLPENY
                     LISACYPSYYSKDKFIIRVENPSSNRMILDEQIFKNRNGKIVNAIEDVEEEQVYEIAP
                     FDVISILLDL"
BASE COUNT         9040 a         2365 c         4059 g         7554 t
ORIGIN      
        1 aaagattagt acaaaactat aatcttaatt tcaataaata tatatataat taagttgaaa
       61 tacttgaaaa tactggaaaa aattgaaaat aatttttgta atataaaatg tcgattgatt
      121 ttaaataatt aaatatacat aagaaataat taaatatctt tcaatgaaaa tatgataaaa
      181 tatgacaaat taattgatga caataaaaaa tattttgtta ttgtagtatt atagggtaaa
      241 ttgcaaaata tatacgaaag taaaatttta aatattgaca ttaaattaaa tatactatac
      301 tatgtaagtg tgatgagaga atttttttag aggggattta tagtgaatat aaaaaagata
      361 tttaataaca atgtagtagt aagctcccta gaagatggca cagaaataat tgtcactggt
      421 gctggagtag gatttaagaa aaaagtaggc gatttgatag atgaaaattt gatttctaag
      481 aaatattttg ttcaagacga tcaaagggac aaatacaatc aaatacttaa taagacctct
      541 attgaatact ttaaaatttc agaagaaatt atagaaaagg ctaatgaagt tttaaatact
      601 caagtgaatg attcaataat attagcctta actagtcaca tagaatttgc tgtccaaaga
      661 gaaaaacaag gtataaaatt accaaactta atattgaatg agacaaaaca actttatagg
      721 gaagaatttg aatttggatt atgggcaatt gatgaaattg aaaaaaggat aggaataaaa
      781 ttgcctgaag atgaagcagg atatattgct attcacataa tcaatggttt ggaaaattct
      841 caaaaagatg aaggtattaa tatactagag ttttcaaaac aagttattca gataattgaa
      901 gaagtacatg gatttaaatt ggatgtaaat tcattaaatt atactagact tataactcac
      961 ttaaagtttt ttgttcaaag gattctccga aaagaaactt acaatgatag tgatattgaa
     1021 gatatgtata agttagtgaa taaaaattac aataaaccta aagtgtgtac tgaagaaatt
     1081 gcagcattgg tattagacag atttgaatat aagattagta aagaagaaga attatattta
     1141 atgattcaca taaataaaat aacaaacagt ggttgttagg attgtaactg ataaagcagg
     1201 caaaacctaa gtcattgagc ttaactatta gattaagttt tttgatttag gtttttttat
     1261 tagatacaat caaaatacag acagtgactt ttaggattgt aactggttaa gcaggcaaaa
     1321 cctaaatcat tgaatttaac tattaggtta agttttttga tttaggtttt tttattagat
     1381 acaatcaaat acagacagtg acttttagga ttgtaactgg ttgagcaggc aaaacctaaa
     1441 tcattaaact taattattaa attaagtttt ttgatttagg tttttctata aatttgatta
     1501 tgtttttaga taaaaatagg aggggaaaat tatgaaaaaa aataagttag gtttatggaa
     1561 cttcttccaa atgttaggaa aaacgtttat gttcccaata gcactactta gtgtttctgg
     1621 gatgatgcta ggacttgggg caggttttac agaccctaag atgattgaaa tggttccatt
     1681 tttagggaat gaatatgtta acttagtttt aaacttcatg ttaacaatag gattatttgc
     1741 atttaacaac ttgggagcat tatttgcaat ggcaattcca ctaggattat taaaaaaaga
     1801 aaaagagttt ggtgcttttt caggattagt aggatttata gcaatgcaca taggtacaaa
     1861 tttttattta acaagagctg atttgttagt accagcagaa cagatgtcaa ctaatggtca
     1921 agctatgatt atgggtatac aaacatataa tacaagtgtt ttaggtggta ttgtagcagg
     1981 attaattgtt tatgcaatat atgataaagt tagtaattta aagataccag aatcattagg
     2041 attctacagt ggaccaagat tagttccaat tgttagttta atagtcatga gtatagttgg
     2101 attattaata cctattgttt ggccaccatt tttcaatgca ttccaaagtt taggaagatg
     2161 gatttcttca gcaggaccat taggatattt ttcatatgca gtggcagaaa gagttacaat
     2221 tccatttgga ctaaatcatc ttgtaacatc cgtattccgt tttacaccaa taggtggaac
     2281 tgctgttatt gatggagaaa cgtactttgg tacattgaac atgtttatgg catatgtaga
     2341 aaataatcag attatacctc ttgatttagc tggtaaaatg gaacaaggta aattgatgat
     2401 tcaatatgga ttagctggtg ctgcattggc tatctaccgt acagcaaaac cagaaaatag
     2461 aaaggcactt aaaggacttt taatatcagg agtgttgaca gttattatag gtggtataag
     2521 tgaaccaata gagtttctat tcttattcat atcaccagca ttatttgctt tccatacatt
     2581 tatgaatggt ctagcaaaca tggtacttcc atacttaggc gtgttgatgg gattcacagg
     2641 agatttaatt gcatttataa gttttggtgt gttaagagga acagctacag gatggccaat
     2701 agcagtatta gtagcagttt tatattttgc aatatactat tttgtattta agtgggcaat
     2761 tattaagttt aatataaaga ccccaggacg tgaggataaa gaaataaaag tatctgaagg
     2821 aaatggttca gatttcaaaa atttgtctac atataaagga caacaaatga tatctgcttt
     2881 aggtggtcaa tctaatatat tatcactaga taattgtgta actagattgc gtttaaaact
     2941 acaagatgta tcattaataa atgaggatgc aattaaagag gctggtggta tagcagttgt
     3001 taaattagat gagtatacaa tacaagtaat tataggaact caagtgtatt ctttaagaaa
     3061 gcagatggat aaagctatgg aaggtcattt ggaggcatgt aatgattaat tttgataaaa
     3121 aagtagaccg attgggtaca tattgtaccc agtgggacta tgtagaagat agatttggta
     3181 agaaggattt gcttcctttt acaatttcag atatggattt agagtttcca tttgaaataa
     3241 cagaggtgtt gcaggaaagg ttaaatcata gagttttggg atacagtaga tggaaacatg
     3301 atgattttag aaattcagtt acgaattggt atattaaaag atttaattgt agcgttgata
     3361 gtaactggat atattatagt ccaagtgtaa tgtattcaat tagcaaactt attgagatgt
     3421 taagtaatga aggagatgga atccttataa atactcctgc atacaatgct ttttatgatg
     3481 tgataacaaa taacaatcgt aatattataa agtcacatct tgtaaatagg aatggattct
     3541 attcaattga ttttaatgat tttgagaaaa agtgtaaaaa atctaagata tttattttat
     3601 gtaatcctca caatccaact ggtagagtat ggagtgagtt agaacttgtt aagatgatag
     3661 gaatttgtaa gaataatgat gtcaagataa tatcagatga tatacacatg gatattgtat
     3721 atgacaatag aatgacacct atcttaaatg ttgcaaagga ctatttagat tctgtattca
     3781 tttgtacatc agcgtctaaa tctttcaata taccagcatt gactgggtca tatgtgatta
     3841 taccaaatga aggtattaga aataaatttg aaaatatcac tagataccgt gattttgtaa
     3901 attcgccagc aattctagca atattagcta caatggtctg ttatgatgac tgcgaatatt
     3961 ggttagatga actattaaaa taccttaaag agaatcttaa atatacgatt gattatataa
     4021 aagataattt agaaccattg aaattggtca tgccagaagg ctgttacttt gcttggatag
     4081 atttttccga acttaaaata agtggtgaga aattccaaaa attattgatg gatattggag
     4141 aagttgctat tatgtcgggg tctgtatatg gtaaagaagg tgagttttat ttaaggttaa
     4201 atgtggcatg ttcaagagaa aaacttgaag atggtttaaa taggattaaa aaaactatgg
     4261 attatattgc aaaaagaaat ttatagtagg aagggagata gttatgggat atttaaaaac
     4321 aatggttgat gttatgacta ctgaaatgaa tgccataaga tgtttaatag atgaggcagg
     4381 aatagaatat gaaagtatag ttagtgaaat tgcaaattgt gaaggcaaag taatttttat
     4441 gggtgtagga aaatctgcac atataggtaa gaaattggca gctacatttg ctagtactgg
     4501 tacacctagc ttttttgtac atgcaacaga ggcagtgcat ggagatttag gaatgattga
     4561 aagtaaggat attacaattt taatatcaaa tagtggaaat tctatggaag tggtaaactg
     4621 tataaaatat attaaagcaa taggttctaa gacaattgca tttacttcaa acagaaattc
     4681 agtactggca aaagagtgtg attatgcttt aatatatcct gcaaaggatg aagcagacca
     4741 tttaaatcta gcaccaacaa catcatctac aattactttg gttttaggag attctattgc
     4801 atgtgcatta tctaagagta gtaattttgg ttcttcagat ttttataagt accatccagg
     4861 aggaagttta ggtgagaagt taaaaacagc taacaatgga taaaagcaaa aaggagagta
     4921 gtttttatgt tcaaaatgtt taaaaaaaaa tcaataaaat cacccatatc aggaaaagta
     4981 atagagttat ctaaaataca agatggtgta ttttctcaaa aaattatggg agagggtgta
     5041 gctatagatt ctacaggaga cattgtgtat gctccaatca atggaaagat agtagtagta
     5101 gcagagacta aacatgcatt tgtaatagaa ttagaaaatg ggatggaact tcttattcat
     5161 gttggtttag atactgtaaa tttaaaaggc gaaggttttg aggcattggt gagtatggga
     5221 gaacaagtga aggaaggaac accaatgttg aaaattaacc gtcctttgat tgaatcaaag
     5281 ggtatatcac ttattactcc agttacaata actaatcatt cagagtacaa tatgaataca
     5341 tgtaatgtag gcaatagtgt tgaaggtggg aaagatactg taattgagtt taaataaaga
     5401 actaaaatac aaggttaata tttataaata cctataaact tatgctttat aagattgatt
     5461 gtatagattt gttgtataga tttgttgtat aaaaaagaac tctttaatta taaattaagg
     5521 agttcttttt tattttgtaa atattgttta gatttatata gaaaaacact tagtaataaa
     5581 tagaataaat aagtatttat atagctaaaa atctaaatag ttttgtttaa atatattttt
     5641 atattttgta atttcaaatt aataaataat tagatttgat aaacaaaaaa taaaaatgtt
     5701 gattacatta ataaacttta atataatata tttatgaaaa atgtaaactg tgaaatggag
     5761 gtagtaacat gaaaattgaa aatctttcta ttgatgatat taaacgaggc tatatattta
     5821 atgatgattt aaattgttat agttgcatta aatgtacaaa aacatatgag gtaggagaaa
     5881 tatataaaat aggtaataga ttctttgaag cttcaaaagc tattgaactt catgtggaat
     5941 tagaacatag tgattattta gagcaattgc ttaatagtga ttcaaagtac aacacattga
     6001 ctgaaaatca aaaacaatta tttcaattat ttattagtga tttaccagat aaggagatag
     6061 caaaacaggt tggagtatcc acatctacta tacgccatca aaaatttatt ttcagagaaa
     6121 aagcaaaaca ggctaagttc tatttagcac tatatgaatc tgtatttgaa gataaatcta
     6181 ataaaagtag tactataata ccaatccatg aacatgctcg aatggtagat gaaagatatg
     6241 tagtaactga agaagagaga aaacacattt tggatacatc atttgaaagt atgaatcctt
     6301 taaaattaaa agtattttct tcaaaagaaa agaaaaaggt cgtaatttta tctaagattt
     6361 tggaacaatt tgaacgtggg aagaaatatt cagaaaagga agttaatcag attttagaat
     6421 ctatatatga tgattttgca acaattagaa gatatctaat tgagtatggt tttatgagta
     6481 gaaataaaga atgtacaaag tattggttaa cataattaaa ataataaatt ttactaatgt
     6541 gtaatgttat ttttatctag ggggaggagt caaatatgaa tgatgaatta aaatctattt
     6601 tatacaataa aggtgtagac attgttcgct ttgttgatat atctgaattt ccaataaatc
     6661 aaacacaagg tttttctaaa gcaattttat tttgtatagg gttatcaaaa aaatttatta
     6721 cagatatata caataactta cctacagata gtgatgagtt tttggaaaaa gaggagaaag
     6781 tagaagaatt agctgactgg atttcaaaat atattcaaaa taaaggatat agagcatatt
     6841 ctcaatcgga gaaaaacaat ctagaacatg gatattttga aaaagcctat attaatccag
     6901 aaatgcaatc agggattagt cctttaccac ataagacaat agcaaatatt agtggcattg
     6961 gatttatggg aaaaaataat ttgtttgtaa cagaggaata tggatgtgct tttagcatgt
     7021 gtacagtact tacagatgct ccaatttctg ttgaaagata tcctttgatt gattcaaaat
     7081 gtatggattg taatgtttgt gtagaaaact gccctgcaaa agctatacat ggaaatgagt
     7141 ggactttgcc aggaaaaaga gagtttatta ttgatgtttc aaagtgtttt tgtgtattga
     7201 agtgtatgat gagttgccca tggtcattaa gatatgcaaa tcaaaaataa ttttactaga
     7261 gaaggtatta aattgaatat tataaaattt ttaaaatgta agattatata agatttttca
     7321 aaataaaaat ttgtatagaa cactcagaaa tgagtgtttt tttattggga ttaaattata
     7381 ttgatacaaa gcttaactat tttaatcatt atataaaatt tgtattaaaa aattaagaat
     7441 aacttggtaa tagtgaaaat ataatgagat tataattgat ttataatata actataatga
     7501 tattgtaaaa atgaaaattg tcctctcaaa attcccaaag agagtaaaag tcacttcagt
     7561 tatagtcaaa aaaatttttc tgtgaaaaga atttagattt gaaaaggagg aattaatcat
     7621 ggaaattgaa actaaaactc cagattggat taatgtacta gaattaaaca gtaaaataga
     7681 tattactggg aaatatgatg taagtaatat gatacaaaat attgtctctg ataagtcact
     7741 agaaggttcc attatatatt ttccaaaagg taattactta tttgagaaag gtattaaaat
     7801 tagtcaacaa ataacacttc aaggagattc ttattatgga ggaggtaatc aagtatcaaa
     7861 tttagataaa aaacaatcaa tcataggaac aaccaatttt ataacccgag gagtttctaa
     7921 tatgagtatt attacattgt caggaacaag tcaatgtatc aaaaatatta atttttatta
     7981 tgatagtcat gatatagaga aaataccgcc taaaaatgta tctgctatta cagaatatgg
     8041 agaaacacaa ggactatctc attttgaaca tctgtttatt tctggatttt cagggatagg
     8101 aattgaaatt ccatactatt caactggtaa tgatattact gttagttcat gtggtcttgg
     8161 tatgaggctt ggagagaagt caatgctttc tagtagcaag atttacgaat gtaaaaatgg
     8221 aatggagatt actactggtg ttagcttaaa taatgtgaga atagaagaaa taaaagaaat
     8281 aggtattaat aataaaggat ttggttttaa tctgattatg aatcttatgg tcgaccaatg
     8341 tggatattgt ggatttatgt ttgaaaaaat gtactatagt cagatgactg ccagaattac
     8401 tagatgcggt cagtattata aaagtgttga ttataatgct tatgagaata tggaagatag
     8461 aaaagaagaa gcttattcca ttttttatgg agatatttta gaaaattgca atattgtatt
     8521 gatgaatagt aatattgata ccttggaaaa tgattcactt aatgaacata agatatatgt
     8581 aatcaaggca aatgaaacaa acaatgtaat gctaacatgt tatgctgaag cagataactt
     8641 tatacaatgt gcaaaaggta acttgctgtt agaaaatggt gaaaatactt ataaatttta
     8701 taatggtgag atttgttctg taggaggtgt tcaaatttct gatatagatg aaaaagattt
     8761 aatcaaaata atcgagaaca ctctgtatat agatgataaa ggtaagtatt taatggttcc
     8821 tagattaaaa aagaatactg taatatattc agtactagat tctacagaag aaataaataa
     8881 attacatggt ggaatatggg aatatattga tgcaaaagta ttagctgggg aatccatgta
     8941 ctattataaa aagataaaag attaaattat caaactagga ggtagtgatt aatggaagag
     9001 tctataataa ttaaagatat aagtggctgg attaatgttc ttgattatgg aatttgtaat
     9061 gatgaaacaa aagatgtaag ttccaagttg caagagatta tggatgctgt accagaagat
     9121 tctattatat attttccaaa aggaaaatac ttatttgaaa gtggtgttaa gattaagaaa
     9181 cgattaactt tatgtggaga ttcttatatt ttggcgaatg ttcctaaaaa tactgctgga
     9241 gtaacacaat ttacttttaa aggaaagaaa aatcctaaaa gtgaaaatat agcaattata
     9301 acagcaaaaa gtgtaagaca ctgtattaag agcatttgct tttattcaga tagttgtgat
     9361 agagatatga catctaatca tgaacctcca acagatggaa aacctagatt tcatcataat
     9421 gtaattataa attatagaaa tatatcggcc attgtatgtg aagataaaca gggagaatca
     9481 ggtcattatg aaaatctatc ttttagtggt ttttctggaa ttgcacttga tatgcctaat
     9541 aattctacag caaatgatat tacaattttt acatccggac ttggaattag tacaggagaa
     9601 aattcaacta ttgctaacag taaggtttgg ggctgtgttg atggaatgat aatttctact
     9661 ggaactttta taaatggtat gagggtagaa gaaataaaaa aagttggaat taaaaatatt
     9721 ggtagaggtt taaattttat tacaaatatc acaattgacc aatgtggata ttgtggagtt
     9781 tggtttgatt ctatatccaa tgttcagata tcaggaaata tcacaaggtg tgggcagtac
     9841 tattatgatg taagctatga taattattta atgttggata atagagttaa agaagcatat
     9901 tctttattct atggtaattt attggaatca agtaatatag ttttatcaaa taccaataaa
     9961 gataattggg aagatttcaa agaagataag cataaggtgt atcttgtaga agcacttgaa
    10021 accaagaatg tactattaac atgcaatata gatgctactg actggattgt taagtcagaa
    10081 aaaggaaatt taacgtacaa taatatgcga caaactgtta tattttacga tggaaaacta
    10141 agtagtatca atggaattgg tatatctgat gaagattatg gggataaagt caagataaaa
    10201 aaaggaaata tatatataaa tagtaaggat attaagatgc ataaaccaga ggtaggtgac
    10261 attatctcaa caattattaa agataaaagt attctttctg ctcattatgg gggaacatgg
    10321 gagaaaattg gtgaaaaaat agagtttgga ataactgtac actattataa attgatagag
    10381 aaataagtaa atacgtagta tttgaataga tgtattttat tggagagcta ggactatagt
    10441 tttaatgtaa attgtttggt aatagcatgg attgaataat ataaaaataa tataaaaaat
    10501 taatttgatt atgtaaattt ctatgaagta gtaaaactgt gactttagtc ataggaggtt
    10561 caaactaagt aaaagggaaa ggaatatata atattatgga aggaagaact gggattaaag
    10621 atggaagatg gattaatgta gtagaaagag gtattaaaaa tgatggttcg tacaacgtag
    10681 gtcctgcttt gcaggatatt attgatgaaa tagaaacaga tttttgtgtc ttatattttc
    10741 caaaaggtaa atacctattt acaagtggtg ttaaaattaa taaagaaatt gtattgcaag
    10801 gtgattctaa ttcatctaca ggtactacac aatttataac tcgtggagta gaaaatatga
    10861 gtattattac attgacaggg aagaaacaat gtattaaaaa tataaatttc tattctgata
    10921 gttgtgagat acaggtcaat gaagaaccac cgacaaaagg taatcctaaa tatcattatg
    10981 agatgattat caataagaat gaaaagaatg ttgagatgaa caatgtatca gcaatcctgt
    11041 atgataacag taaggatatg attaaaggtc taggtcatta tgaaaatatt tatataagtg
    11101 gtttttcggg tacaggaatt aggataccat attactcaat tgtaaatgat attacagttt
    11161 catcctgtgg gctgggtatt gatacaggaa tagacacaat tatttctaat agtaggatat
    11221 ctaagtgtca aaatggaatg aggattagaa ctggaactag tataaataat gtaaggattg
    11281 aaaaaataca gaaagttggt cttataagta gtcaagttaa ggggtatgag gggtatggaa
    11341 gttataaaat taataatatt acgattgacc aatgtgggta ttgtggcttt tcatttgatt
    11401 caatgaaaga tagttatttt tctggtatta taagaaggtg tggtcagtat tattataata
    11461 cagattatga cacatattta agtattaaag atagagtaga agaagcatat tctttatttt
    11521 atggaaatta ttttacagaa tgtaatattg atttagttag tgataataag gataactggg
    11581 atgatggctt agaatataaa cataaagttt atgtatttaa aacccttcaa ataccaaaat
    11641 taacattgag atgcaatata gatgcctatg attatatcgt taaatcggta catggaggag
    11701 gtaatttaat gttaaaaaat aactttaaca attatatatt tattgattca tctagtccag
    11761 aagttattaa tggaattaat tttaattatc aaaagaatgg aaacctgtta aggttaaata
    11821 atggtaaatt aagttataaa aatggaaagg aagaaacagc tatattcaga cctaattatg
    11881 gtcttattgt agcatcaaca gattcagaat gtgaacaaat agaggctacc tatggagaaa
    11941 aatgggagaa gcttggttct gaagtaattg gaaaagaaac ggtatattat tataaacatc
    12001 atgaaccaga aaaaacaaac caaatacaat aaaatttgta ttatataatg atataaagtt
    12061 ttaatatata gtgtttacct ttaatgtaat attgatatat ttgtatagta ttaaatttgt
    12121 taaaaagtaa aattgtaggg tgcttgaaaa tagcaccttt tttagtttca ttataaaatt
    12181 agttttgaaa gtttaggaat aatgtatatt tatttttaaa gaattataac tttattaagg
    12241 atattttaaa tgctagaaat gaatcagtaa atcatactgg aattatctta aatgttttga
    12301 ttaaattaag tatttagagc tataattata ttaaaaatat attagaacat aattatatta
    12361 ctatggaggt taaatatgat agtaagtgtg agtagaagaa ctgatatacc tgctttctat
    12421 agtaagtggt tttttaacag acttaaagaa ggttttgttt atgtaattaa tccaatgaat
    12481 ccaaaacagg ttagtaagat agagctaaat ccacatactg ttgattgttt tgtattttgg
    12541 acaaaggatg taactccaat gttatatgat ttaaataaat taaaagacta taaatattat
    12601 tttcactata ctataacatc atatggaaaa gaagtagaga catgtatttt agataaaaga
    12661 aaggtaatag attcatttaa ggaattgtct agaaaaatag gcaaagaaag agtaatttta
    12721 agatacgacc cgattttctt aagtgaaaag tacacagtag attatcatat caaagcattt
    12781 gcgagtttat gtaatcagct tgatggattt acagaaaaat gtataataag ttttatcgat
    12841 ttgtataaga aaacaaaatt taatactaaa gcattacata taaagccaat agaaattaca
    12901 gaaatagaaa cattatcaaa agagatttct aagattgctc ataagcatgg gataatactt
    12961 gaaatgtgtt ctgaagaata taatttaagt aaatttggga ttggaaaaag taagtgtatt
    13021 gatgatagat taatatcaaa aattatagga tgtgaagtag aggtaaaaaa agatagtaca
    13081 caaagagata tttgtggatg tgttaaaagt gtcgatatag gacaatacaa tacttgcaga
    13141 cattattgtc tgtattgtta tgctaacttt aattatgcaa aagtagaaga aaactgtagg
    13201 ttttataagg aagataataa attactcata gatactttaa gagatgatgc aaaaataagc
    13261 attagagata tgaagactat taaagtagat aagaataaac aaattagtat atttgattaa
    13321 aataaatata ctaattacct taatatatta agaatataga tacttttgat aacaaaatta
    13381 aacttaatag atattttcta tataagaaag atggtcataa tatgtcaatt tgaccatctt
    13441 tttgatataa ttaaaacaca aataatttag taacaaagga ggcagaactt gaatttatta
    13501 aaaaaatatc ctatacctat tgcaagtttg attttatcaa tttttacttt aggtaactta
    13561 ttacaatctt atagtgaatc attacgtaat gtaattggat ttataggatt tattttgtat
    13621 gcaatttata tagtcaaaat aatattactt agaaagggtg ttaaagagca attagagaac
    13681 cctttaatat caagtacatt tccaactata acaatggcaa caatgatatt tgctacatat
    13741 ataaaaccat tatctttaga attaagtatt atgatttgga gcataggaat tgtgggtcat
    13801 cttgtgttaa tagtcttatt tagtaagaag ttcttagtta aattctcaat aaaaacggta
    13861 tttccatctt ggtatatagt atatgttggg atagttgcag ctagtgttac ggcaccagca
    13921 tttaatcaac ttttgattgg caaaattgct ttttggatag gatttgtatc ttatatagtt
    13981 cttataccag taattttaaa gagagtatgg ataatcaagg aaatgcctga accatcttta
    14041 ccaagtatag ctatattagc tgcaccaggg tcactattat tgtctggata tattaattct
    14101 ttttcagata aaaataatgt agtattatac ttgttattta tattatcaat tgtattttat
    14161 attatagttt tgggatattt accaaaatta ttaagattgc ctttttatcc gagttttgct
    14221 gcatttacat tccctatggc aataagtgca atgggtatga aactaatgaa tggttattta
    14281 actaaatcag gtcattttat aagttggatt tcatatgctt ctaagttaga agagataatt
    14341 gctacagtga ttattttata tgttttagtt ttgtttatta tatatcttag taaatctgaa
    14401 actacatcta aagctaaata agaattatta aatatgtgta tttaatagga atattgatat
    14461 aaatatatga agataagata aaccatagaa acttaattta gcttaatttt attggaggaa
    14521 aacaaatgaa aacaaaagaa gaatatttaa aagaagttag aaacatatca gaagaatatt
    14581 ttagaaaagg agagtttttt tgctctgaag cagttctcca gacaataaat gatgctttag
    14641 gccaaccttt aagtccagag ataactaagt tagcatcagg atttccgata ggacttggaa
    14701 aggcacaatg tctttgtgga gcaatatctg ggggagagat ggctttaggt atagtatatg
    14761 gaagagttca tggtgaagct atgaatccaa agatgtttga gcatgctaaa ggtttgcatg
    14821 attatattaa aaaagagtat ggtgcaacat gttgtagagc tattacaaag aaatgggatg
    14881 gtgataactt tatgtctccc gaaagaaaag agcactgtat taaaataaca ggtcaagtta
    14941 cagagtgggt tgcagataag cttatagaag atgaaaaact taatatcaaa tagtgtaata
    15001 ttagttggtg aatttataaa gttaaattta cttatagtat aagatacttg atattctcgt
    15061 attgatagaa aaatttatag catatgtatt taatgaaata tacttatatt tagagtgtgg
    15121 tttaatttca taaatacata tgctattatt ttaagtatat aagcaaattt atttaaataa
    15181 atagaaacag ttaatttata tgtacaaaac tatatatgat tagtgtaaat aaatacctat
    15241 tttataatac tcaacataag gacaccagac atgattagta ttataccaat aaaaatagca
    15301 agccattctt ttttgttctt cttttcttta aaaaatataa tccctcctaa agtggctact
    15361 atcacacaac tctgagagat agaaaaactt attgtaactc ccaatgtatt agtcgttatg
    15421 aacataccta aatttgctat tgaccacaat ataccagtaa ttaaattgaa taaaacattt
    15481 tccctatata caatctcttt agaaaaatac ttgacaataa tatatgaagt tatcaacata
    15541 ccaacagatt gaggtaatat aattctatat ccttcaatta aaaatatttg attagttaca
    15601 acatataatg ataaaaatag agatgataat aatacaactc caacacattt taacatattt
    15661 ttatctgtag attttttagt ttgataattt gtgagaagta taccaagtat tatacataat
    15721 attgataaag aaccaatcag taacatttta aaactggtcc attcattaaa caagattaca
    15781 gctaataatg tcgtaaaagt taattgtgaa ccatttgaaa ttggcattac tttagataca
    15841 ctagcaattt gaattgcttt aaactgcatt aattgtccca aactccagaa tatgccagaa
    15901 atcatactta tacaaaatga aaaaaatgta atttcaggat gtataaccag agttattata
    15961 gtggaaaata taaacgcact tatggatgta cctaaaagct gttcatgagg agaacttttc
    16021 tttagatttg caactatggg catcaatccc catcccatta caggaagtaa agcaataatt
    16081 attgtcagca ttaaactatt tcctttcata ttaaatttag acagctttta atttatcatc
    16141 taaaattaaa gtgttcaata tataaaaatt accgtattta atcaggaaat attagtagtt
    16201 ttttagaaaa acattttcca ttaaaataaa gacaaaggga aggagtaaaa ttgaaaatgt
    16261 taactgatat gattcaaaat cgtgaaatta aaataataaa gtttttatta aaagaaggtc
    16321 atacaactgt aaaagcaata gcagatgatt tagatgtttc agaaaaaaca gtttcaaaat
    16381 ctcttaaaga agtagaagca gtgcttaaaa agataggtct ttctttaata agaaaaccta
    16441 agataggtgt ttatattgat ggagatttaa aaaaaatact tccttaccta gataataaag
    16501 gaagtcaaat tcctacaacc agagaggaga gagttatcta tatatattca gtacttttaa
    16561 agagtaatga ttatattact atacaacaac tttctgatga actatatata agtcgtggaa
    16621 ctattgaaag ggatttagca gaagttgaaa aactgctaaa aaacgaaggg atttccatat
    16681 ataagaaacc tagtaaggga ataaagttaa acataagtga aagggataaa agacaactta
    16741 ctgctaagtt tatacataaa ttttggagta gaaactggta tattaagcaa gagcaagaaa
    16801 gcttttatca agcatttgaa aagatacagg cagatgtaaa tggtattttt tcggaagatg
    16861 atttatcaat aattattgat attcttagga atttcagcag agaaagaaaa tttgagttct
    16921 ctgattatga atttcagtca ttagttattc atttggcaat agctgtagag agaattagaa
    16981 aaggcgaata tatagaagaa agtttgtata ttggtaatat agaaaataat caaatgtcaa
    17041 ataccaatta tttagcaaaa caattagaag aaaaattttc aatattatta ccaaaatctg
    17101 aaattggata tataaattta catttagtag cggctgacca acatagagat actaatgaac
    17161 taaaaaatac ttcagctaat ccttgtgaga caagtacaaa taatatatca aatcttcggg
    17221 aaattataaa aaatacattg tatgagacag cttatgacaa ggatttaatt gatggattga
    17281 cttcacatgt acattcatca ataaatagac tgaaatatgg acttagtatt aaaaatccat
    17341 atgtaaatac aatcaaacaa aacttttctt tatcatttga gcaagcttta gatttaaaga
    17401 aagtaattga atttatatat gatattagga taaatgatga tgaatgtgct tatatagcat
    17461 tacattttga agcttttaga gaaagaatga aagaacttcc acaaaatatt agagtaattc
    17521 tagtatgcag tacaggatta ggttcatcta ggttattgtc tgcaagaata aaaaaatact
    17581 ttccaatgat aaagattgaa aaagtacttt ccgtacaaga attagtatcc agtaaaattg
    17641 atgcagattt agtaataagt actatttatt tagagttaga aacaattcca accatagtag
    17701 ttagtcctat tttaaatgaa agtgatataa gaaccttgga aagaaatata caaaatgttt
    17761 caagttgtac ttctaagaag tataaatctt tcagaaattt aatctttgaa gaaaatatat
    17821 tgttgaatat tgaagcttca aattatgaag atgcaattaa tcatataaca gataacctaa
    17881 taaaaaaagg ttttgcaaaa gaaggtatag ctaaaagtgc aattgagaga gaaaatttat
    17941 cttacacgtc tttccagtca atagctacac ctcatgctaa tcctagttat attaaaaaat
    18001 ctaatatatc tgttgcaacg ttaaaaaatc ctattacatg gggaaatgaa aaggtggaag
    18061 ttattttctt tatttcatta gaaaatgaca aaaacctaga gcttgatgaa atatatgaag
    18121 ttttttatga cttcattgac aataaaaaaa atataaatga catattaagt gcaacttcca
    18181 caaaggaagt gtacgatttg ctagtggagg agagtatata gtgaaaatat cagatgtatt
    18241 gaaaaaagag caaattgttt ttaatcttga tacaaataca aaggaagaaa caataaaaaa
    18301 attaagtagt atatttgttg aaaatgggat tgtggacaat gaagaagaat atgttaagtc
    18361 tgttttggaa agagaagaac attcaactac aggtattggt aatggtattg ctattcctca
    18421 tgggaaaagt aatgctgtca aaaaatcttc tataatattt gcaaagacta agcataagat
    18481 tgaatgggat gctttagatg aaaaaccagt agatagtatt ttcttattgg ctataagcaa
    18541 tattgataag gatagcaatc atcttgtact attatctaaa ttagcaacta aacttatgga
    18601 tgatgacaat gtagatgcac taaaattagc caattcagaa caagaaataa tcaatatatt
    18661 tagtgaagaa ggagagatgt agaaatgaaa agaaaaatta tagcagttac agcatgtgca
    18721 acaggagttg cacatacata tatggcagca caagcattaa agaaagcttc aaaaaagatg
    18781 ggtcacctta taaaagttga aacacaagga gctacaggaa tcgataatga gttaactaca
    18841 aaggatgcac aaattgcaga agtagtaata tttgcagtag atactaaagt cagaaatgct
    18901 gaacgttttg agggaaaaga aatactagaa gtaccagtta atgcacctat aaaggatgca
    18961 gagaaagtaa taaatgatgc attaaagtta attgacacta aataaatgga gggaaatgta
    19021 atgttgaaaa agatagtctc tgagttaaaa aagcatgtct taactggaat ctcatatatg
    19081 attccattag taattgcagg tgctatgata atggcgatat ctcgtgtagg tggttctttc
    19141 tataatatac cagatatatg ggatgctaaa tatgcagaaa gtgctagtag tattgttaga
    19201 ttattacatg atttagatgg gtttggaggt actgcgttag gattaatgtt tcctgtaatt
    19261 gctgcattta taggattttc tatagctgat aaattagcta ttgtaccagg tcttgttgga
    19321 ggtatgattg ctaaagatat aggtgcagga tttttaggag ctttggcagt tggtcttata
    19381 gcaggatata catgtttgtt tattaaaaat catgttaaat taccaaaatc agcagcttca
    19441 atagtaccaa tatttatagt accagtattt gggacattaa tcactgttgt attaatcaat
    19501 tatgtgatag gtataccttt tgccacatta aatactggat tagaaaattg gttaaatgga
    19561 ttatctggta caaatcagat actaatggca gctattatag gggctatgat ggcagttgac
    19621 ttaggtggac cagttaataa agcagcttta acaacatcac ttgcattatt aacaagtgga
    19681 atttatgcgc ctaacactgc tgcaatggta ggaatagtta taccaccact aggattggga
    19741 cttgctacta tactagcaaa acaaaaatat aataaacagt tacgtgaagc tgggaaatca
    19801 tctcttataa tgggtttaat tggagtaagt gaaggagcaa ttccttttgc agtagaatct
    19861 ccattaaaag taataccttc atgtgtaatt ggaacagcaa ttgcttcagc tatggcagtt
    19921 ggtttaggtt cagtaaatgc aactccaatt agtggatttt atggatggtt tacagtagag
    19981 aattggccaa tgtatgtgtt atcaatagca gttggaacag taattgtagc tggattagtt
    20041 atagtattgc gtggaaatcc agtgattgag gatgatgaat ttgaagatga tgattttgat
    20101 gaagcagagt gggaatctta aaatttaata actatttaag acgtgttata agctatattc
    20161 aatatgaatc ttatactaaa taaagtgtta aatattcagt ttagacttaa atataaaaga
    20221 taaagaacag aggagaataa atgataaaag cacatattgt taatcataca cactgggata
    20281 gagaatggta ttttacttct ggagatgcat tagtacttag tgaacaacta tttacagatg
    20341 taattgatga attagaacgt aatccagatg taagttttgt acttgatgga caactttcta
    20401 ttttggatga ttatgtacaa ttacacaaag aaaaaataga aatcattaaa aagttaataa
    20461 aagaagatag actacatatt ggaccatggt ttactcaaac tgatgcattc tttgctagag
    20521 gagagtctat tttaagaaac ttaatgattg gaatttttga aagtaaaaag tatggtaagt
    20581 atatgaaaat tgggtatttg ccagatacat ttggatttaa tgcacagatg cctatactat
    20641 taaagcatgt aggtcttgat aatatattct tttggagagg tatacatctt ggtaaacagg
    20701 ttcaatcacc atattttaag tggaaaagct taaatggaga aagttatata tatgcagtaa
    20761 atatgccaca tggatatgga actggtatgc ttttagagcc ttcattaaag tatgttaatg
    20821 gacgcttaga cccagctatt gattttatta aatcatatac tgatgtagat gaggtgttaa
    20881 taccttctgg gaatgaccag ttaaatataa taggtgattt caaaaataaa attaaagcga
    20941 ttaatgatat cggaaagtat tcatatataa cgagttcata tcaagagttt ttaaaatata
    21001 taaagtccat agaatcacta gaaagctata gaggtgaatt tagagaacct gtattagcaa
    21061 gaatacataa atcaattggt tctagtagaa tggatataaa attagcatgt gataaactag
    21121 aaaacaagct gattaaaaga atagagccat tattagtaat tgctaaaaag agcaaaattg
    21181 aaataagcaa tcagttactt ataaatacat ggaaaaaact tttggaagga caagcacacg
    21241 atagtttagc tggatgtgta actgatactg taacagatga tattcttcac cgtataagag
    21301 aagcaaatga aatatgtgac agtattgaaa atactattgt aaaaaagatt tcagaagggc
    21361 ttaaattatc taaaaatgat attttagtat ttaatacaga agctaagcgt tttaatggat
    21421 ataaagagat acaagttgta agtgatagta aaaatattta ttttaaagat aatttagatg
    21481 ctactataat tgaagaaact tatgtaaaac cgagagaaaa tgtattagaa gaaacacctg
    21541 ctggtaatat atttattgaa gaaccaggat attatatatt aaaagtaaga ataaatgtac
    21601 agcttcctgc acttggttat aaagttgtta gttttgaatt aagtgataaa gaaatggtgt
    21661 cacttgataa atctaatgac acttttatat ctaatgataa ttataagata atatatgaag
    21721 atggaagctt aaatttacaa cttaaagatg gaacttacat atcaaacttt ttaacattaa
    21781 aagatagtgg taatgcaggt gatacctatg acttttctcc actaaaaaat gatgagaata
    21841 taaaactttc gtttgataaa gtgtatacag aaaaagcttt aggatatgaa aaaatggtgg
    21901 ttaaaggtac tactttacta ccacttacat tagaagatag aaaaaacaaa tatcttaatg
    21961 gtaaattaaa tgtaaaagta agtattgtct tatctaaaga aaacccattg atggatgtaa
    22021 aactttgtgt tgataacacg atatataatc atagactacg tgttcatata aaaactgata
    22081 taaaagataa taaaaacata gcatcattgc catttggata tataacaaga aaaaatggag
    22141 ttttagacaa ctgggaagat atttacagtg aaatgcctat agatttagaa cctttggaaa
    22201 gtaatattac gcttacaaac caaaatagaa gttgtactgt atttactaga ggaataaaag
    22261 agtatcaaca tattgaagat gaaattgcat tgaccttact tgctactaca gatgaactag
    22321 gaaagcctga tttattatat agaccaggac gtgcttctgg tgatacaact aaaaaaggtc
    22381 atataagaat taaaacagat aaagctcaaa tgcttaagga attagaattt tcatttgcaa
    22441 tatatatgga ttctaaatca tttgatgaat tggaaattgc gaatttaacc cacaattatc
    22501 taagagaatg tgtaaattat caattacagg attacaattt ctttttatat cgtatagata
    22561 ataagattca aaaatcaatt gtcaataaaa ctgtaagtag agaattagaa ataatatctt
    22621 taccagaaaa ctatcttata tcagcatgtt atccttctta ttacagtaaa gataaattta
    22681 taataagagt ggaaaatcca agtagtaata gaatgatatt ggatgagcaa atatttaaaa
    22741 atagaaatgg gaaaattgta aatgcaatag aagatgtaga agaggaacag gtatatgaaa
    22801 tagcaccttt tgacgttatt tcaatattat tggatttata agtgtaaaag taagtttatt
    22861 gtttaaagtc tgacagatat taatctgcca gactttttaa tttgtataaa tttgggtaaa
    22921 tattaatgaa tggttttagt atttaagtat gaatttagta tttaatatag aatttattga
    22981 agtagaataa ttagtttaac aggataagca gtttaaat
//
LOCUS       DAFAZV010000060        22184 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFAZV010000060 DAFAZV010000000
VERSION     DAFAZV010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 22184)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22184)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22184
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.060"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..237
                     /gene="tuf"
                     /locus_tag="KOU88_003353"
     CDS             <1..237
                     /gene="tuf"
                     /locus_tag="KOU88_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452162.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBK3213205.1"
                     /translation="GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTME
                     VDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
     gene            609..920
                     /gene="rpsJ"
                     /locus_tag="KOU88_003354"
     CDS             609..920
                     /gene="rpsJ"
                     /locus_tag="KOU88_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBK3213206.1"
                     /translation="MAKNEKIRIRLKSYDHKLLDFSAGKIVETAKKAGSQVSGPVPLP
                     TEKQVVTILRAVHKYKDSREQFEIRTHKRLIDIANPTPKTVDSLMRLDLPAGVDIEIK
                     L"
     gene            1012..1641
                     /gene="rplC"
                     /locus_tag="KOU88_003355"
     CDS             1012..1641
                     /gene="rplC"
                     /locus_tag="KOU88_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBK3213207.1"
                     /translation="MKGILGKKVGMTQIFTDKGVVIPVTAVEAGPMVVTQIKTVDKDG
                     YNAIQIGFEDAKEKALNKPKKGHLAAANVLKKHLKEFRVDSVEGYTVGQEIKADVFEA
                     GAKIDVTGISKGKGFQGPIKRHGQSRGPETHGSRYHRRPGSMGACSYPGRVFKNKKLA
                     GHMGSVKVTVQNLEVVKVDADKNLILVKGAIPGAKGSVVTIKEAIKVSK"
     gene            1671..2294
                     /gene="rplD"
                     /locus_tag="KOU88_003356"
     CDS             1671..2294
                     /gene="rplD"
                     /locus_tag="KOU88_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001127258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBK3213208.1"
                     /translation="MPKLNVLNVSGQNVGEIELSDSIFGVEVNGHVLYEVVKNQLANK
                     RQGTQSAKTRAEVRGGGRKPWKQKGTGRARQGSTRSVQWVGGGVAFAPKPRSYKYTLP
                     KKVRRLAMKSALSSKVQNSEVIVLDALNMDAPKTKEFAQILNNINAAKKALVVIADKN
                     DNVIKSARNIEGVQTALVNTMNVYDILKYDSFIITTDAVKKVEEVYA"
     gene            2294..2584
                     /gene="rplW"
                     /locus_tag="KOU88_003357"
     CDS             2294..2584
                     /gene="rplW"
                     /locus_tag="KOU88_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBK3213209.1"
                     /translation="MTNPHDVIIRPVVTEHSMAEMGEKKYTFVVAKDANKTEIKKAVE
                     KVFGVSVDKVNTLNYDGKVKRMGRTQGRTSSFKKAVVKLTADSKEIEFFQGM"
     gene            2614..3444
                     /gene="rplB"
                     /locus_tag="KOU88_003358"
     CDS             2614..3444
                     /gene="rplB"
                     /locus_tag="KOU88_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBK3213210.1"
                     /translation="MAIKKFRPTSPALRQMTVLVSDEITCNQPEKSLLVNLKKNAGRN
                     VHGRITVRHRGGGQKRKYRIIDFKRDKDGIPAKVATIEYDPNRTANIALLNYADGEKR
                     YILAPVGINVGDTILSGLGADIKPGNCLALKDMPVGTIIHNIELKPGKGAQLVRSAGV
                     SAQLMAKEGKNALLRLPSGEMRLVSINCKATIGQVGNIEHGNVVIGKAGRKRHMGIRP
                     TVRGSVMNPNDHPHGGGEGRSPIGRPSPVTPWGKPALGYKTRKKNKASNKLIVSRRTK
                     "
     gene            3479..3760
                     /gene="rpsS"
                     /locus_tag="KOU88_003359"
     CDS             3479..3760
                     /gene="rpsS"
                     /locus_tag="KOU88_003359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003454422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBK3213211.1"
                     /translation="MSRSTKKGPFVHARLLKKIEAMNASGNKEVIKTWSRSSTVFPQM
                     VENTIAVHDGRKHVPVYITEDMVGHKLGEFVPTRTFKGHKDDEKSNKRK"
     gene            3792..4127
                     /gene="rplV"
                     /locus_tag="KOU88_003360"
     CDS             3792..4127
                     /gene="rplV"
                     /locus_tag="KOU88_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBK3213212.1"
                     /translation="MEAKATAKYVRVSPRKAGQICDLVRGKNVDEALAILKFTPRGAA
                     SIIAKVVKSAKANAENNHEMDTEKLYIASIVANQGPTMKRFMPRAMGRATTIRKRTSH
                     IEVVVKEKK"
     gene            4150..4965
                     /gene="rpsC"
                     /locus_tag="KOU88_003361"
     CDS             4150..4965
                     /gene="rpsC"
                     /locus_tag="KOU88_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBK3213213.1"
                     /translation="MGQKVNPHGLRVGVIKDWDSRWFATDKKEFGNLLLEDHNIRKFL
                     KKRLYSAGVAKIEIERSANKIKMDLHVAKPGVVIGRAGAGIEALKAELEKMTKKTIIV
                     NIVEVRSTDKNAQLVAENIALAIERRVAFRRAMKQAIQRAMKSGAKGIKVSASGRLGG
                     AEMARTEGYSEGNVPLQTLRADIDYGFAEADTTYGKIGIKVWICNGEVLPTRDGVNPR
                     EESRKSDRRDNKRDNRRNDRRGNDRRGNDNRGNYRGQRPQGGSRPQRTENKGN"
     gene            5001..5432
                     /gene="rplP"
                     /locus_tag="KOU88_003362"
     CDS             5001..5432
                     /gene="rplP"
                     /locus_tag="KOU88_003362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBK3213214.1"
                     /translation="MLMPKRVKRRRVHRGSMAGQAHKGNKVTYGEFGLVALEASWITS
                     NQIEAARIAMTRYIKRGGKVWIKIFPHKPVTRKPAETRMGAGKGSPEYWVAVVKPGRV
                     MFELAGVSEDKAREAMRLAAHKLPIKCKFVKKEDLEVKGGE"
     gene            5434..5637
                     /gene="rpmC"
                     /locus_tag="KOU88_003363"
     CDS             5434..5637
                     /gene="rpmC"
                     /locus_tag="KOU88_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBK3213215.1"
                     /translation="MKAKELRDLTSEELMNKLNDFKSELFSLRFQLATGQLENTARIK
                     FVKKDIAKVKTVLAERKLYETRA"
     gene            5661..5915
                     /gene="rpsQ"
                     /locus_tag="KOU88_003364"
     CDS             5661..5915
                     /gene="rpsQ"
                     /locus_tag="KOU88_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBK3213216.1"
                     /translation="MERGRRKVRIGRVVSDKMDKTIVVAVEEFVRHPLYNKRVKRTKK
                     FKAHDEKNICNIGDRVKIMETRPLSKDKRFRLVEVVEKVK"
     gene            5941..6309
                     /gene="rplN"
                     /locus_tag="KOU88_003365"
     CDS             5941..6309
                     /gene="rplN"
                     /locus_tag="KOU88_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007885948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBK3213217.1"
                     /translation="MIQQESRLRVADNSGAKELLCIRVLGGSKRRYGNIGDVIVATVK
                     SATPGGVVKKGKVVKAVIVRSKQGVRRNDGSYISFDENAAVIIKDDKTPVGTRIFGPV
                     ARELRDNEFMKIVSLAPEVL"
     gene            6333..6638
                     /gene="rplX"
                     /locus_tag="KOU88_003366"
     CDS             6333..6638
                     /gene="rplX"
                     /locus_tag="KOU88_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBK3213218.1"
                     /translation="MRVKKGDTVVVIAGKDKGKKGSVLKVYPKTSKVLVEGVNVITKH
                     QKPSAMNQQGGIINKEAPIHISNVMPFDPETGKGVRVRYEVKDGNKVRVSAKSGKEL"
     gene            6668..7210
                     /gene="rplE"
                     /locus_tag="KOU88_003367"
     CDS             6668..7210
                     /gene="rplE"
                     /locus_tag="KOU88_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBK3213219.1"
                     /translation="MASRLQEKYMKEVAPALMEKFGYKNVMEIPKLNKIVINMGIGDA
                     RENPKGLEKGVEELEMISGQKPVITKARKSVANFKLREGMPIGTKVTLRADKMFYFMD
                     KLVSVSLPRVRDFRGVNPNAFDGRGNYALGVKEQLIFPEIEYDKIDKVRGMDIIFVTT
                     AKTDEEARELLKLLGMPFSK"
     gene            7228..7413
                     /locus_tag="KOU88_003368"
     CDS             7228..7413
                     /locus_tag="KOU88_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBK3213220.1"
                     /translation="MARKAMVVKQQRKQKYATREYTRCTICGRPHSVLKKFGICRICF
                     RELAYKGQIPGVRKASW"
     gene            7446..7844
                     /gene="rpsH"
                     /locus_tag="KOU88_003369"
     CDS             7446..7844
                     /gene="rpsH"
                     /locus_tag="KOU88_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBK3213221.1"
                     /translation="MTMTDPIADMLTRIRNANVVKHETVDVPASNMKKELARILLEEG
                     FIRGYDVIEDGKQGIIRIQLKYGQEGERVITGLKKISKPGMRVYAANHEIPKVLNGLG
                     ISVISTSKGILTDKQARKENVGGEVICYVW"
     gene            7875..8417
                     /gene="rplF"
                     /locus_tag="KOU88_003370"
     CDS             7875..8417
                     /gene="rplF"
                     /locus_tag="KOU88_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBK3213222.1"
                     /translation="MSRIGVKPIIIPAGVEVTIAEGNLVTVKGPKGTLTKQLSAELNI
                     KKEENTIMVERPTDNKKHRSLHGLTRTLLDNMVVGVNTGFEKKLELKGVGYRAQKQGK
                     KLVMNLGFSHPVEMEDPEGITVEAPNQTELIVKGIDKQLVGNYAAKIRAWRKPEPYKG
                     KGIKYVDEVIRRKEGKTGKK"
     gene            8453..8821
                     /gene="rplR"
                     /locus_tag="KOU88_003371"
     CDS             8453..8821
                     /gene="rplR"
                     /locus_tag="KOU88_003371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBK3213223.1"
                     /translation="MLKKADKNANRLQRHKRVRRKISGTSQRPRLCVFRSANNIYAQI
                     IDDTKRVTLVAASSLEAEVKSAVNHTGNKEAAKKVGELVAKKAVEKGITEVVFDRGGY
                     LYHGRIQELAEGAREAGLKF"
     gene            8842..9351
                     /gene="rpsE"
                     /locus_tag="KOU88_003372"
     CDS             8842..9351
                     /gene="rpsE"
                     /locus_tag="KOU88_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011109776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBK3213224.1"
                     /translation="MLRRKPIDAGQLDLQEKVVEVRRVTKVVKGGRNFRFAALVVVGD
                     ENGHVGIGAGKAMEVPDAIKKAVEDAKKNLIVVPIVGTTIPHEVRGHFGAGNILIMPA
                     VEGTGVIAGGPARAVLELAGLKDVRAKSLGSNNPRNMVNATIEGLNSLKTVEDIAKLR
                     GKKVEELLG"
     gene            9366..9551
                     /gene="rpmD"
                     /locus_tag="KOU88_003373"
     CDS             9366..9551
                     /gene="rpmD"
                     /locus_tag="KOU88_003373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBK3213225.1"
                     /translation="MAKLQIKLVRSVIGTTPNQKKNVEALGLRKREQVVVKEDNAQTR
                     GMINKVSHLLEVTEIAE"
     gene            9584..10027
                     /gene="rplO"
                     /locus_tag="KOU88_003374"
     CDS             9584..10027
                     /gene="rplO"
                     /locus_tag="KOU88_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBK3213226.1"
                     /translation="MKLHELKPAEGAVRAKRRLGRGTATGQGKTAGRGQKGQWSRSGG
                     GVRVGFEGGQMPLARRLPKRGFNNIFKKVYTEVNVEVLNRFENGTEITAELLKSTKTI
                     SKIGKDGIKILGEGNLEKALTVKAAKFTASAQEKIEKAGGKAELV"
     gene            10071..11339
                     /gene="secY"
                     /locus_tag="KOU88_003375"
     CDS             10071..11339
                     /gene="secY"
                     /locus_tag="KOU88_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBK3213227.1"
                     /translation="MLSKLKQAWKIKAVRKKVMYTLMMIVIFRIGTTIPVPGIDTSII
                     QKMVGGNSLLSLYNMFTGGAFSNFSLFALGISPYITASIIIQLLTVGFESLAELQKSG
                     EEGKKKINKYTKYTALALAVVQALGITLGIVRSALISNSVFFITTVVITLVSASMLVM
                     WIGDKITEKGIGNGSSVIIFAGIISRIPTDVIKISQQVKSDEVAPWVIVILAVVILLT
                     VTGVTFIQEATRKIPVQYAKRVVGRKMYGGQSSHIPMKVNQSGVMPIIFASSLLAFPQ
                     TIAMFMGPNAQAFVQKYLSMATEQGFWTYRSIEILLIIFFSYFYTTVSFNTEDISKNM
                     KNNGGFIPGIRPGEPTMDYLNRILTRLTLAGATFLAIIAMVPALTTHYMKVNMSLAGT
                     SLLIVVGVALELKRQLESNLVMRSYQGFLK"
     gene            11356..12006
                     /locus_tag="KOU88_003376"
     CDS             11356..12006
                     /locus_tag="KOU88_003376"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBK3213228.1"
                     /translation="MRIILLGPPGAGKGTQAAGIVEKYNIPHISTGDIFRKNIKEGTE
                     LGKKAKEYMDQGLLVPDELTVGLVTDRISQEDCKNGFMLDGFPRNVAQGEHLDIFLKN
                     AGISLDKVVNIEVDKSILVSRAVGRRICKSCGATYHVEFNPPKVEGVCDVCQGELYQR
                     ADDNEETVSKRIQVYLDETKPLVDYYSKQGIIADIKGDQAIDKVFEDIVAALGSGK"
     gene            12007..12753
                     /gene="map"
                     /locus_tag="KOU88_003377"
     CDS             12007..12753
                     /gene="map"
                     /locus_tag="KOU88_003377"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBK3213229.1"
                     /translation="MIILKSKKEIELLREAGKIVADTHEVLRKAISPGISTLELDKIA
                     EENIRKYNAEPSFKGYGGFPGSICASINREVVHGIPGETILQEGDIVSLDIGAYYKGY
                     HGDSAKTHGVGMISEEDRKLIEVTRESFYEGIKFAKLGYRLSDISHAVQTHVEKHGFS
                     VVRDLVGHGVGANLHEDPQVPNYGLPGKGPRLREGMVIAIEPMVNAGRYHVKTLSDGW
                     TTVTIDGKKSAHYEHTIAITEHEPLILTKL"
     gene            12775..13044
                     /locus_tag="KOU88_003378"
     CDS             12775..13044
                     /locus_tag="KOU88_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KOW domain-containing protein"
                     /protein_id="HBK3213230.1"
                     /translation="MLSDNLSIGQVVKVSLGRDKGNLFFVVKIINNEYVLIADGKKRK
                     LDKPKLKKVKHLKKYNFINDEVRKRVVSGQEITDSFLRAELTKLN"
     gene            13082..13300
                     /gene="infA"
                     /locus_tag="KOU88_003379"
     CDS             13082..13300
                     /gene="infA"
                     /locus_tag="KOU88_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBK3213231.1"
                     /translation="MAKKDVIELEGTVSEALPNAMFKVKLENGHEILCHISGKLRMNF
                     IRILEGDKVNVELSPYDLTRGRITWRKK"
     gene            13336..13449
                     /gene="rpmJ"
                     /locus_tag="KOU88_003380"
     CDS             13336..13449
                     /gene="rpmJ"
                     /locus_tag="KOU88_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBK3213232.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQKQG"
     gene            13602..13973
                     /gene="rpsM"
                     /locus_tag="KOU88_003381"
     CDS             13602..13973
                     /gene="rpsM"
                     /locus_tag="KOU88_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005810116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBK3213233.1"
                     /translation="MARIAGVDLPREKRAEIGLTYIYGIGKATANEILAKAEINPDTR
                     IKDLSEDQVNELRKVIDDDFLVEGDLRREIALNIKRLRDIKCYRGIRHAKGLPLRGQR
                     TKTNARTRKGPRKTVSRKKKK"
     gene            14009..14407
                     /gene="rpsK"
                     /locus_tag="KOU88_003382"
     CDS             14009..14407
                     /gene="rpsK"
                     /locus_tag="KOU88_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBK3213234.1"
                     /translation="MAKPKKKVTRIRRRERKNIERGHAHIQSTFNNTIITLTDVHGNA
                     ISWASSGQLGFKGSRKSTPFASQMAAETAAKAAMEHGLKSVEVFVKGPGSGREAAIRA
                     LQATGLEVTMIKDVTPIPHNGCRPPKRRRV"
     gene            14439..15062
                     /gene="rpsD"
                     /locus_tag="KOU88_003383"
     CDS             14439..15062
                     /gene="rpsD"
                     /locus_tag="KOU88_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBK3213235.1"
                     /translation="MARYTGASCRQCRREGMKLFLKGDRCYTDKCAIVKRNYAPGQHG
                     QGRKKVSNYGLQLREKQKVKRIYGVLETQFRNLYERAENMPGKAGENLLSLLERRLDN
                     VVYRMGLASSRKEARQLVTHGHFTLNGNKVDIPSLIVKVGDVIEVKEKSRSSAKFKNL
                     VEVNSRIAPKWLEANVEGMTAKVVGVPTREDIDLEIAEHLIIELYSK"
     gene            15140..16087
                     /locus_tag="KOU88_003384"
     CDS             15140..16087
                     /locus_tag="KOU88_003384"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBK3213236.1"
                     /translation="MIEIEKPKVDIVELSEDYRYGKFVIEPLERGYGITIGNALRRIL
                     LSSLPGVAVNAIKIDGVLHEFSTIPGVKEDVTEIILTLKELSATIDGEGSRTLKIEAQ
                     GPCSITGADIICPPDVEILSKDLAIATLDDNAKLNMEIFVDKGRGYVSAEENKTENVP
                     IGVLPVDSIYTPVEKVSYHVENTRVGQKTDYDKLVLEVWTNGSINPQEGISLAAKVLV
                     EHLNLFIDLTEHVSSVEIMVEKEEDQKEKVLEMTIEELDLSVRSYNCLKRAGINTVEE
                     LANKSEDDMMKVRNLGKKSLEEVIQKLEELGLGLKPSEE"
     gene            16108..16449
                     /gene="rplQ"
                     /locus_tag="KOU88_003385"
     CDS             16108..16449
                     /gene="rplQ"
                     /locus_tag="KOU88_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003357477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBK3213237.1"
                     /translation="MAKYRKLGRETAHRNLMLRNLVTCLLRSGRIETTVTRAKETRRM
                     AEKMITLAKRGDLHARRQVLAYVMDETVVNNLFTDLAPKYAERNGGYTRIIKIGPRKG
                     DAAEMAFIELV"
     gene            16569..17402
                     /locus_tag="KOU88_003386"
     CDS             16569..17402
                     /locus_tag="KOU88_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBK3213238.1"
                     /translation="MDNIVKVNNISFEYITDEAKLKAIDNLSLDVKKGEFVAIIGHNG
                     SGKSTLSKNLNAILMPTEGNILIDDMDTKEEERLWDIRQTAGMVFQNPDNQIVATIVE
                     EDVAFGPENLGIEPKEIRRIVEESLKSVGMYDLRDRQPHLLSGGQKQRVAIAGIIAMR
                     PKCIIFDEATAMLDPSGRKEVMKTIKRLNKEENITVIHITHFMEEAVEADRVVVMEKG
                     KKILEGTPREVFSKIKMLKEIGLDVPCMTELSSLLIEEGINISSDILTVDEMVMELCQ
                     L"
     gene            17390..18256
                     /locus_tag="KOU88_003387"
     CDS             17390..18256
                     /locus_tag="KOU88_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HBK3213239.1"
                     /translation="MSIIVKNLTHIYNEGMPFASKALDDVSFEIKDRDFVGLIGHTGS
                     GKSTLIQHLNGLLKPSSGEIFINDFNITDKNLNLTEIRKRVGVVFQYPEYQLFEETID
                     KDIAFGPSNLGLEESEIHNRVKASMEAVGLDYEGFKDKSPFELSGGQKRRVAIAGVIA
                     MNPEVLILDEPTAGLDPGGRDEIFNLIKDLHEKKNMTIILSSHSMDDMAKLAKTLIVM
                     NHGSVEFMGTPREVFKSNASKLKDIGLDIPQVLELALKLREKGFDISEDILTLEEAKQ
                     EILKVVRGRGLC"
     gene            18250..19053
                     /locus_tag="KOU88_003388"
     CDS             18250..19053
                     /locus_tag="KOU88_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBK3213240.1"
                     /translation="MLKDITIGQYYPTSSAIHKLDPRIKLVATIVFMVSIFVVNKFWP
                     YIVVLLCLLAMIKLANIPVKYIVKGVKPLKWIILFTFLINIFFLPGDEIWSFGFLAIT
                     KQGLRQAIFMAIRLIFLVVGTSLLTLTTSPIELTDGIERLLNPFKKIGLPVHELAMMM
                     TIALRFIPTLLDETDKIMKAQMSRGADFESKNLINRAKNLVPLLVPLFVSAFRRADEL
                     AMAMEARCYRGGHNRTKMRESVISRRDYMACVFQVVYLGAIIATRFIAI"
     gene            19085..19816
                     /gene="truA"
                     /locus_tag="KOU88_003389"
     CDS             19085..19816
                     /gene="truA"
                     /locus_tag="KOU88_003389"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003514691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBK3213241.1"
                     /translation="MRNIKIKIQYNGKNYCGWQKQPDSLGIQGTIERAIYDITKEETS
                     LIGSGRTDSGVHAIGQIANFKINSGISIESIPMALNAKLPKDISVIEACEVNDDFHSR
                     YSAKGKTYKYLVYNSKFRNPILSEISYQVKYELDFDKMCSEAKSLLGTHDFKGFMSSG
                     SSVKDTVRTIYDIDISKKDDLITFEISGNGFLYNMVRIIVGTLVDMGRGRINEPFLDI
                     IQSKTRSRCGHTAPAQGLFLKKVHY"
     gene            19936..20367
                     /gene="rplM"
                     /locus_tag="KOU88_003390"
     CDS             19936..20367
                     /gene="rplM"
                     /locus_tag="KOU88_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBK3213242.1"
                     /translation="MKSYIAKPADVQRKWYLVDAEGKTLGRLATEIATVLRGKHKPTF
                     TPHVDGGDFVVVVNAEKIVLSGKKLDQKYYRYHTGYVGGLKEISYRDMMDKKPEEVIS
                     HAVSGMLPKNKLRSRMMTRLRVFAGAEHTHAAQNPEVLNFK"
     gene            20396..20788
                     /gene="rpsI"
                     /locus_tag="KOU88_003391"
     CDS             20396..20788
                     /gene="rpsI"
                     /locus_tag="KOU88_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003515879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBK3213243.1"
                     /translation="MANVQYYGTGRRKSSVARVRLVAGEGNILVNGRALENYFNYETL
                     IRDVKQPLVLTGNENKYDVIVKVEGGGFTGQAGAIRHGISRALLKADLDLRPALKKEG
                     FLTRDARMKERKKYGLKAARRAPQFSKR"
     gene            21247..21999
                     /gene="cwlD"
                     /locus_tag="KOU88_003392"
     CDS             21247..21999
                     /gene="cwlD"
                     /locus_tag="KOU88_003392"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase CwlD"
                     /protein_id="HBK3213244.1"
                     /translation="MEYYSVFISIHIQGDVVRKYIKHIIFSFAMICLVVVSIFEIKNI
                     SEDVIKYMPVTNKTIILDAGHGGIDPGALNKDKSTSEKDINLAITLKLRELIESSGGL
                     VILTREDDSSLYKEENNKTTRQKYNENLKNRKEIISNSNANMFVSIHLNAFEQSKYYG
                     AQTFYPKDKQDSKELSKCIQEELKRVVDKTNNREVKPRDDIYLLKENNIPSVLIECGF
                     LSNEKECKLLTDETYQEKIAWAIYIGIQKYLS"
BASE COUNT         8913 a         2593 c         4550 g         6128 t
ORIGIN      
        1 ggtggaagac atacaccatt ctttgatgga tatagaccac aattctattt cagaacaaca
       61 gacgtaacag gagcttgtaa gttaccagaa ggaatagaga tggtaatgcc tggagataac
      121 gtaacaatgg aagtagactt aataaactca atagttgtag aagagggatt aagattctca
      181 ataagagaag gtggaagaac agtagcttca ggagttgttg ctacaataat agagtaatcc
      241 tttactaaac taatggattt aatataaaaa aagagggggg taactcctct cttttttgtt
      301 ttttgttgac aagtagcgct aaagcatata tactaaacta gtgccttgag acagattaac
      361 aatcaagttt aaggttatga tgttgtaata gaaaataaaa ttgaaaaaaa cagaaaaaaa
      421 acttgaaaaa atgtaacaga tgatataaaa tataatagtg tgcttgagag attaagaaaa
      481 taataattaa atcctagtga aatacgaact gatatcgatt taaaagttac aacacacccg
      541 gagcagtgta tcggtattgg ttgtacgcaa cttgaaaatt aaacacgtga taaaggaggg
      601 aaaacaaaat ggctaagaat gaaaaaataa gaataagatt aaaatcatat gatcacaaat
      661 tattagattt ttcagcaggt aaaatagttg aaactgctaa aaaggctgga tcacaagttt
      721 caggacctgt gcctctacca acagaaaaac aagttgtaac tatattaaga gctgtacata
      781 agtacaaaga ctctagagaa caatttgaaa taagaactca taaaagacta atcgacatag
      841 ctaatccaac acctaagaca gttgactcat taatgagatt agacttacca gcaggtgtag
      901 atatagaaat aaaattataa aaacccctaa gatattatcc tatagatgat tatcttagaa
      961 tgattactct aaaagatgta atccgctgta agaattatag gaggtgctaa tatgaaagga
     1021 atattaggca aaaaagttgg tatgactcaa atattcactg ataaaggtgt agttatacct
     1081 gtaacagctg ttgaagcagg gcctatggtc gttactcaaa taaaaacagt tgataaagat
     1141 ggatacaatg ctatacaaat aggttttgaa gatgctaaag aaaaagcttt aaacaaacct
     1201 aaaaaaggac atttagctgc tgctaatgtt ttaaagaaac atttaaaaga atttagagta
     1261 gattctgtag aaggatacac agtaggacaa gaaataaaag ctgatgtatt tgaagcaggt
     1321 gcaaaaatag atgttactgg aataagtaaa ggtaagggat tccaaggtcc aataaaaaga
     1381 catggacaaa gtagaggtcc tgaaactcac ggttctagat accacagaag accaggttca
     1441 atgggagctt gttcttaccc aggtagagta tttaaaaaca aaaaattagc tggacatatg
     1501 ggaagcgtaa aggtaacagt tcaaaactta gaggttgtta aagtagatgc tgacaagaac
     1561 cttatattag ttaaaggagc tataccagga gctaaaggtt cagtagtaac tataaaagaa
     1621 gctataaagg tttctaaata atgactaacc tagagaaagg aggaataaca atgccaaaat
     1681 taaatgtact aaatgttagt ggacaaaacg ttggagaaat agaattatca gattctatat
     1741 ttggcgtaga agttaatgga catgttttat acgaagttgt aaaaaatcaa ttagcaaata
     1801 agagacaagg aactcaatct gctaaaacta gagcagaagt tagaggtggc ggaagaaaac
     1861 cttggaaaca aaaaggaaca ggtagagcaa gacaaggttc tacaagatct gtacaatggg
     1921 taggtggagg agttgctttt gcacctaaac caagaagcta caaatataca ttacctaaga
     1981 aggtaagaag attagctatg aagagtgctt tatcttcaaa agttcaaaat agtgaagtta
     2041 tagtattaga tgcattaaac atggatgctc ctaagactaa agaatttgct caaatattaa
     2101 acaatataaa tgctgctaaa aaagctttag tagttatagc tgacaaaaac gataacgtaa
     2161 taaaatcagc tagaaatata gaaggtgttc aaactgcatt agttaatact atgaatgtat
     2221 atgatatatt aaaatacgat tcatttataa taactacaga tgctgttaaa aaagtggagg
     2281 aggtgtacgc ataatgacta atccacatga tgtaataata agaccagttg taactgagca
     2341 cagtatggct gaaatgggtg aaaaaaaata cacttttgtt gtggctaaag atgcgaacaa
     2401 aactgaaata aaaaaagcag tagaaaaagt attcggagtt agtgttgata aagtaaatac
     2461 tttaaactac gatggaaaag ttaaaagaat gggtagaact caaggaagaa catcaagctt
     2521 taagaaagca gtagttaaat taactgctga tagtaaagaa atagaattct tccaaggaat
     2581 gtagtattat aacaaacgaa ggagggaaaa cagatggcta taaaaaagtt tagaccaact
     2641 tctcctgcct taagacaaat gacagtttta gtttctgatg aaataacatg taatcaacca
     2701 gaaaaatctc ttttagttaa cttaaagaaa aatgctggta gaaacgtaca tggtagaata
     2761 actgttcgtc atagaggtgg aggacaaaaa agaaaatata gaataataga ttttaaaaga
     2821 gataaagatg gtatacctgc taaggttgct actatagaat atgatccaaa cagaactgca
     2881 aatatcgcat tattaaacta tgctgatgga gaaaaaagat atatattagc tccagttgga
     2941 attaatgttg gagatactat attatcagga ttaggtgctg atataaaacc aggaaactgt
     3001 ttagcattaa aagatatgcc agttggtact atcattcata atatagaatt aaagccagga
     3061 aaaggagctc aattagttag atctgctgga gtttctgcac aattaatggc taaagaagga
     3121 aaaaatgctt tattaagatt accatcaggt gagatgagat tagtaagcat aaactgtaaa
     3181 gctactatag gtcaagttgg aaatatagag catggtaacg tagttatcgg taaagcaggt
     3241 agaaaaagac atatgggaat aagacctact gtaagaggtt ctgtaatgaa ccctaatgac
     3301 catccacacg gtggagggga aggtagatct ccaataggta gaccatctcc tgttactcca
     3361 tggggtaaac cagctcttgg atacaaaact agaaagaaaa ataaagcttc aaataaacta
     3421 atagtatcaa gaagaactaa gtagtaaatt tatttttgct cggaaaggag gaatataaat
     3481 gtcaagatca actaaaaaag ggccttttgt ccatgcaaga cttttaaaga agatagaagc
     3541 tatgaatgct agtggaaata aagaagttat aaaaacttgg tcaagatctt caactgtatt
     3601 tccacaaatg gtagaaaaca ctatagctgt tcatgatgga agaaaacatg ttccagtata
     3661 tataacagaa gatatggttg gacataaatt aggtgagttc gttcctacta gaactttcaa
     3721 aggacataag gatgacgaaa aatctaataa gagaaaataa ttaaattatg actaagaaag
     3781 gaggaataac aatggaagca aaagctactg ctaaatacgt acgtgtatca ccaagaaaag
     3841 caggccaaat atgtgacctt gttagaggaa agaatgttga tgaagcatta gcaatattaa
     3901 agtttactcc aagaggagca gcttcaataa tagctaaggt tgtaaaatca gctaaagcta
     3961 acgcagaaaa caatcacgaa atggatactg aaaaattata tatagcatca atagttgcta
     4021 atcaaggacc aacaatgaag agattcatgc ctagagctat gggtcgtgca actacaataa
     4081 gaaaaagaac ttctcatata gaggttgttg ttaaagaaaa aaaataatta atagatagga
     4141 gggaaagtaa tgggtcaaaa ggttaatcca cacggcttaa gggtcggtgt tataaaagat
     4201 tgggactcaa gatggttcgc tactgataaa aaagagttcg gaaacttatt attagaagac
     4261 cataatatac gtaaattctt aaagaaaaga ttatactcag ctggagttgc taagatagaa
     4321 atagaaagat cagctaacaa aataaaaatg gacttacacg ttgctaagcc tggtgtagtt
     4381 ataggaagag ctggtgcagg aatcgaagca ttaaaagctg aattagaaaa aatgacaaag
     4441 aaaactataa tagttaatat agtagaagta agaagtacag ataaaaatgc tcaattagta
     4501 gctgaaaata tagctttagc tatagagaga agggttgctt tcagaagagc aatgaaacaa
     4561 gctatacaaa gagcaatgaa atctggtgct aaagggataa aagtttctgc ttcaggaaga
     4621 ttaggtggag ctgaaatggc tagaactgaa ggttatagtg aaggaaatgt gccactacaa
     4681 actttaagag cagatataga ttatggtttc gctgaagctg atacaactta tggaaaaatc
     4741 ggtataaaag tttggatatg taatggtgaa gttttaccaa ctagagacgg tgtaaatcca
     4801 agagaagaaa gcagaaagag cgatagaaga gacaacaaga gagataatag aagaaacgat
     4861 agaagaggaa atgacagaag aggaaatgat aacagaggaa actacagagg acaaagacct
     4921 caaggtggat caagacctca aagaactgaa aacaaaggaa attaataata gttaggttca
     4981 aggaaggagg aaaaatactc atgttaatgc caaaaagagt aaagcgtcgt agagttcata
     5041 gaggaagcat ggctgggcaa gctcataagg gtaataaagt tacttatggt gagtttggat
     5101 tagtagcatt agaagcttct tggataactt ctaatcaaat agaagctgcc agaatcgcga
     5161 tgactagata tataaaaaga gggggaaagg tttggataaa aatattccct cataaaccag
     5221 taacaagaaa accagcagag actcgtatgg gtgcagggaa aggttctcca gaatattggg
     5281 tagctgtagt taagccagga agagttatgt ttgaattagc aggtgtttct gaagataaag
     5341 caagagaagc tatgagactt gctgcacata aattaccaat caaatgtaaa tttgttaaaa
     5401 aagaagattt agaagtaaag ggtggtgaat aggatgaaag ctaaagaatt aagagattta
     5461 acaagcgaag agctaatgaa caaattaaac gacttcaaaa gtgaattatt tagcttaaga
     5521 ttccaattag ctactggtca attagaaaat acagctagaa taaagtttgt taagaaggat
     5581 atagcaaaag ttaaaactgt tcttgctgaa agaaagttat acgaaactag agcttaattt
     5641 ggaaaggagg ctttttaaac atggaaagag gaagaagaaa agttagaata ggccgtgttg
     5701 ttagtgataa gatggataaa acaatagtag tagctgttga agaattcgta cgtcatccac
     5761 tatataataa acgtgttaag agaactaaga aattcaaggc tcatgatgaa aagaatatat
     5821 gtaacatcgg agatagagtt aaaataatgg aaactagacc attatctaaa gataagagat
     5881 tcagactagt tgaagttgtt gagaaagtta agtagttttt gaagaaggag ggattacgat
     5941 atgatacaac aagaatcacg tctaagagtt gctgataact caggagctaa agaactttta
     6001 tgtatacgtg ttctaggcgg aagtaaaaga agatatggta acataggcga cgttatagtt
     6061 gctactgtta aaagtgcaac acctggtgga gttgtaaaaa aaggtaaggt tgttaaagct
     6121 gttatagtaa gaagcaaaca aggcgtaaga cgtaatgacg gaagctatat atcttttgat
     6181 gaaaatgctg ctgttataat aaaggacgat aaaactccag taggaactcg tatattcggg
     6241 cctgttgcta gagagttaag agacaatgaa ttcatgaaaa tagtttctct tgctccagaa
     6301 gtactataat taaggaggtg caataggaca tgatgcgtgt taaaaaaggt gacactgttg
     6361 tagttatagc aggtaaagat aaaggtaaaa aaggttcagt tttaaaggta tatcctaaaa
     6421 ctagcaaagt gttagttgaa ggtgtaaatg taataactaa acatcaaaaa ccaagtgcta
     6481 tgaaccaaca aggtggaata ataaataaag aagccccaat acacatatct aatgtaatgc
     6541 catttgatcc tgaaacagga aaaggcgtta gagtaagata tgaagtaaaa gatgggaaca
     6601 aagtaagagt atcagcaaag agcggaaaag aattataata aatattgctt gaaaggaggg
     6661 accttaaatg gcttctagat tacaagaaaa atacatgaaa gaagttgctc ctgctttaat
     6721 ggagaaattt ggatacaaaa acgtaatgga gatacctaag ttaaataaaa tagttattaa
     6781 catgggtata ggtgacgcta gagaaaatcc aaaaggatta gaaaaaggcg ttgaagaatt
     6841 agaaatgata tcaggacaaa agcctgttat aactaaagct agaaaatctg ttgctaactt
     6901 caaattaaga gaaggaatgc caataggaac aaaagttaca ttaagagctg acaaaatgtt
     6961 ctacttcatg gacaaattag tttcagtttc tttaccaaga gttagagact ttagaggagt
     7021 taaccctaat gcttttgatg gtagaggaaa ttatgcttta ggagttaaag aacaattaat
     7081 attccctgaa atagaatatg ataaaataga taaagtaaga ggaatggata taatatttgt
     7141 tactacagca aaaactgacg aagaagctcg tgaattatta aaattattag gaatgccatt
     7201 ttctaagtaa gcaaaggagg gattcccgtg gctagaaaag cgatggttgt taagcaacaa
     7261 agaaagcaaa agtacgctac tagagaatac actagatgta ctatatgcgg aagaccgcat
     7321 tcagttttga aaaaatttgg tatatgccgt atatgcttta gagaattagc ttataaaggt
     7381 caaatacctg gtgttagaaa agcaagctgg tagaagcttg attagaatgg aaggagggca
     7441 acaaaatgac aatgacagat ccaattgcag atatgcttac tcgtataaga aatgctaatg
     7501 ttgttaagca tgaaactgta gatgttccag cttctaatat gaagaaagaa ttagctagaa
     7561 tcttattaga agaaggtttc ataagaggtt atgatgttat agaagatgga aaacaaggta
     7621 tcataagaat acaattaaag tacggacaag aaggcgaaag agttataaca ggtcttaaga
     7681 aaatatctaa gcctggaatg agagtttacg ctgctaacca tgagatacca aaagtattaa
     7741 acggattagg aatatcagtt atatctactt caaaaggaat attaactgac aagcaagcta
     7801 gaaaagaaaa tgttggtgga gaagtaatct gctacgtttg gtaattaata tgaacaatgt
     7861 aaggaggtgc gaccatgtca agaataggtg ttaagccaat aataatacca gcaggtgttg
     7921 aagttactat agctgaagga aatttagtta cagtaaaagg tccaaaagga actttaacta
     7981 aacaattaag tgctgagtta aacataaaaa aagaagaaaa tacaataatg gttgaaagac
     8041 caactgataa taaaaaacat agatctttac acggactaac tagaacttta ttagataata
     8101 tggttgtagg tgtaaatact ggtttcgaaa agaaattaga attaaaaggt gttggatata
     8161 gagctcaaaa acaaggaaag aaattagtta tgaacttagg tttctctcat ccagttgaga
     8221 tggaagatcc agaaggaata actgttgaag ctccaaacca aacagagtta atagtaaaag
     8281 gtatagacaa gcaattagta gggaattatg ctgctaagat aagagcttgg agaaagccag
     8341 agccatacaa aggtaaaggt ataaaatacg ttgatgaagt aatcagacgt aaagaaggaa
     8401 aaactggtaa aaaataatac caaaacttaa acgctagaaa ggagtgagct aggtgttaaa
     8461 aaaggctgat aaaaatgcta atagacttca aagacataag agagttcgta gaaaaataag
     8521 cggtacttct caaagaccaa gattatgtgt atttagaagt gctaacaata tatatgctca
     8581 aataatagat gacacaaaaa gagtaactct agttgctgca tcttctttag aagcagaagt
     8641 taagagtgct gtcaatcata caggaaacaa ggaagcagct aagaaagttg gagaattagt
     8701 tgctaaaaaa gctgttgaaa aaggaatcac tgaagttgta tttgacagag gtggatactt
     8761 atatcatgga agaattcaag aattagctga aggtgctaga gaagctggtc ttaagttcta
     8821 atacgaagga gggaaaaata catgctacgt cgtaagccga tagatgcagg acaacttgac
     8881 ttacaagaaa aagttgttga agtaagacgt gttactaagg ttgtaaaagg tggtagaaat
     8941 ttcagatttg cagcattagt agttgttgga gatgaaaacg gacacgttgg tataggtgct
     9001 gggaaagcaa tggaagtacc agacgctata aaaaaagcag ttgaagatgc taagaaaaat
     9061 ctaatagtag tgccaatagt tgggactaca attcctcacg aagtacgcgg acactttggt
     9121 gctggaaata tattaataat gcctgctgta gaaggtacag gagtaatagc tgggggacct
     9181 gctagagccg tacttgagct agctggacta aaagacgtta gagctaaatc tttagggtct
     9241 aacaatccaa gaaatatggt aaatgctaca atagaaggac ttaattctct aaaaacagtt
     9301 gaagatatag ctaaacttag aggtaaaaaa gttgaagaac ttctagggta aggaggtagt
     9361 gtaaaatggc taaattacaa ataaagttag ttagaagtgt tataggaact actcctaacc
     9421 aaaaaaagaa tgttgaagcg ttaggattaa gaaaaagaga acaagttgtt gtaaaagaag
     9481 acaatgctca aacaagaggt atgataaata aagtaagtca cttattagaa gtaactgaaa
     9541 tagctgaata atttttataa agtagtgcaa ggaggtgcaa tccatgaagt tacatgagtt
     9601 aaaacctgct gaaggtgcag taagagctaa gagaagatta ggtagaggta ctgcaactgg
     9661 acaaggtaaa actgcaggac gtggacaaaa aggtcaatgg tctcgttctg gtggtggagt
     9721 aagagtagga tttgaaggtg gacaaatgcc actagctaga agacttccta agagaggttt
     9781 caataacata tttaagaaag tttacacaga agttaatgtt gaagttttaa acagatttga
     9841 aaatggaaca gaaataactg cagaattatt aaaatctact aaaactataa gcaaaatagg
     9901 taaagacgga attaaaatct taggtgaagg taatttagag aaagctttaa ctgttaaagc
     9961 tgctaaattt acagcttcag ctcaagaaaa aatagaaaaa gctggtggaa aagcagagtt
    10021 agtataataa cctgctaatc tcctagccag tacaggcggg gtgaattagc gtgctgtcaa
    10081 aattaaaaca agcttggaag attaaagcag taagaaaaaa agtaatgtat acacttatga
    10141 tgatcgtgat attcagaata ggtactacta taccagttcc aggcatagac actagtatta
    10201 tacaaaagat ggtaggcggc aatagtctac tttctctgta taatatgttt actggtggag
    10261 catttagtaa cttttcacta tttgctttag gtataagtcc atatatcact gcatcaatca
    10321 taatacaact tctaacagta ggttttgaaa gtttagcaga acttcaaaaa tctggtgaag
    10381 aaggaaagaa aaaaatcaat aagtacacta aatatacagc actagctcta gcagttgtac
    10441 aagctttggg aattacatta ggaattgtaa gaagtgcttt aatatcaaat agtgtgtttt
    10501 ttatcacaac tgttgtaata acattagttt cagcaagtat gttagtaatg tggattgggg
    10561 acaaaattac tgaaaaagga atcggtaatg gtagttcagt aataatattt gcaggtataa
    10621 tatcaagaat acctacagat gttattaaaa tatcgcaaca agttaaatct gacgaagttg
    10681 caccttgggt tatagtgatt ctagctgtag ttatattact tacagtaaca ggagttacat
    10741 ttatacaaga agcaactaga aagatacctg tacaatatgc taaaagagtt gttggaagaa
    10801 aaatgtatgg aggacaaagt tctcatatac caatgaaagt taaccagtca ggagttatgc
    10861 ctataatttt tgctagttca cttttagctt tccctcaaac aatagctatg tttatgggtc
    10921 caaatgctca ggcttttgtt caaaaatact taagtatggc aacagaacaa ggattttgga
    10981 catatagatc aattgagatt ctacttataa ttttcttctc atatttttat acaactgtat
    11041 catttaatac agaagacata tctaaaaata tgaaaaataa tggtggattt ataccaggta
    11101 taagaccagg tgagcctact atggattatt taaatagaat tttaactaga ttaactttag
    11161 ctggagctac tttcttagca ataattgcta tggtgccagc tcttacaaca cattatatga
    11221 aagtaaatat gagtctagct gggacttcat tgctaatcgt tgttggagtt gctttggagc
    11281 ttaagagaca gttagagtca aacttagtta tgagaagcta tcaaggtttc ttaaaataaa
    11341 atggagatgg ataatatgag aataatatta cttggacctc caggtgctgg taaaggtact
    11401 caggcggcag gaatagtaga aaaatacaat atacctcata tatcaacagg agatatattc
    11461 agaaagaata taaaagaggg aacagaactt ggaaaaaaag ctaaagaata catggaccaa
    11521 ggtttattag taccagatga gttaactgta ggtttagtta ctgatagaat atctcaagaa
    11581 gattgtaaaa atggatttat gttagatgga tttccaagaa atgtagcaca aggagaacat
    11641 ttagatatct tcttaaaaaa tgctggtata tcactagata aagttgtcaa tattgaagtt
    11701 gataagagta tattagtgtc tagagcagtt ggtagaagaa tatgtaagtc ttgtggagct
    11761 acttaccatg ttgagtttaa tcctcctaaa gtagaaggtg tatgtgatgt atgccaagga
    11821 gaattatatc aaagagctga tgataatgaa gaaactgtat ctaagagaat acaagtttat
    11881 ttagatgaaa ctaagccttt agtagattat tatagcaaac aaggtataat agcagatata
    11941 aaaggtgatc aagcaataga taaagtattt gaagatattg tcgcagcctt aggaagtgga
    12001 aaataaatga ttatcttgaa atcaaaaaaa gaaatagaac ttttaagaga agcaggtaaa
    12061 atagttgctg acactcatga agttttaaga aaagctattt ctccgggaat atctacttta
    12121 gaattagata aaatagctga agagaatata agaaaataca atgcagaacc ttcttttaaa
    12181 ggatatggag gttttccagg aagtatatgt gcttctatca atagagaggt agtacatggt
    12241 attccaggag aaactatatt acaagaaggt gacattgtaa gtttggatat aggagcctat
    12301 tataaaggat atcatggtga ttctgcgaaa actcacggag taggcatgat atctgaagaa
    12361 gataggaaat tgatagaagt aactagagaa agcttctatg aaggaataaa atttgctaaa
    12421 ttaggatata gactttcaga tatctcacac gcagtacaaa cacacgttga gaaacatggt
    12481 ttctcggtag ttagagattt agtgggtcat ggagttggag caaatcttca tgaagaccca
    12541 caagtaccta attatggact cccaggaaaa ggaccaagac ttagagaagg aatggttatt
    12601 gctatagagc caatggttaa tgcaggtcgt tatcatgtaa agactctatc agatgggtgg
    12661 acgactgtta caatagatgg aaaaaaatca gctcattatg agcatacgat agcaattact
    12721 gaacatgaac ctttgatatt gacaaagttg taatttaaaa agtaggtgaa aaaagtgcta
    12781 tcagataatt taagtatagg tcaagttgtt aaagtttcat taggacgaga taaaggaaat
    12841 ttattctttg tagtcaaaat aattaataat gaatatgtat taatagctga tggaaaaaag
    12901 agaaaacttg acaaacctaa gttaaagaaa gtgaagcact taaaaaaata taattttatt
    12961 aatgatgaag ttagaaaaag agtagtatct ggacaagaga ttacagattc ttttttaaga
    13021 gctgaactta ctaagttaaa ttagataatt taacttattg aaatggaggg ctggttagtt
    13081 aatggccaaa aaagatgtta tagaattaga aggtacagtt tcagaagctt tacctaatgc
    13141 tatgttcaaa gttaaactag aaaatggaca tgagatatta tgccacattt ctggaaagct
    13201 aagaatgaac ttcataagaa ttcttgaagg tgacaaggtg aatgttgaac tttctccata
    13261 tgaccttaca agaggaagaa ttacttggcg taagaagtag actatattaa tatttagtct
    13321 aaggagggat taataatgaa ggttagacca tcagtaaaac caatatgtga aaaatgtaaa
    13381 gtaataaaaa gaaaaggaaa agtaatggtt atctgtgaaa atccaaagca taagcaaaag
    13441 caaggataag aaattattac tagcattttg ttaaatttta tagtataata ctatattgtg
    13501 atgttaacaa aagaacgtta aaatcgttga acaatctggc gtaggattgg catatgatgt
    13561 gaagttttaa acactaaaaa ctatgtgtag gaggtgcgat catggcaaga atagctgggg
    13621 tagatttacc tagagaaaaa agagcggaga taggcttaac ttatatatat ggtataggta
    13681 aagcaactgc taacgaaata ttagctaagg ctgagataaa tccagatact agaataaaag
    13741 atttatcaga agatcaagtt aatgagttaa gaaaagttat agatgacgat ttcttagttg
    13801 aaggtgactt aagaagagaa attgctttaa acataaagag attaagagat ataaaatgtt
    13861 atagaggaat aagacacgct aaaggtcttc cattaagagg acaaagaact aagactaatg
    13921 ctagaactag aaaaggtcct agaaaaacag tatctcgtaa aaagaaaaaa taaataaata
    13981 ataactagat gaaggaggga aaaggaaaat ggctaaacca aaaaagaaag ttacacgtat
    14041 tagaagaaga gaacgtaaaa atatagaacg tggtcatgct catatacaat caactttcaa
    14101 taatacaata ataactttaa ctgacgttca cggaaatgct atatcttggg caagttctgg
    14161 acaattagga ttcaaaggat caagaaaatc aactccattt gcatctcaaa tggctgctga
    14221 aacagctgca aaagctgcga tggaacacgg actaaaaagt gttgaggtat tcgtaaaggg
    14281 gccaggttca ggaagagaag ctgcaataag agctttacaa gcaactggac tagaagtaac
    14341 tatgataaaa gacgttactc caatcccaca taacggatgc agaccaccaa agagaagaag
    14401 agtgtaatta ataagagtac aataggaggt gtagataaat ggcaagatat acaggtgcat
    14461 catgtagaca atgccgtaga gagggaatga aattattcct taaaggtgat agatgttata
    14521 cagacaaatg tgctatagta aaaagaaact atgctccagg tcaacatggc caaggaagaa
    14581 agaaagtttc taactatgga ttacaattaa gagaaaaaca aaaagttaaa agaatatatg
    14641 gagttttaga gactcaattt agaaatttat atgaacgtgc tgaaaatatg cctggtaaag
    14701 caggtgagaa cttattaagt ttattagaga gaagattaga taatgtagtt tacagaatgg
    14761 gactagcatc ttctagaaaa gaagctagac aattagtgac tcatggtcat ttcactttaa
    14821 atggaaataa agtagacata ccttcattaa tagttaaggt tggagatgtt atagaagtta
    14881 aagagaaatc aagatcttct gcaaaattca aaaatttagt agaagttaac tcaagaatag
    14941 ctcctaagtg gttagaagct aatgtagaag gaatgacagc aaaagtagtt ggtgttccaa
    15001 caagagaaga tatagatctt gagatagcag agcacttaat catagaactt tactctaaat
    15061 aataagcaca cttttaaaaa ttattttaaa attttgttta ccctcagtgg attactgaat
    15121 tttaaggagg gttttgtcca tgatagaaat agaaaagcca aaagtagata tagttgagct
    15181 tagcgaagac tatagatatg gtaagtttgt tatagagcct ctagaaagag gatatggaat
    15241 aactataggt aacgcattaa gaagaatatt attatcatca ttaccaggtg tagcagtgaa
    15301 tgctataaaa atagatggag ttcttcatga attttcaaca atacctggtg ttaaagaaga
    15361 tgttactgag ataatattaa ctttaaaaga gctttcagca actatagatg gtgaaggaag
    15421 tagaacactt aaaatagaag ctcaaggacc atgctctatc acaggtgcag atataatctg
    15481 tcctccagat gttgaaatat taagtaaaga tttagcaata gctacattag atgataatgc
    15541 taaacttaat atggagatat ttgtagataa aggtagaggt tatgtttctg ctgaagaaaa
    15601 taaaacagag aatgttccaa taggtgtttt acctgtggat tcaatatata ctcctgttga
    15661 gaaggttagt tatcatgtgg aaaacacaag agttggtcaa aaaacagatt atgataaatt
    15721 agtactagaa gtttggacta atggtagtat aaatcctcaa gagggaatat cattagctgc
    15781 aaaggtatta gttgagcatt taaacttatt tatagactta actgaacatg taagtagtgt
    15841 tgaaatcatg gtagaaaaag aagaagatca aaaagaaaaa gttcttgaaa tgactataga
    15901 agaattagat ttatcagtta gatcatataa ctgtttaaag agagcgggaa ttaatacagt
    15961 tgaagaatta gctaataaat ctgaggatga tatgatgaag gttagaaacc taggtaagaa
    16021 gtcattagaa gaggtaatac aaaaactaga agaacttgga ttgggattaa aaccaagtga
    16081 agaatagcga gcaaaggagg gataagaatg gctaagtacc gtaaattagg acgtgaaaca
    16141 gctcacagaa accttatgtt aagaaactta gtaacttgct tactaagaag tggaagaata
    16201 gaaactacag tgactagagc gaaagaaact cgtagaatgg ctgaaaagat gataactctt
    16261 gctaagagag gagatcttca tgctagaaga caagttttag cttatgttat ggatgaaaca
    16321 gtagttaata acttattcac agatttagct ccaaaatatg ctgagagaaa tggtggatac
    16381 actagaataa taaaaatagg gccaagaaaa ggcgatgctg ctgaaatggc ttttatagaa
    16441 ttagtatagt aaggaaagga ttaggcttga tggcttaatc ttttttttat ttttttgact
    16501 aaggtatgat ataataatgt gtaaaatgat ttttataagt tattgcttac taaaaggagt
    16561 atgagttaat ggataatata gtaaaggtaa ataatatttc gtttgagtat attacagatg
    16621 aagcaaaact taaagcaata gataatttaa gcctagatgt taaaaaagga gaatttgttg
    16681 cgataatagg acataatggt tctggtaagt ctactttatc taaaaactta aatgctattc
    16741 ttatgcctac tgaaggaaat attcttattg atgatatgga tactaaagaa gaagaaagat
    16801 tatgggatat aagacaaact gcaggcatgg tatttcaaaa tccagataat caaatagttg
    16861 ctactatagt agaagaagat gttgcatttg gacctgagaa cttaggtata gaaccaaaag
    16921 aaataagacg aattgtagag gagtctttaa aaagtgtagg tatgtatgat ttaagagata
    16981 gacagcctca tttgttatca ggaggtcaaa agcaaagagt tgcaatagca ggaattattg
    17041 ctatgaggcc taaatgtata atatttgatg aagcaacagc aatgttagat ccatctggaa
    17101 gaaaagaagt tatgaaaaca ataaaaagac ttaataagga agaaaatata actgttatac
    17161 atataacgca ctttatggaa gaagcagtag aagctgatag agttgtagtt atggaaaaag
    17221 gaaagaaaat cttagaggga actcctagag aagtattcag taaaataaag atgttaaagg
    17281 aaatcggttt agatgtacct tgtatgacag agttatctag tttattaata gaagaaggta
    17341 taaatattag tagtgatata ttaactgtgg atgagatggt gatggaatta tgtcaattat
    17401 agtaaagaat ttaacacata tatataatga agggatgcct tttgcaagta aggcacttga
    17461 tgatgtttct tttgagatta aagatagaga ttttgttggt cttataggtc atacaggctc
    17521 aggaaaatct acattaatac aacatttaaa tggattacta aagccttcct caggagaaat
    17581 atttataaat gattttaata taacagataa aaacttgaat ttaactgaga ttagaaaaag
    17641 agtaggggtt gtatttcaat atccagaata ccaattgttt gaagaaacga ttgataaaga
    17701 tatagctttt ggaccctcta atttaggctt agaggagtct gagatacata acagggtaaa
    17761 agcatcaatg gaagctgtag gacttgatta tgagggattt aaagacaaat ctccttttga
    17821 attatctggg ggacaaaagc gtagagtagc aattgctgga gttatagcca tgaacccaga
    17881 agttctcata ttggatgaac caactgctgg tcttgaccct ggtggaagag atgaaatttt
    17941 taacttaata aaagacttac atgaaaaaaa gaatatgact ataatactat catcacatag
    18001 tatggatgat atggcaaagt tagcaaaaac tttaattgtt atgaatcatg gtagcgtaga
    18061 atttatggga actcctagag aagtatttaa atcaaatgct agtaaattaa aagatatagg
    18121 attagatatt ccacaagttt tagagcttgc attgaaattg agagaaaaag gctttgacat
    18181 cagtgaggat atattgactt tagaagaagc aaaacaggaa atattaaaag ttgtgagagg
    18241 acgaggatta tgttaaaaga tataactata gggcaatact acccaacaag ttctgctatt
    18301 cataaattag atccaaggat aaagcttgta gcgacaattg tatttatggt atctatattt
    18361 gtagtaaata aattttggcc ttatatagta gttttattat gtttattagc tatgataaaa
    18421 ttggctaata taccagtcaa atatattgtt aagggtgtta aacctcttaa atggattatt
    18481 ttgtttacat ttcttataaa tatttttttc ttaccaggtg atgaaatatg gtcatttgga
    18541 tttttagcta ttacaaaaca gggtctaaga caagcaattt ttatggcaat aagattaata
    18601 tttttagtag ttggtacatc attgcttact ttaacaactt caccaataga attaactgat
    18661 ggaatagaga gattgttgaa tccatttaag aaaattggtt tgccagttca tgaacttgca
    18721 atgatgatga caattgcttt acgttttatt cctacattgt tagatgagac agacaaaata
    18781 atgaaggctc agatgtctag aggtgcagat tttgaaagta agaatcttat aaatagagca
    18841 aagaatttag taccactttt ggtaccttta tttgtaagtg catttagaag agctgatgaa
    18901 ttggctatgg ccatggaggc cagatgttac agaggtggac ataataggac taagatgaga
    18961 gagtctgtta tatcaagaag ggattatatg gcatgtgtat ttcaggttgt ttatctggga
    19021 gcaattatag ctactagatt tatagcaatt taattaataa gttatagata taatgaggta
    19081 aagtatgaga aatataaaaa ttaaaataca atacaatggt aagaattatt gtggatggca
    19141 aaagcaacct gattctttag ggatacaagg tacaattgaa agggctatat atgatataac
    19201 aaaagaagaa accagtctta tagggtctgg tagaactgat tcaggagttc atgctattgg
    19261 tcagattgca aattttaaaa ttaattcagg tataagtata gaaagtatac caatggcact
    19321 aaatgccaag ttgccaaaag acatatcagt tatagaagca tgtgaagtaa atgatgattt
    19381 tcactccaga tacagtgcaa aaggtaaaac atataaatat ttagtatata atagcaagtt
    19441 tagaaatcca atacttagtg agatatcata tcaagtaaaa tatgaacttg attttgataa
    19501 aatgtgttca gaagcaaaaa gtttattagg aacacatgat tttaaaggtt ttatgagttc
    19561 tggttcatct gtaaaagata cagttagaac gatatatgat attgatataa gtaaaaaaga
    19621 tgacttgatt acttttgaga ttagtggtaa tggtttttta tataacatgg tgaggattat
    19681 tgttggaaca cttgttgata tgggtcgtgg cagaattaac gaaccatttt tagatataat
    19741 acaatcaaaa actaggtcaa gatgtggaca tacagctcca gcacaaggat tatttctcaa
    19801 aaaagttcat tattaacttg acacaccagg ctacatgtat taaaatatat gagaatgtgt
    19861 taataagtcc acttgccccg gacttgacat aaacggtaaa aaaattttat gaaaagtagt
    19921 taaggaggga cagttatgaa aagttatata gctaagccag ctgatgtaca aagaaaatgg
    19981 tacttagttg atgctgaagg aaaaacatta ggtcgtttag caacagaaat tgcgacagta
    20041 ttgagaggta aacataaacc aacatttact cctcacgttg atggtggaga ttttgttgtt
    20101 gtagtaaatg cagaaaaaat agttttaagt ggtaagaaat tagatcaaaa atattacaga
    20161 taccatactg gttatgtagg tggattaaaa gaaatatctt acagagatat gatggataag
    20221 aaaccagaag aagttatatc acatgctgta agcggtatgt tacctaaaaa taaattaaga
    20281 agcagaatga tgactagatt aagagtattt gcaggtgctg agcacactca tgcagctcaa
    20341 aatccagaag ttttaaactt taaataagat taataggtga aaggaggagt ttataatggc
    20401 taacgttcaa tattatggaa ctggaagaag aaaaagttct gttgctagag taagactagt
    20461 tgcaggtgaa ggaaatatat tagtaaatgg aagagcatta gaaaattatt ttaattatga
    20521 gacattaata agagatgtta aacaaccatt agttttaact ggtaatgaaa ataaatatga
    20581 tgttatagta aaagttgaag gtggaggatt cactggacaa gctggagcta taagacatgg
    20641 aatatctaga gctttattaa aagctgattt agatttaaga cctgctttaa agaaagaagg
    20701 tttcttaact agagatgcaa gaatgaagga aagaaagaaa tacggattaa aagcagcaag
    20761 aagagctcca caattctcaa aaagataatt acttattttt ttggaaaagc aaaatccttt
    20821 atttactgtt attcagaaag tattggtatt ttaaaaatgt tgggttaagt taattattga
    20881 tatataataa aataataaga tatcttatta ggatgttttt cattaagaag aacatccttt
    20941 ttattttgac tatttaataa aaaacatatg ctaataacat ttaaatttta tttttataat
    21001 attgtaattt aaaagtttat ataaggttat atattttaag atattattta acaatataaa
    21061 ttctgaatat acgttatcaa aatttataat ataaactaag tataatttat tgtatagtat
    21121 tgaatgttag ataaacatag tgaattaaat agggacagaa atataatatc attacataat
    21181 aatatattaa taccaataaa taaagatata tcaatattaa aaaaatttaa atgtttgtac
    21241 taatatatgg aatattatag tgtttttata agtatacata tacagggtga tgttgtgaga
    21301 aagtacataa aacatataat ttttagtttt gcaatgatat gtctagtagt agtatccata
    21361 tttgaaatta aaaatatttc tgaagatgtt atcaagtata tgccagtaac aaacaaaact
    21421 ataattttag atgctggtca tggaggcatt gatccaggtg cattaaataa ggataagagt
    21481 acatctgaaa aggatattaa cctagcaata acacttaagc ttagagagct tatagaatca
    21541 agtggtggcc ttgtaatatt aactcgagaa gatgacagta gcctttataa agaagaaaat
    21601 aataaaacta caagacaaaa atataatgag aatttgaaaa atagaaaaga aataatatct
    21661 aattctaatg ccaatatgtt tgtctctata catcttaatg catttgaaca atcaaaatac
    21721 tatggagctc aaacttttta tcctaaagac aaacaagaca gtaaagaatt atcgaagtgt
    21781 attcaagaag aacttaaaag agtagtagat aagacaaaca acagagaagt caaaccaagg
    21841 gatgatatat atcttttgaa agaaaataat attccatcag tactgataga atgtggtttt
    21901 ttatcaaatg aaaaagagtg taaactctta actgatgaaa catatcaaga aaaaatagca
    21961 tgggcaatct acataggaat acaaaaatat ttaagttgaa ataactataa aaataggtct
    22021 aaatatgtaa atagcttgta ttaaagcagt taaaatgcat taatataggc tatttttatt
    22081 ttgacaaaaa aatatttaaa ataaaagtta aaaagttgtt gacttagaat aatatagatg
    22141 atattatata tgagtgccca aaaggagcac caaaataaga caaa
//
LOCUS       DAFAZV010000061        20588 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFAZV010000061 DAFAZV010000000
VERSION     DAFAZV010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20588
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.061"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            27..101
                     /locus_tag="KOU88_003393"
     tRNA            27..101
                     /locus_tag="KOU88_003393"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KOU88_003394"
     tRNA            116..200
                     /locus_tag="KOU88_003394"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KOU88_003395"
     tRNA            210..293
                     /locus_tag="KOU88_003395"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            317..391
                     /locus_tag="KOU88_003396"
     tRNA            317..391
                     /locus_tag="KOU88_003396"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:349..351,aa:Gly,seq:gcc)
     gene            416..492
                     /locus_tag="KOU88_003397"
     tRNA            416..492
                     /locus_tag="KOU88_003397"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:450..452,aa:Arg,seq:tct)
     gene            500..575
                     /locus_tag="KOU88_003398"
     tRNA            500..575
                     /locus_tag="KOU88_003398"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:533..535,aa:Gln,seq:ttg)
     gene            584..659
                     /locus_tag="KOU88_003399"
     tRNA            584..659
                     /locus_tag="KOU88_003399"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:617..619,aa:Lys,seq:ttt)
     gene            662..750
                     /locus_tag="KOU88_003400"
     tRNA            662..750
                     /locus_tag="KOU88_003400"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Ser,seq:tga)
     gene            754..829
                     /locus_tag="KOU88_003401"
     tRNA            754..829
                     /locus_tag="KOU88_003401"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:787..789,aa:Phe,seq:gaa)
     gene            836..909
                     /locus_tag="KOU88_003402"
     tRNA            836..909
                     /locus_tag="KOU88_003402"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:870..872,aa:Met,seq:cat)
     gene            924..1000
                     /locus_tag="KOU88_003403"
     tRNA            924..1000
                     /locus_tag="KOU88_003403"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:958..960,aa:Ile,seq:cat)
     gene            1018..1094
                     /locus_tag="KOU88_003404"
     tRNA            1018..1094
                     /locus_tag="KOU88_003404"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1052..1054,aa:His,seq:gtg)
     gene            1103..1178
                     /locus_tag="KOU88_003405"
     tRNA            1103..1178
                     /locus_tag="KOU88_003405"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1136..1138,aa:Lys,seq:ttt)
     gene            1186..1259
                     /locus_tag="KOU88_003406"
     tRNA            1186..1259
                     /locus_tag="KOU88_003406"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1218..1220,aa:Cys,seq:gca)
     gene            1267..1343
                     /locus_tag="KOU88_003407"
     tRNA            1267..1343
                     /locus_tag="KOU88_003407"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1301..1303,aa:Arg,seq:acg)
     gene            1356..1431
                     /locus_tag="KOU88_003408"
     tRNA            1356..1431
                     /locus_tag="KOU88_003408"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1389..1391,aa:Val,seq:tac)
     gene            1507..1920
                     /locus_tag="KOU88_003409"
     CDS             1507..1920
                     /locus_tag="KOU88_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213245.1"
                     /translation="MYIVIGNEIVDSEELKIIIDKNSEFKVEKDLSKSTKREDVIAYQ
                     LSIDLNYLDSLINEQCNLASLSDEEKFDEYMTLSDELALDLEELMPKYTIINARAYKL
                     DEVYGIVKIILAVAYADLGHLKLSDVVKRLSRQVD"
     gene            2229..5660
                     /locus_tag="KOU88_003410"
     CDS             2229..5660
                     /locus_tag="KOU88_003410"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBK3213246.1"
                     /translation="MLKKFNKILVANRGEIAIRIFRACSELGIKSVGIYSKEDKYGLF
                     RTKADESYLIGEGKGPIDAYLDMDGIIDLAKRKKVDAIHPGYGFLAENAEFARKCEEN
                     GITFIGPSSKVMNMMGDKINSKKIAKEVNVQTIPGVEKAIRSTEEAKEVANKIGYPVM
                     IKASNGGGGRGMRIVHREEDLELEYETACSESRKAFGEDIIFIEKYIADPKHIEVQIL
                     GDNYGNIVHLYERDCSVQRRHQKIIEYAPAFSLDDKVRKEICEDAVKLSKHVGYSNAG
                     TLEFLVDANGGHYFIEMNTRVQVEHTVTEMVTGIDIVQSQILIAQGYSLDSEEINIKS
                     QDDVEIRGYSIQCRITTEDPKNKFMPDTGKIQVYRTGSGFGIRLDGGNGFTGANISPH
                     YDSLLVKTISWDRTFQGAINKTIRSIKELRVRGVKTNVGFLVNVLNNPIFSNGKCSTK
                     FIDENPDLFEITESKDRGTKLLQFIGDVIVNDNACKEKPLFDALHDPRMDKDGSKSEG
                     SKILFDKLGKSAYIEKIKNDKKLLLTDTTMRDAHQSLLATRIRTYDLLKAAKPTEKYQ
                     KDLFSLEMWGGATYDVAYRFLKESPWRRLQKLREEIPSIMFQMLLRASNGVGYKNYPD
                     NVIEEFTKESARQGIDVFRIFDSLNWVENMKPSINTALETGKIVEATMCYTGDILDKT
                     KTKYNLEYYIKMAQELESLGADIIAIKDMSGLLKPYSAYTLVKELKKNVKAPIHLHTH
                     DTSGNGVATCLMASEAGVDIIDAALESMAGLTSQPSLNAIVEALKNTERDTGIDLFGY
                     DELGKYYKDLRKVYNKFESDLTNSCAEIYNFEIPGGQYTNLKPQADSLGLVNRFDEVK
                     EKYKEANEVVGDIIKVTPSSKVVGDLAIFMTKNKLDKDNIIEEGKNLSFPDSVVDYCK
                     GMIGQPEGGIPKDLQEVVLKGEEAITVRPGSLLPAEDFDEIAKYLNEKYDINANIRNV
                     ISYALYPKVYEDYIKHLQHYNDISKLESDVFFYGLNKNEECEVEIEEGKVLTIRLVEI
                     GEVKENGFRTIGFELNGMVREVEIKDKNFSGKINNVEKADMNDPLQIGASIPGKVIKI
                     MVKEEDEVKANQPLIVIEAMKMETIIVAKTDGVIKSIKVKEDDMVEDKQLLMIMK"
     gene            5902..7830
                     /locus_tag="KOU88_003411"
     CDS             5902..7830
                     /locus_tag="KOU88_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBK3213247.1"
                     /translation="MKVYDSKMLRNVAVLGHSGCGKTNLIETIAYTANTNKIPKLTDK
                     VNMTYSMGLIPIEYNDYKFNLLDTPGYFDFSGDVVSSLRASDAAIIVIDATAPIQVGT
                     EKSLELTESIPKIMFINKIDNEKARYKDAIAMLREKYNNKIVPMISPIYKDKNFVKLH
                     NVFENIDDLEGEFKEQAMSVKEALMELIAETDDQILDKYFNGEELTTEEIQKGIIIGI
                     QRGDIIPVICGSTINNIGTKEILDTISSYLEPIFTEESKPFRGLVFKTMVDPFVGKMS
                     YIKITEGVLSKDKDVFNINKNVKEKIANIYTLRNSELVEIEKAKAGDIVVITKVNSLK
                     TGDTISADKDAEALEKIDFPKPQIYYAVTPKNKGDEEKVASVLNKLVEEDPTLHWYRN
                     TETKQALLGGQGELHIKTIKNKMKDKFGVDVELNDLKVPYRETIKGTADVQGKHKKQS
                     GGHGQYGDVKIRFERCESDFEFTEEIFGGSVPKQYIPAVEKGLKDSMQKGILAGYPVT
                     NIKATLYDGSYHDVDSSEMAFKMAASAAFKKGMEEAHPILLEPIMKLKITVPEEYMGD
                     VMGDINKRRGKIFGMEPDDKGKQIIFAEAPQAETFKYAIDLRAMTQGRGYFEMELERY
                     GEVPSQFAEKIIGLATAK"
     gene            8283..8747
                     /locus_tag="KOU88_003412"
     CDS             8283..8747
                     /locus_tag="KOU88_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBK3213248.1"
                     /translation="MATMTDIIEKFIKDLMEEDNSIQIQRNELANLFSCAPSQINYVL
                     TTRFTIDRGYYIESKKGGGGYVQIEKIRKSKDGHIRELLNEKIGSQISYKKAKELLEG
                     LKESDLINERELKLILYAIDDKSLCMPIYELKEKVRSNILKNIIIGLFSIEE"
     gene            8754..9248
                     /locus_tag="KOU88_003413"
     CDS             8754..9248
                     /locus_tag="KOU88_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HBK3213249.1"
                     /translation="MLCQKCNKNKASVYYNKIVNGEKTEMYLCSECAKENTEMNFNLD
                     MPFSMMDIFSNLGFQPKKELEEKLVCPKCNTTYSEFKNNGRFGCSECYNVFSSQVNPM
                     LQNIHGHIEHTGKAPKKSFYKISVENEIKELKEDLDRAIKNEEYELAAQFRDKIKYLK
                     GSID"
     gene            9264..10289
                     /locus_tag="KOU88_003414"
     CDS             9264..10289
                     /locus_tag="KOU88_003414"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HBK3213250.1"
                     /translation="MKENIVMKSRVRLARNLNNYPFPNKLDKECAMEIIEKVKNAFIN
                     SNLEQKEEFDFYKIEDLDQSKKMLMVEEHIISPDLAENDKSAVIVKKDKTISIMINEE
                     DHIRIQTICDDLNLEYAYSVANEIDDLLESSLEYAFNTKLGYLTSCPTNTGTGMRASV
                     MMHLPALSQLGYMDELYKISSQIGIAIRGIYGERTEALGNIYQISNQLTLGRTESNII
                     ENVSGLTKDAISKEIKAREILQKKLGIKLEDKIFRSIGTLENSRVMSSAEAMSHLSNI
                     KMGIEMNYIDKLDLRAIEQLMIGIQPAHQSIMYKSDDVENRDINRATYIRETLEKLRG
                     GMNCELQ"
     gene            10276..12723
                     /locus_tag="KOU88_003415"
     CDS             10276..12723
                     /locus_tag="KOU88_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBK3213251.1"
                     /translation="MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEG
                     IAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVLSPRSKQILELSGMFANKLKTNY
                     IGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
                     NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVG
                     KTAIAEGLATNIALGNVPETLKNKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKN
                     GNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGATTIDEYRKHVEKDS
                     ALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRY
                     LPDKAIDLIDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRD
                     EQGLLKKQLEDVRERWNKSSKHSDLVDGEVIAEVVGLWTGIPVNKILEEEADRLLRLE
                     EILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELSKALAEV
                     QFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEI
                     EKAHPDVFNILLQILDDGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAK
                     GDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVFHSLNENHISKIVLLMAAKLQ
                     ERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKG
                     SNVVAKVKDEKIVFETK"
     gene            12903..14276
                     /gene="radA"
                     /locus_tag="KOU88_003416"
     CDS             12903..14276
                     /gene="radA"
                     /locus_tag="KOU88_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBK3213252.1"
                     /translation="MAKIKTKYVCQSCGYETAKWLGKCPECTKWNTFVEEIDQKSTKK
                     EVFIIDKSSSKPVSINSIESKEEERFTTDINELDRVLGGGIVKGSLVLVGGDPGIGKS
                     TLLIQVSSNVANLGKTVLYITGEESESQIKMRAKRLGINSENLYIFAENNLSIIESYL
                     ESVNPELIILDSIQTVFSPEISSAPGTVSQIKEGTSKFMKISKKMGISTFIVGHVTKE
                     GSLAGPKLLEHMVDTVLYFEGERYNTYRLVRAVKNRFGSTNELGVFEMRDLGLVELDN
                     PSKILISEKPKDVAGSVIISTVEGTRPMLLELQALVSPTSFGIPKRTSTGVDYNRVGM
                     LLAVLEKRVGLQIQNQDVYINIVGGIKINEPSIDLGIAISVASSFRNIPIDEDIAVTG
                     EVGLTGEVRAVSFIEKRIAECKKLGFKKIVVPRSNYDVVKETKGIEIWPVDNLRQAIN
                     IVLGRNQ"
     gene            14279..15349
                     /gene="disA"
                     /locus_tag="KOU88_003417"
     CDS             14279..15349
                     /gene="disA"
                     /locus_tag="KOU88_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA integrity scanning protein DisA"
                     /protein_id="HBK3213253.1"
                     /translation="MENFLDNKNMLYALKMISPGTPLRLGLNNVLRAKTGGLIVIATN
                     EDVMKIVDGGFAINAEYSPSYLYELAKMDGAIVLSGDVKKILFANAQLIPDYFIETSE
                     TGTRHRTAERVAKQTGAIVIGISQRRNVITVYRGNEKYVVEDISKIFTKANQAIQTLE
                     KYKTVLDQAVTNLNALEFNDLVTIYDVALVMQKMEMVMRVTSIIEKYVIELGDEGTLV
                     SMQLEELMGTTRIDQKLIFKDYNKENTEIKELMKKVKNLNSEELIELVNMAKLLGYSG
                     FSESMDMPIKTRGYRILSKIHRLPTAIIENLVNYFENFQQILDASIEELDEVEGIGEI
                     RATYIKNGLIKMKQLVLLDRHI"
     gene            15438..16532
                     /locus_tag="KOU88_003418"
     CDS             15438..16532
                     /locus_tag="KOU88_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBK3213254.1"
                     /translation="MIRKVTRILFILLGFTIGITTYLTLMKDFEILTFGKETYGYIAA
                     VVAGIIIAILGYLIEPWVVNKVKEIAKIVDKELSKYPQTDILLGSMGLIVGFVIAYLL
                     SGLVNRIPIVGGILSLLLYLFLGYLGMKVALKSKNDLFNIGKLGRLANPIKDKDKDKE
                     NKKEVKAIPPKVLDTSVIIDGRIADICKTGFIEGKLIIPAFVLEELRHIADSSDDLKR
                     VRGRRGLDILNIIQKELNIEVEISERDFDDIAEVDSKLLKLAQVLNGKVVTNDYNLNK
                     VAQFQGVEVLNINELANAIKPVAIPGEDMVVQVVKEGKEAQQGVAYLDDGTMIVVDGG
                     RKYMNETIKVLVTSVLQTPAGRMIFAKPKN"
     gene            16661..18838
                     /locus_tag="KOU88_003419"
     CDS             16661..18838
                     /locus_tag="KOU88_003419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213255.1"
                     /translation="MRKKIISFLATFIIILTSASQYSFADDISTRGKVIFIDMNRTSM
                     SNMLRIKSLREELDNRGYIGLMNIRGDKGSDDRRSYASMGAGGRANVANEEDINFESS
                     SKDRNIVFESATGKSAKGINNLTINKSINENLNFGEYGSVLGSLGQSLSDNGLKASVL
                     GNSDIIENGQLIKNRNLCLTAMDEYGRIPNGNVDTINKKDLSMPYGISTDYDKLIVET
                     KEAYKNNDVIFVELGDTYRLDLYKPNLNEKTYESMKDNIEKNIDIYLKNIFSMVEEND
                     TVYIASAFPSDLDYKNKRRLSPIIKLNGEGKGILSSSTTRREGIVTNLDVGVEILDNF
                     NIKNQNMVGRKYELINRDDNKEFLMDEYQKIVSISSIRSTILNGFVSIVFLSWIVAMI
                     AILFRKHISKNYKETTFFILKELLKIGIVMPLSFMITPIMNFKTPLAISLGIIIITLT
                     IYLISKVLIKNDLKNMLFFTGLTIVIMVIDAGFGSYLMKSNVMSYDCIIGARYYGVGN
                     EYQGVAIGSAIFTFAILLTYKNIPKWSIIVFSLVILITSASPIMGANVGSAISECVAF
                     LLFILLIYNVKIDFKKIVLLGIAVLFVLGVFVAIDMILGSNSHLGMFVKEIYFNGPGE
                     IIQTFSRKIEMNLKLAQTSAWVNILLTGIGVILVLMINQIRYFKQLMDEYPIVFKGFI
                     ASIAGCLVTLLVNDSGIVSSATAFIYVIVPMITLSINLTALKE"
     gene            complement(19024..19794)
                     /locus_tag="KOU88_003420"
                     /pseudo
     CDS             complement(19024..19794)
                     /locus_tag="KOU88_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425570.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(19903..>20588)
                     /locus_tag="KOU88_003421"
     CDS             complement(19903..>20588)
                     /locus_tag="KOU88_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3213256.1"
                     /translation="GRILNATISKEPSGRYYVSLCCTDVDIEAFENTNNHIGLDLGIK
                     EFCISSCGEFIENPKYLKKSLNKLAKLQRELSRKTIGSLNRNKARLKVARLQEHIANQ
                     RNDFLQKLSTKLIKENDIICIEDLQVKNMIRNRKLSRLISDVSWSEFIRQLEYKANWH
                     GRQIVKVGKFFASSQICNKCGYKNEEVKDLNIREWICPSCNETHDRDINASINILKEG
                     LRLITIQNK"
BASE COUNT         8264 a         2366 c         3799 g         6159 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atataaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttat
      301 ttaatttaat aaacgagcgg gaatagttca gtggtagagc gcaaccttgc caaggttgaa
      361 gtcgcgagtt cgaatctcgt ttcccgctcc aaattttatg tttatgttgt aatgtgggtg
      421 catagctcag ctggatagag caacgccctt ctaaggcgtg tgtccggggt tcgaatccct
      481 gtgcgctcac cacatatatt ggggattagc caagtcggta aggcacatga ctttgactca
      541 tgtatgcgta ggttcgagtc ctgcatcccc agccaaacag tatggtctat tagctcagtc
      601 ggtagagcac ctgactttta atcagggtgt cccgcgttcg agtcgcggat agatcaccaa
      661 tggagaggtg tccgagtggt ttaaggagct ggtcttgaaa accagtgact tcgaaagggg
      721 ccgtgggttc gaatcccacc ctctccgcca aatgcccaga tagctcagtc ggtagagcag
      781 gggactgaaa atccccgtgt cggtggttcg attccgcctc tgggcaccaa aatgtggcgg
      841 tatagcttag ttggctagag cgttcggttc atacccgaaa ggtcataggt tcgactccta
      901 ttaccgctac taaaatttaa tgtgggccat tagctcagtt ggttagagcg cccggctcat
      961 aaccggtagg tctggggttc gagtccctga tggcccacca cattaaatta acttatggtg
     1021 ggtatagctc agttggttag agcgccagat tgtggctctg gaggtcgtga gttcgactct
     1081 cattatccac cccaacttat atggtctatt agctcagtcg gtagagcacc tgacttttaa
     1141 tcagggtgtc ccgcgttcga gtcgcggata gatcaccaaa aaggcggcga catagccaag
     1201 tggtaaggca gtggactgca actccttgat ccccagttcg aatctgggtg tcgcctccaa
     1261 taaaatgcgc tcatagctca actggataga gtgtctgact acgaatcaga aggttagggg
     1321 ttcgagtccc tttgggcgca ccatatgaat agcgagggat tatagctcag ctgggagagc
     1381 acctgcctta caagcagggg gtcacaggtt cgagccctgt taatcccacc agtgcaaacc
     1441 tctagtaaaa ctactagagg ttttattttt gattgaaaaa atttttatat ttaggaggta
     1501 aaaaatttgt atatagtaat aggaaatgaa atagttgata gtgaagaact taaaataatt
     1561 atagataaaa atagtgaatt taaagttgaa aaagatttaa gtaaaagcac aaaaagagaa
     1621 gatgtaatag catatcagtt aagtatagat ttaaattacc tagattctct tataaatgag
     1681 caatgtaatt tagccagtct atctgatgaa gagaaatttg atgaatatat gactttgtct
     1741 gatgaacttg cactggattt agaagagtta atgccaaaat atacaataat aaatgctaga
     1801 gcatataaat tagacgaggt atatggaatt gtaaaaataa tactagctgt agcgtatgca
     1861 gatttagggc acttaaaact ttctgatgta gtaaagaggc tatctagaca agtagattag
     1921 gatatgaata tgaactatat taaaaaaatg tataaaatct tacgtaaaga tgaaaataat
     1981 tatgtaaaca tagaaaaaaa cagtataaaa tcaagtcaat tgtagaaatt ttcacataaa
     2041 ttcatctgaa attctataaa aaatgcctta attttaatga ggtaaatcga gtttacacag
     2101 tctaaaaatt acttatattt ataaatttat cttattaatt aaggaacttt cttaaacatc
     2161 ttcaaaaata aagtatttta gtctataatc tttaatatta cacaaacaat aaaggagaag
     2221 aatagagtat gcttaaaaag tttaataaaa tactagtggc taatagaggc gaaatagcta
     2281 taagaatatt tagagcctgt tcagaattgg ggataaaaag tgttggtata tacagtaagg
     2341 aagataagta tggattgttt agaacaaaag cggatgaatc atatttgata ggagaaggta
     2401 aagggccaat agatgcatat ttagatatgg atggaataat agacctagca aagagaaaaa
     2461 aagttgatgc tatacatcca ggatatggtt ttctagcgga gaatgcagaa tttgctcgta
     2521 aatgtgaaga gaatggaatt acttttatag gaccatcatc taaggtaatg aatatgatgg
     2581 gggataagat taactctaaa aaaatcgcaa aagaagttaa tgttcaaact ataccaggag
     2641 tagaaaaagc aataagaagt actgaagaag caaaggaagt tgcaaacaaa ataggatatc
     2701 ctgttatgat aaaagcatct aatggcggtg gcggtagagg tatgagaatt gtacatcgcg
     2761 aagaagactt agagcttgaa tatgaaactg cttgtagtga atcaagaaaa gcttttggag
     2821 aagatattat atttatagaa aaatatatag ctgatccaaa acatatagaa gttcaaatat
     2881 taggtgataa ttatggaaat atagttcact tatatgaaag agattgttca gttcaaagaa
     2941 gacatcaaaa aataatagaa tatgcaccag ctttttcgtt agatgataaa gtaagaaaag
     3001 agatatgtga agatgcagtt aagttatcaa aacatgtggg ttattctaat gcgggaacat
     3061 tagaattttt agtagatgca aatggtgggc attattttat agagatgaac acaagagtac
     3121 aggttgaaca tactgtaaca gagatggtta caggaataga tatagttcaa agtcaaatac
     3181 taatagccca aggttacagc ttagatagtg aagaaattaa tataaaatca caagatgatg
     3241 tggaaataag aggttactct atccaatgta gaataactac agaagaccct aagaataaat
     3301 tcatgcctga tacaggtaaa attcaagttt atagaactgg ttcaggattt ggtataagac
     3361 tagatggagg aaatggattt acaggggcaa acataagtcc tcattatgat agtttattgg
     3421 ttaagacaat atcttgggat agaacattcc aaggagcaat aaataaaact ataagatcta
     3481 taaaagaact tagagttaga ggtgttaaaa ctaatgtagg attcctagtt aatgttttaa
     3541 ataatcctat attctcaaat ggtaaatgta gtactaagtt tatagatgaa aatccagatt
     3601 tatttgaaat aacagaaagt aaagacagag gaacaaaatt acttcaattt ataggagatg
     3661 taattgtaaa tgataatgct tgtaaagaaa aaccattatt tgatgcatta catgacccaa
     3721 gaatggataa ggatggttca aaatcagaag gaagtaaaat acttttcgat aagttaggta
     3781 aatctgcata tatagaaaag ataaaaaatg ataagaaatt actattaaca gatacaacaa
     3841 tgagagatgc acatcaatca ttattagcaa caagaataag aacatatgac ttattaaaag
     3901 ctgctaagcc aacagaaaaa tatcaaaagg atttattctc acttgaaatg tggggaggag
     3961 ctacttatga tgttgcatat agatttttaa aagaatctcc ttggcgtaga ttacaaaagc
     4021 taagagaaga aataccaagc ataatgttcc aaatgttgct tagagcatca aatggagttg
     4081 gatataaaaa ctatccagat aatgtaatag aagaatttac aaaagaatct gctagacaag
     4141 gtatagatgt atttagaata tttgattcat taaactgggt tgaaaatatg aaaccatcta
     4201 ttaatacagc tttagaaact ggaaaaattg ttgaagcaac tatgtgttat acaggtgata
     4261 tactagataa gactaaaact aaatacaatc tagaatatta tattaaaatg gcacaagaat
     4321 tagaaagctt gggagcagat ataatagcaa taaaagatat gtcaggtctt cttaaaccat
     4381 attcagctta cacactagtt aaagagttaa agaaaaatgt aaaagcacca atacatttac
     4441 acactcatga tacaagtgga aatggtgtag caacttgttt aatggcgtca gaagctggag
     4501 tagacataat tgatgctgca ttagaatcta tggcaggact tacaagtcag ccatcactta
     4561 atgctatagt agaggcactt aagaatacag agagagatac aggaatagat ttatttggat
     4621 atgatgagtt aggaaaatat tataaggatt taagaaaagt ttataataaa tttgaaagtg
     4681 atttgactaa ttcttgtgca gaaatatata attttgaaat accaggaggc caatatacaa
     4741 acttaaaacc tcaagctgat agtttaggat tagttaatag atttgatgaa gttaaagaaa
     4801 aatataaaga agctaatgaa gttgtaggag atataataaa agtaactcca tcttcaaaag
     4861 ttgtaggaga cttagctatc tttatgacta aaaataaatt agataaagat aatataatag
     4921 aagaaggtaa aaatttatca ttcccagatt ctgttgtgga ttactgtaaa ggtatgattg
     4981 gtcaaccaga aggtggaata ccaaaagatt tacaagaggt agttctaaaa ggtgaagaag
     5041 ctataacagt aagaccaggt tcattattac cagcagaaga ttttgatgaa atagctaaat
     5101 atctaaatga aaagtatgat ataaatgcta atataagaaa tgttataagt tatgctttat
     5161 atccaaaagt atatgaagat tatatcaaac atctacaaca ttataatgat atatctaaac
     5221 ttgaaagtga tgtattcttc tatggattaa ataaaaatga agaatgtgaa gtagaaatag
     5281 aagaaggtaa ggtattaaca ataagattag ttgaaattgg tgaagttaag gaaaatggat
     5341 ttagaactat aggatttgag ttaaatggaa tggttagaga agtagaaata aaagataaga
     5401 atttctctgg aaaaattaat aatgttgaaa aagctgatat gaatgaccct cttcaaattg
     5461 gagcaagcat accaggaaaa gttataaaaa taatggttaa agaagaagat gaagtaaaag
     5521 caaatcaacc attaatcgtt atagaggcta tgaagatgga aactataata gttgctaaga
     5581 ctgatggagt aattaagtca atcaaagtaa aagaagatga tatggttgaa gataaacaat
     5641 tattaatgat aatgaagtaa tttaattaaa ataaattaaa aagcactctg aaatgtttaa
     5701 taaaaaatgt tttagagtgt ttttatttat tttaattaaa tatttgttaa aaaaaagagg
     5761 acaattacct ccagatgtag aaataaagct agtaaggaaa atgttatcta aaaattctaa
     5821 atatagtaaa tattttccat aatatttctt aggaaataac agcaaagata aaatacataa
     5881 atttaaaagg tgggtgctta tatgaaggtt tatgatagta aaatgttgag aaatgtagcg
     5941 gtattaggac atagcggatg tggaaaaaca aatctaatcg aaactatagc ttacacagca
     6001 aacactaata agatacctaa attaacagac aaggtaaata tgacttatag catgggatta
     6061 atacctatag agtataatga ttataagttt aacttattgg ataccccagg atattttgac
     6121 tttagcggag acgttgtgtc atctcttaga gcaagtgatg cagcaataat agtaatagat
     6181 gcaacagcgc ctattcaagt tggtacagag aaatcattag aactaactga gagtattcct
     6241 aagataatgt ttataaataa aatagataat gaaaaggcaa gatacaaaga tgcaatagca
     6301 atgttaagag aaaaatacaa taataagata gttcctatga taagtcctat atacaaagat
     6361 aaaaactttg taaagttaca taatgttttt gaaaacatag atgatttaga aggtgaattt
     6421 aaggaacaag ctatgagtgt taaagaagca ttaatggaac ttatagcaga aactgatgac
     6481 caaatattag ataaatattt taatggagaa gaactaacta cagaagagat acaaaaaggt
     6541 attattatag gtatacaaag aggtgatatt atacctgtaa tatgtggttc aactataaat
     6601 aatataggca caaaggaaat attagataca atatcaagtt atttagaacc tatctttaca
     6661 gaggaaagca aaccatttag gggattagta tttaaaacta tggttgaccc atttgttgga
     6721 aagatgtcat atataaaaat tactgagggt gtactttcta aggataaaga tgtttttaat
     6781 ataaataaaa atgtaaaaga aaaaatagct aatatatata cattgagaaa tagtgaatta
     6841 gtagaaatag aaaaagctaa agctggtgat atagtagtta taactaaagt taattctcta
     6901 aaaacaggag acactatatc tgcagataaa gatgcagaag ctttagaaaa gatagatttt
     6961 cctaaaccac aaatatatta tgcagtaact cctaagaata aaggtgatga agaaaaagta
     7021 gcatctgtat taaataaact agtagaagag gaccctacat tacattggta tagaaataca
     7081 gagacaaaac aagcactttt aggaggtcaa ggagaacttc atataaaaac aattaaaaat
     7141 aaaatgaaag ataagtttgg tgttgatgtt gaattgaatg accttaaagt tccttataga
     7201 gaaactataa aaggaacagc tgatgtacaa ggaaaacata aaaagcaatc aggtggtcat
     7261 ggtcaatatg gagacgtaaa aataagattt gaaagatgtg aatctgattt tgaatttaca
     7321 gaagaaatat ttggtggttc tgtaccaaaa caatatatac cagcagttga aaaaggttta
     7381 aaagactcta tgcaaaaagg tatattagca ggatatcctg ttacaaacat aaaagctacg
     7441 ctttatgatg gttcatacca tgatgtagac tcttctgaaa tggcctttaa aatggcagca
     7501 agtgcagcct ttaaaaaagg tatggaagaa gcacacccaa tactactaga acctataatg
     7561 aaacttaaga taactgttcc agaagaatat atgggagatg tcatgggtga tataaataag
     7621 agaagaggaa aaatatttgg aatggaacca gatgacaaag ggaaacaaat aatatttgca
     7681 gaagctccac aagcagagac atttaaatat gcaatagatt taagagcaat gacacaaggt
     7741 agaggatact ttgaaatgga attagagaga tatggagagg ttccatcaca gtttgcagaa
     7801 aaaataattg ggctagctac tgcaaagtaa tgaacaaaat aaatagaaaa ataattaata
     7861 tatattatta aaaatatttt tagggtttta actaggtata ggtttatgtt aggtaaactt
     7921 atacctagtt tttatacatt tttgatgaat aaaaaaatat ataatacttt cttaaatatt
     7981 ttaataaaaa gaaagtattt ttttattatt atttttacaa atgtttagta ataaagatga
     8041 gaaggtatat ttaaaatata aagtatttaa agttctgaaa tctaatcatg aagcaaaaaa
     8101 ttagcatttg gttatcaata aatataataa ataaaaactc ataattaatg aaagaataaa
     8161 ttcatatcta aatttctata aaaaatttaa atttatacaa tttagggctt taaaaattta
     8221 aataataggt gtaaaataat agtcaaagaa agtcaaaaat aaaaaggtgt gtggtgatat
     8281 taatggcaac tatgacagat ataattgaaa aatttattaa agatttgatg gaagaagata
     8341 atagcataca aattcaaaga aatgaactag caaacttgtt tagttgtgca ccatcacaaa
     8401 taaattatgt cttaacaaca agatttacaa tagatagagg atattacatt gaaagtaaaa
     8461 aaggtggcgg aggatatgtt caaatagaaa aaatacgaaa aagtaaagat gggcatatta
     8521 gagaactact aaatgaaaaa ataggaagtc agatatccta taaaaaagca aaagaattat
     8581 tagaaggttt aaaagagtcg gatttgatta acgaaagaga attaaaatta atattatatg
     8641 caatagatga taaatcattg tgtatgccaa tatatgaatt aaaagagaag gtaaggtcta
     8701 atattttaaa gaatataata ataggattat ttagtataga ggagtgataa tttatgctat
     8761 gtcaaaaatg caataagaat aaagcatctg tatattataa taagatagtc aatggagaaa
     8821 aaacagagat gtatttatgt agtgagtgtg caaaagagaa tacagaaatg aattttaact
     8881 tagatatgcc tttttcaatg atggatatat tttctaattt aggttttcaa cctaaaaaag
     8941 aacttgagga aaagctagtt tgtcctaaat gcaatacaac atatagtgag tttaagaata
     9001 atgggagatt tggatgtagt gaatgttata atgtatttag tagtcaagta aatccaatgc
     9061 ttcaaaatat acatgggcat atagaacata caggaaaagc acctaaaaaa tctttttata
     9121 agataagtgt agaaaatgag attaaagaac taaaagaaga tttagataga gctataaaaa
     9181 atgaagagta tgaattagca gctcaattta gagataaaat taaatattta aaaggttcta
     9241 ttgactaaga ttggagtgat attatgaaag agaacatagt catgaaatca agagttaggc
     9301 tagctagaaa tttaaataac tatccatttc caaataaatt agataaagaa tgtgccatgg
     9361 aaataataga aaaagtaaaa aatgcgttta ttaattctaa cttagaacaa aaagaagaat
     9421 ttgatttcta taaaattgaa gatttagacc aatctaaaaa aatgcttatg gttgaagaac
     9481 atataataag cccagattta gcagaaaatg ataaaagtgc agttatagta aaaaaagata
     9541 aaactataag tataatgata aatgaagaag accatataag gatacaaact atatgtgatg
     9601 atttaaactt agaatatgca tatagtgtag caaatgaaat agatgatttg ttagaatcaa
     9661 gtttagaata tgcctttaac acaaagctag gttatctaac atcttgtcca actaatacag
     9721 gaacaggaat gagagcttct gtaatgatgc atttaccagc attaagtcaa ctaggctata
     9781 tggatgaact ttataaaatt tcatcacaaa taggtatagc aattagaggg atatatggag
     9841 aacgaacaga agcattggga aatatatatc aaatatctaa tcaacttaca cttggaagaa
     9901 cagagtctaa tattatagaa aatgtaagtg gacttacaaa agatgcaatt tcaaaagaaa
     9961 taaaagctag agaaatattg caaaaaaaat taggtataaa actagaagat aaaatattta
    10021 gatcgatagg gacacttgaa aattcaagag taatgagtag cgcagaggca atgagccatc
    10081 tatcaaatat aaaaatggga atagaaatga actatataga taaactagat ttaagggcta
    10141 tagaacaact tatgataggt atacaaccag cgcatcagtc aataatgtat aagagtgatg
    10201 atgttgagaa tagagatata aatagagcaa catatattag agaaactttg gaaaaattaa
    10261 gaggagggat gaattgtgaa cttcaataga tttacacaaa gagctaaaaa ggcaattgat
    10321 ttagcgtttg aatctgctaa aagtctagga cacaatattg tcggaagtga acatatactt
    10381 ttaggtcttt taagagaaga agaaggtata gctgctaaag ttctaagtaa agttggattt
    10441 acagaagctt atttagaagg caaaatagtt gatatggaag gtaagggaga agaaatctca
    10501 gaagatatag tattaagtcc aagaagtaaa caaatacttg aattatcagg aatgtttgca
    10561 aataaattaa aaacaaatta tattgggact gagcatatat tattagcaat tattcaagaa
    10621 ggtgaaggaa tagctaataa gattttaaat tatgctggag taaatgatag gactttagcc
    10681 caattaacaa ttgatatgat gggtattagt gataaaaatc aatacaaagc agaaaatagt
    10741 tacacgggca accagaatca agcagaatct aaagtacttg ataagtatgg aagaaatctt
    10801 acactatatg caaaacagaa taaaatagac cctgtaatag gtagagaaaa agaaatacaa
    10861 agagtaatac aaatattaag tagaagaact aaaaacaatc cagtgttgat aggagaccca
    10921 ggtgtaggga aaacagccat agctgaaggt ctggctacaa atatagcctt aggaaatgtt
    10981 ccagaaacac taaaaaacaa aactttatac tctttagaga tgggttcatt attggctggg
    11041 gctaagtata gaggagaatt tgaagaaaga attaaagaag ttgtagatga agttgttaaa
    11101 aatggaaaca taatcttatt tatagatgag atgcacacaa taataggggc tgggtctact
    11161 ggagaaggct ctatagatgc ttcaaatata ttaaagccag ccttagcaag aggagaaata
    11221 caagttatag gtgcaactac aattgatgaa tatagaaagc atgttgaaaa agattctgct
    11281 ctagaaagaa gattccaacc agttatggta gatgaaccaa ctaaagagga ctcaataaaa
    11341 atattagaag gattaagaga taaatatgaa gctcatcata aagttaaaat aactgatgat
    11401 gctataaagg cagctgtaga attatcaact agatatatat cagacagata tctgccagat
    11461 aaagctatag acttgattga tgaagctgca tcaaaagtaa gattaaaaga aaatacacct
    11521 ccttcagaaa taaaaaaatt agaactagaa atagaaaata tagataaaga aaaagaagaa
    11581 gcagtaagat gtcaagactt tgagaaagca gccaaaataa gagatgaaca aggtctactt
    11641 aaaaaacaat tagaagatgt tagagaaaga tggaacaagt catctaaaca ttcagattta
    11701 gttgatggag aagttattgc tgaagtagtg ggcttatgga caggaatacc agttaataaa
    11761 attcttgaag aagaggctga tagacttttg agacttgagg aaatactgca caatagagtt
    11821 ataggtcaag aacaagcagt aaaatctatt tcaaaggcaa tcagaaggtc aagagcaggt
    11881 cttaaagacc ctaatagacc aattggttca tttttatttt taggtccaac aggagtaggt
    11941 aaaacagaat tatctaaggc attagcagaa gtgcaatttg gagatgaaaa tcaaataatt
    12001 agaatagata tgtctgaata tatggaaaaa catgctgtgt caagaatgat aggttcacct
    12061 ccaggttatg taggtcatga tgaaggtggt caattaactg aaaaagtaag aagaaatcca
    12121 tattcagtta tattatttga tgagatagaa aaagctcatc cagatgtatt taatattctg
    12181 ttacaaattc tagatgatgg tagactaact gattcaaaag gaagaactgt agattttaag
    12241 aatactattg taataatgac atcaaatgtt ggagcatcta caattggtag acaaaaaact
    12301 ttaggattta gtatagctaa aggagacgaa gaagaaaaat ctcaatatga aaaaatgaaa
    12361 gaaaatataa tgggtgaatt aaaacaaaga ttcagaccag agtttttaaa cagaatagat
    12421 gatataattg ttttccactc actaaatgaa aatcatatat caaaaatagt acttttaatg
    12481 gcagcgaaac tacaagagag attaaaagaa atggatataa aattagaaat gagtgatgag
    12541 gctgttaaat taatttctaa atctggattt gacttagaat atggagcaag acctcttaaa
    12601 agagctttac aaaaagagtt ggaagatgag ctatctgaag caatcttaaa aggtaatgtg
    12661 aaaaagggaa gtaatgtagt agcaaaagtc aaagatgaaa aaatagtttt tgaaactaaa
    12721 taatttaata gagttgcatt ttaaaatatt gcaaatataa gttttataat ctaaacaaaa
    12781 ttttaagggc aatgaatcta taataattca ttgtccttaa ttattttatt taatctttac
    12841 atattgtctt tcagatatgc taaaattata gtatagaata aaaaattaag gatgataaaa
    12901 gtatggcaaa aataaaaaca aaatatgtat gtcaatcttg cggatatgaa acagctaaat
    12961 ggcttggtaa atgtccagaa tgtacaaaat ggaatacatt tgtagaagaa atagaccaaa
    13021 aaagcaccaa aaaagaggtc tttataatag ataaatcttc atctaaacca gtcagtataa
    13081 actcaataga aagtaaagaa gaagagcggt ttacaacaga tataaatgag ttagatagag
    13141 tgcttggagg aggtatagtt aaaggctctt tagtgcttgt tggtggtgac cctggtatag
    13201 gtaaatcaac acttttaatc caagtatcta gtaatgttgc caatttagga aaaactgttt
    13261 tatatataac tggagaagaa tcagaatctc aaataaaaat gagagctaaa agattaggta
    13321 ttaactcaga aaatttatat atatttgctg aaaataattt aagtataatt gaatcttatt
    13381 tagaaagtgt aaatccagaa ttaataattc tagactcaat tcaaactgtc ttcagtccag
    13441 aaatatcctc ggcaccagga actgtcagcc aaattaaaga aggtacttca aaattcatga
    13501 aaatttctaa aaaaatggga atttcaacgt tcatagttgg gcatgttaca aaagaaggtt
    13561 cactagcagg accaaaatta ttagagcata tggttgatac tgttctatat tttgaaggag
    13621 aaagatataa tacttataga ttagtaagag ctgttaaaaa tcgatttggt tcaactaatg
    13681 aacttggagt atttgaaatg agggatttag gattagtaga acttgataat ccatctaaaa
    13741 ttttaatctc tgaaaaacca aaagatgtag caggttcagt aataatatct actgtagaag
    13801 gtacgagacc aatgttactt gaattgcaag cattagtttc tcctacaagt tttggtatac
    13861 caaaaagaac atctacagga gtcgattaca atagagtagg tatgttatta gcagtattag
    13921 aaaaacgtgt tggtttgcaa atacaaaatc aagatgtcta tataaacata gttggaggaa
    13981 taaagataaa tgaaccctca attgatttag ggatagccat ttctgtagca tctagtttta
    14041 gaaatatacc gatagatgaa gatatagctg ttacaggaga agtgggactt acaggagaag
    14101 ttagagcagt aagctttata gaaaagagaa tagctgagtg taaaaaactt ggatttaaaa
    14161 agatagtagt tcctagaagt aattatgatg ttgtaaaaga gaccaaaggc atagaaatat
    14221 ggccagtaga taacttaaga caagctataa atatagtact tgggaggaat caataaatat
    14281 ggagaatttt ctagataata aaaatatgct atatgcatta aaaatgatat ctcctggaac
    14341 tccacttaga ttaggtctaa acaatgtact aagagctaag actggtggat taattgtaat
    14401 tgcaacaaac gaagatgtaa tgaaaatagt agatggagga tttgctataa atgcagaata
    14461 ttcaccatca tatctatatg aattagctaa aatggatgga gctatagttt taagtggtga
    14521 tgtaaagaaa atattatttg ctaatgcaca acttatacct gactatttta tagaaacatc
    14581 agagacagga acaagacata gaacagcaga aagagtagca aaacaaactg gtgctatagt
    14641 cataggaatt tcacaaagaa gaaatgttat aacagtttat agaggaaatg agaagtatgt
    14701 agtcgaagat atatctaaga tatttactaa ggcaaatcag gctatacaaa ctctggaaaa
    14761 atataagaca gtattggacc aagctgtaac aaatttaaat gccttagagt ttaatgattt
    14821 ggtaactatt tatgatgttg cattagtcat gcaaaagatg gaaatggtaa tgagagttac
    14881 aagtataatt gaaaaatatg tgatagaatt gggtgatgaa ggaactttag taagtatgca
    14941 attagaagaa ttaatgggta caaccagaat agaccagaaa ttaatattca aagattataa
    15001 taaagaaaac acagaaataa aagaacttat gaaaaaggtc aaaaatttaa attcagaaga
    15061 actaatagaa ttggtcaata tggcaaaact attagggtat agtggttttt cagaaagtat
    15121 ggatatgcct ataaaaacaa gaggttatag gattcttagc aaaatacata gactaccaac
    15181 agcaataata gaaaacttag taaattattt tgaaaacttt caacaaattt tagatgcatc
    15241 tattgaagaa ttagatgagg ttgaaggaat aggtgaaata agagcaacat atataaaaaa
    15301 tggactcata aaaatgaaac aattagtctt attagataga cacatatgat gaattttaaa
    15361 tgaattttac tacttttttc ttgaatataa tatacacttt ggtctataat agataagtat
    15421 aactaggggg tgaagcattg ataaggaaag taacaagaat attgtttatt ttacttggat
    15481 ttacaatagg tataacaacc tatttaacat taatgaaaga ttttgaaata ttaacatttg
    15541 gaaaagaaac atatggttat atcgcagctg tagtagcagg tataataata gccattttag
    15601 gatatcttat agaaccatgg gttgtaaata aagtaaaaga aattgctaaa atagtggata
    15661 aagaattgtc aaaatatcct cagactgata tattgttagg gtctatgggt cttatagtag
    15721 gatttgttat tgcgtattta ttaagtggat tagtaaatag aataccaata gtaggtggaa
    15781 tactatcctt actattatat ttattcctag gatatcttgg aatgaaagtt gcgcttaaaa
    15841 gtaaaaatga tttatttaat attggaaaac taggaagatt agcaaatcct attaaggata
    15901 aagataagga taaagaaaat aaaaaagaag taaaagccat tcctccaaaa gtattagata
    15961 caagtgtaat aattgatgga agaatagctg atatttgtaa gactgggttt atagaaggaa
    16021 aacttattat tcctgctttt gttttggagg aactaagaca tattgcagat tcttcagatg
    16081 atttaaaaag agtaagaggt agaagaggtc tggatatatt aaatataatt cagaaagaat
    16141 taaatataga agttgaaata agtgagagag actttgatga tatagcagaa gttgatagta
    16201 aattattaaa gcttgctcag gttttaaatg gaaaagttgt tacaaatgat tataacttaa
    16261 ataaagttgc tcaattccaa ggtgttgaag tattaaatat aaatgagtta gctaatgcta
    16321 taaaaccagt tgctatacca ggtgaagata tggttgttca agtggttaaa gaaggaaaag
    16381 aggctcaaca aggtgttgca tatctagatg atggaactat gatagttgtt gatggaggaa
    16441 gaaaatatat gaatgagact ataaaagtac tcgttacttc tgttcttcaa actcctgcag
    16501 gtagaatgat atttgcaaaa cctaaaaatt aatatgttca aagaaaccta taatttgggc
    16561 tgtttatttt aaatagatgg tccaaattta tttatttata acgataatgt ttaatgtatt
    16621 cttaaagatg gggatttaaa tcagaaagca gggagaattt atgagaaaaa agattatatc
    16681 tttcttagca acatttatca taatattaac atcagcaagt cagtatagtt ttgcagatga
    16741 tatatcaaca cgtggaaaag taatatttat agatatgaat agaactagta tgagtaatat
    16801 gttaagaata aaatcattaa gagaagaact agacaataga gggtatattg gcttgatgaa
    16861 tataagaggc gataaaggaa gtgatgatag aaggtcatat gctagtatgg gtgctggtgg
    16921 tagagctaat gtggctaatg aagaagatat taattttgaa agctcgagta aggatagaaa
    16981 tatagttttt gaatcagcta caggaaaaag tgcaaaaggt ataaataatt taactataaa
    17041 taagtctata aatgaaaatt taaactttgg agagtatggt tctgtattag ggtcattagg
    17101 acaaagttta tctgataatg gattaaaagc atctgtattg ggtaattcag atataattga
    17161 aaatggtcaa cttataaaaa atagaaactt atgtctaact gcaatggatg aatatggaag
    17221 aatacctaat ggaaatgtag atactataaa taaaaaagac ttatctatgc cttatggaat
    17281 atcaactgat tatgataaat tgattgtaga gactaaagaa gcttacaaaa ataatgatgt
    17341 gatttttgtg gagcttggag acacatatag attagattta tataaaccaa atttaaatga
    17401 aaaaacatat gagagtatga aagataacat agaaaaaaat atagatatat atttaaaaaa
    17461 tatattttct atggttgaag aaaatgacac tgtctacata gcaagtgcat ttccaagtga
    17521 tttagattat aaaaataaaa gaagactttc gccaataata aaattaaatg gagaagggaa
    17581 aggtatatta tcatcttcaa ctactagaag agaaggtatt gtaacaaatt tagatgttgg
    17641 ggttgaaata ttagacaact ttaatataaa aaatcaaaat atggttggaa gaaaatatga
    17701 acttattaac agagatgata ataaagaatt tttgatggat gaatatcaaa agatagtatc
    17761 tatttcaagc ataaggtcta caatactgaa tggttttgta agtatagttt tcttgtcatg
    17821 gatagttgct atgattgcaa ttttatttag aaagcatata tcaaaaaatt ataaagaaac
    17881 aacatttttt atattaaagg aacttttaaa aataggaata gtaatgccac tgtcatttat
    17941 gataacacca ataatgaatt tcaaaacacc attagcaata tctttaggaa taattataat
    18001 aacacttact atatatctta taagtaaagt tttaataaag aacgatttaa aaaacatgct
    18061 gttttttact ggattaacca tagtaattat ggttattgat gctgggtttg gctcatattt
    18121 aatgaaaagc aatgttatga gttatgattg tataattgga gctagatatt atggagtagg
    18181 aaatgagtat caaggtgtgg caatcggtag tgcaatattt acatttgcaa ttttacttac
    18241 atataaaaat ataccaaagt ggtctataat agttttttct ttggttatct taattacaag
    18301 tgcatctcca attatgggag caaatgttgg aagtgctatt tctgaatgtg ttgcattttt
    18361 actatttata ctattgatat ataatgtaaa gatagatttc aaaaaaatcg tattattagg
    18421 tatagcagta ttatttgtat taggagtttt tgtagcaata gatatgattt tgggaagtaa
    18481 ttcacattta ggtatgtttg taaaagaaat ttactttaat ggaccaggag aaataataca
    18541 aacatttagt agaaagatag agatgaattt aaagctagct caaaccagtg catgggtaaa
    18601 tatactgtta actggaatag gtgtaatttt agttcttatg attaatcaga ttagatactt
    18661 taagcaactg atggatgagt atccaattgt atttaaagga tttatagcat caatagcagg
    18721 atgtttagta actcttttag tgaatgactc tgggattgtg tcatcagcta cagcctttat
    18781 ttatgtaatt gtacctatga taacattaag tataaatctc acagcattaa aagaataagt
    18841 actgtatgaa taatatgtaa atattaatac attaatttaa cttctttatt tacaaaataa
    18901 agaagaaagt ttataaaaaa taaattataa taaaaaagag tttacctcaa aattgattat
    18961 tctaatcaaa ttttaaggta aacttttttt attataaaga taaataacat ataacctcat
    19021 attttaggta gatttttttc ttatatgttt aggagtgcat ttaaattttt ccttaaaaat
    19081 tctgtaaaat aattttgtat tagtaaatcc atgagcttct aatatactgc ataaggtatc
    19141 atttgtgtta attaaatctt tataaatatg agaaatacgc acatcattta aatactctaa
    19201 gtaagtttgt cccatatact gtttaaattt tctacaaaaa tattctggtt gtaagtgtgc
    19261 taccttagcg attttgttaa tagaaatagg cattttgtaa ttaatctttg tatattctaa
    19321 aactggctca aattttgaca aatcaagtac tgtttttttc atatttttat tacctacaga
    19381 tattttaaag tttgtatata attcaaataa aagttcaaat aataagcttg taaagagcag
    19441 attagctgca ggaggagaac taagtttaat ttctctcatg ttttctaata taagtttaac
    19501 tttacttgaa ttttttttat agttattgtc attggcatta accttaaagt caaaatagca
    19561 atttttaaaa tcagggatat atttgtttag aaaagacaat ggtacttgca ataatataga
    19621 ggtattttga taaatacatc tagttgagtg aataattcca gaattaatga acatacactc
    19681 attagctttt aaattataag tgtaaccctc catgttaatt tgtaaatcac cagaagttat
    19741 ataaattatt tctaatgagt tatgccaatg atttgctaca taactaccac tatcctgaac
    19801 ctcccatgac taaagtcaca gggttcctgc ttcacagaat tttgcatact aaaataaatt
    19861 ctccacaggc tatccccgta gttcctacgg ttcttacata agttatttat tttgaattgt
    19921 tattagtctt aatccttctt ttaatatatt tatacttgca tttatatctc tatcgtgagt
    19981 ttcattacaa ctaggacaaa tccattctct tatatttaag tccttcactt cctcgttttt
    20041 atacccacat ttattgcata tttgtgaact tgcaaagaat ttacccacct ttacaatttg
    20101 tctaccatgc caattagcct tgtattctaa ttgacgaata aactctgacc atgacacatc
    20161 agaaattaag cgagatagtt tacgatttct aatcatattc tttacttgta aatcttctat
    20221 gcaaataata tcattctctt ttattaattt agtagatagt ttttgtagaa aatcatttct
    20281 ttgattagct atatgttctt gaagtcttgc aacttttaat cttgctttat ttctatttaa
    20341 actaccaatt gtttttctcg ataattctct ttgtaattta gcaagtttgt ttaatgactt
    20401 cttaagatac ttaggatttt ctataaattc tccacaactt gagatacaaa attctttaat
    20461 tcctaaatct aaacctatat gattattagt attttcaaat gcttcaatat ctacatcagt
    20521 acagcataat gatacataat atctaccact tggctcttta gatatagtag cattaagtat
    20581 tctacctt
//
LOCUS       DAFAZV010000062        20482 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFAZV010000062 DAFAZV010000000
VERSION     DAFAZV010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 20482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20482
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.062"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..440
                     /locus_tag="KOU88_003422"
     CDS             <1..440
                     /locus_tag="KOU88_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213257.1"
                     /translation="NATESQFKIRDYIKNINAGFALYERSAQDLLTKLMTHENKISQN
                     QKILLDEKFTLDDSIKNLSSIIENFSNDLQVKLDMMFENSLDIQDKLDVMFNNSFMND
                     EVPLDSEELFKDDVNNVFNPFSEEIYEIEDKEIKVIGEDELNE"
     gene            433..1065
                     /locus_tag="KOU88_003423"
     CDS             433..1065
                     /locus_tag="KOU88_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBK3213258.1"
                     /translation="MNNKYRRTVNREFEKSSFWPTFTDLLSTVLMVVILILFSSESIS
                     GSVEQDLAKNVNASVEETFKKSGIPVKVDKSNGQVTFGEKTMFDVDSDVLKPEAKEML
                     KMFVPKYIETIYKDYGDYISKIVIEGHTDDVGSYIYNLDLSQRRAYSVAKFIVGDEIG
                     DYKYKDKVTKHIIAIGRSKAELIKNGDNSVNRDASRRVELKYEININQNK"
     gene            1394..2551
                     /locus_tag="KOU88_003424"
     CDS             1394..2551
                     /locus_tag="KOU88_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3213259.1"
                     /translation="MIEISIKNKKNSKIKTLILLLIVSISIYLTGCTTSDNGNNQSNN
                     NDSLSSSISSDKNVKIHFIDTGNSDAILIQDGKTFTLIDGGDNDDEGLMVDYLNNQGV
                     KDIKYLIATHSHADHLGGLDSVVKNFNIENVFVSNGSAETKSYRDFINALANKGLSPS
                     VPLENNKFYLEDSYFEVLNTNGGDTTNEQSLVLVYTNGNDKVLFTGDAEEGTEKEILP
                     KLEKVDLLKVAHHGSRSSSSQEFLDKVNPEYAVLLVGKGNSYGHPHQETMNKLKKMGV
                     KVHRSDECSDIIFESTGDGVFTSCKDGSYNKGVREDGNSGKSNSNTSKNDSFKNKQNT
                     SNSEEIVYFTPKGKSYHSTKNCSGLSRSKKILSGTIAESKKNDPCDICYGK"
     gene            complement(2698..3333)
                     /gene="lexA"
                     /locus_tag="KOU88_003425"
     CDS             complement(2698..3333)
                     /gene="lexA"
                     /locus_tag="KOU88_003425"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBK3213260.1"
                     /translation="MYLDLTEKQVLILEFIKSQIILKGYPPAVREICTAVGLRSTSTV
                     HSHLNKLEKLGYIRKDPTKPRAIEVLERSKVNDVSGANQEIIELPLVGQITAGEPILA
                     QQNIEEYIPFPASLVKGSNNFVLRVKGESMINAGILDEDYVVVDKKNTALNSQIVVAL
                     INGESATVKRFFKEGNLIRLQPENDFMEPIMLNDSEVEIVGIVTGVFRVIK"
     gene            complement(3437..4564)
                     /locus_tag="KOU88_003426"
     CDS             complement(3437..4564)
                     /locus_tag="KOU88_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK3213261.1"
                     /translation="MNNDKKIIKVHNKSDKPDNIVIKENELIEKCLLLENKLPVFMKD
                     YFIYLKGSVAVSTRLAYLEDINFFCSYLIETKELTNADCVKDITEDDFNTIKSRDINL
                     FLGDYCSRYYKNTEKNTLIFENNNRALARKKSSISTLFKFLYRNSQIDNNITDGFNPI
                     KLPKPQPDAIKRLEIDEVAKMLESVETGEGLTEKEKVYWRKTKLRDKAILALFVTYGL
                     RLNELRELNISSFNFSRGEFKIYRKRGKEVLMPINHTCEHVIKDYLQNERTRDELLND
                     EEKDALFLSLQNKRITAKAIRTLVKKYTSIPLDTTRDNGYSPHKLRATAATSLIQTGF
                     SIYDVQNLLDHDNVTTTQLYAAHKKNVKRDIVKNFEWIEDD"
     gene            complement(4885..5730)
                     /locus_tag="KOU88_003427"
     CDS             complement(4885..5730)
                     /locus_tag="KOU88_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213262.1"
                     /translation="MIYIIEILKISVINIFCFIGIFIVFGLIFSITENLNNKFIFSSF
                     GKTGIIVTGAIGTFVHELSHLIMCLIFMHKINSVKFFRPIESKNDGILGYVSHSYKKD
                     NLYQSIGNFFIGIAPIIGGTIMIILIFKILLPDSYMKVTQNIDLKLYVSMINNLNING
                     FIHIILGDISNFIRIMLLTPSVYSLKYFIFMFLMYSISTHMSLSSADLKNSLNGLSFI
                     VIVIFVISSITYLFGFDNLNISSLIVKYNIFISFFMAIGFIFSIVTLIISYILSLVSP
                     FKNFS"
     gene            complement(5760..6131)
                     /locus_tag="KOU88_003428"
     CDS             complement(5760..6131)
                     /locus_tag="KOU88_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HBK3213263.1"
                     /translation="MKLKLLVEEYAVCRLNNDSKIPTWIDTEKFYSITRTDDELSVVC
                     LNNNIPSDVKSEKEWRILKILGPLDFSLVGILSKLSSLLADNKISIFAISTYDTDYIL
                     VKEKDIENACKILSCNGYEVE"
     gene            complement(6284..6544)
                     /locus_tag="KOU88_003429"
     CDS             complement(6284..6544)
                     /locus_tag="KOU88_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003866776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage V sporulation protein S"
                     /protein_id="HBK3213264.1"
                     /translation="MEVLKVSSKSNPNSVAGALAGVLRERGVAEIQAIGAGALNQAIK
                     SIAIARGFVAPSGMDLVCIPAFTDIEIEGDKKTAIKLIIEPR"
     gene            complement(6733..7677)
                     /locus_tag="KOU88_003430"
     CDS             complement(6733..7677)
                     /locus_tag="KOU88_003430"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HBK3213265.1"
                     /translation="MIENNSEKIKVLENDIKQLITISKANNIDLSDKINSLNEKLEKL
                     KEDAFSHLSAYEKVTLSRDIKRPTTLEYIEHICSNFLELHGDRLFKDDPSMVGGIGQI
                     GKFNVTIVGHQKGRDTKENIKRNFGMPHPEGYRKALRLMKQAEKFNRPIITFIDTSGA
                     FCGLEAEERGQGEAIARNLLEMSKLSVPVITFVIGEGGSGGALGIGVGNDVCMLEHSV
                     YSVISPEGLSSILFKDSSKAKEACDVMKLTSNDLYDLKIIDKIIKEPLGGAQKDVEAV
                     SKEIKAYILERLNHYKDMDKEEIIAQRYKKFRNIGKCL"
     gene            complement(7698..8552)
                     /locus_tag="KOU88_003431"
     CDS             complement(7698..8552)
                     /locus_tag="KOU88_003431"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBK3213266.1"
                     /translation="MIKKFLSSKESKYVTISLDDNFKKNSVDDKFWTYCKGCDSHVFR
                     KDIEENSFVCPKCSRHYGLRARKRINLLIDKGTFMEFNSDVEFQNPLNFPKYKEKVDS
                     YKEKTKESEAVVTGYGRINGIKTVICVMNPDFMMGSMGSIVGEKITYSIEYAAENNLP
                     IIICSASGGARMQEGMVSLMQMAKTSQALSKLEEKSLPYISVLTDPTTGGVTASFAML
                     GDIIISEPNTLIGFAGPRVIEQTINQKLPEGFQTSEFLLEKGFIDMIVDRRKMKEVLY
                     QILAMHKK"
     gene            complement(8567..9928)
                     /gene="accC"
                     /locus_tag="KOU88_003432"
     CDS             complement(8567..9928)
                     /gene="accC"
                     /locus_tag="KOU88_003432"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBK3213267.1"
                     /translation="MIKKILVANRGDIAVRIIRTCKELGIKTVAIYSEIDKDCFHRYI
                     ADESICIGPNNISKSYNNIENIIYLALKLKCDAIHPGFGFLSENPEFAKQCEDNNIIF
                     IGPTREQMILMGDKSRARETMMELNIPVVPGSESVLKTKEEALEVAREIGYPVMIKAS
                     SGGGGKGMRIVRKEEELFSNFDMASSEALAAFSNSDLYMEKFIENPRHIEVQVFGDKH
                     SNAIHLGDRDCSMQRRNQKVIEESLSPYLSDEERQKLHKIAVDIVKGVGYIGAGTIEF
                     IVDKDKNFYFIEMNTRIQVEHPVTEMVTNLDLIKLQISIANGDKIPFKQEDITFRGHA
                     IECRINAEDSSKNFAPSPGKIESLNLPGGFGVRFDTFVYAGYTIPPLYDSMIGKLICW
                     AETREECISRIYRALDEIIVEGINTNVEFQKALVTSEEFREDTHHTKFIEDVFMKKEF
                     ATL"
     gene            complement(9944..10396)
                     /gene="accB"
                     /locus_tag="KOU88_003433"
     CDS             complement(9944..10396)
                     /gene="accB"
                     /locus_tag="KOU88_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBK3213268.1"
                     /translation="MNINEIKELLKAIDSTNLEYVKLESSDLRLEVSKKAQSTSSPVL
                     SVQQESVVDLSLEKPVVNDTPVTSNENLSVVVAPLMGTFYDSPSPDADSFVKVGDVVE
                     EGDTLCILEAMKLMNEITSEIKGEIIEVLVSNEELVEYNQPLFKIKPL"
     gene            complement(10666..11112)
                     /locus_tag="KOU88_003434"
     CDS             complement(10666..11112)
                     /locus_tag="KOU88_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213269.1"
                     /translation="MESKFFNWYTQSLGGTFGIISCICAYLNGYMFVYTNSASKYFES
                     IGFLGIISSYTLLPLCMLTLIFGVIYSYTPETSDKSIFNIPFFTLNKRLILITVVFGF
                     IGARVYFIIPAILITFNLYSNVLIAKLKYILCKNKENDTNLKESEV"
     gene            11387..11665
                     /locus_tag="KOU88_003435"
     CDS             11387..11665
                     /locus_tag="KOU88_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213270.1"
                     /translation="MVDTLEFGLKILFFILSIIWMGKIMILRTDKQIVINPLLIGISA
                     ILVMLHTSQSNIEFFGLDVQYIRIVLYIIYSLIILIGIWATNRRNGIF"
     gene            complement(11794..12540)
                     /locus_tag="KOU88_003436"
     CDS             complement(11794..12540)
                     /locus_tag="KOU88_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213271.1"
                     /translation="MWEGTMNLANLIPFIISAAALSPINSNDKVLSENQLKDIFPDAN
                     LRAVVKRYINPDEMTISNIKALDGEFYATGESISNLKGISYLENVDNFIFWNNNIKEV
                     PKEALSLKDMDSINLANNYLIDDDVVNSLSHNGVDVNCDLNFIDTKDNQYKLDSKYHN
                     VDIAKGESIDLRKIITKKIDSYYKYWEVTDNLPKDLNFIVSVSDKSVLSCEDMIIKGN
                     KTGKAVVKVILSDKNDLNTSQEVLITVNVK"
     gene            complement(12669..13313)
                     /gene="trmB"
                     /locus_tag="KOU88_003437"
     CDS             complement(12669..13313)
                     /gene="trmB"
                     /locus_tag="KOU88_003437"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBK3213272.1"
                     /translation="MRRRRKKGADEKLLSYTKYVLRDDIDKLKGKWNLKFRNDNPIHV
                     EFGTGKGKFITTLAKQNPDINYIAMELKEEVLLKAVEKADASNLNNILFLWGDVSNIL
                     DYFEAKELSRIYINFCDPWPKNRWSKRRLTHSGFLEMYNRVLEDDGEIHFKTDNEKLF
                     EFSLNEIAANNWLLKNISLDLGNSEYENNVTTEYEDKFMSQGMRIFRCEAKKRN"
     gene            complement(13451..13771)
                     /locus_tag="KOU88_003438"
     CDS             complement(13451..13771)
                     /locus_tag="KOU88_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein HesB"
                     /protein_id="HBK3213273.1"
                     /translation="MKITLPETAIDTLKSILKDNQDKPNNIRVYFAGVGCGGPSFGLA
                     LDEKKEDDLTYEVGELQFVMSSDEYSQYGDIIIEDTGFGFRVIPENMKDQGGGGCSGC
                     SGCH"
     gene            complement(14232..14471)
                     /locus_tag="KOU88_003439"
                     /pseudo
     CDS             complement(14232..14471)
                     /locus_tag="KOU88_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435328.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
     gene            complement(14508..14963)
                     /locus_tag="KOU88_003440"
     CDS             complement(14508..14963)
                     /locus_tag="KOU88_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBK3213274.1"
                     /translation="MKFGGVLLIVKDINKSKKFFEDVMEQKITLDLGEHVSFENGFGL
                     QSNYKAIIGYDLPIYQQSNNFQLYFEVNDIKQWESKINRIGNIEFLHYIKEYPWGQRT
                     FRFYDFDKNIIEISESMESVIKRLLKQGLALEEISKRTMYPVEFIIQFQ"
     gene            complement(15001..15834)
                     /locus_tag="KOU88_003441"
     CDS             complement(15001..15834)
                     /locus_tag="KOU88_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213275.1"
                     /translation="MLKKESIHFINKNRSLIVCEDNFVYLLPCIQLRNWISNFTISFP
                     NQTIISDNYTIIPHGSVTLVFFYDATGLHSLLFGPTTKPKTVGNIANRCDVILIIEFQ
                     PAGFFPLIGIQQSELIDKVVPFSIINTSLDLEIKKIFNESLSIDKLILKLEELLISNI
                     KIEYSYEFILAIQLIIQNSGNISSQEISKKVFYSSRHLNRLFNQYLGLSMKSFSRLVR
                     INKSIKLLNNNKTSLMSICNELGFYDIPHFIKDFKIVCGITPQKYRANMSDFYSEIAK
                     F"
     gene            complement(16108..16794)
                     /locus_tag="KOU88_003442"
     CDS             complement(16108..16794)
                     /locus_tag="KOU88_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213276.1"
                     /translation="MKITHNSLAVEAKNIIKEYKIGNTTTRVLKEVSLQVMKGEFVSI
                     MGQSGSGKSTLLYILGGLDTPTSGKVYMNGADISHFNDEKMSIIRRRNIGFVFQFYNL
                     IPNLNVEENIMLPLLLDGKNLKDYKNQLDEILDIVGLTDRRKHTPRELSGGQQQRVAI
                     ARALIGKPEILFADEPTGNLDSKTGIEIIDLLNKINRDNGQTIIMVTHSPEAAKSSSR
                     TITVSDGLIV"
     gene            complement(16809..19286)
                     /locus_tag="KOU88_003443"
     CDS             complement(16809..19286)
                     /locus_tag="KOU88_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBK3213277.1"
                     /translation="MKIILKYIFTNIKERKIRTAVMLLSIVLSTVLLFVSFSIGLSYE
                     SAQRKMAKGMYGTATISVQSKNPDILTNLEDIPDLNTIKSKVGVLESSAIYNKGGYYE
                     EFSLISADLSQLNKINKPRLENGDSITDFSGDKIILPNRFTSKYKIKKGDSITLQIYG
                     KSYTFQVSDIASYDTVFLRNTRGVNALLPKETLSKIINKGSGYTRVLIESEEEITENL
                     VNKLSEELSTEKYMVSNTINETKIISDARQKTMPFFLISFFALTLSIFIIYSSYKVIT
                     LERLPFIGTFRSIGANEKTVTRILMLESILYGSIGGLIAIPIGVVVLNLMLHGLGNSL
                     EQGISIPVVISPIGVIISVIVAIIVSSFSAYIPVKKASHLPIKNIVLGTVEEKNVSNR
                     SILFIGSIMFILSILLPRIYPENTLYLAGGFSLLGLIVATIVLIPLITDIMSIVFEFV
                     YKNILGNEGKLAARNMKNNKNIIQNITLLFISISAVIAISVVGNFVKTYITDVFRDAE
                     LQGFADGKMNEEFIEDVRHMDGIKKILPLYVMNNEISGNGVTLSRLEGTDNIKLYNSM
                     FGINYTNFEIKKQVIETFNDKRSVILNEDTLKKVGLSIGDTITLSNDKYDFSYKIIGS
                     FKSRANDVEAVIPSHYAVNDFDKTNYGFLVYTAVNPDAVMIQIRYLFGDTYNWSRTVE
                     EFNNDSLNTISSFLSPMNKMTYFIFLLATVGIINNLLINYIQKRRSIAMYKSIGLSNK
                     QNIKVTLIEGFTSGLLGAVIGIVISILEIQTIFIVAGPKISMKPDLDFKTFIIVGLLG
                     IIVTLIGSIVPIIKGKKMKLIEEIKFE"
     gene            complement(19505..>20482)
                     /locus_tag="KOU88_003444"
     CDS             complement(19505..>20482)
                     /locus_tag="KOU88_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3213278.1"
                     /translation="IYFPLNISKVNMFFDGGKFIGGKSIVFSIIGIIFLIILVSGIAY
                     GYWVTKCISNITSAVSDISKRSYLPVNIKGVFADIYNSLNILNEEIHRSDEIQNKTDI
                     MREEWISNITHDLKTPLSPIKGYAELLTDSSTNYSPEKVYKYASIMLKNIEYTNTLIN
                     DLKLTYQLKNGIIPLNKNNYDLVRFLKELSIDILNYPEYESNIVEFKSNIDNINFDFD
                     CTLLKRAFSNLIVNAFTYGDKNTKVCVHITLNERIEIIISDNGKGMSREEASNLFNRY
                     YRGSNTKQKIEGTGLGLAITKQIIEVHGGNISVESIPGLGSSFYITFPI"
BASE COUNT         7160 a         3175 c         2347 g         7800 t
ORIGIN      
        1 acaatgccac tgaaagccaa ttcaaaatta gagattatat aaaaaatata aatgcaggat
       61 ttgctctata tgaaagaagt gctcaagact tattaactaa attaatgacc catgaaaata
      121 aaatctctca aaatcaaaaa atccttttag atgaaaagtt taccttagat gactcaataa
      181 aaaatctctc aagtattatt gaaaactttt ctaatgacct acaagttaaa ctggatatga
      241 tgtttgaaaa ttctttagat attcaagata agttagatgt tatgtttaat aactctttta
      301 tgaatgatga agttcctctt gatagtgaag aattatttaa ggatgatgtt aataatgtat
      361 ttaatccttt tagtgaagaa atttatgaga tagaggataa agaaataaag gtcataggtg
      421 aggatgagtt aaatgaataa taaatataga agaactgtta acagagaatt tgaaaagagt
      481 agcttttggc caacatttac agatttatta tctactgtat tgatggttgt aattcttatc
      541 ttatttagct cagaaagtat ttcaggttct gttgaacaag atttagctaa gaatgtcaat
      601 gcttctgttg aagaaacttt taaaaaaagt ggaatacctg tgaaggtaga taaatctaat
      661 gggcaagtaa cttttggtga aaaaaccatg tttgatgtag atagtgatgt tttaaaacca
      721 gaggctaaag aaatgctaaa aatgtttgtt ccaaagtaca tagagactat ttataaagat
      781 tatggtgact atatatccaa aatagttata gaaggtcata cagatgatgt gggaagttat
      841 atatacaact tagatttatc gcaaagaaga gcatatagcg ttgctaaatt tatagtggga
      901 gatgaaatag gtgactataa atacaaagat aaagtgacta agcatattat tgcaatagga
      961 aggtcaaaag ctgaactcat caaaaatggt gacaatagcg tgaatagaga tgcatctaga
     1021 agagtagaac taaaatacga aataaatatt aatcaaaata aataattaaa tttttataaa
     1081 aaaaaagaag gcagttggtg tgagctttaa gccttcttta aggaaaaagt ttatttattt
     1141 ttgttgatac ttaacatatt atagttttta gaagcagttt gcaatatatt aaacgtaaat
     1201 ggtcgtttaa aatgcataac tggatactac tgatgtaaaa tatttcattt tatataatat
     1261 aaaaattata cagtgtcaat tttctatatt attgtactat aatctattat ttaaaatatt
     1321 atgtaaaaaa atatcataaa aacgcatatc atgttataat tactagagta ttatgaatat
     1381 ggaggcgtag tttgtgatag aaataagtat aaaaaataaa aaaaattcta aaattaaaac
     1441 tttgatactt ttattgatag tatctatatc gatttattta actggttgta ctacatcaga
     1501 taatggaaat aatcaatcaa ataataatga ttctttgtct agtagtatat caagtgataa
     1561 gaatgtaaaa attcatttta ttgacactgg aaatagtgat gcaatattga ttcaagatgg
     1621 taaaactttt acattgatag atgggggaga taatgatgat gagggattaa tggtagatta
     1681 cctaaacaat caaggtgtaa aagatattaa atatcttata gctacccatt ctcatgcaga
     1741 ccatttaggt ggacttgatt ctgttgtcaa aaactttaat atagaaaatg tttttgtatc
     1801 gaatggttca gcagaaacaa agagttatag ggactttata aatgctttag caaataaggg
     1861 tttatcccca agtgtaccgc ttgaaaataa taagttctat ttagaagatt cttattttga
     1921 agttctaaat acaaatgggg gagatactac taatgaacaa tctctagtcc ttgtatatac
     1981 taatgggaat gataaagttt tatttacagg tgatgctgaa gaaggtaccg aaaaagaaat
     2041 actacctaag cttgagaaag tagacctttt aaaagtagct catcatggtt ctcgtagtag
     2101 ttcatctcaa gagtttttag ataaagtaaa tcctgaatat gcggttcttt tagtaggcaa
     2161 gggtaattca tatggtcatc cacatcagga gacaatgaat aaattaaaaa aaatgggagt
     2221 aaaagtacat agaagtgatg agtgttcaga tataatattt gaatcaacag gtgatggagt
     2281 atttacaagt tgtaaagatg gaagttataa taaaggcgtt agagaagatg gaaactctgg
     2341 aaaatcaaac agtaatacaa gtaaaaatga ttcttttaaa aataaacaaa atacatccaa
     2401 ttcagaagaa atagtgtatt ttactccaaa aggtaagagt tatcactcta caaaaaattg
     2461 tagtgggctt tcaagaagta aaaaaatatt atcaggcaca attgcagaaa gtaagaaaaa
     2521 tgacccatgt gatatatgtt atggaaaata acaaaaaaac aaccaattta tctataaagc
     2581 ttctgaactt taaatcattc aaaaaataaa ataaatgcat aaaaaaataa gctataatca
     2641 atagataaca cattttatct atacgaatag cttatttttt taagtatttt ttaatagcta
     2701 tttaataact ctaaatacac cagttacaat acctacaatt tcaacttctg agtcattgag
     2761 cataattggt tccataaaat cattttctgg ctgaagtctt attaaatttc cttctttaaa
     2821 aaacctctta actgtagcag attcaccatt tataagtgca actactatct gagaatttaa
     2881 ggctgtattt tttttgtcta ctacaacgta atcttcatct aaaattcctg cattaatcat
     2941 actttcgcct tttactctta atacaaaatt gttactgccc tttactaaac tggcagggaa
     3001 tggaatgtat tcctctatgt tttgttgagc taaaatgggt tctccagctg ttatttgacc
     3061 tactaaagga agctctatta tttcttgatt agctccagaa acatcattta ctttactacg
     3121 ttctaaaact tcaatagctc ttggtttagt agggtccttt cttatgtatc ccagtttttc
     3181 aagtttattt agatgagagt gcacagttga agtagatctt aaccctacag cagtacatat
     3241 ttctcttaca gcaggtggat aaccttttaa tatgatttga gactttataa attccaatat
     3301 caagacttgc ttttcagtta gatctaaata cataacatca ctcatttcca aacatatttt
     3361 gtttttattt ccatacactt tatattttta attataacat aatccattta tatctgcaaa
     3421 catttgttcc tgatttttaa tcgtcctcaa tccattcaaa attcttgact atatcacgtt
     3481 ttacattttt cttatgagct gcataaagct gagtagttgt gacattatca tggtcaagta
     3541 agttttgaac atcatatata gaaaatcctg tttggattag agaagttgca gccgttgctc
     3601 ttaatttatg gggactatat ccattgtctc tagtagtatc aagtggaata gatgtatatt
     3661 tttttaccag tgttcttata gcctttgctg taattctctt attttgaaga gacaaaaata
     3721 aagcatcttt ttcttcatca tttaatagtt catctcttgt tctttcgttt tgcaaataat
     3781 cttttattac atgttcacaa gtatgattta taggcattaa aacttctttc ccacgttttc
     3841 tatatatttt aaattcacct cttgaaaaat taaaagagga gatattgagt tctctaagct
     3901 catttaatct aagcccgtat gtaacaaata atgctagtat agctttgtca cgtaatttag
     3961 tttttctcca atataccttt tctttctctg taagcccttc acctgtttct actgattcaa
     4021 gcatcttagc aacttcatct atctcaaggc gcttaatagc atctggctga ggtttaggaa
     4081 gttttattgg attaaatcca tcagttatat tattatctat ctgagagttt ctgtataaga
     4141 atttaaatag agtagagatg gatgattttt ttcttgctaa agctctattg ttattttcaa
     4201 aaatcaatgt gtttttttct gtatttttgt aatatctact gcaataatca cctaagaata
     4261 aatttatatc tcttgatttt attgtattaa aatcatcttc tgtaatatct tttacacaat
     4321 ctgcatttgt taattctttg gtttcaatca aatatgaaca aaaaaaatta atatcttcta
     4381 aataagcaag tcgtgtagaa actgcaacag aaccttttaa atatataaaa taatccttca
     4441 taaatacagg aagtttattt tccaaaagta gacatttttc tatgagttca ttttctttga
     4501 taacaatatt atcaggttta tctgatttat tatgtacttt tataattttc ttatcattat
     4561 tcaaaattaa acctcctaaa actaaaatat aaatctttta tattattttt tgatatttat
     4621 accaagtgag tataaatatt taatttaatc attttttaca tttttaagag attagcagtg
     4681 ctttagatga aattatcact aactattccc taaatccaca tttaaagact agttgaattt
     4741 aagtactctt ttttatttct caatatattt atagaaatat tttaaaatat attgagaaat
     4801 tttttatgct ctactaaaat cttttttata taatattttt atatgtttct aacgaaacca
     4861 aatattagta aaatatgtat ttatttaact aaagttttta aatgggctga ctaagcttaa
     4921 aatataggat attatgagag ttactattga aaaaataaac cctattgcca taaagaaact
     4981 tataaatatg ttatacttaa ctattaaact ggatatattc aagttatcaa atccaaataa
     5041 gtatgtaatt gaacttatta caaaaataac tataactata aagctcagac catttaagct
     5101 attttttaaa tcagcactac taagtgacat atgtgtagat atagaataca ttaaaaacat
     5161 aaatataaaa tacttcaatg aatatacact aggtgttaac aacattattc ttataaaatt
     5221 ggaaatatca cctaaaataa tgtgtataaa accatttata tttaaattat taatcatact
     5281 tacatataac tttaaatcta tattttgagt cactttcata taactatctg gcagtaatat
     5341 cttaaaaatt aaaataatca ttattgttcc acctataata ggtgcaattc ctataaagaa
     5401 atttcctata ctttgataaa gattatcttt tttatagcta tgacttacat atcctagtat
     5461 accatcattt ttactttcta ttggtctgaa aaatttaact gaatttattt tatgcatgaa
     5521 aattaaacac attatcaaat gactcaattc atgaacaaac gttcctatag ctccagttac
     5581 aataattcca gtttttccaa aagatgaaaa tataaattta ttatttagat tttctgtaat
     5641 gctaaaaatc aatccaaata caataaatat tcctatgaaa caaaaaatat ttattacact
     5701 tatttttaaa atttcgatta tataaatcat aagttaagtc ctcatgtaaa agtatttaac
     5761 tactctactt catatccatt acagcttaaa attttacaag cattttctat atctttttct
     5821 tttactaaga tatagtctgt atcataagta gaaattgcaa atatgcttat tttgttgtct
     5881 gctaacaaac tacttaactt agataaaatt cctacaagtg aaaagtctaa aggacctagt
     5941 atcttaagta ttctccactc cttttctgac ttaacatcag aaggaatatt attatttaaa
     6001 catacaacac ttaattcatc atcagttcta gttatagagt aaaacttctc tgtatctatc
     6061 catgttggta ttttactgtc attatttaat ctacatactg catactcttc taccaataat
     6121 tttaatttca taatgtatat ttcctccaat cttatttgtt tacttaagat tatacattaa
     6181 aagttacata aaataaaaca tataaagtaa aaaaggttca ctatagtgtc ctatttctat
     6241 agccaacctt taaaacttaa ttaaattcta ataaagagat atattatcta ggttcaatta
     6301 taagtttaat ggctgttttc ttatcacctt cgatttctat atcagtaaat gcgggaatgc
     6361 aaactaaatc cattccacta ggtgcaacaa aacctcttgc tattgcaatt gattttatcg
     6421 cttgatttag agctccagct cctatagctt gtatttctgc aacgcctcgt tctcttagta
     6481 ctccagccaa ggctccagct acagaattag gattagattt tgatgaaact tttagtacct
     6541 ccatttcaac atctccttgt taatttgtta aagtatccat tacctaaagt actaaatcat
     6601 aattgccatt tactaattac aatcatcatt taaagtatac ttttataaaa atatacttct
     6661 ataatcgttt taagaaaacc tttatttttt ttaaccattt tattatgaaa aaactacaaa
     6721 tttctttata ttctataagc attttccaat atttctaaat tttttatatc tttgagctat
     6781 aatttcctct ttatccatat ctttgtaatg atttaatctt tctaaaatat aagcttttat
     6841 ttcttttgaa acagcttcta catctttttg tgctcctcca agaggttctt ttataatctt
     6901 atctattatt tttaaatcat ataaatcatt acttgtaagc ttcataacat cacaagcttc
     6961 tttagcttta gatgaatctt taaatagaat actagaaagc ccttctggag aaattacaga
     7021 ataaactgaa tgttctaaca tacaaacatc atttcctact ccgataccta aagctcctcc
     7081 actaccacct tcaccaatta caaaagtgat tactggaaca gaaagtttac tcatttcaag
     7141 taagtttctt gcaatagctt ctccttgtcc tctttcttct gcttctagac cacaaaaagc
     7201 tcctgatgta tcaataaacg ttattatagg tctattaaat ttttcagctt gtttcataag
     7261 tcttaatgct tttctgtatc cttctggatg aggcattcca aaatttcttt ttatattttc
     7321 ttttgtatct cttccttttt ggtgtccaac tatagtaaca ttaaactttc ctatctgacc
     7381 aattcctcca accatagaag ggtcatcttt aaaaagccta tctccatgaa gttctaaaaa
     7441 attagaacaa atatgttcta tgtattccaa tgtcgtaggt ctctttatat ctctacttag
     7501 tgttaccttt tcatatgctg atagatgtga aaaagcatct tccttaagct tttccaattt
     7561 ctcattaagt gaatttattt tatcacttaa atctatatta tttgccttag aaatagttat
     7621 taattgttta atatcatttt ctaagacttt tattttttca ctattatttt caatcaaaac
     7681 agttcctcct ttatgcccta tttcttgtgc atagcaagaa tttgatataa tacttccttc
     7741 atttttcttc tatctactat catgtcaata aaaccttttt caagtaaaaa ctcagaagtt
     7801 tgaaatcctt caggaagttt ttgatttatt gtttgctcta ttactcttgg acctgcaaaa
     7861 cctatcaacg tatttggctc agaaattata atatcaccaa gcatagcaaa actagcagtt
     7921 actcctccag tagtagggtc agttagaact gatatatatg gcaatgattt ttcttcaagc
     7981 ttagaaagtg cttgagaagt ctttgccatc tgcataagag ataccatacc ttcttgcatt
     8041 ctagctcctc ctgaagcaga acaaataatt ataggtaaat tattttcagc agcatactct
     8101 attgaataag ttattttttc cccaacaata gaacccatac ttcccatcat aaaatcagga
     8161 ttcattacac aaataactgt tttaattcca tttattcttc cataacctgt gacaacagct
     8221 tctgactctt ttgttttttc cttataagag tctacttttt ctttgtattt aggaaaattt
     8281 agtggatttt gaaattctac atcagaatta aactccataa aagttccttt atcaatcaat
     8341 aaatttattc tttttcttgc tcttaagcca taatgtcttg aacattttgg acatacaaat
     8401 gaattttctt ctatgtcctt tctaaataca tgactatcac aacctttgca ataggtccaa
     8461 aatttatcat ctacactatt ctttttaaag ttgtcatcta aagaaatcgt aacatactta
     8521 gattcttttg atgataaaaa tttttttatc ataatctatt tactccttat aatgtagcaa
     8581 attctttctt cataaagaca tcttctataa atttggtatg atgagtatct tctctaaact
     8641 cctcacttgt tacaagtgcc ttttgaaatt ctacatttgt attaatacct tctacaataa
     8701 tttcgtctag agctctatat attctactta tacattcttc tctagtttca gcccaacata
     8761 ttaacttacc tatcatagaa tcatataaag gtggtatagt atatcctgca tatacaaaag
     8821 tatcaaatct aacaccaaaa cctccaggta aatttaatga ttctatctta cctggtgatg
     8881 gagcaaaatt ctttgatgaa tcttctgcat ttattctaca ttcaatagca tgacctctaa
     8941 aagtaatatc ttcttgttta aaaggaattt tatccccatt agctatagat atttgaagtt
     9001 ttataaggtc aagatttgtt accatctctg taactggatg ttcaacttgt attcttgtat
     9061 tcatctctat aaaataaaag tttttatctt tgtcaactat aaactcaata gtacctgcac
     9121 cgatataacc tactcctttt actatatcta ctgcaatttt atgaagtttt tgtctttctt
     9181 catctgaaag gtatggactt aaagattctt ctattacttt ttgatttcgc ctttgcatag
     9241 aacaatctct atcacctaaa tgtattgcat ttgaatgttt atctccaaat acttgtactt
     9301 ctatatgtct aggattttct ataaactttt ccatatataa atcactatta gaaaatgctg
     9361 ctagagcttc tgaacttgcc atatcaaaat ttgaaaaaag ttcttcttct tttctaacga
     9421 ttctcatacc ttttccaccg cctccacttg aggcttttat cataacagga tatccaattt
     9481 ctcttgcaac ttctaaagct tcttccttag ttttcaaaac agattctgaa ccaggaacaa
     9541 cagggatatt caattccatc atagtttctc ttgctctaga tttatctccc atcaaaatca
     9601 tttgttctct tgttggacct ataaaaataa tattattatc ttcacattgc tttgcaaatt
     9661 caggattctc tgataaaaat ccaaagcctg gatgaatagc atcacacttt aatttaagag
     9721 caagatagat tatattttct atattattat aactcttact tatattattt ggtcctatac
     9781 aaatagattc atcagctata tatctatgaa aacaatcttt atctatttca gaatagatag
     9841 caacagtttt tatacctagt tctttacatg ttctgatgat tctaactgct atatcgcctc
     9901 tatttgcaac tagtattttt tttatcaact taaatacctc ctactacaat ggttttatct
     9961 taaataaagg ttgattatat tctactagtt cttcattact aactaatact tcaattattt
    10021 cacctttaat ttcacttgtt atctcattca taagcttcat tgcttctaat atacataaag
    10081 tgtcgccttc ttcaactaca tcgccaactt taacaaagct atctgcatct ggacttggag
    10141 aatcatagaa tgttcccatc aaaggagcta ctactactga tagattctca ttagatgtga
    10201 caggtgtatc gtttacaact ggcttttcta aagaaagatc cactactgat tcttgttgta
    10261 cacttaaaac aggtgaactt gtagattgag cttttttaga tacttctaat cttaaatcgc
    10321 tactttcaag ttttacatat tctaagttag ttgagtctat ggcctttaat aattccttaa
    10381 tttcattgat gttcattttg ttaccccctt gtattattac ctggtgctaa tattatatca
    10441 caaaaaacaa atttataaaa gaaaaagtgc tgactagaga atcaacacat caatatatct
    10501 tttaatttta aattaacaac cagtaactta tatttgtttt aattttccat tattaatata
    10561 aattataagt ataaaatgaa taaaattcaa tattttttgc aaaatacaag agaatacaaa
    10621 ttaatacctc gggaattttt aagacaaata ccaatattat gcaatttaga cttcgctttc
    10681 tttcaaatta gtatcatttt ctttattttt acataggatg tactttaatt tagctatcaa
    10741 aacattgcta tataggttaa aagttattag aattgcagga attataaagt aaactctagc
    10801 acctataaaa ccaaaaacta ctgtaataag tattaatctt ttatttaaag taaaaaaagg
    10861 tatattaaaa atacttttgt cggatgtttc tggagtataa gaatatataa ctccaaaaat
    10921 caaagtaagc atacaaagtg gaagtagtgt ataacttgaa attattccca aaaatcctat
    10981 actttcaaaa tatttgctag cactatttgt ataaacaaac atgtatccat ttaaatatgc
    11041 gcatatacat gatataatgc caaaagttcc ccctaaggat tgagtgtacc aattaaaaaa
    11101 tttagattcc atatacctca cctcctaaaa ctgtatatat aatgatatgc atttaaatag
    11161 taaaatatat ctttatatgt ttctgaataa aattttgtta atttcattaa tttatgttta
    11221 agaaatttga agtatagtgt agtatatatt aatgtagatg aagttttata gtacttattt
    11281 catagtgctt aatcaagtta tcttattatg gattcaaaag ttgtttgtag ggttttatat
    11341 tttgttgagc tgaaaaattt attataaatg aagggatgtt ttcgctttgg tagatacatt
    11401 agaatttggt cttaaaattt tattttttat attatcaata atttggatgg gtaaaataat
    11461 gattttaaga actgataagc aaatagtaat caatcctttg cttattggta tatctgcaat
    11521 ccttgtgatg ttgcatacct cacagagtaa cattgaattt tttggattag atgtccaata
    11581 tataagaata gttttgtata taatatattc actgataatt ttaataggaa tatgggctac
    11641 taacagaaga aatggaattt tttagataat ctatttctat aaaatttaaa ggttgctagt
    11701 aacaaatcac taatattagc gttctgttac taacaacctt tattttgatt atacacttaa
    11761 attgaaaata gaatgattga ataagttgac agattatttt acattgacag taattagaac
    11821 ttcttgagat gtatttaaat catttttgtc gcttagtata acttttacca ctgctttacc
    11881 tgttttatta cctttaatta tcatatcttc acatgaaagt acactcttat cacttacaga
    11941 tacaataaaa tttaaatctt ttggaaggtt atcagtaact tcccagtatt tataataact
    12001 atcaattttc ttcgtaatta tttttctcaa atcaatactt tcaccttttg ctatatcaac
    12061 attatgatat ttagagtcca gtttatactg attatctttt gtatcaataa aatttaaatc
    12121 gcaatttaca tccacaccat tatgagaaag agaatttact acatcgtcat caatcaaata
    12181 attattggca agatttattg aatccatatc ttttagactt aaagcttcct taggaacctc
    12241 ttttatatta ttattccaaa aaataaaatt gtctacattt tcaagatatg atataccttt
    12301 taaatttgaa atactctcac cagttgcata aaattctcca tctaaagcct ttatattgct
    12361 tatagtcatc tcatctggat ttatatatct ttttacaact gctcttaaat ttgcatcagg
    12421 aaaaatatct ttaagttgat tttcgctcaa aaccttatca tttgaattta ttggacttaa
    12481 agctgctgca gaaataataa atggtattaa attagctaaa ttcatagtac cctcccacat
    12541 aaatttttta ttataataat ttaatttcta tgagagggtt ctgtttcctt gttatatata
    12601 cctactttcg tacactttat taatataaat taaaataaat ttctactatt aaacttataa
    12661 acatattact agttacgttt tttagcttca catctaaata ttcgcatacc ttgtgacata
    12721 aatttgtctt catactctgt tgtaacatta ttttcatact cactatttcc taaatcaaga
    12781 gaaatattct ttaatagcca attatttgca gcaatttcat ttaaactaaa ctcgaataat
    12841 ttttcattat ctgttttaaa gtgaatttcg ccatcatctt ccaaaaccct attgtacatt
    12901 tctaaaaatc cagaatgagt gagtcttctt ttactccatc tatttttagg ccatgggtca
    12961 cagaaattta tataaattct cgataattct ttagcttcaa agtaatccaa aatattgctt
    13021 acatctcccc ataaaaatag tatattattc aaattagaag catctgcttt ttcaacagct
    13081 tttaaaagaa cttcttcctt aagttccatg gcaatataat ttatgtcagg gttctgctta
    13141 gctaaagttg ttataaactt accttttcca gtcccaaatt caacatgtat tggattatca
    13201 tttctaaact ttaaattcca cttgcctttt aatttgtcta tatcgtctct taaaacatat
    13261 tttgtataac ttaaaagctt ttcatctgca cctttttttc gtcttcttct cacaataatt
    13321 ctccttacat ataaaaaatt agtaaaatac atttttatta tacattatct caccaaaaaa
    13381 taaaaagaac tctcttaaaa tagaaattta tttctataaa gagagttcta aacttactaa
    13441 aaacttaatc ttagtggcac cctgaacaac cagagcatcc tcctccacct tgatctttca
    13501 tattttcagg aataactcta aatccaaatc ctgtatcttc tattattata tctccatact
    13561 gactatattc atcagagctc attacaaatt gtaattctcc aacttcataa gttaagtcat
    13621 cttctttttt ctcatctaaa gctaatccaa aagaaggacc tccacaacca acacctgcaa
    13681 agtatactct tatattatta ggtttatctt gattgtcttt taagatactt tttaaagtat
    13741 caatagctgt ttctggtaaa gtaattttca tcaaatcatt ccctttcaaa tattttatta
    13801 aaacaatatc tattatatac ccatacaagg tacataatca attagttttt gcatatttta
    13861 ctaaaacttc tacctaatat tacctaaggc tttaaaatat tttatataat attttattac
    13921 cttaaataaa taccctatca taaacttagt aaacaaataa aattattatt ctaaaaaata
    13981 taataatttt atttgttgtt ttaatattat aacacatttg ataatgtcca attcatatat
    14041 gcaaaattta tatactttaa aatatctaag aaattattca ataaaaaaat actatttttt
    14101 aaaaattatc attattgata aagctctact atttatattt tttagtgtat tcatgtataa
    14161 taagtaaaag cacaatggta tatactgttg tgcttttttg taattaataa acaatatttt
    14221 ggtctataaa atgaaaaatg gctactttcc ataattgatt tcatctgaca taagcaaaaa
    14281 tggtgtccag ctgggtcaat cataactctc cagtcatcag taaattgctc ctctgcgatt
    14341 gtagctccac aatgaattgc atattgaact gcttcttcta aatcattaac agcgaaatcc
    14401 atatgagcca tttgctgttg agattcaggt ttttctggtt ctattatgcc ccaagccttt
    14461 gttttttgca atataaagaa aaaattatat attttaatat tttataatta ttgaaattgt
    14521 ataataaatt caactggata catagtgcgt tttgaaattt cttctaaagc taaaccttgt
    14581 tttaaaagcc tctttatgac gctttccata ctttctgaaa tttctataat atttttatca
    14641 aaatcataaa acctaaaagt tctttgaccc catgggtatt cttttatata atgcaaaaat
    14701 tcaatatttc ctattctatt tatcttactt tcccattgtt tgatgtcatt aacctcaaaa
    14761 tacaactgaa agttatttga ttgttgatat attggtaaat catatccaat tatagcttta
    14821 taattacttt gtaatccaaa tccattttca aatgatacat gttctcctaa atctaatgtg
    14881 attttttgct ccataacatc ttcaaaaaac ttttttgatt tatttatgtc tttgacaatt
    14941 agcaatactc ctccaaattt catcttatca ctatcctttc tttgttataa gtattataac
    15001 ttaaaatttt gcaatttcac tgtaaaaatc agacatatta gctcggtatt tttgaggagt
    15061 tattccacag acaattttaa aatctttaat aaaatgtggt atatcataga atcctaattc
    15121 attacatata gacatcaatg aagttttatt attgtttaga agttttatag atttattaat
    15181 acgtaccaaa cgagaaaatg acttcatact caaccctagg tactgattaa agagtctgtt
    15241 taaatgccta gaactataaa atactttttt agaaatttct tgtgaagata tgtttccaga
    15301 gttttgaata atcaactgaa ttgccaaaat aaactcatat gagtattcaa ttttaatatt
    15361 agaaatcaat aattcttcca actttaaaat caatttatct atagataaag attcattaaa
    15421 tattttttta atttctaaat ctaatgaagt attaattata gaaaatggaa caactttatc
    15481 aataagttca ctttgctgta tacctataag cgggaaaaaa ccagcaggtt gaaattctat
    15541 aattagtata acatcacatc tattagcaat atttcctact gtttttggtt tagtagttgg
    15601 accaaataat agactatgta accctgtggc atcataaaaa aacaccaaag ttacacttcc
    15661 atgaggaata atcgtgtaat tatcagaaat tattgtttga tttggaaacg atatagtaaa
    15721 attcgatatc caatttctta attgtataca aggcaagaga taaacaaaat tgtcttcaca
    15781 aactataagt gacctatttt tatttataaa atgaatactt tcttttttta acatatatta
    15841 tatcctgtcc tatcgtgaat atttattaaa gtaagaagaa tccatattat ctctatatat
    15901 cattaactgc ttttaataat agagatagta tgaatactca ttagatattt aataaacaaa
    15961 taaaattaaa ataatcaata aaaaatatag tacttttatc tgttatttta atattatagc
    16021 acatttatag tatttaactt atatccactt tacatatgtc taatttatat agttaaaaat
    16081 gcttatctca aatacaataa ttagtcctta tacaattaaa ccatctgaaa ctgtaatagt
    16141 acgactacta cttttggctg cttctggtga gtgagttacc ataattatag tttgtccatt
    16201 gtctctgttt attttattca gtaaatctat tatttctatc cctgttttac tatctaaatt
    16261 tccagtaggc tcatcagcaa ataaaatctc tggttttcca attaaagctc gagctatagc
    16321 aacacgttgt tgctgaccac cagataactc tcgtggtgta tgtttacgtc tatcagttaa
    16381 accaactata tctaagattt catctaattg atttttataa tcttttaaat ttttaccatc
    16441 taataacaaa ggaagcatta tattttcctc cacatttaaa tttggtatta agttataaaa
    16501 ttgaaatacg aatcctatat ttctacgacg tattatgctc attttctcat cattaaaatg
    16561 tgatatatca gctccattca tatacacttt tccgctcgtt ggagtatcta aaccacctaa
    16621 aatatataaa agagtacttt taccagaacc agattgaccc atgatagaaa caaattcacc
    16681 tttcattact tgtaaagata cctcttttaa cactcgagtt gttgtatttc caattttata
    16741 ttctttgata atattttttg cttctacagc taaactatta tgtgtaattt tcatattaac
    16801 ctccataatt attcaaactt aatttcttct atcagtttca ttttcttccc ttttataata
    16861 ggcactatcg aacctattaa agttactata attcccaata acccaacaat aataaatgtt
    16921 ttaaaatcta aatctggttt cattgaaatt tttggtcctg caactataaa gatagtttga
    16981 atctcaagta tagatatcac aataccaata acagctccaa gtaaacctga agtaaaccct
    17041 tcaatcaatg tcacttttat attttgttta ttacttagtc ctatagattt atacatagct
    17101 atagaacgtc ttttttgaat ataattaatc agtagattat taataatacc tactgtagca
    17161 agaagaaaaa tgaaataggt catcttattc ataggagaca aaaaactact tatagtattt
    17221 aaagaatcat tattaaattc ttcaactgta cgactccaat tatatgtatc tccaaataaa
    17281 tatcttatct gaatcataac agcatctgga ttgactgctg tatatactaa aaaaccataa
    17341 ttagttttat caaaatcatt aactgcataa tgtgatggta taacagcttc tacatcattt
    17401 gcacgggatt taaaactacc tattatttta taagaaaaat catacttatc attagataga
    17461 gttattgtat ctcctataga taagcctact ttttttagag tatcttcatt caaaataaca
    17521 gaacgtttat cattaaaagt ttctattact tgttttttta tctcaaaatt tgtataattg
    17581 attccaaaca tagagttata tagttttata ttatctgtac cctctagtct tgataatgtt
    17641 acaccattac cagaaatctc attattcata acataaagag gtaatatttt tttaattcca
    17701 tccatatgtc taacatcttc aataaactct tcattcatct ttccatctgc aaaaccttgt
    17761 aattctgcgt cacgaaacac atctgttata taagttttga caaagttacc aacaacactt
    17821 attgcaataa ctgcagaaat acttataaat agtaaagtga tattctgtat tatatttttg
    17881 ttatttttca tatttctagc agctaattta ccctcattcc ctaaaatatt tttataaaca
    17941 aactcaaaaa ctatagacat gatatcagta ataagaggaa tcaacacaat agtagctaca
    18001 attaatccta gtaatgaaaa tccaccagct agatacaatg tattttcagg gtatattctt
    18061 ggaagtaaaa tagataaaat aaacattata cttcctataa aaagtataga acgatttgaa
    18121 acattctttt cttctactgt tcctagtaca atatttttta ttggcaaatg gctagctttt
    18181 ttaacaggta tatatgcact aaatgaagaa acgattattg ctactataac agatataatc
    18241 actccaatgg gtgatattac tactggaatt gatattcctt gttcgagaga atttcctaac
    18301 ccatgaagca ttaaatttaa aacaactaca ccaataggaa tagcaattaa tcctcctata
    18361 cttccgtata atatactttc aagcatcaat atacgagtta cagttttttc attggcacca
    18421 atacttctaa atgttccaat aaaaggaaga cgttctaatg taataacctt ataactgctg
    18481 tatattataa atatactaag ggttaatgca aaaaaactta ttaaaaagaa aggcattgtc
    18541 ttttgtctag catctgaaat tatcttagtt tcatttatag tatttgatac catatatttt
    18601 tcagtagaaa gttcttcgga taatttattt actagatttt ctgtaatttc ttcttctgac
    18661 tctataagaa ctcttgtata tccactgcct ttatttataa tttttgatag agtctctttg
    18721 ggtagcagtg catttacacc tcttgtgttc ctcaaaaata ctgtatcata agatgcaata
    18781 tcactaactt gaaaagtata ggactttcca taaatctgta aagtaataga atcacctttt
    18841 tttattttat attttgatgt aaagcgattt ggaagaataa ttttatcacc agaaaaatca
    18901 gtaatactat cgccattttc taatcgtggc ttgttgattt tatttagttg acttaagtct
    18961 gctgatataa gactaaattc ttcatagtat ccccctttat tataaatagc agagctttcc
    19021 aatacaccaa cctttgattt tatagtattt aaatcaggta tgtcttctaa attggttaat
    19081 atatctggat ttttactttg gacagatata gtcgctgtac catacatacc ttttgccatt
    19141 tttctttgtg cactttcata agataatcca attgagaatg aaacaaaaag taaaactgtt
    19201 gataaaacta tggacaataa cataactgct gttctaattt ttcgttcttt aatatttgtg
    19261 aaaatatact ttaatataat tttcaaattt acaccttctt tccttatcta agatatttca
    19321 atctaatatt tttatacttt aatctaaatt aaatctctaa tagactcctc catactttta
    19381 tcattctatt tataatattt ttaatcaaat caccccttaa ataaaaaaga ttgataaact
    19441 actatataaa tataataatc tatcaacctt aatatatttt ttatttgacc ttaattaacc
    19501 ttaattaaat aggaaaggtg atataaaatg agctacctaa tccaggtata ctttcaacag
    19561 atatattccc tccatgaact tcaataattt gcttcgttat tgctagtcct aaaccagttc
    19621 cttctatttt ttgttttgta ttgcttcctc tataataacg attaaacaaa tttgatgctt
    19681 cttctcttga catccctttt ccattatcag atataatgat ttcaattctt tcatttaatg
    19741 ttatatgtac acaaacttta gtatttttat ctccatatgt aaaagcattg acaataagat
    19801 tactaaaagc tcgttttaat agtgtacaat caaaatcaaa gttaatatta tctatattac
    19861 tcttaaattc aactatattt gattcatatt ctggatagtt taaaatatca atggataatt
    19921 ctttcaaaaa tcttactaaa tcataattat ttttatttaa agggattatt ccatttttta
    19981 attgataggt taattttaaa tcgtttataa gtgtatttgt atattctata ttctttaaca
    20041 tgattgaagc atatttatat actttttcag gtgaataatt agtactacta tctgtaagaa
    20101 gctctgcata cccttttatt ggtgaaagtg gagtttttaa atcatgagtt atatttgaaa
    20161 tccactcttc tctcataata tcagttttat tttgtatctc atcacttcta tgaatttctt
    20221 catttaaaat atttaaacta ttatatatat cagcaaaaac acctttaata ttaactggaa
    20281 gatagcttcg ttttgaaata tcgctaacag cagatgtaat atttgatatg cactttgtta
    20341 cccagtaacc ataagcaatt ccagaaacca aaattattaa aaatataatc cctatgattg
    20401 aaaatacaat tgacttacca cctataaatt tacctccatc aaaaaacata ttcactttag
    20461 atatatttaa tggaaaatat at
//
LOCUS       DAFAZV010000063        18600 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFAZV010000063 DAFAZV010000000
VERSION     DAFAZV010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18600
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.063"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..868)
                     /gene="bclA1"
                     /locus_tag="KOU88_003445"
     CDS             complement(<1..868)
                     /gene="bclA1"
                     /locus_tag="KOU88_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-like exosporium glycoprotein BclA1"
                     /protein_id="HBK3213279.1"
                     /translation="MRNIILYLNDDTFISKKYPDKNFSNLDYCLIGSKCSNSFVKEKL
                     ITFFKVRIPDILKDKSILKAELFIHIDSNKNHIFKEKVDIEIKRISEYYNLRTITWND
                     RVSMENIRGYLPIGISDTSNYICLNITGTIKAWAMNKYPNYGLALSLNYPYQILEFTS
                     SRGCNKPYILVTFEDRIIDNCYPKCECPPIRITGPMGPRGATGSTGPTGVTGPTGSTG
                     ATGEIGPTGVTGPTGNTGATGSIGPTGVTGPTGNTGVTGSIGPTGVTGPTGNTGVTGS
                     IGPTGATGPTGNT"
     gene            complement(1546..2070)
                     /locus_tag="KOU88_003446"
     CDS             complement(1546..2070)
                     /locus_tag="KOU88_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK3213280.1"
                     /translation="MENKNPIVTIEMENGKEIKIELYPNIAPNTVKNFVSLVNEGYYN
                     GIIFHRVIPGFMIQGGCPNGTGMGGPGHSIKGEFSGNGFTNNLKHERGVISMARTMAP
                     NSAGSQFFIMHKNSPHLDGQYAGFGRVIEGMDTVDEIASVRTDSADKPQTPQIMKSVT
                     VETFGIDYSDVEKN"
     gene            complement(2135..2887)
                     /locus_tag="KOU88_003447"
     CDS             complement(2135..2887)
                     /locus_tag="KOU88_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBK3213281.1"
                     /translation="MKLGLCLEGGGAKGAYQAGVVKALYDGGINKFYSISGTSIGAIN
                     GYYLYTGNVDNLEKMWTNIKDIQNGNVKIVNNTVDNSPAIDNLRELDDSNIEEMNFYV
                     NYVEVDNKVVSEKIVDVSKMPRNEAIISISYSGLLPSNPNATLGFKEQFVKDVQEGIY
                     DGFKLDGGLIRSALIEPLIGDNVDKIILISTKYNYELPEDIKKVYDEDKIIVVRPNTQ
                     FAPKDTLNFDDEFCKTIYQEGYEIGKNILDRL"
     gene            complement(2918..4216)
                     /locus_tag="KOU88_003448"
     CDS             complement(2918..4216)
                     /locus_tag="KOU88_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M18 family aminopeptidase"
                     /protein_id="HBK3213282.1"
                     /translation="MDSINFAKNLIDFIYDSPSSFHAVESTKEILDKNGFEELVLNQR
                     WNLRVGGKYYITKNLSAIVAFVVNSEGIERDGFRIIGSHSDSPTFSIKPNAEIEAEKS
                     YLKLNTECYGGAILSTWLDRPLGIAGRVVLKGDSILKPNERLIDFKKPICIIPNLAIH
                     LNRSINDGHSYNKQKDMLPLVGMLNDTLEKDNFLIKQIASNLDVNMEDIIDFDLFLYE
                     FEKGSLIGANDEFISIGRQDNLAMVHASLNALVNTKGQHGVNVMAVFDNEEVGSSTKQ
                     GADSNMLLNILERICISMGKDREGFFESIYSSFMISSDLAHAIHPNIPEKHDPTNKPI
                     MGKGPVIKINASQAYTSDGYSIAIYKNICREANVEYQEFVNRSDERGGSTIGPISSTH
                     IDIPSVDVGSPILAMHSIRELGNVEDHYSIYKTFSKFFEI"
     gene            complement(4233..6497)
                     /locus_tag="KOU88_003449"
     CDS             complement(4233..6497)
                     /locus_tag="KOU88_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3553 domain-containing protein"
                     /protein_id="HBK3213283.1"
                     /translation="MNLDTLNPAQREAVEKTEGPVLILAGAGSGKTKVLTTRIAYLIE
                     DKGVQAPNILAITFTNKAANEMRERVEQNIGPETKDMWISTFHSCCVRILRKDINKIG
                     YNRSFVIYDSADQVTLVKDCLKELNLSDKVFEPKAVISAISGAKDKLYTPKQFKDINM
                     ADNRMVKIADIYALYQDRLKRNSALDFDDLILKTVELFKANDEVLAYYRSRFRYIMVD
                     EYQDTSKAQYELIKLLAREHQNICVVGDDDQSIYGWRGADIRNILEFEKDYDNVHVVK
                     LEQNYRSTQVILDAANKVISNNIERKRKKLWSEKKEGELIKIQLTGSEIEEADFIADS
                     IAQIARKENRPYKDFAVLYRANAQARPVEDALNRSQIPYNIYGGTKFYERKEIKDLLA
                     YLRVIQNPQDDISIKRIINVPRRGIGLRTIEKIEDRANLKQESIYSVLIDIETNSDIS
                     TKARASISGFVDIIGTLRTIKEVYPVSKLIEKVLDTTGYMDELVEIRNKNEKDLTGKG
                     EEAQDRIDNLREFISIALEFESSNDDTYENKDLETFLTSIALTSESNDEEDNDRVSLM
                     TIHTSKGLEFPVVFLTGMEEGLFPISRAIKSMSDSQIEEERRLCYVGITRAKEELYMS
                     LTEKRTLYGKTNVAIASRFMEELPEECIERLYKVKKELSYSKASYNMLDKYTKKYMST
                     ISKSKVADKVNATIKDSNKETNPDDIKLGSKVHHPKFGVGTVVSIIGTDVTIAFDQQG
                     IKKINKEYTTLNIL"
     gene            complement(6752..7570)
                     /locus_tag="KOU88_003450"
     CDS             complement(6752..7570)
                     /locus_tag="KOU88_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009904855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK3213284.1"
                     /translation="MFKINNLTYQYEKNTNALLNINMDFSKGNVIGIIGSNGSGKSTL
                     FMNLMGILKPTSGEILFKEEKLKYDKRSLYNLRKNVGIVFQDPEKQIFYSKVYDDIAF
                     AMRNIGMDEKTIKERINKALVAVNGIDFIDRPVHFLSYGQKKRVAIASVIAMENEIVL
                     LDEPTAGLDPVSTRSIVDIIKGLNKNNIKIVISSHDMNLMYEICDYIYVLDKGILIDE
                     GKAENVFINENNIIQAGLESPWLVKVHRNMNLPLFKKEEDLYKYWKERELNTNK"
     gene            complement(7563..8261)
                     /gene="cbiQ"
                     /locus_tag="KOU88_003451"
     CDS             complement(7563..8261)
                     /gene="cbiQ"
                     /locus_tag="KOU88_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ECF transporter T component CbiQ"
                     /protein_id="HBK3213285.1"
                     /translation="MLIIDKYAYTNRLSKVNPNKKVAIGVIFLIASMVIQNIFILSGI
                     MILMSILVVCVAGIDLKNYLKLLRIPMYFLFLSIGITLVNISFNKADLLYSFEFFSFN
                     VGISKASIDMSIHVLFRAMSCLTCVYFCILTTPFNQLIFFFKKLHLPDTFVELSMLIY
                     RFIFIFLEEFSEIYKSQELRFGYINLKTSYKSLGILGSMLYKRLMTRYDDMCISLDIK
                     LYDGKFHIVGDNDV"
     gene            complement(8264..8542)
                     /locus_tag="KOU88_003452"
     CDS             complement(8264..8542)
                     /locus_tag="KOU88_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK3213286.1"
                     /translation="MSAKTKTNILLLLLVVALIIFPLLVNSGAEYGGADGQAESEITK
                     INPNYKPWFSSPYEPPSGEIESLLFSAQAALGAGVIGYILGLQKGKRS"
     gene            complement(8532..9284)
                     /locus_tag="KOU88_003453"
     CDS             complement(8532..9284)
                     /locus_tag="KOU88_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006440549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter permease"
                     /protein_id="HBK3213287.1"
                     /translation="MKQNIKLGVIAALMLIILTPVTSNAMHIMEGYLPVKWSIAWGVI
                     FIPFFLFGLKSIGKIVKQDPKKKVLLALCGAFVFVLSALKIPSVTGSCSHPTGVGLGA
                     IMFGPSVMFVLGTIVLIFQALLLAHGGITTLGANAFSMAIIGPIVSFLIFKALKKKDG
                     NNAIPVFLAAAIGDLATYTITSIQLALAFPDPSGGVMASAIKFLGIFFMTQIPIAIAE
                     GILTVIVYNLITENGEKSILENNDKGVKANEC"
     regulatory      complement(9466..9658)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            complement(9790..11562)
                     /locus_tag="KOU88_003454"
     CDS             complement(9790..11562)
                     /locus_tag="KOU88_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase activation-like protein"
                     /protein_id="HBK3213288.1"
                     /translation="MKWIYDDYEFENRANNLSWTIAGDYNESIDISEKDYSSKEIGLY
                     FAIIAGARRKYVDWDIVKKYLTNRIRKGYNKDIILGLIQVILNTIVEEKVIKDRPGIE
                     DIRRNAYKDIVSRFTKIHNDNIMDKIKYTFVLYSMDKHPALDSMTRRIVNDIRNIDTN
                     QDIMEILKALDVIYLTYFEYILNGEENSLIDENNVESVEVNFDTFADFMYEELYSDEE
                     ENIIESDIDSISSSMLVEGVGDFDDSKCSNSADRVIYVDEDTANKIYSKIEHYYGKTY
                     LSKGEIKKIETQNCRNVHEGCRIHFTDGVLRSECNNVFQLKYVTRQKENNLGKFREHA
                     RMYRQQIKRLKESLSRILIEENAKSRVYSDCGTILANRAWRVGRSNNNKIFYKDIENE
                     KGKYVIDILLDASGSQSRNQGNVAIQAYIIANALTEVGIPNRVMGFSSFLDYTILKRF
                     KDYDDSIKNSENIFEYFCAGNNRDGLAIKSICSGLINRDEENKILIVLSDGRPNDVKI
                     GKSSERTLRGEKAYRGIVGLRDTANEVRKARKQNILVLGVFTGKESELEAERLIYGND
                     FIYSRDITRFSDVVSMYLKKIIRN"
     gene            complement(11576..12505)
                     /locus_tag="KOU88_003455"
     CDS             complement(11576..12505)
                     /locus_tag="KOU88_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3213289.1"
                     /translation="MDIIDNLRVQGVDEKLIEDVLYFRNYYGLEKDLEYRVTKSKTYF
                     YGKDILSMCIAAILEEENILLSGPKATGKNLLADNLGEIFNRPQWNTSFHINTDSSTL
                     IGTDTFIDNEVKLRRGSVYECAINGGFGVFDEINMAKNDAIVVVHSALDYRRIIDVPG
                     YERVNLHPATRFIGTMNYEYAGTKELNEALVSRFMVIDIPPIEEDKLMMILKNEFSDA
                     DEEKLIHFAGIFLDLQLKSQNGEISSKAIDLRGLMASLKTIRRGLKPTLAINMGLTGK
                     TFDVYEKEMVGDVIKTRIPNKWESIDVFPISHI"
     gene            12734..12922
                     /locus_tag="KOU88_003456"
     CDS             12734..12922
                     /locus_tag="KOU88_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213290.1"
                     /translation="MEYMSCPEVAKKWGISERRVQKLCEESRIPGVSKLGYMWLIPKN
                     AEKPVDGRTKRRKEVQYE"
     gene            12915..13616
                     /locus_tag="KOU88_003457"
     CDS             12915..13616
                     /locus_tag="KOU88_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213291.1"
                     /translation="MNSVLIIDDDKELCALMKKCVEQENLSAITAHGGAEGLHLVDKN
                     RHTLSLVILDIMMPDIDGFQVLKKIRETSNIPVIMLTAKNDEDDKVSGLRLGADDYLT
                     KPFSINELMARVNSLIRRYTMLNPAFITDTDFIIINGMIIDKTNRIVSVNNIPVQLTS
                     KEFDLLAFLASNKGRVFTKKQIYTQVWEEEYAFDDSNIMSFISKLRKKIEPDPNHPFY
                     ILTVRGVGYRFNKEA"
     gene            13618..14541
                     /locus_tag="KOU88_003458"
     CDS             13618..14541
                     /locus_tag="KOU88_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3213292.1"
                     /translation="MNTSVYLLLILALSLIIIAYLVSVLLRVRIQLTLIKDALEDIKN
                     GNLNRRILTDENDITKQICYDINEIAINSQFQLIQQKQSEQAYKQLMTSLSHDVKTPL
                     ASLVGYLEAVESKIVVGEEKDEYIHVASNKAHYLKNFVENLFEWVKLDSKEQVFHFDI
                     FDLNELSRNIISDWIPVLESSHFEYEFDIPEIEYFLRIDANAYTRIINNLLQNIITHS
                     SGNKMTLRIFENKEQAQIIITDNGKGISSDNLPHIFERLYQCDHSRASKGNGLGLAIA
                     KELINAHKGNITANSTPGMGTEFTILLPKAL"
     gene            14698..15621
                     /locus_tag="KOU88_003459"
     CDS             14698..15621
                     /locus_tag="KOU88_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213293.1"
                     /translation="MNDFVIETKQLTKIYGNQTVVDKVNLHVKKGRIYGLLGRNGAGK
                     TTIMKMILGLTSITYGEVDVFGENIKGREKQVYPRIGAIIETPGFYPNLTGTENLEIF
                     AKLRGTAAPNSVKRALEIVGLPYKNKKLFSKYSLGMKQRLGIANAILHDPELLVLDEP
                     TNGLDPIGIAEMRKFIRDLSVEHGKTILISSHILSEISLLADDIGIIDHGVLLEESSM
                     SELEKKNSKYILLQVSDIPKTSLILERQFNTKDYSVQDDYTLHLYNTNLDMGEINKAL
                     VMQNVTVISSQLCNDTLEDYFKKITGGEGIA"
     gene            15614..16351
                     /locus_tag="KOU88_003460"
     CDS             15614..16351
                     /locus_tag="KOU88_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213294.1"
                     /translation="MLKLIQTEFLKLRRRKLIWLMLLSALIMPFFALLYFNYFGKTGV
                     EPIKFYKWSAFGYTLWIILPVVLGIFCTMLIHEENQYDMLKQLWIVPISKMGYFFSKF
                     FVVLIYSICFMLITAVASVLFSVLSGYVVFSWASILYLLKKCLEIGVITAFVMLPILA
                     IATSQKGYILPICITLVYAFSGFVIMTINMYLHPLSSMGVIIMRNKDIPGLIFSQEIN
                     VPLAFLCICIWSIVSVLFANIALGRRK"
     gene            16362..17135
                     /locus_tag="KOU88_003461"
     CDS             16362..17135
                     /locus_tag="KOU88_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213295.1"
                     /translation="MWKLLWAECQKIRRSKIVWITVFASIMIAVIVFAGGQDVYNDPD
                     LHYGLKSVYDGSRYIDNAGWYMDAVQPWSTFFVLPAVIALLGSYIICREEEEDTIKSL
                     RLIPINETNLTIAKMIITFIFSILLYLLLFTITFLTESVLHFSDLSTKLVLSCMKEYF
                     LDGIGVFFAISPIIALVSRMKKGYWLALVFTEVYSIAGLFAGMSNVLQTFFPIAAIFN
                     ISGYYITTGEKIMGSIISLLLCACLSAFILKGLKHNEKN"
     gene            complement(17676..18284)
                     /locus_tag="KOU88_003462"
     CDS             complement(17676..18284)
                     /locus_tag="KOU88_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBK3213296.1"
                     /translation="MSVINSFILQYGLISVFVLIMIEYACFPLPSEVVLPLCGAIAAR
                     NHFGFLTILILSIIAGILGSIFCYTVGNWGGKSIINKIIEICPKAKKGIFASQDYFNK
                     YSSISVCVCRLIPLCRTYISFIAGIAGQNIITFVISSIVGITIWNTSLISIGYIFSES
                     WVRIMSHYNDYKFLVLIIPISIIFIGFVIKSFIHKKHHKIRL"
     gene            complement(18462..18578)
                     /gene="rrf"
                     /locus_tag="KOU88_003463"
     rRNA            complement(18462..18578)
                     /gene="rrf"
                     /locus_tag="KOU88_003463"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         5975 a         3223 c         2324 g         7078 t
ORIGIN      
        1 ctgtatttcc tgttggacct gttgctcctg ttggtcctat acttcctgtc actcccgtat
       61 ttcctgtcgg acctgttact cctgttggtc ctatacttcc tgtcactccc gtatttcctg
      121 tcggacctgt tactcctgtt ggtcctatac ttcctgtcgc tcctgtattt cctgttggtc
      181 ctgttactcc tgttggccct atttctcctg tcgctcctgt acttccggtt gggcctgtta
      241 ctcccgttgg tcctgtactt cctgtcgctc ctcttggtcc cattggacct gtaattctaa
      301 ttggaggaca ctcacattta ggataacaat tatctataat tctatcttca aatgttacaa
      361 gtatatacgg tttgttacaa cctctactag atgtaaattc aagaatctga taagggtaat
      421 ttaaagataa agctaaccca taattaggat atttattcat tgcccatgct tttatagttc
      481 ccgtaatatt taaacaaata tagttggatg tatcacttat cccaattggt aaatatcccc
      541 taatattttc catagacact ctatcattcc atgttatagt tcgtaaatta taatattcac
      601 ttattctttt aatttcaata tctacttttt ctttaaaaat atgattctta tttgaatcaa
      661 tatgaataaa taactctgct tttaatatac ttttgtcttt taatatatct ggtattctca
      721 ctttaaaaaa agtaatcaac ttttctttta caaaactatt tgaacattta cttcctatta
      781 agcaataatc taaattacta aagtttttat ctggatattt tttagatata aaagtatcat
      841 catttaaata aagtataata tttctcattt ataatccctc cattttgggt ctatatcata
      901 ctatgtttaa aatgcatgct tagttacaat acaattaaaa tttatagtat taaattttta
      961 tataataatg ctgatttcta caaaaaaaga acatgtcatt agaaatttct aatagcatgt
     1021 tctttttcat tattatatat tacactttaa attattcctt gactggctta gctggtgtaa
     1081 actaaaccag tctttctaaa atattaagca cttttttctt attatgtttt ttaggattta
     1141 ttgtctatat tattgtaaac caaagttata aaattgtaaa tagaatatat taccataaca
     1201 atattttttt ataagtaaaa attataaaaa actttatttt tgttaaatag aataaataaa
     1261 ataagtttaa aaaatactga aataagtgtt ttccacatat tttatatatt tatttaatac
     1321 attattattt aaaaataaat atataaacaa tcataataaa atttttttaa taaaacttta
     1381 ttttttagtt aaaatcatac aatatataga tttccacaat acaaataaat taaaaagtga
     1441 aatgtatttg tctaaaaaca taataacatt tcactttatc ctcattttta agtaatatat
     1501 atttttaatt tttatttata actaaatcta gtttttatat aaattttagt ttttttctac
     1561 atctgagtaa tctattccaa aagtttctac agtaacagat ttcataattt gtggagtttg
     1621 tggcttgtca gctgaatctg ttctaactga tgctatttca tcaactgtat ccataccttc
     1681 tatcactcta ccaaaacctg catactgacc atctaagtgt ggtgagtttt tatgcattat
     1741 gaaaaattga gaaccagctg aattaggtgc catagttcta gccattgata tgactcctct
     1801 ttcatgtttt aaattgttag taaatccatt accactaaat tcacctttta ttgagtgacc
     1861 tggaccaccc attcctgtac catttgggca tcctccttgt atcataaatc ctggtattac
     1921 tctatgaaat attattccat tgtaatatcc ttcatttact aatgatacaa agtttttaac
     1981 tgtatttgga gctatatttg gatataactc aattttgatt tcttttccat tttccatttc
     2041 tatagttact ataggatttt tattttccat aatttattac cttccttttc attagttaaa
     2101 ttacataatt acatttatta tattatactc taaattaaag tctatcaagt atattttttc
     2161 ctatttcata tccttcttga taaatagttt tacaaaactc atcatcaaag ttaagcgtgt
     2221 ctttaggagc aaattgagta ttaggtctaa ctactattat tttatcttca tcatatactt
     2281 ttttaatatc ttctggcaac tcataattat attttgtgga tattaaaata attttatcca
     2341 cattatcccc aattaatggt tcaattaatg cacttctaat taaacctcca tctaatttaa
     2401 aaccatcata aattccttct tgcacatctt tcacaaattg ttctttaaat ccaagagttg
     2461 cgtttggatt tgatggtaac aacccactgt atgaaatgct gataatggct tcattacgag
     2521 gcatttttga tacgtcaaca atcttttctg atactacttt attatcaact tcaacataat
     2581 taacataaaa gttcatttct tctatattac tatcatctag ttcccttagg ttgtctatag
     2641 caggagaatt atccacagta ttatttacta tttttacatt tccattctgg atatctttta
     2701 tatttgtcca cattttctcc aagttatcaa cattccctgt gtacaaataa tatccattta
     2761 ttgctcctat tgatgtccct gaaatcgaat aaaatttatt tattcctcca tcatacaagg
     2821 ctttaactac tcctgcttga taagcccctt ttgctcctcc accttctaaa cataatccta
     2881 atttcatagt ctcatctcca aattgtttat cttatattta tatttcaaaa aacttactaa
     2941 atgttttata tatactatag tggtcctcaa catttcctaa ttctcttata gaatgcattg
     3001 ctaaaattgg acttcccaca tccacagatg gtatatctat atgagtagaa gatattggac
     3061 ctatagtact tcctcctctt tcatctgacc tattaacaaa ttcttgatac tcaacattag
     3121 cttctctaca tatattttta taaatagcta tagaatatcc atcactagta tatgcctgac
     3181 tagcatttat ctttataacc ggaccttttc ccattattgg tttattagtt gggtcatgct
     3241 tttctggaat gtttggatga atagcatgag ctaaatctga tgatatcata aaagatgaat
     3301 aaatagactc aaagaatccc tctctatcct tacccattga tatgcaaatt ctctccaata
     3361 tatttaacaa catgtttgaa tctgcacctt gtttagtaga gctaccaact tcttcattgt
     3421 caaatacagc cattacattt acaccatgtt gacctttagt attaacaaga gcattcaaac
     3481 tagcatgtac cattgcaaga ttatcttgtc tcccaataga tataaattca tcattagccc
     3541 ctattaaact tcctttttca aattcatata aaaataaatc aaaatctata atatcttcca
     3601 tatttacatc taagttagat gctatttgct ttataagaaa attatctttt tctaatgtat
     3661 catttaacat cccaactaaa ggtaacatat ctttttgctt attatatgag tgaccatcat
     3721 ttatacttct atttaaatgt attgctagat ttggtattat acaaattggc tttttaaagt
     3781 ctataagcct ttcatttggt tttaatatac tatcaccttt taaaactact ctaccagcta
     3841 tcccaagagg tctatctaac catgtactta atattgctcc tccatagcat tctgtattta
     3901 acttcaaata agatttttca gcttctattt ctgcattcgg tttaatacta aatgtaggag
     3961 aatctgaatg agagcctatt attctaaatc catctctttc tataccttct gaatttacta
     4021 caaaagctac tatagctgat aaattcttag taatataata ctttccacca actcttagat
     4081 tccatctttg attcaaaact aattcttcaa atccattttt atctaagatt tccttagtac
     4141 tctcgactgc atgaaaagac gacggactat catatatgaa gtctattaag tttttagcaa
     4201 agtttatact atccattcct catttacctc cattataaaa tatttagtgt tgtatattct
     4261 ttatttattt ttttaattcc ctgttggtca aaagctatag taacatctgt accaattata
     4321 gaaaccactg tcccaacccc aaatttagga tgatgtacct tagaaccaag ttttatatca
     4381 tctggattag tttctttatt agaatctttt attgtagcat taactttatc tgcaacttta
     4441 gatttgctta tagtactcat atacttttta gtatatttat ctaacatatt ataacttgct
     4501 ttagaatagc ttagttcttt ttttactttg tacaatcttt ctatacattc ttctggcagt
     4561 tcttccataa atcttgaagc tattgcaaca tttgttttac catataatgt tctcttctct
     4621 gtcaatgaca tatatagctc ttctttagct ctagttatac caacataaca aagtcttctc
     4681 tcttcttcta tttgtgaatc actcatagat tttatagctc ttgatatagg aaataaccct
     4741 tcttccatac ctgttaaaaa cacaacaggg aactctaaac ctttagatgt atgaattgtc
     4801 ataagcgaaa ccctatcatt gtcttcttca tcatttgatt cagatgtaag tgctatactt
     4861 gttaggaatg tctctaagtc tttattttca taagtatcat cattactact ttcaaactcc
     4921 aaagctatag aaataaattc tctcaaatta tcaattctgt cttgagcttc ttcacctttg
     4981 cctgttaaat ctttttcatt tttatttctt atctctacaa gctcgtccat atatcctgta
     5041 gtatccaaga ctttttctat aagtttgcta acaggataaa cttcttttat agttctaaga
     5101 gtccctataa tatcaacaaa tccacttata cttgcccttg ccttagtaga tatatctgaa
     5161 tttgtttcta tatcaattaa tactgagtat atactttcct gttttaagtt agctctatct
     5221 tcaatttttt ctatagttct aagccctata cctcttctag gaacatttat aatccttttt
     5281 atagatatat catcttgtgg attttgaata actcttaaat acgccaacaa atcctttatt
     5341 tcttttctct catagaattt tgtaccacca tatatattgt atggaatttg acttctattt
     5401 aaagcgtcct ctacaggtct tgcctgtgca tttgctctat aaagtactgc aaaatcctta
     5461 taaggtctat tttcttttct agctatttgt gcaattgaat cagcaatgaa atcagcctct
     5521 tctatttcgc taccagttaa ttgtatcttt ataagttctc cttctttttt ttcactccaa
     5581 agcttttttc tttttctttc tatattatta gatatgactt tattagctgc atctaatatc
     5641 acttgtgtag acctataatt ttgttctaac tttacaacat gtacattgtc ataatctttc
     5701 tcaaattcaa gtatgtttct tatatctgca cctctccatc cataaatact ttggtcatca
     5761 tctccaacaa cacaaatatt ttgatgttct cttgctaata attttatcaa ttcatattga
     5821 gctttacttg tatcttggta ctcatctacc attatgtatc taaatctact tctgtaatat
     5881 gctaacactt catcattagc cttgaaaagt tctacagttt taagtattaa atcatcaaag
     5941 tcaagtgcac tatttctttt taaacggtct tgatatagcg cataaatatc tgcaatctta
     6001 accattctat tatctgccat attgatatct ttaaactgct ttggagtata aagtttgtct
     6061 tttgctcctg aaattgcact tataactgct tttggttcaa acactttatc acttaaattt
     6121 aattctttta gacagtcttt aaccaatgta acttggtctg ctgaatcata aattacaaaa
     6181 cttctattgt aaccaatctt atttatatct tttcttagta tacgaacaca gcaagaatgg
     6241 aatgtactta tccacatatc cttagtttca ggacctatat tttgttcaac tctctctctc
     6301 atttcatttg cagctttgtt tgtaaatgtt atagctaata tatttggtgc ttgtacacct
     6361 ttatcttcta taagatatgc tattcttgtt gttaatacct tagttttacc tgaaccagca
     6421 ccagccagta taagtactgg accttcagtc ttttctactg cttctctttg agcaggattt
     6481 aatgtatcta aattcatatt tctcctcctg ttaacagcca taaatatatt ttaatctaaa
     6541 atatgaatta cttcaaatta taattatgta ttatattaat agattatttc caatatatta
     6601 caattaaata acatttttcc atataattta tttcattgtt taataaaaaa aataacctta
     6661 tgatttgggg aatcataagg cacctttaag gggtctaggt taagggttat tatatataaa
     6721 tctatttttt taaaataggt ttagggctta attatttatt tgtattaagt tctctttcct
     6781 tccaatactt atacaaatct tcttctttct taaataaggg taaattcata tttctatgta
     6841 cttttactaa ccatggggat tctaggccag cttgtataat attattttca tttataaaca
     6901 cattttctgc ttttccttca tcaatcaaaa tccccttatc caatacatat atgtaatcac
     6961 atatttcata cattaaattc atatcatgac tggatattac tatttttata ttatttttat
     7021 ttaatccctt tattatatct acaatagacc tagtacttac tgggtctaaa ccagctgtag
     7081 gttcatcaag taatacaatt tcattttcca ttgctataac tgatgctatt gccactcttt
     7141 ttttctgtcc atagctaaga aaatgtactg gcctgtctat aaaatctatt ccattaacag
     7201 ctactagagc tttgtttatt ctctctttaa ttgttttttc atccatacca atgtttctca
     7261 ttgcaaaggc tatatcatca tatacttttg aataaaaaat ttgtttttct gggtcttgga
     7321 agacaatacc tacatttttt ctaaggttgt ataaacttct cttatcatat tttaactttt
     7381 cttctttaaa aagaatttct ccagatgtag gctttaatat acccattaaa ttcataaata
     7441 atgttgattt tcctgaacca tttgaaccta ttatacctat aacatttccc tttgaaaaat
     7501 ccatattaat gtttaatagt gcattggtat ttttttcata ttgatacgtt aaattattta
     7561 ttttaaacat cattatcccc tactatgtga aatttaccat catacaattt tatgtctaat
     7621 gatatacaca tatcatcata ccttgtcata agtcttttgt acagcatact tccaagaata
     7681 cctaaggatt tatatgaagt ttttaaattt atatatccaa atcttagctc ttgtgacttg
     7741 tatatttctg aaaattcttc taaaaatatg aatataaacc tatatattaa cattgataac
     7801 tcgacaaaag tgtcaggtaa atgaagtttt ttaaaaaaga atattaattg attaaaaggt
     7861 gttgtaagta tacaaaaata cacacaagtc aaacaagaca tcgctctaaa taacacatga
     7921 atagacatgt caatagacgc ctttgatatt cctacattaa aactaaaaaa ttcaaaacta
     7981 tataataaat ctgctttatt aaaagatata tttacaagag ttattcctat actaagaaat
     8041 aaaaagtaca ttggtattct aagtaatttt aaataatttt ttaaatctat tccagccaca
     8101 caaacaacca aaatactcat taaaatcata attccactta aaataaatat attttgtatt
     8161 accatagaag caatcagaaa aattactcct atggctactt ttttgtttgg atttacttta
     8221 ctcaatctat ttgtatatgc atatttatca attataagca tgattaactt ctctttcctt
     8281 tttgaagacc taatatgtat cctattacac cagcccctaa agctgcttgt gcagagaata
     8341 ataaactttc tatttctcca cttggtggct catatggact gctaaaccat ggtttgtaat
     8401 ttggatttat cttagtaatt tcactttcag cttgaccatc tgctcctcca tattcagcac
     8461 ctgagttgac aagtaatggg aatataataa gagctactac taataaaagt aataatatgt
     8521 tagtttttgt tttagcactc attagcttta actcctttat cattattttc tagtatgctt
     8581 ttttctccgt tttctgtaat taaattatat acaattacag taagtatacc ttctgctatt
     8641 gctattggta tttgagtcat aaagaaaatt cctaaaaatt taattgctga agccattacc
     8701 ccacctgatg ggtctgggaa agccagtgct aattgtattg aagttattgt atatgtggct
     8761 aagtctccta ttgctgctgc aagaaatact ggaatagcat tatttccatc ttttttcttt
     8821 aaagccttaa atattaggaa tgatacgatt ggccctatta tcgccattga aaaagcatta
     8881 gctcctaaag tagttattcc tccatgtgct aataacaatg cttggaatat taaaactata
     8941 gttccaagaa caaacattac gcttggtcca aacattattg ctccaagacc tacaccagta
     9001 ggatgtgaac aacttcctgt tactgaaggt atttttagtg ctgataatac aaacacaaat
     9061 gctccacata aagctaataa tactttcttt ttagggtctt gctttactat tttacctatt
     9121 gattttaatc cgaataagaa aaatggtata aatataactc cccatgctat agaccatttt
     9181 actggtaagt aaccttccat tatatgcatt gcatttgatg taactggagt taaaatgatt
     9241 aacataagtg cagctataac ccctaattta atattctgtt tcatcttagt atccctctct
     9301 ccctttctaa taattaaaac ataataatac atgtctgatt tatttaataa aataaaaaag
     9361 cctaactcga tggttaggct tctaattttc cacaatctaa atacaaacac ataaaacaaa
     9421 catatctgta taattattat aagaaacttt ctccatcccc gaagaaatta ctttaatatt
     9481 ttaggcaggt ctcctgactt agcttcatcc tactcctctt ccttcccatg agatataaaa
     9541 aatatcatca tagtggctaa caaaagtttc gtctgcatca cagtagcggg ggctgtaaag
     9601 gaatttaacc tttttcccta ttaatcttgc ttaaagaacc tataatatta tatatttaat
     9661 ttttaaattc ttcttaaatt attttctata taaatcattg tatacctttt ctgtgaaaat
     9721 ttctacattt tttataaatt ttattcattt ttatattttt atgtatataa attctttttt
     9781 gtaagtttat taatttctaa ttatcttctt taaatacatt gaaactacat cagaaaatct
     9841 agttatatct cttgaatata taaaatcatt tccatatatt aatctttcag cttcaagttc
     9901 tgattctttt cctgtaaata ctcctaatac taatatattt tgctttctag cttttctcac
     9961 ttcattggct gtatctctca aaccaactat acccctataa gccttttctc ctcttaatgt
    10021 tctctcacta ctttttccta tctttacatc atttggtctt ccatcgctga gaactatcag
    10081 gattttattt tcttcatctc tatttattag accactacat atagatttta ttgccaaacc
    10141 atctctatta ttaccagcac aaaaatattc aaatatattt tcactatttt ttatactatc
    10201 atcataatct ttaaatcttt ttaatattgt atagtctaaa aaactagaaa atcccatcac
    10261 tctatttggt atgccaactt ctgttagagc atttgcaatt atgtaagctt gaattgccac
    10321 atttccctga tttctacttt gagagccact tgcatccaat aatatatcaa taacgtattt
    10381 ccctttttca ttttctatat ctttataaaa tattttatta ttattacttc taccaactct
    10441 ccaagctcta tttgctaata tagtaccaca atcagaatat actctacttt tagcattttc
    10501 ttctattaaa attcttgata gactttcttt taatctcttt atttgctgcc tatacattct
    10561 agcatgttct ctaaattttc ctaaattatt ttctttttgt cttgttacat attttagttg
    10621 aaatacatta ttacactcac ttctaagaac tccatctgta aagtgtattc tacaaccttc
    10681 atgaacattt ctacaatttt gtgtctcaat ttttttaatt tcacctttac tcaaataagt
    10741 ttttccataa taatgttcta tttttgaata tatcttattt gcagtgtctt catcaacata
    10801 tataactcgg tctgctgaat tgctacattt agaatcatca aaatccccta caccttctac
    10861 aagcatggat gaagatattg aatctatatc actttcaata atattttctt cttcatcact
    10921 ataaagttct tcatacatga aatcagcaaa tgtatcaaaa tttacttcta cactttctac
    10981 attattttca tcaataagac tattttcttc tccatttaat atgtattcaa aataagttaa
    11041 atatataaca tctaatgctt ttaaaatctc cataatatct tgattggtat ctatatttct
    11101 tatatcatta actattcttc tagtcatact atctaatgct gggtgcttgt ccatactata
    11161 aagtacaaat gtgtatttaa ttttatccat aatattatca ttgtgtattt tggtaaaacg
    11221 tgaaacaata tctttataag catttcttct tatgtcttct atccctggcc tatctttaat
    11281 gaccttttct tcaactattg tatttaatat aacttgaatt agacccagta taatatcttt
    11341 gttgtatcct tttcttattc tatttgtaag atatttttta actatatccc aatctacata
    11401 ctttcttcta gcacctgcaa ttattgcaaa atatagacct atttcttttg aagagtaatc
    11461 tttttctgat atatctatac tttcattgta atcaccagct attgtccatg ataagttatt
    11521 agctctattt tcaaattcat aatcatcata tatccatttc ataatctcac ctatattaaa
    11581 tatgacttat tggaaacaca tctatactct cccatttatt aggtattcta gttttaatta
    11641 catctccaac catttctttc tcatatacat caaaagtctt tcctgtaagt cccatattaa
    11701 ttgcaagagt tggttttaat cctcttctta tagtcttaag agatgccata agaccacgta
    11761 aatcaatagc tttactagat atctctccat tttgagactt caattgtaaa tctaaaaata
    11821 ttcctgcaaa gtgtattagt ttttcttcat cagcatctga aaattcattt tttaaaatca
    11881 tcattaactt atcttcttct ataggaggaa tatctattac cataaatcta gataccagtg
    11941 cttcattaag ttcttttgtt cctgcatatt cataattcat agtcccaata aatcttgttg
    12001 ctggatgtag attgactctc tcatacccag gtacatcaat tattcttcta tagtctaaag
    12061 ctgaatgtac cacaactata gcatcatttt ttgccatatt aatttcatca aacaccccaa
    12121 aacctccatt aatagcacac tcataaactg agcctcttct aagtttaact tcattgtcta
    12181 taaatgtatc tgtacctata agtgttgaac tgtctgtatt tatatgaaat gatgtattcc
    12241 actgaggtct attaaatatt tcccctagat tatcagcaag taagtttttt cccgttgcct
    12301 ttggtcccga taataatata ttttcttctt ctaaaatagc tgctatacac atagacaaga
    12361 tatctttacc ataaaaataa gttttagact ttgttactct gtattctaaa tctttttcta
    12421 atccataata atttctaaaa tacagtacat cttcaataag tttttcatct accccttgca
    12481 cccttagatt atctattata tccatatttt tacccctttt atataaatag tatttgtttc
    12541 atttcttatc accattttag cataaaagga tataagctaa aattgatttt ttaatctccc
    12601 ccattttaag taaaaccatg caccatttta tcactacaaa attaagagta ctacttactg
    12661 atatttcttg attttattcg tctatacgta tataatatat actgataaat tatgaggaaa
    12721 ggatgattga aatatggaat atatgtcttg cccagaagta gcaaaaaaat ggggtatttc
    12781 tgaaagaaga gtacaaaaac tatgtgaaga aagtcgcata ccaggagttt caaaactcgg
    12841 gtatatgtgg ctgataccaa agaacgcaga aaagcctgtt gatggtagaa caaaaagaag
    12901 aaaggaagta caatatgaat agcgttttga ttatagatga tgacaaagaa ctttgtgctc
    12961 ttatgaaaaa atgtgttgag caagaaaatt tatctgctat tactgcacat ggtggtgcag
    13021 aaggtctaca tttagtcgat aaaaatagac acacactctc tcttgtaatt ttggacataa
    13081 tgatgccaga tatagacggt tttcaagttc tgaaaaaaat tagagaaaca agtaatattc
    13141 cagtaattat gcttactgct aaaaatgacg aggatgataa agtttccgga ctacgtttag
    13201 gtgctgacga ttacctaaca aaaccgttca gcataaacga acttatggct cgtgtcaatt
    13261 ctcttattcg tcggtatact atgctaaacc ctgcttttat aacagacaca gatttcataa
    13321 taataaatgg catgattatt gacaagacaa accgaattgt ttctgtcaat aatattcctg
    13381 ttcaacttac aagcaaagaa tttgatttac ttgcttttct ggcttctaat aagggacggg
    13441 tgtttaccaa aaaacagatt tatacacaag tatgggaaga agaatatgct tttgacgata
    13501 gtaacatcat gtctttcatc agtaaattga gaaaaaagat tgaaccagac cccaaccatc
    13561 cattttatat tttgacagtt cgtggtgtcg gttatcgttt taataaggag gcttaacatg
    13621 aatacaagtg tctatctgct tttgatattg gctcttagcc tgattattat agcgtacctt
    13681 gtttctgtcc tgctacgtgt ccgaatacaa cttacactta taaaagatgc tttagaggat
    13741 ataaaaaatg gaaaccttaa tcgacgtatt ttaacagatg aaaacgacat tacaaaacaa
    13801 atttgctatg atattaacga aatagcaatc aatagccaat ttcaacttat tcagcaaaaa
    13861 caatcagaac aagcctacaa acagctaatg acaagtctct cccatgatgt aaaaactcca
    13921 cttgcttctt tggtcggtta tttggaagca gtagaaagta aaattgttgt aggagaggaa
    13981 aaagacgagt atatccatgt tgcgtctaat aaggctcatt acttaaagaa ttttgtagaa
    14041 aatctatttg aatgggtaaa attggattct aaggaacaag tttttcattt tgatattttt
    14101 gacttgaatg aattatcccg taatattata tctgattgga tacctgtttt agaaagcagt
    14161 cattttgaat atgaatttga tataccagaa atagagtact tcttacgtat agacgcaaat
    14221 gcatataccc gtatcattaa taacctatta caaaatatta ttacccatag tagtggcaac
    14281 aaaatgacat tgagaatttt tgaaaacaaa gagcaagctc aaattataat aacagataat
    14341 gggaaaggta tatcttcaga caatctccca catatttttg aaaggttgta ccaatgcgac
    14401 cattcacgag cttcaaaggg aaatggttta ggcttggcga ttgcaaagga acttattaac
    14461 gctcataagg gaaatattac cgccaacagc actcccggta tgggaacaga atttacaata
    14521 ttgcttccta aagccctgta aaagtacgag gctttcttac tctaaaacaa gataaaagca
    14581 agattatggc aaggttttgg caaggttcat gttttataat tctaattgta gttgattttg
    14641 acgttgtatc aactatcttt tgtagaaaca aatttattaa aagtgaggaa attatatatg
    14701 aatgattttg tgattgaaac aaagcaactt acaaaaattt atgggaatca aacagtagtt
    14761 gacaaagtca atctccatgt aaaaaaaggc cgaatatatg gtctgttagg acgcaacgga
    14821 gctgggaaaa ccacaattat gaaaatgatt ttaggattga cttcaatcac gtatggcgag
    14881 gtagatgtat ttggagagaa tattaaggga cgtgaaaaac aagtatatcc ccgtatcggt
    14941 gcaattatcg aaacgccagg attttatcct aatctgacag gaacggagaa cttggagatt
    15001 tttgcaaaac tgcgtggtac agccgcccct aattctgtaa aaagagcatt ggaaattgta
    15061 ggcttacctt ataaaaataa aaagctgttt agtaaatatt cacttggcat gaaacagcga
    15121 cttggtattg ccaacgctat cctgcatgac ccagaactgt tagttttaga tgagccaacc
    15181 aatggtcttg accctattgg tattgcggag atgagaaagt ttattaggga cttgagcgtt
    15241 gagcatggaa agacaattct tatttccagt catattcttt cagaaatctc attgttggct
    15301 gatgatattg gaattatcga ccacggtgtt cttttggaag aaagtagtat gagtgaacta
    15361 gaaaagaaaa acagtaaata tatcctgcta caagtttcag atattccgaa gacatcactt
    15421 attttagagc gtcaatttaa cacgaaggat tattccgttc aagatgacta cacgttacac
    15481 ctttataaca ctaatctgga tatgggtgaa atcaataaag cacttgtaat gcagaatgta
    15541 actgttatta gttctcaact ttgtaatgat actttagagg actactttaa aaaaatcaca
    15601 ggaggagagg gcattgctta aacttattca aacagaattt cttaaactgc gtcgtaggaa
    15661 acttatttgg ctgatgttgt tgtctgctct cattatgccg tttttcgcac tactatactt
    15721 caattatttt ggtaaaacag gtgttgagcc aataaagttt tataaatggt ctgcatttgg
    15781 ttatacactt tggattattt tgcctgttgt tttgggtata ttttgcacca tgcttataca
    15841 cgaagaaaac cagtatgata tgctcaaaca gctttggatt gtacctatta gtaaaatggg
    15901 atactttttt agtaaatttt tcgttgtttt gatttactct atttgtttta tgctgattac
    15961 agccgttgct tctgtgttat ttagtgtact ttctggatat gtcgtattta gctgggcaag
    16021 cattttatat ttgttgaaaa aatgtttaga aattggtgta atcactgctt ttgtaatgtt
    16081 gccgattttg gcaatcgcta catctcaaaa aggatacatt ctcccaattt gtatcacatt
    16141 ggtatatgcc ttttccggtt ttgttataat gacaataaat atgtatttac acccattatc
    16201 cagtatggga gttattatca tgagaaataa agacattcca ggtcttatat tttcacagga
    16261 aattaatgtc ccattagcat ttctttgtat ttgtatttgg agtattgtat cagtattgtt
    16321 tgcaaatatt gcactaggaa gaagaaagtg aggtgtagat aatgtggaaa ttactttggg
    16381 ctgaatgtca aaaaattcgt cgttcaaaaa ttgtttggat tacagttttt gcatccatta
    16441 tgatagcagt catagttttt gcaggggggc aggatgtata taatgaccca gatttacatt
    16501 atggcttaaa gagcgtttat gacggttcac ggtatataga caatgcaggt tggtatatgg
    16561 acgcagtaca accttggtca actttttttg ttcttcctgc tgtcattgcc ctattaggaa
    16621 gctatattat ttgtcgtgaa gaagaggagg acactattaa atccctgcgt cttattccca
    16681 taaatgaaac aaatttaacc atagcaaaaa tgattattac ttttatattc agtatacttc
    16741 tttatttgtt actctttact ataacatttt tgactgaatc cgttttacat ttttccgatt
    16801 tatcgacaaa attggtttta agttgcatga aagagtattt tcttgatggc ataggtgtat
    16861 tctttgcaat ttctcccatt attgccttgg tatcgcgcat gaaaaaagga tattggcttg
    16921 cattagtatt cacagaagtt tattctattg ctggactatt tgcgggtatg tcaaatgtct
    16981 tacaaacctt ttttcctatt gcggcaatat ttaatatttc tggatactat ataactactg
    17041 gagaaaaaat tatggggagt atcataagtt tattactttg tgcctgcctt tctgcattta
    17101 tacttaaagg gctaaaacac aatgaaaaaa attgaaatag gtatatcaaa atgaaaaaga
    17161 taaaaaaact gattattcta attgtattct tgtttctttt tggcatgtta cactgttata
    17221 ctgaatggaa attcaacaat aacccaccta aaggggtaat agaaagaata aatgagtgga
    17281 ctgataagat tggactggat tagtaactta tgttaattat agtgaatgta atattagcaa
    17341 gttattgttt cgtattttaa tactataact ttaaatattt ggttttaatc ttccaaacga
    17401 atataaaaaa actgtcacag aggcaacata tttttgaata tttataaagt ggtagttttg
    17461 attttcaaag ctaccgcctt ttcttctata taagcaaact tatcctcaac aaagtgtaaa
    17521 acatggtaca ttttaagaaa aaagtaccac agacacaagc aataaaagaa acgccgagaa
    17581 cctacaaaaa cgtagtgctt atgcagattt acgacgcctt ctattttctc aaccgtctta
    17641 atgaccttgt acaaaagaaa tttttctaat attttttata atcttatctt gtgatgtttt
    17701 ttatgtataa atgacttaat aacaaatcca ataaaaatta tggatattgg tataattaga
    17761 acgaggaatt tataatcatt ataatgtgac attattctta cccaactctc agaaaaaata
    17821 tatcctatac tgattaatga agtattccat atggttattc ccacgataga tgatattaca
    17881 aaagttataa tattttgccc tgctatacct gctataaaag atatgtatgt tctacataaa
    17941 gggattaatc tacatacaca aacagaaata gaagagtatt tattaaaata atcttgagat
    18001 gcaaatattc ctttctttgc ctttggacat atctctatta ttttatttat gatagattta
    18061 cctccccaat ttcccactgt ataacaaaat atcgaaccaa gtatacctgc aattatactt
    18121 aaaattaaaa ttgtcagaaa tccaaaatga tttcttgcag caattgctcc acataaaggt
    18181 aaaacaactt cgctaggtaa tggaaaacaa gcatactcaa tcataattaa tacaaataca
    18241 gagattaatc catattgtaa aataaaacta ttgattacag acacttactt atctatctcc
    18301 tttcttattt aaaggtttta agggtacatg ttctaaggat tctcacccta tatttaaaga
    18361 atcaatctct ttaaactatt atatgtattt acacaaagca tttataacat actttaaaaa
    18421 tagtacctta aaataagaaa cttaataaat aaaaaaagat tacgtggcta cgtcctactc
    18481 tcccaggcag tttcccacca agtaccatca gcgctagaga gcttaacttc tgtgttcgga
    18541 atgggaacag gtgtatcctc tctgctattg taaccacata atctttatgc ttaatatttc
//
LOCUS       DAFAZV010000064        18480 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFAZV010000064 DAFAZV010000000
VERSION     DAFAZV010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18480
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.064"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..2916
                     /locus_tag="KOU88_003464"
     CDS             <1..2916
                     /locus_tag="KOU88_003464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBK3213297.1"
                     /translation="LSCIFQLFDKDNCDEDDCLKTIKENMKNDKSGYFNYNLDNEKFM
                     LNYQPLGVNDWYVFSVVPNKIVSIQSENISYDVYIFALEILLVILIFIIYIACIINNN
                     TKIIINEKEKFKVLTDNILGGVKTCLKDEYMTMTYVSQGFLELTGYSCEDLNKIFKNR
                     FKDMIYKDDLDKFNCIILNQLEKQDKIEVEYRIVRKDGSIIWILERSKSINDNKGSEC
                     IQGVLTDITELKKIQEELDSKRFEIQAINDSIVGGIVITEINDDFDSIYLNEGYLNMI
                     GYTRKQLKDELNNKLIKLIFKDDRTELINSINKQLKLSDTFASEQRVEKRDGTIIWIL
                     LKGRKMIYENGKSVLCCVIVDITSAKLLEQELKKSEERHEIILKQTQNIIIEWDIEKD
                     KMNISPNWYNKFKYDPITENATKNIIKSADIYHDDMDKFISLIKLTSQGSEYEECEIR
                     LRTRDTIYAWFSIKATTLFDNNGKPYKVVGSLTDIDESKREAEKLKERAEKDPLTDLY
                     NKKASQSLIEEYITLDKKRKGALMIIDIDDFKGINDNLGHLYGDAVLSEIANDLINLF
                     RATDIVGRIGGDEFIVFIKDISETRDIINKAEELVKTFERSFLGKGRNYKISLSVGIA
                     KFPQDGMDYMTLFRNADMALYSAKGKGKNCYTLYDKKIDKVQYITNTRNAGDSDNVEM
                     SFKEHITNYIFDILYESSDIEVAVNLILSIVGKHFNVSRMYIFENSDDNRVCKNTFEW
                     CNEGVTSEINNLKNICYKDLGNYLLNFNADGLFYCNDIENLGSDVKKVLKPQGIRSIL
                     QCKILEGNEFRGFIGFDECSYNRMWTNDEVNTLTFISKTLSMFLLKMRIQSKLEESLT
                     IQKSVMDNMDIWAYVVDRNTYELLFINKKMLESAPITHVGDLCYKAIWNNQDKLCKKC
                     PMIYLKDGDDTYKSFMHNKKFEVQANITTTTLKWFDGKDACLIFGSEITSIEAEENT"
     gene            3101..5035
                     /locus_tag="KOU88_003465"
     CDS             3101..5035
                     /locus_tag="KOU88_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBK3213298.1"
                     /translation="MENKFLPISKQDMIDRGWEELDFVLVTGDAYVDHHSFGTAIISR
                     VLESAGYKVGIIAQPDWRTTDDFMKLGKPRLAFLVNAGNMDSMVNHYSVSKKHREKDM
                     YSPGGKMGYRPDRATIVYCNKIREAYSDVAIVIGGIEASLRRFAHYDYWSDKVRKSML
                     IDSGADLLVYGMSEKQIVEVANALNDGYDPKYIRHIDGTCYISDTLEEIYDKYILIPS
                     YKEICEDKMKYVEAFKIQYDEQDPFRGNIIVQPHGSKYLVQNKPEKPLSREELDEVYG
                     LPYQKTYHPVYEKFGGIPAIEEVKFSIVSSRGCFGSCSFCAITFHQGRAVQSRSEKSI
                     IYEAIGITNLDDFKGYIHDVGGPTANFRRPACKKQITKGACKNRQCLSPSPCKNLDAD
                     HSEYLHLLRAVRKLPKIKKVFVRSGIRYDYVMEDKNNKFLRELIEHHVSGQLKVAPEH
                     ISEEVLKYMQKPAGKTYDKFRQKFFAINEELGKKQYLIPYLMSSHPGSTLNSAIELAE
                     YLRDTHYQPEQVQDFYPTPGTLSTTMFYTGIDPLTMKPVYVPKSKRDKAMQRALLQYR
                     APRNYDLVYSALVEAGREDLIGFGHRCLIKPKNEKPYFNRNNSKKNVSKGINKNKKTN
                     TNNRSNKNQQKSSTKKKKKH"
     gene            5141..6136
                     /locus_tag="KOU88_003466"
     CDS             5141..6136
                     /locus_tag="KOU88_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK3213299.1"
                     /translation="MKKYISIILLVVLTMVVLVGCSPGKDNPKNKELSVVKQVKVAVP
                     DGLPAVAIAKLANENPEIKEGYETVYSIEKTPEAISTRVMKKDADIAIVPSNMAAIAY
                     NKTSSYNIVGTVGMGSLYLVSTENIKDYSDLVGKEVGCTGKGLTPDITIKSLLLQKDI
                     NYSDIKFNYVNSASELVPLLATGKVKTGIVPEPALSALMSKNPDIKIIKSLNDSWKEV
                     SGSKDGYPQSTLIVKSEFLRDNKDFVDSFVGQLSNSIDWANKNPEELGAYSEKIKIST
                     ESKIIGKSLERANLKYIPVKDMIKDYKNYYEKLANFDDKTLGGKVPDEAIYFVEK"
     gene            6108..6893
                     /locus_tag="KOU88_003467"
     CDS             6108..6893
                     /locus_tag="KOU88_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK3213300.1"
                     /translation="MKQYTLLRNKKNKEQFIDKMEVTLSCVILLFLWQIIALKIDNDI
                     FLPTVGQVFNSIKEIMLNSSFYIDILYSMGRCFFSFLLAMIFAIILSIVSYLNRFFRN
                     LLKPINALTRSIPTMILVVLALIWFEKDSTPFIVGFTIVFPILYDNVLGAILNIDKNL
                     LEMANVYKIRFIDKVLKIYLPAIKFQIISILVSTFSLSLKVAIAGEVYSQPTYGIGTM
                     IQTEKINFNTSGIFAWIIIVLLISAILQIAQKFLARRAFLWKR"
     gene            6881..7579
                     /locus_tag="KOU88_003468"
     CDS             6881..7579
                     /locus_tag="KOU88_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213301.1"
                     /translation="MEKIKLSIENINKRYDSRIIFRDFNIDFYVNEVNCILGKSGCGK
                     TTLLNIISGIIKNDTNNLNIKENLNRVGNKLKASYIFQDDRLIDWLTVEENIKIVVNK
                     YYNKTQLNKICDEYLELVGISDYKKFYPQMLSGGIRQRVNIARAFIYPSKNIIMDEPF
                     KSIDAKNTQLIMDNFRNILRKEKRTVLFVTHNIEEALFLADRIFILGDSPIRIKKILK
                     NSKELEKNEVLKLI"
     gene            7702..8175
                     /gene="ybaK"
                     /locus_tag="KOU88_003469"
     CDS             7702..8175
                     /gene="ybaK"
                     /locus_tag="KOU88_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBK3213302.1"
                     /translation="MVKTNAMRILDSNKIDYKVMSYEVKSEHVDGVEVAHDIGRDVNE
                     VYKTLVTQGVSKNIYVYVIPVHENLDLKKAAKVAKEKSVEMIHVKDINKLTGYIRGGC
                     SPIGMKKLYKTFVNESAKNLDTIIVSAGKIGYQIELSPFDLQRLIKVEFVDVIKK"
     gene            8372..9211
                     /locus_tag="KOU88_003470"
     CDS             8372..9211
                     /locus_tag="KOU88_003470"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase"
                     /protein_id="HBK3213303.1"
                     /translation="MRKIKSEQIVEQVKKLCIEASLYLGEDVLSCIKEKAKSEKSEVG
                     KNILNILVENAEIAKEKNIPICQDTGMAVFFVEIGQEVLIEGDTLTDAINEGVRQGYE
                     EGYLRKSVVSPINRVNTKDNTPAVIHYDMVKGDKIKIEFAAKGFGSENMSKMKMLKPS
                     DGLEGIKKFIIDTVSEAGPNPCPPMVIGVGIGGTVDKCAQIAKKALFRELGEFNKDEN
                     IAKLESELLTAINKLGIGPQGLGGTTTALGLNIETFPTHIAGLPVVVNINCHASRHKK
                     VVI"
     gene            9224..9772
                     /locus_tag="KOU88_003471"
     CDS             9224..9772
                     /locus_tag="KOU88_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S-containing hydro-lyase"
                     /protein_id="HBK3213304.1"
                     /translation="MIKITTPVNEIDIAKLNCGDTISLSGILYTARDAAHKRLIDCIN
                     KGEELPFDVYGQGIYYVGPTPTKPGEVIGAAGPTTSYRMDDLTIPLLERGLRLMIGKG
                     KRSDEVIEGMQKYGAVYLAAIGGAGAYISNSIKSCEIIAYEDLGAEAIRKIVVEDLKL
                     TVAIDSYGNNIYEQGRAIYECK"
     gene            9838..11019
                     /locus_tag="KOU88_003472"
     CDS             9838..11019
                     /locus_tag="KOU88_003472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBK3213305.1"
                     /translation="MSKDYAKLALEMHEINKGKVSVESKVEIKTKDDLSTAYTPGVAE
                     PCLKIHENQDDVYRYTSKGNLVAVVSDGSAVLGLGNIGAEASIPVMEGKAILFKQFAD
                     VDAFPICLKTNDVDEIVKSVELMEPVFGGINLEDISSPRCFEIEERLKKSLSIPVFHD
                     DQHGTAIIVAAAIINSIKLIENKKIEDLEIVINGAGAAGIAIAKILLNMNVKNIILCD
                     RSGALEASIENLNYVQREMLKVTNIRNEKGPLKDIIKGKDVFIGVSGPGAVTKEMVES
                     MSEKPIILAMANPTPEIMPEEAKLGGAFIMGTGRSDFPNQVNNVLAFPGIFRGALDVK
                     AKEINEEMKIAAAYAIANTISDEEICPEYILPDVFNKNVVKNVAKAVKEAAIKTKVNR
                     I"
     gene            11314..11700
                     /locus_tag="KOU88_003473"
     CDS             11314..11700
                     /locus_tag="KOU88_003473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009248914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3213306.1"
                     /translation="MEYKVNDQELNASMFIPFVNRIWPGDYNMDKTQTALSKTLNITA
                     YDDKVLVGCLRVLSDGYYFGTITELLVLPEYQKQGIGSKLFQLAKENTPTMLYFGAQP
                     GVEEFYEKNGCQRSLQSYIIKKKDSY"
     gene            11850..12113
                     /locus_tag="KOU88_003474"
     CDS             11850..12113
                     /locus_tag="KOU88_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK3213307.1"
                     /translation="MEETKFCQCCAMPMGQTDELYGTNKDGSKSTDYCSYCFKDGEFT
                     ADISMEEMIEVCIPHMLQSNKDMTEDEARTMMNNFFPTLKRWK"
     gene            complement(12242..13084)
                     /locus_tag="KOU88_003475"
     CDS             complement(12242..13084)
                     /locus_tag="KOU88_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBK3213308.1"
                     /translation="MINIGDFNKLTVKRKTEFGYFLDGQTNNTKDDILLHNRLIGKNE
                     INIGDEVNAFIFKDSDDRTAATLIPPLAKVGDVAHLKVVDNTDIGTFIDMGLPKDILV
                     PFKAKTYPLFRDEKYLFYIYLDKSKRIAATTDIDSYLLTDHTYNVGDIVTGVVYGFQT
                     NNSAMICVDNKYAGVILHNEYFTELKTGDVLENLHVIKIYEDGKLGLSPRGNRKDELD
                     TLENKILSYLEGSDGYMRFNDKSDPKDISILFNSSKKNFKRALGVLMKKGLIYQDEEG
                     TYLK"
     gene            13379..14113
                     /locus_tag="KOU88_003476"
     CDS             13379..14113
                     /locus_tag="KOU88_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3213309.1"
                     /translation="MKIVNKSSNIPLHTQLSSIIREMIETGELKEGDAIMPERELCNI
                     QNVSRMTVNKTIVGLVTEGLLYRVQGKGTFVAKQKKKYQFSNVKGFTDVMKEKGVNIK
                     TDILSFEMELPDDLVKRKLGISDNTTNIYKIVRLRYTDGEPFGLEIVYLSEEMCKGLT
                     KGILDNSSLYRVLNEKYGYKIQKAEQVMEPVILSDEESKLLETDEGALALKLHRNSYN
                     REGSPIEYTISIFRTDKYQYEIVLSE"
     gene            14123..15256
                     /gene="nagA"
                     /locus_tag="KOU88_003477"
     CDS             14123..15256
                     /gene="nagA"
                     /locus_tag="KOU88_003477"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBK3213310.1"
                     /translation="MKCLINGKIILKNQILENKVLVFDEKIIDIADSVPKDCEVIDAD
                     GKYISPGLIDIHIHGNMGKDTMDSTDESIETISKSIMRHGVTSFLPTTMTMDKEHVYD
                     ALEVIKKAQNRKLEGAQVLGAHLEGPFINENYKGAQNEKFIINSKYEFIKEYKDVIKV
                     ITYAPEKDIDFDFTREIKRCTDIVLSIGHSNANYDQAKEAINLGVTNVTHMFNAMTGL
                     NHRDPGVVGAALTTNVYSELIADTIHINKDLFQFILNNKGKERLILITDSIEAGGLED
                     GNYSLGGQKVIVKGNEARLENGALAGSVLSLNKMVFNFLDNTNLKVNEAINLASLNPA
                     TSLGINDKKGSLEIGKDADIAVFDENLDCKMTLCLGDVVYKNI"
     gene            15355..16104
                     /gene="nagB"
                     /locus_tag="KOU88_003478"
     CDS             15355..16104
                     /gene="nagB"
                     /locus_tag="KOU88_003478"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012425552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBK3213311.1"
                     /translation="MRVLVCKDYDGMSKKAAEMIAAQIVLKPNSILGLATGSTPVGMY
                     RDLVKKYNDNIVDFSDVMSFNLDEYYKLPISNDQSYDYFMKENLFNHVNIKPENTHLP
                     NGMADDIEKECMNYEASIDAAGGIDVQVLGIGRNAHIGFNEPDTKFAKRTHVVELTES
                     TIEANARFFKSREDVPKKAVSMGIGSILKSKKILLLASGEEKADAVYNTVYGDITPEV
                     PGSILQLHKDTIVIVDEAAASKLNPKDYKLV"
     gene            16279..16551
                     /locus_tag="KOU88_003479"
     CDS             16279..16551
                     /locus_tag="KOU88_003479"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213312.1"
                     /translation="MLKIIMFSGILSSIIKLPIIGILPTGNIKKNTGISDSKKDGKQR
                     RSNLGISIYQLPSFLYSLINNSVPSNKPIPPEEIKLIKMYLLKSCI"
     gene            17211..17915
                     /locus_tag="KOU88_003480"
     CDS             17211..17915
                     /locus_tag="KOU88_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213313.1"
                     /translation="MSKLIYIADDEDNIRNLVKTFLKNEGHDVMDFKTGDELLEQFNI
                     KECDLVILDIMMPGSSGFEVCTKLREKSTVPIIMLTARDTDIDYITGITLGSDDYFTK
                     PFSPMSLVMRVKSIFRRIEFEKKQNYDKYSNSIDMELKFGDVIINKKNKIVTSKNVNI
                     DLTPNEYNLLTYLFENIDRAVSRDELLNKIWGYDIEVETRAADDTVKRLRKKILNTNI
                     LIETVWGFGFRLKEKS"
     gene            17917..>18480
                     /locus_tag="KOU88_003481"
     CDS             17917..>18480
                     /locus_tag="KOU88_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK3213314.1"
                     /translation="MKNGNDKNRIGKIKSKFKLKFSKKNISIKTRILLSILCLIIIVF
                     MIILVSFNVFLDTYIKTTANEELTKSTEIVEHMDSNFRPIKPPQDDGKLPPKVLSNFM
                     RNVQDKVRMAETQSDADAMVVDSKYNLIFPTREDDFLKNVDEMELIRECIQNEKLDLN
                     SDENTRISTRNKDYYISTVKITSIYGEQ"
BASE COUNT         7403 a         1946 c         3255 g         5876 t
ORIGIN      
        1 ctatcatgta tatttcagct ttttgacaaa gataattgtg atgaagatga ttgtctaaaa
       61 actataaaag aaaatatgaa aaatgataag tctggatatt ttaattataa cttagataat
      121 gaaaaattta tgttaaacta tcagccactt ggagttaatg attggtatgt tttttctgtt
      181 gtgccaaata aaatagtatc tattcagtca gagaatatat cttatgatgt atatattttt
      241 gcattagaaa tactactagt tatattgatt tttataatat atatagcatg tattataaat
      301 aataacacta aaattattat aaatgaaaaa gaaaaattta aagtactcac tgataatata
      361 ctaggagggg ttaaaacctg tttaaaagat gaatatatga ctatgacata tgtaagtcag
      421 gggtttttag agcttacagg ttactcttgt gaagatttaa ataaaatatt taaaaataga
      481 tttaaagata tgatttataa agatgattta gacaagttta attgtattat tctaaatcaa
      541 ttagaaaaac aagataaaat tgaagttgaa tatagaattg taagaaaaga tggaagtata
      601 atttggattt tggagagaag taagtctata aatgataata aaggaagtga gtgtattcag
      661 ggagttttaa ctgatataac agaacttaag aaaatacaag aagaattaga ttcaaaaaga
      721 tttgaaatac aggctatcaa tgatagtatt gttggtggaa tagtgataac tgagataaat
      781 gatgattttg atagtatata tttaaatgaa ggttatttaa atatgattgg atatacacgc
      841 aaacaactga aggatgagtt aaataataaa ttaatcaaac ttatttttaa agatgataga
      901 acagaattaa ttaatagtat aaacaaacaa ctcaaattaa gtgatacatt tgcatctgaa
      961 caaagagttg aaaaaaggga tggcactatt atatggattt tattaaaagg aagaaagatg
     1021 atttatgaga atggaaaatc tgtactttgt tgtgttattg tagatattac ttctgctaaa
     1081 ttattagaac aagaacttaa aaagagtgaa gaacgtcatg aaattattct aaagcagacg
     1141 caaaatatta taatagaatg ggatatagaa aaagataaaa tgaatatatc acctaattgg
     1201 tataataagt ttaaatatga ccctataact gaaaacgcaa caaaaaatat aattaaatca
     1261 gcagatatat atcatgatga tatggataag tttatttcat taattaaact tacttcacaa
     1321 gggagtgaat atgaagagtg tgaaattaga cttagaacta gagatactat ttacgcttgg
     1381 tttagtataa aggcaacaac tttatttgat aataatggta aaccttataa agtagtagga
     1441 agtttgactg atattgatga atcaaaacga gaagctgaaa agttgaaaga aagggcagaa
     1501 aaagaccctc ttacagattt gtataataaa aaagcatcac aatcacttat agaagagtac
     1561 ataacattgg ataaaaaaag aaaaggtgct ttaatgatta ttgatattga tgactttaaa
     1621 ggaataaatg ataatttagg acatttatat ggggatgctg tattaagtga aattgcaaat
     1681 gacctaataa atctatttag agcaaccgat atagtaggaa gaattggtgg agatgagttt
     1741 attgtattta taaaagatat ttctgaaaca agagatatta taaataaagc agaagaattg
     1801 gtaaaaacat ttgaaaggtc ttttttaggt aaaggacgaa attataaaat atcattaagt
     1861 gtaggaattg ctaagtttcc acaagatggt atggactata tgacactatt tagaaatgcg
     1921 gatatggctc tttactcagc caaagggaag ggtaagaatt gttatacatt gtatgataaa
     1981 aaaattgata aagtccaata tataactaat acaagaaatg caggagatag tgataatgta
     2041 gagatgtctt ttaaagaaca tatcacaaat tatatatttg atatactata tgaatcaagt
     2101 gatatagaag tggcagtaaa tttaattcta agtattgtag gtaaacactt taatgtgagt
     2161 cgcatgtata tatttgaaaa ttcagatgat aatcgagtat gtaaaaatac atttgaatgg
     2221 tgtaacgaag gtgtaacctc ggaaattaat aatcttaaaa atatttgtta caaggattta
     2281 ggcaactatc ttttaaattt taatgcagat gggttatttt attgtaatga tattgaaaat
     2341 ttaggtagtg atgtgaaaaa agtacttaag ccacaaggca tacgttcaat attacaatgt
     2401 aaaattttag agggtaatga atttagaggg ttcataggat ttgatgaatg ttcatataat
     2461 cgtatgtgga ctaatgatga agtgaacact ttgacattta tatctaaaac gctcagtatg
     2521 tttttattaa aaatgcgtat tcagagtaag ctagaagagt ctttaacaat tcaaaaatct
     2581 gtgatggata atatggatat atgggcatat gttgttgaca ggaataccta tgaattacta
     2641 tttatcaata aaaaaatgct tgagtcagca ccaatcactc atgtaggtga tttatgttat
     2701 aaagcgatat ggaataatca agataaactt tgtaaaaaat gccctatgat atatttaaaa
     2761 gatggtgatg atacttataa atcattcatg cataataaaa agtttgaggt acaggcaaat
     2821 ataactacaa ctactttgaa atggtttgat ggtaaagatg catgtttaat atttggaagt
     2881 gaaataacta gtattgaagc tgaagaaaat acttaaaata ctgtgttata tatatactta
     2941 aaatcgcaat ttgaatttat tagacttaaa atgtctatat aaatcattta agttgtggtt
     3001 ttaagtattt tttatgatat aattaagcgt taagaacaaa attaaaagat acttttgtat
     3061 aaaaaaatat ttgttaaata tatattgagc aggtgataat atggaaaata agtttttacc
     3121 aataagcaaa caagatatga tagatagagg atgggaagaa ttagattttg ttctagttac
     3181 aggagatgct tatgtggacc atcatagttt tggaacagca ataatatcta gagttttaga
     3241 aagtgctggg tataaagttg gaataatagc tcaaccagac tggagaacta cagatgattt
     3301 tatgaagcta ggaaaaccta gacttgcatt tctagttaat gcaggaaata tggattcaat
     3361 ggtcaatcat tattctgtaa gtaaaaagca tagagaaaag gatatgtatt ctccaggtgg
     3421 gaaaatgggt tatagaccag atagagctac tatagtatat tgcaataaaa taagagaagc
     3481 atacagtgat gttgcaatag taataggtgg aattgaagcg agcttaagaa gatttgcaca
     3541 ctatgattat tggagtgata aggttagaaa gtctatgtta atagatagtg gagcagattt
     3601 attagtttat ggtatgagtg aaaagcagat tgtagaagta gccaatgcac ttaatgatgg
     3661 atatgaccca aaatacatta gacatattga tgggacatgc tatatttcag atacattgga
     3721 agaaatatat gataaatata tattaattcc atcatataaa gaaatttgtg aagataaaat
     3781 gaagtatgta gaagctttta aaattcaata tgatgagcaa gacccattta gaggtaatat
     3841 aattgttcaa cctcatggaa gtaagtatct ggttcaaaat aagccagaaa aaccacttag
     3901 tagagaagaa ctagatgaag tatatggatt accatatcag aagacatacc atcctgtgta
     3961 tgaaaaattt ggaggaatac cagctataga agaagtaaaa tttagtatag taagttcaag
     4021 aggctgtttt ggtagttgtt cattttgtgc aataacattt catcaaggta gagcagtgca
     4081 aagtagaagt gaaaaatcaa ttatttatga agcaatagga ataacaaatt tagatgattt
     4141 taaagggtat atacatgatg ttggaggtcc aacagctaat tttagaagac cagcatgtaa
     4201 aaaacaaatt actaaaggtg cttgtaaaaa tagacaatgc ttatctccat caccatgtaa
     4261 aaatttagat gcagaccaca gtgaatactt acatttactt agagctgtaa gaaaattacc
     4321 taaaataaaa aaggtgtttg tgcgttctgg aattagatac gattatgtaa tggaagataa
     4381 gaacaataaa tttcttagag agttgataga gcatcatgta agtggtcagt taaaggtagc
     4441 cccagaacat atatcagaag aagttttaaa gtatatgcaa aaaccagcag gaaaaactta
     4501 tgataaattt agacagaagt tttttgctat aaatgaagaa ttaggtaaaa agcaatattt
     4561 gataccctat ttaatgtcta gtcaccctgg ttctacctta aatagcgcta tagagttagc
     4621 agagtattta agagatactc actaccaacc agagcaggtt caggattttt atccaactcc
     4681 agggactcta tctacaacca tgttttatac aggtattgac ccgcttacaa tgaagccagt
     4741 ttatgttcct aaatcaaaac gtgacaaggc aatgcaaagg gctttattac aatatagagc
     4801 acctagaaat tatgatttgg tatactctgc gttagttgaa gcaggaagag aagacttaat
     4861 tggttttgga catagatgtc ttataaagcc aaaaaatgaa aagccttatt ttaatagaaa
     4921 taattctaaa aaaaatgtat ctaaaggaat aaataaaaac aaaaaaacta atacaaataa
     4981 cagaagtaat aaaaatcaac aaaaaagttc aactaaaaaa aagaaaaaac attaaagtat
     5041 aaataaaaat acttaaaaaa gaaggattat tcgataaatt aacagaaatt agtataaata
     5101 aatataatta ttttaatgac gttacctttg ggaggaagag atgaaaaagt atatttctat
     5161 aatattatta gtggtgttga ctatggttgt tttggtagga tgttcaccag gaaaagataa
     5221 ccctaaaaat aaggagctat cagttgtcaa acaagtaaaa gtagctgttc cagatggact
     5281 accagcagtg gcaatagcta aacttgcaaa tgaaaatcca gagattaaag aaggatatga
     5341 aacagtgtat agcattgaaa agacacctga ggcgatttcc actagagtga tgaaaaaaga
     5401 tgcagatata gctatagttc cttcaaacat ggctgcaata gcgtataata aaacttcatc
     5461 atataatatt gttggaactg taggaatggg ttcactttat ttggtgtcaa cagaaaatat
     5521 aaaagattac tctgatttag ttggtaaaga agttggatgt actggaaaag gacttactcc
     5581 agacataact ataaaaagtc ttttgttaca aaaggatata aattattcag atataaaatt
     5641 taattatgta aattcagcaa gtgaactggt accattattg gctactggta aagttaaaac
     5701 aggtattgtt ccagaacctg cacttagtgc tttgatgtct aaaaatccag acataaaaat
     5761 tataaaaagt ttaaatgact catggaagga agtaagtggt tcaaaagatg gttatcctca
     5821 atctacttta attgtaaagt ctgaattttt aagagataat aaagattttg ttgattcttt
     5881 tgtaggtcaa ttatcaaata gtatagattg ggcaaacaaa aatcctgaag aattaggtgc
     5941 atattctgaa aaaataaaaa tatctactga atcaaagata ataggaaaat ctcttgaaag
     6001 agctaattta aaatatattc cagttaagga catgattaaa gattataaaa attactatga
     6061 gaaattagct aattttgatg ataagacatt aggaggcaaa gtaccagatg aagcaatata
     6121 ctttgttgag aaataaaaaa aataaagaac aatttataga taaaatggag gtaacacttt
     6181 cttgtgttat cctcttattt ttatggcaaa ttattgcttt aaaaattgat aatgatattt
     6241 ttttaccaac agtaggtcaa gtatttaata gtataaaaga gattatgcta aattctagtt
     6301 tctatataga tatactttac tctatgggga gatgtttttt tagtttttta ctggctatga
     6361 tttttgctat tatactttca atagtgtctt atttaaatag attttttaga aacttattaa
     6421 agccaatcaa tgctttgaca cgttcaatac caactatgat attggtagta cttgcactta
     6481 tttggtttga aaaggatagt acccctttta tagttggatt tactatagtt tttcctatat
     6541 tgtatgataa cgttttgggc gctatattga atatagacaa gaacttatta gaaatggcta
     6601 atgtgtataa aataaggttt atagataagg tgttaaaaat ttatttacca gccataaaat
     6661 ttcaaattat atctatacta gtatcaacat tctctttaag tttgaaagtt gctatagcag
     6721 gagaggtata tagtcaacct acatatggta ttggaactat gatacagact gaaaaaatta
     6781 actttaacac atctggaata tttgcatgga taattattgt tcttttaata tctgctattt
     6841 tacaaatagc tcaaaagttt ttagcaagga gagctttttt atggaaaaga taaagttgag
     6901 tattgaaaat ataaataaaa gatatgatag tcgtattata tttagagact ttaatattga
     6961 tttttatgta aatgaggtaa attgtatcct tggaaaatct ggttgtggaa aaactacact
     7021 cttgaacata ataagtggga ttattaaaaa tgacaccaac aatctaaata tcaaagaaaa
     7081 tttaaatcga gtaggaaata agcttaaagc tagttacata tttcaagatg atagacttat
     7141 agactggtta acagtagaag aaaatataaa gatagttgta aataaatact ataataaaac
     7201 tcaattaaat aaaatttgtg atgaatactt ggaattggtt ggaattagtg attataaaaa
     7261 attctatcct cagatgctta gtggaggtat tagacaaaga gtaaatattg ctagagcttt
     7321 tatatatcca tcaaaaaaca ttataatgga tgaacctttt aaatctattg atgcaaagaa
     7381 tacacagctt ataatggata atttcagaaa tatattaaga aaagaaaaga gaactgtgtt
     7441 atttgtaact cataatattg aggaagcatt gtttttagca gataggatat ttattttagg
     7501 agactctcca attagaataa aaaaaatatt aaaaaattct aaggaattgg aaaaaaatga
     7561 agttttgaag ttgatataga gttataataa tactgtcgtt ttaaaatata tttggttaaa
     7621 atctataaga ctatattaaa atagtacaga atattcaaaa ctgtgtataa tgttcgtatt
     7681 ttataaaaag gaagtgaatg tatggttaag actaatgcta tgagaatatt agattcaaat
     7741 aagattgatt ataaagtaat gtcttatgaa gtgaaaagtg aacatgtgga tggtgttgag
     7801 gtggcacatg atataggaag agatgtaaat gaagtgtata agacattagt aactcaagga
     7861 gttagtaaga atatatatgt atatgtaata ccagtacatg aaaacttaga cttaaaaaag
     7921 gctgcaaaag tagctaaaga gaaaagtgta gagatgattc atgtaaaaga tataaataag
     7981 cttacaggtt atattagagg cggatgttct cctataggta tgaaaaagct ttataaaact
     8041 tttgtaaatg aaagtgcaaa gaatttagat acaattattg tgagtgcagg aaaaatagga
     8101 tatcaaatag aactatctcc atttgattta caaagactta taaaagtaga atttgtagat
     8161 gtaataaaaa aataagaatt acatataaaa tatagagctt atattcttaa taataggtgt
     8221 tgtagtatta ataaaatgaa taataatttt aaaataaata ttcagttact tatgtgtaat
     8281 tggtataaaa atattgagaa attttaaaaa caatggtaaa gtgtaagtat aatcacgaat
     8341 attttttata aagtaatgga gggatgttcg cttgagaaaa ataaaatctg aacaaatcgt
     8401 cgagcaggta aaaaaacttt gtatagaagc gagcctatat ttaggagaag atgttttaag
     8461 ttgtataaaa gaaaaagcga aaagcgaaaa gagtgaagtt ggaaaaaata tattgaatat
     8521 attagttgaa aatgctgaaa tagctaaaga aaaaaatata ccaatatgcc aagatactgg
     8581 tatggctgta ttttttgttg aaataggaca agaagtttta attgaaggag acacacttac
     8641 tgatgctata aatgagggag taagacaagg gtatgaagaa ggctacttaa gaaaatctgt
     8701 tgtaagtcca attaacagag taaatacaaa agataataca cctgctgtta ttcattatga
     8761 tatggtaaaa ggtgataaaa ttaaaataga atttgcagct aagggatttg gaagcgaaaa
     8821 tatgagtaag atgaaaatgt taaagccatc agatggattg gaaggaatta aaaaattcat
     8881 aatagataca gtttcagaag ctggacctaa cccatgtcct cctatggtaa ttggagttgg
     8941 tataggtggg actgtggaca aatgtgctca aatagctaaa aaggcacttt ttagagaact
     9001 aggtgaattt aataaggacg aaaatatagc aaaacttgaa agtgaactat taacagctat
     9061 taataaactt ggtataggac ctcaaggctt aggtggtact acaacagctt tgggattaaa
     9121 catagagact tttcctacac acatagcagg tctacctgtt gttgtaaata taaactgcca
     9181 tgcatcaaga cataagaagg tagtaattta ggaggaaaat aaaatgataa aaataactac
     9241 acctgtaaat gaaattgata tagcaaaatt aaattgtgga gatacaatta gtttgagtgg
     9301 tatactttat acagcaagag atgctgctca taaaagattg atagattgta taaataaagg
     9361 tgaagaatta ccatttgatg tatatggtca aggaatatat tatgtaggac ctactcctac
     9421 aaagccagga gaagttatag gtgctgcagg tccaacgacg agttatagaa tggatgattt
     9481 gactatacct cttttagaaa gaggtcttag attgatgata ggcaagggaa aaagaagtga
     9541 tgaagttata gaaggtatgc aaaaatacgg agcagtttat cttgctgcaa taggaggagc
     9601 tggagcgtat atttcaaatt caataaaatc atgtgaaatt attgcatatg aagatttagg
     9661 agctgaagct ataagaaaga ttgtagtaga agaccttaaa cttacagtag caatagatag
     9721 ctatggaaat aatatatatg agcaaggtcg agcaatttat gaatgtaaat aatgtttaga
     9781 aataaatatg aatatcaaaa ttaaaaatag ttgtgtatat tttaaggagg aaaattgatg
     9841 tctaaggatt atgcaaaatt ggcattagaa atgcatgaaa tcaacaaagg taaagtaagt
     9901 gtagaaagca aggtagaaat taaaactaag gatgatttat caacagcata tacaccaggg
     9961 gttgctgaac cttgtttaaa aatacatgaa aatcaagatg atgtttatag atacacttct
    10021 aaagggaatc tagtagcagt agttagtgat ggaagtgctg tacttggatt aggtaacatt
    10081 ggtgctgaag catctatacc tgttatggaa ggtaaagcta tattatttaa acaatttgca
    10141 gatgtagacg cttttccaat atgtttaaag actaatgatg tagatgagat agttaaatct
    10201 gtagagttga tggagcctgt atttggaggt ataaatttgg aagacatatc ttctccaaga
    10261 tgttttgaga tagaagagag attaaaaaaa tctttaagta tacctgtttt tcatgatgac
    10321 caacatggga cagcaataat agttgcagca gccataataa actcaataaa gttaattgaa
    10381 aataaaaaaa tagaagattt agaaatagtt ataaacggag caggagctgc tggtattgcc
    10441 atagcaaaga tactacttaa tatgaatgtt aaaaatataa ttttatgtga tagaagtgga
    10501 gcattggaag ctagtataga aaatctaaac tatgttcaaa gagaaatgtt aaaagtaaca
    10561 aatataagaa atgaaaaagg acctttaaaa gatattataa aaggaaaaga tgtatttatt
    10621 ggcgtttcag gtccaggagc tgttacaaag gaaatggttg aaagtatgtc tgagaagcca
    10681 ataatattgg caatggcaaa tcctactcca gagataatgc cagaagaagc aaaattaggt
    10741 ggagcattta taatgggaac aggtcgttca gacttcccta atcaagtcaa taatgtactg
    10801 gcttttcctg gaatatttag aggtgcactt gatgttaagg ctaaagagat aaatgaagaa
    10861 atgaagatag ctgctgcata tgcaattgct aatacaataa gtgatgaaga aatatgccca
    10921 gagtatatat taccagatgt atttaataag aatgtagtaa aaaatgttgc taaggcagtt
    10981 aaagaagcag cgataaaaac caaagtaaat agaatataaa tttttatatg ttcatatatc
    11041 cttatcttat cgggtatatg ggcattttta ttataggttt atactcatat atccttactt
    11101 ttatatacat atctttatga ttaaaggtgt tagaaaatgt agtaaatttt atactatcag
    11161 actctatctt tattacttta gtagatacat ggtggtaaag gtttatagaa aaaaatatag
    11221 gaaggcagat ttttattgtt gcgtatatat gagaatgata taatatgaat attataaatt
    11281 aataaattta aatttatgga ggtacaagag atgatggaat ataaagttaa tgaccaagaa
    11341 cttaatgctt caatgtttat cccattcgtc aacaggatat ggccaggaga ttataatatg
    11401 gataaaacac agactgcatt atcaaaaact ttgaatataa ctgcttatga tgataaagtg
    11461 cttgtaggat gtctgcgagt tctttcagat ggttattatt ttggaacaat tacagaattg
    11521 cttgttcttc cagagtatca gaaacaaggc attggtagta agcttttcca gcttgctaaa
    11581 gagaacaccc caactatgct atattttggt gcacagccag gagtagaaga gttctatgaa
    11641 aaaaatgggt gccaaagaag tctgcaatcc tacataataa aaaagaaaga tagttattaa
    11701 agttccagct ttcaataatc ttaaaagtac aatattttag tggaatcatt tcatttttta
    11761 ttactaatat gacataaaca tgtcatatta gcattgatat acttttaata tggttaagag
    11821 ccaaagaaaa atataaggag tgatttaaaa tggaagaaac taaattttgc caatgctgtg
    11881 caatgccaat gggacaaact gatgaattat atgggacaaa taaagatgga agtaaaagta
    11941 ctgattattg tagttattgt tttaaagatg gtgagtttac agctgatata agtatggaag
    12001 agatgataga agtttgtatc cctcatatgc ttcaaagtaa taaggatatg actgaagatg
    12061 aagcaagaac aatgatgaac aatttctttc caacattaaa acgctggaaa taattttatg
    12121 caaaattagt tatatgcaaa acatgaaata tggtgttgag aataaggggt ggtgtgcttt
    12181 atagcatacc acctgttttg ttacttggag ttcagttatt ttcctaaata ttttaaatat
    12241 actattttag ataagttccc tcttcatctt gataaattaa tccttttttc ataagcactc
    12301 caagagctcg tttaaaattt ttcttacttg aattaaataa tatagaaata tctttagggt
    12361 cagatttatc attaaatctc atatatccat cagaaccttc taaataactt aaaatcttat
    12421 tttctaaagt atcaagttca tcctttctat ttcctctagg agaaagacca agttttccat
    12481 cttcatatat ttttatgaca tgtaaatttt caagaacatc accagttttt agttcagtaa
    12541 agtactcatt atgaagtatt acaccagcat atttattgtc tacacatatc attgcagaat
    12601 tattagtttg gaatccatat acaactccag ttacaatatc tcctacattg taagtatggt
    12661 ctgttaataa gtatgaatct atgtctgtag tagcagcaat tcttttgctt ttgtctaaat
    12721 atatataaaa taaatatttt tcgtctctaa atagtggata agtcttagct ttaaaaggaa
    12781 ctaatatgtc tttaggaagt cccatatcta taaaagtacc aatgtctgta ttatcaacta
    12841 cttttaaatg tgctacatcc ccaaccttag ctaaaggcgg tattaaagtt gcagcagttc
    12901 tgtcatcaga atctttaaat atgaaagcat ttacttcatc acctatgttt atttcatttt
    12961 ttccgattaa tctattatga agaagtatat cgtcttttgt gttattagtt tgtccatcca
    13021 aaaaatatcc aaattcagtt tttcttttta ctgtaagttt attaaaatca cctatgttta
    13081 tcaaattaaa atcatcctct cattttatat ttataattta gccataatat acttatgtag
    13141 tagtttgtca cagtatctat attagtatta gtgaaattta caataaataa tatagttatt
    13201 tatgtatttt tcaattctct agcttcttat atagtataaa ctccaatttc ttttttgtct
    13261 ttaggtttta ttaaaatttt tacaaaataa gttaaaaagt attgaaataa aatttctttt
    13321 aaagtataat tggtatatac caaaattggt atataccata tcgaaaagtg gtgactatat
    13381 gaaaatagta aataaatcta gtaatatacc attgcatact caattaagtt caataataag
    13441 agagatgata gaaactggtg agcttaaaga gggcgatgca ataatgccag aaagagaact
    13501 ttgtaacata caaaatgtaa gtcgtatgac agtaaataaa accattgttg gattagttac
    13561 agaaggactt ctttataggg tacaaggtaa agggacattc gttgcaaagc aaaaaaagaa
    13621 gtatcagttt tcaaatgtaa aaggttttac tgatgttatg aaagaaaagg gagtaaacat
    13681 aaaaacggat atattatcct ttgagatgga actaccagat gatttagtta aaagaaagct
    13741 tggaataagt gataatacta caaatatata taagattgtc agacttagat atactgatgg
    13801 agagccattt ggattagaaa tagtatatct atcagaagaa atgtgtaagg gtctaacaaa
    13861 agggatattg gataattctt cattatatag ggttttaaat gaaaaatatg gctataagat
    13921 acaaaaagct gaacaggtaa tggagccagt aatactttca gatgaagaaa gtaagcttct
    13981 tgaaacagat gaaggtgctt tagctcttaa acttcataga aattcctata atagagaagg
    14041 tagccctata gaatatacca tatcaatatt tagaacagat aaatatcaat atgaaatagt
    14101 attgagtgag taggtgaata atatgaaatg tttaattaat ggaaagataa tattaaaaaa
    14161 tcaaatctta gaaaataaag tattagtatt tgatgaaaaa ataattgata tagctgatag
    14221 tgtaccaaaa gattgtgaag ttatagatgc tgatggaaaa tatatatctc cagggcttat
    14281 tgatattcat atacatggaa acatgggaaa agatacaatg gattcgactg atgaatctat
    14341 tgaaacaatt tcaaaatcaa ttatgagaca tggagtaaca tcttttcttc caactacaat
    14401 gactatggat aaagaacatg tttatgatgc acttgaagtt attaaaaaag cccaaaatag
    14461 aaagcttgaa ggggcacaag tattaggagc acatttagaa ggacctttta taaatgagaa
    14521 ttataaggga gcacaaaatg aaaaatttat aataaattca aaatacgaat ttataaaaga
    14581 atataaagat gttataaaag ttataactta tgctccagaa aaagatattg attttgattt
    14641 tactagagaa ataaaaagat gtacagatat agttttatct attggtcata gtaatgcaaa
    14701 ttatgaccaa gctaaagaag ctataaattt aggagtaact aatgtaactc acatgttcaa
    14761 tgcaatgact ggtttaaacc atagagaccc aggcgttgtt ggtgcagcac ttacaactaa
    14821 tgtgtacagt gagttaatag cagatacaat ccatataaat aaagatttat ttcaatttat
    14881 actaaataat aaagggaaag aaagactgat tttaataaca gattctatag aagctggtgg
    14941 tcttgaagat ggcaattatt ctcttggagg tcagaaagtc atagttaagg gtaatgaagc
    15001 tagacttgaa aatggagcat tagctggaag tgtgttgtct ttaaataaaa tggtatttaa
    15061 cttcttagat aatacaaacc ttaaagtgaa tgaagcaatt aatttagctt ctttaaatcc
    15121 agcaacatct ttgggaataa atgacaaaaa aggaagctta gaaataggta aggatgcaga
    15181 tatagctgta tttgatgaga atttagattg taaaatgaca ctttgtttgg gggacgtagt
    15241 atataaaaat atatagtata caaaacaaac tttaaagaca gtaaaaacaa tataaaaaat
    15301 aataaattaa acttacatta gttaaagtag tagttaaaat ttaggaggaa taagatgaga
    15361 gtattagtgt gtaaagatta tgatggaatg agtaaaaaag ccgctgaaat gatagcagct
    15421 caaatagttt taaaaccaaa ttcaatactg ggactagcta caggaagtac accagtaggt
    15481 atgtatagag atttagtaaa aaaatacaat gataatatag tagatttttc agatgtgatg
    15541 agctttaatt tagatgaata ttataagtta ccaatatcta atgaccaaag ctatgattat
    15601 tttatgaaag agaatctatt taatcatgta aacataaagc cagaaaatac tcatctacca
    15661 aatggaatgg ctgatgatat tgaaaaagag tgtatgaact atgaagcttc tatagatgca
    15721 gctggtggta tagatgtaca agtacttgga ataggtcgta atgctcatat aggttttaat
    15781 gaacctgata ctaaatttgc aaaaagaact catgtagttg aacttacaga gtctacaata
    15841 gaagctaatg caagattctt taaatcaaga gaagatgttc ctaaaaaagc tgtaagtatg
    15901 ggaataggtt caatattgaa gtctaagaaa atattgcttt tagcttcagg agaagaaaaa
    15961 gctgatgcag tatataatac tgtttacgga gatataactc cagaagttcc tggttctata
    16021 cttcaacttc ataaagacac tatagttata gtagatgaag cagcagcaag taaactgaat
    16081 ccaaaagatt ataaattagt ataagaatag aatgtagttt aagtaaaaaa tagctatcat
    16141 tgagtaatca aatttattta atgatagcta tttttattta aattttttac ttctttttat
    16201 ttaaattagt tattattgtt taaattactt gcttattact ttttacgaaa actcgttatc
    16261 aagaagtatc caaataaaat gttaaaaatt attatgttta gtgggattct atcaagcata
    16321 ataaaattac ctataattgg gatattacca actggaaaca taaagaagaa tacaggcatc
    16381 agtgatagta aaaaagatgg aaaacaaaga agaagtaatc ttggaatatc aatataccaa
    16441 ctaccatcct ttttgtattc tctaatcaat aattcagttc ctagtaataa accaatacca
    16501 ccagaggaaa ttaaattaat aaaaatgtat cttttaaagt cttgcatata accagtgtga
    16561 aattgagtat agaaatcata atttaattta acggctaaaa aatacataag caatagaatg
    16621 attaaaaata aaagatatct aagagctttt ttcattttaa attctccctt cagaaatact
    16681 ttattcagtt ttattttgtt ggaatctgat tttatcattt agtttaagaa atccataata
    16741 ttagtgaaga atgaaataag tattatatat gaataaatat ttttagaatt aaggtgaact
    16801 gtagtgctta atataactat aatattaatt gtttgaatat tcaataaaaa gtttgaaaaa
    16861 tatcaatttt gatataaact gaataaatac agttgaatat taaattatta ttttatcaaa
    16921 aatatgcaaa gtactacacc ttcaaatatc acctaaagta attaaaaggc aattaaagtg
    16981 aagtagttca agtatttcta aaataagttt aataaattct ataataattt attttttgcc
    17041 ttaaaattgc cttaaaatcc aaacaatttt aaaactaatg tactataaaa agctggtata
    17101 atttaaatat agtaaaaaat aagatttatc ttatctattg ggatttaatt atttaatcaa
    17161 tatatttata ccatttaatt taaataaaaa gtctattaag gagtgagctt atgagtaagt
    17221 taatttatat agcagatgat gaagataata taagaaattt ggtaaagaca ttcttaaaaa
    17281 atgaaggtca tgatgttatg gattttaaaa cgggtgatga acttttagaa caatttaata
    17341 taaaggagtg tgacttagta atactagata taatgatgcc tggctcaagt ggttttgaag
    17401 tatgtacaaa acttcgtgag aaaagtacag tcccaataat catgcttact gcaagagata
    17461 cagatataga ttatattaca gggataacct taggtagtga tgattatttt acaaaaccat
    17521 ttagcccaat gtctttggtt atgagagtaa aatctatatt tagaaggata gagtttgaaa
    17581 agaaacaaaa ttatgataaa tatagtaact cgatagatat ggaattaaaa tttggtgatg
    17641 taataataaa taaaaagaat aaaatcgtta caagtaaaaa tgtaaatata gaccttacac
    17701 caaatgaata taacctattg acttatttgt ttgaaaatat agatagagca gtttccagag
    17761 atgaattatt aaacaaaata tggggatacg atatagaagt tgagacaagg gctgctgatg
    17821 atacagtgaa gagattacgt aaaaaaattt taaatacaaa tattttaata gaaactgtat
    17881 gggggtttgg atttaggttg aaggagaaaa gttaagatga agaatggaaa tgacaagaat
    17941 agaattggaa agattaaatc caaatttaaa ttaaagttct caaagaaaaa tataagcata
    18001 aaaactagga ttttgttgag tatactttgt ttgataatta tagtatttat gataatatta
    18061 gtatctttta atgtatttct tgatacatat ataaaaacaa ctgcgaatga agaattgaca
    18121 aagtctacag aaatagtaga acatatggat agtaatttta gacctattaa gccaccacaa
    18181 gatgatggaa agcttcctcc caaagtatta tctaatttta tgagaaatgt acaagataaa
    18241 gttaggatgg cagaaacaca atcagatgct gatgctatgg tagttgattc taagtataac
    18301 ctgatatttc caacaagaga ggatgatttc ttaaaaaatg ttgatgagat ggagctgatt
    18361 agggagtgta ttcaaaatga aaaattagat ttaaattcag atgaaaatac acggatatct
    18421 accagaaata aggattatta tatttcaact gtaaaaatta ctagtatata tggtgaacaa
//
LOCUS       DAFAZV010000065        18463 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFAZV010000065 DAFAZV010000000
VERSION     DAFAZV010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18463
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.065"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(514..1386)
                     /locus_tag="KOU88_003482"
     CDS             complement(514..1386)
                     /locus_tag="KOU88_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3213315.1"
                     /translation="MEETNEMKDSKHLISNIQSQYTRLSKGQKLIAQYILNNYDKVAF
                     MTACKLGETVGVSESTVVRFANALGYSGYPKLQAALQELIKNKLTTVQRVEMAHDYSD
                     DFAILNKVLKSDIDNIRSTLEEIDERAFKEASNKLLRARKIYILGMRSSFVVAQYLGF
                     YLDIILDNVHIIRMDMGDAFEQIVRINEEDVIVAISFPRYSKKSYQIVNYAKEKGAHV
                     ISLTDSLFAPVASLADNTLLVKSNMASFVDSLVPALSISNALAISVGMKEKEDIKQHF
                     DDLEQIWKRYSVYE"
     gene            complement(1780..2358)
                     /locus_tag="KOU88_003483"
     CDS             complement(1780..2358)
                     /locus_tag="KOU88_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK3213316.1"
                     /translation="MAYAKYLTKITDINKFYLENIINEGDIVIDATMGNGYDTRYLAE
                     KVGEKGFVYAFDIQEEAIKSTRKKLEKEGYTDRVKLIFDGHEKMNQYIKEEVSCVLFN
                     LGYLPRAKHSIITKPDTTLKAIKLSLEMLKENGVISIAIYTGHDGGQEEKDCIYNLVN
                     NLNQDEFNVLESKFLNQVNNPPQLILIEKKKA"
     gene            complement(2416..3132)
                     /locus_tag="KOU88_003484"
     CDS             complement(2416..3132)
                     /locus_tag="KOU88_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBK3213317.1"
                     /translation="MRINKYIASCGIASRRKAEEIILGGRIKVNGSVVKELSFNIDEE
                     KDIVEFDNKKVKPSENYIYIVLNKPEGYITTVKDQFNRPSVIDILKDVRERVYPIGRL
                     DYETSGLLILTNDGDLTYKLTHPKHEIDKTYVASVKGIISDDEIRQFETGLKIEDYTT
                     APAKIRVTKENKEKNYSVCEITIHEGRNRQVRKMCKAINHPVLNLRRISVGKIVLKDT
                     KVGEYRYLTEDEIKYLKSIK"
     gene            3323..4408
                     /locus_tag="KOU88_003485"
     CDS             3323..4408
                     /locus_tag="KOU88_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK3213318.1"
                     /translation="MIIISRENIKYYLIVVFIGILFFKFINTPSDFISSIEGFLKFFS
                     PFLLAILLALLLNPLVMLFEVKFKAHRLLAIFLSYIFIGFILAFAIRLLIPSIANTLN
                     RLINEMPMYTDYIDSFIEKNMSNIDFLKTLIPHIQHSLDNLLKEASNFVGKIPKNFLI
                     YTLSISSMLFNMTMGFILSIYIIYDKEKIALGFKRFLYSSTARNKADNIIEFFRTTHD
                     IFYDYLLGRILDSLIIGIIAFLGFQFVIRIENALFLASIIFLGNIIPYFGPFIGAIPP
                     IAMTILYSPQKTIWVIAFLFILQQLDGNFIEPKVMGNQVGIGAIWVISAILVGQSLFG
                     FIGVFLSVPIAAVVKTYVDKYIDNRLQ"
     gene            complement(4563..5222)
                     /locus_tag="KOU88_003486"
     CDS             complement(4563..5222)
                     /locus_tag="KOU88_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK3213319.1"
                     /translation="MRGRVILLISILSIFLVGCSFNKKDEINLVEQGKTYLEKHNYKK
                     AMESLSSALEEDSTNENARAMYMQAMRMSNMTEFEELKNYEGAIKELKLIEKIKNGSS
                     VIKEEATKKKEELTKLEKEQNEAEEQRKKKAKDTAGEDRYRVESDARKSSYSGSSKNN
                     KSSSKNNDKKSDSNKSDNNNSSSQNQEKPNNSNPTPAPTPQDTTGGSDSGGNSQNSNN
                     Q"
     gene            complement(5439..6731)
                     /gene="lysA"
                     /locus_tag="KOU88_003487"
     CDS             complement(5439..6731)
                     /gene="lysA"
                     /locus_tag="KOU88_003487"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBK3213320.1"
                     /translation="MKLHGTMTVNNDELYIGGVSCLELSKKYQTPLYVFDEALVRQNC
                     REYIEYFKAREGKNKVAYAGKAFLPLYMCNLINEEQMCLDVVSGGELYTAYKSNFPME
                     KVFFHGNNKTKEEINMGLDLGVGKFVVDNFYELDLLEALCEDKGKTQEIYFRITPGIE
                     AHTHDYIKTGQIDSKFGFALVNGDLFRAIEKLSEYKNIKLVGLHAHIGSQIFDVEPYI
                     DTVDIMMNLVKEIKEKFNIQLTEIDLGGGVGVYYSEGDKPKTIKEFCETIITKAETSC
                     KELGIEVPTLVIEPGRSIVANAGSTLYTVGSIKDIKDVRVYVSVDGGMTDNVRPSLYQ
                     ASYECSIVNKINHEAMNHVTIAGKCCESGDILIGDINIMDIKSGDILITTSTGAYGYS
                     MSSNYNKIPRAAVVSVFDGNDKIICKRQSYEDLLALEI"
     gene            complement(6749..7942)
                     /locus_tag="KOU88_003488"
     CDS             complement(6749..7942)
                     /locus_tag="KOU88_003488"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBK3213321.1"
                     /translation="MSIIVQKYGGSSVADTEKIKSIAENIIERRKENPQMVIVVSAMG
                     KSTDEYITLAKELSNEPSKRELDALMSTGEMISASLLSIALNALGCKAISYNAYQLNI
                     KTSGLHGKSQIDDINVNRIKNSLDEGNVVIVTGFQGINEDGDVTTLGRGGSDTSAVAL
                     AVKLNGKCEIYTDVDGIYFTDPRKYSKASKLDEIEYEEMLELASLGAQVMHSRSIELA
                     QKYGVEIYVGRTCGTEKGTYIRGGKDMKLEDKVITGLATSDDDSSITIKDFKAENISS
                     LFEDIATIGISVDMISQTAPILDKISVSFTVPKEELGECKKIVSKYTDEEHVVIDNNI
                     TKFSLVGLGMKNTSGVAAKVFKIFNENGIMIKLITTSEIRITCAINSDDKQVAIEKIA
                     EVFNI"
     gene            complement(8303..8920)
                     /locus_tag="KOU88_003489"
     CDS             complement(8303..8920)
                     /locus_tag="KOU88_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213322.1"
                     /translation="MTNMEKEILLLISRVRCVTESQFRKIYGDQKRYNKKNFKKTLRK
                     MCSEYTLKKYPCDVDYYNYKDLSYVYYLNGSKLFKGDDLIKALVGSELVVRINTAGCD
                     VKRFYRNVSVDDVKYDLFIEYTDQFGNIKQVLVDVDLNNEIDISKYENLSKKIDKSTI
                     PFFKVPNVLVVTPDNLSELNDLERYDNEYSINFIDLGLNKLFNCI"
     gene            complement(9090..10790)
                     /locus_tag="KOU88_003490"
     CDS             complement(9090..10790)
                     /locus_tag="KOU88_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213323.1"
                     /translation="MKRYLKTYGVALIIVIIYSFIKLPVLRLDFTSLFSVGIIFFVVA
                     GILDMMLDRNERASKMAKYNFSIAIALLVYIVVVPFITSTPVLHAKSYRELLGKVTES
                     KFTDDISPVSVNDIRLVDEDMAMKLGDKKLGEVPAIGSVSKLGKFHIQNVDGELYWVA
                     PLVHRDIIKWITSLSGTSGYVKVSASNPQDVQLVQEIDGKPIKIVYQPEAYLHQDLQR
                     HLYIHGIVNVGMTDFTLEINDEGRPYWVVSLYEHKIGYGGANATGIATVDAETGKINV
                     YDVKNTPKWVDRIQPQSFVTDQIKDWGVYVNGFLNSVISEKGVLVPTEGTSLVYGNDN
                     RSYWYTGITSSGGDESTIGFMLVDSRTKEARLYKQPGATETAAMKSAEGNVQEKNYEA
                     TFPVMYNILGQPTYVSSLKDKAGLVKRVAFVSVEDYNVLGIGEDKNEALRNYKDALES
                     KGNDLKLDNDLKDEVLEGTVTRISPDVRGGNTNYYVTLDSNKDIIFRATSKVSSELPL
                     TQVGDKVKISYSKEESGVIEMSEFDNLNIANFEDKKAKEKTGTDENTDSKDSENQGNV
                     "
     gene            complement(11187..11750)
                     /locus_tag="KOU88_003491"
     CDS             complement(11187..11750)
                     /locus_tag="KOU88_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213324.1"
                     /translation="MNKVYIVTTYTGTILSYLIRNISKKLYTHVSISLNENLKPMYSF
                     GRLNPRNPFIGGFVEENINQGLYAIRKNTVCRVYSLEVDNLQYENLYKNIKLISDYRE
                     DYYYDTMALIYLLMNIQRQSEYKYVCSNFVADMLEKSEIDILNKQAFEVTPNDFYNLS
                     GLTLEYEGLLSEYNSRQHSYVSKIANI"
     gene            complement(11909..12622)
                     /locus_tag="KOU88_003492"
     CDS             complement(11909..12622)
                     /locus_tag="KOU88_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2140 domain-containing protein"
                     /protein_id="HBK3213325.1"
                     /translation="MGKVAKILLSLIVIVLVLTGIVVYILTPKERYDVSSQNNKIIDE
                     EYLSKGSYINSMEVVKNPLRMVGKISVSEEEFKNLIYTLMQKHGINELENNFVEMKNG
                     KIKVAGPYKVFGLVNSQYELELRPTLKDGNLVVSLENVKIGKFKLSDKMLEKILSNYN
                     KKVPFEVNGNKITLEKSYLYPITLKNISIKKGNVDLDMEVEIDLKSQINGALGYLKDS
                     GKVQDILNHLINLKKTSVG"
     gene            12914..14578
                     /locus_tag="KOU88_003493"
     CDS             12914..14578
                     /locus_tag="KOU88_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase/YqeY domain fusion
                     protein"
                     /protein_id="HBK3213326.1"
                     /translation="MSNETNSSNFIKNIIINDLETGKHDSIITRFPPEPNGYLHIGHA
                     KSICLNFGLAKEFNGKANLRFDDTNPLKEDVEYVESIKEDVKWLGFDWNELNFASNYF
                     DEMYKRALILIKKGKAYVCDLTQEEMREYRGTLTEPGKESPHRNRTIEENLDLFERMK
                     NGEFKDGEKTLRAKIDMSSPNINLRDPIIYRISHSTHHNTGDKWCIYPMYAFAHPIED
                     AIEGITHSICTLEFEDQRPLYDWFVKECEMENIPRQIEFARLNINNTVMSKRKLKQLV
                     DEGIVDGWDDPRVPTISGIRRKGYTAEALRNFCSEIGVSKVNSTVDSQMLDYFLRENL
                     QPKAPLTMGVLRPLKLIITNYPEDKIEMLEIENNAKDESQGKRLVPFSRELYIEQDDF
                     MEEPVKKYFRFFPGNEVRLKGAYFVKCTDVIKDENGNVVEIHGTYDPETKSGSGFTGR
                     KVKSTIHWVDAKSAIPCEFRLFEPLILDDIPENEGKHFLEQINPNSLEILQGFVEPTQ
                     IKDAKPFDKFQFVRNGFFSIDNKYTTDEKFVFNRIVPLKSSFKPGK"
     gene            complement(14685..15584)
                     /locus_tag="KOU88_003494"
     CDS             complement(14685..15584)
                     /locus_tag="KOU88_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBK3213327.1"
                     /translation="MKKVKLIYNPNSGEKKILSNLDTIIELYQEKNYLLIPYRLTIKE
                     PVKNAFKEVDSSYEHILIAGGDGTVDLVVNAMKELDIKIPIGILPTGTANDFSNALQI
                     SFDIKEAINEIINSKPKKIDIGKVNNKYFINVASAGMFTDVSQRINTDLKNSFGRISY
                     YIKGIEEALYMRKFKIKVSSEEMYYDGDMYLMLIFNGKTAGNINLAYKAEIDDGYLDV
                     IIFKGMPIPKSIPVLISVLRGDYLDQYNGNEILYFKTKKVHIECEDSLITDIDGEKGP
                     DFPLNIECIKDGIEVMGICSEKS"
     gene            complement(15611..16249)
                     /locus_tag="KOU88_003495"
     CDS             complement(15611..16249)
                     /locus_tag="KOU88_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003356606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein"
                     /protein_id="HBK3213328.1"
                     /translation="MDQNLNWLNEKRIEKTIKSLENNNMKGYLVSNKEELLKKIEEIV
                     KAGSLVGCGGSMTLFETGVIDFIREKYNFLDRYAKDIKPEEMKEIYRKSFSADAYFTS
                     TNAITEDGELYNLDGNGNRVAAMIYGPDKVIVIAGVNKIVKDVDEAIKRTKTIAAPAN
                     CKRLSTNTGCKTTGICIDCSSPGRICCSYTLIKRQLTPERIHVIFLNEDFGY"
     gene            complement(16586..17584)
                     /locus_tag="KOU88_003496"
     CDS             complement(16586..17584)
                     /locus_tag="KOU88_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4003 domain-containing protein"
                     /protein_id="HBK3213329.1"
                     /translation="MEQSFINGKVNLLIENYKALNEVKGSWQMGLIQHSCALAFTLKN
                     KRISPRLVEERIELIKKNTGLFSNFRGYNMFYMATLLSFESNPESSFKMILDIYKELK
                     SEKFWGDTYLPLTASIVYENREKMDYLTCISKMKIIYDYMRKKHPFITSSDDYCNIAL
                     IAIHSKNLDEDLEYIEKCYEFLNENGFYKGNDLQALSQILLFSDDRTMLKCKKTIELK
                     KAFKENDCKMNYYGYPIIGAISLLDYREDEIIEEIKNVSNKLKEEKGFGNWSLGKSNR
                     VMISSAIVASIYADLIRNENNIGSITNNIFLNIVVAIQIACVMAATSAAIASSSSN"
     gene            complement(17682..18257)
                     /locus_tag="KOU88_003497"
     CDS             complement(17682..18257)
                     /locus_tag="KOU88_003497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213330.1"
                     /translation="MKLKEALITCVVCSVCLTPLLVNGETKIDADHCKESIVNIDTIV
                     KSGKSFNSKYNQGMEDYKNSDEYKLKVQKEKLQNQLGIKIKKLVPITFEVSYYTSLNQ
                     ENGYGAITATGDDLEDGFVANNHLSFGTKIIVDGKLKTVMDRGSSKYFSNSNAIDVFV
                     PKWSNESESEYYDRVNNMGRHYKKGYIIVEE"
BASE COUNT         5974 a         3058 c         1954 g         7477 t
ORIGIN      
        1 tcttaatatt tataaaaact ttattttatt tttataaagt attatatttc taaaaaagtt
       61 tccctttccc caaaaatggc tacttaaaaa atcaagattt catacctaac tactaattct
      121 atgattttta aatttttcaa cttctttgtc aaagttaaaa taaaatacta aaagacacat
      181 attatagtga acaaaaaaga tagaaataca tattttaata taattttaat aagatattat
      241 atacttaaat acaaataaaa ttaattttat aattgttaat taaggaaatg atattgttta
      301 gagaaataaa aaaagcactc tccatgaatg gaaatgcttt ctttaataaa ttagttgacg
      361 tagtaaagat gtattcagaa tacatcttta tgttttgagt ctcgaaatat ttatttgtat
      421 tatttaaacg aaaatttatt ttttaagtga taatcgagta tttactaata aggctatgat
      481 tctcaatttc atagccttat taatatacaa actttactca tacacagaat atcttttcca
      541 aatttgctct aaatcatcaa aatgctgttt aatatcttct ttttccttca tcccaacaga
      601 tatagcaagg gcatttgaaa tactaagagc tggaactaga gaatctacaa atgaagccat
      661 attactctta actagaagag tgttatctgc aagtgatgct actggcgcaa ataagctatc
      721 tgttaatgat attacatggg ctcctttttc cttagcataa ttgacaattt gataagattt
      781 cttagaataa cgagggaaac taatagcaac tattacatct tcttcattta ttcttacaat
      841 ctgctcaaaa gcatctccca tatccattct aattatatga acattgtcaa gtattatatc
      901 taagtaaaaa cctaaatatt gagctactac aaaagaactc ctcattccaa gtatatatat
      961 ttttctcgct cttaaaagtt tgttagaagc ttctttaaac gctctctcgt caatttcttc
     1021 tagtgtagac cttatattat ctatatcact ttttaaaact ttgtttagta ttgcaaaatc
     1081 atcggaataa tcatgtgcca tttcaactct ttgtactgta gttagtttat tttttatgag
     1141 ttcttgaagt gcagcttgta atttaggata tccactataa cctaatgcat ttgcaaatct
     1201 tacaactgta gactcactta ctcctacagt ttcacccaat ttacatgcag tcataaatgc
     1261 aactttatca taattattta aaatgtattg tgctataagt ttttgaccct tactcaatct
     1321 cgtatattga gattgtatat ttgatatcaa atgtttactg tccttcattt catttgtttc
     1381 ttccattttt ttctcctttt agttatataa actattttgt tttattaaca ctgtcttttt
     1441 ctctaaaaat tttatttttt atctcaattt catcttagtt tttatcatag cttcttaaac
     1501 tcataaaatt ctaacttttc tgtaccttat acttcacata gtattttcga ttaaatttat
     1561 tataccatct ttccttgcat tttttaatat ttatccaata tttcttttaa atttttcaat
     1621 ttttactcat ttaaaagtta tctatcttat tttgcatatt tagatgtata ttttgttttg
     1681 agaataagct gttgtatact tattatttaa agtattttta ataggtcaca ctatatatat
     1741 taactcttaa tacaatcttg tcaagttttt tagtatttat tatgcttttt tcttttcaat
     1801 taaaatcaat tgtggtgggt tattgacttg atttaaaaac ttagattcta aaacattaaa
     1861 ttcatcttga tttaaattat tgacaaggtt atatatgcaa tctttttctt cttgacctcc
     1921 atcatgccct gtatatatgg caatgcttat tactccattt tcttttagca tttctaaact
     1981 taactttata gcctttaaag ttgtatctgg tttggttata attgaatgtt tcgctcttgg
     2041 aagataaccc aaattaaata aaacacatga aacttcttct tttatatatt gattcatttt
     2101 ttcatgccca tcaaatatca attttactct atctgtatat ccttctttct ctagtttctt
     2161 tcttgtagac tttattgctt cttcttgtat atcaaaagca tatacaaagc ccttttctcc
     2221 aaccttctca gctagatacc ttgtatcata cccatttccc atagtagcat caattactat
     2281 gtcaccttca tttataatat tttctaaata aaatttattt atatctgtaa ttttagttaa
     2341 atactttgca tatgccataa tactatttct ccctactatt aactttattt cattttttct
     2401 caatttattt ttatcttatt ttattgattt taaatatttt atttcatctt ctgttaggta
     2461 tctatattct ccaactttgg tgtcttttaa tactattttc cccacagaaa tccttcttaa
     2521 atttaaaact ggatgattta tagctttgca catttttctt acttgtctat ttctaccctc
     2581 atgtatagtt atttcacaca ctgaataatt tttttcttta ttttctttag ttacccttat
     2641 tttggcaggt gccgttgtgt aatcttctat ttttagtcct gtttcgaatt gtcttatctc
     2701 atcatcactt ataattccct tcacacttgc cacatacgtt ttatcaattt catgctttgg
     2761 atgggtaagc ttatatgtta aatcgccatc attagtaagt attaataatc cactagtttc
     2821 ataatctaat ctccctattg gatatactct ttcccttaca tctttaagta tgtctattac
     2881 actgggtcta ttgaattggt cttttactgt agttatatat ccctctggtt tatttaatac
     2941 tatatatata taattttcgc ttggttttac ttttttatta tcaaattcta ctatgtcttt
     3001 ttcttcatca atattaaaag ataactcttt tactacactt ccatttacct ttattcttcc
     3061 tccaagaatt atttcttctg cttttcttct tgatgctatt ccacaagaag ctatatactt
     3121 attaattctc atacttaatc cttccttatc ttaaattatg tgtgtttaat atttttatca
     3181 atgttaattt tgctacatta ttatactata ctagacctta attaaaaaca agcaaaaaaa
     3241 ttatttaatt ttcctaaata attgtaattt cttttcacat actattaata tgtaatagct
     3301 gactaaacac tattttaagg aagtgattat tatttcaagg gaaaatataa aatactattt
     3361 aatagtcgtg tttattggaa ttttattttt taaatttatt aatactccat cagactttat
     3421 atctagtatt gaaggattct taaagttttt tagcccattt ttattagcta ttttacttgc
     3481 tttactttta aatccacttg tgatgctttt tgaggtaaaa ttcaaagcac atagactttt
     3541 agccattttt ttatcttata tatttatagg ttttatttta gcctttgcca ttaggttatt
     3601 aattccatca atagctaata cattaaatag attgataaat gaaatgccta tgtatactga
     3661 ttatatagat agttttatag aaaaaaatat gtcaaacata gattttctaa aaactttaat
     3721 tcctcatata caacatagtt tagataattt attaaaagaa gcaagtaatt ttgttggtaa
     3781 aattcctaaa aacttcttaa tctatacact tagtatatct tctatgctat ttaatatgac
     3841 aatgggattt atactatcta tatacattat atatgacaaa gaaaaaattg cattgggatt
     3901 taagagattt ctatattctt ctactgctag aaacaaggca gataacatta tagaattttt
     3961 taggactact catgatattt tctatgatta tttacttggt agaatattag actctcttat
     4021 tattggtata attgcatttt taggatttca atttgttatc agaatagaaa atgctttatt
     4081 tttagcttca ataatattct taggtaatat aattccctat tttggtcctt ttattggtgc
     4141 aatccctcca atagccatga ctatattata tagtccacaa aaaactatat gggttattgc
     4201 atttctattt atattgcaac aattagatgg aaattttata gaaccaaaag ttatgggtaa
     4261 tcaagttggt ataggagcta tatgggtaat atctgctatt ttggtgggac aatctctatt
     4321 tggtttcata ggagtttttc tttcagtacc aatagctgct gttgtaaaaa cttatgttga
     4381 taaatatata gataatcgtt tacaatagct tatctctact gtgactttaa tttttagttt
     4441 aaaatttaac tgctatttat taaattattt ctcaaaaaat atctcttagt aagaaaaaat
     4501 tgctaagaga tattttttat aatatataat ttgttcatta aatttatgca tatattttat
     4561 acttattgat tatttgagtt ttgagaattt ccaccactat ctgaaccacc agtagtatct
     4621 tgtggagttg gtgctggtgt tggattacta ttatttggct tttcttgatt ttgagaagaa
     4681 ctgttattat tgtcagactt attactatct gattttttat cattattttt agaactagat
     4741 ttattatttt tactacttcc actataagaa gatttccttg catctgattc aactctatac
     4801 ctatcttctc cagccgtatc ttttgccttt ttctttcttt gttcctctgc ttcgttttgt
     4861 tctttttcta atttagttaa ctcttctttc tttttagttg cctcttcttt aataacagag
     4921 gaaccatttt tgattttctc tataagttta agttccttga ttgcaccctc ataatttttt
     4981 aattcttcaa actccgtcat atttgacatt ctcatagctt gcatatacat agctcttgca
     5041 ttctcattag tactatcttc ttccagtgca gaggataatg attccatagc ttttttatag
     5101 ttatgttttt ctaaatatgt ttttccttgc tctactaaat ttatttcatc ttttttatta
     5161 aatgaacatc ctacaagaaa tatagataat atcgatatta ataaaattac tcttcctctc
     5221 attaaatccc tccttgtcat atactttaaa ttttatcata attataaagt ttttaaaata
     5281 ttttatattt attacaagaa atttgttagt aaaacaaaaa ataagcagat atgctacgaa
     5341 cgatacaata aaccaaaaat taatttagag atacatatcc tagcaaatct gctcataata
     5401 aactttaata tttaattttt attatatact tctctatttt atatctctaa agctaataag
     5461 tcctcatagc tttgtctctt acaaattatc ttatcatttc catcaaatac tgataccact
     5521 gctgctcttg gtattttatt ataatttgaa gacattgaat atccatatgc accagttgat
     5581 gttgttataa gtatatctcc acttttaata tccattatgt ttatatctcc aattaatata
     5641 tctccactct cacaacattt tccagctatt gttacatgat tcatagcctc atgattaatt
     5701 ttattcacaa tactacactc ataactagct tggtacaacg aaggtcttac attatctgtc
     5761 atacctccat ctacacttac ataaacccta acatctttta tatcttttat agaacctact
     5821 gtatacaatg tacttcctgc atttgcaact attgatcttc ctggttctat taccaatgta
     5881 ggtacttcta ttccaagctc tttacatgaa gtttctgctt tagtgattat ggtttcacaa
     5941 aactctttta tagttttagg tttatctcct tcgctataat aaacgccaac tcctccacct
     6001 aggtcaattt ctgttagttg tatgttgaat ttttctttta tttcttttac caagttcatc
     6061 attatatcca ctgtatctat gtatggttct acatcaaata tttgtgaacc tatatgagcg
     6121 tgaagaccta caagtttaat atttttatat tcacttaatt tttctattgc tctaaataaa
     6181 tctccattta ctaaagcaaa tccaaattta gaatctatct gtccagtttt tatataatca
     6241 tgtgtatgag cttctatacc aggagttatt ctaaagtata tctcttgagt tttaccttta
     6301 tcttcacata atgcttcaag caaatctaat tcataaaaat tatccactac aaatttacct
     6361 acacctaaat ctaatcccat gtttatttct tctttagtct tattgtttcc atgaaagaaa
     6421 actttttcca taggaaaatt tgatttataa gctgtatata actcgcctcc tgaaactaca
     6481 tctaaacaca tttgttcttc atttataaga ttacacatgt aaagaggtaa aaaagctttc
     6541 cctgcataag caaccttatt ttttccctct ctagccttaa aatattctat atattctcta
     6601 caattttgtc taactaaagc ttcatcaaat acataaagtg gagtttgata ttttttacta
     6661 agttctaaac aactcactcc tccaatatat aattcatcat tatttacagt catagttcca
     6721 tgaagtttca taatagcctc cccaaatttt atatattaaa tacttctgct attttttcta
     6781 tagctacttg cttatcatca gaatttatag cacaagttat acgaatctct gatgtagtta
     6841 taagttttat cattatacca ttttcattga atatcttaaa tactttagca gcaactccag
     6901 aagtattttt cataccaaga cctactaaag aaaatttagt gatattatta tcaatcacta
     6961 catgttcttc atctgtatat ttagatacta tctttttaca ttctcccaac tcttcttttg
     7021 gaactgtaaa tgatacactt atcttatcta aaataggtgc agtttggctt atcatatcta
     7081 cacttatacc tatagttgct atatcttcaa ataagctaga tatattttca gctttaaaat
     7141 cttttattgt tatagaactg tcatcatcac tagtagctaa tcctgttatt actttatcct
     7201 ctaatttcat gtcttttccc cctcttatat atgttccttt ttctgtacca catgtacgtc
     7261 cgacatagat ttcaacacca tatttttgtg caagctctat acttcttgaa tgcattactt
     7321 gtgctcctaa actcgctaac tcaagcattt cttcatattc aatctcatca agtttactag
     7381 cctttgaata ttttcttggg tctgtaaaat aaattccatc aacatctgta tatatctcac
     7441 attttccatt taatttaacc gcaagagcta cagcagatgt atctgaacca cctcttccaa
     7501 gagtggttac atcaccatct tcgttgattc cctgaaatcc agttactatc acgacatttc
     7561 cttcatctaa actattttta attctgttta cgtttatatc atcaatttga gactttccat
     7621 gaagaccact cgtttttata tttaactgat aagcattata acttatagct ttacatccaa
     7681 gtgcatttaa tgctattgat aataaagatg ctgaaatcat ttcaccagta gacattaaag
     7741 catctaattc cctcttacta ggttcattac tcaattcctt tgctaaagtt atatattcat
     7801 cagtggattt tcccatggca gacacaacta ttaccatttg tggattttct tttcttcgtt
     7861 ctattatatt ttctgctatt gattttattt tttcagtatc tgctactgaa cttccaccat
     7921 atttttgaac aattatactc atgctttctc cccctcaagc taaattttga taaataaaaa
     7981 cgcccaaagg tatactttgg acgtgtaaat ttcatagacc aagtaacctt gtagctcacc
     8041 actttaaaag tgacagcctt atgcatattc tgcataagtc cagaaaattt gtccgtcaac
     8101 aaaatttctt cggctatata ccctttcatc aattatcaac gcttaccagc tcctattgaa
     8161 tactattgaa tacagctacc tctaccctag gctcattatt tttaattaat ttattaatat
     8221 agttttatca tattctatat aatattgcaa caattatttt acaaaatgtg gcaaatcgat
     8281 agttttcttt tctaaagtta gcttatatac aattaaatag tttatttaat cctaaatcta
     8341 taaaatttat gctatactca ttatcatatc tctctaaatc atttaattcg gatagattat
     8401 ctggtgtaac taccaaaacg tttggtactt taaaaaatgg aattgtagat ttatctattt
     8461 ttttagaaag attttcgtat ttagaaatgt ctatttcatt atttaagtca acatcaacta
     8521 aaacttgctt tatattacca aattggtctg tatattcaat aaataaatcg tatttcacat
     8581 catctacact aacatttcgg taaaatcttt ttacatcaca acctgcagta ttgattctaa
     8641 caactaattc tgatcctact agagccttta ttaaatcatc tcccttaaaa agtttactac
     8701 cgtttaaata gtatacataa gagaggtctt tataattata ataatccaca tcacaaggat
     8761 atttttttag tgtatattca ctacacattt ttctcaaagt ttttttaaaa ttttttttat
     8821 tgtatctttt ttggtctcca taaatttttc taaattgaga ctctgtaaca catctaaccc
     8881 tgctaattaa aagtaatatc tctttttcca tattcgtcat agtacattct ccttgaagta
     8941 ttatttgcaa agttgtacta atattatatt aattttatga cattaaattt acaaagaatt
     9001 aaaataaaat agctaatttt tatagaatta aattctataa aaattagcta tcactatgtt
     9061 aagtactatt atcaatcttt ttatttaaat tatacattac cttgattttc agaatctttg
     9121 gaatctgtat tttcatcagt tcctgttttt tcttttgctt ttttatcttc aaagtttgca
     9181 atatttaggt tatcaaattc tgacatttct attacaccag attcttcttt tgaatacgat
     9241 attttgactt tatcaccaac ctgagtcaat ggcaattcgc tagatacttt tgaagtagcc
     9301 ctaaatatta tatctttatt tgaatctaaa gttacataat aattagtgtt accacctcgc
     9361 acatctgggc ttattcttgt cactgtgcct tctaatacct catcttttaa atcattatca
     9421 agttttaaat cattaccctt agattctaat gcatccttat agtttcttaa tgcttcattc
     9481 ttatcttcac ctattccaag tacattataa tcttcaacag atacaaatgc aactctctta
     9541 acaagaccag ccttatcttt taatgatgat acatatgttg gctgacccaa tatattatac
     9601 attacaggga acgtagcttc ataatttttt tcttgaacat taccttcagc tgatttcatt
     9661 gcagccgttt cagtagctcc tggttgttta tataatctag cttcttttgt tctagaatca
     9721 actaacataa atccaattgt agattcatct ccacctgaag atgttatacc tgtataccaa
     9781 taagacctgt tatcattgcc ataaactaat gatgtacctt ctgttggtac taaaactccc
     9841 ttttctgata taacagagtt taaaaatcca ttaacataaa caccccagtc tttaatctgg
     9901 tctgttacaa agctttgtgg ttgtattcta tccacccatt taggtgtgtt tttaacatca
     9961 taaacattta tttttccagt ttctgcatca acagtggcta ttcctgttgc atttgctcct
    10021 ccatagccaa ttttatgttc atataaactt acaacccaat aaggtcttcc ttcatcattt
    10081 atttcaagag tgaaatctgt cataccaaca tttacaatac catgtatgta taaatgtctt
    10141 tgtaaatcct gatgtaagta ggcttctggt tggtaaacta tctttattgg ctttccatct
    10201 atttcttgaa ctaattggac gtcttgagga ttactagctg atacttttac ataaccactt
    10261 gtaccactta gagatgttat ccatttaatt atgtctctgt gaacaagagg cgctacccag
    10321 tacaactctc catctacatt ttgtatatga aattttccta atttggatac actccctatt
    10381 gcaggaactt ctccaagctt tttgtcacct aatttcattg ccatatcttc atctacaaga
    10441 cgaatgtcat ttacactgac agggctaatg tcatcagtaa atttactttc agttactttt
    10501 cccaatagtt ctctatatga ttttgcatga agtacaggtg tagaagttat aaagggaact
    10561 actacaatat acacaagcaa agctattgct attgaaaaat tatatttagc cattttagat
    10621 gctctttcat ttctatctaa catcatatct agtattcctg ctacaacaaa gaaaattatt
    10681 cctactgaaa ataaagatgt aaaatctaat cttagtacag gtaatttaat aaatgaataa
    10741 attattacaa ttattaatgc aactccatat gttttaagat atcgtttcat ttaatactcc
    10801 tctctaaaaa atgttattat tactattata tccatatatt tacaaaaaat aaatatttat
    10861 catatttatt atatattaag atatctttat atatttatag ttctgcttat tcaactatat
    10921 ttaacattat acgtgtatgt ataaatactt tttatacact gtttgtgcta tccatcccgc
    10981 acctaaagga gtgggatttt tgcactattc tgtattatat atatccaaaa atattataaa
    11041 aatacaaata ttagcagaaa tttaaaaact gaagaaagta ttctaactaa gatttacaaa
    11101 ttcttaatcc tatcgaagtt aaactactat cttcagccta attatctagc aatatttttt
    11161 tatatgaaaa actctaaatc aagtttttaa atgtttgcga tttttgatac ataagaatgt
    11221 tgtctagaat tatattctga taataaacct tcatactcta aggttaagcc agataaatta
    11281 taaaaatcat ttggcgttac ttcaaatgct tgtttattta aaatgtctat ctcacttttt
    11341 tctaacatgt cagcaacaaa atttgaacat acatatttat attcagattg tctctgaata
    11401 ttcattagta aatatattaa tgccattgta tcgtaatagt aatcttctct ataatcacta
    11461 attaatttta tatttttata tagattttca tattgtaaat tatctacttc taacgaatat
    11521 accctacaca cagtgttttt tcttatagca tataatcctt gatttatatt ttcttcaaca
    11581 aatcctccaa taaatggatt ccttggattt agccttccaa aagaatacat tggttttaga
    11641 ttttcattta atgatattga cacatgtgta tacagctttt tacttatatt ccttattaag
    11701 taagataata tagttcctgt atatgttgtt acaatataga ctttattcat catttccccc
    11761 caatctagta actaaataat attatacact tacaatttaa tatcataaga tattctaaca
    11821 taataaatgt ggttttacaa attttgattt taaggtactt taatattata taatataata
    11881 aaaatataaa tataagtttt ctatattttt aaccaacaga tgttttcttc aaattaatca
    11941 gatgatttag tatatcttga acctttccag agtcctttaa atatcctaat gctccattta
    12001 tttgtgattt taaatctatt tctacttcca tatccaaatc aacatttcct ttttttatag
    12061 atatattttt aagtgttatt gggtaaagat aacttttttc caaagtaatc ttatttccat
    12121 taacctcaaa tggaactttt ttattgtagt tacttaatat tttttctagc attttatcac
    12181 ttagtttaaa ttttccaatt ttcacattct caagacttac aactaagttt ccatccttta
    12241 aagtaggtct caattcaagt tcatattgac tatttaccaa accaaatacc ttatatggtc
    12301 ctgctacctt tattttacca tttttcattt caacaaaatt attttcaagt tcattaattc
    12361 catgcttctg catcaatgta tatattaaat ttttaaactc ttcctctgaa acagatattt
    12421 ttccaaccat tctaagtgga ttttttacta cctccataga gtttatatat gagccttttg
    12481 ataaatattc ttcatctatg attttattat tttgtgaact aacatcatat ctttcttttg
    12541 gtgtcaagat atatacaaca attcctgtaa gtactaaaac aataacaatt aaacttaaca
    12601 aaatctttgc aacctttccc ataatcgtct cctttacaaa tctgtcatca gatttaaaat
    12661 aaatttagat aactaacttc acataatatt cttaacaata tacatactat aatacagtct
    12721 tttaaaaatt aattcaacca atctaatgtt ttgtaaataa actgtaaaaa catgttttta
    12781 gtataaaagt taatattttg cataatactc ttaattacac ctttattttt ttctaatctt
    12841 ggattaaaat taatattatg caatacagtg tagtgttctg tattataatc aaattaaata
    12901 ggaggtatag aatatgtcaa atgaaacgaa ctcatctaac tttataaaga atattattat
    12961 aaatgacctt gaaacaggaa aacatgacag tatcataact cgttttccac ctgagccaaa
    13021 cggatattta catattggtc atgcaaaaag tatatgtctt aattttggat tagctaagga
    13081 gtttaatgga aaagctaatt taagatttga tgatacaaac ccattaaaag aggatgttga
    13141 atatgtagag tccataaaag aagatgtaaa gtggttagga tttgattgga acgagttaaa
    13201 ttttgcatct aactactttg atgaaatgta taagagagct ttaatactaa taaaaaaggg
    13261 taaagcttat gtatgtgatt tgacacaaga ggaaatgaga gaatatcgtg gtactctaac
    13321 tgaaccagga aaagaaagtc ctcatagaaa cagaactatt gaagaaaacc ttgatttatt
    13381 tgaaagaatg aaaaatggtg aatttaaaga tggtgaaaaa acattaagag ccaaaataga
    13441 tatgtcttct ccaaatataa accttagaga cccaattata tatagaatat ctcattcaac
    13501 acaccataat acaggagata aatggtgcat atatcctatg tatgcttttg ctcatccaat
    13561 tgaagatgca attgaaggaa taactcactc tatatgtact ttagagtttg aagaccaaag
    13621 acctctttat gattggtttg ttaaagaatg tgagatggaa aatataccta gacaaataga
    13681 atttgctaga cttaatataa ataatactgt catgagtaaa aggaaattaa aacaacttgt
    13741 agatgagggt attgttgatg gttgggatga ccctcgtgtt cctacaatat ccggaatcag
    13801 acgtaaggga tatactgcag aagcattgcg caatttctgt agtgaaatag gggtatcaaa
    13861 agttaactct acggtagata gtcaaatgct tgattatttc ctaagagaaa acttacaacc
    13921 aaaggctcct cttactatgg gagttttaag acctttaaaa cttattataa ctaattaccc
    13981 agaagataag attgagatgc ttgaaataga gaataatgct aaagatgaat ctcaaggaaa
    14041 gagattagtt cctttctcta gagaattgta tatagaacaa gatgatttta tggaagaacc
    14101 tgttaagaaa tattttagat ttttcccagg aaatgaagtc cgtttaaaag gtgcttattt
    14161 tgtaaaatgt actgatgtaa ttaaggatga aaatggaaat gtagttgaaa tacatggtac
    14221 ttatgaccct gaaactaaga gtggctctgg ctttacagga cgtaaggtaa aatctacaat
    14281 acattgggtt gatgctaaat cagctatacc atgtgaattt agattatttg aaccattaat
    14341 tcttgatgat atacctgaaa atgaaggtaa acatttctta gaacaaataa atcctaattc
    14401 attggaaata ttacaaggtt ttgttgaacc tacacagata aaagatgcta aaccttttga
    14461 taaattccag tttgttagaa atggattctt tagtatagat aataaatata caactgatga
    14521 aaaatttgta tttaatagaa tagttcctct aaaaagttct tttaaaccag gtaaataatc
    14581 ttacaatcaa aaaatgaaga cttaaaatat aaattacttc tactataaat aaacttagtt
    14641 agaagtaatt ttttatttga gtcttcatca tttactttaa atgattaact tttttcacta
    14701 cagattccca tgacttctat tccatctttt atgcattcta tgttaagagg aaaatctggt
    14761 cctttttctc cgtcaatatc tgttataagt gaatcttcac attctatatg caccttttta
    14821 gttttaaagt atagtatttc atttccatta tattgatcta aataatcacc tctaagcaca
    14881 cttatcaaaa ctggtattga ttttggtatt ggcattcctt taaaaataat tacatccaaa
    14941 tatccatcat ctatttcagc cttatatgct agatttatat ttcctgctgt tttgccatta
    15001 aaaatcaaca taagatacat atctccatca taatacattt cctcagaaga tacttttatc
    15061 ttaaatttcc tcatatacaa tgcttcttct attcccttta tataataaga aattcttcca
    15121 aatgaatttt ttaagtctgt gtttatcctt tgtgatacat ccgtaaacat accagcactt
    15181 gcaacattta taaagtactt attattgact ttccctatgt ctattttctt tggttttgaa
    15241 tttatgattt catttatagc ttcttttata tcaaatgaaa tttgaagagc atttgaaaaa
    15301 tcatttgcag ttcctgtagg caaaattcca attggaattt ttatgtctaa ttctttcatt
    15361 gcatttacta ctaaatctac agtaccatca ccaccagcta tcaatatgtg ttcataagaa
    15421 ctatcaactt ccttaaatgc attctttaca ggttctttaa tagttaatct atagggtatc
    15481 aataaataat ttttttcttg atataattct atgatagtgt ctaaatttga taatatcttt
    15541 ttttcacctg aattaggatt gtatataagt tttacttttt tcattatttc tccttactca
    15601 ttttattctt ttagtatcca aaatcttcat ttaaaaaaat cacatgtatt ctttctggtg
    15661 ttaattgtct ttttataagt gtataactac agcatattct tcctggactt gaacagtcta
    15721 tacatatacc agtagtctta catccagtat ttgtacttaa tcttttacaa ttggctggag
    15781 cagctattgt ttttgttctt tttatagctt catctacatc tttaactatt ttatttactc
    15841 ctgctataac tattacttta tcaggtccat atatcatagc agcaacccta ttcccattcc
    15901 catctaaatt gtaaagttct ccatcctctg ttatcgcatt agtacttgta aaataagcat
    15961 ctgcagaaaa tgactttcta tatatttctt tcatttcttc tggtttgata tcttttgcat
    16021 atctatcaag aaaattatat ttttctctta taaaatcaat cactcctgtt tcaaataagg
    16081 tcatagaacc tccacatcct actagagaac ctgctttaac tatttcttca atttttttaa
    16141 gaagctcttc tttgttactt actaaatacc ctttcatatt attgttttcc aaagatttta
    16201 ttgttttttc tattcttttt tcattaagcc aatttaaatt ttgatccatt ttaacttccc
    16261 ccttattttt aatatgtact taattattta taaactttat tttctttata agtttatttt
    16321 agtacatcta aaaaaaaata caatataaaa cttaaatagt tttacataat tttttccaaa
    16381 ataacttact caatcaaaaa aggaaagtag atgtactatt ctactttccc tatattgtat
    16441 gtagtattta ttgcctaaaa tctatatatt aattatatgt ttcatattat ataatatcac
    16501 agttaattaa aatgtaatac tatcttcttt ttaaacatat aaattgtatt attaaattta
    16561 atatatccaa cttcaataaa tcttattaat ttgatgaaga agatgctata gctgcacttg
    16621 ttgctgccat tacacatgca atttgaatag caacaacaat atttaaaaat atattattag
    16681 ttatagagcc tatattattc tcatttcgta tcaaatctgc ataaattgaa gctacaatag
    16741 cagaactaat cattactcta ttactttttc ctaaagacca atttccaaag cctttttctt
    16801 ctttaagttt atttgaaaca ttttttatct cttctattat ttcatcttct ctataatcta
    16861 ataatgaaat tgctcctatt attggatatc cataataatt cattttacaa tcattttctt
    16921 taaatgcttt tttaagttca atagtctttt tacatttaag catagttcta tcatcactaa
    16981 ataaaagaat ttgggataat gcttgtaaat catttccttt ataaaaacca ttttcattta
    17041 gaaattcata acatttttct atgtattcta aatcttcatc taaatttttt gaatgaattg
    17101 caataagtgc tatattacaa tagtcatcac tagaagttat aaatggatgt tttttcctca
    17161 tgtaatcata tattattttc atttttgata tacatgtaag ataatccatt ttctctctat
    17221 tttcataaac tattgatgct gtaagtggta aatatgtatc gccccaaaac ttttcacttt
    17281 taagttcttt gtatatatct aaaatcatct taaaactact ttctggattt gattcaaacg
    17341 aaagtagtgt tgccatataa aacatattat atcctctaaa attagagaat aatccagtat
    17401 tttttttaat aagctctatt cgttcttcca ctaatctagg acttattctc ttgttcttaa
    17461 gggtaaatgc aagtgcacaa ctatgttgta tcaatcccat ttgccaagaa cctttaactt
    17521 catttaatgc tttgtaattt tctattaata agtttacttt tccatttata aacgattgtt
    17581 ccatattgcc ctcctagtaa tatatctcat tgtactaata gttttatatt tattatatat
    17641 atattaaata ctacaatcaa tacatattac ttcaaagaac atcattcttc aacaataatg
    17701 tagccttttt tgtaatgtct tcccatatta ttgactctat catagtactc tgattcactt
    17761 tcattactcc atttgggcac aaatacatct attgcattag aattactaaa atacttacta
    17821 gaccccctat ccataacagt ttttaatttt ccatctacaa taatcttagt tccaaaactt
    17881 aagtgattgt ttgctacaaa accatcttct aaatcatctc ctgtagcagt tatcgctcca
    17941 tatccatttt cttgattaag acttgtgtaa taactaactt caaaagttat aggtactaac
    18001 ttctttattt taatacctaa ctgattttgt agtttctcct tttgtacttt caacttatac
    18061 tcatcactat ttttataatc ttccatacct tgattatact tggaattaaa gcttttacct
    18121 gactttacta tagtatctat atttactata gattctttac aatgatctgc atctattttt
    18181 gtttctccat ttaccaataa tggagttaaa catacactac atacaacaca tgtaatcaat
    18241 gcttctttaa gcttcataaa ttcccccctt attattttga tatattagca tatttaatat
    18301 tatatgtcta catttagatt taaataccac acccatttgc tttaagaagt tgtcttatat
    18361 ttaattcacc ttaaacactt ataaatcctc tatcttagaa tcatatagaa taaagctttt
    18421 atctttaaat attttttatt aatcttttaa aatctaaaac tac
//
LOCUS       DAFAZV010000066        18160 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFAZV010000066 DAFAZV010000000
VERSION     DAFAZV010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 18160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18160
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.066"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            488..1348
                     /locus_tag="KOU88_003498"
     CDS             488..1348
                     /locus_tag="KOU88_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK3213331.1"
                     /translation="MKIIQILNNNVALVKRGKNEIIVFVKGIGFKKRVGQVINENEIE
                     RTYILDSYDMLEHFSYLLQNSDSNNIVLINEIIEYGEKALNIKSSDYLSLTLLDHLEF
                     LLKRCEKNQFIKSPLVWNVKRFYPKHFEIGMHALKLIGDSKGLNLPDDEAVSIALHFV
                     NMEVNKESHDSTIVELRTLADIVSIIKYHFNVELDETSTNYMRFTTHLQYFIQRIMSD
                     EASIDEDNSIDLYKQVSQLYPKSFGSVQKIRKYIKSQFNVDISISEETYLMLHINRVT
                     QRLEAKSDEI"
     gene            1338..3209
                     /locus_tag="KOU88_003499"
     CDS             1338..3209
                     /locus_tag="KOU88_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3213332.1"
                     /translation="MKYKDLNENIIKLIGGKENIKSVAHCVTRLRFTLNDRSIAQTEE
                     IKKLKGVIDVVSNDVAYQIIIGTHVVDVYNEFMSMIGLSSSESSIKSERKKGIRGIKG
                     IFNSIFVVVSETMTSVIEVLLAAGILASMLALLNMSGILQSDSPTYQILDTLRSATFH
                     FLPVLIAIASAKRLNVNPYIAVVLAVTLLSSSIDGVEGLSLFGINLQATTYANSFIPI
                     LLGVWAMGIIIEGLKKILPKALHYFLVPVLSLIITLSITLTVFGPIGMWIGDGLNYAC
                     MFLIDTLGNWSVVALYAALQPLLIVFGAANFTMPISLNSVTTLGYDPIFMGAATISDI
                     AVCGAMFGYFLKTRNKEQKQLFGTVSFSALMGVTEPSVFGVFMKYRRPFVAVMIGGGI
                     GGLIAGLAQVKTYGMVWGLAALPTYLVGGEVSNFTFMIISVVVSFVAATAASYLLGIP
                     SDEKEEVKGDNEKELELIINENNSRTISIGNVAKGQVIALGEVNDKAFSSGALGKGVG
                     VIPSESKSTVISPVDGTITIVFPTKHAYGIVTDEGLEILIHIGIDTVNLDGKFFESLV
                     TQNQRVKKGDALAVFESDKIIEEGFDSTIITVVTNTSDYLDVISSNDESEELLTVIV"
     gene            3229..4683
                     /locus_tag="KOU88_003500"
     CDS             3229..4683
                     /locus_tag="KOU88_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBK3213333.1"
                     /translation="MNIKDTFFWGGSIAAHQCEGSWDSDNKGPAIMDFVTKGSYETPR
                     VITDKIEEKLDYPSHNGIDFYNRYKEDIALFKEMGFSALRISIDWSRIFPNGDDENPN
                     ELGIKYYEGLIDTLIENNIEPIVTLYHFELPMNLVHKYGSWNNRKLIDLYLKYSETVI
                     RRFDDKVKYWVTFNEMNHIDPQTEHSDIFTYMIAGIKYSEIENKVQTLANVGYNMTLA
                     GVKVAKLAREINPNNKVGCVFGLNPIYPYNCNPSNVLNAFLDNDRDYYQIDAMCNGKF
                     PQYKLKEYEKNNITIEVTDEDKKAFKEGKLDFIGLNYYFSSVSTPKENLSGDKSLFGG
                     IQNPYLEQSKWGWAIDPIGLRFTLNYIYRKYQLPILITENGLGAYDKIEEDGTINDDY
                     RIEYLSKHLSQMKSAIEEDNVECFGYLMWGPIDLVSATTGQMSKRYGFIYVDLDDEGK
                     GSFKRYKKKSFDWYKEVIKSNGEVLDFSTDIVVG"
     gene            5708..6916
                     /locus_tag="KOU88_003501"
     CDS             5708..6916
                     /locus_tag="KOU88_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213334.1"
                     /translation="MENFWNPLTCFTVCVMIYAFSEFLSKKTKGAISTLLFVCIIFLI
                     GFWTNILPKDITGASGILAAMSNFGIALLITNLGTLINLEDLCHEWKTVVIALVGIVG
                     IGVGCLTVGSMLFGREYALIAAPPIAGSTVAGIIVTTVAEAANRPELAAFVILVLSFQ
                     KFFGIPITTYCINKELKFKRDNGDFLKDESKSNFKLPSMRIFKEDLGKKSSTLVYLAK
                     LSFVAMIGNFVGLATLIPGFTPANYYLNPNIACLLVGLIFTRIGFLEKGILDKSQSNG
                     IIMFGCMLMLPGGLAKVTPTALFGMIVPTIGILVVGSVFIILFTAIVGKLLGYSPRMS
                     AAIGVTCMLAYPATQIISNEGIDAMEGTEEEKQRATDYLLPKMIIGGFVTVTIASVAF
                     ASIIGPIIFG"
     gene            6947..8326
                     /locus_tag="KOU88_003502"
     CDS             6947..8326
                     /locus_tag="KOU88_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3213335.1"
                     /translation="MIGSISINEIDKKRFKLDDLSKKIWENPEKAFKEFKACENTANF
                     LRSEGFDVEVGVGGLATAIRASFGSGKPVIGFMGEFDALPGLNQKVSTKQEAFELGAY
                     GHGCGHNLLCTAHVGAVVGLKREMIENNLSGTIVFYACPGEEQLTGKGFMARGGAFEG
                     LDLAINFHPNKISEATIGTSTAVNSVKFHFKGKTAHAGSDPQNGRSALDAVELTNVGA
                     NYLREHVTSDVRIHYTITDGGVAPNIVPDKASVWYYTRALSREAVESTYERLVKVAKG
                     AAMMTETEVEVEFLGGCYNTLNNHVLANLVSECMNEIKQEPWTREELDFAAELDRQSP
                     QQYKAMISKYNLPEGTHLYYGGGNVTNFNSYGSTDIGDVMHIVPTAYFFTGCTNLGAP
                     GHSWQFTSCAGSSIGEKGMIYASKIMAMFGAKILNNPEIAKKAKEEFDKSMNGKTYKC
                     PIPDDIPTP"
     gene            8432..9622
                     /locus_tag="KOU88_003503"
     CDS             8432..9622
                     /locus_tag="KOU88_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3213336.1"
                     /translation="MKNFFKEAQSIEGEIIRWRRYLHENPEIGCNIPKTVTFVTSTLE
                     KMGYSPKLTSNNGIVAVLDSENGGKTLLLRADMDALPIMEETDLPFKSKNKDASHSCG
                     HDNHTAMLLGAAKILMDNKHLLKGRVKFVFEPDEETTRGAKSMIDDGILENPQVDAAM
                     AFHSMVGKFLNTGQVAYSRGPAMASADIFEITVEGKATHGASPEFGVDPINIMSHIQI
                     ALNTILSREKPQKEPVVLTIGMFNAGNVPNAIPNKASMSGTLRTFDQFVREKLKNRII
                     EISTGIAKSFGGNAKVEFKMGTPAVINDLDVGDEIVSYVKEVIGNENVIDFPSAMGSE
                     DFSEILLRVPGVFLWIGMGSISQGYNFGMHNPKAIFNEEGLVYGSALFAHCAVKWLEN
                     NFSR"
     gene            complement(9750..11078)
                     /locus_tag="KOU88_003504"
     CDS             complement(9750..11078)
                     /locus_tag="KOU88_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213337.1"
                     /translation="MMKIAVITTEFLKEFVDNSIKKLNINAEIEIYIYRDFSHVGDLY
                     LEIEDRFDGFAVSGPIPKKAITKKAGTIKKPLVDFGTDLQSYYDMFLKLIFKYNTLDF
                     SRAYFDLTDWADNPKDISYYLSNGTFGDLMDSIDENASKMSLSDIAKLEKKIAKKHIN
                     LWNEGKIDFSTTRFSSIVPMLQNAGVNFHFIYPDIDLLKNTFNNLIKDIHLHRMKGNQ
                     PSVIYITVKDTNYDDSTLDQVYKILNSIKKDKLTDFIIEKNSNSFKIFTKCETIKSLT
                     KNFTACYIKESIENSTNIKVCVGYGIGNDIKQAMSSAISANKESKINHLNYSFLVNEN
                     YETIGPLLCDKLLTVSNKVTPHINTIAKSSKLSTLTIQKIISVTEILQRDEVTPKELS
                     SCLNVTVRTANRFLSSLLKSGNATILYEKQNSTKGRPERVYKLFISENKY"
     gene            complement(11696..12910)
                     /locus_tag="KOU88_003505"
     CDS             complement(11696..12910)
                     /locus_tag="KOU88_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBK3213338.1"
                     /translation="MRNCIIAQSGGPTAVINASAVGIYEKNLETKYFDKVYFGINGIE
                     GILNKNIIDSDSLNKDNVLNLKQTPSSGLGSCRYKLADYKINSYDYDRVINILDEYKI
                     DTLFYIGGNDSMDTVMKFSQYCKNTTCKIKFIGIPKTIDNDLLGTDNCPGFGSAAKLI
                     STLIMETYLDFSIYKNNGIFIVETMGRDTGWLAASSSLARLNDTPLVDLIYLPEIDFY
                     EDKFIEDVRKIFKEKNKAYIVASEGIRDKYGNFICEQKTSAHDKFGHSQLGGVSNYLK
                     NLIVSSSITTRVKTLELGVIQRCAMHLASDTDLKQAAEVGAYGIELSKKGYTGVMAII
                     NRTCNNPYKYEVSHTDISKIANKTKYFPKEWINEECNYITNEALNYLYPLIQGKPDIK
                     YKNGLPYFSIIY"
     gene            13336..14052
                     /locus_tag="KOU88_003506"
     CDS             13336..14052
                     /locus_tag="KOU88_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentose-5-phosphate 3-epimerase"
                     /protein_id="HBK3213339.1"
                     /translation="MKHIKIAAGLAHVNYGHISAVVKEAMDAGVDYVHSDAADMHDLK
                     NMQLMGGHQIIEAIRPVTDKPIECHIYTRDCDRLFIEKIAAAGCNLLIIPAEHFLGAP
                     LAYIINYCREFGMKVGLTIGCYTPLCFVDEAIYDIDRLQIVVHGVDETDGKDNWGWRK
                     SAVDLVKRARKMIDEKNPKCELAIDGGLRSDNMEPLIECNPDVVILSSAIFKDKDGIT
                     AGVKNCRKAIDEAATKFGLE"
     gene            14187..14813
                     /locus_tag="KOU88_003507"
     CDS             14187..14813
                     /locus_tag="KOU88_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK3213340.1"
                     /translation="MKKEMIKDYLLITISAFLMALAVNFFFAEHTLAPGGITGLSVVL
                     STFLSMPVENISLGISMPLLVMGLLFLGKGFGIKTLYITLMGPLFLKVIPQTHITDNL
                     LVAGVIGGLLVGTAIGIAIIRGCSTGGTDLVAMLINKVIKFLKLPVILFMLDGFIIVA
                     SGIISKNFMISIYSLISLLLIIKTIGFVTTKFGKNTEEINNINNACAQ"
     gene            complement(15026..16570)
                     /locus_tag="KOU88_003508"
     CDS             complement(15026..16570)
                     /locus_tag="KOU88_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3213341.1"
                     /translation="MNKRLLDIAELLLNSSDYITVDTIAEELKVSNKTIRNDLVILDE
                     WLLEFNLSLDKKTGSGVIILGNEDIKLKVIRDINDKSNCIYAYSPEDRKRYILSKLFI
                     KNSKFRIRDICNELHVSRATVHKDLVVIQNFLQNFKVTLVRKTNNGVYLEGKEKDIRK
                     AIFELATVNKSYTELKEILFSKSNECKDTPSTKIFKELFNYDFEKLSQITLHTLQVEK
                     SNLSDEYYINFLIHIAICIKRISIKRYINLSEGFFRELLEHEYFEKSKILCANLSEAF
                     DVEFIDEEVCYILLHIEGLLKSIKKTTTLEPLKNEEITEYNLSEAIAVHWGSILNLNL
                     KDDLILIKSLANHLKSVLHRINYGFTITNPILNDIKRTFPYTYKAAKESNTVIKQLMN
                     YEVNDDEIGYLALYLISAIDRSKSPLNTILICHCSDGVSNLLVQKLSFEFNQINIVKS
                     IPLSSISFTNFDDVDLILTTAPVDFEHNAELININALLSKNDISRLSTIIKKLYSEKN
                     KILSYK"
     gene            complement(16596..17237)
                     /locus_tag="KOU88_003509"
     CDS             complement(16596..17237)
                     /locus_tag="KOU88_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HBK3213342.1"
                     /translation="MKYLIDSANLDEIQKCLKYGFKGITANPSMYLKEKVNFHEFIET
                     CANLNPEILTAEVIGNNLYELINSCDKILNINKNTIIKINFSEVGLELINILNSKGVK
                     TACTLIFNVNQASLAINAGADYLFPFIGRNDENGNDGIKNLTEICNLISINGYNTKVV
                     AASIKNVFHLTQASLCGCDYAAVTYDLFKKASFNQLTIDGANTFERDWSKVNK"
     gene            17507..17698
                     /locus_tag="KOU88_003510"
                     /pseudo
     CDS             17507..17698
                     /locus_tag="KOU88_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422425.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
BASE COUNT         6731 a         2149 c         3006 g         6274 t
ORIGIN      
        1 atttaaatga aactaaattt gaagctttac ctattaatat atcttaatag tgattaaata
       61 aaactaaact taagacttta tatgttaata tatcttaaga atttatttgt taacatacag
      121 ttcattatat ttaaaagcat tactatgata attcataata gtaaaataga taatggttca
      181 gacaatatta taaatattag tgacggtaaa atagtatcaa tttagtatat aaaccttgtc
      241 agataatcgc ataacagagc ttgtagttat agaataaaaa aatatctagg aaaccgttga
      301 cagatttata tggatagtat aacatataga atatgaaatt aaacaaaaaa gaattttaat
      361 tatggcgacg tagtcataat tttgagtatg ttactgatta gcaggcagaa ctcaagtata
      421 tatgtgaaaa atagagggat actctataca tatatgcttg agttcttttt attgaaggga
      481 ggaatatatg aaaataattc agattttaaa taataatgta gccttagtaa aaagaggtaa
      541 aaatgaaatt attgtatttg ttaaaggaat tggctttaaa aaaagagtgg gacaagtaat
      601 aaatgaaaat gaaatagaga gaacatatat actagattca tacgatatgc tagaacactt
      661 tagttatcta ctacaaaact cagactccaa taatatagtt cttattaatg aaataattga
      721 atatggtgag aaagctttaa atataaagtc aagtgattat ctaagcttaa ccttactaga
      781 ccatttagag tttttactta aaagatgtga aaagaatcaa tttataaaaa gtcctttggt
      841 atggaatgtt aaaagatttt atccaaagca ttttgaaatt ggaatgcatg cactaaaatt
      901 aattggtgat agtaagggac ttaatcttcc tgatgatgag gcagtatcaa tagcacttca
      961 ttttgtaaat atggaggtaa ataaagagtc tcatgatagt acaattgtag agttgagaac
     1021 tttagcagat atagtttcta taataaaata tcattttaat gtagagctag atgaaacttc
     1081 aacaaattat atgagattta ctactcatct acagtacttt atccaaagaa ttatgtcgga
     1141 tgaagcttca atagatgaag ataattctat agatttatat aaacaagtaa gtcaacttta
     1201 tccaaagtca tttggaagtg ttcaaaagat aagaaaatat ataaaatcac aatttaatgt
     1261 cgatatatct ataagtgaag aaacttattt aatgttgcat ataaataggg tgactcaaag
     1321 actggaggca aaatcagatg aaatataaag atttaaatga aaatataata aaacttatag
     1381 ggggaaaaga aaatataaag tcggtagcgc attgtgttac tcgtttaaga tttactttaa
     1441 atgataggag tatcgctcaa acagaagaaa ttaaaaaatt aaaaggagta attgatgtag
     1501 tttctaatga tgttgcttat caaattataa taggtactca tgttgtagat gtatataacg
     1561 agtttatgtc tatgataggt ttaagttcaa gtgaatcaag tataaaaagt gaaagaaaaa
     1621 agggaattag aggtatcaaa ggtatattta attccatctt tgtggtagtc tcagagacta
     1681 tgacttcagt aattgaagta ctacttgcag ctggtatact tgcaagtatg ttagcacttt
     1741 taaatatgtc tggcatactt cagagtgaca gtcctacata tcaaatatta gatacattaa
     1801 gaagtgctac atttcacttc ttaccagtat taattgcaat agcatcagca aaaagactta
     1861 atgtaaatcc ctatatagca gtagtgttag cagttacgtt attatcttca tcaatagatg
     1921 gtgtagaagg attaagttta tttggtataa atttacaggc tacaacttat gcaaacagtt
     1981 ttattccaat acttttagga gtatgggcaa tgggaattat aattgaaggt ttgaaaaaaa
     2041 tattacctaa agcattacac tattttttag ttccagtatt atctttaata ataactctat
     2101 caattacatt aactgtattt ggacctattg gtatgtggat tggtgatgga ttaaactatg
     2161 catgtatgtt tttaattgat acattgggta attggagtgt tgttgcactg tatgcagctt
     2221 tacaaccact cttaatagtc tttggtgcag caaactttac tatgcctata tctttaaatt
     2281 ctgtgacaac attggggtat gacccaattt ttatgggcgc tgcaacaata tctgatattg
     2341 cagtttgtgg tgcaatgttt ggatatttct taaaaactag gaataaagaa caaaaacaat
     2401 tatttggtac agtaagtttt agtgcactta tgggagttac agaaccttca gtgtttggtg
     2461 tgtttatgaa atatagaaga ccatttgtag cagtaatgat aggtggaggt ataggtggtt
     2521 taatagcagg tttagctcaa gttaaaacat atggaatggt ttggggatta gctgcattac
     2581 caacatatct tgttggagga gaggtatcta actttacatt tatgataata agtgtagtag
     2641 tatcatttgt agcagcaaca gcagcttcct atttactagg aataccttca gatgaaaaag
     2701 aagaagttaa gggtgataat gaaaaagaat tagaactaat aatcaacgag aacaattcaa
     2761 gaactattag tattggaaat gttgcaaaag gtcaggtaat tgcacttggg gaagttaatg
     2821 acaaagcatt ttcatctgga gcattaggta aaggggttgg agttatacct agtgaatcaa
     2881 aatcaactgt tatatctcct gtagatggaa ctataactat agtatttcca actaaacatg
     2941 catatggtat agtgactgat gaaggattag aaatattaat tcatattggg atagatactg
     3001 taaacttaga tggaaaattc tttgaaagtc ttgtaacaca aaatcaaagg gttaaaaaag
     3061 gagatgcttt agcagtattt gaatctgata aaattataga ggaaggcttt gattctacta
     3121 taataactgt agttacaaat actagcgatt atttagatgt aatctcatca aatgatgaat
     3181 cagaagaatt attaactgta atagtataaa ttttaggagg gaaaattcat gaatattaaa
     3241 gatacatttt tctggggagg aagtattgca gcccatcaat gtgaaggttc atgggatagt
     3301 gataacaaag gacctgcaat tatggatttt gtaactaagg gctcttatga aacgccaaga
     3361 gtaattactg ataaaataga agaaaaattg gattatccat ctcataatgg aatagatttt
     3421 tataatagat ataaagaaga tatagcttta tttaaagaaa tgggatttag tgcattaaga
     3481 atatctatag attggtcaag aatttttcca aatggagatg atgaaaatcc taatgaatta
     3541 gggattaaat actatgaagg tctgatagat acattaatag aaaataatat agaacctatt
     3601 gtaacactat atcattttga attacctatg aatttagtac ataaatatgg ttcatggaat
     3661 aacagaaaac ttatagattt gtatttaaag tacagtgaga ctgtaataag aagatttgat
     3721 gataaggtaa agtactgggt tacatttaat gagatgaacc atattgaccc tcaaacagag
     3781 cactcggata tttttactta tatgatagca ggtattaagt atagtgaaat agaaaataag
     3841 gttcaaacat tggcaaatgt agggtataat atgactttgg cgggtgtaaa ggttgcaaag
     3901 ttggctagag aaatcaatcc caacaataaa gttggatgtg tatttggact aaatccaatt
     3961 tatccataca attgtaatcc tagtaatgtg ttaaatgcat ttttagataa tgaccgtgat
     4021 tattatcaaa ttgatgcaat gtgcaatggg aagtttccac aatataaatt aaaagaatat
     4081 gaaaaaaata atataactat tgaagtgact gatgaagaca aaaaagcatt taaagaaggt
     4141 aagttagatt ttataggact taattattat ttttcaagtg tatctactcc aaaagaaaat
     4201 ttatcaggtg ataaatcttt atttggtggg attcaaaatc catatttgga acaaagtaag
     4261 tgggggtggg caatagaccc tataggttta agatttacct tgaactatat ttacagaaag
     4321 tatcaattac ctatcttaat tacagaaaat ggtttagggg catatgataa aatcgaagaa
     4381 gatggaacta taaatgatga ttatagaatt gaatatttaa gtaagcatct atctcaaatg
     4441 aagtctgcaa ttgaagagga taatgttgaa tgttttggat atttgatgtg gggaccaatt
     4501 gatttagtca gtgcaactac aggtcagatg agtaagagat atggatttat ctatgttgac
     4561 ttagatgatg aaggcaaagg aagttttaag agatataaga aaaaatcatt tgattggtac
     4621 aaagaagtaa taaaatctaa tggagaagtt ttagattttt ctacggatat agtagtaggg
     4681 taggaataag ataaatagaa gttaggaact aatgttaatt agtgtctagt aaagcattta
     4741 aaatagagta tagggtcttt aaagtaaagt gtgtattctt cttaaaagta atggcaacta
     4801 aaattactat aaaaaggaga atacacattt tttatgttta tacttaagta aatatttaga
     4861 catattcata gtataattta ctcattatat aaaaatagta tgatttactc actatataac
     4921 tttataaatt ttctggaaaa atgtcagaat atattgacaa agaaaagatt taaaattata
     4981 atctatatta agaatagttt gacaatataa aaacaagtat ttttataaat agtgaaatta
     5041 tttttattgt aaatttaaga ataatttagg actactataa agataaaggt atagatgtca
     5101 ttatatgata aatcatactt gtatagaaag aattttaaag tatggcttat cattgattta
     5161 atataataaa taatttttgt ttctagtaat agttcctagg aataagatat ctaaattcgt
     5221 ttagaaatag tctaatttac aaaggagggg atgcactaat agataaaatt tctatataaa
     5281 gaagacttaa agtgaagtat attctgataa tattggttta atgggtatat tattatttcg
     5341 ttttagatat tttaagaata atttaagacg tttgcaaaaa tgtattctat atctaatatt
     5401 taaataaata taagtcttcc aacatgtata ctaatataga gagtagttga agtacaattc
     5461 taactcgtaa aattatgtag aaagtaaaaa tcaaaaagaa atctagtaag ttgataacta
     5521 tagttaatat ttagagagtt aactctagtt atatttattt agatatttta ggaataattt
     5581 aggacgcata taatatcatc aaaaaatatc aagctatacc atatgtagtt aagaataact
     5641 gcataatata cattttataa ttattgtttt attgataaaa aattattata tttaggagga
     5701 aacaacaatg gaaaattttt ggaatccact tacttgcttt actgtatgtg taatgattta
     5761 tgcttttagt gagtttttat ctaagaaaac aaaaggtgca atttcaacat tgttatttgt
     5821 atgtattata tttttaatag gattttggac aaatatttta ccaaaagaca ttacaggagc
     5881 atcagggata ttagctgcaa tgagcaactt tggtatagct ttattaataa ctaacttagg
     5941 aacacttata aatcttgaag acttatgtca tgaatggaaa acggttgtaa ttgcattagt
     6001 aggtattgta ggaatagggg ttggctgttt aacagtgggt agtatgttat ttggtagaga
     6061 gtatgcttta atagcagcac ctccaatagc gggttctact gttgctggta ttatcgtaac
     6121 aactgttgca gaagctgcaa atagacctga acttgctgca tttgtaattc tagtattatc
     6181 atttcaaaag ttctttggca ttccgataac tacatattgt ataaataaag aattaaaatt
     6241 taaaagagat aatggggatt ttttgaaaga tgagtcaaaa agtaatttta aacttccaag
     6301 tatgagaatt tttaaagaag atttaggtaa aaaatcatct actctagtgt atcttgcaaa
     6361 gctttcattt gttgctatga ttggtaattt tgtaggattg gctactttaa taccaggatt
     6421 tacccctgca aactattatt taaatcctaa tatagcatgt ttgttagtag ggttgatttt
     6481 tacacgaata ggttttttag aaaaaggaat tttagataaa tctcaatcta atggaattat
     6541 aatgtttggt tgtatgttga tgttacctgg aggacttgct aaggtaactc caacagcatt
     6601 gtttgggatg attgttccaa ctataggaat acttgttgta ggctctgtat ttataatatt
     6661 atttactgca attgtaggaa aactattggg atattctcca agaatgtcag ctgcaattgg
     6721 tgtaacttgt atgctagctt atcctgcaac acagataatt tccaacgaag gtattgatgc
     6781 tatggaagga actgaagaag aaaaacaaag ggcaacagat tatttattac caaagatgat
     6841 tataggagga tttgttactg taaccattgc atcagtggca tttgctagta taataggtcc
     6901 aattatattt ggttgatagt aaatatactt ataggaggaa taggaaatga taggaagtat
     6961 atctataaat gagatagata aaaaaagatt caaacttgat gatttaagta agaaaatatg
     7021 ggaaaatcca gaaaaagcat ttaaagaatt taaagcatgt gaaaatacag caaactttct
     7081 aagaagtgaa ggatttgatg tggaagtagg tgtaggaggt ttagccacgg ctattagagc
     7141 tagttttggt tcaggtaaac cagttatagg ttttatggga gaatttgatg cattacctgg
     7201 tttaaatcaa aaagtttcaa caaagcaaga agcatttgaa ttgggtgcat atggtcatgg
     7261 atgtgggcat aatttattat gtacagcaca tgtaggggca gtagtagggc ttaaaagaga
     7321 gatgatagaa aataacttaa gtgggactat agtattttat gcatgtccag gagaagaaca
     7381 attaacaggt aaaggattta tggctagagg tggagcgttt gaagggttag acttagctat
     7441 aaattttcat ccaaataaaa ttagtgaagc tacaattggt acttcaacag ctgttaactc
     7501 tgtaaagttt cactttaagg gaaagactgc gcatgcaggc tcagaccctc aaaatggaag
     7561 aagtgcacta gatgctgtgg aacttactaa tgtgggagct aattatttga gagaacatgt
     7621 tacttctgat gtaaggattc attatacaat tacagatgga ggagtagcac ccaacatagt
     7681 tcctgataaa gcatcagtat ggtattatac aagagcttta agtagagaag ctgtagaaag
     7741 tacatatgaa agacttgtaa aggtagcaaa aggagctgca atgatgactg aaactgaagt
     7801 tgaagtagag tttttaggag gttgttataa tactttaaac aatcatgttt tagcaaatct
     7861 tgtatcagaa tgtatgaatg agattaaaca agagccttgg actcgagagg aattggattt
     7921 tgcagctgaa ttagatagac aaagcccaca acaatataag gctatgataa gtaaatataa
     7981 tttgccagaa ggaactcatc tatattatgg tggaggaaat gttacaaact ttaatagtta
     8041 tggttctact gatattggag atgtaatgca tatagttccg acagcatact tttttacagg
     8101 gtgtacgaat ctaggagcac caggtcatag ctggcagttt acatcttgtg caggaagttc
     8161 tataggagaa aaaggtatga tatatgcatc aaagattatg gctatgtttg gagctaaaat
     8221 attaaataat ccagagatag ctaaaaaggc aaaagaagaa tttgataaat ctatgaatgg
     8281 taaaacatat aaatgtccta ttccagatga tattccaact ccttaaaaag acatgaaatt
     8341 taatatataa aattataatt tttatatcag catcatttca ttactaaaag aaagtgagat
     8401 tttgttgact atctgattag gaggaaggaa tatgaaaaat ttttttaaag aagcgcagtc
     8461 aatagaaggg gaaattatta gatggagaag atatttacat gaaaatcccg aaattggttg
     8521 caatataccg aaaacagtaa cctttgttac cagtacttta gaaaaaatgg gatattctcc
     8581 gaaattgacg tctaataatg gaatagtagc tgttttagac agtgaaaatg gtggaaagac
     8641 cttattatta agggcagata tggatgcact tcctattatg gaggagacgg atttaccttt
     8701 taaaagtaag aataaagatg catctcatag ttgtggacac gataatcaca cagcaatgct
     8761 cttaggagca gctaaaatac ttatggataa taaacactta cttaaaggta gagtaaagtt
     8821 tgtatttgaa ccagatgaag agactaccag aggtgcaaaa tcaatgattg atgatggtat
     8881 attagaaaat cctcaggtcg atgcagctat ggcatttcac agtatggtgg gtaaatttct
     8941 taacacaggt caagtagctt attcacgtgg tccagctatg gcatctgcgg atatatttga
     9001 aataacagta gaaggaaaag caactcatgg agcaagccct gaatttggag tggacccaat
     9061 aaacataatg tcgcatatac aaatagcatt aaacactata ctttcaagag aaaaacctca
     9121 gaaagaacct gtagttttaa ctattggtat gtttaatgca ggaaacgtac caaatgctat
     9181 accaaataaa gcatctatgt caggaacttt aagaacattt gaccaatttg ttagagaaaa
     9241 attaaaaaat agaattattg aaatatctac aggaatagct aaatcatttg gaggaaatgc
     9301 taaagtggaa tttaaaatgg ggactcctgc agttataaat gatttggatg taggagatga
     9361 gattgtatct tatgttaaag aagttatagg aaatgaaaat gtaatagact ttccatctgc
     9421 aatgggttca gaagattttt cagagatttt actaagggtt ccaggagtat ttttatggat
     9481 tggaatggga agtattagtc agggatataa ttttggtatg cataatccta aagcaatttt
     9541 taatgaagag ggattagttt atggttcagc tttatttgct cattgtgcag taaaatggtt
     9601 agaaaataat tttagtagat aataacataa aatattatta aatatcataa aaggtatatc
     9661 ttaaaaagat gcaaagatat accttttaga aagtcatata taattttact taatattaga
     9721 tgataaaata tttttatgca ttttggattt taatatttat tttctgatat aaataatttg
     9781 tatacccttt caggtctacc ttttgttgag ttttgttttt catataatat agtagcgttt
     9841 ccagacttta agagactact tagaaatcta ttagcagttc taactgttac atttaaacat
     9901 gaagataatt ccttaggagt aacttcatct ctttgtagaa tttcagtaac agatataatc
     9961 ttttgaatag taagagtaga caatttagaa cttttggcaa ttgtatttat atgtggagtt
    10021 actttatttg aaacagtaag taacttatca cacagtaaag gtcctattgt ctcataattt
    10081 tcgttaacta agaaactgta atttaaatga tttattttag attccttatt agcacttatg
    10141 gcactagaca tagcttgctt tatatcatta ccaattccat atccaacaca tactttaata
    10201 tttgtactat tttcaataga ttcttttata taacatgcag taaaattttt agttaatgat
    10261 ttaatcgttt cacatttagt gaaaatttta aaagaattac tatttttttc aattataaaa
    10321 tcggttaatt tatctttttt aatactattt aatattttat aaacttggtc tagagtagag
    10381 tcatcataat ttgtatcttt aactgttata tatattacac ttggttgatt tcccttcatt
    10441 ctatgtaaat gaatatcttt tattaagtta ttaaaagtat tttttaataa atctatatca
    10501 gggtatatga aatgaaagtt tactcctgca ttttgtaaca taggaacaat actactaaaa
    10561 cgagtagtag aaaaatcgat tttcccttca ttccatagat taatatgttt ttttgcaatc
    10621 tttttttcaa gttttgctat gtcagataaa ctcattttag atgcattttc atcaatacta
    10681 tccattaagt ctccaaatgt gccatttgat aaataatatg atatatcttt tggattatct
    10741 gcccagtctg ttaagtcaaa gtacgctcta gaaaaatcta atgtattata tttaaagata
    10801 agctttagaa acatatcata gtaactttgt aagtcagtac caaaatcaac tagaggtttt
    10861 ttaatagttc cagccttttt tgtaatagct tttttgggga tagggccact aactgcaaat
    10921 ccatcaaacc tatcctctat ttccaaatat aaatctccaa catgagaaaa atctctatag
    10981 atatatattt caatttctgc attaatattt aactttttta tagaattatc tacaaactct
    11041 tttaaaaatt cggttgttat gactgctatt ttcatcatag attacttcct tttcaattat
    11101 tataattatt ttatattaaa tattacatta atctattgtt ctagttaaaa tcgtatttca
    11161 attaaattca attaaaataa ataactcttt ataaaaagca attatttagg tagaggaata
    11221 tttgctaact ttaatagtct ttgttaactt taattttatt taagttatta tagtcttact
    11281 aattttataa ttgtagattt aactacttta tgttctttta ttgtttatgt agttgattta
    11341 gaagttattt taaccattta ttttaattga agttgtttga cttttaaatc ctttgtgtaa
    11401 tctttgtttt tctagccatg ataaaagtat ttctatttgt atcactatat ataataatat
    11461 catgacaaaa tatttattgt ctaactaatt ataatctatc caaaatgaaa atgggtgtga
    11521 gatattatta caacaaattg tattagtatt aaaaagatta aaaaattaaa aaactaaaca
    11581 gttaaataat taaacgatta agtgactgtc atataacaat ttataatttt atttaacagc
    11641 cacttaggta tttaagagcg atagaattga gtgtatatca aattataata atttcctagt
    11701 aaataattga aaaataaggt agtccatttt tatatttgat atctggttta ccttgaataa
    11761 gtggatatag ataatttagg gcttcattag ttatataatt acattcttca tttatccact
    11821 ctttaggaaa atattttgtc ttgttagcta ttttagaaat atcagtatga ctaacttcat
    11881 acttataagg attattgcat gttctattaa tgatagccat aactcctgta tatccttttt
    11941 tagatagttc tatcccatat gcaccaactt cagctgcttg ttttaaatca gtatctgaag
    12001 ctaaatgcat agcacatctt tgtattacac caagttctaa ggtttttact cttgttgtaa
    12061 ttgatgatga tactataaga ttctttagat agttgcttac tccacctaat tgggaatgac
    12121 caaatttatc atgagcagaa gttttttgtt cgcatataaa gttgccgtat ttatccctta
    12181 taccttctga tgcaactata taagccttat ttttttcttt aaatattttt ctaacatctt
    12241 ctataaactt atcttcatag aaatcaattt ctggaaggta tattaaatca acaagtggag
    12301 tatcattaag tctagctagt gaagaagaag ctgctaacca tccagtatct ctacccatag
    12361 tttctactat aaatatacca ttatttttgt atatagaaaa atctaagtat gtttccatta
    12421 ttagtgtaga aataagcttt gcagcagaac caaatccagg acagttgtca gttcctaata
    12481 aatcattatc tattgtttta ggaataccta taaattttat tttacaagta gtgtttttgc
    12541 agtattgaga aaatttcatc actgtgtcca tagaatcatt tccgcctata taaaataatg
    12601 tatctatttt atattcatct agtatattta taactctatc ataatcataa gaatttattt
    12661 tataatcagc cagtttgtat ctacaagaac caagaccaga cgaaggtgtt tgctttaaat
    12721 ttaatacatt atctttgttt aaggagtctg aatctattat atttttgttt aatatacctt
    12781 caatcccatt gataccaaaa tatactttat caaagtattt agtttctaaa tttttttcat
    12841 aaataccaac tgcagaagca ttgataacag ctgtagggcc tccagattgg gcaataatac
    12901 agtttctcat tttacatctc cctttcatta atattgttat gaatggtact ttttatcgag
    12961 taaatttata tttatagtct gattatatat taaatgaact agctatatca attgagttag
    13021 tatagacaat aaatgccata agaatgtggt aaaaaactaa ctttttatat acaattaatg
    13081 tctataattt accacaatat aaaggtactt ttaaggagta gtcaaagtgt tgtgaaaaaa
    13141 aatatatcag tgtaatatta atttacaaag caaaataagt tcacagttaa caaaagcaga
    13201 ataagttcat aaaagaaata tatacagcaa taaaagtaat gctaaataaa agtaatactg
    13261 gattaaaaaa tattaaaaaa atatcaaaaa ctaatattta atactaatta aagtaaaata
    13321 tggaggtata caaatatgaa acacataaaa atagcagcag gattagcaca tgtaaattac
    13381 ggtcatatat cagccgtagt taaagaagca atggatgcag gtgtagacta cgtacattca
    13441 gatgcagcag atatgcatga cttaaaaaat atgcaactta tgggtggtca tcaaataata
    13501 gaagcaataa gaccagtgac agataaacca atagaatgcc atatatacac aagagattgt
    13561 gatagattat ttatagaaaa aatagcagca gcaggatgta acttgttgat aataccagca
    13621 gaacattttt taggtgctcc tcttgcatac ataataaatt actgtagaga atttggtatg
    13681 aaagtaggat taacaattgg atgttacaca ccattatgtt ttgttgatga agctatatat
    13741 gatatagaca gattgcaaat agtcgttcat ggtgttgatg aaactgatgg aaaagataac
    13801 tggggatgga gaaagagtgc tgttgattta gtaaaaagag ctagaaaaat gatagacgaa
    13861 aagaatccta agtgtgaatt agcaatagat ggtggactaa gatcagacaa tatggagcca
    13921 ttaatagaat gtaacccaga cgttgtaata ttatcttcag caatattcaa ggataaagat
    13981 ggtataacag caggtgttaa gaattgtaga aaagctatag atgaagcagc tacaaagttt
    14041 ggtttagaat aagataataa actatgataa aagagatgct ttcttaatgt tttaaggaag
    14101 cattaatttt atgaaaaact acaggaagct agactaattt aattgatttt ttatactgaa
    14161 acaatataat cataggaggt tattaaatga aaaaagaaat gataaaagat tatttactga
    14221 taacaatatc agcattttta atggcattag cagttaattt tttctttgca gaacatacat
    14281 tagctccagg aggtataaca ggattatcag tcgtacttag cacattctta tcaatgcctg
    14341 ttgagaatat atcattagga atatctatgc cacttttagt aatgggatta ttatttttag
    14401 ggaaaggttt tggaataaaa acattatata taactcttat gggcccatta ttcttaaaag
    14461 taataccaca aactcacata actgacaatc tattagtagc aggagtgata ggtgggttat
    14521 tggtaggaac tgctataggg atagcaataa taaggggctg tagtactggt ggaactgatt
    14581 tagttgcaat gcttattaat aaggtaatta agtttctgaa gttgccagtt atattattta
    14641 tgctagatgg atttataata gtagcgtctg gaataataag taagaatttt atgatatcta
    14701 tatattcatt gatatcttta ttactcataa taaaaacaat aggatttgta actacaaagt
    14761 ttggtaagaa tactgaagaa attaataata taaataatgc ttgtgctcaa taaaaataat
    14821 aaaatttact ttaaatataa aagtttaaaa aatataaaag cttaaataaa aagcttaaat
    14881 aaaaagatta aatataaaaa atggaggtgt ctcaaaatga attttttagt tcatgaggca
    14941 ctttttctat gaaatcaaat atatttttat catttagaca atgaaaaata ggtttatctc
    15001 tatgttgaga caagcctatt tttgtttatt tataagataa tattttattt ttttcagaat
    15061 atagtttttt tataattgta ctaagtctag aaatatcatt cttacttaaa agagcattta
    15121 tatttatcag ttcagcatta tgttcaaagt ctacaggagc agtggttagt attaagtcca
    15181 catcatcaaa gttcgtaaat gaaatagaag atagaggtat agatttaact atattaatct
    15241 gattaaattc aaaacttaac ttttggacta ataaattaga tacaccatca ctacagtgac
    15301 atattaaaat agtattaagg ggagatttgc ttctatctat tgctgatatt aaatataaag
    15361 caagatatcc tatttcgtca tcattgactt cataattcat caactgtttg ataacagtat
    15421 tagactcttt agcagcctta taagtataag gaaatgttct ctttatatca tttaatatgg
    15481 gatttgtaat agtaaaccca tagtttattc tgtgtagaac tgatttaagg tgattagcaa
    15541 gagactttat taatattaaa tcatccttta agtttaaatt tagtatactt ccccaatgaa
    15601 cagctattgc ttcagataga ttatactctg taatttcttc atttttaaga ggttcaagag
    15661 tagtagtttt ctttattgat ttaagtaatc cttctatatg aagaaggata taacagacct
    15721 cttcatcaat aaattctacg tcaaaagctt cacttaggtt agcacataaa atttttgatt
    15781 tttcaaagta ttcatgttct aataattctc taaaaaaacc ttcagataag ttaatatatc
    15841 ttttaattga aattctttta atacatatag ctatatgtat taagaagttt atataatact
    15901 catcactaag gttacttttt tctacttgta aggtgtgtag agtgatttga gataatttct
    15961 caaaatcata gttaaatagc tccttaaata tttttgttga tggggtatct ttgcattcat
    16021 tagatttcga gaataatatt tctttaagtt cagtataact tttattaacc gtagcaagtt
    16081 caaaaattgc ttttcgaata tctttctctt ttccctctaa atatactcca ttattggttt
    16141 ttctaactag agtcacttta aagttttgca aaaaattttg aataactacc aagtctttat
    16201 gcacagtagc tctactaaca tgtagttcat tgcaaatatc acgaatccta aacttagaat
    16261 ttttaataaa taatttactt agaatatacc tttttctatc ttcaggagag tatgcatata
    16321 tacaatttga tttatcattg atatctctaa taactttaag ttttatatct tcattaccta
    16381 gaataataac ccctgaacca gtttttttat ctagggataa attaaactct aaaagccatt
    16441 catctaaaat aacaaggtca ttacgaatag ttttattact aacttttaat tcttcggcaa
    16501 tagtatctac agtaatatag tctgagctgt tgagtaataa ttcagcaata tctaataatc
    16561 ttttgttcaa tgcaaaccct cctaaatctt agttactatt tattaacctt ggaccaatct
    16621 ctttcaaaag tattggcacc atctattgta agctggttaa aagaagcttt tttaaataaa
    16681 tcatatgtta cagctgcata atcacatcca caaagagatg cttgagttaa gtggaataca
    16741 tttttaatag aagctgcaac aactttagta ttatatccat ttattgatat aaggttacat
    16801 atttctgtaa ggttttttat accatcattc ccattttcat catttctacc tataaaaggg
    16861 aataggtaat cagcacctgc atttatagct aatgatgctt gatttacatt gaaaatcaag
    16921 gtacatgcag tttttacacc tttactattt aatatgttta taagttctaa gccaacttca
    16981 gagaaattta tttttattat agtgttttta tttatattta atatcttatc acatgaatta
    17041 attaattcgt ataaattatt tccaatgact tcagcagtta atatttctgg atttaaatta
    17101 gcacatgtct caataaattc atggaagttt actttctctt taagatacat agatggatta
    17161 gcggttattc ccttaaatcc atactttaga cacttttgaa tttcatcaag attagcactg
    17221 tctatcaaat atttcataat ttaattctcc tttaagctat ttgtcataaa aaagtgtata
    17281 tactctattt ttattattaa gtcaattata caataagatt gattataaaa ttataacatg
    17341 ggtacttaat aaaatttaca taatgatatg gtaataataa aacattgatt gtctaataat
    17401 taccataagc tttagtaaat aagagttaac agtgaaggta ttgccttaaa aatcctatga
    17461 tatgtataat ttgaatatga aggcaataat ttaagggagg aaaaatatga ttaactttta
    17521 tcaaccatca agaataaatt ttggacaagg aactttaagt gaattaccta gaataatagg
    17581 aaaatatgga aagaaatgtt tgttagttac tactccaaat gtagagccat tagacaagtt
    17641 atataaaaga gttacattga atttaataga aaaaggtata gaagttgtac actttgatta
    17701 aaaaatagct acgcacactc gtgactttag tcatgagtta atagctaaaa tagtcagcat
    17761 atagggaaac ctatatgtag agataggata gaacctatcc aatactactt gaattgctgg
    17821 aaacccctaa agctaaccaa actaaaacat aaggatgaaa taaacctaag tgtgaaagtt
    17881 acgaaagtag aaaaaattgg ttagatggta taaggttaaa tcctaagtac tttaaaatgg
    17941 gcaatcagca ggtaagctcc gaataggaga aacttcaacg actattcctc ttgagggaag
    18001 tacactacaa gttatcggta gtggaagtgg gtagacctta acggataatg ccgaaggata
    18061 agatatagtc tgtgcttgca tgaaagtgta agaagttcat aagagaactg cataggtagt
    18121 agcgaactta tgtgaacgac aacctcaaaa atgataaaag
//
LOCUS       DAFAZV010000067        17715 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFAZV010000067 DAFAZV010000000
VERSION     DAFAZV010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17715
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.067"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..897
                     /locus_tag="KOU88_003511"
     CDS             <1..897
                     /locus_tag="KOU88_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBK3213343.1"
                     /translation="RINKVISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRG
                     ENPKNLVNDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLR
                     TSNICRELDGKVFDMKDYQVGITAPPFHCRCRTTTAPFFSDEEGYRAARGEDGKTYYV
                     PSSMKYNEWYEKYFKHNSILEIKNSAIIDSIKEDIKNGKYNLNIHDGKQGKHLKEHNN
                     YIEGRSYLTITKEEAQELVNKHAGNGIIKFNRSGEWDKKELIEVDKNIGVNVNNITGE
                     KTLTNKFKIHYSKTGTHIVPAL"
     gene            912..1112
                     /locus_tag="KOU88_003512"
     CDS             912..1112
                     /locus_tag="KOU88_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213344.1"
                     /translation="MKLWEYVGKNVQITCVDKQIIRGKCDGYTQALDNEPEIASISIA
                     RDGYGIEVYENEIESIENINKE"
     gene            1178..1741
                     /locus_tag="KOU88_003513"
     CDS             1178..1741
                     /locus_tag="KOU88_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBK3213345.1"
                     /translation="MDWLKELLEGIKVEDNKIDVASLQKSIEKKIKETTVTQEDYANI
                     ETQLNTANEAIKKFEGGMTKEDVENLKTTYETDKKTLEETYKKEIEEKDFNYWLGDAF
                     KSVKCRDEIALKAHLDIEALRNSKDRQKAFEEQINPLKQDKDYLFNATLEGEEPKIDT
                     ITPGQEPKINDFGFNFTGVRPHENNNK"
     gene            1753..2652
                     /locus_tag="KOU88_003514"
     CDS             1753..2652
                     /locus_tag="KOU88_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HBK3213346.1"
                     /translation="MAALNYAKEYSNVLAQAYPYTLNFGDLYATPNNGRYRWTGSKTI
                     EIPTISTTGRVDSNRDTIAVAQRNYDNAWEPKVLTNQRKWSTLVHPADINQTNYVASI
                     GNITKVYNEEQKFPEMDAYCISKIYADWTALGNTADTTVLTTTNVLEVFDKLMEKMTE
                     ARVPENGRILYVTPVVNTLIKNAKEIQRTVNIKDAGTSLNRQTTDIDTVKIIKVPSNL
                     MKTAYDFTTGWKVGAGAKQIFMSLVHPSAIITPVSYQFSKLDEPTAVTEGKYFYFEES
                     FEDVFILNKKADAIQFVVEGAGA"
     gene            2652..2885
                     /locus_tag="KOU88_003515"
     CDS             2652..2885
                     /locus_tag="KOU88_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213347.1"
                     /translation="MAQVRKLNRILTIEECKIDDFLEMGYDLIDETGKAVKYGKSLNV
                     KDLIAENNILRSKVESLEEENKQLKEKNKLTKK"
     gene            2895..3287
                     /locus_tag="KOU88_003516"
     CDS             2895..3287
                     /locus_tag="KOU88_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213348.1"
                     /translation="MENNIIDEIEKRLESFGYILKDGDKWLIGFVREKIENIIKLDCN
                     IKTMPIELKEIEVDMIVGEFLFTKKNMGQLDIESINFEAVEKSISEGDTKVDFAISQT
                     PEQRFDSLIAYLMTYGKNKILTFRCLRW"
     gene            3281..3643
                     /locus_tag="KOU88_003517"
     CDS             3281..3643
                     /locus_tag="KOU88_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213349.1"
                     /translation="MVSKTRKAIEMLYRDKCTIVEYQPIKDPVTKRTNNKEVIVLENQ
                     PCKLSYKNIVSATEGKLAKLEQTIKLFISPDISVKAGSKLIITNQNNITKEYIRSGES
                     AIYPNHQEIVLELLEDKA"
     gene            3643..4068
                     /locus_tag="KOU88_003518"
     CDS             3643..4068
                     /locus_tag="KOU88_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK3213350.1"
                     /translation="MGRGGSVNFKELKKLQRNLQRLEESQLDKFCRDCAKELAARLIG
                     KAIKRTPVDTGVLRQGWNGVAYARALPVIKAGDTYIIEIINPIKYASFIEYGHRTRNH
                     KGWVKGRYMMTISVQELRGQVDVIIEKKLINLLKKVFDA"
     gene            4061..4498
                     /locus_tag="KOU88_003519"
     CDS             4061..4498
                     /locus_tag="KOU88_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213351.1"
                     /translation="MLNNIIDGISVKLDKSFGESYTIYSEDVEQGINEPCFFIVPLNP
                     SRVSYPSGRTLKKNSFDVHYFPRSKDKSFEINEIAEMLLEELEYIEINGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            4491..4667
                     /locus_tag="KOU88_003520"
     CDS             4491..4667
                     /locus_tag="KOU88_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213352.1"
                     /translation="MSKTLSKEDNYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINSFMKGAS"
     gene            4669..5979
                     /locus_tag="KOU88_003521"
     CDS             4669..5979
                     /locus_tag="KOU88_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBK3213353.1"
                     /translation="MALGGGTFVTQNKILPGAYINFISAKRATSSLSDRGIVAMPIEL
                     DWGINEEVFQVTSDDFEKYSVKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CTIATAKYSGIRGNDLKIVVTTNIDDNTKFDVVTLLDNKKVDTQIAKVITDLQDNDYI
                     TWKKDTTLEASAGLVFTGGTNGESVTGAEYQAFLDKIESYSFNALGCLAITAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGVVSVENKVKDTGLLESSLVYWTTGAIAGC
                     DINKSNTNKKYDGEFDVDVNYTQIQLEEALKSGKFIFHKVGDEVHVLEDINTFVSFTD
                     DKNDDFSSNQSVRVLDQIANDIATLFNEKYLGKVPNDKAGRISFWNDVVKHHKELENI
                     RAIEDFKTDDVSVELGNDKKTVIVSDAVKVINAMSKLYMTVSVS"
     gene            5997..6467
                     /locus_tag="KOU88_003522"
     CDS             5997..6467
                     /locus_tag="KOU88_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBK3213354.1"
                     /translation="MFQQIKARDTISASKAECYVTIEGKRYNFMQAINLEAKMEKNKS
                     EVPILGSTTKGNKSTGSKYTGSATFHYNTSIFRELLYRYKETGEDIYFDIQVTNEDPT
                     SSAGRQTIILKDCNMDSGIIVKFDADGEYLDEDMDFTCEDWELVEKFNIINGME"
     gene            6538..6978
                     /locus_tag="KOU88_003523"
     CDS             6538..6978
                     /locus_tag="KOU88_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213355.1"
                     /translation="MSNLSAFLSQNAIKVDNVKYIASDRFLDEEGKPVEWELKVLSSE
                     EDEVLRRNCTKRVKVIGNNGKPTGQFTSEIDYNSYVAELCVASTVFPDLKDAELQNSY
                     GVMGEAQLLKTMLTAGEYVNYTVKVNEVNGFDTTFEDKVEEAKN"
     gene            7321..7482
                     /locus_tag="KOU88_003524"
     CDS             7321..7482
                     /locus_tag="KOU88_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213356.1"
                     /translation="MDNFLIGVLASLTASLIGYIVCLCIKKVKSHSVQESDLDVELKF
                     SFKFKKNKH"
     repeat_region   7764..8651
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=7764..7792
                     /rpt_unit_seq="gttttatattaactatgtggtatgtaaat"
     gene            complement(8695..8898)
                     /locus_tag="KOU88_003525"
     CDS             complement(8695..8898)
                     /locus_tag="KOU88_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008982964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213357.1"
                     /translation="MYFNIDKLLESKGRTRYWLAKEVGIAYPNMMKLANNETSSIKLD
                     LFEKLCLVLECTPNELVTLSSKE"
     gene            9142..9486
                     /locus_tag="KOU88_003526"
                     /pseudo
     CDS             9142..9486
                     /locus_tag="KOU88_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012103644.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
     gene            9568..9921
                     /locus_tag="KOU88_003527"
     CDS             9568..9921
                     /locus_tag="KOU88_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213358.1"
                     /translation="MQFLVAKTFFKKAGVDIPLEIEEKEHFYDTKQIARKLGLYTMSN
                     KPAFQAVKQIIRKLDIKEDEMKTVLETNGSWTGTVTKYSNKVTEKVKEWLKENNNPIS
                     VKGDKKNYYILYKNN"
     gene            9955..10131
                     /locus_tag="KOU88_003528"
     CDS             9955..10131
                     /locus_tag="KOU88_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213359.1"
                     /translation="MRESLLNEYNLKTDEDVEYFVKFANALYELKQNSEEKFQEYAEI
                     LRGILREQEERKNK"
     gene            10279..10497
                     /locus_tag="KOU88_003529"
     CDS             10279..10497
                     /locus_tag="KOU88_003529"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213360.1"
                     /translation="MWYVKAFRHMTTAMNIVHFILTMWYVNNITKWMFSKNKEGFRLT
                     MWYVNDKFYRFVSLVKEECRKKEKKENK"
     gene            10860..11420
                     /locus_tag="KOU88_003530"
     CDS             10860..11420
                     /locus_tag="KOU88_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012424789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK3213361.1"
                     /translation="MKKKVCFLFSILIVICLAIVGCSNSESPEESSKNNEPKKEEKKD
                     KEVVIGEKIISDKMEITINNIEFSYDVLPKVKESLYTHYPAESGKVYIDIAADIKNTQ
                     KQELNCSDLLTIEANYNDGYKYSSQTIVEDETTGFTYDNISSIDPLETKGVRFIIDCP
                     DEVKTSDKPVILSFTFDGNKYVYKMK"
     gene            11464..12033
                     /locus_tag="KOU88_003531"
     CDS             11464..12033
                     /locus_tag="KOU88_003531"
                     /inference="COORDINATES: protein motif:HMM:NF024637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HBK3213362.1"
                     /translation="MDDIVEYIFCSECGAKCLKGSKFCSECGTEIADIKMLNESIIKE
                     KEYDLKGIDLQHVMQETSFIKASSVRRLKELTGIELDDCRKILEEPYQKYYNENADML
                     EEKRKKEDDISKIRKAKEEKKEKEKIACCPACGSTSLTTHKKGFGIGKAITGATIAGG
                     IGLVAGNIGAKKVRVTCLNCGKQFWAGKK"
     gene            12104..14461
                     /locus_tag="KOU88_003532"
     CDS             12104..14461
                     /locus_tag="KOU88_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBK3213363.1"
                     /translation="MATIQTSIKIFDGMTPAFRNMTTSINTTINSLERLQGRLNNPLN
                     TGGIQTSQQSLNNIESILTRIEQSIGKADEQQRKFNDDINKGASNTDRLLGSVKKVVG
                     TYMGLKTIGGLANLSDQMTSTNARLNMINDGQLSDGGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGSAFSSTREIVSFAEQLNKKFVIAGASTQEMNSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIRSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAASAETNAQFE
                     KMPLTIGQIFASIKNNAVMIFGAIQKKIEDTVSSGGFRTFIVNVTDSLYVLGAVGCSV
                     FNGFIDLLSSPTFQGFANMMIVGISLITQGFGWLLTVLGSVINFISQGWSIIQPILIT
                     SIVLWGLYKTAVIAGALVTAIQVVWIALQTFWTNLLNGSLLTNIMMNIAAKISTDALS
                     GSMLLLITTIVMVVAAVALVIAAIFVAVAIFNHFAGTSISATGVVVGAFYFLGTCIYD
                     VFAGAWNIVMAFMEFFVNSFNICIYGVQMLFYNLANFVINSMGDVGGSFDRCATTLAN
                     VFINGVNLAIKAVNGLIELINKIPGVNIDTFGHGYTKNIDSVVGGLKNYQKTLKEPIK
                     PQDWKAPYAEIKNPFDSYKKGYEVGQNLENKLKDAFDINKIAEKAKKDLRLDDLWDKK
                     YGLGDGIGSAGLNSPLNDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINR
                     FTGVNIKIDMNNTNNINSEADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            14473..15168
                     /locus_tag="KOU88_003533"
     CDS             14473..15168
                     /locus_tag="KOU88_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK3213364.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINVGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSRELGNKVLFN
                     TNMKVSLEEYNIVEDAENGSDTKVAIKLKQYRDYSTKKLVLAPPKNETGRPSVKIEPK
                     RVDSVNATNTKTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKKVP
                     KYTIYKGQVLRLG"
     gene            15161..17116
                     /locus_tag="KOU88_003534"
     CDS             15161..17116
                     /locus_tag="KOU88_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK3213365.1"
                     /translation="MADELVLANDRDVRLIIAHWEDFYEPAVIDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRFFKNK
                     DTYVLENHTASELVKMLAKDFKLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRLTLKNVASMKLDTVMDNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TSKRDVYIAQDSAHIRSWGILQLFETVDKNMSEAEIKQKCDILLKLYNRKTKTLSLKN
                     VLGDIKVRAGCLLFITLNLGDIELQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNSNNKDEKKNGPAQSTTSKEDTEMANKINKLLKGKLSGTGNIFVKYSNAYK
                     VNPALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYNSNSAGTGVGSNEEAEKNL
                     KDVTYQIQGNNQSSSTNNSSKTDKLISIAKSKLGCNYVYGAEGPNTFDCSGFTQWCYK
                     QIGIKIPRTVATQSKAGSAVDLKDRSKWKAGDLLCRVGGGSSNHVMMYIGNGQMIHSP
                     QTGDVVKIQSVDSYRKGKAYTHVRRFI"
     gene            17130..17390
                     /locus_tag="KOU88_003535"
     CDS             17130..17390
                     /locus_tag="KOU88_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBK3213366.1"
                     /translation="MSQELLQIIKKTAIDAVETSNPMQIAFGTIESLNPLVVKIEQKL
                     SIGEIFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            17395..>17715
                     /locus_tag="KOU88_003536"
     CDS             17395..>17715
                     /locus_tag="KOU88_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBK3213367.1"
                     /translation="MIPTDNIDYDIEDVSIINFDVRQEPSKTFKLNIEKNRVDGICDD
                     VEALKQTIFLILNTERYQHLIYSWNYGVELNDLIGEPISYVIPELERRITEALIQDDR
                     IENID"
BASE COUNT         7136 a         1929 c         3362 g         5288 t
ORIGIN      
        1 agaataaata aagttatctc taaaccatgg actagtgatg gattaaattt tagtgaaagg
       61 atttggggca aacatagacc tgctttaatt aatgagttac acactaaatt gacacaatca
      121 attattagag gtgagaatcc aaaaaatcta gtcaatgact ttgctaagag atttaatgta
      181 tctaaatcac aagctaagaa tttaataatg actgaatcag ctttctttgc atcagcaagt
      241 agaaaagatt gttttaatga tttagatgta gagaaatatg agattattgc tacattagat
      301 ttaagaactt caaatatatg cagagagtta gatggaaaag tatttgatat gaaagattat
      361 caagttggaa taacagctcc accatttcat tgtcgttgta ggacaacaac agctcctttt
      421 tttagtgatg aagaaggcta tagagcagca agaggagaag atggaaaaac atattatgta
      481 ccatctagta tgaagtataa tgagtggtat gagaagtatt ttaaacataa tagtatctta
      541 gaaataaaaa atagtgctat aatagatagc ataaaagaag atattaaaaa tggtaaatat
      601 aatttaaata ttcatgatgg gaaacaagga aaacatttaa aagagcataa taattatata
      661 gaaggaagaa gctatttaac tataacaaaa gaagaagctc aagaacttgt gaataagcat
      721 gctggcaatg gaatcataaa atttaatcga agtggagaat gggataaaaa agaacttata
      781 gaagttgata agaatatagg ggtcaatgtt aataatatta cgggtgaaaa aactcttaca
      841 aataagttta agatacatta ttccaaaact ggaacacata tagtaccagc tttataagga
      901 ggaaaaataa aatgaaatta tgggaatatg tagggaaaaa tgttcaaata acttgtgtag
      961 ataagcaaat aataagagga aagtgtgatg gatatacaca agctttagat aatgaaccag
     1021 aaatagcaag tatatcaata gctagggatg gttatggaat tgaagtttat gaaaatgaaa
     1081 tagaatctat cgaaaatata aataaggaat gactaagcat gtacttaaaa ataagtagat
     1141 gcttttattt tgtaaaaaat gaaaggagaa atttaaaatg gattggttaa aagaattgct
     1201 agaaggaata aaagtagagg ataacaaaat tgatgtagct tctcttcaaa aatctataga
     1261 aaagaaaata aaggagacta cagttactca agaagattat gcaaatattg aaacacaact
     1321 taatacagct aatgaagcta ttaaaaagtt tgaaggaggt atgacaaaag aagatgtaga
     1381 gaatctaaaa acaacttatg aaactgataa gaaaactttg gaagaaacct acaaaaaaga
     1441 aattgaagaa aaagatttta attactggtt aggtgatgct tttaaatctg ttaaatgtag
     1501 agatgaaata gcattaaaag ctcatttaga tatagaagca ctaagaaata gtaaagatag
     1561 acaaaaagct tttgaagagc aaataaaccc tttgaaacag gataaagatt atttgtttaa
     1621 tgcaacacta gaaggtgaag agcctaaaat agatactata acaccagggc aagagcctaa
     1681 gataaatgat tttggtttta attttactgg ggtaagacct catgaaaata ataataaata
     1741 ggaggaaata aaatggcagc actaaattat gcaaaagaat attcaaatgt tttagcacaa
     1801 gcatatcctt atactttaaa cttcggggat ttgtatgcaa caccaaataa tggaagatat
     1861 agatggactg gttctaaaac aatagaaata ccaactatat ctacaactgg aagagtagat
     1921 tcaaacagag atacaatagc agtagctcaa agaaactatg ataatgcttg ggaacctaag
     1981 gtattaacta atcaaaggaa atggtcaaca ttggttcatc cagcagatat aaaccaaact
     2041 aattatgtgg cttcaatagg caatataaca aaagtatata atgaggaaca aaagtttcca
     2101 gagatggatg cttactgtat atctaaaata tatgctgatt ggaccgcatt aggtaataca
     2161 gcagatacaa ctgttcttac aacaacaaac gtattagaag tatttgataa gttaatggaa
     2221 aaaatgacag aagctagagt acctgaaaat ggaagaatat tgtatgttac tccagtagta
     2281 aatacactta tcaaaaatgc aaaagagata caaagaacag taaatataaa ggatgcagga
     2341 acttctctta atcgtcaaac aactgatatt gacacagtta aaataattaa agtaccatct
     2401 aatctaatga aaactgcata tgattttaca actggatgga aagtaggagc aggagctaaa
     2461 caaatcttta tgtccttagt tcacccaagt gcaataatta cacctgtttc ttatcagttc
     2521 tctaagttag acgaaccaac agcagttaca gagggaaaat acttctactt tgaagaaagt
     2581 tttgaggatg tatttatatt aaataaaaaa gctgatgcaa tacaatttgt tgttgaagga
     2641 gctggagcat aatggcacaa gtaaggaaat taaatagaat attaactata gaagaatgta
     2701 aaatagatga tttcttagag atgggatatg atttgataga tgaaactggt aaggcagtaa
     2761 agtatggcaa gtcattaaat gtaaaagatt taatagctga aaataatatt ttaaggtcaa
     2821 aagttgagtc tttagaagaa gaaaataagc agcttaaaga gaaaaataaa cttactaaaa
     2881 agtaggtgaa aattatggaa aataatataa ttgatgaaat agaaaaaaga cttgaaagtt
     2941 ttggatatat attaaaagat ggagataagt ggttaatagg ttttgtaaga gaaaaaatag
     3001 aaaatattat taaactagat tgtaatataa aaactatgcc aattgaattg aaagaaattg
     3061 aagttgatat gatagttgga gagttcttat ttaccaagaa aaatatgggt caattagata
     3121 tagaaagcat taactttgaa gctgtagaaa agtctatatc agaaggtgat acaaaggtgg
     3181 attttgctat atcacaaaca ccagaacaac gctttgatag tttaatagct tatcttatga
     3241 cttatggtaa gaataaaata ttaactttta ggtgcttaag atggtaagta aaactagaaa
     3301 agcaatagaa atgttatata gagataaatg tactatagtt gagtatcagc caattaaaga
     3361 ccctgtaaca aaacgaacta acaataaaga agtgattgta ttagaaaatc aaccatgtaa
     3421 actttcatat aaaaatatag tttctgctac agaaggaaaa ttagctaagc tagagcaaac
     3481 tattaaactc tttatatctc cagatataag cgttaaagca ggttcaaaac ttattataac
     3541 taatcaaaat aatattacaa aagaatatat aagaagtgga gaatctgcta tatacccaaa
     3601 tcatcaagaa attgtattag aattactaga ggataaagcg taatgggtag aggtggaagt
     3661 gttaatttta aagaattgaa aaagttgcaa agaaatctac aaaggttgga agaaagtcaa
     3721 ctcgataagt tttgcagaga ttgtgcaaaa gaattagcag caagattaat tggcaaagct
     3781 ataaaacgta caccagttga tacaggagtg ttacgacaag gttggaatgg tgtggcttat
     3841 gcaagggcac ttccagtcat taaagctgga gatacttaca ttatagaaat tattaacccc
     3901 atcaaatatg ccagttttat tgaatatggt catagaacta gaaatcataa aggttgggtt
     3961 aaaggtagat atatgatgac tatttcagtg caagaattaa gaggtcaagt agatgtaata
     4021 atagaaaaga aattaataaa tttattaaag aaggtatttg atgcttaata atattataga
     4081 tggaatatca gtaaaattag ataaatcatt tggagagagt tatacaattt atagtgaaga
     4141 tgtagagcaa ggtataaatg aaccttgttt ttttattgtt cctttaaatc caagcagagt
     4201 atcatatcca agtggcagga cattaaaaaa gaactctttt gatgtacatt attttcctcg
     4261 ttcaaaagat aagagttttg aaataaatga gatagctgag atgttactgg aggaattaga
     4321 gtatatagaa atcaatggag atttagttag aggcacaaat atgaattttg aaattataga
     4381 caatgttctt cacttctttg ttgattataa ctattttact ataaaaaata atgataccaa
     4441 taagatggat acagtagagt tatttggtgg tttgaagaga ggtgataatt ttgagtaaaa
     4501 cattaagcaa agaagataac tacaagttta ctaaggagca gatagttaac tctaagaagt
     4561 atgtaaatag aaaagattta ttaaatgcaa ttttaaaaga aaatgagtta tattccttct
     4621 cagaggtaga ggaaataata aatagcttta tgaaaggagc gagttaattt ggcgttaggt
     4681 ggaggaacat ttgtaacaca gaataaaata cttccaggtg cttatataaa ttttatctca
     4741 gctaagaggg caactagttc attatctgat agaggtattg tagcaatgcc aattgagctt
     4801 gattggggta ttaatgaaga agtatttcaa gtaaccagtg atgattttga gaagtattca
     4861 gtaaagtatt ttggatatga ttatacacat gaaaagttaa aaggtttgag agatttattt
     4921 aaaaacataa gattaggtta tttttataaa ttaaataaag gtgttaaagc tagttgcact
     4981 attgctactg ctaaatatag tggaataaga ggtaatgatt tgaagatagt agttacaaca
     5041 aacattgatg ataacactaa gtttgatgtt gtaacacttt tggataataa gaaagtagat
     5101 acccaaatag caaaagttat tacagactta caggacaatg actatattac ttggaagaag
     5161 gatacaacac tagaagcaag tgcagggctt gtatttactg gtggaactaa tggcgaatca
     5221 gtcacaggag cagagtatca agctttcttg gataaaatag aaagctactc atttaatgca
     5281 ctaggctgtt tggctataac agcagaaatt aaaagtttat ttgtagagtt tactaaaaga
     5341 atgagagata aagtaggagc taagtttcaa actgtactat ataaaaagaa tgatgcagat
     5401 tacgaaggtg tagtatctgt agaaaataaa gttaaagata ctgggttatt agaatctagt
     5461 ttagtttatt ggactactgg agctatagca ggatgcgata taaataaatc taatactaat
     5521 aaaaagtatg atggtgagtt tgatgttgat gtaaattaca cacaaataca acttgaagaa
     5581 gcactaaaga gtggtaaatt tatatttcat aaagttggtg atgaagttca tgtgttagag
     5641 gacataaata cttttgtatc atttacagat gataaaaatg acgatttttc aagtaaccaa
     5701 agtgttagag tacttgacca aattgctaat gatattgcaa ctttatttaa tgaaaagtat
     5761 ttaggtaaag ttccgaatga taaggcagga agaataagtt tctggaatga tgttgttaaa
     5821 caccataaag aattagagaa tataagggca atagaagatt ttaaaactga tgatgttagt
     5881 gtagagcttg gaaatgataa gaaaactgtc atagtatctg atgctgttaa ggttataaat
     5941 gctatgagta agctttatat gactgtttca gttagttaag agaggagtgt gataatatgt
     6001 ttcagcaaat aaaagcaaga gatacaataa gtgcatctaa ggcagaatgc tatgttacta
     6061 tcgagggtaa aagatataat tttatgcaag ctattaactt agaagctaag atggaaaaaa
     6121 ataaaagtga agttcctatc ttaggtagca ctacaaaagg gaataaaagt actggaagca
     6181 aatacacagg aagtgcaaca tttcactaca atacttctat atttagagag cttctttata
     6241 ggtacaaaga gactggtgaa gatatttatt ttgatataca ggtaacaaat gaagacccaa
     6301 cgagttcagc tggacgtcaa actataatac ttaaggattg caacatggac agtggaatta
     6361 tagttaaatt tgatgcagat ggtgagtatc ttgatgaaga tatggacttt acatgcgagg
     6421 attgggaatt ggttgaaaag ttcaatataa taaatggaat ggaataaaac acacatttat
     6481 aaattataga tgtgtttttt tatataaaaa attaaaataa aaggagatta ggataatatg
     6541 agtaatttaa gtgctttttt aagtcaaaat gcaataaagg ttgataatgt aaaatatata
     6601 gcaagtgata gatttttaga cgaagaagga aagccagttg aatgggaatt aaaagtttta
     6661 tcttctgagg aagatgaagt attaagaaga aattgtacca aaagagtaaa agtgattggc
     6721 aataacggga agccaacagg tcaattcaca agtgaaattg attataacag ttatgtagct
     6781 gaattatgtg tagcatctac agtatttcca gatttaaagg atgccgaact ccaaaatagt
     6841 tatggagtga tgggagaagc tcagttatta aagacaatgc ttacagcagg tgagtatgtc
     6901 aactatacag tgaaagttaa tgaggttaat ggatttgata caacatttga agataaagta
     6961 gaagaagcaa aaaactaatt aggggcggcg attttgatgc tagtatcacg cattattgta
     7021 tccaaaaatt aaagtggaaa ccaggtgatt atatgggatt agagattaat gagagagcat
     7081 tagcagccgc ctcaatactt attaagatag aggatgaaga ggaagcaatg aaagaagctg
     7141 aaagagagag aaagaggggt agaagaagat agcaaaataa aaaaataaat atagaatagg
     7201 taaaatatgt aataattata tgttataata tttttagcaa gaagatgtaa tctacaattt
     7261 atagagtgga gttcatacaa aagattatcc tcccaacgta tagaagggag gtgaatatgt
     7321 atggataatt ttttgattgg tgtattagct agtttaacag ctagtctaat cggttacata
     7381 gtttgtctat gtatcaaaaa agtaaaaagc cactctgtgc aagagagtga cttagatgtt
     7441 gagcttaaat tttcatttaa gttcaaaaaa aataaacatt aaattgttta gaacttcact
     7501 ctacttccaa atagattgta gttcttcttg tttttattat accacaaatt ggtacagata
     7561 ttcaaaaata atatatttat gatataataa aaatgtagag attttgcagt gttcgatttt
     7621 tgtaataaaa tatggcttaa caattggaat acaaggcatt gagaaggttt gataagtgtt
     7681 atcaattgca ctattacccg ctcactgcaa atttgagaaa gttatatgtg tgtaagtctt
     7741 ggaaatacac aatttatttt ggggttttat attaactatg tggtatgtaa attcattttg
     7801 actgtcaacg gtagttggtc tagtagctgg gttttatatt aactatgtgg tatgtaaatc
     7861 ccccaccact tccaccactt tgagaagttc caactggttt tatattaact atgtggtatg
     7921 taaattcaaa gccatgaggt ttttcaccta caccgctttt tgttttatat taactatgtg
     7981 gtatgtaaat actactgaca ttagttaagt aaatagtaat cttttaagtt ttatattaac
     8041 tatgtggtat gtaaatctga tttaaagaat acatttaaac tttctggcat atcgttttat
     8101 attaactatg tggtatgtaa attttcttag tgcttcatca ctctttaata aacatttagg
     8161 ttttatatta actatgtggt atgtaaatat agagctagca ataatgttaa taaagctaaa
     8221 aagacgtttt atattaacta tgtggtatgt aaattaggga attaggaaat ggctattctc
     8281 cccctatatc cgttttagat taactatatg gaatgtaaat atttgaacat ttgttacagc
     8341 attagagata ttaattgcgt tttagattaa ctatatggaa tgtaaatcca actgaataaa
     8401 caataatttt atcaatttct ttagttttag attaactata tggaatgtaa atcatcatag
     8461 tcacgtatat tttctttaaa agtcaaagtg ttttagatta actatatgga atgtaaattt
     8521 cgcaacttat gatggtgaaa tgattacatt aacaggtttt atattaacta tgtggtatgt
     8581 aaataaagca aaagatagga atgataattt taaaactcca gacttttata ttaacaatgt
     8641 ggagaaaaac taaatagaaa aaagaagcac ttacttaaat agtaggtgct tttgttattc
     8701 tttgctagat aaagtaacaa gttcattagg tgtacattca agaacaagac aaagcttttc
     8761 gaataaatct aattttatag aacttgtttc attgttagct aatttcatca tgttaggata
     8821 agctatacct acttctttag ctaaccaata tctagttcga cctttggatt caagtaattt
     8881 atcaatgtta aaatacattt tttcacctct taagtatatt atacaacaat tatataatgt
     8941 ttgcaatata taatatgcaa acaatataat tatataatgt tgacattata taatgtgtac
     9001 gatataatat acttaaggaa taaaaaataa gagccactcg cccctaccaa gtttgagtaa
     9061 ctcttattga catatactac atatgcatta attatagtat atgtcattcc ttaaaaaaaa
     9121 tcaattaagg agtgtgtttt tatgaacaat ttagtactaa ttaacaatca agaagtgcaa
     9181 gttaaggaat ttaataatca aagagtagtt acatttaaag aaattgacca agtacatgaa
     9241 agaacagaag gtacagcaaa gagaaatttc tcagagaata gaaaacattt tatagagaac
     9301 gaagatttct tttttgtaaa agcaagtgat tttgaaaagt acggaaatcg tactttagaa
     9361 attcctaatc gtggattaac tttaataact gaaacaggct atttgatgtt agtaaaatct
     9421 tttacagatg acttagcatg gaaagtacaa agacaattag taaatagtta ttttagagtt
     9481 aaagaagaaa taaaaacatt agaagcagta aatgagtcaa ttaaattaat aactccaatt
     9541 tttgaagatt taaaaattga taaaagtatg caatttcttg ttgctaaaac atttttcaaa
     9601 aaagcaggag ttgatattcc acttgaaatt gaagaaaagg aacattttta tgatacaaaa
     9661 caaattgcaa gaaagttagg actttacaca atgtctaata aaccagcatt tcaagcagtt
     9721 aaacaaatta taagaaagct tgatattaaa gaagatgaaa tgaaaacagt actagaaacc
     9781 aacggttctt ggactggtac tgtaaccaaa tattctaata aggttacaga aaaagtaaaa
     9841 gagtggttga aagaaaataa taatcccatt tctgttaaag gagacaagaa aaactattat
     9901 atattgtata aaaataatta gattttagtt ttgagtttga gggggattaa taaaatgcgt
     9961 gaaagtttac ttaatgaata taatttaaaa actgatgaag atgtagaata ctttgtaaag
    10021 tttgctaatg cgttatatga actaaaacag aatagtgaag aaaagtttca agaatatgca
    10081 gagatattaa gaggtattct tagagaacaa gaagagagaa aaaataagta aaataatata
    10141 gataaagcac ttggatatta tgatgtttca agtgctttat atggtataat ggaagtaggg
    10201 atttatatta actaagtggt atgtaaaggc tggaattaat gcgactacag tagaagaaaa
    10261 gaaaatttta tattaactat gtggtatgta aaggcatttc ggcatatgac aactgctatg
    10321 aatatagtac attttatatt aactatgtgg tatgtaaata atataacaaa gtggatgttc
    10381 tctaaaaata aagagggttt tagattaact atgtggtatg taaatgataa attttataga
    10441 tttgtaagtt tagtgaaaga agaatgtagg aaaaaagaaa agaaagagaa taaataatat
    10501 agataaagca cttggatatt gtatagtttc aagtgctttg tctgttaaaa aatggtataa
    10561 tagagataag agttatatta actatgtggt atgtaaaggt ttgagaacgc tgtataaagc
    10621 ttgtagctag ttcttgtttt atattaacta agtggtatgt aaaggttgca tcattaaata
    10681 ttttccctac aaactctttt cattttatat taactatgtg gacttaaaat taaaaataat
    10741 tcaaaaacac ttacaaatga gtaagtgttt ttttaatgaa aggaggtgat aataatgtaa
    10801 aaattttact aatatagtat aatattgtta aagaatataa tttaggggga tattatatta
    10861 tgaagaaaaa agtatgtttt ttattttcta ttcttatagt tatctgttta gctattgtag
    10921 gatgttctaa ttcagaaagt ccagaggaga gtagtaaaaa taatgaacca aaaaaagaag
    10981 aaaaaaagga taaagaagta gtcataggag agaaaattat ttcagataaa atggaaatca
    11041 ctattaataa tattgaattc tcttatgatg ttttaccaaa ggttaaggaa agtttatata
    11101 cacattatcc tgctgagtca ggcaaagtat atattgatat tgctgctgat ataaaaaata
    11161 ctcaaaaaca agagttaaat tgttcagatt tactaactat tgaagcaaat tataatgatg
    11221 ggtataaata ttcatcacaa acaatagtag aagatgaaac cacaggtttt acttatgata
    11281 atatttctag tattgaccct ttagaaacaa agggagttag atttataatc gattgccctg
    11341 atgaagtaaa aacaagtgat aagccagtaa tattaagttt tacatttgat gggaataagt
    11401 atgtttataa aatgaagtaa tttatacaaa aatgaatata ttataatacc aaggagatat
    11461 tttatggatg atatagtaga atatatattt tgtagcgagt gtggagcaaa gtgtttaaaa
    11521 ggaagcaagt tttgcagtga atgtggaacg gaaatagctg atataaaaat gttaaatgaa
    11581 agcattatta aagaaaagga atatgatttg aagggtattg atttacaaca tgtaatgcaa
    11641 gaaacaagtt ttataaaagc ttcatctgta agaagattga aagaattaac tggaatagag
    11701 ttggatgatt gtagaaaaat attagaagaa ccatatcaaa aatattataa tgaaaatgct
    11761 gatatgcttg aagaaaaaag aaaaaaagaa gatgatatat caaaaattag aaaagccaaa
    11821 gaggaaaaga aagaaaaaga aaaaatagct tgttgccctg catgtggttc aacttctttg
    11881 acaacacata aaaaaggttt tggcatagga aaagctataa caggagctac tatagcagga
    11941 ggcattggtc tcgtagcagg aaacatagga gcaaagaaag ttagagttac atgcttgaac
    12001 tgtgggaaac agttttgggc aggcaaaaaa tagatactaa aaataaaaca cttacttagg
    12061 taggtgtttt ttatgtgaaa atttaagaaa ggagagtgga aatatggcta caatacaaac
    12121 ttcaataaag attttcgacg gaatgacacc tgcttttcgt aatatgacta catctattaa
    12181 cacaacaatt aatagtttgg agagattaca aggtagattg aataatccac tcaatacagg
    12241 tggaatacag acatctcaac aaagtttgaa taacatagaa agcattctta ctagaataga
    12301 acaaagcata ggaaaagcag atgaacaaca aagaaagttt aatgatgata tcaataaagg
    12361 agcaagtaat acagatagat tattaggaag tgttaaaaag gttgttggga cttatatggg
    12421 attaaagacg ataggaggat tagcaaattt aagtgaccaa atgacgagta caaatgcccg
    12481 tttaaacatg ataaatgatg gtcaactttc tgacggagga ttgaataaaa tgattttcca
    12541 gtcggctgaa aggtcaagag catcctatct agacacagca cagatagtaa gccgtatagg
    12601 tatgaatgca gggagtgcat ttagtagtac tagagaaata gtaagctttg cagagcagct
    12661 caacaaaaaa tttgtcatag caggtgcaag cactcaagaa atgaattcag cattactaca
    12721 attaacgcaa gggctaggaa gtggtgtgct aagaggtgaa gaattaaacg ctgtatttga
    12781 gtcagcacct aacattatcc gtagtattgc ggattatttg gacgtggata taggaaaaat
    12841 tagaggaatg gcaagcgagg gaatgttgac cgcagacatt gtgaaaaatt ctttgcttgc
    12901 agcatcagca gaaacaaatg ctcaatttga aaaaatgcca cttacaatag gtcaaatctt
    12961 tgcatcaatt aagaataacg cagtaatgat atttggagcg atacaaaaaa agattgagga
    13021 tacagtttca agcggaggat ttcgaacctt catagttaat gtaacagatt cgttgtatgt
    13081 cttgggagct gttggatgta gtgtctttaa tgggtttatt gatttgctga gcagtccaac
    13141 atttcaaggt tttgcaaata tgatgattgt cggaatcagt ttaattactc aaggatttgg
    13201 gtggctatta acagtattag gaagtgttat taattttatt tcacaaggtt ggagtataat
    13261 acaacctatt ttgataacga gcatcgtttt gtggggctta tataaaacag ctgtcatagc
    13321 aggtgcttta gttacagcta ttcaggtagt gtggatagct ttacagacat tttggactaa
    13381 tttgctaaat ggttcgttat taactaatat aatgatgaat atagctgcaa aaatatcaac
    13441 agatgcacta agtggttcaa tgttactttt aattaccaca atagttatgg ttgtagcagc
    13501 agtagcctta gtaatagcag caatatttgt agcagtagca atatttaacc attttgcagg
    13561 aacaagcatt tctgcaactg gagtagttgt aggagctttc tattttctag gaacttgcat
    13621 ttatgatgta ttcgcaggag cttggaacat agtaatggca tttatggagt tctttgttaa
    13681 ctcatttaat atatgtatct atggtgtaca gatgctattc tataatcttg caaatttcgt
    13741 tataaactca atgggtgatg ttggaggttc tttcgataga tgtgcaacaa cacttgcaaa
    13801 tgtatttata aatggagtaa atttagcaat aaaagcggta aatgggttaa ttgaattaat
    13861 taataaaata cccggagtaa acatagatac atttggtcat ggttatacaa aaaatataga
    13921 ctctgttgtt ggaggtttaa aaaactacca aaaaacatta aaagagccta ttaaaccaca
    13981 ggactggaaa gctccatatg cagaaatcaa aaatccattt gactcttaca aaaaagggta
    14041 tgaagtaggt caaaatttag aaaataaatt aaaagatgct tttgacatta acaagatagc
    14101 agaaaaggca aaaaaagact taagattaga cgatttatgg gataaaaaat acggacttgg
    14161 tgatggaata ggctcagcag gattaaattc tccactgaac gatgcagcaa aaggagcaaa
    14221 agacactgcg ggaaatacag ctaaaatggc taaaacaatg gataaaagcc aagaagactt
    14281 aaaatatctt agagacattg cagagcaaga aacaataaac cgattcacag gagtcaacat
    14341 taaaattgac atgaacaata caaacaacat aaatagtgag gcagatgtag atggaatagt
    14401 aaatgtacta acagaaaaat taaacgacgc tatggttgta tcagctgagg gaatagtcta
    14461 ggaggtgttt gaatggctta tgatttttac ctagatggag tacaactacc aatcgcacca
    14521 cccaagcttg aagtcaaagt gacaaataaa aacaagacag ttgatttaat aaatgttgga
    14581 gaagtaaaca tattaaaaaa agaaggatta tctgaaataa gttttgaagc agaatttaca
    14641 cataataaat taccttttta tcgtggaact tttagggatg ttcaattctt tttaagtaaa
    14701 ctagaattac taaaaactga ttgtaagcca tttcaattta ttgtatcgag ggaattaggt
    14761 aataaagtac tatttaatac taatatgaaa gtatcattag aggaatataa catagtagaa
    14821 gatgcagaaa atggctcaga tacaaaagtt gcaataaagt taaagcaata tagagattac
    14881 tcaactaaaa agttagttct tgcccctcct aaaaatgaga ctggtagacc aagcgtaaag
    14941 atagagccaa aacgagttga ttcagtcaat gccacaaaca ctaaaactaa aacatataca
    15001 gtaaaagcag gggatagcct ttggtcaatt tgtcagaagc aacttggtaa tggttcatta
    15061 tataagaaag tatatgagtt aaataaaaca atgatggata aggctaacaa gggtaaaaaa
    15121 gtacctaaat ataccatcta taaagggcag gtgttgaggc ttggctgatg aattagtgtt
    15181 agcaaatgat agagatgtaa gattaatcat agcacattgg gaagatttct atgaacctgc
    15241 tgtcattgat ggtatcacat gggaaataga gagacgagga acaccatcta aacttgaatt
    15301 tacaatagtc atggatgata tattagagtt ttgtgaaggt aactctgtaa ggctgtatta
    15361 taaaggaata ggtatattct atggatatat atttcagaaa aagagagata aagaaaatca
    15421 tatcaagata gttgcctatg accaattaag attttttaaa aataaagata cttatgttct
    15481 tgagaaccat actgcaagtg aacttgtaaa gatgttagct aaagatttta aattaaaata
    15541 caatgtcata gaagatacaa aatataaaat atcgagagtt gaagaaaata aaacactctt
    15601 tgatatggtc ttaactgcac tagatgatac tctaagagag aaaaaggaaa tgtatgtact
    15661 ctatgatgat tttggaagat taacattaaa gaatgttgct tctatgaaac ttgatacggt
    15721 tatggacaat gatgtaattg aggactttga ctataattca tcaatagata gtgataccta
    15781 cacaaagatt aaacttgtga gagataatga ggagacaagt aaaagagatg tgtatattgc
    15841 ccaagattca gcacatataa ggagttgggg tattctgcaa ctatttgaaa cagtagataa
    15901 gaacatgagt gaagcagaga taaaacaaaa atgtgatata cttttaaaat tatataatag
    15961 aaaaactaaa acactaagtt taaaaaatgt gcttggtgat attaaagtga gagctggttg
    16021 tttacttttt ataacattaa atctaggaga tattgaattg caaaattata tgttagttga
    16081 gaaagtaaaa catacatttg aaaataattc acatttcatg gatttgactc ttgttgatgg
    16141 agatgaattt gcttcttatt cttcttcaag ctacagtagt ggaaatagta ataataaaga
    16201 tgaaaagaaa aatggtcctg cacaaagtac tacaagtaaa gaagatactg aaatggctaa
    16261 taaaattaat aaactactta aaggtaaatt atcaggaaca ggaaatatat ttgttaaata
    16321 ttcaaatgct tataaagtta atccagcatt aatggcggct atatctatgc acgaatcagc
    16381 tagagggact tcaaatattg caaatactaa aaataatttc tttggaatga aaaaaaatgg
    16441 agattacatg agtttttcta gtgtagacga aggaataaaa agaggtataa gtaatttatc
    16501 aagaaactat atccatatag gacgaaaaac tttagaaagc atcagaaata aatattcttc
    16561 tagttcagac aaagaatggg taaaatgtgt aggtgcattt tataagcaaa taacaggaag
    16621 tacttataat tctaatagtg caggtacagg agttggaagt aacgaagaag cagaaaagaa
    16681 tttaaaagat gtaacttatc aaattcaagg caacaaccaa agcagtagta caaataatag
    16741 ctctaaaaca gataaattaa ttagtatagc aaaaagtaaa ctgggttgta attatgtgta
    16801 tggagcagaa ggtcctaata cttttgattg ttctggattc actcaatggt gttataaaca
    16861 aataggtata aaaattccta ggactgttgc aacgcaaagt aaggcaggca gtgcagtaga
    16921 tttaaaagat agaagcaagt ggaaagcagg agacttatta tgtagagttg gtggaggtag
    16981 tagtaatcac gtaatgatgt atattggaaa tggtcaaatg attcattcac cacagactgg
    17041 tgatgtagta aaaatacaat cagttgattc atatagaaaa ggaaaagcat atacacatgt
    17101 gagaagattt atataagtga ggtgataaag tgtcacaaga attattgcaa ataattaaga
    17161 agactgcaat agatgcagta gaaacaagca atccaatgca gattgcattt ggaactatag
    17221 aaagtcttaa tccattagta gttaagatag aacaaaaact atctattggt gaaatttttc
    17281 taatacaaac agatacattt aaaagatata cagataaaaa gataggagat aagttagttt
    17341 taattcgtat gcaaggaggg caacaatact tgattttaga taggatgtga tgaagtgata
    17401 ccaacagata acattgacta tgatattgaa gatgtctcaa taattaattt tgatgttaga
    17461 caagaaccaa gtaagacgtt taaattgaat atagagaaaa atagagtaga tggtatttgt
    17521 gatgatgtag aagcattaaa acaaaccatc tttttgattt taaacacaga gagataccaa
    17581 catctaatct atagttggaa ttatggagtc gagttgaacg accttattgg agaacctatt
    17641 tcatatgtaa tacccgaact tgaaagaagg ataacagaag cactaattca agatgatagg
    17701 attgaaaata tagat
//
LOCUS       DAFAZV010000068        17293 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFAZV010000068 DAFAZV010000000
VERSION     DAFAZV010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17293
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.068"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(200..1450)
                     /locus_tag="KOU88_003537"
     CDS             complement(200..1450)
                     /locus_tag="KOU88_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1015 domain-containing protein"
                     /protein_id="HBK3213368.1"
                     /translation="MATIKPFKAIRPNKYIVDKVAALPYDVMNSKEARRIAEGNPYSF
                     LHIDKSEIDLDENIDLYDEKVYLKARENLDEFRKQEILVKDDKECIYIYKQIMDGRAQ
                     VGIVACISVDESLNGTIKKHEYTRPEKEIDRTKHIKYCDANTGTILVTYKHQRVIDDI
                     INDFMDNNEPLYDFITDDKIEHTVWKIDNDDIIDNLVDKFEKLDYLYIADGHHRTASA
                     ENVAKEMRAKNPNYTGKEEFNYFIAMIAPDENLMVLDYNRVIKDLNGLSEEEFINKIK
                     ENFELEEIEGKEKYKPDKKGTFGMYLGDKWYKMKANKNLLEIEDPVDSLDISILQDYV
                     IDAILGIDNPRVDKRIDFIGGIRGLEELEKRVNEDMKVAFAMYPTSIEDLIRVADANK
                     IMPAKSTWFEPKVRCGLFLHEINE"
     gene            complement(1482..2423)
                     /locus_tag="KOU88_003538"
     CDS             complement(1482..2423)
                     /locus_tag="KOU88_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HBK3213369.1"
                     /translation="MYNILVTDGIEKEAARKLRELDFNVIEQFYEKDVLGDKLKDVDV
                     LVVRSATKVTKDVIDKALEGKKLKLIVRGGVGLDNIDVKYAQANGIKVMNTPNASSIS
                     VAELTIGQLFVLARFINTANVTMRDGKWEKKKYKGTEINGKTLGLIGFGRIAKEVAKR
                     AELLGMNVIYTDIMGEAQGFNNYKFCDMEEVLENADFLSLHIPFDKNKGAVITEKEIN
                     KMKKGAYLINCARGGLVDEKDLLKALDEGKLSAAAIDVYEQEPTLNLDLVNHPRVSPT
                     PHIGASTVEAQERIGDEIVNVIQDFFLDFNNLIGVAL"
     gene            complement(2663..3739)
                     /locus_tag="KOU88_003539"
     CDS             complement(2663..3739)
                     /locus_tag="KOU88_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
                     /protein_id="HBK3213370.1"
                     /translation="MSKKLFIPGPIDVKEEVLQKMATPMIGHRGKDASMLQKSISEKM
                     QKLFYTNNTILLSTSSGTGLMEGSIRSCTSKKAAVFSCGSFGDRWYKMAVANNVPADI
                     FKVELGEATTPEMVDKVLSTGEYDLITVTHNETSTGIRNPIEEIGEVVKKYEDVIYCV
                     DTVSSAGGIKVEVDKIGIDICITSVQKALGLPPGMSICTFSQKAIDRAKQVPFRGVYL
                     DLLAMYEYLIKKNYQYPSTPSLSHMFALDFQLDNILDEGLDNRFNRHEDMANLVRNWA
                     KKHFQIFTNENHLSNTLTVIENTQGISVSNLNSKLQERGFQIANGYGDLKEKTFRISH
                     MGDYTVEDVQELLDNIDDILGFNK"
     gene            complement(4112..4627)
                     /locus_tag="KOU88_003540"
     CDS             complement(4112..4627)
                     /locus_tag="KOU88_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HBK3213371.1"
                     /translation="MDFLAKYKVLKKQNSSKSCLVCGTQNELGLKADFYELENGELVS
                     ICNTKDWHQSYPGRVHGGMSAAILDETIGRAVSINDDQIWGVTVSLELKYKKPVPTDA
                     TIKVVGRITKENRKLFEGTGEIILPNGDIAVTATGKYMKMPIGQIAEGDFSNEEWFFE
                     ESKEKVEYIEL"
     gene            complement(4990..6060)
                     /gene="leuB"
                     /locus_tag="KOU88_003541"
     CDS             complement(4990..6060)
                     /gene="leuB"
                     /locus_tag="KOU88_003541"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBK3213372.1"
                     /translation="MNCNIAVIKGDGVGPEIIDEGIKVLNKICCKFNHRFDCEYVLAG
                     GCAIDETGEPLPNKTVETCRKNEAVLLGAVGGPKWDKCKGDKRPESGLLKLRESLGLF
                     ANLRPATMYESIKEASPLRTDIVEKGIDFVVVRELTGGIYFGERGRKIIDGIENAYDV
                     EIYNENEIRRIGKRAFEIARNRNKKLISVDKANVLESSRLWRSIMEDLAKEFEDVELS
                     HMYVDNAAMQVVKDPSQFDVIVTNNIFGDIISDEASMITGSIGMLPSASLREDSFGMY
                     EPIHGSAPDIAGKDIVNPIATILSVSMMLRHSFNLEEEAKCIEDAVQSVLNKGYRTID
                     IYNGVGNVVGTREMGELIVNEI"
     gene            complement(6067..6558)
                     /gene="leuD"
                     /locus_tag="KOU88_003542"
     CDS             complement(6067..6558)
                     /gene="leuD"
                     /locus_tag="KOU88_003542"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBK3213373.1"
                     /translation="MIANGSVFKFGDNIDTDVIIPARYLNIADYKELATHCMEDIDDK
                     FISKVKKGDIIVATKNFGCGSSREHAPIVIKESGVSCVIASTFARIFFRNSINIGLPI
                     LECEEAANNIDEGDNIEVDFSTGVIKNITKGKEYKAEPFPEFMQNIILNEGLINSIKA
                     NRG"
     gene            complement(6573..7850)
                     /gene="leuC"
                     /locus_tag="KOU88_003543"
     CDS             complement(6573..7850)
                     /gene="leuC"
                     /locus_tag="KOU88_003543"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBK3213374.1"
                     /translation="MGMTMTQKILAKHAKLNEVKKGQLIEADLDVVLGNDITSPVAIR
                     EFEKLGIEDVYDKTKVVMVLDHFTPNKDIKSAEQCKFTRSFAKSKGVVNFFDVGDMGI
                     EHVLLPEKGIVTAGDVIIGADSHTCTYGALGAFSTGVGSTDMGAGMATGKCWFKVPGA
                     IKFVLKNKPNKWISGKDIILHIIGEIGVDGALYKSMEFCGDGVEYLSMDDRFTICNMA
                     IEAGAKNGIFPVDDKTMEYINSHKCSTMTKDVNIYEADEDAVYDEVYEIDLAELKETV
                     AFPHLPENTRTVDEIDKDIKIDQVVIGSCTNGRISDLEVVAEIMKGKKVADGVRVMIF
                     PGTQKVYLEAIEKGYITTFIEAGAAVSTPTCGPCLGGHMGILAAGEKSISTTNRNFVG
                     RMGHVDSEVYLASPAVAAASAITGKISKPSEII"
     gene            complement(7807..9549)
                     /gene="leuA"
                     /locus_tag="KOU88_003544"
     CDS             complement(7807..9549)
                     /gene="leuA"
                     /locus_tag="KOU88_003544"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBK3213375.1"
                     /translation="MKCGKYKKYDKMQIVNRKWPDNEIFKAPIWCSVDLRDGNQSLPT
                     PMSVNEKVRMFKMLIDTGFKEIEVGFPSASNTEYTFLRKLIDENMIPDDVTIQVLTQS
                     RAHLIEKTFESIRGCKKAIIHLYNSTSVLQRDVVFNMSKQEIIDIAVEGAKLFNEEVK
                     KYPETEFTFEYSPESFTGTEMDYALEICEAVIDVWKPTPQKKVIINLPSTVEMATPNV
                     YADQIEWFCKNISCRDSIILSLHTHNDRGTCTAASELGLLAGADRLEGTLFGNGERTG
                     NMDIVNVGLNLYTQGIDPELDFSNIDKIIGIYEDCTKLMVHDRHPYAGNLVHCAFSGS
                     HQDAIRKGMIAMKNRDNDYWEVPYLPIDPHDIGREYKEIIRINSQSGKGGAVYIMETD
                     YGFMIPKNMHSDFGNVVKMESDRIGEELSSEAIFNLFKKEYIEVESPYKVKKYKIKSM
                     DELNYENDDSNDTNMIEMTARISYMGNEQRIVGIGNGPVDSFNNALKQCGMKDYKFRY
                     YWEHALEEGSHSRGVAYVGIEHNNEVYFGVSISENINTAAINALMNAINKSYIEEEIK
                     NGDDYDAENISQTC"
     misc_binding    complement(9673..9919)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(10067..10513)
                     /locus_tag="KOU88_003545"
     CDS             complement(10067..10513)
                     /locus_tag="KOU88_003545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213376.1"
                     /translation="MSKNKFIYMNYYDNGYFKKGMTIYMVLALIILATIFIYSTTILY
                     ILCIITAVFLFKQGRDFSNKYEGKVYITLDNHSILINNQCIFSIKSKQSQKFNYKIIE
                     KIEVVKNILNIYTDESNYKIRLRALSLEDEKKLLNIIDEKMKKFKA"
     gene            complement(10534..11253)
                     /locus_tag="KOU88_003546"
     CDS             complement(10534..11253)
                     /locus_tag="KOU88_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="HBK3213377.1"
                     /translation="MKKSIMDVHCHTLISGHAHSTFKENVEEASKKNIKYLGISDHGP
                     NMPGGPHPFYFYNLHLLPREVQGVKILRGIEGNIMDYNGNLDVQEDMLKHLDYIIASL
                     HRPCIASGTKEKNTNAILKVMDKPKVKIIGHPDDSRYPLDYEPIVKKAKDKNILLEIN
                     NSSLSSNSHRTGTWENVSHMLTLCKTYGARVILGTDSHICYSIGEFENAEKVLEAVDF
                     PDELVINYHEDEIIEFFDINF"
     gene            complement(11371..12645)
                     /locus_tag="KOU88_003547"
     CDS             complement(11371..12645)
                     /locus_tag="KOU88_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBK3213378.1"
                     /translation="MFIMENDLTMQELLDQQEQVFSKVKVGELTTGKITAVRNDEVQL
                     GLDYGFDGIIPISELNIEKNQYIEDIYHIGDEITAVITKVSQKDGTITLSKLQLDKRN
                     DFAKLQKAYDEHRIITVNVEKNIDKGVFANYNTYTFFIPISQLDTKFITDTSKFVGLN
                     LEVYIKELDVRKNRLVASHRDVLQERINKEREERRAQIKAEKEAERARIKQEREEEKA
                     RIKAAKEDLFNSLEVGQKRDGKVTKIMPYGAFVDIGGIEGLAHINNLAWTRVESVEDV
                     VSEGQEVEVYVLDVNKETKKIALALKDINNDPWDLIAKEVQIDDVVNAKVLRIIEKGA
                     FVQIKEGVDAYLPISELSDTRVAKVTNVVNIGDEVKVKILDFKPKTKRMLVSIKEATR
                     EPEEDITEYLEVEESLGSIGELFKDKFKDLEV"
     gene            complement(12845..14212)
                     /locus_tag="KOU88_003548"
     CDS             complement(12845..14212)
                     /locus_tag="KOU88_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3213379.1"
                     /translation="MENSNTNLGSESVGKLLFKLATPAIIAQIVNVLYNIVDRIFIGR
                     MENGEVAMAGVGVAFPIIIIITACSYLIGMGGGPLAAIKMGEQNNDEAEKIMSNSFSV
                     LVILAILLTIGFKIGKEPLLWMFGASESTIGYSMDYLNIYLIGTVFVQISMGMNTFIN
                     TQGFATTGMMTVAIGALINIILDPIFIFGFNMGVKGAALATIIAQGVSAIWVLMFLFG
                     KKSILKIKKKYMIPKASIILPVLGLGISPFIMQSTESLVLIALNSKLQMYGGDLAVGS
                     MAIMSSIMQILMLPNMGVTQGAQPIISYNYGSGQLDRVKKTFKLCLLSCFTYSTILWL
                     LLMIFPAFFVSIFNKNPQLLSMTSWSIKIYFAGAFMFGIQIACQQTFLALGKATISLV
                     LALLRKIVLLIPLIFILPTFFNEKLFAVILAEPVADITAATITAISFFIFYKCFLSKP
                     KAIKE"
     gene            complement(14462..14926)
                     /locus_tag="KOU88_003549"
     CDS             complement(14462..14926)
                     /locus_tag="KOU88_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBK3213380.1"
                     /translation="MSLRIGGNSLGYLHILILSMVPVTELRGAIPIGIAMGLNPIWVY
                     VFSVIGSTLVSIPLILTFRHVLQFLRGKKLFKGIADVIDRKINSRMKKLKSVSIIGII
                     LFVGIPLPTTGTWTASAIASILKMRIKDAFMGVFLGNLLSGVIVSALSLHII"
     gene            complement(14931..15560)
                     /locus_tag="KOU88_003550"
     CDS             complement(14931..15560)
                     /locus_tag="KOU88_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family hydrolase"
                     /protein_id="HBK3213381.1"
                     /translation="MKKSVLLLDVDYTVINTDSMIDFFIYSLKNKTFKTIIKLPYIIF
                     ILFMYLIRMIPLKKAKEAIFYPIVDFSEEDLKKFFDDCIMKKINESMKKVIYKNKEED
                     NVIIMITASPYAYMKYFKYYGLADEVIGTEFFYENSRYKNQFIGENCKGIEKLKRIKA
                     VLGKLGIEIDYENSYAYSDSKSDLPMLSLTKNAFLVSKKDGEVIEQINS"
     gene            complement(15594..16481)
                     /locus_tag="KOU88_003551"
     CDS             complement(15594..16481)
                     /locus_tag="KOU88_003551"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBK3213382.1"
                     /translation="MKQTNTSIRLLTKISDYIKLMRIKQYIKNFFVFSAIIFSNNILN
                     INLFLNTFIAFVCFCLMSSSVYALNDAIDMDKDKKHPKKCNRPVASGRISKKSANILF
                     VVLALISVCLSTVVSFNLSIILSLYLINNILYSLKLKNIILLDVFSISLGFILRVYAG
                     CVAISVSLSNWIILCTFFLSLYLALGKRKKEIETLRDDAVEHRKILEDYDIENLNQMM
                     IVILSSTIVCYALYSTSNPEKPHMIFTTIFVVYGVLRYNYIINTTNENNPTDIVLKDN
                     ALKINVILWIITCLIILIF"
     gene            complement(16510..>17293)
                     /locus_tag="KOU88_003552"
     CDS             complement(16510..>17293)
                     /locus_tag="KOU88_003552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213383.1"
                     /translation="QLFITLNVERFIYSQFSLIFFIVIANKMKGKNSYLVELAAIPLF
                     GITISNIYLYFFNMIFEFKLKIGKMLKHLITFILMAYICVVSTKSYESFMNLGNVIQY
                     DTKFISGEPILEKIAMIIERLLYSVFYFPGASIKKGLFLQNGEVATIPVILTLLALCF
                     CVLSVIENSEKRVPKLCMGIIIFNLTLHGIVGYNLVNSSIMAINFSFAVIILLAYFTK
                     ALRKNEKNMYNIFLSLLLVTIVISNVNGFIEILNIGIKSYPV"
BASE COUNT         5522 a         3193 c         1777 g         6801 t
ORIGIN      
        1 tacaaataca attatatgaa ttttcatcct caattatagc atagaatatg actatctata
       61 tcctaaaatt atccatttct aaaaaaaagg taactattat taagaatatc aacttataga
      121 atttatattc cacatacgat tttcaatcaa aaaaacaagg gctaaaaagt gaattgtgca
      181 ctttttagcc ctttattaat tattcattta tttcatgtaa gaatagacca catcttactt
      241 taggttcaaa ccatgttgac ttagctggca ttatcttatt tgcatctgct actcttatta
      301 aatcttcaat actagtagga tacattgcaa atgctacttt catatcttca ttaactcttt
      361 tttctaattc ttcaagacct ctaattccac cgataaaatc aattctttta tctactctag
      421 gattatcaat tcctaaaata gcatcaataa catagtcttg taatatagaa atgtctaatg
      481 agtcaacagg gtcttctatt tctaataaat ttttatttgc tttcatttta taccacttat
      541 cacctaggta cattccgaaa gttccttttt tgtcaggttt atatttttct tttccttcta
      601 tttcttctag ttcaaaattt tcttttattt tatttataaa ttcttcctcg cttaaaccat
      661 ttaagtcttt gataacccta ttataatcca aaaccattaa attctcatct ggtgcaatca
      721 ttgctatgaa gtaattaaat tcttcttttc cagtataatt tggattttta gctctcattt
      781 ctttggctac attttctgct gaagctgtcc tatgatgacc atctgcaatg tatagataat
      841 ctaatttttc aaatttatct actaggttat ctattatatc atcattatca atcttccata
      901 ctgtatgctc tatcttgtca tctgttatga aatcatataa aggttcatta ttatccataa
      961 aatcattgat tatatcatct atcacccttt gatgtttgta agttacaagt atagttcccg
     1021 tattagcatc acagtatttt atgtgtttag ttctatcaat ttccttttct ggtcgagtgt
     1081 actcatgttt ttttattgtt ccattcaagc tttcatcaac tgatatacat gctactatac
     1141 caacttgagc tctaccatcc atgatttgtt tatatatata tatacactct ttgtcatctt
     1201 ttactagaat ttcttgtttt cgaaactcat ctaaattttc tcgcgctttt aaataaactt
     1261 tttcatcata taaatctata ttttcatcta aatcaatttc tgatttatct atatgcaaaa
     1321 atgaatatgg attcccttct gcaattcttc tagcttcttt actattcata acatcgtaag
     1381 gaagtgctgc tactttatct actatatatt tatttggtct aatcgcctta aatggtttaa
     1441 tcgttgccat tactaatttc ctcctaatta tacaaaatat tttataatgc tacccctatt
     1501 agattgttga agtcaagaaa gaaatcttga atcacattta ctatttcgtc tcctattctt
     1561 tcttgagctt ctactgtaga tgccccaata tgaggtgtag gagaaactct tggatgattt
     1621 actaagtcta aatttaatgt aggttcttgt tcataaacat ctatagcagc tgctgataat
     1681 ttaccttcat ctaatgcttt tagtaaatct ttttcatcaa ctaaaccgcc tcttgcacag
     1741 tttattaaat aagccccttt cttcatctta tttatttctt tttcagttat tactgccccc
     1801 ttattcttat caaatggtat gtgtaaagat aagaaatctg cattttctaa aacttcttcc
     1861 atatcacaga atttataatt gttaaagcct tgcgcctcac ccattatgtc agtatatata
     1921 acattcatac ctaataattc tgctctcttt gcaacttctt ttgcaattct tccaaaacct
     1981 ataagtccaa gtgtctttcc attaatttct gtacctttat actttttctt ctcccatttt
     2041 ccatctctca tagttacatt tgcagtattt atgaatcttg caagaacaaa taattgacct
     2101 attgtaagct ctgcaacaga tatactgctt gcatttggag tattcataac ttttatgcca
     2161 ttagcttgag catatttaac atctatatta tccagaccta ctccacctct tactatcaac
     2221 ttcaactttt taccctctaa tgctttatct attacatctt tagtaacttt agtagctgaa
     2281 cgtactacaa gtacatcaac atctttaagt ttatctccta aaacatcttt ttcataaaac
     2341 tgctctatca cattaaaatc taactctctc aattttctcg ctgcttcttt ctctattcca
     2401 tcagtaacta atatattata cataacaaac tcctccaatt tttattcact taatttttcc
     2461 aatttttatt ttttaaagta ttttcatcaa taaaaaactt tacttaattt aactttctgt
     2521 ttatataatt ttcaaaatat ttttttatta aagtcatatc aaatttttct attgtttgtt
     2581 aaaaatttaa tatgtaattt ttataaaata ttatttatta tatattctaa atttatctta
     2641 aaacatacat atttttacaa tattatttat taaaacctaa tatatcatca atattatcta
     2701 ataattcttg tacatcttcg acagtatagt cacccatatg tgaaattcta aaagtttttt
     2761 cttttaaatc tccatagcca tttgctattt ggaatcctcg ttcttgtaat tttgaattta
     2821 aatttgatac actaatacct tgagtatttt ctataacagt aagtgtattg gataagtgat
     2881 tttcattggt aaaaatttgg aagtgttttt tagcccagtt tctaactaag tttgccatgt
     2941 cttcatgtct gttgaatctg ttatctaggc cttcatctaa tatattatct aattggaaat
     3001 ctaaagcgaa catgtgagaa agagatggtg ttgaagggta ttggtagttt ttcttgatta
     3061 agtattcata cattgctaac aaatcaagat atactcctct aaaaggtact tgcttagctc
     3121 tatcgattgc tttttgagaa aatgtgcaaa tagacattcc tggtggtaat cccagtgctt
     3181 tttgtactga tgttatacaa atatctattc caatcttatc aacctcgact tttattccac
     3241 cggctgaact tacagtatct acacagtaga ttacatcctc atacttttta acaacttctc
     3301 caatttcttc tattggattt cttattccag ttgaagtttc attgtgagtt acagttatta
     3361 aatcgtattc tccggtagaa agcaccttat caaccatttc tggcgttgtt gcctctccta
     3421 attcaacttt aaatatatcc gctgggacat tattagccac tgccattttg taccatctat
     3481 caccaaagga tccacaggaa aatactgctg cctttttgga tgtacaggaa cgaatggagc
     3541 cttccattaa accagttccg gatgacgtgg ataaaagtat cgtgttgttt gtatagaata
     3601 gtttttgcat cttttcactt atactctttt ggagcataga tgcatctttt cctctatgtc
     3661 ctatcattgg tgtagccatc ttttgcaaga cttcttcttt aacatcaata ggaccaggaa
     3721 taaataattt cttactcatt ataattcccc cctttttagt ttgtaatatg gatagcgttt
     3781 ttactgtcct tatttttaat aactataata tcaagctgaa ttaactatgt caacataaaa
     3841 tttatttttt atatataatt tattttatat attttatgaa aacattcatt ttctaccttt
     3901 tcataagtct gaattttctg aattattctc tcaaaaaaaa tatacttttt atctatataa
     3961 attaattttt ttagtatgta aattttacgc tattacgata aatcttttta gtataactaa
     4021 tttattttta tcttgtattt ttattgtatt tttgaatttt attttttcta aatataaaat
     4081 ttatgtttta aaatataaaa tttttattta atcaaagttc aatatattcc actttttctt
     4141 tcgattcttc aaaaaaccat tcttcattag aaaaatcacc ttctgcaatt tgtccaatag
     4201 gcattttcat atactttcca gttgctgtca ctgctatatc tccatttggt agaattattt
     4261 ctcctgtacc ttcaaataat tttctgtttt ctttagttat tcttccaaca acttttatag
     4321 tagcatctgt tggtactggt ttcttatatt tcaactctaa agatactgtt actccccata
     4381 tttggtcatc atttatactt acagctcttc caatagtctc atccaatatt gcagcagaca
     4441 tacctccatg aactctccca ggataacttt gatgccaatc ctttgtatta caaattgata
     4501 caagctctcc attttcaagt tcataaaaat ctgctttaag tcctagctca ttttgtgttc
     4561 cacaaactaa acaagattta ctactatttt gcttcttcaa aactttatac tttgccaaaa
     4621 aatccatctc ctaaccgaca ttagtagtcg cttaatatta aataattcta aaatatatta
     4681 tataatatta ataaaatccc tgcaaacttc taataataaa aataggctac ttcaatatga
     4741 taagtttaat ttaaagtatt attttccaaa aaataacttt atcaaaatag aaactcaaag
     4801 tagatataaa cctctttttc gttattaaaa tagtaaaaat atatttgact taatataaaa
     4861 aagagtgtct cattaactaa taaagtttat tttgagacac ccctcataaa acaaattata
     4921 ctacaataga tttttactaa ttctacaagt tatatattta aattatatta ttcaaattaa
     4981 actataattc taaatttcat ttactattaa ttcgcccatt tcccttgttc ctacaacatt
     5041 tcccacacca ttatagatat caatagttct ataaccttta ttgagtacac tttgtacagc
     5101 atcttcaata cacttagctt cttcttctaa gttaaaacta tgtcttaaca tcatgcttac
     5161 agatagaata gtcgcaattg gatttacaat atcttttcca gctatatcag gtgcacttcc
     5221 atgtattggt tcatacatac caaaactatc ttctctaagt gatgctgatg gtaacatacc
     5281 tatagaaccc gtaatcatag atgcttcatc agatattata tctccaaata tattattagt
     5341 cactattaca tcaaattggc tagggtcttt tacaacttgc atagcagcat tatcaacata
     5401 catatgtgac agttctacat cttcaaactc tttagctaag tcttccatta tacttctcca
     5461 aagtcttgaa ctctcaagca catttgcctt atctacactt ataagttttt tatttctatt
     5521 tctggctatt tcaaaagctc tcttaccaat tcttcttatt tcattttcgt tatatatttc
     5581 tacatcataa gcattttcga taccatcaat gatttttctt ccacgttctc caaaataaat
     5641 gccccctgtt aattccctta caacaacaaa atcaatgcct ttctcaacta tatccgttct
     5701 aagtggtgaa gcttctttta tactttcata cattgtagct ggtcttaaat ttgcaaataa
     5761 acccaatgac tctcttaatt ttaaaagacc agactctggt cttttatctc ccttacattt
     5821 atcccacttt ggtcctccaa cagcaccaag caatacagct tcgttttttc gacaagtttc
     5881 aacagtttta ttaggtagag gttctccagt ttcatcaatc gcgcatcctc cagctaatac
     5941 atattcacaa tcgaatctat gattaaattt acaacaaatt ttatttagaa cctttatacc
     6001 ttcatctata atttccggtc caacaccatc accttttatg actgctatat tacaattcat
     6061 acttcactac cccctatttg cttttattga gttaattaag ccttcattta atataatatt
     6121 ttgcataaac tcaggaaatg gttctgcttt atattctttt ccttttgtta tattttttat
     6181 cacacctgta gaaaaatcta cttctatatt atccccttca tctatgttat tggcagcttc
     6241 ttcacattca agtataggaa gccctatatt tatagagttt ctaaaaaata ttctagcaaa
     6301 agtagaagca atcacacagg atactccact ttcttttatt acaattggtg catgttctct
     6361 tgatgaacca caaccaaagt ttttagttgc aactataata tctccttttt ttaccttaga
     6421 aataaattta tcatcaatat cctccataca atgcgttgct agttctttat aatcagctat
     6481 atttaaatat ctagctggta ttattacatc tgtatctata ttgtcaccga atttaaaaac
     6541 acttccattg gcaatcataa attttacctc ccttaaatta tttctgatgg ttttgatatt
     6601 tttccagtta tagctgatgc tgctgctaca gctgggcttg caagatacac ctctgaatca
     6661 acatgcccca ttcttcctac gaaattccta tttgttgttg aaatggattt ttctcctgct
     6721 gcaagtatac ccatatgtcc ccctagacat ggaccacaag ttggtgtaga aactgctgct
     6781 cctgcctcta taaaagtggt aatataccct ttttctatag cttcaagata tactttttga
     6841 gttccaggaa atatcataac tctaactcca tctgctactt ttttgccttt cattatctca
     6901 gctactactt caaggtctga tattcttcca tttgtacaag agcctattac aacttggtct
     6961 atctttatat ccttatctat ctcatctact gttctagtat tttcaggaag atgaggaaag
     7021 gctactgttt cttttagttc agctaaatct atttcgtata cttcatcata gactgcatct
     7081 tcatctgctt catatatatt tacatctttt gtcatagttg aacacttatg tgaatttata
     7141 tattccatag tcttatcgtc tactggaaaa attccatttt ttgctcctgc ttctattgcc
     7201 atattacaaa tagtaaatct atcatccata gataagtatt ctactccatc tccacaaaat
     7261 tccattgact tgtaaagtgc tccatcaaca cctatctccc ctattatatg aagtattata
     7321 tctttaccac ttatccattt atttggttta ttcttcaaaa caaattttat tgctccagga
     7381 accttaaacc aacattttcc tgtagccata cctgctccca tatcagttga acctacacca
     7441 gtagaaaatg ctcctaatgc tccatatgtg caagtatgag agtcagcacc tataattaca
     7501 tctccagcag ttactatacc tttttcagga agaagaacat gctctattcc catatctcct
     7561 acatcaaaaa aatttacaac tccttttgat tttgcgaaac ttcttgtaaa tttacattgt
     7621 tctgcactct ttatatcttt attaggtgta aagtggtcta aaaccatcac tactttagtc
     7681 ttatcataaa catcttcaat tcctaatttt tcaaattctc taatggctac tggtgatgtt
     7741 atatcattac ctaaaactac atctaaatct gcttcgatta attgcccttt cttaacttca
     7801 tttaatttag catgtttggc taatattttc tgcgtcatag tcatccccat tttttatttc
     7861 ctcctcaata taacttttat ttattgcatt cataagtgca ttaatagctg ctgtatttat
     7921 gttttccgat atacttacac caaaatagac ttcattattg tgctctattc ctacataagc
     7981 tacccctctt gaatgtgacc cttcctctaa tgcatgttcc cagtaatatc taaatttata
     8041 atctttcatg ccacattgct ttagtgcatt attaaatgaa tctacaggtc catttcctat
     8101 accaacaatc ctttgttcat ttcccatata acttattctt gcagtcatct caatcatgtt
     8161 agtatcatta gaatcatcat tttcatagtt taattcatcc attgatttta ttttatactt
     8221 cttaacttta taagggctct caacttcaat atattctttc ttaaacaaat taaatattgc
     8281 ttcactacta agttcttccc caattctatc agattccatt ttgactacat ttccaaaatc
     8341 agaatgcata ttcttaggta tcataaatcc ataatctgtt tccattatat aaacagctcc
     8401 tccttttcca gattggctat ttatccttat aatttctttg tattctcttc caatatcatg
     8461 agggtctatt ggtaaatatg gaacttccca gtaatcatta tctctgtttt tcattgctat
     8521 catgcctttt ctaatagcat cttgatgtga acctgaaaaa gcacaatgta caagattacc
     8581 tgcatatgga tgtctatcat gtaccataag ttttgtacag tcttcatata tacctattat
     8641 cttatctata ttgctaaaat ctagctctgg gtctattcct tgtgtataaa gattaagtcc
     8701 cacatttact atatccatat tcccagttct ttcaccattt ccaaatagtg ttccttcaag
     8761 tctatcggca ccagccaata atccaagttc acttgcagcc gtacaagttc ctctatcatt
     8821 gtgagtatgc aaacttagta taatagaatc cctacaactt atatttttac aaaaccattc
     8881 tatttggtct gcatatacgt ttggtgttgc catttcaact gttgatggaa gatttattat
     8941 tacttttttt tgaggagttg gtttccaaac atctatcact gcctcacata tttcaagtgc
     9001 ataatccatc tctgttcctg taaaactctc tggtgaatat tcaaaagtaa attctgtttc
     9061 tggatatttt tttacttctt cattaaataa ttttgctcct tcaactgcta tatctattat
     9121 ttcttgttta ctcatattaa aaaccacatc tctttgaaga acagatgtag agttatataa
     9181 atgtataatt gcttttttac atccccttat tgattcaaat gttttttcta taagatgagc
     9241 cctagattgt gtaagtactt gtatagttac atcatctgga atcatattct catctattaa
     9301 ttttcttaaa aatgtatact ctgtatttga tgctgatgga aatcctacct ctatttcttt
     9361 aaatcctgta tcaataagca ttttgaacat tctgactttt tcatttacac tcataggtgt
     9421 tggcagtgac tgatttccgt ctcttaaatc gacactacac caaattggag ccttaaatat
     9481 ttcattatct ggccatttac gatttactat ttgcatttta tcatattttt tatactttcc
     9541 acacttcatg ttatttcccc ctttttttgt tttttgtatt cagtatacct catatcgacg
     9601 caatcctgca caattcataa ggataaatgt caattttatc attagaataa aaaaaacctc
     9661 atctctaata aaattagaga cgaggttttg ctcgcggtac cactctattt agctttctaa
     9721 aaagctccct tagtaatagc caatacaata attataatga ctatatttcc tataacgtgg
     9781 aattactccg attattctaa gatttaaatc ttagaaaaca gctcctagac aagttcagaa
     9841 ctatcaacta ctaaatcaca ccatccttta gctctctgaa agtttcattg ttcttactac
     9901 ttctattcat cactttttta atcatttaaa ttttctaaat attttgattt aatagttatt
     9961 atatacacat taaaatgtat tgtcaacaca aaaaataatt atctcaattt tttatttttg
    10021 ataagcaatt ctataaaaca tgctaactat tgaaaacagt atgatattat gccttaaact
    10081 ttttcatctt ttcatctatg atattcaata attttttttc atcttccaaa ctcaatgccc
    10141 ttaatctaat tttataatta gattcgtcag tgtatatatt taatatattt tttactactt
    10201 ctattttttc tattatctta taattaaact tttgactttg tttagatttt atactgaata
    10261 tacattgatt atttattaat attgaatgat tatcgagagt aatatatact tttccctcat
    10321 atttatttga aaaatcacga ccttgtttaa atagaaaaac tgctgttatt atacataaaa
    10381 tatataatat tgtcgttgaa tatataaaaa ttgtagctaa aattataagt gctaaaacca
    10441 tatatatagt cattcctttt ttaaaataac cattgtcata ataattcata tagataaact
    10501 tatttttact caaatttttt cactcccaag attctaaaaa tttatatcaa aaaattctat
    10561 aatttcatct tcatgataat ttatgactaa ttcatctgga aaatctactg cttctaaaac
    10621 tttttctgca ttttcaaatt ctcctataga ataacatata tgagagtcag taccaagaat
    10681 tactcttgca ccatatgttt tacacaatgt caacatatga cttacatttt cccaagtacc
    10741 cgttctatga gagtttgaac ttaatgatga attatttatt tctaaaagga tatttttatc
    10801 tttagctttt tttactatag gttcataatc taaaggatac ctactgtcat ctggatgtcc
    10861 aattattttt accttaggtt tatccataac ttttaaaata gcatttgtat ttttttcttt
    10921 tgtaccagag gctatacaag gtctatgcaa acttgcgatt atataatcca aatgtttcaa
    10981 catatcttct tgaacatcta aattaccatt ataatccatt atatttcctt ctattcctct
    11041 aagaatcttt acgccttgca cttcacgtgg aagcaaatgc aaattataaa aatagaatgg
    11101 atgtggtcct cctggcatat taggtccatg gtctgatatt cctaagtatt ttatattctt
    11161 cttactcgcc tcttcgacat tttccttgaa agtactatgt gcatgtccac ttattagagt
    11221 gtgacaatgt acatccataa tagacttttt cattaaattt cctcctaata ttttacataa
    11281 attcgtgaaa atagctaaag ggctatttca aaactaaagc tgtcataata gacagtgtaa
    11341 cgttttaaaa cagccccatt ttcaattatt ttacacttct aaatctttaa atttatcttt
    11401 aaataattct ccaatacttc ctaaagattc ctctacttct aggtattctg ttatatcctc
    11461 ttctggctct ctagttgctt cttttattga aaccaacatt cttttagtct ttggtttaaa
    11521 atcaagaatc ttaactttaa cctcatctcc aatattaaca acattagtaa ctttagccac
    11581 tctagtatca ctcaattcag atattggtaa atacgcatct acaccttctt taatttgaac
    11641 aaaagcccct ttttctatta ttctaagaac tttagcattg acaacatcat caatttgtac
    11701 ttcttttgct attaaatccc aagggtcatt atttatgtct tttaatgcca aggcaatttt
    11761 tttagtctct ttatttacat ccaacacata aacttctact tcttgtccct ctgaaacaac
    11821 atcttcaaca ctttcaactc ttgtccaagc taaattattt atatgtgcta atccttcaat
    11881 cccaccaata tccacaaatg caccataagg cattatcttt gtcaccttac catctctttt
    11941 ttgtccaact tcaagagaat taaataagtc ttctttagct gctttgatac gagctttttc
    12001 ttcttctctt tcttgcttaa ttcttgctct ttcagcttct ttttctgcct taatttgagc
    12061 tcttctttct tctctctctt tatttatacg ctcttgtaat acatctctat gagatgctac
    12121 aagtctattt tttctaacat ccaattcttt tatataaact tctaagttaa gaccaacaaa
    12181 tttagatgta tctgtaataa attttgtatc aagttgagaa attggtataa aaaatgtata
    12241 tgtattgtaa ttagcaaata cacctttatc tatattcttt tcaacattta cagttattat
    12301 tctatgttca tcataagcct tttgtaactt ggcaaaatca tttcttttgt caagttgtaa
    12361 tttagataaa gttattgtac catctttttg agatactttt gttattacag cagttatttc
    12421 atcacctatg tggtatatat cttctatata ttgatttttt tctatgttca attcacttat
    12481 aggtattatt ccatcaaacc catagtctaa tcctaattgt acttcatcat ttctcactgc
    12541 agttattttt ccagttgtca attctccaac tttcactttg ctgaatactt gttcttgctg
    12601 gtcaagtaat tcttgcattg ttaaatcatt ttccattata aacatccttt cctcttattg
    12661 attatcatat ctgtaaatat tataccatta atattgcaaa tacttacatt tttcttacta
    12721 taatttttaa aataaattca acttcatata tttatacatt atagaaaata tcttattaaa
    12781 ttaaaataca aattctaatt tttatctaat aaaatatttt cataaaaaat ttatattgta
    12841 tatcttattc ttttattgct ttaggttttg atagaaaaca tttataaaat ataaagaaag
    12901 aaattgctgt tatagtagca gctgttatat ctgcaactgg ctctgctaaa attactgcaa
    12961 aaagtttttc attaaagaat gttgggagta taaatattaa aggtattaaa agtacaatct
    13021 ttctaagtag agctaaaacc aaagatattg ttgcttttcc aagtgctaaa aatgtctgtt
    13081 gacaagctat ttgaatccca aacataaaag caccagcaaa atatattttt atactccaac
    13141 tagtcatact aagtaactgc ggattcttat taaatatact aacaaaaaat gcaggaaata
    13201 tcattaataa aagccataaa atagtagaat atgtaaaaca tgacaacaaa cacaacttaa
    13261 atgtcttttt tactctatca agttgacctg aaccataatt ataacttatt attggttgtg
    13321 ctccttgtgt aacccccata ttaggaagca taagaatttg cattatactg ctcattatag
    13381 ccattgaacc tactgctaaa tctcctccat acatttgtaa tttactattt aaggctataa
    13441 gtactaaact ttctgtagat tgcattataa atggagagat tcccaaacca agcactggta
    13501 agatgatact tgcttttggt atcatatact tcttttttat tttaagtata cttttctttc
    13561 caaagagaaa cataagtacc caaatagcag aaacgccttg tgcaattata gtagctaatg
    13621 cagctccttt tacacccata ttaaagccaa atataaaaat cgggtcaagt attatgttta
    13681 ttaaagcacc tatagcaact gtcatcattc cagttgtagc aaacccttgg gtatttataa
    13741 aagtattcat acccattgaa atctgaacaa acactgtacc tattaaataa atatttaaat
    13801 agtccattga atatccaatt gtagattcac ttgctccaaa catccaaagt aaaggctctt
    13861 ttccaatctt aaaacctata gtcaaaagta ttgctaaaat caccagtaca gaaaaactgt
    13921 tactcattat tttctctgcc tcatcattgt tttgctcacc catttttata gcagctaatg
    13981 gacctcctcc cataccgatt aaataactac atgcagttat tataattatt attggaaatg
    14041 ccactccaac accagccata gcaacttctc cattttccat tctaccaata aaaatcctat
    14101 cgactatgtt gtataaaaca tttacaattt gtgcgataat agcaggtgta gcaagtttaa
    14161 ataataattt acccacactt tcactaccta agttagtgtt tgaattttcc attttaaaac
    14221 ctcctcaatc caataattaa aatgtatcac taaaatttta ttctatataa aaatttcatt
    14281 ttattagcag acaaatttag agtactttcc ctacaagtaa tactatacta tatttctttt
    14341 gccatagtaa acattttaga actaactgaa gttaaatact ttatctcatt ttttatttat
    14401 tattaaaaat ttttcacaca tactcataaa aaaactatcc aagtatatta cttagatagt
    14461 tttatattat atgtaaagaa agagctgaaa ctataacccc tgataacaaa ttaccaagaa
    14521 atactcccat aaaagcatct tttattctca tttttaatat ggaagctata gcagatgcag
    14581 tccatgttcc tgtagttggc agtggtatac ctacaaatag tattatacca attatcgaaa
    14641 cactttttaa tttcttcatt cttgagttta tttttctatc aattacatca gcaatccctt
    14701 taaatagttt cttccctctt aaaaattgta atacatgtct gaatgtcaat atcaagggaa
    14761 tcgataccaa tgtagaacct attacactaa atacataaac ccatatagga tttaagccca
    14821 ttgcaatacc tataggaatg gctcccctca attctgttac aggaaccata gataaaatta
    14881 atatgtgtaa atatcccaaa ctattccctc ctattctaag tgacattaag ttatgaattt
    14941 atttgctcta taacctcacc atccttttta ctaactaaaa atgcattttt agtcaatgaa
    15001 agcattggta aatcactctt agagtctgaa tatgcatatg aattttcata atcaatctct
    15061 atcccaagtt tacctaatac agcctttatt ctttttaatt tttcaattcc cttacaattt
    15121 tctccaatga attgattttt atatcttgaa ttttcataaa aaaactccgt gcctataacc
    15181 tcgtctgcaa gaccataata cttaaaatat ttcatatatg catatggaga tgcagttatc
    15241 ataattataa cattatcttc ttctttattt ttgtaaataa cctttttcat agattcgtta
    15301 atttttttca ttatgcaatc atcaaaaaac ttttttaaat cttcttcact aaaatctact
    15361 attggataaa agattgcctc ttttgccttc ttcaaaggta tcattctaat taaatacata
    15421 aatagaataa aaataatgta tggcaacttt ataatagttt taaaggtttt attttttaaa
    15481 gagtaaataa aaaaatctat catgctatca gtatttataa cagtataatc tacatcaagt
    15541 aataatacac tttttttcat aagtatttcc ccatcctatc actaaaaata tcactaaaaa
    15601 atcaatatta ttaaacatgt aattatccat aagattacgt ttatttttaa agcattatct
    15661 tttaggacaa tatcagtagg attattttca tttgtagtgt taattatata attatatcta
    15721 agtacaccat aaactacaaa tattgttgta aatatcatat gtggcttttc tggattactt
    15781 gtagaataca atgcataaca tacaattgta gaacttaata taactatcat catttgattt
    15841 agattttcta tgtcataatc ttccaatatt tttctatgtt caactgcatc atctcttaga
    15901 gtttctattt cttttttacg ttttccaaga gctaagtaca gagataagaa aaatgtacat
    15961 aaaattatcc aatttgataa actaacactt atggctacac atcctgcata aaccctaagt
    16021 ataaaaccaa gagatattga aaacacatct aatagtatta tattctttag tttaagagaa
    16081 tataatatat tgtttatcaa atagagactg agaattatag aaagattaaa actaacaact
    16141 gttgataaac agactgaaat taaagctaat actacaaata gtatattagc actttttttg
    16201 cttattcttc cacttgccac tggtctatta cattttttag gatgtttttt atctttatcc
    16261 atgtctatag catcattcag tgcatatact gatgatgaca ttaggcaaaa acacacaaac
    16321 gcaataaacg tatttaaaaa taaatttata tttagtatgt tgtttgaaaa aattatagct
    16381 gaaaatacaa agaaattctt tatatattgc tttattctca ttaactttat ataatctgaa
    16441 attttagtaa gaagccttat acttgtattg gtctgtttca taaacttact accctttcaa
    16501 tattattttt taaacaggat atgattttat ccctatgttt aaaatttcta taaatccatt
    16561 gacattactg attactatag taaccaataa cagcgataga aatatattat acatattctt
    16621 ttcatttttt ctaagcgctt tcgtaaagta agccaataaa attataactg caaaactaaa
    16681 atttatagcc ataatacttg aattgactag attatatcct actataccat gtaaagttag
    16741 attgaatata attattccca tacatagctt aggaactctt ttttctgaat tttcaataac
    16801 tgataaaaca caaaaacata aagctaataa tgtaagaatt actggtattg tagcaacttc
    16861 tccattttgc aaaaataacc cttttttaat gcttgctcca ggaaaataaa aaaccgaata
    16921 caataatctc tctataatca ttgcaatctt ttccaaaatt ggttctccac ttataaattt
    16981 cgtatcatac tgtattacat ttccaaggtt cataaaactc tcataagact tcgttgaaac
    17041 tacacaaata tatgccatta ggataaatgt aattaaatgt tttaacattt ttcctatttt
    17101 taatttaaac tcaaatatca tattaaaaaa atacaaatat atattactaa tagttattcc
    17161 aaatagagga atagctgcta attctactaa ataagaattt tttcctttca tcttatttgc
    17221 aataactatg aaaaatatta atgaaaattg gctatatata aatctctcta catttaaagt
    17281 tataaataac tgt
//
LOCUS       DAFAZV010000069        17090 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFAZV010000069 DAFAZV010000000
VERSION     DAFAZV010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 17090)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17090)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17090
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.069"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(180..548)
                     /locus_tag="KOU88_003553"
     CDS             complement(180..548)
                     /locus_tag="KOU88_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213384.1"
                     /translation="MKKIPKSELLVMNFIWDKGIDKIPAREVANYMEISHGWTKGTTG
                     KVLSRLSDKGFLEFEKDGRNTLYTIKVKHEEYLKFETKDFLELIHKNSIHSFISSLDC
                     GNEISDDDIKELEQWLKKRK"
     gene            complement(1076..1498)
                     /locus_tag="KOU88_003554"
     CDS             complement(1076..1498)
                     /locus_tag="KOU88_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBK3213385.1"
                     /translation="MNTFKTEVLLKYSAKDIFNIFTKSARLNFPNFNEKKAVGTFVQQ
                     KNNKRFKVEITNFEKNRVYEIKTSNKRESTITRYELVHIDLENTKLIFIESESKRNIF
                     GKINSALIRVLFGKRQPEEFNKFIKKLEMELENNSVNL"
     gene            1976..4879
                     /locus_tag="KOU88_003555"
     CDS             1976..4879
                     /locus_tag="KOU88_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK3213386.1"
                     /translation="MELRDKLVNIINTENKKDPLTDVQIAKFLSTTRENITNLRKELN
                     ISNSRQRRYPYLKSAISAILQKNKNISISEITRELMTEGFNISRRVVEELLPKESLEM
                     DVVEESEEESNDPFETLIGNKGSLRNAVEQAKSAILYPPKGLPTLIIGESGVGKSLFS
                     RHMYEFAKQKKIVKESSNFVVFNCADYSDNPQLLLSLLFGYKKGAFTGAEYDTPGLVE
                     EADEGVLFLDEIHRLPPKGQEILFSILDRGKFRRLGETNAERKVSIMLIGATTENVET
                     NLLLTFRRRIPMLITLPPLHDRLLKEKIDLIYNIFQQECNRINAKIFVDKNVIEILAL
                     KKFSGNIGQLQNMIQVLCARAFMKFINSKDEDSESIVVVDINEVLKLKDSFKDAAFQE
                     IEYTEIRKYLKNAIFIPFNLEESSVKGSLLSDEYILPEDIYKTIEKKYYDLKSLDIED
                     IDIENILWTFILNRFADLKFNLDSNEEIFSMSDLNSFVSDSLVKLVKELMNDIVEKNM
                     NLEVNKNMFKYLAIHLEEAIKRIKLNQKIINVNLEKIKIDFSKEYEISKSFAIKIEES
                     IGIKIPDDEIGFITLYIKSALKNEVKKDKVGLIIISHGRIATETVNVVKELLGVKFPV
                     AIDMPLDEKPINIYNKAVELSKIIDQGKGILFLVDIGSLTNIGQIVNKRTNISTKTID
                     RVDLLMALEATRKVSMGEEELDEIFFSLLKDRMGYNYELEKHIDKSNAIITLCLTGEG
                     TAKYISKTLEEKYDNTKCYQMSALDENLFCKIENLKETNNILAIVGTINPKIPGINFI
                     PYNKELFKNLDIYLSKSKQQDDRPIKSYERMLDEDLVIFEPDIYFKKDLLEYVCSILI
                     NKEYVEKDYLDSVLHREEMLPTYSKGAIGVPHGDSSTVNSTRFVFVKLKNPIDWGVGN
                     VNFIFMPVFQANDKEIVKNVLEILKDAEFMNNANKCFDKDAFRRIIFDKFKHL"
     gene            4912..5358
                     /locus_tag="KOU88_003556"
     CDS             4912..5358
                     /locus_tag="KOU88_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3213387.1"
                     /translation="MNVDLISLGLESNDYESVIEELGSIMCKKEYVKETYINAVLERE
                     RTLPTGLDIGEMCVAIPHTDSKHVNESNVAVGILKNPVKFNSMIDPKDRLDVELVFLL
                     AVKNPDSQVKLLKDLMSVFQNIKLLKNIKNASTKEEVAKLLDFIEI"
     gene            5481..5783
                     /locus_tag="KOU88_003557"
     CDS             5481..5783
                     /locus_tag="KOU88_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3213388.1"
                     /translation="MKQFNVLSVCGSGTVTSSMVAGKLKEVLGNKGISITTTEARPTE
                     ALNLAQSGRFDFITFTSPLQTGDYGIPTINAFACLTGIGEEAFFEEVLTVIEGIDK"
     gene            5964..7370
                     /locus_tag="KOU88_003558"
     CDS             5964..7370
                     /locus_tag="KOU88_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBK3213389.1"
                     /translation="MLEFMKSIIDTFGSAIIVPIIIFIIAKIFKVTTKKSFLSAVYAG
                     VALQGFTLILNSFTPIITPVINRMVESTGVNLPVFDVGWQATSLVAFSTSAGMIYLGL
                     GILLQTILFLIKWTDVFQPSDLWNNYSYMVWGAMVIGVTGNFPLGIACMVLLNLYSLL
                     ISELVAKRWSSYYRYPNCTIIAMHNVEASVFAVFADPIYNKLGLNKIKLNPKELEKKL
                     GFLGEPITLGLFLGMFIGILGNMTRINTMEAWGEIMKVGISTSAVMAIFPKVASMFAQ
                     AFAPITEAARKIMQKAGNREWYIAVNDAVGYGEPATLISGLILIPIMLVIAMVLPGNK
                     VLPVVDLLAIPYMVQGLVAIHNGNIPKVLVSGIIWFGLGLYVCTSTAPLFTDMATNIG
                     VAIPAGAMLITSFNILGKPLMGLVFFAFLSANPIYIGLSVVIYFVLWALFRKNKTSIL
                     DYLEKQALKNVEEEPVAV"
     gene            7714..8772
                     /locus_tag="KOU88_003559"
     CDS             7714..8772
                     /locus_tag="KOU88_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012101107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBK3213390.1"
                     /translation="MGDKMRASVLYNVGDVRYEMVDIPEITDTQVLVNVKYVGICGSD
                     LPRSMVSGLSGNTKYPLILGHEFSGEVVKIGEKVKHINVGDRVAVAPLVPCRKCDYCN
                     EGNFGLCDDYNIIGTRVNGAFAEYVRVPEEHILKLPDTLDYETAAGIEPATIAYHGIS
                     KSNIRVGDSVVVLGCGPIGQFVIQWAKVFGASKIIAVDIFDEKLELSKLLGANYILNS
                     KEVNVIKEIKKITNGGADVVIETAGSRFTQEQSLFVAKKRGNIVFVGISHTELPLSAD
                     ATECILRGELTLKGSWNSYTSPYPGRAWTATLDFMGKGDIIFKPMISHKIGLNEVGDF
                     LSKMSKREINFNKILVEI"
     gene            8871..9557
                     /gene="araD"
                     /locus_tag="KOU88_003560"
     CDS             8871..9557
                     /gene="araD"
                     /locus_tag="KOU88_003560"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBK3213391.1"
                     /translation="MLENLKEEVLKANLELPKKKLITYTWGNVSGIDREKGLVVIKPS
                     GVEYSNMTVEDMVVVDLEGNIVDGKLRPSSDTPTHLVLYKEFEELGGIVHTHSSWATI
                     WAQIGKSIPSCGTTHADYFYGSIPCTRKMTREEICNEYEKETGNVIIEEFMGRNPIHC
                     PGIIVNDHGPFTWGKDANEAVHNAVVLEEVAKMAYYTELMSPDNIMDKVLMNKHFSRK
                     HGKNAYYGQK"
     gene            9575..10222
                     /locus_tag="KOU88_003561"
     CDS             9575..10222
                     /locus_tag="KOU88_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBK3213392.1"
                     /translation="MLDSLKGKIVEIAIKAEHYGLCKEKTGNFSIRDKDTGYILITPS
                     GIGREELKVEHICVLDLDGNVIEVEKGIKPSSEVLMHIEIYKTRENINAISHTHSLYA
                     TAFSVAKKPILPIVYESVNYGGYVDIAPYERPGTLKLAKSVSKLLIDTDACLLERHGL
                     TTVGNDLDEALLKSRYVEEVAEIYYRSLVLNQFKELEVVDVDEFKSWKYPEEIKF"
     gene            complement(10395..11762)
                     /locus_tag="KOU88_003562"
     CDS             complement(10395..11762)
                     /locus_tag="KOU88_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBK3213393.1"
                     /translation="MNLIDILNKVDAFIWGPPLLVLLVGTGILLTVKLGVVQITKLPR
                     ALKLIFSAENKGSGDVSSFAALCTALAATVGTGNIVGVATAIKAGGPGALFWMWIAAF
                     FGMATKYSEGVLAIKYRTKDKNGQVSGGPMYYIVNGMGEKWRPLAIFFAISGILVALL
                     GIGTFTQVNSITDAINNSFGIDPRITGVVLAVFVALVVFGGLKSISNVATKIVPFMAV
                     IYVVICGIILISFWNKIPETFMLIIKSAFTPTAATGGFLGATMSLAIRNGIARGVFSN
                     ESGLGSAPIAAAAAKTEWPAEQGLISMTGTFIDTIIICTLTGFSLVISGVWCSDLNGA
                     VMTQAAFNGAIPTFGPILLTVSLTLFAFTTILGWSYYGERCFEFLFGVKGMNGYRTVF
                     VAMVLLGAFLKLEVVWIIADIVNGLMAIPNLIALLALSPIIVSETKKYFEHINSPENQ
                     IKKNA"
     regulatory      complement(11952..12040)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            12468..14588
                     /locus_tag="KOU88_003563"
     CDS             12468..14588
                     /locus_tag="KOU88_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBK3213394.1"
                     /translation="MGKILVLAEKPSVGRDIAKVLGSKNEKNGYIEGPKYVITWALGH
                     LVTLADPESYGERYKSWSLEDLPILPKHLKTVVIKKSGKQFNTVKSQMNRNDIDEIVI
                     ATDAGREGELVARWIIEKSQVKKPIKRLWISSSTDKAIKDGFAKLRSGKEYENLYYSA
                     IARAEADWIIGINATRALTTKYNAQLSCGRVQTPTLAMLLKREEEIRNFKPKEYYGLE
                     LIATKGNSDIKFIWNDKNNNSSTFSKEKIESTLKKVKGVDIKISEVNKSYKKKYSPAL
                     YDLTELQRDANKMFGFSAKETLSIMQKLYEHHKVLTYPRTDSRYLTSDIVGTLKDRIK
                     AVNISDYSKICNRLLKSNIIANKSFVDNSKVTDHHAIIPTEQKVFMSDFSDKERKIYN
                     LVVKRFLAVLSPPFEYEQTTISATVEGEIFKAKGNKVINLGWKESYKDIEDEDEYESI
                     PNILEKDVLKVKGLKITSGKTNPPPYLNEGTLLTAMEKNGLGTVATRADIIEKLFNSF
                     LMEKKNKDIYITSKGRQLLDLVPVDLKTPELTASWEKKLLDISKGKLSKNTFINDMKD
                     YSKDIVLEVKNSDNKFKHDNLTKNRCPECGKFMLEVNGKKGKMLICEDRECNTRKTIS
                     QVTNSRCPNCHKKLELRGEGEGRIFTCSCGYREKLSSFNKRKQEEKQKASKKDVNQYL
                     KNQNKNQETFNNPFAEALAKLKNK"
     gene            14692..15945
                     /locus_tag="KOU88_003564"
     CDS             14692..15945
                     /locus_tag="KOU88_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FliS"
                     /protein_id="HBK3213395.1"
                     /translation="MDLSGIFKYYCKECENTWNNSSVELFENIETYSKDSQKKREKEL
                     DKLLNTISVHLERYPSDAVLRKMWVKKGEVFLQKTLEKENIFKLEKMDVEDRKKFLDI
                     TKQFIRDARKFDDDLPIGDIMQAMRNVWISNALQLLFGKEVYYSKANFAYSMLYPYTD
                     NYLDSTNIDKNDKILFNNWLEKRLLGEHIKSKDYHESKVSQMIDYIESVYPREKFTEV
                     YESLLLIFKSQVNSLKQHGKENHLCKEDLLSISIEKGGSSVLVDGYLISGLMTKEEIE
                     FCIGYGFLLQISDDLQDIKEDLKYNHKTIITEMSKEGTLDKVVNKLINFTIELIDSFK
                     INNKNKSVITMIKNDCLMLILFSVVYNAEFFSVGYIKEVEKFIPYTIDYSLEIEEKIK
                     EKFKNIDVLNNENEYKEMIDIICAE"
     gene            complement(16099..>17090)
                     /gene="ytvI"
                     /locus_tag="KOU88_003565"
     CDS             complement(16099..>17090)
                     /gene="ytvI"
                     /locus_tag="KOU88_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sporulation integral membrane protein YtvI"
                     /protein_id="HBK3213396.1"
                     /translation="IVLKFLLPLLMPFVISFIIASILRPIIRLITNNTNLNRTLISIV
                     ILLIFYGLCIFLLVSFGVKIFASVSDVFFRLPEIYKSSIQPTLNTLFSKIDASTPNVN
                     LALILGWDNISQSMMSLVASISTNALNAIASIASKTPAFMLKLIITLIASFFFTFDYQ
                     KIVNFILKQFPEKSQFMIINIKNSSINALLKLLKAYAILLSVTFIELLIGLTILKVEN
                     AFTISVIIALVDILPVLGTGSILTPWMIISLINGNINLAIGLLILYIIITVVRQILEP
                     KVVGHQIGLYPLITLMCMFVGAQLFGIAGLFGFPIAATIIKNLHDNGIITAFK"
BASE COUNT         6730 a         1955 c         2818 g         5587 t
ORIGIN      
        1 tttaaattta ttttagatat aaacatcatt ctgactacta ttaaaagaca taaaaaataa
       61 ttaaacttaa aattatattt gcttatcttt ttagtaaata aaatgaaaaa aagaattagt
      121 ggacttatgt aaatattaaa tttaataact tctataaata attccataaa atacgtctcc
      181 tattttcttt tttttagcca ttgttcaagt tcttttatgt catcatctga tatttcattt
      241 ccacaatcta atgatgatat aaagctatga atagaatttt tatgtataag ctctaaaaaa
      301 tcctttgttt caaattttag atattcctca tgtttaactt taatagtgta taaagtattt
      361 ctaccatctt tttcaaattc taaaaaacct ttatcactta atctagaaag tactttacca
      421 gtagtacctt ttgtccatcc atgagaaatt tccatataat tagctacttc tctggctggt
      481 attttatcta tgcctttatc ccatatgaaa ttcataacta acaactcgga ttttggtatt
      541 tttttcaata taatcactca cctttaactt gattatatta gacaaatgtc taatagtcaa
      601 tataatatat cataatgtat aaataatctt tatattattt tatgcttgag aactaagtag
      661 tatagattta tagataaaaa agatgttgag agttttatgg aagaggggaa tatattttct
      721 attagagata agaatatgac atatattttt tattgatttg tacaaaaata ctatatagtg
      781 aataaattaa tatcttttct aaattagaag aggataatct tattagataa agattatcct
      841 ctttattgaa agtttaaggg atattagaga ttattaattt ttctctcttt ttttaactaa
      901 aagcaataat acataaaatt attattgcta atgatactct taatgtggta tatagtcata
      961 gtgtcacatg tttatcaata gttttttcag taattattgt aacgaatagt aggactcata
     1021 aaatacttag aaatatgttt ttagataaat tttaaatata taatctaact tatatctata
     1081 aattaacact attattctcc aattccattt ctagtttttt tataaattta ttaaattctt
     1141 ctggttgcct ttttccaaac aatactctta taagagctga attgattttt ccaaatatat
     1201 tcctcttgct ctcactttca ataaaaataa gttttgtatt ttctaagtca atatgtacta
     1261 attcatatct agtaatagta ctttctcttt tattgcttgt ttttatctca tatactctat
     1321 ttttttcgaa attagttatt tcaaccttaa atcttttatt atttttttgc tgtacaaatg
     1381 ttcctactgc ttttttctca ttaaaattag gaaaatttag tcttgcagat tttgtaaata
     1441 tattaaatat gtcttttgca gaatatttta ataaaacttc agttttaaat gtattcatat
     1501 cgttttccct tctgtatata aatttaatat ttataagtta atttttaagt taaaatagta
     1561 taatatgcca tattaaatca tgttaaaact atttatatag ctaaaatctt acctatataa
     1621 gtatgtatac tatcatataa aaataaaatc ttaaaataga aagggttaaa aacacagttt
     1681 attataattt ttattgttga gtagatacgt actattatat atgattgagc aagtttttca
     1741 atcataaatt tataaagtat tttgcattaa aatttaaaca aagaattaaa ttatttaaga
     1801 ttatgaataa ctaatacatt tagtaaatta ctaaatatac aaaatgtaaa tacttatcaa
     1861 aatgtataaa tacttatgac atctagttac ttacagggtt taagtagaaa aaaatatcaa
     1921 agtaagtatg gcatgatagt tgcttatata tttatcaaga aaggagttat taagcatgga
     1981 gttgagagat aaacttgtaa acatcataaa tacagaaaat aaaaaagatc cattaacaga
     2041 tgttcaaata gcaaagtttt taagtacaac tagagagaac ataactaatt tgagaaaaga
     2101 acttaatata agtaattcaa ggcaaagaag atatccttat ttaaaatcag caatttcggc
     2161 aatattacaa aagaataaga atatttctat atcagaaatt acaagggaat tgatgacaga
     2221 aggctttaat atatctagaa gagttgtgga ggaactttta cctaaagaaa gtttagaaat
     2281 ggatgtagta gaggaatctg aagaagaatc gaatgaccca tttgaaactc tgataggtaa
     2341 taaagggagt cttagaaatg ctgtagagca ggctaaatct gctatattgt atccaccaaa
     2401 agggttacca acgttgatta ttggggaaag tggagttggt aagagtttat tttctagaca
     2461 tatgtatgag tttgcaaagc aaaaaaagat agtaaaagaa agctccaatt ttgttgtatt
     2521 taactgtgct gattatagtg acaatccaca attattatta tctttgttat ttggatataa
     2581 aaaaggtgca tttacaggtg ctgaatatga tacaccaggt cttgtagaag aagctgatga
     2641 aggagtttta tttttggatg aaatacatag attgcctcca aaaggccaag aaatactatt
     2701 ttctatttta gataggggaa agtttaggag attaggtgaa actaatgctg aaagaaaagt
     2761 aagtattatg ttgattgggg caactactga aaatgtagag actaatttat tattaacatt
     2821 cagaagaagg ataccaatgc taataacttt gccaccatta catgatagat tactaaaaga
     2881 gaaaatagac cttatataca atatctttca acaagagtgt aatagaataa atgcaaaaat
     2941 atttgtagat aaaaatgtga ttgaaatact tgcactaaaa aagtttagtg gaaatatagg
     3001 acaattacaa aatatgattc aggttctttg tgcaagagct tttatgaagt ttataaattc
     3061 caaagatgaa gatagtgaat cgatagtagt agtagatata aatgaagttt taaagcttaa
     3121 agattctttt aaagatgctg cctttcaaga gattgaatat acagagataa gaaaatattt
     3181 gaaaaatgct atatttatac catttaattt agaagaatca tcagtaaaag gaagtctttt
     3241 aagtgatgaa tatatattac cagaggacat atacaaaaca attgaaaaga aatattatga
     3301 cctaaaatcc ctagacattg aagatataga tatagagaat attttatgga cttttatttt
     3361 aaatagattt gctgacttaa agtttaatct cgatagtaat gaagaaattt tttcaatgag
     3421 tgatttaaat agttttgtaa gtgatagttt agttaaactg gtaaaagaac ttatgaatga
     3481 tatagttgaa aaaaatatga atttagaagt aaataaaaat atgttcaaat atctagcaat
     3541 acacttagaa gaagctataa aaagaattaa gctaaatcaa aagataataa atgtaaattt
     3601 agaaaaaata aagattgact tttcaaaaga atatgaaatt agtaaaagtt ttgcaataaa
     3661 aattgaggaa tcaattggta ttaagattcc agatgatgaa attggattta taacactcta
     3721 cataaagtct gctctaaaaa atgaagtgaa aaaagataaa gtagggttaa taataatttc
     3781 tcatggacgt atagctacag agactgtaaa tgtagttaaa gaacttttag gtgtaaagtt
     3841 tcctgtggct atagatatgc ctttagatga aaaaccaata aatatataca ataaggcagt
     3901 agaactgtca aaaataatag accaagggaa aggcatattg tttttggtgg atattggttc
     3961 acttacaaac ataggtcaaa tagtaaataa gagaaccaat ataagcacta aaactattga
     4021 tagagtagac ctcctaatgg cactagaagc aactagaaaa gtttctatgg gagaggaaga
     4081 acttgatgaa atattttttt ctttgctaaa agataggatg ggatataact atgaattaga
     4141 aaaacacata gataaatcaa atgcaattat aacattatgt cttactggag aaggaactgc
     4201 taagtatata agtaaaacgt tggaagaaaa gtatgataac actaaatgtt atcaaatgag
     4261 tgcattggat gaaaatttat tttgtaaaat tgaaaatcta aaagagacaa acaatatatt
     4321 agctattgtt gggacaataa accctaagat accaggtata aattttatac cctataataa
     4381 agaacttttc aaaaatttgg atatctatct atcaaaatca aaacaacaag atgacagacc
     4441 aattaaatcg tatgaaagaa tgcttgatga ggatttagtg atttttgaac cagatatata
     4501 ttttaaaaag gatttattag aatatgtatg ttcaattctt ataaataaag aatatgtaga
     4561 aaaagattac ttagattctg ttttacatag agaagaaatg cttccaacat attctaaagg
     4621 agctataggt gtgcctcatg gagattcttc tactgtaaat agtacaaggt ttgtttttgt
     4681 taaactaaag aatcctattg attggggtgt aggtaatgta aatttcatat ttatgccagt
     4741 ttttcaggct aatgataaag agattgttaa aaatgttctt gagatactaa aagatgcaga
     4801 atttatgaac aatgccaata agtgttttga taaagatgct tttagaagga ttatatttga
     4861 taaatttaaa catctgtagc catagcaaaa aaattgagag gagttagagt aatgaatgta
     4921 gatttaatat cattgggttt agaatctaat gattatgaaa gtgttattga agaattagga
     4981 agtataatgt gtaaaaaaga atatgtaaaa gaaacataca taaatgctgt cttggaaaga
     5041 gaaaggacat taccaacagg tctagatatt ggagaaatgt gtgttgctat tccacataca
     5101 gattcaaagc atgtaaatga gtctaatgta gctgtaggga tattgaaaaa tcctgtaaag
     5161 tttaattcaa tgatagaccc aaaagataga cttgatgtag aacttgtatt tttattagca
     5221 gtaaagaacc cagattcaca agtaaaactg ttaaaggatt taatgtcagt ttttcaaaat
     5281 ataaagttat taaaaaatat aaaaaacgca tcaacaaaag aagaagtagc taaattattg
     5341 gactttatag aaatttaatg taggagaatt ttataaataa aaaattaaaa tttaaacaat
     5401 caaagtaagt attatttttt taataggttt aatcttatat aaaataaaaa tttagagtga
     5461 aaaattagga ggaaattatt atgaaacaat ttaatgtatt atcagtttgt ggttcaggga
     5521 cagttacatc atctatggta gcaggtaaat taaaagaagt actaggtaat aaggggattt
     5581 ctattactac aacagaagct agaccaacag aagcactaaa tttagcacaa tcaggaagat
     5641 ttgactttat aacatttacg agtccacttc aaacaggcga ttatggaata ccaactataa
     5701 atgcatttgc ttgcctaact ggtatagggg aagaggcatt ctttgaagaa gttttgactg
     5761 ttattgaagg gatagataag taagttttgg agacgtgaat ttatagtatt taaatcaatg
     5821 atttagatac tataataagc taatattaac taaatatttg tggaaaaaac attttatatg
     5881 ttgtcataaa ttaaaaaatt ataaaaatag tcacttaagt attaaattaa gcttataaat
     5941 atttataagt aggagggaaa aagatgttag aatttatgaa atctataatc gatacatttg
     6001 gttctgcaat tatagttcca attataatat tcataatagc aaagatattt aaagtaacta
     6061 ctaagaaatc gtttctttct gctgtgtatg caggagttgc tttacaaggt tttacactga
     6121 ttttaaattc atttacacca ataataacac cagttatcaa taggatggtt gagagtacag
     6181 gagtaaacct accagttttt gatgttggtt ggcaagcaac atcattggtt gcattttcaa
     6241 caagtgcagg tatgatatat ttaggtcttg gtatattatt acaaacaatt ttatttttga
     6301 taaaatggac agacgtgttt caaccatcag atttatggaa taactattct tatatggtat
     6361 ggggagcaat ggttatagga gtaacaggaa attttccttt aggtatagca tgtatggttt
     6421 tattaaacct atatagttta ttaatatcag agttagttgc aaagagatgg tctagttact
     6481 atagatatcc taattgtaca ataatagcta tgcataatgt tgaagcttct gtgtttgcag
     6541 tatttgcaga ccctatatac aataaattgg gattaaataa aataaaatta aatccaaaag
     6601 aattagagaa gaaattaggg tttttaggtg aaccaattac tttaggtctt tttttaggta
     6661 tgtttatagg tatattaggt aatatgacga gaataaatac tatggaagct tggggagaaa
     6721 taatgaaagt aggtatatct acaagtgcag tgatggcaat tttccctaaa gtagcaagta
     6781 tgtttgctca agcatttgca cctataacag aagcagctag aaagattatg caaaaagctg
     6841 gaaaccgtga gtggtacata gcagtaaatg atgctgttgg atatggtgaa cctgcaactt
     6901 taatatcagg tcttatatta attccaataa tgcttgtaat agctatggta cttcctggta
     6961 ataaggtatt accagttgtg gatttattgg caattccata tatggttcaa ggtttagttg
     7021 ccatacataa tggtaatata ccaaaagtat tagtttcagg tataatttgg tttggattag
     7081 gattatatgt ttgtacatct acagcaccat tatttacaga tatggctaca aatataggtg
     7141 tagctatacc tgcaggagca atgttaataa caagctttaa tatactagga aaacctttga
     7201 tgggattagt tttctttgca tttctaagtg caaatccaat ttatataggt ctttcagttg
     7261 taatttactt tgttctatgg gcattgttta gaaagaacaa aacaagtatt cttgattatt
     7321 tagaaaaaca agcactcaaa aatgtagaag aagagcctgt agcagtttaa gtttataaaa
     7381 atgaaataag aataattaaa ggagtttata attgatttta tataagtatc agataatacc
     7441 tgagaaatat ttaaatgaaa tatagacttc tttttatttg ataatatttg taattataat
     7501 gcattgtatt tttatagttg agttttctgt ataacctgct atttaaaaca tactctttta
     7561 tatttataca gtaatgtggt ttaattttat aaaatgtaat ctctactggt aaaagacttt
     7621 gtatataagg catttgcctg aataaaccat ttatcttttg tatggcatag atattgctat
     7681 atagaagtat atagcatgaa aggagatatt tatatgggag ataaaatgag agcatcagta
     7741 ttgtataatg taggtgatgt cagatatgaa atggtagata taccagaaat aacagatacg
     7801 caagtgcttg taaatgtaaa atatgttggg atatgtggtt cagatttacc taggtctatg
     7861 gtaagtggtt tgagtggaaa tacaaaatat ccattgattt tagggcatga attttctggt
     7921 gaagttgtta aaattggaga aaaagtaaag catattaatg taggagatag agtagctgtt
     7981 gcaccattag taccttgtag aaaatgtgat tattgtaatg aaggtaattt tggcttgtgt
     8041 gatgattaca atataattgg aacaagagta aatggagcgt ttgcagaata tgtaagagtt
     8101 ccagaagaac atattttaaa actaccagat acattggatt atgaaactgc tgccggaatt
     8161 gaaccagcaa ctatagctta tcatgggatt tcaaagtcta atattagagt aggagatagt
     8221 gtagttgtgt taggatgtgg tccaataggt cagtttgtta tacaatgggc aaaggtgttt
     8281 ggtgcatcta agattatagc agttgatatt tttgatgaaa aattagaact ttctaaactt
     8341 ctaggagcaa actatatact taactcaaaa gaagtaaatg taatcaaaga aataaaaaaa
     8401 ataacaaatg gtggtgctga tgttgtaata gagactgctg gtagccgatt tacacaagaa
     8461 caatctctat ttgtagcaaa aaagagagga aatatagtgt ttgtaggtat atcacacaca
     8521 gaattaccac ttagtgcaga cgctactgag tgtatattac gtggagaact taccttgaaa
     8581 ggttcttgga attcatatac aagcccttat cctggaagag catggactgc aacattggat
     8641 tttatgggaa aaggtgacat tatttttaaa cccatgattt cacataaaat aggtcttaat
     8701 gaagttggtg actttttaag taaaatgagc aagagagaaa ttaatttcaa taaaatccta
     8761 gtagaaatat aaaaatttaa taaaaaattc taaaagcaat taaattttat aactatgaca
     8821 ttaaataaaa taaaaataat tttcttaaat aaaatatagg aggaagaaaa gtgttagaaa
     8881 atttaaaaga agaagtatta aaagcaaact tagaattacc taagaaaaag ctaattactt
     8941 atacttgggg aaatgtaagt ggaatagata gagaaaaagg attagtggtg ataaagccaa
     9001 gtggtgtaga gtatagtaat atgactgtag aagatatggt tgtagttgat ttagagggaa
     9061 atatagttga tggcaaatta agaccttctt cagatacccc gactcatcta gttttatata
     9121 aagagtttga agaattgggg ggaatagtac atacacattc aagttgggca acaatttggg
     9181 ctcaaatagg aaaatctata ccatcttgtg gtactactca tgcagattat ttttatggaa
     9241 gtataccatg taccagaaaa atgactagag aagaaatttg caatgaatac gaaaaggaaa
     9301 ctggaaatgt aatcattgaa gaatttatgg gaagaaatcc aattcattgt ccaggaataa
     9361 ttgtaaatga ccacggacct tttacatggg gaaaagatgc aaatgaggct gtacacaatg
     9421 cagtagtttt agaagaagtc gcaaagatgg cttattatac agagttaatg agtcctgata
     9481 atattatgga taaggttctt atgaataagc atttttcaag aaaacatgga aaaaatgcat
     9541 actatggtca aaaatgatta tctggaggtg aattatgcta gactctttaa aaggtaaaat
     9601 tgtggaaata gcaattaaag cagagcatta tggtttatgt aaagaaaaga ctggtaattt
     9661 tagtattaga gataaggata ctggatatat acttataacc ccatcaggta taggaagaga
     9721 agaattaaaa gttgaacata tttgtgtatt ggatttggat ggaaatgtaa tagaagttga
     9781 gaaaggtatt aagccaagta gtgaggtatt gatgcatatt gaaatataca aaacaagaga
     9841 aaatataaat gccatatcac atactcattc tttatatgca acagcatttt cagtagcaaa
     9901 gaaaccaatt ctaccaattg tatatgaatc agttaattat ggcggttatg tagatattgc
     9961 tccatacgaa agaccaggaa ctttaaaatt agctaagagt gtttcaaaat tactgataga
    10021 tacagatgca tgcttattag aaagacatgg gttgacaact gtaggtaatg atttagacga
    10081 agcattatta aaatcaagat atgttgaaga ggtagcagaa atatactata ggtctttagt
    10141 attaaatcaa tttaaagaac ttgaagtagt agatgttgat gagtttaaat cttggaaata
    10201 cccagaagaa ataaagtttt aatctaaata attttcattg aagtggttaa ttaaaatata
    10261 tgtattattt atatcaatta ctatgtttta ttatattaat taccgtattt tgtaaatata
    10321 tttattacat tttttcaaaa aaatatagaa tccgaaagcc atataaaatt gacttgggat
    10381 tctatacttt ttatttatgc atttttcttt atctgatttt ctggagaatt tatatgttca
    10441 aaatattttt tagtttcaga tactattata ggtgataatg caagtaaagc tataaggtta
    10501 ggtattgcca taagcccatt tacaatatca gcaattatcc aaacaacttc taactttaag
    10561 aaagcaccta ataacaccat agccacaaat acagttctat acccattcat gccttttaca
    10621 ccaaacagaa attcaaaaca tctttctcca taataactcc atcccaaaat tgtagtaaat
    10681 gcaaataatg ttaaactaac tgtaagtaat attggtccaa atgtaggaat tgctccgtta
    10741 aaagctgctt gtgtcataac agctccattt aggtctgaac accacactcc tgaaataaca
    10801 agagagaatc cagtaagagt acagattata atagtatcta taaaagtacc tgtcatagat
    10861 ataagacctt gttccgctgg ccattcagtt ttagcagcag cagcagctat tggagcacta
    10921 cctagaccag actcatttga aaatacacca cgagcgatac catttctaat tgccagtgac
    10981 atagttgctc ctaaaaaacc accagtagca gcagtaggtg taaatgcact tttaattatt
    11041 aacataaaag tttcagggat tttattccaa aaagatatta aaatgattcc acagattaca
    11101 acatatataa ctgccataaa aggtactatt ttagtagcta cattagatat acttttaagt
    11161 cctccaaata caaccaaagc tacaaatact gctaatacaa cccctgtaat tctagggtct
    11221 atcccgaaac tattatttat tgcatctgtt attgaattta cttgagtaaa agtaccaatt
    11281 cctaaaagtg caactagtat accacttata gcgaaaaata ttgcaagagg tctccatttt
    11341 tctcccatac catttactat gtaatacatt ggtccaccag acacttggcc atttttatct
    11401 ttagttctgt attttattgc aagaacacct tctgaatact tagtagccat tccaaagaat
    11461 gctgctatcc acatccaaaa aagtgcacca ggtccaccag ctttgatagc tgtagcaaca
    11521 ccaacaatat taccagtacc aactgtagca gctagagcag tacataaggc tgcaaaactt
    11581 gaaacatcac cactaccttt gttttcagca gagaatatta acttaagagc tcttggcagt
    11641 ttagttattt gaacaactcc aagcttaaca gtaagtagta taccagtacc aactaatagt
    11701 accagtaggg gtggtcccca aataaaagca tcaactttgt ttaaaatatc aattagattc
    11761 ataaaaacac tccctcattt tttttgcttt acataatcaa tagaattttt aatgaagtaa
    11821 ttgacaggaa ataagtataa tttattaata atttctagtg taataaaaaa agctaaatct
    11881 aaaaaagatt cagctctgga tgtacactaa ttagcaacca aaataaaagt attagtaaat
    11941 actgtttttg gtagataatc cctgtccttt tgcctgagag attgagcata aaagccttgc
    12001 cccttcggcg cccataatgg gtctctccag agttccgtaa attttacagt cctactttta
    12061 aaagtacctg agagtgttac tccttcggtg tgctatatag caactcttct ataaaatctt
    12121 aaccggatat tgatttgtca tagcttattg tattaataat attaatataa gtttttatgt
    12181 tttgtcaact aaaaaattaa aaaacaaaga aaaaatataa aaatgtaagc ctatttacga
    12241 attataaact tagaaagatg agtaatatac gtgaaaatga attttgtaat acacatacaa
    12301 atgaagtgta aaataagttt taaataaaaa aataataaaa tcttaaataa ttaattagat
    12361 atgattaaat tatggtaata ttatagttac gatattaaga aaagttctat ttagttagat
    12421 tttaatcgta atatgagatt atgtatagag aaaggatgta tttttagatg ggaaaaatat
    12481 tagtgctagc agaaaaacct tctgttggaa gagatatagc aaaagtttta gggtcaaaaa
    12541 atgaaaaaaa tggttatata gaggggccga agtatgtgat aacttgggca ctaggtcatt
    12601 tggttacact tgctgacccc gaaagttatg gagaaagata taaatcatgg agcttagaag
    12661 acctgccaat acttcccaag caccttaaga ctgttgtaat aaaaaagagt ggaaagcagt
    12721 ttaatacagt taaatcgcaa atgaatagaa atgatataga tgaaatagtt atagcaacag
    12781 atgcaggtcg tgaaggagaa cttgtagcaa ggtggataat agaaaaatca caggtaaaaa
    12841 aacctataaa acgtctttgg atttcttcaa gtacagacaa agcaataaaa gacggatttg
    12901 caaaattaag aagtggaaaa gaatatgaaa atttgtatta ctcagcaata gcacgagcag
    12961 aagctgattg gattattgga ataaatgcaa ccagagcttt gacaacaaag tacaatgcac
    13021 agctttcttg tggaagagta caaactccta ctcttgcaat gttgcttaaa agagaagaag
    13081 aaataagaaa tttcaaacct aaagagtatt atggattaga attaattgct acaaagggaa
    13141 attcagatat aaaatttatt tggaatgata aaaacaataa ttcttcaact tttagtaaag
    13201 aaaagataga atccacatta aaaaaagtaa aaggtgtaga cataaaaata tctgaagtaa
    13261 acaagtcata taagaaaaaa tattcacctg cactctatga tttaacagaa ttacaaagag
    13321 atgcaaataa aatgtttgga ttttcagcaa aagaaacttt atctataatg caaaaactgt
    13381 atgaacatca taaagtactt acttatccta gaactgattc tagatattta acatcagata
    13441 ttgttggaac attaaaagat agaataaaag ctgtaaatat tagtgattat tcaaagattt
    13501 gtaatagatt attaaaaagc aatattatag ctaataaatc gtttgttgac aattcaaagg
    13561 taacagacca ccatgcaata ataccaacag aacagaaggt attcatgagt gattttagtg
    13621 ataaagagcg aaaaatatat aatcttgtag taaaaagatt tttagcagta ctatctcctc
    13681 cttttgaata tgagcagaca actataagtg caactgtaga aggagaaata tttaaggcta
    13741 agggaaacaa agtaataaat ttaggttgga aagaaagtta taaagatatt gaagatgaag
    13801 atgagtatga aagtatacca aatattttag aaaaagatgt acttaaggtc aagggattaa
    13861 agataacttc aggaaaaaca aatccaccac catacttgaa tgagggaaca ttattgactg
    13921 ctatggaaaa gaatggtcta gggacagttg ctacaagagc agatataata gaaaaattat
    13981 tcaattcatt tttaatggaa aagaaaaata aagatatata tataacatca aaaggaagac
    14041 aattattaga tttagttcca gtagacttaa agacaccaga acttacagct tcatgggaaa
    14101 agaaattatt ggatatttca aagggaaaac ttagtaaaaa tacattcata aatgacatga
    14161 aagattattc aaaagatatt gtactagaag taaaaaatag tgataataaa tttaaacatg
    14221 ataacttaac taaaaataga tgtccagaat gtggaaaatt tatgttagag gtaaatggta
    14281 aaaaaggtaa gatgttgatt tgtgaagata gagagtgtaa tactagaaaa actatatcac
    14341 aagtaaccaa ttcaagatgt cctaactgcc ataaaaaatt agaacttcgt ggagaaggtg
    14401 aggggagaat cttcacttgt agttgcggat acagagaaaa gttgtcttct ttcaacaaga
    14461 gaaagcaaga agaaaaacag aaggcatcaa aaaaagatgt taatcaatat ttaaaaaatc
    14521 aaaataaaaa tcaagagaca tttaataatc catttgcaga agcattagct aagctaaaaa
    14581 acaaataatt ttaaagttat tattatacac aattataact ttaactgtat actagttata
    14641 tgtactgata taatatagtg tatagtttag gcatgaaagt agggctgtta aatggattta
    14701 agtggcatat ttaaatacta ttgtaaagag tgtgaaaata catggaataa ttcgagtgtt
    14761 gaattatttg agaatataga aacgtatagt aaagattcac aaaaaaagag ggaaaaagaa
    14821 ttagataaat tgctaaatac aatatcagtt catttagaga ggtatccaag tgatgctgta
    14881 ttgagaaaaa tgtgggtaaa aaagggcgag gtttttttac aaaagacatt ggaaaaagaa
    14941 aatattttta agttagaaaa aatggatgta gaggatagaa aaaaattttt agatataaca
    15001 aaacagttta ttagagatgc tagaaaattt gatgatgatt tacctatagg tgatattatg
    15061 caagctatga ggaatgtatg gatttcaaat gcattacaat tattatttgg taaagaagta
    15121 tattattcaa aagctaactt tgcatatagt atgttatatc catatactga taattattta
    15181 gacagtacaa atatagataa aaatgataag attttattta ataactggtt agaaaaaagg
    15241 ctcctgggag aacacattaa atctaaggat tatcatgaaa gtaaagtatc tcaaatgata
    15301 gattatattg aaagtgtata ccctagagaa aagtttacag aagtttatga atcgttatta
    15361 ttaatattta aaagtcaagt aaatagttta aaacaacatg gtaaggaaaa tcatttgtgt
    15421 aaagaagatt tattatccat ttctattgaa aaaggaggtt catccgtttt agtagatgga
    15481 tatttaataa gtggattgat gacaaaggaa gaaatagagt tttgtatagg atatggattt
    15541 ttattacaaa tatctgatga tttacaagat ataaaagaag atttaaaata caaccataaa
    15601 actattatta cagagatgtc aaaagagggt actttagata aagttgtaaa taaactaata
    15661 aattttacta ttgagttaat agatagtttt aaaattaata ataaaaataa atctgtaata
    15721 actatgataa agaatgattg cttaatgtta attttatttt ctgtagttta taatgctgaa
    15781 tttttttctg taggatatat aaaagaagta gagaaattta ttccatatac aatagattat
    15841 tcattagaga ttgaagaaaa aataaaagaa aaatttaaaa atatagatgt tttaaataat
    15901 gaaaatgaat ataaagaaat gattgatatt atttgtgcag agtagaaaaa aagggagtgt
    15961 cttagaatag actttttagt ttatgaggca ctctttttgt ataaaatcaa atgtattttc
    16021 atcattttaa caattaaaaa gaacttatcc ctatttgaga aagccctttt taatttaaat
    16081 aaaaatgtca aggttaaact atttaaatgc agtaataatc ccattatcat gtaagttttt
    16141 tatgattgta gctgcgatag ggaatccaaa taatccagct attccaaata gttgagcccc
    16201 aacaaacata cacattaatg ttattaaagg atataggcca atttggtgtc ctactacctt
    16261 tggttctaat atttgtctaa caacggttat aattatgtat agtattaaaa gtcctattgc
    16321 taaattaata tttccattaa tgagtgagat aatcatccaa ggtgtcaaaa tacttcctgt
    16381 acccaagact ggcaaaatat caacaagtgc tatgatgaca gatatagtaa atgcattttc
    16441 aacctttagg atagtaagtc caataagtag ttctatgaat gtcactgata gtagtattgc
    16501 ataggctttt agtagtttta aaagagcatt aatactgcta ttttttatat ttattatcat
    16561 aaattgactt ttttctggaa attgttttaa gataaagttt actatttttt gatagtcaaa
    16621 agtaaagaaa aaagaagcaa ttaaagtaat aataagtttt aacataaatg caggtgtttt
    16681 acttgcaata ctagcaatag cattgagtgc atttgttgaa atagaagcta ctaaagacat
    16741 catagattga cttatattat cccaaccaag tattaatgct aggttaacat taggtgtact
    16801 agcatctatc tttgaaaata aagtatttag cgttggttgt atacttgatt tatatatttc
    16861 aggaagtcta aaaaatacat cacttacact tgcaaatatc ttcacaccaa agctaactaa
    16921 taaaaatata cacaacccat aaaaaattaa aagtattact atagaaataa gtgtacgatt
    16981 taaatttgta ttatttgtaa taagtcttat aataggtctt aagatggatg caatgataaa
    17041 actgattaca aaaggcatta ataatggcaa taagaatttt aatacaatat
//
LOCUS       DAFAZV010000070        16941 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFAZV010000070 DAFAZV010000000
VERSION     DAFAZV010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16941
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.070"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            308..2320
                     /locus_tag="KOU88_003566"
                     /pseudo
     CDS             308..2320
                     /locus_tag="KOU88_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888014.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            2689..3909
                     /locus_tag="KOU88_003567"
     CDS             2689..3909
                     /locus_tag="KOU88_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK3213397.1"
                     /translation="MQQALKLKYQTKELGKDFVIESCNSIKPWLINIRRELHKIPELA
                     LEENLTKQKVISYLKEIGIDYMEFTKHNGIMAYILKESADKTICIRADMDALPIEEEN
                     NIPYKSIHSGKMHACGHDAHTTMLLGACKVLHSIKDKLNVNVKFLFQPAEEGFGGAKF
                     LVEDGCLENPKVDYIFGLHVMPHIETGFIETKYDTLNASVDTIKISIKGKRAHGAYPE
                     NGIDAIVTASQIVTSLQTIISRNLEPNNAAVLTIGKIYGGDAHNVICEDVKLEGTLRT
                     LNSKTRNFMIDKIAKIVGDTASAFGCVGTLHVSDENYPAVINEKELVDTVISNTKELL
                     GEEKFILRPNPSLGGEDFSFYTEHCKGAFFHLGCKNEEKGLISPLHTSSFNIDEDCLP
                     IGVMMHVMNTLYFN"
     gene            3946..5295
                     /locus_tag="KOU88_003568"
     CDS             3946..5295
                     /locus_tag="KOU88_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK3213398.1"
                     /translation="MEKAKKLGLFSMILLGINSIIGSGIFLLPGKVYNLAGQNSMFIY
                     IFATLLVLSILLCFAEVGSMFDKNGGAYLYSKKAFGDFIGFEVGTMSWVIRIISWSTL
                     AVGFATALGSFWPESATEYKGYIAAILVTLLSINSLFGIKSTKIMNNVITIAKLVPLI
                     VFIIVGIFFIKFVNIVPSGNVVNSSMGPAIILVFYAFTGFESFIVASGEMENPKKNLP
                     VALITTIFICAIIYILIQIVCMGILGDRLFENSIPIADASSVFLGNYGKVFISVATLI
                     SIFGINIGSSIVTPKCGSSLAEEGSLPAFIGKTNKYGAPYVAIIISLICCIPLVLTGS
                     FEQLAVMSVIARFAQYIPTCLSVIVLRKRTDVKASFKIPFGPVIPMVAILGSLWLLQQ
                     AWAEDISKPITQNRVLIGLGAMLLIAPLYIFMKKNKEIEHKNKSEDSKLYISREKIQ"
     gene            5409..5971
                     /locus_tag="KOU88_003569"
                     /pseudo
     CDS             5409..5971
                     /locus_tag="KOU88_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901678.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6079..8412)
                     /locus_tag="KOU88_003570"
     CDS             complement(6079..8412)
                     /locus_tag="KOU88_003570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HBK3213399.1"
                     /translation="MRSYLELVPQYAKVHKKKNRTTILCIVIAVCLVTAIFGLADMAI
                     QCQKVQFIKDDGNWHIVLKNLNEEAISEISSRVDIAHYGRGQVIDNGEFKSKEILIQG
                     LDEDLAKQLGLEIIKGRYPVVENETLIDVDAVKSFNLKVGDFIKIKLADGRNKNYKIV
                     GEYSSLSSLRASDKHGLMLSILGTQAIKKSETYDYYYITFKDKVNIRKATSDIKNTFN
                     LSDKQIGKNEKLLSIIGQGDSDYSKPLYLTAGGLFILVLIASIIMIYNSFNMGVIERI
                     KFFGLLRCLGASKLQVKKFVVLESLILSVKAIPLGLLLGCIVTIISSIFLKYVNTELF
                     GSMPILKVSFIGIVFGIIVGFLTVILSAIVPAKKASGVSPLSAIRGNLMFKEILTSGK
                     ASKIANAGSSKIDVSMGINHAFSRKKSFILMTSSFAISIVLFLGFSVFIDFMYQALKP
                     IKPEAAHISIVDADFKSVLTKDDINEISNIKGIKKVYSRMMTDVEATYNNKEATSQLI
                     SYEKNQFDWAKKYLVKGEINEDKLESENIGLVEEGHGFNIGDKIYIKNGNSKKEIEVA
                     GILSSISFDVKDKYIGNIITSENTFTSITDIKDYIIIDTQVDEDAPEDLIQNIRNVLD
                     DNLEVRDKRQGNLEAKNSFYTMAVFVYGFVFIIAIISMFNIINSMNISVTSRINYYGI
                     MRAIGMSNKQLRKMVIVESSTYAVSGCLLGSVLGLILHRYIFVSLVTLKFHIDWQIPF
                     DLLFIIVVTMIIITLLAVRKPIKKICELDIIEVVNAQ"
     gene            complement(8409..9092)
                     /locus_tag="KOU88_003571"
     CDS             complement(8409..9092)
                     /locus_tag="KOU88_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213400.1"
                     /translation="MDILVVNNLCKTYGNGYTKVEALKDVSFTVSKGEFVTVVGESGS
                     GKSTLLNLLGGLDTPTSGKIFVDGKEICSMKEEKQTIFRRRNIGFIFQSYNLIPELTV
                     EQNIIFPLLLDYKKPDTIYLDEVLTILGLKDRKSHLPNQLSGGQQQRVAIGRALITKP
                     SIILADEPTGNLDSKNSSDVISLLKVTAEKYNQTIIMITHNTNIASTADRILQVSDGM
                     LKDLGVNRE"
     gene            complement(9163..10404)
                     /locus_tag="KOU88_003572"
     CDS             complement(9163..10404)
                     /locus_tag="KOU88_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3213401.1"
                     /translation="MKVFSNKDIKIFFLVIISVLLMFIVVGQIVVINITNDYKSALLE
                     HDYNIAGYLNSMGVDKSKIPAVFTTNEDKYTLKGKEILNTARYDFGTDDSFMPSVKLF
                     QGKYIKTMFLYLFVFFTMIIFILYVYFFRQQNKIEEASYKIDSFMNGNINVRLNTYEE
                     GSLSKLFGSIDAMSTSLNTHILKEKQNKEFLKNTISDISHQLKTPLTALMMYNQILQE
                     ESHNSEIVENFVQKSQNELERIESLIQNLLKITKIDSKTIILNKASVNVKKLITKILY
                     SFETRAEKEGKSISIRGLENTNLFCDYEWISEALSNLIKNALDNTKENDKIMIEWVET
                     PITTIISVSDTGNGIHIEDIHHIFKRFYRSKFSKSNQGLGLGLPLVKSIIEQHNGTIT
                     VESNFLQGSTFTLSFLKLTNM"
     gene            complement(10415..11101)
                     /locus_tag="KOU88_003573"
     CDS             complement(10415..11101)
                     /locus_tag="KOU88_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213402.1"
                     /translation="MSSILLVEDDLSLIYGLEYSIQKNGFSVDVARTVEEALQIYKEK
                     NYDLLLLDVSLPDGDGFDICKRVREASNVPIIFLTASDEEVNVVMGLDMGGDDYITKP
                     FKLNELISRIKALLRRYNFTSENVTELKSNNITVKLLENRVFKNEIELELTTAEYKLL
                     CLLMKNKNIVLTRKNILDKLWDGNGSFVDDNTLSVYVRRLRNKIEDNPENPKILLTVR
                     RMGYKWNVIK"
     gene            complement(11339..11683)
                     /locus_tag="KOU88_003574"
     CDS             complement(11339..11683)
                     /locus_tag="KOU88_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213403.1"
                     /translation="MYCLSVVLAIYGIYVFINCTEYIYTMLSTKQLTVTGNEYAIINY
                     YMSNFSQYIIFAILLASMRFVIQKIVHMHFSEIELSGNYSTTVRNISDISLDNDNEMF
                     NRGNIENSILKK"
     gene            complement(12014..14521)
                     /locus_tag="KOU88_003575"
     CDS             complement(12014..14521)
                     /locus_tag="KOU88_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213404.1"
                     /translation="MKLNYIVKKYIMGNKKNTLLIIVSIVISTALFLIMNIISEDATN
                     LMINQAKNEFTLKHAQYINPKDEEIKYIENNTSIDKVGKSMLLGISDIGKGQTLQILS
                     QDKVAEELNDIYTLEKGKLPVAENEIAIDSWYIKQKKIKNPIGKRITLDYRRQGIDQE
                     DLYTGEKEFKITGILNSNPILKAQGTSIGLISNDCAIKNIPTKNKYDQVMFTFKKEKN
                     IQRQSQKLIKNGNLNENNIYFNNELLIAISDSMNLKIPYIIVNIVLALATILLIYNIF
                     YILVSNRIKDFGIFRALGFNPNDIFKIMILEVSIYSIISISIGLILGGIIASLSREYV
                     IGVIYNVNYINSIKNQNYINTYIISILLSLGTIIISVSKPLMLSVKTDPMICIRRNNE
                     KVDIKQNSFINKFMIKLFKDYGNIASKNIQRNKKRTNLSIASMVIIFFLMATIYTKST
                     SNFLSDGVLKYWIQGDYLLHNIDISTIRSNNKGYDKNVLQEIKAIDGVTKVNSYRHKW
                     FNIKIDDKSINKNSDYWKKNKDNIEARSEVKDGIKVYNNSFEFLGIEDTDILEDFLIN
                     GKENIDKFSKQPYLYITKKSSDSLNIKKGDRIKVYFDIIDSKTNNFTKTISQEFIVCG
                     IITTLPVTSQVGAEFGGVISTNQFNKFTGISSYERFDIWTSKLANDKYVESELNKITE
                     KTNKGILIPYKAETAEYEKIDNQKTLIMVLVTGIIVILSLFNCCNTIVTSINSRSREF
                     ALFRGIGISKHEINKIVKLESYIYIIVSFCISIIPILIVRSVIIKPFESINLINWKFI
                     GAIILIVFILVSIIMITTLKTLNKIQNENFMEEIKTL"
     gene            complement(14530..15192)
                     /locus_tag="KOU88_003576"
     CDS             complement(14530..15192)
                     /locus_tag="KOU88_003576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213405.1"
                     /translation="MSILEIKNLNKIYGKSETEVKALSQINLKINSGEFVVIVGKSGS
                     GKSTLLHIMAGLETPTNGDVIIDNINISSLDEKKRSALRKEKLGLIFQSYNLIPVLTV
                     EENIKLPTINIKNKDEAYINELMELLGIKDRRMYLPNQLSGGQQQRVAIARALVNKPS
                     IVFADEPTGNLDTKTESDVLSLLKESQKKYNQTIIMITHNIDITKYADRVIEIEDGFI
                     RE"
     gene            complement(16323..16790)
                     /locus_tag="KOU88_003577"
     CDS             complement(16323..16790)
                     /locus_tag="KOU88_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK3213406.1"
                     /translation="MKFLNVLIVVEDIEKSKKFYYDVLGLKVICDFGENVVLEGNISL
                     QEKKLWLEFINKSDSEVKFNGNDAELYFEEDNFDTFVERLSTMKDIDYVHLAIEHRWG
                     QRAIRFYDLDGHIIEVGETMSSVCRRFLDSGLSMDEVAKRMDVTVEYIESVLE"
BASE COUNT         6071 a         2434 c         1936 g         6500 t
ORIGIN      
        1 ttttaatata attctatatt tacaaaatta tattatcaat agaatttatt aaaataaatt
       61 tttttgggtg tatattataa tttaatcgaa tagaaatgaa aaatatacat acagtttaag
      121 ttttaagcaa caattagggg gatttggtga caagattttt aattataaga aagaaagtgt
      181 cttaatgcaa cttttataaa gtcattatag acactttctt ttttatttga taaatttaaa
      241 ttatcaaaat tatattgctt tatacaacta ttttgttgga aactatttat tatataagga
      301 gaaataaatg aaaaaatcag tagctctggt aaatgatagt agaaaagatt taatagactt
      361 tttagaaaat aatttgaaat tagtttttgg agattctata aatattaata gatacttcat
      421 aaatgaaata aatgataatg atattataaa tgatgatgtg atattagtaa tgtcagtaga
      481 aagattagac aaaattataa ataatatact agataagaaa aaagtgattg tggtaagaag
      541 aacttttagg gaagataaaa tttataatct actatcttta ccacagggta caaacgttct
      601 aatcgtaaat gattctgatg aaactactct agaaactata agtttatttt ataaaattgg
      661 agtgactaat attagaccaa ttccatatat gaatgataat aactataaaa atataaaaat
      721 agctataact ccaggagttc cagaaaaagt acctagcttt atctcagata tatttgattt
      781 aggtcacaga tatatagata tctctacatt tatagaaata ataaatttat tacaaattga
      841 ttcaaaggaa atacaatcta atctagttaa atactcagaa gaaataataa gtttagatac
      901 tggtataaaa gataaatata aggaattatt tttaaaaata gaagaattag atacaatctt
      961 gaatttatca aaagatggta tattatttac ttcaaaagat ggtgaaataa atacatataa
     1021 tagtaaagta aaagatattt tagacataaa tgaggatata tatggaaaat acattgagga
     1081 tatatttgta gatagtttaa aagttttatt gagtgagaaa gagatactag ataaagttgt
     1141 cgtattcaat aggaaatata taaatgtaaa taaaaaaaac atatacaata gagatgaaaa
     1201 aatgggaaca tattatagtt tacaagaaat aacatacata aaaaaattag aacaaaatct
     1261 tactaaaaag ttaagagaaa aaggacaaat agcaaaatat acatttaagg atataaaaac
     1321 aaatagtcct aaaatgtttg aatgtataga tttagctaag aaggtttcta aatctgactt
     1381 aagcatactt atcagaggtg aaagtggaac tggtaaagaa ctcatagctc agtctataca
     1441 taacaactca aatagaaaaa atcaaccctt tatagcagta aattgtgcag ctgttcctga
     1501 aaatttatta gaaagtcagc tattcggata tgacaaagga acttttactg gaggtctaaa
     1561 agatggaaaa caaggattat ttgaacttgc taataatgga acaatattct tagatgaaat
     1621 aggcgatatg ccttgagaat tacaaacaaa actacttaga gttcttcaag aaaagcagat
     1681 aatgcctgtt ggatctcaca atgtaattaa tatagatgtt agaatcatat ctgctacaaa
     1741 taagaattta gaacaaatga ttgataatag ccaatttaga gaggatttat attatcgatt
     1801 aaatacaatt ccaataaata tacctcctct aagagaaaga aaagaagaca tattaattat
     1861 tatggaagat ttaattaata agaaattagt aatcacacca gaagcaaaaa aacttataca
     1921 aaactatatg tggaaaggta atataagaga actccaaaat gttacatcct atttaaacat
     1981 tatgtgtgaa gatattgtat tagagaaaga tttacctcca aacttaaggt cttcagataa
     2041 caaaaataca tcattaaaac taaaatatag taagaatgat atattgaata tattagagat
     2101 actaatttta aataaggaat cagatgttgg tattggtaga ggattaattt taaaagcact
     2161 actcgataag aaccttcaaa ttacagaagg aaaaattaaa aaaatatttg aatatctaaa
     2221 aaaagaagaa cttataattt gtagttcagg aagatatgga agtaaaataa ctcaaaaagg
     2281 agaagatttt tacaataaat taaaatataa aggtctataa aattataatt tatcaaacaa
     2341 agaaatctat tcaggattaa agtactcctt caataggttt ttttattttt caagtaccct
     2401 aaaattataa tttattttgt acataaataa taggaattaa taggaatagg ataatttttt
     2461 tatttcctat tttttttata taaactagca tataaaatat attttcttca aaataatatt
     2521 ttttactgaa aattgaaact atgcaatcat tttttatact atacatatag ataaatgatt
     2581 atatttattc aatattctta taaaaaacaa aattctccat cgaaaattat ggcataataa
     2641 ttgcttatta tattaataaa acaataaaaa gcaattggag gaataaaaat gcaacaggct
     2701 ttgaaattaa aatatcaaac caaagaatta ggaaaagatt ttgtaataga aagttgtaat
     2761 tctataaaac catggcttat aaacataaga agagaattac ataaaattcc agaattagct
     2821 cttgaagaaa atcttactaa acagaaggta atttcttatt taaaagaaat cggaattgat
     2881 tatatggaat ttacaaaaca caatggaatt atggcatata ttttaaaaga aagtgcagat
     2941 aaaacgattt gtataagagc agatatggat gctcttccta ttgaagaaga aaacaacata
     3001 ccttataaat caatacattc tggaaaaatg catgcttgtg gccatgatgc acatacaacc
     3061 atgctacttg gagcatgtaa agttttacat tcaataaaag ataaacttaa tgtaaatgta
     3121 aaattcttat ttcaaccagc agaagaaggt tttggaggag caaaattctt agttgaagat
     3181 ggatgtttag aaaatcctaa ggtcgattat atattcggac ttcatgttat gccacatatc
     3241 gaaacaggat ttatcgaaac aaaatatgat acattaaatg ctagtgtaga cactataaaa
     3301 ataagtatca aaggtaaaag agctcatggt gcatatcctg aaaatggtat tgatgcaata
     3361 gttacagctt cacaaattgt tacatcatta caaactataa taagtagaaa cttagaacca
     3421 aataatgctg ctgttttgac tataggtaaa atatatggtg gtgatgcaca caatgtaata
     3481 tgtgaagatg taaaactaga aggcacttta agaaccttaa atagcaaaac aagaaacttt
     3541 atgattgata aaatagctaa aattgttgga gacactgcat ctgcatttgg ttgtgttggg
     3601 actttacatg taagtgatga aaactatcct gctgttataa atgaaaaaga attagtagat
     3661 acagttatat caaatactaa agaattactt ggagaggaaa aatttatatt gagaccaaac
     3721 ccgtctttag gtggtgaaga cttttctttt tacacagaac attgtaaagg agcattcttc
     3781 catttaggat gtaaaaatga ggaaaagggc ttaatttcac ctcttcatac ctctagcttt
     3841 aatatagatg aagattgttt accaataggt gttatgatgc atgtaatgaa tactttgtat
     3901 tttaattagt acagtaatta ataaaagaat aggagataaa ttaatatgga aaaagctaag
     3961 aaattaggtc tatttagtat gatattatta gggattaata gcataatagg ttcaggtata
     4021 ttcttactac caggtaaagt ttataatcta gcaggtcaaa acagtatgtt tatatacatt
     4081 tttgctacac tcttagttct atcaatactt ttatgttttg cagaagttgg aagcatgttt
     4141 gataagaatg gaggagcata tctatactcc aaaaaagctt ttggagattt tataggattt
     4201 gaagttggta caatgtcttg ggttattaga attatatcat ggtctactct agcagtagga
     4261 tttgcaacag ctttaggttc attttggcca gaatctgcca ctgaatacaa aggttatata
     4321 gctgcaatac tcgtaacact actttcaata aatagcttat ttggaattaa aagcacaaag
     4381 ataatgaata atgtaataac tatagctaaa ttagtaccat taatagtttt tataatagtt
     4441 ggaatattct tcataaaatt tgtaaatatt gttccttcag gaaatgtagt taactctagt
     4501 atgggtccag ccattatatt agtattttac gcatttaccg gctttgaatc atttattgtg
     4561 gcaagtggag aaatggaaaa tcctaaaaaa aatcttccag tcgcattaat aaccacaata
     4621 tttatatgtg caataattta tatattaatt caaattgtct gtatgggtat acttggagat
     4681 agactatttg aaaacagtat tccaattgca gatgcttcaa gtgtattttt aggcaattat
     4741 ggtaaagttt tcatatctgt agcaacatta atatctatat ttggtataaa tataggttca
     4801 tcaatagtaa ctcctaaatg tggttcttct ctagcagaag aaggttctct tcctgcattt
     4861 ataggaaaaa caaataaata tggtgctcca tatgtagcaa taataatatc tttaatttgt
     4921 tgtataccac ttgtgctaac tggaagtttt gaacaacttg cagtaatgag tgtaattgca
     4981 agatttgctc agtacatacc aacttgttta tcagtaatag ttttaagaaa aagaacagat
     5041 gttaaggcct cttttaagat tccatttggt cctgttatac caatggtagc tattttaggt
     5101 agcttatggt tgttacaaca agcttgggca gaagatattt caaaacctat aactcaaaat
     5161 agagttttaa taggattagg ggcaatgttg ttaatagctc ctctatatat atttatgaaa
     5221 aaaaataagg aaatcgagca taaaaataaa tcagaagatt ctaaattata tatttcgaga
     5281 gaaaaaattc aataatattt tacaaactat ttaaaaatta tttttctaat actatagaaa
     5341 taattagaaa tggagatgtt acgtatctaa aagtagttga taacacggat attggtactt
     5401 ttatagatat gggacttaca aaagacatac tagttccttt taaagctaag acttatccat
     5461 tgtttagaga tgaaaaatat ttattctata tatacttgga taaaagcaga agaatagctg
     5521 ctactacaga catagattca tatttagaaa cagaccatac ttacaatgta ggagatgttg
     5581 taaatggagt tgtatatgga ttccaaacca acaactctgc tatgatatgt gttgacaata
     5641 aatatgctgg tgtaatcctt cataatgaat actttacaga attaaaagct ggggatgttc
     5701 ttgaaaattt acatgttata aaaatatacg atgatggtaa attaggactt tctcctagag
     5761 gaaacagaaa agatgaactt gataccttag aaaataagat tttaagctat ttagaaggtt
     5821 cagatggata tatgagattc aatgataaat ctgatcctaa agatatttct atcttattta
     5881 attcaagtaa gaaaatttta aacgtgctct tggagtactt atgaagaaag acttaattta
     5941 tcaagatgaa gatggaactt atctaaagta aattatataa cacaaaaatc gaagtaaatt
     6001 atgaaagata ttttctattt catatttact tcgatttttt atttaaatta ctacctctat
     6061 ttaaattact acttatattt attgtgcatt tactacctct attatgtcta attcacaaat
     6121 ctttttaatt ggttttctta ctgcaagcaa agttattatt atcatagtta ctacaatgat
     6181 aaacagtaaa tcaaaaggta tttgccagtc tatatggaat tttaatgtta ctaaggatac
     6241 aaatatatat ctatgtaata ttaatccaag tacactcccc aataaacagc cacttacagc
     6301 atatgtactt gattctacta ttaccatttt tcttaattgc ttattggaca tgcctattgc
     6361 acgcataata ccatagtaat ttattctact tgtaacgctt atattcatac tgtttatgat
     6421 attaaacata cttataatcg caattataaa tacaaaccca tatacaaaaa ctgccatagt
     6481 gtaaaatgaa tttttagcct ctaagttacc ttgtcgctta tctcgaacct ctaaattatc
     6541 atctagaaca tttcttatat tttggattaa atcttcagga gcatcttcat caacttgagt
     6601 atcaattatt atatagtctt ttatatctgt tatactagta aaagtatttt cagatgttat
     6661 aatatttcca atatatttgt ctttaacatc aaatgaaatt gaagaaagta tacctgctac
     6721 ctctatctct ttcttagaat ttccattttt aatatatatc ttatctccaa tattaaaccc
     6781 atgaccttct tctaccaatc cgatattttc tgactctaat ttatcttcat tgatttcccc
     6841 ttttactaga tactttttgg cccagtcaaa ttgatttttt tcataagaaa ttagctgaga
     6901 tgttgcctcc ttattattgt atgtagcctc tacatccgtc atcattctac tgtatacttt
     6961 ttttattcct ttgatattac ttatttcatt aatatcgtct ttagtaagaa cagacttaaa
     7021 gtcagcgtca acaatagata tatgagcagc ttctggtttt ataggtttaa gtgcctgata
     7081 cataaagtct ataaatacac taaaacctaa aaacaataca atactaatag caaatgaaga
     7141 agtcataagt ataaaagatt tttttcttga aaaggcatga tttattccca tagaaacatc
     7201 aattttagaa cttcctgcgt tagcaatttt acttgctttt ccactagtta aaatttcttt
     7261 gaacattaga ttaccacgta tagcacttag tggagacacc ccagaagctt tttttgctgg
     7321 aacaatagct gataatatta ctgttaaaaa tcctactatt attccaaaca caataccaat
     7381 aaagctaacc tttaaaattg gcatcgaacc aaataactct gtattcacat atttgagaaa
     7441 tatagaggat ataatggtta caatacatcc taataacaat cctagtggaa tagcctttac
     7501 acttagaatt aaactttcta aaacaacaaa ttttttgact tggagttttg atgctcccaa
     7561 gcaacgtaat agtccaaaaa actttattct ctctattaca cccatattaa agctattata
     7621 tatcatgata atacttgcta ttaacacaag tataaaaagt cctcctgctg ttaagtaaag
     7681 tggtttagaa taatcagagt caccttgacc tataatagaa agtaattttt catttttacc
     7741 gatttgttta tcacttaaat tgaaggtatt cttaatatca gaagtagctt ttctaatatt
     7801 aaccttgtct ttaaatgtaa tataataata atcatatgtt tctgattttt tgatagcttg
     7861 tgtacctaat attgaaagca ttaatccatg cttatctgag gctcttaagc ttgataatga
     7921 tgaatattca cctactatct tataattttt atttctacca tctgctaatt ttattttgat
     7981 aaaatctcct acttttagat taaagctttt aactgcatct acatctatta aagtctcatt
     8041 ctccacaaca ggataacgac cttttattat ttctagacct aattgttttg ctaaatcttc
     8101 atctaaacct tgtatcaaaa tctcctttga tttaaactct ccattatcaa tgacttgtcc
     8161 tctaccatag tgagctatat ctactctact acttatttct gatatagctt cttcattaag
     8221 atttttaagt actatgtgcc aatttccatc atcttttata aattgtactt tttgacattg
     8281 tatagccatg tctgctagtc caaaaatagc agtaactaaa catactgcaa tgacaataca
     8341 taaaattgta gttctatttt ttttcttatg tacctttgca tattgtggta ctagttctaa
     8401 atagcttctc attctctatt cacccctagg tctttaagca ttccatcaga aacctgtagt
     8461 atcctatctg ctgtagaagc tatatttgta ttatgagtta tcataataat agtttggtta
     8521 tatttttctg ctgtcacttt taaaagtgaa attacatcac tgctattttt actgtcaaga
     8581 tttcctgttg gctcatctgc caatataatt gatggctttg taatcaatgc tcttccaatt
     8641 gcaacccttt gttgctgacc accagataat tgatttggaa gatgactttt tctatcttta
     8701 agacctaaaa ttgtcaatac ttcatctaga taaatagtgt ctggtttttt gtaatctagt
     8761 agtaaaggaa atattatatt ttgttccaca gttaattcgg gtataagatt atatgattga
     8821 aagataaaac ctatattacg acgtcgaaaa atagtctgtt tttcttcttt cattgaacat
     8881 atttctttac catcaacaaa tatttttcct gaggttggag tatcaagacc tcctaaaaga
     8941 tttaataatg tactcttacc tgagccagat tctccaacta cagtaacaaa ctctcccttt
     9001 gaaactgtaa atgatacatc ttttaatgcc tctacttttg tatatccatt tccatatgtt
     9061 ttacataaat tattaaccac aagaatatcc atttgctcta tctcctttct gatgattaat
     9121 ataagaataa ttcatacacc ttactgtaag atgtatccta tcttacatat tagtaagctt
     9181 taaaaaactt agagtaaatg tacttccttg taaaaaatta ctttctacag ttatggttcc
     9241 attgtgctgt tctatgatag atttaactag tggcaaccct aatccaaggc cttgattact
     9301 ttttgaaaac ttactcctat aaaatctttt aaatatatga tgtatatctt caatatgaat
     9361 tccatttccg gtatcactca ctgaaataat agttgttata ggtgtttcaa cccattctat
     9421 cattatttta tcgttctctt ttgtattatc taatgcattt tttataaggt tgcttaaagc
     9481 ttctgatatc cattcataat cgcaaaacaa gtttgtattt tctagacctc ttatagagat
     9541 actctttcct tctttttctg ctctagtttc aaaactatat aaaattttag taatcaactt
     9601 ttttacgtta acactagctt tgttaagaat tattgtcttt gaatctatct ttgtaatctt
     9661 taacaagttt tgtatcaatg attctatacg ctctaattca ttttgactct tctgcacaaa
     9721 attctcaaca atttcactat tatgactctc ttcctgcaat atttgattat acatcatcaa
     9781 tgctgtaagt ggagttttta gttgatgtga tatatctgaa attgtatttt taagaaattc
     9841 tttattctgc ttttctttca atatatgtgt gtttagagat gttgacatag catctattga
     9901 accaaataac tttgataaac taccttcttc ataagtattt aaccgtacat ttatatttcc
     9961 attcataaat gaatcaattt tataactagc ttcttctatc ttgttctgtt gcctaaaaaa
    10021 atacacatac aatataaaaa taatcatagt aaagaacaca aataaataca aaaacatagt
    10081 ttttatatat ttaccttgaa acaatttcac acttggcata aaactatcat ctgtaccaaa
    10141 gtcatatcta gctgtattta agatttcttt tccttttaaa gtatatttat cttcattagt
    10201 agtaaatact gctggtattt ttgatttatc aacacccata ctatttaagt atccagctat
    10261 attataatca tgttctaaca gtgcactttt ataatcatta gttatattta taactactat
    10321 ttgacctact actataaaca tcaataaaac ggatataatc accaaaaaaa atatttttat
    10381 gtctttatta gaaaatacct tcatattaac accctcactt tataacattc catttgtaac
    10441 ccattcttct aactgttaat agaatttttg gattttcagg attatcttca atcttatttc
    10501 ttaaccttct tacatatact gacagagtat tatcatctac aaaactacca tttccatccc
    10561 ataacttatc caatatattt tttcttgtaa gtacaatatt tttatttttc ataagtaagc
    10621 ataataattt atattctgct gtagtaagct caagctcaat ttcattttta aaaacacgat
    10681 tttcaagtaa tttaacagta atattatttg attttagttc agttacattt tcacttgtaa
    10741 aattataacg tctaagtaaa gcttttattc ttgaaattaa ctcatttaat ttaaaaggtt
    10801 ttgttatgta atcatctcca cccatatcaa gtcccatcac tacatttact tcttcatcag
    10861 aagcagttaa aaatatgatt ggtacattag aagcttctct taccctttta caaatatcaa
    10921 aaccatcacc atcaggtaag gatacatcca aaagcagtaa atcataattt ttttctttat
    10981 aaatttgcaa tgcttcttct actgttcttg ctacatcaac actaaatcca ttcttttgta
    11041 tagaatattc taatccatat atcaaactta aatcatcttc aaccaacaat atactactca
    11101 tctcaatcac ttccattttt ttatttttta ctttatatat attatatacc taacttatta
    11161 tatttttact cttttaaaaa tacaatacct tgaaatcaat gatttaaata ttttaaaatt
    11221 atttttatat gattttatat agttaattta atactttgaa atcttaataa taaaaaaagc
    11281 ttaaaataca ctaagtattc taagctttat tcaatcacat tttatatatt tatattattt
    11341 atttttttaa aatactattt tcaatattgc ctctattaaa catttcatta tcattatcta
    11401 aagagatatc acttatattt ctaacagttg ttgaatagtt accactaagt tctatctcac
    11461 tgaaatgcat atgcactatc ttttgtatta caaatctcat tgatgcaagt aaaatagcaa
    11521 atattatata ctgactaaag ttactcatat aataatttat aatggcatat tcatttcctg
    11581 tgactgttaa ctgttttgta gatagcatag tatatatata ttcagtacaa tttataaata
    11641 catatatacc ataaatagcc aacactacag ataaacaata cattgtgatt gaaatctttg
    11701 atattttttt aaacttacta tctttacaac acttaatatt tgttatttat cataaacaag
    11761 gttattgtat tatcaataat ttttaggtta cacttattat tagtcttgtg ttaaaacgac
    11821 agtagactta agagtagagt tttattaagc caatatttat atttgctata cattgtaccc
    11881 ctattacacc atacatataa cttggataac ttattttatt tttatttcta aattatttaa
    11941 aatcaatatc tacaccatta tcgataattg caattaaatt catataaaac ctctttaatt
    12001 tataggctgt tcactataaa gtctttattt cttccataaa attttcattt tgaattttat
    12061 tcaatgtttt tagtgtagtt atcatgatta tagatactaa aataaatact attaggataa
    12121 tagcccctat aaatttccaa tttattaaat tgatactttc aaaaggtttt attattacac
    12181 ttcttacaat taaaataggt attatagata tacaaaagct tactataata tatatataac
    12241 tttccaattt aacaatttta tttatttcat gttttgatat tcctattcct ctaaatagtg
    12301 caaattccct acttctgcta ttaatactag taactatagt attgcaacag ttaaataaag
    12361 ataatataac tataattcca gttactaata ccataattag tgttttttga ttatcaattt
    12421 tttcatattc agctgtttca gctttgtatg gaattaaaat tcctttattt gttttttctg
    12481 ttattttgtt taactcactt tcaacatatt tatcattggc tagtttactc gtccatatgt
    12541 caaatctttc ataagatgat attcctgtaa acttattaaa ttgatttgtt gatattactc
    12601 cgccaaattc agctcccact tgtgaggtta ctggtaatgt agttataatt ccacatacta
    12661 taaattcttg agatattgtt ttggtaaaat tatttgtttt tgaatctata atatcaaagt
    12721 atacttttat tctatctcct ttttttatat taagcgaatc actggatttc tttgttatat
    12781 acagatatgg ttgtttacta aatttatcta tattttcctt tccatttatc aagaaatcct
    12841 ctagtatatc tgtatcttct attcctaaaa attcaaaaga attattatat accttaattc
    12901 catcttttac ttctgatcta gcttcaatat tatctttatt ttttttccaa taatcagagt
    12961 tcttatttat acttttatca tcaattttta tattaaacca cttatgccta tatgagttta
    13021 cttttgttac accatcaatt gcctttatct cttgtagtac atttttatca taacctttat
    13081 tatttgaacg tatagtactt atatcaatat tatgtaataa ataatctcct tgtatccaat
    13141 attttaatac accatcactt aaaaagttac tagtagactt tgtgtatatt gttgccatta
    13201 agaaaaatat aattaccatt gatgctatag ataaatttgt acgtttctta tttctttgta
    13261 tattttttga tgctatgtta ccatagtctt tgaaaagttt tatcataaat ttatttataa
    13321 aggaattttg ttttatatcc actttttcat tatttcttct tatacaaatc attggatcag
    13381 ttttaactga taacataaga ggttttgaaa ctgatattat tatagttcct aaacttaata
    13441 atatagaaat tatgtatgtg tttatatagt tctggttttt tatagaattt atatagttga
    13501 cattgtatat tactcctata acatactccc ttgataaact agctattatc ccacctaaaa
    13561 ttagacctat agaaatactt ataatagagt atatagatac ttctaaaatc attattttaa
    13621 aaatatcatt tggattaaac cctaaagccc taaatatccc aaaatccttt attctatttg
    13681 atactaatat ataaaaaata ttataaatta ataatatagt tgctagtgct agtactatat
    13741 taactattat ataaggtatt tttaaattca tactgtcaga tatagctatt aataattcat
    13801 tattaaaata aatgttattc tcattcaaat ttccattttt aataagtttt tgtgattgtc
    13861 tctgtatatt tttttccttt ttaaaagtaa acataacttg atcatattta tttttagtag
    13921 gaatattctt gatagcacaa tcgttactta taaggccaat tgatgttcct tgagctttta
    13981 aaataggatt actatttaag ataccagtta ttttaaattc tttttcccca gtatataaat
    14041 cttcttgatc tatcccttgt cttctataat ctaatgttat cctttttcct atagggtttt
    14101 ttatcttttt ttgtttaata taccatgaat ctatagcgat ttcattttca gctactggta
    14161 atttaccttt ttctagtgtg taaatatcat ttagttcttc agcaacttta tcctgagata
    14221 gaatttgtag tgtttgacct ttaccaatat cactaattcc taaaagcatt gattttccaa
    14281 ctttatctat acttgtgtta ttttctatat attttatttc ttcgtctttt ggattgatat
    14341 attgtgcatg ttttaatgta aattcatttt tagcttgatt tatcattaag tttgtcgcat
    14401 cttcacttat tatattcata attaaaaaca acgctgttga aattacaata cttacaatta
    14461 ttaataatgt atttttctta tttcccatta tatatttttt tacaatataa ttaagtttca
    14521 taaatctacc tactctctta taaatccatc ttctatttct ataactctat cagcatattt
    14581 tgttatatct atattatgtg ttatcattat tattgtctga ttatattttt tttgagattc
    14641 ttttaataaa cttaatacat ctgactctgt ctttgtgtct aaatttccag taggttcatc
    14701 agcaaataca attgatggtt tatttacaag agcccttgct attgctactc tttgttgttg
    14761 cccacctgat aattgatttg gcaaatacat tcttctatct tttattccta gtaactccat
    14821 caattcatta atataagctt catctttatt ttttatattt atagttggta gttttatatt
    14881 ttcttcaaca gttaaaactg gaatcaaatt atatgattga aatattaatc ccaacttttc
    14941 tttacgtaat gcagatcttt tcttttcatc aagagatgat atatttatat tatcaataat
    15001 cacatcacca tttgttggag tttcaagtcc tgccattatg tgtagtaaag tacttttccc
    15061 acttccactt ttacctacta tcacaacaaa ttctccacta tttattttta gatttatttg
    15121 acttaacgct ttcacctctg tttccgattt accatatatt ttatttaggt tttttatctc
    15181 taaaatactc ataatttact ccttgtctta catgttattt acacttataa attcgatttt
    15241 tgctatggat tttgcaatct ctatctatac ttattgatat gtagcaacag aaactatttt
    15301 tataattttc aaaaaattct tccgcctatt cactccatat agtgccttta gttatcatac
    15361 catatcttat aattgaattt tatttcttat atctctttta ccaacctttt tatttaggaa
    15421 aagttcttca ccatgaaatt gtacagtata tacctatttc tttgattata taattaagct
    15481 ttttatttag taacctattt tctacatcct aacttatatt tcctgtttcc tcattttcat
    15541 atttataaca atagttacaa tctaaattac tacttttagt tacccagact ttactttaca
    15601 tgctttgcct ctaaactgct gatgttaata tcttcttaat tttttcacac ctatcttcaa
    15661 atataaaatc tttatctaaa agattattgt attcagctag acataaccaa caaaatgatt
    15721 tcattaaata ttctttacat tcattattac ataactttaa gttgaaaaac tcattatatc
    15781 caaaattcgt tgatacccat attattaata taacttacaa tatctttttg aatatctaaa
    15841 aaaatacttt tataacttat tttatatatc atacactata ttattgcttt cataatctat
    15901 aaaggtttca tatgatacaa acttctaaga tgggattttt ggtctttaat aacgattata
    15961 ataatattta tttatatttc tgatttaaac attattttac ttgaaatgtt tattaaataa
    16021 atgaattaaa actaaacttt cattatattt ttaatttatt caattaaatt ttagcatagt
    16081 tatataaaat agtatatata attatacaag ataatagtaa atataactat cttttatata
    16141 ttttttctaa atctaaactt tcgtataaat atataagaaa tatcataata tttttaaaaa
    16201 ctcaaataaa gctaaacaag tattatattc tttattttag aaaaataaaa actgtaagca
    16261 aatttgtttt cacacaagtt tacttacagc cttcacctca attttacttt aatataatcc
    16321 atctattcta aaactgattc aatatattcg acagttacat ccattctttt agctacttca
    16381 tccattgaaa gaccactatc taaaaaacgt ctacacacag atgacatagt ttctccaacc
    16441 tcaataatat gcccatctaa atcataaaat ctaattgctc tttgacccca cctatgctct
    16501 atagctagat gaacataatc tatatctttc attgtactca atctttcaac aaaagtatca
    16561 aaattatctt cctcaaaata taactcagca tcatttccat tgaacttaac ttcactgtca
    16621 ctcttattaa taaattctaa ccaaagcttt ttttcttgta atgatatatt accttctaat
    16681 acaacatttt ctccaaaatc acagattacc tttaacccca aaacatcata ataaaacttt
    16741 tttgatttct caatatcttc aactactatt aaaacattta aaaacttcat attacctcct
    16801 taatatacac atactttatt tataatatat aattagaatt aaactataaa ggtttcaata
    16861 aggtctagta taaagaaaaa aattataagt cttattgaaa tagttaagtt aatttaattt
    16921 tatcatataa tataaatttt a
//
LOCUS       DAFAZV010000071        16218 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFAZV010000071 DAFAZV010000000
VERSION     DAFAZV010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 16218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16218
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.071"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..237
                     /gene="tuf"
                     /locus_tag="KOU88_003578"
     CDS             <1..237
                     /gene="tuf"
                     /locus_tag="KOU88_003578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003452162.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBK3213407.1"
                     /translation="GGRHTPFFDGYRPQFYFRTTDVTGACKLPEGIEMVMPGDNVTME
                     VDLINSIVVEEGLRFSIREGGRTVASGVVATIIE"
     gene            487..636
                     /gene="rpmG"
                     /locus_tag="KOU88_003579"
     CDS             487..636
                     /gene="rpmG"
                     /locus_tag="KOU88_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004402360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBK3213408.1"
                     /translation="MRVKVTLACTECKQRNYNTTKNKKNNPDRIELQKYCRFCKKHTT
                     HKETK"
     gene            662..883
                     /gene="secE"
                     /locus_tag="KOU88_003580"
     CDS             662..883
                     /gene="secE"
                     /locus_tag="KOU88_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBK3213409.1"
                     /translation="MAAQKNDGAKTKKRFSLFGYLKETKQELKRVTWPTKKELFKNTS
                     IVLTVVISCTILVWGIDTILSGALALLLK"
     gene            903..1445
                     /gene="nusG"
                     /locus_tag="KOU88_003581"
     CDS             903..1445
                     /gene="nusG"
                     /locus_tag="KOU88_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination factor
                     NusG"
                     /protein_id="HBK3213410.1"
                     /translation="MSELQEASWYVVHTYSGHENKVKATIEKAVKTRGMEDCIRQVVV
                     PTEEVVETTKTGKEKTRQRKVYPSYVLVKMIITDESWYVVRNTKGVTGFVGPGSKPVP
                     LSEDEVKAMGIDTTDPKVVNSDIDFEIGDTVKVSQGPFSGQIGNIEEIDLENREVKVC
                     INAFGKRTLFVIELEGIEKI"
     gene            1484..1909
                     /gene="rplK"
                     /locus_tag="KOU88_003582"
     CDS             1484..1909
                     /gene="rplK"
                     /locus_tag="KOU88_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012158357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBK3213411.1"
                     /translation="MAKKVIGQIKLQIPAGKATPAPPVGPALGQHGVNIMGFTKEFNA
                     KTADQAGMIIPVVITVYQDRSFSFITKTPPAAVLIKKALNLKSGSGEPNKKKVAKMTS
                     AQVREIAELKMPDLNAASVEAAMSMIAGTARSMGVVIED"
     gene            1980..2678
                     /gene="rplA"
                     /locus_tag="KOU88_003583"
     CDS             1980..2678
                     /gene="rplA"
                     /locus_tag="KOU88_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBK3213412.1"
                     /translation="MAKKGKRYAGALQKVDRTKFYDASEALTLVSDIAGAKFDETVEA
                     HIKLGVDSRHADQQVRGAVVLPHGTGKTKRVLVFAKGEKAKEAEQAGADFVGAEELVQ
                     KIQGENWFDFDIVVATPDMMGVVGRLGRVLGPKGLMPNPKSGTVTFDVAKAIDEIKAG
                     KVEYRLDKTNIIHVPVGKVSFGGEKLTENFTALMDAIIKAKPAAAKGQYLRSITVASS
                     MGPGVKINPARTAE"
     misc_feature    2730..2858
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            2901..3407
                     /locus_tag="KOU88_003584"
     CDS             2901..3407
                     /locus_tag="KOU88_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBK3213413.1"
                     /translation="MRKAIEIKSEVVSEIVEKLQKSSAAVVVDYKGLTVEEVTELRKQ
                     MREAGVDYKVYKNTLVRRAAKEVGIEQFNDELLVGTNAIAFGYDDPVAPARILKGFMD
                     SHPKMKLKMGIVEGAFYDESKIVEMANIPSREVLIAKLLGSLKAPVSNFAYLIDAIAK
                     KAEGQEEA"
     gene            3465..3830
                     /gene="rplL"
                     /locus_tag="KOU88_003585"
     CDS             3465..3830
                     /gene="rplL"
                     /locus_tag="KOU88_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBK3213414.1"
                     /translation="MTIEQILEAIENMKVLELNELVKAAEEKFGVSASAPVMVAGAAA
                     GGPAAEEKTEFDVVLTDVGSSKVGVIKAVREITGLGLKEAKEVVDNAPKTVKEGASKE
                     EADQIKEKLEAAGAKVEVK"
     gene            4222..5010
                     /locus_tag="KOU88_003586"
     CDS             4222..5010
                     /locus_tag="KOU88_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK3213415.1"
                     /translation="MEKLQGKIAVVTAATKGIGLASAEILAKNGATVYLAARSEELAN
                     EVINKISAEGGCAKFVYFNAREEETFTSMIEEVVKKEGKIDILVNNFGSTNPSLDKDL
                     VTGDTDNFFDTVNTNLKSVYLPCKAAIPHMIKNGKGSIVNISSIGSVLPDLSRIAYCV
                     SKAAINSLTQNIATQYAKDNVRCNAVLPGLIATKAALDNMSPEFIKEFLKHVPLNRIG
                     EPDDIAKAVLFYASDDSSFITGDLLEVAGGFGLPTPQFADNILG"
     gene            5481..9197
                     /gene="rpoB"
                     /locus_tag="KOU88_003587"
     CDS             5481..9197
                     /gene="rpoB"
                     /locus_tag="KOU88_003587"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBK3213416.1"
                     /translation="MPHPVTIGKRTRMSFSKIKEIADVPNLIEIQVDSYEWFLKEGLK
                     EVFDDISPIEDYTGNLILEFVDYSLDDKPKYDIEECKERDATYCAPLKVKVRLINKET
                     GEIKEQEVFMGDFPLMTERGTFVINGAERVIVSQLVRSPGVYYAEERDKTGKRLISST
                     VIPNRGAWLEYETDSNDVISVRVDRTRKQPVTVLLRALGIGTDAEIIDLLGEDERLSA
                     TLEKDNTKTVEEGLVEIYKKLRPGEPPTVESASSLLNALFFDPKRYDLAKVGRYKFNK
                     KLALCYRIMNKISAEDIINPETGEVFVKAGEKISYDLAKAIQNAGINVVNLLMDDDKK
                     VRVIGNNFVDIKSHIDFDIDDLNIKEKVHYPTLKEILDGYSDEEEIKEAIKSRIKELI
                     PKHILLDDIIASISYEFNIFYNIGNIDDIDHLGNRRIRSVGELLQNQVRIGLSRMERV
                     IKERMTVQDMEAITPQALVNIRPVSAAIKEFFGSSQLSQFMDQTNPLSELTHKRRLSA
                     LGPGGLSRERAGFEVRDVHHSHYGRMCPIETPEGPNIGLINSLGTYAKINEFGFIESP
                     YRKFDKETSTVTDEIHYLTADEEDLFVRAQANEPLTEDGKFVNHRVVCRTVNGAVEMV
                     PESRVDYMDISPKQVVSVATAMIPFLENDDANRALMGANMQRQAVPLVRREAPIIGTG
                     IEYRAAKDSGAVVVARNSGIAERVTADEIIIKREDGNRDRYNLLKFKRSNSGTCINQT
                     PIINKGDQIIKGDVIADGPATDLGEVALGRNCLIAFMTWEGYNYEDAILINERLVKED
                     RLSTIHIEEYECEARDTKLGPEEITRDIPNVGDSAIKNLDDRGIIRIGAEVDSGDILV
                     GKVTPKGETELTAEERLLRAIFGEKAREVRDTSLKVPHGESGIIVDVKVFTRENGDDL
                     SPGVNELVRCYIAKKRKIKVGDKMAGRHGNKGVISRVLPEEDMPFMENGTPLDIILNP
                     QGIPSRMNIGQVLEVHLGLAAKTLGWYVATSVFDGANEYDIMDALEEAGYPRDGKLTL
                     YDGRTGESFDNRITVGYMYYLKLHHLVDEKLHARSTGPYSLVTQQPLGGKAQFGGQRF
                     GEMEVWALEAYGAAHILQEILTVKSDDVVGRVRTYEAIVKGENIPEPGIPESFKVLIK
                     ELQSLCLDVKVLTDEDQEIEVRESVDEDDTIGEFELDVVNHMGEVEESNIIEEIEDDF
                     AENAEDEDIENLEEFTEDDLFEEEIDFDSDDFDM"
     gene            9239..12724
                     /gene="rpoC"
                     /locus_tag="KOU88_003588"
     CDS             9239..12724
                     /gene="rpoC"
                     /locus_tag="KOU88_003588"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBK3213417.1"
                     /translation="MFELNNFESIKIALASPEKIRQWSRGEVKKPETINYRTLKPEKD
                     GLFCERIFGPQKDWECHCGKYRRVRYKGVVCDRCGVEVTKSKVRRERMGHIELAAPMS
                     HIWYFKGIPSRMGLLLDMSPRSLEKILYFASYVVVDPGETGLNEKQLLTEKEYRTALE
                     KYGYTFTVGMGAEAVKTLLQNIDLEQQSKDLRAELKDSTGQKKVRTIRRLEVVEAFKK
                     SGNKPEWMILDAIPVIPPDLRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLELGA
                     PDIIVRNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSDMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPELKFYQCGLPKKMALELFKPFVMDKLVKEGYAHNIKSAKSIVEK
                     VKPEVWDVLEDVIKSHPVLLNRAPTLHRLGIQAFEPILVEGKAIKLHPLVCTAYNADF
                     DGDQMAVHVPLSVEAQAEARFLMLSVNNILAPKDGSPITTPSQDMVLGCYYLTIEAQD
                     GAKGTGMVFKDFNELLLAYYNKSVHLHALVKLKVTLEDGRSSLVESTVGRFIFNENIP
                     QDLGFVDRKENPFALEVDFLADKKSLGKIIDKCFRKHGNTETAELLDYIKALGFKYST
                     LGGITVAVDDMSVPEEKKVFIAEAEAKVDKYEKAYRRGLISDEERYEKVIETWTETTD
                     KVTDALMGGLDRLNNIYIMAHSGARGSKNQIRQLAGMRGLMANASGKTVEIPVKSNFR
                     EGLSVLEYFTSSHGARKGLADTAIRTAESGYLTRRLVDVSQDVIVREIDCGTEDTTEI
                     YAIKEGNEVIEEIYDRIVGRYTIDPILNPETGEVIVEADSMIQEDEAETIVALGIEKI
                     RIRTVLNCKTNHGVCSKCYGRNLATGKEVNIGEAVGIIAAQSIGEPGTQLTMRTFHTG
                     GVAGADITQGLPRVEELFEARKPKGLAVITEVSGRVEIDETGKRKEVNVIPEEGETQT
                     YVIPYGSRLKVKQGQMLEAGDPLTQGFINPHDIVRVNGVKGVQEYIVKEVQRVYRLQG
                     VDVNDKHIEVIVRQMLSKVKVEDPGDTDLLPGGYEDVLTFNECNKDAIDKGLRPAVAK
                     RVLLGITKASLATDSFLSAASFQETTRVLTEAAIKGKEDHLIGLKENVILGKLIPAGT
                     GMKKYRNIAVEKIED"
     gene            13013..13435
                     /gene="rpsL"
                     /locus_tag="KOU88_003589"
     CDS             13013..13435
                     /gene="rpsL"
                     /locus_tag="KOU88_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBK3213418.1"
                     /translation="MPTINQLVRKSRKALEKKSTAPALQKGYNSLNKKVTDASAPQKR
                     GVCTSVKTVTPKKPNSALRKVARVRLTNGIEVSAYIPGEGHNLQEHSVVLIRGGRVKD
                     LPGVRYHILRGTLDTAGVDKRRQSRSKYGAKRPKEAKK"
     gene            13559..14029
                     /gene="rpsG"
                     /locus_tag="KOU88_003590"
     CDS             13559..14029
                     /gene="rpsG"
                     /locus_tag="KOU88_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBK3213419.1"
                     /translation="MPRKGNIPKREVLPDPMYGSKVVTKLINNLMVDGKKGKSQRIVY
                     DAFAIVAEKTGEEALEVFNKAMDNIMPVLEVKARRVGGANYQVPIEVRPERRQTLGLR
                     WLVKYTRARGEKGMVEKLAKEIMDAANNTGASVKKKEDTHKMAEANKAFAHYRW"
     gene            14078..16144
                     /gene="fusA"
                     /locus_tag="KOU88_003591"
     CDS             14078..16144
                     /gene="fusA"
                     /locus_tag="KOU88_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBK3213420.1"
                     /translation="MARKFPLERTRNIGIMAHIDAGKTTTTERILFYTGQTHKIGETH
                     EGASQMDWMEQEKERGITITSAATTASWKDHRINIIDTPGHVDFTVEVERSLRVLDGS
                     VAVFCAKGGVEPQSENVWRQAETYGVPRIAFVNKMDILGADFYNVVSMMKSRLNSNAV
                     PMQLPIGKEDSFIGIIDLLKMDAVIYKDDLGVEMEETDIPEDMKELAAEWREKLVESV
                     AETDEELMMKYLEGEELTIDELKVAIRKATIACEMNPVFCGTAYRNKGVQLVIDAVLD
                     YLPAPTDIPAIKGILADGEEAERHSSDEEPFSALAFKIMTDPFVGKLAFFRVYSGTLE
                     SGSYVLNATKNKRERIGRILQMHANTREEITKVYAGDIAAAVGLKDTTTGDTLCDPAN
                     PIILESMEFPEPVISVAIEPSSKAAQEKMGIALQKLAEEDPTFTVKTDQETGQTIISG
                     MGELHLEIIVDRLLREFKVEAKVGAPQVAYRETITQPVDVEYKYSKQSGGRGQYGHVK
                     IRVAPQEPGEGYKFTNKTVGGSVPKEYVGPVDMGIQGAMQSGIVAGYPVVDVAVELYD
                     GSYHEVDSSEMAFKMAGSMAFKDAMKKGNAVLLEPYFKVEVVTPEDYMGDVMGDLNSR
                     RGLIQGMEARSGAQVINAFVPLSEMFGYSTDLRSSTQGRATYTMIFDHYEQVPASVAK
                     KIAEGK"
BASE COUNT         6347 a         2020 c         3308 g         4543 t
ORIGIN      
        1 ggtggaagac atacaccatt ctttgatgga tatagaccac aattctattt cagaacaaca
       61 gacgtaacag gagcttgtaa gttaccagaa ggaatagaga tggtaatgcc tggagataac
      121 gtaacaatgg aagtagactt aataaactca atagttgtag aagagggatt aagattctca
      181 ataagagaag gtggaagaac agtagcttca ggagttgttg ctacaataat agagtaattc
      241 tttactaaac tgatggatta aaaggaataa caaaaagagg ggttatgctc ctcttttttt
      301 aacatagaaa tacaaaaaca ttgacacagc ataggatttt gtgataactt atacaaggta
      361 atgattatag gaagttaata atatcttgaa tactgtagat ttttaataaa tacatatttt
      421 aaagatatta tattcacata tattaacaat atatattatt gtattacaaa gttggaggtg
      481 tatcagatga gagttaaagt aactttagca tgtacagagt gtaagcaaag aaactacaac
      541 actactaaga ataagaaaaa caatccagac agaatagaat tacaaaaata ttgtagattc
      601 tgtaaaaagc atacaactca taaagaaaca aaatagtttt ttataaggat gtgagtatgg
      661 aatggctgcc caaaaaaatg acggtgcaaa aactaaaaaa aggtttagtt tgtttggata
      721 cttaaaagaa actaaacaag aattaaaaag agttacatgg ccgacaaaaa aggaactgtt
      781 taaaaacaca agtatagttt taactgtagt tatttcatgc actatattag tatggggtat
      841 agacactata ttatctggtg cactagcgtt attactaaaa tagacgaaaa gaggtaagtt
      901 aaatgtcaga attacaagaa gcaagttggt atgtagttca tacctattcg ggacatgaaa
      961 ataaagttaa agctacaatt gagaaagcag ttaaaacaag aggtatggaa gactgcataa
     1021 gacaagtagt tgttccaaca gaagaagtag tggaaactac taaaactgga aaagaaaaaa
     1081 ctagacaacg taaagtttat ccaagttatg ttttggttaa aatgataata actgatgaat
     1141 cttggtatgt agtaagaaat actaagggag ttacaggttt cgttggacct ggttcaaaac
     1201 cagtgccatt aagtgaagac gaagtcaaag ctatggggat agacacaaca gaccctaaag
     1261 tagtaaatag cgatattgat tttgaaatag gagatacagt aaaagtatct caaggaccat
     1321 ttagtggaca aataggtaac atagaagaaa ttgacttaga aaatagagaa gtcaaagtat
     1381 gcataaatgc atttggtaaa aggactctat ttgtaataga gcttgaaggt atagaaaaaa
     1441 tctaatacta tattatagaa aaatctgagg aggtgcgctc aaaatggcta aaaaagttat
     1501 aggtcaaata aaattacaaa tacctgcagg aaaggctact ccagcgccac cagttggacc
     1561 agcattagga caacatggtg ttaatataat gggattcaca aaagaattta atgctaaaac
     1621 tgcagatcaa gctggaatga taataccagt tgttataact gtatatcaag atagatcatt
     1681 cagttttata acaaaaactc caccagctgc agttttaatt aaaaaagcat taaacttaaa
     1741 atcaggttct ggagaaccaa acaagaaaaa agttgctaaa atgacttcag ctcaagtaag
     1801 agaaatagct gaattaaaga tgcctgactt aaatgctgca tcagtagaag ctgctatgag
     1861 tatgatagct ggtactgcta gaagcatggg tgttgtaatc gaagactaat taaaagatac
     1921 actttttttt ataaagtggg aggctagaag ccgaaattaa ccacgaggag gaaaataaaa
     1981 tggctaaaaa aggtaaaaga tatgcaggtg cattacaaaa agtagataga actaaatttt
     2041 atgatgcatc agaagcatta acattagttt cagatatagc tggagctaaa tttgatgaga
     2101 cagtagaagc acacattaaa ttaggtgttg actcaagaca tgctgaccaa caagtaagag
     2161 gtgcagttgt attacctcat ggaactggta aaacaaaaag agttttagtt tttgctaaag
     2221 gtgaaaaagc taaagaagct gaacaagctg gtgctgactt tgtaggagct gaagaattag
     2281 ttcaaaaaat acaaggtgaa aactggtttg actttgatat agtagttgct actccagata
     2341 tgatgggtgt agtaggtaga ttaggtagag tattaggacc taaaggttta atgccaaacc
     2401 ctaaatcagg aacagttaca tttgatgtag ctaaagctat agatgaaata aaagctggta
     2461 aagttgaata cagattagac aaaactaaca taatacacgt tccagtagga aaagtatcat
     2521 ttggtggaga aaaattaact gaaaacttta ctgcattaat ggatgctata ataaaagcta
     2581 aaccagctgc tgctaaagga caatatttaa gaagtataac agtagcttct tcaatgggac
     2641 ctggagttaa aataaaccca gcaagaacag ctgaataata aaactgttga cacaggttga
     2701 caaaaatgtt attatatcac ttgtcaatgt aaaaaagaat agatttgccg tagatagtgg
     2761 gtgcgagagc ttaatatccc gccgaggttt tagataaatt gagattacta aagcttttga
     2821 tgtctacttt tggcaacaaa agctttttat aatgttgcgg taaatactaa gcctatttgg
     2881 tgaaggaggt gcacatctat atgagaaaag ctatagaaat taaatcagaa gttgtttctg
     2941 agatagttga aaagttacaa aaatcttctg ctgctgttgt tgtagattac aaaggattaa
     3001 cagttgaaga agtaactgag ttaagaaaac aaatgagaga agctggtgta gattacaaag
     3061 tatacaaaaa tactttagtt agaagagcag ctaaagaagt tggtatagag caatttaatg
     3121 atgaattatt agttggaact aatgccatag catttggata tgatgatcca gttgctccag
     3181 ctagaatatt aaaaggattc atggattctc atccaaaaat gaaattaaag atgggtattg
     3241 tggaaggtgc attctatgat gaatctaaga ttgttgaaat ggctaacata ccatcaagag
     3301 aagttcttat cgctaaatta cttggtagct taaaagctcc agtatcaaac ttcgcatact
     3361 taatagatgc aatagcgaaa aaggcagaag gtcaagaaga agcttaattg cttaactaaa
     3421 aaattataaa tattaatttg aaataaaatt cggaggtgct aaaaatgaca atagaacaaa
     3481 tattagaagc tatagaaaat atgaaagttt tagaattaaa tgaattagtt aaagctgctg
     3541 aagaaaaatt cggtgtatca gcttcagctc cagtaatggt agctggtgca gctgctggtg
     3601 gaccagctgc tgaagaaaaa actgagtttg atgtagtatt aactgacgtt ggttcttcaa
     3661 aagttggagt tataaaagca gttagagaaa taacaggatt aggattaaaa gaagctaaag
     3721 aagtagttga caatgctcct aagacagtta aagaaggagc ttctaaagaa gaagctgatc
     3781 aaataaaaga gaaattagaa gctgctggag ctaaagtaga agttaagtag tttctttaaa
     3841 aagataccca ttgggtatct ttttttattt ataaaaaact ataaagaaag tatttggaat
     3901 tataaagaaa gtatttttat aaaataaaaa aaatttatat aatagtacta aattaagggt
     3961 atcatatatg gtgtaatggt attttaattt aacattatta tcaaattaaa atataaacaa
     4021 ttgttgtaat gtctgtatat aaagtatata attaaactaa aatgtaaaat tttacatttt
     4081 agtttaaaaa aatacacgag tgttttataa ataaaatgta ataaataatt aattaacaaa
     4141 tataaatttt aaaataagtt agatatttag aaaaatcgaa atttgtagga tttaaaggac
     4201 atattcaagg aggagttaat aatggaaaaa ttacaaggaa aaattgcagt agttactgca
     4261 gcaacaaaag gtattggatt agcatcagca gagatattag caaaaaatgg agcaactgtg
     4321 tacttagcag ctcgttcaga agaattagct aatgaagtta taaataaaat aagtgcagaa
     4381 ggtggttgtg ctaagtttgt ttactttaat gctcgtgagg aagagacctt tacctcaatg
     4441 atagaagagg tagttaaaaa agaaggtaag atagatatac ttgtaaacaa ttttggttca
     4501 acaaaccctt ctcttgacaa agaccttgta actggagata cagataattt ctttgacaca
     4561 gtaaatacta atttaaaaag tgtgtattta ccatgtaaag cagcaattcc tcatatgata
     4621 aagaatggaa aaggaagtat agtaaatata tcaagtatag gttcagtatt acctgattta
     4681 tctagaatag cttactgtgt atcaaaagca gcaatcaact cattaactca aaacatagct
     4741 acacaatatg ctaaagacaa tgttagatgt aatgctgtac ttccagggct tattgcaact
     4801 aaagcagcat tagacaatat gtctccagag ttcataaaag aatttttaaa gcatgttcct
     4861 ttaaatcgta taggggaacc agatgatata gcaaaagctg ttctattcta tgctagtgat
     4921 gactcatcat ttataacagg ggatttactt gaagttgcag gaggatttgg tttacctact
     4981 ccacaatttg cagataatat attaggataa ttaaattact aatatgcaat gaaagcttat
     5041 gcattagtta tagtagaaat gatattttta taaaggccat agatataatt tatattggaa
     5101 aggtttgagg ttcaaaattc caagttaaat ttatttatgg tctttatttt gtatatttta
     5161 ataaattgta tatatttgta taaatgtaat tatttacaat cattttaata tggaattata
     5221 attaaatagg ggggatggta cttgtataaa attttttata gaaaattaga cctataaatg
     5281 aaaaatatgg attttatatt ggaaaattgt acataataca taatatatgc ttaaaataat
     5341 ttacaaaaaa tcaaaaataa tgcatagttt acatataaga taaaaaatat attgaaaaat
     5401 acttgacatt atgctaaaat tattagatgc gttagaatga actattgttt tatttttaat
     5461 tattgagagg tgaaaagtga atgccacatc ctgtcacgat aggtaaaaga actagaatga
     5521 gcttttctaa aattaaggaa atagctgatg tgccaaatct tatagaaatt caagtagatt
     5581 cctatgagtg gtttttaaaa gaaggtttaa aagaagtgtt tgatgatatt tcaccaatag
     5641 aagattatac tggtaatctt atattggaat ttgtcgacta ttctctagat gataaaccaa
     5701 agtacgatat agaagagtgt aaagagagag atgctacata ttgtgcacct ctaaaggtta
     5761 aggtaagact tataaataaa gaaacaggtg agataaaaga acaagaagtg tttatgggtg
     5821 acttcccttt aatgacagaa agaggaactt tcgttataaa tggagcagaa agagttatag
     5881 taagtcaatt agttagatct cctggtgttt actatgcgga agaaagagat aaaacaggta
     5941 agagattgat ttcatctact gtaattccta atagaggagc atggttagaa tatgaaacag
     6001 attctaatga tgtaatatct gtaagagttg atagaacaag aaaacaacca gttacagttt
     6061 tacttagagc tttaggaata ggaacagatg cagagataat tgacctttta ggagaagatg
     6121 agagattatc tgctacatta gaaaaagata atactaagac agtagaagaa ggtcttgtag
     6181 agatatacaa aaaattaaga ccaggtgaac ctcctactgt agaaagtgca tcatctttat
     6241 taaatgcttt attctttgac ccaaaaagat atgacctagc aaaagttggt agatataaat
     6301 tcaataagaa acttgcttta tgttatagaa taatgaataa aatttcagca gaagacataa
     6361 taaatccaga aactggagaa gtatttgtaa aagctggaga aaaaataagc tatgatttgg
     6421 ctaaagccat acaaaatgca ggtataaatg tagtaaatct actaatggat gatgataaaa
     6481 aagttagagt tataggaaat aattttgtgg atattaagtc tcacattgat tttgacatag
     6541 atgatttaaa cataaaagaa aaagtacatt atccaacttt aaaagaaatt ttagatggat
     6601 atagtgatga agaagaaata aaagaggcta taaaatcaag aattaaagaa cttataccaa
     6661 aacatatatt attagatgat ataatagctt caataagtta tgagttcaat atattctata
     6721 atataggaaa tattgatgat atagatcacc taggaaacag aagaataaga tctgtaggtg
     6781 aattgttaca aaatcaagtt agaattggtc tttcaagaat ggaaagagtt ataaaagaaa
     6841 gaatgacggt tcaagatatg gaagctataa cgcctcaagc gttagttaac ataagaccag
     6901 tttcagctgc aataaaagaa ttttttggta gttctcagtt atctcagttc atggatcaaa
     6961 caaatcctct atctgagtta acgcataaga gaagattatc agcccttggg cctggaggtc
     7021 tttcaagaga aagagctgga ttcgaagtgc gtgacgttca ccattcacac tatggtagaa
     7081 tgtgtccaat agagactcca gagggaccaa atatcggtct tataaactct ctaggaactt
     7141 atgcaaaaat aaatgaattt ggatttatag aatcaccata tagaaaattt gataaagaaa
     7201 catcaacagt tactgatgaa atacattatt taactgctga cgaagaagat ttattcgtaa
     7261 gagctcaggc aaatgagcca ttaacagaag atggtaaatt cgtaaaccat agagttgttt
     7321 gtagaactgt aaatggtgct gttgaaatgg ttcctgaaag tagagtagat tacatggata
     7381 tatctcctaa gcaggttgta tctgttgcca ctgctatgat acctttctta gaaaatgatg
     7441 atgccaaccg tgcccttatg ggagcgaaca tgcagcgtca ggcagtgcct ctagttagaa
     7501 gagaagcacc aattatagga actggtatag aatacagagc agcaaaagac tctggagcag
     7561 ttgttgttgc tagaaattct ggtatagcag aaagagtaac agcagatgaa ataattataa
     7621 aaagagaaga tggaaacaga gatagatata atctacttaa gtttaaacgt tcaaactcag
     7681 gtacttgtat aaatcaaaca cctataataa ataagggtga ccagataata aaaggtgatg
     7741 ttatagcaga tggtccagca actgatttag gagaagttgc acttggaaga aactgtctta
     7801 tagcattcat gacttgggaa ggttataact acgaggatgc tatattaata aatgaaagat
     7861 tagttaaaga agatagatta tcaacaattc atatagaaga atatgaatgt gaagctagag
     7921 atacaaaact agggccagag gaaataacta gagatatacc taatgttgga gatagtgcaa
     7981 ttaagaactt agatgacaga ggtataataa gaataggtgc agaagtagac tcaggtgata
     8041 tattagttgg taaagtaact ccaaaaggag aaactgaact tactgctgag gaaagattac
     8101 ttcgtgcaat atttggagaa aaggctagag aagttagaga tacttcactt aaagtgcctc
     8161 atggtgaatc tggtataata gttgatgtaa aagtatttac tagagaaaat ggagatgatt
     8221 tatctccagg agtaaatgaa ttagtaagat gctatatagc taaaaagaga aaaataaaag
     8281 ttggagataa aatggctggt cgtcatggta ataaaggggt tatctcaaga gtattacctg
     8341 aagaagatat gccattcatg gaaaatggaa caccactaga cataatactt aacccacaag
     8401 gtataccatc acgtatgaac attggtcagg ttttagaagt tcatttagga cttgctgcta
     8461 agacattagg atggtatgta gcaacatcag tattcgatgg tgctaatgag tatgacataa
     8521 tggatgctct tgaagaagct gggtatccta gagatggtaa attaacttta tatgatggta
     8581 gaacaggtga gtcttttgac aacagaataa ctgttggata tatgtactac ttgaaactac
     8641 atcacttagt agatgaaaaa ctacatgcaa gaagtactgg accatactca ttagttactc
     8701 aacagccact aggtggtaaa gcacaatttg gtggacaaag atttggagag atggaggttt
     8761 gggctctgga agcatatgga gctgctcaca tacttcaaga aatacttact gttaagtctg
     8821 atgacgttgt aggtcgtgtt agaacatatg aagctatagt taaaggtgaa aatatacctg
     8881 aaccaggaat cccagaatca tttaaggttc ttataaaaga acttcaaagt ttatgcttag
     8941 atgtaaaagt attgacagat gaagaccaag aaatagaagt aagagaatct gtggatgaag
     9001 atgatacaat aggtgaattt gagctagatg ttgtaaatca tatgggagaa gttgaagaaa
     9061 gtaatataat agaagaaatt gaagatgatt ttgcagaaaa tgcagaagat gaggatatag
     9121 agaatttaga agaattcact gaagatgatt tatttgaaga agaaatagat tttgatagtg
     9181 atgactttga tatgtaaatt taattaatgt aaatctcaaa tagaagggag agaactcctt
     9241 gtttgaatta aacaatttcg agtcgataaa aatagcattg gcttctccag aaaaaataag
     9301 acaatggtct aggggagaag ttaaaaagcc agaaactata aattaccgta ctttaaaacc
     9361 agaaaaagat ggtcttttct gtgaaagaat atttggacca caaaaagact gggagtgcca
     9421 ctgtggtaaa tatagaagag ttagatataa aggtgtagtt tgtgatagat gtggagtaga
     9481 agtaactaaa tcaaaagtaa gaagagagag aatgggacat atagagctag ctgctcctat
     9541 gtctcacatc tggtacttca aaggtatacc aagtagaatg ggacttttac ttgatatgtc
     9601 accaagatcg ttagaaaaaa tattatactt tgcctcatat gtggtagttg atccaggaga
     9661 gactggatta aacgaaaaac aattgcttac agaaaaagaa tacagaactg ctcttgaaaa
     9721 gtatggatat acttttactg taggaatggg tgctgaagct gtaaagacat tactacaaaa
     9781 tatagattta gagcaacaaa gtaaagacct aagagcggag ttaaaagata gtacagggca
     9841 aaagaaagtt agaacaataa gaagattaga agttgtagag gcatttaaaa agtctggaaa
     9901 taaaccagaa tggatgattt tagatgcaat accagtaata ccaccagatt taagaccaat
     9961 ggtacaactt gatggtggaa gatttgcgac ttcagaccta aatgatttat atagaagagt
    10021 tataaataga aacaatagac ttaaaagatt attagagctt ggagctccag atataattgt
    10081 aagaaatgaa aaaagaatgc ttcaagaagc tgttgatgca ttgatagata atggtagaag
    10141 aggtagacct gtaacaggac ctggaaatag accacttaaa tctttatcag atatgttaaa
    10201 aggtaagcaa ggtcgtttcc gtcaaaactt acttggtaag cgtgttgact actcaggacg
    10261 ttctgttata gttgttggac cagaacttaa attttatcaa tgtggacttc caaagaagat
    10321 ggcattagaa ttattcaagc catttgttat ggataaatta gttaaagaag gttatgcaca
    10381 taatataaaa agtgcgaaat ctatagtaga aaaagttaag ccagaagttt gggatgtttt
    10441 agaagatgtt ataaaaagtc atccagttct tcttaaccgt gcaccgactc tacatagatt
    10501 aggtatacaa gcatttgaac caatcttagt tgaaggtaag gctataaaac tacatcctct
    10561 tgtatgtaca gcttataatg cagactttga tggtgaccaa atggcagttc atgtaccttt
    10621 atcagtagaa gcacaagcag aagcaagatt cttaatgctt tctgtaaata atatacttgc
    10681 tcctaaagat ggttcaccta taactactcc atctcaggat atggttttag gttgctatta
    10741 tctaacaata gaagcccaag atggagctaa aggaacaggt atggtattta aagactttaa
    10801 tgaactatta cttgcttatt acaataaatc agttcatcta catgcattag tgaaacttaa
    10861 ggtaacactt gaagatggaa gaagttcatt ggttgaaagt actgttggta gatttatatt
    10921 taatgaaaat atacctcaag acttaggttt tgtagataga aaagaaaatc catttgcact
    10981 tgaagttgat ttcttagcag ataaaaaatc tcttggtaaa ataatagata aatgctttag
    11041 aaaacacgga aatacagaaa cagctgaatt actagattat ataaaagctc taggatttaa
    11101 atattctaca ttaggtggca taacagttgc tgttgatgat atgagtgtcc cagaagaaaa
    11161 gaaagtattt atagctgagg cagaagctaa agttgataag tatgaaaaag catacagaag
    11221 aggtctaatc tctgatgaag aaagatatga aaaagttata gagacatgga cagaaacaac
    11281 tgataaagtt actgatgctc ttatgggtgg actagataga ttaaataata tatatataat
    11341 ggcacattca ggagccagag gttctaaaaa ccaaattaga cagctggcag gtatgcgtgg
    11401 tcttatggca aatgcatctg gtaaaacagt tgagatacca gttaaatcta atttccgtga
    11461 aggtttatca gtactagaat actttacatc ttcacatggt gccagaaaag gtcttgccga
    11521 tacagctata cgtacagctg aatctggata tttaacaaga agacttgttg atgtaagtca
    11581 agatgttatt gtaagggaaa tagattgtgg aacagaagat actacagaga tttatgctat
    11641 aaaagaagga aatgaagtta tagaagagat atatgataga attgtaggaa gatatactat
    11701 agaccctata ttaaatcctg aaactggaga agttatagtt gaggctgatt caatgataca
    11761 agaagatgaa gcagaaacta tagtagcttt aggaattgaa aaaattagga taagaacagt
    11821 tcttaactgt aaaactaatc atggagtttg ttctaagtgt tatggtagaa acttggcaac
    11881 aggaaaagaa gttaatatag gtgaagcagt tggtataata gcagctcaat ctatcggtga
    11941 gccgggtact cagcttacaa tgcgtacatt ccatactgga ggagttgcag gagctgatat
    12001 aactcaaggt ctaccaaggg ttgaagaatt atttgaagct agaaaaccaa aaggattagc
    12061 tgtaataact gaagtatctg gtagagttga aattgatgaa acaggaaaga gaaaagaagt
    12121 aaatgtaata ccagaagaag gcgagactca aacatatgta attccatatg gttctagatt
    12181 aaaagttaag caaggtcaaa tgctagaggc tggagaccct ctaacacaag gatttataaa
    12241 tcctcatgat atagtaagag taaatggtgt taagggagtt caagaatata tagttaaaga
    12301 agttcaaaga gtgtatagac ttcaaggggt tgatgttaat gataagcata tagaagttat
    12361 agtaagacaa atgctatcta aagtaaaagt tgaagaccca ggagatacag atttattgcc
    12421 aggtggatat gaagatgtat taacattcaa tgaatgtaat aaagatgcta tagataaagg
    12481 tctaagacca gcagttgcta aaagagtttt acttggtata actaaagcat ctcttgcaac
    12541 tgattcattc ttatcagcag cttctttcca agaaacaaca agagtattaa cagaggcagc
    12601 aataaaaggt aaagaagacc acttaatagg acttaaagaa aatgttatat taggtaagtt
    12661 aataccagca ggaacaggaa tgaagaaata tagaaatata gctgttgaaa aaattgaaga
    12721 ttaatagcat atagagtaaa gaaatcttga caaccattat ttgtggtgtt aaaatagtaa
    12781 agtgtgttgt ttaaaagtac actaagggct tgaacaagtt cttagtgact tttagatggc
    12841 aataaatgag aactaaaaag catcaagcta gaaaagtgct aatatcacat atttatgtgt
    12901 tatagacatt aaattgtaag taacgaatgt tacaatcagt cagtatgaat attcatattg
    12961 atgtagttgg cggtcactga taagatcgaa aatttggaag gaggtgcaga tgatgccaac
    13021 aattaaccaa ttagttcgta aaagtagaaa agcgctagag aagaaatcta ctgctccagc
    13081 attacaaaaa ggttacaact ctttaaataa gaaagtaact gacgctagtg ccccacaaaa
    13141 aagaggggtt tgtacttcag taaaaacagt tactcctaag aagcctaact cagctttaag
    13201 aaaagttgcc agagttagat taactaatgg tatagaagtt tctgcttata taccaggaga
    13261 aggacacaac ttacaagagc atagtgttgt tcttataaga ggaggaagag taaaagacct
    13321 tccaggggtt agataccata tactaagagg tactctagat acagcaggtg ttgataagag
    13381 aagacaatca agatctaaat acggtgcgaa gagacctaaa gaagctaaaa agtaaaaaca
    13441 attaatgatt gattatagtt cggtgcttta aatatatata tatttacggc atcacggcat
    13501 taaatgattt atgtcgagta cctatgattt aagttaaata attaaggagg gaagcgaaat
    13561 gccaagaaaa ggtaatattc caaaaagaga agttttacca gatcctatgt atgggagtaa
    13621 ggtagttact aaattaataa ataatctaat ggtagacgga aaaaaaggaa agtctcaaag
    13681 aatagtttat gatgctttcg caattgttgc tgaaaagaca ggagaagaag ctttagaagt
    13741 atttaataaa gcaatggata atataatgcc tgttttagaa gtaaaagcaa gaagagttgg
    13801 tggggcaaac taccaagtgc caatcgaagt tagacctgaa agaagacaaa cattaggttt
    13861 aagatggcta gtaaaatata ctagagctcg tggagaaaaa ggaatggttg aaaagctagc
    13921 taaagagata atggacgcag ctaacaacac tggagcttca gttaagaaaa aagaagatac
    13981 tcataaaatg gcagaagcta ataaagcatt tgctcattac agatggtagg atatatagat
    14041 atcttataaa attgaggata tcataaggag gataaccatg gctagaaagt ttcctttgga
    14101 aagaactagg aatataggaa tcatggctca tatagatgca ggaaaaacta ctactacaga
    14161 aagaatcctg ttttatactg ggcaaactca taaaatagga gaaactcatg aaggagcttc
    14221 tcaaatggac tggatggagc aagaaaagga aagaggtata acaataactt ctgccgctac
    14281 tactgcttca tggaaagacc atagaataaa cataatagat actcctggac acgtggactt
    14341 cacagttgag gttgaaagat ctctaagagt tcttgacggt tcagttgctg tattctgtgc
    14401 aaaaggtggg gttgagcctc aatcagaaaa tgtatggaga caagctgaaa cttatggagt
    14461 acctagaata gcttttgtaa ataaaatgga tatattaggt gcagatttct acaatgttgt
    14521 aagcatgatg aaatctagat taaattctaa tgcagttcct atgcaattac caataggtaa
    14581 agaagattca tttataggta taatagactt attaaaaatg gatgctgtta tatacaaaga
    14641 cgacctaggg gttgaaatgg aagaaacaga tataccagaa gatatgaaag aattagctgc
    14701 tgagtggaga gaaaaattag ttgaatcagt agctgaaact gatgaagaat taatgatgaa
    14761 ataccttgaa ggtgaagaac ttactataga tgaattaaaa gttgctataa gaaaagctac
    14821 tatagcttgt gaaatgaacc cagttttctg tggtacagct tatagaaaca aaggtgttca
    14881 gttagtaata gatgcagttt tagattactt accagcgcca actgatatac cagctataaa
    14941 aggtatatta gcagatggag aagaagctga aagacattct tctgatgaag agccattctc
    15001 tgcattagca ttcaaaataa tgactgaccc attcgttgga aaactagcgt tcttcagagt
    15061 ttattctgga acattagaat caggttctta tgttttaaat gcaactaaga ataagagaga
    15121 aagaattggt cgtatattac aaatgcatgc taatacaaga gaagaaataa ctaaagtgta
    15181 tgctggagat atagcagcag cagtaggatt aaaagatact actactggag acacattatg
    15241 tgaccctgct aatccaataa tacttgaatc tatggaattc cctgagccag ttatatctgt
    15301 tgctatagaa ccaagttcta aagcagctca agaaaaaatg ggtatagctc ttcaaaaatt
    15361 agctgaagaa gacccaactt tcacagttaa gactgaccaa gaaacaggac aaactataat
    15421 atctggtatg ggtgaattac acttagagat aatagtagat agattattaa gagaatttaa
    15481 agtagaagct aaagttggtg caccacaagt tgcatataga gagactataa ctcaaccagt
    15541 tgatgttgaa tacaagtact ctaagcaatc aggtggtaga ggacaatacg gtcacgttaa
    15601 gattagagtt gctcctcaag agccaggtga aggatacaaa ttcacaaaca aaactgttgg
    15661 tggatcagta ccaaaagaat atgttggtcc agttgacatg ggtatacaag gagctatgca
    15721 atctggtata gttgctggat atccagttgt agacgttgct gttgagttat atgatggttc
    15781 ttaccatgag gttgactctt ctgagatggc gtttaagatg gctggttcaa tggcattcaa
    15841 agatgctatg aagaaaggta atgcagttct tttagagcct tacttcaaag tagaagttgt
    15901 tactccagaa gattacatgg gagatgttat gggtgactta aactcaagaa gaggattaat
    15961 ccaaggtatg gaagctagaa gtggtgcaca agttataaat gcattcgttc cactttcaga
    16021 aatgtttgga tactcaacag acctaagatc ttcaactcaa ggtcgtgcaa cttacacaat
    16081 gatattcgat cactatgagc aagttccagc ttcagttgct aagaaaatag ctgaaggaaa
    16141 ataatttaaa aataattaat aatataaata taaaaaataa tcagctagat gagagatatc
    16201 tctcatctag cacaagat
//
LOCUS       DAFAZV010000072        15201 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFAZV010000072 DAFAZV010000000
VERSION     DAFAZV010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15201
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.072"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(511..1149)
                     /locus_tag="KOU88_003592"
     CDS             complement(511..1149)
                     /locus_tag="KOU88_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HBK3213421.1"
                     /translation="MLIHLVKKDILIVKKYVLLILFIAIGIPLFILWRLPPFAQILGF
                     VLSIIFSEFMLCQYLLLKESQYSKASVLLCSTPYPRRGLVQSKYVLFAMVFIYCTLVY
                     WIENLLIPQIGTFDLTYILIVLLISSIIYGVYMPIQYKLGYETTKFFFVVIIMASSFV
                     LPLTIAHSNFEIPFIYQYPSMIVNIVLFLLSLIILLASMFISIKIFSNKELV"
     gene            complement(1152..2009)
                     /locus_tag="KOU88_003593"
     CDS             complement(1152..2009)
                     /locus_tag="KOU88_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213422.1"
                     /translation="MENILEVYNLNKTYTDFSLSNISFALPEDCITGFIGVNGAGKTT
                     TIRSILDVVKRDSGKIKIFGKDFDGNEKELKNRIGVVFDDSYFYEELSMAEMKSIIAP
                     SYDNWCEEDYQQNMKRFNLNPKQKIDTLSKGMKMKFALALALSHKAEFLIMDEPTSGL
                     DPLIRSQILDILTGYMKKCGRGVFFSTHITSDLDKIADMIVMIDNGRIILEREKDTLL
                     DEHRKVKGDIQFLNDETKKLFLNLEITGYGFIGITSKINEVQKNMPDILIERPTIEDI
                     MLAYIERRE"
     gene            complement(2011..2385)
                     /locus_tag="KOU88_003594"
     CDS             complement(2011..2385)
                     /locus_tag="KOU88_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3213423.1"
                     /translation="MKVLISNTSDKPLYQQIKEQIKEAIFTEELKEGDAMPSIRNFAN
                     DLKVSILTIRRVYEELENEGFLTRQVGIGTFISTGNLEILRDSKRRIVEQKMADMIKD
                     AKALGITQIELQEMMDILYQED"
     gene            complement(3564..4754)
                     /locus_tag="KOU88_003595"
     CDS             complement(3564..4754)
                     /locus_tag="KOU88_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBK3213424.1"
                     /translation="MSDMLLWFSVVLVLFAIGDLIASKTKAKVSAVFVTLLLFLILFV
                     TKAIPADIIEKAGMTAAASWSVPMIMFSMGTMLNVKQFIDEWRTVLTAWLGIVAVIVC
                     VSLCIPLFGKSTVLTSIPVINGALPATTIMTQAALEKGLTLAAATATVVFAIQKFIGT
                     PIASRAALQEANRLLVEYHEAKSKGIDLANVDTDKKEAENTGTKVKQAFCEKYDKYYS
                     TNVCIFFIALFSYLGYELSEIIHVNYSIVCLVVGVIVTRIGIVPKDILEKGKIKGFIN
                     MVVFAAVIPSLAKVSLTDLISLFVPIVGMFAASIIGIFLMMKVLPGWKIIGSKPLAFG
                     VGFCQMLGFPTTYLISNEVCNAVGETEEERAYLMSKIMPKLVVGGMACMISIVVAGLM
                     VPML"
     gene            complement(4770..6725)
                     /locus_tag="KOU88_003596"
     CDS             complement(4770..6725)
                     /locus_tag="KOU88_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBK3213425.1"
                     /translation="MEKIKIESSDIFEYIFPHDISCSPDGKHIAYIISNINEEKDCYE
                     HDLYVMDIKTEKQIHMTQTKDVTSFSWISNTELLFTSKRNKPKASTTDFYTISIEGGE
                     AKKAFSIPKACSVPVSLGNKLWLLTTKNPTDSKKSEPDRAVEGVDYWTFTDKPFIRDG
                     ENFSQRRRVTLELYQEGENITKAITPKFCEVAGVDVSSDKNRILYTGQIYEDCATPFS
                     GLWEYHIDSGETKELVPQGKYQISLAKYIGKDKVMLQASTLDRSITQNHDIFILDLST
                     SEINMIASPDGMYATLLDVDAVYGGGRSNKVIGDKFIGARICRTMTEFNEFDTKTGNI
                     RIITKVDAFTSFDIYDNTMYTVMLKDYELAEIYSIDMTTGTMKKMTAFSEPYLDTHKV
                     SLPEKLTFVAKNKEEVDGFVIPPIDAKEGEKYPAVLFIHGGPKWAYGYMFTHLKQCVT
                     SKGMYVIYCNPHGGDGYGEKFLEMVERWGYVDYEHLMEFVDTCIEKYPGIDADRLGVA
                     GGSYGGYMTNWIIGHTDRFKAAVSQRGISNLITASLIIDFGDRIMKQTCGDKTPWNHE
                     EVLWNHSPIKYVKNVKTPTLFLHSDRDYRCFMGDTFQMFTALKQLGVDTEMYLFHGDT
                     HGLSRNGRPSNRIARANAIVDWFERYL"
     gene            complement(6742..8808)
                     /locus_tag="KOU88_003597"
     CDS             complement(6742..8808)
                     /locus_tag="KOU88_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HBK3213426.1"
                     /translation="MKEVVGSLKKITKERIENTMKKLFTSETFLEYQFISDCQISPNG
                     GYTAFIVKKADIKENGYTSQVYILNNKTGELKQITSINSVGAYAWEDENTILFPALRN
                     EKVKDAVKNGKQCMSYYALSLNGGEAEELFRLPIKGGKLNPIGKGLYAVVDSYDNDRP
                     IVEGLPEEEQQKKINAYNKRHYEHFKEIPYAVNGEGYISRKRKRLYVYDSNINELKAI
                     TAPMFNVVGMKISDGKILYIGQEFKDVKGLKNGVYVFDTNTNTNVCILEKDKYIIKGF
                     ELYQNQVILNLTDALSYGNGENGDFYTIDIDTKEMKLLSGHQHHCIGNTVTSDVKMGA
                     GQTTKVDGEYIYYTSTVDMDCIIERIHIPTGKQEKVTQTGSVDFIDVKDGNIVCVGCL
                     GNGLPEVYTVENGTLCKKTHLNDHILEEYKISVPEYIESKGSSKWEIQGYVYKPVDYE
                     VGKKYPAVLAIHGGPRLTYGPYFMNEIQVFTSAGYFVFFCNPRGSEGRGNAFADIRKQ
                     FGDIDYIDFMEFTDTVLEKYTDIDKTKLAVEGGSYGGFMTNWIIGHTNRFAVACAQRS
                     IANWSGMEGTTDIGYYFCKGQTGASHMENHELQWKQSPLAYADKCVTPTLFLHGEKDY
                     RCYMQEAFQMFSALKIHGCPTKLCLFEGENHELSRSGRPKQKLQRLVEMLDWFSVYIK
                     KDNIGQ"
     gene            complement(9124..9774)
                     /locus_tag="KOU88_003598"
     CDS             complement(9124..9774)
                     /locus_tag="KOU88_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009905011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3213427.1"
                     /translation="MKVKSNLDEILYHKIIESLIRGEYSVGQKILLNDLCEKFEVSRT
                     PVVQAVKMLNKDGVLTIMTNGKVYVPEYEYDMVKQVCETRTLIETYALEKMMQEEEEV
                     FQQKLDVIKRYSDKCEEYYRQEKSVELALADLELHKAIVEGANNEILNDVYVGIQGRF
                     IVVNYLIRPLKNRNYEGTVQDHFEILKFIEDRDTKKAVDKLRNHIQGTIKRFCEDE"
     gene            complement(10718..11053)
                     /locus_tag="KOU88_003599"
                     /pseudo
     CDS             complement(10718..11053)
                     /locus_tag="KOU88_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427885.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
     gene            complement(11151..11831)
                     /locus_tag="KOU88_003600"
     CDS             complement(11151..11831)
                     /locus_tag="KOU88_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003440161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213428.1"
                     /translation="MIHLMKLELKKVGLKRYFLFSMLGIFLCMFFVFTGLNDKSTSIY
                     DYDVTFRTISLFFCFYYIILFAVLNVAYIINEYTNKTILILFSYPLDRKKLILSKLLL
                     ITTLMISSMIVGYICCFTFVVVLDKYFNLVIGDFHISILSYWIPGAIKSIIVFCSLGI
                     WTLVVGMIRKSIPVTLVSSIIFINLRQFILAGTNTTQDSLISVFIIVGITVIGIYYIL
                     NHKVTEID"
     gene            complement(11828..12754)
                     /locus_tag="KOU88_003601"
     CDS             complement(11828..12754)
                     /locus_tag="KOU88_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213429.1"
                     /translation="MNYIIETHQLKKIYKDKAVVNAVNIHVKKGEIYGFVGPNGAGKS
                     TVMKMLLNLVNPNSGEIVMFGKKVAETDFEILKKIGTIIENPYLYENLTAKQNLDLHC
                     EYMGYYNKEHISEVLECVGLSKQSNKKVSKYSLGMKQRLAIARAILTKPELLILDEPI
                     NALDPEGIREMRELFRKLNTDYGITIFISSHILSEVEQIADTIGIIQDGKLIKEISMS
                     DIHKYQTDYVEVDVDNVELAGYLLEKEFGIKDFKITSESCIEIYDLRKDVKEISKIFI
                     QNQIGINSIGRKQSSLEDYFFQTTGTGGKETL"
     gene            complement(12827..13744)
                     /locus_tag="KOU88_003602"
     CDS             complement(12827..13744)
                     /locus_tag="KOU88_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK3213430.1"
                     /translation="MELFLVVISIVLFALYLKERNKSKKMESDYKYINSRLRDITNDD
                     EINYILVPSDISIVKETAVDINKLVEKFYSRQINYNRSEKAILQIFTNISHDLRTPIT
                     VLKGYIEMLYLQSQKEELSSSMRATVEKMQTNSNELVNSINNLFNMAKIQSGDMILNL
                     QKSNLTQLCHEIILEFYDLLDKENFNVEVNIEDRPIYANVDTEALQRILKNLIDNAIK
                     YGSDGRFLGISLYEKEKHVFIDIEDKGSGISETEKEHIFTRAYTADRKKGNGLGLAIS
                     QGLVNSMGGSIYVNSRPNVKTVFTVKLKS"
     gene            complement(13744..14433)
                     /locus_tag="KOU88_003603"
     CDS             complement(13744..14433)
                     /locus_tag="KOU88_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213431.1"
                     /translation="MDILLVEDDKNIREMVYDFLISENYSVKTAIDGNTAIEIFKNYS
                     FDIILLDLMLPKSSGFEVLKYIRSVSVVPVIITTAKDSDTDKMLGLNLGADDYITKPF
                     SIVELLARIKANIRRATVYSSSRNSQDMVIRYKDLIINISKYVVSKNGIDLNLTHTEF
                     EIVKLLATNQGRAFSKEQLYNAIWKEPYYGNENVLNTHINRLRNKLSDGIEKNNYIKT
                     LWGIGYKMEEE"
     gene            complement(14841..15146)
                     /locus_tag="KOU88_003604"
     CDS             complement(14841..15146)
                     /locus_tag="KOU88_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213432.1"
                     /translation="MPSMIMEVVGVLFIAIGLILTFIEIKGNFPSFYGFGQNSIGKNA
                     VGIIAAGIALIFFRNGIDSIDSIATYGVFLAIELVVIVAYFLIRKKFTKEDKHLRTN"
BASE COUNT         5196 a         2621 c         1703 g         5681 t
ORIGIN      
        1 atattaaacc aattatattt tcgtcatttc agcaatgaaa aagaagctta tctctatttt
       61 gagacagctt ctttttatta acttcctact ttttattagt tttctaaaat tgaaaagctt
      121 tatttatagg attccttaga tttatatttt gacgatataa ttttttaaaa acatcttaaa
      181 aaatggtata caatacacac aatcatactc ataattgaaa aataatcaat ggaaaataaa
      241 attactggat attatctatt aaaaaataca aattgattca caagaaacat ataatctata
      301 atattatgat gttactctgc cacaccaagt aactttattt tcaagtaacc ttttcatacc
      361 atctaacttt actcaataaa aatggcaata taaatatgta ctctattttt tacttttaaa
      421 tatctgacaa gctttatata ctattggaag taagatacaa agtaaaacag cccaatctgg
      481 caaatgtggc atataaaagt cccccttacc ttatacaagc tccttattac taaaaatttt
      541 aatagaaata aacattgaag ctaacagtat aattaaactt aaaaggaaca atacaatatt
      601 cactatcatg gatggatact gatatataaa tggaatttca aaattgctgt gagctatagt
      661 taatggtaat acaaatgatg aagccatgat tatcaccacg aaaaagaatt ttgttgtttc
      721 atatcctaat ttatattgaa taggcatata aactccataa ataatagaac ttattaataa
      781 aacaatcaaa atatatgtca agtcaaaagt tcctatttgt ggaataagta aattttcaat
      841 ccagtaaact aatgtacaat agataaatac cattgcaaat aaaacatact tagattgaac
      901 taagccacgt ctaggataag gagttgaaca aagtaataca gatgcttttg aatattgact
      961 ctcctttaat aatagatact gacacagcat aaattctgaa aatataattg atagtacaaa
     1021 tcccaatatt tgtgcaaatg gaggtaaacg ccataatata aataatggga ttcctattgc
     1081 aataaataat atcaacaata catatttttt tacaatcaga atatcttttt taactaaatg
     1141 aatcaacata attactctct cctttcaata tatgcaagca taatatcttc aattgtagga
     1201 cgctctatta aaatatctgg catatttttt tgcacttcat taatttttga ggtaatccct
     1261 ataaaaccat aacctgtaat ttctaaattt aaaaataatt ttttggtttc atcatttaga
     1321 aattgaatat ccccttttac ttttctatgt tcgtccaata gagtatcttt ttcacgctct
     1381 aatataatac gtccattgtc aatcataaca atcatatctg ctattttgtc taaatcagat
     1441 gttatatgag tggaaaagaa aacaccacga ccacatttct tcatatatcc tgttagtatg
     1501 tcaagtatct gactacggat tagtgggtct aaaccacttg taggctcatc cataattaaa
     1561 aactcagctt tatgcgataa tgctaatgct aaagcaaatt tcattttcat tccttttgaa
     1621 agtgtatcaa tcttttgttt tgggttaaga ttaaaacgct tcatattttg ttgataatct
     1681 tcttcacacc aattatcata tgaaggtgca ataatacttt tcatttctgc cattgacaac
     1741 tcctcataga aatatgaatc atcaaataca actccaattc gattttttaa ttccttctca
     1801 tttccatcga aatctttacc aaagattttt atttttccac tatcacgctt tacgacatcc
     1861 aatatcgaac ggattgttgt tgtttttcct gctccattaa cacctataaa tccagttata
     1921 caatcttctg gtaatgcaaa gcttatatta gataatgaaa aatcggtata agtcttattt
     1981 aagttataaa cttctaaaat attttccata ttaatcctcc tgatatagaa tatccatcat
     2041 ttcttgtaac tctatctgtg taattcctag tgcttttgca tccttaatca tatctgccat
     2101 tttttgttca actatacgtc tctttgagtc tcttagtatt tctaaatttc cagttgaaat
     2161 aaatgttcct attccaactt ggcgtgtaag aaagccttca ttttcaagtt cttcatacac
     2221 tcgtctaata gtcaaaatac taacttttaa atcattagca aaatttctta tggatggcat
     2281 tgcatcccct tctttcagtt cttcagtaaa tattgcttct ttaatttgct ctttaatttg
     2341 ttggtataat ggcttatctg atgtgttaga aatgagcact ttcatttttt atcaccccct
     2401 ttttatcatt ttcagtgtga tgttgttata tacacactat acacttagag cacttttttg
     2461 tcaatataaa agatgtaaaa tattactatg acaaaataaa tatgaatgaa atattagaga
     2521 tttttgatag ctataaacac tttttaaaac cacataagat aggatgtatt aaatatttat
     2581 taaaagtaag aattgaatat ctaaaaaaaa gaggaatcct gtatgaatga tttgtttgat
     2641 gataaattaa gttataaact atttataaaa aacataaagg aataaatcca tttctaatta
     2701 caaacatact aaaaaattta gatagtaata aatagatagt aataaatggg atgaatttat
     2761 aagaatttgg atagaggaaa gagttattca agagtgtaga ctagaggtaa actctatatt
     2821 aaaaaaattt aaatttggat attatgatgc atggaatatt tgcagaagta accttgctat
     2881 aagtatagaa gatttttttg attaaaaaag ataatactct aaaatgtgag aatttcaaca
     2941 ttcaatactg tgctttaaat aatatcactg caaaatacca tccacctttt accataattg
     3001 aataccctaa ttattttaaa aaagaaaaca ttagaaacgg aaaaccttgt atatataaaa
     3061 taaaaaatac taacttctaa aacacgaata ctctttgata aataaaacaa aaaataattt
     3121 taataattaa aattggctat ctcaaactag agataagtct ctttctcact tttaaaactt
     3181 tgaaaatata ttcgatttcg tacaaaaaag agtgccttag aactaaaaag ttcactttgt
     3241 ggcactccct tttttctcct ctttttaatt ctttctaaag attttccaaa aatattatta
     3301 aataccctat ttatagataa atcaagttaa agttttgttt tagaaaataa aaataaactg
     3361 taactattag aatagcaaat aaaaaatctg tttcttgata aaatcaagat tataatgcta
     3421 aaaagaaaat attcttataa taaattaact aatataaaat tcgtttataa attaatactg
     3481 actttctagc tttatttata aattaatact actttttagc ttctcctata aattaacacc
     3541 acttttttaa ctatgaaacc tatctacaac attggtacca taagaccagc taccacaata
     3601 gaaatcatac aagccatacc accaactacc agcttaggca taatcttaga catcaaatat
     3661 gctctttctt cttccgtttc tccaacagca ttacacactt catttgaaat taaatatgta
     3721 gttgggaatc ccaacatctg acaaaaccct actccaaaag caagaggttt agaaccgata
     3781 attttccaac ctggtaacac cttcatcata aggaatatac caatgataga agctgcaaac
     3841 atacctacaa ttggtacaaa aagactaatt aaatctgtca aagaaacttt tgctaaagaa
     3901 ggaataacag ctgcaaacac aaccatgttg ataaatccct tgatttttcc tttttccaaa
     3961 atgtcttttg gtacaatacc aatacgtgtt acaataacac caacaacaag acatacaata
     4021 gaataattta catgaataat ctctgaaagt tcatacccta gataagagaa taatgctata
     4081 aaaaatatac aaacatttgt agaataatat ttatcgtatt tttcacagaa agcttgtttt
     4141 acttttgtgc ctgtattctc tgcttctttc ttatcagtat caacatttgc taaatcaatg
     4201 ccttttgatt ttgcttcatg atattctact aaaagacggt ttgcctcttg taacgctgct
     4261 cttgaagcta ttggtgtacc aataaacttc tgaattgcaa atacaactgt tgctgtagct
     4321 gctgcaagtg tcagtccttt ttctagtgct gcttgtgtca taatagtagt agcaggtaaa
     4381 gctccattta taactggtat gcttgtcaat actgttgatt ttccaaacaa aggaatacat
     4441 aatgagacac agactataac tgctacaatt ccaagccatg ctgtcaatac tgttctccat
     4501 tcgtctataa attgtttaac attcaacatt gttcccatac taaacataat cattggaaca
     4561 ctccaactag ctgctgcggt catacctgct ttttcaataa tatcagctgg tattgctttt
     4621 gtgacaaata gaatcaaaaa taaaagtagt gtaacaaata cagctgatac ttttgctttt
     4681 gttttgcttg caattaaatc cccaatagca aataaaacta atacgacact aaaccataat
     4741 aacatatcac tcatagaata acccccttat tataaatatc tttcaaacca atctacaata
     4801 gcatttgctc ttgcaattct attagatggt cttccatttc tagacaatcc atgtgtatct
     4861 ccgtggaaca aatacatttc tgtatctaca ccaagctgtt ttaatgctgt aaacatttgg
     4921 aaagtatccc ccataaaaca tctataatcc ctatcactat gtaagaacaa tgttggtgtc
     4981 ttaacatttt tcacatattt aataggtgaa tgattccaaa gaacctcctc atgattccaa
     5041 ggcgtcttat ctccacaagt ctgcttcata attctatccc caaagtcaat aattaaagaa
     5101 gctgtaatca agttactaat acctctttga gaaactgctg ctttgaaacg gtctgtatga
     5161 ccaattatcc agtttgtcat ataaccaccg taacttcccc ctgcaacccc taagcggtct
     5221 gcatcaatcc caggatattt ttcaatacaa gtatctacaa attccataag atgctcatag
     5281 tcaacatacc cccatctttc taccatttct aagaattttt caccataacc gtcaccacca
     5341 tgagggttac aataaatcac atacattccc tttgatgtta cacactgctt caagtgtgta
     5401 aacatatagc catatgccca tttaggtcca ccatgaatga acaatacagc aggatatttt
     5461 tcgccttctt tagcatctat aggcggtata acaaaaccat caacttcttc tttatttttt
     5521 gctacaaacg tcaatttttc aggtaatgaa accttatgag tatctaaata tggttcagaa
     5581 aaagcagtca tttttttcat tgtacctgta gtcatatcaa tgctatatat ttctgctaac
     5641 tcataatctt tcaacattac tgtgtacatg gtgttgtcgt aaatatcaaa agatgtaaaa
     5701 gcatctactt ttgtgatgat acgtatatta cctgtctttg tatcaaactc attaaattct
     5761 gtcatagttc tgcaaattct tgcaccaata aatttgtctc ctataacttt attactacgt
     5821 ccaccaccat atactgcatc tacatccagt aatgtagcat acataccatc tggactagca
     5881 atcatattta tttcactagt actcaaatca agtataaaaa tatcatgatt ctgtgtaata
     5941 gaacggtcta atgttgaagc ttgcaacatt actttatctt tgccaatata ttttgccaaa
     6001 cttatttggt actttccttg tggtacaagt tctttggttt caccactgtc tatatgatac
     6061 tcccaaagtc cagaaaaagg agttgcacaa tcttcataaa tctgaccagt atataaaatt
     6121 ctgtttttat cagaagaaac gtctacacct gctacttcac aaaattttgg tgtaatggct
     6181 tttgttatat tttcaccttc ttgatataat tctaatgtta cacgtcttct ttgagaaaaa
     6241 ttttctccat ctcttataaa aggtttatct gtaaatgtcc aataatctac accctctact
     6301 gccctatctg gttctgattt tttagaatcc gttggatttt ttgttgtcag taaccacaat
     6361 ttatttccaa gtgatacagg tacgctacaa gcttttggaa tagaaaatgc tttttttgct
     6421 tctcctcctt ctatagaaat agtgtaaaaa tctgttgtac ttgcttttgg cttatttctt
     6481 ttagatgtaa aaagtagttc tgtattagaa atccaactaa atgatgttac atcttttgtt
     6541 tgagtcatat gtatttgttt ttctgttttg atgtccatca catataagtc atgttcatag
     6601 cagtcttttt cctcgttgat atttgatata atataagcaa tatgctttcc atcaggtgaa
     6661 caagaaatat catgagggaa tatatattca aaaatatctg aactttcaat ctttattttt
     6721 tccattttta tattctcctt tctactgtcc tatgttatct ttttttatat ataccgaaaa
     6781 ccaatctagc atttcaacta atctttgtag cttttgtttt ggtctaccag aacgagacag
     6841 ttcatggttt tctccttcaa atagacaaag ttttgtagga cacccatgaa ttttcaatgc
     6901 tgaaaacatc tggaatgctt cttgcatata gcatctatag tctttttcac catgtaaaaa
     6961 taaagtcggt gtaacacatt tatcagcata agcaagaggt gactgtttcc attgaagctc
     7021 gtggttttcc atatgagaag cacctgtttg tcctttgcag aaataataac caatatctgt
     7081 tgtaccctcc atgccactcc agtttgcaat agaacgctga gcacaagcaa cagcaaaacg
     7141 gtttgtatga ccaattatcc aattcgtcat aaatccacca taacttccac cttcaacagc
     7201 caattttgtt ttatcaatgt ctgtatattt ttcaagtaca gtatctgtaa attccataaa
     7261 atctatataa tcaatatctc caaactgttt cctaatatct gcaaaagcat tgccacgacc
     7321 ttcagacccc cttgggttac agaagaatac aaagtaacct gcacttgtaa atacctgtat
     7381 ctcattcata aaatatggtc catatgtcaa tcttggtcct ccatgaatcg ccaatacagc
     7441 tggatatttt ttccccacct cataatctac tggtttatat acgtatcctt gtatttccca
     7501 tttagaactt ccttttgact ctatgtattc tggcacagaa attttatatt cctctaaaat
     7561 atggtcattt aaatgtgttt tcttacacaa tgttccattc tctactgtat aaacttctgg
     7621 taatccattt cctaaacaac ccacacatac aatattgcca tcttttacat ctataaaatc
     7681 aactgaacct gtctgtgtta ctttttcctg ttttcctgtt ggaatatgta ttctttcaat
     7741 aatgcagtcc atatctactg tagaagtgta ataaatatat tctccatcta cctttgttgt
     7801 ctgaccagca cccattttaa catcagatgt tactgtattt ccaatacaat gatgttgatg
     7861 ccctgaaaga agtttcattt ctttcgtatc aatatcaata gtataaaaat ctccattttc
     7921 tccatttcca taagataaag catcagttag gtttagtatc acttgatttt gatataattc
     7981 aaaacctttt ataatatact tatctttttc taatatacag acatttgtgt ttgtgtttgt
     8041 atcaaataca tagaccccat ttttcaaacc ttttacatct ttaaactctt gccctatata
     8101 taagattttt ccatcactta ttttcatacc tacaacatta aacataggtg ctgtaattgc
     8161 cttcaactca tttatattac tgtcgtatac atataggcgt tttctttttc tgctaatata
     8221 tccctcccca ttgacagcat aaggaatttc tttgaaatgt tcataatgtc ttttgttata
     8281 agcatttatt tttttctgtt gttcttcttc tggcaatccc tctacaatag gtcggtcatt
     8341 gtcataagaa tcaacaactg catacaaacc ttttcctata ggattcaatt taccaccttt
     8401 gatagggagt ctaaaaagtt cttctgcttc tccaccattt aaagataaag catagtaact
     8461 catgcattgc ttaccgtttt tgacagcatc ttttactttt tcatttcgca aagcagggaa
     8521 caagatagta ttttcatctt cccaggcata tgctccaaca gagtttatag acgttatttg
     8581 ttttaattcg ccagttttat tgtttaatat ataaacttgg cttgtgtaac cattctcttt
     8641 gatatcagct ttttttacaa taaatgctgt atatcctcca tttggtgata tttggcaatc
     8701 acttataaat tgatattcca aaaatgtttc actcgtaaat agctttttca tagtattttc
     8761 tatcctttct ttagtaattt ttttcaaact ccctaccacc tctttcattt tttattttaa
     8821 atttaaaata aaaaatttta aatttaaaat aaaaaatttt ataaaggtta tttttttagg
     8881 aagccttctg gcttccttgt aatatttgta atttaaagta tatttaatcc atgcttaatt
     8941 catacttaat ctatacttag tccatactta atctatattt aattcatact tagacttatt
     9001 tacactatat ttagattata tttattagat tatatttaga ttatgtttaa actataatta
     9061 gattatactt agactacatt tagcaactta atagataagt atatatagta acttcaaaac
     9121 ttattattca tcttcacaga atcttttaat agttccttga atatgatttc ttagtttatc
     9181 tactgctttt tttgtatctc tgtcttcaat gaattttaat atttcaaaat ggtcttgtac
     9241 tgttccttca taattacgat tttttaatgg tcgaattaaa tagttcacta ctataaatct
     9301 tccttgtata ccaacatata catcatttaa aatctcatta tttgcccctt ctacaatggc
     9361 tttatgtaat tccaaatctg ctagtgcaag ttctacagat ttttcttgac gatagtactc
     9421 ctcgcattta tcagagtatc tttttattac atctagcttt tgttgaaaaa cctcttcctc
     9481 ttcttgcatc attttttcta aagcatatgt ttcaatcagt gttctcgttt cacaaacttg
     9541 ttttaccata tcatattcat actctggtac gtacacttta ccatttgtca taatagtaag
     9601 cactccatct ttatttagca tttttactgc ttgtacaact ggtgttctgc ttacttcaaa
     9661 tttttcacaa aggtcattta gtaatatttt ttgacctaca gagtattcac cacgaataag
     9721 actttcaata atcttatgat ataaaatttc atctaaattt gactttactt tcactactct
     9781 caccttattt ctattctttt gccatattat attgaattac tggactttaa ttacttttag
     9841 taatattttt aaagtagaaa ttcttatttg atagtacttt tgtactacaa tttaaattat
     9901 tgtactgtaa atcatgctct tatactatag attaattcat tgtattgcaa atcaagttat
     9961 tgtactatag attaaatcgt tgtacttcaa atcaagttat tgtactatag attaaatcgt
    10021 tgtactttaa attaaactat tatactatag attaattcat tgtacttcaa attaaactat
    10081 tataccatag attaattcat tgtattgcaa atcaagttat tgtactatag attaaatcgt
    10141 tgtacttcaa atcatgctag tgtactataa attaaatcgt tgtactttaa attaaactat
    10201 tatactatag attaattcat tgttctgcaa atcatgctag tgtactacaa attaaactat
    10261 aaatgtttac tatctcttaa taatttgaat aatatgttac aaaaagtata gcaccttttt
    10321 atttttttcg caataaataa aaaatttaaa attttttatt ttttattttc ttatattatc
    10381 aatttgaaat acgaaagatt aagactaata gaattgattt agttaattga aaaaaatagg
    10441 taccttttat gaaaattcta atgataagta tttttctgat gtaatggtaa attataaatg
    10501 ataaaattaa aaatcacttt tagttttatg aactgtcccc atattaagaa acaactaaga
    10561 tacataaaaa tagttataaa gagatagtta aactatatcc actattttat atagttaaaa
    10621 tagtgagtat agtccaagct aagaataact aagaaattag cgttaaatag catagataaa
    10681 aatatattta tataaaaact ttttttgctg caaacaatta tttccataac attttatata
    10741 cttctctaaa atcttctaaa cttgataaat attcaattaa agggacataa ttacctaaac
    10801 tacaagaatt taaggagttt ctatacaatt cctcactatc ccaagataca atttttatag
    10861 gaagattatt ttctaacatc tgttttagca taacaaatct acctatgcga ccattaccat
    10921 cttgaaatgg atgtatcaat tcaaatctat aatgaaattc agctataact ttaatagata
    10981 cttcactctg actatagtac cattcaatta attcatcaag ctttggctca acttcaaatg
    11041 gttgtgcaat attattaaaa ctctaataat attaataata gctgatataa tagcaaatca
    11101 ttattatccc aagaagatac aattaataac taccttccta gccacagtat ctagtcaatt
    11161 tcagtaactt tatgatttag tatataatat ataccaatca cagttatacc aactataata
    11221 aaaacagaaa tcaaactgtc ttgagttgta tttgtaccag ctaaaataaa ttgtcttaaa
    11281 ttgataaaaa taattgaact gacaagggta acaggtattg attttcttat cattccaaca
    11341 actaatgtcc atatacctaa tgagcaaaat acaataatac ttttaattgc tcctggtatc
    11401 caataagata aaattgaaat atgaaaatct ccaataacta aattaaaata cttatccaac
    11461 acaacaacga atgtaaaaca acagatatat ccaactatca ttgatgatat cataagagtc
    11521 gtaatcaaaa gtaactttga taaaataagt tttttacggt caagtggata agagaataaa
    11581 atcaagattg ttttatttgt atattcattt attatatatg ccacattcaa cacagcaaat
    11641 aatataatat agtaaaaaca gaaaaataaa ctgattgtcc taaatgtaac atcataatca
    11701 tatattgaag tagatttatc attcaatcca gtaaagacaa aaaacataca taagaaaatc
    11761 cccagcattg aaaataaaaa atatcttttt agcccaactt tttttagctc tagtttcatt
    11821 aaatgtatca tagtgtttct ttacctcctg tacctgtagt ttggaagaag taatcttcta
    11881 aagaactttg tttacgtcca atgctattta taccaatttg attttgaata aatattttgg
    11941 atatttcttt tacatctttt cgtaaatcat atatttcaat acaactttcc gaagtaattt
    12001 taaagtcttt tattccaaat tctttttcta acaagtatcc agcaagctcc acattatcta
    12061 catctacttc aacataatct gtttgatatt tgtgtatatc tgacatagaa atttctttaa
    12121 taagtttacc atcttgaata attccaatag tgtccgcaat ttgttctacc tctgaaagaa
    12181 tatgactaga aataaatata gttattccat aatctgtatt taacttacgg aataattctc
    12241 gcatttctct tatcccctct gggtcgagtg catttatagg ttcatcaaga atcaataatt
    12301 ctggtttagt aagaattgct ctagctattg caagacgttg tttcatccct aaagaatatt
    12361 ttgaaacttt cttgtttgat tgctttgaca atccgacaca ttccaatacc tctgatatat
    12421 gttctttgtt ataataaccc atatattcac agtgtaaatc aagattctgt ttagcagtca
    12481 aattctcata taaatacgga ttttcaataa tagtaccaat cttttttaat atttcaaaat
    12541 cagtttctgc cactttctta ccgaacataa ctatttctcc agaatttgga ttaacaagat
    12601 ttagcaacat tttcattact gtacttttac ctgccccgtt tggtccaaca aatccataaa
    12661 tttctccctt tttcacatga atattaacag cattaacaac agctttatct ttatatattt
    12721 tctttaattg atgggtctct atgatatagt tcatcatact ccctcctttc taaaaacagt
    12781 atacaaaata aaattatctt ttctctcttt taaatctaac ttttttctaa cttttcaatt
    12841 ttaccgtaaa aactgttttt acattaggtc tactatttac ataaattgaa cctcccatag
    12901 agtttacaag cccttgagaa atagccaaac ctaaaccatt gccttttttt ctgtcagcag
    12961 tataagctct tgtgaaaata tgctcttttt cagtttcaga aatacctgaa cctttatcct
    13021 caatatctat aaaaacatgt ttttcctttt catatagtga aatccctaaa aatctaccat
    13081 ctgaaccata ttttatagca ttatcaatta aatttttgag tatacgttgt aatgcttctg
    13141 tgtcaacatt tgcatatata ggtctatctt caatattaac ttcaacatta aagttttctt
    13201 tatctagcaa atcataaaac tctaaaataa tctcatgaca taattgtgtt agattggatt
    13261 tttgaagatt taatatcata tctccagatt ggatttttgc catattaaac aggttattta
    13321 ttgaattaac aagctcattt gaatttgttt gcattttttc cacagttgct ctcattgaag
    13381 aagataattc ttctttttga ctttgaagat atagcatttc aatataaccc tttaatactg
    13441 tgatgggagt tcgtaaatcg tgtgatatgt ttgtaaatat ttgcaatatc gctttttcac
    13501 ttctattata attaatttgc ctgctgtaaa acttttcaac aagtttattt atatctactg
    13561 ctgtttcttt tacaatcgaa atatcagatg gtactaaaat ataattaatt tcatcatcat
    13621 ttgttatgtc acgaagtctt gaattgatat acttataatc actttccatt ttctttgatt
    13681 tatttcgttc ttttaagtag agagcaaata gtacaatcga aattacaact aaaaataact
    13741 ccattattct tcctccattt tgtagccaat tccccaaaga gttttaatat aattattttt
    13801 ttctatacca tcagacaatt tatttcttaa cctgttaata tgagtattta gcacattttc
    13861 atttccataa taaggttctt tccaaatagc gttgtataat tgttcctttg aaaaagcacg
    13921 tccttgatta gtcgctagta atttaacaat ttcaaattct gtatgtgtta agtttaagtc
    13981 aattccattc tttgaaacta catattttga tatgtttata atcaaatcct tataccgaat
    14041 aaccatatct tgagagtttc ttgaactgct atacactgtt gcacgtctaa tattagcttt
    14101 aattcttgca agcaattcta cgattgaaaa aggctttgta atataatcat ctgcacctag
    14161 attaagccct agcattttat ctgtgtcact atctttcgca gtagtaataa taacaggaac
    14221 aacactcaca cttcgtatat attttaatac ttcaaaacca ctagactttg gtaacatcaa
    14281 gtccagtaaa ataatatcaa atgaataatt tttaaatatt tcaatagctg tatttccatc
    14341 aatggcagtt ttaacagagt aattctcact aatcagaaaa tcgtatacca tttctcgaat
    14401 attcttatca tcttcaacca gtaagatgtc cattattatt caactccttt tcgtcagtat
    14461 acttcaaatg atatatttat taaaaagggt tgtcaataaa taactgctta tgatattgta
    14521 tctgcaattt ggtgatactc ttctaagtta aagttctttt caataagctt tattgaaaaa
    14581 agaattaaaa tatagtatac tctcttatct ttatctgaaa tatacataat tttcttttat
    14641 taacatctac aattaactat tttatattat aaaacacctt ttaacttttg ctaaaaaata
    14701 ttttatacat aaaaaagaaa ccacattcta gttttataca gaacatagtt tctttaaaaa
    14761 taatcaaatt tggattttaa ataattaaaa acaaactttt atttgttttt aattttccaa
    14821 ttttatagta gataatttag ttaattagtt cttaaatgtt tatcttcttt agtaaatttt
    14881 tttcttatta agaaatatgc aactattaca acaagttcta ttgctaaaaa tacaccataa
    14941 gtagctatag aatctatgct atctatgcca tttctaaaga aaattaaagc aattcctgct
    15001 gctataatac ctacagcatt tttccctata gaattttgac caaaaccata aaaagaaggg
    15061 aaatttcctt ttatttcaat gaatgtcaag attaatccaa tagctataaa tagtactcct
    15121 acaacttcca taatcatgct aggcattttg acccctcctt attaataatt aactactact
    15181 ataaaaatat ttattatttt t
//
LOCUS       DAFAZV010000073        14251 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFAZV010000073 DAFAZV010000000
VERSION     DAFAZV010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14251
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.075"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            277..558
                     /locus_tag="KOU88_003605"
     CDS             277..558
                     /locus_tag="KOU88_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213433.1"
                     /translation="MKEKYKWRKSTTEILLGRLVKMRILKKKRVGFQLNYEVLVTKKE
                     YLDVIKEEKDVSKYDNFFTQVFTTIHKKEEKTEEQIKVFIESMQKLGKK"
     gene            598..984
                     /locus_tag="KOU88_003606"
     CDS             598..984
                     /locus_tag="KOU88_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213434.1"
                     /translation="MLNKKLPDSEFKIMKYIWNTGYKTVISKDVADEMEKIYKWKQTT
                     TLTLLLRLTKRGFLASQKIGKHTHYTILIKEKEYLKSETKKLFGGLHNNPLSQLISKL
                     HDKEEVSIDKIDALEEWLRSLQEDEE"
     gene            1708..2154
                     /locus_tag="KOU88_003607"
     CDS             1708..2154
                     /locus_tag="KOU88_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213435.1"
                     /translation="MAISDLAFGTECLKTSFQMLFSVISLVNINLLQAQILIAIGGLI
                     SILAMVSLTLFLSAKCKDSLTSMLIAFSICLIPMGIGVSWIGYLLPPGGIGFKISLLY
                     QMTSFNFLHLGGMSFWTPHIILFFSVIEIPIFIFLAIRTYCKHQVS"
     gene            2535..3452
                     /gene="pstC"
                     /locus_tag="KOU88_003608"
     CDS             2535..3452
                     /gene="pstC"
                     /locus_tag="KOU88_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBK3213436.1"
                     /translation="MIVKSRLVGLEKNDNNGNKTKYVIEKVAKNIFLLSALVAVASLL
                     LIIGFVFYKGLRPFIFEGYSFIDFLTGADWVPSANKFGISSMIVASIFATLGALVIGV
                     PVGILTSVFIAEVAPKRLAKIMSPAVELLAGIPSVLYGVFGLAVIVPTIQSIFNLPKG
                     QSLLAIVIVLAVMMLPTIISVSETAIRAVPKAYKEGSLALGASKIETIFKVVLPAAKS
                     GVLAAVVLGVGRALGETMAVILVAGNSPVMPTAITDSVRPLTTNIALEMGYAFGTHQE
                     MLFATGVVLFTFILILNLVLNKLSNKAVN"
     gene            3454..4278
                     /gene="pstA"
                     /locus_tag="KOU88_003609"
     CDS             3454..4278
                     /gene="pstA"
                     /locus_tag="KOU88_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003460575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBK3213437.1"
                     /translation="MRKFKENLLKSLVYLSALFTIVSLVVIVGFIFIKGIGNMNFNFL
                     FSNYSASGDGGILPMIITTLYTVVVSIVVATPIGILAAIYLQEYAKKGKAVTAIRFAT
                     ESLSGIPSIVYGLFGGIFFVVTLKMGYSIVAGSLTVAIIILPVIIRTTEEALKTVPQA
                     YRESSLALGATKFQTLYKVVLPSAIPGILSGVILSVGRIIGESAAILLTAGTVAKMPG
                     GIFDSARTLTVHSYLLTKESGDIATAASIGIVLIVIVLALNMLARFVAKKLNKANY"
     gene            4297..5061
                     /gene="pstB"
                     /locus_tag="KOU88_003610"
     CDS             4297..5061
                     /gene="pstB"
                     /locus_tag="KOU88_003610"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBK3213438.1"
                     /translation="MELIDKIKMSVKDLDLFYGDKQALKKINMDIKENKVTALIGPSG
                     CGKSTFIRTLNRMNDLIEDVTIKGNISVDGEDIYTSDDVINLRTKVGMVFQKPNPFPM
                     SIYDNVAYGPRTHGLRDKKQLDKIVEESLKGAAIWDEVKDRLKSSALGLSGGQQQRIC
                     IARAIAMRPEVILMDEPTSALDPISTLKVEELIEDLKKDYTIVIVTHNMQQAARISDE
                     TAFFLNGEVIEFSDTKTMFTTPVDKRTEDYITGRFG"
     gene            5089..5742
                     /gene="phoU"
                     /locus_tag="KOU88_003611"
     CDS             5089..5742
                     /gene="phoU"
                     /locus_tag="KOU88_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBK3213439.1"
                     /translation="MVNNSLDISIDTLKEQTVLMMEKCEEAIEKSVTCMIEKDLEGAR
                     KVVEDDEEINKLREEIRDKSIELIVLKQPMARDLRFIYSLGNISIELERIGDYAANIA
                     REMLKIGGEAYIKELIDIPKMAKECKSMMSQTREALILFDASIAYDVGTKDDIVDGLY
                     EQVQIDCLKIMHENSNTIDQGVKLLLIGRYLERIGDHITNVCEKIIFAIEGKMVEIG"
     gene            5900..6769
                     /locus_tag="KOU88_003612"
     CDS             5900..6769
                     /locus_tag="KOU88_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK3213440.1"
                     /translation="MKLQKMGMRTIKTGISVTLCMILGDYLVENMFYSLVACIISVQD
                     TVKGSLKTGINRVEGTILGGIIGFIFAIIKAGDPFLCGLGVMCSIYLCNLFKIKSVVV
                     ACVTFLAIHLGVGNSDPVYYSLHRVLDTSVGVLFGVLVNYYVARPNYLNSVIDEFKKI
                     EELSMLLIEDKILRKENLNVEKFEEEVEKLEEIYSKLIDELDYSLSETNIEKIENALR
                     ICREIHFHMQSIELLENKLYLKEHTYKYLKKTYNVDKLDWNIDEEKSPVFNYHLMKIM
                     IEIELLRKLNKSY"
     gene            6856..8292
                     /locus_tag="KOU88_003613"
     CDS             6856..8292
                     /locus_tag="KOU88_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron hydrogenase"
                     /protein_id="HBK3213441.1"
                     /translation="MNTRNDNSKILEIYKMKLFGELVKAVWNDDIEDIENLPNKILNE
                     DLKDNLNNYFSGKFDKDTMVNLIRVTMGLDVTEDTDKNLKESLHEAVNLDEVKRPIIS
                     VISDACKYCDENNKEDESCKIRSKHINCNEEDVCSACGDCVSRCKLGAISDKIEFIPM
                     IKLLKDIKSPVYAIVAPAFVGQFGKDVSPGKLRTALKKIGFEDMIEVALAADMLTAKE
                     AYDYYEHMKKDEEGCFITSCCCPIWVSLIQNSFPQILENVSPSVSPMIACGRAVKILN
                     PDAKVVFIGPCMAKKKEAMLEDIKDAVDFVLTFKELQEIFDALELNPAIMDESNRVEA
                     SLSGRVYARTGGVSKAVKLSVRRIDKNIKFEEKAFEGTKECMDGLKKVLNKEIEATFI
                     EGMGCVGGCVGGPKRILSVEEGTKNVDEYSESTNMETPFDNLNVLQFLTSLGIKRVES
                     LGEKEEEKVKKIFSRDIKSNKKENKYKK"
     gene            8340..9167
                     /locus_tag="KOU88_003614"
     CDS             8340..9167
                     /locus_tag="KOU88_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK3213442.1"
                     /translation="MKIKDNKAVFHVFIRIFIIAVLILTGTLLEEKINNVPVENISSK
                     GENTLELLSQSNTLGEIIYKASQEETKGPGATSEKVAYITIDDGPSKYTNALLDILKE
                     NDVKATFFMLNQNMKNHKEEVRRVLEEENSIGFHSVSHDIHKLYKSPEVTVGEFNTCN
                     NTLQEITGQSSKLIRLPYGSKPYMPEGSYNKLMANDYLIWDWNLDTQDWKSSTSQIVS
                     NILYYGRKRDELVVLIHEKEQSLNALNNIIRILKERGYTILPITENITPKNFWQENL"
     misc_binding    9468..9730
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            9806..12472
                     /locus_tag="KOU88_003615"
     CDS             9806..12472
                     /locus_tag="KOU88_003615"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBK3213443.1"
                     /translation="MENTNLSKTYNPKDFEARLYKKWMDEGYFKSKPNPDKKPFTIMM
                     PPPNITGQLHMGHALDHTLQDILIRWKRMDGYEAFWLPGTDHASIATEVKVVERIKKQ
                     EGKTKYEIGREEFLKRAWEWKDEFGGKISNQLKQLGDSCDWDKERFTMDEGCNEAVIE
                     FFVSLYEKGHIYRGNRIINWCPDCKTTLSDAEVEHEEHDGNFYHIKYPLKDSEDFLEI
                     ATTRPETMIGDTGIAVNPEDDRYKHLIGKTAILPLVGRELPIVADSYVDLEFGTGAVK
                     MTPAHDPNDFEVGLRHNLEQLNTMNEDGTMNEVCGKYEGMDRFECRKAIVADLKEQGY
                     LIKIKEHNHNVGTCYRCHTVVEPRLSEQWFVKMEELAKPAIDILKKGELEFVPDKFDK
                     TYLQWLENIRDWCISRQLWWGHQIPAYYCQECGEIVVARKMPDKCPKCGSTHFKQDED
                     ALDTWFSSALWPFSTLGWPNKTEALDYYYPTSVLVTGYDIIFFWVVRMAFAGMFCMNE
                     KPFDHVLVHGLVRDSQGRKMSKSLGNGIDPLEIIEQYGADALRFTLTTGNSPGNDMRF
                     YMERVEFARNFANKLWNASRFVFMNIDEDIIKNMTRESVKEDLTLADKWIISRANNIV
                     KEATNNMDKFDLGIALQKIYDFTWSEYCDWYIEMVKPRLYGEDANAKSAALYTLTYVL
                     EKILKLLHPYMPFITEEIYTHLPTVEGCIIVSEWPKYNEEDNMAEEEDMMNLLMEGIR
                     SIRNVRAEMNVPPSKKAKLIIIPSEEKIEAIELGKDYFITLASASNVEIAKDKSNVPE
                     DAVGVVIDGVEIFIPLNELVDFEKEIERLSKEKKKLEGEIKRVNGKLANQGFLAKAPE
                     SLIEEEKAKKEKFEEMIKSVEERLTNLESKIK"
     gene            12897..13607
                     /gene="rgaR"
                     /locus_tag="KOU88_003616"
     CDS             12897..13607
                     /gene="rgaR"
                     /locus_tag="KOU88_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RgaR"
                     /protein_id="HBK3213444.1"
                     /translation="MFRVVICDDEKIQRSILKEFTEKLLSERCLNYQILEFSCGEDLI
                     SKYPEKIDIIFLDIQMKDINGIEVAKKIRKFDEKVEIIFTTAFSEYAPQGYEVRAYRY
                     LVKPIEYSNFAMGVNLCIDNLQRKKERYIVLNSKKGFNRILIDSILYVETVKRDLVVH
                     TIGRDYKANMSMKQAEKLLCENGFFRCHTSFIVNLRRIEDLRDNMITINEQFIPISKY
                     RLKDLKVALTSLLCDIMY"
BASE COUNT         5714 a         1434 c         2543 g         4560 t
ORIGIN      
        1 ttcaacaaga ttgtttgaaa attaaataaa tttgtagatg tgaataatat tttttatata
       61 taaaaacaaa ctaaaacagt agaatatatg gtaaaaatta cctatagttt ttgttctaaa
      121 aagctcctat tattaattta agttagacga attaaggaag tgacataaat ggagcgacaa
      181 gaggtagaaa gtaaattacg caggggcgaa ttaatgttga tggagtacat gtgaagggaa
      241 aagtctactc tatctaaaaa agaaatagaa gtagcaatga aagaaaagta taagtggaga
      301 aaaagcacta cagagatttt acttggaaga ttagtaaaaa tgagaatatt aaaaaagaag
      361 agagttggtt ttcaattaaa ctatgaagta ttagtaacta aaaaagaata tttagatgta
      421 ataaaagaag aaaaagatgt aagtaaatat gataattttt ttacacaagt atttacaact
      481 atacataaaa aagaagaaaa gacagaggaa caaataaaag tatttataga aagtatgcag
      541 aaactaggaa aaaaataatt ttatattttt atatgttaat agaaagaagg ggatattatg
      601 ctaaataaaa aattaccaga ttcagagttc aagattatga aatatatttg gaatactggt
      661 tataaaactg taatatcaaa agatgtggca gatgaaatgg aaaaaatata taaatggaaa
      721 caaactacaa cactaacact tttattaagg ttaactaaaa gaggtttttt agcttctcaa
      781 aaaataggta aacacacaca ttatacaata ttaataaaag aaaaagaata cttaaaatca
      841 gaaactaaaa aactatttgg aggtttacat aataatcctt tatcacagtt aatatcaaaa
      901 ttacatgata aagaagaggt aagtattgat aaaatagatg cgcttgaaga atggttaaga
      961 agtttgcaag aagatgaaga ataagaatat gccaaaaggt agcactcaat agtagctacc
     1021 tttttgtgga taaagctggg gataaactat ggaaaagtta tataaaaatt gtggataaaa
     1081 tgttttgctg acatttaact gacataaata ttaaaacttg attttaaagt attgaaattt
     1141 caattattaa tcatataaaa atagaaaagt tattatttta ataaagaata ataaatatat
     1201 taatatcatt aataattgtt ataaatgtga aatactaacg atatctaaac taaattatta
     1261 taaaatagct gactgtaatt taattgataa agcctattct tctagacttt gccaattaaa
     1321 ttacagtcag ttttattata taaaaaaatg cgtaacagaa ctattatttt atagattata
     1381 tttgaaaaga taaataaatt gtatatctaa atctatatat tattttttac ctttaatata
     1441 tattaaataa taaaatagtt aaataataag attaagaatt tcttaataaa tccagaagat
     1501 gctttcgatt atataatatt ttatattttt atattattaa ttatatgtgt tgcaattgct
     1561 gcacctactt tttctggtga gtatcagaca caatcagata gcatccttcg ttgtacgaaa
     1621 catggacata ttcgtctagc gtttactaaa atattagctc tattttctat atttataata
     1681 atgtttgtta tatgtatttc tatccatttg gcaatttctg atttagcttt tggtactgaa
     1741 tgtttgaaaa cctcatttca aatgttgttt tctgtaatta gtctagtaaa tataaattta
     1801 ctacaagcac agattcttat agctattggt ggtctaattt caatacttgc aatggttagt
     1861 ttaacattat ttttatctgc aaaatgtaag gattctctta cttctatgct gattgctttt
     1921 tctatttgct taattcctat gggaataggt gttagttgga ttggatacct attaccacca
     1981 gggggaattg gttttaagat tagtttatta tatcaaatga catcatttaa tttcttacac
     2041 ttaggaggta tgagtttttg gacaccacac attatactgt ttttctcagt gatagaaata
     2101 cctattttta tatttttggc tattcgtacc tattgcaaac atcaagtatc gtaacaattt
     2161 gatggaaata atagtgatat aaactagagg atacaataat tatatatgta gtataaaagt
     2221 taaatttagt taacaaatct taatagcaga tataggtaat aaattataca taaactgtat
     2281 tattatctat atctgctatt ttaatataga gaaacaacag tatattgtaa agtaaatgtc
     2341 aaatatagtt ttaaaagtaa aattaatgtt aaaaagtaaa tataatttta cacttgctta
     2401 acttaatcct aatatagatt taacttaaaa aaagtagaat aaaagtatag gaaatttgat
     2461 gaagacgaat tataaaaaat taaattttga atacagaacg aaaatcgata agtatatttt
     2521 aatgggaggg tattatgata gtaaaatcta gattagtagg tttagaaaaa aatgacaata
     2581 atggcaataa gacaaaatac gtaattgaaa aagtagcaaa aaatattttt ctacttagtg
     2641 ctttagtagc agttgcaagt ttacttttga taataggatt cgtattttat aaaggattaa
     2701 gaccatttat atttgaagga tattcattta tagacttttt aactggtgca gattgggttc
     2761 cttctgccaa taaatttgga atatcatcta tgatagtagc atcaatattt gcaacacttg
     2821 gagcacttgt gataggagta cctgttggta tattaacctc tgtatttata gcagaagtag
     2881 cacctaaaag attagcaaaa ataatgtcac cagcagttga acttttagca ggtatacctt
     2941 cagtattata tggtgtattt ggtcttgcag tgatagttcc aactatacaa agtatattta
     3001 atcttccaaa aggtcaaagt ttgttagcaa tagtaatagt attagcagta atgatgttac
     3061 caacaataat atctgtatca gaaacagcaa taagagcagt accaaaagca tacaaagaag
     3121 gttcattagc acttggtgca tcaaaaatag aaacaatatt caaagttgta ttacctgctg
     3181 caaaatctgg agtattagcc gcagtagtgt taggagtagg aagagcttta ggtgaaacaa
     3241 tggcagtaat acttgttgca ggcaactcac cagttatgcc aactgcaata acagatagtg
     3301 taagaccact tacaactaat atagcacttg aaatgggata cgcatttggt acacatcaag
     3361 aaatgctatt tgcaactgga gtagtattgt ttacatttat attaatttta aacttagttt
     3421 taaataaact ttcaaataag gcggtaaatt aagatgagaa agttcaaaga gaatctattg
     3481 aagtcattag tatatctatc agcactattt acaatagtat cattagtagt tatagtggga
     3541 tttatattta taaagggaat tggcaacatg aattttaatt tcttatttag caattattca
     3601 gcatcaggtg atggtggtat acttccaatg ataattacaa cattatatac agtagtggtt
     3661 tctatagttg tagcaactcc tataggaata ttggctgcta tatatttaca agaatatgct
     3721 aaaaaaggaa aagcagttac agctataaga tttgcaactg aaagtttatc agggatacca
     3781 tctatagtat atggattatt tggaggaatt ttctttgtag ttacattaaa aatgggatat
     3841 tccatagttg caggttcact tacagttgca ataataatat taccagtaat aattcgtaca
     3901 acagaagaag ctttaaaaac agttcctcaa gcttatagag aatcatcatt ggcattagga
     3961 gctacaaaat ttcaaacttt atataaggta gtacttccaa gtgcaatacc aggaatttta
     4021 tctggagtaa tcttatcagt tggtcgtata attggagaat cagctgcaat attacttaca
     4081 gcaggtactg tagccaagat gccaggtgga atatttgata gtgcaagaac attaactgta
     4141 cactcatact tactgactaa agagagtgga gatatagcaa cagcagccag tataggaatt
     4201 gttttaatag taattgtatt agcactaaac atgctagcaa gatttgttgc taagaaatta
     4261 aataaagcta attattaaat ttaagaggtg tgaataatgg aattaatcga taagataaaa
     4321 atgagtgtaa aagatttgga tttattttat ggtgataagc aagcattaaa gaaaataaat
     4381 atggatataa aagagaataa ggttactgct ttaataggtc catctggatg cggaaaatca
     4441 acttttataa gaacgttaaa tagaatgaat gacttaatcg aagatgtaac aattaaagga
     4501 aacatttctg ttgatggaga ggacatatat acctcagatg atgttataaa tcttcgtact
     4561 aaagtaggaa tggtatttca aaagccaaat ccatttccta tgagtatata tgataatgtg
     4621 gcatatggtc ctcgtacaca tggactaaga gataagaagc aattagataa aattgtagaa
     4681 gaaagcttaa aaggtgcagc tatttgggat gaggttaaag acaggcttaa atcatctgca
     4741 ctaggacttt ctggtggtca acaacagcgt atatgtatag caagagcaat tgctatgaga
     4801 ccagaagtta ttcttatgga tgaacctaca tctgctttag acccaatttc aacattaaaa
     4861 gtagaggaac ttatagagga tttaaaaaaa gactacacaa tagtcatagt tacacataat
     4921 atgcaacaag ctgctcgtat atcagatgaa acagcttttt tcttaaatgg agaggttata
     4981 gaatttagcg atacaaaaac tatgtttacc actcctgtag ataaaagaac agaagactat
     5041 ataacaggta gatttggtta aaatatataa ctataaagga gttagacaat ggtcaataat
     5101 agtttagata taagtattga tactttaaaa gaacaaacag tgcttatgat ggaaaaatgt
     5161 gaagaagcaa tagaaaagtc tgtgacttgt atgatagaga aggatttaga gggtgcaaga
     5221 aaagtagtag aagatgatga agaaataaat aaattaagag aagaaataag agataagagt
     5281 atagagctaa tagtattaaa gcaaccaatg gcaagggact taagatttat ttattcatta
     5341 ggtaatatat ctatagagct ggaaagaata ggagattatg cagcaaatat agctagagaa
     5401 atgttgaaga taggtggaga ggcttatata aaagagctaa tagatattcc taagatggca
     5461 aaagaatgta agtctatgat gtctcagact agagaagctt taatcttatt tgatgcaagt
     5521 atagcttatg atgttggaac taaagatgat attgtagatg gattgtatga acaagtacaa
     5581 attgattgtt taaaaataat gcatgaaaac tcaaatacca tagaccaagg tgtaaaactt
     5641 ctacttatag gaagatacct tgaaagaatt ggagaccata taacaaatgt atgtgagaag
     5701 ataatttttg caattgaggg taaaatggtt gagataggat aaaaaactgc tttaaagcag
     5761 tttttttatt gtctaaatta agaaagaatt gataaaaaaa tatgattaat gggtaaattt
     5821 aaaaaattgt gatatactag gaacatatta aatatgagga tgcgtatttt atataaggtg
     5881 ctttttagga ggtggaactt tgaaacttca aaagatgggt atgaggacta taaaaacagg
     5941 aattagtgtc actttatgta tgattcttgg tgactattta gtagagaata tgttttattc
     6001 tctggtagca tgtataattt ctgttcaaga tacagtaaaa ggttctttaa agacgggaat
     6061 caatagagtg gaaggtacta ttttaggtgg tataatagga ttcatatttg caatcattaa
     6121 agctggagac ccatttttat gtggtctagg agtaatgtgc tcaatatatt tatgcaatct
     6181 gtttaaaata aagtcagtag tagttgcctg tgtaaccttt ctggctatac atctaggtgt
     6241 aggaaatagt gaccctgtgt attattcttt acatagggtg ttagatacat ctgtgggtgt
     6301 tttgtttgga gtacttgtta attattatgt tgctagacca aattatctaa atagtgttat
     6361 agatgagttt aaaaagatag aagaactttc aatgttgctt attgaagata aaattcttag
     6421 aaaagaaaat ttaaatgtag agaaatttga agaagaagta gaaaaattag aagaaatata
     6481 ttcaaaactt attgatgagt tggattatag tttgagtgaa actaatatag aaaaaattga
     6541 gaatgcctta aggatatgta gagaaataca ttttcatatg cagtctatag agttacttga
     6601 aaataaactt tatttgaaag agcatacata taaatacctt aagaaaacat ataatgtgga
     6661 taagctagac tggaatatag atgaagaaaa aagccctgta ttcaactatc atctaatgaa
     6721 aataatgatt gaaatagagt tgttgagaaa gctaaataaa tcatattaat aatagtagtt
     6781 aaataataaa taaaaaatag tatctttgta aatattaaac atatataagt ttaatttatg
     6841 gaggtactat tttttatgaa tactagaaat gacaattcta aaatactaga aatatataaa
     6901 atgaagcttt ttggcgaact tgtaaaagca gtgtggaatg atgatataga ggatattgaa
     6961 aacttaccta ataaaatttt aaatgaagat ttaaaggata atttaaataa ttattttagt
     7021 ggaaaatttg ataaagatac tatggtaaat ttaattaggg taactatggg attggatgtg
     7081 acagaagata cagataaaaa tttaaaagag tcactacatg aagctgtaaa tttagatgaa
     7141 gtcaaaagac caataatatc tgtaatatca gatgcttgca aatattgtga tgaaaataat
     7201 aaggaagatg agtcatgtaa gataagaagt aagcatatta attgtaatga ggaagatgta
     7261 tgtagtgctt gtggtgattg tgtatcaaga tgtaagttgg gtgcaatttc agataaaata
     7321 gaatttatac caatgataaa attgttaaaa gatataaaga gccctgtata tgcaatagtt
     7381 gcaccagctt ttgtaggaca gtttgggaaa gatgtaagcc ctggtaaatt aagaactgca
     7441 ttaaaaaaga taggatttga agatatgata gaagttgctt tggcagcaga tatgcttact
     7501 gcaaaagaag catatgatta ttatgagcat atgaaaaagg acgaagaagg atgctttata
     7561 actagttgtt gctgtcctat ttgggttagt ttgatacaaa atagttttcc tcagatattg
     7621 gaaaatgtat caccatccgt ttctcctatg attgcttgtg ggagagctgt aaaaatttta
     7681 aatccagatg ctaaagttgt attcataggt ccttgtatgg caaaaaagaa agaggcaatg
     7741 ttagaagata taaaagatgc agttgatttt gtgcttacat ttaaagagtt gcaagaaata
     7801 tttgatgcat tagagttaaa tccagcaata atggatgaga gtaatagagt agaggcgtcc
     7861 ctttcaggta gagtttatgc tagaacagga ggtgtaagta aagcagttaa gttatcagtt
     7921 agaagaattg acaaaaatat aaaatttgaa gaaaaggcat ttgaaggaac aaaagagtgc
     7981 atggacggtc taaagaaagt tctaaataaa gaaatagaag ctacatttat agaaggaatg
     8041 gggtgtgtag gaggctgtgt aggaggtccg aagcgtattt taagtgtgga agaaggtact
     8101 aagaatgttg atgaatatag tgaaagtacg aatatggaaa ctccatttga taatttaaat
     8161 gtattacaat ttttaacttc tttgggaatc aaaagagtag aatctttagg agaaaaagaa
     8221 gaagaaaagg ttaaaaaaat atttagtaga gatataaaaa gtaataagaa agagaataaa
     8281 tataaaaaat aactttttaa gtcttaaact tatgctttta taaaagggag atatggggga
     8341 tgaaaattaa agataataag gctgtttttc atgtatttat aaggatattt attatagctg
     8401 ttttaatttt aactggaaca ttattggagg aaaaaattaa taatgttcca gttgaaaata
     8461 taagttcaaa aggtgaaaat acactggaac tgctttctca aagtaatact ttaggagaaa
     8521 tcatatacaa agcatctcaa gaagaaacaa aaggtccagg ggctacttct gaaaaagtag
     8581 catacataac aatagatgat ggtccatcaa aatatacaaa tgcactactt gatattttaa
     8641 aagaaaatga tgtcaaagcg acatttttca tgcttaatca gaatatgaaa aaccacaagg
     8701 aagaagtaag gagagtcttg gaagaagaaa actcaatagg ttttcatagt gtaagtcatg
     8761 atatacataa gttatataaa agcccagaag taacagttgg ggaatttaat acatgcaata
     8821 atactctaca agaaataact ggtcagagtt caaaattaat aagattacca tacggaagta
     8881 aaccatatat gccagaaggt tcatataata aacttatggc aaatgattat ttaatttggg
     8941 actggaattt ggatacacag gattggaagt cttctacaag tcagatagta agtaatatat
     9001 tatattatgg aagaaaaaga gatgaattag tagtattaat tcatgagaaa gagcaaagtt
     9061 taaatgcttt aaataatatt ataagaatct taaaagagag aggatataca atattgccaa
     9121 ttacagaaaa tataacacct aaaaatttct ggcaagaaaa cttataataa atttaaatat
     9181 agtaaaagat aaagtaaatt atttataaaa taaaacatat aatataaaaa atacgaataa
     9241 gaggtatact gtaaggataa tataatataa aattaatgag aaagcattaa aattaaaata
     9301 aaataatctt gcaattattg acattataag acagaataac tgtaaaaaca tattttaaaa
     9361 tataacaact atataaaaga gaatagacat aattaagaaa attcagaaaa aataaaataa
     9421 aaataattga caaagagaat aatatttgta tataataata tgtaatatta aagactgaga
     9481 agaagaggag taagtaaata ctactaaaag agaggaaaat tcactggctg taagattttc
     9541 taagtataag atttactgaa tgtagctttg gagtttctaa actgaactat aagtaagttt
     9601 agacggttag aaccgttaaa ttctttgaga gtcaaagttg ataaaataac attaaccaat
     9661 aatttaatta tatgttaatg tattttaagc tttggaatta aggtggtaac gcgagctttt
     9721 cgtccttttt aaagaggatg aagagctctt ttttatttct aaagatattt aaaaaattta
     9781 tttataaaat acaggaggca ggacaatgga aaatacgaat ttatcaaaaa cttataaccc
     9841 aaaagatttt gaggctaggc tatataaaaa atggatggat gaagggtatt ttaaatctaa
     9901 accaaatcca gataaaaaac catttacaat aatgatgcca ccaccaaata taacagggca
     9961 attgcatatg ggacacgctc ttgaccatac acttcaagat atattaatca gatggaaacg
    10021 tatggatgga tatgaagctt tttggcttcc aggaactgac catgcttcta tagcaacaga
    10081 agttaaagtt gttgaaagaa taaaaaaaca agaaggcaag acaaagtatg aaataggtag
    10141 agaagaattt ttaaagagag cctgggaatg gaaagatgaa tttggaggaa aaatatctaa
    10201 tcagcttaaa caactaggtg attcttgtga ttgggataaa gaaagattta ctatggatga
    10261 agggtgtaat gaagcagtta tagaattttt tgtaagccta tatgaaaaag gtcacatata
    10321 cagaggaaat agaataataa actggtgccc agattgcaaa actactttat cagatgcaga
    10381 agttgaacat gaagaacacg acggaaactt ttatcatata aagtacccac taaaagatag
    10441 tgaagacttt ttagaaatag ctacaactag acctgagaca atgataggag atactggtat
    10501 agcagtaaat ccagaagatg atagatataa acatttaata ggaaaaacag caatacttcc
    10561 attagtagga agagaacttc caatagttgc agatagttat gttgatttag agtttggaac
    10621 tggtgcagtt aagatgactc cagcacatga ccctaatgat tttgaagtag gattaagaca
    10681 taatcttgag cagttaaata ctatgaatga agatggaact atgaatgaag tttgtggaaa
    10741 atatgaaggt atggatagat ttgagtgtag aaaagctatc gtagcagact taaaagaaca
    10801 aggttaccta attaagataa aagagcataa tcataatgta ggaacttgtt atagatgcca
    10861 tacagtagtt gagcctagat tatcagagca atggtttgtt aagatggaag aacttgcaaa
    10921 accggctata gatattctta aaaaaggaga attagaattt gttccagata aatttgataa
    10981 aacttattta caatggctag aaaatataag agattggtgt atatcaagac aattatggtg
    11041 gggtcatcaa ataccagctt attattgtca agagtgtgga gaaatagtag ttgctagaaa
    11101 aatgccagat aagtgtccta aatgtggaag cactcatttt aaacaagatg aagatgcttt
    11161 agatacttgg ttcagttctg cattatggcc tttctctact ctaggatggc caaataagac
    11221 tgaagcttta gattattatt atccaacaag tgtacttgtt acaggatacg atataatatt
    11281 cttctgggta gttagaatgg catttgcagg tatgttctgt atgaatgaaa agccatttga
    11341 ccatgttttg gttcatggat tagtaagaga ttctcaaggt agaaaaatga gtaaatcttt
    11401 aggaaatggt atcgacccat tggagataat cgagcaatat ggagctgatg ccctaagatt
    11461 tacattaaca actggaaatt ccccaggaaa tgatatgaga ttctatatgg aaagagtaga
    11521 atttgctaga aactttgcaa ataagttgtg gaatgcatca agatttgtat ttatgaatat
    11581 tgatgaagat ataattaaaa acatgactag agaaagtgtt aaagaggact taactctagc
    11641 tgataaatgg ataatatcaa gagcaaataa tattgtaaaa gaagcaacta ataacatgga
    11701 taagtttgat ttaggaatag cacttcaaaa gatatacgat tttacttggt cagaatactg
    11761 tgactggtat attgaaatgg ttaaacctag attatatgga gaagatgcaa atgctaaatc
    11821 tgcagcatta tatacattaa cttatgttct tgaaaaaata ttaaaattat tacatccata
    11881 catgccattt ataacagagg aaatatatac tcatcttcct actgttgaag gatgtataat
    11941 agtatctgaa tggccaaaat ataatgaaga agataacatg gctgaagaag aagatatgat
    12001 gaacttattg atggaaggta taagaagtat aagaaatgtg agagcagaaa tgaatgtacc
    12061 accttctaag aaagctaaat tgataataat cccaagtgaa gaaaaaatag aagctattga
    12121 gcttggtaaa gactatttta taactttagc atctgcttca aatgtagaga tagcaaaaga
    12181 taaatctaat gttccagaag atgcagttgg agtagttatt gatggtgttg aaatatttat
    12241 acctcttaat gaattagttg attttgaaaa agaaattgag agattatcta aagaaaagaa
    12301 aaagttagaa ggcgaaataa agagagttaa tggaaagctt gcaaatcaag gtttcttagc
    12361 aaaagctcct gaaagtttaa ttgaagaaga aaaagcaaaa aaagaaaaat ttgaagagat
    12421 gattaaatct gttgaggaaa gattaacaaa tttagaatct aaaataaaat aaatataaga
    12481 attagtaaaa acatacaaaa agtatatatt ctatactttt tgtatgtttt tctttatata
    12541 tatacaaata tgatgttata attctttaca gatgtgttat atttttattt tatgttgtga
    12601 atatatgaat tttatgtctt aaaatttata agcaataaaa atttgatata ttatgatgtt
    12661 taatataggg taataaatac atattatatt tattttacta tattttttta cataatatat
    12721 ctagaaaagt ataggaattt atcgtaattt aagtttaaat attaaagaga atttctataa
    12781 gtagtttaat cgacaattta aatttataaa gaaatttaaa tttgaaagct agtgagtaca
    12841 gtttggaaat tgaaataaag taaactaaat gatattttag atttggaggt gatattatgt
    12901 tcagggtagt tatatgtgat gacgaaaaaa tacaaagaag catactaaaa gagtttacag
    12961 aaaaactttt gtctgaaaga tgtctaaatt atcaaatact ggaattttcc tgtggagaag
    13021 atttaatatc caaataccca gaaaaaattg atattatatt tttagatatc caaatgaaag
    13081 atatcaatgg aattgaggtg gctaaaaaaa taagaaagtt tgatgaaaaa gtagaaatta
    13141 tatttacaac ggctttttca gagtatgccc cccaaggtta tgaggttcgt gcttatagat
    13201 atttagtaaa gcctatagag tatagtaact ttgcaatggg tgtaaatctt tgtattgata
    13261 accttcaaag aaagaaggag cgttatatag ttttaaatag taaaaaagga tttaatagaa
    13321 tactgataga ttctatttta tatgttgaaa ctgtaaagag agatttagtc gtacatacaa
    13381 taggtagaga ttataaagct aatatgagca tgaaacaagc agaaaaatta ctgtgtgaaa
    13441 atggcttttt tagatgtcat acaagtttta ttgttaattt aagaagaata gaagatctta
    13501 gggataatat gattactatt aatgaacaat ttatacctat aagtaagtat agacttaaag
    13561 atttaaaagt agcattaaca agcttgttat gtgatataat gtattaattt taaaaaggta
    13621 attgaaaata tcgtaaaaaa gatttaatgt catcacaggg ctattgattg aaactgtctt
    13681 aatatataaa atgttattta tattaagaca gttttattat gcaaaatagt agtttataga
    13741 tttttaatat ggtttaacat gtatatgtag agtttccatt ataatagcat gattattaat
    13801 tagtagcttg attatcaata tactattatt gatttttata tgcattatat gtatttttag
    13861 aatatgatta cctttttaaa ataatgacta tttataaaac tctatagata tttgtttcat
    13921 ttagctacgc atactttaat taattatatt aatatttaat ggagtacaat ataaatatta
    13981 aagcgacatc ttatagttta ttgaacctat agtaatgaat taataaatag tttaattcta
    14041 tgaaaagatt tccttttatg caatttattt attgaaatat gatataatat ataaaggtgt
    14101 aagtattagt tgttaaaata atatttatat tagtttttat acatacttgg tataagtttt
    14161 tcatatattg attaaaattg atgttgattt attattttta gtattttttc accttttgat
    14221 tcatactttg tagaatggtg tattttctaa a
//
LOCUS       DAFAZV010000074        14195 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFAZV010000074 DAFAZV010000000
VERSION     DAFAZV010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14195
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.076"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            122..1045
                     /locus_tag="KOU88_003617"
     CDS             122..1045
                     /locus_tag="KOU88_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBK3213445.1"
                     /translation="MVGAFVLPNYAITLSEMSNLWGNFTMWILVPIITIVLLIIAVSS
                     MQYILVMIAFLLIIYSFIEKKIVMALVSVLFFTYSIYLCATWKDKSLIADNKVETVKA
                     QRETVEREKEMERRRIQEEVDKERYIEKHGMEISENDLKVKLEALVPQEYKGKKYELK
                     VEKFKRYSMYFDLTVQNEKFSNSEECKKFVKEIANDLKKIKISKAYFKFHSKDDGGIY
                     NSVYIDYFRNIQNNVDNVENLEFNEFELKTEEEEKREQEKIEQEKNSYNNYIQNRVVD
                     PLDRIKKLKELLDSGAITQEEYNKKKKELLE"
     repeat_region   1312..2059
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=1312..1340
                     /rpt_unit_seq="gttttagattaactatatggaatgtaaat"
     gene            2250..2402
                     /locus_tag="KOU88_003618"
     CDS             2250..2402
                     /locus_tag="KOU88_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213446.1"
                     /translation="MKNCRKDKRGFSVLLDKEKLDKFDEVLEEKNLTKKEWLEEKIDE
                     ELEQKE"
     gene            2522..3335
                     /locus_tag="KOU88_003619"
                     /pseudo
     CDS             2522..3335
                     /locus_tag="KOU88_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
     gene            3387..3548
                     /locus_tag="KOU88_003620"
     CDS             3387..3548
                     /locus_tag="KOU88_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213447.1"
                     /translation="MCENLLDNMYIEKRKEEYRIKLLKIRETDIDIYNKLESIVYKLS
                     EKKLEKNNK"
     gene            complement(3876..4340)
                     /locus_tag="KOU88_003621"
     CDS             complement(3876..4340)
                     /locus_tag="KOU88_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213448.1"
                     /translation="MDFGEVKSELSDKDLKDNEEALNKYKKYYLKVYKYYSEMDSIKS
                     IQDIEIEQSRLKGQLQKNSNPIFALYISIMAVVFSTTINLTFDLSDITNYFIRMIMTL
                     LFIVLLIFLVNKGILPIAIPYRNNIQFYTTALDVLEDMKNKILRERKYKKRR"
     gene            complement(4476..4793)
                     /locus_tag="KOU88_003622"
     CDS             complement(4476..4793)
                     /locus_tag="KOU88_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213449.1"
                     /translation="MDFGNINLILIGIIVIIGTTIIYLIKPKTAFCSKKYFNKLESIY
                     GNIDKKKTVKLEVLYRYVTGLEYIAIGLFTRRLDITIIAIILVAIITTALYYLIRKKY
                     ITI"
     gene            complement(5076..5372)
                     /locus_tag="KOU88_003623"
     CDS             complement(5076..5372)
                     /locus_tag="KOU88_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213450.1"
                     /translation="MYFKTYILKREVNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPPARECLVIAIEVYWWYTSIFLLYHINYVIKKNYLNRF"
     gene            complement(5391..5804)
                     /locus_tag="KOU88_003624"
     CDS             complement(5391..5804)
                     /locus_tag="KOU88_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213451.1"
                     /translation="MKVKSKRSFIVGIIVCVLCCASLVIYCILKDKRFLISSFLLIVI
                     AIFNFCNAFSRKGIVEELHDSTDERDLYLTMKTSHILVKIMNYTLFTFTFLFIIAYSA
                     WKNQSLLVIAITLCVIEIFLFVAYLLINIFLEKKE"
     gene            complement(5788..6021)
                     /locus_tag="KOU88_003625"
     CDS             complement(5788..6021)
                     /locus_tag="KOU88_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213452.1"
                     /translation="MKTKVREFRTNMGLTQQQLADLVHVSNRTIISIEKEQYSPSLML
                     AYRMAQVFGTTIEELCCLKENKEMEDKKHESKE"
     gene            6240..6614
                     /locus_tag="KOU88_003626"
     CDS             6240..6614
                     /locus_tag="KOU88_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213453.1"
                     /translation="MKISKLPEAELKVMRYICEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLMSALH
                     GEDDEVDEDKLSELEECFKNLK"
     gene            7226..7918
                     /locus_tag="KOU88_003627"
     CDS             7226..7918
                     /locus_tag="KOU88_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213454.1"
                     /translation="MYNILVVDDDKEIVDSIEIYLKSEGFKIYKAYDGMKALEIITEN
                     DIHLILMDIMMPKLDGIKATVKIREERNIPIILISAKSEDTDKIIGLNIGADDYITKP
                     FNLLELIARVKSNLRRYVTLGNYEDTCKEILKSGALELNTLTKEVKIDGENIKMTPIE
                     YKIIELLLENKGRVFSIDEIYEKVWNEESFNSENTVAVHIRRIREKIEINPKEPRFLK
                     VVWGVGYKIEKF"
     gene            8114..10174
                     /locus_tag="KOU88_003628"
     CDS             8114..10174
                     /locus_tag="KOU88_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK3213455.1"
                     /translation="MEKYRVLKLVSLIIISISFPLTILLVTIGLAEPKYNIQKTSTKS
                     GIFDISDDFYDSNIFDEGTMASLLPKFKLSVGGKLTSKEKGKFQQEGKSIDLSSSDSE
                     YDKIMINEQASEEYLSYLKNIKVYVINTYTGVFYTNTSYASLYDFKQKTKSYCNVEII
                     NKIGKSSYIKTINGEKFELNNLSLELNEVDEGFEAYVSFPEEPTIEDGIVYTNFQIFK
                     QATEKVRLFFVASLSLAIICLLSIILYIKIKGEVLKRNNVFLLIYSKIPMEFNVILVS
                     ISIAILTIYALAVSYHIDVIALVSLSLLIVSNNIFFINVQLSYLENKMCIFKTSIIVR
                     VILWLIKTVREVSNAIKKVSLARKVIVIVIISLALIMVISTRSIGMGLLFSICIFLGF
                     TIYITKRLSYLSYVIEGTERIKKGELDYKIKITGNDNFTSLAENINNIGEGLDRAIEE
                     QVKSERMKSDLITNVSHDLKTPLTSIINYVDLIKKEESIQPEYINDYINVLESKSKRL
                     KLLIEDLFEASRVSSGNIELQISKIDLVQLLRQSIGELEEKLSKNNLYLKLNVPNDKV
                     YIWADGRRMYRVFENLLSNIAKYSLEETRVYIDVYDYGENVKVTMKNISSYELNFDPS
                     EIMERFKRADESRNTEGSGLGLAIARDLVALQGGKFYIEIDGDLFKANLEFQKYEEEI
                     TNME"
     gene            complement(10380..10703)
                     /locus_tag="KOU88_003629"
     CDS             complement(10380..10703)
                     /locus_tag="KOU88_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBK3213456.1"
                     /translation="MNNNYIFFIIIGMYIVTYLPRVLPMLIFSKKEMPDFLKKIMKFI
                     PVAILTSLTAKDVFFNGDSLYLSIANPKIISFMIVLLVAYKFKSIGISIITGVISIYL
                     FGIIL"
     gene            complement(10696..11397)
                     /locus_tag="KOU88_003630"
     CDS             complement(10696..11397)
                     /locus_tag="KOU88_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBK3213457.1"
                     /translation="MERTQQLKESFIASIPIFLGYIPIGIVGGILLQKSGLSPFQIAL
                     MVTLVFGGSSQFIAASMISTGASVTSIVLTTFIVNLRHFLMSSNLNMYIKNKSPKFIL
                     PFCHTITDETFAVNYEKFTAGNWSDRNAIYLNFFCLISSVLANFIGAFLGESISIDSS
                     ISGFILTSMFIALIVSQIKNKIYIVVFISSIIISVILYALFKSNLVIIVASILASLIG
                     FFIEESYCKKEESYE"
     gene            complement(11675..13060)
                     /locus_tag="KOU88_003631"
     CDS             complement(11675..13060)
                     /locus_tag="KOU88_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK3213458.1"
                     /translation="MPINSFENYPMNWKPKRPSKGQILYKALAEQLEQDINNGFLLPG
                     TKLPPQRELADFLDVNVSTISRAFKICEKKGLISGVTGSGTFVSYDTRSNLFLMSSNN
                     KITFIEMGTMNPDFTLEEMNTLFKHIIKEIDFKTIFQYGQRDGAKWQKEAIAKLIYKA
                     GLETTSDSLLPASGGQNAIVAILAGLFQHGDRIGVDPLTYPGIKTAAKMLGIQLIPIK
                     QEDNEISEEGLLYACKNENIKGLYIIPDYQNPTTHIMSQNGRKMIANIASKYNLIVIE
                     DAIHSLLNETHLNPVASYLPNQTIYITSLSKIIAPSLRLAYISTPKQYREALSSALYN
                     INLSQSYFLTEIAYRMITSGEADKLINARRKSARRRNKIINQYLSGYNLLGNEECIFR
                     WLILPDGIMAEKFEIQALKEGVQVYASERFAVGKEKPISAIRIAVCATESTEELKAGL
                     SVLKRLLEEKK"
     gene            complement(13168..>14195)
                     /locus_tag="KOU88_003632"
     CDS             complement(13168..>14195)
                     /locus_tag="KOU88_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBK3213459.1"
                     /translation="IDNYIPYDQGITLDIFMYIWILGIIAISFYYLRTNFKFYNYIEN
                     FKKEILEIDITSILDEQAKELSINKKLQIYKVKGIYSPAIIGLTRCKIIIPEKKYNNK
                     ELRFIFKHELIHYKRKDNLFKLLISTICIIYWFNPILYLLKKYFHELCELSCDEIVID
                     KCTTSEIKEYAYIILDTIKYQKTLKYSSFVSQFLNKKNIILKKRLDSMFNQDKKKINL
                     GLKFLLTFIIIGSIFSINSNFKQNEDVEYTIGKINYNKNGETYGTHIIDSNGNSIEPE
                     LIQTIGRGKKVGYVKKRNLYDCDNQPKTPEEAVLYTRKRNFNIFKKTIPLYDKEGIKI
                     IGRFEIN"
BASE COUNT         5546 a         1575 c         2092 g         4982 t
ORIGIN      
        1 gaaaaaatat tgcatataat attttttata gtcaataaaa atatgaaatt ttttatacac
       61 aatgatgatg aatctaacta gatgaataaa tttaattgta aataagaaag tacttactta
      121 aatggtaggt gcttttgttt tgccaaatta tgctataaca ttgagtgaga tgagtaattt
      181 gtgggggaat tttacaatgt ggatattagt accaataata acaatagtat tacttataat
      241 agctgtttct tctatgcaat atattttagt tatgatagct tttttgttga ttatatattc
      301 ttttatagaa aagaaaatag ttatggctct tgtgtcagtt ctttttttca cttattcaat
      361 ttatctttgt gcaacttgga aagataaatc cttgatagca gataataaag ttgagactgt
      421 taaggcacaa agagaaactg tagaaagaga aaaagaaatg gaaagaagaa gaatacaaga
      481 agaagtagac aaagaaagat atattgaaaa acatggaatg gaaatatcag aaaatgattt
      541 aaaagttaag ctagaggctt tagtacctca agaatataag gggaagaaat atgaattaaa
      601 agtagaaaaa tttaaaagat atagtatgta ttttgattta actgtacaaa atgaaaaatt
      661 tagtaattct gaagaatgta aaaaatttgt aaaagaaatt gctaatgatc ttaaaaaaat
      721 taaaataagc aaggcgtact ttaagtttca ttcaaaagat gacggcggta tatataattc
      781 tgtttatatt gattatttta gaaacataca aaataatgta gataatgttg aaaatttaga
      841 attcaatgag tttgaactta aaaccgaaga agaagagaag cgagaacaag agaaaataga
      901 acaagaaaaa aacagttata ataactacat tcaaaacaga gtggttgacc cactagatag
      961 aataaagaaa ctaaaagagt tgctagattc aggagcaatt acacaggaag aatataataa
     1021 aaagaaaaaa gaattattag aatagataat atagtaagca cttacaagta tgtaggtgct
     1081 tttaaattta caaagtattc cattttaatt ttatagttta gattttatga tataataaaa
     1141 atatagaagt tttgcagtgt gcgatatttg ttacaaagta gggcttaata cttgaaatct
     1201 aagatgttga gggtgcgtga taagtgttat caattgcact attgcccgct cactgcaatt
     1261 ttaagagtat tgtatatatg taggtattgg aaatgctaag tttattttgg ggttttagat
     1321 taactatatg gaatgtaaat ttttattttt gaaaataagg ttggtatgct gctcccagtt
     1381 ttagattaac tatatggaat gtaaattgct tacgaatggt tggaattaca tctattgcta
     1441 acgttttaga ttaactatat ggaatgtaaa tcaatatgat tttgcattag attttagtga
     1501 aggattagcg ttttagatta actatatgga atgtaaattt tctttaaaac agacatcaat
     1561 ttcgttatat ctggttttag attaactata tggaatgtaa atttagaatc aaaagcactt
     1621 aatcctagtt ctttcatagt tttagattaa ctatatggaa tgtaaatagc tttttagctt
     1681 cgtctactac tttataagca aagcgtttta gattaactat atggaatgta aataaaagtt
     1741 gcacgcctat ttgatttttc aatacattat gttttagatt aactatatgg aatgtaaatg
     1801 acaaagcgac tattactatc tcaggtgata aaaatgtttt agattaacta tatggaatgt
     1861 aaatgatgaa caataaaaca atcatctaaa gacgaagaaa gttttagatt aactatatgg
     1921 aatgtaaatg ttcctgttgt gttttttact aatcccattt tatatgtttt agattaacta
     1981 tatggaatgt aaattgctgt gatttcacta ataaaacaat taataattgt gttttagatt
     2041 aactatgtgg attcaaaatt aaataaacaa agaaagcact tacaaatatg taggtgcttt
     2101 tattctgctc aaaattggtc ggttgggtaa aatcattaga aaaaattagt aaaaacctct
     2161 tttctgtaac tcgttacaat attattatta atgtaacgag ttacagaaaa gaggtgaata
     2221 aaatagcaac taaaagtagg gcagagtata tgaaaaattg tcgaaaagat aaaagaggtt
     2281 ttagtgtact tttagacaaa gaaaagttag ataaatttga tgaagtatta gaggaaaaga
     2341 atctaaccaa gaaagaatgg ctagaagaaa aaatcgacga ggaactggaa caaaaggaat
     2401 aaaaaataag ggtcactccc accgaccaaa gtttgagtaa cccctatgat gtatactatc
     2461 gtatatcaat tataatatat gtcattcctt aaaaaaatca attattaagg agtgtaatat
     2521 tatgaaaaat gaattaatga tgtttgaagg aaaagagatt gaagtatttg aatttgaagg
     2581 aagaatttta ttcaactcaa aagatgtagc aaattgttta gacataaaaa atgttaatga
     2641 gaatataata cttatgaatg aaaagcaagt tgtaaagtta agaaattcgg atatcagtaa
     2701 tactgacatc cgaaaactta ataatgctgg agaaaatttt cttactgaaa gtggagtgta
     2761 taaattaatc tttaaatcaa gaaaagaaga agctgagaga ttccaagact ggataagcga
     2821 tgaagtttta ccaagcataa gacaaactgg tgcatacata actaataatg taatcccgaa
     2881 aagttgagag aaaaagcaag tgagattgaa aaattacagt tgcttataac agtacatcta
     2941 tgttaaaaga attgctagat gatgcaggct ttgacaataa atcaaaacta ttaacagcta
     3001 aaacattata taagaaagca gaaattgatt taccaataga gataaacgaa gaagaacatt
     3061 attttgatac aaaacaaata gcatctaaac tgaaaatata ttctaagagt aataaaccag
     3121 ctcagatggc tgtttgtgag attattaaaa agattgattt agaagatggt gaagttaaag
     3181 gtgtttggga aattaatggt tcttggactg gtactgtaaa taaatataca aagagtgtaa
     3241 tagataaggt gagaacttgg atagaggaaa ataatagacc taccaagatt gcaggtgaga
     3301 agaagaatta ttatgtattt tacaaaattg agtaaattta tcagttgtat taaataattt
     3361 agtttagttt tggggggatt aatacaatgt gtgagaattt acttgataat atgtatattg
     3421 aaaagagaaa agaagaatat agaattaaac ttttgaaaat aagagaaaca gatatagata
     3481 tatataataa gttagaaagt atagtatata aactttctga gaaaaaatta gagaaaaata
     3541 ataaatagac atataaagca cttggatatt ctactgtttc aagtgcttgt ttggtataaa
     3601 atggtataat ggagatagag aattatatta accaaaaaat ggagaaaata gagaagatga
     3661 tttagttgac gctttatcag taggagtacc tgcaggtaag acagaatctc tagtacgatt
     3721 agttggagat ggaataagtg atactcaaaa aagtttaata aataaaagag aatttagaaa
     3781 tataactcaa attggtggaa atggaaatga gaaagcattt agtgaagtag aaaacttagt
     3841 taaatagatt agaaggtagc aactagagtt ggttgttacc ttcttttttt atactttctc
     3901 tctctaagta ttttattttt catatcttct aatacatcta atgcagtagt ataaaattgt
     3961 atattatttc tataaggtat agctattgga agaatgccct tgttaactaa aaaaataaga
     4021 agtacaataa ataaaagtgt cataatcatt ctaataaaat aattagtgat atctgataaa
     4081 tcaaatgtta agttaattgt tgtagaaaat acaacagcca taatagatat atacaaagca
     4141 aaaatggggt tactattttt ttgtaactgt cctttaagcc tagattgctc tatttctata
     4201 tcttgaatac tttttatgga atccatttca ctataatact tataaacttt taaataatat
     4261 tttttatact tgtttaaagc ttcttcatta tctttaaggt ctttgtcact taactctgat
     4321 ttaacttccc caaaatccat aaaatccctc ctacaatgtt atataatata ctttaattta
     4381 tagcatattt aagaacttat atcagcaatt tgtcgaacga ttttagctaa aaatagagta
     4441 taatgatagg cttattattt ataagatatt attttttata tagttatata tttctttcta
     4501 attagataat ataatgctgt tgttataatg gctactaata ttattgctat tattgtaata
     4561 tctaatcttc ttgtaaataa gcctattgct atatactcaa gacctgttac atagcgataa
     4621 agtacttcta gtttaacagt ttttttctta tctatatttc catatattga ttctaattta
     4681 ttaaaatatt ttttactaca aaaagcagtt ttaggtttaa ttaaatatat tattgtagtt
     4741 cctattataa ctattattcc aataagtata agattgatat ttccaaaatc catagcagat
     4801 acctcctatt aaatttgctt ttcttaatca aagtatatca gtaacacaag tacaaagagt
     4861 atctaaaata ttacaaatat taacaggata gataaaacta tagtaaaaat tgtaataata
     4921 aagcgaacga aaattatcat actaaaacat aagacatgtt ataattgtat tagatagaag
     4981 attaacatac accaaagcac tccttataat aaagagtgct tatttttttg aaattcatca
     5041 atatataaac tatcaagaac cttattcaac acaccttaaa atcgatttaa atagttcttt
     5101 ttgataacat aatttatatg atataataaa aaaatagaag tgtaccacca atacacttct
     5161 atagctataa ctaagcattc tcttgctggg ggagtgcttt tttcatttct ccaaacaaca
     5221 ttatttactt catcagtaat tatcaaatca atctcattat ctttcaaaat ctctgttgca
     5281 gtacaaatta gattatctaa gtcaaaactt cgagttatct ctagttgttt gttatttact
     5341 tctcttttta gtatataagt tttaaaatac atttatatca ccccttgtat ttactctttt
     5401 ttctctaaaa atatattgat aagtaaatat gcaacaaata aaaaaatctc aatgacacat
     5461 agtgttatag ctataactag aagtgattga tttttccatg cactataagc tatgatgaaa
     5521 agaaatgtaa aagtaaataa tgtataattc ataattttaa ctaagatatg acttgttttc
     5581 attgttaagt acaagtctct ttcatctgta ctatcgtgta attcttcaac aatgcctttt
     5641 cttgaaaaag cattacaaaa attaaagatt gctattacaa ttaaaagaaa tgatgaaatt
     5701 aggaatcttt tatcttttaa aatgcaataa ataactaaac tagcacaaca taacacacaa
     5761 actataatac ccactataaa acttcgttta ctctttactt tcatgttttt tatcctccat
     5821 ttctttattt tcttttaaac aacatagttc ttcaatcgtt gtaccaaaca cttgtgccat
     5881 acgataggca agcataagag aagggctata ttgctctttt tcaatagaaa taattgttct
     5941 gtttgataca tggactaaat cagcgagttg ttgctgtgtt agacccatat ttgttcgaaa
     6001 ttctcgtact tttgttttca ttccataacc tctttctata tgaagctaac ttcatgtgaa
     6061 gttaacttca taatatccta aaatgagtaa aatgtcaatc tcattagata agtattataa
     6121 aacctaaaag aataatatgg taaaaattgg atggaattat ttaccttaat tctcttgttt
     6181 gtaaaacttt attgatatag aatttaacat atacataaat cggcaaaggg gcgcgaatta
     6241 tgaaaattag taaattacca gaagcggaat taaaagttat gagatatatt tgtgaagcta
     6301 acaaggtatt aacttctagg gaattagttg ctgcaatgga agaaaaatat gagtggaatg
     6361 aatcaactac atttacagtt ttgaaaagat tagagcgaag agagttttta agtacagaga
     6421 aaataggcaa acttacacat tataatatac tagtaaaaga gaaaaaatat ctaaggtttg
     6481 aaacaaagga atttttgaag aacatacata aaaattcaat ttcaagttta atgtcagcgt
     6541 tacatggtga agacgacgaa gtggatgaag ataaattaag tgaactcgaa gaatgtttta
     6601 agaatttgaa ataagaaaat gacaaattga tacataataa ataaaatgaa ggtatgaaat
     6661 tataactttt tctaccttca ttttgtttat tattctgaac atgttaagaa aatgaaataa
     6721 gtttgtattt tagttatata aattttaata gaatatgtac agtatatagt agatagaatg
     6781 tataaaaata gaatttaaat aagtagctat tattgcagtg aaatgaatgt ttctaagtat
     6841 atttgggtgg aagaatggtg gaagaaaatt agtgaaatgt aattcttcca ccattcttcc
     6901 acctagaaaa tagaaactgt ttaataagaa ttaatataca ttaattcagc tgaatgcaat
     6961 caaaatactt aaatgaaagt aatctgaaaa caacataatt caaatcaatt tattcaaata
     7021 aacctcaatt tatcttaaat cttaagaaat atttaagaat taggataata ttttcttaag
     7081 atttatattt tattatatag ttataaggga aagttacaaa aatgtaagcc aaagtaatat
     7141 aacaatttag tcattgttga gaaagggagt gaaagatatt gtataatata gataagtatt
     7201 attatacaat agaggaagtg aaaatatgta caatatatta gtagtagacg atgataaaga
     7261 aattgttgat tcgatagaaa tatatcttaa atcagaagga tttaaaatat ataaagcata
     7321 tgatggaatg aaagctttgg aaataataac agagaatgac attcatctaa tactaatgga
     7381 tataatgatg cctaaattag atggaatcaa agcaactgta aaaatacgag aagaaagaaa
     7441 tattccaata attttaattt cagcaaaaag tgaagataca gataaaataa taggattaaa
     7501 tattggagct gatgattata taacaaagcc atttaatcta ttagagctta tagctagggt
     7561 taaatcaaac ttaagacgat atgtaacttt aggtaattat gaagatacat gtaaagaaat
     7621 tctaaaaagt ggagctttgg agttaaatac actaacaaaa gaagttaaaa ttgatggtga
     7681 aaacataaaa atgactccaa ttgagtataa aataattgaa cttcttttag aaaataaagg
     7741 acgagttttc tcaatagatg agatatacga aaaagtatgg aatgaggaaa gttttaattc
     7801 agaaaataca gtagcagtac atatcagacg aataagagaa aagattgaaa taaatccaaa
     7861 agaaccaaga tttttaaagg tggtgtgggg agttggttat aagattgaaa aattttagtg
     7921 gaaaaattat aaaagaaaag agtttaatat ttaattgcat tttgatttta gtcattttta
     7981 catttacaca aatgttagga attttaatat gttttaattt tttctctgag agtttaattt
     8041 actctatggg gattatgctt ttcttaaact ttattttata taaaatactg acaatgtaga
     8101 tgaggtgggc aacttggaga aatatagagt attaaagtta gtttcattaa tcataatatc
     8161 tatctcattt ccattaacta tattgttggt gacaatagga cttgctgagc ctaaatacaa
     8221 tatacaaaaa acttctacaa agagtgggat ttttgatata tctgatgatt tttatgatag
     8281 taatatattt gacgaaggaa caatggcaag tctattaccc aagtttaagc tatctgtagg
     8341 tggtaaatta actagtaaag aaaaaggtaa attccaacaa gaaggtaaaa gtatagattt
     8401 aagtagtagt gattctgagt atgataaaat catgattaat gaacaagctt ctgaagaata
     8461 tttaagttat ctaaaaaata taaaagtgta tgttattaat acatacacag gagtatttta
     8521 tacaaatacg tcatatgcta gtttatatga ttttaaacaa aaaactaaga gctattgtaa
     8581 tgtagagata ataaataaga taggaaagag ctcatatatt aaaacaataa atggagaaaa
     8641 atttgaactg aataatctga gtctggaact aaatgaagta gatgaaggtt ttgaggcata
     8701 tgtatctttt ccagaagagc caactataga agatggaata gtatatacta attttcaaat
     8761 atttaaacaa gctacagaaa aagtaagatt attttttgta gctagtttaa gtttagcaat
     8821 tatatgttta ttatctataa ttttatatat caaaataaaa ggtgaagttt taaaaagaaa
     8881 taatgtattt ttactaatat acagtaagat acctatggaa tttaatgtaa tattagtatc
     8941 tatttcaatt gcaattttaa ctatatatgc tcttgctgta tcttatcata ttgatgtaat
     9001 tgcattagtt tctttatctt tactgatagt atcaaataat atatttttta taaatgtgca
     9061 attgagttat ttagaaaata aaatgtgtat atttaagaca agtattatag taagagtgat
     9121 tttatggtta ataaaaactg taagggaggt cagtaacgct ataaagaaag tatctttagc
     9181 aaggaaagtt attgttatag tgataatatc tttagcttta atcatggtaa ttagcactcg
     9241 aagtataggt atgggattac tgttttctat atgtattttt ttaggattta caatatatat
     9301 aactaaaaga ctttcatatc ttagttacgt aatagaaggt acagaaagaa taaaaaaggg
     9361 agaattagat tataagataa aaattactgg gaatgataat tttacgtctt tagctgaaaa
     9421 tataaataat attggagaag gtcttgatag agctatagaa gagcaagtaa aaagtgaaag
     9481 aatgaagtct gaccttataa caaatgtatc tcatgatttg aaaactccac ttacttctat
     9541 aataaattat gtagatttaa ttaaaaaaga agaatcaata caaccagagt atataaatga
     9601 ttatataaat gtacttgagt caaagtcaaa aagactaaaa ttattgatag aagatttatt
     9661 tgaagcgagt agagtaagta gtggcaatat agaattacaa attagcaaga ttgatttagt
     9721 gcaactatta agacaaagta taggtgaact tgaagaaaaa ttatctaaaa ataatttata
     9781 tttaaaatta aatgttccaa atgataaggt gtatatatgg gcagatggaa gaagaatgta
     9841 tagagtattt gaaaatcttt tatctaatat agcaaaatat tccttagaag aaactagagt
     9901 ctatattgat gtatatgact atggtgaaaa tgtaaaggta actatgaaaa atatatcttc
     9961 ttatgaatta aattttgacc caagtgagat tatggaaaga tttaaaagag ctgatgaatc
    10021 aaggaatact gaaggaagtg gattagggct tgctattgca agagatttag tagctttaca
    10081 aggtggaaaa ttttatatag aaatagatgg agatttattt aaagcaaatt tagagtttca
    10141 aaaatatgaa gaagaaataa caaatatgga atgagatagt atttaagtat atatattttt
    10201 tttactgtcg aaagctttta ttataatata ttagaatatt tacagtagag aatgaagagt
    10261 aaaaacagag taactttaag tcactctgtt ttttatttaa aatcaataat ataacaactt
    10321 aaattaaaat tgtacacata gttttaaaat aacttataca ataaaacatt atccaaatat
    10381 cacaagataa ttccaaataa atatatagat atcactcctg taataataga aataccaata
    10441 gatttaaact tatatgcaac aagaagtaca atcataaaag atataatttt agggttagct
    10501 atagataaat atagactatc tccattaaaa aatacatctt tagcagttaa ggaagtaagt
    10561 attgctacag gtataaattt catgattttt ttcaaaaaat caggcatctc tttttttgaa
    10621 aaaattaaca taggaagcac tcttggtaga tatgtaacaa tgtacattcc aattataata
    10681 aaaaatatat aattattatt cataagattc ctccttttta cagtaagatt cttctataaa
    10741 gaaaccaatt aaagatgcta aaattgatgc aactattatt actaaattgc ttttgaataa
    10801 tgcatataaa ataacagaaa taatgattga tgatataaat actacaatat aaatcttatt
    10861 ttttatttga gaaactatta aagctataaa catagaagtc aatatgaagc cagaaataga
    10921 actgtctata gatatacttt ctcctaaaaa tgctccaata aaattagcta aaactgatga
    10981 aattaagcag aagaaattaa gataaatagc atttctatca gaccaatttc cagcagtaaa
    11041 tttttcataa ttaactgcaa aagtttcatc tgttatagta tgacaaaatg gcaatataaa
    11101 ttttggactt ttatttttta tgtacatgtt caaattagaa ctcattagaa aatgtcttaa
    11161 gttaactata aatgtagtca aaacaataga tgttacactt gcaccagtag aaatcattga
    11221 agctgcaatg aattgagaac ttcctccaaa tactaaagtt accattagtg ctatttgaaa
    11281 aggtgaaaga ccagattttt gtaatagtat tcctcctact atacctatag gtatataacc
    11341 taagaatata ggaattgaag caataaagct ttcttttaat tgttgagttc tttccacaat
    11401 aaatcactcc ttttgtatta aatgtattaa agtattagta aaacagaaaa atagattaat
    11461 tgtataattg caattataat taaaaataaa tttggattaa tgtataaaat actatacaac
    11521 aaataaataa tcttaaacgg ttattaaatt ttatctattt gttattatga tgtaataata
    11581 catattaatc tctataagtt aattactatc tggtgtaatt ttattttaac aacaaaaaaa
    11641 aatacacaca attaaaatat tgtgtgcaat acaattattt tttctcttct aatagtcttt
    11701 ttaatacgct caaaccagct ttaagttctt ctgtactttc tgtagcacat acagctattc
    11761 ttattgcaga aattggtttt tcttttccaa cagcaaaacg ttcagaagca tagacctgta
    11821 caccttcttt aagtgcttgt atctcaaatt tttctgccat tattccatca ggtagaatca
    11881 accatctaaa tatacattct tcatttccca aaagattata tccagataaa tattgattaa
    11941 taatcttgtt tcttcttctt gcagatttac ggcgtgcatt aattaattta tcggcttcac
    12001 ctgatgtaat catgcgataa gcaatttctg ttaaaaaata agattgagat agattaatgt
    12061 tgtataatgc gcttgataat gcctctcgat actgtttagg tgtagagata tatgctagcc
    12121 gtaaactagg tgcaataatt tttgataaac tcgtaatata aattgtttga ttgggcagat
    12181 aggaagccac tggatttaaa tgtgtttcat taagtaaact atgaatagca tcctcaataa
    12241 caattaaatt gtatttagat gcaatatttg caatcatttt tcgtccattt tgtgacatta
    12301 tatgtgtagt tggattttga taatctggta ttatgtatag acctttaata ttttcatttt
    12361 tacaagcata taatagtcct tcttcactaa tctcattatc ttcttgttta attggaatta
    12421 gttgaatccc aagcatttta gctgctgtct ttattccagg ataagttaat gggtctacac
    12481 ctattctatc tccatgttga aacaaaccag ctaaaatggc aacaattgca ttttgtccac
    12541 cacttgcagg aagtaagcta tctgatgtag tttcaagccc agctttataa attaatttgg
    12601 caatagcttc tttttgccat ttagcaccat ctctttgtcc atattggaat atggttttaa
    12661 aatctatttc cttaattatg tgtttaaaca aagtattcat ttcttctagc gtgaaatctg
    12721 gattcattgt gcccatttca ataaatgtaa ttttattatt actggacatc aagaatagat
    12781 ttgaacgtgt atcataagat acaaaagttc cacttcctgt aactccactt attagacctt
    12841 ttttttcaca aattttaaaa gctctagaga tagtactcac attaacatct aagaaatctg
    12901 ccaattcacg ttggggtggt aatttagtac ctggtaataa aaatccattg ttgatatctt
    12961 gttctagttg ttctgcaaga gccttatata atatttgacc ttttgaaggt ctctttggtt
    13021 tccagttcat aggataattt tcaaaagaat taattggcat aagttttcac ctcacattat
    13081 taatttgatt ttttctttat ctaaaacaat aaattctaaa gatacaaata aaaactgata
    13141 ggaaataatt ctatcagttt ttgtctttta attgatttca aatcttccta taatttttat
    13201 accttcttta tcataaagag ggattgtttt tttaaatata ttaaaatttc tttttcttgt
    13261 atataaaaca gcttcttctg gtgtctttgg ttgattatca caatcgtaca aatttctttt
    13321 ttttacgtag ccgacttttt tacctctacc tattgtttgt ataagttctg gttcaatgga
    13381 atttccattt gagtctatta tatgtgtacc ataggtttct ccatttttat tataattaat
    13441 cttaccaata gtatattcta catcttcatt ttgtttaaaa ttggagttga tagaaaatat
    13501 tgaccctatt attataaagg ttaataaaaa cttaagacct aaattaattt tctttttatc
    13561 ttgattaaac atagaatcta acctcttttt taaaataata ttttttttat ttagaaactg
    13621 agatacgaat gatgaatact tcaaagtttt ttgatacttt attgtatcta atattatata
    13681 tgcatactct ttaatttcac tcgtggtaca cttgtcaatc acaatttcat cacaagataa
    13741 ttcacataat tcatgaaaat atttttttaa taagtataaa attggattga accaatatat
    13801 gatacaaatt gtactaatta gaagcttaaa taagttatct tttcttttat aatgaattaa
    13861 ttcatgttta aagatgaatc ttaactcttt attattgtac tttttttctg gaattattat
    13921 tttacagcgt gttaaaccta taatggcagg agaataaata cctttaacct tatatatttg
    13981 aagtttttta tttatactta gttcttttgc ttgttcatct aagatactag taatatctat
    14041 ttctaaaatt tcttttttaa aattttctat gtaattataa aatttaaaat ttgttcttaa
    14101 atagtaaaaa gagattgcta taattcctaa tatccagatg tacataaata tatctaaagt
    14161 aatgccctgg tcatatggta tataattatc gatat
//
LOCUS       DAFAZV010000075        14053 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFAZV010000075 DAFAZV010000000
VERSION     DAFAZV010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14053
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.077"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            96..1457
                     /locus_tag="KOU88_003633"
     CDS             96..1457
                     /locus_tag="KOU88_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK3213460.1"
                     /translation="MELFKAESKKYKKEFLKLLEQWVSIPSFYDRKTVSKDMPFGKGV
                     YDALNWFENLGRENNFKVKNIDNHAVQIEYGNGKEYVDIFGHCDVVNPGEGWDSEPFK
                     LNIIGDKLVARGVSDNKGPMIVNFLALKMIKDLDINLKRKVRLIAGGNEESGFKCIKH
                     YYSKEPYGVCGFTPDAKFPVLNGEKGGAIIKLISNIDDKSLYISGGIEFNTIPDKVYI
                     KNVEKLGKDNICFDINNISINYDNGNYIVYGKGGHSSKPEKSINPILATIKLLSENID
                     EKWTKDLYKLINQDNINGNLFGLNIEGKCGILSMVPTIINIVDGKLEVVLSVRYPEIL
                     TIEDIIKKFNLYMEQNNINKFELIGENLKQANYIDRNSKLVRSLHDIYIKYSGDLKND
                     VRVTSAGSYASEMNNSVIFGCEFPDGSFGNVHSANEFASLDRFITAIGIYAEAIITLC
                     NKI"
     gene            1545..3434
                     /locus_tag="KOU88_003634"
     CDS             1545..3434
                     /locus_tag="KOU88_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HBK3213461.1"
                     /translation="MITKKHAIIVKSLSNKDGYMTSNELAIKLDVSTKTIKRYIADLN
                     SVLSKYDLVIASSRGIGYKLSGSKNNIARAVKEANKYIDGFLDDSEESRMSNIICMLI
                     NRNYMSIEAMAEELNLSIAAINKLSSKLKRKLEKYDLVIKSKPYYGSYIHGEEINIRQ
                     LITDYAIKLDEKSKVKVFLDDISENDIHCIESILEKHLREKDTIISDKDFNLLLSKII
                     VSVFRSKRGHSNNINLMDTSYRFHNYYFIENLMKEISDKIGFKLIEDEVIYISNYSGV
                     IAYKGTQGRKNTSEIEERISTVISSALQDIFLISGSDYTKDDEFMVAISDHIKRFLNR
                     ARANVKSNNPLLHQIKEKFPIAFNLAVFLSNKLETEFNLKLDEDELGYIAIHFAASNE
                     RMKKNTSKKICIVCHYGIGTGQLISEKLKQNISDLSVVGVYPVRYLDMAISQDVDLIV
                     STVELKGYEKPVLYIENIFDDSLIENVNKAFYEKEERRKIISNMFDEKAFFSIKASTK
                     EEVIISLSNKLKERDFIEESSIKSIIDRENISSTEIGNLVAIPHTIVKGDKKSIIGVG
                     ILENPIIWDKQEVQLVFMVFFNTKEKHNFSIFKYLYNFIKDEGGVRGIIKICDFNKLM
                     ALIGN"
     gene            3449..3904
                     /locus_tag="KOU88_003635"
     CDS             3449..3904
                     /locus_tag="KOU88_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3213462.1"
                     /translation="MGTNIFNKEYVFLNVDAKSKVEVLKFISKKAKDLNLAEDESLVY
                     EGLMAREEQFTTNLGESIAIPHTKNDAIENPAVVVLKFNEDVVWNEGEDKVKLAISLL
                     MPGKSKENIHLKLLSSLSRKLINKEFKDSLLKSDNVEEISNLINEALGL"
     gene            3963..4280
                     /locus_tag="KOU88_003636"
     CDS             3963..4280
                     /locus_tag="KOU88_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBK3213463.1"
                     /translation="MNKKLVALCACPMGLAHTFMAAEAIEQAAKALGYEAKVETQGAD
                     GVQNELTRDDILGATMIIHAVAITPEGMERFDGCEVYEVELQEAIKNAEGVIKEIEED
                     LGI"
     gene            4305..5567
                     /locus_tag="KOU88_003637"
     CDS             4305..5567
                     /locus_tag="KOU88_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBK3213464.1"
                     /translation="MAIKKKVINSSGASTTGGNNVGKSTPSSPTQSKGNGKWKEISKH
                     IMTGISYMIPVLVMGGLIGALSQLIPYAILGLDPSVGIVDAMNSGEFTGFKLSLLNIA
                     QLMSNFGFTLFGFAIPLFAAFCANSIGGKTALIAGFIGGYIANKPVGVPQFVDGQWTE
                     VVPVASGFLGAILIAFIIGYFVKWLNKSIKVSHNWLAFKTTFLIPLIASLACMVLMIF
                     IITPFGGLINESMKNFLTAAGAAGEYVYATALAAATAFDLGGPINKAAGFVALGLTTE
                     NVLPITARTIAIVVPPIGLGLTTLLDKRLVGRRVYDRQFYQAGKTSIFLSFMGISEGA
                     IPFALERPGFVIPLNIVGSVIGAITGIILGAIQWFPESAIWAWPLVDNLFGYIIGIAV
                     GAIFIAVGNIFYRNKLIKDGKLVVDYID"
     gene            5672..6736
                     /locus_tag="KOU88_003638"
     CDS             5672..6736
                     /locus_tag="KOU88_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK3213465.1"
                     /translation="MDKIEKVREYFREYDIDGFLINSPTNKFYVGNLFSSSGYVFITK
                     ESQYIIVDFRYFEEIKRKSSLFNVVLMDKTRTHFDIINDICREQNIKEIGFEGNEVSF
                     DLYRSMSNKLSATLKSVDLSTLRETKNEDEIKYIKKACEIVDATFYHIVDFIKVGMTE
                     KQVENEIVRIIKDLGGQKESFDTIVASGLRGALPHGKASEKVIEYGDFVTFDFGAKYN
                     NYCSDITRTICMGTINKELEEIYNIVRKANEECIRVLRPGMTTGEIDKVARNIIGSYG
                     YANNFGHNLGHGVGIMVHEYPALAPESNEVLKEGMIVTIEPGIYVPSLGGVRIEDDVL
                     ITQDGCMRLTTSTKDLIVVS"
     gene            6790..7968
                     /locus_tag="KOU88_003639"
     CDS             6790..7968
                     /locus_tag="KOU88_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PatB family C-S lyase"
                     /protein_id="HBK3213466.1"
                     /translation="MYNFDDKPDRVSEKCRKWDLNIIRDKFGDIREDFIPMWIADMDF
                     KIPTEIENKFIEAVRRGVFGYTYCYDEFYDSVIGWQKNMHEVNVEKEWITLTYGTVST
                     LHYVVQAFCKKGDSIILNTPVYDPFESSAKKQGVNVICNTLDVVNDRYYINFDKLEVQ
                     IKENKPKLMMFCTPHNPSGRIWTIEEMTRVATICKENNVILVADEVHAEHIHYGKFNS
                     ILKIGKELLENVILLTSPNKGFNLGGLKTSYSIVINKDIRDKFRNKLKQNSITSPNVF
                     GIIGLITAYNECHEWLSGVNEYIKSNYELLETWVNKYNKIKLMKMESSYLAWMDISGL
                     GISASEFTDKLAIDTGVLLEDGSHFVKDGEKYVRINLGTQKENVIEALNRMDLFLKSL
                     "
     gene            complement(8159..9217)
                     /locus_tag="KOU88_003640"
     CDS             complement(8159..9217)
                     /locus_tag="KOU88_003640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBK3213467.1"
                     /translation="MNKKKITFIFVILILALILFSFFRSSSQNTKYSKTSYYLGTVNE
                     VTVFNVKESKSDKILNECDSILRYIDNKMSTHIPGSDVSKINDNAGKKFVRVSDDTFF
                     VVKEAIQYSKLSDGYFDITIGPLSNLWAIGTDKAKVPSDSEIQKLLPLIDYKNIILDE
                     KNKSIKLTKENMKIDLGAIAKGYAADKIVAYLKSEDVKKGLVNLGGNIFTLENGKNDK
                     PFKIGIQDPTSKNGESIGNIETTNKSVVTSGIYERFIEKNGKIYHHMLNPFTGYPFEN
                     NLSSVTIISDKSINCDALSTSTFGLGLEKGMDLINKIDNVDAIFITKDKKVYLTKGIK
                     DNFKLTDKSFSIEKLNKQ"
     gene            9284..9655
                     /locus_tag="KOU88_003641"
     CDS             9284..9655
                     /locus_tag="KOU88_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBK3213468.1"
                     /translation="MKKKDILLILGILVVITACYGIINVINSKNAGNIEIYVDNKLYK
                     TVSINAKEEFKIENRGGYNIVKIHDKGVEIVDASCPDKVCVHTGFINKPSQSIVCIPN
                     RVSIKINTNEKNDNQEDIISK"
     gene            9692..10366
                     /locus_tag="KOU88_003642"
     CDS             9692..10366
                     /locus_tag="KOU88_003642"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBK3213469.1"
                     /translation="MVNLGNDWDELLKEEFEKDYYLNLRKFLIEEYKTRQIFPNMHNI
                     YEALKHTSYKDTKVLILGQDPYHGDNQAHGLAFSVQPQVKTPPSLLNMYKELKDDLGC
                     FIPNNGYLMPWADQGVLLLNTALTVRAHEANSHKNKGWEIFTDRVISILSEREDPVIF
                     VLWGSNARKKVELIDTSKHYILEAPHPSPLSASKGFFGCKHFSKINEILKKLGKEPIN
                     WQIENI"
     gene            10615..11454
                     /locus_tag="KOU88_003643"
     CDS             10615..11454
                     /locus_tag="KOU88_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HBK3213470.1"
                     /translation="MNFKKLSNAKVSVMAVVLSVGILSGYSALNKQVTLVVRGEERTI
                     STFSSNVGDLLESQNISYDANDIVTLDENTKLSNGDKIEVIDVKEKTVVETKDIPFEV
                     TVVEDGSLLKGDSKVKEEGKSGKSELIYKETYHNGKKVEKEFVKKVVKAEPVNKVVSK
                     GTKVEMQVASSRGESSRRMASSSSSSSSSNNGKNMRVVATAYTGHSITATGTKPKWGT
                     IAVDPKVIPYGTKVYIPQFDMVFTAEDCGGAIKGNKIDIYMNDSKTVYNWGRKTIDIR
                     ILK"
     gene            11698..11794
                     /locus_tag="KOU88_003644"
     tRNA            11698..11794
                     /locus_tag="KOU88_003644"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11732..11734,aa:Sec,seq:tca)
     gene            11945..12652
                     /locus_tag="KOU88_003645"
     CDS             11945..12652
                     /locus_tag="KOU88_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003416532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HBK3213471.1"
                     /translation="MENNFTTRTSFLVGDDGIKKLNNSNIIVFGVGGVGSFTVEALAR
                     AGVGNITIVDFDDVDITNINRQIPALHSTVGRYKVDVMEERILDINPNINIKKIRSLY
                     NKDTSDEILTERYDYVVDAIDMVSSKIHLIETCEKKGLKIISSMGMGNKLDPTKIVVT
                     DIHKTSTCPLAKVMRKELRDRGIKKLKVVYSTEQPIELKKKVMNGRKVTPGSVSFVPS
                     VGGLIIASVIVNELLGQ"
     gene            complement(12794..13630)
                     /locus_tag="KOU88_003646"
     CDS             complement(12794..13630)
                     /locus_tag="KOU88_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3213472.1"
                     /translation="MRNKIFLSILIIISLLIGCDKKSLLSIHMIDVGQGDSILVQTPT
                     NKNILIDGGDEDSENIIISYLRQKRIKTIDIIIATHPDSDHIGSLDNIIKKFNVNSIY
                     MPEQSTDSEAYQNLINSCTDKNLSIQHLYKNDVLNIDNNINIYVLSPSYIQEESNLNS
                     IVFKLTFNDNSFLFMGDAEEENEKEILHSFKLNNINFIKIGHHGSNSSSSLEFIKKIS
                     PDIAAISCGYKNQYGHPHREVINNLKQNHVSIYRTDRIGDIVFYSDGEIIFTKYNYEI
                     DT"
     gene            13818..>14053
                     /locus_tag="KOU88_003647"
     CDS             13818..>14053
                     /locus_tag="KOU88_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213473.1"
                     /translation="MFFKDIELNSKKELDPYFDLVDYEACEYCFSTLYMWQHVYKTGY
                     YIGEDFAVLVGEYEGDSFSILPLAKKDKLPEVVD"
BASE COUNT         5553 a         1440 c         2401 g         4659 t
ORIGIN      
        1 aagttttgtc ccttgaaatg acataaagta taaggagtta ttaaataaga taaactatga
       61 tatataatat aaagttctaa attggagtga taattatgga gttgtttaag gcagaaagca
      121 aaaaatataa aaaagaattt ttaaaattat tggagcaatg ggttagtata ccttcatttt
      181 atgatagaaa aactgtatct aaagacatgc cttttggaaa aggagtatat gatgcattaa
      241 actggtttga aaatctaggt agagaaaaca atttcaaagt aaaaaatata gataatcatg
      301 ctgttcaaat tgaatatgga aatggtaaag agtatgtaga tatatttgga cattgtgatg
      361 ttgtaaatcc aggtgaagga tgggatagtg aaccatttaa actaaatatt ataggtgata
      421 aattagttgc tagaggtgta tctgataata aagggcctat gatagtgaat tttttagcac
      481 taaaaatgat aaaggattta gatattaatt taaaaagaaa ggttagatta atagctgggg
      541 gaaatgaaga gagtggattt aaatgtataa agcattatta tagcaaagag ccatatggtg
      601 tatgtggatt tactccagat gctaaatttc ctgtattaaa tggagaaaaa ggtggagcaa
      661 taataaagtt aatttcaaat atagacgata aatctttata tataagtggt ggaatagagt
      721 ttaatacaat accagataaa gtttatataa agaatgtaga aaaattgggt aaagataata
      781 tatgttttga tattaacaat atatcgataa attatgataa tggcaattat attgtgtatg
      841 gaaaaggtgg tcattcatct aaacccgaaa aatcaataaa tcctatatta gctacaatta
      901 aacttttgtc agaaaatatt gatgaaaaat ggacaaaaga tttatataag ttgataaatc
      961 aagataatat aaatggaaac ttatttggtt taaatattga ggggaaatgt ggaattttat
     1021 caatggtgcc aacaataata aatatagtag atggaaaatt agaagtagtt ttaagcgtta
     1081 gatatccaga aatattaacc attgaagata taataaaaaa atttaatttg tatatggagc
     1141 aaaataatat taataaattt gagcttattg gggaaaattt aaagcaagca aattatatag
     1201 atagaaattc aaaacttgta agaagtttgc atgatatata tataaagtat tctggagatt
     1261 taaaaaatga tgttagagta actagtgcag gaagttatgc ttctgaaatg aataattcag
     1321 taatatttgg ttgtgaattt cctgatggta gctttggcaa tgtccatagt gcgaatgaat
     1381 ttgctagctt agatagattt ataactgcaa taggtatata tgcagaggca ataattacat
     1441 tatgtaataa aatataaata caaaatgtcc cttatataga catattatat atacaattaa
     1501 aattttactt gatatataat tgaaatcaaa gagaaggtga tacaatgata actaagaaac
     1561 atgcaataat agtaaagagt ttaagcaata aagatggata tatgacatca aacgaattag
     1621 ctatcaaatt ggatgtgtct actaaaacta ttaaaagata tatagcagat ttaaatagtg
     1681 ttttaagcaa atatgatttg gtaatagctt cttctagagg tataggatac aagttaagcg
     1741 gttctaaaaa caatatagcc agagctgtta aagaagcaaa taaatatatt gatggttttt
     1801 tagatgactc tgaagagtca agaatgtcaa atataatatg tatgcttatt aatagaaatt
     1861 atatgagtat agaagcaatg gcagaagaat taaatctaag tatagccgct ataaataaat
     1921 tgtctagtaa gcttaaaaga aaacttgaaa agtatgactt agttataaaa tctaaacctt
     1981 actatggaag ctatatacat ggtgaagaaa ttaatataag gcaattaatt actgactatg
     2041 caataaaatt agatgaaaaa agtaaagtga aggtgttttt agatgacatt agtgaaaacg
     2101 atatacactg tatagaaagt attttagaaa agcacttaag agaaaaagat acaataattt
     2161 cagataaaga ttttaatctt ttgctttcaa aaataatcgt ttctgtattt aggagtaaga
     2221 gaggtcatag taacaatata aacttaatgg atacaagtta tagatttcat aactactact
     2281 ttatagaaaa tctaatgaaa gaaatatctg ataaaattgg atttaaactt attgaagatg
     2341 aagtaattta tatttcaaat tattctggtg taatagccta taaaggtaca caaggaagaa
     2401 aaaacacaag tgaaattgag gaacgaataa gtactgttat aagtagtgca cttcaagata
     2461 tattccttat ttcaggtagt gattatacaa aagatgatga gtttatggtt gcaatctctg
     2521 accatataaa gagattttta aatagagcta gagctaatgt aaaatcaaat aatcctttac
     2581 ttcatcaaat aaaagagaag tttcctatag cttttaattt agccgtgttt ttatcaaata
     2641 aactagaaac tgagtttaat ttaaaacttg atgaagatga gcttggatat atagctatcc
     2701 actttgctgc ttcaaatgaa agaatgaaaa aaaatactag taagaaaatt tgtatagttt
     2761 gtcattatgg gataggaaca ggacaactta tttctgaaaa gctaaaacag aatataagtg
     2821 atttaagtgt tgtgggtgtt tatccagtta gatatctcga tatggctata agtcaagatg
     2881 ttgatttgat agtatctaca gttgaattaa aaggatatga aaaacctgtc ttatatatag
     2941 aaaatatatt tgatgatagc ttaattgaaa acgtaaacaa agccttttat gaaaaggaag
     3001 aaagaagaaa gataataagt aacatgtttg atgaaaaagc ttttttcagt ataaaggcta
     3061 gtactaaaga agaggtcata atttcacttt caaataaact aaaagaaaga gattttatag
     3121 aggaaagttc tataaaaagt ataatagata gagaaaatat ttcatcaact gaaataggaa
     3181 atctagtagc aataccccac acaatagtga agggagataa aaaatctata ataggagttg
     3241 gaatacttga aaatccaata atttgggata agcaagaggt tcagctagta tttatggtat
     3301 tttttaatac taaagaaaaa cataatttct cgatatttaa atacctttat aattttataa
     3361 aagatgaagg aggagtaaga ggaattatta aaatatgtga ctttaataaa ttaatggcac
     3421 ttataggtaa ttaaggagga aattaataat gggaacaaac atatttaaca aagaatatgt
     3481 atttttaaat gttgatgcta agtcaaaggt tgaagtttta aaatttatat caaaaaaagc
     3541 taaagactta aacttggcag aagatgagag cttagtatat gaaggtttaa tggctagaga
     3601 agaacaattt actacaaatt taggagaatc tatagcaata cctcacacta aaaatgatgc
     3661 aattgaaaat ccagcagtag tagtattgaa gtttaatgaa gatgttgttt ggaatgaagg
     3721 tgaggataag gttaaattag caataagctt acttatgcca ggaaaaagta aagagaatat
     3781 tcatcttaaa ttattatcat ctctttcaag aaaattaata aataaagaat ttaaagattc
     3841 tcttttaaaa agtgataatg ttgaagaaat atctaactta ataaatgaag ctttaggttt
     3901 ataattaaac actaaggtta taaaataaaa aaataattaa ctaaaaatag gaggaatttg
     3961 aaatgaataa aaaattagta gcattatgtg cttgtccaat gggactagct cacactttca
     4021 tggcagcaga agcaatagag caagcagcaa aggcattagg ttatgaagca aaagttgaaa
     4081 ctcaaggtgc tgatggtgta caaaatgagt taacaagaga tgatatatta ggagcaacta
     4141 tgataataca tgcagtagca ataacaccag aaggtatgga aagatttgat ggttgtgaag
     4201 tttatgaagt tgaattacaa gaagctataa aaaatgcaga aggtgttata aaagaaatag
     4261 aagaagattt aggaatataa taaatttatt gtggaggaaa tagaatggca attaagaaaa
     4321 aagttataaa cagttcaggt gcttctacaa caggaggaaa taatgtagga aaatctactc
     4381 catctagtcc aactcaatca aagggaaatg gaaaatggaa agaaataagt aaacatataa
     4441 tgacaggtat atcatatatg ataccagttt tagtaatggg tggacttata ggggccttat
     4501 ctcaattaat accatatgct atattaggac ttgacccatc tgtaggtata gttgatgcta
     4561 tgaactcagg agaatttaca gggttcaagc ttagtctttt aaatatagca caattaatgt
     4621 caaatttcgg atttactttg tttggatttg cgataccact gtttgcagca ttttgtgcaa
     4681 actctatagg tggaaaaaca gctttaattg caggatttat aggtggatat atagctaata
     4741 aacctgtagg tgtaccacaa ttcgttgatg gacaatggac tgaagttgtt ccagttgcat
     4801 caggattttt aggtgcaata ctaatagcat tcataatagg atattttgta aaatggttaa
     4861 ataaatctat aaaagtttct cataactggt tagcttttaa aacaacattt ttaataccat
     4921 taatagcgtc attagcttgt atggtattga tgatatttat aataactcca tttggtggat
     4981 taattaatga aagtatgaaa aacttcttaa cagcagcagg agcagctgga gaatatgtat
     5041 atgcaacagc tttggcagca gctacagcat tcgacttagg aggaccaata aataaagcag
     5101 caggattcgt tgcacttggt ttaactacag agaatgtact tccaataaca gcaagaacaa
     5161 tagctatagt tgttcctcca attggactag gattaacaac attattagat aaaagattag
     5221 taggaagaag agtatatgat agacaattct atcaagcagg aaaaacttct atattcttat
     5281 catttatggg tatatctgaa ggagcaatac catttgcact tgagagacca ggttttgtta
     5341 tacctttaaa catagttgga agtgtaatag gagctattac aggtataatt ctaggagcaa
     5401 ttcaatggtt cccagagtca gctatatggg catggcctct agtagataac ttatttggat
     5461 atataatagg tatagcagtt ggtgctatat tcatagcagt aggaaatata ttctatagaa
     5521 ataaattaat aaaagatggt aaacttgttg tagattatat cgactagtat ttaattttta
     5581 ctatctataa ataactttgg ctggtaatat ggttttaatc aatattacca gccttaccta
     5641 tatgattaat taaaggcggt ggagataaga tatggataag atagaaaaag taagagagta
     5701 ttttagagaa tatgatatag atggatttct tataaatagt cctacaaaca agttttatgt
     5761 tggaaattta tttagctctt caggttatgt ttttataacg aaagaatcac aatatataat
     5821 agtagatttt agatattttg aagaaattaa aagaaaatct agtttgttta atgtagtatt
     5881 aatggacaaa actagaactc attttgatat aattaatgat atttgtagag agcagaatat
     5941 aaaggaaatt ggatttgagg gaaatgaagt atcttttgat ttatatagaa gtatgagtaa
     6001 taagttaagt gcaaccttaa aatcagttga tttatctaca ttaagggaaa caaaaaatga
     6061 agacgaaata aaatatataa aaaaagcttg tgaaatagtt gatgctacat tttatcatat
     6121 agtagacttt ataaaggttg gtatgactga aaagcaagtt gaaaatgaaa ttgttagaat
     6181 tataaaagat ttaggtggtc aaaaagaatc ttttgataca atagttgcat ctgggcttag
     6241 aggagcatta cctcatggaa aagcaagtga aaaagttata gagtatggag attttgttac
     6301 ttttgacttt ggtgctaagt ataataatta ttgttcagat attaccagaa ccatttgtat
     6361 gggtactata aataaagagt tagaagaaat atataatata gtaagaaaag ctaatgaaga
     6421 gtgtataagg gttttaaggc cgggaatgac tactggagag atagataaag ttgcaagaaa
     6481 cataattggt tcatatggat atgccaataa ttttggtcat aatctgggtc atggtgtagg
     6541 aattatggtt catgaatatc ctgcattagc tcctgaatca aatgaagtat taaaagaagg
     6601 aatgattgta actatagagc ctggtatata tgttccaagt cttggaggcg taagaataga
     6661 agatgatgta cttataacac aagatggatg tatgagattg actacatcta ctaaggattt
     6721 aatagttgta agctaaaaat aaattagata aatattttat aacaataaga aaagaagagg
     6781 taaatttaaa tgtataattt tgatgataaa ccagatagag taagtgaaaa gtgtagaaaa
     6841 tgggatttaa atattataag agataaattt ggagatatta gagaagattt tataccaatg
     6901 tggattgctg atatggattt taaaatacca acagaaatag aaaacaaatt tattgaagct
     6961 gtaagaagag gtgtatttgg atatacatac tgttatgatg aattttatga ttcagttatt
     7021 ggttggcaaa aaaatatgca tgaggtaaat gtagaaaaag aatggattac attaacttat
     7081 ggaactgtat caacacttca ttatgtagta caagcttttt gtaagaaagg tgatagtata
     7141 atattaaata caccagttta tgaccccttt gaatcatcag caaaaaaaca aggtgtaaat
     7201 gtaatttgta atacattaga tgttgtaaat gatagatatt atataaattt tgataaatta
     7261 gaagttcaaa ttaaagaaaa taagcctaaa ttaatgatgt tttgtacacc acataatcca
     7321 tctggaagga tatggacaat tgaagaaatg acaagagtag caactatatg taaagaaaat
     7381 aatgttattt tggttgcaga tgaagtacat gcagagcata ttcattatgg taaatttaat
     7441 tcaatactta agattggaaa agagctttta gaaaatgtta ttctactgac atcaccaaat
     7501 aaaggattta atcttggtgg attaaagact tcttattcaa tagttataaa taaggatata
     7561 agggacaaat ttagaaataa attaaagcaa aattctataa cttctccaaa tgtgtttgga
     7621 ataataggat tgataaccgc ttataatgaa tgtcatgagt ggttaagtgg tgtaaatgaa
     7681 tatataaaat caaattatga acttttagaa acttgggtaa ataaatataa taagataaaa
     7741 ttgatgaaaa tggaatcatc ttacttagct tggatggata taagtggatt aggtattagt
     7801 gcaagtgagt ttacagataa attggctata gatacaggag tattattaga agatgggagt
     7861 cattttgtaa aagatggtga gaagtatgtt agaataaatt taggaactca aaaggaaaat
     7921 gtaattgaag ctttaaatag aatggattta tttttaaagt ctttataaaa atttggttga
     7981 attagtattt tatataaatt taaactatta atatggtata tacataagta gaatttgttt
     8041 tagattactt aagtatatac catattttat ataaaaatta aatttgcatt agtcatgtga
     8101 taactattta aattcatatg tattttgtat gtataataga tataattatt atttaaactt
     8161 attgtttatt taatttttca atagaaaaag atttatctgt aagtttaaaa ttatctttta
     8221 tacccttagt taagtatact ttcttatcct tagttatgaa tatagcatct acattatcaa
     8281 ttttattaat taaatccata cctttttcaa gaccaagtcc aaatgtagaa gtggataagg
     8341 catcacaatt aatagattta tcagagatta ttgtaacact acttaaattg ttttcaaaag
     8401 gataccctgt aaatggattt aacatatgat gatatatttt tccgtttttt tcgataaatc
     8461 tttcataaat tccagaagta acaacagact tatttgtagt ttctatgttt cctatggatt
     8521 caccattttt actagttggg tcttggatac ctattttaaa aggtttatca tttttaccat
     8581 tttctaaagt aaatatattt cctcctaagt ttactaaacc tttttttacg tcctctgatt
     8641 ttaaataggc tacaatttta tcagcagcat atcctttagc tatggcacct aaatcaattt
     8701 tcatattttc tttggttaat tttatagatt tatttttttc atccaatatg atgttcttat
     8761 aatcaataag aggcagaagt ttttgtatct cagaatcact tggaacttta gctttatctg
     8821 ttccaatagc ccataaattt gataatggac caattgttat gtcaaaatat ccatctgata
     8881 atttggaata ttgtatagct tcttttacga cgaaaaatgt atcatcagaa actctgacaa
     8941 attttttacc agcattatca tttattttag aaacatcact tcctggtata tgagtgctca
     9001 ttttgttgtc aatatatctt aaaattgaat cacattcatt taagatttta tcacttttgg
     9061 attcttttac attaaataca gtaacttcgt ttactgtacc aaggtagtag ctagttttac
     9121 tatatttagt attctggctt gaactcctaa aaaatgaaaa taaaattaat gctaaaatca
     9181 atatcacaaa aataaatgtg atttttttct tattcatggt atattcctcc tatgaaattg
     9241 tgttattatt ttattataac ataatttcat aggaggacaa aaaatgaaga aaaaagacat
     9301 tcttcttatt ttaggcattt tggttgttat tacagcatgt tatgggataa taaatgttat
     9361 aaattctaaa aatgctggaa atattgagat ttatgtagat aataaattgt ataaaactgt
     9421 ttcaataaat gccaaagaag aatttaaaat agagaataga ggggggtata acatagtaaa
     9481 gattcatgat aaaggggttg agatagtaga tgcttcatgc cctgataagg tttgcgtaca
     9541 tactggattt ataaacaagc caagtcaaag catagtttgt atacctaata gagtgagcat
     9601 aaaaataaat acaaatgaaa agaatgataa tcaagaagat ataatttcta aataaaataa
     9661 taaaaataat tgaaaggaat tggtgataat tatggttaac ttaggaaacg attgggatga
     9721 attattgaaa gaagaatttg aaaaagatta ctacttaaac ttaagaaaat ttcttataga
     9781 agaatataaa acacgccaaa ttttcccaaa tatgcacaat atatatgaag ctttaaaaca
     9841 cacttcatac aaagacacaa aagtcttaat attaggacaa gacccttatc atggagataa
     9901 tcaagctcat ggtttagctt tttcagttca accacaagtg aaaactccac catctttatt
     9961 aaatatgtat aaagaattaa aagatgattt aggttgtttt atacctaata atggatattt
    10021 aatgccttgg gcagaccaag gagtgttact tttaaatact gctcttactg ttagagcgca
    10081 tgaagctaat tctcataaga acaaaggatg ggaaattttc actgatagag taatatctat
    10141 tttaagtgag cgtgaagacc cagttatttt tgtactatgg ggaagtaatg cacgtaaaaa
    10201 agtagagttg attgatacaa gtaaacatta tattttggaa gcacctcatc caagcccatt
    10261 gtcagcaagt aaaggctttt ttggatgtaa acacttctct aagataaatg aaattttgaa
    10321 aaagctagga aaagaaccta ttaattggca gatagaaaat atataaaagt aaaaggtaac
    10381 aaaatgataa caaaacaaca ataaacaatg acattgttgt aactaataga aatatgctta
    10441 aatagttgaa aatgctatgt atgcatattt ctattttttt gtcaagttga caactcttga
    10501 aaaaatagtt acaatttagt tacacaaaaa acacaaataa aaaaagaaac ttacaaagca
    10561 gaattttatg aagcaaaata tatagtgtaa aaaatcttag ggaggaaatt ttatatgaat
    10621 tttaaaaaat tgagtaatgc taaagtctcg gtaatggcag ttgttttatc agttggaata
    10681 ttatcgggat actctgcgct taataaacaa gtaacattag tagtaagggg agaagaaaga
    10741 actatatcaa catttagttc taatgtagga gaccttttag aatctcaaaa cattagctat
    10801 gatgcaaatg atatagtaac tttagatgaa aatacaaagt tatctaatgg agataaaata
    10861 gaagtaattg atgtaaagga aaaaacagtt gtagaaacta aagacattcc atttgaagtt
    10921 acagttgttg aagatggctc tttattaaag ggtgattcta aggttaaaga agaaggaaag
    10981 tctggtaaaa gtgaattaat atataaagaa acttatcaca atggaaagaa agtagaaaag
    11041 gaatttgtga aaaaggttgt taaagctgag ccagtaaata aggttgtaag caaagggaca
    11101 aaggtagaaa tgcaagtagc ctcatcaagg ggagaaagtt caagaagaat ggcttcatca
    11161 tcatctagta gcagtagtag taacaatggt aaaaatatga gagtggtagc aactgcatat
    11221 actggtcaca gtataactgc aacaggaaca aaacctaagt ggggaacaat agctgtagac
    11281 cctaaggtta taccatatgg aactaaagtt tatatacctc aatttgacat ggtgtttact
    11341 gcagaagact gtggtggagc aataaaagga aataaaattg atatctacat gaatgattca
    11401 aaaacagttt ataactgggg aagaaaaact atagatatac gtatattaaa atagttaaat
    11461 aatttatatt tttactggaa attatatctt gattatatag agaagaaact ctttatagat
    11521 tctaaaaata taatttccag ttttttattt tggatatgta ataaaacagg taaattttaa
    11581 ccatgtatag ataaaagcta tttaaattat aatttactat catataaatc tataaaaatt
    11641 gttgcaaaga gtcaaaatat atgatattat agatttcgtt gagaaggatt tcattatggg
    11701 agtggatggg tgccggtgtg ccctctagtc ttcaaaacta gtatgagggg ttaagagcct
    11761 cttaggtggg ttcgattccc acgcattccc gccaatatgt aaaaggtatc ttttaattaa
    11821 aagatacctt tttaaattta ttttaagata atttattttt aataatatat aatgttttgt
    11881 attatataat gtaaattttc taatactatt atatatttag ataaaaatct aggagtgtgg
    11941 aaagatggaa aataatttta caacgagaac tagttttcta gttggagatg atgggataaa
    12001 aaaacttaat aattcaaata taatagtatt tggagttgga ggagttggta gttttactgt
    12061 tgaagcttta gcaagagctg gagtaggcaa tattactatt gtagattttg atgatgtaga
    12121 tataaccaat ataaatagac aaataccagc cctacattca actgtaggaa gatacaaagt
    12181 tgatgtcatg gaagaaagaa tattagatat aaatcctaat atcaatataa aaaaaataag
    12241 aagtctttat aataaagata ctagtgacga aatactaact gaaagatatg attatgttgt
    12301 ggatgcgata gacatggtaa gttccaaaat acatctaatt gaaacttgtg aaaaaaaagg
    12361 attgaaaata ataagttcta tgggtatggg aaataaatta gacccaacta aaatagtcgt
    12421 tacagatata cacaaaacaa gtacttgtcc tttagctaaa gttatgagga aagaacttag
    12481 ggatagaggt atcaaaaagt taaaagtagt atattctact gaacaaccaa tagaacttaa
    12541 gaagaaagta atgaatggta gaaaagtaac acctggtagt gtatcatttg tcccatctgt
    12601 aggaggttta ataatcgcat ctgtaatagt aaatgaacta ttaggacaat aagttttaaa
    12661 tattttaatt tataaatttt atatacaaat ttgaaggcta gaagcatgaa tataaagcaa
    12721 ttttatattc atacttttag cctaattatt ttatattacc ttattttatg tagttgtagt
    12781 tttatttttt agattatgta tctatttcat aattatattt tgtaaatata atttctccat
    12841 cactataaaa aacaatatct cctattctat ctgttctata aattgataca tggttttgtt
    12901 ttagattatt aataacctcc ctatgtggat gaccatattg atttttatat ccacatgata
    12961 ttgcagctat atctggacta atttttttta taaattctaa agatgaagaa gaattacttc
    13021 catgatgacc tatttttata aaattaatat tatttaattt aaaagaatgt aaaatttctt
    13081 tttcattttc ttcttcagca tcacccataa ataaaaaaga attatcatta aaagttaatt
    13141 tgaaaactat agaatttaaa ttagattctt cttgtatata tgatggactt aatacatata
    13201 tatttatatt gttatctatg tttaaaacat catttttata gagatgctga atagataagt
    13261 ttttatccgt acaagaattt attagatttt gataagcctc actatcagtt gattgttcag
    13321 gcatatatat ggagtttaca ttaaattttt ttataatatt atcaagactt cctatgtggt
    13381 ctgaatctgg atgagttgct attataatat caatagtttt tattcttttt tgtctaagat
    13441 aactaataat tatattttcg ctatcttcat cacctccatc aattaatata ttcttatttg
    13501 tgggtgtttg aactaaaata ctatcacctt gtccaacatc aatcatatgt atagatagta
    13561 gagatttttt gtcacagccg attaaaagtg atattataat aagtattgat aaaaaaattt
    13621 tatttctcaa taaaaaatca ctccattcat tacatgttta tataaattta tgatgggtaa
    13681 tataagatat atatgactta ttatatttta tattttaaac aatataaatg aaattaatac
    13741 aataataaaa ttggagtttt ttatatatac aaaataaaat ttttaaaatt aagcaataaa
    13801 aaaggtagga ggattttatg tttttcaaag atattgaact aaattcaaaa aaagagttag
    13861 acccatattt tgatttagta gattatgaag cttgtgagta ctgttttagt actttatata
    13921 tgtggcaaca tgtttataag acaggatatt atataggtga agattttgcc gttttagttg
    13981 gggaatacga aggagatagc ttctcaatat taccacttgc taaaaaagat aaacttccag
    14041 aagttgtaga ttt
//
LOCUS       DAFAZV010000076        12526 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFAZV010000076 DAFAZV010000000
VERSION     DAFAZV010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12526
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.079"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(348..893)
                     /locus_tag="KOU88_003648"
     CDS             complement(348..893)
                     /locus_tag="KOU88_003648"
                     /inference="COORDINATES: protein motif:HMM:NF012798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK3213474.1"
                     /translation="MRVEPIENKKDIEKLKRYFRNKGKIRDLTLITLGLNTGFRIEDI
                     LKLRVKDVYKKREINIKESKTGKRIRKPINDSLKEILDIYCKDKPTNEYLFKSQKGEN
                     EAISTTQAYRIIKKASKACRIKLNIGTHSMRKTHGLHIFKDKGIEVAQRALNHANQID
                     TLTYIGVVQKQADNAIMKLNL"
     gene            complement(909..1157)
                     /locus_tag="KOU88_003649"
     CDS             complement(909..1157)
                     /locus_tag="KOU88_003649"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213475.1"
                     /translation="MEGTKRSYRKIPKLDLRKVKLADVFEKNKSGVFRVEEADEQLLH
                     ECLDETKSIREEKHLTWQIQFKGKSVYCVFYEHPFWDL"
     gene            complement(1144..2079)
                     /locus_tag="KOU88_003650"
     CDS             complement(1144..2079)
                     /locus_tag="KOU88_003650"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213476.1"
                     /translation="MINIIDLRFYLRNDLFTNEELTEITKQITEENVFLYDIAEEKGC
                     HPYTLNKCLQRFEHSSMEVGKFIGEMSELHKEGALTTEELKLKFEIVKEILILIKRSE
                     EAEKILHLLENEKVKTVAEKLYKSRSSVYDILKQMGFKKNKYINVWYHIDNENIAGNV
                     ENTKRDVELVHLYQQRYDNFLKNYYLDSEIIDIDKNILDDIETLSEEFEYETVNDFIS
                     VLLLRGLQNERFKNKENINNKNDNNNIVKMKDVEHEIFFTQGAEMLEEYYKTNLIDVH
                     KISKTEIEEMNPKELMELYHLKNEGKAKEDFYGRD"
     gene            complement(2250..2897)
                     /locus_tag="KOU88_003651"
     CDS             complement(2250..2897)
                     /locus_tag="KOU88_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003411768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK3213477.1"
                     /translation="MIIGYERVSTRKQDNSRQERVLENEGIKFDKIYRDKVTGATKER
                     EALNRMLLEVNEGDTVYCESISRLGRNLKDLIDIIDTLVQKGVRVKILKEGIDTGNNT
                     YKLLLGIFGAVAEMERETIQERTQQKIDQLKEDKKNTGEINTKSGKWFGRQKVTKELL
                     ETNKEFIKYYNKILDGSLKKNEVAKILNVGRTTLYEWIKVYEGGEIKRSNRAKKN"
     gene            complement(3487..3855)
                     /locus_tag="KOU88_003652"
     CDS             complement(3487..3855)
                     /locus_tag="KOU88_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004068822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213478.1"
                     /translation="MELDFKFIGQRIKIARIKKKLTQEVLSEKINVSPQHVSNIETGN
                     SSVSLPTLVAIANTLGVSVDELLCDTILSSKAVFENELEEVLRDCNEYEIRFITDIVK
                     ASKKSIRDIKLFQSNLNDRY"
     gene            3971..4303
                     /locus_tag="KOU88_003653"
     CDS             3971..4303
                     /locus_tag="KOU88_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213479.1"
                     /translation="MDIPKIPQTELKVMKFIWSKNDIVTSKEVAKAMELEYSWKMTTT
                     LTILSRLVIKHFLASERIGRMTHYTILIAKKDYKISETKRFLNDIHSNSLESLLNSLK
                     DCNITHKK"
     gene            complement(4451..4888)
                     /locus_tag="KOU88_003654"
     CDS             complement(4451..4888)
                     /locus_tag="KOU88_003654"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213480.1"
                     /translation="MRVKNIISIFVCALIIIMSVNVVSFAEQFNSSDIIFMEDGKEEI
                     NPFSVYILNGRCNLSFSNGKANVNASVVGKSGVTRTSIVTKLQELKGGSWVNLKTSTK
                     KTGGKTCSVLNSYSVTKGHTYRAVAIITAENESKTLISTSQKY"
     gene            complement(4957..5658)
                     /locus_tag="KOU88_003655"
     CDS             complement(4957..5658)
                     /locus_tag="KOU88_003655"
                     /inference="COORDINATES: protein motif:HMM:NF025643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4367 domain-containing protein"
                     /protein_id="HBK3213481.1"
                     /translation="MNKDKLDIEKLLYEQLPKIEEKILYELPCDEDIDYEFSIEFESK
                     MDKIIKENEKKVKKNTYKNLKKIAIVFIIILSSIVTITTIKTEAFPENLIRIMKKVYK
                     EFTDYNFINPHKSNVSFKYIEPKYISTGYKEVERIEEENYLSILYKDKLDNYIIYQMM
                     LYSRDVIVLDTEDAFVENIKFNNQYAQYVEKGNTQQLLWHDKNNIYMLSKELPTKKIT
                     KKDKKEFIKIAKNIK"
     gene            complement(5651..6196)
                     /locus_tag="KOU88_003656"
     CDS             complement(5651..6196)
                     /locus_tag="KOU88_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3213482.1"
                     /translation="MLIYLAIIDSKEERIKFEEIYIKYKKLMFYVANQILKDDVLAED
                     AVHSSFLKIIDNLDKVNDVNSPKTKGFVVIIVKRISINIYNRRKKEEISNINDDNYKF
                     SSLDLSIEKLGECSYLGEALKKLSETDLQVILLKYSHGFSIREISKLLNIKEVNLYKR
                     NKRALEKLKKILSEMEALSNE"
     gene            6332..7060
                     /locus_tag="KOU88_003657"
     CDS             6332..7060
                     /locus_tag="KOU88_003657"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213483.1"
                     /translation="MKSKRINKMLATTMTMAMLAIPAVTATSYAMESTGLGTEYTYNN
                     ESKQQEEWVKSFDTETGKEILLNKTTNEKVSEVYENVNGKLVKLSINEALEKFNLNEE
                     IITKSPKSIFGVSSVKKITGSARKISQDVSGGKQGATISIGNSTTVTESFTVGGTTEA
                     IKAAVRANAGFTWSKSLTRSVTTTHKVPAGKIGYVAFKPYYKEVRGTVNGILAGTSIT
                     QKIVAKSPLKAGKVCDGLEYLAYK"
     gene            7086..7334
                     /locus_tag="KOU88_003658"
     CDS             7086..7334
                     /locus_tag="KOU88_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004035436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213484.1"
                     /translation="MENKNMYLRVSLILAVLGFIILFFNNDLALSLKATYLADKGFED
                     IVENQILKNYSYMFLIIGGVLFSIGIYNLTKLKQINKK"
     gene            complement(7520..10129)
                     /locus_tag="KOU88_003659"
     CDS             complement(7520..10129)
                     /locus_tag="KOU88_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK3213485.1"
                     /translation="MKIDIKQLIDIIKNANIDELYLRDIGVDTTQKRNVPCPIHGGKD
                     KNFQFDLNKRIYTCYSHNCVVGADIIELCRTYERFERPIEAILFLANKYNISLPINKS
                     KTNIKKTNNTIKNIYIKKKDINSFIEEKKQEAFKNNDIELAFEFECMTDKDKRKYYLD
                     NNIKIKSMLEKQNYSSYKADSIINIDKYISENLKGIRESIKHATEGKNVLMVAPTGSG
                     KTYSIINTLKELDIKALFIFPNSANVQQAIVEYKIAGAYDKIPTKHALEGNKLVAMTW
                     DKTEQLLKEDLSEYIIVIDEIHQTYTDAFRSKAIKSLNNITNKCRGRLDITATPSKLE
                     FEIYNKVIEYKQNIQTEYKVKLYDKINIGKVIEILNNSNNSMLLKDSISTLNYISKKV
                     NKKSGVVISDTKDTSKLYDRIVSYSDMEGYEVLLNTSVITAGVNINNPNVTDIIVIGE
                     KDVGKIKQYVARARGAKSINVHIFNSYKTTNEDSNVYSVEWCINENIKDVESLTNIYN
                     KASKRDLPYRAIGIDISPINIKNIDSNIYYDKKDMCYKTDKLYIKSNAYNNYYQTRTI
                     NSFKVLLEEYFNKIEIVETEKETKKIEEEIKEHEEAIKEFKKSAIEQLEGHKKYLVGY
                     SEIKKSMTSSNLLKYHHDMRIDNNICLKYYMEHDLYSLIINNNCRKTIDLFSDFVLDN
                     SYSIDLSWKLATMSDEKRNLFFEQINTTIYRKINKKYANSLLNDDNIGTYTYNYINFN
                     FGVGTSYTKEHLEALAVDLQTFLATKKKLTIKKISLILQSIFVIEVKQHRGVTGLPYK
                     YYKNILPNPVTDKKVIRVYTIKKHIDIEDIKKELGLIDNDLSIEHLVEARINKLLNAI
                     DETEKEVLLEGLI"
     gene            complement(10459..10761)
                     /locus_tag="KOU88_003660"
     CDS             complement(10459..10761)
                     /locus_tag="KOU88_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213486.1"
                     /translation="MLKDDLLRIGFDTYGVNLEDKLLENNEIYLNDKKESERIMNRLL
                     EILEEKEHKKMLIDFEEKVFGNSVIEKEYAYRMGVLDGLDLAEFIDLNKKLCLKRN"
     gene            10930..11133
                     /locus_tag="KOU88_003661"
     CDS             10930..11133
                     /locus_tag="KOU88_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003366523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213487.1"
                     /translation="MDIQINKLLENQNKTRYWLAKQIGMTHQNLTKLANNNTNSIKFD
                     SLEKICMALKCSPNELFGWEQDK"
     gene            11213..11758
                     /locus_tag="KOU88_003662"
     CDS             11213..11758
                     /locus_tag="KOU88_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011572951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213488.1"
                     /translation="MDRYTFDNLPIKEQIQYINNKLLEGNTLTNTCKDIGIGRTTIRN
                     RFKQHGYEFNPTKKLYISIIEVVELESSSKVVAGDTSNDNTLVDATNIDFNNILSKFN
                     DMNNKLNEVYSWYESQSSNKVVGADKLNIDDFKGNIVVRSYKVYEDIQKEFVAFCEAN
                     KKYRVQDIISQALRDFMDKYK"
BASE COUNT         4134 a         1982 c         1342 g         5068 t
ORIGIN      
        1 aaaaaaaaat aaccatacgc attgatttta cttaaattaa aagtgttttt cgagttgttt
       61 tttcacttag tttagtaatt ttgaaatatt ataatattaa gcttcaatat gtatctatta
      121 tcatttaata atcaattaat aatagatatt ttttctaaac aagataaaaa caatatctat
      181 accagtaata gcaatagata gaagtatata aaaaaatgta cgattactat aaactattac
      241 atttatttta gttgccttga tacattgcaa ttacttacac atacgcctat ttaattaatc
      301 attaactata aaatgtaaaa acagcaaaga aaatcataca tttttaacta taaattaagc
      361 ttcataatgg cattatcagc ttgtttttgt actaccccaa tataagttaa tgtatctatt
      421 tgattagcat ggtttaaagc tctttgtgct acttcaattc ctttatcctt aaatatatgt
      481 aaaccatgtg ttttcctcat actatgagta cctatattta attttattct acaagctttt
      541 gaagcttttt taataattct atatgcttgt gtagtgctta ttgcttcatt ctctcccttt
      601 tgacttttaa ataaatattc attagttggt ttatctttgc aatatatatc taatatttcc
      661 ttcaaactat catttatagg ctttcttatt cttttccctg tcttactttc ttttatattt
      721 atctctcttt tcttgtatac gtctttaact cttagtttta gaatatcctc tatcctaaag
      781 ccagtattta accctaaagt tattagggtt aaatctctta ttttaccttt atttctaaaa
      841 tatcttttaa gcttctctat atctttttta ttttcaatgg gctctactct catttaaacc
      901 actcctattt ataaatccca aaatggatgt tcataaaaaa cacaatatac acttttccct
      961 ttgaattgta tttgccaagt aagatgcttt tcttctctta tacttttagt ttcatctaaa
     1021 cattcatgta aaagttgttc atcagcttct tccactctaa aaacgcccga tttattcttt
     1081 tcaaatacat ctgctaattt tacttttctt aaatctaatt ttggtatttt tctataactt
     1141 cttttagtcc cttccataaa aatcctcctt agcttttcct tcatttttta aatgatatag
     1201 ttccattaat tcttttggat tcatttcttc aatttctgtt tttgaaattt tatgaacatc
     1261 tattaaattt gttttataat attcctctaa catttcagct ccctgtgtaa aaaatatctc
     1321 atgttcaaca tctttcattt taacaatatt gttgttatcg ttcttattgt taatattttc
     1381 tttattttta aatctttcat tttgaagccc tcttaaaagt aaaaccgata taaaatcatt
     1441 tactgtttca tattcaaatt cttctgacaa agtttctata tcatcaagaa tatttttatc
     1501 tatatcaata atttcactat ctaaataata gttttttaaa aaattatcat atctttgttg
     1561 atacaagtgt actagctcaa catccctttt agtattctca acatttcctg ctatattttc
     1621 attatcaata tgataccaaa cattaatata tttatttttc ttaaatccca tttgttttaa
     1681 aatatcatat acacttgacc ttgatttata cagtttttct gcaactgtct tgaccttctc
     1741 attttccaat agatgtaata ttttttcagc ttcttcagac ctttttataa gtattaatat
     1801 ttcttttaca atttcaaatt ttaatttcaa ttcttctgtt gttaaagctc cttccttatg
     1861 taattcactc atttcaccaa taaatttccc aacctccatt gatgaatgtt caaacctctg
     1921 taagcattta tttaaagtgt atggatgaca gcctttttcc tctgcaatat catataaaaa
     1981 cacattttct tctgttatct gcttagttat ttcagttagt tcttcattag taaataaatc
     2041 atttcttaaa taaaatctta aatcaattat attaatcact cctttttaat tatttttcat
     2101 acattaatct tatcaccaaa aaaattaaat ttaaatattc caagacatca tctggacgct
     2161 aaaaagtgtc gtttttatta atttaataat attatcaaaa aaaagagcaa agacagtccc
     2221 ctaaaataaa aaaagaacta gttataaccc tagttcttct ttgctctatt gcttcttttt
     2281 atttctccac cttcatatac ctttatccac tcgtaaagcg tagttctacc aacatttaat
     2341 attttcgcca cttcattctt ctttaaactt ccatcaagaa ttttattata atattttata
     2401 aattctttgt tggtttctaa aagctccttc gttacttttt gtctaccgaa ccattttcca
     2461 ctctttgtat ttatctcgcc agtatttttc ttatcctctt tcaactggtc tattttctgc
     2521 tgtgttctct cttgtattgt ttccctctcc atctctgcaa cagctccaaa tataccaagt
     2581 aataacttat aagtattgtt tcctgtgtct ataccttctt ttaatatttt tactcttaca
     2641 cctttttgaa ccaatgtatc tataatatca attaaatcct ttaaatttct acctagacga
     2701 cttatagact cacaataaac cgtgtccccc tcatttactt ctaacaacat tctatttaat
     2761 gcttctcttt cttttgtagc tcctgtgact ttatccctat atatcttgtc aaacttaata
     2821 ccctcatttt ctaaaactct ttcttgtctg ctattatctt gttttcttgt acttaccctt
     2881 tcatatccta ttatcataac actacccccg tttatcttgt tataataatt atacaatata
     2941 ttttccgttc ggtcaaacta tattttctat tttcacaata ccgaacgtat tttattgttg
     3001 atttccaatg attctatgta aaaataacat aaatatcata cgtacggtta aacgttggtt
     3061 tttccgaaca cgaacatatc acctttttta tatcaactat tccttaaata ttttatataa
     3121 aatcgccaaa atctttttat attttttagg caaccaagtt tttaaaacaa aaatggtata
     3181 tcagtaagaa ttatgttttc acacaatata attcttaatg atataccatt taagaacctc
     3241 ataagaggta gatagagata attacataat catcacatac gttttatcaa atctgttttg
     3301 taatagggtt tatacttaaa taataacaaa aataccgtat tttttctaca tttatacttt
     3361 ttttgttgat agtaaaatat ggaaattagt catattttca gttattaact cataagttta
     3421 tacaactttt atttaaatat aataaaaaca tcaataataa ttaaattatt gaagcatata
     3481 tttatattaa tatctatcat ttaaatttga ttgaaacagt tttatatctc taatggattt
     3541 tttagaagct tttacaatat cagttataaa tcttatttca tactcattac aatccctcaa
     3601 aacttcttct aactcatttt caaagacagc tttagaactt aagattgtat cacataataa
     3661 ttcatcaacc gacaccccaa gagtatttgc aatagcaacg agcgttggca aacttacact
     3721 tgaatttccc gtttcaatat tgctgacatg ttgtggacta acattgattt tttctgataa
     3781 aacttcttgt gttagctttt tcttgattct tgcaattttt atcctttgac ctataaattt
     3841 gaaatcaagc tccatatgcg tattcccttc ctacaagtat tcacacatat tgtaaccttt
     3901 cccaaagtat attataataa attaatagaa tgtttcatta tgatagttat agtgtataga
     3961 aaggaattat atggatatac caaagatacc tcaaacagaa ctcaaagtca tgaaatttat
     4021 ttggagcaaa aacgacattg taacatctaa agaagttgca aaagctatgg aacttgaata
     4081 tagttggaaa atgacaacaa ccctaacaat cttatcaagg cttgttatta aacacttttt
     4141 agcatctgaa cgaataggca gaatgacaca ttatacgata ctcatagcaa aaaaagatta
     4201 taaaatatct gaaacaaaaa gatttctaaa tgacatacat tcaaattcat tggaaagcct
     4261 tttaaactct ttgaaagatt gcaatattac acataaaaaa tagtacatga gtataaatta
     4321 tattattata cctatgtact atttaagttt ttctataatg ttcctatatc tatctaattt
     4381 tgattgattt agatacttct gtagtagttt tcaaaacgtt tcttaactct tgtaagtgta
     4441 ttttcttttt ttaatatttt tgagatgtac ttattaatgt ttttgactca ttttcagcag
     4501 taattattgc aacagctcta taagtatgtc cttttgtcac agaatatgag tttaaaacag
     4561 aacaagtttt tcctccagtt ttctttgtag atgtttttaa atttacccaa cttccgcctt
     4621 ttaattcttg taacttagtt acaatagatg ttctagttac tccagatttt ccaacaacag
     4681 aagcatttac atttgctttt ccattagaaa atgataaatt acatctacca tttaatatgt
     4741 aaactgaaaa aggatttatt tcttctttac catcttccat aaaaataata tcagatgaat
     4801 taaactgttc agcaaaacta acaacattta ctgacattat tattatcaac gcacatacaa
     4861 atattgagat tatatttttt actctcatta agtacctcct tataaaatct tatatattca
     4921 atataacaac taactagcac tattttagac aaaaatttac ttaatatttt ttgcaatttt
     4981 aataaattct tttttatctt tcttagttat tttttttgta ggtagctctt tagataacat
     5041 ataaatatta tttttatcat gccacaataa ttgttgagta tttccttttt caacatactg
     5101 tgcatactga ttattaaatt ttatattctc aacaaaagca tcctctgtat ccaagactat
     5161 aacatcccta gaatataaca tcatttgata aattatatag ttatctaatt tatctttata
     5221 taatattgat agataatttt cttcctcaat tctctcaact tctttatatc cagtagaaat
     5281 gtatttaggt tctatatatt taaatgatac atttgattta tgagggttta taaaattata
     5341 gtctgtaaat tctttatata ccttcttcat tattctaatt aaattttctg gaaaagcttc
     5401 tgtttttata gtagttatag tgactatact tgataaaatt attataaaaa caatagcaat
     5461 tttttttaag tttttatagg tgttcttttt tacttttttc tcattttctt ttataatttt
     5521 atccatttta ctttcaaatt ctatagaaaa ttcatagtca atatcttcat cacaaggtaa
     5581 ttcatacagt attttttctt ctatttttgg aagctgttcg tataataatt tttctatgtc
     5641 taatttatct ttattcattt gataatgcct ccatttcgct taaaattttt tttaattttt
     5701 ctaatgctct tttatttctc ttatacaaat taacctcttt tatattcagt agtttagaaa
     5761 tttctctgat agaaaaacca tgactatatt ttaagagaat cacctgtaaa tctgtctctg
     5821 acagtttttt taaagcttct cctaaataac tacactcacc taacttttca atcgataaat
     5881 ctaaagagct gaatttatag ttatcatcat taatattact tatttcctct ttttttcttc
     5941 tattatatat atttattgaa atccttttta ctataataac aacaaaacct ttagtttttg
     6001 gactattcac atcatttact ttatcaagat tatcaattat ttttaaaaat gaactatgaa
     6061 cagcatcctc cgctaaaaca tcatctttta aaatttgatt agctacataa aacattaatt
     6121 tcttatattt aatatatatt tcttcaaatt taattctttc ttcttttgaa tctataatag
     6181 ctaaatatat taacataaat tattctccct taaaaaatat tatccttaaa aaaattatat
     6241 acaatttata aaaaattata tataaatgtc taaaaataaa aacttcattt gttatatata
     6301 taaataaaaa cataaaagga tggtgtttta tatgaaatca aaaagaataa acaaaatgtt
     6361 agcaactaca atgacaatgg caatgctagc aataccagca gtaacagcaa catcatatgc
     6421 aatggaatca acagggttag gaacagaata tacatataat aatgaatcta aacagcaaga
     6481 agagtgggtt aaatcattcg atactgaaac aggaaaagaa atattattaa ataaaactac
     6541 taacgaaaaa gtttctgaag tatatgaaaa tgtaaatgga aaattggtta aattaagtat
     6601 taatgaagca ctagaaaaat ttaatttaaa tgaggaaatt atcacaaaat ctcctaagtc
     6661 tatttttgga gtatcaagtg ttaaaaaaat tactggttct gcacgcaaaa tatcacaaga
     6721 cgtatcaggt ggaaaacaag gtgctactat atctatagga aattcaacaa ctgtaactga
     6781 aagttttact gttggtggaa ctacagaagc aataaaggca gcagtaagag caaatgcagg
     6841 atttacatgg agcaaatctt taacaagaag tgtcacaact acacacaaag tacctgcagg
     6901 taaaatagga tatgtagcat ttaaaccata ttataaagaa gtaagaggta cagtaaatgg
     6961 gatacttgca ggaacttcta taactcaaaa aatagtagca aaaagtcctc ttaaagcagg
     7021 aaaagtttgt gatgggttag aatatcttgc atacaaataa taaataatag aaagagttga
     7081 ttaaaatgga aaataaaaat atgtacttaa gggttagttt aatattagca gtattaggct
     7141 ttataatatt attttttaat aatgacttag cattatcact aaaagcaaca tacttagctg
     7201 ataaaggctt cgaagacata gttgaaaatc aaatattaaa aaactattcc tatatgtttt
     7261 taataatagg tggtgtacta ttttccatag gaatctataa cttaaccaaa ctgaaacaaa
     7321 ttaataaaaa ataaataaaa taagaggact tataaattat aagtcctttt attttacact
     7381 tataagctac tttcaacctt tcatgattta acctttattt atacaacacc caaaactcga
     7441 cctcaaaaag agaacaggac ttcgtccccc ttaatacaaa gcaacatttt ttagtactat
     7501 tcgtacttaa gattagctat tagattaatc cttccaaaag aacctctttt tccgtttcat
     7561 caatcgcatt taaaagttta tttattctag cttcaactaa atgctctatg cttaaatcat
     7621 tgtctattag tcctaattct ttttttatgt cctctatgtc tatatgtttc ttaatagtgt
     7681 aaactctaat tactttttta tctgtcacag ggtttggaag tatattttta tagtatttat
     7741 agggcaaccc tgtgacaccc ctgtgttgtt tgacttcaat aacaaaaatt gattgtaata
     7801 ttagacttat tttcttaata gttagctttt tcttagttgc taaaaacgtc tgtaaatcaa
     7861 cggctagagc ttctaagtgt tcttttgtat aacttgtacc aactccaaaa ttgaagttta
     7921 tataattgta agtataagta ccaatattat catcatttag caaagaattt gcgtattttt
     7981 tattaatttt tcgataaatt gttgtattta tctgttcaaa aaatagattt cttttctcgt
     8041 ctgacattgt cgcaagtttc caagataggt caatactata actattatct aatacaaaat
     8101 cactaaataa gtctatcgtt tttctacaat tattattaat tattaggcta tataaatcat
     8161 gttccatata atattttaaa cagatattat tatctatcct catgtcatga tgatatttta
     8221 ataagttact gctggtcatt gacttcttaa tttcactata gccaactaga tactttttat
     8281 gtccttctag ttgttctata gctgatttct taaattcctt aatagcttcc tcatgctctt
     8341 ttatttcttc ctctattttt ttagtttctt tttcagtttc tactatctca attttattaa
     8401 aatattcctc taatagcact ttgaagctgt ttattgttct tgtttggtaa tagttattgt
     8461 aagcattact ttttatgtat aacttgtccg ttttatagca catatctttt ttatcatagt
     8521 atatattact atcaatgttt tttatgttta tagggcttat atcaattcct atagctctat
     8581 atggtaagtc tctcttagaa gctttattgt atatatttgt taggctctca acgtctttta
     8641 tgttctcatt tatgcaccat tcaaccgaat atacattgct atcctcattt gtcgttttgt
     8701 aactattaaa aatatgtaca tttatacttt ttgcccctct agctcttgca acatactgtt
     8761 ttatttttcc tacatccttt tctccaatta caataatatc tgttacatta ggattattta
     8821 tgtttacacc tgccgtgatt acagacgtat ttaaaagcac ctcatagcct tccatatcgg
     8881 agtaactaac aattctatca tatagtttgc tagtgtcttt agtatctgaa ataacaactc
     8941 cactcttttt attaactttc tttgatatat agttaagtgt tgatatacta tcttttaaaa
     9001 gcattgaatt atttgaatta tttagtatct ctattacttt cccaatattg attttatcgt
     9061 ataacttaac tttgtattcc gtttgtatat tttgtttata ttcaataact ttgttatata
     9121 tctcaaattc taatttagag ggtgttgcag ttatatctag tctacctctg cacttattag
     9181 ttatattatt taagctcttt attgctttgc ttctgaacgc atctgtgtaa gtctgatgta
     9241 tttcatcaat aactattatg tactcgctca aatcctcttt tagaagctgt tcagtcttat
     9301 cccacgtcat agccactaac ttgtttccct ctaaagcgtg tttagtaggt atcttatcat
     9361 atgcaccagc tattttatat tcgactattg cttgttgcac attcgcagag ttggggaata
     9421 taaagagtgc ttttatatcc agctctttta atgtatttat aattgagtat gtttttccac
     9481 ttcctgtagg agctaccatt aatacgttct taccttctgt agcatgttta attgactctc
     9541 taataccttt tagattttca cttatgtatt tatctatatt aattatcgaa tcagctttat
     9601 aacttgaata gttttgtttt tctagcatgg attttatttt aatattgtta tctaagtaat
     9661 actttctttt gtccttatca gtcatacact caaattcaaa agctaactca atatcattgt
     9721 ttttaaaagc ttcttgtttc ttttcttcta tgaagctatt tatatctttt ttctttatgt
     9781 aaatgttttt aatagtatta tttgtttttt taatatttgt cttactcttg ttaattggta
     9841 atgagatatt atatttattg gctaggaata aaatagcttc tataggtctt tcaaagcgtt
     9901 catatgtgcg acataattca attatatcag caccaacaac acaattatgg ctatagcatg
     9961 tatatattct tttgtttaaa tcgaattgga agtttttatc cttaccacca tgaattgggc
    10021 aaggaacatt ccttttttga gttgtatcga ctcctatatc tcttaaatat agttcatcta
    10081 tattggcatt ttttattata tcaattaatt gttttatatc tattttcatt tgtaaaaatc
    10141 cccctttttt agttaggggc taatcaagtt ttatcaagct atgtatttac attctgccgt
    10201 aaatctcgta taattaacat ataaaagaat aaggaaatat atattttata tgttaattaa
    10261 gcctaagtga ttagctccta gtattaaccc ctagtggcta actcctaatc ttgattaacc
    10321 cttaaatgga aagaatgagt ggatgccgtc aaacaaatac tcgttctttt tcgttttttt
    10381 tgttattagt attatatcac tattaaagtt ataattcatt gtttagaatt atttttctga
    10441 cggttttaat atatattttt aatttctttt caagcataat tttttattta agtctataaa
    10501 ttcagctagg tcaagcccat ctaaaacccc cattcggtat gcgtattctt tttcaattac
    10561 actgttacca aatacttttt cctcaaaatc aattagcatt tttttatgtt ctttttcttc
    10621 caatatttct aacaatctgt tcattattct ttcagattct tttttgtcat ttaaatatat
    10681 ttcgttattt tctagtagtt tatcttctaa atttactccg tatgtgtcaa atccaattct
    10741 taataaatca tcttttaaca ttacttttaa cactcctttt tatgcacact taaatctttt
    10801 gcacccctaa atatggtaat atattctatt tattattatg taattattta ctatgtattg
    10861 tcaagcatat atattgtttt tggtacatat ttccgatact atataataaa aaaggtggcg
    10921 attaaattgt tggatataca aataaataaa ttattggaaa atcaaaataa aacacgttat
    10981 tggttagcaa agcaaattgg aatgactcat caaaacttaa ctaaactagc caacaataat
    11041 acaaattcta ttaaatttga ttctttagaa aaaatttgta tggctctaaa atgttctcct
    11101 aacgagctgt tcggttggga gcaagacaaa taaaaaaata taaatcctaa agggtttatt
    11161 tataactact agaaaactac tttagtagtt attttatttt ggaggtttaa acatggatag
    11221 atatacattt gataacttac ctatcaagga gcaaatacaa tatattaata acaagctctt
    11281 agagggcaat acattaacta acacatgtaa agatattggt attggtcgta caactataag
    11341 aaatagattt aaacaacatg gatatgaatt taatccaact aagaagctat atatatctat
    11401 tattgaggtt gtcgaattag aaagtagttc aaaagtagtt gcgggcgaca ctagcaatga
    11461 caatacttta gttgatgcaa ccaatattga ttttaataac attttatcta aattcaatga
    11521 tatgaataat aaactaaatg aagtatatag ttggtacgaa tcacaaagta gtaataaagt
    11581 agttggggct gataaactaa atatagacga ttttaaaggc aatatagttg ttagaagcta
    11641 taaggtctat gaggatattc aaaaagagtt tgtagccttc tgtgaagcta ataagaagta
    11701 cagggtacaa gatattatca gccaagctct tagggatttt atggataaat ataagtagtt
    11761 ttacttactt tctgatattc taaaaacttt tcaatgaaaa tctcattttt tggcttcctg
    11821 tgaaaaatat gtactccttc cagtcctcta tctttattta ctttattaat ccgatagggg
    11881 gcgtattata tatatttcta tcgagcatat actcatcaaa acatagcatt agtttgatta
    11941 ttatatttct atttatttta agattatata tacaatttgc cccttaatac attgcaatta
    12001 ctaacttctt tagttttgat attaatattt aaatcattcc tttttaaagg tgctataagt
    12061 gctatatagg cattgcaacc tatatacttt ttaggggtgc agttgcatat gcaagctctt
    12121 tatttcccaa cacttaacca gttataaata tttatatcct ttattagcca aatatagcat
    12181 tttaaacaac tccgactatc tttagtagta acattttaca tagctttatt aatgtatttt
    12241 tgcatctgca accatgtttt taagttgcaa caccccaccc ccacacctta cacaaaacaa
    12301 tacttatctc cgaagccata tacctacctc ggttcacata tttttcttca acagcgttat
    12361 tttcagcaag gggggctaaa cattatactt tttttcagtg cattaaatag ccttacatgt
    12421 attggtataa ctttatttca aacccttaat tgaattgttt caatctaaat taagtaaatt
    12481 ttaataagat aaaatatata gtttgtaact ttatttcaaa atacag
//
LOCUS       DAFAZV010000077        12158 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFAZV010000077 DAFAZV010000000
VERSION     DAFAZV010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 12158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12158
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.080"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..396
                     /locus_tag="KOU88_003663"
     CDS             <1..396
                     /locus_tag="KOU88_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3213489.1"
                     /translation="LKTGKFIFHKVGDEVHVLEDINTFVSFTDEKNDDFSSNQSIRVL
                     DQIANDIATLFNHKYQGAVPNDKSGRISFWNDVVKHHEQLQNMRAIEDFKADDVSVEP
                     GNDKKTVVVSDAVKVISAMSKLYMTVSVS"
     gene            417..893
                     /locus_tag="KOU88_003664"
     CDS             417..893
                     /locus_tag="KOU88_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBK3213490.1"
                     /translation="MSKNITMNVRDAISGSKAECFVTIKGKRYNFMQAINLEAKMEKN
                     KSEMPILGSITKGNKSTGSKFSGSATFYYNTSIFRELLYEYKETGEDIYFDMQITNED
                     PTSSVGRQTIILEDCNLDSGIIAKFDADGEYLDEDVDFTFENWRIVEKFNIANGME"
     gene            947..1204
                     /locus_tag="KOU88_003665"
     CDS             947..1204
                     /locus_tag="KOU88_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213491.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFEINEAGVATIEKQTKYLIMEVE"
     gene            1206..1646
                     /locus_tag="KOU88_003666"
     CDS             1206..1646
                     /locus_tag="KOU88_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213492.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKPIEWELKAIDSD
                     RDRQLRKNSAIRVPVIGKKGKATGQYTSETDFNTYTLKLCVETIVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            1972..2124
                     /locus_tag="KOU88_003667"
     CDS             1972..2124
                     /locus_tag="KOU88_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213493.1"
                     /translation="MDNFLFNVLASVTASYIVYLISKLIKKVKSHSTAKSDLKIDINF
                     KYHRKK"
     gene            2628..3398
                     /locus_tag="KOU88_003668"
     CDS             2628..3398
                     /locus_tag="KOU88_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBK3213494.1"
                     /translation="MGLFGSKDNCCICGEKGKQKIADGWLCKECFKKYAVATFTPGNT
                     LYRGLPTKLEVEKAIESKDDKEKELKNFNPTKKILKFMEFDDNNKKFIVLNGFNREKV
                     NLNVYNYSDVIEYELLENGETVTKGGIGRALAGGALFGGVGAVVGGVTAKRTTKAFID
                     SLKIKITLNNLSNPNVYVNLIQLRTKSNSSIYKMAYSSAQEILSVLAIIVKDNEAVNI
                     QNNSNDAIQQVKGLKELLDLGAITDEEFNTKKKELLNL"
     gene            3465..5807
                     /locus_tag="KOU88_003669"
     CDS             3465..5807
                     /locus_tag="KOU88_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBK3213495.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMNNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIRESDNQQRRLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLSMINDGQQSDAGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTFSQIWTSIKNNAIMIFGVIQKKIEQSMSSKGFRTFIDNFINSLYVLGNVAYNI
                     FNGIISILGSPAFQSFSNTMIVGISLISQALGWIITQALNLANIFAQNWSIISPVILG
                     IVGALTLYKTAVLGLAIANSIALLSQKWFDFQLAQTAIMHDLATGATWRQIIAQYGLN
                     AALYACPLTWVVLGIIAVISAVFILVAVYNHFAGTSISVISLAVGAWYWLCAVVYNVI
                     SGIVNAINICVVGIANAFRTGLYAVQCFFIDMANAGLKAGVNLDKAFDKFATNLANGI
                     IKAVNIAVKGLNWLVEQINKIPGINLPQMKEFQKVNTVIGTKTTFKPIQKPPEPKAWK
                     PELVEYKNLKSEFIKGYDVGHQLQNKLKDTFDISKIAEDAKKKLGLDDLWDKKYGLGN
                     GFGSAGLNSPLGDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVN
                     IKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            5823..6524
                     /locus_tag="KOU88_003670"
     CDS             5823..6524
                     /locus_tag="KOU88_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK3213496.1"
                     /translation="MAYDFYLDGVQLPIAPPKLEVKVTNKNKTVDLINVGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFKDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNIKVSLEEYAISEDAENGSDTKVAIKLKQYRDYSTKKLVIAPPKNETGRPNVKIEPK
                     RVDSVNATNTKTKTKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKSMMDKANKGKK
                     VPKYTIYKGQVLKLG"
     gene            6517..8487
                     /locus_tag="KOU88_003671"
     CDS             6517..8487
                     /locus_tag="KOU88_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK3213497.1"
                     /translation="MDDELVLANDRDVRLVIAHWEDFYEPAVLDNITWEIERRGSPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRVEENKTLFDMVLTALDDTLRE
                     KKEMYVLYDDFGRITLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TSKRDVYIAQDSAHIRSWGVLQLFETVDKNMSEAEIKQKCDILLKLYNRKTKTLSLKN
                     VLGDIRVRAGCLVPVFLSLGDIDLQNYMLVEKVKHTFENNSHFMDLTLVDGDEFASYS
                     SSSYSSGNTNNKNEKQNGPAQSTTSKEDTDMANKINKLLKGKLSNTGNIFVKYSNAYK
                     VNPALMAAISMHESARGTSNIANTKNNFFGMKKNGDYMSFSSVDEGIKRGISNLSRNY
                     IHIGRKTLESIRNKYSSSSDKEWVKCVGAFYKQITGSTYNSNSAGTGVGSNEEAEKNL
                     KDLTYQVQNNNSNTSTNNNNKVSKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAFK
                     RGAGINLKRVSADQSKDSRGKLLCNINDVKAGDLVFFAYNKGKGNVHHVGLYIGNDQY
                     IHAPQTGDVVKISSLSGRQKKKHDFARARRFF"
     gene            8501..8761
                     /locus_tag="KOU88_003672"
     CDS             8501..8761
                     /locus_tag="KOU88_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBK3213498.1"
                     /translation="MSQELLQIIKKAAMDAVETSNPMQIAFGTIESVNPLIVKIEQKA
                     SFEEFFLIQTETFKRYTDKKIGDKLVLIRMQGGQQYLILDRM"
     gene            8766..9185
                     /locus_tag="KOU88_003673"
     CDS             8766..9185
                     /locus_tag="KOU88_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBK3213499.1"
                     /translation="MLPSDNLDYDIEDVSIINFDVRQEPSKTFKLNIEKSKIDGICDD
                     VEALKQTIFLILNTERYEHLIYSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDR
                     VENVDNFEFQNVKGKVHCKFTVHSKYGNIKAEKVVSV"
     gene            9186..10235
                     /locus_tag="KOU88_003674"
     CDS             9186..10235
                     /locus_tag="KOU88_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBK3213500.1"
                     /translation="MFELMTFENIIKRMLDSVPDTFDKREGSIIYNALAPVAIELTET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPIDSRFNLGE
                     YNYIATERIGEGIYKMKCETAGPIFELGQLIPIEYVDKLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNIQNYKDEVNKLPDVGGVKVYPVWNGGGTVKLVIINSNFKV
                     PSEDLVNLVQEEIDPIGHQGQGLGLAPIGHRVTVEGVTSTTINISAEITYKNSYTWEN
                     IKSIAEEAVDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDITNTMINDVKSNL
                     TIDSNSIVTRGEVIG"
     gene            10228..10845
                     /locus_tag="KOU88_003675"
     CDS             10228..10845
                     /locus_tag="KOU88_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBK3213501.1"
                     /translation="MDKKINLINYLPQVLQDKEEYIKVFNAENKEIKTLHDKLDDVLN
                     DQFLEDLTPSGVKRWEKIMSITPKSNETLEDRRFRIFSRYISKLPYSERFLRNWLDNI
                     VGEGNYELTINNSTYNIHLESDARNQDWFEEVHSFVSSIKPCNMSLDYTRVLVSKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDILTGNGVGYQEVTIF"
     gene            10857..11828
                     /locus_tag="KOU88_003676"
     CDS             10857..11828
                     /locus_tag="KOU88_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3213502.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSNVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IDTTKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTITIDDWVEDAENGFKATVTH
                     SLLTQRIVVNIIDATTKENVVTNFKIIDDNSIEVRSETRSELNVYVINGNAETHFINA
                     TVDDNRVSEMTTYSSKKIEDRFLNLEEKVNGGLSSIATSVNELITYC"
     gene            11845..>12158
                     /locus_tag="KOU88_003677"
     CDS             11845..>12158
                     /locus_tag="KOU88_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213503.1"
                     /translation="MQTEWNFGYNGSPQSVILKPGKYKFECWGSSGGINNSSWYTDAK
                     GGYSKGEITLKKQTTLYIYVGESGYASSSTANNTKSGFNGGGKGYLNQQVMGTYYSMY
                     GGG"
BASE COUNT         4845 a         1411 c         2368 g         3534 t
ORIGIN      
        1 ttaaaaactg gtaagttcat attccacaag gttggagatg aagtccatgt gttagaagat
       61 ataaatacct ttgtatcatt tacagatgag aagaatgatg atttctcaag taatcaaagt
      121 attagagtat tagaccaaat tgctaatgat attgcaacac tattcaatca taaatatcaa
      181 ggtgcagtgc caaacgacaa atctggtcgc atttcatttt ggaatgatgt agtgaagcat
      241 catgaacaac tgcaaaacat gagagcaata gaagatttca aagctgacga tgtttctgta
      301 gaacctggaa acgacaagaa aactgttgta gtgagtgatg ctgtaaaagt tattagtgct
      361 atgagtaagc tttatatgac tgtttcagtt agttaagaga ggagtgtgat aaatagatgt
      421 ctaaaaatat tactatgaat gttagagatg caataagcgg ttctaaagct gaatgttttg
      481 taacaataaa aggtaaaaga tataacttta tgcaagctat taacttagaa gctaaaatgg
      541 aaaaaaataa aagtgagatg ccaatcctag gtagcattac aaaaggaaac aaaagtacag
      601 gaagtaaatt ttcagggagt gctacctttt attataatac ttccattttt agagagttgt
      661 tatatgaata taaagaaaca ggcgaggata tttactttga tatgcaaatt actaacgaag
      721 acccaacaag ttcagtaggt cgtcaaacta taatacttga agattgtaac ctggattcag
      781 gtataattgc taaatttgac gctgatggag aatatttgga tgaggatgta gattttactt
      841 ttgagaattg gagaatagtt gagaagttca atatagcaaa tggtatggag taaaatacac
      901 atttatgatt tatggatgtg tattttttta tttataagaa taggagatga ttaaaattaa
      961 ggataaatat gagataaaag attcaatttc ttttgattat agcaataaaa gacctttgga
     1021 agaacgtgtc agcgagatgt ataaaaaggc aggaaaatat cttatagata tttcagataa
     1081 gttagcaaca gatacaattg atggttcgtc attaaagcca ataatcataa aatttgaaat
     1141 aaatgaagct ggtgttgcaa caatagaaaa acaaacaaaa tatttaatca tggaggtaga
     1201 ataatatggg agatttaaac gcttttttaa gtcaaaatgc aataaaagta gaaaatagaa
     1261 agtatgtggc aagtgaaagg tttataggtg aagatgggaa accaatagag tgggaactta
     1321 aagcaataga ttcagataga gatagacagt taagaaaaaa ttctgctatc agagttcctg
     1381 ttatagggaa aaaaggaaaa gcaacaggac aatacactag tgaaacagat tttaatactt
     1441 acactttgaa attatgtgtg gaaactatag tatttccgga tttacatgat gcagaattac
     1501 aaaatagtta tggtgtaatg ggggcagagg agttattaac aacaatgttg actcctggcg
     1561 aatatacaga cctttcaagt gaggtaggag aggtgaatgg ttttgatagg acttttgagg
     1621 ataaagtaga agaagcaaaa aactaattga aggaggcgat tatgatgcta gtgtagctca
     1681 ttattgcctt cataaattca aatggaaacc acatgaatat acagatttac cagactacga
     1741 gagggcattt gttgctgctt ctatagatat taaagtagaa gaagaaataa aagaagaaaa
     1801 aaagactgct aaagaagcta gaagaagtag aagaagataa aatataggta aaatatgtaa
     1861 gaattatatg atataataat tttagcaaga agatgtaatc tacaatttat agagtggagt
     1921 tcatgtatta aaaaattatc ctcccaacga taagaaggga ggtgaatata catggataat
     1981 tttttattta atgtgttagc tagtgtaaca gctagttaca tagtttattt gattagcaag
     2041 ttaatcaaaa aagtaaaaag ccactctacc gcaaagagtg acttaaagat tgatataaat
     2101 tttaaatatc atcgtaaaaa ataactttca gttatagaac ttcactctac cgcaaataga
     2161 ttgtagttct tcttgctttt attataccac aaattggtac agatattcaa aaataatatt
     2221 tttatgatat aataaaggca tagaaatttt gcagtgttcg attttttgaa gaaattaagg
     2281 cttaagcgtt gaaatataag gcattgagaa cgtatgataa gtgttatcat ttgcactact
     2341 gcccactcac tgcaaattta ggagagttgc atatgtgtga gcattggaaa tactaagttt
     2401 atttttgggt tttagattaa ctaagtggta tgtaaagtcc attttcgagc atgatttttt
     2461 ctataacctt gtccatttta tattaactat gtggacttaa aattaaaaat aattaaaaac
     2521 acgtacttaa aaagtaggtg tttttttatt gaaaggatgt gattataatg taaaaatttt
     2581 acttatatag tataataatc ttataaaatt gcgtaggggg taatattatg ggattgtttg
     2641 gaagtaaaga taattgttgt atttgtggag aaaaaggaaa acaaaaaata gctgatggat
     2701 ggttgtgtaa agagtgtttt aagaaatatg cagttgccac ctttactcca ggaaatactt
     2761 tatatcgtgg gttaccaact aaattagagg tcgagaaggc tattgaatca aaagatgata
     2821 aagaaaaaga gcttaaaaat tttaatccta caaaaaaaat attaaaattt atggaatttg
     2881 atgataataa taagaaattt attgttttaa atgggtttaa tagagaaaaa gtgaatttaa
     2941 atgtttataa ttacagtgat gttatagaat atgaacttct agaaaatggc gaaactgtga
     3001 ctaaaggagg gataggaaga gctttagcag ggggagcttt atttggagga gtaggtgctg
     3061 ttgttggagg agtaacagct aaaagaacaa caaaagcttt catagatagt cttaagataa
     3121 aaataacatt aaataattta agtaatccta atgtttatgt aaatctgata caattaagaa
     3181 ctaaaagtaa ttcttcaatt tacaaaatgg catattcttc tgcacaagaa atattatctg
     3241 ttttagcaat aattgtaaag gataatgaag ctgttaatat acaaaataat tctaatgatg
     3301 caatacaaca agtaaaggga ttaaaagaat tgttagactt aggagcaata acagatgaag
     3361 aatttaatac taagaaaaaa gaattgctaa atttataata tataagcact tacttaaaaa
     3421 taagtaagtg cttatattat gttaaaaaag aaaggaggtt aaaaatggca acgatacaga
     3481 catctatccg aattttcgac ggaatgacac ctgcttttag acacatgaat aatgctatga
     3541 atattgtatt aagttcattc gagcaattac aaagaacatc tagcaatgct atagatgcta
     3601 atagtattag aacagctaga gaagaactag cacgtgcaga agctggcttt gatagactag
     3661 aacaacaaat aagagaatca gataatcaac agcgaaggct taatgaggat ataaataagg
     3721 gtgcaagttc tacagataga ttagttggaa gtgcaaagaa gctagcagca acctacttag
     3781 gtataagaac gttaggaggt ctaggaaatt taagcgacca gatgacaagt actaacgcga
     3841 gacttagtat gataaatgat gggcaacaat cagatgctgg acttaataaa atgatatttc
     3901 aatcagctga aaggtcaaga gcatcttact tagatactgc acaaatagtg agtcgtatag
     3961 gcatgaacgc aggaaaggcg tttagcagta caaaagaaat tgtaggtttt gcagagcaat
     4021 taaacaaaaa atttgtaata gcaggcgcaa gtactgagga aatgaactcg gcattgttac
     4081 agctaaccca agggttgagt tctggcgtat taagaggtga ggaactgaat gctgtgtttg
     4141 agtcagcacc taacatcatc caatcgattg cagattattt ggacgtggac ataggaaaaa
     4201 taagaggaat ggcatcagag ggaatgttaa cagcagatat tgtaaaaaac tcattacttg
     4261 cagcagcaga gcagaccaat gcagagtttg aaaaaatgcc ttacacattt tctcaaattt
     4321 ggacttcaat taaaaataat gcaatcatga tatttggtgt tatacagaaa aaaattgaac
     4381 agtctatgtc tagtaaggga tttcgaacct ttatagataa ttttataaac tctttgtatg
     4441 tacttggaaa tgttgcttat aacattttta atggaattat aagtatatta gggagcccag
     4501 cttttcaaag tttttcaaac acaatgattg ttgggataag tttaatttca caagcactag
     4561 gctggataat aacacaagca ttaaaccttg ctaatatatt tgcacaaaat tggagtataa
     4621 tatctcctgt aattttgggg attgtaggag cattaacatt atacaaaaca gcagtactag
     4681 gactagcaat tgcaaattcc attgcattat tatctcaaaa atggtttgat tttcaactag
     4741 ctcaaacagc cattatgcat gacctagcca caggagcaac atggagacaa attatagcac
     4801 aatatggttt aaatgcggca ttatatgcat gtccactaac gtgggtagtt ttaggtataa
     4861 ttgcagtaat atctgctgta tttatattgg tagctgtgta taatcatttt gcaggaacaa
     4921 gcataagtgt aataagtctt gcagttggag cttggtattg gttatgtgca gtcgtttata
     4981 acgtaatttc agggatagta aatgcgataa atatttgtgt agttggaata gcaaatgctt
     5041 ttagaactgg tttatatgca gtacaatgtt tttttattga tatggctaac gcaggactca
     5101 aggcaggtgt taatttagac aaagcatttg ataaatttgc tacaaatcta gcaaatggaa
     5161 ttataaaggc tgttaatata gctgtaaaag gattaaattg gttagtggaa cagattaata
     5221 aaattccagg aattaattta ccacaaatga aagaatttca aaaagtaaat actgtaattg
     5281 gtacaaaaac aacatttaaa cccattcaaa aaccgcctga gcctaaagca tggaaaccag
     5341 aattagtaga gtacaaaaat ttaaagtcag aatttataaa aggatatgac gtaggacatc
     5401 aattacaaaa caaattgaaa gatacttttg atatcagtaa aatagcagaa gatgcaaaga
     5461 aaaaattagg attagatgac ctttgggata agaagtatgg attaggaaat ggatttggtt
     5521 cagctggatt aaattcacct ttgggcgacg cagcaaaagg agcaaaggac acagcaggaa
     5581 acactgcaaa aatggcaaag actatggata aaagtcaaga agatttaaaa tatcttagag
     5641 atattgcaga gcaagaaaca ataaaccgat ttacaggagt caacattaaa attgatatga
     5701 acaatacaaa taacataagc aaagatgcag atgtggatgg tatagtaaac gtcttaacag
     5761 aaaaattaaa tgatgccatg gttgtttcag ccgaaggaat agtttaggaa ggagggatat
     5821 aaatggctta tgatttttac ctagatggag tacaactacc aatcgcacca cccaagcttg
     5881 aagtcaaagt gacaaataaa aacaagacag ttgatttaat aaatgttgga gaagtaaaca
     5941 tactaaaaaa agaagggcta tctgaaataa gttttgaagc agaatttaca cataataaac
     6001 taccatttta tcgagggact tttaaagatg ttcaattctt tttaagtaag ctagaattac
     6061 taaaaactga ttgtaagcca tttcaattta ttgtctcgag ggaaatgggt ggaaaagtac
     6121 tatttaacac taatataaaa gtatctcttg aagagtatgc tatttcagaa gatgcagaaa
     6181 atggctcaga tacaaaagtt gcaataaagt taaagcaata tagagattac tcaactaaaa
     6241 agttagttat tgcccctcct aaaaatgaga ctggtagacc taatgtaaag atagagccaa
     6301 aacgagttga ttcagtcaat gccacaaaca ctaaaactaa aactaaaaca tatacagtaa
     6361 aagcagggga tagcctttgg tcaatttgtc agaaacaact tggtaatggt tcactatata
     6421 agaaagtata cgaactaaat aaatcaatga tggataaagc taacaagggt aaaaaagtac
     6481 ctaaatatac catctacaaa gggcaggtgt taaaacttgg atgatgaatt agtattagca
     6541 aatgacagag atgtaagatt agtaatagct cattgggaag atttctatga acctgctgtc
     6601 cttgataaca taacatggga aatagaaaga agaggttcgc cttctaagtt agagtttact
     6661 atagtaatgg atgatatatt agagttttgt gaaggtaatt ctgtaaggct atattacaag
     6721 ggaataggca tattttatgg atatatattt caaaagaaaa gagataaaga aaatcacata
     6781 aaaattgttg cttacgacca gttgagatat tttaagaata aagatactta tgtatatagt
     6841 aataaaacag caagtgaact tgtaaagatg ttggctaaag attttaattt aaaatacaat
     6901 gtcatagaag atacaaaata taaaatatcg agagttgaag aaaataaaac actctttgat
     6961 atggttttaa ctgcacttga tgatacttta agagagaaaa aggaaatgta tgtactatat
     7021 gatgactttg gaagaataac attaaagaat gttgcatcaa tgaaattaga tactgttatg
     7081 aataatgatg taatagaaga ttttgactat aactcttcta ttgatagtga tacttacaca
     7141 aagataaaat tagtaagaga taatgaagaa acaagtaaaa gagatgtcta tatcgcccaa
     7201 gattcagctc acataaggag ttggggtgtt ctacaactat ttgagacagt agataaaaat
     7261 atgagtgaag cagaaataaa acaaaagtgt gatatacttc taaaattata taacaggaaa
     7321 actaagacat taagtttaaa aaatgtgtta ggagatatta gagtaagagc aggttgttta
     7381 gtacctgttt ttttgtcgtt aggagatatt gatttacaaa attatatgtt agttgagaaa
     7441 gtaaaacata catttgaaaa taacagtcat tttatggacc taactttggt tgatggagac
     7501 gaatttgctt cttattcttc atcaagttat agtagtggaa atactaataa taaaaatgag
     7561 aaacaaaatg gtcctgcaca aagtactaca agtaaagaag atactgatat ggctaataag
     7621 attaataaac tacttaaagg taaattatca aatacaggaa atatatttgt taaatattca
     7681 aatgcttata aagttaatcc agcactcatg gctgctatat ctatgcacga atcagctaga
     7741 gggacttcaa atattgcaaa tactaaaaat aatttctttg gaatgaaaaa aaatggagat
     7801 tacatgagtt tttctagtgt agacgaagga ataaaaagag gtataagtaa tttatcaaga
     7861 aactatatcc atataggacg aaaaacttta gaaagcatca gaaataaata ttcttctagt
     7921 tcagacaaag aatgggtaaa atgtgtaggt gcattttata agcaaataac aggaagtact
     7981 tataattcta atagtgcagg cacaggagtt ggaagtaatg aagaagcaga aaagaattta
     8041 aaagatttaa cttatcaagt tcaaaacaat aattctaata catcaacaaa caataataat
     8101 aaagtaagta aagttattca agaagcaaaa aatcaacttg gcaagcctta caaatggggt
     8161 ggtaatggtc caaagagttt tgactgtagt ggtcttatgg tgtgggcatt taaaagaggt
     8221 gcaggaataa atctcaaaag agtttcagca gaccaatcaa aagatagtag aggaaaacta
     8281 ttatgtaaca taaatgatgt aaaagctggt gatttagtat tctttgcata caacaaagga
     8341 aaaggaaatg tacatcatgt tggactatat ataggaaatg accaatatat tcatgctcca
     8401 caaactggtg acgtagtaaa aataagtagt ttaagtggta gacaaaagaa aaagcatgat
     8461 tttgcaagag ctagaagatt cttttaagtg aggtgataaa gtgtcacaag aattattgca
     8521 aataattaag aaggctgcaa tggatgcagt agaaacaagc aatccaatgc aaattgcatt
     8581 tggaactata gaaagtgtta atcctttgat agttaagata gaacaaaaag catcttttga
     8641 agaatttttt ctaatacaaa cagagacttt taaaagatat acagataaaa aaatagggga
     8701 taaattagtc ttaattagga tgcaaggagg acagcaatat ttgattttag ataggatgtg
     8761 atgaggtgtt accaagcgat aatttggatt atgacattga agatgtatca ataattaatt
     8821 ttgatgtaag gcaagaacca agtaagacct ttaaattaaa tatagaaaaa tctaagatag
     8881 atggtatttg tgatgatgtt gaagcattaa aacagaccat ctttttaatt ttaaatactg
     8941 aaaggtatga gcacctcatt tattcttgga attatggagt cgagttgaac gaccttattg
     9001 gagaacctat atcctttgta atccccgaac ttgaaagacg aatcaaagaa gcactaattc
     9061 aagatgatag ggttgaaaat gtagataatt ttgaatttca aaatgtaaaa ggaaaagtac
     9121 attgtaagtt cacagttcac agtaaatatg gaaatataaa agcagagaag gtggtgagtg
     9181 tataattgtt tgagttaatg acatttgaaa acataattaa aagaatgtta gatagtgtac
     9241 cagatacctt tgataaaaga gaaggttcta taatatataa cgccttggca ccagtagcta
     9301 tagaacttac agaaacatac attgccatgg atgaattatt agaccaaacc tttgtagata
     9361 ctgctagtta ttactattta gagaaaagat gcaaagagcg aggaatcaca cctcttgaag
     9421 ccactaatac aattgcaaaa ggagttttta atatagatat tcctattgat tcacgtttta
     9481 acctaggaga atataattac attgcaactg aaaggattgg tgaaggaata tataagatga
     9541 aatgtgagac tgctggacct atttttgagt tggggcaact aatacctatc gaatatgtag
     9601 acaaattaga aacagcagaa ctgacagaaa tactgataaa tggagaagat gaagaatcag
     9661 aggacagtct aagacaaaga tattatgata gtttaaattc tcaatctttt gggggtaata
     9721 tacaaaacta taaggatgaa gttaataaat tgcctgacgt tgggggagtt aaagtatatc
     9781 cagtttggaa cggtggagga actgttaagt tagtaataat taattctaat ttcaaagtac
     9841 catcagagga tttagttaat ttagtgcaag aagaaattga cccaattgga catcaaggac
     9901 aaggcttagg attagcacca ataggtcata gagtcacagt tgaaggagtt acaagtacaa
     9961 ctataaatat atcagcagag ataacatata aaaacagcta cacttgggag aatataaaat
    10021 caattgcaga agaagcagtt gatgactatt taaatgaact taacatgagt tgggaagatg
    10081 aagaaaattt aatagtccgt atatctcaga tagaaactcg tttgttaagt atagatggag
    10141 tgttagatat tacaaacaca atgataaatg atgttaaatc taatctaaca atagatagta
    10201 acagcatagt aacaagaggt gaggtaattg gataaaaaaa ttaatctaat aaattactta
    10261 ccacaagttt tgcaagataa agaagagtat ataaaagtat ttaatgcaga aaacaaagaa
    10321 ataaaaacat tacatgataa attagatgat gtcttaaatg accagttctt agaagattta
    10381 actccaagtg gtgtgaaaag atgggaaaaa ataatgtcta taactcccaa atcaaatgaa
    10441 actttagagg atagaaggtt taggattttt agtagatata taagtaaatt accctattca
    10501 gagagatttt taagaaattg gttagacaat attgttggag aaggaaacta tgagttaact
    10561 attaacaatt ctacttataa catacattta gagagtgatg ctagaaatca agattggttt
    10621 gaagaagttc attcttttgt aagtagcatc aaaccttgca acatgagtct tgattatact
    10681 agagtgttag ttagtaaaga taattacatg aattttggaa taacaaccct aatgggtcaa
    10741 gaaataacta tatacccttg gagtccgcca gatatagaaa cttatggaga aattgatata
    10801 ctaacaggaa atggagttgg atatcaagag gtaacaatat tttaggaggt gatatattgg
    10861 ctatagataa aagttattac actataatta cagatgtagg aaaagcaaag atagcaaatg
    10921 caagtgttac aggcaataaa gtcggatttg taaaaattca acttggtgat ggtggaggta
    10981 gtgaatatac tccaacagaa agccaaacag ctctaaaaaa tgtagtttgg gaaggtaata
    11041 ttgggaatac aactacagat gaaacagcac caaattgtat aatactagag agtcttatac
    11101 caagtaatgt aggcggattt atgataagag aaatagggta tttagatgat gaaaataatc
    11161 taattgccat ttctaaatat aaagaatgtt ataaaccttc tatagaacaa ggggcagtag
    11221 tagacatgaa ggttaaaact gtgctgattg tatctaatgt aaataatata gaacttaaaa
    11281 ttgacccaac aataatcttt gcaacactca aagatataca agacttagaa actaaaattg
    11341 atacaactaa aacagagtta aatactagaa ttgacacaga aaatgagaaa caaaatatta
    11401 aaattgacca attaatcgca ggtggttcaa atgtggcatc tactcaaaca ataacaattg
    11461 acgattgggt tgaggatgca gaaaatggat tcaaagcaac tgtaacacat agtttgttaa
    11521 cacagagaat agttgtaaat attatagatg ctactacaaa agaaaatgta gttacaaact
    11581 ttaaaattat agatgataat tctatagaag ttagaagtga aacaaggtca gaattaaacg
    11641 tttatgtgat aaatggaaat gcagaaactc attttattaa tgcgactgtg gatgacaaca
    11701 gagtgtctga aatgactact tattcgtcta agaaaatcga agatagattt cttaatttag
    11761 aagaaaaagt aaatggtggt ttatctagta ttgcaacaag tgtaaatgag ttgataactt
    11821 attgttagag aggagagtga gaaaatgcag acagaatgga actttgggta caatggttcg
    11881 ccacaaagtg ttatattgaa acctggcaaa tataaatttg aatgctgggg ttcttctgga
    11941 ggtatcaaca attcttcttg gtatactgat gctaaaggtg gatattccaa gggtgaaatt
    12001 acattaaaaa aacaaactac attatatatt tatgtcggcg aaagtggtta tgcttcttca
    12061 tctacagcta ataacactaa aagtggtttt aatggtggtg gcaaaggtta tttaaatcaa
    12121 caggttatgg gtacttatta ttctatgtat ggtggtgg
//
LOCUS       DAFAZV010000078        11727 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFAZV010000078 DAFAZV010000000
VERSION     DAFAZV010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11727
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.081"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            483..1376
                     /locus_tag="KOU88_003678"
     CDS             483..1376
                     /locus_tag="KOU88_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfide/dihydroorotate dehydrogenase-like
                     FAD/NAD-binding protein"
                     /protein_id="HBK3213504.1"
                     /translation="MSNKIVSKRQLTDSIYLMEIEAPRVAKSSQPGQFIIIKNDEKGE
                     RIPLTIADYDREKGTVTIVFQTVGASTKKLAMFEENDFVMDFVGPLGQASEFIHEDIE
                     ELRNKKILFVAGGVGSAPVYPQVKWFKEHGLDVDVIIGARTKELIILEDDMKKVAKNV
                     YVSTDDGTYGFNGRVTDLLKDLVDNQGKKYDQAIVIGPMIMMKFMCQLTKELNIPTIV
                     SLNTIMIDGTGMCGGCRVSVGNETKFACVDGPEFDGHLVDFDQAMRRQSMYKTQEGRA
                     MLKLEEGDSHHHSNCGCGGNK"
     gene            1376..2770
                     /gene="gltA"
                     /locus_tag="KOU88_003679"
     CDS             1376..2770
                     /gene="gltA"
                     /locus_tag="KOU88_003679"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent glutamate synthase"
                     /protein_id="HBK3213505.1"
                     /translation="MDAKKVKVPVREQEPAVRATNFDEVCLGYNKEEAMAEANRCLAC
                     KKPKCVGGCPVGIDIPGFITKIKEDDIEGAAKVIAKSSSLPAVCGRVCPQESQCEGVC
                     ILGIKSDAVSIGKLERFVADWSKENDINLSDTEPKKNQKVAVIGSGPAGLACAGDLAK
                     KGYDVTIFEAMHEPGGVLTYGIPEFRLPKQAVVQPEIDNIRKLGVKIETNVIVGKTIT
                     VDELIEDEGFEAIFIGSGAGLPMFMNIPGENANGVFSANEFLTRVNLMKAYRDDYDTP
                     ISSGKKVAVVGGGNVAMDAARTALRLGSESYIVYRRSEKELPARAEEVHHAKEEGIVF
                     NTLTNPKEILVDENGYVKGMVCIRMELGEPDDSGRRRPIEIEGSEFVLDVDTVIMSLG
                     TSPNPLISSTTKSLDINKKRCLITDENGQTSKEGVFAGGDAVTGAATVISAMGAGKTA
                     AASIDEYLKAKVNA"
     gene            3136..5355
                     /locus_tag="KOU88_003680"
     CDS             3136..5355
                     /locus_tag="KOU88_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3213506.1"
                     /translation="MKKREKVFDGLVFKHILILLILLVLIDLTSTIIYASNSMEITSR
                     NMIEASKRELENYLEVNISLLKALSQDDRFSNGETSLIEKGKLLSPYQKEYNLFMIGI
                     TDTKGNASSTYRENVNSIKDKPSFEKAIKTKQVVVSDIEVSNVTGDKVFIIYVPIVKN
                     NEMIGTIFASFYFQDVNNLISRSNFDDSIKFLMIDKDYTIISHPNKKYVNDKSKMLDL
                     EGNIIGTTKSEILKNINKKCQGDFLSWDNWRLYNVKYTNVKWTNWTLVSKCNIFKNFK
                     NLIVNFMIKLYFYIVIFMILWKLSNAKLIEQLKKLAYYDSLSGIKNKEKFRKDSMYIL
                     KNYYQDNFYLVQLDVNKFKYINEMFGYAEGNKILIHISQVLNNNTNKYEICARMDNDH
                     FILLIACNTEDELLNRLSKINKEICNLNTTNSSKYKIVMSSGIYKITKKDDIKKIDLL
                     IDRANIAAKSKKEKYEHSYSFFNEDTRNRLYKEKRLEDNMNKALEKGEFIVYYQPKYS
                     LDDVNEIEGAEALIRWNSPEFGFISPIDFVPLFEKNGFIVNIDMFVFEEVCKTLNKWI
                     NKGYTPVPISVNMSRVHLYRDNFIENITDLISKYNISPEFIELELTESVVFDNLNILI
                     DIMKKIKEIGFLISMDDFGSGYSSLNLLKDLSFDILKLDRGFLIETTDTKRGKIIISK
                     IVEMAKAIDIKVICEGVETYEQVEFLKEIGCDKVQGYLFAKPMVLDEFEKHLNFKFD"
     gene            5502..6248
                     /locus_tag="KOU88_003681"
     CDS             5502..6248
                     /locus_tag="KOU88_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014466367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213507.1"
                     /translation="MNILSIRNISKTYCGNIPFKALDKVSLNIEKGEFVSVMGPSGSG
                     KSTLLNIISTVDRQSEGEVVLDGYDVSKLKGEKLAEFRRKQLGFVFQDFNLIDTLTVG
                     ENIMLPLTLEGASIKDMNIQTKSISKFLGIDKILDRKTYEISGGQAQRCAIARAIINK
                     PAILLADEPTGNLDSKSTDDVLKLFTRINKEQKVTTLMVTHEAYSASYSDRVIFIKDG
                     CIYTEIKKSESSNSFYSDILAVLSQIGGVR"
     gene            6248..8128
                     /locus_tag="KOU88_003682"
     CDS             6248..8128
                     /locus_tag="KOU88_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213508.1"
                     /translation="MDFRKFAYNNIVRNFRAYLAYFLSSVFSIMIFFVFAVSMFHPII
                     TKSGMQSGSTAFMALMTSELIIFGFSLLFILYSLGNFLKYRLKDFGVLMIIGMSNRQL
                     KKLILIENLIIGFLAVMLGILLGLSISKLFLLYLSKLFYMNLTEFYFPVKAMLLTIVS
                     FMILFLITGPMSLKLLSKKSILELLVGTKKPKKEIKSSKLFGIIGVICLILGYAMILF
                     GNKLKINGGMYTTALLITLGIFLFFSQFTILILKYLKNKEKFYKNKVNMLLISNLIYK
                     LKDNTRLLFLITILLSATLVAFTTTSTLVSSQGEASKNNFPMVYSYFSEHNNEKEYEE
                     LQQIREAIKGYDYKELSFPVLKYNREVLLSVKNYNKLSKELGLDKISSKLEKYEGIII
                     PSSNSQEHINSLKQLKNYSIKNLNIEVKKSKNKIIFPTGLFSKVVVISDDLYNEVKGE
                     FSKINFHGFDYKNWQSSAKITENLKEKHFNLDREYNRSYFLTLPDMYLVELQQSKILQ
                     FMGVFIGVILFIAVFSFLYFRLYTDEIEDNVKYKKLSKIGLSFKNMNKIVSIEIGTLF
                     FIPYFIAIINSIISLLFLNQVLNNSFKLENLGILLLISSIYSLYFYLLKKIYTRKVWF
                     FD"
     gene            8247..9638
                     /locus_tag="KOU88_003683"
     CDS             8247..9638
                     /locus_tag="KOU88_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3213509.1"
                     /translation="MENQQLLGTERISKLLLKYSIPAIIGMLVNSLYNVVDRIFIGNI
                     PGVGPLAITGLGVTMPIMTIILAFGMLIGIGTTTTISIKLGQGKVEEARKLIGNAMTL
                     SVITGIIIMILGILFANKILTLFGASENTLIYAKSYINIILLGTVVNLLSFSLNHSIR
                     ADGSPKISAGIMIVGCLTNIVLDWILIFGFNLGIQGAAIATVTSQALTAILTIGYYIS
                     GKSNLRFSKSNLKLDKKLIKAVFAIGMSPFAMQLAASLVQVISNIALKTHGGDLAIGA
                     MATISSIAMVFLMPIFGINQGAQPIIGFNYGAEKYDRVKKAYLGSLVVATIILCMGMV
                     VVMLFPEAIIGIFNKDPELMNISVNGLRIYLLMLPIVGLSVTGTNFIQSIGKAKMAML
                     LSLLRQVILLIPAVLILPTFLGLQGVWTAQPVSDFIATVITGIVVFRELKRYTPKTEK
                     LNENERLNEITTE"
     gene            9745..10785
                     /locus_tag="KOU88_003684"
     CDS             9745..10785
                     /locus_tag="KOU88_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBK3213510.1"
                     /translation="MEFTKKSKLKNMYVNMNVARMLSKINEYKGRQLLYKKQPKEILE
                     NLEKKSLVDCSESTYIGNQRDSSNFNLEKLISNEVTPRSREELSIVEYRDVVKTINSA
                     YESIPISSQTILELHGYLYKFSSTRGGSYKSDNDFIEHNLKPSEFISTDSSVNKVEKA
                     VEEICEAYNTLIEEDEIDILILISAFVLDFILIHPFKEGNIKMARVLILLLLNKNGYE
                     VGRYISLGKIFDDSSYEYYSNLNYLKASIGSEKADMNAWIEYFLETILTAYEKLDDSL
                     NISDKKRQTKTSRIEKIINSTLGYFTKEDIRDLCPDIPEPTINRVFNNLRKQDKIEVV
                     ARGRSAKWKKKY"
     gene            11274..>11727
                     /locus_tag="KOU88_003685"
     CDS             11274..>11727
                     /locus_tag="KOU88_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBK3213511.1"
                     /translation="MKKKLLYINVNSKPEDLSSSKTVARKFINKFMEKNKDFEVEEID
                     LYKEHIPRLEYQYFEKRNSIVSEENAKNLDDKDRKELTKIRNLCDQFVSASVYVIAAP
                     MWSLSFPAPLKEYIDCIIQDGKTISFEGNDKPQGILNDIDRSMVYIQSS"
BASE COUNT         4666 a         1133 c         2051 g         3877 t
ORIGIN      
        1 aatgaatatt gaaaatttta gatatataat aaaataagag tatattttat acaatatgaa
       61 agctggtatt gcaatagatt aaagccttat acacgtttag tttttaaaga aattagtgtt
      121 attatgaaaa cctaagttaa tttattaaat aaataattga ataaaaaaat tttattatgt
      181 atttataaaa tttttgttac aaatttggca taatatagta tactttaagt gtgtattagg
      241 ttaaatctat aacaaattag acgtatgata tagacttagt gtttattggc atttacaaga
      301 aatttgttaa tatcaactat ttgtagtttg ggcagttata attattatag gggggatgtc
      361 caatacaaaa caatcaacca agaactaata ttatattata aagagttata gttttgtgtg
      421 tttatgtttt taattaaatt taaagtggga aaaatatatt tgttagaatg gagaatagcg
      481 agatgagtaa taaaatagtt agtaagagac aattaacaga tagtatttat ttaatggaaa
      541 tagaggcacc tagagttgca aaatcttctc aaccaggtca atttataata attaaaaatg
      601 atgaaaaagg agagaggatt cctcttacaa tagctgacta tgatagagaa aaaggaacag
      661 taactattgt attccaaaca gttggtgctt caactaaaaa gttagcaatg tttgaagaaa
      721 acgattttgt aatggatttt gtagggccat taggacaagc aagtgaattt atacatgaag
      781 atatagaaga attaagaaat aaaaagatat tatttgtagc tggtggagtt ggttctgctc
      841 cagtttatcc acaagttaaa tggtttaaag agcatggatt agatgtagat gtaataattg
      901 gtgcaagaac taaagaatta attatattag aagatgatat gaaaaaagta gctaaaaatg
      961 tatatgtatc aacagatgat ggtacatatg gatttaatgg aagagttaca gacctattaa
     1021 aagatttagt tgataatcaa ggtaaaaaat acgaccaagc aatagtaatt ggaccaatga
     1081 taatgatgaa atttatgtgc caattaacta aagaactaaa tatacctact atagtaagtt
     1141 taaatacaat aatgatagat ggaacaggta tgtgtggtgg ttgtagagtt agtgttggaa
     1201 atgaaactaa gtttgcatgt gtagatggtc ctgaatttga tggtcattta gttgattttg
     1261 atcaagcaat gagaagacag tctatgtaca agactcaaga gggaagagct atgctaaaac
     1321 ttgaagaagg cgatagtcat catcatagta attgtggatg tggaggtaac aaataatgga
     1381 tgctaaaaaa gtaaaagtac cagttagaga acaagaacct gctgtgagag caacaaattt
     1441 tgatgaagta tgcttagggt ataataaaga agaagctatg gcagaagcta atagatgttt
     1501 agcttgtaaa aaaccaaaat gtgtgggtgg atgtccagta ggaatcgaca taccagggtt
     1561 tataacaaaa attaaagaag atgatataga aggtgctgct aaagtaatag ctaagagcag
     1621 ttcattacca gctgtttgtg gtagagtatg cccacaagaa agtcaatgtg aaggtgtatg
     1681 tatacttgga ataaaatcag atgctgtatc aataggtaaa ttagaaagat ttgtagcaga
     1741 ttggtcaaaa gaaaatgaca taaatttatc tgatacagag cctaagaaaa atcaaaaagt
     1801 agcagtaata ggaagtggtc cagcaggtct agcttgtgct ggtgatttag ctaaaaaagg
     1861 ctatgatgta acaatctttg aagcaatgca tgagccaggt ggagttttaa cttacggaat
     1921 acctgagttt agacttccaa aacaagctgt tgttcaacct gaaatagaca atataagaaa
     1981 attaggtgta aaaatagaaa ctaatgtaat tgttggtaaa acaattacag tagatgaact
     2041 tatagaagat gaaggatttg aagctatatt cataggttca ggagctggtc ttccaatgtt
     2101 tatgaatata ccaggggaaa atgcaaatgg agtattttct gcaaatgagt ttttaactag
     2161 agtaaactta atgaaggctt atagagatga ttatgataca cctattagtt ctggtaaaaa
     2221 agttgctgta gtaggtggtg gaaatgttgc tatggacgct gctagaactg cattaagatt
     2281 aggttcagaa tcatatatag tttatagaag aagtgaaaaa gagcttccag caagagctga
     2341 agaagttcat catgcaaaag aagaaggcat tgtatttaat acattaacaa atcctaagga
     2401 aattttagta gatgaaaatg gatatgttaa aggtatggtt tgtataagaa tggaattagg
     2461 agagccagat gattctggaa gaagaagacc tatagaaata gaaggttctg aatttgtact
     2521 tgatgtagac acagttataa tgtcacttgg aacaagccca aatccactaa tatcttctac
     2581 aacaaagagt cttgatataa ataagaagag atgcttaata acagatgaaa atggtcagac
     2641 ttctaaagag ggtgtatttg caggtggaga tgctgttact ggagcagcaa cagtaatatc
     2701 tgcaatgggt gctggtaaaa cagcagcagc atcaatagat gaatatttaa aagcaaaagt
     2761 taatgcttaa tttgtacatt aaagagaggg tgtctcaaaa tgaacttttt agttcatgag
     2821 gcactctttt tgtacaaaat caaatatgtt ttaatcattt caacaatgaa aatttcattc
     2881 ctgtagaaag tctaactttt aggtcttagt acaatctcta ttttgatgta gccacttttt
     2941 tagatggttt aataatttat cagttattat tgtaatattt gatactaagt aacataactt
     3001 tgtctaacta tgataaaata gttatacaat aaaggtcttg taaggagtga ataatgtgtg
     3061 gctaataaaa tcagatttgt caaatctaac attaaataat agaaaaataa attgtgtaat
     3121 taatggtatt ttaatatgaa aaaaagagaa aaagtatttg atgggctagt ttttaagcat
     3181 atattaatct tattaatact attagttttg attgatttaa caagtaccat catatatgca
     3241 agtaactcta tggaaattac ttctagaaat atgattgagg catcaaaaag agaacttgaa
     3301 aactatttag aagtaaacat atctttatta aaagctctta gtcaagatga tagattttct
     3361 aatggtgaaa catcactaat tgaaaaggga aaattattaa gtccatatca aaaggaatat
     3421 aatcttttta tgattggtat aacagataca aaaggaaatg cttcaagtac atatagggaa
     3481 aatgttaact caataaaaga taagcctagt tttgagaaag caattaaaac aaagcaagta
     3541 gtagtttcag atattgaagt cagtaatgta acaggtgaca aagtatttat catatatgta
     3601 ccaattgtaa aaaataatga gatgattggg accatttttg cttcttttta ttttcaagat
     3661 gtaaataatt taataagtag aagcaatttt gatgattcta ttaaatttct aatgatagat
     3721 aaagattata ctattatttc tcatccaaac aaaaaatatg taaatgataa aagtaagatg
     3781 cttgatttag aagggaatat tataggaacc actaaaagtg aaatcttaaa aaatataaat
     3841 aaaaaatgtc aaggtgattt tttatcttgg gataattgga gattatataa tgtaaaatat
     3901 acgaacgtaa agtggactaa ttggacttta gtatcaaaat gtaatatatt taagaacttt
     3961 aaaaatctaa tagttaattt tatgataaag ttgtattttt atatagtaat atttatgata
     4021 ttgtggaaat taagtaatgc taaattaata gaacaactta aaaaattggc ttattatgat
     4081 tctttaagtg gaataaaaaa taaagaaaag tttagaaaag attctatgta tattttaaag
     4141 aattattatc aagataattt ttacttagta caattggatg tcaataaatt taaatatata
     4201 aatgagatgt ttggatatgc tgaagggaat aagatattaa ttcatatatc acaggtttta
     4261 aataataata caaataaata tgaaatttgt gctaggatgg ataatgacca ttttatattg
     4321 ttgattgctt gtaacactga agatgaactt ttaaatagat tatctaaaat aaataaagaa
     4381 atttgtaact taaatactac taactcatct aagtataaaa ttgttatgtc aagtggaata
     4441 tataagatta ctaaaaagga tgatattaaa aagattgact tgttaattga tagagcaaat
     4501 attgcagcaa aaagtaaaaa ggaaaaatat gaacattcat attcattttt taatgaagat
     4561 acaagaaatc gattgtacaa ggaaaaacga ttggaagata atatgaataa agctttagaa
     4621 aaaggtgaat ttatagtata ttatcaacct aagtatagtt tagatgatgt aaatgaaatt
     4681 gaaggagcag aagccttgat aagatggaat agtccagaat ttgggtttat ttcacctata
     4741 gattttgtac ctttatttga aaagaatggt tttattgtaa atattgatat gttcgtgttt
     4801 gaagaagtat gcaaaacatt aaacaagtgg ataaataaag ggtatactcc tgtaccaatc
     4861 tctgtaaata tgtctagagt tcatttatat agggataact ttatagaaaa tataactgat
     4921 ttgataagta aatacaatat atctcctgag tttattgaac ttgaactaac agaaagtgtt
     4981 gtgtttgata atttaaatat attgattgat ataatgaaaa agattaaaga gataggattc
     5041 cttatatcaa tggatgattt tggttcggga tattcatctt taaatctgtt aaaagacctt
     5101 tcttttgata ttttaaaatt agatagagga tttttaatcg aaacaacaga tacaaaacgt
     5161 ggaaaaatta ttatttctaa gattgtggaa atggcaaaag cgattgatat taaagtaatc
     5221 tgtgagggcg tagaaactta tgaacaagta gagttcttga aagagatagg ttgtgataag
     5281 gttcaaggat acttatttgc taaacctatg gtattagatg aatttgaaaa acacttaaac
     5341 tttaaatttg attaatcatt aataattatt agactataag ataccctaac aacttactta
     5401 caaatatgta agttaattgt tagggtattt ttatggttaa agtagcatat tcacgatatt
     5461 atggtattgt agtaaaaata aaaaattatg gagaatataa aatgaacata ttgagtatta
     5521 gaaatatatc aaaaacatat tgtggaaata ttccatttaa agcattagat aaggttagtc
     5581 taaatataga aaagggagaa tttgtgtctg ttatgggacc atctggaagt ggtaaatcta
     5641 ctcttttaaa tataatatct acagttgata gacagagtga aggtgaggtt gtattagatg
     5701 gatatgatgt aagtaaattg aaaggagaaa aacttgctga atttagaagg aaacaacttg
     5761 gttttgtatt tcaggatttt aatttgattg acactttaac tgttggcgaa aatattatgt
     5821 tgccacttac actagagggg gcaagtatca aagatatgaa tatacaaact aaaagtatat
     5881 ctaaattttt aggaatagat aaaattttag atagaaaaac ctatgaaatt tcaggaggtc
     5941 aagctcaaag gtgtgctatt gctagagcta ttataaataa acctgccata cttcttgcag
     6001 atgagccaac tggaaatctt gattcaaaat ctactgatga tgttttgaaa ttatttacta
     6061 ggataaacaa agaacaaaag gtaacaacac ttatggtaac tcatgaagca tatagtgcaa
     6121 gttattcaga tagagtaatt tttataaaag atggttgtat atatacagaa ataaaaaaat
     6181 ctgaaagcag taattctttc tattctgata tactagctgt tttgtctcaa ataggaggtg
     6241 taagatagtg gattttagaa agtttgctta taataatata gttagaaatt tcagggcata
     6301 tttagcatat tttttaagtt ctgttttttc tataatgata ttttttgttt ttgcagtgtc
     6361 tatgttccat ccaattataa caaaatctgg aatgcagagt ggttctactg catttatggc
     6421 tcttatgact tcagaattaa taatattcgg ttttagtcta ctttttatat tgtactcttt
     6481 aggaaatttc ttaaaatata gattgaaaga ttttggagta ttgatgataa ttggaatgag
     6541 taacagacaa ctgaaaaaat tgatattaat tgaaaatttg ataataggat ttttagcagt
     6601 gatgttagga atattacttg gtttatcaat ttcaaaattg tttttattgt atttaagcaa
     6661 actgttttat atgaatttaa ctgaatttta ttttccagta aaagcaatgc tattgactat
     6721 tgtatcattt atgattttat ttttgataac aggaccaatg agcttaaaat tattgagtaa
     6781 aaagagcatt ttagagcttt tagtaggtac aaaaaagcct aaaaaagaga taaaatcttc
     6841 aaagctattt ggaataattg gtgtaatatg tcttatatta ggatatgcta tgatactatt
     6901 tggcaataag ttaaaaataa atggaggtat gtatacaaca gcactattaa ttactttggg
     6961 gatattttta tttttttctc aatttactat tttgatatta aagtatttaa aaaataaaga
     7021 aaaattttat aagaacaaag taaatatgtt acttataagt aatttgatat ataaattaaa
     7081 ggataataca cgattgttat ttttaataac aatactttta tcggctactt tagtagcatt
     7141 tacaacaact tcaacacttg taagttctca aggagaagct tctaaaaata atttcccaat
     7201 ggtttactca tatttttcag agcataataa tgaaaaagaa tatgaagaac tacaacaaat
     7261 tagagaagca atcaaaggat atgattataa ggagttaagt tttcctgtac ttaaatataa
     7321 tagggaagtc ttactaagtg taaagaatta taacaaatta tcaaaggaat tgggattaga
     7381 taaaattagt tcaaagttag aaaaatatga agggattata attcctagta gcaattcaca
     7441 agaacatata aattctttaa aacaattaaa aaattatagt ataaaaaatt taaatataga
     7501 agtaaaaaaa tcaaaaaata aaataatttt tcctacagga ctgtttagta aagttgtagt
     7561 tataagtgat gacttataca atgaagtaaa aggtgaattt tcaaaaatta attttcatgg
     7621 atttgattat aaaaactggc aaagcagtgc aaagataact gaaaatttaa aagaaaaaca
     7681 ttttaatttg gatagagaat ataacaggtc atatttttta acattaccag atatgtattt
     7741 agtagagtta caacaaagta aaattcttca atttatgggt gtttttatag gagtgatatt
     7801 atttatagca gtttttagtt ttttatactt cagattatat acagacgaga tagaagataa
     7861 tgtaaagtac aaaaaactat caaaaatagg tctatctttt aaaaatatga ataagattgt
     7921 tagtatagag ataggtacat tgttttttat accgtatttt atagcaatta taaatagcat
     7981 aatttcttta ctgtttttaa atcaagtatt aaataatagt tttaagttag aaaatttggg
     8041 tatattacta ctgatatcat ctatatattc actttatttt tacttattaa aaaaaattta
     8101 tactagaaaa gtttggtttt ttgattaaag tggtatataa tagatatata aattaatatt
     8161 taaaaagtag ttaatattag gggagggcat ttgcacctcc cttgtaatat gtggaaaatt
     8221 gaatattaga agaaggagga gacttgatgg aaaatcaaca attattagga acagaacgaa
     8281 ttagtaaatt actactaaaa tattctatac cagctataat aggtatgttg gtaaatagtt
     8341 tatataatgt agtagataga atttttattg gaaatatacc aggggttgga ccacttgcaa
     8401 taacaggtct tggtgtaaca atgccaataa tgacaataat acttgcattt gggatgttga
     8461 taggtatagg aactactact accatatcaa taaaacttgg gcaaggtaaa gtagaagagg
     8521 caagaaaact tataggaaat gcaatgacgt tatctgtaat aacaggaatt atcataatga
     8581 tacttggaat attatttgca aataaaatac ttacattgtt tggagcaagt gaaaatactt
     8641 taatatatgc aaaatcatat atcaatatta tattattagg tacagtagta aatcttcttt
     8701 ccttttcttt aaaccactca ataagagctg atggtagtcc taaaatttca gcaggaataa
     8761 tgatagtagg atgtttaact aatatagttt tagactggat attaatattt ggattcaatt
     8821 tgggaataca aggagctgca attgctacag taacttctca ggctcttaca gctattttaa
     8881 ctatagggta ttatataagt ggaaaatcaa acttacgatt cagtaaatct aatctaaaat
     8941 tagataaaaa gctaataaaa gcagtgtttg caataggtat gtcgccattt gctatgcaac
     9001 ttgcagcaag tttagttcaa gtaatatcaa atattgcact taaaactcat ggtggagatt
     9061 tagctatagg ggctatggct actatttctt ctattgcaat ggtatttttg atgcctatct
     9121 ttggaataaa tcaaggagcg caacctatta taggtttcaa ttatggagct gaaaaatatg
     9181 atagggttaa aaaagcatat ttaggttcat tagtagtagc tactataatt ttatgtatgg
     9241 gtatggtagt agttatgctt ttcccagaag ctattatagg tatatttaat aaagaccctg
     9301 aacttatgaa tatatctgtt aatggattaa gaatatactt acttatgttg ccaattgtag
     9361 gcttatcagt tacaggaaca aactttatac aatctatagg aaaagcaaaa atggctatgt
     9421 tattgagcct tttaagacaa gtaattttat tgataccagc agtattaatt cttcctacat
     9481 tcttaggttt acagggtgta tggacagctc aaccagtgtc tgattttata gctacagtaa
     9541 ttacaggtat agttgtattt agagaattaa aaagatatac tcctaaaact gaaaaattaa
     9601 atgaaaatga aagactaaac gagataacta ctgagtaaaa atataaattc agataattga
     9661 gcaagaaatt gcaaaaaata cgattatatg ataaaataaa accgctgtca aggataagag
     9721 aaattctaat tatggagtga ttttatggaa tttacaaaga aaagcaaatt aaaaaatatg
     9781 tatgtaaaca tgaatgtagc tagaatgttg tctaagataa atgagtataa gggtagacaa
     9841 ctgctttaca aaaaacaacc aaaagaaatt ttagaaaact tagaaaaaaa atctttagta
     9901 gattgttctg aatctacata cattggaaat caaagagata gtagtaattt taatctagaa
     9961 aagttgataa gtaatgaagt tacacctaga agtagagagg aattgagtat tgttgaatac
    10021 agagatgtgg taaaaactat taacagtgct tatgagagta ttcccatcag ttcacaaacg
    10081 attcttgagc ttcatggata cttatataaa ttttcatcta ctagaggagg aagttataag
    10141 tcagataatg attttattga acacaattta aaacctagcg aatttataag tactgattca
    10201 agtgtcaata aagttgaaaa agctgtagaa gaaatatgtg aagcttataa tacattgata
    10261 gaggaagatg aaattgatat attaatatta atttctgcat ttgtgttaga tttcatattg
    10321 atacatccat tcaaagaagg taatataaaa atggcgagag tacttatcct attgttacta
    10381 aataaaaatg ggtatgaagt tggaagatat ataagtttag gaaagatatt tgatgatagt
    10441 tcatatgaat attatagtaa tttaaattat ttgaaagcct caataggtag tgaaaaagca
    10501 gatatgaatg catggattga gtatttttta gagacgatat taactgcata tgagaagctg
    10561 gatgatagtt taaatatatc tgataagaaa agacaaacaa aaactagtag aatagagaaa
    10621 ataataaatt ctacccttgg atattttaca aaagaagata taagagattt atgtcctgac
    10681 attccagaac ctactataaa tagagttttt aataatctaa gaaaacaaga taagatagaa
    10741 gttgttgcaa gaggaagaag tgcaaaatgg aagaaaaaat attaaaaaat gtttagataa
    10801 ctaaaatggt atagtgtttt acactatacc atttttaatg tcattagcat gagcaataat
    10861 ttaacaactt aagcaatatc aattttattt attgattatt tttgaactga aaaatggcgt
    10921 tatatggtat acctcagtgg taattaattt tggatgagaa gatataatat tacagaatat
    10981 attaggagta tatgtagaaa aaatataata aaagtgtgag gcttagtaat taacaaatta
    11041 tgtggcttca cactttttta taaaataaag atacttagca gaataatatt ttagttgata
    11101 tgtttataag atggtacttg tttgggtaaa agtataaata gtaaaaaagt agaagtaatg
    11161 tgtataaaaa cataagttac attctgtaat aatagttatt ttataattca acaaaagaat
    11221 agaatgggta tatttgtgaa ataataatat aaaataatct taggagtgag cttatgaaga
    11281 aaaaattatt atatataaat gtaaattcaa aacctgaaga cttatcttca agtaaaactg
    11341 tagcaagaaa atttataaat aaatttatgg aaaaaaacaa agattttgag gttgaagaga
    11401 tagaccttta taaagaacat ataccaagac ttgagtatca gtactttgaa aaaagaaata
    11461 gcatagttag tgaagaaaat gctaaaaatt tagacgataa ggatagaaaa gagcttacaa
    11521 agattagaaa tctttgtgac caatttgtga gtgcaagtgt atatgtaata gcagcaccta
    11581 tgtggagttt atcttttcca gcaccactta aagagtatat agattgtata attcaagatg
    11641 gaaaaactat atcttttgaa ggcaatgata aaccacaagg aattttaaat gatattgata
    11701 gaagtatggt atatatacaa tcttctg
//
LOCUS       DAFAZV010000079        11604 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFAZV010000079 DAFAZV010000000
VERSION     DAFAZV010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 11604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.082"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            337..1611
                     /locus_tag="KOU88_003686"
     CDS             337..1611
                     /locus_tag="KOU88_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBK3213512.1"
                     /translation="MQFMDVSKYIEGANLKVKTKNGETVKRIYFNNSATPLVLKNVVD
                     NLNCEIPWLTYINAPGIISEKNTLKYENVRSTILKLIDGDEEKDSVIYVKNATEGINF
                     LAKFFKDENPDKFVITTAMEHMANYLPFKVNFPTKVVGITEKGELDLCQLENILKNYA
                     GNVSLVTVTGASNVTGITTPIYEIARIAHKYGAKILVDIVQVIQHKAFSMMPHECDEH
                     IDFVVFSAHKCYSPLNGGALVGPKKFFEKFNPVLYGSGSTKFVNDNKILYANVPQRFE
                     AGYPEYFGTLAMGKALNTLNKIGLNRISKYERELFLYAKEEMSKIPNIIIYGDKSNNV
                     IIPNISFNISNMYYKDVAKYLVDNFGIETGAGVVGADIYVQKLLGINPKEAYVRFMRE
                     NPVGLVRISLGMYNTFDEVDSFIHAIKTLAFK"
     gene            complement(1818..2135)
                     /gene="trxA"
                     /locus_tag="KOU88_003687"
     CDS             complement(1818..2135)
                     /gene="trxA"
                     /locus_tag="KOU88_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBK3213513.1"
                     /translation="MVKIINNNEFINEVENKDGLVVVDFFATWCGPCKMLSPIYEALG
                     NEMVEKANFLKVDIDQSIELAQKFEVSTVPTMLIFKDGKPVDRLIGFMPKENLKNKIE
                     SYM"
     gene            2402..3154
                     /locus_tag="KOU88_003688"
     CDS             2402..3154
                     /locus_tag="KOU88_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBK3213514.1"
                     /translation="MDNIINELQNIGFTKYESQIYISLLKESPLTGYEISKLSGVPQS
                     KVYENITKLLNNNIIINVGTDPIKYIPINPNELLKNKKKEFDNSMDNLKNSLQILNKS
                     KSVEYVLNIKGDKNILKKAIEMIKNAKQEIIISCPYEEILELKKELLIAYKKNINIEI
                     LLLENKSLKGLDNIHIHGGNKTTLENKMLYKGIILIVDNDEILTGNLSEGSEAISIWT
                     KNSNILYIGVQYIKHEIYISEQIKGGYKNEQN"
     gene            3141..4022
                     /locus_tag="KOU88_003689"
     CDS             3141..4022
                     /locus_tag="KOU88_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HBK3213515.1"
                     /translation="MNKIKIKQVDAFTTIPFGGNPAGVVTDASNISDEIKQNVAKEMN
                     LSETAFVSESNVADFKVQFFTPGLEVDLCGHATIGTFHALLEEGKLNTNKSIFYQETK
                     AGVLSVELKEINNENIFMMEQNTPEFENLDNCRKELAQMIGVHEDRLLEYPIIKVNTG
                     LWWLVFGLKSLDDLKNISPDLNKIKKFSGDNNIIGITPFCIETIDKKCDYHLRSIAPY
                     VGVTEDPVCGTGNACVSSYIVHHNILDKTSFIGEQGNFINRPGKVYVNITRENNDITS
                     VKIGGSAYTVLSGEIMY"
     gene            complement(4248..5603)
                     /locus_tag="KOU88_003690"
     CDS             complement(4248..5603)
                     /locus_tag="KOU88_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004453772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBK3213516.1"
                     /translation="MSSTVKKKGKFPMGFYICSTTFSFERAAYYASKYLIYIFLTTAI
                     VHGGLGIDKGQAAIMQANLVAFTYLAPIIGGYISDRWIGARYTIPIGMLIMGVGYYLG
                     SIATTVSMVNAMIILVSIGTAFFKGNVSAVNGQLFDSQEELDTAFSVQYSFVNIGSFI
                     GTIAVGILYLKTFAKNGVLGFSQCFFIAAVLCVIGAIWFIYGWRFLGNAGKRPFKEGV
                     VAEKIEEKDKSPLTSMDKKRIWAIILISFFSVIFWVFWYLTYLAVYDYGAAFVNMNVG
                     GFDVPLAWFDSLNSLVCIVLGPVLGALWFKLASRPQGDMSLFKKTGLGLIFLGLAFLM
                     LVGAEFSRGVGAPETAKASILWIIMFGILLSLGEMLFSPLGNSFVSKYAPKKLLGVLM
                     GVWTFATFIAGKGYGYIYAFTLKFDMIKVYTIIPVILFVAAILLFLSDKTLSRLVEDD
                     K"
     gene            complement(7518..8027)
                     /locus_tag="KOU88_003691"
     CDS             complement(7518..8027)
                     /locus_tag="KOU88_003691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CarD family transcriptional regulator"
                     /protein_id="HBK3213517.1"
                     /translation="MVMFLFKIDDYIMYGMTGVCKVMDITNERFTNGIKKEYYVLSPI
                     YSNNTVIKIPVDNEKVPMRKLLSKINVLSLINDIPNMDTSWIDNEKLRSEQFKKILRG
                     GKCEELIKLVRSIDNNREYVKSIGKKTHQADDNIMKEAERLLNEEFATILDISPNEVS
                     SYISSHIPQ"
     gene            complement(8238..9647)
                     /locus_tag="KOU88_003692"
     CDS             complement(8238..9647)
                     /locus_tag="KOU88_003692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213518.1"
                     /translation="MENYFDKQAKELYNKASEIINTHSMLKANRANEKFDIDIPQDFK
                     YEFFSLVDKVNLSLMEEEDNFYGYFLFQMSREIRFDISSPTGVNFKGAKYIIYFNPII
                     FLTLDIKQMETTIKHEIHHILSMHLMRAKELKGKYSTLAINMAMDIVVNKFLNNLPPY
                     ATTLEWVNLKYSLKLEPYEPFEYYVEKIQTELDLMEVDEDGEEDDSDKYGDIEIDYSP
                     ERTHDIWDESNEIDENTLREFTEKFINSSQKGKVPAYLESMISSLKNSKGELPWNLYL
                     NRIMGTVENNKKKTITRRNRRQPNRLDLRGELRSHKAEIAVALDVSGSISDEEFKQAI
                     KEVLSIVKNYNHEITIIECDNEIRRVYKVRTEKDIKDRIRIGGGTRFSPVFEYANNKK
                     INLLVYFTDGKGENKLQVIPRGYKILWVISGRGDKISLKEPYGAVKKLTKVKTNDEIL
                     EINDVRNDGYSMNSQAPIL"
     gene            complement(9651..10781)
                     /locus_tag="KOU88_003693"
     CDS             complement(9651..10781)
                     /locus_tag="KOU88_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3213519.1"
                     /translation="MNFIDTLKSVDLILSTGEVPLIVGESGIGKTALANKLAKENDWS
                     LIVIDGNLLKEGEIGGLPTIESYVGVNSNGYKTEKKTTVYAVHNKLREIDEEISRSKT
                     VLLFIDEINRCEHTVQQELMNLILNREINGYKLHDDVKILAAMNPSSKYGSDFDYQVV
                     DMDAAQENRFVWLNMESDHTQWIKWAIDEGIERKVIEFISTFPEYLHKINEDDVRATP
                     RSYERVSKIYKVYKEKNNSIPRAVFLNVVKGNVGKVIAEEFISFIESNSEPLISYEDV
                     FLGESIDESIVERVKNESHTRLYLSAMNILKDLELNIKNDKYESNHYINRFIEFLKMY
                     PVDLMIGIMKDIRNSYIEVYKKAIENEEFVKSYFESYSLIRG"
     gene            complement(10793..11596)
                     /locus_tag="KOU88_003694"
     CDS             complement(10793..11596)
                     /locus_tag="KOU88_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213520.1"
                     /translation="MEKLRVIEMIKNNPNIIATIDNPTDEMKLLAIKENGLVLEYINN
                     PTREMQELAIDNNIRAIKFIDNPTEDMMIKAVNEGWSILDYIKNPTDKVIEMAINQAG
                     WAIKYAKNPSEELQLLAVRKNYDSIKFIKQPYESVQEEAVRISYDALRYIDSPSYNAE
                     LIAIKNNEAAISFITDLDKNKMLEFLKVNILVIKYILKKVSKDELESVLKEVLSKEDV
                     EEKYIRDFLNCSVIDRNSESIPIDKIMFIYKYGSKTAKKIAVDEKLKIM"
BASE COUNT         4184 a         1804 c         1258 g         4358 t
ORIGIN      
        1 tttttacaac tttattagtc atattcataa ttatttctaa ttagtgttta acattttatg
       61 taaaatttat aaaaaaatgt atataaatta aaataagtga ctatactaaa aatatgatac
      121 ggataaacaa taagttcaac ctatctcccc caaaatcaag tgagctacag tttcccccaa
      181 ctgtagctca ttttcgtgta atttaataaa catctcaaca agaattaatt aacaaaaccc
      241 cttataaaaa cataacatat attaaacaag ctcttgatta aaacttgagc ttttttaata
      301 aaaaacagaa tagtttatta gataaggggt ttttttatgc aattcatgga tgtatctaaa
      361 tacattgaag gtgcaaatct taaagttaaa actaaaaatg gtgaaactgt taaaagaata
      421 tattttaaca actctgccac tccattagtt ttaaaaaacg tagtggataa cttaaactgt
      481 gagattcctt ggcttactta tattaatgct ccaggaataa tctcagaaaa aaatacttta
      541 aaatatgaaa atgtacgctc tactatcctc aaacttattg atggagacga agaaaaggat
      601 tctgttattt atgtcaaaaa tgctacagaa ggaataaact tcttagcaaa attttttaaa
      661 gatgaaaatc cagataaatt tgttattacc acagcaatgg agcatatggc taattacctg
      721 ccttttaaag ttaattttcc tacaaaagtt gttggaatta cagaaaaagg agaacttgat
      781 ttatgtcaat tagagaatat acttaaaaat tatgctggta atgtatctct cgttacagtt
      841 acaggagcta gtaatgtcac aggtataacc actcctatat atgaaatagc aagaatagct
      901 cataagtatg gtgcaaagat attggtggat attgtgcaag taattcagca taaagctttt
      961 tcaatgatgc cacatgaatg tgatgagcat atagattttg ttgtttttag tgctcataaa
     1021 tgttattctc cactaaatgg aggagctctg gtaggaccta aaaaattctt tgaaaaattt
     1081 aatcctgtac tatatggctc aggttctacc aaatttgtaa atgataacaa aatactatat
     1141 gcaaacgtac cccaacgttt tgaagcagga tacccagagt attttggaac tcttgcaatg
     1201 ggaaaagcac tgaacacttt aaataaaatt ggtctaaaca gaatttcaaa atacgaaaga
     1261 gaattatttt tatatgctaa agaagaaatg agtaaaatac ctaatataat aatatatgga
     1321 gataaatcaa ataatgtaat tatcccaaat atatctttta atataagtaa tatgtattac
     1381 aaagatgtag caaaatattt agttgataac tttggaatag aaactggagc tggagtagta
     1441 ggtgcagata tttatgtaca aaaattatta ggtataaatc caaaagaggc atacgtcaga
     1501 tttatgaggg aaaatcctgt aggtcttgtt aggataagct taggaatgta caatactttt
     1561 gatgaggtgg atagctttat acatgctatt aaaactttgg cttttaaata agatttttct
     1621 attctttttt atcaataaat agagagtagt tttgttttca caaaaaaaca aattatatca
     1681 acagtcaatt tcattagcaa ttagacactc atttgtaact atacaaacta ttttacacta
     1741 tacaaacaaa aaactcatta caatgagttt ttttgtttat atatgagatt tattttaatt
     1801 acttcaattt actttaatta catatatgat tcaattttgt tttttaaatt ctccttaggc
     1861 ataaaaccta ttaatctatc tacaggtttt ccatccttaa atattagcat agttggtact
     1921 gtagatactt caaatttctg agctaattct atactttggt ctatgtccac cttcaagaag
     1981 tttgcttttt caaccatctc atttcctaaa gcttcatata ttggtgatag catcttacaa
     2041 ggtccacacc aagtcgcaaa gaaatctaca actactaaac catctttatt ttctacttca
     2101 tttataaatt cattattatt tattattttt accataatat acatctcctt tattatcttc
     2161 ttgatattaa tatactacgc cctatataac agttcaatta ggcacttttt tgtaaccgcc
     2221 tatttttaat agatttaata ttatgataaa tagatttata agattaaata tttatgagac
     2281 taaatatttc taatatattt tatttttttc ttaatatagt tgacattttt tcccttaaat
     2341 tataaaatca aattaataac tatataggta gttactaatc ttttatcaaa ggagtttcta
     2401 tatggataat ataattaatg aattacaaaa tataggattt actaaatacg aatctcaaat
     2461 atacatatca ttattaaagg aaagcccttt aacaggatat gaaataagta aattatcagg
     2521 tgtaccacaa tcaaaagtct atgaaaatat aacaaagcta ttaaacaata atataattat
     2581 caatgttgga actgacccta ttaagtacat accaataaac cctaatgaat tattaaaaaa
     2641 taagaaaaaa gaatttgaca attctatgga taatctaaag aatagcttac agatattaaa
     2701 taaaagtaaa agtgtagaat acgtattaaa cataaaagga gataaaaata tattaaaaaa
     2761 agcaatagaa atgataaaaa atgcaaaaca agaaattata atttcttgcc cttatgaaga
     2821 aattcttgaa ttaaaaaaag aactcctaat tgcttacaaa aaaaatatta atattgaaat
     2881 actactttta gaaaacaaaa gtctgaaagg tcttgataat attcatattc atggaggtaa
     2941 taaaactaca cttgaaaata aaatgcttta caaaggaatt attttgattg tagataatga
     3001 tgaaatattg acaggaaact tatcagaagg cagtgaggcc atttcaattt ggacaaaaaa
     3061 ctctaacatt ttatatattg gagttcaata cataaaacat gaaatttata tttcagaaca
     3121 aataaaagga ggttataaaa atgaacaaaa ttaagattaa acaagttgat gcttttacaa
     3181 ctataccttt tggtggaaat cctgctggtg tcgttactga tgcctctaac atttctgatg
     3241 aaattaagca gaatgtggct aaagaaatga atttatcaga aactgcattt gtttcagagt
     3301 caaatgttgc agattttaag gtacaatttt tcacaccagg tttagaagtt gatttatgtg
     3361 gtcatgcaac aataggtact ttccatgcac ttttggaaga agggaagctt aatactaata
     3421 agagtatatt ttatcaagaa acaaaagctg gtgtattatc tgtagagctt aaggaaataa
     3481 ataatgaaaa tatatttatg atggaacaga atacacctga atttgaaaat ttagataatt
     3541 gcagaaaaga acttgcacaa atgataggtg tgcatgaaga tagacttctt gaatatccta
     3601 ttataaaggt aaatactgga ctttggtggc ttgtatttgg tctaaaatct ttagatgatt
     3661 taaaaaatat ctctccagat ttaaataaaa tcaaaaaatt tagtggtgat aataatataa
     3721 ttggtataac tccattttgt atagaaacta tagataaaaa gtgtgactac catttaagat
     3781 ctatagcacc atatgttgga gttacagaag accctgtatg tggaactggg aacgcttgcg
     3841 tatcatctta tatagtacat cacaatattt tagataaaac tagttttatt ggtgagcaag
     3901 gtaactttat aaacagacct ggaaaggtat atgtaaatat aactagagaa aacaatgaca
     3961 taacttctgt aaaaattgga ggaagtgctt atactgtttt aagtggtgaa attatgtatt
     4021 aatcccatac ctaataaaaa caaataaaaa tactagctaa ctaaagctag tatttttatt
     4081 tgttattttt atttaataat catactctaa caaatattat aattatatat atcataatat
     4141 tgtatttaga agtaaaattt tatttttatt attaattagt tataaatcaa tctaatacaa
     4201 cataattaca gtagattaac ctataaaaca taataattgc ttactgatta tttatcgtcc
     4261 tcaacaagtc tacttaatgt cttatcagat aagaataata atatcgctgc aacaaatagt
     4321 attactggaa ttatagtata tactttaatc atatcaaatt taagagtaaa tgcatatata
     4381 tatccgtatc ctttaccagc tataaaagta gcaaatgtcc atactcccat aagaacacct
     4441 agaagcttct taggtgcata cttacttaca aaagagttac caagtggtga gaataacatt
     4501 tcaccaagac ttaaaagaat accaaacatg attatccata gtatactagc tttagcagtt
     4561 tcaggagctc caacccctct tgaaaattct gcaccaacaa gcattaagaa tgcaagacct
     4621 aagaatatta atccaagacc tgtcttttta aataaactca tatctccttg tggtctacta
     4681 gcaagtttaa accataatgc tccaagaact ggtcctaata ctatacatac aagtgaattt
     4741 aatgagtcaa accaagcaag aggaacatca aatcctccaa cattcatgtt tacaaatgct
     4801 gcaccataat cataaactgc aagataagtt agataccaga atacccagaa aattacagag
     4861 aagaatgata taagtataat agcccaaatt ctcttcttat ccatgcttgt aagaggagac
     4921 ttatcttttt cttcaatttt ttcagcaact acaccttctt taaaaggtct ctttcctgca
     4981 ttcccaagga atctccatcc atatatgaac catattgcac ctattacaca aagtacagct
     5041 gctataaaga aacattgaga aaatccaagt acaccatttt ttgcaaatgt tttaaggtaa
     5101 agaataccaa ctgctatagt accaataaaa gaacctatat taacaaaaga atattgtact
     5161 gaaaatgctg tatcaagttc ttcttgacta tcaaaaagct gtccatttac cgcagatacg
     5221 ttacctttaa agaatgcagt accaatcgaa actaagatta tcattgcatt taccatagaa
     5281 actgtagttg caatagaacc aagatagtat cctaccccca tgataagcat acctataggt
     5341 atagtatatc tagctcctat ccatctatct gatatatatc ccccaattat aggtgcaagg
     5401 tatgtgaatg caacaaggtt ggcttgcatt atagcagctt gtcctttatc tattccaaga
     5461 ccaccatgaa ctatagctgt tgtaaggaat atatatatta agtactttga agcataatat
     5521 gctgctcttt caaatgagaa agttgttgag cagatataaa atcccatagg aaatttaccc
     5581 ttctttttta ctgttgagct cataatttta aatcctttct taattgtatt tttatttttt
     5641 acgttttgtc caaattcttt cttttatgaa agatataata ttattatttt gtaaaacaat
     5701 ttgtaattat tattaagata attgcgcatt tatttgtaga gtacatattc tcatggaata
     5761 aaattaatac acttcttaat cataaattta aattatataa attcactatt ttcagatata
     5821 gttataaatt aatatattct catctaatac catgaaaaaa ccttcgccat atgcaattct
     5881 tattttttac gtgatagtat tttacaaact aaaatccccc ttttgtagca acttctgtaa
     5941 ttacatttta gtgctttttt aaaggagtct cgaataaagc aacatatatt ttgttcaaat
     6001 aatgttttta tttacttttt aaatttatat attacttcac ccaaccaatt ctcaacttaa
     6061 ataaataaac tactatctat tcacagatta gccctatttc ttacacatta gtttataata
     6121 aacactgtga atctaaacat aaaaactgtt attttaaagt aattacccat atattcgctt
     6181 tgatactatt tattgaggtt atactcttta tgtataatat attatttata aaatacctca
     6241 aaatatatta ttcataaaat acctcaaact gaaaactttt tcacgaatat ttatttttca
     6301 cctccccttt tttatttcac catgtaaatc gtaccataaa tatgcactta tatgcaagaa
     6361 aaaaatctat taatcgacag taaataatta gaaaaattca aattatattt atcaagtata
     6421 ttatataaaa tatttcctat gaaaatataa attaaattaa tgttcagaat tgtttttaga
     6481 tatgaaatct tgattttttt attactttac ttatttgctc aaatatattt ttgtatgcag
     6541 tatataataa tcaaattata cacttcttat aactgcattg atttgaaaat aatattaata
     6601 attaatagaa taaaaaattt aaattaaatt taaaaaaatt tgttaagttg attgaatact
     6661 tttttatgta tttaattaat tttataaatt caattatttt ctaaatttag gtatgcttta
     6721 ctatataaaa atgattttta tcttaatttt ctaaatataa gtgaatgcta tcattttaag
     6781 tatcttataa gcaatgtaac tatatatctc taataactac ttttttaaca tgcttaaact
     6841 atttataaac tattatattt atgtattaac ctaataactt tttcactaaa aaataacaat
     6901 ctattcaaaa ataaactata gtacttcttc tactttgttt caataaaata ctaaataaat
     6961 ttcgtacatc cacaattttt caggctacac tataaatata caatatttat cttagttata
     7021 agtttaagaa tatttttagt cttattttgt cgaatatgtt tttaataaaa cttcataatt
     7081 ctaagcatat ttttacactg tgttttcatg tacaaaaata atgcttacaa ataaacaaca
     7141 taaataaaac ttaaataaga tggattctat tcaacatagt atccatctta ttcattcaaa
     7201 acctaaaagg attttttata atattatata ttttaaaatc taagtaactc attatagtat
     7261 caatttcact taaagcttac aatacactta ttaatcttgc tttatattaa aaagtacaaa
     7321 aacatctaca ataacaattt aaatctttaa gtaatatcca tctcacacct aaaggagtgg
     7381 gctctccgca ctattctgta attcttcaat acaatcatta ttatttttta tataatttaa
     7441 ttatatattt tattttacca aaaccagcat acataaataa tacttaaaat agattaaata
     7501 aaggatacta aaacacttta ttgaggtata tgacttgaaa tatatgaact aacttcatta
     7561 ggagaaatat ctaaaatagt tgcaaattct tcatttaata acctttcagc ttctttcatt
     7621 atattatcat ctgcttgatg tgttttttta ccaatagatt ttacatactc tctgttatta
     7681 tctatacttc ttactaattt tattaactct tcacatttac cacctctgag tattttttta
     7741 aattgctcac ttcttaattt ttcattatct atccatgatg tatccatatt aggaatatca
     7801 tttattaatg aaagcacatt aattttagaa agcaactttc tcattggtac tttttcatta
     7861 tctacaggaa tttttattac tgtattatta gaataaatag gactcaatac ataatactct
     7921 ttttttattc catttgtaaa tcgttcattt gttatatcca tgactttgca gactcctgtc
     7981 ataccataca ttatataatc atcaatctta aacaaaaaca tcaccatcct taataaaaaa
     8041 aatagttttg acaactaaat ccaccttgcc aaaactatct gctatatatt atattttaac
     8101 acattttaag acttaaatgt aagtaaaact tatattatta aaattaaaaa atacattaac
     8161 cattgattaa tgtatttttt agatttttat aacaagcata tcaaaataaa ttaataaagc
     8221 ttatctcctg tgaataccta taaaattggt gcttggctat tcattgagta cccatcattt
     8281 cttacatcat ttatttctaa tatttcatca tttgttttaa ccttagtaag ttttttaact
     8341 gctccataag gttcttttaa tgaaatttta tctcctcttc cagaaataac ccataaaatt
     8401 ttataccctc taggtattac ttgtagttta ttttcacctt taccatcagt aaagtagact
     8461 aacaaattaa tctttttatt attagcatac tcaaagactg gagaaaatct agtacctcca
     8521 cctatcctaa ttctatcttt tatatctttt tcagttctca ctttatatac acgtctaatt
     8581 tcattatcac attctataat tgtaatttca tgattatagt ttttcactat actaagaact
     8641 tctttaatag cttgtttaaa ctcttcatca ctaatacttc cacttacatc aagtgcaact
     8701 gctatttctg ccttatgact tctaagttct cccctcaaat ctaaacgatt tggttgtctt
     8761 ctatttcttc ttgttatagt cttcttttta ttattttcaa ctgttcccat tattctatta
     8821 agatataaat tccatggcaa ttcaccctta ctatttttaa gtgatgatat catactttct
     8881 aaataagcag gaactttacc tttttgagaa ctgttaataa atttttcagt aaattctcta
     8941 agggtatttt catctatctc attggattca tcccatatat catgagttct ttcggggcta
     9001 taatcaattt ctatatctcc atatttatca ctatcatctt cctcaccatc ttcatccact
     9061 tccatcaaat ctaattcagt ctgaatcttt tctacataat attcaaaagg ttcatatggt
     9121 tcaagtttta aggaatactt taaatttacc cactctaagg tagttgcata tggtggtaaa
     9181 ttgtttagaa atttatttac tactatatcc attgccatat taattgctaa tgtactatac
     9241 tttcctttta actcctttgc tctcatcaaa tgcatagata atatatgatg aatttcatgt
     9301 ttaattgtag tctccatttg ctttatgtca agcgttaaaa agattattgg attaaaatat
     9361 ataatatatt tagctccctt aaaattcaca cctgtaggac tacttatatc aaatcttatt
     9421 tctcttgaca tctgaaacaa aaaatatcca taaaaattat cttcttcttc cataagactt
     9481 aaattcactt tatctacaag actaaaaaac tcatacttaa aatcttgtgg tatatctata
     9541 tcaaatttct cattagcacg atttgccttt agcatagaat gagtatttat aatttcactt
     9601 gctttattat aaagctcttt tgcttgttta tcaaaataat tttccataca ttatcccctt
     9661 attaaactat aagattcaaa atatgatttt acaaactctt cattttctat agctttttta
     9721 tatacttcaa tataactgtt tctaatatcc ttcataatac ctatcattaa atctacagga
     9781 tacattttta aaaattcaat aaatctatta atatagtggt ttgattcata tttatcattc
     9841 ttaatattta attctaagtc ttttagaatg ttcatagctg atagataaag tcttgtatga
     9901 ctctcatttt ttactctttc tacaatggac tcatcaatag attctcctaa aaaaacatct
     9961 tcataggata ttaatggttc agagtttgat tcaataaaac ttataaattc ttctgcaata
    10021 actttaccta cattaccctt tacaacattt aaaaatactg ctctaggaat agaattattt
    10081 ttttctttat aaactttata aattttagat actctctcat aacttctagg agtagctctt
    10141 acatcatctt catttatttt atgcaaatat tctggaaaag tggaaataaa ctcgataact
    10201 tttctttcaa taccctcatc tattgcccat tttatccatt gtgtatggtc actctccata
    10261 tttaaccaaa caaacctatt ttcttgggct gcatccatat ctaccacttg ataatcaaaa
    10321 tctgaaccat atttacttga tggattcatt gctgctaaaa tctttacatc atcatgcagt
    10381 ttatatccat taatttctct atttaaaatt aaattcataa gttcttgctg tactgtatgc
    10441 tcacaacgat ttatctcatc tataaataaa agaactgtct tacttctaga tatctcttca
    10501 tcaatttctc ttaatttgtt atgaacagca tacactgttg ttttcttttc agtcttatat
    10561 ccattagaat taactcctac ataagattct atagttggaa gaccacctat ttcaccctct
    10621 ttaagtaagt ttccatcaat aacaattaaa ctccaatcat tttctttggc aagcttattt
    10681 gctaaagctg tttttcctat tccactttca cctactatta aaggtacttc tccagtggat
    10741 aatattaagt caacgctttt taatgtgtct ataaaattca tttttctctc tcctacataa
    10801 tctttaattt ctcatctaca gctatttttt ttgctgtctt acttccatat ttataaataa
    10861 acataatttt atctattggt atactttcac tatttctatc tataacacta caattcaaaa
    10921 aatctctaat atacttttcc tcaacatctt ctttggataa tacttctttt aatacactct
    10981 ctaattcatc tttagatact tttttcagaa tgtacttaat cactaaaata ttcactttta
    11041 aaaattccaa cattttattt ttatctaaat cagttataaa gctaatagct gcttcattat
    11101 tttttatagc tataagttct gcattataac taggtgaatc tatatatctc aaggcatcat
    11161 aacttattct cactgcctcc tcttgtacac tttcataagg ttgttttata aactttatcg
    11221 aatcataatt ttttcttact gctaacagtt gtaattcttc acttggattt ttagcatatt
    11281 taattgccca tcctgcttga tttatagcca tttcaataac tttatcagtt gggtttttga
    11341 tataatccag tatactccat ccctcattta ctgcttttat catcatatct tctgttggat
    11401 tatctataaa tttaattgct ctaatattat tatctattgc tagttcttgc atctctctgg
    11461 ttggattatt tatatattct agtacaagcc cattttcttt aatagctaac aatttcattt
    11521 catcagttgg attatctatt gtagctataa tattgggatt attttttatc atttcaataa
    11581 ctctcaattt ttccataatg tgcc
//
LOCUS       DAFAZV010000080        10720 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFAZV010000080 DAFAZV010000000
VERSION     DAFAZV010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.083"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..217)
                     /locus_tag="KOU88_003695"
     CDS             complement(<1..217)
                     /locus_tag="KOU88_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213521.1"
                     /translation="MYGEIIEIYFDYWINEHMYRDILEKDKYYIESWKEIITTNELLE
                     KSLLEEDRRYVLVELNDLFNSLIEFERE"
     gene            complement(465..1791)
                     /locus_tag="KOU88_003696"
                     /pseudo
     CDS             complement(465..1791)
                     /locus_tag="KOU88_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429599.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
     gene            complement(1804..2547)
                     /locus_tag="KOU88_003697"
     CDS             complement(1804..2547)
                     /locus_tag="KOU88_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213522.1"
                     /translation="MSNLGWIKLHRKIKESPLYKDCNSKQRDILINLLLSVNHKPNKW
                     VYGGKEYEVKSGQLITSLESIANMCSKDVSIQNVRTALKKFERYGFLTNKSTNKNRLI
                     TIENWELYQSNEENQQTNQHAINKQLTTNKNINNEKSKIYSEIIEKFNITCTELSKVK
                     KLTEARKKVINARIKEYDKETVLEIIHIVSKTSFLNGSNEKGWKASFDWIMSPNNFLK
                     ILEGNYQDKSINVKVGADAYSPDDSQLKW"
     gene            complement(2568..2882)
                     /locus_tag="KOU88_003698"
     CDS             complement(2568..2882)
                     /locus_tag="KOU88_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213523.1"
                     /translation="MADTNNLEVLKTLQATLNILVKQEQEAQEKAKGYKEIQTYRRDK
                     AQLITCKEASKIYPIGESKFRQLCHSKNKGFPCIWIDNRVYIIKNKLDDWFIENANGI
                     KL"
     gene            complement(2886..3080)
                     /locus_tag="KOU88_003699"
     CDS             complement(2886..3080)
                     /locus_tag="KOU88_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003450825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213524.1"
                     /translation="MKLKLKRIEKGIKQYELAQKVGISRYYLSSLERGKSKNPSNMLM
                     LKLAQELDTSVEELFFDKGE"
     gene            3222..4082
                     /locus_tag="KOU88_003700"
     CDS             3222..4082
                     /locus_tag="KOU88_003700"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213525.1"
                     /translation="MINNTIGEKIKQYRKSLNMSRDELANKIGCSVHAIAKYEQNQRK
                     PNLDIIKKISTALSIPINRLIIEENDLDISTNNYTNLKEFDSVVKTFDNYSAKLIGNN
                     ISKFRNINNISIKELSEKINCSENEIINYENGTKMPRIEILKKIALATYTNIEDLFGF
                     PLEEIKIDNQTILYRNPQTGYIINDFLIDFINKDIDIDNTPVSHYIDKSEFDLVIHIL
                     ENYGYDINTDYKTKFEITDNVDTIKPINLNFSDFKNFSKNLNWVINGLVENFIQENSN
                     GLIENEDEEY"
     gene            4171..4923
                     /locus_tag="KOU88_003701"
     CDS             4171..4923
                     /locus_tag="KOU88_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBK3213526.1"
                     /translation="MNKSYIPKYTYKFPTNLPHGDKKYTLTYIRRMISEFVYDMGKLE
                     NNPFTFPEVQTLLDGITVGGHKLSDQNQILNIKSSWDYVIKLSNKENLSLNKDTICSI
                     HKIVAKDEALIVGDFRNGNIGIAGTTQYECIEATLLNDLFVNDINIINKITNPLEKAI
                     IINLWLSYCQFFYDGNKRTARLTSNLILISNDIGVLSIPAKHKQEYNTLMLNFYETLE
                     ADEVIKFLLEKCITFFDGYNYKSYKELFKNSN"
     gene            4913..5543
                     /locus_tag="KOU88_003702"
                     /pseudo
     CDS             4913..5543
                     /locus_tag="KOU88_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861856.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5659..5889)
                     /locus_tag="KOU88_003703"
     CDS             complement(5659..5889)
                     /locus_tag="KOU88_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213527.1"
                     /translation="MEANKTLLQILYKKIILEFSKQTGKSLEESMDYLYTSETYKLIS
                     EGVADMHCKGHIYLAQELMLENGLMYHKGYPR"
     gene            complement(5895..6374)
                     /locus_tag="KOU88_003704"
     CDS             complement(5895..6374)
                     /locus_tag="KOU88_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003361465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3990 domain-containing protein"
                     /protein_id="HBK3213528.1"
                     /translation="MIVYHGSYCVVKTPSITFSRDSLDFGKGFYVTSIKTQAINWTER
                     FKKRGKKAYLNSYSLDIDKLKENCKVKIFNSYNLEWLDFIIECRNMSDIYMKYDIIIG
                     GIADDKIYNTIELYQDNLIEKDEALKRLKYYKPNEQICITNQNVIDKYLKFRYEEEV"
     gene            complement(6374..6589)
                     /locus_tag="KOU88_003705"
     CDS             complement(6374..6589)
                     /locus_tag="KOU88_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009891555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3791 domain-containing protein"
                     /protein_id="HBK3213529.1"
                     /translation="MDERKLEFSIFCIEALAEKLNIDSEGVYKLLKHDTDILDNYIIP
                     CYEALHSQSKGYIVEDLMQVLKEKGVI"
     gene            complement(6927..8066)
                     /locus_tag="KOU88_003706"
     CDS             complement(6927..8066)
                     /locus_tag="KOU88_003706"
                     /inference="COORDINATES: protein motif:HMM:NF038233.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="retron St85 family RNA-directed DNA polymerase"
                     /protein_id="HBK3213530.1"
                     /translation="MHLKYSNLMTLESLNLPKIYNLESFSTEIGLSTTILYLLSQKQD
                     KFYHQVIIPKTKSGNRTLSIPSISMKIVQKWIKVKILDNIPVSNCAMAFRKGTNYGIK
                     MNAELHKYNTYILKLDLKDFFNNIEREKVFYLFREIGYNNYISNILSNICTFNEVLPQ
                     GGVTSPSISNLICKRLDRRLENLASKRDITYTRYADDLIFSCNDEVLLIKIKNVILDI
                     LKSEGMEINKLKTKFIRPGSRKKITGLHIDKNKVVVPRDTKRRVRAMIHYAITKEDYS
                     KLDEIKGYISFISSIEGNYISKIKSYINKIVNNGQCRLFGPIVESYNKNKIFKNLELV
                     SCIEEMDWVITKGAFYNREKYELKEVIEKSTEYGEDNINGETSPF"
     gene            complement(8253..9134)
                     /locus_tag="KOU88_003707"
     CDS             complement(8253..9134)
                     /locus_tag="KOU88_003707"
                     /inference="COORDINATES: protein motif:HMM:NF038232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="retron St85 family effector protein"
                     /protein_id="HBK3213531.1"
                     /translation="MKIKNSYLNSVNKIYTDIYKNINKEYIDVFLCGGVSTNKSCIRD
                     MVRIELENNKIRVLYPEDLFMDILSKNKSMDLLSLENFLADNSDVICIIPESPGSLVE
                     LGAFTNNKRTLENLFVVINEKYKTQKSFITTGPIKYIMNEKGSNRITYYNEDLNALIT
                     LLKFKFRKFIRMSKNKTMDVDTIIGQYYFMQLVIYFTKHISNKDLKKLINYIYTENKY
                     EKEKFNMIFSSSLKLLYKNRHIKRDIISGKISLTDKGNIYVEGMIYNLNIKNRGKLYD
                     SIRYGILYSELYGKIPL"
     gene            complement(9479..9828)
                     /gene="ssrA"
                     /locus_tag="KOU88_003708"
     tmRNA           complement(9479..9828)
                     /gene="ssrA"
                     /locus_tag="KOU88_003708"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(9986..10441)
                     /gene="smpB"
                     /locus_tag="KOU88_003709"
     CDS             complement(9986..10441)
                     /gene="smpB"
                     /locus_tag="KOU88_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBK3213532.1"
                     /translation="MAGKKILATNKRARHEYFIEETYECGIELKGTEVKSIRQGKVNL
                     SDGFASVDNSEVFLKQVHISPYEQGNIFNVDSLRVRKLLLHKHEIRKLIGATTIKGYS
                     LIPLSLYLKNGKVKVEIALAKGKKLYDKRQDMAKKDAQRRIEREMTGKY"
BASE COUNT         3698 a         1697 c         1083 g         4242 t
ORIGIN      
        1 gttctctttc aaattctatt aatgaattaa ataaatcatt tagttccacc aatacatatc
       61 ttctatcttc ttctaataaa ctcttctcta acaattcatt agttgttata atttctttcc
      121 aactttcaat atagtatttg tctttttcta aaatatctct atacatatgt tcatttatcc
      181 aataatcaaa atatatttct ataatttcac catacatgtt agtacctcct tgactttcat
      241 ctggcactta atatatactt aacttgtgta ggttagtgta cattaagtac ctaatttata
      301 aaggtagttg ttatatttat atggcaacta cctttttcta ataaattttt caatctaaat
      361 actatatatt ttaaatcttt attgcataca attaaggatt atatactttt cttctaacac
      421 tccttaaaca atagtttata tatcacttaa taaattatat tttttcatac cttcttacat
      481 tccttaaaat aaaacaaact tcctatatac caataaggtc taaagcctga ttccccatct
      541 ctatttttag caactataat ttcacttaaa ttagctccaa aacctttttc tctacgtcct
      601 aattctttta tatcctctat tcccattatc ttacaataat caagagcctc tttctctgta
      661 ggtctatgaa tatatataac tgaattagaa tccatatata tctgttttga acttctcatt
      721 actctatcac cttttggtct ttcatccttc aattcatcat tcaattgagc taactgtata
      781 attggaatat taaaatctaa agtaatcttt tttatttgcc ttgataaatc agcaaattta
      841 gcttctccaa cttctttacc ttcgtaatcc aaaatctgaa gataatcaat tataacaaca
      901 tctggtttaa tactttttat ttctctctta attcctgata ttgtattgac tgaatcatta
      961 atatagagat tattttcctg atttaaagta cttaaagcat ttatgtattt aattattttc
     1021 ttcttcattt agatttctat tcttcatttt tacaactgat attccagtta aagaagctat
     1081 gtttctaaac aaaatttgta tatcactcat ttcctcactt ataaaaagta cttttttacc
     1141 ttgaaatacc acatttctca ttatctgtaa ggatagtgct gtttttcctc ttccactttt
     1201 ggccgctatt gtaattaatt caccactata tagacctcca atagtttcat ctaaaaattt
     1261 tattcctata ttaatacctt cttcaatttc atcatttata tattcaaagg ctctttctga
     1321 tatagctgtt atactagaat ccttcttaac caatttctga ttgacttcat taatgtattt
     1381 ttctaattga tatataagtg tattatcatc tatttcccct aatttgaatt tattaaattt
     1441 atcaattata tttctatttt tatatttttc aataactata tcaatataat gagatacatt
     1501 acctatagtt ggaactattg ttgatagttt tgtcaaataa cttatacctc caacataatc
     1561 tataagcccc tttttcttta aatcttctgt aagagttatt atgtctatag gctcatccct
     1621 tttatgtata tctttcactg aattgaatat atgtttgtgt tcttgatgat aaaacatatc
     1681 ttcacttatt aatatttcaa tctcttctat tttcctcgaa tctagtaaaa tactacctaa
     1741 tatagattgt tctgcttctg tgttcttaac taaattactc atattatcca taatataaac
     1801 tccctaccac tttaattgtg aatcatctgg actatatgca tctgccccta ctttgacatt
     1861 aattgattta tcttgataat tgccttctaa tatcttaaga aaattatttg gactcattat
     1921 ccaatcaaaa cttgccttcc aacctttttc attgcttcca tttaaaaagc tagttttact
     1981 aactatatga ataatttcta atacagtctc tttatcatat tcttttatcc tagcattaat
     2041 tacttttttt ctagcttctg taagtttctt tacttttgat agttctgtac aagtaatatt
     2101 gaatttttct ataatttcac tgtatatttt acttttttca ttatttatat tcttgttagt
     2161 tgttagttgc ttgttaattg catgttgatt agtctgttga ttttcttcat tagattgata
     2221 tagctcccag ttttcaatag ttataagcct atttttgttt gttgatttat ttgttagaaa
     2281 tccatatctt tcaaatttct ttaaagcagt tcttacattc tgaatactta catcttttga
     2341 acacatattt gctatacttt ccaaagatgt tattaactgt ccagatttaa cttcatattc
     2401 tttacctcca taaacccatt tattaggctt atgattaact gacagtaata ggtttatgag
     2461 tatatctctt tgtttggaat tacaatcttt atatagtggg ctttctttta tctttctatg
     2521 aagctttatc caacctagat tactcaaata ctatcaccca cttaagccta taattttatg
     2581 ccatttgcat tttcaataaa ccaatcatct agtttatttt ttattatata cactctatta
     2641 tctatccata tacaaggaaa tcctttattt ttagaatgac ataactgtct aaattttgat
     2701 tcccctatgg gataaatttt agaagcttct ttacaagtga taagttgagc tttatctctt
     2761 ctatatgtct gtatctcctt gtaccctttt gccttttctt gtgcttcttg ttcttgtttg
     2821 acaagtatat tcaatgtagc ttgtagtgtt ttaagaactt ctagattatt tgtatctgcc
     2881 atagatcatt cccccttatc aaaaaataat tcttctacac ttgtatctag ttcttgagcc
     2941 aattttaaca tcaacatatt acttggattt ttggatttgc ctctttctaa agaagataaa
     3001 taatatcttg aaatgccaac tttctgagct aattcatatt gctttatacc tttttcaatt
     3061 ctttttaatt taagcttcat tgatttcctc cttcctcaca tacccatatt gtgccttttt
     3121 atctttctac aaaacagaat aacacccatt tcgtgcttta tcaatatatt taagtgtatt
     3181 aatacaccca tttcgtgcta taatgtattt gaggtgaaat tatgataaat aatacaattg
     3241 gagaaaagat taaacaatat agaaaatcat taaatatgtc aagagatgaa ctagctaaca
     3301 aaattggttg ctcagttcat gctatagcta aatatgaaca aaaccaaaga aaacctaatt
     3361 tagacattat aaaaaaaata tctactgctt tatcaattcc cataaataga cttattattg
     3421 aagaaaatga tttagatatt tcaacaaata attatactaa tttaaaagaa tttgattcag
     3481 ttgtaaaaac atttgataat tactcagcaa aactcatcgg aaataatata agcaaattta
     3541 gaaacataaa taatatctct attaaagagc tctcagaaaa aataaattgc tctgagaatg
     3601 aaattataaa ttatgaaaat ggaacaaaaa tgcctagaat tgaaatatta aaaaaaatag
     3661 cacttgctac ttataccaat attgaagatt tatttggatt cccattagaa gagataaaaa
     3721 tagataacca aacaatcctt tatagaaacc ctcagactgg atatataata aatgactttc
     3781 ttattgattt tataaataaa gatattgaca tagataatac tccagtttct cactatatag
     3841 acaagtctga gtttgattta gtgattcata tattagaaaa ttatggttat gatataaata
     3901 cagactataa aacaaagttt gaaattacag ataatgtaga tacaataaaa ccaattaacc
     3961 taaacttctc tgatttcaaa aacttctcta aaaatctaaa ttgggtgata aatggtcttg
     4021 ttgaaaattt tatacaagaa aattctaatg gtcttattga aaatgaagat gaggaatatt
     4081 agtactatgc attttcacaa tataaattta attgttaatt ttgatatagt cataattaga
     4141 taagaattaa ataaggaagg agctacaatc atgaataaat catatatacc aaaatacaca
     4201 tataaattcc ctactaatct acctcatgga gataaaaaat atactttaac atacattaga
     4261 agaatgataa gtgaatttgt atatgatatg ggtaaactag aaaataaccc ctttacattc
     4321 ccagaagtac aaacattact tgatggtata acagtaggtg gacataaatt aagtgatcaa
     4381 aatcaaatac taaatataaa atcatcatgg gattatgtaa taaaattaag taacaaagaa
     4441 aacttatctt taaataaaga tacaatttgc tctatacata aaatagttgc aaaagatgaa
     4501 gctctaatcg ttggagattt cagaaatggt aatataggta tagctggtac tactcaatat
     4561 gaatgcatag aagccactct attaaatgat ttatttgtaa atgacataaa tatcataaat
     4621 aaaataacta acccattaga aaaggctata ataataaatt tatggttgtc ctattgccaa
     4681 ttcttctatg atggcaacaa aagaactgct agacttacct caaacctaat acttataagt
     4741 aatgatatag gagttctatc aataccagct aaacataaac aagaatacaa cacattaatg
     4801 ctaaacttct atgaaacact agaagctgat gaagttataa aattcttatt agaaaaatgt
     4861 attacatttt ttgatggata taactataaa tcatataagg agctgtttaa aaatagcaac
     4921 taaaagagct aatggagaat gctctatcgg aaaatataaa gatggttggc gttcccgtat
     4981 aatgattggc tataatgaag atggtaaacc aataagaaaa gaattttatg gtaagactca
     5041 aaaggaagtt aaagataaac ttgatgctta taaaaaacaa tattatttaa gctctgatat
     5101 ttcagatgat aaaataactt tagagcattg gttttacaat tggttatttg aatatagaat
     5161 aaaagattta aaacctaagt catttgaaag atatgaaagc atctatcata attatattaa
     5221 agatactgat ttaggtaatg ttaaattaaa ggacttaaga gtatctcaca tacaaaaata
     5281 ttacaataga ttgcttgatt ccaataaaag tatacctact ataaggcaaa taaacactaa
     5341 actgaaaacc tgcttatcag aagctgaaaa acaaggtctt atacaacgta attattgtac
     5401 tatggtaaat ataccagttg agaaaactgt acaagtttta atgggtcatt atgatatatc
     5461 aataacttta aatatatact caagttatgg aagacaagaa agttgaagct gtagaaaagt
     5521 tggataaaat attttcattg taaaaatcaa atacatataa atattgtaat ttcatatagt
     5581 taattacaaa atcaaaataa ggatacaaat taattttata ttatcttgta tccttatttc
     5641 gtatctagtt ttaattattt atcttggata gcctttatga tacattaatc cattttctaa
     5701 cattaattct tgagccaagt atatatgacc cttacagtgc atatctgcca caccttcact
     5761 tataagttta tatgtttcag aagtatataa ataatccata ctttcttcca agctcttacc
     5821 tgtttgctta gaaaattcta atatgatttt tttatatagt atttgtaata atgttttatt
     5881 tgcttccata atcactatac ctcctcttca tacctaaact ttaaatattt atctattaca
     5941 ttttgattgg ttatacatat ttgttcattt ggtttatagt attttaatct ttttaaagct
     6001 tcatcttttt caataagatt atcctgatac agttctattg tattgtaaat cttatcatca
     6061 gcaataccac ctattataat gtcatatttc atatatatat cactcatatt tctacattct
     6121 attataaaat caagccattc taaattataa ctattaaaga tttttacctt gcagttttct
     6181 tttaatttat caatatctaa agaataacta tttaaatatg cttttttacc tcttttttta
     6241 aaacgctctg tccagttaat tgcttgtgtc tttatactgg ttacatagaa tccttttcca
     6301 aaatctaaag aatctcttga aaaggtaata ctaggagtct ttaccacaca atatgaacca
     6361 tgatatacaa tcattatatc acaccctttt ctttaagtac ttgcattaaa tcttccacta
     6421 tgtaaccttt actttgagaa tgtagtgctt catagcaagg tattatatag ttatctaaaa
     6481 tatcagtatc atgtttaaga agtttataaa ctccttctga atctatattc aatttttctg
     6541 ctaaagcttc aatgcaaaaa atagaaaatt ctagttttct ttcatccatt acaaacctca
     6601 actcctatca agcttatata atatatattt ttactaatta acaacttaaa ctgtcttaca
     6661 tttataaaaa tattatatca taaagtagat attaaaattc tgcattagtt aatctctaat
     6721 aaacaaataa agacttttta tacaataaaa tccctcccaa tgttctttca aaaaagctct
     6781 ttttttgtaa tcgaaataca atttaatgga tttcatcaca taaataaaaa atactagcca
     6841 ataaagacta gcattttcaa ttattttatc attcattttt caaaatagat aaatactatt
     6901 tacaaaactc ccacaatcac ttttatttaa aatggacttg tttcaccatt tatattgtct
     6961 tcaccatatt cagttgattt ttctataact tctttcaatt cgtatttttc tctattataa
     7021 aaagcaccct ttgttattac ccaatccatt tcttcaatac aacttactaa ttctaaattt
     7081 ttgaaaattt tatttttatt atatgattca acaataggac caaataacct acattgtcca
     7141 ttattaacaa ttttatttat gtaagatttt atctttgata tataatttcc ctctatagat
     7201 gaaataaaag atatataccc ttttatttca tctaactttg aataatcctc tttagttatt
     7261 gcataatgta tcattgctct gactcttcgc ttagtatctc ttggcactac gaccttattc
     7321 ttatctatat gtaagcctgt aatttttttt cttgaacctg gtctaataaa ctttgtcttt
     7381 aatttattta tttccatacc ttcagatttc aatatatcaa gtattacatt tttaatttta
     7441 attaataaaa cttcatcatt acatgaaaat attaaatcat cagcatatct tgtataagta
     7501 atatctcttt tgcttgctaa attttctaac cttctatcta atctcttaca aattaagtta
     7561 gatatagaag gtgatgttac tccaccctga ggcaatactt cattaaaagt gcatatatta
     7621 cttaatatat ttgagatgta attattatat ccaatctctc taaacaaata aaataccttt
     7681 tctctctcta tattgttaaa aaaatctttc aaatctaatt taagtatata tgtattatac
     7741 ttatgcaatt ctgcattcat tttaatacca taattagttc cttttctaaa agccatagca
     7801 caatttgaaa ctggtatatt atctaaaatt tttactttta tccatttttg aactattttc
     7861 attgatatac ttggtatact caatgttcga ttgcctgatt tagtttttgg tattattact
     7921 tgatgataaa atttatcttg tttttgagat aataaataaa gaatggtagt actaagccca
     7981 atctcagtac taaatgattc tagattatat attttaggca aatttaatga ttctaatgtc
     8041 attaaattac tatattttaa atgcataatg acaagtacct ccttaccata aatcttttga
     8101 gttaattgtt tcaatttttc atacttaatg ttgaataaat tgaaacaatt acgaaatata
     8161 aatacactta aattctaaca gagacgaatc atctctaact ataataagta ccatataaca
     8221 tgcgcatcta tagcaactta taacagtgtt ctctaaagag gtatcttgcc atataattct
     8281 gaatatagta taccatacct tatagaatca tacaactttc ctctattttt tatatttaaa
     8341 ttgtatatca ttccctcaac atatatattt cctttatcag ttaaagatat tttaccactt
     8401 ataatatctc tcttgatatg tctattttta tataataatt ttaaagaaga actaaatatc
     8461 atattaaatt tttccttctc atatttattt tcagtatata tatagttaat taattttttc
     8521 aagtctttat tagatatatg ctttgtaaaa tatatcacta attgcataaa ataatattgt
     8581 cctattatag tatccacatc catagtttta ttttttgaca ttcttataaa ctttctaaat
     8641 ttaaatttta aaagtgttat cagtgcattt aaatcttcat tataatatgt aattctatta
     8701 cttccttttt cgttcataat atactttatt ggtccagtcg ttataaaact tttttgtgtt
     8761 ttatattttt cattaattac tacaaataaa ttctccaatg ttcttttatt attagtgaat
     8821 gctcctagtt ctactaatga tcctgggctt tcaggaatta tacaaattac atcactatta
     8881 tcagctaaga agttctctaa actaagtaag tccatagact tatttttact aagtatatcc
     8941 ataaataaat cttcaggata taaaactcgt attttattat tttcaagttc tatcctaacc
     9001 atatctctta tacaactttt attagtactt actcccccac ataagaatac atctatatat
     9061 tctttattaa tatttttata aatatctgta tatattttat taactgaatt caagtaacta
     9121 ttttttattt tcacttaatc ctccatatta tttagtttat tcttattcta ctaattatac
     9181 tatttttaaa caaatatatt ttagatacgt ataggtagca ataatctata tactattaat
     9241 tatatcaatt atttagaaga tttaaaatca atgtcttatc ttaattctat tatttatatg
     9301 tataatacta tttttagtat atttataatt taatgtataa ttatacactt aaatgcaccc
     9361 caatataccc ccaaaaaaac ctctttttct gtggttgggg tacggttggt ggattttact
     9421 ccaaaataaa aaatactagt caataaagac tagtatttca tcattctttt ttcaaaattg
     9481 gtggagacga ggggagtcga acccctgtcc gcaaatcttt tccttgctgc atctacatgc
     9541 ttagccaact tcactaatat ctcacctcac atagcgccaa gtggcaggct ctatgcttag
     9601 ccagtcccaa ttaatctact tcaagtcgag acacccctaa agtagttccc tgcataatga
     9661 cgtccagtct tagtcggcag gaggactaag agggacgagc agcaactagg ctgctatcgc
     9721 gaaattatcg tctgcgttta ttttaaagtt ccccagtttt tacgtgaccc agagtaacac
     9781 gacatgcagc ctcaagttcc aaacccacgt cgaaaccttt acgccccctt gagtagttta
     9841 tagtccagta gacttttcgc aaactttatc accattttta ttaaattttt aatgtatata
     9901 taatataata cttttaagaa taaaaatcaa tgttatgttc tagataataa agaattttat
     9961 tctaaaaaat acagttttat ctagtttaat acttacctgt catttctctt tctatacgtc
    10021 tttgtgcatc tttcttagcc atatcttgac gtttatcata tagtttttta ccttttgcta
    10081 aggcaatctc tactttaact ttaccgtttt ttagatacaa actaagtggt ataagtgaat
    10141 acccctttat agtagttgct ccaataagtt ttcttatttc atgcttatga agtaataatt
    10201 ttctaactct taaagaatca acattgaata tatttccttg ctcatatgga cttatatgaa
    10261 cttgttttaa aaatacttcg ctattatcta cagatgcaaa tccatcactt aggttaactt
    10321 tgccttgtct tattgatttt acttctgttc cttttaattc aattccacat tcataagttt
    10381 cttctataaa atattcatgt cttgctcttt tgtttgttgc taatattttt ttaccagcca
    10441 tataaatctc accttctttg ctagaaattt gttccataaa tgttagaaat ttactaaata
    10501 tttaatgttg ccaaattatt tgactaactt gtatgataac atatttaggc attttagtca
    10561 atatttcact gatatattaa gttagttagg ctatatataa ttaagtaata taaatgtatg
    10621 aaaatagcta aaaaactact tcgaatatac ttaatactaa actaactcta accagtaata
    10681 ctaatttata aatttcaaaa caaaaatatt acatattata
//
LOCUS       DAFAZV010000081        10347 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFAZV010000081 DAFAZV010000000
VERSION     DAFAZV010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10347
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.084"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(322..579)
                     /locus_tag="KOU88_003710"
     CDS             complement(322..579)
                     /locus_tag="KOU88_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK3213533.1"
                     /translation="MKIKVEDIPVQFHAMVEIIGIDKFIEVAKLYGGTNTYIPTYKGL
                     FRYARNRDIVKQFNGVNHNELAIRYNMCVSNIKRILNENSV"
     gene            1159..1380
                     /locus_tag="KOU88_003711"
     CDS             1159..1380
                     /locus_tag="KOU88_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1659 domain-containing protein"
                     /protein_id="HBK3213534.1"
                     /translation="MEVVSTKNLSSIKLKLDAGFDDKGKAVVKSKSFANVKAEALNED
                     VYAVAEAIASLQENPIVDILKLDSTSLSK"
     gene            2197..2427
                     /locus_tag="KOU88_003712"
     CDS             2197..2427
                     /locus_tag="KOU88_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HBK3213535.1"
                     /translation="MEIKKKLVMSFKNVKDKQVSFSIENPKDDLTEENIKSVMDLIVS
                     KNIFSVGGFDLASVVEAKVVETNTTPYDLVIE"
     gene            2440..2589
                     /locus_tag="KOU88_003713"
     CDS             2440..2589
                     /locus_tag="KOU88_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvrJ family protein"
                     /protein_id="HBK3213536.1"
                     /translation="MDDSLQLLITNVGFPIALSMYLLVRIEGKLNTLSNSIDTLSKNI
                     LIFKK"
     gene            2846..3283
                     /locus_tag="KOU88_003714"
     CDS             2846..3283
                     /locus_tag="KOU88_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytTR family transcriptional regulator
                     DNA-binding domain-containing protein"
                     /protein_id="HBK3213537.1"
                     /translation="MKIHVEQGINCDDIEITIKCSALDNNIEKIISLLSIPLLDIKGK
                     KSGEIYKLNVCDILYFETVGNKTFAYYEDDVFEIDLKIYKLSKLLANTSFSRISKSMI
                     LNMDYIKSIKVISHNRMQATLKNNEKVIINRRYIKNIKEKLNI"
     gene            3540..4433
                     /locus_tag="KOU88_003715"
     CDS             3540..4433
                     /locus_tag="KOU88_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK3213538.1"
                     /translation="MQLYNTPFNTNKHLIYFFTFTLVLNWIFSLTPALLGITNTILGE
                     IIFYLAYTSPAIVGLFFISTIYPQSAKQDFIYRYLSFKEIGIKWILLTILFFALTFIT
                     SLIIGNYFNVKTSDIDWIHIAVFRPSKIAYMLLASFILSILSQEAGWRGYAIDKLLVR
                     FGFIGSSIILGLVCGIWYLGSYFTPNQIPYNLAQYSLFDAFLFIPNIVLLNFIINFVY
                     INTSRSILSAGLVHMMYYFFNIQLLLHYPIKLCVIAQYVQIIFGLIFLVYMISSNKFK
                     QKVNSEIEQIKSDDFEFELDW"
     gene            4611..5435
                     /locus_tag="KOU88_003716"
     CDS             4611..5435
                     /locus_tag="KOU88_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3213539.1"
                     /translation="MFKIGEVSKLTQISIRMLRYYDELGILKPAEIDKYTGHRLYSVE
                     QISILQRIVLLRDSKFSVAEIANIVHNWNDEFVIKELNRKKNEIQKEIKQEQQRINKI
                     DKFIEAINCDKDEIHYNVVFKKIPSYKIISLREIIPDYQSEGILWEKLSKFIKEEHIE
                     VSRQSNNNIAFYHDEEVKDNGVDIEVGMVVKKIGKNKSGFIYRETEEIDMMACTMVYG
                     PYENIAGAYESFCYWLDKNSDYQISGINRQIGHKGEHNEINPENYLTEIQIPLIKV"
     gene            5534..6142
                     /locus_tag="KOU88_003717"
     CDS             5534..6142
                     /locus_tag="KOU88_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3213540.1"
                     /translation="MGKFLRGKIMKSDSTKEQLINATIQLLSSHRDVSSITAREIVAK
                     ANVNLAMINYYFKSKEELINISIKKFLKRHMDEYKATHDTKNLAPKQQLREILIAFFD
                     FIGEHSQFIKISVPYILIQEEIVYPFEILPLIKAHYENQNNKKTEAEYRTIAYQITSF
                     IQLLFLRSNAFFKYSGIDILNVEQRNGLIDFQLDLLLVDITK"
     gene            6246..6422
                     /locus_tag="KOU88_003718"
     CDS             6246..6422
                     /locus_tag="KOU88_003718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213541.1"
                     /translation="MFFTFIGVISAILLLCTIICGLWIKLNNRNNDSNSHFTFSILSI
                     AFSLLIVVAFLVRN"
     gene            7513..8265
                     /locus_tag="KOU88_003719"
     CDS             7513..8265
                     /locus_tag="KOU88_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213542.1"
                     /translation="MLKVNQLCKSYKTGSKTYPVLKNISFEINKGEFVAIMGSSGSGK
                     TTLLNCISCFIPIDNGEIILGNNNIRNLKEKELSEVRNQQLGFVFQDFMLFDGLSVFE
                     NICVPQIIKGSQVLQMENRAINLCELFGIEHIRKKYPAEISGGEKQRTAVARALMNNP
                     DLILADEPTGNLDSKSCRTVIESFLKAKQELDATILMVTHDSFAASFCDRVIVLKDGI
                     IYKEVVKSNSRHKFLDELLEVLKEMGGAQDDN"
     gene            8255..>10347
                     /locus_tag="KOU88_003720"
     CDS             8255..>10347
                     /locus_tag="KOU88_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213543.1"
                     /translation="MTINKLYSKLRAYNWKNYTTLFFCIILSVVLVTSYALIYFSPTI
                     QNILPTGGDSRKQATMIFSVAILGCTVFTTYASSLFLKFKSKEIGIFMALGTDKKKLK
                     KLLFSEILLISVVCCFLGLILSIPVSFGIWKIFQLVIIDTREMTYHFGTQGFIYGFIF
                     SVFVTLCIFILSVKFINRTNIIDILNDQRISEPIQDVKDWYGILGIIFIILGIFLGYL
                     VPSLTINKLNYKLPSIWSFTYLLSLIGIYMIMTYIVVHAKRGKHPEKYYKNIISTSMM
                     RFMGRQTVKNMCVISFLIAGALFAVFYVPNMVTGIYDTLKNNPIDYTFTYNQRDKQVS
                     KKDIEQLADKHNIKIQNYMEIPSIELIVDGVESIYHKDGTIEKVYMKKSSYDMFFNSK
                     DFSKLIGKPITIKNGEYLAVVNKGNENQDYKYTKFISSPVTEKEIPFRYAGKIIFNGS
                     FFQNRSMNAYVLNEEDYKSFTKDLSIKNYNNSILFNVDKDTYAFANDLKKEIIKRTSK
                     EMGMFSGYDEYVKKRYESTGRKYFMDEEYPSGEGHLKLDPNNNQLYLNWKYYPNFKIL
                     QSQDMIKNMAVFLMLFIYVAIICFTAVGIIAYTRGVTIAINHKQVFMDLNRLGANNDY
                     IKFCIRNQLKKVFSYPLIAGSFLIYLFNFMIMLNNDGRIVNSEVNALLINLGFIGICG
                     VYMYLIYLLTYKKFK"
BASE COUNT         3971 a         1343 c         1296 g         3737 t
ORIGIN      
        1 taattttata aatatattat gtcatattaa ttgctatttc tttatttata tagtttattt
       61 atttattttt cccctttata caagcaattg tatcatttta tctatttttt agccaacaaa
      121 tattttcgac cattttcttt gtattctcaa tatatctcca gtatttaaca aattttttta
      181 tagaatatac aatgtattta aattaataag tagtaaattt agttaatttg tctaaaaaaa
      241 ctttataaaa catcttcttt gtctttactc ttacgtttaa caaggctatt ttcattatgt
      301 ttaaacatta ttttattata tttaaacact attttcattg agtattcgct taatattgct
      361 tacacacata ttatatctaa tagccaattc attgtggttg actccattaa attgttttac
      421 tatatcccta tttctagcat atctaaaaag ccccttatac gtaggtatat aagtatttgt
      481 tcctccatac aacttggcaa cctctatgaa cttatcaatt ccgattattt ctaccattgc
      541 atgaaattga actggtatat cctccacttt tatcttcata agttacacct cctttaagat
      601 atttttatag acttaacaaa gtttttattt aatacattat tgactaaact atatttatta
      661 gttttattga atctaataaa aaatttctta gctttaaaat taatttttgt attaacttca
      721 ataaaatttc tcataactta taactttgtt agctttaata aagattttaa tggtttaaaa
      781 gtaaaatgtt aatattggac ttttaacttt tttatttaca gattaaattt aataaaattt
      841 ttaacataag ctttaacatt taatttaaca taaactttag tacctaacat ttaactctac
      901 acatatgaaa atccatacaa aactatctca actaagcatg aatatataca aatactattt
      961 caaaacacta agaacatatc ttcacaaata acttgtaaac tttttcatca gcaaaaaagt
     1021 aaaatttttc ctataaaaat ttacacaaaa aatctttaga aattactgtt taactccgat
     1081 attatcttag atgatagtat tatagctaac aaagaaagtc gacaaatctt tgaaattaaa
     1141 tttttaggag gtaattttat ggaagttgtt tcaacaaaaa atttatctag tataaaacta
     1201 aaattggatg ctggttttga tgataagggt aaggcagttg ttaaaagtaa atcatttgca
     1261 aatgtaaaag cagaggcatt aaatgaagat gtttatgctg ttgcagaagc aatagcaagt
     1321 cttcaagaga accctattgt agatatttta aaattagata gtacatcact atctaaatag
     1381 tgtcttttaa acgtactctg ctttacaaat taaaaaatta actctttata taaaagatta
     1441 agttatataa tgcacttaat acgctataga tttggcagat tataacttca attttggtta
     1501 taactttaat atattaacgc tttgaaaaat taatatatta aacgtatttc aacttaaaca
     1561 tgttagctat tttagatgct accctacttt aatctaatta attgaaataa attaaatatt
     1621 ttctatatca gcaataacta gagtcaacaa ttaaaatact aatattgaca attgaaacac
     1681 tgatactaac aagcaaaaca ctaatattga caattgaaat actaatacta acaagcaaaa
     1741 cattaatatt gacaattgaa atactaatac taacaagcaa aacactaata ttgacaattg
     1801 aaacactgat actaacaaac aaaacactaa tattgacaat tgaaatacta atactaacaa
     1861 gcaaaacact aatattgaca attgaaatat taatactaac aagcaagaca ctaatattga
     1921 caattgaaat attaatacta acaagcaaaa cactaatatt gacaattgaa atattaatac
     1981 taacaagcaa aacactaata ttgacaattg aaacactgat actaacaagc aagacactaa
     2041 tattgacaat tgaaatatta atactaacaa gcaaaacatt aatattgaca attgaaatat
     2101 taatactaac aagcaaaaca ttaatattga taattaaaat accaatatta acaagcaaac
     2161 aattaaaata taaattatta tatcggaggt aattatatgg aaattaagaa aaaattagtc
     2221 atgagcttta aaaatgtaaa ggataaacaa gtttcttttt ctatagaaaa tccaaaggat
     2281 gatttaactg aagaaaatat aaaatctgtc atggatttga tagtatctaa aaatattttt
     2341 tcggttggag gatttgacct agcttctgtt gttgaagcca aggttgtgga aacaaatacc
     2401 actccttatg acttagttat agaatagggg gctaatttta tggatgatag tttacaactg
     2461 ttaataacca atgttggttt tcctatagct ctatccatgt acttgttggt tagaattgag
     2521 ggtaaattaa atactttatc aaacagtatt gatacattat ccaaaaatat tttgatattt
     2581 aagaagtaat ttgacaatat atgtaagtca taaaataggt ctatttgtaa aataattaga
     2641 catattctat gtgaaatact aggatatttg gataatttat ccaaatatcc atagtatttt
     2701 tttgaatttt accacctcaa atttgaattt cactgtttta tttttgaatt tcactatgct
     2761 taatttgaaa tttagaacgc atctagttgg actcaataag atataatgct attctaatga
     2821 cagtaataaa atgaggtgat gattaatgaa aatacatgtc gaacaaggta ttaattgtga
     2881 tgatattgaa ataaccataa aatgttctgc tctagataat aacattgaaa aaataatttc
     2941 attattgagt ataccgttac ttgatataaa aggtaaaaaa tcaggagaga tttataaact
     3001 caatgtctgt gatattttat actttgagac agttggaaat aaaacatttg cttattatga
     3061 agatgatgta tttgaaattg atttaaaaat atataaatta tcaaaattat tagctaatac
     3121 atctttctca cgaatatcta aatccatgat tttaaatatg gactacataa aaagtataaa
     3181 agtaatatca cataatcgca tgcaagctac tttaaaaaac aacgaaaaag ttattataaa
     3241 tcgtcgttat ataaaaaata ttaaagaaaa gctaaacatt taataaaaat ctaaagtaat
     3301 ttattaatat cactaattgc aaatttattg acctatttaa taattaataa taatataata
     3361 tattcaatat taaatactaa ttaattatat ttagtgtaaa aataattaat caaaatataa
     3421 aaaataggat attattatag gcaataacta acatcaagcg ataacttaat acatataaaa
     3481 ataaataaac aattaataaa aattaaaact tcattataaa acggaaggat agtgaaaaaa
     3541 tgcaactata taacaccccc tttaatacaa acaaacactt aatctatttc tttacattta
     3601 ctctagtatt gaactggata ttcagtctta cacctgcgtt gctcggaatt acaaatacaa
     3661 tacttggaga aatcattttt tatcttgcat atacatcacc agctattgta ggtctatttt
     3721 ttatttctac aatctatcca caaagtgcaa aacaagattt tatttataga tacctaagct
     3781 ttaaagaaat cggaataaaa tggatactat taacaatatt attttttgct ttaactttta
     3841 ttacttcgtt aataatcgga aattacttta atgtaaaaac ttctgatata gattggatac
     3901 acatagcagt gtttagacct tctaaaatag cttatatgct attagcaagt tttatattga
     3961 gtatacttag tcaagaagct ggatggagag gatatgccat tgacaaatta ttagttagat
     4021 ttggatttat aggctcttca attattttag ggcttgtttg tggaatctgg tatctagggt
     4081 cgtattttac acctaatcaa ataccatata atttggcaca atactcccta tttgatgctt
     4141 ttttatttat accaaacatt gtacttttaa actttataat taattttgta tatatcaata
     4201 caagtagaag cattttatca gctggattag ttcatatgat gtactatttt ttcaacattc
     4261 aattacttct acactaccct attaaattat gtgtaatagc tcaatatgta caaataatat
     4321 ttggtttaat atttcttgta tatatgattt cttctaataa atttaaacag aaggtaaatt
     4381 ctgaaattga acagataaag tcggatgatt ttgaatttga gttagactgg taattttaat
     4441 atgaattata aattaatata atctatgatt tgatacgatt actacttaaa tataatttac
     4501 tctctataat ttattgcaac atctggaaaa taattgtatt tccacaaacg cttgaagtat
     4561 ataaaaacaa aatatatact gattataagt gaaaaggagg tcatattttc atgtttaaaa
     4621 taggagaggt ttcaaaacta acacaaattt ctattcgtat gttgcgttat tatgatgaac
     4681 ttggtatttt aaagcctgca gaaatagaca aatatacagg tcatagatta tactcagttg
     4741 aacagatttc aatattacaa agaattgtat tattgagaga ttcaaaattt agcgttgcag
     4801 aaatagcaaa tatcgtacat aattggaatg atgaatttgt aattaaggaa ttgaatagaa
     4861 aaaagaatga aatacaaaag gaaataaagc aggaacaaca aagaataaat aaaattgata
     4921 aatttataga agctataaac tgtgataaag atgaaattca ttacaatgtt gtctttaaaa
     4981 agattccaag ttataaaatc atatcactta gagagataat tccagactac caatctgaag
     5041 gtatactctg ggaaaagcta tctaaattta tcaaagaaga acatatagaa gtatcacgtc
     5101 aatccaacaa taacatagct ttttaccatg atgaagaagt caaagataac ggtgtagata
     5161 ttgaagttgg aatggttgta aagaagattg gaaagaacaa atctggattt atatatcgtg
     5221 agacagaaga aattgatatg atggcatgta ctatggttta tggtccatat gaaaatatag
     5281 ctggtgcata tgaatcgttc tgttattggt tagataaaaa tagtgattat caaatatcag
     5341 gtataaatag acaaatcggt cataaaggtg aacataatga aataaatcct gaaaattatc
     5401 ttacagaaat tcaaatcccc cttataaaag tctaatcgat tagtacttaa atacttaagt
     5461 actaatcacc cattgacatc ccaaaatttt catgatagta tctaaacgtg tattaaacat
     5521 gtttaatttt tttatgggga aatttttaag gggaaaaatt atgaaatcag attcaacaaa
     5581 ggaacaatta attaatgcta caatccagtt actatcttca catagagatg tttcaagcat
     5641 tacggctaga gaaattgtag ctaaagcaaa tgtcaattta gctatgatta attattattt
     5701 taaatctaaa gaggagttaa ttaatatttc tattaaaaaa tttttaaagc gtcatatgga
     5761 tgaatataag gctacacatg atactaaaaa tttagcacct aaacagcaat taagggaaat
     5821 actaattgca ttttttgatt ttataggtga acatagtcaa tttataaaga tttctgtacc
     5881 ctatatattg atacaggaag aaattgttta tccatttgag atactacctt taattaaggc
     5941 tcactatgaa aatcagaata acaaaaaaac tgaagctgaa tacagaacta ttgcgtatca
     6001 aataacttca tttattcagt tgctttttct tcgttctaat gcttttttca agtatagtgg
     6061 tattgatatt cttaatgttg aacagagaaa tggtttaata gattttcaat tagatttatt
     6121 attggtagat attacaaaat aatactatat taatttttta tgtacatttt tttattttat
     6181 ggtaacgttt gaaaatattc tcattgacta aaaatacttg cattaaataa gggggaggaa
     6241 ttttaatgtt ttttacattt ataggagtaa tatcagcaat tttattgttg tgtacaatta
     6301 tatgtggttt atggataaaa cttaataatc gtaataatga ctctaattct cactttactt
     6361 tttcaatact ttcaattgct ttttcactgt taattgtggt ggccttttta gtaagaaatt
     6421 aatgtctttg ttatgctggg gtttattatt atagattttt attattgcat gatttttact
     6481 atattatagt atttttatta tattacaggg tcttatttat tatagtgttt tgttgttaca
     6541 gcattttatt atattacaga gtcctattta ttataggatt tttattatat tgtaaaatct
     6601 tatttattat aggattttgt tatattacag acttttatta tattgcaatc tcttatttat
     6661 tgcagtgttt tgttattaca gtatttctat tatattgcaa actcttattt attatggtgt
     6721 tttgttattg caacatttct attatattgt aaagtcttat ttattacagt tctttattat
     6781 actacagacc tttattatta cagcatttct attacattgc aaagtcttat ttattacagt
     6841 tctttattat actacagact tttattatta caacatttta ttattttaac ttctttacta
     6901 taatatagta atattttaat atctcaaaat catatcaatc acttttcagc atagtctaaa
     6961 atacttccac tttctaaaat tatctatcat acctatacta ataatacttt ttaacctttt
     7021 tattatacat ttcaattgtt tttaacaacc tatttatttc caaaactcca atatattttc
     7081 tcaattacat tgtgttaata acccctaaat cctttcaaat tatttacaat acattccatt
     7141 aaataatctt actgctctat aattcttttt ttctttttaa ccctactata cattatttac
     7201 atcatttttt tcaatacaac attcgttatt ctataacctt tttactttta ctatatacct
     7261 cttttctaac tacaccttca atgttccaca tcatattgct ttagcacaac aattaatacc
     7321 taaaaataac cctctaaatc ctccaataat ataatcaatt taactataat aataacctct
     7381 cacactatcc aaacaatata ttttcaaaca ttacaaaaaa acatccaact attacaatat
     7441 atctcatatc cctcctcccc tttcaaatgc tatcattgac ttacaagata aatgaaagtg
     7501 aggatgatat atatgcttaa agtaaaccaa ttatgtaaat catataaaac aggcagtaaa
     7561 acatatcctg tattaaaaaa tatttctttt gaaatcaaca aaggagaatt tgtcgcaatc
     7621 atgggttcat caggaagtgg aaaaactact cttttaaatt gtatttcatg ttttatccca
     7681 attgataatg gggaaataat tcttggaaat aataatataa gaaatttaaa agaaaaggaa
     7741 ctttcagaag ttagaaatca acaactagga tttgtattcc aagatttcat gctatttgat
     7801 ggtcttagtg tatttgaaaa tatatgtgtt ccacaaatta tcaaaggtag tcaagtctta
     7861 caaatggaaa accgtgcaat taatctatgt gagctatttg gtattgaaca tatcagaaaa
     7921 aaataccctg ccgaaatatc tggtggagaa aaacagcgta cagcagtagc aagagcactc
     7981 atgaacaacc cagatttaat attagcagat gaaccaactg gtaaccttga tagtaagtct
     8041 tgtcgtacag tcattgaatc atttttaaaa gcaaagcaag aattagatgc tactatactc
     8101 atggttacac acgatagctt tgcagcaagc ttctgtgacc gagttattgt gcttaaagat
     8161 ggaataattt ataaagaagt tgtaaaatca aattcaagac ataaattcct agatgaatta
     8221 ctagaagttt taaaagaaat gggaggcgct caagatgaca attaataaat tatacagtaa
     8281 acttcgagcc tataattgga agaactatac aactttattc ttttgtataa tactttctgt
     8341 ggtattagta acttcatatg ctctaattta ttttagccca acaatacaaa acatacttcc
     8401 aactggtgga gatagcagaa aacaggctac aatgatattc tcagttgcta tattaggatg
     8461 cactgtcttt actacatacg catcttccct ctttttaaaa tttaaaagca aggaaattgg
     8521 tattttcatg gctctaggaa cagataagaa gaaattaaaa aaacttctat tttcagagat
     8581 attgttaatt tcagtagtat gctgtttttt aggtcttata ttaagtattc ctgtatcttt
     8641 tggtatatgg aaaatatttc aattagtgat tattgatacc agagaaatga catatcattt
     8701 tggaactcaa ggattcatat atggatttat atttagtgta tttgtgacat tatgcatatt
     8761 tatactttct gtaaaattta ttaatcgtac aaatataatt gatatattaa atgaccagag
     8821 aatatctgaa ccaatacagg atgtaaagga ctggtatggt atattaggta taatttttat
     8881 tatactcggt atttttctag gatatctcgt accttcacta actataaaca aattaaatta
     8941 taaactacca tctatatgga gctttactta tctactctct cttattggaa tatatatgat
     9001 tatgacatac atagttgtac atgctaaaag aggaaaacat ccagagaaat actataaaaa
     9061 catcatatca actagcatga tgagatttat gggaagacaa acagtaaaaa acatgtgtgt
     9121 tatttcattt ttgattgcag gagcattatt tgctgtattc tatgttccta atatggttac
     9181 aggtatctat gatactctta aaaataaccc tatagattat acttttacct acaatcaaag
     9241 agataaacag gtatcaaaaa aagatattga acaattagca gataaacaca atataaaaat
     9301 tcaaaactat atggaaattc cttctataga attaattgtt gatggtgtag aatcaatata
     9361 tcataaagat ggaactatcg aaaaggtata tatgaaaaaa agctcctatg atatgttctt
     9421 taattccaaa gatttttcca agctaattgg caaaccaata actataaaaa atggtgaata
     9481 tcttgctgtt gtaaataaag gaaatgaaaa tcaagattat aaatatacca aatttatatc
     9541 aagcccagtc acagaaaaag aaatcccctt tagatatgct ggaaaaataa tatttaatgg
     9601 ttcttttttt caaaatagaa gtatgaacgc ctatgtcctt aatgaggagg attataaatc
     9661 atttactaaa gatttatcca taaaaaatta caataattct atactattta atgtagataa
     9721 agatacctat gcttttgcca atgacttaaa gaaagaaatt ataaaaagaa catctaagga
     9781 aatgggcatg ttcagtggtt atgatgaata cgtaaaaaaa cgttatgaat caactggaag
     9841 aaaatatttt atggatgaag aatatccaag tggtgaaggt catttaaaac tagacccaaa
     9901 caacaatcag ttgtatctta attggaaata ctatcctaac tttaaaattt tacaaagcca
     9961 agatatgata aaaaacatgg cagtcttctt aatgttattc atatatgtgg caatcatatg
    10021 ttttacagca gtaggaatca ttgcatatac aaggggtgtt actatagcta taaatcacaa
    10081 gcaggtcttt atggatttaa atcgattagg agcaaacaat gattatataa agttctgtat
    10141 tagaaatcaa ttaaagaaag tattttcata ccctcttatt gcaggaagtt ttttaattta
    10201 tctgtttaat tttatgatta tgttaaataa tgatggtaga atcgtcaata gtgaggtcaa
    10261 tgctcttttg ataaacttag gttttatagg gatttgtggg gtttatatgt accttatata
    10321 tctattaact tataagaaat tcaaaaa
//
LOCUS       DAFAZV010000082        10209 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFAZV010000082 DAFAZV010000000
VERSION     DAFAZV010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10209
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.085"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            152..1033
                     /locus_tag="KOU88_003721"
     CDS             152..1033
                     /locus_tag="KOU88_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBK3213544.1"
                     /translation="MPAYLFDSNSIANIYRVFPISFSFIVTGLYFSYKNNKNNKINFE
                     AVLEDKKNLIFLLSLMFGMYLYLCLSLSIYYTVGNVLILKLYGIKSAIIVLVGNYIAE
                     RYSFRITQIKGYDIKNQIEYVESIKTEYEINKLNDIVYTDLLTGFYNRPFVNQKLSEW
                     TSNHYKFTLCFTDLNSLKPVNDKFGHQFGDKYISTTAQIIKKLINVENSLLFRYGGDE
                     FLFLLQNTSCVEAEKIMININYELSKLSNTDEYPYALSISYGLVEWDGISDIETLISK
                     ADSLMYENKLKNKSTLN"
     gene            1242..1391
                     /locus_tag="KOU88_003722"
     CDS             1242..1391
                     /locus_tag="KOU88_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013378937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBK3213545.1"
                     /translation="MTTVAEGIETSFQKDFLQEIDCDMLQGYVFSRPLPIKDFEKLMF
                     QNSSN"
     gene            complement(1651..4218)
                     /locus_tag="KOU88_003723"
     CDS             complement(1651..4218)
                     /locus_tag="KOU88_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002602373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate, phosphate dikinase"
                     /protein_id="HBK3213546.1"
                     /translation="MIYYVLPLEHKQATIEIIGGKGMSLSKLLTAGIPVPDGFHVTTA
                     SYQIFVETNHIQSRINKLLDGIDSNNTSQLEDVSKKIGELFHNGEMPQEVSDAIKTAY
                     AGLGNISVAVRSSATAEDLPDASFAGQQETYLNIQGEDKVIDAVKRCWASLWTARAIA
                     YRVKNNIKHEIVALAVVVQKLAFSDSSGIMFTLNPINGRRSEMIINAAWGLGEAVVSS
                     LVTPDTIVVDKDSERIISYEVANKEIMTVRTSEGTEETMVPERLRKKYALTRNQVMQL
                     IQLGKKIEKYYQMPMDVEWALEKDKLYIVQARPITVLPPEWVLPEQDVVYTKGSLAEH
                     LPNPVTPLFATLGLEIVNRASELLWIDMFGKSAKKLLPKNGAYTVINGYVYLSAKSKP
                     FLIAIKSLSPRSLRRTLMNSVARWETARKGYEDAIKQWEEKPMHTMNAHQIMEGIQTI
                     FYAACIYFTRIQLTLPAASISETLFTKLFQGAVRRAGITDTSVFLLGFDTIVLQSEKE
                     LWGISEWVKQNNSINLYLQNSSAIKIAEDFMSSVVPVGVSQEVWIEWKNRINKYFKEF
                     GRTAYEFDFAHSTPQETLTPTFESVKTFVEGKGESPFLRQTTFEKRRKHAEEEILQHI
                     GGLRKKLFFKLLHWAQETSPMRENAIYLMGMGHPLIRCMFQEISERFIRGGAISHLDD
                     IYWLTKSELEVLIEQLDKNKSLSDMNGIIPVRKAELKKYMGYVSPSKLPEKNKKTISQ
                     AQQKQKDGKIVLTGIGTSTGVVTAPACVLNSPADFESFQPGSVLVAVTTTPAWTPLFS
                     SASAIVTDIGGPLSHSSIVAREYGIPAVMATHIATRTIKSGQMITVDGLAGTVTFDE"
     gene            complement(4221..4826)
                     /locus_tag="KOU88_003724"
     CDS             complement(4221..4826)
                     /locus_tag="KOU88_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3213547.1"
                     /translation="MPKGIVLTPEQQAERREKIVAVALSLMAENGFQKTSMREIAVLA
                     NMGKSSLYDFFKTKDEIVVYAVEKEIEKTIQQVHRIIDGEPSPQQCLRKIMLNHLRFP
                     EQYRTVLMWLNTESDYLEEEYRKRLKDARYAYQDIIKSVIDNGVTTGIFRKTNTALVT
                     RLLINSMLSISYTSRPSDSLEKMLDETMNIFLHGIMNDGGE"
     gene            complement(5200..6660)
                     /locus_tag="KOU88_003725"
     CDS             complement(5200..6660)
                     /locus_tag="KOU88_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HBK3213548.1"
                     /translation="MFNELKTKENVYKNLINGKWVESNSRKPIEIYSPIDNSLVGKVQ
                     SMTKHEVDEVIKNTKESIKVWAEMPVYKRGNIFHKAADLLLENIDEIANILVLEIAKD
                     IKSARAEVERTADFLRYTADVGKNMEGEAISGDNFPGGTRNKMSYVSRVPLGTVLAIS
                     PFNYPVNLSMSKIAPALIGGNAVVLKPATQGAISALHVVEIMRKAGIPDGVLNTITGR
                     GSEIGDYVVTHKGINFINFTGSTEVGQHISKISGMVPLLLELGGKDAAIVLEDADLDF
                     AAKNIVSGAYSYSGQRCTAVKRILVQESVADKLVGKIKPLVEKLTIGNPMDEVVITPL
                     IDNKATDFVQGLVDDALHKGAKLITGNVRKNNLFYPTLLDNVNVDMKIAWEEPFGPVL
                     PIIRVKDINQAIEIANQSEYGLQSSVFTSDIDKAFYIADKLEVGTVQINNKTERGPDH
                     FPFLGVKASGMGTQGVKYSIEAMTRPKAVVVNVREL"
     gene            7022..7600
                     /locus_tag="KOU88_003726"
     CDS             7022..7600
                     /locus_tag="KOU88_003726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3213549.1"
                     /translation="MAKSFTEIEKDNIRKRLISECEINWSKYGYKKTNIDELCSKSGI
                     AKGSFYTFFDSKEKLFFEVLNGIQNRLISSVDEILSNMPPKEGFAKSLKMLYRLYDKN
                     PFLYSPNNPDFISLINKLPQDMFLQLESNNIQSFYDLIERHNLKLKIEKEKVFGVCNA
                     LLSSLLVKENIEYNYIEVFDFMVDNLVEHILE"
     gene            7891..9141
                     /locus_tag="KOU88_003727"
     CDS             7891..9141
                     /locus_tag="KOU88_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK3213550.1"
                     /translation="MVKSSNTFNKNFNLMILGQIISLFGASILKFALSLYILDITGKA
                     EIFATILAVSSIPIIVFSPIGGAIADIFNRRNLMVIFDFSSSLTVLILAVFLFNNNGS
                     ILLVGIIMTILSVISTMYQPTVQSSTPLLVDNEHLMNANGIVAGVASLTNIAGPVLGG
                     VLYGVIGINAIIVISCVSFFLSAIMEIFIQIPFIKQEQNSNIIKTIFTDIKDGIVHIC
                     KENRFILKILFLAIAINLFLSSMLIVGIPYIVKITMGASNFLYGLAEGAISFSSLVAA
                     VSIGIFSKHLKITNLHISFIICAVMFIPMAVSVYPFILNTGFPVPFLIFIVSSMLIFF
                     TTTLISIYVITVTQLKTPNELLGKVMSILFAGTAIAMPLGQVMYGKLFDLLSDRVYII
                     ILGVGFITLLIAFVSKITLRNENL"
     gene            9302..9871
                     /locus_tag="KOU88_003728"
     CDS             9302..9871
                     /locus_tag="KOU88_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBK3213551.1"
                     /translation="MSYMPTLEQAWEILRKYNKEEFHIRHAQIVSGVMRYYAKEYDPE
                     RVEFWEIVGLLHDLDFEMYPDEHCVKQRELMTELDLDKSIIDSTISHGYGLTGSDVKP
                     EQFMEKVLFAVDELTGLIGAAAIMRPSKSVSDLELKSVKKKFKDKSFAAGCSRDVIRS
                     GAEMLGWELDKLIQTTIEAMRSLIPEMAI"
BASE COUNT         3424 a         1747 c         1483 g         3555 t
ORIGIN      
        1 ttggacaatt tttatgttga ttttattcat acaaattaaa gtaacttata aaatctccac
       61 aataaaaaac attttttatt cactaaactg ctccatcatt ggtttagcaa taaatatatt
      121 ttttaggtct ttaatgtcaa tagtgttaaa tatgccagca tatttatttg atagtaattc
      181 tattgcaaat atttacagag tatttcctat atcatttagc tttatagtta caggactata
      241 tttcagttat aaaaataata aaaataataa gattaacttt gaggcagttt tagaggacaa
      301 aaaaaactta attttcttat tgagccttat gtttggaatg tacttgtatc tatgtttgag
      361 tttgtcaata tactatactg ttggaaatgt attgatttta aaattatatg gaatcaagtc
      421 tgccataata gttttggtag gtaactatat tgcagaaaga tatagcttta gaattactca
      481 aataaaaggt tatgatatta aaaatcaaat agaatatgta gaaagtataa agacagagta
      541 tgaaattaat aaattgaatg atattgtata tacagattta ctgacaggct tctacaatag
      601 accttttgta aatcaaaaac tatcagagtg gacatcaaat cactacaaat ttaccttatg
      661 ttttactgat ttaaatagct taaaacctgt aaatgataaa tttggacacc aatttggtga
      721 taaatacata tccactactg ctcaaataat aaaaaaactt ataaatgtag aaaattcctt
      781 actatttaga tatggtggag atgaattttt attcctttta cagaatacaa gttgtgtaga
      841 agcagaaaag ataatgatta atataaatta tgaattatca aaattaagta atactgacga
      901 gtatccttat gctctttcca taagctatgg attagttgag tgggatggaa tatccgatat
      961 tgaaacttta atatcaaagg cagattcttt gatgtatgaa aataagctta aaaataaatc
     1021 tactttaaac tagctagtta agatattcta caaaatatat gttataagag agtactaaga
     1081 atgtcaaaat atatagattt tgcaaatatt gaatacagtt tactaatgaa tgcactggat
     1141 ataagtgtta gtaaacacct attagatgaa cactttactg ttgtttgggc taatgactgt
     1201 tattatgaaa tgtttggcta tacctagcta aaaagttaaa aatgaccact gtagccgagg
     1261 gaatagagac cagttttcaa aaagatttct tgcaagaaat agactgtgat atgttacaag
     1321 gatacgtgtt ctctagacct ttaccaataa aagactttga aaaacttatg tttcaaaact
     1381 cctccaatta acaatataaa attgcttatt ataagtgata ttattgtatc aacaaataaa
     1441 ggaattgtct caaaattgat tttttctaat caaattttta ttttgagaca ttctcatttt
     1501 tttgcataag aaaatcccca ccaagctacg gtttttctta ccgctgttcg gtgggtatta
     1561 gtagtattat gaaatctgaa aactttaagt attactactt ccgctagcgc aatcacaaag
     1621 gtcgaaagct tcaaagcgaa aataggcttt ttactcatca aacgtcaccg tacctgccaa
     1681 cccgtccacc gttatcattt gtccgctctt aatagttcgt gtggcaatgt gtgtagccat
     1741 aacggctggg atgccatatt cacgtgcgac aatgcttgaa tggctaagag gaccaccaat
     1801 gtccgttaca atcgcacttg cagatgaaaa taatggtgtc catgctggag ttgtggtaac
     1861 tgcaaccaaa acacttccag gttgaaagct ttcaaaatct gctggactat tcagtacaca
     1921 agctggagct gtcacaacac cagtactggt accaatgccc gtcaacacaa ttttcccatc
     1981 tttctgcttc tgttgtgctt gtgatatagt ttttttgttt ttttctggca acttggatgg
     2041 tgacacataa cccatgtatt ttttaagttc agcttttcga acaggtatta tcccgttcat
     2101 atcagataga gacttgtttt tatccaactg ctctataagt acctccaatt ccgattttgt
     2161 gagccaataa atatcatcta aatgtgaaat agctcctcct cgtatgaatc gttctgagat
     2221 ttcctgaaac atacaacgaa tcagaggatg tcccattccc atcaaataaa tagcattttc
     2281 acgcatagga gaggtttcct gtgcccaatg gagcaactta aaaaatagtt ttttacgcaa
     2341 tccacctatg tgttgtaaaa tctcttcttc tgcatgtttt ctacgctttt caaacgtggt
     2401 ctggcgtaaa aaaggacttt ccccttttcc ttccacaaat gtttttacgg attcaaaagt
     2461 tggtgtaagt gtttcctgcg gtgtggaatg cgcaaaatca aactcataag cggtacgacc
     2521 aaactcttta aagtacttat tgattcgatt tttccattct atccatactt cctgtgaaac
     2581 tccaacaggc acaactgaag acatgaaatc ttctgctatc tttattgcag aactgttttg
     2641 cagataaagg ttgatgctgt tattttgctt tacccattct gaaatacccc acaactcctt
     2701 ttccgattgc agaacaatcg tatcaaaccc aagcaggaaa acggaagtat ccgttatacc
     2761 agcacgtcga actgctcctt gaaataattt tgtaaataat gtttcactga tagaagcagc
     2821 aggcaatgta agctgaatcc ttgtgaaata aatacatgcg gcataaaata ttgtctgaat
     2881 accctccata atttgatggg cgttcatagt atgcatgggc ttttcttccc attgtttaat
     2941 agcatcctca tatccttttc gtgccgtttc ccagcgtgca acgctgttca taagtgtcct
     3001 acgtaaagag cgtggggaaa gggatttgat agcaatcaaa aatggctttg atttagcaga
     3061 aagataaaca tatccattaa taaccgtata tgccccgttt tttggtaata attttttcgc
     3121 acttttacca aacatatcta tccataaaag ctctgatgca cggtttacga tttcaagacc
     3181 aagcgtggcg aacaaaggtg taacaggatt tggcaagtgt tctgccaaac ttccctttgt
     3241 gtatacaaca tcctgttctg gcaataccca ttctggtggc agaacagtaa ttggacgagc
     3301 ctgaacaatg tacaatttat ctttttccag tgcccactct acatccatag gcatttgata
     3361 atacttctca attttctttc caagctgtat cagttgcatt acctgattac gagtaagagc
     3421 atattttttt ctcaaccttt caggaaccat ggtttcttct gttccttctg aagtacgaac
     3481 cgtcataatc tctttatttg ccacttcata cgatataatt cgttcggaat ccttatccac
     3541 cacgattgta tcgggtgtaa ctaagctaga aaccaccgct tcaccaagcc cccatgcagc
     3601 gttaataatc atttcgctac gtctaccatt gattgggttt aacgtaaaca taataccaga
     3661 tgaatcggaa aatgcaagct tttgtactac aacagcaagt gcgacaatct cgtgctttat
     3721 attattcttc acacgataag caatagcacg agctgtccat aaggaagccc agcatctctt
     3781 tacagcgtca ataactttat cttcaccttg tatgttaaga taagtttcct gctgacctgc
     3841 aaaagaagcg tcaggtaaat cttcagcagt cgcagacgaa cggacagcca ccgatatgtt
     3901 ccctaatccg gcataagccg ttttaattgc atccgacact tcctgtggca tttctccatt
     3961 atggaaaagc tcccctattt tcttagatac atcttcaagt tggctggtat tattggaatc
     4021 aataccatct agcagtttat taattcgaga ctgaatatgg ttcgtctcaa caaaaatctg
     4081 gtatgaagca gtcgtaacat gaaaaccgtc tggcacaggg atgcctgctg tcaatagttt
     4141 tgataaagac atcccttttc caccaataat ttcaatggtt gcttgtttat gttccagtgg
     4201 caagacataa taaatcataa tcattcacct ccatcattca taattccgtg cagaaatata
     4261 ttcattgttt catccaacat tttttccaaa ctatccgatg gtcttgacgt gtagctgatt
     4321 gataacatgg agttaattaa caaacgtgtc acaagagcgg tattcgtttt gcgaaagatg
     4381 cctgtggtca caccattatc aattaccgat tttataatat cttgatatgc ataacgagca
     4441 tctttaagtc tctttcgata ctcttcttct aaataatcag attctgtatt taaccacatc
     4501 agtacagttc tatactgctc tggaaatcta agatgattaa gcatgatttt tctaaggcac
     4561 tgttgtggtg aaggttcacc atcaataatc ctatgaactt gttggatagt tttttctatt
     4621 tctttctcaa ctgcatatac aacaatctcg tctttcgttt tgaaaaaatc gtatagactt
     4681 gactttccca tgttggctaa aactgcaatt tctctcattg atgttttttg gaatccattt
     4741 tcagccatga gactcaaagc aacagcaact attttttctc ggcgttctgc ttgttgttcg
     4801 ggtgtaagca caattccttt tggcataggg cgatacctcc ttttagcgac cactggtcgt
     4861 ttctttttta tttatcatac agcgaccaac ggtcacttgt caaggttaat ttttttcatt
     4921 gtatatggta ctcgagataa aaatgttcat tttagaaatt gctctattta agtagaaata
     4981 ggcttcatca ttagaaaaca agactataaa tttgagatat ttatcatgtt caaatttcat
     5041 caatatcaaa gtttaagata ttaataaaaa aagaattact aagaaataac atataaagat
     5101 tcaaaaaagg agttgaactt aaaattcaat tacaaaaaat caaatttaag acaactcctt
     5161 tattctttat ctctactatt ctttatctct atttatttat tacaactccc taacatttac
     5221 cactactgcc ttaggtctag tcatagcctc aattgaatac ttaacacctt gagttcccat
     5281 accagatgcc tttacaccta aaaatgggaa gtggtctgga cctctttcag tcttattatt
     5341 tatttgaaca gtaccaactt caagtttatc agctatataa aatgccttat caatatcact
     5401 tgtaaatact gatgattgaa gcccatactc tgattgatta gcaatttcaa ttgcttgatt
     5461 tatatcttta actcttataa ttggaagtac tggaccaaat ggttcttccc aagcaatttt
     5521 catatcaaca tttacattat ctaacaatgt tggatagaat aaattatttt ttctaacatt
     5581 gcctgttatt aactttgctc ctttatgtaa tgcatcatca accaaccctt gaacaaaatc
     5641 agttgcttta ttatctataa gaggagtgat aactacttca tccattggat ttccaattgt
     5701 caacttctct accaatggct ttatttttcc gactaattta tccgccacac tctcttgtac
     5761 taaaattctc tttactgccg tacatctttg tcctgaatat gaatacgctc cagatactat
     5821 attcttagct gcaaaatcta agtctgcatc ttctaatact atagccgcat cttttccacc
     5881 aagctccaat aataatggta ccattccaga tattttagat atatgctgac caacttcagt
     5941 actaccagta aagttaataa aattaattcc tttatgcgtt acaacataat cccctatctc
     6001 actaccccta cctgtaatag tattaagtac tccatctggt atcccagctt ttctcataat
     6061 ttctaccaca tgaagtgcgc taatagcccc ttgtgtagca ggttttaata cgactgcatt
     6121 tccaccaata agtgctggag caatctttga cattgataaa tttacaggat aattaaaagg
     6181 agatatagct aaaacagtac ctaatggaac ccttgaaaca taagacatct tatttcttgt
     6241 tccaccaggg aaattatctc cactaatggc ttctccctcc atattttttc ccacatcagc
     6301 tgtgtatctt aaaaaatctg ctgttctctc aacttctgcc cttgcagatt ttatgtcttt
     6361 ggctatttca agtaccagta tattagctat ctcatctata ttttctaaca ataaatcagc
     6421 agccttatga aatatattgc ctctcttgta tacaggcatt tcagcccata cttttatact
     6481 ctcttttgtg ttttttataa cctcatctac ctcatgtttt gtcatagatt gtactttccc
     6541 aacaagagaa ttatctattg gtgagtaaat ttctattggc tttctcgaat tagattctac
     6601 ccattttcca tttattaaat ttttatatac attttctttt gttttaagtt cattaaacat
     6661 atttttattc ctctctctga tataactttg tgtatttaaa ttatagccat ttattcgtta
     6721 tgtaaacatt tctttttttc ataaacgttt acctataaaa aaattttaag ttaacgtttt
     6781 tctacattct tctattttaa taacatactc gctccaaatc tatataggtc acactttaat
     6841 actaatatat caatatacca atataccaat ataccaatat accaatatac caatatacca
     6901 atataaatat tataaacata aatcacttga caaatttata agtagacaat attatatatc
     6961 tatgactcaa aatattttta aagtcatata tatcatatat agacagaaag gattgataaa
     7021 aatggctaaa agttttacag aaatagaaaa agacaatata agaaaaagac taatttcaga
     7081 atgtgaaatc aactggtcta aatatggata caaaaaaact aatattgatg aactttgttc
     7141 aaaatcagga attgcaaagg gttctttcta tacatttttt gattcaaaag aaaagttatt
     7201 ttttgaagta ttaaatggaa tccaaaacag acttatatca tcagtagatg aaattttaag
     7261 taacatgcct ccaaaagaag gctttgcaaa atccttaaaa atgttatatc gattatatga
     7321 taaaaatcca tttttatatt caccaaataa tcctgatttc atcagcctaa taaataaact
     7381 acctcaagat atgtttttac aacttgagtc caataacata caaagttttt acgacttaat
     7441 tgagagacac aatctcaagt tgaagataga aaaagaaaaa gtttttggtg tttgtaatgc
     7501 tctactatca agtctgttgg taaaagaaaa tattgaatat aactatattg aagtgtttga
     7561 ctttatggtg gataatcttg tagaacacat acttgaataa caatttaaaa taatttttct
     7621 aagtattttt ttatactaaa taggattaat atgattgaat taatgcaaaa aataaacaat
     7681 ataatttata aaataaatga taaactaaat atcacacaaa acttatagac cctagagcaa
     7741 acccattcca ctctactcta agccatctat aatagtttgt atatttctaa taatattaga
     7801 tattaaagta agaaaaaaat tccttataat aattgctatt atatcaatta ttgtaaatgt
     7861 tttaataatc ttagataggt aggtacatat atggtaaaat cctcgaacac ttttaataaa
     7921 aacttcaact tgatgatatt aggtcaaata atctcattgt ttggtgcatc aatacttaaa
     7981 tttgctttat ctttatacat acttgatata actggtaaag cagaaatatt tgctactata
     8041 ctagcagtat cttcaatccc aattatagta ttctccccta ttggtggagc tattgcagat
     8101 atattcaaca gaagaaactt aatggttatt tttgattttt caagtagtct tacagtacta
     8161 atcttagcag tattcttatt caacaataat ggttcaatat tacttgtagg aattattatg
     8221 accatattat cagtcataag cacaatgtat caaccaactg ttcagtcaag tacacccctt
     8281 ttagttgata atgagcattt aatgaatgca aatggtattg tagctggagt tgcatctctt
     8341 acaaatattg caggacctgt attaggaggt gtcttgtatg gtgtgattgg aattaatgca
     8401 attatagtta taagttgtgt aagtttcttt ctatctgcaa ttatggagat atttatacag
     8461 attcctttta tcaaacaaga gcaaaacagc aacattataa aaactatatt tactgatata
     8521 aaggatggta ttgttcatat atgtaaagaa aatagattta tactaaaaat acttttttta
     8581 gctatagcaa taaacttatt tttaagctct atgttaatag ttggtatccc ctatatagta
     8641 aaaatcacta tgggagctag taacttctta tatggtctag cagaaggagc aatttctttt
     8701 agttcactgg tagctgctgt tagtattggt attttctcaa aacatctaaa aatcactaat
     8761 ttgcatattt cctttattat atgtgcagtt atgttcatac caatggcggt ttcagtatat
     8821 ccatttatat taaacacagg atttccagtt ccatttttaa tctttatagt atcatctatg
     8881 ctaatatttt ttacaacgac tcttatctca atatatgtta taacagtcac acaattaaaa
     8941 actccaaatg aactcttagg aaaagtaatg tcaattcttt ttgcaggaac agcaattgca
     9001 atgccccttg gtcaggttat gtatggtaaa ctttttgatt tattatcaga tagagtgtac
     9061 atcattatac taggagttgg atttattaca ttacttatag catttgtatc aaagataaca
     9121 ttgaggaacg aaaatcttta gatacaaaga atttagatat aaagatttaa ttttcactaa
     9181 tttctgaatt taaatgcaaa attgtgtatc agtatgttga cgttttagaa attgattgat
     9241 ataatcaatg gaaaataaac tttataaaaa ttcaaaatat tcagctagag gagtgataaa
     9301 aatgagttac atgccaactt tagaacaagc atgggaaata ttaagaaaat acaataagga
     9361 agaatttcat ataagacatg ctcaaattgt atctggagtt atgagatact atgcaaagga
     9421 gtacgaccct gaaagagtag aattttggga aatagttgga cttttacatg atttagattt
     9481 tgaaatgtat cctgatgaac attgtgttaa acaaagagaa ttaatgacag agcttgattt
     9541 agataaatca ataatcgatt ctacaataag tcatggatat ggattaactg gttcagatgt
     9601 taaaccagag caatttatgg agaaagtatt atttgctgtg gatgaactta ctggtttaat
     9661 tggtgctgct gcaataatgc gtccttcaaa gagcgtttct gatttagaat taaaatctgt
     9721 taagaagaaa tttaaagata aatcatttgc tgctggctgt tctcgagacg ttataagaag
     9781 tggtgcagaa atgcttggat gggaacttga taagcttatc caaacaacta tagaagctat
     9841 gagaagcttg attccagaga tggcaatata gctcctccat acatatacca tagaagttac
     9901 atctttaaag agcatttctc tttttgatgc aacttctttt tatattttgt agaataaaaa
     9961 gtttaatatt ttaaactcac tatataataa ataatataat gtataatagt cataaacttt
    10021 ctaaccttaa aagtttctaa taatcaataa acaattctaa tatacaaatg tcattatatg
    10081 atttaattat atatcttcaa tttatatatt aaaataaata tatatatatt aaattcttat
    10141 acaccaaatt tttacattaa acttctatgc accacattta tacatattaa attcttatat
    10201 attaaattt
//
LOCUS       DAFAZV010000083        10016 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFAZV010000083 DAFAZV010000000
VERSION     DAFAZV010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 10016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10016
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.086"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..479
                     /locus_tag="KOU88_003729"
     CDS             <1..479
                     /locus_tag="KOU88_003729"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="SAM-dependent methyltransferase"
                     /protein_id="HBK3213552.1"
                     /translation="VFEYAESYINSKKPYIEFLRIVKKHLKKNGKIIIAIENRLGLKY
                     WAGCKEDHLGTYFEGLEGYREDKGIKTFSKNELEDIFKLVGFYKYNFYYPYPDYKLPI
                     TIYSDEYLPKLGELNNNFRNFDLDRVVTFNETEVFDSIIKNNLFPIFSNSYLIILE"
     gene            498..1880
                     /locus_tag="KOU88_003730"
     CDS             498..1880
                     /locus_tag="KOU88_003730"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213553.1"
                     /translation="MSKIIYSKYSNERNKKFQIRTSILQNDDGKKIVKKLAIVDESKK
                     HIDDIFENFERLKDNYYLDERVKINLCNKTEDGLEFEYLEGMTLDKIIDDFMENNEYD
                     KSIEIIKDFRNVIFNVSTTCGFNITEDFIKVFGNVDFNSDTKATLLSNIDSSFNNLVI
                     NDAWNIIDYEWVYKFPIPIRYILYRALNIYITTSVYGSKLKDLNIYDILGYSELELSK
                     YEFMEYNFGRYIAGESISLQNLYEDIKTKKYKLEELLISNDFNKRMQIFYDEGNGFSE
                     ENSYYIDLEMKNKITIPLEKDIKSIRIDPASVNCIILINKLDVVFANETIDIKNNLIT
                     NADEKKQDLYTFLSSDPQIYIDLGNRFQKGYINFEYEIKKLDFDTYDIYLEVRNLMLN
                     NQNKLINLNKELEERNMQLDILGKEINQINDRLENTLNELDNAKNKIYILEKRKIKNI
                     LRNMKKRISK"
     gene            1914..3074
                     /locus_tag="KOU88_003731"
     CDS             1914..3074
                     /locus_tag="KOU88_003731"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213554.1"
                     /translation="MHFFTSITTNYLPKARVLANSVKKNCENSWFILVVCDNLPNDFN
                     LEKEPFDEVWTIESLGLPVENLNMWIFQHTVVELCTAVKGQAMLNLLNKYEKCVYLDP
                     DMVVFDSLKELENLLDSHDIILTPHVTHKEEEEQHIRNNEIASLRYGAYNLGFLAVKR
                     NENGLEFVTWWRDRLCKYCFDDIPGGLFTDQKWIDLAPGLFEGVYILRDPSYNVATWN
                     ITWRKISNLDGKYKVNNIDLKIYHFSGFDSGAQEIMLKVNGGNNQALWNLREQYILEQ
                     EKNGQKELGSLKGKFDTFDNGEIISKDMRVLMRNRLDLQDYFKEKNPFCSVGEKSYYN
                     WYKNNVSFRLDDETLDEKSKKILELENELNRLRKMISPLQQIKKILKKFLKR"
     gene            3085..6633
                     /locus_tag="KOU88_003732"
     CDS             3085..6633
                     /locus_tag="KOU88_003732"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012744.1,HMM:NF025665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HBK3213555.1"
                     /translation="MNNRDKNILFLIHDYIKYDTPMNVGGTQLHIEDLISKIENETFY
                     ILYKKKNKLILDEYRDSKLINTYNYYCGDLSSVVEYTNPLFKLIYSAILVNFKIDLIH
                     IHHLKNHTFDIIYEAKSLNLPIIITIHDYYLVCPKINLIDRNNCCCVNRETKELCGEC
                     MSEEIGMSFEELHLYREEVSKILLMCNEVIIPNKSVSEVLLIHYYCIKEKIRVIEHGQ
                     TGEVSKYAPTYKNGKFNVAFVGGLKPCKGSKEIIKIIKNCTDKDINFFVFGTIDDKDF
                     DDIPSHNINCTGNYFRKDIYKLLEENEIHIVCILSIWPETFCYTLSESWQCNIPVITV
                     DIGATGERVKNGGGILITGNNIGESTLKSIIELKNDRNKYESLCKTVKNIKLRDIGEM
                     SKDYSNLYFSYMKNVMLDNKISSELILDALKNIDLFQTNNSIKNYELEDLKNEIKYIK
                     GTFAYRVWQKYKDMKIPFKSNISSFFKRKVSLEKDISKNKNIIKRKSEQLNIISNIEY
                     EQVYYENEKLNFYVEGWFFSKYYDMNVSCENCESFSIERLSRPDVQSHFGGKKEAENS
                     GYRIAFIGVEENSKISLVFDIGNLKKYYNFNVDTSQGVVYIGKYPKKLRWKSIPQLFD
                     MTVVEPYKYKKVIDKNSETIENVSLILNATRPIKKEWAEETIRSIINQGFKSLYIISC
                     NENLNLFSEIDNIMLVSSKLLTRKEECLEFLTSKYDFNCEYVSFISIGDKMEVNTIRE
                     MIKEAKKSNSFIVTTNENRFFEEEYFAPFYKQQLYNRFDNPSIDRLCRKSMLISTDKI
                     IDFISGNIKSNEIKIIDKILYNYRLYNDNIDNKVKVLAYYLPQFHTIPENDEWWGEGF
                     TEWVNVNRGRPMFKGHYQPHVPGELGYYNLVKDEGIQKKQSQLANDYNIYGMCYYYYW
                     FNGKKLLEKPLENLIADKSINTNFCICWANENWCRRWDGLENEILIKQEHNVQSDKRF
                     IYDVLPILKDERYITIDNKPILLVYKSDLFPNFISTVESWNKICIENGLEGLEVITVQ
                     TGGLEDPRNMGCKYAVEFPPHNIYSRVLSAKSKVEELDKDFEGTILDYSEVAGIGMNK
                     KAQPYTFFRGVMLSWDNTARRNTQSRIFYGSNPNEYKKWIASVIDFSINFYEEKERMI
                     FINAWNEWAEGTHLEPDEKYGHKYLEVTKEVLGAQY"
     gene            6811..8181
                     /locus_tag="KOU88_003733"
     CDS             6811..8181
                     /locus_tag="KOU88_003733"
                     /inference="COORDINATES: protein motif:HMM:NF025665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 99-like
                     domain-containing protein"
                     /protein_id="HBK3213556.1"
                     /translation="MNKLNSLIKRLYHMLPLSYEKKILLKNNVYKLLSPFIKNTNMYS
                     IWINSLENPEKYIKDNNPKKGVDNEKDIYIDNLFKRASEKSSNYIEISDTRFQLEKND
                     IKLISFYLPQFHPIVENDEWWGRGFTEWTNVSKAVPQFLNHYQPHLPAELGFYDLRLK
                     EVMKRQIELAKMYGIYGFCFHHYWFAGKRLLERPVNMLLKDKELDIPFCLCWANENWT
                     RRWDGLENEVLIEQKHSKEDDLEFIKDISNYFKDERYIKIDGKPVLIIYRIELLPNPI
                     ETIKLWRKYCLEIGWNDIFIVGAQTFGFEEHIKYGMDAGVEFPPHNINNCPILNKEIN
                     FTNKKFTGLVYDYKKLVDDKLYIKKSHGKVFKTVMPSWDNTARKPNNASIFKNSTPEL
                     YKKWLKDIIYSTKENVLDSDNFIFINAWNEWGEGAHLEPDRKYGYSYLNATREAIIET
                     RSEKNN"
     gene            8222..>10016
                     /locus_tag="KOU88_003734"
     CDS             8222..>10016
                     /locus_tag="KOU88_003734"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213557.1"
                     /translation="MDKLKKNNNLKIKIIFFILLQIFFIFFLVVNFKTPLLGEDYALL
                     YNGPFKDIGDYFSTIMAALEKQMSTWMVRMGNPLTIIWLSFDKSIYNIAVSFVSMIFF
                     FLIFFYGNARKPNVNNLGDLIGFFVPASLMMFLSPSIGDLFFWCNGSLNYLWPLCILL
                     LCAIPYRLYLSEKNINIKNPILIILYCIACFISGFTNENTPPVIITLVAALIIRDLYL
                     KKKPPKWIVFSFISICAGWIGLVVNSTTRFRSMYYRNMFGLPEHATINELINNVLRVG
                     YLFLKSGFAFVIIFLILSLLFIFILKSQKTENEFKYKHLFAENMFFILLTFISAAALV
                     FAPYTELRSFTLIHTIILATISNLLVNLYEISSHKQRLGLSSISIITLLSTFLLFINI
                     YNEYNDYYKFDTQRTCDIKSQVAAGKTTVYASKNFIENRTMNNREFYIYGNDLGQGGN
                     FYSDYFGAKKIIWYDKIDSNIDPATINLSSESTDVNVELINGNSEQDNSSLLSDGIFN
                     VSGWAIDKVAGNSPSKVFIKIDDKYYQARTVIREDVAKYFDNKKYKKAGFECSIPTKD
                     IKKGKHKVTLCVISNDGEKRYEVDSGKSIEFK"
BASE COUNT         4080 a          916 c         1660 g         3360 t
ORIGIN      
        1 gagtatttga gtatgcagag agttatatta attctaaaaa accatatatt gaatttctta
       61 gaatagtaaa gaagcatcta aagaaaaatg gtaaaattat tattgcaata gaaaataggt
      121 taggattaaa atattgggct ggatgcaaag aagatcattt aggaacatat tttgaaggtt
      181 tagaaggata tagagaagat aaaggtataa aaaccttctc taaaaatgaa cttgaagata
      241 tatttaagtt agttggtttt tataagtaca acttttatta tccatatcca gactacaaat
      301 taccaataac aatctattca gatgaatatc tacctaaatt aggagaactt aataataatt
      361 ttagaaattt tgatttagat agagtagtta catttaatga aactgaagta tttgattcta
      421 ttattaagaa taacttattt cctatttttt caaattctta tttaataata ttagaataaa
      481 aggaagtgaa aatccagatg agtaaaatta tttacagtaa atattcaaat gaaagaaata
      541 aaaaatttca aataaggaca agtatattac aaaatgatga tggaaaaaaa attgtaaaaa
      601 aattggctat tgtagatgaa tctaaaaaac atattgatga tatttttgag aactttgaga
      661 gattaaagga taattattat ctggatgaaa gagtaaaaat aaatctatgt aataagactg
      721 aggatggttt agagtttgag tatttggaag gtatgacatt agacaaaata atagatgatt
      781 ttatggaaaa taatgaatat gataagtcta tagaaattat taaagatttt agaaatgtca
      841 tttttaatgt gagtactact tgtggtttta atattactga agattttata aaagtatttg
      901 gtaatgtaga tttcaattct gacacaaagg ccacactatt aagcaacata gattcttcct
      961 ttaataatct tgttattaat gatgcttgga atataattga ttatgaatgg gtatataaat
     1021 tccctatacc aataagatat attttataca gagctttaaa tatttatata actacatcag
     1081 tttatggaag taagctaaaa gatttaaata tttatgacat attaggatat agtgagttag
     1141 aattatctaa gtatgagttt atggaatata attttggacg ttatattgct ggtgaatcta
     1201 tatcattaca aaatttatat gaagatataa aaacaaaaaa gtataagtta gaagagttat
     1261 tgattagtaa tgattttaat aaaaggatgc aaatattcta tgatgaaggc aatggcttta
     1321 gtgaagaaaa ctcatattac attgatttag aaatgaagaa taaaattaca attccattag
     1381 aaaaagatat taaatctatt agaatagacc ctgcttctgt taattgtatt attcttataa
     1441 ataaattgga tgtagttttt gcaaatgaaa ctatagatat aaaaaataat ttaattacta
     1501 atgcagatga aaaaaaacag gatttatata cttttcttag cagtgaccct caaatatata
     1561 tagacttagg gaataggttt caaaaaggct atataaactt tgaatatgag attaaaaaac
     1621 ttgattttga tacatatgat atttatttag aggtcagaaa tttaatgtta aataatcaaa
     1681 ataagttaat aaatctaaac aaagaacttg aagaaagaaa tatgcaatta gatatactag
     1741 gtaaagaaat caatcaaata aatgatagat tagaaaatac actaaatgaa ctggataatg
     1801 caaaaaataa aatttatata ttagagaaaa gaaaaataaa gaatatattg agaaatatga
     1861 aaaaaagaat tagtaaataa ttattttatt tcaaaagaag gagtattaaa aatatgcatt
     1921 tttttacaag tattactaca aactatttgc caaaagctag agtattagca aattctgtaa
     1981 agaagaattg tgaaaactca tggtttattt tagttgtatg tgataatcta ccaaatgatt
     2041 ttaatttgga gaaagaacct tttgatgagg tttggactat tgagagttta ggactacctg
     2101 ttgaaaattt aaatatgtgg atttttcaac atacagtagt agaattgtgt actgccgtca
     2161 aagggcaagc catgcttaat ttattaaata aatacgaaaa gtgtgtgtat ttagatcctg
     2221 atatggtagt atttgatagt ttgaaggaac ttgaaaatct tttagacagt catgatataa
     2281 tattaacacc acatgtaact cataaagaag aagaagaaca acatattcgt aataatgaaa
     2341 ttgcatcact acgttatggt gcatataatt taggattttt ggctgtaaaa agaaatgaaa
     2401 atggtttaga gtttgttaca tggtggagag atagactttg taaatattgc tttgatgata
     2461 taccaggagg actttttact gaccaaaaat ggatagatct tgcaccaggg ctatttgagg
     2521 gggtatatat attacgagat ccttcatata atgtagctac ttggaatatt acatggagaa
     2581 aaatcagtaa tttggatgga aaatacaaag ttaataacat tgatttaaaa atatatcact
     2641 tttcaggttt tgattctgga gcacaagaga taatgttgaa agtaaatgga ggaaataatc
     2701 aagcgttatg gaatctaaga gaacagtata ttttagaaca agaaaagaat ggtcaaaaag
     2761 agttaggaag tttaaaaggt aaatttgata catttgataa tggagaaatc atatcaaaag
     2821 atatgagagt attgatgaga aatagattag atttacaaga ttattttaag gaaaagaatc
     2881 cattctgctc tgttggagaa aaaagttatt ataattggta taaaaataat gtatctttta
     2941 ggcttgatga tgaaacttta gatgaaaaaa gtaaaaaaat tttagaactt gaaaatgaac
     3001 taaatcggct aagaaaaatg ataagcccac tacaacaaat aaaaaaaatc ttgaaaaaat
     3061 ttttaaagag ataggaggaa aatcttgaat aatagagata aaaatatttt gtttttgata
     3121 catgattaca taaaatatga tactcctatg aatgtaggcg gaacccagtt acatatagaa
     3181 gatttaattt caaaaataga aaatgagaca ttttatattt tatataagaa aaaaaataaa
     3241 ttaatcttag atgaatatag agattcaaag ttaataaata catataatta ttattgtgga
     3301 gatttatctt cagtagtaga atacacaaat ccgttattta aacttatata ctctgctata
     3361 cttgtcaact tcaaaataga tttgattcat atacatcatt taaaaaatca cacatttgat
     3421 ataatatatg aagctaaaag tttaaactta ccaattatta ttactataca tgattattat
     3481 ttagtatgcc ctaagattaa tctgattgat agaaataatt gttgttgcgt aaatagagag
     3541 actaaagaac tctgtggaga atgtatgtct gaagaaatag gtatgtcatt tgaagaacta
     3601 catttgtata gagaggaagt aagtaaaata ttattgatgt gcaatgaggt tattatacca
     3661 aataaatctg ttagtgaagt acttttaatt cactattatt gcataaaaga aaagataaga
     3721 gtaatagaac atggacaaac aggtgaagta tctaaatacg cacctacata taaaaatgga
     3781 aagtttaatg ttgcatttgt aggaggattg aaaccatgca aaggtagtaa agaaattata
     3841 aaaataatta aaaattgtac tgataaagat attaattttt ttgtatttgg gacaatagat
     3901 gataaagatt ttgatgatat tccaagtcat aatataaatt gtacaggaaa ctattttaga
     3961 aaagatatat ataaattatt agaagaaaat gaaatacaca ttgtttgtat attatcaatt
     4021 tggcctgaaa ctttttgtta cactttaagt gaatcttggc aatgtaatat acctgtgatt
     4081 acagttgata ttggagctac aggagagaga gtgaaaaatg gtggaggtat tttaattact
     4141 ggaaataata ttggagaaag tactctaaaa tcaattatag agttaaagaa tgatagaaat
     4201 aaatatgaaa gtttgtgtaa gacagttaaa aacataaaac tacgagatat tggagaaatg
     4261 tctaaagatt attctaacct atattttagt tatatgaaaa atgttatgtt agataataaa
     4321 atttcttcag agctaatatt agatgcttta aaaaatatag atttatttca aacaaataac
     4381 agtattaaaa attatgaact tgaagatcta aaaaatgaaa ttaagtatat aaaaggtact
     4441 tttgcctatc gtgtttggca aaaatacaag gatatgaaga taccttttaa gagtaatata
     4501 tctagtttct ttaaaagaaa agtatcttta gaaaaagata tatcaaaaaa taaaaatatt
     4561 ataaaaagaa agtctgaaca attgaatata atatcaaata ttgaatatga acaagtttat
     4621 tatgaaaatg aaaagttaaa cttttatgtt gaaggttggt ttttcagtaa atattatgat
     4681 atgaatgtat cttgcgaaaa ttgtgaaagt tttagtatag aaaggttaag tagaccagat
     4741 gtacaatctc attttggtgg gaaaaaagaa gctgaaaata gtggatatag aattgctttt
     4801 ataggggtag aggaaaatag caaaatatca ctggtttttg atataggtaa tttgaagaaa
     4861 tattataatt ttaatgttga tacttcacag ggagttgtat atattggaaa atatcctaaa
     4921 aaacttagat ggaagagtat accacaatta tttgatatga cagtagtaga gccttataag
     4981 tataaaaagg taatagataa aaatagtgaa acaattgaaa atgtttctct gatattaaat
     5041 gcaactcgtc caataaaaaa agagtgggct gaagaaacca ttagaagtat aataaatcaa
     5101 ggatttaaat ccttatatat aatttcttgt aatgaaaatt taaacttatt ttcagaaata
     5161 gataatatta tgctagtgag ttctaaattg ttaaccagaa aagaagagtg tttggagttc
     5221 ttaactagta aatatgattt taattgtgag tatgtttctt ttatatctat tggggataag
     5281 atggaagtta atacaattag agaaatgata aaggaagcaa aaaaaagtaa tagttttata
     5341 gtaactacaa atgaaaatag attttttgaa gaagaatatt ttgctccatt ttacaaacaa
     5401 caactttata atagatttga caatccatca atagatagat tatgtagaaa gagtatgtta
     5461 atttctactg ataaaataat tgattttatt agtggaaata taaaaagtaa tgagattaag
     5521 attattgaca agatattgta taattataga ttatataatg ataacataga taataaagta
     5581 aaagtattgg catattattt accacaattt catactattc ctgaaaatga tgagtggtgg
     5641 ggagagggat ttacagaatg ggtaaatgta aatcgtggac gacctatgtt caaaggtcat
     5701 tatcaaccac atgttccagg ggagttaggc tattacaatt tagtaaaaga tgaaggaatt
     5761 cagaagaagc aatctcagct agcaaatgat tataatatat atggaatgtg ctattattac
     5821 tattggttta atggtaaaaa attattggag aaaccgttag aaaatcttat agctgataag
     5881 agtataaata caaatttttg tatttgttgg gcaaatgaaa attggtgtag aagatgggat
     5941 ggacttgaaa atgaaatact tataaaacaa gaacataatg ttcagagtga taaaagattt
     6001 atttatgatg tattaccgat actaaaggat gaacgttata taactataga taacaaaccg
     6061 attttactag tttataagtc agacttattc ccaaatttta tatcaactgt tgaaagttgg
     6121 aataaaattt gtatagagaa tggtctagag ggtctagaag taattactgt tcaaactgga
     6181 ggtctagagg atccaagaaa catgggctgt aaatatgcag ttgaatttcc accacataat
     6241 atttattcaa gagtcttatc tgcaaaatca aaggtagaag aattagataa agattttgaa
     6301 ggaactatat tagactatag tgaggttgca ggcataggaa tgaataaaaa agctcagcca
     6361 tatacatttt ttagaggtgt aatgctaagt tgggataata cagcacgacg aaatacacaa
     6421 tctcgtattt tttatggctc aaatccaaat gaatataaaa aatggattgc atccgtaatt
     6481 gacttttcaa taaattttta tgaagaaaaa gaacgtatga tttttataaa tgcatggaat
     6541 gagtgggctg aaggcacaca tttagaacca gatgaaaaat atggacataa atatttagaa
     6601 gtgacaaagg aagttttagg agcacaatat tagtagatac ctttaataaa taggttttta
     6661 aatcaaaata tatagtttta ctataattag aagttgtaga ttataatctc ttaatacaat
     6721 ttgtatagaa attgtgttaa gaggttattt acatgctaat cacctattaa tgttttctga
     6781 gttaattaaa attttcaagg aggtatttta ttgaataaac taaatagttt aattaaaaga
     6841 ttatatcaca tgttaccatt gagttatgaa aaaaaaattc tgttaaaaaa taatgtgtat
     6901 aaactattat ctccatttat aaaaaataca aatatgtata gcatttggat taatagttta
     6961 gaaaatccag aaaaatatat aaaagataat aacccaaaga agggtgtaga taatgaaaaa
     7021 gatatttata tagataattt atttaaacga gcttcagaga aatctagtaa ctatattgaa
     7081 ataagtgata caaggtttca attagaaaaa aatgatataa agctgatatc tttttattta
     7141 ccacagtttc atccaattgt agaaaatgat gaatggtggg gaagaggatt tacagaatgg
     7201 acaaatgtga gtaaagcagt tcctcaattt ttaaatcatt atcaaccaca tctaccagca
     7261 gaattgggtt tttatgacct gagattaaaa gaagttatga agagacaaat agagttagca
     7321 aaaatgtatg ggatatatgg tttttgtttt catcattatt ggtttgcagg taaaagactt
     7381 ttagagagac cagtaaatat gttattaaaa gataaagaat tagatattcc cttttgtcta
     7441 tgttgggcaa atgaaaattg gacaaggcgt tgggatggtt tggaaaatga agttttaata
     7501 gaacaaaagc actcaaaaga agacgattta gaatttatta aagatataag taattatttt
     7561 aaagatgaga gatatataaa aattgatgga aagccagttt tgattattta tagaatagaa
     7621 ttattaccaa atccaataga aacaataaaa ttgtggagaa aatattgcct agaaattggc
     7681 tggaatgata tattcattgt gggagcacaa acatttggat ttgaagaaca cattaaatat
     7741 ggaatggatg caggtgttga atttcctcct cataatataa ataattgtcc tatattaaat
     7801 aaggaaataa attttacaaa taaaaaattt actggtttag tttacgatta taaaaaatta
     7861 gttgatgata aattatatat aaaaaaatca catggaaagg tatttaaaac tgtgatgcct
     7921 tcttgggata atacagctag aaagccaaat aatgcaagta tatttaaaaa ttctacacca
     7981 gagttatata aaaaatggtt aaaagatatt atatattcta caaaagaaaa tgttttagat
     8041 agtgataact ttatatttat aaatgcttgg aatgaatggg gagaaggtgc acatcttgaa
     8101 ccagatagaa aatatggcta ctcatactta aatgcaacaa gagaagctat aatagagact
     8161 aggagtgaga aaaataatta aaaattagtt atttaaatag atgtttaagg agagttaaaa
     8221 tatggataag ttaaaaaaaa ataataacct aaaaattaaa ataatatttt ttatattatt
     8281 acaaatattt tttatatttt ttttagttgt aaatttcaaa actcctcttt tgggagaaga
     8341 ttatgcttta ctatataatg gtccatttaa agatataggt gactattttt cgacaattat
     8401 ggcagctctt gaaaagcaga tgtcaacttg gatggttaga atgggaaatc cattaacaat
     8461 aatatggcta agctttgata aaagcatata taacatagca gtttcatttg tatcaatgat
     8521 tttctttttt cttatatttt tttatggaaa tgcaagaaaa ccaaatgtga ataatctggg
     8581 tgatttaata ggtttttttg ttccagcatc acttatgatg tttttgagtc cttctatagg
     8641 ggatttgttt ttttggtgca atggcagtct taattattta tggcctcttt gtatattact
     8701 tttgtgtgca attccttata gactttattt atcagagaag aacataaata ttaagaatcc
     8761 tattttgatt attttatatt gtatagcttg ctttatatct ggttttacaa atgaaaatac
     8821 tccaccagtt attataacat tagtagctgc attgataata agagatttgt atttaaaaaa
     8881 gaaaccacct aaatggatag ttttttcctt tatatctatt tgtgcagggt ggataggatt
     8941 agtagtgaat tcaaccacca gatttagaag tatgtattat aggaatatgt ttggcttacc
     9001 agaacatgct actataaatg aacttataaa taatgtttta agagtaggat atttattctt
     9061 gaaaagtgga tttgcatttg taattatatt tttaatttta agtttgttat ttatatttat
     9121 attaaagtct caaaaaactg aaaatgagtt taaatataag catttgtttg cagaaaatat
     9181 gttttttatt ttattaactt ttatctctgc agcagcatta gtttttgcac catatacaga
     9241 acttagatca tttacactta ttcatacaat catattagca acaataagta atttattagt
     9301 aaatttatat gaaatatcta gtcataaaca aagacttgga ctgagtagta ttagtataat
     9361 tactttactt tctacttttt tactttttat taacatatac aatgaatata atgactatta
     9421 taaatttgat actcaacgta cttgtgatat aaagtcacaa gtagcagctg ggaaaactac
     9481 agtatatgct tcaaaaaatt ttattgaaaa tcgtactatg aataatagag aattttatat
     9541 ctacggaaat gatttaggac aaggtggaaa tttttactca gattactttg gagctaaaaa
     9601 aataatctgg tatgataaaa ttgatagtaa tatagatcca gctactatta atttatcaag
     9661 tgaatctaca gatgtgaatg tagaacttat aaatggaaac tctgaacaag acaatagttc
     9721 tctattatct gatgggattt ttaatgtttc tggttgggca atagataagg tggctggaaa
     9781 ctctccaagt aaagtattta taaaaataga cgataagtat tatcaagcta gaacagtaat
     9841 acgtgaagat gttgctaaat attttgacaa taaaaagtat aaaaaagcag ggtttgagtg
     9901 ttctatacca actaaagata taaaaaaagg gaagcataaa gtgacacttt gtgtcataag
     9961 taatgatgga gaaaaaagat atgaagtaga ttcaggaaaa tctatagaat ttaaat
//
LOCUS       DAFAZV010000084         9496 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFAZV010000084 DAFAZV010000000
VERSION     DAFAZV010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9496)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9496)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9496
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.087"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(69..2288)
                     /locus_tag="KOU88_003735"
     CDS             complement(69..2288)
                     /locus_tag="KOU88_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBK3213558.1"
                     /translation="MININYREDQIPIINYDNGTMAVPAVPGAGKTFIITNLVAKLLL
                     EQKHKGGKILILTYMNSAVNNFKGRIRKILEENKIDDTNSYEVMTIHSLAVKIIKEKP
                     EVVMLSEDFNIADDLQKSIILNECISRFRFEGGERAFRWFLKEQKDERWKEITLEAWE
                     RGFFEFAGNAISELKYKGISPDKLEEILSRGHKGMLKIILPIYKLYDRKLKQNGLLDY
                     DDILILAEKTLSLDEGLRKKFQTRYKYIFEDECQDSNEIQGNIIKIISSENKNLVRVG
                     DINQSITGTFSSSDPKFFKEFINSADFCYRMDMSNRSSKDILDLANTLVKYVTKEFRQ
                     KECRHALEDMQIKTVPNGMGYKENPNPEHYNINVKWYESWKIEIEQTARYVKGIKNKY
                     PDKSIGILVPFNEQVTQVAKELRENNLTFEELGPNSLNKRKVINNIAYIIDFMLHCDD
                     VEKLIVVLNKVFIDTDNEEEIKYFLEELKNYSTEEIIYNFEFSKLDNDLIEFKEESDI
                     YLSFKRGIDIIKQILEYPIIRLDLLVLFIGKKLNLEKEDKAVLDYISFYIKYLVSENI
                     NMDLEDVYNLLFDVKNRVFNHIIDVVYEINGYEPEPGSITLCNYHKSKGMEWDCVFLL
                     GLVEYNFPDNINQKFQSDKWYLKEKYKNPMAIIKSEVEAILKGSISTDYAHKTKIDSI
                     NEKIRLLYVGITRAKEMLVLSGSAYRDESDIGNKRKEQKPCIYLSRLNQHIIEKRSN"
     gene            complement(2281..4194)
                     /locus_tag="KOU88_003736"
     CDS             complement(2281..4194)
                     /locus_tag="KOU88_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213559.1"
                     /translation="MEYLFEKSSLKEYGNEALDKYRELLDKTGNNSRCILLLVPNNNT
                     KIRYERALRLNYSEELKITTYISFVKKELVKYWPLIIEKCDEISTKVVSPTFISNSLS
                     EYLIVQKVKEKRIQEGYFEDITGTNKSIANSIMTNINKSAFNLIDFDFIGEKIYSSKK
                     NKDSIYRFSYTQMDEIISYYINSLLSNSILDNALSIYLYNQYLLNDDFYLKNLFTEVR
                     YIIVDSLESSSNAEVDFITEALDNTLQSYIYFDYSRDYSVFNNVDIDYINEKIISKIK
                     PKEENIKKKEIRVEDLYLLPANIELNQSSQLYNEMLDLISEKVISLIEEDVSPRDIAI
                     ISPINNSILEHQIRDSLIEKNIDVFSTKKDKKAVDYPYGNALVVATCIFYGYLDFIKD
                     DEYLSFLETLLEINRIKAFKIFNETRHLSIDNIDEHSQYRDILQYIEEKKKSDIKIHE
                     FLTQFYIDKMLNLKEGKKNVGLCKKIIAESESFSESLSLLGMKKEKIFVEALKSTIND
                     YYSVVDIEELKSKDKIVITTPYSYISSNIDRSIQIWVDIGSNAWNMKIEKDISNLIVL
                     RKSFEEKKIYTNEIEEYYKKYYLYNTVYNLLLNAKKIYAFKSEYAINGYIQDSILYSI
                     LLKISHKGDKNYD"
     gene            complement(4422..6434)
                     /locus_tag="KOU88_003737"
     CDS             complement(4422..6434)
                     /locus_tag="KOU88_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3213560.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLNTTLNYNQSTGAYEGTINYNQDPE
                     YLNVWELQGITINSKNNPKTLNRQDLEKLGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSSPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPKDIIIIGDENAISKTTANQIKSTVNASQTRLNGSNRY
                     ETSLLIAKEIDKNHDVEKIYITNANGGEVDALTIAAKAGQDKQPIILTDKDSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNGITKDSVTNNRVYGADRHETNANVIKKFY
                     TDNELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMSSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSAPGNSSGGMIEKD
                     YNLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLKPDLFTSIHYNGSTNK
                     QGHGVEVFYKLKDKNGGTTKTVATNILNRILEKFKLTNRGIKTRVLPSDSTKDYLYVL
                     RSNDMPAVLVECAFLDNENDMSLINSSAKVKEMGTQIGKGIEDSLK"
     gene            complement(6939..8957)
                     /locus_tag="KOU88_003738"
     CDS             complement(6939..8957)
                     /locus_tag="KOU88_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3213561.1"
                     /translation="MRRNTKLLTTGILSMAIVAPTMAFATESNAMENNADLNINLEKK
                     SIVLGSKSKVSVKFKEKPDADSITLKYKCYDMPLDTTLNYNQSTESYEGTINYNKDPE
                     YLNVWELQGITINSKNNPKTLNKQELEKMGLNLKDYNVTQECIIEDITSRKDVNKYLR
                     KTSAPITELTGSDRYETAVKISKEGWKNGSDKVVIINGDVSIDGIISTPLATTYNAPI
                     LLVEKNNVPNSVKSELKRLNPRDVIIIGDENAISKTTANQIKSTVNASQTRLKGSNRY
                     ETSLLIAKEIDKNHDVEKVYITNANGGEVDALTIAAKAGQDKQPIILTDKNSITDNTY
                     KWLKSEDLQNAYFIGGPQMISTNVINKVNDITKDNVTNNRVYGADRHETNANVIKKFY
                     TDDELEAVLVAKSDVLVDALAAGPLAANLKSPILITPKTYVSAYHKDNLEAKSANKVY
                     KIGGGLTSKVMNSIASSLSKHNTTPTEPGNSGGKTVMIDPGHGGSDTGTTGKPLGGIK
                     EKDYTLNTSLATTEYLRSKGFNVIMTRDTDKTLSLGNRTALSNSLRPDLFTSIHYNAS
                     DTTGNGVEVFYKLKDKDGGTTKTVATNILNRILEKFNLKNRGAKTRTLSTDPKKDYLY
                     VLRNNDMPAVLVECAFLDNEKDMSLLNTSNKVKEMGTQIGKGIEDSLK"
     gene            complement(9231..9347)
                     /gene="rrf"
                     /locus_tag="KOU88_003739"
     rRNA            complement(9231..9347)
                     /gene="rrf"
                     /locus_tag="KOU88_003739"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(9356..9429)
                     /locus_tag="KOU88_003740"
     tRNA            complement(9356..9429)
                     /locus_tag="KOU88_003740"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(9395..9397),aa:Gly,seq:tcc)
BASE COUNT         2912 a         1591 c          996 g         3997 t
ORIGIN      
        1 ttactgtaca tattgtttta tcccctttta gatatatttc aagcaatctt ttaataactt
       61 attatatatt aatttgacct tttttcaata atatgttgat taagtctgct taaatatata
      121 catggttttt gctcttttct cttattccct atatcacttt catctctata agcacttcct
      181 gaaagtacta acatttcctt tgctctagta atccctacat ataaaagtct aatcttttca
      241 tttatagaat caatcttcgt tttatgagca taatctgttg aaatacttcc ttttaatata
      301 gcttcaactt ctgatttaat aattgccata gggtttttat atttttcttt tagataccat
      361 ttatcactct gaaacttttg attaatattg tcagggaaat tatattcaac aagacctagt
      421 aaaaacacac aatcccattc catccccttt gatttatgat agttacatag tgttatacta
      481 ccgggctctg gttcatatcc atttatctca tataccacat ctattatatg attaaacacc
      541 ctgttcttta catcaaacaa taaattatat acatcttcta aatccatatt tatattttct
      601 gatactagat actttatata aaaagatata taatccagta cagctttatc ttctttttct
      661 aaattaagtt ttttcccaat aaacaaaact aagaggtcta accttattat tggatattct
      721 aatatctgtt ttataatatc tattcctctt ttaaaactta aatatatgtc actttcttct
      781 ttaaattcta ttaaatcatt atctaactta ctaaattcaa aattataaat aatttcttca
      841 gtagaatagt tttttaattc ttctaaaaaa tactttattt cttcttcatt atcagtatct
      901 ataaaaactt tattaagtac aactattaac ttttctacat catcacaatg taacataaaa
      961 tcaataatat atgctatgtt gtttataacc ttccttttat tcaaagaatt tggtcctaat
     1021 tcttcaaaag ttagattatt ctctctaagt tctttagcaa cttgtgtcac ttgttcatta
     1081 aatggaacca atatacctat acttttatct ggatatttat tttttatacc tttaacatat
     1141 ctagcagttt gctctatttc aattttccaa ctctcatacc actttacatt tatattataa
     1201 tgttctggat taggattttc tttatatccc attccatttg gcacagtttt tatttgcata
     1261 tcttcaagag catgtctaca ttctttctgt ctaaattcct ttgtaacata cttgacaaga
     1321 gtgtttgcta aatcaagtat atcttttgaa cttcgatttg acatatccat cctataacag
     1381 aaatctgcac tatttataaa ttctttaaaa aatttagggt ctgatgatga aaatgttcct
     1441 gttatactct gatttatatc tccaactcta actaggtttt tattttcgct agatataatt
     1501 tttattatat taccttgaat ttcatttgag tcctgacact catcttcaaa tatatatttg
     1561 tatctagttt gaaacttctt tctaagccct tcgtctaagc ttaaagtttt ttctgctaaa
     1621 attaatatat catcataatc tagcaatcca ttttgcttta attttctatc atacaattta
     1681 tatattggta aaataatttt aagcattcct ttgtgtcctc ttgacaatat ttcttcaagt
     1741 ttatctggag aaattccctt atacttaagt tcacttattg catttcctgc aaattcaaaa
     1801 aaacctcttt cccaggcttc aagagttatt tctttccagc gttcatcttt ttgctccttt
     1861 aaaaaccatc taaaagctct ttctccacct tcaaatctaa atctacttat acattcattt
     1921 aatataatac ttttttgcaa atcatcagct atattaaaat cctcacttaa cattacaact
     1981 tctggctttt cctttattat ttttacagcc aaactgtgta tagtcattac ttcatacgaa
     2041 ttagtatcat ctattttatt ctcttcaaga atctttctta ttctaccttt aaaattattt
     2101 acagcactat tcatatatgt aagaattaat attttaccac ccttatgttt ctgttcaagt
     2161 aatagtttag caactaaatt tgttattata aatgtttttc cagcacctgg tactgctggt
     2221 actgccatag taccattatc gtaatttatt attggtatct ggtcttctct ataatttata
     2281 ttaatcataa tttttatctc ctttatgtga gatttttaaa agtatactat ataatatact
     2341 atcttggata taaccattaa tcgcatattc acttttaaat gcatagattt tctttgcatt
     2401 taataacaaa ttatatactg tattgtatag atagtatttt ttataatatt cttctatttc
     2461 atttgtataa atcttttttt cttcaaaaga ttttctaagt acaattaaat tacttatatc
     2521 tttttctatt ttcatattcc aagcattact tcctatatct acccatattt gtatacttct
     2581 atctatattt gatgatatat atgaataagg agtagttatt actattttgt ctttggattt
     2641 caactcttct atatcgacaa cagagtaata atcgtttatt gtacttttta aagcttctac
     2701 aaatatcttt tcttttttca tcccaagtag acttaaactt tcactaaaag actcactttc
     2761 agctattatc tttttacata acccaacatt ctttttacct tcttttaaat ttaacatttt
     2821 atctatgtaa aattgagtta aaaattcatg tatttttata tcactcttct ttttttcttc
     2881 aatatactgt aaaatatcac gatactgact atgttcatct atattatcaa tacttaaatg
     2941 tcttgtttca ttaaaaatct taaatgcttt tatcctattt atttctaaaa gagtttctaa
     3001 aaagcttaag tattcatcat cttttataaa atctaaatat ccatagaata tacatgtagc
     3061 cactaccaat gcattcccat atggataatc cacagctttt ttatccttct tagtactaaa
     3121 aacatctata tttttttcta tcaaagaatc tctaatttga tgctccaata tactattgtt
     3181 tataggagat ataattgcta tatctcttgg agatacatct tcttctataa gagatataac
     3241 tttttcactt attaaatcta acatttcatt atataattga cttgattgat ttaattctat
     3301 atttgcaggt aataagtata aatcttctac tctaatctcc ttctttttaa tattttcttc
     3361 tttaggctta atttttgata ttattttctc atttatatag tctatatcca cattattaaa
     3421 tacagaataa tccctactat aatcaaaata tatataactt tgtaatgtat tatccaatgc
     3481 ttctgttata aaatcaactt ctgcattact tgagctttca aggctatcca caattatata
     3541 tctcacttct gtaaataagt tttttaaata aaaatcatca ttaagtaggt attgattgta
     3601 taaatatatg cttagtgcat tatctaaaat tgaatttgat agtaaggaat ttatataata
     3661 tgatataatt tcatccattt gagtgtatga aaatctatat atactatctt tatttttctt
     3721 tgatgaatat attttttctc caataaaatc aaaatcaatt aaattaaatg cagacttatt
     3781 tatgttagtc attatactat ttgctatgga tttattggtt cctgtaatat cttcaaaata
     3841 tccttcttgt atcctttttt ccttaacttt ttgcactatt aaatattcac ttaaactatt
     3901 tgatataaat gttggagata caacctttgt acttatttca tcacattttt ctattattag
     3961 tggccagtat ttaactaatt ctttcttcac aaaacttata tatgttgtta ttttcagttc
     4021 ttcactataa tttaatctta gagccctttc atatcgtatc tttgtgttat tgtttggtac
     4081 taacaaaaga atacaccttg aattattacc agttttatct aataattctc tatatttatc
     4141 taaagcttca tttccatatt cttttaaact acttttttca aataaatatt ccatataatc
     4201 accttcctca attaaattaa gtgtatatta tctaattata tcatattgtg tattttacaa
     4261 aacacaatca aattattgca tttaactaca aaaaaagact gtatatatac ttgcattcac
     4321 atgtgcaaat gtacatacag tcttactatt gatacactta tatttcattt tttgacttta
     4381 gtataaattt acattaagtt tttaaatatt tttatttcca tttattttaa tgaatcttct
     4441 attcctttac ctatttgtgt acccatttct tttacttttg cagatgagtt tattaaactc
     4501 atatcatttt cattatccaa aaatgcacat tctacaagta cagctggcat atcattactt
     4561 cttaaaacgt ataaataatc ttttgtagaa tcactaggaa gtactcttgt ttttatacct
     4621 ctatttgtaa gtttaaattt ctctaaaatt ctatttaata tattggtagc tacagtttta
     4681 gtagtccctc catttttatc tttaagctta taaaatactt ctacaccatg accttgttta
     4741 ttagttgagc cattataatg tatacttgta aataaatctg gtttcaatga attagataga
     4801 gcagttctat ttccaagaga taaagtctta tctgtgtctc ttgtcattat tacattgaat
     4861 ccctttgaac gtaaatattc agttgttgca agtgaagtat ttaaattgta atctttttca
     4921 atcattcctc cagatgaatt tccaggtgct gaaccaccat gccctgggtc aatcataact
     4981 gtcttgcccc cactatttcc tggttctgtt ggagtcgtat tgtgtttaga taatgatgat
     5041 gctatagagc tcattacctt agaagtcaat cctcctccta ttttgtatac cttattagct
     5101 gatttagctt ctaaattatc tttatggtat gcagatacat acgtctttgg tgttataagt
     5161 attggagatt ttaagttcgc agccaatgga cctgctgcta aagcatcaac aagtacatct
     5221 gatttagcta ctaaaacagc ctctaactca ttatctgtat agaatttttt tattacgttt
     5281 gcatttgttt cgtgtctatc tgctccgtat actctattat tagtaacact atctttagtt
     5341 attccattta ccttatttat aacatttgtt gatatcattt gaggaccacc tataaaataa
     5401 gcattttgta aatcctcact ctttaaccat ttatatgtat tgtctgtaat actatcttta
     5461 tcagttaata taattggttg cttgtcttga cctgcttttg ctgctatagt aagtgcatcc
     5521 acttctccgc cattagcatt tgttatgtat attttttcca catcatgatt tttatctatt
     5581 tcctttgcta tcaataaaga tgtctcatat ctattagaac catttaaacg tgtttgacta
     5641 gcatttacag ttgatttaat ttgattagca gtagttttag aaatagcatt ctcatctcca
     5701 attataatta tatctttagg gtttaggcgc tttaattctg attttacact attaggtaca
     5761 ttgttttttt caaccaaaag tattggtgca ttatatgtgg ttgccagtgg agttgatata
     5821 atgccatcta tacttacatc cccatttatt ataactacct tatctgaacc atttttccag
     5881 ccctctttac ttattttaac tgctgtttca tatctatcac ttcctgtaag ttctgtaata
     5941 ggtgaagaag tttttctcaa atatttattt acatcttttc tagaagttat atcttcaatt
     6001 atacattcct gtgttacatt atagtctttt aaatttaatc ccagcttttc taggtcttgt
     6061 ctgtttaaag ttttaggatt atttttgctg tttattgtta tcccttgtag ttcccaaaca
     6121 tttagatatt ctgggtcttg gttataattg atagttcctt catatgcccc agttgattga
     6181 ttgtaattta gagttgtatt caatggcatg tcatagcatt tatactttaa tgtaatgcta
     6241 tctgcatctg gtttttcttt aaatttgaca ctaacttttg atttgctacc taaaacgata
     6301 ctttttttct ctaagtttat atttaaatca gcgttatttt ccatagcatt agattcagta
     6361 gcaaatgcca ttgtaggtgc gacgattgcc attgaaagaa tccctgttgt taataatttt
     6421 gtatttcttc tcatattaat ctccttactt aacataaatt tctactttat ttttaatctt
     6481 ttaacttttg aaaatatgtc aaagtgtatc taacccaaaa tataaataat atataagtaa
     6541 tatataaaaa taaacttata aaactcaaaa aataaaaaaa ttaaatatat ttaatacatt
     6601 taattatcta tactatatca tttattgaca taaaaatcca caaaaaacac acaaacacac
     6661 aataaaatat agtaattaag cttatattgt gtattacaaa tgaatactcc aactcttaac
     6721 aattaactgt agccttaaga tatgtaaatt cttcatataa tataaatcct tttacaatta
     6781 atcataaaaa gactgtatat acctcatttc gcacttatat gcacaatgta tatacagtct
     6841 ttattactat tataattaca ttcttatctt atagctttag tttaaattta aaattgcaga
     6901 ttaatttatt ttaaattttt ctatgctctc attgtagact attttaatga atcttctatg
     6961 cctttaccta tttgtgtacc catttctttt actttatttg atgtattaag taaactcata
     7021 tctttctcat tatccaaaaa tgcacattct acaagtacag ctggcatatc attatttctt
     7081 aaaacatata aataatcttt tttagggtca gttgatagtg ttcttgtttt tgcacctcta
     7141 ttttttagat taaatttctc taaaattcta tttaatatat ttgtagctac agtcttagta
     7201 gttcctccat ctttatcttt aagcttataa aatacttcta caccattccc agttgtatca
     7261 gatgcattat agtgtatact cgtaaataaa tctggtctca aagagttaga taaagcagtt
     7321 ctatttccaa gagataaagt cttatctgta tctcttgtca ttattacatt gaatcccttt
     7381 gaacgtaaat attcagttgt cgcaagtgaa gtatttaatg tatagtcttt ttctttaata
     7441 ccccctaatg gtttacctgt tgttccagtg tccgaaccac catgtcctgg gtcaatcata
     7501 actgtcttac ccccactatt tcctggttct gttggagttg tattgtgttt agataatgat
     7561 gatgctatag agttcattac cttagaagtc aatcctcctc ctattttata tactttatta
     7621 gctgatttag cttctaaatt atctttatgg tatgcagata catacgtctt tggtgttata
     7681 agtattggag attttaagtt ggcagccaat ggacctgctg ctaaagcatc aacaagtaca
     7741 tctgatttag ctactaaaac agcctctaac tcatcatctg tatagaattt ttttattacg
     7801 tttgcatttg tttcgtgtct atctgctcca tatactctat tattagtaac attatcttta
     7861 gttatatcat ttaccttatt tataacattt gttgatatca tttgagggcc acctataaaa
     7921 taagcatttt gtaaatcctc actctttaac catttatatg tattgtctgt aatactattt
     7981 ttatcagtta atataattgg ttgcttgtct tgacctgctt ttgctgctat agtaagtgca
     8041 tccacttctc cgccattagc atttgttatg tatacttttt ccacatcatg atttttatct
     8101 atttcctttg ctatcaataa agatgtctca tatctattag agccctttag acgtgtttga
     8161 ctagcattta cagtcgattt aatttgatta gcagtagttt tagaaatagc attctcatct
     8221 ccaattataa ttacatccct aggatttaaa cgctttaatt ctgattttac actattaggt
     8281 acattgtttt tttcaaccaa aagtattggc gcattatatg tagttgctag tggagttgat
     8341 ataatgccat ctatacttac atccccattt attataacta ccttatctga accatttttc
     8401 cagccttctt tacttatttt aactgctgtt tcgtatctat cacttcctgt aagttctgta
     8461 ataggtgcag aagtttttct taaatattta tttacatctt ttctagaagt tatatcttca
     8521 attatacatt cctgcgttac attatagtct tttaaattta atcccatctt ttctagttct
     8581 tgtttgttta aagttttagg attatttttg ctgtttattg ttatcccttg tagttcccaa
     8641 acatttaaat attctgggtc tttattataa ttgatagttc cttcatatga ctcagttgat
     8701 tgattataat ttagagttgt atccaatggc atatcatagc atttatactt taatgtaatg
     8761 ctatctgcat ctggtttttc tttaaactta acactgactt ttgatttgct acctaaaacg
     8821 atactttttt tctctaagtt tatatttaaa tcagcgttat tttccatagc attagattca
     8881 gtagcaaatg ccattgtagg tgcgacgatt gccattgaaa gaatccctgt tgttaataat
     8941 tttgtatttc ttctcatatt aatctcctta tttaacataa atttctactt tgttttttaa
     9001 ccttttaatt tttgaaatta tatcaaagtg tttttaccca aaattataaa taagtacata
     9061 aaaaataaac ttctaaaaaa attataaaaa caaaaaataa aaaaattaaa tatattgaat
     9121 atatttaatt atcttcacta tatcatttat tgccaaaaaa atctataaaa gacaaataaa
     9181 aacatataat aattgtaggt ttattaaatt taatacaaca aaaaaagatt acgtggctac
     9241 gtcctactct cccaggcagt ttcccaccaa gtaccatcag cgctagagag cttaacttct
     9301 gtgttcggaa tgggaacagg tgtatcctct ctgctattgt aaccacataa tcttttggag
     9361 cgggtgaagg ggatcgaacc ctcacagctg gcttggaagg ccagaactct accattgagc
     9421 tacacccgca ttaaattttt ataaattagt aaaactaatt ttttagagtt agcactctaa
     9481 aaactacata tatatc
//
LOCUS       DAFAZV010000085         9433 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFAZV010000085 DAFAZV010000000
VERSION     DAFAZV010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 9433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9433
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.088"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            442..1647
                     /locus_tag="KOU88_003741"
     CDS             442..1647
                     /locus_tag="KOU88_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBK3213562.1"
                     /translation="MSKKVLIMSASTGGGHNRAALAIKEELTSKTLDGEPIECEIIDS
                     LKLVNNTMDKIISRGYEKSAIYTPKAYGSVYRLSETNLLSKNEFKDNLLITFMAKKFK
                     KLIRSEKPDLIIGTHPFPMIALSTLKKNFNLHNNESNAYTEHFYKHYTNTINVPPLIS
                     VLTDYTTHSTWIQNEIDYYIVGHEYVKELLVFDGVEPSKIRTFGIPVEKSFLSHRDKD
                     IVLSELNLSPDKLTVLLMGGSFGAGNIKETLDELLDTNRDFQILVITGKNESLKEKIE
                     KKLMSRYHDKNVCVLGYTDKMNDILASIDVLVSKPGGLTTTEALLKDVPMIVPYYIPG
                     QEEENLDFLSNCGAALRTTKKYNLSILLKVLIDDPSRLEMLKRNIKSIRKSNSAQNIA
                     NLILNIISG"
     gene            complement(1718..1939)
                     /locus_tag="KOU88_003742"
     CDS             complement(1718..1939)
                     /locus_tag="KOU88_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213563.1"
                     /translation="MKPIMNLEEHNAMKEKRVKKMKSKDKPKYDDFEDISFSNKKKTK
                     KNVRNKNAEFRNNYKNYQYDYEEDFYEPI"
     gene            complement(2080..2679)
                     /gene="recR"
                     /locus_tag="KOU88_003743"
     CDS             complement(2080..2679)
                     /gene="recR"
                     /locus_tag="KOU88_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012634696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBK3213564.1"
                     /translation="MQVYTGPITRLIEEFSKLPGVGRKTAQRLAFHIINMNTNDVEAL
                     SKAIIDAKREIRYCSICCNITDTDPCSMCSNKSRDSSVICVVEDPRDVAAMERTREFK
                     GQYHVLNGVISPMDGIGPDMLKIKELIQRLGNQEVKEIIMATNPTIEGEATAMYIARL
                     VKPMGIKVTRIAHGLPVGGDLEYADEVTISKALEGRREI"
     gene            complement(2692..3042)
                     /locus_tag="KOU88_003744"
     CDS             complement(2692..3042)
                     /locus_tag="KOU88_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009887752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBK3213565.1"
                     /translation="MAKKGFGGGMMPGGGNMNNLLKQAQKMQENMQKAQQELESKEVE
                     ASVGGGAVTVKVNGKKEVIDITIKPEVVDPDDIEMLQDLVLSAVNQALRNIDDIQASQ
                     MSKVTGGMNIPGLF"
     gene            complement(3101..4738)
                     /gene="dnaX"
                     /locus_tag="KOU88_003745"
     CDS             complement(3101..4738)
                     /gene="dnaX"
                     /locus_tag="KOU88_003745"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBK3213566.1"
                     /translation="MHKALYRAYRPQKFEDVIGQDHIIKTLKNQIYSDNIGHAYLFCG
                     TRGTGKTSTAKIFSRAVNCLNKINEEPCNECEICESVLKDNTMDVVEIDAASNNSVDD
                     IRELRESVKYSPANAKYKVYIIDEVHMLSQGAFNALLKTLEEPPSYVIFILATTEPHK
                     IPATILSRCQRYDFKRVTVKDMTLRMKKICEDEGIDIDDKALNLIARNSQGALRDALS
                     ILDQCMSFGESKIDYKDVVELMGSVNIEQLFELSQCIVEQDTKKSLEILNEFVLWGKD
                     IRNLINDLIDHFRNLMVCKVSSELDEIISLPEETIEQLKIQSKNIDINDLIRILNILS
                     ITQDDIKSSSNPRVLVEITIMKIAQPMFDESKEALIKRVENLEKMIELGNFKSEKIGN
                     NKEKEYEVDREIDVKQENVVYEDVKNEDVILIESSWKNILKQIKKDKKMPIYALLSEV
                     KSFNVYSNMLYVIFDDKFDFAKTRLSSQDTINYLEKTIRDVLNRSFNVKIVLTSEVKD
                     INLEVKEKKDIGEEILKNIVSEEILEIKDSIDENESK"
     gene            complement(4815..5079)
                     /gene="ffs"
                     /locus_tag="KOU88_003746"
     ncRNA           complement(4815..5079)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="KOU88_003746"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            complement(5117..5208)
                     /locus_tag="KOU88_003747"
     tRNA            complement(5117..5208)
                     /locus_tag="KOU88_003747"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5172..5174),aa:Ser,seq:gga)
     gene            complement(5209..5664)
                     /locus_tag="KOU88_003748"
     CDS             complement(5209..5664)
                     /locus_tag="KOU88_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HBK3213567.1"
                     /translation="MESSFYMKEALKEAYKAYNKKETPIGAIIVKDNQIIARAHNLTE
                     TLKDSTAHAEILAIKQASEKLGGWRLTDCDLYVTMEPCIMCSGAIVNSRIKKLIIGTR
                     HVKNSYIEKQHEFKLDYFNNNNVKVAFDVLQEECSIILQEFFKALRKRD"
     gene            complement(5985..7256)
                     /gene="serS"
                     /locus_tag="KOU88_003749"
     CDS             complement(5985..7256)
                     /gene="serS"
                     /locus_tag="KOU88_003749"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBK3213568.1"
                     /translation="MLDIKRIRENLDDIKKAMERRGEREFDLDAVVELDNKRREILQE
                     VEVMKNELNVNSKKIPQLIKEGKDVTEEKARLKELSDKIKGIDEKVKEVEAKMEYTLM
                     RIPNVPHPEVPQGETDEDNVQIRTWGEPTKFDFEHKAHWDIGTGLGILDFERAGKITG
                     SRFTLYRGLGARLERSLMNFFLNTHTAKHGYTEVLPPFMANRNSFIGTGQLPKFEEDM
                     FKIEGLEYFLIPTAEVPVTNIHANEILDVAELPIKYCAYTPCFRSEAGSAGRDTRGLV
                     RQHQFNKVELVKFVKPEDSYNELESLTHDAETMLQMLGLPYRVVKICTGDLGFTAAFK
                     YDLEVWMPSYNRYVEISSCSNFEDFQARRAGIRFKRDKKSKAEYVHTLNGSGLAIGRC
                     LAAILENYQQADGSVVVPEELRPYMGVDVIK"
     misc_binding    complement(7382..7587)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(7715..8596)
                     /locus_tag="KOU88_003750"
     CDS             complement(7715..8596)
                     /locus_tag="KOU88_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HBK3213569.1"
                     /translation="MNFLSLAKTASTNSNITKRTLENMLDNFSDNIPNIIYAIIVFVI
                     GIYISKIVRRMVSKFLIKYGMSKGVNNFIVYGIYISMLSIISLISLGIIGIQTTSVVA
                     VLGAAGFSIGLAFKEILSNLGSGMIILFFKPFNIGDYIQGSGVEGTVSDIQIFSTVLK
                     TPDNKTIIIPNFQLTSNNIINYTHQNKRRIDFSYNISYDSDIDVVKSILNEIFTNEKR
                     ILNDPKPIIGLNSIGNNTMQIVARPWVKTDDYWDVYFDVMEKVKNKFDENDIKVPFVP
                     SSLLFNNTGNLNTMDKR"
     gene            complement(8608..9117)
                     /locus_tag="KOU88_003751"
     CDS             complement(8608..9117)
                     /locus_tag="KOU88_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003421631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBK3213570.1"
                     /translation="MNSNERRSKLIDILKESKHPVKGGTLAELLNVSRQVIVQDIALI
                     RARGFEIIATPQGYIIYNQPYFTKQIKCKNHKDSKEIYDELKIIVDLGGIIKDVIVNH
                     PTYGQITAELNVYSKMDIDNFMKKVETNEFKQLSVLTECSHIHTIEAIKEETIEAIVK
                     ELKDNGILS"
     gene            complement(9244..9360)
                     /gene="rrf"
                     /locus_tag="KOU88_003752"
     rRNA            complement(9244..9360)
                     /gene="rrf"
                     /locus_tag="KOU88_003752"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         3012 a         1645 c         1006 g         3770 t
ORIGIN      
        1 atataaatta acctactgtt taattttcaa tgttcgtgtt tatttctttt tccttttttc
       61 aaggacaagt aatactatat catctttatc tattctagtc aatataattt tttacttttt
      121 ttaatttttt tatttatcat gtattcttta tctttaattt ttaaaactta atgctaagta
      181 aacctgttta tttcataaaa ctaatatata ttctatgctc tattttcctt tttattctat
      241 atttaaattt tttatttaca agaatatttt taatataaca tatttgataa aattaattta
      301 catttctttc acttgtaatt tttgcaatct tgtattagat taatattaaa aataatttat
      361 caataacctt attcacaaag acagttttta tatatcaaaa tataatataa atactatgct
      421 acattttagg aggattttat tatgagcaaa aaagtattaa taatgtctgc ttccactggt
      481 ggtgggcata atagggctgc tctagctatt aaagaagaac ttacttccaa aacacttgat
      541 ggagagccaa ttgaatgtga aataatagat agtttgaaat tagttaataa tacaatggat
      601 aaaataattt caagaggata cgaaaaatct gctatatata ctcccaaagc ctatggaagt
      661 gtatatagat tatctgaaac aaatcttttg tcaaaaaatg aatttaaaga taatctacta
      721 ataacattca tggctaaaaa atttaaaaag cttattagaa gcgaaaaacc agacttgatt
      781 ataggaacgc atccttttcc aatgattgct ctaagtacat tgaaaaaaaa ctttaattta
      841 cataataatg aatcaaatgc ttacacagag catttttata aacattatac aaataccatt
      901 aatgttcctc cgcttatttc tgtattaact gattatacta ctcattctac atggatacaa
      961 aatgaaattg attactatat tgttggtcat gaatatgtaa aagaattatt ggtgtttgat
     1021 ggagttgaac cgagtaaaat tagaacattt ggaatccctg ttgaaaaatc ttttctctct
     1081 cacagagata aagatattgt tctttctgag ttgaatttat ctcctgataa attaactgtt
     1141 ttacttatgg ggggtagctt tggggctgga aatataaaag agacacttga tgaattactg
     1201 gatactaata gagactttca aatacttgta attactggta agaatgaaag cctaaaagaa
     1261 aaaatcgaaa aaaaacttat gtctcgttat catgataaaa atgtatgtgt tcttggatac
     1321 actgataaga tgaatgatat tttagcttct atagatgtat tagtaagcaa acctggtgga
     1381 cttactacaa ctgaggctct tttaaaagat gtacctatga tagttcctta ttatatacca
     1441 ggtcaggaag aagagaatct tgatttctta tctaattgtg gtgcagcact tagaactaca
     1501 aaaaaatata acttgtcaat attactaaaa gttttaatag atgaccctag cagattagaa
     1561 atgctaaaaa gaaatattaa atcaataaga aagtcaaatt cagcccaaaa tatagctaat
     1621 ttaattttaa atataatttc tggttgataa aataaataaa atccctatag tatatatatt
     1681 atctattagg gattttttat tttctaatta tttaatatta aattggttca taaaagtctt
     1741 cttcataatc atactgataa tttttataat tatttctaaa ttcagcattt ttatttcgta
     1801 catttttttt agtttttttc ttattagaaa aacttatatc ctcaaaatca tcatatttag
     1861 gtttatcttt tgatttcatt tttttaactc ttttttcttt cattgcatta tgttcttcta
     1921 agttcataat tggtttcatg ttgcacccct atcaaaattt ttaaatgatt tatacaacaa
     1981 attatacaat acagaagaaa tttattcaat aaatctaaat caaaattaat ttgaatttaa
     2041 ctcaaaaaat tacaaaaatc gaggtattaa cctcgatttt tatatttctc ttctgccttc
     2101 tagtgctttt gatattgtga cctcatctgc atactctaaa tcgcctccaa caggaagacc
     2161 atgagctatc cgagtgactt tgattcccat tggttttact aacctagcaa tatacatggc
     2221 tgtagcttca ccttcaatag taggatttgt tgccattatt atttctttga cttcctgatt
     2281 gccaagtctt tggataagtt cctttatttt taacatatct ggtccaattc catccattgg
     2341 agaaattact ccatttaata catgatactg tcctttaaac tctctcgttc tctccatagc
     2401 tgctacatct cttggatctt ccacaacaca tataacactt gaatctctac ttttatttga
     2461 acacatgcta catgggtctg tatctgttat attacaacaa attgagcaat atcttatttc
     2521 tctttttgca tctataatcg ctttagataa agcttccaca tcattagtat tcatattaat
     2581 aatatgaaaa gccaatcttt gagcagtctt tcttcctact ccaggaagct ttgaaaattc
     2641 ctctataagt ctcgttatgg gacctgtata aacttgcata aataccacct actagaataa
     2701 cccaggtata ttcatacctc cagttacctt actcatttga cttgcttgta tatcatcaat
     2761 atttctcaat gcttgattta ctgcacttaa aactaaatct tgtagcattt ctatatcatc
     2821 tggatcaact acttctggct tgatagttat atctataact tcttttttac cattaacttt
     2881 tacagtaact gctcctccac caactgaagc ttctacttct ttactttcta actcttgttg
     2941 agctttttgc atattttctt gcattttttg agcctgcttt aacaagttgt tcatatttcc
     3001 accaccaggc atcattccgc ctccaaaacc ttttttagcc ataaacacta ttcctcctaa
     3061 acttattttc attttattat tatatcataa tagtatttta ttatttactc tcattttcat
     3121 caatactatc ttttatttct aatatctctt cactcactat gttctttaat atttcctcac
     3181 caatgtcctt tttctcttta acttcaagat ttatatcttt aacttctgat gtcagtacta
     3241 tttttacatt aaaacttcta tttaaaacat ctcttattgt tttttctaaa taatttattg
     3301 tatcttgaga gctcagtcta gtttttgcaa aatcaaattt atcatcaaat ataacataca
     3361 acatattaga atatacatta aaacttttta cttcacttaa gagtgcgtat attggcattt
     3421 ttttatcttt tttaatttgt ttaagtatat tcttccaaga tgactctata agtataacgt
     3481 cctcattttt tacatcttca taaactacat tttcttgttt tacatctatt tctctatcga
     3541 cctcatactc tttttcttta ttattcccaa ttttttcaga cttaaagttc cccagttcaa
     3601 tcattttttc taagttctca actcttttta taagagcttc tttactttca tcaaacattg
     3661 gttgagcaat tttcattatg gttatttcca ctaaaaccct tggatttgaa gatgacttta
     3721 tatcatcctg agttattgat aatatattta aaatccttat taaatcattt atatctatat
     3781 ttttagactg aattttaagt tgttctatag tttcttctgg taatgaaatt atttcatcca
     3841 attctgatga aaccttacat accattaaat ttctaaaatg atcaattaag tcatttataa
     3901 gatttcttat atctttgccc cataagacaa attcatttaa tatctcaaga gactttttag
     3961 tgtcctgctc tacaatacat tgagacaatt caaataattg ttctatattt acgcttccca
     4021 ttaattcaac aacatcttta taatctatct tactttctcc aaaagacata cattggtcta
     4081 atatactaag tgcatctcta agagctcctt gagaatttct agctattaaa ttaagagctt
     4141 tatcatctat atcaattcct tcatcttcac aaatcttttt cattctaagg gtcatatctt
     4201 taactgtaac tcttttaaaa tcgtatcttt ggcatcttga taaaatggtt gcaggtattt
     4261 tgtgaggctc tgtagttgct aatataaaaa ttacatatga tggaggttcc tctaaggtct
     4321 ttaataatgc attaaaagct ccttgagaca acatatgaac ttcatctatt atatatactt
     4381 tatatttagc attggctgga gaatatttca cactttctct aagctctctt atatcatcta
     4441 cactattatt tgaagctgca tctatttcta caacatccat tgtattatct tttaacacag
     4501 attcgcatat ctcacactca ttacacggtt cttcatttat tttattcaaa cagtttactg
     4561 ctcttgaaaa aatctttgca gtagatgttt taccagtacc tcttgttcca caaaacaaat
     4621 aagcatgtcc tatattatca ctatatattt gattctttaa agtcttaata atatgatctt
     4681 gaccaataac atcttcaaat ttttgtggtc tatatgctct atataatgct ttatgcatct
     4741 ttttacctct ctttagcaaa attaataaaa aaatccctca ttatctaagg gattagtctt
     4801 ttatatatta aatgctgtac accatctatc gacttaattc cataggcgtt atcaaaacag
     4861 ttagctcaac ttaggcaccc ccacggcaca caaaagtgat cacttaccgc tgcttccttc
     4921 cggatctgac ggggttcatg agctttcatt gcgcaggacc taagcatcaa caccacttat
     4981 ttagggcggc cctacagaaa ataagccttt agatggaatt caatcctgct atagcggatt
     5041 gcaggttaca gggcaccgct acctccccat ctagtacagc aaaattacaa ccatatttaa
     5101 ttactttcat tgtttctggc ggagagagtg ggatttgaac ccacgataca gttttaccca
     5161 tatactcgct ttccaggcga gcgccttcga ccactcgacc atctctcctt aatctctttt
     5221 tctcaatgcc ttaaaaaatt cttgcaatat gatcgagcat tcttcttgca aaacatcaaa
     5281 agctactttt acattattat tattaaaata atctaattta aactcatgct gtttttctat
     5341 atatgaattt tttacatgtc ttgtccctat tataagcttt tttattctag aattaactat
     5401 tgcgccacta cacattatgc aaggttccat tgtaacatat aaatcacaat cagtcaacct
     5461 ccaaccacct aatttttctg atgcttgttt tatcgctaaa atttctgcat gtgccgtaga
     5521 gtcttttaac gtttctgtaa ggttatgagc tctagctatt atttgattat ctttaactat
     5581 aatagcacct attggtgttt cttttttatt atatgcttta tatgcttctt ttaatgcttc
     5641 tttcatataa aatgaacttt ccataattcc tcccaaaact tataacaaac ttatcttatc
     5701 ataattcatt ttataattca acttaatttt attttgttta tttaattatt actatatata
     5761 gctatatttt tttaaaatta gttctaaaat aatttttaga tattcataca aaagtgtttt
     5821 ataaaaatat ttagtgtttt atgatgaaaa ttctgctgtg taaattaaca taaaaaaact
     5881 atgaaattaa tatttataat aatttcatag tttttttatt tattgtttac tcataatata
     5941 ttctcttcat caaagcatac tctacatata caattaatat aaatttattt tataacatca
     6001 acacccatat aaggtcttaa ttcttctgga actactacag aaccatctgc ctgctgataa
     6061 ttttctaata tagcagccaa acatcttcct attgctaatc cagaaccatt taatgtatga
     6121 acatattctg cttttgattt tttatctctt ttaaatctta ttcctgctct tcttgcttgg
     6181 aaatcttcaa aatttgaaca agaagatatt tctacatatc tattgtaact tggcatccaa
     6241 acttctaaat catatttaaa tgcagctgta aatcccaaat ctcctgtaca tatttttaca
     6301 actctatatg gaagacctaa catttgtaac atagtttcag catcatgagt taatgattct
     6361 aattcattat aagaatcttc tggtttaaca aatttaacta attcaacttt attaaattga
     6421 tgttgtctaa ctaaacctct tgtatctctt cctgctgaac ctgcttcaga tctaaaacaa
     6481 ggagtatatg cacagtattt aattggaagc tctgcaacat ctaatatttc attagcatgt
     6541 atattagtaa caggaacttc agctgttggt attaagaaat actctaatcc ttctatttta
     6601 aacatatctt cttcaaattt aggaagttga ccagtcccta taaaactatt tctattggcc
     6661 ataaatggag gtaagacttc cgtatagcca tgcttagctg tatgagtatt taaaaagaaa
     6721 ttcattaaag atctttctaa tctagctcct aatcctctat ataaagtaaa ccttgaccca
     6781 gttattttcc ctgctctttc aaaatctaaa atacctagac ctgtacctat atcccaatgc
     6841 gctttatgct caaaatcaaa tttagtaggt tctccccaag ttcttatttg aacattgtct
     6901 tcatctgttt caccttgtgg tacctctgga tgaggaacat ttggtattct cattaatgta
     6961 tattccattt ttgcttctac ttcttttact ttctcatcaa taccttttat cttatctgat
     7021 aactctttca atcttgcctt ttcttctgtt acatcttttc cttcttttat taattgaggt
     7081 atttttttag aatttacatt taactcattt ttcataactt caacttcttg aagtatttct
     7141 cttcttttat tatctaattc cactacagca tcaaggtcaa attctctttc acctcttctt
     7201 tccatagctt ttttgatatc atctagattt tctcttattc ttttaatatc taacatatta
     7261 attcctccta ataattttga taatataagt tataattcca acttaattta caaacattat
     7321 acttgtaaac tcttagttta aacaaatttt aaaaataaaa aaagacctcc gtttacccta
     7381 taaaagggac gaaaatcttt tatccgcgtt gccaccctaa ttgactatac taaaatgtat
     7441 aatcctctca gacctataac gtaggtaaac gtctagcttt aactagaagc tctagagtag
     7501 attcaaaaac cattgtaatg agttttcacc atccactcat tctctgaata caatctgttt
     7561 tttactattt tccttcacag ctttttaact aattgtttta tttgataatc attatattat
     7621 atatattaac atctttcaat actattattc aaattttttt agaattttct ttaatttttt
     7681 atattaaatt cattttttct atttaattaa gaccttatct tttatccatt gtatttagat
     7741 tacctgtatt attaaataat aatgaagaag gaacaaatgg aacttttata tcattctcat
     7801 caaatttatt ttttaccttt tccattacat caaaatatac atcccagtaa tcatcagttt
     7861 ttacccaagg tctagcaact atttgcatgg tgttatttcc tatagagttt aaacctatta
     7921 taggctttgg atcatttaat attctttttt cgtttgtaaa aatttcattt aatatagact
     7981 taactacatc tatatcacta tcatatgaaa tattatatga aaaatctatt cttcttttgt
     8041 tttgatgtgt gtaattaatt atattattac ttgtcagttg aaaattaggt ataattatag
     8101 ttttattatc tggcgtctta agaacagtgc taaatatttg tatgtcagaa actgtacctt
     8161 ctacacctga accttgaata taatcaccta tattaaatgg cttaaaaaat aaaataatca
     8221 taccagagcc taaatttgat aatatttctt taaaagctaa acctatacta aatccagcag
     8281 ctcctaacac agctacaact gatgtagttt gtatccctat aatacctaag cttatcaatg
     8341 atataataga taacatagat atatatattc catatacaat aaaattattt acacctttac
     8401 tcattccata tttgattaga aactttgaaa ccatccttct tactatttta gatatataaa
     8461 tacctatcac aaatacaatt attgcatata taatatttgg tatattatca ctaaaattat
     8521 cgagcatatt ttctaaagtt ctcttagtta tattgctatt tgttgaggca gtcttagcca
     8581 atgataaaaa attcattcaa ctcctcctta tgataatatt ccgttgtcct ttaactcttt
     8641 tactatagct tctatagttt cttcttttat tgcctcaatt gtatgaatat ggctacattc
     8701 tgtcagaacc gataattgtt taaattcatt tgtctcaact ttcttcataa agttgtctat
     8761 atccatttta gaataaacat taagttctgc agttatctga ccatatgttg gatgatttac
     8821 aatgacatct tttataatac cacctaaatc tacaattatc tttaattcat cataaatttc
     8881 tttagaatcc ttatgatttt tacactttat ttgttttgta aaatacggtt gattatatat
     8941 tatatatcct tgaggtgtag ctattatttc aaatcctcta gctcttataa gggctatatc
     9001 ttgaactatt acttgcctac ttacatttaa tagttcagct agtgttccac cttttacagg
     9061 atgcttagat tcttttaaaa tatctattaa tttacttctt ctttcattag aattcatatt
     9121 acaccttctt tccaaataaa aactttacct atactatata attttatatt ttatcttatt
     9181 ataaatcaat attgacttta tattctattt aatcttaact tttataataa ataaaaaaag
     9241 actacgtggc tacgtcctac tctcccaggc agtttcccac caagtaccat cagcgctaga
     9301 gagcttaact tctgtgttcg gaatgggaac aggtgtatcc tctctgctat tgtaaccaca
     9361 taatctttat gcttaatatt tctattaagt ttttaataaa tttatagaat ctagtaatac
     9421 tagtttcttt aga
//
LOCUS       DAFAZV010000086         8513 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFAZV010000086 DAFAZV010000000
VERSION     DAFAZV010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8513
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.089"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            52..435
                     /locus_tag="KOU88_003753"
     CDS             52..435
                     /locus_tag="KOU88_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213571.1"
                     /translation="MKISKLPEAELKVMRYIWEANKVLTSRELVAAMEEKYEWNESTT
                     FTVLKRLERREFLSTEKIGKLTHYNILVKEKKYLRFETKEFLKNIHKNSISSLISALH
                     SKDDEVDEDKLIELEEHFKNLKEKE"
     gene            620..1204
                     /locus_tag="KOU88_003754"
                     /pseudo
     CDS             620..1204
                     /locus_tag="KOU88_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896033.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            1230..1643
                     /locus_tag="KOU88_003755"
     CDS             1230..1643
                     /locus_tag="KOU88_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK3213572.1"
                     /translation="MKKIILASHGDFSKGLLNAVKMIVGDLADCVSSYGLYPGQSASD
                     FALELEKTISEDKECEYIILSDLYGASVCTAMLRLTNLHNVRLFSGMNLNMVLELLTR
                     FSDELTVEDIDQLVEESRRGIQSVTLQIKEEEEVF"
     gene            1647..2390
                     /locus_tag="KOU88_003756"
     CDS             1647..2390
                     /locus_tag="KOU88_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane biogenesis protein"
                     /protein_id="HBK3213573.1"
                     /translation="MKKKGILSVFKSKKPIIAMIHLKGDTPEDIFERAKKEITIFEEN
                     GVDGIMLENYYGNYYDLERILEYVSKANLSIPYGVNCLNVDTMGFELATKYNASYIQV
                     DSVVGHVKPRDEATLEEFFKLQRSKCPAYLIGGVRFKYQPVLSENDVEEDLKIGMTRC
                     DAIAVTENATGQETSMEKIELFRKNLGDFPLVIAAGVTLENAKKQLKLGDMAIIGSYF
                     KDNYKDFGDVSVEHVKTFMDEIKKIREEL"
     gene            2390..2860
                     /locus_tag="KOU88_003757"
     CDS             2390..2860
                     /locus_tag="KOU88_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK3213574.1"
                     /translation="MIKLVRVDHRLIHGQVAFTWTKFLSTDCILIASDDLLKDELRMA
                     GLKMAKPSNVKLVMKSIADSIKALNSGVTDKYNLLILCESVEDVYRLAKEVKAIKSIN
                     LGGTKSDDNRENISKAVHVSKDDIKMIKELDSEGVNVFVQLVPDDDATNVMKLI"
     gene            2877..3635
                     /locus_tag="KOU88_003758"
     CDS             2877..3635
                     /locus_tag="KOU88_003758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK3213575.1"
                     /translation="MEFTQVILITLIAFFAYMHSFVGSTMHNRPIVVAPLVGLALGNL
                     HTGIVIGSTLELVFMGAFPVGASNPPDFVSGSIIATAFVILTGQDVSAAVVLAVPIAT
                     LVLLIDNFLMTVVLTWGAHIADRYAEEGNIEGVERVQLLFGIGNKLILAIIVGIGFSL
                     GVPVIEKILSFIPSYVTHGMDVAAGVIPAIGFAMLARMMLNKKTVAFLLLGFILVAYL
                     NITVTGVALFGLAIALIYVNFVGEKEVIVDDNEF"
     gene            3619..4461
                     /locus_tag="KOU88_003759"
     CDS             3619..4461
                     /locus_tag="KOU88_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK3213576.1"
                     /translation="MTTSSKKLETISPDSKITRKDFWKCFRRSLTLDSSWNYERMQNI
                     AYAYMMAPIIRRLYKDDKEKKSKALKRHLEFMSVTPHISTLLVGISGAMEEENAKNKE
                     FDANSINAVKSSLMGPVSGIGDSFFWGTLKLIAAGVGIALASQGNIMGPILFLLIINV
                     PHFIIRYICLDKGFKYGTQFFKDVSGSSIVSKVMEAASMLGLMVIGGMTASNVMLKLS
                     VNVGSGEWAEPIQTYLDQIMPCMLPAMIFGIMYWLLGKKVKTTTILISVMIICIVLAA
                     IGVV"
     gene            complement(4621..5526)
                     /locus_tag="KOU88_003760"
     CDS             complement(4621..5526)
                     /locus_tag="KOU88_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK3213577.1"
                     /translation="MDFKQLEVFVAVAKHQSFSKAARELFLTQPTVSAHIQNLERELE
                     TVLINRSNKVITLTKSGEILYEHAIYILNNCKRAIYDIKEYSGKIEGIIDIACSSIPE
                     TYILPDFMKSFSMSYPDVKFSISHYDSQYAISEILNERISFGLVGSKINNPQIEYLDL
                     LDDELVLITPSDFKIDNKNNCIDIGELAYLNFIMRKEGSGTRNLILNTLSKNNFPVSK
                     LNVIAHVESNEAIKEMVRLGLGVSFISYISAIDYLNAGKIKCYKIKDVDFTRKFFFIY
                     SKKKTFSPLEDKFLNRLCEYFEIII"
     gene            5888..6622
                     /locus_tag="KOU88_003761"
     CDS             5888..6622
                     /locus_tag="KOU88_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213578.1"
                     /translation="MKLKRSLVCVTILGIILVGCHKENTKEKNQVASKATQQKTMTKV
                     QNDVNEIMNKDYKYIIKNMGIPYNTFYYIKPKVLKESNTMQDINTSSYMTLVYPKYTG
                     NDELDGSALYVDINENKVVNVETNSFSSQGISVIDAESSIVIEKSDHEKSAVSLENFR
                     HIDLGEYVGVEDSRINEIVGDANYDLTAYNHEGSKVVKSYRLKEDNKILKKEVLTISI
                     VDNKIKSIKTIESDKIVKIIKGTLLE"
     gene            6833..8014
                     /locus_tag="KOU88_003762"
     CDS             6833..8014
                     /locus_tag="KOU88_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBK3213579.1"
                     /translation="MIELEDAIKIIEKNVLPINRVKIVNLIDAVNKVVAEDIYSTIDS
                     PPFDRSPYDGYAYNANSENRNLKVIGTLYAGDVFNRVLNKNEAVKIMTGGKIPQGANC
                     VIKKEDVTVIGDMITLNIKLKEYDNYIFKGEDIKKGQLIINKNQNIGYDGIGVLASLG
                     ISKVTVYDDLKVGILNTGTELQDINETLENGKIYDSNRYTLYSRLLKLGIQADTICNC
                     SDDILELEKKVKNMLQSVDFLITTGGVSVGDKDLIPDVFKKIGATELFWKINIKPGGA
                     CYVGTLGEKLLFGLSGNPHAAIVVFDNVIVPVIEYLTYKKGTHHIKAIFKGEFNKLSN
                     KDRFVSGKLYTSEGKLYVELNDKKDAKARLSATLRSNCMIKIKKNETIKENQLVDVVI
                     R"
     gene            7998..>8513
                     /gene="mobB"
                     /locus_tag="KOU88_003763"
     CDS             7998..>8513
                     /gene="mobB"
                     /locus_tag="KOU88_003763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBK3213580.1"
                     /translation="MLLLDSFMKGHNFMYNILSVVSYSGVGKTTLIEGIIKELNKKGY
                     RVGVIKHTCHDFDMDEEGKDTYKHRKSGARKVCIISDKRVAYIEELKEKNPLYKMIQL
                     YEDMDLIIIEGYKNYRFKRLEVTRKGKYEDILSNKSDLIGIVSDIEYKLNIEQFNLND
                     YKNISKYIESCI"
BASE COUNT         3382 a          874 c         1502 g         2755 t
ORIGIN      
        1 ttattgatat agaatttaac atatacataa atcggtaaag gggtgtagac tatgaaaatt
       61 agtaaattac cagaagcgga attaaaagtt atgagatata tttgggaagc taacaaggta
      121 ttaacttcta gggaattagt tgctgcaatg gaagaaaaat atgaatggaa tgaatcaacg
      181 acatttacag ttttaaaaag gttagagcga agagaatttt taagcacaga gaaaataggc
      241 aaacttacac attacaatat actagtaaaa gagaaaaaat atctaaggtt tgaaacgaaa
      301 gaatttttga agaacataca taagaattca atttcaagtt taatatcagc gttacatagt
      361 aaagatgatg aagtggatga agataaatta attgaactcg aagaacattt taaaaattta
      421 aaagagaaag aataaataaa gattatttta ggtggcaaat tatttttgcc accttttttg
      481 ccaccatgac agtttaataa aataaaatac aaataaagaa atataaataa aatagaataa
      541 agaaattgtt ttagataggt tgtaaataaa tgtactcata aaaacataaa taaatataaa
      601 taaacataaa taaaatataa gaatttctgt gagaaatgca cttaatgaac ttgtaaaaga
      661 agatatatta tgtaaaaaac gtggtaaagg gacttatgta acaataccag agagaataga
      721 agcaacatgt gcaggaaata gttttactaa ttcttgtcat cgtattaatg caaaaccaag
      781 taccaaaata atctctgttt taataaaaaa agcagataag caagtagctg aagctttaag
      841 tattgaacta gaagagaagg taatatgtat taaaagactt agattaatag atgaagtacc
      901 tgttattttt gaagttgact attttagaat agattacatg tttttattaa aagaagaatt
      961 agaagataaa tctttaatgg aggttatatc taataatata agcacattac ctaaacgagt
     1021 agaaaatata tttgaagtaa aacattcaaa caaagaatat tctgaccatc ttaaatgtgc
     1081 aagtaatatg ccactattga aagtaagaca atcggtgtat acagaaaata atgatgtctt
     1141 atattacaat gagcaattta taagaagtga taagtacaaa tatgcagtat cagcagaaat
     1201 ataatctata atttagtagg aggatgagta tgaaaaagat aatattagca tctcatggag
     1261 acttttcaaa agggctttta aatgcagtaa aaatgatagt aggagattta gcagattgtg
     1321 tcagttcgta tggtttgtac cctggacaaa gtgcttcaga ttttgcttta gaattagaaa
     1381 aaacaatatc agaagataaa gaatgtgaat atataatttt atctgactta tatggagcaa
     1441 gtgtatgtac agcaatgtta agattaacta atctacataa tgttaggtta ttttctggaa
     1501 tgaatttgaa tatggtatta gaacttctta caaggttttc tgatgaatta acagttgaag
     1561 atatagacca attagtggaa gaatctagaa gaggaataca aagcgtgaca ttacaaatta
     1621 aagaagaaga agaggtattt tagtttatga aaaaaaaggg aatattatca gtatttaaaa
     1681 gtaaaaaacc aattatagca atgatacact taaaaggaga tactccagaa gatatctttg
     1741 aaagagctaa aaaagagatt acaatctttg aagaaaatgg tgtagatgga ataatgttag
     1801 aaaattacta tggtaattat tatgatttag aaagaatact tgaatatgta tcaaaagcta
     1861 atttatcaat accatatgga gtaaactgtt taaatgttga tactatggga tttgaactgg
     1921 caacaaaata taatgctagt tatatacagg ttgattctgt agtaggtcat gttaaaccta
     1981 gagatgaagc tactttagaa gagtttttta aattacaacg ttcaaaatgc ccagcgtatt
     2041 taattggagg cgtacgtttt aaatatcagc cagtattatc agaaaatgat gttgaagaag
     2101 atttaaaaat aggaatgaca agatgtgatg ctatagcagt tacagaaaat gctacaggtc
     2161 aagaaacatc aatggaaaaa atagaactgt ttcgtaaaaa tttaggagac ttcccattgg
     2221 ttatagctgc tggagttaca ttagaaaatg caaaaaaaca gcttaaatta ggagatatgg
     2281 caataatagg aagttacttt aaagataatt acaaagattt tggggatgtt agtgtagaac
     2341 acgtaaaaac attcatggat gaaatcaaaa aaattaggga ggaattataa tgattaaatt
     2401 agtaagagta gaccacagac ttatacatgg acaagtagca tttacatgga caaagttttt
     2461 aagcacagac tgtatattga tagcaagtga tgacttatta aaagatgaat tgagaatggc
     2521 aggacttaaa atggctaaac catctaatgt taagttagta atgaaaagca tagcagattc
     2581 tataaaagca cttaactcag gtgttactga taaatacaac ttattgatac tttgtgaatc
     2641 tgtagaagat gtttatagac ttgctaaaga ggtaaaagct attaaatcta taaaccttgg
     2701 tggaacaaaa tcagatgata atcgtgaaaa tatatctaaa gcagtgcatg tatcaaaaga
     2761 tgatataaag atgattaaag agttagattc agaaggcgta aatgtatttg tacaattagt
     2821 tcctgatgat gatgctacaa atgtaatgaa attaatataa ttttaggggg atgaaaatgg
     2881 aatttacaca agttattttg ataactctaa ttgcattctt tgcatatatg catagttttg
     2941 taggttctac aatgcataat agacctatag ttgttgcacc acttgttggt ttagcactag
     3001 gtaatcttca tacaggtata gtaataggtt caacattaga attagtattt atgggtgcat
     3061 ttcctgttgg ggcaagtaat cctcctgatt ttgtgtctgg ttctattatt gccacagcgt
     3121 ttgtaatatt aacgggtcaa gatgtatcag cagcagttgt acttgcagtt cctatagcaa
     3181 ctctagtatt gcttatagat aacttcttaa tgacagtagt acttacatgg ggagctcata
     3241 ttgctgaccg ttatgcagaa gaggggaata ttgaaggcgt agaacgtgtg caattattat
     3301 ttggtatagg aaataaatta atattagcaa taatagtagg tataggattt tcattaggtg
     3361 ttccagtaat agaaaaaata ctttcattta taccatcata tgtaactcat ggaatggatg
     3421 ttgcagcagg cgtgattcct gcaataggtt ttgccatgtt agctagaatg atgcttaata
     3481 agaaaacagt agcattttta ttattaggat ttatattggt tgcttaccta aacataacag
     3541 taacaggagt tgcattgttt ggattagcaa tagctttaat atatgttaac tttgtaggag
     3601 agaaggaggt aatagtagat gacaacgagt tctaagaaat tagagacaat ttcaccagat
     3661 agtaaaataa cgaggaaaga cttttggaaa tgttttagaa ggtcattgac attagattca
     3721 tcttggaact acgaacgtat gcaaaatata gcatatgcat acatgatggc accaataatc
     3781 cgtagattat ataaagatga taaagaaaag aaatctaagg ctttaaaaag acatttagaa
     3841 tttatgtcag ttactcctca tataagtact cttttggtag gtatatctgg agctatggaa
     3901 gaagaaaatg caaagaataa agaatttgat gctaatagta taaatgctgt taaatcaagt
     3961 ttaatgggtc cagtttctgg gataggagat tcatttttct ggggaacatt aaagcttata
     4021 gcagctgggg ttggtatagc tttagcttct cagggtaaca taatgggacc gattttattc
     4081 cttttaataa taaatgttcc tcattttatt atacgctata tatgtctaga taaaggattt
     4141 aagtatggaa ctcaattctt taaagatgtg agtggttcaa gtatagtttc aaaagttatg
     4201 gaagcagctt caatgttagg gcttatggta attggtggta tgactgcatc taatgtaatg
     4261 ttaaaactta gtgttaatgt aggtagtgga gaatgggcag agcctattca aacttactta
     4321 gaccaaataa tgccatgtat gcttccagct atgatattcg gtattatgta ttggttatta
     4381 ggaaaaaagg taaagacaac tacgatatta atttcagtta tgattatttg tatagtattg
     4441 gctgctattg gagtagtata aataaaaaaa tcccaagttc atttgaacga gggatttttt
     4501 gactaaatta aataaaaaag aaagaaggtt cataataatt tataagcatt tatgtgatag
     4561 ttataattag cttattaatt agttataaac tcaaaattaa gcactacttt attaaagtta
     4621 ttatattata atttcgaaat actcacataa tctgtttaga aatttatctt ctaatgggga
     4681 aaaagttttc tttttagagt aaatgaagaa aaactttcta gtaaaatcaa catcctttat
     4741 tttataacat tttattttac ctgcattgag ataatcgata gctgaaatgt acgatataaa
     4801 ggacactcca agacctaatc taaccatttc cttaatagcc tcatttgatt ctacatgagc
     4861 gattacattt aatttactta ctggaaagtt atttttacta agtgtgttta gtattaagtt
     4921 tcttgtacct gacccttctt ttctcataat aaaatttaga taagccaatt ctcctatatc
     4981 gatacaatta tttttattat caattttaaa atctgaagga gtgataagaa caagttcatc
     5041 atctaataag tctaggtact ctatttgagg attattgatt ttagaaccaa ctaatccaaa
     5101 gcttattcgt tcatttaaaa tttctgatat agcatattga gaatcataat ggcttatgga
     5161 aaattttaca tctggataac tcatagaaaa actcttcata aaatcaggta aaatataagt
     5221 ttcaggtatg gaactacatg ctatatctat gataccttct atttttcctg aatattcttt
     5281 tatatcataa attgcacgtt tgcaattatt caatatatat atagcatgtt cataaagaat
     5341 ttcaccagat tttgtgagtg taataacttt gttgcttcta tttataagaa cagtttctag
     5401 ctctctctct aaattctgta tgtgtgcgct tacagtaggt tgagttaaaa aaagttctct
     5461 tgcagccttt gaaaaactct gatgttttgc aacagcaaca aatacttcaa gttgtttaaa
     5521 atccattatt taatcctcct taaattatct aaaactatta taacatattt gataaattaa
     5581 tagtcaaagg tgatttttaa aatagaaaac ctttaaatat tcatggagtt tttgattgtt
     5641 taggaataat ttggtataat gttgtaaggt acttacaata aaaatatcgt aaattgaatt
     5701 ttcaaaattc aactttaaag tgttttttat tacagaaaaa ttacaattag cttcttaatc
     5761 ttattaaatt caaataaata ttatataatt attttataat ataataaata taattattga
     5821 aaaaagagat aactgtaaat tgagatatag ataaatacta taaaatttaa gaaaggagga
     5881 ttgatttatg aagttaaaaa ggtcattagt ttgtgtaact attttaggta ttatacttgt
     5941 tggatgtcat aaagaaaata ctaaagagaa aaatcaagta gcaagtaaag caacacagca
     6001 aaaaactatg acaaaagttc aaaatgatgt taatgaaatt atgaataaag attataagta
     6061 cattataaag aatatgggta taccttataa tacattttat tatataaaac ctaaagtttt
     6121 aaaagaatca aatacaatgc aagatataaa tacatcaagt tatatgacat tagtttatcc
     6181 aaaatatact ggaaatgatg aactagatgg aagtgcttta tatgttgata ttaacgaaaa
     6241 taaagttgtc aatgttgaaa ccaattcttt ctcatcacaa ggtatatcag tcattgatgc
     6301 tgaatctagt atagtgattg aaaaaagtga ccatgaaaaa tcggctgtat cactagaaaa
     6361 ttttagacat attgacctgg gagagtatgt tggtgttgaa gattccagaa taaatgaaat
     6421 tgtaggagat gcgaattatg atttaacagc atataatcat gaaggtagta aagtagttaa
     6481 gagttataga ttgaaagaag ataacaaaat attaaaaaaa gaggtactta caataagtat
     6541 tgtggataac aaaataaaat ctataaaaac tattgaaagt gataaaattg taaaaataat
     6601 aaaaggaact ttattagaat aaaatattct aaagcatatg atgctgtttc aagatagaag
     6661 gaaatttcta gctgggaaca gtttttttat tagatttata aaatttgaac tgcacttata
     6721 gataactatt agttataatt aaatataaga taaaagtatt tccaactttt ataatctata
     6781 atatattaca tagaaatatc ttaaataaaa aatatattgg ggagtattta aaatgataga
     6841 attagaagat gccataaaaa ttattgaaaa aaatgtttta ccaataaaca gggtcaagat
     6901 agtaaatctt atagatgcag taaataaggt agttgcagaa gatatatatt caacaattga
     6961 tagtcctcca tttgataggt caccctatga tggttatgca tataatgcaa attctgaaaa
     7021 tagaaattta aaggttatag ggactttgta tgcaggagat gtatttaata gggtattaaa
     7081 taaaaatgaa gcagtgaaga taatgactgg tggaaagata ccacagggtg caaattgtgt
     7141 aataaaaaaa gaagatgtaa cagttatagg tgatatgata actttaaata taaaattaaa
     7201 ggaatacgat aattacatat ttaagggtga ggatataaaa aaggggcaat tgattattaa
     7261 taaaaatcag aatataggat atgatggtat tggagtatta gcaagtcttg gaatatccaa
     7321 agtaactgtt tatgatgatt taaaagttgg aattttgaat acaggtacag aactacaaga
     7381 tataaatgag actttagaga atggtaaaat atacgatagt aatagatata ccttatattc
     7441 aagattatta aaacttggaa tacaagcaga tacaatatgc aattgttctg atgatatatt
     7501 ggagttagaa aaaaaggtaa agaatatgtt acagagtgta gattttttaa ttaccacagg
     7561 tggtgtttct gttggagata aagatttaat tccagatgta ttcaaaaaaa taggggcaac
     7621 agaattattt tggaagataa acattaaacc tggtggagct tgttatgtag gtacattggg
     7681 agaaaagcta ttatttggtc tttctggtaa tccacatgca gcaatagtgg tatttgataa
     7741 tgtgatagtt cctgttattg agtatttaac atataagaag ggaacacatc atataaaagc
     7801 tatatttaaa ggagaattta ataaactttc aaataaagat agatttgtaa gtggaaaact
     7861 atatacaagt gaaggtaaat tgtatgtaga gctaaatgat aagaaagatg caaaagctag
     7921 actatctgca actctaagaa gtaattgtat gattaagatt aaaaagaatg agacaataaa
     7981 agaaaatcaa ttagtggatg ttgttattag atagttttat gaaaggacac aattttatgt
     8041 ataatatatt gtcagttgtc tcatattcag gagtaggtaa aactacgttg attgaaggca
     8101 taataaaaga attaaataaa aaagggtatc gtgttggagt tattaaacat acctgtcatg
     8161 attttgatat ggatgaggaa ggaaaagata cttataaaca tagaaaatct ggggcgagaa
     8221 aagtctgtat aatatcagat aaacgagtag catatattga agaactaaaa gagaagaatc
     8281 cattatataa aatgattcaa ttatatgaag atatggactt gattatcata gaaggatata
     8341 aaaattatag atttaaaaga ttggaagtaa ctagaaaagg taagtatgag gatattttat
     8401 ctaataagtc tgatttgata ggtattgtca gtgatataga atataaattg aatattgaac
     8461 agtttaattt aaatgattat aaaaatatat caaagtacat agagtcttgt ata
//
LOCUS       DAFAZV010000087         8130 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFAZV010000087 DAFAZV010000000
VERSION     DAFAZV010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8130
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.090"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..327
                     /locus_tag="KOU88_003764"
     CDS             <1..327
                     /locus_tag="KOU88_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213581.1"
                     /translation="LELKAGLMETEFRLGFAKLVRMICRHLGYSPKRVLQTWARNMIQ
                     NDLELAEICSKSVGIISEKTNLKNHPLVDNAEEEEKQIKKEKEDSNQEYNNVIPNNQD
                     GVIDET"
     gene            317..1852
                     /locus_tag="KOU88_003765"
     CDS             317..1852
                     /locus_tag="KOU88_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBK3213582.1"
                     /translation="MKHKDYWKKRFEQLEEAQNNKSIKYYLELEKQYKLAMNSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNKRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNELDSVDKLMRDIYTSGYNYTTFNIQQGIGVGWS
                     LMALDANRVNKIISKPWTSDGLNFSERIWGKHRPALINELHTKLTQSIIRGENPKNLV
                     NDFSKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLKTSNICRE
                     LDGKVFDMKDYQVGVTAPPFHCHCRTTTAPWFEDEEGYRAAKGEDGKTYYVPSNMKYN
                     EWYEKHIEGRLGKEKADTLRKMQLNESKDRKQFEEYKKVLGNEIPSKFDEYQHMKYND
                     TIRYEEAKKLYKDVNWQVKNQRKLTSGSVHSVPFESKPNSVFDNYKDGKLIQRRYYGN
                     TGKPRLDLDLTDHRNPKQHKIVPHKHDWLADENNHDKVKREKDMELTKAHKIANKDIL
                     KGE"
     gene            1854..2102
                     /locus_tag="KOU88_003766"
     CDS             1854..2102
                     /locus_tag="KOU88_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213583.1"
                     /translation="MDNKFKNLQHLIDSIDLGLDIEFDLYNKPYNISIGDDDTRFITL
                     CPNGDTKYYKNGKDMVDNYNIDGKLLKDLWKDIQIVNM"
     gene            2426..2686
                     /locus_tag="KOU88_003767"
                     /pseudo
     CDS             2426..2686
                     /locus_tag="KOU88_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012100325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2933..3205
                     /locus_tag="KOU88_003768"
     CDS             2933..3205
                     /locus_tag="KOU88_003768"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213584.1"
                     /translation="MFKKKYIKKPSKISVRNIIAFIITVIGIALGVFIGINIIMAHVL
                     GIANMVDNNTFTCVRLVYNLVGVISGYLIGKAIYLIASLISYIIYE"
     gene            3256..3486
                     /locus_tag="KOU88_003769"
     CDS             3256..3486
                     /locus_tag="KOU88_003769"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213585.1"
                     /translation="MKEYVIWFKSGNCVSGITDEYVADKLMKDFIEADSDCRNLKGYL
                     DEDGTTIIDLSQIEAISINNCSENNNIGFSKS"
     gene            3533..4105
                     /locus_tag="KOU88_003770"
     CDS             3533..4105
                     /locus_tag="KOU88_003770"
                     /inference="COORDINATES: protein motif:HMM:NF018515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HBK3213586.1"
                     /translation="MKKGELIALGLSEEDAKKVEAESLKELENYINKIEYEKVKEELK
                     ASKEAIEGFKDGMTKEQIEELKKGYETKLTAKDEEYQKKLKEKEQKEFDMALENELIK
                     LNVHSTKAAKAELDLEKIKYENGAFTGLKEQTDTWSTQKSFLIKTGETKINYNPDNGK
                     KNTLSRAENIAKEKNEEGSKNPYADAWSIK"
     gene            4121..4501
                     /locus_tag="KOU88_003771"
     CDS             4121..4501
                     /locus_tag="KOU88_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213587.1"
                     /translation="MYFKEVNFDNTPEFLASQHYINFSKTALDTDVVADENGKKYVLA
                     GSLLGESGKVVKITRGGSSGSYTYTLSEDPVGIVFSTVDVTYGPQPVASMVEGYVITE
                     RLQGEYVKEAIDTIKTKLPNIKFM"
     gene            4513..5532
                     /locus_tag="KOU88_003772"
     CDS             4513..5532
                     /locus_tag="KOU88_003772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002591054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HBK3213588.1"
                     /translation="MARVEELLSVQELINYTKTRKLKETMGDLLFPTQKIEGLEIKMI
                     KGASNLPVSASVHAFDTEAEIASREGANLSIAELALVKRKIKLDEKDIIVLEEPRNSQ
                     EETQMINQIFNDVDNLVSSVNTRIEAMRMEVLTTGELNINENGVKASLKYGTPTNHKE
                     TKTWSSGTPDILGDIYNMTDKIVVDTGFTPTRSLTSKTILNTILRDEKLRKAIFGVNS
                     DKLLTLKELNVFLASQSLPPIFTYDERYRVQGKDGKYTTKRFLDENKFILMPDGKMGD
                     TFFGLTAEELELRKNPSIDISSVGNIIVEQYSTADPVAKWIKAVATVLPSFPYADQVF
                     MGTIN"
     gene            5543..5887
                     /locus_tag="KOU88_003773"
     CDS             5543..5887
                     /locus_tag="KOU88_003773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HBK3213589.1"
                     /translation="MEVERLKKLLGFSREDDSKDTILEFILEDVEEMVKNYCNVPTIP
                     EQLNSTILRMAIDMYKNESLGSEDIALGSISSISEGDTSVSYRSSASEFKESLLKDYK
                     SQLNRYRKLRWK"
     gene            5887..6249
                     /locus_tag="KOU88_003774"
     CDS             5887..6249
                     /locus_tag="KOU88_003774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213590.1"
                     /translation="MMDKTRKAIEMLYRDKCTIVEYQPIKDPVTKRANNKEVVVLENQ
                     PCKLSYKNITSATDGKVAKLVQTIKLFISPNINIKAGSKLIITTQNNITKEYIRSGES
                     AIYPNHQEIILELFKDKA"
     gene            6249..6674
                     /locus_tag="KOU88_003775"
     CDS             6249..6674
                     /locus_tag="KOU88_003775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK3213591.1"
                     /translation="MARWGSVDFREFKRVCKKMEKLTKIDLDKFCKDAARELAARLLG
                     KVIRRTPVDTGFLRQGWNGVAYARSLPVYKQGNNYIIEVVNPTEYASYVNFGHRTKDG
                     KGWVKGQHFLTISEMELQSQVDKIIEKKLLILLKGVFDA"
     gene            6667..7104
                     /locus_tag="KOU88_003776"
     CDS             6667..7104
                     /locus_tag="KOU88_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213592.1"
                     /translation="MLNNIIDGISVKLDKSFGEKYTIYSEDVEQGINEPCFFIVPLNP
                     SKTPYPSGRELKKNSFDVHYFPRSEAKNFEINEIAEMLLEELEYIEIDGDLVRGTNMN
                     FEIIDNVLHFFVDYNYFTIKNNDTNKMDTVELFGGLKRGDNFE"
     gene            7097..7273
                     /locus_tag="KOU88_003777"
     CDS             7097..7273
                     /locus_tag="KOU88_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213593.1"
                     /translation="MNKTLSKEDDYKFTKEQIVNSKKYVNRKDLLNAILKENELYSFS
                     EVEEIINKFMKGVS"
     gene            7274..>8130
                     /locus_tag="KOU88_003778"
     CDS             7274..>8130
                     /locus_tag="KOU88_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBK3213594.1"
                     /translation="MALGGGTFVTQNKILPGSYINFVSATRATSSLSDRGIVAMPLEL
                     DWGIDEEVFQVTSDDFEKYSTKYFGYDYTHEKLKGLRDLFKNIRLGYFYKLNKGVKAS
                     CSIATARCSGIRGNDLKVIVTTNIDDNAKFDVVTLLDNKKVDTQIAKVITELQDNDYV
                     TWKKEATLEATAGLTFTNGTNGEAVTGTEYQAFLDKIESYSFNALGCLATTAEIKSLF
                     VEFTKRMRDKVGAKFQTVLYKKNDADYEGIVSVENKIKDKDLAESSLIYWTTGAIAGC
                     DINKSNTNKR"
BASE COUNT         3361 a          818 c         1562 g         2389 t
ORIGIN      
        1 ttagaattaa aagcaggact tatggaaaca gagtttagat tagggtttgc taaactagta
       61 agaatgatat gtagacattt aggatattct cctaaaaggg ttttgcaaac ttgggctagg
      121 aatatgattc aaaatgattt agaactagct gagatatgct ctaagagtgt tggaataata
      181 tcagaaaaga ctaatttaaa aaatcatccg cttgtagata atgcagagga agaagaaaaa
      241 cagattaaaa aagaaaagga agatagcaat caagaataca ataatgtaat tcctaacaat
      301 caagatggtg ttatagatga aacataaaga ttattggaag aagagatttg aacaattaga
      361 agaagcacaa aataataaga gcataaaata ttatcttgaa ttagaaaaac aatataaact
      421 agctatgaat agtatagaaa aagatatatt agcatggtac aacagatttg ctaaaaacga
      481 aggaatatct ttattagaag ctaagaaact attaaataaa agggagctag aagagtttaa
      541 gtggagtgta gaagaatata ttaaatatgg taaagaaaat gctataaatc aaaagtggat
      601 gaaagagtta gaaaatgcta gtgcaagagt tcatataaca aggcttgaag ctttaaaact
      661 gcaaatacaa caacaagtag aagttctcta tggaaatgaa ttagatagtg ttgataagct
      721 aatgagggat atttatacaa gtggatataa ttatacaact tttaatattc aacaaggtat
      781 tggtgttggc tggagcttaa tggctttaga tgcgaataga gtaaataaga ttatctcaaa
      841 accttggact agtgatgggt taaattttag cgaaagaatt tggggtaagc atagacctgc
      901 tttaatcaat gagttacata ctaagctaac tcaatcaatt attagaggtg aaaatccaaa
      961 gaacctagta aatgactttt ctaagagatt taatgtatct aaatcacaag ctaagaattt
     1021 gataatgact gaatcagctt tctttgcatc agcttcaaga aaagattgtt tcaatgattt
     1081 agatgtagag aagtatgaga ttattgccac actagactta aaaacatcaa atatatgtag
     1141 agagttagat ggaaaagtat ttgatatgaa ggattatcaa gttggagtta cagctccacc
     1201 atttcattgt cattgtagga caacaacagc tccttggttt gaagatgaag aaggttacag
     1261 agcagcaaaa ggagaagatg gaaaaacata ttatgtacca tctaatatga agtataatga
     1321 gtggtatgag aaacatatag agggtagact tggaaaagaa aaagctgata ctcttagaaa
     1381 aatgcaacta aatgagagta aagatagaaa acaatttgaa gaatataaaa aggtattagg
     1441 aaatgaaata ccttctaaat ttgatgaata tcaacatatg aagtataatg atactataag
     1501 gtatgaggaa gctaaaaagc tttataagga tgtaaattgg caagttaaga atcagagaaa
     1561 attaactagt ggaagtgttc attcagtgcc atttgaatca aaaccaaata gtgtatttga
     1621 taattacaaa gatggtaaat taattcaaag aagatactat ggtaatacag gaaaacctag
     1681 attagattta gacttaactg accatagaaa cccaaagcaa cataaaattg tacctcataa
     1741 acatgattgg ttagctgatg aaaataacca tgataaggta aaaagagaga aggatatgga
     1801 gcttacaaaa gctcataaaa tagcaaacaa agatattttg aaaggagagt aaaatggata
     1861 ataaatttaa gaatttacaa catttaattg attctattga tttaggatta gatatagaat
     1921 ttgacttata taataaacca tataatatat ctattggaga tgatgataca aggtttatta
     1981 ctctttgccc taatggagat acaaagtatt ataaaaatgg taaggatatg gttgataatt
     2041 acaacattga tggtaaatta ctaaaggatt tatggaaaga tatacaaata gtaaatatgt
     2101 aaaagcactt gctaagttat aaattagtag gtgcttttat tatgtaaaaa tttattgaga
     2161 gggtgatttg aaatgcttaa attatatatt ttatcaataa ttgtgttttg tacagggctt
     2221 tatttattca acatgaaggt ttatagtaat gaggaattaa ttgaattact taaaagtgtg
     2281 aatatcagaa aaagaaaaaa atataatttt atttttctag ctttatttcc actacttaat
     2341 tttattcttg gtgtgatact catactatat tctttgctag ttagcaatga agatattatt
     2401 aaatatttaa ggaggaataa ataagatggc taagtttaaa aagaaagcag ttgaagtaga
     2461 agcttttaaa ctaggttatg atgtagaacc aaaatggttt attgagaatg atagagtttg
     2521 taattttatg caagaaaaat gtattaatgg tcatataagt tgtgatttaa agacactaga
     2581 aggtactatg agagctaata aaggggatta cattatacaa ggtgtaaaag gagaaatata
     2641 tccatgtaaa gcagatatat ttgaaatgac ttatgagaaa gttgaatata gagaaaaaaa
     2701 taaattatca acagagatga ctttagattc aacaaacttt caagaaaata ttaaaaaagc
     2761 tagaaaagaa ttagatttat ttatacaaac tttagaaaaa gcagatgata aaattaataa
     2821 actagcagaa aaaatgaata aatgtgattg taaagttgat atagataaga ttgtaaaaca
     2881 gttagtggaa cacctaagag aaggtattga ataagttttg ggggatggaa atatgtttaa
     2941 aaagaaatat attaaaaagc caagcaaaat aagtgttaga aatattatag catttattat
     3001 tacagttatt ggtatagctt taggtgtttt tataggtatc aacataatta tggctcatgt
     3061 tttaggtata gctaacatgg tagataataa tactttcaca tgtgttagat tagtttataa
     3121 cttagtaggg gttataagtg ggtatttgat aggaaaagca atatacctta tagcttcact
     3181 aataagctat attatttatg aataatttgt ttaaaggttt tttattaggt aaaaaacaaa
     3241 aggagggttg tattattgaa agagtatgta atttggttta agagtggaaa ttgtgtatct
     3301 ggaataacag acgaatatgt tgctgataag ctaatgaaag attttattga agctgactca
     3361 gattgtagga acttgaaagg atatttagat gaagatggaa caacaataat agatttatca
     3421 caaatagaag ctatatcaat aaataattgt agtgagaata ataatattgg ttttagtaag
     3481 tcctagatag ggctttttta ttatgtaaaa aatgaaagga gaattaaata aaatgaaaaa
     3541 aggtgaatta attgcattag ggcttagtga agaagatgca aaaaaagtag aagctgaatc
     3601 attaaaagaa ttagaaaatt atattaataa aattgagtat gaaaaggtaa aagaagaatt
     3661 aaaagcatca aaagaagcaa ttgaaggttt taaggatgga atgacaaaag agcagattga
     3721 agagcttaaa aaaggctatg agactaaatt aactgcaaaa gatgaagaat atcaaaagaa
     3781 attaaaggaa aaagaacaaa aagagtttga tatggcatta gaaaatgaac ttattaaact
     3841 taatgttcat agcactaaag cagcaaaagc agaacttgat ttagaaaaaa taaaatatga
     3901 gaatggtgct tttacaggac taaaggaaca gactgatact tggtcaactc aaaaatcttt
     3961 tttaataaaa acaggagaaa ctaagataaa ttacaaccct gataatggca aaaaaaatac
     4021 attaagtaga gctgaaaata ttgctaaaga aaagaatgag gaaggttcta aaaatccata
     4081 tgctgacgca tggagtataa aataaaaagg aggataaagt atgtatttta aagaggtaaa
     4141 ttttgataac acacccgagt ttttagcttc tcaacactat attaactttt caaaaacagc
     4201 attagataca gatgtagtgg ctgatgaaaa tggaaagaaa tatgtgttag caggtagttt
     4261 attaggtgag agtggcaaag tagtaaagat aactagagga ggttcttcgg gtagttatac
     4321 atacacatta tcagaagacc ctgtaggaat agttttttca actgtagatg ttacttatgg
     4381 accacaacca gttgcatcaa tggtggaagg gtatgtaata actgaaagat tgcaaggtga
     4441 gtatgtaaaa gaagctatag acactataaa gacgaaatta ccaaatatta aatttatgta
     4501 ggaggatgaa atatggcaag agtagaagaa ttattgtcag ttcaagagct gataaactat
     4561 acaaagacta gaaaattaaa agaaacaatg ggagatttat tatttccaac tcaaaagata
     4621 gaaggacttg aaataaagat gataaaaggt gcatctaatc ttccagtatc agcaagtgtt
     4681 catgcttttg atacagaagc agaaattgca tcaagagaag gtgctaattt aagtattgct
     4741 gaacttgcac ttgtgaaaag aaaaataaaa ctagatgaaa aagatataat tgtacttgaa
     4801 gagccaagaa actcacaaga agaaactcaa atgataaatc aaatatttaa tgatgttgat
     4861 aatcttgtat caagtgtaaa tactagaata gaagcaatga gaatggaagt tctaacaaca
     4921 ggagaactta atataaatga aaatggagtt aaagcttctt taaaatatgg aactccaaca
     4981 aatcataaag aaacaaaaac ttggtctagt ggaacaccag atatattagg agatatttat
     5041 aatatgactg ataaaatagt tgttgatact ggatttactc caacaaggtc attaacctct
     5101 aaaactattt taaacacgat attaagagat gaaaaactaa gaaaagctat atttggtgta
     5161 aatagtgata aattgcttac tttaaaagaa ttaaatgtat ttttagcttc tcaatctctt
     5221 cctcctattt ttacttatga tgaaagatat agagttcaag gtaaggatgg taaatacaca
     5281 acaaagagat ttttagatga aaataagttt attcttatgc ctgacggcaa gatgggagat
     5341 actttctttg gattaacagc agaggaatta gaacttagaa aaaatccatc aatagacatt
     5401 agttcagttg gaaatataat tgtagagcag tattctactg ctgacccagt tgctaagtgg
     5461 ataaaagcag ttgcaacagt cttacctagt tttccttatg ctgaccaagt gtttatgggt
     5521 acaataaatt agaggtgtta atatggaagt tgaaagacta aaaaagcttt taggatttag
     5581 tagagaagat gattcaaaag atacaatact agagtttata ctagaagatg tagaagaaat
     5641 ggtcaaaaac tattgtaatg tacctactat accagaacaa ttaaatagta ctattttaag
     5701 aatggctata gatatgtata aaaatgagag tctaggaagc gaagatattg cactaggctc
     5761 tatttcttct atatcagaag gtgatacatc agtttcctac agaagttcag ctagtgaatt
     5821 taaggaatct ttacttaaag attacaagtc acaattaaat agatacagaa aacttaggtg
     5881 gaaataatga tggataagac tagaaaagca atagaaatgc tgtatagaga taaatgcact
     5941 atagtagagt atcagccaat taaagaccct gtaacaaaac gagctaacaa taaagaagta
     6001 gtcgtattag aaaatcaacc ttgtaagtta tcatataaaa atattacatc agctacagat
     6061 ggaaaagtag ctaaacttgt acagactatt aaactcttta tatctccaaa cataaacatt
     6121 aaagcaggtt caaaacttat tataactact caaaataata ttacaaaaga atatataaga
     6181 agtggagaat cagctatata tccaaatcat caagaaataa tacttgagtt atttaaggat
     6241 aaagcataat ggctagatgg ggcagtgttg attttagaga gtttaaaaga gtttgtaaaa
     6301 agatggagaa gcttacaaag attgatttag ataagttttg caaagatgca gcaagagaat
     6361 tagcagcaag actcttagga aaagtaatta gaaggacacc agttgataca ggattcttaa
     6421 gacaaggatg gaatggagtg gcttatgcta ggtcgcttcc tgtgtataaa caaggaaata
     6481 attatattat agaggttgtt aatccgactg aatatgcaag ttatgtaaat ttcgggcata
     6541 gaactaaaga tggaaaaggt tgggttaaag gacaacattt cttaacaatt tcagagatgg
     6601 aactacaaag ccaagttgat aagattatag agaaaaagtt attaatatta cttaaaggag
     6661 tatttgatgc ttaataatat tatagatgga atatcagtaa agttagataa atcatttgga
     6721 gaaaaatata caatttatag tgaggatgta gagcaaggta ttaatgaacc ttgttttttt
     6781 attgttcctt taaatccaag caagacacca tatccaagcg ggagagaatt aaagaaaaat
     6841 tcttttgatg tacattattt ccctcgttca gaagctaaga attttgaaat aaatgagata
     6901 gctgagatgc tactggagga attagagtat atagaaattg atggagattt agtcagaggt
     6961 acaaatatga attttgaaat tatagacaat gttcttcact tctttgttga ttataactat
     7021 tttactataa aaaataatga taccaataag atggatacag tagagttatt cggtggtttg
     7081 aagagaggtg ataattttga ataaaacatt aagcaaagaa gatgactaca agtttactaa
     7141 ggagcaaata gttaattcta agaagtatgt aaatagaaaa gacttattaa atgcaatttt
     7201 aaaagaaaat gagttatatt ccttctcaga ggtagaggaa ataataaata aatttatgaa
     7261 aggagtgagc tagatggcgt taggtggagg aacatttgta acacagaata aaatattacc
     7321 aggtagctat ataaactttg taagtgccac aagggcaacc agttcactta gcgatagagg
     7381 tattgttgca atgcctttag aacttgattg gggaattgat gaagaagtat ttcaagtgac
     7441 tagtgatgat tttgagaagt attcaactaa gtattttgga tatgattata cacatgagaa
     7501 gttgaaaggt ttgagagatt tatttaaaaa tataaggcta ggatatttct ataaattaaa
     7561 taaaggtgtt aaagctagtt gtagtattgc tacagctaga tgcagtggta taagaggtaa
     7621 tgacttaaaa gttatagtaa caacaaatat agatgataat gctaaatttg atgttgtaac
     7681 acttttagat aataagaaag ttgatactca aatagctaaa gttattacag aactgcaaga
     7741 taatgattat gtcacttgga agaaggaagc aacattagag gctacagcag gattaacttt
     7801 tactaatgga actaatggtg aagctgtgac aggaacagag tatcaagctt ttcttgataa
     7861 gatagaaagt tactcattta atgcactagg atgtttggct acaacagcag agattaaaag
     7921 tttgtttgta gagtttacta agagaatgag agacaaagtt ggggctaagt ttcaaactgt
     7981 attatataaa aagaatgatg cagattatga aggcatagta tctgtagaaa ataagattaa
     8041 ggataaagat ttagcagagt ctagtctaat ttactggact actggagcta tagctggatg
     8101 tgatataaat aaatctaaca ctaacaagcg
//
LOCUS       DAFAZV010000088         8025 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFAZV010000088 DAFAZV010000000
VERSION     DAFAZV010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 8025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8025
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.091"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(208..1785)
                     /locus_tag="KOU88_003779"
     CDS             complement(208..1785)
                     /locus_tag="KOU88_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp5"
                     /protein_id="HBK3213595.1"
                     /translation="MKAPKTILTILTIALTLSSISIIPSYALTEEKLIGNGRYETAVK
                     ISQKAYSSSSNVVLVNDNSLADALSATPFAKAKGAPILLTESDKLDDRTEKEIKRLGA
                     KDIYLIGGTAVLNKDIENKLKGNGLNVERINGKDRYETSLILANKLKDIKDIKEVAVV
                     NGEKGLSDAVSVGAPAAQNKMPIILSSPKDGVEAFDKFIRDEKVIKAYVIGGTNSVSR
                     AVEKSLPNAERVSGKDRNETNAKVIEKFYTDTNLSNLYVTKDGSKNENQLIDSLAVGV
                     LAAKNESPVVLVGNKLNTKQRDILSTKKLNTITQVGGNGNEEAFDEIISLQEKTVFEA
                     KTVEELTDMINIASPNDIINFKPKEDTVNEAFRMVTNKPITVNIKGDCSKTITVDMPN
                     GEVNNYATLVNVIVRNIGEGGFNNHDTITILSVRDKNGRVIENTRNSDIDTLMILASA
                     NDTKLINDGYIGKLIDNSSNSDITNNGNIDKKVNQVEDLEAKVDSIEKAIDSISQKVN
                     KIQDILDKLGFLKKFLS"
     gene            complement(2082..4493)
                     /locus_tag="KOU88_003780"
     CDS             complement(2082..4493)
                     /locus_tag="KOU88_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding cysteine protease Cwp84"
                     /protein_id="HBK3213596.1"
                     /translation="MRKYKSKKLSKLLALLTVYFLIVSTIPVSAENHKTLDGVETAEY
                     SESYLQYLEDVKNGDTAKYNGVIPFPHEMEGTTLRNKGRSSLPSAYKSSVAYNPMNLG
                     LTTPAKNQGSLNTCWSFSGMSTLEAYLKLKGYGTYDLSEEHLRWWATGGKYGWNLDDM
                     SGSSNVTAIGYLTAWAGPKLEKDIPYNLKSEAQGATKPSNMDTAPTQFNVTDVVRLNK
                     DKETVKNAIMQYGSVTSGYAHYSTYFNKDETAYNCTNKRAPLNHAVAIVGWDDNYSKD
                     NFASDVKPESNGAWLVKSSWGEFNSMKGFFWISYEDKTLLTDTDNYAMKSVSKPDSDK
                     KMYQLEYAGLSKIMSNKVTAANVFDFSRDSEKLDSVMFETDSVGAKYEVYYAPVVNGV
                     PQNNSMTKLASGTVSYSGYINVPTNSYSLPKGKGAIVVVIDNTANPNREKSTLAYETN
                     IDGYYLYEAKANLGESYILQNNKFEDINTYSEFSPCNFVIKAITKTSSGQATSGEALT
                     GADRYETAVKVSQKGWTSSQNAVLVNGDAIVDALTATPFTAAIDSPILLTGKDNLDSK
                     TKAELQRLGTKKVYLIGGENSLSKNVQTQLSNMGISVERISGNDRYKTSISLAQKLNS
                     IKSVSQVAVANGVNGLADAISVGAAAADNNMPIILTNEKSELQGADEFLNSSKITKSY
                     IIGGTATLSSNLESKLSNPTRLAGSNRNETNAKIIDKFYPSSDLKYAFVVKDGSKSQG
                     DLIDGLAVGALGAKTDSPVVLVGNKLDESQKNVLKSKKIETPIRVGGNGNESAFNELN
                     TLLGK"
     gene            4721..5119
                     /locus_tag="KOU88_003781"
     CDS             4721..5119
                     /locus_tag="KOU88_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBK3213597.1"
                     /translation="MIFKKHKETILYLFFGTLTTFVNIISYLFFTRVVSLNFIIANIL
                     AWILAVLFAYFTNKFFVFESKVIEIAFLFKEFLSFVSFRLFSGITEMLIMYIMIDLLF
                     INDIIVKVFTNIIVIVLNYVFSKMIIFKKL"
     gene            complement(5180..5887)
                     /locus_tag="KOU88_003782"
     CDS             complement(5180..5887)
                     /locus_tag="KOU88_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBK3213598.1"
                     /translation="MIEATLFFSPHQDDEILSMGSAIIEHVEKSDTHVILCTDGSKSV
                     IRKVLDDGGACSYHIKDIHKYSLSEDEFSYNRDDEFKNSCKEMGVKESNIHIEENRAH
                     DGELNKEKAKEIILKYLEEYPNAKVKTVTPYKASGIHEDHRALGEAALELYKEGKIKD
                     LRFYVEPYDYNDFKKVNPNVKVWKLANSQENKLLNAMNAYKKWNPESGKYAIGYHSVK
                     SHFDELKSNKIQYVHAP"
     gene            complement(5958..6395)
                     /locus_tag="KOU88_003783"
     CDS             complement(5958..6395)
                     /locus_tag="KOU88_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small multi-drug export protein"
                     /protein_id="HBK3213599.1"
                     /translation="MEYVNLIFLSMIPIVELRGAIPMGLALNLNPVLVYISCIIGSTV
                     IGIPILLTFRYMLDYLKVKGYFKCFVDFVENKLHNRAKKLKSLSIVGIVLFVGVPLPT
                     TGTWSAACIASLLRMRLKDAILGIFLGNIVSGCVVFAISYHIF"
     gene            complement(6468..7862)
                     /locus_tag="KOU88_003784"
     CDS             complement(6468..7862)
                     /locus_tag="KOU88_003784"
                     /EC_number="2.7.8.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011461019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate glucose
                     phosphotransferase"
                     /protein_id="HBK3213600.1"
                     /translation="MIKENQKLLNNIQMIIDLIIILSSFILAYYTKFNLLAGVNSIGV
                     YGYIITAICSVVMYFILYNILDLYSAKRTSNLYKEIKEIINANIIGALILTLILFIIK
                     LINYSRIVLMLFVMYNVILTSLSRVVLRSILRKYRSKGFNQKHCLVVGATETGKKLIG
                     KIKKNKQWGYNIIGCLDDDLYHLDRFEEILILGTIDEIETILEKTHVDIVFITIDSEK
                     FYKFGEIIKQCEKAGVKTNIVPYYYNYVPSKPYMDDLDGFPIIDTRHVPLDNYFNNAC
                     KRLFDIIFSIIGIIITLPIMLFSILMIKLTSSGKIIYKQTRVGLNRKNFDMYKFRSMK
                     TQKEEEEITKWTTKNDSRKTKWGSIMRKTSIDELPQFFNVIKGDMSIVGPRPERPYFV
                     DKFKYEIPRYMIKHQVRPGITGWAQVNGYRGDTSIEKRIEYDLYYIENWTFLFDVKIV
                     FFTIFKGILNKNAY"
BASE COUNT         2493 a         1355 c          873 g         3304 t
ORIGIN      
        1 agattatttt tctttattct agttttgtca atacttttat ttattttttt gttacattca
       61 attccaatcc ccatattacc tccccaaagc ttattcaaat atatattgaa ctacatattt
      121 atctataagt ctgtttgtat ataaacctgt ttaactatat aactttagaa caattacaac
      181 acacacttca cttaaatata catattctta gctaagaaat ttctttagaa atccaagctt
      241 atctagtata tcttgtattt tattgacttt ctgacttata gaatctatag ctttttcaat
      301 tgaatcaacc ttagcctcta aatcctcaac ctgattaact tttttatcta tattaccatt
      361 attagttata tcactattag atgaattatc tataagtttt cctatatatc catcattaat
      421 caattttgta tcattagcag aagctaatat catcaacgta tctatatctg aatttctagt
      481 attttctata actctaccat ttttgtcacg aactgacaat atagtgattg tatcatgatt
      541 attaaatcca ccttctccaa tatttctaac tataacattt accaaagtag catagttatt
      601 cacttcacca ttaggcatat ctactgtaat agtctttgaa caatctccct ttatattcac
      661 agttattggt ttatttgtta ccattctaaa agcttcattt acagtatcct cttttggttt
      721 aaagtttata atgtcattag gacttgctat atttatcata tcagttaatt cctcaacagt
      781 ttttgcttca aacacagttt tttcttgtag acttataatt tcatcaaaag cttcttcatt
      841 tccatttcca cctacctgtg ttatagtatt taatttttta gtactaagta tatctctttg
      901 ttttgtgttt aatttattac caaccaaaac aacaggagac tcattttttg cagccaatac
      961 tccaacagct aacgagtcta ttagctgatt ctcattttta ctaccatcct tagttacata
     1021 taaattactt aagtttgtat cagtgtaaaa cttttctata actttagcat tagtctcatt
     1081 tctatctttt ccactcactc tttctgcatt aggaaggctc ttttctacag ctcttgaaac
     1141 agaatttgta cctccaatta catatgcttt tataactttc tcatctctta taaatttatc
     1201 aaatgcttct actccatcct taggactaga caaaattata ggcatcttat tttgagctgc
     1261 tggtgctcca acactaacag catcactcaa tcctttttca ccatttacta cagcaacttc
     1321 cttaatatct tttatatcct taagcttatt agccaaaatc agtgaagttt catatctatc
     1381 cttaccatta attctttcta cattaagtcc attacctttt aacttgttct ctatatcttt
     1441 attaagtaca gcagtacctc ctatcaaata aatatcttta gctcctagac gttttatctc
     1501 tttttcagtc ctatcatcta gcttatcact ttctgtcaaa agtattggtg ctcctttagc
     1561 ctttgcaaat ggtgtagctg aaagtgcatc agctaatgaa ttgtcattaa ctaacactac
     1621 attagaacta gaactgtatg ccttttgact tatctttaca gcagtttcat atctaccatt
     1681 acctattaat ttttcctctg taagtgcata tgatggtatt atagaaatgc tacttaaagt
     1741 aagcgctatt gtcagtattg ttaaaatagt ttttggtgct ttcattatta ttccccctta
     1801 ttttgtttaa aatcttacta tatttatatt ataaaataac tttacactat tttacagttt
     1861 aaaattatta catttttcat caataataag aaaactatct aaaaatatag acaaacttat
     1921 ttttcattat ttaaatgata aaaatataaa ataacaaaaa agagtgcctc atgaactaaa
     1981 aacttcattt tgagacaccc ctttttgtta ttttatattt ataaacttct attgaatatt
     2041 ttttaataat aaaatgtata tccttactat cttttcattc actattttcc taaaagagta
     2101 tttagttcat taaaagcact ttcatttcca tttccaccaa ctctaatagg agtttctatt
     2161 ttcttagact taagtacatt tttttgactt tcatctaact tatttccaac tagaactact
     2221 ggcgaatcag ttttagcacc taatgctcct actgctaatc catctatcaa gtctccttga
     2281 ctctttgaac catctttaac aacaaaagca tatttcaaat ctgaactagg gtagaattta
     2341 tctattatct tagcattagt ttcatttcta ttacttcctg caagtcttgt tggatttgaa
     2401 agcttacttt ctaaatttga tgataaagta gctgttccac caattatata agacttagtt
     2461 atttttgatg aatttaaaaa ctcatcagca ccttgcaact cactcttttc attagtaagt
     2521 attattggca tattgttatc agcagctgct gcaccaacac ttattgcatc tgcaagtcca
     2581 tttacaccat ttgccactgc aacttgtgag acagatttta tactatttaa cttttgagct
     2641 agagatatac tagtcttgta tctatcatta cctgaaattc tttctaccga tatacccata
     2701 ttgctaagtt gagtttgtac attcttactt aaagaatttt ctccacctat tagataaact
     2761 tttttagttc ctaatctttg taactccgcc ttagtttttg aatctaagtt atcttttcct
     2821 gttaaaagaa ttggagagtc gattgctgct gtaaatggtg tagctgttaa agcatccact
     2881 attgcgtctc catttactaa tactgcattt tgtgaagaag tccatccttt ttggctaact
     2941 ttaactgctg tttcatatct atctgctcca gttaaagctt ctcctgaagt agcttgtcca
     3001 gaagatgttt ttgttatagc ttttataaca aagttacaag gagaaaattc actatatgta
     3061 tttatatctt caaacttatt gttttgaagt atgtagcttt cacctaagtt tgctttagcc
     3121 tcatatagat agtatccatc tatattagtt tcatatgcta aggttgattt ttctctatta
     3181 ggatttgctg tgttgtctat aactactact attgctcctt taccttttgg taaactgtaa
     3241 gaattagtag gtacatttat gtatccagaa tatgatactg ttccacttgc aagttttgtc
     3301 attgaattgt tttgaggaac tccatttact actggtgcat aatatacttc atattttgct
     3361 cctacagagt ctgtttcaaa cataacagaa tcaagttttt cagaatctct gctaaaatca
     3421 aatacatttg ctgctgttac tttatttgac attatcttac taagaccagc atattcaagt
     3481 tggtacattt ttttatcact atctggtttt gatactgatt tcattgcgta gttatctgta
     3541 tctgttagta gagtcttatc ttcataagaa atccagaaga atcctttcat agaattaaac
     3601 tctccccaac tgctttttac taaccatgct ccatttgatt ctggttttac atcagatgca
     3661 aagttatctt ttgaataatt atcatcccat cctactatcg ctacagcgtg atttaatgga
     3721 gctctcttat ttgtacagtt atatgctgtt tcatctttat taaaatatgt tgaataatgt
     3781 gcataacctg atgtcactga accatattgc attatagcat tttttacagt ttccttatct
     3841 ttattaagac gaacaacatc tgttacatta aattgagtag gtgcagtatc catatttgaa
     3901 ggtttagttg caccttgtgc ctcagattta agattatatg gtatatcttt ttctaactta
     3961 ggacctgccc atgctgtcag atatcctatg gctgttacat ttgaactacc tgacatatca
     4021 tctaagttcc atccatattt tccaccagtt gcccaccatc ttaaatgttc ttctgataag
     4081 tcatacgttc catatccttt taatttaaga tatgcttcta aagttgacat acctgaaaaa
     4141 gaccagcatg tattaagact tccttgattt tttgctggtg tagtaagacc aagattcatt
     4201 gggttgtatg ctacacttga tttatatgct gatggaagac tacttctacc cttatttcga
     4261 agtgttgtac cttccatttc atgtggaaaa ggtattactc cgttatattt tgctgtgtct
     4321 ccatttttga catcttctag gtattgaaga tagctttcag aatactctgc agtttctact
     4381 ccatctagag ttttatggtt ttctgctgag acaggtattg ttgacactat taaaaagtaa
     4441 actgtcaaca atgctagtag ctttgacaat ttttttgatt tgtactttct catgtttacc
     4501 cccttatatg tatttaattt ttattatatc agatttctaa atctaggtca tattttattt
     4561 tgataaaata aaaattgtaa gtaaatatta attgtaaaat attataattt tattttttat
     4621 gatattttac aatatgtcta tttgttaact gatatgctat actaaagtgt attagtgttt
     4681 ttaaagatag ttatatttga ttagtttagg agggttatat ttgattttta aaaaacataa
     4741 agagaccata ttatatttat tttttggaac acttactact tttgtaaata taatttcata
     4801 tttatttttt actagagttg tatcacttaa ttttataatt gcgaatattt tagcatggat
     4861 tcttgctgtc ttatttgcct attttactaa taagtttttt gtatttgaaa gtaaggtaat
     4921 tgagatagct ttcttattta aagaattctt atcttttgtt agttttagat tattttctgg
     4981 tattactgaa atgttaatta tgtatataat gattgattta cttttcataa atgatattat
     5041 agtaaaagtc tttactaaca taattgttat agttttgaat tatgtattta gtaaaatgat
     5101 aatttttaag aaactataat aaaaaatagt ctgctgaagt agcagactat tttttattat
     5161 atatgaggcg aattgtaagt taaggagcat gtacatattg aatcttattt gactttaact
     5221 catcaaaatg tgattttaca gaatgatatc ctattgcata ttttccactt tctggattcc
     5281 attttttata agcattcata gcatttagta gtttattttc ttgactattt gctaacttcc
     5341 agacctttac atttggatta acttttttaa agtcattata atcatatggc tctacataaa
     5401 atcttaaatc ctttattttt ccttctttat ataactctaa tgctgcctca cctagtgctc
     5461 tatggtcttc atgtattcca cttgctttat atggagtgac tgtttttact tttgcatttg
     5521 gatattcctc aagatatttt aatattatct cttttgcttt ttctttgtta agttctccat
     5581 catgagctct attttcttct atatgtatat tactttcttt gacacccatt tctttacagc
     5641 tgtttttaaa ctcatcatcc ctattatacg aaaattcatc ttctgataaa gaatacttat
     5701 gtatatcttt tatatgatat gaacatgccc ctccatcatc caaaactttc cttatgactg
     5761 atttacttcc atccgtacat aatataacat gcgtatcact tttttcaaca tgttcgatta
     5821 ttgcacttcc catacttaaa atttcatcat cttgatgtgg tgaaaaaaat aaagttgcct
     5881 ctatcaatta cgttcctcct attctataaa taaaaataaa tgtttattta aaagctttac
     5941 tattctacta aatgtactta aaatatatga taagatatag caaaaactac acatcctgaa
     6001 actatatttc caagaaatat acctaaaatt gcatctttca atctcattct aagtaaagaa
     6061 gctatgcatg cagcactcca tgttccagtg gttggtaatg ggactccaac aaataaaaca
     6121 atacctacaa tacttagcga cttcaatttt tttgctctat tatgtagttt attttctaca
     6181 aaatctacaa aacatttaaa gtaccctttt acctttaaat aatccaacat atatctaaat
     6241 gttaataata ttggtatacc tattactgtt gaaccaatta tacaggagat ataaactaat
     6301 acaggattta agtttagtgc aagacccata ggaattgccc ctctaagctc tacaattggt
     6361 atcatggata aaaatattaa atttacatat tccaatatat ttctccttat tataagtaat
     6421 ttaattcttt aattgagatt tgttttagtt ataaaataaa atctatctca atatgcattt
     6481 ttatttaata tccctttaaa tatagtaaaa aaaactattt ttacatcaaa taaaaatgtc
     6541 cagttctcta tgtaatataa gtcatattct attctttttt ctattgatgt atctcctcta
     6601 tatccattta cttgagccca acctgttatt ccgggtctta cttgatgttt tatcatatat
     6661 ctaggtattt catacttaaa cttgtctaca aaatatggcc tttctggcct aggacctact
     6721 attgacatat ctcctttaat gacattaaaa aattgtggta actcatctat acttgttttt
     6781 ctcattatcg aaccccattt ggtctttcta gaatcatttt ttgttgtcca cttagtaatc
     6841 tcttcttctt ctttctgtgt tttcatagat ctaaatttat acatatcaaa attttttcta
     6901 tttaacccaa ctcttgtttg cttatatatt attttccctg aagaagtcaa ttttatcatt
     6961 aatattgaaa acaacataat tggcaatgtt ataataatgc caattattga aaaaattata
     7021 tcaaatagtc ttttacatgc attattaaaa taattatcta atggtacatg tctagtatct
     7081 attattggaa atccatctaa atcatccata taaggttttg atggtacata attataataa
     7141 tatggaacta tatttgtttt tacacctgct ttttcacatt gttttattat ttctccaaat
     7201 ttataaaatt tttctgaatc aatagttata aatactatat ccacatgtgt tttttccaat
     7261 atagtttcta tttcatctat agttcctaaa attaatattt cttcaaatct atctaaatga
     7321 taaagatcat catctaaaca tcctataata ttatatcccc actgtttatt tttctttatt
     7381 tttccaatta attttttacc agtctctgta gctcctacta ctaaacaatg tttttgattg
     7441 aaccctttac ttctatactt tctcaatata ctccttaaca ctaccctact taaactagtt
     7501 aatattacat tatacattac aaataacata agaacaattc ttgaataatt tattaatttt
     7561 attatgaata gaattaatgt caatattaat gcacctataa tattagcatt aattatttct
     7621 tttatttctt tatataaatt acttgttcgt tttgcactat ataagtctaa aatattatat
     7681 aatataaaat acattacaac agaacaaata gctgttataa tatatccata cacacctatt
     7741 gaatttactc ctgctagtag attaaacttt gtataataag caagtataaa agatgataat
     7801 ataataatta aatcgattat catttgtata ttgtttaata acttttgatt ttcctttatc
     7861 ataaaaacac cttttttcta tcaaatatat tattgtataa ttttagcata ctttgatatt
     7921 tttttgtatt taaattaaga ttgacataaa aatacaaatt atttctagta aaaaattcaa
     7981 atatcactaa tacaaaaaat gtatatttat aatagatcca tatta
//
LOCUS       DAFAZV010000089         7775 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.092, whole genome shotgun sequence.
ACCESSION   DAFAZV010000089 DAFAZV010000000
VERSION     DAFAZV010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7775
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.092"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..1473
                     /locus_tag="KOU88_003785"
     CDS             <1..1473
                     /locus_tag="KOU88_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBK3213601.1"
                     /translation="SKALSDLSNVQSKLANMKIPDMNTKMASQFKTLQNEAGKLANKI
                     ETLGKSGYADTSKLQALSNSLKSIQNLNLKNLTSNQIQSEIQKLEQLKNKVKEVENAT
                     KNTKLDAKFNMNLSKVISDLNRLRQKCLELGQSTAGIDKLEKELMQLNGMPLGQKVKE
                     LDSIKSRLSNMKSNFTGLGTSVKATNGFFSDLYNSMRTYTLGNMIGMSITNGVRNIKT
                     TIVELDSALRDMMKVAPDNFEGTSEQLKNVKNEAISIGKDTARASEDIIQGASKALQT
                     GVKSVSDSLKIAKQSAVFANVGDLDQETADKYLTSVMSAYGGMTKALKPIKDTRVQIK
                     GMSKDYDNLTKFLDLSNYAGNNFAITTGDVGAALQRSASMLSSAGVSMEDSVALIVGG
                     NESVQNAEKVGTALKTIGINMSGIKASADSGKISLNKTAKTLQETAKINVLDKQTGQV
                     RDMMSILDELAEKWHSVGEDALTKNQKSGIAEAINFSRLI"
     gene            1783..>7775
                     /locus_tag="KOU88_003786"
     CDS             1783..>7775
                     /locus_tag="KOU88_003786"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213602.1"
                     /translation="MDNWNQVKKFQSAWLGGEVLGSASKENERFINSAEGKIIKLKES
                     LKQLVTDTISTDMFKTSLDGLSGITGILNGITKAADKMHVSLPVALAGLSSLFMTIKA
                     LGTGKPITNLGGSIFSAFQNNRKSVKFKDFERATKFTNQYTSAINKNTNASKNNAKSN
                     QVVNRTINSQNGIVGKYTSTTNSLKKATAKEIKINEDRTKSYEKYNQKLKVVSKSRKD
                     TISDGLGNIGKAFAGSSIVNFGKGIATTVGNSLVLTAAFAGVSLLAQAMENYANREEN
                     AYQARKKNIQASKQQINSYESQKVQLQALAEEYDNLSKKENKSKEDNNRLNELKQQIA
                     KIKPDAVIGTDENGIPILKGQVTDLIAEIDRAINAKERLMSYDKHDNAKTAAKKLNSP
                     SKDVNKTLEERMRESETGKLVKIEEDYTAEVEKNKKRQEKAIEKYNNSTGRARDKARN
                     ELMSAKAEEEKIYFKYDEMYRNQVDKIQGYSKEIGDGIFSNIKNKTLYSGLEGNDKSS
                     FAGLESLFDFSEVTPDTLVDTEQAVNKLLTAVRSGKVDVGDLSKTLKDANEEFARTQD
                     IEKYNQTIDKTAKSIAKATNTDANIWENLFGQVNPNGIKDMTSINTLLAKFGKTKLDL
                     ANGDKLAMQLQNQFDSIQNILDTTTITGDVKVDANILTDIKNTKEVPSQVKGMIDALL
                     GTGASTTDVLKFTMDVLMELQTGDPDINKLQNDLDSKFGKGKFTITPEILLSDDSGQA
                     NAEQIISNLKQRYEELPEEVITVIKANPTATLEEADSVKRIYDKFPKEVKTIIKEEGA
                     DEGGRKILDLTSKYAEVPSELKTKLEADGVGLEKAVEVSEIYKKVPAELKTYFIAEAG
                     EALYNSVNLKDALEHIPDEKITEIYLKQNDGKLGVQDLITSLDKIPLDKDVRINIYKA
                     LSDGDIDALGKAIESLPPDKRVEIIAEIEKAKDDIETISSSEIANKIFTIEVKDLASD
                     AIEWIQKKLKEINGDKNKKDPVKEAKESTKKVLKDKPNPKSVAFSRDKEAEKLVDDIL
                     NTPPTKQIELKLKKNEELRNTLNSFKQLEGRNDVKLKLESSGIETEQVKIFADIVKNL
                     PTNSTFTNKFITDNVDSLKNLKDYEAVQKWLMDNPTIAMDYSINLNGLDDFDKMKSIY
                     DGLEDKKDKKVFAEVIIKNPEKAEAFQKLYDNVPEETKSKVVSFAVENADELERATKL
                     YESTPDEQKNQVLNFMLNNEDKLYLIEQLYNDFPESKDIIANLIVNNPDALDEVENLN
                     ALDLDKDVKINIIKSLTNGDINSLIAEIEKLPPEKQVEVIAAIEGAIEGIDSVDKKTI
                     KDKWAKLKANNSAALETIRQTENKKLSDKSFTITAHLRTVGTLGGIASQFANNILGGL
                     KSNRKSVQSINSIETPQAIPANLSAQPRTSEPAPISDETPVTKPSLFSRAASRATSPV
                     KTLTEKFSRITKTPKIALDTKSIDAAVKYSIELLKELENAISKVADRISLLDKKMKYA
                     SGKDKLKYLEEQNALYKEELTLLDQKDKALNTQKNRLKDRLKKDYKYTFSDDDNLTSY
                     EEKLISLEKELEKLDKQSESDKGSKKSEERKKKIEEEKKVVEEYLKIAFTEIPKVADA
                     QQEVTNSLIESTRAAEEFKKELKEIAREAALTSAQKHVTEIQNEIDLIDILMKNAEGD
                     EKLDLIEKKKELLAKQAKEIKDVIKVYEDTAKELREGLSKEGFEFSADGKSITNYEQQ
                     LAFLKNNKDADKYKEIAENAKKYLDLLLKDLPDANKQIQQNKEEIEDLNKEIQDAYKD
                     QLKEAQSLQEKIRDMYKKELEERLKEIDKETKAKIDSLKKQQDAYNDSRKEAKYKDDY
                     EEQQDVISDLEKQIAIAERDSSLSGQKKLKDLQKQLKEEQKKLQDLVQDHVDDQVNDM
                     YDKESDRLQEEADKLKEELEKKYSDENLVDLINEAISSGKFVGLDGEVKKLQDAIIEY
                     INKYENGMLAMGSVTKQEWLDKLKEGKETLEDINDILDE"
BASE COUNT         3390 a          934 c         1386 g         2065 t
ORIGIN      
        1 tcaaaggctc tatcagattt atcaaatgtt cagtctaagt tggctaatat gaaaatacca
       61 gatatgaata caaaaatggc ttctcaattt aaaactcttc aaaatgaagc tggaaaatta
      121 gctaataaaa tagaaacatt gggtaagtct ggatatgcag atacatctaa actacaagct
      181 ttatcaaatt cattaaagtc aattcaaaat ttgaatctta aaaatctaac ttctaatcaa
      241 atacaatcag aaatacaaaa actagaacaa ttaaaaaata aagttaaaga agtagaaaat
      301 gctactaaaa atactaaatt agatgctaag ttcaatatga atctttccaa agtaatttca
      361 gatttaaata ggcttagaca aaaatgttta gaattgggtc aatcaactgc tggaattgat
      421 aaactagaaa aagaattaat gcaattaaat ggtatgcctc taggtcaaaa agtaaaggaa
      481 ttagattcaa taaaaagcag attaagcaat atgaaatcta atttcacagg attaggaact
      541 agtgtaaaag caacaaatgg attttttagt gacctatata attcgatgag aacttatact
      601 ttaggtaata tgataggtat gtctattaca aatggtgtaa gaaatattaa aacaactatc
      661 gttgaattag atagtgcttt aagagatatg atgaaagtag cacctgataa ttttgaaggt
      721 acaagtgagc aattaaagaa tgtaaaaaat gaagcaatat caatagggaa agatacagct
      781 agagcatcag aggatataat tcagggggca tctaaagctc tacaaactgg tgtaaaatcg
      841 gtatcagaca gtttgaagat agctaaacaa tcagcagttt ttgcaaatgt tggtgattta
      901 gaccaagaaa ctgctgataa gtacttaact agtgttatgt ccgcttatgg tggaatgaca
      961 aaagcattaa aaccaattaa agatactaga gttcaaatca aaggaatgag taaagattat
     1021 gataatctta caaaatttct tgatttatcg aactatgcag gtaataattt tgcaataaca
     1081 actggcgatg taggagctgc attacaaaga agtgcaagta tgttatcatc agcaggcgtt
     1141 tcaatggaag actctgttgc tttgatagtt ggaggaaatg aatctgtaca aaatgctgaa
     1201 aaagtaggta cagcactcaa aacaattggt ataaacatga gtggtatcaa agcttcagca
     1261 gattcaggaa aaatcagcct caataaaaca gcaaaaactt tacaagaaac agcaaaaata
     1321 aatgtgttag ataagcaaac tggccaagta agagatatga tgtcaatttt agatgagttg
     1381 gcagaaaagt ggcatagtgt tggcgaagat gccttaacta aaaatcaaaa aagtggtatt
     1441 gccgaagcga ttaattttag tcgccttata tagtaatata taatgataaa ctcctttaat
     1501 tgctggaaac tcccgttagg cttttagtac caaagtgtga aaaactaaaa gatagggaca
     1561 atcagcagcc aaaactcaat gagagtaagg ttcaacgact aggttataaa ccgtacacta
     1621 taagctattg atagtggaaa tggggagcat ccttatagga tgaagatata gtctcatcta
     1681 tatggaaaca tatagcagtt cataagagaa cgagttaagt atagcgaact taattgaaga
     1741 ttttgttcag gtaaaaacca cataaatact ttcatggctg tcatggataa ttggaaccag
     1801 gtaaaaaaat tccaaagtgc atggctgggt ggagaagtgc taggtagtgc cagtaaagag
     1861 aatgagagat tcataaattc agcagaaggt aagattataa aattaaaaga aagtcttaaa
     1921 caattagtta cagatactat atctacagat atgtttaaga ctagtttaga tggattatct
     1981 ggtattacag gaattttaaa tggtataact aaagcggctg acaaaatgca tgtttcgctt
     2041 cctgtagccc tagcaggttt atcgtcttta tttatgacaa ttaaagcatt aggtactggt
     2101 aaaccaatca cgaatttagg aggaagtata tttagtgcct ttcaaaacaa tagaaaatct
     2161 gttaaattta aagactttga aagagctaca aaatttacta atcaatatac aagtgctata
     2221 aataaaaata ctaatgcttc aaaaaacaat gctaaatcaa atcaagttgt taatagaact
     2281 ataaatagtc aaaatggcat tgtaggaaaa tatacatcaa caaccaacag tttaaaaaag
     2341 gcaacagcta aagaaataaa aataaatgaa gacagaacaa agtcatatga aaaatataat
     2401 caaaaattaa aagttgtttc taaaagtaga aaagatacaa taagtgatgg gcttggtaat
     2461 attggtaagg catttgcagg gagtagcatt gtaaattttg gtaaaggtat agcaactaca
     2521 gttggaaatt ctttagtttt aactgctgca tttgcaggtg taagtctatt agcacaagct
     2581 atggagaatt atgcaaatag agaagaaaat gcttatcaag ctagaaagaa aaatattcaa
     2641 gcttcaaaac aacaaattaa ttcatatgaa agccaaaaag ttcaattaca agcacttgca
     2701 gaagaatatg ataatttatc taaaaaagaa aataagtcta aagaagataa taatagatta
     2761 aatgaactaa aacaacagat tgcaaaaata aaaccagatg cagttatagg aacagatgaa
     2821 aatggtatac ctattttaaa aggtcaggtt actgatttaa ttgctgaaat agatagagct
     2881 attaatgcaa aagaaagatt gatgtcctat gataaacatg ataatgcgaa aactgctgct
     2941 aaaaaattaa attctccaag taaagatgta aataaaactt tagaagaaag aatgagagaa
     3001 agcgaaactg gtaagcttgt aaaaatagaa gaagattata cagcagaagt tgaaaagaat
     3061 aaaaaaagac aagaaaaagc aatcgagaaa tataataatt caactggtag agcaagagat
     3121 aaagccagaa atgaattaat gtcagctaaa gcagaagaag aaaaaatata tttcaaatat
     3181 gatgaaatgt atagaaatca agtagataaa attcaagggt attcaaaaga aataggagat
     3241 ggaatatttt ctaacattaa gaataaaact ctttatagtg gattagaagg caatgataag
     3301 tctagttttg ctggacttga aagtttattt gattttagtg aagttacacc agatactcta
     3361 gtagacacag aacaggcagt caacaaattg cttactgctg ttagaagtgg gaaagttgat
     3421 gtaggagatt tatctaaaac tcttaaggat gcaaatgaag aatttgctag aacacaagat
     3481 atagaaaaat ataatcaaac aatagataaa acagctaaga gtatagctaa agcaactaac
     3541 acagatgcta atatatggga aaatttattt gggcaagtaa atccaaatgg aattaaagat
     3601 atgacatcta taaatacatt attagctaag tttggtaaaa caaaactaga tttagcaaat
     3661 ggtgataaac ttgcaatgca actccaaaat caatttgata gtattcagaa tatattagat
     3721 acaactacaa taactggaga tgtaaaagtt gacgcaaata tattaactga tattaagaat
     3781 actaaggaag ttcctagtca agtcaagggc atgatagatg ctctattagg gacaggagca
     3841 agtactactg atgtattgaa attcactatg gatgtgttaa tggagttaca gactggcgac
     3901 ccagatataa ataaacttca aaatgattta gacagtaaat ttggtaaagg taaatttact
     3961 ataactccag aaatactttt gagtgatgat tcaggtcaag ctaatgcaga acaaataata
     4021 agtaacttaa agcaaagata tgaagagctt ccagaagaag taatcacagt cataaaagct
     4081 aatccaactg caacattaga agaagctgat tcagtaaaaa gaatttatga taaatttcca
     4141 aaagaagtaa aaactatcat aaaagaagaa ggagcagacg aaggcggtag aaaaatatta
     4201 gatttaacat ctaagtatgc cgaagtacct tctgaactca aaactaaatt agaagctgat
     4261 ggagttggac tagaaaaagc tgttgaagta tcagagatat ataagaaagt acctgcggaa
     4321 cttaaaacat attttatagc agaagcggga gaggctttgt ataattctgt taatttaaaa
     4381 gatgccttag aacatatacc tgatgagaaa attacagaaa tatatttgaa gcaaaatgat
     4441 ggtaaattag gggttcagga tttaataaca tcattggata aaattccttt agataaggat
     4501 gtaagaataa atatatacaa agccttatct gatggagata tagatgcttt aggcaaagct
     4561 attgaaagtt taccaccaga taaacgagta gaaataattg ccgaaataga aaaagctaaa
     4621 gatgatattg agactattag ttcttctgaa atagcaaata aaatttttac tatagaggtt
     4681 aaagacttag catcagatgc tattgaatgg attcaaaaaa aattaaaaga aataaatggt
     4741 gataaaaata agaaagaccc tgttaaagaa gctaaagaat ctactaaaaa ggttttaaaa
     4801 gacaaaccga atcctaaaag tgttgcattt tcaagggata aagaagcaga aaagcttgta
     4861 gatgatatat taaatacacc tccaacaaaa caaattgaac ttaagttaaa gaaaaatgaa
     4921 gagcttagaa atactttaaa ttcatttaaa caacttgaag gaagaaatga tgtaaaatta
     4981 aaattagaat catcaggtat tgagactgaa caagttaaaa tttttgctga tatagtaaaa
     5041 aatcttccaa caaattcaac ttttactaat aaatttataa ctgataatgt tgatagtttg
     5101 aaaaatctaa aggattatga agccgtacaa aaatggctta tggataatcc aactatagct
     5161 atggattata gcataaattt aaatggttta gatgattttg ataaaatgaa atctatatat
     5221 gatggattag aagacaaaaa agataaaaaa gtatttgctg aagttataat taaaaatcca
     5281 gaaaaggctg aagcatttca aaaactatat gataatgttc cagaagaaac aaaaagtaag
     5341 gttgttagct ttgctgtaga aaatgcagat gaacttgaga gagctacaaa actatatgaa
     5401 tcaacaccag atgaacaaaa aaatcaagtt cttaatttta tgttaaataa tgaagataag
     5461 ttatatttaa tagaacaact ttataatgat ttccctgaaa gcaaagacat tatagctaat
     5521 cttatagtaa ataatccaga tgcattagat gaagttgaga atttaaatgc tttagaccta
     5581 gacaaagacg taaaaataaa tataataaaa tcactaacta atggagatat taattcatta
     5641 attgctgaaa tagaaaaatt acctcctgaa aaacaagttg aggtaattgc agctattgaa
     5701 ggagctattg agggcataga tagtgttgat aaaaaaacaa taaaagacaa gtgggctaaa
     5761 cttaaagcga ataattctgc tgctttagaa acaattcgtc aaactgaaaa taaaaaacta
     5821 agtgataaga gttttacaat aacagcacat cttcgtacag tagggactct aggaggaatt
     5881 gcttctcaat ttgcaaataa tatattaggt ggattaaaga gtaatagaaa aagtgtgcaa
     5941 tccataaatt ctatagaaac tccacaagca attccagcta atctatcagc ccaacctaga
     6001 acgtcagaac cagcaccaat aagtgacgaa actcctgtaa caaaaccatc tctattctca
     6061 agagcagcat caagagccac atctccagtc aaaactctta cggagaaatt ctctcgtata
     6121 actaaaactc ctaaaatagc attagataca aaatctattg atgcagcagt aaaatatagc
     6181 attgagttac taaaagaatt agaaaatgcg atatctaaag ttgcagatag aatatctctt
     6241 ttagataaga aaatgaaata tgcaagtgga aaagataaac ttaaatatct tgaagaacaa
     6301 aacgctttat ataaagaaga actaacattg ttagaccaaa aagataaggc acttaatact
     6361 caaaagaata gactaaaaga tagacttaaa aaagattata agtacacttt ttcagatgat
     6421 gataacttaa ctagttatga agaaaaatta atatcattag aaaaagaatt agagaaatta
     6481 gataagcaat cagagagcga caaaggtagt aaaaagagtg aagaacgtaa gaagaaaata
     6541 gaagaagaaa aaaaggttgt tgaagaatat ttaaagattg cttttactga gataccgaaa
     6601 gttgcagatg ctcaacaaga agtaacaaat tctcttatag aatcaactag agcagcagag
     6661 gaatttaaaa aagaattaaa agagattgct agggaagctg ctttaacttc agctcaaaaa
     6721 catgttactg aaatacaaaa cgaaatagac ttaatagaca ttcttatgaa aaatgctgaa
     6781 ggtgatgaaa agttagactt aattgaaaag aagaaagagt tattggccaa acaagctaag
     6841 gaaattaaag atgttattaa agtctatgaa gatactgcaa aagagttaag agaagggtta
     6901 tcaaaagaag gatttgaatt ttctgctgat ggtaaaagca taacaaatta tgagcaacaa
     6961 ttagcgtttc taaaaaataa taaagatgca gataaataca aagaaatagc agaaaatgct
     7021 aagaaatatt tagatttact tcttaaagat ttacctgatg ctaataaaca aattcaacaa
     7081 aataaagaag aaatagaaga tttaaataaa gagattcaag atgcttataa agaccagctt
     7141 aaagaagctc aaagcctaca agaaaaaatt agagacatgt ataaaaaaga gcttgaagag
     7201 agacttaaag aaatagataa agaaactaaa gctaaaattg attctcttaa aaagcaacaa
     7261 gatgcttaca atgattcaag aaaagaagcc aaatataaag atgattatga agaacaacaa
     7321 gatgtaataa gtgatttaga gaaacaaata gcaatagctg aaagagatag ttctttaagt
     7381 ggtcagaaga aacttaaaga tttacaaaaa caattaaaag aagaacagaa gaaattacag
     7441 gatttagtac aagaccatgt ggacgaccaa gtcaatgata tgtatgataa ggagtctgac
     7501 agactacaag aagaagcaga taaattaaaa gaagagttag agaaaaaata ctcagatgaa
     7561 aatttagttg atttaattaa tgaagcaatt tcaagcggta agtttgtagg tcttgatgga
     7621 gaagttaaga aacttcaaga tgctattatt gaatacataa ataaatatga aaatggtatg
     7681 ttggcaatgg gttctgtcac taagcaggaa tggctcgata agctaaaaga aggtaaagag
     7741 acattagaag atattaacga catattagat gaatt
//
LOCUS       DAFAZV010000090         7715 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFAZV010000090 DAFAZV010000000
VERSION     DAFAZV010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7715
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.093"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            322..1623
                     /locus_tag="KOU88_003787"
     CDS             322..1623
                     /locus_tag="KOU88_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3213603.1"
                     /translation="MGKSKDVEIEKSILGTILLDNKLSYKLDELNENMFMNDICLEIF
                     KIMKELKKENIVIDVATVKSKIDRKSLAIKTSDVTNLITWGQNFGLDGHIKILKENLA
                     RRSINQNCQNLLHSLNLGENIDTCIYKFESNIKEILDKDTYENDDVNSIAGKVLDFLE
                     NKKDIGFKFGIKLLDTTIGGLFKGELTTIAAKSGVGKTALALQIMLNSFKQGKKTLFI
                     SREMTSEQVFMRNICRVTGVSTRNMKSKEIDENDWKLIVNAIGDLSENNLIYINDKID
                     TISAIRKRIRQVKPDLLIVDYVQLLTSQKSMDKREREVATFSRELKNMTLDFNIPVIQ
                     LSQLNDEMKDSRPYGDRPMRDSKAIYHDSNNVVYIHQLKGSDYEEAVRDIGESEEAVR
                     ASEYRGIKMVDLIVAKCRDGQTRHKHFCYFGDKLHFQELNY"
     gene            1699..1974
                     /locus_tag="KOU88_003788"
     CDS             1699..1974
                     /locus_tag="KOU88_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK3213604.1"
                     /translation="MLELRKIIELLEEHKIEVSIPKELHKYSLLEYLELCQQSGGTYF
                     YIKTLEGALKEARNELMIKLFNGKNYMELARMFEMSVINVRHIVRKK"
     gene            3309..3539
                     /locus_tag="KOU88_003789"
     CDS             3309..3539
                     /locus_tag="KOU88_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3213605.1"
                     /translation="MSNKKKKYANILANECVACGSCIKACPRSAISVPCGISAKINRD
                     LCVGCGICEKICPASVIEIITILKEEEGKCHE"
     gene            3532..4113
                     /locus_tag="KOU88_003790"
     CDS             3532..4113
                     /locus_tag="KOU88_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK3213606.1"
                     /translation="MNNKKHWYDYLWIFSSIYLILGFVNIIFAWIGLICFFVPLAISI
                     VKGNKAYCNKYCGRGQLFNLLGNKLKLSRNRDIPKFIRSKWFRYGFLTFFMVMFANML
                     FSTYLVFEGSRNFKEVVTLLWTIKMPWQWAYHGTLVSPWVVQFAFGFYSVMLTSTVLG
                     LITMILFKPRSWCVYCPMGTMTQMICKAKSKSV"
     gene            complement(4692..5369)
                     /locus_tag="KOU88_003791"
     CDS             complement(4692..5369)
                     /locus_tag="KOU88_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK3213607.1"
                     /translation="MISQNEIDILTHSLPFWDKLTDLQKELLISSANTSHYKKGNPVH
                     CGDSDCIGILIIKSGTVRTYILSDEGREVTLFRLDDGDVCILSASCILKTITFDVYVD
                     AETDCDIIQISSSVFAKLSTENIHAELFSYKLATERFSDVMWAMQQILFMSFDKRLAS
                     FLIDEIAKNGSSTINMTHEQIAKYMGSAREVVSRMLKYFAREGIVSLSRGGIKVLDKD
                     KLRSLTL"
     gene            complement(5558..6922)
                     /locus_tag="KOU88_003792"
     CDS             complement(5558..6922)
                     /locus_tag="KOU88_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK3213608.1"
                     /translation="MKESNKRIELLGSAPISKALLSMGLPTMIGMMITALYNLVDAYF
                     VGGLGTSQMGAISVAFPLGQLVVGLGLLFGNGAASYVARLLGHGDNEKAGKVVSTSIY
                     SSIIVGTLVIIVIMIFLNPILKLLGATKSIMPYAISYASIYVVSSIFNIFNVTMTNIV
                     TSEGAAKTTMCAMLLGALLNMILDPIFIYTFGLGVRGASIATAISQIASTLVYVGYIL
                     SKKSIFSFRINECCFSKEIFSEILKIGIPTLIFQLLTSLAITLTNMEATKYGDSVIAG
                     MGAVTRITSLGSLVVFGFIKGFQPIAGYNFGSKNYDRLHIAIKTSILWTTVFCVVLGL
                     ILILFPKSIISQFTSGDILLIENGSKALRANGFSFMLFGFYTVYSTLFLALGKAKEGG
                     FLGMCRQGVCFIPIILIIPVFYGLNGILYAQPIADLMAAIIAGFMSIRLHKELNLLKI
                     NGMH"
     gene            7050..7571
                     /locus_tag="KOU88_003793"
     CDS             7050..7571
                     /locus_tag="KOU88_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK3213609.1"
                     /translation="MATIDLIVLGIVKQQPKSAYDIQKAVEYRNISRWVKISTPSIYK
                     KVIQLEQKGYIESKTVKNGKMPEKAVYSLTELGETHFLDLMFDTSSKPINILLDFNAV
                     IVNLNSLTPEKQKLCLNNIEENVQELKKTIEENISIKTEVPDTAKAVLEQQLVLAQAL
                     ETWINSLKDNMGN"
BASE COUNT         3015 a          880 c         1328 g         2492 t
ORIGIN      
        1 gagtaatgaa ttatattgaa cgatatatca ataattggca gtaagttata tcaaataaga
       61 tattactatc gagtaatgaa ttatattgaa caatatatta ataattggca gtaagttata
      121 tcaaataaga tattgctatt atgtagtaaa ttatataaaa caatgtatca gaataaatag
      181 tatattaata atttgtagta tatcatgacg aataatacag tcataacaaa tagtgagtca
      241 taacaaataa tgtatttata attgataatg tatttaaaaa tcaaaatata aaaacttata
      301 aggaaagaga gattaattta tatgggtaaa tcaaaagatg ttgaaataga gaagtctatt
      361 ttaggcacaa ttcttttaga caataaatta agctataagc tagatgaatt aaatgaaaac
      421 atgtttatga atgatatatg tcttgagata tttaaaatta tgaaagaact taaaaaagaa
      481 aacatagtga ttgatgtggc cactgtgaaa tcaaagatag atagaaaatc tctagcaata
      541 aaaacaagtg atgtgactaa tctaattact tggggtcaga attttggtct tgatggtcat
      601 attaaaattt taaaagaaaa tttagctaga agaagcataa atcaaaactg ccaaaacctt
      661 ttacacagcc taaaccttgg agaaaatatc gatacttgta tttacaaatt tgaaagtaat
      721 ataaaggaga ttttggacaa ggatacttat gaaaatgatg atgtaaatag tatagcaggg
      781 aaggtgcttg attttttaga aaacaaaaaa gatattggat ttaaatttgg tataaaatta
      841 cttgatacca ctataggagg tctttttaaa ggagagctaa ccacaatagc agctaaatcg
      901 ggggttggga agactgcttt ggcacttcaa ataatgttaa attcatttaa gcaaggtaaa
      961 aaaactttat ttataagtag agaaatgacc agtgagcaag tatttatgag aaatatatgc
     1021 agagtaactg gtgtaagtac aaggaatatg aaatctaaag aaatagatga aaatgattgg
     1081 aaacttattg taaatgcgat aggtgattta agcgaaaata acttaattta tatcaatgat
     1141 aagatagata caattagtgc aattagaaag aggataaggc aggtaaagcc agatttatta
     1201 atagtggatt atgtgcaact ccttacatct cagaaaagca tggataagag agaaagggag
     1261 gtagctactt tttcgagaga acttaaaaat atgactttag attttaatat acctgtaatc
     1321 caattaagtc agttaaatga tgaaatgaaa gattcaagac cttatggaga tagacctatg
     1381 agggatagca aagccatcta ccacgatagc aacaatgtgg tttatataca tcaattaaag
     1441 gggagtgatt atgaagaagc agtgagagat attggagaaa gtgaggaggc agttagagca
     1501 tcagaataca ggggaattaa gatggttgat ttaatagttg cgaagtgtag agatggacag
     1561 actaggcata agcatttttg ttactttggg gataagttac attttcaaga actaaattat
     1621 taggtcaata aagtagtaat aacaagctta ttaaaagtcg ggaaatagca aatagattat
     1681 aaaatatgag gtgaaaatat gttggaatta agaaaaatta tagaattact tgaagaacac
     1741 aagatagaag taagtattcc aaaggagtta cataagtata gtttattgga ataccttgaa
     1801 ttgtgtcaac aaagtggggg aacatatttt tatattaaaa cactggaagg ggctttaaaa
     1861 gaggctagaa atgagcttat gattaaattg tttaatggga aaaattatat ggaattagcg
     1921 aggatgtttg aaatgagtgt tattaatgtc aggcatattg ttagaaaaaa atagatattt
     1981 ttggagaata caagtgtgat atacttctga aatagaagtt attataagag gagtataagt
     2041 gtgattaaca acatgatttt gtgaataaaa ttgaggatat atatgagtta aatgtgtgat
     2101 taataaggta agattgtgta taagattatg agtatttaaa aggaggggct ataattaata
     2161 gtgtagagtt gtgtgtttgc ttaagattat ataataattt aatagattaa actatactaa
     2221 taaggtaaaa tcgtgtgttt agttaaagct tattataaaa tcttgatatg tgattaatga
     2281 tgcaatatgt gaataaagtt aagattataa tagatttaac ctgtggctaa tagaataaaa
     2341 ttgtgaataa agttaagatt ataataggtt taaattgtga ctaatagagt aagagtgtaa
     2401 atagagataa acttcaatat gagcttaacc tatgattaat agagtaagaa tgtaaataga
     2461 gataaacttc aatatgagtt taacttgtgg ctaatagagt aagagtgtaa atagagataa
     2521 acttcaatat gggtttaact tgtggttaat agagtaaggt gtaactaaag ataaacttca
     2581 atatgagctt aacctatgat taatagagta agaatgtaaa tagagataaa cttcaatatg
     2641 agtttaactt gtggctaata gagtaagagt gtaactaaag ataaacttca atatgggttt
     2701 aacttgtggt taatagagta agaatgtaaa tagagataaa cttcaatatg agcttaactt
     2761 gtgattaata gagtaagagt gtaaatagag ataaacttca atatgggatt aacttgtgat
     2821 taatagagta agagtgtaac taaagataaa cttcaatatg agcttaacct atgattaata
     2881 gagtaagaat gtaaatagag ataaacttca atatgggttt aacctgtggt taatagagta
     2941 gggtgtaact aaagataaac ttcaatatga gtttaacttg tggctaatag aataagattg
     3001 tgaataaagt tatagtttta gatgggtatt aacctgttac taatagaata tgattaggtg
     3061 taaaattata gagctgcata agaaaatatt atagatatat taaatattag ataataaata
     3121 tttatataga tacacaaaag aaaaggcgat atgaagctaa acttaatgac ttcatatcgt
     3181 tttttatttg aaactccttt gtatttagag tgtgattttt aatattgagg ttttatgtga
     3241 ttaagtcaca gataaaaagt aagtatcttg atataattct tatagattaa taatataggg
     3301 aggttattat gtctaataaa aaaaagaagt atgcaaatat tttagcaaat gagtgcgttg
     3361 cttgtggtag ctgtataaaa gcatgtccaa gaagtgctat ctcagttcca tgtggcatta
     3421 gtgcaaaaat taatagagat ttatgtgttg gatgtgggat ttgtgaaaag atatgtccag
     3481 catctgtaat tgagattata acaatattaa aagaggaaga aggtaagtgt catgaataat
     3541 aaaaaacatt ggtatgacta tttatggatt ttttcttcaa tatatttgat attgggattt
     3601 gtaaatatta ttttcgcttg gattgggcta atttgtttct ttgttccact agctatttct
     3661 attgttaagg gaaataaagc ttactgtaat aagtattgtg gaagagggca actgtttaat
     3721 ttgcttggaa ataaattgaa gctgtcaaga aatagagata ttcctaaatt tattagaagt
     3781 aagtggttta gatatgggtt tttgacattt tttatggtaa tgtttgccaa tatgcttttt
     3841 tcaacttatt tagtgtttga aggaagtaga aattttaaag aagtagtgac tttgttgtgg
     3901 actataaaaa tgccttggca atgggcgtat catggaactt tagtttcacc ttgggtggta
     3961 cagtttgcat ttggttttta tagtgttatg cttacatcaa ctgttcttgg tttgattact
     4021 atgatattgt ttaaacctcg ttcatggtgt gtttattgcc ctatgggtac tatgactcag
     4081 atgatatgta aggcaaagag taagtctgta tagaaaggcc ttatgtgata tttacagttt
     4141 tgttcaagta gagatgagta gtaggtttga atatatatga caaatatatg agtatagggg
     4201 catagattta gtttgtgtaa ggtaaactga tttatgcttc ttttttatgt cttagattat
     4261 tggctaagtg gaaacaatga atttagatat taagaattat tcagttattt gaagaaaata
     4321 gaataataat taacattata ttaatggata ttcattacat ataagccagt taatagcaag
     4381 atttatttaa tatgatatag gtcaagtatt taaactaaat aaggtcatga caattaatat
     4441 aagtatagat ataaaaagat tagaagttat aacttataaa aggtattcta tataaatagt
     4501 atggggaaaa tagtcaaatt aacttattag aaacaaaaaa tatacataaa aaataaatgt
     4561 aaatatcaaa taagatacta tatcaaaata gatataagta tcttttttat tattgaaatt
     4621 atgaaaatat atttgatttt acacaaaaaa gagtgcctca tgaactaaaa agttcatttt
     4681 gagacacact tttacagtgt caaagaacga agtttatcct tatccaatac ctttatacca
     4741 ccacgagata aagacacaat accttctcta gcaaaatatt tcaacattct cgatacaact
     4801 tctctggcac tacccatata cttagcaatt tgctcatgag tcatatttat agtgctactg
     4861 ccatttttag ctatctcatc aattaaaaaa gatgccaaac gcttatcaaa actcataaaa
     4921 agaatttgtt gcatagccca cataacatca gaaaaacgtt cagtagctaa tttatatgaa
     4981 aataactctg catgaatatt ttctgtagat aattttgcaa aaacagagga actaatctgt
     5041 ataatatcgc agtccgtttc agcatctaca tagacatcaa aagttattgt ttttagaata
     5101 caggaagctg ataaaataca tacatctcca tcatcaagtc ggaacagtgt aacctctcga
     5161 ccttcatctg aaagtatgta tgtacgcact gttccagatt ttataatcaa aataccaata
     5221 cagtcactat caccacaatg tactggattc ccttttttgt aatgcgaggt atttgctgaa
     5281 gaaattaata attctttttg taagtcagta agtttatccc aaaaaggcaa gctatgtgta
     5341 agtatatcaa tttcattttg tgaaatcata caatatctcc tttcttaaat tgttataatc
     5401 ccatgataca agtgaataga taaattgaca agtagtttgt taagaggatt atttagtcag
     5461 atagtaatag tatgatttat gtagaaaaaa tatgataata tatattcttg ctattaatga
     5521 gaaagtaata tgttttgatg atagtaggtt tgtataacta atgcataccg tttattttta
     5581 aaagattaag ttccttatgt aaccttatag acataaaacc agcaattata gcagccatca
     5641 aatcagctat tggttgtgca tataagatac catttaaccc atagaataca ggaataatca
     5701 aaattatagg gataaaacag acaccttgtc tacacatacc taaaaatcca ccttcctttg
     5761 cttttcctag tgcgaggaat aatgtagaat acactgtata gaatccaaat agcataaatg
     5821 aaaacccatt tgccctaaga gctttactac cattttctat taataaaatg tcaccacttg
     5881 taaattgtga aattatagat tttgggaaga gtatcaatat aagaccaagc actacacaaa
     5941 atactgtagt ccataatatg gaagttttta ttgctatatg taatctatcg tagttctttg
     6001 aaccaaaatt ataaccagca attggttgga aaccttttat aaaaccaaat acaacaagac
     6061 tacctaaaga cgttattcgt gttacagcac ccattccagc tatcacagaa tcaccatact
     6121 ttgtagcctc catattagtt aatgtaatag caagactagt caataattga aatattaagg
     6181 taggtatgcc aatttttagg atttctgaaa aaatttcttt tgaaaaacag cattcgttaa
     6241 ttctaaaact aaatatactt ttcttgctta aaatatatcc tacataaaca agtgttgaag
     6301 caatctgtga gatagctgtt gcaatagaag caccccttac ccccagacca aaagtataaa
     6361 tgaatatcgg gtctaaaatc atattaagca aagcacctaa taacatagca cacatagttg
     6421 ttttagcagc tccttcactt gtgacaatat tagtcatagt gacattgaat atattaaaaa
     6481 tagatgacac gacataaatg ctagcataag atattgcata aggcataata ctttttgtag
     6541 ctcctaacaa ttttaaaatt ggattgagaa aaatcataat cacaataata actaatgtac
     6601 ccactataat actactgtaa atagatgtac ttaccacttt tcctgctttt tcattatcac
     6661 catggcctaa aagtctggca acatatgaag cagctccatt tccaaacaat aatcctaatc
     6721 ccacaacaag ctgacctaat ggaaatgcaa cggatatagc tcccatttga cttgttccaa
     6781 gtccacccac aaagtatgca tcaaccaaat tgtataatgc agttatcatc atacctatca
     6841 tggtaggtaa tcccatagat aacaatgctt ttgagattgg ggcagaccct aataattcaa
     6901 ttcttttgtt actttctttc atacttaaca ctcctcttct attgacatta agtctaaatt
     6961 ataatactat aaattatagt aagtatggaa aatagtacta taatttatag tatttgtcaa
     7021 tagtaagaaa actaaaggag atgattttta tggctacaat agatttaatt gtattgggaa
     7081 tagtaaagca acaacccaag agtgcttatg atattcaaaa ggcagtggaa tacaggaata
     7141 tatcacgttg ggttaaaata agtacaccat caatttataa aaaagtaatt caattagaac
     7201 aaaagggata tattgaaagt aaaactgtga agaatggaaa aatgccagaa aaagcagttt
     7261 attcattaac tgaattaggt gagacacatt ttttagattt aatgtttgat acatctagca
     7321 aaccaataaa tattctttta gattttaatg ctgttatagt aaatttaaat agccttacac
     7381 cagaaaaaca gaaattatgt ctcaataata ttgaagagaa tgttcaagag ttaaagaaaa
     7441 ctattgagga aaatataagt ataaagacag aagtaccaga cacagcaaaa gcagtgttgg
     7501 agcaacagtt ggtgctagca caagcattgg aaacctggat aaattcttta aaagataata
     7561 tgggaaatta gaattagaga agctaactta ataatcatta aacaaaaacc agcatattta
     7621 ataatgagat attagaaaaa ataaaacaaa tgatataaac tgaaaagtat atttaaaata
     7681 aagctcactt aattgaggga gaatgttaaa ctttt
//
LOCUS       DAFAZV010000091         7651 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFAZV010000091 DAFAZV010000000
VERSION     DAFAZV010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7651)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7651)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7651
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.094"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..1267)
                     /gene="hflX"
                     /locus_tag="KOU88_003794"
     CDS             complement(<1..1267)
                     /gene="hflX"
                     /locus_tag="KOU88_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBK3213610.1"
                     /translation="MDMAKKGITVGLNINNKSEDFNELMIELENLCSACDIDVVGSIT
                     QNAKQVNRAFYIGTGKVEEILNLIKKENIEIVIFYNELSTSQLKNLEEKLNCEIIDRT
                     ALILDIFAQRAKTREAKLQVEVASLKYMLPRLIGSNENLGRQSGGVGTKNRGSGEKKL
                     ELDRRRIEEKITSLNRELDDLKFQRETQRSMRRKSNLPNVALVGYTNAGKSSIMNKLV
                     DIFKNSEEKKVFEKNMLFATLETSVRNIVLANNKEFLLSDTVGFVSNLPHDLVKAFRS
                     TLEEACEADVLLHVIDISNPSYKSHIKVTEDTLKQIGADGIPMIHVYNKIDLIDVEVL
                     DRILDSIDKEGIFVSVKKDINIDKMIKCICDSIFKDYVRCKFLIPYDKGHVVSYFNEN
                     TSIINTEYREDGAILDVECSNIEYNKYKKY"
     gene            complement(1986..3818)
                     /locus_tag="KOU88_003795"
     CDS             complement(1986..3818)
                     /locus_tag="KOU88_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213611.1"
                     /translation="MSRMGRGPMGKSMGAGQKANDFKGTMRKLIAYLSKFKISIILVI
                     VFAIGSASFSIVGPKILGKATTKIFEGLVSKVSGGNVGIDFNAIGKILTFLLFLYLIS
                     ALFSFIQGFIMSGISQKVSYNLRKEISAKLDRLPMKYFDTKTHGEILSRITNDIDTLN
                     QSLNQSMTQLITSVTTMIGVLIMMLSISGIMTLVAVLILPISMFVISRIIKKSQKYFR
                     YQQEYLGNVNGQVEETYSGQTIVKAFNREDEVIEEFDKLNDSLYNSAWKSQFLSGIMQ
                     PLMMFIGNLGYVMVSILGGWLAIKKTIEVGDIQSFIQYVRNFTQPMTQIAQVANLLQS
                     TAAASERVFEFLEEEEEVQIVENAVSIDGLEGKIDFENVNFGYNPNKTIINDFSVNVK
                     PGQKVAIVGPTGAGKTTIVKLLMRFYDVNSGSILIDGHNIKDFNRSELREMFGMVLQD
                     TWLFSGSIMENIRYGKLNATDEEVIEAAKSAHVHRFIKTLPDGYKMKLNEEASNVSQG
                     QKQLLTIARAILADPKILILDEATSSVDTRTEVLIQKAMDNLMEGRTSFVIAHRLSTI
                     RDADMILVMNEGDIVEQGNHEELLKKGGFYANLYNSQFEEDEAM"
     gene            complement(3811..6057)
                     /locus_tag="KOU88_003796"
     CDS             complement(3811..6057)
                     /locus_tag="KOU88_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011009877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213612.1"
                     /translation="MFKLIKYLKKSALSIVIIVCLLVIQAVCDLSLPEYTSNIVNVGI
                     QQGGVENSVPSVIRESELNKITLFMDKSSKDKVLDNYTLLNKKDYVKYKDKYPGLKDE
                     SLYELNTKDKDTIDDLNVIFGKAILIVSGLEGDSKEVKAMKAQLMSKLPPQATQSGDV
                     DIFKLLSAMPKEQLDTLTKEMSKGFESMPESMITQSSVSYVRSEYEKIGIDTEKTQNN
                     YILFTGAKMLGIAMISMVATITVGFLAARVAASVGRNLRSGVFRKVMSFSNTEMNEFS
                     TASLITRSTNDIQQIQMLMVMLLRIVFYAPIMAIGGVIKVLNTNTSMAWIIAVAVVAI
                     LSLIVVLFSVVMPKFKLVQKLVDKLNLVSREIITGIPVIRAFSTEKHEEERFDKANKN
                     LTKTNLFVNRVMTCMMPAMMLIMNLITVLIVWRGAYSVDSGAMQVGDMMAFIQYTMQI
                     IMSFLMISMVSIMLPRASVSATRIDEVLVSDISIKDPEKSEAQEFKEDKKGLVEFKNV
                     SFMYPDAEEPILTNISFTAKPGETTAFIGSTGSGKSTLINLIPRFFDVTEGEILLGGV
                     NIKNVSQHDLREKIGYVPQKGVLFSGTIESNLKYGRKDATDEEMRTAAEIAQATEFID
                     SKPEAFKTEISQGGTNVSGGQKQRLSIARAIAKNPEVYIFDDSFSALDLKTDAALRKA
                     LKSKTAESTVLIVAQRISTILNAEQIIVLNEGEIVGIGTHKELLKNCEVYEQIALSQL
                     SKEELANE"
     gene            complement(6125..6586)
                     /locus_tag="KOU88_003797"
     CDS             complement(6125..6586)
                     /locus_tag="KOU88_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3213613.1"
                     /translation="MNSNSEEKLNDVFLQLMRIYFIRTHFYFDKLGLYHGQPQILFSL
                     KMKDGQSQKELADKRKVKASTTTVMIKRMEKAGLVERKQDEKDQRVSRIFLTDKGLEI
                     CNKVEEFNKELEREFFLGFSEEEKIVLRRLLMQVRDNLKAGCHKHEDEKYF"
     gene            complement(6891..7457)
                     /locus_tag="KOU88_003798"
     CDS             complement(6891..7457)
                     /locus_tag="KOU88_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HBK3213614.1"
                     /translation="MRKLEEILEYNKSFVENKEYEQYVTSKHPNKKIVVLSCMDTRLT
                     ELLPKAMNLKNGDVKLIKNAGATIMHPFGSIMRSVLVAIYEFDVDEVMVVGHHGCGMC
                     NVDTDKLLGKILDRGISNDVILTLRSAGIDTKQWLHGFDSAEESVKDSIDLIKGHPLI
                     PDGIIVHGLIISPETGKLDVVVNGYEDK"
BASE COUNT         2455 a         1390 c          786 g         3020 t
ORIGIN      
        1 catacttttt atacttatta tattctatat tgctacattc tacatctaaa atagctccat
       61 cttctctgta ttctgtattt ataatgctcg tattttcgtt aaaataagaa actacatgac
      121 ctttatcata tggaattaag aacttacatc ttacataatc tttaaatatg ctatcacaaa
      181 tacattttat cattttatct atatttatat cttttttaac tgaaacaaat ataccttctt
      241 tatcgatact atctaaaatt ctatccaata cttctacatc tattaaatca attttattat
      301 acacatgtat cataggtata ccatctgcac ctatttgttt taaagtatct tctgtcactt
      361 taatatgact tttatagctt ggatttgaaa tatcaataac atgtaacagt acgtctgcct
      421 cacatgcttc ttctaatgtt gacctaaatg cttttactaa gtcatgtggt agattactta
      481 caaaaccaac agtatcagat aataaaaatt ctttgttatt tgcaagaact atatttctga
      541 cagaagtttc aagtgtagca aataacatgt ttttctcaaa cactttcttt tcttcagagt
      601 ttttaaatat atctactagt ttattcatta ttgaagattt accagcattt gtatacccga
      661 ctagagctac atttggaaga tttgattttc ttctcatact tctttgagtt tctctttgga
      721 attttaaatc atccaactcc ctatttaaag atgttatctt ttcttctatt cttctacggt
      781 caagttctaa ttttttctca ccagaacctc tatttttagt accaactcca ccactttgac
      841 gtcctaaatt ttcatttgaa cctataagtc ttggtaacat atattttaaa cttgctactt
      901 ctacttgaag tttagcttct ctagtttttg ccctttgtgc aaatatatca agtatcaatg
      961 ccgttctatc tataatttca caattaagct tttcttcaag attttttagt tgtgatgtag
     1021 aaagttcatt gtaaaatata actatctcta tattttcttt ctttattaag tttaatattt
     1081 cctcaacttt acctgtccca atgtaaaatg ctctattaac ctgctttgca ttttgagtta
     1141 tactccctac aacatcaata tcacatgctg aacataagtt ttcaagttca atcattagtt
     1201 cattaaagtc ctcagattta ttatttatgt ttaatcctac tgttattcct tttttcgcca
     1261 tatccatatt ctccttatct gctatttttt atttaatcta tagcacgaga ttatggctct
     1321 ataattaaat tcatcaagaa ttttgctttt tatcttatcc ttaaatgaca cttcttattt
     1381 actattataa taaccataat cgtgcattat tttctcaatc ttatataaaa aatcactttc
     1441 ttacacctcc tcccaaatat attatgcagt tttttcaata aaaaaactcc ttacaaatct
     1501 aagtaataca aaacaagcta cttatatcat aagaaggatt aaaattctaa atatatatta
     1561 aaaatacatt agtttaatta acttatatgt aattatcatt ttatatttaa ccctattctt
     1621 aaatttaagt agttatttgc atgattaata aaagtaataa aaacatatac ttcaatataa
     1681 tcatcaacta ttaaaattaa attctattta taataaaatt taaagaataa aattaaatat
     1741 acattttgat aatcacctcc aacattttcc ttactacata ttataataaa ataaacactt
     1801 tgtaaagaca taaaattatg tggctatctc aaaatataga gaatcctctt tttcattgtt
     1861 aaaatgataa aaatacactt tatttcatac acaaaagagt gccttatgaa ttaaaaagtt
     1921 cattttaagg caccctcatt tattttatct tattaattac atgtctatgc taagatagtt
     1981 ttttgttaca ttgcttcatc ttcttcaaat tgagaattgt aaagattggc atagaatccg
     2041 cctttcttta gaagttcctc gtgatttcct tgttcaacta tatctccttc attcattaca
     2101 agaatcatat cagcatcacg tatagttgat aatctgtggg ctataacaaa acttgttcta
     2161 ccttccataa gattatccat agctttttga atcaatactt ctgttctagt atcgacagaa
     2221 cttgtagctt catctaatat taaaatttta ggatcagcta aaatagcacg agctatagtc
     2281 aataattgtt tttgaccttg agaaacatta cttgcttctt catttaattt catcttatat
     2341 ccatctggta atgtcttaat aaatctatga acatgtgcag atttagcagc ctctataact
     2401 tcttcatctg tagcattcaa cttaccatat cttatatttt ccataattga accactaaat
     2461 aaccatgtat cttgaagaac cataccaaac atttctctaa gctcactacg attaaaatct
     2521 ttaatattat gaccatcaat cagtattgaa ccgctattaa catcataaaa tctcattaac
     2581 agtttaacta ttgtagtttt acctgctcct gtaggtccaa caatagcaac tttttgacca
     2641 ggtttaacat ttactgagaa atcatttatt atagtcttgt ttgggttata tccaaagttg
     2701 acattttcaa aatcaatttt accttctaaa ccatctattg aaactgcatt ttcaacaatt
     2761 tggacttctt cttcctcttc taaaaactca aatactcttt cagaagctgc tgctgttgat
     2821 tgcaataaat tggcaacctg tgcaatctga gtcattggct gtgtaaagtt tcttacatat
     2881 tgtataaatg actgtatgtc accaacctca attgttttct taattgcaag ccaacctcct
     2941 aagattgata ccattacata tcccaagttt ccaataaaca tcataagtgg ttgcattata
     3001 cctgataaaa attgagattt ccacgctgaa ttatacaggc tatcatttag tttatcaaac
     3061 tcttcaatta cttcatcctc acgattaaat gcttttacta ttgtttggcc actgtaagtt
     3121 tcctcaactt gaccatttac atttcctaaa tattcttgtt gatatctaaa gtatttttgt
     3181 gatttcttta ttattcttga aattacaaac attgatattg gtaatattaa aactgccact
     3241 aatgtcataa ttccacttat agataacatc attatcaaaa cacctatcat agttgttact
     3301 gatgttataa gctgtgtcat actttgattt aaactttgat ttaaagtatc tatatcattc
     3361 gtaattctcg ataatatttc accatgcgtc ttagtatcaa aatacttcat tggcaatcta
     3421 tccaattttg ctgaaatctc ttttcttaaa ttataggata ctttttgaga aattccactc
     3481 attataaatc cttgtataaa agagaacagt gcacttatca aataaaggaa aagtaaaaag
     3541 gttaagattt ttccaattgc attaaaatct atacctacgt ttcctccaga aactttactc
     3601 actagccctt caaatatctt tgtagttgcc tttcctaaaa tttttggacc tactatagaa
     3661 aacgacgcac taccaatagc aaatacaatt actagaatta ttgatatttt aaatttagat
     3721 aaatatgcaa ttagttttcg catagtccct ttaaagtcat ttgctttttg tcctgctccc
     3781 atagattttc ccataggacc tcttcccatt ctactcatta gctagctcct cctttgaaag
     3841 ttgtgataaa gctatttgct cataaacttc gcaatttttt agaagctctt tatgtgttcc
     3901 tattccaact atttcgccct catttaaaac aattatctgt tctgcattta agatagtact
     3961 aattctttgt gcaactatta gaactgtact ttcagcagtt tttgatttta aagccttacg
     4021 aagagctgca tcagttttta agtcaagtgc tgaaaaacta tcatcaaata tataaacttc
     4081 tggatttttt gctattgctc ttgcaataga aagtctttgt ttttgacctc cagatacatt
     4141 tgttccacct tgagaaattt cagttttaaa agcttccggt ttagaatcta taaattctgt
     4201 agcttgagct atttcagctg ctgttctcat ttcttcatct gttgcgtctt ttctaccata
     4261 ttttaagttg gattctatag taccagaaaa caatactccc ttttgaggta catatccaat
     4321 tttttccctt aaatcatgtt gagaaacatt ttttatatta actccaccaa gtaatatttc
     4381 tccttcagta acatcaaaga aacgaggaat taaatttata agagttgact taccactacc
     4441 agtacttcct ataaaggcag ttgtttctcc tggctttgct gtaaaagata tatttgttaa
     4501 tataggttct tctgcgtctg gatacatgaa cgaaacattt ttaaattcaa caagaccctt
     4561 tttatcttcc ttaaactctt gtgcctctga tttttctggg tcttttatgc ttatatctga
     4621 cactaatact tcatctatac gtgtagctga aacggatgct cttggaagca taatagatac
     4681 cattgatatc attaagaatg acattattat ttgcattgta tattgtataa atgccatcat
     4741 atctccaact tgcattgctc cagaatcaac actgtatgca cctctccaaa ctataagaac
     4801 tgtgataagg ttcattataa gcatcatagc aggcatcata catgtcataa ctctatttac
     4861 aaaaagattt gttttagtta aatttttatt tgctttatca aatctttctt cttcatgttt
     4921 ttcagtacta aaagctctga taactggaat accagtaatt atttcacggc ttactaagtt
     4981 taacttatca acaagctttt gaaccagttt aaacttaggc ataaccactg agaataacac
     5041 tacaattaat gataagatag caactactgc tactgctata atccaggcca ttgaagtatt
     5101 tgtgtttaaa acctttatca ctccacctat agccattata ggtgcataga atactattct
     5161 aagcaacata accatcaaca tttgtatctg ttgaatatca tttgtactac gagtaattaa
     5221 tgaagctgta gaaaattcat tcatttcagt atttgaaaat gacataactt ttctaaatac
     5281 tccacttctt aaatttctac ctacacttgc ggctactctt gctgctaaaa atcctactgt
     5341 tattgtagct accatactaa tcattgctat accaagcatt ttagcaccag taaataatat
     5401 ataattattt tgagtttttt ctgtatcaat acctattttc tcatattctg accttacata
     5461 tgaaacagag ctttgtgtta tcatactctc tggcatactt tcaaagcctt tgctcatctc
     5521 tttagtcaat gtatctaact gttcctttgg cattgctgat aacaatttaa atatatcaac
     5581 atctccactt tgagtagctt gtggtggaag tttgctcatt aactgagctt tcatagcttt
     5641 tacctcttta ctatcgccct caagccctga tactattaaa atagctttac caaaaataac
     5701 atttaaatca tctatagtgt ctttgtcttt agtatttaac tcataaagag attcatcttt
     5761 tagacctgga tacttatctt tatacttaac ataatccttt ttattcagca aagtataatt
     5821 atctagtact ttatccttac tacttttatc cataaataaa gtaattttat ttaattcact
     5881 ctctctaatc acagatggaa cagagttttc tactccacct tgttgtatac ctacatttac
     5941 tatattggat gtgtattctg gtaaagaaag gtcacatacc gcttgaatta ccaatagaca
     6001 gactattatt actattgata atgccgattt ctttaaatat ttaattaatt taaacataca
     6061 tttcttccct tctgtaatat taattagtct aataacatta aattgaaaaa cattatttta
     6121 aactttaaaa atatttttca tcttcatgct tatgacatcc tgcttttaaa ttatctcgta
     6181 cttgcattag aagtcttcta agtactattt tttcttcttc actaaatcct aaaaaaaact
     6241 ctctttccaa ttccttgtta aattcttcaa ctttattaca tatttctaaa cctttgtctg
     6301 tcaaaaaaat cctagatact ctttggtcct tttcatcttg ttttctttcc acaagtccag
     6361 ctttttccat cctctttatc ataactgtag ttgtagatgc ttttactttc cttttatctg
     6421 ctaattcttt ttgactttgc ccatctttca tctttaaaga aaaaagtatt tggggttgac
     6481 catgatataa gcctaattta tcaaaataaa aatgagttct tataaaatat attcgcatta
     6541 attgcaagaa aacatcattt aatttttctt cagaattgct attcatactt gccctcctta
     6601 ttttttatat tacttagtcg gctaagcatt attttactat actgcatgca ttttttcaat
     6661 atatttataa aaaattcata taaatttcat ttattaaata tttttatatc atatagttat
     6721 aattttaata aataatagta agatttttaa ttagtcagct acttatattt tttattgtaa
     6781 agcttaaaat aaaccttttc atatattttc aaataaaaaa gttgtcccaa aataaatttt
     6841 gaaacaacat catattcaac agtatcttga ttatataaca ttatgatact ctacttatct
     6901 tcatatccat ttacaacaac gtctaacttc ccagtttcag gtgatataat tagaccatgt
     6961 acaataatac catctggaat taaaggatgc ccttttatta aatcaatact atcttttaca
     7021 gattcttctg cagaatcgaa tccatgtaac cattgttttg tatcaattcc agcactacga
     7081 agtgtaagta ttacatcatt agatattcct ctatctaaaa ttttaccaag taacttatcc
     7141 gtatcaacat tacacatacc acatccatga tgccctacaa ccataacctc atctacatca
     7201 aattcgtaaa ttgcaactaa aacacttctc ataatacttc caaaaggatg cattatagta
     7261 gctcctgcat tttttattag tttcacatct ccatttttca aattcatagc cttaggcaaa
     7321 agctcagtta atcttgtatc catacaagat aagactacta tttttttatt tggatgtttt
     7381 gatgtcacat attgttcata ttctttgttc tctacaaatg atttattata ttctaatatc
     7441 tcttcaagtt ttctcatatg taatatcacc ctctttaaaa atttttttat tattatatca
     7501 ctattaaagt acaatatata cacatataat ttaatttata tttattaaat tattttataa
     7561 gattattact ctactataaa tcttgtatat aacttgtatt tataagtatt tgtatattta
     7621 ttttttataa tctaaactaa tattatatat t
//
LOCUS       DAFAZV010000092         7642 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFAZV010000092 DAFAZV010000000
VERSION     DAFAZV010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7642
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.095"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            21..1079
                     /locus_tag="KOU88_003799"
     CDS             21..1079
                     /locus_tag="KOU88_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium channel family protein"
                     /protein_id="HBK3213615.1"
                     /translation="MNCKWISKIDERKKCHREADSSGYCIFHKENKSDEEIQLMMDTL
                     HKEEISEFNGFVFENEFNAEEILTYNYKILDFSESIFKQKANFKKYIFKKNIIFNYTE
                     FRDKVLFNGCVFLENCDFNRTIFSKHYINDRIFEKVKFKGPDLVVNKVENFPRMDGII
                     FSMCTKFVLKNVEYGKSEYEHGKINYRIARNQATKIGEYEMIGSYYYKERIYSSKIMK
                     RSNYPTFSDYLVEKFFDQIARYTTGYGEKPWNILLVIIAIISVFALLYLFVGIESSNS
                     TLVALDINNIGDYSLSEIFKMYMDLWYFSMATFSTVGYGDMVATSLIGKALAGIEVFF
                     GVTIGAIWASVIIKRMIR"
     gene            1183..2367
                     /locus_tag="KOU88_003800"
     CDS             1183..2367
                     /locus_tag="KOU88_003800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBK3213616.1"
                     /translation="MKNALKKIISLAMILVFIIPNYSYADDKSVDKYSKTSILIDQET
                     GRVLYSKEPDMKVPLASLSKMMTFLLAIEAIENKEVKETDKVKIDKSIASVKGSSYKL
                     KDGEEVPLIELMRGLMIVSGNDAAIAIAKHICKTKEAFVDRMNKKAKEIGMSNTHFLN
                     PNGLPIYDLSNPKKPAKENISTAKDIAILGKYMFDHYEKQVTAITDMETYTNSDRSFE
                     KSNTNALLRIIPEVDGIKTGYTGNAGYCLSFSMVVNKNDKNEKKRRVIGVVLGTNHKN
                     KRTSASLALLKYGKENFNMKKVIDKDSFIGKKYIKGMKELEVTLKAKDELYTILKDDE
                     SIKSEVKIKNIEYPVKKGDTMGIIKYYTNSGDLLGSVDIVSNNSIDNVSLKTKLKMKF
                     AN"
     gene            2574..3287
                     /gene="rpsB"
                     /locus_tag="KOU88_003801"
     CDS             2574..3287
                     /gene="rpsB"
                     /locus_tag="KOU88_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBK3213617.1"
                     /translation="MSVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIYIIDLQ
                     KTVKKVEEAYKFTKEVAETGKPILFVGTKKQAQDAIKDEAERCGMYFVNERWLGGMLT
                     NHKTIKTRINKLRELEKMEEEGVFNVLPKKEVIKLRAEKEKLEKYLGGIKDMPELPGA
                     MFVVDPRKENIAIQEAHRLGIPVVGIVDTNCDPEQLDFAIPGNDDAIRAVKLITGAMA
                     TAVIEGRQGAEEEVAEDQE"
     gene            3366..4277
                     /locus_tag="KOU88_003802"
     CDS             3366..4277
                     /locus_tag="KOU88_003802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBK3213618.1"
                     /translation="MANITAQMVKELRESTGAGMMDCKKALQEAEGNMEKAVDLLREK
                     GLSKAAKKAGRVAAEGLVAIEMNDDNTVASMVEVNSETDFVAKNEDFKVFVKDAACMA
                     LATDKEDIASLLGETHKEGITLQEVLNNRVAKIGEKLDFRRFAKVVTNGQVAGYIHGG
                     GKIGVLVEMETEARDAKVLELGKDVAMQVAAMNPKYVSRDEVDAEYIAHETEVLTQQA
                     LNEGKPANIVEKMVKGRLEKELKEVCLLEQTFVKNPDITVKQLVADVAKAVGSDIKVV
                     KVVRFEVGEGIQKREENFAEEVAKQLK"
     gene            4362..5066
                     /locus_tag="KOU88_003803"
     CDS             4362..5066
                     /locus_tag="KOU88_003803"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBK3213619.1"
                     /translation="MDKPMYKRVLLKLSGEALAGERGFGINNDVVNDIAIAIKKIQEI
                     GVEVAVVVGGGNFWRGRTSEGMDRTTADYIGMLATVMNAMALQDALENIDVATRVQTA
                     IDMRQIAEPYIRRRAVRHLEKERVVIFGAGTGNPYFTTDTTAALRAAEMEAEVILLAK
                     NVDAVYDKDPKVHADAKKFTELSYMEVIQKELKVMDSTATSLCMDNKIPIKVFELTTE
                     NIIRAVKGENIGTTVK"
     gene            5092..5649
                     /gene="frr"
                     /locus_tag="KOU88_003804"
     CDS             5092..5649
                     /gene="frr"
                     /locus_tag="KOU88_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBK3213620.1"
                     /translation="MKLEIHKQLEEKMNGTIDALKFEFGTIRAGRANAQMLDKIRVDY
                     YGTPTPINQIGAISVPEPRILMISPWDKSAMHEIEKAIANSDLGLNPSNDGEVIRLSV
                     PALTEERRKELAKKASKAAEEFKVRIRNERRDANEKIKKMEKGGELTEDELKKAQDEV
                     QKMTDKFIKEIDTLLSKKEKDIMEV"
     gene            5652..5855
                     /locus_tag="KOU88_003805"
     CDS             5652..5855
                     /locus_tag="KOU88_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213621.1"
                     /translation="MKKYYNLLGLHVDEVKQYFDEQNINYTVKSIEGKKDKEKLVVPR
                     VIKISEIGDSVELIITYFSDSLV"
     gene            5884..6618
                     /locus_tag="KOU88_003806"
     CDS             5884..6618
                     /locus_tag="KOU88_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBK3213622.1"
                     /translation="MNNNIIYDIDLNNIPTHIAIIMDGNGRWAKARFLPRTAGHKAGV
                     ETIRDIVKECSKLGVKHLTLYAFSTENWKRPKLEVDTLMNLLSTYLRNEIAELHQNNV
                     KVTAIGDISALPKTCIRELNSAKELTKNNTGVNLNLALNYGSRADIKNALIDIVKNCE
                     SGKIDINNIDEDIIKNYLSTKSIPDPDLVIRTSGEQRLSNFLLWEVAYSEFYFTDIHW
                     PDFKKEELQKAIYVYQRRDRRFGGLK"
     gene            6631..7410
                     /locus_tag="KOU88_003807"
     CDS             6631..7410
                     /locus_tag="KOU88_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBK3213623.1"
                     /translation="MLTRIIASLALVPLFLFVVYGGIPLYIAETAIVYIALHEFYKAF
                     KIKDVHPIFIIGYLFSIYLAVKNIFNLPLEYTYAVIFILFLASIIYMLMGKNNVIDVS
                     ITFLGVFYIGVFLDFIIITINGFEKGSIYVWLIFVISFMTDIFAYFSGYLLGKHKLIP
                     KVSPKKTIEGAIGGIIGSTLCCILFGYLFGIDLLQLAIIGSIGSVIAQLGDLFASSIK
                     RYVGIKDYGKIIPGHGGILDRFDSVILVAPFVYSAIKFFIR"
BASE COUNT         3145 a          786 c         1453 g         2258 t
ORIGIN      
        1 gtactggagg atatatattt atgaattgta aatggatatc taaaatagat gagagaaaaa
       61 aatgtcatag agaagcagat tcttctggat attgtatctt tcataaagaa aataagtctg
      121 atgaagagat acagttgatg atggatactc ttcataaaga agagataagt gaatttaatg
      181 gatttgtttt tgaaaatgaa tttaatgcgg aagaaatatt aacttacaat tataaaatac
      241 tggatttttc tgaatccata tttaaacaaa aagcaaattt taaaaaatat atttttaaaa
      301 agaatattat ttttaactat acagaattta gagataaagt tttatttaat ggttgtgtat
      361 tcttagaaaa ctgtgatttt aatagaacca tatttagtaa acactatata aatgaccgta
      421 tatttgaaaa agtgaaattt aaaggacctg atttggtagt taataaagta gaaaattttc
      481 cacgaatgga tggaataatt tttagcatgt gtacaaaatt tgtgttaaag aatgttgaat
      541 atggaaaaag tgagtatgag catggcaaga taaattatag aatagctaga aatcaagcaa
      601 caaaaattgg agaatatgag atgataggat cttactatta taaggaaaga atttatagta
      661 gtaaaataat gaaacgttct aattatccta ctttcagtga ttatttagtt gaaaaatttt
      721 ttgaccaaat agcacgttac acaacaggtt atggagaaaa gccatggaat atattattag
      781 ttattatagc aataataagt gtttttgctt tattatactt atttgtaggc atagaaagtt
      841 caaatagcac acttgtagct ttagatataa acaatatagg tgattactca ctaagtgaga
      901 ttttcaaaat gtatatggat ttatggtatt ttagcatggc tacatttagt acagtaggat
      961 atggagatat ggttgctaca agtttgattg ggaaagcatt ggcaggtata gaagtatttt
     1021 ttggagttac aataggagca atttgggcat ctgtgattat taaaagaatg ataaggtaat
     1081 atttgtgtaa atatggatag gtattaatta ctagatataa attggactaa atagggaaaa
     1141 tttaaatata aatatactta ataatccaag aaggtgaaaa atttgaaaaa tgcactaaaa
     1201 aaaattatat cattagccat gattctagtt tttataatac caaattattc atatgcagat
     1261 gataaatctg tagacaagta ttcaaaaaca tctatactta tagaccaaga aacaggtaga
     1321 gttttatata gtaaagaacc tgatatgaag gtaccattag ctagtttaag taagatgatg
     1381 acttttttac ttgcaataga agctattgaa aataaagaag taaaagaaac tgataaagta
     1441 aaaatagaca aatctattgc atcagtaaaa gggtcaagtt ataaacttaa agatggtgaa
     1501 gaagtgccac ttatagagct tatgagaggt cttatgattg tatcaggaaa tgatgcggca
     1561 attgctatag caaaacatat ttgtaaaacg aaagaagcat ttgtagatag aatgaataaa
     1621 aaagcaaaag aaataggaat gagtaataca cattttctaa atccaaatgg tcttccaata
     1681 tacgatttaa gcaaccccaa aaaaccagca aaagaaaata tctctactgc aaaagatata
     1741 gctattcttg gaaaatacat gtttgaccat tatgaaaaac aagtaacagc tataactgat
     1801 atggagacat atacaaattc agatagaagt tttgaaaaaa gcaatacaaa tgcattatta
     1861 agaattatac cagaagtaga tggtataaaa actggatata ctggcaatgc tggatattgc
     1921 ttatcatttt ctatggttgt aaataaaaat gataaaaatg agaaaaaacg tagagtaata
     1981 ggggttgtat taggtactaa ccataaaaat aaaagaacct ctgcttcatt agctctactg
     2041 aaatatggaa aagaaaattt caatatgaaa aaagtaattg ataaagatag ctttattggt
     2101 aagaaatata taaaaggaat gaaagagtta gaggttacat taaaagcaaa agatgaactt
     2161 tatacaatat taaaagatga tgaaagtata aaatcagaag ttaagattaa aaatatagag
     2221 taccctgtta aaaaaggtga tactatgggt attataaaat attatactaa ttcaggtgac
     2281 ttacttggaa gtgtagatat agtaagtaat aatagtatag ataacgtatc attaaaaaca
     2341 aaattaaaaa tgaaatttgc aaattaaatt caaaaaatgg tataaaatac acaaaaaaat
     2401 ataaaaatag aaaatatgga aaaaatattg ttatttcttc acctctgtga tatactacta
     2461 gaggtgaaaa aataaaataa atcacacaca gcattgggat ccttaaaagg tgcctattac
     2521 atggtttttt agggagaaga tcaagctgga ggtataaaac caggaggtaa gatatgtcag
     2581 taatatcaat gaaacaatta ttagaagcag gtgttcactt tggtcaccaa acaagaagat
     2641 ggaaccctaa aatggctaag tatatattca cagagagaaa tggaatatat ataatcgact
     2701 tacaaaaaac agttaaaaaa gttgaagaag cttacaagtt cactaaagaa gtagctgaaa
     2761 caggaaagcc aatcttattc gtaggaacta aaaaacaagc tcaagatgcg ataaaagatg
     2821 aagctgaaag atgtggaatg tactttgtta atgaaagatg gttaggtgga atgttaacaa
     2881 accacaaaac tataaaaaca agaataaata aattaagaga attagaaaaa atggaagaag
     2941 aaggcgtatt taatgttctt cctaaaaaag aagttataaa attaagagct gaaaaagaaa
     3001 aactagaaaa atacttaggt ggaataaaag acatgcctga attaccaggt gcaatgttcg
     3061 tagttgaccc aagaaaagaa aacatagcta ttcaagaagc tcatagatta ggtataccag
     3121 tagttggtat agttgatact aactgtgacc cagaacaatt agactttgct ataccaggaa
     3181 atgatgacgc tataagagcc gtaaaattaa taactggtgc tatggcaaca gctgtaattg
     3241 aaggtagaca aggtgctgag gaagaagtag ctgaagacca agaataataa tttgacaatt
     3301 aaatggtaag ggtcgccctt accatttata atatggaata gaataagtag gaggaaactt
     3361 aaaaaatggc taatataact gctcaaatgg taaaagagtt aagagaaagt acaggcgcag
     3421 gaatgatgga ctgcaagaaa gctttacaag aagctgaagg aaacatggaa aaagcagtag
     3481 atttattaag agaaaaagga ttatcaaaag ctgctaaaaa agctggtaga gttgctgctg
     3541 aaggtctagt tgcaatagaa atgaatgatg ataatacagt tgcttctatg gtagaagtta
     3601 actcagagac agatttcgtt gctaaaaacg aagacttcaa agtgttcgtt aaagatgctg
     3661 cttgtatggc attagctact gataaagaag atatagcttc tttattaggt gaaactcata
     3721 aagagggaat aactttacaa gaagttttaa ataatagagt tgcaaaaata ggtgagaaat
     3781 tagactttag aagatttgct aaagttgtaa ctaatggaca agttgctgga tacattcacg
     3841 gtggtggaaa aataggtgtt cttgttgaaa tggaaacaga agctagagat gctaaagttt
     3901 tagaattagg taaagatgta gctatgcaag ttgctgctat gaatcctaag tatgtttcaa
     3961 gagatgaagt agatgctgaa tacatagcac atgaaacaga agtattaact caacaagctt
     4021 taaatgaagg aaaaccagct aatatagttg aaaaaatggt taaaggaaga ttagaaaaag
     4081 aattaaaaga ggtttgttta ttagagcaaa ctttcgttaa aaatccagat ataactgtta
     4141 aacaattagt tgctgatgtt gctaaggcag taggttctga tataaaagtt gttaaagttg
     4201 tgagattcga agttggtgaa ggtatacaaa agagagaaga aaactttgca gaagaagttg
     4261 ctaagcaact taagtaataa ccaaagagag aacacgcagg tgttctcttt tttaaaaaat
     4321 agaaaaaatt ggatatgaag gattgaaata ggaggtttct gatggataaa ccaatgtaca
     4381 aaagggtatt gttaaaatta agtggagaag cattagcagg agaaagaggt tttggtataa
     4441 ataatgatgt agttaatgat attgctattg ctataaaaaa aatacaagaa ataggtgttg
     4501 aagtagctgt agtagtaggt ggaggaaact tctggagagg cagaaccagt gaaggaatgg
     4561 acagaactac tgctgactat ataggaatgt tagctacagt tatgaatgca atggcgctac
     4621 aggatgcact agaaaatata gatgttgcta caagagttca aactgctata gacatgagac
     4681 aaattgcaga accatatata agaagaagag cagttagaca cttagaaaag gaaagagttg
     4741 ttatatttgg tgcaggaaca ggaaaccctt actttacaac agatacaact gctgctttac
     4801 gtgctgctga gatggaagca gaagttatat tgttagctaa aaatgttgat gcagtatatg
     4861 acaaggatcc aaaagtacat gcagatgcta agaaatttac agaattaagt tacatggaag
     4921 ttatacagaa agaattaaaa gtaatggatt ctacagctac atctttatgt atggataata
     4981 aaattccaat aaaggtattt gagcttacaa cagagaatat aataagagca gtaaaaggcg
     5041 aaaatatagg aactactgta aaataatgaa gaatgaagga ggagtaaaat tatgaaactg
     5101 gaaatacata agcaattaga agagaaaatg aatgggacaa ttgatgcttt aaagtttgaa
     5161 tttggaacta taagagcagg aagagctaat gcacaaatgc tagacaaaat aagagttgat
     5221 tattatggaa ctccaactcc aataaatcaa ataggtgcta tatctgtacc agaaccaaga
     5281 atattaatga tatctccttg ggataaatct gctatgcatg aaatagaaaa agcgatagct
     5341 aactcagact taggattaaa tccatcaaat gatggtgagg ttataagact ttctgtacct
     5401 gctttaacag aagaaagaag aaaagaatta gctaaaaaag ctagtaaagc tgcagaagaa
     5461 tttaaagtta gaataagaaa tgaaagaaga gacgccaatg agaaaattaa aaagatggaa
     5521 aaaggcggag aattaactga agatgaatta aaaaaagcac aagatgaagt tcaaaaaatg
     5581 actgataaat ttataaaaga aatagataca ttattatcta aaaaagaaaa ggacataatg
     5641 gaggtataat attgaaaaaa tattataacc ttttaggtct tcatgtagat gaggtaaaac
     5701 aatattttga tgagcaaaat ataaattata ccgtaaaatc tattgaaggt aaaaaggata
     5761 aagaaaaact tgtagttcct agagttataa aaatatctga gataggtgat agtgtagaac
     5821 tgataatcac atacttttct gactccttag tttaaggagt cagaacaata ttggaggcaa
     5881 aatatgaata acaacattat atatgatata gacttaaata acatacctac tcatattgct
     5941 attataatgg atggaaatgg aagatgggca aaagctagat ttcttccaag aactgcagga
     6001 cataaggctg gagtagaaac tataagagat atagtaaaag aatgctcaaa attaggtgtt
     6061 aagcacttaa cattatatgc attttcaaca gaaaactgga aaagaccgaa acttgaagtt
     6121 gacacactta tgaacttatt atctacatac ttaagaaatg aaatagctga acttcaccaa
     6181 aacaatgtaa aagtaactgc tataggagat ataagtgctt taccaaaaac ttgtataaga
     6241 gaattaaact cagctaagga actgacaaaa aacaatacag gagttaactt aaatttagca
     6301 ttaaactacg gaagtagagc agatataaaa aatgctctta tagatatagt aaaaaattgt
     6361 gaaagtggta aaatagatat aaacaatatt gatgaagata ttataaaaaa ctatttaagc
     6421 acaaagtcta taccagatcc agacttggta ataagaacaa gtggtgaaca aagattgagt
     6481 aactttttac tttgggaagt tgcttattct gagttttact ttactgatat acattggcct
     6541 gattttaaaa aagaagaact acagaaggct atatacgtat atcaaagaag ggatagaaga
     6601 tttggaggac ttaagtaagg agattatttt atgcttacaa gaattattgc ttcactagct
     6661 ctggttccat tatttctatt tgttgtatat ggaggtattc ctctatatat agctgagaca
     6721 gcaatagttt atattgcatt gcatgagttt tataaggcat ttaaaataaa agatgtacat
     6781 ccaatattca ttataggata tttattttct atttatttag ctgtaaaaaa tatttttaat
     6841 ttaccattag aatatactta tgcagtaatt tttattttat ttttagcaag tataatttat
     6901 atgttgatgg gcaaaaacaa tgttatagat gtttcgatta cgtttttagg agttttttat
     6961 ataggagtat ttttagattt tataattata actataaatg gatttgaaaa aggtagtata
     7021 tatgtatggc ttatatttgt gatatctttt atgacagata tatttgcata ttttagtggt
     7081 tatttacttg gaaaacataa gctaattcct aaagttagtc ctaaaaagac tatagaagga
     7141 gctattggag gaataatagg aagtacactt tgttgtattt tatttggata tttatttggc
     7201 attgatttgc ttcaattagc gataatagga agtataggaa gtgtaatagc tcaattagga
     7261 gatttatttg catcttctat aaagagatat gtagggataa aggattatgg aaagataata
     7321 cctggtcatg ggggtatatt agatagattt gatagtgtta tattagttgc accttttgta
     7381 tatagtgcga ttaaattttt tattagataa agattggttg gatttaaaag agcaatctat
     7441 aattgctagt aatgaaaata gctatgtaac ttttaaatgc agagatattc tgcagttatt
     7501 agttacatgg ctattttcat tgttcaaaaa tttagaagac cttggggaat tgtataagaa
     7561 taggtattac tttataatag tatactatat ttgtagtgag tatatttttt atactataac
     7621 tatcattaaa aaatattttt tt
//
LOCUS       DAFAZV010000093         7407 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.096, whole genome shotgun sequence.
ACCESSION   DAFAZV010000093 DAFAZV010000000
VERSION     DAFAZV010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7407)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7407)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7407
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.096"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..732
                     /locus_tag="KOU88_003808"
     CDS             <1..732
                     /locus_tag="KOU88_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBK3213624.1"
                     /translation="LNATLESCDLAICLYSQKDEKKVAILKLDYNKSYTHSIEFEDDK
                     FNIQMSKNEINIQETKTIKIGAIIGLSGVNDEYHLRVLDKDAEKEEANSKFVTEFLNA
                     TKVKDDKYKTKMFKSTAENWITNALGNDIKQAEDVRSILNYTLKEKHEIDINNFVDKT
                     IKDDKLKDSFKEHMEEKGLDKGFSIDKKWVEKKLKKRNIKTDNGFDIKGNLTDFEDPM
                     KYTVRQNQNGSIDIIIKNVKFYEEK"
     gene            741..914
                     /locus_tag="KOU88_003809"
     CDS             741..914
                     /locus_tag="KOU88_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213625.1"
                     /translation="MTNKEMCKSKNLDEREIYKEFGKEICASCISDRVDCESKDCDTT
                     YENWLEKETKNYL"
     gene            932..1255
                     /locus_tag="KOU88_003810"
     CDS             932..1255
                     /locus_tag="KOU88_003810"
                     /inference="COORDINATES: protein motif:HMM:NF020435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBK3213626.1"
                     /translation="MLLVENKNDRSILAKESLEKLGAKNVKIYNMDTGSNVIYSVENG
                     KEHLTISNEKRFPNWNEIKYVRYKLMKPNKTIVQILPPKEEYINLHENCFHLWEIEDN
                     AVPTK"
     gene            1342..1539
                     /locus_tag="KOU88_003811"
     CDS             1342..1539
                     /locus_tag="KOU88_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213627.1"
                     /translation="MNNKVEINNIQQLNDALNKYDIPFGILSDVDRRICDWMATGGNE
                     DDAYIKQQYRYVENFINRFCD"
     gene            1570..1755
                     /locus_tag="KOU88_003812"
     CDS             1570..1755
                     /locus_tag="KOU88_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213628.1"
                     /translation="MVITEFKVTWQTTSEWLKGGVYSNIFNNLEEARAFKKNQENIKE
                     NYNVKLLSRAIVEIEID"
     gene            1893..2696
                     /locus_tag="KOU88_003813"
     CDS             1893..2696
                     /locus_tag="KOU88_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HBK3213629.1"
                     /translation="MNKVLNWPGAKWSMSKNIVGILPKHNIYLEPYFGSGAVFFNKKA
                     CNTEILNDADKQIVNLFKCIRDNPNELMNAIYFTPYARDEYMNCNILETDNDIEKARK
                     FIIRTNMARGGIQNYKTGWKHTGPKESKKCFQKVVGKWNKLPKIILDTAIRLKDAEIE
                     NRDAVELIKKYNKTDCLIYADPPYLLKTRSQKMYNVEMETEEEHEKLLKTLLKFSGYV
                     ILSGYDSDLYNEMLNGWNKMEFKACAEQGKRKEMLWTNFETTKQLSLFK"
     gene            2709..3116
                     /locus_tag="KOU88_003814"
     CDS             2709..3116
                     /locus_tag="KOU88_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBK3213630.1"
                     /translation="MRINFTIDGEPVGKERPRFNLATKRTYTPNKTKDYEELIKWLYQ
                     SKVKHYFEGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDII"
     gene            3131..3856
                     /locus_tag="KOU88_003815"
     CDS             3131..3856
                     /locus_tag="KOU88_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor Ant"
                     /protein_id="HBK3213631.1"
                     /translation="MNEIMTNENLRVVADDLVTVYETDTGEKIVFARELHNNLEVKRQ
                     FIDWIEDRIKQYGFKENEDYSVFHKNMKNSTGGRPSKEYVLKLDVAKELAMVQNNNKG
                     REIRRYFIRLEKLLNRTLSNSQLSQINTIVNESLLKMEVKHNIQMEQLKKECSEYYRP
                     TSKTKYDISSYIKERLGISKVNEEFELVKKRTLLVLGADKWEDIPKDVLLNSLNLIDE
                     SIRIIKSERKTNQISFFEKDNFC"
     gene            3968..4450
                     /locus_tag="KOU88_003816"
     CDS             3968..4450
                     /locus_tag="KOU88_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213632.1"
                     /translation="MNKKTLFQEVEGRLYNYKKLESQIRIKDIYIKKLESEFCGCKAQ
                     SYEEKTGPTYNISSSVENEVIKREEDLNRLKEDKKTLEIEKETIECALTSLNSFETEF
                     FNEMYMNNEKINMDYMSNAMHIDRSHCFRIRKRIVCKIMDMLYPKIKEFELPIFSWKA
                     "
     gene            4892..5089
                     /locus_tag="KOU88_003817"
     CDS             4892..5089
                     /locus_tag="KOU88_003817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213633.1"
                     /translation="MDDLREKIIKELNEFNIDADDEFLDYGVEYVESFTGKSAISEDL
                     LIRGVVLMANYIVNMENKDLD"
     gene            5219..5905
                     /locus_tag="KOU88_003818"
     CDS             5219..5905
                     /locus_tag="KOU88_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213634.1"
                     /translation="MNEKADLAHEDYLKGLKYKEIAEKHNVSLSTVKSWATRYWKQKG
                     CNQSKKVATKKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELMQEISIKDKFD
                     ILWEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASF
                     LNAQSRAMSELRSLIKQYDEMIHKDWNLATEEQRARVEVLKSKINNQESKEDKLDRYF
                     DKLESVIKND"
     gene            5898..7127
                     /locus_tag="KOU88_003819"
     CDS             5898..7127
                     /locus_tag="KOU88_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBK3213635.1"
                     /translation="MIDELYHSKQLEVLNFALNNDYFMLINYGAKRTGKTIIDNDLFL
                     LELRRVRKIANELDIKLPQYILAGADLGALQRNVLSELTNKYDIEFKFDKHNRFVLFG
                     VQVCCFGHSKTNDLGRIRGMTSFGAYINEGTVANEEVFNEIKSRCSGEGARILVDTNP
                     DQPEHWLKTNFVDKTDGKVIQSFHYRLDDNIFLSERYRENIKKSTPSGVFYDRDINGL
                     WVSADGLVYQDFNKDIHYISKDKLNDINFVRYFAGVDWGYEHFGAIVVIGEDDRGNLY
                     LLEEHSAQHKEIDYWIDKAKNIKEKYGNIKFYCDSARPEHLAAFKRNGIKAFNADKAV
                     LSGVEAVAKRIKTNTLFVVYDNVNLFRKEIFMYAWNKNTGEPIKKWDDVLDALRYAIY
                     TDSLGTGIKVLTPKGRR"
     gene            7132..>7407
                     /locus_tag="KOU88_003820"
     CDS             7132..>7407
                     /locus_tag="KOU88_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213636.1"
                     /translation="MELDVIKKLIEQTNSKHNNFVKKADEAEKYYKNQNDIIRDRSPN
                     NIGKVNTADNPLRNADNRIPFNWFGFLVNQKISYLFTYPPTFDVGDDG"
BASE COUNT         3121 a          729 c         1400 g         2157 t
ORIGIN      
        1 ttgaatgcta cattagaatc ttgcgactta gcaatttgtt tatactctca aaaagatgaa
       61 aagaaagttg ctatattaaa acttgattac aataagtcat atactcattc aattgagttt
      121 gaagatgata aatttaatat acagatgtct aaaaatgaaa ttaacataca agagactaag
      181 acaattaaaa taggagcaat tatcggtttg agtggagtca atgatgaata tcatttaaga
      241 gtcttagaca aggatgcaga aaaggaagaa gctaattcta agtttgttac agagtttcta
      301 aatgctacta aagtgaaaga tgacaagtac aagactaaga tgtttaaaag tacagccgaa
      361 aattggataa ctaatgctct tggaaatgat ataaaacagg cagaagatgt aagaagtata
      421 ttaaattata ctttgaaaga aaagcatgaa attgatataa ataattttgt tgataaaaca
      481 attaaagatg ataagttaaa agatagcttt aaagaacata tggaagaaaa aggtcttgat
      541 aaaggattta gtatagataa aaaatgggtt gagaaaaagc ttaaaaagag aaatataaaa
      601 actgacaatg gctttgatat aaaaggtaat ctgactgatt ttgaggaccc aatgaaatat
      661 acagtaagac aaaatcaaaa tgggtctata gatataatta ttaagaatgt aaaattttac
      721 gaagaaaagt aggtgagcat atgactaata aagaaatgtg caagtcaaag aatcttgatg
      781 aaagagaaat atataaggaa tttgggaaag agatttgtgc tagttgcata agcgataggg
      841 tagattgtga aagtaaagat tgtgatacaa catatgaaaa ttggctagag aaggaaacaa
      901 aaaattattt ataaaatttg gagggaataa aatgttatta gttgagaata aaaatgatag
      961 gtctattctt gcaaaagaat cacttgaaaa attaggggct aaaaatgtaa aaatatacaa
     1021 catggatact gggagtaatg ttatatattc agtagaaaat ggcaaagaac atttaactat
     1081 atcaaatgaa aaaagatttc ctaattggaa tgaaattaag tatgttagat acaaactcat
     1141 gaaaccaaat aagaccatag tacaaatact accaccaaaa gaagaatata taaatttaca
     1201 tgaaaattgc tttcatcttt gggagataga agataatgca gttccaacta agtaatttat
     1261 aaaaataaag tcaaggtaag tttgtgaatg aaactagaat gttatagact tactttgact
     1321 tataaaaagg atgatttgaa tatgaacaat aaggttgaga taaataatat acaacaatta
     1381 aatgatgctt taaataagta tgatatccca tttggcatat taagtgatgt agatagaaga
     1441 atatgtgact ggatggctac tggtggtaat gaagatgatg cttatattaa acaacaatat
     1501 agatacgtag agaattttat aaatagattt tgcgactagg gagtgagatt atgaaaagga
     1561 gtggtcaata tggttattac agaatttaag gtgacttggc agacgactag cgagtggcta
     1621 aaagggggag tgtacagcaa catttttaat aatttagaag aagcaagagc ttttaaaaaa
     1681 aatcaagaaa atataaaaga aaattataat gtgaagcttt taagtagagc tatagtcgaa
     1741 attgaaatag attaaatatg tgagttaaaa ggaagtgatt ctttgaaaag gataagatgc
     1801 agttggtgtg ggaaattatt ttatattgat gaaaaatcta aggatattta ttgttgtaaa
     1861 gaatgtagaa agaaggctaa gaaggtgaaa aaatgaataa ggttttgaat tggccaggtg
     1921 ctaaatggag catgtcaaaa aacatagtag gtatacttcc aaaacataat atatatttag
     1981 aaccatattt tgggagtgga gcagtatttt ttaataagaa agcatgtaac acagagatat
     2041 tgaatgatgc agataaacaa attgtaaatt tatttaaatg tataagagat aatccaaatg
     2101 aattaatgaa tgctatatat tttactccat atgctagaga tgaatatatg aattgtaata
     2161 tccttgaaac tgataatgat atagaaaaag ctagaaaatt tataataaga acgaatatgg
     2221 caagaggagg aatacaaaat tataaaacag gttggaaaca cacaggtcct aaagaaagta
     2281 aaaaatgctt tcaaaaagtt gtagggaaat ggaataagtt acctaaaatt attttagata
     2341 cagctataag gttaaaagat gcagaaatag aaaatagaga tgcagtagag ttaataaaaa
     2401 aatacaacaa aactgattgt ttaatatatg cagaccctcc ttatttacta aaaacaagaa
     2461 gtcagaaaat gtacaatgta gaaatggaaa cagaagaaga acatgaaaaa ttgctaaaaa
     2521 cacttttaaa gttcagtgga tatgtaattt taagtggata tgattcagat ttgtataatg
     2581 agatgcttaa tggatggaat aagatggaat ttaaggcatg cgcagaacaa ggcaaaagaa
     2641 aagaaatgtt gtggaccaac tttgaaacta ctaaacaact tagtttgttt aaataatagg
     2701 agagagtaat gagaattaat tttacaatag atggagaacc agttggcaaa gaaagaccta
     2761 gatttaattt ggctactaaa aggacctata cacctaataa gactaaggac tatgaggaat
     2821 taataaaatg gctatatcaa tctaaagtta aacattactt tgaaggttat ataaaaatga
     2881 ctttaagatg ctattattct atagctaaaa gtaatagtaa aaaggttaag gagcagaaaa
     2941 gaaataatgt gttaagacct agtaaaaaac ccgatattga caatgttgtt aagattatag
     3001 ctgattcact caatgagata gcttataaag atgatactca gattgttgag gttgtagcta
     3061 gtaaatacta tagtgataag ccaagggttg aggttatatt agaagatatt atttaaggag
     3121 gactataaat atgaatgaga ttatgacaaa tgaaaattta agagttgtag cagatgattt
     3181 agttacagtt tatgaaactg atacaggaga gaaaatagtt tttgcaagag aactacataa
     3241 taatttagaa gttaagagac agtttataga ctggattgaa gatagaatta aacaatatgg
     3301 gtttaaggaa aatgaggatt attcagtttt tcacaaaaat atgaaaaact caactggagg
     3361 gagaccttca aaagaatatg tattgaagct tgatgtagca aaagaacttg ctatggtaca
     3421 aaataataat aaaggaagag aaataagaag atattttata agattagaaa agttactaaa
     3481 tagaacctta tcaaattcac agcttagtca aattaatact attgtgaatg aatcattact
     3541 taaaatggaa gttaaacata atatccaaat ggagcaactt aaaaaagagt gttcagaata
     3601 ttatagacca acctctaaaa ctaaatatga tatatcttct tatataaaag aaagactagg
     3661 tatatcaaaa gttaatgaag aatttgaatt agttaagaaa agaactctat tggtattagg
     3721 tgctgacaaa tgggaggata tcccgaaaga tgtattactt aattcattaa acttaataga
     3781 tgaatcaatc agaattataa aatctgagag aaaaacaaat caaattagtt tctttgaaaa
     3841 agataatttc tgttaataaa aagaaaaaag gagtgctttc acactccact tgtcaaaaat
     3901 ataaaacttt tatatacaaa tattattata acataaaaac ataaaaaatt gatgggagtg
     3961 tggaagtatg aataaaaaga cactatttca agaggttgaa ggtagattat ataactataa
     4021 aaaactagaa agtcaaataa gaataaaaga tatatatatt aaaaaattag aaagtgagtt
     4081 ttgcggatgt aaggctcaaa gttatgaaga aaaaacagga cctacttata atataagttc
     4141 aagtgttgaa aatgaagtta ttaaaagaga agaagattta aatagattga aagaagataa
     4201 gaaaacatta gagattgaaa aagaaactat agaatgtgca ttaacaagtc taaatagctt
     4261 tgaaacagag ttcttcaatg aaatgtatat gaacaatgag aaaatcaaca tggattatat
     4321 gtctaatgct atgcacatag atagaagtca ctgttttagg attagaaaaa ggatagtttg
     4381 taaaattatg gatatgttat atccaaaaat aaaagagttt gaattaccca ttttttcatg
     4441 gaaagcttaa aaatgagact attttgagac tttttggaga ctatcgtgag actttttgtt
     4501 ggcaaaaaca tgagataata atatcgtgga aataaagatt tccctctcaa aacttaataa
     4561 ttgctaggtt agtttaaagg gctaatctag caatatgaac agactaggca gggcgtgagg
     4621 acgctgttag ttcaattcta actatgttca aaatctattg atacactata ttaagtattt
     4681 gaattgagat taaaatctca tacagttttg tatcttaatt cagaaatcta aaaaatcggg
     4741 tggggcttgg taacctcact caccatgcag gtagtggttt aatctaggtt caattcctgg
     4801 aacttgcgac ataatatatg tacctcccca ttataaaaga ctaagcaagg gcaagcttag
     4861 tcttttattt ttaaaaaagg agaataaaaa tatggatgat ttaagagaaa agataataaa
     4921 agaactaaat gaatttaata tagatgcaga tgatgaattt ttagattatg gagttgaata
     4981 tgttgagagt tttacaggga aaagtgctat tagtgaagat ttattgataa ggggagtagt
     5041 gcttatggca aattatatag taaatatgga aaataaagac ttagattaat ttctaggtct
     5101 tttttaatac aaaaatttaa taaattttag atgtcggtaa ctccgacagt agaaaagact
     5161 cagattaatt tctaggtctt tttttattcc caaaacgaca aacaaacgag gtggtggtat
     5221 gaatgaaaag gcagatttag cccatgaaga ttacttaaaa gggcttaagt acaaggaaat
     5281 agctgaaaag cataatgtaa gtttatcgac tgtaaaatca tgggcaacta gatactggaa
     5341 acaaaaaggt tgcaaccaat caaaaaaagt tgcaaccaaa aagagaggtg cacccatagg
     5401 taataaaaat gctactggtc caccaggtaa taaaaatgct gaaaagtttg gtttcttctc
     5461 aaagtatcta cctgaagaaa ctagggaatt gatgcaagaa atatctataa aagataaatt
     5521 cgatattctt tgggaacaga taacaattca atatgcagca ataataagag cacaaaagat
     5581 aatgtatgtt aaagacaaag aagaaatgat taaggaatta aagaaacatg aaagcacaga
     5641 aaatggtgag aagatagagt atgaatttca atttgcatgg gataggcaag catcttttct
     5701 taatgcacag agtagagcta tgagtgaatt aagaagttta attaagcaat atgatgaaat
     5761 gattcataag gattggaatt tggctacaga agaacaaaga gcaagggtag aagtattaaa
     5821 atcaaagata aataatcaag aaagtaaaga agataagctt gatagatatt ttgataagct
     5881 tgaaagtgtg ataaaaaatg attgatgaat tatatcatag taaacaactt gaagttctta
     5941 actttgcttt gaataatgac tacttcatgc taattaatta tggtgctaaa agaacaggaa
     6001 aaacaataat tgacaatgat ttattcttac tggaacttag aagggttaga aagatagcta
     6061 atgagctaga tattaagctt cctcagtaca ttctagcagg agcagattta ggagctttac
     6121 aaagaaatgt actaagtgag cttacaaata agtatgatat tgaatttaag tttgacaaac
     6181 ataatagatt tgtacttttt ggagttcaag tatgttgttt tggacactca aaaacaaatg
     6241 acttaggaag aataagaggt atgacttcgt ttggagcata tataaatgag ggtacagttg
     6301 caaatgaaga agtatttaat gaaatcaaat caagatgcag tggagaaggt gctagaatac
     6361 ttgtagatac taacccagac caaccagagc attggttaaa aactaacttt gtagataaaa
     6421 cagatggtaa agttattcaa tcttttcatt atagactgga tgataatata tttctaagtg
     6481 aaagatacag agaaaatatt aaaaaatcta ctccaagtgg cgttttttat gacagagata
     6541 taaatggctt atgggtgtca gcagatggat tagtttatca agactttaat aaggatattc
     6601 attatatttc taaggataaa ttgaatgata ttaattttgt aagatatttt gcaggtgttg
     6661 actggggata tgaacacttt ggagctattg ttgtaattgg tgaggatgat agaggtaatt
     6721 tatatctatt agaagaacat tcagctcaac acaaggaaat tgattactgg atagataaag
     6781 ctaagaatat aaaagagaag tatggaaata taaagtttta ttgtgatagt gctagacccg
     6841 aacacttagc agcatttaaa agaaatggga taaaagcttt caatgctgat aaagctgtat
     6901 tatctggcgt tgaagctgta gctaaaagaa ttaaaactaa tactttattt gtagtttatg
     6961 acaatgttaa tttatttaga aaagaaattt ttatgtatgc ttggaataaa aacacaggag
     7021 aacccattaa aaagtgggat gatgtattag atgcacttag atatgctatc tatacagatt
     7081 ctttaggtac aggaattaaa gtacttacac caaaagggag aaggtgataa attggaatta
     7141 gatgtaataa aaaagttaat tgaacaaact aatagtaaac ataataactt tgttaaaaag
     7201 gctgatgaag ctgaaaaata ctataaaaat caaaatgaca ttataaggga tagaagccct
     7261 aacaatattg ggaaagtaaa tacagccgat aatccattac gaaatgcaga taatagaata
     7321 ccgtttaatt ggtttggttt tttagttaat caaaaaatat catatctatt tacttatcct
     7381 cctacatttg atgttggaga tgatggt
//
LOCUS       DAFAZV010000094         7406 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFAZV010000094 DAFAZV010000000
VERSION     DAFAZV010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7406
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.097"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..338)
                     /locus_tag="KOU88_003821"
     CDS             complement(<1..338)
                     /locus_tag="KOU88_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213637.1"
                     /translation="MKIKKIPESELLVMMYIWDSEDEEVASTEILKTLGEKYEWKKST
                     MLTFLRRLVGRGFLEVVKKDRFTYYKALIEKEEYLKVETKSFFSFFHKNSFESFISAL
                     HDDEEVSENK"
     gene            924..1079
                     /locus_tag="KOU88_003822"
     CDS             924..1079
                     /locus_tag="KOU88_003822"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213638.1"
                     /translation="MGELKLESKMNCTKNKKKVAISIHQMKKISKKDYVFLTDCIETF
                     YMKIKEV"
     gene            complement(1105..1473)
                     /locus_tag="KOU88_003823"
     CDS             complement(1105..1473)
                     /locus_tag="KOU88_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213639.1"
                     /translation="MAEVSKKLKAKEIGKRLNELRTLERLSQRAFGERIFLSQDQISL
                     LEKGKRVLTERSINDICREFEVNEEWLRSGKGEIYKDCLADLEIDDDVKEITNKLYEL
                     EQEDRDAILKMIELLQKKNK"
     gene            1645..1806
                     /locus_tag="KOU88_003824"
     CDS             1645..1806
                     /locus_tag="KOU88_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213640.1"
                     /translation="MICSNKEKVETALMIDYLKKNEPTEWRTIETIISSTYALSNFKK
                     ENKDIMNQK"
     gene            complement(2107..2481)
                     /locus_tag="KOU88_003825"
     CDS             complement(2107..2481)
                     /locus_tag="KOU88_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213641.1"
                     /translation="MEKQNLEDNERRQRLKDIRLSKKLKQKDFGKKLGLSLSQISSYE
                     TGHRKIPQRTINDICREFNVNEQWLLHGEGEMFVDITEDLETSEEIKTMIKKIFALED
                     EDREAIEKIIDNAYLKIKNEEL"
     gene            2635..2811
                     /locus_tag="KOU88_003826"
     CDS             2635..2811
                     /locus_tag="KOU88_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213642.1"
                     /translation="MNQEKEKANDLLLKLELLKKINPQEFGYISGRIDVNIEKLKQET
                     ERNKSKKIRYRKGA"
     gene            2815..3021
                     /locus_tag="KOU88_003827"
     CDS             2815..3021
                     /locus_tag="KOU88_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213643.1"
                     /translation="MTFNKNQIGTAVQLQDIRFDTKVDCIITKVEKNEILVMYYEKET
                     EEIAYKTLTKEDLILDDYKLKLLY"
     gene            3050..3772
                     /locus_tag="KOU88_003828"
     CDS             3050..3772
                     /locus_tag="KOU88_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213644.1"
                     /translation="MDLLKDARKKEWFWLENDLVDREDLSVYEKMAYMVMARYSDDES
                     SCFPSLSLISKKMGCGITTVKKTINSLEEKNLIIKVHRKVKNKKENDTNVYYIMSLKG
                     KSSGDIGHEATDGRSPYDQQVGREATSKKTYNKKTYIKSNTTPQNEPKTDYLDLSFLD
                     LDIEKVKLTKDEYDKLISKFGKKYIHDKIVSLENYIINGKGSRYKSHYRALLTWGNGD
                     ASKGIVPEVTKTKNPLSGFKEL"
     gene            3800..3985
                     /locus_tag="KOU88_003829"
     CDS             3800..3985
                     /locus_tag="KOU88_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213645.1"
                     /translation="MNEKEETVYLNSSNVKLFLGVRDIKEFEELIENVNERICQLQES
                     INKLAQFNIEFDIKSDI"
     gene            4011..4229
                     /locus_tag="KOU88_003830"
     CDS             4011..4229
                     /locus_tag="KOU88_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213646.1"
                     /translation="MKDEKLELTEKDLHCIARHLQNEVMEMVFRGNIEAPTSCEVCDY
                     LQECKDYFTHIDTFIKLSEMTGVDIFTK"
     gene            complement(4248..4460)
                     /locus_tag="KOU88_003831"
     CDS             complement(4248..4460)
                     /locus_tag="KOU88_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213647.1"
                     /translation="MNMCKIKTLREKCSLIDDKVEFSGEYKTFPGFTGSKLLECECNK
                     NYICKIQIMTANSNCPLFKKARQLQY"
     gene            4623..4883
                     /locus_tag="KOU88_003832"
     CDS             4623..4883
                     /locus_tag="KOU88_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213648.1"
                     /translation="MKEEKLELTEKELHCIARHLQNEVMEMVFRGNREAPTSCEVCDY
                     LQECEGDFTCMYHSFTKLSKITGVKVTAFKYCFPDENPKATI"
     gene            complement(4876..5064)
                     /locus_tag="KOU88_003833"
     CDS             complement(4876..5064)
                     /locus_tag="KOU88_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213649.1"
                     /translation="MSQYRVISKECPVINETISLTCEYSAPPGTFGSKLMSTRCDGSH
                     ICDSSSNEECPILKKLLR"
     gene            5202..5519
                     /locus_tag="KOU88_003834"
     CDS             5202..5519
                     /locus_tag="KOU88_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213650.1"
                     /translation="MERKKHELTDQDIQRLIEGLRTDPKIREMIFESKGCETRTSTRS
                     KCEQFVEEKLAYRSYGFETPKYYAKLIADIIDILVYKNVPRDRICGVLYDVERVIPLV
                     VTF"
     gene            5541..6872
                     /locus_tag="KOU88_003835"
     CDS             5541..6872
                     /locus_tag="KOU88_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3213651.1"
                     /translation="MNYSLEAEQNILGSFLINDSIGYKIRELKENDFYFESHKIILSC
                     MKKIIDSNKPLDLLLLKNELEKIDRLVDVGGVSYITSLTTIVITTSNIDHYIKIIKEK
                     LLKRQISELANELINNSNSDTSIDELIVDINDLKALVTTSSSINGNYIDASKIKREKG
                     VHKSIDTGFNKLNNMLDGFRYGTLTILTGKPASGKSTIVNQFIAEAIANKEKAFLYSG
                     ELPSFMAMDWFRKTVANDYHIKEYKSVYGGTYTDIPDYAVELISDWIEDKFFLYDEDA
                     ISDEVNLLNTIEHLYLKKGVRLFVLDNLMTIKTGNKADKYERQEQIVSNLKNLAKKYN
                     LVIVLVAHPRKNMGDMKPTMYDVSGASEIVNYADYILSTYRVIDEEEEADDTYLLILK
                     NRITGKQNISFKMNFSERRKRLYTTSEELNRDYKYDVNKQYVQAEIPEDVF"
     gene            7246..>7406
                     /locus_tag="KOU88_003836"
     CDS             7246..>7406
                     /locus_tag="KOU88_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213652.1"
                     /translation="MIALEKFAGGVLKEKFNTELQKVLDNIADPNTDFKKTRKISLEI
                     VFKANEDRDL"
BASE COUNT         2995 a          904 c         1140 g         2367 t
ORIGIN      
        1 aatttatttt cagacacttc ttcatcatca tgcagagcac ttataaaact ttcaaaagaa
       61 tttttgtgaa agaaactaaa gaaactttta gtctcaactt ttaaatattc ttctttttct
      121 attaatgctt tataatatgt aaatctatct ttcttaacaa cttctaaaaa tcctctacca
      181 actaaccttc ttaaaaaagt taacatagtt gattttttcc attcatattt ttcacctaat
      241 gtttttaaaa tttcagtaga tgcaacttct tcatcttcac tatcccaaat gtacatcatt
      301 accaaaagtt ctgattctgg aatctttttt atcttcataa agcacaccac cttttcaaaa
      361 gtataactaa aatactataa caatagagtt aactatacaa tactaaatgt ctaaaaatgt
      421 tattccaatt tttaccaatt aatttttctt taaaaaaaat ttaagcagga gtaaaaaaaa
      481 taaaaaatta tcaaaattta tcaatataaa aagaaatata agtataaatt tttctctttg
      541 tatattgatt gtatacaatt ctatttttgt aaaattaaat tttacaaaat aatcaaaaat
      601 ggtaaatttt gacatttgcc taatgtcaaa ttaggtgtta caattgtaac ataaagaaga
      661 tatatatcga aataatacat ataaaataca tataaaacta cgtacgtaaa atatttttaa
      721 aaataatcaa aaatcttaat tttcaatatt gaatacaatt aaattttcaa actcatctag
      781 ggcatgacat acaaaagcaa aaaacattaa tttagtatct gataaaaatt taaaaattat
      841 aaaaggggga agtctgttat ttttcagaag caatgtaact gtaaaaatat aaatcagaat
      901 attttgaaaa tatgggggat tctatgggag aattaaaact tgaatcaaaa atgaattgca
      961 ctaaaaataa gaaaaaagtt gctatatcta tacatcaaat gaaaaaaatt tctaaaaaag
     1021 attatgtttt tttaacagat tgcatagaaa cattttatat gaaaataaaa gaggtttgat
     1081 aaattttcaa acctcttttt attgctattt gtttttcttt tgcaataatt ctatcatttt
     1141 caagatagca tctctatctt cttgttctaa ttcataaagt ttgttagtta tttcttttac
     1201 atcatcatca atttctaagt cagctaaaca atctttataa atttcacctt ttccacttct
     1261 tagccattcc tcatttactt caaattctct gcatatgtcg ttaatacttc tttctgtcaa
     1321 aactcttttt cctttttcca ataaagaaat ttgatcttgt gataagaaaa ttctttcccc
     1381 aaacgctctc tgcgaaagtc tttcaagagt tcttaactca tttaatcttt ttccaatttc
     1441 tttagctttt aatttttttg aaacttctgc catttttaca atcctcctct gtcattacta
     1501 tactataaaa acacgacttt gtcattaaaa aaataattat aacgacaaaa tcatgataaa
     1561 aataaaaaag atattgattt ttaacgacaa agtagttata cttaaaataa gttgaacgac
     1621 aaagtaagtg taggaggata aaaaatgatt tgttcaaaca aagagaaagt agaaacagct
     1681 ttgatgatag attatttaaa aaaaaatgaa ccaactgaat ggagaactat agaaaccata
     1741 atctccagta catacgcatt aagtaatttc aaaaaagaaa ataaagacat tatgaatcag
     1801 aaataacaac agtaaatact taaggggagt gataagcttg aaaatttcag attttaataa
     1861 agatcatata ggtaaagcga ttcaactaca agagacaaga tttaatgtca taacggattg
     1921 catcatcaca gaagtagaag taggcgaaat tgttgtaatg ttttacatgc aagaaaatga
     1981 tgacacagga tacaaggcta taacatggga agatttaaaa aattatatca taaatggcaa
     2041 agggaagagg cattatagga tttttgtggc ttgggggatt gttataaaaa gaggtataac
     2101 ctctttttat aactcttcat ttttgatttt tagatatgca ttgtcaatta ttttttctat
     2161 cgcttctcta tcttcatctt ccaatgcaaa tatctttttt atcatagttt ttatttcttc
     2221 actagtttct aaatcttctg taatgtcaac gaacatttca ccttctccat gcaataacca
     2281 ttgttcattt acattaaatt ctctacaaat atcatttatg gttctttgtg gtatctttct
     2341 atgccctgtt tcatatgaag agatttgcga aagagacaaa cctaattttt tgccaaaatc
     2401 tttttgtttt aatttctttg aaagccttat atctttaagt cgttgtcttc tttcattatc
     2461 ttctaagttt tgtttttcca taacgtcacc ccttatgagt ataattataa catttaaaaa
     2521 tacgctttgc aattacaaat tttaaaaaaa tacgcaaaat aaaataaaaa ctcaaagcgt
     2581 attgacatag tatgcaaagc gtaatataat tgaatcacag gaaggagtgt tagaatgaat
     2641 caagaaaaag aaaaagcgaa tgatttgtta ttaaaacttg aacttcttaa aaagataaac
     2701 ccacaagagt ttggatacat aagcggaaga atagacgtaa atattgagaa gttaaaacaa
     2761 gaaaccgaaa gaaataaaag caaaaaaata agatatagga agggggctta aaaattgact
     2821 tttaataaaa atcaaatagg aacagcagtt caattacaag atataaggtt tgatacaaaa
     2881 gttgattgca tcattacaaa agtagaaaag aatgaaatac tagtcatgta ttatgaaaaa
     2941 gaaacagagg aaatagcata taaaactttg actaaagagg atctaatact tgatgattac
     3001 aaacttaagt tattatatta aaaagtaatt tcggaaggga ggtgattaaa tggatctttt
     3061 gaaagatgca agaaaaaaag aatggttttg gctggaaaat gatttggtgg atagagagga
     3121 tctaagtgtt tacgaaaaaa tggcttatat ggtaatggca agatattcag atgatgaaag
     3181 ttcttgtttc ccaagtttat cattaatatc caagaaaatg ggatgcggaa taacgactgt
     3241 caaaaaaaca ataaatagtt tagaagaaaa aaatttaata ataaaagtac atcgcaaggt
     3301 taaaaacaaa aaggaaaatg atacaaatgt ttattacatt atgagtttga aaggtaagtc
     3361 gtctggcgac ataggtcatg aggcgacaga cggtaggtcg ccatacgacc aacaggtagg
     3421 tcgcgaggcg actagtaaaa agacttataa taaaaagact tatataaaaa gtaataccac
     3481 tccacaaaat gaacctaaaa ctgattattt agacctatca tttttagatt tagatataga
     3541 aaaagtaaaa ctaactaaag atgaatatga caaacttata agcaagtttg ggaagaaata
     3601 catacatgat aaaattgtta gtttagaaaa ctatatcata aatggtaaag ggagtaggta
     3661 taagagccac tatagggctt tgctgacttg ggggaatgga gatgctagta aaggtatagt
     3721 accagaagtt acaaagacta agaatcctct tagtggattt aaagaacttt aaaaactaaa
     3781 tagtaaggag gtagatagga tgaatgaaaa agaagagact gtttatttga atagttctaa
     3841 tgtgaagtta ttcttaggcg ttagggatat taaggaattt gaggaattga tagaaaatgt
     3901 caatgagcga atttgtcaac tccaagaatc gattaataaa cttgcccaat ttaatattga
     3961 gttcgatatt aagtcagata tttagttaag tataaattag gaggttgcct atgaaagatg
     4021 aaaagttaga acttactgaa aaagatttac actgtattgc aagacattta caaaatgaag
     4081 ttatggagat ggtgtttaga gggaatatag aagcccctac atcatgcgaa gtttgcgatt
     4141 acttgcaaga atgcaaggac tatttcaccc atatagacac ttttataaaa ttaagtgaaa
     4201 tgacaggtgt agatattttt actaaataaa tttagtaaat taaaatttta gtattgtaat
     4261 tgacgtgctt ttttaaaaag aggacagttg ctattagcag tcattatttg aattttgcaa
     4321 atgtaatttt tattacattc gcattctaaa agttttgatc cagtgaatcc aggaaaagtt
     4381 ttatattcac cagaaaattc aactttatcg tcaataagag agcatttttc tcttaaggtt
     4441 ttaattttgc acatattcat caccacccta taattgattt gaacatactg tcaatatgct
     4501 ccaattaatt ataacatgca aattatcatg gtgtagaatt aaagcatagg tcaattaaat
     4561 ttagttataa aatcaatgaa acagataaag aattaaatgt taaataaatt agggggttgt
     4621 tcatgaaaga ggaaaagtta gaacttactg aaaaagaatt gcattgtatt gcaagacatt
     4681 tgcaaaatga agttatggag atggtgttta gagggaatag agaagccccc acatcatgtg
     4741 aagtttgcga ttacctgcaa gaatgtgagg gagattttac ctgtatgtat cattctttta
     4801 ctaaattaag caaaataaca ggtgtaaaag tgactgcatt taagtattgt tttccagatg
     4861 aaaatcccaa agctactatc taagaagttt ttttagaata ggacattctt cattagaaga
     4921 agagtcgcaa atatgacttc catcacatct agttgacatt aacttagatc caaaagtacc
     4981 tggaggagct gaatattcgc aagtaagaga aatggtttcg tttattacag gacattcttt
     5041 gcttataact cgatattggc tcatactctc accacctttc taattaattt aaacatattg
     5101 gaagtatgtt taaattaatt atagcatgta aattatcatg gtgtagaata gtttcaaatc
     5161 aaaagaagca actaaatagt taaagacagg aggtatgcta agtggaaaga aaaaaacatg
     5221 aacttacaga tcaagatata caaagactta ttgaaggatt aagaactgat ccaaaaataa
     5281 gagaaatgat atttgaaagt aaaggttgtg aaactagaac aagtacaaga agtaaatgcg
     5341 aacaatttgt tgaagaaaaa cttgcttata gaagttatgg atttgaaact ccaaaatact
     5401 atgcaaaact tattgccgac ataattgata ttttagttta caaaaatgtt ccaagagatc
     5461 gtatttgtgg ggtattgtat gacgtcgaaa gggtgattcc tttagttgtg acattttaat
     5521 aataagctgg gggtgattaa atgaattact ctttagaagc agagcaaaac attctaggaa
     5581 gttttcttat aaatgactct ataggttaca aaataaggga attaaaagaa aatgatttct
     5641 actttgagtc acataaaatt attttatctt gcatgaagaa aataattgac tcaaataaac
     5701 cactagatct tttgctttta aaaaatgaat tagaaaaaat agatagatta gtagacgttg
     5761 gaggagttag ttacattacc agtttaacaa ctatagtcat aactacttca aacatagatc
     5821 actatataaa aatcataaaa gagaagttac ttaaaagaca aatttcagag ctagcaaatg
     5881 aattaattaa taattcaaat tcagatacaa gtatagatga attgattgta gatataaacg
     5941 atttaaaagc acttgtgacg acgagcagta gtataaatgg taattatatt gacgcatcaa
     6001 aaataaaacg tgaaaaaggc gtacacaagt ccatagacac gggttttaat aaactaaaca
     6061 atatgctaga tggatttaga tatggaactc ttacaatttt gactggtaaa cctgcatctg
     6121 gtaaatcaac tatagttaac cagtttatag cagaagcaat tgcaaataaa gaaaaagcat
     6181 ttttgtattc tggagaatta ccctctttca tggctatgga ttggtttaga aaaactgtag
     6241 ctaatgatta tcacataaaa gaatataaaa gtgtctatgg aggaacatac acagatattc
     6301 cagattacgc cgttgagctt atatcagact ggatagaaga taaatttttt ctctatgatg
     6361 aagatgcaat aagtgatgaa gtaaatctac taaataccat agaacattta tatttaaaaa
     6421 aaggggttag gctctttgtt cttgacaatc taatgacaat aaaaactggc aataaggcag
     6481 ataaatatga gagacaagag cagatagtaa gcaacttaaa aaatctcgct aaaaaatata
     6541 acttagtaat agttttagtt gcacatccta gaaaaaatat gggtgacatg aaaccaacta
     6601 tgtatgatgt gtctggagca agtgagattg ttaattatgc agattatatt ttatcaactt
     6661 acagagttat tgatgaagaa gaagaggcag acgacactta tttattaatt ttaaaaaata
     6721 gaataacagg aaaacagaat ataagtttca aaatgaattt ttcagaaaga agaaaaagac
     6781 tttacacaac tagtgaagag ttaaatagag attacaaata tgatgtaaat aaacaatatg
     6841 tgcaagcaga aattccagaa gatgtatttt aaaaaaggat aaaaaatagg aaattttatt
     6901 aagtaatgat tttacaataa aaatcaatat tgaataattt aaaaaatcaa tattgaaaaa
     6961 ataccgtttt tcaatattga aattaaaatt tcataaggta ttgaaaatca atattgaaaa
     7021 aaattaataa atatagtaat tgcaatgatt gcagaatacg attacattac acaaaaaaca
     7081 caggtttaaa gaatttgtca aaaactatta aaagatggta atgatagaga gaaaaaaata
     7141 aaatcaaaaa ttttgataaa aatgttatta aattatagtc aaagtttatt aattaatttc
     7201 ctcgtagaaa aatattattt taaataaata aaggagtgat tttacatgat agcattagaa
     7261 aaatttgcag gtggagttct aaaagaaaag tttaatacag agttacaaaa agttttagat
     7321 aatattgcag atccaaatac agattttaaa aaaacaagaa aaattagttt agagatagtg
     7381 tttaaagcaa atgaagatag agatct
//
LOCUS       DAFAZV010000095         7133 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFAZV010000095 DAFAZV010000000
VERSION     DAFAZV010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7133)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7133)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7133
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.098"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..384)
                     /locus_tag="KOU88_003837"
     CDS             complement(<1..384)
                     /locus_tag="KOU88_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head morphogenesis protein"
                     /protein_id="HBK3213653.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSVKYYLELEKQYKLAINSIEKDI
                     LAWYNRFAKNEGISLLEAKKLLNTRELEEFKWSVEEYIKYGKENAINQKWMKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNE"
     gene            complement(374..1816)
                     /locus_tag="KOU88_003838"
     CDS             complement(374..1816)
                     /locus_tag="KOU88_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213654.1"
                     /translation="MLNIYISETDLIKAQLKKESTFNLAKVIEHYILKHRPEKYQEGE
                     AYYYGNANIKNKRRYYILDGAKVDDFTKVNNKAVNNYHKLLVDQKVGYSVGKPIVFNA
                     DDNNFTKLLNELLGEEFDDTITELYLNASNKGIEWLHPYINRKGEFKYVIIPAEEAIP
                     IWDNKRQNELVAFIRFYFIEDIDGNKIKRVEYYTENEVIYFIEKGNSFVQELLYDEYG
                     KLTEIQEGHFRVNNKEQGWGKVPFIPFKNNEKSISDLTFYKSLIDIYDNNISTLADNL
                     DEVQEAMYILKEYGGTDLVEFANNIRYYKAIKVGANGGVDKLEINIPVEAKKELLDRL
                     EKNIIIFGQGVNPESQNTGDKSGVALKFLYSLLDLKCSKTEKKFKKAIRELLWFVCEY
                     LKISGSKSYDYKSVQITFNHSMIINESEKIDMAKKSIGIISDETIVSNHPWVEDVNDE
                     LQRLEKQEDTQKEYDALIPANNQEGVIDET"
     gene            complement(1821..3062)
                     /locus_tag="KOU88_003839"
     CDS             complement(1821..3062)
                     /locus_tag="KOU88_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBK3213655.1"
                     /translation="MAINLEINPDVFNPIYLKHQLNNNNRYQIYFGGSSSGKSFSLAQ
                     RTVLDVFKGNRNYLIVRNVQSTLKRSCLNEITKAISNFKLNEYFQVNKTDMIITCKLN
                     NKQILFCGLDDVEKVKSITPIDGVITDIWVEEATETDYKAVKQLDKRLRGKSKVVKRL
                     TLSFNPILKDHWLYTEYFDIWEDDKQYVEKDNVSILKTTYKDNKFLAEDDIKALENES
                     DKYYYEVYTLGNWGVLGAVIFKNWRVEDFSDIENTFDNFRHGIDWGFADDPFAYVKSH
                     YDRMRRKLYICDEIEAVGLLNREAAPLVSKKANGDLVICDNASPKDVAEFSDLRINAV
                     SARKGAGSIEYGIKFLQGLEIIIHPRCQNFKNEINKYKYKEDKNGNILPIAVDKDNHL
                     IDALRYSLENDMEYGGISFLK"
     gene            complement(3052..3477)
                     /locus_tag="KOU88_003840"
     CDS             complement(3052..3477)
                     /locus_tag="KOU88_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213656.1"
                     /translation="MAKYEYWITEEGLIKIEGWARDGLTDEQIAFNIGINVKTLYDWK
                     KKYSNICNALKKGKEVIDRQVENALLKRALGYEYDEITYEEGQETKRVTKHVVPDTTA
                     QIFWLKNRKPAEWRDKRDIEHSGNLGDITIKVGDEEYGD"
     gene            complement(3534..4499)
                     /locus_tag="KOU88_003841"
     CDS             complement(3534..4499)
                     /locus_tag="KOU88_003841"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213657.1"
                     /translation="MDIKDIKESFQKKPIGWIFGVLIIAIIIIPLIVTFTISVRNPIF
                     SFNESNGWLGFWGSYLGGILGGLATLMAVVITTNQTRVIQEENKEETREIQKENKNIQ
                     NKLIELNENKLLYDLRTIVQDVYIEDNFELKDHRKAMNIDILYLNKSYENLFEKAEYL
                     SRKQKECGEEKKEWESCDDVFCKQICNNLVYFDKYRYLIIKNIGKNPMCYVEIILIGT
                     LCNVNNTQKEKKEQRIKVDFINSNNNVAFPMFEIDDKNEIWNFYSDKSKIIYFTNITG
                     KRERVTLESEQIGEEIKIKTSFEIEDSELKSWEEDASKVMYLQKG"
     gene            complement(4618..5184)
                     /locus_tag="KOU88_003842"
     CDS             complement(4618..5184)
                     /locus_tag="KOU88_003842"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213658.1"
                     /translation="MLNQFNEFLGNYINIISVIASFASIAALIISIIAFMESNKQAKL
                     ILKYRRNNENNMAGDYYENGNGYIRLDLNKIDNKSNVYAEIRSNNLVDFVIENKSKIV
                     AKSPILSLKFINMEVDIEENNNFEQINSELRWHPKDNTTIHKGINFRIEQFNFKNCVM
                     LKKEAYIEVVLSADNMETKEFSIPIKAY"
     gene            complement(5634..5846)
                     /locus_tag="KOU88_003843"
     CDS             complement(5634..5846)
                     /locus_tag="KOU88_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003438585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213659.1"
                     /translation="MKCPNCGSENIEQGISTVSESGFVTYRTGLEYNTRFSTKVSKTY
                     SDLCLDCGEIVRTYIKGETDRNWCKD"
     gene            complement(6049..6295)
                     /locus_tag="KOU88_003844"
                     /pseudo
     CDS             complement(6049..6295)
                     /locus_tag="KOU88_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424164.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6330..6533)
                     /locus_tag="KOU88_003845"
     CDS             complement(6330..6533)
                     /locus_tag="KOU88_003845"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213660.1"
                     /translation="MNMINLREKIIKELNEFNIKADNVFLEYAVKHIENFMNEGIDDE
                     ELLIRGVVLGASYVVNIENKDLD"
     gene            complement(6681..>7133)
                     /locus_tag="KOU88_003846"
     CDS             complement(6681..>7133)
                     /locus_tag="KOU88_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213661.1"
                     /translation="VRELRKEEREDRKKGVLYNTRLLMKHYNDFKRHINSAVSEAKEV
                     NYLEEDLSDFEDEELYILSIKKSKTRTIIMIAHIDSALKTLKLRQERLQSYEKYRALE
                     LYYFDEKTYEEIAEILNCGVVTSRRWVNEMITELGIYLFGVDGLKSIV"
BASE COUNT         2219 a         1326 c          614 g         2974 t
ORIGIN      
        1 ttcatttcca tataaaactt ctacttgttg ctgtatttgt aactttaaag cttcaagtct
       61 tgttatatga actcttgcac tagcattttc taactctttc atccactttt gatttatagc
      121 attttcttta ccatatttaa tatattcttc aacgctccat ttaaactctt ctagttctct
      181 tgtatttagt agtttcttag cttctaataa agatattcct tcatttttgg caaatctgtt
      241 gtaccatgct aatatatctt tttctatact atttatagct agtttatatt gcttttctaa
      301 ttcaagataa tattttacac ttttgttatt ttgagcttct tctaactgtt cgaatctctt
      361 cctccaataa tctttatgtt tcatctataa caccctcttg attattagca ggaattaaag
      421 catcatactc tttttgagta tcttcctgtt tttccaacct ttgaagttcg tcattaacat
      481 cctcaaccca aggatggttg gaaacaatag tttcatctga tataattcca attgatttct
      541 ttgccatgtc tattttttca gactcattta ttatcataga gtgattaaat gtaatttgaa
      601 ctgatttata atcatagctc ttactaccac ttatctttaa atactcacac acaaaccata
      661 aaagctctct aattgctttt ttaaacttct tttcagtctt agaacattta aggtccagta
      721 atgaatataa aaatttaagt gctacacccg atttgtcacc tgtgttttga gattctggat
      781 taactccttg accaaagata attatattct tttccaatct atcaagaagc tcctttttag
      841 cttcaactgg tatatttatc tccagcttat ctacccctcc attagcgcct accttaatgg
      901 ctttataata tcttatgtta tttgcaaatt ctactaaatc agtacctcca tactctttta
      961 gtatgtacat agcttcttgt acttcatcta ggttatctgc aagagtagaa atgttattat
     1021 catatatatc aattaaagac ttgtaaaaag ttaaatcaga tatgcttttc tcattgtttt
     1081 taaatggtat aaatggaact ttaccccatc cttgctcttt gttatttact ctaaaatgac
     1141 cctcttgtat ctctgttaat tttccatatt catcatataa aagttcttga acaaaactat
     1201 ttcctttttc aataaagtaa attacttcat tttctgtata gtattcaact ctttttatct
     1261 tatttccatc tatatcctca ataaagtaaa atctaataaa ggcaactaat tcattttgcc
     1321 tcttgttatc ccaaatagga atagcttctt ctgctggtat tattacatat ttaaactctc
     1381 cttttctatt aatatatgga tgtaaccatt ctattccctt attgcttgca ttgagataga
     1441 gttctgttat tgtatcatca aattcttctc ctaataattc atttaaaagc ttagtaaaat
     1501 tattatcatc tgcattaaat actattggtt ttccaacact gtagcctacc ttttggtcaa
     1561 ctaaaagctt atgataatta ttaactgctt tattattaac tttagtaaaa tcatcaacct
     1621 tagcaccatc taaaatataa tatcttcttt tattttttat attagcatta ccataatagt
     1681 atgcttctcc ttcttgatac ttttctggtc tatgctttaa aatataatgc tctataactt
     1741 tcgccagatt aaaagtactc tcttttttta gctgagcttt tattaaatct gtttcactta
     1801 tataaatatt taacacctcc ttactttaag aagcttattc ctccatactc catatcattt
     1861 tctaaactat atcttagtgc atctattaaa tgattatctt tatctactgc aataggtaag
     1921 atatttccat tcttatcctc tttatattta tatttattta tctcattttt gaagttttgg
     1981 catcttggat gtattataat ttcaagccct tgtaaaaatt tgataccata ttcaatagaa
     2041 ccagctcctt ttcttgctga aactgcattg attcttaagt cactaaattc agctacatct
     2101 tttggacttg cattatcaca gataactaaa tctccattcg cttttttact aactaaaggt
     2161 gcagcttctc tatttaataa tccaactgct tctatttcat cacatatata taattttctt
     2221 ctcatcctat catagtgtga ttttacatat gcaaatgggt catcagcaaa accccagtca
     2281 attccatgcc taaagttatc aaatgtattt tcaatatctg agaaatcttc aactctccaa
     2341 ttcttaaata tgacagcacc aagtacgccc caatttccaa gagtgtaaac ttcataataa
     2401 tatttatcac tttcattttc taaagctttt atatcatctt ctgccaagaa tttattatct
     2461 ttatatgtag tttttagaat acttacatta tctttttcta catactgttt atcatcttcc
     2521 catatatcaa aatactctgt atatagccaa tggtctttaa gtattggatt gaagcttaat
     2581 gttagtcttt ttactacttt agactttcct ctaagtctct tatcaagttg tttgacggct
     2641 ttataatctg tctctgttgc ttcttctacc catatatcag ttattacacc atctattgga
     2701 gttattgatt taactttctc aacatcatct aagccacaaa ataatatctg tttattattt
     2761 agcttacaag ttattatcat gtcggtttta tttacttgaa aatactcatt taacttaaaa
     2821 ttactaatag cctttgttat ctcatttaaa caagacctct ttagagtgct ttgaacattt
     2881 ctaacaatta aataattcct attcccctta aatacatcta atactgttct ttgagctaaa
     2941 gaaaaagatt tacccgatga tgaaccacca aagtaaatct gatacctatt gttattatta
     3001 agttgatgct tcaaatatat tggattaaat acatctggat taatttctaa attaatcgcc
     3061 atattcctca tcacctacct ttattgtaat atctcctaga ttaccactat gttcaatatc
     3121 tcttttatcc ctccattcag ctggttttct atttttcaac cagaatatct gtgctgtagt
     3181 atctggtacc acatgtttag ttactctttt agtttcttga ccttcttcat atgttatctc
     3241 atcatattca taacctaacg ctctttttaa tagggcattt tcaacctgcc tgtcaattac
     3301 ttcttttccc ttttttaagg cattacaaat attactatat ttctttttcc agtcatatag
     3361 tgttttgaca tttattccaa tattaaatgc tatctgttca tctgtaagcc catctctcgc
     3421 ccatccttca atcttaatta atccttcttc tgttatccag tattcatatt tagccacatc
     3481 accacctcgt ttttgtttgt tttgaggata aaaaaagaac tctgtttaga gttctatccc
     3541 ttttgcaaat acattacctt tgatgcatct tcttcccaac ttttaagttc actatcctca
     3601 atctcaaaac tagtttttat ttttatttct tctcctattt gttcactttc taaagttact
     3661 ctttctcttt tgcctgtaat gttagtaaaa taaattatct tgctcttatc actataaaaa
     3721 ttccatatct cattcttatc atcaatctca aacattggaa atgcaacatt attattagaa
     3781 tttataaaat ctacttttat cctctgctct ttcttttctt tttgagtgtt atttacatta
     3841 cataaagttc ctatgagtat aatctctaca taacacattg gatttttccc aatatttttt
     3901 ataattaaat atctatattt atcaaaataa actaaattat tacatatttg cttacaaaaa
     3961 acatcatcac atgattccca ttctttcttt tcttcaccac attctttttg ctttcttgat
     4021 aaatattcag ctttctcaaa taagttctca tagcttttat ttaaatataa tatatcgata
     4081 ttcatagctt ttctatgatc tttcaattca aagttatcct ctatatatac atcttggaca
     4141 atagttctta aatcatataa caatttattt tcattaagct caattaattt attttgaata
     4201 tttttatttt ctttttgtat ttctctagtt tcctctttat tttcttcctg tattactctt
     4261 gtttgattag ttgtaataac aacagccata agtgttgcta atcctcctaa aataccacct
     4321 aaataacttc cccaaaaacc taaccatcca ttgctttcat taaaactaaa aatcggattt
     4381 ctaactgaaa tagtaaatgt aacaataagc gggataatta taattgcaat aatcaacacc
     4441 ccaaaaatcc atcctatagg tttcttttga aaactttctt ttatatcttt tatgtccatt
     4501 ctcatcccct ccaaagtata aaattcaact tcaaaggtca atatccttca aaaactattc
     4561 gacaactaca aaataatcaa attttcacta aaaaaagaac tcttgttatt gagttcttta
     4621 atacgctttt attggtatac taaattcttt tgtttccata ttatcagctg ataatactac
     4681 ttctatataa gcttcttttt taagcataac acaattttta aaattaaatt gttctattct
     4741 aaaatttatt cctttatgaa ttgtagtatt atcttttgga tgccatctaa gttcactatt
     4801 tatttgttca aagttattat tttcttcaat atctacttcc atattaataa atttcaaact
     4861 taatatagga ctttttgcaa caatcttact tttgttttct attacaaaat caactaagtt
     4921 attactacga atttcagcat aaacattaga tttattatct atcttattta aatcaagtct
     4981 aatatatcca tttccatttt cataataatc accagccata ttattctcat tatttcttct
     5041 atattttaat atcaatttag cttgtttatt agattccata aaagctataa ttgatataat
     5101 caaggctgct attgatgcaa aggatgcaat tacagaaatt atatttatat agttaccaag
     5161 aaattcatta aactgattga gcatattttt tctccttaaa aacattacct tatcttatta
     5221 tatttgtata atatttttta catttacttt taatttatta cacaaacttc ctacataaaa
     5281 aaagaccatc tataaagacg attctctaga ctaagtatct atgtttttgc ttgtactctg
     5341 taacagcatc atttcatgct tcttgctctc ttattccttt ttctctagca attctttgtg
     5401 ctatctttct aactaattca gcacttttta atattcctat actaaccact tccttatctc
     5461 tattctacat tataccatat aataaagaat aaagctaatt cctattaagt tctgttactc
     5521 tgtttcacaa gttcaaaacc ttaaccctat aacatattta tcattatctt tttaatttat
     5581 tgcataaaaa agaccatcta taaagatagt ctaaatctta tgtattttta tttctaatct
     5641 ttacaccaat tcctatcagt ctcacccttt atataagttc taactatttc accacaatct
     5701 aagcataagt cagaatatgt tttagatacc ttagttgaaa atcttgtatt gtattctaaa
     5761 ccagttctat atgtaacgaa tcctgattca ctaactgtag aaataccttg ttctatattt
     5821 tcgctaccac aattaggaca tttcatattt atacccccta ataattactt tctttcatat
     5881 taccataata aaagtaatct tttaatttta tttcttcatt acactagtta tccaatatcc
     5941 aatacaataa gacataaaat aatatgataa atacaacgcc atttcagtac tatcaaatct
     6001 tagatacatc atgataacaa ctgaacctaa aagtgatatt aaagctggaa ttttccaatt
     6061 tatttgtttt ttagcacata ttataccatt aactaaaaat gaaactggta tatacaatac
     6121 tacacctgaa ataaggattc cttttatatc catctcactt aatcctaaac tattagttat
     6181 tgtattttca aatgatagaa aaaatattat aatcattgtt aataatggta gcaatactcc
     6241 taagatattt ttcttcatag ttatcacccc taattcattt agtacatttt accacaaact
     6301 taacctataa aatgtaaaag acctagaaat taatctaagt ctttattttc tatattaact
     6361 acataactag ctccaagcac aacacctctt attaataact cttcatcatc tataccttca
     6421 ttcataaaat tttcaatatg tttaactgca tattctaaaa aaacattatc tgcttttata
     6481 ttaaattcat ttagttcttt tattatcttt tctcttaaat taatcatgtt cattttttat
     6541 tctcctttgt tgtaaatata aaaaagacta agttaggggt acttagtctt ttttaaggag
     6601 tatattatac acttgtttca tactaccatt ataacaggat taaaatatca ttaaaatatc
     6661 atctttttat catatattta tcaaacaatt gattttagac catctacacc aaataaatat
     6721 ataccaagct ctgttatcat ctcattaacc caacgtcttg atgtaactac tccacagttt
     6781 aatatttctg ctatttcttc ataagttttt tcatcaaaat agtaaagctc taatgctcta
     6841 tatttttcat atgattgtaa tctctcttgt cttaacttta atgtttttaa tgctgaatct
     6901 atatgagcta tcataataat agttcttgtt ttactttttt taatacttaa aatatacaac
     6961 tcttcatctt caaaatcaga caaatcttct tctaaataat ttacttcttt agcttcactt
     7021 actgctgagt ttatatgtct tttaaaatca ttataatgtt tcattaataa tctagtatta
     7081 tataagactc ctttttttct atcttctctt tcttcttttc tcaattctct tac
//
LOCUS       DAFAZV010000096         7098 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFAZV010000096 DAFAZV010000000
VERSION     DAFAZV010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 7098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7098
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.099"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            75..251
                     /locus_tag="KOU88_003847"
     CDS             75..251
                     /locus_tag="KOU88_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213662.1"
                     /translation="MFRDKMDKCTHMLTAYIGSSYDYCDFIDTQLDDFILEYGEKVVE
                     SCLHQVMVLVSKYN"
     gene            476..676
                     /locus_tag="KOU88_003848"
     CDS             476..676
                     /locus_tag="KOU88_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003723180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK3213663.1"
                     /translation="MNNGIVKWFNNEKGFGFISMESGDDVFAHFSAIQTSGFKSLEEG
                     QKVSFDIVKGARGPQAENITIL"
     gene            1311..2123
                     /gene="modA"
                     /locus_tag="KOU88_003849"
     CDS             1311..2123
                     /gene="modA"
                     /locus_tag="KOU88_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK3213664.1"
                     /translation="MFKKLSVLALAMIISLSITACNSKENKANDESNTKVTTADDSKE
                     KETLFVYSGAGLKKPMDEIAKKFEKENNVKVEYSYAGSAQLIAQIETSHKGDVFIVGS
                     EPIYSKAFEKELVGEHKTVAHHTPAIVVPKGNPANIQKLEDLNKDGVKLILGDKESNA
                     IGKTTQKILEKNNLKSINDNVVSTAATVNEMIVQLTSSKADATIATKDSVFGNEDVEV
                     IEIAQDKNIDQLISAGIVNYSDKKDLANKFINYIESDEAKQIFKKYGFEPVK"
     gene            2133..2924
                     /locus_tag="KOU88_003850"
     CDS             2133..2924
                     /locus_tag="KOU88_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213665.1"
                     /translation="MKNKFFTTLLTGFFAIVFLFIVSPLLMLIIKGISYVPICLKSVE
                     VQYAITLSIKTSLISTIVCLLLAIPVAYFLHITKLPFKKLIIQIINLPMSLPHLVSGI
                     ALLLLFGRMGIGDSIYKIFKLDFIFTKQGIVLAQVFVNLPLTIKILHTSLNESNEKMI
                     FVARTLGRNSWEAFRFIILPNLKTGIISATVMTWSRALGEFGAVAMIAGSTRMKTEII
                     PTSIYLNMSTGDIDIAIGIAVILIFISLTCLMLFEIFFNREVDKN"
     gene            2926..3621
                     /locus_tag="KOU88_003851"
     CDS             2926..3621
                     /locus_tag="KOU88_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK3213666.1"
                     /translation="MLKIKNLSLDLPNFKLQENSLNINNHEYFVLLGASGSGKTLFLE
                     TLAGRYPSAKGNVSYKENLISNLPPENRNIGFVYQNFELFPNMNVEDNIRFPLKLRKI
                     PIDEQILKANHLSKLMQIEDIKNRYPKNLSGGEKQRVAFARALIAKPDILLLDEPMSS
                     LDYITKKHISKILKDVYIKYKPTVIHVTHDISEAMFFAHKIGIMNNGKINHIFDLNEE
                     IKNKGESFFYEYI"
     gene            3608..4339
                     /locus_tag="KOU88_003852"
     CDS             3608..4339
                     /locus_tag="KOU88_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213667.1"
                     /translation="MNIFDILRDYLLVQVDKYNLNMDMISIVSKSLSSKEAIGNTKRK
                     DFPIIVGKEIMLEADFKGAKGQAFTSTPSTFEGSLKDILSLDLHDNPHDRSLFIASLN
                     AVMKYLGKTDRTIHCKNNEPEVCAKKFPEFIKMEFGNPKVAIIGYQPAIIDNIKDFFE
                     TRVLDLNPEFVDTIQYNVKIEDGIRDYEDVISWADLVICTGSTLCNNSIINFLSLNKP
                     VYYYGTTIAGASNILGLKRLCFCSK"
     gene            4653..5453
                     /locus_tag="KOU88_003853"
     CDS             4653..5453
                     /locus_tag="KOU88_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBK3213668.1"
                     /translation="MTFKNKKFTINKYKILSIILVLCLILTAFSSYVNYSHKKFKDYV
                     VFYVQHQDDEVLWAGSAIVNAIKERGKNHVFVVLVSTGCGISVFDKYKKYENLTNIQK
                     SEYRNREFLASLNSLGVIRENIILLPETNTNGNTDFNYMEKIALTFEEKFKNVTHIAH
                     TYKLDDHLQHLKNGSVIQNLYNAGKIKDAKYFVKPKFADKITFNNKIVYKAHSTEDYE
                     KVKNACQQYKIVDELEYREGIGYKSDHKSFDKLLNNKDVPAILHTPNL"
     gene            5993..6709
                     /locus_tag="KOU88_003854"
     CDS             5993..6709
                     /locus_tag="KOU88_003854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213669.1"
                     /translation="MNQNILVVDDDREIVDAIEFYLRPDNFNVLKAYDGLEALDILIE
                     NDIKLIIMDVMMPNLDGLKTTLKIREKRNIPIILLSAKSEDMDKIIGLNMGADDYITK
                     PFNPLELTARVKSQLRRYINLGDFSNTNNSNDTNYILKSGGLELNTDTKIVSLDGEEI
                     KMTPLEYKILTLLMSRKGKIFSSHEIYENVWNEDAYSCERTIAVHIRRIREKIEINPK
                     EPKYLKVVWGIGYKIEKLNY"
BASE COUNT         2780 a          828 c          988 g         2502 t
ORIGIN      
        1 ttatgtcagc cagttgccaa aaagatattt tctttttgtt tttcatgaaa gttttttagg
       61 gggataaata cattatgttt agagataaaa tggataaatg tacacatatg ttaactgctt
      121 atattggtag ttcatatgat tattgtgatt ttatagatac acagttagat gattttatat
      181 tagagtacgg agaaaaagtt gtggaatctt gcttgcatca agtgatggta ttggtaagta
      241 agtataatta gacagatttt tttctagaaa acccttttta gttttatcta catttacatt
      301 aatatattgg taatataaaa tgtttaaatt tattttcata ttaagaataa ataaaaatgt
      361 taactaaaaa ttataattaa atagacattt atgttaatct atgatacaat agtatttgtg
      421 gtaatacaca agtaaatcaa gtatatcttg atataggtta ataggagtat ttttaatgaa
      481 taatggaata gtaaaatggt ttaataatga aaaaggattt ggatttatat caatggaaag
      541 tggagatgac gtatttgctc atttctcagc tatacaaact tcaggattta aatcattaga
      601 agaaggtcaa aaagtaagct ttgatatagt taaaggcgct agaggtcctc aagcagaaaa
      661 tataactata ttataatata tagatttttc ggaaagactc ttttaagagt ctttttttta
      721 tttacgcatt ttgtaaaaaa ggaaaaaata acttcaacaa aaaaatactt aaaaataata
      781 cttagtctaa atacttttta taaaataaat ctgacaaaaa tatatttata aagtatgtac
      841 ttaaacctac aagtactctt ttaattagaa tatatagtaa tataataatt ttagttgtgg
      901 cacatcaaaa ttttcaacta tctcataaat acatactctt tcttttgtat tcaattctga
      961 tataacactt ttagtaattt attaataaaa aacaattaaa acatatctat atgtttcaat
     1021 gttctatttt ttcactgaaa tataataaat ataaaattag ttaaaaagta aaaaatctac
     1081 aataagttaa tttgatttaa gtttttaaat ttaaaatact ttaaagtatt aataaaaatt
     1141 aaaaataaaa taactaccta tggaaatgac attataaata gattttttct taactataca
     1201 taacaaaaca taacaaaaca ttataaaaca taacaaaaac ttagacatcg ttttcttagt
     1261 atgatatact aaaaaagaat ttacactaat ttactaaggg ggaatatctt atgtttaaaa
     1321 aactttcagt actagcttta gctatgatta tttcattaag tattactgca tgtaattcta
     1381 aagaaaacaa agctaatgat gaatctaata ctaaagtgac aacagctgat gattcaaaag
     1441 aaaaagagac tctttttgtc tattcagggg caggtttaaa gaaaccaatg gatgaaatag
     1501 caaaaaaatt tgagaaagaa aataatgtca aagttgaata tagctatgca ggttctgcac
     1561 agctaatagc tcaaattgag acaagtcaca aaggagacgt atttattgtt ggttctgaac
     1621 caatttattc aaaggccttt gaaaaagaac ttgtaggtga acataaaacg gttgcacatc
     1681 atacacctgc aatagttgta cctaaaggaa atccagctaa tattcaaaaa ttggaagact
     1741 taaataaaga tggagttaaa cttattttgg gagacaaaga gtctaatgct ataggtaaaa
     1801 ctacacaaaa aatacttgaa aaaaataatt taaaatctat aaatgataat gttgtctcta
     1861 cagctgcaac tgtaaatgaa atgattgtac agttaacatc aagtaaagct gatgctacaa
     1921 tagccacaaa agattcggtc tttggtaatg aagatgtaga agttatagaa attgcccaag
     1981 ataaaaatat agaccaactt atatcagcag gaatcgtaaa ctatagtgat aaaaaagatt
     2041 tagctaataa atttataaat tatatagagt cagacgaagc taaacagata tttaaaaaat
     2101 atggttttga acctgttaag tagtgattaa acttgaaaaa taaatttttt actactctac
     2161 ttactggatt ttttgctata gtctttttgt ttattgtatc accacttctt atgttaatca
     2221 ttaaagggat aagttatgtt cctatatgct taaaatcagt ggaagtacag tatgcaataa
     2281 cacttagtat taaaacatct ttaatatcta ctatagtatg ccttttatta gctattccag
     2341 tagcatattt tttacatatt actaaattgc catttaaaaa actgattata cagataataa
     2401 atctccctat gtctcttcca cacttagtat caggaattgc tcttttactt ttgtttggaa
     2461 gaatggggat tggagattcc atttataaga tttttaagct tgattttata tttacaaagc
     2521 aaggtatagt tttagcacaa gtatttgtaa atcttccact tactattaaa atacttcaca
     2581 cttcactaaa tgaaagtaat gaaaagatga tatttgttgc acgtaccctt ggacgtaata
     2641 gttgggaagc atttagattt ataattcttc caaatctaaa aactggaatc atatctgcaa
     2701 ctgtaatgac ttggtcaaga gcacttggtg aatttggtgc agtagctatg atagcaggtt
     2761 ctacacgtat gaaaactgaa attattccta catctatata tttaaatatg tctactggtg
     2821 atatagacat tgcaatcgga atagctgtaa ttttgatatt tatctcactt acatgcttga
     2881 tgctttttga gatatttttt aatagagagg ttgataagaa ttaatatgtt aaaaataaaa
     2941 aatttatctc ttgatttacc taattttaaa ttacaagaaa atagtttaaa tattaataat
     3001 catgaatact ttgttttatt aggagctagt gggtcaggta aaactctatt cctagaaaca
     3061 ttagcaggaa gatatccatc tgctaaagga aatgtatcat acaaagaaaa tttaatatca
     3121 aacttacctc cagaaaatag aaatatagga tttgtatatc aaaattttga attatttcca
     3181 aatatgaatg ttgaagataa tataaggttt ccacttaaat taagaaaaat acctatagat
     3241 gaacagattc ttaaggctaa ccacttgtct aaattaatgc agatagaaga tataaaaaat
     3301 aggtatccta aaaatttaag tggaggcgaa aagcaacgag ttgcttttgc acgtgcctta
     3361 atagctaaac ctgatatatt acttttagat gaacctatga gttcattgga ttatattaca
     3421 aaaaaacata taagcaaaat tttgaaggat gtctacataa aatacaaacc aacagtgatt
     3481 catgttactc atgatatttc tgaagcaatg ttttttgctc ataagatagg aataatgaac
     3541 aatggaaaaa taaatcatat ttttgattta aatgaagaaa taaaaaataa aggagaatct
     3601 tttttctatg aatatatttg atattttgag agattatcta ttagtacaag tcgataaata
     3661 taatttaaat atggatatga taagtattgt gtccaaatct ctatcttcaa aagaagcaat
     3721 tggaaatact aagcgtaaag attttccaat tatagttggt aaagaaataa tgcttgaagc
     3781 tgactttaaa ggagctaaag gacaagcatt tacttctact ccatctacat ttgaaggttc
     3841 tttaaaagac atattatcat tagatttaca tgacaatcct catgatagaa gtctttttat
     3901 agcatcatta aatgcagtta tgaaatactt aggcaagacg gatagaacca ttcattgtaa
     3961 aaataacgag ccagaggtat gtgcaaaaaa attccctgag tttataaaaa tggaatttgg
     4021 taatccaaaa gtagcaatta taggatatca accagccata attgataata ttaaggactt
     4081 tttcgaaaca agagtattag atttaaatcc tgaatttgtg gatactattc aatataatgt
     4141 taagattgaa gatggtatac gagattatga agatgtaata tcttgggctg atttagtgat
     4201 ttgcacagga agtacattat gtaataactc aattataaat tttctatcac ttaacaaacc
     4261 agtttactat tatggaacta cgatagctgg tgcatcaaat attttaggtt taaaaagact
     4321 ctgtttttgt agtaaataag caatcatatc atcaaggagt acacaaatat atatgtgtac
     4381 tctttaaatt taaaaagtta ttacttttat tctaagtact aaagtaaaat tctattaaaa
     4441 tgaatcccga ataaatgtac aatcccttta aatctcaatt cctatcaatc attaatattt
     4501 tgattagtct tatacataaa tgttttcttt attttaaact aataaaaaaa ttttattcca
     4561 ttaatctact ctatattttt cagcatttaa gaaataattt ttagtacttt gtttgataat
     4621 ataactaaga caacttttca ggagatgatt aaatgacatt taagaataaa aaatttacta
     4681 taaataaata taaaattcta tctattattc tagttttatg tttgatttta accgctttta
     4741 gtagctatgt gaattatagt cataaaaaat ttaaagatta tgttgtcttc tatgttcaac
     4801 atcaagatga tgaagtgttg tgggctggga gtgctattgt taatgctata aaagaaagag
     4861 gaaaaaatca tgtatttgtg gttttagtat ctactggatg tggtatatcc gtctttgata
     4921 aatataaaaa atatgaaaac ctaacaaata tacaaaaatc agaatataga aatagagaat
     4981 ttttagcttc tcttaatagc cttggcgtaa taagggaaaa tataatatta ttaccagaaa
     5041 caaatacaaa tggtaatact gacttcaatt acatggaaaa aattgctctt acatttgaag
     5101 aaaaatttaa aaatgtaact catatagcac atacttataa gttagatgac catttacaac
     5161 atttaaaaaa tggttctgtt atccaaaatt tatataatgc tggtaaaata aaagatgcta
     5221 aatattttgt aaaacctaaa tttgctgata aaataacttt taataataag atagtttata
     5281 aagctcattc tactgaagac tatgaaaagg ttaaaaatgc ctgtcaacaa tacaaaattg
     5341 ttgatgaatt agaatataga gaaggtattg gctataagtc tgaccataaa tcatttgata
     5401 agttattaaa taataaagat gttcctgcta tacttcatac acctaattta taagaaatat
     5461 ttattctttt aatttaagtt ataaaaagga aattatttga gattttgtga tatagcactt
     5521 tttgtgctat actacttttt ctcatacaac tattacccat atctaatttc atcatctctt
     5581 aaaatatata aagatatcat cattaaaacc tataagcctt attaaatgct ttatacatac
     5641 ctacattaaa ctacctgttt atattaaact acattaaaat aaatatttgt tataaattct
     5701 taataattat gaaactcatt tgttatttat atttgttaat atatgtttaa acctaaaaaa
     5761 ttaataaacc aaaataacat aagaagtgtg atagattacc ctagatattt tcataaactt
     5821 ttaccttcag attaatatgg gcgtctatac ttttaaattt actatatgca ttgacaatat
     5881 attaaaagta ctagttttta tttcataatg aatgggctta ctgttttcta atacctcttt
     5941 ttggtataaa ataaaaattg gttaaaaata aaatttcaag ggggttaata agttgaatca
     6001 aaatatattg gttgtagatg atgatagaga gatagttgat gctatagagt tctatttgag
     6061 acctgataac tttaatgttt taaaggcata tgatggactt gaagcattgg acatactaat
     6121 cgaaaatgat attaagttaa taataatgga tgtaatgatg cccaatttag atgggcttaa
     6181 aactacactt aaaataagag aaaaaaggaa tataccaata attctcttat ctgcaaaatc
     6241 agaagatatg gacaaaatta taggtcttaa tatgggtgct gatgactata taactaaacc
     6301 atttaatcca ctagaactta ctgctcgagt aaaatctcaa cttagaaggt atataaattt
     6361 aggtgatttt agtaatacaa ataactcaaa tgatactaat tatattctaa aaagtggtgg
     6421 cctagagcta aatacagata caaaaatagt ttctttagat ggtgaagaaa ttaaaatgac
     6481 accacttgaa tataaaatac ttacacttct tatgtcacga aaaggtaaaa ttttctcttc
     6541 tcatgagatt tatgaaaatg tctggaatga ggatgcttat agttgtgaga gaactattgc
     6601 tgttcatatt agaagaatta gagaaaagat tgaaattaat ccaaaagaac caaaatattt
     6661 aaaggtggtg tggggcattg gttacaaaat tgaaaaactt aattattaat gattctaaag
     6721 caaaatttat tttattatta ttactgtttc tattagtttc tatattattt gaagcagttt
     6781 atgatttgaa taataacttt tctaatatta attattatta tagagagttt gctctccctt
     6841 atttttattt tttcggtact cctgtacatt tgtcaaaagt agaattagag tttgtctgca
     6901 taggtattat attatcaagt tttttattga ctatactatg ttttacattg tataaaaaaa
     6961 ataaacaaac taaagtcaaa ttcttagaga atgtcataag ccttttttct aaggtaaaaa
     7021 tagaacttac acttatatta actttgatac tattaacctt aaggtttcat gcatttacaa
     7081 gtaataaaat attttaca
//
LOCUS       DAFAZV010000097         6504 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFAZV010000097 DAFAZV010000000
VERSION     DAFAZV010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6504
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.100"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..357
                     /locus_tag="KOU88_003855"
     CDS             <1..357
                     /locus_tag="KOU88_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBK3213670.1"
                     /translation="RQEPSKTFKLNIEKSKIDGICDDVEALKQTIFLILNTERYQHLI
                     YSWNYGVELNDLIGEPISFVIPELERRIKEALIQDDRIENVDNFEFENIKGKVNCKFM
                     VHTKYGNIKAERVVSV"
     gene            357..1406
                     /locus_tag="KOU88_003856"
     CDS             357..1406
                     /locus_tag="KOU88_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBK3213671.1"
                     /translation="MFEFMTFENIIKRMLDSVPSTLDKREGSIIYNALAPVAIELSET
                     YIAMDELLDQTFVDTASYYYLEKRCKERGITPLEATNTIAKGVFNIDIPLDSRFNLGE
                     YNYVAIERISECIYKMKCETAGPIFELGQLIPIEYIDKLETAELTEILINGEDEESED
                     SLRQRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKV
                     PSEDLVNLVQEEIDPIGHQGQGLGLAPIGHRVTVEGVTSTTINISAEITYKSGYTWEN
                     IKTIAEEAVDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINSIASNL
                     NVDKDSIVLRGEVVG"
     gene            1399..2016
                     /locus_tag="KOU88_003857"
     CDS             1399..2016
                     /locus_tag="KOU88_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBK3213672.1"
                     /translation="MDKEINLINYLPQILRDKEEYIKVFNVENKEIKTLHEKLNDLSN
                     DQFLEDLTPSGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNFGITTLMGQEITIYPWSPPDIETYGEIDVLTGNGVGYQEITIF"
     gene            2028..3053
                     /locus_tag="KOU88_003858"
     CDS             2028..3053
                     /locus_tag="KOU88_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3213673.1"
                     /translation="MAIDKSYYTIITDVGKAKIANASVTGNKVGFVKIQLGDGGGSEY
                     TPTESQTALKNVVWEGNIGNTTTDETAPNCIILESLIPSSVGGFMIREIGYLDDENNL
                     IAISKYKECYKPSIEQGAVVDMKVKTVLIVSNVNNIELKIDPTIIFATLKDIQDLETK
                     IGTVNTKIDTTKTELTNNLETAKTELNTRIDTENEKQNIKIDQLIAGGSNVASTQTIT
                     IDDWVEDAENGFKATVTHSLLTQRIVVNIIDATTKENVVTNFKIIDDNSIEVRSETRS
                     ELNVYVINGNAETHFINATVDDNRVSEMTTYSSKKIEDRFLNLEEKVNGGISSIATSV
                     NELITYC"
     gene            3070..4728
                     /locus_tag="KOU88_003859"
     CDS             3070..4728
                     /locus_tag="KOU88_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213674.1"
                     /translation="MQTEWNFDYIGAGKKVTLKPGKYKLECWGASGGGRFDEWTECAK
                     GGYSKGELTLKKETILYVYAGESGYKKFSNISDWAGFNGGGRGPNEGVDPKFTTCGGG
                     ATDIRLIGGVWNDEQGLLSRIIVAGGGGSISTSSSLIGLGGGFVGGMGVASGTTCTGG
                     TQYEGGVTVNSSGNGSFGKGGSGNVCAGGGGWFGGAGASSSAVGGGGSGYVLTKDSYK
                     PKGYIPTSEYWLENVNSIAGDNTSNAHGYAKITLLQALPFLTVSSYNSTQATFKADHT
                     DPTLLTKIEYFINDVLKETITTDLTTEKTINYTLEDNALHTLKIVVTDSNNATAEKVL
                     SISKNIMPLPEDVNLQDISSKLIEVNAGFKTGKTSIINTLALKNIEANLNNTLVELSE
                     KIKTGFDSSDATAEQLQNQITNLNNQLSQRKRWAKGTYTFTQSDYENFYSRYSSAENY
                     AKSLTVPINLNFIPSLVIVEKLCFYGNGYTVNFYAINNLNQLASVGRVPKSSGEYRFC
                     AFMFVKTITSKEFSLYTYRDEYTDSSSVVYRCKVGESFTWYAYE"
     gene            4749..5042
                     /locus_tag="KOU88_003860"
     CDS             4749..5042
                     /locus_tag="KOU88_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213675.1"
                     /translation="MERGNRIICDQTGKILLQTGEATGDILEHDEITELHFVDIPYGS
                     IDYTRNRIIGINIETKEPILEEIPTFISDEEKRIQELENQILLNENEKVGGIL"
     gene            5042..5224
                     /locus_tag="KOU88_003861"
     CDS             5042..5224
                     /locus_tag="KOU88_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213676.1"
                     /translation="MNINNVVVRILAERILNKGLNPLKNRVFELDDVTNTEYRMAVEN
                     YIIEHSEVVEGAELTK"
     gene            5265..5495
                     /locus_tag="KOU88_003862"
     CDS             5265..5495
                     /locus_tag="KOU88_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBK3213677.1"
                     /translation="MNEELVKEKISTLETRVKEHGKQIDRIEIEQAKFAIQIQNLCSD
                     IKNLTGVLKWLVGVIITTLVGFFIFAIQKGIF"
     gene            5515..5772
                     /locus_tag="KOU88_003863"
     CDS             5515..5772
                     /locus_tag="KOU88_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK3213678.1"
                     /translation="MDNLISFIPEQLLLLVVALNVLGFGFKKYKQLDNKYIPIILLVI
                     GIGFSIWMLGFNPSSILQGILCWGVAIGANQVYKQLKDGDK"
     gene            5772..>6504
                     /locus_tag="KOU88_003864"
     CDS             5772..>6504
                     /locus_tag="KOU88_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3213679.1"
                     /translation="MKIAIVPGHTLSGKGTGATGYIDEGKENRILTDLIVKWLKQGGA
                     TVYTGKVDKSNNYLAEQCEIANRQNVDVAVQIHFNADHTTLNSMGTETIYKTNNGKIY
                     ADRVNTKLATVFKNRGAKSDVRGLYWLSHTKAPAILIEVCFVDSKADTDYYIRHKDIV
                     AKLIAEGILNKNINNEGVKQMYKHTIVYDGEVDKILANVLSWGYSPSKVLVCDIKDYV
                     PGQTENLYVVGGGACEKISSITKEKF"
BASE COUNT         2555 a          736 c         1304 g         1909 t
ORIGIN      
        1 aggcaagaac caagtaagac ctttaaatta aatatagaaa aatctaagat agatggtatt
       61 tgtgatgatg tggaagcatt aaaacaaacc atctttttaa ttttaaacac agagagatac
      121 caacatctaa tatatagttg gaattatgga gtcgagttga acgaccttat tggagagcct
      181 atatcctttg taatccccga acttgaaaga cgaatcaaag aagcactaat tcaagatgat
      241 aggattgaaa atgtagataa ttttgagttt gaaaatataa aaggaaaggt caattgtaaa
      301 tttatggtcc ataccaaata tggaaatatc aaagcagaga gggtggtgag tgtttagtgt
      361 ttgaatttat gacatttgaa aatataatta aaagaatgct agatagtgta cctagcacgc
      421 ttgacaagag agaaggttct ataatatata atgctcttgc tcctgttgct atagagttat
      481 ctgaaactta tattgctatg gatgaattac tagaccaaac attcgtagat actgccagtt
      541 attactactt ggagaaacga tgtaaggaaa gaggaattac accactcgaa gcaactaata
      601 caattgcaaa aggagttttt aacatagata ttccacttga ttctaggttt aatctaggag
      661 aatataacta tgtagcaatt gagagaatat ctgaatgtat atataagatg aaatgtgaga
      721 ctgcgggacc tatttttgag ttggggcaac taatacctat cgaatatata gacaaattag
      781 aaacagcaga actgacagaa atactgataa atggagaaga tgaagaatca gaggacagtc
      841 taaggcaacg atattatgat agtttaaatt cacaatcatt tggtggaaat atgcaaaatt
      901 ataaagatga agttaacaaa atacaagatg ttggaggagt taaggtttat cctgtgtggg
      961 acggtggagg aactgttaag ttagtaataa ttaattctaa tttcaaagta ccatcagagg
     1021 atttagttaa tttagtgcaa gaagaaattg acccaattgg acatcaagga caaggcttag
     1081 gattagcacc aattggacac cgagtcacag ttgaaggagt tacaagtaca actataaata
     1141 tatcagcaga aataacatat aagagtggat atacatggga gaatataaaa acaattgcag
     1201 aagaagcagt tgatgactat ttaaatgaac ttaatatgag ttgggaagat gaagaaaact
     1261 taatagttcg tatatctcaa attgaaacta gattacttag tattgatgga gtattagaca
     1321 ttgcaaatac aatgataaat agcattgcat ctaatcttaa tgttgataaa gattctatag
     1381 tattaagagg tgaagtagtt ggataaagag attaatctaa taaattactt accgcaaatc
     1441 ctacgagata aagaagaata tataaaagta tttaatgtag aaaacaaaga aataaaaaca
     1501 ctacatgaaa aattaaatga cctatcaaat gaccagtttt tagaggattt aactccaagt
     1561 ggcataaaaa gatgggaaaa gataatgtct ataactccta aaagtaatga gagtttagaa
     1621 gatagaaggt ttaggatttt tagtaaatat ataagtaaat taccttactc agagagattt
     1681 ttaaggaact ggctagataa tgtagttgga gaaggcaatt atgagttaac tataaataat
     1741 gctacttata atatacatct tgaaagtgat gctagaaatc aagattggtt tgaggaagtt
     1801 cattcttttg taagtaatat taagccatgt aatatgactt tagattacac tagagtgctt
     1861 ataagcaaag acaattatat gaattttggt ataacaaccc taatgggtca agaaataact
     1921 atataccctt ggagtccacc agatatagaa acttatggag aaattgatgt attaactggc
     1981 aatggagttg gataccaaga gataacaata ttttaggagg tgatatattg gctatagata
     2041 aaagttatta cactataatt acagatgtag gaaaagcaaa gatagcaaat gcaagtgtca
     2101 caggtaataa agtgggattt gtaaaaattc aacttggtga tggaggaggg agtgaatata
     2161 ctccaactga gagtcagaca gctctcaaaa acgtggtatg ggaaggcaat attggaaata
     2221 caactacaga tgaaactgca ccaaattgta taatattaga gagtttaata ccatcaagtg
     2281 taggcggatt tatgataaga gaaataggat atttagatga tgaaaataat ttaattgcca
     2341 tttctaaata caaagagtgt tataaacctt ctatagaaca aggtgcagtg gtagacatga
     2401 aggttaaaac tgtgcttatt gtatctaatg taaataatat agaacttaaa attgacccaa
     2461 caataatctt tgcaacactc aaagatatac aagacttaga aactaaaata ggtactgtta
     2521 atactaaaat agatacaact aaaacagaat taacaaataa tttagaaact gctaaaacag
     2581 agttaaatac tagaattgac acagaaaatg agaaacaaaa tattaaaatt gaccaactta
     2641 ttgcaggtgg ctctaatgtg gcatctactc aaacaataac aattgacgat tgggttgagg
     2701 atgcagaaaa tggattcaaa gcaactgtaa cacatagttt attaacacag agaatagttg
     2761 taaatattat agatgctact acaaaagaaa atgtagttac aaactttaaa attatagatg
     2821 ataattctat agaagttaga agtgaaacaa ggtcagaatt aaacgtttat gtgataaatg
     2881 gaaatgcaga aactcatttt ataaatgcaa ctgtagatga taacagagtg tctgaaatga
     2941 ctacttattc gtctaagaaa attgaagata gatttcttaa tttagaagaa aaagtaaatg
     3001 gtgggatatc tagtattgca acaagtgtaa atgagttgat aacttattgt tagagaggag
     3061 agtgagaaaa tgcagactga atggaatttt gattatattg gagcagggaa aaaagttaca
     3121 ttaaaacctg gtaagtataa attagaatgt tggggtgcta gtggaggtgg tcgttttgat
     3181 gagtggactg aatgtgctaa aggtggctat tctaaaggag aactcacatt aaaaaaagaa
     3241 actatattat atgtttatgc tggtgaaagt gggtacaaaa agtttagtaa cattagcgac
     3301 tgggctggtt ttaatggagg gggaagaggt cctaatgaag gtgtagaccc taaatttaca
     3361 acatgtggag gcggagctac tgatataaga cttattggag gtgtttggaa tgatgagcaa
     3421 ggattattat cacgtataat tgtagcagga ggaggaggtt ctattagtac ttcttcttct
     3481 cttattggtt tagggggtgg atttgttggt ggtatgggtg ttgctagtgg aactacttgt
     3541 actggcggta ctcaatatga aggtggtgta actgttaata gtagtggcaa tggttcattt
     3601 ggaaaaggcg gaagtggtaa tgtttgcgct ggtggaggag gttggtttgg gggtgctggt
     3661 gcttcttcta gtgctgttgg tggtggtgga agtggttatg tgttaactaa agatagttat
     3721 aaaccaaaag gatatatacc tacatctgaa tattggttag aaaatgttaa tagtatcgca
     3781 ggtgataata ctagtaatgc tcatggttat gctaaaataa cattactaca agcattacca
     3841 tttttaacag tatcttctta taattctaca caggcaacat ttaaagcaga ccacacagac
     3901 cctacactat taactaaaat agaatatttt ataaatgatg tattaaaaga aactatcaca
     3961 acagatttaa caacagaaaa aacaattaac tatacactag aagataatgc actacacaca
     4021 cttaaaatag ttgttacaga cagtaataat gctacagcag aaaaagtgtt aagtataagt
     4081 aagaatataa tgccattgcc cgaagatgtg aatctgcaag acatatcttc taaactaatt
     4141 gaagttaatg caggatttaa aactggaaaa acaagtatta taaacacttt agcattaaaa
     4201 aatatagaag caaatttaaa taatacatta gttgaattat cagagaaaat aaaaacaggt
     4261 tttgatagtt cagatgctac tgctgaacaa cttcaaaatc agattactaa tttaaataat
     4321 cagttaagcc aacgtaaaag atgggctaag ggtacttaca cttttactca aagtgattat
     4381 gaaaattttt attcaaggta ttcaagtgct gaaaattatg ctaagagtct tactgttcct
     4441 attaatttaa atttcatccc tagtcttgtc attgttgaaa aactttgttt ttatggaaat
     4501 gggtatactg ttaattttta tgctattaat aatttaaatc aacttgcttc tgttggtcgt
     4561 gttcctaaga gtagtggaga atatcgtttt tgtgctttta tgtttgtaaa aactattact
     4621 agcaaagaat tttctttata tacttatcga gatgaataca ctgatagtag tagcgtagta
     4681 taccgttgta aagtcggaga aagttttaca tggtatgctt atgaataata tgaaaggtgg
     4741 taatttaaat ggaaagagga aatagaatta tatgtgacca aaccgggaaa atattactcc
     4801 aaactggaga agcaacaggg gatatattag aacatgatga aataacggaa ttacattttg
     4861 ttgatattcc gtatggaagt atagactata caagaaatag aattataggt ataaatatag
     4921 aaacaaaaga accaatttta gaggaaatac caacatttat ttcagatgaa gaaaagagaa
     4981 tacaagagtt agaaaatcaa attttattaa atgaaaatga gaaagtagga ggaattttat
     5041 aatgaatata aataatgttg tagtaagaat attagcagag agaatattaa ataagggatt
     5101 aaatcctcta aaaaatagag tatttgaact tgatgatgtt actaacacag agtacaggat
     5161 ggcagttgaa aactacatta tagaacatag tgaggtagta gaaggagcag aacttacaaa
     5221 ataggtaatg ttcttttttt aatacaaagc aataggaggt tttcatgaat gaagaacttg
     5281 tgaaagaaaa aataagtaca cttgaaacaa gagtaaaaga acacggcaaa caaattgata
     5341 gaatcgagat tgagcaagca aagtttgcta tacaaataca aaacctatgt agtgatataa
     5401 aaaatctgac aggagtactc aagtggcttg taggagttat aattacaact ttagtagggt
     5461 tctttatatt tgccatacag aaaggaatat tttaattaat taggaggtta agatatggat
     5521 aatttaataa gttttatacc agagcaactg cttttattag tagttgctct taatgtatta
     5581 ggatttggat ttaagaaata caaacagtta gataataaat acattccaat catattgctt
     5641 gtgataggaa ttggattttc aatatggatg ttaggattta atccttcatc aattttacaa
     5701 ggaattttat gttggggagt tgcaataggg gcaaatcaag tttacaaaca gttgaaggat
     5761 ggtgataaat aatgaaaata gcaatagtac caggacacac tttaagtgga aaaggaacag
     5821 gagcaactgg gtatatagat gaaggaaaag aaaacagaat cctaactgat ttaatagtaa
     5881 aatggttgaa acaaggtgga gctactgtat atactggaaa agtagataag tctaataact
     5941 atttagcaga acaatgtgaa attgccaata ggcaaaatgt agatgtagct gtacaaatac
     6001 attttaacgc tgaccataca acattaaatt ctatgggtac agagacaatt tacaaaacta
     6061 ataacgggaa aatatacgca gatagggtaa atactaaatt agcaactgta tttaaaaaca
     6121 gaggtgcaaa atcagatgtc agagggcttt actggcttag tcatacaaaa gctccagcga
     6181 tattaataga agtgtgcttc gtagatagca aagcagatac agattattat attagacata
     6241 aagacatagt tgctaagtta atagcagaag gtattttaaa taaaaatata aataatgagg
     6301 gagttaaaca gatgtacaaa catacaattg tttatgatgg agaagttgat aagatacttg
     6361 cgaatgtgct tagttggggc tatagtccaa gcaaagtttt agtttgtgat ataaaagatt
     6421 acgtaccagg tcagacggaa aatttatatg ttgtaggagg tggcgcatgt gaaaagataa
     6481 gttctattac taaagaaaaa ttta
//
LOCUS       DAFAZV010000098         6309 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFAZV010000098 DAFAZV010000000
VERSION     DAFAZV010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6309
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.101"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(170..370)
                     /locus_tag="KOU88_003865"
     CDS             complement(170..370)
                     /locus_tag="KOU88_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213680.1"
                     /translation="MPKFTCNLKKYRQLKELTQEQLAEKVGVRRETIMRLEAGKYNPS
                     LKLAIDISKIVDTPIDELFIFD"
     gene            complement(372..722)
                     /locus_tag="KOU88_003866"
     CDS             complement(372..722)
                     /locus_tag="KOU88_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3796 domain-containing protein"
                     /protein_id="HBK3213681.1"
                     /translation="MIQKKFFMGFCGFLGFLSLRYFSSGNVADLTYIGFFAFFSNFII
                     AKINGDKADERYVQDEKAAMAFTGQLAIIELFILWCITIVSRNIELMCVLLSITYAIT
                     LNVYAIKLYILEEK"
     gene            884..1073
                     /locus_tag="KOU88_003867"
                     /pseudo
     CDS             884..1073
                     /locus_tag="KOU88_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890498.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1550..1720)
                     /locus_tag="KOU88_003868"
     CDS             complement(1550..1720)
                     /locus_tag="KOU88_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213682.1"
                     /translation="MHVYQPKTSEYLLNTYAKSYLSSIVFLFDYITKNESGYAFFIID
                     FPFLSLDIFYKF"
     gene            complement(2109..2603)
                     /locus_tag="KOU88_003869"
     CDS             complement(2109..2603)
                     /locus_tag="KOU88_003869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBK3213683.1"
                     /translation="MKNKKGFTLVELLVVIAIIGILAIVALPALFKNIEKAKIAKLEA
                     DISAIKSASLSYYADESKYTDGGMISWVKKDGKIIINGGFKDDPLADKIENLGMPYNG
                     SYLLMSSPGHEKYLELSILPEGEISKSGLDKLKSDYGSSIDIMNEQNKIDIVIKFLND
                     KSNT"
     gene            3408..3785
                     /locus_tag="KOU88_003870"
     CDS             3408..3785
                     /locus_tag="KOU88_003870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213684.1"
                     /translation="MKEEILIEKLLRVELIVMEYLWKKDTLMPKKKIVKEIKQIYGWH
                     KSTIKILLKRLVDKRYLARYIINFQSYYKIIIDNKEYYTFKKKVLKSSKSIKIMHSLT
                     TIHKNVSKEKLDLLDEYYRNLKE"
     gene            3890..4265
                     /locus_tag="KOU88_003871"
                     /pseudo
     CDS             3890..4265
                     /locus_tag="KOU88_003871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003430377.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
     gene            4555..5073
                     /locus_tag="KOU88_003872"
                     /pseudo
     CDS             4555..5073
                     /locus_tag="KOU88_003872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            5513..5767
                     /locus_tag="KOU88_003873"
     CDS             5513..5767
                     /locus_tag="KOU88_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213685.1"
                     /translation="MENKDIKLTICIFAFVIGIIVLFCCIGLGQFNMDCIIKQNGGSI
                     ATEQYNIYLEQSISQYRNFGSILVLLGGIGILFDKSVRKY"
     gene            5803..6126
                     /locus_tag="KOU88_003874"
     CDS             5803..6126
                     /locus_tag="KOU88_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213686.1"
                     /translation="MARDVFSVKMTPLEAQKMVEKNLEADLVSVDIYNLENNKSIIVT
                     IFEKYYARSNSDAGLVVICENTTGKTLVKITSTGSAIGLSQIDWGTGNNLIKRVKKIL
                     IDYII"
BASE COUNT         2633 a          671 c          855 g         2150 t
ORIGIN      
        1 attaataata caatagaatt agttattatt caacatatct agctgaaaaa ttaataaatt
       61 tatatatgaa cgttaaatta tctgaaaaaa taaaaagccc ctctgtcagg agtgacttaa
      121 aaattgaatt taagtttgta tttaaaacac atttttaata atgcaaaaac taatcaaaaa
      181 taaacaattc atcaataggt gtatctacta tttttgatat atctattgct aatttcaaag
      241 aaggattata ctttcctgct tctaaacgca taatggtttc tcttctaact cctacttttt
      301 ctgctaattg ttcttgagtt aattctttta attgtctata tttttttagg ttacaagtga
      361 atttaggcat attatttttc ctctaaaata taaagtttta tagcataaac atttaaagtg
      421 attgcatatg taattgatag taaaacacac attaattcta tattcctaga cactatagta
      481 atacaccata aaatgaataa ttctataata gcaagctgtc ctgtaaatgc catagctgct
      541 ttttcatctt gtacatacct ttcatctgct ttatcaccat ttatttttgc tataataaag
      601 tttgagaaaa aagcaaaaaa tccaatatat gtaaggtcag caacattgcc agatgaaaaa
      661 tatctaagac ttaaaaatcc aaggaaacca caaaaaccca taaaaaattt tttctgaatc
      721 attttttatc ctccttagta attttaaaag agatatattt atatctttat gatacaaata
      781 tatctctttt atattctttt gtcaatagaa aatcagtatt atacaatatt tgtactgcac
      841 cataattgtt agagcaaaaa tctactgctt gagatgttta tgtatgacta aatatgattt
      901 taatttcaaa ttaaaagtag ctaaatttta tttgaataga gaaggaagag atattttaat
      961 agtaaaacaa tatggagttt ataaccattc tcaagttgaa agatgggtta atatattagg
     1021 agagtgtgca ctaaaaataa aaaaaatttt ctatactata tggttcaagt tagatgttat
     1081 aaactatatg atgataacta aatatagtgt acaataaatc gctaagtatt ttggaataaa
     1141 caatagcaca gttatagcaa catgaaaata aaaattttta catagtggtg ttgatgcctt
     1201 ttctaaaatg aaaggaagac cataatgaat aaaaacaaaa acactaaaga aaaaataaat
     1261 taacaagaga acaagaatta gaatatgaaa ataaattttt aaaagatgag cttgagtttt
     1321 taaaaaagat gtgtgcctca gggaagccac attaaaaaac agtggtatca ttattaatca
     1381 aaagaaagtt agatgtatta tcaaaaaatt agaacttaaa tgcatagcat tttttcataa
     1441 atcacataaa tataactcct ataaatgtat aattggaaaa gtaaaaaata ataaaacaaa
     1501 tagaagattt aaaatatcaa tagcatatca gaaaataaca aatgatatgc tagaatttat
     1561 aaaatatatc taatgataaa aatggaaaat caattataaa aaaggcatat cccgattcat
     1621 tttttgttat atagtcaaat aagaatacta tagatgaaag atacgatttt gcatatgtat
     1681 taagtaagta ttctgatgtt tttggttgat acacatgcaa taaagaagtt gtgtttgcag
     1741 ataaattagc aaaactatag tataagttgc aacaataaag aaaatgaaaa ttatcatact
     1801 aaagcataag gcatgttaca attttattag ataggacatt aacatacatt aaagtacttt
     1861 ttattataaa gagtacttat ttttttgaaa ttcattaatg tataaactat caagaatatt
     1921 actcaacata atttaaaaac aacttgaata ggtattttta aattatgtga tataataaaa
     1981 aatagaagtg tatgccaata cacttctgta attataacta agcattctat tcttgaggag
     2041 tgcttttttc atttctccaa acaagattgt ttatttcatc agcaattatt aaataaaatt
     2101 tattgtattt aagtattcga tttatcattt aaaaatttta ttacaatatc tattttgttt
     2161 tgctcgttca ttatgtctat tgaacttcca taatcacttt ttaatttatc tagaccactt
     2221 ttgcttattt ctccttctgg aagtatactt aattctagat atttttcatg accaggagat
     2281 gacattaata gatatgaacc attataaggc atacctaaat tttctatttt atctgctaat
     2341 gggtcatctt taaagccacc atttattatt atttttccat ctttctttac ccatgatatc
     2401 attcctccat cagtatattt tgattcatct gcatagtagc taagagacgc actttttatt
     2461 gcacttatat cagcttcaag tttagctatc tttgcttttt ctatattttt aaataatgct
     2521 ggaagtgcta ctattgccaa tattcctatt atagcaatta ctactaataa ttccactaga
     2581 gtaaatcctt ttttattttt catttatttc ccctccatat aaaattaata atatataaat
     2641 ttttattttg ttgatttcta ctttctatat tttaccatat atagacaaaa aaatcacttt
     2701 ctatgacaaa tatactatta ttttacaatt tatggaaatg atttaaaatg acatttcttg
     2761 ttagaaaaga tataagaaat ggattaaaat aaagaaaact acagtcatat caatgtcaat
     2821 aatattattt aaaagcagat gaaaataaaa agaggactca gaaaataatg tctatttaat
     2881 tatacttact taccaatacc ataacttgat ataaacaaga ttatactaca ttttttttat
     2941 gctctagtat aaaatcatct aactgtgtat ctataaaatc aaaataatta tatgaactat
     3001 cagtataata agtcaaaata tgtatacatg aatacatatt ttaaaagata tatattatta
     3061 catacctaaa aaactttcat aaaaacaaaa ataaaatatg cttttagtaa cttgttaaca
     3121 taacttataa tttattttat aggcattagc ctatatagct ttgtgctact aaatttcttt
     3181 gattctagcg atttagtgct attctacaac taaaataata caatagagct atttattgtt
     3241 tggtagcatt gtttgcaaat taaacaaatt tatatatatg aatattattt tacgtttaaa
     3301 aaaacagact aaatatgtag aatatttggt aaaacttacc tctagttttt gtcttaaaaa
     3361 gctcctatta ttaatttaag ttagaaaaat taaggaagtg acataaattg aaagaagaaa
     3421 tattaataga aaaattatta agagtagaat taatagtaat ggagtattta tggaaaaaag
     3481 acactctaat gcctaaaaaa aaaattgtaa aagaaataaa acagatttat ggatggcata
     3541 aaagtacaat aaaaatacta ctaaaaaggc tagttgataa aaggtatttg gctagatata
     3601 ttataaattt tcaatcttat tataaaataa taatagataa taaagaatat tatactttta
     3661 agaaaaaggt actaaaatct agtaaaagca taaaaataat gcattcactt accactatac
     3721 ataaaaatgt aagtaaagag aagttagacc tattagatga gtattataga aacttaaaag
     3781 aatgatatag taaaaatcga atgtaattat ttaccttaat tcctttgttt gtaaaacttt
     3841 attgatatag aatttgacat atacataaat tggtaaaggg atgtatacta tgaaaattag
     3901 taaattacca gaagcggaat taaaagttat gagatatatt tgggaatcag aaaaggtatt
     3961 aatatcaaga gaaatcacca agtctatgga acaaaaatat gaatggaaag atacaactat
     4021 atttacagta ttaaaaagat taataaagaa gagagttttt agaaacggag aaaatagata
     4081 agtgtacaca ctataatgta ttagtaaaag aaaaataata tcagagattt taaacaaaag
     4141 aatttttaaa gaatacacat aaaaattcaa tattaagttt aatgtcagcg ctatgtagta
     4201 aggatgatga agtagatggt gatattttaa atttattaga agaatatttt aagaatttga
     4261 aataagaaaa tgacaaattg atacataata aataaaaaga aggtatgaaa ttataacttt
     4321 ttctaccttc attttgttta ttattctgaa catgttaaga aaatgaaata ggtttgtcta
     4381 atatttatat aaattttagt agaatatgta tagtatatag tagatagtat gtataaaaat
     4441 aaaaactgtt caataagaat taatatacat taattcagct gaatccaatc aaaatactta
     4501 aataaaagta atctgaaaat aacataattc aaatcaattt attcaaataa acctcaattt
     4561 atctaaaatc ttaagaagtc attaaacaaa cttgctaaat tacaaagaga attatcgaga
     4621 aaaacaatcg gtagtttaaa tagaaataaa gcaagattaa aagttgcaag acttcaagaa
     4681 catatagcta atcaaagaaa tgattttcta caaaaactat ctactaaatt aataaaagag
     4741 aacgatatta tttgcataga agatttacaa gtaaagaata tgattaggaa tcttaaacta
     4801 tctcgctcaa tttctgatgt gtcatggtca gagtttattc gtcaattaga atacaaggct
     4861 aattggcatg gtagacaaat tgtaaaggtg ggtaaattct ttgcaagttc acaaatatgc
     4921 aataaatgtg ggtataaaaa cgaggaagtg aaggacttaa atataagaga atggatttat
     4981 cctagttgta atgaaactca cgatagagat ataaatgcaa gtataaatat attaaaagaa
     5041 ggattaagac taataacaat tcaaaataaa taacgtatgt aagaaccgta ggaactacgg
     5101 ggatagcctg tggagaatta gtaagacata tgttagtatg caaaattctg tgaagcagga
     5161 aatctgtgac tttagtcatg ggaggttcag gctagtatta ctcattattg tattcaaaag
     5221 ctaaagtgga aacctagtga atatatgaat ttagaagtta atgagagagc attagcagcc
     5281 gactcaatac ttattaaaat tgaagatgaa gaagaagcaa tgaaagaaga tgaaagagag
     5341 aaaaagagag gtagaagaag gtagaattta aagttaaaat agtcacattg ctaatatatg
     5401 aaaatgttac aattttggaa atagatggat atatatgttg tatagtataa tgtagataat
     5461 atatcaccaa gtaaaaaaca acaaataaat ctaaattatg aggggtgtat ttatggaaaa
     5521 taaagatatt aaacttacaa tatgtatatt tgcttttgta attggaataa tagtgttatt
     5581 ttgctgtata ggtctaggtc aatttaatat ggattgtatt ataaaacaaa atggtgggtc
     5641 aatagctacc gaacaataca acatatattt agaacaatct atttcacaat atagaaattt
     5701 tggttctata ctggttttac taggaggaat aggaatactg tttgataaaa gtgtcagaaa
     5761 atactaaaaa agtatatttt tatttaggat gtgatgaatg atatggcaag agatgtattt
     5821 agtgtaaaga tgacaccact agaagcacag aaaatggtag aaaaaaattt ggaagcagat
     5881 ttagtttctg ttgatattta taacctagaa aataataagt ctataatagt tacaatcttt
     5941 gaaaaatatt atgcaagaag caatagtgat gcaggtttgg tagtgatttg tgaaaatact
     6001 acaggaaaaa cacttgttaa aattacctca actggtagtg caattggact atctcagatt
     6061 gattggggaa caggtaataa tttgattaaa agagtaaaaa aaatacttat tgattatatt
     6121 atttaattat tttatgtaga tattcttagg ttggtatgga atttgtacta acctattaag
     6181 taatcaataa aactaaataa acatagaaag cacttacaaa tatgtaggtg ctttttattg
     6241 aaaaaataga aaataaaata aaaagtaaga tataggaaaa atatgtaaga attatatatt
     6301 ataataatt
//
LOCUS       DAFAZV010000099         6253 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFAZV010000099 DAFAZV010000000
VERSION     DAFAZV010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 6253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6253
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.102"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..445
                     /locus_tag="KOU88_003875"
     CDS             <1..445
                     /locus_tag="KOU88_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HBK3213687.1"
                     /translation="IVLSLSLVGCSTNDSKNGDSKPKQNTEEIKNHKIGEVVDLDGAK
                     VSVKNVRKLESDSNVYAVEIEITNTGDTDLESDFLQNYILKTDDNTVGNAINNQELNG
                     ELLFDTIHPGDTLKGEIAFELTKDTKPKTIEIAYENVGKYTVFDL"
     gene            503..1138
                     /locus_tag="KOU88_003876"
     CDS             503..1138
                     /locus_tag="KOU88_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK3213688.1"
                     /translation="MEIWLRQANNTFRFPVIPPSFEINGSATINTSNILSVGDIAVFG
                     GLGLKTIELSSFFPNQEYSFCNYNGFPKPYDCVNLIESWMKEGYILRFIITETNINFE
                     CIIADFNYREQDYSRDVYFTLSLKEYRRIQISKVNINNDEKLSSEKDVPLTKGFDTKQ
                     KTHKVVEGDTLFKIAKKYYGNGDLWEKIYKANEDKIKDPSVIKNGWILIIP"
     gene            1378..2895
                     /locus_tag="KOU88_003877"
     CDS             1378..2895
                     /locus_tag="KOU88_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003419653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK3213689.1"
                     /translation="MIIDRSKDSSNNNIDFTAKDMGFLLLQSEVSYNFKDKLVEDIAK
                     QVFVDNKFPLGNLPKTNVKYTKMFIGVTGYDTIMSVYTEASKTTKKKYMIESNLDKFN
                     VIEKGVVTLNITFEEGFNLINTNFSESMENVKNKVLVVDQYGNKISEKINDSIFKDVG
                     VIMQKVIQQQENSTIDIDGEFKGIEKTCSLKGYGDITCVTGRGVKVKDSYTKLIGLFY
                     IDTDKHTWQNGDYQIELELNFENIMDEKSAGQDEQKEDGSEYTGGTEYSAEFTAYCPR
                     KSEGGDKDCRGKKLDPSKKTCAAPMVGTYEKSYYTKDFLNKHPLMRYGDEIQLVTGVS
                     SRDGTYKVNDNGPAIIIEKDGTYHIDILFGNVEEANNFGRRKGKIIIGGYSGNVTEKA
                     KTVISEARKHLGKPYKWGGNGPSSFDCSGLMVYCFKKVNVNLPRTSSQQSKVGKKVEK
                     NNLQAGDLVFFHNPVSHVGLYVGNGEFLHAPQTGDVVKISKLSNRKDFNTARRVL"
     gene            2909..3241
                     /locus_tag="KOU88_003878"
     CDS             2909..3241
                     /locus_tag="KOU88_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 family protein"
                     /protein_id="HBK3213690.1"
                     /translation="MADPINEFIGIMRQEGKFHNEPSFFIGKIKSKLPDLKIEINNII
                     LEKEDILIDSWMLDRQIELFDTETSQEHKHEIKNPFIDTFESGDTVIMFKIGEKFAVV
                     SKLVSLDE"
     gene            3234..3668
                     /locus_tag="KOU88_003879"
     CDS             3234..3668
                     /locus_tag="KOU88_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2634 domain-containing protein"
                     /protein_id="HBK3213691.1"
                     /translation="MNNTIFPFMGVPEDYISPTNEELPIFKEFAWDFNKDEKIIENGD
                     FKIVERNEAIKVWIYKTIKTDKYVHLIYDWDYGTDIKNLIGQKYTKGLTESEAKRYIQ
                     ETLLTNPYILEVNVTNTKFKDDNLSISLNVKTIYGEEEITFA"
     gene            3661..4713
                     /locus_tag="KOU88_003880"
     CDS             3661..4713
                     /locus_tag="KOU88_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBK3213692.1"
                     /translation="MHNGQSFSVLNNRTLNNINLPLYKGQGSSLYNIVSPINSELAQL
                     YIELSYIHKRVFIQDNFDDFLDRRVNEFGVYRKLGTEAIGEVIFEGKIGTKIPNGTII
                     SYSDLLFVVIKDITIDEDSKLNVSPIQALEVGIKYNLSAKTEFKLIEEINGVTKIYNE
                     LDIKGGTEIETDEELKERFYKIQKNQATSGNKAHYQSWALEVEGVYNAKVIPRWDGPG
                     TIKILIYGQNNQSVDNEVLQRCTEHIEEEKPIGPTITIVTPSTFDITISATLTLENGY
                     DIESIKVMFLDIINSYLIENSKEIIYIKIMSLLASIEGVHDIKNLLVNDDVKNIIVDE
                     EKVPAVSSAIFDIEVS"
     gene            4715..5332
                     /locus_tag="KOU88_003881"
     CDS             4715..5332
                     /locus_tag="KOU88_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2313 domain-containing protein"
                     /protein_id="HBK3213693.1"
                     /translation="MKLIDYLPSFANNEIDIQIQEALENELLTLIDEKDDLLDQFFID
                     TATWGLDDWESLLDIKINYKLDFDTRRSNIKAKLRGKGTTTIEVIKAISEAYTKTNVD
                     VKVFSNLFSFTLSFLTNDCSYNTILELDKKIEEIKPCHLEHKFEMILFNKNNMFTGST
                     MNTGETVTIYPYSTTDITSFGELTITTGNDRSMEKVTLYPRQEVV"
     gene            5334..6158
                     /locus_tag="KOU88_003882"
     CDS             5334..6158
                     /locus_tag="KOU88_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3213694.1"
                     /translation="MAEQKYYTLLTTIGKASIANATALGNKVDLVKLQLGDGAGAEYN
                     PTEEQTSLKNVVWEGSINNVKIDEENPNWIVIETVIPGSVGGFMIREVGIFDSKEQLI
                     AVSKYPETYKPTADSGSVKDLVIKIILVVSNTSSVNLKVDPTVILATLKDIQDLDSKI
                     DTTKTELTSNIETAKTELNTKIGDTTQLTTTDKTNIVNALNEVKTSVDSIETTAEKTS
                     IKDIDNLFESDNVEGALNQLAINYNILLEKQDNLETEVNGQRIKGISIANSLIDMI"
BASE COUNT         2591 a          672 c         1128 g         1862 t
ORIGIN      
        1 aattgtatta tctttaagtt tagttggatg cagcacaaat gattcaaaaa atggagatag
       61 taaacctaag caaaatacag aggaaattaa aaatcataaa ataggcgaag ttgttgattt
      121 ggacggagca aaggtatctg ttaaaaatgt tagaaaacta gaatcagata gtaatgtata
      181 tgcagttgag attgaaatca ccaatacagg agatacagat cttgaaagtg atttccttca
      241 aaactacata ctaaaaacgg atgataatac agttggaaat gcaataaata atcaagaatt
      301 aaatggagaa ttactatttg acacaataca tccaggagat acattaaaag gtgagatagc
      361 atttgaactt acaaaagata caaagccaaa aacaattgaa attgcttatg aaaatgtagg
      421 aaaatataca gtatttgatt tataataatt atcttaaaag acacttattg aaataagtgt
      481 cttttatttt aggaggagtt taatggaaat atggttaaga caagcaaata atacatttag
      541 gtttcctgtt attccaccct cttttgagat aaatggaagt gcaacaataa atacatctaa
      601 tattttaagt gttggagata ttgcagtatt tggagggtta gggcttaaaa ctatagaact
      661 atcctctttt ttccctaatc aagaatatag tttctgtaat tataatggat ttccaaaacc
      721 atatgattgt gtaaatttaa tagaaagttg gatgaaagaa ggatatatat taagatttat
      781 cattacagaa actaatataa actttgaatg tataattgca gattttaatt atagagaaca
      841 agattattca agagatgttt attttacctt aagtctaaaa gaatatagga ggatacaaat
      901 atccaaagta aacattaata atgatgaaaa attatcttct gaaaaggatg ttccactaac
      961 aaaaggattt gatactaagc aaaaaacaca taaggttgtt gaaggagata ccctttttaa
     1021 gatagcaaaa aaatattatg gcaatggaga tttgtgggag aagatttata aagcaaatga
     1081 agataagatt aaagatccat ctgtaataaa aaatggttgg atattaataa ttccttaaaa
     1141 tggtggtgat ttataattaa taaaatcaaa atacaagttc atataaaaaa cggaaatata
     1201 tataatgtaa ctgatttagt ggataagtgt acttggtctg gtgattatag atcaccatca
     1261 agaactttag aattttctat aattcaatct gcaagtgata ttaattttag gcagatagat
     1321 attccagtag caagtacagt ttgtttctat gttgatgata aagaactttt tagaggaatg
     1381 ataatagata gatctaaaga ctctagcaat aataatatag attttacagc taaagatatg
     1441 ggctttttac ttttacaaag cgaagtgtca tacaatttta aagataaatt agttgaagat
     1501 attgcaaagc aggtttttgt agataataaa ttcccactag gtaatttacc taaaactaac
     1561 gttaaatata caaaaatgtt tattggtgta actggctatg atactataat gagcgtttat
     1621 acagaagcaa gcaagacaac taaaaaaaag tatatgatag agtctaatct tgataaattt
     1681 aatgttattg agaagggtgt agttacttta aatataacat ttgaagaagg ctttaatctt
     1741 atcaatacaa atttttctga aagcatggag aatgtaaaaa ataaagtact agttgttgat
     1801 cagtatggta ataaaattag tgagaaaata aatgactcta tatttaaaga cgttggggta
     1861 attatgcaaa aggtaataca acaacaagaa aacagtacta tagacataga tggagagttt
     1921 aaaggaatcg aaaaaacttg ctctttaaaa ggatatggtg atataacttg tgtaactggt
     1981 agaggtgtaa aagtaaaaga ctcatataca aaattaatag gtctttttta tatagataca
     2041 gataagcata catggcaaaa tggagattat caaattgaac tagagcttaa ttttgagaat
     2101 ataatggatg aaaaatctgc tggtcaagat gaacaaaaag aagatggttc agagtatact
     2161 ggaggaacag aatactctgc tgaatttact gcttattgtc ctagaaaatc tgagggtgga
     2221 gataaagatt gtagaggtaa aaaactagat ccttctaaaa aaacatgtgc tgctcctatg
     2281 gttggaacat atgaaaaatc ttactataca aaagatttct taaacaaaca tcctcttatg
     2341 agatatggag atgaaataca attggttaca ggtgtttcaa gtcgagatgg aacgtataag
     2401 gtaaatgata atgggcctgc aataattata gaaaaggatg gaacatatca tatagatatt
     2461 ttatttggaa atgttgaaga agccaataac tttggaagaa gaaaagggaa gattataatt
     2521 ggtggttatt ctggaaacgt gacagaaaaa gcaaaaacag taatttcaga agcaagaaaa
     2581 catcttggaa agccatacaa atggggtggg aatggaccaa gtagctttga ttgttctgga
     2641 ctaatggtat attgctttaa gaaggttaat gttaatttac caagaacctc aagtcagcaa
     2701 tctaaggtag gtaagaaagt agagaaaaat aatttacagg caggagattt ggtatttttc
     2761 cataatccag tcagccatgt tggactatat gtaggtaatg gagaattttt acatgcgcca
     2821 caaacaggag atgtagtcaa aataagtaaa ttaagtaata gaaaagattt taatacagct
     2881 agaagagttt tgtaaaagag gtgatatcgt ggcagatcca atcaatgaat ttataggaat
     2941 aatgagacaa gaaggtaaat ttcataatga accttctttt tttattggaa aaattaaaag
     3001 taaattacca gatttaaaaa tagagataaa taacatcata ttagaaaaag aagatatctt
     3061 gatagacagt tggatgcttg atagacagat agagttattt gatacagaaa caagtcaaga
     3121 acataaacat gaaataaaaa atccctttat agatactttt gaatctggag acacagtaat
     3181 aatgtttaaa ataggtgaaa aatttgctgt tgtaagtaaa ttggtgagtc tagatgaata
     3241 atactatatt ccctttcatg ggtgttccag aagattatat ttctccaacc aatgaagaat
     3301 tacctatttt taaagaattt gcttgggatt ttaataaaga tgaaaagata attgaaaatg
     3361 gagactttaa aatagttgaa agaaatgaag caattaaagt atggatttac aaaacaataa
     3421 aaacagataa gtatgttcat ttaatatatg attgggatta tggaacagat ataaaaaatc
     3481 taatagggca aaagtatact aaaggtctta ctgaaagtga ggcaaaaagg tatatacaag
     3541 aaaccctatt aactaatcca tatatattag aagtcaatgt aacaaataca aaatttaaag
     3601 atgataattt atctataagt ttaaatgtaa aaacaattta tggagaggag gagattactt
     3661 ttgcataatg gtcaatcatt tagtgtctta aataatagaa ctttaaataa cataaatcta
     3721 cctctttata aaggtcaagg atcttctctt tataatatag tctctccaat aaattcagaa
     3781 cttgcacagt tatatataga actttcttat atacataaga gagtttttat tcaagataat
     3841 tttgatgatt ttcttgatag aagagttaat gaatttggag tatacagaaa gttaggcaca
     3901 gaggcaatag gtgaggtaat atttgaggga aaaataggaa ctaaaatacc aaatggaaca
     3961 ataatatctt atagtgattt attatttgta gttattaaag atattacgat agatgaagat
     4021 agtaagttaa atgtaagtcc tatacaggct ttagaggttg gtattaagta taatttatca
     4081 gctaagacag aatttaaact tatagaagaa ataaatggag taactaaaat ttataatgaa
     4141 ctagacataa agggtggaac agaaatagaa actgatgaag aattaaaaga gaggttctat
     4201 aaaatacaaa aaaatcaagc aacaagcggg aataaagcac attatcagtc ttgggcctta
     4261 gaggttgaag gtgtttataa tgcaaaagta attcctcgct gggatggacc aggtacaatt
     4321 aaaatcctaa tttatggtca aaacaatcaa tcagttgaca atgaagtatt acaaagatgc
     4381 actgaacata tagaagagga aaaacctatt ggtcctacta ttacaattgt tacaccaagt
     4441 acttttgata ttaccattag tgcaacttta acacttgaaa atggatatga tattgaatct
     4501 ataaaggtta tgtttttgga tattataaat tcttatttaa tagaaaattc aaaagagatt
     4561 atttatataa aaataatgag tttgttagca agcatagaag gtgttcacga tataaaaaat
     4621 ctccttgtaa atgatgatgt taaaaacata atagttgatg aagaaaaagt tcctgctgtt
     4681 tcaagtgcta tatttgatat cgaggtgagt taaattgaag ttaattgatt acctgccaag
     4741 ttttgcaaat aatgaaattg acatacaaat ccaggaagca cttgaaaatg aacttctaac
     4801 attaattgac gaaaaagatg atttattaga tcagtttttt atagatacag caacttgggg
     4861 gcttgatgat tgggaaagtc tcttagatat aaaaataaat tataagttgg attttgatac
     4921 tagaagaagt aatataaaag ctaaattaag aggcaagggc acaactacaa tagaagttat
     4981 aaaagctata tcagaagctt atacaaagac taatgttgat gtaaaagtgt tcagtaatct
     5041 atttagtttt acacttagtt ttttaacaaa tgattgtagt tataacacta ttttagagtt
     5101 agataagaaa atagaggaaa taaaaccttg tcatttagag cataaatttg aaatgatttt
     5161 attcaataaa aataacatgt ttacaggttc tacaatgaat acaggtgaaa cagttactat
     5221 atatccttac agtacaactg atataacttc ttttggagaa ttgactataa ctacaggtaa
     5281 tgacagaagt atggaaaaag taacattata tcctagacag gaggtggtat aggttggcag
     5341 aacaaaaata ttatacactt ttgacaacga taggaaaagc atctattgca aatgcaacag
     5401 ctttaggcaa taaagtagat ttagttaaat tacagcttgg cgacggagca ggggcagaat
     5461 ataatccaac agaagaacaa acttctctaa aaaacgtagt ttgggaaggt tctataaata
     5521 atgtaaagat agacgaagaa aatccaaact ggatagtaat agaaactgta atcccgggta
     5581 gtgtgggtgg ctttatgata agagaagtag ggatatttga ttcaaaagaa caactaattg
     5641 cagtatctaa atatccagaa acgtacaaac caacagctga cagcggaagt gtaaaagact
     5701 tagttataaa aattatttta gtagtctcta atacttcaag tgtaaatttg aaagtagacc
     5761 caactgttat tttagcaaca cttaaagaca tacaagattt agactctaaa attgatacaa
     5821 ctaaaacaga attaacaagc aacatagaaa ctgctaaaac agagttgaat acaaaaatag
     5881 gagatacaac acaacttact acaacagata aaacaaatat agttaatgca ttaaatgagg
     5941 taaaaactag tgtagatagc atagaaacaa cagcagagaa aacaagtata aaagatatag
     6001 ataacttatt tgaaagcgac aatgtagagg gagcattaaa tcaattagca ataaattata
     6061 atatattatt ggaaaaacag gataatttag aaacagaagt gaatggacag agaataaaag
     6121 gaatttcaat agcaaatagt ttgatagaca tgatataaga gaggtgagaa tatgacagaa
     6181 aagttgactg ataatgctag tttaagagaa cttatgatag catttgaaag tgcaaaaaat
     6241 gatttgcaga tag
//
LOCUS       DAFAZV010000100         5714 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFAZV010000100 DAFAZV010000000
VERSION     DAFAZV010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5714)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5714)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5714
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.103"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            26..562
                     /locus_tag="KOU88_003883"
     CDS             26..562
                     /locus_tag="KOU88_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HBK3213695.1"
                     /translation="MKKTLIIVGVVISILIMFACLFLVTKNKAIDLEEQVQSATASVE
                     VQEKRRIDLIKNIVDCVKDYAKYENRTLKEVTDMRVSANDESIKEAKLNIQAVAEKYP
                     DLKANENYKQLMSELSITENMIAQHRENYNMQVRNYNKYIRKFPANLILNSMGYEKIE
                     SKYTEYKAKEDAPQNLFD"
     gene            574..1380
                     /locus_tag="KOU88_003884"
     CDS             574..1380
                     /locus_tag="KOU88_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213696.1"
                     /translation="MKFKTFEITKREFLVSIIIACMMIVLGFFIDDKVQSKFLEDNER
                     YYKATKINNDKDLFDYAMETSAGDSLISGRFKSVDSVSIEELKGDYWFIERTEEKYTM
                     HTRVVTTKDSKGHSHKYTETYWTWDYHDSIEKKCNKFNFMGKEFDAKVITNLSKERLA
                     LKKDIFKNNNLKIKGNYAYINNKRRYYYEVIPKEFNGTMYANLKNNTIANPADKNIKV
                     FKGESIQNVLENNNFNTGFFKVVFWIIWILITTIIIYVFYYLKNDWLEDK"
     gene            1405..1665
                     /locus_tag="KOU88_003885"
     CDS             1405..1665
                     /locus_tag="KOU88_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213697.1"
                     /translation="MKCKVYHAIKNIKDANELIDRFETENIFFELNNIDNENVLNGEM
                     DLTDIEDIASLQFILDGDLFIFSSCDEMIFMNKYTQRELGLQ"
     gene            1666..2307
                     /locus_tag="KOU88_003886"
     CDS             1666..2307
                     /locus_tag="KOU88_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBK3213698.1"
                     /translation="MNKRIVCQDTNEIVYNYKEYQKTKHWESLKNEFYFSNECKCVLC
                     DSVKKVSLHHKTYRRIGAEELDDLIPLCNSCHYKVHRNNKQYLFNKATEKQIRCINDL
                     LEVYVDIVEELFMNEYIYLYVAMGIEFYNENLMLFEANHIINDLKFVSAMLYEFYATK
                     LEIKLPGYFNGFDYEEIKDSLYKKMQRLSKYIYVPKKQEIELLFKKRKKEHYE"
     gene            2362..2847
                     /locus_tag="KOU88_003887"
     CDS             2362..2847
                     /locus_tag="KOU88_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213699.1"
                     /translation="MDLKLISSIPNWKVEDQLAKIDEEVTEFKNAIDTGITKDIIAEG
                     LDVCQTILTMFQVLEIENYITEGVETHNKKLNGRGWDLKEIGDDILNLIKNSMINELI
                     NMNKKLKCLDEKEFNAKIQFLDVDKLWNLCMPLVNLSTIKGVNESIDEMKMGEFLKNI
                     N"
     gene            2867..3124
                     /locus_tag="KOU88_003888"
     CDS             2867..3124
                     /locus_tag="KOU88_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213700.1"
                     /translation="MLIEVTENNRELKVGDIVEINGGNKLYMILSLKETIGGYVIINM
                     QNGYGSFGAYKSLSQLELDLKVRGYKLYSSDDYKLQLVPRE"
     gene            3233..3676
                     /locus_tag="KOU88_003889"
     CDS             3233..3676
                     /locus_tag="KOU88_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase subunit sigma"
                     /protein_id="HBK3213701.1"
                     /translation="MQSSKKDNLFSSAEGKLYNYKKIKAEIEKIDIDMQMIKNDYRGC
                     SGVEIKEKTSKTYDIKSVIEIETEEKEKKIALKEKEKRHKELIIEKIDNAMKILSEEE
                     KKIVQYKYFSSSRTSWEYVGRMIGFSASKCKQMRFDIIDKIKGLL"
     gene            3819..4364
                     /locus_tag="KOU88_003890"
     CDS             3819..4364
                     /locus_tag="KOU88_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213702.1"
                     /translation="MAWNLRSKSFLLSREVLKIKRDIIEEISSAAYVPDNLKYYDNVM
                     RETPGMYGRECSLDFIKKKQEKLLKLKKKVKKNYDSNINKIDSYLKILDESIIDESDH
                     VELVVFKLYLQLENVVKVTETVNDLGFRIKTNTYARERKYSTNDITSIITDPFANVVE
                     DLKILVQDRQRKNYHGNKECF"
     gene            4368..5012
                     /locus_tag="KOU88_003891"
     CDS             4368..5012
                     /locus_tag="KOU88_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK3213703.1"
                     /translation="MEAHSGQKVNPIKDIEDVFRLLNFLEEWNERNYLLALFGMCTGL
                     RIGDILALKVADVTDIKLDKKGKKIRVSKDWIRVIEEKRDYDREVFLSDVIKSAIENY
                     TQDKPGEEFLFKSGKRKKFNRPIQTRQAGRIIKGAAKKVGIKENVATHSLRKTFARHI
                     YDEEENKTYALELIRKILGHKTIEMTRRYIGIDKDEEVKAITKFTNKLKKRKRN"
     gene            5227..5685
                     /locus_tag="KOU88_003892"
     CDS             5227..5685
                     /locus_tag="KOU88_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213704.1"
                     /translation="MDVNEVEIIDSSYEKGKELTEDQCNMVTLLITGTTVTETARIIG
                     VNRKTIYNWMNKEHVRKEMDRRKQELTNQGNLMILKDLDSYINNIKELASDKSDKRVM
                     LAANQYLINRIYGTPTSTVIQAEDNSVGMGMDATEIEAAIAKIRIRTSKK"
BASE COUNT         2450 a          510 c         1075 g         1679 t
ORIGIN      
        1 ggcttgaaag tgaggcgatg aaataatgaa aaagacgtta ataatcgtag gagtagttat
       61 ttcaatatta attatgtttg cttgcttgtt cttagtaact aaaaataaag caattgattt
      121 agaagagcag gtccaatcag caactgcatc tgtagaggtg caagaaaaaa ggagaattga
      181 tttaattaag aacatagtag actgcgtaaa agactatgct aaatatgaaa atagaacatt
      241 aaaagaagta actgacatga gagtaagtgc aaatgatgaa tctatcaagg aagcaaaatt
      301 aaatatacaa gcagtagcag agaagtaccc agatttaaaa gctaatgaaa attataagca
      361 actaatgagt gagttgagta taacagaaaa tatgattgca caacatagag aaaattataa
      421 tatgcaagtt cgcaattaca ataaatatat aagaaaattt ccagcaaatt taattctaaa
      481 tagtatggga tatgaaaaaa tagaatctaa atatactgaa tataaagcaa aagaggatgc
      541 acctcaaaat ttatttgatt aagaggtgca catatgaaat ttaaaacttt tgaaataact
      601 aagagagaat ttttagtgag cataataatt gcttgcatga tgattgtgct tggatttttc
      661 attgatgata aagttcaatc aaaattttta gaagataatg aaagatatta caaagcaact
      721 aaaataaata atgacaaaga tctctttgat tatgctatgg aaacaagtgc gggagattct
      781 ttgataagtg gaagatttaa aagtgtagat tctgtatcta tagaagaatt aaaaggggac
      841 tattggttta tagaaagaac ggaagaaaaa tacactatgc atactagagt ggttaccact
      901 aaagacagta aaggccattc acataaatat actgaaacat attggacttg ggattaccat
      961 gattcaatag agaaaaaatg taataaattt aatttcatgg gtaaagagtt tgatgcgaaa
     1021 gtaattacta atttatctaa agagagattg gcattaaaga aagatatatt taaaaataat
     1081 aatcttaaaa taaaaggtaa ttatgcttac attaataata agagaaggta ctattatgaa
     1141 gttataccga aagaatttaa tggtactatg tatgctaatt taaaaaataa tactatagcg
     1201 aatccagctg ataaaaacat aaaagttttt aagggtgagt ctatacagaa tgttttagaa
     1261 aataataatt ttaatacagg gttttttaaa gtagtgtttt ggatcatctg gatattaata
     1321 actacaatca ttatatatgt attttattat ttaaaaaatg attggcttga agataaataa
     1381 agatgtaaga ggagaagatc aggtatgaaa tgtaaggtgt accatgctat taaaaatata
     1441 aaagatgcaa atgagttaat tgatagattt gaaacggaaa atatattctt tgaattaaat
     1501 aacatagata atgaaaatgt cttaaatgga gaaatggatt taactgatat agaagatatt
     1561 gcatcattgc aatttatatt agatggagat ttatttatat ttagtagttg tgatgaaatg
     1621 atatttatga ataaatacac tcaaagggag ttgggacttc aataaatgaa taagagaata
     1681 gtatgtcaag atacaaacga gattgtctat aattataaag aatatcaaaa aactaaacac
     1741 tgggaatcat taaaaaatga attctatttt tctaatgaat gtaaatgtgt tttgtgtgat
     1801 tcagtaaaga aagtgtcttt gcatcataaa acatatcgaa gaataggagc ggaagaattg
     1861 gatgatttaa ttccattatg caatagttgt cactataaag ttcatcgaaa taataaacaa
     1921 tatctattta ataaggcaac ggaaaaacag ataagatgca taaatgattt attggaagtt
     1981 tatgtagata ttgtggaaga attatttatg aatgaatata tttatcttta tgttgccatg
     2041 ggaatagaat tttacaatga aaatctaatg ttatttgaag caaatcatat tatcaatgat
     2101 cttaagtttg tttctgcaat gctgtatgag ttttatgcca caaagttgga aataaaactt
     2161 ccaggatatt tcaatggatt tgactacgaa gaaataaaag attctttata taaaaagatg
     2221 cagcgattaa gtaaatatat ttatgttccc aaaaaacaag agattgagtt attatttaaa
     2281 aaaagaaaaa aggagcatta tgaataaata tactcaaaaa gagttgggac ttcaataaat
     2341 gaatgagggg agatactaaa gatggattta aagttaatta gcagcatacc taattggaag
     2401 gtagaagatc agttggcaaa aattgatgaa gaggtaactg agtttaaaaa tgctatagat
     2461 acaggaataa ctaaagatat aattgcagaa ggattagatg tttgtcaaac tattttaaca
     2521 atgtttcaag ttttagaaat agaaaactat attactgaag gagtagagac acataataag
     2581 aaactaaatg gaagaggatg ggatctcaaa gaaataggag acgatatact taatttaatt
     2641 aaaaattcaa tgattaatga attgattaat atgaacaaga aattaaaatg ccttgatgaa
     2701 aaagaattta atgcaaaaat acaattttta gatgtagata aactatggaa tttgtgcatg
     2761 cctttagtta acttaagtac tataaaagga gttaatgaaa gcattgatga aatgaaaatg
     2821 ggagagtttc taaaaaatat taattaaagt aaggagataa tataatatgt tgatagaagt
     2881 aactgaaaat aatagagaat taaaagtagg agatattgtt gaaattaatg gtggtaataa
     2941 gttatatatg attctttctt taaaggaaac aataggtggg tatgttatta taaatatgca
     3001 gaatggatat ggttcatttg gtgcttataa aagtttaagt caactagaat tagacttgaa
     3061 ggtaagaggt tataaattat atagttctga tgattacaag ttgcaattag tgcctagaga
     3121 ataagatata tttcaaaaaa gaaaaaaagg agcattactt cacactcctg cttgtcaaaa
     3181 ttctaaaacc gttatcacaa catcattata acataattag gagtgtgagg taatgcaatc
     3241 tagcaaaaaa gacaatttgt ttagtagtgc agaaggtaag ttatataatt ataaaaaaat
     3301 aaaagcggaa atagaaaaaa tagacattga tatgcagatg ataaaaaacg actacagagg
     3361 atgtagtgga gttgaaatta aagaaaagac aagcaagaca tatgatatta aaagtgtaat
     3421 tgaaatagag actgaagaaa aagaaaagaa aattgcctta aaagaaaaag agaagagaca
     3481 taaagagttg ataatagaaa aaatagataa tgcaatgaaa atattaagtg aagaagaaaa
     3541 aaagatagta cagtataaat acttttcaag tagcaggaca tcttgggaat atgttggcag
     3601 aatgattggt ttttcagcga gtaagtgtaa gcaaatgagg tttgatatta tagataagat
     3661 aaaaggattg ctataaaaat gtccgatttg tgacgatttt aaaccgattt atgtctgttt
     3721 tgtgtctaaa aaatgtccga tttgtgacca atttatgtct gttttgtgtc ttttaatcat
     3781 gataagattg tattgtgaga aaaatatatt taataaaaat ggcttggaat ttacgttcta
     3841 agtctttttt attgtctaga gaggtgttga agattaaacg tgatataata gaagaaattt
     3901 caagtgctgc atatgtacca gacaatctaa agtattacga caatgtaatg agagaaactc
     3961 ctggtatgta tggaagagaa tgttctttag attttataaa gaaaaagcaa gaaaaactct
     4021 tgaaactaaa aaagaaggtt aagaaaaatt atgattctaa tattaataag atagactcat
     4081 atctaaaaat tttagatgaa agtataattg atgagtctga tcacgttgag ttggttgtat
     4141 ttaaattata tttgcaatta gaaaatgttg taaaagtaac tgaaactgta aatgacttag
     4201 gatttagaat aaagaccaat acttatgcaa gagaaagaaa atatagtaca aatgatataa
     4261 cctctataat cacagatcct tttgctaatg tagttgaaga cttaaaaata ttggtgcaag
     4321 ataggcaaag aaaaaattat catggtaata aggagtgttt ttaatgaatg gaagcacata
     4381 gtggacaaaa agttaatcca ataaaagata tagaggatgt atttagactc ttgaattttc
     4441 tagaggaatg gaacgaaaga aattacttat tagccctctt tggaatgtgt actggactta
     4501 gaataggaga tatattagca cttaaagttg cagatgtaac agatataaag ttagataaaa
     4561 aaggaaaaaa gataagagtg tctaaggact ggattagagt tatagaagaa aaaagagact
     4621 atgatagaga agttttctta tctgatgtaa taaagagtgc tatagaaaac tatactcaag
     4681 ataaaccagg agaagaattt ttatttaaaa gtggcaagag gaagaaattt aatagaccta
     4741 tccaaacaag acaagcagga agaataataa aaggagcagc aaaaaaggta ggaataaaag
     4801 aaaatgttgc aacacactct ttaagaaaaa catttgcaag gcatatttat gatgaagaag
     4861 agaataagac ttatgcatta gaacttataa ggaagattct aggacataag acaatagaaa
     4921 tgactagaag atatatagga atagataagg atgaagaagt aaaagcaata actaaattta
     4981 ctaataagtt aaagaaaaga aaaagaaatt aaaatatctt gtattttatc taaaatttaa
     5041 tatgttacgt ttttcaacaa caggacatta ttagaatgca aagagcctta acaatagagt
     5101 ttacaaggaa tagaatagat ttattaaaat gtctgaaaat atatattaaa ggtcatttat
     5161 tcaagggatt tatagggatg tagatattta aatgtttatt tagaagctga gtaaagaggt
     5221 gattaattgg atgtgaatga agttgaaata atcgacagta gctatgaaaa aggtaaagag
     5281 ttgacagaag atcagtgcaa tatggtaact ctattgatta caggtactac agtaacagaa
     5341 actgccagaa ttattggagt aaatagaaaa acaatctata attggatgaa taaagagcat
     5401 gttaggaaag aaatggacag acggaaacag gagctaacaa accaagggaa cttaatgata
     5461 ttaaaggatt tagatagtta tatcaacaat atcaaggaat tagctagtga caagagcgat
     5521 aagagggtta tgttggcagc caatcagtat cttataaatc gtatatatgg aactcctaca
     5581 agtacagtta tacaagcaga ggataatagt gttggcatgg gtatggatgc aacagagata
     5641 gaagcagcta tagctaagat aagaataaga acaagcaaga agtaattaga tatgaaataa
     5701 atcctgcaag aata
//
LOCUS       DAFAZV010000101         5693 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFAZV010000101 DAFAZV010000000
VERSION     DAFAZV010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5693)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5693)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5693
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.104"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            122..238
                     /gene="rrf"
                     /locus_tag="KOU88_003893"
     rRNA            122..238
                     /gene="rrf"
                     /locus_tag="KOU88_003893"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(452..1636)
                     /locus_tag="KOU88_003894"
     CDS             complement(452..1636)
                     /locus_tag="KOU88_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK3213705.1"
                     /translation="MLSKRLNFITPSYTIGISSKVKEMESNGVKVINLSIGEPDFNVP
                     NNAKSYGIDSLNKDYTKYDLVPGLKILREEICKKLIEENNCNYSIDEIVVSSGAKNSI
                     TNTLLALTDEGDEVLLPKPYWVSYPEMIKLVNAVPVFIDTKKENGFKLTKEELEKSIT
                     DKTKILVINNPSNPTGSVYTKDELIEIVDVCIQNKIYILADEIYEKICYTGEFTSIAS
                     LSEEAKDITITINGFSKSAAMTGLRLGYTASNKTIAKAMSSIQGHLISHPSLTAQYIA
                     YGALKDCSIDIDNMVKTYKSRRDLIKSKLDSIDNVGYVNPNGAFYIFIDLSKVSEKFE
                     YKDSFSIEFCNQFLEEYNVAVVPGIAFGMDKYIRISYACSENTFLSGLDKLKEFVYKI
                     MA"
     gene            2009..4360
                     /locus_tag="KOU88_003895"
     CDS             2009..4360
                     /locus_tag="KOU88_003895"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="HBK3213706.1"
                     /translation="MVEFVKKRDGRVIPFNEDRITRAIFLAATNVAEREGIVPDYKLS
                     EQLTQEVIKFLNHKYSESVPSVEDIQDSVVKVLIETGHAKTSEEYIIYRTERSRIRNS
                     KTRLMKAIEEITFEDAEDADIKRENANINGNTAMGTMLQYGSTVSKEFCKTHILKPEH
                     SFAHDNGDIHIHDMDFLNMGTLTCCQIDVKKLFNGGFSTGHGFLREPQDIISYGALAA
                     IAIQSNQNDQHGGQSIPFFDYGLAEGVYKTFKKFYIGNLAKALKLFKGIENNDVIKNI
                     VYNTEKETNQKVGLKRDELYLNLEKEKLIQTFDIDDELVNKMQNFAFEESYRETDKKT
                     YQSMEAFIHNLNTMHSRAGAQVPFSSVNFGTDTSEEGRMVTKNLLLSQERGLGNGETP
                     IFPILIFKVKEGINLNPEDPNYDLFKLSCRVSAKRLFPNFSFLDAPFNAKYYKKGEPD
                     TEATYMGCRTRVLSNVCGSETVSGRGNISFTTVNLPRLGIKHGIINNEKANLDGFFEE
                     LDEKINLIIEQLLERLEVQGNKKMKNFPFLMGQGVWKGSDNLGPEDTLKEVIKQGTLT
                     IGFIGLAECLIALIGKHHGESKEAQELGLKIVSHMRHKMDEATDKYKLNFSLMGTPAE
                     GLSGRFTKIDKKVYGEIKGITDKEYYTNSFHVPVYYNISAYDKIEIEAPYHELTNAGH
                     ITYVELDGDPSDNLEAFETVIKAMKDLGIGYGSINHPVDRDPICGFSGVITSNICPVC
                     GRNEDESDIKFERIRRITGYLVGTVDRFNNAKKAEVRDRVKHR"
     gene            4382..4921
                     /gene="nrdG"
                     /locus_tag="KOU88_003896"
     CDS             4382..4921
                     /gene="nrdG"
                     /locus_tag="KOU88_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBK3213707.1"
                     /translation="MKIRMSSTISYDSIVDGPGLRMVIWTQGCIHNCKECHNPQTHDL
                     CGGFYMDTEEIINKVKSLKLQKGITLSGGEPFLQPEPLEEIAREAKINGLDVWSYTGF
                     TFEQLLDKKNRAYFKNLNLLKQIDILVDGKFIAEKKDISLKFRGSSNQRIIDVQKSLK
                     YKKVFLVEQYMKDDLSIAE"
BASE COUNT         2217 a          649 c          917 g         1910 t
ORIGIN      
        1 tttgatgttc attcattaag atatatgtgt agtttttaga gtgctaactc taaagaaact
       61 agtattacta ggttctataa acttattaaa aacttaatag aaatattaag cataaagatt
      121 atgtggttac aatagcagag aggatacacc tgttcccatt ccgaacacag aagttaagct
      181 ctctagcgct gatggtactt ggtgggaaac tgcctgggag agtaggacgt agccacgtaa
      241 tttttttgtt ataataaatt tagaatttaa cttatatagt ttaatttgat aatttgatga
      301 aaaaaataaa agacttactg atttttaaat ctataggtct tttatttttt atctaacatt
      361 taaattaagt tgttgaatat atcttatatt acttacctta tatattaatt accattaata
      421 cattatatct aattactatt catctaaatt actatgccat tattttatat acaaattctt
      481 ttaatttatc taatccagat aagaaagtat tttcactgca agcataggat atacgaatat
      541 atttatccat accaaatgct atgccaggaa caactgcaac attatattct tctaaaaatt
      601 gattacaaaa ttctatagaa aaactatctt tatattcaaa tttctcagat actttagaaa
      661 gatctataaa tatatagaat gcgccatttg gattcacata tcctacatta tcaatagagt
      721 ctagttttga tttaattaaa tctcttcttg atttatatgt tttaaccata ttgtctatgt
      781 caattgagca atctttcaag gctccatagg ctatgtattg tgctgttaga cttgggtgag
      841 atataagatg tccttgtata gaactcattg ctttagcaat cgttttatta gatgcagtat
      901 atcctaatct taatccagtc attgcagctg acttagaaaa accatttata gttattgtta
      961 tatctttagc ttcttcgctt aatgatgcaa ttgatgtaaa ttcaccagtg tagcatattt
     1021 tttcatatat ttcatctgct aaaatatata ttttattttg tatgcataca tctactattt
     1081 ctattaattc atcttttgta taaacactac cagtaggatt tgaaggattg tttattacaa
     1141 gaatttttgt tttatctgtt atagattttt caagttcttc ttttgttaac ttaaatccat
     1201 tttctttttt agtatcaata aaaactggaa cagcattaac taacttaatc atttcaggat
     1261 aactaaccca ataaggcttt ggtaataaga cttcatctcc ttcgtctgtt aaagctagta
     1321 aagtatttgt tattgagttt tttgctccac ttgatacaac tatttcgtct attgaatagt
     1381 tacagttatt ttcttcaata agttttttac agatttcctc tctaagtatt tttaatcctg
     1441 gaactaaatc atatttagtg taatctttat ttaaagaatc aataccataa gattttgcgt
     1501 tattaggtac attaaaatcg ggttctccta tactaagatt tattacttta actccattac
     1561 tttccatttc tttaacttta gaactaatac ctattgtgta ggatggtgtt ataaagttta
     1621 gtctttttga taacataaaa tgcctccttt taaattatta tttatattat acgacaaatt
     1681 taaagaattt acataaggaa atttgtagat atatacatta atatatataa tagcctacac
     1741 tttttgccta aaattagtgt aaaaaaaaga gaaaaaaatt ttaactttca aagttgttag
     1801 aaacgctgct gttcaaaata tccacatagt atttgcaatg atttgcgcaa gtttgactat
     1861 tatgtacaaa tttggtaatc ttaatatagc aattattaag ataatccctt taacttagtt
     1921 gaaggggatt tttttagact taacatacta catatagtgg tatggggatt aataaaatac
     1981 aatatatagt aacaggaggt ttttttaatt ggttgaattc gtaaaaaaaa gagatggaag
     2041 agtaattcca tttaatgaag atagaataac aagagctata tttttagcag caacgaatgt
     2101 tgcagaaaga gaaggaatag tacctgatta taaattatct gagcaattaa ctcaagaagt
     2161 aataaagttt ttaaatcata aatactcaga atcagttcca agtgttgaag atatacaaga
     2221 ttctgtagtt aaggttctta tagaaactgg ccatgcaaaa actagtgaag aatatataat
     2281 atacagaact gaaagaagta gaataagaaa ttcaaaaaca aggttgatga aggcaataga
     2341 ggaaattacc tttgaagatg cagaagatgc tgatataaaa agagaaaatg caaatattaa
     2401 tggtaataca gcaatgggaa ctatgttaca atatggaagc actgtatcta aagaattttg
     2461 taaaacacat atattaaaac cagagcattc ttttgctcat gataatggag atatacacat
     2521 acatgatatg gattttttaa atatgggaac attaacttgt tgtcaaatag atgttaaaaa
     2581 actattcaat ggtggatttt caacaggaca tggcttttta agagagccac aagatataat
     2641 aagttatggt gcattagctg caattgctat acaaagcaat caaaacgatc aacatggagg
     2701 tcaaagtata ccatttttcg attatggatt ggctgaaggt gtatataaga catttaagaa
     2761 attctacata ggaaatttag ctaaagcatt gaagttattt aaaggaattg aaaataatga
     2821 tgtgataaag aacatagtat ataatacaga gaaagaaaca aatcaaaaag ttggtcttaa
     2881 gagagatgaa ttgtatctaa acttagaaaa agagaaatta atacagactt ttgatataga
     2941 tgatgaactt gtaaataaga tgcaaaactt tgcatttgaa gaatcgtata gagaaactga
     3001 taaaaaaaca tatcaatcta tggaagcatt tatacacaat ctaaacacaa tgcactctag
     3061 agcaggtgca caggtaccat tttcaagtgt aaacttcgga acagatactt ctgaagaagg
     3121 aagaatggta actaagaatc ttctattatc tcaagaaaga ggtttaggta atggagagac
     3181 accaattttt ccaattttaa tatttaaggt caaagaaggc ataaatttaa atcctgaaga
     3241 ccctaattat gatttattta aattatcatg cagagtatca gctaaaagac tattccctaa
     3301 ttttagcttt ttagatgcgc cttttaatgc aaaatattat aaaaaaggtg aaccagatac
     3361 agaggctaca tatatgggtt gtagaacaag agtacttagt aatgtgtgtg gttcagaaac
     3421 agttagtggt agaggaaaca tatcttttac tacagtaaat ttaccaagat tgggtataaa
     3481 acatggtatt ataaataatg aaaaggctaa tttagatggt ttctttgaag aattagatga
     3541 gaagataaac ttaattatag aacaattatt ggagcgcctt gaggttcaag gaaataaaaa
     3601 gatgaagaat tttccattct taatggggca aggtgtatgg aaaggttctg ataatttagg
     3661 accagaagat acactaaaag aagtaataaa acaaggaaca ttgacaattg gatttatagg
     3721 tttagcagag tgccttattg ctcttatagg taaacatcat ggagaaagta aagaagctca
     3781 agaattagga ttaaaaatag tgtcacatat gagacataaa atggatgaag caacggacaa
     3841 atataaatta aatttctcct taatgggtac tccagcagaa ggtctttcag gtaggtttac
     3901 taaaatagat aaaaaagttt atggagaaat taaaggtatc acagataaag aatattatac
     3961 taattcattc catgtaccag tttattacaa tataagtgca tatgataaaa ttgagataga
     4021 agctccatac catgaattga ctaatgcagg tcatataaca tatgtagagt tagatggaga
     4081 tccatctgat aatttagaag cttttgaaac tgttataaaa gctatgaaag atttgggtat
     4141 aggatatgga agtataaatc atcctgtaga tagagaccca atatgcggtt tttcaggtgt
     4201 aataacaagt aatatatgcc ctgtatgtgg aagaaatgaa gatgaaagtg acatcaaatt
     4261 cgaaagaata agaagaataa caggatactt agttggtaca gttgatagat ttaataatgc
     4321 taaaaaagca gaagtaagag atagagtaaa acatagatag ttttatttgg gggaataagt
     4381 tatgaaaata agaatgtcat ctactataag ttatgacagc atagttgatg gaccaggatt
     4441 aagaatggta atatggactc aaggatgtat tcataattgt aaagagtgcc ataatcctca
     4501 gacacatgat ttatgtggag gattttatat ggatacagaa gaaattataa ataaagtcaa
     4561 atcattgaaa ttacaaaaag gcattacgct atcaggagga gaaccatttt tacaaccaga
     4621 accattagaa gaaatagcaa gagaagctaa aataaatggg ttagatgtat ggtcatatac
     4681 tggatttacg tttgaacaac tgttagataa aaaaaataga gcgtatttta aaaatttaaa
     4741 tttactaaag caaattgata ttttagtgga tggaaaattt atagctgaaa aaaaagatat
     4801 aagcttaaag tttagagggt catcaaatca aaggataatt gatgttcaaa aaagtttgaa
     4861 atataaaaaa gtgtttttgg ttgagcaata tatgaaggat gatttatcta tagcagaata
     4921 aaatataaat aaacaggatt aaatatatgc atatatttaa tcctgtttat tttcatataa
     4981 tatttcaagc ttgtataatg taacaattaa accaaaagac tcattgtata tttgaaatta
     5041 agttttttat agtttatagg tgttttatgt ggattacgaa tgatatagta tcgatacatt
     5101 atttaataga ttcttatgcc aagaaacaat taatttatag aaattcttaa ttgttacaat
     5161 ataaatatct agataagtta taagatactg ataaataatt tataaagttt attaatctaa
     5221 tattgtgtgt gaatattaag tggtcaagta gtctaaaaaa tgaaaaagat ttaaaaaagt
     5281 gttttaacta aacacataag tgttaaattc atgtataagt ataggttaga tacataagaa
     5341 ataattatgt aatatctatc tttgtaaaaa aatattaaat tttgtaattt gtggataaat
     5401 atgtttataa tgtggataat atttaatgta ataagttaaa gcaatatgaa tcaactgttt
     5461 ataatgtgga taatattata aatgtatgaa taattgcagt atttaaaaac aaaaaaagtt
     5521 aaaaaagttg ttgactctaa aagaaaaagt tggtatagta atacttgtcc tcaagaaaag
     5581 ggcaaacaaa taaagcacaa agaactttga aaattaaaca gtaggttaat ttataaaaca
     5641 agaaacaaac cataaagcca gatattttga taacaatagt atctgagcct gat
//
LOCUS       DAFAZV010000102         5635 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFAZV010000102 DAFAZV010000000
VERSION     DAFAZV010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5635
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.105"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(739..2145)
                     /locus_tag="KOU88_003897"
     CDS             complement(739..2145)
                     /locus_tag="KOU88_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3213708.1"
                     /translation="MDSVKYILRRFIGSSILISLLFIVLNIAGFLLFSYMLFVSKYSD
                     NLDTSDSREIKSNLIMIEDNLVLKDGKFILDDSSKEILHKNKVWAMLIDNNGDRIWGF
                     DLPKEIPSHYTLTDVAKFSRFFLKDYPVYVWEHPNGILVTGYPKDKYTKFNLTYTVKE
                     IEQFPMLIIGMFLVNAIVTFLIALFIGLKMVKSIKPIITGIKLMSKGEPVLLQEKGIL
                     SDISKSINTVSKELQMKDEKLRKKEEARSNWIAGISHDIRTPLSMIIGYAGELEESSS
                     LSNREQEQVSIICNQGIKIRELVNDLNLVSKLEYNMQALNCDKIRVSAFLRELISEFI
                     NNNLDNDFYVELDILNEDIIIDADKKLLKRAISNLIQNSITHNQQGCNIRVTSKSDLD
                     FCYIIVEDDGKGMSQERINSLLKSQNGLSEAYAKGQNHGLGILIVSGIINAHRGKLDI
                     TSIDSQGLKTILKLPLIK"
     gene            complement(2190..2897)
                     /locus_tag="KOU88_003898"
     CDS             complement(2190..2897)
                     /locus_tag="KOU88_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213709.1"
                     /translation="MESIKDKKILVVDDHKELLKMIDEILRKEGFSRVFLASSYEEAV
                     KVFRNVKPDCAILDVVLPDGDGFSIMRKIRETSKIPVIFLSARGEDEDRLIGLGLGAD
                     DYIVKPFLPKELTLRLVGILNRVYVPIEEEELPVFKLGDSVVVNLNSACVEKEGQEIS
                     LTAKEHSLLLKLYENKGRIVTNDSLCQAIWGDDMYGYENTLMVHVRRVREKIEKTPST
                     PKHLITVRGLGYKLMIN"
     gene            3068..3982
                     /locus_tag="KOU88_003899"
     CDS             3068..3982
                     /locus_tag="KOU88_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213710.1"
                     /translation="MEMIIRTQRLSKEYNKIFRVKDIDLRVPQGAVYGFLGPNGAGKS
                     TTLKMLLGLAKPTQGNINILGKELNEKNRISILKDIGSLIESPSYYGHLTGLENMTIM
                     QRLLDLPKKNVNEALKIVRLENQKNKKVSQYSLGMKQRLGIAMAIMKFPKLLILDEPT
                     NGLDPAGIEEIRELIKSLPEKYGMTVLISSHLLSEIDQIATSIGIINHGELVFQDSIK
                     ELHNRGQSQIAIKTKNVVSAQKLLNTKGYMSLIQDGYLTIENLKDSDVAKINGMLVHS
                     NIDVFRIEEHKKSLEDIFLELTGKAVTL"
     gene            3982..4743
                     /locus_tag="KOU88_003900"
     CDS             3982..4743
                     /locus_tag="KOU88_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213711.1"
                     /translation="MKYLGLEFYKLKRKKIILMTFLFAAVEIMWCIVNSNRAITRNPD
                     MLGGFEYSYMLMSFASLNGLFFPILISIITSRISDIEHKGDTWKLLKSSVTSLNSIYL
                     SKFLCSAILVSIPVLMQVLSIVLFGHFRGVIESISVSLLLKYTLGTILVSIAIIALHL
                     WIATVIPNQMIAITFGMIGSFIGLTSGLFYQGIRRLFIWSYYLELSPLSYAYDNVLGS
                     SVYRIDMNFSITILVFLIGMLIYYIGRNHLLKKEV"
     gene            4755..5492
                     /locus_tag="KOU88_003901"
     CDS             4755..5492
                     /locus_tag="KOU88_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213712.1"
                     /translation="MLRKSVLGEILKLKNSFIWYVLLALPLISVLIGSGNFYLNQGIL
                     KKEWYSLWTQVSLFYGEFFFPILIAIFCAYICRLEHMNHNWNNVMTLPVNLKNIFLSK
                     LTVVSILTAITQVFFVIFYIVAGNMFGFSGSVPKELTGWIAKGWIISISIASIQLYMS
                     IKIRSFATPIGISLCLSLFGMGLIVAKPAVGIFFPYSMLGSAMGVIKQSALNVNDTIV
                     TICVAFITTIVFSEIANRNFRKNDVIS"
BASE COUNT         1949 a          858 c          712 g         2116 t
ORIGIN      
        1 actttctaaa tttcttgctt cttaagaata atgttaattt taattttaag attatagttt
       61 ttaccttgtt taattgaaac attctatata attatatcct tctattttag agttttttta
      121 tttatatatt acaaagttta aattttttca ttaattatat tataaatttt ccatatattt
      181 caacataaat acatatatat atatgttatt tctaaaaata ctacacaaaa actctacttt
      241 agtagaactt aatggcgcaa aatacttcaa tttaaaacat ttatcgtact ttaaataaat
      301 aactataata atatacttac aatagttaca tagaagctat tataactaca cagaacagcg
      361 tataattaaa acttttttag gatgtcatta tattttttct taaaattaaa aaacactata
      421 ccataattct attttagtag aatttttttg tcaataataa aattaaatat taactaaaaa
      481 ataaaaaaaa tggaattatc taaagaattt aataacctta caataattcc aaaatattat
      541 ttctatgaaa attttgatac catgagtaac tcagccataa gcgcataaag cacaagttac
      601 tctttacttt aataaaactt gacaagaaaa gaatttatcc ttattctact ctaatagagt
      661 taatttgtca ataaagaata aaattatttt caaaatattt tcattcttca ttcttatctg
      721 ttattatttt ataaaatatc acttaattag aggtaatttt agtattgttt ttagtccctg
      781 actatcaatg ctcgtaatat ctaatttacc tctatgtgca ttaataatgc cagatactat
      841 caaaatacct agaccatgat tttgaccttt ggcatatgcc tcacttagtc cattttggct
      901 ctttaataaa ctattaattc tttcttgact catacctttt ccatcatctt caacaattat
      961 atagcaaaaa tctaaatcag acttagaggt aacccttata ttacatcctt gttggttatg
     1021 agttatacta ttttgtatta aattactaat agcccttttt aataattttt tatctgcatc
     1081 tataataata tcttcattta gtatatcaag ttcaacgtaa aagtcattat ccaaattatt
     1141 atttataaac tcagaaataa gctctctcaa aaacgcagaa actctaatct tatcacaatt
     1201 caatgcttgc atattatatt caagtttaga cactaaattt aggtcattta ctaattctct
     1261 gattttaatc ccttgattgc atataataga cacttgctct tgttctctat ttgaaaggct
     1321 actgctttct tcaagttctc cagcatatcc aattatcatt gaaagtggag ttcttatatc
     1381 atgagatatt cctgcaatcc agttagacct agcttcctct ttcttcctaa gtttttcatc
     1441 tttcatttgc aactctttag atacagtatt aatagatttt gaaatatcac ttagtattcc
     1501 tttttcttgt aaaagtactg gctctccttt tgacataagc tttatgccag taataattgg
     1561 ttttatagat ttcaccattt ttaaacctat gaatagagct attaaaaaag taactattgc
     1621 attaaccaaa aacataccta ttattaacat aggaaattgt tctatttcct taaccgtata
     1681 agtaaggtta aacttagtgt acttgtcttt tggataacct gttactaata ttccatttgg
     1741 atgttcccat acatacacag gatagtcctt taaaaagaac cttgaaaact ttgctacatc
     1801 tgtcaaagta taatgacttg gaatttcttt tggtaaatca aatccccata ttctatctcc
     1861 attgttatca attaacattg cccaaacttt atttttatgt agtatttcct tactagaatc
     1921 atctaaaata aactttccat cttttaaaac caaattatct tcaatcataa tcaagtttga
     1981 ttttatttct ctgctatcac ttgtatctaa attatcagag tatttagata caaataacat
     2041 atatgaaaac agaagaaaac ctgctatatt taatacaata aaaagtaatg aaatcaagat
     2101 acttgaacct ataaatcgcc tcaatatgta ctttacacta tccaaaatta aatcactcct
     2161 cttgatttct tttattctaa tatctaaaat taattaatca tcaacttata tccaagacct
     2221 cttactgtaa taagatgttt aggtgtagat ggagtttttt ctatcttctc tctaaccctt
     2281 ctaacatgaa ccataagggt attttcatat ccatacatat catctcccca aatggcttga
     2341 catagtgaat cattagtaac aattctccct ttattttcat acaactttaa aagcaacgaa
     2401 tgctctttag ctgttaaaga aatctcttgc ccttctttct caacacatgc actatttaaa
     2461 ttcacaacaa cagaatctcc cagtttaaat actggcaact cctcttcttc tataggcaca
     2521 tatacacgat ttaatatacc cacaagcctt aaagtaagtt cctttggtaa aaatggcttt
     2581 actatataat cgtcagcccc taagcccaaa ccaatcaatc tatcttcatc ttcacctctt
     2641 gcagagagaa aaatcactgg tattttagat gtctctctaa tttttctcat aatagaaaaa
     2701 ccatctccat ctggcaatac aacatctaaa attgcacaat ctggctttac atttctaaat
     2761 accttaacag cttcctcata acttgatgct aaaaatactc tactaaatcc ctcttttctc
     2821 aggatttcat ctatcatttt taataattcc ttgtggtcat caaccacaag tattttttta
     2881 tcttttattg actccataat catcaccctc ctttagtata ccatataccc attttcacaa
     2941 ctttgcctaa atagactttt aaggttattg taaggtaaat ttcagctaat tgaaatgtaa
     3001 ccaagttatt atactgatat aagttaaaag aatcaataag cacagattaa aaaaggggat
     3061 gaaacatatg gaaatgataa ttagaacaca aagactttca aaggaataca ataaaatatt
     3121 tagagtaaag gatatagacc taagagttcc acaaggagct gtatatggtt ttttgggtcc
     3181 taatggagct ggaaaatcta ccactcttaa aatgcttctt ggacttgcta aacccacaca
     3241 aggaaatatt aatattttag gtaaagagtt aaatgaaaaa aatagaatat caattttaaa
     3301 agatataggt tctttgatag aatctccatc atactatggt catcttacag ggcttgaaaa
     3361 catgaccata atgcaaagac tcttagattt acctaaaaaa aatgtaaatg aagcattaaa
     3421 aattgtaagg ttagaaaatc aaaaaaataa aaaagttagt caatattctt taggtatgaa
     3481 gcaacgtctt ggtattgcta tggcaataat gaagtttccc aaattattaa tacttgatga
     3541 acctacaaat ggactcgacc cagcagggat tgaggaaatt agagaattaa taaaatctct
     3601 accagaaaaa tacgggatga ctgttctaat ctctagccat cttttaagtg aaattgacca
     3661 aattgccaca tcaataggaa taataaatca tggcgaactg gtttttcaag atagcataaa
     3721 agaacttcat aatagaggtc aaagtcagat tgctatcaaa actaagaatg ttgtatctgc
     3781 acaaaaacta ttaaatacta aaggatatat gtcacttata caagatgggt acttgactat
     3841 tgaaaattta aaagactcag atgtggctaa aataaatggt atgcttgtcc attcaaatat
     3901 agatgtattt agaatagaag aacataaaaa aagcttggaa gatatattct tagaacttac
     3961 tggtaaggcg gtgactttat aatgaaatac cttggtctag aattttataa acttaaaaga
     4021 aagaagatta ttctgatgac ctttttattt gcagctgttg aaataatgtg gtgtatcgta
     4081 aattcaaata gagctattac acgtaatcca gatatgttag gtggatttga atattcctat
     4141 atgcttatga gttttgcaag tttaaatggt ctattctttc ctatcttaat atcaataatc
     4201 acatcacgta taagcgatat agaacataaa ggagatacat ggaagctttt aaaatcttct
     4261 gtgacatctt taaatagtat ttatttatct aaatttttat gttctgctat tttggtatct
     4321 atacctgtat tgatgcaagt gttatctatt gtgttgtttg gacattttag aggggttatt
     4381 gagtcaattt ctgtatcttt acttttaaaa tacacattag gaacaattct tgtaagtatt
     4441 gctatcattg cactacacct atggattgca actgtaattc caaatcaaat gattgcaatt
     4501 acatttggca tgattggtag ttttataggt ttgacatcag gtttgtttta tcaaggtatt
     4561 cgtagattgt ttatatggtc ttattaccta gagttatcac ctttaagtta tgcttatgat
     4621 aatgttttag gttcatctgt ctatagaatt gatatgaatt tttctatcac gattttagtt
     4681 ttcttaattg gaatgctaat ttattatatt ggaagaaatc atttattaaa aaaagaagta
     4741 taggagggat ttaaatgtta aggaagtcag tcttgggaga aattctaaag ttaaaaaatt
     4801 cttttatatg gtatgtatta ttagctttgc cacttataag tgtgttgatt ggttctggta
     4861 atttttatct aaatcaaggc atactcaaaa aagaatggta cagcttatgg actcaagtta
     4921 gtctttttta tggggaattt ttctttccta tcttaattgc aatcttttgt gcatatattt
     4981 gtaggcttga acatatgaat cataattgga ataatgtaat gacactgcca gttaatttaa
     5041 aaaatatctt tttatctaaa cttacagtag tttcaatact tacagctatt acacaagttt
     5101 tctttgttat cttttatata gttgcaggaa atatgtttgg tttttctggt agtgtaccta
     5161 aagaattgac tggttggatt gctaaaggtt ggattatttc tatttcaata gcttctatac
     5221 aattatacat gtctataaag attagaagtt ttgcaactcc tattggtatt agtctttgcc
     5281 tttctctatt tggtatggga ttaatagtag caaaacctgc tgttggtata tttttccctt
     5341 attctatgtt aggtagtgct atgggggtta taaagcaatc tgctttaaat gttaatgaca
     5401 ctatagttac aatatgtgtt gcatttatta ctactatagt attttctgaa attgccaata
     5461 gaaattttag aaagaatgat gttatttctt aatggtaaat gctagatatt tttgggtttg
     5521 aaatttatat tctttttagt tgaaatctat atccatttta tttaaaaata tatatctttt
     5581 atttgaattt tatatgtttt atctactcgc tatataatag atatactcct aaaat
//
LOCUS       DAFAZV010000103         5589 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFAZV010000103 DAFAZV010000000
VERSION     DAFAZV010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5589
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.106"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..117
                     /locus_tag="KOU88_003902"
     CDS             <1..117
                     /locus_tag="KOU88_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3213713.1"
                     /translation="IIIREWICPSCNETHDRDINASINILKEGLRLITIQNK"
     gene            244..1146
                     /locus_tag="KOU88_003903"
     CDS             244..1146
                     /locus_tag="KOU88_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HBK3213714.1"
                     /translation="MLPQDYYGLIVILGVILGVMGAFYNWFTLYVQSLYKKIPKIGTF
                     GKLLIPFIMAGILGLVMPDVLGSGHNLVEELTSHEYIFGMVVLIFVIRFIFSAVSFGS
                     GAPGGIFFPLLVLGAFIGGIFGMVGVKVFGMNPDYVNNFVLLAMAGYFTAIVRAPLTG
                     IILIFEMTGSVSQMLSLSVISIVAYIVATLMKSKPIYESLLERLLEKNGEPVHKDRGE
                     KILDQFSVMFGSPVANKAIQDVQWPENCLLVAIQRGGEEIIPRGKTILRPSDVIVTMT
                     DERDSGAVYDKMENLCKEHTAHIF"
     gene            1758..2771
                     /locus_tag="KOU88_003904"
     CDS             1758..2771
                     /locus_tag="KOU88_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M56 family metallopeptidase"
                     /protein_id="HBK3213715.1"
                     /translation="MVSSFLNDIFRTILVSCIFIVILLVFRITLFKTFSKKFNYYIWL
                     IVIIKLSLPFMNYTFIFNESKYNGNINKISLGNFNSISIVYSTVLVSVWIAITIFYLV
                     YTLLKYIKLKNMINDLSYDVEDDKIKNLYENLLKELKINKKIRLKYSYEVESPVFFNS
                     CVILPPCDYTLKELNWIFRHELMHFKSKDLYIKYLVIFLKCVYWFNPFVYIMEKFIDL
                     DCEFYCDERVLKNCTIEEKQDYALTIISAMRKGSNSSNKFVAGLHKESDIKKRVFSMF
                     NEKYRNGILIAVILCLLSSITYFKIDLITTKSIFYPLSKQTPIENRTNSKPTYQVNVY
                     IDN"
     gene            3123..3692
                     /locus_tag="KOU88_003905"
     CDS             3123..3692
                     /locus_tag="KOU88_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HBK3213716.1"
                     /translation="MKKKLEDMTLEELWNLFPIFLTTHKECWKNWFKEEQYRLTGILP
                     MQKIVRISHIGSTSVSTIYAKPIVDILIEIIPDYNMKDIKDLIESNGYICMSESSSRL
                     SLNKGYTVDGFEERVFHLHIRYVGDNDELFFRDYLIDHPDVAKEYEKLKLDLWKKYEH
                     NRDAYTDSKLDFVREFTEKAKVLYSNRYN"
     gene            complement(4028..5365)
                     /locus_tag="KOU88_003906"
     CDS             complement(4028..5365)
                     /locus_tag="KOU88_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK3213717.1"
                     /translation="MGTYSLISTSINFILILINIFIAFFLYKLTSYFIDFRNHWIFKI
                     ILILGYSIISQMIIWLSDPINILFTLFGYFILLIICSKSKLIPIISVVMILYPIIIGL
                     NFLFINNPIYEELIHSKEYILILSIVQIISALIKLLFWFLIHIFLKNRLVNIKQYLSN
                     KIWIFIDMVCISSFLSILIAIILPPTNLIPMGSNKNIILGNLPYGTYLIILSAILANI
                     GVILLLQPLIENVKMKIEKQANHLKEKYYNLLENQQIQIRKMRHDMNNHFQMIESYLE
                     IEDIAGAKKYFNQLKIGIGTLSGKQFCKNQALNSILNLRHTSLEENGVDVHFNIDIDN
                     HLGIEPIDLCTIFSNSLDNAIEASLKIPDLSNRKVVLKARCEKEYFSYLLTNNKVNPI
                     NRKQELFISDKKDSNSHGYGIENIREIVNKYNGKLDISYTESEFSLFLYIRLF"
BASE COUNT         2084 a          556 c          918 g         2031 t
ORIGIN      
        1 attattataa gagaatggat ttgtcctagt tgtaatgaaa ctcacgatag agatataaat
       61 gcaagtataa atatattaaa agaaggatta agactaataa caattcaaaa taaataactt
      121 atgtaagaac cgtaggaact acggggatag cctgtggaga attagtaaga catatgttag
      181 tatgcaaaat tctatgaagc aggaaccctg tgactttagt catgggaggt tcagattgga
      241 aatgtgttgc cacaagatta ttatggatta atagtgattt taggtgttat tcttggagtt
      301 atgggggcat tttacaactg gtttactcta tatgtgcagt ctttatacaa gaagattcct
      361 aaaattggta cctttggaaa actgttgatt ccatttataa tggctggtat tcttgggctt
      421 gttatgcctg atgttctggg gagtggacac aatttagttg aagaacttac aagtcatgaa
      481 tatatttttg gaatggttgt tttgattttt gttatacgtt ttatattttc ggctgttagt
      541 tttgggtcag gtgcaccagg gggaatattt tttccattgc ttgttttagg agcatttata
      601 ggtggaatat ttggtatggt aggtgttaaa gtttttggaa tgaatcccga ttatgtaaat
      661 aactttgtgc ttttggctat ggcaggatat tttacagcta ttgtgcgtgc ccctttgact
      721 ggtatcatat taatttttga aatgacaggt tctgttagtc aaatgctttc actatcagta
      781 atttcaattg tggcatatat tgtggctaca cttatgaagt ctaaacctat ttatgaaagt
      841 cttcttgaga ggttacttga aaaaaatgga gaacctgtac ataaagatag gggcgaaaag
      901 atactagacc agttctctgt tatgtttggc tctcctgttg cgaacaaggc aattcaggat
      961 gtacagtggc ctgaaaattg tcttttggta gcaattcaaa gaggtggaga agaaattatt
     1021 cctagaggta agacaattct tagaccaagt gatgtaattg tgactatgac agatgagaga
     1081 gatagtggtg ctgtgtatga taagatggaa aatttgtgta aagaacatac ggcacatatt
     1141 ttttagggat aatgatgaat gtttaataat gatagaatat ttaatgaaga tttgattaaa
     1201 aaattggtaa tttgaaagag agttaaggaa ttaatataag aaaatgaaaa tgtgatatct
     1261 tagatgtaaa agagtttgaa gaaaataatt gtatatattt gttaatgaga ttatatggac
     1321 taatggtata tttatactgt gctaaaagtt gcactattgt atgaggaatg ggaataaagg
     1381 gtttgaaaaa ataggtggaa gatttttcag atattcttat tgggatattt taattaatat
     1441 attttaattg cgatattttg ggaagaatag aatttattta taaatgaaaa taattaaaag
     1501 gggttaaggt tgtattagcc ccttttgctt atagagtttg gaaagggtat cttgatagta
     1561 gttgtttcat gcttattata ttttattaca tattttaaaa ttgaccttat tactcctaaa
     1621 tcattgttat atcaactttt aaaacacttt caagacaatc gcctattgaa aacaaagtta
     1681 attaaaaacc tacatatcag tttagtattc gtgtagatga ttatataaat ataaaagtat
     1741 aagaaaggtg agtatctgtg gttagttcat ttttaaatga tatctttaga acaattttag
     1801 taagttgtat ttttatagtt attttattag tctttagaat aactttattt aagactttca
     1861 gtaaaaaatt taattactat atatggctta ttgtgattat taagctatca ttaccattta
     1921 tgaattatac ttttatattt aatgagtcaa aatataatgg taatattaat aagataagtt
     1981 taggcaattt taatagtatt tctattgtat atagtactgt tttagtctct gtttggattg
     2041 ctattacgat attttattta gtttatactt tattgaaata tattaagctt aaaaatatga
     2101 taaatgattt gtcttatgat gttgaggatg ataagataaa aaatctttat gaaaatttat
     2161 taaaagagct taagataaat aaaaaaatac ggcttaaata ttcatatgaa gttgaaagtc
     2221 cagtattttt taattcgtgt gtcattttac caccatgtga ttatacatta aaagagttaa
     2281 actggatatt taggcatgag ttgatgcatt ttaagagtaa agacctttat attaagtatt
     2341 tggtgatatt tttaaaatgt gtttattggt ttaatccttt tgtgtatata atggagaagt
     2401 ttatagattt ggattgtgaa ttttattgtg atgaaagagt tttgaagaat tgtacgatag
     2461 aagagaagca ggattatgca ttgacaataa ttagtgcaat gagaaaaggt tcaaatagtt
     2521 caaataaatt tgtggctgga ttacataagg agtcagatat taaaaaaaga gtgtttagta
     2581 tgtttaatga aaagtacaga aatggtattt tgatagcagt tattttatgt ttattatctt
     2641 ctattacata ttttaaaatt gatttaatta ctactaaatc aatattttat ccactttcaa
     2701 aacaaacacc tattgaaaac agaactaatt caaaacctac atatcaggtt aatgtttata
     2761 tagataatta aaaaatacaa agtttaacaa gagattaata taaataattt taataagtat
     2821 ctttcacata tgttaaattt actttaatta tattaaagcc aatgaattat tctttagaag
     2881 ctccaatgcc agtaaataca ggtaaagaaa aaaatactac aattgtagat taaaaatgtt
     2941 ctaatattta aatagataca aaagtgtaag aagggtaaaa atctgttata atacattaaa
     3001 aactaaattt agaaaaattt acataattag aaaaatgatt tgataaaaaa taaagttaaa
     3061 tattaactaa gtaaatttga aaaagaaaaa atataaagta caaatttaaa aggaggtaac
     3121 taatgaaaaa gaagttggaa gatatgactt tagaggagtt atggaacttg tttcctatat
     3181 ttttgactac tcacaaagaa tgttggaaaa attggtttaa agaagaacaa tatagactaa
     3241 ctggaatatt gccaatgcaa aaaattgtta gaataagtca tattggaagt acttctgtga
     3301 gtacgattta tgccaagccc attgttgaca tactgattga gataattcct gattataata
     3361 tgaaagatat taaagatttg attgagtcga atggatatat ttgtatgtct gagagcagta
     3421 gtaggctttc acttaataaa gggtatacag tagatggatt tgaagaacga gtttttcatt
     3481 tgcatataag gtatgtaggt gataatgatg agttgttttt tagagattac ttaattgacc
     3541 acccagatgt tgcaaaggag tatgaaaaac ttaagttgga cctttggaag aagtatgagc
     3601 ataatcgtga tgcttataca gatagtaaac tagattttgt tagggagttt actgaaaagg
     3661 caaaggtgtt gtattctaat agatataatt agaaataggt acaattagat atttatctta
     3721 tatatcgtat tatatttttt aagaaagtaa ttaatagaaa aagggcttgt ttcaaaatgg
     3781 agagataaat ccatttttca ttgttgaaag gataaaaata tatttgattt catgtaaaaa
     3841 agagtgcctc atcaactaaa aagtttattt tgagacacac acatttttac taaggtaaat
     3901 aaaatatcac atttgattaa attttaagtt aatgaatata tgtgtaaata tttaattata
     3961 agttattata attttacata gtatcaaaca atctaatttg tattatataa gataatctaa
     4021 ttttagacta aaataatcta atataaagaa ataaagaaaa ttcactctca gtataagaaa
     4081 tatccaattt tccattgtac ttattaacaa tttctctaat attctcaata ccatatccgt
     4141 gagaattact atctttttta tctgaaataa atagttcttg ttttctattg ataggattta
     4201 ccttgttgtt tgtcaataaa tagctaaaat actccttctc acaacgtgcc tttaatacca
     4261 cttttctatt tgacaaatca ggaattttca aagatgcttc tatagcgtta tctaaagaat
     4321 ttgaaaaaat agtacataaa tctataggtt ctatacccaa gtgattgtct atatctatat
     4381 taaagtgcac atcaacacca ttttcttcta aacttgtatg acgaagattt aaaattgagt
     4441 taagagcttg gtttttgcaa aattgttttc cactaagagt acctatacct atttttaact
     4501 gattaaaata ctttttagct ccagcaatat cttcaatttc taaatacgat tcaatcattt
     4561 gaaagtgatt attcatatca tgtcgcattt tgcgtatttg aatttgttga ttttctagta
     4621 agttatagta tttttctttt aggtgatttg cttgtttttc tatcttcatc tttacatttt
     4681 caatcaatgg ctgtaaaaga agtatcacac cgatatttgc cagaattgct gacaagatga
     4741 ttagataagt gccataaggt aagttgccta agataatatt cttattacta cccataggga
     4801 ttaaattagt aggtggcaga ataatagcaa ttaatattga taaaaatgaa gatatacata
     4861 ccatatcaat aaaaatccat attttatttg ataagtattg ttttatattg accaatctat
     4921 tctttaggaa aatatgtatt aaaaaccaaa ataataattt aattagagca gaaattatct
     4981 ggactattga aagtattaaa atatactctt ttgagtgtat aagttcctca tatatagggt
     5041 tgtttataaa aagaaaatta agcccaatta taataggata aagtatcatg acaactgata
     5101 ttataggaat taatttgctt ttgctacata ttataagtag tataaaatat ccgaatagtg
     5161 taaacaaaat atttatgggg tcggaaagcc atattatcat ttgactaata atagagtagc
     5221 ccaaaatcaa tatgattttg aaaatccaat gattcctaaa gtctataaaa taggaagtca
     5281 acttataaag aaaaaaggct atgaaaatat tgattaatat tagaataaaa tttatgcttg
     5341 tagagattaa agaataagtg cccatttaat atacctttct attaattaag attctggaaa
     5401 ctaagtttta aaaaattaaa tcttaaaaat taaaattctg gaaattagat ttcaaagaat
     5461 tgattttgaa aaataaaatt ctagaaatta agcttcaaaa aattgagttt taaaagattg
     5521 aaattttaaa aattaagttt caaaaaatta aatttgaaaa aaactctaaa aactaagctt
     5581 caaaaaatt
//
LOCUS       DAFAZV010000104         5522 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFAZV010000104 DAFAZV010000000
VERSION     DAFAZV010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5522
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.107"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..461
                     /locus_tag="KOU88_003907"
     CDS             <1..461
                     /locus_tag="KOU88_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213718.1"
                     /translation="NIVADTAKNINLMYKYEWEQHKNSSEYKLEIKRINLEKGLGIKI
                     EKLIPVTWEVSYYTSLNCENSKYGAITATGEKLQYGFVANNHLKFGTKILVDGNLKVV
                     KDRGSNKYFGNSNAIDVFVPRIKGESDYKYYKRVNNMGRHYKEGYIIVEG"
     gene            473..1138
                     /locus_tag="KOU88_003908"
     CDS             473..1138
                     /locus_tag="KOU88_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213719.1"
                     /translation="MKVNGIKIPGIIDVSNVCVYGIKESIISSGYPMQQQIKDMREVN
                     ISEKDLQRACQLGKSKQGSGHDCFSKGIIVQMDLQWSEYMWRQWDRYHHNDYVSSQSK
                     MHRLTKFNIDDMCNKYVDKNTINFLSELIYDYNNFQELKLTASDEIILRNGEKVEATK
                     ETLWKIIISNCPSGLMLTARVTLNYLQIKSMINQRKNHKMEEWRILCDFFKTLPKYKE
                     LMM"
     gene            1161..1331
                     /locus_tag="KOU88_003909"
     CDS             1161..1331
                     /locus_tag="KOU88_003909"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213720.1"
                     /translation="MKLGIPQILVIIIYVMQLGVSLANNGKVKKMKISFGVSTISKLV
                     IFGLLYWGGFFS"
     gene            1451..2296
                     /locus_tag="KOU88_003910"
     CDS             1451..2296
                     /locus_tag="KOU88_003910"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213721.1"
                     /translation="MAKKNVNYNEVFVSGEVLDILAAERVKEGTPQEAIKFKLNVAIS
                     QDKNEIVDYYGSIYTSAGGVNKISQGLETVVNDIVTRAEEGRGEIVRCTCQLDDNTYY
                     SDGEKHEGFRIQGKFCNRQKDAKLPIKAGILWRAYVYLEEIIKIEEGLEVIGIMNKYN
                     DNGFRVRLVIDNTEVIKEFEKLYKVGDVPQLEGDIVTEIIEGTGGFGTGKKDKIIKYL
                     RITGGSGNKISKDNDFGEDGKPNPFYKDNIVAMIDKMEEKENAMKEKDAQKNNINIEE
                     SDLPF"
     gene            2337..2912
                     /locus_tag="KOU88_003911"
     CDS             2337..2912
                     /locus_tag="KOU88_003911"
                     /inference="COORDINATES: protein motif:HMM:NF016302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBK3213722.1"
                     /translation="MEEQIANIESEVKQLKDVIRKMVGDLKENENKDSLIPFRRSENI
                     KDLLVSLVDFQKEVESIEKSSNNPFYNSKYANLDDILITIRPILAKFDLCITQFPISG
                     GNNSVSIKTVLWHSSGQFMESDSVPIKPSKLDIQGYGATETYSKRYALGGLLQLSFCE
                     DDDGNSQVEPPNKKNTSQNIQSTQPKRSGRI"
     gene            2979..3536
                     /locus_tag="KOU88_003912"
     CDS             2979..3536
                     /locus_tag="KOU88_003912"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213723.1"
                     /translation="MGRKITCRYCKEKFLAEDIYSVIHITKTGREEKRNYCCELHYRL
                     EEREKWLWNQILLGIDSIIGYKCIAKNKTKMIKEMLDNGYTREDVYNCILEMKNQIID
                     ALEFRKDIENEYQKLCYIFTILKNNIRDVTIVKKNIQRKEKKETEMDLVDILEETMKI
                     PVARKKRTTTLKDLIKEVGENGIRK"
     gene            3520..5112
                     /locus_tag="KOU88_003913"
     CDS             3520..5112
                     /locus_tag="KOU88_003913"
                     /inference="COORDINATES: protein
                     motif:HMM:NF012974.1,HMM:NF015736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK3213724.1"
                     /translation="MVLENRGNIESLVISVLLQDISIIADYPLSENDFTFPKTKFFYN
                     LIRELSTKYKEIDEVTVSAFVGMSPSLNELYEKYGGWESIQKVRDLGNIHNQKKYIDD
                     LEKSNLIIRLESKGFNIDKEIEVEGVKVKPIDLFPSMTASQVHDFYEMLLADSSINLV
                     GNDVVIEDLHYTSEEILKKKNNEDDNSASFAIALRWQTDTGEERYVQGMPMLSNIIDG
                     VGHSNGIYFIAGHSGTGKTTFTLNMAMGLVESDCKVLIISNEQQSEYYKQILITYISN
                     AIFNCHTMTRRKVKNFDFTIEEEKTFYLANKFIEEKYSIPGKLKFISMYDFNTEKIKK
                     IAKKLSLSEGYDTLILDTFKAEDASSGNSTGEMNEAARDFDKFGKQMRMRIIFPIQLA
                     TYTEGKVSYLTAACISNAKQIKEVGHTITLMRKIIPDELNPEKDRYFLKPYRWKKGRL
                     EGKLQKSYLEIIDSSTKEGKEREFDKNCIDIRKKHILLFVNKTRSGDDDNKILLYEMD
                     GRSGRFIEKAYCDNVFVGQLTY"
     gene            5336..>5522
                     /locus_tag="KOU88_003914"
     CDS             5336..>5522
                     /locus_tag="KOU88_003914"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213725.1"
                     /translation="MSLFDLVMASKNIDFKSSIKFITDIVKCTYCYEPKIGFGTLNLT
                     KSKSILDIEVEILNRIDK"
BASE COUNT         2382 a          509 c         1019 g         1612 t
ORIGIN      
        1 aaaatattgt agcagataca gctaaaaata ttaacttaat gtataaatat gagtgggagc
       61 aacacaaaaa cagttctgaa tataaattag aaatcaagag aattaattta gaaaaggggt
      121 taggaataaa aatagaaaaa ttgattcctg taacatggga agtaagttac tatacttctt
      181 taaactgtga aaatagtaaa tatggagcta ttacagctac aggagaaaaa ttacaatatg
      241 ggtttgtggc caataatcat cttaaatttg gaactaaaat attagttgat ggaaatttaa
      301 aggtggttaa agatagaggt tctaataaat attttggtaa ttctaatgct atagatgtat
      361 ttgtgccaag aataaaaggg gagagtgatt ataagtatta taaaagggtg aacaatatgg
      421 gaagacatta taaagaaggt tatattattg tggaaggtta ggagttgata aattgaaagt
      481 aaatggaata aaaataccag gaattattga tgtatcaaat gtgtgtgttt atggaattaa
      541 agaaagtata atttcgagtg gttatcctat gcagcaacag attaaagata tgagagaagt
      601 aaatatttca gaaaaagatt tacaacgagc atgtcaatta ggcaaatcaa aacaaggttc
      661 aggccatgat tgcttctcta aaggaattat tgtccaaatg gatttgcaat ggtcagaata
      721 tatgtggaga cagtgggata gatatcatca taatgactat gtatctagtc aaagtaaaat
      781 gcacagattg accaaattta atattgatga tatgtgtaat aagtatgttg ataaaaatac
      841 aataaatttc ctgagtgaat tgatttacga ttacaataat tttcaggaat taaagttaac
      901 cgcatctgat gaaatcattc ttagaaatgg agaaaaagtt gaagccacaa aagaaactct
      961 ttggaaaatt ataatatcaa attgtccatc aggattgatg ctaactgcaa gagttacatt
     1021 aaattatcta caaataaaat ctatgataaa tcagagaaaa aatcataaaa tggaagaatg
     1081 gaggatttta tgtgatttct ttaaaacatt accaaaatat aaagaattaa tgatgtaatc
     1141 atattaaaag gagaggttaa atgaaattag gaataccaca aattttagta ataataatat
     1201 acgttatgca attaggagtg tctttagcta ataatggaaa ggtaaaaaaa atgaaaataa
     1261 gttttggagt atctacaatt tcaaagctag taatttttgg tttattgtat tggggaggat
     1321 tttttagtta aaataaataa aattaaaaat aagtattgaa ataataaata gaacatgtta
     1381 ttataagtat atagaaaaat taagaatgat tacaactgaa taaaatacaa aataaaagag
     1441 gaggatattt atggcgaaaa aaaatgtaaa ttacaatgag gtttttgtta gtggggaagt
     1501 gttagatata ttagcagcag aaagagtaaa agaaggaact ccacaagaag caataaagtt
     1561 taaacttaat gttgctatat cacaagataa gaatgaaata gttgattatt atggaagcat
     1621 atacacatct gctggaggag ttaataagat atcacaggga ttagaaacag ttgtgaatga
     1681 tattgtaact agagcagaag agggtagagg agaaatagtt agatgtactt gtcagttaga
     1741 tgataataca tattatagtg atggagaaaa acatgaagga tttagaatac aaggtaaatt
     1801 ttgtaacaga caaaaagatg caaaactacc tataaaggca ggtatattat ggagggcata
     1861 tgtatacttg gaggaaataa taaaaataga agaaggatta gaagtaatag gaataatgaa
     1921 taaatacaat gataatggat ttagagttag acttgtaatt gataatacag aagtaataaa
     1981 agaatttgaa aagctatata aagtgggaga tgtaccacaa ttagaaggag atatagtaac
     2041 tgagataata gaaggaactg gtggatttgg tacagggaaa aaagataaaa taataaaata
     2101 tcttagaata actggaggtt caggaaataa gatatcaaaa gacaatgatt ttggtgaaga
     2161 tgggaagcct aatccattct ataaggataa tatagtagcc atgatagata aaatggaaga
     2221 aaaagaaaat gccatgaaag aaaaagatgc acaaaagaat aacataaata ttgaagaatc
     2281 agatttacca ttttaattaa tatttataaa ctaaataaaa tttaaaggag agttttatgg
     2341 aagaacaaat agctaacata gagagtgaag taaaacaatt aaaagatgta ataagaaaaa
     2401 tggttggaga tttaaaagaa aatgagaata aagattcatt aataccattt cgcagaagtg
     2461 aaaatataaa agatttatta gtaagtttag ttgattttca aaaagaggta gaaagtattg
     2521 aaaagagttc taataatcca ttttataata gcaaatatgc aaatttagat gatattctaa
     2581 taacaataag accaatatta gcaaaatttg atttatgtat aactcaattt cccatttctg
     2641 gtggaaacaa ttcagtatca attaaaactg tattatggca ttctagtggt cagtttatgg
     2701 agtccgatag tgtacctata aaaccgagta aattagatat tcaaggatat ggagcaacag
     2761 aaacatatag taagcgttat gcactaggtg gcttacttca attatcattt tgcgaggatg
     2821 atgatggcaa ttctcaagtt gaacctccta ataaaaaaaa tacatctcaa aatattcaaa
     2881 gtacccaacc taagcgttct ggaagaatat agaataattt aaaaggtcgc tcaattaggg
     2941 cgacttttaa acatcaacaa taagaaggag gagaattatt gggaagaaaa ataacttgta
     3001 gatactgtaa agaaaaattt ctagctgaag atatatactc agtgattcat attactaaaa
     3061 cgggtagaga agaaaaacga aattattgtt gtgaattaca ctatagatta gaagaaagag
     3121 agaaatggct atggaatcaa attttattag gaatagatag tattattggt tacaaatgta
     3181 tcgcaaaaaa taagactaaa atgataaaag agatgttaga taacggttat acaagagaag
     3241 atgtttataa ttgtatttta gaaatgaaaa atcaaataat tgacgcttta gagtttagaa
     3301 aagatataga aaatgaatat caaaaactat gctatatatt tacaatatta aaaaataaca
     3361 taagagatgt tacaattgta aagaaaaata tacaaagaaa agagaaaaaa gaaactgaga
     3421 tggatttagt agacatactt gaagaaacaa tgaaaattcc agtagcgaga aaaaaaagaa
     3481 caacaacctt aaaggattta ataaaggagg ttggagaaaa tggtattaga aaatagaggg
     3541 aatattgaaa gccttgtgat atcggttctg ttgcaagata taagtataat tgctgactat
     3601 cctctatctg aaaatgactt tacttttccg aaaactaaat ttttttacaa tctcataaga
     3661 gaattaagta caaaatataa agagatagat gaagtgacgg tatcagcatt tgtaggaatg
     3721 tctccttcat taaatgaatt atatgaaaaa tatggtggtt gggaaagcat acaaaaagtt
     3781 agagatttag gaaatataca caatcaaaaa aaatatatag atgatttaga aaaatctaat
     3841 cttataataa ggctagaaag taaaggcttt aatatagata aggaaattga agtggaaggt
     3901 gtaaaagtaa aaccaataga cttatttcct tctatgactg catctcaagt tcatgatttt
     3961 tatgaaatgt tattagcaga tagtagtatt aatttagttg gaaatgatgt tgttatagaa
     4021 gacttgcatt atacttcaga agaaatatta aaaaagaaaa ataatgaaga tgataactca
     4081 gctagttttg caatagcttt aagatggcaa actgatactg gagaagaaag atatgttcag
     4141 ggtatgccta tgttgagtaa cataatagat ggagtagggc actcaaatgg tatatatttt
     4201 atagcaggtc atagtggcac tggaaaaaca acttttactt taaatatggc tatggggcta
     4261 gtagaatctg attgtaaagt cttgataata agtaacgaac aacaaagtga atactacaaa
     4321 cagatattaa taacatatat atcaaatgct atatttaatt gtcatacaat gactaggaga
     4381 aaagttaaaa attttgattt tacaattgaa gaagaaaaaa ctttctactt agcaaataag
     4441 tttattgaag agaaatattc aataccagga aaacttaaat ttatatcaat gtatgatttt
     4501 aacactgaaa aaataaaaaa aatagccaaa aaattaagtt taagtgaagg ctatgatact
     4561 ttgatacttg atactttcaa agctgaagat gcctcatcag gaaattctac aggtgaaatg
     4621 aatgaagcag ctagagattt tgataagttt ggaaaacaaa tgaggatgag gataattttt
     4681 cctatacaat tagcaactta tactgaaggg aaagtcagtt atttgactgc tgcttgtata
     4741 tcaaatgcaa aacaaattaa agaggtgggg catacaataa cattgatgag aaaaataata
     4801 ccagatgaac taaatcccga aaaagataga tattttttaa aaccgtacag atggaaaaaa
     4861 ggtaggttag aagggaagct tcaaaagtca tatttagaga ttatagatag ttccacaaaa
     4921 gaaggaaaag aaagagagtt tgacaaaaat tgtatagata ttagaaaaaa acacatttta
     4981 ttatttgtaa ataaaactag gtctggtgat gacgataata aaatattatt gtatgaaatg
     5041 gatggaaggt caggaagatt tatagaaaaa gcatattgtg ataacgtatt tgttgggcaa
     5101 ttaacctatt aggaggtgat tatatataga tgcgaaagag cttttaaaaa gcataactga
     5161 agaagatata ataaaaatac ttagtgaact tggaagtgat ttatctgaaa gaagtaatga
     5221 caaagaatta atatttaaaa caatatgtca caataatcca aatgatgagt gtagctataa
     5281 attatattat cataaagatt caaagttgtt tacttgtttt actaactgtg gaaatatgtc
     5341 tttatttgat ttggttatgg catctaaaaa tatagatttt aaaagttcca ttaaattcat
     5401 cacagatata gtgaaatgca catattgtta tgaaccaaaa ataggttttg gtacacttaa
     5461 tctaactaaa agcaaatcca tattagatat agaagttgaa atattaaatc gtatagataa
     5521 gc
//
LOCUS       DAFAZV010000105         5506 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFAZV010000105 DAFAZV010000000
VERSION     DAFAZV010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5506
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.108"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..226
                     /locus_tag="KOU88_003915"
     CDS             <1..226
                     /locus_tag="KOU88_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213726.1"
                     /translation="EKVISILSSRFEELKKNSGLDNLEKSLKAITRGDTKIEYNALTL
                     QTAENSISSSSFLTDTDKKFLSPFCIVSMY"
     gene            238..585
                     /locus_tag="KOU88_003916"
     CDS             238..585
                     /locus_tag="KOU88_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213727.1"
                     /translation="MTEADILEMTYLDKMTIIRKLKGWNEETCSNDFSNVVIAENIPC
                     AISRKEEAIVNGDIGSIVVNRKLFCRPEVDIKIGDTINTTYNHGEEAVFKVSKANIYP
                     SHMEIPITELERI"
     gene            585..941
                     /locus_tag="KOU88_003917"
     CDS             585..941
                     /locus_tag="KOU88_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK3213728.1"
                     /translation="MGIDNLGVFEALALDLGLNASNFNRKIKKFTKETGQELAENIRD
                     ETPVKTEKLKKGWEEKQPEYDTYIVKNEVDYATLVNNGHSTKNGGIVPGSFMVEKGIE
                     RTKENMTSAKANLFDW"
     gene            950..1399
                     /locus_tag="KOU88_003918"
     CDS             950..1399
                     /locus_tag="KOU88_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213729.1"
                     /translation="MLTNRDIIIAVNKRIENEFRYIDIFINEDNIQGFEEACFFVQLL
                     PVSNNIANKVLDTKKIFIDIEYYQKARKNKLNLYDIQSRLEKIFNRNIRVKDRSLIIE
                     NISPSIAKDPVGYKLTFLMTVSYFEEVYFENETFEIMESVDLEIGSD"
     gene            1400..2455
                     /locus_tag="KOU88_003919"
     CDS             1400..2455
                     /locus_tag="KOU88_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HBK3213730.1"
                     /translation="MGLPEINISFIQAGKTFVKRSGGIVALILKDTKNIGLVEIKEIE
                     DIPENYSAANLDYIKMAMKGNVYPPNKVLVYTLDTDESIDDALDFLETCEFNYLCMPD
                     ETEQDLPKIKTWIKKMREDNKIKVKAITASNSADYEGIINFTATDIEVEGKKYTSNEF
                     LPRIAGFIAGTPSTQSVTYAEIPEVTNIPKLTRAEANTRINNGELILIKESGAIVIAR
                     GVTSFTTITDSKGDIFKKIKLVDTLDQIHNDIKKIIVKNYIGKTQNTYDNKCLLIVAI
                     QLYLQELEKDGLIDEGSTVEINLDAQRAWLKKQNIDISNMEEQQIKEYNTDTLVFLKA
                     RIKLIDAMEDVYLDISM"
     gene            2471..2911
                     /locus_tag="KOU88_003920"
     CDS             2471..2911
                     /locus_tag="KOU88_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBK3213731.1"
                     /translation="MKAKIDAKRIISGTFGECWLDNKQLTSTKGMEAKVDIDKEEIKL
                     CGQIMTTYKMIGATGKGSITLYKISTLFGEYVEKMLNEGKEFKVTIISKLQDPDSYGS
                     ERIALYGCMFDDLTLADWEAAKVGEIEVPFTFEGFEYLDKIKEK"
     gene            2926..3342
                     /locus_tag="KOU88_003921"
     CDS             2926..3342
                     /locus_tag="KOU88_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213732.1"
                     /translation="MNTVEKLLNMDAGKLKMPSSAFELYCKKLDDTLEIECKAIDPER
                     FDEIRMNSMDVNSGDVENINIYELKVNTILESCSIFSNMELVKKFSAITPKELIKKLL
                     LSGEIDKLYEEVNKVNGIDAEGDKKRQKERAKDIKN"
     gene            3369..3518
                     /locus_tag="KOU88_003922"
     CDS             3369..3518
                     /locus_tag="KOU88_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213733.1"
                     /translation="MYLLFKYKGIMPSVSYRILRGEKEIVSVFMDQELDEREEEIKSG
                     AGRLF"
     gene            3522..>5506
                     /locus_tag="KOU88_003923"
     CDS             3522..>5506
                     /locus_tag="KOU88_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBK3213734.1"
                     /translation="MSSNTKVLQAIIKMRDEASSTLKRVAANTRALHDSSSQASRTLN
                     NVQSNLKSVGTSALKAGGLITAGVGGAFAAATKVGTEFESAMSQVKATFGNSLKPGDF
                     EALSKAARDAGKATTKTAADSANALQYMGLAGWDVQKSMHALMPVLNLSEAASMDLGL
                     ASDLVTDSMSSMCLEVDKVSKSGKVLAGAGLSEYLDKVANASTKSNTSIQQLMEAFNV
                     AGGTFSNLKVPLSEATAIMGILANRGVKGTDAGHALNSIMVNLTTGAGQAGKAMKKLG
                     VSAFDNQGKFKGMSNVLKEVANKTKDMTDKQKNYYLAAIGGKTQLKTLQKLLDGVGNE
                     YDSLKKKIDNSKGALKTMSDVMKDNTKGGLATLKSALEETGITIYYQLKPAIASVVDN
                     LTKMTVWFNNLSEPIKRVITNVMLSVGAFGVLLLTIGAVSLIVSKAIGIFGFFVPIIL
                     RAKVAFRAFVIGMKPLSAVFLAVMGPIGWTITAVIALSVAFTIAYAKSEVFRNKVNSL
                     VKSFTEFAKPIVNFCMPALKQLGEKFKELLSAFGPLFASILNLGSVIMKVLGPVLIGV
                     IGFHIAKLVLILSTLATAFKAVVDTITNVLNGLASILNGVFNLIIGIVTGDSKKMMNG
                     VKQIFDGGVKIIKSIWKGFIDFVTAPIQAIADIADSL"
BASE COUNT         2180 a          630 c         1033 g         1663 t
ORIGIN      
        1 agaaaaagta atatcaatat tatcttcaag atttgaagaa cttaagaaaa atagtggact
       61 tgataatcta gaaaaaagct taaaagctat aactagaggt gacactaaga tagaatataa
      121 tgctttaaca ttacaaactg ctgaaaatag catcagttca tcatcttttt taactgatac
      181 tgataaaaaa tttctaagcc cattttgtat tgttagtatg tactaagggg tgattaaatg
      241 actgaagcag atatattaga aatgacatac cttgataaaa tgactataat tagaaaatta
      301 aaaggctgga atgaagaaac atgttctaat gattttagta atgttgttat agctgaaaat
      361 atcccatgtg caatttctag aaaagaagaa gccattgtaa atggtgatat tggatctata
      421 gttgtaaata gaaagttatt ttgtagacca gaagtagata taaaaatagg tgatactata
      481 aatacaacct ataatcatgg agaagaagct gtatttaagg tttctaaggc aaatatatat
      541 ccaagccata tggaaatacc tattacagaa ttggagagga tataatggga atagataatt
      601 taggagtctt tgaagcatta gccttagatt taggtctaaa tgcatcaaac tttaatagaa
      661 aaatcaagaa gtttacaaaa gaaactgggc aagaactagc agaaaatata agagatgaaa
      721 ctcctgtaaa aactgaaaag ttaaaaaagg gatgggaaga aaagcaacca gaatatgata
      781 cttatattgt taaaaatgaa gttgattatg ctactttagt aaataatggc cattcaacta
      841 aaaatggtgg cattgtccct ggttctttta tggttgaaaa gggaattgaa agaacaaaag
      901 aaaatatgac aagtgcaaaa gcaaatttat ttgattggta ggtgattagt tgcttacaaa
      961 cagagacatt ataatagcag ttaataaaag aatcgaaaat gagtttagat atatagatat
     1021 ttttattaat gaggataata tacaaggctt tgaggaggct tgtttttttg tgcaactttt
     1081 acctgtttct aataatattg caaataaagt tttagatact aaaaagatat tcatagatat
     1141 tgaatattac caaaaggcta gaaaaaataa attaaatcta tacgacatac aaagtagatt
     1201 agaaaaaata tttaacagaa acattagagt taaagataga agtttaatca ttgagaatat
     1261 atctccatca atcgcaaaag atcctgtagg atataaacta acttttctaa tgactgtatc
     1321 ttattttgaa gaagtctatt ttgaaaatga aacatttgaa attatggaaa gtgtagattt
     1381 agagatagga agtgattaaa tgggtttacc agaaattaat atttctttta tccaagcagg
     1441 aaaaactttt gttaaacgct ctggtggtat tgtagcgctt attttaaaag atacaaaaaa
     1501 tatagggtta gttgagataa aagaaataga ggatattcca gaaaattatt ctgctgctaa
     1561 tttagattat ataaaaatgg ctatgaaggg aaatgtatat cctccaaata aagtattagt
     1621 ttatacatta gatacagatg aatcaataga tgatgcacta gattttcttg aaacttgtga
     1681 gtttaattat ctttgtatgc cagatgagac agaacaagat ttgcctaaaa tcaaaacgtg
     1741 gattaagaaa atgagagaag ataataaaat aaaggttaaa gctattactg caagtaattc
     1801 agcggattat gaaggtataa taaactttac agcaactgat attgaagttg aaggtaaaaa
     1861 atacacttca aatgaatttc tgccaagaat agcaggtttt attgcaggaa ctccatcaac
     1921 tcaatctgta acatatgcag aaataccaga agttactaat atacctaagc taacaagagc
     1981 tgaagcaaat acaaggataa ataatggaga gctaatttta ataaaagaaa gtggagctat
     2041 agtaatcgct agaggagtta catcctttac aacaattact gattcaaaag gtgatatatt
     2101 caaaaagatt aagttggttg atacactaga tcaaattcat aacgatatta aaaaaataat
     2161 tgtaaaaaat tatataggaa aaacccaaaa cacttatgat aataagtgtt tacttattgt
     2221 tgcaatacaa ttatatcttc aagaattaga aaaagatggt ttaattgatg aaggttcaac
     2281 tgtagaaatt aatttagatg ctcaaagagc atggctaaaa aaacaaaata tagatatatc
     2341 taatatggaa gaacaacaga taaaagaata caatactgac actcttgtat ttttaaaagc
     2401 aagaattaaa ttaatagatg caatggaaga tgtatattta gacatctcta tgtagtttgg
     2461 aggttaaaat ttgaaagcta aaatagatgc aaaaagaata atatctggta cttttggaga
     2521 gtgttggcta gataataagc aacttacatc aacaaaaggg atggaggcca aggttgatat
     2581 agataaagaa gaaataaaat tatgtggtca aataatgacc acatataaaa tgattggtgc
     2641 aactggaaaa ggatctataa ctctttataa gataagtacc ttatttggcg agtatgtcga
     2701 aaaaatgtta aatgaaggta aagaatttaa agtaactata ataagtaaat tgcaagaccc
     2761 agattcatat ggttctgaga gaattgcact ttatggatgt atgtttgacg acttaacttt
     2821 ggctgattgg gaagctgcga aagttggaga aatagaagtt ccattcacat ttgaaggctt
     2881 tgaatactta gataaaataa aagaaaaata ggaggatttt attatatgaa cacagtagaa
     2941 aaattattaa atatggatgc aggtaaatta aaaatgccat ctagcgcatt tgaattatat
     3001 tgtaaaaaac tagatgatac tttagaaata gagtgcaagg ctattgatcc agaacgtttt
     3061 gacgaaataa gaatgaactc tatggacgtt aatagtggag atgtagaaaa cattaacata
     3121 tatgaactta aagtaaatac aatattagaa tcatgttcta tatttagcaa tatggaatta
     3181 gttaaaaaat ttagtgcaat tacacctaaa gaattaatta aaaagctatt acttagtggt
     3241 gaaatagata aattatacga ggaggttaat aaagtaaatg gaatagatgc agagggcgat
     3301 aaaaaaagac aaaaagaaag agctaaagat ataaaaaact aattaaaacg gatggagaag
     3361 ttaacttgat gtacttatta tttaagtata aaggtataat gccatccgtt tcttatcgta
     3421 tactaagagg cgaaaaagaa attgttagtg tttttatgga tcaagaatta gatgaaagag
     3481 aagaagaaat aaaatctggt gctgggaggt tgttttagta tatgagttct aatacaaaag
     3541 tcctacaagc aataataaaa atgagagatg aagcaagttc aacattaaaa agagtagcag
     3601 caaatactag agctctacat gattcatctt ctcaagcatc aagaacatta aataatgttc
     3661 aaagtaattt aaaaagcgtt ggaactagtg ctttaaaagc aggaggtctt atcactgctg
     3721 gagttggtgg cgcatttgca gctgcaacta aagttggaac agaatttgaa agcgctatgt
     3781 cgcaagttaa ggctacattt ggaaattcct taaaaccagg agattttgaa gctctgtcta
     3841 aggctgctag agatgccgga aaagctacaa ctaaaactgc tgctgattct gctaatgcac
     3901 ttcaatacat ggggcttgct ggatgggatg ttcaaaagtc aatgcatgcc ttaatgccag
     3961 tgcttaattt atcagaagca gcctctatgg atcttggtct agcatcagat ttagtaactg
     4021 atagcatgag ttctatgtgc ttagaagttg ataaggtcag taaaagtgga aaagtattag
     4081 ccggtgcagg tttaagtgag tatttagata aagttgcaaa tgcatctact aaatcaaata
     4141 caagtataca acagttgatg gaagcgttta atgttgcagg tggtacattt agcaatttaa
     4201 aagttccgct ttcagaagca actgctatca tgggaatact tgcaaacaga ggagttaagg
     4261 gtacagatgc aggccatgct ttaaactcta tcatggtaaa tcttacaaca ggtgcaggcc
     4321 aagcaggtaa ggcaatgaaa aagctaggcg taagtgcatt tgataatcaa ggtaaattta
     4381 aaggtatgtc aaatgtactt aaagaagttg caaataaaac aaaagatatg actgataaac
     4441 agaaaaatta ttacttagca gctataggag gaaaaactca attaaaaacg ttacaaaagt
     4501 tacttgatgg tgtgggaaat gaatatgata gtttaaagaa aaaaatagat aattcaaaag
     4561 gtgctttaaa aacaatgtct gatgtaatga aggataatac taagggtgga cttgcaacct
     4621 taaaatcagc ccttgaagaa actggaatta ctatttacta tcaactaaag ccagcaatag
     4681 catctgtagt tgataattta actaaaatga ctgtttggtt taataatcta agtgaaccaa
     4741 taaaaagagt cataactaat gtaatgcttt cagttggagc atttggagta cttttattaa
     4801 ctataggggc tgtgtcttta attgtttcaa aagctatagg tatatttggc ttttttgttc
     4861 caataatatt aagagcaaaa gttgctttca gagcttttgt aattggtatg aaaccattaa
     4921 gtgcagtatt tttagctgta atgggtccta taggatggac tataacagct gtaattgcat
     4981 tgtcagtagc atttaccatt gcttatgcta aatctgaagt atttagaaat aaggttaatt
     5041 cattagtaaa atcatttaca gaatttgcaa aacctatagt aaatttttgt atgcctgcac
     5101 ttaaacaatt aggggaaaaa tttaaagagt tgttatcagc atttggtcca ctatttgcgt
     5161 ctattttaaa cttaggaagt gtaataatga aggtactagg acctgtttta attggcgtaa
     5221 taggttttca tatagcaaaa ttagttttga ttttatctac tctggcaact gcctttaaag
     5281 ctgtagttga tactataact aatgtattaa atggtctagc atctatttta aatggagtat
     5341 ttaatttaat tataggtatt gtcacaggcg atagtaaaaa gatgatgaat ggagttaaac
     5401 aaatatttga tggtggagta aaaattataa aatcaatttg gaaaggtttc atagattttg
     5461 taactgctcc tatacaagct atagctgata tagctgacag cttatt
//
LOCUS       DAFAZV010000106         5498 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFAZV010000106 DAFAZV010000000
VERSION     DAFAZV010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5498
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.109"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            23..463
                     /locus_tag="KOU88_003924"
     CDS             23..463
                     /locus_tag="KOU88_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213735.1"
                     /translation="MGDLNAFLSQNAIKVENRKYVASERFIGEDGKAIEWELKAIDSD
                     RDRQLRKDSTIRVPILNKKGKATGQYTSETDFNTYTLKLCVETIVFPDLHDAELQNSY
                     GVMGAEELLTTMLTPGEYTDLSSEVGEVNGFDRTFEDKVEEAKN"
     gene            463..657
                     /locus_tag="KOU88_003925"
     CDS             463..657
                     /locus_tag="KOU88_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015390885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213736.1"
                     /translation="MYEGDYDSNIAHYCLHKFKWKPHEYMDLPVDEKAFVAASIDIKV
                     EEEKEEAKKADKDAKRGRRR"
     gene            725..1516
                     /locus_tag="KOU88_003926"
     CDS             725..1516
                     /locus_tag="KOU88_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBK3213737.1"
                     /translation="MGLFSKKNKKPCCICGSEKGLMPSIEGENFCTACNCKYIDFSEN
                     ILKVTSIMKMMSNSEGMKKFIEVEKKNLKLLEKFTETKSINSSISFDEEQNLLKISYK
                     NRNQILVEKIIKFDDILEFELLEDGETIVKGGLGRAITGGVLFGGTGAVVGGITGKKT
                     SRKVVEIFKIKITVKDINNPIEYINLINSKVKTNSSIYQKAFSDAQEILSILSIITKY
                     NVMEDKKKSISSSTADEILKYKNLLDMEAITQEEFDAKKKELLNL"
     gene            1583..3925
                     /locus_tag="KOU88_003927"
     CDS             1583..3925
                     /locus_tag="KOU88_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBK3213738.1"
                     /translation="MATIQTSIRIFDGMTPAFRHMNNAMNIVLSSFEQLQRTSSNAID
                     ANSIRTAREELARAEAGFDRLEQQIRESDNQQRRLNEDINKGASSTDRLVGSAKKLAA
                     TYLGIRTLGGLGNLSDQMTSTNARLSMINDGQLSDGGLNKMIFQSAERSRASYLDTAK
                     IVSRIGMNAGKAFSSTKEIVGFAEQLNKKFVIAGASTEEMNSALLQLTQGLSSGVLRG
                     EELNAVFESAPNIIQSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAAAEQTNAEFE
                     KMPYTLGQIFTSVKNNAVMVFGAIQKKIEDTVSSRGFRTFITDVKDSLYVLGAVGFNV
                     FSGFINLLSSPAFQNFFNVMIVGTSLVVQGLGWIITQALSVANVFSRNWSIISPIILG
                     VVSAISTYIIALGIMQAVTIAGTVANWMSWTSEVIRQRGILGTARALAIGKAEQWGFN
                     AAIYACPIFWIVLGIIAVISAVFILVAVYNHFAGTSISAISLIVGAWYWLCAVVYNVI
                     VGIVNAINICVVEIANIFRTGLYAVQCFFIDMANAGLKAGVNLDKAFDKFATNLANGI
                     IKAVNIAVKGLNWLVQQINKIPGIDLPQMKEFQKVNTVIGTKTTFKPIQKPPEPKAWK
                     PELVEYKNLKSEFIKGYDVGHQLQNKFKDTFDISKIAEKAKKDLGLDDLWDKKYGLGD
                     GLGSAGLNSPLSDAAKGAKDTAGNTAKMAKTMDKSQEDLKYLRDIAEQETINRFTGVN
                     IKIDMNNTNNISKDADVDGIVNVLTEKLNDAMVVSAEGIV"
     gene            3941..4642
                     /locus_tag="KOU88_003928"
     CDS             3941..4642
                     /locus_tag="KOU88_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK3213739.1"
                     /translation="MAYDFYLDGVQLPIPPPKLEIKVTNKNKTVDLINTGEVNILKKE
                     GLSEISFEAEFTHNKLPFYRGTFRDVQFFLSKLELLKTDCKPFQFIVSREMGGKVLFN
                     TNMKVSLEEYNIVEDADNGSDVKVAIKLKQYRDYSTKKLVPATPEKTNYGRTPTPVMK
                     PKEFRPDSSNKPNGKTYTVKAGDSLWSICQKQLGNGSLYKKVYELNKTMMDKANKGKK
                     VPKYTIYKGQVLKLG"
     gene            4635..>5498
                     /locus_tag="KOU88_003929"
     CDS             4635..>5498
                     /locus_tag="KOU88_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase"
                     /protein_id="HBK3213740.1"
                     /translation="MADELVLANDRDVRLVIAHWEDFYEPVVLDGITWEIERRGTPSK
                     LEFTIVMDDILEFCEGNSVRLYYKGIGIFYGYIFQKKRDKENHIKIVAYDQLRYFKNK
                     DTYVYSNKTASELVKMLAKDFNLKYNVIEDTKYKISRIEENKTLFDMILTALDDTLRE
                     KKEMYVLYDDFGRLTLKNVASMKLDTVMNNDVIEDFDYNSSIDSDTYTKIKLVRDNEE
                     TGKRDVYIAQDSTHMRSWGILQMFDTVDKNMSEAEIKQKCDILLKLYNKKTKSLSLKN
                     ALGDIRVRAGCL"
BASE COUNT         2163 a          641 c         1109 g         1585 t
ORIGIN      
        1 gtgatggagg tagaataaga atatgggaga tttaaacgct tttttaagtc aaaatgcaat
       61 aaaagtagag aatagaaagt atgtggcaag tgaaaggttt ataggagaag atggaaaagc
      121 aatcgaatgg gaacttaaag caatagattc agatagggac agacaattaa gaaaagattc
      181 aactataaga gtacctatat taaataaaaa agggaaagct acaggacaat acactagtga
      241 aacagatttt aatacttaca ctttgaaatt atgtgtggaa actatagtat ttccggattt
      301 acatgatgca gaattacaaa atagttatgg tgtaatgggt gcagaggagt tattaacaac
      361 aatgttgact cctggcgaat atacagacct ttcaagtgag gtaggagagg taaatggttt
      421 tgatagaact tttgaagata aagtagaaga agcaaaaaac taatttatga aggtgattat
      481 gattctaata tagctcatta ttgccttcat aagtttaaat ggaaaccgca tgaatatatg
      541 gatttaccag ttgatgaaaa agcatttgtt gctgcttcta tagatatcaa agtagaagaa
      601 gaaaaagaag aagctaaaaa agctgacaaa gatgcaaaga gaggtagaag aagataatct
      661 ctggtgtaaa aattttacta atatagtata atatatttaa aaattgtact gggggattaa
      721 ataaatggga ttgtttagta aaaagaataa gaaaccttgt tgtatttgcg gaagcgaaaa
      781 aggacttatg ccatctatag aaggtgaaaa tttttgtaca gcttgtaatt gcaagtacat
      841 agatttctct gaaaatattt taaaagtaac tagtattatg aaaatgatgt caaactcaga
      901 aggaatgaaa aagtttatag aagttgaaaa gaaaaattta aaattgttag agaagttcac
      961 cgagacaaaa agtataaatt cttcaatttc ttttgatgaa gagcaaaatc ttttaaaaat
     1021 atcatataaa aatagaaatc aaatattagt agagaaaata ataaaatttg atgatatatt
     1081 agaatttgaa cttttggaag atggagaaac tatagttaaa ggtggtttag gtcgtgctat
     1141 aactggagga gtcttattcg gaggtacagg ggctgtagtt ggaggaatta caggtaaaaa
     1201 aacaagtaga aaagttgtag aaatatttaa aataaaaata actgtaaagg acataaataa
     1261 tccaattgaa tatataaatt taattaatag taaagtaaaa acaaactctt ctatttatca
     1321 gaaagctttt tctgatgctc aagaaatatt atcaatacta tcaataatta caaaatataa
     1381 tgtaatggaa gacaaaaaaa agtctatatc tagttctaca gctgatgaaa tattaaaata
     1441 taagaatttg ttagatatgg aagctattac acaagaagaa tttgatgcta agaaaaaaga
     1501 attgctaaat ttataatata taagcactta cttaaaaata agtaagtgct tatattatgt
     1561 taaaaaagaa aggaggttaa aaatggcaac tatacaaaca tctatccgaa ttttcgacgg
     1621 aatgacacct gcttttagac acatgaataa tgctatgaat attgtattaa gttcattcga
     1681 gcaattacaa agaacatcta gcaatgctat agatgctaat agtattagaa cagctagaga
     1741 agaactagca cgtgcagaag ctggctttga tagactagaa caacaaataa gagaatcaga
     1801 taatcaacag cgaaggctta atgaggatat aaataagggt gcaagttcta cagatagatt
     1861 agttggaagt gcaaagaagc tagcagcaac ctacttaggt ataagaacgt taggaggtct
     1921 aggaaattta agcgaccaga tgacaagtac taacgcgaga cttagtatga taaatgatgg
     1981 tcaactctca gatggaggat taaataagat gattttccaa tctgctgaaa ggtctcgtgc
     2041 atcttactta gatactgcaa aaatagtttc acgaataggc atgaacgcag gtaaggcgtt
     2101 tagcagtaca aaagaaattg taggttttgc agagcaacta aataaaaagt tcgtaattgc
     2161 tggagcaagt actgaggaaa tgaattcggc attgttacag ctaacccaag ggttgagttc
     2221 tggtgtatta agaggtgagg aactgaatgc tgtgtttgag tcagcaccta acatcatcca
     2281 atcgattgca gattatttgg acgtggacat aggaaaaata agaggaatgg catcagaggg
     2341 aatgttaaca gcagatattg taaaaaactc attacttgca gcagcagagc agactaatgc
     2401 agagttcgag aagatgcctt atacgctagg tcaaatcttt actagtgtaa aaaataatgc
     2461 agttatggta tttggagcta tacagaagaa aattgaggac acagtttcaa gcaggggatt
     2521 tcgaactttc ataactgatg ttaaagactc attatatgta cttggagcag ttgggtttaa
     2581 tgtatttagt ggatttatta atttactgag tagtccagct tttcagaatt tttttaatgt
     2641 gatgattgtt ggaactagtt tagttgtaca agggctaggt tggataataa cacaagcact
     2701 tagtgttgct aatgtatttt cgcgaaattg gagtataatt tcacctataa ttttaggtgt
     2761 agtttcagct attagtacct atataatagc tcttggtatt atgcaagcag ttactatagc
     2821 tggaactgta gcaaattgga tgtcgtggac atctgaagtt attagacaaa gaggaatttt
     2881 aggaacagct agagctttag cgataggcaa agctgaacaa tggggattta atgctgctat
     2941 atatgcatgt cccatttttt ggatagtttt aggtataatt gcagtaatat ctgctgtatt
     3001 tatattagta gcagtttaca atcactttgc aggcacaagt atttctgcaa tcagtcttat
     3061 agttggagct tggtattggt tatgtgcagt tgtttacaac gtaattgtag ggatagtaaa
     3121 tgctataaat atctgtgtgg ttgaaatagc aaatatcttt agaactggat tatatgcagt
     3181 gcaatgtttc tttattgata tggctaatgc aggactcaag gcaggtgtta atttagacaa
     3241 agcttttgat aaatttgcta ccaatctagc aaatggtatt ataaaagctg ttaatatagc
     3301 tgtaaaagga ttgaattggt tagtacaaca gattaataaa attccaggaa ttgatttacc
     3361 acaaatgaaa gaatttcaaa aagtaaatac tgtaattggt acaaaaacaa catttaaacc
     3421 cattcaaaaa ccgcctgagc ctaaagcatg gaaaccagaa ttagtagagt acaaaaattt
     3481 aaagtcagaa tttataaaag gatatgacgt aggacatcaa ttacaaaaca aatttaaaga
     3541 tacttttgac attagcaaga tagccgaaaa agcaaaaaaa gatttaggtc tagatgacct
     3601 ttgggataaa aaatacggac ttggtgatgg attgggttca gctggattaa attcaccttt
     3661 gagtgacgca gcaaaaggag caaaggacac agcaggcaat actgcaaaaa tggcaaagac
     3721 tatggataaa agtcaagagg acttaaaata tcttagagac attgcagagc aagaaacaat
     3781 aaaccgattc acaggggtaa atataaaaat tgacatgaac aacactaata acataagtaa
     3841 agatgcagat gtggatggta tagttaatgt actaacagaa aaactgaatg atgctatggt
     3901 tgtatctgct gagggaatag tttagagagg aggtgtaatc gtggcttatg atttttattt
     3961 agatggagta caattaccaa tacctccacc aaagttagag attaaagtta caaataaaaa
     4021 taagacagtt gatttgataa atactggaga agtaaacata ttaaaaaaag aagggctatc
     4081 tgaaataagt tttgaagcag agtttacaca taataaatta cctttttatc gtggaacttt
     4141 tagggatgtt caattctttt taagtaagct agaattacta aaaactgatt gtaagccatt
     4201 tcaatttatt gtatcgaggg aaatgggtgg aaaagtacta tttaacacta atatgaaagt
     4261 gtcattagaa gaatataaca tagtagaaga tgcagacaat ggttcagatg ttaaagttgc
     4321 aataaagtta aagcaatata gagattactc aactaaaaaa ttagttcctg caactcctga
     4381 aaagacaaac tatggtagga ctcccactcc agtcatgaaa ccaaaagaat ttagaccaga
     4441 ttcatccaat aagccaaatg gtaaaacata tacagtaaaa gcaggggata gcctttggtc
     4501 aatctgccag aagcaacttg gtaatggttc attatataag aaagtatatg agttaaataa
     4561 aacaatgatg gataaagcta acaagggtaa aaaagtacct aaatacacaa tttacaaagg
     4621 gcaggtgtta aaacttggct gatgaattag ttctggcaaa tgatagggat gtaaggctag
     4681 ttattgcaca ttgggaagat ttctacgaac cagttgtcct tgatggtatc acatgggaga
     4741 tagaaagaag aggaacacct tctaagttag aatttacaat agttatggat gatatattag
     4801 agttttgcga aggaaattct gtaaggctgt attataaagg aataggtatc ttctatggat
     4861 atatatttca gaagaaaaga gataaagaaa atcacattaa aattgttgct tacgaccagc
     4921 taagatattt taagaataaa gatacttatg tatatagtaa taaaactgca agtgaacttg
     4981 taaaaatgtt ggctaaagat tttaatttaa aatacaatgt catagaagat actaagtata
     5041 aaatatctag gatagaagaa aataaaacac tctttgatat gattttaact gcacttgatg
     5101 atactctaag agagaaaaag gaaatgtatg tactctatga tgattttgga agattaacat
     5161 taaagaatgt tgcttctatg aaacttgata cggttatgaa caatgatgta attgaggact
     5221 ttgactacaa ttcttctatt gatagtgata cttacacaaa gattaaactt gtgagagata
     5281 atgaagaaac agggaaaaga gatgtatata ttgcacaaga ctctacacat atgaggagtt
     5341 ggggaatact tcaaatgttt gatacagtag acaaaaacat gagtgaagca gagataaaac
     5401 aaaagtgtga tatacttcta aaactatata ataagaaaac taagtcatta agtttaaaaa
     5461 atgcacttgg agatattaga gtgagagcag gttgttta
//
LOCUS       DAFAZV010000107         5006 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFAZV010000107 DAFAZV010000000
VERSION     DAFAZV010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 5006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5006
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.110"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            135..365
                     /locus_tag="KOU88_003930"
     CDS             135..365
                     /locus_tag="KOU88_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBK3213741.1"
                     /translation="MNEELFEADLKRHETRINKHGEEIDELKIANIESKAELKALCEN
                     LNSLTSMLKWLIGTMITTLVGFFIFAVQRGIF"
     gene            381..638
                     /locus_tag="KOU88_003931"
     CDS             381..638
                     /locus_tag="KOU88_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK3213742.1"
                     /translation="MDNLISFIPEQLLILVAALYVIGAGCKKYKQLDNKYIPVVLLAL
                     GIGFSIWMLGLNPVAVLQGVICWGISIGINQTYKQLKEENK"
     gene            638..1441
                     /locus_tag="KOU88_003932"
     CDS             638..1441
                     /locus_tag="KOU88_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3213743.1"
                     /translation="MKIAIVPGHTLSGKGTGTTGYIDEGKENRILTDLIVKWLKQGGA
                     TVYTGKVDKSNNYLAEQCQIANKQDIDLAVQIHFNANKTTLNAMGTETIYKTNNGKVY
                     AERVNKKLSTIFKNRGAKSDARGLYWLKHTKAPAILIEVCFVDSKADTDYYIRHKDIV
                     AKLIAEGILNKNINNKENGEGKIMYKHTIVYDGEVDKIPATVVGWGYNDGKILICDIK
                     DYVPGQTQNLYVIGGAACEKIGSMTKEKFTMIKGNDRFDTLYKALDFIK"
     gene            1500..2269
                     /locus_tag="KOU88_003933"
                     /pseudo
     CDS             1500..2269
                     /locus_tag="KOU88_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894430.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
     gene            complement(2698..3213)
                     /locus_tag="KOU88_003934"
     CDS             complement(2698..3213)
                     /locus_tag="KOU88_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213744.1"
                     /translation="MTWSDLKEKNINEVVDCINNKLSEFESLKKVGDELGANESTIRK
                     WLNKKGYKRVGNRFLEDNKSYDDKYHIDSINSKIDDDIKYLSNEIDNIKSVIEWFKTK
                     DDKCHIDSIKENDISIDLPDQSIKRTTIRVNNTVWEMFNKFADENKHYDKHDLLSQLL
                     LESLLKYVKSR"
     gene            complement(3296..4201)
                     /locus_tag="KOU88_003935"
     CDS             complement(3296..4201)
                     /locus_tag="KOU88_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParM/StbA family protein"
                     /protein_id="HBK3213745.1"
                     /translation="MSKLGIDIGNYAVKTSTDDIFESKVTEVKNFGSDSDSIKIGNKT
                     YYLGEGDEEINIVKYEKENFLPLLLGAICRNTDDEVIDLALGLPVKQFGGLRKDLIEK
                     LQGKEYHVEFAKGNETTKRDITIRSVQVFPEGVTGYLYYAKDIVDQIAGRDVVLVDIG
                     GKTTDIALVQGNKATDPYSVNVGTINIYDAIKKSLEMDERFLGKVEIKREKIQDYIDK
                     GFYLNGEKQDIKKNIDASVGLFKQIYNELKLNYPISTSAVVVMGGGAKLLGEAFKKNI
                     PGIIVMSDVDKHVFANAKGYKKMMK"
     gene            complement(4220..4423)
                     /locus_tag="KOU88_003936"
     CDS             complement(4220..4423)
                     /locus_tag="KOU88_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213746.1"
                     /translation="MSRIVLTFKNNDKEKAIEKFLDEKLSATAYLKELVWEKMNEKKD
                     NAVVEQKKEIEDPANNFDFGSLE"
     gene            complement(4673..>5006)
                     /locus_tag="KOU88_003937"
     CDS             complement(4673..>5006)
                     /locus_tag="KOU88_003937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003428607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213747.1"
                     /translation="NSDSPSTKSVVVPGGTANLTAMSGGQLHWRVTSTLGNILGFEGN
                     IDVYKAGKIVSSQFVSFRLAGTTKTGVVSFKGLKKGSYIAKFKGKGVCTGGIILFSSP
                     AEASFTIR"
BASE COUNT         1835 a          759 c          628 g         1784 t
ORIGIN      
        1 tggatgatgt aactaatgca gagtacagaa aagcagtaga ggattatata attagagaaa
       61 gtggagtaat agaaggaaca gaactaacag tataggaatg ttcctttttt atttcaatta
      121 attaggaggc ttacatgaat gaagaacttt tcgaagcaga tttaaaaaga catgaaacaa
      181 gaataaataa gcatggagaa gaaatagacg aattaaaaat agcaaatata gagtctaaag
      241 cagagttgaa agcattgtgt gagaatctaa actcacttac aagtatgctc aaatggctaa
      301 ttggtacaat gattacaaca ttagtaggat tctttatatt tgcagttcaa agaggaatat
      361 tttaattagg aggataaaag atggataatt taataagttt tataccagag cagttgctaa
      421 ttttagtagc tgctctttat gttataggag caggttgcaa gaagtataaa caactagata
      481 ataagtatat tccagtagta ttactagcac ttggaatagg tttctcaata tggatgttag
      541 gattaaatcc tgttgcagtc ttacaaggcg tgatttgttg gggtatatca ataggtataa
      601 atcaaactta caaacaacta aaggaggaaa ataaataatg aaaatagcaa tagtaccagg
      661 gcatacatta agtggaaaag gaacaggaac aaccgggtat atagatgaag gaaaagaaaa
      721 cagaatacta actgatttaa tagtaaaatg gttgaaacaa ggtggagcta ctgtgtatac
      781 tggaaaagta gataaatcta ataactattt agcagagcaa tgtcaaatag ccaataaaca
      841 agatatagac ttagcagtac aaatccattt caacgcaaat aaaacaacac taaacgcaat
      901 gggtacagag acaatataca aaactaacaa tggtaaggta tatgctgaaa gagttaacaa
      961 aaaactatca acaatattta aaaatagggg tgcaaaatcg gatgcaagag gtctttactg
     1021 gcttaagcat acaaaagctc cagcgatatt gattgaggtg tgcttcgtag atagtaaagc
     1081 agatacagac tattatatca gacataaaga catagttgct aagttaatag cagagggtat
     1141 attaaataaa aatataaata acaaagagaa tggtgaggga aaaatcatgt acaaacatac
     1201 aatcgtttat gatggagaag ttgacaaaat acctgcaact gtagttggct ggggctataa
     1261 tgatgggaaa atactgatat gtgatataaa agattatgta ccaggtcaga cgcaaaatct
     1321 ttatgtcatt ggtggtgcag catgtgagaa gattggttct atgactaaag aaaaatttac
     1381 tatgataaag ggtaatgata gatttgatac actttacaaa gcattagatt ttatcaaata
     1441 ataacttgtt gtaatatcca atcaatataa aatttattca acttaggagg acttgcaaca
     1501 tgcttaacat agaaaaatat aaactataca atggaaactg tttagaaata atggatctaa
     1561 tagaagataa atcaatagat ttaattctat gtgatcttcc ttatggcaca actaattgta
     1621 aatgggacac aataatacct ttcaaatcaa tctggaatca atataataga attataaaag
     1681 ataatggagc tatagtacta ttttcagcac aaccatttac tactagtttg ataaattcaa
     1741 atattaaaaa ctataaatat agttggtact ggattaaaaa taaatctaca ggattcgcat
     1801 tttctaaata ccagccactt cgaaaagtag aagatattaa tgtattctat aaaaagctcc
     1861 tttatacaat cctcaaaact tagaaaaatt agataaacct attacatgta aaaagaaaaa
     1921 taaaaataaa gatggaatat atagacatca tactttatca aaagaatatg ttcaagaata
     1981 tacaaattat cctaataata cattgtattt taataaagaa acaaattgca tccatccagc
     2041 tcaaaagcca gtagatcttt tagaatatct tataaaaact tatacaaacg aaaatgaact
     2101 tgttttggat aattgttttg gttctggcag tgtaggaata gcttgtgcaa atataaatag
     2161 aaagtttgtt ggaatagaat tagatagcga ttattttctt caaggtaaaa atagaattga
     2221 aagagcatac agaaacaatg caattgacaa aaacatagta aaatcctaat attagagaaa
     2281 gcaaaggata atagataaaa aaactatcct cctttgcttt ctttattttt ctatttcttt
     2341 taataatctt atacgttgca attacgcatc tgttaaatct aagattaaat aaataaaaag
     2401 actagaaaat tttattatct tctaattctt tttatttaac ttatcacaat aaaaataaat
     2461 cattttttaa tgacatttat atgatattta tcatatttag ttttgaaaca ttctagcgtt
     2521 gctttttttc tggaataact tacctgtact atcttaaata aaaaaatgct actatattat
     2581 aaaccaaata taaaataaat gatttagagc cagattattt agatagatat tttatacgat
     2641 taatgtccac tgtgcataaa tttaaaaatc tagatgaaga agattaaata tctcccttca
     2701 tctgctcttc acatatttta atagactttc aagcaataat tgacttagca aatcatgttt
     2761 atcataatgt ttattctcat ctgcaaattt attaaacatt tcccacactg tattatttac
     2821 cctaattgta gttcttttta tagactgatc tggaagatct atagatatat cattttcttt
     2881 aatgctatct atatgacatt tatcatcttt agttttaaac cattctatca cactttttat
     2941 attatcaatt tcattagata aatatttgat atcatcatca atcttactgt taatgctatc
     3001 tatatgatat ttatcatcat aacttttatt atcttctaaa aacctgtttc caactctttt
     3061 atatcctttc ttattaagcc acttccttat agtactttca tttgccccta attcatctcc
     3121 aactttttta agactttcaa attcacttaa tttattatta atacaatcaa caacttcatt
     3181 aatatttttt tctttcaaat cactccaagt catataaaac ctcctcaaaa aaataataga
     3241 ttacaaatat catatatttg taatctatta tacatactat aaactaaatc cttttttatt
     3301 tcatcatttt tttgtatcct tttgcatttg caaaaacatg tttatctaca tcactcatga
     3361 ctattatgcc aggtatattc tttttaaatg cttcacctaa caatttagca cctccaccca
     3421 taacgacaac agcagaagtt gatattgggt aatttaattt caattcatta tatatttgtt
     3481 taaataatcc aacagacgca tctatatttt tctttatatc ttgtttttca ccatttaggt
     3541 aaaacccttt gtctatgtag tcttgtattt tttctctttt tatctcaact ttacccagaa
     3601 atctttcatc catttcaaga gattttttta ttgcatcata tatatttatc gttccaacat
     3661 ttacagaata tggatcagtc gctttattcc cttgtacaag cgcaatatct gttgtctttc
     3721 caccaatatc aactaaaaca acatctcttc ctgcaatttg gtcaactatg tcttttgcat
     3781 aatataagta tcctgtaact ccctctggaa acacttgaac agatcttatt gttatatctc
     3841 ttttagtagt ttcatttcct tttgcaaatt caacatgata ttcttttcct tgtaattttt
     3901 caatcaaatc ttttcttaat cctccaaatt gcttcactgg tagacctaat gctagatcaa
     3961 taacttcatc atctgtattt ctgcatatag ccccaagtaa aagtggtaag aagttttctt
     4021 tctcatattt aactatattt atttcctcgt caccttcgcc taaataatat gttttattac
     4081 ctattttaat gctatctgaa tctgaaccaa agttttttac ctctgtaact ttactttcaa
     4141 aaatatcatc tgtacttgtt ttaactgcat aatttccaat atctatacct aatttactca
     4201 tttatgttat ttcctccttt tattctaaac ttccaaaatc aaaattgtta gctggatctt
     4261 ctatttcttt tttctgttca actacagcat tatccttttt ttcattcatt ttttcccaaa
     4321 cgagttcttt taaataagct gtagctgata atttctcatc taaaaacttt tcaattgctt
     4381 tttctttatc attgttttta aatgttagaa ctatcctact cattcaacca cttccttttt
     4441 tgtaaaatat tataaaattt attaatattt acatatattt taccaaattt cacatagtaa
     4501 ttcaatagat tcataagata ttttttataa tattttataa ttttttacgt aattttataa
     4561 ttttttataa aatttatcat tttgtatata attaagaaca cactttttat aattttgcat
     4621 aaaaaaaaga gtgtttcata tatttctaaa cactcttttc tactttttat aattatctaa
     4681 ttgtaaaaga agcttcagct ggactagaga ataatataat acctcctgta caaacacctt
     4741 ttcctttaaa tttagcaata tatgaaccct tttttagccc tttgaaactt actacaccag
     4801 ttttagtagt tccagctaat ctaaaactta caaattgaga tgatacaatt ttgccagcct
     4861 tatatacatc tatatttcct tcaaatccta aaatatttcc aagcgtagat gttactctcc
     4921 aatgtaattg tcctccactc attgctgtta aattagcagt accacctgga acaacaacag
     4981 atttagtcga aggcgaatct gagttt
//
LOCUS       DAFAZV010000108         4919 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFAZV010000108 DAFAZV010000000
VERSION     DAFAZV010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4919
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.111"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(407..757)
                     /locus_tag="KOU88_003938"
     CDS             complement(407..757)
                     /locus_tag="KOU88_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213748.1"
                     /translation="MTRSDIMFSNRLRELRKQKGLTQMELAKLLNCSLSKIAMLETDK
                     RDPVKEDLLRFSEIFDVSIDYLLGKNNLDSSPQLNKEMEQALHKLYSLDEENRKAIEK
                     IIDNAYYKIINEEK"
     gene            901..1089
                     /locus_tag="KOU88_003939"
     CDS             901..1089
                     /locus_tag="KOU88_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009587961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213749.1"
                     /translation="MKELSNFRKNLGLTQKQLAERIGISKSYYSKIEGNFKKPGRGFL
                     EKFKNTFPNEDMNIFFKQ"
     gene            1123..1911
                     /locus_tag="KOU88_003940"
     CDS             1123..1911
                     /locus_tag="KOU88_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBK3213750.1"
                     /translation="MNNLTIIKQNNKYLVESREVAELIEKDHNQLLRSIRGYISVLEQ
                     SAKLHTDDFFIESTYKNENNQKYPCYLLTKKGCDMVANKMTGEKGIIFTAIYVTKFEE
                     MERELKEQQPKLPTTYKEALQQLLIEVEEKEQLQLENQEKDKVIQLQQPKVLFADSVA
                     SSDNSILVGELAKLLRQNGIDTGQNRLFDWLRNNGYLIKRKGEDYNTPTQKSVDLGVI
                     ETKEGTRVHPDGHTSITKTPKITGKGQIYFINKFKKNNQISMLS"
     gene            2027..2275
                     /locus_tag="KOU88_003941"
     CDS             2027..2275
                     /locus_tag="KOU88_003941"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213751.1"
                     /translation="MKYNKSKVANILILTFVTCSIATTTIISLINIQNYKVIMKNLNI
                     IERNDEIIKRNDEIIKSNQNNIGKYQKIILDLQNKIQH"
     gene            complement(2272..3105)
                     /locus_tag="KOU88_003942"
     CDS             complement(2272..3105)
                     /locus_tag="KOU88_003942"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213752.1"
                     /translation="MSDKYKKIIDPFYKIREQEERRKRLFINPAEIIIKSSFKNNIVH
                     NMNLSQITQINIPKPELISIGNQCKFIDHMDSFEQVSQIIRSNEFNINQILKPAISTI
                     YETNQLFLDSITSSEIFSGNLSNSINYSIQNNIYGFVQLTENIMNKFQSYDIESVYLD
                     QDVILDSFNGIIDNATESGDIDTEISNILKRLLSKLQSAERKEKIKQFAITFFIPLAF
                     NAYFSITSGNILDKIYEEERNKTELLQDILDETKANRKTNEAILEHLKKIDENFKLEN
                     N"
     gene            3175..3372
                     /locus_tag="KOU88_003943"
     CDS             3175..3372
                     /locus_tag="KOU88_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213753.1"
                     /translation="MGIDGNLKKILKERDINVLNLSKELKIEPSNLYRITRGENKNPT
                     INTLIKIADYLDVTLDELVGR"
     gene            3402..3599
                     /locus_tag="KOU88_003944"
                     /pseudo
     CDS             3402..3599
                     /locus_tag="KOU88_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056356.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(3589..3738)
                     /locus_tag="KOU88_003945"
     CDS             complement(3589..3738)
                     /locus_tag="KOU88_003945"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213754.1"
                     /translation="MIPIAKNTKQTSKTVASKASKILKDGRYSAASKSVAGSALSQTK
                     KGPKK"
     gene            3800..3997
                     /locus_tag="KOU88_003946"
     CDS             3800..3997
                     /locus_tag="KOU88_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213755.1"
                     /translation="MAINDNINKILKDRNLKAWKLAKEIGVDSGNLYAILRGENKNPT
                     IDTLIKIADYLDITLDELVGR"
     gene            4014..4343
                     /locus_tag="KOU88_003947"
     CDS             4014..4343
                     /locus_tag="KOU88_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213756.1"
                     /translation="MSVALQFIDTKDLVQELMRRDDTTDIIKMFLDREGIKRMELMTI
                     EEFAEYLKVSDVTARNMAREAMITKDFIALKIGRKYMIDRISFEEFIMKNAMKDRDVI
                     KKRKGVI"
     gene            4445..4633
                     /locus_tag="KOU88_003948"
     CDS             4445..4633
                     /locus_tag="KOU88_003948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213757.1"
                     /translation="MRIIYKNKIYKVEQDKVLFRITYYDEQKNNRKFNNNKKVKRSVL
                     TRDIELVNLYLPAHLKIK"
     gene            4649..4861
                     /locus_tag="KOU88_003949"
     CDS             4649..4861
                     /locus_tag="KOU88_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213758.1"
                     /translation="MVFNLEKFKVGNAIRISCERFGFEIDCIVVVATEKELNLAYFDE
                     GRGCMEYQALITEDIQDGDYEIKILS"
BASE COUNT         2034 a          534 c          773 g         1578 t
ORIGIN      
        1 acgattaata atacatagga atggaaaaaa taaccaatac tctacaaatt tcgatttttt
       61 tattacaatt gcgagttttt tattgcatat atttaacaaa agtattatta taaagataag
      121 ataattatct aagacaattc tgaaaaatct aaaaatattt ctagaaatga aagggtataa
      181 ttacataagt ttattaaaaa tttgttggga atttttaact aaaaataaga acgtaggttc
      241 ttgtaatagg gggatggtac agttgaagaa agaggagtat ttaaaagaga ataaatctaa
      301 attagaaaag atatttaaat cagaaccaca aaaatatgag tatataataa aattaatcaa
      361 ttatgaagct gacaacaaaa aaaataaaag agtgtaaaaa gctcttttat ttttcttcat
      421 ttattatttt ataataagca ttatcgataa ttttctctat agctttccta ttttcttcat
      481 ccagagaata taatttgtgc aaagcctgtt ccatttcttt gtttagttga ggacttgagt
      541 ctagattatt ctttcctaaa agataatcaa tagatacatc aaaaatttct gaaaatctta
      601 ataagtcttc ttttacaggg tctcttttat ctgtttctag cattgcaatt ttactcaaag
      661 aacaatttaa taattttgcc aattccattt gtgttaaacc tttttgcttt cgcaattctc
      721 ttaatctatt agaaaacata atatcactcc ttgtcatgtt tatactacga ttgtatcact
      781 gttagtgata caaataaatc tttttttaaa aaacttcacg aaaagagata aaaagtcttg
      841 actgtgttca cttaaagtga tattattgat ttatcacaaa tagtgaaggc gaggtgtaac
      901 atgaaagagt tatcaaattt cagaaaaaat ttaggtttaa cccaaaaaca attagctgaa
      961 agaataggta tatctaagtc ttattattca aagatagaag gaaatttcaa aaaaccagga
     1021 agaggttttt tggagaaatt taaaaataca ttcccaaatg aagacatgaa catttttttt
     1081 aaacaataat atcacttaaa gtgatatgag gagggttata aaatgaacaa cttaacgatt
     1141 atcaagcaaa acaataaata cttagttgag agtagagagg tagcagaatt aatagaaaaa
     1201 gaccacaacc aattattaag aagtataaga ggatatataa gtgtattaga gcagagtgca
     1261 aaattgcaca ctgatgattt ttttattgaa agcacttata agaatgaaaa taatcagaaa
     1321 tatccttgct atctattgac taaaaaaggt tgtgatatgg tagctaataa aatgactgga
     1381 gaaaaaggaa ttatatttac agcgatttat gtaactaagt ttgaagaaat ggagcgagag
     1441 ttaaaagaac agcaacctaa actaccaact acgtacaaag aagcattgca acagttatta
     1501 atagaagttg aagaaaaaga gcaattacaa ttagaaaatc aagaaaaaga taaggtaatc
     1561 cagttacaac aaccaaaagt actgtttgct gattcggtag catcttctga caattcaatc
     1621 ctagttggag aattagcaaa attgcttaga caaaatggaa ttgatacagg acaaaataga
     1681 ttatttgact ggttaagaaa taatggttac ttaataaaac gtaaaggcga ggattacaat
     1741 acaccaactc aaaaaagtgt agatttagga gttatagaaa caaaagaagg tacaagagta
     1801 catccagatg gtcatacaag tattactaaa acacctaaga ttactggtaa gggacaaata
     1861 tactttatta ataagtttaa aaagaacaat caaatatcaa tgttaagtta aaacatgaca
     1921 gcaccttgaa aactaaatac agaatatgat taaaaataaa attatatgga actgaattta
     1981 tatatcaata actcagctcc actaactgta aaataggagg tttctaatga aatataataa
     2041 aagtaaagta gcaaatattt taatattaac atttgttact tgctcaatag caacaacaac
     2101 tattattagt ctaataaata ttcaaaacta caaagtaata atgaaaaatc taaatataat
     2161 tgaaagaaac gatgaaatca ttaaacgaaa tgatgaaatt attaaatcta atcaaaataa
     2221 tattggaaaa tatcaaaaaa taattttaga tttgcaaaac aaaatacaac actagttatt
     2281 ttctaattta aaattttcat ctattttctt tagatgttca aggatagctt catttgtttt
     2341 tctatttgct ttagtttcgt ctaatatatc ttgtagaagt tcagttttgt ttctctcttc
     2401 ttcatagatt ttatctaaga tgttgcctga tgtaatagaa aaatatgcat taaatgccaa
     2461 aggaataaaa aaagttatag caaattgttt aattttttct ttgcgttcag ctgattgtaa
     2521 tttagataat agtcttttta atatgttaga tatttcagta tcaatatctc ctgactcagt
     2581 ggcattatca ataataccat taaaagaatc taagataaca tcttggtcta aatatacaga
     2641 ttcaatatca tatgattgaa atttattcat aatattttca gttagctgta caaatccgta
     2701 aatattattt tgaatagaat aattaataga attacttagg ttaccagaga aaatttcaga
     2761 actagtaata gaatctaaaa ataactggtt cgtttcatat atcgtagata tagcaggttt
     2821 aagtatttga tttatattaa attcattaga acgaattatt tgtgatactt gttcaaatga
     2881 atccatatgg tcaataaact tgcattgatt tcctatagat ataagttctg gcttagggat
     2941 gtttatctga gttatttgag ataaattcat attgtgtact atattatttt taaaacttga
     3001 tttaataata atttctgcag gatttataaa tagtcttttt cttctttctt cctgttcacg
     3061 gattttataa aaagggtcaa taatcttttt atatttgtct gacaaattat gcaccacctt
     3121 taaatatatt tggtatttaa accatatata aattatatca caaggagaca ttaaatggga
     3181 attgatggaa atttaaaaaa gattttaaaa gaaagagata taaatgttct gaatttgtca
     3241 aaagaactaa aaatagaacc aagtaattta tatagaatta caaggggtga aaataaaaat
     3301 ccaaccataa acactctaat aaaaatagct gattatttag atgttacatt agacgaatta
     3361 gttggaagat agaaattaaa tacagagtat tttgaaaagg agtatgtaat caaatgaaaa
     3421 ttaaaaaatt agcactagca acaggagaag tatttgaaaa tatagagctc aaagagtttg
     3481 aaaataaagg agaatgctta ccatcaaata tggtaaaggt tattgatggt aagcaggaac
     3541 ttctaataaa taaagagttc atattatcat tagaagtcaa aagaaagact actttttagg
     3601 tcctttctta gtttgtgaca gagcactacc agcaaccgat ttggaagcag cactatatct
     3661 tccgtcttta agaatcttac tagccttaga agcaacagtt ttacttgttt gtttagtatt
     3721 tttagctata ggtatcacca cctttaaatg tatttatagg atatatccta caaatatagt
     3781 atatcaaagg aggaaaataa tggcaattaa tgacaacata aataaaattt taaaagatag
     3841 aaatttaaaa gcgtggaaat tagcaaaaga aataggagta gattcaggaa atttatatgc
     3901 aattttaaga ggagaaaata aaaatccaac tatagatact ctaataaaaa tagctgatta
     3961 tctagatatt acattagatg aattagtcgg aagatagaaa gggtgagata aaaatgagtg
     4021 tagcattaca attcatagat acaaaagact tagtacaaga gctaatgcga agagacgata
     4081 caacagacat catcaagatg tttttagata gagaaggaat caagagaatg gagttaatga
     4141 ctatagaaga atttgctgag tacttgaaag tatctgatgt aacagctaga aacatggcaa
     4201 gagaagccat gataacaaaa gattttattg ctttaaaaat aggaagaaag tacatgattg
     4261 atagaatatc atttgaagaa tttattatga aaaatgcaat gaaagataga gatgtaataa
     4321 aaaaaagaaa gggggtgatt tagttgaatg taagagtact gatagcttat gtacaattct
     4381 gtaagcaata taataagaaa gcaagttttg aaggtcttaa aaaatacaac aaaggggtaa
     4441 ttgcatgaga ataatttata aaaacaaaat ctacaaagta gaacaagaca aagtgttatt
     4501 tagaattaca tactatgatg agcagaaaaa taacaggaag tttaataata ataagaaagt
     4561 aaaaagaagt gttttaacaa gagatataga gttagttaac ttgtatttac cagcacattt
     4621 aaaaataaag taggaggttt aattgcatat ggtatttaat ttagagaagt tcaaagtggg
     4681 aaatgcgata agaataagtt gtgaaagatt tggttttgaa attgattgta ttgtagtagt
     4741 agcaacagaa aaagaattaa atttagcata ctttgatgaa ggtagaggct gtatggagta
     4801 tcaagcctta ataacagaag atattcaaga tggtgattat gagattaaaa ttttatctta
     4861 ggaggaaata aaatggtagg tttatttgca atatgtttag caggattatt tcaataaaa
//
LOCUS       DAFAZV010000109         4901 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFAZV010000109 DAFAZV010000000
VERSION     DAFAZV010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4901
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.112"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..980
                     /locus_tag="KOU88_003950"
     CDS             <1..980
                     /locus_tag="KOU88_003950"
                     /inference="COORDINATES: protein
                     motif:HMM:NF024786.1,HMM:TIGR04085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3213759.1"
                     /translation="NLFCKHCCVESSSNKKDLLSTYDLKNIVDIISVLNTPHIIITGG
                     EPLIREDFFEIIKYIKQKLPDTKLILSTNGTLIDEHNVDFIITNFEKIDISIDGVDEN
                     TCSETRGKGVFNKVISSVNLLKDNGFSNIKLSMVFGQKNSHLNKQFKDLNKKLGTEFV
                     ERYFIPTGRGLENKESYLIEDTVLPITIPYILDNELKMCKDKKNKKMGCCACNAGNSQ
                     IFINYDGDVYPCPSLIKDDYKMGNIFDNEFVKVIKENKTRDLKSLIKLESIYPYNFEK
                     CKDCDVNIFCWHCPAILDSVKDNELELDRWCSMMKHNLNTAVWGDEKVN"
     gene            977..1993
                     /locus_tag="KOU88_003951"
     CDS             977..1993
                     /locus_tag="KOU88_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3213760.1"
                     /translation="MKFTIFVTEDCNLRCTYCYEGNDKKKENMSYETADKTIDFICNK
                     ELESNSDYTTIVLHGGEPFINFDLIKYIHRDLVDRLSDKKILFDITTNGTIINDEIIE
                     FIAKNVKNISISIDGKKNIHDINRIDANGVGTYEKVMENGKRLIDKGIYVRARMTYNS
                     NTVKYLYESVYDIAKQGFKNIAPISDFMDKNWDNSHIKILNEQISKIMNIKKDYPDID
                     ISILDKQFINKKKGDCFGGINSYAIDTRGDVYPCTVCVGDKDILLGNIYDGLDDKKIK
                     NLIKIYISKNEECDGCTRLDYCMSTRCKLINKKVTGKFQSAVPIYCGLERVYVETTKK
                     LCSL"
     gene            2049..2210
                     /locus_tag="KOU88_003952"
     CDS             2049..2210
                     /locus_tag="KOU88_003952"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213761.1"
                     /translation="MIHIKKIEEKIELQDVEVQADPCKWYYDKHGIISQIDCMVDCAG
                     STPKGTVAY"
     gene            2418..>4901
                     /locus_tag="KOU88_003953"
     CDS             2418..>4901
                     /locus_tag="KOU88_003953"
                     /inference="COORDINATES: protein motif:HMM:NF014717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213762.1"
                     /translation="MINIKLAVSYLKRQKGKTLSLILSIGIAVMLVFSLSVINESQGQ
                     SDINHAYKNSGDYHAFYEDINSDIVKELNGEEDIKEFNDVLKFGEIISKDNGASLNLC
                     SYNKDFLDSTRYKLVKGREPRTSNELVIEQKVLDKMELDVKLNQTIDFQIVNEHINKN
                     NENSIYSKDKQFKIVGILSKSDEYYENLNKYKVRAFTYSNNGKDIVPYELITHMGTLK
                     LNTKDLDSQKVVNLGRKYKLTSNQFYPNTEVSMSMYMKNISKKTTYSIKQSLLPLLCA
                     TLVIYNMFNIIILDMTKQIGLLRAVGASKRNIRQVFFIQSIVVLSVGIVIGLLGGIVF
                     SYLGLMIVYDKSAELTINTNSIIESIIMSIIAVILASVVPIYKAGNLSIIDAIKKTDK
                     LNYIPRLLLLKSHKKVVGIINEIAFKNIFRNKVTSIIIIITISLCGVLFIGRLTSTKF
                     IYGKESDSANITSKSYGNFDIYLGYSPINANYTFSKYDNSLLNEIKAIEDVTDVEPNI
                     YLKGYLRNADLEEDYLDELKRTEINNNNESTVLIRGYNKELLNNIDKYIDKGENVYSY
                     TDRDYKNVLLVNNFYSRIKLSNNTQIIKSPKIGDLIDIKIPVYKDGEYKYINTKVRIA
                     GIMKNSYISEQDGESQSGGIQIIFNEKDLKELTGISDYNKVFVKIKKETDKKVIKEIN
                     NIIEKSGFSDIEGRYVRNHFGDHYNKSSYKLAMICVFGVLLISSINIIFIVRSNIIVR
                     LSEICTFRAIGMSKKNVKRMLIKENMIYGVLSMIVAGIISSFNYYKIVSETNKLNQQV
                     YGINNSIKFEIPIYEILIFGSISVFVCVIA"
BASE COUNT         2078 a          420 c          786 g         1617 t
ORIGIN      
        1 gcaatttatt ttgtaaacat tgttgtgttg aatcttcttc taataagaaa gatttactta
       61 gtacatatga tttaaaaaat atcgtagata taatatcagt tttaaatact cctcatataa
      121 ttataactgg tggagaacca ttgataagag aagatttttt tgaaataatt aaatatataa
      181 aacaaaaatt acctgatacc aaattaatat tatccacaaa tggaacttta atagatgaac
      241 ataatgttga ttttattata actaattttg aaaaaataga tattagtatt gatggagtag
      301 atgaaaatac ttgtagtgaa acacgaggaa aaggtgtatt taataaagta ataagctctg
      361 ttaatctgct aaaagacaat ggattcagta atataaagct gtctatggta tttggacaaa
      421 aaaattctca tttaaataaa caatttaaag atttaaataa aaagcttgga acagaatttg
      481 ttgaaagata ttttattcca acaggaagag gcctagaaaa taaagaaagc tatttaattg
      541 aagatacagt tcttccaatt acaattccgt atattttaga taatgaatta aaaatgtgta
      601 aagataaaaa aaataaaaaa atgggatgtt gtgcatgtaa tgcaggaaac tctcaaatat
      661 ttataaatta tgatggagat gtatatcctt gtccttcact gataaaggat gactataaaa
      721 tgggaaatat atttgacaat gaatttgtaa aagttataaa agaaaataaa acaagagatc
      781 taaagtcttt gattaaatta gaaagtattt atccatataa ctttgaaaaa tgtaaagatt
      841 gtgatgtaaa tattttttgt tggcattgcc cagcgatatt agattcagtt aaggataatg
      901 aattggaatt ggatagatgg tgtagtatga tgaaacacaa tttaaataca gctgtatggg
      961 gagatgaaaa agttaattga aatttactat atttgtaact gaagactgca atttgagatg
     1021 tacatattgt tatgaaggta atgataaaaa aaaagaaaat atgagttatg aaactgctga
     1081 taaaacaata gattttattt gtaataaaga attagaaagt aatagtgatt atacaacaat
     1141 tgttttacat ggaggagaac catttataaa ttttgatttg attaaatata tacataggga
     1201 tttagtagat agattgagtg acaaaaagat attatttgat ataactacaa atggaactat
     1261 tataaatgat gaaataatag agtttatagc aaagaatgta aaaaacatat cgataagtat
     1321 tgatggaaaa aagaatatac atgatataaa tagaatagat gctaacggag taggtactta
     1381 tgaaaaagta atggaaaatg gaaaaagact tatagataaa ggtatatatg ttagggcaag
     1441 aatgacatat aactcaaata ctgttaagta tctttatgag agtgtatatg atatagcaaa
     1501 acaagggttt aaaaatatcg caccaatttc agattttatg gataaaaatt gggataattc
     1561 tcatattaaa atattaaatg aacaaattag taaaattatg aatattaaaa aggattatcc
     1621 tgatatagat atatctattt tagataaaca atttataaat aagaaaaaag gagattgttt
     1681 tggagggata aatagttatg caatagatac tagaggagat gtatatccat gtacagtatg
     1741 tgtaggagat aaagatattt tactaggaaa tatatatgat ggattagatg ataaaaaaat
     1801 taagaacctt ataaaaattt atatatctaa gaatgaagag tgtgatggat gtactagact
     1861 tgattattgt atgtcaacca gatgtaaact tatcaataaa aaggtaacag gtaaattcca
     1921 aagtgcagta ccaatttatt gtggattaga aagagtttat gtggaaacaa caaaaaaact
     1981 atgtagttta taatctagtt taactagtta taataaatat aaaacaaaag taaaggggga
     2041 tatgtattat gatacatata aaaaaaatcg aagaaaaaat agaacttcaa gatgttgagg
     2101 tgcaagcaga tccatgtaaa tggtattatg ataagcatgg aataatttca caaatagact
     2161 gtatggtgga ttgtgcagga tcaactccaa aaggaacagt agcttattaa aaaatactaa
     2221 tcagtctatt aaatatgttg aaagtactag atgtagtttt ttacaaatga aatgtgattt
     2281 tctcaactct agtattttta ataattaaat ttaactagca caacgagtta gttagtattt
     2341 aatgaatagt gctctataac ctactatttt aggttataga gtttttcttg taaatatgaa
     2401 taaggaggat tctgattatg ataaatatta aacttgcggt gtcatattta aagagacaaa
     2461 aaggaaaaac tttatcatta atacttagta tagggattgc tgttatgcta gttttttcat
     2521 taagtgttat taatgaatct caaggacaat cagatataaa tcatgcatac aaaaactcgg
     2581 gagattatca tgctttttat gaagatataa atagtgatat agtaaaagaa cttaatggtg
     2641 aagaagatat aaaagaattc aatgatgtac ttaaatttgg agaaattata agtaaagata
     2701 atggagcatc tctaaattta tgctcttaca ataaagattt tttagattct actagatata
     2761 agttagttaa aggtagagag cctagaactt ctaatgaatt agtaatagaa caaaaagttt
     2821 tagacaaaat ggaattagat gtcaaattaa atcaaactat tgattttcag attgttaatg
     2881 agcatataaa taaaaataat gaaaattcta tttatagtaa agataagcaa tttaaaatag
     2941 ttggtatttt aagtaaatct gatgaatact atgaaaattt aaataaatat aaggtaagag
     3001 cttttacata ttcaaacaat ggcaaagata ttgttccata tgaattaata actcatatgg
     3061 gtacattaaa attgaataca aaagatttag attctcaaaa agtagtgaat ctagggagaa
     3121 aatataagtt aacaagtaat caattttatc caaatacaga agtaagtatg tctatgtata
     3181 tgaaaaatat ttcaaaaaaa acaacttatt caataaagca aagcttactc cctttattat
     3241 gtgcaacatt agtaatatac aatatgttta acataataat actagatatg accaagcaaa
     3301 ttggtttact tagagctgtt ggagctagca agagaaatat tagacaggta ttttttattc
     3361 agagtattgt agttttatct gtaggtatag taattggttt acttggaggt atagtttttt
     3421 cttacttagg tctcatgata gtatatgata aaagtgcaga attaactata aatacaaact
     3481 ctataattga atctatcatc atgtcaatta tagcagttat attagcctct gtagtaccaa
     3541 tatataaagc tggaaattta tctataattg atgctataaa aaagacagat aagttaaatt
     3601 atattcctag gcttttgttg ttaaaatcac ataaaaaagt tgttggaatt ataaatgaga
     3661 tagcttttaa aaatatattt aggaataagg ttacatcaat aataataata attacgatat
     3721 cactatgtgg ggttttattt ataggcagac taacttctac aaaattcata tatggaaaag
     3781 agtcagattc agctaatata acaagtaaat catatggcaa ttttgatatt tatttgggat
     3841 attcaccaat aaatgcaaat tatacatttt ctaaatatga taattcttta ttaaatgaaa
     3901 taaaagctat tgaagatgta acagatgttg aacccaatat ttatttaaaa ggatatctaa
     3961 gaaatgctga cttagaagaa gattatttag atgagctaaa aagaactgaa ataaataata
     4021 ataatgagtc tacagtttta attcgaggtt acaataaaga gctattaaat aatatagata
     4081 aatatataga taaaggcgaa aatgtttata gttatacaga cagggattat aaaaatgttt
     4141 tattggtaaa taatttttat tctagaatta aattgtcaaa taatactcag attataaaat
     4201 cacctaaaat aggagactta atagatataa aaattcctgt atataaagat ggagagtata
     4261 aatatataaa tacaaaagta agaatcgctg gaataatgaa aaatagctat atatcagagc
     4321 aagatggaga atctcaatca ggtggaattc aaattatatt taatgaaaag gatttaaaag
     4381 aattaacagg gataagtgat tataataaag tttttgtgaa gataaaaaaa gaaacagata
     4441 aaaaagtaat aaaagaaata aataatataa tagaaaaaag tggattttca gatatagagg
     4501 gaagatatgt acgtaatcat tttggagacc attataataa atcctcatat aaattagcaa
     4561 tgatttgtgt atttggagtt ttattaatat catctataaa cattattttt atagttagat
     4621 caaatataat tgtgaggttg agtgagatat gtacatttag agcaataggg atgtccaaaa
     4681 aaaatgtaaa aagaatgtta ataaaagaaa atatgatata tggggtatta agtatgattg
     4741 tagctggaat tatatctagt ttcaattatt ataaaatagt ttctgaaact aacaaactta
     4801 atcaacaggt atatggtata aataactcta ttaaatttga aattccaata tatgaaattc
     4861 taatatttgg atctatatct gtttttgttt gtgtcattgc a
//
LOCUS       DAFAZV010000110         4844 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFAZV010000110 DAFAZV010000000
VERSION     DAFAZV010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4844
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.113"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..145)
                     /locus_tag="KOU88_003954"
     CDS             complement(<1..145)
                     /locus_tag="KOU88_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003418249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213763.1"
                     /translation="MKIITIGSSLITVLLFLSTMICGFWIKNNKVTDASSIKFHMNSA
                     IFTG"
     gene            complement(142..723)
                     /locus_tag="KOU88_003955"
     CDS             complement(142..723)
                     /locus_tag="KOU88_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3213764.1"
                     /translation="MKSNDKDARERIIEVTLNLLNEVDDIEEITVRKIAERANVGVGL
                     INYHFKTKDNLLSTAIGDVMSNIIAELYDDSVYTLRPIEDLKNLLKKLCDTGLHYEKV
                     LPFVLNQCITNGDMQAELDIVPMLRKIFGNKKDEMSLRIIALQIILPIQISALSTESF
                     QLYSGINIKNKYERDKFIDILIENIIGEDVDVR"
     gene            891..1709
                     /locus_tag="KOU88_003956"
     CDS             891..1709
                     /locus_tag="KOU88_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK3213765.1"
                     /translation="MFKIGDFSKLSKISIRMLRHYDEIGLLTPSHTNKTNGYRYYSAD
                     QLSTTNRIHALKDMGFGLYSIKEILTEYNDKESLIKYLNIHHSQVKEQLEDTQKKLLK
                     IETTIKRIGGNDIMKNYDVTIKNFAPKYMMTLRRVIPTYQDEGMLWHQAFLETKDQNV
                     QIEPPKYSKAVFYDTGYKEDYVDVEVQVAVSGKYKDTEHVKFKTVPSVTAATAIVNGN
                     FNQVADACEAIGNWISDNNYDVDGPMFNIYHVSPGNDSNPDNWVTEVCFPVKKK"
     gene            2719..3540
                     /locus_tag="KOU88_003957"
     CDS             2719..3540
                     /locus_tag="KOU88_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002572585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3213766.1"
                     /translation="MKLKIVGSGGMSIIPSSFCKCKICEEARQKGGRYERLGPSLYID
                     DIKMLIDTPEDIAVACNRQKISEVKHISISHHDPDHVKGIRIVEKIGCDFITGENNPI
                     GFYALPEVIEDINRTNLDCLKYYGDVINCISINETSHVKINNFDIDLINNNPDRNITF
                     YVIKENEKKVIYACCNPKPFTHSDMYFDADVLIISLVSDDGILNDGTKLKDTPFKDEI
                     FTLDEIVEIKNYYRIKKIIITHIDEIWGKSYGYYSELEKKLDNIYFAYDGMEIIV"
     gene            complement(3850..4629)
                     /locus_tag="KOU88_003958"
     CDS             complement(3850..4629)
                     /locus_tag="KOU88_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HBK3213767.1"
                     /translation="MSYKKIAIITGANSGFGKEFLKLLINEEEITEIWAVARNKARLN
                     QLVDEFGSKVKIFSKDLSKIEEVKEIGTFLSKENVCIKYLINNAGFAKFCSYNDLSID
                     ESINMIDLNISAVVALGLICIPYMQKGSHIMNISSQASFQPLPYQNIYSSTKAFIRNY
                     TRALNVELKSKGINAIAVCPGWMSTNLFKRGIVVAEKGTKNFPGIVSPDIVAKKALKD
                     AKKNKDISVYGINTKSSHLLAKLLPQKMMMKVWLMQQHIKE"
BASE COUNT         1778 a          675 c          606 g         1785 t
ORIGIN      
        1 tccctgtaaa aatagcacta ttcatatgga acttaataga acttgcatct gttaccttat
       61 tattcttaat ccagaaccca caaatcatag ttgaaagaaa aagtaaaaca gtgataagac
      121 ttgaaccaat agttataatt ttcatcttac atcaacatcc tctccaataa tattttctat
      181 taaaatatca atgaatttat ctcgctcata tttattcttt atatttatac cactgtataa
      241 ctgaaatgat tctgtagata aagcagaaat ctgtattggt aaaataattt gcagggcaat
      301 aattcttaga ctcatttcat cttttttatt tccaaaaatt ttacgaagca tagggacaat
      361 atcaagttct gcttgcatat ctccattggt tatacattga ttcaatacaa aaggaagcac
      421 tttttcataa tgtaatccag tatcacacaa tttttttaat aaatttttta aatcttcaat
      481 aggtcttaga gtatatacac tatcgtcata tagctctgct attatatttg acatcacatc
      541 tcctatggca gtactcaaca aattatcctt tgttttaaaa tgataattta ttaaaccaac
      601 tccaacattt gcacgctcag caatttttct aactgtaatc tcctcaatat catctacttc
      661 atttaaaaga ttcaatgtaa cttcaattat acgttctcta gcatctttat cattactttt
      721 cataatagac ctccaaaaca attaacattt tcagttctga acatgttcag tataatattt
      781 ttttcatcat atgtcaatat aatttaatta taattttagt tgactctaac attatgatat
      841 ggtttatatt aatattaagc taaaagtacc tttataaagg agacaaaaac atgtttaaga
      901 taggcgattt ttcaaagcta agtaaaatta gtattcgtat gttacgtcat tatgatgaaa
      961 taggactttt aactccttct catacgaata aaactaatgg atatagatac tatagtgcag
     1021 accaactttc tactacaaac agaatccatg cactaaaaga tatgggcttt ggcttgtatt
     1081 ctataaaaga aattttgaca gaatataacg ataaagaaag tctcataaaa tatctaaata
     1141 tccaccattc tcaagtaaaa gaacaattag aagatacaca gaaaaaacta ttaaaaatag
     1201 aaaccactat taaaagaatt ggaggaaatg atattatgaa aaattatgat gtaactataa
     1261 agaattttgc accaaaatat atgatgacac ttagaagggt tataccaact tatcaagacg
     1321 aaggaatgtt atggcatcaa gcatttttag agacaaaaga ccagaatgtt caaattgaac
     1381 ccccaaagta ttctaaagca gttttttatg atactggata taaagaagat tatgtagatg
     1441 ttgaagtaca agttgctgta tctggaaagt ataaagatac tgaacatgtt aaatttaaga
     1501 ctgttccaag tgtgactgct gcaactgcaa ttgttaatgg aaatttcaat caagttgcag
     1561 acgcttgtga ggctattggt aattggatat cagataataa ctatgatgtg gatggtccta
     1621 tgtttaatat ttatcatgta agtcctggca acgatagtaa tcctgataat tgggtaacag
     1681 aggtatgctt cccagttaaa aagaagtaat ttttatatta attggataat attttaattt
     1741 gttagacaaa ttacttttag tgttatgtat aaatacctac aatttaatta ggatattatc
     1801 ttaatttgtt aaacaaatta cttttagtgt tatgtataaa tatctacaat ttaattagga
     1861 tattatctta atttgtcaga taaatcactt gtgatgttat gtttgaatga ctagaattta
     1921 atcaggatat tatcttaatt tgtcagataa atcacttgtg atgttatgtt taaatgacta
     1981 gaatttgatt gggatattat cttaatttgt cagataaatc aattgtgatg ttgtgtttaa
     2041 atgactagaa tttgattagg atattatctt aatttgtcag ataaattatt tataatgtta
     2101 tgtttaaata cctacaattt aattaggata ttatctcaat ttgtcagata aatcaattat
     2161 gattttatgt ttaaatgact agaatttgat taggatatta tcttaatttg tcagataaat
     2221 caattataag attatatact atccttatac tctagttaaa tatattttaa tcactaatat
     2281 aaattagttt ttttaacaaa acaataaaag agtaaagtac aaataattcc tttgtactct
     2341 actcttttta actttctttg tacaataata caatgataaa tataaaaaat tatatattcc
     2401 attctataga aatatgctca ccaataacat gtatgttgtt aatcaatata ttatatcaaa
     2461 ttatatcaaa attacataaa ccttatagga caatcatatc ttattacaag aaaaatgtct
     2521 tatccatatt gaataagtca ttcagttcat atacaaagtc aatttcattg agaaacattt
     2581 aatatatgtt tataaaaatt tcatactatt ctttcatatt tgcatgtgat ataatttatt
     2641 aactcataat tttgttaatc agttgtgctt gtatattatt tatataatct aatattttaa
     2701 gaaggtggtg taataacttt gaaattaaaa attgttggta gtggcggtat gtcaattatt
     2761 ccaagttcat tttgcaaatg caaaatatgt gaagaagcca gacaaaaagg cggaagatat
     2821 gaacgattag ggccaagttt atatattgat gatataaaaa tgctgataga cacacctgaa
     2881 gacattgcag tagcttgtaa cagacaaaaa atatcggaag taaaacatat ttcaatttct
     2941 caccatgacc cagaccatgt taagggtatt agaattgtcg aaaaaatagg atgtgacttt
     3001 atcacaggag aaaataatcc aattggcttt tatgcgcttc ctgaagtaat tgaagatata
     3061 aaccgaacga atctcgattg tcttaaatat tatggtgatg ttataaattg catttctatt
     3121 aatgaaactt cgcatgtaaa gataaataat tttgatattg atttgattaa caataaccca
     3181 gacaggaata taaccttcta tgttatcaaa gagaatgaaa aaaaagtcat atatgcctgc
     3241 tgtaatccca agccatttac tcatagtgat atgtactttg atgctgatgt tttaataata
     3301 agtctagttt ctgatgatgg tatattaaat gatggtacaa aacttaaaga cacaccattt
     3361 aaagatgaaa tatttacttt agatgagatt gttgaaatta aaaactatta tagaattaaa
     3421 aagattatca ttacacatat tgacgaaata tggggaaaat catatggtta ttacagtgaa
     3481 ttagaaaaga aacttgataa catttatttt gcatatgatg gtatggaaat tatagtctaa
     3541 atcattaagt aataagcata atgcaaaata agaaaacttc aatttaacag tatagttaaa
     3601 ctatgtaata tcaacatatc tcagttttta caaaatatca tagtatttat ctttataaaa
     3661 tttcaagtcc tacatatttt aatacttcaa tatctaaata aagtaaaatc aaaaatatat
     3721 tttatataca ttatagacgg cttatcggca ctagataagc cgttttgtca caattattat
     3781 ttgctcaaca aaacttctca taatatataa cagattgaat ctccaactga tacttaatta
     3841 ccgaaactct tattccttaa tatgttgttg cattaaccaa accttcatca tcattttttg
     3901 tggcaatagt tttgctaata aatgactgga ttttgtattt ataccataca cagaaatatc
     3961 cttatttttc tttgcatcct tcaatgcttt tttggcaaca atgtctggag acactatgcc
     4021 tgggaaattt tttgtccctt tttcagctac aactatacct ctcttaaata gatttgtact
     4081 catccaacct ggacatacag caattgcatt tatcccttta ctcttaagtt caacatttaa
     4141 tgctcttgta taatttctta taaacgcttt agttgaacta taaatatttt gatatggcaa
     4201 tggctggaat gatgcttgtg aagaaatatt catgatatgg cttccctttt gcatatatgg
     4261 aatacatata agtcccaatg ctacaacagc actaatattt aaatcaatca tattaataga
     4321 ttcatctata cttaaatcat tgtatgaaca gaattttgca aaaccagcat tgtttataag
     4381 gtattttata catacatttt ctttacttaa aaatgtacca atttctttta cttcttctat
     4441 ttttgataaa tcttttgaaa aaatttttac cttacttcca aattcatcta ctaattgatt
     4501 taatctcgcc ttgtttcttg caactgccca tatttctgtt atttcttctt catttattaa
     4561 taactttaga aactctttac caaaaccact attagcaccc gttataattg caatcttctt
     4621 ataactcata attattctcc tttaccataa gtttatacgc tcaaactgta aacttatttt
     4681 ttacaaataa aacaccctct attcagatgt tatattcata ttatttgaga tattatattt
     4741 atatcatttt caataattgt tatatagcat aaaaaatagt gttaatatta tagaatcggt
     4801 attgattata tttaaaaagt agtgttaatt atattataga atcg
//
LOCUS       DAFAZV010000111         4839 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFAZV010000111 DAFAZV010000000
VERSION     DAFAZV010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4839
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.114"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            54..230
                     /locus_tag="KOU88_003959"
     CDS             54..230
                     /locus_tag="KOU88_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213768.1"
                     /translation="MFKNKMDKCTHVLTAYISSSYDYCNFLDTQLDDFILEYGENVVE
                     SCLHQVMVLVSKYN"
     gene            337..537
                     /locus_tag="KOU88_003960"
     CDS             337..537
                     /locus_tag="KOU88_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213769.1"
                     /translation="MCFKTYILKRALNNKQLEITRSFDLDNLICTATEILKDNEIDLI
                     ITDEVNNVVWRNEKSTPQQENA"
     gene            complement(716..1588)
                     /locus_tag="KOU88_003961"
     CDS             complement(716..1588)
                     /locus_tag="KOU88_003961"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213770.1"
                     /translation="MSNINNKNKSWIEKHKILTIFISVIAILIICIGLPSLINRVLYW
                     DIKTHNSTDGEWLSFWGSFLGGIFGGLATLGAILITREMAKKDNEELKESISMEREPK
                     VIPIKKNAYLYKTYGSPCMFNEIKTSSEVPRCSDIIELTLVNVGKEAAIQIEVFWEKP
                     LNIVKTEYLTDDDLEVCNNFFDEFDENENIKVEKEYISSLQEVEIGLNAYTEMYIREL
                     SSKLIDNFRENNEDGIYIRKNIKAGTINIKCKNIYDKSYNKSYDMEISIFEMDRSKEL
                     YTINIDFNLIEDEG"
     gene            complement(1785..2369)
                     /locus_tag="KOU88_003962"
     CDS             complement(1785..2369)
                     /locus_tag="KOU88_003962"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213771.1"
                     /translation="MKGEYNKEKEKVIKFNSNKDKSKINKYTDYYNTLNSTLMEKNKC
                     IGDNWFLATTSEEVGNMNEEEKRILETEKRILETEKRVHQNNKEVKESIDKQFNDIKG
                     IFKEYKNDLDKDRIELKNDLARERIELKSDLKEAINEHKKVTEKDVSEIKNSIKGIED
                     RIDSTNKWIIALCITTIIGIATMAITIGISIWPK"
     gene            complement(2372..2863)
                     /locus_tag="KOU88_003963"
     CDS             complement(2372..2863)
                     /locus_tag="KOU88_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213772.1"
                     /translation="MAYENGTNLVAYFPNCIKKYEKDNKIFEKTILLLNLYMQMPTWP
                     HCIHEFKAKANEILGEDPEFIGEYGIKLKDFYNEGENVNISQNFKNDLYTFSNSTYDI
                     LDNSYIQRINPIGLYSISSLARENDFILKLFRNDKKSLELELSKSEIQSIIEHLESMI
                     EEE"
     gene            complement(3113..3925)
                     /locus_tag="KOU88_003964"
     CDS             complement(3113..3925)
                     /locus_tag="KOU88_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3213773.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKVDVIICPERQFKTKNEEKSYKIPKINNGGYDLLIELHLNASDGQGKGSEVLYYSN
                     KGLEYATRICKKLGTVFKNRGAKLDKGLYILNSSKPTAVLIESFFCDNKEDYEKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKIPATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVVGGVACEKIGSMTKEKFTMIKGNDRFDTLYKALEFINK"
     gene            complement(3925..4416)
                     /locus_tag="KOU88_003965"
     CDS             complement(3925..4416)
                     /locus_tag="KOU88_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK3213774.1"
                     /translation="MHLKDLDNSRSFLIQKLGGNMNLTIVFLATNIFIKLVILAIAFD
                     TLLGCLRAIKTHQFNSSFGINGGIRKVAMIACIFFLAVVDILTKFNFLFMLPQDWVDF
                     LRLNHLGISEFFSILFILYESVSILKNMYLCGLPVPKRLKEKIGSLLDTMTDELNVKG
                     GSK"
     gene            complement(4427..4645)
                     /locus_tag="KOU88_003966"
     CDS             complement(4427..4645)
                     /locus_tag="KOU88_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213775.1"
                     /translation="MKKIIVICILVLMLIIPTMGEIFIMVENIKLEGLEQNPTSCYIS
                     NPGIMGEAKCDAAYFIIAADFVNNLKVK"
BASE COUNT         1554 a          792 c          476 g         2017 t
ORIGIN      
        1 agatagtgtt ctttttgttt ttatgaaagt tttttagggg gataataatt tatatgttta
       61 aaaataaaat ggataaatgt acacatgtac tgactgctta tattagcagt tcgtatgatt
      121 attgtaattt tttagataca cagttagatg attttatatt agagtacgga gaaaatgtag
      181 tagagtcttg tttacaccaa gtaatggtat tggtaagtaa gtataattag atagacattg
      241 atttctagag aacccttttt agttttatct acatttaaat attactatgt taaaaaatta
      301 attaaagtat ctttgtgaga aaggataata atataaatgt gttttaagac ttatatatta
      361 aaaagagcat taaataacaa acaactagag ataactcgaa gtttcgacct agataatctc
      421 atttgtactg caacagagat tttaaaagac aatgagattg atttaataat tactgatgaa
      481 gtaaataatg ttgtttggag aaatgaaaaa agcactcccc agcaagagaa tgcttagtta
      541 tagctataga agtgtactac gaatacactt ctattttttt attatatcat aaattattca
      601 tagtattaag taaaaataga gctaatacaa tcagttttaa aatagcttga atagctttct
      661 tgagttattt acctttgcat aaattattga atatttgaaa taaaaaaaga taggtttacc
      721 cctcatcttc aatcaaatta aagtctatat ttatagtata taattcttta cttctatcca
      781 tttcaaatat tgatatttcc atatcatatg atttattata ggatttatca tatatattct
      841 tacatttaat attaattgta cccgccttaa tatttttcct aatatatata ccatcttcat
      901 tattttctct aaaattatct ataagtttac tagataattc cctaatatac atttcagtat
      961 atgcgtttaa acctatctca acttcttgta aagaagaaat atattctttc tcgactttaa
     1021 tattttcgtt ttcatcaaat tcatcaaaga aattattaca tacttctaaa tcatcatctg
     1081 ttaaatattc agttttaact atattcagag gtttttccca aaatacttct atttgtattg
     1141 ctgcttcttt ccctacattc acaagtgtta attctataat atctgaacat cttggcactt
     1201 cgcttgatgt cttaatttca ttaaacatac aaggactacc ataagtttta tacaaatatg
     1261 catttttctt aataggaata accttaggct ctctttccat agatatactt tcttttaatt
     1321 cttcattatc ttttttagcc atttctctag ttatcaatat agcacctaat gttgctaacc
     1381 ctccaaatat accacctaaa aaactgcccc aaaaacttaa ccactcacca tctgttgaat
     1441 tatgtgtttt tatatcccaa tataacaccc tatttattaa cgatggtaag ccaatacata
     1501 taataagaat tgctattaca cttataaata tggttagtat cttatgcttt tcaatccaac
     1561 ttttattttt attgtttata ttgctcatta ctttccctcc gttctataat atatatttta
     1621 ccattttgta caaaatggta aaatatatta tgggataaat attatttgga tataaacttt
     1681 ccttttgtat taagatatta tcaatctctt attttatcta taatatgtta tttttaagcc
     1741 taaaaaagag ataactattt taatcctagt tacctctttt tatgttattt tggccatata
     1801 gatataccta ttgtaatagc cattgtagca attcctatta tagtagttat acataatgca
     1861 ataatccatt tattagttga atcaattcta tcttctatac cttttatact attctttatt
     1921 tcacttacat ccttttctgt caccttttta tgttcgttta tagcttcttt taaatcgctt
     1981 tttaactcaa ttctttctct agctaaatca ttttttagtt ctattctatc tttgtctaaa
     2041 tcattcttgt attctttaaa aatacccttt atgtcattaa attgcttatc tatactttct
     2101 tttacttcct tattattttg atgtactctt ttttcagtct ctaatattct tttttcagtt
     2161 tctagtattc ttttttcttc ttcattcata ttacctacct cctctgaagt agtagctaaa
     2221 aaccaattat ctccaataca tttatttttc tccatcaaag tactatttaa agtattataa
     2281 tagtctgtat atttgttgat tttactttta tccttgttgg aattaaactt tattactttt
     2341 tctttttctt tattatattc acccttcata actattcttc ctctatcata gactctaaat
     2401 gttcaattat tgattgtatt tctgatttag atagttctaa ttccaaagat tttttatcat
     2461 ttctaaatag tttcaaaata aaatcatttt ctctagccaa agaagatata gaatataagc
     2521 caattggatt gattctctga atatatgagt tatctaatat atcatatgta ctatttgaaa
     2581 aagtatacaa atcattttta aagttttggc ttatatttac attttcacct tcattataaa
     2641 agtctttcag tttaattcca tactcaccta taaattctgg gtcttctccc aaaatttcat
     2701 ttgctttagc tttaaattca tgaatacaat gtggccaagt tggcatctgc atatataaat
     2761 taagtaatag tattgtcttt tcaaatattt tgttatcctt ttcgtatttt tttatacagt
     2821 taggaaaata cgctaccaaa ttagtcccat tttcataagc catcttaact ccccctaaaa
     2881 taatattatt taatactatt ctacattata attactttca ttgcactatt attttttatt
     2941 cctcctccta ccacttattg ctatatactc aactgctctt catatacctg attttttaaa
     3001 gtttgtagat gacttatggt tatatttaat atatcatttt ttattttata aattgttgtg
     3061 atactgtcat aaaattgtag tcaaaatgta aaatatatta actctattga ttttatttat
     3121 ttataaactc cagtgcttta taaagtgtat caaatctatc attacccttt atcatagtaa
     3181 atttttcttt agtcatagaa ccaatcttct cacatgctac accgcctaca acataaagat
     3241 tttgcgtctg acctggcacg taatctttta tatcacatat cagtattttc ccatcattat
     3301 aaccccaacc aaccacagtt gcagggattt tgtcaacttc tccatcataa actattgtat
     3361 gtttgtacat ctgtttaact ccctcattat ttatattttt atttaataca ccttctacaa
     3421 ttaacttagc aataccttca tgacctagtt tcttagcttt ctcataatct tctttattat
     3481 cacaaaagaa actttcaatt aatactgctg taggtttgga gctgtttaaa atatataatc
     3541 ctttgtctaa tttagcacct ctatttttaa atactgttcc taatttcttg catattctag
     3601 ttgcatactc tagaccttta ttactataat atagcacctc tgagcctttt ccttgaccat
     3661 cacttgcatt tagatgtagt tctatgagta agtcatatcc tccgttatta atcttaggta
     3721 ttttataaga cttttcttca ttcttagttt taaactgtct ttctgggcat attattacat
     3781 ctaccttatg tccttctttt ctaaatgtat ctgctaatac tggtgcaaga gatttattat
     3841 attggtactc gttaactact ccatcagcag aagtacatgc tccacttttt aaaatgctgt
     3901 gtcctactgt aatacatatt ttcattattt actacctcct ttaacattta attcgtctgt
     3961 catagtatct aataaactac ctattttctc ttttaatcgt ttaggaactg gtaatccaca
     4021 taagtacata ttttttaata tacttacact ttcatataga ataaataaaa tagaaaaaaa
     4081 ttcagatatt ccaagatgat ttaatcgcaa aaaatcaacc caatcttgtg gtaacataaa
     4141 taaaaagtta aactttgtaa gaatgtcaac tactgctaga aaaaatatac atgctatcat
     4201 tgcaactttt cttattcctc catttattcc aaaacttgaa ttaaactgat gtgtttttat
     4261 tgctcttaag caacctaaca gtgtatcaaa tgctattgct aatattacta attttataaa
     4321 tatatttgtt gctaaaaaaa ctattgttaa attcatattt cctcctaatt tttgtattaa
     4381 aaaggaccta gaattatcta agtcctttaa atgtattaat ttattattat tttaccttta
     4441 aattgttaac gaaatccgca gctataataa agtatgctgc atcgcatttt gcttctccca
     4501 taattcctgg attagaaatg taacaacttg ttgggttttg ttctagcccc tctagcttta
     4561 tattttctac cattataaat atctccccca tagtaggtat aattaacatt agaactagaa
     4621 tgcaaattac aattattttc ttcatttttt aatctccttt taatagaatt tttttattat
     4681 agataaaaat aaaaaatata taactaaaaa aggaaattat ttttaattta tataaaaaaa
     4741 gaacctactt tgttggttct gctccttcta ctactccact ttctctaatt atataatctt
     4801 ctactgcttt tctgtactct gcattagtta catcatcca
//
LOCUS       DAFAZV010000112         4831 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFAZV010000112 DAFAZV010000000
VERSION     DAFAZV010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4831
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.115"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..561
                     /locus_tag="KOU88_003967"
     CDS             <1..561
                     /locus_tag="KOU88_003967"
                     /inference="COORDINATES: protein motif:HMM:NF021182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213776.1"
                     /translation="TGLKDYHGREVYEGDIVSCNDLVHESDFLCEVKFLDGRFVVIND
                     LLKEKISLFEESLDIEIVGNIYENTGMLEMIRKNKINVCYQCRNEDISEDARYCKICG
                     IGLRVMELVSVFNFETGEEVYSFLTGKECLIDFGDLREDNPCKLFFENAELRINGVKS
                     FYQDERGIFIKDDEYSYRIIFKDLEW"
     gene            565..903
                     /locus_tag="KOU88_003968"
     CDS             565..903
                     /locus_tag="KOU88_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213777.1"
                     /translation="MAKVWVDAGTFLEKTIDIEDMFELNLRAIRKRNEKIKNEIEKQI
                     KYEDSEIKTTNRGGPGKSIKVFNINTGEVKILKSAKEASKYIKVSCSHASYLARENKS
                     TEDGWKAEYI"
     gene            914..1075
                     /locus_tag="KOU88_003969"
     CDS             914..1075
                     /locus_tag="KOU88_003969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213778.1"
                     /translation="MVLANVEQVIKLAEKILSKKKCSVNKAIDIAIKILSRYEYEGML
                     RNESTNAVN"
     gene            1050..1211
                     /locus_tag="KOU88_003970"
     CDS             1050..1211
                     /locus_tag="KOU88_003970"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213779.1"
                     /translation="MKVQMQLTKDKEFFKVYVNSEEEELERLFFEFVSQMLAYKRNEN
                     KRKQGDIEK"
     gene            1208..1381
                     /locus_tag="KOU88_003971"
     CDS             1208..1381
                     /locus_tag="KOU88_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3797 domain-containing protein"
                     /protein_id="HBK3213780.1"
                     /translation="MKLKDIIKLGEKYCYCPRCGNDKIGNDEGKLIVEEHTYYRECSC
                     GFNILIDDRKDEI"
     gene            1500..1658
                     /locus_tag="KOU88_003972"
     CDS             1500..1658
                     /locus_tag="KOU88_003972"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213781.1"
                     /translation="MDDRLEICKKMFPIITKNTRLLCHYCDGRNICSYDEEKAHELLR
                     NEEGAKND"
     gene            1710..1985
                     /locus_tag="KOU88_003973"
     CDS             1710..1985
                     /locus_tag="KOU88_003973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213782.1"
                     /translation="MEYKEYEDLKNRVESYEDLQGSAEFAGRVIENLEDIDCPIRIGF
                     KFPSKEDYKNIELDIAAKDSNSIFIRTELAKAFKEILSKYEMDMENI"
     gene            2079..2300
                     /locus_tag="KOU88_003974"
     CDS             2079..2300
                     /locus_tag="KOU88_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213783.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSKEMLKQKAELLAKDDKILL
                     VTIDKVEEVIKDIRSQKMAEYYCDGGIEI"
     gene            2297..3301
                     /locus_tag="KOU88_003975"
     CDS             2297..3301
                     /locus_tag="KOU88_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBK3213784.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDIEAFFQKKISKVSR
                     DNDIRTAVFNDYSNNLIKKCCEQIIYDESSFLNNSKEIAAYLFDVMKLNATLESCDLA
                     ICLYSQKDEKKVAILKLDYNKSYTHSIEFKDDKFNIQMSANEVNIQETKTVKVAALVG
                     LSGMNDEYHLRVLDKDAEKEEANSKFVTEFLNATKVKDDKYKTKKFKNTAENWITNAL
                     SNDIKQAEDVRSILNYTLIEKHEIDINDFVDKTIKDDKLKDSFKEHMEEKGLDESFSI
                     DKKWVEKKLKKRNIKTDNGFEIKGNLTDFEDPMKYTVRQNQNGSIDIIIKNVNFYNEK
                     "
     gene            3312..3602
                     /locus_tag="KOU88_003976"
     CDS             3312..3602
                     /locus_tag="KOU88_003976"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213785.1"
                     /translation="MENKDNFVLNKLGPASKVMKKVEIDEKEIKSYLKELKECEEVKV
                     FIIRKDGIEIPIVFKDGNMNEWLRKEIEISFDRFKDEIAQVKKALIKVTGEN"
     gene            3622..3789
                     /locus_tag="KOU88_003977"
     CDS             3622..3789
                     /locus_tag="KOU88_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213786.1"
                     /translation="MTNKEMCKSNNLDEREVCKEFGKEICGSCINDRVDCESKDCDIA
                     YENWLEKNTER"
     gene            3873..4214
                     /locus_tag="KOU88_003978"
     CDS             3873..4214
                     /locus_tag="KOU88_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor-like protein"
                     /protein_id="HBK3213787.1"
                     /translation="MANIYCENYNCKNYFEDMCMLERIEINNFKECESYLEGKNELYE
                     LENGYTIHPKDLKMVKSKDYSVEVTHIPTGITVKCRSTNSILKNKNKCLEALEEELTK
                     INSHLELEDLR"
     gene            4340..4747
                     /locus_tag="KOU88_003979"
     CDS             4340..4747
                     /locus_tag="KOU88_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBK3213788.1"
                     /translation="MKVFLVIDGEPVGKERPRFNLATKRTYTPQKTKDYEELIKWLYQ
                     SKVRHYFTGYIKMTLRCYYSIAKSNSKKIKEQKRNNVLRPNKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDKPRVEVILEDVI"
BASE COUNT         2042 a          390 c          979 g         1420 t
ORIGIN      
        1 acaggtttga aggattacca tggaagagaa gtatatgagg gcgatattgt ttcatgtaat
       61 gatttagtac atgaatctga ctttttgtgt gaagttaagt ttttagatgg aagatttgtt
      121 gttataaatg atttgctaaa agaaaaaata tctttatttg aagaaagtct ggatattgaa
      181 attgttggaa atatatatga aaatactgga atgttagaga tgataagaaa aaataagatt
      241 aatgtttgtt atcaatgcag aaatgaagat ataagtgaag atgcaagata ttgtaagatt
      301 tgcggaatag gattaagagt tatggaatta gtaagtgttt ttaactttga aacaggagaa
      361 gaagtttact cattcttaac aggcaaagaa tgtcttatag attttggaga tttaagagaa
      421 gataatccat gtaaattatt cttcgaaaat gcagagttaa gaattaatgg agtaaaaagc
      481 ttttatcaag atgaaagagg gatattcatt aaagatgatg agtacagcta tagaataata
      541 tttaaagatt tggagtggta gaacatggct aaagtttggg tagatgcagg aacgttttta
      601 gaaaaaacta ttgatataga agatatgttt gaacttaatt taagagcaat aagaaagaga
      661 aatgaaaaaa taaaaaatga aattgagaaa caaataaaat atgaagattc agaaataaaa
      721 actacaaatc gtggtggacc aggaaagtct ataaaagttt tcaatataaa tactggagag
      781 gtcaagattc ttaagagtgc taaagaagca agtaaatata taaaagttag ttgcagtcat
      841 gccagctatt tagctagaga aaataaatca actgaggatg gttggaaagc agaatatatt
      901 taagaggtgt cagatggtac tagcaaatgt ggagcaagta attaaattag ctgaaaagat
      961 actaagtaag aaaaagtgtt ctgttaataa agctattgat atagctataa aaatattaag
     1021 taggtacgaa tatgagggga tgttgagaaa tgaaagtaca aatgcagtta actaaagaca
     1081 aggagttttt caaagtttat gtaaattcag aagaagaaga actggagaga ttgttttttg
     1141 aatttgtatc acaaatgtta gcttataaaa gaaatgaaaa caagagaaag caaggagata
     1201 ttgagaaatg aaattaaaag atattataaa acttggagaa aagtattgct attgtcctcg
     1261 ttgtggtaat gacaagattg gaaatgatga aggcaagtta atagttgaag aacacacata
     1321 ttatagagaa tgttcatgtg ggtttaatat actgattgat gataggaagg atgaaatcta
     1381 atgaacatgt tagctagtgt gatattagta ataggaagtt ttataactgg tagagtttat
     1441 gagtatagat tgaatctaaa agagtgtgaa aattgtgata acaaaagggg ggtataagaa
     1501 tggatgatag attggagatt tgcaaaaaaa tgtttcctat cattactaaa aatactagat
     1561 tgctttgtca ttattgtgat ggtagaaata tttgcagtta tgatgaagaa aaagctcatg
     1621 aattattgag aaatgaagag ggtgctaaaa atgactaatt ttgaaatgat aaaatatcta
     1681 attaaaacag tttagaggag gaatagatta tggaatataa agaatatgaa gatttaaaaa
     1741 atagagtaga aagttatgag gatttacaag gtagtgcaga gtttgcaggg agagttatag
     1801 aaaatcttga ggatatagat tgccctataa gaataggatt taaatttcct agcaaagagg
     1861 attacaaaaa tatagaactt gatatagctg ctaaagattc aaattcaatt tttataagaa
     1921 cagagttagc aaaagcattt aaagagattt tatctaaata tgaaatggat atggaaaata
     1981 tctaattaaa acagtttaga gagttgcaaa atgtctttta gtatgagtat tgttgaagtg
     2041 ttttgtgact ctcaaaaatg aaataaaggg gtgaacaaat gtcaaagtat gtgcttagat
     2101 ggcaaaaagg gttattgttg gatgaacgta agataaatta ttcttgtgga agtaaggaaa
     2161 tgttaaaaca aaaagcagaa ttattagcta aagatgacaa gatactgctt gtaacaatag
     2221 ataaagttga agaagttata aaagatatta gaagtcaaaa aatggctgaa tattattgcg
     2281 atggaggaat tgaaatatga taatacacaa atttataata catgttttag ataagaatag
     2341 cgatacacca atactaaatg actttgaggg tagagtcagt caagatattg aagctttctt
     2401 tcaaaagaag ataagcaaag tatcaagaga taatgacatc agaacagcag tatttaatga
     2461 ctatagtaac aatctaatta agaagtgttg tgaacaaatt atttatgatg aaagttcatt
     2521 tttaaataac tctaaagaga ttgcagctta tttatttgat gttatgaagc ttaatgctac
     2581 attagaatct tgtgacttag caatttgctt atactctcaa aaagatgaaa agaaagttgc
     2641 tatattaaaa cttgattaca acaagtcata tactcattca atcgagttta aagatgataa
     2701 atttaatata cagatgtcag ctaatgaagt taatatacaa gaaactaaaa cggtcaaagt
     2761 tgctgctttg gttggattaa gtggaatgaa tgatgaatac catcttaggg ttttagacaa
     2821 ggatgcagaa aaggaagaag ctaattctaa gtttgttaca gagtttttaa atgctactaa
     2881 agtgaaagat gacaagtaca agactaagaa gttcaaaaat acagctgaga attggataac
     2941 taatgctctt agtaatgata taaaacaagc agaggatgta agaagtatat taaattatac
     3001 tttgatagaa aagcatgaaa ttgatataaa tgattttgtt gataaaacaa ttaaagatga
     3061 taagttaaaa gatagtttta aagaacatat ggaagaaaag ggtcttgatg aaagttttag
     3121 catagataaa aaatgggttg aaaaaaagct taaaaagaga aatataaaaa ctgacaatgg
     3181 ttttgaaata aaaggtaact taactgattt tgaggaccca atgaaatata cagtaagaca
     3241 aaatcaaaat gggtctatag atataattat taagaatgtt aatttctata atgaaaaata
     3301 agggggctac aatggaaaat aaagataatt ttgtattaaa taagcttgga ccagcaagta
     3361 aagtaatgaa aaaagttgaa atagatgaaa aagaaattaa gagttatcta aaagaactaa
     3421 aagaatgtga agaagtaaaa gtttttatta ttagaaaaga tggaattgaa attccaatag
     3481 ttttcaaaga tggaaatatg aacgaatggt taagaaaaga aattgagata agttttgata
     3541 gatttaagga tgaaattgct caagttaaaa aagcattgat taaagttaca ggagagaatt
     3601 aagaagttag aaggtgctca tatgactaat aaagaaatgt gcaagtcaaa taatcttgat
     3661 gaaagagaag tgtgtaagga atttggaaaa gagatttgtg gtagttgtat aaatgatagg
     3721 gtagattgcg aaagcaaaga ttgtgatata gcatatgaaa attggctaga gaagaataca
     3781 gaaagataat tataaaaata aagtcaaggt aagtttgtga atgaaactag aatgttatag
     3841 acttactttg acttataaaa ggagtgcgtt aaatggctaa tatatattgt gaaaattata
     3901 attgtaaaaa ctactttgaa gatatgtgta tgcttgaaag aattgaaatt aataacttca
     3961 aagaatgcga aagctatctt gaaggtaaaa atgagctata tgaattagaa aacggatata
     4021 ctatacatcc taaagatttg aaaatggtga aaagtaaaga ttattctgtt gaagttactc
     4081 atattccaac tggtattaca gtaaaatgcc gttctacaaa tagtatttta aaaaataaaa
     4141 ataagtgttt ggaagctcta gaagaagaac taacaaaaat aaactctcac ttagagctag
     4201 aagatttacg ctaaatagga agtgagctta tgaaacgaag aagatgcagt tggtgtggta
     4261 agttatttta tcttgaagaa aaatctaagg atgtttattg ttgtaaagaa tgtaggaaga
     4321 aggctaagaa ggtgaaaaaa tgaaagtttt tcttgtaata gatggagaac cagttggtaa
     4381 agaaagacct agatttaact tggctactaa aaggacctat acaccacaga aaactaagga
     4441 ctatgaagaa ttaataaaat ggttatatca atctaaagtt agacattatt ttactggata
     4501 cataaaaatg actttaagat gttattactc tatagcaaaa agtaacagta aaaagattaa
     4561 agagcagaaa agaaataatg tgttaagacc caataaaaaa ccagatattg ataatgtggt
     4621 caagattata gctgattcac tcaatgagat agcttataaa gatgatacgc agattgttga
     4681 ggttgtagct agtaaatatt acagtgataa accaagagtt gaggttatat tagaagatgt
     4741 tatttaacca acggaaaaat ccgttcgtta gattaggtac tcagtttttc ataaaaatgt
     4801 gaaaaagctg aatagagaat atatcaaatg g
//
LOCUS       DAFAZV010000113         4756 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFAZV010000113 DAFAZV010000000
VERSION     DAFAZV010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4756
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.116"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            187..1338
                     /locus_tag="KOU88_003980"
     CDS             187..1338
                     /locus_tag="KOU88_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBK3213789.1"
                     /translation="MEIYLDNSATTKPYQEVIDKMVYALNTEYGNPSSVHRKGVEVEK
                     AIKEVRQDIAKSLGAKEKEIYFTSGGTECNNTIIRGITSLNKKRKNHIISTNIEHPSV
                     LNTLKDLEEDGFEVTYLEVGKDGKINIEDLKNAIKSTTCLVSMMHVNNEIGTIQPIGE
                     VGKYLKGLKEKIYFHVDAIQSYGKINFRPSKYNIDFMSVSAHKFHGPKGIGFMYIKEN
                     NRLKPMLTGGGQEIGIRSGTENVPGIYGLGEAVRILNKDLDAVISKVDNLKNILKNEI
                     IDNIEDIKINSPEDGVCHILNVSFRGTKGEVLLHYLEQKGIYVSTGSACSSKKKGSYV
                     LNAIGLTNEEINGTIRFSLSDMNTEEEMLEAVKVLKESICDLRSIMKRK"
     gene            1384..2559
                     /gene="thiI"
                     /locus_tag="KOU88_003981"
     CDS             1384..2559
                     /gene="thiI"
                     /locus_tag="KOU88_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003437440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBK3213790.1"
                     /translation="MVYNILIVKYGEIGVKGKNRYIFENRLIRNIRNMLKPIGRFNVY
                     KEYGRIYVDLEDYDYEEVIEEVRKVFGIVGVCPGVRAKKDYDTLKEIALKMLEEKIEA
                     GYKTFKVESRRGDKSFGLTSQEMSMDIGGYLLSKVGDRINVDVRNPEVKIKCEYREFH
                     TMVYSDTIPGYGGLPLGTNGRAMSLLSGGIDSPVATWMVAKRGMEVEAVHFHSYPFTS
                     ERSQEKVKDLAKILAKYCGRVRLHKVNILEIQKAIGENCNEEETTILSRRFMMRIAQR
                     LSEKRHCDALITGESIGQVASQTIQGLTCTNAVVDLPVFRPLIAMDKSDIVDIAKKIG
                     TFETSIVPEEDCCSVFSPRKPVTKPRLEKIEKSETALDIEKLVQDAIDKIEVEDIEF"
     gene            2695..3498
                     /locus_tag="KOU88_003982"
     CDS             2695..3498
                     /locus_tag="KOU88_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBK3213791.1"
                     /translation="MNKKGFTLIELLVVISIIGILVIVAVPALFRNIEKSKAVTCLSN
                     RENIKTQIVIAMAEESSKDKNEVIKEVLENKDGKYFETEPKCKSGGIYSATFDDGYDG
                     ITGIESIAKVYVTCTKHPDGVEMARDVHQSMKDLIASFAQDPSIIPGASKGNDDFRKY
                     LLDNKYKNGWPTIPDEFKAKYGLSKDTLYIQPYAYNPTKSDATVVVFANNKTGGNWYT
                     SLVYDYDEGRWYKGKNGISVAGRSWDVDTDSVKSVKTEIHSKEGWGPLN"
     gene            3741..4382
                     /locus_tag="KOU88_003983"
     CDS             3741..4382
                     /locus_tag="KOU88_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HBK3213792.1"
                     /translation="MNNNFQDNQTINLIQSRRSIRKFTTEQISDEQVNTLLHCAFAAP
                     SGCNKQPWHITVVQDQKLLKEISDDTLSRIHEVSNVEINKNFKLFYSAPTVLFISYDE
                     SSSWAPYDIGILTGNITTAAQALGLGSCIIGMVRGLFTPVEQGDIEGLVSVLDKEDVK
                     ESESIKMKFDTNKKYRELLDIPEGYSVPFGIAVGIPDGNLPNAREVVYKVSRV"
BASE COUNT         1918 a          454 c          918 g         1466 t
ORIGIN      
        1 ggtatagtat aagtatatta tattttacta taaaaatttg taataaagtg aaaaaactag
       61 cttttcatga aataatattt tataatttaa gattgtcttt ttaataaaga ttaacaaaaa
      121 aaatactata attagtggta taatagttag agttgaagat tttaaataaa ggtaggtgta
      181 attaagttgg aaatatactt agacaatagc gcaactacaa aaccttatca agaagttata
      241 gataaaatgg tttatgcact taatacggaa tatggaaatc cttcttctgt ccatagaaaa
      301 ggtgtagaag ttgaaaaagc tataaaagaa gtaagacaag atatagctaa atctctagga
      361 gcgaaagaaa aggagattta ttttacatca ggtggtacag agtgtaataa tactataata
      421 agaggtatta ctagtttaaa taaaaaaaga aaaaatcaca taatatctac taacatagaa
      481 catccttctg ttttaaatac attaaaagat ttagaagaag atggttttga agtaacttat
      541 ttagaggtcg gaaaagatgg gaaaataaat atagaggatt taaaaaatgc gataaagtca
      601 actacatgct tagtaagcat gatgcatgtt aacaatgaaa taggaactat acagccaata
      661 ggtgaagttg gaaagtattt gaagggttta aaagaaaaaa tttatttcca tgttgatgct
      721 attcaatcat atggaaaaat taactttaga ccatctaaat acaatataga ttttatgagt
      781 gtaagtgcac ataaatttca tggtccaaag ggaattggat ttatgtatat aaaagaaaat
      841 aatcgcctta agcctatgtt aacaggtggt ggtcaggaaa ttggaattag gtcgggaaca
      901 gaaaatgtac ctggaatata tggtcttgga gaagctgtta gaatactaaa caaagattta
      961 gatgctgtta tttcgaaagt agataactta aaaaatatat taaaaaatga aataattgat
     1021 aatatagaag atataaaaat caattctcca gaagatggag tatgtcatat attaaatgta
     1081 tcatttagag ggacaaaagg agaagtttta cttcattact tagagcaaaa aggtatttat
     1141 gtatcaactg gctctgcatg ttcttctaaa aagaaaggta gttacgtatt aaatgctata
     1201 ggtcttacaa atgaagaaat aaatggaaca ataagattta gtttatctga tatgaataca
     1261 gaagaagaaa tgttagaagc tgtgaaagtt ttgaaagaat caatttgtga cttaaggtca
     1321 ataatgaaaa gaaaataaag aatactgtat aaatagtgat aataaattag tttaagaggt
     1381 gaaatggtgt ataatatatt aatagtaaag tatggagaaa ttggagtaaa aggaaagaat
     1441 agatatatat ttgagaatag gcttataaga aatataagaa atatgttaaa accaattgga
     1501 agatttaatg tatataaaga gtatggaaga atatatgttg atttagaaga ctatgattat
     1561 gaagaagtaa ttgaagaagt tagaaaagta tttgggatag tgggtgtgtg ccctggagta
     1621 agagctaaaa aagattatga tacattaaaa gaaatagctt taaaaatgtt agaagaaaaa
     1681 atagaggctg gatataaaac ttttaaggta gagtcaagaa gaggagataa gtctttcgga
     1741 ttgacttctc aagaaatgag tatggatata ggtggatact tattatcaaa ggtaggagat
     1801 aggattaatg ttgatgtaag aaatccagaa gttaaaataa agtgcgaata cagagaattt
     1861 catactatgg tctatagtga tactatacct ggatatggtg gattgccact tggaacgaat
     1921 ggtagagcta tgtctctttt atcaggaggt atagatagcc cagtagctac atggatggtt
     1981 gcaaaaagag gtatggaagt agaggcagtt cactttcata gttatccatt tacaagtgaa
     2041 aggtcacagg aaaaagttaa ggatttagct aaaatactgg caaaatactg tggtagagta
     2101 aggcttcata aagttaatat cttagaaata caaaaagcaa ttggcgagaa ttgtaatgaa
     2161 gaagaaacta ctattctttc aagaagattt atgatgagga tagcacagag actttctgaa
     2221 aaaagacatt gtgatgcttt aattacaggt gaaagtattg ggcaggttgc atctcaaact
     2281 atacaagggc ttacttgtac taatgccgtt gtagacttac cagtgtttag accacttata
     2341 gcaatggata aatcagatat agttgatata gccaaaaaaa tagggacttt tgaaacatct
     2401 atagtgcctg aagaagattg ttgtagtgta ttttctccta gaaagcccgt cactaaacct
     2461 agattagaga aaatagaaaa atctgaaaca gcacttgaca ttgaaaaatt agtacaggat
     2521 gctattgaca aaatagaggt agaggatatt gagttttagc atacgagtta tttaattact
     2581 aaattgaata ttgagtatat tagtagttct gttgaaagga tttatgtaga caatttatta
     2641 atatgtagta tttaaaaata agtactataa ttttatttaa tgggaatgat tattatgaat
     2701 aaaaagggtt ttacattaat tgaattgttg gtagttatat ctataatagg aattttagtt
     2761 atagtagctg ttccagcgtt atttagaaat atagaaaaaa gtaaagcagt tacatgtctt
     2821 tctaatagag aaaatataaa gactcaaatt gttattgcaa tggctgagga atcaagtaaa
     2881 gacaagaatg aagtcataaa agaggtatta gaaaacaaag atggtaagta ctttgaaaca
     2941 gaaccaaagt gtaagtcagg tggaatatat tcagcaacgt ttgatgatgg ttatgatgga
     3001 ataactggaa tagaaagcat tgcaaaagtg tatgttacct gtacaaaaca tccagacggt
     3061 gttgaaatgg ctagggatgt acatcaaagt atgaaggatt tgattgcatc atttgcacaa
     3121 gacccttcta taataccagg agcttcaaag ggcaatgatg attttagaaa atatttatta
     3181 gacaataaat ataaaaatgg gtggcctaca attccagatg aatttaaggc aaaatatgga
     3241 ttaagtaagg atacactata tatacaacca tatgcatata atcctactaa atctgatgct
     3301 actgtagttg tatttgcaaa taataagact ggaggtaatt ggtatacttc cctagtttac
     3361 gattatgatg aaggtagatg gtataaaggt aaaaatggta tttctgttgc aggtaggtca
     3421 tgggatgttg acacagatag tgttaagtct gtaaaaacag agattcattc taaagaggga
     3481 tggggtcctt taaattaata taacatgttt tattaatctg gtattgatta aactatagaa
     3541 aagagcagtt tctatagatg acgaatacca gattttcatt tatatatata attgagatat
     3601 attaaaagtg tttatatttt taagtcttca catacaagct aaaaataatt ataataatat
     3661 tgtaaagaaa tttaattata agattaattt tctgaagatt tagtatttgt actaagaaat
     3721 acataaaaag gggaatagat atgaataata attttcaaga caaccaaaca ataaacttaa
     3781 tacaaagtcg tagaagtata cgaaaattta cgacagaaca aattagtgat gagcaagtaa
     3841 acacattatt acactgtgca tttgcagcac cttcaggatg taataaacag ccttggcaca
     3901 taactgttgt gcaagaccag aaacttttaa aagagattag tgatgatact ttatctagga
     3961 ttcatgaggt gagtaatgtt gagataaata aaaactttaa gttattttat agtgctccaa
     4021 ccgttttatt tatttcttat gatgaaagta gttcatgggc tccatatgat ataggaatac
     4081 ttacagggaa tataacaaca gctgcacaag cactagggct tggaagttgt ataataggaa
     4141 tggttagagg tttatttaca cctgttgaac aaggggatat tgaaggtctt gtgagtgtat
     4201 tggataaaga agatgtaaaa gaatcagagt caataaagat gaagtttgat acaaataaaa
     4261 aatacagaga actacttgat ataccagaag ggtattctgt accatttggt attgctgtag
     4321 gtattccaga tggaaattta ccaaatgcta gagaggtagt ttataaagtt tccagagttt
     4381 aggataaagt attgcaagaa acaatcagtt acttgaagaa ttaaatcagt aatatacaaa
     4441 taaattgatg gaagaggaag ctatttaaaa agtagtttag atttttcgtt gtaaaataat
     4501 taaataaaga ataaggtgat aagtatttta tttattatct tattcttttt tatttttgtt
     4561 ttgtagaatg ataaaaataa ggattaagtg taataaaata gaaaacaagt atgttaattt
     4621 taagtatatg ctttaaaatt tatccaagtt aaaaatttaa gatatctttt cagtataatg
     4681 gaaaaaatgt caaaatattg aaatagggaa aaaatagtga tataataaga aaaaatagag
     4741 aaaaaaagta accctt
//
LOCUS       DAFAZV010000114         4744 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFAZV010000114 DAFAZV010000000
VERSION     DAFAZV010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4744
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.117"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..165
                     /locus_tag="KOU88_003984"
     CDS             <1..165
                     /locus_tag="KOU88_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213793.1"
                     /translation="EEDKEFIQQILDFTGQKYSLHDDAPDISSEFINRINNIKVSETV
                     NIFDRKLLGF"
     gene            166..369
                     /locus_tag="KOU88_003985"
     CDS             166..369
                     /locus_tag="KOU88_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213794.1"
                     /translation="MGGNLLANRSKFEEVQKTLTKKGKKFNVGIGKDEKGYFAYTHRA
                     RSKSYISKQDIPIKVLKFIESTG"
     gene            382..1659
                     /locus_tag="KOU88_003986"
     CDS             382..1659
                     /locus_tag="KOU88_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213795.1"
                     /translation="MELDLDLIKDIYDDWNSNKSEYDTMYKYYKGETDAISNYKMVTK
                     RSNNKINTNFLKKFINEEVAYSLANKITYTSRSGDEKIINDLEYYTCHWSKKHDSDLL
                     RYALLFGLCYELYYVKDDEIQVKIIKPTDGCHYENENGEIVCFIREFTKGFEDDTYVD
                     VYDKEYIYHFDSNFKEVESPTVNNIFDGNVPISICKRSEELGKNTIFNDIKGLQDAYE
                     TNLSDISNEISDFRNAYLTFSGCNIKEDDLPRMKELGILQVNGDGKIEWLIKDMNDTF
                     VQNTLSSIKENMYEITSHINHNEKMQSNTSSLAVIARLISTEWICSQNNDSIADTLFN
                     RYKLLCIWLNKKYGFDYDYKDIKAKFTPKIPRDDLVVANILSQLGDKLSTETGLSQLS
                     FIDNPHAEIEKAKKEQEIVSEGEILLDESKDYN"
     gene            1637..2398
                     /locus_tag="KOU88_003987"
     CDS             1637..2398
                     /locus_tag="KOU88_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBK3213796.1"
                     /translation="MNQKIITKLTEDIYKSAENRTKPFYKYQRENRDKLLLEIAKILL
                     THDIINEYLNINNKDKKNLRSKLNKIINEYSNSYDEEVKDIETILSDSSKNKYSNLII
                     LLGVILKIKDVSNINNKVINKIVNNKVDGKHWSDRLWKNKKGIEESLKKEIKSFLNGK
                     TSVNKIEKAIRDKYSTGAGQTSRLIENEVARCQSEVNEYFFKVQGIIKVMYCADLDSR
                     TCSDCSMHNGVIFYVNEDRPSLPRHCHCRCQYIPV"
     gene            2457..2783
                     /locus_tag="KOU88_003988"
     CDS             2457..2783
                     /locus_tag="KOU88_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213797.1"
                     /translation="MKVEILGTEYLVIEKLESEDVLLKERAGYCDHSVKEIVIEKINS
                     EEGSLKDLSVYKNEVARHEIIHAFLSESGLKSCSSWATNEEMIDFFAIQFPKIVKVMD
                     KIECLN"
     gene            2809..3411
                     /locus_tag="KOU88_003989"
     CDS             2809..3411
                     /locus_tag="KOU88_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBK3213798.1"
                     /translation="MLKKEVLELLKEIEDDAEIDSLLQSTDLFKSASDKKLTIEEFRE
                     LINNDANFKAIIDNEKNKYHSEALENFKKKDMQTLISAEVLKRTGANETEEQKAIREL
                     RESLDKLKKEKQYAEKVSKYKDILVEKKIPTNLIEYLLSDDDDKTNANIEIFENSMKQ
                     YVQSKVDERIKDGSYVPPGKDSAGSLSEIRKQIKQGLNSL"
     gene            3440..4363
                     /locus_tag="KOU88_003990"
     CDS             3440..4363
                     /locus_tag="KOU88_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213799.1"
                     /translation="MANVLQYVTLFQQELDMQVTVGSTTGWMEKNAGQVIYNGGREVK
                     VPKVTMDGLGDYDRSKGYTQGAVTLEYETMKMEMDRGRTFMLDSMDVNESNFVINASS
                     VMGLFQKQHVIPEIDAYRYSKIFSETAKVDERVKYSYEATVTTILSELKNQLASIQDL
                     SGDIPLIISMSSIIASILEQSSQLDDIEFGDGDIKRIVKSIDNVPIIKVPSKRMKTEY
                     VFRDGKTSGQTEGGFTEGAKALDINWLITPASAPIAVSKTDKPRIFTPDQNQTADAYQ
                     IDYRKYHDLWILDEYLKLCRASVRQAKAAQE"
     gene            4377..4649
                     /locus_tag="KOU88_003991"
     CDS             4377..4649
                     /locus_tag="KOU88_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213800.1"
                     /translation="MFALIKNNIIKVVEDENSRDKLISKGFKIYSEEVTKENIEKKEE
                     KVKSTSNDLFNLSKPELMEIAKGKNIKGYSTKTKEELIQLLDEYNA"
     gene            4633..>4744
                     /locus_tag="KOU88_003992"
     CDS             4633..>4744
                     /locus_tag="KOU88_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HBK3213801.1"
                     /translation="MSTMLDNVKLVLGIENDRYDKLIILYINKISEMVLEY"
BASE COUNT         2012 a          492 c          849 g         1391 t
ORIGIN      
        1 gaagaagata aggaatttat acagcaaata cttgatttta caggacaaaa atactctcta
       61 catgatgatg ctccggatat atcatcggaa tttattaatc gaattaacaa cataaaagtt
      121 tctgagacag taaatatctt tgatagaaaa ttattaggtt tttagttggg aggtaattta
      181 ttggctaata gatcaaagtt tgaagaagtt caaaaaactt taactaaaaa aggaaagaag
      241 ttcaatgttg gaataggaaa agatgaaaaa ggatattttg catatactca tagagcaagg
      301 agtaaaagtt atatttcaaa gcaagatatt ccaataaaag ttttaaaatt tatagagtct
      361 acaggatagg atgtgttgtt aatggaatta gatttagact taataaaaga catatatgac
      421 gattggaact ctaataaatc cgaatatgat actatgtata agtattataa aggtgaaacg
      481 gatgctatta gcaactataa aatggttacc aagagatcta ataataagat aaacactaat
      541 ttcttaaaaa agtttattaa tgaagaagtc gcttattctc ttgcaaataa gattacctat
      601 acaagtagat ctggtgatga gaagattata aatgatttag aatactatac ttgccattgg
      661 agtaaaaaac atgactcaga tttattgagg tatgcactat tatttgggct ttgctatgaa
      721 ctttactatg taaaagatga tgaaatacaa gtaaagataa tcaagccaac agatggctgt
      781 cattatgaaa atgaaaatgg agaaatagta tgctttatta gagagtttac caaaggtttc
      841 gaagatgaca cgtatgtaga tgtatatgac aaagaatata tatatcattt tgattcaaat
      901 ttcaaagaag ttgaaagtcc tacagtaaac aatatatttg atggaaatgt tccaatatca
      961 atttgcaaaa gaagtgaaga actaggaaaa aatacaatat ttaatgatat aaaagggtta
     1021 caagatgctt atgaaactaa tttaagtgat ataagtaatg aaattagtga ttttagaaat
     1081 gcttatttaa ccttttctgg atgtaatatt aaagaagatg atttgccaag gatgaaagaa
     1141 cttggaatac ttcaagttaa tggagatgga aaaatagagt ggcttattaa agatatgaat
     1201 gatacatttg ttcaaaatac actatcttca ataaaagaaa atatgtatga aattacatct
     1261 catataaatc acaatgaaaa aatgcaaagt aatacatcaa gtctagcagt tatagcaaga
     1321 ttaatcagta cagaatggat ttgtagccaa aataatgata gtattgcaga tactttattt
     1381 aataggtaca aattattgtg catttggctt aataaaaaat atggttttga ctatgattat
     1441 aaagatatta aggctaaatt tacccctaag ataccacgtg atgatttagt tgtagcaaat
     1501 atattaagcc aacttggaga taaattatct actgaaactg gcttatctca actaagtttc
     1561 attgataatc ctcatgctga aatagaaaaa gctaaaaaag aacaggaaat agtttcagag
     1621 ggagagattt tattagatga atcaaaagat tataactaaa ttgactgaag atatatataa
     1681 atctgctgaa aataggacaa aaccatttta taagtatcaa agagaaaata gggataaact
     1741 tttattagaa atagcaaaga tattgctaac acacgatatt attaatgaat acttaaatat
     1801 taataataaa gataagaaaa atctaaggtc aaaacttaat aaaattataa atgagtattc
     1861 taatagttat gatgaagaag tcaaggatat agaaactatt ttatctgatt catctaagaa
     1921 taaatattca aatttgataa ttttattagg agtaatactg aagataaaag atgttagtaa
     1981 tataaacaat aaagttataa ataagatagt gaataataag gttgatggaa aacattggag
     2041 cgatagactc tggaagaata aaaaaggtat agaagagtcc ttaaaaaaag aaataaagag
     2101 ttttctaaat ggaaaaactt ctgtaaataa gatagaaaaa gcaataagag ataaatattc
     2161 aacaggtgca ggacaaacca gcagactaat agaaaatgaa gttgccagat gtcaaagtga
     2221 agtaaatgag tattttttca aggttcaagg gattataaaa gtaatgtatt gtgcagattt
     2281 agattctcgc acatgtagtg attgttctat gcataatgga gtgatatttt atgtcaatga
     2341 agataggccc tctttgccaa gacactgtca ctgtagatgt caatatatac ctgtttaaca
     2401 tgtattaatt aatttaatag gtgtttttat tatgtctaaa aaatatgagg tgaaatatga
     2461 aagttgaaat attaggaaca gaatatctag tgatagagaa acttgaaagc gaagatgtgc
     2521 tattaaagga aagagctgga tattgtgatc actctgttaa ggaaattgtt atagagaaaa
     2581 taaattctga agaaggttca ttgaaagatt taagtgtata taaaaatgaa gttgctaggc
     2641 atgaaataat tcatgcattt cttagtgaaa gtggattgaa gagttgtagt tcttgggcta
     2701 caaacgaaga aatgattgac ttctttgcaa ttcaatttcc taaaatagta aaggttatgg
     2761 ataaaataga atgtttgaat taaattttca aaaaggagaa ctttatacat gttaaaaaaa
     2821 gaagtgttgg aattactaaa agaaatagaa gatgatgcag aaatagattc attgctgcaa
     2881 tcaacagatt tattcaaatc tgcatctgat aaaaagctta caatagaaga gtttagagaa
     2941 ttaattaata atgatgcaaa ctttaaagct attatagata atgaaaaaaa taaatatcac
     3001 agcgaagcac ttgaaaactt taagaaaaaa gatatgcaga cacttataag tgctgaagtt
     3061 ctaaaaagaa ctggagcaaa tgaaacagaa gagcaaaaag caataaggga attaagagaa
     3121 agcctagaca aactaaaaaa agaaaagcag tacgcagaaa aagtttctaa atataaagat
     3181 attttagttg aaaagaaaat acctacaaac ttaattgaat atctattatc tgatgatgat
     3241 gataaaacaa atgcaaatat agagatattt gaaaattcaa tgaagcaata tgtgcagtca
     3301 aaggtagatg aaagaattaa agatggttca tacgttccac ctggcaaaga tagtgcaggt
     3361 tcgctatcag aaattagaaa acaaataaag caagggctaa atagtcttta gtataaaaaa
     3421 agaaaggatg attttataaa tggctaatgt attacaatat gtaacacttt ttcaacaaga
     3481 actagatatg caggtaacag ttggctcaac tactggatgg atggagaaaa atgctggtca
     3541 agttatatat aatggaggaa gagaggtaaa agtaccaaaa gtaacaatgg atggcttagg
     3601 tgattatgac agatctaaag gatatacgca aggcgcagtt acacttgagt acgaaacaat
     3661 gaaaatggag atggatagag gtaggacttt tatgttagat tcaatggatg taaatgaaag
     3721 taacttcgtt ataaatgcat cttctgtaat gggattattt caaaagcaac atgttatacc
     3781 agaaatagat gcatatagat actcaaagat attttctgaa acagctaaag tagatgagcg
     3841 tgtaaaatat tcatacgaag ctacagtaac tacaatatta agtgaattga aaaatcaact
     3901 tgcatcaata caagatttat ctggagatat acctcttatt attagtatgt ctagcataat
     3961 tgcaagcata ttagaacaat catctcaact tgatgatatt gaatttggcg atggagatat
     4021 aaaaagaatt gtaaagtcta tagacaatgt acctataata aaagttccat caaaaagaat
     4081 gaaaacagaa tacgtattta gagatggtaa aacatctgga caaacagagg gtgggtttac
     4141 tgaaggagca aaggctttag atataaactg gttaataact ccagcatctg ctccaattgc
     4201 agtatctaag actgataagc caagaatatt tactccagat caaaaccaaa cagcagatgc
     4261 ttatcaaata gactatagaa aatatcacga tttgtggata ttggatgaat atttaaaact
     4321 ttgtagagca tctgtgagac aagctaaagc tgcacaagaa taaggagttg ttttaaatgt
     4381 ttgcattgat aaaaaataac ataattaaag ttgttgaaga tgaaaattcg agagataaat
     4441 tgatttcaaa aggatttaaa atatattcag aagaagtgac taaagagaat attgagaaaa
     4501 aagaagaaaa agttaaatca acctctaatg atttatttaa tctatctaaa ccagagctta
     4561 tggaaattgc taaaggcaag aatataaagg gatattcaac taaaactaaa gaggaattaa
     4621 ttcaactact agatgagtac aatgcttgat aatgttaaat tagttttagg aatagaaaat
     4681 gatagatatg acaaattaat aatcctttat ataaataaaa taagtgagat ggttttagaa
     4741 tatt
//
LOCUS       DAFAZV010000115         4726 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFAZV010000115 DAFAZV010000000
VERSION     DAFAZV010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4726
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.118"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..126
                     /locus_tag="KOU88_003993"
     CDS             <1..126
                     /locus_tag="KOU88_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017143882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBK3213802.1"
                     /translation="LVKDFLLVSMGMGIGIVLMCILNIGKEADYEMKQLKESEDN"
     gene            868..2778
                     /gene="ltrA"
                     /locus_tag="KOU88_003994"
     CDS             868..2778
                     /gene="ltrA"
                     /locus_tag="KOU88_003994"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBK3213803.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGTPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMPDGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKTKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKTQKDKLVSQAKKI
                     ASPSKGKTELEEIRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGASKKG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYSANCYTPEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYVDNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTRAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            2945..3106
                     /locus_tag="KOU88_003995"
     CDS             2945..3106
                     /locus_tag="KOU88_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213804.1"
                     /translation="MAIVVIGIYLGFKREFSKLIGFLVVALIAVGLVFNAGGVKDVLL
                     ELFNKIIGA"
     gene            3316..3732
                     /locus_tag="KOU88_003996"
     CDS             3316..3732
                     /locus_tag="KOU88_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005428613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjdF family protein"
                     /protein_id="HBK3213805.1"
                     /translation="MKTIKCKLTVYFAEPFWVGVFERICDGKLSVAKVTFGAEPKDYD
                     IQEFVLKHYYDLQFSPAVETIVKKDKKNPKRVLRDVKKQLQNNGIGTKSQQALKLQHE
                     LKKEEYKSNSKHKKQMDAEQKFKLKQQKKKAKHRGH"
     gene            3975..4370
                     /locus_tag="KOU88_003997"
     CDS             3975..4370
                     /locus_tag="KOU88_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008393973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC family protein"
                     /protein_id="HBK3213806.1"
                     /translation="MAVSNINTIINNDIQKVWNIVLAVDKYNLWRSDLSKTEIINDKQ
                     FIEYTKNGYATTFTITVVEPYKRWEFDMENSNMKGHWIGVFTAKGNETQIDFTENVIP
                     KKWFMKPFVKTYLKKQQNQFVLDLKKALE"
     gene            4397..4717
                     /locus_tag="KOU88_003998"
     CDS             4397..4717
                     /locus_tag="KOU88_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
                     /protein_id="HBK3213807.1"
                     /translation="MASSKDYLQFVLEQLSELQEITYRAMMGEFIIYYRGKIVGGIYD
                     DRLLVKPTKSAISYMPTVTYEIPYENAKEMLLVEEVDNKDFLTGLFDVMYDELPTPKP
                     KKKK"
BASE COUNT         1810 a          681 c          958 g         1277 t
ORIGIN      
        1 ttagtaaaag acttcctgct ggtatctatg ggaatgggta tcggcatagt cttgatgtgt
       61 attttgaata tcggcaaaga agctgactat gaaatgaaac aattaaaaga aagcgaggac
      121 aattaaatga atttcggaca gaatttgtgt gcgactcgtt ccttagtgaa aagctaaggc
      181 actaataaaa gaacgaaaaa gtttgattat taggagaact gataatctga caggtggaat
      241 gatgaagtaa cgctctgaaa cgcctgccct gagcctccga caagcattga atgaggaaac
      301 tcagaatgtt tgaagctcgg taaagacggc tgaaagatac cgtaatagtt gatgaacata
      361 tatcttctat cgaaaactat ccagaggtgg gtagcgtatc caacaggtcg ggggtctata
      421 aaatatctat ggttagaatg ttccacaagg gactgacgaa acagcgaatg tacgggtcta
      481 aatttgtact tggtagaaat gcaaaggtac gagaaatcgt agctggtgtg gcaaagtaag
      541 aatataggtt atgaaatgcc atataccgtt acaggcggta tcaagccagc aggcttatag
      601 ctagtgacct aaggatatat atgtatagat aagattatcg gaacgaggaa aggtattggg
      661 ttctcatcaa gagaataagc tgacgaagaa caataagcag ttgaaccaat gctgaaaagc
      721 agagggcgaa cctaagaaat tcttgtaatg agaatggagg aataccctca agtcgtgtat
      781 atattagaaa agtattatgt tgttttaata aggattacga gtaagataaa aaagctcact
      841 caatttcaag caaaggagtg aagccttatg cctaaaaata aaaatgaaac attgtgtgta
      901 gaagatttaa gacacgctga atattacgaa atgcaaaaca cctttgatga tttatatgcc
      961 aaaagtaaga atggagatat tttcactcat cttatggata ttatcctatc gagagaaaat
     1021 atattactgg catatcgaaa tatcaaagca aatgcaggca gtaagacagc aggaacagac
     1081 ggtacaataa ttaaagatat tggcaaattg ccagcagaaa cagttgtcaa aaaggtaaga
     1141 tatattgtcg caggcactcc gcacgggtat cgacctaagc cagtaaggcg aaaagaaata
     1201 ccaaaaccaa atgggaaaac cagacctcta ggcattcctt gtatgtggga caggcttata
     1261 caacaatgta tcaaacaagt attagaacca atctgcgaag ctaaatttag tgaaaacagc
     1321 tacggtttca gacctaatag gtcggttgaa aatgcaataa aagcaaccta taaccgccta
     1381 caaatcagcc agctacatta tgtgattgaa tttgatatta agggcttctt tgacaacgtg
     1441 aaccattcca aactgataaa acagatatgg gctatgggaa tacgggacaa gcacttgata
     1501 ttcattttaa aaaggatatt aaaagctcca attaaaatgc ctgacggcac aataacatat
     1561 ccagagaaag gaactccaca ggggggaatt atatccccac tactagccaa cattgttctt
     1621 aatgagttag accattgggt agaaagtcaa tggcaggaaa atcctgttac aaaaaactat
     1681 gtggttcata tcaataaaag cggtagccca tgtaaaagca acgcttacaa agaaatgaag
     1741 aaaacaaagt taaaggaaat gtatatggtt cgttatgcag atgattttag agttttctgt
     1801 cgctacaaag aaagtgctga aaaaaccaaa atagcaatta ctcaatggat cgagcaacga
     1861 ctaaaattgg aagtatcaca agaaaaaaca agaattgtaa atgttagaaa aagatactcc
     1921 gactttcttg gtttcaagat taaaatgata ccgagaagaa agaagttagt tgttaaatca
     1981 catataagtg ataaacaatt caagacccaa aaagacaagc tggtatcaca ggcaaagaaa
     2041 attgcttctc cctcaaaggg aaaaacagaa ttagaggaaa taagacttta taattcaatg
     2101 gtattaggta tgcaaaatta ttatcagatt gcaacaaatg taaatctgga ttgtatgaaa
     2161 cttaatagag ctgtaatggc tatcttcact aacagattag gtgcaagcaa aaagggcaga
     2221 ttgagaaaaa caggcagaca acttacaaca aaagaagcaa caagatatgg taaatctaaa
     2281 atgcttcgat atgttgctgg cgagggcgaa cctatattcc ctgttggata tatccaacac
     2341 agaaaaccaa tggcaaaagt gtattcagca aactgctata ctccagaggg aagaaaattt
     2401 atccatacca atctaagtgt tgataaatta ctgatgtatc agttgatgaa attatctttg
     2461 gaaaatcgca caatagaata cgtagacaat cgaatttcgc tattttctgc ccaacatgga
     2521 aaatgtgcta taactctgga agaatttcaa caagctaatg aaatacactg tcatcatatt
     2581 gtaccaacta gggctggtgg taatgacgat tataaaaatc ttattttggt aaaagaggcg
     2641 gtacatcgtc taatacacgc aaaaacagaa gaaacaatac aaaaatatat agctctattg
     2701 aaactaaata aagtccagct cataagacta aataaatata gagtattagc tggcaatcaa
     2761 gaattaaact tgatataggt ctactacata aatacttttc aatataaaca cgatggaacg
     2821 cggagtgcgg tgaaagtcgc acgctccgtg tgaatggggg gaaaagtttg agatatttat
     2881 aatatcagga acttacctat ccatatatca atggttttta tcaaacgcac agagcttagt
     2941 gcttatggcg attgtggtta tcggtatcta cttagggttc aagcgtgagt tttcaaaact
     3001 tatcggcttc ttggtagtcg ccttgattgc tgtcggcttg gtattcaatg ctggcggtgt
     3061 gaaagatgta ctgttggagc tgttcaataa gattatcggt gcgtaaaatt ttattgtagt
     3121 gctgatatac gaatggtata attttcaaga aaggtaatca aataatgatt atctaaaatg
     3181 acaaagataa aaacgcaaag cattttatta tgtgagagct ggtaggtagc ccagccgtcc
     3241 tatgtttata gggtaagtaa cctgcccctc cgggttgtcc gttctttgtt tggaaataaa
     3301 caaggaggga ttgatatgaa gacaataaaa tgtaaattga ctgtgtattt tgcagaacct
     3361 ttttgggttg gagtttttga aagaatttgt gatggaaaac tttccgtagc aaaggtaaca
     3421 tttggtgcag agccaaaaga ttacgatatt caagaatttg tgttgaaaca ttattatgat
     3481 ttacaattta gtccagcagt tgaaacgatt gtaaaaaagg ataagaaaaa tcctaaaaga
     3541 gttcttagag atgtaaagaa acaattacag aacaatggaa ttgggacaaa atcgcaacaa
     3601 gctttaaaat tacaacatga attaaaaaaa gaagaatata aatctaattc caaacataaa
     3661 aagcaaatgg acgcagaaca aaagtttaag ttgaagcaac aaaagaaaaa agcaaaacac
     3721 agaggacatt aaatgatgtt gcaatatcat aaactaaata ttttataagt tcatatctac
     3781 acaaagcagt tagtcttatg attgactgct tttttcttgc caaaatttca gattggagtg
     3841 atgacatggt gtctgttaga gctgttcaat aagattatcg gagcataaaa ttttattgta
     3901 gtgctgatat gagaatgtta taatgtggat atgaaaaaac gataaacggt aatttaaaaa
     3961 gggggaatga aaaagtggca gtttcaaata taaatacaat tatcaataat gatattcaaa
     4021 aagtttggaa catcgtttta gctgttgata aatataactt atggcgaagt gatttgagca
     4081 aaacagaaat aataaatgac aaacaattta ttgaatacac aaaaaatgga tatgctacta
     4141 catttaccat taccgttgta gaaccatata aacgctggga atttgatatg gagaatagca
     4201 acatgaaagg tcattggatt ggtgttttta ctgctaaggg aaatgaaaca caaatagatt
     4261 ttacagagaa tgtgatacct aaaaagtggt ttatgaaacc ttttgtaaaa acttatttga
     4321 aaaagcaaca aaatcaattt gttctggact taaagaaagc attggaataa taaaatttaa
     4381 gattggaggg ttgtaaatgg cttcaagtaa agattattta caatttgttt tagaacaatt
     4441 atcagaatta caagaaataa catatcgtgc aatgatggga gaatttatta tctattatcg
     4501 tgggaaaatt gttggcggta tatatgatga taggttgctg gtaaaaccaa caaagtccgc
     4561 aatttcttat atgccaacag ttacttatga aattccatac gaaaatgcca aagaaatgtt
     4621 attggtggaa gaagttgata ataaagattt tctgacgggg ttatttgatg tgatgtatga
     4681 tgaactaccc acgccaaaac ctaaaaagaa aaaataaaca gcttct
//
LOCUS       DAFAZV010000116         4682 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFAZV010000116 DAFAZV010000000
VERSION     DAFAZV010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4682
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.119"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(843..1061)
                     /locus_tag="KOU88_003999"
     CDS             complement(843..1061)
                     /locus_tag="KOU88_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213808.1"
                     /translation="MSVLLKTKIKSYREKNLMTQGELAKSVGVRRETIVHLENGRYNP
                     SLKLAMDIAKVFDTTVEELFEFIEENNI"
     gene            complement(1062..1469)
                     /locus_tag="KOU88_004000"
     CDS             complement(1062..1469)
                     /locus_tag="KOU88_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213809.1"
                     /translation="MSKQQTGIKSTLISEILGISYCIGATLVNKYFFKGSSIEYLPII
                     IWVLAMGAQWVYNKKYDDLIDEASKCILSRVNDIAIKVLFFSVAIVSIFLVTLDINVS
                     NLNIGMSLLVILFIQSLLKLILFIYFDRKGIYN"
     gene            complement(1555..2043)
                     /locus_tag="KOU88_004001"
     CDS             complement(1555..2043)
                     /locus_tag="KOU88_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009892711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3841 domain-containing protein"
                     /protein_id="HBK3213810.1"
                     /translation="MKFYTIQTLEFWNNNKNNKYLSNDYSFILEDFDIPYKWMYSQMT
                     NRIYEFDDSMIWVWTKRPDLRCSGYLEKGKKGVLLEIEISEDNVLLSEFDLWHLPLMD
                     IAVELYEDEQIEKKVSWERIFDLELCSKLNEVNIEDLTLQGVTSKVPLSNVKLIKEFV
                     AK"
     gene            complement(2248..3369)
                     /locus_tag="KOU88_004002"
     CDS             complement(2248..3369)
                     /locus_tag="KOU88_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBK3213811.1"
                     /translation="MKEKLEEKSKIIKTSKEYKRTIIEEKDREWTKKLNDILSRGDFS
                     NEKLDKIKDLIPKEILTSENVGEVVTEDGYAKPEYDEVFKSLFTLNNDYDLLANFIND
                     ILKDAPYANRNIKQFTQIKRIIKVETDPTINYIGEKRPRLDILAEDEERNHINIEMQR
                     ALEEDYLERAEYYLSRVHGRKLEEGKEYKEIGKTVGIHILNHVKYNHIEDYVNCLRLT
                     MDGHPDIFSSKTALYFIELPKIRKSSCIANRVLIWGKLIDNPSHIDIRILSKTDYVIK
                     RALDRLKELGSNEDYLLNLKRGAYIMNKSRNFKEEIFQEGIEKGIEKGIEKGIAKGKR
                     EEKFNIIIKLKNKGYNLSEICDIIDDLNKSEVEKVYNQN"
     gene            complement(3742..3912)
                     /locus_tag="KOU88_004003"
     CDS             complement(3742..3912)
                     /locus_tag="KOU88_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003427864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213812.1"
                     /translation="MDSNNNTIKSTVKKGISFGSCLAMIISYTAWKSIPWAIFHGLMS
                     WIYVLYYWVKYA"
     gene            complement(4084..4527)
                     /locus_tag="KOU88_004004"
     CDS             complement(4084..4527)
                     /locus_tag="KOU88_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3213813.1"
                     /translation="MIEIKTIEINKKSQIDLLMLADPCEEMIDKYLNKGTMHALYDNK
                     ELTCIAVVNEISKEICELKNIATYEHFQNMGYASKMIYHLLDVYSKKYSSMVVGTSES
                     GVPFYEKFGFVYSHKIKNFFVDNYPEPIFEGELQCVDMLYLSYNF"
BASE COUNT         1569 a          743 c          408 g         1962 t
ORIGIN      
        1 ggaagtaatt tcatatttat ttaacttaat ttttttgtga taaaataatt ctaattttca
       61 tatagatatt attataaatt ttctagttta tggagtcatt cattctataa ttcacaaata
      121 tgtatttttt aatctattaa agtattcatt ttctggctta taagcatgga cttcttatct
      181 ataagcttgg tttttcatct aataagttat ttattcttta atctatgagc ttgatttttc
      241 atctataagt catttatttt ttaatctata agtttagttc ttcatctata aatcatttat
      301 tttttaatct ataagtttgg tttttcatct ataaataagt catttatttt ttaatctata
      361 agtttagttc ttcatctata aatcattcat tttttaatct ataagcttgg tttttaccta
      421 taattaattc attctctaat ctataagctt ggtttttatt tataagtcat ttattctcta
      481 atctataagc ttggttttta tttataagtc atttattctc taatctataa gcttacttct
      541 taatctataa gtcatttatt ctctaatcta taagcttact tcttaatcta taaatcattc
      601 attttttaat ctattagctt gttttttacc tataattaat tcattctcta atctataagc
      661 tttctttttc atctataaat cattcattct ttaatctatg agcttggttt ttcatctata
      721 agtcatttat tctctaatct ataagcttgg ttttttacct ataattaatt cattctctaa
      781 tacataaact tgaatttttt atctattaat tcattctcta atgcataagt aatacatgaa
      841 atttaaatat tattttcttc aataaattca aacaactctt ctacagttgt atcaaatacc
      901 ttagcaatat ccattgccag ttttaaagaa ggattgtagc gaccattttc taaatgtaca
      961 atagtttcac gtcttactcc tactgacttt gcaagttcac cttgtgtcat aaggttcttt
     1021 tctctatagg atttaatttt tgtctttagt aatactgaca cctaattgta tatccccttt
     1081 ctgtcaaaat atataaatag aattaacttc aacaaggatt gaataaacaa aatgactaat
     1141 aaagacattc ctatatttaa atttgacaca tttatgtcca aagttacaag aaatatagat
     1201 actatagcta cagaaaaaaa caatactttt attgcaatat cattaactct tgatagtata
     1261 cattttgatg cctcatcaat taaatcatca tactttttat tatagaccca ctgagctccc
     1321 atagctaata cccaaataat tataggaaga tattcaatac tacttccttt aaaaaaatac
     1381 ttatttacta atgtagctcc aatacaataa gaaattccca atatttctga aataagtgtt
     1441 gatttaatac cagtttgttg tttagacata taaaatcccc cttaaaaagt tatgtattta
     1501 taacacctct tgttataaat atataacttt tttgaataaa tttcaataaa aatattattt
     1561 tgcaacaaat tcttttatta attttacatt agatagaggc actttagatg tcactccttg
     1621 caatgtcaaa tcttctatat taacttcatt taattttgaa cacagttcta agtcaaatat
     1681 tctttcccaa cttaccttct tttcaatttg ttcatcttca taaagctcta cagcaatatc
     1741 cattaaaggt aaatgccata aatcaaattc tgataataac acattatctt cacttatttc
     1801 tatttcaagt aaaacacctt tttttccttt ttctaaataa ccactacatc ttaaatcagg
     1861 tctcttcgtc caaacccata tcatactatc atcaaattca tatattctat ttgtcatttg
     1921 actatacatc catttgtatg gaatatcaaa gtcttctaat ataaaagaat aatcatttga
     1981 tagatattta ttgtttttat tgttattcca aaattctaaa gtctgtatag tataaaattt
     2041 catatataaa tcaacccctt tgtttttcta taagaaggag atggttcaaa cttttatttt
     2101 gaattatctc ctttatttat acacctcttt gtacctatta tttatatatc tctttatatc
     2161 taccatattt aaatagcaaa gttttatatt aatttaaatt taaaagagga agctttgtat
     2221 ttatctagtg ccatctcaat catagtatta gttttgatta tagacttttt caacctctga
     2281 tttattcaaa tcatctataa tatcgcatat ttcactcaaa ttgtatcctt tattttttaa
     2341 ttttatgatg atattaaatt tctcttctct tttccctttt gcaatacctt tttcgatacc
     2401 tttttcgata cctttttcaa taccttcttg aaaaatttct tctttaaaat ttctactttt
     2461 attcataata tacgcacctc tctttaaatt taataaatag tcctcattac tacctaattc
     2521 ttttaatcta tcaagtgctc ttttaataac ataatccgtt ttagatagta ttctaatatc
     2581 tatatgagaa ggattatcaa taagtttacc ccatattaga actctatttg ctatacaact
     2641 ggatttacga atttttggaa gttctataaa atataatgca gttttactag aaaaaatatc
     2701 tggatgcccg tccattgtta atctcaggca atttacataa tcttctatgt gattatattt
     2761 tacatgattt agtatatgta ttccaacagt ttttccaatt tctttatatt ctttaccttc
     2821 ttctaacttt ctaccatgta cacgactaag ataatattca gctctttcca aataatcctc
     2881 ttcaagagct ctttgcatct caatatttat atggttacgt tcttcatctt cagccaaaat
     2941 atcaagtcta ggtcttttct caccaatgta attaattgtt gggtcggttt caaccttaat
     3001 tattcttttt atttgagtga actgtttgat attcctatta gcatatggag catctttgag
     3061 gatatcattt ataaaatttg caagtaaatc gtaatcatta tttaaagtaa acaatgattt
     3121 aaatacctca tcatactcag gcttagcata cccatcttca gttacaactt ctccaacatt
     3181 ttcactagtc aatatttctt ttggaattaa atccttgatt ttatctaatt tttcattaga
     3241 aaaatcacct ctactaagta tgtcatttaa ttttttggtc cattctctgt ccttttcttc
     3301 aattatagtt cgtttatact cttttgatgt tttaataatc ttagattttt cttctaattt
     3361 ttctttcata tcaacacctc ttttttatta ttacccattt cttcatacca aagtctgaac
     3421 ttctaagtaa aatttgcatt attgaaataa gaaccttata aacttatata tcattactaa
     3481 agttaagact ttaaagagaa gcacttagat tacaatagat tttagatagc tttcttttta
     3541 aaactattgt tgataaatga atgaatataa gggtatgtat taaaatagag atactcatct
     3601 ttttcattgt ttaaataatg aaaatatatt ttatttaata caaaaaagag tgccttataa
     3661 actaaaagtt cacttcgaga cactccctta cattttgttt cttaaacttt acaatattac
     3721 atacttattt attaatttaa tctatgcata cttaacccaa taataaagta catatatcca
     3781 actcattaag ccatgaaaaa tagcccatgg aatagatttc catgcagtat aagaaataat
     3841 cattgctaaa caagaaccaa aagaaatacc ctttttaaca gttgatttta tagtattatt
     3901 atttgaatcc ataattaatc ctccaaaatt caaaataaac aagttattat atatattatt
     3961 tgaatataat acaatgtaac agcttctaaa taaattatac tcttattata cataatttat
     4021 aaattataat tccgataatt atatgaatta attaattata ttaacctaaa aatattatcc
     4081 tatctaaaag ttatatgata gatacaacat gtcaacacat tgtaattctc cttcaaagat
     4141 tggttctgga taattatcta caaaaaagtt tttaatttta tgtgaataaa caaatccaaa
     4201 cttctcataa aaaggaactc cgctttcaga tgtaccaaca accattgatg aatatttttt
     4261 actataaaca tctaaaagat gataaatcat ctttgaggca taacccatat tttgaaaatg
     4321 ctcatatgta gcaatgtttt ttaattcaca tatttctttg gaaatttcat ttacaactgc
     4381 tatacaagta agttctttat tatcatacaa tgcgtgcata gttcctttat tgagatattt
     4441 atcaatcatt tcttcacatg ggtcggctaa cattaaaagg tcaatttgac tttttttatt
     4501 tatttctata gtttttattt ctatcataag ttctccaccc tcactttatt caaaccttaa
     4561 tttaacaaac ttcttacagt acttatttag ttcattttga tatatatttt tactttttaa
     4621 aatatagtga taattcccta gaatattaat actaataata aattataata tcagctctag
     4681 ca
//
LOCUS       DAFAZV010000117         4666 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFAZV010000117 DAFAZV010000000
VERSION     DAFAZV010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4666
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.120"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            231..1310
                     /locus_tag="KOU88_004005"
     CDS             231..1310
                     /locus_tag="KOU88_004005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBK3213814.1"
                     /translation="MPELLKNMYNRESLYEVAVAIQSVYNSFKVDEFIKSTMDETWNN
                     LELKARCRKISMSLGMYLPEDYKEALSILEKSVTGFYFAFFFPDFVEVYGQDDINWDL
                     SISALERNTEYWSSEFAVRAFIIKDEERMMAQMRKWSKHKSEHVRRLASEGCRPQLPW
                     GQAISKFKKDPTPVLPILEQLKTDTSTYVQKSVANNLNDISKTHPDLVISIVKDWYGK
                     NKSTNWIVKHGCRTLLKKGNRDVLALFGYDDTTSINLQDFTLETTSISIGEDLTFSFN
                     ILAKKATKTRLEYGIDYIKSNGKRNRKIFKISEVSLKENEKKSYMKKHSFADVSVRKH
                     YPGIHSIAIIINGIEKDKLDFELGI"
     gene            1634..2002
                     /locus_tag="KOU88_004006"
     CDS             1634..2002
                     /locus_tag="KOU88_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HBK3213815.1"
                     /translation="MDVYSFWNDTLAQDAVKIRKYFHENAYINWHDTNEHFTLEEFII
                     ANCEYPDKWNGKVEKVLEFGNLVITVTHVYAINKPLSFHVVSFISLKDDKIISIDEYW
                     GEDDDVPQWRLDKHIGKPIK"
     gene            2119..2916
                     /locus_tag="KOU88_004007"
     CDS             2119..2916
                     /locus_tag="KOU88_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3213816.1"
                     /translation="MEEKYILSDRGKVYYWIKESNSVFAKNLIFLPGLTANHHLFDFQ
                     IQYFSKNHNVLVWDAPAHGKSRPYLDFSYSNLVEELKVILDKQNMKKVVLIGQSAGGF
                     VAQSFIVKYPNMVEGLMMIGTCPYGTDYYSKSDIFWLKQTEWMLKLFPDKFLRNIISK
                     MCGATSEGRRSMLKMLEGYEKKELCHLMYLGFAGFIPEIQDLNIHCPVCLVVGDKDKT
                     GKVRKYNEQWHNKTGYPLHIIKNASHNVNVDKPNELNQIMDIFIKQL"
     gene            3315..4205
                     /locus_tag="KOU88_004008"
     CDS             3315..4205
                     /locus_tag="KOU88_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3213817.1"
                     /translation="MIESIPAKQILQKVKFDNTRWFGIDYNMNLYRGCSHGCIYCDSR
                     STIYNIENFDKVRYKENVIEILSKELRSKRKKGVVGIGAMSDTYNPFEKQLCITKQAL
                     DLISENHFGVSIDTKSSLVVRDIPILQKIKKNNSAIVKLTITTANDELSKKIEPYVNP
                     SSVRFEAVKELNDSGIFCGILLTPMLPFLTDNKDEIRAIVEKAHKANAKFIYCMYGVT
                     MRSGQREFFYEHLRDISPKLVLKYQKTYGLNYVCTVQNKDCCEKLLREECARYGILTD
                     MKEIIKAYKRSESYIQIKFF"
BASE COUNT         1773 a          500 c          876 g         1517 t
ORIGIN      
        1 cagtaaagta taaaattcta ttactataat aaaagataga actagaagtc tttatgaaag
       61 tgggaaaagt atttatataa ataaattcat atagtttata gtttaatagt aggaaatatc
      121 gtatgagtaa gaatattgta ttttacataa agatttagca atatgacaca ctgttgtcgt
      181 gttctgtagg atatgattaa taaatcagat atgaaaggag agtgagtaat atgccagaat
      241 tactaaaaaa tatgtataat cgtgagtcac tttatgaagt tgcagtagct atccaatcag
      301 tttacaactc atttaaggta gacgagttca taaaatctac aatggatgag acatggaata
      361 acttagaatt aaaagccaga tgtcgaaaga taagcatgag tttaggaatg tatttaccag
      421 aagactataa ggaagctctt tccattcttg aaaaatcagt tacaggtttt tattttgctt
      481 ttttctttcc agattttgtt gaagtttatg ggcaggacga cataaattgg gatttatcta
      541 taagtgcatt agaaagaaat actgagtatt ggtcttcaga atttgctgta agagccttta
      601 tcatcaagga cgaagagcgt atgatggcac agatgcgtaa atggtctaag cataagagcg
      661 aacatgtacg aagacttgca agtgaaggct gtcgtcccca gttgccttgg ggacaagcaa
      721 tatccaaatt taaaaaagac cctacacccg tactgcctat attggagcaa cttaaaacag
      781 atacatcaac gtatgtacaa aagagtgttg ctaataatct aaatgatatc tcaaaaacac
      841 atccagattt agtcataagc attgtaaagg attggtacgg taaaaataaa tccactaact
      901 ggattgtaaa gcatggttgc agaactctac taaaaaaagg caatcgtgat gtattagccc
      961 tttttggata tgatgatact acttctataa atcttcagga ctttacttta gaaacaacgt
     1021 ctatttctat tggagaggat ttaacttttt catttaatat tttagcaaaa aaagcgacaa
     1081 aaacaaggct cgagtacgga attgattata ttaaatctaa tggaaaaagg aataggaaga
     1141 tatttaaaat atcggaggtt tcattaaaag aaaatgagaa aaagtcatat atgaaaaaac
     1201 attcatttgc agatgtaagt gtaaggaaac attatccagg tatacactcg attgctatta
     1261 ttattaatgg tatagaaaaa gataaacttg attttgaatt aggtatataa ttttactaac
     1321 agaataatct atatcagata ctttgctaaa cttatataat atattttact aaatttatat
     1381 taggtagttt actacttgtt tactgaattt aaatacaaag aaatacaggt gctaatccct
     1441 gcccattaaa ggaatatgag cataacacaa aagtagaact tatcaattct gttacgggta
     1501 tagtagtaaa tccatagaat cacaattaga agatgaagtg taaaaaataa gttagtgttg
     1561 attttagttg ctagtgatat tgaatagtta tacaatagct atataaatta gaatttgtag
     1621 aggagaaatg taaatggatg tatatagttt ttggaatgac actttagcac aagatgctgt
     1681 taagataaga aaatattttc atgaaaatgc ttatattaat tggcatgata caaatgagca
     1741 ttttacttta gaagaattta ttattgcaaa ttgtgagtat cctgataaat ggaatggtaa
     1801 agtagaaaag gtgctagaat ttggaaattt agtaattaca gtgacacatg tttatgcaat
     1861 aaataaacca ctatcatttc atgtcgtttc atttatcagc cttaaagatg ataagattat
     1921 ttctattgat gaatattggg gagaggatga tgatgtgcca cagtggagat tagataaaca
     1981 tattggaaag ccaataaaat agtgtttgtt ctgttttata actgaaattt tgataacatt
     2041 tgatactttg atttgtcatt ggtcaacata gtcgttagtg taataattta aaaaagtaga
     2101 atttggagag tgagcactat ggaagaaaaa tacatcttat ctgaccgagg taaagtatat
     2161 tattggataa aagaaagtaa tagtgtgttt gcaaagaact taattttttt gccaggacta
     2221 acagcaaatc atcatctttt tgatttccag atacagtact tttcaaaaaa tcataatgta
     2281 ttagtatggg acgctcctgc tcatggaaaa tcaagacctt acttagattt ctcatattct
     2341 aacttggtag aagaattgaa agtaatttta gataaacaaa atatgaaaaa ggttgtactt
     2401 atagggcaat cggcaggggg atttgtggca cagtccttta ttgtaaaata tccaaatatg
     2461 gtagaaggac taatgatgat tggaacttgt ccatatggaa ctgactatta tagtaagtca
     2521 gatattttct ggttaaaaca gactgaatgg atgttaaagt tattcccaga taaatttttg
     2581 cgaaacataa tatctaagat gtgtggagct acgtctgaag gcagaaggag tatgctgaaa
     2641 atgttagaag gctacgaaaa aaaagaactg tgtcatctca tgtatctggg atttgctggg
     2701 ttcataccag aaattcaaga cttaaatata cattgtccag tttgtttggt ggttggagat
     2761 aaagacaaga cgggtaaagt gagaaaatat aatgagcagt ggcacaataa gactgggtat
     2821 ccattgcaca ttataaaaaa tgcttcacat aatgtaaatg tcgataaacc taatgaacta
     2881 aatcagatta tggatatatt tattaagcaa ttataatata taaaaattac atacccatta
     2941 ggtaaattat gtagtatatg tgtttacaga tggttataga aataaatatg taataaacta
     3001 cttaacactt aaaaagtgga tttgtccaga gtataataca aagcatgata tatataaatt
     3061 tttaagcgaa atacatcaaa agaaggatta gaattagtgg agacagaaca gctattatag
     3121 attataaata aatagtttta aaggagaggt actacgaata tagaggaagg taaatcatac
     3181 gttattcaag tattataaat gattagttta aaagtactat cgaataggag tctccatatt
     3241 taaaccttag taaaggtagt taaagtagta gtttaaaaac taaaaaatta tataaaggaa
     3301 ttaggtataa gaaaatgatt gagagtatac cagcaaaaca aattttacaa aaagtgaaat
     3361 ttgacaatac aagatggttt ggaattgact ataatatgaa tctctatcgt ggttgttctc
     3421 atggatgtat atattgtgat agccgtagca caatatacaa catagagaat tttgacaaag
     3481 ttagatataa agaaaatgtg atagaaattt taagtaaaga attgcgttca aaaagaaaaa
     3541 aaggggtagt aggcattgga gctatgtctg acacatataa tccttttgaa aagcaacttt
     3601 gtattacaaa gcaggcacta gatttgattt cggaaaatca ttttggagtg tctattgata
     3661 ctaaaagtag tttggtggtt agagatatac cgattttgca gaaaattaaa aaaaataatt
     3721 ctgctattgt aaagttgact ataaccactg caaatgatga attatcaaag aaaatagaac
     3781 cttatgtaaa tccaagttct gtacgatttg aggcagtgaa agaacttaat gattctggaa
     3841 ttttttgtgg tatattattg actcctatgc ttccattttt gactgataat aaagatgaaa
     3901 tacgagcaat tgtagaaaaa gcacacaagg ctaatgcaaa atttatttat tgcatgtatg
     3961 gtgtaacaat gcgtagtggt cagagagagt ttttttatga gcatttaaga gatatatcac
     4021 caaaattggt acttaaatat cagaaaacat atggtttaaa ctatgtatgt actgtacaaa
     4081 ataaagattg ttgtgagaag ttgttaagag aagaatgtgc acgttatggt attttgacgg
     4141 atatgaaaga gattataaaa gcgtacaaga ggtcggagtc atatattcaa ataaaatttt
     4201 tttaagatag gctttggatg agatataata gtggtgattg atgtgttgat attatagttg
     4261 attgttagag aggatattat agatgaatat tagtattgat attttaggta attgctagag
     4321 ctgatattat agatgaatat tagtattgat attctaggta attgctagag ttagtattat
     4381 agatgaatat tagtattgat attctaggta actgctagag ctaatattat agatgaatat
     4441 tagtattgat attctaggta attgctagag ctaatattat agataaatat tagtattgat
     4501 attctaggta attgctagag ctgatattat agatgaatat tagtattgat attctaggta
     4561 actgctagag ctaatattat agatgaatat taatattgat attctaggta attgctagag
     4621 ctgatattat agatgaatat taatattgat attctaggta attgct
//
LOCUS       DAFAZV010000118         4603 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.121, whole genome shotgun sequence.
ACCESSION   DAFAZV010000118 DAFAZV010000000
VERSION     DAFAZV010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 4603)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4603)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4603
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.121"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..468
                     /locus_tag="KOU88_004009"
     CDS             <1..468
                     /locus_tag="KOU88_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HBK3213818.1"
                     /translation="WELYEKLVDGYFSMRKELNNPLLSASKELQAIFMLDKKQEVLET
                     KIENVNEKLENFMDDAPLFNIECECIVKEVKRVATKSLGGHGSKAYKNKSLRGKVYSD
                     IYHQIKREFGVDSYKAIKRCQLDKVLEIVNSYKLPIVFEEEIRLLNSQLSIVS"
     gene            611..1099
                     /locus_tag="KOU88_004010"
     CDS             611..1099
                     /locus_tag="KOU88_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213819.1"
                     /translation="MDNNINKKELFKKVEGRLHHYKFLSAEIKNLELDIESRENEIFG
                     CKAIGYGEKVSPTYAFNSTVENEIIKKERDIARLKKLKKDKEIEKKKIENALTCLDIR
                     EEHFFKLFYNSRMKNSMVYISLEMNSDRKTCRCVRERLVYKVMDMLYPRIKENELPLF
                     KN"
     gene            1681..2358
                     /locus_tag="KOU88_004011"
     CDS             1681..2358
                     /locus_tag="KOU88_004011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015994390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bro-N domain-containing protein"
                     /protein_id="HBK3213820.1"
                     /translation="MLKILQEKNVKVMWSKNGEEVWFNANDVGEELGIVNIRDTLRNI
                     DREYKKKFNESTVGDSYTRNFKDKLPNFGTTFVTEEAVYNMSFRSNKPEAKLFTKWVT
                     KTLKQIRIHGYYIATEKDQEWLDIRTEGKKVRKDFTDEIQEFVYYATSQGSNKPQMYY
                     KHFTELVRKKLGIPKGVKRDELNQSELFDIQALERIISMKLPKLIDKDMNYKEVYKKI
                     KELIEMI"
     gene            2421..3101
                     /locus_tag="KOU88_004012"
     CDS             2421..3101
                     /locus_tag="KOU88_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213821.1"
                     /translation="MQDVKEKVKQDYIKGMKQKEISAKYDISLNTLKSWIKRYNWASE
                     KKKGAPKNKRGAPIGNKNATGPPGNKNAEKFGFFSKYLPEETRELIQEISIKDKFDIL
                     WEQITIQYAAIIRAQKIMYVKDKEEMIKELKKHESTENGEKIEYEFQFAWDRQASFLN
                     AQSRAMSELRSLIKQYDEMIHKDWNLATEEQRARVEVLKSKINNQESKEDKLDRYFDK
                     LESVIKND"
     gene            3094..4323
                     /locus_tag="KOU88_004013"
     CDS             3094..4323
                     /locus_tag="KOU88_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003453662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HBK3213822.1"
                     /translation="MIDELYHSKQLEVLNFALNNDYFMLINYGAKRTGKTIIDNDLFL
                     LELRRVRKIANELGIKLPQYILAGADLGALQRNVLSELTNKYDIEFKFDKHNRFVLFG
                     VQVCCFGHSKTNDLGRIRGMTSFGAYINEGTVANEEVFNEIKSRCSGEGARILVDTNP
                     DQPEHWLKTNFVDKTDGKVIQSFHYKLDDNIFLSERYRANIKKSTPSGVFYDRDINGL
                     WVSADGLVYQDFNKDIHYISKDKLNDINFVRYFAGVDWGYEHFGAIVVIGEDDKGNLY
                     LLEEHSAQHKEIDYWIDKAKSIKEKYGNIKFYCDSARPEHLAAFKRNGIKAFNANKAV
                     LSGVEAVAKRIKTNTLFVVHENVNLFRKEIFMYAWNKNTGEPIKKWDDVLDALRYAIY
                     TDSLGTGIKVLTPNGRR"
     gene            4328..>4603
                     /locus_tag="KOU88_004014"
     CDS             4328..>4603
                     /locus_tag="KOU88_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213823.1"
                     /translation="MELDVIKKLIEQTNSKHSNFVKKADEAEKYYKNENDIIRDRSPN
                     NIGKVNTTNNPLRNADNRIPFNWFGFLVNQKISYLFTYPPTFDVGDDR"
BASE COUNT         1875 a          502 c          865 g         1361 t
ORIGIN      
        1 tgggaattat atgagaagtt agttgatgga tatttctcta tgagaaaaga actaaataat
       61 cctcttttaa gtgcatcaaa ggagttacaa gctatattta tgctagataa gaaacaagaa
      121 gtcttagaaa ctaaaataga gaatgttaat gagaagttag agaactttat ggatgatgca
      181 ccattattca atatcgagtg tgagtgtatt gttaaagagg ttaagagagt agcaacaaaa
      241 tcacttggtg gacatggaag taaggcttat aaaaataaat ctttaagagg taaagtttat
      301 agtgatatat accatcagat taaacgagaa tttggagtag atagttataa ggctataaag
      361 cgttgtcaat tagataaagt attagagatt gtaaatagtt ataagttacc tatagtgttt
      421 gaagaagaaa taagactttt gaatagtcaa ttatcaattg tgagttaaga caggaataga
      481 tttttctcct ttaaagggga aaacctgcaa tagttaatta aaagagaaaa ggagtgcttt
      541 cacactccac ttgtcaaaaa tataaagctt ttatccaaga ttattataac ataaacagga
      601 gtgtgaaagt atggataata atattaataa aaaagaacta tttaaaaaag tagaaggtag
      661 actacatcat tataaatttt taagtgcaga aattaaaaat cttgaattag atatagaaag
      721 tagagaaaat gaaatatttg gttgtaaggc tatcgggtat ggtgaaaaag taagtccaac
      781 atatgctttt aattcaactg ttgagaatga gattataaaa aaagaaagag atattgctag
      841 attaaaaaaa ctgaaaaaag ataaagaaat agaaaagaag aaaatagaaa atgcacttac
      901 atgcttagat ataagagaag aacatttttt taaactgttt tataatagca gaatgaaaaa
      961 tagtatggtt tatatatcct tagaaatgaa ctcagatagg aaaacatgta gatgtgtaag
     1021 ggaaagatta gtgtataaag ttatggatat gctttatcca agaattaagg aaaatgaact
     1081 cccattattt aaaaattaga aaattcccca gtttttcccc agaaattccc actttattcc
     1141 ctactttctc cccgttttga ttaaaaaagc atgagataat agtattgtgg aaataaagat
     1201 ttccctctca aaacttaata tttgactagg gttaagggat tgccctagtc actatgaaca
     1261 gactaggcag ggcatgagga tgctgttagt tcaattctaa ctatgttcaa tctttagttt
     1321 ttctatttca attaatctac ggatacacta aaaaatagta tatgaattga gattaaaatc
     1381 tcatacaatt ttgtatctta attcaaagtc taaaaaccga gtggggcttg gtaacctcac
     1441 tcaccatgca agtactggtt taatctaggt tcgattcctg gaacttgctc cctttaataa
     1501 tatgtatccc ccattaaaaa ggcttagatt aacttctagg tcttttttaa tacaaaaatt
     1561 tattaaaaat gcacggcatg cactattcag atatgcatgt catgcatgtc taaagtcgaa
     1621 tatttaatat tttcgatggc tcaaattgag gggtcgaaaa taaaaacagg aggtagtagt
     1681 atgttgaaaa ttttacaaga gaaaaatgta aaagtaatgt ggtccaaaaa tggagaagaa
     1741 gtttggttta atgcaaatga cgtaggagag gaactaggca tagtaaatat tcgtgataca
     1801 ttaagaaata tagatagaga atataaaaag aaatttaatg agtctactgt cggagattcc
     1861 tacactagaa actttaaaga taaattgcct aacttcggta ctacttttgt tacagaagaa
     1921 gctgtgtaca atatgtcatt tagaagtaat aaaccagaag caaagttatt tacaaaatgg
     1981 gttacaaaaa cacttaaaca aattagaata catggttatt atattgctac agaaaaagac
     2041 caggaatggc tggatataag gacagaaggc aaaaaagtaa gaaaagattt tacagatgaa
     2101 atacaagagt ttgtatatta tgctactagt caaggtagca ataaacctca gatgtattat
     2161 aaacatttta ctgaacttgt aagaaaaaaa ttaggtattc caaaaggtgt gaaaagagat
     2221 gagttaaatc aaagcgaact atttgatata caagcacttg aaagaattat atctatgaaa
     2281 ttacctaagt taatagataa agatatgaat tataaagagg tatataaaaa gattaaggaa
     2341 ttaatagaaa tgatttaagg gactgtcttg atggagggtc ttttttaatt cccaaaacga
     2401 caaacaaacg aggtggtgat gtgcaagatg tcaaagaaaa ggtaaaacaa gattacataa
     2461 aaggtatgaa acaaaaggaa atatcagcaa agtatgacat tagtttaaac actttaaagt
     2521 catggataaa aagatacaat tgggctagtg agaaaaagaa gggtgcacct aaaaataaaa
     2581 gaggtgcacc cataggtaat aaaaatgcca ctggtcctcc tggaaataaa aatgctgaaa
     2641 agtttggttt cttctcaaaa tatctacctg aagaaactag ggaattaata caagaaatat
     2701 ctataaaaga taaatttgat attctttggg aacagataac aattcaatat gcagcaataa
     2761 taagagcaca aaagataatg tatgttaaag acaaggaaga aatgattaag gagttaaaga
     2821 aacatgaaag cacagaaaat ggtgagaaga tagagtatga atttcaattt gcatgggata
     2881 ggcaagcatc ttttcttaat gcacagagta gggctatgag tgagttaagg agtttaatta
     2941 aacaatatga tgaaatgatt cataaggatt ggaatttagc tacagaggag caaagagcaa
     3001 gagtagaagt attaaaatca aagataaata atcaagaaag taaagaagat aaacttgata
     3061 gatattttga taaactcgaa agtgtgataa aaaatgattg atgaattata tcatagtaaa
     3121 caacttgaag ttcttaactt tgctttgaat aatgactact tcatgctaat taattatggt
     3181 gctaaaagaa caggaaaaac aataattgac aatgatttat tcttacttga acttagaagg
     3241 gttagaaaga tagctaatga gctaggtatt aagcttcctc aatacatctt agcaggagca
     3301 gatttaggag ctttacaaag aaatgtacta agtgagctta caaataagta tgacattgag
     3361 tttaagtttg acaaacataa tagatttgta ttgtttggag ttcaagtatg ttgctttgga
     3421 cactcaaaaa caaatgattt aggcagaata agaggtatga cttcgtttgg ggcatacata
     3481 aatgaaggta cagttgcaaa tgaagaagta tttaatgaaa tcaaatcaag atgtagtgga
     3541 gaaggtgcta gaatacttgt agatactaac ccagaccaac cagagcattg gttaaaaact
     3601 aactttgtag ataaaacaga tggcaaggtt attcaatctt ttcattacaa attagatgat
     3661 aatatatttt taagtgaaag atacagagca aatattaaga agtctactcc tagtggcgtt
     3721 ttttatgaca gagatataaa tggtttatgg gtgtcagcag atggattagt ttatcaagat
     3781 tttaataagg atattcatta tatttctaag gataaattaa atgatattaa ttttgtaaga
     3841 tactttgcag gcgttgattg gggatatgaa cattttggag ctattgttgt aattggagaa
     3901 gatgataaag gtaacttata tttattagaa gaacattcag ctcaacataa ggaaatagat
     3961 tactggatag ataaggctaa aagtataaaa gaaaagtatg gaaatataaa gttttattgt
     4021 gatagtgcta gacccgaaca tttggcagca tttaaaagaa atggtataaa agcttttaat
     4081 gctaataaag ctgtattgtc tggcgttgaa gctgtagcta aaagaattaa aactaatact
     4141 ttatttgtag ttcatgagaa tgttaattta ttcaggaaag aaatttttat gtatgcttgg
     4201 aataaaaata caggtgagcc aattaaaaag tgggatgatg tattagacgc acttagatat
     4261 gccatctata cagattcctt aggaacagga attaaagtac ttacaccaaa tggaagaagg
     4321 tgataaattg gaattagatg taataaaaaa gttaattgaa caaactaata gtaaacatag
     4381 taactttgtt aaaaaagctg atgaagctga aaaatactat aaaaatgaaa atgacattat
     4441 aagggataga agccctaata atattggaaa agtaaataca actaataatc cactaagaaa
     4501 tgcagataat agaataccat ttaattggtt tggtttttta gttaaccaaa aaatatcata
     4561 tctgtttact tatccaccta catttgatgt tggagatgat aga
//
LOCUS       DAFAZV010000119         3981 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFAZV010000119 DAFAZV010000000
VERSION     DAFAZV010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3981
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.122"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            162..299
                     /locus_tag="KOU88_004015"
     CDS             162..299
                     /locus_tag="KOU88_004015"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213824.1"
                     /translation="MGNSDCSKMLAFYEIMKMLETIDEAKFYNCKEEIKSEFKHIKKE
                     D"
     gene            complement(327..719)
                     /locus_tag="KOU88_004016"
     CDS             complement(327..719)
                     /locus_tag="KOU88_004016"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213825.1"
                     /translation="MYKDESNIFSKRLREEREELGLMQKEMANKLSLPANTYNGYETG
                     KRSPALDVVRHIADTLDISTDYLLGRTNIKINISNITEKELIKKLNPSDDMKEILDIF
                     SELDDDSKNKALKIAKLFLEEQNTKNKE"
     gene            908..1102
                     /locus_tag="KOU88_004017"
     CDS             908..1102
                     /locus_tag="KOU88_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008422227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213826.1"
                     /translation="MKNYILKSLRVRQGLRQRDLAKILGMNPSTYSSKENGDRRFTVS
                     EAIKISDFFNTDLRDIFLNK"
     gene            1138..1929
                     /locus_tag="KOU88_004018"
     CDS             1138..1929
                     /locus_tag="KOU88_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6N domain-containing protein"
                     /protein_id="HBK3213827.1"
                     /translation="MNNLQVIERNNKRVLTTQQLADVYETDARNISNNFNNNKDRFIE
                     GKHYFCLQGDDLRIFKRGSYDIGIAPNVNKLYLWTERGANRHCKILDTDKAWEQFDNL
                     EETYFKVKQQKLTCIEDVLIESLKEMKDLRLQVNQANNIALEAKTEVKTIKEVVSLNA
                     TDWRKDTQQLIARIAKKQGGFEHINMLRRESYELLNKRFGVDLHRRLINKRRKMAEEG
                     VSESKREKVNNLDVIQDDKKLIEGYVAIVKDMALKYGISSDLSKN"
     gene            1991..2158
                     /locus_tag="KOU88_004019"
     CDS             1991..2158
                     /locus_tag="KOU88_004019"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213828.1"
                     /translation="MENKKIEEIKNALIGVNQIEWSLVKSFIDMYFSKKAAKLEIDDL
                     DNFDLYIKRKF"
     gene            complement(2155..2394)
                     /locus_tag="KOU88_004020"
     CDS             complement(2155..2394)
                     /locus_tag="KOU88_004020"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213829.1"
                     /translation="MTKIYACLAGNWVNLCDDPECKMGSNHSSPYIWWEEGADVWSPS
                     NKEEEHTMYQQDYVHIYYKGVDYRIHPIFIQIASN"
     gene            2470..2667
                     /locus_tag="KOU88_004021"
     CDS             2470..2667
                     /locus_tag="KOU88_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213830.1"
                     /translation="MLIGDNISQILRKRNIKPYKLAKELGIDESGLYKIIRNEKKNPT
                     INTLIKIADYLDVTLDELVGR"
     gene            2706..2915
                     /locus_tag="KOU88_004022"
     CDS             2706..2915
                     /locus_tag="KOU88_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213831.1"
                     /translation="MAKAVAKEPLFYRAKDVAKFLDICEATAYKIIAELNEELEKEGF
                     KTFSGRVSVAYFKERYCYKPRKGVI"
     gene            2916..3056
                     /locus_tag="KOU88_004023"
     CDS             2916..3056
                     /locus_tag="KOU88_004023"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213832.1"
                     /translation="MNVRVLIAYIQFCNDKQIKASFEGLRKYNRDIELVNLYLPAHLK
                     IK"
     gene            3088..3228
                     /locus_tag="KOU88_004024"
     CDS             3088..3228
                     /locus_tag="KOU88_004024"
                     /inference="COORDINATES: protein motif:HMM:NF015807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBK3213833.1"
                     /translation="MQREQTTIRLPKELKEKLEKQASKKGRSFNSILLSILQEFIQNP
                     NV"
     gene            complement(3206..3394)
                     /locus_tag="KOU88_004025"
     CDS             complement(3206..3394)
                     /locus_tag="KOU88_004025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Arc family DNA-binding protein"
                     /protein_id="HBK3213834.1"
                     /translation="MAKMGTYKNPHFAIRIPKEKLDKLKYIAEYNARSANKEIEFLVT
                     KHIEMFEKEHGPIHLDSE"
     gene            3550..3708
                     /locus_tag="KOU88_004026"
     CDS             3550..3708
                     /locus_tag="KOU88_004026"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213835.1"
                     /translation="MLANRVRTGLRIPYDLNTKLILIAEERGMSKNSLILQILWDYIK
                     EIENKEVK"
     gene            3708..3935
                     /locus_tag="KOU88_004027"
     CDS             3708..3935
                     /locus_tag="KOU88_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213836.1"
                     /translation="MVELVKEFDLQTIKVGNAVKVNCKRFGFEIDCIVVVATEKELNL
                     AYFDEGRGCMEYQALITEDIQDGDYEIKILS"
BASE COUNT         1647 a          437 c          653 g         1244 t
ORIGIN      
        1 tcaagtctat aagttaagga atttttatac cattttttac gaacataagt tctgaaaagg
       61 gatataaaat ataatattat aaaaagaagg tgattggcta aatattttac atatttaagg
      121 ggcaaggaat aaatattata aattataaga gggtgacgca agtgggaaat tcagattgtt
      181 ctaaaatgtt ggcattttat gaaattatga aaatgttaga gactattgat gaagctaaat
      241 tttataattg taaagaagaa ataaagtcag agtttaagca tataaaaaaa gaggattgaa
      301 tcctcttttt ttatatattt ttatgtttat tctttatttt tagtattttg ctcctccaaa
      361 aaaagttttg ctatctttaa agctttattt ttagaatcat catcaagttc actaaaaata
      421 tcaagtattt ctttcatgtc atcagatgga tttagctttt taataagttc tttttctgtg
      481 atattagaaa tattaatttt gatattagtt ctacctaata aatagtcagt tgatatatct
      541 aaagtatcag ctatatgtct cacaacatca agcgctgggc ttcttttacc agtttcatat
      601 ccgttataag tgtttgctgg taaacttaat ttattagcca tctctttttg cattaatccg
      661 agttcttctc tctcttctct taatctttta gaaaatatat tgctttcatc tttatacatt
      721 gtaattgtcc ccctcttaaa aactataacg aatgtaatta ctcttattct actacaaaat
      781 acgcattttg tgattttaat tcgcaaaaag gaagaaaaaa aacaaaaaac gtattgacaa
      841 ttcacaaaac ggagtatatt atataaatat agaaacttca aattgagaat aaaaggagtg
      901 atatatattg aaaaattata tattgaaatc tcttagagta agacaaggat tgagacaaag
      961 agatttagca aaaatattag gaatgaatcc cagtacttat tcaagtaaag aaaatggcga
     1021 taggcgattc acagtaagtg aagcaataaa aatatcagat ttttttaata cagatttgag
     1081 agatattttt ttaaataaat aattcgcgaa atgtgaataa aaaggaggta gataaacatg
     1141 aataacttac aagtaataga aagaaacaac aaaagagttt taactacaca acaactagca
     1201 gatgtatatg aaacagatgc aagaaatata agcaacaatt ttaacaataa caaagataga
     1261 tttattgaag gtaaacatta tttttgtctg caaggtgatg atttaaggat atttaaacgc
     1321 ggttcatatg atataggaat tgcacctaat gtaaacaaac tttacctttg gactgaaaga
     1381 ggagcaaaca gacactgtaa aatattagat actgataaag cttgggaaca gtttgataac
     1441 ttagaagaaa catatttcaa agttaagcaa cagaagctaa cttgtataga agatgtatta
     1501 atagaaagtt taaaagaaat gaaagattta agacttcaag ttaaccaagc taacaatata
     1561 gcattagaag caaaaacaga ggttaaaaca ataaaagaag ttgtttcatt aaatgctact
     1621 gactggagaa aagatacgca acaattaatt gcaaggatag caaagaaaca aggtggattt
     1681 gaacatataa acatgcttag gagagaaagc tacgaattac taaataagcg atttggagtt
     1741 gacctacata gaagattaat caataaaaga agaaagatgg cagaagaagg tgtatctgaa
     1801 tctaaaagag agaaagttaa caatttagat gtaatacaag atgataagaa actcatagaa
     1861 gggtatgtgg ctattgtaaa agatatggct ttaaaatatg gaatatcaag tgatttaagc
     1921 aaaaattaag ttaaatcaca acagcacttt gaaaactaaa tacagaatat tttgaaaagg
     1981 agtggttaaa ttggaaaata aaaaaataga agaaataaaa aatgcattaa taggggtgaa
     2041 tcagatagag tggtctttag taaaatcttt tattgatatg tattttagta aaaaagccgc
     2101 caaacttgaa attgacgacc tagataattt tgatttgtat ataaaacgaa aattttaatt
     2161 actagcaatt tgtataaaga ttggatggat tctatagtca acacccttat agtaaatatg
     2221 aacataatct tgctgataca tagtatgttc ttcttcttta ttagaaggac tccatacatc
     2281 agcaccttct tcccaccata tgtaaggcga agaatggtta ctacccattt tacattctgg
     2341 gtcatcacat agattaaccc aattaccagc taaacaagca tatattttag tcataatatc
     2401 accaactttc atataaattt ggaatatatt ccatatttat attataccat gtagaacgaa
     2461 ggtgattaag tgttaatagg cgacaatata agtcaaatac taagaaaaag aaatataaaa
     2521 ccttataaat tagcaaaaga attaggaata gatgaaagtg gattatacaa aattataaga
     2581 aatgaaaaga aaaatccaac cataaacact ctaataaaaa tagctgatta tttagatgtt
     2641 acattagacg aattagttgg aagatagaaa ttaaatacag aatattttga aagtaggtgt
     2701 attgtatggc aaaagcagta gctaaagaac cattatttta tagagcaaaa gatgtagcta
     2761 aatttttaga tatatgcgaa gcaactgcat acaaaataat tgcagaatta aatgaagaat
     2821 tagaaaaaga aggttttaag actttttctg gcagggtatc agttgcttat tttaaagaaa
     2881 gatattgtta taagccaaga aagggggtga tttagttgaa tgtaagagta ttaatagctt
     2941 atatacagtt ttgtaatgat aagcaaataa aagcaagttt tgaaggtctt agaaaataca
     3001 acagagatat agagttagtt aacttgtatt taccagcaca tttaaaaata aagtaagcta
     3061 taaataatta aagaaaaagg tgattagatg caaagagagc agacaacaat acgcctgcct
     3121 aaagaactta aagaaaaatt agaaaagcag gcgagtaaaa aaggaagaag ttttaatagt
     3181 attttattaa gcatattaca agaatttatt cagaatccaa atgtatagga ccatgttctt
     3241 tttcaaacat ttctatatgt ttagtgacaa gaaattctat ttctttgtta gctgaacgag
     3301 cattatactc agctatatat ttaagtttat caagtttttc ttttggtatt ctaattgcaa
     3361 aatgaggatt tttatatgta cccattttag ccataatatc aactcctttg tgtagtctat
     3421 ttggcaacaa ttatatcaca aaaataaata caaaaaaata tataggcaac atatagacaa
     3481 cataataata aagtgttata ctttgtatta aagataggca acacatagat aacaatatag
     3541 gaggaaatta tgttggcaaa tagagtaaga actggattaa gaatcccata tgatttaaat
     3601 acaaaattaa tattaatagc agaagaaaga ggaatgtcaa aaaattcttt aatattacaa
     3661 atactttggg attacataaa agaaatagaa aataaggagg tcaaataatg gttgaattgg
     3721 taaaagaatt tgatttacaa acaattaaag taggaaatgc agtaaaagta aattgcaaaa
     3781 gatttggttt tgaaattgat tgtatagtag tagtagcaac agaaaaagaa ttaaatttag
     3841 catactttga tgaaggtaga ggctgtatgg agtatcaagc cttaataaca gaagatattc
     3901 aagatggtga ttatgagatt aaaattttat cttaggagga aataaaatgg taggtttatt
     3961 tgcaatatgt ttagcaggat t
//
LOCUS       DAFAZV010000120         3799 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFAZV010000120 DAFAZV010000000
VERSION     DAFAZV010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3799)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3799)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3799
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.123"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(304..921)
                     /locus_tag="KOU88_004028"
     CDS             complement(304..921)
                     /locus_tag="KOU88_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213837.1"
                     /translation="MVKYNVHKALAEKKLLEDKIDRCISNFKIVGTKKGSDKNVYETK
                     TSVEDFNVEVSSKYQQIEDLIYNYNALDKAINISNAITNVQIANKNYTVLEAIKRKNS
                     IELDKSLLRQMVSNYDCMMSEVNRRNEEVQRNTDKMFEEKEKSKDGAELISFYKKQQE
                     WSLVDPLKVREKIEKLRNEIEEFEKEVDFALSTSNALTIIDVDLK"
     gene            complement(977..1066)
                     /locus_tag="KOU88_004029"
     tRNA            complement(977..1066)
                     /locus_tag="KOU88_004029"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1031..1033),aa:Ser,seq:gct)
     gene            complement(1072..1148)
                     /locus_tag="KOU88_004030"
     tRNA            complement(1072..1148)
                     /locus_tag="KOU88_004030"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1112..1114),aa:Met,seq:cat)
     gene            complement(1363..1917)
                     /locus_tag="KOU88_004031"
     CDS             complement(1363..1917)
                     /locus_tag="KOU88_004031"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213838.1"
                     /translation="MNLQYFEKDKYYVYKHYIIDHDGKENVFYIGKGIGDRIYNQIRN
                     EKWYDIVKNNNYNYNVDIIKYFENEKDALDYEVKLQLYYWSNGQCKGCADIDAAIGKE
                     KIKKQNKLLEEGLVIQDDYLNKWLFKYELENIINTYELKDNKRRVMSANKFINYLKEC
                     NYRIEKIRKRTKKKQETLYKICNK"
     gene            complement(2010..2642)
                     /locus_tag="KOU88_004032"
     CDS             complement(2010..2642)
                     /locus_tag="KOU88_004032"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213839.1"
                     /translation="MSILSSNQIANIVGVDKNTISRYKNKLIKNNIFMPSNLSKTVTY
                     ATFKDIDVLSIKSELIPHKENCKNRVNQDKELDNFRYQVRLVADKNINFKRKENIIVD
                     NSLYEDYLNACRIIANTPFLKDKENYNRVVNMVKHNKHELNVTQKDKYIAFNEFAREI
                     GLVKLYQVHKTEYRTNVMKNKELLDIIVKAFRYRNNNSNINNKLVKYNSY"
     gene            complement(3125..3430)
                     /locus_tag="KOU88_004033"
     CDS             complement(3125..3430)
                     /locus_tag="KOU88_004033"
                     /inference="COORDINATES: protein motif:HMM:NF012442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBK3213840.1"
                     /translation="MRKNEYVKLFQEKLKEEGLELKQKEVDVVLDAFKELVVDIFKSG
                     EDATIGGFLKIGRKEIEACEKTHTLPGKEGEKYIIPASTKPTVKFINSFVKEHMILK"
     gene            complement(3542..>3799)
                     /locus_tag="KOU88_004034"
     CDS             complement(3542..>3799)
                     /locus_tag="KOU88_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213841.1"
                     /translation="WEKGVTQNEIAKQLGIAQKNVNLHIDRIVNKFIDKYTEIYEDEY
                     YYVYLVKGKYKKCSKCGEIKLIQRFDKNGKKGYRSNCKNCN"
BASE COUNT         1149 a          629 c          321 g         1700 t
ORIGIN      
        1 gccttgtagc taacaatagc taatataagt taacgcattt cgcatttatc aaggatttta
       61 tataactttt ttattttatt tttgatattt taataattta atcttttata cttgagattt
      121 cacatttgaa tttttaactt taagctttat atccattatt ctcttttata cagtacaatc
      181 gtttcgtttg tatgtaccca tcacttttat ataagcagtt tgatttttaa cccaaaatca
      241 atgggaactt ataatttatg ttattcgcct aacctgcaaa ttaaaaaata gtccaattaa
      301 ggactatttt aaatctacat ctataattgt aagtgcattt gatgtactca atgcaaaatc
      361 aacttccttt tcaaattctt ctatttcatt ccttaacttt tctattttct ctcttacttt
      421 taaagggtct actaaagacc attcctgttg ttttttataa aatgaaataa gttctgctcc
      481 atctttactt ttttcttttt cctcaaacat tttatctgta tttctttgta cttcttcatt
      541 tctacgattt acttcagaca tcatacaatc atagttacta accatttgtc tcaacaagga
      601 tttatctaat tctatactat tctttctttt tattgcttct aaaaccgtat aatttttatt
      661 agcaatttga acatttgtta tagcattaga gatattaatt gctttatcta atgcattata
      721 attatatatt aaatcttcta tttgctggta tttacttgaa acttctacat taaaatcttc
      781 tacacttgtt tttgtttcat atacattttt atcagaacct tttttagtac ctacaatttt
      841 aaaattacta atgcatctat ctatcttatc ttctaataac ttcttttctg ctaaagcttt
      901 atgaacatta tatttaacca taaaaacatc tcccttttaa ttaaaatatt attttaaaat
      961 aacaaactct ttttattgga agagaggaag ggatttgaac cctcgtatca attaattgac
     1021 ctaatagttt agcaaactat cctctttacc acttgagtac ctctccatat ttggtaggaa
     1081 taataggagt cgaacctatg acctttcggg tatgaaccga acgctctagc cacctgagct
     1141 atatcccttt tagtaatatc atcatctctg tattaacaga tatctattat taattactag
     1201 aactttaacc catatattac aatcatgaat aatatatccg aagctttagc tgaggataac
     1261 aactgaacga agtgaaggcg ttagttatag ctaccgcgtc acttacgttc cttgctatca
     1321 cttcggctaa cgccttgtga ttaaaattat aattataaaa tcctacttat tacatatttt
     1381 atataatgtt tcttgtttct tttttgttct ttttctaatt ttttcaattc tataattaca
     1441 ttcttttaaa taattaatga atttattagc agacattact cttcttttat tatcttttaa
     1501 ctcatatgta ttgatgatat tttccaattc atatttaaat aaccatttat ttaaatagtc
     1561 atcttgtata accagtcctt cttctaataa tttattttgt ttctttattt tttctttgcc
     1621 tattgctgca tctatatcag cacaaccttt acattgtcca ttgctccaat aatataattg
     1681 caattttacc tcataatcta atgcatcttt ttcattttca aaatacttaa taatatcaac
     1741 attataatta tagttattgt tttttactat atcataccat ttttcatttc tgatttgatt
     1801 ataaattctg tctccaattc cttttccaat ataaaagaca ttctctttac catcatgatc
     1861 tataatgtaa tgtttataaa cataatattt atccttttca aagtattgta aattcataac
     1921 atacaccttt aaaatatttc tttcaaaaaa atccgatgac ctgcatattg atatatatat
     1981 ttatataagt atgcgagtta tcggaaaaat taatatgagt tgtattttac tagtttatta
     2041 ttaatattac tattattatt tctataccta aaagctttaa caattatatc taataactct
     2101 ttatttttca taacattagt tctatattct gtcttatgta cttgatataa cttaactaat
     2161 cctatttctc ttgcaaattc attgaatgct atgtatttat ctttctgagt tacatttaat
     2221 tcatgtttat tatgtttcac catatttact actctattat aattttcttt atcttttaaa
     2281 aatggtgtat ttgctataat tctacatgca tttagataat cttcatacaa actattatca
     2341 actatgatat tttcttttct tttaaagttt atatttttat ctgctaccag tctaacctga
     2401 tatctaaaat tatctaattc tttatcttga tttactctat ttttacaatt ttctttatgt
     2461 ggtattaatt cacttttaat acttaagaca tctatatctt taaatgtagc atatgtaact
     2521 gttttagata gattagaggg cataaagata ttatttttaa ttaatttatt tttatatctt
     2581 gatatggtat ttttgtccac tcctactata tttgcaattt gatttgatga taatatactc
     2641 atattcccct ttatatcttg catagttaga atcacagcca tgtaatataa taatttattt
     2701 atatctactt tactatcaaa tttccagaca ttataagcaa tttgtttaaa aatatcatat
     2761 gctatatatt cactgtcttt tatttctttt ctataaaact ttcttttttt accttttcca
     2821 tcataaaaaa tattattttc ttctaattta gaagcatatt ttttaaaatc tttatataac
     2881 gtattttcac taacacatat tatcttgctt acttctttta tatttatttc ttctatgata
     2941 tcatcctctc tttcttaata aaaagaaaaa gaaagactta ctgctatctc acgacatgtg
     3001 ctttcttttt gcttaaaaga tggagattaa tggaatcgaa ccattaacaa tctcctatat
     3061 ctccacaatg ataagtccaa ttaagactta tccattttat atttatattt tatttagttg
     3121 ttaactattt taatatcata tgttctttta caaaagaatt tataaattta actgttggtt
     3181 tagtactggc tggtataata tatttttctc cttcttttcc tggtaaagta tgtgtttttt
     3241 cacatgcttc tatttctttt cttcctattt ttagaaatcc acctatagta gcgtcttcac
     3301 ctgatttaaa tatatctaca actaattctt taaatgcatc taatactaca tctacttctt
     3361 tttgttttag ttctaatcct tcttccttta gtttctcttg aaataatttt acatattcat
     3421 tttttctcat tttcaatctc tcctcgactt tatacatttt atttatttgt agtagtatta
     3481 attaccccta catatattaa tgtcttttcc agccgatttt ataccctatt ttccccaccc
     3541 attagttgca gtttttacag tttgaacgat agcccttttt cccattttta tcaaaccttt
     3601 gtattagttt aatttctcca catttgctac attttttata ctttcctttt actaaataaa
     3661 cataataata ttcgtcttca tatatttcag tatacttatc tataaactta tttactattc
     3721 tatcaatatg taaatttaca tttttttgag ctatacctaa ttgcttggct atttcatttt
     3781 gtgtaacacc tttttccca
//
LOCUS       DAFAZV010000121         3765 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFAZV010000121 DAFAZV010000000
VERSION     DAFAZV010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3765
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.124"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..664
                     /locus_tag="KOU88_004035"
     CDS             <1..664
                     /locus_tag="KOU88_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213842.1"
                     /translation="LKDKIIEYSKLHKVKRVHVMLLGDLISGHIHNSIRLENRENIVE
                     QIIEVSEILSEFIYELSKKINEIIVYSVGGNHDRVLPKKDENLDKDNFTLLIDEYIKL
                     RIKNLDNVIFQENIYDNDIIVAKICGNTCFAVHGDKDKMSTAIPKLTSLIKSIPDYIF
                     MAHLHNCKEDSYGESEIIVNGSFSGTDTYAKNLRLSSYTMQKLMIFNDDGRLCTYNIK
                     LK"
     gene            807..1667
                     /locus_tag="KOU88_004036"
     CDS             807..1667
                     /locus_tag="KOU88_004036"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213843.1"
                     /translation="MARKGKIKCSCCGEEKSAARDFYSSSSKLHKSLSTFPMCKNCVE
                     ELYDELVYKYAGDKKIAAKRLFVMLDVYYDEDLYNACINKENKGKSKWLGEYMKTKAN
                     ARYVSKSSLDNINSKNPVEDDIDSDFKLNEIKINNDMVERWGAGLRKEDYMFLENKFN
                     EFSMAYQCKRPAEKMLLEQISKCLLKSDEALRNGDATGFEKMNTLISKLMNDANIKPI
                     QEASLAENETITWGTWIDKIENYRPIGEPSEQFKDVDKIKTYINKWFIGQMRKVFDLA
                     SEDNPNDDQD"
     gene            1651..3426
                     /locus_tag="KOU88_004037"
     CDS             1651..3426
                     /locus_tag="KOU88_004037"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213844.1"
                     /translation="MMTKTRKLNNNEINSDKNKALEEGIIEWTKFYRENPHRFCIDYF
                     GLNLYLVQIILIYMFDECNYAMLICARGFAKSWIAAVYACCRAVLYPNSKIGIAALTK
                     SQAELIIREKIEKELVKQSPMLAREIKKIEYNNKFSKVTFHNGSTIEAIVSNEQSRGF
                     RFNILIVDEFRLVKKEIQDRILKPFLNVSRNLKFKKDGKYEDYPPEPNKELYLSSAWF
                     RMHEAYDKFKLYVKDMIDGRDKFVLNCNYKLSLHHGILDKERADEMKREMDAVSWIME
                     MESLFFGENEDAIFKSSYVNPCRTLKNPFYPPTDLEVLSSKNGKVKCNLQKRKGELRI
                     ISADIAVAEGDNNDNSVYTCWRLLPEKDYYERMVVHIESHNGMKPDKQAIRLKQLFFD
                     FEADFLVIDTQGVGQSVLSDLLRVNYDDARNKEYNAFSHANTNHLHNNFVSKENYPVI
                     FEIKAYGQINHDCIIGLLDVFLKNRIKLPINDVEANDMLSSTSGYAKKNYTDQARMIL
                     PYKQTTLLVNELINLETVKNDGQKWLKVKEKGKARKDRYSSLAYGNYLANLLDGELKK
                     RNSKNSGQIISFWSGGGNHNRTQRR"
     gene            3395..>3765
                     /locus_tag="KOU88_004038"
     CDS             3395..>3765
                     /locus_tag="KOU88_004038"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213845.1"
                     /translation="METIIELKGDKKDYTLDQIKYLNEQLRQRNYAMIENTINLSNEM
                     YKIRNISRDQVRKAMTAPYKNVELLQKVSLLLKETSGTYKRILNMISTMNTFDHYIIP
                     INISKFKDKNDYVDSFFKSAAL"
BASE COUNT         1561 a          390 c          646 g         1168 t
ORIGIN      
        1 tttaaaagat aaaattattg aatatagtaa gttacataag gttaagagag tacatgtaat
       61 gttacttgga gatttgattt ctggacatat acataattct ataagattag aaaatagaga
      121 aaatatagtt gaacaaatta tagaggtgtc tgaaatactt agtgaattta tatatgagtt
      181 gtctaaaaaa attaatgaga ttattgttta ttcagtagga gggaatcatg atagagttct
      241 tccaaagaaa gatgaaaact tagataaaga taattttaca ctattgatag atgaatatat
      301 aaagctaaga attaaaaatt tagacaatgt aatatttcaa gagaatatat atgataatga
      361 cataatagtt gctaaaatat gtggaaatac atgttttgca gtacatggag ataaagataa
      421 aatgtctaca gcaattccta aattaacatc tcttataaaa tcaattcctg attatatttt
      481 catggctcat ctacacaatt gtaaagaaga tagttatgga gaaagtgaaa ttattgtaaa
      541 tggaagtttt tctggaacag atacatatgc taagaatcta agattaagtt catatacaat
      601 gcaaaaatta atgatattta atgatgatgg aagattatgt acttataata ttaagcttaa
      661 atagagctaa ttattaaagg actaatacaa taatattcca tcattatgat atggtattag
      721 tcctttaatg ggctaaattc aatctccctt ctgaggtcgg tttcatactg acctctcttt
      781 tttcatctca aaaggagagt gataagttgg ctagaaaagg taaaatcaaa tgttcttgtt
      841 gtggagaaga aaagtcagca gcaagagatt tttatagtag ctctagtaaa ttacataaga
      901 gcttgagtac ttttcctatg tgcaaaaatt gtgttgaaga attgtatgat gaattagttt
      961 acaagtatgc tggggataaa aaaatagcag caaagagact atttgtaatg ttagatgttt
     1021 attatgatga agacttatat aatgcatgta ttaacaagga aaacaaagga aaatctaaat
     1081 ggttaggcga gtacatgaaa actaaagcaa atgctagata tgtgagtaaa tcaagtcttg
     1141 ataatattaa ttcaaaaaat ccagttgaag atgatattga ttctgatttt aaattaaatg
     1201 aaataaaaat aaataatgat atggttgaaa gatggggagc aggactaaga aaagaagact
     1261 atatgttttt agaaaataaa tttaatgagt tttctatggc atatcaatgt aaaagacctg
     1321 ctgaaaagat gttattagaa caaatctcta aatgtttact aaagagtgat gaagctctaa
     1381 gaaatggtga tgctacaggg tttgaaaaaa tgaatacctt aatatcaaag cttatgaatg
     1441 atgcaaatat aaaacctatt caagaagcaa gtttagcaga aaatgaaact attacatggg
     1501 gtacatggat tgataaaata gaaaattaca gacctatagg agagccttca gaacaattta
     1561 aagatgtaga taaaataaaa acatatatta ataagtggtt tataggacaa atgagaaaag
     1621 tatttgattt agctagtgag gataatccaa atgatgacca agactagaaa gctaaataat
     1681 aacgaaatta actcagataa aaataaagct cttgaagaag gaataattga atggactaag
     1741 ttctatagag aaaatccaca tagattttgt attgattatt ttggtcttaa tttatattta
     1801 gttcaaatta ttcttatata tatgtttgat gaatgtaatt atgcgatgct tatatgtgcc
     1861 agagggtttg caaagagctg gattgctgct gtatatgcat gttgtagagc tgttttatat
     1921 ccaaattcta aaattggtat agctgcactt actaaatcac aagcagaact tattataaga
     1981 gaaaagatag aaaaagaatt agtaaaacaa tctcctatgt tagctagaga gataaaaaaa
     2041 atagaatata ataacaaatt ttctaaagta acatttcata atggaagcac tatagaagct
     2101 atagtatcaa atgagcaatc aagaggtttc cgtttcaata ttcttattgt agatgagttt
     2161 agattggtaa aaaaagaaat acaagataga attcttaaac catttttaaa tgtaagtaga
     2221 aatctaaagt ttaaaaaaga tggaaaatat gaagattacc ctccagagcc taataaagaa
     2281 ttatatttaa gtagtgcatg gtttaggatg catgaagcat atgacaaatt taaattgtat
     2341 gtaaaagata tgatagatgg tagagataaa tttgtactta attgtaatta taaactttct
     2401 cttcatcatg gaatattaga taaagagaga gcagatgaaa tgaaaagaga aatggatgcc
     2461 gtttcttgga ttatggagat ggaatcactt ttctttggag aaaatgaaga tgctatattt
     2521 aaatcatctt atgtgaatcc atgtagaaca ttaaaaaatc cattttatcc tccaacagat
     2581 ttagaagtat tatcatctaa aaatggaaaa gttaagtgta atttacagaa aagaaaaggt
     2641 gaactaagaa taatttctgc tgacattgct gttgcagaag gtgacaataa tgataactca
     2701 gtgtatacat gttggagatt attgcctgaa aaagattatt atgaaagaat ggttgttcat
     2761 atagaatctc ataatggtat gaagccagac aaacaagcaa taagattaaa acaattattc
     2821 tttgattttg aagcagattt cttagttata gatactcaag gggtaggcca aagtgtttta
     2881 tctgatttac ttagggttaa ttatgatgat gctagaaata aagaatataa tgcattttct
     2941 catgctaata caaatcattt acacaataat tttgtttcaa aagagaatta tccagttata
     3001 tttgagatta aggcatatgg acaaataaat catgattgta taattggctt acttgatgta
     3061 tttctaaaaa atagaataaa gttacctata aatgatgtag aagctaatga catgttaagt
     3121 agtacatctg gatatgcaaa gaaaaattat acagaccaag cgagaatgat attaccatac
     3181 aaacaaacta cattacttgt aaacgaatta ataaacttag aaactgttaa aaatgatggt
     3241 caaaagtggc ttaaggtcaa agaaaaggga aaagcaagga aagatagata ttcttcctta
     3301 gcatatggaa attatctagc aaatttacta gatggagaat taaaaaagag aaatagtaag
     3361 aacagtggac aaataatttc attctggtca ggaggtggaa accataatag aactcaaagg
     3421 agataaaaaa gattatactt tagaccaaat aaagtactta aatgaacaat taagacaaag
     3481 aaattatgca atgatagaaa atactataaa tctatcaaat gaaatgtata agataagaaa
     3541 tataagtaga gaccaagtaa gaaaagctat gacagcccct tacaaaaatg tagaattact
     3601 acaaaaggta agtcttttac ttaaagaaac atctggtaca tataaaagaa ttctaaatat
     3661 gatttcaacc atgaatacat ttgaccatta tattatacca ataaatattt ctaaatttaa
     3721 agataaaaat gattatgtcg actctttttt taaatcagct gcact
//
LOCUS       DAFAZV010000122         3585 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFAZV010000122 DAFAZV010000000
VERSION     DAFAZV010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3585
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.125"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..325
                     /locus_tag="KOU88_004039"
     CDS             <1..325
                     /locus_tag="KOU88_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBK3213846.1"
                     /translation="GDTLKLQEYIDGVYTGRSLQREVSYILNDSNYIKNGYIILGLIN
                     NTNHYMFKVVRDYKKENYLICRQGKVFIGYILGNFACCKESLEQFTIPLEYIEKISRV
                     EFKPL"
     gene            518..1072
                     /locus_tag="KOU88_004040"
     CDS             518..1072
                     /locus_tag="KOU88_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015393853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HBK3213847.1"
                     /translation="MSKKDKLSVFISLILRHKPEIIGIKLDDYGYADVNELIEKINNT
                     GRNINIEILEQIVKEDNKQRYSFNDDRSKIRANQGHSINVNVELRELEPPRFLYHGTA
                     TRFLDNIKKEGIVSKSRLYVHLSNDIDTAVQVGKRHGVPVVLKINTGKMYENGYKFYL
                     SENNIWLCKYIPFEYVEKISRVVK"
     gene            1099..1425
                     /locus_tag="KOU88_004041"
     CDS             1099..1425
                     /locus_tag="KOU88_004041"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213848.1"
                     /translation="MDFNFRKICEKDELTDDFIIKICQLSHEEFGGTIYVPCNIHPCG
                     WDELEVPNPKDLDSDKLMEEFLLEYKFECENISSNIYDSDHPFIGKTLREILMIVDCR
                     FIIGVI"
     gene            1440..2216
                     /locus_tag="KOU88_004042"
     CDS             1440..2216
                     /locus_tag="KOU88_004042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213849.1"
                     /translation="MENIELTPRDYFEDIKNKKQKNTNENLDIVYENSLILLNKYIIT
                     GQKKGAKKLMFLLECIEKERSVIELGIDTFVYKEDIEKYIDDISKNTVKIIELENYER
                     EIPDEIVEIIEKTKDIFDKMYVLFTDYTGKITKKISKERRDKDPILFGVFSDEKSRAI
                     VDRFYYLGDWEDEYCDLTLEKMINDYKKKGKQDISKHIITPKSLDELKKELDSLEKNN
                     DTYKQIINIKPLPTPSNSSVEPPKSNIFKKIKNRVFKNEK"
     gene            2206..2610
                     /locus_tag="KOU88_004043"
     CDS             2206..2610
                     /locus_tag="KOU88_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213850.1"
                     /translation="MKNNVDLTENRDFRDVRGKGLSILGIEETPNRMLNGFSDFGIRH
                     LYGKNLEFEFDKNEIFLTGNANDREEKKFFMLCEENKVCIRCGDELKEGWDKVSIELC
                     NKCYEMLDVEYKNKKIIRELFFRDRDVNIELI"
     gene            2648..3037
                     /locus_tag="KOU88_004044"
     CDS             2648..3037
                     /locus_tag="KOU88_004044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213851.1"
                     /translation="MKDVWLYSWDDECFRSDEYESKEEAVEAAKEELKRLGEIKRWAY
                     IGKKEEVDIPDIDAEDALEFVQDRIDNEFGGYGEDWFENIRAEDIVILENRISKVFKK
                     WIDEFGYKPYWFVVRDTEEIELKNAVN"
     gene            3097..3417
                     /locus_tag="KOU88_004045"
     CDS             3097..3417
                     /locus_tag="KOU88_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213852.1"
                     /translation="MFIKGFRCIFRHKFSRIKDCYLITTKSQQHTCKIWVCKYCGQIV
                     AGSTPVYHPNMKVNEYCVKCELLACSNNYEGYCNSKDKEIEFKSICLEDNKEILQCKN
                     FDLE"
     gene            3448..>3585
                     /locus_tag="KOU88_004046"
     CDS             3448..>3585
                     /locus_tag="KOU88_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213853.1"
                     /translation="MKINVHVKTNKIGSDCELELEIDDDDLKDMSDEEREDYIDKIAW
                     DY"
BASE COUNT         1511 a          259 c          707 g         1108 t
ORIGIN      
        1 aggagacact ttaaaattac aggaatatat agatggtgtt tatacaggaa ggagtttaca
       61 aagagaagta tcttatatac ttaatgattc aaattatatt aaaaatgggt acataatttt
      121 agggttaata aataacacaa atcattatat gtttaaagtt gtaagagatt ataaaaaaga
      181 aaattattta atatgtagac aagggaaagt attcataggg tatattcttg ggaactttgc
      241 ttgttgcaag gagtctttag aacaatttac tataccatta gaatatatag agaaaataag
      301 tagagtagaa tttaaaccat tgtaattaaa atcaagattt taatagaaaa ggagttatta
      361 aaaatgaaga aaaatccaat aagaattaaa aaatgtgact gtggtggaga tgtatatgaa
      421 cttaatacac aattaggtac tatgtatcaa tgtaaaagct gtggcgagat gtatagatag
      481 tgctaaaaca ttagttaagg aatatggggt gaagtaaatg agtaaaaaag ataagctatc
      541 tgtttttatc agtttaatat taagacataa accagaaatt attggaatta aactagatga
      601 ctatggatat gcagatgtta atgaattgat tgaaaaaata aataatactg gtagaaatat
      661 taatatagaa atccttgagc aaatagttaa agaagataat aagcaaaggt acagttttaa
      721 tgatgataga agcaagatta gagcaaatca aggacattca attaatgtta atgtggaatt
      781 gagggaatta gaaccaccaa ggtttctcta tcatgggaca gcgactagat ttttagataa
      841 tattaaaaag gaaggtattg ttagcaaaag tagattatat gtacatttat ctaacgacat
      901 agatactgct gttcaggttg ggaaaaggca tggtgtacct gtagttttaa aaattaatac
      961 aggaaaaatg tatgaaaatg gttataaatt ttatttatct gaaaacaata tttggttatg
     1021 taagtatata ccatttgaat atgtagagaa aataagtaga gtagttaaat aaaattatag
     1081 aaaataggag gttattgaat ggatttcaat tttagaaaga tttgtgaaaa agatgaactt
     1141 actgatgatt ttattataaa aatttgccag ttgtcacatg aggagtttgg aggcactatt
     1201 tatgtaccat gtaatattca tccatgtggg tgggatgagt tggaagttcc gaatccaaag
     1261 gatttagatt cagataaatt aatggaagaa tttctattag aatataaatt tgaatgtgaa
     1321 aatatttcaa gcaatattta tgatagtgac catccattta taggcaaaac attgagagag
     1381 attcttatga tagtggattg tagattcata attggtgtta tataaggagg atattaaata
     1441 tggaaaatat agaattaaca cctagagatt attttgagga tataaaaaat aaaaagcaaa
     1501 aaaacacaaa tgaaaatctt gatatagtat atgaaaattc tttaattctt ttaaacaaat
     1561 atattataac tggtcaaaaa aagggtgcta agaaattaat gtttttactt gaatgtattg
     1621 aaaaagaaag aagtgtaata gagctgggaa tagatacatt tgtgtataaa gaagatatag
     1681 aaaaatatat tgatgatata tctaaaaata cagtaaaaat aatagaactt gaaaattatg
     1741 aaagagaaat accagatgaa atagtagaaa taatagaaaa aacaaaagat atatttgata
     1801 aaatgtatgt tttatttact gattatacag gtaaaattac aaagaagata agcaaagaga
     1861 ggagagataa agacccaata ttatttggag ttttttcaga tgagaaaagc agagctattg
     1921 tagatagatt ttattatctt ggagattggg aagatgagta ttgtgattta acattagaaa
     1981 aaatgataaa tgattataag aaaaaaggaa aacaagacat atcaaagcat ataattacac
     2041 ctaaatcatt agatgaatta aaaaaagaat tagattcttt agaaaaaaat aatgatacat
     2101 acaagcagat tatcaatata aagccattgc ctacgccaag taactctagt gtagaaccac
     2161 ctaaatcaaa tatatttaaa aaaataaaaa atagagtatt taaaaatgaa aaataatgtt
     2221 gatttaacag aaaataggga ttttagagat gtaagaggaa aaggtcttag tattttaggt
     2281 attgaagaga caccaaatag aatgttgaat ggttttagtg attttggaat tagacatctt
     2341 tatggtaaaa atttagaatt tgaatttgat aaaaatgaaa tatttttaac tgggaatgcg
     2401 aatgacagag aagaaaaaaa gttctttatg ctttgtgaag aaaataaggt ttgtatcaga
     2461 tgtggagatg aattaaaaga gggatgggat aaagtgagca tagaattgtg taataaatgc
     2521 tatgaaatgt tggatgttga gtataaaaat aaaaagataa ttagagaatt attttttaga
     2581 gatagagatg taaatataga gttaatttaa gagatatata agaaaaataa ttagaggagg
     2641 aatttatatg aaagatgttt ggttatatag ttgggatgat gaatgtttta gaagtgatga
     2701 atacgaaagt aaagaagaag ctgttgaggc agctaaggaa gaacttaaga ggctcggaga
     2761 gattaaaaga tgggcttata ttggaaaaaa agaagaagtt gatattcccg acatagatgc
     2821 agaggatgct ttagagtttg ttcaagatag aattgataat gaatttggag ggtatggaga
     2881 agattggttt gaaaatatac gtgctgaaga tatcgttata ctagagaata gaataagcaa
     2941 agtattcaaa aagtggatag atgaatttgg atataaacca tattggtttg ttgttagaga
     3001 tacggaagaa atagaactaa aaaatgctgt caattaaaac tagtattttc agtgatgaca
     3061 acagtatgac aagaataatg agtatataaa ggagtgatgt ttattaaagg ttttagatgt
     3121 atattcagac ataaattttc aaggataaaa gattgttatt tgattacaac aaaaagtcag
     3181 cagcatactt gtaagatttg ggtgtgtaaa tattgtggac aaattgtagc tggttcaact
     3241 cctgtttatc atcctaatat gaaagtcaat gagtattgtg taaagtgtga gcttttagca
     3301 tgttcaaata attatgaggg atattgtaac tctaaagata aagaaattga atttaagtct
     3361 atttgcttag aagataataa agagattttg cagtgtaaaa attttgattt ggaataaaat
     3421 ttagcttaag taggagaatt ttagaatatg aaaataaatg tacatgttaa aactaataaa
     3481 attggttcag actgtgagct ggagcttgaa atagatgatg acgatttaaa agatatgtct
     3541 gatgaagaga gagaggatta tatagataaa atagcatggg attat
//
LOCUS       DAFAZV010000123         3311 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFAZV010000123 DAFAZV010000000
VERSION     DAFAZV010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3311
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.127"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..576
                     /locus_tag="KOU88_004047"
     CDS             <1..576
                     /locus_tag="KOU88_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213854.1"
                     /translation="HRGMKQQELADKIGINMQSLSKIERGVNFPTFDTLEKIMDVLGV
                     MPNELLSGEWKYVNQSEKEVCQFLRIEERLNAELKHGHYDNFFDSEEEWLEYELEKLR
                     EYITDYINGKSIVASDLYPIKEFIQHLKFQKLLDRYDDLYSMDMFGESIEGHKYRTPY
                     QVVKMINPNSKEDMELLREVLKNNHFDDEDE"
     gene            complement(851..1408)
                     /locus_tag="KOU88_004048"
     CDS             complement(851..1408)
                     /locus_tag="KOU88_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005946872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3213855.1"
                     /translation="MKTTKEAVIKATSDLADEKGLNNVSLKAVAQKLNIRTPSLYNHI
                     ESLDNLLLEVAHNGMRDMNERMMKIAVGKIGKEAIKLVSIEYLNYMIEHPGVYETIQW
                     AVWHGTEETATIFNNYLSLLTTLIQSCSLNKDKTLEILNMLTGIIHGYTTLQLGNAFS
                     ASDKVRFELAEAIDTLLVGIFQKYK"
     gene            1586..2281
                     /locus_tag="KOU88_004049"
     CDS             1586..2281
                     /locus_tag="KOU88_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3213856.1"
                     /translation="MCTRFVYNGIDKIVGFNFDIDLSVWDHTVITEENRFYIGIKMPD
                     GMYHSFHGINKNGNVGTLLYVHGNENARYIESEDCITISELTEKFIKAEISFDKALDI
                     VKKKKIIYAPDATMQAMLSDKKGRVLIIEPGIGYRYEQENFSLITNYSILKPDITKPY
                     IVSGDTRYEVAKELLAGYDKDFSVNDAFKVLKSVSQKDLWATRVSFVYSTEKNKVYYV
                     LNNDFSNVFEFQF"
     gene            2580..2999
                     /locus_tag="KOU88_004050"
     CDS             2580..2999
                     /locus_tag="KOU88_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008728841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3213857.1"
                     /translation="MNPSSFEHIVRIQFNALMMTVIKCTVKNRNRQFARRSKREVLFC
                     ELSDTKNVECVTKDNYSCDYISFEVLNFTIQISNEKLAVALYKLSNKERDVILLRYFQ
                     SMSDQEIAELYHVSRSAIYRRRSNGLKKLKTVLKERN"
     gene            3004..3243
                     /locus_tag="KOU88_004051"
     CDS             3004..3243
                     /locus_tag="KOU88_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213858.1"
                     /translation="MKKEYGYPTLKVICQASAGNETAIREILKFYDAYICKLCLRPFY
                     HSESGKIIMQVDEELKGQIHTEMMKAILKFEIRVK"
BASE COUNT         1179 a          447 c          603 g         1082 t
ORIGIN      
        1 cacagaggaa tgaaacaaca ggaacttgcg gataaaatcg gtatcaatat gcagagcctt
       61 tccaagattg aacgaggtgt gaattttcct acctttgata cattagaaaa gataatggac
      121 gtgctgggtg taatgcccaa tgaattatta tcgggagaat ggaagtatgt taatcaatcc
      181 gaaaaggaag tctgccagtt tttaagaatt gaagaacgat taaatgcaga actaaaacat
      241 ggacattatg acaacttctt tgacagcgag gaagaatggc tggaatatga gttggaaaag
      301 ttacgggaat atattaccga ctacatcaac gggaaaagta ttgtagcgtc cgacctttat
      361 ccaatcaaag aatttatcca gcatttgaag tttcaaaaac tgttagaccg ctatgatgat
      421 ttatacagca tggatatgtt cggggaaagc atagagggac ataaatatag gacaccttat
      481 caagtcgtaa aaatgataaa ccccaattca aaagaagata tggaattatt acgggaagta
      541 ttgaaaaata accattttga tgatgaggac gaataacttt tttcctcttt gtagaagata
      601 cagcaaacaa aaagcccagt aaagagtgca aagcaccacc aatggtggca aggctcttga
      661 cagggctttt tcttttctgt ggagggtaat caagaggaag aaaagataaa atttgatttg
      721 tggtaaatcg gataatatca atgaaattgt cacggtacaa gtttgggcta tataaggaat
      781 agtaactgga agattgttgg ataaaagaaa aaggcttgca gttctgtatt gatttgcaag
      841 cctaaatata ttatttatac ttctggaaaa tcccgactaa taaagtatct atcgcttcag
      901 ctaattcaaa tctaacttta tctgaggcag aaaaagcgtt tcctaattgc aaagttgtat
      961 aaccgtgaat tattccagta agcatattta atatttcaag tgttttgtct ttgttaagac
     1021 tgcacgattg gataagagta gttaataatg aaagatagtt gttaaaaatg gttgctgttt
     1081 cctctgttcc gtgccacaca gcccattgaa ttgtttcata aactccgggg tgttcaatca
     1141 tatagtttag gtattcgata gaaactaact taattgcttc tttccctatt tttccaacgg
     1201 caattttcat cattctttca ttcatgtcac gcataccatt atgagcaact tctaaaagaa
     1261 gattatctaa actttctatg tgattatata aagatggtgt acgaatgttt aatttttgag
     1321 caacagcttt taacgaaacg ttatttaatc ctttttcatc tgctaagtct gatgttgctt
     1381 ttattactgc ttctttagtg gttttcatag ttatgcacct cattcaaaat atcatacaaa
     1441 cacaattcta gctaattgaa ttagtgtagt caataacaca attagaaaat tatgattatt
     1501 tattgacttt cctacaaaaa cattttaaaa tactaattga attagttaaa taactatttg
     1561 aagtagtatt ttgaggagtg attatatgtg tacaagattt gtttacaatg gtatagataa
     1621 aattgttggt tttaattttg atattgacct ttctgtatgg gatcatactg taattaccga
     1681 agaaaataga ttttatattg gtattaaaat gcctgacggt atgtatcatt catttcatgg
     1741 gataaataaa aatggtaatg taggaacact tctttatgtt catggtaatg aaaatgcaag
     1801 gtatatagaa agcgaggatt gtattacaat atctgaatta acagaaaaat tcattaaggc
     1861 agagatttct tttgataaag ccttggacat tgttaaaaag aaaaaaatta tttatgcacc
     1921 agatgctact atgcaagcta tgctttctga taaaaaagga cgagttttaa ttattgaacc
     1981 cggaattggg tatagatatg aacaagaaaa tttttcactt attacaaatt attctattct
     2041 aaaaccagat ataacaaagc cgtacattgt ttctggggat acaagatacg aagtggctaa
     2101 agagttattg gcaggatatg ataaagattt ttcagtaaat gacgcattta aagtattaaa
     2161 atctgtttct caaaaagact tgtgggcaac tagggtttca tttgtatatt ctacagaaaa
     2221 aaataaagtt tattatgtct tgaacaatga ttttagtaat gtatttgaat ttcagtttta
     2281 atactaatga atttataaat ttgcaattat gataagaaag gttattatga taggactaaa
     2341 aaagcaagat ataaaagcat tgaaagtaac tgctgtggaa agttttagga ataatcttat
     2401 acgattatgc actacctaac agcattttat caacaactaa atattttaca atattaaaag
     2461 ttcgtacaga cggtatattt tgtacggact tttttcttgt tcttcttttt gtattttcca
     2521 aagatataga cggtatctcc gtttatatat ttcagcgtat gcggaaagga ggtgagatta
     2581 tgaacccatc ttctttcgag catatcgtta gaatacagtt taatgctttg atgatgactg
     2641 ttattaaatg cacagtaaaa aacagaaaca gacagtttgc aagacgttct aagcgtgaag
     2701 ttttattctg tgaattatca gatacgaaaa atgttgaatg tgtaactaag gataactatt
     2761 cttgtgatta catttcgttt gaagtcttga attttacaat tcaaatatca aatgagaaac
     2821 ttgctgttgc tttatataag ttatcgaata aagagcgtga tgtaattcta ttacgctatt
     2881 ttcaaagtat gagcgaccaa gaaatagccg aattatatca tgtatcacgt tctgctattt
     2941 atcgcagaag aagtaacgga ttgaagaaac taaaaacagt attgaaagaa aggaattgaa
     3001 ccaatgaaaa aagaatatgg ctaccctaca ttaaaagtaa tatgtcaagc gtctgctgga
     3061 aatgaaactg ccataagaga gattttgaag ttttatgacg cttatatatg taaattatgc
     3121 ttgcgtccgt tttaccactc tgaaagtggt aaaatcatta tgcaggttga tgaagaatta
     3181 aaaggtcaaa tccatacaga aatgatgaaa gcaatcttga aatttgaaat cagagtaaaa
     3241 taatcatact acatgaatga aaaacgggag atacacagat atttgtgcta tctcccatgt
     3301 tgtttttgtg t
//
LOCUS       DAFAZV010000124         3286 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFAZV010000124 DAFAZV010000000
VERSION     DAFAZV010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3286)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3286)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3286
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.128"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            135..2063
                     /locus_tag="KOU88_004052"
     CDS             135..2063
                     /locus_tag="KOU88_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HBK3213859.1"
                     /translation="MILDNSPADSWIRITGVIVTYNNTLYQVVDTETNKKYIYWDADN
                     PGTLKVSNVRLPEGNTQFLVVVNDNGKHTEVPINSSIFDISFDGNSRKNTEEQIWGLY
                     ETDKKHNEKFVVIEKDIDGIHQTVLEVQEDASHIKENMSLIDQRAENVNILVKEVTKN
                     FGQSQENITLRENINKAIIKLNADLGTFSSNMSNYFNDNEITDEEKEKIDIELNLLDT
                     DKASLYAELQKLIDKTTGVDLVAINTSKTALDTASTNLNSIINSVISDSIITPSDRIL
                     AINANAQYNLKINELKNTVDRIYITGMGGSISEEFSQINATAKEIKLEVARVDGVTKT
                     NAAEIKLTKDDITMIVTRNGSGSIVGIKPDKIEFGFNDISNYVEISRSGLTVNQGAIA
                     CDILTTPSGHEPIIRLFGSSRSGFAIDARRSDGSSQASAIRLKYDSNNYFWVGYDTAE
                     IYVDGEEHFIVERDDTFVRCGGATFTFTNGDSLGIGYSFYPERSSTDLGCDDYKWRYL
                     YSRSTLSESDKKFKENIVYIKDIKNRTRSSITPTPFLDFIKDEFKPATFDYIVSAEKD
                     RTIADSQIGFIANDFKDSYVGKTFLYDYGEENGLMFSPSGYTTVVATALQEEIQKREE
                     LEMIVSELNEKINNLGGY"
     gene            2065..2220
                     /locus_tag="KOU88_004053"
     CDS             2065..2220
                     /locus_tag="KOU88_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213860.1"
                     /translation="MEVNLQKAYTVAFEEIKSLYNELILYKALNMQQQEEIENLKKEL
                     EEQNKEQ"
     gene            2232..>3286
                     /locus_tag="KOU88_004054"
     CDS             2232..>3286
                     /locus_tag="KOU88_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3213861.1"
                     /translation="MKNYEIKNHTIEVDFSNYRINKRLLDYFIYNENDVKTAYIEAIL
                     KNKDEIIDLSEYDRVLVSITKSDGQKVNGECEVVDAENGVVEIELSRQALASVGINTF
                     QLSLVKEGTLLNTTNLYYRVEEGMINDDDITSTDEYGVLLVIIAQAEEIIKNNKELTK
                     RVEQLEITILGNEEVRDKAEQIRIYNEDIRNIQEEEREFNELTRQNQEANREESIQNM
                     QIQVDDKLTDCQLQLDEMIDAKSEEIDNIVDDKMLDVQAQTDKKFQDLDTRANNIFDL
                     YDKTFEDKLTDNQEQIDYKLDEVNQAISNVEDCIDESTTKLDTKIKEIDDKIVEVNTA
                     KTDMTTTVSNKITEFEN"
BASE COUNT         1408 a          350 c          578 g          950 t
ORIGIN      
        1 tttaactaaa gctgaacatg caacgagaac attaaactct aaaagacatt tattcattca
       61 gcaacagaag aaaagaatta acctaccaga tgaatatatt cctaagaaaa atatacaaaa
      121 ggagctgatg taaattgata ttagataatt caccagcaga ttcatggatt agaattactg
      181 gagtaattgt tacctacaat aatacacttt atcaagtagt agatacagag acaaataaaa
      241 aatatatata ctgggatgct gataatccag gaacattaaa agtttctaat gtaagattac
      301 cagagggaaa cacacaattt ttagtagttg taaatgacaa tggaaaacac acagaagttc
      361 ctataaattc ttctattttt gatatttcat ttgatggtaa ttcaagaaaa aatacagaag
      421 aacagatttg gggattatat gagactgata aaaagcataa tgaaaagttt gtagttattg
      481 aaaaagatat agatggaata catcaaacag ttttagaagt acaagaagat gcatctcata
      541 taaaagaaaa tatgtctctt atagaccaaa gagctgaaaa tgtaaatata ttagtaaaag
      601 aagttactaa aaattttggt cagtcacaag aaaatataac cttaagagaa aatataaata
      661 aagctataat taagttaaat gcagatttag gtacatttag ttctaatatg tctaattatt
      721 ttaatgataa tgagattaca gatgaagaaa aagaaaagat tgatattgaa cttaatttat
      781 tagatacaga taaagcgagt ttatatgcag agttacaaaa acttattgat aaaactactg
      841 gagtagactt agttgcaata aacacttcaa aaacagcatt ggatacagca agtaccaatc
      901 taaactctat aatcaattca gttatttcag atagtataat tacaccttca gacagaattt
      961 tagctataaa tgcaaatgct caatataact taaagataaa tgaacttaaa aatacagtgg
     1021 atagaattta tataacaggt atgggtggaa gtatatcaga agaattttct caaataaatg
     1081 ctacagctaa agagataaaa ttagaagtgg ctagagtaga tggtgtgact aaaactaatg
     1141 ctgctgaaat taaattaacc aaagacgata taacaatgat agttacaaga aatggaagtg
     1201 gttcaattgt aggaattaaa cctgataaaa ttgaatttgg atttaatgat atatcaaatt
     1261 atgtagagat aagcaggagt ggtctaacag taaatcaagg agctatagca tgtgatatat
     1321 taactactcc atctggccat gaaccaataa tcagattatt tggaagtagc aggtctggat
     1381 ttgcaataga tgcaagaagg tctgatggtt ctagtcaagc atcagctata agattaaaat
     1441 atgatagcaa taattatttt tgggtaggat atgatactgc tgagatttat gttgatggag
     1501 aagaacactt tattgttgaa agagatgata cttttgtaag atgtggagga gctacattta
     1561 catttacaaa tggagatagt ttaggtatag gatattcatt ttatccagag cgttcatcaa
     1621 ctgatttagg ttgtgatgat tataaatgga ggtatttata ttcacgttct actctaagtg
     1681 aatctgacaa aaagtttaaa gagaatatag tatacataaa agatattaag aatagaactc
     1741 gttcaagtat aacgccaaca ccatttttag attttataaa agatgaattt aaaccagcaa
     1801 catttgatta tattgtatca gcagaaaaag atagaacaat tgcagatagt caaatagggt
     1861 ttatagctaa tgattttaaa gatagttatg ttggaaaaac atttctatat gattatggag
     1921 aagaaaatgg attaatgttt agcccatctg gttatacaac tgttgtagca actgcacttc
     1981 aagaggaaat acaaaaaaga gaagaattgg aaatgatagt tagtgaatta aatgagaaaa
     2041 ttaataattt aggaggatat taatatggaa gtaaatttac aaaaagcata tacagtagca
     2101 tttgaagaga taaaaagttt atataatgaa ctaatacttt ataaagcact taacatgcaa
     2161 caacaagaag aaattgagaa cttgaaaaaa gaactagaag aacaaaataa agaacaatag
     2221 gatgtgatac tttgaaaaat tatgaaataa agaatcatac catagaagta gattttagta
     2281 attatagaat aaataaaagg ttactagact attttattta taatgaaaat gatgttaaaa
     2341 cagcttatat tgaagcaata ttgaaaaata aagatgaaat aatagattta tctgaatatg
     2401 atagagtttt agttagcatt acaaaaagtg atggacaaaa ggttaatggt gaatgtgaag
     2461 ttgtagatgc agaaaatggt gttgtagaga tagaacttag tcgacaagca cttgcaagtg
     2521 ttggtataaa tacatttcaa ctatcccttg tgaaagaggg aactctactt aatactacaa
     2581 atctttatta tagagttgaa gagggtatga ttaatgatga tgatatcacc tcaactgatg
     2641 aatatggagt attattggta ataatagccc aagcagaaga gattataaaa aacaataaag
     2701 agttaactaa aagagttgaa caacttgaaa taactatctt aggaaatgaa gaagttaggg
     2761 ataaagcaga gcagattagg atttataatg aagatataag aaacatacaa gaagaagaaa
     2821 gagagtttaa tgagttaaca cgtcaaaacc aagaagcaaa tcgtgaagaa tccattcaga
     2881 atatgcaaat ccaagttgat gataaactta ctgattgtca actccaatta gatgaaatga
     2941 tagatgccaa gtctgaagaa atagacaata ttgttgatga taaaatgctt gatgtccaag
     3001 ctcaaacaga taagaaattt caggacttag atactagagc taataatatt tttgatttat
     3061 atgataagac atttgaagat aaacttacag acaaccaaga acaaattgat tataaacttg
     3121 atgaagtaaa tcaagctata tctaatgtag aagattgtat tgatgaaagt actacaaaat
     3181 tagatacaaa gataaaagaa atagatgaca aaatagttga agtaaatact gctaagacag
     3241 atatgacaac aactgtatct aacaaaataa ctgaatttga aaatag
//
LOCUS       DAFAZV010000125         3071 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFAZV010000125 DAFAZV010000000
VERSION     DAFAZV010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3071)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3071)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3071
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.129"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..748)
                     /locus_tag="KOU88_004055"
     CDS             complement(<1..748)
                     /locus_tag="KOU88_004055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3213862.1"
                     /translation="MKICITVGHSILKSGACTSADGVVNEYQYNKSLAPVLADTFRKE
                     GHKVDVIICPEKQFKTKNEEKSYKIPRVNSGGYDLLIELHLNASNGQGKGSEVLYYSN
                     KGLEYATRICDKLGTVFKNRGAKLDKRLYILNSSKPTAVLIESFFCDNKEDYDKAKKL
                     GHEGIAKLIVEGVLNKNINNEGVKQMYKHTIVYDGEVDKIPATVVGWGYNDGKILICD
                     IKDYVPGQTQNLYVVGGGACEKISSITKEKF"
     gene            complement(748..1005)
                     /locus_tag="KOU88_004056"
     CDS             complement(748..1005)
                     /locus_tag="KOU88_004056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK3213863.1"
                     /translation="MDNLISFIPEQLLILVAALSIIGKGCKKYKQLDNKYIPIVLLVL
                     GIGFSIWMLGLSPVAVLQGVICWGISIGINQTYKQLKEENK"
     gene            complement(1021..1251)
                     /locus_tag="KOU88_004057"
     CDS             complement(1021..1251)
                     /locus_tag="KOU88_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin XhlA family protein"
                     /protein_id="HBK3213864.1"
                     /translation="MNEELMKEKISTLETRVKEHGKQIDRIEIEQAKFAIQIQNLCSD
                     IKNLTGVLKWLVGVIITTLIGFFIFAIQRGIF"
     gene            complement(1293..1475)
                     /locus_tag="KOU88_004058"
     CDS             complement(1293..1475)
                     /locus_tag="KOU88_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015981517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213865.1"
                     /translation="MNINNVVVRILAERILSRGLNPLKNREFELDDVTNTEYRKAVED
                     YIIEHSGVVEGAEPIK"
     gene            complement(1475..1768)
                     /locus_tag="KOU88_004059"
     CDS             complement(1475..1768)
                     /locus_tag="KOU88_004059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213866.1"
                     /translation="MNRANRIIYDQTGKILLQTGEATGDILEHDTITELHYIDVEYGN
                     IDYSKQYIESINPITKEPILKDIPIYLSEEEKRIQELENQILLNENEKVGGLL"
     gene            complement(1782..>3071)
                     /locus_tag="KOU88_004060"
     CDS             complement(1782..>3071)
                     /locus_tag="KOU88_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213867.1"
                     /translation="AGGGLEGGTGYSSNDRYRPGGTQYQGGIGRVNTENGSFGKGCSV
                     KDSTGEGGGGGWFGGAGMNGVGAGGGGSSYVLTKDSYKPTGYTPTSEYYFDNIVMTPG
                     GNTAGAYGYAQITLLQSLPFLNISSYNSTQATFKADHTDPTLLTKIEYFIDDVLKETI
                     TTDLTTEKTINYTLEDNALHTLKIVVTDSNNATAEKVLSISKNIMPLPENVNLNDIST
                     KLVEVNAGFKVGKTSIINTLALKNIEASLNNTLVELSEKIKTSFDSSDASVQDLMSQL
                     TQANNTISQLNSKYKYATGTAYARENSSLIACVYDPNTSHTVTETSPYWLDLNGIGFI
                     PDIFFAECEYEPHSNAFYKYFVFAIKNTFPISNNTGFVVNIAFNKEYGDESFKLRGAL
                     YTLGKRHVSMDNNGVRVPSLSTLNDFRAYKWHAIKFK"
BASE COUNT          907 a          596 c          358 g         1210 t
ORIGIN      
        1 taaatttttc tttagtaata gaacttatct tttcacatgc gccacctcct acaacataaa
       61 gattttgcgt ctgacctggt acgtaatctt ttatatcaca tatcagtatt ttcccatcat
      121 tataacccca accaactaca gttgcaggga ttttgtcaac ttctccatca taaacaattg
      181 tatgtttgta catctgttta actccctcat tatttatatt tttatttaat acaccttcta
      241 caattaactt agcaatacct tcatgaccta gtttcttagc tttatcataa tcttctttat
      301 tatcacagaa gaaactttca attaatactg ctgtaggctt tgaactattt aagatatata
      361 atcttttatc taatttagca cctctatttt taaatactgt acctagttta tcacatattc
      421 tagttgcata ctctaagcct ttattactat aatataggac ttctgaacct ttaccttgac
      481 cgttacttgc atttaaatgt aactctataa gtaaatcata tcctccacta ttaactctag
      541 gtattttata agacttttct tcattcttag ttttaaactg cttttctggg catattatta
      601 catctacctt atgcccttct tttctaaatg tatctgctaa tactggtgca agagatttgt
      661 tgtattgata ctcgttaact actccatcag cagaagtaca tgctccactt tttaaaatac
      721 tgtgtcctac tgttatacat attttcatta tttattttcc tccttcaact gtttgtaagt
      781 ttggtttata cctattgata taccccaaca aatcacgcct tgtaagactg caacaggact
      841 tagtcctagc atccaaatag aaaatccgat tcccaacaca agtaatacaa ttggaatgta
      901 tttattgtct aattgtttat attttttaca acctttacct ataatagaga gagcagctac
      961 taaaattagc aactgctctg gtataaaact tattaaatta tccatttttt atcctcctaa
     1021 ttaaaatatt cctctctgaa ttgcaaatat aaagaatcct atcaatgttg taattataac
     1081 tcctacaagc cacttaagta ctccggttaa attctttata tcactacata ggttttgtat
     1141 ttgtatagca aactttgctt gttcaatctc tattctatca atttgtttac catgctcttt
     1201 tactcttgtt tcaagtgtac ttattttttc cttcataagt tcttcattca tgaaaacctc
     1261 ctattgcttt gtattaaaaa aaggaacatt acctatttta ttggttctgc tccttctact
     1321 actccactat gctctataat ataatcctct actgcttttc tatactctgt gttagttaca
     1381 tcatctaatt caaattctcg attttttaaa ggatttaagc ctctacttaa aatcctctct
     1441 gctaatattc ttactacaac attatttata ttcattataa tagccctcct actttttcat
     1501 tttcatttag taatatttga ttttctaact cttgtattct cttttcttct tcgcttaaat
     1561 agattggaat atcttttaaa ataggttctt ttgttattgg atttatagat tctatatact
     1621 gtttactata gtctatattt ccatattcaa catcaatata atgtaattct gttattgtat
     1681 catgctctaa tatatctcct gttgcttctc ctgtttggag taatatttta ccagtttggt
     1741 cgtaaattat tctatttgct ctattcattt tatcacctca tttatttaaa ttttatcgca
     1801 tgccatttat atgctctaaa atcatttaga gtgcttagtg aaggtactct aactccatta
     1861 ttatccatgg aaacatgtct tttgccaagg gtatataaag ctcctcgtaa tttaaaagat
     1921 tcatcaccat attccttgtt aaaagcaata ttaactacaa acccagtatt attagaaatg
     1981 ggaaaagtat ttttaattgc aaaaacaaaa tacttataaa aagcattcga atgtggttca
     2041 tattcacatt cagcaaaaaa tatatcagga ataaatccaa ttccatttaa atcaagccaa
     2101 taagggctcg tttctgtaac agtatgagaa gtattagggt catatacaca tgcaattaag
     2161 gatgaatttt ctctagcata agcagttcct gttgcatatt tatacttaga atttaactgt
     2221 gatatagtat tattagcttg tgttaactgg ctcatcaaat cctgcacact agcgtctgaa
     2281 ctatcaaaac ttgtttttat tttctctgac aactcaacaa gtgtattatt taaacttgct
     2341 tctatattct ttaatgctaa agtatttata atacttgttt tcccaacttt aaatcctgca
     2401 ttaacctcaa ctaattttgt tgatatatca tttaaattta cattttcggg cagtggcatt
     2461 atattcttac ttatacttaa cactttttct gctgtagcat tattactgtc tgtaacgact
     2521 attttaagtg tgtgtagagc gttatcttct agtgtatagt taattgtttt ctctgttgtt
     2581 aaatctgttg ttatagtttc ttttagcaca tcatctataa aatattctat cttagttaat
     2641 aatgtagggt ctgtgtggtc agctttaaat gttgcttgtg tagaattata agatgatata
     2701 tttaaaaatg gtaatgattg aagtaaagtt atttgtgcgt aaccataagc accagcagta
     2761 tttccacccg gtgtcataac aatattatca aaataatatt cagatgttgg tgtgtagcca
     2821 gtaggcttat aactgtcttt agtcaataca taactacttc cacctccacc tgctcctaca
     2881 ccattcatgc ctgcaccacc aaaccagcca cctccgccgc cttcgccagt tgaatcttta
     2941 acagaacacc cttttccaaa acttccgttt tctgtattta cacgaccaat accaccttga
     3001 tattgagtac caccgggacg gtatctgtca ttagaactat acccagtacc tccttctaat
     3061 cctcctcctg c
//
LOCUS       DAFAZV010000126         3017 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFAZV010000126 DAFAZV010000000
VERSION     DAFAZV010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 3017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3017
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.130"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            49..426
                     /locus_tag="KOU88_004061"
     CDS             49..426
                     /locus_tag="KOU88_004061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213868.1"
                     /translation="MYLRKLSKSELIVMKFIWNLDTKVKSYQIINYMKEKYSWSEKTT
                     LKTLSKLSNKRFIYVQETSQCTYYTISIKEDKYHEFISQKIHKLLGCNSIKSLLASLF
                     QEELTDEKITSLEEWVKNWEEEE"
     gene            complement(567..1829)
                     /locus_tag="KOU88_004062"
     CDS             complement(567..1829)
                     /locus_tag="KOU88_004062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding repeat-containing protein"
                     /protein_id="HBK3213869.1"
                     /translation="MKFKRKALTLAIISSIVMSSTLLVSAKELKFRPPAHRIQGANKY
                     ETAGLIADRRKYTQAIIINTDKSLADGLSASGLAGASNSPILLTKQNSIPNSTLKRLD
                     KFKKIYLIGGVNSISKNVENILKNKKIKVIRIEGKDRIDTSYNVAKEISNLKKVDEVY
                     FTNAYQGEADSISISPVAAKYKNPVVLTNGKNIPFKTDGVKTYAIGGTASINDSLVNS
                     TKATRIGGVDRLDTNEKIIKHFYKDELKHPNQICIVSSDNLIDALLSSTIHKEYPVFL
                     VNETNDKSLVTSANFPIIIGDIKNEILDQCLTPDYMLTGNTKRSDISKALDAIYKAKG
                     SKAHEYCYTYNYGNSRYKKAENIDFPHYEFEIISVKNVKQDESSTDGSDTYTDKEDSI
                     KTVGTLIVNSETLEVYEYSFDTQKLTKI"
     gene            complement(1984..2304)
                     /locus_tag="KOU88_004063"
     CDS             complement(1984..2304)
                     /locus_tag="KOU88_004063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213870.1"
                     /translation="MQKIPQAELKVMKFIWNKNDIVTSKEVMEAMESEYNWKATTTLT
                     LLSRLTIKRFLDSERIKRITHYTILITKEEYKIFETKRFLEEVHSNSIESLISSLEDC
                     YKNK"
     gene            complement(2442..2792)
                     /locus_tag="KOU88_004064"
     CDS             complement(2442..2792)
                     /locus_tag="KOU88_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009899255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213871.1"
                     /translation="MLEDEIYNVIGKRIRNYRRKAGYNQNTLAKKAGLFPAYIGQIER
                     GESKASLRSIFKIANALEIPLEVLFENIIQNENDVETLSSEAYELIDSLTVKEQKAII
                     RLIKEIIEYRKFEE"
BASE COUNT         1028 a          411 c          338 g         1240 t
ORIGIN      
        1 attgctgtaa tatttaaatt aaataaacaa atgatgggag agataattat gtatttaaga
       61 aaattatcaa agtcagaatt aattgtaatg aaatttatat ggaatttaga tacaaaagta
      121 aaatcatatc aaatcattaa ttatatgaaa gaaaaatata gttggtcaga aaaaacaaca
      181 ttaaaaactt tatctaagtt atcaaataaa aggttcatat atgttcaaga aacaagtcaa
      241 tgtacatact atacaatttc aattaaagaa gataagtatc atgaatttat atcacaaaaa
      301 atacataagc tcttagggtg caattctata aaaagccttt tagcatcatt gtttcaagaa
      361 gaattaacag atgaaaaaat aacttcattg gaagaatggg taaaaaactg ggaagaagag
      421 gaataaagat aatatatact attccttaaa aatctattta aagaataatt gaaattttga
      481 ttttaatata atttctttaa tcaactctaa catacaaaaa taagactctt ttcaatatta
      541 actaaagagc cttattttat aattgattat attttagtta acttttgtgt atcaaaacta
      601 tactcatata cttctaatgt ttcagaattt acaattagag ttcctactgt tttaatgcta
      661 tcttctttat cagtataagt atcagaacca tcagtgctag attcatcttg tttaacattt
      721 ttaacactga ttatttcaaa ctcatagtgt ggaaaatcta tattttcagc ttttttatat
      781 cttgagttac cataattata tgtataacaa tattcatgtg cttttgaacc ttttgcttta
      841 tatatagcat ctaaagcttt tgagatgtca cttcttttag tattaccagt taacatataa
      901 tctggagtta agcattggtc taaaatttca ttttttatat cacctattat tattgggaaa
      961 ttagcactag taactaatga tttgtcatta gtttcattta ctaaaaatac aggatattct
     1021 ttgtgtattg tagaagataa tagtgcatct attaaattat cagaacttac aatacatatt
     1081 tgatttggat gttttaattc atctttataa aaatgcttaa ttattttttc attagtgtca
     1141 agtctatcaa caccaccaat tctagttgct tttgtactgt tcactaaaga gtcgtttatt
     1201 gatgctgttc ctccaatagc atatgttttt accccatctg ttttaaatgg tatattcttt
     1261 ccatttgtta atacaactgg atttttatat ttagcagcaa ctggagatat acttatagaa
     1321 tcagcttctc cttgataagc atttgtaaaa tatacttcat caaccttttt tagattgctt
     1381 atttcttttg caacattata acttgtgtct attctgtctt ttccttctat cctaataacc
     1441 tttatttttt tgttttttag tatattttct acatttttgc ttatagaatt aactccacct
     1501 attaaataga tttttttaaa tttatctaat cttttaagag tagaatttgg tatagaattt
     1561 tgtttagtaa gtaatattgg cgagttagaa gctccagcta aaccactagc actcaaccca
     1621 tctgcaagac ttttatctgt gtttataatt attgcttggg tgtattttct tctgtctgct
     1681 attaaacctg ctgtttcata cttatttgct ccttgtattc tatgagctgg aggtctaaat
     1741 tttagttctt tagctgaaac taataatgtg ctagacatga caatagaaga tattatagct
     1801 aaggttaatg cttttctttt gaatttcata ttgtaaaatc ctcccatcct tttatactat
     1861 gaatgatagt gtatattatt ttagttgtca actctctatg tatattttct tatatatata
     1921 agaataaatt gtattaatta tatcgttacg aaaacttttt gtatataata aaagttcact
     1981 tctttattta ttcttataac aatcctctaa agaactaatt aagctttcta tagaattaga
     2041 atgtacttct tctaaaaatc tctttgtttc aaatatttta tattcttctt ttgtaataag
     2101 tattgtataa tgtgtaattc tttttatcct ctcagaatct aaaaaacgtt taatagtgag
     2161 tcttgaaaga agagttagtg tagttgtcgc cttccagtta tattctgatt ccatagcttc
     2221 cataacttct tttgatgtta ctatatcatt cttattccat atgaatttca taacttttaa
     2281 ttcagcttgt ggtatttttt gcatggatat gtacattcct ttctgcaatt aaaatatcaa
     2341 catatataga cgttaaaata ataaaatata tgttataagt atatattaac ataaagtaaa
     2401 agaagatgtc tcaatcttaa gacatcttct ttattaaatt tttattcttc aaattttcga
     2461 tactcaatta tttcttttat caatctaatt atcgcttttt gttcttttac tgttaaacta
     2521 tcaattaact cataggcttc agacgaaaga gtttcaacat cattttcatt ctgtataata
     2581 ttttcaaata aaacttctaa aggtatctct aatgcatttg caattttaaa aattgaacga
     2641 agtgatgctt tactttcacc tctttcaatt tgaccaatat aagcaggaaa caaaccagcc
     2701 ttctttgcta atgtattttg attataccct gcttttcttc tataatttct tattctttta
     2761 ccaattacat tatatatttc atcttctaac atttttatca ttccttatta gattatatta
     2821 gtttatttat cttaatgata tgttatacat gtcaaaaata tacttatata acatgtaata
     2881 ttattaaata tatattatat aagtatgtat atatttaata agaagctatt gtagacaaaa
     2941 aaaataaagc cctttaaaga aaactcattt aagagtaatc cttaaagggc ttattattta
     3001 tctatctctt tttctta
//
LOCUS       DAFAZV010000127         2995 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFAZV010000127 DAFAZV010000000
VERSION     DAFAZV010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2995)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2995)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2995
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.131"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..314)
                     /locus_tag="KOU88_004065"
     CDS             complement(<1..314)
                     /locus_tag="KOU88_004065"
                     /inference="COORDINATES: protein motif:HMM:NF024886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase N-terminal SAM-like
                     domain-containing protein"
                     /protein_id="HBK3213872.1"
                     /translation="MATFEKRSKRIKIEGNINKNNEKLIKGFLQAKKIAGLSEKTIYV
                     YKCDLYTWAKYLHDEMEDLLIEDCTEDDIMEYISFRMEDNHVNRIKVIFSGISSLYDH
                     LR"
     gene            complement(349..660)
                     /locus_tag="KOU88_004066"
     CDS             complement(349..660)
                     /locus_tag="KOU88_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213873.1"
                     /translation="MLSKEMVELLSQYGYTAILLMVLMLWLGKYLEKNRQLEQDDRKK
                     ERAYFSREIKEQRTLFGNTIDKFDDKLDKFAEALNTNNSRLERVETDITKIKDKLETR
                     D"
     gene            complement(661..912)
                     /locus_tag="KOU88_004067"
     CDS             complement(661..912)
                     /locus_tag="KOU88_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK3213874.1"
                     /translation="MDIMQFIPENLIMLIGGLYILGTFIKESNIKNKYIPFILLVIAM
                     ISSCLFMKELSIEAVFEGILCWGASIGINQIQVQNRKEK"
     gene            complement(924..1541)
                     /locus_tag="KOU88_004068"
     CDS             complement(924..1541)
                     /locus_tag="KOU88_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBK3213875.1"
                     /translation="MNILDKSTATLEQVFSYLDTLKNNSNPPHFLCGAIVPIIYKEAE
                     KKGVNPVIAIAQAFVETGYFNFGRVLNPSYCNMCGLKGNKGGGDLDPTAHTRFNCWED
                     GVSAFIDHLALYAGAKGYPKYSELVGKVEYKVNGTTLDPRHFPYLHGEAKTVESLSGK
                     WCPDMNYGKSIINICNKISSMKVENNDVKLEQIKTKVKELNEILG"
     gene            complement(1553..2368)
                     /locus_tag="KOU88_004069"
     CDS             complement(1553..2368)
                     /locus_tag="KOU88_004069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK3213876.1"
                     /translation="MNIKTLTIHAGHNPDNKIGSGAIGNIKESTEARNVLKELLPLAQ
                     KECKVYDCTCNNGTSQSDILNKIIAKCNSYNTDLNVSIHFNSGGGRGVEVLVYNLNDK
                     ETVEIASRICKKITETYHAKGDKDFKNRGVKEKKTLAFLRRTKAKSILVECCFVDTSD
                     TKKYNAKDMAIDIYEGIFNKSVAGKPQDNKVKYAIVYEGEVDKVIAQLMAMNYKTNEV
                     SVCDLENYVPGHCENLYVIGGASSKIKTSERFTKLQGDDRWATLHKVLDFIGK"
     gene            complement(2447..2617)
                     /locus_tag="KOU88_004070"
     CDS             complement(2447..2617)
                     /locus_tag="KOU88_004070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213877.1"
                     /translation="MYNILKRMIEQKNYETREELQTKLDVFYAMNRIKESEYTELTNL
                     LNKEDTLVEPII"
     gene            complement(2643..2969)
                     /locus_tag="KOU88_004071"
     CDS             complement(2643..2969)
                     /locus_tag="KOU88_004071"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213878.1"
                     /translation="MDIEKKIEILIEYGFENDLNNIDNYFIADGKKIFTPVIKNGELI
                     KTGEQVYNEWLELQNNPPKSEPSIEEINADKITILIENQKQQDSLLVDNAYRIAMLEL
                     NTNNVL"
BASE COUNT          892 a          548 c          297 g         1258 t
ORIGIN      
        1 cttctaagat ggtcatatag agatgaaatg cctgaaaata ttacttttat tctattaaca
       61 tgattgtcct ccatcctaaa tgaaatatat tccattatat cgtcttcagt acaatcttcg
      121 attaataaat cctccatttc atcatgcaga tatttagccc aagtatataa gtcacattta
      181 tatacatata tagttttttc acttaaacca gctattttct tagcttgaag aaatccttta
      241 attaactttt cattattttt atttatgttg ccttctatct taattctttt acttcttttt
      301 tcaaatgttg ccaaatactt cacttcctta taaaaaagac tagagaaatt aatctctagt
      361 ctctaattta tctttaattt ttgttatgtc tgtttcaact ctttcaagtc tgctgttatt
      421 agtatttaat gcttcagcaa atttatctaa tttatcatca aacttatcta ttgtattacc
      481 aaataaagtt ctctgctctt taatttctct tgaaaaataa gctctttctt tttttctatc
      541 atcttgttct agttgtctat tcttttctaa atattttcca agccataaca tcaataccat
      601 taaaagtatg gctgtatacc catactgact taataattca accatttctt tagataacat
      661 ctacttttcc tttctgttct gtacttgtat ttgatttatc cctatagatg ctccccaaca
      721 caaaatacct tcaaagacag cttctattga cagctctttc ataaacaaac aactgcttat
      781 cattgctata actaacaaga taaaaggtat gtatttattt ttaatattag attcttttat
      841 aaatgttcct aatatgtaaa gcccacctat taacattatt aaattttcag gtataaattg
      901 cattatatcc atgtgatttc ctcctatcca agaatctcat ttaattcttt tactttagtt
      961 tttatttgct ctaattttac atcattgttt tctaccttca ttgaacttat cttattacat
     1021 atatttatta tgcttttgcc ataattcata tctggacacc atttgcctga taaactttct
     1081 actgttttag cttctccatg taaatatgga aaatgtctag ggtctaatgt agttccattt
     1141 actttatatt caactttacc aactaattca ctatattttg gatatccctt agctccagca
     1201 tataatgcta gatggtcaat aaatgctgat actccatcct cccaacaatt aaatcttgta
     1261 tgagctgttg ggtctaaatc tcctccacct ttatttcctt taagaccaca catattgcaa
     1321 taagaaggat ttaaaactct accaaaatta aaatatccag tttctacaaa tgcttgagca
     1381 attgcaataa ctggatttac accttttttc tctgcttctt tatatataat tggtactata
     1441 gctccgcata aaaaatgtgg tggattagag ttatttttta atgtatctaa atacgaaaag
     1501 acttgttcta gtgtagctgt tgatttatct aatatattca attcattacc tcctacttgc
     1561 ctataaaatc taacacttta tgaagtgtag cccatctatc atcaccttgt aacttagtga
     1621 atctctcgct agttttaatt ttactggatg ctccaccaat tacatatagg ttttcacaat
     1681 gtccaggaac ataattttcc aaatcacata cagagacttc attagtctta taattcatgg
     1741 ccattaattg ggctataact ttatctacct caccctcata aactattgca tatttcactt
     1801 tgttatcttg tggtttacca gctacagact tattaaatat tccttcgtaa atgtctatgg
     1861 ccatatcttt agcattatat tttttagtgt cagatgtgtc tacaaagcag cactcgacta
     1921 aaattgactt tgccttcgtt cttcttaaaa atgctagagt tttcttttct ttaactccac
     1981 gatttttaaa atctttatca ccttttgcat gataagtttc agttattttt ttacatattc
     2041 ttgatgctat ttcaacagtt tctttgtcat ttaaattata aactaaaact tctactcctc
     2101 gaccaccacc actgttgaaa tggatactta catttagatc agtattatat gaattacatt
     2161 tagctataat tttattcaat atatcacttt gagaagttcc attgttacaa gtacagtcat
     2221 aaactttaca ttccttttga gctaaaggta ataactcttt tagtacattt cttgcttctg
     2281 tagattcctt tatatttcct attgctccag aacctatctt attatctgga ttatgtcctg
     2341 catgaattgt taatgttttt atattcaaaa ttaccactcc ttttaattaa aagagaattg
     2401 aaattaatca atcctctaaa attgacataa aaaaaacctt tatactttag ataataggtt
     2461 ctactagtgt atcttcttta tttaataaat ttgttaactc tgtgtattca ctttccttta
     2521 tcctgttcat agcgtaaaat acatctaact tagtctgcaa ttcttctcta gtttcataat
     2581 tcttttgttc aatcattctt tttaaaatat tatacatgtt gtttcctcca ttttttatag
     2641 ttttataaca cgttatttgt gttaagttct aacatagcaa ttctataagc attatctact
     2701 aataaactgt cttgttgctt ttgattttct attaaaattg taattttatc cgcatttatt
     2761 tcttctatac ttggctctga tttaggtgga ttattttgta attctaacca ctcattataa
     2821 acctgttctc ctgttttaat tagctctccg ttttttatca ctggagtaaa tattttttta
     2881 ccatctgcaa taaagtaatt atctatatta tttaaatcat tctcaaatcc atattctatt
     2941 aaaatttcta ttttcttttc tatatccatc ttatttttcc tttctaaatt aaata
//
LOCUS       DAFAZV010000128         2966 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFAZV010000128 DAFAZV010000000
VERSION     DAFAZV010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2966)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2966)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2966
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.132"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..730
                     /locus_tag="KOU88_004072"
     CDS             <1..730
                     /locus_tag="KOU88_004072"
                     /inference="COORDINATES: protein motif:HMM:NF021378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBK3213879.1"
                     /translation="GEKGKQKIADGFLCKECFKKYAVATFTPGNNLYGLPTKLKVERA
                     IESKDTKEEELKNFNPTKKILKLIEFDDDNKKFIVLNGFNREKVSLNVYNYSDVIEYE
                     LLENGETVTKGGIGRALAGGVLFGGVGAVVGGVTAKRKTKAFIDSLKIKITLNNLSNP
                     SVYVNLIQLRTKSNSSIYKMAYSSAQEILSILSIIVKDNEDGNLQDKPDDAIQQVKGL
                     KELLDLGAITEEEFNTKKKELLNL"
     gene            797..>2966
                     /locus_tag="KOU88_004073"
     CDS             797..>2966
                     /locus_tag="KOU88_004073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBK3213880.1"
                     /translation="MATIQTSIRIFDGMTPAFRNMTNAINTTINSFDRLQQRLHNPIN
                     AGGIQTSQQSLNNIENILTRIEQNIGKADEQQRRFNEDINKGISNTDRLLGSVKKLAG
                     AYIGVKTVGGLGSLSDQMTSTNARLAMINDGQLSDGGLNKMIFQSAERSRASYLDTAQ
                     IVSRIGMNAGSAFSSTREIVSFAEQLNKKFIIAGASTQEMSSALLQLTQGLGSGVLRG
                     EELNAVFESAPNIIKSIADYLDVDIGKIRGMASEGMLTADIVKNSLLAASAETNKQFE
                     QMPYTLGQIFTSVKNNAVMIFGAIQKKIEDTVSSGGFRTFIVNVTDSLYVLGAVGYSV
                     FNGFIDLLSSPVFQNFFNVMIVGTSLITQGLGWIITQALSVANVFAQNWSIIAPIIYG
                     VTIAIGIYTIAAIALAVANKVASLSAGWFNFQMTQTVIMHELATGATWMQVAAQYGLN
                     AALYACPLTWIVLGFIAVIAVIFMVIAAINHFAGTSLTVLGVIVGAVFAAVAAIQNVM
                     IGLLNRCITVNEAIANGWNQCVYFMKQAIAKGVIFIIEKMASLNDSVNSAGNALGKAF
                     VDGANIAIRGVNKLVDLLNKIPGVNIGKVGEATFTPVKADNSYIQQQINSLNKWVGNA
                     PEKVVLERMGYKDIGAAFEKGSALGTKWQNSITDKFKDTFDINKMIENAKKKLGLDDL
                     WDDKYGLGDGFGSGGLNSPLSDAAKGTKDTAGNTAKMAKTM"
BASE COUNT         1110 a          366 c          637 g          853 t
ORIGIN      
        1 tggagaaaaa gggaaacaaa aaatagctga tgggtttttg tgtaaagagt gttttaagaa
       61 atatgcagtt gccaccttta ccccaggaaa taatttatat ggattgccaa ctaaactaaa
      121 agtcgagaga gctattgaat caaaggatac taaagaagaa gaacttaaaa attttaatcc
      181 tacaaaaaaa atattaaaac ttatagaatt tgatgatgat aataagaaat ttattgtttt
      241 aaatggattt aatagagaaa aagtgagttt aaatgtttat aattacagtg atgttataga
      301 atatgaactt ttggaaaatg gtgaaactgt gactaaaggt gggataggaa gagctttagc
      361 aggaggagtt ttatttggag gagtaggtgc tgttgttggt ggagtaacag ctaaaagaaa
      421 aacaaaagct tttatagata gtcttaagat aaaaataacc ttaaataatt taagtaatcc
      481 tagtgtttat gtaaatttga tacaattaag aactaagagt aattcttcga tttataaaat
      541 ggcatattct tctgcacaag aaatattatc tattttatca ataattgtaa aagataatga
      601 agatgggaat ctacaagata agccagatga tgcaatacaa caggtaaagg gattaaaaga
      661 attattagac ttaggagcaa taacagaaga agaatttaat actaagaaaa aagaattatt
      721 aaatttgtaa tattacaaag cacttactta ggtaggtgtt tttttatgta agaattttag
      781 aaaggagagt gaaaatatgg ctacaataca aacatctatt agaatttttg atggaatgac
      841 acccgctttt cgtaatatga ctaatgctat caacactacg attaacagtt ttgataggct
      901 gcaacaaagg ttgcataatc ctattaacgc aggtggaata caaacatctc agcagagctt
      961 aaataatatt gaaaacatct taactagaat agaacagaat ataggaaaag cagatgaaca
     1021 acagagaaga tttaacgaag atattaataa agggataagc aatacagata gattgcttgg
     1081 aagtgttaag aaactagcag gagcttatat cggagtaaag acagttggag gcttaggtag
     1141 tttaagcgac caaatgacca gtacaaatgc gaggttggcg atgataaatg atggtcaact
     1201 ctcagatgga gggttaaata agatgatttt ccagtcggct gagaggtcaa gagcatctta
     1261 cctagacaca gcacaaatag tatcgcgaat tggtatgaat gcaggaagtg cattttctag
     1321 tactagagaa atagtaagct ttgcagagca actcaacaaa aagttcataa ttgcaggagc
     1381 tagtacacaa gaaatgagtt cagcattatt acagctgact caaggtttag gaagtggtgt
     1441 gttgagaggt gaggaattaa atgctgtgtt tgaatcagca cctaacatca tcaaaagtat
     1501 tgcggattat ctcgatgtcg acataggaaa aattcgaggt atggcaagtg aaggaatgtt
     1561 gactgcggat attgtgaaaa attccttgct tgctgcatca gctgaaacaa ataagcaatt
     1621 tgaacagatg ccttatacac ttggtcaaat tttcactagt gtaaagaata atgcagtaat
     1681 gatttttgga gctatacaaa aaaagattga ggatacagta tcaagtggag gattccgaac
     1741 ctttattgta aatgtaactg attctttgta tgtcttggga gctgttggat atagcgtttt
     1801 taatggattt attgatttat tgagcagtcc agtttttcag aattttttta atgtgatgat
     1861 tgttggaact agtttaatta cgcaaggatt ggggtggata ataacacaag cactaagtgt
     1921 tgctaatgta tttgcacaga attggtcaat tattgctcca attatatatg gagttacaat
     1981 agcgattggt atatatacaa tagcagctat agcacttgct gtagcaaata aagtagcatc
     2041 tttatcagct ggttggttta attttcaaat gactcaaaca gtaattatgc acgagttagc
     2101 tacaggagct acatggatgc aagtagcagc acaatatggt ttaaatgcag cattgtatgc
     2161 ttgtccgctt acatggatag tgcttggatt tatagcagta atagctgtga tttttatggt
     2221 aatagcagcg ataaatcatt ttgcagggac ttctttgact gtactagggg taatagtagg
     2281 tgcagtattt gcagcagtag cagcaataca aaacgtaatg attggacttc taaatagatg
     2341 tataactgta aatgaagcaa ttgctaatgg ctggaatcag tgtgtgtatt ttatgaaaca
     2401 agctattgca aaaggtgtaa tctttataat cgagaaaatg gcatctttaa atgactctgt
     2461 aaattcagca ggaaacgcac ttgggaaagc ttttgtagat ggggcaaata tagcaatacg
     2521 aggagtaaac aaactggttg atttattaaa caaaatccct ggagtcaaca tcggaaaagt
     2581 tggagaagca acatttacac cagttaaagc tgataatagc tatatacagc aacaaatcaa
     2641 tagtttaaac aaatgggtag gaaatgcacc agagaaagtt gtactagagc gaatgggata
     2701 caaagatatt ggggcagcat ttgagaaagg aagtgctcta ggaacaaaat ggcaaaattc
     2761 cataactgat aaatttaaag atacttttga tattaataaa atgatagaaa atgcaaagaa
     2821 aaaattagga ttagatgacc tttgggatga caaatatgga ttaggagatg gatttggttc
     2881 tggtggactt aattctccac tcagcgacgc agcaaaagga acaaaggata cagcaggaaa
     2941 cactgcaaag atggctaaaa caatgg
//
LOCUS       DAFAZV010000129         2913 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFAZV010000129 DAFAZV010000000
VERSION     DAFAZV010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2913)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2913)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2913
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.133"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            23..913
                     /locus_tag="KOU88_004074"
     CDS             23..913
                     /locus_tag="KOU88_004074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3213881.1"
                     /translation="MAKLTLEHIKGNTYYIPLPTIVGVYVDGKDAILIDSGNNKDTAR
                     QVLRLLEEHNLNPKLIINTHSNADHIGGNAYLKNQTKCKIATTKIEGYFTENPILESA
                     FLYGGYPSKALKNKFLLAKESEVDYIIPSNGKIVDTELEVISLPGHYFEMIGVRTPDN
                     VLFVADSLTPENIITKYHFFFLLDIDSQFKTLEKLRMLEADFFVPSHSVKTTDIKSLI
                     NINKKKMEEIIDNIKKVCYEPVMIDEVIEKMCDLYNVKLDANQYVLVGSTIRSYITYL
                     YENNMVEYIFDGGKMMIKAV"
     gene            1131..2885
                     /locus_tag="KOU88_004075"
     CDS             1131..2885
                     /locus_tag="KOU88_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp23"
                     /protein_id="HBK3213882.1"
                     /translation="MYIMNKKFKKFSKKLSILILVLTMFLFNNLTANAQIKEDSIIGI
                     DRYETAGLIADRQTYDTVILVNGDKNLSDGLSSSGLAGAINAPILLTKKSEIPKATLN
                     RLDNKSLNVVKKVYIIGGYNTIENSVEKDIKRKGIQVERINGNNRIETSYNVVKKINE
                     VSSVKEVMLTNGFVGEADAMSIAPVVAKNKGAIILTDGKSVPFKTESLNVYAIGGKSA
                     INEDLVNETKATRIGGNDRFETNKKVMEKFYNGATDFYITNGYQLVDALTLSPLAKEK
                     PIVLVADGSNKGILKGAKSITKVGGIDANIYKQCLDMIKYNNMDMTPNILKHLTSVEG
                     NEVSEILIESDNLGVVVEKTNTNKFEFDYVSVTNEKNCTFSVYKENSSNNIKNGKLVV
                     SAKKKIDKKDSDLQDMNGDNMINANKDRMVNVIKIGVPDKMYSNFKVDVESGSVELYN
                     IKGGATVDVNDGIANIVDNNVTNPFNINTNSGISGVTAETISSEIKFRANNGIVNVTA
                     TNINGNISLFGSDNKGTFDGIFKLNLKKEPSNLHLKLIGNGINKLPEGWSKNYILGNG
                     QPIIEVKNNGINNISIGE"
BASE COUNT         1213 a          266 c          514 g          920 t
ORIGIN      
        1 aaatttaaag ggaggttata aaatggctaa attaactcta gaacatataa aaggaaatac
       61 atattatatt ccactcccta caatagtagg tgtatatgta gatggtaagg atgcaatttt
      121 aattgacagt ggaaataata aggatacagc tagacaagtt ttaagattat tagaagaaca
      181 taatttaaat cctaaattaa taataaacac tcattcaaat gcagaccata taggaggaaa
      241 tgcatatttg aagaatcaaa caaaatgcaa gattgctacg actaaaattg aaggatattt
      301 tacagaaaat ccaatattag aatcagcatt tttatatggt ggctatccaa gtaaagcact
      361 gaagaataaa tttttattag caaaggaaag tgaagttgat tatattatcc cttcaaatgg
      421 caaaattgta gatacagaac ttgaagtgat ttctcttcca ggtcattatt ttgaaatgat
      481 tggtgttaga actccagata atgttttgtt tgttgcagat agtcttacac cagagaatat
      541 aattactaaa tatcattttt tcttcctact ggatatagat tcacagttta agacactaga
      601 aaaattgaga atgttagagg ctgatttctt tgttccaagt cactctgtca aaactacaga
      661 tataaaaagt ttaattaata ttaataagaa gaagatggaa gaaataatag ataatattaa
      721 aaaggtttgt tatgagccag ttatgattga tgaagttatt gaaaaaatgt gtgatttgta
      781 caatgtcaag cttgatgcta atcaatatgt gttggttgga agtacaatac gttcttatat
      841 aacttattta tatgagaata atatggttga atatatattt gatggtggta agatgatgat
      901 aaaagctgtg taaatagtaa taattttcaa attatatgat gaaattgttt tagtatgact
      961 gttatttgaa aagtaatata aaaaaattta tataaataag ctaagatgat tgatataaag
     1021 ttactgataa ttttaaggta atatatacgt tactataata ttatgttatt atttgtaaat
     1081 aaggggataa tttataagca aattaaagac cttaatttac aggaggaata gtgtatatta
     1141 tgaataaaaa attcaaaaaa ttcagtaaaa aactaagtat attaatttta gttttgacta
     1201 tgtttctttt taataattta actgcaaatg cacagattaa agaagattca ataataggaa
     1261 ttgatagata tgaaacagca ggacttatag cggatagaca aacttatgat actgtaatat
     1321 tagttaatgg agataaaaat ttatctgatg ggctttcatc aagtggatta gctggagcta
     1381 ttaacgcacc aatacttttg actaaaaaaa gtgaaatacc aaaagctact ttaaatagac
     1441 tagataataa gagtttaaat gttgtaaaaa aagtatatat aattggtggt tataatacta
     1501 ttgaaaattc agtagaaaaa gatataaaaa gaaaaggtat tcaagtggaa agaataaatg
     1561 gtaacaatag aattgaaact agttataatg tagttaaaaa aataaatgaa gtaagtagtg
     1621 taaaagaggt aatgcttaca aatggatttg taggagaggc tgatgctatg agtatagcac
     1681 ctgtagttgc aaaaaataaa ggagctataa tacttacaga tgggaaatca gttccattta
     1741 agactgaaag tttaaatgtt tacgctatag gtggcaaatc tgcgataaat gaggatttag
     1801 taaatgaaac taaagcaact agaatcggag gaaatgatag atttgagacc aataaaaagg
     1861 taatggaaaa gttttataat ggagcgacag atttttatat aacaaatgga tatcaattag
     1921 tagatgcact aacattatct cctttagcca aagaaaaacc aatcgtttta gttgctgatg
     1981 gaagtaataa aggtatttta aaaggagcta aaagtataac aaaagttgga ggtattgatg
     2041 ccaatatata taaacagtgt ttagatatga ttaaatataa taatatggat atgactccaa
     2101 atattttaaa acacttaact tcagttgaag gaaatgaagt ttctgaaata cttatagaat
     2161 cagataattt aggtgtggtt gttgaaaaga cgaataccaa taaatttgag tttgattacg
     2221 taagtgtaac taatgaaaaa aattgtactt tttctgtata taaagaaaat tcttctaata
     2281 atataaaaaa tggaaagcta gttgtaagtg ctaagaaaaa aatagataag aaagatagtg
     2341 atttgcaaga tatgaatggc gacaatatga taaatgcaaa taaagatagg atggtaaatg
     2401 tgataaaaat tggagttccc gataaaatgt attctaattt taaagtagat gttgaaagtg
     2461 gttcagtaga actttataat attaaaggag gagctactgt tgatgtcaat gacgggattg
     2521 ctaacattgt tgataacaat gtaacaaatc ctttcaatat aaatactaat agtgggattt
     2581 caggtgtaac agctgaaact atatcatctg aaataaaatt tagagcaaac aatggaattg
     2641 taaatgtaac agctacgaat ataaatggca atataagttt atttggaagc gataataaag
     2701 gtacctttga tggaatattt aaattaaatc tgaaaaaaga accatcaaat ttacacttga
     2761 agttaattgg aaatgggata aataaattgc cagaaggttg gtctaaaaat tatattttag
     2821 gaaatggaca accaattatt gaagttaaaa ataatggcat aaataatata tcaattggag
     2881 aataaaaaca tatgaaaata aagtttatat agt
//
LOCUS       DAFAZV010000130         2771 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFAZV010000130 DAFAZV010000000
VERSION     DAFAZV010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2771
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.134"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            28..822
                     /locus_tag="KOU88_004076"
     CDS             28..822
                     /locus_tag="KOU88_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBK3213883.1"
                     /translation="MEKKEEIPIETKSFRMELGNRLEGLVAELFTEETGLKVRNVNGM
                     LKNEKYPFAIANIDRAIVGEKAFLECKTTNSFSIKEWENGVPLHYEIQCLHYMAVTGA
                     THCYIAALLGNEKFVWHKINRDNEVIKNLMKIESEFWEENVLKDILPIPDGSDAYSEF
                     LKTRYKNSVKEKIELNLLEDGISKLKRYDDIVLQMKELKGEKQLIEQEIQSEMREFEL
                     ATLGGRIITWKGATKRSIDTKRLREEMPDIAEKYTNISSYRTFKIK"
     gene            835..1668
                     /locus_tag="KOU88_004077"
     CDS             835..1668
                     /locus_tag="KOU88_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBK3213884.1"
                     /translation="MASEKAKGALEKKVSGANTVKVSPSKGMEQLMNKMASQIKKALP
                     SMVSSERFQRVALTAFSNNPRLQSCEPMSFIAAMMESAQLGLEPNTPLGQAYLIPYGN
                     KVQFQIGYKGLLELAQRSGKIKTIYAHKIRENDKFEIKYGLHQDLVHEPKLNGDRGEI
                     IGYYAVYHLDTGGHSFSFMTKEEIIEFAKSKSKSYSSGPWQTDFDSMAKKTVIKQLLK
                     YAPLSIELQKAMVGDETIKSEIDEDMSMVVDESESLEVDFEVKENMDGKVSVEEAINV
                     D"
     gene            1683..2621
                     /locus_tag="KOU88_004078"
     CDS             1683..2621
                     /locus_tag="KOU88_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213885.1"
                     /translation="MNEDKSVIEKLNILSGGYGLMPRIIARDRWLTVGARMLYSYLTS
                     FAGNDGTCFPSRDLICYELDISKDTFTKYKKELEMSGYIRVHKNKSKQGKMQNNIYEI
                     VFDRTYIDECISKRGLKEEKKKKKPCTKKQDTEPYPKNVDMEPCPTFPDTTQPDTENM
                     DTNSNSINSNSINNMYIVKQPVDNFLKEFKKLYEENIGVIYPVTAEWLLEVSNEVDIR
                     VFKRAIEICAEKMNMNLAYLKGILKKWKDANITTYEQLESYRLQQENKKTKKVVNNHV
                     SKNKFANFEQTFTKYSENELDDIIKKSQKEKFGVGS"
BASE COUNT         1169 a          291 c          569 g          742 t
ORIGIN      
        1 ccctggaaaa cttctgttca agtatatata gaaaagaaag aagaaatacc aatagaaact
       61 aaaagtttca gaatggaatt aggcaataga ttagaaggat tagttgcaga actttttaca
      121 gaagaaactg gtcttaaggt ccgtaatgta aatggaatgt tgaaaaatga aaagtatcct
      181 tttgcaatag ctaatataga cagagctata gtaggagaaa aagcattttt agaatgtaag
      241 acaacaaata gtttttctat aaaagaatgg gaaaatggag ttccacttca ttatgaaata
      301 caatgcttac actatatggc tgtcacagga gctacacatt gttatatagc agcacttctt
      361 ggaaatgaaa agtttgtatg gcacaagata aatagggata atgaagtaat taaaaatcta
      421 atgaaaatag agagtgaatt ttgggaagaa aatgtattaa aagacatttt accaattcct
      481 gatggttcag atgcttatag tgagtttctg aaaacaaggt ataaaaactc agtaaaagag
      541 aaaatagaac taaatctact tgaagatggt atatcaaagt taaaaagata tgatgatata
      601 gttttacaaa tgaaagaact aaaaggagag aaacagctaa tagaacaaga aatacaaagt
      661 gaaatgagag agtttgagtt agctacatta ggcggaagaa taataacttg gaaaggagct
      721 actaaaaggt ccattgatac caagagatta agagaagaaa tgcctgatat agcagaaaaa
      781 tatacaaata taagttcata cagaacattc aaaataaaat agggggtaat atatatggct
      841 agtgaaaaag caaaaggagc attagaaaag aaagtttcag gagcaaatac agtcaaggta
      901 agtccaagta aaggtatgga gcaacttatg aataaaatgg caagtcagat aaaaaaagct
      961 ttacctagta tggtttcaag cgagagattt caaagagttg ccctaacagc ttttagtaat
     1021 aatccaaggt tacaatcatg tgaacctatg agttttatag cagcaatgat ggaatcagct
     1081 caattaggtc ttgagcctaa tacgccttta ggtcaagcat atttgatacc atatggaaat
     1141 aaagtgcaat tccaaattgg gtataaagga cttttagaat tagcacaaag aagtggaaag
     1201 ataaaaacta tatatgctca taaaataaga gaaaacgata aatttgagat taaatatggg
     1261 cttcatcaag acttagttca tgaacctaaa ttaaatggtg atagagggga aataattgga
     1321 tattatgcag tatatcattt ggatacagga ggacatagtt tttcttttat gactaaagag
     1381 gaaattatag aatttgcaaa gagtaaaagt aaaagttata gtagtggacc atggcaaaca
     1441 gattttgatt caatggctaa aaagacagtt ataaaacagt tattaaaata tgcaccactt
     1501 agtatagaat tacaaaaagc tatggtaggt gatgaaacaa taaaatctga aatagatgaa
     1561 gatatgagca tggtcgtaga tgaaagcgaa agtttagaag ttgatttcga agtaaaagaa
     1621 aatatggatg gtaaagttag tgtggaagaa gctataaatg ttgattaagt aggtgaggca
     1681 ccttgaatga agataagtca gttatagaga aattaaatat attaagtggt ggatacggtc
     1741 ttatgccaag aataatagca agagataggt ggttgacagt tggcgctaga atgctgtatt
     1801 catatctaac tagttttgca gggaatgatg gaacatgttt tccatctagg gatttaattt
     1861 gttatgaact agatatatca aaagacacat ttacaaagta caaaaaagag ctagagatga
     1921 gtggctatat aagggttcat aagaataaat ccaaacaagg caagatgcaa aacaatatat
     1981 atgaaatagt atttgataga acttatatag atgaatgtat ttctaagaga ggtttaaaag
     2041 aggagaaaaa gaagaaaaag ccatgtacta aaaagcaaga cacggaaccg tatcctaaaa
     2101 atgtagacat ggaaccatgt cctacttttc cggacacgac tcagccggac acggaaaata
     2161 tggacactaa tagtaacagt attaatagta acagtattaa taatatgtat atagtaaagc
     2221 aacctgtgga taacttttta aaagaattta agaagctgta tgaagaaaat ataggagtaa
     2281 tatatccagt tacagctgaa tggttattag aagtatctaa tgaagtagat ataagagtat
     2341 ttaaaagagc tatagagata tgtgctgaaa agatgaatat gaatctagca tacttaaaag
     2401 gtatccttaa aaaatggaag gatgcaaata ttactacata tgagcaactg gaatcatata
     2461 gattacagca agaaaataag aaaacaaaaa aagtagttaa taaccatgtg agtaaaaata
     2521 agtttgctaa ctttgaacaa acatttacta agtattcaga gaatgagctt gatgacatta
     2581 ttaagaaaag ccaaaaagag aagtttggag taggaagtta aaatattgga gggatgaaag
     2641 atggagttaa aatttagaga atggaataaa aatggtaaag aaatgtatag ttatgatgaa
     2701 atggtgtgct attctaaaaa tttgcttaga gagtgggttt atagtggtgt ttatttacca
     2761 acaagcaatg a
//
LOCUS       DAFAZV010000131         2637 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFAZV010000131 DAFAZV010000000
VERSION     DAFAZV010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2637)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2637)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2637
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.135"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(326..715)
                     /locus_tag="KOU88_004079"
     CDS             complement(326..715)
                     /locus_tag="KOU88_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK3213886.1"
                     /translation="MVLNLDFNSDKSIYVQIKEEITKAIASGELKINESLPSVRSMAE
                     NIGVNLHTVNKSYNELKEEGFLNIDRRKGAIVAQLPMKIDNTTRQKNKLDLELLVAKS
                     YLSGISKEEFLSLSSSLFDKYEVKYYE"
     gene            907..1353
                     /locus_tag="KOU88_004080"
     CDS             907..1353
                     /locus_tag="KOU88_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213887.1"
                     /translation="MLTYLMKRQMHKKDDGMSKPMMITGAVITGVGAYAVYKMVKSHK
                     SNSQMVNTNYYGNSDYDDYKYDEFDYDCDCRDTKQDYEYEELKKKVKEFNSRRINCEN
                     CPHVSQEEMMQYVNSVKDVKEEIDLHEDAKKDNIYKEDEYKKYEEE"
     gene            1617..2342
                     /locus_tag="KOU88_004081"
     CDS             1617..2342
                     /locus_tag="KOU88_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213888.1"
                     /translation="MKRKEIVMLKLLIVEDDSTISFGIKYALEQEGFSIDISKDLSSG
                     KEMISSNEYSMILLDVTLPDGTGYELCQYIRGFSQVPIIFLTACDEEVNIVMGLDIGG
                     DDYITKPFRIRELISRIKAVLRRKGNTSEENKKILKFGDLSIYTLEARVYKNDKEIFL
                     TSVEYKLLLILIQNKNTVLSRTQILEKLWDVTYDFVNDNTLTVYIKRLREKIGDDLCE
                     PIYIETVRGIGYKWIGSENSVSI"
     gene            2329..>2637
                     /locus_tag="KOU88_004082"
     CDS             2329..>2637
                     /locus_tag="KOU88_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009896390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK3213889.1"
                     /translation="MFLYNPEVKKFLSKYVTLMFIVIIISIGFSIINVSLTKEMVVRN
                     NQAIIGTLSSKYPNLESQIVDIITQGKSMENIDYGQKILIKYNYDKSIRINSEPIISK
                     L"
BASE COUNT         1083 a          261 c          385 g          908 t
ORIGIN      
        1 tgatttaagc ttcttagctt ttttatgtgt atgaatatat agtatacttt catataataa
       61 aaaacctata ataccaataa aataggaaag ttccaattta ttaaatgtaa aaaccagaat
      121 aaaaactaat ataaagtcta taataaaacc taaagataat agttttttaa attttttatc
      181 taactttata aagtaattat aatttttatg ctcttggtct atagaaactc catagatatg
      241 ttttttacct acaaaatagg gcataaaata aaatgtagta tacatcaaaa ttagaactgg
      301 aaatattgta aatagacatt caatcttact cataatattt cacctcatac ttgtcaaata
      361 aacttgaact tagtgacaaa aattcttctt tactaatacc tgataaataa gattttgcca
      421 ccaataattc caagtcaagt ttattttttt gacgagttgt attatctatt ttcattggta
      481 gttgagctac aatagcacct tttcttctat caatatttaa gaatccctct tcttttaatt
      541 cattgtagga tttgttcact gtatgtaaat ttacaccaat attttcagcc atacttctta
      601 cagatggaag tgattcattt attttcaatt ctcctgaagc tatagcctta gttatttctt
      661 ctttaatttg tacataaata gatttatcac tattaaaatc taaatttaaa accataaaaa
      721 acctccatta tgctttataa atgaaaacga ttgttatata catagtataa cataaaaaat
      781 aataacaaac acaaaatata agtttatatt ttgtaaaaat tgtaatttaa aaaataacat
      841 aatttttatt aaaataatac agatactatt tatagataga aataaaaatt agaaaggaga
      901 aaaaatatgt taacatattt aatgaaaaga caaatgcata aaaaagatga tggaatgagt
      961 aaaccaatga tgattacagg agctgtaatt acaggtgtag gagcatatgc tgtatataaa
     1021 atggtaaaaa gccataaatc taattctcaa atggtcaata caaattatta tggaaatagc
     1081 gattatgatg attataaata tgacgaattt gattatgact gtgattgtag agacacaaaa
     1141 caagattatg aatatgaaga attaaaaaaa aaagtaaaag aatttaattc aagaagaata
     1201 aattgtgaaa attgtccaca tgtttctcaa gaagaaatga tgcaatatgt aaatagtgtt
     1261 aaagatgtaa aggaagagat tgatttacat gaagatgcta aaaaagataa tatttacaaa
     1321 gaagatgaat acaaaaaata tgaagaagaa taagtaatat tttgtataac tgaacaaata
     1381 gtaatgtcaa attatttaat atctagtttt aatatgtaag ttgtaactta acttgaaaga
     1441 atcagtatca ttctttagat agttaagtaa caacttacat tttattttta taaattttaa
     1501 tagttctttg tgactatttt gtaattttag aaatatttta gtatccaggg taattgtgta
     1561 taataaaact tgtatagata gatagtatga aattaagcag atagtttaaa attaaaatga
     1621 aaagaaagga aatagttatg ttaaagttgt tgatagttga agatgatagt actatatctt
     1681 ttggaataaa gtatgcttta gaacaagaag gatttagtat agatatatca aaggatttat
     1741 ctagtggaaa agaaatgatt tcttctaatg aatatagcat gatactgttg gatgttacat
     1801 tgccagatgg aactggttat gagctttgtc aatatataag aggattctct caggttccta
     1861 taatattctt gactgcttgt gatgaagaag taaatattgt aatgggtctc gatataggtg
     1921 gagatgatta tataacaaaa ccttttagaa ttagagaatt aatatccaga ataaaagctg
     1981 ttttaagaag aaaaggtaat acttcagaag aaaataagaa aatacttaaa tttggagatt
     2041 taagtatata tacattagaa gctagagtat ataaaaatga taaagaaata tttctgacat
     2101 cagttgaata taaacttctt ttaattctta tacagaataa aaatactgtt ttaagtagaa
     2161 ctcaaatatt ggaaaaactt tgggatgtaa cttatgattt tgtaaatgac aatactctca
     2221 ctgtttatat aaaaaggctt agagaaaaaa taggtgatga tttatgtgaa ccaatctaca
     2281 tagaaactgt aaggggaatt ggttataaat ggataggaag tgaaaatagt gtttctatat
     2341 aatccagaag tgaagaagtt tttaagtaag tatgttactt tgatgtttat tgttatcata
     2401 atatctattg gatttagcat aatcaacgtg tccttaacta aagagatggt tgtaagaaat
     2461 aatcaggcta taataggaac tttatcaagc aagtatccaa acttagaaag tcagatagta
     2521 gacataataa ctcaagggaa gtctatggag aacatagatt atggtcagaa aatattaatt
     2581 aagtataatt atgataaatc tattaggata aactctgagc ctattatttc taaatta
//
LOCUS       DAFAZV010000132         2632 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFAZV010000132 DAFAZV010000000
VERSION     DAFAZV010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2632)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2632)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2632
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.136"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..806)
                     /locus_tag="KOU88_004083"
     CDS             complement(<1..806)
                     /locus_tag="KOU88_004083"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213890.1"
                     /translation="MALISGNFKGKIDNKSIWDYMHKLDYKLETLEERKKFIDELLNL
                     KNIDELKFSDDEFWQEVFDKGICKANLNTTDVLWSETNISHFLEKVGTYLLAKDDKKE
                     EKENIKVYDSYSEFKRSMQQEKKMRKHAEVVEFDVEDNENSNGKPVRILKNQKNFKLS
                     PDIKISKKDRLKYSEIEDYYKYKQYLLNLKNDKEHRENLSKSINSNNVKLRIKKGGDI
                     YRFAIKQLPLVQDDMLQVKLQKDKNIIWKAPLKDSCNDINIDCDLIDMFDP"
     gene            complement(766..960)
                     /locus_tag="KOU88_004084"
     CDS             complement(766..960)
                     /locus_tag="KOU88_004084"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213891.1"
                     /translation="MVNKNIKILREDYSEFLDDWNIIGKRNIYKCPECQYHGNKCDRH
                     NNSEGVSYGFDKWQFQRENR"
     gene            1560..1799
                     /locus_tag="KOU88_004085"
     CDS             1560..1799
                     /locus_tag="KOU88_004085"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213892.1"
                     /translation="MVKEDIFKSKSISLKAKGLYGTISAFKNEPYFSKQFLMDYLDLG
                     AYSFRMAWNELKDKGYLEVNKKFENGIFVYEYKLY"
     gene            1809..2435
                     /locus_tag="KOU88_004086"
     CDS             1809..2435
                     /locus_tag="KOU88_004086"
                     /inference="COORDINATES: protein motif:HMM:NF025107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213893.1"
                     /translation="MNNIIKIKDGEVLDVRLEEDSILSDGYGISPKFLMRNKDIPIYS
                     KAIYAYLASFAGNKKYCHPRMETIYGELNISKNAFIKYVEVLKENGFIKVYRIQNENN
                     LYGNNVYEIAMSKSKIRENAESYMKTKREKKKSKKSPDEVAASTDDSKRKTLNSINDN
                     NIITQKEKDIQVLKENGFTELEIYSMSEKEIASGASKMREIIKKQQKK"
BASE COUNT          897 a          343 c          345 g         1047 t
ORIGIN      
        1 gggtcaaaca tatctattaa atcacagtct atattgatgt cattacaact atcttttaat
       61 ggagctttcc aaattatgtt tttatctttt tggagtttga cttgtaacat atcatcctga
      121 actagtggta gttgtttgat tgcaaacctg taaatatccc cgcctttttt aattcttaat
      181 tttacattat ttgaatttat actttttgat aaattttctc tatgctcttt atcatttttt
      241 aagtttaata aatactgttt atatttataa taatcttcta tttcagaata ttttaatcta
      301 tcttttttac ttatttttat atctggagat agtttaaaat ttttctgatt ttttagtatt
      361 cttactggtt ttccatttga attttcattg tcttcaacat caaattcaac cacctctgca
      421 tgttttcgca tttttttctc ttgttgcata ctccttttaa attctgaata agagtcatat
      481 acttttatat tttctttttc ttctttttta tcatcctttg ctaatagata tgtacctact
      541 ttttctaaga aatgacttat attggtttct gaccataata catctgttgt atttaaatta
      601 gctttgcata ttcctttatc gaatacttct tgccaaaatt catcatcact gaatttaagc
      661 tcatctatat tttttagatt taataattca tcaataaatt tctttctttc ttctaatgtt
      721 tctaatttat agtctaattt atgcatgtag tcccaaatac ttttattatc tattttccct
      781 ttgaaattgc cacttatcaa agccatagct taccccctca ctattattat gtctgtcaca
      841 tttattccca tgatattgac attctggaca tttatatata tttctttttc caattatatt
      901 ccagtcatct aaaaattcac tataatcctc tcttaatatt tttatatttt tgtttaccat
      961 cttctagtcc tttcatcttt ttgtattctt tacttttctt catattttaa cctccgtttc
     1021 aattttgttt tttaatttta tttagttgtt aaatgttttt catatataaa tttcctccta
     1081 ttaatttaat attttatcta taattatata ttaacatttt atattatttt tgtcaattta
     1141 gtattttatt cagttttatt ccctgttgat aagctgttag taagttgttg ataacatgtt
     1201 gataagttgc aattttatta acaatttgta tttttatctg tgcataacta tataattttt
     1261 aaattgtttc agatacttta atttttcgat gtaccatctc gtggtatatc gaggcaaaaa
     1321 tcgaaaaaac gttgaaatat agcgattctt tcgatgtacc atctcgtggt acatcgaatt
     1381 tttcgatatc ccatgctatg ggcgtaccat gagatggtat attaatataa acagttttta
     1441 atatatttgt ttttgtattt atttgtttat gtaaagggaa aaattacctt gaaaaaatgg
     1501 gaattataaa ttataataag tttaaaataa aaaaaatagg agggtgtaaa aattagacta
     1561 tggtaaaaga agatatattc aaaagtaaaa gtattagctt aaaagctaaa ggtctttatg
     1621 gaactatctc agcatttaaa aacgaacctt acttctctaa acaatttttg atggactatt
     1681 tagatttggg agcatattcg tttagaatgg catggaacga attgaaagac aagggctatc
     1741 ttgaagttaa taaaaaattt gaaaatggaa tatttgtata tgaatacaaa ttgtactagg
     1801 agtaacttat gaataatata ataaaaatta aagatggtga ggttttagat gttagactag
     1861 aggaagatag tattctttcg gatggttatg gtatatctcc aaaatttctt atgagaaata
     1921 aggacatacc tatttactca aaagctattt acgcttatct ggctagtttc gcaggtaata
     1981 aaaaatactg tcatccaaga atggaaacaa tctatggaga gttgaacata agtaaaaatg
     2041 cttttataaa atatgttgag gtcttaaagg aaaatggatt tattaaggtt tatagaatcc
     2101 aaaatgaaaa taatttatat ggaaataacg tgtatgaaat tgcaatgtct aagtcaaaaa
     2161 ttcgagaaaa tgcagagagt tacatgaaga cgaaaaggga aaagaagaaa agtaaaaagt
     2221 cacctgatga agtagcagct tcaacagatg actcgaaacg aaaaacttta aattcaatta
     2281 atgataataa tattataaca caaaaagaaa aagatataca agtactaaaa gaaaatggat
     2341 ttactgaatt agaaatatat tctatgtctg aaaaagaaat tgcatcaggt gcgagtaaga
     2401 tgagagagat aataaaaaaa caacaaaaga aataataaaa aggtcactaa attagtgacc
     2461 tttaaaatct attctaaacg attttatttc tgaatatgaa ttaattatca tggacgggca
     2521 tggaactgtc ttaaaatggc tctcattaaa tatttttagt attattgttc aaggtatcca
     2581 attacatttg catagaaacg agaatcatca tcgacttcta gttgtttact ta
//
LOCUS       DAFAZV010000133         2604 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFAZV010000133 DAFAZV010000000
VERSION     DAFAZV010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2604
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.137"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..204
                     /locus_tag="KOU88_004087"
     CDS             <1..204
                     /locus_tag="KOU88_004087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213894.1"
                     /translation="KATIVEAKATTTKVLIGKDLETGRVEASEFKNQVAGQLVMDIPD
                     SEETNETEENSASVIDFRNASSK"
     gene            256..960
                     /locus_tag="KOU88_004088"
     CDS             256..960
                     /locus_tag="KOU88_004088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213895.1"
                     /translation="MIRNAIEYLVKLGKRETVCVDGFKYTTDALEIIEEPKANELEIT
                     TLSGLVDYIKSGIDHKEDELLLIQVLTPRKVLLKSPLRKNRDRETYIECVALLPEKRF
                     DRPLDLDSFNIMLQSAFIKNNDRDTLLKIAGNIQESTVKNVGDDGVSQSVTIKTGVAS
                     VSEAIVPNRVKLIPYRTFQEVEQPESEFIFRMSSGPAAGLYEADGGAWKNQAMLNIKA
                     YLQEELKDFKNVNIIA"
     gene            1018..1200
                     /locus_tag="KOU88_004089"
     CDS             1018..1200
                     /locus_tag="KOU88_004089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213896.1"
                     /translation="MKSISHMNILERAEFTDKIANAIMSANKEIERGCAFNEAVEIVK
                     QMEYRENKYNEGDIAI"
     gene            1197..1574
                     /gene="ssb"
                     /locus_tag="KOU88_004090"
     CDS             1197..1574
                     /gene="ssb"
                     /locus_tag="KOU88_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK3213897.1"
                     /translation="MNNVVLVGRLARDPELRYIPEYGTPVATFALAVDRGYAKKDGTR
                     EVDFIPIEVMGGSAEFCANYLTKGRMVSIQGQIRIEKYEKDGEKKTFTKVRTKIVNAL
                     DHKPKDEEKEIGFQVLDDEDIPF"
     gene            1552..2136
                     /locus_tag="KOU88_004091"
     CDS             1552..2136
                     /locus_tag="KOU88_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3213898.1"
                     /translation="MMKIFHFKLDGDYMRSLEEKNKLFEDNINLVHFIINRYFKSFLR
                     RYPYLKEDLFQEGYIGLYKTTCCFDESKGKFSTIAFSYISGHLKRFTTGYVKKHYRND
                     IDSFEKCIYRDNYGEEIRIEDRLAGNENVDIENVRVIRSCIKRSEIKDIQKIVCLREK
                     GYTQQEISKVLGTSQTSIYRRLKKLKTEINILGK"
     gene            2165..2323
                     /locus_tag="KOU88_004092"
     CDS             2165..2323
                     /locus_tag="KOU88_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213899.1"
                     /translation="MKTKIIGGRENECPICNGNIFKIETLIGIVWQCKDCGCMYQDMS
                     SKESKRGY"
     gene            2326..>2604
                     /locus_tag="KOU88_004093"
     CDS             2326..>2604
                     /locus_tag="KOU88_004093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213900.1"
                     /translation="MSCVIKCDFCGETIAEILNIKVFRIDDEGNIMSIGKDVCDKCYD
                     RLFRSNLNKKMTNYEKIKNMSKIEMAEFLANGGSGCTSCAYDFQECLGG"
BASE COUNT         1107 a          230 c          527 g          740 t
ORIGIN      
        1 aaagcaacta tagtagaagc aaaggctaca acaactaaag ttctgatagg aaaagattta
       61 gagacaggaa gagttgaagc gtctgaattt aaaaatcaag tagcagggca gttggtcatg
      121 gatattccag atagtgaaga aactaatgaa acagaagaaa atagtgctag tgtaattgat
      181 ttcagaaatg caagttcaaa gtagtttaag aaagtaagta aaatataaat ttaaataaaa
      241 aaggagaata aaaaaatgat aagaaatgca atagaatatt tagttaagtt aggaaaaaga
      301 gaaacagtat gtgtagatgg gtttaagtac acaacagatg cattagaaat aatagaagaa
      361 ccaaaagcta atgaattaga aataactaca ttgagtggtt tagtagatta tataaaaagt
      421 ggcatagatc ataaagaaga tgaattgtta ttaatacaag ttctaactcc aagaaaagtg
      481 cttttaaaat ctcctttgag aaaaaataga gatagagaga catatattga atgtgttgca
      541 ctactaccag agaaaagatt tgacagacct ttagacttag atagttttaa cataatgcta
      601 caatcagcat ttataaagaa taatgataga gatacacttt taaaaattgc aggtaatatc
      661 caagaatcta cagtaaaaaa cgtgggagat gatggagttt ctcaatctgt aacaataaaa
      721 acaggtgtcg ctagtgtatc agaagcaata gttccaaata gagtaaaatt gattccttac
      781 cgtactttcc aagaagtaga gcaaccagaa agtgaattta ttttcagaat gagttctgga
      841 ccagcagcag gattatatga agcagatggt ggagcatgga aaaatcaagc aatgttaaat
      901 attaaagcgt acttgcaaga agaattaaaa gattttaaaa atgtaaatat aattgcttaa
      961 ttgaaaatct aagaggactt attataagtc ctcttagtaa aacaaggagg gagttaaatg
     1021 aaaagtattt ctcatatgaa cattttagaa agagcagaat ttacagacaa aattgctaat
     1081 gcaattatgt ctgcaaataa agaaattgaa agaggttgtg cctttaatga agcagttgag
     1141 attgtaaaac aaatggaata tagagaaaat aaatacaatg aaggagatat tgcaatatga
     1201 ataatgtagt tttagttgga agattagcaa gagatccaga attaagatat ataccagagt
     1261 atggtactcc agttgctact tttgcattgg cagttgatag gggttatgca aaaaaggatg
     1321 gaactagaga agttgatttt ataccaattg aagttatggg aggatcagca gaattttgtg
     1381 ctaattatct cacaaaagga agaatggttt caattcaagg ccaaataagg atagaaaaat
     1441 atgaaaaaga tggagagaaa aaaactttca caaaagtaag aacaaaaatt gttaatgcgc
     1501 ttgatcacaa gccaaaggat gaagaaaaag aaataggctt tcaagtttta gatgatgaag
     1561 atattccatt ttaaattgga tggtgattat atgagaagtt tagaagagaa aaataaatta
     1621 tttgaagata atataaatct tgtacatttt attataaata gatatttcaa atccttttta
     1681 agaaggtatc catatttaaa agaagattta tttcaagaag gatatatagg attatataaa
     1741 acaacatgtt gctttgatga aagtaaagga aaattttcta caatagcatt ttcgtatata
     1801 tcaggacatt tgaaaagatt tacgactgga tatgttaaga aacattatag aaatgatata
     1861 gatagttttg aaaagtgtat ttatagagat aattatggag aagagataag aatagaagat
     1921 agattggctg gcaatgaaaa tgtagatata gaaaatgttc gtgttattag atcttgtata
     1981 aaaagaagtg agataaaaga tatacagaaa atagtttgtc taagagaaaa aggttatact
     2041 caacaagaaa taagtaaagt gcttggaact agccaaacgt caatatatag gagacttaaa
     2101 aaattaaaaa ctgaaattaa tatactaggt aaataataaa tgatttaagt ttattggagg
     2161 taaaatgaaa actaaaataa ttggtggtag ggaaaatgag tgtccaattt gtaatggtaa
     2221 tatatttaag attgaaacat taattggaat agtgtggcaa tgtaaggatt gtggatgtat
     2281 gtatcaagat atgagttcta aagaaagtaa aagggggtat taaagatgag ttgtgttata
     2341 aagtgtgatt tttgtggtga aacaatagca gaaattctaa acataaaggt attcagaatt
     2401 gatgatgaag gtaatataat gagtatcgga aaagatgtat gtgacaaatg ttatgacaga
     2461 ttatttagaa gtaacttgaa taagaagatg actaattatg aaaagataaa aaatatgagc
     2521 aaaatagaaa tggctgaatt tcttgcaaat ggcggaagtg gatgtactag ttgtgcttat
     2581 gattttcaag aatgcttagg cgga
//
LOCUS       DAFAZV010000134         2598 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFAZV010000134 DAFAZV010000000
VERSION     DAFAZV010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2598
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.138"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..337)
                     /locus_tag="KOU88_004094"
     CDS             complement(<1..337)
                     /locus_tag="KOU88_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK3213901.1"
                     /translation="MLENRKQIQKEIYLPIATYCLKDKQYYIKEYGALLIKSAENSDI
                     FNTHKNRILYKNKLDIQEIANELNVNKATIQRNIKKLEKLDFKILKIENTLNGIVYCL
                     PSENNIDLNK"
     gene            757..1944
                     /locus_tag="KOU88_004095"
     CDS             757..1944
                     /locus_tag="KOU88_004095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBK3213902.1"
                     /translation="MEKKEILMQPNNLIKSKYDFTNVENKLFYKILFNAQKQQNSSYV
                     TTISKEELKVFMKNNNDYEHKNIKEILNMFQQSVLEFDYIEETTGKLKTFGSGLINTY
                     ELDHTDQIYTIMMHEVLYNHITDFVKMQKKKNGYTAINLSVLFNFRGAYTQRLYTLFR
                     LWSRENKEVEIKYKLDELRFYLKLKDNVYPEYKYFKQNVLKRAMNEINKKGNMVVSIK
                     EEKRKNRKIDEIIFSVIDYEPRKYFDKDILVEDYIPKKKQDNEVSFSFYIPNENIFTT
                     GTIKLFKEDFKEFDFKKDVYLNAFNKSIAIAFERDNTDIINTKNYDFFKSTLSNKISE
                     VIIHQKDDLKFKEELDKYWDDEDVKKEEREVDYSKDPVRLETVRRNLFDQGLVNEEGY
                     YYK"
     gene            1964..>2598
                     /locus_tag="KOU88_004096"
     CDS             1964..>2598
                     /locus_tag="KOU88_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBK3213903.1"
                     /translation="MYYVYKYIDPATEECLYVGKTEDIYARHSSHLSNKEEDWCTKEL
                     ILKYIELPRRYNMDFFEVYLINELNPIFNKLSKGDMDTEHIFFDYKEEDWSTYSEEDF
                     KEKTKGKRRFRERKIDMKYEVSKKSINFLKRIEKLDAKVEMLYENNVLSVLYNFENMD
                     IEFCENELDINLISYDFETLERFGSCSLISVYPRWKEYTATNKKILINITL"
BASE COUNT         1071 a          223 c          397 g          907 t
ORIGIN      
        1 atttgtttaa atcaatatta ttttctgacg gcaaacaata tacaattcca tttagggtat
       61 tttctatttt tagaatttta aaatctaact tctctagttt ttttatattt ctttggattg
      121 ttgctttatt tacattcagt tcatttgcta tttcttgaat atcaagttta ttcttataca
      181 aaattctatt tttatgggta ttaaaaatgt cactattttc agcactcttt attaatagtg
      241 ctccatattc ttttatataa tattgcttat cttttaaaca atatgttgct attggtaagt
      301 aaatttcttt ctgaatttgt tttctgtttt caagcataaa aaattcttca tctccaatct
      361 tttataagaa attattttta gtaagtgttt aaagtatact agaaaaataa atactaaagt
      421 tttttaatat aaaaaaagaa tagttcagaa catcttttct agtctttaat agtttttaaa
      481 acagttttta aagtctttaa tagtttttag acaagctata ataattggta tatctaggtt
      541 tcagagatga aaggtcatca ttttaagggt caaaggtcat cattttaagg gtcaaaggtc
      601 atcattttaa gggtcgaaag gtcatcattt taagggtcaa aggtcatcat tttaagggtc
      661 aaaggtcatc attttaaggg tcaaaggtga gcgtctttca aaaatagttg acctttttat
      721 aaattaggta ttataattta tatgaggtga tagattttgg aaaaaaaaga aattttaatg
      781 caaccaaata atttaataaa aagtaaatat gattttacaa atgtggaaaa taaattattt
      841 tacaaaatac tttttaatgc tcagaaacag caaaattcat cttatgttac aactatatca
      901 aaagaagaac taaaagtatt tatgaaaaac aataatgatt atgagcataa aaatataaaa
      961 gaaattttga acatgtttca acaaagtgtt ttggaatttg actatataga agagacaact
     1021 ggcaagttaa aaacttttgg aagtggttta attaatacat atgaattgga tcatacagac
     1081 caaatttata caattatgat gcatgaagtt ctatacaatc atataactga ttttgtaaaa
     1141 atgcagaaaa agaaaaatgg atatacagct attaatttat cagtgttatt taattttaga
     1201 ggtgcatata ctcagaggtt atacacttta tttagactat ggagcagaga aaataaggaa
     1261 gtggagataa aatataagtt agatgaatta agattttatt tgaaattaaa agataatgta
     1321 tatccagagt ataaatattt taaacaaaat gttctaaaaa gagcaatgaa tgaaataaat
     1381 aaaaaaggca acatggttgt ttcaataaaa gaagaaaaaa gaaaaaatag aaaaatagat
     1441 gaaataattt tttctgtgat agattatgaa cctagaaaat attttgataa agatatattg
     1501 gttgaagatt atatacctaa aaagaagcag gacaatgaag tgtcttttag tttttatata
     1561 ccaaatgaaa atatttttac aacagggacg attaaactat ttaaagaaga ttttaaagag
     1621 tttgatttta agaaagatgt ttatctgaat gcttttaata agtctattgc tatagcattt
     1681 gaaagagata atactgatat tataaataca aagaattatg atttttttaa atcaacactt
     1741 tcaaataaaa taagtgaagt tataattcat caaaaagatg atttaaagtt taaagaagaa
     1801 ttagataaat attgggatga tgaagatgtt aaaaaagaag aaagagaagt tgattatagc
     1861 aaagatcctg tcagacttga aactgttagg agaaatttat ttgatcaagg tctagtaaat
     1921 gaagaaggat attactataa ataaaaattg gagaaaataa aaaatgtatt atgtttataa
     1981 atatattgat ccagctacag aagaatgttt atacgttgga aaaacagaag atatatatgc
     2041 aaggcattca tctcatttga gtaataaaga agaagattgg tgtactaaag aattaatatt
     2101 aaaatatatt gaacttccac gtagatataa tatggatttt tttgaagttt atttaataaa
     2161 tgaactaaat ccaatattta ataaactaag taaaggtgat atggatactg aacacatctt
     2221 ttttgattac aaggaagaag attggagtac atattcagaa gaagatttta aggaaaagac
     2281 aaagggaaaa agaagattca gagaaagaaa gatagatatg aaatatgaag taagtaaaaa
     2341 atctattaat tttttaaaga gaattgaaaa gttagatgcc aaggttgaaa tgttatatga
     2401 aaataatgtt ttaagtgtgc tatataactt tgaaaatatg gatatagaat tttgtgagaa
     2461 tgaattagat attaatttga tatcatatga ttttgaaaca ttagaaagat ttggaagttg
     2521 ttctttgatt tcagtttatc ccagatggaa agaatataca gcaacaaata aaaaaatact
     2581 tataaatata acattaga
//
LOCUS       DAFAZV010000135         2570 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFAZV010000135 DAFAZV010000000
VERSION     DAFAZV010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2570
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.139"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(73..543)
                     /locus_tag="KOU88_004097"
     CDS             complement(73..543)
                     /locus_tag="KOU88_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="HBK3213904.1"
                     /translation="MKYQVSLLAVKDIEVSKKFYKELFEQEIELDLGKNVTFKGGFAI
                     QEDFAWLTGINPDTVIQKSNNMELYFEVDDFDEFIEKLNYYKDVEFVHKPLKHEWQQR
                     VVRIYDPDKHIIEIGESMEVIARRYLSEGYSVEETSKIIQHPIEFVKQCENSKE"
     gene            complement(1277..1666)
                     /locus_tag="KOU88_004098"
     CDS             complement(1277..1666)
                     /locus_tag="KOU88_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213905.1"
                     /translation="MTIKKLPQSELKIMKFIWKSDSKVTSRDIVLGMEQKYQWKQTTT
                     LTLLSRLVVKRFLNSQKIDKYTHYEVLIKEKEYIGVETRDFFRNIHDSSIKSLLLSLH
                     ENINLSKDDILLIEEWIKNLKEEEKDV"
BASE COUNT          806 a          470 c          154 g         1140 t
ORIGIN      
        1 actagtccta tatattatct tgaattagtt ctaccacaat taatttctac taaataatta
       61 taatttaaac aatcattcct tactattttc acactgcttt acaaattcaa ttggatgttg
      121 aattatttta gaagtttctt ctacagaata tccctcagat aaatatcttc tagctataac
      181 ttccatagac tctcctatct caataatatg cttatctggg tcataaatac gcactactct
      241 ttgttgccat tcatgtttta gtggcttatg gacaaactct acatctttat aataattgag
      301 tttttcaata aattcgtcaa aatcatcaac ctcaaaataa agttccatat tatttgattt
      361 ttgtataact gtatctggat taatccctgt aagccatgcg aagtcttctt gtatagcaaa
      421 tcctccttta aatgttacat ttttacctaa gtccaattca atttcttgct caaataattc
      481 tttgtaaaat ttttttgata cttcaatatc cttcactgct aataatgaaa cctgatattt
      541 cataaatttt cctcctaatt ttttatttct attttttcag tatcttctat taacattttt
      601 ttctctatct cttcagtacc ttttattaat cctttatttt tactttttta gtatcttcta
      661 ttaacacttt tgtttctacc tcttcagtat cttatatcaa tcttttattt tttcaatatc
      721 ttctattaac acttttatct ctatctattc agtactttct atcaatcttt tgtttttatt
      781 ttttcaatat cttctattaa tacttttgtt tctacctctt cagtatctta tatcaatctt
      841 ttattttttc aatatcttct gttaacactt ttatctctat ctctttaata tcttatatta
      901 atcctttatt tttatttttt caatatcatc attaattcct atttatttta tcatcttaaa
      961 tacgaaaaca ctgtgtcata tttgcaaaat atatattatc atctatatta aagcttcaca
     1021 atttatattt aaaaattctc tttaattaca ctacctctat ttaaaaagct accttaatta
     1081 tacttataag taaaggtagc tttttaaatt taattaaata gaatatccac tattaattta
     1141 tatttaattt atttagattc acattatagt atcataatcc acttataatc atttgtcata
     1201 ttacttaagt agactaatat attacataaa tacacttaca tacactttat attgatgcta
     1261 taagaaatac gtttgcttat acgtctttct cctcttcttt tagatttttt atccactctt
     1321 caataagtaa aatatcatct ttgctcaaat taatattttc atgtaatgac aacaataaac
     1381 tttttataga agaatcatga atatttctaa aaaaatctct tgtctcaact cctatgtatt
     1441 ccttttcttt aattaaaact tcataatgcg tatatttatc tatcttttga gaatttagaa
     1501 atctttttac tactaatcta gataaaagag tcaaagttgt cgtttgtttc cattgatatt
     1561 tttgctccat tcctaaaaca atatctctag atgttacttt ggaatctgat ttccatataa
     1621 atttcattat ctttaattct gattgtggca acttttttat agtcatgata aaaccttgct
     1681 actcagaata tagacaagca atatccataa taaaattttt cgattaaata catcttatac
     1741 ggatttatat aagctcagac ttataagata tttttcaatc ttaatcctaa atttagctat
     1801 ttgtacacgg taaatatata taaataatgt caaaattctc ttgtattata ttgcttaatt
     1861 ttatgaaata ttttgtactc agctatctat tttggatact tgtccagtag ctctcctttc
     1921 ttttaaactc tttgatttta aatatttgta tttcagtaaa tcctacttcc taaatttttt
     1981 atttactaca acttattact gaacttccta cttcctaaac tttttattta ctacaactta
     2041 ttactgaact tctcacttac taaatttctt acttactata aattataact aaacttctca
     2101 cttactaaat ttcttactta ctataaatta ctactaaact tcctactttc taaatttctt
     2161 acttgctaca aattattact aaacttccta ctccctaaat ttcttacttg ctataaatta
     2221 ttactaaact tcctactttc taaatttctt acttactata aattattact aaacttccta
     2281 ctccctaatt ttcttactta ctataaatta ttactaaatt tcctactttc taaatttctt
     2341 acttactaca aattattact aaacttccta ctccctaaat ttcttacttg ctataaatta
     2401 ttactaaact tcctactccc taagtttctt acttgctaca aattattact aaacttccta
     2461 cttcctaaat ttcttacttg ctataaatta ttactactaa acttcccact tactaaattt
     2521 cttacttact actacttata actaaacttc ccacttccta aatttcttac
//
LOCUS       DAFAZV010000136         2562 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFAZV010000136 DAFAZV010000000
VERSION     DAFAZV010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2562
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.140"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            168..569
                     /gene="tnpA"
                     /locus_tag="KOU88_004099"
     CDS             168..569
                     /gene="tnpA"
                     /locus_tag="KOU88_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBK3213906.1"
                     /translation="MYKSNENIVYDCKYHIVFCPKYRKPVLVGEVEKMLKEILPYKAD
                     ELGAEIIEMETDKEHVHLLISCDPQYGIHKVVKGLKGFSSRVLRENFPHLKSSMPSMW
                     TNSYFVGTVGSVSLEVVKQYIDNQPIRSKKK"
     gene            566..1729
                     /locus_tag="KOU88_004100"
     CDS             566..1729
                     /locus_tag="KOU88_004100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003435058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK3213907.1"
                     /translation="MIKTHRVKLNLTRTQFELIREKQMESANCWNHIVNLSKEYYFEH
                     KQWIKKNDIQKSIKGKYNLHSQTIQAISDKFDANRKTISELRKKGNTKAKYPYKTKKF
                     YIIPFKASAINRNAKGNLKLSMSKGRYLELDFNVENIKTAEIVWRNGYYLYYTFDNEL
                     NGVVAKGTNTVGVDLGEIHSIASVTNEGVGLILSNREGRSIKQFRNKMYAYISKRLSK
                     CKKGSRQSKKLWRLKNKIRSKTDNQLMNLYHQTTRKFIDFCVEQKVCEIVLGDIKGVE
                     KDTKKKKRLNRVNRQKISQMEYGRIKDYIKYKAKEQGIEVKLVKENYTSQTCPKCSKK
                     HKPTGRTYSCTCGYKTHRDIVGAWNILNKKHKYGLVDFRINHKQPINLKVSTV"
     gene            2016..>2562
                     /locus_tag="KOU88_004101"
     CDS             2016..>2562
                     /locus_tag="KOU88_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HBK3213908.1"
                     /translation="MTWNDLKNNDITYIVEYINSKLNDSKSLTKVAIELGVSESSIRK
                     YLTKRGYKRINDEYVFIGDNSMTKVVNNRQQSNNDNRFNMTIEDDNNHNIVIDNQFKN
                     NIISLAKDYDKIQDVLNWFENKEDTNVIEIVQDGIKIDLPSKDAIRTTVRLNKDAWNL
                     FDEFCEKFREFNKSDLMSMALL"
BASE COUNT         1074 a          271 c          463 g          754 t
ORIGIN      
        1 gtagtaagta tataaagtca atatactaaa ttacaataaa attgccaaaa agccctctcc
       61 tttaggtgta gggatgaaag gtaaggtctt aatataaaaa aagttagaat aatgcttgta
      121 atctaatacc actactgata ccctatattt aggaggtgtt agtttttatg tataaatcta
      181 acgaaaatat agtttatgat tgcaaatatc atattgtatt ttgccctaag tatcgtaaac
      241 ctgttttagt tggcgaagtt gaaaagatgt taaaagaaat actaccatat aaagcagatg
      301 aacttggagc agaaataata gaaatggaaa ctgataaaga acatgtgcac ttattaatat
      361 cttgtgaccc tcaatatgga attcataaag tagtaaaagg tttaaaaggc tttagttcga
      421 gagtattaag agagaacttt ccacatttaa agtctagtat gcctagcatg tggactaata
      481 gttatttcgt aggaactgtt ggctctgtaa gtttagaagt agttaaacaa tacatagaca
      541 atcaaccaat taggagtaag aaaaaatgat aaaaactcat agagtaaaat taaacctaac
      601 tagaacacaa tttgaattaa taagggaaaa acaaatggag agtgctaatt gttggaatca
      661 tatagttaac ttatctaaag aatactattt tgaacataaa caatggatta aaaagaatga
      721 tatacaaaag tcaatcaaag gtaagtacaa tcttcatagt caaactattc aagctatatc
      781 agataaattt gatgcaaata gaaagactat atcagaatta agaaaaaaag gtaatactaa
      841 agcaaaatat ccatacaaga ctaagaaatt ttatataata ccttttaaag ctagtgctat
      901 taatagaaat gctaaaggca acttaaaatt atcaatgtca aaaggcaggt atttagaatt
      961 agattttaat gttgagaata taaaaactgc tgaaatagta tggcgaaacg gatattattt
     1021 atactacact tttgacaatg aattaaatgg agttgtagcc aaaggcacca ataccgtagg
     1081 tgtagactta ggggaaatac attcgatagc tagtgtaaca aatgaaggtg tagggcttat
     1141 tctatctaat agagaaggca gaagtattaa acaatttaga aataagatgt atgcttatat
     1201 atctaaaaga ttaagtaaat gtaaaaaagg tagtagacaa tcaaagaagt tatggagatt
     1261 aaaaaataag ataagaagta aaacagataa tcagttaatg aatttatatc atcaaacaac
     1321 tagaaagttt atagactttt gtgtggagca gaaggtatgt gaaatagttc ttggggatat
     1381 aaaaggggtt gaaaaagata ctaagaaaaa gaaaagatta aacagagtta atagacagaa
     1441 aatatctcaa atggagtatg gtcgaataaa ggactatata aaatataaag caaaagagca
     1501 aggtattgaa gttaagttag ttaaagaaaa ctacacttct caaacttgcc caaagtgttc
     1561 taaaaaacac aaaccaactg gtagaactta tagttgtact tgtggttata aaactcatag
     1621 agatatagtt ggtgcttgga atattttaaa taaaaagcat aaatatggtt tagtagattt
     1681 tagaataaat cataagcaac caataaattt aaaagtatct accgtttgag ccatgtgtgg
     1741 gcgaataact ttaaggtagt agtggcgaag acaccgtccg aagtagcttg gctttgtaac
     1801 acacctctgt tgtactgttt aagtataaat aagtgcgtta gccaccaaga atccccttgc
     1861 tttaactatg gggagtgtgt caattattaa tagacgtaat attgtaaaaa aatgatatag
     1921 tttagaaaga tatgtagatt aaacgtagaa ttaaaagatt aacatagtat gacaatcata
     1981 atctcgtgta gtatacttaa attagaggtg agtatatgac ttggaatgat ttaaaaaata
     2041 atgatataac atatatagtt gaatatatta atagtaagtt aaatgatagt aagagtttga
     2101 ctaaagttgc tatagagctt ggtgtatctg aaagtagtat aagaaaatat ctcactaaaa
     2161 gaggttataa acgtataaat gatgagtatg tgtttattgg tgacaatagt atgacaaagg
     2221 tagtaaacaa cagacaacag agtaataatg ataatagatt taatatgaca atagaagatg
     2281 acaacaatca caacatagta attgacaacc aatttaaaaa taatataatc tctttagcaa
     2341 aagactatga taaaatacaa gatgtattaa actggtttga gaataaagaa gatacaaatg
     2401 taatagaaat tgtacaggat ggtattaaaa ttgatttacc ttcaaaagat gctataagga
     2461 ctacagttag gttgaataaa gatgcatgga acttatttga tgagttttgt gaaaaattta
     2521 gagagtttaa taaatctgat ttgatgagca tggcattatt ag
//
LOCUS       DAFAZV010000137         2519 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFAZV010000137 DAFAZV010000000
VERSION     DAFAZV010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2519
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.141"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            64..1545
                     /locus_tag="KOU88_004102"
     CDS             64..1545
                     /locus_tag="KOU88_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional diguanylate
                     cyclase/phosphodiesterase"
                     /protein_id="HBK3213909.1"
                     /translation="MKKNRLIAKNISIAFIVLFFFSVFTFFYVGNINRVLEYETNDII
                     TVTIAGWIILSFLFLGIIIYILYSKANSQKTIEKVAYTDFVTGYSNWRKFELDVTNLL
                     KKTSQNNKYAMVIFDIDKFKAINDIYGHKKGNLILKDIADTLNELTNINETFARVSAD
                     NFNILLTYNKKEDIINIIKKIMANNELVNLSFGIYEIKDKDLSVSVYSDRASLAKSSI
                     KNNSDVNFAFFNDKLREKLLFEDKIEKEMEYALESGQFIMYLQPKYNIKLDKFCGSEA
                     LVRWQYTEKEVIYPGDFIPIFEKNGFIRKIDMYILEQACKEIRSLFDKGISPLPISVN
                     FSRVDFFKKDFIENIVNICDRYKIPYSLIEIEITESSMFGDTDTLFNVSRNLQDIGFI
                     VAMDDFGSGYSSVNMLKNIPLNVIKLDRGFFVDDKDVDKSQIVIKSIVSLIKQLGIRV
                     VAEGIETRSQIEMLKKANCDIVQGYYFSKPLPIKEFEKLVYKI"
     gene            1578..>2519
                     /locus_tag="KOU88_004103"
     CDS             1578..>2519
                     /locus_tag="KOU88_004103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cache domain-containing protein"
                     /protein_id="HBK3213910.1"
                     /translation="MIRAKSLKNVLSIVLIFLFTIISFSDFAFKTNVQEEENSKINLR
                     EISLQSSNAIKIKLDSSLSFIKSVANMVSYFNTIDNSKIVPLLANISKESDFQRISIV
                     SPDGISHTSDGKIINVSKYQYFKKAIKGESNISEVVKSPIDGKDTFVIATPVFNKNNK
                     IIGVLYGSYYNDKLAEFIDITSFNSEGYIDIFESSGQFVLKSSHTNKLIKSSSNIYDI
                     FKKASFDDGYSYKKIYEDTKNNKSGFTSYEYKGENRYATYTPIGVNDWYVISVIPQYT
                     VRRNIDKINQLAFSLIFKVFLLFIMLIIYIIYKNNKSQ"
BASE COUNT         1020 a          241 c          381 g          877 t
ORIGIN      
        1 ttaatagtaa aataaagtga atcaattata ttataattgc taaagagagt gaggtgtagc
       61 tatttgaaaa aaaatagatt aatagcaaag aatatatcaa tagcatttat agtactattc
      121 ttttttagtg tatttacatt cttttatgta ggtaatatta atagagtgtt agaatatgaa
      181 acaaatgaca taataacagt tacaattgct ggatggatta tactttcatt tttattttta
      241 ggtattataa tttacatatt atattcaaaa gcaaatagtc aaaaaactat agaaaaagta
      301 gcatatacgg attttgtaac aggttattcc aactggagaa agtttgaatt agatgttaca
      361 aatttattaa agaagacatc acaaaataat aaatatgcaa tggtcatatt cgatattgat
      421 aaatttaaag caattaatga tatatatggc cataaaaagg gaaatttaat attaaaagat
      481 attgcagata ctttaaatga attgactaat atcaatgaaa cttttgctcg tgtaagtgct
      541 gataatttca atatattatt aacatataac aaaaaagagg atataataaa tattatcaaa
      601 aagattatgg caaataatga acttgtaaac ttatcttttg gaatttatga aatcaaagat
      661 aaggatttat ctgtaagtgt atatagtgat agagcttcac ttgcaaaatc atcaataaaa
      721 aataatagtg atgtaaattt tgcatttttt aatgataaat taagagagaa attattattt
      781 gaagataaga tagaaaaaga aatggaatat gctcttgaaa gtgggcaatt cataatgtat
      841 ttacaaccaa aatacaatat taaattagat aaattttgtg gaagtgaagc cctagtcaga
      901 tggcaatata cagaaaaaga ggtcatatat ccaggtgatt ttattcctat atttgaaaaa
      961 aatggattta ttagaaagat tgatatgtac atattagaac aagcttgtaa agaaatccgg
     1021 tctttatttg ataaaggaat ttcaccttta cctatatctg taaacttctc aagagttgat
     1081 ttttttaaaa aagattttat tgaaaacata gtaaatatat gtgatagata taaaatacca
     1141 tatagtttaa tagaaattga aattactgaa tctagtatgt ttggagatac tgatactcta
     1201 tttaatgtta gtagaaatct acaggatatt ggctttatag ttgcaatgga tgattttggc
     1261 tcgggatatt cttctgtaaa tatgcttaaa aatataccat taaatgtaat aaaattagat
     1321 agaggatttt ttgttgatga taaagatgtt gataagagtc aaattgttat aaaaagcata
     1381 gtttctctca ttaagcaatt aggaataagg gttgttgctg aaggaattga aacaagaagt
     1441 caaatagaaa tgttaaaaaa agcaaattgt gatattgttc aaggatatta tttttcaaaa
     1501 ccattaccaa ttaaagaatt tgaaaaatta gtctataaaa tatagtcagc gagtcttaaa
     1561 tgggaggtgg tgattaagtg ataagagcaa aatcgttaaa aaatgtactg agtattgttt
     1621 taatattttt atttacaata atttcttttt ctgattttgc atttaaaact aatgtccagg
     1681 aagaagaaaa tagtaaaatt aatttaaggg aaatatccct acaaagttcc aatgctataa
     1741 aaataaaatt agatagttct ctatccttta ttaaaagtgt ggcaaatatg gtttcttatt
     1801 ttaatactat agataactca aaaatagttc cattattagc taatatatca aaagaatctg
     1861 actttcaaag aatctctatt gtatctcctg atggaataag tcataccagc gatggcaaaa
     1921 ttatcaatgt gtcaaagtat cagtatttta agaaagctat taaaggagaa agtaatatat
     1981 ctgaagttgt gaaatctcca attgatggaa aagatacttt tgttatagct actcctgtat
     2041 ttaataagaa taataaaata attggtgttt tatacggttc ttactacaat gataaattag
     2101 ctgaatttat agatataaca agttttaata gtgaagggta catagatata tttgaatcta
     2161 gtggtcaatt tgttttaaaa tcttcacata caaacaaact gattaagtca agtagtaaca
     2221 tatatgatat atttaaaaaa gcttcttttg atgatggtta tagctataaa aaaatatatg
     2281 aagatacaaa aaataacaag agtggtttta cgtcatatga atacaaagga gaaaatcgtt
     2341 atgctactta tacacccatt ggtgtaaatg actggtatgt aatttctgtg ataccacaat
     2401 atactgtaag aagaaacatt gataaaataa atcaattagc attttctctt attttcaagg
     2461 tattcttatt gtttattatg cttataatat atattattta taaaaacaat aaatctcag
//
LOCUS       DAFAZV010000138         2493 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFAZV010000138 DAFAZV010000000
VERSION     DAFAZV010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2493
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.142"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(239..367)
                     /locus_tag="KOU88_004104"
     CDS             complement(239..367)
                     /locus_tag="KOU88_004104"
                     /inference="COORDINATES: protein motif:HMM:NF016296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213911.1"
                     /translation="MEYIQFICKNTVVINGKDIPVSKYRMANLKKKLTYVLGDVLC"
     gene            complement(506..1216)
                     /locus_tag="KOU88_004105"
     CDS             complement(506..1216)
                     /locus_tag="KOU88_004105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018590547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213912.1"
                     /translation="MYRIVICEDDITQIAFLRECILKSLEGISSQIELFEFNSGEELL
                     ETNLEGIDIFFLDIKMLQLTGMDVAKIIRETNDTSEIIFITSIVDYIQEGYKVRAYRY
                     LLKPIDFGDLNESILSCISDIIKKRENFMLIENKGIINKILINSIMYIEVRKKVLTIH
                     TKNDTYYTKNSMDKIELELEKYNFFRCHKSYLINLEYIQFICKNTVVINDEDVPVSKY
                     RMADLKKKLTYVLGDVLC"
     gene            complement(2307..2477)
                     /locus_tag="KOU88_004106"
     CDS             complement(2307..2477)
                     /locus_tag="KOU88_004106"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213913.1"
                     /translation="MPPDTETKVTLVFTVTHTSSGKTADTGEIEVTVPARTTTVSSLL
                     GRIAVNIFNFNK"
BASE COUNT          966 a          344 c          197 g          986 t
ORIGIN      
        1 actacataat ttattttata caatacatat gtaataaata tacatataaa taatttaata
       61 tttatattaa actcaattgt attcaacata gtaattatca taatagcaat tactatgcta
      121 ctatttaggg ttaatctatt ctttcttaac tcactaaatt catttaataa aaattttaat
      181 acaatccatt ctatcgtcgt agaaaatata ggtaaaaaaa tccaaaatac atttatattt
      241 aacataatac atctcccaat acatatgtta attttttctt taaattagcc attctatatt
      301 tactaactgg tatatcttta ccattaataa ctacagtatt tttacatata aattgaatat
      361 actccaaatt aattaaatag ctcttgtaac atttttaaaa atttattctt tcttaaatca
      421 ctgaattcat ttgataaaaa ttttaataca attcattcta tcgccgtaga aaatataggt
      481 aaaaaaatcc aaaatacatt tatatctaac ataatacatc tcccaataca tatgttaatt
      541 ttttctttaa atcagccatt ctatatttac taactggtac atcttcatca ttaataacca
      601 cagtattttt acatataaat tgaatatact ccaaattaat taaatagctc ttatgacatc
      661 taaaaaaatt atatttttct agctctaatt ctattttatc catactattt ttagtataat
      721 aagtatcatt tttagtatgt atagtcaaaa cctttttcct aacctctata tacataatac
      781 tattaattaa aattttattg attatacctt tattttctat cagcataaaa ttttctcttt
      841 tttttataat atccgatata caactcaaaa tactttcatt taaatctcca aaatctatag
      901 gctttaataa atatctataa gcccttacct tatagccttc ctgtatgtaa tcaactattg
      961 aagttataaa tattatttca gaagtatcat tagtttctct aattatttta gccacatcca
     1021 tgcctgttag ttgaagcatt ttaatatcta aaaaaaatat atcaatacct tctaaatttg
     1081 tttccaataa ttcttctcct gaattaaact caaatagttc aatttgacta gaaataccct
     1141 ctaaggactt taatatacac tctcttaaaa aagctatttg tgtaatatca tcctcacaga
     1201 taactattct atacataaac acccctcctt agacattaga tctgaaaaca aataaaatat
     1261 caatttataa ataattattt agttatacaa ctaacatggt catcaaatac tattattcac
     1321 ttaaaaaatc accccctatt tttagtatgt taacaacaaa ataagaagat atcttagatt
     1381 tttaaaaaca attaatactt aatgtagttt tgtatactat ttataggtaa ttttttatat
     1441 cattttaaac attaaaatta ttgatgttta agaactatta tattgatagt aatatataat
     1501 taatgatatc aaaaattttt aattagactt ctctcttatt caagattttt ctatataaaa
     1561 tctaagaata aatagaaaac taacatctaa ccttttattt tttattttcg atctatttac
     1621 ttgaatttta acataaatct atcttttagt atatattaat catgctgaat ttgtgatgac
     1681 atgtatacaa aatatcgttt agtattttct aataaaaaat attactgaaa ttaaaaatct
     1741 acaatagcat ttaacaagta aaaacatgtt tacacaaata tataatttaa ggtctttaaa
     1801 atagagtatg tattattcta aaaattagtt atagttatca cataaaaata gaaaagaatt
     1861 ttcaaaagat ttaaagaaca tatatacttc aattgcagaa gatgtaatgt taagtgaact
     1921 agcattcttc gaggaaaaat agactcaaaa aattagaaaa tagaatcagg ttttagatga
     1981 tttaagtatt tattttcaaa aaagaaattt gattctaagt taataaagaa atatttaaaa
     2041 aaatcaaaaa attttcttaa ataagtaata ggttttgtaa aaatggaaaa atatcaaaat
     2101 aagactatga tttttaaaac tatagcctta tcaataaatt tttatttaaa gaacacacat
     2161 aaatattttt aaacctaatt tatgtgaagt tttatgtatt ttttatataa gtagtattct
     2221 aatcttactc atctaatata ccaaaaagac tgtaagtaag ttcactttta tgcaaactta
     2281 cccacaatct cttttacaca ttaattctat ttattaaaat taaaaatatt tactgctatt
     2341 ctacccaata aagatgatac tgttgttgtt ctggctggta ctgttacttc tatttctcct
     2401 gtatctgctg ttttaccact tgatgtgtgt gtcactgtaa atactaatgt tacttttgtt
     2461 tctgtatctg gtggcactat tgttccatct ttc
//
LOCUS       DAFAZV010000139         2373 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFAZV010000139 DAFAZV010000000
VERSION     DAFAZV010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2373
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.143"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..322)
                     /locus_tag="KOU88_004107"
     CDS             complement(<1..322)
                     /locus_tag="KOU88_004107"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213914.1"
                     /translation="MLISEYIKDNRCGKKSKLYFKKLEEIKQEFINRDLEYLLLTTWD
                     EEISCMMKTGRDLDKLKYRDGFKEINNLFDSISEEIRDEYKEKDTYTMFFSSCSKEKY
                     YIACE"
     gene            complement(423..1466)
                     /locus_tag="KOU88_004108"
     CDS             complement(423..1466)
                     /locus_tag="KOU88_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBK3213915.1"
                     /translation="MEIINRENEKRIISFNNELFGEIRTIRIENEPYFVATDIAKALG
                     YKDTTNAIKQHCRWVVKHHIPHPQSKTKTLEVNIIPEGDMYRLIINSELPSAEKFERW
                     VFDEVLPSIREHGAYMTNEALEKAINDPDWTIKLLTELKKERATKEKLKVEQEKNKPK
                     LELANAIESSSSSILIAQLSKILNQNGVDIGQNRLFEWMRNNEYLIRKKRADHNTPTQ
                     KSMDLKVLEVSESTGIDKDGNTVIRQTPVVTGKGQIYFVNKILKENNKVLKRFMINND
                     YIRGVMVEIGKTYAIYDHEYYGFIGILKSVRNEKIRVEKIGDVSSSRDIPICMIDYIE
                     EASKEDINKYLSK"
     gene            1727..2176
                     /locus_tag="KOU88_004109"
     CDS             1727..2176
                     /locus_tag="KOU88_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213916.1"
                     /translation="MFGERLKKLRIKFGLKQHELAEILNVSQSTIGMYENDQRTPPAE
                     SIVKLAEYFNVTTDYLLGHTKTNYSVSANIPGMPSIVCEDNSIYDILDGKKDIKSLED
                     MNKFLENTDYNNEVKEVLKKYMQLDEMDRKAIERMIDNAYERLKEDN"
BASE COUNT          770 a          407 c          255 g          941 t
ORIGIN      
        1 actcacaagc tatataatat ttttctttag agcaactgct aaaaaacatt gtatatgtat
       61 ctttttcttt atattcatct cttatttctt ctgatatgct atcaaataaa ttgtttattt
      121 ccttaaatcc atccctatat tttaacttat ccaaatctct tccagttttc atcatacatg
      181 agatttcttc gtcccaagtt gttaacaaca aatattctaa atctctatta ataaattctt
      241 gttttatttc ttcaagcttt ttgaaatata atttactttt tttcccacat ctattatctt
      301 taatatattc acttattaac ataacattat ctcctttatt ctgatacatt aattgtatca
      361 attctaaagg aaaatttata ctacaaaagg aaatagaagc caaaactcct atttccacaa
      421 aatcatttac tcaaatattt attaatatct tctttactag cttcttctat gtaatctatc
      481 atacagattg gaatatccct actgctagaa acatctccta ttttttctac tcttattttc
      541 tcatttctta cactctttaa tataccaata aatccatagt actcatggtc atatatagca
      601 tatgttttac ctatctcaac cataactcct cttatgtaat cattatttat catgaatctc
      661 ttaagtactt tgttattctc tttcaatatc ttatttacaa aatatatttg tccttttcca
      721 gttacaacag gagtttgtct tattacagta tttccatctt tatctatccc agtactctca
      781 gaaacctcta atactttcaa atccattgac ttttgagttg gagtattatg gtcagctctt
      841 ttcttcctaa ttagatattc attatttctc atccactcaa acaatctatt ctgccctata
      901 tctactccat tctgatttaa tatcttagat agttgagcaa ttagtattga gcttgatgaa
      961 ctttctatag cattagctag ttcaagttta ggtttatttt tctcttgctc tacttttaac
     1021 ttttctttag tagctctctc tttctttagt tctgtaagta attttatagt ccaatctggg
     1081 tcattgattg ccttctctaa tgcttcatta gtcatataag ctccatgttc tcttattgat
     1141 ggaagaactt catcaaatac ccaacgctca aatttttcag cacttggtaa ttcgctattt
     1201 ataattaatc tatacatatc accttctggt attatattca cttccaaagt tttagtttta
     1261 ctttgtgggt gaggtatgtg gtgtttcacc acccacctac aatgttgttt aattgcattt
     1321 gttgtgtcct tatacccaag agcttttgca atatctgttg cgacaaaata gggttcattt
     1381 tcaattctaa ttgttcttat ttctccaaat aattcattgt taaagcttat tattcttttt
     1441 tcattttctc tattaattat ctccataatt aatccctcct tataagttgt attttttata
     1501 agaagctgat ataatcattc tattcaagtt gataattata tcagctattt aagaagtctt
     1561 actcgccgtc caaagtttgt aaggcttctt tttaattact aaaagtaatt ttatcactta
     1621 aagtaattta tatttttata atatactcca cataatgtaa tgtcaagtat aatattttat
     1681 tactttatgt ggtataataa ttataaagat atcttggagg tgaaaaatgt ttggagaaag
     1741 attaaaaaaa cttagaatta agtttggatt aaagcaacat gaattagctg aaatattaaa
     1801 tgtatcacaa agcactatag gtatgtatga aaacgaccaa agaactccac cagcagagtc
     1861 tatagttaaa ctagctgaat actttaatgt cactacagat tatcttttag gtcatacaaa
     1921 aaccaactat tcagtcagtg caaatatacc tggtatgcca tcaatcgtat gtgaagataa
     1981 ttccatctat gatatacttg atgggaaaaa agacattaaa tctttagaag atatgaataa
     2041 attcttagaa aatactgatt acaataatga agtcaaagaa gttcttaaaa aatatatgca
     2101 actagatgaa atggatagaa aagctataga gagaatgata gataatgcat atgaacgact
     2161 aaaagaggat aattaatata cacctctttt ttaaattata cttgtcatac ctctgtcatc
     2221 attgaattat aacaaaaaaa gcctacttta agtagacctt ctaattgttc attaataagc
     2281 taaacttgta accacagtgt cttttgttgt cttacatata tcttctatag atttactttc
     2341 tagctcaatt ataccataca aatcatatac aaa
//
LOCUS       DAFAZV010000140         2343 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFAZV010000140 DAFAZV010000000
VERSION     DAFAZV010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2343
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.144"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..324
                     /locus_tag="KOU88_004110"
     CDS             <1..324
                     /locus_tag="KOU88_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213917.1"
                     /translation="LELKAGLMETEFRLGFAKLVRIICKHIGYSPKRVLQTWTRNMIQ
                     NDLELADICSKSVGIVSEKTNLKNHPLVDNAEEEEKQIKKEKEYNQQEYNSIIPNNSG
                     VINET"
     gene            314..1801
                     /locus_tag="KOU88_004111"
     CDS             314..1801
                     /locus_tag="KOU88_004111"
                     /inference="COORDINATES: protein motif:HMM:NF015461.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBK3213918.1"
                     /translation="MKHKDYWRKRFEQLEEAQNNKSIKCYLELEKQYKLAMTSIEKDI
                     LAWYNRFAESEGISLLEAKKLLNTRELEEFKWNVEEYIKYGKENAINQKWIKELENAS
                     ARVHITRLEALKLQIQQQVEVLYGNEIDGIDKLMRDIYTSGYYHTAFNVQQGVNVGWS
                     LMSLDTNRINKVISKPWATDGLNFSERIWGKHRPALINELYTKLTQSIIRGENPKNLV
                     NDFAKRFNVSKSQAKNLIMTESAFFASASRKDCFNDLDVEKYEIIATLDLRTSNICRE
                     LDGKVFDMKDYQVGVTAPPFHCRCRTTTAPFFSDEEGYRAARGEDGKTYYVPSSMKYK
                     EWYEKYINKNIKLSDNEQLAINKYVSSDSYKINEKLRRGLSLTSEDKNFISNLDSALD
                     KMPNYKGNVNRSLYFFNEKEKIDFLNKHQIGKEIVYNEYISTSSRGEYNPSGQVELNI
                     ISTNGKDIRKYNPQEAEILFKRNSKFITTDNFEYDGKHYITMKEV"
     gene            1803..1961
                     /locus_tag="KOU88_004112"
     CDS             1803..1961
                     /locus_tag="KOU88_004112"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213919.1"
                     /translation="MKKDNEKLFSAPRWTEIPQAKVVGERTLTEEEVKEAQEIRKKII
                     KRKINNKG"
     gene            2032..2277
                     /locus_tag="KOU88_004113"
     CDS             2032..2277
                     /locus_tag="KOU88_004113"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213920.1"
                     /translation="MIKLYILSIIVFCTGLYLFKMKIDSNEELIKILKNKKVRRKCNF
                     IFMALFPLLNFILGVIFIISSLLVSNEDIIKNLKGDK"
BASE COUNT         1003 a          217 c          430 g          693 t
ORIGIN      
        1 ttagaattaa aagcaggttt gatggaaaca gagtttagac taggatttgc taaactagta
       61 agaataatat gtaagcatat aggatattcg cctaaaagag ttttacaaac ttggactagg
      121 aatatgattc aaaatgattt agaactggct gatatatgct ctaagagtgt agggatagta
      181 tcagaaaaga ctaatttaaa aaatcatcct cttgtagata atgcagaaga agaagaaaaa
      241 caaattaaaa aagaaaagga atacaatcaa caagaataca atagtatcat tcctaataat
      301 agtggtgtta taaatgaaac ataaagacta ttggaggaaa agatttgaac aattagaaga
      361 agctcaaaat aacaaaagta taaaatgcta tcttgaatta gaaaagcaat ataaattagc
      421 tatgactagt atagaaaaag atatattagc atggtacaac agatttgctg aaagtgaagg
      481 aatatcttta ttagaagcta agaaactact aaatacaaga gaactagaag agtttaagtg
      541 gaatgtagaa gaatatatta aatatggtaa agaaaatgct ataaatcaaa agtggataaa
      601 agaattagaa aatgctagtg ctagagttca tattacaagg cttgaagctt taaagttaca
      661 aatacagcaa caagtagaag ttttatatgg aaatgaaatt gatggtattg ataaactaat
      721 gagagatatt tatacaagtg gatattatca tacagctttt aatgttcaac aaggagtaaa
      781 cgttggttgg agtttaatga gtcttgatac taacagaata aataaagtta tctctaaacc
      841 atgggcaaca gatggattaa actttagtga aagaatttgg ggtaaacata gacctgcttt
      901 aatcaatgag ctatatacta aactgacaca atcaattatt aggggtgaga atccaaagaa
      961 cctagtaaat gactttgcta agagatttaa tgtgtctaaa tctcaagcta agaatttaat
     1021 aatgactgaa tcagctttct ttgcatcagc aagtagaaaa gattgtttca atgatttaga
     1081 tgtagagaaa tatgagatta ttgctacatt agatttaaga acttcaaata tatgtagaga
     1141 gctagatgga aaagtatttg atatgaaaga ttatcaagtt ggagttacag ctccaccatt
     1201 tcattgtcgt tgtaggacaa caacagctcc tttttttagt gatgaagaag gctatagagc
     1261 agcaagagga gaagatggaa aaacatatta tgtaccatct agtatgaagt ataaagaatg
     1321 gtatgagaaa tatattaata aaaacattaa gttatcagat aatgaacaac ttgcaattaa
     1381 taaatatgta agtagtgatt cttataaaat taatgagaaa cttagaagag ggttatcatt
     1441 aacaagtgaa gataaaaatt ttataagtaa cttagatagt gcattagata agatgcctaa
     1501 ttataaggga aatgtgaata ggtccttgta tttctttaat gaaaaagaaa aaatagactt
     1561 tttaaataaa catcaaatag gtaaggaaat agtatataat gaatatatat ctacatccag
     1621 tagaggggaa tacaatccaa gcggtcaagt tgaattaaat attataagca caaatggcaa
     1681 ggatataaga aaatataatc ctcaagaagc agagatttta tttaaaagga atagtaaatt
     1741 tataactact gataattttg aatatgatgg caaacattat ataacaatga aagaggtgta
     1801 atatgaaaaa ggataatgaa aaattatttt cagcaccaag atggacagaa ataccacaag
     1861 ctaaagtggt aggggaaaga acattaacag aagaagaagt gaaagaagcg caagaaatta
     1921 gaaaaaaaat aattaaaaga aagattaata ataaaggata gaagcacttg ctaaatgata
     1981 aattagtagg tgcttttatt atgtaaaaat ttattgagag ggtgatttga aatgattaaa
     2041 ttatatattt tatcaataat tgtattttgt acagggcttt atttatttaa aatgaagatt
     2101 gatagtaatg aggaattgat taagattctt aaaaataaaa aagtaagaag aaagtgtaat
     2161 tttattttta tggctttatt tccactactt aattttattt taggtgtgat atttatcata
     2221 tcttctttac tagttagcaa tgaagatata attaaaaatt taaaggggga taagtaatat
     2281 ggctaaattt gtgaagaaac cagttgaagt agaagctttt aaactaggtt atgatgtaga
     2341 acc
//
LOCUS       DAFAZV010000141         2197 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFAZV010000141 DAFAZV010000000
VERSION     DAFAZV010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 2197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2197
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.145"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..370
                     /locus_tag="KOU88_004114"
     CDS             <1..370
                     /locus_tag="KOU88_004114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK3213921.1"
                     /translation="EKCLKPYKLTNGLYFYLIYINKNRNCSLNDVSTEFEVDKAHTTR
                     TISRLEQDGYIEKIQNPNDSRAFQLRVTDKGEEVLGDIKNIFSKWDNHIKKEFSDTEY
                     KELVKNLHVVKDIKTAVEEE"
     gene            372..1466
                     /locus_tag="KOU88_004115"
     CDS             372..1466
                     /locus_tag="KOU88_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavin oxidoreductase"
                     /protein_id="HBK3213922.1"
                     /translation="MYCNLLKPIKIGNLELKNRVSFAPTSMGLKLEEKIKKFSDIAKS
                     GVALITLGDVSIRPSFHKVAISLSDEDGVMKYKKIVDEIHNSGAKVSAQLFCSDYDVN
                     LIKDTMKMGITSHDEIKKIMNDGVKDYITNMPKEEIKNIINLFKVTALNAKKAGFDMI
                     QIHGDRLVGSFSSSIFNNRNDEYGGTCDNRSRFASEIISSIRDEVKDIPIDYKFAIRQ
                     ENPHYGNAGVLFSEVEYFVKKFESLGVNSFHVTLANHSKLEDTIPTNNHPYFKDEGCF
                     LYLADEVKKHTNLPVCGVGKLSSPDFIESIISNNRVDMVSMSRQLLADSNWLQKVKDG
                     RVDEIKKCCYCNKKCADALQTRSQFGCILD"
     gene            1554..2084
                     /locus_tag="KOU88_004116"
     CDS             1554..2084
                     /locus_tag="KOU88_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HBK3213923.1"
                     /translation="MKSLVLYSSLTGNTKKIAYTIYDEIQEEKDIKDVNELVDYSIDY
                     ENYDIVFLGYWVDKGICDKNSKQVLENIHNKKIALFGTMGASKKGSYGASIIEKIESI
                     IPKDNEILGSFICQGKIAEGLKAKYKEMLKLSPDNEHIRQQLNNHEESQSHPDEQEIY
                     EASMFAKNMMIKASIV"
BASE COUNT          913 a          219 c          399 g          666 t
ORIGIN      
        1 tgaaaaatgt ttaaaaccat ataaacttac gaatggtcta tatttctatt taatttatat
       61 taataaaaat aggaattgtt ctttgaatga tgtttctaca gaatttgaag ttgataaagc
      121 tcatacaaca agaactatat ctaggttaga acaagatgga tacatagaaa aaatccaaaa
      181 ccctaatgat agtagagctt ttcagttgag agtaacagat aagggtgagg aagtattagg
      241 ggatataaaa aacatatttt caaagtggga taatcacata aaaaaagagt tctcggatac
      301 agaatataaa gaactggtaa agaatttaca tgtggtaaag gatataaaaa cagctgtgga
      361 ggaagaatag gatgtattgt aatttattaa aaccaattaa aattggaaat ttggaattaa
      421 aaaatagagt atcttttgca cctacaagca tgggtcttaa attggaagaa aaaattaaaa
      481 agttttctga tattgctaag tcaggagtag ctctgattac tctaggagat gtatctatta
      541 gacctagttt tcataaggta gctataagcc tatcggatga agatggagtc atgaaataca
      601 agaaaattgt agatgaaata cacaattctg gtgcaaaggt atcagcacaa ctattttgtt
      661 cagattatga tgttaattta attaaagata ctatgaagat gggaattact tcacatgatg
      721 agataaaaaa aataatgaat gacggagtaa aagattacat aacaaatatg cccaaagaag
      781 aaattaaaaa tattataaat ttatttaaag taacagcatt gaatgcaaaa aaagcaggtt
      841 ttgacatgat tcaaattcat ggtgataggc ttgtaggaag tttttcatca agtatattta
      901 ataatagaaa tgatgaatat ggtggaacgt gtgataatag aagtagattt gcaagcgaaa
      961 taattagtag tatccgagat gaagttaagg acattccaat agactataaa tttgcaataa
     1021 gacaagaaaa tcctcattat ggaaatgcag gagttttatt ttcggaagtt gagtattttg
     1081 ttaaaaaatt tgaatcccta ggtgtaaaca gttttcatgt aacacttgca aatcattcaa
     1141 aattagaaga tactatacca accaataatc atccttactt taaagatgaa ggctgttttt
     1201 tatatttagc tgatgaggta aagaaacaca caaatcttcc agtatgtggg gttggaaaat
     1261 tgtctagccc agattttata gaaagtatta tttcaaataa tagagtagat atggtttcta
     1321 tgtcaagaca attactagca gatagtaatt ggttacagaa agtaaaagat ggaagagtag
     1381 atgagattaa aaagtgctgt tattgtaata agaagtgtgc agatgcttta caaacacgct
     1441 ctcagtttgg atgtatacta gattagaata tccttataaa aataaataat ttgttaaggt
     1501 taatatattt ttggtgattt agataagtat ttagataaag aggaggagac atcatgaaaa
     1561 gtttagtttt atattcaagt ttaactggaa atactaaaaa gattgcttat actatatatg
     1621 atgaaattca agaagaaaaa gacattaaag atgtaaatga attagttgat tatagtattg
     1681 actatgaaaa ttatgatata gtattcttag gctattgggt ggacaaggga atttgtgata
     1741 aaaattcaaa acaagtgctt gaaaatattc acaataaaaa gatagcacta tttggaacaa
     1801 tgggagcaag taaaaaagga agttatggag ctagtataat agaaaagata gaatcaatta
     1861 tcccaaaaga taatgaaata ttaggttcat tcatatgtca aggtaagata gcagaaggat
     1921 tgaaagcaaa atataaagag atgttaaaac tttctcctga caacgaacat attcgccaac
     1981 aattaaataa ccatgaggaa tctcaaagtc atccagatga acaagaaata tatgaagcca
     2041 gtatgtttgc aaaaaatatg atgattaaag ctagtattgt gtagtagtta aacaataagt
     2101 tcatataaga tatagaataa ataatttagt aaaaaagtat agcaaataat ttgctatgct
     2161 ttttttatga aatcaaaaaa ataataaaaa tacttga
//
LOCUS       DAFAZV010000142         1988 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFAZV010000142 DAFAZV010000000
VERSION     DAFAZV010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1988
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.148"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            173..>1988
                     /locus_tag="KOU88_004117"
     CDS             173..>1988
                     /locus_tag="KOU88_004117"
                     /inference="COORDINATES: protein
                     motif:HMM:NF014826.1,HMM:NF019353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBK3213924.1"
                     /translation="MNKIQKEILTNNYVVYHLHDDTSNCNGFADSCSKYDEYISLAKE
                     NNMKAIAFSNHGGIYDWVKKKQACDNAEIKYIHGVELYTCINLEDNNRGWHIGLYAKN
                     LKGVRELNSLTSKATSKGILKDNSDRHFYFNPRISFDELMNTSDNIIITSACLASPLW
                     KLGDTNIIDIEGIEKYNYNIKKRQELLEWMSKNNHRCFLEIQYHNCDSQKEYNKMLYE
                     WSILYGIPLIAGTDTHSSSEYKAECRKVLQKSKNSFYGEEDEFDLTWKNYDDLVDEFK
                     KQNILPIDIILEAINNTNKLAAMVEDFTLDKTFKYPDLYGENSNQTWKDYIDEKLLKL
                     INVNAIEKEKIDIYKLRVQEEYEIMCNQGMASFMLFVAELVNWCKDNDIHVSPCRGSV
                     GGSLIAYITGITDVDAIRWKTAFSRFCNADRISLGDIDLDFSPSDRQKVYEYIVNRFG
                     KDKVSYILTFQTIKDRGSIDVLAKGLNYDNLNLVKNIKDTFDNIFKEYSKIIIEEINI
                     EELEGKESKSPDFIDHELYLHTIRNNKKKQRLIKLKEMWDELREHNKDLFYYFDGIRG
                     VITSKGTHPAGMIGSPITLYDNLGVFYKDGNENSPVSFC"
BASE COUNT          836 a          190 c          339 g          623 t
ORIGIN      
        1 attttattta aaaaagattt ttgtagtaaa aaatttttta acaaaatgat taacgaagat
       61 aataataacc ttaaatctaa ggatttaata atgaatatat tattttctat taaaaacaat
      121 gaaaatggat attcttatat agatataata gatgttgaaa gtagtgttgt aaatgaataa
      181 aatacaaaaa gaaatattaa caaataatta tgttgtatac cacttacatg atgatacttc
      241 taattgtaat ggttttgctg actcatgtag caaatatgat gaatatatat cattagcaaa
      301 agaaaataac atgaaagcaa tagcatttag taatcatggt ggtatttatg actgggtaaa
      361 aaagaaacag gcgtgtgata acgcagaaat aaagtatatt catggtgtag aactatatac
      421 atgcataaat ttagaagata ataatagagg ttggcatatt ggcttatatg caaaaaattt
      481 aaaaggtgtt agagagttaa attctctaac gtcaaaagct acatctaaag gaattttaaa
      541 agataatagt gaccgtcatt tttatttcaa tccaagaata tcctttgatg aattaatgaa
      601 tacaagcgat aatataataa taacttctgc ttgtctagcg tcgccattat ggaagctagg
      661 tgatacaaat ataatagata ttgagggtat tgagaaatat aattataata ttaaaaaaag
      721 acaagagtta ctagaatgga tgtctaaaaa taatcataga tgttttttag aaatacaata
      781 tcacaactgc gatagtcaaa aagagtataa taagatgctc tatgagtgga gtatcttata
      841 tggaatacca ttgatagcag ggacagatac tcattcatca tctgaatata aagcagaatg
      901 tagaaaagtg cttcaaaaat ctaaaaatag cttctatgga gaagaagatg aatttgactt
      961 aacatggaaa aattatgatg atttagttga tgagtttaaa aaacaaaata ttctacctat
     1021 tgatattata ttggaagcaa ttaataatac aaataaatta gctgctatgg ttgaagattt
     1081 tacactagat aaaactttta aatatcctga tttatatggg gaaaattcca atcaaacatg
     1141 gaaagattac atagatgaaa aacttttaaa attaataaat gtaaatgcta ttgaaaaaga
     1201 aaaaatagat atatataaac taagagtaca agaagaatat gaaataatgt gtaatcaagg
     1261 catggctagt ttcatgctgt ttgtagctga attagtaaat tggtgcaaag ataatgatat
     1321 tcatgttagc ccatgtagag gttctgttgg tggttcttta atagcataca taacaggaat
     1381 aacagatgtg gatgctatta gatggaaaac tgcattttca aggttctgca atgctgatag
     1441 aatatcactt ggagatatag atttagattt tagtccatca gatagacaaa aggtttatga
     1501 atatatagtt aatagatttg gaaaagataa agtatcatat atactaacat ttcaaactat
     1561 aaaggataga ggcagtatag atgtacttgc taaaggatta aattatgata atttgaattt
     1621 ggttaaaaat ataaaagaca catttgataa tatctttaaa gaatattcca aaataattat
     1681 agaagaaata aacatagaag agctggaagg caaagaaagt aaatcgccag actttataga
     1741 ccatgaatta tatttgcata caataagaaa caataagaaa aaacaaagat taattaaatt
     1801 aaaagaaatg tgggatgagt taagagaaca taataaggat ttgttttatt attttgatgg
     1861 gattagagga gtaataactt ctaaaggtac acatccagca gggatgattg gtagcccaat
     1921 aactttgtat gataatttgg gtgtatttta taaagatgga aatgaaaaca gtccagtatc
     1981 attttgca
//
LOCUS       DAFAZV010000143         1934 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFAZV010000143 DAFAZV010000000
VERSION     DAFAZV010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1934
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.151"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..342
                     /locus_tag="KOU88_004118"
     CDS             <1..342
                     /locus_tag="KOU88_004118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213925.1"
                     /translation="KTIDIEDMFELNLRAIRKRNEKIKNEIEKQIKYEDSEIKTTNRG
                     GPGKIIKIFNINTGEVKILKSAEEASRYIKVSRSYASYLARENKSTEDGWKAEYIQGA
                     TDGISKCGTSN"
     gene            311..451
                     /locus_tag="KOU88_004119"
     CDS             311..451
                     /locus_tag="KOU88_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213926.1"
                     /translation="MVLANVEQVIKLAEKILNKKKCSVNKAIDIAIKILSRYECEGML
                     EK"
     gene            567..743
                     /locus_tag="KOU88_004120"
     CDS             567..743
                     /locus_tag="KOU88_004120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213927.1"
                     /translation="MDDRLEIINASVNYIQMICESSNIAIIAERGRVRILDLETKEKY
                     DLLKNKLEEMLEEI"
     gene            857..1546
                     /locus_tag="KOU88_004121"
     CDS             857..1546
                     /locus_tag="KOU88_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213928.1"
                     /translation="MDLNKIMNDALVELEENGFVEEVVKKQLAETIKRVVNEVFGNWG
                     DFSKKIEKHLSENININLDKLDIQKYNVLVATTVKEKIDMTMKVEAIEHLKRNLDNML
                     VGAEKEYKMSELLEILKMDKYDIDEYEGYEDCITFILDENKYGSGWIEIDKEPNKSKY
                     RCEHSILLRKDGTIASYRYENREISSKDIMSGFDNFGDLLFKIFAHGSKIILDLGNDI
                     EDYDLTNGEDY"
     gene            1564..1785
                     /locus_tag="KOU88_004122"
     CDS             1564..1785
                     /locus_tag="KOU88_004122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213929.1"
                     /translation="MSKYVLRWQKGLLLDERKINYSCGSIENLKKKAELLAKDDKILL
                     VTIDKVEEVIKDTRSQKMAEYFEDEGVEV"
     gene            1782..>1934
                     /locus_tag="KOU88_004123"
     CDS             1782..>1934
                     /locus_tag="KOU88_004123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBK3213930.1"
                     /translation="MIIHKFIIHVLDKNSDTPILNDFEGRVSQDIEAFFQKKISKVSR
                     DNDIRTA"
BASE COUNT          856 a          137 c          393 g          548 t
ORIGIN      
        1 aaaactattg atatagaaga tatgtttgaa cttaatttaa gagcaataag aaagagaaat
       61 gaaaaaataa aaaatgaaat tgagaaacaa ataaaatatg aagattcaga aataaaaact
      121 acaaatcgtg gtggaccagg aaaaattata aaaattttca atataaatac tggagaggta
      181 aagattctta agagtgctga agaagcaagt agatatataa aggttagtcg tagctatgca
      241 agttatttag ctagagaaaa taaatcaact gaggatggtt ggaaagcaga gtatattcaa
      301 ggagcgacag atggtattag caaatgtgga acaagtaatt aagttagctg aaaagatatt
      361 aaataagaaa aagtgttctg ttaataaagc tattgatata gctataaaaa tattaagtag
      421 gtatgagtgt gaggggatgt tagaaaaatg aatatattag ctattacaat gcttataata
      481 ggaagtttta tagctggtag agtttatgag tatagattga atctaaaaga gtgtgaaaat
      541 tgcgacaata aaagaggtgt ataagaatgg atgatagatt agaaattata aatgcttctg
      601 taaattatat acagatgata tgtgaaagtt caaatatagc tattatagca gagcgaggaa
      661 gagttagaat attagattta gaaactaaag aaaaatatga tttattaaaa aataaactcg
      721 aggaaatgtt agaagaaata taagtgaaaa tatctaatta agacagttta gagagttgca
      781 aaatgtcttt tggtataaat tattgttgaa gtgttttgtg actctcaaaa atgaaaatag
      841 agaggggaat aatataatgg atttaaataa aattatgaat gatgcactag tagagttaga
      901 ggaaaatggc tttgtagagg aagtagttaa aaaacaattg gcagaaacaa taaaaagagt
      961 tgtgaatgag gtttttggaa attggggtga ttttagtaaa aaaattgaaa aacatctaag
     1021 tgaaaatata aatataaatt tagataaatt agatatacaa aaatataatg tgctcgtagc
     1081 aactacagta aaagaaaaga ttgatatgac aatgaaggta gaagctattg aacacttaaa
     1141 aagaaattta gataacatgc ttgtaggtgc tgaaaaagaa tataaaatga gcgaattgtt
     1201 ggaaatatta aaaatggata aatatgatat tgatgaatat gaaggctatg aagattgcat
     1261 aacatttatt cttgatgaaa ataaatatgg ttcgggatgg attgaaattg ataaagaacc
     1321 aaataaaagt aaatacagat gtgaacactc tatattgttg agaaaagatg gaactattgc
     1381 atcatataga tacgagaata gagaaatatc atctaaagat ataatgagtg gatttgataa
     1441 ttttggagat ttgctattta aaatatttgc tcatgggtca aaaataattt tggatttagg
     1501 aaatgatata gaagattatg atttaacaaa tggagaagat tattaaaata ggggatggaa
     1561 caaatgtcaa agtatgtatt gagatggcaa aaaggattat tactagatga acgcaagata
     1621 aattattcat gtggaagtat agaaaattta aaaaagaaag ctgaattatt agctaaagat
     1681 gacaagatac tgcttgtaac aatagataaa gttgaagaag ttataaaaga tactagaagc
     1741 caaaaaatgg ctgaatattt tgaggatgaa ggggtggaag tatgataata cacaaattta
     1801 taatacatgt tttagataag aatagcgaca caccaatact aaatgatttt gagggtagag
     1861 tcagccaaga tattgaagct ttctttcaaa agaaaataag caaagtatca agagataatg
     1921 acatcagaac agct
//
LOCUS       DAFAZV010000144         1929 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFAZV010000144 DAFAZV010000000
VERSION     DAFAZV010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1929
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.152"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            85..201
                     /gene="rrf"
                     /locus_tag="KOU88_004124"
     rRNA            85..201
                     /gene="rrf"
                     /locus_tag="KOU88_004124"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            208..282
                     /locus_tag="KOU88_004125"
     tRNA            208..282
                     /locus_tag="KOU88_004125"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:240..242,aa:Asn,seq:gtt)
     gene            287..361
                     /locus_tag="KOU88_004126"
     tRNA            287..361
                     /locus_tag="KOU88_004126"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:320..322,aa:Glu,seq:ttc)
     gene            367..442
                     /locus_tag="KOU88_004127"
     tRNA            367..442
                     /locus_tag="KOU88_004127"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:400..402,aa:Val,seq:tac)
     gene            448..524
                     /locus_tag="KOU88_004128"
     tRNA            448..524
                     /locus_tag="KOU88_004128"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:482..484,aa:Asp,seq:gtc)
     gene            535..609
                     /locus_tag="KOU88_004129"
     tRNA            535..609
                     /locus_tag="KOU88_004129"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:567..569,aa:Thr,seq:tgt)
     gene            624..708
                     /locus_tag="KOU88_004130"
     tRNA            624..708
                     /locus_tag="KOU88_004130"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:658..660,aa:Tyr,seq:gta)
     gene            718..791
                     /locus_tag="KOU88_004131"
     tRNA            718..791
                     /locus_tag="KOU88_004131"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:750..752,aa:Gly,seq:tcc)
     gene            802..878
                     /locus_tag="KOU88_004132"
     tRNA            802..878
                     /locus_tag="KOU88_004132"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:836..838,aa:Arg,seq:tct)
     gene            888..963
                     /locus_tag="KOU88_004133"
     tRNA            888..963
                     /locus_tag="KOU88_004133"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:921..923,aa:Gln,seq:ttg)
     gene            975..1050
                     /locus_tag="KOU88_004134"
     tRNA            975..1050
                     /locus_tag="KOU88_004134"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1008..1010,aa:Lys,seq:ttt)
     gene            1053..1141
                     /locus_tag="KOU88_004135"
     tRNA            1053..1141
                     /locus_tag="KOU88_004135"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1087..1089,aa:Ser,seq:tga)
     gene            1159..1249
                     /locus_tag="KOU88_004136"
     tRNA            1159..1249
                     /locus_tag="KOU88_004136"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1193..1195,aa:Ser,seq:gct)
     gene            1258..1334
                     /locus_tag="KOU88_004137"
     tRNA            1258..1334
                     /locus_tag="KOU88_004137"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1292..1294,aa:Pro,seq:tgg)
     gene            1420..1495
                     /locus_tag="KOU88_004138"
     tRNA            1420..1495
                     /locus_tag="KOU88_004138"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1453..1455,aa:Trp,seq:cca)
     gene            1556..1632
                     /locus_tag="KOU88_004139"
     tRNA            1556..1632
                     /locus_tag="KOU88_004139"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Pro,seq:tgg)
     gene            1639..1715
                     /locus_tag="KOU88_004140"
     tRNA            1639..1715
                     /locus_tag="KOU88_004140"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1673..1675,aa:Ile,seq:gat)
     gene            1719..1794
                     /locus_tag="KOU88_004141"
     tRNA            1719..1794
                     /locus_tag="KOU88_004141"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1752..1754,aa:Phe,seq:gaa)
     gene            1802..1878
                     /locus_tag="KOU88_004142"
     tRNA            1802..1878
                     /locus_tag="KOU88_004142"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1836..1838,aa:Met,seq:cat)
BASE COUNT          493 a          442 c          521 g          473 t
ORIGIN      
        1 taactctaaa aaaaaataaa aaaagtattg acaaaaatag taaaaaatgt taatattata
       61 cttgtcctag caacaagaaa aaaatgtggt tataatagcg gagaagatac acctgtttcc
      121 attccgaaca cagaagttaa gttctctagc gctgatggta cttggtggga aactacctgg
      181 gagagtagga catagccacg tgaatgttcc aaggtagctc aacggtggag caaccggctg
      241 ttaaccggta ggctgtgggt tcgagcccca cccttggagc cattatggct cgttggtcaa
      301 gaggttaaga caccgccctt tcacggcggt aacaggggtt caattcccct acgagtcacc
      361 atttgtggga tcatagctca gctgggagag cacctgcctt acaagcaggg ggtcacaggt
      421 tcgagccctg ttggtcccac catttgcggc ctggtagttc agttggttag aatgccagcc
      481 tgtcacgctg gaggtcgagg gttcgagccc cttccaggtc gccaaaataa aaatgctggt
      541 gtggctcaac ggtagagcag ctgacttgta atcagcaggt tgtaggttcg attcctatca
      601 ccagctccat gtaaaactaa tacggaggat ttcccgagcg gccaaagggg gcagactgta
      661 aatctgttgt catcgacttc ggtggttcga atccaccatc ctccaccaat taaatatgcg
      721 ggtgtagctc aatggtagag ttctggcctt ccaagccagc tgtgagggtt cgatcccctt
      781 cacccgctcc aaagaaagcg tgggtgcata gctcagctgg atagagcaac gcccttctaa
      841 ggcgtgtgtc cggggttcga atccctgtgc gctcaccaca tatatattgg ggattagcca
      901 agtcggtaag gcacatgact ttgactcatg tatgcgtagg ttcgagtcct gcatccccag
      961 ccaaataaaa atatggtcta ttagctcagt cggtagagca cctgactttt aatcagggtg
     1021 tcccgcgttc gagtcgcgga tagatcacca atggagaggt gtccgagtgg tttaaggagc
     1081 tggtcttgaa aaccagtgac ttcgaaaggg gccgtgggtt cgaatcccac cctctccgcc
     1141 aaaaaaatga ctgaatttgg agaagtactc aagtggctca agaggatccc ctgctaaggg
     1201 attaggctgg gtaaccggtg cgagggttcg aatccctcct tctccgccat tcaaaaacga
     1261 ggtgtagcgc agtttggtag cgcacatggt ttgggaccat ggggccgggg gttcgagtcc
     1321 cttcacctcg accaacttaa gcttttagtt cagttggtta gagtgcccaa ctcatggcta
     1381 gtaattctag ggtttgagtc catgaaggtt attcttcata ggggtgtagc tcagttggta
     1441 gagcgtcggt ctccaaaacc gtgcgccggg ggttcgagtc cctccacccc tgccaaataa
     1501 aaaggacttg aaaaaagttg gattttagag tagtataaga tagtaaataa gatttcgagg
     1561 tgtagcgcag tttggtagcg cacatggttt gggaccatgg ggccgggggt tcgagtccct
     1621 tcacctcgac caagaaaagg gcctatagct caggtggtta gagcgcacgc ctgataagcg
     1681 tgaggtcgct ggttcgagtc cagctaggcc caccatttgc ccagatagct cagtcggtag
     1741 agcaggggac tgaaaatccc cgtgtcggtg gttcgattcc gcctctgggc accaggaata
     1801 cggcggtata gcttagttgg ctagagcgtt cggttcatac ccgaaaggtc ataggttcga
     1861 ctcctattac cgctaccatc taactatatc aataaagaac tttgaaaatt aaacagtagg
     1921 ttaatttat
//
LOCUS       DAFAZV010000145         1773 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFAZV010000145 DAFAZV010000000
VERSION     DAFAZV010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1773
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.153"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..628
                     /locus_tag="KOU88_004143"
     CDS             <1..628
                     /locus_tag="KOU88_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004454768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF2156 domain-containing protein"
                     /protein_id="HBK3213931.1"
                     /translation="RGITTEVVEFLKEKYPGRFEYIEERDLFDYIYDAESLRTLAGKK
                     NQKKRNHINYFLKEYAGRYEAKLLDKENFDECLVLMKEWESNKEENNEFDESMDDELI
                     GIKKIFNHYDILKDKVKVFGVYVDGKLEAFSIGELLNPNMALIHIEKANPDIRGLYPF
                     INQQFLVSEFKDVEFVNREEDLGIEGLRKAKLSYHPCRFVEKYSVREA"
     gene            637..>1773
                     /locus_tag="KOU88_004144"
     CDS             637..>1773
                     /locus_tag="KOU88_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009893611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK3213932.1"
                     /translation="MEIRYAKEEEIESIKEIWSYCFNDTESFMKYYFNDKYKSENTVV
                     ALDEGKIISSLQLNQYKLLLNSKVYNTSYVVGVSTLPEGRGAGYMNKVMKFTLNELYK
                     KGQLVSILMPIDYRLYRRFGYEHCYDQIEYTINTDDLKNFKSSGKMIKSNLSQIDDLI
                     QIDRTFLNEVNGNVLKDEHYYENLFKEIQSEDGFLYIHEGNEKDGYIVYFLQEDKMFV
                     RELFYKNIDALKSMLKFIYNHNTQCKIVTISTPTIDKIRFILDNPKDSDIKIKPFMMG
                     RVINVKKFIEDIDIENDINSSFNLLIEDKFIDENNGLFKISIQNKKVSVEQLDKKGAE
                     KPQEDFDIKLDINTLTQLSFSYIDVNEAIFLNDIKDVSEETLETL"
BASE COUNT          733 a          148 c          320 g          572 t
ORIGIN      
        1 aagaggtatt actactgaag tagtagagtt tttaaaagaa aaatatccag gtagatttga
       61 gtatatagaa gaaagagatt tatttgacta tatttatgat gcagaaagtt taagaactct
      121 agctggtaaa aagaatcaaa agaagagaaa ccatataaac tatttcttaa aagagtatgc
      181 aggtagatat gaagctaaat tattagataa agaaaacttt gatgagtgtt tagtactaat
      241 gaaggaatgg gaaagtaata aggaagaaaa taatgaattt gatgaaagta tggatgatga
      301 attaataggt atcaaaaaga tatttaacca ttatgacata ttaaaagata aggtaaaagt
      361 gtttggtgtt tatgtagatg gaaaattaga agcttttagt ataggagaac ttttaaatcc
      421 aaatatggca ttgattcata tagaaaaagc taatcccgat ataagaggtc tgtatccatt
      481 tataaatcaa caatttttgg taagtgaatt taaggacgtt gagtttgtaa atagagaaga
      541 agatttaggt attgaaggat taagaaaagc taaactttct tatcatcctt gcagatttgt
      601 tgaaaagtac agtgttaggg aggcttaata gactatatgg agattaggta tgctaaagaa
      661 gaagagatag aaagcataaa agagatttgg agttattgtt ttaacgatac ggagagtttt
      721 atgaagtact attttaatga taaatataaa tctgaaaata ctgtagtagc tttagatgaa
      781 ggaaaaatta tttcttctct tcagctaaat cagtataagt tattactaaa tagcaaggta
      841 tataatacat catatgtagt aggagtttct acacttccag agggaagagg agctggatat
      901 atgaacaaag taatgaaatt tactttaaac gaattgtata aaaaagggca attagtttct
      961 atattgatgc ctattgacta tagactttat agaagatttg gatatgagca ttgttacgac
     1021 cagattgaat atactattaa cacagatgat ttaaaaaatt ttaagtcaag tggaaaaatg
     1081 ataaagtcta atttatcaca aattgatgat ttgatacaaa tagatagaac ttttttaaat
     1141 gaggttaatg gtaatgtgtt aaaagatgaa cattattatg aaaacttatt taaagagatt
     1201 caaagtgaag atggattttt atacattcat gaaggaaatg aaaaagatgg atatatagtt
     1261 tattttcttc aggaagataa aatgtttgtc agagagttat tttataaaaa tatagatgcc
     1321 cttaaatcaa tgcttaaatt tatatataat cacaatactc aatgtaagat agttactata
     1381 tctactccta caatagataa gataaggttt atattagaca accctaaaga tagtgatata
     1441 aaaataaaac cttttatgat gggaagagtt ataaatgtaa agaagtttat tgaagatata
     1501 gatattgaga atgatattaa tagctcattt aatttattaa tagaagacaa gtttatagat
     1561 gaaaataatg gtctatttaa aatttctata cagaataaga aggtatctgt agagcagtta
     1621 gataaaaaag gtgcagaaaa gcctcaagaa gattttgata ttaaattaga tataaatacc
     1681 ttaacacagt tatcattttc ttatatagat gtaaatgaag ctattttctt aaatgatata
     1741 aaagatgttt cagaagaaac actagaaaca ctt
//
LOCUS       DAFAZV010000146         1762 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFAZV010000146 DAFAZV010000000
VERSION     DAFAZV010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1762
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.154"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     misc_binding    704..967
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1118..1669
                     /locus_tag="KOU88_004145"
     CDS             1118..1669
                     /locus_tag="KOU88_004145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003424155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan transporter"
                     /protein_id="HBK3213933.1"
                     /translation="MKTNTKKLTLNAILLAMGLLIHQITPAIGLPMKPDVPLAMLFVI
                     LVLNRDDYKTCLIAGIVTGIFTALTSSFPGGQIPNVIDKTLTANIVFLLMNISYNMPF
                     IKKLAKKTQDTVVVAIIMPIGTLVSGTIFLLAAQAIVGLPGASFTALFLAVVLPAVLI
                     NLVAGIFLFKIVSLSIRRVSYQA"
BASE COUNT          743 a          170 c          264 g          585 t
ORIGIN      
        1 ttatacatat gataatacta aatttaaaac tattaaatct aaaagtagac ataaaagtag
       61 gaaatataat aaaagtaaag taaagttgaa aaaacgaagt ataagaacta aaaagtatgg
      121 atatcaaact ataaataaat ataaaagaca aaacgcaaga agacataata tcctaacaaa
      181 attaatattg tccataatag tcatattttt ggttatagtt ttagtagtgc taatatttat
      241 taaaagaaag aagaaaaaat tttactaaaa ataattaaaa gaatatcatt tttttaatca
      301 ttggtatcta tttaataata tgatgtaatt aaaatggagt aatattctgt ttcaaaggag
      361 gcatataaat acaggaatga gtattaaatg atggttaatt aagtaaattt attgataaat
      421 gtacttaatt aactttgaag aatttaattc ctcatgaatc aaaatataaa attacatcaa
      481 cagttattca caaaattaat ataagaagaa ttagagccaa agagcagact attagaccat
      541 taaagtaatt attcatagaa ttttgtatat gaaaagaaat gtatagtata atttactttt
      601 tttataaaaa atagattaca aaatatattt tttataaaaa ggtattgaca ttttttagaa
      661 aaaagaatat cattatttta acaacaaaat tcaatacaat aaattaaatc ctatgacaag
      721 gaagagtagt taaatttagg ttcagtatag agagctgagg atggtggaat cttagcaaga
      781 aaaaatttga tgaatggccc ttagaggaat aaattgaaat catagttttg agagtagact
      841 ttatcgtcag tcgcacgtta tagcgaataa ggtatgtaag tacctgataa tgagatgtat
      901 gaaaattgaa ttttatatta atttttatat aatttaggtg gcaacgcgga taatctccgt
      961 cctattagtt taggacggag ttttttattt tactgaaaat ttaaaagata gaaggtggtg
     1021 agaaagatgt tatgaatttc aaaagctaaa gatgatgata tagtaggttg gcaaaaaaat
     1081 aaattgaaaa ttaaaaaaat aggaggaagt acaaaaaatg aaaacaaata caaaaaaatt
     1141 aactttaaat gcaatacttt tagcgatggg attattaata catcaaatca caccagctat
     1201 aggattacca atgaagccag atgtaccact agcaatgtta tttgtaatat tggttttaaa
     1261 tagagatgat tataaaactt gtttgatagc gggtatagta acaggaatat ttacagcact
     1321 tacatcaagt tttccgggag gtcaaattcc taatgtaata gataaaactc ttacagcaaa
     1381 tatagtattt ttattaatga atattagtta taatatgcct tttataaaaa aattagctaa
     1441 gaaaacacaa gatactgtag tagttgcaat aataatgcca ataggaactc ttgtaagtgg
     1501 aactatcttt ttattagcag ctcaagctat agttggtctt ccaggggctt catttacagc
     1561 tttattctta gcagtagtat taccagctgt tttaataaat ctagttgcag gaatattttt
     1621 attcaagatt gttagtctat caataagaag agttagttat caagcttaaa cacgaaataa
     1681 tattttactt tataaagcat tataataact aaataacata agaataaagt agattataac
     1741 tattttattc ttatgttgtt ta
//
LOCUS       DAFAZV010000147         1746 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFAZV010000147 DAFAZV010000000
VERSION     DAFAZV010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1746
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.156"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(24..509)
                     /locus_tag="KOU88_004146"
     CDS             complement(24..509)
                     /locus_tag="KOU88_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213934.1"
                     /translation="MGKMDKKEAKKFLKVVDMNIDKIKEEATKIYKECYLIETTDTIR
                     ISINLKGVVKSTISSWQGYSDDIFNMREIIFYEFSQGEVQIEDLLGELCFLNDYEEFA
                     TWCDTESETLNWNSYEKFNKENFDELVERNIEDSLPDFLEELSESIENCKQELKSMIE
                     I"
     gene            complement(645..977)
                     /locus_tag="KOU88_004147"
     CDS             complement(645..977)
                     /locus_tag="KOU88_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213935.1"
                     /translation="MKKYFKEEWNYIADAGYEIDNIESTKIMVNNFEVSIKMSEDFKH
                     KGDIEYTFNIPYDHEIFTKEYNEVLNLEQPCDCDQFCDELSDLRARIEEGIEKYLKDN
                     DKLKEIEY"
     gene            complement(1064..1411)
                     /locus_tag="KOU88_004148"
     CDS             complement(1064..1411)
                     /locus_tag="KOU88_004148"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213936.1"
                     /translation="MCDIGKRIKILIENEKIKQVEFANKIKVDPSYISKFLSDKSKVI
                     PSDRLIDDICSTFNVNKEWLKNGDGEMYIENKCNRNISEATDLLMELSIEFQECAINQ
                     IKDLIKLQHSLKK"
     gene            complement(1417..>1746)
                     /locus_tag="KOU88_004149"
     CDS             complement(1417..>1746)
                     /locus_tag="KOU88_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3213937.1"
                     /translation="NLSQPDFGGKLGVSKDVISNIEYDRVEPKPLLINHLCSVFNVNK
                     EWLINGTGDMYVSVKEDISSILGEVFYKIASSKDENLKELIINISKLDATYIASLNEI
                     VKRSIQR"
BASE COUNT          542 a          304 c          142 g          758 t
ORIGIN      
        1 cattaataat aatactcttt catttaaatt tcaatcattg attttaattc ttgtttacaa
       61 ttttctatac tttcgctcaa ttcttccaaa aaatctggta aactatcttc tatatttctc
      121 tcgactaatt cgtcaaaatt ttctttgttg aatttttcat aactattcca attcaaagtt
      181 tcgctttcag tgtcacacca agtagcaaat tcttcgtaat catttaaaaa acaaagttct
      241 cctaaaagat cttcaatttg aacttctcct tgactaaatt catagaaaat aatttctctc
      301 atattaaaaa tatcatctga atagccttgc caacttgaaa ttgtgctttt tacaactcct
      361 ttcaaattta tagaaattct tatagtatca gttgtttcta ttaagtagca ttctttataa
      421 attttcgtag cttcttcctt tattttatct atattcatat ctacaacctt taaaaatttt
      481 ttagcttctt ttttatccat tttacccata ttaatttcct cctattttaa aatattattc
      541 aagatatatc tgtatttttg tattaaaaaa actgtattat aacaatacag ctttatgatt
      601 tttatattca attttataat tttttaaaat aaattcaatt acatctaata ttctatttct
      661 tttaacttgt cattgtcttt taaatatttc tctatgcctt cttcaatcct tgctctaagg
      721 tctgatagtt catcgcaaaa ttggtcgcaa tcgcaaggtt gttctaaatt caaaacttcg
      781 ttgtactctt ttgtaaaaat ttcatggtca tatgggatat taaaagtata ttctatgtca
      841 cctttatgtt taaaatcttc actcattttt atgcttactt caaaattatt taccattatt
      901 ttagtacttt ctatgttgtc tatttcatat cctgcatcag caatatagtt ccattcttct
      961 ttgaaatact ttttcatata aatcactctt tttattttaa aatctttctt aattctatta
     1021 aatttaatct tataatttca tctttttcag acattaatct ctcctacttt tttaatgaat
     1081 gttgcaattt tattaagtct ttaatttgat taattgcaca ttcttgaaat tcaattgaaa
     1141 gttccattaa taagtcagtc gcttctgaaa tattcctatt acacttattc tctatgtaca
     1201 tttctccatc tccattttta agccattctt tattaacatt gaatgtacta caaatatcat
     1261 ctattaatct atcgctaggt attactttag atttatctga tagaaactta gatatataag
     1321 atgggtcaac ttttatcttg tttgcaaact caacttgttt tattttttca ttttctatta
     1381 agattttaat tctcttgcct atatcacaca ttaatatcac ctctgtattg acctttttac
     1441 aatctcattc aaagacgcta tatatgtagc atctaattta gaaatgttaa ttattagttc
     1501 ttttaaattt tcatcctttg aactagctat cttatagaac acttctccta aaatcgaaga
     1561 aatatcttct tttacagaaa catacatatc acctgtacca tttataagcc attccttatt
     1621 aacattaaat acactacata aatgattaat aagtaaaggt ttgggttcaa ccctatcata
     1681 ctctatatta cttataacat ctttgctgac acctaatttt cccccgaaat ctggctgaga
     1741 taaatt
//
LOCUS       DAFAZV010000148         1743 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFAZV010000148 DAFAZV010000000
VERSION     DAFAZV010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.157"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            286..456
                     /locus_tag="KOU88_004150"
     CDS             286..456
                     /locus_tag="KOU88_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007049581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HBK3213938.1"
                     /translation="MSSKIGRPKVDNPKNVDVKVRFDENTHKKLLDYCEKENITRTEA
                     IRKGVDLLLENK"
     gene            578..1321
                     /locus_tag="KOU88_004151"
     CDS             578..1321
                     /locus_tag="KOU88_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007488404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin Bro"
                     /protein_id="HBK3213939.1"
                     /translation="MNNLQIFKNNDFGEIRTIEIDNEVWFVGKDVAIALGYANTREAL
                     KTHIDSEDIADVVIHDGSQNRNMKITNESGLYSLIFGSKLPTAKKFKNWVTKEVLPSI
                     RKTGSYDINNLEERVAPMIFNGILAGIKQVAIENDKKIDTRFNQIEDKLDKKYKKQDK
                     QFQEMKNMIGFKAKNTRMLSKLLKIKLSEIKGYNVNAYNYDYRTVVTRLFSIYNVTKW
                     EDIPVTKFNEVHAMIDGIESMDDVYTWNH"
     gene            1336..1674
                     /locus_tag="KOU88_004152"
     CDS             1336..1674
                     /locus_tag="KOU88_004152"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213940.1"
                     /translation="MCIIKTVYKFDGDILQRNAKRVQMIRDIKGSSNLTIIIKRFLDN
                     VKDYNFKNVRYIIENELFFERISVDMICRYMDTLNKYENIECIFEEAYILKGENGFRR
                     TVDYLVRQTY"
BASE COUNT          731 a          144 c          325 g          543 t
ORIGIN      
        1 aacataaatg acaacaaatg tatatatttt gttgacattt tgatatggtg ctattatact
       61 aaaattaaga taacaaaata tatacgaatg ttatcatgtg ttgtcttgat tttagtataa
      121 tattattttt aggttgatag aggttttgtt tggagattga taatatatga aattcctcaa
      181 attgattaat taaaaaaata attagaaaaa tctggataat atattgactt tttggaacgc
      241 aaataatatg attatattgt ggaacacaaa aagtgaggtg aaacaatgag ttctaagata
      301 ggaagaccaa aagtagataa tcctaaaaat gttgatgtta aagtaaggtt tgatgaaaat
      361 actcataaga aattgttaga ttattgtgag aaagaaaata ttactagaac agaagcaata
      421 agaaaaggag tagatttact tttggaaaac aaataaaaag tagcccacat accgaccaaa
      481 gtaacgatgg actactttat acaagaagtt atcttctatg aaatattcta tcatagagag
      541 gtacttctta caatcaattt ggggaggatt ttgtatgatg aataatttac aaatatttaa
      601 aaataatgat tttggagaaa taagaacaat agagatagat aatgaggttt ggtttgtagg
      661 caaagacgta gctatagcat taggttatgc taatacaaga gaagcgttga agactcatat
      721 tgatagtgaa gatatagctg atgtcgtaat tcacgacggc agccaaaata gaaacatgaa
      781 aataacaaat gaaagtggat tgtattcttt gatatttggt agtaaattac caactgctaa
      841 aaaatttaaa aattgggtta ctaaagaagt cttaccaagt ataagaaaaa ctggttcata
      901 tgatataaat aatttagaag aaagagtagc tccaatgata tttaatggta tacttgctgg
      961 gattaaacaa gttgcaatag aaaacgataa gaaaatagat actagattta atcaaataga
     1021 agataaatta gataagaaat ataagaaaca agataagcaa tttcaagaaa tgaaaaatat
     1081 gataggattc aaagctaaga acacacgaat gttgtcaaaa ttgctaaaga taaagctatc
     1141 ggaaataaaa ggatataatg taaatgctta taactatgat tatagaactg tagtgacaag
     1201 attattttca atatataatg taactaagtg ggaagatata ccagttacta aattcaatga
     1261 ggttcatgcc atgatagatg gaatagagag tatggatgat gtatatactt ggaatcatta
     1321 ggatggtgac tgtttatgtg tataattaaa acagtttaca aatttgatgg ggatatattg
     1381 caaagaaatg ctaaaagagt tcagatgata agggatataa aaggtagtag taatttgacg
     1441 attataatta aaagattttt agataatgta aaagattata attttaagaa tgtgagatac
     1501 ataatagaaa acgagctatt ctttgaaagg atttctgtcg atatgatatg tagatatatg
     1561 gatacattga ataagtatga aaatatagaa tgtatatttg aagaagctta tatattaaag
     1621 ggagagaatg gatttagaag gactgtagat tatttggtca gacaaacata ttgatggata
     1681 agttaaaaat attaaggcag cttatatagc tgtctttttt gtatagaata aaaaagttta
     1741 tta
//
LOCUS       DAFAZV010000149         1713 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFAZV010000149 DAFAZV010000000
VERSION     DAFAZV010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1713
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.158"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(160..336)
                     /locus_tag="KOU88_004153"
     CDS             complement(160..336)
                     /locus_tag="KOU88_004153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018592638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBK3213941.1"
                     /translation="MEKRILKVLLSKSGSGSLSPKISLPATWIKEMNITQEEREVEVY
                     FENNEIRIKKKDLD"
     gene            complement(746..1246)
                     /locus_tag="KOU88_004154"
     CDS             complement(746..1246)
                     /locus_tag="KOU88_004154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016056376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213942.1"
                     /translation="MASKVKKEFFMATKKHLENYKQLHINIESLKLQIKNLKEFHLGD
                     FMQGLSYDSIPISKTNSISNQVENELINLEEKIIEKQIELYEMEALKYTIDVSISNLK
                     PIHKQIIRYRYIEGLEWSLIVDKVYLEERQLRERANQAISSISIALFGKKALIEQEPL
                     FKMLDL"
     gene            complement(1265..1681)
                     /locus_tag="KOU88_004155"
     CDS             complement(1265..1681)
                     /locus_tag="KOU88_004155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015615683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBK3213943.1"
                     /translation="MSKYNNKKIVIDGIKFDSKDESEYYLYLKEKKENGEIKDFGLQQ
                     KFELQPKFKKDGKSYRAITYTVDFAIYKWNGEVVYIDVKGYSTQQGELRKKLFDYKYQ
                     DKKLIWIAKSKKYGVDGWIEYSELKKKRKENKKKVA"
BASE COUNT          486 a          321 c          174 g          732 t
ORIGIN      
        1 tcacgccctg cctagtctgt tcatataagc taggtgaatc cctttaccta gcccacatat
       61 atttagtttt gagagagaaa tattcatttc cacaatacta ttatctcaca ctttaaattg
      121 taaaatcggc agaaaaacgg caataaaaag acctagaatt taatctaggt ctttcttttt
      181 aatcctaatt tcattatttt caaaataaac ttcaacttct ctctcttctt gtgttatatt
      241 catttcttta atccatgttg caggtagact tattttagga cttagtgaac cagagccact
      301 ttttgataag agtactttca atattctttt ttccatttct ttctctccct ctaggaaaat
      361 aaatatttta tagcaaatat taataatgct attgcaccaa ttaatttaac tataccaaaa
      421 cttaatttcc ctaattctgt aattaattcc ttatattttc ccattgtatt ttgagtggtc
      481 atgtattatt atttaattag aagggaaggt gctgactccc cttctaaagt cttataggct
      541 atctaatacc atttttataa cggctattag tgtacctatt tcaagagcaa gttcggtaag
      601 ggctttgaca actttgccga actcttttat ttttttgacc acttctttca cctcctttct
      661 atatttatat tatatcatgt cgtaccgata taatcaatac ctttttccct ttttttagta
      721 aaaaaaatag acagctattc actgcctata aatctaacat cttaaataat ggttcttgct
      781 ctattagtgc tttctttcca aacaaggcta ttgatattga actaatggct tgattagctc
      841 tttctcttaa ttgtctttct tctaagtata ctttatcaac tattaaactc cattctaagc
      901 cttcaatata cctatacctt ataatttgtt tatgtatagg ttttaaattg cttatggata
      961 catctattgt atattttagt gcttccattt catataattc tatctgcttt tctattatct
     1021 tttcttcaag attaattaac tcattttcaa cttgattact tattgaatta gtcttactta
     1081 tgggaatgct gtcatagctt aaaccttgca taaaatcacc taaatggaac tctttaagat
     1141 tttttatttg aagttttaga ctttcaatat taatatgtag ttgtttgtag ttctcaaggt
     1201 gttttttagt tgccataaaa aactcctttt taactttact tgccataaca tcactcctat
     1261 ttatttaagc tacctttttc ttattttctt ttctcttttt cttaagttca ctatattcta
     1321 tccaaccgtc taccccatat tttttgcttt tagcaatcca tatcaatttt ttgtcctgat
     1381 atttatagtc aaaaagcttt tttctaagtt caccctgctg tgtactatac cctttcacat
     1441 ctatataaac gacttcacca ttccatttgt atatggcaaa atcaactgta tatgtaatag
     1501 ctctgtagct tttcccatct tttttaaatt taggttgtag ttcaaacttt tgttgaagtc
     1561 caaagtcttt tatttctcca ttttcctttt tttcttttaa atataaataa tactctgact
     1621 catctttact atcaaattta attccatcta ttacaatttt cttattattg tatttactca
     1681 atcaaatact tcctttatca cttaaagtta ctc
//
LOCUS       DAFAZV010000150         1691 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFAZV010000150 DAFAZV010000000
VERSION     DAFAZV010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1691
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.159"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..769)
                     /locus_tag="KOU88_004156"
     CDS             complement(<1..769)
                     /locus_tag="KOU88_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009527294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK3213944.1"
                     /translation="MFMINIVIPNYNGYKLLKNCLDSLKNQTYSNFSIIVVDNASDDS
                     SYNWLNNYENVTLKKLDKNYGFSKAVNEGIKLSNSKYVVLLNNDTVVPENWLETLLGE
                     IEKDESIFSVCSKMIRYNEKDKIDDAGDEYSILGWAYKIGDGKNISSFRKSKYVFSSC
                     AGAAIYRNSIFDEIGYFDEDFFAYMEDIDISYRAKIYGYKNRYCSEAKIFHIGSATSG
                     SKYNSFKVRLAARNNVYVPYKNMPFLQLIINMPFLIIG"
     gene            complement(816..1667)
                     /locus_tag="KOU88_004157"
     CDS             complement(816..1667)
                     /locus_tag="KOU88_004157"
                     /EC_number="2.4.2.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decaprenyl-phosphate phosphoribosyltransferase"
                     /protein_id="HBK3213945.1"
                     /translation="MLLEYIKLMRPKQYIKNGFVLAALIFSNNILNPSLALKSILSFI
                     AFCMISSSAYILNDILDIEKDKMHPKKCKRPLASGSIGKKGAISLGIVLVLSSILLSL
                     LIHKNLCVIILLYLFNNIMYSLKLKNIILIDVFSIAIGFILRVCAGSIAINVSLSSWI
                     ILCTFFLSLYLGFGKRKKEIILLKEDASNHRKILKEYDEENLNQMMSISLSATIVCYS
                     LYSANNIYNSNMIFTTVFVVYGVLRYNYIVNIGDEGNPTDVVLNDKSLKFCVLFWVIA
                     CIGILST"
BASE COUNT          601 a          266 c          158 g          666 t
ORIGIN      
        1 aaccaataat taaaaaaggc atgtttatta taagctgtaa aaaaggcatg tttttatatg
       61 gtacatatac attgtttcta gcagccaatc ttactttaaa tgaattatat ttacttccag
      121 atgtagcact ccctatatga aatatttttg cttctgagca atatctattt ttatatccat
      181 aaatttttgc tctataagat atatcaatgt cttccatata tgcaaaaaaa tcttcatcaa
      241 aataacctat ctcatcaaaa attgaatttc tatatatagc agcacctgca caagaactaa
      301 atacatattt actttttcta aaacttgata tgttcttacc atctccaatt ttgtaagccc
      361 agcctagtat agaatattca tctccagcat catctatttt gtccttttca ttatatctaa
      421 tcattttgct acatacggaa aaaatactct cgtctttctc aatctctcct aatagtgtct
      481 ctaaccaatt ttcaggtact actgtatcat tgtttaacaa aacaacatat ttcgaattag
      541 ataattttat accttcattt actgccttac taaaaccata gttcttatct aattttttca
      601 gtgtaacatt ttcatagttg tttagccaat tatatgaact atcatctgat gcattatcta
      661 ctactattat actaaaatta gaatatgttt gattttttaa tgaatctaga caatttttta
      721 aaagtttata tccattataa tttggtatta ctatatttat catgaaaatt ctccatcttt
      781 tcaactttaa attttatttt aatatgtaat taactctaag tacttaaaat tccaatacac
      841 gcaattaccc aaaataaaac acaaaacttt aaacttttat catttaatac aacatcagta
      901 ggattacctt catcccctat attaactata taattatatc ttaaaacacc atatacaaca
      961 aacacagtag taaatatcat atttgaatta taaatgttat ttgctgagta taatgagtag
     1021 cacactatag tcgcacttaa agatattgac atcatttgat ttaggttttc ttcatcatat
     1081 tcttttaata tttttctatg attacttgca tcttctttaa gtaatattat ttcttttttt
     1141 cgcttcccaa aacctaaata taaagataaa aagaatgtgc ataaaattat ccaacttgat
     1201 aaactaacat ttattgctat agacccagca caaactctca gtatgaatcc tatggctata
     1261 gaaaatacgt ctattaatat tatatttttt aatttgagtg aatacataat attgttaaat
     1321 aagtacaata atattattac acatagattt ttatgtatta ataaggataa taaaattgaa
     1381 gataaaacta atacaatacc taatgaaatt gcccccttct ttccaattga tccactagct
     1441 agaggtctct tgcacttttt aggatgcatc ttatcttttt ctatatctaa aatatcattt
     1501 agtatatagg ctgatgatga tatcatacaa aatgctataa aagataatat agattttaac
     1561 gctaatgatg gattgagtat attgtttgaa aatattaatg cagctaaaac aaatccgttt
     1621 ttgatatatt gttttggtct cattaattta atatattcta ataatatatt tctattatat
     1681 tttctttgtt t
//
LOCUS       DAFAZV010000151         1688 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFAZV010000151 DAFAZV010000000
VERSION     DAFAZV010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1688
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.160"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            1..273
                     /locus_tag="KOU88_004158"
                     /pseudo
     CDS             1..273
                     /locus_tag="KOU88_004158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003422009.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            316..1224
                     /locus_tag="KOU88_004159"
     CDS             316..1224
                     /locus_tag="KOU88_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003429501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conserved phage C-terminal domain-containing
                     protein"
                     /protein_id="HBK3213946.1"
                     /translation="MELDCVCNDEFIDNSGIEFDCDSKDNSFNGDINVETVHCINEYF
                     SDDDVEHNYNNFHNKDTIKDKAISNISTIKKYIDESFDTNKSENSNLQQESINFNFND
                     TCNEIDKRTNNSIENNQNKRPMRLSDISLLSDKGMTNKKNYFNHNHGIQKGTKSVTKK
                     KESLNKFNKKNIQQSIINMLNKKSGKNFKIDSPISIKLINERLKEGYVLEDFYKVIEV
                     KVAKWKNTIMEMYIRPETLFSYKFESYVNENISMKSQSNVHPCKEGNSNDSSNYIHSD
                     YITYDGSVRERKKYENVRYWNPICEI"
BASE COUNT          719 a          146 c          281 g          542 t
ORIGIN      
        1 tacaaattaa attcagtggt attgaacttt gatattaaga atgatgttaa caagataaga
       61 tttaatcatt atataatgag aaaagaaaac atacaaagac ttcaaggaac tctgccaaac
      121 ggacaatttt atatgacagt gagaagagct gctacagatt tacaactttc tatttctact
      181 ataagtaggc ttgtaaaaga gtttttggat ttagggataa taagattagt gtctaagggt
      241 gtaaaaggta atcgttctgt atatagttac gtaagtatag agtttaatgg aagtttattt
      301 gatgatagta aatatatgga acttgactgt gtatgtaatg atgaatttat tgataatagt
      361 ggcatagagt ttgattgtga tagcaaagat aattctttta atggagatat aaatgtagaa
      421 actgtgcatt gcattaatga gtatttctct gatgatgatg tagagcataa ttataacaat
      481 ttccataaca aagatactat aaaggataaa gccatttcta atattagcac tatcaaaaaa
      541 tatattgatg aatcttttga tacaaataaa tcagaaaatt ctaacttaca acaggagtca
      601 ataaatttca actttaatga tacatgcaat gaaatagata aaagaacgaa taatagtata
      661 gaaaataatc aaaataaaag gcctatgaga ttgagtgaca tcagtctttt aagtgataaa
      721 ggtatgacaa ataaaaagaa ttactttaat cataatcatg gtatacaaaa agggactaaa
      781 tctgtaacaa agaaaaaaga atccttaaat aaatttaata aaaaaaatat acagcaaagc
      841 attataaata tgctaaataa aaaatcaggt aagaatttta aaatcgattc tccaataagc
      901 ataaaactta tcaatgaaag gctaaaggaa ggctatgtct tagaagattt ctacaaagtt
      961 attgaggtaa aagtggctaa gtggaaaaat accataatgg aaatgtatat aagaccagaa
     1021 actttgttta gctataagtt tgaatcctat gtaaatgaaa acatatctat gaaaagtcaa
     1081 agtaatgttc acccatgtaa agaaggcaat agtaatgata gcagtaatta tatacattct
     1141 gattatataa catatgatgg cagtgtgcgt gagagaaaaa aatatgagaa tgtaagatac
     1201 tggaatccta tatgtgaaat ttaattagtt taaaaatgta tttatgataa ataagatatt
     1261 aatagagaat agtgagctat agcaaatgat atatcaatag ttggtagtaa gttatattaa
     1321 gtaagatatt actatcaggt agtgaattat attgaacgat atattaataa ttggcagtaa
     1381 gttatatcaa ataagatatt actatagagt aatgaattat attgaacgat atattaataa
     1441 ttggcagtaa attatattaa ataagatatt actatagagt aatgaattat attggacgat
     1501 atatcaatag ttggtagtaa gttatattaa gcaagatatt actatcaggt agtgaattat
     1561 attgaacgat atatcaataa ttggtagtaa attatattaa gtaagatatt actatcaggt
     1621 agtgaattat attgaacgat atattaataa ttggcagtaa attatattaa ataagatatt
     1681 aatattgg
//
LOCUS       DAFAZV010000152         1662 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFAZV010000152 DAFAZV010000000
VERSION     DAFAZV010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1662
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.161"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            179..1615
                     /locus_tag="KOU88_004160"
     CDS             179..1615
                     /locus_tag="KOU88_004160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein Cwp28"
                     /protein_id="HBK3213947.1"
                     /translation="MKFYKRILTLTLSISFVFANIQLVDAISSVEKIQGKNKYEIAGK
                     IADKNAYKTAILINTSNSIADGLSASGLAGALNAPILLTEKNTIPTETSARLKNVSKV
                     YIIGGTYSISTSVENSLKSKKMKVVRIKGNDRIKTSYNVAKEINSIKKVNTVMLTNAY
                     KGEADAISIASVAARDKAPIILTNGQSIPFSTSGLKSYVIGGTASMSTTLVNNTKSTR
                     LGGSTRFETNKAIINKFYKDAREFYIAGAYELTNALVGSSLSKHGPMVLVNDGSNKSI
                     LKNAKKITSIGYIDSNIVQQCLNITNGIGDINTGVVKNVKPTTKTIKDGMYKVGKDIS
                     AGEYLITSNSGSYASYYEVTSDSTGNADSILSNDIFSGTRYITLKNGQYIKIEDSTMT
                     LAKYAKAQKAKNGKFGNGMYKIGLEIPAGEYIIMSNSSDAYYEVRNDSLGNAEGIVTN
                     DTFSGRRYITVEEGQYLILNDCYLIENE"
BASE COUNT          680 a          167 c          280 g          535 t
ORIGIN      
        1 tagttgattt ttaatataaa tgtaaataca attatagcta aatgaataat tgtattaata
       61 tttatttgta atatgcttaa tataatttgc aattttacat aagtttgtta agtacataac
      121 taatttaaga atatgtattt atatattaaa aatttattat gagggggaca attttattat
      181 gaaattctat aaaagaatat taacattgac tttaagtatt tcttttgtat ttgcaaatat
      241 tcaattagta gatgcaatat catctgtaga aaaaatacaa ggaaaaaata agtatgaaat
      301 cgcaggtaaa atagcagata aaaatgcata taaaactgct atattaatta atactagtaa
      361 ctctattgca gatggattaa gtgcaagtgg actagcagga gctttaaatg cccctatact
      421 attaactgaa aaaaatacta taccaactga gacatctgca agattaaaaa atgtatcaaa
      481 agtttatata attggaggaa catattctat tagtacatct gtcgaaaatt cattaaaatc
      541 taagaaaatg aaagttgtaa gaattaaggg aaatgacaga ataaaaacaa gttataatgt
      601 tgcaaaagaa ataaattcaa taaaaaaagt caatactgtt atgctaacca atgcatataa
      661 aggagaagca gatgctataa gtattgcatc tgtagcagca agagataaag caccaataat
      721 tcttactaat ggacaaagta tacctttttc aactagtggt ttaaagtctt atgtaatagg
      781 aggaacagct tcaatgagta ccactttagt aaacaatact aaatctacta gactaggggg
      841 gagtactcgt tttgaaacta ataaagcaat aataaataag ttttataagg atgctagaga
      901 gttttatata gctggagctt atgaattaac aaatgcactt gtaggatctt ctttatcaaa
      961 acatggtcca atggttttag ttaatgatgg tagcaataaa agcattttaa aaaatgctaa
     1021 gaagataact tctataggat atatagattc aaatatagta caacagtgtt taaatataac
     1081 aaatggaatt ggagatatta atactggggt tgtaaaaaat gttaaaccta ctacaaagac
     1141 tataaaagat ggaatgtata aggttggaaa agatatctca gcaggtgaat acttaataac
     1201 ttcaaactca ggaagttatg cttcttatta tgaagttaca agtgatagta caggtaatgc
     1261 tgatagtata ctttcaaatg atatttttag tgggactaga tatatcacct taaagaatgg
     1321 tcaatatatt aaaattgagg attcaacaat gacattagca aagtatgcta aagcccagaa
     1381 ggccaagaat ggtaagtttg gaaatggtat gtataaaatt ggattagaaa ttcctgctgg
     1441 agaatatatt ataatgtcaa attcttctga tgcatattat gaagttagaa atgatagctt
     1501 aggtaatgca gagggaatag ttactaatga tactttttca ggaagaagat atataacggt
     1561 tgaggaaggt caatatttaa tattaaatga ttgttattta attgaaaatg aatagatgta
     1621 attgtattta atagtaaatc atatatttta tttaaggaaa gg
//
LOCUS       DAFAZV010000153         1502 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFAZV010000153 DAFAZV010000000
VERSION     DAFAZV010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1502
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.165"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..1020
                     /locus_tag="KOU88_004161"
     CDS             <1..1020
                     /locus_tag="KOU88_004161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003439056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK3213948.1"
                     /translation="FDSIGLSIVMTLNSIKNMNDLLEDNLLKLELIMISKSLLIVLIP
                     LLKFIRLKTKINKRDCIYLSIPLIANIIGVIVIFEFIFKDKIIDSKESLIILTISTVF
                     LLSNLSLVSIIGRIIKDNSLKIEYEITKKRMNMQYKYYLNLQEYQLKIRKLYHDMNNH
                     IICIQNVYGKNEFADKYIKDINKQIKECNTIFNTQNMILDVILSDKKSICDMNSIYFL
                     VDINFLECNFIEMPDICSIFSNIIDNAIEACIKIKDTSIQKKIKLRGTVINRLFVIKC
                     ENTKINEVVLKNNKVITSKKDSFLHGIGISSVKSSVEKYNGNVEIYSDKNKFTITIYI
                     PLTRN"
BASE COUNT          654 a          107 c          220 g          521 t
ORIGIN      
        1 tttgatagta ttggattaag tatagtaatg acacttaatt ctataaaaaa tatgaatgat
       61 ttattagagg ataatttgtt gaagttagag ttaataatga tatctaaatc attactaata
      121 gtattaatac cattgcttaa gtttatcaga ttaaaaacaa aaataaacaa gagggattgt
      181 atatatttat ctattccatt aatagcaaac attattggtg taatagtaat atttgaattt
      241 atttttaaag ataagattat cgattctaaa gagagtttaa taatacttac aatatcaact
      301 gtatttttac tatcaaatct ttcattagta agcataatag gaagaataat aaaagataat
      361 agtttaaaga tagaatatga aattacaaaa aaaagaatga atatgcaata taaatattat
      421 ttaaatttac aggaatatca gttgaaaata agaaaactat atcatgatat gaataatcat
      481 atcatttgta ttcagaatgt ttatgggaaa aatgagtttg cagataagta tattaaagat
      541 ataaataagc aaataaaaga atgtaatact atatttaata ctcagaatat gattctagat
      601 gttattttaa gtgataaaaa atctatttgt gatatgaata gtatatattt tctagtagat
      661 attaattttt tagaatgtaa ttttatagag atgccagata tatgtagtat attttcaaat
      721 ataatagata atgcaataga agcttgtatt aagattaagg acacaagtat acaaaaaaag
      781 attaaattaa gaggaactgt tataaatagg ttatttgtaa taaaatgtga aaatacaaag
      841 ataaatgaag ttgtattaaa aaataataag gttattacaa gtaagaaaga ttccttttta
      901 catggaatag gaataagtag tgtaaaaagt tcagtagaaa aatataatgg aaatgtggaa
      961 atatactcag ataaaaacaa gtttacaatt actatttata taccattaac taggaactaa
     1021 ttctagttgg ggctctaaat tgcccagttg gagcagtagt attgaaagat aaaatagaag
     1081 atgctatctt taaggcatag gatatttgga ggtgataaaa atggttgaat gctatgctaa
     1141 taagataaca tcctttttag tactcaataa aataatagaa caaaaaatgt gatttatatt
     1201 tgtttgaatt taaaatgttg ataggtttta tagttatatt atttgcatga tatatcttaa
     1261 ataaatttag aaaaatagag ttatttttat ctgcaaatgc gaccttagta tggtaacatt
     1321 attgaccaaa agttctatat agtataaaaa aataaaatgt aaatttgata aactttataa
     1381 ctaggaacat aaaaacaaca attaaataac taattagata gtaaagttga tattagtaat
     1441 aaatattaaa gaaaaatatt ttactaattt gaggaggact tagttgtgat agattctgaa
     1501 ga
//
LOCUS       DAFAZV010000154         1472 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFAZV010000154 DAFAZV010000000
VERSION     DAFAZV010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1472
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.167"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..758
                     /locus_tag="KOU88_004162"
     CDS             <1..758
                     /locus_tag="KOU88_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003432175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3213949.1"
                     /translation="AKKMGQGDFKRTYFDFSDKELVELSTVMNKSAEYLDKYDNEQKI
                     FFQNASHELRTPLMSIKGYAEAIKYNVIDSKHASDIILEESDRLSDMVEDLLYISKID
                     NITKDFELVECDLREVLSNCGARQNVRAINKGIEFIYEFDEEMVLFECDEKNISKAFM
                     NLIENALRYAKSEIKIVCKYNQKNIVVIIEDDGIGIKKEDLPHVFERFYKGVGGNHGI
                     GLSIVKSIVNKHGGRIYVENGKKGAKFTILFKL"
     gene            complement(869..>1472)
                     /locus_tag="KOU88_004163"
     CDS             complement(869..>1472)
                     /locus_tag="KOU88_004163"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213950.1"
                     /translation="LNIGIKNKGSQYFMGISKCTSFLNRQIILQVNKKTILDKIVANT
                     LILLFSSIISKPSFTNKTKILVTTISDSIKNILNKTVVNNRVFKFPLYKNDVEKIRMK
                     IKGIVILGFKVIKLQNPKHIIKPSLAYLTTFIYPSFWPKKSDKNIWMTKASNTTVTKF
                     VILKISCSFIHIFYKIRSLLKPKYTSDFTFPFVSIFKHLL"
BASE COUNT          568 a          128 c          252 g          524 t
ORIGIN      
        1 ttgcaaaaaa aatgggtcaa ggagatttca aaagaaccta ctttgacttt tcagataaag
       61 aattagtaga gctctcaact gttatgaata agagtgctga gtatctggat aagtatgata
      121 atgaacaaaa aatatttttt caaaatgcat ctcatgaatt aaggacacca cttatgtcta
      181 ttaaaggtta tgcagaagct ataaaatata atgttataga tagtaaacat gcaagtgata
      241 taattcttga agaaagtgat aggttaagtg atatggttga agatttatta tacatttcta
      301 aaatagataa tataactaaa gattttgaac ttgtagaatg tgatttaaga gaagtacttt
      361 caaattgtgg agctaggcaa aatgtaagag ctataaataa ggggatagaa tttatttatg
      421 aatttgatga agaaatggtt ttatttgaat gtgatgaaaa aaacatttcc aaagcattta
      481 tgaatcttat agaaaatgct ttgagatacg ctaagagtga aataaaaata gtgtgtaagt
      541 ataatcaaaa aaatatagtt gtgataatag aagatgatgg aattggaatc aagaaagaag
      601 atttacctca tgtttttgaa agattctata agggagtagg aggaaatcat ggaattggat
      661 tatcaatagt taaatctatt gtaaataagc atggtgggcg tatatacgta gaaaatggca
      721 aaaaaggagc taaatttact atattattta aattgtaaaa aaattagaga aaatatagag
      781 atgtttgaag ttgtttttta tatatatctg ttgtatactg ttgaaaaaag aacaatatta
      841 agctgacata tattacgata gttgacattt aaagtaaatg cttaaatata gatacgaaag
      901 gaaaagtaaa atctgaagtg tatttaggtt taagtaagct tcttatttta taaaaaatat
      961 gtatgaaaga acagctgatt tttaatatta caaatttagt aacggttgta tttgaagctt
     1021 ttgtcatcca tatgttttta tcagactttt taggccagaa agaagggtat ataaaagttg
     1081 taagatatgc taaactgggt tttataatat gtttaggatt ctgtaattta ataactttaa
     1141 accctaaaat cacaatgcct ttaattttca tccttatttt ttcaacatca tttttatata
     1201 aaggaaattt aaagacacga ttgtttacta ctgttttatt aagtatattc tttatactgt
     1261 cagaaattgt agttacaagt atttttgttt tatttgtaaa agaaggcttt gaaataatgc
     1321 ttgaaaataa tagtataaga gtattggcga caattttatc taaaattgtc tttttgttga
     1381 cttgtaaaat tatttgtcta tttaaaaagg atgtacattt agatatgccc ataaagtatt
     1441 ggctcccttt atttttaata cctatattta gt
//
LOCUS       DAFAZV010000155         1448 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFAZV010000155 DAFAZV010000000
VERSION     DAFAZV010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1448
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.168"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..>1448
                     /locus_tag="KOU88_004164"
     CDS             <1..>1448
                     /locus_tag="KOU88_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213951.1"
                     /translation="IIKANSNNLWGVNGLAYQLGKINLEFFCMYFMQDTYLPKEDNAA
                     APIAKVHHELWEDIQESIIGDGSQQLGRIYPRGTGKSAFGDLATTVWSHCYKHKTYTL
                     ICSDIGSTAEKFVKDIKNALLENEYIKKAFGVLLNDNDRKYICNSTQLELTNKTFIEA
                     ISSSSPMRGRKYNNNRPDLIILDDYQSEENVRTEDAREKKFKRFSDDVKYAAQKPVIR
                     NGKTIKRGTTFIALGTLQHKECFYSRLKNLPTWKFKCEKGVLVDNVDELFNSGLWLKF
                     KEILFDFKNTNHLEDAKEFYWENEKEMKFPILWPSFWDCLDMALSYYENPTSFKQEVQ
                     NDVNSIGEKWFKTVRTETREEIESHTFKKTMLLCDPASAGGSKHDYSAFLVGSESENG
                     LLYGRLAELAKINARTDFDKYIDHMIYLLKVYSDITHIYIEKNTFNGADANQLEFKIK
                     NDNVLSYRDIEIINEQQKKNKDDKISTLIPVL"
BASE COUNT          583 a          175 c          250 g          440 t
ORIGIN      
        1 attataaaag ccaattcaaa caatctttgg ggagttaatg gtctcgctta tcaacttgga
       61 aaaataaacc tagaattttt ctgtatgtat tttatgcaag acacatattt accaaaagaa
      121 gataatgctg ctgctcctat agctaaagtt catcatgagc tatgggaaga tatacaagaa
      181 tctataattg gagatggttc acagcaatta ggaagaattt atccaagagg gacaggtaaa
      241 agtgcatttg gagatttagc gacaactgta tggtcgcatt gctataaaca taagacatat
      301 actttgattt gctctgacat aggatctaca gcagagaaat ttgtaaaaga tataaaaaat
      361 gcattacttg aaaatgagta tattaaaaaa gcatttggtg tccttttaaa tgataatgat
      421 agaaaataca tttgtaatag tactcaacta gagctaacaa ataaaacttt tattgaagct
      481 atatcatctt catcacccat gagaggaaga aaatacaata ataaccgtcc agatcttatc
      541 atacttgatg attatcagtc agaagaaaat gttagaacag aagatgctag agagaaaaaa
      601 tttaaaagat tttctgatga tgtaaaatat gctgctcaaa aaccagtcat aagaaatggt
      661 aaaactataa aaagaggaac aacttttata gcattaggaa ccttacaaca caaagaatgt
      721 ttttatagta gactaaaaaa tttaccaact tggaagttta aatgcgaaaa aggagtttta
      781 gttgataatg tagatgaatt atttaattct ggtttatggc ttaagttcaa agagatctta
      841 tttgatttta aaaatacaaa tcatcttgaa gatgctaaag aattttactg ggaaaatgaa
      901 aaagaaatga aattccctat attatggcca agtttttggg attgtttaga tatggctcta
      961 agttattatg aaaatccaac atcttttaag caggaagtgc aaaatgatgt caattctata
     1021 ggagaaaaat ggtttaaaac tgttagaaca gaaactagag aagaaattga atcgcatact
     1081 tttaaaaaga caatgctgtt atgtgatcca gcatctgcgg gtgggtcgaa acatgactat
     1141 agcgcttttc ttgttggaag tgaatcagaa aatggtttac tatatggaag attggcagaa
     1201 ctagctaaaa taaatgctag aactgatttt gataaatata tagaccatat gatttattta
     1261 ttaaaagtgt attcagatat aacacatatt tatatagaaa aaaatacatt taatggcgca
     1321 gatgccaacc aattagagtt taaaataaaa aatgataatg ttcttagtta tagagatata
     1381 gaaatcatta atgagcaaca aaagaaaaat aaagatgata aaatctctac tttaatacct
     1441 gttttaag
//
LOCUS       DAFAZV010000156         1426 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFAZV010000156 DAFAZV010000000
VERSION     DAFAZV010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.169"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..698
                     /locus_tag="KOU88_004165"
     CDS             <1..698
                     /locus_tag="KOU88_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009274549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3213952.1"
                     /translation="IAGGTGGGKTYFLLTLIEALLYTNAVLYILDPKNSDLADLGTVM
                     GNVYHTKEEMIDCVNAFYEGMVQRSEEMKQHPNYKTGENYAYLGLPPCFLIFDEYVAF
                     FEMLGTKESVSLLSQLKKIVMLGRQAGYFLIVACQRPDAKYFSDGIRDNFNFRVGLGR
                     ISELGYGMLFGSDVKKQFFQKRIKGRGYCDVGTSVISEFYTPLVPKGHDFLQTIGRLA
                     QERQVMPEQQEKE"
     gene            709..1113
                     /locus_tag="KOU88_004166"
     CDS             709..1113
                     /locus_tag="KOU88_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009269732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213953.1"
                     /translation="MGYLQMQLIDETTDKNTKGICLNIDKFFTDLDFTANSDFEKWDE
                     YPFERYHEKMSKVLENIEHKQQELPLLFSIPLDKEMSFLEITFYYNFIVMDKVLFQHM
                     QHEYEFDKEALELCENEDMDCIVLYMGMNVRE"
     gene            1346..>1426
                     /locus_tag="KOU88_004167"
     CDS             1346..>1426
                     /locus_tag="KOU88_004167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003062030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBK3213954.1"
                     /translation="MVLNEEQWIKELREKRVAYGISQGRLA"
BASE COUNT          459 a          250 c          344 g          373 t
ORIGIN      
        1 tgattgctgg tggtacgggt ggtggtaaga cctattttct gctgacactc attgaagcct
       61 tactgtatac caacgctgtc ctttatatct tagacccaaa gaatagcgac cttgcagact
      121 tgggaacagt tatgggaaat gtttaccata ccaaagaaga aatgattgat tgcgtcaatg
      181 ccttttatga gggaatggta cagcgaagcg aggaaatgaa gcaacacccg aactataaga
      241 cgggcgaaaa ctacgcctat ctgggactgc caccctgctt tcttattttt gatgaatatg
      301 tggcattttt tgaaatgctg gggacaaagg aaagcgtgag cctacttagc cagctaaaga
      361 aaatcgtcat gttagggcga caagcaggat atttccttat tgttgcttgc cagcgtccag
      421 acgcaaagta tttctcggac ggtatcagag ataacttcaa tttccgtgtg ggattggggc
      481 gtatcagcga attaggttac ggtatgctgt ttggttcaga tgtgaaaaag cagttttttc
      541 agaagcgtat caaggggcgt ggctattgtg acgtgggaac aagtgtcata agtgaatttt
      601 acacgccttt agtcccgaaa ggacacgatt ttttacaaac gattggcagg cttgcacaag
      661 aaagacaagt tatgccagaa caacaggaaa aggagtgaaa caataactat gggttattta
      721 caaatgcaac taatagatga aacaacagat aaaaatacaa agggtatctg tttgaatatt
      781 gataaatttt ttaccgattt agacttcacg gcaaacagcg attttgaaaa gtgggacgaa
      841 tacccttttg aacgttacca cgagaaaatg agtaaagtgt tggaaaatat cgaacataaa
      901 cagcaggaat taccgttgtt attttctatt ccgctggaca aagaaatgtc attcttggaa
      961 atcacatttt actacaactt tattgtcatg gataaggtcc tgtttcaaca tatgcaacat
     1021 gagtatgagt ttgacaaaga agcactagaa ctatgcgaaa atgaagatat ggactgcatt
     1081 gtattgtata tgggtatgaa tgtacgtgaa taagtaaccg aaacggcagg aacggtcagc
     1141 gaagcgaccc agaccgtgta tgccgttgct ggtgtggcgt cagccacgcc agcagataaa
     1201 acccctcggt atctaacaga ggggtacgtt tgcaaataga caatagacaa aaaacatagg
     1261 aaacataagg cttctggcat gatttcctag caaaaatcgg ttgtgaagtc gccttaaaaa
     1321 acttcacact tgacagattg ggggtatggt tctgaatgaa gaacaatgga taaaagaatt
     1381 acgggagaaa cgggttgctt acggtatctc gcaaggcagg ctggcg
//
LOCUS       DAFAZV010000157         1381 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFAZV010000157 DAFAZV010000000
VERSION     DAFAZV010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.170"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..>1381
                     /locus_tag="KOU88_004168"
     CDS             <1..>1381
                     /locus_tag="KOU88_004168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK3213955.1"
                     /translation="QEAYKLDFINDMADSIGKSIQTLAGVTANGFSSSGFYVGFLLLI
                     ILVVGLYVAYTGLIKRETSKALHAVINFVVVFLLSASFIAYAPDYIKKINEFSSDIST
                     ASLDLGTKIMLPNSDSEGKDSVDLIQDSLFSIQVEQPWLLLQFGNSNAEEIGTDRVEA
                     LVSASPEDEDGKTREEVVKTEIEDNDNNNLTIPQVVNRLGMVFFLLFFNLGITIFVFL
                     LTGMMLFSQILFIIFAMFLPISFLLSMIPSYESMAKQAIVRVFNTIMTRAGITLIVTV
                     AFSISSMFYNISTDYPFFMVAFLQIVCFAGIYMKLGDLMSMFSLNAGDSQSMGRRIFR
                     RPYLYLAHRARRMERRLAGAVAGSTISNRKPTRNTATKDSRGNTTSSMGQRAGSKVGA
                     VLDTKNKVKDKANAVKENIKDMSTQTAYAVYSAKEKAKSSVSDFKRGMVQEQQSRQTG
                     RLEGREQHR"
BASE COUNT          402 a          282 c          336 g          361 t
ORIGIN      
        1 tgcaagaagc ctataaactg gacttcatta acgatatggc agatagtatc ggaaagagca
       61 tacagaccct tgcaggtgtt acggcaaacg gtttttccag ctctggcttc tatgttggtt
      121 ttctgcttct cattatctta gtggtgggac tttatgttgc ctatacggga ctgataaaac
      181 gggaaacaag caaagcactt cacgctgtta ttaactttgt tgtggtgttc ttgctgtctg
      241 cttcgtttat cgcctatgct cccgactaca tcaagaagat aaatgaattt tcatcagaca
      301 tcagtaccgc ttcacttgat ttgggaacaa aaatcatgct ccctaactct gacagcgagg
      361 gcaaggacag cgtggacttg atacaggaca gcttattttc tattcaagtg gaacagccgt
      421 ggctacttct gcaatttggc aacagcaacg cagaggaaat cggaacagac cgtgtcgaag
      481 ctctcgtatc ggcaagccca gaggacgagg acgggaaaac cagagaggaa gtcgtgaaaa
      541 cagaaatcga ggacaacgac aacaacaatc tgacaatacc gcaggtcgtg aaccgtttag
      601 gtatggtgtt cttcctcttg ttctttaact tgggtatcac gatatttgta ttcttgctta
      661 cgggcatgat gttattcagc cagatacttt ttattatctt tgcaatgttt ttacctatca
      721 gttttctact ttccatgata ccgagctatg aaagcatggc aaagcaggca atcgtaaggg
      781 tatttaatac cataatgaca cgggcaggaa taacgcttat tgtaacggtg gcgttcagca
      841 tttccagtat gttttataac atttccacag attatccgtt tttcatggtg gcgttcttgc
      901 agatagtatg tttcgctggt atttatatga agctgggcga cttaatgagt atgttctcac
      961 ttaatgctgg cgatagtcaa agtatgggac gcaggatatt ccgcagacca tatctatact
     1021 tggcacatag ggctagacgt atggaaagac ggcttgctgg tgcggtggca ggtagcacga
     1081 tttcaaacag aaaaccgaca aggaacacag ctacaaaaga cagtcggggc aataccactt
     1141 ccagcatggg acagcgtgca ggctcaaagg tgggtgctgt cttagataca aaaaataaag
     1201 tgaaagataa ggcaaacgct gtcaaagaaa acatcaagga tatgtcgaca cagactgctt
     1261 atgcggtgta ttccgcaaag gaaaaagcaa agtccagcgt gtccgacttc aagcgtggca
     1321 tggtgcagga acagcagtcc agacaaacgg gacgcttgga agggcgggaa cagcatagac
     1381 a
//
LOCUS       DAFAZV010000158         1337 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFAZV010000158 DAFAZV010000000
VERSION     DAFAZV010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1337
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.172"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            27..101
                     /locus_tag="KOU88_004169"
     tRNA            27..101
                     /locus_tag="KOU88_004169"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:59..61,aa:Thr,seq:tgt)
     gene            116..200
                     /locus_tag="KOU88_004170"
     tRNA            116..200
                     /locus_tag="KOU88_004170"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:150..152,aa:Tyr,seq:gta)
     gene            210..293
                     /locus_tag="KOU88_004171"
     tRNA            210..293
                     /locus_tag="KOU88_004171"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:244..246,aa:Leu,seq:tag)
     gene            323..399
                     /locus_tag="KOU88_004172"
     tRNA            323..399
                     /locus_tag="KOU88_004172"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:357..359,aa:Arg,seq:tct)
     gene            407..482
                     /locus_tag="KOU88_004173"
     tRNA            407..482
                     /locus_tag="KOU88_004173"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:440..442,aa:Gln,seq:ttg)
     gene            571..659
                     /locus_tag="KOU88_004174"
     tRNA            571..659
                     /locus_tag="KOU88_004174"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:605..607,aa:Ser,seq:tga)
     gene            663..738
                     /locus_tag="KOU88_004175"
     tRNA            663..738
                     /locus_tag="KOU88_004175"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:696..698,aa:Phe,seq:gaa)
     gene            745..818
                     /locus_tag="KOU88_004176"
     tRNA            745..818
                     /locus_tag="KOU88_004176"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:779..781,aa:Met,seq:cat)
     gene            833..909
                     /locus_tag="KOU88_004177"
     tRNA            833..909
                     /locus_tag="KOU88_004177"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:867..869,aa:Ile,seq:cat)
     gene            933..1009
                     /locus_tag="KOU88_004178"
     tRNA            933..1009
                     /locus_tag="KOU88_004178"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:967..969,aa:Pro,seq:tgg)
     gene            1017..1093
                     /locus_tag="KOU88_004179"
     tRNA            1017..1093
                     /locus_tag="KOU88_004179"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1051..1053,aa:His,seq:gtg)
     gene            1102..1177
                     /locus_tag="KOU88_004180"
     tRNA            1102..1177
                     /locus_tag="KOU88_004180"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1135..1137,aa:Lys,seq:ttt)
     gene            1185..1258
                     /locus_tag="KOU88_004181"
     tRNA            1185..1258
                     /locus_tag="KOU88_004181"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1217..1219,aa:Cys,seq:gca)
     gene            1265..1336
                     /locus_tag="KOU88_004182"
     tRNA            1265..1336
                     /locus_tag="KOU88_004182"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1297..1299,aa:Asn,seq:gtt)
BASE COUNT          321 a          309 c          355 g          352 t
ORIGIN      
        1 ccccttccag gtcgccaaaa taaaatgctg gtgtggctca acggtagagc agctgacttg
       61 taatcagcag gttgtaggtt cgattcctat caccagctcc atgtaaaatt aatacggagg
      121 atttcccgag cggccaaagg gggcagactg taaatctgtt gtcatcgact tcggtggttc
      181 gaatccacca tcctccacca aaaaaatgcg cggatgtggc ggaattggca gacgcactag
      241 acttaggatc tagcgccatt ggcgtggggg ttcgactccc ttcatccgca ccatttttgt
      301 ttgatataca tatataaatt gtgggtgcat agctcagctg gatagagcaa cgcccttcta
      361 aggcgtgtgt ccggggttcg aatccctgtg cgctcaccac atatattggg gattagccaa
      421 gtcggtaagg cacatgactt tgactcatgt atgcgtaggt tcgagtcctg catccccagc
      481 caaatgatgt attactaagc tatatttgaa ttatttttat tttaaatata gttaggttca
      541 attttagaat aagtttaagt atccgaatgt ggagaggtgt ccgagtggtt taaggagctg
      601 gtcttgaaaa ccagtgactt cgaaaggggc cgtgggttcg aatcccaccc tctccgccaa
      661 atgcccagat agctcagtcg gtagagcagg ggactgaaaa tccccgtgtc ggtggttcga
      721 ttccgcctct gggcaccaaa atatggcggt atagcttagt tggctagagc gttcggttca
      781 tacccgaaag gtcataggtt cgactcctat taccgctact aaaatttaat gtgggccatt
      841 agctcagttg gttagagcgc ccggctcata accggtaggt ctggggttcg agtccctgat
      901 ggcccaccac attaaattaa ttaatataaa ttcgaggtgt agcgcagttt ggtagcgcac
      961 atggtttggg accatggggc cgggggttcg agtcccttca cctcgaccaa tataaggtgg
     1021 gtatagctca gttggttaga gcgccagatt gtggctctgg aggtcgtgag ttcgactctc
     1081 attatccacc ccaattcata tggtctatta gctcagtcgg tagagcacct gacttttaat
     1141 cagggtgtcc cgcgttcgag tcgcggatag atcaccaaaa aggtggcgac atagccaagt
     1201 ggtaaggcag tggactgcaa ctccttgatc cccagttcga atctgggtgt cgcctccaaa
     1261 atattccaag gtagctcaac ggtggagcaa ccggctgtta accggtaggc tgtgggttcg
     1321 agccccaccc ttggagc
//
LOCUS       DAFAZV010000159         1309 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFAZV010000159 DAFAZV010000000
VERSION     DAFAZV010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1309
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.173"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..1044
                     /locus_tag="KOU88_004183"
     CDS             <1..1044
                     /locus_tag="KOU88_004183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK3213956.1"
                     /translation="HTFENNSHFMDLTLVDGDEFASYSSSSYSSGNTNNKDEKKNGPA
                     QSTTSKEDNDMINKLNKVFKNKLSNTGSIFVKYSNAYKVNAALMAAISIHETGNGSSS
                     LCKNKNNFFGMKGMSFGSVDEGIKRGISNLSRNYIHMGRKTLESIRDKYAPLYDSPLN
                     KHWVPGVNKFYKQITGNAYSSNSAGTGVRSNEEAEKNLKDITYQVQNSNNANTSTNNN
                     SKVNKVIQEAKNQLGKPYKWGGNGPKSFDCSGLMVWAFKRGAGINLKRVSADQSNDSR
                     GKLLCNINDVKAGDLVFFAYNQGKGNVHHVGLCIGNDKFIHSPNTGDVVKISSLSGRQ
                     KQKHDFARARRFF"
     gene            1058..>1309
                     /locus_tag="KOU88_004184"
     CDS             1058..>1309
                     /locus_tag="KOU88_004184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2577 domain-containing protein"
                     /protein_id="HBK3213957.1"
                     /translation="MSQDLLQIIKKAAMDAVETSNPMQIAFGTIESVNPLVVKIEQKA
                     SFEESFLIQTDTFKRYTDKKIGDKLVLIRMQGGQQYLILD"
BASE COUNT          539 a          157 c          244 g          369 t
ORIGIN      
        1 cacacatttg aaaataattc gcactttatg gatttgactc ttgttgatgg agatgaattt
       61 gcttcttatt cttcaagctc atatagtagt ggaaatacta ataataaaga tgaaaagaaa
      121 aatggtcctg cacaaagtac tacaagtaaa gaagacaatg atatgataaa taaattaaat
      181 aaagtattta aaaataagtt atcaaataca ggaagtatat ttgttaaata ttctaatgct
      241 tacaaagtca atgcagcttt aatggctgct atttctatac atgaaactgg taatggaagt
      301 tcttcacttt gtaaaaataa aaataatttc tttggaatga aaggaatgtc ttttggctct
      361 gtggatgaag gaataaaaag aggtataagt aatttatcaa gaaactatat ccatatggga
      421 agaaaaacat tagaaagtat tagagacaaa tatgctccac tttatgatag tcctcttaat
      481 aaacattggg taccaggagt aaataagttt tataaacaaa taacgggaaa tgcatatagt
      541 tctaatagtg caggtacagg tgttagaagc aacgaggaag cagaaaagaa tttaaaagat
      601 ataacttatc aagttcaaaa tagcaacaat gctaatacat caacaaacaa taatagtaaa
      661 gtaaataaag ttattcaaga agcaaaaaat caacttggca agccttacaa atggggtggt
      721 aatggtccaa agagttttga ctgtagtggt cttatggtgt gggcattcaa aagaggtgca
      781 ggtataaatc tcaaaagagt ttcagcagac caatcaaatg atagtagagg aaaactatta
      841 tgcaacataa atgatgtaaa agctggcgat ttagtattct ttgcatacaa ccaaggaaaa
      901 ggaaatgtac atcacgttgg actatgtata ggaaatgaca agttcataca ttcaccaaat
      961 actggtgatg tagttaaaat aagcagttta agtggtagac aaaaacaaaa acatgatttt
     1021 gcaagagcta gaagattctt ttaagtgagg tgataatatg agccaagatt tattacaaat
     1081 aataaagaaa gctgcaatgg atgcagtaga aacaagcaac ccaatgcaga ttgcatttgg
     1141 aactatagaa agtgttaatc ctttagtagt taagatagag caaaaagcct cttttgaaga
     1201 atcttttcta atacaaacag atacatttaa aagatataca gataaaaaga taggagataa
     1261 attagtctta attaggatgc aaggaggaca gcaatatttg attttagat
//
LOCUS       DAFAZV010000160         1182 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFAZV010000160 DAFAZV010000000
VERSION     DAFAZV010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1182
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.175"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            126..275
                     /locus_tag="KOU88_004185"
     CDS             126..275
                     /locus_tag="KOU88_004185"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213958.1"
                     /translation="MEIVAVYYIAKFLLDLYKVKSHSKSEAKSGFIFNLTINKLIVKI
                     KYKKY"
     gene            812..>1182
                     /locus_tag="KOU88_004186"
     CDS             812..>1182
                     /locus_tag="KOU88_004186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaI/MecI/CopY family transcriptional regulator"
                     /protein_id="HBK3213959.1"
                     /translation="MKEEILIEKLLRAELIVMEYLWKKDTLMPKKEIVKEIKQIYGWH
                     KSTIKILLKRLIDKGYLARDIIKFQSYYKIIIDNEEYYAFKKKVLKSSKSRKIMRSLT
                     TTHKNVSKEKLDSLEEYYKNL"
BASE COUNT          497 a          124 c          161 g          400 t
ORIGIN      
        1 tggagaatgg atatttgata attgtaaaat tatgttataa tttatatgta aggaactaaa
       61 tatctaagag tggcagtttc cacattatgc tctaacctac tttctaatga aaggaggtgg
      121 gaagtgtgga aatagtagca gtttattaca tagcaaaatt tttacttgat ttatacaaag
      181 taaaaagcca ctcaaagtcg gaagctaaga gtggctttat atttaattta actattaata
      241 aactaatagt aaaaattaaa tataaaaagt actaaatttt ttcggaaact acactctcga
      301 caatagatta tagttcctta tttctaaaga ggtaggagaa ttgcagttct cttatctctt
      361 tttgatacga atttacatct ttattatatc gcattttgag aaaaaataaa actatgaata
      421 ttagaaatat attttatttt atctctaagt atatatatta ttagccacct aaaaaacttt
      481 cacaaaaaca aaaagagtat atgtttttga taactggatg atataactta taactcattt
      541 tacaattctt agttcatata tatttatgcc actaaatttc tctagttttg ccgatttagt
      601 tttattctac aactaaaata atacaataga attagttatt attcaacaag attgtttgaa
      661 agttaaataa atttatagat atgaacatta ttttacactt aaaaaaacag actaaatatg
      721 tagaatattt ggtaaaactt acctctagtt tttgtcttaa aaagctccta ttattaattt
      781 aagttagacg aatttaagga agtgacataa attgaaagaa gaaatattaa tagaaaaatt
      841 attaagagca gaattaatag taatggagta tttatggaaa aaggacactc taatgcctaa
      901 aaaagaaatt gtaaaagaaa taaaacagat ttatggatgg cataaaagta caataaaaat
      961 actactaaaa aggctaattg acaaaggtta tttggctagg gatattataa aatttcaatc
     1021 ttattataaa ataataatag ataatgaaga atattatgct tttaagaaaa aggtactaaa
     1081 atctagtaaa agtagaaaaa taatgcgttc acttaccact acgcataaaa atgtaagtaa
     1141 agagaagtta gactcattag aagagtacta taaaaactta aa
//
LOCUS       DAFAZV010000161         1176 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFAZV010000161 DAFAZV010000000
VERSION     DAFAZV010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1176
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.176"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(262..972)
                     /locus_tag="KOU88_004187"
     CDS             complement(262..972)
                     /locus_tag="KOU88_004187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009895627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213960.1"
                     /translation="MTSICICDDEKQQRNMLNKIITREMDLWGYPYQIKEYSNGESLV
                     YNLEHENYYIDIIFLDIELGKSNGVDIAKTIRKHSKDTIIIFVTGFSDYVFHGYDVGA
                     LNYILKPYKTEKICKVLKEALKKLEQWKENFITVQIGTNLCKINTKDILYFKSELRKL
                     TVVTFDKTLEYYGKLNDMETVLPSNFIRTHQRYIVNLNHVDSITQTYAKVQNEKIPIS
                     RKKYQEVVGKFTRYMLES"
BASE COUNT          431 a          155 c          128 g          462 t
ORIGIN      
        1 aaaaaattaa gtttgaaaaa actctaaaaa ctaagcttca aaaaattaaa ttttgaaaga
       61 ttgaaattct agaaactgag ctttaaaaaa ttaagtttga aaaaaactct aaaaactaag
      121 cttcaaaaaa ttaaattttg aaagattgaa attctagaaa ttaagcttca aaaaattaaa
      181 tttgaaaaaa caaaactcta aaaactaagc tttaaaaagt taagtttcaa aaataaaatt
      241 ctagagattg aacttcaaaa attaagattc taacatatac cttgtaaatt ttcctacaac
      301 ctcttgatat tttttacggc ttataggaat tttttcattc tgaactttgg cataagtttg
      361 agttatacta tctacatggt ttagattgac aatatacctt tgatgcgtac gtataaaatt
      421 agagggaaga acagtttcca tatcatttaa ttttccgtag tattctaatg ttttatcaaa
      481 ggtaactaca gttaattttc ttagctcact tttaaagtag aggatatctt ttgtattaat
      541 tttacaaaga ttagttccaa tctgaactgt aataaagttt tctttccatt gttctaattt
      601 ttttagtgct tcttttaata ctttacatat tttttcagtt ttataaggtt ttaagatgta
      661 gttcaaagct cctacatcat atccatgaaa tacatagtca gaaaaacctg tgacaaagat
      721 gattatagta tcttttgaat gttttcgtat agtttttgct atgtcaacgc cattactttt
      781 tccaagttca atatctaaaa aaataatatc tatgtaataa ttttcgtgtt ctagattgta
      841 tactagactt tctccatttg aatattcttt tatttggtag gggtagcccc acaaatccat
      901 ttctcttgta atgattttat tcagcatgtt tctttgttgt ttttcatcat cacaaataca
      961 aatcgaagtc aattttttat ctcctttcaa attttatatt tatatagtta agtatataat
     1021 atattttgct acctagatat ataaaatgaa ataacaatta tatccagata gcaaaataaa
     1081 attttttata ttagtatact tacacttaaa actattctat taaacttatt ctgaagtgct
     1141 aatgattttc ttattaaaaa atctaacaat ctttct
//
LOCUS       DAFAZV010000162         1176 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFAZV010000162 DAFAZV010000000
VERSION     DAFAZV010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1176
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.177"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..695
                     /locus_tag="KOU88_004188"
     CDS             <1..695
                     /locus_tag="KOU88_004188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBK3213961.1"
                     /translation="CETTGPVFELGQLIPIEYVDKLETAELTEILINGEDEESEDSLR
                     QRYYDSLNSQSFGGNMQNYKDEVNKIQDVGGVKVYPVWDGGGTVKLVIINSNFKVPSE
                     NLVNLVQEEIDPLQNQGEGIGLAPIGHRVTVEGVTSTTINISAEITYKNGYTWENIKS
                     IAEEAIDDYLNELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINEVKSNLTIN
                     SNSIVVRGEVVG"
     gene            688..>1176
                     /locus_tag="KOU88_004189"
     CDS             688..>1176
                     /locus_tag="KOU88_004189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBK3213962.1"
                     /translation="MDKEINLINYLPHILQDKEEYIKVFNVENKEIKTLYDKLKDLSN
                     NQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNF"
BASE COUNT          485 a          127 c          224 g          340 t
ORIGIN      
        1 aatgtgaaac tactggacct gtatttgaac ttggtcagtt gattccaatt gaatatgtag
       61 acaaattaga aactgctgag ttaactgaaa tactaattaa tggagaagat gaagaaagtg
      121 aagatagttt aagacaaaga tattatgata gcctaaactc acagagtttt ggtggaaata
      181 tgcaaaatta taaagatgaa gttaacaaaa tacaagatgt tggaggagtt aaggtttatc
      241 ctgtgtggga cggtggaggt actgttaagt tagtaataat taattctaac ttcaaagttc
      301 catcagagaa tttagttaat ttagttcaag aagaaattga tcctctacaa aaccaaggag
      361 aaggtattgg attagcacca attggacacc gagtcacagt tgaaggagtt acaagtacaa
      421 ctataaatat atcagcagag ataacataca aaaatggcta cacttgggag aatataaaat
      481 caattgcaga agaagcaata gacgactatt taaatgaact taacatgagt tgggaagatg
      541 aagaaaactt aatagtccgt atatctcaaa ttgaaactag attacttagt attgatggag
      601 tattagacat tgcaaataca atgataaatg aggttaaatc taatctaaca ataaatagta
      661 acagtatagt agtgagaggt gaggtagttg gataaagaga ttaatctaat aaattactta
      721 ccacacattc tacaagataa agaagaatat ataaaagtat ttaatgtaga aaataaagaa
      781 ataaaaacat tatatgataa attaaaggac ctatcaaata accagttttt agaggaccta
      841 actataagtg gtataaaaag atgggaaaag ataatgtcta taactcctaa aagtaatgag
      901 agtttagaag atagaaggtt taggattttt agtaaatata taagtaaact accttactca
      961 gagagatttt taaggaactg gctagataat gtagttggag aaggcaatta tgaattaact
     1021 attaataatg ctacttataa catacatctt gaaagtgatg ctagaaatca agattggttt
     1081 gaggaagttc attcttttgt aagtaatatt aagccatgta acatgacact ggattacact
     1141 agagtgctta taagcaaaga caattatatg aatttt
//
LOCUS       DAFAZV010000163         1173 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFAZV010000163 DAFAZV010000000
VERSION     DAFAZV010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1173)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1173)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1173
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.178"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..>1173)
                     /locus_tag="KOU88_004190"
     CDS             complement(<1..>1173)
                     /locus_tag="KOU88_004190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3213963.1"
                     /translation="LIKPTRCLIEEKQRYLKITYEDSESFVAYFTIESIIGEMDFPSS
                     EIFYYQQQQFTFPIDTSMNVEIVTNKKALTTVRNKKKELKDLDNHAWQAGNETGTNVV
                     EALDAVNELENNLDQTKESMYKLSYVIRVSADSIDELKRRCDEVKDFYDDLNVKLVRP
                     MGDMIGFHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQQLGENEGIYIGYSLDTGR
                     NVYLKPSLASQGVKGSVTNALAAAFLGSLGGGKSFANNLIVYYAVLFGGQAVLVDPKA
                     ERGNWKEDLPEIAHEINIVNLTSDIENKGMLDPYVIMKEVKDSESLAIDILTFLTGIS
                     SRDGEKFPILRKAIRNVTQSKCRGLLKVIDELRKDNSQISNNIADHIESFTDYDFAQ"
BASE COUNT          357 a          232 c          125 g          459 t
ORIGIN      
        1 ttgtgcaaaa tcataatctg taaaactttc aatatgatct gcaatgttat ttgatatttg
       61 agaattatct ttccttagtt catctattac ttttaaaagt cctctgcatt tactctgagt
      121 aacatttctt attgcttttc taagtatagg aaacttctct ccatcacgac tacttattcc
      181 tgtaagaaaa gttaatatat caatagctaa actttcacta tcttttactt ctttcataat
      241 tacatatgga tctaacattc ctttattttc tatatcactt gttaaattaa caatatttat
      301 ttcatgagct atctctggta ggtcttcctt ccaattacca cgttcagctt ttggatctac
      361 caaaacagct tgtcctccaa acaatactgc atagtaaaca attaaattat tagcaaatga
      421 ctttccccct cctaaagatc caagaaatgc tgctgctaat gcattagtta cagaaccttt
      481 tactccttga cttgcaaggg atggtttcag atatacgttt cttcctgtat ctaaactata
      541 tccaatatat attccttcat tttctccaag ttgttgagtt gctccaaacc ctaatccagc
      601 taaaaaatca ctagttacat attgaatata atcatttata tatcttttgc ttgaaggtat
      661 aaattcattg tgaaatccta tcatatctcc catgggacgt actaacttta catttagatc
      721 atcataaaaa tccttaactt catcacaacg gcgttttaat tcatcaatgc tatctgccga
      781 tactctaatt acataactta acttatacat cgattctttt gtttgatcta aattattttc
      841 aagctcattt acagcatcta atgcttctac tacatttgtt ccggtttcat ttcctgcctg
      901 ccaagcatga ttatctaaat cttttaattc ttttttctta tttctaactg tagttaaagc
      961 ctttttattt gttacaattt ccacattcat actagtatca attggaaatg taaactgttg
     1021 ttgctgataa taaaatatct cactagatgg aaaatccatt tctccaataa tactttcaat
     1081 agtaaaataa gctacaaaac tttctgaatc ctcatatgta atttttaggt atctttgctt
     1141 ctcttctata agacacctag ttggctttat aag
//
LOCUS       DAFAZV010000164         1155 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFAZV010000164 DAFAZV010000000
VERSION     DAFAZV010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1155
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.180"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(211..534)
                     /locus_tag="KOU88_004191"
     CDS             complement(211..534)
                     /locus_tag="KOU88_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213964.1"
                     /translation="MLNINEEKIEKLKQKQKINNLDTSQKTQDNDITDLMLATAEICE
                     MILSSQQTSTMSLKNIKLNEGGSSMAAIYVGLIERGLKTIDQVPVKYREEVRKMCEAL
                     EISLS"
     gene            complement(546..>1155)
                     /locus_tag="KOU88_004192"
     CDS             complement(546..>1155)
                     /locus_tag="KOU88_004192"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="chromosome condensation regulator"
                     /protein_id="HBK3213965.1"
                     /translation="IAGIKLKVNDSNNEIDKIEMYLNNELIHSKNEFINNFVLFTIPL
                     EKLNLGINNIYFKANTLFGDNMYLGATINKENNSINISEGANLFIKNKKYNINSLTNS
                     ADGKLVITLDRALEDNISVGDIIYQLINQLKVQVKTNNTGMHKDMNLLEMKKVDTGYQ
                     EIYELEEKGMTQAEPKIIVEKGDNWTAIKRPSMIFSIDETTL"
BASE COUNT          332 a          187 c          109 g          527 t
ORIGIN      
        1 gctataagtt ggtcgatttt agtatttaac tctgttttag cagtttctat atttgtatta
       61 acttttccaa tttcactatt agtgtcacta ggtacattct ttaatttttt tactacgtct
      121 tcatttaaca atttatcacc ttctttttta tttagagagc tacattagta actctctatt
      181 ttgaacataa aaaaaagaac tcttatagtt ctatgataat gaaatctcta gtgcttcaca
      241 catttttctt acctcttctc tatatttcac aggtacttgg tcaattgttt ttaaacctct
      301 ttctattaat cctacataaa ttgctgccat actacttcct ccttcattta attttatatt
      361 ttttaatgac atagtagatg tctgttgact acttaatatc atttcacata tttcagcagt
      421 cgctaacatt aaatctgtta tgtcattatc ttgcgttttt tgacttgtat ccaaattatt
      481 tattttttgt ttttgtttga gtttttcaat tttttcttca tttatattta acatttaatc
      541 acctcttaaa gcgtagtctc atctatagaa aatatcatag atggtctttt tattgcagtc
      601 caattatcac ctttttcaac tatgatttta ggctctgctt gtgtcattcc tttttcttcc
      661 aactcataaa tttcttgata tcctgtatca acttttttca tttctaataa attcatatct
      721 ttatgcatac ctgtgttatt tgttttaact tgaaccttta gttgatttat aagttgataa
      781 attatatctc ctacgcttat attatcttct aatgctctat ctaatgttat tacaagctta
      841 ccatctgcac tatttgttaa agaatttatg ttatactttt tattcttaat aaatagatta
      901 gccccttctg aaatatttat agaattattc tctttattaa ttgttgctcc tagatacata
      961 ttatctccaa ataaagtatt agctttaaag tatatattat ttataccaag attcaatttt
     1021 tcaagcggaa tagtgaacag cacaaaatta ttgataaatt cattctttga atgtattaat
     1081 tcattgttta aatacatttc aattttatca atttcattat ttgaatcatt aacttttaat
     1141 tttataccag ctata
//
LOCUS       DAFAZV010000165         1143 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFAZV010000165 DAFAZV010000000
VERSION     DAFAZV010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.182"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..662
                     /locus_tag="KOU88_004193"
     CDS             <1..662
                     /locus_tag="KOU88_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBK3213966.1"
                     /translation="GQLIPIEYVDKLETAELTEILINGEDEESEDSLRQRYYDSLNSQ
                     SFGGNIQNYKDEVNKLPDVGGVKVYPVWNGGGTVKLVIINSNFKVPSTDLVNLVQEEI
                     DPNMKGEGLGLAPIGHRVTVEGVTSTTINISAEITYKSGYTWENIKSIAEEAIDDYLN
                     ELNMSWEDEENLIVRISQIETRLLSIDGVLDIANTMINSIASNLTIDSNSIVVRGEVV
                     G"
     gene            655..>1143
                     /locus_tag="KOU88_004194"
     CDS             655..>1143
                     /locus_tag="KOU88_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011861041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HBK3213967.1"
                     /translation="MDKEINLINYLPQILQDKEEYIKVFNAENKEIKTLHDKLKDLSN
                     DQFLEDLTISGIKRWEKIMSITPKSNESLEDRRFRIFSKYISKLPYSERFLRNWLDNV
                     VGEGNYELTINNATYNIHLESDARNQDWFEEVHSFVSNIKPCNMTLDYTRVLISKDNY
                     MNF"
BASE COUNT          465 a          117 c          228 g          333 t
ORIGIN      
        1 ttggtcagtt gattccaatt gaatatgtag acaaattaga aactgctgag ttaactgaaa
       61 tactaattaa tggagaagat gaagaatcag aggacagttt aaggcaacga tattatgata
      121 gtctaaattc tcaatctttt ggggggaata tacaaaacta taaggatgaa gttaataaat
      181 tgcctgacgt tgggggagtt aaagtatatc cagtttggaa cggtggaggt actgttaagt
      241 tagtaataat taattcaaat tttaaagtac caagtactga tttagttaat ttagttcaag
      301 aagaaattga cccaaatatg aaaggagaag gtttaggatt agcaccaata ggtcatagag
      361 ttacagttga aggagttaca agtacaacta taaatatatc agcagaaata acatataaga
      421 gtggatatac atgggagaat ataaaatcaa ttgcagaaga agcaatagac gactatttaa
      481 atgagttaaa tatgagttgg gaagatgaag aaaacttaat agtccgtata tctcagatag
      541 aaactcgttt gttaagtata gatggagtat tagatattgc aaatacgatg ataaatagta
      601 ttgcatctaa tctaacaata gatagtaaca gcatagtagt gagaggtgag gtagttggat
      661 aaagagatta atctaataaa ttacttacca cagattttac aggataaaga agaatatata
      721 aaagtattta atgcagaaaa caaagaaata aaaacactac atgataaatt aaaggaccta
      781 tcaaatgacc agtttttaga ggacctaact ataagtggta taaaaagatg ggaaaagata
      841 atgtctataa ctcctaaaag taatgagagt ttagaagata gaaggtttag gatttttagt
      901 aaatatataa gtaaactacc ttactcagag agatttttaa ggaactggct agataatgta
      961 gttggagaag gcaattatga attaactatt aataatgcta cttataacat acaccttgag
     1021 agtgatgcta gaaatcaaga ttggtttgag gaagttcatt cttttgtaag taatattaag
     1081 ccatgtaaca tgacactgga ttacactaga gtgcttataa gcaaagacaa ttatatgaat
     1141 ttt
//
LOCUS       DAFAZV010000166         1132 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFAZV010000166 DAFAZV010000000
VERSION     DAFAZV010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1132
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.183"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..192)
                     /locus_tag="KOU88_004195"
     CDS             complement(<1..192)
                     /locus_tag="KOU88_004195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213968.1"
                     /translation="MIKIKDKYEIKDSISFDYSNKRPLEERVSEMYKKAGKYLIDISD
                     KLATDTIDGSSLKPIIIKFE"
     gene            complement(245..715)
                     /locus_tag="KOU88_004196"
     CDS             complement(245..715)
                     /locus_tag="KOU88_004196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HBK3213969.1"
                     /translation="MAQQIKARDTISASKAECFVTIKGKRYNFMQAINLEAKMEKNKS
                     EIPILGSTTKGNKSTGSKYSGNATFYYNTSIFRELLYEYKETGEDIYFDIQITNEDPT
                     SSVGRQTIILEDCNMDSGIIAKFDADGEYLDEDMDFTFENWKLVEKFNIANGME"
     gene            complement(737..>1132)
                     /locus_tag="KOU88_004197"
     CDS             complement(737..>1132)
                     /locus_tag="KOU88_004197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3213970.1"
                     /translation="LKSGKFIFHKVGDEVHVLEDINTFVSFTDDKNDDFSSNQSVRVL
                     DQIANDIATLFNTKYLGEVPNDKSGRISFWNDVVKHHEQLQNMRAIEDFKADDVSVEP
                     GSDKKTVVVSDAVKVISAMSKLYMTVSVS"
BASE COUNT          350 a          222 c          114 g          446 t
ORIGIN      
        1 ttcaaatttt atgattattg gctttaatga cgaaccatca attgtatctg ttgctaactt
       61 atctgaaata tctataagat attttcctgc ctttttatac atctcgctga cacgttcttc
      121 caaaggtctt ttattgctat aatcaaaaga aattgaatct tttatctcat atttatcctt
      181 aattttaatc atctcctatt cttataaata aaaaatacac atacataaat cataaatgtg
      241 tattttactc cataccattt gctatattaa atttctcaac taatttccaa ttctcaaaag
      301 taaaatccat atcttcatct aaatactccc catcagcatc aaatttagca attatgcctg
      361 agtccatatt gcaatcttcc agtattatag tttgacgacc cactgaactt gttgggtctt
      421 cattggtaat ttgtatatcg aagtaaatat cctcaccagt ttctttatac tcatacaaca
      481 attctctaaa tatagaggta ttataataaa atgttgcatt tcctgaatat ttacttcctg
      541 ttgatttatt tccttttgta gtactaccta atataggtat ctcactctta ttcttttcca
      601 ttttagcttc taagttaata gcttgcataa aattatatct tttacctttt atagttacaa
      661 aacactctgc cttagatgca cttattgtat ctcttgcttt tatttgttgt gccattatta
      721 ttctcctttc ttattgttaa ctaactgaaa cagtcatata aagcttactc atagcactaa
      781 taacttttac agcatcactt actacaacag tcttcttgtc gcttccaggt tctacagaaa
      841 catcatcagc tttgaaatct tctattgctc tcatattttg cagttgttca tgatgcttaa
      901 ctacatcatt ccaaaacgag atacgaccag atttatcatt tggtacttca cccaagtact
      961 ttgtattaaa taaagtcgct atatcattag caatttggtc aagtactcta acactttggt
     1021 tacttgaaaa atcgtcattt ttatcatctg taaatgatac aaaagtattt atgtcctcta
     1081 acacatgaac ttcatcacca actttatgaa atataaattt accactcttt ag
//
LOCUS       DAFAZV010000167         1115 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFAZV010000167 DAFAZV010000000
VERSION     DAFAZV010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1115)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1115)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1115
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.184"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..834
                     /locus_tag="KOU88_004198"
     CDS             <1..834
                     /locus_tag="KOU88_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009243519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK3213971.1"
                     /translation="EKYARENGISEYVNVLLAIIQAESGGTAEDVMQSSESLGLPPNS
                     LDTESSIKQGCKYFASLLSYCKNQGIDDLNVAIQSYNYGGGYVGYVTGNGKKHTFNLA
                     ENFAREKSGGKKVTYTNPIAVAKNGGWRYGYGNMFYVELVNQYLTVPQVSGELAQKVM
                     NEALKYQGWKYVYGGSSPTTSFDCSGLTQWCYGKAGISLPRTAQAQYDATQHLPLSQA
                     KAGDLVFFHSTYNAGSYVTHVGIYVGNNQMYHAGDPIGYADLSSSYWQQHLIGAGRVK
                     Q"
     gene            851..>1115
                     /locus_tag="KOU88_004199"
     CDS             851..>1115
                     /locus_tag="KOU88_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011860758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK3213972.1"
                     /translation="MFKKNKKQTETIKEPKEKKVHTVKVGTHKKTVIALWVVLIASVS
                     FGVYKNFTAIDQHTTHEKEIIELRLQDTNGIENFVKNFAKSYYT"
BASE COUNT          355 a          214 c          274 g          272 t
ORIGIN      
        1 gaaaaatatg ccagagaaaa cggtatttcc gagtatgtca atgtgctatt ggctatcatt
       61 caagcagaaa gtggcggtac ggcagaagat gttatgcaga gttcagaaag tctgggacta
      121 ccgcctaatt ccttagatac ggaaagctca atcaagcagg ggtgtaaata ttttgcgtcc
      181 ctgctttctt actgcaaaaa tcaaggtatc gacgatttga atgtagcgat acagtcctat
      241 aactatggcg gtggctatgt gggatatgtg actggaaacg ggaaaaagca tacctttaat
      301 cttgcggaaa attttgcccg tgagaaatcg ggtggaaaga aagtaaccta caccaacccg
      361 atagccgttg cgaagaacgg gggctggcgg tatggctatg gaaatatgtt ctacgtcgaa
      421 ttagtcaatc agtatttaac tgttccgcag gtatcgggag agctggcaca aaaggtaatg
      481 aatgaagcat tgaagtatca aggctggaaa tatgtgtatg gcggttcttc tcctacaact
      541 tcctttgact gttcggggct gacgcaatgg tgttatggaa aagctggtat ctccttaccg
      601 agaacagcac aagcccagta tgacgcaacc caacatcttc cactctcgca ggcaaaggct
      661 ggggacttgg tatttttcca ttctacctat aacgctggtt cgtatgtaac ccacgtcggc
      721 atttatgtag ggaataatca gatgtaccat gcaggcgacc cgataggata tgcagattta
      781 agtagcagtt actggcaaca gcacttaatc ggtgcaggac gagtaaaaca atagaaagga
      841 cttgaaaaat atgtttaaga agaataagaa acagacagaa actatcaaag aacctaaaga
      901 aaaaaaggtg catactgtca aggtaggcac acataagaaa accgtgattg cgttgtgggt
      961 ggtgcttatc gcaagcgtga gctttggggt atataagaac tttaccgcta tcgaccaaca
     1021 cacgacccat gaaaaagaaa tcattgagct tcgcttgcag gacaccaacg ggatagaaaa
     1081 tttcgtgaag aactttgcga agtcctatta cacat
//
LOCUS       DAFAZV010000168         1062 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFAZV010000168 DAFAZV010000000
VERSION     DAFAZV010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.186"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            143..877
                     /locus_tag="KOU88_004200"
     CDS             143..877
                     /locus_tag="KOU88_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBK3213973.1"
                     /translation="MYYVYKYINQDTEECLYVGKTENICDRHASHLSNKKENWCNKNL
                     RLEYMELDNKYTMDFYEIYLINKLEPKFNITGKGEMDIAKTSFSYNGQWVIYLERDLM
                     SSLASKRYGINYEVNAKMLGIMRKLKKISSNEEIFIGNENIRIKYYFETVLEGINLEP
                     CILSVAYKTLKESTVGTVISVKREYLSENVCLIIDSIFLNEIMKDPLMSKSDIKDLNS
                     QVNDILKIIGVDCEWNKLSDYCSANS"
BASE COUNT          435 a           96 c          193 g          338 t
ORIGIN      
        1 acatttgaat ataaaattac tgagattttc caacaaatag aggatatttt tcacatacta
       61 gaagttggat atacatggca agaattattt gaaatatata agggctgtaa atatgacaat
      121 taagaattgg agaaaataaa aaatgtatta tgtttataaa tatattaatc aagatacgga
      181 agaatgttta tacgttggga aaacagagaa tatctgtgat agacacgcta gtcatttaag
      241 taataaaaaa gaaaattggt gtaataagaa tttaagactt gagtatatgg aattagataa
      301 taaatatact atggattttt atgagattta cttaataaat aaactagagc ctaaatttaa
      361 tattactgga aaaggagaaa tggatatcgc taaaacatca ttttcctata atggtcagtg
      421 ggtaatttat ttagaaagag acttaatgtc gagtttggca tcaaagagat atggaataaa
      481 ttatgaagtg aatgctaaga tgttaggcat aatgagaaaa ttaaagaaga taagcagcaa
      541 tgaagaaata tttattggaa atgaaaatat aagaataaaa tattactttg aaacagtact
      601 agaaggaatt aatttagaac catgcatatt gagtgtagca tataagacac taaaagaaag
      661 tacagttgga acagtaatct cagtaaaacg tgaatattta tcagaaaatg tatgtttaat
      721 cattgatagt atttttctaa atgaaataat gaaagatcct ttaatgtcta aatcagatat
      781 taaagattta aatagccaag tcaatgatat tcttaaaata ataggggttg attgtgagtg
      841 gaacaagctt tctgattatt gtagtgcaaa ctcttaactg atattacaaa atatggtata
      901 attaaattta gcaagaagag cgtaatatac aatctataga gtggagttca tgtacaaaag
      961 attatcctcc caacgattcg aggggaggtg agttacatgg ataacttttt gtttaatgtt
     1021 ttagctagtt taacagctag tgtggtagtt tacttaatca gt
//
LOCUS       DAFAZV010000169         1031 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFAZV010000169 DAFAZV010000000
VERSION     DAFAZV010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 1031)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1031)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1031
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.187"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..>1031
                     /locus_tag="KOU88_004201"
     CDS             <1..>1031
                     /locus_tag="KOU88_004201"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213974.1"
                     /translation="DVDIGKIRGMASEGMLTADIVKNSLLSAAEQTNAEFEKMPYTFG
                     QIWTSIKNNVVMIFGVIQKKIEQSMSSRGFRTFIDNFINGLYVLGNVFFNIFNGIINI
                     LSSPFFQAFTNTIIVCVSLIAQALGWVITQALNIVNVFAQNWSIISPIILGIASVFII
                     FQAVLLATKIATLGNVIANIAHAAASSFSALMTNIQAAALMRANGATLSATIATWGLN
                     AALLANPITWVVLGFLAFIVIIFVAVAAINKFAGTSLTVLGTIVGAAFAAAAFIQNIM
                     IWLLNKCVDVNEGIANGWNQCVFLMKQAIAKGVIFIIEKMASLNNSVNSAGNALGKAF
                     IDGANIAIRG"
BASE COUNT          350 a          138 c          210 g          333 t
ORIGIN      
        1 gacgtagaca taggaaaaat aagaggaatg gcatcagagg gaatgttaac ggcagatatt
       61 gtaaaaaact cattactttc agcagcagag cagaccaatg cagagttcga gaagatgcct
      121 tatacatttg gacagatttg gacatcaata aaaaataacg tagtcatgat ttttggtgtt
      181 atacagaaaa aaatagaaca atctatgtct agccgaggtt tccgaacctt tatagataat
      241 tttataaatg gattatatgt tttaggtaat gtgtttttta acatttttaa tggaattata
      301 aatatattaa gtagtccttt ttttcaagct ttcacaaaca ctattattgt atgtgttagt
      361 ttgatagcac aagcattagg ttgggtgata acacaagcgt tgaatattgt taatgtattt
      421 gcacagaatt ggagtattat ttctcctata attttgggga tagcttctgt ttttataata
      481 tttcaagcag ttttactagc aactaaaata gctaccttag gcaatgtgat tgcaaatatt
      541 gctcatgctg cagcttcttc attttctgca ctaatgacta atattcaagc agcagcatta
      601 atgcgtgcaa atggagcgac tttatcagca acaatagcta cttggggatt gaatgctgca
      661 cttttagcta atccaattac atgggtagta ttaggatttt tagcattcat agtcattata
      721 tttgtagcag tagcagcaat aaataaattt gcaggaacgt ctttgactgt cctaggtaca
      781 attgtgggtg cggcatttgc agcggcagca tttatacaaa atataatgat atggttatta
      841 aataaatgtg tagatgtaaa tgaaggaatt gcgaatggat ggaatcagtg tgtttttctt
      901 atgaaacaag caatagcgaa gggagtaata tttataatag aaaaaatggc atctctaaat
      961 aattctgtaa attcagcagg gaatgcactc gggaaagcat tcatagatgg ggcgaacata
     1021 gcaataagag g
//
LOCUS       DAFAZV010000170          920 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFAZV010000170 DAFAZV010000000
VERSION     DAFAZV010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..920
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.196"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(4..264)
                     /locus_tag="KOU88_004202"
     CDS             complement(4..264)
                     /locus_tag="KOU88_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213975.1"
                     /translation="MKEEKLELTEKELHCIARHLQNEIMEMVFRGNREAPTSCEVCDY
                     LQECEGDFTCMYHSFTKLSKITGVKVTAFKYCFPDENPKATI"
     gene            427..639
                     /locus_tag="KOU88_004203"
     CDS             427..639
                     /locus_tag="KOU88_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213976.1"
                     /translation="MNMCKIKTLREKCSLIDDKVEFSGEYKTFPGFAGSKLLECECNK
                     NYICKIQIMTANSNCPLFKKARQLQY"
     gene            complement(658..876)
                     /locus_tag="KOU88_004204"
     CDS             complement(658..876)
                     /locus_tag="KOU88_004204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003425624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213977.1"
                     /translation="MADKTVELTEKDLHCIARHLQNEVLEIAFRGNREAPTSCEVCDY
                     FEECKDYFTHIDTFIKLSEMTGVDIFTK"
BASE COUNT          294 a          159 c          122 g          345 t
ORIGIN      
        1 ttcttagata gtagctttgg gattttcatc tggaaaacaa tacttaaatg cagtcacttt
       61 tacacctgtt attttgctta atttagtaaa agaatgatac atacaagtaa aatcgccctc
      121 acattcttgc aggtaatcgc aaacttcaca tgatgtgggg gcttctctat tccctctaaa
      181 caccatctcc ataatttcat tttgcaaatg tcttgctatg caatgtaatt ctttttcagt
      241 aagttctaac ttttcctctt tcatgagcaa cctcctaatt tatttaacat ttaattcttt
      301 atctgtttca ttgagtttgt aactaaattt aattgacctg tgttttaatt ctacgccatg
      361 ataatttgca tgttataatt aatttgagca tattggcagt atgttcaaat taattatagg
      421 gtggtgatga atatgtgcaa aattaaaacc ttaagagaaa aatgctctct tattgacgat
      481 aaagttgaat tttctggtga atataaaact tttcctggat tcgctggatc aaaactttta
      541 gagtgcgaat gtaataaaaa ttacatttgc aaaattcaaa taatgactgc taatagcaac
      601 tgtcctcttt ttaaaaaagc acgtcaatta caatactaaa attttaattt actaaattta
      661 tttagtaaaa atatctacac ctgtcatttc acttaatttt ataaaagtgt ctatatgggt
      721 gaaatagtcc ttgcattctt cgaagtaatc gcaaacttca caagatgtag gggcttctct
      781 gtttcctcta aatgctatct ctaacacttc attttgcaaa tgccttgcaa tgcagtgcaa
      841 atccttttca gtaagttcta cagttttatc tgccataaac aatcctccta atttatactt
      901 aactaaatat ctgacttaat
//
LOCUS       DAFAZV010000171          839 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFAZV010000171 DAFAZV010000000
VERSION     DAFAZV010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 839)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 839)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..839
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.199"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..537
                     /locus_tag="KOU88_004205"
     CDS             <1..537
                     /locus_tag="KOU88_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK3213978.1"
                     /translation="LFGMCTGLRIGDILALKVADVTDVKLDKKGKKIRVSKDWIRVIE
                     EKRDYDREVFLSDVIKSAIENYTQDKPGEEFLFKSGKRKKFNRPIQTRQAGRIIKGAA
                     EKVGIKENVATHSLRKTFARHIYDEEENKTYALELIRKILGHKTIEITRRYIGIDKDE
                     EVKAITKFTNKLKKRKRN"
BASE COUNT          365 a           67 c          175 g          232 t
ORIGIN      
        1 ttatttggaa tgtgtactgg gcttagaata ggggatatat tagcacttaa agttgcagat
       61 gtaacagatg taaagttaga taaaaaaggg aagaagataa gagtatctaa ggattggatt
      121 agagttatag aagaaaaaag agactatgat agagaagttt tcttatctga tgtaataaag
      181 agtgctatag aaaactatac tcaagataaa cctggagagg agttcttatt taaaagtggt
      241 aagagaaaga agtttaatag gcctatccaa acaaggcaag caggaagaat aataaaagga
      301 gcagcagaaa aggtaggaat aaaagaaaat gttgcaacac actctttaag aaagacattt
      361 gcaaggcata tttatgatga agaagagaat aagacttatg ctttagaact tataagaaag
      421 attctaggac ataagacaat agaaataact agaaggtata taggaataga taaggatgaa
      481 gaagtaaaag caataactaa atttactaat aagttaaaga aaagaaaaag aaattaaaat
      541 atcttgtatt ttatctaaaa tttaaatgtt acgtttttca gcaacaggac attattagaa
      601 tgtaaagagc ctcaataata gaatttccaa agaataggat agatttatta aaatgtctga
      661 aaatatatat taaaggtcat ttattcaagg gatttatagg gatgtagata tttaaatgtt
      721 tatttagaag ctgagtaaag aggtgattaa ttggatgtga atgaagttga aataatcgat
      781 agtagctatg aaaaaggtaa agagttgaca gaagatcagt gcaatatggt aactctatt
//
LOCUS       DAFAZV010000172          828 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFAZV010000172 DAFAZV010000000
VERSION     DAFAZV010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..828
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.201"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..493
                     /locus_tag="KOU88_004206"
     CDS             <1..493
                     /locus_tag="KOU88_004206"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213979.1"
                     /translation="LGSPFLGTDKLDTTKTKTQTLKNTLASNITNKGIVTNSTESLQD
                     MISKVSSIKDLRQASGTASAFKGRFYDDYYYLWSVNLPQLNFVPLVVFVYADYRRLSI
                     WVKSPFSKYIFYGKKDNVKTELKDFYIKELDDGISTETVIHLYGASGDTYEVQWLAIG
                     QEA"
     gene            496..789
                     /locus_tag="KOU88_004207"
     CDS             496..789
                     /locus_tag="KOU88_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015984860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213980.1"
                     /translation="MEVGKLIIYDNKGKILFQGGEGKGDLIPYDKDMKVDWVEIKYNS
                     IDYSKYRIIGINVETKEPVLEEIKVELTEEEKRIQELENQILIAENEKVGGIL"
BASE COUNT          353 a           77 c          157 g          241 t
ORIGIN      
        1 attgggaagt ccatttttag gaacagataa attagataca actaaaacaa aaacacaaac
       61 attaaaaaat acacttgcaa gtaatataac taataaaggt attgtaacaa acagtacaga
      121 aagtttgcaa gatatgataa gtaaagttag cagtataaaa gatttaagac aagcaagtgg
      181 tacagctagt gcatttaaag gcagatttta tgatgattat tactacctat ggagtgtaaa
      241 tttaccacaa ttaaattttg tgccacttgt tgtttttgtc tatgctgact atagacggct
      301 ttcgatttgg gttaaaagtc ctttttctaa atatattttt tatggtaaaa aagataatgt
      361 aaaaacagag ttaaaagatt tttatataaa agagttagac gatggaattt ctacagagac
      421 agttatacat ctctatgggg cttcaggaga cacttatgaa gtacaatggt tagcaatagg
      481 tcaggaggct taaatatgga agtaggaaaa ttaataattt atgataataa agggaaaatt
      541 ttatttcaag gtggagaagg aaaaggagat ttaattccat atgacaaaga catgaaagtt
      601 gattgggtag agataaaata caattctata gattattcta aatacaggat tattggaata
      661 aatgtagaaa caaaagaacc tgttttagaa gaaataaaag tagaattaac agaagaagaa
      721 aagagaatac aagaattaga aaatcaaata ttgattgcag aaaacgaaaa agtaggagga
      781 attttataat gaatataaat aatgttgtcg taagaatatt ggcagaga
//
LOCUS       DAFAZV010000173          751 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFAZV010000173 DAFAZV010000000
VERSION     DAFAZV010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 751)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 751)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..751
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.203"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            102..>751
                     /locus_tag="KOU88_004208"
     CDS             102..>751
                     /locus_tag="KOU88_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4428 domain-containing protein"
                     /protein_id="HBK3213981.1"
                     /translation="MGLFGKKKADICCICDTEIGVLNIEDGWICNSCFKEYCDALSMT
                     KAPKILKKLDIEKTISSTKKNNELQKIFNPTNNIENYIEFDEDNKKWLVSKRSENDKK
                     APIIHSYENIVKFEILEDGESIVSGGVGRAIVGGALFGATGAIVGGVTGKKTARKVVN
                     SFKIKITINDIDNPVEYIELINKKTKTNSSVYEKAYKDAHKILSTLSAITQSIKVA"
BASE COUNT          315 a           72 c          137 g          227 t
ORIGIN      
        1 ctaaagaagc tagaaggagt agaagaagat aatatctaat gtaaaaattt tactaatata
       61 gtataataat cttataaaat tattgtactg gaggaaaact tatggggtta tttgggaaga
      121 aaaaagcaga tatatgctgt atttgtgata ctgagatagg agtgttgaat attgaagatg
      181 gttggatatg caattcttgt tttaaagaat attgtgatgc actttctatg actaaagcac
      241 ctaaaatttt aaaaaaatta gatattgaaa aaactatatc atcaactaaa aaaaacaatg
      301 aactccaaaa aatatttaat ccaactaata atatagagaa ctatatagaa tttgatgaag
      361 ataataaaaa atggcttgtg tctaaaagaa gtgaaaacga taaaaaagct cctatcattc
      421 attcttatga aaatattgtg aaatttgaaa ttttagaaga tggagagtct atagttagtg
      481 gaggagtggg aagagctata gttggaggag ctttgtttgg tgctactgga gctatagttg
      541 gaggagtaac aggcaaaaaa acagcaagaa aggttgttaa ttcatttaaa attaaaataa
      601 caattaacga tattgataat cctgttgagt atattgaatt gattaataaa aagactaaaa
      661 ccaattccag tgtttatgag aaagcataca aagatgcaca taaaatttta tcaacattat
      721 ccgctattac acaaagtatt aaagttgcag a
//
LOCUS       DAFAZV010000174          746 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFAZV010000174 DAFAZV010000000
VERSION     DAFAZV010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..746
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.205"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..>746)
                     /locus_tag="KOU88_004209"
     CDS             complement(<1..>746)
                     /locus_tag="KOU88_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBK3213982.1"
                     /translation="QGVESGKTKFTELQNKILNDVKPALKVLEDSGVNFKDKFKESIT
                     SIKDKFNELKNILAGNIKTNIDNLVKAFEPLKPHLDNLKECFDKVKKAITDFFTPAKQ
                     VGDTVNKVSQPMDSVKKSTDGIKLSFQSLTQALAPVKAWFQGFMPFLSQIGQQLLPSI
                     GIAIAGVVGGIILAFTWVLNTLTAIITTVSGIINGIMSFISGIINVIMGLITGNADQT
                     MDGLKQIFDSGVGVIKSIWNGLVDLVSGVL"
BASE COUNT          238 a          135 c           93 g          280 t
ORIGIN      
        1 tccagtacac cactaactag atcaacaagg ccattccaaa ttgattttat tacacctact
       61 ccactatcaa atatttgttt aagtccatcc atagtttgat cagcatttcc tgttataagc
      121 cccataataa cattaataat tccagatata aaagacataa ttccatttat gattccagat
      181 actgttgtta ttattgcggt taatgtattt aaaacccatg taaatgctaa aattattccg
      241 ccaacaacac cagctattgc aattcctata gatggtaaaa gttgttgtcc tatttgtgat
      301 aggaaaggca taaatccttg aaaccaagct ttaacaggag caagtgcttg agttaaactt
      361 tggaaagaaa gtttaattcc atcagtagac tttttaacac tatccattgg ttggcttact
      421 ttgtttactg tatctccaac ctgtttggct ggagtaaaaa aatcagtaat cgctttttta
      481 accttatcaa aacactcttt caaattatct aaatgaggtt ttaaaggttc aaatgctttt
      541 actaaattat ctatatttgt tttaatattt ccagctaata tgttctttaa ttcattaaat
      601 ttatccttta ttgaagttat tgactcctta aacttatcct taaaatttac tccagaatcc
      661 tctaggacct ttaatgcagg tttaacatca tttaatattt tgttttgcag ttctgtaaat
      721 ttagtttttc cagattcaac tccttg
//
LOCUS       DAFAZV010000175          743 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFAZV010000175 DAFAZV010000000
VERSION     DAFAZV010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..743
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.206"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            312..614
                     /locus_tag="KOU88_004210"
     CDS             312..614
                     /locus_tag="KOU88_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213983.1"
                     /translation="MEVNLHTGKDEFFKNHEVAKNYIGGLYKLIDVYKFSMESVSVLT
                     RIDLDKLNNFYAGEASLNYDELCLIESVIITPLVGAFETAEHNYNMIIKARKERKL"
BASE COUNT          315 a           66 c          117 g          245 t
ORIGIN      
        1 ttaaaatgat acaattttat atcatttctt attattaaga aatagaaaaa cactttaatt
       61 gattaaagaa taattttata taatcttgta aaaatataaa aagaacactt aatatattag
      121 cttgaaaaat attaagtgtt ctttttttct attctattta aataaaatag aatagaaaaa
      181 atgattgaaa atattattct atcgtgatag aatgaaaaaa acagaatatt ctaccgtgat
      241 agaatattct gttttgaaga agaagtaaat attatttgaa ggttaaaaat ataagaacaa
      301 tggagggaat tatggaagta aacctacata caggaaaaga tgaatttttt aagaaccatg
      361 aagtagcaaa aaactatata ggtggattat ataaacttat tgatgtttac aaattctcaa
      421 tggaatcagt ttccgtttta actagaatag atttagataa gttaaataat ttctatgctg
      481 gagaagctag tttaaactat gatgaattgt gcttaataga aagtgtaatt ataactcctt
      541 tggtaggagc atttgaaact gctgagcata attacaatat gattattaag gcacgtaaag
      601 aaaggaaact gtaattgaga ataatataaa aaaatagggg gaaaacaaat gaaaaaaaca
      661 attgctttat tactaacgct ttgcgcagta atgattccat ttacagcttt tgctgatgga
      721 aatgattatg aaggtactgg aaa
//
LOCUS       DAFAZV010000176          720 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFAZV010000176 DAFAZV010000000
VERSION     DAFAZV010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.208"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..>720)
                     /locus_tag="KOU88_004211"
     CDS             complement(<1..>720)
                     /locus_tag="KOU88_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018112737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK3213984.1"
                     /translation="KTLGKNASICSKAWLHVWEDDNNDFQYANIDPRQIRAVYSSDLN
                     RKLLAVLREYEKINDEGKEYVIYEYWTDECCYTYQNKDGNNNINDLEILNKFIEKNLD
                     NKLETQTNVYKHNFGEVPFIEFLNNDLEVRDLDNVKHLIDVYDKVYSGFVNDIEDIQE
                     VIFVLTNYGGADLTEFLKGLKEYKTIDLQSSGADDKSGLSTITINIPIEARDSLLKTT
                     EKQIYVQGQGVDPKPENFANTS"
BASE COUNT          211 a          131 c           89 g          289 t
ORIGIN      
        1 acttgtattg gcaaaatttt cgggtttagg gtcaactcct tgaccttgta catatatttg
       61 cttttcagtt gttttaagaa gtgaatctcg agcttcaatt ggaatattta ttgtaattgt
      121 acttaaccca ctcttatcat ctgcaccact actttgtaaa tcaatagttt tatattcttt
      181 aagtcctttt aaaaactctg ttaagtctgc acctccatag ttcgtaagaa cgaaaataac
      241 ttcttgtata tcttcaatat cattcacaaa accgctataa accttgtcgt atacatcaat
      301 gaggtgttta acattatcta aatctcttac ctctaaatca ttgtttagaa attcgataaa
      361 tggaacttct ccaaaattgt gtttatatac attagtttga gtttcaagtt tattatctaa
      421 gtttttctct ataaatttat taagtatctc taagtcgtta atattattat ttccatcttt
      481 attttgataa gtataacaac attcatctgt ccaatactca tagatgacat attcttttcc
      541 ttcatcatta atcttttcat actctctaag tactgcaaga agctttctgt ttaaatctga
      601 tgaatatact gctcttattt ggcgagggtc tatattagca tattggaagt cattgttatc
      661 atcctcccaa acatgtagcc atgctttaga gcatatacta gcatttttcc ccagcgtttt
//
LOCUS       DAFAZV010000177          682 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFAZV010000177 DAFAZV010000000
VERSION     DAFAZV010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..682
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.211"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..204
                     /locus_tag="KOU88_004212"
     CDS             <1..204
                     /locus_tag="KOU88_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003431627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213985.1"
                     /translation="KATIVEAKATTTKVIIGKDLETGRVEASEFKNQLAGQLSIDVSD
                     SNETDEIEENSSGVIDFRNASSK"
     gene            255..>682
                     /locus_tag="KOU88_004213"
     CDS             255..>682
                     /locus_tag="KOU88_004213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213986.1"
                     /translation="MIRNAMEYLVKLGKRETVCVDGFKYTTDALEIIKEPKANELEIT
                     TLSGLVDYIKSGIDHEEDELLLIQVLTPRKVLLKSALRKNRDRETYIECVALLPDKRF
                     DRPLDLDTFNIMLQSAFIKNNDRDTLLKIAGNIQESTVKNV"
BASE COUNT          311 a           63 c          122 g          186 t
ORIGIN      
        1 aaagcaacta tagtagaagc aaaagcgaca acaactaaag ttataatagg aaaagattta
       61 gagacaggaa gagttgaagc atctgaattt aaaaatcaac tagctggtca gttgtctata
      121 gatgtttcag atagtaatga aactgatgaa atagaagaaa atagttctgg tgtaattgat
      181 tttagaaatg caagttcaaa gtagattaag aaagtaaata aaatataaat ttaaataaaa
      241 aggagaataa aaaaatgata agaaatgcaa tggaatattt agttaagtta ggaaaaagag
      301 aaacagtatg tgtagatggg tttaagtaca caacagatgc attagaaata ataaaagaac
      361 caaaagctaa tgaattagaa ataactacat tgagtggttt agtagattat ataaaaagtg
      421 gcatagatca tgaagaagat gagttgttat taatacaagt cttaactcca agaaaagtgc
      481 ttttaaaatc tgctttgaga aaaaatagag atagagaaac ttatattgaa tgtgtagcac
      541 tacttccaga taaaagattt gacagacctt tagatttaga cacttttaat ataatgctac
      601 aatcagcatt tataaaaaat aatgatagag atacactttt aaaaattgca ggaaatatcc
      661 aagaatctac agtaaaaaat gt
//
LOCUS       DAFAZV010000178          675 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFAZV010000178 DAFAZV010000000
VERSION     DAFAZV010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.212"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            184..591
                     /locus_tag="KOU88_004214"
     CDS             184..591
                     /locus_tag="KOU88_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBK3213987.1"
                     /translation="MKVFLVIDGEPVGKERPRFNLATKRTYTPNKTRDYEELIRWLYQ
                     SKVKYYFTGYIKMTLRCYYSIAKSNSKKVKEQKRNNVLRPSKKPDIDNVVKIIADSLN
                     EIAYKDDTQIVEVVASKYYSDNPRVEVILEDVI"
BASE COUNT          276 a           66 c          134 g          199 t
ORIGIN      
        1 tctagaagaa gaattaataa aaaaaaactc tcacttagag ctagaagatt tacgctaaat
       61 aggaagtgat tttatgaaac gaagaagatg cagttggtgt ggcaagttat tttattttaa
      121 ggaaaaatct aaggagattt attgttgtaa ggaatgtaga aagaaggcta agaaggtgaa
      181 aaaatgaaag tttttcttgt aatagatggg gaaccagttg gcaaagaaag acctagattt
      241 aatttggcta ctaaaaggac ctatacacct aataagacta gagattatga ggaactaata
      301 agatggttat atcaatctaa agttaagtat tattttacag gttatataaa aatgacttta
      361 agatgttatt attctatagc taaaagtaac agtaaaaagg ttaaagagca gaaaagaaat
      421 aatgtgttaa gacctagtaa gaaacccgat attgacaatg tggtaaagat tatagctgat
      481 tcactcaatg agatagctta taaggatgat acacagattg ttgaggttgt agctagtaaa
      541 tattatagtg ataatcccag ggttgaggtt atattagaag atgttatcta accaacggaa
      601 aaatccgttc gttaaattat gtccttagtt tttcataaaa atgtgaaaaa gctaaataaa
      661 gaatatatca aacga
//
LOCUS       DAFAZV010000179          664 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFAZV010000179 DAFAZV010000000
VERSION     DAFAZV010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.213"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            complement(<1..>664)
                     /locus_tag="KOU88_004215"
     rRNA            complement(<1..>664)
                     /locus_tag="KOU88_004215"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          152 a          191 c          151 g          170 t
ORIGIN      
        1 gatccagccg caccttccga tacggctacc ttgttacgac ttcaccccag ttattgattc
       61 caccttcgac gacttcttcc aaaaggttag ataatcggct tcgggcgtct ccaactcccg
      121 tggtgtgacg ggcggtgtgt acaagacccg ggaacgcatt caccgcagca ttctgatctg
      181 cgattactag taactccagc ttcatgtagg cgagtttcag cctacaatcc gaactgagag
      241 tagctttaag ggattagctc caccttacgg cttggcaacc ctctgtacta cccattgtag
      301 cacgtgtgta gccctaagca taaggggcat gatgatttga cgtcatcccc accttcctcc
      361 aggttatccc tggcagtctc tctagagtgc ccaacttaat gatggcaact aaagacaagg
      421 gttgcgctcg ttgcgggact taacccaaca tctcacgaca cgagctgacg acaaccatgc
      481 accacctgtc accaatgtcc ccgaagggaa ctctccgatt aaggagatgt cattgggatg
      541 tcaagcttag gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc cgctacttgt
      601 gcgggtcccc gtcaattcct ttgagtttca ctcttgcgag cgtacttccc aggcggagta
      661 ctta
//
LOCUS       DAFAZV010000180          659 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFAZV010000180 DAFAZV010000000
VERSION     DAFAZV010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..659
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.215"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..>659
                     /locus_tag="KOU88_004216"
     rRNA            <1..>659
                     /locus_tag="KOU88_004216"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          187 a          136 c          195 g          141 t
ORIGIN      
        1 tttaactgag cgttcagtta cttgacgtag acccgaaacc gggcgaccta cccatgagca
       61 ggatgaagcg aaagtaaaat ttcgtggagg tccgaaccca cgagcgttga aaagctcggg
      121 gatgacttgt gggtagcggt gaaattccaa tcgagcccgg agatagctgg ttctccccga
      181 aatagcttta gggctagcct caaggtgaga gatacggagg tagagcactg aatgtcctag
      241 ggggtattgc acctaccgaa gactatcaaa ctccgaatgc cgtcatctta tacttgggag
      301 tcagactgtg ggtgataaga ttcatagtcg aaagggcaac agcccagatc gtcagctaag
      361 gtccctaaat gtaagttaag tggtaaagga tgtgggattg cacagacaac caggatgttg
      421 gcttagaagc agccactcat tcaaagagtg cgtaatagct cactggtcga gtgatcctgc
      481 gccgaagatt tccggggcta aaacttacta ccgaagctac ggcatcagta atgatgggta
      541 ggggagcttc ccatacgggt tgaagcatga ccgtaaggac atgtggacag tatgggagtg
      601 agaatgttgg catgagtagc gagatgtggg tgagaatccc acaggccgta aacccaagg
//
LOCUS       DAFAZV010000181          658 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFAZV010000181 DAFAZV010000000
VERSION     DAFAZV010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.216"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..>658
                     /locus_tag="KOU88_004217"
     CDS             <1..>658
                     /locus_tag="KOU88_004217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213988.1"
                     /translation="GGGGWFGGAGMNGVGAGGGGSGYVLTKDSYKPTGYTPTSEYYFD
                     NVVMESGGNTAGAYGYAKITLLQALPFLTVSSYNSITATFKADHTDPTLLTKIEYFID
                     DILKETITTDLTTEKTINYTLEDNALHILKIVVTDSNNTTAEKVLSISKNIMPLPENV
                     NLNDISTKLVEVNAGFKVGKTSIINTLALKNIEASLNNTLVELSEKIKTSFDSSDASV
                     Q"
BASE COUNT          258 a           89 c          121 g          190 t
ORIGIN      
        1 cggtggaggt ggctggtttg gtggtgcagg aatgaatggt gtgggagcag gtggaggtgg
       61 aagtggctac gtattaacta aagatagtta taagcctact ggctacacac caacatctga
      121 atattatttt gataatgttg ttatggaatc tggtggaaat actgctggtg cttatggtta
      181 tgctaaaata acattactac aagcattacc atttttaaca gtatcttctt ataattccat
      241 tacagctaca tttaaagctg accacacaga ccctacacta ttaactaaaa tagaatactt
      301 tatagatgat atactaaaag aaactataac aacagattta acaacagaga aaacaattaa
      361 ctacacatta gaagataatg cactacacat acttaaaata gttgttacag acagtaataa
      421 tactacagca gaaaaagtat taagtataag taagaatata atgccactac ccgaaaatgt
      481 aaatttaaat gatatatcaa caaaattagt tgaggttaat gcaggattta aagttgggaa
      541 aacaagtatt ataaatactt tagcattaaa gaatatagaa gcaagtttaa ataatacact
      601 tgttgagttg tcagagaaaa taaaaacaag ttttgatagt tcagacgcta gtgtgcag
//
LOCUS       DAFAZV010000182          641 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFAZV010000182 DAFAZV010000000
VERSION     DAFAZV010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..641
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.218"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..546
                     /locus_tag="KOU88_004218"
     CDS             <1..546
                     /locus_tag="KOU88_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK3213989.1"
                     /translation="FMIREIGYLDDENNLIAISKYKECYKPSIEQGAVVDMKVKTVLI
                     VSNVNNIELKIDPTIIFATLKDIQDLETKIGTTKTELTSNIETAKTELNNKIGDTTQL
                     TTTDKTNIVSAINEVKTSVDGIETTADKTSYNNATSNLTATNVQGAIDEIVVKQNELN
                     TEVNGQRIKGISIANSLIDMI"
BASE COUNT          291 a           72 c          115 g          163 t
ORIGIN      
        1 tttatgataa gagaaatagg atatttagat gatgaaaata atttaattgc catttctaaa
       61 tacaaagagt gttataaacc ttctatagaa caaggtgcag tggtagacat gaaggttaaa
      121 actgtgctta ttgtatctaa tgtaaataat atagaactta aaattgaccc aacaataatc
      181 tttgcaacac tcaaagatat acaagactta gaaactaaaa taggtacaac taaaacagaa
      241 ttaacaagca acatagaaac tgctaaaaca gagttaaaca ataaaatagg agatacaaca
      301 caacttacta caacagataa aacaaatata gttagtgcaa tcaatgaggt gaaaactagt
      361 gtagatggta tagaaacaac agcagataaa acaagttata ataatgctac tagtaatctt
      421 actgctacga atgtgcaagg ggcaatagat gagattgtag taaaacaaaa tgaattaaat
      481 acagaagtga atggacagag aataaaagga atttcaatag caaatagttt gatagacatg
      541 atataagaga ggtgagaata tgacagaaaa gttgactgat aatgctagtt tgagagaact
      601 tatgatagca tttgaaagta caaaaaatga tttgcagata g
//
LOCUS       DAFAZV010000183          634 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFAZV010000183 DAFAZV010000000
VERSION     DAFAZV010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..634
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.219"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..>634
                     /locus_tag="KOU88_004219"
     rRNA            <1..>634
                     /locus_tag="KOU88_004219"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          178 a          138 c          183 g          135 t
ORIGIN      
        1 tgatggggag cgaaatttag tagcgaagta gctgatttca cactgtcaag aaaagtctct
       61 atcgaggtta aaggtacccg taccgcaaac cgacacaggt gggtgaggag agtatcctaa
      121 ggccagcgag agaactgttg ttaaggaact cggcaaaatg accccgtaac ttagggataa
      181 ggggtgccac catcaggtgg ccgcagagaa taggcccaag cgactgttta ccaaaaacat
      241 aggtttctgc taagtcgcaa gacgatgtat aggagctgac gcctgcccgg tgctggaagg
      301 ttaaggggat ctgttagagc aatcgaagca gtgaacttaa gccccagtaa acggcggccg
      361 taactataac ggtcctaagg tagcgaaatt ccttgtcggg taagttccga cccgcacgaa
      421 aggcgtaacg atttgggcac tgtctcaaca acagactcgg tgaaattgta attccggtga
      481 agatgccgga tacctgcgac aggacggaaa gaccccatgg agctttactg tagcttgaca
      541 ttgggtcttg gtactacatg tacaggatag gtgggaggct ttgaaaccag gacgccagtt
      601 ttggcggagc catccttggg ataccaccct tgta
//
LOCUS       DAFAZV010000184          620 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFAZV010000184 DAFAZV010000000
VERSION     DAFAZV010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..620
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.220"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            34..>620
                     /locus_tag="KOU88_004220"
     CDS             34..>620
                     /locus_tag="KOU88_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009900160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3213990.1"
                     /translation="MHEKMAYITLARYADNESICFPSNATIAKKMGCSINTARKAIKN
                     LEEKQLIKKIPRKKNEKENDSNLYCVMSLRGMSRDDIPIAPDDKGVCQEMIYPIAPDD
                     KGVCQEMIYPIAPDDKGVCQEMIGKKTYNKKTYIKSNTTTQKESKTDYLDLSFLDLDI
                     EKVKLTKDEYDKLISRFGKKYIHDKIVSLENYIVNG"
BASE COUNT          276 a           65 c          118 g          161 t
ORIGIN      
        1 gaaaatgaag tcatagataa ttcaagttta agtatgcatg aaaaaatggc atatataaca
       61 ttggcaaggt atgcagacaa tgaaagtatt tgttttccca gtaatgcaac tatagctaaa
      121 aaaatgggat gtagtataaa tacagccagg aaagcaataa aaaatttaga ggaaaagcaa
      181 ttaattaaaa agattcctag aaagaaaaat gaaaaggaaa atgatagtaa tttatattgt
      241 gttatgagct taaggggtat gtcaagagat gatataccta tagcaccaga tgataaaggg
      301 gtatgtcaag agatgatata ccctatagca ccagatgata aaggggtatg tcaagagatg
      361 atatacccta tagcaccaga tgataaaggg gtatgtcaag agatgatagg taaaaagact
      421 tataataaaa agacttatat aaaaagtaat actactacac aaaaagaatc taaaactgat
      481 tatttagacc tatcattctt ggacttagat atagaaaaag taaaactaac taaagatgaa
      541 tatgacaaac ttataagcag gtttgggaag aaatacatac atgataaaat tgttagttta
      601 gaaaactata tcgtaaatgg
//
LOCUS       DAFAZV010000185          586 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.222, whole genome shotgun sequence.
ACCESSION   DAFAZV010000185 DAFAZV010000000
VERSION     DAFAZV010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.222"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
BASE COUNT          215 a           81 c           47 g          243 t
ORIGIN      
        1 tcttttatag atgctccatt tcttataaaa gtctttgcta gataactaaa tattaattgt
       61 atatttcttt ctagattatc cactcgtatt tacttcctct tacttcttct atttttttag
      121 gctcagtgag taatgcaatt aataaaataa acaatgtaaa tttttctcta ataaaatcac
      181 cctctttgaa atacatctct ggtttttaaa ttttgctaga aaatttctag aactcatttt
      241 ccataaaaaa taattttttc aaaatagaag gacaccccct attaataaaa aaaataaata
      301 tattaaagta ttttgaatta ttttcttgca agaaatattt ttttgattag aattattaat
      361 tatctttcaa ctattcctta aatatgtatt ttcggcatag ttaaaaagaa cctagcattt
      421 ccaataggtt cacatatcct ataataatcc acatcacttc actgtatgaa actttaatta
      481 ttaagtctca ctaaatttta ttaaattagc tataactaaa gttaaataca atatatgatt
      541 taattattaa agtaaatata tatataatat atgttttgct ttaatt
//
LOCUS       DAFAZV010000186          586 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFAZV010000186 DAFAZV010000000
VERSION     DAFAZV010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.223"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
BASE COUNT          212 a           80 c           48 g          246 t
ORIGIN      
        1 tcttttatag atgctccatt tcttataaag gtctttgcca gataactaaa tattaattgt
       61 atatttcttt ctaaattatc cactcgtatt tacttcctct tgcttcttct atttttttag
      121 gttcagtgag taatgcaatt aataaaataa acaatgcaaa tttttttcta ataaaatcac
      181 cctctttgaa atatatctct ggtttttaaa ttttgctaga aaatttctag aactcatttt
      241 ctataaaaaa tgcttttttt aaaatagaag gacacccctc tatcaataaa aaaataaata
      301 tattaaaatg ttttgaatta ttttcttgca aaaaatattt ttttgattag aattattaat
      361 tatctttcaa ctattcctta aatatgtatt ttcggcatag ttaaaaagaa cctagcattt
      421 ccaataggtt cacatatcct ataataatcc acatcacttc actgtatgaa actttaatta
      481 ttaagtctca ctaaatttta ttaaattagc tataactaaa gttaaataca atatatgatt
      541 taattattaa agtaaatata tatataatat atgttttgct ttaatt
//
LOCUS       DAFAZV010000187          542 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFAZV010000187 DAFAZV010000000
VERSION     DAFAZV010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..542
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.228"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..246
                     /locus_tag="KOU88_004221"
     CDS             <1..246
                     /locus_tag="KOU88_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213991.1"
                     /translation="TGLKDCIRKEIYEGDIVSYILSFEEFIGEVKFEEGFFVIDNEVL
                     GECVGLFHEIAVVKVIGNIYENPEMLEKIRKPKVLEV"
     gene            249..521
                     /locus_tag="KOU88_004222"
     CDS             249..521
                     /locus_tag="KOU88_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009894696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3213992.1"
                     /translation="MKHECKKLFLECDKGSFEINDTRIGEVMFESTEIDNPFERVKYE
                     GKATFEIVSGWEYLQREMLWLKILHLSAVVAKIMQYKMLGILIREM"
BASE COUNT          207 a           38 c          130 g          167 t
ORIGIN      
        1 acaggtttga aggattgtat tagaaaagaa atctatgagg gtgatattgt ttcatacatc
       61 ttatcatttg aagaatttat aggagaggta aaatttgaag aaggtttctt tgtaatagat
      121 aatgaagtgc taggagaatg cgttgggtta tttcatgaaa ttgcagtggt taaagttatt
      181 ggcaatatat atgaaaatcc tgagatgtta gaaaagataa ggaaacctaa agtgttggag
      241 gtctaaaagt gaaacatgag tgtaagaaac ttttcttgga atgtgataag ggaagttttg
      301 agataaatga tacaagaatt ggagaagtaa tgttcgagag tacagaaata gacaatccgt
      361 ttgagagagt aaaatatgaa ggtaaagcta cttttgaaat agtatctgga tgggagtatc
      421 tacaaagaga aatgttgtgg cttaagatat tgcatttatc agcagttgta gcaaaaataa
      481 tgcaatataa aatgttaggt attttaataa gggagatgta ataaaatggc taaaatttgg
      541 at
//
LOCUS       DAFAZV010000188          531 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFAZV010000188 DAFAZV010000000
VERSION     DAFAZV010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.230"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..>531
                     /locus_tag="KOU88_004223"
     rRNA            <1..>531
                     /locus_tag="KOU88_004223"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          144 a          112 c          175 g          100 t
ORIGIN      
        1 accaaggcga cgatcagtag ccgacctgag agggtgatcg gccacattgg aactgagaca
       61 cggtccaaac tcctacggga ggcagcagtg gggaatattg cacaatgggc gaaagcctga
      121 tgcagcaacg ccgcgtgagt gatgaaggcc ttcgggtcgt aaaactctgt cctcaaggaa
      181 gataatgacg gtacttgagg aggaagcccc ggctaactac gtgccagcag ccgcggtaat
      241 acgtaggggg ctagcgttat ccggatttac tgggcgtaaa gggtgcgtag gcggtctttc
      301 aagtcaggag tgaaaggcta cggctcaacc gtagtaagct cttgaaactg ggagacttga
      361 gtgcaggaga ggagagtgga attcctagtg tagcggtgaa atgcgtagat attaggagga
      421 acaccagttg cgaaggcggc tctctggact gtaactgacg ctgaggcacg aaagcgtggg
      481 gagcaaacag gattagatac cctggtagtc cacgctgtaa acgatgagta c
//
LOCUS       DAFAZV010000189          491 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.241, whole genome shotgun sequence.
ACCESSION   DAFAZV010000189 DAFAZV010000000
VERSION     DAFAZV010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..491
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.241"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            154..270
                     /gene="rrf"
                     /locus_tag="KOU88_004224"
     rRNA            154..270
                     /gene="rrf"
                     /locus_tag="KOU88_004224"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            276..364
                     /locus_tag="KOU88_004225"
     tRNA            276..364
                     /locus_tag="KOU88_004225"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:310..312,aa:Leu,seq:taa)
     gene            376..452
                     /locus_tag="KOU88_004226"
     tRNA            376..452
                     /locus_tag="KOU88_004226"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:410..412,aa:Ile,seq:cat)
BASE COUNT          160 a           90 c          108 g          133 t
ORIGIN      
        1 taactctata tttttaaact tgtcaaaact tatggatttt taatagtttt ataaggcaaa
       61 aaatcgaata aaaaaagtat tgacacaata agacaaagat gttattataa tacttgtctt
      121 agaaaaaaag ttaaatgaaa atttagacaa taatctggtt ataatagcag agaggataca
      181 cctgttccca ttccgaacac agaagttaag ctctctagcg ctgatggtac ttggtgggaa
      241 actgcctggg agagtaggac atagccaggt gatgtgccga agtggcggaa ctggcagacg
      301 cacaggactt aaaatcctgc gggacttacc tctcgtaccg gttcgattcc ggtcttcggc
      361 accacaaatt attgtgggcc attagctcag ttggttagag cgcccggctc ataaccggta
      421 ggtctggggt tcgagtccct gatggcccac cacaataatt taaagaactt tgaaaattaa
      481 acagtaggtt a
//
LOCUS       DAFAZV010000190          481 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.denovo.248, whole genome shotgun sequence.
ACCESSION   DAFAZV010000190 DAFAZV010000000
VERSION     DAFAZV010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.denovo.248"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            <1..>481
                     /locus_tag="KOU88_004227"
     rRNA            <1..>481
                     /locus_tag="KOU88_004227"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          115 a          111 c          151 g          104 t
ORIGIN      
        1 actgtcaggt gggcagtttg actggggcgg tcgcctccca aaaggtaacg gaggcgctca
       61 aaggttctct cagtacggtc ggaaatcgta cgtagagtgt aaaggcaaaa gagagcttga
      121 ttgcaagaca tacaggtcga gcaaggatga aaatcggact tagtgatccg gtggttctgc
      181 gtggaagggc catcgctcaa cggataaaag ctaccctggg gataacaggc ttatctcccc
      241 caagagtcca catcgacggg gaggtttggc acctcgatgt cggctcatca catcctgggg
      301 ctgtagtagg tcccaagggt tgggctgttc gcccattaaa gtggtacgcg agctgggttc
      361 agaacgtcgt gagacagttc ggtccctatc cgtcgcaggc gtaggaaatt tgagaagacc
      421 tgtccttagt acgagaggac cgggatggac gtacctctgg tgtaccagtt gtcctgccaa
      481 g
//
LOCUS       DAFAZV010000191        15199 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.guided.073, whole genome shotgun sequence.
ACCESSION   DAFAZV010000191 DAFAZV010000000
VERSION     DAFAZV010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 15199)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15199)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15199
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.guided.073"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            278..1231
                     /gene="blaCDD"
                     /locus_tag="KOU88_004228"
     CDS             278..1231
                     /gene="blaCDD"
                     /locus_tag="KOU88_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDD family class D beta-lactamase"
                     /protein_id="HBK3213993.1"
                     /translation="MKRKKNFIWIAILLVGVVMVMYYVGKKHNDINQKTDKNYIKSEL
                     NKSELNKSKIENNDKNKKEKINMVDYSDCFEGISGGAIFYNTKNKEYNIYNKELIETR
                     RSPCSTFKIVSTLIGLEKGVINSKESVMGYDGTEYPNKNWNKNLSLEEAFKESCVWYY
                     KKLIDKVDAKSVQNILDDLKYGNCDISEWEGDLKNGKGHLNGFWLESSLQISPKEQVQ
                     TMAKIFEGDTNFKKEHINILRDIMKIDINDKNINVYGKTGTGFDEKNKRVDAWFVGML
                     EREGDTYYFAIKSDDSNKEITGPKVKEIAINIIKKYYSVRE"
     gene            1575..2258
                     /locus_tag="KOU88_004229"
     CDS             1575..2258
                     /locus_tag="KOU88_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK3213994.1"
                     /translation="MEILKCENLTKIYGSNQTRVTALNNVNLSVQKGDFVSIVGASGS
                     GKSTLLHLLGGVDRPTSGKIYVEDTEISSLKEEALAVFRRRKVGLIYQFYNLIPTLDV
                     RKNILLPMLLDKRKVDEDRFSEIVSILGLSDRLNHLPSQLSGGQQQRVSIARSLIYRP
                     AILLADEPTGNLDRKNSEEIVDLLNLSNKRFNQTILLITHDEKIALEANRIVTMEDGV
                     IVSEKVVKK"
     gene            2255..4915
                     /locus_tag="KOU88_004230"
     CDS             2255..4915
                     /locus_tag="KOU88_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK3213995.1"
                     /translation="MNILQEYTLDFVRRNKRSSIAIMLAILLTTTMMSSLCGLLYTMW
                     TDFIRLSIEKEGNWHGELFDYTYGSDLPLIENFSSVDDVMVKGQWYVGKINDEKRDYI
                     IYRNATSEYWNSMPEKDTIIEGRRPNNANEIALSKQYFENNPSVKIGDKITLPIGYRI
                     LNGKPLEPIAPKSKGESFKKISEATLTIVGKVDVSTSSVIPAYTALGYLDKTSIKPND
                     SITVYLRFKNIRDTYKELPKLAKSLGWKTNEYGKYNLKYNSNYLLKMLVFSPEQKASM
                     SSISKFSTPIMYLTIAIFTVAVFVMVIYNAFSLSANARLTQLGILSSVGASPKQIKRS
                     VVFEGFLLTIIPLPIGLFLGWLLCNRLIVYVNSVNYHTDVPEVVFTYGIPAFLPAVLL
                     TIVTVWISALIPARKVSKISPIEAIRQGDSVKIKKSHKYSLGKIFGIEGELASNALRA
                     RKKSYRTATISLTLSFLLLTCFLHIIANQEGAKAVYGSDNYKDQRDIAVYLENSEPVE
                     SAFIEKLDNTEGVKSSLYYQKMSASTWLTEKDASKELAKNGGFKSIVSSKKYSPIERD
                     GKFRIISNIIGLDDKSFTEYCRQVSVDPKLFYNTKNPTSIVYNKEEDINRSTRRNKVY
                     IDYLNLSIGDNIKLNEKVYDEDKGDYTYNMKVGAITSTLPKIVDTSSKYTLMQIVPMS
                     MVQEISKNYDEVSRLRSNRLIGVFKVNNREDIPRVREKLESIYNKDYGSGDYSIEDVL
                     ESEKQKASGIKTMNLIVGFITGLLAMIGLSNVLATVSGNIRSRRQEFAMLRSVGLSPE
                     GIKKMLILEGLFLGITPLLLSIPVQIGIVYAFLRINEIYFIEYLPFAPISTIIGFTIL
                     ILFIVIASYMTGYKQLKNENIVESIKNETI"
     gene            complement(5096..6277)
                     /locus_tag="KOU88_004231"
     CDS             complement(5096..6277)
                     /locus_tag="KOU88_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016728749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3213996.1"
                     /translation="MKTPRNINSTVVFIIFCLIVTFLLSVILTTITSFNEYNVLSKAL
                     GASYEYNPKSTESILKSLKNSSDKDFKTGNEILSKHGYSKSTFWSKNFFYFLVISFGI
                     ISTMATVIYIIKHRTNKQKLSRINNLTQYLEEVNLGKESVLLRCEDEFSHLEDEIYKT
                     VGELRCSKEFALKERQTLSDNLADIAHQLKTPITSMSLMAQLLSENCPDEEIDYINRL
                     TNQISRLERLVSSLLTLSKLDASTLIFESKLIDVHSLLTYAIEPIEGSLREKHQTFTI
                     EASPSVEFEIDINWTLEALLNILKNCSEHIEDGGYIVAYYSQNPLYVEIIIEDNGKGF
                     AQEELPYIFNRFYRGKNASKDSIGIGLALSKSIIERQNGTLHAENCHNGGARFIIKFY
                     T"
     gene            complement(6277..6939)
                     /locus_tag="KOU88_004232"
     CDS             complement(6277..6939)
                     /locus_tag="KOU88_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009901935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK3213997.1"
                     /translation="MAKILLLEDDDTITFGIKTSLEKKNHTVCCYNTIAEAKKNFDKT
                     IDLILLDLNLPDGIGYEFCQYVKSIEDTPVIFLTVRDDEKDIIRGLDMGADDYVVKPF
                     LLSVLQSRINAVLRRTHSNTNNTITCENISLNKVEVKAYLDNVEVPLTAGEYKLLLSL
                     MENKNRAMTRTKLLEMLWDVDGNFVNDNTLTVTIKRLREKLKNPPCIKTLRGIGYRME
                     DS"
     gene            complement(7071..7709)
                     /locus_tag="KOU88_004233"
     CDS             complement(7071..7709)
                     /locus_tag="KOU88_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003417472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK3213998.1"
                     /translation="MSELSKRDKEKIQRENEIIDKAEKLFCLNGFDNTTMNELAKEVE
                     YTKRTIYKYFSCKEDLFFAVVLRGYKRLWDNVKIESAKGKTGFEKIKLSYFAFHKFYS
                     VEPSLLCLMGMIGIVNSEKSDTDMLFKEKFFSFNKFMFDEIQGMFEIGKNDRSIRHDI
                     EIPTLMYSSIFTLTGFFNLLSVTGKSYLNNFNIDEEKFIETTLALLIDSIKA"
     gene            7888..8493
                     /locus_tag="KOU88_004234"
     CDS             7888..8493
                     /locus_tag="KOU88_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK3213999.1"
                     /translation="MKIKENVLMLDSTRGSNCFIVFDKEIILIDTGLPFMGKNIIKEL
                     KTLGIKLTDIKHILLTHHDVDHISNIKLLKEKTGAKVWAHVEDIPFIIGEKDRPGFKK
                     FIGKAISRRLIKDVEPYGENMQIGNIKIIHTPGHTPGHVCMIFEAVLFAGDLVKNKNG
                     NIVPYPNPWNWDYKKMVKSIRELDNLKYEWICMSHGTPCIK"
     gene            8997..9746
                     /locus_tag="KOU88_004235"
     CDS             8997..9746
                     /locus_tag="KOU88_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3214000.1"
                     /translation="MRLESLVNQNYDNLNENDKIIIKQILICQREYRNFSCEKIANEC
                     NVSRATLLRLCRKIGLDSFSDLKYLLKNNQLEFVNNDNNFHDVCENYRLLMNELQKIS
                     FQDICKIIYDAETIYIYGTGNEQKSLAQEIKRIFLSVGKCVIDLFDIGEIEFMRESFQ
                     KNDLFIIISLSGETKAGIEIAKFINNHIHTISLTRLDNNTIATLCEYNLYVETQKLDT
                     LQAISYEVVGAFYALLDLLHMNYIEYRRRKE"
     gene            9743..10507
                     /locus_tag="KOU88_004236"
     CDS             9743..10507
                     /locus_tag="KOU88_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003434714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK3214001.1"
                     /translation="MKIEGLFNKYYNSFTANDKYICECILNHKEDCIKLSIDEFADKY
                     HISTSALSRFAQKLQLPGYSELRVIIRLNETEVEYKNQSKHQLMDCYNKVIDDIEKKD
                     CSIMFERMKKANRIIVFGEGYSQERVAKEMKRIFLPTGKIIYDVYGYDMIQALNHFIK
                     TDDMIFFISLNGDASTIIDFAKEMRMKGIYMVSITKMISNPLARLCDENLYIQSISIS
                     VDKQLDYDVTTPYFILIELLYIKYKMYLESEHIPRK"
     gene            10606..11427
                     /locus_tag="KOU88_004237"
     CDS             10606..11427
                     /locus_tag="KOU88_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK3214002.1"
                     /translation="MKLYKLLILDIDGTLRDEVYGIPESAKHAIRLCQKNHCSVVICT
                     GRSMGTIQDDVLSLGVDGYIAGGGNYIQYHGELLYNQSFNQRLIKEVVCLLKKREVAF
                     SIESQEKVFMNQKAKEIFETMNQLKGTNSCINKQHIQEKITYENNIEEYKSQDIHKIC
                     LWSNEKVFDEVKDILQDKMELAQRDISSQYYEIIQKDFHKGKAIKRLQERLGVTQKET
                     ICFGDGQNDIVMFQASDVTIAMKNSHQQLKDIATSICEDIFDNGIYKELKRRNII"
     gene            11441..13105
                     /locus_tag="KOU88_004238"
     CDS             11441..13105
                     /locus_tag="KOU88_004238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003426300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBK3214003.1"
                     /translation="MEKKWWQKEIVYQIYPRSFQDSNNDGIGDLQGIISRLDYLKDLG
                     ITSLWLCPIFKSPMDDNGYDISDYLDIASEFGSMEDLKELIKESKDRGIKIILDLVLN
                     HTSDEHPWFQEALKNPESPYHDYYIFKKGNDLPNNWRSVFGGSVWEKVENRDEYYFHS
                     FGKKQPDLNWENPILRSELYQMINTWSQMGVAGFRVDAITFIKKNLSFQSLESDGVDG
                     LVKCTKTVRNQPGIEKMLYELKENTFKKYDCMTVAEAAGISYDQLGDFIGEDGFFSMV
                     FDFKHADLDVASGSEWFKRISWTIPDLRKCILDSQMYVQEHGWAANFIENHDQPRATT
                     KYLLQYERNDDAVKMLGAMYFFLRGTPFIYQGQELGMTNFKRDTINDFNDLSSIDQYY
                     RSIDESYSEEEALEFVNLRSRDNARTPFPWADKENAGFSDTTPWLKVIENYKDINAQS
                     QINNSESILEFYKKMIKLRQDSEYSDCLIYGSIEPIDIESDDIIAYRRQLDLVVIDCY
                     YNFSDKPVEIRVEEKYDIVFQNLDDINLLNKTVRLKPFHAVLLKVR"
     gene            13110..14984
                     /locus_tag="KOU88_004239"
     CDS             13110..14984
                     /locus_tag="KOU88_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009888302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK3214004.1"
                     /translation="MNKYNKIANELIKIIGEDNIISITHCATRLRVMVKDREIINDKK
                     VEKVDEVKGVFFTSGQYQIILGTGIVNKVYAEVEKMGLKTLSKKEQDELVKNNETGFK
                     KVMRTLADIFVPIIPVIAATGLFLGLKGCLFNDNVLGLFGMSSANIPLYIQTLVSVLT
                     ETAFAFLPAIIVWSAFKVFGGTPVIGLVIGLMLVSPILPNAYSVADPSNEIEAIMAFG
                     FIPIVGCQGSVLTAIVTAFIGANLEKWFRKHMPNVLDLIFTPFFVMLITMLVILLGVG
                     PIMHTIELKMVDIISLLIDLPLGIGGFIIGFTYPLAVITGLHHTYVMIETSLLANTGF
                     NALITLCAMYGFANIGTCLAFMKKSKNNQVKQTAVGAMLSQLFGISEPVLFGIQLRYN
                     LKPLIIMCASSGLGAAILSILHIQSNSYGLAVLPSYLMYIYDGYNLITYLLVSIFVVA
                     FCFIVTCLFGVPKEAINEDEDEELVFNENNENFVFPAKGKIVALENVPDETFSKKMLG
                     DGFAIDIIDGKIVSPISGKLETVFSSGHAFGIKGTNGEVLIHVGIDTVALNGDGFDVA
                     VKQGDMVKQGDVLVNVDLKRIHELGKSTLTMVLFPDGKKVNILDINKDVKIGQRICVE
                     "
BASE COUNT         5709 a         1748 c         2524 g         5218 t
ORIGIN      
        1 attgtaatat ttaaatatta caatagtaag ttttaaatgt ggaatcaatt attatatcac
       61 aaattaaaag gaggacagga tgttattaat agttacctaa ttatcttcgc aataggttta
      121 atcaacataa ttgtactagg tgaagaaaat ataagagata cagctattca tttagtcttg
      181 tttcttataa gtagaaccta gattggagta tattacaaat aatgtctact attttaatag
      241 taggttataa atttaaatat gggagatgat ataaattatg aaaagaaaaa agaattttat
      301 ttggatagct atcttattgg ttggtgtagt tatggtaatg tattatgtag ggaaaaaaca
      361 taacgatata aatcaaaaaa ctgataagaa ttatataaaa tctgaattaa ataagtctga
      421 attaaataaa tccaaaattg aaaacaatga taaaaacaaa aaagaaaaaa ttaatatggt
      481 tgactatagt gattgttttg aaggtattag tggaggagct attttttata atactaaaaa
      541 taaagaatat aatatatata acaaagaatt aattgaaaca agaaggtcac catgttctac
      601 ttttaaaata gtttcaactt taattggttt agaaaaaggg gtaataaact caaaagaatc
      661 agttatggga tatgatggta cagagtatcc aaataaaaat tggaataaaa atcttagttt
      721 agaagaggca tttaaggagt cttgtgtttg gtattacaaa aaattgatag ataaagttga
      781 tgctaaatct gtccaaaaca ttttagatga tttaaagtat gggaattgcg atattagcga
      841 atgggaaggc gatttaaaaa atggaaaggg acatttaaat ggattttggt tagaatcttc
      901 attacaaata tctccaaaag aacaagtgca aacaatggca aaaatatttg agggagatac
      961 aaactttaaa aaagagcata ttaatatttt aagagatatt atgaaaatag atataaatga
     1021 taaaaacata aatgtatatg gaaaaactgg aacaggattt gatgaaaaaa ataaacgtgt
     1081 ggatgcatgg tttgttggta tgctagagcg tgaaggtgac acctattatt ttgctattaa
     1141 atcagatgat tccaataaag aaattacagg gccaaaggta aaggaaattg caattaatat
     1201 aattaagaaa tattatagtg taagggaata aacttaattt tatttgtaaa tattatttac
     1261 ctatagtctg taatatttat taaataattt tactaaattg agtctatata gagcaaaact
     1321 cctttagtac ataaaatact tgctattgat tattaaattg aatacctata gatttaaagt
     1381 taataccttt taaagactat gtaatatatt aaaagtataa ataaaatata ttgcatagtt
     1441 tttgttttat attataattt taaataatgt gcaaaaacta aacaatattt ttaatagtaa
     1501 tttatatttg tattcatgtc actataatgt cattttaggt tgctaaaatt taaccataaa
     1561 ggagatgatt gtatatggaa atattaaaat gtgaaaatct cacaaaaata tatggttcaa
     1621 atcaaaccag agtgacagcc cttaataatg taaatttatc agttcaaaaa ggtgattttg
     1681 tatccattgt aggagcatct ggttctggca aatctacatt gttacatctg cttgggggag
     1741 tagatagacc tacatctgga aagatttatg ttgaagatac agaaatatca agtttaaagg
     1801 aagaagctct tgcagttttt agacgtagaa aagtaggtct tatttatcaa ttttataatc
     1861 ttatacctac ccttgatgtt agaaaaaata tattattacc catgttactt gataaaagaa
     1921 aggtggatga ggatagattc tctgagattg tatctatatt gggattatct gatagattaa
     1981 accatcttcc aagtcaactt tcaggtggac aacaacaaag ggtatctata gctagaagtt
     2041 taatctatag accagctatt ttattagcag atgagccaac tggtaatctt gatagaaaaa
     2101 attcagaaga aattgtagac ttgttaaact tatcaaataa acgatttaat cagacaatac
     2161 ttcttattac tcatgatgag aaaatagcac tagaggcaaa tcgtattgta actatggaag
     2221 atggagtgat tgtctctgaa aaggtggtga agaaatgaat attcttcaag aatacacctt
     2281 agactttgta cgacgcaata aacgtagtag tatagctata atgttagcta tattacttac
     2341 tacaaccatg atgtcttctt tgtgtggact gttgtatacc atgtggacag attttataag
     2401 actttcaatt gagaaagaag gtaactggca tggtgaattg tttgactata cttatggaag
     2461 tgacttacca ttaattgaaa atttttcttc agttgatgat gtaatggtaa aaggacaatg
     2521 gtatgtaggc aaaattaatg atgagaaaag agattatata atttatagaa atgctacatc
     2581 agagtattgg aattctatgc cagaaaagga tactataata gagggtcgtc gaccaaataa
     2641 tgctaatgaa attgcattat caaaacaata ttttgagaat aatccaagtg taaaaattgg
     2701 tgataaaatt actctcccaa taggatatag aatcttaaat ggaaagcctc ttgaacccat
     2761 agccccaaaa tcgaaagggg aaagttttaa aaaaatttca gaggctacat tgacaatagt
     2821 aggaaaggta gatgtttcta cttcatcagt aatacctgca tatacagctc ttggatatct
     2881 tgataaaaca agtataaaac ctaatgatag tataactgtg tacttgcgat ttaaaaatat
     2941 aagagacacg tataaggaac ttccaaaact tgctaaatca ttgggatgga agactaatga
     3001 atatggaaaa tacaatctta aatacaatag taattatctt ttaaagatgt tagtcttttc
     3061 accagaacag aaagcatcta tgagtagtat atcaaaattt tcaactccta ttatgtatct
     3121 tacaatagca atttttacag tagccgtgtt tgtaatggtg atttacaacg cgttttcact
     3181 gtctgcaaat gctagactta ctcagttagg gatattatct agtgttggtg catcaccaaa
     3241 acaaattaaa aggtctgtag tgtttgaagg ctttttactg acaattatac cattaccaat
     3301 aggtttattt ttaggatggt tattgtgtaa taggcttata gtttatgtta attcagttaa
     3361 ttatcatact gatgttccag aagtggtatt tacttatggt attcctgctt ttctgccagc
     3421 agttttactt acaatagtaa cagtctggat ttctgcactt ataccagcac gaaaagtatc
     3481 aaagatatct cctatagaag caatacgaca aggagatagt gttaaaatca aaaagtcgca
     3541 taaatattca ttaggaaaga tatttggaat agaaggagaa cttgcatcaa acgcactacg
     3601 tgctcgtaaa aaatcttatc gtactgcaac aatatcttta acattatctt ttttattact
     3661 tacatgtttt ttgcatataa ttgcaaatca agaaggagca aaagctgttt atggaagtga
     3721 taattataag gaccaaagag atatagcagt ttatttggaa aatagtgaac ctgtagagtc
     3781 tgctttcatt gaaaaattag ataatacaga aggtgtaaaa agttcactat attatcaaaa
     3841 aatgtctgct tccacttggc tgactgaaaa agatgcatca aaagaacttg cgaaaaatgg
     3901 aggatttaaa agtatagttt catctaaaaa atactctcct atagaacgtg atggcaagtt
     3961 tcgtataatt tcaaatataa ttgggcttga tgataagagt tttacagaat attgtaggca
     4021 agtttctgta gacccaaagt tattttataa tacaaaaaat ccaacctcaa ttgtatataa
     4081 taaggaggaa gatattaatc gtagtacacg tagaaataaa gtatatatag attatttaaa
     4141 tctttcaata ggagataaca ttaaattaaa tgaaaaagta tatgacgaag ataaagggga
     4201 ttatacttac aacatgaaag tgggagctat tacaagcaca cttcctaaaa tagtagatac
     4261 tagttcaaag tatacattaa tgcaaatagt tccaatgtct atggtacagg aaatatctaa
     4321 aaattatgat gaagtaagta ggttacgttc aaataggctg ataggagtat ttaaagtaaa
     4381 taatcgtgag gacattccta gagtaagaga aaaattagag tccatttata ataaagacta
     4441 tggttcagga gattatagta ttgaggatgt tttagaaagt gaaaaacaaa aggctagtgg
     4501 aataaagacc atgaatttaa tagtaggctt tattacaggt ttattggcta tgattggatt
     4561 atcaaatgta cttgctacag tgtcaggaaa tattagaagt agacgacaag agtttgctat
     4621 gttgcgttct gttggattat ctccagaagg cataaaaaag atgcttattt tggaaggttt
     4681 attcttagga attacaccat tactacttag tattcctgtg caaataggaa tagtgtatgc
     4741 ttttctacgt ataaatgaaa tatattttat agagtattta ccatttgcac ctatatctac
     4801 aataataggt tttactatat tgatactttt tattgtaata gcatcatata tgacaggata
     4861 caagcagttg aagaatgaaa atatagtaga atctataaaa aatgaaacaa tataaacaaa
     4921 atctatttga acttatttaa aggtttcgat ttaagactac ttacaagtat agggatagtt
     4981 aagttgtttg tttaataaaa ccttaaatgt aaatagaagt atattactaa aacaatagat
     5041 aacatagaat atagatatag ctggattata ggtattttac ctataatcca gcattttatg
     5101 tgtaaaattt aattatgaat cttgcaccac cattatggca attttctgca tgtagagtac
     5161 cattttgacg ttctataata gactttgata gagcaagccc tataccaata ctgtccttac
     5221 tagcattttt accacgataa aatctattaa aaatatatgg aagttcttcc tgagcaaacc
     5281 ccttaccatt atcttctatg ataatctcaa catatagagg attttgacta taataagcaa
     5341 ctatatatcc accatcttct atatgctcac tacaattttt aagaatattt aaaagagctt
     5401 ctaaagtcca attaatatcg atttcaaatt ctaccgaagg agaagcctcg atagtaaatg
     5461 tctgatgttt ttctcttaaa gaaccttcta taggctcaat tgcataagta agaagagaat
     5521 gtacatctat aagtttgctt tcaaatatta aagtacttgc atccaatttt gataatgtaa
     5581 gtaaagatga aactagtctc tcaagtcttg agatttgatt tgtaagtctg ttaatataat
     5641 ctatttcttc atctggacaa ttttctgaaa gtaattgtgc cataagtgac atagaagtaa
     5701 ttggagtctt aagttgatga gcaatatctg caagattatc tgaaagagtt tgtctttctt
     5761 ttaaagcaaa ttcttttgaa caacgaagtt ccccaactgt tttatatatc tcatcttcaa
     5821 ggtgagaaaa ttcatcttca catcgtaaaa gtacagactc ttttcctaaa ttcacttctt
     5881 ctaagtattg agtaagattg tttattctac tcagtttttg cttatttgtt ctatgtttga
     5941 ttatatatat aactgtagcc attgttgaaa ttataccaaa cgatatcact agaaaataaa
     6001 aaaagttttt actccaaaat gtacttttag aatatccatg ttttgataaa atttcatttc
     6061 ctgttttaaa atccttatca ctagaatttt tcagtgattt tagtatactt tctgtagact
     6121 taggattgta ctcatatgat gcaccaagag ccttagacag tacattgtat tcattaaaag
     6181 aagttatagt tgttagaatt acactcaata aaaaagttac aattaagcag aatattataa
     6241 aaacaactgt actgttgata tttcttggag ttttcactag ctgtcctcca ttctatatcc
     6301 tatgcctctt aacgttttta tacaaggtgg attttttaat ttttctctaa gacgttttat
     6361 tgtaacagta agagtgttat catttacgaa attaccatct acatcccaga gcatttctag
     6421 taactttgta cgagtcatag ctctattttt attttccata agacttagaa gaagtttata
     6481 ttctcctgct gtcaaaggta cttcaacatt atctaaatat gctttgactt caaccttatt
     6541 caagcttata ttttcacatg taatagtatt gttagtattt gaatgagttc ttctaagaac
     6601 tgcattaatt ctggactgaa gtactgagag caaaaacggt ttaaccacat agtcatctgc
     6661 acccatatct aatccacgta taatgtcttt ttcatcatca cggactgtca aaaatatcac
     6721 tggagtatct tctatacttt taacatattg gcaaaactcg tatccaatac catcaggtag
     6781 atttaaatca agcagaatta aatcaatagt tttatcaaaa ttttttttag cttcagcaat
     6841 cgtattataa caacatacag tgtgattttt cttttcaagg gaagttttta ttccaaatgt
     6901 aattgtatca tcatcttcta aaagaagtat tttagccatt tacttttaat cctttcagta
     6961 atttagttat tccattaact aagttattag ttttatgttt aatatttttt atattagaga
     7021 tagaaaaaat tatcatttaa gtatataaac tttaatttat aaacttaggt ttatgcttta
     7081 attgaatcta ttaaaagagc aagagttgtt tcaataaatt tttcctcatc tatattaaag
     7141 ttgttcaggt atgattttcc tgttacagat agtaaattaa aaaatcctgt aagtgtaaat
     7201 attgatgaat acataagagt aggtatttca atatcatgcc taatacttct atcatttttt
     7261 ccaatttcaa acattccttg tatttcatca aacataaatt tattaaaaga aaaaaacttt
     7321 tctttaaaca gcatatcagt atccgatttt tcagagttta caataccaat cattcccata
     7381 aggcataata gagaaggttc tacagagtaa aatttatgaa aagcaaagta tgaaagtttt
     7441 attttttcaa accctgtttt gccttttgca ctttctattt taacattatc ccaaagtctt
     7501 ttatatcctc ttaagacaac agcaaagaat aaatcttctt tacatgaaaa gtacttgtat
     7561 atggtgcgtt tagtatattc aacttctttt gctaattcat tcatagttgt attatcaaat
     7621 ccattaagac aaaataattt ttctgcctta tcaataatct cattttctct ttgtattttt
     7681 tctttatctc tttttgataa ttctgacata taaattattc ctttctattg ataaaaaagt
     7741 atactgatgg tatacttatg taaatataat acttgtatac ctatagtata ctttaataaa
     7801 aaataaaatt aatatcaagt attataacta tttataactt tattaattaa ttatataggt
     7861 aaaataccaa ataaggggaa tttatttatg aagataaaag aaaatgtatt aatgttagat
     7921 agtactcgtg gctcaaattg ttttattgtg tttgataaag aaattattct tatagacaca
     7981 ggtcttcctt ttatggggaa aaatataatt aaagaattaa aaacacttgg cattaaactt
     8041 acagatatta agcatatttt attaactcat catgatgttg accatatatc taatattaaa
     8101 ttattgaaag aaaaaacagg agcaaaagta tgggctcatg tagaggatat accttttatt
     8161 ataggagaga aggatagacc tgggtttaag aagtttattg gaaaggcaat ttccagaagg
     8221 ctcattaagg atgttgaacc ttatggagag aatatgcaga ttgggaatat aaaaattatc
     8281 catactcctg gtcatactcc agggcatgtc tgcatgattt ttgaagctgt attatttgca
     8341 ggtgatttag tcaaaaataa gaatggaaat atagttcctt atcctaatcc atggaattgg
     8401 gattataaaa agatggtgaa atctataaga gaattggata atttaaaata tgaatggata
     8461 tgtatgtctc atggaactcc ttgtattaaa taataaaaat taacatggat taatagaggc
     8521 atagttgctt gtatgtatga taataattta cagcttcttt ttaatatatc atgtatattt
     8581 gtagctgtaa gcatatttat aacaatactt acaattttgt attttaacat ctataataat
     8641 agttttagct ttgttaacta tgaaatttac ttaaagaagt aaatattcaa gtaatagtaa
     8701 ttattaaata agataaaaag taaatggcag atgaattaaa gtaatttcta ccatggaaaa
     8761 tacttttgag ttagaaaaaa ctatatttta gagtatgaag agatgaagct tccgaagaaa
     8821 gcaatatcta aagtacatgt tcgaaaggat aagtactttt tggtgcctgc ttttagcagg
     8881 ttatttttat tttaataaaa ataaaatcaa atgattattt tatccttatt atttaaaact
     8941 cttccctaga aaaagcaact aatgtatatt aaaataatat ttagggagtg gaaaaaatga
     9001 gattagaatc gttagttaac caaaattatg ataatttaaa tgaaaatgat aaaattatta
     9061 ttaaacaaat attgatttgt caaagagaat accgtaattt ttcgtgtgaa aaaattgcaa
     9121 atgaatgtaa tgtttctaga gctactttat taaggctttg tagaaaaatt ggattagatt
     9181 cattctctga tttaaagtat ttacttaaaa ataatcaact agaatttgtt aataatgata
     9241 ataattttca tgatgtttgc gagaattatc gactattaat gaatgaatta caaaaaatat
     9301 catttcaaga tatttgtaaa ataatatatg atgcagaaac aatttatatt tatgggacag
     9361 gtaatgaaca gaaaagttta gctcaagaaa taaagagaat atttctttca gtaggtaaat
     9421 gtgttattga cttatttgat ataggtgaaa ttgaatttat gagagaatca tttcaaaaaa
     9481 atgatttatt tattatcatt tctttgtctg gagaaacaaa agcaggaatt gaaattgcaa
     9541 aatttatcaa caatcatata catacgattt ctttaactag gcttgataat aatacaattg
     9601 caacactttg tgagtataat ctgtatgttg aaacgcaaaa acttgataca ttacaagcta
     9661 tatcttatga agtcgtagga gcattttatg ctctattaga tttgcttcat atgaattaca
     9721 tagagtatag aaggagaaaa gaatgaaaat tgaaggactt ttcaataaat attataattc
     9781 atttacagca aatgataagt atatctgtga gtgtattctt aatcataaag aagattgtat
     9841 taaactttct atagatgaat ttgcagacaa ataccatata tctacaagtg cactttctcg
     9901 ttttgctcaa aaactacaat tacctggata tagtgaatta agagttatta tacgcttaaa
     9961 tgaaacagaa gtagaatata aaaatcaaag taaacaccaa ttaatggatt gttataataa
    10021 ggtgatagat gatatagaga agaaggattg ttcgattatg tttgaaagaa tgaaaaaggc
    10081 aaatcgtata atcgtctttg gagaaggtta ttctcaggaa agagttgcta aagagatgaa
    10141 aaggattttc ttaccaacag ggaaaattat atatgatgtt tatggttatg atatgattca
    10201 ggcacttaat cattttataa aaacagatga tatgattttc tttatttcat tgaatggaga
    10261 tgcatctaca attattgatt ttgctaaaga aatgagaatg aaaggaattt atatggtttc
    10321 tattacaaaa atgataagta atcctttagc aagattatgt gatgaaaacc tgtatattca
    10381 atctatatct atttctgtag ataaacaact ggactacgat gtaacaacac cttattttat
    10441 tttaattgaa ctgctttata ttaaatacaa gatgtattta gaaagtgaac atattccccg
    10501 aaaatgaaaa tttgtgctaa aaatgaacat attttttaaa agatatcaaa atattgatat
    10561 cttttttttt gaatgctatt atgattttga tagtaagaaa ggaagatgaa attgtacaaa
    10621 ttattaatac ttgatataga tggtacgctt agagatgagg tatatggaat cccagaatct
    10681 gcaaagcatg ctatacgttt atgtcaaaag aatcattgca gtgttgttat ttgtactgga
    10741 agaagtatgg gtacaataca agatgatgtt ttatcattag gagttgatgg atatattgca
    10801 ggaggaggta attacattca atatcatggt gaattacttt ataatcaatc ttttaatcaa
    10861 agattgataa aggaagttgt ttgtttatta aaaaagagag aagttgcttt ttcgattgag
    10921 agtcaggaaa aagttttcat gaatcaaaaa gccaaagaaa tatttgaaac aatgaatcag
    10981 ttaaaaggaa ctaattcttg tataaataaa caacatatcc aagaaaaaat aacatatgaa
    11041 aataacattg aagagtataa gtcacaagat atacataaaa tttgtttatg gtcaaatgaa
    11101 aaggtatttg acgaagtgaa agatatacta caagataaaa tggaattagc acagagagat
    11161 atttctagtc agtattatga aattattcaa aaagattttc ataagggcaa agcaattaag
    11221 agattacaag aaagattagg agtaactcaa aaagaaacca tatgttttgg tgatggtcaa
    11281 aatgacattg tcatgtttca agcatcagac gttacaattg caatgaaaaa tagtcatcaa
    11341 caacttaaag atatagcgac atctatatgt gaggacatat tcgataatgg aatttataaa
    11401 gaattaaaaa gaagaaatat catataaaaa ggagtaattt atggaaaaga aatggtggca
    11461 aaaagaaatc gtttatcaaa tttatccaag aagctttcaa gatagtaata atgatggaat
    11521 tggagattta cagggaatta tttctcgttt agattattta aaagatttag gtattacatc
    11581 attgtggtta tgtccaattt ttaaatcacc tatggacgat aatgggtatg atattagtga
    11641 ttatttggat attgcaagtg aatttggaag tatggaagat ttaaaagagt taattaaaga
    11701 aagtaaagat agaggaatca aaattatatt agatttagtt cttaatcata caagtgatga
    11761 acatccttgg tttcaagaag cattaaaaaa tccagaaagt ccttatcatg attattatat
    11821 ttttaaaaaa ggaaacgatt taccaaataa ctggaggtct gtttttggtg gaagtgtttg
    11881 ggaaaaggta gagaatagag acgaatatta ttttcattct tttggtaaaa aacaacctga
    11941 ccttaattgg gaaaatccaa tattaagaag tgaactttac caaatgatta atacctggtc
    12001 tcaaatggga gtggcaggat ttagagttga tgctattaca tttatcaaaa agaatttaag
    12061 ttttcaaagt ttagaaagtg atggtgttga tggtcttgtt aaatgtacaa aaacagttag
    12121 aaatcagcct ggaatagaaa aaatgcttta tgaattaaaa gaaaatacgt ttaaaaaata
    12181 tgattgtatg actgttgctg aagcagcagg tattagctat gaccaactag gtgattttat
    12241 tggagaagat ggtttctttt caatggtctt tgactttaaa catgctgact tagatgttgc
    12301 ttctggtagt gagtggttta aaagaatttc atggacaatt ccagatttaa gaaaatgcat
    12361 tttagatagt caaatgtatg ttcaggaaca tggatgggca gctaatttta ttgaaaatca
    12421 tgaccaacca agagctacaa caaagtatct tttgcaatac gaaaggaatg atgatgcagt
    12481 aaaaatgttg ggagcaatgt atttcttttt aagaggaacc ccatttattt atcagggaca
    12541 ggaattagga atgacaaatt ttaaaagaga taccataaat gattttaatg atttatctag
    12601 cattgaccaa tactatcgtt caatagatga aagttactca gaagaagaag cgttagaatt
    12661 tgtgaattta agaagccgag ataatgcaag aacgccattt ccatgggcag ataaagaaaa
    12721 tgcaggtttt tcagatacaa caccatggtt aaaggttatt gaaaattata aagatattaa
    12781 tgcacagagt cagattaaca attcagagag tattttagaa ttttataaaa agatgataaa
    12841 gttgagacaa gatagtgagt attctgattg tttgatttat ggttcaatag aacctattga
    12901 tatagaaagt gatgatatta ttgcgtatag aaggcaatta gatttggtag ttattgattg
    12961 ttattataat ttttctgata aacctgtaga aataagagta gaagaaaaat atgatattgt
    13021 attccaaaat ttagatgata taaatctatt aaataaaaca gtgcgtttga aaccatttca
    13081 tgcagtatta ttgaaagtga ggtagaaaaa tgaataaata taataaaata gcaaatgagc
    13141 ttattaaaat tattggtgaa gataatatta tttctattac acattgtgcc acaagattaa
    13201 gagtgatggt taaagataga gaaattatta atgataagaa agttgaaaaa gttgatgagg
    13261 ttaaaggggt tttctttact tctggacagt atcaaattat tttaggaaca ggaatagtta
    13321 ataaagttta tgcagaagtt gaaaaaatgg gattaaaaac tttatcaaaa aaagaacaag
    13381 atgaattagt taaaaataat gaaactggat ttaagaaagt tatgagaact ctagcagata
    13441 tatttgttcc tattattcca gttattgcag caacaggatt attcttggga ttaaagggtt
    13501 gtttgtttaa tgataatgta cttggattat ttggaatgtc ttctgcaaat attccattgt
    13561 atattcagac acttgtttcg gttcttacag aaacagcatt tgctttttta ccagcaatta
    13621 ttgtatggtc agcatttaaa gtatttggag gaacacctgt tattggactt gttattggac
    13681 ttatgttagt ttccccaata cttcctaatg catattctgt tgctgaccca tcaaatgaaa
    13741 ttgaagcaat tatggcattt ggatttattc ctattgtagg ttgtcaagga agtgttttaa
    13801 cagctattgt tacagcattt attggagcta atcttgaaaa atggttccgt aaacatatgc
    13861 ctaatgtatt agaccttatt ttcacaccat tttttgttat gctaataaca atgttagtta
    13921 ttttgttagg tgtaggccct ataatgcata caatagaatt aaaaatggtt gatatcatca
    13981 gcttattgat tgatttgcct ttaggaattg gaggatttat tattggattt acatatccat
    14041 tagctgttat tactggctta catcatactt atgtaatgat tgaaacatca ctattagcaa
    14101 atacaggatt taatgccctt attactcttt gtgcaatgta tggatttgcg aatattggaa
    14161 catgtctagc atttatgaaa aaatctaaaa ataatcaagt taaacaaact gcggttggag
    14221 caatgctatc tcaacttttt ggtataagtg agcctgtttt atttgggatt cagcttcgat
    14281 ataatttaaa gcctttgatt attatgtgtg catcttcagg tttaggagca gcaatattat
    14341 caattttaca tattcaatct aattcatatg gattagcagt tttaccttct tatttaatgt
    14401 atatctatga tggatataat ttaatcacat acttattagt atcaatattt gtggttgcat
    14461 tctgctttat tgtaacatgt ttatttggag tgcctaaaga agctataaat gaagatgaag
    14521 acgaagaatt agtgtttaat gaaaataatg aaaactttgt gtttccagct aaggggaaaa
    14581 ttgttgcatt agaaaatgta ccagatgaaa cattttctaa aaaaatgtta ggtgatggtt
    14641 ttgctattga tattatagat ggaaaaattg tttctcctat ttcaggtaaa ttagaaacag
    14701 tattttcaag tggacatgca tttgggatta aaggaactaa tggagaagta ttaattcatg
    14761 ttggaattga tacagttgca ttaaatggag atggctttga tgttgctgtt aaacaaggag
    14821 atatggttaa acagggagat gttcttgtta atgttgattt aaagagaata cacgaattag
    14881 gaaagtctac tttgacaatg gtattgtttc cagatggtaa gaaggtaaat attttggata
    14941 taaacaagga tgtaaaaata ggtcaaagaa tatgtgttga gtagtaggtg atatgtaatg
    15001 actacaaaag aagattatca agagtaattc aatcttttta aagtatcaga aataattcat
    15061 aaactctaaa acaattaaag aggttgtttc aaaatagaga ttgtattgca cccaaattgt
    15121 tgaaatgatg aaaatatatt taacttcata caaaaaatta aatagtggca acaattgagg
    15181 atgtgaggga gagttgcca
//
LOCUS       DAFAZV010000192        14850 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.guided.074, whole genome shotgun sequence.
ACCESSION   DAFAZV010000192 DAFAZV010000000
VERSION     DAFAZV010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 14850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14850
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.guided.074"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            456..794
                     /locus_tag="KOU88_004240"
     CDS             456..794
                     /locus_tag="KOU88_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3214005.1"
                     /translation="MANIGKIIGDRIKVYRTKLGYSQEFLAEKAGLHPTYIGQIERAE
                     TNTSINIIMKIATALDIPLELLFANIITTEGVDNSVPLECYEMINKLTEKEQIAMLEL
                     IKCIIKYKEI"
     gene            816..1133
                     /locus_tag="KOU88_004241"
     CDS             816..1133
                     /locus_tag="KOU88_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK3214006.1"
                     /translation="MNYIGKRLKEERKKANLTSKEFANMVGVSPWYITQIESGKKNPS
                     LKTFIKFVNILNISADVLIKDITSTGKTYLENDINEELKDLNSRELNLISQIIDIIKK
                     NKI"
     gene            1283..1960
                     /locus_tag="KOU88_004242"
     CDS             1283..1960
                     /locus_tag="KOU88_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3214007.1"
                     /translation="MIVIEGSDKFKIAKEYIDVEYTLFSKVTFRYEKLKFKDNAELEK
                     IKMFKYKNGYIPNKLNLSFGYGFSSYKKQIIRETVDTLRLTEIFSSENIEDIKFIKDG
                     TKKLEISIEKVVKFKRRKKRNYVCCYCPDMYRDIKLDKESINKIYNRKIKIEREVNIF
                     EDEDVIINKKVLKFPKSWTKNMQKYWLSENKYPIHSTVIDDDRYKCCNVQYTKNRVII
                     LYYIYNH"
     gene            complement(2288..3055)
                     /locus_tag="KOU88_004243"
     CDS             complement(2288..3055)
                     /locus_tag="KOU88_004243"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBK3214008.1"
                     /translation="MKRKVQVKNITIGEGRPKICVPIIGKNKKDIIKEAKELKDACLD
                     IIEWRVDFFENVENIKEVKEVLYELRSYIHDIPLLFTFRSVVEGGEKLISRDYYTTLN
                     KEISNTGLVDLIDVELFMGDEVIDEVVNFAHKKEVKVIISNHDFNKTPKKEEIVSRLC
                     RMQELGADLPKIAVMPQNEKDVLVLLEATNEMFKIYADRPIITMSMSGMGVISRLCGE
                     IFGSALTFGAAKSVSAPGQISFKELNSVLNLLHKSIN"
     gene            complement(3727..4542)
                     /locus_tag="KOU88_004244"
                     /pseudo
     CDS             complement(3727..4542)
                     /locus_tag="KOU88_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897377.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            4643..5341
                     /locus_tag="KOU88_004245"
     CDS             4643..5341
                     /locus_tag="KOU88_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK3214009.1"
                     /translation="MYKLSYVVRVSTKNLDELKRRCDEVKDFYDDLSIKLVRPFGDML
                     GLHGEFIPVSKRYINDYIQYVTSDFLAGLGFGATQTLGEHEDIYLGYNLDTGKNVYLK
                     PALASQGVKGSITNALASAFIGSLGGGKLFSNNMLVYYAVLFGGQAVIVDPKAERGKW
                     KETLPEIAHEINIVNLTSNDENKGLLDPYVILSRKKDSESLAIDILTFLTGISSRDSD
                     KFLQKNDNWKIIME"
     gene            5429..6049
                     /locus_tag="KOU88_004246"
     CDS             5429..6049
                     /locus_tag="KOU88_004246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003423956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK3214010.1"
                     /translation="MHLIDFMNEDIKKKLVKKTYKKKETILFAEQENEYVILMIDGIA
                     EAFILNVKGNISTIHLYRSGSFFGEMEQFNDGKKPVEIVAFTDCNVYKLHRDDFLNWL
                     RGDFEATKFLIREISSKLVVNAELIEELSSLSVKERLLRCISLHYYRSELNLLTKKQL
                     ASEVNAPIRSINRAINECVQEHLIAYENKRFSVINQREVLKNLPTT"
     gene            6205..6987
                     /locus_tag="KOU88_004247"
     CDS             6205..6987
                     /locus_tag="KOU88_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 6-adenylyltransferase"
                     /protein_id="HBK3214011.1"
                     /translation="MTKTQQKMIQNVLEFSKRDSRIIGLAISSSYITKSLDEYSDLDF
                     LIVADDKSYEEVIEERLLIVEQFGTLVSAFTGEHVGEPRLIISLYDSPVLHVDFKFTT
                     LDGLLDRVEDSAILYEENNCITEIYSKKEAYFPTPDLQWIEDRFWIWVHYACTKIGRR
                     ELFETIDFLSFLRQSVLAPLIQLLLGKLPRGVRKIELDAPQYIEALEKTVANHEYKSC
                     VNALQATINLYLELREELSQSPIVRKVEAERVALQYFQDLIK"
     gene            7112..8038
                     /locus_tag="KOU88_004248"
     CDS             7112..8038
                     /locus_tag="KOU88_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009903090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3214012.1"
                     /translation="MSDILSRITNKIGDKNIVDKLSALSKSDLNSLLLEVFDRQANTL
                     TATDILKSYQLNRFTIPSGIDPEEIHALESKLLRKAFNMDIKTIMLSPSAPLGSCSVF
                     GSVDQYNVVSALRGTETLADPSNMLAIIIADKLKRKEENNTIPIHMATTARVIRAQNF
                     VGKGLYSHFGLYCMVSSGIDTGSYTCEKMLLEKHLNYYKDILSEIENVRFSIILRKRN
                     GYKDNDGFFDRMVETIKLIFPNIELSIHNDDVDNNYYKGINFKLSVKQGNETVEIVDG
                     GFVDWTYQMLGNKRERCLISGIGLERFLVAVS"
     gene            8052..8501
                     /locus_tag="KOU88_004249"
                     /pseudo
     CDS             8052..8501
                     /locus_tag="KOU88_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729090.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            8861..9268
                     /locus_tag="KOU88_004250"
     CDS             8861..9268
                     /locus_tag="KOU88_004250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK3214013.1"
                     /translation="MVDEKTIEHQFDSFCKTVLRNYARDIYDENKRRNDYLVSLESLS
                     LAELSKLSILDDYDSNYICMVSYDYNIRIEDVLMAQAIGKLTKRKQDIILLSFFFNMT
                     NADIATLMDLAENTIHYHKTNALKELKELMQEH"
     gene            9270..9500
                     /locus_tag="KOU88_004251"
     CDS             9270..9500
                     /locus_tag="KOU88_004251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK3214014.1"
                     /translation="MKPTKEVLPFTIILLAVHGDVNAINVILKHFEHYIIRLSQKTLF
                     DEYGNPYIHVEEETKRMLGTKLITAILRFNLS"
     gene            complement(9552..9761)
                     /locus_tag="KOU88_004252"
     CDS             complement(9552..9761)
                     /locus_tag="KOU88_004252"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK3214015.1"
                     /translation="MVQVTAKQPFQRLFTNHYIVALLIKVMAYSICWLSVSQTYLSTL
                     FSCQRTVGIDLPIKNHNSLWAFIDK"
     gene            9890..10093
                     /locus_tag="KOU88_004253"
     CDS             9890..10093
                     /locus_tag="KOU88_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBK3214016.1"
                     /translation="MNNTDVPIWEKYTLTIEEASKYFRIGEKKLRKRADENLDSGWVI
                     MNSNRIQIKRKQFEKIVDTLDVI"
     gene            10171..10524
                     /locus_tag="KOU88_004254"
     CDS             10171..10524
                     /locus_tag="KOU88_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009897397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase DNA-binding domain-containing protein"
                     /protein_id="HBK3214017.1"
                     /translation="MSTEKRRDNKDRILRTGESQRKDGRYAYKYVYSFGKPQFVYSWK
                     LVPTDKPPKGKRDDISLRDKEKAIQNDLDDSIDTIGKKMTVCQLYAKKNGLRKNIRLN
                     TKKGRHYLMKILNKE"
     gene            10596..11228
                     /locus_tag="KOU88_004255"
     CDS             10596..11228
                     /locus_tag="KOU88_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBK3214018.1"
                     /translation="MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYND
                     PRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLMTSGNHSMKSKSTYTFPIFYEEW
                     KLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
                     VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV"
     gene            complement(11598..12467)
                     /locus_tag="KOU88_004256"
     CDS             complement(11598..12467)
                     /locus_tag="KOU88_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003433836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK3214019.1"
                     /translation="MEYDMPLYRPPSEAYSLIIQVTLGCSHNKCTFCSMYKSKKFKIK
                     PLEVIKNEIDIFRRYYKHVERIFLADGDALIIPMEKLRDIILYIKEVFPECERITMYG
                     SPKSIEKKSDDELKELRKLGVKMIYLGLESGSNEVLEDIKKGFSSEQLIKVGRKVKKS
                     GIKLSATVIAGLGGTKKTHQHAVDTGKMLGAISPDYVGVLSLMVEPNTELYDLLKAGE
                     FTILEDKAVLQEIKEMIKNIDANEKIVFRSNHASNYANLKGVLPDDKQRLIDEIDYYL
                     SNQKLKREEYRRL"
     gene            complement(12564..13421)
                     /locus_tag="KOU88_004257"
     CDS             complement(12564..13421)
                     /locus_tag="KOU88_004257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009890403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK3214020.1"
                     /translation="MSKDVKVKRNKKYDTFSITMELERPLLYDEVENKDDKNNNRKFN
                     IKNKIFKGIGILFVLILLGFFIWINKTYEPQKLAKEALVSNSKVEVTVNENISFTPKG
                     RKVSKGLILYPGAKVEIESYAPLARKIAESGYEVVIVKMPLNLAILGTNKAQKVMDSY
                     NNIEHWVIGGHSLGGVAASNFARDNKLIEGVVFLASYPMGDELKELGKKVISIWGSKD
                     GVVNFKSLVESKQKLPDDTTYVEIEGGNHAQFGDYGKQKGDNDAIISQEKQLNITANS
                     IIKFLKNIS"
     gene            complement(13636..>14850)
                     /locus_tag="KOU88_004258"
     CDS             complement(13636..>14850)
                     /locus_tag="KOU88_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016729087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK3214021.1"
                     /translation="SDVLVVATKEINYIKMCLENKDTITDKEILGFRDYVIAQDTKNI
                     NLKEIYSVLENLYEFLVDYKKVKSRDEKKAERKSKIPHEFKRLSIYKKNFNLNSIRFS
                     YAVKIALATAVAGFIMDYFHLRDGRWIMLTVFSLTQPYAENCIQRSRKRIEGTFIGAV
                     IFIVLFSIIKDSTLRSLIVLLAGYINSYVVDYRKLMVCVTVSALGSAVVMGDPNVLTI
                     SRISYVALGAIIALIVNKFILPYDAKTGYQHVIEMYKGIVKNIIDEVNKSIENVADVY
                     YIKNLLLIPSLIEDRLMLINAIYKDKHQEDFLENQKLLISNMYNLYINVNKNKIKDED
                     VEKILRDTNYISNYNVDKYDEGRSVILESIINTKSLGDKIICLNLLQTLNGVKEMYRI
                     SNITKVSIKEAA"
BASE COUNT         5311 a         2180 c         2079 g         5280 t
ORIGIN      
        1 attctaaatg ccttacttat aattaatttt ttatttcacc tatatataat tagatttaaa
       61 aatgtttacc ttaccaatat aatgattaaa ctcaaaagtc ttattgaaaa attttctatt
      121 cacataaatt gttcaatata taaaatagaa aattttttta attttcaaaa tatattctac
      181 atatctaata tgtaattaca ataaaaaatg ctataattaa catattatta attcgtttta
      241 ttattgtagt atggctatga aattatgaaa atatttctct aattaaaaat atgatttatc
      301 catatttgtt tattgtagat acagactata caaaaataaa tagcacttat ttcagtataa
      361 aaacatatat agtctatatt tagactaaaa aagtataaat agtctatata aaacaactta
      421 aactatgaat ataatctaaa gtggagggat aataattggc aaatatagga aaaataatag
      481 gagatagaat aaaagtctat agaacaaaat tgggatatag tcaagagttt ctagcagaaa
      541 aggcaggttt acatccaaca tatattggtc agattgaaag agctgagaca aatacatcta
      601 tcaatattat aatgaaaatt gctactgctt tagacatacc acttgaattg ttatttgcaa
      661 atattattac aacagaaggc gttgataact ctgtaccttt agaatgttat gaaatgatta
      721 ataaattaac tgaaaaagaa caaattgcaa tgctagagtt aataaagtgc atcattaaat
      781 acaaagaaat ataagtgagg gaaatagtaa caataatgaa ttatataggt aaaagactta
      841 aagaagaacg gaaaaaagca aatttaactt caaaagaatt tgcaaatatg gttggagtat
      901 cgccttggta tataactcaa atcgaaagtg gtaaaaagaa tccaagtctt aaaacattca
      961 taaaatttgt aaatatatta aatatttctg cagatgttct tataaaagat attacttcca
     1021 ctggaaaaac atatttagaa aatgatataa atgaagagtt aaaagactta aattcaagag
     1081 aactaaatct gatatcacag attatagaca tcataaaaaa gaataaaata taattcttta
     1141 tattttatat aaaaaaaaag gttatttgaa ataaataacc tttttttgtc tttttgtgtt
     1201 aacattgtct tatagtgcta atgagtacta ttagaccatg ttctatggcc ttattttaat
     1261 ataaaacgat tggagatagg ctatgattgt gattgaaggt agcgataaat ttaagattgc
     1321 aaaagaatat attgatgtag aatatactct ttttagcaaa gtaactttta ggtatgaaaa
     1381 gttgaaattt aaagataatg ctgaattgga aaaaattaag atgtttaaat ataaaaatgg
     1441 ctacatccct aataaattaa acctttcttt tggatatgga ttctcttctt ataaaaagca
     1501 aataattaga gaaactgtag atactttaag attgacagaa attttttcaa gcgagaacat
     1561 agaagatatt aaatttataa aagatggtac aaaaaaatta gaaattagca tagagaaagt
     1621 tgtgaaattt aaacgtcgaa aaaaaagaaa ttatgtttgt tgctattgcc ctgatatgta
     1681 tagagacata aaactcgaca aagaatctat caataagata tacaacagaa aaataaaaat
     1741 agaaagagaa gttaatattt ttgaagatga ggatgttata ataaacaaga aagtattgaa
     1801 gtttccaaag tcttggacaa agaatatgca aaaatattgg ttaagtgaaa ataagtatcc
     1861 catacattct actgtaattg atgatgatag atataaatgt tgtaatgtac aatatacaaa
     1921 aaatagagtg ataatattat attacatata taaccattaa tatacataat tacaaaaaaa
     1981 taatgacaaa tatacataat acaaatatat cttctacttt agataaaaca gttattatga
     2041 aaacttacta tctataaata atagaaatgc tagtatacca tctataatct aatgtctagt
     2101 aggttttaat ggcatatttt aaatatgcca tagttgattt ataagatttt ctatatcact
     2161 ttcaaaatac acactaaata gttgcttttc agatataatt gcccaattta aattttacta
     2221 tctgaaaagt tttttatatt taatttatat cttcaaaaat accgtctaat atttctatat
     2281 aattaattta attaatactc ttatgtaata gattaagtac tgaatttaac tctttaaatg
     2341 atatttgccc tggtgctgaa acactttttg cagctccaaa agtcaatgca gaaccaaata
     2401 tttcaccaca caatctactt ataacaccca ttcctgacat tgacattgtt attattggtc
     2461 tatctgcata aattttaaac atttcatttg tagcttcaag tagcactaac acatcttttt
     2521 cattttgcgg cataacagct attttgggta aatctgcgcc caattcctgc attctacata
     2581 aacgagatac aatctcttct ttttttggag ttttattaaa atcatgatta gatataatta
     2641 ctttcacttc ttttttatga gcaaaattaa ctacttcatc tatgacctca tctcccataa
     2701 ataactctac atctattaaa tctactaaac ctgtattaga aatttcttta ttcaaagtag
     2761 tataataatc tcttgatatt aatttttctc ccccttctac tacacttcta aatgtgaata
     2821 ataaagggat atcatgtata taacttctta attcatagag aacttcctta acttctttaa
     2881 tattttctac attctcaaaa aaatcaactc gccactctat aatatccaaa catgcatctt
     2941 ttaactcttt agcctctttt ataatatctt ttttattttt cccaataatt ggtacacaaa
     3001 ttttaggtct accttctcca atagtaatat tttttacttg aacttttctt ttcatattct
     3061 cctccataat cagaaattct ataggacttt aaattctatt ttctgcacaa tttaattata
     3121 cattaaaaat actatacatt ataaaaatac taatttaaaa ataattttta ttctaattct
     3181 taaaacaatc ccacatattt tagaaaaggt actctataat atacaaacac ttctttttta
     3241 cctaaattta ttttaacatc ctataatttt cacaatattc tttaaatttt actcatataa
     3301 acaatattat tctggatgct aatagaatta atctataaat catagtataa ttatgcagaa
     3361 ataactcgaa tttcactact tatgaagaga ttgaatatta atgaatctaa atcatttgca
     3421 ttacttaaga gttttgacta aagttgaaca ccatacaaaa gtagctactc aattgtttat
     3481 accccaacca agcttaagta atgttatata gattctcgaa aaagaatttg gtatcttttt
     3541 atttgaaaaa cttatattaa atttgattat cttttcataa gttggtaaat gtcgatatat
     3601 cctgtatcta caaggagtat cggcattttc tttttggaag atactttgca taagttggca
     3661 tttaaccgta taagaatgcc atcaaaagta gtaaataagt agtaaactct agtcatacta
     3721 ctaggattat aaccgttcca tttcagctct cgaagaacta aatgaaccat gtgcataata
     3781 gccaagcgtc atagtaatgt ttttatgccc cataatatat tgcaatatat taggactcat
     3841 tcctttgtta gccatatttg tacagagtgt atgcctaaag gtatgtggcg taatctttgg
     3901 tagcttgtcc tcatgggtct tattatactt cttgactaac gctcttaaca tgctttgata
     3961 atgagttgct tgttttggta atccatcttg tttaagaaat aggaagttct ggtaaccatc
     4021 aacaatgatt ggttctgctt tagcgttctt acgccgttcc acgatacgtt caaatgattg
     4081 ataagctctt tcagtcattg gaatttctcg cttaccctgt gtggtctttg gaacttctac
     4141 ataatagcca atcttagtat cactcaacaa ttgatggtct accataatgg ctttattttt
     4201 catatccaat tctaaagtca aaccgcataa ttcagaaatg cgtagtcctg tttctaagag
     4261 gataacaaca tcatcataat atttacaata agtcttatcg ctccccataa aggataataa
     4321 gcccatttcc tgttctggtg ttagagcgat ttttggttct gttgtatctt ccaaaacatc
     4381 acttaactaa aaattaaatg gattctttct aatacagtcg tcttgaattg ccatgaaaaa
     4441 cgacgctttc agtgagcgct tataattgtc aatggattta taagcacacc catcttcact
     4501 cattcggata gcccagcttt tagcgtctga taatttaacc atatcaatgc tttttgcacc
     4561 tagtgggtca ttgatagtat ctatattttg atttataatt tatacatttt tttaaaaaca
     4621 gacttttaac tgtaaagaat ctatgtataa acttagctat gttgtccgtg tatctacaaa
     4681 gaatcttgac gagctaaaaa ggcgttgtga tgaagtcaaa gacttttacg acgacttatc
     4741 aatcaagctc gtgcgtccct ttggggatat gttgggattg catggcgaat ttattcctgt
     4801 cagcaaacgt tacatcaatg attatattca atatgtcact tcggattttt tggctggact
     4861 tggttttgga gcgacacaaa cccttggcga acatgaggat atctatcttg gctacaatct
     4921 ggacactgga aagaatgtct atctaaaacc tgcccttgct agtcaagggg taaagggttc
     4981 tattaccaat gcgttagcgt ctgcgtttat cggttcattg ggtggtggta aattattcag
     5041 taacaatatg cttgtttact atgcggtact attcggcgga caggcggtca tagttgaccc
     5101 taaagcagaa cgcggcaaat ggaaagaaac gctaccagaa atagcccatg agataaacat
     5161 tgtcaattta accagtaatg atgaaaacaa aggattgctt gacccttacg tcattttgag
     5221 ccgtaaaaag gattctgaaa gtttagcgat tgatatccta acattcctta ctggtatctc
     5281 cagtcgtgac agtgataagt ttttgcagaa aaatgacaac tggaaaataa taatggaata
     5341 gtttctatgt aaatatattt ttactatctt acctaactaa ttgaaagatg atataattta
     5401 atcaaagatt tggtaaggag ggatgaatat gcatttaatt gattttatga atgaagatat
     5461 taaaaagaag cttgttaaaa aaacgtataa aaagaaagag actattcttt ttgctgagca
     5521 agaaaatgaa tatgtaattc ttatgattga cggtattgca gaagcattca tcttaaatgt
     5581 gaaaggaaac atctcaacga ttcatcttta tagaagtggt agtttttttg gagaaatgga
     5641 acaatttaat gatgggaaaa aacccgttga aattgtcgct ttcacagatt gtaatgtata
     5701 taaacttcat agagatgatt ttttaaactg gttaagggga gattttgaag ctacaaaatt
     5761 tctgattcga gaaatatcta gtaaattagt tgtaaatgct gaattaattg aagaattatc
     5821 atctttaagt gttaaagaac gacttctgag gtgtatatcc ttacactatt atagaagtga
     5881 attaaatctg cttaccaaaa aacagcttgc tagcgaagta aacgctccaa ttagaagcat
     5941 taatcgtgct ataaatgaat gtgtacaaga acatctaatt gcttatgaaa acaaaagatt
     6001 tagtgtaatt aatcagcgag aggtattaaa gaatcttcct acaacataag tataatttca
     6061 aaaaagtatt gaataataat tattcaatgc ttttttattt cgggtcaagt gacctatttt
     6121 tttttatttc ttcattatat aatactccta tgcataatta tgttggattg atagctaata
     6181 aaagacagtg agaggtgtta tattatgact aaaacacaac agaaaatgat acaaaacgta
     6241 ttagaatttt caaaaagaga tagtaggata ataggacttg caattagcag ttcttatatc
     6301 acaaaatcgt tagatgaata ttctgatttg gattttctga ttgtagcaga tgataaatcc
     6361 tatgaagaag ttatcgaaga gagattactt attgtggaac agtttggaac attagtttct
     6421 gcttttactg gcgaacacgt tggagaacct cgattgataa tttccctcta tgattcccct
     6481 gttcttcatg ttgattttaa gtttacaacc ttagatggtt tactagatag ggttgaagat
     6541 tcagctattc tctatgaaga aaacaactgc ataacagaaa tttattctaa aaaagaagca
     6601 tacttcccaa ctccagactt acagtggatt gaagatagat tttggatttg ggttcattac
     6661 gcttgcacta agattggacg tagagaacta tttgaaacaa ttgatttttt atctttttta
     6721 agacaatcag tacttgcccc attaatacag cttctcttag gtaaattacc tcgtggagtt
     6781 agaaaaattg aattggacgc accccaatat attgaagcat tagaaaagac ggttgctaac
     6841 catgaatata aaagctgtgt taatgcattg caggctacta tcaacctgta tcttgagtta
     6901 agagaggaat tatcacaaag tcctattgtc cgaaaggttg aagctgaaag ggttgcatta
     6961 cagtattttc aagatttaat caaataaacc caaagtaaaa aaatattgaa tagtaaatat
     7021 tcagtgtttt ttcatttttg gtcaaatgac ctagattagt tgttgtaaca attctataat
     7081 tattttgaaa gtaacagtat ggaggataac tatgagtgat attttaagta gaattacaaa
     7141 taaaattggg gataagaata tagttgataa gttatcagct ctatcaaaat cagatttgaa
     7201 ctcacttcta ttagaagtgt ttgatagaca agcaaatact ttaactgcaa ctgatattct
     7261 aaagtcatac caactaaata gatttactat ccctagcggt atagatccag aagaaattca
     7321 tgctttggaa tcaaaattat tgagaaaagc attcaatatg gatatcaaga cgattatgct
     7381 ttctccctct gccccattag gtagctgtag cgtttttggc tccgtagatc aatataacgt
     7441 agtaagtgct ctacgaggga cagaaacact tgcagacccc tcaaatatgt tggcaataat
     7501 tattgctgat aaattaaaaa gaaaagaaga aaataatacc atacctatcc acatggctac
     7561 tactgctagg gtaataagag cacaaaattt tgtaggtaaa ggtttatatt cacattttgg
     7621 cttatattgt atggtttcat ctggtataga tacagggtct tacacttgtg aaaaaatgtt
     7681 gttagaaaag cacttaaact attataaaga tatattaagt gaaatagaaa atgttcgttt
     7741 ctctattatt ctacgcaaaa gaaacggata caaagataat gacggatttt tcgacagaat
     7801 ggttgaaact atcaaactta tttttcctaa tatagagtta tcaattcata atgatgatgt
     7861 tgataataat tattataaag gtatcaattt caaattatcg gtcaaacaag gaaatgaaac
     7921 cgttgaaata gttgacggtg gatttgttga ctggacttat caaatgcttg gaaataaaag
     7981 agaacgctgt ttgataagtg gtattggctt agaaagattt cttgtagctg tttcataaaa
     8041 ggagaagaaa aatggaactt atagagtgga attatgctta tattaccgat ttagttgagt
     8101 ttgcgaatga taaagaaatt gcaaagaatc ttcgtgacaa cttcccccac ccttataggg
     8161 agcaaaacgc tagagatttt gttagttttt gtttggcaac ttcagatgtt aaacaactta
     8221 gctatgctat tttttatcaa gaaagggcta ttggaagtat cagcctaaca tttgaagaag
     8281 atacctctat taataaaaat gctgaattag gttactggct tgctaggaac tattgaggca
     8341 aagggatagc aacaaatgca gtaaaagaaa tatgcaaaat tgcctttgaa aaatacaacc
     8401 ttaacaaaat tcatgctaat gtatattcct acaatagaga gtcaagtaaa gtattggaaa
     8461 aatgtggctt taagattgaa gaatactgtc acaattcata ataaagaata gaaacatgat
     8521 tgattgccat gtatatagtt taattcgacc gcaatagcat ttattagaat taacctactt
     8581 tttaataaca gaataagttt ttcccctcta ttaatttctt atgcatcttt gtatttttat
     8641 gaaaagctag ccaatgcata tttccataca tcaatatggt ggtggcttac aaccaatata
     8701 aattaaatac gttttaaaga atacacattt ttgccctata ggcagagtgt gtattttttt
     8761 ctcttttttt tgaaatttat cgaagattta acgccctccc accgtgatag gagtaagcaa
     8821 ggttatttaa ctccttgcga tggaaagagg gtgaaatctt atggttgatg aaaagacaat
     8881 tgaacatcaa ttcgacagtt tctgtaaaac agttttgcgt aactatgcta gagatattta
     8941 tgacgaaaat aaacgcagaa atgattattt ggtatctctc gaatctttgt cacttgcaga
     9001 attaagtaaa ttgagtattt tagatgatta tgattctaac tacatctgta tggtttctta
     9061 cgactacaac atacgaattg aagatgtatt aatggcgcaa gcaatcggaa aacttacaaa
     9121 aagaaaacaa gatataattc tactttcatt ctttttcaac atgacaaatg ctgacatagc
     9181 aacattgatg gatttagcag aaaataccat acattatcac aaaacaaatg cactaaaaga
     9241 gttgaaagaa ctcatgcagg aacattgaaa tgaaacctac taaagaagta ttacctttta
     9301 caattatttt acttgctgta catggcgatg taaatgcaat aaacgtaata cttaaacatt
     9361 ttgaacacta tatcattcgt ctttcacaga aaactttatt tgatgaatac ggaaatccct
     9421 atattcatgt agaagaagaa acaaagcgaa tgctaggaac aaaactaatc actgctattt
     9481 tgagatttaa tttgtcttaa tctcgccctc tctccatgta tcaagctatt tggtacatgg
     9541 agaatcacta attatttgtc tataaaagcc cacaagctat tgtgattttt tataggcaaa
     9601 tcaatgccga ctgttctttg acaactgaat aaagtagata gatacgtttg tgatacagat
     9661 agccaacaaa tactatacgc catgacctta atcaagagag ctactatata gtgatttgtg
     9721 aataaccttt ggaacggttg ttttgccgta acctgtacca cagtataatg atacacctgt
     9781 atgacacggt tctgtccata agaatgggat tggttgaaat accaatggag cttatcaaag
     9841 ccatctatct acttctgaac tacgaacata gaaaggagtg atacattata tgaacaatac
     9901 tgatgtacct atttgggaaa aatatacctt gacgattgaa gaagcgtcaa aatactttcg
     9961 tattggagag aaaaaattac gtaaacgtgc tgatgaaaac cttgattctg gctgggtcat
    10021 tatgaatagc aatcgcattc aaataaagag aaaacaattt gagaaaatcg ttgatacact
    10081 tgacgttatc taatgaaatt gagccttata tgttataata ttcatatgac gtatcaagct
    10141 caattcggtt attgagagga gcttcttatc atgtcaactg aaaaaagacg agataataaa
    10201 gatagaattt taagaactgg agagagccag agaaaagatg gaagatacgc atataagtat
    10261 gtatattcat ttggtaaacc acaatttgtt tactcttgga aacttgtacc tactgataaa
    10321 cccccaaagg gaaaacgtga tgatatatca ttaagggata aggaaaaagc aatacaaaat
    10381 gaccttgatg atagcattga cactattggt aagaaaatga cagtttgtca gttatacgct
    10441 aaaaagaatg gactaagaaa gaatatccga cttaacacta aaaaaggacg ccattatctt
    10501 atgaagattc ttaacaagga gtgattctgt gaagagatgt attgtagtag tggaatagtc
    10561 aaaaacataa tatatattaa aggagagatt taaatatgac tattccaagt tcaaataagg
    10621 tatatccaag aagtaatgat tatcaaactg tatatcttaa aaatgtaata acaagggaaa
    10681 atatagaagt tggagattac acaatatata atgactttta taatgaccca agagattttg
    10741 agaaaaacaa tgtattgtat cattacccta taaacaatga taaattaata attggtaagt
    10801 tttgctcaat agcatgtaat gcaaaatttc taatgactag tggaaatcac tcaatgaaat
    10861 caaaatccac atatactttt cccatctttt atgaagaatg gaaactcgat atcaaccata
    10921 taacggacgc ttgggacaat aagggtaaca ttataattgg aaatgatgtg tggataggtt
    10981 atgattctat aattatgtca ggtgtaaata ttggtgatgg tgcaattatt ggaacaagag
    11041 cagtagttac taatgacgtt ccaccgtatt ctattgttgg aggagtacct gcaaaaatta
    11101 taaaaaagag atttaataat gatacaattt caaaattatt agaaattaaa tggtgggatt
    11161 ggccatataa aaaaattcaa tcaaacatta agcatattca atcaggaaat attgataaat
    11221 tagtttaata ttttataatt tatttatatt aaactttact ttaataatca ttttataaga
    11281 gctttttcaa aatttgtata ttattttaat atatataaat ttaatacaac attaaataaa
    11341 ataaaaagta aagttactta ataaaaagtt actttacttt ttattattta aattcctgtt
    11401 tttattataa taggtaaaat tctattaaac tagttcacat tttcattatt attgatatat
    11461 tatatatgaa tataccattt tgttttttaa taaaaaatca tgctacatca atagtaagca
    11521 actattaatg tagcatgatt ttttgtatct aaataatctt agtatttacc tatcagtata
    11581 gattgatata tcaaaaacta tagtcttcta tattcttctc tttttagctt ttggttactt
    11641 agatagtaat caatttcatc aattagacgt tgtttatcat caggtaatac accttttaaa
    11701 ttagcataat ttgatgcatg attacttcta aatacaattt tttcattagc atctatattc
    11761 tttatcatct ctttaatttc ttgtaacaca gccttatcct ctagtattgt aaactctcct
    11821 gccttaagta aatcgtaaag ttcagtatta ggttctacca ttaaactaag tacacccaca
    11881 taatctggtg aaattgctcc tagcattttt cctgtatcaa ctgcatgctg atgtgttttt
    11941 ttagttcctc caagacctgc tattacagtg gctgataatt taatcccact ttttttaact
    12001 tttctaccaa cttttattaa ttgttcacta ctaaaacctt tcttaatatc ttctaatact
    12061 tcattgcttc cactttcaag ccctagataa atcattttaa caccaagttt tcttaattct
    12121 ttaagttcat catcagattt tttctctata gatttaggag agccgtacat agtaattctt
    12181 tcacactctg gaaaaacttc ttttatatat aaaataatat ctcttaattt ctccattggt
    12241 attatcaatg catctccatc tgctaagaat attctttcta catgcttata atatcttcta
    12301 aatatatcaa tttcattttt tattacttct agtggcttta ttttaaattt tttagatttg
    12361 tacatactac aaaacgtaca tttgttatga gaacatccta gtgtgacttg tattataaga
    12421 ctataagcct cacttggtgg tctgtaaagt ggcatatcgt attccatatt aaaatccccc
    12481 ttgtaataaa atattcattc tattatatta ttaatattta ctttaaataa taacttataa
    12541 aattatattt tttaaatttt agtttaagat atattcttta aaaatttaat gatactattg
    12601 gcagtaatat taagttgttt ttcttgactt ataatagcat cattatctcc cttttgtttt
    12661 ccataatctc caaattgtgc atgatttcct ccttcaatct caacataagt tgtatcatca
    12721 ggaagttttt gttttgattc tacaagactt ttaaaattga ctactccatc tttgctcccc
    12781 catatagata taactttttt tcctaattct ttcaactcat cacccattgg ataagaagct
    12841 aaaaatacaa cgccttcaat taatttatta tcacgtgcaa aatttgatgc tgcaactcct
    12901 cctaatgaat gacctcctat tacccaatgt tctatgttgt tgtaagaatc cataactttc
    12961 tgtgccttat tagttccaag tatagctaga ttaagtggca tctttacgat tacaacttca
    13021 tatccacttt ctgctatttt tcttgcaagt ggagcataag attctatttc tactttagct
    13081 cctggataca aaattaaacc tttagaaact tttcttcctt ttggtgtaaa tgaaatgttt
    13141 tcatttacag ttacttcaac tttactattg ctgactagag cttcttttgc cagcttttga
    13201 ggttcatatg ttttatttat ccatatgaaa aagccaagca aaatcaatac aaatagtata
    13261 cctattccct taaatatctt attctttatg ttaaattttc tattattatt tttatcatct
    13321 ttgttctcaa cctcatcata aagtaaaggt ctctcaagtt ccatagttat actaaatgta
    13381 tcatatttct tattacgctt tacctttaca tctttactca taaatctaac ccccataata
    13441 tttgaatact attatagttt atcctaagta aattgttttt tcaaccaatg aaaaaaatca
    13501 atattttaac tattttcata taaaattcat aaatatatgt tttttgtttt ttatatatta
    13561 ttttctttta gtattttata aaacaaatag ccatatactt tattttaaat atatggctat
    13621 tctataattt aatatctaag ctgcttcttt tattgaaact ttagttatat tacttattct
    13681 atacatttct ttgacaccat ttagagtttg cagtaagttt agacatatta tcttgtcacc
    13741 tagactttta gtatttataa tactctctaa aattacactt cttccttcat catacttatc
    13801 tacattgtaa tttgaaatat aattagtatc tctcaatatt ttttcaacat cttcatcttt
    13861 tattttattt ttattaacat ttatatatag attatacata ttacttatta gtaatttctg
    13921 attttctaaa aaatcctctt gatgtttatc tttatatata gcatttatca acataagtct
    13981 atcttcaata agtgatggta tcaataataa attttttata tagtaaacat cagctacatt
    14041 ttctatagac ttattgactt catcaattat atttttaact attcctttat acatttctat
    14101 aacatgttga tagcctgttt tagcatcata tggtaatata aacttattta ctattaatgc
    14161 aataattgct cctaatgcta catatgaaat cctgcttatg gttaaaacat ttgggtctcc
    14221 cataactact gctgaaccaa gagctgaaac agttacacat accattaatt ttctataatc
    14281 aactacataa gagtttatat accctgctaa aagaactatt aacgacctta atgtactatc
    14341 ttttattatt gaaaataata caataaatat tacagctcct ataaatgtac cttctattct
    14401 ttttctagac ctttgtatac aattttctgc gtaaggttgt gttaatgaaa agacagttaa
    14461 cattatccat cttccatctc ttaaatggaa ataatccata ataaaacccg ctacagctgt
    14521 agctaaagca atctttactg cataagaaaa tcttatagaa tttaaattaa agtttttctt
    14581 atatattgat agtcgtttaa attcatgagg tatctttgat tttctttcag ctttcttttc
    14641 gtctcttgat tttacttttt tataatctac taaaaactca tataaatttt ctaaaacact
    14701 ataaatttct tttaaattta tatttttagt atcctgagca ataacataat ctctaaatcc
    14761 taatatctct ttatcagtta tggtatcttt attttctaaa cacatcttaa tatagtttat
    14821 ttctttcgtt gctacaacta gaacatctga
//
LOCUS       DAFAZV010000193        13587 bp    DNA     linear   BCT 13-OCT-2021
DEFINITION  TPA_asm: Clostridioides difficile isolate L;13.7548710.S
            SAMN05207715-rid12391623.guided.078, whole genome shotgun sequence.
ACCESSION   DAFAZV010000193 DAFAZV010000000
VERSION     DAFAZV010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN05207715
            Sequence Read Archive: SRR3629297
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Clostridioides difficile (Clostridium difficile)
  ORGANISM  Clostridioides difficile
            Bacteria; Bacillota; Clostridia; Peptostreptococcales;
            Peptostreptococcaceae; Clostridioides.
REFERENCE   1  (bases 1 to 13587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JUN-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 05-JUN-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001059237.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001059237.1
            Genome Coverage       :: 79x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 06/06/2021 03:17:57
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 4,269
            CDSs (total)                      :: 4,178
            Genes (coding)                    :: 4,103
            CDSs (with protein)               :: 4,103
            Genes (RNA)                       :: 91
            rRNAs                             :: 9, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 9 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 75
            CDSs (without protein)            :: 75
            Pseudo Genes (ambiguous residues) :: 0 of 75
            Pseudo Genes (frameshifted)       :: 33 of 75
            Pseudo Genes (incomplete)         :: 37 of 75
            Pseudo Genes (internal stop)      :: 20 of 75
            Pseudo Genes (multiple problems)  :: 12 of 75
            CRISPR Arrays                     :: 8
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13587
                     /organism="Clostridioides difficile"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN05207715-rid12391623.guided.078"
                     /isolate="L;13.7548710.S"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1496"
                     /country="United Kingdom: Leeds"
                     /collected_by="ModMedMicOxford"
     gene            246..863
                     /locus_tag="KOU88_004259"
     CDS             246..863
                     /locus_tag="KOU88_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009902665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBK3214022.1"
                     /translation="MCKKTYLLVVSMLIAGLLTACSGSPTKDSGQAQDNTKKEANASN
                     NALKDEKNNENLMEQDFKVPYTDAINIFKDKYKDADIVDLSLERDLNKFVYTVEGVDD
                     NNEYKMKIDANTKDVLEDKTEKLDSEDLNGVARKEKLDLNDIMTPQQAMEIALKEQNG
                     IVKEWSLDKDLDVTFYKIRIDKDKNEYDIKVDSKKGTVLKVEKED"
     gene            971..3502
                     /locus_tag="KOU88_004260"
     CDS             971..3502
                     /locus_tag="KOU88_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003420250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK3214023.1"
                     /translation="MSLKSLKIKENLYWVGSLDPDLRVFDIIMYTPYGTTYNSYVLKG
                     TEKTVLFETVKDKHFDNYIERLNDLNIDFEKIDYIVVSHTEPDHAGSVEKLLDLAKNA
                     KVVASETAIKYLKEIVNKDFEYVAVTDGDTLSIGDKTLEFFSVPMLHWPDTIYTYIKE
                     DKTLVTCDSFGSHYSNDKIVNTLDENEEKDYLDALRYYYDCIMGPFKPSMVTAIEKIK
                     DLDIDTVCPGHGPVLTENPRKIIDLYYNWSVNEQIKLEKEVTICYVSAHGYTKIMAEA
                     IKAYIEKNSNYKVNLFDVIEHKQEDILAKIAVSQGVLFGTPTILGDALKPIWDILISL
                     NPVLHGGKVASVFGSYGWSGEGIENAMERISQLRMTAVKPFAVNFKPSNEEIDKLYSY
                     TGKFLDKLNSTFGSKKKTKKFKCVICNEVFEGDSAPSVCPVCGAKEDQFIEVEEDEVT
                     FRKDTDEYFVIVGNGAAGFYAADAIRKRNKTCKITMISNEDELTYYRPALSDGINEEL
                     GSDFYMEDKDWYDKNNIVVILGTNVDKLDEVNKTIIVNDGAIKFDKLVIATGSRNFIP
                     PIKGHDLENVFTLRNIKDLYSVKEALEKSKKVVVIGGGLLGLEAAWEFRLKGLEVVVV
                     EAMDSILSKQLDKEGSKILEQCVRDTGIDVRLGVAVDGIEGDGKAQKVVFKDGDSVDC
                     DMVVFSIGVRANTQMVQDTSVKIDRGIVVDKTLQTNVKDIYACGDVAQVGNISLAIWP
                     SSVEMGKIAGANASGDNLTFESEVYPVSLDAMNVKVFSIGNIQNFDKEISSKDEGQRI
                     YKKLFMKDGSLVGAILINDLSCTVKLIRLISEKGDFEDIMKADIL"
     gene            3936..4637
                     /locus_tag="KOU88_004261"
     CDS             3936..4637
                     /locus_tag="KOU88_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanG-Cd-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HBK3214024.1"
                     /translation="MNENILIVDDEKEIADLIEVYLKNEGFTVYKFYTGKEALECIES
                     KNLDMAILDIMLPDIDGFHICQKIREKYYYPIIMLTAKIEDIDKIMGLTIGADDYITK
                     PFNPLEVVARVKTQLRRYMRYNNSYEQQSIIVNEYDIKGLIINKETHKCSLFGKEVAL
                     TPIEFSILWYLCEHQGKVVPSEELFEAVWGEKYLDNNNTVMAHIGRLREKIHEPSKNP
                     KFIKTVWGVGYTIEK"
     gene            4687..5769
                     /locus_tag="KOU88_004262"
     CDS             4687..5769
                     /locus_tag="KOU88_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012816161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK3214025.1"
                     /translation="MRTALMAFIAIIFIWILYSFILYGKFSIWIVSFFENAFRMEYKA
                     ALNLYQQIFRNSMELFMILAMVIVFFIIFRVYLNWFTKYFSEINQGIDSLIKEDVGEV
                     ALSPELLAIEKKINSIKHILEQRKFETQMAEQRKNELIVYLAHDLKTPLTSVIGYLTL
                     LRDESQISEELRKKYLSISLDKAERLEDLINEFFEITRFNLSNISLEYSTVSLTRMLE
                     QLTYEFKPTLMSKNLKYTLNVTPNMMIRCDVNKMQRVFDNLLRNAVYYSFEDTTIEIT
                     AVQEDDYIKLKFINHSNTIPEEKLERIFEQFYRLDTSRNSNSGRAGLGLAIAKEIVEL
                     HNGTITAHSENNIIIFKVIIPIVGNL"
     gene            6030..7130
                     /gene="vanG"
                     /locus_tag="KOU88_004263"
     CDS             6030..7130
                     /gene="vanG"
                     /locus_tag="KOU88_004263"
                     /EC_number="6.3.2.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-serine ligase VanG"
                     /protein_id="HBK3214026.1"
                     /translation="MNNKKIAVIFGGNSTEYDVSLQSAFAVLENLNTEKYDIIPIGIT
                     REGNWYHYIGDYNNIQNNTWFERDTDIIPVIVSQNRVKNGIIEFLIPDAVSQNHIPNS
                     AIESCENDIKYTKLDFVFPVLHGKNGEDGTVQGLFELAGIQVIGCGTLSSALCMDKDK
                     SHKLVHSEGIKVPKSILLKYSDKFNVAELSKDLTYPLFIKPVRAGSSFGISKIYKKEE
                     LQVAVDLAFEHDNEVIIEENIDGFEVGCAVLGNDDLLVGRVDEIELSKGFFDYTEKYT
                     LKSSKIHMPARIDLDCEKRIQETAKIIYRTLGCSGFARVDMFLTPSGEIIFNEVNTIP
                     GFTSHSRYPNMMKGIGLSFEEILDKIIEVYIK"
     gene            7127..7933
                     /locus_tag="KOU88_004264"
     CDS             7127..7933
                     /locus_tag="KOU88_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBK3214027.1"
                     /translation="MMNNILLDKNKEDKMTNTILLTKDKVYDGNLILVNAFLPVKTSE
                     DIDLIPVDTRFPSILMKREATNILQNILKSICGINEIVPVSGYRTAEEQQDIYSSSLR
                     DNGKDFTKKFVALPNHSEHQTGLAIDLGLKKEVIDFICPEFPYNGICNEFRKAALHYG
                     FIERYQCKKEEITGISQEPWHFRYVGYPHSEIINKMNLALEEYIEYIKRFSYTNCLKI
                     EDKEKIIEIFYVPIHTKEEVRISIPEQCVYQISGNNKDGFIVTFWRNRKD"
     gene            7951..10089
                     /gene="vanT"
                     /locus_tag="KOU88_004265"
     CDS             7951..10089
                     /gene="vanT"
                     /locus_tag="KOU88_004265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021418922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine racemase VanT catalytic subunit"
                     /protein_id="HBK3214028.1"
                     /translation="MIRNKSYAGLDYFRIIAALLIIAIHTSPLLSYSKMADFVLTSII
                     ARIAVPFFFMLSGFFLISTYNYNCNKLKSFLKNVLFIYGIAIVIYIPLNIYTGYFSMN
                     NLVPNIIKDIVFDGTLYHLWYLPASIIGASIAYFLVKRLGLKYSLVITIVIYVIGMFG
                     DSYYGFLEKIPLLKNLYGYIFEVSDYTRNGIFFAPVFFILGGIISNKSNYMSTKNSLI
                     GFLISFLLMLCEGMFLHKLGVQRHDSMYIMLLPCMYFLFTALTFLKGSRARLLRTSSL
                     IIYIIHPMMIVVIRMFSKIFGIQTVLVDNSLIHYIVVSIASFIASIIIILILKPLKKD
                     LKGEHKVNTNRAWIEIDLNNLEHNVKMIQKAMPEDCELMAVVKANAYGHSAFEVATCA
                     NQIGVKAFAVATIDEGIDLRRYGILGEILILGYTNPIRAKELHKYNLTQSVIDLNHAI
                     SLNKQKYNIKSHIKIDTGMHRLGFDVNDVRSILKAFKLKYLDICGIFTHLCVSDSLKD
                     EDVDFTNKQIECFYKLIDFLLKKGIKIPKVHIQSSYGFFNYPNLKCNYVRIGIALYGI
                     LSSPNDTTKLQLDLRPVLSLKSQVILIRKIQKDDSFGYGRVFIASRDSVIAILSIGYA
                     DGIPRNLSCGKSYVIINGCRAAIVGRICMDQLAVDITDIPNVEVGNTAIIIGRDNLSE
                     LSASEVANNSCSISNELLSRVGRRLNVIKK"
     gene            10403..11023
                     /locus_tag="KOU88_004266"
     CDS             10403..11023
                     /locus_tag="KOU88_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBK3214029.1"
                     /translation="MQYIQELLDLTQNYWVLATIIGLLSAFIESFIPALPLVAIVTAN
                     AAIQGLFIGCLLSWIGSGLGTTSLFLLISRFNDSKLFNKLRNSKTEKAISWMDKQGFK
                     LLFIAYACPFMPGCLVTIASAFGKKDLKDFVPAMLAGKFVMFIVISYVASDIEGFITS
                     PLKIASFILLVFLSWKIGNRVNKNLENHNYDFHHKKHHNDKDDKMI"
     gene            complement(11189..11725)
                     /locus_tag="KOU88_004267"
     CDS             complement(11189..11725)
                     /locus_tag="KOU88_004267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009889535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBK3214030.1"
                     /translation="MIKETHERGGYIFALLILPFINNLYLVKYDIAYKIVLIIIYIYF
                     AYLGSLFPDIDMRGSYISKKFMLIYKLFGSRFRHRGFTHSLIALLLIYSFFKSLTIFT
                     NNNIVFSCLSSGFIIGYLSHLCLDLITKEGIELFYPITINISLLPIKTNSKTEKFISK
                     LLNFIVIFLIGYQFYILL"
     gene            complement(11838..12512)
                     /locus_tag="KOU88_004268"
     CDS             complement(11838..12512)
                     /locus_tag="KOU88_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBK3214031.1"
                     /translation="MSLFIISQCITSFAFTPENNKFKVKPLPYAYDALEPYIDKETMK
                     LHHDKHYQAYVDKLNAALEKYPELYNYSLCELLQNLDSLPKDIATTVRNNAGGAYNHK
                     FFFDIMTPEKTIPSESLKEAIDRDFGSFEKFKQEFQKSALDVFGSGWAWLVATKDGKL
                     SIMTTPNQDSPVSKNLTPIIGLDVWEHAYYLKYQNRRNEYIDNWFNVVNWNGALENYK
                     NLKSQD"
     gene            12715..>13587
                     /locus_tag="KOU88_004269"
     CDS             12715..>13587
                     /locus_tag="KOU88_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003436426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthetase B"
                     /protein_id="HBK3214032.1"
                     /translation="MDGNISIYYKGDISKKEDIKFKIKESVNNTRLSSRIEYKDEEKT
                     FDFERFNVIDAIYGNKPFEKDGKVIVFNGNIYNYHEIKEELIKKGHNFTTNDDIEVLL
                     ASYIEFGKNCVHKIKGMFNFIIYDRENESIFGARDLFGIKPLYYINKENAIIFSSEYK
                     FLLEYMKNLNINERSLQSYFSFQYVLPEDTMIQGIRLIPAGHYFRVENGILSLKRYNK
                     LEFRSSTKFFYTKNHLGNRDVNEDDIRNIVVDSIVTHMEEEKEIGTFLSGGIDSSIIT
                     TVASQINPNIKSFSA"
BASE COUNT         5191 a         1439 c         2332 g         4625 t
ORIGIN      
        1 caaaatgaac tttttagttc atgaggcact ctttttgtac gaaataaaat atatttttat
       61 tatttcaaca atgaaaaaga ggcttgtttc cattttgaga cagtataatt tttatgtaac
      121 tttaatttta gtaaatataa agttttaaaa ttgataaaat aggaggaatt tttaatataa
      181 aagggtaaat aaagggttta gagggcataa tatagaataa attaatatat ttaaggaggg
      241 tttttatgtg taaaaaaacg tatttattag tggtaagtat gcttatagcg ggtttattaa
      301 ctgcatgtag tgggagtcca actaaggatt caggacaagc acaagataat acaaaaaagg
      361 aggcaaatgc atcaaataac gctttaaaag atgaaaaaaa taatgaaaat ttaatggaac
      421 aagattttaa agtgccatac acagatgcaa taaacatatt taaagataaa tataaggatg
      481 ctgatatagt agatttaagt cttgagagag atttaaataa atttgtttat actgtggaag
      541 gtgtagatga taataatgaa tataagatga aaattgatgc taatacaaaa gatgtattag
      601 aagataaaac agaaaagttg gattcagaag atttaaatgg agttgctaga aaagaaaaat
      661 tagatttaaa tgacataatg acacctcaac aagctatgga aattgcatta aaagaacaaa
      721 atggaatagt taaagaatgg agtttagaca aagatttaga tgttactttt tataaaataa
      781 gaatagataa agataaaaat gaatatgaca taaaagtaga ttctaaaaag ggaactgtat
      841 tgaaggtaga aaaagaagat tagaagattt aaactatctt taaaataatt tcttttttga
      901 ataaattttg tttaaaatat aacaagcagg gtataaagag actaaataac tattttagga
      961 ggagtacggt atgtcattga aatcactaaa aataaaagaa aatttatatt gggtaggttc
     1021 gcttgaccct gatttaagag tatttgacat aattatgtat acaccttatg gaactactta
     1081 taattcatat gtattaaaag gaacagaaaa aacagtttta tttgagacag ttaaagataa
     1141 gcattttgac aattatattg aaagattaaa tgatttaaat atagattttg aaaaaataga
     1201 ctatattgtt gtaagtcata ctgaaccaga ccatgcagga agcgttgaaa agcttttgga
     1261 tttagctaaa aatgcaaaag tagtagcttc agaaacagca attaaatatc ttaaggaaat
     1321 cgtaaacaaa gactttgaat atgttgcagt tacagatgga gatacattat caattgggga
     1381 caaaacttta gaatttttct ctgtacctat gcttcattgg ccagatacca tatacacata
     1441 tataaaagag gataaaactc ttgtaacatg tgattcattt ggtagtcact atagtaatga
     1501 taagatagta aatacacttg atgaaaatga agaaaaggat tacttggatg ctttaagata
     1561 ctattatgat tgtataatgg gtccatttaa accatctatg gtaactgcta tagaaaagat
     1621 aaaagattta gatatagata ctgtatgtcc aggtcatggt ccagtattaa ctgaaaatcc
     1681 tagaaaaatt atagaccttt attacaactg gagtgtaaat gaacaaataa agttagaaaa
     1741 agaagttaca atttgttatg tttctgcaca tggatataca aagattatgg cagaagctat
     1801 aaaagcatat attgaaaaaa atagcaacta taaagtaaat ttatttgatg taatagagca
     1861 taagcaagaa gatattttgg caaaaatagc agtatcacaa ggtgtattat ttggaacacc
     1921 aacaatatta ggagatgcgt taaagcctat atgggatata ttaatatcgt taaacccagt
     1981 tcttcatggt ggaaaagttg cttcagtatt tggttcatat ggatggagtg gagaaggtat
     2041 agaaaatgct atggagagaa taagtcagct tagaatgaca gcagtaaaac cttttgctgt
     2101 taactttaaa ccatcaaatg aagagattga taaattatat tcttatacag gtaaattcct
     2161 agataagtta aattctactt ttggaagtaa aaagaaaact aagaaattta aatgtgtaat
     2221 ttgtaatgaa gtttttgaag gtgatagtgc tcctagtgta tgccctgtat gtggagctaa
     2281 ggaagaccaa tttatagaag ttgaagaaga tgaagttact tttagaaaag atactgatga
     2341 atatttcgta atagtaggaa atggagcagc tggtttttat gcagcagatg ctataagaaa
     2401 aagaaataaa acttgtaaga taactatgat ttctaatgaa gatgagttga cttactatag
     2461 acctgcactt tctgatggta taaatgaaga acttggttca gatttctaca tggaagataa
     2521 agattggtat gataaaaata atatagtagt aatattagga acgaatgtag ataaattaga
     2581 tgaagtgaat aaaactatta tagtgaatga tggagctatt aaatttgata agcttgtaat
     2641 agctacagga agtagaaact ttataccacc aattaagggc catgatttag aaaatgtgtt
     2701 tactcttaga aatataaaag atttatatag tgtaaaagaa gcactagaaa aatctaagaa
     2761 agttgtagtg attggtggcg gtttattggg acttgaagct gcatgggaat ttagactaaa
     2821 aggattagaa gtagtagtag ttgaagccat ggatagcata ctatcaaaac aacttgataa
     2881 agaaggtagt aaaatattag aacaatgtgt aagagataca ggaatagatg taagattggg
     2941 tgtagcagtt gatggtattg aaggtgatgg aaaagctcaa aaagttgtat ttaaagatgg
     3001 agatagtgtc gactgtgata tggtagtatt ttcaattggt gtaagagcaa acactcaaat
     3061 ggttcaggat acatctgtaa aaattgatag aggtattgtt gtagataaga cattacagac
     3121 aaatgttaaa gatatatatg cttgtggaga tgttgcacaa gtgggaaata ttagtttagc
     3181 aatatggcca tcttcagtag aaatgggaaa aatagcaggg gcaaatgcaa gtggagataa
     3241 tttgacattt gaaagtgaag tatatccagt ttcattagat gcaatgaatg taaaagtatt
     3301 tagtattggt aatatacaaa attttgataa agaaatttca tcaaaagatg aaggtcaaag
     3361 aatatataaa aaattattta tgaaagatgg ttcattagtt ggagctatac ttataaatga
     3421 tttaagctgt actgttaaat tgataagatt aatatctgaa aaaggtgatt ttgaggatat
     3481 tatgaaggct gatatactat aatttaaata cattaaaata aaaaggagtt gtctcaaaat
     3541 tgattttttt ctaatcaaat tttaaattca actccttttt tgaattttta tataaaataa
     3601 catggaaatt ttagtaatgt ctgtggttac atacataggt ttaattgttt tttatatgga
     3661 ttgtctctgg tataataaat tgaattgtgt ttgactgata gatattttta ttgaaagtta
     3721 atacctgtta tgcgataata aggacgtgtt aggggagttt ttataataac aattaatctc
     3781 agtttttgtg ttccaatagt agcatcaaca cattctgatg tagtagttct tttcttataa
     3841 aaattagtta caaatatgct tgtaattatt tgatatgtaa atttaccaat attataaatg
     3901 atgacctcga taataaggag agtgaaaaat aatctatgaa cgaaaatatt ttgattgtgg
     3961 atgatgaaaa agaaatagca gatttaattg aagtatattt aaaaaatgaa ggttttacag
     4021 tatacaagtt ttatacaggt aaggaagctc tagaatgtat tgaatctaaa aatttggata
     4081 tggctatttt agatattatg cttcctgata ttgatggatt tcatatttgc cagaaaattc
     4141 gagaaaaata ctattatcct atcattatgt taacagctaa aattgaagat atagacaaga
     4201 taatgggttt aaccataggt gctgatgatt atataacaaa gccatttaac cctttggaag
     4261 ttgttgcaag agtaaagaca caattaagaa gatatatgcg atataataat tcttatgaac
     4321 aacagtcgat aattgttaat gagtatgata ttaaaggatt gattatcaat aaagaaacac
     4381 ataaatgtag tttatttggg aaagaagtag cattaacacc gattgaattt tctattcttt
     4441 ggtatttatg tgaacatcaa ggaaaagtgg ttccttctga agaattgttt gaagctgtat
     4501 ggggagaaaa atatcttgat aataataaca cagttatggc tcatataggg cgattacgtg
     4561 aaaaaattca tgaaccttct aaaaacccga aatttataaa aactgtatgg ggagtaggtt
     4621 atacaattga aaagtaaaaa tattaaagtc aatcctgact ttactcaagt gagaaataaa
     4681 atttttatga gaacagcttt aatggcattt atagccatta ttttcatatg gattttatat
     4741 tcttttatat tgtatggtaa gttttctatc tggatagtat cattctttga aaatgctttt
     4801 cgtatggaat ataaagctgc attgaattta tatcagcaga ttttccgtaa tagcatggag
     4861 ctcttcatga tactagctat ggtgattgtg ttttttataa tattccgggt ttatttaaat
     4921 tggtttacaa aatattttag tgaaataaat caaggtattg actctcttat caaagaagat
     4981 gttggagaag tggctttatc tccagagtta ttggcaatag aaaagaaaat aaactcaatt
     5041 aaacatatac ttgaacaacg taaatttgag acacaaatgg cagaacaacg taagaatgaa
     5101 cttattgttt atcttgcaca tgatttaaaa acaccactta catcagttat agggtatctg
     5161 acactacttc gagatgaaag tcagatttct gaagaactgc gaaaaaaata tttatctatt
     5221 tcgttggata aggcagagcg tcttgaagat ttaattaatg aattctttga aattacaagg
     5281 tttaatttat caaatatatc acttgaatac agtacagtaa gcttaactcg tatgcttgaa
     5341 caactaacat atgagtttaa acctactttg atgagtaaga atttaaaata tacactgaat
     5401 gttacaccaa atatgatgat aaggtgtgat gttaataaaa tgcaacgtgt atttgataac
     5461 ttattacgaa atgctgttta ttatagtttt gaagatacta ctattgaaat aacagctgta
     5521 caggaggatg attatataaa gcttaaattt ataaatcata gcaatacgat tccagaggaa
     5581 aaacttgagc gtatttttga acaattttac aggttggata catctcgtaa ttcaaacagt
     5641 ggtagagctg ggttgggact tgctatagct aaagaaatag tggagcttca taacgggaca
     5701 ataacagctc atagcgagaa caatataatt atctttaagg ttattattcc gattgtagga
     5761 aatttgtaag aatttaagta taaaaaaata ggaaattctt taggataaat aaataaagag
     5821 cactcttgtt attgatataa ttactgtatc aaaacaagag tgcttttatt ttgatacagt
     5881 aattatatca atagaaaaat gtgaaaatat attatgtgga acagatgcaa ttgtaagtga
     5941 aggttgattg gatttgaaat agaaaaagta ttttaacatg tttctgtaga ttgtataaaa
     6001 ataaataaat caacaaagga gaatcaaaga tgaataataa aaaaattgca gttatatttg
     6061 gtggaaactc aacagaatat gatgtatcat tacaatcagc ttttgcagta cttgagaatt
     6121 tgaatacgga aaaatatgat attataccaa ttggaattac aagggagggt aattggtatc
     6181 attatattgg agattataat aatatccaga ataacacttg gtttgaaagg gatactgata
     6241 taattccagt tattgtttcg cagaaccgtg tcaaaaatgg tattattgaa tttttaattc
     6301 ctgatgctgt ttctcagaat catattccaa atagtgctat tgaatcatgt gaaaatgata
     6361 ttaaatacac taaacttgat tttgtgtttc ctgtactgca tggaaaaaat ggagaagatg
     6421 gaacagtgca ggggttattt gaattggcag gtatacaggt tataggatgt ggtactcttt
     6481 cttcagcatt atgtatggac aaagacaaat cacataaact tgttcattca gaaggtatta
     6541 aagtaccaaa atcaatatta ctaaaatact cagataaatt taatgtggct gaactgtcaa
     6601 aagacttaac ttatccatta tttataaaac ctgtgcgtgc aggttcatca tttggtatta
     6661 gtaaaattta taaaaaagaa gagttacaag tagcagtaga cttggctttt gaacatgata
     6721 atgaagtaat aattgaggaa aatattgatg gttttgaggt agggtgtgca gttttaggaa
     6781 acgatgactt acttgttgga agagtagatg aaatagaatt gtcaaaagga ttttttgatt
     6841 atacagaaaa atatacattg aaaagttcaa aaattcatat gccagctaga attgatttgg
     6901 attgtgagaa aagaatacaa gagacagcaa aaattattta tagaactctt ggatgttctg
     6961 gatttgctag agtagatatg tttttaactc catctggtga aattattttt aatgaagtca
     7021 atacaattcc tggctttact tctcatagtc gttatccaaa tatgatgaaa ggtattggat
     7081 tgtcttttga agaaatattg gacaagataa ttgaggtgta cataaaatga tgaataatat
     7141 tttattagat aaaaataaag aagataaaat gacaaatact atcttattga ctaaagataa
     7201 agtttatgat gggaatctaa ttctagtaaa tgctttttta ccagttaaaa catctgaaga
     7261 tatagattta attcctgtag atacaaggtt tccaagtatt cttatgaaac gtgaagctac
     7321 aaacatttta caaaatattt taaaaagtat atgtggaata aatgaaatag tacctgtaag
     7381 tggatatcgt actgcagagg aacaacaaga tatatattca agttctctgc gtgacaatgg
     7441 aaaagacttt actaaaaagt ttgtagcact tccaaatcac agtgaacatc agacagggct
     7501 tgctattgat ttagggttaa agaaagaagt tatagatttt atctgccctg aatttcctta
     7561 taatggtatt tgtaatgagt ttcgtaaggc agcactacat tatggtttta tagagcgtta
     7621 tcagtgtaaa aaagaagaaa taacaggaat atctcaagaa ccatggcatt ttcgttatgt
     7681 gggatatccg cattctgaga ttatcaataa aatgaatctc gctcttgaag aatatataga
     7741 atatattaag agattttcgt atacaaattg tttaaaaata gaagataaag aaaaaattat
     7801 agaaatcttt tatgtgccta ttcatactaa agaagaagtg agaatctcta tacctgaaca
     7861 atgtgtatat caaatatcgg gtaacaataa ggatggtttt attgtgacat tttggagaaa
     7921 tagaaaggac taagaaatgg aggaacaaga atgattagga ataaatctta tgcagggctt
     7981 gattatttta ggattatagc tgcattactt ataattgcaa ttcatacatc tccattatta
     8041 tcatatagta aaatggctga ctttgtgtta actagtataa ttgctcgtat tgctgtgcca
     8101 ttctttttta tgctatcagg cttttttcta atttcaacat ataattataa ttgtaataaa
     8161 ctgaaatctt ttctaaaaaa tgtattattt atttacggga tagctattgt aatttatatt
     8221 cccttaaata tttacactgg atatttttcc atgaataatt tagtgcccaa tattattaag
     8281 gacattgtat ttgatgggac tttatatcat ttatggtatc tacctgcatc aattattggt
     8341 gcaagtattg catactttct tgtaaaaaga ctaggtttaa agtactcact agtaatcact
     8401 attgttattt atgtaattgg tatgtttggt gatagttatt atggtttttt agaaaaaata
     8461 ccactattaa agaatttata tgggtatatt tttgaagtat cagattatac acgaaatggt
     8521 atattttttg cacctgtatt tttcatactt ggtggaataa tatctaataa atctaattat
     8581 atgtcaacta aaaatagctt gattggattt cttatatcat tcttacttat gttatgtgag
     8641 ggaatgtttt tacataaact aggggtacag cgtcatgata gcatgtatat tatgttattg
     8701 ccatgtatgt atttcttatt tacagcctta acatttttga aaggttctcg agctaggtta
     8761 ttgcgaacat catcattaat tatttatatt atacatccta tgatgattgt tgttattcgt
     8821 atgttttcta aaatattcgg aatacaaact gtcttggttg acaatagcct tattcattat
     8881 atagtggtaa gtatagcatc ttttatagct tctataatta ttatattgat tcttaaacct
     8941 ctaaaaaaag acttgaaagg agaacataag gtaaatacca atagagcttg gattgaaatt
     9001 gatttaaata atttggaaca taatgtaaag atgatacaaa aagctatgcc agaagattgt
     9061 gaattgatgg cagttgtaaa agctaatgcc tatggtcata gtgcttttga agtagcgact
     9121 tgtgcaaacc aaataggtgt aaaagcattt gcagtagcaa caatagatga ggggattgat
     9181 ttacgtcgat atggaatact aggagaaata ttgattcttg gatatactaa cccaataagg
     9241 gcaaaggaac ttcataaata caatcttaca cagagtgtta ttgaccttaa tcatgctatc
     9301 tctttaaaca aacagaaata caacataaaa tcacacatta aaattgatac aggtatgcac
     9361 agactgggtt ttgatgttaa tgatgtgagg tcaattttaa aggcatttaa attaaaatac
     9421 ttagatatat gtggcatatt tacacacttg tgtgtttcag atagtctgaa agatgaagat
     9481 gtagacttta caaataaaca aattgaatgt ttttataagt taattgattt tctgttaaaa
     9541 aaaggtataa aaattcctaa agtacatatt caaagtagtt atggtttttt taattatccc
     9601 aatcttaagt gtaattatgt aagaattgga attgcattat acgggatatt aagttctcca
     9661 aatgatacga ctaaattgca acttgattta cgacctgttt tatccttaaa atcacaagta
     9721 attcttatta gaaaaataca aaaagatgat agttttggat atggaagagt ctttattgca
     9781 agcagagata gcgtaattgc tatattatct attggctatg ccgatggtat acctagaaat
     9841 ttatcctgtg gaaaaagtta cgtaataata aatggttgta gagcagcaat agtgggtcga
     9901 atttgcatgg accaacttgc tgttgatatt acagatatac ctaatgtaga agttggtaat
     9961 acggcaataa taataggaag agataattta tctgaattat ctgcttctga agttgcaaat
    10021 aactcatgta gtatatcgaa tgaattattg agcagagtag gaagaaggtt aaatgttata
    10081 aagaagtaac tcaattaaat agtaatattt gttgtactgt gtaatttatt ttactctgac
    10141 tagacatttt tagtaatatt atgtctaata tatatttttt ataacttaca tgacaattta
    10201 agttataaaa aggtgatgtt tcagattttt attttgaaac atcacctttt ttgttataat
    10261 atataataaa ataattatac cttaactgta aacttatata gattatttac tttttaatat
    10321 tagattcatt ttttgagatt ggtatataat aaacatatag agtatataat aatagttaaa
    10381 gttaaaaaag gggaaaagca atatgcagta tatacaagaa ctacttgatt tgactcaaaa
    10441 ttattgggtg ttagccacaa taatcggctt attaagtgca tttatagaaa gctttatacc
    10501 agccttacca cttgttgcta tagttacagc aaatgctgca atacaaggat tatttattgg
    10561 atgtttgtta tcatggattg gctcaggact tgggacaact tcattattct tattaataag
    10621 cagatttaat gatagtaagc tttttaataa gttgagaaat agtaaaactg aaaaagcaat
    10681 aagttggatg gataaacagg gatttaagtt attatttata gcgtatgcct gtccatttat
    10741 gcccggttgt ttagttacta tcgcatcagc ttttggtaaa aaagatttaa aagattttgt
    10801 gccagcaatg ttggcaggaa aatttgtaat gtttatagtt ataagttacg tggcaagtga
    10861 tatagaaggt tttataacaa gtcctttaaa gatagcatca tttatattat tggtgttttt
    10921 gtcatggaag attggaaata gagtaaataa aaatcttgaa aatcataatt atgatttcca
    10981 tcataaaaaa catcacaatg ataaagatga taaaatgatt tagcttgtac gaaataaaac
    11041 gtatcttaaa atgatttagt actaaattat tttaagatac gttttatttt ttgtattaag
    11101 gtacaaaatt tttagttctt ttgtaaacta aaatatataa aacttattta tacttagttc
    11161 aaaatattgt tatttatttt ttctacaact ataataaaat ataaaattga tatccaatca
    11221 aaaaaataac tatgaaattt aatagcttag atatgaattt ttctgttttt gagttagttt
    11281 ttataggtag taaagaaatg tttatggtaa tgggataaaa caattcaata ccttctttag
    11341 taataaggtc aagacacaag tgagatagat atcctattat aaacccactg gacaaacatg
    11401 agaaaactat attattgtta gtgaagattg tcagagattt aaaaaaacta taaataagta
    11461 ataaggcaat tagactgtga gtaaaccctc tatgtctaaa cctacttcca aataatttgt
    11521 atattaacat aaatttttta cttatgtaag aacctctcat atctatatct ggaaataaag
    11581 aacctaaata tgcaaaataa atataaatta taattaatac tattttatat gcaatatcgt
    11641 atttaactag gtatagattg tttataaagg ggagtatcaa aagtgcgaat atataacctc
    11701 ccctttcatg tgtttctttt atcatataaa aatcctcctg aatcgtcact ataaacatta
    11761 tattggtaaa tttagactat cttttattat attatatagc aaacataagt ttttttcaaa
    11821 aggattttaa tatttaatta atcttgagat tttaaatttt tgtaattttc taaagcacca
    11881 ttccaattta ctacattaaa ccagttgtca atgtattcat ttcttctatt ttgatatttt
    11941 aaatagtaag catgctccca aacatcaagt cctattatag gagttaggtt tttacttaca
    12001 gggctatcct gatttggagt agtcataata gataatttgc catctttagt agctacaagc
    12061 caagcccaac cagaaccaaa gacatctaaa gcagattttt ggaactcttg cttaaatttt
    12121 tcaaaagaac caaagtctct atcaatagct tcttttaaag attcagaagg tatggttttt
    12181 tctggcgtca ttatatcaaa aaagaattta tgattataag ctccacctgc attatttctt
    12241 acagttgtag caatatcttt aggtaaagaa tctaaatttt gcaataattc acataaagaa
    12301 taattataaa gctcaggata tttttcaaga gcagcattta atttatcaac ataagcttga
    12361 taatgcttat catgatgcag tttcattgtt tctttatcta tataaggttc aagtgcatca
    12421 tatgcataag gtaatggttt aaccttaaat ttgttatttt caggtgtaaa agcaaatgaa
    12481 gttatgcact gtgagattat aaataaagac ataataactg gtattaatat ttttttcttc
    12541 ataaaaatca cctcctaata tagtatttct agaaataaaa aaaatatgaa atattaacag
    12601 ataatttata agaatttaat agcaatttca ttttaaattg aataagtttt aaagccaaag
    12661 acaaaactat gaaatataga ataagactaa aggacagaaa ggaattttga ttatatggac
    12721 ggcaatattt caatttatta taaaggtgat atatctaaaa aagaagatat taaatttaaa
    12781 ataaaagaat ctgtaaataa tacaagactt tctagtagaa tagagtataa ggatgaggaa
    12841 aaaacttttg attttgaaag atttaatgta attgatgcta tttatggaaa taaaccattt
    12901 gaaaaagatg gaaaagttat tgtttttaat ggaaatatat ataactatca tgaaataaaa
    12961 gaagaattaa ttaaaaaagg acacaatttt actacaaatg atgatattga agtcttattg
    13021 gcatcttata tagaatttgg taagaattgt gtacataaga ttaaaggaat gttcaacttt
    13081 ataatctatg atagagaaaa tgaaagtata tttggagcaa gagatttatt tgggataaaa
    13141 ccactttatt atataaataa ggaaaatgca ataatttttt cctcagagta taagttttta
    13201 cttgaatata tgaaaaattt aaatataaat gaaagaagct tacaaagtta tttttcattt
    13261 caatatgtac ttcctgaaga tactatgata caaggaataa ggctgatacc agcaggtcac
    13321 tattttaggg tagaaaatgg tatactatct ttaaagagat ataataaact tgagtttaga
    13381 agtagtacaa aattttttta tactaaaaat cacttaggca atagagatgt gaacgaggat
    13441 gatataagaa atatagtagt agattcaata gtaactcata tggaagagga gaaagaaatt
    13501 ggaacatttt tgtctggtgg aatagattca tctattataa ctactgtggc ttcacaaatt
    13561 aatccaaata taaaatcttt ttctgca
//
